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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000467-TA|BGIBMGA000467-PA|IPR002126|Cadherin,
IPR006209|EGF-like, IPR012680|Laminin G, subdomain 2,
IPR002049|EGF-like, laminin, IPR001879|Hormone receptor,
extracellular, IPR000203|GPS, IPR000152|Aspartic acid and asparagine
hydroxylation site, IPR013032|EGF-like region,
IPR000005|Helix-turn-helix, AraC type, IPR000083|Fibronectin, type I,
IPR006210|EGF, IPR001791|Laminin G, IPR001881|EGF-like
calcium-binding, IPR000742|EGF-like, type 3
         (2796 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q9V5N8 Cluster: Protocadherin-like wing polarity protei...  2285   0.0  
UniRef50_Q7PPU8 Cluster: ENSANGP00000001238; n=2; Culicidae|Rep:...  1495   0.0  
UniRef50_UPI0000DB794E Cluster: PREDICTED: similar to Protocadhe...  1433   0.0  
UniRef50_Q4S7X0 Cluster: Chromosome 9 SCAF14710, whole genome sh...  1381   0.0  
UniRef50_Q9NYQ6 Cluster: Cadherin EGF LAG seven-pass G-type rece...   922   0.0  
UniRef50_Q9NYQ7 Cluster: Cadherin EGF LAG seven-pass G-type rece...   903   0.0  
UniRef50_Q9HCU4 Cluster: Cadherin EGF LAG seven-pass G-type rece...   901   0.0  
UniRef50_Q4RXP0 Cluster: Chromosome 11 SCAF14979, whole genome s...   810   0.0  
UniRef50_A7RKF4 Cluster: Predicted protein; n=2; Nematostella ve...   617   e-174
UniRef50_Q16QV0 Cluster: Cadherin; n=10; Eukaryota|Rep: Cadherin...   491   e-136
UniRef50_Q4SDW5 Cluster: Chromosome undetermined SCAF14629, whol...   479   e-133
UniRef50_UPI0000E473B7 Cluster: PREDICTED: similar to KIAA0279 p...   475   e-132
UniRef50_Q8MY78 Cluster: Ap-cadherin; n=1; Patiria pectinifera|R...   472   e-131
UniRef50_A7RQM0 Cluster: Predicted protein; n=2; Nematostella ve...   471   e-130
UniRef50_Q6W4W6 Cluster: CHz-cadherin; n=19; Euteleostomi|Rep: C...   468   e-129
UniRef50_UPI00015B6261 Cluster: PREDICTED: similar to CG7749-PA;...   462   e-128
UniRef50_Q14517 Cluster: Cadherin-related tumor suppressor homol...   459   e-127
UniRef50_Q9VW71 Cluster: Putative fat-like cadherin-related tumo...   443   e-122
UniRef50_A6NIM4 Cluster: Uncharacterized protein FAT3; n=43; Eut...   433   e-119
UniRef50_A7S3G3 Cluster: Predicted protein; n=2; Nematostella ve...   429   e-118
UniRef50_UPI00006A0F37 Cluster: dachsous 2 isoform 1; n=1; Xenop...   420   e-115
UniRef50_O15943 Cluster: Neural-cadherin precursor; n=42; Arthro...   409   e-112
UniRef50_UPI00006A0F32 Cluster: dachsous 2 isoform 1; n=1; Xenop...   407   e-111
UniRef50_UPI00004D1B71 Cluster: SH3 adapter protein SPIN90 (NCK-...   407   e-111
UniRef50_Q4SRY5 Cluster: Chromosome 18 SCAF14485, whole genome s...   407   e-111
UniRef50_UPI0000E46DFB Cluster: PREDICTED: hypothetical protein;...   398   e-108
UniRef50_Q6V0I7 Cluster: FAT tumor suppressor homolog 4; n=35; E...   397   e-108
UniRef50_UPI0000E48843 Cluster: PREDICTED: similar to Fat4; n=2;...   396   e-108
UniRef50_Q4SFW8 Cluster: Chromosome 7 SCAF14601, whole genome sh...   394   e-107
UniRef50_A7T100 Cluster: Predicted protein; n=1; Nematostella ve...   385   e-104
UniRef50_A7S751 Cluster: Predicted protein; n=1; Nematostella ve...   385   e-104
UniRef50_UPI00015A700B Cluster: UPI00015A700B related cluster; n...   378   e-103
UniRef50_UPI00006A0F38 Cluster: dachsous 2 isoform 1; n=1; Xenop...   378   e-103
UniRef50_UPI0000F1F871 Cluster: PREDICTED: similar to FAT tumor ...   376   e-102
UniRef50_A7SN97 Cluster: Predicted protein; n=1; Nematostella ve...   376   e-102
UniRef50_Q7Q3K5 Cluster: ENSANGP00000007226; n=1; Anopheles gamb...   374   e-101
UniRef50_Q4S3T8 Cluster: Chromosome 20 SCAF14744, whole genome s...   373   e-101
UniRef50_A7SLK9 Cluster: Predicted protein; n=1; Nematostella ve...   373   e-101
UniRef50_UPI00006A0F33 Cluster: dachsous 2 isoform 1; n=1; Xenop...   372   e-100
UniRef50_Q17NI8 Cluster: Cadherin; n=3; cellular organisms|Rep: ...   372   e-100
UniRef50_UPI00015A7221 Cluster: UPI00015A7221 related cluster; n...   370   e-100
UniRef50_UPI0000F200F1 Cluster: PREDICTED: similar to Fat4; n=3;...   369   e-100
UniRef50_A7SLL0 Cluster: Predicted protein; n=2; Nematostella ve...   367   2e-99
UniRef50_Q24292 Cluster: Protein dachsous precursor; n=3; Drosop...   359   5e-97
UniRef50_A7RQ19 Cluster: Predicted protein; n=5; Nematostella ve...   356   6e-96
UniRef50_UPI000065D51F Cluster: Homolog of Homo sapiens "Fat-lik...   355   1e-95
UniRef50_Q9H251 Cluster: Cadherin-23 precursor; n=51; Euteleosto...   355   1e-95
UniRef50_Q6V1P9 Cluster: Dachsous-2; n=9; Eutheria|Rep: Dachsous...   352   7e-95
UniRef50_UPI0000F3174E Cluster: dachsous 2 isoform 1; n=9; Theri...   351   1e-94
UniRef50_UPI000069E6F8 Cluster: dachsous 2 isoform 1; n=1; Xenop...   349   5e-94
UniRef50_A7SAP5 Cluster: Predicted protein; n=1; Nematostella ve...   347   3e-93
UniRef50_UPI0000E7FC61 Cluster: PREDICTED: similar to dachsous 1...   345   1e-92
UniRef50_Q4S3T6 Cluster: Chromosome 20 SCAF14744, whole genome s...   340   4e-91
UniRef50_P33450 Cluster: Cadherin-related tumor suppressor precu...   340   4e-91
UniRef50_UPI0000E49AEF Cluster: PREDICTED: similar to Fat4; n=5;...   339   5e-91
UniRef50_Q9NYQ8 Cluster: Protocadherin Fat 2 precursor; n=19; Am...   339   7e-91
UniRef50_UPI0000F1D37C Cluster: PREDICTED: hypothetical protein;...   336   4e-90
UniRef50_Q4SRZ9 Cluster: Chromosome 18 SCAF14485, whole genome s...   334   3e-89
UniRef50_A7S5N5 Cluster: Predicted protein; n=1; Nematostella ve...   333   5e-89
UniRef50_UPI00006610B3 Cluster: Homolog of Brachydanio rerio "Ca...   327   3e-87
UniRef50_UPI00006A2595 Cluster: Protocadherin-16 precursor (Dach...   322   7e-86
UniRef50_UPI0000660D80 Cluster: Homolog of Brachydanio rerio "Pr...   321   2e-85
UniRef50_A7RI52 Cluster: Predicted protein; n=1; Nematostella ve...   318   1e-84
UniRef50_Q17LY6 Cluster: Cadherin; n=6; Culicidae|Rep: Cadherin ...   314   3e-83
UniRef50_Q96JQ0 Cluster: Protocadherin-16 precursor; n=12; Amnio...   314   3e-83
UniRef50_Q4SVG4 Cluster: Chromosome 1 SCAF13759, whole genome sh...   313   4e-83
UniRef50_UPI000155CE87 Cluster: PREDICTED: similar to FAT tumor ...   311   2e-82
UniRef50_Q60YX0 Cluster: Putative uncharacterized protein CBG180...   310   3e-82
UniRef50_A7S5P0 Cluster: Predicted protein; n=3; Nematostella ve...   309   6e-82
UniRef50_Q7YWB9 Cluster: Cadherin-like protein cad2; n=1; Aplysi...   303   3e-80
UniRef50_Q7PTV6 Cluster: ENSANGP00000002131; n=1; Anopheles gamb...   303   3e-80
UniRef50_Q4SYV0 Cluster: Chromosome undetermined SCAF11948, whol...   296   6e-78
UniRef50_UPI0000E81ED5 Cluster: PREDICTED: similar to protocadhe...   295   9e-78
UniRef50_UPI00015B6339 Cluster: PREDICTED: similar to ENSANGP000...   294   2e-77
UniRef50_Q08174 Cluster: Protocadherin-1 precursor; n=52; Eutele...   294   3e-77
UniRef50_A7S9Y3 Cluster: Predicted protein; n=2; Nematostella ve...   293   3e-77
UniRef50_UPI0000E7FFCA Cluster: PREDICTED: similar to FAT tumor ...   293   6e-77
UniRef50_A7RQ21 Cluster: Predicted protein; n=2; Nematostella ve...   288   2e-75
UniRef50_Q4SVN1 Cluster: Chromosome 1 SCAF13750, whole genome sh...   287   4e-75
UniRef50_Q19319 Cluster: Cadherin-4 precursor; n=1; Caenorhabdit...   285   1e-74
UniRef50_UPI000065CB4F Cluster: Protocadherin-9 precursor.; n=2;...   285   2e-74
UniRef50_Q4SVM9 Cluster: Chromosome 1 SCAF13750, whole genome sh...   281   3e-73
UniRef50_Q9BZA7 Cluster: Protocadherin-11 X-linked precursor; n=...   281   3e-73
UniRef50_Q4S3N9 Cluster: Chromosome 17 SCAF14747, whole genome s...   280   3e-73
UniRef50_Q4RPF4 Cluster: Chromosome 1 SCAF15008, whole genome sh...   278   2e-72
UniRef50_Q4T0W6 Cluster: Chromosome 1 SCAF10821, whole genome sh...   277   2e-72
UniRef50_Q4SFY8 Cluster: Chromosome 7 SCAF14601, whole genome sh...   277   2e-72
UniRef50_A7SN99 Cluster: Predicted protein; n=1; Nematostella ve...   276   7e-72
UniRef50_UPI0000660C02 Cluster: Homolog of Brachydanio rerio "Pr...   273   4e-71
UniRef50_UPI0000E4A946 Cluster: PREDICTED: similar to cadherin 2...   272   7e-71
UniRef50_A7SN98 Cluster: Predicted protein; n=2; Nematostella ve...   272   7e-71
UniRef50_UPI0000DB71FC Cluster: PREDICTED: similar to Cad87A CG6...   272   9e-71
UniRef50_Q96QU1 Cluster: Protocadherin-15 precursor; n=69; Eutel...   272   9e-71
UniRef50_UPI0000F2053F Cluster: PREDICTED: similar to FAT tumor ...   268   1e-69
UniRef50_UPI00006A1F6A Cluster: UPI00006A1F6A related cluster; n...   260   3e-67
UniRef50_A6VVW9 Cluster: Autotransporter-associated beta strand ...   260   4e-67
UniRef50_UPI0000D5573F Cluster: PREDICTED: similar to CG3389-PA;...   260   5e-67
UniRef50_Q967F4 Cluster: Cadherin-related hmr-1 precursor; n=3; ...   258   1e-66
UniRef50_Q4S488 Cluster: Chromosome undetermined SCAF14743, whol...   258   2e-66
UniRef50_Q5F4W0 Cluster: Putative uncharacterized protein; n=3; ...   256   8e-66
UniRef50_UPI0000DB7905 Cluster: PREDICTED: similar to Cad99C CG3...   255   1e-65
UniRef50_Q60I71 Cluster: Cadherin-related neuronal receptor vari...   255   1e-65
UniRef50_Q7PUW9 Cluster: ENSANGP00000018135; n=2; Anopheles gamb...   254   3e-65
UniRef50_Q9VGG5 Cluster: Cadherin 87A precursor; n=2; Diptera|Re...   254   3e-65
UniRef50_Q9Y5F6 Cluster: Protocadherin gamma C5 precursor; n=49;...   252   8e-65
UniRef50_Q5ICW6 Cluster: Protocadherin 15a; n=8; Clupeocephala|R...   248   1e-63
UniRef50_Q9VAF5 Cluster: CG31009-PA; n=9; Diptera|Rep: CG31009-P...   246   9e-63
UniRef50_O60245 Cluster: Protocadherin-7 precursor; n=52; Eutele...   245   1e-62
UniRef50_Q174A5 Cluster: Cadherin; n=1; Aedes aegypti|Rep: Cadhe...   245   2e-62
UniRef50_UPI0000E81FAF Cluster: PREDICTED: similar to Protocadhe...   244   2e-62
UniRef50_Q7QJ26 Cluster: ENSANGP00000009575; n=6; Culicidae|Rep:...   244   3e-62
UniRef50_Q8MY75 Cluster: Pf1-cadherin; n=1; Ptychodera flava|Rep...   244   4e-62
UniRef50_UPI00015A41E3 Cluster: UPI00015A41E3 related cluster; n...   243   5e-62
UniRef50_A7SHT2 Cluster: Predicted protein; n=1; Nematostella ve...   242   8e-62
UniRef50_Q8N6Y1 Cluster: Protocadherin-20 precursor; n=28; Eutel...   242   8e-62
UniRef50_UPI000155BF0A Cluster: PREDICTED: similar to protocadhe...   242   1e-61
UniRef50_UPI0000583D73 Cluster: PREDICTED: hypothetical protein;...   242   1e-61
UniRef50_Q8TAB3 Cluster: Protocadherin-19 precursor; n=31; Eutel...   241   3e-61
UniRef50_Q5CCS6 Cluster: Af1-cadherin; n=1; Artemia franciscana|...   239   6e-61
UniRef50_UPI00006A1011 Cluster: FAT tumor suppressor homolog 3; ...   239   1e-60
UniRef50_Q4RKB4 Cluster: Chromosome 18 SCAF15030, whole genome s...   239   1e-60
UniRef50_UPI00006A0F39 Cluster: Protocadherin alpha 13 precursor...   238   1e-60
UniRef50_A7SSF2 Cluster: Predicted protein; n=2; Nematostella ve...   237   2e-60
UniRef50_Q9VJB6 Cluster: Putative neural-cadherin 2 precursor; n...   237   2e-60
UniRef50_A4KCK1 Cluster: Protocadherin 2A37; n=12; Clupeocephala...   237   4e-60
UniRef50_Q7PT49 Cluster: ENSANGP00000019477; n=1; Anopheles gamb...   235   2e-59
UniRef50_Q17NI9 Cluster: Protocadherin; n=3; Endopterygota|Rep: ...   234   2e-59
UniRef50_Q4SJS0 Cluster: Chromosome 1 SCAF14573, whole genome sh...   234   3e-59
UniRef50_Q60H51 Cluster: Protocadherin2-gamma-v5-sCP1; n=11; Clu...   233   5e-59
UniRef50_Q9Y5H6 Cluster: Protocadherin alpha 8 precursor; n=204;...   231   2e-58
UniRef50_UPI0000E80F11 Cluster: PREDICTED: similar to protocadhe...   231   2e-58
UniRef50_UPI0000E80EB1 Cluster: PREDICTED: similar to cadherin-r...   230   4e-58
UniRef50_Q60H55 Cluster: Protocadherin2-gamma-v12-sCP1; n=8; Dan...   230   5e-58
UniRef50_UPI0000DB7673 Cluster: PREDICTED: similar to Cad74A CG6...   229   8e-58
UniRef50_Q4SVM8 Cluster: Chromosome 1 SCAF13750, whole genome sh...   229   8e-58
UniRef50_UPI00004F6742 Cluster: protocadherin 1 gamma 32; n=3; D...   229   1e-57
UniRef50_Q8IGX4 Cluster: RE10062p; n=6; Diptera|Rep: RE10062p - ...   229   1e-57
UniRef50_Q9Y5I4 Cluster: Protocadherin alpha C2 precursor; n=23;...   228   1e-57
UniRef50_Q9Y5H7 Cluster: Protocadherin alpha 5 precursor; n=15; ...   228   1e-57
UniRef50_P34616 Cluster: Cadherin-3 precursor; n=13; root|Rep: C...   228   2e-57
UniRef50_Q0V9M2 Cluster: Putative uncharacterized protein MGC146...   227   3e-57
UniRef50_UPI0000E821D2 Cluster: PREDICTED: similar to protocadhe...   227   3e-57
UniRef50_A4KCM6 Cluster: Protocadherin 2G25; n=4; Takifugu rubri...   227   3e-57
UniRef50_UPI0000F1FBA8 Cluster: PREDICTED: hypothetical protein;...   226   6e-57
UniRef50_A1L1W7 Cluster: LOC555688 protein; n=6; Euteleostomi|Re...   226   8e-57
UniRef50_Q60I64 Cluster: Cadherin-related neuronal receptor cons...   225   1e-56
UniRef50_Q9Y5F3 Cluster: Protocadherin beta 1 precursor; n=260; ...   225   2e-56
UniRef50_Q60H65 Cluster: Protocadherin1-alpha-av15-vCP; n=75; Eu...   224   2e-56
UniRef50_Q4SNX9 Cluster: Chromosome 15 SCAF14542, whole genome s...   221   2e-55
UniRef50_Q3V7B0 Cluster: Protocadherin alpha; n=22; Tetrapoda|Re...   221   2e-55
UniRef50_UPI0000F2DF7E Cluster: PREDICTED: similar to protocadhe...   220   4e-55
UniRef50_UPI000069E759 Cluster: UPI000069E759 related cluster; n...   220   4e-55
UniRef50_Q75QY0 Cluster: KIAA0811 protein; n=4; Eukaryota|Rep: K...   219   7e-55
UniRef50_Q86N71 Cluster: Cadherin-related protein; n=1; Aplysia ...   219   9e-55
UniRef50_O14917 Cluster: Protocadherin-17 precursor; n=23; Eutel...   219   9e-55
UniRef50_Q9HCL0 Cluster: Protocadherin-18 precursor; n=33; Eutel...   219   1e-54
UniRef50_Q60H59 Cluster: Protocadherin2-gamma-c6-sCP1; n=37; Clu...   217   3e-54
UniRef50_Q32PS9 Cluster: Pcdh1g18 protein; n=35; Clupeocephala|R...   217   4e-54
UniRef50_UPI00006614A3 Cluster: Homolog of Brachydanio rerio "Pr...   216   8e-54
UniRef50_Q24298 Cluster: DE-cadherin precursor; n=5; Neoptera|Re...   216   8e-54
UniRef50_UPI000065EB3B Cluster: Homolog of Brachydanio rerio "Pa...   215   1e-53
UniRef50_Q95YK1 Cluster: Protocadherin; n=1; Ciona savignyi|Rep:...   215   2e-53
UniRef50_Q9Y5H3 Cluster: Protocadherin gamma A10 precursor; n=11...   215   2e-53
UniRef50_UPI00004F6724 Cluster: protocadherin 1 gamma 1; n=3; Da...   214   3e-53
UniRef50_P73089 Cluster: Fat protein; n=1; Synechocystis sp. PCC...   214   3e-53
UniRef50_UPI0000E80EB2 Cluster: PREDICTED: hypothetical protein;...   213   4e-53
UniRef50_Q9VFH5 Cluster: CG3389-PA; n=2; Sophophora|Rep: CG3389-...   213   4e-53
UniRef50_Q9H158 Cluster: Protocadherin alpha C1 precursor; n=12;...   213   8e-53
UniRef50_UPI0000EB26D2 Cluster: UPI0000EB26D2 related cluster; n...   212   1e-52
UniRef50_Q5CCS8 Cluster: Fc1-cadherin; n=2; Hexapoda|Rep: Fc1-ca...   212   1e-52
UniRef50_UPI0000F1EDA6 Cluster: PREDICTED: hypothetical protein;...   211   2e-52
UniRef50_UPI0000E20B47 Cluster: PREDICTED: similar to Protocadhe...   210   3e-52
UniRef50_A7SSF1 Cluster: Predicted protein; n=1; Nematostella ve...   210   3e-52
UniRef50_Q9BYE9 Cluster: Protocadherin LKC precursor; n=17; Ther...   210   3e-52
UniRef50_Q47W44 Cluster: Cadherin domain protein; n=1; Colwellia...   210   4e-52
UniRef50_Q4S0C3 Cluster: Chromosome 2 SCAF14781, whole genome sh...   209   1e-51
UniRef50_UPI000069E7C3 Cluster: Protocadherin beta 11 precursor ...   206   5e-51
UniRef50_Q4S489 Cluster: Chromosome 1 SCAF14742, whole genome sh...   206   9e-51
UniRef50_Q9Y5H0 Cluster: Protocadherin gamma A3 precursor; n=173...   204   2e-50
UniRef50_UPI00006A0F40 Cluster: Protocadherin gamma C3 precursor...   204   3e-50
UniRef50_O93509 Cluster: Paraxial protocadherin; n=11; Xenopus|R...   204   4e-50
UniRef50_Q6EI13 Cluster: GammaA-like protocadherin precursor; n=...   203   5e-50
UniRef50_UPI0000E80EAB Cluster: PREDICTED: similar to Protocadhe...   203   6e-50
UniRef50_UPI00015B46FC Cluster: PREDICTED: similar to CG14900-PA...   202   8e-50
UniRef50_UPI0000E48BDB Cluster: PREDICTED: similar to FAT tumor ...   202   1e-49
UniRef50_Q9P2E7 Cluster: Protocadherin-10 precursor; n=34; Eutel...   202   1e-49
UniRef50_Q9HBT6 Cluster: Cadherin-20 precursor; n=261; Euteleost...   201   3e-49
UniRef50_Q6R0I8 Cluster: Cadherin-related neuronal receptor 3; n...   200   6e-49
UniRef50_O93508 Cluster: Paraxial protocadherin; n=6; Danio reri...   200   6e-49
UniRef50_UPI0000660F9A Cluster: Homolog of Brachydanio rerio "Ca...   199   8e-49
UniRef50_UPI0000DB7642 Cluster: PREDICTED: similar to Cad89D CG1...   198   2e-48
UniRef50_UPI000069FDB0 Cluster: Protocadherin LKC precursor (PC-...   198   2e-48
UniRef50_UPI0000F2B47D Cluster: PREDICTED: similar to matrix met...   196   5e-48
UniRef50_Q9UJ99 Cluster: Cadherin-22 precursor; n=19; Euteleosto...   196   1e-47
UniRef50_Q66S83 Cluster: Protocadherin 10-like protein; n=1; Oik...   195   2e-47
UniRef50_UPI000069ECF7 Cluster: UPI000069ECF7 related cluster; n...   194   3e-47
UniRef50_UPI0000ECABB6 Cluster: Protocadherin-12 precursor (Vasc...   194   4e-47
UniRef50_Q4T6J0 Cluster: Chromosome undetermined SCAF8736, whole...   192   9e-47
UniRef50_Q4RRF3 Cluster: Chromosome 16 SCAF15002, whole genome s...   191   3e-46
UniRef50_Q9NPG4 Cluster: Protocadherin-12 precursor; n=16; Theri...   190   5e-46
UniRef50_Q6R0H9 Cluster: Cadherin-related neuronal receptor c01;...   188   2e-45
UniRef50_Q4SM61 Cluster: Chromosome 13 SCAF14555, whole genome s...   188   2e-45
UniRef50_UPI000069E6F7 Cluster: UPI000069E6F7 related cluster; n...   188   3e-45
UniRef50_A7S9Y2 Cluster: Predicted protein; n=1; Nematostella ve...   187   3e-45
UniRef50_Q96JP9 Cluster: Protocadherin-21; n=30; Euteleostomi|Re...   187   4e-45
UniRef50_UPI0000660953 Cluster: Protocadherin-12 precursor (Vasc...   186   6e-45
UniRef50_UPI000054713A Cluster: PREDICTED: hypothetical protein;...   185   1e-44
UniRef50_Q7YZI2 Cluster: PRCDH1; n=1; Proterospongia sp. ATCC 50...   185   1e-44
UniRef50_UPI000065EA2C Cluster: Homolog of Homo sapiens "Protoca...   185   2e-44
UniRef50_Q9UN73-2 Cluster: Isoform 2 of Q9UN73 ; n=6; Mammalia|R...   184   4e-44
UniRef50_UPI0000E486F2 Cluster: PREDICTED: hypothetical protein;...   182   1e-43
UniRef50_Q4S490 Cluster: Chromosome 1 SCAF14742, whole genome sh...   182   2e-43
UniRef50_UPI00006A195F Cluster: Cadherin-16 precursor (Kidney-sp...   181   2e-43
UniRef50_Q4S1I3 Cluster: Chromosome 6 SCAF14768, whole genome sh...   180   5e-43
UniRef50_P55288 Cluster: Cadherin-11 precursor; n=28; Tetrapoda|...   179   9e-43
UniRef50_UPI0000F20039 Cluster: PREDICTED: hypothetical protein;...   177   4e-42
UniRef50_UPI0000E20B3B Cluster: PREDICTED: similar to Protocadhe...   172   1e-40
UniRef50_Q6V1P8 Cluster: Protocadherin protein; n=6; Catarrhini|...   172   1e-40
UniRef50_Q9H159 Cluster: Cadherin-19 precursor; n=15; Tetrapoda|...   171   2e-40
UniRef50_UPI0000D57279 Cluster: PREDICTED: similar to CG14900-PA...   170   5e-40
UniRef50_Q7UY44 Cluster: Fat protein-possibly involved in cell-c...   169   7e-40
UniRef50_Q4RIZ0 Cluster: Chromosome undetermined SCAF15040, whol...   167   3e-39
UniRef50_Q95YK9 Cluster: Type II cadherin; n=1; Ciona savignyi|R...   167   3e-39
UniRef50_Q5NUI3 Cluster: Cadherin19; n=12; Mammalia|Rep: Cadheri...   167   4e-39
UniRef50_A4GJB0 Cluster: Hypothetical cadherin domain containing...   166   9e-39
UniRef50_UPI000065CB52 Cluster: Homolog of Homo sapiens "Protoca...   164   3e-38
UniRef50_Q4RZD6 Cluster: Chromosome undetermined SCAF14942, whol...   163   5e-38
UniRef50_P33151 Cluster: Cadherin-5 precursor; n=34; Tetrapoda|R...   163   6e-38
UniRef50_UPI0000F1E792 Cluster: PREDICTED: hypothetical protein;...   163   8e-38
UniRef50_Q0YH47 Cluster: Cadherin; n=1; Geobacter sp. FRC-32|Rep...   161   2e-37
UniRef50_Q12864 Cluster: Cadherin-17 precursor; n=25; Tetrapoda|...   161   2e-37
UniRef50_P55283 Cluster: Cadherin-4 precursor; n=74; cellular or...   160   4e-37
UniRef50_Q9VEU1 Cluster: Cadherin 89D precursor; n=3; Sophophora...   157   4e-36
UniRef50_UPI000065EA0C Cluster: Cadherin-20 precursor.; n=1; Tak...   156   9e-36
UniRef50_UPI0000E81ECF Cluster: PREDICTED: similar to protocadhe...   155   2e-35
UniRef50_P12830 Cluster: Epithelial cadherin precursor (E-cadher...   154   4e-35
UniRef50_Q96LQ7 Cluster: CDNA FLJ25193 fis, clone JTH00761; n=13...   153   5e-35
UniRef50_P55290 Cluster: Cadherin-13 precursor; n=40; Euteleosto...   153   5e-35
UniRef50_Q4SS36 Cluster: Chromosome 11 SCAF14479, whole genome s...   153   7e-35
UniRef50_A7RRZ9 Cluster: Predicted protein; n=1; Nematostella ve...   151   2e-34
UniRef50_UPI0000660AA1 Cluster: Cadherin-7 precursor.; n=1; Taki...   151   4e-34
UniRef50_A6E164 Cluster: Large exoprotein; n=2; cellular organis...   149   8e-34
UniRef50_A7T102 Cluster: Predicted protein; n=1; Nematostella ve...   149   1e-33
UniRef50_Q6R8F2 Cluster: Epithelial cadherin precursor (E-cadher...   149   1e-33
UniRef50_UPI0000E473B6 Cluster: PREDICTED: similar to cadherin; ...   149   1e-33
UniRef50_Q4SF84 Cluster: Chromosome undetermined SCAF14607, whol...   149   1e-33
UniRef50_Q7SZW3 Cluster: Novel protein similar to zebrafish epit...   148   2e-33
UniRef50_Q90Z37 Cluster: E-cadherin; n=19; Danio rerio|Rep: E-ca...   145   1e-32
UniRef50_Q7PQL1 Cluster: ENSANGP00000011254; n=2; Culicidae|Rep:...   144   2e-32
UniRef50_A0NBP5 Cluster: ENSANGP00000031609; n=1; Anopheles gamb...   143   5e-32
UniRef50_Q1LX34 Cluster: Novel cadherin domain containing protei...   143   7e-32
UniRef50_O75309 Cluster: Cadherin-16 precursor; n=21; Theria|Rep...   142   1e-31
UniRef50_Q0E9Q8 Cluster: Protocadherin-17; n=6; Clupeocephala|Re...   141   2e-31
UniRef50_Q68SP4 Cluster: Cadherin 5; n=3; Danio rerio|Rep: Cadhe...   141   3e-31
UniRef50_UPI0000F1F8F4 Cluster: PREDICTED: hypothetical protein;...   140   5e-31
UniRef50_Q4S7A3 Cluster: Chromosome 1 SCAF14716, whole genome sh...   140   7e-31
UniRef50_Q676D4 Cluster: Cadherin; n=1; Oikopleura dioica|Rep: C...   140   7e-31
UniRef50_Q088L7 Cluster: Putative outer membrane adhesin like pr...   139   1e-30
UniRef50_Q1KKR4 Cluster: Cadherin 5; n=5; Tetraodontidae|Rep: Ca...   138   2e-30
UniRef50_Q86UP0 Cluster: Cadherin-24 precursor; n=17; Euteleosto...   138   2e-30
UniRef50_A3VZY4 Cluster: VCBS; n=6; Roseovarius|Rep: VCBS - Rose...   136   6e-30
UniRef50_UPI0000E49DF5 Cluster: PREDICTED: similar to protocadhe...   135   2e-29
UniRef50_A7T9P1 Cluster: Predicted protein; n=1; Nematostella ve...   134   3e-29
UniRef50_Q6T1F3 Cluster: M-cadherin; n=6; Danio rerio|Rep: M-cad...   134   4e-29
UniRef50_UPI0000DB741F Cluster: PREDICTED: similar to Cad96Cb CG...   133   6e-29
UniRef50_Q5DYB4 Cluster: Iron-regulated protein FrpC; n=1; Vibri...   133   6e-29
UniRef50_UPI00015A57B8 Cluster: UPI00015A57B8 related cluster; n...   132   2e-28
UniRef50_Q5W7K5 Cluster: Protocadherin-gamma; n=27; Clupeocephal...   132   2e-28
UniRef50_Q4S1I4 Cluster: Chromosome 6 SCAF14768, whole genome sh...   132   2e-28
UniRef50_A6QP71 Cluster: MGC155243 protein; n=2; Bos taurus|Rep:...   132   2e-28
UniRef50_UPI0000ECAEAF Cluster: Epithelial-cadherin precursor (E...   130   7e-28
UniRef50_Q172R3 Cluster: Cadherin, putative; n=1; Aedes aegypti|...   130   7e-28
UniRef50_Q32P55 Cluster: CDH23 protein; n=1; Homo sapiens|Rep: C...   130   7e-28
UniRef50_UPI000155655F Cluster: PREDICTED: similar to hCG1685761...   129   9e-28
UniRef50_UPI0000F1D9C2 Cluster: PREDICTED: hypothetical protein;...   129   1e-27
UniRef50_Q6P3M3 Cluster: Cadherin 17, LI cadherin; n=4; Danio re...   129   1e-27
UniRef50_Q17281 Cluster: Cadherin homolog; n=1; Botryllus schlos...   129   1e-27
UniRef50_UPI00015A74B2 Cluster: UPI00015A74B2 related cluster; n...   128   2e-27
UniRef50_UPI000155C764 Cluster: PREDICTED: similar to protocadhe...   128   3e-27
UniRef50_Q4SVQ0 Cluster: Chromosome undetermined SCAF13747, whol...   128   3e-27
UniRef50_Q4RE65 Cluster: Chromosome 2 SCAF15135, whole genome sh...   128   3e-27
UniRef50_Q8MY76 Cluster: Se-cadherin; n=1; Sexostrea echinata|Re...   128   3e-27
UniRef50_Q5TAN1 Cluster: Protocadherin 8; n=14; Tetrapoda|Rep: P...   128   3e-27
UniRef50_O95206 Cluster: Protocadherin-8 precursor; n=16; Tetrap...   128   3e-27
UniRef50_Q08BK3 Cluster: Dsc2l protein; n=5; Danio rerio|Rep: Ds...   127   4e-27
UniRef50_Q7PT75 Cluster: ENSANGP00000005839; n=2; Anopheles gamb...   126   9e-27
UniRef50_P55291 Cluster: Cadherin-15 precursor; n=11; Tetrapoda|...   126   9e-27
UniRef50_UPI0000E80331 Cluster: PREDICTED: similar to cadherin p...   126   1e-26
UniRef50_Q4SKV9 Cluster: Chromosome undetermined SCAF14565, whol...   126   1e-26
UniRef50_UPI0000D9A8A3 Cluster: PREDICTED: similar to fat tumor ...   125   2e-26
UniRef50_Q9NL47 Cluster: Cadherin; n=1; Ciona intestinalis|Rep: ...   125   2e-26
UniRef50_Q4S7A7 Cluster: Chromosome 1 SCAF14716, whole genome sh...   124   3e-26
UniRef50_A7RYP6 Cluster: Predicted protein; n=1; Nematostella ve...   123   6e-26
UniRef50_UPI0000ECD04C Cluster: CDNA FLJ44366 fis, clone TRACH30...   123   8e-26
UniRef50_Q7YWB8 Cluster: Cadherin-like protein cad3; n=1; Aplysi...   123   8e-26
UniRef50_Q1YNS7 Cluster: Cadherin domain protein; n=3; gamma pro...   121   3e-25
UniRef50_UPI00015A73E8 Cluster: UPI00015A73E8 related cluster; n...   120   4e-25
UniRef50_UPI00015B58A5 Cluster: PREDICTED: similar to GA18227-PA...   120   6e-25
UniRef50_Q4SGA8 Cluster: Chromosome 17 SCAF14597, whole genome s...   120   6e-25
UniRef50_Q0ALR4 Cluster: Serralysin precursor; n=1; Maricaulis m...   120   8e-25
UniRef50_Q96AU6 Cluster: FAT3 protein; n=13; Eukaryota|Rep: FAT3...   120   8e-25
UniRef50_UPI000065D984 Cluster: Homolog of Brachydanio rerio "E-...   119   1e-24
UniRef50_UPI000155D19D Cluster: PREDICTED: similar to cadherin-l...   119   1e-24
UniRef50_UPI0000660666 Cluster: Homolog of Brachydanio rerio "E-...   118   2e-24
UniRef50_Q4SM63 Cluster: Chromosome 13 SCAF14555, whole genome s...   118   2e-24
UniRef50_Q86T00 Cluster: Full-length cDNA clone CS0DK003YO17 of ...   118   2e-24
UniRef50_Q9UII7 Cluster: E-cadherin; n=5; Catarrhini|Rep: E-cadh...   118   2e-24
UniRef50_Q4T518 Cluster: Chromosome undetermined SCAF9471, whole...   117   4e-24
UniRef50_Q19194 Cluster: Cadherin family protein 5, isoform a; n...   117   4e-24
UniRef50_A5F7Q5 Cluster: Cadherin domain protein; n=23; Vibrio c...   117   5e-24
UniRef50_Q9VBV6 Cluster: CG13664-PA; n=5; Sophophora|Rep: CG1366...   116   7e-24
UniRef50_A7SLT3 Cluster: Predicted protein; n=2; Nematostella ve...   116   7e-24
UniRef50_Q8MY74 Cluster: Pf2-cadherin; n=1; Ptychodera flava|Rep...   116   9e-24
UniRef50_A7S5N8 Cluster: Predicted protein; n=1; Nematostella ve...   116   9e-24
UniRef50_P33545 Cluster: Desmocollin-2 precursor; n=7; Theria|Re...   116   9e-24
UniRef50_UPI0000F20971 Cluster: PREDICTED: hypothetical protein,...   115   2e-23
UniRef50_Q9YGQ8 Cluster: Cadherin; n=3; Coelomata|Rep: Cadherin ...   115   2e-23
UniRef50_Q4S7A6 Cluster: Chromosome 1 SCAF14716, whole genome sh...   115   2e-23
UniRef50_Q16Z56 Cluster: Cadherin, putative; n=1; Aedes aegypti|...   115   2e-23
UniRef50_UPI000155CE9C Cluster: PREDICTED: similar to reproducti...   114   3e-23
UniRef50_Q02413 Cluster: Desmoglein-1 precursor; n=19; Mammalia|...   114   3e-23
UniRef50_Q89NW9 Cluster: Bll3714 protein; n=2; cellular organism...   114   4e-23
UniRef50_Q8IXH8 Cluster: Cadherin-like protein 26 precursor; n=2...   113   7e-23
UniRef50_Q86SJ6 Cluster: Desmoglein-4 precursor; n=16; Mammalia|...   113   9e-23
UniRef50_Q02487 Cluster: Desmocollin-2 precursor; n=70; Mammalia...   113   9e-23
UniRef50_Q14126 Cluster: Desmoglein-2 precursor; n=18; Theria|Re...   112   1e-22
UniRef50_UPI0000E7FEEA Cluster: PREDICTED: similar to desmoglein...   112   2e-22
UniRef50_UPI0000E48655 Cluster: PREDICTED: similar to cadherin E...   111   2e-22
UniRef50_UPI0000ECCE39 Cluster: Desmoglein-1 precursor (Desmosom...   111   2e-22
UniRef50_Q4SDX5 Cluster: Chromosome undetermined SCAF14628, whol...   111   2e-22
UniRef50_Q4T0W5 Cluster: Chromosome 1 SCAF10821, whole genome sh...   111   3e-22
UniRef50_Q7UWZ8 Cluster: Putative uncharacterized protein; n=1; ...   111   3e-22
UniRef50_Q9VGW1 Cluster: Putative cadherin CG4509 precursor; n=3...   111   3e-22
UniRef50_Q5HZ99 Cluster: MGC85083 protein; n=2; Xenopus|Rep: MGC...   109   1e-21
UniRef50_UPI000155CFDF Cluster: PREDICTED: similar to protocadhe...   107   4e-21
UniRef50_UPI00004D6FF9 Cluster: Crumbs homolog 1 precursor.; n=2...   107   6e-21
UniRef50_Q4SDH3 Cluster: Chromosome undetermined SCAF14638, whol...   107   6e-21
UniRef50_Q7TSF1 Cluster: Desmoglein-1 beta precursor; n=4; Theri...   106   1e-20
UniRef50_Q7QAN5 Cluster: ENSANGP00000011927; n=1; Anopheles gamb...   105   2e-20
UniRef50_Q7TSF0 Cluster: Desmoglein-1 gamma precursor; n=5; Muri...   104   3e-20
UniRef50_A0NBP4 Cluster: ENSANGP00000031608; n=1; Anopheles gamb...   103   5e-20
UniRef50_UPI0000F20007 Cluster: PREDICTED: hypothetical protein;...   103   7e-20
UniRef50_Q7ULP1 Cluster: Probable G-cadherin-possibly involved i...   103   7e-20
UniRef50_UPI000155D1D0 Cluster: PREDICTED: hypothetical protein,...   103   9e-20
UniRef50_Q4SF34 Cluster: Chromosome 1 SCAF14609, whole genome sh...   103   9e-20
UniRef50_Q7UZ67 Cluster: Lipoprotein receptor-related protein; n...   103   9e-20
UniRef50_UPI0000F1D53E Cluster: PREDICTED: similar to cadherin 2...   102   1e-19
UniRef50_A4A1I4 Cluster: Fat protein-possibly involved in cell-c...   102   1e-19
UniRef50_UPI0000E8124F Cluster: PREDICTED: similar to oko meduzy...   101   2e-19
UniRef50_UPI0000E7FEE8 Cluster: PREDICTED: similar to desmocolli...   101   2e-19
UniRef50_UPI0001556456 Cluster: PREDICTED: similar to fat protei...   101   3e-19
UniRef50_UPI0000F2B3CC Cluster: PREDICTED: similar to crumbs hom...   100   7e-19
UniRef50_Q7QEU4 Cluster: ENSANGP00000019269; n=1; Anopheles gamb...   100   7e-19
UniRef50_Q1A5L1 Cluster: Crumbs-like protein 2b; n=5; Euteleosto...    99   9e-19
UniRef50_Q6ZTQ4 Cluster: Cadherin-like protein 28 precursor; n=1...    99   9e-19
UniRef50_UPI00006A1DB7 Cluster: Cadherin-like protein 26 precurs...   100   1e-18
UniRef50_UPI00004D822A Cluster: Cadherin-related tumor suppresso...   100   1e-18
UniRef50_Q4S5J7 Cluster: Chromosome 9 SCAF14729, whole genome sh...    99   2e-18
UniRef50_P32926 Cluster: Desmoglein-3 precursor; n=18; Eukaryota...    99   2e-18
UniRef50_Q7Q1N1 Cluster: ENSANGP00000013153; n=1; Anopheles gamb...    98   3e-18
UniRef50_O62328 Cluster: Putative uncharacterized protein cdh-7;...    98   3e-18
UniRef50_A7S4B9 Cluster: Predicted protein; n=1; Nematostella ve...    98   3e-18
UniRef50_Q5IJ48 Cluster: Crumbs homolog 2 precursor; n=17; Euthe...    98   4e-18
UniRef50_UPI00006600BE Cluster: Homolog of Homo sapiens "Desmogl...    97   6e-18
UniRef50_Q4SI11 Cluster: Chromosome 5 SCAF14581, whole genome sh...    97   6e-18
UniRef50_A7S9Y1 Cluster: Predicted protein; n=1; Nematostella ve...    97   6e-18
UniRef50_UPI0000D67092 Cluster: PREDICTED: hypothetical protein;...    97   8e-18
UniRef50_A4D0S4 Cluster: Laminin, beta 4; n=14; Eutheria|Rep: La...    97   8e-18
UniRef50_Q4SI27 Cluster: Chromosome 5 SCAF14581, whole genome sh...    96   1e-17
UniRef50_UPI0000660079 Cluster: Homolog of Homo sapiens "Laminin...    95   2e-17
UniRef50_A0YV99 Cluster: Cadherin domain protein; n=1; Lyngbya s...    95   2e-17
UniRef50_Q3B7G9 Cluster: Si:busm1-71b9.3 protein; n=5; Danio rer...    95   3e-17
UniRef50_Q8I722 Cluster: FAT-like cadherin CDH-3; n=3; Bilateria...    95   3e-17
UniRef50_Q21035 Cluster: Cadherin family protein 9; n=2; Caenorh...    95   3e-17
UniRef50_Q4SDX7 Cluster: Chromosome undetermined SCAF14628, whol...    94   4e-17
UniRef50_UPI0000DA2660 Cluster: PREDICTED: similar to FAT tumor ...    93   8e-17
UniRef50_UPI0000D5721D Cluster: PREDICTED: similar to CG4655-PA,...    93   8e-17
UniRef50_P55268 Cluster: Laminin subunit beta-2 precursor; n=69;...    93   1e-16
UniRef50_UPI00005C16EA Cluster: PREDICTED: similar to Protocadhe...    93   1e-16
UniRef50_Q58EP9 Cluster: LOC553337 protein; n=4; Danio rerio|Rep...    92   2e-16
UniRef50_Q4SNR1 Cluster: Chromosome 15 SCAF14542, whole genome s...    92   2e-16
UniRef50_O15230 Cluster: Laminin subunit alpha-5 precursor; n=16...    91   4e-16
UniRef50_Q21313 Cluster: Laminin-like protein epi-1 precursor; n...    91   5e-16
UniRef50_UPI000155C727 Cluster: PREDICTED: similar to laminin be...    89   1e-15
UniRef50_UPI0000F21093 Cluster: PREDICTED: similar to cadherin-l...    89   1e-15
UniRef50_UPI0000660623 Cluster: Homolog of Homo sapiens "Splice ...    89   2e-15
UniRef50_Q566L0 Cluster: Cdh26 protein; n=2; Xenopus tropicalis|...    89   2e-15
UniRef50_Q7YZI1 Cluster: MBCDH1; n=1; Monosiga brevicollis|Rep: ...    89   2e-15
UniRef50_Q61F88 Cluster: Putative uncharacterized protein CBG117...    89   2e-15
UniRef50_A2A3A3 Cluster: Protocadherin 15; n=10; Euarchontoglire...    89   2e-15
UniRef50_Q86DU3 Cluster: Cadherin-like protein; n=65; Ditrysia|R...    88   3e-15
UniRef50_Q171X1 Cluster: Putative uncharacterized protein; n=1; ...    88   3e-15
UniRef50_UPI0000D563F0 Cluster: PREDICTED: similar to CG15288-PB...    88   4e-15
UniRef50_Q9TVQ2 Cluster: Putative uncharacterized protein; n=2; ...    87   5e-15
UniRef50_UPI0000F1F39B Cluster: PREDICTED: similar to CDH26; n=2...    87   7e-15
UniRef50_Q6AX88 Cluster: MGC81969 protein; n=1; Xenopus laevis|R...    87   9e-15
UniRef50_UPI0000D5583D Cluster: PREDICTED: similar to Cadherin E...    86   1e-14
UniRef50_Q4SXH1 Cluster: Chromosome undetermined SCAF12413, whol...    86   1e-14
UniRef50_A2I7R3 Cluster: MadA; n=1; Mesorhizobium sp. R88B|Rep: ...    86   1e-14
UniRef50_Q4S162 Cluster: Chromosome 13 SCAF14769, whole genome s...    86   2e-14
UniRef50_Q09EY8 Cluster: Cadherin-like protein; n=4; Helicoverpa...    85   2e-14
UniRef50_UPI0000F2080D Cluster: PREDICTED: similar to Dsg2 prote...    85   3e-14
UniRef50_Q4RJQ1 Cluster: Chromosome 13 SCAF15035, whole genome s...    85   3e-14
UniRef50_A6ANU4 Cluster: Calx-beta domain family; n=1; Vibrio ha...    85   4e-14
UniRef50_UPI0000F1F613 Cluster: PREDICTED: similar to Desmoglein...    84   5e-14
UniRef50_Q1A5L2 Cluster: Oko meduzy; n=3; Clupeocephala|Rep: Oko...    84   6e-14
UniRef50_Q4S5K3 Cluster: Chromosome 9 SCAF14729, whole genome sh...    83   8e-14
UniRef50_Q32LQ8 Cluster: Pcdh2g6 protein; n=9; Clupeocephala|Rep...    83   8e-14
UniRef50_A0NQR0 Cluster: Fat protein-possibly involved in cell-c...    83   8e-14
UniRef50_UPI0000DA24E5 Cluster: PREDICTED: similar to FAT tumor ...    83   1e-13
UniRef50_UPI0000EBD4D8 Cluster: PREDICTED: similar to Laminin al...    83   1e-13
UniRef50_UPI0000DA3D77 Cluster: PREDICTED: similar to FAT tumor ...    82   2e-13
UniRef50_Q6TM00 Cluster: Protocadherin-like protein; n=3; Tetrao...    82   2e-13
UniRef50_A7S7D3 Cluster: Predicted protein; n=1; Nematostella ve...    82   2e-13
UniRef50_UPI00015B61BF Cluster: PREDICTED: similar to laminin A ...    82   2e-13
UniRef50_UPI00015B59C9 Cluster: PREDICTED: similar to laminin al...    81   3e-13
UniRef50_UPI0000DB6CE4 Cluster: PREDICTED: similar to wing blist...    81   3e-13
UniRef50_Q967S8 Cluster: Laminin beta chain; n=1; Schistocerca g...    81   3e-13
UniRef50_Q4S5A4 Cluster: Chromosome 19 SCAF14731, whole genome s...    81   4e-13
UniRef50_A0LXF0 Cluster: Secreted protein containing cadherin do...    80   8e-13
UniRef50_UPI0000DA41C0 Cluster: PREDICTED: similar to desmocolli...    80   1e-12
UniRef50_UPI000155551A Cluster: PREDICTED: similar to Ksp-cadher...    79   1e-12
UniRef50_Q8JHV6 Cluster: Laminin beta 4; n=7; Clupeocephala|Rep:...    79   1e-12
UniRef50_UPI0000E814A8 Cluster: PREDICTED: similar to MEGF6; n=1...    79   2e-12
UniRef50_Q5BYL9 Cluster: SJCHGC04271 protein; n=1; Schistosoma j...    78   3e-12
UniRef50_Q2Q1W5 Cluster: Laminin alpha 5; n=7; Clupeocephala|Rep...    78   4e-12
UniRef50_UPI0000D5583E Cluster: PREDICTED: similar to CG3389-PA;...    77   5e-12
UniRef50_O75093 Cluster: Slit homolog 1 protein precursor; n=144...    77   5e-12
UniRef50_UPI0000E4A0C7 Cluster: PREDICTED: similar to fibropelli...    77   7e-12
UniRef50_UPI0000DB7BBA Cluster: PREDICTED: similar to Laminin B1...    77   9e-12
UniRef50_Q4T7X6 Cluster: Chromosome undetermined SCAF7949, whole...    77   9e-12
UniRef50_Q9BPS2 Cluster: Laminin; n=1; Bombyx mori|Rep: Laminin ...    77   9e-12
UniRef50_UPI0000F2DD8E Cluster: PREDICTED: hypothetical protein;...    76   1e-11
UniRef50_UPI000051A338 Cluster: PREDICTED: similar to agrin isof...    76   1e-11
UniRef50_Q0APJ1 Cluster: Cadherin precursor; n=1; Maricaulis mar...    76   1e-11
UniRef50_Q60JK4 Cluster: Putative uncharacterized protein CBG244...    76   2e-11
UniRef50_Q8NHD4 Cluster: SREC-3; n=6; Theria|Rep: SREC-3 - Homo ...    76   2e-11
UniRef50_Q14162 Cluster: Endothelial cells scavenger receptor pr...    76   2e-11
UniRef50_UPI0000EBD4DB Cluster: PREDICTED: similar to cadherin 4...    75   2e-11
UniRef50_Q304D6 Cluster: Putative uncharacterized protein; n=4; ...    75   3e-11
UniRef50_A7SQA1 Cluster: Predicted protein; n=1; Nematostella ve...    75   3e-11
UniRef50_A7SD81 Cluster: Predicted protein; n=1; Nematostella ve...    75   3e-11
UniRef50_UPI0000E7F7D9 Cluster: PREDICTED: hypothetical protein;...    75   4e-11
UniRef50_A7SIF3 Cluster: Predicted protein; n=1; Nematostella ve...    75   4e-11
UniRef50_O75445 Cluster: Usherin precursor; n=34; Eukaryota|Rep:...    75   4e-11
UniRef50_UPI00015B51E9 Cluster: PREDICTED: similar to laminin ga...    74   5e-11
UniRef50_UPI00005A0191 Cluster: PREDICTED: similar to protocadhe...    74   5e-11
UniRef50_A0NB14 Cluster: ENSANGP00000025533; n=1; Anopheles gamb...    74   5e-11
UniRef50_UPI0000E4975D Cluster: PREDICTED: similar to ENSANGP000...    74   7e-11
UniRef50_UPI0000660B21 Cluster: Homolog of Brachydanio rerio "E-...    74   7e-11
UniRef50_Q4SW86 Cluster: Chromosome undetermined SCAF13670, whol...    74   7e-11
UniRef50_A4A585 Cluster: Repeat domain protein; n=1; Congregibac...    74   7e-11
UniRef50_P25391 Cluster: Laminin subunit alpha-1 precursor; n=34...    74   7e-11
UniRef50_UPI0000D9CA40 Cluster: PREDICTED: similar to Cadherin E...    73   9e-11
UniRef50_Q45H72 Cluster: Laminin alpha 1; n=9; Euteleostomi|Rep:...    73   9e-11
UniRef50_A7SYG4 Cluster: Predicted protein; n=1; Nematostella ve...    73   9e-11
UniRef50_O75095 Cluster: Multiple epidermal growth factor-like d...    73   9e-11
UniRef50_Q00174 Cluster: Laminin subunit alpha precursor; n=7; D...    73   9e-11
UniRef50_UPI0000E4A783 Cluster: PREDICTED: similar to laminin ga...    73   1e-10
UniRef50_O45614 Cluster: Putative uncharacterized protein lam-3;...    73   1e-10
UniRef50_A7SSY8 Cluster: Predicted protein; n=1; Nematostella ve...    73   1e-10
UniRef50_UPI0000DB7F08 Cluster: PREDICTED: similar to Laminin A ...    73   2e-10
UniRef50_Q4C8Z4 Cluster: VCBS; n=1; Crocosphaera watsonii WH 850...    73   2e-10
UniRef50_Q18823 Cluster: Laminin-like protein lam-2 precursor; n...    73   2e-10
UniRef50_UPI0000DA39A7 Cluster: PREDICTED: similar to Crumbs hom...    72   2e-10
UniRef50_A6BZA6 Cluster: VCBS; n=1; Planctomyces maris DSM 8797|...    72   2e-10
UniRef50_UPI0000F203FC Cluster: PREDICTED: similar to usherin; n...    72   3e-10
UniRef50_UPI0000D9C9E0 Cluster: PREDICTED: similar to Cadherin E...    71   4e-10
UniRef50_A7S9Y4 Cluster: Predicted protein; n=1; Nematostella ve...    71   4e-10
UniRef50_Q4S226 Cluster: Chromosome undetermined SCAF14764, whol...    71   5e-10
UniRef50_A7SIF6 Cluster: Predicted protein; n=1; Nematostella ve...    71   5e-10
UniRef50_A7RRT9 Cluster: Predicted protein; n=1; Nematostella ve...    71   5e-10
UniRef50_A7RNY3 Cluster: Predicted protein; n=4; Nematostella ve...    71   5e-10
UniRef50_UPI0000F204F9 Cluster: PREDICTED: hypothetical protein;...    71   6e-10
UniRef50_UPI0000EBE0CA Cluster: PREDICTED: similar to laminin be...    71   6e-10
UniRef50_UPI0000E48844 Cluster: PREDICTED: similar to Usher synd...    71   6e-10
UniRef50_Q4TB23 Cluster: Chromosome 15 SCAF7210, whole genome sh...    71   6e-10
UniRef50_A7SV36 Cluster: Predicted protein; n=1; Nematostella ve...    71   6e-10
UniRef50_A7RIY4 Cluster: Predicted protein; n=1; Nematostella ve...    70   8e-10
UniRef50_P15215 Cluster: Laminin subunit gamma-1 precursor; n=16...    70   8e-10
UniRef50_P11046 Cluster: Laminin subunit beta-1 precursor; n=6; ...    70   8e-10
UniRef50_UPI00006A069F Cluster: MEGF11 protein; n=2; Xenopus tro...    70   1e-09
UniRef50_Q4T0S1 Cluster: Chromosome undetermined SCAF10875, whol...    70   1e-09
UniRef50_UPI0000E45F7B Cluster: PREDICTED: similar to MEGF6; n=4...    69   1e-09
UniRef50_UPI0000D99687 Cluster: PREDICTED: similar to agrin; n=1...    69   1e-09
UniRef50_UPI0000F3484D Cluster: UPI0000F3484D related cluster; n...    69   1e-09
UniRef50_Q8IQ18 Cluster: CG33196-PB; n=10; Endopterygota|Rep: CG...    69   1e-09
UniRef50_Q9Y6N6 Cluster: Laminin subunit gamma-3 precursor; n=31...    69   1e-09
UniRef50_UPI00006A00A9 Cluster: Laminin subunit gamma-2 precurso...    69   2e-09
UniRef50_A1XQX6 Cluster: Neurexin 2b alpha; n=4; Clupeocephala|R...    69   2e-09
UniRef50_UPI00015B4CFA Cluster: PREDICTED: similar to IP15264p; ...    68   3e-09
UniRef50_UPI00015A7BCD Cluster: UPI00015A7BCD related cluster; n...    68   3e-09
UniRef50_P46531 Cluster: Neurogenic locus notch homolog protein ...    68   3e-09
UniRef50_UPI0000E4975E Cluster: PREDICTED: similar to laminin A ...    68   4e-09
UniRef50_UPI0000519B12 Cluster: PREDICTED: similar to wing blist...    68   4e-09
UniRef50_UPI000065F871 Cluster: Homolog of Homo sapiens "MEGF10 ...    68   4e-09
UniRef50_Q4SLY2 Cluster: Chromosome 13 SCAF14555, whole genome s...    68   4e-09
UniRef50_Q4RVG6 Cluster: Chromosome 15 SCAF14992, whole genome s...    68   4e-09
UniRef50_Q17L45 Cluster: Laminin alpha-1, 2 chain; n=3; Culicida...    68   4e-09
UniRef50_UPI000155D0E5 Cluster: PREDICTED: similar to intestinal...    67   6e-09

>UniRef50_Q9V5N8 Cluster: Protocadherin-like wing polarity protein
            stan precursor; n=10; Sophophora|Rep: Protocadherin-like
            wing polarity protein stan precursor - Drosophila
            melanogaster (Fruit fly)
          Length = 3574

 Score = 2285 bits (5668), Expect = 0.0
 Identities = 1104/1828 (60%), Positives = 1339/1828 (73%), Gaps = 84/1828 (4%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            Q+NVLDCNDHSP FE +Q+EAS+REGA+ G+TV+TL+ATDQDIGKNAE+EY IE VT   
Sbjct: 451  QVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGA 510

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
               +D              +FRID RSG + TR+SLDRE    Y +LV A D AS  S+R
Sbjct: 511  GLAQDQE----------MPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSER 560

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI-SVTDNPVIAKIKATDADVGANSAIR 188
             ++TA++ V ++DDNDNYPQFSE+TYTV V ED    T++  +A I+ATDAD G N+AIR
Sbjct: 561  RTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIR 620

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            YAIIGGNTQ QFSIDS+SGDVSLVK LDYE VRSYRLVIRAQDGGSPSRSNTTQLL+N+ 
Sbjct: 621  YAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVI 680

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            D NDNAPRFYTS FQESV ENVP+GY+I+RVQAYD+DEG NAE+TY+++++D     + P
Sbjct: 681  DANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDD----NFP 736

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
            + +DPR+GWV T   LDRE Q ++   V A DGG PP+SA+++              F P
Sbjct: 737  LAVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNP 796

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
              YE  + ED+PPGTPV T+TATD DED+RLHYEIT GNTRGRF+ITSQNGRGLIT+AQ 
Sbjct: 797  KYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLITIAQS 856

Query: 429  LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
            LD+KQE+R++LTV+ATDSGGRSDTA V INITDANN+AP+FENAPY+ASVFEDAP+GTTV
Sbjct: 857  LDYKQEKRFLLTVAATDSGGRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTV 916

Query: 489  LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
            LVVSATDSDVG+NAQITYSL+ E  N  +   D  F INPQTGAI TN  LDRET SGYL
Sbjct: 917  LVVSATDSDVGVNAQITYSLNEESIN-GLGSPDP-FSINPQTGAIVTNAPLDRETTSGYL 974

Query: 549  LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
            LTVTA+DGG PSLSDTTDVEI V DVNDN P FK  LY A+I+EDALVGTSV QV A+D 
Sbjct: 975  LTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDP 1034

Query: 609  DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
            DVGLNGRI Y L  +D E+GSFVIDP SG IRTNK LDRESVA   L A+A+D G+PP S
Sbjct: 1035 DVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLS 1094

Query: 669  STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
            STV V I++ED+NDSPP F SD +T Y+ ENSP+G+ +GEI AHDPDEG NAVVHYSI G
Sbjct: 1095 STVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSIIG 1154

Query: 729  GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVN 788
            GDDSN+FSL TR GS++A+L+TM +LDYES RK++ELV+RAASPPL ND  +EILVTDVN
Sbjct: 1155 GDDSNAFSLVTRPGSERAQLLTMTELDYESTRKRFELVVRAASPPLRNDAHIEILVTDVN 1214

Query: 789  DNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGS 848
            DNAPV++DFQ+IFNN++D FP G  GR+PA+DADV+DKL YRILSGNNANL+ LN ++G 
Sbjct: 1215 DNAPVLRDFQVIFNNFRDHFPSGEIGRIPAFDADVSDKLHYRILSGNNANLLRLNSSSGG 1274

Query: 849  MTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQF 908
            + LSPQLNTNVPK ATMEVSV+DG+NE KA+MQLSVRLITE+ML NS+TVRLN+MT E F
Sbjct: 1275 LVLSPQLNTNVPKFATMEVSVSDGINEAKAIMQLSVRLITEDMLFNSVTVRLNEMTEEAF 1334

Query: 909  LSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSP 968
            LSPLL FF+DGLAAIIPCPKE+I++FS+QDDTDV+  ILNVSFSARRPD           
Sbjct: 1335 LSPLLNFFLDGLAAIIPCPKEHIFVFSIQDDTDVSSRILNVSFSARRPDVS------HEE 1388

Query: 969  HYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNS 1028
             Y+P +L+ERVYL+R  LARLATV+VLPFDDN+CV EPCLNFEECLTVLKFGNAS F++S
Sbjct: 1389 FYTPQYLQERVYLNRAILARLATVEVLPFDDNLCVREPCLNFEECLTVLKFGNASEFIHS 1448

Query: 1029 DSVLFRPIYPVTSFTCQCPEGFTGVN----CETILTKASCEVDGDGSIC---RSGSQCVA 1081
            D+VLFRPIYPV +F C CPEGFTG      C+T +     +   +G  C     G  CV 
Sbjct: 1449 DTVLFRPIYPVNTFACSCPEGFTGSKEHYLCDTEVDLCYSDPCQNGGTCVRREGGYTCVC 1508

Query: 1082 RR----------------------EGGILCQGC--SIDAAYTTAVCELRARSFPVSSFLT 1117
                                    EGG+ C     S      TA CELRAR+F  +SFLT
Sbjct: 1509 PSTHTGQNCETGVGHLRPCPSETCEGGLSCLSNYPSSQPPPYTATCELRARAFGRNSFLT 1568

Query: 1118 FPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRGGGPGLRFSFS 1177
            F  LK+RHR +LKL+FAT   +GLLLYNGRYNE HDF+ALE+              FSFS
Sbjct: 1569 FESLKQRHRFNLKLRFATVQENGLLLYNGRYNELHDFIALEIHEGHVS--------FSFS 1620

Query: 1178 LGGGKSEITV--EGNVGDGSWHTVEIEYFNRTITMILDDCDKVLSLAGAADFGLKYACAN 1235
            LG     I+V  E  V DG WH VE+ Y NR++T++LD+CD  ++L+G    G +++CAN
Sbjct: 1621 LGDHSERISVIQEAKVSDGKWHQVEVVYLNRSVTLVLDNCDTAIALSG--QLGDRWSCAN 1678

Query: 1236 FTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNKDFVGCISDFYIDHKFI 1295
             T   L  RC + TETCHRFLDLTGPLQ+GGLP IP+ F V N+DFVGCISD  ID +F+
Sbjct: 1679 RTTLKLDKRCSLLTETCHRFLDLTGPLQVGGLPRIPAHFPVTNRDFVGCISDLRIDDRFV 1738

Query: 1296 DLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPP 1355
            DLNSYVADNGTLAGCP+K   C S PC+NG  C + W TY C+C EG+ G  C D+   P
Sbjct: 1739 DLNSYVADNGTLAGCPQKAPLCQSEPCFNGGTCREGWGTYSCECPEGYAGNSCQDNIPAP 1798

Query: 1356 WRFGGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMSIQ----------LKSGLLHYS 1405
            WRF GDG LSFNPLLRPIQLPW  + S+RTRQ++AF++ IQ          L+ G+L+Y 
Sbjct: 1799 WRFSGDGSLSFNPLLRPIQLPWTTSFSLRTRQKEAFLLQIQIGQNSSAAVCLRQGVLYYI 1858

Query: 1406 YNGETMYLPMATLSDGAWHRIEIKW-LGTDISVTVDYGLRTVLMPMLANKIQGQYIGKIL 1464
            ++GE MYL  A LSDG WHR+EI+W  G++I  +VDYG R+  +PM + K+QG Y+GKI+
Sbjct: 1859 FDGEPMYLAGAFLSDGEWHRVEIRWQQGSEIHFSVDYGQRSGSVPM-SQKVQGLYVGKIV 1917

Query: 1465 IGGLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRPTVRENVRDGCQSRADCMLSICPP 1524
            +G  D + G +  +   FEGCIQDVRIG  QS+L+RPT+RENV DGC+SRA C    CP 
Sbjct: 1918 MGSPDGSIGAV-PEASPFEGCIQDVRIGAGQSVLSRPTIRENVEDGCESRAQCP-DHCPN 1975

Query: 1525 YSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQT-PKGYSCACEPGYTLTT 1583
            +S C +SWD STC C++G VG  C   C + PC +  C  + + P+GY C C    +   
Sbjct: 1976 HSSCQSSWDLSTCECDSGYVGTDCAPICTVRPCASGVCRANTSLPRGYDCECNSS-SRHG 2034

Query: 1584 SGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLP 1643
              C +  ++ CPGGWWG   CGPC CD+ +GYHP CNK  G+C+CK NHY+P     CL 
Sbjct: 2035 DYCEKELQQPCPGGWWGERVCGPCRCDLAQGYHPDCNKTTGQCYCKTNHYQPPNETACLS 2094

Query: 1644 CQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAG 1703
            C CY+ GS + +C   TGQC CR GVIGR CD+C+N YAEVT  SGCEVVYD CPRSFAG
Sbjct: 2095 CDCYSIGSFSGACNPLTGQCECREGVIGRRCDSCSNPYAEVT-LSGCEVVYDACPRSFAG 2153

Query: 1704 GVWWPRTKFGVETITDCPPGSSGRATRTCDETKDVPWQDPDMFNCTTATFYQLRKQLHKI 1763
            GVWWPRT  G   I  CPP + G+  R+CD  +   W  PDM+NCT+  F +LR+QL ++
Sbjct: 2154 GVWWPRTPLGGVAIEGCPPPARGKGQRSCD-VQSGSWNTPDMYNCTSEPFVELRRQLSQL 2212

Query: 1764 ETGELTMNTFVGVRVAADLSTACANTPR 1791
            E  EL +N+FV +++A  L  AC    R
Sbjct: 2213 EKLELELNSFVAIKMAEQLRKACEAVDR 2240



 Score =  363 bits (893), Expect = 4e-98
 Identities = 275/861 (31%), Positives = 417/861 (48%), Gaps = 69/861 (8%)

Query: 15   DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
            +  + SP FE   Y ASV E   +G  V T++A D +   ++ V Y++       L+   
Sbjct: 351  ELRNQSPYFEQALYVASVLEEQPAGAAVTTVRARDPE---DSPVVYSM----VSLLDSRS 403

Query: 75   AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134
                        Q +F++D R+G + T ASLDRE +  +   V ATD + P     S T 
Sbjct: 404  ------------QSLFKVDSRTGVVTTSASLDRELMDVHYFRVVATDDSFPPR---SGTT 448

Query: 135  TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII-- 192
            T+ VN++D ND+ P F  + +  S+ E  +V     +  ++ATD D+G N+ I Y I   
Sbjct: 449  TLQVNVLDCNDHSPTFEAEQFEASIREGATV--GSTVITLRATDQDIGKNAEIEYGIEAV 506

Query: 193  ---GGNTQMQ----FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD---GGSPSRSNTTQ 242
                G  Q Q    F IDS SG +S   +LD E   SY L++ A D     S  R+ T  
Sbjct: 507  TDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATAS 566

Query: 243  LLINIRDVNDNAPRFYTSLFQESVSENVPIG---YSIVRVQAYDADEGVNAELTYTMTDK 299
            + + + D NDN P+F    +   V E+   G    ++  ++A DAD+G NA + Y +   
Sbjct: 567  VQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIG- 625

Query: 300  DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
               GN     +ID  SG V     LD E+   Y+L++ A DGG P RS T          
Sbjct: 626  ---GNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDA 682

Query: 360  XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG 419
                  F   Q++  + E+ P G  ++ + A D+DE        +       F +     
Sbjct: 683  NDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLAVDPR 742

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477
             G +   +PLD +++ R+   V A D G   +S ++ V I + D N+  P F    Y A+
Sbjct: 743  TGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEAN 802

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            V ED P GT V  V+ATD D   ++++ Y +++  +    A   Q        G IT  +
Sbjct: 803  VGEDQPPGTPVTTVTATDPDE--DSRLHYEITTGNTRGRFAITSQN-----GRGLITIAQ 855

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
             LD +    +LLTV A D G    SDT  V I++ D N+  P+F+   Y+A++ EDA VG
Sbjct: 856  SLDYKQEKRFLLTVAATDSG--GRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVG 913

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKD-REEGS---FVIDPASGVIRTNKALDRESVATH 653
            T+V  V ATD+DVG+N +I Y L+ +     GS   F I+P +G I TN  LDRE+ + +
Sbjct: 914  TTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGY 973

Query: 654  DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713
             L   A DGG P  S T  V I + D+ND+ P F+S      I E++ +GT++ ++ A D
Sbjct: 974  LLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASD 1033

Query: 714  PDEGPNAVVHYSIKGGD-DSNSFSLETRQGSDKAELVTMVDLDYESPRKKY--ELVIRAA 770
            PD G N  + Y +   D +  SF ++   G+    + T   LD ES    +   + +   
Sbjct: 1034 PDVGLNGRIKYLLSDRDIEDGSFVIDPTSGT----IRTNKGLDRESVAVFHLTAIAVDKG 1089

Query: 771  SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDAD--VTDKL 827
            SPPL + V V+I + DVND+ P     +I      +  PVG   G + A+D D  V   +
Sbjct: 1090 SPPLSSTVEVQIRLEDVNDSPPTFASDKITL-YVPENSPVGSVVGEIHAHDPDEGVNAVV 1148

Query: 828  QYRILSGNNANLILLNETTGS 848
             Y I+ G+++N   L    GS
Sbjct: 1149 HYSIIGGDDSNAFSLVTRPGS 1169



 Score =  358 bits (880), Expect = 1e-96
 Identities = 257/769 (33%), Positives = 391/769 (50%), Gaps = 52/769 (6%)

Query: 148  PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
            P F +  Y  SV E+        +  ++A D +         +++   +Q  F +DS +G
Sbjct: 357  PYFEQALYVASVLEEQPA--GAAVTTVRARDPEDSPVVYSMVSLLDSRSQSLFKVDSRTG 414

Query: 208  DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
             V+   +LD E +  +   + A D   P RS TT L +N+ D ND++P F    F+ S+ 
Sbjct: 415  VVTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIR 474

Query: 268  ENVPIGYSIVRVQAYDADEGVNAELTY---TMTD-KDYTGNVDLPI-TIDPRSGWVYTSG 322
            E   +G +++ ++A D D G NAE+ Y    +TD      + ++PI  ID RSG + T  
Sbjct: 475  EGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRS 534

Query: 323  QLDRETQAKYQLLVTATD---GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE 379
             LDRET   Y LLVTA D        R+ATA+              F    Y V++ ED+
Sbjct: 535  SLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQ 594

Query: 380  PPGT---PVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434
              GT    V  + ATDAD+ N   + Y I GGNT+ +FSI S +G   +++ +PLD++  
Sbjct: 595  WGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGD--VSLVKPLDYESV 652

Query: 435  RRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492
            R Y L + A D G   RS+T  + +N+ DAN+ AP F  + +  SV E+ P+G  ++ V 
Sbjct: 653  RSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQ 712

Query: 493  ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552
            A DSD G NA+ITYS+S    N  +A       ++P+TG + T K LDRE    +   V 
Sbjct: 713  AYDSDEGANAEITYSISERDDNFPLA-------VDPRTGWVQTIKPLDREEQGRFAFQVV 765

Query: 553  ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612
            A+DGGVP  S ++ V I+V DVNDN+P F  + Y AN+ ED   GT V+ V ATD D   
Sbjct: 766  AKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDE-- 823

Query: 613  NGRIHYELDPKDREEGSFVIDPAS--GVIRTNKALDRESVATHDLKAVAIDGGTPPQSST 670
            + R+HYE+       G F I   +  G+I   ++LD +      L   A D G   +S T
Sbjct: 824  DSRLHYEI-TTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSG--GRSDT 880

Query: 671  VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY-----S 725
              VHI I D N+  P+FE+   +  + E++P+GTT+  + A D D G NA + Y     S
Sbjct: 881  ATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEES 940

Query: 726  IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEI 782
            I G    + FS+  + G+    +VT   LD E+    Y L + A    +P L +   VEI
Sbjct: 941  INGLGSPDPFSINPQTGA----IVTNAPLDRET-TSGYLLTVTAKDGGNPSLSDTTDVEI 995

Query: 783  LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNA--N 838
             VTDVNDNAP  K      +  +D        +V A D DV    +++Y +LS  +    
Sbjct: 996  GVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKY-LLSDRDIEDG 1054

Query: 839  LILLNETTGSMTLSPQLN-TNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886
              +++ T+G++  +  L+  +V       ++V  G   + + +++ +RL
Sbjct: 1055 SFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRL 1103



 Score =  268 bits (656), Expect = 2e-69
 Identities = 203/656 (30%), Positives = 322/656 (49%), Gaps = 50/656 (7%)

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
           R++ + +P F  +L+  SV E  P G ++  V+A D ++   + + Y+M     + +  L
Sbjct: 350 RELRNQSPYFEQALYVASVLEEQPAGAAVTTVRARDPED---SPVVYSMVSLLDSRSQSL 406

Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
              +D R+G V TS  LDRE    +   V ATD   PPRS T T              F 
Sbjct: 407 -FKVDSRTGVVTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFE 465

Query: 368 PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHY---EITGGNTRGR------FSITS 416
             Q+E  + E    G+ V+TL ATD D  ++  + Y    +T G    +      F I S
Sbjct: 466 AEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDS 525

Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATD-----SGGRSDTAMVQINITDANNYAPVFEN 471
           ++  G+I+    LD +    Y L V+A D     S  R+ TA VQ+ + D N+  P F  
Sbjct: 526 RS--GVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSE 583

Query: 472 APYTASVFEDAPIGT---TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528
             YT  V ED   GT   TV  + ATD+D G NA I Y++          +   QF I+ 
Sbjct: 584 RTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIG-------GNTQSQFSIDS 636

Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588
            +G ++  K LD E++  Y L + A+DGG PS S+TT + ++V+D NDN P F    +  
Sbjct: 637 MSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQE 696

Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648
           +++E+  VG ++ +V A D+D G N  I Y +  +D +     +DP +G ++T K LDRE
Sbjct: 697 SVLENVPVGYNIIRVQAYDSDEGANAEITYSISERD-DNFPLAVDPRTGWVQTIKPLDRE 755

Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
                  + VA DGG PP+S++  V I ++D+ND+ P F        + E+ P GT +  
Sbjct: 756 EQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTT 815

Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVI 767
           + A DPDE  ++ +HY I  G+    F++ ++ G     L+T+   LDY+   K++ L +
Sbjct: 816 VTATDPDE--DSRLHYEITTGNTRGRFAITSQNGRG---LITIAQSLDYKQ-EKRFLLTV 869

Query: 768 RAASPPLWND-VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR-VPAYDADV-- 823
            A      +D   V I +TD N+ AP+ ++     + ++D  PVG     V A D+DV  
Sbjct: 870 AATDSGGRSDTATVHINITDANNFAPIFENAPYSASVFEDA-PVGTTVLVVSATDSDVGV 928

Query: 824 ----TDKLQYRILSG-NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN 874
               T  L    ++G  + +   +N  TG++  +  L+        + V+  DG N
Sbjct: 929 NAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGN 984



 Score =  231 bits (566), Expect = 2e-58
 Identities = 122/282 (43%), Positives = 186/282 (65%), Gaps = 31/282 (10%)

Query: 1791 RLYGADVVVAEGILLELMDYELRQAGLNLTHSQDKDYVRNLLKSTNTILNVEYEREWKRI 1850
            RLYGAD++V EG+L EL++YEL Q+GLNL+HSQDK +++NL+ + + IL+ +YE EW+R 
Sbjct: 2293 RLYGADLLVTEGLLQELINYELMQSGLNLSHSQDKYFIKNLVDAASVILDRKYEAEWRRA 2352

Query: 1851 RELTGHGAELLVQKFDEYIAVLAESQHDTYTSPFEIVTKDVVISVDTVTSESIYGFEPTQ 1910
             EL   G + LV  F++Y+ VLA SQHDTYTSPFEIV  ++ + +D VT+ES++G+EP Q
Sbjct: 2353 TELIQRGPDDLVDAFNKYLVVLARSQHDTYTSPFEIVQPNMALGLDIVTTESLFGYEPEQ 2412

Query: 1911 LNR------LNVDSYTTERVVALPDTSAFI-HSPIQAXXXXXXXXXXXXXXXXXXXVSFP 1963
            L+       L  +++TTE VV LPDTS F+ HS  Q                    +SFP
Sbjct: 2413 LSEYHRSKYLKPNAFTTESVV-LPDTSGFLQHSARQ-----------------RPVISFP 2454

Query: 1964 KYNNYVRSKNKFDKYTRVLLPLDLLGISNNNLQDITD-----TNYETRAVFGYVQYSRNS 2018
            KYNNY+  + KFD++T+VL+PL++LGI+     +I+      ++++ RA+  Y QY ++ 
Sbjct: 2455 KYNNYILDRRKFDQHTKVLVPLEMLGITPPESDEISQSGRRGSSHDHRAIVAYAQY-KDV 2513

Query: 2019 SQLMPLRMDDSVSLRWGVNITIGSPILQIAVFVPESIWTRET 2060
             QL+P   D++++ RWGV++ + +PIL + + VP     +ET
Sbjct: 2514 GQLLPDLYDETITRRWGVDVELATPILSLQILVPSMEREQET 2555



 Score =  200 bits (488), Expect = 4e-49
 Identities = 146/445 (32%), Positives = 225/445 (50%), Gaps = 34/445 (7%)

Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509
           +DT + +    +  N +P FE A Y ASV E+ P G  V  V A D +   ++ + YS+ 
Sbjct: 340 NDTDIARRVRRELRNQSPYFEQALYVASVLEEQPAGAAVTTVRARDPE---DSPVVYSMV 396

Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569
           S + + +       F ++ +TG +TT+  LDRE M  +   V A D   P  S TT +++
Sbjct: 397 SLLDSRS----QSLFKVDSRTGVVTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQV 452

Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD-------- 621
           +V+D ND+ P F+ + + A+I E A VG++V  + ATD D+G N  I Y ++        
Sbjct: 453 NVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGL 512

Query: 622 PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID---GGTPPQSSTVIVHIKIE 678
            +D+E   F ID  SGVI T  +LDRE+  ++ L   A D     +  +++T  V +K+ 
Sbjct: 513 AQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVL 572

Query: 679 DINDSPPVFESDCLTFYISENSPIGT---TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735
           D ND+ P F     T  + E+   GT   T+  IRA D D+G NA + Y+I GG+  + F
Sbjct: 573 DDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQF 632

Query: 736 SLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792
           S+++  G    ++  +  LDYES R  Y LVIRA    SP   N  ++ + V D NDNAP
Sbjct: 633 SIDSMSG----DVSLVKPLDYESVR-SYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAP 687

Query: 793 VMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTG-S 848
                Q    +  +  PVG    RV AYD+D     ++ Y I   ++   + ++  TG  
Sbjct: 688 RFYTSQ-FQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLAVDPRTGWV 746

Query: 849 MTLSPQLNTNVPKLATMEVSVTDGV 873
            T+ P       + A   V+   GV
Sbjct: 747 QTIKPLDREEQGRFAFQVVAKDGGV 771



 Score =  176 bits (429), Expect = 6e-42
 Identities = 80/167 (47%), Positives = 123/167 (73%), Gaps = 6/167 (3%)

Query: 2167 MYRSLSGIRLKKPIRLQIWLDINRETFGSRTNPQCVHWSTLRGSGEWSRVGCHTEI---D 2223
            +YRSL    L +PI+LQ+WLD++   FG R+NPQCV W++   + +W+R+GC TEI   D
Sbjct: 2713 VYRSLGSPHLAQPIKLQMWLDVDSARFGPRSNPQCVRWNSF--TNQWTRLGCQTEIPDFD 2770

Query: 2224 YDWSPYSEEPLLINCTCNHLSTFAVLVDEVDVEFIPEPSLLESVTSYTAFSISLPLLLTS 2283
             D++P +++ +L+NC+C H+S++AV+VD +D E IPEPSLL  +TSY+AF +SLPLLL  
Sbjct: 2771 GDFNPAAQQAILVNCSCTHISSYAVIVDVIDPEDIPEPSLLVQITSYSAFLVSLPLLLGV 2830

Query: 2284 WAALCLIRGGAATVSNSIHKHLIFSVFMAELLYLIALKARTSLVQNE 2330
              AL L+R G  T SN+IH++++  VF AELL+ + +++R  L+++E
Sbjct: 2831 LLALALLR-GQQTNSNTIHQNIVLCVFCAELLFFVGMQSRRQLLESE 2876



 Score =  142 bits (344), Expect = 1e-31
 Identities = 105/326 (32%), Positives = 150/326 (46%), Gaps = 18/326 (5%)

Query: 2330 EPVVWWVVIPXXXXXXXXXXXXXXXXXXXFTVRDHVTGFGNLRMLLAVSIVCLPLLCVAW 2389
            EPVVWW+V P                   FT++DHV GFGNLR LL +S+V LPL+ V W
Sbjct: 2957 EPVVWWLVGPIAGMSVVNLLILFVSVKAAFTLKDHVLGFGNLRTLLWLSVVSLPLMGVMW 3016

Query: 2390 ASALLLGSEAGGRRXXXXXXXXXXXXXXXIAASLGYIAFNVRVRDNLKRTVLRCMGKKVP 2449
              A+L  SE                    +   +GY   N RVR+NL+RT LRCMG+KVP
Sbjct: 3017 VLAVLAASE---HSQLLSLLLSGVVLLHALFCLIGYCIINKRVRENLQRTCLRCMGRKVP 3073

Query: 2450 LADTSVIISSSAHNLSQVNRSSLAYHSSTEPGRQMRNIGIXXXXXXXXXXXXXXXXXXXX 2509
            L D+S+++S+S+HN++   R S  + +S       RNIGI                    
Sbjct: 3074 LLDSSMVVSNSSHNVNAAARPS-NFLASGYDTTTRRNIGI--SASSTTSRSTAKTSSSPY 3130

Query: 2510 XDGQLRHXXXXXXXXXXXASDMPAYLRGFDSSLHTR-KDGERIAS--GSANSYLPNITEG 2566
             DGQLR            ASD P++LRGF+SS   R + GE   S     +S   + T+G
Sbjct: 3131 SDGQLRQ-TSTSTSNYNSASDAPSFLRGFESSTTGRSRGGEEKPSRRQRKDSDSGSETDG 3189

Query: 2567 APLAMSPRWPSHVREDQSRPEMGRWSQETGSDNEGANMGIATPSPNPLPNPDLTSDVYLN 2626
              L ++    SH  +D    +  R ++ +G+    A        PN   +   T+   LN
Sbjct: 3190 RSLELA---SSHSSDD----DESRTARSSGTHRSTAVSSTPAYLPNITEHVQATTPPELN 3242

Query: 2627 RHRLKPSILENVHDTYVASVDASRLP 2652
              +  P +  +V+    A   +S+LP
Sbjct: 3243 VVQ-SPQLFPSVNKPVYAPRWSSQLP 3267



 Score =  101 bits (241), Expect = 4e-19
 Identities = 97/307 (31%), Positives = 132/307 (42%), Gaps = 40/307 (13%)

Query: 2511 DGQLRHXXXXXXXXXXXASDMPAYLRGFDSSLHTRKDGERIASGSANSYLPNITEGAPLA 2570
            D + R             S  PAYL      +      E     S   + P++ +  P+ 
Sbjct: 3202 DDESRTARSSGTHRSTAVSSTPAYLPNITEHVQATTPPELNVVQSPQLF-PSVNK--PV- 3257

Query: 2571 MSPRWPSHVRED--QSRPEMGRWSQETGSDNEGAN-MGIATPSPNPLPNPDLTSDVYLNR 2627
             +PRW S + +   QS P +GRWSQ+TGSDNE  +     T SPNPLPNPDLT   YL +
Sbjct: 3258 YAPRWSSQLPDAYLQSPPNIGRWSQDTGSDNEHVHGQAKMTISPNPLPNPDLTDTSYLQQ 3317

Query: 2628 HRLK----PSILENVHDT---YVASVDASRLPLDNRYGVMEDELMYGVLPIDREKQMP-- 2678
            H  K    PSILEN+ D    Y  S+   R    ++YG  +    YG      EK  P  
Sbjct: 3318 HHNKINMPPSILENIRDAREGYEDSLYGRRGEYPDKYGSYKPPSHYG-----SEKDYPGG 3372

Query: 2679 YDPNYPISPTMYRLPGNPY-GSKTYLSSRTSDYGY----SPTKYMN----DTNVYGSRDF 2729
               +  I       P   Y     Y   RT   GY    S + Y++      ++YGS   
Sbjct: 3373 GSGSQTIGHMRSFHPDAAYLSDNIYDKQRTLGSGYLGAKSESPYLSKDRITPDIYGS--- 3429

Query: 2730 RDSGVSTRDHDGYPPRDFRDSGIATMLKNDY-QRKMDGHYGEYNDRMSEGSEKHHGHDKY 2788
            RD   S +    Y         + ++LKNDY Q++         DR+SEGS+K+  H   
Sbjct: 3430 RDGHYSLKRQPAYATDSLH--SVHSLLKNDYHQQQQQQQQHHLQDRLSEGSDKNGYH--- 3484

Query: 2789 LFPYTGK 2795
             FPYT +
Sbjct: 3485 -FPYTAE 3490


>UniRef50_Q7PPU8 Cluster: ENSANGP00000001238; n=2; Culicidae|Rep:
            ENSANGP00000001238 - Anopheles gambiae str. PEST
          Length = 3543

 Score = 1495 bits (3706), Expect = 0.0
 Identities = 727/1103 (65%), Positives = 870/1103 (78%), Gaps = 27/1103 (2%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            Q+NVLDCNDH+P FE +Q+ A+VREG S G+TV+T++ATDQDIGKNA++EY I  +  + 
Sbjct: 455  QVNVLDCNDHTPTFEAEQFHATVREGVSVGSTVITIRATDQDIGKNADIEYAITSILGEN 514

Query: 70   LNPEDAXXXXXXXXXXVQ-------DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122
                            V+         FRID RS  + TR++LDRE    YT++V ATD 
Sbjct: 515  QEQSGTAANGSNEGNPVEGDSNGSSQKFRIDARSCTISTRSALDREVSGMYTIMVTATDM 574

Query: 123  ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
            A+P S+R S+T T+ V I+DDNDNYPQFSE+TYTV V ED    +N VIA I+A+DAD G
Sbjct: 575  ATPQSERKSATTTVLVKILDDNDNYPQFSERTYTVQVREDQWANENNVIAHIQASDADQG 634

Query: 183  ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
             N+AIRYAIIGGNTQ QFSIDS+SGDVSLVK LDYE VRSYRLVIRAQDGGSPSRSNTTQ
Sbjct: 635  NNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYENVRSYRLVIRAQDGGSPSRSNTTQ 694

Query: 243  LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
            LL+N+ D NDNAPRFYTS FQE+V E+VP+GY+IVRVQAYD+DEG N+E+TY++ ++D  
Sbjct: 695  LLVNVLDANDNAPRFYTSQFQEAVLESVPVGYNIVRVQAYDSDEGANSEITYSIQNRDD- 753

Query: 303  GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
                +P+ +DPR+GW++T+  LDRE Q++Y   V A DGG PP+SA+ +           
Sbjct: 754  ---GMPLAVDPRTGWIHTTKALDREEQSRYSFQVVAVDGGIPPKSASTSVIVTIQDVNDN 810

Query: 363  XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422
               F P  YE  LAED+PPGTPV T+TATD DED+RLHYEIT GNTRGRF+ITSQNGRGL
Sbjct: 811  DPTFSPKYYEAMLAEDQPPGTPVTTVTATDPDEDSRLHYEITAGNTRGRFAITSQNGRGL 870

Query: 423  ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
            IT+AQPLD+KQERR+ LT++ATDSG R+DTA+V INITDANN+APVFENAPY+ASVFEDA
Sbjct: 871  ITIAQPLDYKQERRFALTITATDSGQRTDTAIVNINITDANNFAPVFENAPYSASVFEDA 930

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
            PIGTTVLVVSA+DSDVGINAQITY L+ E  N   A+  + F IN QTGAI TN  LDRE
Sbjct: 931  PIGTTVLVVSASDSDVGINAQITYLLNDESVNGLGAN--EPFTINAQTGAIITNAKLDRE 988

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
            + SGYLLTVTA+DGG PSLSDTTDVEISV DVNDN PVFK  LY A I EDAL+GTSV Q
Sbjct: 989  STSGYLLTVTAKDGGNPSLSDTTDVEISVTDVNDNAPVFKVPLYQATIPEDALIGTSVVQ 1048

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
            + ATD D+GLNGR+ Y L  KD +EGSFV+DP SGVIRTNK LDRES+  + L A+A D 
Sbjct: 1049 IAATDLDMGLNGRVKYALGQKDMDEGSFVVDPISGVIRTNKGLDRESIPVYHLTAIASDK 1108

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
            GTP  SS+V V I+++D+NDSPP F SD LT Y+ ENSP+G+ +GEI AHDPDEG NA+V
Sbjct: 1109 GTPTMSSSVEVQIRLDDVNDSPPTFASDKLTLYVPENSPVGSVVGEIYAHDPDEGVNAIV 1168

Query: 723  HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEI 782
            HYSI GGDDSNSFSL TR GSD+A+L+TM +LDYESPRK++EL+IRAASPPL NDV VEI
Sbjct: 1169 HYSIIGGDDSNSFSLVTRPGSDRAQLLTMTELDYESPRKRFELIIRAASPPLRNDVYVEI 1228

Query: 783  LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILL 842
            LVTDVNDNAPV++DFQ+IFNN++DCFP G  GR+PA+DADVTDKL YRILSGNNANL+ L
Sbjct: 1229 LVTDVNDNAPVLRDFQVIFNNFRDCFPSGVIGRIPAFDADVTDKLTYRILSGNNANLLRL 1288

Query: 843  NETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLND 902
            N +TG +TLSPQLNTNVPK ATMEVSVTDG+NE KA+MQL VRLITE+ML NS+TVRL++
Sbjct: 1289 NSSTGGLTLSPQLNTNVPKFATMEVSVTDGINEAKAIMQLIVRLITEDMLFNSVTVRLDE 1348

Query: 903  MTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGV 962
            MT E FLSPLL FF+DGLAAIIPCPKENI++FS+Q+D DV+G ILNVSFSARRPD     
Sbjct: 1349 MTEEAFLSPLLSFFLDGLAAIIPCPKENIFLFSIQEDIDVSGKILNVSFSARRPDVAF-- 1406

Query: 963  AGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNA 1022
                  +YS  +L+ER+YL+R  LARLATV+VLPFDDN+CV EPCLN+E+CL+VLKFGNA
Sbjct: 1407 ----EEYYSSQYLQERIYLNRAILARLATVRVLPFDDNLCVREPCLNYEQCLSVLKFGNA 1462

Query: 1023 SGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVD-GDGSICRSGSQCVA 1081
            SGF++SD+VLFRPI+PV +F C+CPEGFTG + E  L     EVD      C++G  C+ 
Sbjct: 1463 SGFIHSDTVLFRPIHPVNTFACKCPEGFTG-SREHYL--CDTEVDLCYSDPCQNGGSCM- 1518

Query: 1082 RREGGILCQGCSIDAAYTTAVCE 1104
            RREGG  C  C+    YT   CE
Sbjct: 1519 RREGGYSCV-CT--EQYTGVNCE 1538



 Score =  830 bits (2054), Expect = 0.0
 Identities = 389/761 (51%), Positives = 504/761 (66%), Gaps = 44/761 (5%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            ++C C E +TGVNCET +      +     +C  G  C+   +GG           YT  
Sbjct: 1524 YSCVCTEQYTGVNCETSIAGLKPCIS---EVCGDGYSCLTSGQGGHW-------PPYTKT 1573

Query: 1102 VCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVS 1161
             CEL +RSF  +SFLTFPG+++RHR +++LKFAT   SGLLLYNGRYNE+HDF+ALE+++
Sbjct: 1574 -CELMSRSFTRNSFLTFPGMRQRHRFNIRLKFATVRDSGLLLYNGRYNEQHDFIALEIIN 1632

Query: 1162 SEAGRGGGPGLRFSFSLGGGKSEITV--EGNVGDGSWHTVEIEYFNRTITMILDDCDKVL 1219
             +        + FSFSLG     +T+  +  V DG+WHTVE++YFNRT+ + LD+CD   
Sbjct: 1633 GK--------VVFSFSLGDKVETVTINQQRKVSDGNWHTVEVKYFNRTVLLSLDNCDTAT 1684

Query: 1220 SLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNK 1279
            +LAG    G ++ CAN T  VL  RC    E CHRF DLTGPLQIGGLP IP+ FQ+++ 
Sbjct: 1685 ALAG---LGERWNCANQTTLVLDRRCASLVEPCHRFFDLTGPLQIGGLPKIPAYFQIRSH 1741

Query: 1280 DFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLW-DTYICD 1338
             FVGCISD YID +++DL +Y+ADNGT+AGCP+K + C+S PC+NG  C + W + + CD
Sbjct: 1742 SFVGCISDLYIDQRYVDLGAYIADNGTVAGCPQKAASCASEPCFNGGTCREGWGEGWECD 1801

Query: 1339 CKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMSIQ-- 1396
            C +G TG  C +S   PWRF GDG+LSFNPLLRPIQLPWL A S+RTR+RD+FVM IQ  
Sbjct: 1802 CPDGFTGNACQESVALPWRFHGDGILSFNPLLRPIQLPWLTAFSLRTRKRDSFVMEIQVG 1861

Query: 1397 --------LKSGLLHYSYNGETMYLPMATLSDGAWHRIEIKWLGTDISVTVDYGLRTVLM 1448
                    L+ G+L Y YNGE + L  A L+DG WHR+EIKW+GT++S+TVDYG R+ ++
Sbjct: 1862 QNSSAVVSLRDGILQYLYNGEPLQLAGADLADGRWHRVEIKWMGTEVSLTVDYGQRSGVL 1921

Query: 1449 PMLANKIQGQYIGKILIGGLDTTAGL-LASDVGFFEGCIQDVRIGTAQSLLNRPTVRENV 1507
            P +  KIQG Y+G+I+IGGL+ T G         FEGCIQDVR+G  QS+L RPTVRENV
Sbjct: 1922 P-VTQKIQGLYVGRIVIGGLEGTIGQHYGGPSENFEGCIQDVRVGGVQSVLKRPTVRENV 1980

Query: 1508 RDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCG-AARCVPDQ 1566
             DGC S A C    CP  S CV++WD + C C  G VG +C   C + PC     C  D 
Sbjct: 1981 LDGCASNAKCPEG-CPEESVCVSNWDEAYCECLHGFVGGECKPVCTVKPCSDNGICRADT 2039

Query: 1567 -TPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGK 1625
               KGY C C    + +   C  + ++ CP GWWG  +CGPC C+V +GYHP+C+K  G+
Sbjct: 2040 VNTKGYRCECNSSLS-SGEYCENTVQQPCPAGWWGERSCGPCKCNVKQGYHPNCDKSTGQ 2098

Query: 1626 CHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVT 1685
            C+C+ENHY+P     CLPC+CY  GS   SC  ++GQC CR GVIGR CD+C+N YAEVT
Sbjct: 2099 CYCRENHYQPVNDTVCLPCECYTVGSYGKSCN-SSGQCECREGVIGRRCDSCSNPYAEVT 2157

Query: 1686 PNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSGRATRTCDETKDVPWQDPDM 1745
             N GCEVVYDGCP+S + G+WWPRT FG   + +CP  + G+ TR CD+ +   W  PDM
Sbjct: 2158 LN-GCEVVYDGCPKSHSAGLWWPRTAFGELAVENCPAPARGKGTRRCDQVQS-GWGAPDM 2215

Query: 1746 FNCTTATFYQLRKQLHKIETGELTMNTFVGVRVAADLSTAC 1786
            FNCT+  F  LRKQL +IE   L +NTF+ V+VAA L  AC
Sbjct: 2216 FNCTSEAFLDLRKQLSQIEVDGLELNTFISVKVAASLQQAC 2256



 Score =  331 bits (813), Expect = 2e-88
 Identities = 232/689 (33%), Positives = 346/689 (50%), Gaps = 62/689 (8%)

Query: 148  PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
            P F +  Y  SV E+     N  +  ++A D +         +++   +Q  F +DS +G
Sbjct: 361  PYFEQALYVASVLEEQPPGAN--VITVRARDPEDSPVVYSLVSLLDSRSQAMFKVDSRTG 418

Query: 208  DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
             V+   TLD E +  +   + A D   P RS TT L +N+ D ND+ P F    F  +V 
Sbjct: 419  VVTTSSTLDRELMDVHYFRVIATDDSFPPRSGTTTLQVNVLDCNDHTPTFEAEQFHATVR 478

Query: 268  ENVPIGYSIVRVQAYDADEGVNAELTYTMT-----DKDYTG------NVDLPI------- 309
            E V +G +++ ++A D D G NA++ Y +T     +++ +G      N   P+       
Sbjct: 479  EGVSVGSTVITIRATDQDIGKNADIEYAITSILGENQEQSGTAANGSNEGNPVEGDSNGS 538

Query: 310  ----TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP---RSATATXXXXXXXXXXX 362
                 ID RS  + T   LDRE    Y ++VTATD   P    +SAT T           
Sbjct: 539  SQKFRIDARSCTISTRSALDREVSGMYTIMVTATDMATPQSERKSATTTVLVKILDDNDN 598

Query: 363  XXXFMPGQYEVELAEDE--PPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQN 418
               F    Y V++ ED+       +  + A+DAD+ N   + Y I GGNT+ +FSI S +
Sbjct: 599  YPQFSERTYTVQVREDQWANENNVIAHIQASDADQGNNAAIRYAIIGGNTQSQFSIDSMS 658

Query: 419  GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTA 476
            G   +++ +PLD++  R Y L + A D G   RS+T  + +N+ DAN+ AP F  + +  
Sbjct: 659  GD--VSLVKPLDYENVRSYRLVIRAQDGGSPSRSNTTQLLVNVLDANDNAPRFYTSQFQE 716

Query: 477  SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
            +V E  P+G  ++ V A DSD G N++ITYS+ +      +A       ++P+TG I T 
Sbjct: 717  AVLESVPVGYNIVRVQAYDSDEGANSEITYSIQNRDDGMPLA-------VDPRTGWIHTT 769

Query: 537  KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
            K LDRE  S Y   V A DGG+P  S +T V +++ DVNDN+P F  + Y A + ED   
Sbjct: 770  KALDREEQSRYSFQVVAVDGGIPPKSASTSVIVTIQDVNDNDPTFSPKYYEAMLAEDQPP 829

Query: 597  GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS--GVIRTNKALDRESVATHD 654
            GT V+ V ATD D   + R+HYE+       G F I   +  G+I   + LD +      
Sbjct: 830  GTPVTTVTATDPDE--DSRLHYEI-TAGNTRGRFAITSQNGRGLITIAQPLDYKQERRFA 886

Query: 655  LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
            L   A D G   ++ T IV+I I D N+  PVFE+   +  + E++PIGTT+  + A D 
Sbjct: 887  LTITATDSG--QRTDTAIVNINITDANNFAPVFENAPYSASVFEDAPIGTTVLVVSASDS 944

Query: 715  DEGPNAVVHY-----SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
            D G NA + Y     S+ G   +  F++  + G+    ++T   LD ES    Y L + A
Sbjct: 945  DVGINAQITYLLNDESVNGLGANEPFTINAQTGA----IITNAKLDRES-TSGYLLTVTA 999

Query: 770  ---ASPPLWNDVRVEILVTDVNDNAPVMK 795
                +P L +   VEI VTDVNDNAPV K
Sbjct: 1000 KDGGNPSLSDTTDVEISVTDVNDNAPVFK 1028



 Score =  328 bits (806), Expect = 1e-87
 Identities = 271/877 (30%), Positives = 410/877 (46%), Gaps = 85/877 (9%)

Query: 15   DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
            +  + SP FE   Y ASV E    G  V+T++A D +   ++ V Y++       L+   
Sbjct: 355  ELRNQSPYFEQALYVASVLEEQPPGANVITVRARDPE---DSPVVYSL----VSLLDSRS 407

Query: 75   AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134
                        Q +F++D R+G + T ++LDRE +  +   V ATD + P     S T 
Sbjct: 408  ------------QAMFKVDSRTGVVTTSSTLDRELMDVHYFRVIATDDSFPPR---SGTT 452

Query: 135  TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA---I 191
            T+ VN++D ND+ P F  + +  +V E +SV     +  I+ATD D+G N+ I YA   I
Sbjct: 453  TLQVNVLDCNDHTPTFEAEQFHATVREGVSV--GSTVITIRATDQDIGKNADIEYAITSI 510

Query: 192  IGGN-----------------------TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIR 228
            +G N                       +  +F ID+ S  +S    LD E    Y +++ 
Sbjct: 511  LGENQEQSGTAANGSNEGNPVEGDSNGSSQKFRIDARSCTISTRSALDREVSGMYTIMVT 570

Query: 229  AQDGGSPS---RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS--IVRVQAYD 283
            A D  +P    +S TT +L+ I D NDN P+F    +   V E+     +  I  +QA D
Sbjct: 571  ATDMATPQSERKSATTTVLVKILDDNDNYPQFSERTYTVQVREDQWANENNVIAHIQASD 630

Query: 284  ADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD 343
            AD+G NA + Y +      GN     +ID  SG V     LD E    Y+L++ A DGG 
Sbjct: 631  ADQGNNAAIRYAIIG----GNTQSQFSIDSMSGDVSLVKPLDYENVRSYRLVIRAQDGGS 686

Query: 344  PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEI 403
            P RS T                F   Q++  + E  P G  +V + A D+DE        
Sbjct: 687  PSRSNTTQLLVNVLDANDNAPRFYTSQFQEAVLESVPVGYNIVRVQAYDSDEGANSEITY 746

Query: 404  TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITD 461
            +  N      +      G I   + LD +++ RY   V A D G   +S +  V + I D
Sbjct: 747  SIQNRDDGMPLAVDPRTGWIHTTKALDREEQSRYSFQVVAVDGGIPPKSASTSVIVTIQD 806

Query: 462  ANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521
             N+  P F    Y A + ED P GT V  V+ATD D   ++++ Y +++  +    A   
Sbjct: 807  VNDNDPTFSPKYYEAMLAEDQPPGTPVTTVTATDPDE--DSRLHYEITAGNTRGRFAITS 864

Query: 522  QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581
            Q        G IT  + LD +    + LT+TA D G    +DT  V I++ D N+  PVF
Sbjct: 865  QN-----GRGLITIAQPLDYKQERRFALTITATDSG--QRTDTAIVNINITDANNFAPVF 917

Query: 582  KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD----REEGSFVIDPASG 637
            +   Y+A++ EDA +GT+V  V A+D+DVG+N +I Y L+ +          F I+  +G
Sbjct: 918  ENAPYSASVFEDAPIGTTVLVVSASDSDVGINAQITYLLNDESVNGLGANEPFTINAQTG 977

Query: 638  VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697
             I TN  LDRES + + L   A DGG P  S T  V I + D+ND+ PVF+       I 
Sbjct: 978  AIITNAKLDRESTSGYLLTVTAKDGGNPSLSDTTDVEISVTDVNDNAPVFKVPLYQATIP 1037

Query: 698  ENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD-DSNSFSLETRQGSDKAELVTMVDLDY 756
            E++ IGT++ +I A D D G N  V Y++   D D  SF ++   G     + T   LD 
Sbjct: 1038 EDALIGTSVVQIAATDLDMGLNGRVKYALGQKDMDEGSFVVDPISG----VIRTNKGLDR 1093

Query: 757  ESPRKKYELVIRA--ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-F 813
            ES    +   I +   +P + + V V+I + DVND+ P     ++      +  PVG   
Sbjct: 1094 ESIPVYHLTAIASDKGTPTMSSSVEVQIRLDDVNDSPPTFASDKLTL-YVPENSPVGSVV 1152

Query: 814  GRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGS 848
            G + A+D D  V   + Y I+ G+++N   L    GS
Sbjct: 1153 GEIYAHDPDEGVNAIVHYSIIGGDDSNSFSLVTRPGS 1189



 Score =  253 bits (619), Expect = 6e-65
 Identities = 200/671 (29%), Positives = 316/671 (47%), Gaps = 64/671 (9%)

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            R++ + +P F  +L+  SV E  P G +++ V+A D ++   + + Y++           
Sbjct: 354  RELRNQSPYFEQALYVASVLEEQPPGANVITVRARDPED---SPVVYSLVSL-LDSRSQA 409

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
               +D R+G V TS  LDRE    +   V ATD   PPRS T T              F 
Sbjct: 410  MFKVDSRTGVVTTSSTLDRELMDVHYFRVIATDDSFPPRSGTTTLQVNVLDCNDHTPTFE 469

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEIT--------------GGNTRGR 411
              Q+   + E    G+ V+T+ ATD D  ++  + Y IT               G+  G 
Sbjct: 470  AEQFHATVREGVSVGSTVITIRATDQDIGKNADIEYAITSILGENQEQSGTAANGSNEGN 529

Query: 412  FSITSQNGRG----------LITVAQPLDFKQERRYVLTVSATD-----SGGRSDTAMVQ 456
                  NG             I+    LD +    Y + V+ATD     S  +S T  V 
Sbjct: 530  PVEGDSNGSSQKFRIDARSCTISTRSALDREVSGMYTIMVTATDMATPQSERKSATTTVL 589

Query: 457  INITDANNYAPVFENAPYTASVFED--APIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
            + I D N+  P F    YT  V ED  A     +  + A+D+D G NA I Y++      
Sbjct: 590  VKILDDNDNYPQFSERTYTVQVREDQWANENNVIAHIQASDADQGNNAAIRYAIIG---- 645

Query: 515  EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
                +   QF I+  +G ++  K LD E +  Y L + A+DGG PS S+TT + ++V+D 
Sbjct: 646  ---GNTQSQFSIDSMSGDVSLVKPLDYENVRSYRLVIRAQDGGSPSRSNTTQLLVNVLDA 702

Query: 575  NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG-SFVID 633
            NDN P F    +   ++E   VG ++ +V A D+D G N  I Y +  ++R++G    +D
Sbjct: 703  NDNAPRFYTSQFQEAVLESVPVGYNIVRVQAYDSDEGANSEITYSI--QNRDDGMPLAVD 760

Query: 634  PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693
            P +G I T KALDRE  + +  + VA+DGG PP+S++  V + I+D+ND+ P F      
Sbjct: 761  PRTGWIHTTKALDREEQSRYSFQVVAVDGGIPPKSASTSVIVTIQDVNDNDPTFSPKYYE 820

Query: 694  FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753
              ++E+ P GT +  + A DPDE  ++ +HY I  G+    F++ ++ G     L+T+  
Sbjct: 821  AMLAEDQPPGTPVTTVTATDPDE--DSRLHYEITAGNTRGRFAITSQNGRG---LITIAQ 875

Query: 754  -LDYESPRKKYELVIRAASPPLWNDVR-VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811
             LDY+  R ++ L I A       D   V I +TD N+ APV ++     + ++D  P+G
Sbjct: 876  PLDYKQER-RFALTITATDSGQRTDTAIVNINITDANNFAPVFENAPYSASVFEDA-PIG 933

Query: 812  PFGR-VPAYDADV------TDKLQYRILSGNNAN-LILLNETTGSMTLSPQLNTNVPKLA 863
                 V A D+DV      T  L    ++G  AN    +N  TG++  + +L+       
Sbjct: 934  TTVLVVSASDSDVGINAQITYLLNDESVNGLGANEPFTINAQTGAIITNAKLDRESTSGY 993

Query: 864  TMEVSVTDGVN 874
             + V+  DG N
Sbjct: 994  LLTVTAKDGGN 1004



 Score =  229 bits (560), Expect = 8e-58
 Identities = 119/273 (43%), Positives = 179/273 (65%), Gaps = 28/273 (10%)

Query: 1791 RLYGADVVVAEGILLELMDYELRQAGLNLTHSQDKDYVRNLLKSTNTILNVEYEREWKRI 1850
            +LYGAD+++ + +L ELM YE  Q GLNL+HSQDK YVRNL++S   IL+  Y  EWKR+
Sbjct: 2317 KLYGADLLITDRLLHELMRYEAYQHGLNLSHSQDKHYVRNLVESAGEILDRRYASEWKRV 2376

Query: 1851 RELTGHGAELLVQKFDEYIAVLAESQHDTYTSPFEIVTKDVVISVDTVTSESIYGFEPTQ 1910
            ++LTG G + LV  F++Y+ VLA SQHDTYT+PFEIV K++V+ +D VT+ES++G+E   
Sbjct: 2377 QDLTGRGPDDLVDAFNQYMIVLARSQHDTYTNPFEIVHKNMVLGMDIVTTESLFGYESQM 2436

Query: 1911 LNRL---------NVDSYTTERVVALPDTSAFI-HSPIQAXXXXXXXXXXXXXXXXXXXV 1960
            + +          ++  +  E V+ LPDTS+F+ +SP Q                    +
Sbjct: 2437 VKQQQFKQAKGHPDLHGHPAETVI-LPDTSSFLQNSPKQ----------------KQPLI 2479

Query: 1961 SFPKYNNYVRSKNKFDKYTRVLLPLDLLGISNNNLQDITDTNYETRAVFGYVQYSRNSSQ 2020
            SFPKYNNY++ ++KFD+ T+VL+PLD+LGI+  +  ++ +   E RA+F Y QY +++ +
Sbjct: 2480 SFPKYNNYIQDRSKFDRSTKVLVPLDMLGITAPDKNEVVNQIAEHRAIFTYAQY-KDAGE 2538

Query: 2021 LMPLRMDDSVSLRWGVNITIGSPILQIAVFVPE 2053
            L P   D++V+ RWGV + I S +L IA+  PE
Sbjct: 2539 LFPTNFDETVTRRWGVEMQIASSVLSIAIVTPE 2571



 Score =  182 bits (442), Expect = 2e-43
 Identities = 142/459 (30%), Positives = 218/459 (47%), Gaps = 49/459 (10%)

Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509
           +DT + +    +  N +P FE A Y ASV E+ P G  V+ V A D +   ++ + YSL 
Sbjct: 344 NDTDIAKRVRRELRNQSPYFEQALYVASVLEEQPPGANVITVRARDPE---DSPVVYSLV 400

Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569
           S + + + A     F ++ +TG +TT+  LDRE M  +   V A D   P  S TT +++
Sbjct: 401 SLLDSRSQA----MFKVDSRTGVVTTSSTLDRELMDVHYFRVIATDDSFPPRSGTTTLQV 456

Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE----LDPKDR 625
           +V+D ND+ P F+ + + A + E   VG++V  + ATD D+G N  I Y     L     
Sbjct: 457 NVLDCNDHTPTFEAEQFHATVREGVSVGSTVITIRATDQDIGKNADIEYAITSILGENQE 516

Query: 626 EEGS---------------------FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
           + G+                     F ID  S  I T  ALDRE    + +   A D  T
Sbjct: 517 QSGTAANGSNEGNPVEGDSNGSSQKFRIDARSCTISTRSALDREVSGMYTIMVTATDMAT 576

Query: 665 PP---QSSTVIVHIKIEDINDSPPVFESDCLTFYISEN--SPIGTTIGEIRAHDPDEGPN 719
           P    +S+T  V +KI D ND+ P F     T  + E+  +     I  I+A D D+G N
Sbjct: 577 PQSERKSATTTVLVKILDDNDNYPQFSERTYTVQVREDQWANENNVIAHIQASDADQGNN 636

Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776
           A + Y+I GG+  + FS+++  G    ++  +  LDYE+ R  Y LVIRA    SP   N
Sbjct: 637 AAIRYAIIGGNTQSQFSIDSMSG----DVSLVKPLDYENVR-SYRLVIRAQDGGSPSRSN 691

Query: 777 DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILS 833
             ++ + V D NDNAP     Q       +  PVG    RV AYD+D     ++ Y I +
Sbjct: 692 TTQLLVNVLDANDNAPRFYTSQ-FQEAVLESVPVGYNIVRVQAYDSDEGANSEITYSIQN 750

Query: 834 GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            ++   + ++  TG +  +  L+       + +V   DG
Sbjct: 751 RDDGMPLAVDPRTGWIHTTKALDREEQSRYSFQVVAVDG 789



 Score =  166 bits (404), Expect = 7e-39
 Identities = 87/189 (46%), Positives = 128/189 (67%), Gaps = 13/189 (6%)

Query: 2143 DGPKVMALVMDGETRSNATGVGKKMYRSLSGIRLKKPIRLQIWLDINRETFGSRTNPQCV 2202
            DG    ++ MD  +R+N   +G+          LK+ I+LQ+WL+I R  F SR+NPQCV
Sbjct: 2696 DGGIPESVEMDSASRTNYVPLGQP--------HLKQAIKLQMWLNIPRNRFVSRSNPQCV 2747

Query: 2203 HWSTLRGSGEWSRVGCHTEI-DYDWSPYSEEPLLINCTCNHLSTFAVLVDEVDVEFIPEP 2261
             W+T   +  W+R+GC TEI +Y+   +++  +++NCTCN L+T+AVLVD +D E IPEP
Sbjct: 2748 RWNT--HANLWTRIGCQTEIPNYEMIGHNDT-IVVNCTCNQLATYAVLVDIIDPEDIPEP 2804

Query: 2262 SLLESVTSYTAFSISLPLLLTSWAALCLIRGGAATVSNSIHKHLIFSVFMAELLYLIALK 2321
            SLL  +TSY+AF +SLP+L     +L L+R G  T SNSIH++L+F +F AELL+ +A++
Sbjct: 2805 SLLVQITSYSAFLLSLPILFAVIVSLALLR-GLQTNSNSIHQNLLFCIFTAELLFFVAIQ 2863

Query: 2322 ARTSLVQNE 2330
            AR  L+ NE
Sbjct: 2864 ARRDLLDNE 2872



 Score =  120 bits (289), Expect = 6e-25
 Identities = 73/232 (31%), Positives = 102/232 (43%), Gaps = 8/232 (3%)

Query: 2330 EPVVWWVVIPXXXXXXXXXXXXXXXXXXXFTVRDHVTGFGNLRMLLAVSIVCLPLLCVAW 2389
            E V+WW+V P                   FT++DHV GFGNLR LL +S+V LPLL + W
Sbjct: 2953 ESVIWWMVGPIAIVSVFDLFILFLSVKAAFTIKDHVLGFGNLRTLLWLSVVSLPLLGIMW 3012

Query: 2390 ASALLLGSEAGGRRXXXXXXXXXXXXXXXIAASLGYIAFNVRVRDNLKRTVLRCMGKKVP 2449
              A+L  SE                    + + +GY   N RVR+NL    LRCMG+KVP
Sbjct: 3013 VLAVLSASE---NSQLLNMLLSAVVIMHSLFSIIGYCIINKRVRENLHNAFLRCMGRKVP 3069

Query: 2450 LADTSVIISSSAHNLSQVNRSSLAYHSSTEPGRQMRNIGIXXXXXXXXXXXXXXXXXXXX 2509
            L ++S+ IS+S+ N+        A  S  +     RNIGI                    
Sbjct: 3070 LLESSIAISNSSQNVGSPKTPGFAGSSGGQYDTARRNIGI-STSSTTSRSTAKTSSSPYR 3128

Query: 2510 XDGQLRHXXXXXXXXXXXASDMPAYLRGF--DSSLHTRKDGERIASGSANSY 2559
             DGQ RH           +  + +Y+RG   +S+L   K+G +   G   S+
Sbjct: 3129 SDGQFRH--TSTSTSNYNSDGVASYMRGHYEESALRKIKNGGQGRDGERRSH 3178



 Score = 95.9 bits (228), Expect = 1e-17
 Identities = 53/168 (31%), Positives = 87/168 (51%), Gaps = 5/168 (2%)

Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620
           L+DT   +    ++ +  P F+Q LY A+++E+   G +V  V A D +   +  + Y L
Sbjct: 343 LNDTDIAKRVRRELRNQSPYFEQALYVASVLEEQPPGANVITVRARDPE---DSPVVYSL 399

Query: 621 DP--KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678
                 R +  F +D  +GV+ T+  LDRE +  H  + +A D   PP+S T  + + + 
Sbjct: 400 VSLLDSRSQAMFKVDSRTGVVTTSSTLDRELMDVHYFRVIATDDSFPPRSGTTTLQVNVL 459

Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
           D ND  P FE++     + E   +G+T+  IRA D D G NA + Y+I
Sbjct: 460 DCNDHTPTFEAEQFHATVREGVSVGSTVITIRATDQDIGKNADIEYAI 507



 Score = 91.5 bits (217), Expect = 3e-16
 Identities = 83/265 (31%), Positives = 113/265 (42%), Gaps = 33/265 (12%)

Query: 2556 ANSYLPNITEGAP-------LAMSP---------RWPSHVREDQSRPEMGRWSQETGSDN 2599
            + SYLPNITE          +  SP         RWP+    +   P  GRWSQET SDN
Sbjct: 3225 STSYLPNITEHVATTPPELHVVQSPQLFPNVTPTRWPNQNANNYMPPGNGRWSQETASDN 3284

Query: 2600 EGANMGIATPSPNPLPNPDLTSDVYL--NRHRLKPSILENVHDTYVASVDASRLPLDNRY 2657
            E A+   +  +   LPNPD+T   YL  NR  + PSILEN+ + Y      + L  D  Y
Sbjct: 3285 E-AHPHKSPTNGGSLPNPDITETSYLHQNRMNMPPSILENIQENYNIGYSNTDLHSDRNY 3343

Query: 2658 GVMEDELMYGVLPIDREKQMPYDPNYPISPTMYRLPGNPYGSKTYLSSRTSDYGYSPTKY 2717
                +   Y V P D  K+             Y+   NPY  K  L  R+   GY  +  
Sbjct: 3344 SNYGNADNY-VPPADYAKRHTGSMQVINHMRAYQ-HENPYALKESLYERSRTLGYGTSAG 3401

Query: 2718 MNDTNVYGSRDFRDSGVSTRDHDGYPPRDFRDSGIATMLKNDYQRKMDGHY-------GE 2770
              ++  +                      F+ S + ++LKNDYQ++    Y       G 
Sbjct: 3402 GAESPYHAGHPLTAPNDLYSPPGAIHGMSFK-SSVQSLLKNDYQQQQRQQYKHHQTGNGG 3460

Query: 2771 YNDRMSEGSEKHHGHDKYLFPYTGK 2795
             +DRMSEGS+K    + Y FPYT +
Sbjct: 3461 ESDRMSEGSDK----NPYNFPYTAE 3481



 Score = 42.7 bits (96), Expect = 0.14
 Identities = 37/160 (23%), Positives = 62/160 (38%), Gaps = 7/160 (4%)

Query: 638 VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697
           +I  N   DR+ +   D +   +        + +   ++ E  N SP  FE       + 
Sbjct: 315 IITYNVRCDRKDIIDADHRLKIVYHHQELNDTDIAKRVRRELRNQSP-YFEQALYVASVL 373

Query: 698 ENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757
           E  P G  +  +RA DP++ P      S+        F +++R G     + T   LD E
Sbjct: 374 EEQPPGANVITVRARDPEDSPVVYSLVSLLDSRSQAMFKVDSRTG----VVTTSSTLDRE 429

Query: 758 SPRKKYELVIRA--ASPPLWNDVRVEILVTDVNDNAPVMK 795
                Y  VI    + PP      +++ V D ND+ P  +
Sbjct: 430 LMDVHYFRVIATDDSFPPRSGTTTLQVNVLDCNDHTPTFE 469



 Score = 37.1 bits (82), Expect = 7.0
 Identities = 16/42 (38%), Positives = 19/42 (45%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADS 1351
            C  +   C S PC NG  C      Y C C E +TG +C  S
Sbjct: 1499 CDTEVDLCYSDPCQNGGSCMRREGGYSCVCTEQYTGVNCETS 1540


>UniRef50_UPI0000DB794E Cluster: PREDICTED: similar to
            Protocadherin-like wing polarity protein stan precursor
            (Protein starry night) (Protein flamingo); n=2;
            Apocrita|Rep: PREDICTED: similar to Protocadherin-like
            wing polarity protein stan precursor (Protein starry
            night) (Protein flamingo) - Apis mellifera
          Length = 3166

 Score = 1433 bits (3550), Expect = 0.0
 Identities = 700/1088 (64%), Positives = 856/1088 (78%), Gaps = 31/1088 (2%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD- 68
            Q+NVLD NDH+P FE  + EAS+REG   G+TV+T+KATDQD G+NAEVEY+I   T+  
Sbjct: 353  QVNVLDTNDHAPSFEWPEEEASIREGVPVGSTVVTVKATDQDAGRNAEVEYSILSTTSSS 412

Query: 69   -TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
             T N EDA             +FRID R+G + TR  LDREK   YTV++  +DQA+P S
Sbjct: 413  GTANTEDAL------------IFRIDPRTGVVTTRTPLDREKTEVYTVILSVSDQATPPS 460

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
             R ++ AT+ V ++DDNDNYPQF+E+TY+  + ED+  T NPVIA+I+ATDAD G N+A+
Sbjct: 461  ARKTANATLVVRVLDDNDNYPQFTERTYSAWIPEDLDYTANPVIARIRATDADSGNNAAV 520

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            RYAIIGGNTQ  FSIDS+ GDV+LVK LDYE  RSY++VIRAQDGGSP+RSNTTQLL+++
Sbjct: 521  RYAIIGGNTQNTFSIDSMVGDVALVKPLDYESTRSYKIVIRAQDGGSPARSNTTQLLVHV 580

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG--NV 305
             DVNDNAPRFYTS FQESVSENVP+GYSI+R+QAYDADEG NA++ YT+  +D+TG    
Sbjct: 581  GDVNDNAPRFYTSHFQESVSENVPVGYSILRIQAYDADEGANAQIKYTIGARDFTGASTE 640

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
            + PIT++  +GW+YT+ QLDRE  ++YQ  V A D G+  +SA+AT              
Sbjct: 641  NFPITVNTETGWLYTTKQLDREQCSRYQFTVIAADSGEISKSASATVILTVTDVNDNDPY 700

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV 425
            F P  YE  ++ED+PPGTPV ++TATD DED R+HYEIT GNTRGRF+I SQNGRGLIT+
Sbjct: 701  FDPKNYESVVSEDDPPGTPVTSVTATDPDEDARIHYEITAGNTRGRFAIASQNGRGLITI 760

Query: 426  AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
            AQPLD+KQE+R+VLTV+A+DSGGR+DTA+V +NI+DANN++PVFENAPY+ SVFEDAPIG
Sbjct: 761  AQPLDYKQEKRFVLTVTASDSGGRTDTALVYVNISDANNFSPVFENAPYSVSVFEDAPIG 820

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
            TTVLVVSATDSDVG NAQ+TYSL ++  ++  +    +F+INPQTGAITT K LDRE + 
Sbjct: 821  TTVLVVSATDSDVGKNAQVTYSLDTDNGDQTAS----EFIINPQTGAITTTKPLDREIVP 876

Query: 546  GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
             YLLTVTARDGG+P LSDTTDVEISV DVNDN PVF+   Y  +I ED LVGTSV +V A
Sbjct: 877  AYLLTVTARDGGIPPLSDTTDVEISVTDVNDNAPVFEAPQYQGSIPEDVLVGTSVLRVSA 936

Query: 606  TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
            TDAD  LNGR+ Y L+  D  +G+F +D  +G+IRT K LDRESVA + LKAVA+D G+P
Sbjct: 937  TDADTDLNGRVRYALE--DDGDGAFAVDSTTGIIRTAKPLDRESVAKYILKAVAMDRGSP 994

Query: 666  PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
              S+ V V IKIED+NDSPP FE+D +  YI+ENSPIG+T+GEI AHDPDEGPNAVV YS
Sbjct: 995  SLSTVVPVTIKIEDVNDSPPAFENDKIILYIAENSPIGSTVGEIYAHDPDEGPNAVVQYS 1054

Query: 726  IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVT 785
            + GG+DSNSF+L  R G+D+AEL+T+ +LDYESP+KK+ELV+RAASPPL +D  V+ILVT
Sbjct: 1055 VIGGEDSNSFALNIRPGADRAELITLEELDYESPKKKFELVVRAASPPLRSDALVQILVT 1114

Query: 786  DVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNET 845
            DVNDNAPV+KDFQIIFNN+KD FP  P G++PA DADVTDKL Y IL+GNNANLI LN T
Sbjct: 1115 DVNDNAPVLKDFQIIFNNFKDFFPTAPIGKIPAIDADVTDKLTYTILAGNNANLIDLNRT 1174

Query: 846  TGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTA 905
            +G + LSPQLNTNVP++ATMEVSVTDG+NE+KA M LSVRLIT++MLLNSITVRL+DMTA
Sbjct: 1175 SGEIRLSPQLNTNVPRVATMEVSVTDGINEVKATMTLSVRLITDKMLLNSITVRLDDMTA 1234

Query: 906  EQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGD 965
            E FLSPLLG+F+DGLAAIIPCP+ENI++FS+Q+D +V G ILNVSFSAR+   E GV  +
Sbjct: 1235 EAFLSPLLGYFLDGLAAIIPCPRENIFLFSIQEDANVNGKILNVSFSARK--VEPGVTDE 1292

Query: 966  PSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGF 1025
                YSP  L+ERVYL+R  LARLATV VLPFDDN+CV EPCLNFEECLTVLKFGNASGF
Sbjct: 1293 ---FYSPQFLQERVYLNRGILARLATVTVLPFDDNLCVREPCLNFEECLTVLKFGNASGF 1349

Query: 1026 VNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG 1085
             +SD+VLFRPIYPVT+F C+C  GFTG + E+ L      +      C +G  C  RREG
Sbjct: 1350 ASSDTVLFRPIYPVTTFACRCARGFTG-SKESYLCDTEVNLCYSNP-CVNGGTCY-RREG 1406

Query: 1086 GILCQGCS 1093
            G  C  CS
Sbjct: 1407 GYAC-SCS 1413



 Score = 1054 bits (2609), Expect = 0.0
 Identities = 497/1035 (48%), Positives = 665/1035 (64%), Gaps = 60/1035 (5%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYT-T 1100
            + C C   F G NCE  L K SC       IC+ GSQC  +  GG  C+GC +      T
Sbjct: 1408 YACSCSPEFGGENCEISLDKNSCAP----GICKGGSQCTMKTTGGFTCEGCPVTTLENVT 1463

Query: 1101 AVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELV 1160
             +CEL+ARSF  ++FLTF  L++RHR+ +KL+FAT+  +GLLLYNGRYNE+HDF+ALE++
Sbjct: 1464 PLCELKARSFGPATFLTFASLRQRHRLQIKLRFATEAANGLLLYNGRYNEKHDFIALEII 1523

Query: 1161 SSEAGRGGGPGLRFSFSLGGG--KSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKV 1218
             SE        ++FSFSLG    ++  ++ G V DG WH VE+ Y N+T+T+ LD+CD  
Sbjct: 1524 DSE--------VQFSFSLGDEITRTSASIPGGVSDGQWHEVEVSYINKTVTISLDNCDVA 1575

Query: 1219 LSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKN 1278
            L+L      G K++CA  + +VL  RC I TETCHRFLDLTGPLQ+GGLP IPSSF+++N
Sbjct: 1576 LALEYGDRLGRKWSCAGRSEQVLEERCSIVTETCHRFLDLTGPLQLGGLPAIPSSFRIRN 1635

Query: 1279 KDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICD 1338
            KDFVGC+SD YIDH FIDLNS+VADNGT  GCPEK S CSS+PC N  +C ++W  ++C+
Sbjct: 1636 KDFVGCVSDLYIDHIFIDLNSFVADNGTNPGCPEKVSFCSSSPCKNNGKCREIWAGFVCE 1695

Query: 1339 CKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMS---- 1394
            C+E   G  CAD  G PW F GDGM+SFNPLLRPIQLPWL ALS+RTR R AFVMS    
Sbjct: 1696 CEENFAGPTCADEVGKPWNFHGDGMISFNPLLRPIQLPWLTALSLRTRSRQAFVMSVQIG 1755

Query: 1395 ------IQLKSGLLHYSYNGETMYLPMATLSDGAWHRIEIKWLGTDISVTVDYGLRTVLM 1448
                  IQ++ G L    +G  +   +  ++DG WHR+EI W    +S+ +DY  R +L 
Sbjct: 1756 QNSSALIQIREGKLVALLDGADIIQTLNDIADGEWHRVEIVWQSGHVSLDIDYRSRPILS 1815

Query: 1449 PMLANKIQGQYIGKILIGGLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRPTVRENVR 1508
             + A K+QG YIG+IL+GG + +  +   ++ +F+GC+QD+RIG+ QS+L RPTV+ENV 
Sbjct: 1816 SLPA-KLQGLYIGRILVGGPEQSMNI---ELPYFDGCLQDIRIGSNQSVLLRPTVQENVA 1871

Query: 1509 DGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPC-GAARCVPDQT 1567
             GC S A+C +  CP  S CV  W +  C C  GRVG  C   C+L PC  +  C+ D T
Sbjct: 1872 TGCSSEAECNVD-CPEASICVPKWKAGECVCATGRVGRNCERVCDLNPCNNSGACIEDAT 1930

Query: 1568 P-KGYSCAC-EPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGK 1625
              +GY C C  P Y  + + C     + CP  WWG   CGPC CD ++GY P CNK  G+
Sbjct: 1931 SRRGYRCECNSPEY--SGNYCEIKADQPCPATWWGSPVCGPCHCDESKGYDPACNKTTGE 1988

Query: 1626 CHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVT 1685
            C+CKENHY+P G  EC+PC+CYA GS    C+  TGQC CR GVIGR+C AC N YAEVT
Sbjct: 1989 CYCKENHYQPSGKKECIPCECYATGSFGPRCDTETGQCRCRVGVIGRSCTACPNPYAEVT 2048

Query: 1686 PNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSGRATRTCDETKDVPWQDPDM 1745
               GCEVVYDGCPRS++ G+WWPRTKFG+  + DCP  + G+ +R+CD+ K   WQ+PD+
Sbjct: 2049 LR-GCEVVYDGCPRSYSEGLWWPRTKFGMIAVEDCPDMAEGKTSRSCDD-KLGGWQEPDL 2106

Query: 1746 FNCTTATFYQLRKQLHKIETGELTMNTFVGVRVAADLSTACANTPRLYGADVVVAEGILL 1805
            FNCT+  F + R QL  +ET ELT+NT+V V++A D+  A   T  LYGAD++VAE +L+
Sbjct: 2107 FNCTSEAFIEQRHQLAALETKELTLNTYVAVKIAKDVYRAVNVTKELYGADLLVAESLLV 2166

Query: 1806 ELMDYELRQAGLNLTHSQDKDYVRNLLKSTNTILNVEYEREWKRIRELTGHGAELLVQKF 1865
             L+ YE    GLNLTHSQDKDYV  L+   + IL  +Y  +W RI  L G   + ++   
Sbjct: 2167 ALLQYEESLVGLNLTHSQDKDYVSYLVGIASNILKSKYLEKWSRIETLNGDTPDKVLNAM 2226

Query: 1866 DEYIAVLAESQHDTYTSPFEIVTKDVVISVDTVTSESIYGFEPTQL----NRLNVDSYTT 1921
              Y+  L  SQHDT+T+PFEIV  +VV+ +D VTSES++G+E  +     +         
Sbjct: 2227 GNYLKTLTASQHDTFTNPFEIVDINVVLGLDVVTSESLFGYETAEYTEDPSASTARPTEA 2286

Query: 1922 ERVVALPDTSAFIHSPIQAXXXXXXXXXXXXXXXXXXXVSFPKYNNYVRSKNKFDKYTRV 1981
            ++ V LPDTSAF+ SP                      ++FPKYNNY+   N+FD Y+++
Sbjct: 2287 DQKVVLPDTSAFLSSP----------------AHFGPSITFPKYNNYMADPNRFDPYSKI 2330

Query: 1982 LLPLDLLGISN--NNLQDITDTNYETRAVFGYVQYSRNSSQLMPLRMDDSVSLRWGVNIT 2039
             +PLD+LGI        ++  +    +AV  YVQY +    L+P R DDSVS+RWGV + 
Sbjct: 2331 RVPLDILGIKTLMQGELNVKKSLVNRKAVLSYVQY-KQLGALLPQRFDDSVSVRWGVEVA 2389

Query: 2040 IGSPILQIAVFVPES 2054
            +GSP++ ++V VP +
Sbjct: 2390 VGSPVITVSVLVPSN 2404



 Score =  351 bits (864), Expect = 1e-94
 Identities = 272/864 (31%), Positives = 417/864 (48%), Gaps = 74/864 (8%)

Query: 15   DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
            +  + SP FE   Y A V E    G  V +++A D + G    V Y++  +        D
Sbjct: 253  ELKNQSPYFEQSLYVAVVEEEKEPGVYVTSVRARDPEGGT---VRYSMSSLL-------D 302

Query: 75   AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134
            A           Q +  +D  +G + TRA LDRE V  +   V A D + P     + T 
Sbjct: 303  ARS---------QALLVLDPVTGRVTTRARLDRESVDVHYFRVLAVDDSFPPR---TGTT 350

Query: 135  TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG- 193
            T+ VN++D ND+ P F       S+ E + V     +  +KATD D G N+ + Y+I+  
Sbjct: 351  TLQVNVLDTNDHAPSFEWPEEEASIREGVPV--GSTVVTVKATDQDAGRNAEVEYSILST 408

Query: 194  ------GNTQ--MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT---Q 242
                   NT+  + F ID  +G V+    LD E+   Y +++   D  +P  +  T    
Sbjct: 409  TSSSGTANTEDALIFRIDPRTGVVTTRTPLDREKTEVYTVILSVSDQATPPSARKTANAT 468

Query: 243  LLINIRDVNDNAPRFYTSLFQESVSENVPIGYS--IVRVQAYDADEGVNAELTYTMTDKD 300
            L++ + D NDN P+F    +   + E++    +  I R++A DAD G NA + Y +    
Sbjct: 469  LVVRVLDDNDNYPQFTERTYSAWIPEDLDYTANPVIARIRATDADSGNNAAVRYAIIG-- 526

Query: 301  YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
              GN     +ID   G V     LD E+   Y++++ A DGG P RS T           
Sbjct: 527  --GNTQNTFSIDSMVGDVALVKPLDYESTRSYKIVIRAQDGGSPARSNTTQLLVHVGDVN 584

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI-----TGGNTRGRFS 413
                 F    ++  ++E+ P G  ++ + A DADE  + ++ Y I     TG +T   F 
Sbjct: 585  DNAPRFYTSHFQESVSENVPVGYSILRIQAYDADEGANAQIKYTIGARDFTGASTE-NFP 643

Query: 414  ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFEN 471
            IT     G +   + LD +Q  RY  TV A DSG   +S +A V + +TD N+  P F+ 
Sbjct: 644  ITVNTETGWLYTTKQLDREQCSRYQFTVIAADSGEISKSASATVILTVTDVNDNDPYFDP 703

Query: 472  APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
              Y + V ED P GT V  V+ATD D   +A+I Y +++  +    A   Q        G
Sbjct: 704  KNYESVVSEDDPPGTPVTSVTATDPDE--DARIHYEITAGNTRGRFAIASQN-----GRG 756

Query: 532  AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
             IT  + LD +    ++LTVTA D G    +DT  V +++ D N+  PVF+   Y+ ++ 
Sbjct: 757  LITIAQPLDYKQEKRFVLTVTASDSG--GRTDTALVYVNISDANNFSPVFENAPYSVSVF 814

Query: 592  EDALVGTSVSQVGATDADVGLNGRIHYELDPK--DREEGSFVIDPASGVIRTNKALDRES 649
            EDA +GT+V  V ATD+DVG N ++ Y LD    D+    F+I+P +G I T K LDRE 
Sbjct: 815  EDAPIGTTVLVVSATDSDVGKNAQVTYSLDTDNGDQTASEFIINPQTGAITTTKPLDREI 874

Query: 650  VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
            V  + L   A DGG PP S T  V I + D+ND+ PVFE+      I E+  +GT++  +
Sbjct: 875  VPAYLLTVTARDGGIPPLSDTTDVEISVTDVNDNAPVFEAPQYQGSIPEDVLVGTSVLRV 934

Query: 710  RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY--ELVI 767
             A D D   N  V Y+++  D   +F++++  G     + T   LD ES  K     + +
Sbjct: 935  SATDADTDLNGRVRYALE-DDGDGAFAVDSTTGI----IRTAKPLDRESVAKYILKAVAM 989

Query: 768  RAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDK 826
               SP L   V V I + DVND+ P  ++ +II    ++  P+G   G + A+D D    
Sbjct: 990  DRGSPSLSTVVPVTIKIEDVNDSPPAFENDKIILYIAENS-PIGSTVGEIYAHDPDEGPN 1048

Query: 827  --LQYRILSGNNANLILLNETTGS 848
              +QY ++ G ++N   LN   G+
Sbjct: 1049 AVVQYSVIGGEDSNSFALNIRPGA 1072



 Score =  336 bits (825), Expect = 7e-90
 Identities = 245/764 (32%), Positives = 376/764 (49%), Gaps = 41/764 (5%)

Query: 148  PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
            P F +  Y   V+E+        +  ++A D + G       +++   +Q    +D ++G
Sbjct: 259  PYFEQSLYVAVVEEEKE--PGVYVTSVRARDPEGGTVRYSMSSLLDARSQALLVLDPVTG 316

Query: 208  DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
             V+    LD E V  +   + A D   P R+ TT L +N+ D ND+AP F     + S+ 
Sbjct: 317  RVTTRARLDRESVDVHYFRVLAVDDSFPPRTGTTTLQVNVLDTNDHAPSFEWPEEEASIR 376

Query: 268  ENVPIGYSIVRVQAYDADEGVNAELTYTM---TDKDYTGNVD--LPITIDPRSGWVYTSG 322
            E VP+G ++V V+A D D G NAE+ Y++   T    T N +  L   IDPR+G V T  
Sbjct: 377  EGVPVGSTVVTVKATDQDAGRNAEVEYSILSTTSSSGTANTEDALIFRIDPRTGVVTTRT 436

Query: 323  QLDRETQAKYQLLVTATDGGDPP---RSATATXXXXXXXXXXXXXXFMPGQYEVELAED- 378
             LDRE    Y ++++ +D   PP   ++A AT              F    Y   + ED 
Sbjct: 437  PLDREKTEVYTVILSVSDQATPPSARKTANATLVVRVLDDNDNYPQFTERTYSAWIPEDL 496

Query: 379  EPPGTPVVT-LTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435
            +    PV+  + ATDAD  N   + Y I GGNT+  FSI S  G   + + +PLD++  R
Sbjct: 497  DYTANPVIARIRATDADSGNNAAVRYAIIGGNTQNTFSIDSMVGD--VALVKPLDYESTR 554

Query: 436  RYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
             Y + + A D G   RS+T  + +++ D N+ AP F  + +  SV E+ P+G ++L + A
Sbjct: 555  SYKIVIRAQDGGSPARSNTTQLLVHVGDVNDNAPRFYTSHFQESVSENVPVGYSILRIQA 614

Query: 494  TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553
             D+D G NAQI Y++ +     A +  +    +N +TG + T K LDRE  S Y  TV A
Sbjct: 615  YDADEGANAQIKYTIGARDFTGA-STENFPITVNTETGWLYTTKQLDREQCSRYQFTVIA 673

Query: 554  RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613
             D G  S S +  V ++V DVNDN+P F  + Y + + ED   GT V+ V ATD D   +
Sbjct: 674  ADSGEISKSASATVILTVTDVNDNDPYFDPKNYESVVSEDDPPGTPVTSVTATDPDE--D 731

Query: 614  GRIHYELDPKDREEGSFVI--DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671
             RIHYE+       G F I      G+I   + LD +      L   A D G   ++ T 
Sbjct: 732  ARIHYEI-TAGNTRGRFAIASQNGRGLITIAQPLDYKQEKRFVLTVTASDSG--GRTDTA 788

Query: 672  IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI---KG 728
            +V++ I D N+  PVFE+   +  + E++PIGTT+  + A D D G NA V YS+    G
Sbjct: 789  LVYVNISDANNFSPVFENAPYSVSVFEDAPIGTTVLVVSATDSDVGKNAQVTYSLDTDNG 848

Query: 729  GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVT 785
               ++ F +  + G+    + T   LD E     Y L + A     PPL +   VEI VT
Sbjct: 849  DQTASEFIINPQTGA----ITTTKPLDREIV-PAYLLTVTARDGGIPPLSDTTDVEISVT 903

Query: 786  DVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDA--DVTDKLQYRILSGNNANLILLN 843
            DVNDNAPV +  Q   +  +D        RV A DA  D+  +++Y  L  +      ++
Sbjct: 904  DVNDNAPVFEAPQYQGSIPEDVLVGTSVLRVSATDADTDLNGRVRY-ALEDDGDGAFAVD 962

Query: 844  ETTGSM-TLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886
             TTG + T  P    +V K     V++  G   +  ++ +++++
Sbjct: 963  STTGIIRTAKPLDRESVAKYILKAVAMDRGSPSLSTVVPVTIKI 1006



 Score =  235 bits (574), Expect = 2e-59
 Identities = 179/654 (27%), Positives = 303/654 (46%), Gaps = 47/654 (7%)

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
           R++ + +P F  SL+   V E    G  +  V+A D + G    + Y+M+          
Sbjct: 252 RELKNQSPYFEQSLYVAVVEEEKEPGVYVTSVRARDPEGGT---VRYSMSSL-LDARSQA 307

Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
            + +DP +G V T  +LDRE+   +   V A D   PPR+ T T              F 
Sbjct: 308 LLVLDPVTGRVTTRARLDRESVDVHYFRVLAVDDSFPPRTGTTTLQVNVLDTNDHAPSFE 367

Query: 368 PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITG-------GNTRGRFSITSQN 418
             + E  + E  P G+ VVT+ ATD D   +  + Y I          NT          
Sbjct: 368 WPEEEASIREGVPVGSTVVTVKATDQDAGRNAEVEYSILSTTSSSGTANTEDALIFRIDP 427

Query: 419 GRGLITVAQPLDFKQERRYVLTVSATD-----SGGRSDTAMVQINITDANNYAPVFENAP 473
             G++T   PLD ++   Y + +S +D     S  ++  A + + + D N+  P F    
Sbjct: 428 RTGVVTTRTPLDREKTEVYTVILSVSDQATPPSARKTANATLVVRVLDDNDNYPQFTERT 487

Query: 474 YTASVFEDAPIGTTVLV--VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
           Y+A + ED       ++  + ATD+D G NA + Y++          +    F I+   G
Sbjct: 488 YSAWIPEDLDYTANPVIARIRATDADSGNNAAVRYAIIG-------GNTQNTFSIDSMVG 540

Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
            +   K LD E+   Y + + A+DGG P+ S+TT + + V DVNDN P F    +  ++ 
Sbjct: 541 DVALVKPLDYESTRSYKIVIRAQDGGSPARSNTTQLLVHVGDVNDNAPRFYTSHFQESVS 600

Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKD-----REEGSFVIDPASGVIRTNKALD 646
           E+  VG S+ ++ A DAD G N +I Y +  +D      E     ++  +G + T K LD
Sbjct: 601 ENVPVGYSILRIQAYDADEGANAQIKYTIGARDFTGASTENFPITVNTETGWLYTTKQLD 660

Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706
           RE  + +    +A D G   +S++  V + + D+ND+ P F+       +SE+ P GT +
Sbjct: 661 REQCSRYQFTVIAADSGEISKSASATVILTVTDVNDNDPYFDPKNYESVVSEDDPPGTPV 720

Query: 707 GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYEL 765
             + A DPDE  +A +HY I  G+    F++ ++ G     L+T+   LDY+   K++ L
Sbjct: 721 TSVTATDPDE--DARIHYEITAGNTRGRFAIASQNGRG---LITIAQPLDYKQ-EKRFVL 774

Query: 766 VIRAASPPLWNDVR-VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR-VPAYDADV 823
            + A+      D   V + ++D N+ +PV ++     + ++D  P+G     V A D+DV
Sbjct: 775 TVTASDSGGRTDTALVYVNISDANNFSPVFENAPYSVSVFEDA-PIGTTVLVVSATDSDV 833

Query: 824 TDKLQ--YRILSGN---NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
               Q  Y + + N    A+  ++N  TG++T +  L+  +     + V+  DG
Sbjct: 834 GKNAQVTYSLDTDNGDQTASEFIINPQTGAITTTKPLDREIVPAYLLTVTARDG 887



 Score =  193 bits (470), Expect = 7e-47
 Identities = 93/163 (57%), Positives = 121/163 (74%), Gaps = 5/163 (3%)

Query: 2168 YRSLSGIRLKKPIRLQIWLDINRETFGSRTNPQCVHWSTLRGSGEWSRVGCHTEIDYDWS 2227
            Y SL+GI L+ P+++ +WL   ++   +RTNPQCVHWST RG GEWSR+GC TE + D  
Sbjct: 2407 YMSLTGIPLQSPVQISLWLS-EKDDIKTRTNPQCVHWSTARGVGEWSRMGCTTESEDDSL 2465

Query: 2228 PYSEEPLLINCTCNHLSTFAVLVDEVDVEFIPEPSLLESVTSYTAFSISLPLLLTSWAAL 2287
             +     ++NC+C  LSTFA+L D +D E++PEPSLLE VTSY+AF ++LPLLL++   L
Sbjct: 2466 SFGT---IVNCSCFQLSTFAILTDVLDPEYVPEPSLLEDVTSYSAFMLALPLLLSALLIL 2522

Query: 2288 CLIRGGAATVSNSIHKHLIFSVFMAELLYLIALKARTSLVQNE 2330
             LIRGG  T SNSIHK+L+  VF AE+LYLIALKAR+ LV NE
Sbjct: 2523 ALIRGG-GTNSNSIHKNLVMCVFFAEVLYLIALKARSPLVSNE 2564



 Score =  111 bits (266), Expect = 4e-22
 Identities = 91/328 (27%), Positives = 145/328 (44%), Gaps = 22/328 (6%)

Query: 563 DTTDVEISVV-DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621
           D TD+   V  ++ +  P F+Q LY A + E+   G  V+ V A D +    G + Y + 
Sbjct: 242 DDTDLGRRVRRELKNQSPYFEQSLYVAVVEEEKEPGVYVTSVRARDPE---GGTVRYSMS 298

Query: 622 P--KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679
                R +   V+DP +G + T   LDRESV  H  + +A+D   PP++ T  + + + D
Sbjct: 299 SLLDARSQALLVLDPVTGRVTTRARLDRESVDVHYFRVLAVDDSFPPRTGTTTLQVNVLD 358

Query: 680 INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-----KGGDDSNS 734
            ND  P FE       I E  P+G+T+  ++A D D G NA V YSI       G  +  
Sbjct: 359 TNDHAPSFEWPEEEASIREGVPVGSTVVTVKATDQDAGRNAEVEYSILSTTSSSGTANTE 418

Query: 735 FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN---DVRVEILVTDVN 788
            +L  R       + T   LD E   + Y +++     A+PP      +  + + V D N
Sbjct: 419 DALIFRIDPRTGVVTTRTPLDREK-TEVYTVILSVSDQATPPSARKTANATLVVRVLDDN 477

Query: 789 DNAPVMKDFQIIFNNYKDC-FPVGP-FGRVPAYDADVTDK--LQYRILSGNNANLILLNE 844
           DN P   +        +D  +   P   R+ A DAD  +   ++Y I+ GN  N   ++ 
Sbjct: 478 DNYPQFTERTYSAWIPEDLDYTANPVIARIRATDADSGNNAAVRYAIIGGNTQNTFSIDS 537

Query: 845 TTGSMTLSPQLNTNVPKLATMEVSVTDG 872
             G + L   L+    +   + +   DG
Sbjct: 538 MVGDVALVKPLDYESTRSYKIVIRAQDG 565



 Score = 91.9 bits (218), Expect = 2e-16
 Identities = 67/223 (30%), Positives = 96/223 (43%), Gaps = 12/223 (5%)

Query: 2330 EPVVWWVVIPXXXXXXXXXXXXXXXXXXXFTVRDHVTGFGNLRMLLAVSIVCLPLLCVAW 2389
            E V+W ++ P                   FT+++H+ GFGNLR LL +S+  LPLL   W
Sbjct: 2645 ETVIWSLIGPICLAIFVNFCILVMSIRAAFTLKEHIMGFGNLRTLLWLSVASLPLLGSTW 2704

Query: 2390 ASALLLGSEAGGRRXXXXXXXXXXXXXXXIAASLGYIAFNVRVRDNLKRTVLRCMGKKVP 2449
               +L  SE                    +   +GY   N RVR NL  ++LRC+GKK P
Sbjct: 2705 TLTVLNASENSPTLSYLLSIAVVVHASFSL---IGYCFINGRVRRNLYLSLLRCIGKKTP 2761

Query: 2450 LADTSVIISSSAHNLSQVNRSSLAYHSSTEPGRQ--MRNIGIXXXXXXXXXXXXXXXXXX 2507
            L + S+   SS+ N++  +RS+LAY SST  G +   R + +                  
Sbjct: 2762 LLEGSMGNGSSSQNVNGHSRSALAY-SSTYSGAESVCRRVHVGVSTSSTTSRSTNKTGSS 2820

Query: 2508 -XXXDGQLRHXXXXXXXXXXXASDMPAYL--RGFDSSLHTRKD 2547
                D  LRH            SD   YL  R   S+LH+R++
Sbjct: 2821 PYRSDTHLRHTSTSTSNYN---SDRDPYLSSRSHRSTLHSRQE 2860



 Score = 36.7 bits (81), Expect = 9.2
 Identities = 25/55 (45%), Positives = 30/55 (54%), Gaps = 7/55 (12%)

Query: 2572 SPRWPSHVREDQ-SRPEM----GRWSQETGSDNEGANMGIATPSPNPLPNPDLTS 2621
            +PRW S + E   S   M     +WS  T SDNE A+    T SPNPLP PD+ S
Sbjct: 2950 APRWSSQLPEAYLSSNAMDVRGSQWSGGTISDNEMASN--KTSSPNPLPYPDMNS 3002


>UniRef50_Q4S7X0 Cluster: Chromosome 9 SCAF14710, whole genome shotgun
            sequence; n=6; Clupeocephala|Rep: Chromosome 9 SCAF14710,
            whole genome shotgun sequence - Tetraodon nigroviridis
            (Green puffer)
          Length = 4006

 Score = 1381 bits (3421), Expect = 0.0
 Identities = 775/1980 (39%), Positives = 1107/1980 (55%), Gaps = 191/1980 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D NDHSP+FE  +Y  ++RE    G  +L L+ATD D   NA + Y       D +
Sbjct: 1024 ITVSDRNDHSPIFEQTEYRETIRENVEEGYPILQLRATDSDSPTNANIRYRF---IGDMV 1080

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                            +  F ID RSG + TR  +DRE    YT+ V+A+DQ      R 
Sbjct: 1081 -------------AVARAAFEIDPRSGLITTRGVVDRELNEHYTLQVEASDQGKEPGPR- 1126

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S+T  + + ++D+NDN PQFSEK Y V+V E+  V  +  I ++ ATD D  +N+A+ Y 
Sbjct: 1127 SATVKVFITVLDENDNVPQFSEKRYVVAVKEN--VRPHSEILRVSATDRDKDSNAAVHYN 1184

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIRD 249
            II GN++ QFSIDS++G++ +V  LDYE  R Y L +RAQD G P  SN T ++ + + D
Sbjct: 1185 IISGNSRGQFSIDSVTGEIQVVAPLDYEAEREYTLRVRAQDNGRPPLSNNTGIVSVQVTD 1244

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            VNDN P F ++ FQ SV E+ P+G SI+ +QA D D G NA L Y +T      + D P 
Sbjct: 1245 VNDNPPIFVSTPFQASVLESSPVGSSILHIQAIDTDSGDNARLEYKLTGT----SSDTPF 1300

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             I+  +GWV     LDRE+   Y   V A D G PP SATA+              F+  
Sbjct: 1301 IINSATGWVTVRSTLDRESVEHYFFGVEARDYGTPPLSATASVTITVMDVNDNHPEFLQK 1360

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
            +Y   L ED   GT VVT+TA D D ++ + Y+ITGGNTR RF+I++  G GL+++A PL
Sbjct: 1361 EYYARLNEDAAVGTSVVTVTAVDRDVNSAVTYQITGGNTRNRFAISTAGGAGLLSLALPL 1420

Query: 430  DFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
            D+KQERRYVLTV+A+D     DT  V INITDAN + PVF++A Y+ SV ED+P G+ V+
Sbjct: 1421 DYKQERRYVLTVTASDR-TLHDTCQVHINITDANTHRPVFQSAHYSVSVNEDSPPGSLVV 1479

Query: 490  VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
            ++SATD DVG NA+ITY L   I          QF I+  TGAIT    LD E    Y L
Sbjct: 1480 MISATDDDVGENARITYLLEDNI---------PQFRIDSATGAITLQAELDYEDQMTYTL 1530

Query: 550  TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
             +TA+D G+P  SDTT VE++V DVNDN P F    Y  ++ EDA   TSV Q+ ATD D
Sbjct: 1531 AITAKDNGIPQKSDTTYVEVNVNDVNDNAPQFLSPRYQGSVSEDAPPFTSVLQISATDRD 1590

Query: 610  VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669
               NGR+ Y     +  +G F I+P SG++RT +A                    PPQ +
Sbjct: 1591 AHANGRVQYTFQNGEDGDGDFTIEPTSGILRTIEA-------------------CPPQRT 1631

Query: 670  TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729
             V + + + D+ND  PVF +D     + ENS +G+ + +I A DPDEG NA + Y I  G
Sbjct: 1632 PVHIQVTVLDVNDKAPVFPADDFEVLVKENSAVGSVVAQITATDPDEGANAQIMYQIVEG 1691

Query: 730  DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVND 789
            +    F ++   G    EL +++DLDYE+ R +Y +V++A S PL +   V I + D ND
Sbjct: 1692 NIPEIFQMDIFSG----ELTSLIDLDYET-RNEYVIVVQATSAPLVSRATVRIKLVDQND 1746

Query: 790  NAPVMKDFQIIFNNY----KDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNET 845
            N P ++DFQIIFNN+     + FP G  GR+PA+D DV+D+L Y I  GN  +L+LLN T
Sbjct: 1747 NRPTLQDFQIIFNNFVSNRSNSFPSGVIGRIPAHDPDVSDRLYYTIDRGNELHLLLLNHT 1806

Query: 846  TGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTA 905
            +G + LS +L+ N P +A M ++VTDG++ I A   L V +ITE+ML +S+TVRL +M+ 
Sbjct: 1807 SGEIRLSRKLDNNRPLVAPMLITVTDGIHSISAQCVLRVLIITEDMLGSSVTVRLQNMSQ 1866

Query: 906  EQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVT-GNILNVSFSARRPDAEVGVAG 964
            E FLSPLLG F++G++A++  P E+++IF++Q D D   G ILNVSFSA  P    G   
Sbjct: 1867 EHFLSPLLGNFLEGVSAVLSVPVEDVFIFNIQPDLDAAPGRILNVSFSAALP----GGLF 1922

Query: 965  DPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASG 1024
             PS       L E++YL+R  L  L  ++VLPFDDN+C+ EPC N+ +C++VL+F +++ 
Sbjct: 1923 FPS-----EALEEQLYLNRPRLTSLTQMEVLPFDDNVCLREPCKNYMKCVSVLRFNSSAP 1977

Query: 1025 FVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSIC---RSGSQCVA 1081
            F++S S+LFRPI+P+    C+CP GFTG  CET +         +G +C     G  C+ 
Sbjct: 1978 FISSPSILFRPIHPIAGLRCRCPVGFTGDYCETEINLCYSNPCLNGGVCAPREGGFTCIC 2037

Query: 1082 R------------REGGI---LCQG-------------CSI-DAAYTTAVCELRARSFPV 1112
            R            R+GG    +C+              C   + AY    C + ARSFP 
Sbjct: 2038 RENYTGDRCEFDHRQGGCVPGVCRNGGTCLELSRGGFRCECPEGAYEPPYCAVTARSFPP 2097

Query: 1113 SSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRGGGPGL 1172
             SF  F GL++R  + + L FAT   SGLL YNGR+NE+HDF+ALE+   +        +
Sbjct: 2098 KSFAMFRGLRQRFHLTISLTFATLENSGLLFYNGRFNEKHDFIALEIQEGQ--------V 2149

Query: 1173 RFSFSLGGGKSEIT--VEGNVGDGSWHTVEIEYFNRTITMI----------------LDD 1214
               +S G   +++T  + G V DG+WH+V I Y+N+    I                +DD
Sbjct: 2150 VLKYSTGESSTQVTPFLPGGVSDGNWHSVHIHYYNKPKRSIGGEAQGPSDEKIAVVRVDD 2209

Query: 1215 CDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSF 1274
            CD  LSL  +   G  Y+CA           +    +  + LDLTGPL +GG+PN   +F
Sbjct: 2210 CDAALSLRFSTQLG-NYSCA----------AQGKQSSSKKSLDLTGPLFLGGVPNGADNF 2258

Query: 1275 QVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDT 1334
               +++F+GC+ DF+ID+K +DL  ++A+NGT AGC  K   C+S PC NG  C   W+T
Sbjct: 2259 PFSSREFIGCLKDFHIDNKQLDLAGFIANNGTTAGCSAKTPFCNSNPCQNGGTCRVGWET 2318

Query: 1335 YICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLR-PIQLPWLNALSIRTRQRDAFVM 1393
            ++CDC  G+ GKDC+     P RF G+ +  ++      I  PW   L  RTR R+  ++
Sbjct: 2319 FLCDCPLGYGGKDCSHVMPHPHRFLGNSVQWWDLKNEVTISTPWYLGLVFRTRSREGTLL 2378

Query: 1394 SIQL--KSGLLHYSYNGETMY-------------LPMATLSDGAWH--RIEIKWLGTD-- 1434
              Q    + LL    N + ++             L    ++DG WH  ++E++ + +D  
Sbjct: 2379 QAQAGQYTSLLFQVVNSQLVFSVTRGAARPVRLRLDQVLVADGRWHDLQLELRDVRSDRE 2438

Query: 1435 ----ISVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGLLASDVGFFEGCIQDVR 1490
                 ++ +D+G+    + ++ N+I G  +  + +GG+   +G + + +    GCIQ VR
Sbjct: 2439 TRYVATLRLDFGIYQGTV-IVGNEIHGLKVKHLHVGGV-FGSGKVQNGI---RGCIQGVR 2493

Query: 1491 IGTAQSL--LNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC 1548
            +G       L  PT   NV  GC     C+ S CP +S+C   W+  TC C+ G  G  C
Sbjct: 2494 LGVRPDAPPLRPPTRTVNVEAGCNVGNYCVSSPCPTHSRCADQWERHTCVCDPGYYGKSC 2553

Query: 1549 VSACELGPC-GAARC-VPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGP 1606
              AC L PC   A+C     +  GY C C  G       C      +CP GWWG   CGP
Sbjct: 2554 TDACHLNPCENEAQCHRKPSSSHGYVCDC--GDNHFGQYCQHRSDHQCPRGWWGSPTCGP 2611

Query: 1607 CACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCR 1666
            C CD  +G+ P+CNK +G CHCKE HY P G+  CLPC CY  GS + SC+A TGQC CR
Sbjct: 2612 CDCDTDKGFDPNCNKTSGHCHCKEFHYHPRGSDTCLPCDCYPVGSFSRSCDAETGQCQCR 2671

Query: 1667 PGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSG 1726
            PGVIGR C+AC N +AEVT NSGCEV+YDGCP++   G+WWPRTKF         P   G
Sbjct: 2672 PGVIGRQCNACDNPFAEVT-NSGCEVIYDGCPKTITQGIWWPRTKF--------TPACGG 2722

Query: 1727 RATRTCDETKDVPWQDPDMFNCTTATFYQLRKQLHKIETGELTMNTFVGVRVAADLSTAC 1786
             A R CD  +   W +P+++NCT+  F +L   L  +E  E  ++T +  ++A  L    
Sbjct: 2723 AAIRHCDVERG--WLEPELYNCTSPPFVELNAALDSLERNETELSTIMEKKLAHQLRDVT 2780

Query: 1787 ANTPRLYGADVVVAEGILLELMDYELRQAGLNLTHSQDKDYVRNLLKSTNTILNVEYERE 1846
              T RLYG D+ +AE +L  L+++E +Q+G  LT +QD  +  NL+++ + +L       
Sbjct: 2781 EATARLYGNDLHIAERLLSRLLNFETQQSGFGLTATQDAYFNENLIRACSALLGPGTSGL 2840

Query: 1847 WKRI----RELTGHGAELLVQKFDEYIAVLAESQHDTYTSPFEIVTKDVVISVDTVTSES 1902
            W+ +      + G G   L     +Y   LA++   TY +P  +V  ++V+++D V +++
Sbjct: 2841 WRALIQSQNHIQGGGPAELTGLLRQYSQNLAKNMKLTYLNPVALVAPNLVMNLDRVETQT 2900



 Score =  345 bits (849), Expect = 8e-93
 Identities = 238/711 (33%), Positives = 360/711 (50%), Gaps = 42/711 (5%)

Query: 145  DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA---IIGGNTQMQFS 201
            + +P F +  Y V V E+     + ++  + A+D D G    + Y+   ++   +   F 
Sbjct: 923  NRHPFFPQYNYQVQVAENQPPGTSVIL--MSASDPDPGDAGRVSYSMAPLMNSRSSDYFH 980

Query: 202  IDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261
            I   +G ++  +TLD E +  +   + A D GS   S TT + I + D ND++P F  + 
Sbjct: 981  IHPETGLITTTQTLDREHMDLHYFRVTATDYGSSRLSGTTMVAITVSDRNDHSPIFEQTE 1040

Query: 262  FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321
            ++E++ ENV  GY I++++A D+D   NA + Y     D          IDPRSG + T 
Sbjct: 1041 YRETIRENVEEGYPILQLRATDSDSPTNANIRYRFIG-DMVAVARAAFEIDPRSGLITTR 1099

Query: 322  GQLDRETQAKYQLLVTATDGG-DP-PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE 379
            G +DRE    Y L V A+D G +P PRSAT                F   +Y V + E+ 
Sbjct: 1100 GVVDRELNEHYTLQVEASDQGKEPGPRSATVKVFITVLDENDNVPQFSEKRYVVAVKENV 1159

Query: 380  PPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437
             P + ++ ++ATD D+D+   +HY I  GN+RG+FSI S  G   I V  PLD++ ER Y
Sbjct: 1160 RPHSEILRVSATDRDKDSNAAVHYNIISGNSRGQFSIDSVTGE--IQVVAPLDYEAEREY 1217

Query: 438  VLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494
             L V A D+G     ++T +V + +TD N+  P+F + P+ ASV E +P+G+++L + A 
Sbjct: 1218 TLRVRAQDNGRPPLSNNTGIVSVQVTDVNDNPPIFVSTPFQASVLESSPVGSSILHIQAI 1277

Query: 495  DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554
            D+D G NA++ Y L+   S       D  F+IN  TG +T    LDRE++  Y   V AR
Sbjct: 1278 DTDSGDNARLEYKLTGTSS-------DTPFIINSATGWVTVRSTLDRESVEHYFFGVEAR 1330

Query: 555  DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614
            D G P LS T  V I+V+DVNDN P F Q+ Y A + EDA VGTSV  V A D DV  N 
Sbjct: 1331 DYGTPPLSATASVTITVMDVNDNHPEFLQKEYYARLNEDAAVGTSVVTVTAVDRDV--NS 1388

Query: 615  RIHYELDPKDREEGSFVIDPA--SGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672
             + Y++   +     F I  A  +G++     LD +    + L   A D        T  
Sbjct: 1389 AVTYQITGGNTRN-RFAISTAGGAGLLSLALPLDYKQERRYVLTVTASDRTL---HDTCQ 1444

Query: 673  VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732
            VHI I D N   PVF+S   +  ++E+SP G+ +  I A D D G NA + Y ++  D+ 
Sbjct: 1445 VHINITDANTHRPVFQSAHYSVSVNEDSPPGSLVVMISATDDDVGENARITYLLE--DNI 1502

Query: 733  NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVND 789
              F +++  G+    +    +LDYE  +  Y L I A     P   +   VE+ V DVND
Sbjct: 1503 PQFRIDSATGA----ITLQAELDYED-QMTYTLAITAKDNGIPQKSDTTYVEVNVNDVND 1557

Query: 790  NAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNAN 838
            NAP     +   +  +D  P     ++ A D D     ++QY   +G + +
Sbjct: 1558 NAPQFLSPRYQGSVSEDAPPFTSVLQISATDRDAHANGRVQYTFQNGEDGD 1608



 Score =  330 bits (812), Expect = 2e-88
 Identities = 264/852 (30%), Positives = 400/852 (46%), Gaps = 85/852 (9%)

Query: 17   NDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAX 76
            N H P F    Y+  V E    GT+V+ + A+D D G    V Y++    A  +N   + 
Sbjct: 923  NRH-PFFPQYNYQVQVAENQPPGTSVILMSASDPDPGDAGRVSYSM----APLMNSRSS- 976

Query: 77   XXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATI 136
                       D F I   +G + T  +LDRE +  +   V ATD  S    RLS T  +
Sbjct: 977  -----------DYFHIHPETGLITTTQTLDREHMDLHYFRVTATDYGS---SRLSGTTMV 1022

Query: 137  HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNT 196
             + + D ND+ P F +  Y  ++ E++   +   I +++ATD+D   N+ IRY  IG   
Sbjct: 1023 AITVSDRNDHSPIFEQTEYRETIRENVE--EGYPILQLRATDSDSPTNANIRYRFIGDMV 1080

Query: 197  QMQ---FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS--RSNTTQLLINIRDVN 251
             +    F ID  SG ++    +D E    Y L + A D G     RS T ++ I + D N
Sbjct: 1081 AVARAAFEIDPRSGLITTRGVVDRELNEHYTLQVEASDQGKEPGPRSATVKVFITVLDEN 1140

Query: 252  DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311
            DN P+F    +  +V ENV     I+RV A D D+  NA + Y +     +GN     +I
Sbjct: 1141 DNVPQFSEKRYVVAVKENVRPHSEILRVSATDRDKDSNAAVHYNII----SGNSRGQFSI 1196

Query: 312  DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA-TATXXXXXXXXXXXXXXFMPGQ 370
            D  +G +     LD E + +Y L V A D G PP S  T                F+   
Sbjct: 1197 DSVTGEIQVVAPLDYEAEREYTLRVRAQDNGRPPLSNNTGIVSVQVTDVNDNPPIFVSTP 1256

Query: 371  YEVELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
            ++  + E  P G+ ++ + A D D  DN RL Y++TG ++   F I S  G   +TV   
Sbjct: 1257 FQASVLESSPVGSSILHIQAIDTDSGDNARLEYKLTGTSSDTPFIINSATG--WVTVRST 1314

Query: 429  LDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
            LD +    Y   V A D G    S TA V I + D N+  P F    Y A + EDA +GT
Sbjct: 1315 LDRESVEHYFFGVEARDYGTPPLSATASVTITVMDVNDNHPEFLQKEYYARLNEDAAVGT 1374

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA--ITTNKLLDRETM 544
            +V+ V+A D DV  N+ +TY ++         +   +F I+   GA  ++    LD +  
Sbjct: 1375 SVVTVTAVDRDV--NSAVTYQITG-------GNTRNRFAISTAGGAGLLSLALPLDYKQE 1425

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
              Y+LTVTA D    +L DT  V I++ D N + PVF+   Y+ ++ ED+  G+ V  + 
Sbjct: 1426 RRYVLTVTASDR---TLHDTCQVHINITDANTHRPVFQSAHYSVSVNEDSPPGSLVVMIS 1482

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            ATD DVG N RI Y L+    +   F ID A+G I     LD E   T+ L   A D G 
Sbjct: 1483 ATDDDVGENARITYLLEDNIPQ---FRIDSATGAITLQAELDYEDQMTYTLAITAKDNGI 1539

Query: 665  PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
            P +S T  V + + D+ND+ P F S      +SE++P  T++ +I A D D   N  V Y
Sbjct: 1540 PQKSDTTYVEVNVNDVNDNAPQFLSPRYQGSVSEDAPPFTSVLQISATDRDAHANGRVQY 1599

Query: 725  SIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEIL 783
            + + G+D +  F++E   G     ++  ++                A PP    V +++ 
Sbjct: 1600 TFQNGEDGDGDFTIEPTSG-----ILRTIE----------------ACPPQRTPVHIQVT 1638

Query: 784  VTDVNDNAPVM--KDFQIIFNNYKDCFPVGP-FGRVPAYDAD--VTDKLQYRILSGNNAN 838
            V DVND APV    DF+++    K+   VG    ++ A D D     ++ Y+I+ GN   
Sbjct: 1639 VLDVNDKAPVFPADDFEVL---VKENSAVGSVVAQITATDPDEGANAQIMYQIVEGNIPE 1695

Query: 839  LILLNETTGSMT 850
            +  ++  +G +T
Sbjct: 1696 IFQMDIFSGELT 1707



 Score =  270 bits (662), Expect = 4e-70
 Identities = 203/666 (30%), Positives = 305/666 (45%), Gaps = 28/666 (4%)

Query: 218  EQVRSYRLVIRAQDGGSPSRSNTTQLLI--NIRDVNDNAPRFYTSLFQESVSENVPIGYS 275
            EQ    RL+I   D  S         ++    R   +  P F    +Q  V+EN P G S
Sbjct: 887  EQSSLERLIIAGDDKTSQGEGEEKNRMLWSRSRRAANRHPFFPQYNYQVQVAENQPPGTS 946

Query: 276  IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL 335
            ++ + A D D G    ++Y+M     + + D    I P +G + T+  LDRE    +   
Sbjct: 947  VILMSASDPDPGDAGRVSYSMAPLMNSRSSDY-FHIHPETGLITTTQTLDREHMDLHYFR 1005

Query: 336  VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395
            VTATD G    S T                F   +Y   + E+   G P++ L ATD+D 
Sbjct: 1006 VTATDYGSSRLSGTTMVAITVSDRNDHSPIFEQTEYRETIRENVEEGYPILQLRATDSDS 1065

Query: 396  DNR--LHYEITGGNT---RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG-- 448
                 + Y   G      R  F I  ++G  LIT    +D +    Y L V A+D G   
Sbjct: 1066 PTNANIRYRFIGDMVAVARAAFEIDPRSG--LITTRGVVDRELNEHYTLQVEASDQGKEP 1123

Query: 449  --RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506
              RS T  V I + D N+  P F    Y  +V E+    + +L VSATD D   NA + Y
Sbjct: 1124 GPRSATVKVFITVLDENDNVPQFSEKRYVVAVKENVRPHSEILRVSATDRDKDSNAAVHY 1183

Query: 507  SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566
            ++ S  S         QF I+  TG I     LD E    Y L V A+D G P LS+ T 
Sbjct: 1184 NIISGNSRG-------QFSIDSVTGEIQVVAPLDYEAEREYTLRVRAQDNGRPPLSNNTG 1236

Query: 567  -VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625
             V + V DVNDN P+F    + A+++E + VG+S+  + A D D G N R+ Y+L     
Sbjct: 1237 IVSVQVTDVNDNPPIFVSTPFQASVLESSPVGSSILHIQAIDTDSGDNARLEYKLTGTSS 1296

Query: 626  EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685
            +   F+I+ A+G +     LDRESV  +     A D GTPP S+T  V I + D+ND+ P
Sbjct: 1297 DT-PFIINSATGWVTVRSTLDRESVEHYFFGVEARDYGTPPLSATASVTITVMDVNDNHP 1355

Query: 686  VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745
             F        ++E++ +GT++  + A D D   N+ V Y I GG+  N F++ T  G+  
Sbjct: 1356 EFLQKEYYARLNEDAAVGTSVVTVTAVDRDV--NSAVTYQITGGNTRNRFAISTAGGAGL 1413

Query: 746  AELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYK 805
              L   + LDY+  R+ Y L + A+   L +  +V I +TD N + PV +      +  +
Sbjct: 1414 LSLA--LPLDYKQERR-YVLTVTASDRTLHDTCQVHINITDANTHRPVFQSAHYSVSVNE 1470

Query: 806  DCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATM 865
            D  P      + A D DV +  +   L  +N     ++  TG++TL  +L+       T+
Sbjct: 1471 DSPPGSLVVMISATDDDVGENARITYLLEDNIPQFRIDSATGAITLQAELDYEDQMTYTL 1530

Query: 866  EVSVTD 871
             ++  D
Sbjct: 1531 AITAKD 1536



 Score =  239 bits (585), Expect = 8e-61
 Identities = 169/527 (32%), Positives = 255/527 (48%), Gaps = 21/527 (3%)

Query: 371  YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITG-GNTRGRFSITSQNGRGLITVAQ 427
            Y+V++AE++PPGT V+ ++A+D D  +  R+ Y +    N+R           GLIT  Q
Sbjct: 933  YQVQVAENQPPGTSVILMSASDPDPGDAGRVSYSMAPLMNSRSSDYFHIHPETGLITTTQ 992

Query: 428  PLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
             LD +    +   V+ATD G    S T MV I ++D N+++P+FE   Y  ++ E+   G
Sbjct: 993  TLDREHMDLHYFRVTATDYGSSRLSGTTMVAITVSDRNDHSPIFEQTEYRETIRENVEEG 1052

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
              +L + ATDSD   NA I Y    ++   AVA     F I+P++G ITT  ++DRE   
Sbjct: 1053 YPILQLRATDSDSPTNANIRYRFIGDMV--AVAR--AAFEIDPRSGLITTRGVVDRELNE 1108

Query: 546  GYLLTVTARDGGVPS--LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
             Y L V A D G      S T  V I+V+D NDN P F ++ Y   + E+    + + +V
Sbjct: 1109 HYTLQVEASDQGKEPGPRSATVKVFITVLDENDNVPQFSEKRYVVAVKENVRPHSEILRV 1168

Query: 604  GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
             ATD D   N  +HY +       G F ID  +G I+    LD E+   + L+  A D G
Sbjct: 1169 SATDRDKDSNAAVHYNII-SGNSRGQFSIDSVTGEIQVVAPLDYEAEREYTLRVRAQDNG 1227

Query: 664  TPPQSS-TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
             PP S+ T IV +++ D+ND+PP+F S      + E+SP+G++I  I+A D D G NA +
Sbjct: 1228 RPPLSNNTGIVSVQVTDVNDNPPIFVSTPFQASVLESSPVGSSILHIQAIDTDSGDNARL 1287

Query: 723  HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVR 779
             Y + G      F + +  G     +     LD ES  + Y   + A    +PPL     
Sbjct: 1288 EYKLTGTSSDTPFIINSATGW----VTVRSTLDRESV-EHYFFGVEARDYGTPPLSATAS 1342

Query: 780  VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANL 839
            V I V DVNDN P     +      +D         V A D DV   + Y+I  GN  N 
Sbjct: 1343 VTITVMDVNDNHPEFLQKEYYARLNEDAAVGTSVVTVTAVDRDVNSAVTYQITGGNTRNR 1402

Query: 840  ILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886
              ++   G+  LS  L  +  +     ++VT     +    Q+ + +
Sbjct: 1403 FAISTAGGAGLLSLALPLDYKQERRYVLTVTASDRTLHDTCQVHINI 1449



 Score = 86.6 bits (205), Expect = 9e-15
 Identities = 67/230 (29%), Positives = 107/230 (46%), Gaps = 33/230 (14%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            +H Q+ VLD ND +PVF    +E  V+E ++ G+ V  + ATD D G NA++ Y I    
Sbjct: 1633 VHIQVTVLDVNDKAPVFPADDFEVLVKENSAVGSVVAQITATDPDEGANAQIMYQI---- 1688

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
                               + ++F++D  SG L +   LD E    Y ++V+AT      
Sbjct: 1689 ---------------VEGNIPEIFQMDIFSGELTSLIDLDYETRNEYVIVVQAT------ 1727

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP----VIAKIKATDADVG 182
            S  L S AT+ + ++D NDN P   +  + +  +  +S   N     VI +I A D DV 
Sbjct: 1728 SAPLVSRATVRIKLVDQNDNRPTLQD--FQIIFNNFVSNRSNSFPSGVIGRIPAHDPDV- 1784

Query: 183  ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232
             +  + Y I  GN      ++  SG++ L + LD  +     ++I   DG
Sbjct: 1785 -SDRLYYTIDRGNELHLLLLNHTSGEIRLSRKLDNNRPLVAPMLITVTDG 1833



 Score = 50.8 bits (116), Expect = 5e-04
 Identities = 23/54 (42%), Positives = 34/54 (62%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIE 63
            ++NV D ND++P F   +Y+ SV E A   T+VL + ATD+D   N  V+YT +
Sbjct: 1549 EVNVNDVNDNAPQFLSPRYQGSVSEDAPPFTSVLQISATDRDAHANGRVQYTFQ 1602



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 41/146 (28%), Positives = 68/146 (46%), Gaps = 12/146 (8%)

Query: 2176 LKKPIRLQIWLDINRETFGSRTNPQCVHWSTLRGSGEWSRVGCHTEIDYDWSPYSEEPLL 2235
            L +P+ L+  L    ET  +R+ P CV W+    S +    GC T    D          
Sbjct: 3049 LDQPVLLEFKL---LET-ANRSKPLCVQWNH---SSQHDLGGCWTV--RDCMVVYRNTSH 3099

Query: 2236 INCTCNHLSTFAVLVDEVDVEFIPEPSLLESVTSYTAFSIS-LPLLLTSWAALCLIRGGA 2294
            + C C  L TF VL+D    E +       ++ +Y+   +S L L+LT     CL   G 
Sbjct: 3100 VRCQCQRLGTFGVLMDSSQREQLEGDLETLALVTYSTLCLSMLALILTVLVLSCL--RGL 3157

Query: 2295 ATVSNSIHKHLIFSVFMAELLYLIAL 2320
             + + SIH +   ++F++EL++L+ +
Sbjct: 3158 KSNTRSIHSNTAAAMFLSELVFLLGI 3183


>UniRef50_Q9NYQ6 Cluster: Cadherin EGF LAG seven-pass G-type receptor
            1 precursor; n=45; Eukaryota|Rep: Cadherin EGF LAG
            seven-pass G-type receptor 1 precursor - Homo sapiens
            (Human)
          Length = 3014

 Score =  922 bits (2281), Expect = 0.0
 Identities = 494/1116 (44%), Positives = 688/1116 (61%), Gaps = 73/1116 (6%)

Query: 13   VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72
            V D NDHSPVFE  +Y   VRE    G  VLT++A+D+D   NA + Y +          
Sbjct: 343  VKDTNDHSPVFEQSEYRERVRENLEVGYEVLTIRASDRDSPINANLRYRV---------- 392

Query: 73   EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132
                           DVF+++  SG + TRA LDRE+ A Y +LV+A DQ       LS+
Sbjct: 393  ----------LGGAWDVFQLNESSGVVSTRAVLDREEAAEYQLLVEANDQGRNPGP-LSA 441

Query: 133  TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192
            TAT+++ + D+NDNYPQFSE+ Y V V ED+ +  N  + +++ATD D G N+AI Y+I+
Sbjct: 442  TATVYIEVEDENDNYPQFSEQNYVVQVPEDVGL--NTAVLRVQATDRDQGQNAAIHYSIL 499

Query: 193  GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIRDVN 251
             GN   QF + SLSG + ++  LD+E V+ Y L I+AQDGG P   N++ ++ + + DVN
Sbjct: 500  SGNVAGQFYLHSLSGILDVINPLDFEDVQKYSLSIKAQDGGRPPLINSSGVVSVQVLDVN 559

Query: 252  DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD------------- 298
            DN P F +S FQ +V ENVP+GY +V +QA DAD G NA L Y + D             
Sbjct: 560  DNEPIFVSSPFQATVLENVPLGYPVVHIQAVDADSGENARLHYRLVDTASTFLGGGSAGP 619

Query: 299  KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358
            K+     D P  I   SGW+    +LDRE    Y   V A D G PP S++ +       
Sbjct: 620  KNPAPTPDFPFQIHNSSGWITVCAELDREEVEHYSFGVEAVDHGSPPMSSSTSVSITVLD 679

Query: 359  XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQN 418
                   F    YE+ L ED   G+ V+TL A D D ++ + Y++TGGNTR RF+++SQ 
Sbjct: 680  VNDNDPVFTQPTYELRLNEDAAVGSSVLTLQARDRDANSVITYQLTGGNTRNRFALSSQR 739

Query: 419  GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASV 478
            G GLIT+A PLD+KQE++YVL V+A+D G RS TA V IN+TDAN + PVF+++ YT SV
Sbjct: 740  GGGLITLALPLDYKQEQQYVLAVTASD-GTRSHTAHVLINVTDANTHRPVFQSSHYTVSV 798

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             ED P+GT++  +SA D D G NA+ITY +   +          QF I+P +G + T   
Sbjct: 799  SEDRPVGTSIATLSANDEDTGENARITYVIQDPVP---------QFRIDPDSGTMYTMME 849

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            LD E    Y LT+ A+D G+P  SDTT +EI ++D NDN P F    Y  +I EDA   T
Sbjct: 850  LDYENQVAYTLTIMAQDNGIPQKSDTTTLEILILDANDNAPQFLWDFYQGSIFEDAPPST 909

Query: 599  SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
            S+ QV ATD D G NGR+ Y     D  +G F I+P SGVIRT + LDRE+VA ++L A+
Sbjct: 910  SILQVSATDRDSGPNGRLLYTFQGGDDGDGDFYIEPTSGVIRTQRRLDRENVAVYNLWAL 969

Query: 659  AIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
            A+D G+P P S++V + + I DIND+ P+FE D L  ++ EN+P+G+ + +IRA+DPDEG
Sbjct: 970  AVDRGSPTPLSASVEIQVTILDINDNAPMFEKDELELFVEENNPVGSVVAKIRANDPDEG 1029

Query: 718  PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND 777
            PNA + Y I  GD  + F L+   G    +L  MV+LD+E  R++Y LV++A S PL + 
Sbjct: 1030 PNAQIMYQIVEGDMRHFFQLDLLNG----DLRAMVELDFEV-RREYVLVVQATSAPLVSR 1084

Query: 778  VRVEILVTDVNDNAPVMKDFQIIFNNY----KDCFPVGPFGRVPAYDADVTDKLQYRILS 833
              V IL+ D NDN PV+ DFQI+FNNY     + FP G  G +PA+D DV+D L Y  + 
Sbjct: 1085 ATVHILLVDQNDNPPVLPDFQILFNNYVTNKSNSFPTGVIGCIPAHDPDVSDSLNYTFVQ 1144

Query: 834  GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLL 893
            GN   L+LL+  TG + LS  L+ N P  A MEVSV+DG++ + A   L V +IT++ML 
Sbjct: 1145 GNELRLLLLDPATGELQLSRDLDNNRPLEALMEVSVSDGIHSVTAFCTLRVTIITDDMLT 1204

Query: 894  NSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSA 953
            NSITVRL +M+ E+FLSPLL  F++G+AA++   K+++++F+VQ+DTDV+ NILNV+FSA
Sbjct: 1205 NSITVRLENMSQEKFLSPLLALFVEGVAAVLSTTKDDVFVFNVQNDTDVSSNILNVTFSA 1264

Query: 954  RRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEEC 1013
              P    GV G     +    L+E++YL+RT L  ++T +VLPFDDNIC+ EPC N+ +C
Sbjct: 1265 LLPG---GVRGQ---FFPSEDLQEQIYLNRTLLTTISTQRVLPFDDNICLREPCENYMKC 1318

Query: 1014 LTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSIC 1073
            ++VL+F +++ F++S +VLFRPI+P+    C+CP GFTG  CET +     +  G    C
Sbjct: 1319 VSVLRFDSSAPFLSSTTVLFRPIHPINGLRCRCPPGFTGDYCETEIDLCYSDPCGANGRC 1378

Query: 1074 RSGSQCVARREGGILCQGCSIDAAYTTAVCELRARS 1109
            RS       REGG  C+ C  D  +T   CE+ ARS
Sbjct: 1379 RS-------REGGYTCE-CFED--FTGEHCEVDARS 1404



 Score =  591 bits (1460), Expect = e-167
 Identities = 319/903 (35%), Positives = 479/903 (53%), Gaps = 84/903 (9%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            +TC+C E FTG +CE       C       +C++G  CV    GG  C  C     Y   
Sbjct: 1385 YTCECFEDFTGEHCEVDARSGRCA----NGVCKNGGTCVNLLIGGFHCV-CP-PGEYERP 1438

Query: 1102 VCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVS 1161
             CE+  RSFP  SF+TF GL++R    + L FATQ  +GLLLYNGR+NE+HDF+ALE+V 
Sbjct: 1439 YCEVTTRSFPPQSFVTFRGLRQRFHFTISLTFATQERNGLLLYNGRFNEKHDFIALEIVD 1498

Query: 1162 SEAGRGGGPGLRFSFSLGGGKSEIT--VEGNVGDGSWHTVEIEYFNRT------------ 1207
             +        ++ +FS G   + +   V   V DG WH+V+++Y+N+             
Sbjct: 1499 EQ--------VQLTFSAGETTTTVAPKVPSGVSDGRWHSVQVQYYNKPNIGHLGLPHGPS 1550

Query: 1208 ----ITMILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTET-CHRFLDLTGPL 1262
                  + +DDCD  +++    D G  Y+CA              T+T   + LDLTGPL
Sbjct: 1551 GEKMAVVTVDDCDTTMAVRFGKDIG-NYSCA-----------AQGTQTGSKKSLDLTGPL 1598

Query: 1263 QIGGLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPC 1322
             +GG+PN+P  F V N+ FVGC+ +  +D K +D+  ++A+NGT  GC  +R+ C    C
Sbjct: 1599 LLGGVPNLPEDFPVHNRQFVGCMRNLSVDGKNVDMAGFIANNGTREGCAARRNFCDGRRC 1658

Query: 1323 YNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLRPIQLPWLNALS 1382
             NG  C + W+ Y+C+C     GK+C  +   P  F G+ ++S++ L   I +PW   L 
Sbjct: 1659 QNGGTCVNRWNMYLCECPLRFGGKNCEQAMPHPQLFSGESVVSWSDLNIIISVPWYLGLM 1718

Query: 1383 IRTRQRDAFVMS----------IQLKSGLLHYSYNG-----ETMYLPMATLSDGAWHR-- 1425
             RTR+ D+ +M           +Q+ +  L +  +      E++ L    ++DG WH   
Sbjct: 1719 FRTRKEDSVLMEATSGGPTSFRLQILNNYLQFEVSHGPSDVESVMLSGLRVTDGEWHHLL 1778

Query: 1426 IEIKWLGTD------ISVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGLLASDV 1479
            IE+K +  D      +++T+DYG+       +   + G  +  +++GG       +    
Sbjct: 1779 IELKNVKEDSEMKHLVTMTLDYGMDQNKAD-IGGMLPGLTVRSVVVGGASEDKVSVRRG- 1836

Query: 1480 GFFEGCIQDVRIG---TAQSLLN-RPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSS 1535
              F GC+Q VR+G   T  + LN    ++  V+DGC     C  S CPP S+C  +W+  
Sbjct: 1837 --FRGCMQGVRMGGTPTNVATLNMNNALKVRVKDGCDVDDPCTSSPCPPNSRCHDAWEDY 1894

Query: 1536 TCTCEAGRVGPQCVSACELGPC-GAARCVPDQ-TPKGYSCACEPGYTLTTSGCIESGKEE 1593
            +C C+ G +G  CV AC L PC     CV    +P+GY C C P +      C       
Sbjct: 1895 SCVCDKGYLGINCVDACHLNPCENMGACVRSPGSPQGYVCECGPSHY--GPYCENKLDLP 1952

Query: 1594 CPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSEN 1653
            CP GWWG   CGPC C V++G+ P CNK NG+C CKEN+YK      CLPC C+  GS +
Sbjct: 1953 CPRGWWGNPVCGPCHCAVSKGFDPDCNKTNGQCQCKENYYKLLAQDTCLPCDCFPHGSHS 2012

Query: 1654 SSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFG 1713
             +C+ ATGQC C+PGVIGR C+ C N +AEVT   GCEV+Y+GCP++F  G+WWP+TKFG
Sbjct: 2013 RTCDMATGQCACKPGVIGRQCNRCDNPFAEVT-TLGCEVIYNGCPKAFEAGIWWPQTKFG 2071

Query: 1714 VETITDCPPGSSGRATRTCDETKDVPWQDPDMFNCTTATFYQLRKQLHKIETGELTMNTF 1773
                  CP GS G A R C   K   W  P++FNCTT +F  LR    K+   E  ++  
Sbjct: 2072 QPAAVPCPKGSVGNAVRHCSGEKG--WLPPELFNCTTISFVDLRAMNEKLSRNETQVDGA 2129

Query: 1774 VGVRVAADLSTACANTPRLYGADVVVAEGILLELMDYELRQAGLNLTHSQDKDYVRNLLK 1833
              +++   L +A  +T  L+G DV  A  +L  ++ +E  Q G +L  +QD D+  +++ 
Sbjct: 2130 RALQLVRALRSATQHTGTLFGNDVRTAYQLLGHVLQHESWQQGFDLAATQDADFHEDVIH 2189

Query: 1834 STNTILNVEYEREWKRIRELTGHGAELLVQKFDEYIAVLAESQHDTYTSPFEIVTKDVVI 1893
            S + +L       W++I+   G  A+LL ++ + Y + +A +   TY  PF IVT ++++
Sbjct: 2190 SGSALLAPATRAAWEQIQRSEGGTAQLL-RRLEGYFSNVARNVRRTYLRPFVIVTANMIL 2248

Query: 1894 SVD 1896
            +VD
Sbjct: 2249 AVD 2251



 Score =  348 bits (856), Expect = 1e-93
 Identities = 278/877 (31%), Positives = 418/877 (47%), Gaps = 73/877 (8%)

Query: 23   FEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXX 82
            F M  Y+ ++ E   +GT +L L A     G+   V Y +E      L  E +       
Sbjct: 245  FPMPNYQVALFENEPAGTLILQLHAHYTIEGEEERVSYYME-----GLFDERS------- 292

Query: 83   XXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIID 142
                +  FRID  +GA+ T + LDRE    + + VKA D ++P     S+T  I V + D
Sbjct: 293  ----RGYFRIDSATGAVSTDSVLDRETKETHVLRVKAVDYSTPPR---SATTYITVLVKD 345

Query: 143  DNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI 202
             ND+ P F +  Y   V E++ V     +  I+A+D D   N+ +RY ++GG   + F +
Sbjct: 346  TNDHSPVFEQSEYRERVRENLEV--GYEVLTIRASDRDSPINANLRYRVLGGAWDV-FQL 402

Query: 203  DSLSGDVSLVKTLDYEQVRSYRLVIRAQD-GGSPS-RSNTTQLLINIRDVNDNAPRFYTS 260
            +  SG VS    LD E+   Y+L++ A D G +P   S T  + I + D NDN P+F   
Sbjct: 403  NESSGVVSTRAVLDREEAAEYQLLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQ 462

Query: 261  LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT 320
             +   V E+V +  +++RVQA D D+G NA + Y++     +GNV     +   SG +  
Sbjct: 463  NYVVQVPEDVGLNTAVLRVQATDRDQGQNAAIHYSI----LSGNVAGQFYLHSLSGILDV 518

Query: 321  SGQLDRETQAKYQLLVTATDGGDPPR-SATATXXXXXXXXXXXXXXFMPGQYEVELAEDE 379
               LD E   KY L + A DGG PP  +++                F+   ++  + E+ 
Sbjct: 519  INPLDFEDVQKYSLSIKAQDGGRPPLINSSGVVSVQVLDVNDNEPIFVSSPFQATVLENV 578

Query: 380  PPGTPVVTLTATDAD--EDNRLHYEIT-------GGNTRG--------RFSITSQNGRGL 422
            P G PVV + A DAD  E+ RLHY +        GG + G         F     N  G 
Sbjct: 579  PLGYPVVHIQAVDADSGENARLHYRLVDTASTFLGGGSAGPKNPAPTPDFPFQIHNSSGW 638

Query: 423  ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480
            ITV   LD ++   Y   V A D G    S +  V I + D N+  PVF    Y   + E
Sbjct: 639  ITVCAELDREEVEHYSFGVEAVDHGSPPMSSSTSVSITVLDVNDNDPVFTQPTYELRLNE 698

Query: 481  DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
            DA +G++VL + A D D   N+ ITY L+   +    A   Q+       G IT    LD
Sbjct: 699  DAAVGSSVLTLQARDRDA--NSVITYQLTGGNTRNRFALSSQR-----GGGLITLALPLD 751

Query: 541  RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
             +    Y+L VTA DG   + S T  V I+V D N + PVF+   YT ++ ED  VGTS+
Sbjct: 752  YKQEQQYVLAVTASDG---TRSHTAHVLINVTDANTHRPVFQSSHYTVSVSEDRPVGTSI 808

Query: 601  SQVGATDADVGLNGRIHYEL-DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
            + + A D D G N RI Y + DP  +    F IDP SG + T   LD E+   + L  +A
Sbjct: 809  ATLSANDEDTGENARITYVIQDPVPQ----FRIDPDSGTMYTMMELDYENQVAYTLTIMA 864

Query: 660  IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
             D G P +S T  + I I D ND+ P F  D     I E++P  T+I ++ A D D GPN
Sbjct: 865  QDNGIPQKSDTTTLEILILDANDNAPQFLWDFYQGSIFEDAPPSTSILQVSATDRDSGPN 924

Query: 720  AVVHYSIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP-PLWND 777
              + Y+ +GGDD +  F +E   G  + +    +D +  +    + L +   SP PL   
Sbjct: 925  GRLLYTFQGGDDGDGDFYIEPTSGVIRTQ--RRLDRENVAVYNLWALAVDRGSPTPLSAS 982

Query: 778  VRVEILVTDVNDNAPVM-KDFQIIFNNYKDCFPVGP-FGRVPAYDAD--VTDKLQYRILS 833
            V +++ + D+NDNAP+  KD   +F   ++  PVG    ++ A D D     ++ Y+I+ 
Sbjct: 983  VEIQVTILDINDNAPMFEKDELELF--VEENNPVGSVVAKIRANDPDEGPNAQIMYQIVE 1040

Query: 834  GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVT 870
            G+  +   L+   G +    +L+  V +   + V  T
Sbjct: 1041 GDMRHFFQLDLLNGDLRAMVELDFEVRREYVLVVQAT 1077



 Score =  310 bits (761), Expect = 4e-82
 Identities = 246/776 (31%), Positives = 379/776 (48%), Gaps = 78/776 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND+ P F  Q Y   V E     T VL ++ATD+D G+NA + Y+I        
Sbjct: 447  IEVEDENDNYPQFSEQNYVVQVPEDVGLNTAVLRVQATDRDQGQNAAIHYSI-------- 498

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           V   F +   SG L     LD E V +Y++ +KA D   P    +
Sbjct: 499  -----------LSGNVAGQFYLHSLSGILDVINPLDFEDVQKYSLSIKAQDGGRP--PLI 545

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +S+  + V ++D NDN P F    +  +V E++ +   PV+  I+A DAD G N+ + Y 
Sbjct: 546  NSSGVVSVQVLDVNDNEPIFVSSPFQATVLENVPL-GYPVV-HIQAVDADSGENARLHYR 603

Query: 191  II-------GGNT----------QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233
            ++       GG +             F I + SG +++   LD E+V  Y   + A D G
Sbjct: 604  LVDTASTFLGGGSAGPKNPAPTPDFPFQIHNSSGWITVCAELDREEVEHYSFGVEAVDHG 663

Query: 234  SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293
            SP  S++T + I + DVNDN P F    ++  ++E+  +G S++ +QA D D   N+ +T
Sbjct: 664  SPPMSSSTSVSITVLDVNDNDPVFTQPTYELRLNEDAAVGSSVLTLQARDRD--ANSVIT 721

Query: 294  YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353
            Y +T  + T N    ++     G +  +  LD + + +Y L VTA+DG    RS TA   
Sbjct: 722  YQLTGGN-TRN-RFALSSQRGGGLITLALPLDYKQEQQYVLAVTASDG---TRSHTAHVL 776

Query: 354  XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGR 411
                        F    Y V ++ED P GT + TL+A D D  E+ R+ Y I   +   +
Sbjct: 777  INVTDANTHRPVFQSSHYTVSVSEDRPVGTSIATLSANDEDTGENARITYVIQ--DPVPQ 834

Query: 412  FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVF 469
            F I   +G  + T+ + LD++ +  Y LT+ A D+G   +SDT  ++I I DAN+ AP F
Sbjct: 835  FRIDPDSGT-MYTMME-LDYENQVAYTLTIMAQDNGIPQKSDTTTLEILILDANDNAPQF 892

Query: 470  ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
                Y  S+FEDAP  T++L VSATD D G N ++ Y+             D  F I P 
Sbjct: 893  LWDFYQGSIFEDAPPSTSILQVSATDRDSGPNGRLLYTFQGGDDG------DGDFYIEPT 946

Query: 530  TGAITTNKLLDRETMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTA 588
            +G I T + LDRE ++ Y L   A D G P+ LS + +++++++D+NDN P+F++     
Sbjct: 947  SGVIRTQRRLDRENVAVYNLWALAVDRGSPTPLSASVEIQVTILDINDNAPMFEKDELEL 1006

Query: 589  NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648
             + E+  VG+ V+++ A D D G N +I Y++   D     F +D  +G +R    LD E
Sbjct: 1007 FVEENNPVGSVVAKIRANDPDEGPNAQIMYQIVEGDMRH-FFQLDLLNGDLRAMVELDFE 1065

Query: 649  SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF--YISENS---PIG 703
                +    + +   + P  S   VHI + D ND+PPV     + F  Y++  S   P G
Sbjct: 1066 VRREY---VLVVQATSAPLVSRATVHILLVDQNDNPPVLPDFQILFNNYVTNKSNSFPTG 1122

Query: 704  TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759
              IG I AHDPD   +  ++Y+   G++     L+   G    EL    DLD   P
Sbjct: 1123 -VIGCIPAHDPDVSDS--LNYTFVQGNELRLLLLDPATG----ELQLSRDLDNNRP 1171



 Score =  289 bits (708), Expect = 1e-75
 Identities = 219/683 (32%), Positives = 332/683 (48%), Gaps = 46/683 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + VLD ND+ P+F    ++A+V E    G  V+ ++A D D G+NA + Y +    +  L
Sbjct: 553  VQVLDVNDNEPIFVSSPFQATVLENVPLGYPVVHIQAVDADSGENARLHYRLVDTASTFL 612

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                A              F+I   SG +   A LDRE+V  Y+  V+A D  SP    +
Sbjct: 613  GGGSAGPKNPAPTPDFP--FQIHNSSGWITVCAELDREEVEHYSFGVEAVDHGSP---PM 667

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            SS+ ++ + ++D NDN P F++ TY + ++ED +V  +  +  ++A D D  ANS I Y 
Sbjct: 668  SSSTSVSITVLDVNDNDPVFTQPTYELRLNEDAAVGSS--VLTLQARDRD--ANSVITYQ 723

Query: 191  IIGGNTQMQFSIDSLSGD--VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            + GGNT+ +F++ S  G   ++L   LDY+Q + Y L + A DG   +RS+T  +LIN+ 
Sbjct: 724  LTGGNTRNRFALSSQRGGGLITLALPLDYKQEQQYVLAVTASDG---TRSHTAHVLINVT 780

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            D N + P F +S +  SVSE+ P+G SI  + A D D G NA +TY + D        +P
Sbjct: 781  DANTHRPVFQSSHYTVSVSEDRPVGTSIATLSANDEDTGENARITYVIQD-------PVP 833

Query: 309  -ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
               IDP SG +YT  +LD E Q  Y L + A D G P +S T T              F+
Sbjct: 834  QFRIDPDSGTMYTMMELDYENQVAYTLTIMAQDNGIPQKSDTTTLEILILDANDNAPQFL 893

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNT-RGRFSITSQNGRGLIT 424
               Y+  + ED PP T ++ ++ATD D   + RL Y   GG+   G F I   +  G+I 
Sbjct: 894  WDFYQGSIFEDAPPSTSILQVSATDRDSGPNGRLLYTFQGGDDGDGDFYIEPTS--GVIR 951

Query: 425  VAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFED 481
              + LD +    Y L   A D G     S +  +Q+ I D N+ AP+FE       V E+
Sbjct: 952  TQRRLDRENVAVYNLWALAVDRGSPTPLSASVEIQVTILDINDNAPMFEKDELELFVEEN 1011

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
             P+G+ V  + A D D G NAQI Y    +I    + H  Q  ++N    A+     LD 
Sbjct: 1012 NPVGSVVAKIRANDPDEGPNAQIMY----QIVEGDMRHFFQLDLLNGDLRAMVE---LDF 1064

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ-QLYTANIMEDALVGTSV 600
            E    Y+L V A     P +S  T V I +VD NDN PV    Q+   N + +       
Sbjct: 1065 EVRREYVLVVQAT--SAPLVSRAT-VHILLVDQNDNPPVLPDFQILFNNYVTNKSNSFPT 1121

Query: 601  SQVGATDA-DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
              +G   A D  ++  ++Y    +  E    ++DPA+G ++ ++ LD        L  V+
Sbjct: 1122 GVIGCIPAHDPDVSDSLNYTF-VQGNELRLLLLDPATGELQLSRDLDNNR-PLEALMEVS 1179

Query: 660  IDGGTPPQSSTVIVHIKIEDIND 682
            +  G    S T    +++  I D
Sbjct: 1180 VSDGI--HSVTAFCTLRVTIITD 1200



 Score =  177 bits (430), Expect = 5e-42
 Identities = 139/457 (30%), Positives = 208/457 (45%), Gaps = 38/457 (8%)

Query: 8    HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
            H  INV D N H PVF+   Y  SV E    GT++ TL A D+D G+NA + Y I+    
Sbjct: 774  HVLINVTDANTHRPVFQSSHYTVSVSEDRPVGTSIATLSANDEDTGENARITYVIQ---- 829

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
            D + P+                FRID  SG + T   LD E    YT+ + A D   P  
Sbjct: 830  DPV-PQ----------------FRIDPDSGTMYTMMELDYENQVAYTLTIMAQDNGIP-- 870

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
             + S T T+ + I+D NDN PQF    Y  S+ ED   + +  I ++ ATD D G N  +
Sbjct: 871  -QKSDTTTLEILILDANDNAPQFLWDFYQGSIFEDAPPSTS--ILQVSATDRDSGPNGRL 927

Query: 188  RYAIIGGNT-QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLI 245
             Y   GG+     F I+  SG +   + LD E V  Y L   A D GSP+  S + ++ +
Sbjct: 928  LYTFQGGDDGDGDFYIEPTSGVIRTQRRLDRENVAVYNLWALAVDRGSPTPLSASVEIQV 987

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
             I D+NDNAP F     +  V EN P+G  + +++A D DEG NA++ Y + +    G++
Sbjct: 988  TILDINDNAPMFEKDELELFVEENNPVGSVVAKIRANDPDEGPNAQIMYQIVE----GDM 1043

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
                 +D  +G +    +LD E + +Y L+V AT      R+                  
Sbjct: 1044 RHFFQLDLLNGDLRAMVELDFEVRREYVLVVQATSAPLVSRATVHILLVDQNDNPPVLPD 1103

Query: 366  F--MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423
            F  +   Y    +   P G  +  + A D D  + L+Y    GN      +    G   +
Sbjct: 1104 FQILFNNYVTNKSNSFPTGV-IGCIPAHDPDVSDSLNYTFVQGNELRLLLLDPATGE--L 1160

Query: 424  TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT 460
             +++ LD  +    ++ VS +D G  S TA   + +T
Sbjct: 1161 QLSRDLDNNRPLEALMEVSVSD-GIHSVTAFCTLRVT 1196



 Score =  112 bits (270), Expect = 1e-22
 Identities = 91/301 (30%), Positives = 136/301 (45%), Gaps = 15/301 (4%)

Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP--KDREEGSFVIDPASGV 638
           F    Y   + E+   GT + Q+ A     G   R+ Y ++    +R  G F ID A+G 
Sbjct: 245 FPMPNYQVALFENEPAGTLILQLHAHYTIEGEEERVSYYMEGLFDERSRGYFRIDSATGA 304

Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698
           + T+  LDRE+  TH L+  A+D  TPP+S+T  + + ++D ND  PVFE       + E
Sbjct: 305 VSTDSVLDRETKETHVLRVKAVDYSTPPRSATTYITVLVKDTNDHSPVFEQSEYRERVRE 364

Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758
           N  +G  +  IRA D D   NA + Y + GG   + F L    G     + T   LD E 
Sbjct: 365 NLEVGYEVLTIRASDRDSPINANLRYRVLGG-AWDVFQLNESSG----VVSTRAVLDREE 419

Query: 759 PRKKYELVIRA----ASP-PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF 813
              +Y+L++ A     +P PL     V I V D NDN P   +   +    +D       
Sbjct: 420 -AAEYQLLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNYVVQVPEDVGLNTAV 478

Query: 814 GRVPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            RV A D D      + Y ILSGN A    L+  +G + +   L+    +  ++ +   D
Sbjct: 479 LRVQATDRDQGQNAAIHYSILSGNVAGQFYLHSLSGILDVINPLDFEDVQKYSLSIKAQD 538

Query: 872 G 872
           G
Sbjct: 539 G 539



 Score = 68.5 bits (160), Expect = 2e-09
 Identities = 47/151 (31%), Positives = 78/151 (51%), Gaps = 14/151 (9%)

Query: 2173 GIRLKKPIRLQIWLDINRETFGSRTNPQCVHWS---TLRGSGEWSRVGCHTEIDYDWSPY 2229
            G  L +P+   + ++        RT P CV W+    + G+G WS  GC           
Sbjct: 2383 GAPLPRPLERPVLVEFALLEVEERTKPVCVFWNHSLAVGGTGGWSARGCEL--------L 2434

Query: 2230 SEEPLLINCTCNHLSTFAVLVDEVDVEFIPEPSLLESVTSYTAFSISLPLLLTSWAALCL 2289
            S     + C C+H ++FAVL+D +      E   L+ VT Y A S+SL  LL ++  L L
Sbjct: 2435 SRNRTHVACQCSHTASFAVLMD-ISRRENGEVLPLKIVT-YAAVSLSLAALLVAFVLLSL 2492

Query: 2290 IRGGAATVSNSIHKHLIFSVFMAELLYLIAL 2320
            +R   + + +SIHKHL  ++F+++L+++I +
Sbjct: 2493 VRMLRSNL-HSIHKHLAVALFLSQLVFVIGI 2522


>UniRef50_Q9NYQ7 Cluster: Cadherin EGF LAG seven-pass G-type receptor
            3 precursor; n=60; Eukaryota|Rep: Cadherin EGF LAG
            seven-pass G-type receptor 3 precursor - Homo sapiens
            (Human)
          Length = 3312

 Score =  903 bits (2234), Expect = 0.0
 Identities = 477/1085 (43%), Positives = 665/1085 (61%), Gaps = 52/1085 (4%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V D NDHSPVFE  QY  ++RE    G  +L L+ATD D   NA + Y         +
Sbjct: 421  VTVADRNDHSPVFEQAQYRETLRENVEEGYPILQLRATDGDAPPNANLRYRF-------V 473

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             P  A              F ID RSG + T   +DRE +  Y ++V+A+DQ      R 
Sbjct: 474  GPPAARAAAAAA-------FEIDPRSGLISTSGRVDREHMESYELVVEASDQGQEPGPR- 525

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S+T  +H+ ++D+NDN PQFSEK Y   V ED  V  + V+ ++ ATD D  AN  + Y 
Sbjct: 526  SATVRVHITVLDENDNAPQFSEKRYVAQVRED--VRPHTVVLRVTATDRDKDANGLVHYN 583

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIRD 249
            II GN++  F+IDSL+G++ +V  LD+E  R Y L IRAQD G P  SN T L  I + D
Sbjct: 584  IISGNSRGHFAIDSLTGEIQVVAPLDFEAEREYALRIRAQDAGRPPLSNNTGLASIQVVD 643

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            +ND+ P F ++ FQ SV EN P+G+S++ +QA DAD G NA L Y++T        D P 
Sbjct: 644  INDHIPIFVSTPFQVSVLENAPLGHSVIHIQAVDADHGENARLEYSLTGVA----PDTPF 699

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             I+  +GWV  SG LDRE+   Y   V A D G PP SA+A+              F   
Sbjct: 700  VINSATGWVSVSGPLDRESVEHYFFGVEARDHGSPPLSASASVTVTVLDVNDNRPEFTMK 759

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
            +Y + L ED   GT VV++TA D D ++ + Y+ITGGNTR RF+I++Q G GL+T+A PL
Sbjct: 760  EYHLRLNEDAAVGTSVVSVTAVDRDANSAISYQITGGNTRNRFAISTQGGVGLVTLALPL 819

Query: 430  DFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
            D+KQER + L ++A+D     D   V INITDAN + PVF++A Y+ SV ED P+G+T++
Sbjct: 820  DYKQERYFKLVLTASDRA-LHDHCYVHINITDANTHRPVFQSAHYSVSVNEDRPMGSTIV 878

Query: 490  VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
            V+SA+D DVG NA+ITY L   +          QF I+  +GAIT    LD E    Y L
Sbjct: 879  VISASDDDVGENARITYLLEDNLP---------QFRIDADSGAITLQAPLDYEDQVTYTL 929

Query: 550  TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
             +TARD G+P  +DTT VE+ V DVNDN P F    YT  + EDA   TSV Q+ ATD D
Sbjct: 930  AITARDNGIPQKADTTYVEVMVNDVNDNAPQFVASHYTGLVSEDAPPFTSVLQISATDRD 989

Query: 610  VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669
               NGR+ Y     +  +G F I+P SG++RT + LDRE+V+ ++L A A+D G PP  +
Sbjct: 990  AHANGRVQYTFQNGEDGDGDFTIEPTSGIVRTVRRLDREAVSVYELTAYAVDRGVPPLRT 1049

Query: 670  TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729
             V + + ++D+ND+ PVF ++     + ENS +G+ + +I A DPDEGPNA + Y I  G
Sbjct: 1050 PVSIQVMVQDVNDNAPVFPAEEFEVRVKENSIVGSVVAQITAVDPDEGPNAHIMYQIVEG 1109

Query: 730  DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVND 789
            +    F ++   G    EL  ++DLDYE+ R++Y +V++A S PL +   V + + D ND
Sbjct: 1110 NIPELFQMDIFSG----ELTALIDLDYEA-RQEYVIVVQATSAPLVSRATVHVRLVDQND 1164

Query: 790  NAPVMKDFQIIFNNY----KDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNET 845
            N+PV+ +FQI+FNNY     D FP G  GR+PAYD DV+D L Y    GN   L+++N+T
Sbjct: 1165 NSPVLNNFQILFNNYVSNRSDTFPSGIIGRIPAYDPDVSDHLFYSFERGNELQLLVVNQT 1224

Query: 846  TGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTA 905
            +G + LS +L+ N P +A+M V+VTDG++ + A   L V +ITEE+L NS+TVRL +M  
Sbjct: 1225 SGELRLSRKLDNNRPLVASMLVTVTDGLHSVTAQCVLRVVIITEELLANSLTVRLENMWQ 1284

Query: 906  EQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRP-DAEVGVAG 964
            E+FLSPLLG F++G+AA++  P E+++IF++Q+DTDV G +LNVSFSA  P  A  G AG
Sbjct: 1285 ERFLSPLLGRFLEGVAAVLATPAEDVFIFNIQNDTDVGGTVLNVSFSALAPRGAGAGAAG 1344

Query: 965  DPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASG 1024
               P +S   L+E++Y+ R  LA  + + VLPFDDN+C+ EPC N+ +C++VL+F +++ 
Sbjct: 1345 ---PWFSSEELQEQLYVRRAALAARSLLDVLPFDDNVCLREPCENYMKCVSVLRFDSSAP 1401

Query: 1025 FVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARRE 1084
            F+ S S LFRPI P+    C+CP GFTG  CET L           + CR+G  C ARRE
Sbjct: 1402 FLASASTLFRPIQPIAGLRCRCPPGFTGDFCETELDLCY------SNPCRNGGAC-ARRE 1454

Query: 1085 GGILC 1089
            GG  C
Sbjct: 1455 GGYTC 1459



 Score =  628 bits (1551), Expect = e-178
 Identities = 348/912 (38%), Positives = 488/912 (53%), Gaps = 84/912 (9%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            +TC C   FTG +CE       C V G   +CR+G  C     GG  CQ C    A+   
Sbjct: 1457 YTCVCRPRFTGEDCELDTEAGRC-VPG---VCRNGGTCTDAPNGGFRCQ-CPAGGAFEGP 1511

Query: 1102 VCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVS 1161
             CE+ ARSFP SSF+ F GL++R  + L L FAT   SGLL YNGR NE+HDFLALELV+
Sbjct: 1512 RCEVAARSFPPSSFVMFRGLRQRFHLTLSLSFATVQQSGLLFYNGRLNEKHDFLALELVA 1571

Query: 1162 SEAGRGGGPGLRFSFSLGGGKSEI--TVEGNVGDGSWHTVEIEYFNRTIT---------- 1209
             +        +R ++S G   + +  TV G + DG WHTV + Y+N+  T          
Sbjct: 1572 GQ--------VRLTYSTGESNTVVSPTVPGGLSDGQWHTVHLRYYNKPRTDALGGAQGPS 1623

Query: 1210 ------MILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQ 1263
                  + +DDCD  ++L   A+ G  Y+C         A   + T +  + LDLTGPL 
Sbjct: 1624 KDKVAVLSVDDCDVAVALQFGAEIG-NYSC---------AAAGVQTSS-KKSLDLTGPLL 1672

Query: 1264 IGGLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCY 1323
            +GG+PN+P +F V +KDF+GC+ D +ID + +D+ ++VA+NGT+AGC  K   C S PC 
Sbjct: 1673 LGGVPNLPENFPVSHKDFIGCMRDLHIDGRRVDMAAFVANNGTMAGCQAKLHFCDSGPCK 1732

Query: 1324 NGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFN-PLLRPIQLPWLNALS 1382
            N   CS+ W ++ CDC  G  GKDC  +   P  F G+G LS+N      + +PW   L+
Sbjct: 1733 NSGFCSERWGSFSCDCPVGFGGKDCQLTMAHPHHFRGNGTLSWNFGSDMAVSVPWYLGLA 1792

Query: 1383 IRTRQRDAFVMSI----------QLKSGLLHY-----SYNGETMYLPMATLSDGAWH--R 1425
             RTR     +M +          QL  GLL       S     + L   T+SDG WH  R
Sbjct: 1793 FRTRATQGVLMQVQAGPHSTLLCQLDRGLLSVTVTRGSGRASHLLLDQVTVSDGRWHDLR 1852

Query: 1426 IEIK-----WLGTDI-SVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGLLASDV 1479
            +E++       G  +  V++D+ L    M  + +++QG  + ++ +GGL   +   A   
Sbjct: 1853 LELQEEPGGRRGHHVLMVSLDFSLFQDTM-AVGSELQGLKVKQLHVGGLPPGSAEEAPQ- 1910

Query: 1480 GFFEGCIQDVRIGTAQS---LLNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSST 1536
            G   GCIQ V +G+  S    L  P+ R N   GC     C    CPP++ C   W + +
Sbjct: 1911 GLV-GCIQGVWLGSTPSGSPALLPPSHRVNAEPGCVVTNACASGPCPPHADCRDLWQTFS 1969

Query: 1537 CTCEAGRVGPQCVSACELGPC---GAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEE 1593
            CTC+ G  GP CV AC L PC   G+ R +P   P GY+C C  GY      C     ++
Sbjct: 1970 CTCQPGYYGPGCVDACLLNPCQNQGSCRHLPG-APHGYTCDCVGGY--FGHHCEHRMDQQ 2026

Query: 1594 CPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSEN 1653
            CP GWWG   CGPC CDV +G+ P+CNK NG+CHCKE HY+P G+  CLPC CY  GS +
Sbjct: 2027 CPRGWWGSPTCGPCNCDVHKGFDPNCNKTNGQCHCKEFHYRPRGSDSCLPCDCYPVGSTS 2086

Query: 1654 SSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFG 1713
             SC   +GQC CRPG +GR C++C + +AEVT  SGC V+YD CP+S   GVWWP+TKFG
Sbjct: 2087 RSCAPHSGQCPCRPGALGRQCNSCDSPFAEVTA-SGCRVLYDACPKSLRSGVWWPQTKFG 2145

Query: 1714 VETITDCPPGSSGRATRTCDETKDVPWQDPDMFNCTTATFYQLRKQLHKIETGELTMNTF 1773
            V     CP G+ G A R CDE +   W +PD+FNCT+  F +L   L  +E  +  ++T 
Sbjct: 2146 VLATVPCPRGALGAAVRLCDEAQG--WLEPDLFNCTSPAFRELSLLLDGLELNKTALDTM 2203

Query: 1774 VGVRVAADLSTACANTPRLYGADVVVAEGILLELMDYELRQAGLNLTHSQDKDYVRNLLK 1833
               ++A  L     +T   +  DV V   +L  L+ +E  Q G  LT +QD  +  NLL 
Sbjct: 2204 EAKKLAQRLREVTGHTDHYFSQDVRVTARLLAHLLAFESHQQGFGLTATQDAHFNENLLW 2263

Query: 1834 STNTILNVEYEREWKRIRELT---GHGAELLVQKFDEYIAVLAESQHDTYTSPFEIVTKD 1890
            + + +L  E    W  + +       G+  LV+  +EY A LA +   TY +P  +VT +
Sbjct: 2264 AGSALLAPETGDLWAALGQRAPGGSPGSAGLVRHLEEYAATLARNMELTYLNPMGLVTPN 2323

Query: 1891 VVISVDTVTSES 1902
            +++S+D +   S
Sbjct: 2324 IMLSIDRMEHPS 2335



 Score =  355 bits (872), Expect = 1e-95
 Identities = 255/807 (31%), Positives = 390/807 (48%), Gaps = 42/807 (5%)

Query: 145  DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY---AIIGGNTQMQFS 201
            + +PQF +  Y   V E+ +      + ++ A D D G    + Y   A++   +   FS
Sbjct: 320  NRHPQFPQYNYQTLVPENEAA--GTAVLRVVAQDPDAGEAGRLVYSLAALMNSRSLELFS 377

Query: 202  IDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261
            ID  SG +     LD E +  + L + AQD GSP  S TT + + + D ND++P F  + 
Sbjct: 378  IDPQSGLIRTAAALDRESMERHYLRVTAQDHGSPRLSATTMVAVTVADRNDHSPVFEQAQ 437

Query: 262  FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT-GNVDLPITIDPRSGWVYT 320
            ++E++ ENV  GY I++++A D D   NA L Y                 IDPRSG + T
Sbjct: 438  YRETLRENVEEGYPILQLRATDGDAPPNANLRYRFVGPPAARAAAAAAFEIDPRSGLIST 497

Query: 321  SGQLDRETQAKYQLLVTATD-GGDP-PRSATATXXXXXXXXXXXXXXFMPGQYEVELAED 378
            SG++DRE    Y+L+V A+D G +P PRSAT                F   +Y  ++ ED
Sbjct: 498  SGRVDREHMESYELVVEASDQGQEPGPRSATVRVHITVLDENDNAPQFSEKRYVAQVRED 557

Query: 379  EPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436
              P T V+ +TATD D+D    +HY I  GN+RG F+I S  G   I V  PLDF+ ER 
Sbjct: 558  VRPHTVVLRVTATDRDKDANGLVHYNIISGNSRGHFAIDSLTGE--IQVVAPLDFEAERE 615

Query: 437  YVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
            Y L + A D+G     ++T +  I + D N++ P+F + P+  SV E+AP+G +V+ + A
Sbjct: 616  YALRIRAQDAGRPPLSNNTGLASIQVVDINDHIPIFVSTPFQVSVLENAPLGHSVIHIQA 675

Query: 494  TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553
             D+D G NA++ YSL+       VA  D  FVIN  TG ++ +  LDRE++  Y   V A
Sbjct: 676  VDADHGENARLEYSLT------GVA-PDTPFVINSATGWVSVSGPLDRESVEHYFFGVEA 728

Query: 554  RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613
            RD G P LS +  V ++V+DVNDN P F  + Y   + EDA VGTSV  V A D D   N
Sbjct: 729  RDHGSPPLSASASVTVTVLDVNDNRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRDA--N 786

Query: 614  GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673
              I Y++         F I    GV     AL  +       K V +            V
Sbjct: 787  SAISYQI-TGGNTRNRFAISTQGGVGLVTLALPLDYKQERYFKLV-LTASDRALHDHCYV 844

Query: 674  HIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN 733
            HI I D N   PVF+S   +  ++E+ P+G+TI  I A D D G NA + Y ++  D+  
Sbjct: 845  HINITDANTHRPVFQSAHYSVSVNEDRPMGSTIVVISASDDDVGENARITYLLE--DNLP 902

Query: 734  SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDN 790
             F ++    +D   +     LDYE  +  Y L I A     P   +   VE++V DVNDN
Sbjct: 903  QFRID----ADSGAITLQAPLDYED-QVTYTLAITARDNGIPQKADTTYVEVMVNDVNDN 957

Query: 791  APVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNAN-LILLNETTG 847
            AP            +D  P     ++ A D D     ++QY   +G + +    +  T+G
Sbjct: 958  APQFVASHYTGLVSEDAPPFTSVLQISATDRDAHANGRVQYTFQNGEDGDGDFTIEPTSG 1017

Query: 848  SMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAE 906
             +    +L+     +  +     D GV  ++    +S++++ +++  N+      +    
Sbjct: 1018 IVRTVRRLDREAVSVYELTAYAVDRGVPPLRT--PVSIQVMVQDVNDNAPVFPAEEFEVR 1075

Query: 907  QFLSPLLGFFIDGLAAIIPCPKENIYI 933
               + ++G  +  + A+ P    N +I
Sbjct: 1076 VKENSIVGSVVAQITAVDPDEGPNAHI 1102



 Score =  343 bits (843), Expect = 4e-92
 Identities = 272/912 (29%), Positives = 428/912 (46%), Gaps = 69/912 (7%)

Query: 17   NDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAX 76
            N H P F    Y+  V E  ++GT VL + A D D G+   + Y++    A  +N     
Sbjct: 320  NRH-PQFPQYNYQTLVPENEAAGTAVLRVVAQDPDAGEAGRLVYSL----AALMNSRSL- 373

Query: 77   XXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATI 136
                       ++F ID +SG + T A+LDRE + R+ + V A D  SP   RLS+T  +
Sbjct: 374  -----------ELFSIDPQSGLIRTAAALDRESMERHYLRVTAQDHGSP---RLSATTMV 419

Query: 137  HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG--- 193
             V + D ND+ P F +  Y  ++ E  +V +   I +++ATD D   N+ +RY  +G   
Sbjct: 420  AVTVADRNDHSPVFEQAQYRETLRE--NVEEGYPILQLRATDGDAPPNANLRYRFVGPPA 477

Query: 194  --GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQLLINIRD 249
                    F ID  SG +S    +D E + SY LV+ A D G     RS T ++ I + D
Sbjct: 478  ARAAAAAAFEIDPRSGLISTSGRVDREHMESYELVVEASDQGQEPGPRSATVRVHITVLD 537

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
             NDNAP+F    +   V E+V     ++RV A D D+  N  + Y +     +GN     
Sbjct: 538  ENDNAPQFSEKRYVAQVREDVRPHTVVLRVTATDRDKDANGLVHYNI----ISGNSRGHF 593

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRS-ATATXXXXXXXXXXXXXXFMP 368
             ID  +G +     LD E + +Y L + A D G PP S  T                F+ 
Sbjct: 594  AIDSLTGEIQVVAPLDFEAEREYALRIRAQDAGRPPLSNNTGLASIQVVDINDHIPIFVS 653

Query: 369  GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
              ++V + E+ P G  V+ + A DAD  E+ RL Y +TG      F I S    G ++V+
Sbjct: 654  TPFQVSVLENAPLGHSVIHIQAVDADHGENARLEYSLTGVAPDTPFVINS--ATGWVSVS 711

Query: 427  QPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
             PLD +    Y   V A D G    S +A V + + D N+  P F    Y   + EDA +
Sbjct: 712  GPLDRESVEHYFFGVEARDHGSPPLSASASVTVTVLDVNDNRPEFTMKEYHLRLNEDAAV 771

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            GT+V+ V+A D D   N+ I+Y ++   +    A   Q  V     G +T    LD +  
Sbjct: 772  GTSVVSVTAVDRDA--NSAISYQITGGNTRNRFAISTQGGV-----GLVTLALPLDYKQE 824

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
              + L +TA D    +L D   V I++ D N + PVF+   Y+ ++ ED  +G+++  + 
Sbjct: 825  RYFKLVLTASD---RALHDHCYVHINITDANTHRPVFQSAHYSVSVNEDRPMGSTIVVIS 881

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            A+D DVG N RI Y L+    +   F ID  SG I     LD E   T+ L   A D G 
Sbjct: 882  ASDDDVGENARITYLLEDNLPQ---FRIDADSGAITLQAPLDYEDQVTYTLAITARDNGI 938

Query: 665  PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
            P ++ T  V + + D+ND+ P F +   T  +SE++P  T++ +I A D D   N  V Y
Sbjct: 939  PQKADTTYVEVMVNDVNDNAPQFVASHYTGLVSEDAPPFTSVLQISATDRDAHANGRVQY 998

Query: 725  SIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEIL 783
            + + G+D +  F++E   G      V  +D +  S  +     +    PPL   V ++++
Sbjct: 999  TFQNGEDGDGDFTIEPTSGI--VRTVRRLDREAVSVYELTAYAVDRGVPPLRTPVSIQVM 1056

Query: 784  VTDVNDNAPVM--KDFQIIFNNYKDCFPVGP-FGRVPAYDAD--VTDKLQYRILSGNNAN 838
            V DVNDNAPV   ++F++     K+   VG    ++ A D D      + Y+I+ GN   
Sbjct: 1057 VQDVNDNAPVFPAEEFEV---RVKENSIVGSVVAQITAVDPDEGPNAHIMYQIVEGNIPE 1113

Query: 839  LILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE---EMLLNS 895
            L  ++  +G +T    L+    +   + V  T     + +   + VRL+ +     +LN+
Sbjct: 1114 LFQMDIFSGELTALIDLDYEARQEYVIVVQATSA--PLVSRATVHVRLVDQNDNSPVLNN 1171

Query: 896  ITVRLNDMTAEQ 907
              +  N+  + +
Sbjct: 1172 FQILFNNYVSNR 1183



 Score =  309 bits (758), Expect = 9e-82
 Identities = 227/734 (30%), Positives = 358/734 (48%), Gaps = 56/734 (7%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            +   I VLD ND++P F  ++Y A VRE     T VL + ATD+D   N  V Y I  ++
Sbjct: 529  VRVHITVLDENDNAPQFSEKRYVAQVREDVRPHTVVLRVTATDRDKDANGLVHYNI--IS 586

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
             ++                 +  F ID  +G +   A LD E    Y + ++A D   P 
Sbjct: 587  GNS-----------------RGHFAIDSLTGEIQVVAPLDFEAEREYALRIRAQDAGRPP 629

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
                ++T    + ++D ND+ P F    + VSV E+  +  +  +  I+A DAD G N+ 
Sbjct: 630  LS--NNTGLASIQVVDINDHIPIFVSTPFQVSVLENAPLGHS--VIHIQAVDADHGENAR 685

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            + Y++ G      F I+S +G VS+   LD E V  Y   + A+D GSP  S +  + + 
Sbjct: 686  LEYSLTGVAPDTPFVINSATGWVSVSGPLDRESVEHYFFGVEARDHGSPPLSASASVTVT 745

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            + DVNDN P F    +   ++E+  +G S+V V A D D   N+ ++Y +T  + T N  
Sbjct: 746  VLDVNDNRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRD--ANSAISYQITGGN-TRN-R 801

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
              I+     G V  +  LD + +  ++L++TA+D                         F
Sbjct: 802  FAISTQGGVGLVTLALPLDYKQERYFKLVLTASDRA---LHDHCYVHINITDANTHRPVF 858

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLIT 424
                Y V + ED P G+ +V ++A+D D  E+ R+ Y +     + R    S    G IT
Sbjct: 859  QSAHYSVSVNEDRPMGSTIVVISASDDDVGENARITYLLEDNLPQFRIDADS----GAIT 914

Query: 425  VAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
            +  PLD++ +  Y L ++A D+G   ++DT  V++ + D N+ AP F  + YT  V EDA
Sbjct: 915  LQAPLDYEDQVTYTLAITARDNGIPQKADTTYVEVMVNDVNDNAPQFVASHYTGLVSEDA 974

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
            P  T+VL +SATD D   N ++ Y+  +          D  F I P +G + T + LDRE
Sbjct: 975  PPFTSVLQISATDRDAHANGRVQYTFQNGEDG------DGDFTIEPTSGIVRTVRRLDRE 1028

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
             +S Y LT  A D GVP L     +++ V DVNDN PVF  + +   + E+++VG+ V+Q
Sbjct: 1029 AVSVYELTAYAVDRGVPPLRTPVSIQVMVQDVNDNAPVFPAEEFEVRVKENSIVGSVVAQ 1088

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
            + A D D G N  I Y++   +  E  F +D  SG +     LD E+   +    + +  
Sbjct: 1089 ITAVDPDEGPNAHIMYQIVEGNIPE-LFQMDIFSGELTALIDLDYEARQEY---VIVVQA 1144

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVFESDCLTF--YISENS---PIGTTIGEIRAHDPDEG 717
             + P  S   VH+++ D ND+ PV  +  + F  Y+S  S   P G  IG I A+DPD  
Sbjct: 1145 TSAPLVSRATVHVRLVDQNDNSPVLNNFQILFNNYVSNRSDTFPSG-IIGRIPAYDPDVS 1203

Query: 718  PNAVVHYSIKGGDD 731
             +  + YS + G++
Sbjct: 1204 DH--LFYSFERGNE 1215



 Score =  271 bits (665), Expect = 2e-70
 Identities = 202/648 (31%), Positives = 310/648 (47%), Gaps = 28/648 (4%)

Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295
           +R  T+      R   +  P+F    +Q  V EN   G +++RV A D D G    L Y+
Sbjct: 304 ARKVTSANRARFRRAANRHPQFPQYNYQTLVPENEAAGTAVLRVVAQDPDAGEAGRLVYS 363

Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355
           +     + +++L  +IDP+SG + T+  LDRE+  ++ L VTA D G P  SAT      
Sbjct: 364 LAALMNSRSLEL-FSIDPQSGLIRTAAALDRESMERHYLRVTAQDHGSPRLSATTMVAVT 422

Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITG---GNTRG 410
                     F   QY   L E+   G P++ L ATD D   +  L Y   G        
Sbjct: 423 VADRNDHSPVFEQAQYRETLRENVEEGYPILQLRATDGDAPPNANLRYRFVGPPAARAAA 482

Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS----GGRSDTAMVQINITDANNYA 466
             +       GLI+ +  +D +    Y L V A+D     G RS T  V I + D N+ A
Sbjct: 483 AAAFEIDPRSGLISTSGRVDREHMESYELVVEASDQGQEPGPRSATVRVHITVLDENDNA 542

Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
           P F    Y A V ED    T VL V+ATD D   N  + Y++   IS  +  H    F I
Sbjct: 543 PQFSEKRYVAQVREDVRPHTVVLRVTATDRDKDANGLVHYNI---ISGNSRGH----FAI 595

Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV-EISVVDVNDNEPVFKQQL 585
           +  TG I     LD E    Y L + A+D G P LS+ T +  I VVD+ND+ P+F    
Sbjct: 596 DSLTGEIQVVAPLDFEAEREYALRIRAQDAGRPPLSNNTGLASIQVVDINDHIPIFVSTP 655

Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645
           +  +++E+A +G SV  + A DAD G N R+ Y L      +  FVI+ A+G +  +  L
Sbjct: 656 FQVSVLENAPLGHSVIHIQAVDADHGENARLEYSLTGV-APDTPFVINSATGWVSVSGPL 714

Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
           DRESV  +     A D G+PP S++  V + + D+ND+ P F        ++E++ +GT+
Sbjct: 715 DRESVEHYFFGVEARDHGSPPLSASASVTVTVLDVNDNRPEFTMKEYHLRLNEDAAVGTS 774

Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM-VDLDYESPRKKYE 764
           +  + A D D   N+ + Y I GG+  N F++ T+ G     LVT+ + LDY+  R  ++
Sbjct: 775 VVSVTAVDRD--ANSAISYQITGGNTRNRFAISTQGG---VGLVTLALPLDYKQER-YFK 828

Query: 765 LVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADV 823
           LV+ A+   L +   V I +TD N + PV +      +  +D  P+G     + A D DV
Sbjct: 829 LVLTASDRALHDHCYVHINITDANTHRPVFQSAHYSVSVNED-RPMGSTIVVISASDDDV 887

Query: 824 TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            +  +   L  +N     ++  +G++TL   L+       T+ ++  D
Sbjct: 888 GENARITYLLEDNLPQFRIDADSGAITLQAPLDYEDQVTYTLAITARD 935



 Score = 79.8 bits (188), Expect = 1e-12
 Identities = 62/225 (27%), Positives = 102/225 (45%), Gaps = 29/225 (12%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            Q+ V D ND++PVF  +++E  V+E +  G+ V  + A D D G NA + Y I       
Sbjct: 1054 QVMVQDVNDNAPVFPAEEFEVRVKENSIVGSVVAQITAVDPDEGPNAHIMYQI------- 1106

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                            + ++F++D  SG L     LD E    Y ++V+AT      S  
Sbjct: 1107 ------------VEGNIPELFQMDIFSGELTALIDLDYEARQEYVIVVQAT------SAP 1148

Query: 130  LSSTATIHVNIIDDNDNYPQFS--EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
            L S AT+HV ++D NDN P  +  +  +   V        + +I +I A D DV  +  +
Sbjct: 1149 LVSRATVHVRLVDQNDNSPVLNNFQILFNNYVSNRSDTFPSGIIGRIPAYDPDV--SDHL 1206

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232
             Y+   GN      ++  SG++ L + LD  +     +++   DG
Sbjct: 1207 FYSFERGNELQLLVVNQTSGELRLSRKLDNNRPLVASMLVTVTDG 1251



 Score = 37.9 bits (84), Expect = 4.0
 Identities = 15/39 (38%), Positives = 19/39 (48%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  +   C S PC NG  C+     Y C C+   TG+DC
Sbjct: 1432 CETELDLCYSNPCRNGGACARREGGYTCVCRPRFTGEDC 1470



 Score = 37.9 bits (84), Expect = 4.0
 Identities = 23/83 (27%), Positives = 44/83 (53%), Gaps = 1/83 (1%)

Query: 2238 CTCNHLSTFAVLVDEVDVEFIPEPSLLESVTSYTAFSISLPLLLTSWAALCLIRGGAATV 2297
            C C+   TF VL+D    E +     L +V ++   ++S+  L+ + A L  +R   + V
Sbjct: 2512 CRCSRTGTFGVLMDASPRERLEGDLELLAVFTHVVVAVSVAALVLTAAILLSLRSLKSNV 2571

Query: 2298 SNSIHKHLIFSVFMAELLYLIAL 2320
               IH ++  ++ +AELL+L+ +
Sbjct: 2572 -RGIHANVAAALGVAELLFLLGI 2593


>UniRef50_Q9HCU4 Cluster: Cadherin EGF LAG seven-pass G-type receptor
            2 precursor; n=38; Euteleostomi|Rep: Cadherin EGF LAG
            seven-pass G-type receptor 2 precursor - Homo sapiens
            (Human)
          Length = 2923

 Score =  901 bits (2230), Expect = 0.0
 Identities = 492/1105 (44%), Positives = 668/1105 (60%), Gaps = 58/1105 (5%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D NDH PVFE Q+Y+ S+RE    G  VLT++ATD D   NA + Y   L+     
Sbjct: 277  ILVTDTNDHDPVFEQQEYKESLRENLEVGYEVLTVRATDGDAPPNANILY--RLLEGSGG 334

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +P +              VF ID RSG + TR  +DRE+V  Y + V+A+DQ      R 
Sbjct: 335  SPSE--------------VFEIDPRSGVIRTRGPVDREEVESYQLTVEASDQGRDPGPR- 379

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S+TA + +++ DDNDN PQFSEK Y V V ED  VT    + ++ A+D D G+N+ + Y+
Sbjct: 380  STTAAVFLSVEDDNDNAPQFSEKRYVVQVRED--VTPGAPVLRVTASDRDKGSNAVVHYS 437

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIRD 249
            I+ GN + QF +D+ +G + +V  LDYE  + Y L +RAQDGG P  SN + L+ + + D
Sbjct: 438  IMSGNARGQFYLDAQTGALDVVSPLDYETTKEYTLRVRAQDGGRPPLSNVSGLVTVQVLD 497

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            +NDNAP F ++ FQ +V E+VP+GY ++ VQA DAD G NA L Y +    +    D P 
Sbjct: 498  INDNAPIFVSTPFQATVLESVPLGYLVLHVQAIDADAGDNARLEYRLAGVGH----DFPF 553

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            TI+  +GW+  + +LDRE    Y   V A D G P  +A+A+              F   
Sbjct: 554  TINNGTGWISVAAELDREEVDFYSFGVEARDHGTPALTASASVSVTVLDVNDNNPTFTQP 613

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
            +Y V L ED   GT VVT++A D D  + + Y+IT GNTR RFSITSQ+G GL+++A PL
Sbjct: 614  EYTVRLNEDAAVGTSVVTVSAVDRDAHSVITYQITSGNTRNRFSITSQSGGGLVSLALPL 673

Query: 430  DFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
            D+K ER+YVL V+A+D G R DTA + +N+TDAN + PVF+++ YT +V ED P GTTV+
Sbjct: 674  DYKLERQYVLAVTASD-GTRQDTAQIVVNVTDANTHRPVFQSSHYTVNVNEDRPAGTTVV 732

Query: 490  VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
            ++SATD D G NA+ITY +   I          QF I+  TGA+TT   LD E    Y L
Sbjct: 733  LISATDEDTGENARITYFMEDSIP---------QFRIDADTGAVTTQAELDYEDQVSYTL 783

Query: 550  TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
             +TARD G+P  SDTT +EI V DVNDN P F +  Y  ++ ED    TSV Q+ ATD D
Sbjct: 784  AITARDNGIPQKSDTTYLEILVNDVNDNAPQFLRDSYQGSVYEDVPPFTSVLQISATDRD 843

Query: 610  VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669
             GLNGR+ Y     D  +G F+++  SG++RT + LDRE+VA + L+A A+D G PP  +
Sbjct: 844  SGLNGRVFYTFQGGDDGDGDFIVESTSGIVRTLRRLDRENVAQYVLRAYAVDKGMPPART 903

Query: 670  TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729
             + V + + D+ND+PPVFE D    ++ ENSPIG  +  + A DPDEG NA + Y I  G
Sbjct: 904  PMEVTVTVLDVNDNPPVFEQDEFDVFVEENSPIGLAVARVTATDPDEGTNAQIMYQIVEG 963

Query: 730  DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVND 789
            +    F L+   G    EL  +VDLDYE  R +Y LVI+A S PL +   V + + D ND
Sbjct: 964  NIPEVFQLDIFSG----ELTALVDLDYED-RPEYVLVIQATSAPLVSRATVHVRLLDRND 1018

Query: 790  NAPVMKDFQIIFNNY----KDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNET 845
            N PV+ +F+I+FNNY       FP G  GRVPA+D D++D L Y    GN  +L+LLN +
Sbjct: 1019 NPPVLGNFEILFNNYVTNRSSSFPGGAIGRVPAHDPDISDSLTYSFERGNELSLVLLNAS 1078

Query: 846  TGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTA 905
            TG + LS  L+ N P  A M V V+DGV+ + A   L V +IT+EML +SIT+RL DM+ 
Sbjct: 1079 TGELKLSRALDNNRPLEAIMSVLVSDGVHSVTAQCALRVTIITDEMLTHSITLRLEDMSP 1138

Query: 906  EQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVT-GNILNVSFSARRPDAEVGVAG 964
            E+FLSPLLG FI  +AA +  P +++ +F+VQ DTD   G+ILNVS S  +P    G  G
Sbjct: 1139 ERFLSPLLGLFIQAVAATLATPPDHVVVFNVQRDTDAPGGHILNVSLSVGQPP---GPGG 1195

Query: 965  DPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASG 1024
             P P      L+ER+YL+R+ L  ++  +VLPFDDNIC+ EPC N+  C++VL+F +++ 
Sbjct: 1196 GP-PFLPSEDLQERLYLNRSLLTAISAQRVLPFDDNICLREPCENYMRCVSVLRFDSSAP 1254

Query: 1025 FVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARRE 1084
            F+ S SVLFRPI+PV    C+CP GFTG  CET +        G    CRS       RE
Sbjct: 1255 FIASSSVLFRPIHPVGGLRCRCPPGFTGDYCETEVDLCYSRPCGPHGRCRS-------RE 1307

Query: 1085 GGILCQGCSIDAAYTTAVCELRARS 1109
            GG  C  C     YT   CE+ ARS
Sbjct: 1308 GGYTCL-CR--DGYTGEHCEVSARS 1329



 Score =  626 bits (1547), Expect = e-177
 Identities = 337/941 (35%), Positives = 499/941 (53%), Gaps = 82/941 (8%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            +TC C +G+TG +CE       C       +C++G  CV    GG  C   S D  +   
Sbjct: 1310 YTCLCRDGYTGEHCEVSARSGRCTP----GVCKNGGTCVNLLVGGFKCDCPSGD--FEKP 1363

Query: 1102 VCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVS 1161
             C++  RSFP  SF+TF GL++R    L L FAT+   GLLLYNGR+NE+HDF+ALE++ 
Sbjct: 1364 YCQVTTRSFPAHSFITFRGLRQRFHFTLALSFATKERDGLLLYNGRFNEKHDFVALEVIQ 1423

Query: 1162 SEAGRGGGPGLRFSFSLGGGKSEIT--VEGNVGDGSWHTVEIEYFNRTI----------- 1208
             +        ++ +FS G   + ++  V G V DG WHTV+++Y+N+ +           
Sbjct: 1424 EQ--------VQLTFSAGESTTTVSPFVPGGVSDGQWHTVQLKYYNKPLLGQTGLPQGPS 1475

Query: 1209 -----TMILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQ 1263
                  + +D CD  ++L   +  G  Y+CA           +       + LDLTGPL 
Sbjct: 1476 EQKVAVVTVDGCDTGVALRFGSVLG-NYSCA----------AQGTQGGSKKSLDLTGPLL 1524

Query: 1264 IGGLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCY 1323
            +GG+P++P SF V+ + FVGC+ +  +D + ID+  ++A+NGT+ GCP K++ C S  C+
Sbjct: 1525 LGGVPDLPESFPVRMRQFVGCMRNLQVDSRHIDMADFIANNGTVPGCPAKKNVCDSNTCH 1584

Query: 1324 NGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLRPIQLPWLNALSI 1383
            NG  C + WD + C+C  G  GK CA     P  F G  +++++ L  PI  PW  +L  
Sbjct: 1585 NGGTCVNQWDAFSCECPLGFGGKSCAQEMANPQHFLGSSLVAWHGLSLPISQPWYLSLMF 1644

Query: 1384 RTRQRDAFVM----------SIQLKSGLLHYSYNG-----ETMYLPMATLSDGAWHRIEI 1428
            RTRQ D  ++          ++QL+ G +  S  G      ++ L     +DG WH  ++
Sbjct: 1645 RTRQADGVLLQAITRGRSTITLQLREGHVMLSVEGTGLQASSLRLEPGRANDGDWHHAQL 1704

Query: 1429 KWLGTD-----ISVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGLLASDVGFFE 1483
              LG         ++ DYG +      L  ++ G ++  I +GG+   AG +A     F 
Sbjct: 1705 A-LGASGGPGHAILSFDYGQQRA-EGNLGPRLHGLHLSNITVGGIPGPAGGVARG---FR 1759

Query: 1484 GCIQDVRIGTAQSLLNR--PTVRE--NVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTC 1539
            GC+Q VR+      +N   P+  E  NV  GC     C  + CP  S C   WDS +C+C
Sbjct: 1760 GCLQGVRVSDTPEGVNSLDPSHGESINVEQGCSLPDPCDSNPCPANSYCSNDWDSYSCSC 1819

Query: 1540 EAGRVGPQCVSACELGPCG-AARCV-PDQTPKGYSCACEPGYTLTTSGCIESGKEECPGG 1597
            + G  G  C + C+L PC   + C      P GY+C C P Y      C     + CP G
Sbjct: 1820 DPGYYGDNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYL--GPYCETRIDQPCPRG 1877

Query: 1598 WWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCE 1657
            WWG   CGPC CDV++G+ P CNK +G+CHCKENHY+P G+  CL C CY  GS +  C+
Sbjct: 1878 WWGHPTCGPCNCDVSKGFDPDCNKTSGECHCKENHYRPPGSPTCLLCDCYPTGSLSRVCD 1937

Query: 1658 AATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETI 1717
               GQC C+PGVIGR CD C N +AEVT N GCEV YD CPR+   G+WWPRT+FG+   
Sbjct: 1938 PEDGQCPCKPGVIGRQCDRCDNPFAEVTTN-GCEVNYDSCPRAIEAGIWWPRTRFGLPAA 1996

Query: 1718 TDCPPGSSGRATRTCDETKDVPWQDPDMFNCTTATFYQLRKQLHKIETGELTMNTFVGVR 1777
              CP GS G A R CDE +   W  P++FNCT+ TF +L+    +++  E  +++    +
Sbjct: 1997 APCPKGSFGTAVRHCDEHRG--WLPPNLFNCTSITFSELKGFAERLQRNESGLDSGRSQQ 2054

Query: 1778 VAADLSTACANTPRLYGADVVVAEGILLELMDYELRQAGLNLTHSQDKDYVRNLLKSTNT 1837
            +A  L  A  +T   +G+DV VA  +   L+ +E  Q G  L+ +QD  +  NLL+  + 
Sbjct: 2055 LALLLRNATQHTAGYFGSDVKVAYQLATRLLAHESTQRGFGLSATQDVHFTENLLRVGSA 2114

Query: 1838 ILNVEYEREWKRIRELTGHGAELLVQKFDEYIAVLAESQHDTYTSPFEIVTKDVVISVDT 1897
            +L+   +R W+ I++  G G   L+Q ++ Y + LA++   TY SPF IVT ++VISV  
Sbjct: 2115 LLDTANKRHWELIQQTEG-GTAWLLQHYEAYASALAQNMRHTYLSPFTIVTPNIVISVVR 2173

Query: 1898 VTSESIYGFEPTQLNRLNVDS-YTTERVVALPDTSAFIHSP 1937
            +   +  G +  +   L  +     E  V LP+ S F  +P
Sbjct: 2174 LDKGNFAGAKLPRYEALRGEQPPDLETTVILPE-SVFRETP 2213



 Score =  363 bits (892), Expect = 5e-98
 Identities = 253/759 (33%), Positives = 374/759 (49%), Gaps = 44/759 (5%)

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY---AIIGGNTQMQFSIDS 204
           PQF   +Y  +V E+      PV A ++A D D G    + Y   A+    +   FS+D 
Sbjct: 179 PQFQPPSYQATVPEN-QPAGTPV-ASLRAIDPDEGEAGRLEYTMDALFDSRSNQFFSLDP 236

Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
           ++G V+  + LD E   ++   + AQD G P RS    L I + D ND+ P F    ++E
Sbjct: 237 VTGAVTTAEELDRETKSTHVFRVTAQDHGMPRRSALATLTILVTDTNDHDPVFEQQEYKE 296

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
           S+ EN+ +GY ++ V+A D D   NA + Y + +    G+      IDPRSG + T G +
Sbjct: 297 SLRENLEVGYEVLTVRATDGDAPPNANILYRLLEGS-GGSPSEVFEIDPRSGVIRTRGPV 355

Query: 325 DRETQAKYQLLVTATD-GGDP-PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382
           DRE    YQL V A+D G DP PRS TA               F   +Y V++ ED  PG
Sbjct: 356 DREEVESYQLTVEASDQGRDPGPRSTTAAVFLSVEDDNDNAPQFSEKRYVVQVREDVTPG 415

Query: 383 TPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440
            PV+ +TA+D D+ +   +HY I  GN RG+F + +Q   G + V  PLD++  + Y L 
Sbjct: 416 APVLRVTASDRDKGSNAVVHYSIMSGNARGQFYLDAQT--GALDVVSPLDYETTKEYTLR 473

Query: 441 VSATDSGGR----SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496
           V A D GGR    + + +V + + D N+ AP+F + P+ A+V E  P+G  VL V A D+
Sbjct: 474 VRAQD-GGRPPLSNVSGLVTVQVLDINDNAPIFVSTPFQATVLESVPLGYLVLHVQAIDA 532

Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556
           D G NA++ Y L       A   HD  F IN  TG I+    LDRE +  Y   V ARD 
Sbjct: 533 DAGDNARLEYRL-------AGVGHDFPFTINNGTGWISVAAELDREEVDFYSFGVEARDH 585

Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616
           G P+L+ +  V ++V+DVNDN P F Q  YT  + EDA VGTSV  V A D D   +  I
Sbjct: 586 GTPALTASASVSVTVLDVNDNNPTFTQPEYTVRLNEDAAVGTSVVTVSAVDRDA--HSVI 643

Query: 617 HYEL-DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675
            Y++     R   S       G++     LD +    + L   A DG    +  T  + +
Sbjct: 644 TYQITSGNTRNRFSITSQSGGGLVSLALPLDYKLERQYVLAVTASDG---TRQDTAQIVV 700

Query: 676 KIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735
            + D N   PVF+S   T  ++E+ P GTT+  I A D D G NA + Y ++  D    F
Sbjct: 701 NVTDANTHRPVFQSSHYTVNVNEDRPAGTTVVLISATDEDTGENARITYFME--DSIPQF 758

Query: 736 SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAP 792
            ++    +D   + T  +LDYE  +  Y L I A     P   +   +EILV DVNDNAP
Sbjct: 759 RID----ADTGAVTTQAELDYED-QVSYTLAITARDNGIPQKSDTTYLEILVNDVNDNAP 813

Query: 793 VMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSM- 849
                    + Y+D  P     ++ A D D  +  ++ Y    G++ +   + E+T  + 
Sbjct: 814 QFLRDSYQGSVYEDVPPFTSVLQISATDRDSGLNGRVFYTFQGGDDGDGDFIVESTSGIV 873

Query: 850 -TLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887
            TL      NV +      +V  G+   +  M+++V ++
Sbjct: 874 RTLRRLDRENVAQYVLRAYAVDKGMPPARTPMEVTVTVL 912



 Score =  361 bits (888), Expect = 2e-97
 Identities = 273/851 (32%), Positives = 414/851 (48%), Gaps = 69/851 (8%)

Query: 20  SPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXX 79
           +P F+   Y+A+V E   +GT V +L+A D D G+   +EYT++ +     N        
Sbjct: 178 APQFQPPSYQATVPENQPAGTPVASLRAIDPDEGEAGRLEYTMDALFDSRSN-------- 229

Query: 80  XXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVN 139
                     F +D  +GA+ T   LDRE  + +   V A D   P   R S+ AT+ + 
Sbjct: 230 --------QFFSLDPVTGAVTTAEELDRETKSTHVFRVTAQDHGMP---RRSALATLTIL 278

Query: 140 IIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII---GGNT 196
           + D ND+ P F ++ Y  S+ E++ V     +  ++ATD D   N+ I Y ++   GG+ 
Sbjct: 279 VTDTNDHDPVFEQQEYKESLRENLEV--GYEVLTVRATDGDAPPNANILYRLLEGSGGSP 336

Query: 197 QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD-GGSPS-RSNTTQLLINIRDVNDNA 254
              F ID  SG +     +D E+V SY+L + A D G  P  RS T  + +++ D NDNA
Sbjct: 337 SEVFEIDPRSGVIRTRGPVDREEVESYQLTVEASDQGRDPGPRSTTAAVFLSVEDDNDNA 396

Query: 255 PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR 314
           P+F    +   V E+V  G  ++RV A D D+G NA + Y++     +GN      +D +
Sbjct: 397 PQFSEKRYVVQVREDVTPGAPVLRVTASDRDKGSNAVVHYSI----MSGNARGQFYLDAQ 452

Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRS-ATATXXXXXXXXXXXXXXFMPGQYEV 373
           +G +     LD ET  +Y L V A DGG PP S  +                F+   ++ 
Sbjct: 453 TGALDVVSPLDYETTKEYTLRVRAQDGGRPPLSNVSGLVTVQVLDINDNAPIFVSTPFQA 512

Query: 374 ELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431
            + E  P G  V+ + A DAD  DN RL Y + G      F  T  NG G I+VA  LD 
Sbjct: 513 TVLESVPLGYLVLHVQAIDADAGDNARLEYRLAG--VGHDFPFTINNGTGWISVAAELDR 570

Query: 432 KQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVL 489
           ++   Y   V A D G  + TA   +++T  D N+  P F    YT  + EDA +GT+V+
Sbjct: 571 EEVDFYSFGVEARDHGTPALTASASVSVTVLDVNDNNPTFTQPEYTVRLNEDAAVGTSVV 630

Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA--ITTNKLLDRETMSGY 547
            VSA D D   ++ ITY ++S        +   +F I  Q+G   ++    LD +    Y
Sbjct: 631 TVSAVDRDA--HSVITYQITS-------GNTRNRFSITSQSGGGLVSLALPLDYKLERQY 681

Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
           +L VTA DG   +  DT  + ++V D N + PVF+   YT N+ ED   GT+V  + ATD
Sbjct: 682 VLAVTASDG---TRQDTAQIVVNVTDANTHRPVFQSSHYTVNVNEDRPAGTTVVLISATD 738

Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
            D G N RI Y ++    +   F ID  +G + T   LD E   ++ L   A D G P +
Sbjct: 739 EDTGENARITYFMEDSIPQ---FRIDADTGAVTTQAELDYEDQVSYTLAITARDNGIPQK 795

Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
           S T  + I + D+ND+ P F  D     + E+ P  T++ +I A D D G N  V Y+ +
Sbjct: 796 SDTTYLEILVNDVNDNAPQFLRDSYQGSVYEDVPPFTSVLQISATDRDSGLNGRVFYTFQ 855

Query: 728 GGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKKYEL---VIRAASPPLWNDVRVEIL 783
           GGDD +  F +E+  G  +    T+  LD E+   +Y L    +    PP    + V + 
Sbjct: 856 GGDDGDGDFIVESTSGIVR----TLRRLDRENV-AQYVLRAYAVDKGMPPARTPMEVTVT 910

Query: 784 VTDVNDNAPVMKDFQI-IFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILSGNNANL 839
           V DVNDN PV +  +  +F   ++  P+G    RV A D D     ++ Y+I+ GN   +
Sbjct: 911 VLDVNDNPPVFEQDEFDVF--VEENSPIGLAVARVTATDPDEGTNAQIMYQIVEGNIPEV 968

Query: 840 ILLNETTGSMT 850
             L+  +G +T
Sbjct: 969 FQLDIFSGELT 979



 Score =  281 bits (688), Expect = 3e-73
 Identities = 203/635 (31%), Positives = 311/635 (48%), Gaps = 29/635 (4%)

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
           R+VN  AP+F    +Q +V EN P G  +  ++A D DEG    L YTM D  +    + 
Sbjct: 173 RNVN-TAPQFQPPSYQATVPENQPAGTPVASLRAIDPDEGEAGRLEYTM-DALFDSRSNQ 230

Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
             ++DP +G V T+ +LDRET++ +   VTA D G P RSA AT              F 
Sbjct: 231 FFSLDPVTGAVTTAEELDRETKSTHVFRVTAQDHGMPRRSALATLTILVTDTNDHDPVFE 290

Query: 368 PGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLH--YEITGGNTRGRFSITSQNGRGL 422
             +Y+  L E+   G  V+T+ ATD D     N L+   E +GG+    F I  ++  G+
Sbjct: 291 QQEYKESLRENLEVGYEVLTVRATDGDAPPNANILYRLLEGSGGSPSEVFEIDPRS--GV 348

Query: 423 ITVAQPLDFKQERRYVLTVSATDS----GGRSDTAMVQINITDANNYAPVFENAPYTASV 478
           I    P+D ++   Y LTV A+D     G RS TA V +++ D N+ AP F    Y   V
Sbjct: 349 IRTRGPVDREEVESYQLTVEASDQGRDPGPRSTTAAVFLSVEDDNDNAPQFSEKRYVVQV 408

Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
            ED   G  VL V+A+D D G NA + YS+ S        +   QF ++ QTGA+     
Sbjct: 409 REDVTPGAPVLRVTASDRDKGSNAVVHYSIMS-------GNARGQFYLDAQTGALDVVSP 461

Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTD-VEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
           LD ET   Y L V A+DGG P LS+ +  V + V+D+NDN P+F    + A ++E   +G
Sbjct: 462 LDYETTKEYTLRVRAQDGGRPPLSNVSGLVTVQVLDINDNAPIFVSTPFQATVLESVPLG 521

Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
             V  V A DAD G N R+ Y L      +  F I+  +G I     LDRE V  +    
Sbjct: 522 YLVLHVQAIDADAGDNARLEYRLAGVG-HDFPFTINNGTGWISVAAELDREEVDFYSFGV 580

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
            A D GTP  +++  V + + D+ND+ P F     T  ++E++ +GT++  + A D D  
Sbjct: 581 EARDHGTPALTASASVSVTVLDVNDNNPTFTQPEYTVRLNEDAAVGTSVVTVSAVDRD-- 638

Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND 777
            ++V+ Y I  G+  N FS+ ++ G     L   + LDY+  R +Y L + A+     + 
Sbjct: 639 AHSVITYQITSGNTRNRFSITSQSGGGLVSLA--LPLDYKLER-QYVLAVTASDGTRQDT 695

Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNN 836
            ++ + VTD N + PV +      N  +D  P G     + A D D  +  +      ++
Sbjct: 696 AQIVVNVTDANTHRPVFQSSHYTVNVNED-RPAGTTVVLISATDEDTGENARITYFMEDS 754

Query: 837 ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
                ++  TG++T   +L+       T+ ++  D
Sbjct: 755 IPQFRIDADTGAVTTQAELDYEDQVSYTLAITARD 789



 Score =  214 bits (523), Expect = 3e-53
 Identities = 155/438 (35%), Positives = 223/438 (50%), Gaps = 26/438 (5%)

Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523
           N AP F+   Y A+V E+ P GT V  + A D D G   ++ Y++ +   + +    +Q 
Sbjct: 176 NTAPQFQPPSYQATVPENQPAGTPVASLRAIDPDEGEAGRLEYTMDALFDSRS----NQF 231

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583
           F ++P TGA+TT + LDRET S ++  VTA+D G+P  S    + I V D ND++PVF+Q
Sbjct: 232 FSLDPVTGAVTTAEELDRETKSTHVFRVTAQDHGMPRRSALATLTILVTDTNDHDPVFEQ 291

Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS--FVIDPASGVIRT 641
           Q Y  ++ E+  VG  V  V ATD D   N  I Y L        S  F IDP SGVIRT
Sbjct: 292 QEYKESLRENLEVGYEVLTVRATDGDAPPNANILYRLLEGSGGSPSEVFEIDPRSGVIRT 351

Query: 642 NKALDRESVATHDLKAVAIDGGTP--PQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699
              +DRE V ++ L   A D G    P+S+T  V + +ED ND+ P F        + E+
Sbjct: 352 RGPVDREEVESYQLTVEASDQGRDPGPRSTTAAVFLSVEDDNDNAPQFSEKRYVVQVRED 411

Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759
              G  +  + A D D+G NAVVHYSI  G+    F L+ + G+    L  +  LDYE+ 
Sbjct: 412 VTPGAPVLRVTASDRDKGSNAVVHYSIMSGNARGQFYLDAQTGA----LDVVSPLDYET- 466

Query: 760 RKKYELVIRA---ASPPLWN-DVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFPVGPF 813
            K+Y L +RA     PPL N    V + V D+NDNAP  V   FQ       +  P+G  
Sbjct: 467 TKEYTLRVRAQDGGRPPLSNVSGLVTVQVLDINDNAPIFVSTPFQA---TVLESVPLGYL 523

Query: 814 G-RVPAYDADVTD--KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVT 870
              V A DAD  D  +L+YR+    +     +N  TG ++++ +L+       +  V   
Sbjct: 524 VLHVQAIDADAGDNARLEYRLAGVGHDFPFTINNGTGWISVAAELDREEVDFYSFGVEAR 583

Query: 871 D-GVNEIKAMMQLSVRLI 887
           D G   + A   +SV ++
Sbjct: 584 DHGTPALTASASVSVTVL 601



 Score =  125 bits (301), Expect = 2e-26
 Identities = 104/337 (30%), Positives = 159/337 (47%), Gaps = 38/337 (11%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I V D ND++P F    Y+ SV E     T+VL + ATD+D G N  V YT +      
Sbjct: 802  EILVNDVNDNAPQFLRDSYQGSVYEDVPPFTSVLQISATDRDSGLNGRVFYTFQ------ 855

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
               +D               F ++  SG + T   LDRE VA+Y +   A D+  P +  
Sbjct: 856  -GGDDGDGD-----------FIVESTSGIVRTLRRLDRENVAQYVLRAYAVDKGMPPA-- 901

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
              +   + V ++D NDN P F +  + V V+E+  +     +A++ ATD D G N+ I Y
Sbjct: 902  -RTPMEVTVTVLDVNDNPPVFEQDEFDVFVEENSPI--GLAVARVTATDPDEGTNAQIMY 958

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             I+ GN    F +D  SG+++ +  LDYE    Y LVI+A      SR+    + + + D
Sbjct: 959  QIVEGNIPEVFQLDIFSGELTALVDLDYEDRPEYVLVIQATSAPLVSRAT---VHVRLLD 1015

Query: 250  VNDNAPRF--YTSLFQESV---SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
             NDN P    +  LF   V   S + P G +I RV A+D D  ++  LTY+       GN
Sbjct: 1016 RNDNPPVLGNFEILFNNYVTNRSSSFP-GGAIGRVPAHDPD--ISDSLTYSFE----RGN 1068

Query: 305  VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341
                + ++  +G +  S  LD     +  + V  +DG
Sbjct: 1069 ELSLVLLNASTGELKLSRALDNNRPLEAIMSVLVSDG 1105



 Score = 54.8 bits (126), Expect = 3e-05
 Identities = 45/148 (30%), Positives = 79/148 (53%), Gaps = 18/148 (12%)

Query: 2176 LKKPIRLQIWLDINRETFGSRTNPQCVHWS---TLRGSGEWSRVGCHTEIDYDWSPYSEE 2232
            L KP+ +Q  L    E    RT P CV W+    + G+G WS  GC  E+ +    +   
Sbjct: 2298 LDKPVTVQFRLLETEE----RTKPICVFWNHSILVSGTGGWSARGC--EVVFRNESH--- 2348

Query: 2233 PLLINCTCNHLSTFAVLVDEVDVEFIPEPSLLESVTSYTAFSISLPLLLTSWAALCLIRG 2292
               ++C CNH+++FAVL+D V      E   L+++T Y A  ++L  LL ++  L L+R 
Sbjct: 2349 ---VSCQCNHMTSFAVLMD-VSRRENGEILPLKTLT-YVALGVTLAALLLTFFFLTLLR- 2402

Query: 2293 GAATVSNSIHKHLIFSVFMAELLYLIAL 2320
               +  + I ++L  ++ +A+L++L+ +
Sbjct: 2403 ILRSNQHGIRRNLTAALGLAQLVFLLGI 2430



 Score = 37.5 bits (83), Expect = 5.3
 Identities = 23/76 (30%), Positives = 30/76 (39%), Gaps = 6/76 (7%)

Query: 1509 DGCQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC-VSA----CELGPCGAARC 1562
            D C++  D C    C P+ +C +     TC C  G  G  C VSA    C  G C     
Sbjct: 1283 DYCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEVSARSGRCTPGVCKNGGT 1342

Query: 1563 VPDQTPKGYSCACEPG 1578
              +    G+ C C  G
Sbjct: 1343 CVNLLVGGFKCDCPSG 1358


>UniRef50_Q4RXP0 Cluster: Chromosome 11 SCAF14979, whole genome
            shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
            Chromosome 11 SCAF14979, whole genome shotgun sequence -
            Tetraodon nigroviridis (Green puffer)
          Length = 2982

 Score =  810 bits (2004), Expect = 0.0
 Identities = 434/943 (46%), Positives = 593/943 (62%), Gaps = 45/943 (4%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D NDH+PVFE Q Y+ ++RE    G  VLT++ATD D   N  + Y I       +
Sbjct: 257  ITVSDTNDHNPVFEQQDYKENIRENLEIGYEVLTVRATDGDAPVNGNILYRI-------I 309

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N   +            DVF ID RSG + TR  +DRE+V  Y +LV+A DQ      R 
Sbjct: 310  NGNGS-----------NDVFEIDSRSGVIRTRGLVDREQVEAYMLLVEANDQGRDPGPR- 357

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S+TAT+H+ + DDNDN PQFSEK Y V V ED++   N  I ++ ATD D G+N+ + ++
Sbjct: 358  SATATVHIVVEDDNDNAPQFSEKRYVVQVPEDMA--PNTEILQVTATDEDRGSNAVVHFS 415

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIRD 249
            I+ GNT+ QF ID+ +G + LV  LDYE  + Y L IRAQDGG P  SN + L+ + + D
Sbjct: 416  IMSGNTRGQFYIDAQTGKMDLVSHLDYEANKEYTLRIRAQDGGRPPLSNISGLVTVQVLD 475

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            VNDNAP F ++ FQ +V ENVP+GYSI+ +QA DAD G N+ L Y +T    T N   P 
Sbjct: 476  VNDNAPIFVSTPFQATVLENVPLGYSIIHIQAVDADSGDNSRLEYRLTST--TPN--FPF 531

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             I+  +GW+  + +LDRE+   Y   V A D G P  S++A+              F   
Sbjct: 532  AINNSTGWIVVAAELDRESVDFYNFGVEARDQGYPVMSSSASISMTVLDVNDNNPEFTQK 591

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
             Y + L ED   GT V+T++A D D ++ + Y+I+ GNTR RFSITSQ+G GLIT+A PL
Sbjct: 592  AYYMRLNEDAAVGTSVLTVSAVDQDINSVVTYQISSGNTRNRFSITSQSGGGLITLALPL 651

Query: 430  DFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
            D+K ER+YVLT++A+D G   DTA V +N+TDAN + PVF+++ YT ++ ED P+GTTV+
Sbjct: 652  DYKLERQYVLTITASD-GTLFDTAKVFVNVTDANTHRPVFQSSHYTVNINEDRPMGTTVV 710

Query: 490  VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
            ++SATD D G NA+ITY +   I          QF I+P +GA+TT   LD E    Y L
Sbjct: 711  LISATDEDTGENARITYFMDDSIP---------QFDIDPDSGAVTTQMELDYEDQVSYTL 761

Query: 550  TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
             +TARD G+P  SDTT +EI V DVNDN P F +  Y  ++MED  V TSV QV ATD D
Sbjct: 762  AITARDNGIPQKSDTTYLEILVNDVNDNGPRFLRDHYVGSVMEDVPVFTSVVQVSATDRD 821

Query: 610  VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669
             GLNGR+ Y     +  +G F+I+  SG++RT + LDRE+V  ++L+A A+D G P   +
Sbjct: 822  SGLNGRVFYTFQGGEDGDGDFIIESTSGIVRTLRRLDRENVPVYNLQAFAVDKGVPALKT 881

Query: 670  TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729
             V +H+ I D+ND+PPVFE D L   + ENSPIG  +G + A DPDEG NA + Y I  G
Sbjct: 882  PVNIHVTILDVNDNPPVFEKDELDIMVEENSPIGLVVGHVSATDPDEGSNAQIMYQIVEG 941

Query: 730  DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVND 789
            +    F L+   G    EL +++DLDYE+ R +Y +V++A S PL +   V I + D ND
Sbjct: 942  NIPEVFQLDIFSG----ELTSLIDLDYET-RNEYVIVVQATSAPLVSRATVHIKLVDKND 996

Query: 790  NAPVMKDFQIIFNNY----KDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNET 845
            N PV+K+FQIIFNNY       FP G  GR+PA+D DV+D+L Y    GN  NL+LLN++
Sbjct: 997  NVPVLKNFQIIFNNYVTNKYSSFPSGVIGRIPAHDPDVSDQLHYSFEVGNELNLVLLNQS 1056

Query: 846  TGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTA 905
            TG + LS  L+ N P  A+M +SV+DGV+ + A   L V +IT+EML NSIT+RL + + 
Sbjct: 1057 TGEIQLSQALDNNRPLEASMRISVSDGVHAVSAQCLLQVTIITDEMLSNSITLRLANTSQ 1116

Query: 906  EQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILN 948
            EQFLS LL  F+DG+A ++   ++++ IF++QDDTDV+  ILN
Sbjct: 1117 EQFLSLLLAQFLDGVARVLSASRQDVVIFNIQDDTDVSARILN 1159



 Score =  395 bits (973), Expect = e-108
 Identities = 200/503 (39%), Positives = 273/503 (54%), Gaps = 39/503 (7%)

Query: 1256 LDLTGPLQIGGLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRS 1315
            LDLTGPL +GG+P +P  F V+N+ F+GCI +  +D++ +D+ S++A+NGTL GC  KR 
Sbjct: 1524 LDLTGPLLLGGVPKLPEDFPVRNRQFMGCIRNLRVDNQHVDMASFIANNGTLPGCSAKRH 1583

Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLRPIQ- 1374
             C++ PC NG  C +LW ++ CDC  G  GK C      P RF G+ +L +N +      
Sbjct: 1584 FCNTNPCLNGGTCVNLWGSFSCDCPLGFGGKSCERVMASPQRFLGNSLLQWNNMAAVASS 1643

Query: 1375 LPWLNALSIRTRQRDAFVMSI----------QLKSGL----LHYSYNGETMYLPMATLSD 1420
            +PW   L +RTRQ  A ++ I          QL+ G     LH   N     L    ++D
Sbjct: 1644 VPWHVELMLRTRQASAILLHISSGLQHNLTLQLRDGSVLMGLHQGENSTLSRLEEVLVND 1703

Query: 1421 GAWH--RIEIKWLGTDIS-----VTVDYGL--RTVLMPMLAN-----KIQGQYIGKILIG 1466
            G WH  +++I  LG  +S     +++D GL  R    P  A+     K++   +  + +G
Sbjct: 1704 GEWHHLQLDISSLGRPLSHHKAVLSLDQGLYLREAAAPFQASMEVDGKLRESKLKTVSVG 1763

Query: 1467 GLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRPTVRENVRDGCQSRADCMLSICPPYS 1526
            GL    G +      F GCIQ +RIG A SL     V  NV  GC     C  + CP  S
Sbjct: 1764 GLAAPGGKILQG---FRGCIQGLRIGGALSLSQARKV--NVEPGCSVPDPCSSNPCPANS 1818

Query: 1527 KCVTSWDSSTCTCEAGRVGPQCVSACELGPCG-AARCVPD-QTPKGYSCACEPGYTLTTS 1584
             C   WDS +CTC  G  G  C  AC L PC   + C     + +GY+C C   Y     
Sbjct: 1819 YCRDDWDSHSCTCLTGFYGNNCTDACSLNPCEHESVCTRRLSSSRGYTCDCSRNYF--GH 1876

Query: 1585 GCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPC 1644
             C +     CP G WG   CGPC C   +G+   CNK +G+C CK+NHY+PEG+  CL C
Sbjct: 1877 YCEKKTDLPCPRGQWGHKTCGPCNCQTDKGFDFDCNKTSGECRCKDNHYRPEGSGGCLLC 1936

Query: 1645 QCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGG 1704
             CY  GS + +C+  +GQC C+PGVIGR CD C N +AEV+ N GCEV+YD CP++   G
Sbjct: 1937 DCYPLGSFSRACDRDSGQCQCKPGVIGRQCDRCDNPFAEVSAN-GCEVIYDSCPQAIEAG 1995

Query: 1705 VWWPRTKFGVETITDCPPGSSGR 1727
            +WWPRTKFG+     CP G+ GR
Sbjct: 1996 IWWPRTKFGLPAAVSCPRGTLGR 2018



 Score =  353 bits (869), Expect = 3e-95
 Identities = 263/832 (31%), Positives = 395/832 (47%), Gaps = 59/832 (7%)

Query: 33  REGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRI 92
           R  +  G   L LKA D D G+   +EY IE +     N                 +F +
Sbjct: 171 RRTSQPGRPSLVLKAVDADEGEAGRLEYFIEALFDSRSN----------------SLFAV 214

Query: 93  DGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSE 152
           D  +GA+ T   LDRE    +   V A D  +P   R ++ AT+ + + D ND+ P F +
Sbjct: 215 DPANGAVSTVEVLDRETKDTHVFRVTAVDHGAP---RRTAMATLTITVSDTNDHNPVFEQ 271

Query: 153 KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN-TQMQFSIDSLSGDVSL 211
           + Y  ++ E++ +     +  ++ATD D   N  I Y II GN +   F IDS SG +  
Sbjct: 272 QDYKENIRENLEI--GYEVLTVRATDGDAPVNGNILYRIINGNGSNDVFEIDSRSGVIRT 329

Query: 212 VKTLDYEQVRSYRLVIRAQD-GGSPS-RSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269
              +D EQV +Y L++ A D G  P  RS T  + I + D NDNAP+F    +   V E+
Sbjct: 330 RGLVDREQVEAYMLLVEANDQGRDPGPRSATATVHIVVEDDNDNAPQFSEKRYVVQVPED 389

Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329
           +     I++V A D D G NA + +++     +GN      ID ++G +     LD E  
Sbjct: 390 MAPNTEILQVTATDEDRGSNAVVHFSI----MSGNTRGQFYIDAQTGKMDLVSHLDYEAN 445

Query: 330 AKYQLLVTATDGGDPPRS-ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388
            +Y L + A DGG PP S  +                F+   ++  + E+ P G  ++ +
Sbjct: 446 KEYTLRIRAQDGGRPPLSNISGLVTVQVLDVNDNAPIFVSTPFQATVLENVPLGYSIIHI 505

Query: 389 TATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446
            A DAD  +++RL Y +T  +T   F     N  G I VA  LD +    Y   V A D 
Sbjct: 506 QAVDADSGDNSRLEYRLT--STTPNFPFAINNSTGWIVVAAELDRESVDFYNFGVEARDQ 563

Query: 447 G--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504
           G    S +A + + + D N+  P F    Y   + EDA +GT+VL VSA D D  IN+ +
Sbjct: 564 GYPVMSSSASISMTVLDVNDNNPEFTQKAYYMRLNEDAAVGTSVLTVSAVDQD--INSVV 621

Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTGA--ITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
           TY +SS        +   +F I  Q+G   IT    LD +    Y+LT+TA DG   +L 
Sbjct: 622 TYQISS-------GNTRNRFSITSQSGGGLITLALPLDYKLERQYVLTITASDG---TLF 671

Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP 622
           DT  V ++V D N + PVF+   YT NI ED  +GT+V  + ATD D G N RI Y +D 
Sbjct: 672 DTAKVFVNVTDANTHRPVFQSSHYTVNINEDRPMGTTVVLISATDEDTGENARITYFMDD 731

Query: 623 KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND 682
              +   F IDP SG + T   LD E   ++ L   A D G P +S T  + I + D+ND
Sbjct: 732 SIPQ---FDIDPDSGAVTTQMELDYEDQVSYTLAITARDNGIPQKSDTTYLEILVNDVND 788

Query: 683 SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN-SFSLETRQ 741
           + P F  D     + E+ P+ T++ ++ A D D G N  V Y+ +GG+D +  F +E+  
Sbjct: 789 NGPRFLRDHYVGSVMEDVPVFTSVVQVSATDRDSGLNGRVFYTFQGGEDGDGDFIIESTS 848

Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801
           G      +  +D +           +    P L   V + + + DVNDN PV +  ++  
Sbjct: 849 GI--VRTLRRLDRENVPVYNLQAFAVDKGVPALKTPVNIHVTILDVNDNPPVFEKDELDI 906

Query: 802 NNYKDCFPVG-PFGRVPAYDADVTDKLQ--YRILSGNNANLILLNETTGSMT 850
              ++  P+G   G V A D D     Q  Y+I+ GN   +  L+  +G +T
Sbjct: 907 -MVEENSPIGLVVGHVSATDPDEGSNAQIMYQIVEGNIPEVFQLDIFSGELT 957



 Score =  343 bits (843), Expect = 4e-92
 Identities = 239/733 (32%), Positives = 361/733 (49%), Gaps = 44/733 (6%)

Query: 174 IKATDADVGANSAIRY---AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ 230
           +KA DAD G    + Y   A+    +   F++D  +G VS V+ LD E   ++   + A 
Sbjct: 183 LKAVDADEGEAGRLEYFIEALFDSRSNSLFAVDPANGAVSTVEVLDRETKDTHVFRVTAV 242

Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290
           D G+P R+    L I + D ND+ P F    ++E++ EN+ IGY ++ V+A D D  VN 
Sbjct: 243 DHGAPRRTAMATLTITVSDTNDHNPVFEQQDYKENIRENLEIGYEVLTVRATDGDAPVNG 302

Query: 291 ELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD-GGDP-PRSA 348
            + Y + + + + +V     ID RSG + T G +DRE    Y LLV A D G DP PRSA
Sbjct: 303 NILYRIINGNGSNDV---FEIDSRSGVIRTRGLVDREQVEAYMLLVEANDQGRDPGPRSA 359

Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGG 406
           TAT              F   +Y V++ ED  P T ++ +TATD D  +   +H+ I  G
Sbjct: 360 TATVHIVVEDDNDNAPQFSEKRYVVQVPEDMAPNTEILQVTATDEDRGSNAVVHFSIMSG 419

Query: 407 NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR----SDTAMVQINITDA 462
           NTRG+F I +Q G+  + +   LD++  + Y L + A D GGR    + + +V + + D 
Sbjct: 420 NTRGQFYIDAQTGK--MDLVSHLDYEANKEYTLRIRAQD-GGRPPLSNISGLVTVQVLDV 476

Query: 463 NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522
           N+ AP+F + P+ A+V E+ P+G +++ + A D+D G N+++ Y L+S   N        
Sbjct: 477 NDNAPIFVSTPFQATVLENVPLGYSIIHIQAVDADSGDNSRLEYRLTSTTPN-------F 529

Query: 523 QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582
            F IN  TG I     LDRE++  Y   V ARD G P +S +  + ++V+DVNDN P F 
Sbjct: 530 PFAINNSTGWIVVAAELDRESVDFYNFGVEARDQGYPVMSSSASISMTVLDVNDNNPEFT 589

Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP-KDREEGSFVIDPASGVIRT 641
           Q+ Y   + EDA VGTSV  V A D D+  N  + Y++     R   S       G+I  
Sbjct: 590 QKAYYMRLNEDAAVGTSVLTVSAVDQDI--NSVVTYQISSGNTRNRFSITSQSGGGLITL 647

Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701
              LD +    + L   A DG       T  V + + D N   PVF+S   T  I+E+ P
Sbjct: 648 ALPLDYKLERQYVLTITASDG---TLFDTAKVFVNVTDANTHRPVFQSSHYTVNINEDRP 704

Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761
           +GTT+  I A D D G NA + Y +   D    F ++     D   + T ++LDYE  + 
Sbjct: 705 MGTTVVLISATDEDTGENARITYFM--DDSIPQFDID----PDSGAVTTQMELDYED-QV 757

Query: 762 KYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA 818
            Y L I A     P   +   +EILV DVNDN P       + +  +D        +V A
Sbjct: 758 SYTLAITARDNGIPQKSDTTYLEILVNDVNDNGPRFLRDHYVGSVMEDVPVFTSVVQVSA 817

Query: 819 YDAD--VTDKLQYRILSGNNANLILLNETTGSM--TLSPQLNTNVPKLATMEVSVTDGVN 874
            D D  +  ++ Y    G + +   + E+T  +  TL      NVP       +V  GV 
Sbjct: 818 TDRDSGLNGRVFYTFQGGEDGDGDFIIESTSGIVRTLRRLDRENVPVYNLQAFAVDKGVP 877

Query: 875 EIKAMMQLSVRLI 887
            +K  + + V ++
Sbjct: 878 ALKTPVNIHVTIL 890



 Score =  215 bits (526), Expect = 1e-53
 Identities = 156/505 (30%), Positives = 235/505 (46%), Gaps = 25/505 (4%)

Query: 381 PGTPVVTLTATDADED--NRLHYEITG-GNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437
           PG P + L A DADE    RL Y I    ++R           G ++  + LD + +  +
Sbjct: 176 PGRPSLVLKAVDADEGEAGRLEYFIEALFDSRSNSLFAVDPANGAVSTVEVLDRETKDTH 235

Query: 438 VLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495
           V  V+A D G    TAM  + IT  D N++ PVFE   Y  ++ E+  IG  VL V ATD
Sbjct: 236 VFRVTAVDHGAPRRTAMATLTITVSDTNDHNPVFEQQDYKENIRENLEIGYEVLTVRATD 295

Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555
            D  +N  I Y + +   +  V      F I+ ++G I T  L+DRE +  Y+L V A D
Sbjct: 296 GDAPVNGNILYRIINGNGSNDV------FEIDSRSGVIRTRGLVDREQVEAYMLLVEAND 349

Query: 556 GG--VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613
            G      S T  V I V D NDN P F ++ Y   + ED    T + QV ATD D G N
Sbjct: 350 QGRDPGPRSATATVHIVVEDDNDNAPQFSEKRYVVQVPEDMAPNTEILQVTATDEDRGSN 409

Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS-TVI 672
             +H+ +       G F ID  +G +     LD E+   + L+  A DGG PP S+ + +
Sbjct: 410 AVVHFSI-MSGNTRGQFYIDAQTGKMDLVSHLDYEANKEYTLRIRAQDGGRPPLSNISGL 468

Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732
           V +++ D+ND+ P+F S      + EN P+G +I  I+A D D G N+ + Y +     +
Sbjct: 469 VTVQVLDVNDNAPIFVSTPFQATVLENVPLGYSIIHIQAVDADSGDNSRLEYRLTSTTPN 528

Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVND 789
             F++    G     +V   +LD ES    Y   + A     P + +   + + V DVND
Sbjct: 529 FPFAINNSTG----WIVVAAELDRESV-DFYNFGVEARDQGYPVMSSSASISMTVLDVND 583

Query: 790 NAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGS- 848
           N P            +D         V A D D+   + Y+I SGN  N   +   +G  
Sbjct: 584 NNPEFTQKAYYMRLNEDAAVGTSVLTVSAVDQDINSVVTYQISSGNTRNRFSITSQSGGG 643

Query: 849 -MTLSPQLNTNVPKLATMEVSVTDG 872
            +TL+  L+  + +   + ++ +DG
Sbjct: 644 LITLALPLDYKLERQYVLTITASDG 668



 Score =  132 bits (319), Expect = 1e-28
 Identities = 64/169 (37%), Positives = 96/169 (56%), Gaps = 16/169 (9%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            +TC+C E +TG +C+       C       +CR+G  CV    GG  C+ C     Y   
Sbjct: 1220 YTCECLEDYTGEHCQLSSRSGRCAP----GVCRNGGTCVNLLVGGFKCE-CP-SGGYEKP 1273

Query: 1102 VCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVS 1161
             CE+  R+FP  SFLTF GL++R    L L FAT+  +GLLLYNGR+NE+HDF+A+E++ 
Sbjct: 1274 YCEMTTRNFPPHSFLTFKGLRQRFHFTLSLTFATREPNGLLLYNGRFNEKHDFIAMEIID 1333

Query: 1162 SEAGRGGGPGLRFSFSLGGGKSEIT--VEGNVGDGSWHTVEIEYFNRTI 1208
             +        ++ ++S G  K+ +   + G V DG WH VE+ Y+N+ +
Sbjct: 1334 EQ--------IQLTYSAGETKTTVAPRIPGGVSDGQWHVVEVHYYNKGV 1374



 Score =  122 bits (294), Expect = 1e-25
 Identities = 102/337 (30%), Positives = 156/337 (46%), Gaps = 38/337 (11%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I V D ND+ P F    Y  SV E     T+V+ + ATD+D G N  V YT +      
Sbjct: 780  EILVNDVNDNGPRFLRDHYVGSVMEDVPVFTSVVQVSATDRDSGLNGRVFYTFQ------ 833

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
               ED               F I+  SG + T   LDRE V  Y +   A D+  P    
Sbjct: 834  -GGEDGDGD-----------FIIESTSGIVRTLRRLDRENVPVYNLQAFAVDKGVPA--- 878

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            L +   IHV I+D NDN P F +    + V+E+  +    V+  + ATD D G+N+ I Y
Sbjct: 879  LKTPVNIHVTILDVNDNPPVFEKDELDIMVEENSPI--GLVVGHVSATDPDEGSNAQIMY 936

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             I+ GN    F +D  SG+++ +  LDYE    Y +V++A      SR+    + I + D
Sbjct: 937  QIVEGNIPEVFQLDIFSGELTSLIDLDYETRNEYVIVVQATSAPLVSRAT---VHIKLVD 993

Query: 250  VNDNAP--RFYTSLFQESVS---ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
             NDN P  + +  +F   V+    + P G  I R+ A+D D  V+ +L Y+       GN
Sbjct: 994  KNDNVPVLKNFQIIFNNYVTNKYSSFPSGV-IGRIPAHDPD--VSDQLHYSFE----VGN 1046

Query: 305  VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341
                + ++  +G +  S  LD     +  + ++ +DG
Sbjct: 1047 ELNLVLLNQSTGEIQLSQALDNNRPLEASMRISVSDG 1083



 Score = 85.8 bits (203), Expect = 2e-14
 Identities = 74/241 (30%), Positives = 105/241 (43%), Gaps = 35/241 (14%)

Query: 1722 PGSSGRATRTCDETKDVPWQDPDMFNCTTATFYQLRKQLHKIETGELTMNTFVGVRVAAD 1781
            P S G A R CDE K   W  P +FNCT++TF +L+    K       ++     + AA 
Sbjct: 2055 PPSPGTAIRHCDEHKG--WLPPSLFNCTSSTFSRLQTLAEKFSHNASLLDAGHVRQTAAM 2112

Query: 1782 LSTACANTPRLYGADVVVAEGILLELMDYELRQAGLNLTHSQDKDYVRNLLKSTNTILNV 1841
            L+ A  +T   YG+DV V   ++  L+ +E  Q G NLT +QD  +   + + T+T  + 
Sbjct: 2113 LANATLHTETFYGSDVKVVYRLVRSLLQHESHQQGFNLTATQDVHFT-EVTRRTHTHTHT 2171

Query: 1842 EYERE-----WKRIR-----------------------ELTGH---GAELLVQKFDEYIA 1870
               R      W+ IR                       EL  H   G   L++ F+EY  
Sbjct: 2172 HTHRWGRGVCWELIRPVNTQNLVRVSSAVLSPDTRPHWELIQHSEGGTAALLRCFEEYTN 2231

Query: 1871 VLAESQHDTYTSPFEIVTKDVVISVDTVTSESIYGFEPTQLNRL-NVDSYTTERVVALPD 1929
             LA++   TY SPF IVT  +VISVD +      G    +   L        E  V LPD
Sbjct: 2232 TLAQNMRKTYLSPFTIVTPHIVISVDRLKKLGFAGARLPRFQALRGPRPADLETTVTLPD 2291

Query: 1930 T 1930
            +
Sbjct: 2292 S 2292



 Score = 81.8 bits (193), Expect = 2e-13
 Identities = 67/234 (28%), Positives = 104/234 (44%), Gaps = 31/234 (13%)

Query: 1    MSVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEY 60
            +  P  IH  + +LD ND+ PVFE  + +  V E +  G  V  + ATD D G NA++ Y
Sbjct: 879  LKTPVNIH--VTILDVNDNPPVFEKDELDIMVEENSPIGLVVGHVSATDPDEGSNAQIMY 936

Query: 61   TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT 120
             I                       + +VF++D  SG L +   LD E    Y ++V+AT
Sbjct: 937  QI-------------------VEGNIPEVFQLDIFSGELTSLIDLDYETRNEYVIVVQAT 977

Query: 121  DQASPVSDRLSSTATIHVNIIDDNDNYPQFS--EKTYTVSVDEDISVTDNPVIAKIKATD 178
                  S  L S AT+H+ ++D NDN P     +  +   V    S   + VI +I A D
Sbjct: 978  ------SAPLVSRATVHIKLVDKNDNVPVLKNFQIIFNNYVTNKYSSFPSGVIGRIPAHD 1031

Query: 179  ADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232
             DV  +  + Y+   GN      ++  +G++ L + LD  +     + I   DG
Sbjct: 1032 PDV--SDQLHYSFEVGNELNLVLLNQSTGEIQLSQALDNNRPLEASMRISVSDG 1083



 Score = 57.6 bits (133), Expect = 5e-06
 Identities = 32/78 (41%), Positives = 42/78 (53%), Gaps = 10/78 (12%)

Query: 1032 LFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQG 1091
            +FRPI+P+    C+CP GFTG  CET +     +  G   +CRS       REGG  C+ 
Sbjct: 1172 MFRPIHPIAGLRCRCPTGFTGDYCETEIDLCYSKPCGAHGVCRS-------REGGYTCE- 1223

Query: 1092 CSIDAAYTTAVCELRARS 1109
            C  D  YT   C+L +RS
Sbjct: 1224 CLED--YTGEHCQLSSRS 1239



 Score = 48.0 bits (109), Expect = 0.004
 Identities = 43/147 (29%), Positives = 71/147 (48%), Gaps = 17/147 (11%)

Query: 2176 LKKPIRLQIWLDINRETFGSRTNPQCVHWS--TLRGSGEWSRVGCHTEIDYDWSPYSEEP 2233
            L KPI +Q  L    E    R+ P CV W+   L G G WS  GC  E+ +  S +    
Sbjct: 2386 LDKPISVQFRLVATEE----RSKPICVLWNHTILGGRGGWSAKGC--EVVFRNSSH---- 2435

Query: 2234 LLINCTCNHLSTFAVLVDEVDVEFIPEPSLLESVTSYTAFSISLPLLLTSWAALCLIRGG 2293
              I+C C H+++FAVL+D    E      L   V +++   ++L  LL +   L  +R  
Sbjct: 2436 --ISCQCYHMTSFAVLMDVSRRE--NGEILPIKVLTWSTVGVTLGFLLLTTVFLLCLRAM 2491

Query: 2294 AATVSNSIHKHLIFSVFMAELLYLIAL 2320
                  SI  +   ++F++EL++++ +
Sbjct: 2492 KCN-KTSIINNGATALFLSELIFILGI 2517


>UniRef50_A7RKF4 Cluster: Predicted protein; n=2; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 2493

 Score =  617 bits (1525), Expect = e-174
 Identities = 370/1118 (33%), Positives = 580/1118 (51%), Gaps = 73/1118 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            INVLD ND+ P+FE   Y A + E  S G  VL ++A+D D G N EV+Y I       L
Sbjct: 116  INVLDVNDNGPIFERNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCI-------L 168

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N +                F I   SGA+     LDREKV  YT+ V+A DQ +P     
Sbjct: 169  NSDGD-----------NSAFSIGEVSGAVTVMKKLDREKVPTYTLQVQAQDQGNPPR--- 214

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S+T T+ + ++D ND  PQFS+K Y+ ++ ED+ V  N ++  ++ATD D G+N  + + 
Sbjct: 215  SATVTVKITLLDVNDCTPQFSKKVYSATIREDVPV--NQLVTTVRATDCDQGSNGEVFFE 272

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I+ GN    FSI+ ++G+V + + LDYE +  + L++ AQD G P   N T + I + DV
Sbjct: 273  IVSGNDMNFFSINRINGEVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDV 332

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDNAP+F +S FQ  + EN  +G    RVQAYD D G N E+T++    D      LP +
Sbjct: 333  NDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKDHGTNGEITFSFMQND------LPFS 386

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            I+  +G +    +LDRE   K+   + A D G P +  TA               F   +
Sbjct: 387  INENTGGISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEE 446

Query: 371  YEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGR-FSITSQNGRGLITVAQP 428
            Y   +AE+   GT V+ + A D D     + Y I   +   R F I   N +GLIT++  
Sbjct: 447  YHTSIAENSRWGTSVLQVKAIDPDSGPTNVVYSIVSSSGHDRCFRI---NPQGLITLSCT 503

Query: 429  LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
            L++  +  YV +VSA+D G  S TA+V +N+TD+N +AP F+   Y+A V EDA +GT+V
Sbjct: 504  LNYNTKHVYVFSVSASD-GMLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSV 562

Query: 489  LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
            L V ATD D G NA+I+YS+++ +          +F ++  TG I T   LDRE +  Y 
Sbjct: 563  LTVLATDRDTGSNAKISYSIATLVP---------EFSVDETTGVIKTAGSLDREKVDTYR 613

Query: 549  LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
              VTA D G+P L   + V I + DVNDN+PVF +  Y A + ED   G  V +V A+DA
Sbjct: 614  FEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDA 673

Query: 609  DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
            D+G N +I Y        +G+F ID   G+IRT K LDRE++  ++L  VA D GTPP  
Sbjct: 674  DIGKNAQIIYSFASNGDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQ 733

Query: 669  STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
            ++V V + +ED+ DSPP+FE       + E++P  + +  ++A   D  P   + YSI  
Sbjct: 734  ASVKVKVILEDVKDSPPLFEKPLYEVTVPEDTPPRSPVITVKAKSQDLSPETGMMYSIVR 793

Query: 729  GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVN 788
            G+    F +    G+    + T++ LDYE+ + +Y L +RA   P + +  V + + D+N
Sbjct: 794  GNSPQVFDINPNTGA----IQTLMKLDYET-QSEYRLTVRATLSPFFTETTVMVYLKDIN 848

Query: 789  DNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGS 848
            DN PV++ F +  N  +   P     ++PAYD DV+DKL ++++ GN    + LN T+G 
Sbjct: 849  DNTPVLEAFHMNINVQEGKVPPEARYKIPAYDPDVSDKLTFKVMEGNAKEWVTLNATSGE 908

Query: 849  MTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQF 908
            ++++ +L     K A ++++VTDG+    A   + +  +T EM+  SI + ++DM   +F
Sbjct: 909  LSVNKKL-IQASKPANIKIAVTDGLRTASATGSIMMTSVTTEMIQQSIQLEIDDMEVLEF 967

Query: 909  LSPLLGFFIDGLAAIIPCPKENIYIFSVQ-------DDTDVTGNILNVSFSARRPDAEVG 961
             +       + ++ I+ C  + + +F +           D +   L +    R+ + +  
Sbjct: 968  FNTAYEKLRESVSQIVKCKPDQVLMFDITSRVILPVSSADYSKTRLTIWLVLRKKNEKEA 1027

Query: 962  VAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPC-----LNFEECLTV 1016
              G    ++  + +R  +YLHR  +A+   + ++ F D++C  +PC      ++ +C T 
Sbjct: 1028 FVG----YFDASFVRYVIYLHREQIAKEVGINLMAFPDDVCSKKPCNYLKPNSYYDCNTY 1083

Query: 1017 LKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRS- 1075
              F      ++S  V+FR +     F C CP  + G +C+T L        G+   C S 
Sbjct: 1084 TYFSGEPQVLSSLKVVFRTVPVDMKFNCSCPADYRGQDCDTHLNLCYSNPCGNHGECVSV 1143

Query: 1076 --GSQCVARREGGILCQGCSIDAAYTTAVCELRARSFP 1111
              G  C  + +      G   +A  T   C L+ R  P
Sbjct: 1144 EQGFYCRCKADR----VGSRCEANVTRDFCPLKPRELP 1177



 Score =  458 bits (1130), Expect = e-127
 Identities = 284/938 (30%), Positives = 442/938 (47%), Gaps = 96/938 (10%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDG---------DGSICRSGSQCVARREGGILCQGC 1092
            F C+C     G  CE  +T+  C +             + C +G+QC+ +  GG  C  C
Sbjct: 1147 FYCRCKADRVGSRCEANVTRDFCPLKPRELPKVNQMKWNPCMNGAQCINQPGGGFGCL-C 1205

Query: 1093 SIDAAYTTAVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERH 1152
                   T  CEL   SF    +  F  L ++ R+H+ L+F T  +  LLLYNG++N++ 
Sbjct: 1206 EDSNKADTPFCELTTLSFRDGDYAAFTALSQKWRLHISLQFTTLQSDALLLYNGQFNDKQ 1265

Query: 1153 DFLALELVSSEAGRGGGPGLRFSFSLGGGKSEIT--VEGNVGDGSWHTVEIEYFNR---- 1206
            DF+A+EL         G  +RF+ S GG  +  T  V+G + DG WH++   Y N+    
Sbjct: 1266 DFIAIEL--------SGGQIRFTVSTGGTPASATSRVDGGLNDGRWHSLTAVYKNKHVIL 1317

Query: 1207 -----------TITMILDDCDKVLSLAGAADFGLK---YACANFTRKVLPARCEIPTETC 1252
                       T  +I+DDC     LA A  FG +   Y CA   R           +  
Sbjct: 1318 TSVHQTQTSPNTAIVIIDDC----KLAVAVQFGTQEGSYGCAAAKRL---------NQQA 1364

Query: 1253 HRFLDLTGPLQIGGLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPE 1312
             R L LT PL +GGL ++ S + + +K + GC+ +  IDHK +DL + +   GT   C  
Sbjct: 1365 ARSLQLTSPLMLGGLHSLRSEYPITSKRYTGCLRNVSIDHKRLDLAAPIWKRGTSPKCSI 1424

Query: 1313 KRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLRP 1372
            K   C ++PC  G  C++ W TY+C C E + GK C        RF G  +L  N     
Sbjct: 1425 KVDFCRNSPCKRG-NCTNTWGTYLCRCPENYGGKQCDKEMKSTMRFIGQSILIKNYRTTS 1483

Query: 1373 IQLPWLNALSIRTRQ----------RDAFVMS-----IQLKSGLLHYSYNGE-TMYLPMA 1416
            I+LPW  +L  RTR+          R  F ++     +Q+ +G L Y +N + T+ L   
Sbjct: 1484 IKLPWSQSLMFRTRKSLGILIETRFRLCFYLNKNTLDLQVVNGRLSYQFNQQLTVNLSQL 1543

Query: 1417 TLSDGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIGG---LDTTAG 1473
             + DGAWH +++ WL   + VT DY  +         K++  +  ++++GG   L+T+A 
Sbjct: 1544 RVDDGAWHHVDVTWLRGMVRVTGDYIYQATATHQ-GEKLE--FTSELIMGGRQSLNTSAP 1600

Query: 1474 LLASDVGF-FEGCIQD-----VRIGTAQSLLNRPTVRENVRDGCQSRADCMLSICPPYSK 1527
               + +   F GC+       + +  +Q   ++ T +++V  GC   + C  S C     
Sbjct: 1601 QPKAYIEEGFVGCMMGKWYFCIAVDGSQIDTSQAT-KQSVFTGCSMPSHCQSSPCLGGGT 1659

Query: 1528 CVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARC-VPDQTPKGYSCACEPGYTLTTSGC 1586
            CV  WD+ +C C  G VG +C + C+L PC    C +   TPKGY C C P YT     C
Sbjct: 1660 CVEGWDTFSCRCRPGYVGKRCTNVCDLKPCQNGNCELSSATPKGYKCKCPPQYT--GEYC 1717

Query: 1587 IESGKEECPGGWWGGS---ACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLP 1643
                +  C   ++  S    CGPC C V   ++P CNK  G+C+C   HY+     ECL 
Sbjct: 1718 ETRKETPCQDKFFSASNIGLCGPCNCPVGANFNPVCNKTTGECYCNPYHYRSHKGNECLK 1777

Query: 1644 CQCYAAGSENSSCEAATGQCHCRPG------VIGRACDACANAYAEVTPNSGCEVVYDGC 1697
            C C   GS +  C  + GQC C  G      VIGR CD C +  +E+T   GC V+   C
Sbjct: 1778 CNCEEIGSLSLQCRVSDGQCPCIKGSSTGARVIGRRCDRCEDHQSEITAGKGCVVINTSC 1837

Query: 1698 PRSFAGGVWWPRTKFGVETITDCPPGSSGRATRTCDETKDVPWQDPDMFNCTTATFYQLR 1757
            PRS A  +WW R  F       CP G+SG A R CD+ K   WQ PD+ +C + +F  LR
Sbjct: 1838 PRSIAEDIWWKRGAFDKTAEQKCPFGASGTARRICDKNKG--WQKPDLMDCVSNSFLNLR 1895

Query: 1758 KQLHKIETGELTMNTFVGVRVAADLSTACANTPRLYGADVVVAEGILLELMDYELRQAGL 1817
            K+L ++E G+L  +  + + +A  L  A     RLY  D+ +A   +  L DYE +Q   
Sbjct: 1896 KKLKRLEEGKLLWSPSIAMDLARQLDLAITLATRLYPNDIDIALKAITVLFDYESQQNES 1955

Query: 1818 NLTHSQDKDYVRNLLKSTNTILNVEYEREWKRIRELTGHGAELLVQKFDEYIAVLAESQH 1877
             L  +++ ++ + L++S + + N E +  W  ++  +   A+L+ +K + +   LA +  
Sbjct: 1956 TLVSAKNHEFAQILVQSASMLFNAENKNVWSVVQRNSAGTADLM-EKMENFSGTLANNLA 2014

Query: 1878 DTYTSPFEIVTKDVVISVDTVTSESIYGFEPTQLNRLN 1915
                + +    + ++     +T   +    P  +   N
Sbjct: 2015 HLKRARYRRNVESIIPPYTVITPNILMELHPVTIRNFN 2052



 Score =  371 bits (912), Expect = e-100
 Identities = 264/841 (31%), Positives = 414/841 (49%), Gaps = 55/841 (6%)

Query: 18  DHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXX 77
           ++ P F   Q +ASV E A  GT V T+ A+D D G N  + Y+        ++P     
Sbjct: 15  NNPPQFSRLQEDASVSEDAEVGTVVATVSASDPDSGSNGMIRYS--------MSPSQNLM 66

Query: 78  XXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIH 137
                       F ID  +G + T+  LDRE + R+   VKA D   P    L     + 
Sbjct: 67  SATY--------FSIDQITGVITTKRGLDREFLDRHFFRVKAEDGGEP---SLEGYMDLT 115

Query: 138 VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN-T 196
           +N++D NDN P F    Y   + ED S+ D   +  ++A+DAD G+N  ++Y I+  +  
Sbjct: 116 INVLDVNDNGPIFERNIYAADIPEDKSIGD--FVLAVRASDADSGSNGEVKYCILNSDGD 173

Query: 197 QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256
              FSI  +SG V+++K LD E+V +Y L ++AQD G+P RS T  + I + DVND  P+
Sbjct: 174 NSAFSIGEVSGAVTVMKKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQ 233

Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316
           F   ++  ++ E+VP+   +  V+A D D+G N E+ + +     +GN     +I+  +G
Sbjct: 234 FSKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFFEIV----SGNDMNFFSINRING 289

Query: 317 WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376
            V    +LD E    + LLVTA D G P      T              F+   ++  + 
Sbjct: 290 EVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIP 349

Query: 377 EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436
           E+   G     + A   D+D+  + EIT    +     +     G I++ + LD ++  +
Sbjct: 350 ENYAVGQEFYRVQA--YDKDHGTNGEITFSFMQNDLPFSINENTGGISIKEELDREKVPK 407

Query: 437 YVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494
           +   + A D G   +  TA + I + D N+  P F    Y  S+ E++  GT+VL V A 
Sbjct: 408 FTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAI 467

Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554
           D D G    + YS+ S       + HD+ F INPQ G IT +  L+  T   Y+ +V+A 
Sbjct: 468 DPDSG-PTNVVYSIVSS------SGHDRCFRINPQ-GLITLSCTLNYNTKHVYVFSVSAS 519

Query: 555 DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614
           DG    LS T  V ++V D N + P FK++ Y+A + EDA +GTSV  V ATD D G N 
Sbjct: 520 DG---MLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNA 576

Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674
           +I Y +     E   F +D  +GVI+T  +LDRE V T+  +  A D G P   +   V+
Sbjct: 577 KISYSIATLVPE---FSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVY 633

Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-KGGDDSN 733
           I I D+ND+ PVF        + E+   G  + E+ A D D G NA + YS    GD   
Sbjct: 634 IHIADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDADIGKNAQIIYSFASNGDGQG 693

Query: 734 SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDN 790
           +F++++ QG     + T+  LD E+   +YEL + A    +PP    V+V++++ DV D+
Sbjct: 694 TFTIDSTQGI----IRTLKPLDRET-IPEYELTVVATDQGTPPGQASVKVKVILEDVKDS 748

Query: 791 APVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNNANLILLNETTGS 848
            P+ +         +D  P  P   V A   D++ +  + Y I+ GN+  +  +N  TG+
Sbjct: 749 PPLFEKPLYEVTVPEDTPPRSPVITVKAKSQDLSPETGMMYSIVRGNSPQVFDINPNTGA 808

Query: 849 M 849
           +
Sbjct: 809 I 809



 Score =  309 bits (758), Expect = 9e-82
 Identities = 239/756 (31%), Positives = 349/756 (46%), Gaps = 42/756 (5%)

Query: 145 DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ---FS 201
           +N PQFS      SV ED  V    V+A + A+D D G+N  IRY++      M    FS
Sbjct: 15  NNPPQFSRLQEDASVSEDAEV--GTVVATVSASDPDSGSNGMIRYSMSPSQNLMSATYFS 72

Query: 202 IDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261
           ID ++G ++  + LD E +  +   ++A+DGG PS      L IN+ DVNDN P F  ++
Sbjct: 73  IDQITGVITTKRGLDREFLDRHFFRVKAEDGGEPSLEGYMDLTINVLDVNDNGPIFERNI 132

Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321
           +   + E+  IG  ++ V+A DAD G N E+ Y + + D   +     +I   SG V   
Sbjct: 133 YAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDNSA---FSIGEVSGAVTVM 189

Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381
            +LDRE    Y L V A D G+PPRSAT T              F    Y   + ED P 
Sbjct: 190 KKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPV 249

Query: 382 GTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL 439
              V T+ ATD D+  +  + +EI  GN    FSI   NG   + V Q LD++    + L
Sbjct: 250 NQLVTTVRATDCDQGSNGEVFFEIVSGNDMNFFSINRINGE--VRVKQKLDYEMIGVFNL 307

Query: 440 TVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497
            V+A D G     +   V I + D N+ AP F ++ +   + E+  +G     V A D D
Sbjct: 308 LVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKD 367

Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG 557
            G N +IT+S            +D  F IN  TG I+  + LDRE +  +   + ARD G
Sbjct: 368 HGTNGEITFSF---------MQNDLPFSINENTGGISIKEELDREKVPKFTFGIKARDKG 418

Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617
           VP    T  + I+++D+NDN P F Q+ Y  +I E++  GTSV QV A D D G    + 
Sbjct: 419 VPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSGPT-NVV 477

Query: 618 YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
           Y +      +  F I+P  G+I  +  L+  +   +     A DG     SST +V++ +
Sbjct: 478 YSIVSSSGHDRCFRINP-QGLITLSCTLNYNTKHVYVFSVSASDG---MLSSTALVYVNV 533

Query: 678 EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL 737
            D N   P F+    +  + E++ +GT++  + A D D G NA + YSI        FS+
Sbjct: 534 TDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSI--ATLVPEFSV 591

Query: 738 ETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVM 794
           +   G  K    T   LD E     Y   + A     P L     V I + DVNDN PV 
Sbjct: 592 DETTGVIK----TAGSLDREKV-DTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVF 646

Query: 795 KDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQ--YRILS-GNNANLILLNETTGSM-T 850
                     +D  P G    V A DAD+    Q  Y   S G+      ++ T G + T
Sbjct: 647 LKPSYEAKVREDIRPGGRVIEVSASDADIGKNAQIIYSFASNGDGQGTFTIDSTQGIIRT 706

Query: 851 LSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886
           L P     +P+     V+   G    +A +++ V L
Sbjct: 707 LKPLDRETIPEYELTVVATDQGTPPGQASVKVKVIL 742



 Score =  287 bits (705), Expect = 2e-75
 Identities = 216/708 (30%), Positives = 338/708 (47%), Gaps = 48/708 (6%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +I +LD ND +P F  + Y A++RE       V T++ATD D G N EV +  E+V+ + 
Sbjct: 221 KITLLDVNDCTPQFSKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFF--EIVSGND 278

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
           +N                  F I+  +G +  +  LD E +  + +LV A D+  P    
Sbjct: 279 MN-----------------FFSINRINGEVRVKQKLDYEMIGVFNLLVTAQDKGQPF--- 318

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           L +  T+ + +ID NDN PQF    +   + E+ +V       +++A D D G N  I +
Sbjct: 319 LYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQE--FYRVQAYDKDHGTNGEITF 376

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
           + +     + FSI+  +G +S+ + LD E+V  +   I+A+D G P +  T Q+ I + D
Sbjct: 377 SFM--QNDLPFSINENTGGISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLD 434

Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
           +NDN P+F    +  S++EN   G S+++V+A D D G    + Y++     +G+ D   
Sbjct: 435 INDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSG-PTNVVYSIVSS--SGH-DRCF 490

Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            I+P+ G +  S  L+  T+  Y   V+A+DG     S+TA               F   
Sbjct: 491 RINPQ-GLITLSCTLNYNTKHVYVFSVSASDG---MLSSTALVYVNVTDSNTHAPEFKRR 546

Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
            Y  E+ ED   GT V+T+ ATD D  +      +       FS+      G+I  A  L
Sbjct: 547 SYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSIATLVPEFSVDETT--GVIKTAGSL 604

Query: 430 DFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
           D ++   Y   V+ATD G       + V I+I D N+  PVF    Y A V ED   G  
Sbjct: 605 DREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGR 664

Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
           V+ VSA+D+D+G NAQI YS +S    +        F I+   G I T K LDRET+  Y
Sbjct: 665 VIEVSASDADIGKNAQIIYSFASNGDGQGT------FTIDSTQGIIRTLKPLDRETIPEY 718

Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
            LTV A D G P    +  V++ + DV D+ P+F++ LY   + ED    + V  V A  
Sbjct: 719 ELTVVATDQGTPPGQASVKVKVILEDVKDSPPLFEKPLYEVTVPEDTPPRSPVITVKAKS 778

Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
            D+     + Y +  +      F I+P +G I+T   LD E+ + + L    +     P 
Sbjct: 779 QDLSPETGMMYSI-VRGNSPQVFDINPNTGAIQTLMKLDYETQSEYRL---TVRATLSPF 834

Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
            +   V + ++DIND+ PV E+  +   + E         +I A+DPD
Sbjct: 835 FTETTVMVYLKDINDNTPVLEAFHMNINVQEGKVPPEARYKIPAYDPD 882



 Score =  239 bits (585), Expect = 8e-61
 Identities = 159/432 (36%), Positives = 222/432 (51%), Gaps = 21/432 (4%)

Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523
           N  P F      ASV EDA +GT V  VSA+D D G N  I YS+S   +  +  +    
Sbjct: 15  NNPPQFSRLQEDASVSEDAEVGTVVATVSASDPDSGSNGMIRYSMSPSQNLMSATY---- 70

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583
           F I+  TG ITT + LDRE +  +   V A DGG PSL    D+ I+V+DVNDN P+F++
Sbjct: 71  FSIDQITGVITTKRGLDREFLDRHFFRVKAEDGGEPSLEGYMDLTINVLDVNDNGPIFER 130

Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK 643
            +Y A+I ED  +G  V  V A+DAD G NG + Y +   D +  +F I   SG +   K
Sbjct: 131 NIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDNSAFSIGEVSGAVTVMK 190

Query: 644 ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703
            LDRE V T+ L+  A D G PP+S+TV V I + D+ND  P F     +  I E+ P+ 
Sbjct: 191 KLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPVN 250

Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY 763
             +  +RA D D+G N  V + I  G+D N FS+    G    E+     LDYE     +
Sbjct: 251 QLVTTVRATDCDQGSNGEVFFEIVSGNDMNFFSINRING----EVRVKQKLDYEM-IGVF 305

Query: 764 ELVIRA---ASPPLWNDVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFPVG-PFGRVP 817
            L++ A     P L+N   V+I + DVNDNAP  V   FQ +     + + VG  F RV 
Sbjct: 306 NLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMI---PENYAVGQEFYRVQ 362

Query: 818 AYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN-TNVPKLATMEVSVTD-GVNE 875
           AYD D     +       N     +NE TG +++  +L+   VPK  T  +   D GV  
Sbjct: 363 AYDKDHGTNGEITFSFMQNDLPFSINENTGGISIKEELDREKVPKF-TFGIKARDKGVPF 421

Query: 876 IKAMMQLSVRLI 887
            +   Q+++ L+
Sbjct: 422 KEGTAQITITLL 433



 Score =  235 bits (574), Expect = 2e-59
 Identities = 190/637 (29%), Positives = 282/637 (44%), Gaps = 25/637 (3%)

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
           R   +N P+F       SVSE+  +G  +  V A D D G N  + Y+M+      +   
Sbjct: 11  RAPTNNPPQFSRLQEDASVSEDAEVGTVVATVSASDPDSGSNGMIRYSMSPSQNLMSATY 70

Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
             +ID  +G + T   LDRE   ++   V A DGG+P                     F 
Sbjct: 71  -FSIDQITGVITTKRGLDREFLDRHFFRVKAEDGGEPSLEGYMDLTINVLDVNDNGPIFE 129

Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITS-QNGRGLITVA 426
              Y  ++ ED+  G  V+ + A+DAD  +    +    N+ G  S  S     G +TV 
Sbjct: 130 RNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDNSAFSIGEVSGAVTVM 189

Query: 427 QPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
           + LD ++   Y L V A D G   RS T  V+I + D N+  P F    Y+A++ ED P+
Sbjct: 190 KKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPV 249

Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRET 543
              V  V ATD D G N ++ +        E V+ +D  F  IN   G +   + LD E 
Sbjct: 250 NQLVTTVRATDCDQGSNGEVFF--------EIVSGNDMNFFSINRINGEVRVKQKLDYEM 301

Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
           +  + L VTA+D G P L + T V+I+++DVNDN P F    +   I E+  VG    +V
Sbjct: 302 IGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRV 361

Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
            A D D G NG I +     D     F I+  +G I   + LDRE V        A D G
Sbjct: 362 QAYDKDHGTNGEITFSFMQNDL---PFSINENTGGISIKEELDREKVPKFTFGIKARDKG 418

Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
            P +  T  + I + DIND+PP F  +     I+ENS  GT++ +++A DPD GP  VV+
Sbjct: 419 VPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSGPTNVVY 478

Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTM-VDLDYESPRKKYELVIRAASPPLWNDVRVEI 782
             +        F +   QG     L+T+   L+Y + +  Y   + A+   L +   V +
Sbjct: 479 SIVSSSGHDRCFRINP-QG-----LITLSCTLNYNT-KHVYVFSVSASDGMLSSTALVYV 531

Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILL 842
            VTD N +AP  K         +D         V A D D     +             +
Sbjct: 532 NVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSIATLVPEFSV 591

Query: 843 NETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKA 878
           +ETTG +  +  L+         EV+ TD G+ ++KA
Sbjct: 592 DETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKA 628



 Score = 74.1 bits (174), Expect = 5e-11
 Identities = 48/166 (28%), Positives = 91/166 (54%), Gaps = 20/166 (12%)

Query: 2159 NATGVGKKMYRSLSGIRLKKPIRLQIWLDINRETFGSRTNPQCVHWS----TLRGSGEWS 2214
            N+  V  KM   +  ++L +PI +  +   NR+   +R+   CV W+      RG G WS
Sbjct: 2142 NSDVVSVKM-PGMEDVQLAEPIHITFY---NRQV--NRSEYLCVFWNYSVPNTRGGG-WS 2194

Query: 2215 RVGCHTEIDYDWSPYSEEPLLINCTCNHLSTFAVLVDEVDVEFIPEPSLLESVTSYTAFS 2274
              GC   I  +W+  +       C CNH+++FAVL D +++EF P+ +    + +Y   +
Sbjct: 2195 TNGCR-RIAINWTHTT-------CACNHMTSFAVLSD-LNLEFPPQVAFALRIGTYIGIA 2245

Query: 2275 ISLPLLLTSWAALCLIRGGAATVSNSIHKHLIFSVFMAELLYLIAL 2320
            +S+ +LL ++ +   +RG   + +N IHK+L+ ++ +AE+++L  +
Sbjct: 2246 VSVAILLIAFVSFVCLRGLKKSNANDIHKNLVAAIVIAEIIFLAGI 2291


>UniRef50_Q16QV0 Cluster: Cadherin; n=10; Eukaryota|Rep: Cadherin -
            Aedes aegypti (Yellowfever mosquito)
          Length = 2413

 Score =  491 bits (1211), Expect = e-136
 Identities = 401/1390 (28%), Positives = 636/1390 (45%), Gaps = 117/1390 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            ++V D ND++P+FE   Y  S+ E    G++++ L A D D G N ++ Y++     D +
Sbjct: 557  LHVQDENDNTPMFESNPYSFSLAENIEKGSSIMKLTARDSDSGSNGDIRYSLSTEVGDIV 616

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N                 +F ID  +G + T   LD+EK   Y   V ATD   P   + 
Sbjct: 617  N-----------------IFDIDAYTGWITTLVPLDKEKREDYKFQVIATDNGQP---KH 656

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S+  T+ + + D ND  P F E  Y  SV ED       V+ +I+ TD DV   + I Y 
Sbjct: 657  STRTTVIIRLKDYNDCPPTFKESHYKASVSED--ALPGTVVLQIETTDKDVDLKTNIEYY 714

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            II G+   QF I + SG+V +VKTLD E +  Y L +   DG   S +N +   + + D 
Sbjct: 715  IISGDPLSQFQIKN-SGEVFVVKTLDRESISQYELGVIVTDGKFTSTANIS---VTVLDA 770

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN P      ++E +SE V  G  ++++QA D DE  N+ L + +T     GN      
Sbjct: 771  NDNPPYCLKYRYREQLSEGVHPGTYVLQIQANDIDEPANSRLRFYLT-----GNGAEDFN 825

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            +D  SG + T+ QLDRETQ+K+ L+    D   P    ++               F    
Sbjct: 826  LDKDSGQLKTARQLDRETQSKFHLVAHVQDRDHPGWECSSQIEITITDLNDNPPDFSMNP 885

Query: 371  YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
            Y V L ED   GT V  + ATDAD   + ++ Y     + R  F I   +G  ++T+A+P
Sbjct: 886  YSVTLPEDAEVGTLVTKIHATDADIGINRKIKYSFID-SYRDHFKIAPDSG--IVTLAKP 942

Query: 429  LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
            LD + +  Y LTV ATD G    S++A + +N+ D N+  P F +  Y ASV E++ IGT
Sbjct: 943  LDREVKAVYNLTVRATDQGKPSLSNSAFLVVNVQDINDNPPEFTSKHYFASVLENSSIGT 1002

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
             VL V AT  D GINA+ITYS+     NE      ++F ++ +TG +    ++D E    
Sbjct: 1003 EVLRVLATSKDTGINAEITYSIIG--GNE-----HRKFAMHNKTGVLYLADVVDYERAKD 1055

Query: 547  YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
            Y LT+ A DGG P LS+   V ISV D NDN P F    YTA I EDA  G  + Q+ A 
Sbjct: 1056 YFLTIQAVDGGTPPLSNLATVNISVADCNDNPPQFTANSYTATIREDAQKGDKMLQIRAN 1115

Query: 607  DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
            D D G N R+ Y ++  DR  G F I+  +G I     LDRES++++ L+  A D G+P 
Sbjct: 1116 DMDSGENSRVSYRIERGDRM-GQFDIEEDTGYISVAGTLDRESISSYVLEVQARDHGSPS 1174

Query: 667  QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH-YS 725
             S+ V+V+I+I D ND+PP+F S+  T  + E+  IG T+ +    D D  PNA  + + 
Sbjct: 1175 LSTYVLVNIEISDANDNPPLFTSNNYTAVVQEDKQIGFTLLKFEVTDADAAPNAAPYTFD 1234

Query: 726  IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEI 782
            ++ G+D  +F +E + G     ++          +  Y L IR     SPPL++D  V I
Sbjct: 1235 VRSGNDGGAFRIE-QDG-----ILRTASRFNSKIKDTYLLGIRVFDNGSPPLYSDTWVSI 1288

Query: 783  LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRIL--SG---NNA 837
             V + +   PV+    +  N+++D +P G  G+V A D D  D L + +   +G   +  
Sbjct: 1289 KVIEESQYPPVITPLDVSINSFQDEYPGGVIGKVYATDQDQYDTLTFSLAPTAGVLYSPM 1348

Query: 838  NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSIT 897
            NL  ++   G +   P+L+    ++    ++V+DG      +++++V L+T+EML NSI 
Sbjct: 1349 NLFNISRNDGVLYAFPRLDVGDYRV---NITVSDGKFSSYTIVKVAVELVTDEMLANSIV 1405

Query: 898  VRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQ---DDTDVTGNILNVSFSAR 954
            +R   ++ E F+      FI  +   + C  ++I I SVQ   DD ++  + L       
Sbjct: 1406 IRFTKISPESFILSHRKGFIRSVRNSMGCKIKDIIIISVQKSNDDINLIHHRLRRELGTL 1465

Query: 955  RP-DAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEEC 1013
               D    V      +YS   +R+ +  +   +     +Q+     + C+   C++  EC
Sbjct: 1466 HDLDVLFTVRKGQLGYYSAYEIRKAIDDNLEEIEDATKLQIDEVVKSKCLPNFCIH-GEC 1524

Query: 1014 LTVLKFG-NASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSI 1072
               L         +++D   F     V    C C EG+ G  C+  + + S     +   
Sbjct: 1525 EDKLVLDPKIVNPISTDVTSFVSARHVHKMECSCKEGYGGDKCQHAVNECSKSPCPNYKN 1584

Query: 1073 C-----RSGSQCVA-RREGGILC----QGCSIDAAYTTA-VCELRARSFP---VSSFLTF 1118
            C       G  C+   R  G  C      C+ +  YT         +S+    V   +  
Sbjct: 1585 CIPDSSDQGYHCICPERFAGPKCDRDISKCNDETCYTPRNPVSFSGKSYAQYRVEKEIAK 1644

Query: 1119 PGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRGGGPGLRFSFSL 1178
              L+ +  + L+++   Q T  ++   G+     D+  LE+V+          +++ F L
Sbjct: 1645 KNLEDQLMLSLRIR-TVQPTGNIMFSAGKV----DYNILEIVNGV--------VQYRFDL 1691

Query: 1179 GGGKSEITVEG-NVGDGSWHTVEIEYFNRTITMILDDCDKVLSLAGAAD--FGLKYACAN 1235
            G G+  ++V    V DG WH V +E  + +  +I+D+       A   +    L+     
Sbjct: 1692 GSGEGMVSVTSIFVSDGLWHEVRLERESNSARVIVDNKHVASGNAPGVNGVLNLQSDDIF 1751

Query: 1236 FTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNKDFVGCISDFYIDHKFI 1295
            F  +V      +  E   R     G +    L  +P    +     V  +  F       
Sbjct: 1752 FGAEVKQHPTVLGFEDIQR--GYMGCMDDIKLSKVPVPLHMNGASSVASLRRFANVEFSC 1809

Query: 1296 DLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLW-DTYICDCKEGHTGKDCADSTGP 1354
            D +S +   G           C + PC+NG  C+D+    + C C    +G  C +   P
Sbjct: 1810 DASSILVPLGV----------CGTQPCWNGGTCTDIGAGNFECLCHSRFSGPFCKEDLDP 1859

Query: 1355 ----PWRFGG 1360
                P  +GG
Sbjct: 1860 CASSPCLYGG 1869



 Score =  344 bits (846), Expect = 2e-92
 Identities = 248/814 (30%), Positives = 399/814 (49%), Gaps = 44/814 (5%)

Query: 97   GALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT 156
            G L    +LDRE    + + + A   +SP    ++   T+HV   D+NDN P F    Y+
Sbjct: 519  GELRLAKTLDRELKDVHLIAILAETDSSPPLTAVTDV-TLHVQ--DENDNTPMFESNPYS 575

Query: 157  VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG--GNTQMQFSIDSLSGDVSLVKT 214
             S+ E+I    +  I K+ A D+D G+N  IRY++    G+    F ID+ +G ++ +  
Sbjct: 576  FSLAENIEKGSS--IMKLTARDSDSGSNGDIRYSLSTEVGDIVNIFDIDAYTGWITTLVP 633

Query: 215  LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY 274
            LD E+   Y+  + A D G P  S  T ++I ++D ND  P F  S ++ SVSE+   G 
Sbjct: 634  LDKEKREDYKFQVIATDNGQPKHSTRTTVIIRLKDYNDCPPTFKESHYKASVSEDALPGT 693

Query: 275  SIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQL 334
             +++++  D D  +   + Y +   D      +       SG V+    LDRE+ ++Y+L
Sbjct: 694  VVLQIETTDKDVDLKTNIEYYIISGDPLSQFQIK-----NSGEVFVVKTLDRESISQYEL 748

Query: 335  LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394
             V  TDG     ++TA                +  +Y  +L+E   PGT V+ + A D D
Sbjct: 749  GVIVTDG---KFTSTANISVTVLDANDNPPYCLKYRYREQLSEGVHPGTYVLQIQANDID 805

Query: 395  E--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT--VSATDSGGRS 450
            E  ++RL + +TG      F++   +G+  +  A+ LD + + ++ L   V   D  G  
Sbjct: 806  EPANSRLRFYLTGNGAED-FNLDKDSGQ--LKTARQLDRETQSKFHLVAHVQDRDHPGWE 862

Query: 451  DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510
             ++ ++I ITD N+  P F   PY+ ++ EDA +GT V  + ATD+D+GIN +I YS   
Sbjct: 863  CSSQIEITITDLNDNPPDFSMNPYSVTLPEDAEVGTLVTKIHATDADIGINRKIKYSF-- 920

Query: 511  EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570
                  +  +   F I P +G +T  K LDRE  + Y LTV A D G PSLS++  + ++
Sbjct: 921  ------IDSYRDHFKIAPDSGIVTLAKPLDREVKAVYNLTVRATDQGKPSLSNSAFLVVN 974

Query: 571  VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630
            V D+NDN P F  + Y A+++E++ +GT V +V AT  D G+N  I Y +     E   F
Sbjct: 975  VQDINDNPPEFTSKHYFASVLENSSIGTEVLRVLATSKDTGINAEITYSI-IGGNEHRKF 1033

Query: 631  VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690
             +   +GV+     +D E    + L   A+DGGTPP S+   V+I + D ND+PP F ++
Sbjct: 1034 AMHNKTGVLYLADVVDYERAKDYFLTIQAVDGGTPPLSNLATVNISVADCNDNPPQFTAN 1093

Query: 691  CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750
              T  I E++  G  + +IRA+D D G N+ V Y I+ GD    F +E     D   +  
Sbjct: 1094 SYTATIREDAQKGDKMLQIRANDMDSGENSRVSYRIERGDRMGQFDIE----EDTGYISV 1149

Query: 751  MVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVM--KDFQIIFNNYK 805
               LD ES    Y L ++A    SP L   V V I ++D NDN P+    ++  +    K
Sbjct: 1150 AGTLDRES-ISSYVLEVQARDHGSPSLSTYVLVNIEISDANDNPPLFTSNNYTAVVQEDK 1208

Query: 806  DC-FPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLAT 864
               F +  F    A  A       + + SGN+     + E  G +  + + N+ +     
Sbjct: 1209 QIGFTLLKFEVTDADAAPNAAPYTFDVRSGNDGGAFRI-EQDGILRTASRFNSKIKDTYL 1267

Query: 865  MEVSVTD-GVNEIKAMMQLSVRLITEEMLLNSIT 897
            + + V D G   + +   +S+++I E      IT
Sbjct: 1268 LGIRVFDNGSPPLYSDTWVSIKVIEESQYPPVIT 1301



 Score =  289 bits (710), Expect = 6e-76
 Identities = 254/878 (28%), Positives = 401/878 (45%), Gaps = 73/878 (8%)

Query: 8   HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
           H  ++V+D ND+ P FE   Y   + E A+ G  V  + A+D D   +  + YTI     
Sbjct: 141 HVWVSVMDMNDNPPKFEQPSYTCVLSEHATRGQFVTVVSASDPDYIDHDRLTYTI--AQG 198

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVL-VKATDQASPV 126
           + L   D                 I+  SG ++T  ++        T+L V  TD     
Sbjct: 199 NELQTYD-----------------INPVSG-IITLVNMQNFAEKHVTILNVSVTDGV--- 237

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
               +S   + + I+  N + P F    Y V V+E+       ++  +KA D D G    
Sbjct: 238 ---YTSFTRVKITILPANLHNPTFEHLFYDVKVNENQLA--GRLVTTVKAQDKDFGEFGR 292

Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           + Y II    Q  FSID   G++   K LD E+ + Y + I A D G   R+  T + +N
Sbjct: 293 LTYFIISDEIQEYFSIDKDKGEIVTKKKLDREERKLYEVPIMAMDSG--GRAGFTTVRVN 350

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
           + D NDN P F    ++  +  N+    +  RV+A D+D+  NA + Y++ D   +G  +
Sbjct: 351 VGDENDNPPVFLLREYKALIQGNLTTNTTFFRVKAVDSDDNQNAVVKYSIFDSQNSGIKE 410

Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
           L   ID  +G +Y      R     +Q  + A DGG P                     F
Sbjct: 411 L-FGIDENTGGIYLRKSAVRWENQLFQFFIRANDGGVPSLYTDVPIDIYIMSSAENPPVF 469

Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGN-TRGRFSITSQNGRGLITV 425
              +  + L+E   PGT +  L  +    +    Y I        +FSI   N  G + +
Sbjct: 470 EKKEKLLFLSESSLPGTVITRLKLSG---NVTAKYRILSDELEEPQFSI---NNVGELRL 523

Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAP 483
           A+ LD + +  +++ + A        TA+  V +++ D N+  P+FE+ PY+ S+ E+  
Sbjct: 524 AKTLDRELKDVHLIAILAETDSSPPLTAVTDVTLHVQDENDNTPMFESNPYSFSLAENIE 583

Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
            G++++ ++A DSD G N  I YSLS+E+ +         F I+  TG ITT   LD+E 
Sbjct: 584 KGSSIMKLTARDSDSGSNGDIRYSLSTEVGDIV-----NIFDIDAYTGWITTLVPLDKEK 638

Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
              Y   V A D G P  S  T V I + D ND  P FK+  Y A++ EDAL GT V Q+
Sbjct: 639 REDYKFQVIATDNGQPKHSTRTTVIIRLKDYNDCPPTFKESHYKASVSEDALPGTVVLQI 698

Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
             TD DV L   I Y +   D     F I   SG +   K LDRES++ ++L  +  DG 
Sbjct: 699 ETTDKDVDLKTNIEYYIISGD-PLSQFQI-KNSGEVFVVKTLDRESISQYELGVIVTDG- 755

Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
               +ST  + + + D ND+PP          +SE    GT + +I+A+D DE  N+ + 
Sbjct: 756 --KFTSTANISVTVLDANDNPPYCLKYRYREQLSEGVHPGTYVLQIQANDIDEPANSRLR 813

Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV--IRAASPPLWN-DVRV 780
           + +  G+ +  F+L+     D  +L T   LD E+ + K+ LV  ++    P W    ++
Sbjct: 814 FYLT-GNGAEDFNLD----KDSGQLKTARQLDRET-QSKFHLVAHVQDRDHPGWECSSQI 867

Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFP----VGPF-GRVPAYDAD--VTDKLQYRILS 833
           EI +TD+NDN P   DF +  N Y    P    VG    ++ A DAD  +  K++Y  + 
Sbjct: 868 EITITDLNDNPP---DFSM--NPYSVTLPEDAEVGTLVTKIHATDADIGINRKIKYSFID 922

Query: 834 GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
               +  +  + +G +TL+  L+  V  +  + V  TD
Sbjct: 923 SYRDHFKIAPD-SGIVTLAKPLDREVKAVYNLTVRATD 959



 Score =  267 bits (655), Expect = 3e-69
 Identities = 223/780 (28%), Positives = 360/780 (46%), Gaps = 44/780 (5%)

Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS 164
           LD E+   Y +L++ATD  S VS    +   + V + D ND  P+  + +Y ++V E   
Sbjct: 8   LDYEQRQSYELLIRATDSVSGVS----AEVPVSVLVQDVNDCPPEIEQDSYNITVSERAQ 63

Query: 165 VTDNPVIAKIKATDADVGANSAIRYAII--GGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222
                 I K++A D D G N  + YA+     NT   F +D   G + L K+LD+E +  
Sbjct: 64  F--GTAILKVQAKDNDTGINQVVTYALQTDSKNTSEYFHMDPTDGVIYLKKSLDHETLSH 121

Query: 223 YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY 282
           +   + A D G PS S+T  + +++ D+NDN P+F    +   +SE+   G  +  V A 
Sbjct: 122 HHFTVIASDKGVPSLSSTAHVWVSVMDMNDNPPKFEQPSYTCVLSEHATRGQFVTVVSAS 181

Query: 283 DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL-VTATDG 341
           D D   +  LTYT+      GN      I+P SG + T   +    +    +L V+ TDG
Sbjct: 182 DPDYIDHDRLTYTIAQ----GNELQTYDINPVSG-IITLVNMQNFAEKHVTILNVSVTDG 236

Query: 342 GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRL 399
                ++                 F    Y+V++ E++  G  V T+ A D D  E  RL
Sbjct: 237 ---VYTSFTRVKITILPANLHNPTFEHLFYDVKVNENQLAGRLVTTVKAQDKDFGEFGRL 293

Query: 400 HYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINI 459
            Y I     +  FSI    G   I   + LD ++ + Y + + A DSGGR+    V++N+
Sbjct: 294 TYFIISDEIQEYFSIDKDKGE--IVTKKKLDREERKLYEVPIMAMDSGGRAGFTTVRVNV 351

Query: 460 TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAH 519
            D N+  PVF    Y A +  +    TT   V A DSD   NA + YS+  +  N  +  
Sbjct: 352 GDENDNPPVFLLREYKALIQGNLTTNTTFFRVKAVDSDDNQNAVVKYSI-FDSQNSGI-- 408

Query: 520 HDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP 579
             + F I+  TG I   K   R     +   + A DGGVPSL     ++I ++   +N P
Sbjct: 409 -KELFGIDENTGGIYLRKSAVRWENQLFQFFIRANDGGVPSLYTDVPIDIYIMSSAENPP 467

Query: 580 VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639
           VF+++     + E +L GT ++++  +      N    Y +   + EE  F I+   G +
Sbjct: 468 VFEKKEKLLFLSESSLPGTVITRLKLSG-----NVTAKYRILSDELEEPQFSINNV-GEL 521

Query: 640 RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699
           R  K LDRE    H +  +A    +PP ++   V + ++D ND+ P+FES+  +F ++EN
Sbjct: 522 RLAKTLDRELKDVHLIAILAETDSSPPLTAVTDVTLHVQDENDNTPMFESNPYSFSLAEN 581

Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSI--KGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757
              G++I ++ A D D G N  + YS+  + GD  N F ++   G     + T+V LD E
Sbjct: 582 IEKGSSIMKLTARDSDSGSNGDIRYSLSTEVGDIVNIFDIDAYTG----WITTLVPLDKE 637

Query: 758 SPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG 814
             R+ Y+  + A     P       V I + D ND  P  K+     +  +D  P     
Sbjct: 638 K-REDYKFQVIATDNGQPKHSTRTTVIIRLKDYNDCPPTFKESHYKASVSEDALPGTVVL 696

Query: 815 RVPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
           ++   D DV  K  ++Y I+SG+  +   + + +G + +   L+        + V VTDG
Sbjct: 697 QIETTDKDVDLKTNIEYYIISGDPLSQFQI-KNSGEVFVVKTLDRESISQYELGVIVTDG 755



 Score =  257 bits (629), Expect = 4e-66
 Identities = 224/853 (26%), Positives = 369/853 (43%), Gaps = 60/853 (7%)

Query: 13  VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72
           V D ND  P  E   Y  +V E A  GT +L ++A D D G N  V Y ++  + +T   
Sbjct: 39  VQDVNDCPPEIEQDSYNITVSERAQFGTAILKVQAKDNDTGINQVVTYALQTDSKNT--- 95

Query: 73  EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132
                          + F +D   G +  + SLD E ++ +   V A+D+  P    LSS
Sbjct: 96  --------------SEYFHMDPTDGVIYLKKSLDHETLSHHHFTVIASDKGVP---SLSS 138

Query: 133 TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192
           TA + V+++D NDN P+F + +YT  + E    T    +  + A+D D   +  + Y I 
Sbjct: 139 TAHVWVSVMDMNDNPPKFEQPSYTCVLSE--HATRGQFVTVVSASDPDYIDHDRLTYTIA 196

Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252
            GN    + I+ +SG ++LV   ++ +     L +   DG     ++ T++ I I   N 
Sbjct: 197 QGNELQTYDINPVSGIITLVNMQNFAEKHVTILNVSVTDG---VYTSFTRVKITILPANL 253

Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312
           + P F    +   V+EN   G  +  V+A D D G    LTY +   +    +    +ID
Sbjct: 254 HNPTFEHLFYDVKVNENQLAGRLVTTVKAQDKDFGEFGRLTYFIISDE----IQEYFSID 309

Query: 313 PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE 372
              G + T  +LDRE +  Y++ + A D G   R+   T              F+  +Y+
Sbjct: 310 KDKGEIVTKKKLDREERKLYEVPIMAMDSGG--RAGFTTVRVNVGDENDNPPVFLLREYK 367

Query: 373 VELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRG---RFSITSQNGRGLITVAQ 427
             +  +    T    + A D+D++    + Y I      G    F I    G G+     
Sbjct: 368 ALIQGNLTTNTTFFRVKAVDSDDNQNAVVKYSIFDSQNSGIKELFGIDENTG-GIYLRKS 426

Query: 428 PLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
            + + + + +   + A D G  S      + I I  +    PVFE       + E +  G
Sbjct: 427 AVRW-ENQLFQFFIRANDGGVPSLYTDVPIDIYIMSSAENPPVFEKKEKLLFLSESSLPG 485

Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
           T +     T   +  N    Y +   +S+E     + QF IN   G +   K LDRE   
Sbjct: 486 TVI-----TRLKLSGNVTAKYRI---LSDEL---EEPQFSIN-NVGELRLAKTLDRELKD 533

Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
            +L+ + A     P L+  TDV + V D NDN P+F+   Y+ ++ E+   G+S+ ++ A
Sbjct: 534 VHLIAILAETDSSPPLTAVTDVTLHVQDENDNTPMFESNPYSFSLAENIEKGSSIMKLTA 593

Query: 606 TDADVGLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            D+D G NG I Y L  +  +    F ID  +G I T   LD+E    +  + +A D G 
Sbjct: 594 RDSDSGSNGDIRYSLSTEVGDIVNIFDIDAYTGWITTLVPLDKEKREDYKFQVIATDNGQ 653

Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
           P  S+   V I+++D ND PP F+       +SE++  GT + +I   D D      + Y
Sbjct: 654 PKHSTRTTVIIRLKDYNDCPPTFKESHYKASVSEDALPGTVVLQIETTDKDVDLKTNIEY 713

Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILV 784
            I  GD  + F ++     +  E+  +  LD ES   +YEL +        +   + + V
Sbjct: 714 YIISGDPLSQFQIK-----NSGEVFVVKTLDRES-ISQYELGVIVTDGKFTSTANISVTV 767

Query: 785 TDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRI-LSGNNANLILLN 843
            D NDN P    ++      +   P     ++ A D D     + R  L+GN A    L+
Sbjct: 768 LDANDNPPYCLKYRYREQLSEGVHPGTYVLQIQANDIDEPANSRLRFYLTGNGAEDFNLD 827

Query: 844 ETTGSMTLSPQLN 856
           + +G +  + QL+
Sbjct: 828 KDSGQLKTARQLD 840



 Score =  218 bits (532), Expect = 2e-54
 Identities = 195/673 (28%), Positives = 295/673 (43%), Gaps = 34/673 (5%)

Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268
           + +V  LDYEQ +SY L+IRA D  S   S    + + ++DVND  P      +  +VSE
Sbjct: 2   IYVVDELDYEQRQSYELLIRATDSVS-GVSAEVPVSVLVQDVNDCPPEIEQDSYNITVSE 60

Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTM-TDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
               G +I++VQA D D G+N  +TY + TD   T        +DP  G +Y    LD E
Sbjct: 61  RAQFGTAILKVQAKDNDTGINQVVTYALQTDSKNTSEY---FHMDPTDGVIYLKKSLDHE 117

Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387
           T + +   V A+D G P  S+TA               F    Y   L+E    G  V  
Sbjct: 118 TLSHHHFTVIASDKGVPSLSSTAHVWVSVMDMNDNPPKFEQPSYTCVLSEHATRGQFVTV 177

Query: 388 LTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445
           ++A+D D  + +RL Y I  GN    + I   +  G+IT+    +F ++   +L VS TD
Sbjct: 178 VSASDPDYIDHDRLTYTIAQGNELQTYDINPVS--GIITLVNMQNFAEKHVTILNVSVTD 235

Query: 446 SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505
            G  +    V+I I  AN + P FE+  Y   V E+   G  V  V A D D G   ++T
Sbjct: 236 -GVYTSFTRVKITILPANLHNPTFEHLFYDVKVNENQLAGRLVTTVKAQDKDFGEFGRLT 294

Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTT 565
           Y +   IS+E      + F I+   G I T K LDRE    Y + + A D G    +  T
Sbjct: 295 YFI---ISDEI----QEYFSIDKDKGEIVTKKKLDREERKLYEVPIMAMDSG--GRAGFT 345

Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625
            V ++V D NDN PVF  + Y A I  +    T+  +V A D+D   N  + Y +     
Sbjct: 346 TVRVNVGDENDNPPVFLLREYKALIQGNLTTNTTFFRVKAVDSDDNQNAVVKYSIFDSQN 405

Query: 626 E--EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS 683
              +  F ID  +G I   K+  R           A DGG P   + V + I I    ++
Sbjct: 406 SGIKELFGIDENTGGIYLRKSAVRWENQLFQFFIRANDGGVPSLYTDVPIDIYIMSSAEN 465

Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD-DSNSFSLETRQG 742
           PPVFE      ++SE+S  GT I  ++        N    Y I   + +   FS+     
Sbjct: 466 PPVFEKKEKLLFLSESSLPGTVITRLKL-----SGNVTAKYRILSDELEEPQFSI---NN 517

Query: 743 SDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN 802
             +  L   +D + +       L    +SPPL     V + V D NDN P+ +     F+
Sbjct: 518 VGELRLAKTLDRELKDVHLIAILAETDSSPPLTAVTDVTLHVQDENDNTPMFESNPYSFS 577

Query: 803 NYKDCFPVGPFGRVPAYDAD--VTDKLQYRILS--GNNANLILLNETTGSMTLSPQLNTN 858
             ++        ++ A D+D      ++Y + +  G+  N+  ++  TG +T    L+  
Sbjct: 578 LAENIEKGSSIMKLTARDSDSGSNGDIRYSLSTEVGDIVNIFDIDAYTGWITTLVPLDKE 637

Query: 859 VPKLATMEVSVTD 871
             +    +V  TD
Sbjct: 638 KREDYKFQVIATD 650



 Score = 83.0 bits (196), Expect = 1e-13
 Identities = 70/236 (29%), Positives = 106/236 (44%), Gaps = 13/236 (5%)

Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
           LD E   +++L   A D      S+ V V + ++D+ND PP  E D     +SE +  GT
Sbjct: 8   LDYEQRQSYELLIRATDS-VSGVSAEVPVSVLVQDVNDCPPEIEQDSYNITVSERAQFGT 66

Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764
            I +++A D D G N VV Y+++   DS + S           +     LD+E+    + 
Sbjct: 67  AILKVQAKDNDTGINQVVTYALQ--TDSKNTSEYFHMDPTDGVIYLKKSLDHETLSHHHF 124

Query: 765 LVIRAAS--PPLWNDVRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRV-PAY 819
            VI +    P L +   V + V D+NDN P  +   +  + + +      G F  V  A 
Sbjct: 125 TVIASDKGVPSLSSTAHVWVSVMDMNDNPPKFEQPSYTCVLSEHATR---GQFVTVVSAS 181

Query: 820 DADVTD--KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGV 873
           D D  D  +L Y I  GN      +N  +G +TL    N     +  + VSVTDGV
Sbjct: 182 DPDYIDHDRLTYTIAQGNELQTYDINPVSGIITLVNMQNFAEKHVTILNVSVTDGV 237



 Score = 40.7 bits (91), Expect = 0.57
 Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 10/75 (13%)

Query: 1511 CQSRADCMLSICPPYSKCVTSWDSST------CTCEAGRVGPQC---VSACELGPC-GAA 1560
            C+ +      I  P S  VTS+ S+       C+C+ G  G +C   V+ C   PC    
Sbjct: 1524 CEDKLVLDPKIVNPISTDVTSFVSARHVHKMECSCKEGYGGDKCQHAVNECSKSPCPNYK 1583

Query: 1561 RCVPDQTPKGYSCAC 1575
             C+PD + +GY C C
Sbjct: 1584 NCIPDSSDQGYHCIC 1598


>UniRef50_Q4SDW5 Cluster: Chromosome undetermined SCAF14629, whole
            genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
            Chromosome undetermined SCAF14629, whole genome shotgun
            sequence - Tetraodon nigroviridis (Green puffer)
          Length = 1957

 Score =  479 bits (1181), Expect = e-133
 Identities = 249/691 (36%), Positives = 368/691 (53%), Gaps = 65/691 (9%)

Query: 1256 LDLTGPLQIGGLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRS 1315
            LDLTGPL +GG+PN+P  F V N+DFVGC+    ID K ID++S++A+NGT  GC  K++
Sbjct: 457  LDLTGPLLLGGVPNLPEDFPVSNRDFVGCMKKLSIDSKPIDMDSHIANNGTTPGCSAKKN 516

Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLRPIQL 1375
             C    C+NG  C   W+TYICDC  G+ GK+C      P  F G  ++S++     + +
Sbjct: 517  FCVKQVCHNGGVCVSKWNTYICDCPTGYGGKNCEQVMPSPQFFNGQALVSWSDPDITVAV 576

Query: 1376 PWLNALSIRTRQRDAFVMSI---------------QLKSGLLHYSYNGETMYLPMATLSD 1420
            PW   L  RTRQ    +M                 QL+  ++       T+  P   + D
Sbjct: 577  PWYMGLMFRTRQPAGTLMQANAGLSSTINLMVSEQQLRMEVMSRHQLVATLGFPQVRVDD 636

Query: 1421 GAWHR--IEIKWL--GTDI----SVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTA 1472
            G WH   +E++ +  G DI    +V++DY +    +  +   + G  +  + +GGL    
Sbjct: 637  GEWHHLLVELRSVKEGKDIKYMAAVSLDYDMYQKSVE-IGYDLPGLKLQTLYVGGLPAAD 695

Query: 1473 GLLASDVGFFEGCIQDVRIG-TAQSLLN---RPTVRENVRDGCQSRADCMLSICPPYSKC 1528
              ++     F GCIQ VR+G T+ ++ N      ++  V+DGC     C  + CP  S C
Sbjct: 696  NHVSKG---FVGCIQGVRMGETSTNVANVNMAQGLKIRVKDGCDVADPCDSNTCPENSHC 752

Query: 1529 VTSWDSSTCTCEAGRV--------------------------GPQCVSACELGPCG-AAR 1561
               W + TC C+ G +                          G +C  AC+L PC   + 
Sbjct: 753  SDDWSTHTCVCDPGNMHVHKPLSSSLKLLHITSCPLFPTGYFGKECTDACQLNPCEHVST 812

Query: 1562 CV-PDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCN 1620
            CV    +  GY+C C   Y      C    ++ CP GWWG   CGPC+CD +RG+H  CN
Sbjct: 813  CVRKPSSSHGYTCECGQNYY--GQYCENKVEKPCPHGWWGSPMCGPCSCDTSRGFHKDCN 870

Query: 1621 KENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANA 1680
            K +G+C CK+NHY+PEG   C PC+C++ GSE+ +C+A TGQC C+ GVIGR C+ C N 
Sbjct: 871  KTSGECRCKDNHYRPEGEDVCYPCECFSLGSESRTCDAVTGQCPCKGGVIGRQCNRCDNP 930

Query: 1681 YAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSGRATRTCDETKDVPW 1740
            +AEVT ++GCEVVY+GCP++F  G+WWP+T+FG    T CP GS G A R C + K   W
Sbjct: 931  FAEVT-STGCEVVYEGCPKAFDAGIWWPKTRFGRPAATQCPKGSVGTAIRHCSDEKG--W 987

Query: 1741 QDPDMFNCTTATFYQLRKQLHKIETGELTMNTFVGVRVAADLSTACANTPRLYGADVVVA 1800
               D+FNCTT TF  L+K   ++      M++         L +A  N P  +G DV  A
Sbjct: 988  LQADLFNCTTVTFTHLKKMNDELRRNISRMDSEHSKAAVRLLHSATTNMPHYFGNDVRTA 1047

Query: 1801 EGILLELMDYELRQAGLNLTHSQDKDYVRNLLKSTNTILNVEYEREWKRIRELTGHGAEL 1860
              +L  ++ YE +QAG  LT  +D ++  NL+++ +++L+   +  W +I+   G  A L
Sbjct: 1048 AELLNHVLQYESQQAGFELTAMKDSEFNENLVRAGSSLLDPSNKEHWDQIQRTEGGTAHL 1107

Query: 1861 LVQKFDEYIAVLAESQHDTYTSPFEIVTKDV 1891
            L + F++Y   LA++   TY  PF IVT ++
Sbjct: 1108 L-RNFEDYANTLAQNVRKTYLKPFTIVTDNM 1137



 Score =  213 bits (520), Expect = 6e-53
 Identities = 105/244 (43%), Positives = 162/244 (66%), Gaps = 16/244 (6%)

Query: 867  VSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPC 926
            + +TDG++ +  +  L V +IT++ML NSITVRL +M+ E+FLSPLL  F++G+AA++  
Sbjct: 14   IELTDGLHHVTVVCTLRVTIITDDMLTNSITVRLENMSQERFLSPLLSLFLEGVAAVLST 73

Query: 927  PKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTL 986
             +E +++F++Q+DTDV G+ILNV+FSA +P    G        +    L+E++YL+RT L
Sbjct: 74   RREGVFLFNIQNDTDVQGSILNVTFSAMQPGGSQG----KGTFFPSEELQEQIYLNRTLL 129

Query: 987  ARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQC 1046
              +++ +VLPFDDNIC+ EPC N+ +C++VLKF ++  F++S++VLFRPI+P+    C+C
Sbjct: 130  RLISSQEVLPFDDNICLREPCENYMKCVSVLKFDSSPPFISSETVLFRPIHPINGLRCRC 189

Query: 1047 PEGFTGVNCETILTKASCEVD-GDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCEL 1105
            P GFTG  CET       E+D      C++  +C   REGG  C+ C  D  +T   CE+
Sbjct: 190  PLGFTGDYCET-------EIDLCYSGPCKNNGRC-RSREGGYTCE-CMDD--FTGENCEV 238

Query: 1106 RARS 1109
             A S
Sbjct: 239  NASS 242



 Score =  131 bits (317), Expect = 2e-28
 Identities = 63/174 (36%), Positives = 103/174 (59%), Gaps = 16/174 (9%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            +TC+C + FTG NCE   +   C + G   +C++G  CV R  GG +C+ C     Y   
Sbjct: 223  YTCECMDDFTGENCEVNASSGRC-IPG---VCKNGGVCVNRLAGGFMCE-CP-PGEYEKP 276

Query: 1102 VCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVS 1161
             CE+  RSFP  SF+TF GL++R    +   FAT+  + LLLYNGR+N++HDF+A+E++ 
Sbjct: 277  YCEMTTRSFPGQSFITFRGLRQRFHFTVSFMFATRERNALLLYNGRFNQKHDFIAVEIID 336

Query: 1162 SEAGRGGGPGLRFSFSLGGGKSEIT--VEGNVGDGSWHTVEIEYFNRTITMILD 1213
             +        ++ +FS G  ++ ++  V G V DG WH++++ Y+N+    ++D
Sbjct: 337  EQ--------IQLTFSGGETRTTVSPYVPGGVSDGQWHSIQLHYYNKEGGSLVD 382



 Score = 69.3 bits (162), Expect = 1e-09
 Identities = 43/128 (33%), Positives = 71/128 (55%), Gaps = 14/128 (10%)

Query: 2196 RTNPQCVHWS---TLRGSGEWSRVGCHTEIDYDWSPYSEEPLLINCTCNHLSTFAVLVDE 2252
            RT P CV W+    + G+G WS  GC           +     I+C CNH+++FAVL+D 
Sbjct: 1315 RTKPVCVFWNHSLAVGGTGGWSSKGCEL--------LNRNNSHISCQCNHMTSFAVLMDI 1366

Query: 2253 VDVEFIPEPSLLESVTSYTAFSISLPLLLTSWAALCLIRGGAATVSNSIHKHLIFSVFMA 2312
               E      L   + +YT  S+SL LLL +   LCL+R   + + ++IH++L+ ++F +
Sbjct: 1367 SKREH--GDVLPLKIVTYTTVSVSLFLLLITLILLCLLRRLRSNL-HAIHRNLVAALFFS 1423

Query: 2313 ELLYLIAL 2320
            EL++L+ +
Sbjct: 1424 ELVFLLGI 1431



 Score = 36.7 bits (81), Expect = 9.2
 Identities = 13/39 (33%), Positives = 18/39 (46%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C  +   C S PC N   C      Y C+C +  TG++C
Sbjct: 198  CETEIDLCYSGPCKNNGRCRSREGGYTCECMDDFTGENC 236


>UniRef50_UPI0000E473B7 Cluster: PREDICTED: similar to KIAA0279
            protein; n=1; Strongylocentrotus purpuratus|Rep:
            PREDICTED: similar to KIAA0279 protein -
            Strongylocentrotus purpuratus
          Length = 1428

 Score =  475 bits (1171), Expect = e-132
 Identities = 263/749 (35%), Positives = 385/749 (51%), Gaps = 52/749 (6%)

Query: 1204 FNRTITMILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQ 1263
            F  T  +ILDDCD  ++L     F   + CA        A  +   E   RFLDL GP  
Sbjct: 10   FMITARIILDDCDPAVALDNGHQFD-DFTCA--------AETQFLGEL--RFLDLNGPFI 58

Query: 1264 IGGLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCY 1323
            IGGLP +PS F V+N DF GC+ D YI+++ +DL + V D  T  GCP K + C S PC+
Sbjct: 59   IGGLPELPSEFPVENTDFDGCLRDIYINNELLDLATNVEDYNTEPGCPHKANFCESDPCH 118

Query: 1324 NGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLRPIQLPWLNALSI 1383
             G  C + WD Y C C  G  G +C ++   P RF G+  + F+ L   + LPW N +  
Sbjct: 119  TGGSCENGWDRYHCHCSSGSGGVNCQEALSTPIRFIGESYMRFD-LTHTVSLPWTNRVVF 177

Query: 1384 RTRQRDAFVMSIQLKS----------GLLHYSYNGETMYLPMATLSDGAWHRIEIKWLGT 1433
            RT Q +  +M IQL +          G LHY  +   + L   T +D  WH I+ +W   
Sbjct: 178  RTGQPNGVLMFIQLSNNINIRIELVEGHLHYVTSSVDVQLDQVTFNDREWHDIKAEWKND 237

Query: 1434 DISVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGLLASDVGFFEGCIQDVRIGT 1493
             I ++ D+  +        + I G+ + ++ +GG  T  G+  +    F GC+Q + IG 
Sbjct: 238  KIKLSSDFD-KYKTSVRATDAINGKTVERVDLGGRLTDNGMYNA----FTGCMQGMSIG- 291

Query: 1494 AQSLLNRPTVR-ENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSAC 1552
             +  L+  TV   N+ +GC     C  + CP +S CV  WD++ C C  G VGP CVSAC
Sbjct: 292  -ERPLDPSTVEGVNIEEGCNVPRACETAKCPIHSVCVDLWDANECQCNKGYVGPDCVSAC 350

Query: 1553 ELGPC-GAARCVPDQTPK-GYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACD 1610
            +L  C   + C  D + + GY+C+C   Y      C E+   EC   WWG   CGPC CD
Sbjct: 351  DLRVCEHGSSCTLDSSSEFGYTCSCSDLY--YGDHC-ENIINECADDWWGHQICGPCECD 407

Query: 1611 VTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVI 1670
               G+   CNK   +C+C E+ Y+P  +  C PC CY  GS    C   TG C C+ G I
Sbjct: 408  EEMGFESACNKTTSECYCAEHSYRPSDSDTCFPCNCYEIGSLGQDCNQETGACTCKRGAI 467

Query: 1671 GRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSGRATR 1730
            GR CD C + +AEVT   GCEVVYD CP+ FA  +WWPRTKFG     DCP  S G ATR
Sbjct: 468  GRRCDECVDPHAEVTLR-GCEVVYDSCPKRFAEALWWPRTKFGKTATLDCPGESYGFATR 526

Query: 1731 TCDETKDVPWQDPDMFNCTTATFYQLRKQLHKIETGELTMNTFVGVRVAADLSTACANTP 1790
             CD   +  WQ P +FNCT+  F +L+  L  ++ G+  +   V   +A  L  A   T 
Sbjct: 527  YCD--IETNWQTPSLFNCTSDNFLRLQNILQTLQNGQ-KLYPEVSFNIAMQLQEATNETD 583

Query: 1791 RLYGADVVVAEGILLELMDYELRQAGLNLTHSQDKDYVRNLLKSTNTILNVEYEREWKRI 1850
              +G D+ +A  +L  L+ +E +Q GLN+T +  K + +N++++ + +   +    W+ I
Sbjct: 584  LFHGNDINIAYQVLGYLLRHESKQVGLNVTATIMKSFTKNIVETVSRLFEPQNRIHWEMI 643

Query: 1851 RELTGHGAELL--VQKFDEYIAVLAESQHDTYTSPFEIVTKDVVISVDTVTSESIYGFEP 1908
            ++ +   AE++  ++KF   IA    S   +YT  F I+T ++++  D +  ++      
Sbjct: 644  QQTSRGTAEIMEDMEKFALNIAKFTNS--FSYTPEFSIITPNIIMHHDIILRDN------ 695

Query: 1909 TQLNRLNVDSYTTERVVALPDTSAFIHSP 1937
               +   V  Y  E +++L D S  +H P
Sbjct: 696  --FSMRAVPEYEMETLLSLEDNSQ-VHIP 721



 Score = 67.3 bits (157), Expect = 6e-09
 Identities = 44/165 (26%), Positives = 77/165 (46%), Gaps = 11/165 (6%)

Query: 2163 VGKKMYRSLSGIRLKKPIRLQIWLDINRETFGSRTNPQCVHWSTL--RGSGEWSRVGCHT 2220
            V   +Y  L+   L  P+   + ++       +R+ PQCV+W      G+G WS  GC  
Sbjct: 782  VSFSIYDELANGTLPDPLLTPVIVEFQSIDAVNRSGPQCVYWDFEFNNGTGGWSTYGC-- 839

Query: 2221 EIDYDWSPYSEEPLLINCTCNHLSTFAVLVDEVDVEFIPEPSLLESVTSYTAFSISLPLL 2280
                + S Y+     INC+C+HL+  AV++D     ++ E  +  S+  Y    I++  L
Sbjct: 840  ----ELSGYNRTH--INCSCSHLTNIAVIMDNAPYMYVEEVMITLSIAVYIGVGIAILCL 893

Query: 2281 LTSWAALCLIRGGAATVSNSIHKHLIFSVFMAELLYLIALKARTS 2325
            L ++  L  +     T  NSIH +L F +  AE+ + + +    +
Sbjct: 894  LITFLTLLGV-SNLHTNLNSIHINLCFVLIAAEVTFGVGISTENN 937


>UniRef50_Q8MY78 Cluster: Ap-cadherin; n=1; Patiria pectinifera|Rep:
            Ap-cadherin - Asterina pectinifera (Starfish)
          Length = 2909

 Score =  472 bits (1164), Expect = e-131
 Identities = 451/1653 (27%), Positives = 703/1653 (42%), Gaps = 175/1653 (10%)

Query: 9    QQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAE-VEYTIELVTA 67
            Q++NV D ND +P F +  +  +  E   +   V  ++A D D     + + Y+++   +
Sbjct: 1150 QRVNVQDVNDETPQFPVTNFFVAFPEDVDAPFLVTRVQAEDADTETAFKTITYSLDQTFS 1209

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
            D                     FRID  +G L +    DRE    Y+V V ATD A    
Sbjct: 1210 DA------------------QYFRIDPTTGDLTSTIKFDRESEDSYSVQVIATDGAPSSL 1251

Query: 128  DRLSST----ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183
                        + +N++D NDN P F    YT ++ ED  V     + ++ ATD D   
Sbjct: 1252 PSAGGPNKGYLRVVINVVDKNDNPPVFDRPMYTRTIREDEPVGYE--VIQVTATDVD--P 1307

Query: 184  NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
            +S  RY I   NT   F +D  +G +S+   LDYE  R Y L+  A DG + +   +T +
Sbjct: 1308 DSIPRYLITANNTGGAFEVDPATGAISIASPLDYETQREYWLMYSANDGLNVA---STVI 1364

Query: 244  LINIRDVNDNAPRFYTSLFQESVSENVP-IGYSIVRVQAYDAD-EGVNAELTYTMTDKDY 301
             I + +VND  P F   ++   VSEN P +   +++V A D D + V A++ Y++   + 
Sbjct: 1365 RIQLENVNDEKPEFELPVYTAEVSENDPNVPRQLLQVTAVDGDADAVQADIRYSL---EG 1421

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
            TG      TID  +G +  +  LDRE+ + ++LLV ATDGG    S T            
Sbjct: 1422 TG-AGTTFTIDAVTGQITLTEMLDRESVSIWKLLVKATDGGGTGTSLTGYADLEVTVLDE 1480

Query: 362  XXXX-FMPG-QYEVELAEDEPPGTPVVTLTATDADEDN---RLHYEITGGNT-----RGR 411
                 F P  +Y   + E+ P GTPV+ +TA D D+ N   R+ Y     +       G 
Sbjct: 1481 NDNSPFFPELEYRGSVPENSPGGTPVMQVTAIDYDDPNQFGRITYSTISSSEIPNDGSGL 1540

Query: 412  FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN 471
            F I    G   +     LD ++   Y L + A+D           I I D N+ APVF  
Sbjct: 1541 FQIDGSTGWVTVKSGAVLDREKNDTYTLRIRASDVPNSEALTDAIIQILDVNDNAPVFVG 1600

Query: 472  APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT- 530
             PY  SV E  P+G TV  VS TD+DV  N ++ + +     N   +    + V +P T 
Sbjct: 1601 GPYATSVEETQPVGATVWEVSVTDADVDFNEEVQFGIIG--GNVGGSF---EIVADPLTL 1655

Query: 531  -GAITTNKLLDRETMSG-YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY-T 587
             G I   + LD E+ +  Y LT+T  D   P     T + I V+DVND  P F    Y +
Sbjct: 1656 IGIIRIARPLDYESPNKLYTLTITVDDNSGPGSQSQTTITIDVLDVNDVAPTFNPAEYVS 1715

Query: 588  ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV-------IR 640
            AN++E   VGTS+  V A+D + G+ G+  + +DP    +G F I+  S +       ++
Sbjct: 1716 ANVLESVDVGTSIGTVSASDPEAGVFGQFTFSIDPASDPDGLFSIEEISPIGAVRRADVK 1775

Query: 641  TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700
            T K LDRE+V TH L   A D G PP +    +++ ++D+ND+PP F +D     I EN 
Sbjct: 1776 TAKPLDRENVETHVLTLRATDLGVPPLTGYATLNLTLDDVNDTPPTFATDYRP-TIKENL 1834

Query: 701  PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS---LETRQGSDKAELVTMVDLDYE 757
                 +G I A D D          ++   D++SF+   +    G++ +     +  D E
Sbjct: 1835 AEVQFVGYISAKDEDPTGGPPFTLVVEPNTDTDSFTWFDVGGTTGNNLSISSKAISFDRE 1894

Query: 758  SPRKKYELVIRAASPPLWNDVRVEILVTDV---NDNAPVMKDFQIIFNNYKDCFPVGPFG 814
            + +  Y + IR        +  V  L+ ++   NDN       +++  +++   P  P G
Sbjct: 1895 T-QATYSIPIRITDRAPNGNSGVNYLIVEIEDENDNPHFGTTKEMLVYSFEGNIPDSPIG 1953

Query: 815  RVPAYDAD-VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-G 872
             V   D D + DK  Y  LS        ++E TG +T+   L          +V V+D G
Sbjct: 1954 YVGVDDKDTLEDKTYYPELSDVYKQYFRVDEDTGQVTI---LAGTPAGTYEFDVRVSDGG 2010

Query: 873  VN-EIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLG------FFIDG-LAAII 924
            V+ +  + + + VR I EE + +S + R   +TAE+ +S   G        + G LA II
Sbjct: 2011 VHADQTSTVIVDVRDIPEEAVRSSGSFRFEGVTAEELISVPSGGGQTKLDILKGILAEII 2070

Query: 925  PCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRT 984
            P   EN+ IFSV          +NV       D      G  SP+Y P  +      +R 
Sbjct: 2071 PAKPENVDIFSV----------INVPNQPTTVDVRYSAHG--SPYYPPEQMDGAALANRD 2118

Query: 985  TLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTC 1044
             +A+   V +     ++C+ E       C  VL+       +N+ S  F  +   T   C
Sbjct: 2119 RIAQALGVTIGMIKIDMCLLESACE-SACTNVLEIDPQPTVINTPSASFTAVTTSTVAKC 2177

Query: 1045 QCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCE 1104
             C     G N +       C+ D     C +G  C   + GG  CQ C     Y    C+
Sbjct: 2178 VC-----GANTQ---QPGLCDFDA----CLNGGTCTETQGGGHTCQ-C--PTGYDGPDCQ 2222

Query: 1105 LRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRY-----NERHDFLALEL 1159
               R F    F  F  L++    H  L+F T    G+LLYNG       +   DF+ ++L
Sbjct: 2223 QTTREFK-DGFAHFGTLQQCEETHTSLEFITTAAEGVLLYNGPMIPVTGDMPEDFMLIQL 2281

Query: 1160 VSSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKVL 1219
            +      GG P L  +   G     +    N+GDG WH +++    + +  +LD C    
Sbjct: 2282 L------GGQPVLEINLGSGTLSLSLPATTNLGDGKWHRLDVYRNGKDVEFMLDRC---- 2331

Query: 1220 SLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNK 1279
                  D  +  A  + +R+    +        ++FL++  PLQ+GG+            
Sbjct: 2332 -----KDAAVAEASTSSSRQTDQCKITGQAPGDNKFLNVNTPLQLGGIDKSAGFTYPDGI 2386

Query: 1280 DFV----GCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTY 1335
             F     GC+ +   D    DL +     G+ AGC    S+     C NG  C   + TY
Sbjct: 2387 TFAASYDGCMKNLEQDSTLYDLETPGKAVGSEAGC----SKLVCGECNNGT-CEGDFSTY 2441

Query: 1336 ICDCKEGHTGKDCADSTGPPWRFGGDGMLSF--NPLLRPIQLPWLNALSIRTRQRDAFVM 1393
             C C  G+TG+ C D T P + F  +  + +   P +          +S RTR+ +  + 
Sbjct: 2442 TCLCDPGYTGEKC-DQTTPAYDFATESYVRYQLKPTIVIDSREGNYQVSFRTREDEGLLW 2500

Query: 1394 SI-----------QLKSGLLHYSYN---GE-TMYLPMATLSDGAWHRIEIKWLGTDISVT 1438
            +I           +L +G +   +N   GE +MYL    ++DG WH + ++     I+V 
Sbjct: 2501 TITNLNGLEFTTLELINGYIRSRWNLGDGEHSMYLDQYAVNDGDWHMVHLERFDFYITVR 2560

Query: 1439 VDYGLRTVLMPMLANKIQGQYI--GKILIGGLDTTAGLLASDVGFFEGCIQDVRIGT--- 1493
            +D G     M    +      +    +L+G        ++ D   F+GC+ D RI     
Sbjct: 2561 IDGGGGVRQMESRESTFSTLEVDPNSLLLGAFVVHVVDISQD---FQGCMNDPRINNYYL 2617

Query: 1494 ---AQSLLNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAG--RVGPQC 1548
                +S    P    +V +GC S   C  + CP    C   W    C C+ G   +G  C
Sbjct: 2618 GFETESDYAIPQPTASVTEGCPSYDPCASNPCPVPFICKDVWRKYICICKPGFEELGNTC 2677

Query: 1549 VSA--CELGPCGAARCVPDQTPKGYSCACEPGY 1579
            V+   C+  PC       D+   G+ C C  GY
Sbjct: 2678 VAIDDCDPNPCLNGGICTDR-DSGFECECPDGY 2709



 Score =  205 bits (501), Expect = 1e-50
 Identities = 235/887 (26%), Positives = 371/887 (41%), Gaps = 78/887 (8%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYE-ASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELV 65
            +   + V D ND  P FE + Y   +V E   + T + T+ ATD D   N  + Y+  L+
Sbjct: 631  VRVNVEVTDINDCVPKFERETYSFRNVIETIDTTTPIGTVAATDCDADPNNILTYS--LI 688

Query: 66   TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKV-ARYTVLVKATDQAS 124
             A                    D FR+D + G L     LD +     Y +  +  DQA 
Sbjct: 689  GAQA------------------DKFRLDSQ-GVLYAATELDYDVGDGSYELEAQVRDQAG 729

Query: 125  PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS-VDEDISVTDNPVIAKIKATDADVGA 183
                  + TAT+ V + D ND  P F     +V  +DED  +    +I  + A+DAD   
Sbjct: 730  G-----ADTATVWVYLTDVNDEGPVFLNTDGSVYYIDEDAPL--GYIIGTVYASDAD--K 780

Query: 184  NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
               I + I G +T   F ID  +G +S + T +  +  SYR  + A DG     ++  ++
Sbjct: 781  TDTITFGIQGSST---FQIDPQTGVISRIGTGNLPEA-SYRFNVTATDG---KYTSDAEV 833

Query: 244  LINIRDVNDNAPRFYT-SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
             I + D+NDN P F   + +  S+SE+  IG  +++VQA DAD+GVNAE+ Y     D  
Sbjct: 834  EIQVNDINDNTPIFPDCNSYAPSISESAAIGTFLIKVQATDADKGVNAEIAY-----DIA 888

Query: 303  GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD--GGDPPRSATATXXXXXXXXX 360
            G+ + P TID  +G + T   LDRET     ++VTA D  G                   
Sbjct: 889  GS-NNPFTIDAVTGDISTQDPLDRETTPTIDIVVTAQDNPGSIFSNQGFCIITVNITDVN 947

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420
                 F    Y V ++   P   P++ +   DAD      +  T G T     +   N  
Sbjct: 948  DNRPTFPLEDYVVIISNTAPQFAPILKVEVEDADLPTPAGF--TYGLTTQNPVLFEINQN 1005

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDAN-NYAPVFENAPYTASVF 479
            G I     L    +  +   V A D   R+  + VQ+ +     +  P + +     +V 
Sbjct: 1006 GEIFPVADLSVYDDNTFNFKVEAEDGPNRA-KSNVQVKVLATGVDQPPEWVSTFPDITVM 1064

Query: 480  EDAPIGTTVLVVSA-TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
            E+  I   +  + A + S  G+  ++      + ++E       Q V +     +  +  
Sbjct: 1065 ENISINDVIGTLQAQSRSGNGVGYRVVQGQIPQTNSE--GQFAVQNVGDSMIANLYISAP 1122

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            LD ET   Y L V A D G   LS      ++V DVND  P F    +     ED     
Sbjct: 1123 LDYETTKFYTLQVEAYDDG-NRLSILGTQRVNVQDVNDETPQFPVTNFFVAFPEDVDAPF 1181

Query: 599  SVSQVGATDADVGLNGR-IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
             V++V A DAD     + I Y LD    +   F IDP +G + +    DRES  ++ ++ 
Sbjct: 1182 LVTRVQAEDADTETAFKTITYSLDQTFSDAQYFRIDPTTGDLTSTIKFDRESEDSYSVQV 1241

Query: 658  VAIDGGTP-------PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710
            +A DG          P    + V I + D ND+PPVF+    T  I E+ P+G  + ++ 
Sbjct: 1242 IATDGAPSSLPSAGGPNKGYLRVVINVVDKNDNPPVFDRPMYTRTIREDEPVGYEVIQVT 1301

Query: 711  AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770
            A D D  P+++  Y I   +   +F ++   G+    +     LDYE+ R +Y L+  A 
Sbjct: 1302 ATDVD--PDSIPRYLITANNTGGAFEVDPATGA----ISIASPLDYETQR-EYWLMYSAN 1354

Query: 771  SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP--FGRVPAYDAD---VTD 825
                     + I + +VND  P   +  +      +  P  P    +V A D D   V  
Sbjct: 1355 DGLNVASTVIRIQLENVNDEKPEF-ELPVYTAEVSENDPNVPRQLLQVTAVDGDADAVQA 1413

Query: 826  KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
             ++Y +          ++  TG +TL+  L+     +  + V  TDG
Sbjct: 1414 DIRYSLEGTGAGTTFTIDAVTGQITLTEMLDRESVSIWKLLVKATDG 1460



 Score =  187 bits (455), Expect = 4e-45
 Identities = 220/808 (27%), Positives = 346/808 (42%), Gaps = 72/808 (8%)

Query: 89   VFRIDGRSGALLTRASLDR--EKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146
            +F +D  SG + T  S  +  ++  +Y + V A D+         S+    VNI   + +
Sbjct: 487  LFTVDEESGWIKTSLSEGQGYQQGQKYILSVYAQDENG-------SSIPAEVNIFGGS-H 538

Query: 147  YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQM---QFSID 203
             PQF+++ Y V+V E++    N +       DA   +N A+ +A++   T     + SID
Sbjct: 539  PPQFTQEVYNVAVTEEVIGEQNVI-----DIDAFSFSNVAVTFALLNSETNQPIPRHSID 593

Query: 204  SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263
              SG + L++ +D E + SY L ++A +      S T ++ + + D+ND  P+F    + 
Sbjct: 594  PSSGQIKLLEKVDREVLDSYFLEVQATEDVQDGLSTTVRVNVEVTDINDCVPKFERETYS 653

Query: 264  -ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322
              +V E +     I  V A D D   N  LTY++      G       +D + G +Y + 
Sbjct: 654  FRNVIETIDTTTPIGTVAATDCDADPNNILTYSL-----IGAQADKFRLDSQ-GVLYAAT 707

Query: 323  QLDRET-QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ-YEVELAEDEP 380
            +LD +     Y+L     D      +AT                   G  Y ++  ED P
Sbjct: 708  ELDYDVGDGSYELEAQVRDQAGGADTATVWVYLTDVNDEGPVFLNTDGSVYYID--EDAP 765

Query: 381  PGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440
             G  + T+ A+DAD+ + + + I G +T   F I  Q G   +          E  Y   
Sbjct: 766  LGYIIGTVYASDADKTDTITFGIQGSST---FQIDPQTG---VISRIGTGNLPEASYRFN 819

Query: 441  VSATDSGGRSDTAMVQINITDANNYAPVFENA-PYTASVFEDAPIGTTVLVVSATDSDVG 499
            V+ATD    SD A V+I + D N+  P+F +   Y  S+ E A IGT ++ V ATD+D G
Sbjct: 820  VTATDGKYTSD-AEVEIQVNDINDNTPIFPDCNSYAPSISESAAIGTFLIKVQATDADKG 878

Query: 500  INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD--GG 557
            +NA+I Y          +A  +  F I+  TG I+T   LDRET     + VTA+D  G 
Sbjct: 879  VNAEIAYD---------IAGSNNPFTIDAVTGDISTQDPLDRETTPTIDIVVTAQDNPGS 929

Query: 558  VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617
            + S      + +++ DVNDN P F  + Y   I   A     + +V   DAD+       
Sbjct: 930  IFSNQGFCIITVNITDVNDNRPTFPLEDYVVIISNTAPQFAPILKVEVEDADLPTPAGFT 989

Query: 618  YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
            Y L  ++     F I+  +G I     L      T + K  A DG    +S+ V V +  
Sbjct: 990  YGLTTQN--PVLFEIN-QNGEIFPVADLSVYDDNTFNFKVEAEDGPNRAKSN-VQVKVLA 1045

Query: 678  EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD-PDEGPN-AVVHYSIKGGDDSNSF 735
              + D PP + S      + EN  I   IG ++A      G    VV   I   +    F
Sbjct: 1046 TGV-DQPPEWVSTFPDITVMENISINDVIGTLQAQSRSGNGVGYRVVQGQIPQTNSEGQF 1104

Query: 736  SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDV--RVEILVTDVNDNAPV 793
            +++    S  A L     LDYE+  K Y L + A        +     + V DVND  P 
Sbjct: 1105 AVQNVGDSMIANLYISAPLDYET-TKFYTLQVEAYDDGNRLSILGTQRVNVQDVNDETP- 1162

Query: 794  MKDFQIIFNNYKDCFPV---GPF--GRVPAYDADVT---DKLQYRI-LSGNNANLILLNE 844
                Q    N+   FP     PF   RV A DAD       + Y +  + ++A    ++ 
Sbjct: 1163 ----QFPVTNFFVAFPEDVDAPFLVTRVQAEDADTETAFKTITYSLDQTFSDAQYFRIDP 1218

Query: 845  TTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            TTG +T + + +       +++V  TDG
Sbjct: 1219 TTGDLTSTIKFDRESEDSYSVQVIATDG 1246



 Score =  177 bits (431), Expect = 4e-42
 Identities = 230/904 (25%), Positives = 397/904 (43%), Gaps = 119/904 (13%)

Query: 19   HSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXX 78
            H PVF    +  S+ E +  GT   T+ ATD+D+G+N  V Y +                
Sbjct: 221  HPPVFAFSSFIYSIAENSPVGTIAGTVFATDEDMGENGRVTYHL---------------- 264

Query: 79   XXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHV 138
                   +   F +   SG +      +   V  YT+ V A D  +P  +  S+   + +
Sbjct: 265  -----LKLNRYFTVGQESGLVTVT---EPTPVGEYTMQVVARDAGTPFQE--SAPVPLQI 314

Query: 139  NIIDDNDNY----------PQFS-EKTYTVSV--DEDISVTDNPVIAKIKATDADVGANS 185
            ++I  + N           P +   K +   V  +E + V ++  I  +  T + +  N 
Sbjct: 315  SVISSSSNMIPYGNDMMFAPDYKPSKRFRREVLPEERVPVNEDTAINTVIFTVSSL--ND 372

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
              R+A +G    + F ++  +G+V L+  L++EQ   +   +   +  +  + +T +++I
Sbjct: 373  TDRFAYVGTPNPL-FGLNETTGEVKLLDQLNFEQATVHEFEVEITNVENTDKRDTQRIII 431

Query: 246  NIRDVNDNAPRFYTSLFQ--ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
             +++VN+  P++   ++   E V  + P G SI  ++A D +    +++ + +     +G
Sbjct: 432  EVQNVNE-PPQWEIGVYPYIEVVPVDAPTGASIFHLRASDPE---GSDVRFYLN----SG 483

Query: 304  NVDLPITIDPRSGWVYTS---GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
               L  T+D  SGW+ TS   GQ  ++ Q KY L V A D      + ++          
Sbjct: 484  GSGL-FTVDEESGWIKTSLSEGQGYQQGQ-KYILSVYAQD-----ENGSSIPAEVNIFGG 536

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTR---GRFSITSQ 417
                 F    Y V + E+      V+ + A  +  +  + + +    T     R SI   
Sbjct: 537  SHPPQFTQEVYNVAVTEEVIGEQNVIDIDAF-SFSNVAVTFALLNSETNQPIPRHSIDPS 595

Query: 418  NGRGLITVAQPLDFKQERRYVLTVSATD--SGGRSDTAMVQINITDANNYAPVFENAPYT 475
            +G+  I + + +D +    Y L V AT+    G S T  V + +TD N+  P FE   Y+
Sbjct: 596  SGQ--IKLLEKVDREVLDSYFLEVQATEDVQDGLSTTVRVNVEVTDINDCVPKFERETYS 653

Query: 476  -ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
              +V E     T +  V+ATD D   N  +TYSL        +     +F ++ Q G + 
Sbjct: 654  FRNVIETIDTTTPIGTVAATDCDADPNNILTYSL--------IGAQADKFRLDSQ-GVLY 704

Query: 535  TNKLLDRETMSG-YLLTVTARD--GGVPSLSDTTDVEISVVDVNDNEPVF-KQQLYTANI 590
                LD +   G Y L    RD  GG    +DT  V + + DVND  PVF         I
Sbjct: 705  AATELDYDVGDGSYELEAQVRDQAGG----ADTATVWVYLTDVNDEGPVFLNTDGSVYYI 760

Query: 591  MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650
             EDA +G  +  V A+DAD      I + +    +   +F IDP +GVI +         
Sbjct: 761  DEDAPLGYIIGTVYASDAD--KTDTITFGI----QGSSTFQIDPQTGVI-SRIGTGNLPE 813

Query: 651  ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF--YISENSPIGTTIGE 708
            A++     A DG     +S   V I++ DIND+ P+F  DC ++   ISE++ IGT + +
Sbjct: 814  ASYRFNVTATDG---KYTSDAEVEIQVNDINDNTPIF-PDCNSYAPSISESAAIGTFLIK 869

Query: 709  IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768
            ++A D D+G NA + Y I G   +N F+++   G    ++ T   LD E+     ++V+ 
Sbjct: 870  VQATDADKGVNAEIAYDIAG--SNNPFTIDAVTG----DISTQDPLDRET-TPTIDIVVT 922

Query: 769  AASPP--LWND---VRVEILVTDVNDNAPV--MKDFQIIFNNYKDCFPVGPFGRVPAYDA 821
            A   P  ++++     + + +TDVNDN P   ++D+ +I +N    F   P  +V   DA
Sbjct: 923  AQDNPGSIFSNQGFCIITVNITDVNDNRPTFPLEDYVVIISNTAPQF--APILKVEVEDA 980

Query: 822  DVTDKLQYRI-LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMM 880
            D+     +   L+  N  L  +N+  G +     L+         +V   DG N  K+ +
Sbjct: 981  DLPTPAGFTYGLTTQNPVLFEINQ-NGEIFPVADLSVYDDNTFNFKVEAEDGPNRAKSNV 1039

Query: 881  QLSV 884
            Q+ V
Sbjct: 1040 QVKV 1043



 Score = 77.8 bits (183), Expect = 4e-12
 Identities = 88/403 (21%), Positives = 170/403 (42%), Gaps = 40/403 (9%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDA-----DEDNRLHYEITG-GNTRGRFSITSQNG 419
           F   +Y+  ++E+ P G  V  L+          +   + YE+ G G+      ++  + 
Sbjct: 119 FADSRYQGVISENSPLGEKVRGLSDLRVVVPIYAQGMPVQYELLGQGSDNFHLEVSEDDS 178

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479
              +    PL   ++  Y LT+ A  +    + AM ++ I     + PVF  + +  S+ 
Sbjct: 179 TVGVYADAPLQVAEKEFYKLTLEAVVN---DEVAMTEVQIWVLGLHPPVFAFSSFIYSIA 235

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           E++P+GT    V ATD D+G N ++TY L            ++ F +  ++G +T   + 
Sbjct: 236 ENSPVGTIAGTVFATDEDMGENGRVTYHL---------LKLNRYFTVGQESGLVT---VT 283

Query: 540 DRETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNE-PVFKQQLYTANIMEDALVG 597
           +   +  Y + V ARD G P   S    ++ISV+  + N  P     ++  +        
Sbjct: 284 EPTPVGEYTMQVVARDAGTPFQESAPVPLQISVISSSSNMIPYGNDMMFAPDYKPSKRFR 343

Query: 598 TSV--SQVGATDADVGLNGRIHYELDPKDREEGSFV--------IDPASGVIRTNKALDR 647
             V   +    + D  +N  I       D +  ++V        ++  +G ++    L+ 
Sbjct: 344 REVLPEERVPVNEDTAINTVIFTVSSLNDTDRFAYVGTPNPLFGLNETTGEVKLLDQLNF 403

Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF--YISENSPIGTT 705
           E    H+ +    +     +  T  + I+++++N+ PP +E     +   +  ++P G +
Sbjct: 404 EQATVHEFEVEITNVENTDKRDTQRIIIEVQNVNE-PPQWEIGVYPYIEVVPVDAPTGAS 462

Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAEL 748
           I  +RA DP EG + V  Y   GG  S  F+++   G  K  L
Sbjct: 463 IFHLRASDP-EGSD-VRFYLNSGG--SGLFTVDEESGWIKTSL 501



 Score = 64.9 bits (151), Expect = 3e-08
 Identities = 148/642 (23%), Positives = 248/642 (38%), Gaps = 59/642 (9%)

Query: 245 INIRDVN---DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE---LTYTMTD 298
           IN+R VN   D+   F  S +Q  +SEN P+G  +  +        + A+   + Y +  
Sbjct: 104 INVRIVNTGRDSKLHFADSRYQGVISENSPLGEKVRGLSDLRVVVPIYAQGMPVQYELLG 163

Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358
           +  + N  L ++ D  +  VY    L    +  Y+L + A    +      A        
Sbjct: 164 QG-SDNFHLEVSEDDSTVGVYADAPLQVAEKEFYKLTLEAVVNDE-----VAMTEVQIWV 217

Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITS 416
                  F    +   +AE+ P GT   T+ ATD D  E+ R+ Y +   N   R+    
Sbjct: 218 LGLHPPVFAFSSFIYSIAENSPVGTIAGTVFATDEDMGENGRVTYHLLKLN---RYFTVG 274

Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQIN-ITDANNYAPVFENA 472
           Q   GL+TV +P    +   Y + V A D+G     S    +QI+ I+ ++N  P   + 
Sbjct: 275 QES-GLVTVTEPTPVGE---YTMQVVARDAGTPFQESAPVPLQISVISSSSNMIPYGNDM 330

Query: 473 PYTASVFEDAPIGTTVLVVS--ATDSDVGINAQI-TYSLSSEISNEA-VAHHDQQFVINP 528
            +             VL       + D  IN  I T S  ++    A V   +  F +N 
Sbjct: 331 MFAPDYKPSKRFRREVLPEERVPVNEDTAINTVIFTVSSLNDTDRFAYVGTPNPLFGLNE 390

Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL--Y 586
            TG +     L+ E  + +   V   +       DT  + I V +VN+  P ++  +  Y
Sbjct: 391 TTGEVKLLDQLNFEQATVHEFEVEITNVENTDKRDTQRIIIEVQNVNE-PPQWEIGVYPY 449

Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646
              +  DA  G S+  + A+D + G + R +          G F +D  SG I+T  +L 
Sbjct: 450 IEVVPVDAPTGASIFHLRASDPE-GSDVRFYL----NSGGSGLFTVDEESGWIKT--SLS 502

Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706
                    K +          S++   + I      PP F  +     ++E       I
Sbjct: 503 EGQGYQQGQKYILSVYAQDENGSSIPAEVNIFG-GSHPPQFTQEVYNVAVTEE-----VI 556

Query: 707 GEIRAHDPD--EGPNAVVHYSIKGGDDSNSFSLET-RQGSDKAELVTMVDLDYESPRKKY 763
           GE    D D     N  V +++   + +      +    S + +L+  VD +       Y
Sbjct: 557 GEQNVIDIDAFSFSNVAVTFALLNSETNQPIPRHSIDPSSGQIKLLEKVDREV---LDSY 613

Query: 764 ELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCF-PVGPFGRVPA- 818
            L ++A       L   VRV + VTD+ND  P  +     F N  +      P G V A 
Sbjct: 614 FLEVQATEDVQDGLSTTVRVNVEVTDINDCVPKFERETYSFRNVIETIDTTTPIGTVAAT 673

Query: 819 -YDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNV 859
             DAD  + L Y ++ G  A+   L ++ G +  + +L+ +V
Sbjct: 674 DCDADPNNILTYSLI-GAQADKFRL-DSQGVLYAATELDYDV 713


>UniRef50_A7RQM0 Cluster: Predicted protein; n=2; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 1852

 Score =  471 bits (1161), Expect = e-130
 Identities = 315/895 (35%), Positives = 465/895 (51%), Gaps = 62/895 (6%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ V D ND+ P F    Y  +V E  ++G  V  + ATD D G N ++ Y+I       
Sbjct: 672  KVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSI------- 724

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            L+  +               F +D  +G + TR  LDRE +A Y++ + A D  S V  R
Sbjct: 725  LSGNENMA------------FAMDRFTGEITTRVPLDRETIASYSLTINA-DDGSLV--R 769

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
              +  T++++I D+NDN P F+  +   ++ ED S T   V  ++ ATD D+G N A+ Y
Sbjct: 770  FMAATTVNISIADENDNQPTFTGPS-RFNISED-SPTGTRV-GQLTATDRDIGPNGAVTY 826

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            AII GN    F +D  SG +S+  TLD E + SY LV++A D GSP +S T  + +++ D
Sbjct: 827  AIISGNQGNSFQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSPQQSITASIHVSVLD 886

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            VNDNAPRF  SLF   + E+  +  ++++V+  D DEG N  +T ++     +G      
Sbjct: 887  VNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITLSL-----SGEGSDNF 941

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            TID  +G+V +   LD ET A YQL VTA DGG P +SATA               F+  
Sbjct: 942  TID-STGFVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSP 1000

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
                 + ED    T VV L ATD+D    L ++I  GN    F I   +  GLI+VA+ L
Sbjct: 1001 AQVTSIPEDVAINTHVVKLNATDSD-GTPLTFDIVEGNAGSSFKIDQSS--GLISVAKRL 1057

Query: 430  DFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
            D +    Y L V AT++G + ++      I + D N+ APVF    Y  S+ E+ PIG T
Sbjct: 1058 DRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQT 1117

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
            V  V+ATD D G NA++TY LS             +F +NP TG +TT + LDRE  + Y
Sbjct: 1118 VAKVTATDRDEGENAKVTYELS--------VGDTSKFEVNPATGLVTTKRPLDREDQASY 1169

Query: 548  LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
             L VTA D G PS S    + +++ D+NDN P F Q  YT  + E+   G+++ +V A+D
Sbjct: 1170 SLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASD 1229

Query: 608  ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
             D G NGR+ Y +        +F ID  +G I     +DRE++A+++L   A D G PP 
Sbjct: 1230 PDAGANGRVTYSI-ISGNHGNAFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPPW 1288

Query: 668  SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
             ST  V I + D ND+ P+F S+  ++ I E   IG+ +  + A D DEG NA V YSI 
Sbjct: 1289 VSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIV 1348

Query: 728  GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILV 784
             GD S +F++    G     L    +++ E+    Y L IRA+   SP + +D  + ++V
Sbjct: 1349 RGDTS-AFAINAMNG----VLTVKKEINRETV-PTYTLTIRASDRGSPMMTSDKELTVVV 1402

Query: 785  TDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILL 842
             DVNDN PV      I +  ++         V A D+DV     L+Y I+SGN+     +
Sbjct: 1403 NDVNDNPPVFNSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGNDEKRFKI 1462

Query: 843  NETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSIT 897
            N T+G +  +  L+        +EV+ TD  ++  A   +++R+I     LN IT
Sbjct: 1463 NSTSGVIMTTTPLDFEEKSQYGLEVTATD--SKYTAKTNVTIRVIN----LNDIT 1511



 Score =  447 bits (1102), Expect = e-123
 Identities = 291/789 (36%), Positives = 405/789 (51%), Gaps = 59/789 (7%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V D ND++P F +  Y+  V E  + G+ V  L A D D+G NA + Y+  LV+ DT 
Sbjct: 156 ITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYS--LVSGDT- 212

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                              F +D + G + T+ + DRE  A Y V ++A D  SP     
Sbjct: 213 -----------------SYFTVDSQ-GVIRTKGAFDRETKASYQVALRAQDGGSPSR--- 251

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           S  AT+ + I+D NDN P FS   YT SVDED+++     +  + A+D D G N+ +RY+
Sbjct: 252 SGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAI--GAAMVTVTASDKDNGNNADLRYS 309

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
              GNT   F++D+++G V++ ++LD+EQ  SY L +   D GSP  ++T+ LLIN+ D+
Sbjct: 310 FTSGNTNHAFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDI 369

Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
           NDN P F  S +Q  V EN P G    +V A D D   N  L + +      GN D   T
Sbjct: 370 NDNPPVFSPSAYQSRVKENTPAG---TQVSATDRDSSTNGALVFGIIK----GNDDGVFT 422

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
           ID  +G +  +   D E + +Y L V A D G P +  TA               F P  
Sbjct: 423 IDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSN 482

Query: 371 YEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
           Y  ++ E    G+ VVT+TATD D     RL Y +  GN +G F+I + +G   I V+  
Sbjct: 483 YSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISGNVKGAFNIDANSGS--IRVSSE 540

Query: 429 LDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
           LD +    Y L V A D G   RS +  V I + D N+ +P+F+  PY   V E +  G 
Sbjct: 541 LDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQG-PYVFRVSESSSPGH 599

Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
            +  V+ATD+D   N  + Y+LS          +   F IN  TG IT    LD E  + 
Sbjct: 600 QIGQVAATDADDSSNGDVRYALSD---------NTDVFSINTSTGLITLKTQLDYEKKTQ 650

Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
           Y++TVTA+DGG PS S  T V++ V DVNDN P F + LYT  + E+   G +V  V AT
Sbjct: 651 YMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTAT 710

Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
           DAD G NG+I Y +     E  +F +D  +G I T   LDRE++A++ L   A DG    
Sbjct: 711 DADSGANGKISYSI-LSGNENMAFAMDRFTGEITTRVPLDRETIASYSLTINADDGSLVR 769

Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
             +   V+I I D ND+ P F      F ISE+SP GT +G++ A D D GPN  V Y+I
Sbjct: 770 FMAATTVNISIADENDNQPTFTGPS-RFNISEDSPTGTRVGQLTATDRDIGPNGAVTYAI 828

Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEIL 783
             G+  NSF L+ R G     L     LD E+    Y LV++A+   SP       + + 
Sbjct: 829 ISGNQGNSFQLDPRSGI----LSVRSTLDRET-IPSYTLVVKASDAGSPQQSITASIHVS 883

Query: 784 VTDVNDNAP 792
           V DVNDNAP
Sbjct: 884 VLDVNDNAP 892



 Score =  446 bits (1099), Expect = e-123
 Identities = 292/884 (33%), Positives = 457/884 (51%), Gaps = 56/884 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I++ D ND+ P F       ++ E + +GT V  L ATD+DIG N  V Y I  ++ +  
Sbjct: 778  ISIADENDNQPTFTGPS-RFNISEDSPTGTRVGQLTATDRDIGPNGAVTYAI--ISGNQG 834

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N                  F++D RSG L  R++LDRE +  YT++VKA+D  SP   + 
Sbjct: 835  NS-----------------FQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSP---QQ 874

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S TA+IHV+++D NDN P+F +  ++  + ED SV  +  + ++K  D D G+N AI  +
Sbjct: 875  SITASIHVSVLDVNDNAPRFEKSLFSGEIREDASV--HSTVLQVKVEDKDEGSNGAITLS 932

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            + G  +   F+IDS +G V     LDYE   +Y+L + A+DGGSPS+S T Q+ I I +V
Sbjct: 933  LSGEGSD-NFTIDS-TGFVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKITIINV 990

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN P F +     S+ E+V I   +V++ A D+D      LT+ + +    GN      
Sbjct: 991  NDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDSD---GTPLTFDIVE----GNAGSSFK 1043

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            ID  SG +  + +LDRET A Y L+V AT+ G    S                  F PG 
Sbjct: 1044 IDQSSGLISVAKRLDRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNPGS 1103

Query: 371  YEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
            Y   L E+ P G  V  +TATD DE    ++ YE++ G+T  +F +    G  L+T  +P
Sbjct: 1104 YAKSLHENLPIGQTVAKVTATDRDEGENAKVTYELSVGDT-SKFEVNPATG--LVTTKRP 1160

Query: 429  LDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGT 486
            LD + +  Y L V+A D G  S +A+  I +T  D N+ +P F  + YT +V E+   G+
Sbjct: 1161 LDREDQASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTENTANGS 1220

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
             +L V A+D D G N ++TYS+ S        +H   F I+  TG IT   ++DRE ++ 
Sbjct: 1221 NILRVLASDPDAGANGRVTYSIIS-------GNHGNAFRIDSTTGRITVVGVVDREALAS 1273

Query: 547  YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
            Y LT++A+D GVP    T  V I+V D NDN P+F     +  I E   +G+ V+ V AT
Sbjct: 1274 YNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTAT 1333

Query: 607  DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
            D D G N ++ Y +   D    +F I+  +GV+   K ++RE+V T+ L   A D G+P 
Sbjct: 1334 DRDEGSNAQVFYSIVRGDTS--AFAINAMNGVLTVKKEINRETVPTYTLTIRASDRGSPM 1391

Query: 667  QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
             +S   + + + D+ND+PPVF S      + ENS   T++  + A D D G NAV+ YSI
Sbjct: 1392 MTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSI 1451

Query: 727  KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTD 786
              G+D   F + +  G     ++T   LD+E  + +Y L + A          V I V +
Sbjct: 1452 ISGNDEKRFKINSTSGV----IMTTTPLDFEE-KSQYGLEVTATDSKYTAKTNVTIRVIN 1506

Query: 787  VNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETT 846
            +ND  P         +  ++        +V A D D    L Y I+ G +++   +++ +
Sbjct: 1507 LNDITPAFTQQNYTASVRENSPTSTSVVKVSASDRDSFGSLSYSIVGGKDSDKFSIDQRS 1566

Query: 847  GSMTLSPQLNTNVPKLATMEVSVTDGVN-EIKAMMQLSVRLITE 889
            G ++ +  L+  +  L  ++V VTD  N  +  +  ++++++ E
Sbjct: 1567 GIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDE 1610



 Score =  440 bits (1085), Expect = e-121
 Identities = 283/867 (32%), Positives = 447/867 (51%), Gaps = 56/867 (6%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I +LD ND+ PVF   QY ASV E  + G  ++T+ A+D+D G NA++ Y+    T+  
Sbjct: 258  EIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSF---TSGN 314

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             N                  F +D  +G +    SLD E+ + Y + +  TD+ SP    
Sbjct: 315  TN----------------HAFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSP---P 355

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            L+ T+ + +N+ D NDN P FS   Y   V E     + P   ++ ATD D   N A+ +
Sbjct: 356  LTDTSHLLINVNDINDNPPVFSPSAYQSRVKE-----NTPAGTQVSATDRDSSTNGALVF 410

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             II GN    F+ID  +G +S+ K+ DYE    Y L ++A+D G P + +T Q+ I I D
Sbjct: 411  GIIKGNDDGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIED 470

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            VND++P F  S + + + E+  IG ++V V A D D G    L Y +     +GNV    
Sbjct: 471  VNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRL----ISGNVKGAF 526

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             ID  SG +  S +LDRET   Y L V A DGG   RS++                F  G
Sbjct: 527  NIDANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQ-G 585

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
             Y   ++E   PG  +  + ATDAD+ +         +    FSI +    GLIT+   L
Sbjct: 586  PYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSDNTDVFSINTST--GLITLKTQL 643

Query: 430  DFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
            D++++ +Y++TV+A D G   RS   +V++ + D N+  P F  + YT +V E+   G  
Sbjct: 644  DYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVA 703

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
            V  V+ATD+D G N +I+YS+ S   NE +A     F ++  TG ITT   LDRET++ Y
Sbjct: 704  VCYVTATDADSGANGKISYSILS--GNENMA-----FAMDRFTGEITTRVPLDRETIASY 756

Query: 548  LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
             LT+ A DG +      T V IS+ D NDN+P F       NI ED+  GT V Q+ ATD
Sbjct: 757  SLTINADDGSLVRFMAATTVNISIADENDNQPTFTGP-SRFNISEDSPTGTRVGQLTATD 815

Query: 608  ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
             D+G NG + Y +     +  SF +DP SG++     LDRE++ ++ L   A D G+P Q
Sbjct: 816  RDIGPNGAVTYAI-ISGNQGNSFQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSPQQ 874

Query: 668  SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
            S T  +H+ + D+ND+ P FE    +  I E++ + +T+ +++  D DEG N  +  S+ 
Sbjct: 875  SITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITLSL- 933

Query: 728  GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILV 784
             G+ S++F++++        +++   LDYE+    Y+L + A    SP      +V+I +
Sbjct: 934  SGEGSDNFTIDS-----TGFVLSKTPLDYET-TAAYQLTVTARDGGSPSKSATAQVKITI 987

Query: 785  TDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNE 844
             +VNDN P       + +  +D        ++ A D+D T  L + I+ GN  +   +++
Sbjct: 988  INVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDSDGT-PLTFDIVEGNAGSSFKIDQ 1046

Query: 845  TTGSMTLSPQLNTNVPKLATMEVSVTD 871
            ++G ++++ +L+       T+ V  T+
Sbjct: 1047 SSGLISVAKRLDRETTANYTLVVRATE 1073



 Score =  416 bits (1024), Expect = e-114
 Identities = 290/861 (33%), Positives = 431/861 (50%), Gaps = 63/861 (7%)

Query: 2    SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
            S+   IH  ++VLD ND++P FE   +   +RE AS  +TVL +K  D+D G N  +   
Sbjct: 875  SITASIH--VSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITL- 931

Query: 62   IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121
                   +L+ E +            D F ID  +G +L++  LD E  A Y + V A D
Sbjct: 932  -------SLSGEGS------------DNFTIDS-TGFVLSKTPLDYETTAAYQLTVTARD 971

Query: 122  QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181
              SP     S+TA + + II+ NDN P F       S+ ED+++  N  + K+ ATD+D 
Sbjct: 972  GGSPSK---SATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAI--NTHVVKLNATDSD- 1025

Query: 182  GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
               + + + I+ GN    F ID  SG +S+ K LD E   +Y LV+RA + GS   S   
Sbjct: 1026 --GTPLTFDIVEGNAGSSFKIDQSSGLISVAKRLDRETTANYTLVVRATETGSQGESVYN 1083

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
               I + DVNDNAP F    + +S+ EN+PIG ++ +V A D DEG NA++TY ++  D 
Sbjct: 1084 NATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTYELSVGDT 1143

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
            +        ++P +G V T   LDRE QA Y L VTA D G P +SA A           
Sbjct: 1144 S-----KFEVNPATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQSAVAAITLTINDLND 1198

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419
                F   +Y + + E+   G+ ++ + A+D D   + R+ Y I  GN    F I S  G
Sbjct: 1199 NSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSIISGNHGNAFRIDSTTG 1258

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTAS 477
            R  ITV   +D +    Y LT+SA DSG      TA V I + D N+ +P+F +   +  
Sbjct: 1259 R--ITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYG 1316

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            + E   IG+ V VV+ATD D G NAQ+ YS+        V      F IN   G +T  K
Sbjct: 1317 IDEGVSIGSRVAVVTATDRDEGSNAQVFYSI--------VRGDTSAFAINAMNGVLTVKK 1368

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
             ++RET+  Y LT+ A D G P ++   ++ + V DVNDN PVF  Q Y  ++ E++   
Sbjct: 1369 EINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQS 1428

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
            TSV  V A D+DVG N  + Y +     +E  F I+  SGVI T   LD E  + + L+ 
Sbjct: 1429 TSVLTVAADDSDVGANAVLRYSI-ISGNDEKRFKINSTSGVIMTTTPLDFEEKSQYGLEV 1487

Query: 658  VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
             A D     +++   V I++ ++ND  P F     T  + ENSP  T++ ++ A D D  
Sbjct: 1488 TATDSKYTAKTN---VTIRVINLNDITPAFTQQNYTASVRENSPTSTSVVKVSASDRDSF 1544

Query: 718  PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND 777
             +  + YSI GG DS+ FS++ R G        ++D +  S       V  A +PPL N 
Sbjct: 1545 GS--LSYSIVGGKDSDKFSIDQRSGI--ISTADVLDRELVSLYAIQVRVTDAGNPPLSNL 1600

Query: 778  VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGN 835
              V I + D NDN+P         +  ++  P     ++ A DAD     ++ Y  LS N
Sbjct: 1601 TWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDADEGTNARITYN-LSRN 1659

Query: 836  NANLILLNETTGSMTLSPQLN 856
            +A   ++  ++G +TL+  L+
Sbjct: 1660 DA--FMIGASSGVITLAQPLD 1678



 Score =  413 bits (1018), Expect = e-113
 Identities = 289/850 (34%), Positives = 430/850 (50%), Gaps = 62/850 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I + D NDHSPVF    Y   + E    G+TV+T+ ATD D G    +EY   L++ +  
Sbjct: 466  IFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEY--RLISGN-- 521

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           V+  F ID  SG++   + LDRE    Y++ V+A D  S  + R 
Sbjct: 522  ---------------VKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARDGGS--TSRS 564

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            SST  + + + D NDN P F +  Y   V E  S +    I ++ ATDAD  +N  +RYA
Sbjct: 565  SST-RVTIALQDINDNSPIF-QGPYVFRVSE--SSSPGHQIGQVAATDADDSSNGDVRYA 620

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
             +  NT + FSI++ +G ++L   LDYE+   Y + + A+DGG+PSRS+ T + + + DV
Sbjct: 621  -LSDNTDV-FSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDV 678

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN P+F  SL+  +V EN+  G ++  V A DAD G N +++Y++     +GN ++   
Sbjct: 679  NDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSI----LSGNENMAFA 734

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            +D  +G + T   LDRET A Y L + A D G   R   AT                 G 
Sbjct: 735  MDRFTGEITTRVPLDRETIASYSLTINA-DDGSLVRFMAATTVNISIADENDNQPTFTGP 793

Query: 371  YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
                ++ED P GT V  LTATD D   +  + Y I  GN    F +  ++  G+++V   
Sbjct: 794  SRFNISEDSPTGTRVGQLTATDRDIGPNGAVTYAIISGNQGNSFQLDPRS--GILSVRST 851

Query: 429  LDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
            LD +    Y L V A+D+G   +S TA + +++ D N+ AP FE + ++  + EDA + +
Sbjct: 852  LDRETIPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHS 911

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
            TVL V   D D G N  IT SLS E S+         F I+  TG + +   LD ET + 
Sbjct: 912  TVLQVKVEDKDEGSNGAITLSLSGEGSD--------NFTID-STGFVLSKTPLDYETTAA 962

Query: 547  YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
            Y LTVTARDGG PS S T  V+I++++VNDN P F       +I ED  + T V ++ AT
Sbjct: 963  YQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNAT 1022

Query: 607  DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
            D+D      + +++  +     SF ID +SG+I   K LDRE+ A + L   A + G+  
Sbjct: 1023 DSD---GTPLTFDI-VEGNAGSSFKIDQSSGLISVAKRLDRETTANYTLVVRATETGSQG 1078

Query: 667  QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
            +S      I++ D+ND+ PVF        + EN PIG T+ ++ A D DEG NA V Y +
Sbjct: 1079 ESVYNNATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTYEL 1138

Query: 727  KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEIL 783
              GD S  F +    G     + T   LD E  +  Y L + A     P       + + 
Sbjct: 1139 SVGDTS-KFEVNPATGL----VTTKRPLDRED-QASYSLRVTAMDHGKPSQSAVAAITLT 1192

Query: 784  VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLIL 841
            + D+NDN+P     +      ++        RV A D D     ++ Y I+SGN+ N   
Sbjct: 1193 INDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSIISGNHGNAFR 1252

Query: 842  LNETTGSMTL 851
            ++ TTG +T+
Sbjct: 1253 IDSTTGRITV 1262



 Score =  412 bits (1015), Expect = e-113
 Identities = 289/869 (33%), Positives = 433/869 (49%), Gaps = 66/869 (7%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I+V D ND++P F +  Y  ++RE  +    V  + ATD+D G NA + Y++        
Sbjct: 58  IDVKDENDNAPEFPLNSYVFNIREN-TPAAQVAIVTATDRDSGTNAAITYSL-------- 108

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           ++ F ++ ++G + T   LD E    YT+ + A D         
Sbjct: 109 -------------FSGENKFMMNSKTGEIRTVTPLDHETKDSYTMRISAFDGK------- 148

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +T    + + D NDN P F+   Y   V ED++V    ++ ++ A D DVG N+ + Y+
Sbjct: 149 HTTFVPLITVDDVNDNAPFFALSVYKTGVYEDVAV--GSIVRQLTAVDLDVGINARLSYS 206

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
           ++ G+T   F++DS  G +      D E   SY++ +RAQDGGSPSRS    + I I DV
Sbjct: 207 LVSGDTS-YFTVDS-QGVIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDV 264

Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
           NDN P F ++ +  SV E+V IG ++V V A D D G NA+L Y+ T    +GN +   T
Sbjct: 265 NDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFT----SGNTNHAFT 320

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
           +D  +G V  S  LD E ++ Y L ++ TD G PP + T+               F P  
Sbjct: 321 LDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSA 380

Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
           Y+  + E+ P GT  V+ T  D+  +  L + I  GN  G F+I      G+I++A+  D
Sbjct: 381 YQSRVKENTPAGTQ-VSATDRDSSTNGALVFGIIKGNDDGVFTI--DGSTGIISIAKSPD 437

Query: 431 FKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
           ++ + RY LTV A D G   + DTA V I I D N+++PVF  + Y+  + E   IG+TV
Sbjct: 438 YENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTV 497

Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
           + V+ATD D G   ++ Y L S     A       F I+  +G+I  +  LDRET   Y 
Sbjct: 498 VTVTATDLDSGPRGRLEYRLISGNVKGA-------FNIDANSGSIRVSSELDRETTPSYS 550

Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
           L V ARDGG  S S +T V I++ D+NDN P+F Q  Y   + E +  G  + QV ATDA
Sbjct: 551 LQVEARDGGSTSRSSSTRVTIALQDINDNSPIF-QGPYVFRVSESSSPGHQIGQVAATDA 609

Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
           D   NG + Y L   D  +  F I+ ++G+I     LD E    + +   A DGGTP +S
Sbjct: 610 DDSSNGDVRYAL--SDNTD-VFSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRS 666

Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
           S  +V + ++D+ND+PP F     T  + EN   G  +  + A D D G N  + YSI  
Sbjct: 667 SLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILS 726

Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL---WNDVRVEILVT 785
           G+++ +F+++   G    E+ T V LD E+    Y L I A    L        V I + 
Sbjct: 727 GNENMAFAMDRFTG----EITTRVPLDRET-IASYSLTINADDGSLVRFMAATTVNISIA 781

Query: 786 DVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADV--TDKLQYRILSGNNANLILL 842
           D NDN P        FN  +D  P G   G++ A D D+     + Y I+SGN  N   L
Sbjct: 782 DENDNQPTFTG-PSRFNISEDS-PTGTRVGQLTATDRDIGPNGAVTYAIISGNQGNSFQL 839

Query: 843 NETTGSMTLSPQLNTNVPKLATMEVSVTD 871
           +  +G +++   L+       T+ V  +D
Sbjct: 840 DPRSGILSVRSTLDRETIPSYTLVVKASD 868



 Score =  407 bits (1001), Expect = e-111
 Identities = 274/797 (34%), Positives = 409/797 (51%), Gaps = 51/797 (6%)

Query: 87  QDVFRIDGRSGALLTRA-SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145
           Q +F ID  +G++ T     DRE  +RY + V A D A+           + +++ D+ND
Sbjct: 9   QGMFTIDSSTGSITTTGRKFDRESESRYRLTVLAQDAANRCH---KGRTVVVIDVKDEND 65

Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205
           N P+F   +Y  ++ E+   T    +A + ATD D G N+AI Y++  G  +  F ++S 
Sbjct: 66  NAPEFPLNSYVFNIREN---TPAAQVAIVTATDRDSGTNAAITYSLFSGENK--FMMNSK 120

Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265
           +G++  V  LD+E   SY + I A DG    +  T   LI + DVNDNAP F  S+++  
Sbjct: 121 TGEIRTVTPLDHETKDSYTMRISAFDG----KHTTFVPLITVDDVNDNAPFFALSVYKTG 176

Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325
           V E+V +G  + ++ A D D G+NA L+Y++   D +       T+D + G + T G  D
Sbjct: 177 VYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGDTS-----YFTVDSQ-GVIRTKGAFD 230

Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
           RET+A YQ+ + A DGG P RS  AT              F   QY   + ED   G  +
Sbjct: 231 RETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAM 290

Query: 386 VTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443
           VT+TA+D D  N   L Y  T GNT   F++ +    G++TV++ LDF+Q   Y L +S 
Sbjct: 291 VTVTASDKDNGNNADLRYSFTSGNTNHAFTLDAVT--GVVTVSRSLDFEQRSSYALGLSV 348

Query: 444 TDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501
           TD G    +DT+ + IN+ D N+  PVF  + Y + V E+ P GT    VSATD D   N
Sbjct: 349 TDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGTQ---VSATDRDSSTN 405

Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL 561
             + + +          + D  F I+  TG I+  K  D E  + Y LTV ARD GVP  
Sbjct: 406 GALVFGIIK-------GNDDGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVK 458

Query: 562 SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621
            DT  V I + DVND+ PVF    Y+  I E  ++G++V  V ATD D G  GR+ Y L 
Sbjct: 459 YDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRL- 517

Query: 622 PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681
                +G+F ID  SG IR +  LDRE+  ++ L+  A DGG+  +SS+  V I ++DIN
Sbjct: 518 ISGNVKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDIN 577

Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741
           D+ P+F+     F +SE+S  G  IG++ A D D+  N  V Y++   D+++ FS+ T  
Sbjct: 578 DNSPIFQGP-YVFRVSESSSPGHQIGQVAATDADDSSNGDVRYAL--SDNTDVFSINTST 634

Query: 742 GSDKAELVTM-VDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDF 797
           G     L+T+   LDYE  + +Y + + A    +P   +   V+++V DVNDN P     
Sbjct: 635 G-----LITLKTQLDYEK-KTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKS 688

Query: 798 QIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQL 855
                  ++         V A DAD     K+ Y ILSGN      ++  TG +T    L
Sbjct: 689 LYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNENMAFAMDRFTGEITTRVPL 748

Query: 856 NTNVPKLATMEVSVTDG 872
           +       ++ ++  DG
Sbjct: 749 DRETIASYSLTINADDG 765



 Score =  402 bits (991), Expect = e-110
 Identities = 274/787 (34%), Positives = 405/787 (51%), Gaps = 56/787 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I VLD ND++PVF    Y  S+ E    G TV  + ATD+D G+NA+V Y  EL   DT 
Sbjct: 1087 IRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTY--ELSVGDTS 1144

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F ++  +G + T+  LDRE  A Y++ V A D   P     
Sbjct: 1145 K------------------FEVNPATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQ--- 1183

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S+ A I + I D NDN PQFS+  YT++V E+ +   N  I ++ A+D D GAN  + Y+
Sbjct: 1184 SAVAAITLTINDLNDNSPQFSQSKYTLTVTENTANGSN--ILRVLASDPDAGANGRVTYS 1241

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            II GN    F IDS +G +++V  +D E + SY L I A+D G P   +T  + I + D 
Sbjct: 1242 IISGNHGNAFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADE 1301

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN+P F ++     + E V IG  +  V A D DEG NA++ Y++   D +        
Sbjct: 1302 NDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIVRGDTSA-----FA 1356

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            I+  +G +    +++RET   Y L + A+D G P  ++                 F    
Sbjct: 1357 INAMNGVLTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQS 1416

Query: 371  YEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQP 428
            Y   + E+    T V+T+ A D+D      L Y I  GN   RF I S +G  +I    P
Sbjct: 1417 YIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGNDEKRFKINSTSG--VIMTTTP 1474

Query: 429  LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
            LDF+++ +Y L V+ATDS   + T  V I + + N+  P F    YTASV E++P  T+V
Sbjct: 1475 LDFEEKSQYGLEVTATDSKYTAKTN-VTIRVINLNDITPAFTQQNYTASVRENSPTSTSV 1533

Query: 489  LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
            + VSA+D D      ++YS+     ++       +F I+ ++G I+T  +LDRE +S Y 
Sbjct: 1534 VKVSASDRDSF--GSLSYSIVGGKDSD-------KFSIDQRSGIISTADVLDRELVSLYA 1584

Query: 549  LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
            + V   D G P LS+ T V I ++D NDN P F    Y+++I+E++   +   ++ ATDA
Sbjct: 1585 IQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDA 1644

Query: 609  DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
            D G N RI Y L   D    +F+I  +SGVI   + LDRE+ +T+DL   A D GTPPQ+
Sbjct: 1645 DEGTNARITYNLSRND----AFMIGASSGVITLAQPLDRENKSTYDLAIQARDHGTPPQA 1700

Query: 669  STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
            S++ + + + DIND  P+  S  L   + EN P  T +  I A D D G NA + +S+  
Sbjct: 1701 SSITIRVTVIDINDHRPLINSSSLRGSVRENQPKETHVMRILASDADTGLNAELTFSLLS 1760

Query: 729  GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVT 785
             +  + F+L+   G    ++ T V LD E  +  Y L I  A   +P L +   V I V 
Sbjct: 1761 NEHKSVFTLDNTTG----DISTKVPLDREQ-QAVYTLRIGVADKGNPSLSSVADVIIDVI 1815

Query: 786  DVNDNAP 792
            D +DN P
Sbjct: 1816 DEDDNCP 1822



 Score =  384 bits (945), Expect = e-104
 Identities = 281/877 (32%), Positives = 429/877 (48%), Gaps = 73/877 (8%)

Query: 8    HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
            H  INV D ND+ PVF    Y++ V+E   +GT V    ATD+D   N  + + I     
Sbjct: 361  HLLINVNDINDNPPVFSPSAYQSRVKENTPAGTQV---SATDRDSSTNGALVFGI----- 412

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
              +   D              VF IDG +G +    S D E   RY + V+A D+  PV 
Sbjct: 413  --IKGND------------DGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVK 458

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
                 TA + + I D ND+ P FS   Y+  + E  S      +  + ATD D G    +
Sbjct: 459  ---YDTAQVTIFIEDVNDHSPVFSPSNYSKQIPE--STVIGSTVVTVTATDLDSGPRGRL 513

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
             Y +I GN +  F+ID+ SG + +   LD E   SY L + A+DGGS SRS++T++ I +
Sbjct: 514  EYRLISGNVKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIAL 573

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            +D+NDN+P  +   +   VSE+   G+ I +V A DAD+  N ++ Y ++D     N D+
Sbjct: 574  QDINDNSP-IFQGPYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSD-----NTDV 627

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
              +I+  +G +    QLD E + +Y + VTA DGG P RS+                 F 
Sbjct: 628  -FSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFA 686

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITV 425
               Y   + E+   G  V  +TATDAD   + ++ Y I  GN    F++    G   IT 
Sbjct: 687  KSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNENMAFAMDRFTGE--ITT 744

Query: 426  AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
              PLD +    Y LT++A D           V I+I D N+  P F   P   ++ ED+P
Sbjct: 745  RVPLDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTF-TGPSRFNISEDSP 803

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
             GT V  ++ATD D+G N  +TY++ S        +    F ++P++G ++    LDRET
Sbjct: 804  TGTRVGQLTATDRDIGPNGAVTYAIIS-------GNQGNSFQLDPRSGILSVRSTLDRET 856

Query: 544  MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
            +  Y L V A D G P  S T  + +SV+DVNDN P F++ L++  I EDA V ++V QV
Sbjct: 857  IPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQV 916

Query: 604  GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
               D D G NG I   L  +  +  +F ID ++G + +   LD E+ A + L   A DGG
Sbjct: 917  KVEDKDEGSNGAITLSLSGEGSD--NFTID-STGFVLSKTPLDYETTAAYQLTVTARDGG 973

Query: 664  TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
            +P +S+T  V I I ++ND+ P F S      I E+  I T + ++ A D D  P   + 
Sbjct: 974  SPSKSATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDSDGTP---LT 1030

Query: 724  YSIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVIRAA-----SPPLWND 777
            + I  G+  +SF ++   G     L+++   LD E+    Y LV+RA         ++N+
Sbjct: 1031 FDIVEGNAGSSFKIDQSSG-----LISVAKRLDRET-TANYTLVVRATETGSQGESVYNN 1084

Query: 778  VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTD--KLQYRILSG 834
              + +L  DVNDNAPV        + +++  P+G    +V A D D  +  K+ Y +  G
Sbjct: 1085 ATIRVL--DVNDNAPVFNPGSYAKSLHEN-LPIGQTVAKVTATDRDEGENAKVTYELSVG 1141

Query: 835  NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            + +    +N  TG +T    L+       ++ V+  D
Sbjct: 1142 DTSK-FEVNPATGLVTTKRPLDREDQASYSLRVTAMD 1177



 Score =  382 bits (941), Expect = e-104
 Identities = 277/891 (31%), Positives = 447/891 (50%), Gaps = 66/891 (7%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I +++ ND+ P F       S+ E  +  T V+ L ATD D         T ++V  + 
Sbjct: 984  KITIINVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDSD-----GTPLTFDIVEGNA 1038

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             +                  F+ID  SG +     LDRE  A YT++V+AT+  S   + 
Sbjct: 1039 GSS-----------------FKIDQSSGLISVAKRLDRETTANYTLVVRATETGSQ-GES 1080

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            + + ATI V  +D NDN P F+  +Y  S+ E++ +     +AK+ ATD D G N+ + Y
Sbjct: 1081 VYNNATIRV--LDVNDNAPVFNPGSYAKSLHENLPI--GQTVAKVTATDRDEGENAKVTY 1136

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             +  G+T  +F ++  +G V+  + LD E   SY L + A D G PS+S    + + I D
Sbjct: 1137 ELSVGDTS-KFEVNPATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQSAVAAITLTIND 1195

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            +NDN+P+F  S +  +V+EN   G +I+RV A D D G N  +TY++     +GN     
Sbjct: 1196 LNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSII----SGNHGNAF 1251

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             ID  +G +   G +DRE  A Y L ++A D G PP  +TA               F   
Sbjct: 1252 RIDSTTGRITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASN 1311

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
            +    + E    G+ V  +TATD DE +  ++ Y I  G+T   F+I + NG  ++TV +
Sbjct: 1312 ETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIVRGDTSA-FAINAMNG--VLTVKK 1368

Query: 428  PLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIG 485
             ++ +    Y LT+ A+D G    T+  ++ +   D N+  PVF +  Y  SV E++   
Sbjct: 1369 EINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQS 1428

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
            T+VL V+A DSDVG NA + YS+ S        + +++F IN  +G I T   LD E  S
Sbjct: 1429 TSVLTVAADDSDVGANAVLRYSIIS-------GNDEKRFKINSTSGVIMTTTPLDFEEKS 1481

Query: 546  GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
             Y L VTA D      +  T+V I V+++ND  P F QQ YTA++ E++   TSV +V A
Sbjct: 1482 QYGLEVTATDS---KYTAKTNVTIRVINLNDITPAFTQQNYTASVRENSPTSTSVVKVSA 1538

Query: 606  TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
            +D D    G + Y +    ++   F ID  SG+I T   LDRE V+ + ++    D G P
Sbjct: 1539 SDRDSF--GSLSYSI-VGGKDSDKFSIDQRSGIISTADVLDRELVSLYAIQVRVTDAGNP 1595

Query: 666  PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
            P S+   V IKI D ND+ P F+S   +  I ENS   +   ++ A D DEG NA + Y+
Sbjct: 1596 PLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDADEGTNARITYN 1655

Query: 726  IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEI 782
            +   D   +F +    G+    +     LD E+ +  Y+L I+A    +PP  + + + +
Sbjct: 1656 LSRND---AFMI----GASSGVITLAQPLDREN-KSTYDLAIQARDHGTPPQASSITIRV 1707

Query: 783  LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLI 840
             V D+ND+ P++    +  +  ++        R+ A DAD  +  +L + +LS  + ++ 
Sbjct: 1708 TVIDINDHRPLINSSSLRGSVRENQPKETHVMRILASDADTGLNAELTFSLLSNEHKSVF 1767

Query: 841  LLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEE 890
             L+ TTG ++    L+     + T+ + V D G   + ++  + + +I E+
Sbjct: 1768 TLDNTTGDISTKVPLDREQQAVYTLRIGVADKGNPSLSSVADVIIDVIDED 1818



 Score =  351 bits (862), Expect = 2e-94
 Identities = 227/707 (32%), Positives = 363/707 (51%), Gaps = 47/707 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + + D ND+SP F   +Y  +V E  ++G+ +L + A+D D G N  V Y+I  ++ +  
Sbjct: 1191 LTINDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSI--ISGNHG 1248

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N                  FRID  +G +     +DRE +A Y + + A D   P     
Sbjct: 1249 N-----------------AFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPP---W 1288

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             STA + + + D+NDN P F+    +  +DE +S+     +A + ATD D G+N+ + Y+
Sbjct: 1289 VSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSR--VAVVTATDRDEGSNAQVFYS 1346

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I+ G+T   F+I++++G +++ K ++ E V +Y L IRA D GSP  ++  +L + + DV
Sbjct: 1347 IVRGDTSA-FAINAMNGVLTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDV 1405

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN P F +  +  SV EN     S++ V A D+D G NA L Y++     +GN +    
Sbjct: 1406 NDNPPVFNSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSII----SGNDEKRFK 1461

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            I+  SG + T+  LD E +++Y L VTATD      +A                 F    
Sbjct: 1462 INSTSGVIMTTTPLDFEEKSQYGLEVTATDS---KYTAKTNVTIRVINLNDITPAFTQQN 1518

Query: 371  YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
            Y   + E+ P  T VV ++A+D D    L Y I GG    +FSI  ++G  +I+ A  LD
Sbjct: 1519 YTASVRENSPTSTSVVKVSASDRDSFGSLSYSIVGGKDSDKFSIDQRSG--IISTADVLD 1576

Query: 431  FKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
             +    Y + V  TD+G    S+   V I I D N+ +P F+++ Y++S+ E++   +  
Sbjct: 1577 RELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFS 1636

Query: 489  LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
              ++ATD+D G NA+ITY+LS    N+A       F+I   +G IT  + LDRE  S Y 
Sbjct: 1637 FKLAATDADEGTNARITYNLSR---NDA-------FMIGASSGVITLAQPLDRENKSTYD 1686

Query: 549  LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
            L + ARD G P  + +  + ++V+D+ND+ P+        ++ E+    T V ++ A+DA
Sbjct: 1687 LAIQARDHGTPPQASSITIRVTVIDINDHRPLINSSSLRGSVRENQPKETHVMRILASDA 1746

Query: 609  DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
            D GLN  + + L   +  +  F +D  +G I T   LDRE  A + L+    D G P  S
Sbjct: 1747 DTGLNAELTFSL-LSNEHKSVFTLDNTTGDISTKVPLDREQQAVYTLRIGVADKGNPSLS 1805

Query: 669  STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
            S   V I + D +D+ P F+       ISE+ P G +I ++ A D D
Sbjct: 1806 SVADVIIDVIDEDDNCPRFQPTEYNVTISESLPRGASIVQVTARDID 1852



 Score =  329 bits (809), Expect = 6e-88
 Identities = 224/692 (32%), Positives = 346/692 (50%), Gaps = 40/692 (5%)

Query: 189 YAIIGGNTQMQFSIDSLSGDVSLV-KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
           Y+I+ GN Q  F+IDS +G ++   +  D E    YRL + AQD  +      T ++I++
Sbjct: 1   YSIMDGNDQGMFTIDSSTGSITTTGRKFDRESESRYRLTVLAQDAANRCHKGRTVVVIDV 60

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
           +D NDNAP F  + +  ++ EN P    +  V A D D G NA +TY++    ++G  + 
Sbjct: 61  KDENDNAPEFPLNSYVFNIRENTPAA-QVAIVTATDRDSGTNAAITYSL----FSG--EN 113

Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
              ++ ++G + T   LD ET+  Y + ++A DG    +  T                F 
Sbjct: 114 KFMMNSKTGEIRTVTPLDHETKDSYTMRISAFDG----KHTTFVPLITVDDVNDNAPFFA 169

Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITV 425
              Y+  + ED   G+ V  LTA D D   + RL Y +  G+T   F++ SQ   G+I  
Sbjct: 170 LSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGDT-SYFTVDSQ---GVIRT 225

Query: 426 AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
               D + +  Y + + A D G   RS  A V+I I D N+  PVF +A YTASV ED  
Sbjct: 226 KGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVA 285

Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
           IG  ++ V+A+D D G NA + YS +S  +N A       F ++  TG +T ++ LD E 
Sbjct: 286 IGAAMVTVTASDKDNGNNADLRYSFTSGNTNHA-------FTLDAVTGVVTVSRSLDFEQ 338

Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
            S Y L ++  D G P L+DT+ + I+V D+NDN PVF    Y + + E+   GT   QV
Sbjct: 339 RSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGT---QV 395

Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
            ATD D   NG + + +  K  ++G F ID ++G+I   K+ D E+   +DL   A D G
Sbjct: 396 SATDRDSSTNGALVFGI-IKGNDDGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRG 454

Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
            P +  T  V I IED+ND  PVF     +  I E++ IG+T+  + A D D GP   + 
Sbjct: 455 VPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLE 514

Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRV 780
           Y +  G+   +F+++   GS +       +LD E+    Y L + A    S    +  RV
Sbjct: 515 YRLISGNVKGAFNIDANSGSIRVS----SELDRET-TPSYSLQVEARDGGSTSRSSSTRV 569

Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLI 840
            I + D+NDN+P+ +    +F   +   P    G+V A DAD +     R    +N ++ 
Sbjct: 570 TIALQDINDNSPIFQG-PYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSDNTDVF 628

Query: 841 LLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            +N +TG +TL  QL+        + V+  DG
Sbjct: 629 SINTSTGLITLKTQLDYEKKTQYMVTVTAKDG 660


>UniRef50_Q6W4W6 Cluster: CHz-cadherin; n=19; Euteleostomi|Rep:
            CHz-cadherin - Gallus gallus (Chicken)
          Length = 2819

 Score =  468 bits (1153), Expect = e-129
 Identities = 452/1650 (27%), Positives = 712/1650 (43%), Gaps = 161/1650 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +NV D ND+ P F    YE SV EGA  GT+V+ + ATD D G + +V Y I L  A   
Sbjct: 1031 VNVTDVNDNVPFFVSSNYEVSVPEGADVGTSVVQVLATDLDSGLHGQVRYFI-LKDAS-- 1087

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
              ED               F I+  +G + T AS DREK A Y + V++ D +      +
Sbjct: 1088 --ED------------YQFFTIEPETGIISTHASFDREKRASYLIEVQSQDSSESARPGV 1133

Query: 131  -----SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
                 + TA + + + D NDN P F +  Y VSVDED  V  +PV+    A D D GAN+
Sbjct: 1134 HGHPNTDTAYVRIFVSDVNDNAPAFPQPVYEVSVDEDRDV-GSPVVT-ATADDRDEGANA 1191

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
             +RY I  GNT+  F ++  +G V +V++LDYE+ + Y L + A DG      N T ++I
Sbjct: 1192 KLRYQITSGNTKGVFDVEPEAGTVFIVQSLDYEEEQRYELRLVASDG---KWENHTLIII 1248

Query: 246  NIRDVNDNAPRFYTSLFQESVSENV-PIGYSIVRVQAYDADEGVNAE-LTYTMTDKDYTG 303
            N+ + ND AP F  + +  S+ E +  +   +++V A D D+  +   L+Y++    +  
Sbjct: 1249 NVVNKNDEAPVFTQNEYHGSILEELTDLPVFVLKVSATDPDQEADQNALSYSL----HGQ 1304

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
                  +I+  +G +  + +LDRE ++ ++ LV ATD      +  A             
Sbjct: 1305 GAGSEFSINENTGEISANRRLDREKRSTWRFLVLATDESGEGLTGFADVVIEVRDTNDNA 1364

Query: 364  XXFM---PGQYEVELAEDEPPGTPVVTLTATDADEDN---------RLHYEITGGNTRGR 411
              F+      +   + ED P  T V+ +TA D D+           R+   +        
Sbjct: 1365 PLFLCVSDDCFMGYVPEDSPADTAVMEMTAVDLDDPKASTHAVLTYRIIQNVQNEINLNL 1424

Query: 412  FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN 471
            FSI   +G  + TV   LD ++  +Y+L V A D GG + T    I +TD N++APVF  
Sbjct: 1425 FSINPVSGT-ICTVLGSLDREKVDKYLLVVEARDGGGLTGTGTATILVTDVNDHAPVFLQ 1483

Query: 472  APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
              YTA V E+A I T V VVSA D D G NA +T+S+   +  +       +       G
Sbjct: 1484 RIYTAFVSENASINTEVAVVSAMDRDEGENAMVTFSI---LDGDNDCKFSIETDKGNNCG 1540

Query: 532  AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY-TANI 590
             I   K +D E     +  +T +   +   S    V I V D ND+ PVF  Q Y  A++
Sbjct: 1541 FIHLRKQIDFEKPHERVFNLTLKAEDMDFFSIAHCV-IYVEDANDHAPVFYPQFYEVASL 1599

Query: 591  MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650
             ED  VGT V QV A D D GLNGR  + L  K    G F +  + G +     LD E+V
Sbjct: 1600 AEDVPVGTKVVQVSAVDLDSGLNGRFSFHLLNKSDPGGQFSV-ASDGWVIVAGVLDHETV 1658

Query: 651  ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN--SPIGTTIGE 708
              + L  +A D G PP + +  V + ++D+ND+ P FE+      + EN  SP    + E
Sbjct: 1659 TQYQLIVIATDMGQPPLACSATVLVTLQDVNDNGPEFEAH-YNPVVWENTASPQSVQMNE 1717

Query: 709  ----IRAHDPDEGPNAV--VHYSIKGGDDSNSFSLET-RQGSDKAELVTMVDLDYESPRK 761
                + A D D   N      + +   D   +F L+    GS     +   D +      
Sbjct: 1718 TSTLLYAKDRDTAANGAPFSFHLLSNFDSLGNFHLQDFHNGSALLTALHTFDREVHKVFH 1777

Query: 762  KYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDA 821
               L+  +  PP+ +   + + + D ND+       + +  +Y    P    G+V A D 
Sbjct: 1778 LPILITDSGIPPMSSTNTLTVNIGDQNDHPHSAGYMECLIYSYDGILPTTVLGQVLAPDG 1837

Query: 822  DVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGV-NEIKAMM 880
            D  D+  Y+   G  +   +LN+ +G +T+        P    ++V V DGV  ++ + +
Sbjct: 1838 DDWDRKIYQ-FEGKTSRYFILNDNSGLLTIK---EGTPPGTYNIKVRVIDGVWPDVVSTV 1893

Query: 881  QLSVRLITEEMLLNSITVRLNDMTAEQFLSPL------LGFFIDGLAAIIPCPKENIYIF 934
            ++ V+ I ++ L N+ ++++ D T E+F+S               L+ II    EN++IF
Sbjct: 1894 KVIVKEIKDDALHNAGSLQIKDTTPEEFISQFPEKESKYNQLKKLLSEIISVQLENVHIF 1953

Query: 935  SVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQV 994
            SV   +   G  ++V F+   P           P+Y    L   V   R  L  +  + +
Sbjct: 1954 SVLKSSQTRG--VDVWFAVYGP-----------PYYKAEKLNGNVAASRAWLENILDINI 2000

Query: 995  LPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQC-PEGFTGV 1053
                 + CV   C +   C++  +  +      + S+    +  ++S  C C       +
Sbjct: 2001 TQIGIDECVTANCTHSSGCISKYEHSHVPTITTAGSISLVSVTVLSSALCSCAARESPHL 2060

Query: 1054 NCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCELRARSFPVS 1113
            +C +  T            C +G  CV   + G  C+ CS  A +    C+    SF   
Sbjct: 2061 SCSSYQTNP----------CLNGGTCV-DTDLGYRCR-CS--ANFHGPDCQQTKHSFKGH 2106

Query: 1114 SFLTFPGLKRRHRIHLKLKFATQTTSGLLLY-----NGRYNERHDFLALELVSSEAGRGG 1168
             +  FP LK      + L+F T+   GLLLY      G+  +  DF+ALEL       GG
Sbjct: 2107 GYAWFPPLKPCFESRISLEFITEVADGLLLYQGPVARGQPGQLEDFIALEL------SGG 2160

Query: 1169 GPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKVLSLAGAADFG 1228
             P L  S S G    +++ + NV D  WH ++I+   + + ++LD C    S+  +    
Sbjct: 2161 VPALTVSHSSGELFLQLSKKVNVADRRWHNIKIKSDGKKVKLVLDHCTNG-SVRHSGSVD 2219

Query: 1229 LKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNI-P-SSFQVKNKDFVGCIS 1286
             K +  + +     +   + T +  R      PLQ+GG+  I P    Q + + FVGCI 
Sbjct: 2220 KKISQVDLS-ACEASEETMGTWSMSRIFSGHQPLQLGGVKKILPYRDSQKRFRGFVGCIR 2278

Query: 1287 DFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSA---PCYNGAECSDLWDTYICDCKEGH 1343
            +  +D K  DL        +  GC      C SA    C     C   W  + CDC  G+
Sbjct: 2279 NVVVDTKVYDLEHPAESLNSSPGCILTDEMCQSAGMVSCGVHGRCVGDWGFFHCDCAPGY 2338

Query: 1344 TGKDCADSTGPPWRFGGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMSIQLKSG--- 1400
             G  C D   P W FG D  + + P      L     L +RTR   + ++S+    G   
Sbjct: 2339 AGPAC-DKVLPEWAFGRDSWIHYEPRNTLSTLSTRIQLMVRTRISRSTLLSLASADGSSF 2397

Query: 1401 ----------LLHYSYNGETMYLPMATL--SDGAWHRIEIKWLGTDISVTVDY--GLRTV 1446
                       +++S  G++  L M TL  ++G W  + ++    + ++ V+   G + V
Sbjct: 2398 IRLEVDEGYFCVNFSLGGKSHSLRMKTLRINNGQWVLLTMERYNNEFTLRVNSGGGDQEV 2457

Query: 1447 LMPMLANKIQGQYIGKILIGGLDTTAGLLASDVGFFEGCIQDVRIGTAQSLL--NRPTV- 1503
               +  ++        +++G       L +     F+GC++DV++   Q LL   R T  
Sbjct: 2458 TSVLGTDRWFEMDWASVVLGN-----RLPSHSESDFQGCLRDVQL-NGQPLLVEGRSTEF 2511

Query: 1504 -----RENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRV----GPQCVSACEL 1554
                 R+ V  GC S A C    C     CV  W    C C AG+V        +  C  
Sbjct: 2512 GFVLRRQGVTMGCHSSA-CSSHPCYSPFLCVDLWRKYECRCPAGKVEVTDNLTGLRHCSS 2570

Query: 1555 GPCGAARCVPDQTPKGYS-----CACEPGY 1579
             PCG   C    T    S     C C  GY
Sbjct: 2571 SPCGHWTCRNGGTCVAQSQHKTICQCPEGY 2600



 Score =  315 bits (774), Expect = 1e-83
 Identities = 262/849 (30%), Positives = 411/849 (48%), Gaps = 82/849 (9%)

Query: 10   QINVL--DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
            QI VL  D ND+ P FE  +Y+  + E    GT+ L + A D D G NA + Y++     
Sbjct: 816  QITVLIADVNDNDPKFENSRYQYFLSEDTPIGTSFLRVTAHDSDQGVNAAITYSM----- 870

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
                              VQ  F+I+  +G +     +   +  R +  + ATD      
Sbjct: 871  --------------LAHQVQ-YFQINPSTGWVYVNHRI--SQTTRISHYIVATD-----G 908

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
               SST  + V I +     P++ +  Y V+V E+ ++ D  ++  IKAT + +G +  +
Sbjct: 909  GNRSSTVELTVTITNALSQPPRWEQSRYWVTVPEN-TIRDTRIVT-IKAT-SPLG-DPRV 964

Query: 188  RYAIIGG-----NTQMQFSI--DSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRS 238
             Y +  G     N  ++F +  +   G  SL+  + LD+E  + + L +RAQ+      +
Sbjct: 965  TYNLEEGQVPETNMPIRFYLRPNRADGSASLLVAEPLDFETTKFFSLTVRAQNVAMIPLA 1024

Query: 239  NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
            + T + +N+ DVNDN P F +S ++ SV E   +G S+V+V A D D G++ ++ Y +  
Sbjct: 1025 SFTIVYVNVTDVNDNVPFFVSSNYEVSVPEGADVGTSVVQVLATDLDSGLHGQVRYFIL- 1083

Query: 299  KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP--------PRSATA 350
            KD + +     TI+P +G + T    DRE +A Y + V + D  +         P + TA
Sbjct: 1084 KDASEDYQF-FTIEPETGIISTHASFDREKRASYLIEVQSQDSSESARPGVHGHPNTDTA 1142

Query: 351  TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNT 408
                           F    YEV + ED   G+PVVT TA D DE  + +L Y+IT GNT
Sbjct: 1143 YVRIFVSDVNDNAPAFPQPVYEVSVDEDRDVGSPVVTATADDRDEGANAKLRYQITSGNT 1202

Query: 409  RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468
            +G F +  +   G + + Q LD+++E+RY L + A+D    + T ++ IN+ + N+ APV
Sbjct: 1203 KGVFDVEPE--AGTVFIVQSLDYEEEQRYELRLVASDGKWENHTLII-INVVNKNDEAPV 1259

Query: 469  FENAPYTASVFED-APIGTTVLVVSATDSDVGINAQ-ITYSLSSEISNEAVAHHDQQFVI 526
            F    Y  S+ E+   +   VL VSATD D   +   ++YSL  + +         +F I
Sbjct: 1260 FTQNEYHGSILEELTDLPVFVLKVSATDPDQEADQNALSYSLHGQGAG-------SEFSI 1312

Query: 527  NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF---KQ 583
            N  TG I+ N+ LDRE  S +   V A D     L+   DV I V D NDN P+F     
Sbjct: 1313 NENTGEISANRRLDREKRSTWRFLVLATDESGEGLTGFADVVIEVRDTNDNAPLFLCVSD 1372

Query: 584  QLYTANIMEDALVGTSVSQVGATDAD---VGLNGRIHYELDPKDREE---GSFVIDPASG 637
              +   + ED+   T+V ++ A D D      +  + Y +    + E     F I+P SG
Sbjct: 1373 DCFMGYVPEDSPADTAVMEMTAVDLDDPKASTHAVLTYRIIQNVQNEINLNLFSINPVSG 1432

Query: 638  VIRT-NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696
             I T   +LDRE V  + L   A DGG    + T    I + D+ND  PVF     T ++
Sbjct: 1433 TICTVLGSLDREKVDKYLLVVEARDGGGLTGTGTAT--ILVTDVNDHAPVFLQRIYTAFV 1490

Query: 697  SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756
            SEN+ I T +  + A D DEG NA+V +SI  GD+   FS+ET +G++   +     +D+
Sbjct: 1491 SENASINTEVAVVSAMDRDEGENAMVTFSILDGDNDCKFSIETDKGNNCGFIHLRKQIDF 1550

Query: 757  ESPRKK-YELVIRAASPPLWNDVRVEILVTDVNDNAPVM-KDFQIIFNNYKDCFPVG-PF 813
            E P ++ + L ++A     ++     I V D ND+APV    F  + +  +D  PVG   
Sbjct: 1551 EKPHERVFNLTLKAEDMDFFSIAHCVIYVEDANDHAPVFYPQFYEVASLAED-VPVGTKV 1609

Query: 814  GRVPAYDAD 822
             +V A D D
Sbjct: 1610 VQVSAVDLD 1618



 Score =  289 bits (709), Expect = 7e-76
 Identities = 253/895 (28%), Positives = 409/895 (45%), Gaps = 80/895 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEA-SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +++ D ND SP F+   Y   ++ E    GT++L + ATD D G N+E+ Y I+  + D 
Sbjct: 501  VHITDENDCSPEFQNSIYSRDNIPETIPIGTSLLQVLATDCDSGSNSEISYFIQ--STD- 557

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSD 128
                                F I  R G + +   L+ E+    Y  +V A D+  P   
Sbjct: 558  --------------------FSIT-RHGVISSNQRLNFERANHMYEFVVIAVDKGHPPR- 595

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
              + TA++ + + + ND  P FS+  Y   + ED     + ++A ++A D D      + 
Sbjct: 596  --TGTASVRIQMANVNDEAPVFSQPVYRTFLSEDAG--PSTLVATVRAKDPD---GDGVL 648

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQD----GGSPSRSNTTQL 243
            Y I GGN +  F +DS  G + L ++     +   Y L I A D    GG    S+  ++
Sbjct: 649  YLIAGGNEEGNFELDSQKGIIKLRRSPAPNLKGPQYILNITAIDDNVSGGPTPLSSFAEV 708

Query: 244  LINIRDVNDNAPRFYTSLFQES---VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
            ++ + D+N+N P F    +      V EN P G  +++V+AYDAD GVN E+ Y +  +D
Sbjct: 709  IVGVNDINNNKPVFRECTYYSDSTWVLENQPPGTYVLQVEAYDADLGVNGEVKYGLMHRD 768

Query: 301  YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
                  L  +ID  +G + T+   DRE Q ++ L VTATD    P               
Sbjct: 769  ---GASLGFSIDSDTGVITTTRSFDREEQKEHTLSVTATDQAPEPLIGICQITVLIADVN 825

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQN 418
                 F   +Y+  L+ED P GT  + +TA D+D+  +  + Y +     +  F I    
Sbjct: 826  DNDPKFENSRYQYFLSEDTPIGTSFLRVTAHDSDQGVNAAITYSMLAHQVQ-YFQINPST 884

Query: 419  GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASV 478
            G   +         Q  R    + ATD G RS T  + + IT+A +  P +E + Y  +V
Sbjct: 885  GWVYVNHR----ISQTTRISHYIVATDGGNRSSTVELTVTITNALSQPPRWEQSRYWVTV 940

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ----TGAIT 534
             E+    T ++ + AT S +G + ++TY+L  E       +   +F + P     + ++ 
Sbjct: 941  PENTIRDTRIVTIKAT-SPLG-DPRVTYNL--EEGQVPETNMPIRFYLRPNRADGSASLL 996

Query: 535  TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
              + LD ET   + LTV A++  +  L+  T V ++V DVNDN P F    Y  ++ E A
Sbjct: 997  VAEPLDFETTKFFSLTVRAQNVAMIPLASFTIVYVNVTDVNDNVPFFVSSNYEVSVPEGA 1056

Query: 595  LVGTSVSQVGATDADVGLNGRIHYELDPKDREEG--SFVIDPASGVIRTNKALDRESVAT 652
             VGTSV QV ATD D GL+G++ Y +  KD  E    F I+P +G+I T+ + DRE  A+
Sbjct: 1057 DVGTSVVQVLATDLDSGLHGQVRYFI-LKDASEDYQFFTIEPETGIISTHASFDREKRAS 1115

Query: 653  HDLKAVAIDGGTP--------PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
            + ++  + D            P + T  V I + D+ND+ P F        + E+  +G+
Sbjct: 1116 YLIEVQSQDSSESARPGVHGHPNTDTAYVRIFVSDVNDNAPAFPQPVYEVSVDEDRDVGS 1175

Query: 705  TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764
             +    A D DEG NA + Y I  G+    F +E   G+    +  +  LDYE   ++YE
Sbjct: 1176 PVVTATADDRDEGANAKLRYQITSGNTKGVFDVEPEAGT----VFIVQSLDYEE-EQRYE 1230

Query: 765  LVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADV 823
            L + A+     N   + I V + ND APV    +   +  ++   +  F  +V A D D 
Sbjct: 1231 LRLVASDGKWENHTLIIINVVNKNDEAPVFTQNEYHGSILEELTDLPVFVLKVSATDPDQ 1290

Query: 824  ---TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE 875
                + L Y +      +   +NE TG ++ + +L+          V  TD   E
Sbjct: 1291 EADQNALSYSLHGQGAGSEFSINENTGEISANRRLDREKRSTWRFLVLATDESGE 1345



 Score =  264 bits (648), Expect = 2e-68
 Identities = 237/812 (29%), Positives = 385/812 (47%), Gaps = 82/812 (10%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I V D ND++P F    YE SV E    G+ V+T  A D+D G NA++ Y  ++ + +T
Sbjct: 1145 RIFVSDVNDNAPAFPQPVYEVSVDEDRDVGSPVVTATADDRDEGANAKLRY--QITSGNT 1202

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                             + VF ++  +G +    SLD E+  RY + + A+D       +
Sbjct: 1203 -----------------KGVFDVEPEAGTVFIVQSLDYEEEQRYELRLVASD------GK 1239

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV-IAKIKATDADVGAN-SAI 187
              +   I +N+++ ND  P F++  Y  S+ E++  TD PV + K+ ATD D  A+ +A+
Sbjct: 1240 WENHTLIIINVVNKNDEAPVFTQNEYHGSILEEL--TDLPVFVLKVSATDPDQEADQNAL 1297

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
             Y++ G     +FSI+  +G++S  + LD E+  ++R ++ A D      +    ++I +
Sbjct: 1298 SYSLHGQGAGSEFSINENTGEISANRRLDREKRSTWRFLVLATDESGEGLTGFADVVIEV 1357

Query: 248  RDVNDNAPRFY---TSLFQESVSENVPIGYSIVRVQAYDADE---GVNAELTYTMTDKDY 301
            RD NDNAP F       F   V E+ P   +++ + A D D+     +A LTY +  ++ 
Sbjct: 1358 RDTNDNAPLFLCVSDDCFMGYVPEDSPADTAVMEMTAVDLDDPKASTHAVLTYRII-QNV 1416

Query: 302  TGNVDLPI-TIDPRSGWVYT-SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
               ++L + +I+P SG + T  G LDRE   KY L+V A DGG    + T T        
Sbjct: 1417 QNEINLNLFSINPVSGTICTVLGSLDREKVDKYLLVVEARDGGG--LTGTGTATILVTDV 1474

Query: 360  XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQ 417
                  F+   Y   ++E+    T V  ++A D DE     + + I  G+   +FSI + 
Sbjct: 1475 NDHAPVFLQRIYTAFVSENASINTEVAVVSAMDRDEGENAMVTFSILDGDNDCKFSIETD 1534

Query: 418  NGR--GLITVAQPLDFKQ--ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAP 473
             G   G I + + +DF++  ER + LT+ A D    S  A   I + DAN++APVF    
Sbjct: 1535 KGNNCGFIHLRKQIDFEKPHERVFNLTLKAEDMDFFS-IAHCVIYVEDANDHAPVFYPQF 1593

Query: 474  Y-TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
            Y  AS+ ED P+GT V+ VSA D D G+N + ++ L ++      +    QF +    G 
Sbjct: 1594 YEVASLAEDVPVGTKVVQVSAVDLDSGLNGRFSFHLLNK------SDPGGQFSV-ASDGW 1646

Query: 533  ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592
            +    +LD ET++ Y L V A D G P L+ +  V +++ DVNDN P F+   Y   + E
Sbjct: 1647 VIVAGVLDHETVTQYQLIVIATDMGQPPLACSATVLVTLQDVNDNGPEFEAH-YNPVVWE 1705

Query: 593  DALVGTSVSQ------VGATDADVGLNGR-IHYELDPKDREEGSFVIDP---ASGVIRTN 642
            +     SV        + A D D   NG    + L       G+F +      S ++   
Sbjct: 1706 NTASPQSVQMNETSTLLYAKDRDTAANGAPFSFHLLSNFDSLGNFHLQDFHNGSALLTAL 1765

Query: 643  KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP-PVFESDCLTFYISENSP 701
               DRE      L  +  D G PP SST  + + I D ND P      +CL +      P
Sbjct: 1766 HTFDREVHKVFHLPILITDSGIPPMSSTNTLTVNIGDQNDHPHSAGYMECLIYSYDGILP 1825

Query: 702  IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761
              T +G++ A D D+    +  +    G  S  F L     +D + L+T+ +    +P  
Sbjct: 1826 T-TVLGQVLAPDGDDWDRKIYQFE---GKTSRYFIL-----NDNSGLLTIKE---GTPPG 1873

Query: 762  KYELVIRAASPPLWNDV--RVEILVTDVNDNA 791
             Y + +R     +W DV   V+++V ++ D+A
Sbjct: 1874 TYNIKVRVID-GVWPDVVSTVKVIVKEIKDDA 1904



 Score =  243 bits (594), Expect = 6e-62
 Identities = 239/817 (29%), Positives = 368/817 (45%), Gaps = 80/817 (9%)

Query: 11   INVLDCNDHSPVF-EMQQYEAS--VREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
            + V D N++ PVF E   Y  S  V E    GT VL ++A D D+G N EV+Y +     
Sbjct: 710  VGVNDINNNKPVFRECTYYSDSTWVLENQPPGTYVLQVEAYDADLGVNGEVKYGL----- 764

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
              ++ + A              F ID  +G + T  S DRE+   +T+ V ATDQA    
Sbjct: 765  --MHRDGASLG-----------FSIDSDTGVITTTRSFDREEQKEHTLSVTATDQA---P 808

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
            + L     I V I D NDN P+F    Y   + ED  +  +    ++ A D+D G N+AI
Sbjct: 809  EPLIGICQITVLIADVNDNDPKFENSRYQYFLSEDTPIGTS--FLRVTAHDSDQGVNAAI 866

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
             Y+++    Q  F I+  +G V +   +      S+ +V  A DGG  +RS+T +L + I
Sbjct: 867  TYSMLAHQVQ-YFQINPSTGWVYVNHRISQTTRISHYIV--ATDGG--NRSSTVELTVTI 921

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
             +     PR+  S +  +V EN      IV ++A  +  G +  +TY + ++      ++
Sbjct: 922  TNALSQPPRWEQSRYWVTVPENTIRDTRIVTIKA-TSPLG-DPRVTYNL-EEGQVPETNM 978

Query: 308  PITIDPR------SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
            PI    R      S  +  +  LD ET   + L V A +    P ++             
Sbjct: 979  PIRFYLRPNRADGSASLLVAEPLDFETTKFFSLTVRAQNVAMIPLASFTIVYVNVTDVND 1038

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNG 419
                F+   YEV + E    GT VV + ATD D     ++ Y I    +      T +  
Sbjct: 1039 NVPFFVSSNYEVSVPEGADVGTSVVQVLATDLDSGLHGQVRYFILKDASEDYQFFTIEPE 1098

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSG----------GRSDTAMVQINITDANNYAPVF 469
             G+I+     D ++   Y++ V + DS             +DTA V+I ++D N+ AP F
Sbjct: 1099 TGIISTHASFDREKRASYLIEVQSQDSSESARPGVHGHPNTDTAYVRIFVSDVNDNAPAF 1158

Query: 470  ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
                Y  SV ED  +G+ V+  +A D D G NA++ Y ++S  + + V      F + P+
Sbjct: 1159 PQPVYEVSVDEDRDVGSPVVTATADDRDEGANAKLRYQITSG-NTKGV------FDVEPE 1211

Query: 530  TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589
             G +   + LD E    Y L + A DG      + T + I+VV+ ND  PVF Q  Y  +
Sbjct: 1212 AGTVFIVQSLDYEEEQRYELRLVASDG---KWENHTLIIINVVNKNDEAPVFTQNEYHGS 1268

Query: 590  IMEDAL-VGTSVSQVGATDADVGLN-GRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647
            I+E+   +   V +V ATD D   +   + Y L  +      F I+  +G I  N+ LDR
Sbjct: 1269 ILEELTDLPVFVLKVSATDPDQEADQNALSYSLHGQG-AGSEFSINENTGEISANRRLDR 1327

Query: 648  ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF---ESDCLTFYISENSPIGT 704
            E  +T     +A D      +    V I++ D ND+ P+F     DC   Y+ E+SP  T
Sbjct: 1328 EKRSTWRFLVLATDESGEGLTGFADVVIEVRDTNDNAPLFLCVSDDCFMGYVPEDSPADT 1387

Query: 705  TIGEIRA---HDPDEGPNAVVHY----SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757
             + E+ A    DP    +AV+ Y    +++   + N FS+    G+       +  LD E
Sbjct: 1388 AVMEMTAVDLDDPKASTHAVLTYRIIQNVQNEINLNLFSINPVSGT---ICTVLGSLDRE 1444

Query: 758  SPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAPV 793
                KY LV+ A     L       ILVTDVND+APV
Sbjct: 1445 KV-DKYLLVVEARDGGGLTGTGTATILVTDVNDHAPV 1480



 Score =  237 bits (581), Expect = 2e-60
 Identities = 233/837 (27%), Positives = 382/837 (45%), Gaps = 82/837 (9%)

Query: 89   VFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
            +F +   SG LL    +D E     Y +L+KA +  S     LSS A + V+I D+ND  
Sbjct: 455  LFTVRQESGELLLTHPVDYEGEHHLYHLLLKAVEAESA----LSSVAEVMVHITDENDCS 510

Query: 148  PQFSEKTYT-VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206
            P+F    Y+  ++ E I +  +  + ++ ATD D G+NS I Y I        FSI +  
Sbjct: 511  PEFQNSIYSRDNIPETIPIGTS--LLQVLATDCDSGSNSEISYFI----QSTDFSI-TRH 563

Query: 207  GDVSLVKTLDYEQV-RSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265
            G +S  + L++E+    Y  V+ A D G P R+ T  + I + +VND AP F   +++  
Sbjct: 564  GVISSNQRLNFERANHMYEFVVIAVDKGHPPRTGTASVRIQMANVNDEAPVFSQPVYRTF 623

Query: 266  VSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV-YTSGQ 323
            +SE+      +  V+A D D +GV     Y +   +  GN +L    D + G +      
Sbjct: 624  LSEDAGPSTLVATVRAKDPDGDGV----LYLIAGGNEEGNFEL----DSQKGIIKLRRSP 675

Query: 324  LDRETQAKYQLLVTATD----GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE---LA 376
                   +Y L +TA D    GG  P S+ A               F    Y  +   + 
Sbjct: 676  APNLKGPQYILNITAIDDNVSGGPTPLSSFAEVIVGVNDINNNKPVFRECTYYSDSTWVL 735

Query: 377  EDEPPGTPVVTLTATDAD--EDNRLHYEI--TGGNTRGRFSITSQNGRGLITVAQPLDFK 432
            E++PPGT V+ + A DAD   +  + Y +    G + G FSI S    G+IT  +  D +
Sbjct: 736  ENQPPGTYVLQVEAYDADLGVNGEVKYGLMHRDGASLG-FSIDSDT--GVITTTRSFDRE 792

Query: 433  QERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
            +++ + L+V+ATD        + QI   I D N+  P FEN+ Y   + ED PIGT+ L 
Sbjct: 793  EQKEHTLSVTATDQAPEPLIGICQITVLIADVNDNDPKFENSRYQYFLSEDTPIGTSFLR 852

Query: 491  VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550
            V+A DSD G+NA ITYS+        +AH  Q F INP TG +  N  + + T   + + 
Sbjct: 853  VTAHDSDQGVNAAITYSM--------LAHQVQYFQINPSTGWVYVNHRISQTTRISHYIV 904

Query: 551  VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610
             T  DGG  + S T ++ +++ +     P ++Q  Y   + E+ +  T +  + AT + +
Sbjct: 905  AT--DGG--NRSSTVELTVTITNALSQPPRWEQSRYWVTVPENTIRDTRIVTIKAT-SPL 959

Query: 611  GLNGRIHYELD----PKDREEGSFVIDP----ASGVIRTNKALDRESVATHDLKAVAIDG 662
            G + R+ Y L+    P+      F + P     S  +   + LD E+     L   A + 
Sbjct: 960  G-DPRVTYNLEEGQVPETNMPIRFYLRPNRADGSASLLVAEPLDFETTKFFSLTVRAQNV 1018

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
               P +S  IV++ + D+ND+ P F S      + E + +GT++ ++ A D D G +  V
Sbjct: 1019 AMIPLASFTIVYVNVTDVNDNVPFFVSSNYEVSVPEGADVGTSVVQVLATDLDSGLHGQV 1078

Query: 723  HYSI--KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR------AASP-- 772
             Y I     +D   F++E   G     + T    D E  R  Y + ++      +A P  
Sbjct: 1079 RYFILKDASEDYQFFTIEPETGI----ISTHASFDREK-RASYLIEVQSQDSSESARPGV 1133

Query: 773  ---PLWNDVRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPAYDADVTDKL 827
               P  +   V I V+DVNDNAP      +++  +  +D             D     KL
Sbjct: 1134 HGHPNTDTAYVRIFVSDVNDNAPAFPQPVYEVSVDEDRDVGSPVVTATADDRDEGANAKL 1193

Query: 828  QYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884
            +Y+I SGN   +  +    G++ +   L+    +   + +  +DG  E   ++ ++V
Sbjct: 1194 RYQITSGNTKGVFDVEPEAGTVFIVQSLDYEEEQRYELRLVASDGKWENHTLIIINV 1250



 Score =  185 bits (450), Expect = 2e-44
 Identities = 169/606 (27%), Positives = 276/606 (45%), Gaps = 48/606 (7%)

Query: 137 HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA-IRYAIIGGN 195
           HV ++   +    ++   Y      D       ++ ++ A  ++    SA + Y +I G 
Sbjct: 297 HVTLLAPEEELLSWAMYPYPYLARVDPDARKGTLVYRLAARYSNSENTSAGVSYTLIAGG 356

Query: 196 TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG-GSPSRSNTTQLLINIRDVNDNA 254
            + +F +D  +G + +   L     + Y + ++A D  G+ S   +  +L+  R      
Sbjct: 357 EE-RFQVDVDTG-IIVTTGLPLVWNKEYVVTVQASDEYGNKSPFASISILVGSRP----- 409

Query: 255 PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR 314
           P+F    +   V EN P G  +  V+A       +  L+Y++       N     T+   
Sbjct: 410 PQFTNMSYSVFVPENTPPGEKVAVVEAVSFQ---SQPLSYSLLT-----NPSGLFTVRQE 461

Query: 315 SGWVYTSGQLDRETQAK-YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373
           SG +  +  +D E +   Y LL+ A +  +   S+ A               F    Y  
Sbjct: 462 SGELLLTHPVDYEGEHHLYHLLLKAVEA-ESALSSVAEVMVHITDENDCSPEFQNSIYSR 520

Query: 374 E-LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432
           + + E  P GT ++ + ATD D  +  + EI+       FSIT     G+I+  Q L+F+
Sbjct: 521 DNIPETIPIGTSLLQVLATDCDSGS--NSEISYFIQSTDFSITRH---GVISSNQRLNFE 575

Query: 433 QERR-YVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
           +    Y   V A D G   R+ TA V+I + + N+ APVF    Y   + EDA   T V 
Sbjct: 576 RANHMYEFVVIAVDKGHPPRTGTASVRIQMANVNDEAPVFSQPVYRTFLSEDAGPSTLVA 635

Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG--Y 547
            V A D D      + Y ++    NE     +  F ++ Q G I   +      + G  Y
Sbjct: 636 TVRAKDPD---GDGVLYLIAG--GNE-----EGNFELDSQKGIIKLRRS-PAPNLKGPQY 684

Query: 548 LLTVTARD----GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN---IMEDALVGTSV 600
           +L +TA D    GG   LS   +V + V D+N+N+PVF++  Y ++   ++E+   GT V
Sbjct: 685 ILNITAIDDNVSGGPTPLSSFAEVIVGVNDINNNKPVFRECTYYSDSTWVLENQPPGTYV 744

Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
            QV A DAD+G+NG + Y L  +D     F ID  +GVI T ++ DRE    H L   A 
Sbjct: 745 LQVEAYDADLGVNGEVKYGLMHRDGASLGFSIDSDTGVITTTRSFDREEQKEHTLSVTAT 804

Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
           D    P      + + I D+ND+ P FE+    +++SE++PIGT+   + AHD D+G NA
Sbjct: 805 DQAPEPLIGICQITVLIADVNDNDPKFENSRYQYFLSEDTPIGTSFLRVTAHDSDQGVNA 864

Query: 721 VVHYSI 726
            + YS+
Sbjct: 865 AITYSM 870



 Score = 83.8 bits (198), Expect = 6e-14
 Identities = 113/411 (27%), Positives = 174/411 (42%), Gaps = 39/411 (9%)

Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
           PY A V  DA  GT V  ++A  S    N++ T   S+ +S   +A  +++F ++  TG 
Sbjct: 316 PYLARVDPDARKGTLVYRLAARYS----NSENT---SAGVSYTLIAGGEERFQVDVDTGI 368

Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592
           I T  L        Y++TV A D      + +    IS++ V    P F    Y+  + E
Sbjct: 369 IVTTGL-PLVWNKEYVVTVQASD---EYGNKSPFASISIL-VGSRPPQFTNMSYSVFVPE 423

Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA- 651
           +   G  V+ V A       +  + Y L       G F +   SG +     +D E    
Sbjct: 424 NTPPGEKVAVVEAVSFQ---SQPLSYSL--LTNPSGLFTVRQESGELLLTHPVDYEGEHH 478

Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF-YISENSPIGTTIGEIR 710
            + L   A++  +   SS   V + I D ND  P F++   +   I E  PIGT++ ++ 
Sbjct: 479 LYHLLLKAVEAESA-LSSVAEVMVHITDENDCSPEFQNSIYSRDNIPETIPIGTSLLQVL 537

Query: 711 AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770
           A D D G N+ + Y I+    S  FS+ TR G     + +   L++E     YE V+ A 
Sbjct: 538 ATDCDSGSNSEISYFIQ----STDFSI-TRHG----VISSNQRLNFERANHMYEFVVIAV 588

Query: 771 S---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY--KDCFPVGPFGRVPAYDADVTD 825
               PP      V I + +VND APV    Q ++  +  +D  P      V A D D  D
Sbjct: 589 DKGHPPRTGTASVRIQMANVNDEAPVFS--QPVYRTFLSEDAGPSTLVATVRAKDPD-GD 645

Query: 826 KLQYRILSGNNANLILLNETTGSMTL--SPQLNTNVPKLATMEVSVTDGVN 874
            + Y I  GN      L+   G + L  SP  N   P+      ++ D V+
Sbjct: 646 GVLYLIAGGNEEGNFELDSQKGIIKLRRSPAPNLKGPQYILNITAIDDNVS 696



 Score = 83.8 bits (198), Expect = 6e-14
 Identities = 82/257 (31%), Positives = 114/257 (44%), Gaps = 35/257 (13%)

Query: 8    HQQINVLDCNDHSPVFEMQQYE-ASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            H  I V D NDH+PVF  Q YE AS+ E    GT V+ + A D D G N    + +    
Sbjct: 1574 HCVIYVEDANDHAPVFYPQFYEVASLAEDVPVGTKVVQVSAVDLDSGLNGRFSFHL---- 1629

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
               LN  D               F +    G ++    LD E V +Y ++V ATD   P 
Sbjct: 1630 ---LNKSDPGGQ-----------FSV-ASDGWVIVAGVLDHETVTQYQLIVIATDMGQP- 1673

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI----SVTDNPVIAKIKATDADVG 182
               L+ +AT+ V + D NDN P+F E  Y   V E+     SV  N     + A D D  
Sbjct: 1674 --PLACSATVLVTLQDVNDNGPEF-EAHYNPVVWENTASPQSVQMNETSTLLYAKDRDTA 1730

Query: 183  ANSA-IRYAIIG-----GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS 236
            AN A   + ++      GN  +Q    + S  ++ + T D E  + + L I   D G P 
Sbjct: 1731 ANGAPFSFHLLSNFDSLGNFHLQ-DFHNGSALLTALHTFDREVHKVFHLPILITDSGIPP 1789

Query: 237  RSNTTQLLINIRDVNDN 253
             S+T  L +NI D ND+
Sbjct: 1790 MSSTNTLTVNIGDQNDH 1806



 Score = 42.3 bits (95), Expect = 0.19
 Identities = 31/94 (32%), Positives = 46/94 (48%), Gaps = 5/94 (5%)

Query: 695 YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV--TMV 752
           ++ E+SP GT +  +R   P  GP          GD ++ FSL+ R G ++  L   T  
Sbjct: 32  HVPEDSPAGTRVRGVRV--PLRGPGEPPARWALRGDGAHHFSLQRRPGGERGALEARTAR 89

Query: 753 DLDYESPRKKYELVIRAASPPLWNDVRVEILVTD 786
            LD    R +Y L++RAA  P    +RV +L  D
Sbjct: 90  RLD-RGARAEYRLLLRAAVRPRAALLRVRVLARD 122


>UniRef50_UPI00015B6261 Cluster: PREDICTED: similar to CG7749-PA; n=1;
            Nasonia vitripennis|Rep: PREDICTED: similar to CG7749-PA
            - Nasonia vitripennis
          Length = 4840

 Score =  462 bits (1139), Expect = e-128
 Identities = 400/1400 (28%), Positives = 640/1400 (45%), Gaps = 131/1400 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + VLD NDH+P FE   Y  +V E    GT++L + A D D+G N EV Y+      +  
Sbjct: 2889 LQVLDENDHAPKFESNPYSIAVAENIEEGTSILKVVAHDNDLGSNGEVRYSFGSDIGELA 2948

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N                 VF ID  +G + +   LD+E+   Y   V ATD  +P   R 
Sbjct: 2949 N-----------------VFTIDAYTGWISSLVQLDKEQQPEYKFQVIATDNGNP---RH 2988

Query: 131  SSTATIHVNIIDDNDNYPQFS--EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             S  ++ V + D NDN   FS  E  Y  +V ED       V+ ++   D D   N+A+ 
Sbjct: 2989 FSRTSVLVKLKDYNDNPSAFSSAESGYQATVKED--ALPGTVVVELTTVDKDTELNTALD 3046

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            + II G+ + QF+I S +G V + K LD E    Y L++   DG        T++++ + 
Sbjct: 3047 FYIISGDPRSQFAIRS-TGQVYVAKALDRETRDRYELLVVGTDGKFVFE---TRVIVQVL 3102

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            DVNDN P      ++E +SE    G  ++ V A D D+  NA+L + +T     G  +  
Sbjct: 3103 DVNDNPPYCLKYRYREVLSEGSHPGSYVLTVLATDYDDEPNAKLRFYLT-----GGKNEK 3157

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
             ++D  +G + T GQLDRE+QAKY L     D        ++               F  
Sbjct: 3158 FSLDKETGVLKTVGQLDRESQAKYILTAHVQDRDKTSWECSSQLEILISDLNDNAPRFSM 3217

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
              Y   L ED   GT V  + ATD D   + ++ YE    +    F I+  +G  ++T+A
Sbjct: 3218 QSYSATLPEDVEVGTLVTKVHATDDDIGINRKIRYEFLD-SANDHFVISPDSG--IVTLA 3274

Query: 427  QPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
            +PLD + +  Y +++ A D G    S    + +N+ D N+  P F +  Y A V E   +
Sbjct: 3275 KPLDRETKAMYNVSIQAMDQGTPQLSSVTFLIVNVQDINDNPPEFTSKYYFARVPEIDAV 3334

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            GT V  V AT  D G+NA + Y++     NE      ++F I+ ++G ++  + LD E  
Sbjct: 3335 GTEVARVLATSKDTGVNADVYYTIVG--GNE-----HKKFEIDTKSGVVSIAEQLDYERA 3387

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
              Y LT+ A DGGVP L++   V I+V+D NDN P+F Q  Y A+I EDA  G  V QV 
Sbjct: 3388 KDYFLTIQAIDGGVPPLTNHATVNITVLDSNDNAPMFSQASYRASIREDAKAGEKVVQVF 3447

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            A D D   NG++ Y ++  DR++  F ID  SG I     LDRE +A++ L+  A D G 
Sbjct: 3448 ANDLDSNENGQVSYSIERGDRQK-QFTIDSQSGQITVLAPLDREQIASYVLEVHAKDNGI 3506

Query: 665  PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH- 723
            P  S+ VIV+I++ D ND+PP+F  +  T  + E+ P+G  + +    D D  PNA  + 
Sbjct: 3507 PTLSNYVIVNIEVIDANDNPPLFAQNNYTTVVQEDKPLGYAVLKFTVTDADAEPNAAPYT 3566

Query: 724  YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRV 780
            +  + G++ ++F LE + G+    L T         + KY L IR     SPPL++D  V
Sbjct: 3567 FDFRSGNEGDAFRLE-QDGT----LRTATKFS-NRVKDKYLLHIRVFDNGSPPLYSDAWV 3620

Query: 781  EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRIL----SGNN 836
             + + + +   PV+   +I  N+Y D +P G  G+V A D D  D LQY ++    S  N
Sbjct: 3621 LVKIIEESQYPPVITLLEININSYMDEYPGGVIGKVHASDKDQYDTLQYSLVPTSPSRPN 3680

Query: 837  ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSI 896
             +L  +++  G++   P+L+    +   + VSVTDG      +++++V L+T+ ML NS+
Sbjct: 3681 TDLFQIDKLDGTLVALPRLDIGEYR---VNVSVTDGKFNSYTIVKVTVELVTDTMLENSV 3737

Query: 897  TVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILN---VSFSA 953
             VR  +++ E F+      F+  +   + C  +++ I SVQ  TD   N++    V  + 
Sbjct: 3738 IVRFREVSPEDFVLKHRKGFVRTVRNAMNCRLKDVVILSVQPSTDAEINVIKSRPVRQAV 3797

Query: 954  RRPDAEVGVA---GDPSPHYSPTHLRERVYLHRTTL---ARLATVQVLPF--DDNICVHE 1005
               D +V       DP   Y+   +RE +  H   L    +L   +++ F      CV+ 
Sbjct: 3798 VHNDLDVLFTVKKPDPGEFYTSEAIREALNQHIEELEASTKLVVEEIVRFKCSKGYCVYG 3857

Query: 1006 PCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKAS-- 1063
             C +      VL     +      +    P +   +  C C EG+ G +CE ++ + +  
Sbjct: 3858 ECHD----KIVLDSQQITPIATDVTSFVSPRHRHRT-ECSCKEGYAGTHCEIVINECARG 3912

Query: 1064 -CEV----DGDGSICRSGSQCVARREGGILCQGCSIDAAYT-TAVCELRAR--SFPVSSF 1115
             C V      D S+     QC      G   Q C ID +      C +     SF   S+
Sbjct: 3913 PCPVFKVCIPDSSVQGYSCQC----PEGFAGQTCDIDISKCHDESCYIPRNPISFSGKSY 3968

Query: 1116 LTF---PGLKRR---HRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRGGG 1169
              +     L R+   +++ L L+  +   +G L+Y      + D+  LE+V+        
Sbjct: 3969 ARYKIDKSLVRQTIENQLSLSLRIRSVQPTGNLMYAA---GKVDYNVLEIVNG------- 4018

Query: 1170 PGLRFSFSLGGGKSEITVEG-NVGDGSWHTVEIEYFNRTITMILDDCDKVLSLAGAADFG 1228
              +++ F LG G+  + V    + DG WH +++E  + + T+ +D   K L+   A    
Sbjct: 4019 -AVQYRFDLGSGEGLVRVNSFYISDGQWHEIQLERESNSATLTVD--GKHLAHGSAPGVN 4075

Query: 1229 LKYACANFTRKVLPARCEIPTE-TCHRFLDLTGPLQIGGLPNIPSSFQVKNKDFVGCISD 1287
                  N     L    E+ +  +   F D+     +G + ++  +         G  S 
Sbjct: 4076 ---DILNLQSDDLYLGAEVRSHPSIIGFEDVQRGF-VGCMDDVRIAKVSVPLHMSGSTSS 4131

Query: 1288 FYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDT---YICDCKEGHT 1344
              +  +F ++  +  +  T+   P     C S PC NG  CS+       Y C C     
Sbjct: 4132 LVVLKRFANV-EFSCEASTVLTPP---GVCGSQPCQNGGTCSESKTEDGGYECQCHNRFR 4187

Query: 1345 GKDCADSTGP----PWRFGG 1360
            G  C   T P    P  +GG
Sbjct: 4188 GASCEIDTDPCASSPCLYGG 4207



 Score =  364 bits (896), Expect = 2e-98
 Identities = 265/890 (29%), Positives = 436/890 (48%), Gaps = 59/890 (6%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ V D ND+SPVF +++Y+AS+    +  +  L +KA D D G  A++ Y+I       
Sbjct: 2678 RVKVTDENDNSPVFLLKEYKASIYGNLTLNSAFLKVKALDADEGDAAKIIYSI------- 2730

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
              P+++          ++++F I+  +GA+  + S    +   + + V+A D+    S  
Sbjct: 2731 FEPQNSE---------IKNIFGINPDTGAVFLKKSAKPWETQPFQLFVRAQDKGL-ASHH 2780

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            +     + + I+   D  P F  K     V E  S    P+      T+     NS +  
Sbjct: 2781 VD--VPVEIYIMGPEDIPPLFERKEDKFFVSET-STIGTPITRLRTVTNT----NSTVTC 2833

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             ++       F++D  +  V+L   LD E   SY + + A+   SP  +   ++ + + D
Sbjct: 2834 RLVSAGDDFPFAVDPKTCRVTLSGNLDREVKDSYMIGVLAETDSSPPLTALAEITLQVLD 2893

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM-TDKDYTGNVDLP 308
             ND+AP+F ++ +  +V+EN+  G SI++V A+D D G N E+ Y+  +D     NV   
Sbjct: 2894 ENDHAPKFESNPYSIAVAENIEEGTSILKVVAHDNDLGSNGEVRYSFGSDIGELANV--- 2950

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
             TID  +GW+ +  QLD+E Q +Y+  V ATD G+P   +  +              F  
Sbjct: 2951 FTIDAYTGWISSLVQLDKEQQPEYKFQVIATDNGNPRHFSRTSVLVKLKDYNDNPSAFSS 3010

Query: 369  GQ--YEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLIT 424
             +  Y+  + ED  PGT VV LT  D D +    L + I  G+ R +F+I S    G + 
Sbjct: 3011 AESGYQATVKEDALPGTVVVELTTVDKDTELNTALDFYIISGDPRSQFAIRST---GQVY 3067

Query: 425  VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
            VA+ LD +   RY L V  TD     +T ++ + + D N+  P      Y   + E +  
Sbjct: 3068 VAKALDRETRDRYELLVVGTDGKFVFETRVI-VQVLDVNDNPPYCLKYRYREVLSEGSHP 3126

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            G+ VL V ATD D   NA++ + L+           +++F ++ +TG + T   LDRE+ 
Sbjct: 3127 GSYVLTVLATDYDDEPNAKLRFYLTGG--------KNEKFSLDKETGVLKTVGQLDRESQ 3178

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
            + Y+LT   +D    S   ++ +EI + D+NDN P F  Q Y+A + ED  VGT V++V 
Sbjct: 3179 AKYILTAHVQDRDKTSWECSSQLEILISDLNDNAPRFSMQSYSATLPEDVEVGTLVTKVH 3238

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            ATD D+G+N +I YE    D     FVI P SG++   K LDRE+ A +++   A+D GT
Sbjct: 3239 ATDDDIGINRKIRYEF--LDSANDHFVISPDSGIVTLAKPLDRETKAMYNVSIQAMDQGT 3296

Query: 665  PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
            P  SS   + + ++DIND+PP F S      + E   +GT +  + A   D G NA V+Y
Sbjct: 3297 PQLSSVTFLIVNVQDINDNPPEFTSKYYFARVPEIDAVGTEVARVLATSKDTGVNADVYY 3356

Query: 725  SIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVIRAAS---PPLWNDVRV 780
            +I GG++   F ++T+ G     +V++ + LDYE   K Y L I+A     PPL N   V
Sbjct: 3357 TIVGGNEHKKFEIDTKSG-----VVSIAEQLDYER-AKDYFLTIQAIDGGVPPLTNHATV 3410

Query: 781  EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGNNAN 838
             I V D NDNAP+        +  +D        +V A D D  +  ++ Y I  G+   
Sbjct: 3411 NITVLDSNDNAPMFSQASYRASIREDAKAGEKVVQVFANDLDSNENGQVSYSIERGDRQK 3470

Query: 839  LILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLI 887
               ++  +G +T+   L+        +EV   D G+  +   + +++ +I
Sbjct: 3471 QFTIDSQSGQITVLAPLDREQIASYVLEVHAKDNGIPTLSNYVIVNIEVI 3520



 Score =  311 bits (763), Expect = 2e-82
 Identities = 250/881 (28%), Positives = 417/881 (47%), Gaps = 77/881 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +++V D ND++P F +  Y   VRE     + +  ++ATD D G    +EY+     ++ 
Sbjct: 1002 RVSVDDVNDNAPKFALTSYTVKVREDVPVWSVIAVIEATDPDEGPGGIIEYSF----SEE 1057

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            +  E                F ID  SG + +   LD E+   +T+ + A D+  P    
Sbjct: 1058 MESE--------------GFFGIDKLSGTIRSLQKLDFEERQVHTLTIVAKDKGEP---S 1100

Query: 130  LSSTATIHVNIIDDNDNY--PQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSA 186
            LSS   + + ++D N+N   P F++   + SV E+  +  N ++ ++KA DAD  G +S 
Sbjct: 1101 LSSETILIIEVVDVNENLHAPVFNDFVISASVSENQPL--NTLVTQVKAKDADPPGGDSR 1158

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            I Y+I GG+    FSID   G++     LD E    Y L + AQD G    S+  Q+ + 
Sbjct: 1159 IGYSIRGGDGVGLFSIDD-EGNIRTKAVLDVEAKAGYWLTVYAQDHGVVPLSSKLQVYVE 1217

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            + D NDN P     ++  SV EN P G S+++++A+D D     + ++ +T    +GN +
Sbjct: 1218 VLDENDNTPLTEQPVYYPSVLENSPAGVSVLQIRAFDRDVSPQ-QFSFAIT----SGNAE 1272

Query: 307  LPITIDPRSGWVYTSG-QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
                I+  SG + TSG +LDRE QA++ L VT  D G P  S+T                
Sbjct: 1273 GYFLINSTSGLITTSGRKLDRENQAEHILEVTVRDDGRPVLSSTTRVVVQVDDVNDHSPV 1332

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLI 423
            F    Y V++        P+  + A D D  ++ ++ Y I  G  +G+F I    G    
Sbjct: 1333 FEEKFYMVQIPASPSLDKPLFQVLAHDQDIGKNGKIQYSIKSGKGKGKFKIHPDTG---- 1388

Query: 424  TVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDA---NNYAPVFENAPYTASV 478
             V     F+  + + + + ATD G   RS  A + + + +    +   PVF++   +  V
Sbjct: 1389 MVYSQRGFEAGQEFEMIIRATDEGEPPRSHQARISVQVVETPKDSPNPPVFKSLNQSVEV 1448

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             E    G  V ++ ATD D      + Y +    + +       +FVI    G +   K 
Sbjct: 1449 TESDKAGFLVALMQATDKD---GDSLWYDIVEGDTRD-------EFVIGRDDGNVLLAKQ 1498

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL-VG 597
            LD ET + Y LT++  DG   +    T + + V+D+ND+ P   + +Y   I E+ +  G
Sbjct: 1499 LDWETQNFYNLTISVTDGVNEA---RTSLFVKVIDINDHRPELSESIYHVEISENVVEKG 1555

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREEG--SFVIDPASGVIRTNKALDRESVATHDL 655
             ++ Q+ A D D   + ++ Y L     +     F +D  +G I  N+ALDRE++  H L
Sbjct: 1556 EAILQLHAQDLDE--DKKLFYSLHNAQSQASLQIFHVDSLTGTITLNEALDRETIQEHIL 1613

Query: 656  KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
              +  D GTP + +   V + + D ND  P F S+ +   + E SPIGT + ++ A D D
Sbjct: 1614 TVMVKDQGTPAKRNFARVLVTVHDHNDHAPTFISEIIQGKVFETSPIGTAVVQVIAIDRD 1673

Query: 716  EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASP 772
             G NA + YS+  G+  N FS++   G+    +   +DL   +   +Y L+++A    SP
Sbjct: 1674 RGENAQLSYSMTSGNVGNVFSIDPDLGT--IRVARELDL---ATASEYILLVKATDHGSP 1728

Query: 773  PLWNDVRVEILVTDVNDNAP---VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQY 829
             L N + V ++VT + DNAP   V    ++    Y++   +G F  V   +A  T  LQ+
Sbjct: 1729 ALSNSIPVHVMVT-MADNAPPRFVRSGAELAAEIYEN-EEIGSF--VKHIEARSTSSLQF 1784

Query: 830  RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVT 870
             I+SGN      +N +TG ++   +L+    K   + ++ T
Sbjct: 1785 EIVSGNIGEAFFINPSTGVISTQERLDYEDVKFYNLSIAAT 1825



 Score =  307 bits (753), Expect = 3e-81
 Identities = 236/768 (30%), Positives = 370/768 (48%), Gaps = 54/768 (7%)

Query: 143  DNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI 202
            +N + P+F +    + V+E   +    V+A++ A D D+G N  + Y I  G++   F I
Sbjct: 789  ENVHAPEFLDFPNEIRVNESAPI--GFVLARLAARDRDLGYNGKLVYGISAGDSDSVFGI 846

Query: 203  DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLF 262
            D  +G++ L+  LD E+   Y L I   D G P +S +  L +++ DVNDNAP+F  +L 
Sbjct: 847  DPDTGELRLIGRLDREREDEYFLNITVYDLGKPQKSASRMLAVSVLDVNDNAPKFEKALA 906

Query: 263  QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322
               VSE    G  I R    DAD G NA++ Y++     T   D    +D  +G +   G
Sbjct: 907  SFRVSEAALNGTIIFRANTTDADLGENAQVAYSLV----TDTSD--FRVDRTTGVLTVFG 960

Query: 323  QLDRETQAKYQLLVTATD--GG---------DPPRSATATXXXXXXXXXXXXXXFMPGQY 371
            +LDRE Q+ Y+L + ATD  GG         +P   + A               F    Y
Sbjct: 961  KLDRERQSSYELRIRATDKNGGNDKGEPDFDNPALYSEALVRVSVDDVNDNAPKFALTSY 1020

Query: 372  EVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGG-NTRGRFSITSQNGRGLITVAQP 428
             V++ ED P  + +  + ATD DE     + Y  +    + G F I   +  G I   Q 
Sbjct: 1021 TVKVREDVPVWSVIAVIEATDPDEGPGGIIEYSFSEEMESEGFFGIDKLS--GTIRSLQK 1078

Query: 429  LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANN--YAPVFENAPYTASVFEDAPI 484
            LDF++ + + LT+ A D G    S   ++ I + D N   +APVF +   +ASV E+ P+
Sbjct: 1079 LDFEERQVHTLTIVAKDKGEPSLSSETILIIEVVDVNENLHAPVFNDFVISASVSENQPL 1138

Query: 485  GTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
             T V  V A D+D  G +++I YS+      + V      F I+ + G I T  +LD E 
Sbjct: 1139 NTLVTQVKAKDADPPGGDSRIGYSIR---GGDGVG----LFSIDDE-GNIRTKAVLDVEA 1190

Query: 544  MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
             +GY LTV A+D GV  LS    V + V+D NDN P+ +Q +Y  +++E++  G SV Q+
Sbjct: 1191 KAGYWLTVYAQDHGVVPLSSKLQVYVEVLDENDNTPLTEQPVYYPSVLENSPAGVSVLQI 1250

Query: 604  GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN-KALDRESVATHDLKAVAIDG 662
             A D DV    +  + +      EG F+I+  SG+I T+ + LDRE+ A H L+    D 
Sbjct: 1251 RAFDRDVSPQ-QFSFAI-TSGNAEGYFLINSTSGLITTSGRKLDRENQAEHILEVTVRDD 1308

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
            G P  SST  V ++++D+ND  PVFE       I  +  +   + ++ AHD D G N  +
Sbjct: 1309 GRPVLSSTTRVVVQVDDVNDHSPVFEEKFYMVQIPASPSLDKPLFQVLAHDQDIGKNGKI 1368

Query: 723  HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVR 779
             YSIK G     F +    G      +      +E+  +++E++IRA     PP  +  R
Sbjct: 1369 QYSIKSGKGKGKFKIHPDTG------MVYSQRGFEA-GQEFEMIIRATDEGEPPRSHQAR 1421

Query: 780  VEILVTDV---NDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNN 836
            + + V +    + N PV K         +          + A D D  D L Y I+ G+ 
Sbjct: 1422 ISVQVVETPKDSPNPPVFKSLNQSVEVTESDKAGFLVALMQATDKD-GDSLWYDIVEGDT 1480

Query: 837  ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884
             +  ++    G++ L+ QL+        + +SVTDGVNE +  + + V
Sbjct: 1481 RDEFVIGRDDGNVLLAKQLDWETQNFYNLTISVTDGVNEARTSLFVKV 1528



 Score =  293 bits (718), Expect = 6e-77
 Identities = 261/886 (29%), Positives = 406/886 (45%), Gaps = 75/886 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            ++VLD ND++P FE       V E A +GT +     TD D+G+NA+V Y++   T+D  
Sbjct: 889  VSVLDVNDNAPKFEKALASFRVSEAALNGTIIFRANTTDADLGENAQVAYSLVTDTSD-- 946

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ------AS 124
                               FR+D  +G L     LDRE+ + Y + ++ATD+        
Sbjct: 947  -------------------FRVDRTTGVLTVFGKLDRERQSSYELRIRATDKNGGNDKGE 987

Query: 125  PVSDR--LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
            P  D   L S A + V++ D NDN P+F+  +YTV V ED+ V    VIA I+ATD D G
Sbjct: 988  PDFDNPALYSEALVRVSVDDVNDNAPKFALTSYTVKVREDVPVWS--VIAVIEATDPDEG 1045

Query: 183  ANSAIRYAIIGG-NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
                I Y+      ++  F ID LSG +  ++ LD+E+ + + L I A+D G PS S+ T
Sbjct: 1046 PGGIIEYSFSEEMESEGFFGIDKLSGTIRSLQKLDFEERQVHTLTIVAKDKGEPSLSSET 1105

Query: 242  QLLINIRDVNDN--APRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTD 298
             L+I + DVN+N  AP F   +   SVSEN P+   + +V+A DAD  G ++ + Y++  
Sbjct: 1106 ILIIEVVDVNENLHAPVFNDFVISASVSENQPLNTLVTQVKAKDADPPGGDSRIGYSIRG 1165

Query: 299  KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358
             D  G      +ID   G + T   LD E +A Y L V A D G  P S+          
Sbjct: 1166 GDGVG----LFSIDD-EGNIRTKAVLDVEAKAGYWLTVYAQDHGVVPLSSKLQVYVEVLD 1220

Query: 359  XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD-EDNRLHYEITGGNTRGRFSITSQ 417
                        Y   + E+ P G  V+ + A D D    +  + IT GN  G F I S 
Sbjct: 1221 ENDNTPLTEQPVYYPSVLENSPAGVSVLQIRAFDRDVSPQQFSFAITSGNAEGYFLINST 1280

Query: 418  NGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYT 475
            +G  + T  + LD + +  ++L V+  D G    S T  V + + D N+++PVFE   Y 
Sbjct: 1281 SGL-ITTSGRKLDRENQAEHILEVTVRDDGRPVLSSTTRVVVQVDDVNDHSPVFEEKFYM 1339

Query: 476  ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
              +     +   +  V A D D+G N +I YS+ S            +F I+P TG + +
Sbjct: 1340 VQIPASPSLDKPLFQVLAHDQDIGKNGKIQYSIKS-------GKGKGKFKIHPDTGMVYS 1392

Query: 536  NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV---NDNEPVFKQQLYTANIME 592
             +    E    + + + A D G P  S    + + VV+    + N PVFK    +  + E
Sbjct: 1393 QR--GFEAGQEFEMIIRATDEGEPPRSHQARISVQVVETPKDSPNPPVFKSLNQSVEVTE 1450

Query: 593  DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652
                G  V+ + ATD D      + Y++   D  +  FVI    G +   K LD E+   
Sbjct: 1451 SDKAGFLVALMQATDKD---GDSLWYDIVEGDTRD-EFVIGRDDGNVLLAKQLDWETQNF 1506

Query: 653  HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN-SPIGTTIGEIRA 711
            ++L     DG    ++S   + +K+ DIND  P          ISEN    G  I ++ A
Sbjct: 1507 YNLTISVTDGVNEARTS---LFVKVIDINDHRPELSESIYHVEISENVVEKGEAILQLHA 1563

Query: 712  HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKY--ELVIR 768
             D DE  +  + YS+      +  SL+          +T+ + LD E+ ++     +V  
Sbjct: 1564 QDLDE--DKKLFYSLHNA--QSQASLQIFHVDSLTGTITLNEALDRETIQEHILTVMVKD 1619

Query: 769  AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTD-- 825
              +P   N  RV + V D ND+AP     +II     +  P+G    +V A D D  +  
Sbjct: 1620 QGTPAKRNFARVLVTVHDHNDHAPTFIS-EIIQGKVFETSPIGTAVVQVIAIDRDRGENA 1678

Query: 826  KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            +L Y + SGN  N+  ++   G++ ++ +L+        + V  TD
Sbjct: 1679 QLSYSMTSGNVGNVFSIDPDLGTIRVARELDLATASEYILLVKATD 1724



 Score =  291 bits (714), Expect = 2e-76
 Identities = 253/883 (28%), Positives = 418/883 (47%), Gaps = 81/883 (9%)

Query: 17   NDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAX 76
            N H+P F     E  V E A  G  +  L A D+D+G N ++ Y I    +D+       
Sbjct: 790  NVHAPEFLDFPNEIRVNESAPIGFVLARLAARDRDLGYNGKLVYGISAGDSDS------- 842

Query: 77   XXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATI 136
                        VF ID  +G L     LDRE+   Y + +   D   P   + S++  +
Sbjct: 843  ------------VFGIDPDTGELRLIGRLDREREDEYFLNITVYDLGKP---QKSASRML 887

Query: 137  HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNT 196
             V+++D NDN P+F +   +  V E  +  +  +I +   TDAD+G N+ + Y+++   +
Sbjct: 888  AVSVLDVNDNAPKFEKALASFRVSE--AALNGTIIFRANTTDADLGENAQVAYSLVTDTS 945

Query: 197  QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD--GG---------SPSRSNTTQLLI 245
               F +D  +G +++   LD E+  SY L IRA D  GG         +P+  +   + +
Sbjct: 946  --DFRVDRTTGVLTVFGKLDRERQSSYELRIRATDKNGGNDKGEPDFDNPALYSEALVRV 1003

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
            ++ DVNDNAP+F  + +   V E+VP+   I  ++A D DEG    + Y+ +++  +   
Sbjct: 1004 SVDDVNDNAPKFALTSYTVKVREDVPVWSVIAVIEATDPDEGPGGIIEYSFSEEMESEGF 1063

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
                 ID  SG + +  +LD E +  + L + A D G+P  S+                 
Sbjct: 1064 ---FGIDKLSGTIRSLQKLDFEERQVHTLTIVAKDKGEPSLSSETILIIEVVDVNENLHA 1120

Query: 366  --FMPGQYEVELAEDEPPGTPVVTLTATDADE---DNRLHYEITGGNTRGRFSITSQNGR 420
              F        ++E++P  T V  + A DAD    D+R+ Y I GG+  G FSI  +   
Sbjct: 1121 PVFNDFVISASVSENQPLNTLVTQVKAKDADPPGGDSRIGYSIRGGDGVGLFSIDDE--- 1177

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASV 478
            G I     LD + +  Y LTV A D G    S    V + + D N+  P+ E   Y  SV
Sbjct: 1178 GNIRTKAVLDVEAKAGYWLTVYAQDHGVVPLSSKLQVYVEVLDENDNTPLTEQPVYYPSV 1237

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN-K 537
             E++P G +VL + A D DV    Q +++++S        + +  F+IN  +G ITT+ +
Sbjct: 1238 LENSPAGVSVLQIRAFDRDVS-PQQFSFAITS-------GNAEGYFLINSTSGLITTSGR 1289

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
             LDRE  + ++L VT RD G P LS TT V + V DVND+ PVF+++ Y   I     + 
Sbjct: 1290 KLDRENQAEHILEVTVRDDGRPVLSSTTRVVVQVDDVNDHSPVFEEKFYMVQIPASPSLD 1349

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
              + QV A D D+G NG+I Y +    + +G F I P +G++ + +    E+    ++  
Sbjct: 1350 KPLFQVLAHDQDIGKNGKIQYSI-KSGKGKGKFKIHPDTGMVYSQRGF--EAGQEFEMII 1406

Query: 658  VAIDGGTPPQSSTVIVHIK-IEDINDS--PPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
             A D G PP+S    + ++ +E   DS  PPVF+S   +  ++E+   G  +  ++A D 
Sbjct: 1407 RATDEGEPPRSHQARISVQVVETPKDSPNPPVFKSLNQSVEVTESDKAGFLVALMQATDK 1466

Query: 715  DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL 774
            D G +  + Y I  GD  + F +    G D   ++    LD+E+ +  Y L I       
Sbjct: 1467 D-GDS--LWYDIVEGDTRDEFVI----GRDDGNVLLAKQLDWET-QNFYNLTISVTDGV- 1517

Query: 775  WNDVRVEIL--VTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRI 831
             N+ R  +   V D+ND+ P + +        ++    G    ++ A D D   KL Y +
Sbjct: 1518 -NEARTSLFVKVIDINDHRPELSESIYHVEISENVVEKGEAILQLHAQDLDEDKKLFYSL 1576

Query: 832  LSG-NNANLIL--LNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
             +  + A+L +  ++  TG++TL+  L+    +   + V V D
Sbjct: 1577 HNAQSQASLQIFHVDSLTGTITLNEALDRETIQEHILTVMVKD 1619



 Score =  280 bits (687), Expect = 3e-73
 Identities = 254/887 (28%), Positives = 405/887 (45%), Gaps = 69/887 (7%)

Query: 21   PVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXX 80
            PVF+       V E   +G  V  ++ATD+D      + Y  ++V  DT           
Sbjct: 1437 PVFKSLNQSVEVTESDKAGFLVALMQATDKD---GDSLWY--DIVEGDT----------- 1480

Query: 81   XXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNI 140
                  +D F I    G +L    LD E    Y + +  TD  +       +  ++ V +
Sbjct: 1481 ------RDEFVIGRDDGNVLLAKQLDWETQNFYNLTISVTDGVN------EARTSLFVKV 1528

Query: 141  IDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ- 199
            ID ND+ P+ SE  Y V + E++ V     I ++ A D D   +  + Y++    +Q   
Sbjct: 1529 IDINDHRPELSESIYHVEISENV-VEKGEAILQLHAQDLD--EDKKLFYSLHNAQSQASL 1585

Query: 200  --FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF 257
              F +DSL+G ++L + LD E ++ + L +  +D G+P++ N  ++L+ + D ND+AP F
Sbjct: 1586 QIFHVDSLTGTITLNEALDRETIQEHILTVMVKDQGTPAKRNFARVLVTVHDHNDHAPTF 1645

Query: 258  YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317
             + + Q  V E  PIG ++V+V A D D G NA+L+Y+MT    +GNV    +IDP  G 
Sbjct: 1646 ISEIIQGKVFETSPIGTAVVQVIAIDRDRGENAQLSYSMT----SGNVGNVFSIDPDLGT 1701

Query: 318  VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV--EL 375
            +  + +LD  T ++Y LLV ATD G P  S +                F+    E+  E+
Sbjct: 1702 IRVARELDLATASEYILLVKATDHGSPALSNSIPVHVMVTMADNAPPRFVRSGAELAAEI 1761

Query: 376  AEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435
             E+E  G+ V  +   +A   + L +EI  GN    F I      G+I+  + LD++  +
Sbjct: 1762 YENEEIGSFVKHI---EARSTSSLQFEIVSGNIGEAFFINPST--GVISTQERLDYEDVK 1816

Query: 436  RYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495
             Y L+++AT   G S    V +++ D N+ AP F  A YT  V E A IG+ V   ++T 
Sbjct: 1817 FYNLSIAATSMSGASAQCNVIVHVLDRNDNAPQFVQAVYTGQVSEAASIGSLVFSANSTS 1876

Query: 496  SDVGINAQITYS-LSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETMSGYLLTVTA 553
            S + I A+   S L++ ++ + V    ++F  I+  TGAI T  LLD ET+  +   V  
Sbjct: 1877 SPLVIKAEDADSELNALLNYDIVEELPRKFFHIDSSTGAIRTVMLLDHETIPEFQFNVKV 1936

Query: 554  RDGGVPSLS--DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD-- 609
             D G P LS   T  V I+V DVND  P F+Q  Y A ++       +V ++ A D D  
Sbjct: 1937 SDLGKPKLSSESTAKVIITVSDVNDCPPKFQQSDYNATVLLPTWKNVAVVKLEAHDPDST 1996

Query: 610  VGLNGRIHYELDPKDREEG-SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
                 +     D  D  +G SF ID  SG +  N   + +   ++ L   A DG     S
Sbjct: 1997 SAFTNQPSLRYDIIDGNQGQSFDIDSQSGALTVNNPENMKK--SYLLHVRASDG---KYS 2051

Query: 669  STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
            S   V+IK+    +S  VF+ +     + ENS   +T+  +         N  V +SI  
Sbjct: 2052 SVAQVNIKVAKSENSGLVFQKEVYEGTVVENSTKVSTVAVLNV--LGSALNEHVVFSIL- 2108

Query: 729  GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR---VEILVT 785
             + +  F +    G   A   T +  D E+   KYEL++ A S      V    V + V 
Sbjct: 2109 -NPTEMFVIGPTSG---AISTTGIRFDRET-IDKYELIVEANSQVPTQRVAHTIVNVTVL 2163

Query: 786  DVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRI-LSGNNANLILLNE 844
            D+NDN P+  +         D        +V A D D  D  + R  L   +  L  +N 
Sbjct: 2164 DINDNCPIFVNLPYYAVVSVDAQKGDVIMKVHAIDLDSGDNGEVRYELKKGHGELFKVNR 2223

Query: 845  TTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEM 891
             TG ++L   L  +  +   M  +   G++     + ++V++I   M
Sbjct: 2224 KTGEISLKQNLEGHNREYQLMIAAYDGGISPCSVEISVNVKVIDRSM 2270



 Score =  273 bits (670), Expect = 4e-71
 Identities = 233/848 (27%), Positives = 372/848 (43%), Gaps = 59/848 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I VLD ND  P F    Y  S+ E A  GT +L L A D D G N+++ Y IE  TAD L
Sbjct: 2363 ILVLDVNDCPPEFSQDSYNISISEAALFGTELLRLVARDNDTGINSKIRYAIENRTADEL 2422

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                             D+F +D   G +  + SLD E    +   V A D+  P    L
Sbjct: 2423 GEN------------TLDLFHVDPEEGIVYLKRSLDHETADSHHFTVVAMDRGVP---SL 2467

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            SSTA + + +ID NDN P+F + +Y   + E+        +  + A+D D+  +  + Y 
Sbjct: 2468 SSTAHVWLTVIDMNDNPPKFEQSSYNCFLSEE--AERGQFVTVVSASDPDL-LDDKLVYT 2524

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I+GGN Q  +SID  +G ++L+   ++   +   L +   DG     ++  ++ I I   
Sbjct: 2525 IVGGNDQQTYSIDQSTGIITLINMQNFADDKMTLLNVSVSDG---VYTSFARIKIEILPA 2581

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            N + P+F   + + SV EN   G  +  V A D D G    + Y++ + DY         
Sbjct: 2582 NRHHPKFLNPVVEVSVLENQLPGKLVTSVLATDKDFGEYGTIEYSI-NSDYLKEF---FE 2637

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            ID  +G + T   LDRE    +++ V A+DGG   +S                  F+  +
Sbjct: 2638 IDRENGDIVTKKSLDREKHKLFEIPVMASDGGG--KSGFVIVRVKVTDENDNSPVFLLKE 2695

Query: 371  YEVELAEDEPPGTPVVTLTATDADEDN--RLHYEI---TGGNTRGRFSITSQNGRGLI-T 424
            Y+  +  +    +  + + A DADE +  ++ Y I        +  F I    G   +  
Sbjct: 2696 YKASIYGNLTLNSAFLKVKALDADEGDAAKIIYSIFEPQNSEIKNIFGINPDTGAVFLKK 2755

Query: 425  VAQPLDFKQERRYVLTVSATDSGGRSD--TAMVQINITDANNYAPVFENAPYTASVFEDA 482
             A+P    + + + L V A D G  S      V+I I    +  P+FE       V E +
Sbjct: 2756 SAKPW---ETQPFQLFVRAQDKGLASHHVDVPVEIYIMGPEDIPPLFERKEDKFFVSETS 2812

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
             IGT +  +         N+ +T  L S       A  D  F ++P+T  +T +  LDRE
Sbjct: 2813 TIGTPITRLRTV---TNTNSTVTCRLVS-------AGDDFPFAVDPKTCRVTLSGNLDRE 2862

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
                Y++ V A     P L+   ++ + V+D ND+ P F+   Y+  + E+   GTS+ +
Sbjct: 2863 VKDSYMIGVLAETDSSPPLTALAEITLQVLDENDHAPKFESNPYSIAVAENIEEGTSILK 2922

Query: 603  VGATDADVGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKALDRESVATHDLKAVAID 661
            V A D D+G NG + Y       E  + F ID  +G I +   LD+E    +  + +A D
Sbjct: 2923 VVAHDNDLGSNGEVRYSFGSDIGELANVFTIDAYTGWISSLVQLDKEQQPEYKFQVIATD 2982

Query: 662  GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY--ISENSPIGTTIGEIRAHDPDEGPN 719
             G P   S   V +K++D ND+P  F S    +   + E++  GT + E+   D D   N
Sbjct: 2983 NGNPRHFSRTSVLVKLKDYNDNPSAFSSAESGYQATVKEDALPGTVVVELTTVDKDTELN 3042

Query: 720  AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR 779
              + + I  GD  + F++ +       ++     LD E+ R +YEL++         + R
Sbjct: 3043 TALDFYIISGDPRSQFAIRS-----TGQVYVAKALDRET-RDRYELLVVGTDGKFVFETR 3096

Query: 780  VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA--YDADVTDKLQYRILSGNNA 837
            V + V DVNDN P    ++      +   P      V A  YD +   KL++ +  G N 
Sbjct: 3097 VIVQVLDVNDNPPYCLKYRYREVLSEGSHPGSYVLTVLATDYDDEPNAKLRFYLTGGKNE 3156

Query: 838  NLILLNET 845
               L  ET
Sbjct: 3157 KFSLDKET 3164



 Score =  264 bits (646), Expect = 3e-68
 Identities = 228/807 (28%), Positives = 369/807 (45%), Gaps = 78/807 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V D NDHSPVFE + Y   +    S    +  + A DQDIGKN +++Y+I+       
Sbjct: 1321 VQVDDVNDHSPVFEEKFYMVQIPASPSLDKPLFQVLAHDQDIGKNGKIQYSIK------- 1373

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                            +  F+I   +G + ++   +  +   + ++++ATD+  P     
Sbjct: 1374 ------------SGKGKGKFKIHPDTGMVYSQRGFEAGQ--EFEMIIRATDEGEPPRSHQ 1419

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +  +   V    D+ N P F     +V V E  S     ++A ++ATD D     ++ Y 
Sbjct: 1420 ARISVQVVETPKDSPNPPVFKSLNQSVEVTE--SDKAGFLVALMQATDKD---GDSLWYD 1474

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I+ G+T+ +F I    G+V L K LD+E    Y L I   DG + +R   T L + + D+
Sbjct: 1475 IVEGDTRDEFVIGRDDGNVLLAKQLDWETQNFYNLTISVTDGVNEAR---TSLFVKVIDI 1531

Query: 251  NDNAPRFYTSLFQESVSEN-VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            ND+ P    S++   +SEN V  G +I+++ A D DE  + +L Y++ +     ++ +  
Sbjct: 1532 NDHRPELSESIYHVEISENVVEKGEAILQLHAQDLDE--DKKLFYSLHNAQSQASLQI-F 1588

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             +D  +G +  +  LDRET  ++ L V   D G P +   A               F+  
Sbjct: 1589 HVDSLTGTITLNEALDRETIQEHILTVMVKDQGTPAKRNFARVLVTVHDHNDHAPTFISE 1648

Query: 370  QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
              + ++ E  P GT VV + A D D  E+ +L Y +T GN    FSI      G I VA+
Sbjct: 1649 IIQGKVFETSPIGTAVVQVIAIDRDRGENAQLSYSMTSGNVGNVFSIDPD--LGTIRVAR 1706

Query: 428  PLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVF--ENAPYTASVFEDAP 483
             LD      Y+L V ATD G    S++  V + +T A+N  P F    A   A ++E+  
Sbjct: 1707 ELDLATASEYILLVKATDHGSPALSNSIPVHVMVTMADNAPPRFVRSGAELAAEIYENEE 1766

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
            IG+ V           I A+ T SL  EI +  +    + F INP TG I+T + LD E 
Sbjct: 1767 IGSFV---------KHIEARSTSSLQFEIVSGNIG---EAFFINPSTGVISTQERLDYED 1814

Query: 544  MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
            +  Y L++ A    +   S   +V + V+D NDN P F Q +YT  + E A +G+ V   
Sbjct: 1815 VKFYNLSIAAT--SMSGASAQCNVIVHVLDRNDNAPQFVQAVYTGQVSEAASIGSLVFSA 1872

Query: 604  GAT---------DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654
             +T         DAD  LN  ++Y++  ++     F ID ++G IRT   LD E++    
Sbjct: 1873 NSTSSPLVIKAEDADSELNALLNYDI-VEELPRKFFHIDSSTGAIRTVMLLDHETIPEFQ 1931

Query: 655  LKAVAIDGGTPPQS--STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
                  D G P  S  ST  V I + D+ND PP F+       +   +     + ++ AH
Sbjct: 1932 FNVKVSDLGKPKLSSESTAKVIITVSDVNDCPPKFQQSDYNATVLLPTWKNVAVVKLEAH 1991

Query: 713  DPDEGP----NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768
            DPD          + Y I  G+   SF ++++ G+       +   + E+ +K Y L +R
Sbjct: 1992 DPDSTSAFTNQPSLRYDIIDGNQGQSFDIDSQSGA-------LTVNNPENMKKSYLLHVR 2044

Query: 769  AASPPLWNDVRVEILVTDVNDNAPVMK 795
            A+     +  +V I V    ++  V +
Sbjct: 2045 ASDGKYSSVAQVNIKVAKSENSGLVFQ 2071



 Score =  263 bits (645), Expect = 4e-68
 Identities = 239/891 (26%), Positives = 407/891 (45%), Gaps = 65/891 (7%)

Query: 8    HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
            H  + V+D ND+ P FE   Y   + E A  G  V  + A+D D+  + ++ YTI     
Sbjct: 2472 HVWLTVIDMNDNPPKFEQSSYNCFLSEEAERGQFVTVVSASDPDL-LDDKLVYTI----- 2525

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
              +   D            Q  + ID  +G ++T  ++      + T+L  +      VS
Sbjct: 2526 --VGGND------------QQTYSIDQSTG-IITLINMQNFADDKMTLLNVS------VS 2564

Query: 128  DRL-SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
            D + +S A I + I+  N ++P+F      VSV E  +     ++  + ATD D G    
Sbjct: 2565 DGVYTSFARIKIEILPANRHHPKFLNPVVEVSVLE--NQLPGKLVTSVLATDKDFGEYGT 2622

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            I Y+I     +  F ID  +GD+   K+LD E+ + + + + A DGG   +S    + + 
Sbjct: 2623 IEYSINSDYLKEFFEIDRENGDIVTKKSLDREKHKLFEIPVMASDGG--GKSGFVIVRVK 2680

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            + D NDN+P F    ++ S+  N+ +  + ++V+A DADEG  A++ Y++ +      + 
Sbjct: 2681 VTDENDNSPVFLLKEYKASIYGNLTLNSAFLKVKALDADEGDAAKIIYSIFEPQ-NSEIK 2739

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
                I+P +G V+            +QL V A D G                       F
Sbjct: 2740 NIFGINPDTGAVFLKKSAKPWETQPFQLFVRAQDKGLASHHVDVPVEIYIMGPEDIPPLF 2799

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
               + +  ++E    GTP+  L  T  + ++ +   +        F++  +  R  +T++
Sbjct: 2800 ERKEDKFFVSETSTIGTPITRL-RTVTNTNSTVTCRLVSAGDDFPFAVDPKTCR--VTLS 2856

Query: 427  QPLDFKQERRYVLTVSATDSGGRSDTAMVQI--NITDANNYAPVFENAPYTASVFEDAPI 484
              LD + +  Y++ V A        TA+ +I   + D N++AP FE+ PY+ +V E+   
Sbjct: 2857 GNLDREVKDSYMIGVLAETDSSPPLTALAEITLQVLDENDHAPKFESNPYSIAVAENIEE 2916

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            GT++L V A D+D+G N ++ YS  S+I   A       F I+  TG I++   LD+E  
Sbjct: 2917 GTSILKVVAHDNDLGSNGEVRYSFGSDIGELA-----NVFTIDAYTGWISSLVQLDKEQQ 2971

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK--QQLYTANIMEDALVGTSVSQ 602
              Y   V A D G P     T V + + D NDN   F   +  Y A + EDAL GT V +
Sbjct: 2972 PEYKFQVIATDNGNPRHFSRTSVLVKLKDYNDNPSAFSSAESGYQATVKEDALPGTVVVE 3031

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
            +   D D  LN  + + +   D     F I  ++G +   KALDRE+   ++L  V  DG
Sbjct: 3032 LTTVDKDTELNTALDFYIISGD-PRSQFAI-RSTGQVYVAKALDRETRDRYELLVVGTDG 3089

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
                ++  +   +++ D+ND+PP          +SE S  G+ +  + A D D+ PNA +
Sbjct: 3090 KFVFETRVI---VQVLDVNDNPPYCLKYRYREVLSEGSHPGSYVLTVLATDYDDEPNAKL 3146

Query: 723  HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV--IRAASPPLWN-DVR 779
             + + GG  +  FSL+   G     L T+  LD ES + KY L   ++      W    +
Sbjct: 3147 RFYLTGG-KNEKFSLDKETG----VLKTVGQLDRES-QAKYILTAHVQDRDKTSWECSSQ 3200

Query: 780  VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDAD--VTDKLQYRILSGNN 836
            +EIL++D+NDNAP     Q       +   VG    +V A D D  +  K++Y  L   N
Sbjct: 3201 LEILISDLNDNAPRF-SMQSYSATLPEDVEVGTLVTKVHATDDDIGINRKIRYEFLDSAN 3259

Query: 837  ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRL 886
             + + ++  +G +TL+  L+     +  + +   D G  ++ ++  L V +
Sbjct: 3260 DHFV-ISPDSGIVTLAKPLDRETKAMYNVSIQAMDQGTPQLSSVTFLIVNV 3309



 Score =  263 bits (644), Expect = 6e-68
 Identities = 250/879 (28%), Positives = 387/879 (44%), Gaps = 70/879 (7%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I +L  N H P F     E SV E    G  V ++ ATD+D G+   +EY+I    +D 
Sbjct: 2575 KIEILPANRHHPKFLNPVVEVSVLENQLPGKLVTSVLATDKDFGEYGTIEYSI---NSDY 2631

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            L                ++ F ID  +G ++T+ SLDREK   + + V A+D        
Sbjct: 2632 L----------------KEFFEIDRENGDIVTKKSLDREKHKLFEIPVMASDGGGK---- 2671

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             S    + V + D+NDN P F  K Y  S+  ++++  N    K+KA DAD G  + I Y
Sbjct: 2672 -SGFVIVRVKVTDENDNSPVFLLKEYKASIYGNLTL--NSAFLKVKALDADEGDAAKIIY 2728

Query: 190  AII-GGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            +I    N++++  F I+  +G V L K+    + + ++L +RAQD G  S      + I 
Sbjct: 2729 SIFEPQNSEIKNIFGINPDTGAVFLKKSAKPWETQPFQLFVRAQDKGLASHHVDVPVEIY 2788

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            I    D  P F     +  VSE   IG  I R++              T+T +  +   D
Sbjct: 2789 IMGPEDIPPLFERKEDKFFVSETSTIGTPITRLRTV-------TNTNSTVTCRLVSAGDD 2841

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
             P  +DP++  V  SG LDRE +  Y + V A     PP +A A               F
Sbjct: 2842 FPFAVDPKTCRVTLSGNLDREVKDSYMIGVLAETDSSPPLTALAEITLQVLDENDHAPKF 2901

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS--ITSQNGRGLIT 424
                Y + +AE+   GT ++ + A D D  +      + G+  G  +   T     G I+
Sbjct: 2902 ESNPYSIAVAENIEEGTSILKVVAHDNDLGSNGEVRYSFGSDIGELANVFTIDAYTGWIS 2961

Query: 425  VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAP--YTASVFE 480
                LD +Q+  Y   V ATD+G         V + + D N+    F +A   Y A+V E
Sbjct: 2962 SLVQLDKEQQPEYKFQVIATDNGNPRHFSRTSVLVKLKDYNDNPSAFSSAESGYQATVKE 3021

Query: 481  DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
            DA  GT V+ ++  D D  +N  + + +   IS +       QF I   TG +   K LD
Sbjct: 3022 DALPGTVVVELTTVDKDTELNTALDFYI---ISGDP----RSQFAIR-STGQVYVAKALD 3073

Query: 541  RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
            RET   Y L V   DG        T V + V+DVNDN P   +  Y   + E +  G+ V
Sbjct: 3074 RETRDRYELLVVGTDG---KFVFETRVIVQVLDVNDNPPYCLKYRYREVLSEGSHPGSYV 3130

Query: 601  SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
              V ATD D   N ++ + L     E+  F +D  +GV++T   LDRES A + L A   
Sbjct: 3131 LTVLATDYDDEPNAKLRFYLTGGKNEK--FSLDKETGVLKTVGQLDRESQAKYILTAHVQ 3188

Query: 661  DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
            D        +  + I I D+ND+ P F     +  + E+  +GT + ++ A D D G N 
Sbjct: 3189 DRDKTSWECSSQLEILISDLNDNAPRFSMQSYSATLPEDVEVGTLVTKVHATDDDIGINR 3248

Query: 721  VVHYSIKGGDDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRA---ASPPLWN 776
             + Y     D +N   +     S  + +VT+   LD E+ +  Y + I+A    +P L +
Sbjct: 3249 KIRYEFL--DSANDHFVI----SPDSGIVTLAKPLDRET-KAMYNVSIQAMDQGTPQLSS 3301

Query: 777  DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPA--YDADVTDKLQYRILS 833
               + + V D+NDN P     +  F    +   VG    RV A   D  V   + Y I+ 
Sbjct: 3302 VTFLIVNVQDINDNPPEFTS-KYYFARVPEIDAVGTEVARVLATSKDTGVNADVYYTIVG 3360

Query: 834  GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            GN      ++  +G ++++ QL+    K   + +   DG
Sbjct: 3361 GNEHKKFEIDTKSGVVSIAEQLDYERAKDYFLTIQAIDG 3399



 Score =  261 bits (640), Expect = 2e-67
 Identities = 241/808 (29%), Positives = 376/808 (46%), Gaps = 93/808 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V D NDH+P F  +  +  V E +  GT V+ + A D+D G+NA++ Y++        
Sbjct: 1633 VTVHDHNDHAPTFISEIIQGKVFETSPIGTAVVQVIAIDRDRGENAQLSYSM-------- 1684

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           V +VF ID   G +     LD    + Y +LVKATD  SP    L
Sbjct: 1685 -----------TSGNVGNVFSIDPDLGTIRVARELDLATASEYILLVKATDHGSPA---L 1730

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S++  +HV +   ++  P+F      ++ +    + +N  I        +  + S++++ 
Sbjct: 1731 SNSIPVHVMVTMADNAPPRFVRSGAELAAE----IYENEEIGSF-VKHIEARSTSSLQFE 1785

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD-GGSPSRSNTTQLLINIRD 249
            I+ GN    F I+  +G +S  + LDYE V+ Y L I A    G+ ++ N   +++++ D
Sbjct: 1786 IVSGNIGEAFFINPSTGVISTQERLDYEDVKFYNLSIAATSMSGASAQCN---VIVHVLD 1842

Query: 250  VNDNAPRFYTSLFQESVSENVPIG---------YSIVRVQAYDADEGVNAELTYTMTDKD 300
             NDNAP+F  +++   VSE   IG          S + ++A DAD  +NA L Y + +  
Sbjct: 1843 RNDNAPQFVQAVYTGQVSEAASIGSLVFSANSTSSPLVIKAEDADSELNALLNYDIVE-- 1900

Query: 301  YTGNVDLP---ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRS--ATATXXXX 355
                 +LP     ID  +G + T   LD ET  ++Q  V  +D G P  S  +TA     
Sbjct: 1901 -----ELPRKFFHIDSSTGAIRTVMLLDHETIPEFQFNVKVSDLGKPKLSSESTAKVIIT 1955

Query: 356  XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN------RLHYEITGGNTR 409
                      F    Y   +         VV L A D D  +       L Y+I  GN  
Sbjct: 1956 VSDVNDCPPKFQQSDYNATVLLPTWKNVAVVKLEAHDPDSTSAFTNQPSLRYDIIDGNQG 2015

Query: 410  GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVF 469
              F I SQ+  G +TV  P + K  + Y+L V A+D G  S  A V I +  + N   VF
Sbjct: 2016 QSFDIDSQS--GALTVNNPENMK--KSYLLHVRASD-GKYSSVAQVNIKVAKSENSGLVF 2070

Query: 470  ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
            +   Y  +V E++   +TV V++   S   +N  + +S         + +  + FVI P 
Sbjct: 2071 QKEVYEGTVVENSTKVSTVAVLNVLGS--ALNEHVVFS---------ILNPTEMFVIGPT 2119

Query: 530  TGAITTNKL-LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588
            +GAI+T  +  DRET+  Y L V A           T V ++V+D+NDN P+F    Y A
Sbjct: 2120 SGAISTTGIRFDRETIDKYELIVEANSQVPTQRVAHTIVNVTVLDINDNCPIFVNLPYYA 2179

Query: 589  NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648
             +  DA  G  + +V A D D G NG + YEL  K      F ++  +G I   + L+  
Sbjct: 2180 VVSVDAQKGDVIMKVHAIDLDSGDNGEVRYEL--KKGHGELFKVNRKTGEISLKQNLEGH 2237

Query: 649  SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG- 707
            +   + L   A DGG  P S  + V++K+  I+ S PVF+    T  + E+  + + +  
Sbjct: 2238 N-REYQLMIAAYDGGISPCSVEISVNVKV--IDRSMPVFDKQFYTDSVLESIEVHSPLAL 2294

Query: 708  EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELV 766
             I+A  P    N  + YSI  G+D   F+L+   G     ++ +VD LDYE  +K+YEL 
Sbjct: 2295 SIQAESP---LNRKLIYSITKGNDFEEFALDFNTG-----VIYVVDELDYEQ-KKQYELT 2345

Query: 767  IRAAS--PPLWNDVRVEILVTDVNDNAP 792
            +RA      ++ +V V ILV DVND  P
Sbjct: 2346 VRATDSVSGVYAEVLVSILVLDVNDCPP 2373



 Score =  252 bits (617), Expect = 1e-64
 Identities = 224/820 (27%), Positives = 368/820 (44%), Gaps = 53/820 (6%)

Query: 86   VQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145
            + + F I+  +G + T+  LD E V  Y + + AT  +       S+   + V+++D ND
Sbjct: 1791 IGEAFFINPSTGVISTQERLDYEDVKFYNLSIAATSMSGA-----SAQCNVIVHVLDRND 1845

Query: 146  NYPQFSEKTYTVSVDEDISV---------TDNPVIAKIKATDADVGANSAIRYAIIGGNT 196
            N PQF +  YT  V E  S+         T +P++  IKA DAD   N+ + Y I+    
Sbjct: 1846 NAPQFVQAVYTGQVSEAASIGSLVFSANSTSSPLV--IKAEDADSELNALLNYDIVEELP 1903

Query: 197  QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQLLINIRDVNDNA 254
            +  F IDS +G +  V  LD+E +  ++  ++  D G P  S  +T +++I + DVND  
Sbjct: 1904 RKFFHIDSSTGAIRTVMLLDHETIPEFQFNVKVSDLGKPKLSSESTAKVIITVSDVNDCP 1963

Query: 255  PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR 314
            P+F  S +  +V        ++V+++A+D D         ++      GN      ID +
Sbjct: 1964 PKFQQSDYNATVLLPTWKNVAVVKLEAHDPDSTSAFTNQPSLRYDIIDGNQGQSFDIDSQ 2023

Query: 315  SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374
            SG +  +       +  Y L V A+DG     S+ A               F    YE  
Sbjct: 2024 SGALTVNNP--ENMKKSYLLHVRASDG---KYSSVAQVNIKVAKSENSGLVFQKEVYEGT 2078

Query: 375  LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434
            + E+    + V  L    +  +  + + I   N    F I   +G  + T     D +  
Sbjct: 2079 VVENSTKVSTVAVLNVLGSALNEHVVFSIL--NPTEMFVIGPTSG-AISTTGIRFDRETI 2135

Query: 435  RRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492
             +Y L V A         A   +N+T  D N+  P+F N PY A V  DA  G  ++ V 
Sbjct: 2136 DKYELIVEANSQVPTQRVAHTIVNVTVLDINDNCPIFVNLPYYAVVSVDAQKGDVIMKVH 2195

Query: 493  ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552
            A D D G N ++ Y L           H + F +N +TG I+  + L+      Y L + 
Sbjct: 2196 AIDLDSGDNGEVRYELKKG--------HGELFKVNRKTGEISLKQNLEGHNRE-YQLMIA 2246

Query: 553  ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612
            A DGG+   S    V + V+D   + PVF +Q YT +++E   V + ++   +  A+  L
Sbjct: 2247 AYDGGISPCSVEISVNVKVID--RSMPVFDKQFYTDSVLESIEVHSPLAL--SIQAESPL 2302

Query: 613  NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672
            N ++ Y +  K  +   F +D  +GVI     LD E    ++L   A D  +   +  V+
Sbjct: 2303 NRKLIYSIT-KGNDFEEFALDFNTGVIYVVDELDYEQKKQYELTVRATDSVSGVYAE-VL 2360

Query: 673  VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG--GD 730
            V I + D+ND PP F  D     ISE +  GT +  + A D D G N+ + Y+I+    D
Sbjct: 2361 VSILVLDVNDCPPEFSQDSYNISISEAALFGTELLRLVARDNDTGINSKIRYAIENRTAD 2420

Query: 731  DSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRA--ASPPLWNDVRVEILVTDV 787
            +    +L+      +  +V +   LD+E+    +  V+      P L +   V + V D+
Sbjct: 2421 ELGENTLDLFHVDPEEGIVYLKRSLDHETADSHHFTVVAMDRGVPSLSSTAHVWLTVIDM 2480

Query: 788  NDNAPVMKDFQIIFNNY-KDCFPVGPFGRV-PAYDADVTD-KLQYRILSGNNANLILLNE 844
            NDN P  +  Q  +N +  +    G F  V  A D D+ D KL Y I+ GN+     +++
Sbjct: 2481 NDNPPKFE--QSSYNCFLSEEAERGQFVTVVSASDPDLLDDKLVYTIVGGNDQQTYSIDQ 2538

Query: 845  TTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884
            +TG +TL    N    K+  + VSV+DGV    A +++ +
Sbjct: 2539 STGIITLINMQNFADDKMTLLNVSVSDGVYTSFARIKIEI 2578



 Score =  251 bits (614), Expect = 2e-64
 Identities = 225/849 (26%), Positives = 379/849 (44%), Gaps = 57/849 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND  P F+   Y A+V         V+ L+A D D       + ++     D  
Sbjct: 1954 ITVSDVNDCPPKFQQSDYNATVLLPTWKNVAVVKLEAHDPDSTSAFTNQPSLRYDIIDGN 2013

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
              +                F ID +SGAL      + +K   Y + V+A+D       + 
Sbjct: 2014 QGQS---------------FDIDSQSGALTVNNPENMKK--SYLLHVRASD------GKY 2050

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            SS A +++ +    ++   F ++ Y  +V E+ +      +  +  +      N  + ++
Sbjct: 2051 SSVAQVNIKVAKSENSGLVFQKEVYEGTVVENSTKVSTVAVLNVLGS----ALNEHVVFS 2106

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            I+  N    F I   SG +S      D E +  Y L++ A       R   T + + + D
Sbjct: 2107 IL--NPTEMFVIGPTSGAISTTGIRFDRETIDKYELIVEANSQVPTQRVAHTIVNVTVLD 2164

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            +NDN P F    +   VS +   G  I++V A D D G N E+ Y +      G+ +L  
Sbjct: 2165 INDNCPIFVNLPYYAVVSVDAQKGDVIMKVHAIDLDSGDNGEVRYELKK----GHGEL-F 2219

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             ++ ++G +     L+   + +YQL++ A DGG  P S   +              F   
Sbjct: 2220 KVNRKTGEISLKQNLEGHNR-EYQLMIAAYDGGISPCSVEISVNVKVIDRSMPV--FDKQ 2276

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
             Y   + E     +P+      ++  + +L Y IT GN    F++    G  +I V   L
Sbjct: 2277 FYTDSVLESIEVHSPLALSIQAESPLNRKLIYSITKGNDFEEFALDFNTG--VIYVVDEL 2334

Query: 430  DFKQERRYVLTVSATDS-GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
            D++Q+++Y LTV ATDS  G     +V I + D N+  P F    Y  S+ E A  GT +
Sbjct: 2335 DYEQKKQYELTVRATDSVSGVYAEVLVSILVLDVNDCPPEFSQDSYNISISEAALFGTEL 2394

Query: 489  LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
            L + A D+D GIN++I Y++ +  ++E   +    F ++P+ G +   + LD ET   + 
Sbjct: 2395 LRLVARDNDTGINSKIRYAIENRTADELGENTLDLFHVDPEEGIVYLKRSLDHETADSHH 2454

Query: 549  LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
             TV A D GVPSLS T  V ++V+D+NDN P F+Q  Y   + E+A  G  V+ V A+D 
Sbjct: 2455 FTVVAMDRGVPSLSSTAHVWLTVIDMNDNPPKFEQSSYNCFLSEEAERGQFVTVVSASDP 2514

Query: 609  DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
            D+ L+ ++ Y +     ++ ++ ID ++G+I     ++ ++ A   +  + +       +
Sbjct: 2515 DL-LDDKLVYTI-VGGNDQQTYSIDQSTGII---TLINMQNFADDKMTLLNVSVSDGVYT 2569

Query: 669  STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
            S   + I+I   N   P F +  +   + EN   G  +  + A D D G    + YSI  
Sbjct: 2570 SFARIKIEILPANRHHPKFLNPVVEVSVLENQLPGKLVTSVLATDKDFGEYGTIEYSINS 2629

Query: 729  GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND-VRVEILVTDV 787
                  F ++   G    ++VT   LD E   K +E+ + A+     +  V V + VTD 
Sbjct: 2630 DYLKEFFEIDRENG----DIVTKKSLDREK-HKLFEIPVMASDGGGKSGFVIVRVKVTDE 2684

Query: 788  NDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGNNA---NLILL 842
            NDN+PV    +   + Y +      F +V A DAD  D  K+ Y I    N+   N+  +
Sbjct: 2685 NDNSPVFLLKEYKASIYGNLTLNSAFLKVKALDADEGDAAKIIYSIFEPQNSEIKNIFGI 2744

Query: 843  NETTGSMTL 851
            N  TG++ L
Sbjct: 2745 NPDTGAVFL 2753



 Score =  232 bits (568), Expect = 9e-59
 Identities = 186/590 (31%), Positives = 281/590 (47%), Gaps = 39/590 (6%)

Query: 105 LDREKVARYTVLVKATDQASPVSDR---LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE 161
           L+RE+  +Y + +KAT +     +R   L +  T+ V I+D ND  P F    Y  +V E
Sbjct: 160 LNRERKDKYVLEIKATARRHDGKNRVTLLEAQTTVAVTILDTNDLNPLFYPTEYEATVTE 219

Query: 162 DISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVR 221
           D  V  +  I K+ A DAD+G N  I Y+        QF++  +SG V+L + L Y +  
Sbjct: 220 DTPVHKS--ILKVSAEDADLGTNGEIYYSF--AEKTEQFAVHPVSGVVTLTRPLRYVERP 275

Query: 222 SYRLVIRAQDGGS----PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277
            Y L ++A+D G+      R++  +L I++R VN +AP        E +  +    Y+IV
Sbjct: 276 LYELTVQARDRGALYRMTPRASNARLTIHVRQVNLHAPEISVRHLPEILEHSNADTYAIV 335

Query: 278 RVQAYDADEGVNAEL-TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK-YQLL 335
           RV   D D G + E+ +  +   D  G+  +     P    +     LDRE   + Y L 
Sbjct: 336 RV--LDRDTGPHGEIASLEIVAGDPDGHFRVRPLPTPGEYSIQVLKLLDREAAPQGYNLT 393

Query: 336 VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395
           + A D G PPR +  +              F    Y+V++ E  P  +PV+ L  +DAD+
Sbjct: 394 LRAVDRGTPPRFSYKSVPVHLADLNDNAPIFSTEIYDVKVPETAPVNSPVIRLKVSDADQ 453

Query: 396 -DNRLHY-EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG----R 449
             N L + EI GGN  G F I +    G++  A PLD + +  Y LTVSA D G     +
Sbjct: 454 GKNALVFLEIVGGNEGGEFYINADT--GMLYTAVPLDAETKAFYTLTVSAVDQGNAGTRK 511

Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509
             +A V+I + D N+  P FE +     + E+ P GT+V  V A D D G NA I+YS+ 
Sbjct: 512 QSSAKVKIYVIDTNDNDPEFEKSEMLVYLDENEPAGTSVCKVVARDKDSGENAYISYSID 571

Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS-GYLLTVTARDGGVP-SLSDTTDV 567
           + I           F I+  +G + T +LLD ETM   YLL V A D G+P        +
Sbjct: 572 N-IKR-------VPFEIDHFSGVVKTKQLLDYETMKREYLLHVRANDWGLPYRRQSEIQL 623

Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627
            I + +VNDN P F++     ++     VGT +  V A D D G    I Y +      +
Sbjct: 624 RIKLRNVNDNRPQFEKIDCVGHVSRYVQVGTEIITVSAIDFDAG--NIITYRIVSGGNAD 681

Query: 628 GSFVIDPASGVIRTNKALDRESVATHDL--KAVAIDGGTPPQSSTVIVHI 675
           G F +DP SGV+  + A D   + T ++     A DG      +T+ +H+
Sbjct: 682 GCFALDPTSGVL--SVACDLSDLKTQEMIVNVTATDGTHFADVNTLRIHL 729



 Score =  210 bits (512), Expect = 6e-52
 Identities = 226/901 (25%), Positives = 381/901 (42%), Gaps = 84/901 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGA-SSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            + V+D NDH P      Y   + E     G  +L L A  QD+ ++ ++ Y++       
Sbjct: 1526 VKVIDINDHRPELSESIYHVEISENVVEKGEAILQLHA--QDLDEDKKLFYSLH------ 1577

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             N +               +F +D  +G +    +LDRE +  + + V   DQ +P    
Sbjct: 1578 -NAQSQASL---------QIFHVDSLTGTITLNEALDRETIQEHILTVMVKDQGTPAKRN 1627

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
                A + V + D ND+ P F  +     V E   +     + ++ A D D G N+ + Y
Sbjct: 1628 F---ARVLVTVHDHNDHAPTFISEIIQGKVFETSPI--GTAVVQVIAIDRDRGENAQLSY 1682

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            ++  GN    FSID   G + + + LD      Y L+++A D GSP+ SN+  + + +  
Sbjct: 1683 SMTSGNVGNVFSIDPDLGTIRVARELDLATASEYILLVKATDHGSPALSNSIPVHVMVTM 1742

Query: 250  VNDNAPRFYTSLFQ--ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
             ++  PRF  S  +    + EN  IG  +  ++A           T ++  +  +GN+  
Sbjct: 1743 ADNAPPRFVRSGAELAAEIYENEEIGSFVKHIEARS---------TSSLQFEIVSGNIGE 1793

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
               I+P +G + T  +LD E    Y L + AT       SA                 F+
Sbjct: 1794 AFFINPSTGVISTQERLDYEDVKFYNLSIAATSMSGA--SAQCNVIVHVLDRNDNAPQFV 1851

Query: 368  PGQYEVELAEDEPPGTPVVTLTAT---------DADEDNR--LHYEITGGNTRGRFSITS 416
               Y  +++E    G+ V +  +T         DAD +    L+Y+I     R  F I S
Sbjct: 1852 QAVYTGQVSEAASIGSLVFSANSTSSPLVIKAEDADSELNALLNYDIVEELPRKFFHIDS 1911

Query: 417  QNGRGLITVAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNYAPVFENA 472
              G   I     LD +    +   V  +D G        TA V I ++D N+  P F+ +
Sbjct: 1912 STGA--IRTVMLLDHETIPEFQFNVKVSDLGKPKLSSESTAKVIITVSDVNDCPPKFQQS 1969

Query: 473  PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
             Y A+V         V+ + A D D         SL  +I +    +  Q F I+ Q+GA
Sbjct: 1970 DYNATVLLPTWKNVAVVKLEAHDPDSTSAFTNQPSLRYDIID---GNQGQSFDIDSQSGA 2026

Query: 533  ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592
            +T N          YLL V A DG     S    V I V    ++  VF++++Y   ++E
Sbjct: 2027 LTVNN--PENMKKSYLLHVRASDG---KYSSVAQVNIKVAKSENSGLVFQKEVYEGTVVE 2081

Query: 593  DALVGTSVSQVGATDA-DVGLNGRIHYE-LDPKDREEGSFVIDPASGVIRTNKA-LDRES 649
            ++   T VS V   +     LN  + +  L+P +     FVI P SG I T     DRE+
Sbjct: 2082 NS---TKVSTVAVLNVLGSALNEHVVFSILNPTEM----FVIGPTSGAISTTGIRFDRET 2134

Query: 650  VATHDLKAVAIDGGTPPQS-STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
            +  ++L  V  +   P Q  +  IV++ + DIND+ P+F +      +S ++  G  I +
Sbjct: 2135 IDKYEL-IVEANSQVPTQRVAHTIVNVTVLDINDNCPIFVNLPYYAVVSVDAQKGDVIMK 2193

Query: 709  IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768
            + A D D G N  V Y +K G     F +  + G    E+    +L  E   ++Y+L+I 
Sbjct: 2194 VHAIDLDSGDNGEVRYELKKGH-GELFKVNRKTG----EISLKQNL--EGHNREYQLMIA 2246

Query: 769  AASPPLWN-DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPAYDADVTDK 826
            A    +    V + + V  ++ + PV  D Q   ++  +   V  P       ++ +  K
Sbjct: 2247 AYDGGISPCSVEISVNVKVIDRSMPVF-DKQFYTDSVLESIEVHSPLALSIQAESPLNRK 2305

Query: 827  LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886
            L Y I  GN+     L+  TG + +  +L+    K   + V  TD V+ + A + +S+ +
Sbjct: 2306 LIYSITKGNDFEEFALDFNTGVIYVVDELDYEQKKQYELTVRATDSVSGVYAEVLVSILV 2365

Query: 887  I 887
            +
Sbjct: 2366 L 2366



 Score =  196 bits (479), Expect = 5e-48
 Identities = 166/573 (28%), Positives = 267/573 (46%), Gaps = 36/573 (6%)

Query: 324 LDRETQAKYQLLVTAT----DGGDPPR--SATATXXXXXXXXXXXXXXFMPGQYEVELAE 377
           L+RE + KY L + AT    DG +      A  T              F P +YE  + E
Sbjct: 160 LNRERKDKYVLEIKATARRHDGKNRVTLLEAQTTVAVTILDTNDLNPLFYPTEYEATVTE 219

Query: 378 DEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437
           D P    ++ ++A DAD         +      +F++   +G  ++T+ +PL + +   Y
Sbjct: 220 DTPVHKSILKVSAEDADLGTNGEIYYSFAEKTEQFAVHPVSG--VVTLTRPLRYVERPLY 277

Query: 438 VLTVSATDSGG------RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491
            LTV A D G       R+  A + I++   N +AP   +  +   + E +    T  +V
Sbjct: 278 ELTVQARDRGALYRMTPRASNARLTIHVRQVNLHAPEI-SVRHLPEILEHSN-ADTYAIV 335

Query: 492 SATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM-SGYLLT 550
              D D G + +I  SL   ++ +   H   + +  P   +I   KLLDRE    GY LT
Sbjct: 336 RVLDRDTGPHGEIA-SLEI-VAGDPDGHFRVRPLPTPGEYSIQVLKLLDREAAPQGYNLT 393

Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610
           + A D G P       V + + D+NDN P+F  ++Y   + E A V + V ++  +DAD 
Sbjct: 394 LRAVDRGTPPRFSYKSVPVHLADLNDNAPIFSTEIYDVKVPETAPVNSPVIRLKVSDADQ 453

Query: 611 GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID---GGTPPQ 667
           G N  +  E+     E G F I+  +G++ T   LD E+ A + L   A+D    GT  Q
Sbjct: 454 GKNALVFLEI-VGGNEGGEFYINADTGMLYTAVPLDAETKAFYTLTVSAVDQGNAGTRKQ 512

Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
           SS   V I + D ND+ P FE   +  Y+ EN P GT++ ++ A D D G NA + YSI 
Sbjct: 513 SSAK-VKIYVIDTNDNDPEFEKSEMLVYLDENEPAGTSVCKVVARDKDSGENAYISYSI- 570

Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL----WNDVRVEIL 783
             D+      E    S   +  T   LDYE+ +++Y L +RA    L     +++++ I 
Sbjct: 571 --DNIKRVPFEIDHFSGVVK--TKQLLDYETMKREYLLHVRANDWGLPYRRQSEIQLRIK 626

Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNAN-LIL 841
           + +VNDN P  +    +  +      VG     V A D D  + + YRI+SG NA+    
Sbjct: 627 LRNVNDNRPQFEKIDCV-GHVSRYVQVGTEIITVSAIDFDAGNIITYRIVSGGNADGCFA 685

Query: 842 LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN 874
           L+ T+G ++++  L+    +   + V+ TDG +
Sbjct: 686 LDPTSGVLSVACDLSDLKTQEMIVNVTATDGTH 718



 Score =  186 bits (454), Expect = 6e-45
 Identities = 157/517 (30%), Positives = 236/517 (45%), Gaps = 32/517 (6%)

Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
           T + + I D ND  P FY + ++ +V+E+ P+  SI++V A DAD G N E+ Y+  +K 
Sbjct: 192 TTVAVTILDTNDLNPLFYPTEYEATVTEDTPVHKSILKVSAEDADLGTNGEIYYSFAEKT 251

Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD----PPRSATATXXXXX 356
                     + P SG V  +  L    +  Y+L V A D G      PR++ A      
Sbjct: 252 E------QFAVHPVSGVVTLTRPLRYVERPLYELTVQARDRGALYRMTPRASNARLTIHV 305

Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRL-HYEITGGNTRGRFSI- 414
                             L         +V +   D      +   EI  G+  G F + 
Sbjct: 306 RQVNLHAPEISVRHLPEILEHSNADTYAIVRVLDRDTGPHGEIASLEIVAGDPDGHFRVR 365

Query: 415 -TSQNGRGLITVAQPLDFK-QERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFE 470
                G   I V + LD +   + Y LT+ A D G   R     V +++ D N+ AP+F 
Sbjct: 366 PLPTPGEYSIQVLKLLDREAAPQGYNLTLRAVDRGTPPRFSYKSVPVHLADLNDNAPIFS 425

Query: 471 NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
              Y   V E AP+ + V+ +  +D+D G NA +   +     NE       +F IN  T
Sbjct: 426 TEIYDVKVPETAPVNSPVIRLKVSDADQGKNALVFLEIVG--GNEG-----GEFYINADT 478

Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFKQQLYTA 588
           G + T   LD ET + Y LTV+A D G        +  V+I V+D NDN+P F++     
Sbjct: 479 GMLYTAVPLDAETKAFYTLTVSAVDQGNAGTRKQSSAKVKIYVIDTNDNDPEFEKSEMLV 538

Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648
            + E+   GTSV +V A D D G N  I Y +D   R    F ID  SGV++T + LD E
Sbjct: 539 YLDENEPAGTSVCKVVARDKDSGENAYISYSIDNIKRV--PFEIDHFSGVVKTKQLLDYE 596

Query: 649 SVATHDLKAV-AIDGGTP-PQSSTVIVHIKIEDINDSPPVFES-DCLTFYISENSPIGTT 705
           ++    L  V A D G P  + S + + IK+ ++ND+ P FE  DC+  ++S    +GT 
Sbjct: 597 TMKREYLLHVRANDWGLPYRRQSEIQLRIKLRNVNDNRPQFEKIDCVG-HVSRYVQVGTE 655

Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
           I  + A D D G N + +  + GG+    F+L+   G
Sbjct: 656 IITVSAIDFDAG-NIITYRIVSGGNADGCFALDPTSG 691



 Score =  174 bits (424), Expect = 3e-41
 Identities = 122/402 (30%), Positives = 190/402 (47%), Gaps = 31/402 (7%)

Query: 2    SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
            SV F I   +NV D ND+ P F  + Y A V E  + GT V  + AT +D G NA+V YT
Sbjct: 3301 SVTFLI---VNVQDINDNPPEFTSKYYFARVPEIDAVGTEVARVLATSKDTGVNADVYYT 3357

Query: 62   IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121
            I                           F ID +SG +     LD E+   Y + ++A D
Sbjct: 3358 I-------------------VGGNEHKKFEIDTKSGVVSIAEQLDYERAKDYFLTIQAID 3398

Query: 122  QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181
               P    L++ AT+++ ++D NDN P FS+ +Y  S+ ED    +   + ++ A D D 
Sbjct: 3399 GGVP---PLTNHATVNITVLDSNDNAPMFSQASYRASIREDAKAGEK--VVQVFANDLDS 3453

Query: 182  GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
              N  + Y+I  G+ Q QF+IDS SG ++++  LD EQ+ SY L + A+D G P+ SN  
Sbjct: 3454 NENGQVSYSIERGDRQKQFTIDSQSGQITVLAPLDREQIASYVLEVHAKDNGIPTLSNYV 3513

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
             + I + D NDN P F  + +   V E+ P+GY++++    DAD   NA   YT   +  
Sbjct: 3514 IVNIEVIDANDNPPLFAQNNYTTVVQEDKPLGYAVLKFTVTDADAEPNA-APYTFDFR-- 3570

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
            +GN      ++ + G + T+ +     + KY L +   D G PP  + A           
Sbjct: 3571 SGNEGDAFRLE-QDGTLRTATKFSNRVKDKYLLHIRVFDNGSPPLYSDAWVLVKIIEESQ 3629

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEI 403
                    +  +    DE PG  +  + A+D D+ + L Y +
Sbjct: 3630 YPPVITLLEININSYMDEYPGGVIGKVHASDKDQYDTLQYSL 3671



 Score =  167 bits (406), Expect = 4e-39
 Identities = 158/580 (27%), Positives = 262/580 (45%), Gaps = 59/580 (10%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + +LD ND +P+F   +YEA+V E      ++L + A D D+G N E+ Y+    T    
Sbjct: 196 VTILDTNDLNPLFYPTEYEATVTEDTPVHKSILKVSAEDADLGTNGEIYYSFAEKT---- 251

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS--PVSD 128
                            + F +   SG +     L   +   Y + V+A D+ +   ++ 
Sbjct: 252 -----------------EQFAVHPVSGVVTLTRPLRYVERPLYELTVQARDRGALYRMTP 294

Query: 129 RLSSTA-TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
           R S+   TIHV  +  N + P+ S +     + E +  ++    A ++  D D G +  I
Sbjct: 295 RASNARLTIHVRQV--NLHAPEISVR----HLPEILEHSNADTYAIVRVLDRDTGPHGEI 348

Query: 188 R-YAIIGGNTQMQFSIDSLS--GDVSL--VKTLDYEQV-RSYRLVIRAQDGGSPSRSNTT 241
               I+ G+    F +  L   G+ S+  +K LD E   + Y L +RA D G+P R +  
Sbjct: 349 ASLEIVAGDPDGHFRVRPLPTPGEYSIQVLKLLDREAAPQGYNLTLRAVDRGTPPRFSYK 408

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
            + +++ D+NDNAP F T ++   V E  P+   ++R++  DAD+G NA +   +     
Sbjct: 409 SVPVHLADLNDNAPIFSTEIYDVKVPETAPVNSPVIRLKVSDADQGKNALVFLEIVG--- 465

Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD--PPRSATATXXXXXXXX 359
            GN      I+  +G +YT+  LD ET+A Y L V+A D G+    + ++A         
Sbjct: 466 -GNEGGEFYINADTGMLYTAVPLDAETKAFYTLTVSAVDQGNAGTRKQSSAKVKIYVIDT 524

Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG 419
                 F   +  V L E+EP GT V  + A D D     +   +  N + R      + 
Sbjct: 525 NDNDPEFEKSEMLVYLDENEPAGTSVCKVVARDKDSGENAYISYSIDNIK-RVPFEIDHF 583

Query: 420 RGLITVAQPLDFK-QERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYT 475
            G++   Q LD++  +R Y+L V A D G    R     ++I + + N+  P FE     
Sbjct: 584 SGVVKTKQLLDYETMKREYLLHVRANDWGLPYRRQSEIQLRIKLRNVNDNRPQFEKIDCV 643

Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
             V     +GT ++ VSA D D G N  ITY + S        + D  F ++P +G ++ 
Sbjct: 644 GHVSRYVQVGTEIITVSAIDFDAG-NI-ITYRIVSG------GNADGCFALDPTSGVLSV 695

Query: 536 N-KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
              L D +T    ++ VTA DG     +D   + I +V+V
Sbjct: 696 ACDLSDLKTQE-MIVNVTATDG--THFADVNTLRIHLVNV 732



 Score =  113 bits (271), Expect = 9e-23
 Identities = 102/342 (29%), Positives = 149/342 (43%), Gaps = 35/342 (10%)

Query: 4    PFCIHQQIN--VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
            P   H  +N  VLD ND++P+F    Y AS+RE A +G  V+ + A D D  +N +V Y+
Sbjct: 3403 PLTNHATVNITVLDSNDNAPMFSQASYRASIREDAKAGEKVVQVFANDLDSNENGQVSYS 3462

Query: 62   IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121
            IE    D                  Q  F ID +SG +   A LDRE++A Y + V A D
Sbjct: 3463 IE--RGDR-----------------QKQFTIDSQSGQITVLAPLDREQIASYVLEVHAKD 3503

Query: 122  QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181
               P    LS+   +++ +ID NDN P F++  YT  V ED  +     + K   TDAD 
Sbjct: 3504 NGIPT---LSNYVIVNIEVIDANDNPPLFAQNNYTTVVQEDKPL--GYAVLKFTVTDADA 3558

Query: 182  GANSA-IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240
              N+A   +    GN    F ++   G +             Y L IR  D GSP   + 
Sbjct: 3559 EPNAAPYTFDFRSGNEGDAFRLEQ-DGTLRTATKFSNRVKDKYLLHIRVFDNGSPPLYSD 3617

Query: 241  TQLLINIRDVNDNAPRF-YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
              +L+ I + +   P      +   S  +  P G  I +V A D D+    + +   T  
Sbjct: 3618 AWVLVKIIEESQYPPVITLLEININSYMDEYP-GGVIGKVHASDKDQYDTLQYSLVPTSP 3676

Query: 300  DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341
                N DL   ID   G +    +LD     +Y++ V+ TDG
Sbjct: 3677 S-RPNTDL-FQIDKLDGTLVALPRLD---IGEYRVNVSVTDG 3713



 Score =  100 bits (240), Expect = 5e-19
 Identities = 104/375 (27%), Positives = 164/375 (43%), Gaps = 37/375 (9%)

Query: 438  VLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA--SVFED-APIGTTVLVVSAT 494
            ++TVSA D    +   ++   I    N    F   P +   SV  D + + T  ++V+ T
Sbjct: 656  IITVSAIDFDAGN---IITYRIVSGGNADGCFALDPTSGVLSVACDLSDLKTQEMIVNVT 712

Query: 495  DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT---V 551
             +D G +     +L   + N   A   Q  ++  +TG         R+T     LT    
Sbjct: 713  ATD-GTHFADVNTLRIHLVNVKRAQGPQSKLLTDETGGFEC-----RDTGVARRLTEAIA 766

Query: 552  TARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG 611
            +A    + S  D   +  S    N + P F        + E A +G  ++++ A D D+G
Sbjct: 767  SAEKNNMRSSEDEYSMMPSRYGENVHAPEFLDFPNEIRVNESAPIGFVLARLAARDRDLG 826

Query: 612  LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671
             NG++ Y +   D  +  F IDP +G +R    LDRE    + L     D G P +S++ 
Sbjct: 827  YNGKLVYGISAGD-SDSVFGIDPDTGELRLIGRLDREREDEYFLNITVYDLGKPQKSASR 885

Query: 672  IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD 731
            ++ + + D+ND+ P FE    +F +SE +  GT I      D D G NA V YS+    D
Sbjct: 886  MLAVSVLDVNDNAPKFEKALASFRVSEAALNGTIIFRANTTDADLGENAQVAYSLV--TD 943

Query: 732  SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA--------------SPPLWND 777
            ++ F ++   G     L     LD E  +  YEL IRA               +P L+++
Sbjct: 944  TSDFRVDRTTG----VLTVFGKLDRER-QSSYELRIRATDKNGGNDKGEPDFDNPALYSE 998

Query: 778  VRVEILVTDVNDNAP 792
              V + V DVNDNAP
Sbjct: 999  ALVRVSVDDVNDNAP 1013



 Score = 77.8 bits (183), Expect = 4e-12
 Identities = 78/307 (25%), Positives = 133/307 (43%), Gaps = 30/307 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +I V+D ND+ P FE  +    + E   +GT+V  + A D+D G+NA + Y+I+ +    
Sbjct: 518 KIYVIDTNDNDPEFEKSEMLVYLDENEPAGTSVCKVVARDKDSGENAYISYSIDNIK--- 574

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSD 128
                            +  F ID  SG + T+  LD E + R Y + V+A D   P   
Sbjct: 575 -----------------RVPFEIDHFSGVVKTKQLLDYETMKREYLLHVRANDWGLPY-- 615

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
           R  S   + + + + NDN PQF +      V   + V     I  + A D D G  + I 
Sbjct: 616 RRQSEIQLRIKLRNVNDNRPQFEKIDCVGHVSRYVQV--GTEIITVSAIDFDAG--NIIT 671

Query: 189 YAII-GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL-LIN 246
           Y I+ GGN    F++D  SG +S+   L   + +   + + A DG   +  NT ++ L+N
Sbjct: 672 YRIVSGGNADGCFALDPTSGVLSVACDLSDLKTQEMIVNVTATDGTHFADVNTLRIHLVN 731

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVR-VQAYDADEGVNAELTYTMTDKDYTGNV 305
           ++       +  T         +  +   +   + + + +   ++E  Y+M    Y  NV
Sbjct: 732 VKRAQGPQSKLLTDETGGFECRDTGVARRLTEAIASAEKNNMRSSEDEYSMMPSRYGENV 791

Query: 306 DLPITID 312
             P  +D
Sbjct: 792 HAPEFLD 798



 Score = 46.8 bits (106), Expect = 0.009
 Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 4/47 (8%)

Query: 1537 CTCEAGRVGPQC---VSACELGPCGAAR-CVPDQTPKGYSCACEPGY 1579
            C+C+ G  G  C   ++ C  GPC   + C+PD + +GYSC C  G+
Sbjct: 3891 CSCKEGYAGTHCEIVINECARGPCPVFKVCIPDSSVQGYSCQCPEGF 3937


>UniRef50_Q14517 Cluster: Cadherin-related tumor suppressor homolog
            precursor; n=49; Euteleostomi|Rep: Cadherin-related tumor
            suppressor homolog precursor - Homo sapiens (Human)
          Length = 4590

 Score =  459 bits (1132), Expect = e-127
 Identities = 407/1378 (29%), Positives = 639/1378 (46%), Gaps = 137/1378 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND+SPVFE   YEA + E    G+ V+ ++A+D D G N +V Y+++       
Sbjct: 2799 IQVKDANDNSPVFESSPYEAFIVENLPGGSRVIQIRASDADSGTNGQVMYSLD------- 2851

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           V + F I+  +G + T   LD EK   Y + V A+D    +  +L
Sbjct: 2852 ---------QSQSVEVIESFAINMETGWITTLKELDHEKRDNYQIKVVASDHGEKI--QL 2900

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA-NSAIRY 189
            SSTA + V + D ND+ P+F+ + Y  +V ED       VIA +  TDAD    N  + Y
Sbjct: 2901 SSTAIVDVTVTDVNDSPPRFTAEIYKGTVSEDDP--QGGVIAILSTTDADSEEINRQVTY 2958

Query: 190  AIIGGNTQMQFSIDSLSGD--VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
             I GG+   QF+++++  +  V + K LD E+  +Y L I A DG   S++      + +
Sbjct: 2959 FITGGDPLGQFAVETIQNEWKVYVKKPLDREKRDNYLLTITATDGTFSSKAIVE---VKV 3015

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
             D NDN+P    +L+ +++ E+V  G  I+++ A DAD   NAE+TYT+      G+   
Sbjct: 3016 LDANDNSPVCEKTLYSDTIPEDVLPGKLIMQISATDADIRSNAEITYTLL-----GSGAE 3070

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
               ++P +G + TS  LDRE QA Y LLV ATDGG   R   A+              F 
Sbjct: 3071 KFKLNPDTGELKTSTPLDREEQAVYHLLVRATDGGG--RFCQASIVVTLEDVNDNAPEFS 3128

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITV 425
               Y + + E+  PGT +  + ATDAD   + ++ Y +   +  G+FSI   +G  +I +
Sbjct: 3129 ADPYAITVFENTEPGTLLTRVQATDADAGLNRKILYSLID-SADGQFSINELSG--IIQL 3185

Query: 426  AQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
             +PLD + +  Y L++ A D G     + T  V +++ D N+  PVFE   Y A+V ED 
Sbjct: 3186 EKPLDRELQAVYTLSLKAVDQGLPRRLTATGTVIVSVLDINDNPPVFEYREYGATVSEDI 3245

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
             +GT VL V A   D+  NA+ITYS+ S   NE    H + F I+ +TGA+   + LD E
Sbjct: 3246 LVGTEVLQVYAASRDIEANAEITYSIIS--GNE----HGK-FSIDSKTGAVFIIENLDYE 3298

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
            +   Y LTV A DGG PSLSD   V ++V D+NDN PVF Q  YT  I EDA++  SV  
Sbjct: 3299 SSHEYYLTVEATDGGTPSLSDVATVNVNVTDINDNTPVFSQDTYTTVISEDAVLEQSVIT 3358

Query: 603  VGATDADVGLNGRIHYELDPKDREEG-SFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
            V A DAD   N  IHY +   D  +G SF IDP  G ++  K LDRE+++ + L   A D
Sbjct: 3359 VMADDADGPSNSHIHYSI--IDGNQGSSFTIDPVRGEVKVTKLLDRETISGYTLTVQASD 3416

Query: 662  GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA- 720
             G+PP+ +T  V+I + D+ND+ PVF     +  I EN P+G ++ ++   D D   N  
Sbjct: 3417 NGSPPRVNTTTVNIDVSDVNDNAPVFSRGNYSVIIQENKPVGFSVLQLVVTDEDSSHNGP 3476

Query: 721  VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRV 780
               ++I  G+D  +F +  +     +  +   + D+   + K   V     P L +   +
Sbjct: 3477 PFFFTIVTGNDEKAFEVNPQGVLLTSSAIKRKEKDHYLLQVK---VADNGKPQLSSLTYI 3533

Query: 781  EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLI 840
            +I V + +   P +   +I   +  + +  G  G++ A D DV D L Y  L     NL 
Sbjct: 3534 DIRVIEESIYPPAILPLEIFITSSGEEYSGGVIGKIHATDQDVYDTLTYS-LDPQMDNLF 3592

Query: 841  LLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRL 900
             ++ T G +    +L+        + VSVTDG     A + + +R +T+EML ++I +R 
Sbjct: 3593 SVSSTGGKLIAHKKLDIG---QYLLNVSVTDGKFTTVADITVHIRQVTQEMLNHTIAIRF 3649

Query: 901  NDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEV 960
             ++T E+F+      F   L  I+   + +I I S+Q         L+V     +P    
Sbjct: 3650 ANLTPEEFVGDYWRNFQRALRNILGVRRNDIQIVSLQSSEPHPH--LDVLLFVEKPG--- 3704

Query: 961  GVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFG 1020
                  S   S   L  ++    T +  +  V++L     +C    C  ++ C   +   
Sbjct: 3705 ------SAQISTKQLLHKINSSVTDIEEIIGVRILNVFQKLCAGLDC-PWKFCDEKVSVD 3757

Query: 1021 NASGFVNSDSVL-FRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQC 1079
             +    +S + L F       +  C C EG     C  +     CE D     C  GS+C
Sbjct: 3758 ESVMSTHSTARLSFVTPRHHRAAVCLCKEG----RCPPV--HHGCEDDP----CPEGSEC 3807

Query: 1080 VA---RREGGILCQGCSIDAAYTTAVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQ 1136
            V+     +   +C          ++   L   S+ V   LT    K   ++ ++L+  T 
Sbjct: 3808 VSDPWEEKHTCVCPSGRFGQCPGSSSMTLTGNSY-VKYRLTENENKLEMKLTMRLR--TY 3864

Query: 1137 TTSGLLLYNGRYNERHDFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEG-NVGDGS 1195
            +T  +++    Y    D+  LE+     GR     L++ F  G G   ++V+   V DG 
Sbjct: 3865 STHAVVM----YARGTDYSILEI---HHGR-----LQYKFDCGSGPGIVSVQSIQVNDGQ 3912

Query: 1196 WHTVEIEYFNRTITMILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRF 1255
            WH V +E       ++L   D+V + +G A   LK                  T     +
Sbjct: 3913 WHAVALEVNGNYARLVL---DQVHTASGTAPGTLK------------------TLNLDNY 3951

Query: 1256 LDLTGPLQIGGLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNS------YVADNGTLA- 1308
            +   G ++  G  +   S QV N  F GC+   Y++ + + LNS      ++ ++  ++ 
Sbjct: 3952 VFFGGHIRQQGTRH-GRSPQVGN-GFRGCMDSIYLNGQELPLNSKPRSYAHIEESVDVSP 4009

Query: 1309 GC-PEKRSRCSSAPCYNGAECS-DLWDTYICDCKEGHTGKDCADSTGP----PWRFGG 1360
            GC       C+S PC NG  C+      Y C C   + G  C  S  P    P  +GG
Sbjct: 4010 GCFLTATEDCASNPCQNGGVCNPSPAGGYYCKCSALYIGTHCEISVNPCSSNPCLYGG 4067



 Score =  403 bits (992), Expect = e-110
 Identities = 281/880 (31%), Positives = 449/880 (51%), Gaps = 54/880 (6%)

Query: 3    VPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
            V FC    I + D ND++P F   +YE ++   A+ GT+V+   A+D D G NA++ Y I
Sbjct: 2580 VAFCTVNVI-LTDDNDNAPQFRATKYEVNIGSSAAKGTSVVK-SASDADEGSNADITYAI 2637

Query: 63   ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122
            E   AD+                V++   I+  SG + T+ SL   +   +T  V+A D 
Sbjct: 2638 E---ADS--------------ESVKENLEINKLSGVITTKESLIGLENEFFTFFVRAVDN 2680

Query: 123  ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
             SP  +   S   ++V I+      P+FSE  YT +V ED+ V     I  I+A  +   
Sbjct: 2681 GSPSKE---SVVLVYVKILPPEMQLPKFSEPFYTFTVSEDVPV--GTEIDLIRAEHSGTV 2735

Query: 183  ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ-DGGSPSRSNTT 241
              S ++      N    F ID  SG + L K+LD+E  + Y+  I A+          + 
Sbjct: 2736 LYSLVKGNTPESNRDESFVIDRQSGRLKLEKSLDHETTKWYQFSILARCTQDDHEMVASV 2795

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
             + I ++D NDN+P F +S ++  + EN+P G  +++++A DAD G N ++ Y++ D+  
Sbjct: 2796 DVSIQVKDANDNSPVFESSPYEAFIVENLPGGSRVIQIRASDADSGTNGQVMYSL-DQSQ 2854

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR-SATATXXXXXXXXX 360
            +  V     I+  +GW+ T  +LD E +  YQ+ V A+D G+  + S+TA          
Sbjct: 2855 SVEVIESFAINMETGWITTLKELDHEKRDNYQIKVVASDHGEKIQLSSTAIVDVTVTDVN 2914

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNR-LHYEITGGNTRGRFSITSQ 417
                 F    Y+  ++ED+P G  +  L+ TDAD  E NR + Y ITGG+  G+F++ + 
Sbjct: 2915 DSPPRFTAEIYKGTVSEDDPQGGVIAILSTTDADSEEINRQVTYFITGGDPLGQFAVETI 2974

Query: 418  NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTAS 477
                 + V +PLD ++   Y+LT++ATD G  S  A+V++ + DAN+ +PV E   Y+ +
Sbjct: 2975 QNEWKVYVKKPLDREKRDNYLLTITATD-GTFSSKAIVEVKVLDANDNSPVCEKTLYSDT 3033

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            + ED   G  ++ +SATD+D+  NA+ITY+L        +    ++F +NP TG + T+ 
Sbjct: 3034 IPEDVLPGKLIMQISATDADIRSNAEITYTL--------LGSGAEKFKLNPDTGELKTST 3085

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
             LDRE  + Y L V A DGG         + +++ DVNDN P F    Y   + E+   G
Sbjct: 3086 PLDREEQAVYHLLVRATDGG--GRFCQASIVVTLEDVNDNAPEFSADPYAITVFENTEPG 3143

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
            T +++V ATDAD GLN +I Y L   D  +G F I+  SG+I+  K LDRE  A + L  
Sbjct: 3144 TLLTRVQATDADAGLNRKILYSL--IDSADGQFSINELSGIIQLEKPLDRELQAVYTLSL 3201

Query: 658  VAIDGGTPPQ-SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
             A+D G P + ++T  V + + DIND+PPVFE       +SE+  +GT + ++ A   D 
Sbjct: 3202 KAVDQGLPRRLTATGTVIVSVLDINDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDI 3261

Query: 717  GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPP 773
              NA + YSI  G++   FS++++ G+    +  + +LDYES   +Y L + A    +P 
Sbjct: 3262 EANAEITYSIISGNEHGKFSIDSKTGA----VFIIENLDYESSH-EYYLTVEATDGGTPS 3316

Query: 774  LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRI 831
            L +   V + VTD+NDN PV           +D         V A DAD      + Y I
Sbjct: 3317 LSDVATVNVNVTDINDNTPVFSQDTYTTVISEDAVLEQSVITVMADDADGPSNSHIHYSI 3376

Query: 832  LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            + GN  +   ++   G + ++  L+       T+ V  +D
Sbjct: 3377 IDGNQGSSFTIDPVRGEVKVTKLLDRETISGYTLTVQASD 3416



 Score =  320 bits (787), Expect = 3e-85
 Identities = 251/810 (30%), Positives = 390/810 (48%), Gaps = 69/810 (8%)

Query: 1    MSVPFCIHQQINVLDCND--HSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEV 58
            +S+    + ++ V+D N+  H PVF     + +V+E A  G+ V+T+ A D+D G++ E+
Sbjct: 1010 VSLSSTCYVEVEVVDVNENLHPPVFSSFVEKGTVKEDAPVGSLVMTVSAHDEDAGRDGEI 1069

Query: 59   EYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVK 118
             Y+I           D              VF+I   +G + T   LDRE  + Y + V 
Sbjct: 1070 RYSIR----------DGSGVG---------VFKIGEETGVIETSDRLDRESTSHYWLTVF 1110

Query: 119  ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178
            ATDQ       LSS   I++ + D NDN PQ SE  Y   + E+ S  D  V+ +I+A D
Sbjct: 1111 ATDQGVVP---LSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMEN-SPKDVSVV-QIEAFD 1165

Query: 179  ADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLV-KTLDYEQVRSYRLVIRAQDGGSPSR 237
             D  +N  + Y I  GN Q  FSI   +G ++   + LD EQ   + L +   D GSP +
Sbjct: 1166 PDSSSNDKLMYKITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGSPPK 1225

Query: 238  SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS-------IVRVQAYDADEGVNA 290
            S   ++++ I D NDN P+F    ++  + E              + RV A D DEG NA
Sbjct: 1226 STIARVIVKILDENDNKPQFLQKFYKIRLPEREKPDRERNARREPLYRVIATDKDEGPNA 1285

Query: 291  ELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL-VTATDGGDPPRSAT 349
            E++Y++ D    GN      I+P++G V +S +       +Y +L + A D G P +S+T
Sbjct: 1286 EISYSIED----GNEHGKFFIEPKTG-VVSSKRFS--AAGEYDILSIKAVDNGRPQKSST 1338

Query: 350  ATXXXXXXXXXXXXX---XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG 406
                               F    +   + E +P    +  ++         L ++ITGG
Sbjct: 1339 TRLHIEWISKPKQSLEPISFEESFFTFTVMESDPVAHMIGVISVEPPGIP--LWFDITGG 1396

Query: 407  NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYA 466
            N    F +    G G I VA+PLD +Q+  Y LTV ATD G  +    V I + D N++ 
Sbjct: 1397 NYDSHFDV--DKGTGTIIVAKPLDAEQKSNYNLTVEATD-GTTTILTQVFIKVIDTNDHR 1453

Query: 467  PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
            P F  + Y   + ED    T +L +SA D D     ++ Y+L S  S + ++   ++F +
Sbjct: 1454 PQFSTSKYEVVIPEDTAPETEILQISAVDQDE--KNKLIYTLQS--SRDPLSL--KKFRL 1507

Query: 527  NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586
            +P TG++ T++ LD E +S   LTV  RD  VP   +   + ++V D ND+ P F    Y
Sbjct: 1508 DPATGSLYTSEKLDHEAVSPAHLTVMVRDQDVPVKRNFARIVVNVSDTNDHAPWFTASSY 1567

Query: 587  TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD--REEGSFVIDPASGVIRTNKA 644
               + E A VG+ V QV A D D G N  + Y ++  +      SF+IDP  G I+T K 
Sbjct: 1568 KGRVYESAAVGSVVLQVTALDKDKGKNAEVLYSIESGNIGNIGNSFMIDPVLGSIKTAKE 1627

Query: 645  LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
            LDR + A +DL   A D G+PP S    V I +   +++ P F S   +  +SE   IG+
Sbjct: 1628 LDRSNQAEYDLMVKATDKGSPPMSEITSVRIFVTIADNASPKFTSKEYSVELSETVSIGS 1687

Query: 705  TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764
             +G + AH       + V Y IK G+  ++F +    G+    ++T   LD+E+    Y 
Sbjct: 1688 FVGMVTAHS-----QSSVVYEIKDGNTGDAFDINPHSGT----IITQKALDFET-LPIYT 1737

Query: 765  LVIRAAS-PPLWNDVRVEILVTDVNDNAPV 793
            L+I+  +   L  +  V + + D NDNAPV
Sbjct: 1738 LIIQGTNMAGLSTNTTVLVHLQDENDNAPV 1767



 Score =  319 bits (784), Expect = 6e-85
 Identities = 249/814 (30%), Positives = 394/814 (48%), Gaps = 56/814 (6%)

Query: 88   DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
            D F I+  SG ++T+ +LD E +  YT++++ T+ A      LS+  T+ V++ D+NDN 
Sbjct: 1711 DAFDINPHSGTIITQKALDFETLPIYTLIIQGTNMAG-----LSTNTTVLVHLQDENDNA 1765

Query: 148  PQFSEKTYTVSVDEDISV-----TDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI 202
            P F +  YT  + E  S+     TD  V   I+A DAD  +N+ + Y I+  +    F+I
Sbjct: 1766 PVFMQAEYTGLISESASINSVVLTDRNVPLVIRAADADKDSNALLVYHIVEPSVHTYFAI 1825

Query: 203  DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS--RSNTTQLLINIRDVNDNAPRFYTS 260
            DS +G +  V +LDYE+   +   ++  D G+P         + +++ D+ND  P F   
Sbjct: 1826 DSSTGAIHTVLSLDYEETSIFHFTVQVHDMGTPRLFAEYAANVTVHVIDINDCPPVFAKP 1885

Query: 261  LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT 320
            L++ S+      G  ++ V A DAD    ++L Y++T+    GN+    ++D ++G +  
Sbjct: 1886 LYEASLLLPTYKGVKVITVNATDADSSAFSQLIYSITE----GNIGEKFSMDYKTGALTV 1941

Query: 321  SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX-FMPGQYEVELAEDE 379
              Q   + +++Y+L V A+DG    R A  T               F    Y   + E+ 
Sbjct: 1942 --QNTTQLRSRYELTVRASDG----RFAGLTSVKINVKESKESHLKFTQDVYSAVVKENS 1995

Query: 380  PPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL 439
                 +  +TA  +  +  L Y I   N   RF I+  +G  L T   P D +Q+  + +
Sbjct: 1996 TEAETLAVITAIGSPINEPLFYHIL--NPDRRFKISRTSGV-LSTTGTPFDREQQEAFDV 2052

Query: 440  TVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497
             V   +    S  A  +V++ + D N+ APVF N PY A V  D  +G  +  V+A D D
Sbjct: 2053 VVEVIEEHKPSAVAHVVVKVIVEDQNDNAPVFVNLPYYAVVKVDTEVGHVIRYVTAVDRD 2112

Query: 498  VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG-YLLTVTARDG 556
             G N ++ Y L           H + F I P  G I+  K  + +T++  YL+TV A+DG
Sbjct: 2113 SGRNGEVHYYLKE---------HHEHFQIGP-LGEISLKKQFELDTLNKEYLVTVVAKDG 2162

Query: 557  GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616
            G P+ S    V I+V+  N   PVF++  Y+A I E   V + V  V A   + GL  ++
Sbjct: 2163 GNPAFSAEVIVPITVM--NKAMPVFEKPFYSAEIAESIQVHSPVVHVQANSPE-GL--KV 2217

Query: 617  HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676
             Y +   D     F I+  +GVI     LD E+   + L   A D  T   +  V V I 
Sbjct: 2218 FYSITDGD-PFSQFTINFNTGVINVIAPLDFEAHPAYKLSIRATDSLTGAHAE-VFVDII 2275

Query: 677  IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736
            ++DIND+PPVF        +SE S IGT++ ++RA D D  PN  + Y + G    +   
Sbjct: 2276 VDDINDNPPVFAQQSYAVTLSEASVIGTSVVQVRATDSDSEPNRGISYQMFGNHSKSHDH 2335

Query: 737  LETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPV 793
                  +    L+    LDYE  R ++ + +RA     P L +DV V + VTD+N N P+
Sbjct: 2336 FHVDSSTGLISLLR--TLDYEQSR-QHTIFVRAVDGGMPTLSSDVIVTVDVTDLNGNPPL 2392

Query: 794  MKDFQIIFNNYKDCFPVGPFGR-VPAYDADVT--DKLQYRILSGNNANLILLNETTGSMT 850
             +  QI      +  P G F   V AYDAD +  DKLQY ILSGN+    +++  TG +T
Sbjct: 2393 FEQ-QIYEARISEHAPHGHFVTCVKAYDADSSDIDKLQYSILSGNDHKHFVIDSATGIIT 2451

Query: 851  LSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884
            LS      +    ++ +SV+DGV      + ++V
Sbjct: 2452 LSNLHRHALKPFYSLNLSVSDGVFRSSTQVHVTV 2485



 Score =  312 bits (766), Expect = 9e-83
 Identities = 259/893 (29%), Positives = 413/893 (46%), Gaps = 93/893 (10%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++++ D ND+ P F    Y   VRE    GT ++ L+A D D+G++ +V Y++       
Sbjct: 914  KVSLEDVNDNPPTFIPPNYRVKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSL------- 966

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            L+  +               F +D  SGA+     LD EK   Y + V+A D+  PVS  
Sbjct: 967  LDHGEGN-------------FDVDKLSGAVRIVQQLDFEKKQVYNLTVRAKDKGKPVS-- 1011

Query: 130  LSSTATIHVNIIDDNDNY--PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
            LSST  + V ++D N+N   P FS      +V ED  V    ++  + A D D G +  I
Sbjct: 1012 LSSTCYVEVEVVDVNENLHPPVFSSFVEKGTVKEDAPV--GSLVMTVSAHDEDAGRDGEI 1069

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            RY+I  G+    F I   +G +     LD E    Y L + A D G    S+  ++ I +
Sbjct: 1070 RYSIRDGSGVGVFKIGEETGVIETSDRLDRESTSHYWLTVFATDQGVVPLSSFIEIYIEV 1129

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
             DVNDNAP+    ++   + EN P   S+V+++A+D D   N +L Y +T    +GN   
Sbjct: 1130 EDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSSSNDKLMYKIT----SGNPQG 1185

Query: 308  PITIDPRSGWV-YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
              +I P++G +  TS +LDRE Q ++ L VT TD G PP+S  A               F
Sbjct: 1186 FFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGSPPKSTIARVIVKILDENDNKPQF 1245

Query: 367  MPGQYEVELAEDEPPG-------TPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQ 417
            +   Y++ L E E P         P+  + ATD DE  +  + Y I  GN  G+F I  +
Sbjct: 1246 LQKFYKIRLPEREKPDRERNARREPLYRVIATDKDEGPNAEISYSIEDGNEHGKFFIEPK 1305

Query: 418  NGRGLITVAQPLDFKQERRY-VLTVSATDSGGRSDTAMVQINI----TDANNYAPV-FEN 471
             G     V     F     Y +L++ A D+G    ++  +++I        +  P+ FE 
Sbjct: 1306 TG-----VVSSKRFSAAGEYDILSIKAVDNGRPQKSSTTRLHIEWISKPKQSLEPISFEE 1360

Query: 472  APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
            + +T +V E  P+   + V+S     + +   IT             ++D  F ++  TG
Sbjct: 1361 SFFTFTVMESDPVAHMIGVISVEPPGIPLWFDIT-----------GGNYDSHFDVDKGTG 1409

Query: 532  AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
             I   K LD E  S Y LTV A DG    L   T V I V+D ND+ P F    Y   I 
Sbjct: 1410 TIIVAKPLDAEQKSNYNLTVEATDGTTTIL---TQVFIKVIDTNDHRPQFSTSKYEVVIP 1466

Query: 592  EDALVGTSVSQVGATDADVGLNGRIHYEL----DPKDREEGSFVIDPASGVIRTNKALDR 647
            ED    T + Q+ A D D     ++ Y L    DP   ++  F +DPA+G + T++ LD 
Sbjct: 1467 EDTAPETEILQISAVDQDE--KNKLIYTLQSSRDPLSLKK--FRLDPATGSLYTSEKLDH 1522

Query: 648  ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
            E+V+   L  +  D   P + +   + + + D ND  P F +      + E++ +G+ + 
Sbjct: 1523 EAVSPAHLTVMVRDQDVPVKRNFARIVVNVSDTNDHAPWFTASSYKGRVYESAAVGSVVL 1582

Query: 708  EIRAHDPDEGPNAVVHYSIKG---GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764
            ++ A D D+G NA V YSI+    G+  NSF ++   GS K    T  +LD  S + +Y+
Sbjct: 1583 QVTALDKDKGKNAEVLYSIESGNIGNIGNSFMIDPVLGSIK----TAKELD-RSNQAEYD 1637

Query: 765  LVIRA---ASPPLWNDVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFPVGPF-GRVPA 818
            L+++A    SPP+     V I VT  ++ +P    K++ +      +   +G F G V A
Sbjct: 1638 LMVKATDKGSPPMSEITSVRIFVTIADNASPKFTSKEYSV---ELSETVSIGSFVGMVTA 1694

Query: 819  YDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            +       + Y I  GN  +   +N  +G++     L+     + T+ +  T+
Sbjct: 1695 HS---QSSVVYEIKDGNTGDAFDINPHSGTIITQKALDFETLPIYTLIIQGTN 1744



 Score =  300 bits (736), Expect = 4e-79
 Identities = 226/718 (31%), Positives = 356/718 (49%), Gaps = 44/718 (6%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDD--NDNY 147
            F I+  +G +   A LD E    Y + ++ATD  +       + A + V+II D  NDN 
Sbjct: 2230 FTINFNTGVINVIAPLDFEAHPAYKLSIRATDSLT------GAHAEVFVDIIVDDINDNP 2283

Query: 148  PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ--FSIDSL 205
            P F++++Y V++ E  SV    V+ +++ATD+D   N  I Y + G +++    F +DS 
Sbjct: 2284 PVFAQQSYAVTLSE-ASVIGTSVV-QVRATDSDSEPNRGISYQMFGNHSKSHDHFHVDSS 2341

Query: 206  SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265
            +G +SL++TLDYEQ R + + +RA DGG P+ S+   + +++ D+N N P F   +++  
Sbjct: 2342 TGLISLLRTLDYEQSRQHTIFVRAVDGGMPTLSSDVIVTVDVTDLNGNPPLFEQQIYEAR 2401

Query: 266  VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325
            +SE+ P G+ +  V+AYDAD     +L Y++     +GN      ID  +G +  S    
Sbjct: 2402 ISEHAPHGHFVTCVKAYDADSSDIDKLQYSI----LSGNDHKHFVIDSATGIITLSNLHR 2457

Query: 326  RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
               +  Y L ++ +DG    RS+T                F+  +YEVELAE+ P  T V
Sbjct: 2458 HALKPFYSLNLSVSDG--VFRSSTQV-HVTVIGGNLHSPAFLQNEYEVELAENAPLHTLV 2514

Query: 386  VTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV-- 441
            + +  TD D      + Y I     + RF I   N RG I   + LD +     V++V  
Sbjct: 2515 MEVKTTDGDSGIYGHVTYHIVNDFAKDRFYI---NERGQIFTLEKLDRETPAEKVISVRL 2571

Query: 442  SATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501
             A D+GG+     V + +TD N+ AP F    Y  ++   A  GT+V V SA+D+D G N
Sbjct: 2572 MAKDAGGKVAFCTVNVILTDDNDNAPQFRATKYEVNIGSSAAKGTSV-VKSASDADEGSN 2630

Query: 502  AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL 561
            A ITY++  E  +E+V    +   IN  +G ITT + L       +   V A D G PS 
Sbjct: 2631 ADITYAI--EADSESV---KENLEINKLSGVITTKESLIGLENEFFTFFVRAVDNGSPSK 2685

Query: 562  SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621
                 V + ++      P F +  YT  + ED  VGT +  + A  +   L   +     
Sbjct: 2686 ESVVLVYVKILPPEMQLPKFSEPFYTFTVSEDVPVGTEIDLIRAEHSGTVLYSLVKGNTP 2745

Query: 622  PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA-IDGGTPPQSSTVIVHIKIEDI 680
              +R+E SFVID  SG ++  K+LD E+   +    +A          ++V V I+++D 
Sbjct: 2746 ESNRDE-SFVIDRQSGRLKLEKSLDHETTKWYQFSILARCTQDDHEMVASVDVSIQVKDA 2804

Query: 681  NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL--E 738
            ND+ PVFES     +I EN P G+ + +IRA D D G N  V YS+   D S S  +   
Sbjct: 2805 NDNSPVFESSPYEAFIVENLPGGSRVIQIRASDADSGTNGQVMYSL---DQSQSVEVIES 2861

Query: 739  TRQGSDKAELVTMVDLDYESPRKKYELVIRAASP----PLWNDVRVEILVTDVNDNAP 792
                 +   + T+ +LD+E  R  Y++ + A+       L +   V++ VTDVND+ P
Sbjct: 2862 FAINMETGWITTLKELDHEK-RDNYQIKVVASDHGEKIQLSSTAIVDVTVTDVNDSPP 2918



 Score =  299 bits (735), Expect = 5e-79
 Identities = 254/880 (28%), Positives = 400/880 (45%), Gaps = 78/880 (8%)

Query: 17   NDHSPVFEMQQYEA-SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDA 75
            N H P F         V+E    G++V+ + +TD D G N ++ Y +     D+      
Sbjct: 710  NAHIPQFRSTLPTGIQVKENQPVGSSVIFMNSTDLDTGFNGKLVYAVSGGNEDSC----- 764

Query: 76   XXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTAT 135
                          F ID  +G L   + LDRE   +YT+ +   D   P   + ++   
Sbjct: 765  --------------FMIDMETGMLKILSPLDRETTDKYTLNITVYDLGIP---QKAAWRL 807

Query: 136  IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195
            +HV ++D NDN P+F +++Y V V ED  V  +  I +++ATD D+G N  + Y+I+   
Sbjct: 808  LHVVVVDANDNPPEFLQESYFVEVSEDKEV--HSEIIQVEATDKDLGPNGHVTYSILTDT 865

Query: 196  TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG--SPSRSNTTQLLINIRDVNDN 253
                FSIDS++G V++ + LD E    + L I A+D     P   +T  + +++ DVNDN
Sbjct: 866  D--TFSIDSVTGVVNIARPLDRELQHEHSLKIEARDQAREEPQLFSTVVVKVSLEDVNDN 923

Query: 254  APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313
             P F    ++  V E++P G  I+ ++A+D D G + ++ Y++ D    GN D    +D 
Sbjct: 924  PPTFIPPNYRVKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSLLDHG-EGNFD----VDK 978

Query: 314  RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX---XFMPGQ 370
             SG V    QLD E +  Y L V A D G P   ++                   F    
Sbjct: 979  LSGAVRIVQQLDFEKKQVYNLTVRAKDKGKPVSLSSTCYVEVEVVDVNENLHPPVFSSFV 1038

Query: 371  YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
             +  + ED P G+ V+T++A D D   D  + Y I  G+  G F I  +   G+I  +  
Sbjct: 1039 EKGTVKEDAPVGSLVMTVSAHDEDAGRDGEIRYSIRDGSGVGVFKIGEET--GVIETSDR 1096

Query: 429  LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
            LD +    Y LTV ATD G    S    + I + D N+ AP      Y   + E++P   
Sbjct: 1097 LDRESTSHYWLTVFATDQGVVPLSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKDV 1156

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKLLDRETMS 545
            +V+ + A D D   N ++ Y ++S        +    F I+P+TG I TT++ LDRE   
Sbjct: 1157 SVVQIEAFDPDSSSNDKLMYKITS-------GNPQGFFSIHPKTGLITTTSRKLDREQQD 1209

Query: 546  GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS------ 599
             ++L VT  D G P  S    V + ++D NDN+P F Q+ Y   + E             
Sbjct: 1210 EHILEVTVTDNGSPPKSTIARVIVKILDENDNKPQFLQKFYKIRLPEREKPDRERNARRE 1269

Query: 600  -VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
             + +V ATD D G N  I Y ++    E G F I+P +GV+ + +     +   +D+ ++
Sbjct: 1270 PLYRVIATDKDEGPNAEISYSIE-DGNEHGKFFIEPKTGVVSSKRF---SAAGEYDILSI 1325

Query: 659  -AIDGGTPPQSSTVIVHIK-IEDINDS--PPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
             A+D G P +SST  +HI+ I     S  P  FE    TF + E+ P+   IG I     
Sbjct: 1326 KAVDNGRPQKSSTTRLHIEWISKPKQSLEPISFEESFFTFTVMESDPVAHMIGVISV--- 1382

Query: 715  DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL 774
             E P   + + I GG+  + F ++   G+    ++    LD E  +  Y L + A     
Sbjct: 1383 -EPPGIPLWFDITGGNYDSHFDVDKGTGT----IIVAKPLDAEQ-KSNYNLTVEATDGTT 1436

Query: 775  WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSG 834
                +V I V D ND+ P     +      +D  P     ++ A D D  +KL Y + S 
Sbjct: 1437 TILTQVFIKVIDTNDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQDEKNKLIYTLQSS 1496

Query: 835  N---NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
                +     L+  TGS+  S +L+      A + V V D
Sbjct: 1497 RDPLSLKKFRLDPATGSLYTSEKLDHEAVSPAHLTVMVRD 1536



 Score =  289 bits (709), Expect = 7e-76
 Identities = 211/673 (31%), Positives = 332/673 (49%), Gaps = 56/673 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ VLD ND+SPV E   Y  ++ E    G  ++ + ATD DI  NAE+ YT+       
Sbjct: 3012 EVKVLDANDNSPVCEKTLYSDTIPEDVLPGKLIMQISATDADIRSNAEITYTL------- 3064

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                              + F+++  +G L T   LDRE+ A Y +LV+ATD        
Sbjct: 3065 -------------LGSGAEKFKLNPDTGELKTSTPLDREEQAVYHLLVRATDGGGRFCQ- 3110

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
                A+I V + D NDN P+FS   Y ++V E  +     ++ +++ATDAD G N  I Y
Sbjct: 3111 ----ASIVVTLEDVNDNAPEFSADPYAITVFE--NTEPGTLLTRVQATDADAGLNRKILY 3164

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT-QLLINIR 248
            ++I  +   QFSI+ LSG + L K LD E    Y L ++A D G P R   T  +++++ 
Sbjct: 3165 SLI-DSADGQFSINELSGIIQLEKPLDRELQAVYTLSLKAVDQGLPRRLTATGTVIVSVL 3223

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            D+NDN P F    +  +VSE++ +G  +++V A   D   NAE+TY++     +GN    
Sbjct: 3224 DINDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEANAEITYSI----ISGNEHGK 3279

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
             +ID ++G V+    LD E+  +Y L V ATDGG P  S  AT              F  
Sbjct: 3280 FSIDSKTGAVFIIENLDYESSHEYYLTVEATDGGTPSLSDVATVNVNVTDINDNTPVFSQ 3339

Query: 369  GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
              Y   ++ED      V+T+ A DAD   ++ +HY I  GN    F+I     RG + V 
Sbjct: 3340 DTYTTVISEDAVLEQSVITVMADDADGPSNSHIHYSIIDGNQGSSFTIDPV--RGEVKVT 3397

Query: 427  QPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
            + LD +    Y LTV A+D+G   R +T  V I+++D N+ APVF    Y+  + E+ P+
Sbjct: 3398 KLLDRETISGYTLTVQASDNGSPPRVNTTTVNIDVSDVNDNAPVFSRGNYSVIIQENKPV 3457

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            G +VL +  TD D   N    +  +    N+     ++ F +NPQ G + T+  + R+  
Sbjct: 3458 GFSVLQLVVTDEDSSHNGP-PFFFTIVTGND-----EKAFEVNPQ-GVLLTSSAIKRKEK 3510

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP-VFKQQLYTANIMEDALVGTSVSQV 603
              YLL V   D G P LS  T ++I V++ +   P +   +++  +  E+   G  + ++
Sbjct: 3511 DHYLLQVKVADNGKPQLSSLTYIDIRVIEESIYPPAILPLEIFITSSGEE-YSGGVIGKI 3569

Query: 604  GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
             ATD DV     + Y LDP  + +  F +    G +  +K LD   +  + L  V++  G
Sbjct: 3570 HATDQDV--YDTLTYSLDP--QMDNLFSVSSTGGKLIAHKKLD---IGQY-LLNVSVTDG 3621

Query: 664  TPPQSSTVIVHIK 676
                 + + VHI+
Sbjct: 3622 KFTTVADITVHIR 3634



 Score =  289 bits (708), Expect = 1e-75
 Identities = 258/883 (29%), Positives = 412/883 (46%), Gaps = 74/883 (8%)

Query: 13   VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72
            V+D ND+ P F  + Y   V E     + ++ ++ATD+D+G N  V Y+I     DT   
Sbjct: 812  VVDANDNPPEFLQESYFVEVSEDKEVHSEIIQVEATDKDLGPNGHVTYSI---LTDT--- 865

Query: 73   EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132
                           D F ID  +G +     LDRE    +++ ++A DQA     +L S
Sbjct: 866  ---------------DTFSIDSVTGVVNIARPLDRELQHEHSLKIEARDQARE-EPQLFS 909

Query: 133  TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192
            T  + V++ D NDN P F    Y V V ED+   +  VI  ++A D D+G +  +RY+++
Sbjct: 910  TVVVKVSLEDVNDNPPTFIPPNYRVKVREDL--PEGTVIMWLEAHDPDLGQSGQVRYSLL 967

Query: 193  GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP-SRSNTTQLLINIRDVN 251
              + +  F +D LSG V +V+ LD+E+ + Y L +RA+D G P S S+T  + + + DVN
Sbjct: 968  -DHGEGNFDVDKLSGAVRIVQQLDFEKKQVYNLTVRAKDKGKPVSLSSTCYVEVEVVDVN 1026

Query: 252  DNA-PRFYTSLFQE-SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            +N  P  ++S  ++ +V E+ P+G  ++ V A+D D G + E+ Y++ D    G      
Sbjct: 1027 ENLHPPVFSSFVEKGTVKEDAPVGSLVMTVSAHDEDAGRDGEIRYSIRDGSGVG----VF 1082

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             I   +G + TS +LDRE+ + Y L V ATD G  P S+                     
Sbjct: 1083 KIGEETGVIETSDRLDRESTSHYWLTVFATDQGVVPLSSFIEIYIEVEDVNDNAPQTSEP 1142

Query: 370  QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
             Y  E+ E+ P    VV + A D D   +++L Y+IT GN +G FSI  + G  + T ++
Sbjct: 1143 VYYPEIMENSPKDVSVVQIEAFDPDSSSNDKLMYKITSGNPQGFFSIHPKTGL-ITTTSR 1201

Query: 428  PLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE-DAP- 483
             LD +Q+  ++L V+ TD+G   +S  A V + I D N+  P F    Y   + E + P 
Sbjct: 1202 KLDREQQDEHILEVTVTDNGSPPKSTIARVIVKILDENDNKPQFLQKFYKIRLPEREKPD 1261

Query: 484  -----IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
                     +  V ATD D G NA+I+YS+  E  NE    H  +F I P+TG +++ + 
Sbjct: 1262 RERNARREPLYRVIATDKDEGPNAEISYSI--EDGNE----HG-KFFIEPKTGVVSSKRF 1314

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD--VNDNEPV-FKQQLYTANIMEDAL 595
                     +L++ A D G P  S TT + I  +       EP+ F++  +T  +ME   
Sbjct: 1315 SAAGEYD--ILSIKAVDNGRPQKSSTTRLHIEWISKPKQSLEPISFEESFFTFTVMESDP 1372

Query: 596  VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655
            V   +  +      + L     +++      +  F +D  +G I   K LD E  + ++L
Sbjct: 1373 VAHMIGVISVEPPGIPL----WFDI-TGGNYDSHFDVDKGTGTIIVAKPLDAEQKSNYNL 1427

Query: 656  KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
               A DG T   +    V IK+ D ND  P F +      I E++   T I +I A D D
Sbjct: 1428 TVEATDGTT---TILTQVFIKVIDTNDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQD 1484

Query: 716  EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE--SPRKKYELVIRAASPP 773
            E  N ++ Y+++   D  S   + R       L T   LD+E  SP     +V     P 
Sbjct: 1485 E-KNKLI-YTLQSSRDPLSLK-KFRLDPATGSLYTSEKLDHEAVSPAHLTVMVRDQDVPV 1541

Query: 774  LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRI 831
              N  R+ + V+D ND+AP           Y+         +V A D D     ++ Y I
Sbjct: 1542 KRNFARIVVNVSDTNDHAPWFTASSYKGRVYESAAVGSVVLQVTALDKDKGKNAEVLYSI 1601

Query: 832  LSGNNANL---ILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
             SGN  N+    +++   GS+  + +L+ +      + V  TD
Sbjct: 1602 ESGNIGNIGNSFMIDPVLGSIKTAKELDRSNQAEYDLMVKATD 1644



 Score =  272 bits (666), Expect = 1e-70
 Identities = 213/716 (29%), Positives = 326/716 (45%), Gaps = 46/716 (6%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            F +D  +G ++    LD E+ + Y + V+ATD  + +  +      + + +ID ND+ PQ
Sbjct: 1402 FDVDKGTGTIIVAKPLDAEQKSNYNLTVEATDGTTTILTQ------VFIKVIDTNDHRPQ 1455

Query: 150  FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQM---QFSIDSLS 206
            FS   Y V + ED +      I +I A D D    + + Y +      +   +F +D  +
Sbjct: 1456 FSTSKYEVVIPEDTAPETE--ILQISAVDQD--EKNKLIYTLQSSRDPLSLKKFRLDPAT 1511

Query: 207  GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266
            G +   + LD+E V    L +  +D   P + N  ++++N+ D ND+AP F  S ++  V
Sbjct: 1512 GSLYTSEKLDHEAVSPAHLTVMVRDQDVPVKRNFARIVVNVSDTNDHAPWFTASSYKGRV 1571

Query: 267  SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326
             E+  +G  +++V A D D+G NAE+ Y++ +    GN+     IDP  G + T+ +LDR
Sbjct: 1572 YESAAVGSVVLQVTALDKDKGKNAEVLYSI-ESGNIGNIGNSFMIDPVLGSIKTAKELDR 1630

Query: 327  ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386
              QA+Y L+V ATD G PP S   +              F   +Y VEL+E    G+ V 
Sbjct: 1631 SNQAEYDLMVKATDKGSPPMSEITSVRIFVTIADNASPKFTSKEYSVELSETVSIGSFVG 1690

Query: 387  TLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446
             +T   A   + + YEI  GNT   F I   +  G I   + LDF+    Y L +  T+ 
Sbjct: 1691 MVT---AHSQSSVVYEIKDGNTGDAFDINPHS--GTIITQKALDFETLPIYTLIIQGTNM 1745

Query: 447  GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV-------LVVSATDSDVG 499
             G S    V +++ D N+ APVF  A YT  + E A I + V       LV+ A D+D  
Sbjct: 1746 AGLSTNTTVLVHLQDENDNAPVFMQAEYTGLISESASINSVVLTDRNVPLVIRAADADKD 1805

Query: 500  INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
             NA + Y +      E   H    F I+  TGAI T   LD E  S +  TV   D G P
Sbjct: 1806 SNALLVYHIV-----EPSVH--TYFAIDSSTGAIHTVLSLDYEETSIFHFTVQVHDMGTP 1858

Query: 560  SL--SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617
             L      +V + V+D+ND  PVF + LY A+++     G  V  V ATDAD     ++ 
Sbjct: 1859 RLFAEYAANVTVHVIDINDCPPVFAKPLYEASLLLPTYKGVKVITVNATDADSSAFSQLI 1918

Query: 618  YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
            Y +   +  E  F +D  +G +         S   ++L   A DG     +S   V I +
Sbjct: 1919 YSITEGNIGE-KFSMDYKTGALTVQNTTQLRS--RYELTVRASDGRFAGLTS---VKINV 1972

Query: 678  EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL 737
            ++  +S   F  D  +  + ENS    T+  I A       N  + Y I   D    F +
Sbjct: 1973 KESKESHLKFTQDVYSAVVKENSTEAETLAVITA--IGSPINEPLFYHILNPD--RRFKI 2028

Query: 738  ETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPV 793
             +R     +   T  D + +        VI    P     V V+++V D NDNAPV
Sbjct: 2029 -SRTSGVLSTTGTPFDREQQEAFDVVVEVIEEHKPSAVAHVVVKVIVEDQNDNAPV 2083



 Score =  254 bits (621), Expect = 3e-65
 Identities = 229/798 (28%), Positives = 371/798 (46%), Gaps = 68/798 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ V D ND++PVF    Y A V+     G  +  + A D+D G+N EV Y ++      
Sbjct: 2071 KVIVEDQNDNAPVFVNLPYYAVVKVDTEVGHVIRYVTAVDRDSGRNGEVHYYLK------ 2124

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                +           ++  F +D          +L++E    Y V V A D  +P    
Sbjct: 2125 -EHHEHFQIGPLGEISLKKQFELD----------TLNKE----YLVTVVAKDGGNPA--- 2166

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             S+   + + ++  N   P F +  Y+  + E I V  +PV+  ++A   +      + Y
Sbjct: 2167 FSAEVIVPITVM--NKAMPVFEKPFYSAEIAESIQV-HSPVV-HVQANSPE---GLKVFY 2219

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            +I  G+   QF+I+  +G ++++  LD+E   +Y+L IRA D  + + +     +I + D
Sbjct: 2220 SITDGDPFSQFTINFNTGVINVIAPLDFEAHPAYKLSIRATDSLTGAHAEVFVDII-VDD 2278

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            +NDN P F    +  ++SE   IG S+V+V+A D+D   N  ++Y M   +++ + D   
Sbjct: 2279 INDNPPVFAQQSYAVTLSEASVIGTSVVQVRATDSDSEPNRGISYQMFG-NHSKSHD-HF 2336

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             +D  +G +     LD E   ++ + V A DGG P  S+                 F   
Sbjct: 2337 HVDSSTGLISLLRTLDYEQSRQHTIFVRAVDGGMPTLSSDVIVTVDVTDLNGNPPLFEQQ 2396

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
             YE  ++E  P G  V  + A DAD  +  +L Y I  GN    F I S  G  +IT++ 
Sbjct: 2397 IYEARISEHAPHGHFVTCVKAYDADSSDIDKLQYSILSGNDHKHFVIDSATG--IITLSN 2454

Query: 428  PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
                  +  Y L +S +D   RS T  V + +   N ++P F    Y   + E+AP+ T 
Sbjct: 2455 LHRHALKPFYSLNLSVSDGVFRSST-QVHVTVIGGNLHSPAFLQNEYEVELAENAPLHTL 2513

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
            V+ V  TD D GI   +TY + ++ + +       +F IN + G I T + LDRET +  
Sbjct: 2514 VMEVKTTDGDSGIYGHVTYHIVNDFAKD-------RFYIN-ERGQIFTLEKLDRETPAEK 2565

Query: 548  LLTVT--ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
            +++V   A+D G      T  V + + D NDN P F+   Y  NI   A  GTSV +  A
Sbjct: 2566 VISVRLMAKDAGGKVAFCT--VNVILTDDNDNAPQFRATKYEVNIGSSAAKGTSVVK-SA 2622

Query: 606  TDADVGLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            +DAD G N  I Y ++      + +  I+  SGVI T ++L             A+D G+
Sbjct: 2623 SDADEGSNADITYAIEADSESVKENLEINKLSGVITTKESLIGLENEFFTFFVRAVDNGS 2682

Query: 665  PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
            P + S V+V++KI       P F     TF +SE+ P+GT I  IRA    E    V++ 
Sbjct: 2683 PSKESVVLVYVKILPPEMQLPKFSEPFYTFTVSEDVPVGTEIDLIRA----EHSGTVLYS 2738

Query: 725  SIKGGD-DSN---SFSLETRQGSDKAELVTMVDLDYESPR-KKYELVIRAASPP--LWND 777
             +KG   +SN   SF ++ + G  K E      LD+E+ +  ++ ++ R       +   
Sbjct: 2739 LVKGNTPESNRDESFVIDRQSGRLKLEK----SLDHETTKWYQFSILARCTQDDHEMVAS 2794

Query: 778  VRVEILVTDVNDNAPVMK 795
            V V I V D NDN+PV +
Sbjct: 2795 VDVSIQVKDANDNSPVFE 2812



 Score =  216 bits (527), Expect = 8e-54
 Identities = 215/787 (27%), Positives = 334/787 (42%), Gaps = 88/787 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASV-------REGASSGTTVLTLKATDQDIGKNAEVEYTIE 63
            + +LD ND+ P F  + Y+  +       RE  +    +  + ATD+D G NAE+ Y+IE
Sbjct: 1233 VKILDENDNKPQFLQKFYKIRLPEREKPDRERNARREPLYRVIATDKDEGPNAEISYSIE 1292

Query: 64   LVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVL-VKATDQ 122
                                      F I+ ++G + ++          Y +L +KA D 
Sbjct: 1293 -------------------DGNEHGKFFIEPKTGVVSSKRF---SAAGEYDILSIKAVDN 1330

Query: 123  ASPVSDRLSSTATIHVNIIDDNDNYPQ---FSEKTYTVSVDEDISVTDNPVIAKIKATDA 179
              P   + SST  +H+  I       +   F E  +T +V E      +PV   I     
Sbjct: 1331 GRP---QKSSTTRLHIEWISKPKQSLEPISFEESFFTFTVMES-----DPVAHMIGVISV 1382

Query: 180  DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239
            +      + + I GGN    F +D  +G + + K LD EQ  +Y L + A DG   + + 
Sbjct: 1383 EP-PGIPLWFDITGGNYDSHFDVDKGTGTIIVAKPLDAEQKSNYNLTVEATDG---TTTI 1438

Query: 240  TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
             TQ+ I + D ND+ P+F TS ++  + E+      I+++ A D DE    +L YT+   
Sbjct: 1439 LTQVFIKVIDTNDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQDE--KNKLIYTLQSS 1496

Query: 300  DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
                ++     +DP +G +YTS +LD E  +   L V   D   P +   A         
Sbjct: 1497 RDPLSLK-KFRLDPATGSLYTSEKLDHEAVSPAHLTVMVRDQDVPVKRNFARIVVNVSDT 1555

Query: 360  XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRG-RFSITS 416
                  F    Y+  + E    G+ V+ +TA D D+       Y I  GN      S   
Sbjct: 1556 NDHAPWFTASSYKGRVYESAAVGSVVLQVTALDKDKGKNAEVLYSIESGNIGNIGNSFMI 1615

Query: 417  QNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPY 474
                G I  A+ LD   +  Y L V ATD G    S+   V+I +T A+N +P F +  Y
Sbjct: 1616 DPVLGSIKTAKELDRSNQAEYDLMVKATDKGSPPMSEITSVRIFVTIADNASPKFTSKEY 1675

Query: 475  TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
            +  + E   IG+ V +V+A        + + Y +    + +A       F INP +G I 
Sbjct: 1676 SVELSETVSIGSFVGMVTAHS-----QSSVVYEIKDGNTGDA-------FDINPHSGTII 1723

Query: 535  TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
            T K LD ET+  Y L +   +  +  LS  T V + + D NDN PVF Q  YT  I E A
Sbjct: 1724 TQKALDFETLPIYTLIIQGTN--MAGLSTNTTVLVHLQDENDNAPVFMQAEYTGLISESA 1781

Query: 595  LVGTSVSQ-------VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647
             + + V         + A DAD   N  + Y +  +      F ID ++G I T  +LD 
Sbjct: 1782 SINSVVLTDRNVPLVIRAADADKDSNALLVYHI-VEPSVHTYFAIDSSTGAIHTVLSLDY 1840

Query: 648  ESVATHDLKAVAIDGGTP----PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703
            E  +         D GTP      ++ V VH  + DIND PPVF        +   +  G
Sbjct: 1841 EETSIFHFTVQVHDMGTPRLFAEYAANVTVH--VIDINDCPPVFAKPLYEASLLLPTYKG 1898

Query: 704  TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY 763
              +  + A D D    + + YSI  G+    FS++ + G+   +  T +       R +Y
Sbjct: 1899 VKVITVNATDADSSAFSQLIYSITEGNIGEKFSMDYKTGALTVQNTTQL-------RSRY 1951

Query: 764  ELVIRAA 770
            EL +RA+
Sbjct: 1952 ELTVRAS 1958



 Score =  202 bits (492), Expect = 1e-49
 Identities = 170/574 (29%), Positives = 275/574 (47%), Gaps = 43/574 (7%)

Query: 103 ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162
           A L+RE    YT++VKA ++ + V  R      + V ++D ND  P FS  +Y+VS+ E+
Sbjct: 106 AILNREVKDHYTLIVKALEKNTNVEARTK----VRVQVLDTNDLRPLFSPTSYSVSLPEN 161

Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222
            ++  +  IA++ ATDAD+G N    Y+     T M F+I   SG + L   LDY + + 
Sbjct: 162 TAIRTS--IARVSATDADIGTNGEFYYSF-KDRTDM-FAIHPTSGVIVLTGRLDYLETKL 217

Query: 223 YRLVIRAQDGG-----SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277
           Y + I A D G     S   S+  +L ++I   N+ AP         S  +  P  Y+IV
Sbjct: 218 YEMEILAADRGMKLYGSSGISSMAKLTVHIEQANECAPVITAVTLSPSELDRDP-AYAIV 276

Query: 278 RVQAYDADEGVNAEL-TYTMTDKDYTGNVDLPITIDPRSGW-VYTSGQLDRETQA-KYQL 334
            V   D D+G N ++ + ++   D         +      + V   G +D ++    Y L
Sbjct: 277 TVD--DCDQGANGDIASLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGDIDWDSHPFGYNL 334

Query: 335 LVTATDGGDPPR-SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393
            + A D G PP+ S+                 F    Y  E++E  PP TPVV + A  A
Sbjct: 335 TLQAKDKGTPPQFSSVKVIHVTSPQFKAGPVKFEKDVYRAEISEFAPPNTPVVMVKAIPA 394

Query: 394 DEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA 453
               R  ++ T G  + +FS+    G  LI++ +P+  +Q   + L V+ +D   R  + 
Sbjct: 395 YSHLRYVFKRTPG--KAKFSLNYNTG--LISILEPVKRQQAAHFELEVTTSD---RKAST 447

Query: 454 MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513
            V + +  AN+  P F    Y A+  E+ PIGTT++ +SA D D G N  +TYS+++   
Sbjct: 448 KVLVKVLGANSNPPEFTQTAYKAAFDENVPIGTTIMSLSAVDPDEGENGYVTYSIAN--- 504

Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSG-YLLTVTARDGGVPSLSDTTDV-EISV 571
                +H   F I+  TGA++T++ LD E M   Y L + A D G+P   +   +  I++
Sbjct: 505 ----LNH-VPFAIDHFTGAVSTSENLDYELMPRVYTLRIRASDWGLPYRREVEVLATITL 559

Query: 572 VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631
            ++NDN P+F++      I  D  VG  ++ V A DAD      + Y+++    E   F 
Sbjct: 560 NNLNDNTPLFEKINCEGTIPRDLGVGEQITTVSAIDADE--LQLVQYQIE-AGNELDLFS 616

Query: 632 IDPASGVIRTNKALD---RESVATHDLKAVAIDG 662
           ++P SGV+   ++L       V+ H L+  A DG
Sbjct: 617 LNPNSGVLSLKRSLMDGLGAKVSFHSLRITATDG 650



 Score =  139 bits (337), Expect = 9e-31
 Identities = 152/587 (25%), Positives = 250/587 (42%), Gaps = 39/587 (6%)

Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383
           L+RE +  Y L+V A +      + T                F P  Y V L E+    T
Sbjct: 108 LNREVKDHYTLIVKALEKNTNVEARTKVRVQVLDTNDLRPL-FSPTSYSVSLPENTAIRT 166

Query: 384 PVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443
            +  ++ATDAD      +  +  +    F+I   +G  +I +   LD+ + + Y + + A
Sbjct: 167 SIARVSATDADIGTNGEFYYSFKDRTDMFAIHPTSG--VIVLTGRLDYLETKLYEMEILA 224

Query: 444 TDSG-------GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496
            D G       G S  A + ++I  AN  APV      + S  +  P      +V+  D 
Sbjct: 225 ADRGMKLYGSSGISSMAKLTVHIEQANECAPVITAVTLSPSELDRDP---AYAIVTVDDC 281

Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS-GYLLTVTARD 555
           D G N  I  SLS    +        +     +   +     +D ++   GY LT+ A+D
Sbjct: 282 DQGANGDIA-SLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGDIDWDSHPFGYNLTLQAKD 340

Query: 556 GGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614
            G P   S    + ++          F++ +Y A I E A   T V  V A  A   L  
Sbjct: 341 KGTPPQFSSVKVIHVTSPQFKAGPVKFEKDVYRAEISEFAPPNTPVVMVKAIPAYSHL-- 398

Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674
           R  ++  P    +  F ++  +G+I   + + R+  A  +L+    D     ++ST ++ 
Sbjct: 399 RYVFKRTPG---KAKFSLNYNTGLISILEPVKRQQAAHFELEVTTSDR----KASTKVL- 450

Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734
           +K+   N +PP F          EN PIGTTI  + A DPDEG N  V YSI    +   
Sbjct: 451 VKVLGANSNPPEFTQTAYKAAFDENVPIGTTIMSLSAVDPDEGENGYVTYSI-ANLNHVP 509

Query: 735 FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVT----DVNDN 790
           F+++   G+    + T  +LDYE   + Y L IRA+   L     VE+L T    ++NDN
Sbjct: 510 FAIDHFTGA----VSTSENLDYELMPRVYTLRIRASDWGLPYRREVEVLATITLNNLNDN 565

Query: 791 APVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMT 850
            P+ +         +D         V A DAD    +QY+I +GN  +L  LN  +G ++
Sbjct: 566 TPLFEKINCEGTIPRDLGVGEQITTVSAIDADELQLVQYQIEAGNELDLFSLNPNSGVLS 625

Query: 851 LSPQLNTNV-PKLA--TMEVSVTDGVNEIKAMMQLSVRLITEEMLLN 894
           L   L   +  K++  ++ ++ TDG N     + +++ +     L+N
Sbjct: 626 LKRSLMDGLGAKVSFHSLRITATDGEN-FATPLYINITVAASHKLVN 671



 Score =  117 bits (282), Expect = 4e-24
 Identities = 136/565 (24%), Positives = 238/565 (42%), Gaps = 68/565 (12%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ VLD ND  P+F    Y  S+ E  +  T++  + ATD DIG N E  Y+ +  T   
Sbjct: 136 RVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGTNGEFYYSFKDRT--- 192

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV--S 127
                             D+F I   SG ++    LD  +   Y + + A D+   +  S
Sbjct: 193 ------------------DMFAIHPTSGVIVLTGRLDYLETKLYEMEILAADRGMKLYGS 234

Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVS-VDEDISVTDNPVIAKIKATDADVGANSA 186
             +SS A + V+I   N+  P  +  T + S +D D      P  A +   D D GAN  
Sbjct: 235 SGISSMAKLTVHIEQANECAPVITAVTLSPSELDRD------PAYAIVTVDDCDQGANGD 288

Query: 187 I-RYAIIGGNTQMQF-SIDSLSGD----VSLVKTLDYE-QVRSYRLVIRAQDGGSPSRSN 239
           I   +I+ G+   QF ++ S  G     V  +  +D++     Y L ++A+D G+P + +
Sbjct: 289 IASLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGDIDWDSHPFGYNLTLQAKDKGTPPQFS 348

Query: 240 TTQLL-INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
           + +++ +          +F   +++  +SE  P    +V V+A  A     + L Y    
Sbjct: 349 SVKVIHVTSPQFKAGPVKFEKDVYRAEISEFAPPNTPVVMVKAIPA----YSHLRYVF-- 402

Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358
           K   G      +++  +G +     + R+  A ++L VT +D     R A+         
Sbjct: 403 KRTPGKA--KFSLNYNTGLISILEPVKRQQAAHFELEVTTSD-----RKASTKVLVKVLG 455

Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQN 418
                  F    Y+    E+ P GT +++L+A D DE    +   +  N          +
Sbjct: 456 ANSNPPEFTQTAYKAAFDENVPIGTTIMSLSAVDPDEGENGYVTYSIANL-NHVPFAIDH 514

Query: 419 GRGLITVAQPLDFK-QERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPY 474
             G ++ ++ LD++   R Y L + A+D G    R    +  I + + N+  P+FE    
Sbjct: 515 FTGAVSTSENLDYELMPRVYTLRIRASDWGLPYRREVEVLATITLNNLNDNTPLFEKINC 574

Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
             ++  D  +G  +  VSA D+D     Q+      E  NE        F +NP +G ++
Sbjct: 575 EGTIPRDLGVGEQITTVSAIDAD---ELQLV-QYQIEAGNEL-----DLFSLNPNSGVLS 625

Query: 535 TNK-LLD--RETMSGYLLTVTARDG 556
             + L+D     +S + L +TA DG
Sbjct: 626 LKRSLMDGLGAKVSFHSLRITATDG 650



 Score =  109 bits (261), Expect = 1e-21
 Identities = 92/356 (25%), Positives = 164/356 (46%), Gaps = 23/356 (6%)

Query: 113 YTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIA 172
           Y + ++A D+ +P   + SS   IHV          +F +  Y   + E  +  + PV+ 
Sbjct: 332 YNLTLQAKDKGTP--PQFSSVKVIHVTSPQFKAGPVKFEKDVYRAEISE-FAPPNTPVVM 388

Query: 173 KIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232
            +KA    + A S +RY       + +FS++  +G +S+++ +  +Q   + L +   D 
Sbjct: 389 -VKA----IPAYSHLRYVFKRTPGKAKFSLNYNTGLISILEPVKRQQAAHFELEVTTSD- 442

Query: 233 GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292
               R  +T++L+ +   N N P F  + ++ +  ENVPIG +I+ + A D DEG N  +
Sbjct: 443 ----RKASTKVLVKVLGANSNPPEFTQTAYKAAFDENVPIGTTIMSLSAVDPDEGENGYV 498

Query: 293 TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDP-PRSATA 350
           TY++ + ++     +P  ID  +G V TS  LD E   + Y L + A+D G P  R    
Sbjct: 499 TYSIANLNH-----VPFAIDHFTGAVSTSENLDYELMPRVYTLRIRASDWGLPYRREVEV 553

Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG 410
                          F     E  +  D   G  + T++A DADE   + Y+I  GN   
Sbjct: 554 LATITLNNLNDNTPLFEKINCEGTIPRDLGVGEQITTVSAIDADELQLVQYQIEAGNELD 613

Query: 411 RFSITSQNGRGLITVAQPL-DFKQERRYVLTVSATDSGGRSDTAMVQINITDANNY 465
            FS+   +  G++++ + L D    +    ++  T + G +    + INIT A ++
Sbjct: 614 LFSLNPNS--GVLSLKRSLMDGLGAKVSFHSLRITATDGENFATPLYINITVAASH 667



 Score =  100 bits (240), Expect = 5e-19
 Identities = 95/357 (26%), Positives = 161/357 (45%), Gaps = 22/357 (6%)

Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
           +L+RE    Y L V A +    ++   T V + V+D ND  P+F    Y+ ++ E+  + 
Sbjct: 107 ILNREVKDHYTLIVKALEKNT-NVEARTKVRVQVLDTNDLRPLFSPTSYSVSLPENTAIR 165

Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
           TS+++V ATDAD+G NG  +Y    KDR +  F I P SGVI     LD      ++++ 
Sbjct: 166 TSIARVSATDADIGTNGEFYYSF--KDRTD-MFAIHPTSGVIVLTGRLDYLETKLYEMEI 222

Query: 658 VAIDGGTPPQSSTVI-----VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
           +A D G     S+ I     + + IE  N+  PV  +  L+    +  P       +   
Sbjct: 223 LAADRGMKLYGSSGISSMAKLTVHIEQANECAPVITAVTLSPSELDRDP---AYAIVTVD 279

Query: 713 DPDEGPNA-VVHYSIKGGDDSNSF-SLETRQGSDKAELVTMVDLDYESPRKKYELVIRA- 769
           D D+G N  +   SI  GD    F ++ +  GS + ++  + D+D++S    Y L ++A 
Sbjct: 280 DCDQGANGDIASLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGDIDWDSHPFGYNLTLQAK 339

Query: 770 --ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCF--PVGPFGRVPAYDADVTD 825
              +PP ++ V+V I VT     A  +K  + ++      F  P  P   V A  A    
Sbjct: 340 DKGTPPQFSSVKV-IHVTSPQFKAGPVKFEKDVYRAEISEFAPPNTPVVMVKAIPA--YS 396

Query: 826 KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQL 882
            L+Y            LN  TG +++   +         +EV+ +D     K ++++
Sbjct: 397 HLRYVFKRTPGKAKFSLNYNTGLISILEPVKRQQAAHFELEVTTSDRKASTKVLVKV 453



 Score = 75.8 bits (178), Expect = 2e-11
 Identities = 75/241 (31%), Positives = 111/241 (46%), Gaps = 34/241 (14%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + VL  N + P F    Y+A+  E    GTT+++L A D D G+N  V Y+I       L
Sbjct: 451 VKVLGANSNPPEFTQTAYKAAFDENVPIGTTIMSLSAVDPDEGENGYVTYSIA-----NL 505

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSDR 129
           N                  F ID  +GA+ T  +LD E + R YT+ ++A+D   P    
Sbjct: 506 NHVP---------------FAIDHFTGAVSTSENLDYELMPRVYTLRIRASDWGLPYRRE 550

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           +   ATI +N +  NDN P F +     ++  D+ V +   I  + A DAD      ++Y
Sbjct: 551 VEVLATITLNNL--NDNTPLFEKINCEGTIPRDLGVGEQ--ITTVSAIDAD--ELQLVQY 604

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLD---YEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            I  GN    FS++  SG +SL ++L      +V  + L I A DG     +  T L IN
Sbjct: 605 QIEAGNELDLFSLNPNSGVLSLKRSLMDGLGAKVSFHSLRITATDG----ENFATPLYIN 660

Query: 247 I 247
           I
Sbjct: 661 I 661



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 97/415 (23%), Positives = 146/415 (35%), Gaps = 58/415 (13%)

Query: 1310 CPEKRSRCSSAPCYNGAEC-SDLW-DTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFN 1367
            CP     C   PC  G+EC SD W + + C C  G  G+ C  S+       G+  + + 
Sbjct: 3789 CPPVHHGCEDDPCPEGSECVSDPWEEKHTCVCPSGRFGQ-CPGSSS--MTLTGNSYVKYR 3845

Query: 1368 PLLRPIQLPWLNALSIRTRQRDAFVM--------SIQLKSGLLHYSYN-GE---TMYLPM 1415
                  +L     + +RT    A VM         +++  G L Y ++ G     + +  
Sbjct: 3846 LTENENKLEMKLTMRLRTYSTHAVVMYARGTDYSILEIHHGRLQYKFDCGSGPGIVSVQS 3905

Query: 1416 ATLSDGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGL- 1474
              ++DG WH + ++  G    + +D  + T                 +  GG     G  
Sbjct: 3906 IQVNDGQWHAVALEVNGNYARLVLDQ-VHTASGTAPGTLKTLNLDNYVFFGGHIRQQGTR 3964

Query: 1475 --LASDVG-FFEGCIQDVRIGTAQSLLN-RPT----VRE--NVRDGC--QSRADCMLSIC 1522
               +  VG  F GC+  + +   +  LN +P     + E  +V  GC   +  DC  + C
Sbjct: 3965 HGRSPQVGNGFRGCMDSIYLNGQELPLNSKPRSYAHIEESVDVSPGCFLTATEDCASNPC 4024

Query: 1523 PPYSKCVTS-WDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGYSCACEP 1577
                 C  S      C C A  +G  C   V+ C   PC     CV D    G+ C C  
Sbjct: 4025 QNGGVCNPSPAGGYYCKCSALYIGTHCEISVNPCSSNPCLYGGTCVVDN--GGFVCQCRG 4082

Query: 1578 GYTLTTSGCIESGKEE-CPGGWWGGSACGPCACDVTRGYH-PHCNKENGKCHCKENHYKP 1635
             YT          K+E C  G     +     C    G+    C  +  +C         
Sbjct: 4083 LYTGQRCQLSPYCKDEPCKNGGTCFDSLDGAVCQCDSGFRGERCQSDIDEC--------- 4133

Query: 1636 EGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC-DACANAYAEVTPNSG 1689
             G     PC  + A  EN+     +  C+C     GR C DA  N Y     N G
Sbjct: 4134 SGN----PC-LHGALCENTH---GSYHCNCSHEYRGRHCEDAAPNQYVSTPWNIG 4180


>UniRef50_Q9VW71 Cluster: Putative fat-like cadherin-related tumor
            suppressor homolog precursor; n=3; Diptera|Rep: Putative
            fat-like cadherin-related tumor suppressor homolog
            precursor - Drosophila melanogaster (Fruit fly)
          Length = 4705

 Score =  443 bits (1092), Expect = e-122
 Identities = 355/1244 (28%), Positives = 584/1244 (46%), Gaps = 107/1244 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I+V D ND+ P F+   Y ASV E +    +++ + ATD D G N ++ Y +E   +DT 
Sbjct: 2864 IDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYYLE---SDTE 2920

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N              +Q++F ID  SG +    SLDRE  + Y   V A D   P  D  
Sbjct: 2921 N--------------IQNIFDIDIYSGWITLLTSLDREVQSEYNFKVIAADNGHPKHD-- 2964

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             +   + + I+D NDN P F      +SV E+       V+  +   D D+     + + 
Sbjct: 2965 -AKVPVTIKIVDYNDNAPVFKLPIEGLSVFEN--ALPGTVLINLLLIDPDI-EKQEMDFF 3020

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I+ G+ Q QF I   SG++ + K LD EQ+  Y L I A DG   +++N     I+++D+
Sbjct: 3021 IVSGDKQAQFQIGK-SGELFIAKPLDREQLMFYNLSIIATDGKFTAKANVE---IDVKDI 3076

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN P      +  S +E++ IG ++V V+A D D    ++L + ++ K   G  D   +
Sbjct: 3077 NDNTPYCLKPRYHISTNESISIGTTLVEVKAIDFD--FQSKLRFYLSGK---GADDF--S 3129

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            I   SG +  +  LDRET  KY+L+    DG D  +   +               F   Q
Sbjct: 3130 IGKESGILKVASALDRETTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIFSMAQ 3189

Query: 371  YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
            Y V + ED    T +  + A D D   + ++ Y + G N    F I+   G  +I + + 
Sbjct: 3190 YRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGEN-HDYFKISKSTG--IIRLHKS 3246

Query: 429  LDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
            LD +    + LTV A D G       A V +NI D N+  P F    Y+  + E+A  GT
Sbjct: 3247 LDRETISLFNLTVKAEDCGVPKLHSIATVAVNILDINDNPPEFSMRQYSCKILENATHGT 3306

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
             V  V AT  D+G+NA I Y + S   NE       +F ++  TG +  N  LD E    
Sbjct: 3307 EVCKVYATSIDIGVNADIHYFIMS--GNE-----QGKFKMDSTTGDLVLNATLDYEMSKF 3359

Query: 547  YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
            Y LT+ A DGG P LS+   V IS++D+NDN P F Q LY  N+ ED  VG+ +  V AT
Sbjct: 3360 YFLTIQAIDGGTPPLSNNAYVNISILDINDNSPTFLQNLYRINVNEDIFVGSKILDVKAT 3419

Query: 607  DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
            D D  +NG + Y ++  D   G F IDP +G I  ++ LDRE+++ + L+  A D G P 
Sbjct: 3420 DEDSDVNGLVTYNIERGDNI-GQFSIDPKNGTISVSRPLDRETISHYTLEIQACDQGDPQ 3478

Query: 667  QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH-YS 725
            + ++V ++I I D ND+ P+F S   +  + EN  +G      +  D DE PN   + + 
Sbjct: 3479 RCNSVPININILDTNDNAPIFSSSNYSVVLQENRLLGYVFLTFKISDADETPNTTPYTFD 3538

Query: 726  IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVT 785
            I+ G++   F LE + GS +    +  + + +        V    +PPL++D  V + + 
Sbjct: 3539 IRSGNEGGLFRLE-QDGSLRT--ASRFNHNLQDEFVIQVRVFDNGTPPLYSDAWVVVKII 3595

Query: 786  DVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSG-----NNANLI 840
            + +   P++   ++  N+++D F     G+V A D D  D+L + ++SG      ++ L 
Sbjct: 3596 EESQYPPIVTPLEVTINSFEDDFSGAFIGKVHASDQDKYDELNFSLVSGPDDMYQSSKLF 3655

Query: 841  LLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRL 900
             ++  TG +     L+  + KL    VSV+DG   + ++++++V L+T +ML  S+ +R 
Sbjct: 3656 NISNNTGKIYAISNLDIGLYKL---NVSVSDGKFHVFSIVKINVELVTNDMLKESVVIRF 3712

Query: 901  NDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEV 960
              ++A +FL      F+  +  I+ C ++++ + ++Q D          +  AR  D+++
Sbjct: 3713 RRISASEFLLSHRKTFMRSIRNIMRCRQKDVILITLQSDYQKASQHAVGNRRARSIDSDL 3772

Query: 961  GVA---------GDPSPHYSPTHLRERVYLHRTTL---ARLATVQVLP----FDDNICVH 1004
             V           D    ++   +R+ +   +  +     L    VLP     + N CVH
Sbjct: 3773 NVVFAVRKQQIIPDSDEFFTSDEIRQTLIDKKNEIENETNLVVEDVLPSTCQSNKNDCVH 3832

Query: 1005 EPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASC 1064
              C   ++ L +LK    + F +  S       PV   TC C  GF G +C+  +   S 
Sbjct: 3833 GEC---KQILQILKNNVTTTFTDVISFAAPSYIPVN--TCVCRPGFDGKHCKETVNACST 3887

Query: 1065 EVDGDGSICR-SGS----QCVARRE-GGILCQGCSIDAAYTTAVCEL-RARSFPVSSFLT 1117
            +      IC  SGS    QCV  +   G  C+  S   +  +    L  A SF   S+  
Sbjct: 3888 DPCSPQRICMPSGSALGYQCVCPKGFSGTYCERKSSKCSNESCDMGLFTAVSFGGKSYAH 3947

Query: 1118 FPGLKRRHRIHLK------LKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRGGGPG 1171
            +   K + +  L+      L+  T   +G LLY    + + D+  LE+++          
Sbjct: 3948 YKINKVKAKFTLENGFSYSLQIRTVQQTGTLLY---ASGKVDYNILEIING--------A 3996

Query: 1172 LRFSFSLGGGKSEITVEG-NVGDGSWHTVEIEYFNRTITMILDD 1214
            +++ F LG G+  I+V   N+ DG WH + +E    +  +++D+
Sbjct: 3997 VQYRFDLGSGEGVISVSSINISDGEWHQISLERSLNSAKVMVDN 4040



 Score =  355 bits (874), Expect = 8e-96
 Identities = 274/877 (31%), Positives = 414/877 (47%), Gaps = 48/877 (5%)

Query: 87   QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146
            QD F I   SG L+ + +LDRE+   + ++V A     PV     + A + +++ D+NDN
Sbjct: 2817 QDHFMISD-SGELILQQTLDREQQESHNLIVVAETSTVPV---FFAYADVLIDVRDENDN 2872

Query: 147  YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ--FSIDS 204
            YP+F    Y+ SV E+     +  + K+ ATDAD G N  IRY +      +Q  F ID 
Sbjct: 2873 YPKFDNTFYSASVAENSEKVIS--LVKVSATDADTGPNGDIRYYLESDTENIQNIFDIDI 2930

Query: 205  LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
             SG ++L+ +LD E    Y   + A D G P       + I I D NDNAP F   +   
Sbjct: 2931 YSGWITLLTSLDREVQSEYNFKVIAADNGHPKHDAKVPVTIKIVDYNDNAPVFKLPIEGL 2990

Query: 265  SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
            SV EN   G  ++ +   D D     E+ + +   D      +      +SG ++ +  L
Sbjct: 2991 SVFENALPGTVLINLLLIDPDIE-KQEMDFFIVSGDKQAQFQIG-----KSGELFIAKPL 3044

Query: 325  DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
            DRE    Y L + ATDG     +A A                +  +Y +   E    GT 
Sbjct: 3045 DREQLMFYNLSIIATDG---KFTAKANVEIDVKDINDNTPYCLKPRYHISTNESISIGTT 3101

Query: 385  VVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444
            +V + A D D  ++L + ++G      FSI  ++G  ++ VA  LD +   +Y L     
Sbjct: 3102 LVEVKAIDFDFQSKLRFYLSGKGADD-FSIGKESG--ILKVASALDRETTPKYKLVAHVQ 3158

Query: 445  DSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502
            D    +     +I IT  D N+  P+F  A Y  SV EDA + T +  V A D D G+N 
Sbjct: 3159 DGKDFTQECFSEIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNR 3218

Query: 503  QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
            QI YSL  E       +HD  F I+  TG I  +K LDRET+S + LTV A D GVP L 
Sbjct: 3219 QIKYSLMGE-------NHDY-FKISKSTGIIRLHKSLDRETISLFNLTVKAEDCGVPKLH 3270

Query: 563  DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP 622
                V ++++D+NDN P F  + Y+  I+E+A  GT V +V AT  D+G+N  IHY +  
Sbjct: 3271 SIATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYATSIDIGVNADIHYFI-M 3329

Query: 623  KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND 682
               E+G F +D  +G +  N  LD E    + L   AIDGGTPP S+   V+I I DIND
Sbjct: 3330 SGNEQGKFKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDGGTPPLSNNAYVNISILDIND 3389

Query: 683  SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
            + P F  +     ++E+  +G+ I +++A D D   N +V Y+I+ GD+   FS++ + G
Sbjct: 3390 NSPTFLQNLYRINVNEDIFVGSKILDVKATDEDSDVNGLVTYNIERGDNIGQFSIDPKNG 3449

Query: 743  SDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVM--KDF 797
            +    +     LD E+    Y L I+A     P   N V + I + D NDNAP+    ++
Sbjct: 3450 T----ISVSRPLDRET-ISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFSSSNY 3504

Query: 798  QIIF-NNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
             ++   N    +    F    A +   T    + I SGN   L  L E  GS+  + + N
Sbjct: 3505 SVVLQENRLLGYVFLTFKISDADETPNTTPYTFDIRSGNEGGLFRL-EQDGSLRTASRFN 3563

Query: 857  TNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGF 915
             N+     ++V V D G   + +   + V++I E      +T    ++T   F     G 
Sbjct: 3564 HNLQDEFVIQVRVFDNGTPPLYSDAWVVVKIIEESQYPPIVTPL--EVTINSFEDDFSGA 3621

Query: 916  FIDGLAAIIPCPKE--NIYIFSVQDDTDVTGNILNVS 950
            FI  + A      +  N  + S  DD   +  + N+S
Sbjct: 3622 FIGKVHASDQDKYDELNFSLVSGPDDMYQSSKLFNIS 3658



 Score =  321 bits (788), Expect = 2e-85
 Identities = 255/858 (29%), Positives = 410/858 (47%), Gaps = 70/858 (8%)

Query: 17   NDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAX 76
            N H P F     E S+ E    G TV  ++A D+D+G N ++ + I     D+       
Sbjct: 763  NVHRPEFVNFPQELSINESVQLGETVAWIEAKDRDLGYNGKLVFAISDGDYDS------- 815

Query: 77   XXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATI 136
                        VFRID   G L     LDRE+   Y + +   D  +P     S++  +
Sbjct: 816  ------------VFRIDPDRGELQIIGYLDRERQNEYVLNITVYDLGNPTK---STSKML 860

Query: 137  HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNT 196
             + I+D NDN P   +   T  + E   +    V+  + ATDAD G N+ + YA+     
Sbjct: 861  PITILDVNDNRPVIQKTLATFRLTESARI--GTVVHCLHATDADSGINAQVTYAL--SVE 916

Query: 197  QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256
               F++++ +G + L K LD E+  +Y L I A+DGGSP  S+   + + + DVNDNAP 
Sbjct: 917  CSDFTVNATTGCLRLNKPLDREKQDNYALHITAKDGGSPVLSSEALVYVLVDDVNDNAPV 976

Query: 257  FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316
            F    +   V E++P G  +  ++A D D G NAE+ +++  K+ T + +L   ID  +G
Sbjct: 977  FGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSL--KEETQDEEL-FRIDKHTG 1033

Query: 317  WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG----QYE 372
             + T G LD E +  + L+V+A DGGDP  S T+               F P      YE
Sbjct: 1034 AIRTQGYLDYENKQVHNLIVSAIDGGDP--SLTSDMSIVIMIIDVNENRFAPEFDDFVYE 1091

Query: 373  VELAEDEPPGTPVVTLTATDADE---DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
             ++ E++P GT V+ +TA D D    ++++ Y ITGG+  G F++   N +G IT    L
Sbjct: 1092 GKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFAV---NDQGSITSLSQL 1148

Query: 430  DFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
            D + +  Y LT+ A D      S+   V I + + N+  P+ +   Y  +V E +     
Sbjct: 1149 DAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVENVE 1208

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKLLDRETMSG 546
            ++ + A D D+     ITY++   +S   V +    F I+ +TG I TT + LDRE  + 
Sbjct: 1209 IITLKAFDPDIDPTQTITYNI---VSGNLVGY----FEIDSKTGVIKTTERKLDRENQAE 1261

Query: 547  YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
            ++L V   D G P LS T+ + +SV+D+NDN P F Q++Y   +   A V  S+ QV A 
Sbjct: 1262 HILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQVPSSATVNQSIFQVHAI 1321

Query: 607  DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
            D+D G NGRI Y +    + +  F ID   G I   K LD ++     +KA   D G P 
Sbjct: 1322 DSDSGENGRITYSI-KSGKGKNKFRIDSQRGHIHIAKPLDSDNEFEIHIKAE--DNGIPK 1378

Query: 667  QSSTVIVHIKIEDIN----DSPPVFESDCLTFY-ISENSPIGTTIGEIRAHDPDEGPNAV 721
            +S T  V+I +  +N    ++P +          ++EN   G  + +I A D D   N  
Sbjct: 1379 KSQTARVNIVVVPVNPNSQNAPLIVRKTSENVVDLTENDKPGFLVTQILAVDDD---NDQ 1435

Query: 722  VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781
            + Y+I  G+D N+F +    G D   ++    LDYE+ ++ Y L I            + 
Sbjct: 1436 LWYNISNGNDDNTFYI----GQDNGNILLSKYLDYET-QQSYNLTISVTDGTFTAFTNLL 1490

Query: 782  ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNAN--- 838
            + V D+NDN P         N  ++        ++ A D D   KL Y + +  + +   
Sbjct: 1491 VQVIDINDNPPQFAKDVYHVNISENIEEESVIMQLHATDRDEDKKLFYHLHATQDPSSLA 1550

Query: 839  LILLNETTGSMTLSPQLN 856
            L  ++  +G++ ++ +L+
Sbjct: 1551 LFRIDSISGNVIVTQRLD 1568



 Score =  308 bits (755), Expect = 2e-81
 Identities = 246/873 (28%), Positives = 410/873 (46%), Gaps = 69/873 (7%)

Query: 15   DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
            D ND++PVF +Q+Y   VRE    GT +  ++A D+DIG NAE++++++  T D      
Sbjct: 969  DVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSLKEETQD------ 1022

Query: 75   AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134
                        +++FRID  +GA+ T+  LD E    + ++V A D   P    L+S  
Sbjct: 1023 ------------EELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDP---SLTSDM 1067

Query: 135  TIHVNIIDDNDN--YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSAIRYAI 191
            +I + IID N+N   P+F +  Y   V E  +      +  + A D D V  NS I Y+I
Sbjct: 1068 SIVIMIIDVNENRFAPEFDDFVYEGKVKE--NKPKGTFVMNVTARDMDTVDLNSKITYSI 1125

Query: 192  IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251
             GG+    F+++   G ++ +  LD E    Y L + AQD      SN  ++ I + + N
Sbjct: 1126 TGGDGLGIFAVND-QGSITSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENEN 1184

Query: 252  DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311
            DN P     ++  +V+E       I+ ++A+D D      +TY +     +GN+     I
Sbjct: 1185 DNIPLTDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTITYNIV----SGNLVGYFEI 1240

Query: 312  DPRSGWVYTS-GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            D ++G + T+  +LDRE QA++ L V  +D G P  S+T+               F    
Sbjct: 1241 DSKTGVIKTTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRV 1300

Query: 371  YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
            Y+V++         +  + A D+D  E+ R+ Y I  G  + +F I SQ  RG I +A+P
Sbjct: 1301 YKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIKSGKGKNKFRIDSQ--RGHIHIAKP 1358

Query: 429  LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDAN---NYAP--VFENAPYTASVFED 481
            LD   +  + + + A D+G   +S TA V I +   N     AP  V + +     + E+
Sbjct: 1359 LD--SDNEFEIHIKAEDNGIPKKSQTARVNIVVVPVNPNSQNAPLIVRKTSENVVDLTEN 1416

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
               G  V  + A D D   N Q+ Y++S+        + D  F I    G I  +K LD 
Sbjct: 1417 DKPGFLVTQILAVDDD---NDQLWYNISN-------GNDDNTFYIGQDNGNILLSKYLDY 1466

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
            ET   Y LT++  DG   + +  T++ + V+D+NDN P F + +Y  NI E+    + + 
Sbjct: 1467 ETQQSYNLTISVTDG---TFTAFTNLLVQVIDINDNPPQFAKDVYHVNISENIEEESVIM 1523

Query: 602  QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
            Q+ ATD D       H            F ID  SG +   + LD E  A H L     D
Sbjct: 1524 QLHATDRDEDKKLFYHLHATQDPSSLALFRIDSISGNVIVTQRLDFEKTAQHILIVFVKD 1583

Query: 662  GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
             G P + +   + + + D ND  P F +  +   + E++ IG+ + E+RA D D G NA 
Sbjct: 1584 QGAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVPESAAIGSKLAEVRAIDRDSGHNAE 1643

Query: 722  VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDV 778
            + YSI  G+  + F ++   G     ++T+      +  ++Y L ++A    +PPL + +
Sbjct: 1644 IQYSIITGNVGSVFEIDPTFG-----IITLAGNLNINKIQEYMLQVKAVDLGNPPLSSQI 1698

Query: 779  RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNAN 838
             V I+VT   ++ P      I    +++  P+G F  V    A  +  + + I+SGN   
Sbjct: 1699 PVHIIVTMSENDPPKFPTNNIAIEIFEN-LPIGTF--VTQVTARSSSSIFFNIISGNINE 1755

Query: 839  LILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
               +N +TG + ++  ++    K+  + V  T+
Sbjct: 1756 SFRINPSTGVIVINGNIDYESIKVFNLTVKGTN 1788



 Score =  302 bits (742), Expect = 7e-80
 Identities = 269/931 (28%), Positives = 428/931 (45%), Gaps = 73/931 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I +LD ND+ PV +       + E A  GT V  L ATD D G NA+V Y + +  +D  
Sbjct: 862  ITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHATDADSGINAQVTYALSVECSD-- 919

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F ++  +G L     LDREK   Y + + A D  SPV   L
Sbjct: 920  -------------------FTVNATTGCLRLNKPLDREKQDNYALHITAKDGGSPV---L 957

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            SS A ++V + D NDN P F  + Y   V ED+      V+A I+A D D+G N+ I+++
Sbjct: 958  SSEALVYVLVDDVNDNAPVFGVQEYIFKVREDL--PRGTVLAVIEAVDEDIGPNAEIQFS 1015

Query: 191  IIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
             +   TQ +  F ID  +G +     LDYE  + + L++ A DGG PS ++   ++I I 
Sbjct: 1016 -LKEETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMII 1074

Query: 249  DVNDN--APRFYTSLFQESVSENVPIGYSIVRVQAYDADE-GVNAELTYTMTDKDYTGNV 305
            DVN+N  AP F   +++  V EN P G  ++ V A D D   +N+++TY++T  D  G  
Sbjct: 1075 DVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLG-- 1132

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
               I      G + +  QLD ET+  Y L + A D    P S                  
Sbjct: 1133 ---IFAVNDQGSITSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPL 1189

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLI 423
                 Y V + E       ++TL A D D D    + Y I  GN  G F I S+ G  + 
Sbjct: 1190 TDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTG-VIK 1248

Query: 424  TVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFED 481
            T  + LD + +  ++L V+ +D+G    S T+ + +++ D N+ +P F+   Y   V   
Sbjct: 1249 TTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQVPSS 1308

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
            A +  ++  V A DSD G N +ITYS+ S            +F I+ Q G I   K LD 
Sbjct: 1309 ATVNQSIFQVHAIDSDSGENGRITYSIKS-------GKGKNKFRIDSQRGHIHIAKPLDS 1361

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP-----VFKQQLYTANIMEDALV 596
            +  + + + + A D G+P  S T  V I VV VN N       V K      ++ E+   
Sbjct: 1362 D--NEFEIHIKAEDNGIPKKSQTARVNIVVVPVNPNSQNAPLIVRKTSENVVDLTENDKP 1419

Query: 597  GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
            G  V+Q+ A D D   N ++ Y +     ++ +F I   +G I  +K LD E+  +++L 
Sbjct: 1420 GFLVTQILAVDDD---NDQLWYNIS-NGNDDNTFYIGQDNGNILLSKYLDYETQQSYNL- 1474

Query: 657  AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
             +++  GT    + ++V  ++ DIND+PP F  D     ISEN    + I ++ A D DE
Sbjct: 1475 TISVTDGTFTAFTNLLV--QVIDINDNPPQFAKDVYHVNISENIEEESVIMQLHATDRDE 1532

Query: 717  GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI--RAASPPL 774
              +  + Y +    D +S +L  R  S    ++    LD+E   +   +V      +P  
Sbjct: 1533 --DKKLFYHLHATQDPSSLAL-FRIDSISGNVIVTQRLDFEKTAQHILIVFVKDQGAPGK 1589

Query: 775  WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADV--TDKLQYRI 831
             N  ++ + V D ND+ P     +II +   +   +G     V A D D     ++QY I
Sbjct: 1590 RNYAKIIVNVHDHNDHHPEF-TAKIIQSKVPESAAIGSKLAEVRAIDRDSGHNAEIQYSI 1648

Query: 832  LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEM 891
            ++GN  ++  ++ T G +TL+  LN N  +   ++V   D +       Q+ V +I    
Sbjct: 1649 ITGNVGSVFEIDPTFGIITLAGNLNINKIQEYMLQVKAVD-LGNPPLSSQIPVHIIVTMS 1707

Query: 892  LLNSITVRLNDMTAEQFLSPLLGFFIDGLAA 922
              +      N++  E F +  +G F+  + A
Sbjct: 1708 ENDPPKFPTNNIAIEIFENLPIGTFVTQVTA 1738



 Score =  299 bits (735), Expect = 5e-79
 Identities = 229/759 (30%), Positives = 368/759 (48%), Gaps = 42/759 (5%)

Query: 144  NDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSID 203
            N + P+F      +S++E + + +   +A I+A D D+G N  + +AI  G+    F ID
Sbjct: 763  NVHRPEFVNFPQELSINESVQLGET--VAWIEAKDRDLGYNGKLVFAISDGDYDSVFRID 820

Query: 204  SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263
               G++ ++  LD E+   Y L I   D G+P++S +  L I I DVNDN P    +L  
Sbjct: 821  PDRGELQIIGYLDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLAT 880

Query: 264  ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323
              ++E+  IG  +  + A DAD G+NA++TY ++ +          T++  +G +  +  
Sbjct: 881  FRLTESARIGTVVHCLHATDADSGINAQVTYALSVE------CSDFTVNATTGCLRLNKP 934

Query: 324  LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383
            LDRE Q  Y L +TA DGG P  S+ A               F   +Y  ++ ED P GT
Sbjct: 935  LDREKQDNYALHITAKDGGSPVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGT 994

Query: 384  PVVTLTATDADEDNRLHYEIT-GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
             +  + A D D       + +    T+           G I     LD++ ++ + L VS
Sbjct: 995  VLAVIEAVDEDIGPNAEIQFSLKEETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVS 1054

Query: 443  ATDSGGRSDTAMVQINI----TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD- 497
            A D G  S T+ + I I     + N +AP F++  Y   V E+ P GT V+ V+A D D 
Sbjct: 1055 AIDGGDPSLTSDMSIVIMIIDVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDT 1114

Query: 498  VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG 557
            V +N++ITYS++        A +DQ        G+IT+   LD ET + Y LT+ A+D  
Sbjct: 1115 VDLNSKITYSITGGDGLGIFAVNDQ--------GSITSLSQLDAETKNFYWLTLCAQDCA 1166

Query: 558  VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617
            +  LS+  +V I V + NDN P+  + +Y  N+ E ++    +  + A D D+     I 
Sbjct: 1167 IVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTIT 1226

Query: 618  YELDPKDREEGSFVIDPASGVIR-TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676
            Y +       G F ID  +GVI+ T + LDRE+ A H L+    D G+P  SST  + + 
Sbjct: 1227 YNI-VSGNLVGYFEIDSKTGVIKTTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVS 1285

Query: 677  IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736
            + DIND+ P F+       +  ++ +  +I ++ A D D G N  + YSIK G   N F 
Sbjct: 1286 VLDINDNSPEFDQRVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIKSGKGKNKFR 1345

Query: 737  LETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVN---DN 790
            +++++G     +   +D D E     +E+ I+A     P      RV I+V  VN    N
Sbjct: 1346 IDSQRG--HIHIAKPLDSDNE-----FEIHIKAEDNGIPKKSQTARVNIVVVPVNPNSQN 1398

Query: 791  AP--VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGS 848
            AP  V K  + + +  ++  P     ++ A D D  D+L Y I +GN+ N   + +  G+
Sbjct: 1399 APLIVRKTSENVVDLTENDKPGFLVTQILAVDDD-NDQLWYNISNGNDDNTFYIGQDNGN 1457

Query: 849  MTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887
            + LS  L+    +   + +SVTDG     A   L V++I
Sbjct: 1458 ILLSKYLDYETQQSYNLTISVTDGT--FTAFTNLLVQVI 1494



 Score =  281 bits (688), Expect = 3e-73
 Identities = 257/904 (28%), Positives = 408/904 (45%), Gaps = 81/904 (8%)

Query: 6    CIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELV 65
            C+   I V + ND+ P+ +   Y  +V E +     ++TLKA D DI     + Y I  V
Sbjct: 1173 CVEVYIQVENENDNIPLTDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTITYNI--V 1230

Query: 66   TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLVKATDQAS 124
            + + +                   F ID ++G +  T   LDRE  A + + V  +D  S
Sbjct: 1231 SGNLVG-----------------YFEIDSKTGVIKTTERKLDRENQAEHILEVAISDNGS 1273

Query: 125  PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184
            PV   LSST+ I V+++D NDN P+F ++ Y V V    S T N  I ++ A D+D G N
Sbjct: 1274 PV---LSSTSRIVVSVLDINDNSPEFDQRVYKVQVPS--SATVNQSIFQVHAIDSDSGEN 1328

Query: 185  SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
              I Y+I  G  + +F IDS  G + + K LD +    + + I+A+D G P +S T ++ 
Sbjct: 1329 GRITYSIKSGKGKNKFRIDSQRGHIHIAKPLDSD--NEFEIHIKAEDNGIPKKSQTARVN 1386

Query: 245  INIRDVN---DNAPRFY--TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
            I +  VN    NAP     TS     ++EN   G+ + ++ A D D   N +L Y +++ 
Sbjct: 1387 IVVVPVNPNSQNAPLIVRKTSENVVDLTENDKPGFLVTQILAVDDD---NDQLWYNISN- 1442

Query: 300  DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
               GN D    I   +G +  S  LD ETQ  Y L ++ TDG     +A           
Sbjct: 1443 ---GNDDNTFYIGQDNGNILLSKYLDYETQQSYNLTISVTDG---TFTAFTNLLVQVIDI 1496

Query: 360  XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEI---TGGNTRGRFSITS 416
                  F    Y V ++E+    + ++ L ATD DED +L Y +      ++   F I S
Sbjct: 1497 NDNPPQFAKDVYHVNISENIEEESVIMQLHATDRDEDKKLFYHLHATQDPSSLALFRIDS 1556

Query: 417  QNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPY 474
             +G  ++T  Q LDF++  +++L V   D G  G+ + A + +N+ D N++ P F     
Sbjct: 1557 ISGNVIVT--QRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTAKII 1614

Query: 475  TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
             + V E A IG+ +  V A D D G NA+I YS+          +    F I+P  G IT
Sbjct: 1615 QSKVPESAAIGSKLAEVRAIDRDSGHNAEIQYSI-------ITGNVGSVFEIDPTFGIIT 1667

Query: 535  TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
                L+   +  Y+L V A D G P LS    V I V    ++ P F        I E+ 
Sbjct: 1668 LAGNLNINKIQEYMLQVKAVDLGNPPLSSQIPVHIIVTMSENDPPKFPTNNIAIEIFENL 1727

Query: 595  LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654
             +GT V+QV A       +  I + +   +  E SF I+P++GVI  N  +D ES+   +
Sbjct: 1728 PIGTFVTQVTARS-----SSSIFFNIISGNINE-SFRINPSTGVIVINGNIDYESIKVFN 1781

Query: 655  LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI----- 709
            L     +         +I+HI   D ND+ P F  +     + E++ IG+ + ++     
Sbjct: 1782 LTVKGTNMAAESSCQNIIIHIL--DANDNIPYFVQNEYVGALPESAAIGSYVLKVHDSSK 1839

Query: 710  -----RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764
                 +  D D G N +V Y I      N F +++  G+   EL+  +D +  +      
Sbjct: 1840 DHLTLQVKDADVGVNGMVEYHIVDDLAKNFFKIDSTTGA--IELLRQLDYETNAGYTFDV 1897

Query: 765  LVIRAASPPLWN--DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD 822
             V     P L +     V I V +VND  PV  + ++    +   F      +V A DAD
Sbjct: 1898 TVSDMGKPKLHSTTTAHVTIRVINVNDCPPVFNERELNVTLFLPTFENVFVRQVSAKDAD 1957

Query: 823  VTDKLQYRILSGNNANLILLNETTGSMTLS--PQLNTNVPKLATMEVSVTDGVNEIKAMM 880
              D L++ I+ GN      + + TG +T      LN    +   + V  +DG+     ++
Sbjct: 1958 -NDTLRFDIVDGNTNECFQIEKYTGIITTRNFEILNNENDRDYALHVRASDGIFSAILIV 2016

Query: 881  QLSV 884
            ++ V
Sbjct: 2017 KIKV 2020



 Score =  262 bits (641), Expect = 1e-67
 Identities = 235/830 (28%), Positives = 372/830 (44%), Gaps = 67/830 (8%)

Query: 88   DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
            + F I   +G +L    LD E    Y + +  TD         ++   + V +ID NDN 
Sbjct: 1447 NTFYIGQDNGNILLSKYLDYETQQSYNLTISVTDGT------FTAFTNLLVQVIDINDNP 1500

Query: 148  PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR-YAIIGGNTQMQFSIDSLS 206
            PQF++  Y V++ E+I   +  VI ++ ATD D         +A    ++   F IDS+S
Sbjct: 1501 PQFAKDVYHVNISENIE--EESVIMQLHATDRDEDKKLFYHLHATQDPSSLALFRIDSIS 1558

Query: 207  GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266
            G+V + + LD+E+   + L++  +D G+P + N  ++++N+ D ND+ P F   + Q  V
Sbjct: 1559 GNVIVTQRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKV 1618

Query: 267  SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326
             E+  IG  +  V+A D D G NAE+ Y++     TGNV     IDP  G +  +G L+ 
Sbjct: 1619 PESAAIGSKLAEVRAIDRDSGHNAEIQYSI----ITGNVGSVFEIDPTFGIITLAGNLNI 1674

Query: 327  ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386
                +Y L V A D G+PP S+                 F      +E+ E+ P GT V 
Sbjct: 1675 NKIQEYMLQVKAVDLGNPPLSSQIPVHIIVTMSENDPPKFPTNNIAIEIFENLPIGTFVT 1734

Query: 387  TLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446
             +TA  +   + + + I  GN    F I      G+I +   +D++  + + LTV  T+ 
Sbjct: 1735 QVTARSS---SSIFFNIISGNINESFRINPST--GVIVINGNIDYESIKVFNLTVKGTNM 1789

Query: 447  GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV----------SATDS 496
               S    + I+I DAN+  P F    Y  ++ E A IG+ VL V             D+
Sbjct: 1790 AAESSCQNIIIHILDANDNIPYFVQNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVKDA 1849

Query: 497  DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556
            DVG+N  + Y +  +++          F I+  TGAI   + LD ET +GY   VT  D 
Sbjct: 1850 DVGVNGMVEYHIVDDLAKNF-------FKIDSTTGAIELLRQLDYETNAGYTFDVTVSDM 1902

Query: 557  GVPSLSDTT--DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614
            G P L  TT   V I V++VND  PVF ++     +         V QV A DAD   N 
Sbjct: 1903 GKPKLHSTTTAHVTIRVINVNDCPPVFNERELNVTLFLPTFENVFVRQVSAKDAD---ND 1959

Query: 615  RIHYELDPKDREEGSFVIDPASGVIRTN--KALDRESVATHDLKAVAIDGGTPPQSSTVI 672
             + +++   +  E  F I+  +G+I T   + L+ E+   + L   A DG     S+ +I
Sbjct: 1960 TLRFDIVDGNTNE-CFQIEKYTGIITTRNFEILNNENDRDYALHVRASDG---IFSAILI 2015

Query: 673  VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732
            V IK+    DS   F+ +   F   EN+    TIG +         N  V Y I   + +
Sbjct: 2016 VKIKVLSAIDSNFAFQRESYRFSAFENNTKVATIGLVNVIGNTLDEN--VEYRIL--NPT 2071

Query: 733  NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVR-----VEILV 784
              F +    G+ K    T V  D E  +  Y L + A S     + ++VR     ++I V
Sbjct: 2072 QLFDIGISSGALK---TTGVIFDRE-VKDLYRLFVEAKSMLYDGMNSNVRRAVTSIDISV 2127

Query: 785  TDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADVTDKLQYRI-LSGNNANLILL 842
             DVNDN P+  +         D  P G    +V A D D  +  + R  L   N  L  L
Sbjct: 2128 LDVNDNCPLFVNMPYYATVSID-DPKGTIIMQVKAIDLDSAENGEVRYELKKGNGELFKL 2186

Query: 843  NETTGSMTLSPQLNTNVPKLATMEVSVTDG-VNEIKAMMQLSVRLITEEM 891
            +  +G +++   +  +  +   + V+  DG +    +   L V++I   M
Sbjct: 2187 DRKSGELSIKQHVEGH-NRNYELTVAAYDGAITPCSSEAPLQVKVIDRSM 2235



 Score =  258 bits (633), Expect = 1e-66
 Identities = 248/889 (27%), Positives = 384/889 (43%), Gaps = 81/889 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            ++++D ND  P  E   Y  ++ E AS GT +L + ATD D G NA++ Y IE +     
Sbjct: 2326 VSIMDVNDCYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQN- 2384

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP----- 125
            N E               +F ID   G L  +  LD E++  + ++V   D  SP     
Sbjct: 2385 NSE---------------LFYIDVTDGNLYLKTPLDYEQIKYHHIVVNVKDHGSPSLSSR 2429

Query: 126  --------VSDRLSSTATIHVNII---DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKI 174
                    +  R  S   I+ +II   D NDN P F E +Y   V   ++      +A  
Sbjct: 2430 SNVFITGRILCRFISYKLIYDSIIPVKDLNDNAPCFVEPSYFTKV--SVAAVRGQFVALP 2487

Query: 175  KATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS 234
            KA D D+    ++ Y I+ GN    +SID L+G +SL   L++    S  L I   DG  
Sbjct: 2488 KAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQNMLNFTDKSSTVLNISVSDG-- 2545

Query: 235  PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294
               +   +L I++   N  +P F  S ++  V EN+  G++I+ V+A D D G  A L Y
Sbjct: 2546 -VHTAYARLKISLLPENVYSPLFDQSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYY 2604

Query: 295  TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354
             +  ++    +     ID  +G + +    DRE + +Y +L+  +DGG   +   A+   
Sbjct: 2605 EIVSEE----MKKIFLIDQTTGVITSKVTFDREKKDEYVVLLKVSDGGG--KFGFASLKV 2658

Query: 355  XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEIT-GGNTRGR 411
                       F+  +Y++ ++        ++T+ A D D  ++  +H++I    N +  
Sbjct: 2659 IVVDVNDNVPYFLLKEYKMVVSTTVEANQTILTVKAKDDDIVDNGSVHFQIVQKSNDKAV 2718

Query: 412  FSITSQNGR-GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINI----TDANNYA 466
              +   N + G I      +      Y   V A+D G     + V ++I    TDAN   
Sbjct: 2719 KDVIEINEKTGDIVFKSKAESYGVNSYQFFVRASDRGEPQFHSEVPVSIEIIETDAN--I 2776

Query: 467  PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
            P FE +     + E  P GT +  +      +G N    +S+++          DQ   +
Sbjct: 2777 PTFEKSSVLLKIIESTPPGTVLTKLHM----IG-NYTFKFSIAA----------DQDHFM 2821

Query: 527  NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586
               +G +   + LDRE    + L V A    VP      DV I V D NDN P F    Y
Sbjct: 2822 ISDSGELILQQTLDREQQESHNLIVVAETSTVPVFFAYADVLIDVRDENDNYPKFDNTFY 2881

Query: 587  TANIMEDALVGTSVSQVGATDADVGLNGRIHYELD-PKDREEGSFVIDPASGVIRTNKAL 645
            +A++ E++    S+ +V ATDAD G NG I Y L+   +  +  F ID  SG I    +L
Sbjct: 2882 SASVAENSEKVISLVKVSATDADTGPNGDIRYYLESDTENIQNIFDIDIYSGWITLLTSL 2941

Query: 646  DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
            DRE  + ++ K +A D G P   + V V IKI D ND+ PVF+       + EN+  GT 
Sbjct: 2942 DREVQSEYNFKVIAADNGHPKHDAKVPVTIKIVDYNDNAPVFKLPIEGLSVFENALPGTV 3001

Query: 706  IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765
            +  +   DPD      + + I  GD    F +         EL     LD E     Y L
Sbjct: 3002 LINLLLIDPDI-EKQEMDFFIVSGDKQAQFQI-----GKSGELFIAKPLDREQ-LMFYNL 3054

Query: 766  VIRAASPPLWNDVRVEILVTDVNDNAP-VMKDFQIIFNNYKDCFPVG-PFGRVPAYDADV 823
             I A          VEI V D+NDN P  +K    I  N  +   +G     V A D D 
Sbjct: 3055 SIIATDGKFTAKANVEIDVKDINDNTPYCLKPRYHISTN--ESISIGTTLVEVKAIDFDF 3112

Query: 824  TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
              KL++  LSG  A+   + + +G + ++  L+        +   V DG
Sbjct: 3113 QSKLRF-YLSGKGADDFSIGKESGILKVASALDRETTPKYKLVAHVQDG 3160



 Score =  249 bits (610), Expect = 7e-64
 Identities = 236/879 (26%), Positives = 381/879 (43%), Gaps = 79/879 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I++L  N +SP+F+   YEA V E    G  ++T+KA+D D G  A + Y  E+V+ + 
Sbjct: 2554 KISLLPENVYSPLFDQSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYY--EIVSEE- 2610

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                            ++ +F ID  +G + ++ + DREK   Y VL+K +D        
Sbjct: 2611 ----------------MKKIFLIDQTTGVITSKVTFDREKKDEYVVLLKVSDGGGKF--- 2651

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
                A++ V ++D NDN P F  K Y + V    +V  N  I  +KA D D+  N ++ +
Sbjct: 2652 --GFASLKVIVVDVNDNVPYFLLKEYKMVV--STTVEANQTILTVKAKDDDIVDNGSVHF 2707

Query: 190  AIIGGNTQMQ----FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
             I+  +          I+  +GD+      +   V SY+  +RA D G P   +   + I
Sbjct: 2708 QIVQKSNDKAVKDVIEINEKTGDIVFKSKAESYGVNSYQFFVRASDRGEPQFHSEVPVSI 2767

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM-TDKDYTGN 304
             I + + N P F  S     + E+ P G  + ++         N    +++  D+D+   
Sbjct: 2768 EIIETDANIPTFEKSSVLLKIIESTPPGTVLTKLHMIG-----NYTFKFSIAADQDHFMI 2822

Query: 305  VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
             D        SG +     LDRE Q  + L+V A     P   A A              
Sbjct: 2823 SD--------SGELILQQTLDREQQESHNLIVVAETSTVPVFFAYADVLIDVRDENDNYP 2874

Query: 365  XFMPGQYEVELAEDEPPGTPVVTLTATDADE----DNRLHYEITGGNTRGRFSITSQNGR 420
             F    Y   +AE+      +V ++ATDAD     D R + E    N +  F I   +  
Sbjct: 2875 KFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYYLESDTENIQNIFDIDIYS-- 2932

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASV 478
            G IT+   LD + +  Y   V A D+G     A   V I I D N+ APVF+      SV
Sbjct: 2933 GWITLLTSLDREVQSEYNFKVIAADNGHPKHDAKVPVTIKIVDYNDNAPVFKLPIEGLSV 2992

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
            FE+A  GT ++ +   D D+       + +S +           QF I  ++G +   K 
Sbjct: 2993 FENALPGTVLINLLLIDPDIEKQEMDFFIVSGD--------KQAQFQIG-KSGELFIAKP 3043

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            LDRE +  Y L++ A DG     +   +VEI V D+NDN P   +  Y  +  E   +GT
Sbjct: 3044 LDREQLMFYNLSIIATDG---KFTAKANVEIDVKDINDNTPYCLKPRYHISTNESISIGT 3100

Query: 599  SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
            ++ +V A D D     ++ + L  K  ++  F I   SG+++   ALDRE+   + L A 
Sbjct: 3101 TLVEVKAIDFD--FQSKLRFYLSGKGADD--FSIGKESGILKVASALDRETTPKYKLVAH 3156

Query: 659  AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
              DG    Q     + I + DIND+ P+F        + E++ + T I ++ A D D G 
Sbjct: 3157 VQDGKDFTQECFSEIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGV 3216

Query: 719  NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLW 775
            N  + YS+  G++ + F +    G  +        LD E+    + L ++A     P L 
Sbjct: 3217 NRQIKYSLM-GENHDYFKISKSTGIIRLH----KSLDRET-ISLFNLTVKAEDCGVPKLH 3270

Query: 776  NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA--YDADVTDKLQYRILS 833
            +   V + + D+NDN P     Q      ++        +V A   D  V   + Y I+S
Sbjct: 3271 SIATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYATSIDIGVNADIHYFIMS 3330

Query: 834  GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            GN      ++ TTG + L+  L+  + K   + +   DG
Sbjct: 3331 GNEQGKFKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDG 3369



 Score =  247 bits (605), Expect = 3e-63
 Identities = 229/841 (27%), Positives = 371/841 (44%), Gaps = 73/841 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            ++VLD ND+SP F+ + Y+  V   A+   ++  + A D D G+N  + Y+I+       
Sbjct: 1284 VSVLDINDNSPEFDQRVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIK------- 1336

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                            ++ FRID + G +     LD +    + + +KA D   P   + 
Sbjct: 1337 ------------SGKGKNKFRIDSQRGHIHIAKPLDSDN--EFEIHIKAEDNGIPKKSQT 1382

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP--VIAKIKATDADVGANSAIR 188
            +    + V +  ++ N P    KT    VD  ++  D P  ++ +I A D D   N  + 
Sbjct: 1383 ARVNIVVVPVNPNSQNAPLIVRKTSENVVD--LTENDKPGFLVTQILAVDDD---NDQLW 1437

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            Y I  GN    F I   +G++ L K LDYE  +SY L I   DG   + +  T LL+ + 
Sbjct: 1438 YNISNGNDDNTFYIGQDNGNILLSKYLDYETQQSYNLTISVTDG---TFTAFTNLLVQVI 1494

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            D+NDN P+F   ++  ++SEN+     I+++ A D DE  + +L Y +       ++ L 
Sbjct: 1495 DINDNPPQFAKDVYHVNISENIEEESVIMQLHATDRDE--DKKLFYHLHATQDPSSLAL- 1551

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
              ID  SG V  + +LD E  A++ L+V   D G P +   A               F  
Sbjct: 1552 FRIDSISGNVIVTQRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTA 1611

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVA 426
               + ++ E    G+ +  + A D D  +   + Y I  GN    F I      G+IT+A
Sbjct: 1612 KIIQSKVPESAAIGSKLAEVRAIDRDSGHNAEIQYSIITGNVGSVFEIDPT--FGIITLA 1669

Query: 427  QPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
              L+  + + Y+L V A D G    S    V I +T + N  P F        +FE+ PI
Sbjct: 1670 GNLNINKIQEYMLQVKAVDLGNPPLSSQIPVHIIVTMSENDPPKFPTNNIAIEIFENLPI 1729

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            GT V  V+A  S     + I +++ S   NE+       F INP TG I  N  +D E++
Sbjct: 1730 GTFVTQVTARSS-----SSIFFNIISGNINES-------FRINPSTGVIVINGNIDYESI 1777

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV- 603
              + LTV  +   + + S   ++ I ++D NDN P F Q  Y   + E A +G+ V +V 
Sbjct: 1778 KVFNLTV--KGTNMAAESSCQNIIIHILDANDNIPYFVQNEYVGALPESAAIGSYVLKVH 1835

Query: 604  ---------GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654
                        DADVG+NG + Y +   D  +  F ID  +G I   + LD E+ A + 
Sbjct: 1836 DSSKDHLTLQVKDADVGVNGMVEYHI-VDDLAKNFFKIDSTTGAIELLRQLDYETNAGYT 1894

Query: 655  LKAVAIDGGTPPQSSTVIVH--IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
                  D G P   ST   H  I++ ++ND PPVF    L   +   +     + ++ A 
Sbjct: 1895 FDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPPVFNERELNVTLFLPTFENVFVRQVSAK 1954

Query: 713  DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP 772
            D D   N  + + I  G+ +  F +E   G        +  L+ E+ R  Y L +RA+  
Sbjct: 1955 DAD---NDTLRFDIVDGNTNECFQIEKYTGIITTRNFEI--LNNENDR-DYALHVRASDG 2008

Query: 773  PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRIL 832
                 + V+I V    D+    +     F+ +++   V   G V      + + ++YRIL
Sbjct: 2009 IFSAILIVKIKVLSAIDSNFAFQRESYRFSAFENNTKVATIGLVNVIGNTLDENVEYRIL 2068

Query: 833  S 833
            +
Sbjct: 2069 N 2069



 Score =  241 bits (590), Expect = 2e-61
 Identities = 239/885 (27%), Positives = 384/885 (43%), Gaps = 65/885 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND++P F    Y   V   A  G  V   KA D+DI     +EY I  V  + L
Sbjct: 2453 IPVKDLNDNAPCFVEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKI--VYGNEL 2510

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               + ID  +G +  +  L+    +   + +  +D       RL
Sbjct: 2511 Q-----------------TYSIDKLTGVISLQNMLNFTDKSSTVLNISVSDGVHTAYARL 2553

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
                   ++++ +N   P F + TY   V E++    N  I  +KA+D D G  + + Y 
Sbjct: 2554 K------ISLLPENVYSPLFDQSTYEAQVPENLLHGHN--IITVKASDGDFGTYANLYYE 2605

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I+    +  F ID  +G ++   T D E+   Y ++++  DGG   +     L + + DV
Sbjct: 2606 IVSEEMKKIFLIDQTTGVITSKVTFDREKKDEYVVLLKVSDGG--GKFGFASLKVIVVDV 2663

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN P F    ++  VS  V    +I+ V+A D D   N  + + +  K     V   I 
Sbjct: 2664 NDNVPYFLLKEYKMVVSTTVEANQTILTVKAKDDDIVDNGSVHFQIVQKSNDKAVKDVIE 2723

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            I+ ++G +    + +      YQ  V A+D G+P   +                 F    
Sbjct: 2724 INEKTGDIVFKSKAESYGVNSYQFFVRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSS 2783

Query: 371  YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
              +++ E  PPGT    LT      +    + I     +  F I+     G + + Q LD
Sbjct: 2784 VLLKIIESTPPGT---VLTKLHMIGNYTFKFSIAA--DQDHFMISDS---GELILQQTLD 2835

Query: 431  FKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
             +Q+  + L V A  S      A   V I++ D N+  P F+N  Y+ASV E++    ++
Sbjct: 2836 REQQESHNLIVVAETSTVPVFFAYADVLIDVRDENDNYPKFDNTFYSASVAENSEKVISL 2895

Query: 489  LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
            + VSATD+D G N  I Y L S+  N         F I+  +G IT    LDRE  S Y 
Sbjct: 2896 VKVSATDADTGPNGDIRYYLESDTEN-----IQNIFDIDIYSGWITLLTSLDREVQSEYN 2950

Query: 549  LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
              V A D G P       V I +VD NDN PVFK  +   ++ E+AL GT +  +   D 
Sbjct: 2951 FKVIAADNGHPKHDAKVPVTIKIVDYNDNAPVFKLPIEGLSVFENALPGTVLINLLLIDP 3010

Query: 609  DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
            D+     + + +   D+ +  F I   SG +   K LDRE +  ++L  +A DG    ++
Sbjct: 3011 DIE-KQEMDFFIVSGDK-QAQFQIG-KSGELFIAKPLDREQLMFYNLSIIATDGKFTAKA 3067

Query: 669  STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
            +   V I ++DIND+ P           +E+  IGTT+ E++A D D       + S KG
Sbjct: 3068 N---VEIDVKDINDNTPYCLKPRYHISTNESISIGTTLVEVKAIDFDFQSKLRFYLSGKG 3124

Query: 729  GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVT-- 785
             DD   FS+    G +   L     LD E+   KY+LV           +   EI++T  
Sbjct: 3125 ADD---FSI----GKESGILKVASALDRET-TPKYKLVAHVQDGKDFTQECFSEIIITVN 3176

Query: 786  DVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLN 843
            D+NDN P+    Q   +  +D        +V A D D  V  +++Y ++ G N +   ++
Sbjct: 3177 DINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLM-GENHDYFKIS 3235

Query: 844  ETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLI 887
            ++TG + L   L+     L  + V   D GV ++ ++  ++V ++
Sbjct: 3236 KSTGIIRLHKSLDRETISLFNLTVKAEDCGVPKLHSIATVAVNIL 3280



 Score =  239 bits (586), Expect = 6e-61
 Identities = 212/827 (25%), Positives = 364/827 (44%), Gaps = 57/827 (6%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            F ID  +G++     LD EK++ + V ++ATD  S V     +   + V+I+D ND YP+
Sbjct: 2282 FEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLSGVY----AEVVLSVSIMDVNDCYPE 2337

Query: 150  FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY---AIIGGNTQMQFSIDSLS 206
                 Y +++ E+ S      I KI ATD D GAN+ + Y   +I G N    F ID   
Sbjct: 2338 IESDIYNLTIPENASFGTQ--ILKINATDNDSGANAKLSYYIESINGQNNSELFYIDVTD 2395

Query: 207  GDVSLVKTLDYEQVRSYRLVIRAQDGGSPS---RSN---TTQLL-------------INI 247
            G++ L   LDYEQ++ + +V+  +D GSPS   RSN   T ++L             I +
Sbjct: 2396 GNLYLKTPLDYEQIKYHHIVVNVKDHGSPSLSSRSNVFITGRILCRFISYKLIYDSIIPV 2455

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            +D+NDNAP F    +   VS     G  +   +AYD D      L Y    K   GN   
Sbjct: 2456 KDLNDNAPCFVEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEY----KIVYGNELQ 2511

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
              +ID  +G +     L+   ++   L ++ +DG     +A A               F 
Sbjct: 2512 TYSIDKLTGVISLQNMLNFTDKSSTVLNISVSDG---VHTAYARLKISLLPENVYSPLFD 2568

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITV 425
               YE ++ E+   G  ++T+ A+D D      L+YEI     +  F I      G+IT 
Sbjct: 2569 QSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYYEIVSEEMKKIFLIDQTT--GVITS 2626

Query: 426  AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
                D +++  YV+ +  +D GG+   A +++ + D N+  P F    Y   V       
Sbjct: 2627 KVTFDREKKDEYVVLLKVSDGGGKFGFASLKVIVVDVNDNVPYFLLKEYKMVVSTTVEAN 2686

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
             T+L V A D D+  N  + + +  + +++AV        IN +TG I      +   ++
Sbjct: 2687 QTILTVKAKDDDIVDNGSVHFQIVQKSNDKAV---KDVIEINEKTGDIVFKSKAESYGVN 2743

Query: 546  GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
             Y   V A D G P       V I +++ + N P F++      I+E    GT +++   
Sbjct: 2744 SYQFFVRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVLTK--- 2800

Query: 606  TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
                + + G   ++      ++   + D  SG +   + LDRE   +H+L  VA     P
Sbjct: 2801 ----LHMIGNYTFKFSIAADQDHFMISD--SGELILQQTLDREQQESHNLIVVAETSTVP 2854

Query: 666  PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
               +   V I + D ND+ P F++   +  ++ENS    ++ ++ A D D GPN  + Y 
Sbjct: 2855 VFFAYADVLIDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYY 2914

Query: 726  IKGGDDS--NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEIL 783
            ++   ++  N F ++   G     L+T +D + +S      +      P     V V I 
Sbjct: 2915 LESDTENIQNIFDIDIYSG--WITLLTSLDREVQSEYNFKVIAADNGHPKHDAKVPVTIK 2972

Query: 784  VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV-TDKLQYRILSGNNANLILL 842
            + D NDNAPV K      + +++  P      +   D D+   ++ + I+SG+      +
Sbjct: 2973 IVDYNDNAPVFKLPIEGLSVFENALPGTVLINLLLIDPDIEKQEMDFFIVSGDKQAQFQI 3032

Query: 843  NETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889
             + +G + ++  L+        + +  TDG    KA +++ V+ I +
Sbjct: 3033 GK-SGELFIAKPLDREQLMFYNLSIIATDGKFTAKANVEIDVKDIND 3078



 Score =  239 bits (585), Expect = 8e-61
 Identities = 229/846 (27%), Positives = 368/846 (43%), Gaps = 88/846 (10%)

Query: 86   VQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145
            + + FRI+  +G ++   ++D E +  + + VK T+ A+      SS   I ++I+D ND
Sbjct: 1753 INESFRINPSTGVIVINGNIDYESIKVFNLTVKGTNMAAE-----SSCQNIIIHILDAND 1807

Query: 146  NYPQFSEKTYTVSVDEDISVTDNPVIAK--------IKATDADVGANSAIRYAIIGGNTQ 197
            N P F +  Y  ++ E  ++    +           ++  DADVG N  + Y I+    +
Sbjct: 1808 NIPYFVQNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVKDADVGVNGMVEYHIVDDLAK 1867

Query: 198  MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR--DVNDNAP 255
              F IDS +G + L++ LDYE    Y   +   D G P   +TT   + IR  +VND  P
Sbjct: 1868 NFFKIDSTTGAIELLRQLDYETNAGYTFDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPP 1927

Query: 256  RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315
             F       ++         + +V A DAD   N  L + + D    GN +    I+  +
Sbjct: 1928 VFNERELNVTLFLPTFENVFVRQVSAKDAD---NDTLRFDIVD----GNTNECFQIEKYT 1980

Query: 316  GWVYTSGQ--LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373
            G + T     L+ E    Y L V A+DG     SA                 F    Y  
Sbjct: 1981 GIITTRNFEILNNENDRDYALHVRASDG---IFSAILIVKIKVLSAIDSNFAFQRESYRF 2037

Query: 374  ELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ 433
               E+      +  +       D  + Y I   N    F I   +G  L T     D + 
Sbjct: 2038 SAFENNTKVATIGLVNVIGNTLDENVEYRIL--NPTQLFDIGISSG-ALKTTGVIFDREV 2094

Query: 434  ERRYVLTVSAT-------DSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
            +  Y L V A        +S  R     + I++ D N+  P+F N PY A+V  D P GT
Sbjct: 2095 KDLYRLFVEAKSMLYDGMNSNVRRAVTSIDISVLDVNDNCPLFVNMPYYATVSIDDPKGT 2154

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
             ++ V A D D   N ++ Y L           + + F ++ ++G ++  + ++    + 
Sbjct: 2155 IIMQVKAIDLDSAENGEVRYELKKG--------NGELFKLDRKSGELSIKQHVEGHNRN- 2205

Query: 547  YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
            Y LTV A DG +   S    +++ V+D   + PVF++Q YT ++ ED  + +++S   + 
Sbjct: 2206 YELTVAAYDGAITPCSSEAPLQVKVID--RSMPVFEKQFYTVSVKEDVEMYSALSV--SI 2261

Query: 607  DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
            +A+  L   + Y +     E  SF ID  +G I     LD E +++HD+   A D  +  
Sbjct: 2262 EAESPLGRSLIYTISS---ESQSFEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLSGV 2318

Query: 667  QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY-- 724
             +  V++ + I D+ND  P  ESD     I EN+  GT I +I A D D G NA + Y  
Sbjct: 2319 YAE-VVLSVSIMDVNDCYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYI 2377

Query: 725  -SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRV 780
             SI G ++S  F ++   G+    L     LDYE   K + +V+      SP L +   V
Sbjct: 2378 ESINGQNNSELFYIDVTDGN----LYLKTPLDYEQ-IKYHHIVVNVKDHGSPSLSSRSNV 2432

Query: 781  EIL-------------------VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVP-AYD 820
             I                    V D+NDNAP   +    F         G F  +P AYD
Sbjct: 2433 FITGRILCRFISYKLIYDSIIPVKDLNDNAPCFVE-PSYFTKVSVAAVRGQFVALPKAYD 2491

Query: 821  ADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKA 878
             D+  TD L+Y+I+ GN      +++ TG ++L   LN        + +SV+DGV+   A
Sbjct: 2492 KDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQNMLNFTDKSSTVLNISVSDGVHTAYA 2551

Query: 879  MMQLSV 884
             +++S+
Sbjct: 2552 RLKISL 2557



 Score =  236 bits (578), Expect = 6e-60
 Identities = 191/635 (30%), Positives = 298/635 (46%), Gaps = 28/635 (4%)

Query: 234  SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293
            SPS  +   L  +    N + P F     + S++E+V +G ++  ++A D D G N +L 
Sbjct: 746  SPSVFSDLSLTPSRYGQNVHRPEFVNFPQELSINESVQLGETVAWIEAKDRDLGYNGKLV 805

Query: 294  YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353
            + ++D DY    D    IDP  G +   G LDRE Q +Y L +T  D G+P +S +    
Sbjct: 806  FAISDGDY----DSVFRIDPDRGELQIIGYLDRERQNEYVLNITVYDLGNPTKSTSKMLP 861

Query: 354  XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS 413
                                 L E    GT V  L ATDA  D+ ++ ++T   +     
Sbjct: 862  ITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHATDA--DSGINAQVTYALSVECSD 919

Query: 414  ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFEN 471
             T     G + + +PLD +++  Y L ++A D G    S  A+V + + D N+ APVF  
Sbjct: 920  FTVNATTGCLRLNKPLDREKQDNYALHITAKDGGSPVLSSEALVYVLVDDVNDNAPVFGV 979

Query: 472  APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
              Y   V ED P GT + V+ A D D+G NA+I +SL  E  +E      + F I+  TG
Sbjct: 980  QEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSLKEETQDE------ELFRIDKHTG 1033

Query: 532  AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE--PVFKQQLYTAN 589
            AI T   LD E    + L V+A DGG PSL+    + I ++DVN+N   P F   +Y   
Sbjct: 1034 AIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMIIDVNENRFAPEFDDFVYEGK 1093

Query: 590  IMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648
            + E+   GT V  V A D D V LN +I Y +   D   G F ++   G I +   LD E
Sbjct: 1094 VKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGD-GLGIFAVND-QGSITSLSQLDAE 1151

Query: 649  SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
            +   + L   A D    P S+ V V+I++E+ ND+ P+ +       ++E S     I  
Sbjct: 1152 TKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVENVEIIT 1211

Query: 709  IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK-YELVI 767
            ++A DPD  P   + Y+I  G+    F ++++ G  K    T   LD E+  +   E+ I
Sbjct: 1212 LKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTGVIK---TTERKLDRENQAEHILEVAI 1268

Query: 768  R-AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTD 825
                SP L +  R+ + V D+NDN+P   D ++          V     +V A D+D  +
Sbjct: 1269 SDNGSPVLSSTSRIVVSVLDINDNSPEF-DQRVYKVQVPSSATVNQSIFQVHAIDSDSGE 1327

Query: 826  --KLQYRILSGNNANLILLNETTGSMTLSPQLNTN 858
              ++ Y I SG   N   ++   G + ++  L+++
Sbjct: 1328 NGRITYSIKSGKGKNKFRIDSQRGHIHIAKPLDSD 1362



 Score =  229 bits (561), Expect = 6e-58
 Identities = 235/908 (25%), Positives = 392/908 (43%), Gaps = 89/908 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I+VLD ND+ P+F    Y A+V      GT ++ +KA D D  +N EV Y ++       
Sbjct: 2125 ISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVKAIDLDSAENGEVRYELKKGNG--- 2181

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                             ++F++D +SG L  +  ++      Y + V A D A       
Sbjct: 2182 -----------------ELFKLDRKSGELSIKQHVEGHN-RNYELTVAAYDGA---ITPC 2220

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            SS A + V +ID   + P F ++ YTVSV ED+ +      A   + +A+     ++ Y 
Sbjct: 2221 SSEAPLQVKVID--RSMPVFEKQFYTVSVKEDVEMYS----ALSVSIEAESPLGRSLIYT 2274

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I   +    F ID  +G + +V  LDYE++ S+ + IRA D  S   +    L ++I DV
Sbjct: 2275 I--SSESQSFEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLSGVYAEVV-LSVSIMDV 2331

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            ND  P   + ++  ++ EN   G  I+++ A D D G NA+L+Y +   +   N +L   
Sbjct: 2332 NDCYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSEL-FY 2390

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX----- 365
            ID   G +Y    LD E    + ++V   D G P  S+ +                    
Sbjct: 2391 IDVTDGNLYLKTPLDYEQIKYHHIVVNVKDHGSPSLSSRSNVFITGRILCRFISYKLIYD 2450

Query: 366  --------------FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTR 409
                          F+   Y  +++     G  V    A D D  + + L Y+I  GN  
Sbjct: 2451 SIIPVKDLNDNAPCFVEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKIVYGNEL 2510

Query: 410  GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVF 469
              +SI      G+I++   L+F  +   VL +S +D G  +  A ++I++   N Y+P+F
Sbjct: 2511 QTYSIDKLT--GVISLQNMLNFTDKSSTVLNISVSD-GVHTAYARLKISLLPENVYSPLF 2567

Query: 470  ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
            + + Y A V E+   G  ++ V A+D D G  A + Y + SE   +        F+I+  
Sbjct: 2568 DQSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYYEIVSEEMKKI-------FLIDQT 2620

Query: 530  TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589
            TG IT+    DRE    Y++ +   DGG         +++ VVDVNDN P F  + Y   
Sbjct: 2621 TGVITSKVTFDREKKDEYVVLLKVSDGG--GKFGFASLKVIVVDVNDNVPYFLLKEYKMV 2678

Query: 590  IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG---SFVIDPASGVIRTNKALD 646
            +        ++  V A D D+  NG +H+++  K  ++       I+  +G I      +
Sbjct: 2679 VSTTVEANQTILTVKAKDDDIVDNGSVHFQIVQKSNDKAVKDVIEINEKTGDIVFKSKAE 2738

Query: 647  RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706
               V ++     A D G P   S V V I+I + + + P FE   +   I E++P GT +
Sbjct: 2739 SYGVNSYQFFVRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVL 2798

Query: 707  GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV 766
             ++         N    +SI    D + F +     SD  EL+    LD E       +V
Sbjct: 2799 TKLHMIG-----NYTFKFSIAA--DQDHFMI-----SDSGELILQQTLDREQQESHNLIV 2846

Query: 767  IRAAS--PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV- 823
            +   S  P  +    V I V D NDN P   +     +  ++   V    +V A DAD  
Sbjct: 2847 VAETSTVPVFFAYADVLIDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTG 2906

Query: 824  -TDKLQYRILSG--NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAM 879
                ++Y + S   N  N+  ++  +G +TL   L+  V      +V   D G  +  A 
Sbjct: 2907 PNGDIRYYLESDTENIQNIFDIDIYSGWITLLTSLDREVQSEYNFKVIAADNGHPKHDAK 2966

Query: 880  MQLSVRLI 887
            + ++++++
Sbjct: 2967 VPVTIKIV 2974



 Score =  195 bits (475), Expect = 2e-47
 Identities = 178/641 (27%), Positives = 288/641 (44%), Gaps = 48/641 (7%)

Query: 133 TATIHVNIIDDNDNYPQFSEKTYTVSVDED-ISVTDNPVIAKIKATDADVGANSAIRYAI 191
           TAT+   + +   +  +FS   Y V++ E+ +  T    +   +     VG N+ ++Y I
Sbjct: 42  TATLEYRLENQLQDLYRFSHSVYNVTIPENSLGKTYAKGVLHERLAGLRVGLNAEVKYRI 101

Query: 192 IGGNTQMQFSIDS-LSGDVSL--VKT------LDYEQVRSYRLVIRAQ----DGGSPSRS 238
           I G+ +  F  +  L GD +   ++T      L+ E+   Y + ++A     D    S  
Sbjct: 102 ISGDKEKLFKAEEKLVGDFAFLAIRTRTNNVVLNREKTEEYVIRVKAHVHLHDRNVSSYE 161

Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT-MT 297
               + I + D ND +P FY + +   + E+ P   SI++V A DAD G+N E+ Y+ + 
Sbjct: 162 TEANIHIKVLDRNDLSPLFYPTQYTVVIPEDTPKYQSILKVTADDADLGINGEIYYSLLM 221

Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357
           D +Y         I P +G +    QL     + ++L V A D G               
Sbjct: 222 DSEY-------FAIHPTTGEITLLQQLQYAENSHFELTVVAYDRGSWVNHQNHQASKTKV 274

Query: 358 XXXXXXXXF-MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH-----YEITGGNTRGR 411
                   F  P  +    +   P   P++       D+D  ++      EI  GN  G 
Sbjct: 275 SISVKQVNFYAPEIFTKTFSSVTPTSNPLIYGIVRVNDKDTGINGNIGRLEIVDGNPDGT 334

Query: 412 FSITSQNGRG--LITVAQPLDFKQER-RYVLTVSATDSG--GRSDTAMVQINITDANNYA 466
           F + +   +    I + Q     Q+   Y LT+ A D G   R     V I I   +   
Sbjct: 335 FLLKAAETKDEYYIELNQFAHLNQQHFIYNLTLLAEDLGTPRRFAYKSVPIQIKPESKNI 394

Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
           P+F    Y  S+ E API   V+ +  +D D+G NA +   +     NE       +F I
Sbjct: 395 PIFTQEIYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVG--GNEG-----DEFRI 447

Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARD-GGVPSLSDTT-DVEISVVDVNDNEPVFKQQ 584
           NP +G + T K LD E  S Y LTV+A D   V S   ++  V+ISV D+NDN+P+F+  
Sbjct: 448 NPDSGMLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIFENV 507

Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA 644
               +I E+ L G+ V ++ A D D G N  I Y +   +     F ID  SG+++T   
Sbjct: 508 NKVISINENNLAGSFVVKLTAKDRDSGENSYISYSI--ANLNAVPFEIDHFSGIVKTTSL 565

Query: 645 LDRESV-ATHDLKAVAIDGGTPPQSSTVI-VHIKIEDINDSPPVFESDCLTFYISENSPI 702
           LD E++   ++L   A D G P +  T I + I ++DIND+ P FE       +++++P+
Sbjct: 566 LDFETMKRNYELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFERVNCYGKVTKSAPM 625

Query: 703 GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
           GT +    A D D G   ++ Y +  G++   F+L+   GS
Sbjct: 626 GTEVFVTSAIDFDAGD--IISYRLSDGNEDGCFNLDPTSGS 664



 Score =  176 bits (429), Expect = 6e-42
 Identities = 153/552 (27%), Positives = 255/552 (46%), Gaps = 51/552 (9%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLI 423
           F P QY V + ED P    ++ +TA DAD   +  ++Y +   +    F+I    G   I
Sbjct: 180 FYPTQYTVVIPEDTPKYQSILKVTADDADLGINGEIYYSLLMDSEY--FAIHPTTGE--I 235

Query: 424 TVAQPLDFKQERRYVLTVSATDSGG-------RSDTAMVQINITDANNYAPVFENAPYTA 476
           T+ Q L + +   + LTV A D G        ++    V I++   N YAP      +++
Sbjct: 236 TLLQQLQYAENSHFELTVVAYDRGSWVNHQNHQASKTKVSISVKQVNFYAPEIFTKTFSS 295

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITY------SLSSEISNEAVAHHDQQFVINPQT 530
                 P+     +V   D D GIN  I        +       +A    D+ ++   Q 
Sbjct: 296 VTPTSNPL--IYGIVRVNDKDTGINGNIGRLEIVDGNPDGTFLLKAAETKDEYYIELNQF 353

Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590
             +     +       Y LT+ A D G P       V I +   + N P+F Q++Y  +I
Sbjct: 354 AHLNQQHFI-------YNLTLLAEDLGTPRRFAYKSVPIQIKPESKNIPIFTQEIYEVSI 406

Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650
            E A +   V ++  +D D+G N  ++ E+     E   F I+P SG++ T K LD E  
Sbjct: 407 PETAPINMPVIRLKVSDPDLGKNALVYLEI-VGGNEGDEFRINPDSGMLYTAKQLDAEKK 465

Query: 651 ATHDLKAVAIDG---GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
           +++ L   AID    G+  QSS   V I ++D+ND+ P+FE+      I+EN+  G+ + 
Sbjct: 466 SSYTLTVSAIDQANVGSRKQSSAK-VKISVQDMNDNDPIFENVNKVISINENNLAGSFVV 524

Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
           ++ A D D G N+ + YSI    + N+   E    S   +  ++  LD+E+ ++ YEL+I
Sbjct: 525 KLTAKDRDSGENSYISYSIA---NLNAVPFEIDHFSGIVKTTSL--LDFETMKRNYELII 579

Query: 768 RAASPPL----WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR----VPAY 819
           RA+   L      ++++ I+V D+NDN P    F+ + N Y       P G       A 
Sbjct: 580 RASDWGLPYRRQTEIKLSIVVKDINDNRP---QFERV-NCYGKVTKSAPMGTEVFVTSAI 635

Query: 820 DADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAM 879
           D D  D + YR+  GN      L+ T+GS+++S  L         ++VS TDG +    +
Sbjct: 636 DFDAGDIISYRLSDGNEDGCFNLDPTSGSLSISCDLKKTTLTNRILKVSATDGTHFSDDL 695

Query: 880 MQLSVRLITEEM 891
           + ++V L+ E++
Sbjct: 696 I-INVHLMPEDL 706



 Score =  155 bits (376), Expect = 2e-35
 Identities = 153/563 (27%), Positives = 252/563 (44%), Gaps = 59/563 (10%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I VLD ND SP+F   QY   + E      ++L + A D D+G N E+ Y++ + +    
Sbjct: 168 IKVLDRNDLSPLFYPTQYTVVIPEDTPKYQSILKVTADDADLGINGEIYYSLLMDS---- 223

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS--D 128
                            + F I   +G +     L   + + + + V A D+ S V+  +
Sbjct: 224 -----------------EYFAIHPTTGEITLLQQLQYAENSHFELTVVAYDRGSWVNHQN 266

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVI-AKIKATDADVGANSAI 187
             +S   + +++   N   P+   KT++      ++ T NP+I   ++  D D G N  I
Sbjct: 267 HQASKTKVSISVKQVNFYAPEIFTKTFS-----SVTPTSNPLIYGIVRVNDKDTGINGNI 321

Query: 188 -RYAIIGGNTQMQFSIDSL-SGDVSLVKTLDYEQVRS----YRLVIRAQDGGSPSRSNTT 241
            R  I+ GN    F + +  + D   ++   +  +      Y L + A+D G+P R    
Sbjct: 322 GRLEIVDGNPDGTFLLKAAETKDEYYIELNQFAHLNQQHFIYNLTLLAEDLGTPRRFAYK 381

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
            + I I+  + N P F   +++ S+ E  PI   ++R++  D D G NA L Y    +  
Sbjct: 382 SVPIQIKPESKNIPIFTQEIYEVSIPETAPINMPVIRLKVSDPDLGKNA-LVYL---EIV 437

Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD--PPRSATATXXXXXXXX 359
            GN      I+P SG +YT+ QLD E ++ Y L V+A D  +    + ++A         
Sbjct: 438 GGNEGDEFRINPDSGMLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDM 497

Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQ 417
                 F      + + E+   G+ VV LTA D D  E++ + Y I   N    F I   
Sbjct: 498 NDNDPIFENVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSIANLNA-VPFEI--D 554

Query: 418 NGRGLITVAQPLDFK-QERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAP 473
           +  G++     LDF+  +R Y L + A+D G    R     + I + D N+  P FE   
Sbjct: 555 HFSGIVKTTSLLDFETMKRNYELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFERVN 614

Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
               V + AP+GT V V SA D D G    I+Y LS    NE     D  F ++P +G++
Sbjct: 615 CYGKVTKSAPMGTEVFVTSAIDFDAG--DIISYRLSD--GNE-----DGCFNLDPTSGSL 665

Query: 534 TTNKLLDRETMSGYLLTVTARDG 556
           + +  L + T++  +L V+A DG
Sbjct: 666 SISCDLKKTTLTNRILKVSATDG 688



 Score =  120 bits (290), Expect = 4e-25
 Identities = 105/360 (29%), Positives = 164/360 (45%), Gaps = 33/360 (9%)

Query: 453 AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512
           A + I + D N+ +P+F    YT  + ED P   ++L V+A D+D+GIN +I YSL  + 
Sbjct: 164 ANIHIKVLDRNDLSPLFYPTQYTVVIPEDTPKYQSILKVTADDADLGINGEIYYSLLMD- 222

Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG-----VPSLSDTTDV 567
                    + F I+P TG IT  + L     S + LTV A D G         +  T V
Sbjct: 223 --------SEYFAIHPTTGEITLLQQLQYAENSHFELTVVAYDRGSWVNHQNHQASKTKV 274

Query: 568 EISVVDVNDNEP-VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE 626
            ISV  VN   P +F +   +     + L+      V   D D G+NG I          
Sbjct: 275 SISVKQVNFYAPEIFTKTFSSVTPTSNPLI---YGIVRVNDKDTGINGNIGRLEIVDGNP 331

Query: 627 EGSFVIDPASG----VIRTNK-ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681
           +G+F++  A       I  N+ A   +    ++L  +A D GTP + +   V I+I+  +
Sbjct: 332 DGTFLLKAAETKDEYYIELNQFAHLNQQHFIYNLTLLAEDLGTPRRFAYKSVPIQIKPES 391

Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741
            + P+F  +     I E +PI   +  ++  DPD G NA+V+  I GG++ + F    R 
Sbjct: 392 KNIPIFTQEIYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVGGNEGDEF----RI 447

Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRA-----ASPPLWNDVRVEILVTDVNDNAPVMKD 796
             D   L T   LD E  +  Y L + A           +  +V+I V D+NDN P+ ++
Sbjct: 448 NPDSGMLYTAKQLDAEK-KSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIFEN 506



 Score = 97.5 bits (232), Expect = 5e-18
 Identities = 116/456 (25%), Positives = 190/456 (41%), Gaps = 27/456 (5%)

Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI---TTNKLLDRETMSGYLLTVTAR 554
           VG+NA++ Y + S    E +   +++ V +    AI   T N +L+RE    Y++ V A 
Sbjct: 91  VGLNAEVKYRIISG-DKEKLFKAEEKLVGDFAFLAIRTRTNNVVLNREKTEEYVIRVKAH 149

Query: 555 ----DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610
               D  V S     ++ I V+D ND  P+F    YT  I ED     S+ +V A DAD+
Sbjct: 150 VHLHDRNVSSYETEANIHIKVLDRNDLSPLFYPTQYTVVIPEDTPKYQSILKVTADDADL 209

Query: 611 GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT-----P 665
           G+NG I+Y L   D E   F I P +G I   + L     +  +L  VA D G+      
Sbjct: 210 GINGEIYYSL-LMDSE--YFAIHPTTGEITLLQQLQYAENSHFELTVVAYDRGSWVNHQN 266

Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA-VVHY 724
            Q+S   V I ++ +N   P   +   +     ++P+    G +R +D D G N  +   
Sbjct: 267 HQASKTKVSISVKQVNFYAPEIFTKTFSSVTPTSNPL--IYGIVRVNDKDTGINGNIGRL 324

Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVE 781
            I  G+   +F L+  +  D+  +              Y L + A    +P  +    V 
Sbjct: 325 EIVDGNPDGTFLLKAAETKDEYYIELNQFAHLNQQHFIYNLTLLAEDLGTPRRFAYKSVP 384

Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADV-TDKLQY-RILSGNNAN 838
           I +   + N P+    +I   +  +  P+  P  R+   D D+  + L Y  I+ GN  +
Sbjct: 385 IQIKPESKNIPIFTQ-EIYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVGGNEGD 443

Query: 839 LILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN-EIKAMMQLSVRLITEEMLLNSIT 897
              +N  +G +  + QL+       T+ VS  D  N   +      V++  ++M  N   
Sbjct: 444 EFRINPDSGMLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPI 503

Query: 898 VRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYI 933
               +       + L G F+  L A      EN YI
Sbjct: 504 FENVNKVISINENNLAGSFVVKLTAKDRDSGENSYI 539



 Score = 70.1 bits (164), Expect = 8e-10
 Identities = 63/225 (28%), Positives = 101/225 (44%), Gaps = 29/225 (12%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +I+V D ND+ P+FE      S+ E   +G+ V+ L A D+D G+N+ + Y+I  + A  
Sbjct: 491 KISVQDMNDNDPIFENVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSIANLNAVP 550

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSD 128
                               F ID  SG + T + LD E + R Y ++++A+D   P   
Sbjct: 551 --------------------FEIDHFSGIVKTTSLLDFETMKRNYELIIRASDWGLPY-- 588

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA-DVGANSAI 187
           R  +   + + + D NDN PQF        V +       P+  ++  T A D  A   I
Sbjct: 589 RRQTEIKLSIVVKDINDNRPQFERVNCYGKVTKSA-----PMGTEVFVTSAIDFDAGDII 643

Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232
            Y +  GN    F++D  SG +S+   L    + +  L + A DG
Sbjct: 644 SYRLSDGNEDGCFNLDPTSGSLSISCDLKKTTLTNRILKVSATDG 688



 Score = 44.0 bits (99), Expect = 0.061
 Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 4/52 (7%)

Query: 1535 STCTCEAGRVGPQC---VSACELGPCGAAR-CVPDQTPKGYSCACEPGYTLT 1582
            +TC C  G  G  C   V+AC   PC   R C+P  +  GY C C  G++ T
Sbjct: 3865 NTCVCRPGFDGKHCKETVNACSTDPCSPQRICMPSGSALGYQCVCPKGFSGT 3916


>UniRef50_A6NIM4 Cluster: Uncharacterized protein FAT3; n=43;
            Euteleostomi|Rep: Uncharacterized protein FAT3 - Homo
            sapiens (Human)
          Length = 4558

 Score =  433 bits (1066), Expect = e-119
 Identities = 389/1370 (28%), Positives = 612/1370 (44%), Gaps = 126/1370 (9%)

Query: 1    MSVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEY 60
            + + F +   I VLD ND+ PVFE   Y+  + EG   GT +  ++A D D G N +V Y
Sbjct: 2793 VDIVFTVDVDIKVLDLNDNKPVFETSSYDTIIMEGMPVGTKLTQVRAIDMDWGANGQVTY 2852

Query: 61   TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT 120
            ++    +D+  PE            V + F ID  +G + T   LD E    +T  V A+
Sbjct: 2853 SLH---SDS-QPEK-----------VMEAFNIDSNTGWISTLKDLDHETDPTFTFSVVAS 2897

Query: 121  DQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD 180
            D     S  LSSTA + V + D NDN P F+++ Y  +V E  S     V+A +   D D
Sbjct: 2898 DLGEAFS--LSSTALVSVRVTDINDNAPVFAQEVYRGNVKE--SDPPGEVVAVLSTWDRD 2953

Query: 181  VG-ANSAIRYAIIGGNTQMQFSIDSLSGD--VSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237
                N  + Y I GGN + +F++  +  +  V + + LD E+   Y L I A DG   ++
Sbjct: 2954 TSDVNRQVSYHITGGNPRGRFALGLVQSEWKVYVKRPLDREEQDIYFLNITATDGLFVTQ 3013

Query: 238  SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297
            +    + +++ DVNDN+P      +   + E++P    I++V A DAD G N  + Y++ 
Sbjct: 3014 A---MVEVSVSDVNDNSPVCDQVAYTALLPEDIPSNKIILKVSAKDADIGSNGYIRYSLY 3070

Query: 298  DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357
                +GN +    +DP SG + T   LDRE    Y L+  ATDGG   R   +       
Sbjct: 3071 G---SGNSEF--FLDPESGELKTLALLDRERIPVYSLMAKATDGGG--RFCQSNIHLILE 3123

Query: 358  XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITS 416
                    F    Y   + E+      +  + A D D   NR        +  G FSI S
Sbjct: 3124 DVNDNPPVFSSDHYNTCVYENTATKALLTRVQAVDPDIGINRKVVYSLADSAGGVFSIDS 3183

Query: 417  QNGRGLITVAQPLDFKQERRYVLTVSATD-SGGRSDTAMVQINIT--DANNYAPVFENAP 473
             +G  +I + QPLD +Q+  Y ++V ATD S G+S +++  + IT  D N+  PVFE   
Sbjct: 3184 SSG--IIILEQPLDREQQSSYNISVRATDQSPGQSLSSLTTVTITVLDINDNPPVFERRD 3241

Query: 474  YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
            Y  +V ED   GT VL V AT  D+G NA+ITY + S   NE       +F INP+TG I
Sbjct: 3242 YLVTVPEDTSPGTQVLAVFATSKDIGTNAEITYLIRS--GNE-----QGKFKINPKTGGI 3294

Query: 534  TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593
            + +++LD E    + L V A+DGG P+LS    V I++ DVNDN P F Q +Y+A I ED
Sbjct: 3295 SVSEVLDYELCKRFYLVVEAKDGGTPALSAVATVNINLTDVNDNPPKFSQDVYSAVISED 3354

Query: 594  ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653
            ALVG SV  + A D D   NG+IH+ +   DR +  F +DP  G+++  K LDRE V+ +
Sbjct: 3355 ALVGDSVILLIAEDVDSQPNGQIHFSIVNGDR-DNEFTVDPVLGLVKVKKKLDRERVSGY 3413

Query: 654  DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713
             L   A+D G P  SST  V+I I D+ND+ PVF     T  I EN P+GT+I ++   D
Sbjct: 3414 SLLVQAVDSGIPAMSSTATVNIDISDVNDNSPVFTPANYTAVIQENKPVGTSILQLVVTD 3473

Query: 714  PDEGPNA-VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA--- 769
             D   N     +SI  G++   F L+   G  ++ +V        +   +Y L ++A   
Sbjct: 3474 RDSFHNGPPFSFSILSGNEEEEFVLDP-HGILRSAVVFQ-----HTESLEYVLCVQAKDS 3527

Query: 770  ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQY 829
              P   +   + + V + + + P     +I     +D FP G  G++ A D D+ D L +
Sbjct: 3528 GKPQQVSHTYIRVRVIEESTHKPTAIPLEIFIVTMEDDFPGGVIGKIHATDQDMYDVLTF 3587

Query: 830  RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889
              L     +L  +N   G +     L++       + VSV+DG  ++   + + V  +  
Sbjct: 3588 -ALKSEQKSLFKVNSHDGKIIALGGLDSG---KYVLNVSVSDGRFQVPIDVVVHVEQLVH 3643

Query: 890  EMLLNSITVRLNDMTAEQFLS-PLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTG-NIL 947
            EML N++T+R  +++ E F+   + GF      A++   ++++ I S+Q    V G N L
Sbjct: 3644 EMLQNTVTIRFENVSPEDFVGLHMHGFRRTLRNAVLTQKQDSLRIISIQ---PVAGTNQL 3700

Query: 948  NVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPC 1007
            ++ F+     +E          Y P +L +++   R  L  +  +  +  + N C    C
Sbjct: 3701 DMLFAVEMHSSE---------FYKPAYLIQKLSNARRHLENIMRISAI-LEKN-CSGLDC 3749

Query: 1008 LNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVD 1067
               + C   L        ++S +++    Y     +  CP  +  V C        C   
Sbjct: 3750 QE-QHCEQGLS-------LDSHALM---TYSTARISFVCPRFYRNVRC--TCNGGLCPGS 3796

Query: 1068 GDGSI---CRSGSQCVARREG--GILCQGCSIDAAYTTAVCELRARSFPVSSFLTF--PG 1120
             D  +   C    QCV+        LCQ         +    L   SF  +S++ +    
Sbjct: 3797 NDPCVEKPCPGDMQCVSYEASRRPFLCQCPPGKLGECSGHTSL---SFAGNSYIKYRLSE 3853

Query: 1121 LKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRGGGPGLRFSFSLGG 1180
              +     L L+  T  ++G+++    Y   +  + L++V  +        L F    G 
Sbjct: 3854 NSKEEDFKLALRLRTLQSNGIIM----YTRANPCIILKIVDGK--------LWFQLDCGS 3901

Query: 1181 GKSEITVEGN-VGDGSWHTVEIEYFNRTITMILDDCDKVLSLAGAADFGLKYACANFTRK 1239
            G   + + G  V DGSWH+V +E  NR  T +  D D  +    A      Y     T  
Sbjct: 3902 GPGILGISGRAVNDGSWHSVFLE-LNRNFTSLSLD-DSYVERRRAP----LYFQTLSTES 3955

Query: 1240 VLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNS 1299
             +     +  +      D      + G      S  + N       ++  + +K      
Sbjct: 3956 SIYFGALVQADNIRSLTDTRVTQVLSGFQGCLDSVILNN-------NELPLQNKRSSFAE 4008

Query: 1300 YVADNGTLAGCPEKRSRCSSAPCYNGAECSDL-WDTYICDCKEGHTGKDC 1348
             V       GC      C  +PC +G  C+ L    Y C C    TG++C
Sbjct: 4009 VVGLTELKLGCVLYPDACKRSPCQHGGSCTGLPSGGYQCTCLSQFTGRNC 4058



 Score =  339 bits (834), Expect = 5e-91
 Identities = 241/798 (30%), Positives = 382/798 (47%), Gaps = 51/798 (6%)

Query: 5    FCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIEL 64
            FC  + I V+D ND++P F   +Y ASVR     G  V  ++A D D G N+ + Y++  
Sbjct: 2584 FCTVRVI-VVDENDNAPQFMTVEYRASVRADVGRGHLVTQVQAIDPDDGANSRITYSL-- 2640

Query: 65   VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS 124
                                 V D+  ID  +G ++T+ + ++ K    +  VKA D   
Sbjct: 2641 --------------YSEASVSVADLLEIDPDNGWMVTKGNFNQLKNTVLSFFVKAVDGGI 2686

Query: 125  PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184
            PV     S   ++++++      P F++  Y+ ++ ED ++     +  ++   +     
Sbjct: 2687 PVK---HSLIPVYIHVLPPETFLPSFTQSQYSFTIAEDTAI--GSTVDTLRILPSQNVWF 2741

Query: 185  SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ-DGGSPSRSNTTQL 243
            S +       N    F I+  +G + L K LD E   ++   + A           T  +
Sbjct: 2742 STVNGERPENNKGGIFVIEQETGTIKLDKRLDRETSPAFHFKVAATIPLDKVDIVFTVDV 2801

Query: 244  LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
             I + D+NDN P F TS +   + E +P+G  + +V+A D D G N ++TY++       
Sbjct: 2802 DIKVLDLNDNKPVFETSSYDTIIMEGMPVGTKLTQVRAIDMDWGANGQVTYSLHSDSQPE 2861

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSATATXXXXXXXXXXX 362
             V     ID  +GW+ T   LD ET   +   V A+D G+    S+TA            
Sbjct: 2862 KVMEAFNIDSNTGWISTLKDLDHETDPTFTFSVVASDLGEAFSLSSTALVSVRVTDINDN 2921

Query: 363  XXXFMPGQYEVELAEDEPPGTPVVTLTATD---ADEDNRLHYEITGGNTRGRFSITSQNG 419
               F    Y   + E +PPG  V  L+  D   +D + ++ Y ITGGN RGRF++     
Sbjct: 2922 APVFAQEVYRGNVKESDPPGEVVAVLSTWDRDTSDVNRQVSYHITGGNPRGRFALGLVQS 2981

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479
               + V +PLD +++  Y L ++ATD G     AMV+++++D N+ +PV +   YTA + 
Sbjct: 2982 EWKVYVKRPLDREEQDIYFLNITATD-GLFVTQAMVEVSVSDVNDNSPVCDQVAYTALLP 3040

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
            ED P    +L VSA D+D+G N  I YSL    ++E        F ++P++G + T  LL
Sbjct: 3041 EDIPSNKIILKVSAKDADIGSNGYIRYSLYGSGNSE--------FFLDPESGELKTLALL 3092

Query: 540  DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
            DRE +  Y L   A DGG       +++ + + DVNDN PVF    Y   + E+      
Sbjct: 3093 DRERIPVYSLMAKATDGG--GRFCQSNIHLILEDVNDNPPVFSSDHYNTCVYENTATKAL 3150

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
            +++V A D D+G+N ++ Y L   D   G F ID +SG+I   + LDRE  +++++   A
Sbjct: 3151 LTRVQAVDPDIGINRKVVYSL--ADSAGGVFSIDSSSGIIILEQPLDREQQSSYNISVRA 3208

Query: 660  IDGGTPPQ--SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
             D  +P Q  SS   V I + DIND+PPVFE       + E++  GT +  + A   D G
Sbjct: 3209 TD-QSPGQSLSSLTTVTITVLDINDNPPVFERRDYLVTVPEDTSPGTQVLAVFATSKDIG 3267

Query: 718  PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPL 774
             NA + Y I+ G++   F +  + G      V    LDYE   K++ LV+ A    +P L
Sbjct: 3268 TNAEITYLIRSGNEQGKFKINPKTGGISVSEV----LDYEL-CKRFYLVVEAKDGGTPAL 3322

Query: 775  WNDVRVEILVTDVNDNAP 792
                 V I +TDVNDN P
Sbjct: 3323 SAVATVNINLTDVNDNPP 3340



 Score =  313 bits (768), Expect = 5e-83
 Identities = 236/751 (31%), Positives = 361/751 (48%), Gaps = 52/751 (6%)

Query: 157  VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLD 216
            V+V ED+ V  N  I KIKA DAD G N  + + I  GNT   F+ID  +G + ++  +D
Sbjct: 734  VAVKEDLPVGAN--ILKIKAYDADSGFNGKVLFTISDGNTDSCFNIDMETGQLKVLMPMD 791

Query: 217  YEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSI 276
             E    Y L I   D G+P +S+   L IN+ D NDN+P F    +  ++ E+  IG  I
Sbjct: 792  REHTDLYLLNITIYDLGNPQKSSWRLLTINVEDANDNSPVFIQDSYSVNILESSGIGTEI 851

Query: 277  VRVQAYDADEGVNAELTYT-MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL 335
            ++V+A D D G N E+TY+ +TD            I+  +G VY + QLDRE++A Y L 
Sbjct: 852  IQVEARDKDLGSNGEVTYSVLTDTQ-------QFAINSSTGIVYVADQLDRESKANYSLK 904

Query: 336  VTATDGGDPPRS--ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393
            + A D  +  +   +  T              F+P  Y V++ ED P GT +  L   D 
Sbjct: 905  IEARDKAESGQQLFSVVTLKVFLDDVNDCSPAFIPSSYSVKVLEDLPVGTVIAWLETHDP 964

Query: 394  D--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG---G 448
            D     ++ Y +   +  GRF I      G I +++ LD+++++ Y LTV A D G    
Sbjct: 965  DLGLGGQVRYSLV-NDYNGRFEI--DKASGAIRLSKELDYEKQQFYNLTVRAKDKGRPVS 1021

Query: 449  RSDTAMVQINITDANN--YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506
             S  + V++ + D N   + P F +     SV E++ IGT+VL V+A D D G + +I Y
Sbjct: 1022 LSSVSFVEVEVVDVNENLHTPYFPDFAVVGSVKENSRIGTSVLQVTARDEDSGRDGEIQY 1081

Query: 507  SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566
            S+        +     +F I+ ++G IT   +LDRETM  Y LTV A D GV  L  T +
Sbjct: 1082 SIR---DGSGLG----RFSIDDESGVITAADILDRETMGSYWLTVYATDRGVVPLYSTIE 1134

Query: 567  VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE 626
            V I V DVNDN P+  + +Y   +ME++    SV Q+ A D D   N ++ Y +      
Sbjct: 1135 VYIEVEDVNDNAPLTSEPIYYPVVMENSPKDVSVIQIQAEDPDSSSNEKLTYRI-TSGNP 1193

Query: 627  EGSFVIDPASGVI-RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685
            +  F I+  +G+I  T++ LDRE  A H L+    DGG  P+ ST+ V +++ D ND+ P
Sbjct: 1194 QNFFAINIKTGLITTTSRKLDREQQAEHFLEVTVTDGGPSPKQSTIWVVVQVLDENDNKP 1253

Query: 686  VFESDCLTFYISE--NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
             F        + E      G  I    A D DEGPNA + YSI  G+D   F ++ + G 
Sbjct: 1254 QFPEKVYQIKLPERDRKKRGEPIYRAFAFDRDEGPNAEISYSIVDGNDDGKFFIDPKTG- 1312

Query: 744  DKAELVTMVDLDYESPRKKYE-LVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQI 799
                   MV    +     Y+ L I+A     P   +  R+ I        +P+   F  
Sbjct: 1313 -------MVSSRKQFTAGSYDILTIKAVDNGRPQKSSTARLHIEWIKKPPPSPIPLTFDE 1365

Query: 800  IFNNY---KDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
             F N+   +        G V    A+    L + I+ GN  +     +  G++ ++  L+
Sbjct: 1366 PFYNFTVMESDRVTEIVGVVSVQPANT--PLWFDIVGGNFDSAFDAEKGVGTIVIAKPLD 1423

Query: 857  TNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887
                 +  M V VTDG N   A+ Q+ ++++
Sbjct: 1424 AEQRSIYNMSVEVTDGTN--VAVTQVFIKVL 1452



 Score =  310 bits (760), Expect = 5e-82
 Identities = 254/860 (29%), Positives = 400/860 (46%), Gaps = 74/860 (8%)

Query: 10   QINVLDCND--HSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
            ++ V+D N+  H+P F       SV+E +  GT+VL + A D+D G++ E++Y+I     
Sbjct: 1029 EVEVVDVNENLHTPYFPDFAVVGSVKENSRIGTSVLQVTARDEDSGRDGEIQYSI----- 1083

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
                  D               F ID  SG +     LDRE +  Y + V ATD+     
Sbjct: 1084 -----RDGSGLGR---------FSIDDESGVITAADILDRETMGSYWLTVYATDRGVV-- 1127

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
              L ST  +++ + D NDN P  SE  Y   V E+ S  D  VI +I+A D D  +N  +
Sbjct: 1128 -PLYSTIEVYIEVEDVNDNAPLTSEPIYYPVVMEN-SPKDVSVI-QIQAEDPDSSSNEKL 1184

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLV-KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
             Y I  GN Q  F+I+  +G ++   + LD EQ   + L +   DGG   + +T  +++ 
Sbjct: 1185 TYRITSGNPQNFFAINIKTGLITTTSRKLDREQQAEHFLEVTVTDGGPSPKQSTIWVVVQ 1244

Query: 247  IRDVNDNAPRFYTSLFQESVSE--NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
            + D NDN P+F   ++Q  + E      G  I R  A+D DEG NAE++Y++ D    GN
Sbjct: 1245 VLDENDNKPQFPEKVYQIKLPERDRKKRGEPIYRAFAFDRDEGPNAEISYSIVD----GN 1300

Query: 305  VDLPITIDPRSGWVYTSGQLDRETQAKYQLL-VTATDGGDPPRSATATXXXXXXXX---X 360
             D    IDP++G V +  Q    T   Y +L + A D G P +S+TA             
Sbjct: 1301 DDGKFFIDPKTGMVSSRKQF---TAGSYDILTIKAVDNGRPQKSSTARLHIEWIKKPPPS 1357

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420
                 F    Y   + E +   T +V + +     +  L ++I GGN    F   ++ G 
Sbjct: 1358 PIPLTFDEPFYNFTVMESDRV-TEIVGVVSVQ-PANTPLWFDIVGGNFDSAFD--AEKGV 1413

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
            G I +A+PLD +Q   Y ++V  TD G       V I + D N+  P F    Y  ++ E
Sbjct: 1414 GTIVIAKPLDAEQRSIYNMSVEVTD-GTNVAVTQVFIKVLDNNDNGPEFSQPNYDVTISE 1472

Query: 481  DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
            D    T +L + ATD D     +++Y++ S I + ++    ++F I+P TG + T + LD
Sbjct: 1473 DVLPDTEILQIEATDRDE--KHKLSYTVHSSIDSISM----RKFRIDPSTGVLYTAERLD 1526

Query: 541  RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
             E    ++L +  RD   P   +   V ++V D ND+ P F   LY A++ E A +G++V
Sbjct: 1527 HEAQDKHILNIMVRDQEFPYRRNLARVIVNVEDANDHSPYFTNPLYEASVFESAALGSAV 1586

Query: 601  SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
             QV A D D G N  + Y ++        F I+P  G+I   K  D  ++    L     
Sbjct: 1587 LQVTALDKDKGENAELIYTIE-AGNTGNMFKIEPVLGIITICKEPDMTTMGQFVLSIKVT 1645

Query: 661  DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
            D G+PP S+T IV I +   ++S P F        ++EN  IGT++  I A        +
Sbjct: 1646 DQGSPPMSATAIVRISVTMSDNSHPKFIHKDYQAEVNENVDIGTSVILISAIS-----QS 1700

Query: 721  VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS-PPLWNDVR 779
             + Y +K GD +  F++    G     + T   LDYE     Y+L+I+A +   + ++  
Sbjct: 1701 TLIYEVKDGDINGIFTINPYSG----VITTQKALDYER-TSSYQLIIQATNMAGMASNAT 1755

Query: 780  VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR--------VPAYDADVTDK--LQY 829
            V I + D NDNAPV   F     +  +  P+    R        + A DAD      L Y
Sbjct: 1756 VNIQIVDENDNAPVFL-FSQYSGSLSEAAPINSIVRSLDNSPLVIRATDADSNRNALLVY 1814

Query: 830  RILSGNNANLILLNETTGSM 849
            +I+         ++ +TG++
Sbjct: 1815 QIVESTAKKFFTVDSSTGAI 1834



 Score =  304 bits (746), Expect = 2e-80
 Identities = 251/844 (29%), Positives = 385/844 (45%), Gaps = 34/844 (4%)

Query: 55   NAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYT 114
            N ++     +++ +  +PE                F ID  +G L   + LD E  + Y 
Sbjct: 2197 NEDIRMNTPILSINATSPEGQGIIYIIIDGDPFKQFNIDFDTGVLKVVSPLDYEVTSAYK 2256

Query: 115  VLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKI 174
            + ++A+D  +    R   T  + VN  D NDN P F + TY  ++ E  S+   PV+ ++
Sbjct: 2257 LTIRASDALTGA--RAEVTVDLLVN--DVNDNPPIFDQPTYNTTLSE-ASLIGTPVL-QV 2310

Query: 175  KATDADVGANSAIRYAIIGG--NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232
             + DAD   N  + Y I+    N+   F IDS SG +   + LD+E V+   L +R+ D 
Sbjct: 2311 VSIDADSENNKMVHYQIVQDTYNSTDYFHIDSSSGLILTARMLDHELVQHCTLKVRSIDS 2370

Query: 233  GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292
            G PS S+   + I I DVNDN P F   +++  VSE  P G+ +  VQA DAD      L
Sbjct: 2371 GFPSLSSEVLVHIYISDVNDNPPVFNQLIYESYVSELAPRGHFVTCVQASDADSSDFDRL 2430

Query: 293  TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352
             Y++     +GN      +D +SG +  S    +  +  Y L V+ +DG     ++TA  
Sbjct: 2431 EYSIL----SGNDRTSFLMDSKSGVITLSNHRKQRMEPLYSLNVSVSDG---LFTSTAQV 2483

Query: 353  XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRG 410
                         F    Y  E+ E+   GT V+ + ATD D     ++ Y I     + 
Sbjct: 2484 HIRVLGANLYSPAFSQSTYVAEVRENVAAGTKVIHVRATDGDPGTYGQISYAIINDFAKD 2543

Query: 411  RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFE 470
            RF I S NG+ + T     +   E    + V A D GGR+    V++ + D N+ AP F 
Sbjct: 2544 RFLIDS-NGQVITTERLDRENPLEGDVSIFVRALDGGGRTTFCTVRVIVVDENDNAPQFM 2602

Query: 471  NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
               Y ASV  D   G  V  V A D D G N++ITYSL SE S  +VA       I+P  
Sbjct: 2603 TVEYRASVRADVGRGHLVTQVQAIDPDDGANSRITYSLYSEAS-VSVA---DLLEIDPDN 2658

Query: 531  GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590
            G + T    ++   +     V A DGG+P       V I V+      P F Q  Y+  I
Sbjct: 2659 GWMVTKGNFNQLKNTVLSFFVKAVDGGIPVKHSLIPVYIHVLPPETFLPSFTQSQYSFTI 2718

Query: 591  MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE-S 649
             ED  +G++V  +    +       ++ E  P++ + G FVI+  +G I+ +K LDRE S
Sbjct: 2719 AEDTAIGSTVDTLRILPSQNVWFSTVNGE-RPENNKGGIFVIEQETGTIKLDKRLDRETS 2777

Query: 650  VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
             A H   A  I         TV V IK+ D+ND+ PVFE+      I E  P+GT + ++
Sbjct: 2778 PAFHFKVAATIPLDKVDIVFTVDVDIKVLDLNDNKPVFETSSYDTIIMEGMPVGTKLTQV 2837

Query: 710  RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES-PRKKYELVIR 768
            RA D D G N  V YS+                S+   + T+ DLD+E+ P   + +V  
Sbjct: 2838 RAIDMDWGANGQVTYSLHSDSQPEKVMEAFNIDSNTGWISTLKDLDHETDPTFTFSVVAS 2897

Query: 769  --AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRV-PAYDADVTD 825
                +  L +   V + VTD+NDNAPV    ++   N K+  P G    V   +D D +D
Sbjct: 2898 DLGEAFSLSSTALVSVRVTDINDNAPVFAQ-EVYRGNVKESDPPGEVVAVLSTWDRDTSD 2956

Query: 826  ---KLQYRILSGNNANLILLN--ETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMM 880
               ++ Y I  GN      L   ++   + +   L+     +  + ++ TDG+   +AM+
Sbjct: 2957 VNRQVSYHITGGNPRGRFALGLVQSEWKVYVKRPLDREEQDIYFLNITATDGLFVTQAMV 3016

Query: 881  QLSV 884
            ++SV
Sbjct: 3017 EVSV 3020



 Score =  291 bits (714), Expect = 2e-76
 Identities = 253/861 (29%), Positives = 390/861 (45%), Gaps = 77/861 (8%)

Query: 15   DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
            D ND SP F    Y   V E    GT +  L+  D D+G   +V Y++       +N  +
Sbjct: 929  DVNDCSPAFIPSSYSVKVLEDLPVGTVIAWLETHDPDLGLGGQVRYSL-------VNDYN 981

Query: 75   AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134
                           F ID  SGA+     LD EK   Y + V+A D+  PVS  LSS +
Sbjct: 982  GR-------------FEIDKASGAIRLSKELDYEKQQFYNLTVRAKDKGRPVS--LSSVS 1026

Query: 135  TIHVNIIDDNDNY--PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192
             + V ++D N+N   P F +     SV E+  +  +  + ++ A D D G +  I+Y+I 
Sbjct: 1027 FVEVEVVDVNENLHTPYFPDFAVVGSVKENSRIGTS--VLQVTARDEDSGRDGEIQYSIR 1084

Query: 193  GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252
             G+   +FSID  SG ++    LD E + SY L + A D G     +T ++ I + DVND
Sbjct: 1085 DGSGLGRFSIDDESGVITAADILDRETMGSYWLTVYATDRGVVPLYSTIEVYIEVEDVND 1144

Query: 253  NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312
            NAP     ++   V EN P   S++++QA D D   N +LTY +T    +GN      I+
Sbjct: 1145 NAPLTSEPIYYPVVMENSPKDVSVIQIQAEDPDSSSNEKLTYRIT----SGNPQNFFAIN 1200

Query: 313  PRSGWV-YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371
             ++G +  TS +LDRE QA++ L VT TDGG  P+ +T                F    Y
Sbjct: 1201 IKTGLITTTSRKLDREQQAEHFLEVTVTDGGPSPKQSTIWVVVQVLDENDNKPQFPEKVY 1260

Query: 372  EVELAEDE--PPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
            +++L E +    G P+    A D DE  +  + Y I  GN  G+F I  + G     V+ 
Sbjct: 1261 QIKLPERDRKKRGEPIYRAFAFDRDEGPNAEISYSIVDGNDDGKFFIDPKTG----MVSS 1316

Query: 428  PLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPV---FENAPYTASVFEDA 482
               F      +LT+ A D+G   +S TA + I        +P+   F+   Y  +V E  
Sbjct: 1317 RKQFTAGSYDILTIKAVDNGRPQKSSTARLHIEWIKKPPPSPIPLTFDEPFYNFTVMESD 1376

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
             +   V VVS   +    N  + + +          + D  F      G I   K LD E
Sbjct: 1377 RVTEIVGVVSVQPA----NTPLWFDIVG-------GNFDSAFDAEKGVGTIVIAKPLDAE 1425

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
              S Y ++V   DG   ++   T V I V+D NDN P F Q  Y   I ED L  T + Q
Sbjct: 1426 QRSIYNMSVEVTDGTNVAV---TQVFIKVLDNNDNGPEFSQPNYDVTISEDVLPDTEILQ 1482

Query: 603  VGATDADV--GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
            + ATD D    L+  +H  +D     +  F IDP++GV+ T + LD E+   H L  +  
Sbjct: 1483 IEATDRDEKHKLSYTVHSSIDSISMRK--FRIDPSTGVLYTAERLDHEAQDKHILNIMVR 1540

Query: 661  DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
            D   P + +   V + +ED ND  P F +      + E++ +G+ + ++ A D D+G NA
Sbjct: 1541 DQEFPYRRNLARVIVNVEDANDHSPYFTNPLYEASVFESAALGSAVLQVTALDKDKGENA 1600

Query: 721  VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWND 777
             + Y+I+ G+  N F +E   G     ++T+      +   ++ L I+     SPP+   
Sbjct: 1601 ELIYTIEAGNTGNMFKIEPVLG-----IITICKEPDMTTMGQFVLSIKVTDQGSPPMSAT 1655

Query: 778  VRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGN 835
              V I VT  +++ P  + KD+Q   N   D   +G    V    A     L Y +  G+
Sbjct: 1656 AIVRISVTMSDNSHPKFIHKDYQAEVNENVD---IGT--SVILISAISQSTLIYEVKDGD 1710

Query: 836  NANLILLNETTGSMTLSPQLN 856
               +  +N  +G +T    L+
Sbjct: 1711 INGIFTINPYSGVITTQKALD 1731



 Score =  289 bits (708), Expect = 1e-75
 Identities = 240/854 (28%), Positives = 398/854 (46%), Gaps = 62/854 (7%)

Query: 57   EVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVL 116
            E +   E+V   ++ P +               F  +   G ++    LD E+ + Y + 
Sbjct: 1374 ESDRVTEIVGVVSVQPANTPLWFDIVGGNFDSAFDAEKGVGTIVIAKPLDAEQRSIYNMS 1433

Query: 117  VKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKA 176
            V+ TD  +       +   + + ++D+NDN P+FS+  Y V++ ED+ + D  ++ +I+A
Sbjct: 1434 VEVTDGTNV------AVTQVFIKVLDNNDNGPEFSQPNYDVTISEDV-LPDTEIL-QIEA 1485

Query: 177  TDADVGAN-SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP 235
            TD D     S   ++ I   +  +F ID  +G +   + LD+E    + L I  +D   P
Sbjct: 1486 TDRDEKHKLSYTVHSSIDSISMRKFRIDPSTGVLYTAERLDHEAQDKHILNIMVRDQEFP 1545

Query: 236  SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295
             R N  ++++N+ D ND++P F   L++ SV E+  +G ++++V A D D+G NAEL YT
Sbjct: 1546 YRRNLARVIVNVEDANDHSPYFTNPLYEASVFESAALGSAVLQVTALDKDKGENAELIYT 1605

Query: 296  MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355
            + +   TGN+     I+P  G +    + D  T  ++ L +  TD G PP SATA     
Sbjct: 1606 I-EAGNTGNM---FKIEPVLGIITICKEPDMTTMGQFVLSIKVTDQGSPPMSATAIVRIS 1661

Query: 356  XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSIT 415
                      F+   Y+ E+ E+   GT V+ ++A      + L YE+  G+  G F+I 
Sbjct: 1662 VTMSDNSHPKFIHKDYQAEVNENVDIGTSVILISAI---SQSTLIYEVKDGDINGIFTIN 1718

Query: 416  SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYT 475
              +  G+IT  + LD+++   Y L + AT+  G +  A V I I D N+ APVF  + Y+
Sbjct: 1719 PYS--GVITTQKALDYERTSSYQLIIQATNMAGMASNATVNIQIVDENDNAPVFLFSQYS 1776

Query: 476  ASVFEDAPIGTTV-------LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528
             S+ E API + V       LV+ ATD+D   NA + Y +    + +        F ++ 
Sbjct: 1777 GSLSEAAPINSIVRSLDNSPLVIRATDADSNRNALLVYQIVESTAKKF-------FTVDS 1829

Query: 529  QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE--ISVVDVNDNEPVFKQQLY 586
             TGAI T   LD ET++ +   V  RD G P L+  + VE  I V DVNDN PVF Q ++
Sbjct: 1830 STGAIRTIANLDHETIAHFHFHVHVRDSGSPQLTAESPVEVNIEVTDVNDNPPVFTQAVF 1889

Query: 587  TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR-TNKAL 645
               ++    VG  V +V ATD D  +   + Y L   +     F+ID  SGV+   N  L
Sbjct: 1890 ETILLLPTYVGVEVLKVSATDPDSEVPPELTYSL--MEGSLDHFLIDSNSGVLTIKNNNL 1947

Query: 646  DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
             ++    H +  V +  G     ST +V I +++  DS   F     +  ISEN+   T 
Sbjct: 1948 SKD----HYMLIVKVSDG--KFYSTSMVTIMVKEAMDSGLHFTQSFYSTSISENNTNITK 2001

Query: 706  IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765
            +  + A       N  + YSI   +  N F +++  G  +    T V  D E  ++ YEL
Sbjct: 2002 VAIVNA--VGNRLNEPLKYSIL--NPGNKFKIKSTSGVIQ---TTGVPFDREE-QELYEL 2053

Query: 766  VIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD 822
            V+ A+          V V + + D+NDN+PV            D  P     +V A D D
Sbjct: 2054 VVEASRELDHLRVARVVVRVNIEDINDNSPVFVGLPYYAAVQVDAEPGTLIYQVTAIDKD 2113

Query: 823  VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVT-----DGVNEIK 877
                 +   +  ++     +N  +G++ L    N++   L+ +E  VT      G   + 
Sbjct: 2114 KGPNGEVTYVLQDDYGHFEINPNSGNVILKEAFNSD---LSNIEYGVTILAKDGGKPSLS 2170

Query: 878  AMMQLSVRLITEEM 891
              ++L + ++ + M
Sbjct: 2171 TSVELPITIVNKAM 2184



 Score =  288 bits (706), Expect = 2e-75
 Identities = 254/878 (28%), Positives = 394/878 (44%), Gaps = 68/878 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            INV D ND+SPVF    Y  ++ E +  GT ++ ++A D+D+G N EV Y+   V  DT 
Sbjct: 820  INVEDANDNSPVFIQDSYSVNILESSGIGTEIIQVEARDKDLGSNGEVTYS---VLTDT- 875

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F I+  +G +     LDRE  A Y++ ++A D+A     +L
Sbjct: 876  -----------------QQFAINSSTGIVYVADQLDRESKANYSLKIEARDKAES-GQQL 917

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             S  T+ V + D ND  P F   +Y+V V ED+ V    VIA ++  D D+G    +RY+
Sbjct: 918  FSVVTLKVFLDDVNDCSPAFIPSSYSVKVLEDLPV--GTVIAWLETHDPDLGLGGQVRYS 975

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP-SRSNTTQLLINIRD 249
            ++  +   +F ID  SG + L K LDYE+ + Y L +RA+D G P S S+ + + + + D
Sbjct: 976  LV-NDYNGRFEIDKASGAIRLSKELDYEKQQFYNLTVRAKDKGRPVSLSSVSFVEVEVVD 1034

Query: 250  VNDN--APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            VN+N   P F       SV EN  IG S+++V A D D G + E+ Y++ D    G    
Sbjct: 1035 VNENLHTPYFPDFAVVGSVKENSRIGTSVLQVTARDEDSGRDGEIQYSIRDGSGLGR--- 1091

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
              +ID  SG +  +  LDRET   Y L V ATD G  P  +T                  
Sbjct: 1092 -FSIDDESGVITAADILDRETMGSYWLTVYATDRGVVPLYSTIEVYIEVEDVNDNAPLTS 1150

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITV 425
               Y   + E+ P    V+ + A D D   + +L Y IT GN +  F+I  + G  + T 
Sbjct: 1151 EPIYYPVVMENSPKDVSVIQIQAEDPDSSSNEKLTYRITSGNPQNFFAINIKTGL-ITTT 1209

Query: 426  AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFE--D 481
            ++ LD +Q+  + L V+ TD G   +  T  V + + D N+  P F    Y   + E   
Sbjct: 1210 SRKLDREQQAEHFLEVTVTDGGPSPKQSTIWVVVQVLDENDNKPQFPEKVYQIKLPERDR 1269

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
               G  +    A D D G NA+I+YS+          + D +F I+P+TG +++ K   +
Sbjct: 1270 KKRGEPIYRAFAFDRDEGPNAEISYSIVD-------GNDDGKFFIDPKTGMVSSRK---Q 1319

Query: 542  ETMSGY-LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV---FKQQLYTANIMEDALVG 597
             T   Y +LT+ A D G P  S T  + I  +      P+   F +  Y   +ME   V 
Sbjct: 1320 FTAGSYDILTIKAVDNGRPQKSSTARLHIEWIKKPPPSPIPLTFDEPFYNFTVMESDRVT 1379

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
              V  V    A    N  + +++      + +F  +   G I   K LD E  + +++  
Sbjct: 1380 EIVGVVSVQPA----NTPLWFDI-VGGNFDSAFDAEKGVGTIVIAKPLDAEQRSIYNMSV 1434

Query: 658  VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
               DG      +   V IK+ D ND+ P F        ISE+    T I +I A D DE 
Sbjct: 1435 EVTDG---TNVAVTQVFIKVLDNNDNGPEFSQPNYDVTISEDVLPDTEILQIEATDRDE- 1490

Query: 718  PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK-YELVIRAAS-PPLW 775
                + Y++    DS S   + R       L T   LD+E+  K    +++R    P   
Sbjct: 1491 -KHKLSYTVHSSIDSISMR-KFRIDPSTGVLYTAERLDHEAQDKHILNIMVRDQEFPYRR 1548

Query: 776  NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILS 833
            N  RV + V D ND++P   +     + ++         +V A D D  +  +L Y I +
Sbjct: 1549 NLARVIVNVEDANDHSPYFTNPLYEASVFESAALGSAVLQVTALDKDKGENAELIYTIEA 1608

Query: 834  GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            GN  N+  +    G +T+  + +        + + VTD
Sbjct: 1609 GNTGNMFKIEPVLGIITICKEPDMTTMGQFVLSIKVTD 1646



 Score =  287 bits (704), Expect = 3e-75
 Identities = 249/877 (28%), Positives = 396/877 (45%), Gaps = 77/877 (8%)

Query: 17   NDHSPVFEMQ-QYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDA 75
            N   P F+     + +V+E    G  +L +KA D D G N +V +TI     D+      
Sbjct: 720  NRQGPYFDKSFPSDVAVKEDLPVGANILKIKAYDADSGFNGKVLFTISDGNTDSC----- 774

Query: 76   XXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTAT 135
                          F ID  +G L     +DRE    Y + +   D  +P   + SS   
Sbjct: 775  --------------FNIDMETGQLKVLMPMDREHTDLYLLNITIYDLGNP---QKSSWRL 817

Query: 136  IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195
            + +N+ D NDN P F + +Y+V++ E   +     I +++A D D+G+N  + Y+++  +
Sbjct: 818  LTINVEDANDNSPVFIQDSYSVNILESSGI--GTEIIQVEARDKDLGSNGEVTYSVL-TD 874

Query: 196  TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS--NTTQLLINIRDVNDN 253
            TQ QF+I+S +G V +   LD E   +Y L I A+D     +   +   L + + DVND 
Sbjct: 875  TQ-QFAINSSTGIVYVADQLDRESKANYSLKIEARDKAESGQQLFSVVTLKVFLDDVNDC 933

Query: 254  APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313
            +P F  S +   V E++P+G  I  ++ +D D G+  ++ Y++ + DY G  +    ID 
Sbjct: 934  SPAFIPSSYSVKVLEDLPVGTVIAWLETHDPDLGLGGQVRYSLVN-DYNGRFE----IDK 988

Query: 314  RSGWVYTSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXXXXFMPGQY 371
             SG +  S +LD E Q  Y L V A D G P    S +                + P   
Sbjct: 989  ASGAIRLSKELDYEKQQFYNLTVRAKDKGRPVSLSSVSFVEVEVVDVNENLHTPYFPDFA 1048

Query: 372  EV-ELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
             V  + E+   GT V+ +TA D D   D  + Y I  G+  GRFSI  ++  G+IT A  
Sbjct: 1049 VVGSVKENSRIGTSVLQVTARDEDSGRDGEIQYSIRDGSGLGRFSIDDES--GVITAADI 1106

Query: 429  LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
            LD +    Y LTV ATD G      T  V I + D N+ AP+     Y   V E++P   
Sbjct: 1107 LDRETMGSYWLTVYATDRGVVPLYSTIEVYIEVEDVNDNAPLTSEPIYYPVVMENSPKDV 1166

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKLLDRETMS 545
            +V+ + A D D   N ++TY ++S        +    F IN +TG I TT++ LDRE  +
Sbjct: 1167 SVIQIQAEDPDSSSNEKLTYRITS-------GNPQNFFAINIKTGLITTTSRKLDREQQA 1219

Query: 546  GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME--DALVGTSVSQV 603
             + L VT  DGG      T  V + V+D NDN+P F +++Y   + E      G  + + 
Sbjct: 1220 EHFLEVTVTDGGPSPKQSTIWVVVQVLDENDNKPQFPEKVYQIKLPERDRKKRGEPIYRA 1279

Query: 604  GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV-AIDG 662
             A D D G N  I Y +     ++G F IDP +G++ + K     +  ++D+  + A+D 
Sbjct: 1280 FAFDRDEGPNAEISYSI-VDGNDDGKFFIDPKTGMVSSRKQF---TAGSYDILTIKAVDN 1335

Query: 663  GTPPQSSTVIVHIKIEDINDSPP-----VFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
            G P +SST  +H  IE I   PP      F+     F + E+  +   +G +      + 
Sbjct: 1336 GRPQKSSTARLH--IEWIKKPPPSPIPLTFDEPFYNFTVMESDRVTEIVGVVSV----QP 1389

Query: 718  PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND 777
             N  + + I GG+  ++F  E   G+    +V    LD E  R  Y + +          
Sbjct: 1390 ANTPLWFDIVGGNFDSAFDAEKGVGT----IVIAKPLDAEQ-RSIYNMSVEVTDGTNVAV 1444

Query: 778  VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNA 837
             +V I V D NDN P            +D  P     ++ A D D   KL Y + S  ++
Sbjct: 1445 TQVFIKVLDNNDNGPEFSQPNYDVTISEDVLPDTEILQIEATDRDEKHKLSYTVHSSIDS 1504

Query: 838  ---NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
                   ++ +TG +  + +L+        + + V D
Sbjct: 1505 ISMRKFRIDPSTGVLYTAERLDHEAQDKHILNIMVRD 1541



 Score =  280 bits (686), Expect = 5e-73
 Identities = 266/902 (29%), Positives = 415/902 (46%), Gaps = 83/902 (9%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            I   I V D ND++P+     Y   V E +    +V+ ++A D D   N ++ Y I    
Sbjct: 1133 IEVYIEVEDVNDNAPLTSEPIYYPVVMENSPKDVSVIQIQAEDPDSSSNEKLTYRIT--- 1189

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRA-SLDREKVARYTVLVKATDQASP 125
              + NP              Q+ F I+ ++G + T +  LDRE+ A + + V  TD   P
Sbjct: 1190 --SGNP--------------QNFFAINIKTGLITTTSRKLDREQQAEHFLEVTVTD-GGP 1232

Query: 126  VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
               +  ST  + V ++D+NDN PQF EK Y + + E         I +  A D D G N+
Sbjct: 1233 SPKQ--STIWVVVQVLDENDNKPQFPEKVYQIKLPERDRKKRGEPIYRAFAFDRDEGPNA 1290

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR-LVIRAQDGGSPSRSNTTQLL 244
             I Y+I+ GN   +F ID  +G VS  K        SY  L I+A D G P +S+T +L 
Sbjct: 1291 EISYSIVDGNDDGKFFIDPKTGMVSSRKQF---TAGSYDILTIKAVDNGRPQKSSTARL- 1346

Query: 245  INIRDVNDNAPRFYTSLFQES-VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
             +I  +    P      F E   +  V     +  +    + +  N  L + +      G
Sbjct: 1347 -HIEWIKKPPPSPIPLTFDEPFYNFTVMESDRVTEIVGVVSVQPANTPLWFDIVG----G 1401

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
            N D     +   G +  +  LD E ++ Y + V  TDG      A               
Sbjct: 1402 NFDSAFDAEKGVGTIVIAKPLDAEQRSIYNMSVEVTDG---TNVAVTQVFIKVLDNNDNG 1458

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG-NTRGRFSITSQNGRGL 422
              F    Y+V ++ED  P T ++ + ATD DE ++L Y +    ++            G+
Sbjct: 1459 PEFSQPNYDVTISEDVLPDTEILQIEATDRDEKHKLSYTVHSSIDSISMRKFRIDPSTGV 1518

Query: 423  ITVAQPLDFKQERRYVLTVSATDS--GGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
            +  A+ LD + + +++L +   D     R + A V +N+ DAN+++P F N  Y ASVFE
Sbjct: 1519 LYTAERLDHEAQDKHILNIMVRDQEFPYRRNLARVIVNVEDANDHSPYFTNPLYEASVFE 1578

Query: 481  DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
             A +G+ VL V+A D D G NA++ Y++  E  N         F I P  G IT  K  D
Sbjct: 1579 SAALGSAVLQVTALDKDKGENAELIYTI--EAGNTG-----NMFKIEPVLGIITICKEPD 1631

Query: 541  RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
              TM  ++L++   D G P +S T  V ISV   +++ P F  + Y A + E+  +GTSV
Sbjct: 1632 MTTMGQFVLSIKVTDQGSPPMSATAIVRISVTMSDNSHPKFIHKDYQAEVNENVDIGTSV 1691

Query: 601  SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
              + A          + YE+   D   G F I+P SGVI T KALD E  +++ L   A 
Sbjct: 1692 ILISAIS-----QSTLIYEVKDGD-INGIFTINPYSGVITTQKALDYERTSSYQLIIQAT 1745

Query: 661  DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE-------IRAHD 713
            +      +S   V+I+I D ND+ PVF     +  +SE +PI + +         IRA D
Sbjct: 1746 N--MAGMASNATVNIQIVDENDNAPVFLFSQYSGSLSEAAPINSIVRSLDNSPLVIRATD 1803

Query: 714  PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES-PRKKYELVIR-AAS 771
             D   NA++ Y I        F++++  G+    + T+ +LD+E+     + + +R + S
Sbjct: 1804 ADSNRNALLVYQIVESTAKKFFTVDSSTGA----IRTIANLDHETIAHFHFHVHVRDSGS 1859

Query: 772  PPLW--NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP--VG-PFGRVPAYDAD--VT 824
            P L   + V V I VTDVNDN PV    Q +F       P  VG    +V A D D  V 
Sbjct: 1860 PQLTAESPVEVNIEVTDVNDNPPVFT--QAVFETIL-LLPTYVGVEVLKVSATDPDSEVP 1916

Query: 825  DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATM-EVSVTDGVNEIKAMMQLS 883
             +L Y ++ G + +  L++  +G +T+    N N+ K   M  V V+DG     +M+ + 
Sbjct: 1917 PELTYSLMEG-SLDHFLIDSNSGVLTIK---NNNLSKDHYMLIVKVSDGKFYSTSMVTIM 1972

Query: 884  VR 885
            V+
Sbjct: 1973 VK 1974



 Score =  277 bits (680), Expect = 2e-72
 Identities = 247/797 (30%), Positives = 370/797 (46%), Gaps = 63/797 (7%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++N+ D ND+SPVF    Y A+V+  A  GT +  + A D+D G N EV Y ++      
Sbjct: 2072 RVNIEDINDNSPVFVGLPYYAAVQVDAEPGTLIYQVTAIDKDKGPNGEVTYVLQ------ 2125

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDRE-KVARYTVLVKATDQASPVSD 128
               +D               F I+  SG ++ + + + +     Y V + A D   P   
Sbjct: 2126 ---DDYGH------------FEINPNSGNVILKEAFNSDLSNIEYGVTILAKDGGKP--- 2167

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             LS++  + + I+  N   P F +  YT SV+EDI +  N  I  I AT  +      I 
Sbjct: 2168 SLSTSVELPITIV--NKAMPVFDKPFYTASVNEDIRM--NTPILSINATSPE---GQGII 2220

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN-TTQLLINI 247
            Y II G+   QF+ID  +G + +V  LDYE   +Y+L IRA D  + +R+  T  LL+N 
Sbjct: 2221 YIIIDGDPFKQFNIDFDTGVLKVVSPLDYEVTSAYKLTIRASDALTGARAEVTVDLLVN- 2279

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
             DVNDN P F    +  ++SE   IG  +++V + DAD   N  + Y +    Y  + D 
Sbjct: 2280 -DVNDNPPIFDQPTYNTTLSEASLIGTPVLQVVSIDADSENNKMVHYQIVQDTY-NSTDY 2337

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
               ID  SG + T+  LD E      L V + D G P  S+                 F 
Sbjct: 2338 -FHIDSSSGLILTARMLDHELVQHCTLKVRSIDSGFPSLSSEVLVHIYISDVNDNPPVFN 2396

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITV 425
               YE  ++E  P G  V  + A+DAD    +RL Y I  GN R  F + S++  G+IT+
Sbjct: 2397 QLIYESYVSELAPRGHFVTCVQASDADSSDFDRLEYSILSGNDRTSFLMDSKS--GVITL 2454

Query: 426  AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
            +     + E  Y L VS +D G  + TA V I +  AN Y+P F  + Y A V E+   G
Sbjct: 2455 SNHRKQRMEPLYSLNVSVSD-GLFTSTAQVHIRVLGANLYSPAFSQSTYVAEVRENVAAG 2513

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET-M 544
            T V+ V ATD D G   QI+Y++ ++ + +       +F+I+   G + T + LDRE  +
Sbjct: 2514 TKVIHVRATDGDPGTYGQISYAIINDFAKD-------RFLID-SNGQVITTERLDRENPL 2565

Query: 545  SGYL-LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
             G + + V A DGG  +   T  V + VVD NDN P F    Y A++  D   G  V+QV
Sbjct: 2566 EGDVSIFVRALDGGGRTTFCT--VRVIVVDENDNAPQFMTVEYRASVRADVGRGHLVTQV 2623

Query: 604  GATDADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
             A D D G N RI Y L  +          IDP +G + T    ++           A+D
Sbjct: 2624 QAIDPDDGANSRITYSLYSEASVSVADLLEIDPDNGWMVTKGNFNQLKNTVLSFFVKAVD 2683

Query: 662  GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
            GG P + S + V+I +       P F     +F I+E++ IG+T+  +R         + 
Sbjct: 2684 GGIPVKHSLIPVYIHVLPPETFLPSFTQSQYSFTIAEDTAIGSTVDTLRILPSQNVWFST 2743

Query: 722  VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPRKKYEL--VIRAASPPLWNDV 778
            V+      +    F +E   G+ K +      LD E SP   +++   I      +   V
Sbjct: 2744 VNGERPENNKGGIFVIEQETGTIKLD----KRLDRETSPAFHFKVAATIPLDKVDIVFTV 2799

Query: 779  RVEILVTDVNDNAPVMK 795
             V+I V D+NDN PV +
Sbjct: 2800 DVDIKVLDLNDNKPVFE 2816



 Score =  276 bits (677), Expect = 6e-72
 Identities = 237/792 (29%), Positives = 360/792 (45%), Gaps = 64/792 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTV-------LTLKATDQDIGKNAEVEYTIE 63
            I ++D ND++PVF   QY  S+ E A   + V       L ++ATD D  +NA + Y I 
Sbjct: 1758 IQIVDENDNAPVFLFSQYSGSLSEAAPINSIVRSLDNSPLVIRATDADSNRNALLVYQIV 1817

Query: 64   LVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQA 123
              TA                   +  F +D  +GA+ T A+LD E +A +   V   D  
Sbjct: 1818 ESTA-------------------KKFFTVDSSTGAIRTIANLDHETIAHFHFHVHVRDSG 1858

Query: 124  SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183
            SP      S   +++ + D NDN P F++  +   +     V     + K+ ATD D   
Sbjct: 1859 SPQLTA-ESPVEVNIEVTDVNDNPPVFTQAVFETILLLPTYV--GVEVLKVSATDPDSEV 1915

Query: 184  NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
               + Y+++ G+    F IDS SG V  +K  +  +   Y L+++  DG   S S  T  
Sbjct: 1916 PPELTYSLMEGSLD-HFLIDSNSG-VLTIKNNNLSKDH-YMLIVKVSDGKFYSTSMVT-- 1970

Query: 244  LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA-DEGVNAELTYTMTDKDYT 302
             I +++  D+   F  S +  S+SEN     +I +V   +A    +N  L Y++ +    
Sbjct: 1971 -IMVKEAMDSGLHFTQSFYSTSISEN---NTNITKVAIVNAVGNRLNEPLKYSILNP--- 2023

Query: 303  GNVDLPITIDPRSGWVYTSG-QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
            GN      I   SG + T+G   DRE Q  Y+L+V A+   D  R A             
Sbjct: 2024 GN---KFKIKSTSGVIQTTGVPFDREEQELYELVVEASRELDHLRVARVVVRVNIEDIND 2080

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421
                F+   Y   +  D  PGT +  +TA D D+           +  G F I   +G  
Sbjct: 2081 NSPVFVGLPYYAAVQVDAEPGTLIYQVTAIDKDKGPNGEVTYVLQDDYGHFEINPNSGNV 2140

Query: 422  LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
            ++  A   D      Y +T+ A D G  S +  V++ IT  N   PVF+   YTASV ED
Sbjct: 2141 ILKEAFNSDLSNIE-YGVTILAKDGGKPSLSTSVELPITIVNKAMPVFDKPFYTASVNED 2199

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
              + T +L ++AT  +      I Y +   I  +      +QF I+  TG +     LD 
Sbjct: 2200 IRMNTPILSINATSPE---GQGIIYII---IDGDPF----KQFNIDFDTGVLKVVSPLDY 2249

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
            E  S Y LT+ A D    + ++ T V++ V DVNDN P+F Q  Y   + E +L+GT V 
Sbjct: 2250 EVTSAYKLTIRASDALTGARAEVT-VDLLVNDVNDNPPIFDQPTYNTTLSEASLIGTPVL 2308

Query: 602  QVGATDADVGLNGRIHYEL-DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
            QV + DAD   N  +HY++          F ID +SG+I T + LD E V    LK  +I
Sbjct: 2309 QVVSIDADSENNKMVHYQIVQDTYNSTDYFHIDSSSGLILTARMLDHELVQHCTLKVRSI 2368

Query: 661  DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
            D G P  SS V+VHI I D+ND+PPVF       Y+SE +P G  +  ++A D D     
Sbjct: 2369 DSGFPSLSSEVLVHIYISDVNDNPPVFNQLIYESYVSELAPRGHFVTCVQASDADSSDFD 2428

Query: 721  VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRV 780
             + YSI  G+D  SF ++++ G     ++T+ +   +     Y L +  +     +  +V
Sbjct: 2429 RLEYSILSGNDRTSFLMDSKSG-----VITLSNHRKQRMEPLYSLNVSVSDGLFTSTAQV 2483

Query: 781  EILVTDVNDNAP 792
             I V   N  +P
Sbjct: 2484 HIRVLGANLYSP 2495



 Score =  248 bits (608), Expect = 1e-63
 Identities = 167/518 (32%), Positives = 267/518 (51%), Gaps = 37/518 (7%)

Query: 372  EVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
            +V + ED P G  ++ + A DAD   + ++ + I+ GNT   F+I  + G+  + V  P+
Sbjct: 733  DVAVKEDLPVGANILKIKAYDADSGFNGKVLFTISDGNTDSCFNIDMETGQ--LKVLMPM 790

Query: 430  DFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
            D +    Y+L ++  D G   +S   ++ IN+ DAN+ +PVF    Y+ ++ E + IGT 
Sbjct: 791  DREHTDLYLLNITIYDLGNPQKSSWRLLTINVEDANDNSPVFIQDSYSVNILESSGIGTE 850

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
            ++ V A D D+G N ++TYS+ ++          QQF IN  TG +     LDRE+ + Y
Sbjct: 851  IIQVEARDKDLGSNGEVTYSVLTD---------TQQFAINSSTGIVYVADQLDRESKANY 901

Query: 548  LLTVTARDGGV--PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
             L + ARD       L     +++ + DVND  P F    Y+  ++ED  VGT ++ +  
Sbjct: 902  SLKIEARDKAESGQQLFSVVTLKVFLDDVNDCSPAFIPSSYSVKVLEDLPVGTVIAWLET 961

Query: 606  TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
             D D+GL G++ Y L   +   G F ID ASG IR +K LD E    ++L   A D G P
Sbjct: 962  HDPDLGLGGQVRYSL--VNDYNGRFEIDKASGAIRLSKELDYEKQQFYNLTVRAKDKGRP 1019

Query: 666  PQSSTV-IVHIKIEDINDS--PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
               S+V  V +++ D+N++   P F    +   + ENS IGT++ ++ A D D G +  +
Sbjct: 1020 VSLSSVSFVEVEVVDVNENLHTPYFPDFAVVGSVKENSRIGTSVLQVTARDEDSGRDGEI 1079

Query: 723  HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVR 779
             YSI+ G     FS++     D++ ++T  D+        Y L + A      PL++ + 
Sbjct: 1080 QYSIRDGSGLGRFSID-----DESGVITAADILDRETMGSYWLTVYATDRGVVPLYSTIE 1134

Query: 780  VEILVTDVNDNAPVMKD---FQIIF-NNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGN 835
            V I V DVNDNAP+  +   + ++  N+ KD   +      P  D+   +KL YRI SGN
Sbjct: 1135 VYIEVEDVNDNAPLTSEPIYYPVVMENSPKDVSVIQIQAEDP--DSSSNEKLTYRITSGN 1192

Query: 836  NANLILLNETTGSM-TLSPQLNTNVPKLATMEVSVTDG 872
              N   +N  TG + T S +L+        +EV+VTDG
Sbjct: 1193 PQNFFAINIKTGLITTTSRKLDREQQAEHFLEVTVTDG 1230



 Score =  191 bits (466), Expect = 2e-46
 Identities = 174/594 (29%), Positives = 277/594 (46%), Gaps = 51/594 (8%)

Query: 103 ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162
           A L+RE    Y ++VK + +     + L +   +++ ++D ND  P FS  TY+V++ E 
Sbjct: 116 AILNREIQDNYLLIVKGSVRG----EDLEAWTKVNIQVLDMNDLRPLFSPTTYSVTIAES 171

Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222
             +  +  +A++ ATDAD+G+N    Y     N    FS+   SG +SL   L+Y++   
Sbjct: 172 TPLRTS--VAQVTATDADIGSNGEFYYYF--KNKVDLFSVHPTSGVISLSGRLNYDEKNR 227

Query: 223 YRLVIRAQDG-----GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277
           Y L I A D      G+   S+T +L ++I  +N++AP  +         E  P  Y++V
Sbjct: 228 YDLEILAVDRGMKLYGNNGVSSTAKLYVHIERINEHAPTIHVVTHVPFSLEKEPT-YAVV 286

Query: 278 RVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW-----VYTSGQLDRET-QAK 331
            V   D D+G N E+          G+      +     W     +    Q+D E+    
Sbjct: 287 TVD--DLDDGANGEIESVSI---VAGDPLDQFFLAKEGKWLNEYKIKERKQIDWESFPYG 341

Query: 332 YQLLVTATDGGDPPR-SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTA 390
           Y L + A D G P + SA                 F    Y+V ++E  PPG  V  +  
Sbjct: 342 YNLTLQAKDKGSPQKCSALKAVYIGNPTRDTVPIRFEKEVYDVSISEFSPPGVVVAIVKL 401

Query: 391 TDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS 450
           +    D  + Y+++ G     F I  ++  GLI  A+PL+  ++  Y L V+  +   + 
Sbjct: 402 SPEPID--VEYKLSPGEDAVYFKINPRS--GLIVTARPLNTVKKEVYKLEVTNKEGDLK- 456

Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510
             A V I+I DAN++ P F+   Y A V E  P+GT+VL VSA+D D G N  ITYS++S
Sbjct: 457 --AQVTISIEDANDHTPEFQQPLYDAYVNESVPVGTSVLTVSASDKDKGENGYITYSIAS 514

Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG-YLLTVTARDGGVPSLSDT-TDVE 568
                    +   FVIN  TG I+T + LD E+    Y   V A D G P   ++  +V 
Sbjct: 515 --------LNLLPFVINQFTGVISTTEELDFESSPEIYRFIVRASDWGSPYRHESEVNVT 566

Query: 569 ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG 628
           I + +VNDN P+F++      I  D  VG  ++ V A D D      + Y++     E G
Sbjct: 567 IRIGNVNDNSPLFEKVACQGVISYDFPVGGHITAVSAIDIDE--LELVKYKI-ISGNELG 623

Query: 629 SFVIDPASGVIRTNKALDRESVATHD--LKAVAIDG---GTPPQSSTVIVHIKI 677
            F ++P SGV++  K+L    +   +  L+  A DG     P   +  ++H K+
Sbjct: 624 FFYLNPDSGVLQLKKSLTNSGIKNGNFALRITATDGENLADPMSINISVLHGKV 677



 Score =  182 bits (442), Expect = 2e-43
 Identities = 132/437 (30%), Positives = 215/437 (49%), Gaps = 30/437 (6%)

Query: 463  NNYAPVFENA-PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521
            N   P F+ + P   +V ED P+G  +L + A D+D G N ++ +++S         + D
Sbjct: 720  NRQGPYFDKSFPSDVAVKEDLPVGANILKIKAYDADSGFNGKVLFTISD-------GNTD 772

Query: 522  QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581
              F I+ +TG +     +DRE    YLL +T  D G P  S    + I+V D NDN PVF
Sbjct: 773  SCFNIDMETGQLKVLMPMDREHTDLYLLNITIYDLGNPQKSSWRLLTINVEDANDNSPVF 832

Query: 582  KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641
             Q  Y+ NI+E + +GT + QV A D D+G NG + Y +    ++   F I+ ++G++  
Sbjct: 833  IQDSYSVNILESSGIGTEIIQVEARDKDLGSNGEVTYSVLTDTQQ---FAINSSTGIVYV 889

Query: 642  NKALDRESVATHDLKAVAIDGGTPPQS--STVIVHIKIEDINDSPPVFESDCLTFYISEN 699
               LDRES A + LK  A D     Q   S V + + ++D+ND  P F     +  + E+
Sbjct: 890  ADQLDRESKANYSLKIEARDKAESGQQLFSVVTLKVFLDDVNDCSPAFIPSSYSVKVLED 949

Query: 700  SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759
             P+GT I  +  HDPD G    V YS+   D +  F ++   G+ +       +LDYE  
Sbjct: 950  LPVGTVIAWLETHDPDLGLGGQVRYSLV-NDYNGRFEIDKASGAIRLS----KELDYEK- 1003

Query: 760  RKKYELVIRA---ASPPLWNDVR-VEILVTDVNDN--APVMKDFQIIFNNYKDCFPVG-P 812
            ++ Y L +RA     P   + V  VE+ V DVN+N   P   DF ++  + K+   +G  
Sbjct: 1004 QQFYNLTVRAKDKGRPVSLSSVSFVEVEVVDVNENLHTPYFPDFAVV-GSVKENSRIGTS 1062

Query: 813  FGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVT 870
              +V A D D     ++QY I  G+      +++ +G +T +  L+        + V  T
Sbjct: 1063 VLQVTARDEDSGRDGEIQYSIRDGSGLGRFSIDDESGVITAADILDRETMGSYWLTVYAT 1122

Query: 871  D-GVNEIKAMMQLSVRL 886
            D GV  + + +++ + +
Sbjct: 1123 DRGVVPLYSTIEVYIEV 1139



 Score =  163 bits (395), Expect = 8e-38
 Identities = 164/599 (27%), Positives = 263/599 (43%), Gaps = 48/599 (8%)

Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380
           S  L+RE Q  Y L+V  +  G+   + T                F P  Y V +AE  P
Sbjct: 115 SAILNREIQDNYLLIVKGSVRGEDLEAWTKVNIQVLDMNDLRPL-FSPTTYSVTIAESTP 173

Query: 381 PGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440
             T V  +TATDAD  +   +     N    FS+   +G  +I+++  L++ ++ RY L 
Sbjct: 174 LRTSVAQVTATDADIGSNGEFYYYFKNKVDLFSVHPTSG--VISLSGRLNYDEKNRYDLE 231

Query: 441 VSATDSG-------GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
           + A D G       G S TA + ++I   N +AP      +     E  P   T  VV+ 
Sbjct: 232 ILAVDRGMKLYGNNGVSSTAKLYVHIERINEHAPTIHVVTHVPFSLEKEP---TYAVVTV 288

Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP----QTGAITTNKLLDRETMS-GYL 548
            D D G N +I       +S  A    DQ F+           I   K +D E+   GY 
Sbjct: 289 DDLDDGANGEI-----ESVSIVAGDPLDQFFLAKEGKWLNEYKIKERKQIDWESFPYGYN 343

Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPV-FKQQLYTANIMEDALVGTSVSQVGATD 607
           LT+ A+D G P                D  P+ F++++Y  +I E +  G  V+ V  + 
Sbjct: 344 LTLQAKDKGSPQKCSALKAVYIGNPTRDTVPIRFEKEVYDVSISEFSPPGVVVAIVKLSP 403

Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
             +     + Y+L P + +   F I+P SG+I T + L+      + L+    +G    Q
Sbjct: 404 EPID----VEYKLSPGE-DAVYFKINPRSGLIVTARPLNTVKKEVYKLEVTNKEGDLKAQ 458

Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
                V I IED ND  P F+      Y++E+ P+GT++  + A D D+G N  + YSI 
Sbjct: 459 -----VTISIEDANDHTPEFQQPLYDAYVNESVPVGTSVLTVSASDKDKGENGYITYSIA 513

Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLW-NDVRVEIL 783
                N       Q +    + T  +LD+ES  + Y  ++RA+   SP    ++V V I 
Sbjct: 514 ---SLNLLPFVINQFT--GVISTTEELDFESSPEIYRFIVRASDWGSPYRHESEVNVTIR 568

Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPAYDADVTDKLQYRILSGNNANLILL 842
           + +VNDN+P+ +          D FPV G    V A D D  + ++Y+I+SGN      L
Sbjct: 569 IGNVNDNSPLFEKVACQGVISYD-FPVGGHITAVSAIDIDELELVKYKIISGNELGFFYL 627

Query: 843 NETTGSMTLSPQLNTNVPKLA--TMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVR 899
           N  +G + L   L  +  K     + ++ TDG N +   M +++ ++  ++   S + R
Sbjct: 628 NPDSGVLQLKKSLTNSGIKNGNFALRITATDGEN-LADPMSINISVLHGKVSSKSFSCR 685



 Score =  131 bits (317), Expect = 2e-28
 Identities = 150/580 (25%), Positives = 245/580 (42%), Gaps = 71/580 (12%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I VLD ND  P+F    Y  ++ E     T+V  + ATD DIG N E  Y  +       
Sbjct: 147 IQVLDMNDLRPLFSPTTYSVTIAESTPLRTSVAQVTATDADIGSNGEFYYYFKNKV---- 202

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV--SD 128
                            D+F +   SG +     L+ ++  RY + + A D+   +  ++
Sbjct: 203 -----------------DLFSVHPTSGVISLSGRLNYDEKNRYDLEILAVDRGMKLYGNN 245

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            +SSTA ++V+I   N++ P     T  V      S+   P  A +   D D GAN  I 
Sbjct: 246 GVSSTAKLYVHIERINEHAP-----TIHVVTHVPFSLEKEPTYAVVTVDDLDDGANGEIE 300

Query: 189 -YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV------RSYRLVIRAQDGGSPSRSNTT 241
             +I+ G+   QF +      ++  K  + +Q+        Y L ++A+D GSP + +  
Sbjct: 301 SVSIVAGDPLDQFFLAKEGKWLNEYKIKERKQIDWESFPYGYNLTLQAKDKGSPQKCSAL 360

Query: 242 QLLINIRDVNDNAP-RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
           + +       D  P RF   ++  S+SE  P G  +  V+   + E ++ E  Y ++   
Sbjct: 361 KAVYIGNPTRDTVPIRFEKEVYDVSISEFSPPGVVVAIVKL--SPEPIDVE--YKLS--- 413

Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
             G   +   I+PRSG + T+  L+   +  Y+L VT  +G        A          
Sbjct: 414 -PGEDAVYFKINPRSGLIVTARPLNTVKKEVYKLEVTNKEG-----DLKAQVTISIEDAN 467

Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQN 418
                F    Y+  + E  P GT V+T++A+D D  E+  + Y I   N           
Sbjct: 468 DHTPEFQQPLYDAYVNESVPVGTSVLTVSASDKDKGENGYITYSIASLNL---LPFVINQ 524

Query: 419 GRGLITVAQPLDFKQERR-YVLTVSATDSGG--RSDTAM-VQINITDANNYAPVFENAPY 474
             G+I+  + LDF+     Y   V A+D G   R ++ + V I I + N+ +P+FE    
Sbjct: 525 FTGVISTTEELDFESSPEIYRFIVRASDWGSPYRHESEVNVTIRIGNVNDNSPLFEKVAC 584

Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
              +  D P+G  +  VSA D D      + Y + S   NE        F +NP +G + 
Sbjct: 585 QGVISYDFPVGGHITAVSAIDIDE--LELVKYKIIS--GNEL-----GFFYLNPDSGVLQ 635

Query: 535 TNKLLDRETM--SGYLLTVTARDGGVPSLSDTTDVEISVV 572
             K L    +    + L +TA DG   +L+D   + ISV+
Sbjct: 636 LKKSLTNSGIKNGNFALRITATDG--ENLADPMSINISVL 673



 Score =  119 bits (286), Expect = 1e-24
 Identities = 117/453 (25%), Positives = 200/453 (44%), Gaps = 28/453 (6%)

Query: 443 ATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502
           AT S G   T  +  + T +   A V+EN+     V   + +G T++ +S    D+    
Sbjct: 28  ATVSQGLPGTGPLGFHFTHSIYNATVYENSAARTYVNSQSRMGITLIDLSW---DIKYRI 84

Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
            ++         E V   D  F+     G    + +L+RE    YLL V     G   L 
Sbjct: 85  -VSGDEEGFFKAEEVIIADFCFLRIRTKGG--NSAILNREIQDNYLLIVKGSVRG-EDLE 140

Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP 622
             T V I V+D+ND  P+F    Y+  I E   + TSV+QV ATDAD+G NG  +Y    
Sbjct: 141 AWTKVNIQVLDMNDLRPLFSPTTYSVTIAESTPLRTSVAQVTATDADIGSNGEFYYYFKN 200

Query: 623 KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG-----GTPPQSSTVIVHIKI 677
           K      F + P SGVI  +  L+ +    +DL+ +A+D      G    SST  +++ I
Sbjct: 201 K---VDLFSVHPTSGVISLSGRLNYDEKNRYDLEILAVDRGMKLYGNNGVSSTAKLYVHI 257

Query: 678 EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH-YSIKGGDDSNSFS 736
           E IN+  P         +  E  P   T   +   D D+G N  +   SI  GD  + F 
Sbjct: 258 ERINEHAPTIHVVTHVPFSLEKEP---TYAVVTVDDLDDGANGEIESVSIVAGDPLDQFF 314

Query: 737 LETRQGS--DKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNA 791
           L  ++G   ++ ++     +D+ES    Y L ++A    SP   + ++   +     D  
Sbjct: 315 L-AKEGKWLNEYKIKERKQIDWESFPYGYNLTLQAKDKGSPQKCSALKAVYIGNPTRDTV 373

Query: 792 PVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTL 851
           P+  + ++   +  +  P G    +     +  D ++Y++  G +A    +N  +G +  
Sbjct: 374 PIRFEKEVYDVSISEFSPPGVVVAIVKLSPEPID-VEYKLSPGEDAVYFKINPRSGLIVT 432

Query: 852 SPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884
           +  LNT   ++  +EV+  +G  ++KA + +S+
Sbjct: 433 ARPLNTVKKEVYKLEVTNKEG--DLKAQVTISI 463



 Score = 50.4 bits (115), Expect = 7e-04
 Identities = 80/349 (22%), Positives = 127/349 (36%), Gaps = 45/349 (12%)

Query: 1304 NGTLAGCPEKRSRCSSAPCYNGAECSDLWDT---YICDCKEGHTGKDCADSTGPPWRFGG 1360
            NG L  CP     C   PC    +C     +   ++C C  G  G +C+  T     F G
Sbjct: 3789 NGGL--CPGSNDPCVEKPCPGDMQCVSYEASRRPFLCQCPPGKLG-ECSGHTS--LSFAG 3843

Query: 1361 DGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMSIQLKSGLLHYSYNGETMY-------- 1412
            +  + +       +  +  AL +RT Q +  +M  +    ++    +G+  +        
Sbjct: 3844 NSYIKYRLSENSKEEDFKLALRLRTLQSNGIIMYTRANPCIILKIVDGKLWFQLDCGSGP 3903

Query: 1413 ----LPMATLSDGAWHRI--EIKWLGTDISVTVDY--GLRTVLMPMLANKIQGQYIGKIL 1464
                +    ++DG+WH +  E+    T +S+   Y    R  L     +     Y G ++
Sbjct: 3904 GILGISGRAVNDGSWHSVFLELNRNFTSLSLDDSYVERRRAPLYFQTLSTESSIYFGALV 3963

Query: 1465 IGG--LDTTAGLLASDVGFFEGCIQDVRIGTAQSLLN--RPTVRENV-----RDGCQSRA 1515
                    T   +   +  F+GC+  V +   +  L   R +  E V     + GC    
Sbjct: 3964 QADNIRSLTDTRVTQVLSGFQGCLDSVILNNNELPLQNKRSSFAEVVGLTELKLGCVLYP 4023

Query: 1516 D-CMLSICPPYSKCVTSWDSS--TCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTP 1568
            D C  S C     C T   S    CTC +   G  C   ++AC   PC     C  D   
Sbjct: 4024 DACKRSPCQHGGSC-TGLPSGGYQCTCLSQFTGRNCESEITACFPNPCRNGGSC--DPIG 4080

Query: 1569 KGYSCACEPGYTLTT--SGCIESGKEECPGGWWGGSACGPCACDVTRGY 1615
              + C C+ G T  T      E  +EEC  G    +  G   C+ T GY
Sbjct: 4081 NTFICNCKAGLTGVTCEEDINECEREECENGGSCVNVFGSFLCNCTPGY 4129



 Score = 48.0 bits (109), Expect = 0.004
 Identities = 46/197 (23%), Positives = 88/197 (44%), Gaps = 11/197 (5%)

Query: 680 INDSPPVFESDCLT-FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738
           IN   P F+    +   + E+ P+G  I +I+A+D D G N  V ++I  G+  + F+++
Sbjct: 719 INRQGPYFDKSFPSDVAVKEDLPVGANILKIKAYDADSGFNGKVLFTISDGNTDSCFNID 778

Query: 739 TRQGSDKAELVTMVDLDYE-SPRKKYELVIRAASPPLWNDVR-VEILVTDVNDNAPVMKD 796
              G    +L  ++ +D E +      + I     P  +  R + I V D NDN+PV   
Sbjct: 779 METG----QLKVLMPMDREHTDLYLLNITIYDLGNPQKSSWRLLTINVEDANDNSPVFIQ 834

Query: 797 FQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQ 854
                N  +         +V A D D+    ++ Y +L+  +     +N +TG + ++ Q
Sbjct: 835 DSYSVNILESSGIGTEIIQVEARDKDLGSNGEVTYSVLT--DTQQFAINSSTGIVYVADQ 892

Query: 855 LNTNVPKLATMEVSVTD 871
           L+       ++++   D
Sbjct: 893 LDRESKANYSLKIEARD 909



 Score = 39.5 bits (88), Expect = 1.3
 Identities = 12/39 (30%), Positives = 22/39 (56%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C E  + C    C NG  C +++ +++C+C  G+ G+ C
Sbjct: 4096 CEEDINECEREECENGGSCVNVFGSFLCNCTPGYVGQYC 4134


>UniRef50_A7S3G3 Cluster: Predicted protein; n=2; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 4187

 Score =  429 bits (1056), Expect = e-118
 Identities = 396/1357 (29%), Positives = 620/1357 (45%), Gaps = 120/1357 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + VLD ND +P F    Y AS+ E    G+ VL + A D D G N  V Y   LV+ D L
Sbjct: 2744 VQVLDINDVTPKFVSDPYLASIPENIDIGSKVLRVFAEDLDSGSNGMVTYA--LVSKDKL 2801

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           V++ F ID  +G + TR +LDREK   +   V+ATD  +    RL
Sbjct: 2802 ---------------VKEKFDIDQHTGWITTRGALDREKQPSFEFQVRATDNGTT---RL 2843

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +S  T+   ++D ND  P+FS+  +  SV ED  +  +  +  I ATD D+  N+ + Y 
Sbjct: 2844 TSLTTVRAIVLDVNDTPPKFSQSEFMASVKEDALIGQS--VTTITATDEDL--NTELYYF 2899

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I+ G+ Q +F I+  +G + +  +LD E V SY L I A DG   S +   Q+ I+I D 
Sbjct: 2900 ILSGDPQARFGIERKTGVIFVHGSLDRESVGSYDLNISASDGLFTSFA---QMKIDIEDA 2956

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN P    S++ E + EN P+G +++ V A DAD GVNAELTY++  + +         
Sbjct: 2957 NDNPPICTQSIYVEHIKENTPLGSTVLTVGATDADVGVNAELTYSVFGQGFG-----TFA 3011

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            +D ++G +    +LDRET+  Y  +V+A D G   ++  +               F    
Sbjct: 3012 VD-KNGKMTNLVELDRETRPFYNFMVSAADIGG--QACYSNISIHLDDVNDNRPLFSQSS 3068

Query: 371  YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
            Y   + ED P    ++ + A DAD   + +L Y +   +  G F+I  + G G+I++ +P
Sbjct: 3069 YFTAVYEDAPLKKVLLQVKADDADVGVNRKLTYSLVT-DAGGTFTI--ETGTGIISLEKP 3125

Query: 429  LDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
            L+ + +  Y L V   D G    S  A VQI + + N+  P F ++ Y  +V EDAPIG 
Sbjct: 3126 LNRELKENYTLNVEVMDGGTPPLSSIATVQIKVLNINDVPPEFSHSIYHGNVSEDAPIGN 3185

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
             V+ V A   +   N  ITY++     +         F I+ + G I  N+ LD ET   
Sbjct: 3186 EVVRVRAVSRESS-NDVITYAILRGADSGL-------FSIDRKNGTIHVNRKLDYETTKL 3237

Query: 547  YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
            Y LTV A D G P L  T+ V ISV D NDN P F ++ Y+A + E++ +GT V QV AT
Sbjct: 3238 YTLTVEASDAGPPVLRSTSYVRISVTDSNDNGPEFSEKRYSAKVDENSALGTFVLQVFAT 3297

Query: 607  DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
            D D G N +I Y +  +  +   F I   +GVI+ +  +DRE VA++ LK  A D G PP
Sbjct: 3298 DRDSGTNAQIKYSI-AEGNDAKKFKIVEETGVIKVSGDIDREEVASYRLKVRAQDQGLPP 3356

Query: 667  QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE-GPNAVVHYS 725
            Q +  +V I++ D+ND+ P F S  LT  +SE+S     +  +R HD D  G  A   ++
Sbjct: 3357 QVADTVVDIEVTDVNDNSPEFSSTNLTTVLSESSLPNAAVIHLRPHDRDALGNGAPYQFT 3416

Query: 726  IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVT 785
            +  GD S  F L +     K   V+  D  Y    +   LV     PP   +V + + + 
Sbjct: 3417 LISGDASR-FKLHSNGLITKIGDVSHSDGQY----RLRVLVADNGHPPQSTEVSITVKIA 3471

Query: 786  DVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNET 845
            +   + P +    +  N Y      G  GRV A D D  D L Y ++S   ++L+++++ 
Sbjct: 3472 ESKTHPPNVHPLTVYVNLYGSNLNGGVIGRVKATDKD-GDLLHYSLVSSEQSSLLMISD- 3529

Query: 846  TGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTA 905
                T+  + N + P    + VSVTD    + + + + V  IT E   +S+T+RL D++A
Sbjct: 3530 --EGTVRARANIS-PGTYNLNVSVTDKRYTVYSGVTVIVLNITPETQEHSVTLRLGDLSA 3586

Query: 906  EQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGD 965
              F+   L   +  +  ++  P  NI+++S+Q     + N L+V  + R+     G+   
Sbjct: 3587 GTFVEKSLEKCLLFIGKLLDVPAVNIHVWSMQP----SDNDLDVVIAVRK--RRKGM--- 3637

Query: 966  PSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGF 1025
                + P +L  ++        +   V+++    + C  + C  +  C  V K       
Sbjct: 3638 ----FKPLYLTRQLNGSHLAFEKNVGVRIVTVGLSQCRAQDCPTYLVCSDVYKPELKQIR 3693

Query: 1026 VNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG 1085
            V SD V +       S +C C +   G  C  I   A+       S C  G +C    E 
Sbjct: 3694 VMSDHVSYISYEHSRSHSCTCQDKNRG--CGAIQKCAT-------SPCAPGYKCKDFPE- 3743

Query: 1086 GILCQGCSIDAAYTTAVCELRARSFPVSSFLTFPGLKR---RHRIHLKLKFATQTTSGLL 1142
            G  C+ C +       +    AR+F   S++ +  LK    +    + L   T  + G L
Sbjct: 3744 GYQCK-CPL-----FHILGNNARTFNGDSYIRY-RLKETFDQPSRSIGLALKTVKSEGTL 3796

Query: 1143 LYNGRYNERHDFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGN-VGDGSWHTVEI 1201
            ++      ++D+  LE+        G   LRF F  G G   ++++ + V DG WH V +
Sbjct: 3797 VFAA---GQYDYSILEISK------GFIQLRFDF--GSGPGVVSIDWSPVNDGKWHHVAV 3845

Query: 1202 EYFNRTITMILDDCDKVLSLAGAADFGLKYACAN---FTRKVLPARCEIPTETCHRFLDL 1258
            E      T+ LD      S        +     N   F  KVL +R         +  + 
Sbjct: 3846 ERQGNHATVTLDYGKHQASGKSPGRMRILNLDGNSIYFGAKVLNSRI--------KRSEG 3897

Query: 1259 TGPLQIGGLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCS 1318
             G +   G      +  V  KD     S+ Y      +         T     +    C+
Sbjct: 3898 QGVIVENGFKGCMQNLNVNGKDLPMTGSNTYASGYPSNAELSTGTFWTRLQ-SDYVGACA 3956

Query: 1319 SAPCYNGAEC-SDLWDTYICDCKEGHTGKDCADSTGP 1354
            S+PC NG  C +   D +ICDC +G +GK C   + P
Sbjct: 3957 SSPCRNGGSCLAGQHDDFICDCPKGVSGKTCEVDSRP 3993



 Score =  366 bits (901), Expect = 4e-99
 Identities = 268/864 (31%), Positives = 422/864 (48%), Gaps = 71/864 (8%)

Query: 5    FCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIEL 64
            FC+  +++++D ND+ P+FE++ Y+ ++    + GT VL   A+D D   NA + Y I  
Sbjct: 2532 FCV-VEVHLIDENDNQPIFELKNYDTTISRSVTMGTPVLMTSASDPDASSNAALTYVI-- 2588

Query: 65   VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDRE-KVARYTVLVKATDQA 123
                                    VF I+  +G +     + RE +V  Y   V   D  
Sbjct: 2589 -----------------VGHQTPPVFTINAATGVI----QVSREPEVKSYNFFVLVKDGG 2627

Query: 124  SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183
            +P+   L S A++ + +++ +     F +  Y V+V E+  +    ++  +       G 
Sbjct: 2628 NPL---LRSIASVKITVLERDARILHFGKSKYDVTVGENAEM--GQIVTGLNLV-VPGGN 2681

Query: 184  NSAIRYAIIGG---NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240
               + Y II G   N   +F +DS +G V ++  LDYE    Y +++ A +  + ++   
Sbjct: 2682 PVDVDYRIIKGNNDNNDRKFGVDS-TGRVRVIGRLDYEIRNRYVMIVEA-NVSAINQIAR 2739

Query: 241  TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
            T +++ + D+ND  P+F +  +  S+ EN+ IG  ++RV A D D G N  +TY +  KD
Sbjct: 2740 TVVVVQVLDINDVTPKFVSDPYLASIPENIDIGSKVLRVFAEDLDSGSNGMVTYALVSKD 2799

Query: 301  YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
                V     ID  +GW+ T G LDRE Q  ++  V ATD G    ++  T         
Sbjct: 2800 KL--VKEKFDIDQHTGWITTRGALDREKQPSFEFQVRATDNGTTRLTSLTTVRAIVLDVN 2857

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420
                 F   ++   + ED   G  V T+TATD D +  L+Y I  G+ + RF I  +   
Sbjct: 2858 DTPPKFSQSEFMASVKEDALIGQSVTTITATDEDLNTELYYFILSGDPQARFGI--ERKT 2915

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
            G+I V   LD +    Y L +SA+D G  +  A ++I+I DAN+  P+   + Y   + E
Sbjct: 2916 GVIFVHGSLDRESVGSYDLNISASD-GLFTSFAQMKIDIEDANDNPPICTQSIYVEHIKE 2974

Query: 481  DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
            + P+G+TVL V ATD+DVG+NA++TYS+  +            F ++ + G +T    LD
Sbjct: 2975 NTPLGSTVLTVGATDADVGVNAELTYSVFGQGFG--------TFAVD-KNGKMTNLVELD 3025

Query: 541  RETMSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
            RET   Y   V+A D GG    S   ++ I + DVNDN P+F Q  Y   + EDA +   
Sbjct: 3026 RETRPFYNFMVSAADIGGQACYS---NISIHLDDVNDNRPLFSQSSYFTAVYEDAPLKKV 3082

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
            + QV A DADVG+N ++ Y L       G+F I+  +G+I   K L+RE    + L    
Sbjct: 3083 LLQVKADDADVGVNRKLTYSL--VTDAGGTFTIETGTGIISLEKPLNRELKENYTLNVEV 3140

Query: 660  IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
            +DGGTPP SS   V IK+ +IND PP F        +SE++PIG  +  +RA    E  N
Sbjct: 3141 MDGGTPPLSSIATVQIKVLNINDVPPEFSHSIYHGNVSEDAPIGNEVVRVRAVS-RESSN 3199

Query: 720  AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA--ASPPLWND 777
             V+ Y+I  G DS  FS++ + G+    +     LDYE+  K Y L + A  A PP+   
Sbjct: 3200 DVITYAILRGADSGLFSIDRKNGT----IHVNRKLDYET-TKLYTLTVEASDAGPPVLRS 3254

Query: 778  VR-VEILVTDVNDNAPVMKD----FQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRIL 832
               V I VTD NDN P   +     ++  N+    F +  F      D+    +++Y I 
Sbjct: 3255 TSYVRISVTDSNDNGPEFSEKRYSAKVDENSALGTFVLQVF--ATDRDSGTNAQIKYSIA 3312

Query: 833  SGNNANLILLNETTGSMTLSPQLN 856
             GN+A    + E TG + +S  ++
Sbjct: 3313 EGNDAKKFKIVEETGVIKVSGDID 3336



 Score =  353 bits (867), Expect = 5e-95
 Identities = 288/895 (32%), Positives = 436/895 (48%), Gaps = 77/895 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + + D ND SPVF+   YE ++ E  + G TV  + A+D+D G N  + Y I       +
Sbjct: 779  VKITDVNDCSPVFDKTVYEVTLPENITVGQTVTHVHASDKDQGTNGFITYQI-------V 831

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N                  FR++  SG +     LD E+   Y + ++A D +S  + ++
Sbjct: 832  NDFGGK-------------FRVNRISGVVSVGDYLDYEEQEMYKIEIQAMD-SSVDNQKV 877

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             ST  I V ++D NDN P    K + V+V ED+ V  N V+  I A+D D G    I ++
Sbjct: 878  GSTHVI-VTLLDINDNSPIVKPKKFNVTVQEDLLV--NAVVTSIHASDPDSGPGGEIEFS 934

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            +    +  +F+IDS SG + L + LD+EQ  +Y L +R  D GSP+     ++++N+ DV
Sbjct: 935  L--PESTRKFNIDSKSGVIRLRQRLDFEQKSTYNLTVRVTDKGSPALFTDVEVVVNVLDV 992

Query: 251  NDN--APRFYTS-LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            N+N  AP F    + + S++EN P+G  ++  +A D D      L Y + D   TG VD 
Sbjct: 993  NENSLAPVFSGGRILETSINENSPVGTVVISPKATDQDSWY---LKYAIIDG--TG-VDK 1046

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
             I IDP +G + T+G+LD E    Y L V A DG   P                    F 
Sbjct: 1047 FI-IDPDTGAIRTAGELDHEVADHYWLTVQAKDGESYPLYTNIPVLINIVDLNDEAPYFA 1105

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADEDNRL-HYEITGGNTRGRFSITSQNGRGLITVA 426
            P  Y   LAE+ P G+ VV +TA D D    L  Y IT GN +  F I  Q+G  LIT  
Sbjct: 1106 PSTYYPVLAENLPSGSSVVQVTAKDPDSGGSLLRYTITKGNEQNNFVIDPQSG--LITTL 1163

Query: 427  QPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
            +PLD + +  Y LTVSA+D G    S      + ITD N+  P F+   Y   VF     
Sbjct: 1164 RPLDREFKSEYKLTVSASDGGTPPVSTDVTFTVKITDENDNQPEFKEKQYVVGVFARQAT 1223

Query: 485  GTT--VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN-KLLDR 541
              +  +  V ATD D+G NA + YS++         + D +F+I+ ++G I TN  L+D 
Sbjct: 1224 SKSFGLYQVVATDEDIGSNADLRYSITK-------GNRDNKFIIDSRSGEIFTNVSLVDG 1276

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVND---NEPVFKQQLYTANIMEDALVGT 598
            E+   Y LT+ A D G+P LS +T+V I V+  N    N PVF  + Y+A+I ED  + +
Sbjct: 1277 ES---YDLTIVAEDNGLPKLSTSTNVLIDVIQGNKPSKNAPVFWNKQYSADIQEDKRINS 1333

Query: 599  SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
             V  +GA D D     +I Y +         F ID   G I    +LDRE  + + L+  
Sbjct: 1334 FVLIIGAEDPDFD---QITYNI-ASGNHGNKFTIDRYGGFITVAHSLDREEKSFYSLRVE 1389

Query: 659  AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
            A DG     +++V V I I D+ND+ P         +++ENS +GT +  ++  DPD G 
Sbjct: 1390 ATDGYN---TASVPVTINILDVNDNSPQPARREYRAHVAENSDVGTLVTTVK--DPDAGV 1444

Query: 719  NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLW 775
            N  V Y I     + S SL   + S    ++T+  LDYE+  +++ L I+A+    P   
Sbjct: 1445 NGEVEYCIVQTAKAESASLFKIE-SHSGRILTVKPLDYET-MQEHVLTIKASDRGIPKRE 1502

Query: 776  NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG--RVPAYDAD--VTDKLQYRI 831
                V + V DVND+ P       +F +  D          RV A D D     KL+Y I
Sbjct: 1503 TLFSVVVSVDDVNDHKPEF--LSPLFESEVDVSAKAGTAILRVIATDKDDGTNSKLKYSI 1560

Query: 832  LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886
            +SGN    + +++ +G + ++ +L+T V + A    S   G   +K  + + V++
Sbjct: 1561 VSGNTNKSLSVDQNSGVVKVAGRLSTLVHQYALKVQSTDGGEPPLKTQVDVKVKV 1615



 Score =  325 bits (799), Expect = 9e-87
 Identities = 260/802 (32%), Positives = 392/802 (48%), Gaps = 80/802 (9%)

Query: 8    HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
            H  + +LD ND+SP+ + +++  +V+E       V ++ A+D D G   E+E+++     
Sbjct: 881  HVIVTLLDINDNSPIVKPKKFNVTVQEDLLVNAVVTSIHASDPDSGPGGEIEFSL----- 935

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
                PE                F ID +SG +  R  LD E+ + Y + V+ TD+ SP  
Sbjct: 936  ----PESTRK------------FNIDSKSGVIRLRQRLDFEQKSTYNLTVRVTDKGSPA- 978

Query: 128  DRLSSTATIHVNIIDDNDN--YPQFS-EKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184
              L +   + VN++D N+N   P FS  +    S++E+  V    V+   KATD D   +
Sbjct: 979  --LFTDVEVVVNVLDVNENSLAPVFSGGRILETSINENSPV--GTVVISPKATDQD---S 1031

Query: 185  SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
              ++YAII G    +F ID  +G +     LD+E    Y L ++A+DG S        +L
Sbjct: 1032 WYLKYAIIDGTGVDKFIIDPDTGAIRTAGELDHEVADHYWLTVQAKDGESYPLYTNIPVL 1091

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
            INI D+ND AP F  S +   ++EN+P G S+V+V A D D G  + L YT+T     GN
Sbjct: 1092 INIVDLNDEAPYFAPSTYYPVLAENLPSGSSVVQVTAKDPDSG-GSLLRYTIT----KGN 1146

Query: 305  VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
                  IDP+SG + T   LDRE +++Y+L V+A+DGG PP S   T             
Sbjct: 1147 EQNNFVIDPQSGLITTLRPLDREFKSEYKLTVSASDGGTPPVSTDVTFTVKITDENDNQP 1206

Query: 365  XFMPGQYEVEL----AEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420
             F   QY V +    A  +  G   V  T  D   +  L Y IT GN   +F I S++G 
Sbjct: 1207 EFKEKQYVVGVFARQATSKSFGLYQVVATDEDIGSNADLRYSITKGNRDNKFIIDSRSGE 1266

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDAN---NYAPVFENAPYT 475
             + T    +D +    Y LT+ A D+G    S +  V I++   N     APVF N  Y+
Sbjct: 1267 -IFTNVSLVDGES---YDLTIVAEDNGLPKLSTSTNVLIDVIQGNKPSKNAPVFWNKQYS 1322

Query: 476  ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
            A + ED  I + VL++ A D D     QITY+++S        +H  +F I+   G IT 
Sbjct: 1323 ADIQEDKRINSFVLIIGAEDPDFD---QITYNIAS-------GNHGNKFTIDRYGGFITV 1372

Query: 536  NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
               LDRE  S Y L V A DG     + +  V I+++DVNDN P   ++ Y A++ E++ 
Sbjct: 1373 AHSLDREEKSFYSLRVEATDG---YNTASVPVTINILDVNDNSPQPARREYRAHVAENSD 1429

Query: 596  VGTSVSQVGATDADVGLNGRIHYELDPKDREEGS--FVIDPASGVIRTNKALDRESVATH 653
            VGT V+ V   D D G+NG + Y +    + E +  F I+  SG I T K LD E++  H
Sbjct: 1430 VGTLVTTV--KDPDAGVNGEVEYCIVQTAKAESASLFKIESHSGRILTVKPLDYETMQEH 1487

Query: 654  DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713
             L   A D G P + +   V + ++D+ND  P F S      +  ++  GT I  + A D
Sbjct: 1488 VLTIKASDRGIPKRETLFSVVVSVDDVNDHKPEFLSPLFESEVDVSAKAGTAILRVIATD 1547

Query: 714  PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK--AELVTMVDLDYESPRKKYELVIRA-- 769
             D+G N+ + YSI  G+ + S S++   G  K    L T+V         +Y L +++  
Sbjct: 1548 KDDGTNSKLKYSIVSGNTNKSLSVDQNSGVVKVAGRLSTLV--------HQYALKVQSTD 1599

Query: 770  -ASPPLWNDVRVEILVTDVNDN 790
               PPL   V V++ V  +  N
Sbjct: 1600 GGEPPLKTQVDVKVKVRGIVKN 1621



 Score =  314 bits (772), Expect = 2e-83
 Identities = 260/876 (29%), Positives = 411/876 (46%), Gaps = 74/876 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ ++D ND++P F+   Y AS+   AS G  V  + ATD D G   ++ Y+I       
Sbjct: 2329 RVVLMDANDNAPRFDKSMYAASILGSASPGQFVTRILATDPDEGDAKKLRYSI------- 2381

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                             +  F+ID +SG +     +  ++   Y + V+ +D        
Sbjct: 2382 ------------TGGQGRQHFQIDSQSGVITLSRVVGIKQGKVYGLDVEVSDSVH----- 2424

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
              ST+ + V I D ND+ P FSE  Y VS +E  +  +   +  + ATD D G  + + Y
Sbjct: 2425 -VSTSKVRVIIGDTNDHSPIFSEDVYKVSFNE--NYPEGTFVTMVSATDLDSGNYAHLTY 2481

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLV----IRAQDGGSPSRSNTTQLLI 245
            +I   +   +F ID+ SG   L   L +++  S + +    IRA DGG   R     + +
Sbjct: 2482 SIDSVDAMRKFRIDADSG--MLYSRLMFDRENSSQAIMSVPIRATDGG--GRFGFCVVEV 2537

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
            ++ D NDN P F    +  ++S +V +G  ++   A D D   NA LTY +      G+ 
Sbjct: 2538 HLIDENDNQPIFELKNYDTTISRSVTMGTPVLMTSASDPDASSNAALTYVI-----VGHQ 2592

Query: 306  DLPI-TIDPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
              P+ TI+  +G +    Q+ RE + K Y   V   DGG+P   + A+            
Sbjct: 2593 TPPVFTINAATGVI----QVSREPEVKSYNFFVLVKDGGNPLLRSIASVKITVLERDARI 2648

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLT-ATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422
              F   +Y+V + E+   G  V  L           + Y I  GN          +  G 
Sbjct: 2649 LHFGKSKYDVTVGENAEMGQIVTGLNLVVPGGNPVDVDYRIIKGNNDNNDRKFGVDSTGR 2708

Query: 423  ITVAQPLDFKQERRYVLTVSATDSG-GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
            + V   LD++   RYV+ V A  S   +    +V + + D N+  P F + PY AS+ E+
Sbjct: 2709 VRVIGRLDYEIRNRYVMIVEANVSAINQIARTVVVVQVLDINDVTPKFVSDPYLASIPEN 2768

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
              IG+ VL V A D D G N  +TY+L   +S + +    ++F I+  TG ITT   LDR
Sbjct: 2769 IDIGSKVLRVFAEDLDSGSNGMVTYAL---VSKDKLV--KEKFDIDQHTGWITTRGALDR 2823

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
            E    +   V A D G   L+  T V   V+DVND  P F Q  + A++ EDAL+G SV+
Sbjct: 2824 EKQPSFEFQVRATDNGTTRLTSLTTVRAIVLDVNDTPPKFSQSEFMASVKEDALIGQSVT 2883

Query: 602  QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
             + ATD D  LN  ++Y +   D  +  F I+  +GVI  + +LDRESV ++DL   A D
Sbjct: 2884 TITATDED--LNTELYYFILSGD-PQARFGIERKTGVIFVHGSLDRESVGSYDLNISASD 2940

Query: 662  GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
            G     +S   + I IED ND+PP+        +I EN+P+G+T+  + A D D G NA 
Sbjct: 2941 G---LFTSFAQMKIDIEDANDNPPICTQSIYVEHIKENTPLGSTVLTVGATDADVGVNAE 2997

Query: 722  VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDV 778
            + YS+  G    +F+++        ++  +V+LD E+ R  Y  ++ AA       ++++
Sbjct: 2998 LTYSV-FGQGFGTFAVD-----KNGKMTNLVELDRET-RPFYNFMVSAADIGGQACYSNI 3050

Query: 779  RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNN 836
             + +   DVNDN P+          Y+D        +V A DAD  V  KL Y +++ + 
Sbjct: 3051 SIHL--DDVNDNRPLFSQSSYFTAVYEDAPLKKVLLQVKADDADVGVNRKLTYSLVT-DA 3107

Query: 837  ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
                 +   TG ++L   LN  + +  T+ V V DG
Sbjct: 3108 GGTFTIETGTGIISLEKPLNRELKENYTLNVEVMDG 3143



 Score =  306 bits (751), Expect = 6e-81
 Identities = 233/756 (30%), Positives = 361/756 (47%), Gaps = 45/756 (5%)

Query: 144  NDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSID 203
            N ++P F      + + E   +    V+++  ATD D G N  + Y+I+ G+    F+I+
Sbjct: 680  NRHHPVFRSHDQNIHISESTPIAT--VVSQFMATDEDKGYNGLVLYSIVEGDVDSVFNIN 737

Query: 204  SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263
              +G++++   LD E + SY L I A D G   +S  T L + I DVND +P F  ++++
Sbjct: 738  MFTGELTVAMPLDRETISSYTLNISAVDCGKHRKSAYTILNVKITDVNDCSPVFDKTVYE 797

Query: 264  ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323
             ++ EN+ +G ++  V A D D+G N  +TY + + D+ G       ++  SG V     
Sbjct: 798  VTLPENITVGQTVTHVHASDKDQGTNGFITYQIVN-DFGGK----FRVNRISGVVSVGDY 852

Query: 324  LDRETQAKYQLLVTATDGG-DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382
            LD E Q  Y++ + A D   D  +  +                  P ++ V + ED    
Sbjct: 853  LDYEEQEMYKIEIQAMDSSVDNQKVGSTHVIVTLLDINDNSPIVKPKKFNVTVQEDLLVN 912

Query: 383  TPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
              V ++ A+D D       E +   +  +F+I S++  G+I + Q LDF+Q+  Y LTV 
Sbjct: 913  AVVTSIHASDPDSGPGGEIEFSLPESTRKFNIDSKS--GVIRLRQRLDFEQKSTYNLTVR 970

Query: 443  ATDSGGRS--DTAMVQINITDA--NNYAPVFENAP-YTASVFEDAPIGTTVLVVSATDSD 497
             TD G  +      V +N+ D   N+ APVF        S+ E++P+GT V+   ATD D
Sbjct: 971  VTDKGSPALFTDVEVVVNVLDVNENSLAPVFSGGRILETSINENSPVGTVVISPKATDQD 1030

Query: 498  VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG 557
               +  + Y++   I    V     +F+I+P TGAI T   LD E    Y LTV A+DG 
Sbjct: 1031 ---SWYLKYAI---IDGTGV----DKFIIDPDTGAIRTAGELDHEVADHYWLTVQAKDGE 1080

Query: 558  VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617
               L     V I++VD+ND  P F    Y   + E+   G+SV QV A D D G    + 
Sbjct: 1081 SYPLYTNIPVLINIVDLNDEAPYFAPSTYYPVLAENLPSGSSVVQVTAKDPDSG-GSLLR 1139

Query: 618  YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
            Y +  K  E+ +FVIDP SG+I T + LDRE  + + L   A DGGTPP S+ V   +KI
Sbjct: 1140 YTI-TKGNEQNNFVIDPQSGLITTLRPLDREFKSEYKLTVSASDGGTPPVSTDVTFTVKI 1198

Query: 678  EDINDSPPVFESDCLTFYISENSPIGTTIG--EIRAHDPDEGPNAVVHYSIKGGDDSNSF 735
             D ND+ P F+       +        + G  ++ A D D G NA + YSI  G+  N F
Sbjct: 1199 TDENDNQPEFKEKQYVVGVFARQATSKSFGLYQVVATDEDIGSNADLRYSITKGNRDNKF 1258

Query: 736  SLETRQGSDKAELVTMVDL-DYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVN--- 788
             +++R G    E+ T V L D ES    Y+L I A     P L     V I V   N   
Sbjct: 1259 IIDSRSG----EIFTNVSLVDGES----YDLTIVAEDNGLPKLSTSTNVLIDVIQGNKPS 1310

Query: 789  DNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGS 848
             NAPV  + Q   +  +D   +  F  +   +    D++ Y I SGN+ N   ++   G 
Sbjct: 1311 KNAPVFWNKQYSADIQED-KRINSFVLIIGAEDPDFDQITYNIASGNHGNKFTIDRYGGF 1369

Query: 849  MTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884
            +T++  L+       ++ V  TDG N     + +++
Sbjct: 1370 ITVAHSLDREEKSFYSLRVEATDGYNTASVPVTINI 1405



 Score =  301 bits (740), Expect = 1e-79
 Identities = 241/811 (29%), Positives = 376/811 (46%), Gaps = 60/811 (7%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            F ID   G +    SLDRE+ + Y++ V+ATD  +  S        + +NI+D NDN PQ
Sbjct: 1361 FTIDRYGGFITVAHSLDREEKSFYSLRVEATDGYNTAS------VPVTINILDVNDNSPQ 1414

Query: 150  FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG---GNTQMQFSIDSLS 206
             + + Y   V E+  V    ++  +K  D D G N  + Y I+      +   F I+S S
Sbjct: 1415 PARREYRAHVAENSDV--GTLVTTVK--DPDAGVNGEVEYCIVQTAKAESASLFKIESHS 1470

Query: 207  GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266
            G +  VK LDYE ++ + L I+A D G P R     +++++ DVND+ P F + LF+  V
Sbjct: 1471 GRILTVKPLDYETMQEHVLTIKASDRGIPKRETLFSVVVSVDDVNDHKPEFLSPLFESEV 1530

Query: 267  SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326
              +   G +I+RV A D D+G N++L Y++     +GN +  +++D  SG V  +G+L  
Sbjct: 1531 DVSAKAGTAILRVIATDKDDGTNSKLKYSIV----SGNTNKSLSVDQNSGVVKVAGRLST 1586

Query: 327  ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386
                +Y L V +TDGG+PP   T                F   +YEV L E+ PP   + 
Sbjct: 1587 LVH-QYALKVQSTDGGEPPLK-TQVDVKVKVRGIVKNFAFEKPKYEVSLPENSPPDQAIA 1644

Query: 387  TLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446
            T+            YEI  G +      T Q   G+I   +  D ++     L + A  +
Sbjct: 1645 TVVYNGI----LPVYEIVPGRSPCWRDFTVQRQSGVIISKKSFDAEEVTHCKLEIRANST 1700

Query: 447  GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV-------LVVSATDSDVG 499
             G+  + +V + I D N+  P+FE+A  T  V E +P GT V       LV  ATD D+ 
Sbjct: 1701 DGQHSSTLVIVTIQDKNDNQPIFEHARITGHVTEGSPQGTAVLDHKGSQLVAVATDQDIS 1760

Query: 500  INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
               ++TY +    + +        F I+P TGAITT K+LD E    Y   +   D G P
Sbjct: 1761 -GDKLTYEIVETSARDV-------FSIHPATGAITTAKVLDYEVTPQYAFKIKVTDSGNP 1812

Query: 560  SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619
             LS   DV+I V D+ND  PVF    Y A +   +  GT V+ V ATD D   N  + + 
Sbjct: 1813 RLSAFADVKIHVTDINDIAPVFSASTYHATVYLPSYAGTRVTMVTATDGDSAAN--LTFS 1870

Query: 620  LDPKDREEGSFVIDPASGVIR-TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678
            L  +D E   F ++P +GV+  +N AL R    T+ +K    DG     ++   V I+ E
Sbjct: 1871 LARQDTE--LFAVNPLTGVVTVSNAALLRRD--TYTIKLTVSDGN---HTAHARVRIRCE 1923

Query: 679  DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738
            ++  S   F     +  + E   + + +  +RA     G  + + Y+I   + S  F + 
Sbjct: 1924 NLPSSDLQFSRKNYSASVREGVSVDSELVTVRALGYPIG--STITYTII--NPSELFHIV 1979

Query: 739  TRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMK 795
               G     +    DLD ES    Y+++++A   + PP      V + V D NDN PV  
Sbjct: 1980 PSTG--VMSIRAGFDLDRES-IDAYQVIVQARDDSVPPNVAQAAVHVQVIDRNDNQPVFI 2036

Query: 796  DFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRI-LSGNNANLILLNETTGSMTLSPQ 854
            +                 G+  A DAD+      R  L G +     ++  TG + +   
Sbjct: 2037 NSPYFIVLQLGVAQGTIIGQAQATDADIGSNANLRYDLIGGDPGYFSISRKTGEVVVRRT 2096

Query: 855  L-NTNVPKLATMEVSVTDGVNEIKAMMQLSV 884
            L +  VP+L T+ V  TDG+   +A++++ V
Sbjct: 2097 LDDVKVPRLFTLMVEATDGLFRTEAVVKIKV 2127



 Score =  301 bits (739), Expect = 2e-79
 Identities = 272/918 (29%), Positives = 417/918 (45%), Gaps = 82/918 (8%)

Query: 17   NDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAX 76
            N H PVF        + E     T V    ATD+D G N  V Y+I  V  D        
Sbjct: 680  NRHHPVFRSHDQNIHISESTPIATVVSQFMATDEDKGYNGLVLYSI--VEGD-------- 729

Query: 77   XXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATI 136
                     V  VF I+  +G L     LDRE ++ YT+ + A D       R S+   +
Sbjct: 730  ---------VDSVFNINMFTGELTVAMPLDRETISSYTLNISAVDCG---KHRKSAYTIL 777

Query: 137  HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNT 196
            +V I D ND  P F +  Y V++ E+I+V     +  + A+D D G N  I Y I+  + 
Sbjct: 778  NVKITDVNDCSPVFDKTVYEVTLPENITV--GQTVTHVHASDKDQGTNGFITYQIV-NDF 834

Query: 197  QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS-NTTQLLINIRDVNDNAP 255
              +F ++ +SG VS+   LDYE+   Y++ I+A D    ++   +T +++ + D+NDN+P
Sbjct: 835  GGKFRVNRISGVVSVGDYLDYEEQEMYKIEIQAMDSSVDNQKVGSTHVIVTLLDINDNSP 894

Query: 256  RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315
                  F  +V E++ +   +  + A D D G   E+ +++ +     N      ID +S
Sbjct: 895  IVKPKKFNVTVQEDLLVNAVVTSIHASDPDSGPGGEIEFSLPESTRKFN------IDSKS 948

Query: 316  GWVYTSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXXXXFMPGQ-YE 372
            G +    +LD E ++ Y L V  TD G P                       F  G+  E
Sbjct: 949  GVIRLRQRLDFEQKSTYNLTVRVTDKGSPALFTDVEVVVNVLDVNENSLAPVFSGGRILE 1008

Query: 373  VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432
              + E+ P GT V++  ATD D    L Y I  G    +F I      G I  A  LD +
Sbjct: 1009 TSINENSPVGTVVISPKATDQD-SWYLKYAIIDGTGVDKFIIDPDT--GAIRTAGELDHE 1065

Query: 433  QERRYVLTVSATD--SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
                Y LTV A D  S        V INI D N+ AP F  + Y   + E+ P G++V+ 
Sbjct: 1066 VADHYWLTVQAKDGESYPLYTNIPVLINIVDLNDEAPYFAPSTYYPVLAENLPSGSSVVQ 1125

Query: 491  VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550
            V+A D D G  + + Y+++    NE        FVI+PQ+G ITT + LDRE  S Y LT
Sbjct: 1126 VTAKDPDSG-GSLLRYTITK--GNE-----QNNFVIDPQSGLITTLRPLDREFKSEYKLT 1177

Query: 551  VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS--VSQVGATDA 608
            V+A DGG P +S      + + D NDN+P FK++ Y   +        S  + QV ATD 
Sbjct: 1178 VSASDGGTPPVSTDVTFTVKITDENDNQPEFKEKQYVVGVFARQATSKSFGLYQVVATDE 1237

Query: 609  DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL-DRESVATHDLKAVAIDGGTPPQ 667
            D+G N  + Y +  K   +  F+ID  SG I TN +L D ES   +DL  VA D G P  
Sbjct: 1238 DIGSNADLRYSI-TKGNRDNKFIIDSRSGEIFTNVSLVDGES---YDLTIVAEDNGLPKL 1293

Query: 668  SSTVIVHIKIEDIN---DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
            S++  V I +   N    + PVF +   +  I E+  I + +  I A DPD      + Y
Sbjct: 1294 STSTNVLIDVIQGNKPSKNAPVFWNKQYSADIQEDKRINSFVLIIGAEDPDFDQ---ITY 1350

Query: 725  SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILV 784
            +I  G+  N F+++   G     +     LD E  +  Y L + A        V V I +
Sbjct: 1351 NIASGNHGNKFTIDRYGGF----ITVAHSLDREE-KSFYSLRVEATDGYNTASVPVTINI 1405

Query: 785  TDVNDNA--PVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILL 842
             DVNDN+  P  ++++       D   +    + P  DA V  +++Y I+    A     
Sbjct: 1406 LDVNDNSPQPARREYRAHVAENSDVGTLVTTVKDP--DAGVNGEVEYCIVQTAKAE---- 1459

Query: 843  NETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLND 902
                 S +L  ++ ++  ++ T++    + + E    ++ S R I +   L S+ V ++D
Sbjct: 1460 -----SASLF-KIESHSGRILTVKPLDYETMQEHVLTIKASDRGIPKRETLFSVVVSVDD 1513

Query: 903  MT--AEQFLSPLLGFFID 918
            +     +FLSPL    +D
Sbjct: 1514 VNDHKPEFLSPLFESEVD 1531



 Score =  289 bits (710), Expect = 6e-76
 Identities = 238/865 (27%), Positives = 401/865 (46%), Gaps = 62/865 (7%)

Query: 15   DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
            D NDHSP+F    Y+ S  E    GT V  + ATD D G  A + Y+I+ V A       
Sbjct: 2436 DTNDHSPIFSEDVYKVSFNENYPEGTFVTMVSATDLDSGNYAHLTYSIDSVDA------- 2488

Query: 75   AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR--YTVLVKATDQASPVSDRLSS 132
                           FRID  SG L +R   DRE  ++   +V ++ATD           
Sbjct: 2489 ------------MRKFRIDADSGMLYSRLMFDRENSSQAIMSVPIRATDGGGRF-----G 2531

Query: 133  TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192
               + V++ID+NDN P F  K Y  ++    SVT    +    A+D D  +N+A+ Y I+
Sbjct: 2532 FCVVEVHLIDENDNQPIFELKNYDTTISR--SVTMGTPVLMTSASDPDASSNAALTYVIV 2589

Query: 193  GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252
            G  T   F+I++ +G + + +     +V+SY   +  +DGG+P   +   + I + + + 
Sbjct: 2590 GHQTPPVFTINAATGVIQVSRE---PEVKSYNFFVLVKDGGNPLLRSIASVKITVLERDA 2646

Query: 253  NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312
                F  S +  +V EN  +G  +  +       G   ++ Y +  K    N D    +D
Sbjct: 2647 RILHFGKSKYDVTVGENAEMGQIVTGLNLV-VPGGNPVDVDYRII-KGNNDNNDRKFGVD 2704

Query: 313  PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE 372
              +G V   G+LD E + +Y ++V A       + A                 F+   Y 
Sbjct: 2705 -STGRVRVIGRLDYEIRNRYVMIVEANVSA-INQIARTVVVVQVLDINDVTPKFVSDPYL 2762

Query: 373  VELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
              + E+   G+ V+ + A D D   +  + Y +   +   +         G IT    LD
Sbjct: 2763 ASIPENIDIGSKVLRVFAEDLDSGSNGMVTYALVSKDKLVKEKFDIDQHTGWITTRGALD 2822

Query: 431  FKQERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYAPVFENAPYTASVFEDAPIGTTV 488
             +++  +   V ATD+G    T++  +   + D N+  P F  + + ASV EDA IG +V
Sbjct: 2823 REKQPSFEFQVRATDNGTTRLTSLTTVRAIVLDVNDTPPKFSQSEFMASVKEDALIGQSV 2882

Query: 489  LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
              ++ATD D  +N ++ Y +   +S +  A    +F I  +TG I  +  LDRE++  Y 
Sbjct: 2883 TTITATDED--LNTELYYFI---LSGDPQA----RFGIERKTGVIFVHGSLDRESVGSYD 2933

Query: 549  LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
            L ++A DG   S +    ++I + D NDN P+  Q +Y  +I E+  +G++V  VGATDA
Sbjct: 2934 LNISASDGLFTSFA---QMKIDIEDANDNPPICTQSIYVEHIKENTPLGSTVLTVGATDA 2990

Query: 609  DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
            DVG+N  + Y +    +  G+F +D  +G +     LDRE+   ++    A D G     
Sbjct: 2991 DVGVNAELTYSV--FGQGFGTFAVD-KNGKMTNLVELDRETRPFYNFMVSAADIGGQACY 3047

Query: 669  STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
            S + +H  ++D+ND+ P+F        + E++P+   + +++A D D G N  + YS+  
Sbjct: 3048 SNISIH--LDDVNDNRPLFSQSSYFTAVYEDAPLKKVLLQVKADDADVGVNRKLTYSLV- 3104

Query: 729  GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVN 788
             D   +F++ET  G    E     +L  E+     E V+   +PPL +   V+I V ++N
Sbjct: 3105 TDAGGTFTIETGTGIISLEKPLNRELK-ENYTLNVE-VMDGGTPPLSSIATVQIKVLNIN 3162

Query: 789  DNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVT-DKLQYRILSGNNANLILLNETT 846
            D  P      I   N  +  P+G    RV A   + + D + Y IL G ++ L  ++   
Sbjct: 3163 DVPPEF-SHSIYHGNVSEDAPIGNEVVRVRAVSRESSNDVITYAILRGADSGLFSIDRKN 3221

Query: 847  GSMTLSPQLNTNVPKLATMEVSVTD 871
            G++ ++ +L+    KL T+ V  +D
Sbjct: 3222 GTIHVNRKLDYETTKLYTLTVEASD 3246



 Score =  286 bits (702), Expect = 5e-75
 Identities = 263/895 (29%), Positives = 430/895 (48%), Gaps = 89/895 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            IN++D ND +P F    Y   + E   SG++V+ + A D D G +  + YTI      T 
Sbjct: 1092 INIVDLNDEAPYFAPSTYYPVLAENLPSGSSVVQVTAKDPDSGGSL-LRYTI------TK 1144

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
              E             Q+ F ID +SG + T   LDRE  + Y + V A+D  +P    +
Sbjct: 1145 GNE-------------QNNFVIDPQSGLITTLRPLDREFKSEYKLTVSASDGGTPP---V 1188

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S+  T  V I D+NDN P+F EK Y V V    + + +  + ++ ATD D+G+N+ +RY+
Sbjct: 1189 STDVTFTVKITDENDNQPEFKEKQYVVGVFARQATSKSFGLYQVVATDEDIGSNADLRYS 1248

Query: 191  IIGGNTQMQFSIDSLSGDV-SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            I  GN   +F IDS SG++ + V  +D E   SY L I A+D G P  S +T +LI++  
Sbjct: 1249 ITKGNRDNKFIIDSRSGEIFTNVSLVDGE---SYDLTIVAEDNGLPKLSTSTNVLIDVIQ 1305

Query: 250  VN---DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
             N    NAP F+   +   + E+  I   ++ + A D D     ++TY +     +GN  
Sbjct: 1306 GNKPSKNAPVFWNKQYSADIQEDKRINSFVLIIGAEDPDFD---QITYNIA----SGNHG 1358

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
               TID   G++  +  LDRE ++ Y L V ATDG +   +A+                 
Sbjct: 1359 NKFTIDRYGGFITVAHSLDREEKSFYSLRVEATDGYN---TASVPVTINILDVNDNSPQP 1415

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHY---EITGGNTRGRFSITSQNGRGLI 423
               +Y   +AE+   GT V T+   DA  +  + Y   +     +   F I S +GR ++
Sbjct: 1416 ARREYRAHVAENSDVGTLVTTVKDPDAGVNGEVEYCIVQTAKAESASLFKIESHSGR-IL 1474

Query: 424  TVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
            TV +PLD++  + +VLT+ A+D G   R     V +++ D N++ P F +  + + V   
Sbjct: 1475 TV-KPLDYETMQEHVLTIKASDRGIPKRETLFSVVVSVDDVNDHKPEFLSPLFESEVDVS 1533

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
            A  GT +L V ATD D G N+++ YS+ S  +N++++  DQ   +    G ++T      
Sbjct: 1534 AKAGTAILRVIATDKDDGTNSKLKYSIVSGNTNKSLS-VDQNSGVVKVAGRLST------ 1586

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
              +  Y L V + DGG P L    DV++ V  +  N   F++  Y  ++ E++    ++ 
Sbjct: 1587 -LVHQYALKVQSTDGGEPPLKTQVDVKVKVRGIVKNF-AFEKPKYEVSLPENSPPDQAI- 1643

Query: 602  QVGATDADVGLNGRIH-YELDP-KDREEGSFVIDPASGVIRTNKALDRESVATH---DLK 656
                  A V  NG +  YE+ P +      F +   SGVI + K+ D E V TH   +++
Sbjct: 1644 ------ATVVYNGILPVYEIVPGRSPCWRDFTVQRQSGVIISKKSFDAEEV-THCKLEIR 1696

Query: 657  AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR------ 710
            A + DG    Q S+ +V + I+D ND+ P+FE   +T +++E SP GT + + +      
Sbjct: 1697 ANSTDG----QHSSTLVIVTIQDKNDNQPIFEHARITGHVTEGSPQGTAVLDHKGSQLVA 1752

Query: 711  -AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPRKKYEL-VI 767
             A D D   + +  Y I      + FS+    G+    + T   LDYE +P+  +++ V 
Sbjct: 1753 VATDQDISGDKLT-YEIVETSARDVFSIHPATGA----ITTAKVLDYEVTPQYAFKIKVT 1807

Query: 768  RAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKL 827
             + +P L     V+I VTD+ND APV          Y   +       V A D D    L
Sbjct: 1808 DSGNPRLSAFADVKIHVTDINDIAPVFSASTYHATVYLPSYAGTRVTMVTATDGDSAANL 1867

Query: 828  QYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQL 882
             +  L+  +  L  +N  TG +T+S           T++++V+DG +   A +++
Sbjct: 1868 TFS-LARQDTELFAVNPLTGVVTVSNAALLR-RDTYTIKLTVSDGNHTAHARVRI 1920



 Score =  283 bits (693), Expect = 6e-74
 Identities = 240/818 (29%), Positives = 381/818 (46%), Gaps = 62/818 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + + D ND+ P+FE  +    V EG+  GT VL  K      G       T + ++ D L
Sbjct: 1711 VTIQDKNDNQPIFEHARITGHVTEGSPQGTAVLDHK------GSQLVAVATDQDISGDKL 1764

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
              E             +DVF I   +GA+ T   LD E   +Y   +K TD  +P   RL
Sbjct: 1765 TYE-------IVETSARDVFSIHPATGAITTAKVLDYEVTPQYAFKIKVTDSGNP---RL 1814

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S+ A + +++ D ND  P FS  TY  +V   +       +  + ATD D  AN  + ++
Sbjct: 1815 SAFADVKIHVTDINDIAPVFSASTYHATVY--LPSYAGTRVTMVTATDGDSAAN--LTFS 1870

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            +   +T++ F+++ L+G V+ V      +  +Y + +   DG   + +   ++ I   ++
Sbjct: 1871 LARQDTEL-FAVNPLTGVVT-VSNAALLRRDTYTIKLTVSDGNHTAHA---RVRIRCENL 1925

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
              +  +F    +  SV E V +   +V V+A     G  + +TYT+ +     ++ +P T
Sbjct: 1926 PSSDLQFSRKNYSASVREGVSVDSELVTVRALGYPIG--STITYTIINPSELFHI-VPST 1982

Query: 311  --IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
              +  R+G+      LDRE+   YQ++V A D   PP  A A               F+ 
Sbjct: 1983 GVMSIRAGF-----DLDRESIDAYQVIVQARDDSVPPNVAQAAVHVQVIDRNDNQPVFIN 2037

Query: 369  GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
              Y + L      GT +    ATDAD   +  L Y++ GG+  G FSI+ + G   + V 
Sbjct: 2038 SPYFIVLQLGVAQGTIIGQAQATDADIGSNANLRYDLIGGDP-GYFSISRKTGE--VVVR 2094

Query: 427  QPLD-FKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
            + LD  K  R + L V ATD   R++ A+V+I + D     PVF+   ++  + ED PIG
Sbjct: 2095 RTLDDVKVPRLFTLMVEATDGLFRTE-AVVKIKVVDKET--PVFDQLSFSKVLAEDTPIG 2151

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
            + V  V+A   +    A I YS++     + V     QF I+ +TG +T    LD ET +
Sbjct: 2152 SEVTSVTARSPN---GAGILYSITG---GDPV----NQFSIDFKTGVVTLVSSLDYETRT 2201

Query: 546  GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
             Y L V A D    S SD   V+++V DVND  P F + LY A I E   V T+V  V A
Sbjct: 2202 KYKLVVRATDARTSSHSDVA-VDVTVTDVNDVAPAFNRSLYLATISESTPVDTAVVTVKA 2260

Query: 606  TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
             D D G+N  I+Y +    R    F ID  SGV+   K+LD ES   H++  VA D G P
Sbjct: 2261 IDGDSGINKEINYFIQNVSRVGAFFKIDKKSGVVFVAKSLDYESRVVHEMIIVAADEGKP 2320

Query: 666  PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
              +    V + + D ND+ P F+       I  ++  G  +  I A DPDEG    + YS
Sbjct: 2321 SLTGETRVRVVLMDANDNAPRFDKSMYAASILGSASPGQFVTRILATDPDEGDAKKLRYS 2380

Query: 726  IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVT 785
            I GG     F ++++ G     ++T+  +      K Y L +  +     +  +V +++ 
Sbjct: 2381 ITGGQGRQHFQIDSQSG-----VITLSRVVGIKQGKVYGLDVEVSDSVHVSTSKVRVIIG 2435

Query: 786  DVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDAD 822
            D ND++P+  +  +   ++ + +P G F   V A D D
Sbjct: 2436 DTNDHSPIFSE-DVYKVSFNENYPEGTFVTMVSATDLD 2472



 Score =  261 bits (639), Expect = 2e-67
 Identities = 264/930 (28%), Positives = 415/930 (44%), Gaps = 86/930 (9%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I+V D ND +PVF    Y A+V   + +GT V  + ATD D   N     T  L   DT
Sbjct: 1821 KIHVTDINDIAPVFSASTYHATVYLPSYAGTRVTMVTATDGDSAAN----LTFSLARQDT 1876

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLVKATDQASPVSD 128
                              ++F ++  +G + ++ A+L R    R T  +K T     VSD
Sbjct: 1877 ------------------ELFAVNPLTGVVTVSNAALLR----RDTYTIKLT-----VSD 1909

Query: 129  RLSSTATIHVNIIDDN--DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
              + TA   V I  +N   +  QFS K Y+ SV E +SV D+ ++  ++A    +G  S 
Sbjct: 1910 G-NHTAHARVRIRCENLPSSDLQFSRKNYSASVREGVSV-DSELVT-VRALGYPIG--ST 1964

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVK--TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
            I Y II  N    F I   +G +S+     LD E + +Y+++++A+D   P       + 
Sbjct: 1965 ITYTII--NPSELFHIVPSTGVMSIRAGFDLDRESIDAYQVIVQARDDSVPPNVAQAAVH 2022

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
            + + D NDN P F  S +   +   V  G  I + QA DAD G NA L Y     D  G 
Sbjct: 2023 VQVIDRNDNQPVFINSPYFIVLQLGVAQGTIIGQAQATDADIGSNANLRY-----DLIGG 2077

Query: 305  VDLPITIDPRSGWVYTSGQLDR-ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
                 +I  ++G V     LD  +    + L+V ATDG                      
Sbjct: 2078 DPGYFSISRKTGEVVVRRTLDDVKVPRLFTLMVEATDG-----LFRTEAVVKIKVVDKET 2132

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423
              F    +   LAED P G+ V ++TA   +    L Y ITGG+   +FSI  +   G++
Sbjct: 2133 PVFDQLSFSKVLAEDTPIGSEVTSVTARSPNGAGIL-YSITGGDPVNQFSIDFKT--GVV 2189

Query: 424  TVAQPLDFKQERRYVLTVSATD--SGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
            T+   LD++   +Y L V ATD  +   SD A V + +TD N+ AP F  + Y A++ E 
Sbjct: 2190 TLVSSLDYETRTKYKLVVRATDARTSSHSDVA-VDVTVTDVNDVAPAFNRSLYLATISES 2248

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
             P+ T V+ V A D D GIN +I Y + +      V+     F I+ ++G +   K LD 
Sbjct: 2249 TPVDTAVVTVKAIDGDSGINKEINYFIQN------VSRVGAFFKIDKKSGVVFVAKSLDY 2302

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
            E+   + + + A D G PSL+  T V + ++D NDN P F + +Y A+I+  A  G  V+
Sbjct: 2303 ESRVVHEMIIVAADEGKPSLTGETRVRVVLMDANDNAPRFDKSMYAASILGSASPGQFVT 2362

Query: 602  QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
            ++ ATD D G   ++ Y +      +  F ID  SGVI  ++ +  +    + L     D
Sbjct: 2363 RILATDPDEGDAKKLRYSITGGQGRQ-HFQIDSQSGVITLSRVVGIKQGKVYGLDVEVSD 2421

Query: 662  GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
                   ST  V + I D ND  P+F  D      +EN P GT +  + A D D G  A 
Sbjct: 2422 S---VHVSTSKVRVIIGDTNDHSPIFSEDVYKVSFNENYPEGTFVTMVSATDLDSGNYAH 2478

Query: 722  VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRV 780
            + YSI   D    F ++   G   + L  M D +  S +    + IRA      +    V
Sbjct: 2479 LTYSIDSVDAMRKFRIDADSGMLYSRL--MFDRE-NSSQAIMSVPIRATDGGGRFGFCVV 2535

Query: 781  EILVTDVNDNAPV--MKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNN 836
            E+ + D NDN P+  +K++    +  +      P     A D D +    L Y I+    
Sbjct: 2536 EVHLIDENDNQPIFELKNYDTTIS--RSVTMGTPVLMTSASDPDASSNAALTYVIVGHQT 2593

Query: 837  ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE-IKAMMQLSVRLITEEMLLNS 895
              +  +N  TG + +S +      K     V V DG N  ++++  + + ++  +  +  
Sbjct: 2594 PPVFTINAATGVIQVSREPEV---KSYNFFVLVKDGGNPLLRSIASVKITVLERDARILH 2650

Query: 896  ITVRLNDMTAEQFLSPLLGFFIDGLAAIIP 925
                  D+T  +  +  +G  + GL  ++P
Sbjct: 2651 FGKSKYDVTVGE--NAEMGQIVTGLNLVVP 2678



 Score =  260 bits (637), Expect = 4e-67
 Identities = 223/833 (26%), Positives = 360/833 (43%), Gaps = 43/833 (5%)

Query: 63   ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122
            E+ +    +P  A            + F ID ++G +   +SLD E   +Y ++V+ATD 
Sbjct: 2153 EVTSVTARSPNGAGILYSITGGDPVNQFSIDFKTGVVTLVSSLDYETRTKYKLVVRATDA 2212

Query: 123  ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
             +       S   + V + D ND  P F+   Y  ++ E   V D  V+  +KA D D G
Sbjct: 2213 RTSSH----SDVAVDVTVTDVNDVAPAFNRSLYLATISESTPV-DTAVVT-VKAIDGDSG 2266

Query: 183  ANSAIRYAIIG-GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
             N  I Y I         F ID  SG V + K+LDYE    + ++I A D G PS +  T
Sbjct: 2267 INKEINYFIQNVSRVGAFFKIDKKSGVVFVAKSLDYESRVVHEMIIVAADEGKPSLTGET 2326

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
            ++ + + D NDNAPRF  S++  S+  +   G  + R+ A D DEG   +L Y++T    
Sbjct: 2327 RVRVVLMDANDNAPRFDKSMYAASILGSASPGQFVTRILATDPDEGDAKKLRYSITG--- 2383

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
             G       ID +SG +  S  +  +    Y L V  +D       +T+           
Sbjct: 2384 -GQGRQHFQIDSQSGVITLSRVVGIKQGKVYGLDVEVSDS---VHVSTSKVRVIIGDTND 2439

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNG 419
                F    Y+V   E+ P GT V  ++ATD D  N  H  Y I   +   +F I + +G
Sbjct: 2440 HSPIFSEDVYKVSFNENYPEGTFVTMVSATDLDSGNYAHLTYSIDSVDAMRKFRIDADSG 2499

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479
                 +    +   +    + + ATD GGR    +V++++ D N+  P+FE   Y  ++ 
Sbjct: 2500 MLYSRLMFDRENSSQAIMSVPIRATDGGGRFGFCVVEVHLIDENDNQPIFELKNYDTTIS 2559

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ-FVINPQTGAITTNKL 538
                +GT VL+ SA+D D   NA +TY +        V H     F IN  TG I  ++ 
Sbjct: 2560 RSVTMGTPVLMTSASDPDASSNAALTYVI--------VGHQTPPVFTINAATGVIQVSR- 2610

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
                 +  Y   V  +DGG P L     V+I+V++ +     F +  Y   + E+A +G 
Sbjct: 2611 --EPEVKSYNFFVLVKDGGNPLLRSIASVKITVLERDARILHFGKSKYDVTVGENAEMGQ 2668

Query: 599  SVSQVGATDADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
             V+ +       G    + Y +     D  +  F +D ++G +R    LD E +    + 
Sbjct: 2669 IVTGLNLV-VPGGNPVDVDYRIIKGNNDNNDRKFGVD-STGRVRVIGRLDYE-IRNRYVM 2725

Query: 657  AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
             V  +     Q +  +V +++ DIND  P F SD     I EN  IG+ +  + A D D 
Sbjct: 2726 IVEANVSAINQIARTVVVVQVLDINDVTPKFVSDPYLASIPENIDIGSKVLRVFAEDLDS 2785

Query: 717  GPNAVVHYSIKGGDD--SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---AS 771
            G N +V Y++   D      F ++   G     + T   LD E  +  +E  +RA    +
Sbjct: 2786 GSNGMVTYALVSKDKLVKEKFDIDQHTG----WITTRGALDREK-QPSFEFQVRATDNGT 2840

Query: 772  PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRI 831
              L +   V  +V DVND  P     + + +  +D         + A D D+  +L Y I
Sbjct: 2841 TRLTSLTTVRAIVLDVNDTPPKFSQSEFMASVKEDALIGQSVTTITATDEDLNTELYYFI 2900

Query: 832  LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884
            LSG+      +   TG + +   L+        + +S +DG+    A M++ +
Sbjct: 2901 LSGDPQARFGIERKTGVIFVHGSLDRESVGSYDLNISASDGLFTSFAQMKIDI 2953



 Score =  238 bits (583), Expect = 1e-60
 Identities = 189/611 (30%), Positives = 297/611 (48%), Gaps = 45/611 (7%)

Query: 181 VGANSAIRYAIIGGNTQMQFSIDSLSG------DVSLVKTLDYEQVRSYRLVIRAQDGGS 234
           V + + + + II GN Q  FS+DS         D+   K L+ E V SY L +  QD  +
Sbjct: 23  VYSKNHVDFIIISGNEQGMFSVDSRQVSDFNFMDIKTSKRLNRESVASYELNVVVQDKRT 82

Query: 235 PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294
               + T++ I + D NDN P F    + +++ E++P+  SI R++A DAD G N  + Y
Sbjct: 83  KRTLDRTKVNITVDDSNDNRPIFLKKKYLKTIPEDIPMHTSIARIEAVDADVGPNGLIYY 142

Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354
           +  +K  +        I+P SG V  + +L    +  ++L V A D   PP    ++   
Sbjct: 143 SFKEKTTS------FAINPISGVVSVAQKLSNSARI-HRLTVVARDRALPPSKPKSSRNC 195

Query: 355 XXXXXXXXXXXFMPG---QYEVELAEDEPPGTPVVTLTATDADEDNR---LHYEITGGNT 408
                      F P    + +++   +   G    TL   D D+ +       EIT GN 
Sbjct: 196 QLIVNVQAVNQFSPEFSVKTQLQNVSEGTSGIVYATLGIIDKDKGSNGDIDRVEITSGNL 255

Query: 409 RGRFSITSQNGRGLITVAQPLDFK-QERRYVLTVSATDSGG--RSDTAMVQINITDANNY 465
            G FSI S      + V +PLD +     Y +T++A D G   R+ + ++++N+ D N+ 
Sbjct: 256 DGAFSIKSSPNDYAVQVIKPLDRELAPFGYNVTLTAYDKGTPVRNGSYVLRVNVLDENDN 315

Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525
            P F  + Y  ++ E API T VL V ATD D G N  I Y ++    NE       +F 
Sbjct: 316 NPEFNQSRYITNLSELAPIHTPVLRVLATDKDAGSNGNIMYVITR--GNEL-----GKFE 368

Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS---DTTDVEISVVDVNDNEPVFK 582
           IN +TG I T   LD E+   + LTV A D GVP  S    T  V ++++D ND++P FK
Sbjct: 369 INSKTGQIYTKGDLDYESRQRFDLTVAALD-GVPLQSRKISTVPVVVNILDANDHDPEFK 427

Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642
              Y  ++ ED   GTSV  V A D D G NG++ Y L   +     F I+P +G+IRT 
Sbjct: 428 APEYRKDLYEDLTPGTSVFTVSAEDLDSGGNGKVRYSL--ANLRPVPFEIEPDTGIIRTT 485

Query: 643 KALDRESVATH--DLKAVAIDGGTPPQSST-VIVHIKIEDINDSPPVFESDCLTFYISEN 699
             LDR++      +L+  A D GTP +  T  +V ++++++ND+ PV +       +  N
Sbjct: 486 TNLDRDTGLPEFINLQVRASDFGTPLRRETETLVKMRVKEMNDNAPVLKQFKCNILVDRN 545

Query: 700 SPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758
           +P+G  I  + A D D    +  + Y    G+   +FSL+ + G    EL T   L    
Sbjct: 546 APVGVLITTVTAIDIDISDKDQSLMYKSTFGNTGKAFSLDPKTG----ELRTARSL--RG 599

Query: 759 PRKKYELVIRA 769
            ++++ L+I+A
Sbjct: 600 LQREFTLIIKA 610



 Score =  225 bits (550), Expect = 1e-56
 Identities = 195/616 (31%), Positives = 290/616 (47%), Gaps = 50/616 (8%)

Query: 87  QDVFRIDGRSGA------LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNI 140
           Q +F +D R  +      + T   L+RE VA Y + V   D+ +    R      +++ +
Sbjct: 39  QGMFSVDSRQVSDFNFMDIKTSKRLNRESVASYELNVVVQDKRTK---RTLDRTKVNITV 95

Query: 141 IDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQF 200
            D NDN P F +K Y  ++ EDI +  +  IA+I+A DADVG N  I Y+     T   F
Sbjct: 96  DDSNDNRPIFLKKKYLKTIPEDIPM--HTSIARIEAVDADVGPNGLIYYSFKEKTT--SF 151

Query: 201 SIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD----GGSPSRSNTTQLLINIRDVNDNAPR 256
           +I+ +SG VS+ + L     R +RL + A+D       P  S   QL++N++ VN  +P 
Sbjct: 152 AINPISGVVSVAQKLS-NSARIHRLTVVARDRALPPSKPKSSRNCQLIVNVQAVNQFSPE 210

Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD--LPITIDPR 314
           F      ++VSE    G     +   D D+G N ++      +  +GN+D    I   P 
Sbjct: 211 FSVKTQLQNVSEGTS-GIVYATLGIIDKDKGSNGDIDRV---EITSGNLDGAFSIKSSPN 266

Query: 315 SGWVYTSGQLDRE-TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373
              V     LDRE     Y + +TA D G P R+ +                F   +Y  
Sbjct: 267 DYAVQVIKPLDRELAPFGYNVTLTAYDKGTPVRNGSYVLRVNVLDENDNNPEFNQSRYIT 326

Query: 374 ELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431
            L+E  P  TPV+ + ATD D   +  + Y IT GN  G+F I S+ G+  I     LD+
Sbjct: 327 NLSELAPIHTPVLRVLATDKDAGSNGNIMYVITRGNELGKFEINSKTGQ--IYTKGDLDY 384

Query: 432 KQERRYVLTVSATD----SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
           +  +R+ LTV+A D       +  T  V +NI DAN++ P F+   Y   ++ED   GT+
Sbjct: 385 ESRQRFDLTVAALDGVPLQSRKISTVPVVVNILDANDHDPEFKAPEYRKDLYEDLTPGTS 444

Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET-MSG 546
           V  VSA D D G N ++ YSL++             F I P TG I T   LDR+T +  
Sbjct: 445 VFTVSAEDLDSGGNGKVRYSLAN--------LRPVPFEIEPDTGIIRTTTNLDRDTGLPE 496

Query: 547 YL-LTVTARDGGVPSLSDT-TDVEISVVDVNDNEPVFKQQLYTANIMED--ALVGTSVSQ 602
           ++ L V A D G P   +T T V++ V ++NDN PV KQ  +  NI+ D  A VG  ++ 
Sbjct: 497 FINLQVRASDFGTPLRRETETLVKMRVKEMNDNAPVLKQ--FKCNILVDRNAPVGVLITT 554

Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
           V A D D+    +             +F +DP +G +RT ++L R       L   A DG
Sbjct: 555 VTAIDIDISDKDQSLMYKSTFGNTGKAFSLDPKTGELRTARSL-RGLQREFTLIIKATDG 613

Query: 663 -GTPPQSSTVIVHIKI 677
               P +  VI+ I I
Sbjct: 614 IQESPDTHPVILKISI 629



 Score =  177 bits (431), Expect = 4e-42
 Identities = 174/581 (29%), Positives = 260/581 (44%), Gaps = 44/581 (7%)

Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377
           + TS +L+RE+ A Y+L V   D                         F+  +Y   + E
Sbjct: 57  IKTSKRLNRESVASYELNVVVQDKRTKRTLDRTKVNITVDDSNDNRPIFLKKKYLKTIPE 116

Query: 378 DEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435
           D P  T +  + A DAD   +  ++Y      T   F+I   +G  +++VAQ L     R
Sbjct: 117 DIPMHTSIARIEAVDADVGPNGLIYYSFKEKTTS--FAINPISG--VVSVAQKLS-NSAR 171

Query: 436 RYVLTVSATDSG------GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
            + LTV A D          S    + +N+   N ++P F       +V E    G    
Sbjct: 172 IHRLTVVARDRALPPSKPKSSRNCQLIVNVQAVNQFSPEFSVKTQLQNVSEGTS-GIVYA 230

Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI--NPQTGAITTNKLLDRETMS-G 546
            +   D D G N  I      EI++    + D  F I  +P   A+   K LDRE    G
Sbjct: 231 TLGIIDKDKGSNGDID---RVEITS---GNLDGAFSIKSSPNDYAVQVIKPLDRELAPFG 284

Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
           Y +T+TA D G P  + +  + ++V+D NDN P F Q  Y  N+ E A + T V +V AT
Sbjct: 285 YNVTLTAYDKGTPVRNGSYVLRVNVLDENDNNPEFNQSRYITNLSELAPIHTPVLRVLAT 344

Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
           D D G NG I Y +  +  E G F I+  +G I T   LD ES    DL   A+DG  P 
Sbjct: 345 DKDAGSNGNIMYVIT-RGNELGKFEINSKTGQIYTKGDLDYESRQRFDLTVAALDG-VPL 402

Query: 667 QS---STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
           QS   STV V + I D ND  P F++      + E+   GT++  + A D D G N  V 
Sbjct: 403 QSRKISTVPVVVNILDANDHDPEFKAPEYRKDLYEDLTPGTSVFTVSAEDLDSGGNGKVR 462

Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY-ELVIRAAS--PPLWNDVR- 779
           YS+     +N   +      D   + T  +LD ++   ++  L +RA+    PL  +   
Sbjct: 463 YSL-----ANLRPVPFEIEPDTGIIRTTTNLDRDTGLPEFINLQVRASDFGTPLRRETET 517

Query: 780 -VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADVTDK---LQYRILSG 834
            V++ V ++NDNAPV+K F+      ++  PVG     V A D D++DK   L Y+   G
Sbjct: 518 LVKMRVKEMNDNAPVLKQFKCNILVDRNA-PVGVLITTVTAIDIDISDKDQSLMYKSTFG 576

Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE 875
           N      L+  TG +  +  L   + +  T+ +  TDG+ E
Sbjct: 577 NTGKAFSLDPKTGELRTARSLR-GLQREFTLIIKATDGIQE 616



 Score =  176 bits (428), Expect = 8e-42
 Identities = 167/576 (28%), Positives = 250/576 (43%), Gaps = 52/576 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V D ND+ P+F  ++Y  ++ E     T++  ++A D D+G N  + Y+ +  T    
Sbjct: 93  ITVDDSNDNRPIFLKKKYLKTIPEDIPMHTSIARIEAVDADVGPNGLIYYSFKEKTTS-- 150

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDRE-KVARYTVLVKATDQASPVSDR 129
                              F I+  SG +     L    ++ R TV+  A D+A P S  
Sbjct: 151 -------------------FAINPISGVVSVAQKLSNSARIHRLTVV--ARDRALPPSKP 189

Query: 130 LSS-TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI- 187
            SS    + VN+   N   P+FS KT   +V E    T   V A +   D D G+N  I 
Sbjct: 190 KSSRNCQLIVNVQAVNQFSPEFSVKTQLQNVSEG---TSGIVYATLGIIDKDKGSNGDID 246

Query: 188 RYAIIGGNTQMQFSIDSLSGD--VSLVKTLDYEQVR-SYRLVIRAQDGGSPSRSNTTQLL 244
           R  I  GN    FSI S   D  V ++K LD E     Y + + A D G+P R+ +  L 
Sbjct: 247 RVEITSGNLDGAFSIKSSPNDYAVQVIKPLDRELAPFGYNVTLTAYDKGTPVRNGSYVLR 306

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           +N+ D NDN P F  S +  ++SE  PI   ++RV A D D G N  + Y +T  +  G 
Sbjct: 307 VNVLDENDNNPEFNQSRYITNLSELAPIHTPVLRVLATDKDAGSNGNIMYVITRGNELGK 366

Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG--DPPRSATATXXXXXXXXXXX 362
            +    I+ ++G +YT G LD E++ ++ L V A DG      + +T             
Sbjct: 367 FE----INSKTGQIYTKGDLDYESRQRFDLTVAALDGVPLQSRKISTVPVVVNILDANDH 422

Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG-RFSITSQNGRG 421
              F   +Y  +L ED  PGT V T++A D D         +  N R   F I    G  
Sbjct: 423 DPEFKAPEYRKDLYEDLTPGTSVFTVSAEDLDSGGNGKVRYSLANLRPVPFEIEPDTGII 482

Query: 422 LITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASV 478
             T     D        L V A+D G    R    +V++ + + N+ APV +       V
Sbjct: 483 RTTTNLDRDTGLPEFINLQVRASDFGTPLRRETETLVKMRVKEMNDNAPVLKQFKCNILV 542

Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             +AP+G  +  V+A D D+    Q +    S   N   A     F ++P+TG + T + 
Sbjct: 543 DRNAPVGVLITTVTAIDIDISDKDQ-SLMYKSTFGNTGKA-----FSLDPKTGELRTARS 596

Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDV--EISVV 572
           L R     + L + A D G+    DT  V  +IS+V
Sbjct: 597 L-RGLQREFTLIIKATD-GIQESPDTHPVILKISIV 630



 Score =  161 bits (392), Expect = 2e-37
 Identities = 162/600 (27%), Positives = 269/600 (44%), Gaps = 57/600 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           +NV   N  SP F ++    +V EG +SG    TL   D+D G N +++  +E+ +    
Sbjct: 199 VNVQAVNQFSPEFSVKTQLQNVSEG-TSGIVYATLGIIDKDKGSNGDID-RVEITSG--- 253

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA-RYTVLVKATDQASPVSDR 129
           N + A             V +             LDRE     Y V + A D+ +PV + 
Sbjct: 254 NLDGAFSIKSSPNDYAVQVIK------------PLDRELAPFGYNVTLTAYDKGTPVRN- 300

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
              +  + VN++D+NDN P+F++  Y  ++ E ++    PV+ ++ ATD D G+N  I Y
Sbjct: 301 --GSYVLRVNVLDENDNNPEFNQSRYITNLSE-LAPIHTPVL-RVLATDKDAGSNGNIMY 356

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG--SPSRSNTTQLLINI 247
            I  GN   +F I+S +G +     LDYE  + + L + A DG      + +T  +++NI
Sbjct: 357 VITRGNELGKFEINSKTGQIYTKGDLDYESRQRFDLTVAALDGVPLQSRKISTVPVVVNI 416

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            D ND+ P F    +++ + E++  G S+  V A D D G N ++ Y++ +        +
Sbjct: 417 LDANDHDPEFKAPEYRKDLYEDLTPGTSVFTVSAEDLDSGGNGKVRYSLANLR-----PV 471

Query: 308 PITIDPRSGWVYTSGQLDRETQAK--YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
           P  I+P +G + T+  LDR+T       L V A+D G P R  T T              
Sbjct: 472 PFEIEPDTGIIRTTTNLDRDTGLPEFINLQVRASDFGTPLRRETETLVKMRVKEMNDNAP 531

Query: 366 FMPGQYEVELAEDE--PPGTPVVTLTATD---ADEDNRLHYEITGGNTRGRFSITSQNGR 420
            +  Q++  +  D   P G  + T+TA D   +D+D  L Y+ T GNT   FS+  + G 
Sbjct: 532 VLK-QFKCNILVDRNAPVGVLITTVTAIDIDISDKDQSLMYKSTFGNTGKAFSLDPKTGE 590

Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRS-DTAMVQINIT-DANNYAPVFENAPYTASV 478
             +  A+ L   Q R + L + ATD    S DT  V + I+      A   +N   T  V
Sbjct: 591 --LRTARSLRGLQ-REFTLIIKATDGIQESPDTHPVILKISIVGGRQARKLQNHVSTKCV 647

Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE---AVAHHDQQFVINPQTG-AIT 534
             D+P+    L +            + ++ ++++ N        HDQ   I+  T  A  
Sbjct: 648 --DSPLYAKALKIKQEQKSYSSLQPLIFA-TAKLHNRHHPVFRSHDQNIHISESTPIATV 704

Query: 535 TNKLLDRETMSGY--LLTVTARDGGVPSLSDTT--DVEISVVDVNDNEPVFKQQLYTANI 590
            ++ +  +   GY  L+  +  +G V S+ +      E++V    D E +     YT NI
Sbjct: 705 VSQFMATDEDKGYNGLVLYSIVEGDVDSVFNINMFTGELTVAMPLDRETI---SSYTLNI 761



 Score =  160 bits (389), Expect = 4e-37
 Identities = 144/543 (26%), Positives = 240/543 (44%), Gaps = 39/543 (7%)

Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL----ITVA 426
           Y   + E  P GTPV           N + + I  GN +G FS+ S+         I  +
Sbjct: 1   YSAFIPEITPIGTPVKCDLKMGVYSKNHVDFIIISGNEQGMFSVDSRQVSDFNFMDIKTS 60

Query: 427 QPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
           + L+ +    Y L V   D   +   D   V I + D+N+  P+F    Y  ++ ED P+
Sbjct: 61  KRLNRESVASYELNVVVQDKRTKRTLDRTKVNITVDDSNDNRPIFLKKKYLKTIPEDIPM 120

Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            T++  + A D+DVG N  I YS   + ++         F INP +G ++  + L     
Sbjct: 121 HTSIARIEAVDADVGPNGLIYYSFKEKTTS---------FAINPISGVVSVAQKLSNSAR 171

Query: 545 SGYLLTVTARDGGV----PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
             + LTV ARD  +    P  S    + ++V  VN   P F  +    N+ E    G   
Sbjct: 172 I-HRLTVVARDRALPPSKPKSSRNCQLIVNVQAVNQFSPEFSVKTQLQNVSE-GTSGIVY 229

Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVI--DPASGVIRTNKALDRE-SVATHDLKA 657
           + +G  D D G NG I          +G+F I   P    ++  K LDRE +   +++  
Sbjct: 230 ATLGIIDKDKGSNGDIDRVEITSGNLDGAFSIKSSPNDYAVQVIKPLDRELAPFGYNVTL 289

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
            A D GTP ++ + ++ + + D ND+ P F        +SE +PI T +  + A D D G
Sbjct: 290 TAYDKGTPVRNGSYVLRVNVLDENDNNPEFNQSRYITNLSELAPIHTPVLRVLATDKDAG 349

Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLW- 775
            N  + Y I  G++   F + ++ G    ++ T  DLDYES R++++L + A    PL  
Sbjct: 350 SNGNIMYVITRGNELGKFEINSKTG----QIYTKGDLDYES-RQRFDLTVAALDGVPLQS 404

Query: 776 ---NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYR 830
              + V V + + D ND+ P  K  +   + Y+D  P      V A D D     K++Y 
Sbjct: 405 RKISTVPVVVNILDANDHDPEFKAPEYRKDLYEDLTPGTSVFTVSAEDLDSGGNGKVRYS 464

Query: 831 ILSGNNANLILLNETTGSMTLSPQL--NTNVPKLATMEVSVTDGVNEIKAMMQLSVRLIT 888
            L+        +   TG +  +  L  +T +P+   ++V  +D    ++   +  V++  
Sbjct: 465 -LANLRPVPFEIEPDTGIIRTTTNLDRDTGLPEFINLQVRASDFGTPLRRETETLVKMRV 523

Query: 889 EEM 891
           +EM
Sbjct: 524 KEM 526



 Score =  134 bits (325), Expect = 3e-29
 Identities = 100/335 (29%), Positives = 158/335 (47%), Gaps = 30/335 (8%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++NVLD ND++P F   +Y  ++ E A   T VL + ATD+D G N  + Y I     + 
Sbjct: 306 RVNVLDENDNNPEFNQSRYITNLSELAPIHTPVLRVLATDKDAGSNGNIMYVI--TRGNE 363

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
           L                   F I+ ++G + T+  LD E   R+ + V A D   P+  R
Sbjct: 364 LGK-----------------FEINSKTGQIYTKGDLDYESRQRFDLTVAALD-GVPLQSR 405

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             ST  + VNI+D ND+ P+F    Y   + ED+  T    +  + A D D G N  +RY
Sbjct: 406 KISTVPVVVNILDANDHDPEFKAPEYRKDLYEDL--TPGTSVFTVSAEDLDSGGNGKVRY 463

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQ--VRSYRLVIRAQDGGSPSRSNTTQLL-IN 246
           + +     + F I+  +G +     LD +        L +RA D G+P R  T  L+ + 
Sbjct: 464 S-LANLRPVPFEIEPDTGIIRTTTNLDRDTGLPEFINLQVRASDFGTPLRRETETLVKMR 522

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
           ++++NDNAP          V  N P+G  I  V A D D    ++   ++  K   GN  
Sbjct: 523 VKEMNDNAPVLKQFKCNILVDRNAPVGVLITTVTAIDID---ISDKDQSLMYKSTFGNTG 579

Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341
              ++DP++G + T+  L R  Q ++ L++ ATDG
Sbjct: 580 KAFSLDPKTGELRTARSL-RGLQREFTLIIKATDG 613



 Score = 97.5 bits (232), Expect = 5e-18
 Identities = 77/277 (27%), Positives = 131/277 (47%), Gaps = 28/277 (10%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I+V D ND+ P F  ++Y A V E ++ GT VL + ATD+D G NA+++Y+I       
Sbjct: 3259 RISVTDSNDNGPEFSEKRYSAKVDENSALGTFVLQVFATDRDSGTNAQIKYSI------- 3311

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                DA              F+I   +G +     +DRE+VA Y + V+A DQ  P   +
Sbjct: 3312 AEGNDAKK------------FKIVEETGVIKVSGDIDREEVASYRLKVRAQDQGLP--PQ 3357

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA-IR 188
            ++ T  + + + D NDN P+FS    T  + E  S   N  +  ++  D D   N A  +
Sbjct: 3358 VADT-VVDIEVTDVNDNSPEFSSTNLTTVLSE--SSLPNAAVIHLRPHDRDALGNGAPYQ 3414

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            + +I G+   +F + S +G ++ +  + +     YRL +   D G P +S    + + I 
Sbjct: 3415 FTLISGDAS-RFKLHS-NGLITKIGDVSHSD-GQYRLRVLVADNGHPPQSTEVSITVKIA 3471

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD 285
            +   + P  +      ++  +   G  I RV+A D D
Sbjct: 3472 ESKTHPPNVHPLTVYVNLYGSNLNGGVIGRVKATDKD 3508


>UniRef50_UPI00006A0F37 Cluster: dachsous 2 isoform 1; n=1; Xenopus
            tropicalis|Rep: dachsous 2 isoform 1 - Xenopus tropicalis
          Length = 3630

 Score =  420 bits (1035), Expect = e-115
 Identities = 281/900 (31%), Positives = 456/900 (50%), Gaps = 53/900 (5%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I V D ND++P+F  + Y  S+ E     +T+L + A D+D G N+++ Y     +   
Sbjct: 2110 KIIVSDFNDNAPIFTQEVYTVSLNENIPVNSTILRVSANDKDEGSNSQITYYFAASSKQA 2169

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSD 128
            +N                  F ID  SG + T+ +LD EK+ R + + + A D  SP   
Sbjct: 2170 MN-----------------TFIIDSISGEVKTKENLDFEKIEREFQIQIMAKDHGSP--- 2209

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             L+S+  + + I+D NDN P FS++ Y VS++E+I +  N  I  + A D D G NS IR
Sbjct: 2210 SLNSSTNLRICIVDFNDNLPVFSQEVYKVSINENIPI--NSTILYVSANDKDEGINSQIR 2267

Query: 189  YAIIGGNTQM--QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            Y     + Q+   F I+S+SG +   + LD+E+ + Y + ++A D  +   + T  + I 
Sbjct: 2268 YYFSTSSKQILNTFIINSISGAIMTKENLDFEKTKLYEISVQANDQYT-GETGTALIRIT 2326

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            + D NDN P F   +++ S++EN+P+  +++ V A D DEG+N++LTY+ +    +    
Sbjct: 2327 VTDANDNFPMFSQEIYKVSINENMPLNSTVLYVSASDKDEGINSQLTYSFSSA--SKQAT 2384

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
                I+P+SG + TS  LDRE ++ Y + + ATD G PP S+  T              F
Sbjct: 2385 NAFAINPQSGEIVTSSTLDREMKSHYDITIQATDKGSPPLSSRKTIRLDVSDINDNAPVF 2444

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLIT 424
                Y V ++E+  PG  + ++ A+D D  E+ +L Y     N      I S     ++ 
Sbjct: 2445 EKSTYIVYISENNEPGASIYSIQASDKDSEENAKLVYSSITSNREENLRIDSDISELVLE 2504

Query: 425  VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
            +  PL+ + E  + + ++A D G   ++ TA+++I +TD N+  P+F    YT S+ E+ 
Sbjct: 2505 I--PLNRETESIHEIVLTAFDGGSPMQTGTALIRITVTDMNDNFPIFGQEVYTVSINENI 2562

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
            P+ +TVL VSA D D GIN+QITYS S+  S +A     + F IN +TG I T + LD E
Sbjct: 2563 PLNSTVLCVSANDKDQGINSQITYSFSA-TSKQA----SRSFSINSETGEIKTKENLDFE 2617

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
                Y ++V A+DGG        +++I+V D NDN PVF Q++Y  NI E+  + ++V Q
Sbjct: 2618 KTKNYEISVQAKDGGGLVSHAKINIQITVTDFNDNFPVFTQEVYKVNIHENIPIHSTVLQ 2677

Query: 603  VGATDADVGLNGRIHYELDPKDREE-GSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
            V A+D D G+N +I Y            F I+P SG I T   +D E    +D+   A D
Sbjct: 2678 VNASDKDEGINAQITYSFGTTATNVLRIFAINPKSGEITTKGNVDFEETKYYDISVQAQD 2737

Query: 662  G--GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
            G  G+P  SS   + + I DIND+PP FE      Y++EN+  G +I  I+A D D   N
Sbjct: 2738 GDKGSPTLSSLKTIRLDILDINDNPPKFEKSNYVAYVTENNQPGASIYSIQAIDEDTEEN 2797

Query: 720  AVVHYSI--KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWN 776
              V YSI       +N+         +  E+ T  ++D+E   K Y++ + A     L +
Sbjct: 2798 GKVVYSIFTNNTTSANNVHRIFSINPNNGEITTKGNVDFEEV-KYYDISVEAQDGGSLVS 2856

Query: 777  DVRVEIL-VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILS 833
              +V I  V+D+NDN P  +    +    ++  P      + A D D  +  K+ Y I +
Sbjct: 2857 HSKVLIQNVSDINDNPPKFEKSNYVAYVTENNQPGSSIFSIKAIDKDTEENGKVVYSISN 2916

Query: 834  G----NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889
                 ++ + I +N  TG +T    L+        + ++ +DG N ++    L    +T+
Sbjct: 2917 NTVEFSSVSYISINPVTGFVTNQTSLDRETQSNHELILTASDGGNPVQTGTTLIKITVTD 2976



 Score =  420 bits (1034), Expect = e-115
 Identities = 286/881 (32%), Positives = 445/881 (50%), Gaps = 61/881 (6%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I V D ND+ PVF  + Y+ S+ E     +TVLT+ ATD+D G NA++ Y+    + + 
Sbjct: 923  RIAVTDSNDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQIMYSFSKTSGNN 982

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            L+                 +F I+  SG + T+ + + E    Y + V A D  SP    
Sbjct: 983  LHTS---------------MFSINYTSGEIKTKQNFNFEAKKFYEISVYAKDYGSP---S 1024

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVT-----DNPVIAKIKATDADVGAN 184
            LS  A++ + I D NDN P+    + + SVD    +         +I K+ A DAD G N
Sbjct: 1025 LSCNASLTIRITDQNDNVPKILYPS-SESVDSSFEMVPVASEQGALITKVVAVDADSGHN 1083

Query: 185  SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
            + + Y ++ G+    FSI   +G++   ++LD E+V  Y + I+A D GSP  SN   + 
Sbjct: 1084 AWLSYHVVQGSEPSLFSISQNTGEIRTSRSLDREKVPWYNITIQATDRGSPHLSNIKLIK 1143

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
            ++I DVNDNAP F  S +   ++EN   G SI R+QA D D G NA+L+Y +      G+
Sbjct: 1144 LDISDVNDNAPVFTKSSYVAYIAENNLAGASIYRIQASDIDAGDNAKLSYHVVQ----GS 1199

Query: 305  VDLPITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
                 +I   +G + TS + LDRETQ+ ++L++TA+DGG+P R+ TA             
Sbjct: 1200 EPSLFSISQNTGEIRTSQKPLDRETQSIHELILTASDGGNPLRTGTALIRIIVTDSNDNL 1259

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRF-SITSQNG- 419
              F    Y+V ++E+ P  + V+ LTATD DE    ++ Y I+  +    + S+ + N  
Sbjct: 1260 PVFTQEVYKVSISENAPINSSVIILTATDKDEGTNAQITYSISKTSENNFYTSVFNINPV 1319

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTAS 477
             G IT+         R  ++T +A+D G   R+ TA++++ +TDAN+  PVF    Y  S
Sbjct: 1320 MGEITIKVSTSSSYYR--IITTTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVS 1377

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            + E+ PI +TVL V+A+D D G NAQITYS S             +  +N     +   +
Sbjct: 1378 ISENTPINSTVLRVNASDMDEGTNAQITYSFS-------------RTSVNSLHAKLVLER 1424

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
             LDRE  + + L +TA DGG P  + T  + + V D NDN PVF Q++Y  +I E+  + 
Sbjct: 1425 PLDREIKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISENTPIN 1484

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREE---GSFVIDPASGVIRTNKALDRESVATHD 654
            ++V +V A+D D G N +I Y              F I+P SG I+T + LDRE+   H+
Sbjct: 1485 STVLRVNASDMDEGTNAQITYSFSRTSENSLHASMFSINPTSGEIKTKRPLDRETKNIHE 1544

Query: 655  LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
            L   A DGGTP ++ T ++ + + D ND+ PVF  +     ISEN+PI +T+  + A D 
Sbjct: 1545 LLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISENTPINSTVLRVNASDM 1604

Query: 715  DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---S 771
            DEG NA + YS      ++  +          E+ T   LD E+ +  +EL++ A+   +
Sbjct: 1605 DEGTNAQITYSFSRTSVNSLHASMFSINPTSGEITTKKPLDREA-QTSHELILTASDGGN 1663

Query: 772  PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRI 831
            P       ++I+VTD NDN PV  +  +   +  +   VG    V   +A    K+ Y I
Sbjct: 1664 PVRTGTALIQIIVTDANDNLPVFTEV-LYTVSISENTAVGSV--VLCVNASSNAKITYSI 1720

Query: 832  LSGNNAN-LILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
               N  +    +N  TG +      +    K   ME+   D
Sbjct: 1721 SETNTMSPYFSINIETGVLYAQQSFDYEQHKQFEMEIMAKD 1761



 Score =  410 bits (1009), Expect = e-112
 Identities = 286/906 (31%), Positives = 448/906 (49%), Gaps = 73/906 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I V D ND+ PVF    Y+AS+ E +   TTVL + ATD+D G NA++ Y+  +     
Sbjct: 820  KITVTDVNDNVPVFTQAVYKASISENSPVNTTVLYVNATDKDEGINAQIVYSFSVS---- 875

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                             +  F ID +SG L  +  LDRE    + +++ A+D  +PV   
Sbjct: 876  -----------------EKYFSIDLQSGMLYVKKPLDRETQTIHELILTASDGGNPVR-- 916

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             S TA I + + D NDN P F+++ Y VS+ E+I +  N  +  + ATD D G N+ I Y
Sbjct: 917  -SGTALIRIAVTDSNDNLPVFTQEVYKVSISENIPI--NSTVLTVNATDRDEGTNAQIMY 973

Query: 190  AI--IGGNT--QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
            +     GN      FSI+  SG++   +  ++E  + Y + + A+D GSPS S    L I
Sbjct: 974  SFSKTSGNNLHTSMFSINYTSGEIKTKQNFNFEAKKFYEISVYAKDYGSPSLSCNASLTI 1033

Query: 246  NIRDVNDNAPR--FYTSLFQESVSENVPI----GYSIVRVQAYDADEGVNAELTYTMTDK 299
             I D NDN P+  + +S   +S  E VP+    G  I +V A DAD G NA L+Y +   
Sbjct: 1034 RITDQNDNVPKILYPSSESVDSSFEMVPVASEQGALITKVVAVDADSGHNAWLSYHVVQ- 1092

Query: 300  DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
               G+     +I   +G + TS  LDRE    Y + + ATD G P  S            
Sbjct: 1093 ---GSEPSLFSISQNTGEIRTSRSLDREKVPWYNITIQATDRGSPHLSNIKLIKLDISDV 1149

Query: 360  XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRGRFSITSQ 417
                  F    Y   +AE+   G  +  + A+D D  DN +L Y +  G+    FSI SQ
Sbjct: 1150 NDNAPVFTKSSYVAYIAENNLAGASIYRIQASDIDAGDNAKLSYHVVQGSEPSLFSI-SQ 1208

Query: 418  NGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYT 475
            N   + T  +PLD + +  + L ++A+D G   R+ TA+++I +TD+N+  PVF    Y 
Sbjct: 1209 NTGEIRTSQKPLDRETQSIHELILTASDGGNPLRTGTALIRIIVTDSNDNLPVFTQEVYK 1268

Query: 476  ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
             S+ E+API ++V++++ATD D G NAQITYS+S    N     +   F INP  G IT 
Sbjct: 1269 VSISENAPINSSVIILTATDKDEGTNAQITYSISKTSENN---FYTSVFNINPVMGEIT- 1324

Query: 536  NKLLDRETMSGY--LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593
               +   T S Y  ++T TA DGG P  + T  + + V D NDN PVF Q++Y  +I E+
Sbjct: 1325 ---IKVSTSSSYYRIITTTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISEN 1381

Query: 594  ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653
              + ++V +V A+D D G N +I Y             ++     +   + LDRE    H
Sbjct: 1382 TPINSTVLRVNASDMDEGTNAQITYSFSRTS-------VNSLHAKLVLERPLDREIKNIH 1434

Query: 654  DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713
            +L   A DGGTP ++ T ++ + + D ND+ PVF  +     ISEN+PI +T+  + A D
Sbjct: 1435 ELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISENTPINSTVLRVNASD 1494

Query: 714  PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA--- 770
             DEG NA + YS     +++  +          E+ T   LD E+ +  +EL++ A+   
Sbjct: 1495 MDEGTNAQITYSFSRTSENSLHASMFSINPTSGEIKTKRPLDRET-KNIHELLLTASDGG 1553

Query: 771  SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPAYDAD------V 823
            +P       + ++VTD NDN PV    ++   +  +  P+     RV A D D      +
Sbjct: 1554 TPVRTGTALIRVIVTDANDNTPVFTQ-EVYKVSISENTPINSTVLRVNASDMDEGTNAQI 1612

Query: 824  TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLS 883
            T       ++  +A++  +N T+G +T    L+        + ++ +DG N ++    L 
Sbjct: 1613 TYSFSRTSVNSLHASMFSINPTSGEITTKKPLDREAQTSHELILTASDGGNPVRTGTALI 1672

Query: 884  VRLITE 889
              ++T+
Sbjct: 1673 QIIVTD 1678



 Score =  402 bits (991), Expect = e-110
 Identities = 293/973 (30%), Positives = 475/973 (48%), Gaps = 55/973 (5%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++++ D ND+ PVF    Y   + E    G ++ T+ ATD D G NA++ Y+I       
Sbjct: 1899 KLDISDVNDNPPVFRKSLYTTYLPENNLPGASIYTVHATDVDSGDNAKLIYSIS-----N 1953

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             N ED                   GR   ++T  +LDRE+   Y + + ATD+  P   +
Sbjct: 1954 ANTEDFPLISST------------GRFYRIVTTNNLDRERTPFYNITILATDRGYP---Q 1998

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             +S   I V I D NDN P F + TY   + E+       +I  + A D DVG N+ + Y
Sbjct: 1999 RTSKKMIGVEISDVNDNAPLFIKPTYDAFLPENN--LPGALIYSLHAKDLDVGDNAKVTY 2056

Query: 190  AIIGGNTQMQFSIDS-LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            +I+  NT   FS+ S  S ++     LD E    + LV+ A DGG+P ++ T  + I + 
Sbjct: 2057 SIL--NTNTDFSVSSYFSINIETGAPLDRETESIHELVLTAFDGGNPVQTGTAIIKIIVS 2114

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            D NDNAP F   ++  S++EN+P+  +I+RV A D DEG N+++TY       +      
Sbjct: 2115 DFNDNAPIFTQEVYTVSLNENIPVNSTILRVSANDKDEGSNSQITYYFAAS--SKQAMNT 2172

Query: 309  ITIDPRSGWVYTSGQLDRE-TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
              ID  SG V T   LD E  + ++Q+ + A D G P  +++                F 
Sbjct: 2173 FIIDSISGEVKTKENLDFEKIEREFQIQIMAKDHGSPSLNSSTNLRICIVDFNDNLPVFS 2232

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITV 425
               Y+V + E+ P  + ++ ++A D DE  ++++ Y  +  + +   +    +  G I  
Sbjct: 2233 QEVYKVSINENIPINSTILYVSANDKDEGINSQIRYYFSTSSKQILNTFIINSISGAIMT 2292

Query: 426  AQPLDFKQERRYVLTVSATDS-GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
             + LDF++ + Y ++V A D   G + TA+++I +TDAN+  P+F    Y  S+ E+ P+
Sbjct: 2293 KENLDFEKTKLYEISVQANDQYTGETGTALIRITVTDANDNFPMFSQEIYKVSINENMPL 2352

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
             +TVL VSA+D D GIN+Q+TYS SS  S +A       F INPQ+G I T+  LDRE  
Sbjct: 2353 NSTVLYVSASDKDEGINSQLTYSFSS-ASKQAT----NAFAINPQSGEIVTSSTLDREMK 2407

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
            S Y +T+ A D G P LS    + + V D+NDN PVF++  Y   I E+   G S+  + 
Sbjct: 2408 SHYDITIQATDKGSPPLSSRKTIRLDVSDINDNAPVFEKSTYIVYISENNEPGASIYSIQ 2467

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            A+D D   N ++ Y     +REE +  ID     +     L+RE+ + H++   A DGG+
Sbjct: 2468 ASDKDSEENAKLVYSSITSNREE-NLRIDSDISELVLEIPLNRETESIHEIVLTAFDGGS 2526

Query: 665  PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
            P Q+ T ++ I + D+ND+ P+F  +  T  I+EN P+ +T+  + A+D D+G N+ + Y
Sbjct: 2527 PMQTGTALIRITVTDMNDNFPIFGQEVYTVSINENIPLNSTVLCVSANDKDQGINSQITY 2586

Query: 725  SIKGGDD--SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVR 779
            S        S SFS+ +  G    E+ T  +LD+E   K YE+ ++A           + 
Sbjct: 2587 SFSATSKQASRSFSINSETG----EIKTKENLDFEK-TKNYEISVQAKDGGGLVSHAKIN 2641

Query: 780  VEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPAYDADVTDKLQYRILSGNNAN 838
            ++I VTD NDN PV    ++   N  +  P+     +V A D D     Q     G  A 
Sbjct: 2642 IQITVTDFNDNFPVFTQ-EVYKVNIHENIPIHSTVLQVNASDKDEGINAQITYSFGTTAT 2700

Query: 839  LIL----LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQL-SVRLITEEMLL 893
             +L    +N  +G +T    ++    K   + V   DG      +  L ++RL   ++  
Sbjct: 2701 NVLRIFAINPKSGEITTKGNVDFEETKYYDISVQAQDGDKGSPTLSSLKTIRLDILDIND 2760

Query: 894  NSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKEN-IYIFSVQDDTDVTGNILNVSFS 952
            N      ++  A    +   G  I  + AI    +EN   ++S+  +   + N ++  FS
Sbjct: 2761 NPPKFEKSNYVAYVTENNQPGASIYSIQAIDEDTEENGKVVYSIFTNNTTSANNVHRIFS 2820

Query: 953  ARRPDAEVGVAGD 965
                + E+   G+
Sbjct: 2821 INPNNGEITTKGN 2833



 Score =  395 bits (973), Expect = e-108
 Identities = 256/800 (32%), Positives = 409/800 (51%), Gaps = 50/800 (6%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I ++D ND+ PVF  + Y+ S+ E     +T+L + A D+D G N+++ Y     +   
Sbjct: 2218 RICIVDFNDNLPVFSQEVYKVSINENIPINSTILYVSANDKDEGINSQIRYYFSTSSKQI 2277

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            LN                  F I+  SGA++T+ +LD EK   Y + V+A DQ +  +  
Sbjct: 2278 LN-----------------TFIINSISGAIMTKENLDFEKTKLYEISVQANDQYTGET-- 2318

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
               TA I + + D NDN+P FS++ Y VS++E++ +  N  +  + A+D D G NS + Y
Sbjct: 2319 --GTALIRITVTDANDNFPMFSQEIYKVSINENMPL--NSTVLYVSASDKDEGINSQLTY 2374

Query: 190  AIIGGNTQM--QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            +    + Q    F+I+  SG++    TLD E    Y + I+A D GSP  S+   + +++
Sbjct: 2375 SFSSASKQATNAFAINPQSGEIVTSSTLDREMKSHYDITIQATDKGSPPLSSRKTIRLDV 2434

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
             D+NDNAP F  S +   +SEN   G SI  +QA D D   NA+L Y+      T N + 
Sbjct: 2435 SDINDNAPVFEKSTYIVYISENNEPGASIYSIQASDKDSEENAKLVYS----SITSNREE 2490

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
             + ID     +     L+RET++ +++++TA DGG P ++ TA               F 
Sbjct: 2491 NLRIDSDISELVLEIPLNRETESIHEIVLTAFDGGSPMQTGTALIRITVTDMNDNFPIFG 2550

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITV 425
               Y V + E+ P  + V+ ++A D D+  ++++ Y  +  + +   S +  +  G I  
Sbjct: 2551 QEVYTVSINENIPLNSTVLCVSANDKDQGINSQITYSFSATSKQASRSFSINSETGEIKT 2610

Query: 426  AQPLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAP 483
             + LDF++ + Y ++V A D GG    A   +QI +TD N+  PVF    Y  ++ E+ P
Sbjct: 2611 KENLDFEKTKNYEISVQAKDGGGLVSHAKINIQITVTDFNDNFPVFTQEVYKVNIHENIP 2670

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
            I +TVL V+A+D D GINAQITYS  +  +N       + F INP++G ITT   +D E 
Sbjct: 2671 IHSTVLQVNASDKDEGINAQITYSFGTTATNVL-----RIFAINPKSGEITTKGNVDFEE 2725

Query: 544  MSGYLLTVTARDG--GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
               Y ++V A+DG  G P+LS    + + ++D+NDN P F++  Y A + E+   G S+ 
Sbjct: 2726 TKYYDISVQAQDGDKGSPTLSSLKTIRLDILDINDNPPKFEKSNYVAYVTENNQPGASIY 2785

Query: 602  QVGATDADVGLNGRIHYELDPKDREEGS-----FVIDPASGVIRTNKALDRESVATHDLK 656
             + A D D   NG++ Y +   +    +     F I+P +G I T   +D E V  +D+ 
Sbjct: 2786 SIQAIDEDTEENGKVVYSIFTNNTTSANNVHRIFSINPNNGEITTKGNVDFEEVKYYDIS 2845

Query: 657  AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
              A DGG+    S V++   + DIND+PP FE      Y++EN+  G++I  I+A D D 
Sbjct: 2846 VEAQDGGSLVSHSKVLIQ-NVSDINDNPPKFEKSNYVAYVTENNQPGSSIFSIKAIDKDT 2904

Query: 717  GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPP 773
              N  V YSI       S             +     LD E+ +  +EL++ A+   +P 
Sbjct: 2905 EENGKVVYSISNNTVEFSSVSYISINPVTGFVTNQTSLDRET-QSNHELILTASDGGNPV 2963

Query: 774  LWNDVRVEILVTDVNDNAPV 793
                  ++I VTDVNDN PV
Sbjct: 2964 QTGTTLIKITVTDVNDNFPV 2983



 Score =  386 bits (949), Expect = e-105
 Identities = 233/688 (33%), Positives = 364/688 (52%), Gaps = 43/688 (6%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVE-YTIELVTAD 68
            +I V D ND+ PVF  + Y+  V E ++ GT V  ++  D D G+N EV  + + +V   
Sbjct: 2971 KITVTDVNDNFPVFTQEVYKTPVSEDSTLGTVVALIEGHDLDSGENGEVICHIVGMVPFK 3030

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
             L+                      G    ++T ++LDREK + Y + ++ATD+ SP   
Sbjct: 3031 LLSSS--------------------GNFYKIVTTSTLDREKNSHYNITIQATDKGSPP-- 3068

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             LS   TI ++I D NDN P F + TYT  +    S     ++ K+ A DAD G N+ + 
Sbjct: 3069 -LSFQKTIRLDISDINDNAPVFEKSTYTYEM-VPFSSEQGTLVTKVVAVDADSGHNAWLS 3126

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            Y  +  +    F ID  +G++    +LD E   ++ L++ A DGG+P ++ TT + I + 
Sbjct: 3127 YHFLQDSETSHFIIDQYTGEIRTSTSLDRETQSNHELILTASDGGNPVQTGTTLIKITVT 3186

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            D NDN P F   +++ ++ EN+P+  +I  V A D DEG+NA++TY+ +    + NV   
Sbjct: 3187 DFNDNLPEFTQEVYKVNIHENIPLNSTIFHVNASDKDEGINAQITYSFSST--SNNVLRI 3244

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
             +I P++G + T G LD+E  + Y + + ATD G PP S   T              F  
Sbjct: 3245 FSIHPKNGAIKTKGTLDKEKNSHYNITIQATDKGSPPLSYQKTIRLDVLDINDNSPVFEK 3304

Query: 369  GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSIT--SQNG-RGLI 423
             QY   + E+  PG  + ++ A D D  E+ +L Y I   NT    SI+  S N   G+I
Sbjct: 3305 SQYIAYVPENNQPGASIFSIQAIDKDTEENGKLLYSIITRNTEEMPSISYISINPVTGVI 3364

Query: 424  TVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFED 481
               +  D++Q+R + + + A D+G    + +A+V+I +TD N+  PVF    Y  ++ E+
Sbjct: 3365 YAQRSFDYEQDREFKIQIMAKDNGSPPLNSSAIVRITVTDFNDNFPVFTQEVYKVNIHEN 3424

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
             PI +TVL V+A+D D GINAQITYS S+  +N       + F INPQ G I     LDR
Sbjct: 3425 IPINSTVLHVNASDKDEGINAQITYSFSTTSANVL-----RMFYINPQNGEIKIKGTLDR 3479

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
            E  S Y +T+ A D G P LS    + + V+D+NDN PVF++  Y A + E+   G S+ 
Sbjct: 3480 ERSSHYNITIQATDKGSPPLSSWKTIALEVLDINDNSPVFEKSTYIAYVPENNQPGASIY 3539

Query: 602  QVGATDADVGLNGRIHYELDPKDREE---GSFV-IDPASGVIRTNKALDRESVATHDLKA 657
             + A D D   NG++ Y +   + EE    S++ I+P +GVI   ++ D E     +++ 
Sbjct: 3540 SIQAIDKDTEENGKLFYSIITSNTEELSSTSYISINPVTGVIYAQRSFDYEQDREFEIQI 3599

Query: 658  VAIDGGTPPQSSTVIVHIKIEDINDSPP 685
            +A D G+PP +S+ IV I + D ND+ P
Sbjct: 3600 IAKDNGSPPLNSSTIVRICVVDQNDNSP 3627



 Score =  385 bits (947), Expect = e-104
 Identities = 273/886 (30%), Positives = 435/886 (49%), Gaps = 53/886 (5%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            I+ QI V D ND+ PVF  + Y+ ++ E     +TVL + A+D+D G NA++ Y+     
Sbjct: 2640 INIQITVTDFNDNFPVFTQEVYKVNIHENIPIHSTVLQVNASDKDEGINAQITYSFGTTA 2699

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
             + L                  +F I+ +SG + T+ ++D E+   Y + V+A D     
Sbjct: 2700 TNVLR-----------------IFAINPKSGEITTKGNVDFEETKYYDISVQAQD-GDKG 2741

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
            S  LSS  TI ++I+D NDN P+F +  Y   V E+        I  I+A D D   N  
Sbjct: 2742 SPTLSSLKTIRLDILDINDNPPKFEKSNYVAYVTENNQ--PGASIYSIQAIDEDTEENGK 2799

Query: 187  IRYAIIGGNTQMQ------FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240
            + Y+I   NT         FSI+  +G+++    +D+E+V+ Y + + AQDGGS   S++
Sbjct: 2800 VVYSIFTNNTTSANNVHRIFSINPNNGEITTKGNVDFEEVKYYDISVEAQDGGS-LVSHS 2858

Query: 241  TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
              L+ N+ D+NDN P+F  S +   V+EN   G SI  ++A D D   N ++ Y++++  
Sbjct: 2859 KVLIQNVSDINDNPPKFEKSNYVAYVTENNQPGSSIFSIKAIDKDTEENGKVVYSISNNT 2918

Query: 301  YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
               +    I+I+P +G+V     LDRETQ+ ++L++TA+DGG+P ++ T           
Sbjct: 2919 VEFSSVSYISINPVTGFVTNQTSLDRETQSNHELILTASDGGNPVQTGTTLIKITVTDVN 2978

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQN 418
                 F    Y+  ++ED   GT V  +   D D  E+  +   I G      F + S +
Sbjct: 2979 DNFPVFTQEVYKTPVSEDSTLGTVVALIEGHDLDSGENGEVICHIVG---MVPFKLLSSS 3035

Query: 419  GRGL-ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYT 475
            G    I     LD ++   Y +T+ ATD G    S    ++++I+D N+ APVFE + YT
Sbjct: 3036 GNFYKIVTTSTLDREKNSHYNITIQATDKGSPPLSFQKTIRLDISDINDNAPVFEKSTYT 3095

Query: 476  ASVFE-DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
              +    +  GT V  V A D+D G NA ++Y     + +   +H    F+I+  TG I 
Sbjct: 3096 YEMVPFSSEQGTLVTKVVAVDADSGHNAWLSYHF---LQDSETSH----FIIDQYTGEIR 3148

Query: 535  TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
            T+  LDRET S + L +TA DGG P  + TT ++I+V D NDN P F Q++Y  NI E+ 
Sbjct: 3149 TSTSLDRETQSNHELILTASDGGNPVQTGTTLIKITVTDFNDNLPEFTQEVYKVNIHENI 3208

Query: 595  LVGTSVSQVGATDADVGLNGRIHYELDPKDREE-GSFVIDPASGVIRTNKALDRESVATH 653
             + +++  V A+D D G+N +I Y            F I P +G I+T   LD+E  + +
Sbjct: 3209 PLNSTIFHVNASDKDEGINAQITYSFSSTSNNVLRIFSIHPKNGAIKTKGTLDKEKNSHY 3268

Query: 654  DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713
            ++   A D G+PP S    + + + DIND+ PVFE      Y+ EN+  G +I  I+A D
Sbjct: 3269 NITIQATDKGSPPLSYQKTIRLDVLDINDNSPVFEKSQYIAYVPENNQPGASIFSIQAID 3328

Query: 714  PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV-TMVDLDYESPRK-KYELVIR-AA 770
             D   N  + YSI   +     S+     +    ++      DYE  R+ K +++ +   
Sbjct: 3329 KDTEENGKLLYSIITRNTEEMPSISYISINPVTGVIYAQRSFDYEQDREFKIQIMAKDNG 3388

Query: 771  SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPAYDAD--VTDKL 827
            SPPL +   V I VTD NDN PV    ++   N  +  P+      V A D D  +  ++
Sbjct: 3389 SPPLNSSAIVRITVTDFNDNFPVFTQ-EVYKVNIHENIPINSTVLHVNASDKDEGINAQI 3447

Query: 828  QYRI--LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
             Y     S N   +  +N   G + +   L+        + +  TD
Sbjct: 3448 TYSFSTTSANVLRMFYINPQNGEIKIKGTLDRERSSHYNITIQATD 3493



 Score =  383 bits (942), Expect = e-104
 Identities = 267/898 (29%), Positives = 440/898 (48%), Gaps = 52/898 (5%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I V D ND+ P+F  + Y+ S+ E     +TVL + A+D+D G N+++ Y+    +   
Sbjct: 2324 RITVTDANDNFPMFSQEIYKVSINENMPLNSTVLYVSASDKDEGINSQLTYSFSSASKQA 2383

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             N                  F I+ +SG ++T ++LDRE  + Y + ++ATD+ SP    
Sbjct: 2384 TN-----------------AFAINPQSGEIVTSSTLDREMKSHYDITIQATDKGSPP--- 2423

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            LSS  TI +++ D NDN P F + TY V + E+        I  I+A+D D   N+ + Y
Sbjct: 2424 LSSRKTIRLDVSDINDNAPVFEKSTYIVYISENNE--PGASIYSIQASDKDSEENAKLVY 2481

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            + I  N +    IDS   ++ L   L+ E    + +V+ A DGGSP ++ T  + I + D
Sbjct: 2482 SSITSNREENLRIDSDISELVLEIPLNRETESIHEIVLTAFDGGSPMQTGTALIRITVTD 2541

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            +NDN P F   ++  S++EN+P+  +++ V A D D+G+N+++TY+ +    +       
Sbjct: 2542 MNDNFPIFGQEVYTVSINENIPLNSTVLCVSANDKDQGINSQITYSFSAT--SKQASRSF 2599

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            +I+  +G + T   LD E    Y++ V A DGG     A                 F   
Sbjct: 2600 SINSETGEIKTKENLDFEKTKNYEISVQAKDGGGLVSHAKINIQITVTDFNDNFPVFTQE 2659

Query: 370  QYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI--TGGNTRGRFSITSQNGRGLITV 425
             Y+V + E+ P  + V+ + A+D DE  + ++ Y    T  N    F+I  ++G   IT 
Sbjct: 2660 VYKVNIHENIPIHSTVLQVNASDKDEGINAQITYSFGTTATNVLRIFAINPKSGE--ITT 2717

Query: 426  AQPLDFKQERRYVLTVSATDSGGRSDTAM----VQINITDANNYAPVFENAPYTASVFED 481
               +DF++ + Y ++V A D    S T      ++++I D N+  P FE + Y A V E+
Sbjct: 2718 KGNVDFEETKYYDISVQAQDGDKGSPTLSSLKTIRLDILDINDNPPKFEKSNYVAYVTEN 2777

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
               G ++  + A D D   N ++ YS+ +  +  A   H + F INP  G ITT   +D 
Sbjct: 2778 NQPGASIYSIQAIDEDTEENGKVVYSIFTNNTTSANNVH-RIFSINPNNGEITTKGNVDF 2836

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEI-SVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
            E +  Y ++V A+DGG  SL   + V I +V D+NDN P F++  Y A + E+   G+S+
Sbjct: 2837 EEVKYYDISVEAQDGG--SLVSHSKVLIQNVSDINDNPPKFEKSNYVAYVTENNQPGSSI 2894

Query: 601  SQVGATDADVGLNGRIHYELDPKDREEGS---FVIDPASGVIRTNKALDRESVATHDLKA 657
              + A D D   NG++ Y +     E  S     I+P +G +    +LDRE+ + H+L  
Sbjct: 2895 FSIKAIDKDTEENGKVVYSISNNTVEFSSVSYISINPVTGFVTNQTSLDRETQSNHELIL 2954

Query: 658  VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
             A DGG P Q+ T ++ I + D+ND+ PVF  +     +SE+S +GT +  I  HD D G
Sbjct: 2955 TASDGGNPVQTGTTLIKITVTDVNDNFPVFTQEVYKTPVSEDSTLGTVVALIEGHDLDSG 3014

Query: 718  PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPL 774
             N  V   I G      F L +  G+   ++VT   LD E     Y + I+A    SPPL
Sbjct: 3015 ENGEVICHIVG---MVPFKLLSSSGNFY-KIVTTSTLDREK-NSHYNITIQATDKGSPPL 3069

Query: 775  WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDK--LQYRI 831
                 + + ++D+NDNAPV +     +         G    +V A DAD      L Y  
Sbjct: 3070 SFQKTIRLDISDINDNAPVFEKSTYTYEMVPFSSEQGTLVTKVVAVDADSGHNAWLSYHF 3129

Query: 832  LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889
            L  +  +  ++++ TG +  S  L+        + ++ +DG N ++    L    +T+
Sbjct: 3130 LQDSETSHFIIDQYTGEIRTSTSLDRETQSNHELILTASDGGNPVQTGTTLIKITVTD 3187



 Score =  380 bits (934), Expect = e-103
 Identities = 256/804 (31%), Positives = 408/804 (50%), Gaps = 62/804 (7%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +++V D ND++PVFE   Y   + E    G ++ +++A+D+D  +NA++ Y+     + T
Sbjct: 2431 RLDVSDINDNAPVFEKSTYIVYISENNEPGASIYSIQASDKDSEENAKLVYS-----SIT 2485

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             N E+                RID     L+    L+RE  + + +++ A D  SP+   
Sbjct: 2486 SNREEN--------------LRIDSDISELVLEIPLNRETESIHEIVLTAFDGGSPMQ-- 2529

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             + TA I + + D NDN+P F ++ YTVS++E+I +  N  +  + A D D G NS I Y
Sbjct: 2530 -TGTALIRITVTDMNDNFPIFGQEVYTVSINENIPL--NSTVLCVSANDKDQGINSQITY 2586

Query: 190  AIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            +    + Q    FSI+S +G++   + LD+E+ ++Y + ++A+DGG         + I +
Sbjct: 2587 SFSATSKQASRSFSINSETGEIKTKENLDFEKTKNYEISVQAKDGGGLVSHAKINIQITV 2646

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
             D NDN P F   +++ ++ EN+PI  ++++V A D DEG+NA++TY+        NV  
Sbjct: 2647 TDFNDNFPVFTQEVYKVNIHENIPIHSTVLQVNASDKDEGINAQITYSFGTT--ATNVLR 2704

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG--GDPPRSATATXXXXXXXXXXXXXX 365
               I+P+SG + T G +D E    Y + V A DG  G P  S+  T              
Sbjct: 2705 IFAINPKSGEITTKGNVDFEETKYYDISVQAQDGDKGSPTLSSLKTIRLDILDINDNPPK 2764

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGR------FSITSQ 417
            F    Y   + E+  PG  + ++ A D D  E+ ++ Y I   NT         FSI   
Sbjct: 2765 FEKSNYVAYVTENNQPGASIYSIQAIDEDTEENGKVVYSIFTNNTTSANNVHRIFSINPN 2824

Query: 418  NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQI-NITDANNYAPVFENAPYTA 476
            NG   IT    +DF++ + Y ++V A D G     + V I N++D N+  P FE + Y A
Sbjct: 2825 NGE--ITTKGNVDFEEVKYYDISVEAQDGGSLVSHSKVLIQNVSDINDNPPKFEKSNYVA 2882

Query: 477  SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV-INPQTGAITT 535
             V E+   G+++  + A D D   N ++ YS    ISN  V      ++ INP TG +T 
Sbjct: 2883 YVTENNQPGSSIFSIKAIDKDTEENGKVVYS----ISNNTVEFSSVSYISINPVTGFVTN 2938

Query: 536  NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
               LDRET S + L +TA DGG P  + TT ++I+V DVNDN PVF Q++Y   + ED+ 
Sbjct: 2939 QTSLDRETQSNHELILTASDGGNPVQTGTTLIKITVTDVNDNFPVFTQEVYKTPVSEDST 2998

Query: 596  VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG---VIRTNKALDRESVAT 652
            +GT V+ +   D D G NG +   +         F +  +SG    I T   LDRE  + 
Sbjct: 2999 LGTVVALIEGHDLDSGENGEVICHIVGM----VPFKLLSSSGNFYKIVTTSTLDREKNSH 3054

Query: 653  HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF-YISENSPIGTTIGEIRA 711
            +++   A D G+PP S    + + I DIND+ PVFE    T+  +  +S  GT + ++ A
Sbjct: 3055 YNITIQATDKGSPPLSFQKTIRLDISDINDNAPVFEKSTYTYEMVPFSSEQGTLVTKVVA 3114

Query: 712  HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA- 770
             D D G NA + Y      +++ F ++   G    E+ T   LD E+ +  +EL++ A+ 
Sbjct: 3115 VDADSGHNAWLSYHFLQDSETSHFIIDQYTG----EIRTSTSLDRET-QSNHELILTASD 3169

Query: 771  --SPPLWNDVRVEILVTDVNDNAP 792
              +P       ++I VTD NDN P
Sbjct: 3170 GGNPVQTGTTLIKITVTDFNDNLP 3193



 Score =  380 bits (934), Expect = e-103
 Identities = 269/868 (30%), Positives = 423/868 (48%), Gaps = 70/868 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++++LD ND+ P FE   Y A V E    G ++ +++A D+D  +N +V Y+I   T +T
Sbjct: 2752 RLDILDINDNPPKFEKSNYVAYVTENNQPGASIYSIQAIDEDTEENGKVVYSI--FTNNT 2809

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             +  +           V  +F I+  +G + T+ ++D E+V  Y + V+A D  S VS  
Sbjct: 2810 TSANN-----------VHRIFSINPNNGEITTKGNVDFEEVKYYDISVEAQDGGSLVSH- 2857

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
               +  +  N+ D NDN P+F +  Y   V E+     +  I  IKA D D   N  + Y
Sbjct: 2858 ---SKVLIQNVSDINDNPPKFEKSNYVAYVTENNQPGSS--IFSIKAIDKDTEENGKVVY 2912

Query: 190  AIIGGNTQMQ----FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
            +I     +       SI+ ++G V+   +LD E   ++ L++ A DGG+P ++ TT + I
Sbjct: 2913 SISNNTVEFSSVSYISINPVTGFVTNQTSLDRETQSNHELILTASDGGNPVQTGTTLIKI 2972

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
             + DVNDN P F   +++  VSE+  +G  +  ++ +D D G N E+   +         
Sbjct: 2973 TVTDVNDNFPVFTQEVYKTPVSEDSTLGTVVALIEGHDLDSGENGEVICHIVGM------ 3026

Query: 306  DLPITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
             +P  +   SG  Y   T+  LDRE  + Y + + ATD G PP S   T           
Sbjct: 3027 -VPFKLLSSSGNFYKIVTTSTLDREKNSHYNITIQATDKGSPPLSFQKTIRLDISDINDN 3085

Query: 363  XXXFMPGQYEVELAE-DEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNG 419
               F    Y  E+       GT V  + A DAD  +   L Y     +    F I    G
Sbjct: 3086 APVFEKSTYTYEMVPFSSEQGTLVTKVVAVDADSGHNAWLSYHFLQDSETSHFIIDQYTG 3145

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTAS 477
               I  +  LD + +  + L ++A+D G   ++ T +++I +TD N+  P F    Y  +
Sbjct: 3146 E--IRTSTSLDRETQSNHELILTASDGGNPVQTGTTLIKITVTDFNDNLPEFTQEVYKVN 3203

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            + E+ P+ +T+  V+A+D D GINAQITYS SS  +N       + F I+P+ GAI T  
Sbjct: 3204 IHENIPLNSTIFHVNASDKDEGINAQITYSFSSTSNNVL-----RIFSIHPKNGAIKTKG 3258

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
             LD+E  S Y +T+ A D G P LS    + + V+D+NDN PVF++  Y A + E+   G
Sbjct: 3259 TLDKEKNSHYNITIQATDKGSPPLSYQKTIRLDVLDINDNSPVFEKSQYIAYVPENNQPG 3318

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREEG---SFV-IDPASGVIRTNKALDRESVATH 653
             S+  + A D D   NG++ Y +  ++ EE    S++ I+P +GVI   ++ D E     
Sbjct: 3319 ASIFSIQAIDKDTEENGKLLYSIITRNTEEMPSISYISINPVTGVIYAQRSFDYEQDREF 3378

Query: 654  DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713
             ++ +A D G+PP +S+ IV I + D ND+ PVF  +     I EN PI +T+  + A D
Sbjct: 3379 KIQIMAKDNGSPPLNSSAIVRITVTDFNDNFPVFTQEVYKVNIHENIPINSTVLHVNASD 3438

Query: 714  PDEGPNAVVHYSIK--GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA-- 769
             DEG NA + YS      +    F +  + G    E+     LD E     Y + I+A  
Sbjct: 3439 KDEGINAQITYSFSTTSANVLRMFYINPQNG----EIKIKGTLDRER-SSHYNITIQATD 3493

Query: 770  -ASPPL--WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD- 825
              SPPL  W  + +E+L  D+NDN+PV +    I    ++  P      + A D D  + 
Sbjct: 3494 KGSPPLSSWKTIALEVL--DINDNSPVFEKSTYIAYVPENNQPGASIYSIQAIDKDTEEN 3551

Query: 826  -KLQYRILSGNNANL-----ILLNETTG 847
             KL Y I++ N   L     I +N  TG
Sbjct: 3552 GKLFYSIITSNTEELSSTSYISINPVTG 3579



 Score =  379 bits (933), Expect = e-103
 Identities = 260/863 (30%), Positives = 420/863 (48%), Gaps = 61/863 (7%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I V D ND+ P+F  + Y  S+ E     +TVL + A D+D G N+++ Y+    +   
Sbjct: 2536 RITVTDMNDNFPIFGQEVYTVSINENIPLNSTVLCVSANDKDQGINSQITYSFSATSKQA 2595

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                                F I+  +G + T+ +LD EK   Y + V+A D    VS  
Sbjct: 2596 SRS-----------------FSINSETGEIKTKENLDFEKTKNYEISVQAKDGGGLVSH- 2637

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
              +   I + + D NDN+P F+++ Y V++ E+I +  +  + ++ A+D D G N+ I Y
Sbjct: 2638 --AKINIQITVTDFNDNFPVFTQEVYKVNIHENIPI--HSTVLQVNASDKDEGINAQITY 2693

Query: 190  AI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG--GSPSRSNTTQLLI 245
            +      N    F+I+  SG+++    +D+E+ + Y + ++AQDG  GSP+ S+   + +
Sbjct: 2694 SFGTTATNVLRIFAINPKSGEITTKGNVDFEETKYYDISVQAQDGDKGSPTLSSLKTIRL 2753

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-- 303
            +I D+NDN P+F  S +   V+EN   G SI  +QA D D   N ++ Y++   + T   
Sbjct: 2754 DILDINDNPPKFEKSNYVAYVTENNQPGASIYSIQAIDEDTEENGKVVYSIFTNNTTSAN 2813

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
            NV    +I+P +G + T G +D E    Y + V A DGG    S +              
Sbjct: 2814 NVHRIFSINPNNGEITTKGNVDFEEVKYYDISVEAQDGGSLV-SHSKVLIQNVSDINDNP 2872

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTR-GRFSITSQNG- 419
              F    Y   + E+  PG+ + ++ A D D  E+ ++ Y I+         S  S N  
Sbjct: 2873 PKFEKSNYVAYVTENNQPGSSIFSIKAIDKDTEENGKVVYSISNNTVEFSSVSYISINPV 2932

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTAS 477
             G +T    LD + +  + L ++A+D G   ++ T +++I +TD N+  PVF    Y   
Sbjct: 2933 TGFVTNQTSLDRETQSNHELILTASDGGNPVQTGTTLIKITVTDVNDNFPVFTQEVYKTP 2992

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            V ED+ +GT V ++   D D G N ++   +   +  + ++     +        I T  
Sbjct: 2993 VSEDSTLGTVVALIEGHDLDSGENGEVICHIVGMVPFKLLSSSGNFY-------KIVTTS 3045

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME-DALV 596
             LDRE  S Y +T+ A D G P LS    + + + D+NDN PVF++  YT  ++   +  
Sbjct: 3046 TLDREKNSHYNITIQATDKGSPPLSFQKTIRLDISDINDNAPVFEKSTYTYEMVPFSSEQ 3105

Query: 597  GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
            GT V++V A DAD G N  + Y    +D E   F+ID  +G IRT+ +LDRE+ + H+L 
Sbjct: 3106 GTLVTKVVAVDADSGHNAWLSYHF-LQDSETSHFIIDQYTGEIRTSTSLDRETQSNHELI 3164

Query: 657  AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
              A DGG P Q+ T ++ I + D ND+ P F  +     I EN P+ +TI  + A D DE
Sbjct: 3165 LTASDGGNPVQTGTTLIKITVTDFNDNLPEFTQEVYKVNIHENIPLNSTIFHVNASDKDE 3224

Query: 717  GPNAVVHYSIKGGDDS--NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---AS 771
            G NA + YS     ++    FS+  + G+ K    T   LD E     Y + I+A    S
Sbjct: 3225 GINAQITYSFSSTSNNVLRIFSIHPKNGAIK----TKGTLDKEK-NSHYNITIQATDKGS 3279

Query: 772  PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQY 829
            PPL     + + V D+NDN+PV +  Q I    ++  P      + A D D  +  KL Y
Sbjct: 3280 PPLSYQKTIRLDVLDINDNSPVFEKSQYIAYVPENNQPGASIFSIQAIDKDTEENGKLLY 3339

Query: 830  RILSGNNANL-----ILLNETTG 847
             I++ N   +     I +N  TG
Sbjct: 3340 SIITRNTEEMPSISYISINPVTG 3362



 Score =  377 bits (927), Expect = e-102
 Identities = 277/910 (30%), Positives = 459/910 (50%), Gaps = 68/910 (7%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            QI V D ND+ PVF    Y  S+ E  + G+ VL + A+      NA++ Y+I     +T
Sbjct: 1673 QIIVTDANDNLPVFTEVLYTVSISENTAVGSVVLCVNASS-----NAKITYSIS--ETNT 1725

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            ++P                 F I+  +G L  + S D E+  ++ + + A D   P S  
Sbjct: 1726 MSP----------------YFSINIETGVLYAQQSFDYEQHKQFEMEIMAKDNGFP-SMT 1768

Query: 130  LSSTATIH----VNIIDDNDNYPQFSEKTYTVSVDEDISVTD----NPVIAKI-KATDAD 180
             ++T  IH    V + D NDN P F+E+ YTVS+ E+  V      N    KI +A+D D
Sbjct: 1769 SNTTLLIHIIDRVVVTDANDNAPVFTEEVYTVSISENAPVNAIVLCNDNAPKIVQASDLD 1828

Query: 181  VGANSAIRYAIIGGNTQM-----QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP 235
             G NS + Y++   NT+       FSI+  +G +   ++ DYEQ + + + ++A+D G P
Sbjct: 1829 TGENSKVIYSVFNTNTEAFPVSSYFSINIETGVLYAQRSFDYEQHKEFAMHVQAKDNGYP 1888

Query: 236  S-RSNTTQLL-INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293
            S +S+  + + ++I DVNDN P F  SL+   + EN   G SI  V A D D G NA+L 
Sbjct: 1889 SHQSHKWKFIKLDISDVNDNPPVFRKSLYTTYLPENNLPGASIYTVHATDVDSGDNAKLI 1948

Query: 294  YTMTDKDYTGNVDLP-ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352
            Y++++       D P I+   R   + T+  LDRE    Y + + ATD G P R++    
Sbjct: 1949 YSISN---ANTEDFPLISSTGRFYRIVTTNNLDRERTPFYNITILATDRGYPQRTSKKMI 2005

Query: 353  XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRF 412
                         F+   Y+  L E+  PG  + +L A D D  +      +  NT   F
Sbjct: 2006 GVEISDVNDNAPLFIKPTYDAFLPENNLPGALIYSLHAKDLDVGDNAKVTYSILNTNTDF 2065

Query: 413  SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFE 470
            S++S     + T A PLD + E  + L ++A D G   ++ TA+++I ++D N+ AP+F 
Sbjct: 2066 SVSSYFSINIETGA-PLDRETESIHELVLTAFDGGNPVQTGTAIIKIIVSDFNDNAPIFT 2124

Query: 471  NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
               YT S+ E+ P+ +T+L VSA D D G N+QITY  ++  S +A+      F+I+  +
Sbjct: 2125 QEVYTVSLNENIPVNSTILRVSANDKDEGSNSQITYYFAAS-SKQAM----NTFIIDSIS 2179

Query: 531  GAITTNKLLDRETMS-GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589
            G + T + LD E +   + + + A+D G PSL+ +T++ I +VD NDN PVF Q++Y  +
Sbjct: 2180 GEVKTKENLDFEKIEREFQIQIMAKDHGSPSLNSSTNLRICIVDFNDNLPVFSQEVYKVS 2239

Query: 590  IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNKALDRE 648
            I E+  + +++  V A D D G+N +I Y      ++   +F+I+  SG I T + LD E
Sbjct: 2240 INENIPINSTILYVSANDKDEGINSQIRYYFSTSSKQILNTFIINSISGAIMTKENLDFE 2299

Query: 649  SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
                +++   A D  T  ++ T ++ I + D ND+ P+F  +     I+EN P+ +T+  
Sbjct: 2300 KTKLYEISVQANDQYT-GETGTALIRITVTDANDNFPMFSQEIYKVSINENMPLNSTVLY 2358

Query: 709  IRAHDPDEGPNAVVHYSIKGGDD--SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV 766
            + A D DEG N+ + YS        +N+F++  + G    E+VT   LD E  +  Y++ 
Sbjct: 2359 VSASDKDEGINSQLTYSFSSASKQATNAFAINPQSG----EIVTSSTLDREM-KSHYDIT 2413

Query: 767  IRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV 823
            I+A    SPPL +   + + V+D+NDNAPV +    I    ++  P      + A D D 
Sbjct: 2414 IQATDKGSPPLSSRKTIRLDVSDINDNAPVFEKSTYIVYISENNEPGASIYSIQASDKDS 2473

Query: 824  TD--KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQ 881
             +  KL Y  ++ N    + ++     + L   LN     +  + ++  DG + ++    
Sbjct: 2474 EENAKLVYSSITSNREENLRIDSDISELVLEIPLNRETESIHEIVLTAFDGGSPMQTGTA 2533

Query: 882  LSVRLITEEM 891
            L +R+   +M
Sbjct: 2534 L-IRITVTDM 2542



 Score =  376 bits (925), Expect = e-102
 Identities = 270/918 (29%), Positives = 435/918 (47%), Gaps = 65/918 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT- 69
            I V D ND+ PVF  Q Y+ S+ E A   +TV  + ATD+D G N  + Y+      +  
Sbjct: 569  IIVTDYNDNVPVFTQQVYKISISESAPINSTVTVVTATDKDDGTNGHITYSFSRTAENAF 628

Query: 70   ------LNPEDAXXXXXXXXXXVQDVFR-------IDGRSGALLTRASLDREKVARYTVL 116
                  +NP +             + +        I   +G + T      + + ++ V+
Sbjct: 629  HTQMFNINPANGEIKTKVDADSGHNSWLSYHFIQIISQHTGEIRTSRMFQEKDILKHKVV 688

Query: 117  VKATDQASPVSDRLSSTATIHVNIIDDNDNY-PQF--------SEKTYTVSVDEDISVTD 167
            +   D   P    LS+T T+ + + D   +  PQ         S K Y VSV E+  +  
Sbjct: 689  IMVKDNGDP---SLSATVTLSLAVGDHFQHVVPQINNEFNDGPSSKVYKVSVSENAPINS 745

Query: 168  NPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVI 227
              +I  + ATD D G N+ I Y+I   +    ++ID  +G++ L   LD E   ++ L +
Sbjct: 746  TVII--LTATDKDEGTNAKITYSISKTSKNNFYTIDLDNGNLVLENPLDREMQSTHELTL 803

Query: 228  RAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG 287
             A DGG+P R+ T  + I + DVNDN P F  ++++ S+SEN P+  +++ V A D DEG
Sbjct: 804  TAFDGGTPVRTGTALIKITVTDVNDNVPVFTQAVYKASISENSPVNTTVLYVNATDKDEG 863

Query: 288  VNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRS 347
            +NA++ Y+ +  +   ++DL      +SG +Y    LDRETQ  ++L++TA+DGG+P RS
Sbjct: 864  INAQIVYSFSVSEKYFSIDL------QSGMLYVKKPLDRETQTIHELILTASDGGNPVRS 917

Query: 348  ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH----YEI 403
             TA               F    Y+V ++E+ P  + V+T+ ATD DE         +  
Sbjct: 918  GTALIRIAVTDSNDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQIMYSFSK 977

Query: 404  TGGNT--RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINI 459
            T GN      FSI   +G   I   Q  +F+ ++ Y ++V A D G    S  A + I I
Sbjct: 978  TSGNNLHTSMFSINYTSGE--IKTKQNFNFEAKKFYEISVYAKDYGSPSLSCNASLTIRI 1035

Query: 460  TDANNYAP--VFENAPYTASVFEDAPI----GTTVLVVSATDSDVGINAQITYSLSSEIS 513
            TD N+  P  ++ ++    S FE  P+    G  +  V A D+D G NA ++Y +     
Sbjct: 1036 TDQNDNVPKILYPSSESVDSSFEMVPVASEQGALITKVVAVDADSGHNAWLSYHV----- 1090

Query: 514  NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
                      F I+  TG I T++ LDRE +  Y +T+ A D G P LS+   +++ + D
Sbjct: 1091 --VQGSEPSLFSISQNTGEIRTSRSLDREKVPWYNITIQATDRGSPHLSNIKLIKLDISD 1148

Query: 574  VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633
            VNDN PVF +  Y A I E+ L G S+ ++ A+D D G N ++ Y +  +  E   F I 
Sbjct: 1149 VNDNAPVFTKSSYVAYIAENNLAGASIYRIQASDIDAGDNAKLSYHV-VQGSEPSLFSIS 1207

Query: 634  PASGVIRTN-KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692
              +G IRT+ K LDRE+ + H+L   A DGG P ++ T ++ I + D ND+ PVF  +  
Sbjct: 1208 QNTGEIRTSQKPLDRETQSIHELILTASDGGNPLRTGTALIRIIVTDSNDNLPVFTQEVY 1267

Query: 693  TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752
               ISEN+PI +++  + A D DEG NA + YSI    ++N ++          E+   V
Sbjct: 1268 KVSISENAPINSSVIILTATDKDEGTNAQITYSISKTSENNFYTSVFNINPVMGEITIKV 1327

Query: 753  DLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-G 811
                   R          +P       + ++VTD NDN PV    ++   +  +  P+  
Sbjct: 1328 STSSSYYRIITTTASDGGTPVRTGTALIRVIVTDANDNTPVFTQ-EVYKVSISENTPINS 1386

Query: 812  PFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
               RV A D D     Q        +    +N     + L   L+  +  +  + ++ +D
Sbjct: 1387 TVLRVNASDMDEGTNAQITYSFSRTS----VNSLHAKLVLERPLDREIKNIHELLLTASD 1442

Query: 872  GVNEIKAMMQLSVRLITE 889
            G   ++    L   ++T+
Sbjct: 1443 GGTPVRTGTALIRVIVTD 1460



 Score =  366 bits (900), Expect = 5e-99
 Identities = 268/878 (30%), Positives = 440/878 (50%), Gaps = 97/878 (11%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++++ D ND++PVF    Y A + E   +G ++  ++A+D D G NA++ Y +   +  +
Sbjct: 1143 KLDISDVNDNAPVFTKSSYVAYIAENNLAGASIYRIQASDIDAGDNAKLSYHVVQGSEPS 1202

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLT-RASLDREKVARYTVLVKATDQASPVSD 128
            L                   F I   +G + T +  LDRE  + + +++ A+D  +P+  
Sbjct: 1203 L-------------------FSISQNTGEIRTSQKPLDRETQSIHELILTASDGGNPLR- 1242

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
              + TA I + + D NDN P F+++ Y VS+ E+  +  + +I  + ATD D G N+ I 
Sbjct: 1243 --TGTALIRIIVTDSNDNLPVFTQEVYKVSISENAPINSSVII--LTATDKDEGTNAQIT 1298

Query: 189  YAIIGGNTQ----MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
            Y+I   +        F+I+ + G++++  +      R   +   A DGG+P R+ T  + 
Sbjct: 1299 YSISKTSENNFYTSVFNINPVMGEITIKVSTSSSYYRI--ITTTASDGGTPVRTGTALIR 1356

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
            + + D NDN P F   +++ S+SEN PI  +++RV A D DEG NA++TY+ + +    +
Sbjct: 1357 VIVTDANDNTPVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFS-RTSVNS 1415

Query: 305  VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
            +   + ++           LDRE +  ++LL+TA+DGG P R+ TA              
Sbjct: 1416 LHAKLVLER---------PLDREIKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTP 1466

Query: 365  XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH----YEITGGNT--RGRFSITSQN 418
             F    Y+V ++E+ P  + V+ + A+D DE         +  T  N+     FSI   +
Sbjct: 1467 VFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSENSLHASMFSINPTS 1526

Query: 419  GRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTA 476
            G   I   +PLD + +  + L ++A+D G   R+ TA++++ +TDAN+  PVF    Y  
Sbjct: 1527 GE--IKTKRPLDRETKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKV 1584

Query: 477  SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
            S+ E+ PI +TVL V+A+D D G NAQITYS S    N     H   F INP +G ITT 
Sbjct: 1585 SISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVNSL---HASMFSINPTSGEITTK 1641

Query: 537  KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
            K LDRE  + + L +TA DGG P  + T  ++I V D NDN PVF + LYT +I E+  V
Sbjct: 1642 KPLDREAQTSHELILTASDGGNPVRTGTALIQIIVTDANDNLPVFTEVLYTVSISENTAV 1701

Query: 597  GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
            G+ V  V A+      N +I Y +   +     F I+  +GV+   ++ D E     +++
Sbjct: 1702 GSVVLCVNASS-----NAKITYSISETNTMSPYFSINIETGVLYAQQSFDYEQHKQFEME 1756

Query: 657  AVAIDGGTPPQSS--TVIVHI----KIEDINDSPPVFESDCLTFYISENSPIGTTI---- 706
             +A D G P  +S  T+++HI     + D ND+ PVF  +  T  ISEN+P+   +    
Sbjct: 1757 IMAKDNGFPSMTSNTTLLIHIIDRVVVTDANDNAPVFTEEVYTVSISENAPVNAIVLCND 1816

Query: 707  ---GEIRAHDPDEGPNAVVHYSIKGGDD-----SNSFSLETRQGSDKAELVTMVDLDYES 758
                 ++A D D G N+ V YS+   +      S+ FS+    G     L      DYE 
Sbjct: 1817 NAPKIVQASDLDTGENSKVIYSVFNTNTEAFPVSSYFSINIETG----VLYAQRSFDYEQ 1872

Query: 759  PRKKYELVIRAA-------SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY--KDCFP 809
              K++ + ++A            W  ++++I  +DVNDN PV +  + ++  Y  ++  P
Sbjct: 1873 -HKEFAMHVQAKDNGYPSHQSHKWKFIKLDI--SDVNDNPPVFR--KSLYTTYLPENNLP 1927

Query: 810  VGPFGRVPAYDADVTD--KLQYRILSGNNANLILLNET 845
                  V A D D  D  KL Y I + N  +  L++ T
Sbjct: 1928 GASIYTVHATDVDSGDNAKLIYSISNANTEDFPLISST 1965



 Score =  363 bits (893), Expect = 4e-98
 Identities = 251/798 (31%), Positives = 393/798 (49%), Gaps = 47/798 (5%)

Query: 12   NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71
            NV D ND+ P FE   Y A V E    G+++ ++KA D+D  +N +V Y+I   T +  +
Sbjct: 2864 NVSDINDNPPKFEKSNYVAYVTENNQPGSSIFSIKAIDKDTEENGKVVYSISNNTVEFSS 2923

Query: 72   PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131
                                I+  +G +  + SLDRE  + + +++ A+D  +PV    +
Sbjct: 2924 VS---------------YISINPVTGFVTNQTSLDRETQSNHELILTASDGGNPVQ---T 2965

Query: 132  STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191
             T  I + + D NDN+P F+++ Y   V ED ++    V+A I+  D D G N  +   I
Sbjct: 2966 GTTLIKITVTDVNDNFPVFTQEVYKTPVSEDSTL--GTVVALIEGHDLDSGENGEVICHI 3023

Query: 192  IGGNTQMQFSIDSLSGD---VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            +G    + F + S SG+   +    TLD E+   Y + I+A D GSP  S    + ++I 
Sbjct: 3024 VG---MVPFKLLSSSGNFYKIVTTSTLDREKNSHYNITIQATDKGSPPLSFQKTIRLDIS 3080

Query: 249  DVNDNAPRFYTSLFQ-ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            D+NDNAP F  S +  E V  +   G  + +V A DAD G NA L+Y       T +   
Sbjct: 3081 DINDNAPVFEKSTYTYEMVPFSSEQGTLVTKVVAVDADSGHNAWLSYHFLQDSETSH--- 3137

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
               ID  +G + TS  LDRETQ+ ++L++TA+DGG+P ++ T                F 
Sbjct: 3138 -FIIDQYTGEIRTSTSLDRETQSNHELILTASDGGNPVQTGTTLIKITVTDFNDNLPEFT 3196

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI--TGGNTRGRFSITSQNGRGLI 423
               Y+V + E+ P  + +  + A+D DE  + ++ Y    T  N    FSI  +NG   I
Sbjct: 3197 QEVYKVNIHENIPLNSTIFHVNASDKDEGINAQITYSFSSTSNNVLRIFSIHPKNGA--I 3254

Query: 424  TVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFED 481
                 LD ++   Y +T+ ATD G    S    +++++ D N+ +PVFE + Y A V E+
Sbjct: 3255 KTKGTLDKEKNSHYNITIQATDKGSPPLSYQKTIRLDVLDINDNSPVFEKSQYIAYVPEN 3314

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
               G ++  + A D D   N ++ YS+ +  + E  +       INP TG I   +  D 
Sbjct: 3315 NQPGASIFSIQAIDKDTEENGKLLYSIITRNTEEMPSI--SYISINPVTGVIYAQRSFDY 3372

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
            E    + + + A+D G P L+ +  V I+V D NDN PVF Q++Y  NI E+  + ++V 
Sbjct: 3373 EQDREFKIQIMAKDNGSPPLNSSAIVRITVTDFNDNFPVFTQEVYKVNIHENIPINSTVL 3432

Query: 602  QVGATDADVGLNGRIHYELDPKDREE-GSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
             V A+D D G+N +I Y            F I+P +G I+    LDRE  + +++   A 
Sbjct: 3433 HVNASDKDEGINAQITYSFSTTSANVLRMFYINPQNGEIKIKGTLDRERSSHYNITIQAT 3492

Query: 661  DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
            D G+PP SS   + +++ DIND+ PVFE      Y+ EN+  G +I  I+A D D   N 
Sbjct: 3493 DKGSPPLSSWKTIALEVLDINDNSPVFEKSTYIAYVPENNQPGASIYSIQAIDKDTEENG 3552

Query: 721  VVHYSIKGGDDSNSFSLETRQGSDKAELV-TMVDLDYESPRKKYELVIRA---ASPPLWN 776
             + YSI   +     S      +    ++      DYE  R+ +E+ I A    SPPL +
Sbjct: 3553 KLFYSIITSNTEELSSTSYISINPVTGVIYAQRSFDYEQDRE-FEIQIIAKDNGSPPLNS 3611

Query: 777  DVRVEILVTDVNDNAPVM 794
               V I V D NDN+P +
Sbjct: 3612 STIVRICVVDQNDNSPTV 3629



 Score =  358 bits (881), Expect = 1e-96
 Identities = 278/906 (30%), Positives = 440/906 (48%), Gaps = 64/906 (7%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVL-------TLKATDQDIGKNAEVE 59
            I  ++ V D ND++PVF  + Y  S+ E A     VL        ++A+D D G+N++V 
Sbjct: 1777 IIDRVVVTDANDNAPVFTEEVYTVSISENAPVNAIVLCNDNAPKIVQASDLDTGENSKVI 1836

Query: 60   YTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKA 119
            Y++        N E            V   F I+  +G L  + S D E+   + + V+A
Sbjct: 1837 YSV-----FNTNTE---------AFPVSSYFSINIETGVLYAQRSFDYEQHKEFAMHVQA 1882

Query: 120  TDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA 179
             D   P S +      I ++I D NDN P F +  YT  + E  +      I  + ATD 
Sbjct: 1883 KDNGYP-SHQSHKWKFIKLDISDVNDNPPVFRKSLYTTYLPE--NNLPGASIYTVHATDV 1939

Query: 180  DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPS 236
            D G N+ + Y+I   NT+  F + S +G    + T   LD E+   Y + I A D G P 
Sbjct: 1940 DSGDNAKLIYSISNANTE-DFPLISSTGRFYRIVTTNNLDRERTPFYNITILATDRGYPQ 1998

Query: 237  RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
            R++   + + I DVNDNAP F    +   + EN   G  I  + A D D G NA++TY++
Sbjct: 1999 RTSKKMIGVEISDVNDNAPLFIKPTYDAFLPENNLPGALIYSLHAKDLDVGDNAKVTYSI 2058

Query: 297  TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
             + +   +V    +I+     + T   LDRET++ ++L++TA DGG+P ++ TA      
Sbjct: 2059 LNTNTDFSVSSYFSIN-----IETGAPLDRETESIHELVLTAFDGGNPVQTGTAIIKIIV 2113

Query: 357  XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSI 414
                     F    Y V L E+ P  + ++ ++A D DE  ++++ Y     + +   + 
Sbjct: 2114 SDFNDNAPIFTQEVYTVSLNENIPVNSTILRVSANDKDEGSNSQITYYFAASSKQAMNTF 2173

Query: 415  TSQNGRGLITVAQPLDF-KQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFEN 471
               +  G +   + LDF K ER + + + A D G  S   +  ++I I D N+  PVF  
Sbjct: 2174 IIDSISGEVKTKENLDFEKIEREFQIQIMAKDHGSPSLNSSTNLRICIVDFNDNLPVFSQ 2233

Query: 472  APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
              Y  S+ E+ PI +T+L VSA D D GIN+QI Y  S+  S++ + +    F+IN  +G
Sbjct: 2234 EVYKVSINENIPINSTILYVSANDKDEGINSQIRYYFST--SSKQILN---TFIINSISG 2288

Query: 532  AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
            AI T + LD E    Y ++V A D      + T  + I+V D NDN P+F Q++Y  +I 
Sbjct: 2289 AIMTKENLDFEKTKLYEISVQAND-QYTGETGTALIRITVTDANDNFPMFSQEIYKVSIN 2347

Query: 592  EDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNKALDRESV 650
            E+  + ++V  V A+D D G+N ++ Y      ++   +F I+P SG I T+  LDRE  
Sbjct: 2348 ENMPLNSTVLYVSASDKDEGINSQLTYSFSSASKQATNAFAINPQSGEIVTSSTLDREMK 2407

Query: 651  ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710
            + +D+   A D G+PP SS   + + + DIND+ PVFE      YISEN+  G +I  I+
Sbjct: 2408 SHYDITIQATDKGSPPLSSRKTIRLDVSDINDNAPVFEKSTYIVYISENNEPGASIYSIQ 2467

Query: 711  AHDPDEGPNA-VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
            A D D   NA +V+ SI    + N      R  SD +ELV  + L+ E+    +E+V+ A
Sbjct: 2468 ASDKDSEENAKLVYSSITSNREEN-----LRIDSDISELVLEIPLNRET-ESIHEIVLTA 2521

Query: 770  ---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR-VPAYDAD--V 823
                SP       + I VTD+NDN P+    ++   +  +  P+      V A D D  +
Sbjct: 2522 FDGGSPMQTGTALIRITVTDMNDNFPIFGQ-EVYTVSINENIPLNSTVLCVSANDKDQGI 2580

Query: 824  TDKLQYRI--LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG---VNEIKA 878
              ++ Y     S   +    +N  TG +     L+    K   + V   DG   V+  K 
Sbjct: 2581 NSQITYSFSATSKQASRSFSINSETGEIKTKENLDFEKTKNYEISVQAKDGGGLVSHAKI 2640

Query: 879  MMQLSV 884
             +Q++V
Sbjct: 2641 NIQITV 2646



 Score =  356 bits (875), Expect = 6e-96
 Identities = 271/886 (30%), Positives = 427/886 (48%), Gaps = 73/886 (8%)

Query: 28   YEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQ 87
            Y+ SV E A   +TV+ L ATD+D G NA++ Y+I   + +                   
Sbjct: 733  YKVSVSENAPINSTVIILTATDKDEGTNAKITYSISKTSKNNF----------------- 775

Query: 88   DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
              + ID  +G L+    LDRE  + + + + A D  +PV    + TA I + + D NDN 
Sbjct: 776  --YTIDLDNGNLVLENPLDREMQSTHELTLTAFDGGTPVR---TGTALIKITVTDVNDNV 830

Query: 148  PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
            P F++  Y  S+ E+  V  N  +  + ATD D G N+ I Y+     ++  FSID  SG
Sbjct: 831  PVFTQAVYKASISENSPV--NTTVLYVNATDKDEGINAQIVYSF--SVSEKYFSIDLQSG 886

Query: 208  DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
             + + K LD E    + L++ A DGG+P RS T  + I + D NDN P F   +++ S+S
Sbjct: 887  MLYVKKPLDRETQTIHELILTASDGGNPVRSGTALIRIAVTDSNDNLPVFTQEVYKVSIS 946

Query: 268  ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
            EN+PI  +++ V A D DEG NA++ Y+ +            +I+  SG + T    + E
Sbjct: 947  ENIPINSTVLTVNATDRDEGTNAQIMYSFSKTSGNNLHTSMFSINYTSGEIKTKQNFNFE 1006

Query: 328  TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM-PGQYEVELAEDEPP----- 381
             +  Y++ V A D G P  S  A+               + P    V+ + +  P     
Sbjct: 1007 AKKFYEISVYAKDYGSPSLSCNASLTIRITDQNDNVPKILYPSSESVDSSFEMVPVASEQ 1066

Query: 382  GTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL 439
            G  +  + A DAD  +   L Y +  G+    FSI SQN  G I  ++ LD ++   Y +
Sbjct: 1067 GALITKVVAVDADSGHNAWLSYHVVQGSEPSLFSI-SQN-TGEIRTSRSLDREKVPWYNI 1124

Query: 440  TVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497
            T+ ATD G    S+  +++++I+D N+ APVF  + Y A + E+   G ++  + A+D D
Sbjct: 1125 TIQATDRGSPHLSNIKLIKLDISDVNDNAPVFTKSSYVAYIAENNLAGASIYRIQASDID 1184

Query: 498  VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKLLDRETMSGYLLTVTARDG 556
             G NA+++Y +               F I+  TG I T+ K LDRET S + L +TA DG
Sbjct: 1185 AGDNAKLSYHV-------VQGSEPSLFSISQNTGEIRTSQKPLDRETQSIHELILTASDG 1237

Query: 557  GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616
            G P  + T  + I V D NDN PVF Q++Y  +I E+A + +SV  + ATD D G N +I
Sbjct: 1238 GNPLRTGTALIRIIVTDSNDNLPVFTQEVYKVSISENAPINSSVIILTATDKDEGTNAQI 1297

Query: 617  HYELDPKDREE---GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673
             Y +            F I+P  G I     +   S     +   A DGGTP ++ T ++
Sbjct: 1298 TYSISKTSENNFYTSVFNINPVMGEITIK--VSTSSSYYRIITTTASDGGTPVRTGTALI 1355

Query: 674  HIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN 733
             + + D ND+ PVF  +     ISEN+PI +T+  + A D DEG NA + Y         
Sbjct: 1356 RVIVTDANDNTPVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITY--------- 1406

Query: 734  SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDN 790
            SFS  T   S  A+LV    LD E  +  +EL++ A+   +P       + ++VTD NDN
Sbjct: 1407 SFS-RTSVNSLHAKLVLERPLDREI-KNIHELLLTASDGGTPVRTGTALIRVIVTDANDN 1464

Query: 791  APVMKDFQIIFNNYKDCFPV-GPFGRVPAYDADVTDKLQ----YRILSGN--NANLILLN 843
             PV    ++   +  +  P+     RV A D D     Q    +   S N  +A++  +N
Sbjct: 1465 TPVFTQ-EVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSENSLHASMFSIN 1523

Query: 844  ETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889
             T+G +     L+     +  + ++ +DG   ++    L   ++T+
Sbjct: 1524 PTSGEIKTKRPLDRETKNIHELLLTASDGGTPVRTGTALIRVIVTD 1569



 Score =  255 bits (625), Expect = 1e-65
 Identities = 198/648 (30%), Positives = 305/648 (47%), Gaps = 45/648 (6%)

Query: 137 HVNII--DDNDNYPQFSEKTYTVSVDEDISVT--DNPVIAKIKAT--DADVGANSAIRYA 190
           H  II  D NDN P F+++ Y V + E  S +  +   +A  + T    D          
Sbjct: 18  HTRIIISDANDNIPVFTKEVYKVRITESSSSSLFEMVPLASEQGTLITKDTITLEISEST 77

Query: 191 IIGGNTQMQFSIDSLSGDVSLVK-TLDYEQVRSYRLVIRAQDGGSPS--------RSNTT 241
           + G +  +Q + D   G  S+ +  L   Q  S +  IR      P         R   T
Sbjct: 78  LPGTHLVLQTAEDPDIGINSVQRYILSDNQFLSLKEKIRTDGSKIPELVLEKYLDRETQT 137

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY----TMT 297
            + I I D NDN P F   +++  +SEN P+  +++ V A D DEG+NA++TY    T  
Sbjct: 138 LIKIIISDANDNIPEFSKEVYKVKMSENTPVNTTVLSVDATDKDEGLNAQITYSFSKTSD 197

Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357
           ++ +TG  D    I+P SG + T   LD E+   Y++ + A DGG     A         
Sbjct: 198 NQLHTGTFD----INPTSGKITTKRDLDFESVQSYEIAIEAMDGGG--FVAQTKVLIEII 251

Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSIT 415
                            + ED  PGT +  +   D D   +  +  +I G      F I 
Sbjct: 252 DENDNAPEISIASLSAPIPEDSMPGTVIALIKVHDQDTGRNGEVDCQILGA---APFQIV 308

Query: 416 SQNGRGL-ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENA 472
           S + R   I  A  LD ++   Y +T+ ATD G    S T  ++I ITD N++ P+F   
Sbjct: 309 SSSSRYYRIITASFLDREKVPWYNITILATDKGSPELSSTKSIKIAITDVNDHIPMFTQE 368

Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
            Y  S+ E  PI TTVL V+ATD D G+NAQITYSL    S +++A     F INP +G 
Sbjct: 369 VYKVSISESIPINTTVLQVNATDKDEGVNAQITYSL-IRTSGDSLA--SATFSINPASGE 425

Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592
           I T + L+ E    Y ++V A+D     +     ++IS  DVNDN P+F +  Y A + E
Sbjct: 426 IKTKRNLNFEVQKHYEMSVEAKDKSY--IKKVIRLDIS--DVNDNPPLFLKSTYVAYLPE 481

Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREE----GSFVIDPASGVIRTNKALDRE 648
           + + G S+ ++ A+D D+G N ++ Y +   + E+      F I+  +GV+ + ++ D E
Sbjct: 482 NNIPGASIYKIQASDLDLGDNAKVIYSISNSNTEDFAVSSFFSINIETGVLYSQRSFDYE 541

Query: 649 SVATHDLKAVAIDGGTPPQS-STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
                 ++ +A DGG+PP S +  +  I + D ND+ PVF        ISE++PI +T+ 
Sbjct: 542 QHKVFQMEIMARDGGSPPLSNNATLFMIIVTDYNDNVPVFTQQVYKISISESAPINSTVT 601

Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755
            + A D D+G N  + YS     ++   +          E+ T VD D
Sbjct: 602 VVTATDKDDGTNGHITYSFSRTAENAFHTQMFNINPANGEIKTKVDAD 649



 Score =  250 bits (612), Expect = 4e-64
 Identities = 195/661 (29%), Positives = 307/661 (46%), Gaps = 37/661 (5%)

Query: 1   MSVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD--IGKNAEV 58
           +++  C H +I + D ND+ PVF  + Y+  + E +SS    +   A++Q   I K+   
Sbjct: 11  LALILCKHTRIIISDANDNIPVFTKEVYKVRITESSSSSLFEMVPLASEQGTLITKDTIT 70

Query: 59  EYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVK 118
               E     T                VQ     D +  +L  +   D  K+    VL K
Sbjct: 71  LEISESTLPGTHLVLQTAEDPDIGINSVQRYILSDNQFLSLKEKIRTDGSKIPE-LVLEK 129

Query: 119 ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178
             D+         +   I + I D NDN P+FS++ Y V + E+  V  N  +  + ATD
Sbjct: 130 YLDR--------ETQTLIKIIISDANDNIPEFSKEVYKVKMSENTPV--NTTVLSVDATD 179

Query: 179 ADVGANSAIRYAII-GGNTQMQ---FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS 234
            D G N+ I Y+     + Q+    F I+  SG ++  + LD+E V+SY + I A DGG 
Sbjct: 180 KDEGLNAQITYSFSKTSDNQLHTGTFDINPTSGKITTKRDLDFESVQSYEIAIEAMDGGG 239

Query: 235 PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294
                 T++LI I D NDNAP    +     + E+   G  I  ++ +D D G N E+  
Sbjct: 240 FVAQ--TKVLIEIIDENDNAPEISIASLSAPIPEDSMPGTVIALIKVHDQDTGRNGEV-- 295

Query: 295 TMTDKDYTGNVDLPI-TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353
              D    G     I +   R   + T+  LDRE    Y + + ATD G P  S+T +  
Sbjct: 296 ---DCQILGAAPFQIVSSSSRYYRIITASFLDREKVPWYNITILATDKGSPELSSTKSIK 352

Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI--TGGNTR 409
                       F    Y+V ++E  P  T V+ + ATD DE  + ++ Y +  T G++ 
Sbjct: 353 IAITDVNDHIPMFTQEVYKVSISESIPINTTVLQVNATDKDEGVNAQITYSLIRTSGDSL 412

Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVF 469
              + +     G I   + L+F+ ++ Y ++V A D        +++++I+D N+  P+F
Sbjct: 413 ASATFSINPASGEIKTKRNLNFEVQKHYEMSVEAKDKS--YIKKVIRLDISDVNDNPPLF 470

Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
             + Y A + E+   G ++  + A+D D+G NA++ YS+S+  SN         F IN +
Sbjct: 471 LKSTYVAYLPENNIPGASIYKIQASDLDLGDNAKVIYSISN--SNTEDFAVSSFFSINIE 528

Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLS-DTTDVEISVVDVNDNEPVFKQQLYTA 588
           TG + + +  D E    + + + ARDGG P LS + T   I V D NDN PVF QQ+Y  
Sbjct: 529 TGVLYSQRSFDYEQHKVFQMEIMARDGGSPPLSNNATLFMIIVTDYNDNVPVFTQQVYKI 588

Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR---EEGSFVIDPASGVIRTNKAL 645
           +I E A + ++V+ V ATD D G NG I Y              F I+PA+G I+T    
Sbjct: 589 SISESAPINSTVTVVTATDKDDGTNGHITYSFSRTAENAFHTQMFNINPANGEIKTKVDA 648

Query: 646 D 646
           D
Sbjct: 649 D 649



 Score =  215 bits (525), Expect = 1e-53
 Identities = 165/546 (30%), Positives = 260/546 (47%), Gaps = 56/546 (10%)

Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325
           +SE+   G  +V   A D D G+N+   Y ++D  +    +   T   +   +     LD
Sbjct: 73  ISESTLPGTHLVLQTAEDPDIGINSVQRYILSDNQFLSLKEKIRTDGSKIPELVLEKYLD 132

Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
           RETQ   +++++  +   P                     F    Y+V+++E+ P  T V
Sbjct: 133 RETQTLIKIIISDANDNIPE--------------------FSKEVYKVKMSENTPVNTTV 172

Query: 386 VTLTATDADE--DNRLHYEI--TGGNT--RGRFSITSQNGRGLITVAQPLDFKQERRYVL 439
           +++ ATD DE  + ++ Y    T  N    G F I   +G+  IT  + LDF+  + Y +
Sbjct: 173 LSVDATDKDEGLNAQITYSFSKTSDNQLHTGTFDINPTSGK--ITTKRDLDFESVQSYEI 230

Query: 440 TVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499
            + A D GG      V I I D N+ AP    A  +A + ED+  GT + ++   D D G
Sbjct: 231 AIEAMDGGGFVAQTKVLIEIIDENDNAPEISIASLSAPIPEDSMPGTVIALIKVHDQDTG 290

Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
            N ++   +      + V+   + +        I T   LDRE +  Y +T+ A D G P
Sbjct: 291 RNGEVDCQILGAAPFQIVSSSSRYY-------RIITASFLDREKVPWYNITILATDKGSP 343

Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619
            LS T  ++I++ DVND+ P+F Q++Y  +I E   + T+V QV ATD D G+N +I Y 
Sbjct: 344 ELSSTKSIKIAITDVNDHIPMFTQEVYKVSISESIPINTTVLQVNATDKDEGVNAQITYS 403

Query: 620 L---DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676
           L           +F I+PASG I+T + L+ E    +++   A D     +    ++ + 
Sbjct: 404 LIRTSGDSLASATFSINPASGEIKTKRNLNFEVQKHYEMSVEAKDKSYIKK----VIRLD 459

Query: 677 IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD----- 731
           I D+ND+PP+F       Y+ EN+  G +I +I+A D D G NA V YSI   +      
Sbjct: 460 ISDVNDNPPLFLKSTYVAYLPENNIPGASIYKIQASDLDLGDNAKVIYSISNSNTEDFAV 519

Query: 732 SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRV-EILVTDV 787
           S+ FS+    G     L +    DYE   K +++ I A    SPPL N+  +  I+VTD 
Sbjct: 520 SSFFSINIETG----VLYSQRSFDYEQ-HKVFQMEIMARDGGSPPLSNNATLFMIIVTDY 574

Query: 788 NDNAPV 793
           NDN PV
Sbjct: 575 NDNVPV 580



 Score =  204 bits (498), Expect = 3e-50
 Identities = 145/438 (33%), Positives = 218/438 (49%), Gaps = 29/438 (6%)

Query: 449 RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508
           R    +++I I+DAN+  P F    Y   + E+ P+ TTVL V ATD D G+NAQITYS 
Sbjct: 133 RETQTLIKIIISDANDNIPEFSKEVYKVKMSENTPVNTTVLSVDATDKDEGLNAQITYSF 192

Query: 509 SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568
           S    N+    H   F INP +G ITT + LD E++  Y + + A DGG       T V 
Sbjct: 193 SKTSDNQL---HTGTFDINPTSGKITTKRDLDFESVQSYEIAIEAMDGG--GFVAQTKVL 247

Query: 569 ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG 628
           I ++D NDN P       +A I ED++ GT ++ +   D D G NG    E+D +     
Sbjct: 248 IEIIDENDNAPEISIASLSAPIPEDSMPGTVIALIKVHDQDTGRNG----EVDCQILGAA 303

Query: 629 SF-VIDPASGVIR--TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685
            F ++  +S   R  T   LDRE V  +++  +A D G+P  SST  + I I D+ND  P
Sbjct: 304 PFQIVSSSSRYYRIITASFLDREKVPWYNITILATDKGSPELSSTKSIKIAITDVNDHIP 363

Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI--KGGDD--SNSFSLETRQ 741
           +F  +     ISE+ PI TT+ ++ A D DEG NA + YS+    GD   S +FS+    
Sbjct: 364 MFTQEVYKVSISESIPINTTVLQVNATDKDEGVNAQITYSLIRTSGDSLASATFSINPAS 423

Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801
           G    E+ T  +L++E  +K YE+ + A        V + + ++DVNDN P+      + 
Sbjct: 424 G----EIKTKRNLNFE-VQKHYEMSVEAKDKSYIKKV-IRLDISDVNDNPPLFLKSTYVA 477

Query: 802 NNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGNN-----ANLILLNETTGSMTLSPQ 854
              ++  P     ++ A D D+ D  K+ Y I + N      ++   +N  TG +     
Sbjct: 478 YLPENNIPGASIYKIQASDLDLGDNAKVIYSISNSNTEDFAVSSFFSINIETGVLYSQRS 537

Query: 855 LNTNVPKLATMEVSVTDG 872
            +    K+  ME+   DG
Sbjct: 538 FDYEQHKVFQMEIMARDG 555


>UniRef50_O15943 Cluster: Neural-cadherin precursor; n=42;
            Arthropoda|Rep: Neural-cadherin precursor - Drosophila
            melanogaster (Fruit fly)
          Length = 3097

 Score =  409 bits (1006), Expect = e-112
 Identities = 434/1687 (25%), Positives = 697/1687 (41%), Gaps = 178/1687 (10%)

Query: 15   DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTADTLNPE 73
            D ND  P+F  ++ E +V EG   GT V  + A D+D    N +V Y I     D+   E
Sbjct: 1291 DVNDEIPLFTEREQE-TVLEGEPIGTKVTQVNAIDKDGTFPNNQVYYYI----VDSPRNE 1345

Query: 74   DAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD---QASPVSDRL 130
                         ++ F I+ +SG + T+   DREK   Y + V+A D    A P S+  
Sbjct: 1346 G------------KEFFEINLQSGEIFTKTVFDREKKGAYALEVEARDGAPSARPNSNGP 1393

Query: 131  SS-TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            +S T  I + I D NDN P F +  Y   VDE+  +     +  + A D D   +S IRY
Sbjct: 1394 NSVTKFIRIGIADKNDNPPYFDKSLYEAEVDENEDIQHT--VLTVTAKDHD--ESSRIRY 1449

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             I  GN    F++ +++G + +   LDYE  R Y L + A D     + N T ++I+++D
Sbjct: 1450 EITSGNIGGAFAVKNMTGAIYVAGALDYETRRRYELRLAASDN---LKENYTTVIIHVKD 1506

Query: 250  VNDNAPRFYTSLFQESVSE----NVPIGYSIVRVQAYDADEGVNAELTYTMTDK--DYTG 303
            VNDN P F    ++  ++E    N+P    +++V A D D+     + Y +T +  D   
Sbjct: 1507 VNDNPPVFERPTYRTQITEEDDRNLP--KRVLQVTATDGDKDRPQNIVYFLTGQGIDPDN 1564

Query: 304  NVDLPITIDPRSGWVYTSGQLDRET---QAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
              +    I+  +G ++    LDR+    + +++  V A D G       A          
Sbjct: 1565 PANSKFDINRTTGEIFVLKPLDRDQPNGRPQWRFTVFAQDEGGEGLVGYADVQVNLKDIN 1624

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN-----RLHYEITGG---NTRGRF 412
                 F  G Y   + E+   G  V+T+TA D D+ N     RL Y I         G  
Sbjct: 1625 DNAPIFPQGVYFGNVTENGTAGMVVMTMTAVDYDDPNEGSNARLVYSIEKNVIEEETGSP 1684

Query: 413  SITSQNGRGLI-TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN 471
                +   G+I T    LD ++   Y + V A D GG   T    I + D N+  P F  
Sbjct: 1685 IFEIEPDTGVIKTAVCCLDRERTPDYSIQVVAMDGGGLKGTGTASIRVKDINDMPPQFTK 1744

Query: 472  APYTASVFE-DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ- 529
              +   V E D      + +++ T  D     +  Y +   I N          V N   
Sbjct: 1745 DEWFTEVDETDGTALPEMPILTVTVHDEDETNKFQYKV---IDNSGYGADKFTMVRNNDG 1801

Query: 530  TGAITTNKLLDRETM---SGYLLTVTARDGGVPSLSDTTDVEISVV-----DVNDNEPVF 581
            TG++   + LD E     +G+   +   D G  + +D   V  S V     D+NDN+P F
Sbjct: 1802 TGSLKIVQPLDYEDQLQSNGFRFRIQVNDKGEDNDNDKYHVAYSWVVVKLRDINDNKPHF 1861

Query: 582  KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641
            ++     ++ ED  VGT + +  ATD D G   ++ Y +D     +  F I+  +G +  
Sbjct: 1862 ERANVEVSVFEDTKVGTELEKFKATDPDQGGKSKVSYSIDRSSDRQRQFAINQ-NGSVTI 1920

Query: 642  NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701
             ++LDRE V  H +K +AID G+PP+++T  + + ++DIND+ P F  D     + E+ P
Sbjct: 1921 QRSLDREVVPRHQVKILAIDDGSPPKTATATLTVIVQDINDNAPKFLKDYRP-VLPEHVP 1979

Query: 702  IGTTIGEIRAHDPDEGPNAVVHYSIK---GGDD--SNSFSLETRQ----GSDKAELVTMV 752
                +  +   D D   +    +  +     DD    SF +E  Q    G   A + ++ 
Sbjct: 1980 PRKVVEILATDDDDRSKSNGPPFQFRLDPSADDIIRASFKVEQDQKGANGDGMAVISSLR 2039

Query: 753  DLDYESPRKKY--ELVIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809
              D E  +K+Y   +VI+   SP +     + +++ DVNDN        I   NY+   P
Sbjct: 2040 SFDREQ-QKEYMIPIVIKDHGSPAMTGTSTLTVIIGDVNDNKMQPGSKDIFVYNYQGQSP 2098

Query: 810  VGPFGRVPAYDADVTDKLQYRIL-SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVS 868
              P GRV  YD D  D    +            L+E +G +T+          L      
Sbjct: 2099 DTPIGRVYVYDLDDWDLPDKKFYWEAMEHPRFKLDEDSGMVTMRAGTREGRYHLRFKVYD 2158

Query: 869  VTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFL-----------SPLLGFFI 917
                  +I A + ++VR I  E ++NS +VRL+ ++ E F+              +  F 
Sbjct: 2159 RKHTQTDIPANVTVTVREIPHEAVVNSGSVRLSGISDEDFIRVWNYRTQSMSRSKMDRFR 2218

Query: 918  DGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRE 977
            D LA ++   +EN+ IFSVQ                  P  +V  +   SP+Y P  L  
Sbjct: 2219 DKLADLLNTERENVDIFSVQ------------LKRKHPPLTDVRFSAHGSPYYKPVRLNG 2266

Query: 978  RVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIY 1037
             V +HR  + +   + +     + C++E  +    C   L+       VN++      + 
Sbjct: 2267 IVLMHREEIEKDVGINITMVGIDECLYENQMCEGSCTNSLEISPLPYMVNANKTALVGVR 2326

Query: 1038 PVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAA 1097
              T   C C                SC      + C +G +CV  R G      CS    
Sbjct: 2327 VDTIADCTC-------GARNFTKPESCRT----TPCHNGGRCVDTRFG----PHCSCPVG 2371

Query: 1098 YTTAVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRY--NERHDFL 1155
            YT   C+   RSF  + +  +P L+     HL L+F T+   GL++YNG     ER + L
Sbjct: 2372 YTGPRCQQTTRSFRGNGWAWYPPLEMCDESHLSLEFITRKPDGLIIYNGPIVPPERDETL 2431

Query: 1156 ALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDC 1215
              + ++ E  R G P L   F  G  +  +  +  + DG WH +++ +   +I M++D C
Sbjct: 2432 ISDFIALELER-GYPRLLIDFGSGTLELRVKTKKTLDDGEWHRIDLFWDTESIRMVVDFC 2490

Query: 1216 DKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGL--PNIPSS 1273
             K   +A   D G       F      AR +IP    + +L++  PLQ+GGL       S
Sbjct: 2491 -KSAEIAEMED-GTP---PEFDDMSCQARGQIP--PFNEYLNVNAPLQVGGLYREQFDQS 2543

Query: 1274 -----FQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRC----SSAPCYN 1324
                 +    K F GCI +   + K  DL        ++AGCP+    C    ++A C+ 
Sbjct: 2544 LYFWHYMPTAKGFDGCIRNLVHNSKLYDLAHPGLSRNSVAGCPQTEEVCAQTETTARCWE 2603

Query: 1325 GAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLRPIQLPWLNALSIR 1384
               C        C C+ G TG  C   T  P  F     + +     P +      L  R
Sbjct: 2604 HGNCVGSLSEARCHCRPGWTGPACNIPT-IPTTFKAQSYVKYALSFEPDRFSTQVQLRFR 2662

Query: 1385 TRQR--DAFVMS---------IQLKSGLLHYSYN-------GETMYLPMATLSDGAWHRI 1426
            TR+   + F +S         +++K G LH+ YN        + ++L    ++DG WH +
Sbjct: 2663 TREEYGELFRVSDQHNREYGILEIKDGHLHFRYNLNSLRTEEKDLWLNAIVVNDGQWHVV 2722

Query: 1427 EIKWLGTDISVTVDYGL-RTVLMPMLANKIQGQYIGK---ILIGGLDTTAGLLASDV--G 1480
            ++   G+  ++ +D G  R           Q   + K   +  GG     G+   +V   
Sbjct: 2723 KVNRYGSAATLELDGGEGRRYNETFEFVGHQWLLVDKQEGVYAGGKAEYTGVRTFEVYAD 2782

Query: 1481 FFEGCIQDVRIGTAQSLL---------NRPTVRENVRDGCQSRADCMLSICPPYSKCVTS 1531
            + + C+ D+R+      L          + T+  N+  GC S   C   ICP   +CV  
Sbjct: 2783 YQKSCLDDIRLEGKHLPLPPAMNGTQWGQATMARNLEKGCPSNKPCSNVICPDPFECVDL 2842

Query: 1532 WDSSTCTCEAGRV-GPQ---CV--SACELGPC-GAARCVPDQTPKGYSCACEPGYTLTTS 1584
            W+   CTC  GR+  P    C+  + C   PC   A C+  +    Y C C  G+     
Sbjct: 2843 WNVYECTCGEGRIMSPDSKGCMDRNECLDMPCMNGATCINLEPRLRYRCICPDGFWGENC 2902

Query: 1585 GCIESGK 1591
              ++ G+
Sbjct: 2903 ELVQEGQ 2909



 Score =  339 bits (834), Expect = 5e-91
 Identities = 255/741 (34%), Positives = 377/741 (50%), Gaps = 64/741 (8%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR-LSSTATIHVNIIDDNDNYP 148
            F +D RSG + TR +   +    Y + VKA DQ   V DR   ST    ++I+      P
Sbjct: 591  FEVDERSGVVRTRGTDLFQLDMEYVLYVKAEDQNGKVDDRRFQSTPEERLSIVGGK-RAP 649

Query: 149  QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG-GNTQMQFSIDSLSG 207
            QF   +Y   + E+    D+ +I+ IKA      A+  IRY +   G     F+I   SG
Sbjct: 650  QFYMPSYEAEIPEN-QKKDSDIIS-IKAKSF---ADREIRYTLKAQGQGAGTFNIGPTSG 704

Query: 208  DVSLVKTLDYEQVRS---YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ- 263
             V L K LD+E +R    Y L++ A +  S   S +  L I + DVNDNAP+F    +Q 
Sbjct: 705  IVKLAKELDFEDLRQPHVYSLIVTATED-SGGFSTSVDLTIRVTDVNDNAPKFELPDYQA 763

Query: 264  ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323
             +V E++P+G SI+RV+A D+D G NAE+ Y ++D  +   VD        +G +  + Q
Sbjct: 764  HNVDEDIPLGTSILRVKAMDSDSGSNAEIEYLVSDDHFA--VD-------SNGIIVNNKQ 814

Query: 324  LDRETQ-AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382
            LD +   A Y+ +VTA D G+PP+S  AT              F    Y   + E+  P 
Sbjct: 815  LDADNNNAYYEFIVTAKDKGEPPKSGVATVRVYTKNKNDEEPKFSQQVYTPNVDENAGPN 874

Query: 383  TPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
            T V T+ A+D D DN     + GG + G+F I  ++  G+I +        + +Y L V+
Sbjct: 875  TLVTTVVASDKDGDNVRFGFVGGGTSSGQFVI--EDITGVIRLHNKAISLDKDKYELNVT 932

Query: 443  ATDSGG---------RSDTAMVQINITDANNYAPVFEN-APYTASVFEDAPIGTTVLVVS 492
            A D G           + TA+V + ITD N+  PVF++ + Y   V E AP G+ V+ V 
Sbjct: 933  AMDDGSCCVNGDQTIHTSTAVVVVFITDVNDNKPVFKDCSTYYPKVEEGAPNGSPVIKVV 992

Query: 493  ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552
            ATD D G+N Q+ YS+  + + +       +F ++ +TG ++TNK+ DRE   G  ++VT
Sbjct: 993  ATDEDKGVNGQVKYSIVQQPNQKGT-----KFTVDEETGEVSTNKVFDREGDDGKFVSVT 1047

Query: 553  --ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610
              A D G PSL       + + DVNDN P+F +Q Y  N+ +DA +GT++ +V A+D D 
Sbjct: 1048 VKATDQGDPSLEGVCSFTVEITDVNDNPPLFDRQKYVENVKQDASIGTNILRVSASDEDA 1107

Query: 611  GLNGRIHYEL----DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
              NG I Y L    +P D E   F I   SG I   K LDRE   T+ L+A+A D G PP
Sbjct: 1108 DNNGAIVYSLTAPFNPNDLE--YFEIQAESGWIVLKKPLDRE---TYKLEAMAQDKGYPP 1162

Query: 667  QSSTVIVHIKIEDINDSPPVFESDCL-TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
             S TV V I + D  ++PPV++       Y+ EN P+G  +  I+A    EG N  V Y 
Sbjct: 1163 LSRTVEVQIDVVDRANNPPVWDHTVYGPIYVKENMPVGGKVVSIKASSGIEG-NPTVFYR 1221

Query: 726  IKGGDDS-----NSFSLETR--QGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLW 775
            +  G  +     ++F L+ R   G   A++     LDYES  K+Y L IR     +  L 
Sbjct: 1222 LMPGSTAQTNKFHTFYLQQRPDNGDTWADIKVNHPLDYES-IKEYNLTIRVENNGAQQLA 1280

Query: 776  NDVRVEILVTDVNDNAPVMKD 796
            ++  V I++ DVND  P+  +
Sbjct: 1281 SEATVYIMLEDVNDEIPLFTE 1301



 Score =  309 bits (759), Expect = 6e-82
 Identities = 269/927 (29%), Positives = 428/927 (46%), Gaps = 91/927 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + + D ND+ P+F+ Q+Y  +V++ AS GT +L + A+D+D   N  + Y++   TA   
Sbjct: 1066 VEITDVNDNPPLFDRQKYVENVKQDASIGTNILRVSASDEDADNNGAIVYSL---TA-PF 1121

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            NP D             + F I   SG ++ +  LDRE    Y +   A D+  P    L
Sbjct: 1122 NPNDL------------EYFEIQAESGWIVLKKPLDRE---TYKLEAMAQDKGYP---PL 1163

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTY-TVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            S T  + ++++D  +N P +    Y  + V E++ V     +  IKA+ + +  N  + Y
Sbjct: 1164 SRTVEVQIDVVDRANNPPVWDHTVYGPIYVKENMPVGGK--VVSIKAS-SGIEGNPTVFY 1220

Query: 190  AIIGGNT-----------QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238
             ++ G+T           Q +        D+ +   LDYE ++ Y L IR ++ G+   +
Sbjct: 1221 RLMPGSTAQTNKFHTFYLQQRPDNGDTWADIKVNHPLDYESIKEYNLTIRVENNGAQQLA 1280

Query: 239  NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV-NAELTYTMT 297
            +   + I + DVND  P F T   QE+V E  PIG  + +V A D D    N ++ Y + 
Sbjct: 1281 SEATVYIMLEDVNDEIPLF-TEREQETVLEGEPIGTKVTQVNAIDKDGTFPNNQVYYYIV 1339

Query: 298  DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG-------GDPPRSATA 350
            D       +    I+ +SG ++T    DRE +  Y L V A DG        + P S T 
Sbjct: 1340 DSPRNEGKEF-FEINLQSGEIFTKTVFDREKKGAYALEVEARDGAPSARPNSNGPNSVTK 1398

Query: 351  TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG 410
                           F    YE E+ E+E     V+T+TA D DE +R+ YEIT GN  G
Sbjct: 1399 FIRIGIADKNDNPPYFDKSLYEAEVDENEDIQHTVLTVTAKDHDESSRIRYEITSGNIGG 1458

Query: 411  RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFE 470
             F++  +N  G I VA  LD++  RRY L ++A+D+   + T ++ I++ D N+  PVFE
Sbjct: 1459 AFAV--KNMTGAIYVAGALDYETRRRYELRLAASDNLKENYTTVI-IHVKDVNDNPPVFE 1515

Query: 471  NAPYTASVFE--DAPIGTTVLVVSATDSDVGINAQITYSLSSE-ISNEAVAHHDQQFVIN 527
               Y   + E  D  +   VL V+ATD D      I Y L+ + I  +  A  + +F IN
Sbjct: 1516 RPTYRTQITEEDDRNLPKRVLQVTATDGDKDRPQNIVYFLTGQGIDPDNPA--NSKFDIN 1573

Query: 528  PQTGAITTNKLLDRETMSG---YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584
              TG I   K LDR+  +G   +  TV A+D G   L    DV++++ D+NDN P+F Q 
Sbjct: 1574 RTTGEIFVLKPLDRDQPNGRPQWRFTVFAQDEGGEGLVGYADVQVNLKDINDNAPIFPQG 1633

Query: 585  LYTANIMEDALVGTSVSQVGATDAD---VGLNGRIHYELDPK--DREEGS--FVIDPASG 637
            +Y  N+ E+   G  V  + A D D    G N R+ Y ++    + E GS  F I+P +G
Sbjct: 1634 VYFGNVTENGTAGMVVMTMTAVDYDDPNEGSNARLVYSIEKNVIEEETGSPIFEIEPDTG 1693

Query: 638  VIRTNK-ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696
            VI+T    LDRE    + ++ VA+DGG    + T    I+++DIND PP F  D   ++ 
Sbjct: 1694 VIKTAVCCLDRERTPDYSIQVVAMDGGGLKGTGT--ASIRVKDINDMPPQFTKD--EWFT 1749

Query: 697  SENSPIGTTIGE-----IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751
              +   GT + E     +  HD DE            G  ++ F++  R       L  +
Sbjct: 1750 EVDETDGTALPEMPILTVTVHDEDETNKFQYKVIDNSGYGADKFTM-VRNNDGTGSLKIV 1808

Query: 752  VDLDYESPRK----KYELVIRAASPPLWNDVR------VEILVTDVNDNAPVMKDFQIIF 801
              LDYE   +    ++ + +        ND        V + + D+NDN P  +   +  
Sbjct: 1809 QPLDYEDQLQSNGFRFRIQVNDKGEDNDNDKYHVAYSWVVVKLRDINDNKPHFERANVEV 1868

Query: 802  NNYKDCFPVGPFGRVPAYDADV--TDKLQYRI-LSGNNANLILLNETTGSMTLSPQLNTN 858
            + ++D        +  A D D     K+ Y I  S +      +N+  GS+T+   L+  
Sbjct: 1869 SVFEDTKVGTELEKFKATDPDQGGKSKVSYSIDRSSDRQRQFAINQ-NGSVTIQRSLDRE 1927

Query: 859  -VPKLATMEVSVTDGVNEIKAMMQLSV 884
             VP+     +++ DG     A   L+V
Sbjct: 1928 VVPRHQVKILAIDDGSPPKTATATLTV 1954



 Score =  291 bits (713), Expect = 2e-76
 Identities = 251/820 (30%), Positives = 380/820 (46%), Gaps = 83/820 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEA-SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            I V D ND++P FE+  Y+A +V E    GT++L +KA D D G NAE+EY +       
Sbjct: 744  IRVTDVNDNAPKFELPDYQAHNVDEDIPLGTSILRVKAMDSDSGSNAEIEYLVS------ 797

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDRE-KVARYTVLVKATDQASPVSD 128
                              D F +D  +G ++    LD +   A Y  +V A D+  P   
Sbjct: 798  -----------------DDHFAVDS-NGIIVNNKQLDADNNNAYYEFIVTAKDKGEPPK- 838

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
              S  AT+ V   + ND  P+FS++ YT +VDE+     N ++  + A+D D G N  +R
Sbjct: 839  --SGVATVRVYTKNKNDEEPKFSQQVYTPNVDENAG--PNTLVTTVVASDKD-GDN--VR 891

Query: 189  YAIIGGNTQM-QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS-------PSRSNT 240
            +  +GG T   QF I+ ++G + L           Y L + A D GS          ++T
Sbjct: 892  FGFVGGGTSSGQFVIEDITGVIRLHNKAISLDKDKYELNVTAMDDGSCCVNGDQTIHTST 951

Query: 241  TQLLINIRDVNDNAPRFY-TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
              +++ I DVNDN P F   S +   V E  P G  +++V A D D+GVN ++ Y++  +
Sbjct: 952  AVVVVFITDVNDNKPVFKDCSTYYPKVEEGAPNGSPVIKVVATDEDKGVNGQVKYSIVQQ 1011

Query: 300  DYTGNVDLPITIDPRSGWVYTSGQLDRE-TQAKY-QLLVTATDGGDPPRSATATXXXXXX 357
                      T+D  +G V T+   DRE    K+  + V ATD GDP      +      
Sbjct: 1012 --PNQKGTKFTVDEETGEVSTNKVFDREGDDGKFVSVTVKATDQGDPSLEGVCSFTVEIT 1069

Query: 358  XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEIT---GGNTRGRF 412
                    F   +Y   + +D   GT ++ ++A+D D DN   + Y +T     N    F
Sbjct: 1070 DVNDNPPLFDRQKYVENVKQDASIGTNILRVSASDEDADNNGAIVYSLTAPFNPNDLEYF 1129

Query: 413  SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFE 470
             I +++  G I + +PLD      Y L   A D G    S T  VQI++ D  N  PV++
Sbjct: 1130 EIQAES--GWIVLKKPLD---RETYKLEAMAQDKGYPPLSRTVEVQIDVVDRANNPPVWD 1184

Query: 471  NAPY-TASVFEDAPIGTTVLVVSATDSDVGINAQITYSL---SSEISNEAVAHHDQQFVI 526
            +  Y    V E+ P+G  V+ + A+    G N  + Y L   S+  +N+    + QQ   
Sbjct: 1185 HTVYGPIYVKENMPVGGKVVSIKASSGIEG-NPTVFYRLMPGSTAQTNKFHTFYLQQRPD 1243

Query: 527  NPQTGA-ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585
            N  T A I  N  LD E++  Y LT+   + G   L+    V I + DVND  P+F ++ 
Sbjct: 1244 NGDTWADIKVNHPLDYESIKEYNLTIRVENNGAQQLASEATVYIMLEDVNDEIPLFTER- 1302

Query: 586  YTANIMEDALVGTSVSQVGATDADVGL-NGRIHYELDPKDREEGS--FVIDPASGVIRTN 642
                ++E   +GT V+QV A D D    N +++Y +    R EG   F I+  SG I T 
Sbjct: 1303 EQETVLEGEPIGTKVTQVNAIDKDGTFPNNQVYYYIVDSPRNEGKEFFEINLQSGEIFTK 1362

Query: 643  KALDRESVATHDLKAVAIDG-------GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695
               DRE    + L+  A DG          P S T  + I I D ND+PP F+       
Sbjct: 1363 TVFDREKKGAYALEVEARDGAPSARPNSNGPNSVTKFIRIGIADKNDNPPYFDKSLYEAE 1422

Query: 696  ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755
            + EN  I  T+  + A D DE  ++ + Y I  G+   +F+++   G+    +     LD
Sbjct: 1423 VDENEDIQHTVLTVTAKDHDE--SSRIRYEITSGNIGGAFAVKNMTGA----IYVAGALD 1476

Query: 756  YESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMK 795
            YE+ R++YEL + A+     N   V I V DVNDN PV +
Sbjct: 1477 YET-RRRYELRLAASDNLKENYTTVIIHVKDVNDNPPVFE 1515



 Score =  236 bits (578), Expect = 6e-60
 Identities = 203/750 (27%), Positives = 333/750 (44%), Gaps = 81/750 (10%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I + D ND+ P F+   YEA V E      TVLT+ A D D  +++ + Y I       
Sbjct: 1401 RIGIADKNDNPPYFDKSLYEAEVDENEDIQHTVLTVTAKDHD--ESSRIRYEI------- 1451

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                            +   F +   +GA+    +LD E   RY + + A+D        
Sbjct: 1452 ------------TSGNIGGAFAVKNMTGAIYVAGALDYETRRRYELRLAASDNLK----- 1494

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
              +  T+ +++ D NDN P F   TY   + E+        + ++ ATD D      I Y
Sbjct: 1495 -ENYTTVIIHVKDVNDNPPVFERPTYRTQITEEDDRNLPKRVLQVTATDGDKDRPQNIVY 1553

Query: 190  AIIG------GNTQMQFSIDSLSGDVSLVKTLDYEQVR---SYRLVIRAQDGGSPSRSNT 240
             + G           +F I+  +G++ ++K LD +Q      +R  + AQD G       
Sbjct: 1554 FLTGQGIDPDNPANSKFDINRTTGEIFVLKPLDRDQPNGRPQWRFTVFAQDEGGEGLVGY 1613

Query: 241  TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD---EGVNAELTYTMT 297
              + +N++D+NDNAP F   ++  +V+EN   G  ++ + A D D   EG NA L Y++ 
Sbjct: 1614 ADVQVNLKDINDNAPIFPQGVYFGNVTENGTAGMVVMTMTAVDYDDPNEGSNARLVYSIE 1673

Query: 298  DKDYTGNVDLPI-TIDPRSGWVYTS-GQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355
                      PI  I+P +G + T+   LDRE    Y + V A DGG      T T    
Sbjct: 1674 KNVIEEETGSPIFEIEPDTGVIKTAVCCLDRERTPDYSIQVVAMDGGG--LKGTGTASIR 1731

Query: 356  XXXXXXXXXXFMPGQYEVELAEDEP---PGTPVVTLTATDADEDNRLHYEITGGNTRG-- 410
                      F   ++  E+ E +    P  P++T+T  D DE N+  Y++   +  G  
Sbjct: 1732 VKDINDMPPQFTKDEWFTEVDETDGTALPEMPILTVTVHDEDETNKFQYKVIDNSGYGAD 1791

Query: 411  RFSITSQN-GRGLITVAQPLDFK---QERRYVLTVSATDSGGRSDT-------AMVQINI 459
            +F++   N G G + + QPLD++   Q   +   +   D G  +D        + V + +
Sbjct: 1792 KFTMVRNNDGTGSLKIVQPLDYEDQLQSNGFRFRIQVNDKGEDNDNDKYHVAYSWVVVKL 1851

Query: 460  TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAH 519
             D N+  P FE A    SVFED  +GT +    ATD D G  ++++YS+      +  + 
Sbjct: 1852 RDINDNKPHFERANVEVSVFEDTKVGTELEKFKATDPDQGGKSKVSYSI------DRSSD 1905

Query: 520  HDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP 579
              +QF IN Q G++T  + LDRE +  + + + A D G P  + T  + + V D+NDN P
Sbjct: 1906 RQRQFAIN-QNGSVTIQRSLDREVVPRHQVKILAIDDGSPPKTATATLTVIVQDINDNAP 1964

Query: 580  VFKQQLYTANIMEDALVGTSVSQVGATDAD--VGLNG-RIHYELDPK--DREEGSFVIDP 634
             F +      ++ + +    V ++ ATD D     NG    + LDP   D    SF ++ 
Sbjct: 1965 KFLKDY--RPVLPEHVPPRKVVEILATDDDDRSKSNGPPFQFRLDPSADDIIRASFKVEQ 2022

Query: 635  ----ASG----VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686
                A+G    VI + ++ DRE    + +  V  D G+P  + T  + + I D+ND+   
Sbjct: 2023 DQKGANGDGMAVISSLRSFDREQQKEYMIPIVIKDHGSPAMTGTSTLTVIIGDVNDNKMQ 2082

Query: 687  FESDCLTFYISENSPIGTTIGEIRAHDPDE 716
              S  +  Y  +     T IG +  +D D+
Sbjct: 2083 PGSKDIFVYNYQGQSPDTPIGRVYVYDLDD 2112



 Score =  219 bits (536), Expect = 7e-55
 Identities = 209/697 (29%), Positives = 316/697 (45%), Gaps = 65/697 (9%)

Query: 206  SGDVSLVKTLDYEQVRSYR------LVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259
            +G V + K  DYE++   +      ++           ++  +++I ++DVND  P F  
Sbjct: 486  NGAVRVKKKWDYEELGPEKTIDFWVIITNMGHNAGIKYTDNQRVIILVKDVNDEPPYFIN 545

Query: 260  S--LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317
                 Q  V  N P    +  +QA D D   N  + Y +  +D TG       +D RSG 
Sbjct: 546  RPLPMQAVVQLNAPPNTPVFTLQARDPDTDHN--IHYFIV-RDRTGG---RFEVDERSGV 599

Query: 318  VYTSGQLDRETQAKYQLLVTATDGG---DPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374
            V T G    +   +Y L V A D     D  R  +                F    YE E
Sbjct: 600  VRTRGTDLFQLDMEYVLYVKAEDQNGKVDDRRFQSTPEERLSIVGGKRAPQFYMPSYEAE 659

Query: 375  LAEDEPPGTPVVTLTATDADEDNRLHYEITG-GNTRGRFSITSQNGRGLITVAQPLDFKQ 433
            + E++   + ++++ A  +  D  + Y +   G   G F+I   +  G++ +A+ LDF+ 
Sbjct: 660  IPENQKKDSDIISIKA-KSFADREIRYTLKAQGQGAGTFNIGPTS--GIVKLAKELDFED 716

Query: 434  ERR---YVLTVSAT-DSGGRSDTAMVQINITDANNYAPVFENAPYTA-SVFEDAPIGTTV 488
             R+   Y L V+AT DSGG S +  + I +TD N+ AP FE   Y A +V ED P+GT++
Sbjct: 717  LRQPHVYSLIVTATEDSGGFSTSVDLTIRVTDVNDNAPKFELPDYQAHNVDEDIPLGTSI 776

Query: 489  LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
            L V A DSD G NA+I Y +S           D  F ++   G I  NK LD +  + Y 
Sbjct: 777  LRVKAMDSDSGSNAEIEYLVS-----------DDHFAVD-SNGIIVNNKQLDADNNNAYY 824

Query: 549  -LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
               VTA+D G P  S    V +   + ND EP F QQ+YT N+ E+A   T V+ V A+D
Sbjct: 825  EFIVTAKDKGEPPKSGVATVRVYTKNKNDEEPKFSQQVYTPNVDENAGPNTLVTTVVASD 884

Query: 608  ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT-NKA--LDRE----SVATHDLKAVAI 660
             D      + +         G FVI+  +GVIR  NKA  LD++    +V   D  +  +
Sbjct: 885  KD---GDNVRFGFVGGGTSSGQFVIEDITGVIRLHNKAISLDKDKYELNVTAMDDGSCCV 941

Query: 661  DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY--ISENSPIGTTIGEIRAHDPDEGP 718
            +G     +ST +V + I D+ND+ PVF+ DC T+Y  + E +P G+ + ++ A D D+G 
Sbjct: 942  NGDQTIHTSTAVVVVFITDVNDNKPVFK-DCSTYYPKVEEGAPNGSPVIKVVATDEDKGV 1000

Query: 719  NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY-ELVIRA---ASPPL 774
            N  V YSI      N    +     +  E+ T    D E    K+  + ++A     P L
Sbjct: 1001 NGQVKYSIV--QQPNQKGTKFTVDEETGEVSTNKVFDREGDDGKFVSVTVKATDQGDPSL 1058

Query: 775  WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPA--YDADVTDKLQYRI 831
                   + +TDVNDN P+  D Q    N K    +G    RV A   DAD    + Y +
Sbjct: 1059 EGVCSFTVEITDVNDNPPLF-DRQKYVENVKQDASIGTNILRVSASDEDADNNGAIVYSL 1117

Query: 832  LSGNNAN---LILLNETTGSMTLSPQLNTNVPKLATM 865
             +  N N      +   +G + L   L+    KL  M
Sbjct: 1118 TAPFNPNDLEYFEIQAESGWIVLKKPLDRETYKLEAM 1154



 Score =  193 bits (470), Expect = 7e-47
 Identities = 201/759 (26%), Positives = 321/759 (42%), Gaps = 56/759 (7%)

Query: 105  LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS 164
            L  EK   + V++  T+       + +    + + + D ND  P F  +   +     ++
Sbjct: 500  LGPEKTIDFWVII--TNMGHNAGIKYTDNQRVIILVKDVNDEPPYFINRPLPMQAVVQLN 557

Query: 165  VTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR 224
               N  +  ++A D D   N  I Y I+   T  +F +D  SG V    T  ++    Y 
Sbjct: 558  APPNTPVFTLQARDPDTDHN--IHYFIVRDRTGGRFEVDERSGVVRTRGTDLFQLDMEYV 615

Query: 225  LVIRAQD--GGSPSR--SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQ 280
            L ++A+D  G    R   +T +  ++I      AP+FY   ++  + EN      I+ ++
Sbjct: 616  LYVKAEDQNGKVDDRRFQSTPEERLSIVG-GKRAPQFYMPSYEAEIPENQKKDSDIISIK 674

Query: 281  AYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK---YQLLVT 337
               A    + E+ YT+  +   G       I P SG V  + +LD E   +   Y L+VT
Sbjct: 675  ---AKSFADREIRYTLKAQ---GQGAGTFNIGPTSGIVKLAKELDFEDLRQPHVYSLIVT 728

Query: 338  ATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN 397
            AT+      ++                  +P      + ED P GT ++ + A D+D  +
Sbjct: 729  ATEDSGGFSTSVDLTIRVTDVNDNAPKFELPDYQAHNVDEDIPLGTSILRVKAMDSDSGS 788

Query: 398  RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYV-LTVSATDSG--GRSDTAM 454
                E    +    F++ S    G+I   + LD      Y    V+A D G   +S  A 
Sbjct: 789  NAEIEYLVSD--DHFAVDS---NGIIVNNKQLDADNNNAYYEFIVTAKDKGEPPKSGVAT 843

Query: 455  VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
            V++   + N+  P F    YT +V E+A   T V  V A+D D G N +  +      S 
Sbjct: 844  VRVYTKNKNDEEPKFSQQVYTPNVDENAGPNTLVTTVVASDKD-GDNVRFGFVGGGTSSG 902

Query: 515  EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL-------SDTTDV 567
                    QFVI   TG I  +          Y L VTA D G   +       + T  V
Sbjct: 903  --------QFVIEDITGVIRLHNKAISLDKDKYELNVTAMDDGSCCVNGDQTIHTSTAVV 954

Query: 568  EISVVDVNDNEPVFKQ-QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE 626
             + + DVNDN+PVFK    Y   + E A  G+ V +V ATD D G+NG++ Y +  +  +
Sbjct: 955  VVFITDVNDNKPVFKDCSTYYPKVEEGAPNGSPVIKVVATDEDKGVNGQVKYSIVQQPNQ 1014

Query: 627  EGS-FVIDPASGVIRTNKALDRESVATH--DLKAVAIDGGTPPQSSTVIVHIKIEDINDS 683
            +G+ F +D  +G + TNK  DRE        +   A D G P         ++I D+ND+
Sbjct: 1015 KGTKFTVDEETGEVSTNKVFDREGDDGKFVSVTVKATDQGDPSLEGVCSFTVEITDVNDN 1074

Query: 684  PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
            PP+F+       + +++ IGT I  + A D D   N  + YS+    + N       Q +
Sbjct: 1075 PPLFDRQKYVENVKQDASIGTNILRVSASDEDADNNGAIVYSLTAPFNPNDLEYFEIQ-A 1133

Query: 744  DKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN 803
            +   +V    LD E+  K   +      PPL   V V+I V D  +N PV  D  +    
Sbjct: 1134 ESGWIVLKKPLDRET-YKLEAMAQDKGYPPLSRTVEVQIDVVDRANNPPVW-DHTVYGPI 1191

Query: 804  Y-KDCFPVGPFGRVPAYDA----DVTDKLQYRILSGNNA 837
            Y K+  PVG  G+V +  A    +    + YR++ G+ A
Sbjct: 1192 YVKENMPVG--GKVVSIKASSGIEGNPTVFYRLMPGSTA 1228



 Score =  161 bits (391), Expect = 3e-37
 Identities = 155/533 (29%), Positives = 239/533 (44%), Gaps = 56/533 (10%)

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
            +P Q  V+L  + PP TPV TL A D D D+ +HY I    T GRF +  ++  G++   
Sbjct: 548  LPMQAVVQL--NAPPNTPVFTLQARDPDTDHNIHYFIVRDRTGGRFEVDERS--GVVRTR 603

Query: 427  QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITD-----ANNYAPVFENAPYTASVFED 481
                F+ +  YVL V A D  G+ D    Q    +         AP F    Y A + E+
Sbjct: 604  GTDLFQLDMEYVLYVKAEDQNGKVDDRRFQSTPEERLSIVGGKRAPQFYMPSYEAEIPEN 663

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
                + ++ + A       + +I Y+L ++            F I P +G +   K LD 
Sbjct: 664  QKKDSDIISIKAKSF---ADREIRYTLKAQGQGAGT------FNIGPTSGIVKLAKELDF 714

Query: 542  ETMSG---YLLTVTA-RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA-NIMEDALV 596
            E +     Y L VTA  D G    S + D+ I V DVNDN P F+   Y A N+ ED  +
Sbjct: 715  EDLRQPHVYSLIVTATEDSG--GFSTSVDLTIRVTDVNDNAPKFELPDYQAHNVDEDIPL 772

Query: 597  GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE-SVATHDL 655
            GTS+ +V A D+D G N  I Y +      +  F +D ++G+I  NK LD + + A ++ 
Sbjct: 773  GTSILRVKAMDSDSGSNAEIEYLV-----SDDHFAVD-SNGIIVNNKQLDADNNNAYYEF 826

Query: 656  KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
               A D G PP+S    V +  ++ ND  P F     T  + EN+   T +  + A D D
Sbjct: 827  IVTAKDKGEPPKSGVATVRVYTKNKNDEEPKFSQQVYTPNVDENAGPNTLVTTVVASDKD 886

Query: 716  EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASP 772
             G N    + + GG  S  F +E     D   ++ + +      + KYEL + A    S 
Sbjct: 887  -GDNVRFGF-VGGGTSSGQFVIE-----DITGVIRLHNKAISLDKDKYELNVTAMDDGSC 939

Query: 773  PLWNDVRVE-------ILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD-- 822
             +  D  +        + +TDVNDN PV KD    +   ++  P G P  +V A D D  
Sbjct: 940  CVNGDQTIHTSTAVVVVFITDVNDNKPVFKDCSTYYPKVEEGAPNGSPVIKVVATDEDKG 999

Query: 823  VTDKLQYRILSGNN--ANLILLNETTGSMTLSPQLNT--NVPKLATMEVSVTD 871
            V  +++Y I+   N       ++E TG ++ +   +   +  K  ++ V  TD
Sbjct: 1000 VNGQVKYSIVQQPNQKGTKFTVDEETGEVSTNKVFDREGDDGKFVSVTVKATD 1052



 Score = 68.1 bits (159), Expect = 3e-09
 Identities = 91/370 (24%), Positives = 158/370 (42%), Gaps = 38/370 (10%)

Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT-AMVQINITDANNYAPVFENAPYT 475
           ++G  L+T  +PLD ++   Y L+V A+D  G   T + +QI + D N+  P+F++  Y 
Sbjct: 253 ESGVWLVT-NRPLDREERAHYDLSVEASDVDGLDRTVSKIQITVLDENDNRPIFKSLDYK 311

Query: 476 ASVF--EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
            ++   + A + +   V     + +G   + T +   +I+   +       +I PQTG I
Sbjct: 312 FAIAGQKSASMESNSSVTYQRFAIMG-KVEATDADGDKIAYR-LKSPSNVVIIVPQTGEI 369

Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV--FKQQLYTANI- 590
               L    T +  L+ V A D   PSL      ++ +++    EPV    Q L   +I 
Sbjct: 370 ---MLAGEPTSNELLIEVIAHDLRYPSLVSAKPAKV-LLEFLAAEPVSFIMQHLEHDDIN 425

Query: 591 -----MEDALVGTSV---SQVGATDADVGLNGRIHYELDP-------KDREEGSFVIDPA 635
                 E   V  +V    ++  T+AD    G+  ++L+        K R++  +V    
Sbjct: 426 NHSHHREKRRVTRAVRPTKRIEFTEADGDTEGKSVFQLEKETDKETFKIRDDNPWVTVET 485

Query: 636 SGVIRTNKALDRESVA---THDLKAVAIDGGTP---PQSSTVIVHIKIEDINDSPPVFES 689
           +G +R  K  D E +    T D   +  + G       +    V I ++D+ND PP F +
Sbjct: 486 NGAVRVKKKWDYEELGPEKTIDFWVIITNMGHNAGIKYTDNQRVIILVKDVNDEPPYFIN 545

Query: 690 DCLTF--YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747
             L     +  N+P  T +  ++A DPD   N  +HY I        F ++ R G  +  
Sbjct: 546 RPLPMQAVVQLNAPPNTPVFTLQARDPDTDHN--IHYFIVRDRTGGRFEVDERSGVVRTR 603

Query: 748 LVTMVDLDYE 757
              +  LD E
Sbjct: 604 GTDLFQLDME 613



 Score = 46.0 bits (104), Expect = 0.015
 Identities = 42/145 (28%), Positives = 67/145 (46%), Gaps = 18/145 (12%)

Query: 49  DQDIGKNAEVEYTI-ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGA-LLTRASLD 106
           D+++    +V YTI +    D    ++              V   D  SG  L+T   LD
Sbjct: 206 DEELATPKKVRYTIIDGNVDDAFALQERKANKNIQISAKSLVINGDDESGVWLVTNRPLD 265

Query: 107 REKVARYTVLVKATDQASPVSDRLSSTAT-IHVNIIDDNDNYPQFSEKTY--------TV 157
           RE+ A Y + V+A+D      D L  T + I + ++D+NDN P F    Y        + 
Sbjct: 266 REERAHYDLSVEASDV-----DGLDRTVSKIQITVLDENDNRPIFKSLDYKFAIAGQKSA 320

Query: 158 SVDEDISVTDN--PVIAKIKATDAD 180
           S++ + SVT     ++ K++ATDAD
Sbjct: 321 SMESNSSVTYQRFAIMGKVEATDAD 345



 Score = 45.6 bits (103), Expect = 0.020
 Identities = 31/90 (34%), Positives = 48/90 (53%), Gaps = 6/90 (6%)

Query: 501 NAQITYSLSSEISNEAVAHHDQQFVIN--PQTGA-ITTNKLLDRETMSGYLLTVTARDGG 557
           N    ++L    +N+ +    +  VIN   ++G  + TN+ LDRE  + Y L+V A D  
Sbjct: 223 NVDDAFALQERKANKNIQISAKSLVINGDDESGVWLVTNRPLDREERAHYDLSVEASD-- 280

Query: 558 VPSLSDTTD-VEISVVDVNDNEPVFKQQLY 586
           V  L  T   ++I+V+D NDN P+FK   Y
Sbjct: 281 VDGLDRTVSKIQITVLDENDNRPIFKSLDY 310


>UniRef50_UPI00006A0F32 Cluster: dachsous 2 isoform 1; n=1; Xenopus
            tropicalis|Rep: dachsous 2 isoform 1 - Xenopus tropicalis
          Length = 2474

 Score =  407 bits (1001), Expect = e-111
 Identities = 303/918 (33%), Positives = 455/918 (49%), Gaps = 73/918 (7%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++++ D ND+ PVF    Y A + E    G+++  ++A D D G NA+V Y+I       
Sbjct: 1199 KLDLSDVNDNPPVFSKPTYVAYLPENNLPGSSIYRIQAFDFDSGNNAKVVYSI------- 1251

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            LN              V   F I+  SG L  + S D E+   +++ + A D  SP    
Sbjct: 1252 LN-------TYIQDIPVSAYFSINVVSGVLYAQRSFDYEQHQMFSMEITARDSGSPP--- 1301

Query: 130  LSSTATIHVNIIDDNDNYPQF---SEKTYTVSVDEDISVTDNP--VIAKIKATDADVGAN 184
            L+S  T+ + IID NDN P+    S      S+ E + +      +I K+ A DAD G N
Sbjct: 1302 LNSNITLIIYIIDQNDNAPEILYPSPNGGGSSLFEMVPLASEQGSLITKVIAVDADSGHN 1361

Query: 185  SAIRYAIIGGNTQMQFSIDSLSGDV-SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
            S + Y  I  +    FSI+  +G++ +  K LD E ++ ++L++ A DGG+P R+ T  +
Sbjct: 1362 SWLSYHFIPMSDPSPFSINQYTGEIRTCQKPLDRENLKIHKLLLTAFDGGNPVRTGTALI 1421

Query: 244  LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
             I I DVND+ P F   +++ S+SE++PI  ++++V A D DEGVNA++TY++       
Sbjct: 1422 RIAITDVNDHIPMFTQEVYKVSISESIPINTTVLQVNATDKDEGVNAQITYSLIRTSGDS 1481

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVT----ATDGGDPPRSATATXXXXXXXX 359
                  +I+P SG + T   L+ E Q  Y++ V     ATDGG+P R+ TA         
Sbjct: 1482 LASATFSINPASGEIKTKRNLNFEVQKHYEMSVEAKDGATDGGNPKRTGTALLRIIVTDY 1541

Query: 360  XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGR------FS 413
                  F    Y++ ++E  P  + V  +TATD D+    H   +   T         F+
Sbjct: 1542 NDNVPVFTQQVYKISISESAPINSTVTVVTATDKDDGTNGHITYSFSRTAENAFHTQMFN 1601

Query: 414  ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFE 470
            I   NG     V+   +   E   V    +T  GG   R+ TA+++I +TD+N+  PVF 
Sbjct: 1602 INPANGEIKTKVS---NINTEDFPVSPYFSTSDGGNPLRTGTALIRIIVTDSNDNLPVFT 1658

Query: 471  NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
               Y  SV E+API +TV++++ATD D G NA+ITYS+S    N     +   F INP T
Sbjct: 1659 QEVYKVSVSENAPINSTVIILTATDKDEGTNAKITYSISKTSKNN---FYTSIFHINPAT 1715

Query: 531  GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590
            G ITT + L+ E    Y ++V A DGG   L   + V I + DVNDN PVF Q +Y A+I
Sbjct: 1716 GEITTKENLNFENKEHYEMSVQAEDGG--GLVAQSKVLIEITDVNDNVPVFTQAVYKASI 1773

Query: 591  MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG---VIRTNKALDR 647
             E++ V T+V  V ATD D G+N +I Y        E SF +D ++G    I T  ALDR
Sbjct: 1774 SENSPVNTTVLYVNATDKDEGINAQIVYSF--SKTSENSFHLDSSTGRFYRIVTKSALDR 1831

Query: 648  ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
            E  A +++  VA D G+P  SS   + + I D+ND+PPVF       Y+ EN+  G++I 
Sbjct: 1832 EKTALYNITIVATDKGSPQLSSRKFIRLDISDVNDNPPVFMKSKDVAYLPENNLPGSSIY 1891

Query: 708  EIRAHDPDEGPNAVVHYSIKGGDD-----SNSFSLETRQGSDKAELVTMVDLDYESPRKK 762
             I+A D D G NA V YSI   D+     S+ FS+    G     L      DYE   K+
Sbjct: 1892 RIQASDLDTGDNAKVIYSISSMDNEDFPISSYFSINIETG----VLYAQRSFDYEQV-KE 1946

Query: 763  YELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPA 818
            +++ I A+   +P       + I VTD NDN PV    ++   +  +  P+      V A
Sbjct: 1947 FQIQITASDGGNPVRSGTALIRIAVTDANDNLPVFTQ-EVYKVSISENIPINSTVLTVNA 2005

Query: 819  YDADVTDKLQYRILSGNNANLILLNETTGS-------MTLSPQLNTNVPKLATMEVSVTD 871
             D D     Q   LS N      LNE T S       + L   L+     +  + ++ +D
Sbjct: 2006 TDRDEGTNAQSYRLSDN--QYFRLNEKTNSDLSKTPELVLEKPLDRETQSIHELILTASD 2063

Query: 872  GVNEIKAMMQLSVRLITE 889
            G N ++    L   ++T+
Sbjct: 2064 GGNPLRTGTALIRIIVTD 2081



 Score =  380 bits (936), Expect = e-103
 Identities = 250/750 (33%), Positives = 399/750 (53%), Gaps = 55/750 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I + D ND+ PVF    Y+AS+ E +   TTVL + ATD+D G NA++ Y+    + ++ 
Sbjct: 1752 IEITDVNDNVPVFTQAVYKASISENSPVNTTVLYVNATDKDEGINAQIVYSFSKTSENSF 1811

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            + + +                  GR   ++T+++LDREK A Y + + ATD+ SP   +L
Sbjct: 1812 HLDSST-----------------GRFYRIVTKSALDREKTALYNITIVATDKGSP---QL 1851

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            SS   I ++I D NDN P F +      + E+     +  I +I+A+D D G N+ + Y+
Sbjct: 1852 SSRKFIRLDISDVNDNPPVFMKSKDVAYLPENNLPGSS--IYRIQASDLDTGDNAKVIYS 1909

Query: 191  IIGGNTQ-----MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
            I   + +       FSI+  +G +   ++ DYEQV+ +++ I A DGG+P RS T  + I
Sbjct: 1910 ISSMDNEDFPISSYFSINIETGVLYAQRSFDYEQVKEFQIQITASDGGNPVRSGTALIRI 1969

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
             + D NDN P F   +++ S+SEN+PI  +++ V A D DEG NA+ +Y ++D  Y    
Sbjct: 1970 AVTDANDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQ-SYRLSDNQYFRLN 2028

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
            +   +   ++  +     LDRETQ+ ++L++TA+DGG+P R+ TA               
Sbjct: 2029 EKTNSDLSKTPELVLEKPLDRETQSIHELILTASDGGNPLRTGTALIRIIVTDSNDNLPV 2088

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRF-SITSQNG--- 419
            F    Y+V ++E+ P  + V+ LTATD DE    ++ Y I+  +    + S+ + N    
Sbjct: 2089 FTQEVYKVSISENAPINSSVIILTATDKDEGTNAQITYSISKTSENNFYTSVFNINPVIY 2148

Query: 420  ----RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAP 473
                   + + +PLD + ++ + L ++A+D G   ++ TA+++I +TDAN+  PVF  A 
Sbjct: 2149 YKIVNTELMLEKPLDRETQKDHELILTASDGGDPVKTGTAIIRIIVTDANDNLPVFTKAV 2208

Query: 474  YTASVFEDAPIGTTVLVVSATDSDVGINAQITYS-LSSEISNEAVAHHDQQFVINPQTGA 532
            Y  S+ E+ PI ++VL V+ATD D G NAQITYS + + +S+         F IN +TG 
Sbjct: 2209 YKVSISENIPINSSVLHVNATDRDEGTNAQITYSFIKTSVSS--------YFSINIETGV 2260

Query: 533  ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP-VFKQQLYTANIM 591
            +   +  D E    + + V A+D G PSLS    + I ++D NDN P +        +I 
Sbjct: 2261 LYAQRSFDYEQHKEFAMHVQAKDNGYPSLSSNATLIIRIIDQNDNAPKILYPSTENMSIS 2320

Query: 592  EDALVGTSVSQVGATDADVGLNGRIHYELDP---KDREEGSFVIDPASGVIRTNKALDRE 648
            E+  + ++V +V A+D D G N +I Y              F I+P SG I+TN  L+ E
Sbjct: 2321 ENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEIKTNNLLNYE 2380

Query: 649  SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
            ++  +++   A DGG     S ++V  +I D+ND+PPVF     T Y+ EN+  G TI  
Sbjct: 2381 AIRDYEISVQAKDGGGFVAHSKILV--EITDVNDNPPVFIKSAYTIYLPENNLPGATIYR 2438

Query: 709  IRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738
            I A D D G NA V YSI   +   S  LE
Sbjct: 2439 IHALDLDMGDNAKVIYSIYVSEKYFSVDLE 2468



 Score =  375 bits (923), Expect = e-102
 Identities = 267/836 (31%), Positives = 409/836 (48%), Gaps = 51/836 (6%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I V D ND+ PVF  + Y+ SV E A   +TV+ L ATD+D G NA++ Y+I   + + 
Sbjct: 1644 RIIVTDSNDNLPVFTQEVYKVSVSENAPINSTVIILTATDKDEGTNAKITYSISKTSKNN 1703

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                               +F I+  +G + T+ +L+ E    Y + V+A D    V+  
Sbjct: 1704 F---------------YTSIFHINPATGEITTKENLNFENKEHYEMSVQAEDGGGLVAQ- 1747

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
                + + + I D NDN P F++  Y  S+ E+  V  N  +  + ATD D G N+ I Y
Sbjct: 1748 ----SKVLIEITDVNDNVPVFTQAVYKASISENSPV--NTTVLYVNATDKDEGINAQIVY 1801

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            +     ++  F +DS +G    + T   LD E+   Y + I A D GSP  S+   + ++
Sbjct: 1802 SF-SKTSENSFHLDSSTGRFYRIVTKSALDREKTALYNITIVATDKGSPQLSSRKFIRLD 1860

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            I DVNDN P F  S     + EN   G SI R+QA D D G NA++ Y+++  D   N D
Sbjct: 1861 ISDVNDNPPVFMKSKDVAYLPENNLPGSSIYRIQASDLDTGDNAKVIYSISSMD---NED 1917

Query: 307  LPIT----IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
             PI+    I+  +G +Y     D E   ++Q+ +TA+DGG+P RS TA            
Sbjct: 1918 FPISSYFSINIETGVLYAQRSFDYEQVKEFQIQITASDGGNPVRSGTALIRIAVTDANDN 1977

Query: 363  XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422
               F    Y+V ++E+ P  + V+T+ ATD DE           N   R +  + +    
Sbjct: 1978 LPVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQSYRLSDNQYFRLNEKTNSDLSK 2037

Query: 423  ---ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTAS 477
               + + +PLD + +  + L ++A+D G   R+ TA+++I +TD+N+  PVF    Y  S
Sbjct: 2038 TPELVLEKPLDRETQSIHELILTASDGGNPLRTGTALIRIIVTDSNDNLPVFTQEVYKVS 2097

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ------TG 531
            + E+API ++V++++ATD D G NAQITYS+S    N     +   F INP         
Sbjct: 2098 ISENAPINSSVIILTATDKDEGTNAQITYSISKTSENN---FYTSVFNINPVIYYKIVNT 2154

Query: 532  AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
             +   K LDRET   + L +TA DGG P  + T  + I V D NDN PVF + +Y  +I 
Sbjct: 2155 ELMLEKPLDRETQKDHELILTASDGGDPVKTGTAIIRIIVTDANDNLPVFTKAVYKVSIS 2214

Query: 592  EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA 651
            E+  + +SV  V ATD D G N +I Y    K      F I+  +GV+   ++ D E   
Sbjct: 2215 ENIPINSSVLHVNATDRDEGTNAQITYSFI-KTSVSSYFSINIETGVLYAQRSFDYEQHK 2273

Query: 652  THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP-VFESDCLTFYISENSPIGTTIGEIR 710
               +   A D G P  SS   + I+I D ND+ P +         ISEN+PI +T+  + 
Sbjct: 2274 EFAMHVQAKDNGYPSLSSNATLIIRIIDQNDNAPKILYPSTENMSISENTPINSTVLRVN 2333

Query: 711  AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770
            A D DEG NA + YS      ++  +          E+ T   L+YE+ R  YE+ ++A 
Sbjct: 2334 ASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEIKTNNLLNYEAIRD-YEISVQAK 2392

Query: 771  SPPLW-NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD 825
                +    ++ + +TDVNDN PV           ++  P     R+ A D D+ D
Sbjct: 2393 DGGGFVAHSKILVEITDVNDNPPVFIKSAYTIYLPENNLPGATIYRIHALDLDMGD 2448



 Score =  369 bits (909), Expect = e-100
 Identities = 273/894 (30%), Positives = 436/894 (48%), Gaps = 65/894 (7%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I V D ND+ PVF  Q Y+ S+ E A   +TV  + ATD+D G N  + Y+      + 
Sbjct: 1535 RIIVTDYNDNVPVFTQQVYKISISESAPINSTVTVVTATDKDDGTNGHITYSFSRTAENA 1594

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             + +               +F I+  +G + T+ S    +    +     +D  +P+   
Sbjct: 1595 FHTQ---------------MFNINPANGEIKTKVSNINTEDFPVSPYFSTSDGGNPLR-- 1637

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             + TA I + + D NDN P F+++ Y VSV E+  +    +I  + ATD D G N+ I Y
Sbjct: 1638 -TGTALIRIIVTDSNDNLPVFTQEVYKVSVSENAPINSTVII--LTATDKDEGTNAKITY 1694

Query: 190  AIIGGNTQ----MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
            +I   +        F I+  +G+++  + L++E    Y + ++A+DGG     +  ++LI
Sbjct: 1695 SISKTSKNNFYTSIFHINPATGEITTKENLNFENKEHYEMSVQAEDGGGLVAQS--KVLI 1752

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
             I DVNDN P F  ++++ S+SEN P+  +++ V A D DEG+NA++ Y+ + K    + 
Sbjct: 1753 EITDVNDNVPVFTQAVYKASISENSPVNTTVLYVNATDKDEGINAQIVYSFS-KTSENSF 1811

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
             L  +   R   + T   LDRE  A Y + + ATD G P  S+                 
Sbjct: 1812 HLDSSTG-RFYRIVTKSALDREKTALYNITIVATDKGSPQLSSRKFIRLDISDVNDNPPV 1870

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRGRFSITSQNG---- 419
            FM  +    L E+  PG+ +  + A+D D  DN ++ Y I+  +    F I+S       
Sbjct: 1871 FMKSKDVAYLPENNLPGSSIYRIQASDLDTGDNAKVIYSISSMDNED-FPISSYFSINIE 1929

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTAS 477
             G++   +  D++Q + + + ++A+D G   RS TA+++I +TDAN+  PVF    Y  S
Sbjct: 1930 TGVLYAQRSFDYEQVKEFQIQITASDGGNPVRSGTALIRIAVTDANDNLPVFTQEVYKVS 1989

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            + E+ PI +TVL V+ATD D G NAQ +Y LS    N+    +++      +T  +   K
Sbjct: 1990 ISENIPINSTVLTVNATDRDEGTNAQ-SYRLSD---NQYFRLNEKTNSDLSKTPELVLEK 2045

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
             LDRET S + L +TA DGG P  + T  + I V D NDN PVF Q++Y  +I E+A + 
Sbjct: 2046 PLDRETQSIHELILTASDGGNPLRTGTALIRIIVTDSNDNLPVFTQEVYKVSISENAPIN 2105

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREE---GSFVIDPAS--GVIRTN----KALDRE 648
            +SV  + ATD D G N +I Y +            F I+P     ++ T     K LDRE
Sbjct: 2106 SSVIILTATDKDEGTNAQITYSISKTSENNFYTSVFNINPVIYYKIVNTELMLEKPLDRE 2165

Query: 649  SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
            +   H+L   A DGG P ++ T I+ I + D ND+ PVF        ISEN PI +++  
Sbjct: 2166 TQKDHELILTASDGGDPVKTGTAIIRIIVTDANDNLPVFTKAVYKVSISENIPINSSVLH 2225

Query: 709  IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768
            + A D DEG NA + YS      S+ FS+    G     L      DYE   K++ + ++
Sbjct: 2226 VNATDRDEGTNAQITYSFIKTSVSSYFSINIETGV----LYAQRSFDYEQ-HKEFAMHVQ 2280

Query: 769  AAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDAD-- 822
            A     P L ++  + I + D NDNAP +        +  +  P+     RV A D D  
Sbjct: 2281 AKDNGYPSLSSNATLIIRIIDQNDNAPKILYPSTENMSISENTPINSTVLRVNASDMDEG 2340

Query: 823  ----VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
                +T       ++  +A++  +N T+G +  +  LN    +   + V   DG
Sbjct: 2341 TNAQITYSFSRTSVNSLHASMFSINPTSGEIKTNNLLNYEAIRDYEISVQAKDG 2394



 Score =  361 bits (888), Expect = 2e-97
 Identities = 267/910 (29%), Positives = 434/910 (47%), Gaps = 59/910 (6%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I + D NDH P+F  + Y+ S+ E     TTVL + ATD+D G NA++ Y++   + D+
Sbjct: 1422 RIAITDVNDHIPMFTQEVYKVSISESIPINTTVLQVNATDKDEGVNAQITYSLIRTSGDS 1481

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD- 128
            L                   F I+  SG + T+ +L+ E    Y + V+A D A+   + 
Sbjct: 1482 L---------------ASATFSINPASGEIKTKRNLNFEVQKHYEMSVEAKDGATDGGNP 1526

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            + + TA + + + D NDN P F+++ Y +S+ E   +  N  +  + ATD D G N  I 
Sbjct: 1527 KRTGTALLRIIVTDYNDNVPVFTQQVYKISISESAPI--NSTVTVVTATDKDDGTNGHIT 1584

Query: 189  YAII-----GGNTQMQFSIDSLSGD----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239
            Y+         +TQM F+I+  +G+    VS + T D+  V  Y       DGG+P R+ 
Sbjct: 1585 YSFSRTAENAFHTQM-FNINPANGEIKTKVSNINTEDFP-VSPY---FSTSDGGNPLRTG 1639

Query: 240  TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
            T  + I + D NDN P F   +++ SVSEN PI  +++ + A D DEG NA++TY+++  
Sbjct: 1640 TALIRIIVTDSNDNLPVFTQEVYKVSVSENAPINSTVIILTATDKDEGTNAKITYSISKT 1699

Query: 300  DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
                       I+P +G + T   L+ E +  Y++ V A DGG     A +         
Sbjct: 1700 SKNNFYTSIFHINPATGEITTKENLNFENKEHYEMSVQAEDGGG--LVAQSKVLIEITDV 1757

Query: 360  XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT-RGRFSITSQN 418
                  F    Y+  ++E+ P  T V+ + ATD DE        +   T    F + S  
Sbjct: 1758 NDNVPVFTQAVYKASISENSPVNTTVLYVNATDKDEGINAQIVYSFSKTSENSFHLDSST 1817

Query: 419  GRGL-ITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYT 475
            GR   I     LD ++   Y +T+ ATD G    S    ++++I+D N+  PVF  +   
Sbjct: 1818 GRFYRIVTKSALDREKTALYNITIVATDKGSPQLSSRKFIRLDISDVNDNPPVFMKSKDV 1877

Query: 476  ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
            A + E+   G+++  + A+D D G NA++ YS+SS + NE        F IN +TG +  
Sbjct: 1878 AYLPENNLPGSSIYRIQASDLDTGDNAKVIYSISS-MDNEDFPI-SSYFSINIETGVLYA 1935

Query: 536  NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
             +  D E +  + + +TA DGG P  S T  + I+V D NDN PVF Q++Y  +I E+  
Sbjct: 1936 QRSFDYEQVKEFQIQITASDGGNPVRSGTALIRIAVTDANDNLPVFTQEVYKVSISENIP 1995

Query: 596  VGTSVSQVGATDADVGLNGRIHYELDPKD----REEGSFVIDPASGVIRTNKALDRESVA 651
            + ++V  V ATD D G N +  Y L         E+ +  +     ++   K LDRE+ +
Sbjct: 1996 INSTVLTVNATDRDEGTNAQ-SYRLSDNQYFRLNEKTNSDLSKTPELV-LEKPLDRETQS 2053

Query: 652  THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711
             H+L   A DGG P ++ T ++ I + D ND+ PVF  +     ISEN+PI +++  + A
Sbjct: 2054 IHELILTASDGGNPLRTGTALIRIIVTDSNDNLPVFTQEVYKVSISENAPINSSVIILTA 2113

Query: 712  HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP-----RKKYELV 766
             D DEG NA + YSI    ++N ++            +   +L  E P     +K +EL+
Sbjct: 2114 TDKDEGTNAQITYSISKTSENNFYTSVFNINPVIYYKIVNTELMLEKPLDRETQKDHELI 2173

Query: 767  IRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPAYDAD 822
            + A+    P       + I+VTD NDN PV     +   +  +  P+      V A D D
Sbjct: 2174 LTASDGGDPVKTGTAIIRIIVTDANDNLPVFTK-AVYKVSISENIPINSSVLHVNATDRD 2232

Query: 823  --VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAM 879
                 ++ Y  +  + ++   +N  TG +      +    K   M V   D G   + + 
Sbjct: 2233 EGTNAQITYSFIKTSVSSYFSINIETGVLYAQRSFDYEQHKEFAMHVQAKDNGYPSLSSN 2292

Query: 880  MQLSVRLITE 889
              L +R+I +
Sbjct: 2293 ATLIIRIIDQ 2302



 Score =  327 bits (804), Expect = 2e-87
 Identities = 271/908 (29%), Positives = 425/908 (46%), Gaps = 82/908 (9%)

Query: 8    HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
            H ++N+ D ND++P+F+   Y A + E    G+++  + A D D G NA++ Y+I    A
Sbjct: 873  HIRLNISDVNDNAPIFKKSTYVAYLSENNLPGSSIYRINAYDPDTGDNAKIIYSI----A 928

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
             T N +D           +   F I+  +G L  + S D E    + + + A D  SP  
Sbjct: 929  GT-NIKD---------IAISSYFSINIETGVLYAQRSFDYEHDKEFQIGITARDHGSP-- 976

Query: 128  DRLSSTATIHVNIIDD--NDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
              LSS  T+ ++IID   NDN P+FS++ Y V + E+  V  N  +  + ATD D G N+
Sbjct: 977  -SLSSNTTLVIHIIDHDANDNIPEFSKEVYKVKMSENTPV--NTTVLSVDATDKDEGLNA 1033

Query: 186  AIRYAII-GGNTQMQ---FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
             I Y+     + Q+    F I+  SG ++  + LD+E V+SY + I A DGG       T
Sbjct: 1034 QITYSFSKTSDNQLHTGTFDINPTSGKITTKRDLDFESVQSYEIAIEAMDGGGFVAQ--T 1091

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
            ++LI I D NDNAP    +     + E+   G  I  ++ +D D G N E+     D   
Sbjct: 1092 KVLIEIIDENDNAPEISIASLSAPIPEDSMPGTVIALIKVHDQDTGRNGEV-----DCQI 1146

Query: 302  TGNVDLPI-TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
             G     I +   R   + T+  LDRE    Y + + ATD G P  S+T +         
Sbjct: 1147 LGAAPFQIVSSSSRYYRIITASFLDREKVPWYNITILATDKGSPELSSTKSIKLDLSDVN 1206

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT-------RGRFS 413
                 F    Y   L E+  PG+ +  + A D D  N      +  NT          FS
Sbjct: 1207 DNPPVFSKPTYVAYLPENNLPGSSIYRIQAFDFDSGNNAKVVYSILNTYIQDIPVSAYFS 1266

Query: 414  ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAP-VF 469
            I   +  G++   +  D++Q + + + ++A DSG     S+  ++ I I D N+ AP + 
Sbjct: 1267 INVVS--GVLYAQRSFDYEQHQMFSMEITARDSGSPPLNSNITLI-IYIIDQNDNAPEIL 1323

Query: 470  ENAPY--TASVFEDAPI----GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523
              +P    +S+FE  P+    G+ +  V A D+D G N+ ++Y     +S+ +       
Sbjct: 1324 YPSPNGGGSSLFEMVPLASEQGSLITKVIAVDADSGHNSWLSYHF-IPMSDPS------P 1376

Query: 524  FVINPQTGAI-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582
            F IN  TG I T  K LDRE +  + L +TA DGG P  + T  + I++ DVND+ P+F 
Sbjct: 1377 FSINQYTGEIRTCQKPLDRENLKIHKLLLTAFDGGNPVRTGTALIRIAITDVNDHIPMFT 1436

Query: 583  QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL---DPKDREEGSFVIDPASGVI 639
            Q++Y  +I E   + T+V QV ATD D G+N +I Y L           +F I+PASG I
Sbjct: 1437 QEVYKVSISESIPINTTVLQVNATDKDEGVNAQITYSLIRTSGDSLASATFSINPASGEI 1496

Query: 640  RTNKALDRESVATHDL----KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695
            +T + L+ E    +++    K  A DGG P ++ T ++ I + D ND+ PVF        
Sbjct: 1497 KTKRNLNFEVQKHYEMSVEAKDGATDGGNPKRTGTALLRIIVTDYNDNVPVFTQQVYKIS 1556

Query: 696  ISENSPIGTTIGEIRAHDPDEGPNAVVHYSI----KGGDDSNSFSLETRQGSDKAELVTM 751
            ISE++PI +T+  + A D D+G N  + YS     +    +  F++    G  K ++  +
Sbjct: 1557 ISESAPINSTVTVVTATDKDDGTNGHITYSFSRTAENAFHTQMFNINPANGEIKTKVSNI 1616

Query: 752  VDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811
               D+  P   Y       +P       + I+VTD NDN PV    ++   +  +  P+ 
Sbjct: 1617 NTEDF--PVSPYFSTSDGGNPLRTGTALIRIIVTDSNDNLPVFTQ-EVYKVSVSENAPIN 1673

Query: 812  PFGRV-PAYDAD--VTDKLQYRI--LSGNN--ANLILLNETTGSMTLSPQLNTNVPKLAT 864
                +  A D D     K+ Y I   S NN   ++  +N  TG +T    LN    +   
Sbjct: 1674 STVIILTATDKDEGTNAKITYSISKTSKNNFYTSIFHINPATGEITTKENLNFENKEHYE 1733

Query: 865  MEVSVTDG 872
            M V   DG
Sbjct: 1734 MSVQAEDG 1741



 Score =  320 bits (785), Expect = 5e-85
 Identities = 267/934 (28%), Positives = 431/934 (46%), Gaps = 89/934 (9%)

Query: 12   NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT-----IELVT 66
            +V D ND+ P+F  + Y  S+ E    G+ +  + A+D+D GKNA++ Y      +E ++
Sbjct: 608  SVDDINDNPPLFTEELYFFSIAENILPGSLIFQVSASDKDSGKNAQLLYALLESYVEGMS 667

Query: 67   AD---TLNPE--------------DAXXXXXXXXXXVQD------VFRIDGRSGA----L 99
                 ++NP+              DA            D      +F +D  SG     L
Sbjct: 668  VSHFISINPDSGNVGHLVTKLRAVDADAGYNAWLTYEMDPVSNTTLFSVDSYSGENTYKL 727

Query: 100  LTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKT----Y 155
            +T   LDREK + Y + V  TD  +P    LS+  T++V + D NDN P F + T    Y
Sbjct: 728  VTVGKLDREKSSSYNITVTVTDSGTPP---LSTQKTLYVEVSDLNDNPPTFEKCTNKEVY 784

Query: 156  TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG-GNTQMQ---FSIDSLSGDVSL 211
             V + E+  +  N  + ++ ATD D G NS I Y+     + Q+    F I+  +G++  
Sbjct: 785  KVRISENSPI--NSTVIRVNATDKDEGLNSQITYSFSKTSDNQLYTSIFDINPTNGEIRT 842

Query: 212  VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271
               LD E    Y + I + D GSP  S    + +NI DVNDNAP F  S +   +SEN  
Sbjct: 843  TSFLDRENTSQYNITILSTDRGSPKLSTVKHIRLNISDVNDNAPIFKKSTYVAYLSENNL 902

Query: 272  IGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NVDLPITIDPRSGWVYTSGQLDRETQA 330
             G SI R+ AYD D G NA++ Y++   +     +    +I+  +G +Y     D E   
Sbjct: 903  PGSSIYRINAYDPDTGDNAKIIYSIAGTNIKDIAISSYFSINIETGVLYAQRSFDYEHDK 962

Query: 331  KYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX--XFMPGQYEVELAEDEPPGTPVVTL 388
            ++Q+ +TA D G P  S+  T                F    Y+V+++E+ P  T V+++
Sbjct: 963  EFQIGITARDHGSPSLSSNTTLVIHIIDHDANDNIPEFSKEVYKVKMSENTPVNTTVLSV 1022

Query: 389  TATDADE--DNRLHYEI--TGGNT--RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
             ATD DE  + ++ Y    T  N    G F I   +G+  IT  + LDF+  + Y + + 
Sbjct: 1023 DATDKDEGLNAQITYSFSKTSDNQLHTGTFDINPTSGK--ITTKRDLDFESVQSYEIAIE 1080

Query: 443  ATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502
            A D GG      V I I D N+ AP    A  +A + ED+  GT + ++   D D G N 
Sbjct: 1081 AMDGGGFVAQTKVLIEIIDENDNAPEISIASLSAPIPEDSMPGTVIALIKVHDQDTGRNG 1140

Query: 503  QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
            ++   +      + V+   + +        I T   LDRE +  Y +T+ A D G P LS
Sbjct: 1141 EVDCQILGAAPFQIVSSSSRYY-------RIITASFLDREKVPWYNITILATDKGSPELS 1193

Query: 563  DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE-LD 621
             T  +++ + DVNDN PVF +  Y A + E+ L G+S+ ++ A D D G N ++ Y  L+
Sbjct: 1194 STKSIKLDLSDVNDNPPVFSKPTYVAYLPENNLPGSSIYRIQAFDFDSGNNAKVVYSILN 1253

Query: 622  PKDRE---EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678
               ++      F I+  SGV+   ++ D E      ++  A D G+PP +S + + I I 
Sbjct: 1254 TYIQDIPVSAYFSINVVSGVLYAQRSFDYEQHQMFSMEITARDSGSPPLNSNITLIIYII 1313

Query: 679  DINDSPP--VFES-----DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD 731
            D ND+ P  ++ S       L   +   S  G+ I ++ A D D G N+ + Y      D
Sbjct: 1314 DQNDNAPEILYPSPNGGGSSLFEMVPLASEQGSLITKVIAVDADSGHNSWLSYHFIPMSD 1373

Query: 732  SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVN 788
             + FS+    G  +        LD E+  K ++L++ A    +P       + I +TDVN
Sbjct: 1374 PSPFSINQYTGEIR---TCQKPLDREN-LKIHKLLLTAFDGGNPVRTGTALIRIAITDVN 1429

Query: 789  DNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRIL--SGNN--ANLIL 841
            D+ P+    ++   +  +  P+     +V A D D  V  ++ Y ++  SG++  +    
Sbjct: 1430 DHIPMFTQ-EVYKVSISESIPINTTVLQVNATDKDEGVNAQITYSLIRTSGDSLASATFS 1488

Query: 842  LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE 875
            +N  +G +     LN  V K   M V   DG  +
Sbjct: 1489 INPASGEIKTKRNLNFEVQKHYEMSVEAKDGATD 1522



 Score =  315 bits (773), Expect = 1e-83
 Identities = 237/785 (30%), Positives = 375/785 (47%), Gaps = 57/785 (7%)

Query: 145  DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS 204
            ++Y +    ++ +S++ D S     ++ K++A DAD G N+ + Y +   +    FS+DS
Sbjct: 660  ESYVEGMSVSHFISINPD-SGNVGHLVTKLRAVDADAGYNAWLTYEMDPVSNTTLFSVDS 718

Query: 205  LSGD----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF--- 257
             SG+    +  V  LD E+  SY + +   D G+P  S    L + + D+NDN P F   
Sbjct: 719  YSGENTYKLVTVGKLDREKSSSYNITVTVTDSGTPPLSTQKTLYVEVSDLNDNPPTFEKC 778

Query: 258  -YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316
                +++  +SEN PI  +++RV A D DEG+N+++TY+ +             I+P +G
Sbjct: 779  TNKEVYKVRISENSPINSTVIRVNATDKDEGLNSQITYSFSKTSDNQLYTSIFDINPTNG 838

Query: 317  WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376
             + T+  LDRE  ++Y + + +TD G P  S                  F    Y   L+
Sbjct: 839  EIRTTSFLDRENTSQYNITILSTDRGSPKLSTVKHIRLNISDVNDNAPIFKKSTYVAYLS 898

Query: 377  EDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTR-----GRFSITSQNGRGLITVAQPL 429
            E+  PG+ +  + A D D  DN ++ Y I G N +       FSI  +   G++   +  
Sbjct: 899  ENNLPGSSIYRINAYDPDTGDNAKIIYSIAGTNIKDIAISSYFSINIET--GVLYAQRSF 956

Query: 430  DFKQERRYVLTVSATDSGGRS----DTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
            D++ ++ + + ++A D G  S     T ++ I   DAN+  P F    Y   + E+ P+ 
Sbjct: 957  DYEHDKEFQIGITARDHGSPSLSSNTTLVIHIIDHDANDNIPEFSKEVYKVKMSENTPVN 1016

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
            TTVL V ATD D G+NAQITYS S    N+    H   F INP +G ITT + LD E++ 
Sbjct: 1017 TTVLSVDATDKDEGLNAQITYSFSKTSDNQL---HTGTFDINPTSGKITTKRDLDFESVQ 1073

Query: 546  GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
             Y + + A DGG       T V I ++D NDN P       +A I ED++ GT ++ +  
Sbjct: 1074 SYEIAIEAMDGG--GFVAQTKVLIEIIDENDNAPEISIASLSAPIPEDSMPGTVIALIKV 1131

Query: 606  TDADVGLNGRIHYELDPKDREEGSF-VIDPASGVIR--TNKALDRESVATHDLKAVAIDG 662
             D D G NG    E+D +      F ++  +S   R  T   LDRE V  +++  +A D 
Sbjct: 1132 HDQDTGRNG----EVDCQILGAAPFQIVSSSSRYYRIITASFLDREKVPWYNITILATDK 1187

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
            G+P  SST  + + + D+ND+PPVF       Y+ EN+  G++I  I+A D D G NA V
Sbjct: 1188 GSPELSSTKSIKLDLSDVNDNPPVFSKPTYVAYLPENNLPGSSIYRIQAFDFDSGNNAKV 1247

Query: 723  HYSIKGG--DD---SNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIR-AASPPLW 775
             YSI      D   S  FS+    G     L      DYE  +    E+  R + SPPL 
Sbjct: 1248 VYSILNTYIQDIPVSAYFSINVVSG----VLYAQRSFDYEQHQMFSMEITARDSGSPPLN 1303

Query: 776  NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG--------RVPAYDADV--TD 825
            +++ + I + D NDNAP +  +          F + P          +V A DAD     
Sbjct: 1304 SNITLIIYIIDQNDNAPEIL-YPSPNGGGSSLFEMVPLASEQGSLITKVIAVDADSGHNS 1362

Query: 826  KLQYRILSGNNANLILLNETTGSM-TLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884
             L Y  +  ++ +   +N+ TG + T    L+    K+  + ++  DG N ++    L  
Sbjct: 1363 WLSYHFIPMSDPSPFSINQYTGEIRTCQKPLDRENLKIHKLLLTAFDGGNPVRTGTALIR 1422

Query: 885  RLITE 889
              IT+
Sbjct: 1423 IAITD 1427



 Score =  310 bits (760), Expect = 5e-82
 Identities = 203/626 (32%), Positives = 325/626 (51%), Gaps = 42/626 (6%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++++ D ND+ PVF   +  A + E    G+++  ++A+D D G NA+V Y+I      +
Sbjct: 1858 RLDISDVNDNPPVFMKSKDVAYLPENNLPGSSIYRIQASDLDTGDNAKVIYSIS-----S 1912

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            ++ ED           +   F I+  +G L  + S D E+V  + + + A+D  +PV   
Sbjct: 1913 MDNED---------FPISSYFSINIETGVLYAQRSFDYEQVKEFQIQITASDGGNPVR-- 1961

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             S TA I + + D NDN P F+++ Y VS+ E+I +  N  +  + ATD D G N A  Y
Sbjct: 1962 -SGTALIRIAVTDANDNLPVFTQEVYKVSISENIPI--NSTVLTVNATDRDEGTN-AQSY 2017

Query: 190  AIIGGN----TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
             +         +   S  S + ++ L K LD E    + L++ A DGG+P R+ T  + I
Sbjct: 2018 RLSDNQYFRLNEKTNSDLSKTPELVLEKPLDRETQSIHELILTASDGGNPLRTGTALIRI 2077

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY----TMTDKDY 301
             + D NDN P F   +++ S+SEN PI  S++ + A D DEG NA++TY    T  +  Y
Sbjct: 2078 IVTDSNDNLPVFTQEVYKVSISENAPINSSVIILTATDKDEGTNAQITYSISKTSENNFY 2137

Query: 302  TG--NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
            T   N++  I     +  +     LDRETQ  ++L++TA+DGGDP ++ TA         
Sbjct: 2138 TSVFNINPVIYYKIVNTELMLEKPLDRETQKDHELILTASDGGDPVKTGTAIIRIIVTDA 2197

Query: 360  XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQ 417
                  F    Y+V ++E+ P  + V+ + ATD DE  + ++ Y     +    FSI  +
Sbjct: 2198 NDNLPVFTKAVYKVSISENIPINSSVLHVNATDRDEGTNAQITYSFIKTSVSSYFSINIE 2257

Query: 418  NGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAP-VFENAPY 474
               G++   +  D++Q + + + V A D+G    S  A + I I D N+ AP +   +  
Sbjct: 2258 T--GVLYAQRSFDYEQHKEFAMHVQAKDNGYPSLSSNATLIIRIIDQNDNAPKILYPSTE 2315

Query: 475  TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
              S+ E+ PI +TVL V+A+D D G NAQITYS S    N     H   F INP +G I 
Sbjct: 2316 NMSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVNSL---HASMFSINPTSGEIK 2372

Query: 535  TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
            TN LL+ E +  Y ++V A+DGG       + + + + DVNDN PVF +  YT  + E+ 
Sbjct: 2373 TNNLLNYEAIRDYEISVQAKDGG--GFVAHSKILVEITDVNDNPPVFIKSAYTIYLPENN 2430

Query: 595  LVGTSVSQVGATDADVGLNGRIHYEL 620
            L G ++ ++ A D D+G N ++ Y +
Sbjct: 2431 LPGATIYRIHALDLDMGDNAKVIYSI 2456



 Score =  272 bits (666), Expect = 1e-70
 Identities = 202/624 (32%), Positives = 303/624 (48%), Gaps = 68/624 (10%)

Query: 12  NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71
           +V D ND+ PVF    Y+ S+ E A  GT V  L ATD D+GKN E  Y         L 
Sbjct: 88  HVEDVNDNPPVFNQSVYQCSITENAPKGTLVAKLFATDMDVGKNGETSYEF-----SKLV 142

Query: 72  PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131
           PE            +  +F +D  +G +  +  LD EK   Y VL+ A D          
Sbjct: 143 PE-----------RMLSLFSLDKYTGEVWVKGELDYEKSNTYEVLIDALD---------- 181

Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191
                +V ++D NDN P+ +  + ++ V ED   T   ++A I+  D D G N  +    
Sbjct: 182 -----NVTVVDVNDNAPEMTVTSLSLPVPED--ATHGTIVAIIRVRDRDSGNNGKVN--- 231

Query: 192 IGGNTQMQFSID-SLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
              +T   F I+ + SGD SL+    LD E+   Y++VI A+D G PS S +  + + + 
Sbjct: 232 CYSSTPTLFKINPAFSGDFSLIVNSPLDREKKSEYQVVITAKDEGYPSLSVSMTINVEVS 291

Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
           DVNDNAP F  S     + EN P G  I  V A D+D   NA L  +    D + +V   
Sbjct: 292 DVNDNAPLFQQSSDTIFIRENNPPGSHIYTVSASDSDINDNAPLFIS----DNSNSVSAM 347

Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
           +   P+S        LDRE +++YQ+++TA D G P  S + T              F  
Sbjct: 348 LVTAPKSAQPAVDAPLDRENKSEYQVVITAKDEGSPSLSISMTINVEISDVNDNAPLFQQ 407

Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITS----QNGRGLIT 424
               + + E+ PPG+ +  ++A+D+D         TG N+   +S+ S       + L+ 
Sbjct: 408 TADTIFIRENNPPGSQIYIVSASDSD---------TGQNSFITYSLKSPSKDNKSKSLVL 458

Query: 425 VA-QPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
           V  Q LD +++  ++LT++A D G   RS T  ++I + D N+ AP F +  Y  S+ E+
Sbjct: 459 VLNQALDREKQASHLLTLTAADCGTPKRSGTTQIRILVQDVNDNAPTFRHPIYRVSIPEN 518

Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
             +G+ ++V+ ATD D G N  I YS SS I + +V    Q F I    G +    LLD 
Sbjct: 519 YAVGSLIVVLKATDLDEGENGVIEYSFSS-IGSRSV---KQLFKIEKNNGEVHLKGLLDY 574

Query: 542 ETMSGYLLTVTAR-----DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
           E    Y + V        D G+P+LS T  +  SV D+NDN P+F ++LY  +I E+ L 
Sbjct: 575 ENKKYYEIHVQGNRWQTTDNGIPALSTTAYIYFSVDDINDNPPLFTEELYFFSIAENILP 634

Query: 597 GTSVSQVGATDADVGLNGRIHYEL 620
           G+ + QV A+D D G N ++ Y L
Sbjct: 635 GSLIFQVSASDKDSGKNAQLLYAL 658



 Score =  266 bits (652), Expect = 6e-69
 Identities = 211/714 (29%), Positives = 337/714 (47%), Gaps = 68/714 (9%)

Query: 174 IKATDADVGANSAIRYAII-----GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIR 228
           + A+D+D G NS I Y++      G       +I+  +G++ L + +   +  ++RL + 
Sbjct: 1   VSASDSDTGQNSFITYSLTESFIEGVPVSSYIAINPHAGEIRLTRPITEAEGDAFRLFVV 60

Query: 229 AQDGGSPSRSNTTQLLINIRD----------VNDNAPRFYTSLFQESVSENVPIGYSIVR 278
           A+D G P+ +  TQ++I+I+D          VNDN P F  S++Q S++EN P G  + +
Sbjct: 61  AEDHGEPAMTALTQIIISIKDSGFARTHVEDVNDNPPVFNQSVYQCSITENAPKGTLVAK 120

Query: 279 VQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA 338
           + A D D G N E +Y  +       + L  ++D  +G V+  G+LD E    Y++L+ A
Sbjct: 121 LFATDMDVGKNGETSYEFSKLVPERMLSL-FSLDKYTGEVWVKGELDYEKSNTYEVLIDA 179

Query: 339 TDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR 398
            D      + T                 +P      + ED   GT V  +   D D  N 
Sbjct: 180 LD------NVTVVDVNDNAPEMTVTSLSLP------VPEDATHGTIVAIIRVRDRDSGNN 227

Query: 399 LHYEITGGNTRGRFSITSQ-NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQI 457
                   +T   F I    +G   + V  PLD +++  Y + ++A D G  S +  + I
Sbjct: 228 GKVNCYS-STPTLFKINPAFSGDFSLIVNSPLDREKKSEYQVVITAKDEGYPSLSVSMTI 286

Query: 458 NI--TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515
           N+  +D N+ AP+F+ +  T  + E+ P G+ +  VSA+DSD+  NA +     S+ SN 
Sbjct: 287 NVEVSDVNDNAPLFQQSSDTIFIRENNPPGSHIYTVSASDSDINDNAPL---FISDNSNS 343

Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575
             A      V  P++     +  LDRE  S Y + +TA+D G PSLS +  + + + DVN
Sbjct: 344 VSA----MLVTAPKSAQPAVDAPLDRENKSEYQVVITAKDEGSPSLSISMTINVEISDVN 399

Query: 576 DNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA 635
           DN P+F+Q   T  I E+   G+ +  V A+D+D G N  I Y L    ++  S      
Sbjct: 400 DNAPLFQQTADTIFIRENNPPGSQIYIVSASDSDTGQNSFITYSLKSPSKDNKS-----K 454

Query: 636 SGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695
           S V+  N+ALDRE  A+H L   A D GTP +S T  + I ++D+ND+ P F        
Sbjct: 455 SLVLVLNQALDREKQASHLLTLTAADCGTPKRSGTTQIRILVQDVNDNAPTFRHPIYRVS 514

Query: 696 ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG-GDDSNSFSLETRQGSDKAELVTMVDL 754
           I EN  +G+ I  ++A D DEG N V+ YS    G  S     +  + + +  L  +  L
Sbjct: 515 IPENYAVGSLIVVLKATDLDEGENGVIEYSFSSIGSRSVKQLFKIEKNNGEVHLKGL--L 572

Query: 755 DYESPRKKYELVIRA--------ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKD 806
           DYE+ +K YE+ ++           P L     +   V D+NDN P+  +    F+  ++
Sbjct: 573 DYEN-KKYYEIHVQGNRWQTTDNGIPALSTTAYIYFSVDDINDNPPLFTEELYFFSIAEN 631

Query: 807 CFPVGPFGRVPAYDADVTDKLQYRILSGNNANLI--LLNETTGSMTLSPQLNTN 858
             P     +V A D D          SG NA L+  LL      M++S  ++ N
Sbjct: 632 ILPGSLIFQVSASDKD----------SGKNAQLLYALLESYVEGMSVSHFISIN 675



 Score =  264 bits (647), Expect = 2e-68
 Identities = 187/615 (30%), Positives = 297/615 (48%), Gaps = 47/615 (7%)

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
           +S + S  A  HV   D NDN P F++  Y  S+ E+       ++AK+ ATD DVG N 
Sbjct: 77  ISIKDSGFARTHVE--DVNDNPPVFNQSVYQCSITEN--APKGTLVAKLFATDMDVGKNG 132

Query: 186 AIRYA---IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
              Y    ++       FS+D  +G+V +   LDYE+  +Y ++I A D           
Sbjct: 133 ETSYEFSKLVPERMLSLFSLDKYTGEVWVKGELDYEKSNTYEVLIDALDN---------- 182

Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT-YTMTDKDY 301
             + + DVNDNAP    +     V E+   G  +  ++  D D G N ++  Y+ T   +
Sbjct: 183 --VTVVDVNDNAPEMTVTSLSLPVPEDATHGTIVAIIRVRDRDSGNNGKVNCYSSTPTLF 240

Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
             N   P      S  +  +  LDRE +++YQ+++TA D G P  S + T          
Sbjct: 241 KIN---PAFSGDFS--LIVNSPLDREKKSEYQVVITAKDEGYPSLSVSMTINVEVSDVND 295

Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD-EDNRLHYEITGGNTRGRFSITSQNGR 420
               F      + + E+ PPG+ + T++A+D+D  DN   +     N+     +T+    
Sbjct: 296 NAPLFQQSSDTIFIRENNPPGSHIYTVSASDSDINDNAPLFISDNSNSVSAMLVTAPKS- 354

Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYAPVFENAPYTASV 478
               V  PLD + +  Y + ++A D G  S +  + IN  I+D N+ AP+F+    T  +
Sbjct: 355 AQPAVDAPLDRENKSEYQVVITAKDEGSPSLSISMTINVEISDVNDNAPLFQQTADTIFI 414

Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
            E+ P G+ + +VSA+DSD G N+ ITYSL S   +              ++  +  N+ 
Sbjct: 415 RENNPPGSQIYIVSASDSDTGQNSFITYSLKSPSKDN-----------KSKSLVLVLNQA 463

Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
           LDRE  + +LLT+TA D G P  S TT + I V DVNDN P F+  +Y  +I E+  VG+
Sbjct: 464 LDREKQASHLLTLTAADCGTPKRSGTTQIRILVQDVNDNAPTFRHPIYRVSIPENYAVGS 523

Query: 599 SVSQVGATDADVGLNGRIHYELDP--KDREEGSFVIDPASGVIRTNKALDRESVATHDL- 655
            +  + ATD D G NG I Y          +  F I+  +G +     LD E+   +++ 
Sbjct: 524 LIVVLKATDLDEGENGVIEYSFSSIGSRSVKQLFKIEKNNGEVHLKGLLDYENKKYYEIH 583

Query: 656 ----KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711
               +    D G P  S+T  ++  ++DIND+PP+F  +   F I+EN   G+ I ++ A
Sbjct: 584 VQGNRWQTTDNGIPALSTTAYIYFSVDDINDNPPLFTEELYFFSIAENILPGSLIFQVSA 643

Query: 712 HDPDEGPNAVVHYSI 726
            D D G NA + Y++
Sbjct: 644 SDKDSGKNAQLLYAL 658



 Score =  232 bits (568), Expect = 9e-59
 Identities = 218/797 (27%), Positives = 357/797 (44%), Gaps = 101/797 (12%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + V D ND++P+F+       +RE    G+ + T+ A+D DI  NA       L  +D  
Sbjct: 288 VEVSDVNDNAPLFQQSSDTIFIRENNPPGSHIYTVSASDSDINDNAP------LFISDNS 341

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           N   A                   +S      A LDRE  + Y V++ A D+ SP    L
Sbjct: 342 NSVSAMLVTAP-------------KSAQPAVDAPLDRENKSEYQVVITAKDEGSP---SL 385

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           S + TI+V I D NDN P F +   T+ + E+        I  + A+D+D G NS I Y+
Sbjct: 386 SISMTINVEISDVNDNAPLFQQTADTIFIRENNPPGSQIYI--VSASDSDTGQNSFITYS 443

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
           +   +   +    S S  + L + LD E+  S+ L + A D G+P RS TTQ+ I ++DV
Sbjct: 444 LKSPSKDNK----SKSLVLVLNQALDREKQASHLLTLTAADCGTPKRSGTTQIRILVQDV 499

Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
           NDNAP F   +++ S+ EN  +G  IV ++A D DEG N  + Y+ +    + +V     
Sbjct: 500 NDNAPTFRHPIYRVSIPENYAVGSLIVVLKATDLDEGENGVIEYSFSSIG-SRSVKQLFK 558

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLV-----TATDGGDPPRSATATXXXXXXXXXXXXXX 365
           I+  +G V+  G LD E +  Y++ V       TD G P  S TA               
Sbjct: 559 IEKNNGEVHLKGLLDYENKKYYEIHVQGNRWQTTDNGIPALSTTAYIYFSVDDINDNPPL 618

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV 425
           F    Y   +AE+  PG+ +  ++A+D D         +G N +  +++      G+ +V
Sbjct: 619 FTEELYFFSIAENILPGSLIFQVSASDKD---------SGKNAQLLYALLESYVEGM-SV 668

Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA-SVFEDAPI 484
           +              +S     G     + ++   DA        +A Y A   +E  P+
Sbjct: 669 SH------------FISINPDSGNVGHLVTKLRAVDA--------DAGYNAWLTYEMDPV 708

Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
             T L   + DS  G N     ++      ++ +++    V +  T  ++T K L     
Sbjct: 709 SNTTLF--SVDSYSGENTYKLVTVGKLDREKSSSYNITVTVTDSGTPPLSTQKTL----- 761

Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
               + V+  +   P+    T+ E+  V +++N P+                 ++V +V 
Sbjct: 762 ---YVEVSDLNDNPPTFEKCTNKEVYKVRISENSPI----------------NSTVIRVN 802

Query: 605 ATDADVGLNGRIHYELDPKDREE---GSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
           ATD D GLN +I Y        +     F I+P +G IRT   LDRE+ + +++  ++ D
Sbjct: 803 ATDKDEGLNSQITYSFSKTSDNQLYTSIFDINPTNGEIRTTSFLDRENTSQYNITILSTD 862

Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
            G+P  S+   + + I D+ND+ P+F+      Y+SEN+  G++I  I A+DPD G NA 
Sbjct: 863 RGSPKLSTVKHIRLNISDVNDNAPIFKKSTYVAYLSENNLPGSSIYRINAYDPDTGDNAK 922

Query: 722 VHYSIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWND 777
           + YSI G +  + + S       +   L      DYE   K++++ I A    SP L ++
Sbjct: 923 IIYSIAGTNIKDIAISSYFSINIETGVLYAQRSFDYEHD-KEFQIGITARDHGSPSLSSN 981

Query: 778 VR--VEILVTDVNDNAP 792
               + I+  D NDN P
Sbjct: 982 TTLVIHIIDHDANDNIP 998



 Score =  192 bits (467), Expect = 2e-46
 Identities = 160/552 (28%), Positives = 249/552 (45%), Gaps = 52/552 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + V+D ND++P   +      V E A+ GT V  ++  D+D G N +V       T   +
Sbjct: 183 VTVVDVNDNAPEMTVTSLSLPVPEDATHGTIVAIIRVRDRDSGNNGKVNCYSSTPTLFKI 242

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           NP                 F  D    +L+  + LDREK + Y V++ A D+  P    L
Sbjct: 243 NP----------------AFSGD---FSLIVNSPLDREKKSEYQVVITAKDEGYP---SL 280

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           S + TI+V + D NDN P F + + T+ + E+     +  I  + A+D+D+  N+ +  +
Sbjct: 281 SVSMTINVEVSDVNDNAPLFQQSSDTIFIRENNPPGSH--IYTVSASDSDINDNAPLFIS 338

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
               +          S   ++   LD E    Y++VI A+D GSPS S +  + + I DV
Sbjct: 339 DNSNSVSAMLVTAPKSAQPAVDAPLDRENKSEYQVVITAKDEGSPSLSISMTINVEISDV 398

Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
           NDNAP F  +     + EN P G  I  V A D+D G N+ +TY++              
Sbjct: 399 NDNAPLFQQTADTIFIRENNPPGSQIYIVSASDSDTGQNSFITYSLKSPSKDNK------ 452

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
              +S  +  +  LDRE QA + L +TA D G P RS T                F    
Sbjct: 453 --SKSLVLVLNQALDREKQASHLLTLTAADCGTPKRSGTTQIRILVQDVNDNAPTFRHPI 510

Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRG---RFSITSQNGRGLITV 425
           Y V + E+   G+ +V L ATD DE     + Y  +   +R     F I   NG   + +
Sbjct: 511 YRVSIPENYAVGSLIVVLKATDLDEGENGVIEYSFSSIGSRSVKQLFKIEKNNGE--VHL 568

Query: 426 AQPLDFKQERRYVLTV-----SATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASV 478
              LD++ ++ Y + V       TD+G    S TA +  ++ D N+  P+F    Y  S+
Sbjct: 569 KGLLDYENKKYYEIHVQGNRWQTTDNGIPALSTTAYIYFSVDDINDNPPLFTEELYFFSI 628

Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYS-LSSEISNEAVAHHDQQFVINPQTGAI--TT 535
            E+   G+ +  VSA+D D G NAQ+ Y+ L S +   +V+H      INP +G +    
Sbjct: 629 AENILPGSLIFQVSASDKDSGKNAQLLYALLESYVEGMSVSHF---ISINPDSGNVGHLV 685

Query: 536 NKLLDRETMSGY 547
            KL   +  +GY
Sbjct: 686 TKLRAVDADAGY 697



 Score = 81.8 bits (193), Expect = 2e-13
 Identities = 57/188 (30%), Positives = 94/188 (50%), Gaps = 26/188 (13%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +I V D ND++P F    Y  S+ E  + G+ ++ LKATD D G+N  +EY+   +    
Sbjct: 493 RILVQDVNDNAPTFRHPIYRVSIPENYAVGSLIVVLKATDLDEGENGVIEYSFSSI---- 548

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLV-----KATDQAS 124
                           V+ +F+I+  +G +  +  LD E    Y + V     + TD   
Sbjct: 549 ------------GSRSVKQLFKIEKNNGEVHLKGLLDYENKKYYEIHVQGNRWQTTDNGI 596

Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184
           P    LS+TA I+ ++ D NDN P F+E+ Y  S+ E+I      +I ++ A+D D G N
Sbjct: 597 PA---LSTTAYIYFSVDDINDNPPLFTEELYFFSIAENI--LPGSLIFQVSASDKDSGKN 651

Query: 185 SAIRYAII 192
           + + YA++
Sbjct: 652 AQLLYALL 659


>UniRef50_UPI00004D1B71 Cluster: SH3 adapter protein SPIN90
            (NCK-interacting protein with SH3 domain) (SH3 protein
            interacting with Nck, 90 kDa) (VacA-interacting protein,
            54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting
            protein) (Dia-interacting protein 1) (DIP-1).; n=1;
            Xenopus tropicalis|Rep: SH3 adapter protein SPIN90
            (NCK-interacting protein with SH3 domain) (SH3 protein
            interacting with Nck, 90 kDa) (VacA-interacting protein,
            54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting
            protein) (Dia-interacting protein 1) (DIP-1). - Xenopus
            tropicalis
          Length = 1171

 Score =  407 bits (1001), Expect = e-111
 Identities = 211/567 (37%), Positives = 309/567 (54%), Gaps = 41/567 (7%)

Query: 1356 WRFGGDGMLSFNPLLR-PIQLPWLNALSIRTRQRDAFVMSI----------QLKSGLLHY 1404
            ++F G  +LS++      I +PW   L+ RTR+ D  ++            QL SGL+ +
Sbjct: 8    YQFNGSSLLSWDFKNDVKISVPWFLGLAFRTRRADGVLLQAHAGQYTTILCQLVSGLISF 67

Query: 1405 SYNG-----ETMYLPMATLSDGAWHRIEIKWL----GTD----ISVTVDYGLRTVLMPML 1451
            S +        + L    ++DG WH ++++      G +    IS+ +DYG     + + 
Sbjct: 68   SVSRGSSRTSALLLDQMLVNDGKWHDLQMELRDVRSGRETRYVISINLDYGFYQDTVTV- 126

Query: 1452 ANKIQGQYIGKILIGGLDTTAGLLASDVGFFEGCIQDVRIGTAQS--LLNRPTVRENVRD 1509
             +++ G  +  + IGG+   +G      GF EGCIQ VR+G   S   L +P+   NV+ 
Sbjct: 127  GSELHGLRVKNLYIGGV---SGPREVQNGF-EGCIQGVRLGETPSGITLPKPSSALNVKP 182

Query: 1510 GCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPC---GAARCVPDQ 1566
            GC     C  + CP  S CV  W S +C C  G  G  C+  C+L PC   G  R  P  
Sbjct: 183  GCGVPNMCDSNPCPGNSSCVNEWMSYSCVCHPGYYGENCIDVCQLNPCENRGVCRHQPS- 241

Query: 1567 TPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKC 1626
             P GY+C C   +      C     ++CP GWWG + CGPC CDV +G+ P CNK NG+C
Sbjct: 242  APMGYTCECSKNHI--GRYCEHRLDQQCPKGWWGNATCGPCHCDVNKGFDPDCNKTNGQC 299

Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTP 1686
            +CKE HY+P+G+  CLPC CY  GS + +C+  TGQC+CRPGVIGR C+ C + +A+V+P
Sbjct: 300  NCKEFHYRPKGSETCLPCDCYPIGSSSRACDQETGQCYCRPGVIGRECNNCDSPFAQVSP 359

Query: 1687 NSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSGRATRTCDETKDVPWQDPDMF 1746
             SGCEV+YDGCP++   GVWWPRTKFG+     CP GS G A R CD+ K   W +PD+F
Sbjct: 360  -SGCEVIYDGCPKTLTAGVWWPRTKFGLPAAVPCPKGSLGAAIRHCDDVKG--WLEPDLF 416

Query: 1747 NCTTATFYQLRKQLHKIETGELTMNTFVGVRVAADLSTACANTPRLYGADVVVAEGILLE 1806
            NCT+  F +L   L  +E  E  +NT    ++A  L +      + +G DV +   +L  
Sbjct: 417  NCTSPAFVELSPMLDGLERNETELNTIEAKKLALRLRSVTDQMDQYFGNDVHITYRLLSY 476

Query: 1807 LMDYELRQAGLNLTHSQDKDYVRNLLKSTNTILNVEYEREWKRIRELTGHGAELLVQKFD 1866
            LM YE +Q G  LT +QD  +  NLLK+ ++IL +     W+ +     HG+  L+    
Sbjct: 477  LMQYENKQEGFGLTATQDAQFTENLLKTGSSILTLGNREHWEALLH-NEHGSAGLMNLLW 535

Query: 1867 EYIAVLAESQHDTYTSPFEIVTKDVVI 1893
            EY + LA++   TY +P  +VT +++I
Sbjct: 536  EYSSTLAKNMKLTYLNPVGLVTPNIII 562



 Score = 48.0 bits (109), Expect = 0.004
 Identities = 33/137 (24%), Positives = 68/137 (49%), Gaps = 15/137 (10%)

Query: 2195 SRTNPQCVHWST---LRGSGEWSRVGCHTEIDYDWSPYSEEPLLINCTCNHLSTFAVLVD 2251
            +R+ P CV W+    +   G W+   C  E+ Y  + +      + C C    T+ VL+D
Sbjct: 668  NRSKPVCVQWNQSEQVDPLGSWTVKDC--ELVYRNTTH------VRCHCPQFGTYGVLMD 719

Query: 2252 ---EVDVEFIPEPSLLESVTSYTAFSISLPLLLTSWAALCLIRGGAATVSNSIHKHLIFS 2308
                 D + +       ++ SYT+ SISL  L+ +++ L  ++ G  + +  IH ++  +
Sbjct: 720  GSHREDKQQLEGDLETLAIVSYTSLSISLAALVATFSILTFLK-GLKSNTRGIHSNIAVA 778

Query: 2309 VFMAELLYLIALKARTS 2325
            +F++EL++++ +    S
Sbjct: 779  LFLSELVFVLGINRTES 795



 Score = 38.3 bits (85), Expect = 3.0
 Identities = 13/34 (38%), Positives = 19/34 (55%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD 1350
            C S PC   + C + W +Y C C  G+ G++C D
Sbjct: 190  CDSNPCPGNSSCVNEWMSYSCVCHPGYYGENCID 223


>UniRef50_Q4SRY5 Cluster: Chromosome 18 SCAF14485, whole genome
            shotgun sequence; n=7; Euteleostomi|Rep: Chromosome 18
            SCAF14485, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 2244

 Score =  407 bits (1001), Expect = e-111
 Identities = 277/883 (31%), Positives = 448/883 (50%), Gaps = 54/883 (6%)

Query: 3    VPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
            V FC+   I + D ND++P F    Y++++      GT+V+ + A+D D G NA++EY+I
Sbjct: 1331 VGFCVVNVI-LTDINDNAPQFRAADYKSTIASDVPRGTSVVRISASDLDEGSNADIEYSI 1389

Query: 63   ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122
            E   AD  N              V++ F I   SG ++T+ SL   +   Y   V+A D 
Sbjct: 1390 E---ADVEN--------------VEENFEIHPTSGLIVTKESLIGLENELYAFFVRAKDT 1432

Query: 123  ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
             +P      S   +++ I+      P+F+E  Y  +V ED+ +     I  I+A  A   
Sbjct: 1433 GNPPQH---SVVQVNIRIVAPETPIPKFNEAQYRYTVAEDLPIGTE--IDVIQAESAQPL 1487

Query: 183  ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
              S ++ +    N    F +D  SG + L K+LD+E  + Y+ ++ +Q          + 
Sbjct: 1488 IYSLVKGSTPESNADEVFVVDRDSGALKLQKSLDHETTKWYQFLLHSQTKHENFDIVASV 1547

Query: 243  LL-INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
            ++ I ++DVNDN P F +  ++  V EN+P G  +++V+A D D G N ++ Y++  +  
Sbjct: 1548 IVNIQVKDVNDNKPVFESDPYEAVVVENLPSGTQVIQVRASDQDSGTNGQVIYSLDARQS 1607

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
            +  +     ++  +GWV T  +LDRE   +Y + V ATD GD  + AT T          
Sbjct: 1608 SEEISELFAVNSETGWVTTLKELDREKMQRYTIAVLATDQGDRIQHATGTRVEVTVADVN 1667

Query: 362  XXX-XFMPGQYEVELAEDEPPGTPVVT-LTATDADEDN---RLHYEITGGNTRGRFSITS 416
                 F    Y+  ++ED+PP + V+  L+ TDAD ++   +++Y ITGG+  G+F+I  
Sbjct: 1668 DNPPRFTAEIYKGTVSEDDPPPSGVIAILSTTDADSEDINKQVNYFITGGDPLGQFAIEH 1727

Query: 417  QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA 476
                  + V +PLD +++  Y+L ++A+D G  +  A V++ + DAN+ +P  E A Y+ 
Sbjct: 1728 IQNEWKVFVKKPLDREEKDNYLLNITASD-GIFTAKATVEVKVLDANDNSPQCEKALYSE 1786

Query: 477  SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
            SV E++P G  +L VSA+D+D+  NAQI Y L    S        + F I+  TG + T 
Sbjct: 1787 SVPENSPAGRLILQVSASDADIRSNAQIFYELQGAGS--------ELFTIDSDTGELKTL 1838

Query: 537  KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
            + LDRE    +   + A DGG        D+ + V DVNDN P F   LYT  + E+  +
Sbjct: 1839 QPLDREEQEEHRFKMRAVDGGGRYCE--ADIHVVVEDVNDNLPQFSADLYTVTVFENTEI 1896

Query: 597  GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
            GT V+++ A D DVG N  I Y L   D  +G F ID  +GVI   + LDRE  +T++L+
Sbjct: 1897 GTYVAKLLANDVDVGPNSNIIYSL--LDSADGFFSIDEQTGVISLERPLDRELQSTYELR 1954

Query: 657  AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
            A+A D G P  SS   V + + DIND+PPVFE    T  +SE+  +GT +  ++A   D 
Sbjct: 1955 ALASDQGLPRLSSVCQVVVSVLDINDNPPVFEHREYTATVSEDVSVGTQLLRVQAASRDT 2014

Query: 717  GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV--IRAASPPL 774
              N  + Y I  G++   FS++ R G    ++  +  LDYE+  + Y  V      SPPL
Sbjct: 2015 EANGEISYGIISGNEHGLFSVDPRTG----DIFVIQPLDYEASHEYYITVEATDGGSPPL 2070

Query: 775  WNDVRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRIL 832
             +   V I +TDVNDN PV     +  + +   +             D      ++Y I+
Sbjct: 2071 SDMATVNINLTDVNDNRPVFSQDVYTAVVSEDAELGKTVITVNAEDLDGPSHSHVRYSIV 2130

Query: 833  SGNNANLILLNETTGSMTLSPQLN---TNVPK-LATMEVSVTD 871
             GN  +   ++   G + ++ QL+    N PK  + ++++VTD
Sbjct: 2131 DGNQGSPFTIDSARGELKVAHQLDRERENRPKGTSVLQLTVTD 2173



 Score =  316 bits (776), Expect = 6e-84
 Identities = 236/815 (28%), Positives = 377/815 (46%), Gaps = 46/815 (5%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            F ID  +G +     LD E    Y + V+ATD  +       S   + + + D NDN P 
Sbjct: 981  FSIDFNTGVIHVIQPLDFETHPAYKLSVRATDSLTGAH----SDVFVDIILEDVNDNAPV 1036

Query: 150  FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG--GNTQMQFSIDSLSG 207
            F  K Y  +V E  SV    ++ ++ A D+D G N  + + ++   G +   F+ID  +G
Sbjct: 1037 FLSKAYHANVSE-ASVVGTRIL-QVDAKDSDTGNNQEVFFQLVEEKGESSDFFTIDRDTG 1094

Query: 208  DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
             +S  + LDYE++R + L +RA D G P+ S+   + I++ D+NDNAP F    +  ++S
Sbjct: 1095 TISTAQLLDYEEIRQHELRVRAVDRGVPALSSEVIVTIDVTDLNDNAPEFTQQTYNSTIS 1154

Query: 268  ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
            E  P G+ I +VQA DAD      L +  T    +GN DL  +ID  +G +  S      
Sbjct: 1155 ELAPRGHFITQVQASDADSSDKDNLLFFFT----SGNEDLNFSIDKHTGAILISNHRRVH 1210

Query: 328  TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387
             Q  Y L V+ +DG      ++A               F   ++ VEL E     TPV  
Sbjct: 1211 MQPFYNLSVSVSDG---VFRSSAAVLVTVIGANFHSPTFSQTEFVVELVEHSEIYTPVAE 1267

Query: 388  LTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS--A 443
              ATDADE    ++ Y+I     + +FS+   N  G I   + LD +     V+ +S  A
Sbjct: 1268 AKATDADEGIYGQIRYQIVNDFAKDKFSV---NENGEIFTLESLDRENNMEKVVPISLVA 1324

Query: 444  TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503
             D GG+    +V + +TD N+ AP F  A Y +++  D P GT+V+ +SA+D D G NA 
Sbjct: 1325 RDGGGKVGFCVVNVILTDINDNAPQFRAADYKSTIASDVPRGTSVVRISASDLDEGSNAD 1384

Query: 504  ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD 563
            I YS+ +++ N      ++ F I+P +G I T + L       Y   V A+D G P    
Sbjct: 1385 IEYSIEADVENV-----EENFEIHPTSGLIVTKESLIGLENELYAFFVRAKDTGNPPQHS 1439

Query: 564  TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK 623
               V I +V      P F +  Y   + ED  +GT +  + A  A   +   +     P+
Sbjct: 1440 VVQVNIRIVAPETPIPKFNEAQYRYTVAEDLPIGTEIDVIQAESAQPLIYSLVKGS-TPE 1498

Query: 624  DREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS----STVIVHIKIED 679
               +  FV+D  SG ++  K+LD E+   +      +   T  ++    ++VIV+I+++D
Sbjct: 1499 SNADEVFVVDRDSGALKLQKSLDHETTKWYQF---LLHSQTKHENFDIVASVIVNIQVKD 1555

Query: 680  INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLET 739
            +ND+ PVFESD     + EN P GT + ++RA D D G N  V YS+     S   S   
Sbjct: 1556 VNDNKPVFESDPYEAVVVENLPSGTQVIQVRASDQDSGTNGQVIYSLDARQSSEEISELF 1615

Query: 740  RQGSDKAELVTMVDLDYESPRKKYELVIRAASP----PLWNDVRVEILVTDVNDNAP-VM 794
               S+   + T+ +LD E   ++Y + + A             RVE+ V DVNDN P   
Sbjct: 1616 AVNSETGWVTTLKELDREK-MQRYTIAVLATDQGDRIQHATGTRVEVTVADVNDNPPRFT 1674

Query: 795  KDFQIIFNNYKDCFPVGPFGRVPAYDADVTD---KLQYRILSGNNANLILLN--ETTGSM 849
             +      +  D  P G    +   DAD  D   ++ Y I  G+      +   +    +
Sbjct: 1675 AEIYKGTVSEDDPPPSGVIAILSTTDADSEDINKQVNYFITGGDPLGQFAIEHIQNEWKV 1734

Query: 850  TLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884
             +   L+        + ++ +DG+   KA +++ V
Sbjct: 1735 FVKKPLDREEKDNYLLNITASDGIFTAKATVEVKV 1769



 Score =  299 bits (734), Expect = 7e-79
 Identities = 261/947 (27%), Positives = 425/947 (44%), Gaps = 70/947 (7%)

Query: 15   DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
            D ND++PVF  + Y A+V E +  GT +L + A D D G N EV + +     ++     
Sbjct: 1029 DVNDNAPVFLSKAYHANVSEASVVGTRILQVDAKDSDTGNNQEVFFQLVEEKGES----- 1083

Query: 75   AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134
                         D F ID  +G + T   LD E++ ++ + V+A D+  P    LSS  
Sbjct: 1084 ------------SDFFTIDRDTGTISTAQLLDYEEIRQHELRVRAVDRGVPA---LSSEV 1128

Query: 135  TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194
             + +++ D NDN P+F+++TY  ++ E         I +++A+DAD      + +    G
Sbjct: 1129 IVTIDVTDLNDNAPEFTQQTYNSTISE--LAPRGHFITQVQASDADSSDKDNLLFFFTSG 1186

Query: 195  NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNA 254
            N  + FSID  +G + +           Y L +   DG   S   +  +L+ +   N ++
Sbjct: 1187 NEDLNFSIDKHTGAILISNHRRVHMQPFYNLSVSVSDGVFRS---SAAVLVTVIGANFHS 1243

Query: 255  PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR 314
            P F  + F   + E+  I   +   +A DADEG+  ++ Y + + D+  +     +++  
Sbjct: 1244 PTFSQTEFVVELVEHSEIYTPVAEAKATDADEGIYGQIRYQIVN-DFAKD---KFSVN-E 1298

Query: 315  SGWVYTSGQLDRETQAK--YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE 372
            +G ++T   LDRE   +    + + A DGG   +                   F    Y+
Sbjct: 1299 NGEIFTLESLDRENNMEKVVPISLVARDGGG--KVGFCVVNVILTDINDNAPQFRAADYK 1356

Query: 373  VELAEDEPPGTPVVTLTATDADEDNR--LHYEITGG--NTRGRFSITSQNGRGLITVAQP 428
              +A D P GT VV ++A+D DE +   + Y I     N    F I   +  GLI   + 
Sbjct: 1357 STIASDVPRGTSVVRISASDLDEGSNADIEYSIEADVENVEENFEIHPTS--GLIVTKES 1414

Query: 429  LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV--FENAPYTASVFEDAPIGT 486
            L   +   Y   V A D+G     ++VQ+NI       P+  F  A Y  +V ED PIGT
Sbjct: 1415 LIGLENELYAFFVRAKDTGNPPQHSVVQVNIRIVAPETPIPKFNEAQYRYTVAEDLPIGT 1474

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
             + V+ A  +       + YSL    + E+ A  D+ FV++  +GA+   K LD ET   
Sbjct: 1475 EIDVIQAESAQ-----PLIYSLVKGSTPESNA--DEVFVVDRDSGALKLQKSLDHETTKW 1527

Query: 547  Y--LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
            Y  LL    +      ++    V I V DVNDN+PVF+   Y A ++E+   GT V QV 
Sbjct: 1528 YQFLLHSQTKHENFDIVASVI-VNIQVKDVNDNKPVFESDPYEAVVVENLPSGTQVIQVR 1586

Query: 605  ATDADVGLNGRIHYELDPKDREE---GSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
            A+D D G NG++ Y LD +   E     F ++  +G + T K LDRE +  + +  +A D
Sbjct: 1587 ASDQDSGTNGQVIYSLDARQSSEEISELFAVNSETGWVTTLKELDREKMQRYTIAVLATD 1646

Query: 662  GGTPPQSST-VIVHIKIEDINDSPPVFESDCLTFYISENSPIGT-TIGEIRAHDPD-EGP 718
             G   Q +T   V + + D+ND+PP F ++     +SE+ P  +  I  +   D D E  
Sbjct: 1647 QGDRIQHATGTRVEVTVADVNDNPPRFTAEIYKGTVSEDDPPPSGVIAILSTTDADSEDI 1706

Query: 719  NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDV 778
            N  V+Y I GGD    F++E  Q   K  +     LD E  +  Y L I A+        
Sbjct: 1707 NKQVNYFITGGDPLGQFAIEHIQNEWK--VFVKKPLDREE-KDNYLLNITASDGIFTAKA 1763

Query: 779  RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADVTDKLQ-YRILSGNN 836
             VE+ V D NDN+P  +   +   +  +  P G    +V A DAD+    Q +  L G  
Sbjct: 1764 TVEVKVLDANDNSPQCEK-ALYSESVPENSPAGRLILQVSASDADIRSNAQIFYELQGAG 1822

Query: 837  ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSI 896
            + L  ++  TG +     L+    +    ++   DG        +  + ++ E++  N  
Sbjct: 1823 SELFTIDSDTGELKTLQPLDREEQEEHRFKMRAVDGGGR---YCEADIHVVVEDVNDNLP 1879

Query: 897  TVRLNDMTAEQFLSPLLGFFIDGLAA--IIPCPKENIYIFSVQDDTD 941
                +  T   F +  +G ++  L A  +   P  NI I+S+ D  D
Sbjct: 1880 QFSADLYTVTVFENTEIGTYVAKLLANDVDVGPNSNI-IYSLLDSAD 1925



 Score =  297 bits (728), Expect = 4e-78
 Identities = 248/881 (28%), Positives = 396/881 (44%), Gaps = 68/881 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V+  N HSP F   ++   + E +   T V   KATD D G   ++ Y I        
Sbjct: 1234 VTVIGANFHSPTFSQTEFVVELVEHSEIYTPVAEAKATDADEGIYGQIRYQI-------- 1285

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVK--ATDQASPVSD 128
                            +D F ++  +G + T  SLDRE      V +   A D    V  
Sbjct: 1286 -----------VNDFAKDKFSVN-ENGEIFTLESLDRENNMEKVVPISLVARDGGGKVG- 1332

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
                   ++V + D NDN PQF    Y  ++  D  V     + +I A+D D G+N+ I 
Sbjct: 1333 ----FCVVNVILTDINDNAPQFRAADYKSTIASD--VPRGTSVVRISASDLDEGSNADIE 1386

Query: 189  YAIIGG--NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            Y+I     N +  F I   SG +   ++L   +   Y   +RA+D G+P + +  Q+ I 
Sbjct: 1387 YSIEADVENVEENFEIHPTSGLIVTKESLIGLENELYAFFVRAKDTGNPPQHSVVQVNIR 1446

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT-GNV 305
            I       P+F  + ++ +V+E++PIG  I  +QA  A       L Y++        N 
Sbjct: 1447 IVAPETPIPKFNEAQYRYTVAEDLPIGTEIDVIQAESAQP-----LIYSLVKGSTPESNA 1501

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLV-TATDGGDPPRSATATXXXXXXXXXXXXX 364
            D    +D  SG +     LD ET   YQ L+ + T   +    A+               
Sbjct: 1502 DEVFVVDRDSGALKLQKSLDHETTKWYQFLLHSQTKHENFDIVASVIVNIQVKDVNDNKP 1561

Query: 365  XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFS--ITSQNGR 420
             F    YE  + E+ P GT V+ + A+D D   + ++ Y +    +    S      +  
Sbjct: 1562 VFESDPYEAVVVENLPSGTQVIQVRASDQDSGTNGQVIYSLDARQSSEEISELFAVNSET 1621

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM---VQINITDANNYAPVFENAPYTAS 477
            G +T  + LD ++ +RY + V ATD G R   A    V++ + D N+  P F    Y  +
Sbjct: 1622 GWVTTLKELDREKMQRYTIAVLATDQGDRIQHATGTRVEVTVADVNDNPPRFTAEIYKGT 1681

Query: 478  VFEDAPIGTTVL-VVSATDSDV-GINAQITYSLSS--EISNEAVAHHDQQFVINPQTGAI 533
            V ED P  + V+ ++S TD+D   IN Q+ Y ++    +   A+ H   ++        +
Sbjct: 1682 VSEDDPPPSGVIAILSTTDADSEDINKQVNYFITGGDPLGQFAIEHIQNEW-------KV 1734

Query: 534  TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593
               K LDRE    YLL +TA DG     +    VE+ V+D NDN P  ++ LY+ ++ E+
Sbjct: 1735 FVKKPLDREEKDNYLLNITASDG---IFTAKATVEVKVLDANDNSPQCEKALYSESVPEN 1791

Query: 594  ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653
            +  G  + QV A+DAD+  N +I YEL     E   F ID  +G ++T + LDRE    H
Sbjct: 1792 SPAGRLILQVSASDADIRSNAQIFYELQGAGSE--LFTIDSDTGELKTLQPLDREEQEEH 1849

Query: 654  DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713
              K  A+DGG   +     +H+ +ED+ND+ P F +D  T  + EN+ IGT + ++ A+D
Sbjct: 1850 RFKMRAVDGGG--RYCEADIHVVVEDVNDNLPQFSADLYTVTVFENTEIGTYVAKLLAND 1907

Query: 714  PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP 773
             D GPN+ + YS+    D   FS++ + G    E    +D + +S  +   L      P 
Sbjct: 1908 VDVGPNSNIIYSLLDSADG-FFSIDEQTGVISLE--RPLDRELQSTYELRALASDQGLPR 1964

Query: 774  LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY--DADVTDKLQYRI 831
            L +  +V + V D+NDN PV +  +      +D        RV A   D +   ++ Y I
Sbjct: 1965 LSSVCQVVVSVLDINDNPPVFEHREYTATVSEDVSVGTQLLRVQAASRDTEANGEISYGI 2024

Query: 832  LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            +SGN   L  ++  TG + +   L+        + V  TDG
Sbjct: 2025 ISGNEHGLFSVDPRTGDIFVIQPLDYEASHEYYITVEATDG 2065



 Score =  274 bits (673), Expect = 2e-71
 Identities = 206/771 (26%), Positives = 356/771 (46%), Gaps = 52/771 (6%)

Query: 138 VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQ 197
           + +ID N++ PQFSEK Y V+V ED        + +I A+D D    + + + ++     
Sbjct: 198 IRVIDTNNHRPQFSEKFYEVNVAED--TPPGTEVLQISASDRD--EKNKLTFTLLSSTDP 253

Query: 198 M---QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNA 254
               +F +D  +G +   +TLD+E +  + L +  +D   P + N  ++++N+ D NDNA
Sbjct: 254 FSLRKFRLDPGTGTLYTAETLDHETMHHHILTVMVRDQDIPVKRNLVRVIVNVDDTNDNA 313

Query: 255 PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR 314
           P F  + F   V E+  +G ++++V A D D+G NAE+ Y++     +GN     +IDP+
Sbjct: 314 PWFVGAPFSGRVFESAAVGSAVLQVTARDKDKGRNAEVVYSLE----SGNFANTFSIDPK 369

Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374
            G +  + +LDR+++A+Y+L V A+D G PP S TA               F   ++  +
Sbjct: 370 LGTITVAKELDRDSKAQYELTVKASDNGVPPLSTTAPVRIAVTVSDNAAPRFTEREFSAD 429

Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434
           ++E   PG+ V  +TA+     + + Y+I  GN    F I   +  G++   +PLD++  
Sbjct: 430 VSESAHPGSFVALVTAS---SQSSVFYQIKAGNINNAFDINPNS--GVVVTQRPLDYETT 484

Query: 435 RRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV------ 488
            +Y L +  T+  G      + +++ D N+ AP+F    +   V E AP+ + V      
Sbjct: 485 AQYTLVIQGTNMAGLGTNTTLLVHLKDENDNAPIFIQKEFRGVVSESAPVNSVVLTRENT 544

Query: 489 -LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
            LVV A+D+D   NA + Y +      E  AH+   F I+  TGAI     LD E  + +
Sbjct: 545 PLVVRASDADGDQNAMLIYQIV-----EPFAHN--YFAIDSNTGAIRITTALDYEERNTF 597

Query: 548 LLTVTARDGGVPSLSDTT--DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
             TV   D G+P L   T  +V I V DVND  PVF Q+ Y A ++     G  V Q+ A
Sbjct: 598 HFTVQVHDLGIPRLFAETAANVTIEVTDVNDCPPVFSQKTYEATVITPTYKGVKVIQINA 657

Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
           TD+D G N ++   +   +  +  F +DP +G+I         S   ++LK    DG   
Sbjct: 658 TDSDSGPNAKLLLSISEGNIGD-KFKMDPTTGIISVQNVTQLRS--RYELKVRVSDGRF- 713

Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
             SS   V I +++  ++   F  +    ++ ENS    T+  I A       N  + Y+
Sbjct: 714 --SSVATVKINVKENKENKLKFTKESYKAFVQENSSEKKTLEVIAA--VGNQVNEPLFYN 769

Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND---VRVEI 782
           I   D    F +    G       T +  D E+ +  +E+V+         D   V + +
Sbjct: 770 ILNPD--KKFEISRTSG---VVSTTGIPFDREA-QDTFEIVVEVTREGQSEDGAHVLLTV 823

Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILL 842
           +V D NDN P+  +         D        +V A D D+    + + L   +     +
Sbjct: 824 MVEDANDNRPMFVNLPYHALVQMDAEEGHLIRQVTAVDRDMGQNAEIQYLLKEHQEFFQI 883

Query: 843 NETTGSMTLSPQLNTNV--PKLATMEVSVTDGVNEIKAMMQLSVRLITEEM 891
           +  +G ++L  +L           + V+  +G   + A +++ V ++ + M
Sbjct: 884 S-PSGEISLKKKLQKESLNTDFVIVVVAQDNGNPALSAEVEVPVTVVNKAM 933



 Score =  261 bits (640), Expect = 2e-67
 Identities = 268/961 (27%), Positives = 433/961 (45%), Gaps = 95/961 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +NV D ND++P F    +   V E A+ G+ VL + A D+D G+NAEV Y++E       
Sbjct: 304  VNVDDTNDNAPWFVGAPFSGRVFESAAVGSAVLQVTARDKDKGRNAEVVYSLE------- 356

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                             + F ID + G +     LDR+  A+Y + VKA+D   P    L
Sbjct: 357  ------------SGNFANTFSIDPKLGTITVAKELDRDSKAQYELTVKASDNGVP---PL 401

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S+TA + + +   ++  P+F+E+ ++  V E  S      +A + A+     + S++ Y 
Sbjct: 402  STTAPVRIAVTVSDNAAPRFTEREFSADVSE--SAHPGSFVALVTAS-----SQSSVFYQ 454

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I  GN    F I+  SG V   + LDYE    Y LVI+  +      +NTT LL++++D 
Sbjct: 455  IKAGNINNAFDINPNSGVVVTQRPLDYETTAQYTLVIQGTNMAGLG-TNTT-LLVHLKDE 512

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVR-------VQAYDADEGVNAELTYTMTDKDYTG 303
            NDNAP F    F+  VSE+ P+   ++        V+A DAD   NA L Y + +  +  
Sbjct: 513  NDNAPIFIQKEFRGVVSESAPVNSVVLTRENTPLVVRASDADGDQNAMLIYQIVE-PFAH 571

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA--TATXXXXXXXXXX 361
            N      ID  +G +  +  LD E +  +   V   D G P   A   A           
Sbjct: 572  NY---FAIDSNTGAIRITTALDYEERNTFHFTVQVHDLGIPRLFAETAANVTIEVTDVND 628

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNG 419
                F    YE  +      G  V+ + ATD+D   + +L   I+ GN   +F +     
Sbjct: 629  CPPVFSQKTYEATVITPTYKGVKVIQINATDSDSGPNAKLLLSISEGNIGDKFKMDPTT- 687

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479
             G+I+V      +   RY L V  +D G  S  A V+IN+ +       F    Y A V 
Sbjct: 688  -GIISVQNVTQLRS--RYELKVRVSD-GRFSSVATVKINVKENKENKLKFTKESYKAFVQ 743

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL- 538
            E++    T+ V++A  + V  N  + Y+         + + D++F I+  +G ++T  + 
Sbjct: 744  ENSSEKKTLEVIAAVGNQV--NEPLFYN---------ILNPDKKFEISRTSGVVSTTGIP 792

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
             DRE    + + V     G         + + V D NDN P+F    Y A +  DA  G 
Sbjct: 793  FDREAQDTFEIVVEVTREGQSEDGAHVLLTVMVEDANDNRPMFVNLPYHALVQMDAEEGH 852

Query: 599  SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT-HDLKA 657
             + QV A D D+G N  I Y L  K+ +E  F I P SG I   K L +ES+ T   +  
Sbjct: 853  LIRQVTAVDRDMGQNAEIQYLL--KEHQE-FFQISP-SGEISLKKKLQKESLNTDFVIVV 908

Query: 658  VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
            VA D G P  S+ V V + +  +N + P FE    T  I EN  + T +  ++A++  EG
Sbjct: 909  VAQDNGNPALSAEVEVPVTV--VNKAMPAFEKAFYTIEIPENIQLHTPVLHVQANN-SEG 965

Query: 718  PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--PPLW 775
            P  V  Y+I  GD    FS++   G     +  +  LD+E+    Y+L +RA        
Sbjct: 966  PRIV--YTISEGDPFKQFSIDFNTG----VIHVIQPLDFET-HPAYKLSVRATDSLTGAH 1018

Query: 776  NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADV--TDKLQYRIL 832
            +DV V+I++ DVNDNAPV    +    N  +   VG    +V A D+D     ++ ++++
Sbjct: 1019 SDVFVDIILEDVNDNAPVFLS-KAYHANVSEASVVGTRILQVDAKDSDTGNNQEVFFQLV 1077

Query: 833  --SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITE 889
               G +++   ++  TG+++ +  L+    +   + V   D GV  + + + +++  +T+
Sbjct: 1078 EEKGESSDFFTIDRDTGTISTAQLLDYEEIRQHELRVRAVDRGVPALSSEVIVTID-VTD 1136

Query: 890  EMLLNSITVRLNDMTAEQFLSPLL--GFFIDGLAA--IIPCPKENIYIFSVQDDTDVTGN 945
               LN         T    +S L   G FI  + A       K+N+  F    + D+  +
Sbjct: 1137 ---LNDNAPEFTQQTYNSTISELAPRGHFITQVQASDADSSDKDNLLFFFTSGNEDLNFS 1193

Query: 946  I 946
            I
Sbjct: 1194 I 1194



 Score =  260 bits (636), Expect = 5e-67
 Identities = 236/875 (26%), Positives = 385/875 (44%), Gaps = 59/875 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +++ D ND++P+F  +++   V E A   + VLT + T             + +  +D  
Sbjct: 507  VHLKDENDNAPIFIQKEFRGVVSESAPVNSVVLTRENTP------------LVVRASDAD 554

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
              ++A            + F ID  +GA+    +LD E+   +   V+  D   P   RL
Sbjct: 555  GDQNAMLIYQIVEPFAHNYFAIDSNTGAIRITTALDYEERNTFHFTVQVHDLGIP---RL 611

Query: 131  --SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV-IAKIKATDADVGANSAI 187
               + A + + + D ND  P FS+KTY  +V   I+ T   V + +I ATD+D G N+ +
Sbjct: 612  FAETAANVTIEVTDVNDCPPVFSQKTYEATV---ITPTYKGVKVIQINATDSDSGPNAKL 668

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGGSPSRSNTTQLLIN 246
              +I  GN   +F +D  +G +S+       Q+RS Y L +R  DG     S+   + IN
Sbjct: 669  LLSISEGNIGDKFKMDPTTGIISVQNVT---QLRSRYELKVRVSDGRF---SSVATVKIN 722

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            +++  +N  +F    ++  V EN     ++  + A      VN  L Y +       N D
Sbjct: 723  VKENKENKLKFTKESYKAFVQENSSEKKTLEVIAA--VGNQVNEPLFYNIL------NPD 774

Query: 307  LPITIDPRSGWVYTSG-QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
                I   SG V T+G   DRE Q  ++++V  T  G     A                 
Sbjct: 775  KKFEISRTSGVVSTTGIPFDREAQDTFEIVVEVTREGQSEDGAHVLLTVMVEDANDNRPM 834

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV 425
            F+   Y   +  D   G  +  +TA D D       +      +  F I+      L   
Sbjct: 835  FVNLPYHALVQMDAEEGHLIRQVTAVDRDMGQNAEIQYLLKEHQEFFQISPSGEISLKKK 894

Query: 426  AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
             Q      +  +V+ V A D+G  + +A V++ +T  N   P FE A YT  + E+  + 
Sbjct: 895  LQKESLNTD--FVIVVVAQDNGNPALSAEVEVPVTVVNKAMPAFEKAFYTIEIPENIQLH 952

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
            T VL V A +S+     +I Y++S            +QF I+  TG I   + LD ET  
Sbjct: 953  TPVLHVQANNSE---GPRIVYTISE-------GDPFKQFSIDFNTGVIHVIQPLDFETHP 1002

Query: 546  GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
             Y L+V A D    + SD   V+I + DVNDN PVF  + Y AN+ E ++VGT + QV A
Sbjct: 1003 AYKLSVRATDSLTGAHSDVF-VDIILEDVNDNAPVFLSKAYHANVSEASVVGTRILQVDA 1061

Query: 606  TDADVGLNGRIHYEL-DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
             D+D G N  + ++L + K      F ID  +G I T + LD E +  H+L+  A+D G 
Sbjct: 1062 KDSDTGNNQEVFFQLVEEKGESSDFFTIDRDTGTISTAQLLDYEEIRQHELRVRAVDRGV 1121

Query: 665  PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
            P  SS VIV I + D+ND+ P F        ISE +P G  I +++A D D      + +
Sbjct: 1122 PALSSEVIVTIDVTDLNDNAPEFTQQTYNSTISELAPRGHFITQVQASDADSSDKDNLLF 1181

Query: 725  SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILV 784
                G++  +FS++   G   A L++     +  P   Y L +  +     +   V + V
Sbjct: 1182 FFTSGNEDLNFSIDKHTG---AILISNHRRVHMQP--FYNLSVSVSDGVFRSSAAVLVTV 1236

Query: 785  TDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILL 842
               N ++P     + +    +      P     A DAD  +  +++Y+I++    +   +
Sbjct: 1237 IGANFHSPTFSQTEFVVELVEHSEIYTPVAEAKATDADEGIYGQIRYQIVNDFAKDKFSV 1296

Query: 843  NETTGSMTL-SPQLNTNVPKLATMEVSVTDGVNEI 876
            NE     TL S     N+ K+  + +   DG  ++
Sbjct: 1297 NENGEIFTLESLDRENNMEKVVPISLVARDGGGKV 1331



 Score =  237 bits (581), Expect = 2e-60
 Identities = 223/802 (27%), Positives = 352/802 (43%), Gaps = 79/802 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V+D N+H P F  + YE +V E    GT VL + A+D+D  KN ++ +T+ L + D  
Sbjct: 198 IRVIDTNNHRPQFSEKFYEVNVAEDTPPGTEVLQISASDRD-EKN-KLTFTL-LSSTDPF 254

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           +                  FR+D  +G L T  +LD E +  + + V   DQ  PV   L
Sbjct: 255 SLRK---------------FRLDPGTGTLYTAETLDHETMHHHILTVMVRDQDIPVKRNL 299

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
                + VN+ D NDN P F    ++  V E  +V     + ++ A D D G N+ + Y+
Sbjct: 300 ---VRVIVNVDDTNDNAPWFVGAPFSGRVFESAAV--GSAVLQVTARDKDKGRNAEVVYS 354

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
           +  GN    FSID   G +++ K LD +    Y L ++A D G P  S T  + I +   
Sbjct: 355 LESGNFANTFSIDPKLGTITVAKELDRDSKAQYELTVKASDNGVPPLSTTAPVRIAVTVS 414

Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
           ++ APRF    F   VSE+   G  +  V A        + + Y +      GN++    
Sbjct: 415 DNAAPRFTEREFSADVSESAHPGSFVALVTA-----SSQSSVFYQIK----AGNINNAFD 465

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
           I+P SG V T   LD ET A+Y L++  T+          T              F+  +
Sbjct: 466 INPNSGVVVTQRPLDYETTAQYTLVIQGTNMAG--LGTNTTLLVHLKDENDNAPIFIQKE 523

Query: 371 YEVELAEDEPPGTPVVT-------LTATDADEDNR--LHYEITGGNTRGRFSITSQNGRG 421
           +   ++E  P  + V+T       + A+DAD D    L Y+I        F+I S  G  
Sbjct: 524 FRGVVSESAPVNSVVLTRENTPLVVRASDADGDQNAMLIYQIVEPFAHNYFAIDSNTGAI 583

Query: 422 LITVAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNYAPVFENAPYTAS 477
            IT A  LD+++   +  TV   D G         A V I +TD N+  PVF    Y A+
Sbjct: 584 RITTA--LDYEERNTFHFTVQVHDLGIPRLFAETAANVTIEVTDVNDCPPVFSQKTYEAT 641

Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
           V      G  V+ ++ATDSD G NA++  S+S         +   +F ++P TG I+   
Sbjct: 642 VITPTYKGVKVIQINATDSDSGPNAKLLLSISE-------GNIGDKFKMDPTTGIISVQN 694

Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
           +   +  S Y L V   DG     S    V+I+V +  +N+  F ++ Y A + E++   
Sbjct: 695 V--TQLRSRYELKVRVSDG---RFSSVATVKINVKENKENKLKFTKESYKAFVQENSSEK 749

Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK-ALDRESVATHDLK 656
            ++  + A    V  N  + Y +   D++   F I   SGV+ T     DRE+  T ++ 
Sbjct: 750 KTLEVIAAVGNQV--NEPLFYNILNPDKK---FEISRTSGVVSTTGIPFDREAQDTFEIV 804

Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
                 G     + V++ + +ED ND+ P+F +      +  ++  G  I ++ A D D 
Sbjct: 805 VEVTREGQSEDGAHVLLTVMVEDANDNRPMFVNLPYHALVQMDAEEGHLIRQVTAVDRDM 864

Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPP 773
           G NA + Y +K  +    F +     S   E+     L  ES    + +V+ A    +P 
Sbjct: 865 GQNAEIQYLLK--EHQEFFQI-----SPSGEISLKKKLQKESLNTDFVIVVVAQDNGNPA 917

Query: 774 LWNDVRVEILVTDVNDNAPVMK 795
           L     VE+ VT VN   P  +
Sbjct: 918 L--SAEVEVPVTVVNKAMPAFE 937



 Score =  196 bits (477), Expect = 1e-47
 Identities = 160/571 (28%), Positives = 259/571 (45%), Gaps = 40/571 (7%)

Query: 233 GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292
           G+ +  +   +LI + D N++ P+F    ++ +V+E+ P G  ++++ A D DE    +L
Sbjct: 186 GTKALHHLLLVLIRVIDTNNHRPQFSEKFYEVNVAEDTPPGTEVLQISASDRDE--KNKL 243

Query: 293 TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352
           T+T+       ++     +DP +G +YT+  LD ET   + L V   D   P +      
Sbjct: 244 TFTLLSSTDPFSL-RKFRLDPGTGTLYTAETLDHETMHHHILTVMVRDQDIPVKRNLVRV 302

Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRG 410
                        F+   +   + E    G+ V+ +TA D D+       Y +  GN   
Sbjct: 303 IVNVDDTNDNAPWFVGAPFSGRVFESAAVGSAVLQVTARDKDKGRNAEVVYSLESGNFAN 362

Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPV 468
            FSI  +   G ITVA+ LD   + +Y LTV A+D+G    S TA V+I +T ++N AP 
Sbjct: 363 TFSIDPK--LGTITVAKELDRDSKAQYELTVKASDNGVPPLSTTAPVRIAVTVSDNAAPR 420

Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528
           F    ++A V E A  G+ V +V+A+       + + Y + +   N A       F INP
Sbjct: 421 FTEREFSADVSESAHPGSFVALVTASS-----QSSVFYQIKAGNINNA-------FDINP 468

Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588
            +G + T + LD ET + Y L +   +  +  L   T + + + D NDN P+F Q+ +  
Sbjct: 469 NSGVVVTQRPLDYETTAQYTLVIQGTN--MAGLGTNTTLLVHLKDENDNAPIFIQKEFRG 526

Query: 589 NIMEDALVGTSVSQ-------VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641
            + E A V + V         V A+DAD   N  + Y++  +      F ID  +G IR 
Sbjct: 527 VVSESAPVNSVVLTRENTPLVVRASDADGDQNAMLIYQI-VEPFAHNYFAIDSNTGAIRI 585

Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE--DINDSPPVFESDCLTFYISEN 699
             ALD E   T        D G P   +    ++ IE  D+ND PPVF        +   
Sbjct: 586 TTALDYEERNTFHFTVQVHDLGIPRLFAETAANVTIEVTDVNDCPPVFSQKTYEATVITP 645

Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759
           +  G  + +I A D D GPNA +  SI  G+  + F ++   G    + VT +       
Sbjct: 646 TYKGVKVIQINATDSDSGPNAKLLLSISEGNIGDKFKMDPTTGIISVQNVTQL------- 698

Query: 760 RKKYELVIRAASPPLWNDVRVEILVTDVNDN 790
           R +YEL +R +     +   V+I V +  +N
Sbjct: 699 RSRYELKVRVSDGRFSSVATVKINVKENKEN 729



 Score =  173 bits (420), Expect = 8e-41
 Identities = 128/413 (30%), Positives = 203/413 (49%), Gaps = 27/413 (6%)

Query: 454 MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513
           +V I + D NN+ P F    Y  +V ED P GT VL +SA+D D     ++T++L S   
Sbjct: 195 LVLIRVIDTNNHRPQFSEKFYEVNVAEDTPPGTEVLQISASDRDE--KNKLTFTLLSSTD 252

Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
             ++    ++F ++P TG + T + LD ETM  ++LTV  RD  +P   +   V ++V D
Sbjct: 253 PFSL----RKFRLDPGTGTLYTAETLDHETMHHHILTVMVRDQDIPVKRNLVRVIVNVDD 308

Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633
            NDN P F    ++  + E A VG++V QV A D D G N  + Y L+       +F ID
Sbjct: 309 TNDNAPWFVGAPFSGRVFESAAVGSAVLQVTARDKDKGRNAEVVYSLE-SGNFANTFSID 367

Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693
           P  G I   K LDR+S A ++L   A D G PP S+T  V I +   +++ P F     +
Sbjct: 368 PKLGTITVAKELDRDSKAQYELTVKASDNGVPPLSTTAPVRIAVTVSDNAAPRFTEREFS 427

Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753
             +SE++  G+ +  + A        + V Y IK G+ +N+F +    G     +VT   
Sbjct: 428 ADVSESAHPGSFVALVTA-----SSQSSVFYQIKAGNINNAFDINPNSG----VVVTQRP 478

Query: 754 LDYESPRKKYELVIRAAS-PPLWNDVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFPV 810
           LDYE+   +Y LVI+  +   L  +  + + + D NDNAP  + K+F+ + +       V
Sbjct: 479 LDYET-TAQYTLVIQGTNMAGLGTNTTLLVHLKDENDNAPIFIQKEFRGVVSESAPVNSV 537

Query: 811 ------GPF-GRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
                  P   R    D D    L Y+I+     N   ++  TG++ ++  L+
Sbjct: 538 VLTRENTPLVVRASDADGDQNAMLIYQIVEPFAHNYFAIDSNTGAIRITTALD 590



 Score =  125 bits (301), Expect = 2e-26
 Identities = 89/320 (27%), Positives = 156/320 (48%), Gaps = 15/320 (4%)

Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV--GLNG 614
           G  +L     V I V+D N++ P F ++ Y  N+ ED   GT V Q+ A+D D    L  
Sbjct: 186 GTKALHHLLLVLIRVIDTNNHRPQFSEKFYEVNVAEDTPPGTEVLQISASDRDEKNKLTF 245

Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674
            +    DP    +  F +DP +G + T + LD E++  H L  +  D   P + + V V 
Sbjct: 246 TLLSSTDPFSLRK--FRLDPGTGTLYTAETLDHETMHHHILTVMVRDQDIPVKRNLVRVI 303

Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734
           + ++D ND+ P F     +  + E++ +G+ + ++ A D D+G NA V YS++ G+ +N+
Sbjct: 304 VNVDDTNDNAPWFVGAPFSGRVFESAAVGSAVLQVTARDKDKGRNAEVVYSLESGNFANT 363

Query: 735 FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNA 791
           FS++ + G+    +    +LD +S + +YEL ++A+    PPL     V I VT  ++ A
Sbjct: 364 FSIDPKLGT----ITVAKELDRDS-KAQYELTVKASDNGVPPLSTTAPVRIAVTVSDNAA 418

Query: 792 PVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTL 851
           P   + +   +  +   P G F  V    A     + Y+I +GN  N   +N  +G +  
Sbjct: 419 PRFTEREFSADVSESAHP-GSF--VALVTASSQSSVFYQIKAGNINNAFDINPNSGVVVT 475

Query: 852 SPQLNTNVPKLATMEVSVTD 871
              L+       T+ +  T+
Sbjct: 476 QRPLDYETTAQYTLVIQGTN 495



 Score =  117 bits (282), Expect = 4e-24
 Identities = 81/247 (32%), Positives = 119/247 (48%), Gaps = 36/247 (14%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            ++VLD ND+ PVFE ++Y A+V E  S GT +L ++A  +D   N E+ Y I        
Sbjct: 1973 VSVLDINDNPPVFEHREYTATVSEDVSVGTQLLRVQAASRDTEANGEISYGI-------- 2024

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                              +F +D R+G +     LD E    Y + V+ATD  SP    L
Sbjct: 2025 -----------ISGNEHGLFSVDPRTGDIFVIQPLDYEASHEYYITVEATDGGSPP---L 2070

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S  AT+++N+ D NDN P FS+  YT  V ED  +     +  + A D D  ++S +RY+
Sbjct: 2071 SDMATVNINLTDVNDNRPVFSQDVYTAVVSEDAEL--GKTVITVNAEDLDGPSHSHVRYS 2128

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I+ GN    F+IDS  G++ +   LD E  R  R          P  ++  QL +  RD 
Sbjct: 2129 IVDGNQGSPFTIDSARGELKVAHQLDRE--RENR----------PKGTSVLQLTVTDRDA 2176

Query: 251  NDNAPRF 257
            + N P F
Sbjct: 2177 SHNGPPF 2183



 Score = 79.0 bits (186), Expect = 2e-12
 Identities = 54/178 (30%), Positives = 89/178 (50%), Gaps = 17/178 (9%)

Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI-------MEDALVGTSVSQV 603
           +T  D GVP+ S +  V + V+D NDN P+F +++Y   +        E A+    V +V
Sbjct: 1   ITVTDHGVPAKSTSVRVIVQVLDENDNRPLFLEKIYKIKLPEREKPEKERAIKRDPVYRV 60

Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV-AIDG 662
            A+D D G N  I Y ++  D E G F I+P +G++ + K     S   +D+  + A+D 
Sbjct: 61  IASDRDDGPNAEISYSIEEGD-ENGKFFIEPKTGLVSSKKF---SSAGEYDILTIKAVDN 116

Query: 663 GTPPQSSTVIVHI----KIEDINDSPPV-FESDCLTFYISENSPIGTTIGEIRAHDPD 715
           G P +SS+  +HI    K +   D+ P+ FE     F + E+ P+   +G +     D
Sbjct: 117 GRPQKSSSCRLHIEWIPKPKLPPDAAPLQFEESPFVFSVMESDPVAHMVGVVATEASD 174



 Score = 64.1 bits (149), Expect = 5e-08
 Identities = 56/189 (29%), Positives = 93/189 (49%), Gaps = 19/189 (10%)

Query: 117 VKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE------DISVTDNPV 170
           +  TD   P     S++  + V ++D+NDN P F EK Y + + E      + ++  +PV
Sbjct: 1   ITVTDHGVPAK---STSVRVIVQVLDENDNRPLFLEKIYKIKLPEREKPEKERAIKRDPV 57

Query: 171 IAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR-LVIRA 229
             ++ A+D D G N+ I Y+I  G+   +F I+  +G   LV +  +     Y  L I+A
Sbjct: 58  Y-RVIASDRDDGPNAEISYSIEEGDENGKFFIEPKTG---LVSSKKFSSAGEYDILTIKA 113

Query: 230 QDGGSPSRSNTTQLLI----NIRDVNDNAP-RFYTSLFQESVSENVPIGYSIVRVQAYDA 284
            D G P +S++ +L I      +   D AP +F  S F  SV E+ P+ + +  V    +
Sbjct: 114 VDNGRPQKSSSCRLHIEWIPKPKLPPDAAPLQFEESPFVFSVMESDPVAHMVGVVATEAS 173

Query: 285 DEGVNAELT 293
           D  V  E+T
Sbjct: 174 DVPVWFEIT 182



 Score = 56.4 bits (130), Expect = 1e-05
 Identities = 56/219 (25%), Positives = 96/219 (43%), Gaps = 9/219 (4%)

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
           + +  GT      ++V I++ D N+  P F        ++E++P GT + +I A D DE 
Sbjct: 181 ITVRWGTKALHHLLLVLIRVIDTNNHRPQFSEKFYEVNVAEDTPPGTEVLQISASDRDE- 239

Query: 718 PNAVVHYSIKGGDDSNSFSL-ETRQGSDKAELVTMVDLDYESPRKK-YELVIRAASPPL- 774
            N +    +   D    FSL + R       L T   LD+E+       +++R    P+ 
Sbjct: 240 KNKLTFTLLSSTD---PFSLRKFRLDPGTGTLYTAETLDHETMHHHILTVMVRDQDIPVK 296

Query: 775 WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRIL 832
            N VRV + V D NDNAP           ++         +V A D D     ++ Y + 
Sbjct: 297 RNLVRVIVNVDDTNDNAPWFVGAPFSGRVFESAAVGSAVLQVTARDKDKGRNAEVVYSLE 356

Query: 833 SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
           SGN AN   ++   G++T++ +L+ +      + V  +D
Sbjct: 357 SGNFANTFSIDPKLGTITVAKELDRDSKAQYELTVKASD 395



 Score = 52.4 bits (120), Expect = 2e-04
 Identities = 48/190 (25%), Positives = 85/190 (44%), Gaps = 20/190 (10%)

Query: 227 IRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLF-------QESVSENVPIGYSIVRV 279
           I   D G P++S + ++++ + D NDN P F   ++       ++   E       + RV
Sbjct: 1   ITVTDHGVPAKSTSVRVIVQVLDENDNRPLFLEKIYKIKLPEREKPEKERAIKRDPVYRV 60

Query: 280 QAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL-VTA 338
            A D D+G NAE++Y++ + D  G       I+P++G V +       +  +Y +L + A
Sbjct: 61  IASDRDDGPNAEISYSIEEGDENGK----FFIEPKTGLVSSK---KFSSAGEYDILTIKA 113

Query: 339 TDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE----VELAEDEPPGTPVVTLTATDAD 394
            D G P +S++                  P Q+E    V    +  P   +V + AT+A 
Sbjct: 114 VDNGRPQKSSSCRLHIEWIPKPKLPPDAAPLQFEESPFVFSVMESDPVAHMVGVVATEA- 172

Query: 395 EDNRLHYEIT 404
            D  + +EIT
Sbjct: 173 SDVPVWFEIT 182



 Score = 51.6 bits (118), Expect = 3e-04
 Identities = 49/187 (26%), Positives = 81/187 (43%), Gaps = 22/187 (11%)

Query: 336 VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT-------PVVTL 388
           +T TD G P +S +                F+   Y+++L E E P         PV  +
Sbjct: 1   ITVTDHGVPAKSTSVRVIVQVLDENDNRPLFLEKIYKIKLPEREKPEKERAIKRDPVYRV 60

Query: 389 TATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY-VLTVSATD 445
            A+D D+  +  + Y I  G+  G+F I  + G     +     F     Y +LT+ A D
Sbjct: 61  IASDRDDGPNAEISYSIEEGDENGKFFIEPKTG-----LVSSKKFSSAGEYDILTIKAVD 115

Query: 446 SGGRSDTAMVQINITDAN------NYAPV-FENAPYTASVFEDAPIGTTVLVVSATDSDV 498
           +G    ++  +++I          + AP+ FE +P+  SV E  P+   V VV+   SDV
Sbjct: 116 NGRPQKSSSCRLHIEWIPKPKLPPDAAPLQFEESPFVFSVMESDPVAHMVGVVATEASDV 175

Query: 499 GINAQIT 505
            +  +IT
Sbjct: 176 PVWFEIT 182



 Score = 47.2 bits (107), Expect = 0.007
 Identities = 27/89 (30%), Positives = 45/89 (50%), Gaps = 7/89 (7%)

Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT-------IGEIRAHD 713
           D G P +S++V V +++ D ND+ P+F        + E              +  + A D
Sbjct: 5   DHGVPAKSTSVRVIVQVLDENDNRPLFLEKIYKIKLPEREKPEKERAIKRDPVYRVIASD 64

Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
            D+GPNA + YSI+ GD++  F +E + G
Sbjct: 65  RDDGPNAEISYSIEEGDENGKFFIEPKTG 93



 Score = 43.2 bits (97), Expect = 0.11
 Identities = 48/184 (26%), Positives = 78/184 (42%), Gaps = 23/184 (12%)

Query: 441 VSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASV-------FEDAPIGTTVLVV 491
           ++ TD G   +S +  V + + D N+  P+F    Y   +        E A     V  V
Sbjct: 1   ITVTDHGVPAKSTSVRVIVQVLDENDNRPLFLEKIYKIKLPEREKPEKERAIKRDPVYRV 60

Query: 492 SATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTV 551
            A+D D G NA+I+YS+     N        +F I P+TG +++ K          +LT+
Sbjct: 61  IASDRDDGPNAEISYSIEEGDEN-------GKFFIEPKTGLVSSKKFSSAGEYD--ILTI 111

Query: 552 TARDGGVPSLSDTTDVEISVVD----VNDNEPV-FKQQLYTANIMEDALVGTSVSQVGAT 606
            A D G P  S +  + I  +       D  P+ F++  +  ++ME   V   V  V   
Sbjct: 112 KAVDNGRPQKSSSCRLHIEWIPKPKLPPDAAPLQFEESPFVFSVMESDPVAHMVGVVATE 171

Query: 607 DADV 610
            +DV
Sbjct: 172 ASDV 175


>UniRef50_UPI0000E46DFB Cluster: PREDICTED: hypothetical protein; n=1;
            Strongylocentrotus purpuratus|Rep: PREDICTED:
            hypothetical protein - Strongylocentrotus purpuratus
          Length = 3342

 Score =  398 bits (979), Expect = e-108
 Identities = 290/880 (32%), Positives = 425/880 (48%), Gaps = 68/880 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            IN+LD ND++P F+      +++E       + T+ ATD D G N  + YTI        
Sbjct: 1434 INILDQNDNTPDFDQDLIYLTLQENVGINHVLWTVSATDADSGANGLIRYTI-------- 1485

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                            QD F +D  +G L T  ++D E    + ++++A DQA  VS R 
Sbjct: 1486 -------------LTEQDFFAVDEYTGTLRTIQNVDHEINHVFLLVIQAQDQAINVSARR 1532

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            ++T+T+ V I D NDN P F  ++ T  V ED  V  N  +  I ATD D G N  + Y 
Sbjct: 1533 AATSTVEVRIYDSNDNNPVFVSRSST-DVMEDEPVGFN--VIHIIATDEDSGENGRVGYT 1589

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I  GN   +FS+D+++G +++  +LD+E  R Y LVI A D G+  R  T  L I + DV
Sbjct: 1590 ITSGNEDGKFSLDAVTGLLTIAHSLDHEHKRDYELVILATDHGTVQRMATQTLTIRVIDV 1649

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            ND  PRF  S++  +VSE+   G  +  V A D D GVN  +TY + ++   G       
Sbjct: 1650 NDQPPRFEQSIYVMNVSESQAPGTYVGMVVAIDGDSGVNGRITYELPEEIARG----MFR 1705

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            I+  +G + T   LDRE +  Y + V A DG  P R   AT              F P  
Sbjct: 1706 INATTGEIRTKAILDREQRDSYVVTVYAMDGAFPARYDMATVLVYVMDVNDNNPTFAPPT 1765

Query: 371  YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
            +++ L E++ PG  +    ATDADE  +  L Y ITGG+ +  FSI    G  + TV   
Sbjct: 1766 FDITLPENQSPGV-IHNAIATDADEGPNGDLIYSITGGDPKNAFSINQSTG-AIFTVG-A 1822

Query: 429  LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
            LD + E  Y LT++ATD G   RS T  +++ +TD N+  PVF +  Y  S+ E   I  
Sbjct: 1823 LDREDEATYTLTITATDQGTSPRSGTTTIRVTVTDLNDNDPVFGSMSYYKSIPESTAINA 1882

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
            T+L V ATD D G+N  + Y+L     N  +      F I+P+ G ITT    D E  + 
Sbjct: 1883 TILTVVATDDDEGLNGDVYYTL----DNTTIG----LFSIDPEHGEITTTGKFDYEKETR 1934

Query: 547  YLLTVTARDGGV-PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
            Y   VTA D GV    S+   V I + DVNDN PVFK     AN+ +DA   T V+ V A
Sbjct: 1935 YTFQVTATDSGVFGPRSERVQVIIDISDVNDNAPVFKTIPIRANVTQDASSNTFVANVEA 1994

Query: 606  TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
             D D G+NG ++Y      ++  SF ID  +GVI T K+L+  ++  H L+ +A D G+P
Sbjct: 1995 DDKDSGVNGEVNYRF---TQQSSSFAIDTVTGVI-TTKSLNPGTLFYH-LEVMAFDLGSP 2049

Query: 666  PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
              SS  IV + +         F         SE +  G  +  + A  PD   +  + YS
Sbjct: 2050 SLSSNGIVEVWVGTSGSGGLQFGQQTYLVQPSEAADNGDVVLSLSAFLPDGSSSNDIVYS 2109

Query: 726  IKGGDDSNSFSLETRQGSDKAELVT-MVDLDYESPRKKYELVIRAA-----SPPLWNDVR 779
            +  G+++ +F ++ + G     +V     LDYE+ +    LV  A      S P++    
Sbjct: 2110 LVSGNENGAFGIQVQAGGSAILVVADTTKLDYET-QPNIRLVAEAMRTPENSSPMYGYAT 2168

Query: 780  VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-----FGRVPAYDAD--VTDKLQYRIL 832
            V++ +TD NDNAP     Q + + Y+      P       +V A DAD      + Y + 
Sbjct: 2169 VQVELTDANDNAP-----QFVQDRYQSRVWEVPNSDIYVTQVSATDADEGTNGAIYYEVT 2223

Query: 833  SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            SGN  N   ++  TG +T +  L+  +     + V   DG
Sbjct: 2224 SGNTDNAFAIDHVTGIVTTAKSLDYEIEDSYVLTVVARDG 2263



 Score =  343 bits (844), Expect = 3e-92
 Identities = 284/896 (31%), Positives = 418/896 (46%), Gaps = 68/896 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V+D ND++P F    ++ ++ E  S G  +    ATD D G N ++ Y+I   T    
Sbjct: 1749 VYVMDVNDNNPTFAPPTFDITLPENQSPGV-IHNAIATDADEGPNGDLIYSI---TGG-- 1802

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +P++A              F I+  +GA+ T  +LDRE  A YT+ + ATDQ +  S R 
Sbjct: 1803 DPKNA--------------FSINQSTGAIFTVGALDREDEATYTLTITATDQGT--SPR- 1845

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S T TI V + D NDN P F   +Y  S+ E  ++  N  I  + ATD D G N  + Y 
Sbjct: 1846 SGTTTIRVTVTDLNDNDPVFGSMSYYKSIPESTAI--NATILTVVATDDDEGLNGDVYYT 1903

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS-PSRSNTTQLLINIRD 249
            +    T   FSID   G+++     DYE+   Y   + A D G    RS   Q++I+I D
Sbjct: 1904 L-DNTTIGLFSIDPEHGEITTTGKFDYEKETRYTFQVTATDSGVFGPRSERVQVIIDISD 1962

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            VNDNAP F T   + +V+++      +  V+A D D GVN E+ Y  T +  +       
Sbjct: 1963 VNDNAPVFKTIPIRANVTQDASSNTFVANVEADDKDSGVNGEVNYRFTQQSSS------F 2016

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             ID  +G V T+  L+  T   Y L V A D G P  S+                 F   
Sbjct: 2017 AIDTVTG-VITTKSLNPGTLF-YHLEVMAFDLGSPSLSSNGIVEVWVGTSGSGGLQFGQQ 2074

Query: 370  QYEVELAEDEPPGTPVVTLTA--TDADEDNRLHYEITGGNTRGRFSITSQ-NGRGLITVA 426
             Y V+ +E    G  V++L+A   D    N + Y +  GN  G F I  Q  G  ++ VA
Sbjct: 2075 TYLVQPSEAADNGDVVLSLSAFLPDGSSSNDIVYSLVSGNENGAFGIQVQAGGSAILVVA 2134

Query: 427  QP--LDFKQERRYVLTVSATDSGGRSDT----AMVQINITDANNYAPVFENAPYTASVFE 480
                LD++ +    L   A  +   S      A VQ+ +TDAN+ AP F    Y + V+E
Sbjct: 2135 DTTKLDYETQPNIRLVAEAMRTPENSSPMYGYATVQVELTDANDNAPQFVQDRYQSRVWE 2194

Query: 481  DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
                   V  VSATD+D G N  I Y ++S        + D  F I+  TG +TT K LD
Sbjct: 2195 VPNSDIYVTQVSATDADEGTNGAIYYEVTS-------GNTDNAFAIDHVTGIVTTAKSLD 2247

Query: 541  RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
             E    Y+LTV ARDGG P L+ T  + I +VDVNDN+PVF Q +   ++ ED  VG SV
Sbjct: 2248 YEIEDSYVLTVVARDGGSPQLTGTATMRIGIVDVNDNQPVFVQ-MDPVSVSEDLGVGLSV 2306

Query: 601  SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
            + V ATD+D   N  I Y         G F ID  SG+I   ++LDRE+   + L+  A 
Sbjct: 2307 TTVTATDSDT--NPNIQYSFTSTGNPGGYFAIDQYSGIITLARSLDRETQDGYTLELEAT 2364

Query: 661  DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
            D      ++T+ + + + D ND+ PVF  +     + E +     +  + A D D G NA
Sbjct: 2365 D---TEYTTTMTLEVIVTDENDNAPVFRQESYQVTLPELTQPNVAVVAVNASDKDIGLNA 2421

Query: 721  VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRV 780
             + YS    D   SF ++   G      V   + D E+  + Y     + +P L   V V
Sbjct: 2422 ELTYSFV--DSHPSFYIDPITGVIFTNQVIEFN-DVETTIQLYVTATDSGAPALSEFVTV 2478

Query: 781  EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVT---DKLQYRILSGNN 836
             I +TDVN+ +PV  +  I   +  +   +G     V A D D++    K+ Y I SGN+
Sbjct: 2479 RIEITDVNNQSPVFVE-DIYSASVSENVSLGHHVITVVAEDMDLSPENSKINYFIESGND 2537

Query: 837  ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG---VNEIKAMMQLSVRLITE 889
                 ++   GS+T+  +L+       T+ +   D    VN   A + + V  I +
Sbjct: 2538 QGKFKIDANDGSITVLERLDREATDTYTLIIGAVDNGEPVNNATAEVVIEVEDIND 2593



 Score =  334 bits (822), Expect = 2e-89
 Identities = 263/879 (29%), Positives = 412/879 (46%), Gaps = 66/879 (7%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            +   I V+D ND+ P F  Q    S+ E    G+++    A D D G N  V Y +    
Sbjct: 911  VQVNITVIDVNDNVPQFMAQTARTSIPESTGIGSSIYVATAMDLDSGDNGLVRYRL---- 966

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
              T NP +               FRI   +G ++    +       + V ++A D   P 
Sbjct: 967  --TSNPGNT--------------FRIVEATGEIILNKEVSYNDQLSFEVDIQAYDAGEP- 1009

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
               L  + T+ V I+D NDN P F+   Y VS+ E++ ++  PV+ +++ATD D GAN+ 
Sbjct: 1010 --SLEGSLTLTVIILDVNDNGPVFTMGFYPVSILENLPIS-TPVV-QVEATDNDRGANAL 1065

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            I Y +   N    F++    G +   + LD E   ++ L I A D GSP ++++  + + 
Sbjct: 1066 ITYTLTPNNDSPYFAVFPREGWLYTRQVLDRELKSTFTLTIMASDSGSPPQNSSATVQVT 1125

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            + D NDNAP F    +   ++EN+P G  + RV+A D D G N ++TYT++    +G+  
Sbjct: 1126 VVDANDNAPHFTKKSYHFHINENLPAGTEVDRVEAVDPDLGPNGQVTYTLSP---SGD-- 1180

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
               TID   G + T+  LDRE    Y+L++ A DGG+P  S++AT              F
Sbjct: 1181 --FTID-EEGVIRTTHPLDREAAYSYRLIIRAVDGGNPALSSSATVYINVNDLNDNAPVF 1237

Query: 367  MPGQ-YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV 425
               + Y+  + E++P G  V  + ATD D     +   +  ++  +F I S    G+I+ 
Sbjct: 1238 SQDRTYQASVREEQPAGEFVAWIIATDTDSGVLGNISYSLIDSSPKFIIDSS---GVIST 1294

Query: 426  AQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
            A  +D + E  Y LTV A D G      TA V++ I D N+  P+   + Y  +  E+  
Sbjct: 1295 AAAIDREDESYYTLTVLAQDGGNPPMQATASVRVRILDLNDNVPIAAMSAYIFTADENIQ 1354

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
              T V VVSA+D DVG N +I Y ++         +    + +N  +G +   +++D E 
Sbjct: 1355 PPTVVGVVSASDMDVGDNGKIYYYITE-------GNDFDVWDVNHSSGEVYNVRVVDYEM 1407

Query: 544  MSGYLLTVTARDGGVPSLSDTT-DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
             + Y LT+ A+D  VP    T+  V I+++D NDN P F Q L    + E+  +   +  
Sbjct: 1408 AAHYTLTIIAQDNNVPQTHSTSISVTINILDQNDNTPDFDQDLIYLTLQENVGINHVLWT 1467

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
            V ATDAD G NG I Y +     E+  F +D  +G +RT + +D E      L   A D 
Sbjct: 1468 VSATDADSGANGLIRYTI---LTEQDFFAVDEYTGTLRTIQNVDHEINHVFLLVIQAQDQ 1524

Query: 663  G---TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
                +  +++T  V ++I D ND+ PVF S   T  + E+ P+G  +  I A D D G N
Sbjct: 1525 AINVSARRAATSTVEVRIYDSNDNNPVFVSRSST-DVMEDEPVGFNVIHIIATDEDSGEN 1583

Query: 720  AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRAASPPLWNDV 778
              V Y+I  G++   FSL+   G     L+T+   LD+E  ++ YELVI A        +
Sbjct: 1584 GRVGYTITSGNEDGKFSLDAVTG-----LLTIAHSLDHEH-KRDYELVILATDHGTVQRM 1637

Query: 779  RVEIL---VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILS 833
              + L   V DVND  P  +    + N  +   P    G V A D D  V  ++ Y +  
Sbjct: 1638 ATQTLTIRVIDVNDQPPRFEQSIYVMNVSESQAPGTYVGMVVAIDGDSGVNGRITYELPE 1697

Query: 834  GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
                 +  +N TTG +     L+        + V   DG
Sbjct: 1698 EIARGMFRINATTGEIRTKAILDREQRDSYVVTVYAMDG 1736



 Score =  333 bits (819), Expect = 3e-89
 Identities = 270/895 (30%), Positives = 411/895 (45%), Gaps = 65/895 (7%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ V D ND+ PVF    Y  S+ E  +   T+LT+ ATD D G N +V YT++  T   
Sbjct: 1852 RVTVTDLNDNDPVFGSMSYYKSIPESTAINATILTVVATDDDEGLNGDVYYTLDNTTI-- 1909

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                               +F ID   G + T    D EK  RYT  V ATD  S V   
Sbjct: 1910 ------------------GLFSIDPEHGEITTTGKFDYEKETRYTFQVTATD--SGVFGP 1949

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             S    + ++I D NDN P F       +V +D S   N  +A ++A D D G N  + Y
Sbjct: 1950 RSERVQVIIDISDVNDNAPVFKTIPIRANVTQDAS--SNTFVANVEADDKDSGVNGEVNY 2007

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
                      F+ID+++G V   K+L+      Y L + A D GSPS S+   + + +  
Sbjct: 2008 RFT--QQSSSFAIDTVTG-VITTKSLN-PGTLFYHLEVMAFDLGSPSLSSNGIVEVWVGT 2063

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
                  +F    +    SE    G  ++ + A+  D   + ++ Y++   +  G   + +
Sbjct: 2064 SGSGGLQFGQQTYLVQPSEAADNGDVVLSLSAFLPDGSSSNDIVYSLVSGNENGAFGIQV 2123

Query: 310  TIDPRSGWVYT-SGQLDRETQAKYQLLVTA--TDGGDPPRSATATXXXXXXXXXXXXXXF 366
                 +  V   + +LD ETQ   +L+  A  T     P    AT              F
Sbjct: 2124 QAGGSAILVVADTTKLDYETQPNIRLVAEAMRTPENSSPMYGYATVQVELTDANDNAPQF 2183

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLIT 424
            +  +Y+  + E       V  ++ATDADE  +  ++YE+T GNT   F+I   +  G++T
Sbjct: 2184 VQDRYQSRVWEVPNSDIYVTQVSATDADEGTNGAIYYEVTSGNTDNAFAI--DHVTGIVT 2241

Query: 425  VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
             A+ LD++ E  YVLTV A D G    + TA ++I I D N+  PVF       SV ED 
Sbjct: 2242 TAKSLDYEIEDSYVLTVVARDGGSPQLTGTATMRIGIVDVNDNQPVFVQMD-PVSVSEDL 2300

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
             +G +V  V+ATDSD   N  I YS +S        +    F I+  +G IT  + LDRE
Sbjct: 2301 GVGLSVTTVTATDSDT--NPNIQYSFTS------TGNPGGYFAIDQYSGIITLARSLDRE 2352

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
            T  GY L + A D      + T  +E+ V D NDN PVF+Q+ Y   + E      +V  
Sbjct: 2353 TQDGYTLELEATD---TEYTTTMTLEVIVTDENDNAPVFRQESYQVTLPELTQPNVAVVA 2409

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV-ATHDLKAVAID 661
            V A+D D+GLN  + Y          SF IDP +GVI TN+ ++   V  T  L   A D
Sbjct: 2410 VNASDKDIGLNAELTYSFVD---SHPSFYIDPITGVIFTNQVIEFNDVETTIQLYVTATD 2466

Query: 662  GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP-NA 720
             G P  S  V V I+I D+N+  PVF  D  +  +SEN  +G  +  + A D D  P N+
Sbjct: 2467 SGAPALSEFVTVRIEITDVNNQSPVFVEDIYSASVSENVSLGHHVITVVAEDMDLSPENS 2526

Query: 721  VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA--SPPLWN-D 777
             ++Y I+ G+D   F ++   GS    +  +  LD E+    Y L+I A     P+ N  
Sbjct: 2527 KINYFIESGNDQGKFKIDANDGS----ITVLERLDREA-TDTYTLIIGAVDNGEPVNNAT 2581

Query: 778  VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGN 835
              V I V D+ND++P+    Q      ++         V A D D+    +++Y I+SG 
Sbjct: 2582 AEVVIEVEDINDHSPIFDHVQYEGRIAENATASTYILTVHATDRDIGYNGEVEYSIISGT 2641

Query: 836  NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITE 889
             ++L  ++  +G++T+  +L+    +     V  +D G+    A + L    IT+
Sbjct: 2642 YSDLFAIDVVSGAVTVRGELDREEVERVEFTVQASDRGMENQLASVVLVTITITD 2696



 Score =  332 bits (816), Expect = 8e-89
 Identities = 251/744 (33%), Positives = 358/744 (48%), Gaps = 41/744 (5%)

Query: 134  ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV-IAKIKATDADVGANSAIRYAII 192
            AT+ V + D NDN PQF +  Y   V E   V ++ + + ++ ATDAD G N AI Y + 
Sbjct: 2167 ATVQVELTDANDNAPQFVQDRYQSRVWE---VPNSDIYVTQVSATDADEGTNGAIYYEVT 2223

Query: 193  GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252
             GNT   F+ID ++G V+  K+LDYE   SY L + A+DGGSP  + T  + I I DVND
Sbjct: 2224 SGNTDNAFAIDHVTGIVTTAKSLDYEIEDSYVLTVVARDGGSPQLTGTATMRIGIVDVND 2283

Query: 253  NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312
            N P F   +   SVSE++ +G S+  V A D+D   N + ++T      TGN      ID
Sbjct: 2284 NQPVF-VQMDPVSVSEDLGVGLSVTTVTATDSDTNPNIQYSFTS-----TGNPGGYFAID 2337

Query: 313  PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE 372
              SG +  +  LDRETQ  Y L + AT   D   + T T              F    Y+
Sbjct: 2338 QYSGIITLARSLDRETQDGYTLELEAT---DTEYTTTMTLEVIVTDENDNAPVFRQESYQ 2394

Query: 373  VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432
            V L E   P   VV + A  +D+D  L+ E+T        S       G+I   Q ++F 
Sbjct: 2395 VTLPELTQPNVAVVAVNA--SDKDIGLNAELTYSFVDSHPSFYIDPITGVIFTNQVIEFN 2452

Query: 433  Q-ERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
              E    L V+ATDSG    S+   V+I ITD NN +PVF    Y+ASV E+  +G  V+
Sbjct: 2453 DVETTIQLYVTATDSGAPALSEFVTVRIEITDVNNQSPVFVEDIYSASVSENVSLGHHVI 2512

Query: 490  VVSATDSDVG-INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
             V A D D+   N++I Y + S        +   +F I+   G+IT  + LDRE    Y 
Sbjct: 2513 TVVAEDMDLSPENSKINYFIES-------GNDQGKFKIDANDGSITVLERLDREATDTYT 2565

Query: 549  LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
            L + A D G P  + T +V I V D+ND+ P+F    Y   I E+A   T +  V ATD 
Sbjct: 2566 LIIGAVDNGEPVNNATAEVVIEVEDINDHSPIFDHVQYEGRIAENATASTYILTVHATDR 2625

Query: 609  DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ- 667
            D+G NG + Y +      +  F ID  SG +     LDRE V   +    A D G   Q 
Sbjct: 2626 DIGYNGEVEYSIISGTYSD-LFAIDVVSGAVTVRGELDREEVERVEFTVQASDRGMENQL 2684

Query: 668  SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
            +S V+V I I D N+ PP F      F + EN P+ T +    A D D G    + YSI+
Sbjct: 2685 ASVVLVTITITDFNEFPPYFPQLFYHFLVPENMPVETYVFTAGALDNDAGEYGELTYSIR 2744

Query: 728  GGDDSNS---FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEIL 783
            G   SN    F+++   G    E+ T    DYES    Y  V++A  +  L   ++ E+ 
Sbjct: 2745 GLGPSNGDDYFTIDPVTG----EVFTAAVFDYES-ANSYRFVVQAQDTGGLSISIQTEVN 2799

Query: 784  VTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDKLQYRILSGNNANLILL 842
            +T V++  P+  D +  F    D    G + G+V A DAD  +     ++         +
Sbjct: 2800 ITSVDEFPPMFNDQEYYF-EIGDGADAGDYVGQVTATDADGGE--DGVVIYSLTHEFFYI 2856

Query: 843  NETTGSMTLSPQLNTNVPKLATME 866
              TTG + ++  LN++  K   +E
Sbjct: 2857 EATTGIIKVAKPLNSSARKRRGLE 2880



 Score =  324 bits (797), Expect = 2e-86
 Identities = 262/890 (29%), Positives = 409/890 (45%), Gaps = 64/890 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND+ P+F++  Y A++ E +  GT V  + ATD D G NA++ Y I        
Sbjct: 493  IAVTDVNDNPPIFDLPLYHATIIEASEPGTPVKQVHATDADEGVNAQIIYRI-------- 544

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +PE              D F I+  SG + T   +DRE+     + V A+D+   +S  L
Sbjct: 545  SPEGTDYS---------DWFEINPMSGLVTTLQKVDREETGSVFLTVIASDEGE-IS--L 592

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            SS+  I++ I D NDN P F   +Y  S+ E+  +       ++ ATD D G+   + Y+
Sbjct: 593  SSSVIINITITDVNDNQPVFFPGSYNASILEEQEIP--YCFLQVNATDPDEGSAGQVTYS 650

Query: 191  IIGG--NTQMQFSIDSLSGDVSLVKTLDYEQ-VRSYRLVIRAQDGGSPSRSNTTQLLINI 247
                   T  QFSI+ L+GD+ ++  LD +     Y   ++A DGG        +++  +
Sbjct: 651  PSTDLVPTPSQFSINPLTGDLCVISRLDRDAGQEEYNFAVKATDGGGLMSHAFVRVI--L 708

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
             D+NDN P F +  ++  +  +  +G  +  V A D D      +TYT+   D + N D 
Sbjct: 709  EDINDNVPVFTSLNYRGHIEYDAALGTEVKLVVAEDRDAREFGRVTYTI---DSSTN-DG 764

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
               I+  +G +   G LD      Y L V ATDGG    +  A               F 
Sbjct: 765  TFAINQTTGLITLVGSLDWVQHPVYTLEVIATDGGGRTSANHAQVTITVAGPDTSPPEFE 824

Query: 368  PGQYEVELAEDEPPG-TPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
               Y   + E+        V     D      + Y +T G+    F I + +G  + T  
Sbjct: 825  SSSYAFSVQENAAQVLVGAVKAGHIDPGITFPITYTLTSGDPNDFFRINTTSGE-IFTRG 883

Query: 427  QPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPI 484
               D +Q+   ++T+ A  SG       VQ+NIT  D N+  P F       S+ E   I
Sbjct: 884  SGPDHEQQAFVLITIQAA-SGMPPTYDDVQVNITVIDVNDNVPQFMAQTARTSIPESTGI 942

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            G+++ V +A D D G N  + Y L+S   N         F I   TG I  NK +     
Sbjct: 943  GSSIYVATAMDLDSGDNGLVRYRLTSNPGN--------TFRIVEATGEIILNKEVSYNDQ 994

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
              + + + A D G PSL  +  + + ++DVNDN PVF    Y  +I+E+  + T V QV 
Sbjct: 995  LSFEVDIQAYDAGEPSLEGSLTLTVIILDVNDNGPVFTMGFYPVSILENLPISTPVVQVE 1054

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            ATD D G N  I Y L P + +   F + P  G + T + LDRE  +T  L  +A D G+
Sbjct: 1055 ATDNDRGANALITYTLTP-NNDSPYFAVFPREGWLYTRQVLDRELKSTFTLTIMASDSGS 1113

Query: 665  PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
            PPQ+S+  V + + D ND+ P F      F+I+EN P GT +  + A DPD GPN  V Y
Sbjct: 1114 PPQNSSATVQVTVVDANDNAPHFTKKSYHFHINENLPAGTEVDRVEAVDPDLGPNGQVTY 1173

Query: 725  SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVE 781
            ++     S  F+++     ++  + T   LD E+    Y L+IRA    +P L +   V 
Sbjct: 1174 TL---SPSGDFTID-----EEGVIRTTHPLDREA-AYSYRLIIRAVDGGNPALSSSATVY 1224

Query: 782  ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDAD--VTDKLQYRILSGNNAN 838
            I V D+NDNAPV    +    + ++  P G F   + A D D  V   + Y ++  +   
Sbjct: 1225 INVNDLNDNAPVFSQDRTYQASVREEQPAGEFVAWIIATDTDSGVLGNISYSLIDSSPKF 1284

Query: 839  LILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN-EIKAMMQLSVRLI 887
            +I   +++G ++ +  ++       T+ V   DG N  ++A   + VR++
Sbjct: 1285 II---DSSGVISTAAAIDREDESYYTLTVLAQDGGNPPMQATASVRVRIL 1331



 Score =  320 bits (787), Expect = 3e-85
 Identities = 259/877 (29%), Positives = 403/877 (45%), Gaps = 69/877 (7%)

Query: 15   DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
            D ND+ PVF    Y   +   A+ GT V  + A D+D  +   V YTI+  T D      
Sbjct: 710  DINDNVPVFTSLNYRGHIEYDAALGTEVKLVVAEDRDAREFGRVTYTIDSSTND------ 763

Query: 75   AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134
                           F I+  +G +    SLD  +   YT+ V ATD     S   ++ A
Sbjct: 764  -------------GTFAINQTTGLITLVGSLDWVQHPVYTLEVIATDGGGRTS---ANHA 807

Query: 135  TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194
             + + +   + + P+F   +Y  SV E+ +     ++  +KA   D G    I Y +  G
Sbjct: 808  QVTITVAGPDTSPPEFESSSYAFSVQENAAQV---LVGAVKAGHIDPGITFPITYTLTSG 864

Query: 195  NTQMQFSIDSLSGDV-SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDN 253
            +    F I++ SG++ +     D+EQ     + I+A  G  P+  +  Q+ I + DVNDN
Sbjct: 865  DPNDFFRINTTSGEIFTRGSGPDHEQQAFVLITIQAASGMPPTYDDV-QVNITVIDVNDN 923

Query: 254  APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313
             P+F     + S+ E+  IG SI    A D D G N  + Y +T     GN      I  
Sbjct: 924  VPQFMAQTARTSIPESTGIGSSIYVATAMDLDSGDNGLVRYRLTSN--PGNT---FRIVE 978

Query: 314  RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373
             +G +  + ++    Q  +++ + A D G+P    + T              F  G Y V
Sbjct: 979  ATGEIILNKEVSYNDQLSFEVDIQAYDAGEPSLEGSLTLTVIILDVNDNGPVFTMGFYPV 1038

Query: 374  ELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431
             + E+ P  TPVV + ATD D   +  + Y +T  N    F++  +   G +   Q LD 
Sbjct: 1039 SILENLPISTPVVQVEATDNDRGANALITYTLTPNNDSPYFAVFPR--EGWLYTRQVLDR 1096

Query: 432  KQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
            + +  + LT+ A+DSG   ++ +A VQ+ + DAN+ AP F    Y   + E+ P GT V 
Sbjct: 1097 ELKSTFTLTIMASDSGSPPQNSSATVQVTVVDANDNAPHFTKKSYHFHINENLPAGTEVD 1156

Query: 490  VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
             V A D D+G N Q+TY+LS              F I+ + G I T   LDRE    Y L
Sbjct: 1157 RVEAVDPDLGPNGQVTYTLSP----------SGDFTID-EEGVIRTTHPLDREAAYSYRL 1205

Query: 550  TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ-QLYTANIMEDALVGTSVSQVGATDA 608
             + A DGG P+LS +  V I+V D+NDN PVF Q + Y A++ E+   G  V+ + ATD 
Sbjct: 1206 IIRAVDGGNPALSSSATVYINVNDLNDNAPVFSQDRTYQASVREEQPAGEFVAWIIATDT 1265

Query: 609  DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
            D G+ G I Y L     +   F+ID +SGVI T  A+DRE  + + L  +A DGG PP  
Sbjct: 1266 DSGVLGNISYSLIDSSPK---FIID-SSGVISTAAAIDREDESYYTLTVLAQDGGNPPMQ 1321

Query: 669  STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
            +T  V ++I D+ND+ P+       F   EN    T +G + A D D G N  ++Y I  
Sbjct: 1322 ATASVRVRILDLNDNVPIAAMSAYIFTADENIQPPTVVGVVSASDMDVGDNGKIYYYITE 1381

Query: 729  GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWN-DVRVEILV 784
            G+D + + +    G    E+  +  +DYE     Y L I A     P   +  + V I +
Sbjct: 1382 GNDFDVWDVNHSSG----EVYNVRVVDYEM-AAHYTLTIIAQDNNVPQTHSTSISVTINI 1436

Query: 785  TDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILSGNNANLIL 841
             D NDN P   D  +I+   ++   +      V A DAD      ++Y IL+    +   
Sbjct: 1437 LDQNDNTPDF-DQDLIYLTLQENVGINHVLWTVSATDADSGANGLIRYTILT--EQDFFA 1493

Query: 842  LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKA 878
            ++E TG++     ++  +  +  + +   D    + A
Sbjct: 1494 VDEYTGTLRTIQNVDHEINHVFLLVIQAQDQAINVSA 1530



 Score =  309 bits (759), Expect = 6e-82
 Identities = 253/794 (31%), Positives = 374/794 (47%), Gaps = 57/794 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V+D ND  P FE   Y  +V E  + GT V  + A D D G N  + Y +        
Sbjct: 1644 IRVIDVNDQPPRFEQSIYVMNVSESQAPGTYVGMVVAIDGDSGVNGRITYEL-------- 1695

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             PE+            + +FRI+  +G + T+A LDRE+   Y V V A D A P     
Sbjct: 1696 -PEE----------IARGMFRINATTGEIRTKAILDREQRDSYVVTVYAMDGAFPAR--- 1741

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
               AT+ V ++D NDN P F+  T+ +++ E+ S     VI    ATDAD G N  + Y+
Sbjct: 1742 YDMATVLVYVMDVNDNNPTFAPPTFDITLPENQS---PGVIHNAIATDADEGPNGDLIYS 1798

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I GG+ +  FSI+  +G +  V  LD E   +Y L I A D G+  RS TT + + + D+
Sbjct: 1799 ITGGDPKNAFSINQSTGAIFTVGALDREDEATYTLTITATDQGTSPRSGTTTIRVTVTDL 1858

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN P F +  + +S+ E+  I  +I+ V A D DEG+N ++ YT+   D T  + L  +
Sbjct: 1859 NDNDPVFGSMSYYKSIPESTAINATILTVVATDDDEGLNGDVYYTL---DNT-TIGL-FS 1913

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPPRSATATXXXXXXXXXXXXXXFMPG 369
            IDP  G + T+G+ D E + +Y   VTATD G   PRS                  F   
Sbjct: 1914 IDPEHGEITTTGKFDYEKETRYTFQVTATDSGVFGPRSERVQVIIDISDVNDNAPVFKTI 1973

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
                 + +D    T V  + A   D+D+ ++ E+    T+   S       G+IT  + L
Sbjct: 1974 PIRANVTQDASSNTFVANVEAD--DKDSGVNGEVNYRFTQQSSSFAIDTVTGVIT-TKSL 2030

Query: 430  DFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
            +      Y L V A D G    S   +V++ +  + +    F    Y     E A  G  
Sbjct: 2031 N-PGTLFYHLEVMAFDLGSPSLSSNGIVEVWVGTSGSGGLQFGQQTYLVQPSEAADNGDV 2089

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
            VL +SA   D   +  I YSL S   N A     Q         A TT   LD ET    
Sbjct: 2090 VLSLSAFLPDGSSSNDIVYSLVSGNENGAFGIQVQAGGSAILVVADTTK--LDYETQPNI 2147

Query: 548  LLTVTAR---DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
             L   A    +   P     T V++ + D NDN P F Q  Y + + E       V+QV 
Sbjct: 2148 RLVAEAMRTPENSSPMYGYAT-VQVELTDANDNAPQFVQDRYQSRVWEVPNSDIYVTQVS 2206

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            ATDAD G NG I+YE+      + +F ID  +G++ T K+LD E   ++ L  VA DGG+
Sbjct: 2207 ATDADEGTNGAIYYEV-TSGNTDNAFAIDHVTGIVTTAKSLDYEIEDSYVLTVVARDGGS 2265

Query: 665  PPQSSTVIVHIKIEDINDSPPVF-ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
            P  + T  + I I D+ND+ PVF + D ++  +SE+  +G ++  + A D D  PN  + 
Sbjct: 2266 PQLTGTATMRIGIVDVNDNQPVFVQMDPVS--VSEDLGVGLSVTTVTATDSDTNPN--IQ 2321

Query: 724  YSIKG-GDDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRAASPPLWNDVRVE 781
            YS    G+    F+++   G     ++T+   LD E+ +  Y L + A        + +E
Sbjct: 2322 YSFTSTGNPGGYFAIDQYSG-----IITLARSLDRET-QDGYTLELEATDTEYTTTMTLE 2375

Query: 782  ILVTDVNDNAPVMK 795
            ++VTD NDNAPV +
Sbjct: 2376 VIVTDENDNAPVFR 2389



 Score =  299 bits (733), Expect = 9e-79
 Identities = 238/791 (30%), Positives = 371/791 (46%), Gaps = 64/791 (8%)

Query: 90  FRIDGRSGALLTRASLDREKVA--RYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
           F I+  +G + T A LDRE      + ++V A +  + +        TI +N  D NDN 
Sbjct: 122 FMIESDTGIITTGAVLDRETAPDQEFVIIVFAGEMFTAL------VVTIRLN--DTNDNN 173

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIK---ATDADVGANSAIRYAIIGGNTQMQFSID- 203
           P FS+   T  V E +     P + KI    ATDAD G N    Y I+GGN    F +D 
Sbjct: 174 PIFSQDNRTFEVTEAVQ----PYMTKINGVTATDADEGINGIQGYRIVGGNIDNTFDLDV 229

Query: 204 -----SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY 258
                 +  D+ + KTLD E +  Y L+I A DGG P  +  T + I + DVNDN+P F 
Sbjct: 230 RVRETGVYMDIVVNKTLDRETISMYTLIIEAYDGGDPRLTANTTVNIKVTDVNDNSPVFT 289

Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV 318
            + F  +++E+ P+  ++++V A D DEG+N E+ + +   D          IDP SG V
Sbjct: 290 LTSFTATINESAPVNTTVLQVTASDEDEGLNGEVVFNLQRDDGF------FRIDPASGIV 343

Query: 319 YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX-----XXXXXFMPGQYEV 373
           Y +  L+ E    +  LV A D  +PP S+                      F+P     
Sbjct: 344 YLNKVLNYEDAQAHDFLVIAQDKAEPPMSSQPAYVSIMVININEKPPSLEVLFLPDGGAS 403

Query: 374 ELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRG----LITVAQ 427
           +++E     T +  ++ TD D+     +   ITGG   G+F +   + +     + T A 
Sbjct: 404 QVSEAAVADTTLARISVTDPDDGVLTNVSMTITGG--AGQFDLQKNSNQVYFLIVATTAS 461

Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIG 485
             D ++   Y +++ ATD G     A   + I +TD N+  P+F+   Y A++ E +  G
Sbjct: 462 SFDREEVASYDISIRATDHGSPPQHAEENLTIAVTDVNDNPPIFDLPLYHATIIEASEPG 521

Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
           T V  V ATD+D G+NAQI Y +S E ++     +   F INP +G +TT + +DRE   
Sbjct: 522 TPVKQVHATDADEGVNAQIIYRISPEGTD-----YSDWFEINPMSGLVTTLQKVDREETG 576

Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
              LTV A D G  SLS +  + I++ DVNDN+PVF    Y A+I+E+  +     QV A
Sbjct: 577 SVFLTVIASDEGEISLSSSVIINITITDVNDNQPVFFPGSYNASILEEQEIPYCFLQVNA 636

Query: 606 TDADVGLNGRIHYELDPK-DREEGSFVIDPASGVIRTNKALDRES-VATHDLKAVAIDGG 663
           TD D G  G++ Y            F I+P +G +     LDR++    ++    A DGG
Sbjct: 637 TDPDEGSAGQVTYSPSTDLVPTPSQFSINPLTGDLCVISRLDRDAGQEEYNFAVKATDGG 696

Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
                S   V + +EDIND+ PVF S     +I  ++ +GT +  + A D D      V 
Sbjct: 697 --GLMSHAFVRVILEDINDNVPVFTSLNYRGHIEYDAALGTEVKLVVAEDRDAREFGRVT 754

Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMV-DLDY-ESPRKKYELVIR-AASPPLWNDVRV 780
           Y+I    +  +F++    G     L+T+V  LD+ + P    E++          N  +V
Sbjct: 755 YTIDSSTNDGTFAINQTTG-----LITLVGSLDWVQHPVYTLEVIATDGGGRTSANHAQV 809

Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA--YDADVTDKLQYRILSGNNAN 838
            I V   + + P  +     F+  ++   V   G V A   D  +T  + Y + SG+  +
Sbjct: 810 TITVAGPDTSPPEFESSSYAFSVQENAAQV-LVGAVKAGHIDPGITFPITYTLTSGDPND 868

Query: 839 LILLNETTGSM 849
              +N T+G +
Sbjct: 869 FFRINTTSGEI 879



 Score =  277 bits (680), Expect = 2e-72
 Identities = 239/797 (29%), Positives = 355/797 (44%), Gaps = 56/797 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND+SPVF +  + A++ E A   TTVL + A+D+D G N EV +         L
Sbjct: 276  IKVTDVNDNSPVFTLTSFTATINESAPVNTTVLQVTASDEDEGLNGEVVF--------NL 327

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
              +D               FRID  SG +     L+ E    +  LV A D+A P     
Sbjct: 328  QRDDG-------------FFRIDPASGIVYLNKVLNYEDAQAHDFLVIAQDKAEPPMS-- 372

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYT---VSVDEDISVTDNPVIAKIKATDADVGANSAI 187
            S  A + + +I+ N+  P            S   + +V D   +A+I  TD D G  + +
Sbjct: 373  SQPAYVSIMVININEKPPSLEVLFLPDGGASQVSEAAVADT-TLARISVTDPDDGVLTNV 431

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKT----LDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
               I GG  Q     +S      +V T     D E+V SY + IRA D GSP +     L
Sbjct: 432  SMTITGGAGQFDLQKNSNQVYFLIVATTASSFDREEVASYDISIRATDHGSPPQHAEENL 491

Query: 244  LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
             I + DVNDN P F   L+  ++ E    G  + +V A DADEGVNA++ Y ++ +  T 
Sbjct: 492  TIAVTDVNDNPPIFDLPLYHATIIEASEPGTPVKQVHATDADEGVNAQIIYRISPEG-TD 550

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
              D    I+P SG V T  ++DRE      L V A+D G+   S++              
Sbjct: 551  YSDW-FEINPMSGLVTTLQKVDREETGSVFLTVIASDEGEISLSSSVIINITITDVNDNQ 609

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGG--NTRGRFSITSQNG 419
              F PG Y   + E++      + + ATD DE +  ++ Y  +     T  +FSI    G
Sbjct: 610  PVFFPGSYNASILEEQEIPYCFLQVNATDPDEGSAGQVTYSPSTDLVPTPSQFSINPLTG 669

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479
               +      D  QE  Y   V ATD GG    A V++ + D N+  PVF +  Y   + 
Sbjct: 670  DLCVISRLDRDAGQE-EYNFAVKATDGGGLMSHAFVRVILEDINDNVPVFTSLNYRGHIE 728

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
             DA +GT V +V A D D     ++TY++ S       + +D  F IN  TG IT    L
Sbjct: 729  YDAALGTEVKLVVAEDRDAREFGRVTYTIDS-------STNDGTFAINQTTGLITLVGSL 781

Query: 540  DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
            D      Y L V A DGG  + ++   V I+V   + + P F+   Y  ++ E+A     
Sbjct: 782  DWVQHPVYTLEVIATDGGGRTSANHAQVTITVAGPDTSPPEFESSSYAFSVQENA-AQVL 840

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
            V  V A   D G+   I Y L   D  +  F I+  SG I T  +          L  + 
Sbjct: 841  VGAVKAGHIDPGITFPITYTLTSGDPND-FFRINTTSGEIFTRGSGPDHEQQAFVLITIQ 899

Query: 660  IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
               G PP    V V+I + D+ND+ P F +      I E++ IG++I    A D D G N
Sbjct: 900  AASGMPPTYDDVQVNITVIDVNDNVPQFMAQTARTSIPESTGIGSSIYVATAMDLDSGDN 959

Query: 720  AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR---AASPPLWN 776
             +V Y +   +  N+F +    G    E++   ++ Y + +  +E+ I+   A  P L  
Sbjct: 960  GLVRYRLT-SNPGNTFRIVEATG----EIILNKEVSY-NDQLSFEVDIQAYDAGEPSLEG 1013

Query: 777  DVRVEILVTDVNDNAPV 793
             + + +++ DVNDN PV
Sbjct: 1014 SLTLTVIILDVNDNGPV 1030



 Score =  273 bits (670), Expect = 4e-71
 Identities = 203/644 (31%), Positives = 311/644 (48%), Gaps = 55/644 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I ++D ND+ PVF +Q    SV E    G +V T+ ATD D   N +  +T       T
Sbjct: 2275 RIGIVDVNDNQPVF-VQMDPVSVSEDLGVGLSVTTVTATDSDTNPNIQYSFT------ST 2327

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             NP                 F ID  SG +    SLDRE    YT+ ++ATD        
Sbjct: 2328 GNPGG--------------YFAIDQYSGIITLARSLDRETQDGYTLELEATDT------E 2367

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             ++T T+ V + D+NDN P F +++Y V++ E      N  +  + A+D D+G N+ + Y
Sbjct: 2368 YTTTMTLEVIVTDENDNAPVFRQESYQVTLPE--LTQPNVAVVAVNASDKDIGLNAELTY 2425

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVR-SYRLVIRAQDGGSPSRSNTTQLLINIR 248
            + +  ++   F ID ++G +   + +++  V  + +L + A D G+P+ S    + I I 
Sbjct: 2426 SFV--DSHPSFYIDPITGVIFTNQVIEFNDVETTIQLYVTATDSGAPALSEFVTVRIEIT 2483

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYTGNVDL 307
            DVN+ +P F   ++  SVSENV +G+ ++ V A D D    N+++ Y +     +GN   
Sbjct: 2484 DVNNQSPVFVEDIYSASVSENVSLGHHVITVVAEDMDLSPENSKINYFIE----SGNDQG 2539

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
               ID   G +    +LDRE    Y L++ A D G+P  +ATA               F 
Sbjct: 2540 KFKIDANDGSITVLERLDREATDTYTLIIGAVDNGEPVNNATAEVVIEVEDINDHSPIFD 2599

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITV 425
              QYE  +AE+    T ++T+ ATD D   +  + Y I  G     F+I   +  G +TV
Sbjct: 2600 HVQYEGRIAENATASTYILTVHATDRDIGYNGEVEYSIISGTYSDLFAIDVVS--GAVTV 2657

Query: 426  AQPLDFKQERRYVLTVSATDSGGRSDTA---MVQINITDANNYAPVFENAPYTASVFEDA 482
               LD ++  R   TV A+D G  +  A   +V I ITD N + P F    Y   V E+ 
Sbjct: 2658 RGELDREEVERVEFTVQASDRGMENQLASVVLVTITITDFNEFPPYFPQLFYHFLVPENM 2717

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
            P+ T V    A D+D G   ++TYS    I     ++ D  F I+P TG + T  + D E
Sbjct: 2718 PVETYVFTAGALDNDAGEYGELTYS----IRGLGPSNGDDYFTIDPVTGEVFTAAVFDYE 2773

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
            + + Y   V A+D G  S+S  T+V I+ VD  +  P+F  Q Y   I + A  G  V Q
Sbjct: 2774 SANSYRFVVQAQDTGGLSISIQTEVNITSVD--EFPPMFNDQEYYFEIGDGADAGDYVGQ 2831

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646
            V ATDAD G +G + Y L  +      F I+  +G+I+  K L+
Sbjct: 2832 VTATDADGGEDGVVIYSLTHE-----FFYIEATTGIIKVAKPLN 2870



 Score =  200 bits (488), Expect = 4e-49
 Identities = 169/474 (35%), Positives = 223/474 (47%), Gaps = 40/474 (8%)

Query: 377 EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ--E 434
           E++P GT V +L      +D       T  N    F I S  G  +IT    LD +   +
Sbjct: 92  ENQPVGTFVGSL-----QDDTSFGSPFTTLNPSAEFMIESDTG--IITTGAVLDRETAPD 144

Query: 435 RRYVLTVSATDSGGRSDTAMV-QINITDANNYAPVFENAPYTASVFEDA-PIGTTVLVVS 492
           + +V+ V A    G   TA+V  I + D N+  P+F     T  V E   P  T +  V+
Sbjct: 145 QEFVIIVFA----GEMFTALVVTIRLNDTNDNNPIFSQDNRTFEVTEAVQPYMTKINGVT 200

Query: 493 ATDSDVGINAQITYSL-SSEISNEAVAHHDQQFVINPQTGA---ITTNKLLDRETMSGYL 548
           ATD+D GIN    Y +    I N      D    +  +TG    I  NK LDRET+S Y 
Sbjct: 201 ATDADEGINGIQGYRIVGGNIDNT----FDLDVRVR-ETGVYMDIVVNKTLDRETISMYT 255

Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
           L + A DGG P L+  T V I V DVNDN PVF    +TA I E A V T+V QV A+D 
Sbjct: 256 LIIEAYDGGDPRLTANTTVNIKVTDVNDNSPVFTLTSFTATINESAPVNTTVLQVTASDE 315

Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
           D GLNG + + L    R++G F IDPASG++  NK L+ E    HD   +A D   PP S
Sbjct: 316 DEGLNGEVVFNL---QRDDGFFRIDPASGIVYLNKVLNYEDAQAHDFLVIAQDKAEPPMS 372

Query: 669 S-TVIVHIKIEDINDSPP----VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
           S    V I + +IN+ PP    +F  D     +SE +   TT+  I   DPD+G    V 
Sbjct: 373 SQPAYVSIMVININEKPPSLEVLFLPDGGASQVSEAAVADTTLARISVTDPDDGVLTNVS 432

Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRV 780
            +I GG         + Q        T    D E     Y++ IRA    SPP   +  +
Sbjct: 433 MTITGGAGQFDLQKNSNQVYFLIVATTASSFDREEV-ASYDISIRATDHGSPPQHAEENL 491

Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRI 831
            I VTDVNDN P+  D  +      +    G P  +V A DAD  V  ++ YRI
Sbjct: 492 TIAVTDVNDNPPIF-DLPLYHATIIEASEPGTPVKQVHATDADEGVNAQIIYRI 544



 Score =  167 bits (407), Expect = 3e-39
 Identities = 137/453 (30%), Positives = 205/453 (45%), Gaps = 37/453 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIG-KNAEVEYTIELVTAD 68
            +I + D N+ SPVF    Y ASV E  S G  V+T+ A D D+  +N+++ Y IE     
Sbjct: 2479 RIEITDVNNQSPVFVEDIYSASVSENVSLGHHVITVVAEDMDLSPENSKINYFIE----- 2533

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
              +  D            Q  F+ID   G++     LDRE    YT+++ A D   PV+ 
Sbjct: 2534 --SGND------------QGKFKIDANDGSITVLERLDREATDTYTLIIGAVDNGEPVN- 2578

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
              ++TA + + + D ND+ P F    Y   + E  + T +  I  + ATD D+G N  + 
Sbjct: 2579 --NATAEVVIEVEDINDHSPIFDHVQYEGRIAE--NATASTYILTVHATDRDIGYNGEVE 2634

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR-SNTTQLLINI 247
            Y+II G     F+ID +SG V++   LD E+V      ++A D G  ++ ++   + I I
Sbjct: 2635 YSIISGTYSDLFAIDVVSGAVTVRGELDREEVERVEFTVQASDRGMENQLASVVLVTITI 2694

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
             D N+  P F    +   V EN+P+   +    A D D G   ELTY++       N D 
Sbjct: 2695 TDFNEFPPYFPQLFYHFLVPENMPVETYVFTAGALDNDAGEYGELTYSIRGLG-PSNGDD 2753

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
              TIDP +G V+T+   D E+   Y+ +V A D G    S +                F 
Sbjct: 2754 YFTIDPVTGEVFTAAVFDYESANSYRFVVQAQDTGG--LSISIQTEVNITSVDEFPPMFN 2811

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITV 425
              +Y  E+ +    G  V  +TATDAD  ED  + Y +    T   F I +    G+I V
Sbjct: 2812 DQEYYFEIGDGADAGDYVGQVTATDADGGEDGVVIYSL----THEFFYIEATT--GIIKV 2865

Query: 426  AQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN 458
            A+PL+    +R  L    T    R      Q N
Sbjct: 2866 AKPLNSSARKRRGLEDRFTHRSRREIDLSAQSN 2898



 Score = 40.7 bits (91), Expect = 0.57
 Identities = 53/228 (23%), Positives = 94/228 (41%), Gaps = 24/228 (10%)

Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747
           + D L + + EN P+GT +G ++       P   +       + S  F +E    SD   
Sbjct: 82  QQDLLYYSVKENQPVGTFVGSLQDDTSFGSPFTTL-------NPSAEFMIE----SDTGI 130

Query: 748 LVTMVDLDYE-SPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKD 806
           + T   LD E +P +++ +++ A    ++  + V I + D NDN P+       F   + 
Sbjct: 131 ITTGAVLDRETAPDQEFVIIVFAGE--MFTALVVTIRLNDTNDNNPIFSQDNRTFEVTEA 188

Query: 807 CFP-VGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLN---ETTG---SMTLSPQLNT 857
             P +     V A DAD  +     YRI+ GN  N   L+     TG    + ++  L+ 
Sbjct: 189 VQPYMTKINGVTATDADEGINGIQGYRIVGGNIDNTFDLDVRVRETGVYMDIVVNKTLDR 248

Query: 858 NVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTA 905
               + T+ +   DG  + +     +V +   ++  NS    L   TA
Sbjct: 249 ETISMYTLIIEAYDG-GDPRLTANTTVNIKVTDVNDNSPVFTLTSFTA 295



 Score = 38.7 bits (86), Expect = 2.3
 Identities = 17/56 (30%), Positives = 32/56 (57%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
            I  ++N+   ++  P+F  Q+Y   + +GA +G  V  + ATD D G++  V Y++
Sbjct: 2794 IQTEVNITSVDEFPPMFNDQEYYFEIGDGADAGDYVGQVTATDADGGEDGVVIYSL 2849


>UniRef50_Q6V0I7 Cluster: FAT tumor suppressor homolog 4; n=35;
            Euteleostomi|Rep: FAT tumor suppressor homolog 4 - Homo
            sapiens (Human)
          Length = 3222

 Score =  397 bits (977), Expect = e-108
 Identities = 282/857 (32%), Positives = 427/857 (49%), Gaps = 73/857 (8%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            I    N+LD ND+ P+F +  Y  S+ E    G+TVL    TD D G N+++ Y+I   +
Sbjct: 226  IRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSI--AS 283

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
             D+L                   F +D ++G L    +LDRE  + Y ++V+  D     
Sbjct: 284  GDSLGQ-----------------FTVD-KNGVLKVLKALDRESQSFYNLVVQVHDLPQIP 325

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
            + R +STA + + ++D NDN P F     T  + E+  +  + V+ K +ATD D G NS 
Sbjct: 326  ASRFTSTAQVSIILLDVNDNPPTFLSPKLTY-IPENTPI--DTVVFKAQATDPDSGPNSY 382

Query: 187  IRYAIIG--GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
            I Y ++   GN   +FSI ++ G+V L   LD E+V +Y L + A D G PS S++T+++
Sbjct: 383  IEYTLLNPLGN---KFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVV 439

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
            + + D+NDN P F  +L++  ++EN   G  I++V A D DEG N ++ Y + +    GN
Sbjct: 440  VMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVN----GN 495

Query: 305  VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
             +    ID  +G +  +  LDRE    Y L V ATD G  PR+ T+T             
Sbjct: 496  TNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVP 555

Query: 365  XFMPGQYEVELAED--EPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGR 420
             F    Y V + E+    P T ++ + A D D   +++L Y + GGN    F++++    
Sbjct: 556  VFELSPYSVNVPENLGTLPRT-ILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLSAS--- 611

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASV 478
            G + V Q LD + + R+VL ++ATDSG  + T    IN+   D N+  P F +  Y  ++
Sbjct: 612  GELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFASKAYFTTI 671

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             EDAP GT VL+V+A+D+D   NA I            +   + QF INP TG I T+ L
Sbjct: 672  PEDAPTGTDVLLVNASDADASKNAVIR-----------IIGGNSQFTINPSTGQIITSAL 720

Query: 539  LDRETMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
            LDRET   Y L V   D G P  LS +T V ++V DVNDN P F+   Y  +I    L G
Sbjct: 721  LDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPG 780

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
            + V  V  TDAD+G N  +HY L  ++ E+  F IDP  G I     L+  S  T  +  
Sbjct: 781  SFVFAVTVTDADIGPNSELHYSLSGRNSEK--FHIDPLRGAIMAAGPLNGASEVTFSVHV 838

Query: 658  VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
               DGG+ P++ +  V ++  +  D P V   +  TF   EN P+ + +  I        
Sbjct: 839  K--DGGSFPKTDSTTVTVRFVNKADFPKVRAKE-QTFMFPENQPVSSLVTTITGSSLRGE 895

Query: 718  PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPL 774
            P   + Y I  G+  N+F ++   G    ++     LD+E   +KY + I A     PP 
Sbjct: 896  P---MSYYIASGNLGNTFQIDQLTG----QVSISQPLDFEK-IQKYVVWIEARDGGFPPF 947

Query: 775  WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRIL 832
             +  +++I V DVNDNAP+ K+   I    ++  P      V A D D     +L Y I+
Sbjct: 948  SSYEKLDITVLDVNDNAPIFKEDPFISEILENLSP-RKILTVSAMDKDSGPNGQLDYEIV 1006

Query: 833  SGNNANLILLNETTGSM 849
            +GN  N   +N  TG +
Sbjct: 1007 NGNMENSFSINHATGEI 1023



 Score =  386 bits (951), Expect = e-105
 Identities = 421/1648 (25%), Positives = 689/1648 (41%), Gaps = 184/1648 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND++P F    Y     E    G+ V  + ATD D G N +V Y I+       
Sbjct: 1158 IFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIK------- 1210

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA--------RYTVLVKATDQ 122
                             + FRI+  +G +  +  L  + V         R++ +V ++D+
Sbjct: 1211 --------------SQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDR 1256

Query: 123  ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
              P    L S  T+ +NI+D NDN PQF +  Y   V +++ V    +I      D D G
Sbjct: 1257 GKP---SLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKV-GTKLIRVTAIDDKDFG 1312

Query: 183  ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
             NS + Y I   N   +F +D+ +G +S+  +L  +  +++ + + A+D G+P  S+   
Sbjct: 1313 LNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQAT 1372

Query: 243  LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
            + I + + N + P F  S    ++ E+  IG  +  V A D D  +N  + Y+++    +
Sbjct: 1373 VHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSIS----S 1428

Query: 303  GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
            GN +    I+  +G +  +  LD E   K+++ ++A DGG   R+   +           
Sbjct: 1429 GNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDN 1488

Query: 363  XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422
               F+   Y   + E+ P GT V+ L ATDAD         T  ++     +   N  G+
Sbjct: 1489 SPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPN-TGV 1547

Query: 423  ITVAQPLDFKQERRYVLTVSATD--SGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
            IT    LDF+ ++ Y LTV A +     R   A V I +   N Y P F +  Y   + E
Sbjct: 1548 ITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISE 1607

Query: 481  DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
             AP GT V  V A+D D+G + ++ Y +      +        F IN +TG I  + +LD
Sbjct: 1608 AAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKG-------FQINKKTGQIYVSGILD 1660

Query: 541  RETMSGYLLTVTARD-GGVPSLS-DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            RE      L V A++ G +     D   V ++V+D ND  P+F   +Y+  I E   +GT
Sbjct: 1661 REKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGT 1719

Query: 599  SVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
             V+ V A D+D +    R  Y +     E G+F I+P +G I     LDRE++  ++L  
Sbjct: 1720 HVTFVSAFDSDSIPSWSRFSYFIG-SGNENGAFSINPQTGQITVTAELDRETLPIYNLSV 1778

Query: 658  VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
            +A+D GTP  + +  + + +EDIND+ P+         + EN   GT +  +++ DPD  
Sbjct: 1779 LAVDSGTPSATGSASLLVTLEDINDNGPMLTVS--EGEVMENKRPGTLVMTLQSTDPDLP 1836

Query: 718  PNA--VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--PP 773
            PN     +Y +  G  ++ FSL T        L T  ++D E     Y  V+   S  P 
Sbjct: 1837 PNQGPFTYYLLSTGPATSYFSLSTA-----GVLSTTREIDREQIADFYLSVVTKDSGVPQ 1891

Query: 774  LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILS 833
            + +   V I V D NDN    +  +I  N Y + FP G  G V   D DV D     + S
Sbjct: 1892 MSSTGTVHITVIDQNDNPSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDVLDSFHCSLTS 1951

Query: 834  GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE-IKAMMQLSVRLITEEML 892
            G   +L  +   T  +   P+       L  +     DGV+  + + +++     +   +
Sbjct: 1952 G-VTSLFSIPGGTCDLNSQPRSTDGTFDLTVLS---NDGVHSTVTSNIRVFFAGFSNATV 2007

Query: 893  LNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFS 952
             NSI +RL   T + FL+     F+   ++ +      + ++S  ++ + T  +      
Sbjct: 2008 DNSILLRLGVPTVKDFLTNHYLHFLRIASSQLTGLGTAVQLYSAYEENNRTFLL------ 2061

Query: 953  ARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEE 1012
                     V  + + + +P+ +       +  L R + V+V   D + CVH PC N   
Sbjct: 2062 -------AAVKRNHNQYVNPSGVATFFESIKEILLRQSGVKVESVDHDSCVHGPCQNGGS 2114

Query: 1013 CLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKA---------- 1062
            CL  L   +      S  V+     P+  F C+C  G+ G  CE  + +           
Sbjct: 2115 CLRRLAVSSVLKSRESLPVIIVANEPLQPFLCKCLPGYAGSWCEIDIDECLPSPCHSGGT 2174

Query: 1063 --------SCEV-DG-DGSIC-RSGSQCV-ARREGGILCQ------GCSIDAAYTTAV-- 1102
                    SC   DG  G  C R  ++C+ +  + G +CQ       C     YT     
Sbjct: 2175 CHNLVGGFSCSCPDGFTGRACERDINECLQSPCKNGAICQNFPGSFNCVCKTGYTGVFGK 2234

Query: 1103 -CELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYN--GRYNERHDFLALEL 1159
             CEL +  F   S++ FP L   +  ++ +KFAT  +  LLLYN   +  +R +FLALE+
Sbjct: 2235 HCELNSYGFEELSYMEFPSLDPNNN-YIYVKFATIKSHALLLYNYDNQTGDRAEFLALEI 2293

Query: 1160 VSSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKVL 1219
                        LRFS++LG G  ++T    V DG +HTV         ++ +D C +  
Sbjct: 2294 AEER--------LRFSYNLGSGTYKLTTMKKVSDGHFHTVIARRAGMAASLTVDSCSENQ 2345

Query: 1220 SLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNK 1279
               G           ++T  V P R      T      L   LQ  G         V++ 
Sbjct: 2346 E-PGYCTVSNVAVSDDWTLDVQPNRV-----TVGGIRSLEPILQRRG--------HVESH 2391

Query: 1280 DFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDC 1339
            DFVGCI +F ++ + ++ +  +A  G L    +  S      C+   +C  +  T   D 
Sbjct: 2392 DFVGCIMEFAVNGRPLEPSQALAAQGILDQYGDFISY-----CFKEKKCKKVCFTVTPDT 2446

Query: 1340 KEGHTGKDCAD---STGPPWRFGGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMSIQ 1396
                 GK   D   S      +     L    +L P  +  L  +  RTR  +  ++ IQ
Sbjct: 2447 ALSLEGKGRLDYHMSQNEKREYLLRQSLR-GAMLEPFGVNSLE-VKFRTRSENGVLIHIQ 2504

Query: 1397 ---------LKSGLLHYSYN----GET-MYLPMATLSDGAWHRIEIKWLGTDISVTVD-- 1440
                     +K+G ++++ +    G+    +P   ++DG WH   I   GT   ++VD  
Sbjct: 2505 ESSNYTTVKIKNGKVYFTSDAGIAGKVERNIPEVYVADGHWHTFLIGKNGTATVLSVDRI 2564

Query: 1441 YGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGLLASDVGFFEGCIQDVRIG-------T 1493
            Y  R ++ P       G  +  I +GG+        +    F+GCI  +  G        
Sbjct: 2565 YN-RDIIHP--TQDFGGLDVLTISLGGIPPNQAHRDAQTAGFDGCIASMWYGGESLPFSG 2621

Query: 1494 AQSLLNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACE 1553
              SL +      +V+ GC+    C  + C     C+  W +  C      V P     C 
Sbjct: 2622 KHSLASISKTDPSVKIGCRGPNICASNPCWGDLLCINQWYAYRC------VPP---GDCA 2672

Query: 1554 LGPC-GAARCVPDQTPKGYSCACEPGYT 1580
              PC     C P     G++C+C   +T
Sbjct: 2673 SHPCQNGGSCEPG-LHSGFTCSCPDSHT 2699



 Score =  371 bits (912), Expect = e-100
 Identities = 283/876 (32%), Positives = 429/876 (48%), Gaps = 72/876 (8%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +I + D ND+ PVF     + +V E    G+ ++ L A D D G NA V YTI +  AD 
Sbjct: 25  EITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTI-ISGAD- 82

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                             D FRID  SG L+    LDRE+ ++Y++LV+A D        
Sbjct: 83  ------------------DSFRIDPESGDLIATRRLDRERRSKYSLLVRADDGLQ----- 119

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            SS   I++ + D ND+ P+FS   Y+  + ED       ++A I ATD D G N  I Y
Sbjct: 120 -SSDMRINITVSDVNDHTPKFSRPVYSFDIPED--TIPGSLVAAILATDDDSGVNGEITY 176

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            +   +    F ++ ++G  +L + LDYE  + Y L +RA+DGG   +  T ++  NI D
Sbjct: 177 IVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGG--GQFTTIRVYFNILD 234

Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
           VNDN P F  + +  S+ EN+P+G +++     DAD+G+N++LTY++   D  G      
Sbjct: 235 VNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQ----F 290

Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRS---ATATXXXXXXXXXXXXXXF 366
           T+D ++G +     LDRE+Q+ Y L+V   D    P S   +TA               F
Sbjct: 291 TVD-KNGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTF 349

Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG-RFSITSQNGRGLITV 425
           +  +    + E+ P  T V    ATD D     + E T  N  G +FSI + +G   + +
Sbjct: 350 LSPKL-TYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGE--VRL 406

Query: 426 AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
              LD ++   Y LTV ATD G    S +  V + + D N+  P+F  A Y   + E+  
Sbjct: 407 TGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTL 466

Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
            GT ++ V A D D G N Q+ Y + +  +N       Q+F I+  TGAIT  K LDRE 
Sbjct: 467 TGTDIIQVFAADGDEGTNGQVRYGIVNGNTN-------QEFRIDSVTGAITVAKPLDREK 519

Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED-ALVGTSVSQ 602
              Y LTV A D G    +DT+ V I ++D+ND  PVF+   Y+ N+ E+   +  ++ Q
Sbjct: 520 TPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQ 579

Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
           V A D D G N ++ Y L     E+ +F +  ASG +   ++LDRE+     L   A D 
Sbjct: 580 VVARDDDRGSNSKLSYVLF-GGNEDNAFTLS-ASGELGVTQSLDRETKERFVLMITATDS 637

Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
           G+P  + T  +++ ++D+ND+ P F S      I E++P GT +  + A D D   NAV+
Sbjct: 638 GSPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVI 697

Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI---RAASP-PLWNDV 778
              I GG  ++ F++    G    +++T   LD E+ +  Y LV+    A SP PL +  
Sbjct: 698 R--IIGG--NSQFTINPSTG----QIITSALLDRET-KDNYTLVVVCSDAGSPEPLSSST 748

Query: 779 RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNN 836
            V + VTDVNDN P  +    + +      P      V   DAD+    +L Y  LSG N
Sbjct: 749 SVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYS-LSGRN 807

Query: 837 ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
           +    ++   G++  +  LN       T  V V DG
Sbjct: 808 SEKFHIDPLRGAIMAAGPLNG--ASEVTFSVHVKDG 841



 Score =  350 bits (861), Expect = 3e-94
 Identities = 252/770 (32%), Positives = 374/770 (48%), Gaps = 48/770 (6%)

Query: 114 TVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK 173
           TV+      A P++   +    + + + D NDN P F      ++V+E+I   D   I +
Sbjct: 4   TVVAVGDTLAQPLA--AAEVFIVEITLQDINDNPPVFPTDMLDLTVEENIG--DGSKIMQ 59

Query: 174 IKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233
           + A DAD GAN+ + Y II G     F ID  SGD+   + LD E+   Y L++RA DG 
Sbjct: 60  LTAMDADEGANALVTYTIISGADD-SFRIDPESGDLIATRRLDRERRSKYSLLVRADDG- 117

Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293
              +S+  ++ I + DVND+ P+F   ++   + E+   G  +  + A D D GVN E+T
Sbjct: 118 --LQSSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEIT 175

Query: 294 YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353
           Y + + D  G   L    +P +G    +  LD E Q  Y L V A DGG   +  T    
Sbjct: 176 YIVNEDDEDGIFFL----NPITGVFNLTRLLDYEVQQYYILTVRAEDGGG--QFTTIRVY 229

Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGR 411
                       F    Y   L E+ P G+ V+    TDAD+  +++L Y I  G++ G+
Sbjct: 230 FNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQ 289

Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATD-----SGGRSDTAMVQINITDANNYA 466
           F++      G++ V + LD + +  Y L V   D     +   + TA V I + D N+  
Sbjct: 290 FTVDKN---GVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNP 346

Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
           P F + P    + E+ PI T V    ATD D G N+ I Y+L + + N+        F I
Sbjct: 347 PTFLS-PKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNK--------FSI 397

Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586
               G +     LDRE +S Y LTV A D G PSLS +T+V + V+D+NDN P+F Q LY
Sbjct: 398 GTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALY 457

Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646
              I E+ L GT + QV A D D G NG++ Y +   +  +  F ID  +G I   K LD
Sbjct: 458 KVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQ-EFRIDSVTGAITVAKPLD 516

Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN-SPIGTT 705
           RE   T+ L   A D G+ P++ T  V I + DIND  PVFE    +  + EN   +  T
Sbjct: 517 REKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRT 576

Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765
           I ++ A D D G N+ + Y + GG++ N+F+L     S   EL     LD E+ ++++ L
Sbjct: 577 ILQVVARDDDRGSNSKLSYVLFGGNEDNAFTL-----SASGELGVTQSLDRET-KERFVL 630

Query: 766 VIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDA 821
           +I A    SP L     + ++V DVNDN P     +  F    +  P G     V A DA
Sbjct: 631 MITATDSGSPALTGTGTINVIVDDVNDNVPTFAS-KAYFTTIPEDAPTGTDVLLVNASDA 689

Query: 822 DVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
           D +     RI+ GN+     +N +TG +  S  L+       T+ V  +D
Sbjct: 690 DASKNAVIRIIGGNSQ--FTINPSTGQIITSALLDRETKDNYTLVVVCSD 737



 Score =  347 bits (853), Expect = 3e-93
 Identities = 248/829 (29%), Positives = 406/829 (48%), Gaps = 48/829 (5%)

Query: 54   KNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARY 113
            +N  V   +  +T  +L  E            + + F+ID  +G +     LD EK+ +Y
Sbjct: 876  ENQPVSSLVTTITGSSLRGEPMSYYIASGN--LGNTFQIDQLTGQVSISQPLDFEKIQKY 933

Query: 114  TVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK 173
             V ++A D   P     SS   + + ++D NDN P F E  +   + E++S      I  
Sbjct: 934  VVWIEARDGGFPP---FSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPRK---ILT 987

Query: 174  IKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233
            + A D D G N  + Y I+ GN +  FSI+  +G++  V+ LD E+V  Y L I++ D G
Sbjct: 988  VSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKG 1047

Query: 234  SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293
            SPS+S + +++INI D NDNAPRF + +F   V EN P+GY++ RV   D D G+NA   
Sbjct: 1048 SPSQSTSVKVMINILDENDNAPRF-SQIFSAHVPENSPLGYTVTRVTTSDEDIGINAISR 1106

Query: 294  YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353
            Y++ D        LP TI+P +G +  S  L+RE   +Y++ V+A D G    + +    
Sbjct: 1107 YSIMD------ASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSG---WTVSTDVT 1157

Query: 354  XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGR 411
                        F    Y ++  E    G+ V  + ATD DE  + ++ Y I   +   R
Sbjct: 1158 IFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEYFR 1217

Query: 412  FSITSQN--GRGLITVAQPLDFKQE--RRYVLTVSATDSGGRS--DTAMVQINITDANNY 465
             + T+     + ++       F      R+   V+++D G  S      V INI D+N+ 
Sbjct: 1218 INATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDN 1277

Query: 466  APVFENAPYTASVFEDAPIGTTVLVVSA-TDSDVGINAQITYSLSSEISNEAVAHHDQQF 524
            AP F  + Y   V ++  +GT ++ V+A  D D G+N+++ Y +S++       +H  +F
Sbjct: 1278 APQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISND-------NHLGKF 1330

Query: 525  VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584
             ++  TG I+    L  +    + +TVTA+D G P LS    V I+V + N + P F Q 
Sbjct: 1331 KLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQS 1390

Query: 585  LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA 644
              +A I E   +G+ V  V A D D  +NG I Y +     EEG F I+ ++G++   KA
Sbjct: 1391 HMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSIS-SGNEEGIFAINSSTGILTLAKA 1449

Query: 645  LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
            LD E    H++   AIDGG   ++    V + + D+ND+ PVF SD     + EN+P GT
Sbjct: 1450 LDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGT 1509

Query: 705  TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764
            T+  + A D D G NAV+ Y+++   DS+ F ++   G     + T   LD+E+ ++ Y 
Sbjct: 1510 TVIHLNATDADSGTNAVIAYTVQ-SSDSDLFVIDPNTG----VITTQGFLDFET-KQSYH 1563

Query: 765  LVIRAASPP---LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYD 820
            L ++A + P     +   V I +   N+  P     ++ +    +  P G   G V A D
Sbjct: 1564 LTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVS-KLYYFEISEAAPKGTIVGEVFASD 1622

Query: 821  ADV-TD-KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867
             D+ TD ++ Y I   +      +N+ TG + +S  L+    +  +++V
Sbjct: 1623 RDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKV 1671



 Score =  345 bits (847), Expect = 1e-92
 Identities = 256/887 (28%), Positives = 438/887 (49%), Gaps = 69/887 (7%)

Query: 4    PFCIHQQ--INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
            PF  +++  I VLD ND++P+F+   + + + E  S    +LT+ A D+D G N +++Y 
Sbjct: 946  PFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSP-RKILTVSAMDKDSGPNGQLDY- 1003

Query: 62   IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121
             E+V  +                 +++ F I+  +G + +   LDREKV+ Y + +K++D
Sbjct: 1004 -EIVNGN-----------------MENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSD 1045

Query: 122  QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181
            + SP     S++  + +NI+D+NDN P+FS+  ++  V E+  +     + ++  +D D+
Sbjct: 1046 KGSPSQ---STSVKVMINILDENDNAPRFSQ-IFSAHVPENSPL--GYTVTRVTTSDEDI 1099

Query: 182  GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
            G N+  RY+I+  +  + F+I+  +GD+ + + L+ E    YR+ + A D G    + +T
Sbjct: 1100 GINAISRYSIM--DASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSG---WTVST 1154

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM-TDKD 300
             + I + D+NDNAPRF  + +     E   IG  + +V A D DEG N ++ Y + +  +
Sbjct: 1155 DVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSE 1214

Query: 301  Y------TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354
            Y      TG +     +  ++   +++  ++R     +  +VT++D G P   +  T   
Sbjct: 1215 YFRINATTGEIFNKQILKYQNVTGFSNVNINR-----HSFIVTSSDRGKPSLISETTVTI 1269

Query: 355  XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE---DNRLHYEITGGNTRGR 411
                       F+  +Y   + ++   GT ++ +TA D  +   ++ + Y I+  N  G+
Sbjct: 1270 NIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGK 1329

Query: 412  FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVF 469
            F +   N  G I+VA  L     + + +TV+A D G    S  A V I +T+ N + P F
Sbjct: 1330 FKL--DNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEF 1387

Query: 470  ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
              +  +A++ E   IG+ V  VSA D D  +N  I YS+SS   NE     +  F IN  
Sbjct: 1388 SQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISS--GNE-----EGIFAINSS 1440

Query: 530  TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589
            TG +T  K LD E    + +T++A DGG  + +    V ++V+DVNDN PVF    Y   
Sbjct: 1441 TGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPT 1500

Query: 590  IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES 649
            ++E+A  GT+V  + ATDAD G N  I Y +   D +   FVIDP +GVI T   LD E+
Sbjct: 1501 VLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSD--LFVIDPNTGVITTQGFLDFET 1558

Query: 650  VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
              ++ L   A +     + S   V+I+++  N+  P F S    F ISE +P GT +GE+
Sbjct: 1559 KQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEV 1618

Query: 710  RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
             A D D G +  VHY I G      F +  + G  +  +  ++D + E  R   +++ + 
Sbjct: 1619 FASDRDLGTDGEVHYLIFGNSRKKGFQINKKTG--QIYVSGILDREKEE-RVSLKVLAKN 1675

Query: 770  ASPPLWNDV-RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR-VPAYDADVT--- 824
                   D+  V + VT ++ N P +    I      +  P+G     V A+D+D     
Sbjct: 1676 FGSIRGADIDEVTVNVTVLDANDPPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSW 1735

Query: 825  DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
             +  Y I SGN      +N  TG +T++ +L+     +  + V   D
Sbjct: 1736 SRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVD 1782



 Score =  338 bits (832), Expect = 9e-91
 Identities = 252/802 (31%), Positives = 396/802 (49%), Gaps = 70/802 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            IN+LD ND++P F  Q + A V E +  G TV  +  +D+DIG NA   Y+I     D  
Sbjct: 1059 INILDENDNAPRFS-QIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSI----MDAS 1113

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             P                 F I+  +G ++    L+RE   RY + V A D    V    
Sbjct: 1114 LP-----------------FTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTV---- 1152

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S+  TI V   D NDN P+FS  +Y +   E   +     + ++ ATD D G+N  + Y 
Sbjct: 1153 STDVTIFVT--DINDNAPRFSRTSYYLDCPELTEIGSK--VTQVFATDPDEGSNGQVFYF 1208

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY--------RLVIRAQDGGSPSRSNTTQ 242
            I   +    F I++ +G++   + L Y+ V  +          ++ + D G PS  + T 
Sbjct: 1209 I--KSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETT 1266

Query: 243  LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY-DADEGVNAELTYTMTDKDY 301
            + INI D NDNAP+F  S +   V++NV +G  ++RV A  D D G+N+E+ Y +++ ++
Sbjct: 1267 VTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNH 1326

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
             G   L    D  +GW+  +  L  +    + + VTA D G+PP S+ AT          
Sbjct: 1327 LGKFKL----DNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENY 1382

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNG 419
                F        + E    G+ V T++A D D   +  + Y I+ GN  G F+I S   
Sbjct: 1383 HTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSST- 1441

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477
             G++T+A+ LD++  +++ +T+SA D G   R+    V +N+ D N+ +PVF +  Y  +
Sbjct: 1442 -GILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPT 1500

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            V E+AP GTTV+ ++ATD+D G NA I Y++ S  S+         FVI+P TG ITT  
Sbjct: 1501 VLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSD--------LFVIDPNTGVITTQG 1552

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
             LD ET   Y LTV A +           V I +   N+  P F  +LY   I E A  G
Sbjct: 1553 FLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKG 1612

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
            T V +V A+D D+G +G +HY +    R++G F I+  +G I  +  LDRE      LK 
Sbjct: 1613 TIVGEVFASDRDLGTDGEVHYLIFGNSRKKG-FQINKKTGQIYVSGILDREKEERVSLKV 1671

Query: 658  VAIDGGT--PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
            +A + G+        V V++ + D ND PP+F  +  +  ISE  PIGT +  + A D D
Sbjct: 1672 LAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSD 1730

Query: 716  EGPN-AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES-PRKKYE-LVIRAASP 772
              P+ +   Y I  G+++ +FS+  + G    ++    +LD E+ P      L + + +P
Sbjct: 1731 SIPSWSRFSYFIGSGNENGAFSINPQTG----QITVTAELDRETLPIYNLSVLAVDSGTP 1786

Query: 773  PLWNDVRVEILVTDVNDNAPVM 794
                   + + + D+NDN P++
Sbjct: 1787 SATGSASLLVTLEDINDNGPML 1808



 Score = 38.7 bits (86), Expect = 2.3
 Identities = 14/33 (42%), Positives = 18/33 (54%), Gaps = 1/33 (3%)

Query: 1317 CSSAPCYNGAECSD-LWDTYICDCKEGHTGKDC 1348
            C+S PC NG  C   L   + C C + HTG+ C
Sbjct: 2671 CASHPCQNGGSCEPGLHSGFTCSCPDSHTGRTC 2703


>UniRef50_UPI0000E48843 Cluster: PREDICTED: similar to Fat4; n=2;
            Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
            Fat4 - Strongylocentrotus purpuratus
          Length = 4811

 Score =  396 bits (975), Expect = e-108
 Identities = 328/1097 (29%), Positives = 512/1097 (46%), Gaps = 84/1097 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVRE-GASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +NV D ND++PVF       +  E   SSG  + T+ ATD D G N +V+Y ++ +T   
Sbjct: 2699 VNVEDTNDNAPVFTENSINTTYPEIFFSSGNVIATVSATDADDGDNGQVDYILKTMT--- 2755

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
               E            +  V  I     + +  +  D      YT  V A D+ +P    
Sbjct: 2756 ---EHFRVETINNRGWIFPVPPI-----SYIVPSPEDTSNPNTYTFSVFAVDRGTPA--- 2804

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            L   A++ + +  DN   P F+  +Y   V  +     N  + ++ A D D G+N+AI Y
Sbjct: 2805 LYGEASVIITVTQDNSYTPVFATPSYFSPVTAN--TRSNTRVLQVLAVDQDTGSNAAITY 2862

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVK--TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            +I  GN   +F +++ +G + L K  +L  +   +Y+L+++A D G+  + + T +   I
Sbjct: 2863 SISDGNGTEKFDVEADTGWI-LTKGVSLAGDVGITYQLLVKATDNGNIKKEDETTVTFLI 2921

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
             D NDNAP F    ++ S++E+V  GY +  V+A D D G+N E+TY+++  D       
Sbjct: 2922 TDSNDNAPVFDDDTYRSSIAEDVG-GY-VATVRAEDDDSGINGEITYSISGADAA----- 2974

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
              +ID  SG V   G LDRET  ++Q+ VTA D     +SATA               F+
Sbjct: 2975 LFSIDAVSGIVSLVGSLDRETSDEHQIQVTAEDRAMYSQSATAILIVTVTDVDDNPPVFL 3034

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYE--ITGGNTRGRFSITSQNGRGLITV 425
            P +Y  ++ E+ P  TPVVT+TATDAD      +E  I+GG+    F+I  + G  LI  
Sbjct: 3035 PREYRADVFENSPSATPVVTVTATDADTGTNADFEYIISGGDGTDFFTINPETG--LILT 3092

Query: 426  AQPLDFKQERR-YVLTVSATDSGGRS-DTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
               LD++  +  Y LTV+AT+      D A V + +   N + P F    Y   V E A 
Sbjct: 3093 QGNLDYETGKTTYHLTVAATNEQATMVDYAHVIVTLLGENEFYPQFTQHQYDFYVNEHAT 3152

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT---NKLLD 540
             G  V VV ATD D+G +  + Y      SN       Q F +N ++G IT    N  LD
Sbjct: 3153 DGAPVGVVLATDDDLGDDGIVNYLFIGG-SNL------QGFNVNLESGQITVAYENGRLD 3205

Query: 541  RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE--PVFKQQLYTANIMEDALVGT 598
            RET    LL+V A++ G  + +D  + E+ ++ VND    PVF  + Y A ++E    G+
Sbjct: 3206 RETADTVLLSVLAKNEGPITGADIDEAEV-IIHVNDGNDAPVFSSEQYQARVLESEPPGS 3264

Query: 599  SVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
             V+ V A D D +    + +Y +  +  E  +F ID  +G I T   LDRE+++ + L  
Sbjct: 3265 DVTVVTAADYDEIPSFRQFNYSI-LRGNEGDAFHIDARTGRITTASLLDRETLSVYFLTV 3323

Query: 658  VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
             AID G PPQ+ T +V ++++D+ND+ PVF  +     + EN P    I  +RA DPD  
Sbjct: 3324 AAIDTGNPPQTGTAVVSVELDDVNDNGPVFIGEAAEGSVFENEPPNELIMTLRATDPDSN 3383

Query: 718  PN-AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPP 773
            PN +   Y++    DS++F L    G    EL T   LD E  +  Y + I A+   SP 
Sbjct: 3384 PNPSQFTYTLLTSPDSSAFRL---VGD---ELRTTQTLDRE-VKSDYYIQIEASDGESPA 3436

Query: 774  LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILS 833
            +     + I + D NDN   ++  +I    ++  FP G  G V   D D  D    +I S
Sbjct: 3437 MSATSTIHITIADRNDNPSTLRQARIEVKMFQSMFPGGVIGSVKPIDPDTDDTFFCQITS 3496

Query: 834  GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE-IKAMMQLSVRLITEEML 892
            G+ +   + +        S   +T    +  + VS  DG ++ + +   +     T + L
Sbjct: 3497 GDLSKFSIQSNCD---LFSASHSTE--SVVDLSVSGNDGSHQSVTSSFSVVYESFTNDTL 3551

Query: 893  LNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFS 952
             NS+T+RL D +AE FL+     F   L+A +   +E + + S+ D  D+          
Sbjct: 3552 TNSLTIRLVDTSAEAFLANSYDRFKTSLSAFLG-SRETLIVLSITDHPDLD--------- 3601

Query: 953  ARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEE 1012
              + D  + +    S H     L + +  +  TL   + + +   D   C   PCLN   
Sbjct: 3602 --KVDLVLAIKKQGSQHLLHDDLVDLLEANEATLESQSDITIETIDYTACSDSPCLNSGT 3659

Query: 1013 CLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSI 1072
            C              SD V+F  +    SFTC CP  F+G  CE  +    C   G  + 
Sbjct: 3660 CSHETNINLEELITESDPVIFVGLQTSHSFTCACPAEFSGQRCE--IPTDYC---GQAT- 3713

Query: 1073 CRSGSQCVARREGGILC 1089
            C++G+ C     GG +C
Sbjct: 3714 CKNGATC-QNAIGGYIC 3729



 Score =  380 bits (936), Expect = e-103
 Identities = 293/889 (32%), Positives = 436/889 (49%), Gaps = 79/889 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +NVLD ND++PVF    Y AS+RE  +S + V T+ ATD D+  +  + Y+I  V   T 
Sbjct: 1570 VNVLDENDNAPVFTNGPYTASIRENVASNSPVKTVMATDADL--DTIIFYSI--VDGAT- 1624

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                             D+F ID  +G + TR  +DRE  A Y + ++A+D        L
Sbjct: 1625 -----------------DLFSIDSTTGQIRTRGVVDRESSAVYQLQLQASDGT------L 1661

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +ST TI +N++D+NDN P FS  TY+  V ED  V ++  +  + ATD D G N  + Y+
Sbjct: 1662 TSTTTIDINLLDENDNDPVFSLSTYSFLVPEDEMVGED--VGVVVATDPDAGLNGEVAYS 1719

Query: 191  II--GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            ++  G   +  F +D  +G   L ++LDYE  + Y + + A D GS  RS+T  + IN+ 
Sbjct: 1720 VVEEGAPGEDVFYLDPATGAFRLQQSLDYEVKQHYFMTVMATDKGSSPRSSTATVYINVE 1779

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            DVNDN P +    + E V E+V IG S+V + A D D G N EL +++     +G+    
Sbjct: 1780 DVNDNNPVYNPVDYSEEVPEDVAIGTSVVTLTATDLDSGSNGELQFSIA----SGDPSQR 1835

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPP--RSATATXXXXXXXXXXXXXX 365
             T+ P +G + T   LDRE ++ Y L V A+D   DP   RS+TA               
Sbjct: 1836 FTVYP-NGTIVTIKNLDREPESFYNLEVVASDMTLDPEDRRSSTAQVSIIVTDINDNAPR 1894

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV 425
            F      VE+AED      ++ L A D D +   + E         F+++   G   + V
Sbjct: 1895 F-TNPDSVEIAEDTRTNVIIMVLRAEDDDVERNSYVEYYLLTPGVPFAVSRVEGN--MQV 1951

Query: 426  AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
              PLD + E  Y L V ATD G   +S T  + I ITD N+ AP F   PY A++ ED P
Sbjct: 1952 TGPLDRETESSYALLVQATDKGTPPQSSTMNLTIYITDVNDNAPAFSMTPYEATLDEDTP 2011

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
            +G   L V+A+D D G+N+ I YS+ S  S  A       F I+P TG ++ N  L+ E 
Sbjct: 2012 VGLEFLKVTASDPDEGLNSIIRYSIFSGDSGRA-------FAIDPVTGVLSVNSGLNYEQ 2064

Query: 544  MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
             S Y LTV A+D G  +   +  V I+V DVNDN PVF+   Y  +IME+ L    + QV
Sbjct: 2065 RSSYTLTVRAQDQGYSTQVSSVTVTITVADVNDNAPVFEDS-YAPSIMENNLPNADIVQV 2123

Query: 604  GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
             A DAD G+NG I++ L+      G F I   SG+I+  + LD E     +L  +A D G
Sbjct: 2124 RADDADSGVNGMINFRLE--SDYNGLFTIGSTSGLIQVTEVLDYEDQNEFELIVIAEDSG 2181

Query: 664  TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
            TP   +   + + + D ND  P F SD     +SE++   T + ++ A D D    A + 
Sbjct: 2182 TPSHQTRTTMTLTVNDDNDHDPEFVSDFYRATVSEDASADTFVIQVTATDVD--ATAALR 2239

Query: 724  YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP---LWNDVRV 780
            Y +   D  + F+++   G     ++T   LD E  +  Y L +     P       VRV
Sbjct: 2240 YRL-NSDIGSKFTIDPLGG----RILTTGLLDRE-VQSSYLLTVTVDDGPSRLATTSVRV 2293

Query: 781  EILVTDVNDN----APVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSG 834
            E+L  DVNDN    +P      +   + + CF       + A D D+ D   ++Y I SG
Sbjct: 2294 EVL--DVNDNPPRFSPTSYTATLPATSQQGCF----VAAIQATDTDLEDNAAIRYSITSG 2347

Query: 835  NNANLILLNETTGSMTLSPQLNTNVP-KLATMEVSVTDGVNEIKAMMQL 882
            + +  ++  +T   +T     + N P  L     +V  G N   A +++
Sbjct: 2348 DTSKFVVDQDTGVVITAQGFTDENSPYDLQITAENVASGQNSAVASLRV 2396



 Score =  378 bits (929), Expect = e-102
 Identities = 285/904 (31%), Positives = 426/904 (47%), Gaps = 67/904 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V+D NDH+P+F  + Y A + E    G+ V ++ ATD D G NA++ Y+I   T D  
Sbjct: 302  IYVVDENDHAPMFLQESYRAGLLESIQVGSFVKSVTATDADEGINADIVYSI---TGDEY 358

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F+ID  +G + TR  LD E  A+ T+ + A+DQ     + +
Sbjct: 359  G-----------------WFQIDNGTGLVTTREKLDHETAAQVTLTITASDQGL---EPM 398

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            ++T  + ++I D ND YP F++  Y+ +V+E+    D   + ++ ATD D G N  + Y 
Sbjct: 399  ANTTILTIDIQDVNDEYPVFNQIAYSETVEENSPARD---LIQVLATDLDNGVNGDVTYT 455

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
                     FS+D  SG + +   LD E+  SY L I A DGGSPS   T  + I + D 
Sbjct: 456  FSSDQYSGMFSLDPESGLLQITVPLDREEQDSYELEILASDGGSPSLQATATVTIAVLDQ 515

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN P+FY + +  SV EN P G  +  V A D D GVN  + ++++D            
Sbjct: 516  NDNPPQFYPTEYYASVIENGPAGLFVTVVSATDLDVGVNGAVIFSLSDSS-------KFQ 568

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            ID  SG V T   LDRE ++ Y L VTA DG     + +AT              F    
Sbjct: 569  IDSYSGNVTTRESLDREQESSYTLTVTAQDGSGQAAAQSATIFVTVTDTLDNPLEFELNP 628

Query: 371  YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
            Y  +L E+ P  T V T+ AT  D +  + Y I  G+  G F I   +G    T++   +
Sbjct: 629  YRFQLEENRPNRTEVGTVLATSMDLNVEITYVIVNGDPNGLFVIDFYSGVIKTTLSIDRE 688

Query: 431  FKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
              +   + LTV A D G ++   +V+I I D N+ APVF        V E+  +G     
Sbjct: 689  AHESASFRLTVLAVD-GSQNGQTVVEIEILDINDNAPVFALPEDQVDVVENWAVGNKFYA 747

Query: 491  VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550
               TD+D   N  I Y LS         + D +F IN  +G +  NK L       Y L 
Sbjct: 748  AQVTDADSPPNNVILYDLS--------VNFDDRFGINHTSGVLFLNKDLQNYPEKEYNLQ 799

Query: 551  VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA-NIMEDALVGTSVSQVGATDAD 609
            + A D G P LS + ++ ++V DVN+N PVF   + T   + E   V + V    ATDAD
Sbjct: 800  IQATDYGTPPLSSSMNLLVTVRDVNNNAPVFVDSINTTLRLTESIPVNSIVIHALATDAD 859

Query: 610  VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669
             G NG I Y +   + +  SF I P  G++   +ALDRE V  +DL   A DGG P  +S
Sbjct: 860  QGTNGLISYRITSGNTD--SFGIFP-DGMVYVKRALDREQVDQYDLTIEATDGGVPSMTS 916

Query: 670  TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729
            T+++ I + D ND+ P F++    FY+SE   IG  +G I A D D G N  + YS    
Sbjct: 917  TLMLEIIVLDENDNRPFFDNATYNFYLSEEDDIGAAVGTIHAVDNDVGGNGELTYSFTA- 975

Query: 730  DDSNSFSLETRQGSDKAELVTMVDLDYES-----PRKKYELVIR---AASPPLWNDVRVE 781
             +   F+L +  G+    + + V LD ES         + + +R   +  P L +   V 
Sbjct: 976  -NHTLFTLNSVTGA----ITSKVSLDRESLVEAGQPTTFSIRVRVHDSGQPQLQDHADVN 1030

Query: 782  ILVTDVNDNAPVM--KDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNNA 837
            I V D+ND+ PV   + +Q   +       +    RV A D DV D   + Y I+SGN  
Sbjct: 1031 IHVVDINDSPPVFNRESYQASVSELAQNETL--IIRVSATDDDVGDNSYILYSIVSGNEE 1088

Query: 838  NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEEMLLNSI 896
                ++   G + L   L+  V +   + V   D G+   ++ +++ + ++ E     S 
Sbjct: 1089 KRFHIDHVHGQIVLIAPLDREVTEGYVLRVKARDGGIVPQESFVEVEITVLDENDHRPSF 1148

Query: 897  TVRL 900
            +V L
Sbjct: 1149 SVDL 1152



 Score =  338 bits (831), Expect = 1e-90
 Identities = 277/906 (30%), Positives = 427/906 (47%), Gaps = 85/906 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + + D ND+SP+F    Y A+V E +++GT+V+ L ATD D G N ++ Y ++       
Sbjct: 80  VTITDVNDNSPIFTQTTYFATVNESSAAGTSVVHLNATDIDQGSNGDIVYRLK------- 132

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSDR 129
                          + D F +D  +G +     L    VA  Y   V ATD+ SP    
Sbjct: 133 -------------NELTDNFALDPDTGWITLLRQLPY--VANGYLFEVTATDKGSPSQ-- 175

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV---IAKIKATDADVGANSA 186
            SS+A ++V + D+ND+ P        +      S+++  +   +  +KA D D   N  
Sbjct: 176 -SSSAFVNVMVEDENDHSPVIEVLIPEIEASGVASISETMLPGPLFNLKAIDEDREENGR 234

Query: 187 IRYAIIGGNTQMQFSIDSLS---GDVSLV------KTLDYEQVRSYRLVIRAQDGGSPSR 237
           +  +I  GN +  FS  S+S   GDV  +        +D E + SY L   A+D G+P R
Sbjct: 235 VSMSIHSGNDRNDFSGTSISLPTGDVFFLLRVSPSANIDREIIASYNLTFAAEDMGTPPR 294

Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297
                ++I + D ND+AP F    ++  + E++ +G  +  V A DADEG+NA++ Y++T
Sbjct: 295 RTYRSIIIYVVDENDHAPMFLQESYRAGLLESIQVGSFVKSVTATDADEGINADIVYSIT 354

Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357
             +Y         ID  +G V T  +LD ET A+  L +TA+D G  P + T        
Sbjct: 355 GDEYGW-----FQIDNGTGLVTTREKLDHETAAQVTLTITASDQGLEPMANTTILTIDIQ 409

Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSIT 415
                   F    Y  E  E+  P   ++ + ATD D   +  + Y  +     G FS+ 
Sbjct: 410 DVNDEYPVFNQIAYS-ETVEENSPARDLIQVLATDLDNGVNGDVTYTFSSDQYSGMFSLD 468

Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAP 473
            ++  GL+ +  PLD +++  Y L + A+D G  S   TA V I + D N+  P F    
Sbjct: 469 PES--GLLQITVPLDREEQDSYELEILASDGGSPSLQATATVTIAVLDQNDNPPQFYPTE 526

Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
           Y ASV E+ P G  V VVSATD DVG+N  + +SLS             +F I+  +G +
Sbjct: 527 YYASVIENGPAGLFVTVVSATDLDVGVNGAVIFSLSD----------SSKFQIDSYSGNV 576

Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593
           TT + LDRE  S Y LTVTA+DG   + + +  + ++V D  DN   F+   Y   + E+
Sbjct: 577 TTRESLDREQESSYTLTVTAQDGSGQAAAQSATIFVTVTDTLDNPLEFELNPYRFQLEEN 636

Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES--VA 651
               T V  V AT  D  LN  I Y +   D   G FVID  SGVI+T  ++DRE+   A
Sbjct: 637 RPNRTEVGTVLATSMD--LNVEITYVIVNGD-PNGLFVIDFYSGVIKTTLSIDREAHESA 693

Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711
           +  L  +A+DG    Q+   +V I+I DIND+ PVF        + EN  +G      + 
Sbjct: 694 SFRLTVLAVDGS---QNGQTVVEIEILDINDNAPVFALPEDQVDVVENWAVGNKFYAAQV 750

Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES-PRKKYELVIRA- 769
            D D  PN V+ Y +       S + + R G +    V  ++ D ++ P K+Y L I+A 
Sbjct: 751 TDADSPPNNVILYDL-------SVNFDDRFGINHTSGVLFLNKDLQNYPEKEYNLQIQAT 803

Query: 770 --ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDAD--VT 824
              +PPL + + + + V DVN+NAPV  D         +  PV        A DAD    
Sbjct: 804 DYGTPPLSSSMNLLVTVRDVNNNAPVFVDSINTTLRLTESIPVNSIVIHALATDADQGTN 863

Query: 825 DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLS 883
             + YRI SGN  +  +  +  G + +   L+        + +  TD GV  + + + L 
Sbjct: 864 GLISYRITSGNTDSFGIFPD--GMVYVKRALDREQVDQYDLTIEATDGGVPSMTSTLMLE 921

Query: 884 VRLITE 889
           + ++ E
Sbjct: 922 IIVLDE 927



 Score =  327 bits (804), Expect = 2e-87
 Identities = 266/897 (29%), Positives = 419/897 (46%), Gaps = 79/897 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I++ D ND  PVF    Y  +V E + +   +  L ATD D G N +V YT    ++D  
Sbjct: 406  IDIQDVNDEYPVFNQIAYSETVEENSPARDLIQVL-ATDLDNGVNGDVTYTF---SSDQY 461

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +                 +F +D  SG L     LDRE+   Y + + A+D  SP    L
Sbjct: 462  S----------------GMFSLDPESGLLQITVPLDREEQDSYELEILASDGGSP---SL 502

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             +TAT+ + ++D NDN PQF    Y  SV E+        +  + ATD DVG N A+ ++
Sbjct: 503  QATATVTIAVLDQNDNPPQFYPTEYYASVIENGPA--GLFVTVVSATDLDVGVNGAVIFS 560

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            +   +   +F IDS SG+V+  ++LD EQ  SY L + AQDG   + + +  + + + D 
Sbjct: 561  L---SDSSKFQIDSYSGNVTTRESLDREQESSYTLTVTAQDGSGQAAAQSATIFVTVTDT 617

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
             DN   F  + ++  + EN P    +  V A   D  +N E+TY + + D  G       
Sbjct: 618  LDNPLEFELNPYRFQLEENRPNRTEVGTVLATSMD--LNVEITYVIVNGDPNG----LFV 671

Query: 311  IDPRSGWVYTSGQLDRET--QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
            ID  SG + T+  +DRE    A ++L V A DG       T                 +P
Sbjct: 672  IDFYSGVIKTTLSIDREAHESASFRLTVLAVDGSQ--NGQTVVEIEILDINDNAPVFALP 729

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
             + +V++ E+   G        TDAD   +N + Y+++  N   RF I   +  G++ + 
Sbjct: 730  -EDQVDVVENWAVGNKFYAAQVTDADSPPNNVILYDLS-VNFDDRFGINHTS--GVLFLN 785

Query: 427  QPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVF-ENAPYTASVFEDAP 483
            + L    E+ Y L + ATD G    S +  + + + D NN APVF ++   T  + E  P
Sbjct: 786  KDLQNYPEKEYNLQIQATDYGTPPLSSSMNLLVTVRDVNNNAPVFVDSINTTLRLTESIP 845

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
            + + V+   ATD+D G N  I+Y ++S         +   F I P  G +   + LDRE 
Sbjct: 846  VNSIVIHALATDADQGTNGLISYRITS--------GNTDSFGIFPD-GMVYVKRALDREQ 896

Query: 544  MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
            +  Y LT+ A DGGVPS++ T  +EI V+D NDN P F    Y   + E+  +G +V  +
Sbjct: 897  VDQYDLTIEATDGGVPSMTSTLMLEIIVLDENDNRPFFDNATYNFYLSEEDDIGAAVGTI 956

Query: 604  GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV------ATHDLKA 657
             A D DVG NG + Y           F ++  +G I +  +LDRES+       T  ++ 
Sbjct: 957  HAVDNDVGGNGELTYSF---TANHTLFTLNSVTGAITSKVSLDRESLVEAGQPTTFSIRV 1013

Query: 658  VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
               D G P       V+I + DINDSPPVF  +     +SE +   T I  + A D D G
Sbjct: 1014 RVHDSGQPQLQDHADVNIHVVDINDSPPVFNRESYQASVSELAQNETLIIRVSATDDDVG 1073

Query: 718  PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPL 774
             N+ + YSI  G++   F ++   G    ++V +  LD E   + Y L ++A      P 
Sbjct: 1074 DNSYILYSIVSGNEEKRFHIDHVHG----QIVLIAPLDRE-VTEGYVLRVKARDGGIVPQ 1128

Query: 775  WNDVRVEILVTDVNDNAPVMK-DFQIIFNNYKDCFPVG-PFGRVPAYDADVTD--KLQYR 830
             + V VEI V D ND+ P    D Q       +C  +G   G V A D D+    ++ Y 
Sbjct: 1129 ESFVEVEITVLDENDHRPSFSVDLQREI-EVTECLQIGDTIGGVQATDMDINSNGQISYT 1187

Query: 831  ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN-EIKAMMQLSVRL 886
            I  GN   +  +N  +G + L+  L+       ++ ++  DG +  ++A++ + + +
Sbjct: 1188 ITGGNLDGVFGVNANSGEVYLTGYLDHEATSQYSLNITARDGGSPSLQAVVSMVINI 1244



 Score =  326 bits (801), Expect = 5e-87
 Identities = 263/809 (32%), Positives = 393/809 (48%), Gaps = 78/809 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I+V+D ND  PVF  + Y+ASV E A + T ++ + ATD D+G N+ + Y+I  V+    
Sbjct: 1031 IHVVDINDSPPVFNRESYQASVSELAQNETLIIRVSATDDDVGDNSYILYSI--VSG--- 1085

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N E                F ID   G ++  A LDRE    Y + VKA D      +  
Sbjct: 1086 NEEKR--------------FHIDHVHGQIVLIAPLDREVTEGYVLRVKARDGGIVPQE-- 1129

Query: 131  SSTATIHVNIIDDNDNYPQFS-EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             S   + + ++D+ND+ P FS +    + V E + + D   I  ++ATD D+ +N  I Y
Sbjct: 1130 -SFVEVEITVLDENDHRPSFSVDLQREIEVTECLQIGDT--IGGVQATDMDINSNGQISY 1186

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             I GGN    F +++ SG+V L   LD+E    Y L I A+DGGSPS      ++INIRD
Sbjct: 1187 TITGGNLDGVFGVNANSGEVYLTGYLDHEATSQYSLNITARDGGSPSLQAVVSMVINIRD 1246

Query: 250  VNDNAPRF-YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
             NDN+P F Y  +    + E  P G+ +VRV A D+D GVN E+ ++++ +  +G+    
Sbjct: 1247 CNDNSPIFAYVGV--PEIDEEKPEGFEVVRVSASDSDSGVNGEVRFSISSQRPSGDF--- 1301

Query: 309  ITIDPRSGWVYTSGQLDRETQA----KYQLLVTATDGGDP---PRSATATXXXXXXXXXX 361
              IDP SGW+ T+ ++DRE++     ++ L V  TD   P    R+AT            
Sbjct: 1302 FAIDPESGWITTNSRIDRESEIMATDQFILTVHGTDLAVPVESRRTATVDVVIFVRDIND 1361

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNG 419
                F   Q    ++      T V T+ A D D   + ++ Y +       R  + +   
Sbjct: 1362 NAPRF-TSQQAAAISRSTSANTRVTTVHADDPDTGVNGQVTYTLISTGVPFRLDLIT--- 1417

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSGG----RSDTAMVQINITDANNYAPVFENAPYT 475
             G +T+ QP+       Y L + A D+G     +S    + I I+D  +    +    YT
Sbjct: 1418 -GELTLTQPIP-SSANIYSLDIRADDAGSNPQQQSTPFSLAIIISDGQSSILNYVQNTYT 1475

Query: 476  ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ--TGAI 533
             SV E+ P GT ++ V A  SD G +A + Y +S+  +       D+  +I      G I
Sbjct: 1476 GSVRENQPAGTEIVTVVAQYSD-GRSATVRYYVSAVTAGGV----DKGSLIRASVTNGII 1530

Query: 534  TTNKLLDRETMSG---YLLTVTARDGGVPSLSDTT-DVEISVVDVNDNEPVFKQQLYTAN 589
             T+ +LDRE + G    + TV A D    S   T+  V ++V+D NDN PVF    YTA+
Sbjct: 1531 RTDAVLDREDLGGGSSLVATVYAVDTSSSSSHVTSVQVTVNVLDENDNAPVFTNGPYTAS 1590

Query: 590  IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES 649
            I E+    + V  V ATDAD  L+  I Y +   D     F ID  +G IRT   +DRES
Sbjct: 1591 IRENVASNSPVKTVMATDAD--LDTIIFYSI--VDGATDLFSIDSTTGQIRTRGVVDRES 1646

Query: 650  VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
             A + L+  A DG     +ST  + I + D ND+ PVF     +F + E+  +G  +G +
Sbjct: 1647 SAVYQLQLQASDG---TLTSTTTIDINLLDENDNDPVFSLSTYSFLVPEDEMVGEDVGVV 1703

Query: 710  RAHDPDEGPNAVVHYSI--KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
             A DPD G N  V YS+  +G    + F L+   G+ + +      LDYE  ++ Y + +
Sbjct: 1704 VATDPDAGLNGEVAYSVVEEGAPGEDVFYLDPATGAFRLQ----QSLDYE-VKQHYFMTV 1758

Query: 768  RA---ASPPLWNDVRVEILVTDVNDNAPV 793
             A    S P  +   V I V DVNDN PV
Sbjct: 1759 MATDKGSSPRSSTATVYINVEDVNDNNPV 1787



 Score =  323 bits (794), Expect = 4e-86
 Identities = 253/815 (31%), Positives = 392/815 (48%), Gaps = 82/815 (10%)

Query: 7    IHQQINVLDCNDHSPVFEMQ-QYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELV 65
            +  +I VLD NDH P F +  Q E  V E    G T+  ++ATD DI  N ++ YTI   
Sbjct: 1132 VEVEITVLDENDHRPSFSVDLQREIEVTECLQIGDTIGGVQATDMDINSNGQISYTI--- 1188

Query: 66   TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125
            T   L+                 VF ++  SG +     LD E  ++Y++ + A D  SP
Sbjct: 1189 TGGNLD----------------GVFGVNANSGEVYLTGYLDHEATSQYSLNITARDGGSP 1232

Query: 126  VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
                L +  ++ +NI D NDN P F+   Y    + D    +   + ++ A+D+D G N 
Sbjct: 1233 ---SLQAVVSMVINIRDCNDNSPIFA---YVGVPEIDEEKPEGFEVVRVSASDSDSGVNG 1286

Query: 186  AIRYAIIGGNTQMQ-FSIDSLSGDVSLVKTLDYEQ----VRSYRLVIRAQDGGSP---SR 237
             +R++I         F+ID  SG ++    +D E        + L +   D   P    R
Sbjct: 1287 EVRFSISSQRPSGDFFAIDPESGWITTNSRIDRESEIMATDQFILTVHGTDLAVPVESRR 1346

Query: 238  SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297
            + T  ++I +RD+NDNAPRF TS    ++S +      +  V A D D GVN ++TYT+ 
Sbjct: 1347 TATVDVVIFVRDINDNAPRF-TSQQAAAISRSTSANTRVTTVHADDPDTGVNGQVTYTLI 1405

Query: 298  DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXX 355
                TG   +P  +D  +G +  +  +       Y L + A D G  P  +S   +    
Sbjct: 1406 S---TG---VPFRLDLITGELTLTQPIPSSANI-YSLDIRADDAGSNPQQQSTPFSLAII 1458

Query: 356  XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD-EDNRLHYEIT----GGNTRG 410
                      ++   Y   + E++P GT +VT+ A  +D     + Y ++    GG  +G
Sbjct: 1459 ISDGQSSILNYVQNTYTGSVRENQPAGTEIVTVVAQYSDGRSATVRYYVSAVTAGGVDKG 1518

Query: 411  RFSITSQNGRGLITVAQPLDFKQ---ERRYVLTVSATDSGGRSD---TAMVQINITDANN 464
               I +    G+I     LD +        V TV A D+   S    +  V +N+ D N+
Sbjct: 1519 SL-IRASVTNGIIRTDAVLDREDLGGGSSLVATVYAVDTSSSSSHVTSVQVTVNVLDEND 1577

Query: 465  YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524
             APVF N PYTAS+ E+    + V  V ATD+D  ++  I YS+        V      F
Sbjct: 1578 NAPVFTNGPYTASIRENVASNSPVKTVMATDAD--LDTIIFYSI--------VDGATDLF 1627

Query: 525  VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584
             I+  TG I T  ++DRE+ + Y L + A DG   +L+ TT ++I+++D NDN+PVF   
Sbjct: 1628 SIDSTTGQIRTRGVVDRESSAVYQLQLQASDG---TLTSTTTIDINLLDENDNDPVFSLS 1684

Query: 585  LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNK 643
             Y+  + ED +VG  V  V ATD D GLNG + Y +  +    E  F +DPA+G  R  +
Sbjct: 1685 TYSFLVPEDEMVGEDVGVVVATDPDAGLNGEVAYSVVEEGAPGEDVFYLDPATGAFRLQQ 1744

Query: 644  ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703
            +LD E    + +  +A D G+ P+SST  V+I +ED+ND+ PV+     +  + E+  IG
Sbjct: 1745 SLDYEVKQHYFMTVMATDKGSSPRSSTATVYINVEDVNDNNPVYNPVDYSEEVPEDVAIG 1804

Query: 704  TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY 763
            T++  + A D D G N  + +SI  GD S  F++          +VT+ +LD E P   Y
Sbjct: 1805 TSVVTLTATDLDSGSNGELQFSIASGDPSQRFTV-----YPNGTIVTIKNLDRE-PESFY 1858

Query: 764  ELVIRAASPPL------WNDVRVEILVTDVNDNAP 792
             L + A+   L       +  +V I+VTD+NDNAP
Sbjct: 1859 NLEVVASDMTLDPEDRRSSTAQVSIIVTDINDNAP 1893



 Score =  321 bits (788), Expect = 2e-85
 Identities = 274/892 (30%), Positives = 414/892 (46%), Gaps = 70/892 (7%)

Query: 2    SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
            S+   +   IN+ DCND+SP+F        + E    G  V+ + A+D D G N EV ++
Sbjct: 1233 SLQAVVSMVINIRDCNDNSPIFAYVGVP-EIDEEKPEGFEVVRVSASDSDSGVNGEVRFS 1291

Query: 62   IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREK----VARYTVLV 117
            I      +  P               D F ID  SG + T + +DRE       ++ + V
Sbjct: 1292 IS-----SQRPSG-------------DFFAIDPESGWITTNSRIDRESEIMATDQFILTV 1333

Query: 118  KATDQASPVSDRLSSTATIHVNIIDDNDNYPQF-SEKTYTVSVDEDISVTDNPVIAKIKA 176
              TD A PV  R ++T  + + + D NDN P+F S++   +S     S + N  +  + A
Sbjct: 1334 HGTDLAVPVESRRTATVDVVIFVRDINDNAPRFTSQQAAAIS----RSTSANTRVTTVHA 1389

Query: 177  TDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS 236
             D D G N  + Y +I  +T + F +D ++G+++L + +       Y L IRA D GS  
Sbjct: 1390 DDPDTGVNGQVTYTLI--STGVPFRLDLITGELTLTQPIP-SSANIYSLDIRADDAGSNP 1446

Query: 237  RSNTT--QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294
            +  +T   L I I D   +   +  + +  SV EN P G  IV V A  +D G +A + Y
Sbjct: 1447 QQQSTPFSLAIIISDGQSSILNYVQNTYTGSVRENQPAGTEIVTVVAQYSD-GRSATVRY 1505

Query: 295  TMTDKDYTGNVDLP--ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352
             ++     G VD    I     +G + T   LDRE       LV      D   S++   
Sbjct: 1506 YVSAVT-AGGVDKGSLIRASVTNGIIRTDAVLDREDLGGGSSLVATVYAVDTSSSSSHVT 1564

Query: 353  XXXXX----XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT 408
                             F  G Y   + E+    +PV T+ ATDAD D  + Y I  G T
Sbjct: 1565 SVQVTVNVLDENDNAPVFTNGPYTASIRENVASNSPVKTVMATDADLDTIIFYSIVDGAT 1624

Query: 409  RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468
               FSI S  G+  I     +D +    Y L + A+D G  + T  + IN+ D N+  PV
Sbjct: 1625 -DLFSIDSTTGQ--IRTRGVVDRESSAVYQLQLQASD-GTLTSTTTIDINLLDENDNDPV 1680

Query: 469  FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528
            F  + Y+  V ED  +G  V VV ATD D G+N ++ YS+  E      A  +  F ++P
Sbjct: 1681 FSLSTYSFLVPEDEMVGEDVGVVVATDPDAGLNGEVAYSVVEE-----GAPGEDVFYLDP 1735

Query: 529  QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588
             TGA    + LD E    Y +TV A D G    S T  V I+V DVNDN PV+    Y+ 
Sbjct: 1736 ATGAFRLQQSLDYEVKQHYFMTVMATDKGSSPRSSTATVYINVEDVNDNNPVYNPVDYSE 1795

Query: 589  NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648
             + ED  +GTSV  + ATD D G NG + + +   D  +  F + P +G I T K LDRE
Sbjct: 1796 EVPEDVAIGTSVVTLTATDLDSGSNGELQFSIASGDPSQ-RFTVYP-NGTIVTIKNLDRE 1853

Query: 649  SVATHDLKAVAIDGGTPPQ---SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
              + ++L+ VA D    P+   SST  V I + DIND+ P F +   +  I+E++     
Sbjct: 1854 PESFYNLEVVASDMTLDPEDRRSSTAQVSIIVTDINDNAPRFTNPD-SVEIAEDTRTNVI 1912

Query: 706  IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765
            I  +RA D D   N+ V Y +        F++   +G+   ++   +D + ES    Y L
Sbjct: 1913 IMVLRAEDDDVERNSYVEYYLL--TPGVPFAVSRVEGN--MQVTGPLDRETES---SYAL 1965

Query: 766  VIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDA 821
            +++A    +PP  + + + I +TDVNDNAP            +D  PVG  F +V A D 
Sbjct: 1966 LVQATDKGTPPQSSTMNLTIYITDVNDNAPAFSMTPYEATLDEDT-PVGLEFLKVTASDP 2024

Query: 822  D--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            D  +   ++Y I SG++     ++  TG ++++  LN       T+ V   D
Sbjct: 2025 DEGLNSIIRYSIFSGDSGRAFAIDPVTGVLSVNSGLNYEQRSSYTLTVRAQD 2076



 Score =  310 bits (760), Expect = 5e-82
 Identities = 243/805 (30%), Positives = 385/805 (47%), Gaps = 47/805 (5%)

Query: 98  ALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTV 157
           +L+T + LDRE    Y + + ATD +S      +    ++V I D NDN P F++ TY  
Sbjct: 43  SLVTNSLLDRETEDFYILNISATDNSSTPR---TGYLIVNVTITDVNDNSPIFTQTTYFA 99

Query: 158 SVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDY 217
           +V+E  S      +  + ATD D G+N  I Y +    T   F++D  +G ++L++ L Y
Sbjct: 100 TVNE--SSAAGTSVVHLNATDIDQGSNGDIVYRLKNELTD-NFALDPDTGWITLLRQLPY 156

Query: 218 EQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ------ESVSENVP 271
                Y   + A D GSPS+S++  + + + D ND++P     + +       S+SE + 
Sbjct: 157 -VANGYLFEVTATDKGSPSQSSSAFVNVMVEDENDHSPVIEVLIPEIEASGVASISETML 215

Query: 272 IGYSIVRVQAYDADEGVNAELTYTM---TDK-DYTG-NVDLPITIDPRSGWVYTSGQLDR 326
            G  +  ++A D D   N  ++ ++    D+ D++G ++ LP         V  S  +DR
Sbjct: 216 PG-PLFNLKAIDEDREENGRVSMSIHSGNDRNDFSGTSISLPTGDVFFLLRVSPSANIDR 274

Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386
           E  A Y L   A D G PPR    +              F+   Y   L E    G+ V 
Sbjct: 275 EIIASYNLTFAAEDMGTPPRRTYRSIIIYVVDENDHAPMFLQESYRAGLLESIQVGSFVK 334

Query: 387 TLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444
           ++TATDADE  +  + Y IT G+  G F I   NG GL+T  + LD +   +  LT++A+
Sbjct: 335 SVTATDADEGINADIVYSIT-GDEYGWFQI--DNGTGLVTTREKLDHETAAQVTLTITAS 391

Query: 445 DSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502
           D G    ++T ++ I+I D N+  PVF    Y+ +V E++P    ++ V ATD D G+N 
Sbjct: 392 DQGLEPMANTTILTIDIQDVNDEYPVFNQIAYSETVEENSP-ARDLIQVLATDLDNGVNG 450

Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
            +TY+ SS+        +   F ++P++G +     LDRE    Y L + A DGG PSL 
Sbjct: 451 DVTYTFSSD-------QYSGMFSLDPESGLLQITVPLDREEQDSYELEILASDGGSPSLQ 503

Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP 622
            T  V I+V+D NDN P F    Y A+++E+   G  V+ V ATD DVG+NG + + L  
Sbjct: 504 ATATVTIAVLDQNDNPPQFYPTEYYASVIENGPAGLFVTVVSATDLDVGVNGAVIFSLS- 562

Query: 623 KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND 682
              +   F ID  SG + T ++LDRE  +++ L   A DG     + +  + + + D  D
Sbjct: 563 ---DSSKFQIDSYSGNVTTRESLDREQESSYTLTVTAQDGSGQAAAQSATIFVTVTDTLD 619

Query: 683 SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
           +P  FE +   F + EN P  T +G + A   D   N  + Y I  GD +  F ++   G
Sbjct: 620 NPLEFELNPYRFQLEENRPNRTEVGTVLATSMD--LNVEITYVIVNGDPNGLFVIDFYSG 677

Query: 743 SDKAELVTMVDLDYESPRK-KYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801
             K    T + +D E+     + L + A          VEI + D+NDNAPV    +   
Sbjct: 678 VIK----TTLSIDREAHESASFRLTVLAVDGSQNGQTVVEIEILDINDNAPVFALPEDQV 733

Query: 802 NNYKDCFPVGPFGRVPAYDAD-VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVP 860
           +  ++      F      DAD   + +    LS N  +   +N T+G + L+  L     
Sbjct: 734 DVVENWAVGNKFYAAQVTDADSPPNNVILYDLSVNFDDRFGINHTSGVLFLNKDLQNYPE 793

Query: 861 KLATMEVSVTD-GVNEIKAMMQLSV 884
           K   +++  TD G   + + M L V
Sbjct: 794 KEYNLQIQATDYGTPPLSSSMNLLV 818



 Score =  306 bits (751), Expect = 6e-81
 Identities = 262/891 (29%), Positives = 404/891 (45%), Gaps = 67/891 (7%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ VLD ND+ P F    Y A++   +  G  V  ++ATD D+  NA + Y+I   + DT
Sbjct: 2292 RVEVLDVNDNPPRFSPTSYTATLPATSQQGCFVAAIQATDTDLEDNAAIRYSI--TSGDT 2349

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                                F +D  +G ++T      E  + Y + + A + AS  +  
Sbjct: 2350 SK------------------FVVDQDTGVVITAQGFTDEN-SPYDLQITAENVASGQNSA 2390

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            ++S     + +I    ++P     T+  S     S  +N +      T   +G    + Y
Sbjct: 2391 VAS-----LRVIFSTASFPDI---TFPFSGTSS-SYGENVMTGMTVTTVTAIGI---VTY 2438

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            +I GGN    F + S SG+VS++K LDYE+ +S+ L I A D  +   S+  +L +++ D
Sbjct: 2439 SIAGGNHGEHFGVGSQSGEVSIIKELDYEESKSFSLWIAATDTANTQLSDFVELQVSVLD 2498

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            VNDNAP F  S++  SV E       +V V A D D   N +++Y +T     GN +   
Sbjct: 2499 VNDNAPLFDQSVYFTSVVEEQSGQVQVVSVSATDEDSLSNGDVSYAIT----LGNTNNAF 2554

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             I   SG + T+  LDRET A Y L V ATDGG+P +S +A               F   
Sbjct: 2555 DIS-SSGVITTTQPLDRETVASYILTVEATDGGNPSQSGSAIVVVTVTDINDNRMSFTK- 2612

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
             Y+  + ED PPGT VVTL  TD DE+N   + I  G     F+I    G   IT+   L
Sbjct: 2613 MYDATIPEDAPPGTHVVTLHTTDPDENNLSQFSIEAGGQSSLFAINPITGE--ITLNSSL 2670

Query: 430  DFKQERRYVLTVSATDSGGRSDT-AMVQINITDANNYAPVF-ENAPYTASVFEDAPIGTT 487
            DF+ E  + L V + D     +    V +N+ D N+ APVF EN+  T         G  
Sbjct: 2671 DFEDEAVHYLLVKSFDPDSSHEVQTQVLVNVEDTNDNAPVFTENSINTTYPEIFFSSGNV 2730

Query: 488  VLVVSATDSDVGINAQITYSLSSEISN---EAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            +  VSATD+D G N Q+ Y L +   +   E + +    F + P +  + + +  D    
Sbjct: 2731 IATVSATDADDGDNGQVDYILKTMTEHFRVETINNRGWIFPVPPISYIVPSPE--DTSNP 2788

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
            + Y  +V A D G P+L     V I+V   N   PVF    Y + +  +    T V QV 
Sbjct: 2789 NTYTFSVFAVDRGTPALYGEASVIITVTQDNSYTPVFATPSYFSPVTANTRSNTRVLQVL 2848

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT-NKALDRESVATHDLKAVAIDGG 663
            A D D G N  I Y +   +  E  F ++  +G I T   +L  +   T+ L   A D G
Sbjct: 2849 AVDQDTGSNAAITYSISDGNGTE-KFDVEADTGWILTKGVSLAGDVGITYQLLVKATDNG 2907

Query: 664  TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
               +     V   I D ND+ PVF+ D     I+E+  +G  +  +RA D D G N  + 
Sbjct: 2908 NIKKEDETTVTFLITDSNDNAPVFDDDTYRSSIAED--VGGYVATVRAEDDDSGINGEIT 2965

Query: 724  YSIKGGDDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRAASPPLWNDVRVEI 782
            YSI G  D+  FS++   G     +V++V  LD E+   ++++ + A    +++     I
Sbjct: 2966 YSISGA-DAALFSIDAVSG-----IVSLVGSLDRET-SDEHQIQVTAEDRAMYSQSATAI 3018

Query: 783  L---VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNA 837
            L   VTDV+DN PV    +   + +++     P   V A DAD       +Y I  G+  
Sbjct: 3019 LIVTVTDVDDNPPVFLPREYRADVFENSPSATPVVTVTATDADTGTNADFEYIISGGDGT 3078

Query: 838  NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLIT 888
            +   +N  TG +     L+    K  T  ++V    NE   M+  +  ++T
Sbjct: 3079 DFFTINPETGLILTQGNLDYETGK-TTYHLTVA-ATNEQATMVDYAHVIVT 3127



 Score =  303 bits (743), Expect = 6e-80
 Identities = 264/865 (30%), Positives = 390/865 (45%), Gaps = 73/865 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT-IELVTADT 69
            I V D ND++P F  QQ  A++    S+ T V T+ A D D G N +V YT I       
Sbjct: 1354 IFVRDINDNAPRFTSQQ-AAAISRSTSANTRVTTVHADDPDTGVNGQVTYTLISTGVPFR 1412

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            L+                +++ +D R+       S  +++   +++ +  +D  S + + 
Sbjct: 1413 LDLITGELTLTQPIPSSANIYSLDIRAD---DAGSNPQQQSTPFSLAIIISDGQSSILNY 1469

Query: 130  LSSTATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            + +T T  V      +N P  +E  T      +  S T    ++ + A   D G  S IR
Sbjct: 1470 VQNTYTGSV-----RENQPAGTEIVTVVAQYSDGRSATVRYYVSAVTAGGVDKG--SLIR 1522

Query: 189  YAIIGG--NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
             ++  G   T      + L G  SLV T           V       S S   + Q+ +N
Sbjct: 1523 ASVTNGIIRTDAVLDREDLGGGSSLVAT-----------VYAVDTSSSSSHVTSVQVTVN 1571

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            + D NDNAP F    +  S+ ENV     +  V A DAD  ++  + Y++ D    G  D
Sbjct: 1572 VLDENDNAPVFTNGPYTASIRENVASNSPVKTVMATDAD--LDTIIFYSIVD----GATD 1625

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
            L  +ID  +G + T G +DRE+ A YQL + A+DG     ++T T              F
Sbjct: 1626 L-FSIDSTTGQIRTRGVVDRESSAVYQLQLQASDG---TLTSTTTIDINLLDENDNDPVF 1681

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLIT 424
                Y   + EDE  G  V  + ATD D   +  + Y +      G          G   
Sbjct: 1682 SLSTYSFLVPEDEMVGEDVGVVVATDPDAGLNGEVAYSVVEEGAPGEDVFYLDPATGAFR 1741

Query: 425  VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
            + Q LD++ ++ Y +TV ATD G   RS TA V IN+ D N+  PV+    Y+  V ED 
Sbjct: 1742 LQQSLDYEVKQHYFMTVMATDKGSSPRSSTATVYINVEDVNDNNPVYNPVDYSEEVPEDV 1801

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
             IGT+V+ ++ATD D G N ++ +S++S           Q+F + P  G I T K LDRE
Sbjct: 1802 AIGTSVVTLTATDLDSGSNGELQFSIAS-------GDPSQRFTVYP-NGTIVTIKNLDRE 1853

Query: 543  TMSGYLLTVTARDGGV---PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
              S Y L V A D  +      S T  V I V D+NDN P F     +  I ED      
Sbjct: 1854 PESFYNLEVVASDMTLDPEDRRSSTAQVSIIVTDINDNAPRFTNP-DSVEIAEDTRTNVI 1912

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
            +  + A D DV  N  + Y L         F +    G ++    LDRE+ +++ L   A
Sbjct: 1913 IMVLRAEDDDVERNSYVEYYLLTPG---VPFAVSRVEGNMQVTGPLDRETESSYALLVQA 1969

Query: 660  IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
             D GTPPQSST+ + I I D+ND+ P F        + E++P+G    ++ A DPDEG N
Sbjct: 1970 TDKGTPPQSSTMNLTIYITDVNDNAPAFSMTPYEATLDEDTPVGLEFLKVTASDPDEGLN 2029

Query: 720  AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWN 776
            +++ YSI  GD   +F+++   G     L     L+YE  R  Y L +RA         +
Sbjct: 2030 SIIRYSIFSGDSGRAFAIDPVTG----VLSVNSGLNYEQ-RSSYTLTVRAQDQGYSTQVS 2084

Query: 777  DVRVEILVTDVNDNAPVMKDF---QIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRI 831
             V V I V DVNDNAPV +D     I+ NN     P     +V A DAD  V   + +R+
Sbjct: 2085 SVTVTITVADVNDNAPVFEDSYAPSIMENN----LPNADIVQVRADDADSGVNGMINFRL 2140

Query: 832  LSGNNANLILLNETTGSMTLSPQLN 856
             S  N  L  +  T+G + ++  L+
Sbjct: 2141 ESDYN-GLFTIGSTSGLIQVTEVLD 2164



 Score =  295 bits (723), Expect = 1e-77
 Identities = 260/889 (29%), Positives = 401/889 (45%), Gaps = 69/889 (7%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            +  Q++VLD ND++P+F+   Y  SV E  S    V+++ ATD+D   N +V Y I L  
Sbjct: 2490 VELQVSVLDVNDNAPLFDQSVYFTSVVEEQSGQVQVVSVSATDEDSLSNGDVSYAITL-- 2547

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
             +T N  D                     SG + T   LDRE VA Y + V+ATD  +P 
Sbjct: 2548 GNTNNAFDISS------------------SGVITTTQPLDRETVASYILTVEATDGGNPS 2589

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
                S +A + V + D NDN   F+ K Y  ++ ED     +  +  +  TD D   N+ 
Sbjct: 2590 Q---SGSAIVVVTVTDINDNRMSFT-KMYDATIPEDAPPGTH--VVTLHTTDPD--ENNL 2641

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
             +++I  G     F+I+ ++G+++L  +LD+E    + L++++ D  S S    TQ+L+N
Sbjct: 2642 SQFSIEAGGQSSLFAINPITGEITLNSSLDFEDEAVHYLLVKSFDPDS-SHEVQTQVLVN 2700

Query: 247  IRDVNDNAPRFYTSLFQESVSE-NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
            + D NDNAP F  +    +  E     G  I  V A DAD+G N ++ Y +        V
Sbjct: 2701 VEDTNDNAPVFTENSINTTYPEIFFSSGNVIATVSATDADDGDNGQVDYILKTMTEHFRV 2760

Query: 306  DLPITIDPRSGWVYTSGQL--------DRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357
            +   TI+ R GW++    +        D      Y   V A D G P     A+      
Sbjct: 2761 E---TINNR-GWIFPVPPISYIVPSPEDTSNPNTYTFSVFAVDRGTPALYGEASVIITVT 2816

Query: 358  XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSIT 415
                    F    Y   +  +    T V+ + A D D  +   + Y I+ GN   +F + 
Sbjct: 2817 QDNSYTPVFATPSYFSPVTANTRSNTRVLQVLAVDQDTGSNAAITYSISDGNGTEKFDVE 2876

Query: 416  SQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAP 473
            +  G  ++T    L       Y L V ATD+G   + D   V   ITD+N+ APVF++  
Sbjct: 2877 ADTG-WILTKGVSLAGDVGITYQLLVKATDNGNIKKEDETTVTFLITDSNDNAPVFDDDT 2935

Query: 474  YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
            Y +S+ ED  +G  V  V A D D GIN +ITYS+S   ++ A+      F I+  +G +
Sbjct: 2936 YRSSIAED--VGGYVATVRAEDDDSGINGEITYSISG--ADAAL------FSIDAVSGIV 2985

Query: 534  TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593
            +    LDRET   + + VTA D  + S S T  + ++V DV+DN PVF  + Y A++ E+
Sbjct: 2986 SLVGSLDRETSDEHQIQVTAEDRAMYSQSATAILIVTVTDVDDNPPVFLPREYRADVFEN 3045

Query: 594  ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT- 652
            +   T V  V ATDAD G N    Y +   D  +  F I+P +G+I T   LD E+  T 
Sbjct: 3046 SPSATPVVTVTATDADTGTNADFEYIISGGDGTD-FFTINPETGLILTQGNLDYETGKTT 3104

Query: 653  -HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711
             H   A   +  T    + VIV +  E  N+  P F      FY++E++  G  +G + A
Sbjct: 3105 YHLTVAATNEQATMVDYAHVIVTLLGE--NEFYPQFTQHQYDFYVNEHATDGAPVGVVLA 3162

Query: 712  HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771
             D D G + +V+Y   GG +   F++    G           LD E+       V+    
Sbjct: 3163 TDDDLGDDGIVNYLFIGGSNLQGFNVNLESGQITVAYEN-GRLDRETADTVLLSVLAKNE 3221

Query: 772  PPLWN-DVRVEILVTDVND--NAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--- 825
             P+   D+    ++  VND  +APV    Q      +   P      V A D D      
Sbjct: 3222 GPITGADIDEAEVIIHVNDGNDAPVFSSEQYQARVLESEPPGSDVTVVTAADYDEIPSFR 3281

Query: 826  KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN 874
            +  Y IL GN  +   ++  TG +T +  L+     +  + V+  D  N
Sbjct: 3282 QFNYSILRGNEGDAFHIDARTGRITTASLLDRETLSVYFLTVAAIDTGN 3330



 Score =  294 bits (722), Expect = 2e-77
 Identities = 240/794 (30%), Positives = 366/794 (46%), Gaps = 70/794 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND++PVFE   Y  S+ E       ++ ++A D D G N  + + +E       
Sbjct: 2090 ITVADVNDNAPVFE-DSYAPSIMENNLPNADIVQVRADDADSGVNGMINFRLE------- 2141

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                              +F I   SG +     LD E    + ++V A D  +P S + 
Sbjct: 2142 -------------SDYNGLFTIGSTSGLIQVTEVLDYEDQNEFELIVIAEDSGTP-SHQT 2187

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             +T T+ VN  DDND+ P+F    Y  +V ED S   +  + ++ ATD D  A +A+RY 
Sbjct: 2188 RTTMTLTVN--DDNDHDPEFVSDFYRATVSEDASA--DTFVIQVTATDVD--ATAALRYR 2241

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            +   +   +F+ID L G +     LD E   SY L +   DG  PSR  TT + + + DV
Sbjct: 2242 L-NSDIGSKFTIDPLGGRILTTGLLDREVQSSYLLTVTVDDG--PSRLATTSVRVEVLDV 2298

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN PRF  + +  ++      G  +  +QA D D   NA + Y++T  D +  V     
Sbjct: 2299 NDNPPRFSPTSYTATLPATSQQGCFVAAIQATDTDLEDNAAIRYSITSGDTSKFV----- 2353

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            +D  +G V T+     E  + Y L +TA +      SA A+              F    
Sbjct: 2354 VDQDTGVVITAQGFTDEN-SPYDLQITAENVASGQNSAVASLRVIFSTASFPDITFPFSG 2412

Query: 371  YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
                  E+   G  V T+TA        + Y I GGN    F + SQ+G   +++ + LD
Sbjct: 2413 TSSSYGENVMTGMTVTTVTAIGI-----VTYSIAGGNHGEHFGVGSQSGE--VSIIKELD 2465

Query: 431  FKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
            +++ + + L ++ATD+     SD   +Q+++ D N+ AP+F+ + Y  SV E+      V
Sbjct: 2466 YEESKSFSLWIAATDTANTQLSDFVELQVSVLDVNDNAPLFDQSVYFTSVVEEQSGQVQV 2525

Query: 489  LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
            + VSATD D   N  ++Y+++   +N A       F I+  +G ITT + LDRET++ Y+
Sbjct: 2526 VSVSATDEDSLSNGDVSYAITLGNTNNA-------FDIS-SSGVITTTQPLDRETVASYI 2577

Query: 549  LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
            LTV A DGG PS S +  V ++V D+NDN   F  ++Y A I EDA  GT V  +  TD 
Sbjct: 2578 LTVEATDGGNPSQSGSAIVVVTVTDINDNRMSF-TKMYDATIPEDAPPGTHVVTLHTTDP 2636

Query: 609  DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
            D   N    + ++    +   F I+P +G I  N +LD E  A H L   + D  +  + 
Sbjct: 2637 DE--NNLSQFSIE-AGGQSSLFAINPITGEITLNSSLDFEDEAVHYLLVKSFDPDSSHEV 2693

Query: 669  STVIVHIKIEDINDSPPVF-ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
             T ++ + +ED ND+ PVF E+   T Y       G  I  + A D D+G N  V Y +K
Sbjct: 2694 QTQVL-VNVEDTNDNAPVFTENSINTTYPEIFFSSGNVIATVSATDADDGDNGQVDYILK 2752

Query: 728  GGDDSNSFSLETRQGSDKAELVTMVDLDYESPR-----KKYELVIRA---ASPPLWNDVR 779
                +  F +ET         V  +     SP        Y   + A    +P L+ +  
Sbjct: 2753 --TMTEHFRVETINNRGWIFPVPPISYIVPSPEDTSNPNTYTFSVFAVDRGTPALYGEAS 2810

Query: 780  VEILVTDVNDNAPV 793
            V I VT  N   PV
Sbjct: 2811 VIITVTQDNSYTPV 2824



 Score =  285 bits (698), Expect = 2e-74
 Identities = 252/895 (28%), Positives = 415/895 (46%), Gaps = 86/895 (9%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I VLD ND+ P F+   Y   + E    G  V T+ A D D+G N E+ Y+       T
Sbjct: 921  EIIVLDENDNRPFFDNATYNFYLSEEDDIGAAVGTIHAVDNDVGGNGELTYSF------T 974

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR------YTVLVKATDQA 123
             N                 +F ++  +GA+ ++ SLDRE +        +++ V+  D  
Sbjct: 975  AN---------------HTLFTLNSVTGAITSKVSLDRESLVEAGQPTTFSIRVRVHDSG 1019

Query: 124  SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183
             P   +L   A ++++++D ND+ P F+ ++Y  SV E     +  +I ++ ATD DVG 
Sbjct: 1020 QP---QLQDHADVNIHVVDINDSPPVFNRESYQASVSE--LAQNETLIIRVSATDDDVGD 1074

Query: 184  NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
            NS I Y+I+ GN + +F ID + G + L+  LD E    Y L ++A+DGG   + +  ++
Sbjct: 1075 NSYILYSIVSGNEEKRFHIDHVHGQIVLIAPLDREVTEGYVLRVKARDGGIVPQESFVEV 1134

Query: 244  LINIRDVNDNAPRFYTSLFQE-SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
             I + D ND+ P F   L +E  V+E + IG +I  VQA D D   N +++YT+T     
Sbjct: 1135 EITVLDENDHRPSFSVDLQREIEVTECLQIGDTIGGVQATDMDINSNGQISYTITG---- 1190

Query: 303  GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
            GN+D    ++  SG VY +G LD E  ++Y L +TA DGG P   A  +           
Sbjct: 1191 GNLDGVFGVNANSGEVYLTGYLDHEATSQYSLNITARDGGSPSLQAVVSMVINIRDCNDN 1250

Query: 363  XXXF-MPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNG 419
               F   G  E++  E++P G  VV ++A+D+D   +  + + I+     G F       
Sbjct: 1251 SPIFAYVGVPEID--EEKPEGFEVVRVSASDSDSGVNGEVRFSISSQRPSGDFFAIDPES 1308

Query: 420  RGLITVAQPLDFKQE----RRYVLTVSATD-----SGGRSDTAMVQINITDANNYAPVFE 470
             G IT    +D + E     +++LTV  TD        R+ T  V I + D N+ AP F 
Sbjct: 1309 -GWITTNSRIDRESEIMATDQFILTVHGTDLAVPVESRRTATVDVVIFVRDINDNAPRF- 1366

Query: 471  NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
             +   A++       T V  V A D D G+N Q+TY+L S             F ++  T
Sbjct: 1367 TSQQAAAISRSTSANTRVTTVHADDPDTGVNGQVTYTLIST---------GVPFRLDLIT 1417

Query: 531  GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV--FKQQLYTA 588
            G +T  + +   + + Y L + A D G      +T   ++++  +    +  + Q  YT 
Sbjct: 1418 GELTLTQPIP-SSANIYSLDIRADDAGSNPQQQSTPFSLAIIISDGQSSILNYVQNTYTG 1476

Query: 589  NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR---EEGSFV-IDPASGVIRTNKA 644
            ++ E+   GT +  V A  +D G +  + Y +        ++GS +     +G+IRT+  
Sbjct: 1477 SVRENQPAGTEIVTVVAQYSD-GRSATVRYYVSAVTAGGVDKGSLIRASVTNGIIRTDAV 1535

Query: 645  LDRESV-ATHDLKAVAIDGGTPPQSS---TVIVHIKIEDINDSPPVFESDCLTFYISENS 700
            LDRE +     L A      T   SS   +V V + + D ND+ PVF +   T  I EN 
Sbjct: 1536 LDREDLGGGSSLVATVYAVDTSSSSSHVTSVQVTVNVLDENDNAPVFTNGPYTASIRENV 1595

Query: 701  PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760
               + +  + A D D   + ++ YSI  G  ++ FS+++  G    ++ T   +D ES  
Sbjct: 1596 ASNSPVKTVMATDAD--LDTIIFYSIVDG-ATDLFSIDSTTG----QIRTRGVVDRES-S 1647

Query: 761  KKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD 820
              Y+L ++A+   L +   ++I + D NDN PV       F   +D       G V A D
Sbjct: 1648 AVYQLQLQASDGTLTSTTTIDINLLDENDNDPVFSLSTYSFLVPEDEMVGEDVGVVVATD 1707

Query: 821  AD--VTDKLQYRIL--SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
             D  +  ++ Y ++       ++  L+  TG+  L   L+  V +   M V  TD
Sbjct: 1708 PDAGLNGEVAYSVVEEGAPGEDVFYLDPATGAFRLQQSLDYEVKQHYFMTVMATD 1762



 Score =  257 bits (629), Expect = 4e-66
 Identities = 211/700 (30%), Positives = 333/700 (47%), Gaps = 49/700 (7%)

Query: 209 VSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266
           VSLV    LD E    Y L I A D  S  R+    + + I DVNDN+P F  + +  +V
Sbjct: 42  VSLVTNSLLDRETEDFYILNISATDNSSTPRTGYLIVNVTITDVNDNSPIFTQTTYFATV 101

Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326
           +E+   G S+V + A D D+G N ++ Y + + + T N      +DP +GW+    QL  
Sbjct: 102 NESSAAGTSVVHLNATDIDQGSNGDIVYRLKN-ELTDN----FALDPDTGWITLLRQLPY 156

Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE------LAEDEP 380
                Y   VTATD G P +S++A                     E+E      ++E   
Sbjct: 157 VANG-YLFEVTATDKGSPSQSSSAFVNVMVEDENDHSPVIEVLIPEIEASGVASISETML 215

Query: 381 PGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQN-GRG----LITVAQPLDFKQ 433
           PG P+  L A D D  E+ R+   I  GN R  FS TS +   G    L+ V+   +  +
Sbjct: 216 PG-PLFNLKAIDEDREENGRVSMSIHSGNDRNDFSGTSISLPTGDVFFLLRVSPSANIDR 274

Query: 434 E--RRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
           E    Y LT +A D G   R     + I + D N++AP+F    Y A + E   +G+ V 
Sbjct: 275 EIIASYNLTFAAEDMGTPPRRTYRSIIIYVVDENDHAPMFLQESYRAGLLESIQVGSFVK 334

Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
            V+ATD+D GINA I YS++ +            F I+  TG +TT + LD ET +   L
Sbjct: 335 SVTATDADEGINADIVYSITGD--------EYGWFQIDNGTGLVTTREKLDHETAAQVTL 386

Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
           T+TA D G+  +++TT + I + DVND  PVF Q  Y+  + E++     + QV ATD D
Sbjct: 387 TITASDQGLEPMANTTILTIDIQDVNDEYPVFNQIAYSETVEENS-PARDLIQVLATDLD 445

Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669
            G+NG + Y     D+  G F +DP SG+++    LDRE   +++L+ +A DGG+P   +
Sbjct: 446 NGVNGDVTYTFS-SDQYSGMFSLDPESGLLQITVPLDREEQDSYELEILASDGGSPSLQA 504

Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729
           T  V I + D ND+PP F        + EN P G  +  + A D D G N  V +S+   
Sbjct: 505 TATVTIAVLDQNDNPPQFYPTEYYASVIENGPAGLFVTVVSATDLDVGVNGAVIFSL--- 561

Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTD 786
            DS+ F +++  G+    + T   LD E     Y L + A   +         + + VTD
Sbjct: 562 SDSSKFQIDSYSGN----VTTRESLDREQ-ESSYTLTVTAQDGSGQAAAQSATIFVTVTD 616

Query: 787 VNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETT 846
             DN    +     F   ++       G V A   D+  ++ Y I++G+   L +++  +
Sbjct: 617 TLDNPLEFELNPYRFQLEENRPNRTEVGTVLATSMDLNVEITYVIVNGDPNGLFVIDFYS 676

Query: 847 GSMTLSPQLNTNVPKLATMEVSV--TDGVNEIKAMMQLSV 884
           G +  +  ++    + A+  ++V   DG    + ++++ +
Sbjct: 677 GVIKTTLSIDREAHESASFRLTVLAVDGSQNGQTVVEIEI 716



 Score =  133 bits (322), Expect = 6e-29
 Identities = 146/585 (24%), Positives = 241/585 (41%), Gaps = 100/585 (17%)

Query: 1001 ICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILT 1060
            ICV  P  N E+C   +   +++  +NS+         +  F C+C  G++GV CE    
Sbjct: 3728 ICVCAPGYNGEDCKVEINECSSNPCINSECQDL-----INGFYCECSTGYSGVYCENGPC 3782

Query: 1061 KASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCELRARSFPVSSFLTFPG 1120
              S  V+G GS   SGS  V           C    ++    C+     F   S+++   
Sbjct: 3783 STSPCVNG-GSCVESGSTFV-----------CQCGNSHWGNRCQYDTIGFQAGSYISSSA 3830

Query: 1121 LKRRHRIHLKLKFATQTTSGLLLYN--GRYNERHDFLALELVSSEAGRGGGPGLRFSFSL 1178
            L+    + L L+F+T +T  LL YN     +    F+ALE++    GR     L+ SF+ 
Sbjct: 3831 LQSTSAVIL-LEFSTVSTKALLFYNHDSFTDSNAKFVALEILD---GR-----LQLSFNF 3881

Query: 1179 GGGKSEITVEGNVGDGSWHTVEIEYFNRTITM-ILD-DCDKVLSLAGAADFGLKYACANF 1236
            G G++ I+    V DG+WH VE+     ++ + ILD DC  + + A              
Sbjct: 3882 GSGQNSISASKPVSDGAWHKVEVRLEGMSVDLNILDEDCPSLSTDA-------------- 3927

Query: 1237 TRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPS----SFQVKNKDFVGCISDFYIDH 1292
                    C    ET         PL +GG+ +I      + QV   DFVGC++   ++ 
Sbjct: 3928 --------CRASQETTISLAFDNNPLTVGGVSDIAEITSRASQVSAADFVGCMNSIEVNG 3979

Query: 1293 KFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352
            + + +++    +  + GC   R  C    C +G+ C D W    CDC E  +G  CA+  
Sbjct: 3980 ERLSMSNARDHSNLVEGC--IREGCGETSCSDGSVCVDDWWKTWCDCDEMASGATCAEDN 4037

Query: 1353 GPPWRFGGDGMLSF---NPLLRPIQLPWLNALSIRTRQR--------------------- 1388
                 FGG G + +       R   L     L+ R R+R                     
Sbjct: 4038 NSV-SFGGGGRVDYTVKEDYKRQALLDDAKVLTRRRRRRASGSETVSLSFRTGVKDGLLL 4096

Query: 1389 ----DAFVMSIQLKSGLLHYSY------NGETMYLPMATLSDGAWHRIEIKWLGTDISVT 1438
                DA   ++QL +G + YSY      +G+ + +P ++L+DGAWH I +   G  +++T
Sbjct: 4097 YVTSDAEFTALQLSNGSVMYSYGSGSSSSGQIINIPSSSLTDGAWHNITLTSAGGQVTLT 4156

Query: 1439 VDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGLLASDVGFFEGCIQDVRIGTAQSLL 1498
            VD   ++ +     ++  G  +  + +GG +T   +    +  F GC+   ++      L
Sbjct: 4157 VDNAPKSAMFAD-PHEFTGLGLTGMALGGAETPLVINGRSIEGFTGCLDGFQMNGEGLPL 4215

Query: 1499 NRPTVR------ENVRDGCQSRADCMLSICPPYSKCVTSWDSSTC 1537
            +  + R          +GC     C L+ C     CV S    TC
Sbjct: 4216 DGDSQRFEAVPSAGTGEGCSPADLCALNPCSQGEACVPSETYYTC 4260



 Score =  130 bits (315), Expect = 4e-28
 Identities = 109/358 (30%), Positives = 163/358 (45%), Gaps = 22/358 (6%)

Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589
           T ++ TN LLDRET   Y+L ++A D      +    V +++ DVNDN P+F Q  Y A 
Sbjct: 41  TVSLVTNSLLDRETEDFYILNISATDNSSTPRTGYLIVNVTITDVNDNSPIFTQTTYFAT 100

Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES 649
           + E +  GTSV  + ATD D G NG I Y L  K+    +F +DP +G I   + L   +
Sbjct: 101 VNESSAAGTSVVHLNATDIDQGSNGDIVYRL--KNELTDNFALDPDTGWITLLRQLPYVA 158

Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT---- 705
              +  +  A D G+P QSS+  V++ +ED ND  PV E        S  + I  T    
Sbjct: 159 NG-YLFEVTATDKGSPSQSSSAFVNVMVEDENDHSPVIEVLIPEIEASGVASISETMLPG 217

Query: 706 -IGEIRAHDPDEGPNAVVHYSIKGGDDSNSF-----SLETRQGSDKAELVTMVDLDYESP 759
            +  ++A D D   N  V  SI  G+D N F     SL T        +    ++D E  
Sbjct: 218 PLFNLKAIDEDREENGRVSMSIHSGNDRNDFSGTSISLPTGDVFFLLRVSPSANIDREI- 276

Query: 760 RKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR- 815
              Y L   A    +PP      + I V D ND+AP+    +       +   VG F + 
Sbjct: 277 IASYNLTFAAEDMGTPPRRTYRSIIIYVVDENDHAPMFLQ-ESYRAGLLESIQVGSFVKS 335

Query: 816 VPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
           V A DAD  +   + Y I +G+      ++  TG +T   +L+       T+ ++ +D
Sbjct: 336 VTATDADEGINADIVYSI-TGDEYGWFQIDNGTGLVTTREKLDHETAAQVTLTITASD 392



 Score = 78.6 bits (185), Expect = 2e-12
 Identities = 83/374 (22%), Positives = 150/374 (40%), Gaps = 35/374 (9%)

Query: 1205 NRTITMILDDCDKVLSLAGAADFGLKYAC-ANFTRKVLPARCEIPTETCHRFLDLTGPL- 1262
            N  +  ++ + D V+ +          AC A F+ +    RCEIPT+ C +     G   
Sbjct: 3665 NINLEELITESDPVIFVGLQTSHSFTCACPAEFSGQ----RCEIPTDYCGQATCKNGATC 3720

Query: 1263 --QIGGLPNIPS---SFQVKNKDFVGCISDFYIDHKFIDL-NSYVADNGT-LAGCPEKRS 1315
               IGG   + +   + +    +   C S+  I+ +  DL N +  +  T  +G   +  
Sbjct: 3721 QNAIGGYICVCAPGYNGEDCKVEINECSSNPCINSECQDLINGFYCECSTGYSGVYCENG 3780

Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA-DSTG-PPWRFGGDGMLSFNPLLRPI 1373
             CS++PC NG  C +   T++C C   H G  C  D+ G     +     L     +  +
Sbjct: 3781 PCSTSPCVNGGSCVESGSTFVCQCGNSHWGNRCQYDTIGFQAGSYISSSALQSTSAVILL 3840

Query: 1374 QLPWLNALSIRTRQRDAFV------MSIQLKSGLLHYSYN---GETMYLPMATLSDGAWH 1424
            +   ++  ++     D+F       +++++  G L  S+N   G+        +SDGAWH
Sbjct: 3841 EFSTVSTKALLFYNHDSFTDSNAKFVALEILDGRLQLSFNFGSGQNSISASKPVSDGAWH 3900

Query: 1425 RIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYI------GKILIGGLDTTAGLL--A 1476
            ++E++  G  + + +       L        Q   I        + +GG+   A +   A
Sbjct: 3901 KVEVRLEGMSVDLNILDEDCPSLSTDACRASQETTISLAFDNNPLTVGGVSDIAEITSRA 3960

Query: 1477 SDVGF--FEGCIQDVRIGTAQSLLNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDS 1534
            S V    F GC+  + +   +  ++      N+ +GC  R  C  + C   S CV  W  
Sbjct: 3961 SQVSAADFVGCMNSIEVNGERLSMSNARDHSNLVEGC-IREGCGETSCSDGSVCVDDWWK 4019

Query: 1535 STCTCEAGRVGPQC 1548
            + C C+    G  C
Sbjct: 4020 TWCDCDEMASGATC 4033



 Score = 40.7 bits (91), Expect = 0.57
 Identities = 16/38 (42%), Positives = 20/38 (52%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGP 1354
            C    C NG  CSD   +  C+C EG++G  C   TGP
Sbjct: 4265 CVPDVCLNGGVCSDGTGSVTCECAEGYSGDYCEGGTGP 4302


>UniRef50_Q4SFW8 Cluster: Chromosome 7 SCAF14601, whole genome shotgun
            sequence; n=4; Eumetazoa|Rep: Chromosome 7 SCAF14601,
            whole genome shotgun sequence - Tetraodon nigroviridis
            (Green puffer)
          Length = 2970

 Score =  394 bits (969), Expect = e-107
 Identities = 397/1411 (28%), Positives = 617/1411 (43%), Gaps = 140/1411 (9%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ +LD ND++P+FE   Y A+V EG   GT V+ ++A D D G N +V Y +E  ++D 
Sbjct: 1549 EVKILDVNDNNPLFETNTYVATVMEGMPIGTRVVQVRALDPDWGANGQVCY-VEAASSD- 1606

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
              P  +             VF ID ++G + T + +D E  + Y+  V A+D     S  
Sbjct: 1607 -GPITSSS-----------VFAIDSKTGWITTVSEMDHEACSSYSFEVVASDLGELRS-- 1652

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSAIR 188
            LSST  + + + D NDN P+F  + Y  +V E  S+ +  V+A +K +D D    N  + 
Sbjct: 1653 LSSTTVVTIAVSDCNDNPPRFERELYRGAVKESDSLGE--VVAVLKTSDRDGTDQNRLVS 1710

Query: 189  YAIIGGNTQMQFSIDSLSGD--VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            + I GGN +  F +  + G+  V +   LD EQ   Y L I A DG   +    T + + 
Sbjct: 1711 FYISGGNPRGVFGLAPVQGEWKVYVSGLLDREQQDWYLLNITASDGLYVAH---TAVEVT 1767

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            + D NDN P    +++  S  E++P+   I+ V A DAD G +AE+ Y++      G  D
Sbjct: 1768 VMDANDNRPICNQAVYSASFPEDIPVNKGILTVAATDADSGSSAEIQYSLFG---IGVED 1824

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
                +D  +G + T+  +DRET   Y+L+  ATDGG       +               F
Sbjct: 1825 F--YMDANTGELRTATIMDRETTPSYKLIAQATDGGG--LFCRSDISLKVLDVNDNAPTF 1880

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
                Y   + E+  P   +  L A+D DE        T  +    FSI   +G  ++ + 
Sbjct: 1881 SSPHYLASVYENAAPKALLTRLQASDPDEGLNRTLVYTLDSIDELFSIDPVSG--MVVLE 1938

Query: 427  QPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT----DANNYAPVFENAPYTASVFEDA 482
            + LD + +  Y L V ATD  G+      Q+N+T    D N+ APVF+   Y  +V ED 
Sbjct: 1939 KSLDRESQDSYRLRVQATDQAGQRGALSTQVNLTILVLDVNDNAPVFQRRDYGVTVPEDV 1998

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
             +GT VL V AT  D+G+NA+I+Y + S   NE       +F I+   G+I     LD E
Sbjct: 1999 AVGTEVLRVLATSVDIGLNAEISYRIRS--GNEL-----GKFNIDTNLGSIFVADDLDFE 2051

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
                Y LT+ A DGG P LS  T V I ++DVNDN P F Q +Y   + EDA VG  V++
Sbjct: 2052 VCKDYYLTIEAWDGGNPPLSSATVVTIDLMDVNDNAPTFSQDIYNVLVSEDASVGQMVTR 2111

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
            V A D D   NGRI Y +   DR    F IDP +G+++ NK LDRE V+ + L   A D 
Sbjct: 2112 VSAEDLDSQGNGRITYSILKGDR-NNHFWIDPVTGILKVNKRLDRELVSRYSLSVQAFDS 2170

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVFESD-------------CLTF---YISENSPI---- 702
            G+P  SSTV ++I I DIND+ PVF                 L F   YIS   P+    
Sbjct: 2171 GSPAMSSTVTLNIDISDINDNSPVFTPPNSTAIIQVPAPALLLVFVRSYISLPPPLSHLQ 2230

Query: 703  -----GTTIGEIRAHDPDEGPNA-VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756
                 G+T+ ++   D D   N     + I  G++ N FSL+ + G+ K+  V     D 
Sbjct: 2231 LNQAAGSTLLKLSVSDKDSPKNGPPFDFRIVSGNEENFFSLD-QAGTLKSNRV----FDP 2285

Query: 757  ESPRK-KYEL-VIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG 814
            E+PR+   E+ V  +  P L     V + V   +   P++   +I      D FP GP G
Sbjct: 2286 EAPREFTLEIQVSDSGKPRLAASSWVFLRVIGNSQYKPLVSPLEIFIVMATDTFPGGPIG 2345

Query: 815  RVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN 874
            R+ A D D  D L +      + ++  +N   G++   P L    P    +  +V+DG  
Sbjct: 2346 RIYATDRDPNDVLSF-TQKLQSKSMFKINRQDGTVVAVPGLE---PGRYQINATVSDGRF 2401

Query: 875  EIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLL---GFFIDGLAA--IIPCPKE 929
             + A + + V  +T+ +L +++T+R + ++ E  L   L      + GLA     P  ++
Sbjct: 2402 AVIADVSVQVEQVTDVLLRSALTLRFSSLSPEDLLGRYLRQIKLILRGLAGWKWSPGQQD 2461

Query: 930  NIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERV-YLHRTTLAR 988
             ++I S++  +  +G  +++  +  RP  E   +G     YS   L  ++    +  L R
Sbjct: 2462 PLHIISLKPVSGTSG--VDLLLAMERP--ETAGSGRIGGFYSQQELTVKLEEAAQRGLIR 2517

Query: 989  LATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFV-NSDSVLFRPIYPVTSFTCQCP 1047
                  +           C +   C   L     S    +++ V    +   T+  C CP
Sbjct: 2518 GVLAGAVAVGSTCSGELECGDSLVCEQKLVMEEGSPLTYSTERVSLVSLAFGTTEACTCP 2577

Query: 1048 EGF--TGVN-CETILTKASCEVDGDGSICRSGSQCVARR----EGGILCQGCSIDAAYTT 1100
             G   T V  CE     A  +    G    S  QC+  R     G ++     + +    
Sbjct: 2578 GGACPTPVELCEGQSCPADMQCVRSGPTAPSVCQCLPERLDQCAGAVISSSLYLGSNSNV 2637

Query: 1101 A--------VCELRARSFPVSSFLTF--PGLKRRHRIHLKLKFATQTTSGLLLYNGRYNE 1150
                     V +  + SF  +S++ +      +   + L L+  T    G+++Y  R N 
Sbjct: 2638 TKNFKSDLLVTDQTSLSFSGNSYIKYRVSDGGQNGEMKLSLRIRTLQRRGVIMYT-RVN- 2695

Query: 1151 RHDFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGN-VGDGSWHTVEIEYFNRTIT 1209
                    ++  E GR     L F          + +    + DG WH V +E  +    
Sbjct: 2696 -----PCTMLKIEGGR-----LWFQLDCDNTLGIMGISDRPINDGLWHAVALELTSNYTL 2745

Query: 1210 MILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPN 1269
            + LDD       A  A   L +  A  +     A+   P+    +     GP +  G P 
Sbjct: 2746 LSLDDSYVERRRAARAPVRL-WPLAPDSSFFFGAQVRPPSVQGEK----PGPGRTQGGPA 2800

Query: 1270 IPSS---FQVKNK-DFVGCISDFYIDHKFIDLNSYVADNGTLA-------GCPEKRSRCS 1318
            +  S    Q K +  F GC+    ++   + L +  +    +A       GC      C 
Sbjct: 2801 LGDSGTRSQPKAQGGFQGCLGSLMLNGNELPLQNKRSRYAEIAGLSDVKLGCVLYPDPCV 2860

Query: 1319 SAPCYNGAECSDL-WDTYICDCKEGHTGKDC 1348
            S PC NGA CS L    + C C  G TG  C
Sbjct: 2861 SQPCLNGAMCSSLPSGGFACSCSAGFTGARC 2891



 Score =  359 bits (882), Expect = 8e-97
 Identities = 277/882 (31%), Positives = 428/882 (48%), Gaps = 57/882 (6%)

Query: 5    FCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIEL 64
            FC  + I + D ND+ P F   +Y  S++   + G+ V  ++A+D D G N  + Y+  L
Sbjct: 1330 FCSVRVI-LADENDNPPRFRAVEYRMSIKANVAKGSLVTQIQASDPDAGSNGRITYS--L 1386

Query: 65   VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS 124
             +   L+  D           V +V R    SG ++T++++D  +    +  VKATD  S
Sbjct: 1387 YSEARLSLVD-----------VLEVSRF--YSGWMMTKSNVDHLQGTVLSFFVKATDSGS 1433

Query: 125  PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184
            P    L S A IHV  +  +   P FS+  Y+ ++ ED  V     +  +       G  
Sbjct: 1434 PAKHSLVS-AFIHV--VPPDAFVPSFSQPQYSFTIPEDTVV--GTALGSVYMGPGQTGFF 1488

Query: 185  SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT-QL 243
            +A+   ++  N    F +D  SG + L K LDYE+V  +R  +          + TT  L
Sbjct: 1489 TAVVGEMVDSNQGGTFLVDRESGLIRLSKPLDYEEVSIFRFKVAVTTRRDLIEAVTTVDL 1548

Query: 244  LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT-MTDKDYT 302
             + I DVNDN P F T+ +  +V E +PIG  +V+V+A D D G N ++ Y      D  
Sbjct: 1549 EVKILDVNDNNPLFETNTYVATVMEGMPIGTRVVQVRALDPDWGANGQVCYVEAASSDGP 1608

Query: 303  GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD-PPRSATATXXXXXXXXXX 361
                    ID ++GW+ T  ++D E  + Y   V A+D G+    S+T            
Sbjct: 1609 ITSSSVFAIDSKTGWITTVSEMDHEACSSYSFEVVASDLGELRSLSSTTVVTIAVSDCND 1668

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRL-HYEITGGNTRGRFSITSQN 418
                F    Y   + E +  G  V  L  +D D  + NRL  + I+GGN RG F +    
Sbjct: 1669 NPPRFERELYRGAVKESDSLGEVVAVLKTSDRDGTDQNRLVSFYISGGNPRGVFGLAPVQ 1728

Query: 419  GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASV 478
            G   + V+  LD +Q+  Y+L ++A+D    + TA V++ + DAN+  P+   A Y+AS 
Sbjct: 1729 GEWKVYVSGLLDREQQDWYLLNITASDGLYVAHTA-VEVTVMDANDNRPICNQAVYSASF 1787

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             ED P+   +L V+ATD+D G +A+I YSL   I  E        F ++  TG + T  +
Sbjct: 1788 PEDIPVNKGILTVAATDADSGSSAEIQYSLFG-IGVE-------DFYMDANTGELRTATI 1839

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            +DRET   Y L   A DGG   L   +D+ + V+DVNDN P F    Y A++ E+A    
Sbjct: 1840 MDRETTPSYKLIAQATDGG--GLFCRSDISLKVLDVNDNAPTFSSPHYLASVYENAAPKA 1897

Query: 599  SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
             ++++ A+D D GLN  + Y LD  D     F IDP SG++   K+LDRES  ++ L+  
Sbjct: 1898 LLTRLQASDPDEGLNRTLVYTLDSIDE---LFSIDPVSGMVVLEKSLDRESQDSYRLRVQ 1954

Query: 659  AID--GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
            A D  G     S+ V + I + D+ND+ PVF+       + E+  +GT +  + A   D 
Sbjct: 1955 ATDQAGQRGALSTQVNLTILVLDVNDNAPVFQRRDYGVTVPEDVAVGTEVLRVLATSVDI 2014

Query: 717  GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPP 773
            G NA + Y I+ G++   F+++T  GS    +    DLD+E   K Y L I A    +PP
Sbjct: 2015 GLNAEISYRIRSGNELGKFNIDTNLGS----IFVADDLDFE-VCKDYYLTIEAWDGGNPP 2069

Query: 774  LWNDVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVGPF-GRVPAYDADV--TDKLQY 829
            L +   V I + DVNDNAP     Q I+N    +   VG    RV A D D     ++ Y
Sbjct: 2070 LSSATVVTIDLMDVNDNAPTFS--QDIYNVLVSEDASVGQMVTRVSAEDLDSQGNGRITY 2127

Query: 830  RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
             IL G+  N   ++  TG + ++ +L+  +    ++ V   D
Sbjct: 2128 SILKGDRNNHFWIDPVTGILKVNKRLDRELVSRYSLSVQAFD 2169



 Score =  307 bits (754), Expect = 3e-81
 Identities = 227/720 (31%), Positives = 343/720 (47%), Gaps = 45/720 (6%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            F +D  SG +     LD E+V+ +   V  T +   +     +T  + V I+D NDN P 
Sbjct: 1504 FLVDRESGLIRLSKPLDYEEVSIFRFKVAVTTRRDLIE--AVTTVDLEVKILDVNDNNPL 1561

Query: 150  FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN-----TQMQFSIDS 204
            F   TY  +V E + +     + +++A D D GAN  + Y     +     +   F+IDS
Sbjct: 1562 FETNTYVATVMEGMPIGTR--VVQVRALDPDWGANGQVCYVEAASSDGPITSSSVFAIDS 1619

Query: 205  LSGDVSLVKTLDYEQVRSYRLVIRAQDGGS-PSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263
             +G ++ V  +D+E   SY   + A D G   S S+TT + I + D NDN PRF   L++
Sbjct: 1620 KTGWITTVSEMDHEACSSYSFEVVASDLGELRSLSSTTVVTIAVSDCNDNPPRFERELYR 1679

Query: 264  ESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYTGNVDLPITIDPRSG-W-VYT 320
             +V E+  +G  +  ++  D D    N  +++ ++     GN      + P  G W VY 
Sbjct: 1680 GAVKESDSLGEVVAVLKTSDRDGTDQNRLVSFYISG----GNPRGVFGLAPVQGEWKVYV 1735

Query: 321  SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380
            SG LDRE Q  Y L +TA+DG     +A                  +   Y     ED P
Sbjct: 1736 SGLLDREQQDWYLLNITASDGLYVAHTAVEVTVMDANDNRPICNQAV---YSASFPEDIP 1792

Query: 381  PGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYV 438
                ++T+ ATDAD  +   + Y + G      F + +  G   +  A  +D +    Y 
Sbjct: 1793 VNKGILTVAATDADSGSSAEIQYSLFGIGVED-FYMDANTGE--LRTATIMDRETTPSYK 1849

Query: 439  LTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498
            L   ATD GG    + + + + D N+ AP F +  Y ASV+E+A     +  + A+D D 
Sbjct: 1850 LIAQATDGGGLFCRSDISLKVLDVNDNAPTFSSPHYLASVYENAAPKALLTRLQASDPDE 1909

Query: 499  GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD--G 556
            G+N  + Y+L S          D+ F I+P +G +   K LDRE+   Y L V A D  G
Sbjct: 1910 GLNRTLVYTLDSI---------DELFSIDPVSGMVVLEKSLDRESQDSYRLRVQATDQAG 1960

Query: 557  GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616
               +LS   ++ I V+DVNDN PVF+++ Y   + ED  VGT V +V AT  D+GLN  I
Sbjct: 1961 QRGALSTQVNLTILVLDVNDNAPVFQRRDYGVTVPEDVAVGTEVLRVLATSVDIGLNAEI 2020

Query: 617  HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676
             Y +     E G F ID   G I     LD E    + L   A DGG PP SS  +V I 
Sbjct: 2021 SYRIR-SGNELGKFNIDTNLGSIFVADDLDFEVCKDYYLTIEAWDGGNPPLSSATVVTID 2079

Query: 677  IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736
            + D+ND+ P F  D     +SE++ +G  +  + A D D   N  + YSI  GD +N F 
Sbjct: 2080 LMDVNDNAPTFSQDIYNVLVSEDASVGQMVTRVSAEDLDSQGNGRITYSILKGDRNNHFW 2139

Query: 737  LETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPV 793
            ++   G  K      +D +  S   +Y L ++A    SP + + V + I ++D+NDN+PV
Sbjct: 2140 IDPVTGILKVN--KRLDRELVS---RYSLSVQAFDSGSPAMSSTVTLNIDISDINDNSPV 2194



 Score =  267 bits (654), Expect = 3e-69
 Identities = 243/905 (26%), Positives = 399/905 (44%), Gaps = 86/905 (9%)

Query: 13   VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72
            VLD ND++P+F+   Y + + E    GTTVL + A DQD  KNA V Y I    +D  N 
Sbjct: 994  VLDVNDNAPLFQNTSYSSVLPENVMIGTTVLKVFAQDQDSEKNAIVSYQI---LSDIYNS 1050

Query: 73   EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132
             D               F ID  SG +     LD E V R+  +V+ATD   P    LSS
Sbjct: 1051 TD--------------YFHIDSSSGLIFMARRLDYELVQRHNFIVRATDSGDPT---LSS 1093

Query: 133  TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192
              ++ V + D NDN P FS+  Y   V E ++  D+  +  ++A+DAD+     +RY+I+
Sbjct: 1094 DVSVTVTVTDTNDNPPNFSQTLYEAFVSE-LAPRDH-FVTCVQASDADICDAQRLRYSIV 1151

Query: 193  GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252
             GN +M F ++  +G + L          SY+L +   DG     +NT Q+++ +   N 
Sbjct: 1152 SGNERMTFLMEPDTGVLRLSNKRRQGMKLSYQLNVSVSDG---VFTNTAQVIVQVLGANL 1208

Query: 253  NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV-----------NAELTYTM----T 297
             +P F    +   V EN P G  +++V  +     +             E T T+    T
Sbjct: 1209 YSPVFSQRFYLAEVQENAPPGSKVIQVSLFFHSNTLIRMCPAVQPLKPLECTMTLQVRAT 1268

Query: 298  DKD--YTGNVDLPITID--------PRSGWVYTSGQLDRETQAKYQLLVT--ATDGGDPP 345
            D+D    G +      D          +G + T  +LDRE      +++T  A DGG   
Sbjct: 1269 DEDSGLFGQITYSFVNDLGKTKFAVDAAGIISTLEKLDRENPLYKDMVLTVMALDGGG-- 1326

Query: 346  RSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEI 403
            R++  +              F   +Y + +  +   G+ V  + A+D D   + R+ Y +
Sbjct: 1327 RASFCSVRVILADENDNPPRFRAVEYRMSIKANVAKGSLVTQIQASDPDAGSNGRITYSL 1386

Query: 404  TGGNTRGRFSI--TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ--INI 459
                      +   S+   G +     +D  Q       V ATDSG  +  ++V   I++
Sbjct: 1387 YSEARLSLVDVLEVSRFYSGWMMTKSNVDHLQGTVLSFFVKATDSGSPAKHSLVSAFIHV 1446

Query: 460  TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAH 519
               + + P F    Y+ ++ ED  +GT +  V       G         ++ +     ++
Sbjct: 1447 VPPDAFVPSFSQPQYSFTIPEDTVVGTALGSVYMGPGQTGF-------FTAVVGEMVDSN 1499

Query: 520  HDQQFVINPQTGAITTNKLLDRETMS--GYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577
                F+++ ++G I  +K LD E +S   + + VT R   + +++ T D+E+ ++DVNDN
Sbjct: 1500 QGGTFLVDRESGLIRLSKPLDYEEVSIFRFKVAVTTRRDLIEAVT-TVDLEVKILDVNDN 1558

Query: 578  EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY----ELDPKDREEGSFVID 633
             P+F+   Y A +ME   +GT V QV A D D G NG++ Y      D        F ID
Sbjct: 1559 NPLFETNTYVATVMEGMPIGTRVVQVRALDPDWGANGQVCYVEAASSDGPITSSSVFAID 1618

Query: 634  PASGVIRTNKALDRESVATHDLKAVAID-GGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692
              +G I T   +D E+ +++  + VA D G     SST +V I + D ND+PP FE +  
Sbjct: 1619 SKTGWITTVSEMDHEACSSYSFEVVASDLGELRSLSSTTVVTIAVSDCNDNPPRFERELY 1678

Query: 693  TFYISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751
               + E+  +G  +  ++  D D    N +V + I GG+    F L   QG  K  +  +
Sbjct: 1679 RGAVKESDSLGEVVAVLKTSDRDGTDQNRLVSFYISGGNPRGVFGLAPVQGEWKVYVSGL 1738

Query: 752  VDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPV 810
            +D + +     Y L I A+         VE+ V D NDN P+    Q +++ ++ +  PV
Sbjct: 1739 LDREQQD---WYLLNITASDGLYVAHTAVEVTVMDANDNRPICN--QAVYSASFPEDIPV 1793

Query: 811  GP-FGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867
                  V A DAD   + ++QY  L G       ++  TG +  +  ++        +  
Sbjct: 1794 NKGILTVAATDADSGSSAEIQYS-LFGIGVEDFYMDANTGELRTATIMDRETTPSYKLIA 1852

Query: 868  SVTDG 872
              TDG
Sbjct: 1853 QATDG 1857



 Score =  262 bits (643), Expect = 7e-68
 Identities = 245/867 (28%), Positives = 397/867 (45%), Gaps = 82/867 (9%)

Query: 43   LTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQ----DV-FRIDGRSG 97
            ++L  +D    K ++ EY  E++T  T                +     D+ F I+  +G
Sbjct: 372  ISLMLSDYSSPKFSQKEYQAEVLTTGTHVATVTALSRSALFYDISRGNDDLCFYINHHTG 431

Query: 98   ALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTV 157
             + TR  LD E+   Y ++V A         R+ ++ T+ V + D NDN P F +  Y  
Sbjct: 432  VINTRKLLDFEQTPSYFLVVHALSMT-----RMEASTTVTVQVGDVNDNSPVFQQLRYVG 486

Query: 158  SVDEDISVTD-------NPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVS 210
            ++ E   V         NP++  I+ATD D   N+ + + I+    +M FSIDS +G + 
Sbjct: 487  TISEAAPVNSVVLGDDGNPLV--IQATDMDRNHNALLVFHILDETARMFFSIDSGTGSIR 544

Query: 211  LVKTLDYEQVRSYRLVIRAQDGGSPSRS--NTTQLLINIRDVNDNAPRFYTSLFQESVSE 268
             + +LDYE    +   +  +D G P RS  +   + I + ++ND+ P+     ++  +  
Sbjct: 545  TIASLDYEIFSEFFFQVYVRDSGQPPRSADSPADVFIKVININDSPPKLSQDTYETVLLL 604

Query: 269  NVPIGYSIVRVQAYDAD-------EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321
                G  +++V+A D D       + V  +L Y++ +     NV+   ++D  SG V  +
Sbjct: 605  PTYAGVEVLQVEASDPDMTSDFTLKSVTPQLVYSLVES----NVE-NFSVDRFSGTVTVA 659

Query: 322  G-QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380
               L+++   +YQ  V   DG     ++ A+              +   +Y   + E+  
Sbjct: 660  NPNLNKD---RYQFTVKVWDGRF---TSMASVTVLVRKAIDSGLLYTSPEYFASIPENIS 713

Query: 381  PGTPVVTLTATDADEDNR-LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY-- 437
              T VVT+ +T     N  L Y +   N   RF I    G  ++T   P D +    Y  
Sbjct: 714  NVT-VVTVVSTIGHRLNEPLRYTLL--NAGERFVIRPTCGV-VLTTGVPFDRELADSYEL 769

Query: 438  VLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497
            V+ VS  D   R     VQ+ + D N+ AP F N PY A+V  DA   + +  VSA D D
Sbjct: 770  VVEVSREDEILRVARVTVQVQVEDVNDNAPEFVNLPYYAAVQVDAEPESAIFKVSAVDRD 829

Query: 498  VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG-YLLTVTARDG 556
             G+N +++YSL  +  N         F +NP TG +T  K  + +  +  Y L + A DG
Sbjct: 830  TGVNGEVSYSLKQQHRN---------FQMNPVTGELTLKKAFESDLSNAEYKLVLVATDG 880

Query: 557  GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616
            G P LS   +VE+ V  VN   PVF +  Y   + ED  V TS+  + A+  +  +    
Sbjct: 881  GFPPLS--REVELPVTVVNKAMPVFDKPFYGVTVREDVAVSTSILGINASSPEGQIVIFT 938

Query: 617  HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676
              + DP  +    F I   +G I     LD E+   + L   A D  T  +S  V V + 
Sbjct: 939  IIDGDPSFQ----FDIGFDTGTISVIYPLDYETTQYYRLTVKATDTQTGAKSE-VDVDVV 993

Query: 677  IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG--DDSNS 734
            + D+ND+ P+F++   +  + EN  IGTT+ ++ A D D   NA+V Y I     + ++ 
Sbjct: 994  VLDVNDNAPLFQNTSYSSVLPENVMIGTTVLKVFAQDQDSEKNAIVSYQILSDIYNSTDY 1053

Query: 735  FSLETRQGSDKAELVTMVD-LDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDN 790
            F +++  G     L+ M   LDYE  ++ +  ++RA     P L +DV V + VTD NDN
Sbjct: 1054 FHIDSSSG-----LIFMARRLDYELVQR-HNFIVRATDSGDPTLSSDVSVTVTVTDTNDN 1107

Query: 791  APVMKDFQIIFNNY-KDCFPVGPFGR-VPAYDADVTD--KLQYRILSGNNANLILLNETT 846
             P     Q ++  +  +  P   F   V A DAD+ D  +L+Y I+SGN     L+   T
Sbjct: 1108 PPNFS--QTLYEAFVSELAPRDHFVTCVQASDADICDAQRLRYSIVSGNERMTFLMEPDT 1165

Query: 847  GSMTLSPQLNTNVPKLATMEVSVTDGV 873
            G + LS +    +     + VSV+DGV
Sbjct: 1166 GVLRLSNKRRQGMKLSYQLNVSVSDGV 1192



 Score =  248 bits (606), Expect = 2e-63
 Identities = 246/888 (27%), Positives = 400/888 (45%), Gaps = 96/888 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V D ND+ P F    Y+A   E +  GT+VL + A D+D G N ++ YTIE     + 
Sbjct: 267  VAVEDSNDNIPYFTSTVYDAVAYESSPFGTSVLQVTALDKDNGINGQLTYTIEAGNTGS- 325

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                              VF ID  +G +    +LD   V  YT+ V+ +D   P    L
Sbjct: 326  ------------------VFGIDAATGLIFIARALDLTSVGFYTLTVRVSDSGFP---PL 364

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             +TA++ ++++  + + P+FS+K Y   V     +T    +A + A      + SA+ Y 
Sbjct: 365  MATASVRISLMLSDYSSPKFSQKEYQAEV-----LTTGTHVATVTAL-----SRSALFYD 414

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I  GN  + F I+  +G ++  K LD+EQ  SY LV+ A        S T  + + + DV
Sbjct: 415  ISRGNDDLCFYINHHTGVINTRKLLDFEQTPSYFLVVHALSMTRMEASTT--VTVQVGDV 472

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVR-------VQAYDADEGVNAELTYTMTDKDYTG 303
            NDN+P F    +  ++SE  P+   ++        +QA D D   NA L + + D+    
Sbjct: 473  NDNSPVFQQLRYVGTISEAAPVNSVVLGDDGNPLVIQATDMDRNHNALLVFHILDE---- 528

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA--TATXXXXXXXXXX 361
               +  +ID  +G + T   LD E  +++   V   D G PPRSA   A           
Sbjct: 529  TARMFFSIDSGTGSIRTIASLDYEIFSEFFFQVYVRDSGQPPRSADSPADVFIKVININD 588

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN---------RLHYEITGGNTRGRF 412
                     YE  L      G  V+ + A+D D  +         +L Y +   N    F
Sbjct: 589  SPPKLSQDTYETVLLLPTYAGVEVLQVEASDPDMTSDFTLKSVTPQLVYSLVESNVE-NF 647

Query: 413  SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENA 472
            S+      G +TVA P   K   RY  TV   D G  +  A V + +  A +   ++ + 
Sbjct: 648  SV--DRFSGTVTVANPNLNKD--RYQFTVKVWD-GRFTSMASVTVLVRKAIDSGLLYTSP 702

Query: 473  PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
             Y AS+ E+    T V VVS       +N  + Y+L          +  ++FVI P  G 
Sbjct: 703  EYFASIPENISNVTVVTVVSTIGH--RLNEPLRYTL---------LNAGERFVIRPTCGV 751

Query: 533  I-TTNKLLDRETMSGYLLTV-TARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590
            + TT    DRE    Y L V  +R+  +  ++  T V++ V DVNDN P F    Y A +
Sbjct: 752  VLTTGVPFDRELADSYELVVEVSREDEILRVARVT-VQVQVEDVNDNAPEFVNLPYYAAV 810

Query: 591  MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE-S 649
              DA   +++ +V A D D G+NG + Y L  + R   +F ++P +G +   KA + + S
Sbjct: 811  QVDAEPESAIFKVSAVDRDTGVNGEVSYSLKQQHR---NFQMNPVTGELTLKKAFESDLS 867

Query: 650  VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
             A + L  VA DGG PP S  V + + +  +N + PVF+       + E+  + T+I  I
Sbjct: 868  NAEYKLVLVATDGGFPPLSREVELPVTV--VNKAMPVFDKPFYGVTVREDVAVSTSILGI 925

Query: 710  RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
             A  P+     +V ++I  GD S  F +    G D   +  +  LDYE+  + Y L ++A
Sbjct: 926  NASSPE---GQIVIFTIIDGDPSFQFDI----GFDTGTISVIYPLDYET-TQYYRLTVKA 977

Query: 770  ASPPLW--NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK- 826
                    ++V V+++V DVNDNAP+ ++        ++        +V A D D     
Sbjct: 978  TDTQTGAKSEVDVDVVVLDVNDNAPLFQNTSYSSVLPENVMIGTTVLKVFAQDQDSEKNA 1037

Query: 827  -LQYRILSG--NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
             + Y+ILS   N+ +   ++ ++G + ++ +L+  + +     V  TD
Sbjct: 1038 IVSYQILSDIYNSTDYFHIDSSSGLIFMARRLDYELVQRHNFIVRATD 1085



 Score =  242 bits (592), Expect = 1e-61
 Identities = 199/720 (27%), Positives = 321/720 (44%), Gaps = 31/720 (4%)

Query: 173  KIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQ--VRSYRLVIRAQ 230
            +++ATD D G    I Y+ +    + +F++D+ +G +S ++ LD E    +   L + A 
Sbjct: 1264 QVRATDEDSGLFGQITYSFVNDLGKTKFAVDA-AGIISTLEKLDRENPLYKDMVLTVMAL 1322

Query: 231  DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290
            DGG   R++   + + + D NDN PRF    ++ S+  NV  G  + ++QA D D G N 
Sbjct: 1323 DGGG--RASFCSVRVILADENDNPPRFRAVEYRMSIKANVAKGSLVTQIQASDPDAGSNG 1380

Query: 291  ELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350
             +TY++  +     VD+       SGW+ T   +D          V ATD G P + +  
Sbjct: 1381 RITYSLYSEARLSLVDVLEVSRFYSGWMMTKSNVDHLQGTVLSFFVKATDSGSPAKHSLV 1440

Query: 351  TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV--VTLTATDADEDNRLHYEITGGNT 408
            +              F   QY   + ED   GT +  V +          +  E+   N 
Sbjct: 1441 SAFIHVVPPDAFVPSFSQPQYSFTIPEDTVVGTALGSVYMGPGQTGFFTAVVGEMVDSNQ 1500

Query: 409  RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT---DSGGRSDTAMVQINITDANNY 465
             G F +  ++  GLI +++PLD+++   +   V+ T   D      T  +++ I D N+ 
Sbjct: 1501 GGTFLVDRES--GLIRLSKPLDYEEVSIFRFKVAVTTRRDLIEAVTTVDLEVKILDVNDN 1558

Query: 466  APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525
             P+FE   Y A+V E  PIGT V+ V A D D G N Q+ Y  ++  S++        F 
Sbjct: 1559 NPLFETNTYVATVMEGMPIGTRVVQVRALDPDWGANGQVCYVEAA--SSDGPITSSSVFA 1616

Query: 526  INPQTGAITTNKLLDRETMSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584
            I+ +TG ITT   +D E  S Y   V A D G + SLS TT V I+V D NDN P F+++
Sbjct: 1617 IDSKTGWITTVSEMDHEACSSYSFEVVASDLGELRSLSSTTVVTIAVSDCNDNPPRFERE 1676

Query: 585  LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG--VIRTN 642
            LY   + E   +G  V+ +  +D D     R+           G F + P  G   +  +
Sbjct: 1677 LYRGAVKESDSLGEVVAVLKTSDRDGTDQNRLVSFYISGGNPRGVFGLAPVQGEWKVYVS 1736

Query: 643  KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
              LDRE    + L   A DG     ++   V + + D ND+ P+      +    E+ P+
Sbjct: 1737 GLLDREQQDWYLLNITASDGLYVAHTA---VEVTVMDANDNRPICNQAVYSASFPEDIPV 1793

Query: 703  GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762
               I  + A D D G +A + YS+  G     F ++   G    EL T   +D E+    
Sbjct: 1794 NKGILTVAATDADSGSSAEIQYSL-FGIGVEDFYMDANTG----ELRTATIMDRET-TPS 1847

Query: 763  YELVIRAA-SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDA 821
            Y+L+ +A     L+    + + V DVNDNAP       + + Y++  P     R+ A D 
Sbjct: 1848 YKLIAQATDGGGLFCRSDISLKVLDVNDNAPTFSSPHYLASVYENAAPKALLTRLQASDP 1907

Query: 822  D--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAM 879
            D  +   L Y + S +   L  ++  +G + L   L+        + V  TD   +  A+
Sbjct: 1908 DEGLNRTLVYTLDSID--ELFSIDPVSGMVVLEKSLDRESQDSYRLRVQATDQAGQRGAL 1965



 Score =  241 bits (589), Expect = 3e-61
 Identities = 244/901 (27%), Positives = 389/901 (43%), Gaps = 71/901 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVL---------TLKATDQDIGKNAEVEYT 61
            + VL  N +SPVF  + Y A V+E A  G+ V+         TL      +     +E T
Sbjct: 1201 VQVLGANLYSPVFSQRFYLAEVQENAPPGSKVIQVSLFFHSNTLIRMCPAVQPLKPLECT 1260

Query: 62   IELVTADTLNPEDAXXXXXXXXXXVQDV----FRIDGRSGALLTRASLDREKVARYTVLV 117
            + L    T   ED+          V D+    F +D  +G + T   LDRE    Y  +V
Sbjct: 1261 MTLQVRAT--DEDSGLFGQITYSFVNDLGKTKFAVDA-AGIISTLEKLDRENPL-YKDMV 1316

Query: 118  KATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKAT 177
              T  A     R +S  ++ V + D+NDN P+F    Y +S+  +++     ++ +I+A+
Sbjct: 1317 -LTVMALDGGGR-ASFCSVRVILADENDNPPRFRAVEYRMSIKANVA--KGSLVTQIQAS 1372

Query: 178  DADVGANSAIRYAIIGGNTQMQFSIDSLS----GDVSLVKTLDYEQVRSYRLVIRAQDGG 233
            D D G+N  I Y++          +  +S    G +     +D+ Q       ++A D G
Sbjct: 1373 DPDAGSNGRITYSLYSEARLSLVDVLEVSRFYSGWMMTKSNVDHLQGTVLSFFVKATDSG 1432

Query: 234  SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293
            SP++ +     I++   +   P F    +  ++ E+  +G ++  V       G    + 
Sbjct: 1433 SPAKHSLVSAFIHVVPPDAFVPSFSQPQYSFTIPEDTVVGTALGSVYMGPGQTGFFTAVV 1492

Query: 294  YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353
              M D +  G       +D  SG +  S  LD E  + ++  V  T   D   + T    
Sbjct: 1493 GEMVDSNQGGT----FLVDRESGLIRLSKPLDYEEVSIFRFKVAVTTRRDLIEAVTTVDL 1548

Query: 354  XXXXXXXXXXX-XFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRG 410
                         F    Y   + E  P GT VV + A D D   + ++ Y +   ++ G
Sbjct: 1549 EVKILDVNDNNPLFETNTYVATVMEGMPIGTRVVQVRALDPDWGANGQVCY-VEAASSDG 1607

Query: 411  RFSITS----QNGRGLITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDAN 463
              + +S     +  G IT    +D +    Y   V A+D G     S T +V I ++D N
Sbjct: 1608 PITSSSVFAIDSKTGWITTVSEMDHEACSSYSFEVVASDLGELRSLSSTTVVTIAVSDCN 1667

Query: 464  NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQ 522
            +  P FE   Y  +V E   +G  V V+  +D D    N  +++ +S         +   
Sbjct: 1668 DNPPRFERELYRGAVKESDSLGEVVAVLKTSDRDGTDQNRLVSFYISG-------GNPRG 1720

Query: 523  QFVINPQTGA--ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580
             F + P  G   +  + LLDRE    YLL +TA DG   +    T VE++V+D NDN P+
Sbjct: 1721 VFGLAPVQGEWKVYVSGLLDREQQDWYLLNITASDGLYVA---HTAVEVTVMDANDNRPI 1777

Query: 581  FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640
              Q +Y+A+  ED  V   +  V ATDAD G +  I Y L     E+  F +D  +G +R
Sbjct: 1778 CNQAVYSASFPEDIPVNKGILTVAATDADSGSSAEIQYSLFGIGVED--FYMDANTGELR 1835

Query: 641  TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700
            T   +DRE+  ++ L A A DGG     S +   +K+ D+ND+ P F S      + EN+
Sbjct: 1836 TATIMDRETTPSYKLIAQATDGGGLFCRSDI--SLKVLDVNDNAPTFSSPHYLASVYENA 1893

Query: 701  PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760
                 +  ++A DPDEG N  + Y++   D+   FS++   G     +V    LD ES +
Sbjct: 1894 APKALLTRLQASDPDEGLNRTLVYTLDSIDEL--FSIDPVSGM----VVLEKSLDRES-Q 1946

Query: 761  KKYELVIRAASPP-----LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR 815
              Y L ++A         L   V + ILV DVNDNAPV +         +D        R
Sbjct: 1947 DSYRLRVQATDQAGQRGALSTQVNLTILVLDVNDNAPVFQRRDYGVTVPEDVAVGTEVLR 2006

Query: 816  VPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGV 873
            V A   D+    ++ YRI SGN      ++   GS+ ++  L+  V K   + +   DG 
Sbjct: 2007 VLATSVDIGLNAEISYRIRSGNELGKFNIDTNLGSIFVADDLDFEVCKDYYLTIEAWDGG 2066

Query: 874  N 874
            N
Sbjct: 2067 N 2067



 Score =  234 bits (573), Expect = 2e-59
 Identities = 231/823 (28%), Positives = 357/823 (43%), Gaps = 76/823 (9%)

Query: 97  GALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT 156
           G L+    LD E  + Y + V+ TD  +       +TA + + + D NDN P FS+  Y 
Sbjct: 126 GTLIVAKPLDAEVQSVYNMTVQVTDGTN------FATAQVFIRVQDGNDNPPVFSQPAYD 179

Query: 157 VSVDEDISVTDNPVIAKIKATDADVGANSAIR-YAIIGGNTQMQFSIDSLSGDVSLVKTL 215
           VSV EDI V  +  + +++A+D D  A  +   Y  +   +   F ++  +G V     L
Sbjct: 180 VSVSEDIPV--DMELVRVRASDMDERARLSYSIYGSVDPASMRLFRVNPGTGIVYTTDRL 237

Query: 216 DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275
           DYE    + L I  +D   P   +  ++L+ + D NDN P F ++++     E+ P G S
Sbjct: 238 DYEARTQHILTIMVKDQEFPFNRDLARILVAVEDSNDNIPYFTSTVYDAVAYESSPFGTS 297

Query: 276 IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL 335
           +++V A D D G+N +LTYT+      GN      ID  +G ++ +  LD  +   Y L 
Sbjct: 298 VLQVTALDKDNGINGQLTYTIE----AGNTGSVFGIDAATGLIFIARALDLTSVGFYTLT 353

Query: 336 VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395
           V  +D G PP  ATA+              F   +Y+ E+      GT V T+TA     
Sbjct: 354 VRVSDSGFPPLMATASVRISLMLSDYSSPKFSQKEYQAEVL---TTGTHVATVTALSR-- 408

Query: 396 DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMV 455
            + L Y+I+ GN    F I      G+I   + LDF+Q   Y L V A        +  V
Sbjct: 409 -SALFYDISRGNDDLCFYINHHT--GVINTRKLLDFEQTPSYFLVVHALSMTRMEASTTV 465

Query: 456 QINITDANNYAPVFENAPYTASVFEDAPIGTTV-------LVVSATDSDVGINAQITYSL 508
            + + D N+ +PVF+   Y  ++ E AP+ + V       LV+ ATD D   NA + + +
Sbjct: 466 TVQVGDVNDNSPVFQQLRYVGTISEAAPVNSVVLGDDGNPLVIQATDMDRNHNALLVFHI 525

Query: 509 SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP--SLSDTTD 566
             E +          F I+  TG+I T   LD E  S +   V  RD G P  S     D
Sbjct: 526 LDETAR-------MFFSIDSGTGSIRTIASLDYEIFSEFFFQVYVRDSGQPPRSADSPAD 578

Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV-------GLNGRIHYE 619
           V I V+++ND+ P   Q  Y   ++     G  V QV A+D D+        +  ++ Y 
Sbjct: 579 VFIKVININDSPPKLSQDTYETVLLLPTYAGVEVLQVEASDPDMTSDFTLKSVTPQLVYS 638

Query: 620 LDPKDREEGSFVIDPASGVIR-TNKALDRESVATHDLKAVAIDGG-TPPQSSTVIVHIKI 677
           L   + E  +F +D  SG +   N  L+++    +       DG  T   S TV+V   I
Sbjct: 639 LVESNVE--NFSVDRFSGTVTVANPNLNKD---RYQFTVKVWDGRFTSMASVTVLVRKAI 693

Query: 678 ED--INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735
           +   +  SP  F S  +   IS N  + T +  I  H  +E     + Y++    +   F
Sbjct: 694 DSGLLYTSPEYFAS--IPENIS-NVTVVTVVSTI-GHRLNE----PLRYTLLNAGE--RF 743

Query: 736 SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP---LWNDVRVEILVTDVNDNAP 792
            +    G     L T V  D E     YELV+  +          V V++ V DVNDNAP
Sbjct: 744 VIRPTCG---VVLTTGVPFDREL-ADSYELVVEVSREDEILRVARVTVQVQVEDVNDNAP 799

Query: 793 VMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMT 850
              +         D  P     +V A D D  V  ++ Y  L   + N   +N  TG +T
Sbjct: 800 EFVNLPYYAAVQVDAEPESAIFKVSAVDRDTGVNGEVSYS-LKQQHRN-FQMNPVTGELT 857

Query: 851 LSPQLNTNVPKLATMEVSV-TD-GVNEIKAMMQLSVRLITEEM 891
           L     +++       V V TD G   +   ++L V ++ + M
Sbjct: 858 LKKAFESDLSNAEYKLVLVATDGGFPPLSREVELPVTVVNKAM 900



 Score =  213 bits (519), Expect = 8e-53
 Identities = 196/701 (27%), Positives = 319/701 (45%), Gaps = 48/701 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V++ ND  P      YE  +     +G  VL ++A+D D+      ++T++ VT   +
Sbjct: 581  IKVININDSPPKLSQDTYETVLLLPTYAGVEVLQVEASDPDMTS----DFTLKSVTPQLV 636

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           V++ F +D  SG  +T A+ +  K  RY   VK  D       R 
Sbjct: 637  --------YSLVESNVEN-FSVDRFSGT-VTVANPNLNK-DRYQFTVKVWD------GRF 679

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +S A++ V +    D+   ++   Y  S+ E+IS   N  +  + +T      N  +RY 
Sbjct: 680  TSMASVTVLVRKAIDSGLLYTSPEYFASIPENIS---NVTVVTVVSTIGH-RLNEPLRYT 735

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            ++  N   +F I    G V       D E   SY LV+         R     + + + D
Sbjct: 736  LL--NAGERFVIRPTCGVVLTTGVPFDRELADSYELVVEVSREDEILRVARVTVQVQVED 793

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            VNDNAP F    +  +V  +     +I +V A D D GVN E++Y++  +     ++ P+
Sbjct: 794  VNDNAPEFVNLPYYAAVQVDAEPESAIFKVSAVDRDTGVNGEVSYSLKQQHRNFQMN-PV 852

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            T +      + S      + A+Y+L++ ATDGG PP S                  F   
Sbjct: 853  TGELTLKKAFESDL----SNAEYKLVLVATDGGFPPLSREV--ELPVTVVNKAMPVFDKP 906

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
             Y V + ED    T ++ + A+ + E   + + I  G+   +F I      G I+V  PL
Sbjct: 907  FYGVTVREDVAVSTSILGINAS-SPEGQIVIFTIIDGDPSFQFDIGFDT--GTISVIYPL 963

Query: 430  DFKQERRYVLTVSATDS-GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
            D++  + Y LTV ATD+  G      V + + D N+ AP+F+N  Y++ + E+  IGTTV
Sbjct: 964  DYETTQYYRLTVKATDTQTGAKSEVDVDVVVLDVNDNAPLFQNTSYSSVLPENVMIGTTV 1023

Query: 489  LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
            L V A D D   NA ++Y + S+I N         F I+  +G I   + LD E +  + 
Sbjct: 1024 LKVFAQDQDSEKNAIVSYQILSDIYNST-----DYFHIDSSSGLIFMARRLDYELVQRHN 1078

Query: 549  LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
              V A D G P+LS    V ++V D NDN P F Q LY A + E A     V+ V A+DA
Sbjct: 1079 FIVRATDSGDPTLSSDVSVTVTVTDTNDNPPNFSQTLYEAFVSELAPRDHFVTCVQASDA 1138

Query: 609  DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
            D+    R+ Y +     E  +F+++P +GV+R +    +    ++ L  V++  G    +
Sbjct: 1139 DICDAQRLRYSI-VSGNERMTFLMEPDTGVLRLSNKRRQGMKLSYQLN-VSVSDGVFTNT 1196

Query: 669  STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
            + VIV  ++   N   PVF        + EN+P G+ + ++
Sbjct: 1197 AQVIV--QVLGANLYSPVFSQRFYLAEVQENAPPGSKVIQV 1235



 Score =  209 bits (510), Expect = 1e-51
 Identities = 204/793 (25%), Positives = 347/793 (43%), Gaps = 57/793 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V D ND+SPVF+  +Y  ++ E A   + VL       D G    ++ T      D  
Sbjct: 467  VQVGDVNDNSPVFQQLRYVGTISEAAPVNSVVLG------DDGNPLVIQAT------DMD 514

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
               +A           +  F ID  +G++ T ASLD E  + +   V   D   P     
Sbjct: 515  RNHNALLVFHILDETARMFFSIDSGTGSIRTIASLDYEIFSEFFFQVYVRDSGQPPRSA- 573

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTY-TVSVDEDISVTDNPVIAKIKATDADVGANSAIR- 188
             S A + + +I+ ND+ P+ S+ TY TV +    +  +   + +++A+D D+ ++  ++ 
Sbjct: 574  DSPADVFIKVININDSPPKLSQDTYETVLLLPTYAGVE---VLQVEASDPDMTSDFTLKS 630

Query: 189  ------YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
                  Y+++  N +  FS+D  SG V++    +  + R Y+  ++  DG   S ++ T 
Sbjct: 631  VTPQLVYSLVESNVE-NFSVDRFSGTVTVANP-NLNKDR-YQFTVKVWDGRFTSMASVTV 687

Query: 243  LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
            L   +R   D+   + +  +  S+ EN+    ++V V +      +N  L YT+      
Sbjct: 688  L---VRKAIDSGLLYTSPEYFASIPENIS-NVTVVTVVS-TIGHRLNEPLRYTLL----- 737

Query: 303  GNVDLPITIDPRSGWVYTSG-QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
             N      I P  G V T+G   DRE    Y+L+V  +   +  R A  T          
Sbjct: 738  -NAGERFVIRPTCGVVLTTGVPFDRELADSYELVVEVSREDEILRVARVTVQVQVEDVND 796

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421
                F+   Y   +  D  P + +  ++A D D         +       F +    G  
Sbjct: 797  NAPEFVNLPYYAAVQVDAEPESAIFKVSAVDRDTGVNGEVSYSLKQQHRNFQMNPVTGEL 856

Query: 422  LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
             +  A   D      Y L + ATD G    +  V++ +T  N   PVF+   Y  +V ED
Sbjct: 857  TLKKAFESDLSNAE-YKLVLVATDGGFPPLSREVELPVTVVNKAMPVFDKPFYGVTVRED 915

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
              + T++L ++A+  +  I   + +++   I  +       QF I   TG I+    LD 
Sbjct: 916  VAVSTSILGINASSPEGQI---VIFTI---IDGDP----SFQFDIGFDTGTISVIYPLDY 965

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
            ET   Y LTV A D    + S+  DV++ V+DVNDN P+F+   Y++ + E+ ++GT+V 
Sbjct: 966  ETTQYYRLTVKATDTQTGAKSEV-DVDVVVLDVNDNAPLFQNTSYSSVLPENVMIGTTVL 1024

Query: 602  QVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
            +V A D D   N  + Y+ L         F ID +SG+I   + LD E V  H+    A 
Sbjct: 1025 KVFAQDQDSEKNAIVSYQILSDIYNSTDYFHIDSSSGLIFMARRLDYELVQRHNFIVRAT 1084

Query: 661  DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
            D G P  SS V V + + D ND+PP F       ++SE +P    +  ++A D D     
Sbjct: 1085 DSGDPTLSSDVSVTVTVTDTNDNPPNFSQTLYEAFVSELAPRDHFVTCVQASDADICDAQ 1144

Query: 721  VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRV 780
             + YSI  G++  +F +E   G     ++ + +   +  +  Y+L +  +     N  +V
Sbjct: 1145 RLRYSIVSGNERMTFLMEPDTG-----VLRLSNKRRQGMKLSYQLNVSVSDGVFTNTAQV 1199

Query: 781  EILVTDVNDNAPV 793
             + V   N  +PV
Sbjct: 1200 IVQVLGANLYSPV 1212



 Score =  204 bits (499), Expect = 2e-50
 Identities = 174/550 (31%), Positives = 246/550 (44%), Gaps = 41/550 (7%)

Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239
           D GA          G+  MQF +    G + + K LD E    Y + ++  DG   +   
Sbjct: 99  DTGAQQHPHINDAAGSFDMQFDLQVGVGTLIVAKPLDAEVQSVYNMTVQVTDG---TNFA 155

Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
           T Q+ I ++D NDN P F    +  SVSE++P+   +VRV+A D DE   A L+Y++   
Sbjct: 156 TAQVFIRVQDGNDNPPVFSQPAYDVSVSEDIPVDMELVRVRASDMDE--RARLSYSIYGS 213

Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
               ++ L   ++P +G VYT+ +LD E + ++ L +   D   P     A         
Sbjct: 214 VDPASMRL-FRVNPGTGIVYTTDRLDYEARTQHILTIMVKDQEFPFNRDLARILVAVEDS 272

Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQ 417
                 F    Y+    E  P GT V+ +TA D D   + +L Y I  GNT   F I + 
Sbjct: 273 NDNIPYFTSTVYDAVAYESSPFGTSVLQVTALDKDNGINGQLTYTIEAGNTGSVFGIDA- 331

Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYT 475
              GLI +A+ LD      Y LTV  +DSG      TA V+I++  ++  +P F    Y 
Sbjct: 332 -ATGLIFIARALDLTSVGFYTLTVRVSDSGFPPLMATASVRISLMLSDYSSPKFSQKEYQ 390

Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
           A V      GT V  V+A        + + Y +S         + D  F IN  TG I T
Sbjct: 391 AEVL---TTGTHVATVTALS-----RSALFYDISR-------GNDDLCFYINHHTGVINT 435

Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
            KLLD E    Y L V A    +  +  +T V + V DVNDN PVF+Q  Y   I E A 
Sbjct: 436 RKLLDFEQTPSYFLVVHAL--SMTRMEASTTVTVQVGDVNDNSPVFQQLRYVGTISEAAP 493

Query: 596 VGTSV-------SQVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGVIRTNKALDR 647
           V + V         + ATD D   N  + +  LD   R    F ID  +G IRT  +LD 
Sbjct: 494 VNSVVLGDDGNPLVIQATDMDRNHNALLVFHILDETARM--FFSIDSGTGSIRTIASLDY 551

Query: 648 ESVATHDLKAVAIDGGTPPQS--STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
           E  +    +    D G PP+S  S   V IK+ +INDSPP    D     +   +  G  
Sbjct: 552 EIFSEFFFQVYVRDSGQPPRSADSPADVFIKVININDSPPKLSQDTYETVLLLPTYAGVE 611

Query: 706 IGEIRAHDPD 715
           + ++ A DPD
Sbjct: 612 VLQVEASDPD 621



 Score =  181 bits (440), Expect = 3e-43
 Identities = 142/486 (29%), Positives = 233/486 (47%), Gaps = 40/486 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            Q+ V D ND++P F    Y A+V+  A   + +  + A D+D G N EV Y+++    + 
Sbjct: 788  QVQVEDVNDNAPEFVNLPYYAAVQVDAEPESAIFKVSAVDRDTGVNGEVSYSLKQQHRN- 846

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDRE-KVARYTVLVKATDQASPVSD 128
                                F+++  +G L  + + + +   A Y +++ ATD   P   
Sbjct: 847  --------------------FQMNPVTGELTLKKAFESDLSNAEYKLVLVATDGGFPP-- 884

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             LS    + V ++  N   P F +  Y V+V ED++V+ +  I  I A+  +      + 
Sbjct: 885  -LSREVELPVTVV--NKAMPVFDKPFYGVTVREDVAVSTS--ILGINASSPE---GQIVI 936

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            + II G+   QF I   +G +S++  LDYE  + YRL ++A D  + ++S     ++ + 
Sbjct: 937  FTIIDGDPSFQFDIGFDTGTISVIYPLDYETTQYYRLTVKATDTQTGAKSEVDVDVV-VL 995

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            DVNDNAP F  + +   + ENV IG ++++V A D D   NA ++Y +    Y  + D  
Sbjct: 996  DVNDNAPLFQNTSYSSVLPENVMIGTTVLKVFAQDQDSEKNAIVSYQILSDIYN-STDY- 1053

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
              ID  SG ++ + +LD E   ++  +V ATD GDP  S+  +              F  
Sbjct: 1054 FHIDSSSGLIFMARRLDYELVQRHNFIVRATDSGDPTLSSDVSVTVTVTDTNDNPPNFSQ 1113

Query: 369  GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
              YE  ++E  P    V  + A+DAD  +  RL Y I  GN R  F +    G  ++ ++
Sbjct: 1114 TLYEAFVSELAPRDHFVTCVQASDADICDAQRLRYSIVSGNERMTFLMEPDTG--VLRLS 1171

Query: 427  QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
                   +  Y L VS +D G  ++TA V + +  AN Y+PVF    Y A V E+AP G+
Sbjct: 1172 NKRRQGMKLSYQLNVSVSD-GVFTNTAQVIVQVLGANLYSPVFSQRFYLAEVQENAPPGS 1230

Query: 487  TVLVVS 492
             V+ VS
Sbjct: 1231 KVIQVS 1236



 Score =  169 bits (410), Expect = 1e-39
 Identities = 132/416 (31%), Positives = 196/416 (47%), Gaps = 26/416 (6%)

Query: 387 TLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446
           T+ A D       H     G+   +F +  Q G G + VA+PLD + +  Y +TV  TD 
Sbjct: 94  TVEADDTGAQQHPHINDAAGSFDMQFDL--QVGVGTLIVAKPLDAEVQSVYNMTVQVTD- 150

Query: 447 GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506
           G    TA V I + D N+  PVF    Y  SV ED P+   ++ V A+D D    A+++Y
Sbjct: 151 GTNFATAQVFIRVQDGNDNPPVFSQPAYDVSVSEDIPVDMELVRVRASDMDE--RARLSY 208

Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566
           S+   +   ++    + F +NP TG + T   LD E  + ++LT+  +D   P   D   
Sbjct: 209 SIYGSVDPASM----RLFRVNPGTGIVYTTDRLDYEARTQHILTIMVKDQEFPFNRDLAR 264

Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE 626
           + ++V D NDN P F   +Y A   E +  GTSV QV A D D G+NG++ Y ++  +  
Sbjct: 265 ILVAVEDSNDNIPYFTSTVYDAVAYESSPFGTSVLQVTALDKDNGINGQLTYTIEAGN-- 322

Query: 627 EGS-FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685
            GS F ID A+G+I   +ALD  SV  + L     D G PP  +T  V I +   + S P
Sbjct: 323 TGSVFGIDAATGLIFIARALDLTSVGFYTLTVRVSDSGFPPLMATASVRISLMLSDYSSP 382

Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745
            F       Y +E    GT +  + A        + + Y I  G+D   F +    G   
Sbjct: 383 KFSQ---KEYQAEVLTTGTHVATVTALS-----RSALFYDISRGNDDLCFYINHHTG--- 431

Query: 746 AELVTMVDLDYESPRKKYELVIRAAS-PPLWNDVRVEILVTDVNDNAPVMKDFQII 800
             + T   LD+E     Y LV+ A S   +     V + V DVNDN+PV +  + +
Sbjct: 432 -VINTRKLLDFEQ-TPSYFLVVHALSMTRMEASTTVTVQVGDVNDNSPVFQQLRYV 485



 Score =  150 bits (364), Expect = 5e-34
 Identities = 124/436 (28%), Positives = 203/436 (46%), Gaps = 50/436 (11%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            ++  I VLD ND++PVF+ + Y  +V E  + GT VL + AT  DIG NAE+ Y I   +
Sbjct: 1969 VNLTILVLDVNDNAPVFQRRDYGVTVPEDVAVGTEVLRVLATSVDIGLNAEISYRIR--S 2026

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
             + L                   F ID   G++     LD E    Y + ++A D  +P 
Sbjct: 2027 GNELGK-----------------FNIDTNLGSIFVADDLDFEVCKDYYLTIEAWDGGNP- 2068

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
               LSS   + ++++D NDN P FS+  Y V V ED SV    ++ ++ A D D   N  
Sbjct: 2069 --PLSSATVVTIDLMDVNDNAPTFSQDIYNVLVSEDASV--GQMVTRVSAEDLDSQGNGR 2124

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            I Y+I+ G+    F ID ++G + + K LD E V  Y L ++A D GSP+ S+T  L I+
Sbjct: 2125 ITYSILKGDRNNHFWIDPVTGILKVNKRLDRELVSRYSLSVQAFDSGSPAMSSTVTLNID 2184

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY----------DADEGVNAE-LTYT 295
            I D+NDN+P F        +    P    +V V++Y            ++   +  L  +
Sbjct: 2185 ISDINDNSPVFTPPNSTAIIQVPAP-ALLLVFVRSYISLPPPLSHLQLNQAAGSTLLKLS 2243

Query: 296  MTDKD------------YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD 343
            ++DKD             +GN +   ++D ++G + ++   D E   ++ L +  +D G 
Sbjct: 2244 VSDKDSPKNGPPFDFRIVSGNEENFFSLD-QAGTLKSNRVFDPEAPREFTLEIQVSDSGK 2302

Query: 344  PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEI 403
            P  +A++                 P +  + +A D  PG P+  + ATD D ++ L +  
Sbjct: 2303 PRLAASSWVFLRVIGNSQYKPLVSPLEIFIVMATDTFPGGPIGRIYATDRDPNDVLSF-T 2361

Query: 404  TGGNTRGRFSITSQNG 419
                ++  F I  Q+G
Sbjct: 2362 QKLQSKSMFKINRQDG 2377



 Score = 77.8 bits (183), Expect = 4e-12
 Identities = 71/270 (26%), Positives = 121/270 (44%), Gaps = 19/270 (7%)

Query: 630 FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES 689
           F +    G +   K LD E  + +++     DG      +T  V I+++D ND+PPVF  
Sbjct: 119 FDLQVGVGTLIVAKPLDAEVQSVYNMTVQVTDG---TNFATAQVFIRVQDGNDNPPVFSQ 175

Query: 690 DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV 749
                 +SE+ P+   +  +RA D DE   A + YSI G  D  S  L  R       + 
Sbjct: 176 PAYDVSVSEDIPVDMELVRVRASDMDE--RARLSYSIYGSVDPASMRL-FRVNPGTGIVY 232

Query: 750 TMVDLDYESPRKKY-ELVIRAASPPLWNDV-RVEILVTDVNDNAPVMKDFQIIFNNYKDC 807
           T   LDYE+  +    ++++    P   D+ R+ + V D NDN P       +++     
Sbjct: 233 TTDRLDYEARTQHILTIMVKDQEFPFNRDLARILVAVEDSNDNIPYFTS--TVYDAV--A 288

Query: 808 FPVGPFG----RVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPK 861
           +   PFG    +V A D D  +  +L Y I +GN  ++  ++  TG + ++  L+     
Sbjct: 289 YESSPFGTSVLQVTALDKDNGINGQLTYTIEAGNTGSVFGIDAATGLIFIARALDLTSVG 348

Query: 862 LATMEVSVTD-GVNEIKAMMQLSVRLITEE 890
             T+ V V+D G   + A   + + L+  +
Sbjct: 349 FYTLTVRVSDSGFPPLMATASVRISLMLSD 378



 Score = 40.7 bits (91), Expect = 0.57
 Identities = 15/43 (34%), Positives = 22/43 (51%)

Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            T A C  + + C   PC NG +C  +   ++C C +G TG  C
Sbjct: 2887 TGARCEVELTSCMPDPCQNGGDCKPVGSAFLCSCPQGLTGLIC 2929



 Score = 38.3 bits (85), Expect = 3.0
 Identities = 12/39 (30%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C +  + C  + C NG EC + + ++ C+C +G  G  C
Sbjct: 2929 CDQDVNECEHSECGNGGECVNTFGSFFCNCSQGSEGPFC 2967


>UniRef50_A7T100 Cluster: Predicted protein; n=1; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 2058

 Score =  385 bits (947), Expect = e-104
 Identities = 274/869 (31%), Positives = 429/869 (49%), Gaps = 60/869 (6%)

Query: 17   NDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAX 76
            ND SP+FE   Y  +V E AS G  +  + ATD+D G NA + Y+         N  +A 
Sbjct: 1083 NDESPLFEKSMYYVNVSESASRGIVIGRVTATDRDEGINAIIFYSS--------NGAEAK 1134

Query: 77   XXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATI 136
                         F +   +G ++  + LDRE    Y + V A +  +   D   +T  +
Sbjct: 1135 -------------FYVSRSTGDIIVDSPLDREFKNVYILNVTAANIVAGAQD---TTTQV 1178

Query: 137  HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNT 196
            H+ + D  D+ P F+  + TV + E+ S+  N  + KI A D D+G    I Y+I  G+ 
Sbjct: 1179 HITVTDVIDDKPYFNSSSLTVKLSENASIGTN--VTKITALDKDIG--DTISYSIANGDP 1234

Query: 197  QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256
               F+ID+++G++  V  LD E V  Y L ++A+D  +   S+  ++++ + DVNDN P 
Sbjct: 1235 YGLFTIDNVTGEIRTVAELDRENVTQYELFVQAKDSVN-LVSDLLKVVVQVEDVNDNPPV 1293

Query: 257  FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316
            F    +     E  P G SI++V+A DAD G NA + Y++ +     NV   +T++  +G
Sbjct: 1294 FSMPGYTIEYWEESPEGTSILQVKAIDADIGDNAAVLYSIVE-----NVTDYVTVNAITG 1348

Query: 317  WV-YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375
             +   S QLDRE +  +   + ATD G P +S+TA+              F    Y   +
Sbjct: 1349 VISLGSSQLDREVEEYFNFTIRATDSGVPSKSSTASVAIKLVDINDNSPVFNNTDYYAYV 1408

Query: 376  AEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ 433
             E++P GTPV+ +TA+D D   + +L Y +  G    RF+I    G   IT  +PL+ ++
Sbjct: 1409 RENQPAGTPVLVVTASDKDVGTNAKLSY-VLSGVLYTRFAIDPDTGN--ITTREPLNREE 1465

Query: 434  ERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491
               Y LT+ A DS    R  T  V I +TDAN++ P F  + Y  SV ED  +G TV  V
Sbjct: 1466 TGSYTLTLRAVDSAIRAREGTTRVIITVTDANDHVPQFTQSGYAFSVREDVKVGHTVGRV 1525

Query: 492  SATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTV 551
            + TD D+  NA++ Y +SS   N ++      F +N  TG I+T   LDRE  + Y L +
Sbjct: 1526 ATTDEDINDNARVRYYISS--GNTSL-----MFSVNETTGIISTTSTLDREQNASYTLII 1578

Query: 552  TARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG 611
            TA+D G+P+L   T V I++ DVNDN+P+F + +Y   + E   + T V QV ATD D G
Sbjct: 1579 TAKDHGIPALESNTSVMITIEDVNDNKPLFSKSVYNVTLRESVFLKTQVVQVIATDPDEG 1638

Query: 612  LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671
             NG+  Y++   D ++  F ID  +G+I     LD E  + ++L   A D GTPP +   
Sbjct: 1639 ANGQFTYKITAGDTDD-VFYIDANTGLITIKAKLDYEKTSLYNLTVSAQDLGTPPLTGAC 1697

Query: 672  IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGD 730
             V I + D++D+ PVF     +  + EN   G  +  + A D D E  +  V+Y I+ G+
Sbjct: 1698 FVEIHVSDVDDNAPVFHKPRYSAELYENVTRGHHVITVNATDIDAEASHKRVYYRIESGN 1757

Query: 731  DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND----VRVEILVTD 786
              + F +  + G           L+ E+   +YEL + A S     +    V   I V D
Sbjct: 1758 TDSMFLIGEQSGVITLNCTPSGCLNRET-HARYELQVAAISRVNLTEQKSLVPAVITVLD 1816

Query: 787  VNDNAPVMKDFQIIFNNYKDCFPV--GPFGRVPAYDAD--VTDKLQYRILSGNNANLILL 842
            VNDNAP       + +  +D  P+       V A D D   + ++ + I+SGN   +  +
Sbjct: 1817 VNDNAPRFDSESYVRSVLEDTGPITDATILTVKAQDGDEGESGEIIFTIVSGNENGVFQM 1876

Query: 843  NETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            +  TG +T +  L+       ++ V   D
Sbjct: 1877 DNKTGVLTRTRPLDREDTSFYSLVVMAED 1905



 Score =  364 bits (895), Expect = 2e-98
 Identities = 279/863 (32%), Positives = 406/863 (47%), Gaps = 72/863 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D  D  P F        + E AS GT V  + A D+DIG    + Y+I     D  
Sbjct: 1180 ITVTDVIDDKPYFNSSSLTVKLSENASIGTNVTKITALDKDIGDT--ISYSI--ANGDPY 1235

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                              +F ID  +G + T A LDRE V +Y + V+A D  + VSD L
Sbjct: 1236 G-----------------LFTIDNVTGEIRTVAELDRENVTQYELFVQAKDSVNLVSDLL 1278

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
                 + V + D NDN P FS   YT+   E+    +   I ++KA DAD+G N+A+ Y+
Sbjct: 1279 K----VVVQVEDVNDNPPVFSMPGYTIEYWEE--SPEGTSILQVKAIDADIGDNAAVLYS 1332

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            I+  N     ++++++G +SL  + LD E    +   IRA D G PS+S+T  + I + D
Sbjct: 1333 IV-ENVTDYVTVNAITGVISLGSSQLDREVEEYFNFTIRATDSGVPSKSSTASVAIKLVD 1391

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            +NDN+P F  + +   V EN P G  ++ V A D D G NA+L+Y ++   YT       
Sbjct: 1392 INDNSPVFNNTDYYAYVRENQPAGTPVLVVTASDKDVGTNAKLSYVLSGVLYT-----RF 1446

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             IDP +G + T   L+RE    Y L + A D     R  T                F   
Sbjct: 1447 AIDPDTGNITTREPLNREETGSYTLTLRAVDSAIRAREGTTRVIITVTDANDHVPQFTQS 1506

Query: 370  QYEVELAEDEPPGTPVVTLTATDAD-EDN-RLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
             Y   + ED   G  V  +  TD D  DN R+ Y I+ GNT   FS+      G+I+   
Sbjct: 1507 GYAFSVREDVKVGHTVGRVATTDEDINDNARVRYYISSGNTSLMFSVNETT--GIISTTS 1564

Query: 428  PLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
             LD +Q   Y L ++A D G         V I I D N+  P+F  + Y  ++ E   + 
Sbjct: 1565 TLDREQNASYTLIITAKDHGIPALESNTSVMITIEDVNDNKPLFSKSVYNVTLRESVFLK 1624

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
            T V+ V ATD D G N Q TY +++          D  F I+  TG IT    LD E  S
Sbjct: 1625 TQVVQVIATDPDEGANGQFTYKITA-------GDTDDVFYIDANTGLITIKAKLDYEKTS 1677

Query: 546  GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
             Y LTV+A+D G P L+    VEI V DV+DN PVF +  Y+A + E+   G  V  V A
Sbjct: 1678 LYNLTVSAQDLGTPPLTGACFVEIHVSDVDDNAPVFHKPRYSAELYENVTRGHHVITVNA 1737

Query: 606  TDADV-GLNGRIHYELDPKDREEGSFVIDPASGVIRTN----KALDRESVATHDLKAVAI 660
            TD D    + R++Y ++     +  F+I   SGVI  N      L+RE+ A ++L+  AI
Sbjct: 1738 TDIDAEASHKRVYYRIE-SGNTDSMFLIGEQSGVITLNCTPSGCLNRETHARYELQVAAI 1796

Query: 661  DG-GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS-PI-GTTIGEIRAHDPDEG 717
                   Q S V   I + D+ND+ P F+S+     + E++ PI   TI  ++A D DEG
Sbjct: 1797 SRVNLTEQKSLVPAVITVLDVNDNAPRFDSESYVRSVLEDTGPITDATILTVKAQDGDEG 1856

Query: 718  PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPL 774
             +  + ++I  G+++  F ++ + G     L     LD E     Y LV+ A     P L
Sbjct: 1857 ESGEIIFTIVSGNENGVFQMDNKTG----VLTRTRPLDRED-TSFYSLVVMAEDKGEPAL 1911

Query: 775  WNDVRVEILVTDVNDNAPVMK-DFQIIFNNYKDCFPVG-------PFGRVPAYDADVTDK 826
             + V V I V D+NDN P+++    ++    +  F V        P G V A D D  + 
Sbjct: 1912 SSSVTVNITVLDMNDNLPILQTPMDVLIPERRTTFSVKENLDAGVPVGVVAAQDLDTKNL 1971

Query: 827  LQYRILSGNNANLILLNETTGSM 849
            + Y I +       +LNET+G +
Sbjct: 1972 IYYYITNTEEQKYFILNETSGEL 1994



 Score =  339 bits (834), Expect = 5e-91
 Identities = 249/785 (31%), Positives = 387/785 (49%), Gaps = 68/785 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V D ND+ PVF M  Y     E +  GT++L +KA D DIG NA V Y+I        
Sbjct: 1282 VQVEDVNDNPPVFSMPGYTIEYWEESPEGTSILQVKAIDADIGDNAAVLYSI-------- 1333

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLVKATDQASPVSDR 129
                           V D   ++  +G + L  + LDRE    +   ++ATD   P    
Sbjct: 1334 ------------VENVTDYVTVNAITGVISLGSSQLDREVEEYFNFTIRATDSGVPSK-- 1379

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             SSTA++ + ++D NDN P F+   Y   V E+      PV+  + A+D DVG N+ + Y
Sbjct: 1380 -SSTASVAIKLVDINDNSPVFNNTDYYAYVREN-QPAGTPVLV-VTASDKDVGTNAKLSY 1436

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             ++ G    +F+ID  +G+++  + L+ E+  SY L +RA D    +R  TT+++I + D
Sbjct: 1437 -VLSGVLYTRFAIDPDTGNITTREPLNREETGSYTLTLRAVDSAIRAREGTTRVIITVTD 1495

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
             ND+ P+F  S +  SV E+V +G+++ RV   D D   NA + Y ++    +GN  L  
Sbjct: 1496 ANDHVPQFTQSGYAFSVREDVKVGHTVGRVATTDEDINDNARVRYYIS----SGNTSLMF 1551

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            +++  +G + T+  LDRE  A Y L++TA D G P   +  +              F   
Sbjct: 1552 SVNETTGIISTTSTLDREQNASYTLIITAKDHGIPALESNTSVMITIEDVNDNKPLFSKS 1611

Query: 370  QYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
             Y V L E     T VV + ATD DE  + +  Y+IT G+T   F I +  G  LIT+  
Sbjct: 1612 VYNVTLRESVFLKTQVVQVIATDPDEGANGQFTYKITAGDTDDVFYIDANTG--LITIKA 1669

Query: 428  PLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTASVFEDAPIG 485
             LD+++   Y LTVSA D G    T    V+I+++D ++ APVF    Y+A ++E+   G
Sbjct: 1670 KLDYEKTSLYNLTVSAQDLGTPPLTGACFVEIHVSDVDDNAPVFHKPRYSAELYENVTRG 1729

Query: 486  TTVLVVSATDSDV-GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN----KLLD 540
              V+ V+ATD D    + ++ Y + S        + D  F+I  Q+G IT N      L+
Sbjct: 1730 HHVITVNATDIDAEASHKRVYYRIES-------GNTDSMFLIGEQSGVITLNCTPSGCLN 1782

Query: 541  RETMSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA--LVG 597
            RET + Y L V A     +          I+V+DVNDN P F  + Y  +++ED   +  
Sbjct: 1783 RETHARYELQVAAISRVNLTEQKSLVPAVITVLDVNDNAPRFDSESYVRSVLEDTGPITD 1842

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
             ++  V A D D G +G I + +     E G F +D  +GV+   + LDRE  + + L  
Sbjct: 1843 ATILTVKAQDGDEGESGEIIFTI-VSGNENGVFQMDNKTGVLTRTRPLDREDTSFYSLVV 1901

Query: 658  VAIDGGTPPQSSTVIVHIKIEDINDSPPVFES--DCL------TFYISENSPIGTTIGEI 709
            +A D G P  SS+V V+I + D+ND+ P+ ++  D L      TF + EN   G  +G +
Sbjct: 1902 MAEDKGEPALSSSVTVNITVLDMNDNLPILQTPMDVLIPERRTTFSVKENLDAGVPVGVV 1961

Query: 710  RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
             A D D     +++Y I   ++   F L    G    EL T + LD E     Y L ++A
Sbjct: 1962 AAQDLD--TKNLIYYYITNTEEQKYFILNETSG----ELRTRITLDREDSSVHY-LYVKA 2014

Query: 770  ASPPL 774
            ++  L
Sbjct: 2015 SNDKL 2019



 Score =  326 bits (802), Expect = 4e-87
 Identities = 270/880 (30%), Positives = 416/880 (47%), Gaps = 106/880 (12%)

Query: 15  DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
           D ND++PVF  Q Y A + E A  GTT+L + A D D G N++V+Y     TA T  P  
Sbjct: 38  DYNDNAPVFTEQPYMAKIAENARVGTTILKISAIDADSGTNSQVQYKFSNATA-TQTP-- 94

Query: 75  AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134
                          F ++  +G L     LD E    Y ++V A D   P   +L S  
Sbjct: 95  --------------FFSLNSVNGELTLGGPLDFEVARSYMLVVIAEDLGVP---KLESRT 137

Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194
           T+ + + D +D  P+F +  Y   ++E+  +     +  ++A D DVG N+ I Y II G
Sbjct: 138 TVIIEVTDISDMPPRFLQSFYLKEIEENTPI--GSTVVTVEARDGDVGINNPILYEIISG 195

Query: 195 NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNA 254
           N+   F+IDS +G +++  ++D E+   +R+ ++A +   P+ + T  +++ + DVNDN 
Sbjct: 196 NSDGVFTIDSNTGVITVNGSIDAEKTDVFRITVKASEVPDPNSNTTVTVVVTVVDVNDNR 255

Query: 255 PRFYTSLFQESVSENVPIGYSIV--RVQAYDADEG-VNAELTYTMTDKDYTGNVDLPITI 311
           P F  S++   V E+V +   +V  ++Q  D D+  V   + Y +   D          I
Sbjct: 256 PAFLQSVYIFDVREDVALPGRVVSDQLQVTDGDKNPVFRRVLYHLVGADSD-----KFAI 310

Query: 312 DPRSGWVYTSGQLDRETQAKY-------------------------QLLVTATDGGDPPR 346
           DP SG +Y +  LD E Q  +                         +++ T TD  +   
Sbjct: 311 DPTSGTLYINKTLDYEKQINFTFDWERGCGSGGGSGWDWTGRGEEKKVVATETDTSE-KF 369

Query: 347 SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEIT 404
           SA A+              F    Y   + E+  PGT +  +TATDAD      L YE+ 
Sbjct: 370 SANASVTLTLINVNDNKPMFAKSSYNYTMDEEITPGTHIADITATDADLGTFGALTYELR 429

Query: 405 GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITD 461
           GG     FS+ + N  G I+ AQ LD+   R+Y  ++   D GG       A V + + D
Sbjct: 430 GGQA-AYFSVNADN--GTISAAQILDYDTLRQYQFSLVVKDGGGFYQEIAIATVTVTLQD 486

Query: 462 ANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521
            N+  P F   PYT+ + E+ P GT V  V+ATD D G N ++++++S   + +   H  
Sbjct: 487 VNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNIS---AGDDGGH-- 541

Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581
             F IN  +G +TT + LDRET++ Y LTV+A D GV S      + ++V+D NDN P  
Sbjct: 542 --FSIN-GSGLVTTARELDRETIATYTLTVSAYDHGVSSRHKHVQLTVNVLDENDNTPQI 598

Query: 582 KQQL-YTANIMEDALVGT-SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639
              L  T NI E A  GT  +S + A D D G NG++ Y +   D     F ++ A+G +
Sbjct: 599 TDGLTITTNISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGGD---SRFTLNSATGRL 655

Query: 640 RTN-KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE----SDCLTF 694
           + +   LDRE   ++DL     D G+PP +++  VH+ I D+ND+ P F+        T+
Sbjct: 656 QISPTGLDRELKDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTPAFDPNPAQSLATY 715

Query: 695 YISENSPIGT---TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751
            I+ +   GT   T+ +I A DPD   N  V YS+  GD+   F L+   G    EL   
Sbjct: 716 VITVDEGPGTINKTLIDINATDPDADANGKVAYSL-SGDEHGFFRLDPVTG----ELSVR 770

Query: 752 VDLDYESPRK--------KYELVIRAA--SPPLWN----DVRVEILVTDVNDNAPVMKDF 797
            +LD ESP+         ++ L I A   + P+ +     VRV I V D NDN+P  +  
Sbjct: 771 KELDRESPQMSRNAQGDGRFLLDITATDQATPISDRKSATVRVSITVRDTNDNSPQFQSQ 830

Query: 798 QIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGN 835
                  +   P     +V A D D+    K+ Y I  G+
Sbjct: 831 NYETRLSEAARPGSNVIQVSATDQDLEYKGKVIYNITDGD 870



 Score =  309 bits (758), Expect = 9e-82
 Identities = 272/916 (29%), Positives = 416/916 (45%), Gaps = 112/916 (12%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V D +D  P F    Y   + E    G+TV+T++A D D+G N  + Y  E+++ ++ 
Sbjct: 141 IEVTDISDMPPRFLQSFYLKEIEENTPIGSTVVTVEARDGDVGINNPILY--EIISGNS- 197

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                             VF ID  +G +    S+D EK   + + VKA++   P S+  
Sbjct: 198 ----------------DGVFTIDSNTGVITVNGSIDAEKTDVFRITVKASEVPDPNSN-- 239

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG-ANSAIRY 189
            +T T+ V ++D NDN P F +  Y   V ED+++    V  +++ TD D       + Y
Sbjct: 240 -TTVTVVVTVVDVNDNRPAFLQSVYIFDVREDVALPGRVVSDQLQVTDGDKNPVFRRVLY 298

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY------------------------RL 225
            ++G ++  +F+ID  SG + + KTLDYE+  ++                        + 
Sbjct: 299 HLVGADSD-KFAIDPTSGTLYINKTLDYEKQINFTFDWERGCGSGGGSGWDWTGRGEEKK 357

Query: 226 VIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD 285
           V+  +   S   S    + + + +VNDN P F  S +  ++ E +  G  I  + A DAD
Sbjct: 358 VVATETDTSEKFSANASVTLTLINVNDNKPMFAKSSYNYTMDEEITPGTHIADITATDAD 417

Query: 286 EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP 345
            G    LTY +      G      +++  +G +  +  LD +T  +YQ  +   DGG   
Sbjct: 418 LGTFGALTYELR-----GGQAAYFSVNADNGTISAAQILDYDTLRQYQFSLVVKDGGGFY 472

Query: 346 RS-ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYE 402
           +  A AT              F    Y  ++AE+ P GT V  +TATD D  E+ RL + 
Sbjct: 473 QEIAIATVTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFN 532

Query: 403 ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ--INIT 460
           I+ G+  G FSI   NG GL+T A+ LD +    Y LTVSA D G  S    VQ  +N+ 
Sbjct: 533 ISAGDDGGHFSI---NGSGLVTTARELDRETIATYTLTVSAYDHGVSSRHKHVQLTVNVL 589

Query: 461 DANNYAP-VFENAPYTASVFEDAPIGTTVLV-VSATDSDVGINAQITYSLSSEISNEAVA 518
           D N+  P + +    T ++ E A  GT +L  ++A D D G N Q+TYS+S         
Sbjct: 590 DENDNTPQITDGLTITTNISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGG------- 642

Query: 519 HHDQQFVINPQTGAITTNKL-LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577
             D +F +N  TG +  +   LDRE    Y L +   D G P  +++T V ++++DVNDN
Sbjct: 643 --DSRFTLNSATGRLQISPTGLDRELKDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDN 700

Query: 578 EPVFK----QQLYTANIMEDALVGT---SVSQVGATDADVGLNGRIHYELDPKDREEGSF 630
            P F     Q L T  I  D   GT   ++  + ATD D   NG++ Y L     E G F
Sbjct: 701 TPAFDPNPAQSLATYVITVDEGPGTINKTLIDINATDPDADANGKVAYSLSGD--EHGFF 758

Query: 631 VIDPASGVIRTNKALDRESV-----ATHD----LKAVAIDGGTP---PQSSTVIVHIKIE 678
            +DP +G +   K LDRES      A  D    L   A D  TP    +S+TV V I + 
Sbjct: 759 RLDPVTGELSVRKELDRESPQMSRNAQGDGRFLLDITATDQATPISDRKSATVRVSITVR 818

Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738
           D ND+ P F+S      +SE +  G+ + ++ A D D      V Y+I  GD++    +E
Sbjct: 819 DTNDNSPQFQSQNYETRLSEAARPGSNVIQVSATDQDLEYKGKVIYNITDGDENRKCEVE 878

Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQ 798
                   +LV      Y   +K    V+   S        V I V DVNDN PV    +
Sbjct: 879 --------KLVR----HYNWHKKN--CVLCKESKCSVERTYVVIYVDDVNDNDPVFNQSK 924

Query: 799 IIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQL 855
              +  ++  P G P  RV A D D     K+ Y++ +GN  +   +N  TG +T++  +
Sbjct: 925 YAADVLENS-PTGTPVLRVHASDRDQGANGKITYKLTNGNKDDAFSINNVTGEITVAGVI 983

Query: 856 NTNVPKLATMEVSVTD 871
           +        + V   D
Sbjct: 984 DREAVHTFVLTVQAED 999



 Score =  304 bits (746), Expect = 2e-80
 Identities = 246/831 (29%), Positives = 402/831 (48%), Gaps = 96/831 (11%)

Query: 140 IIDD-NDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN-TQ 197
           I+DD NDN P F+E+ Y   + E+  V     I KI A DAD G NS ++Y       TQ
Sbjct: 35  IVDDYNDNAPVFTEQPYMAKIAENARV--GTTILKISAIDADSGTNSQVQYKFSNATATQ 92

Query: 198 MQF-SIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256
             F S++S++G+++L   LD+E  RSY LV+ A+D G P   + T ++I + D++D  PR
Sbjct: 93  TPFFSLNSVNGELTLGGPLDFEVARSYMLVVIAEDLGVPKLESRTTVIIEVTDISDMPPR 152

Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316
           F  S + + + EN PIG ++V V+A D D G+N  + Y +     +GN D   TID  +G
Sbjct: 153 FLQSFYLKEIEENTPIGSTVVTVEARDGDVGINNPILYEII----SGNSDGVFTIDSNTG 208

Query: 317 WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376
            +  +G +D E    +++ V A++  DP  + T T              F+   Y  ++ 
Sbjct: 209 VITVNGSIDAEKTDVFRITVKASEVPDPNSNTTVTVVVTVVDVNDNRPAFLQSVYIFDVR 268

Query: 377 EDEP-PGTPVVT-LTATDADED---NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431
           ED   PG  V   L  TD D++    R+ Y + G ++  +F+I   +G   + + + LD+
Sbjct: 269 EDVALPGRVVSDQLQVTDGDKNPVFRRVLYHLVGADS-DKFAIDPTSGT--LYINKTLDY 325

Query: 432 KQERRYV-------------------------LTVSATDSGGR-SDTAMVQINITDANNY 465
           +++  +                          +  + TD+  + S  A V + + + N+ 
Sbjct: 326 EKQINFTFDWERGCGSGGGSGWDWTGRGEEKKVVATETDTSEKFSANASVTLTLINVNDN 385

Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525
            P+F  + Y  ++ E+   GT +  ++ATD+D+G    +TY    E+     A+    F 
Sbjct: 386 KPMFAKSSYNYTMDEEITPGTHIADITATDADLGTFGALTY----ELRGGQAAY----FS 437

Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGG--VPSLSDTTDVEISVVDVNDNEPVFKQ 583
           +N   G I+  ++LD +T+  Y  ++  +DGG     ++  T V +++ DVNDN+P F  
Sbjct: 438 VNADNGTISAAQILDYDTLRQYQFSLVVKDGGGFYQEIAIAT-VTVTLQDVNDNDPEFTG 496

Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK 643
             YT++I E+   GT V QV ATD D G NGR+ + +   D + G F I+  SG++ T +
Sbjct: 497 MPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISAGD-DGGHFSIN-GSGLVTTAR 554

Query: 644 ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP-VFESDCLTFYISENSPI 702
            LDRE++AT+ L   A D G   +   V + + + D ND+ P + +   +T  ISE +  
Sbjct: 555 ELDRETIATYTLTVSAYDHGVSSRHKHVQLTVNVLDENDNTPQITDGLTITTNISEGAGG 614

Query: 703 GTTI-GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761
           GT +   I A DPD G N  + YS+ GGD  + F+L +  G  +   ++   LD E  + 
Sbjct: 615 GTVLLSSIAAVDPDAGSNGQLTYSMSGGD--SRFTLNSATGRLQ---ISPTGLDREL-KD 668

Query: 762 KYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQI-IFNNYKDCFPVGPFGRVP 817
            Y+L+I      SPP  N   V + + DVNDN P            Y      GP G + 
Sbjct: 669 SYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTPAFDPNPAQSLATYVITVDEGP-GTIN 727

Query: 818 AY---------DADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLA----- 863
                      DAD   K+ Y  LSG+      L+  TG +++  +L+   P+++     
Sbjct: 728 KTLIDINATDPDADANGKVAYS-LSGDEHGFFRLDPVTGELSVRKELDRESPQMSRNAQG 786

Query: 864 ----TMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLS 910
                ++++ TD    I      +VR+        SITVR  +  + QF S
Sbjct: 787 DGRFLLDITATDQATPISDRKSATVRV--------SITVRDTNDNSPQFQS 829



 Score =  273 bits (670), Expect = 4e-71
 Identities = 198/629 (31%), Positives = 291/629 (46%), Gaps = 30/629 (4%)

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            +ND +P F  S++  +VSE+   G  I RV A D DEG+NA + Y+      +   +   
Sbjct: 1082 INDESPLFEKSMYYVNVSESASRGIVIGRVTATDRDEGINAIIFYS------SNGAEAKF 1135

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             +   +G +     LDRE +  Y L VTA +     +  T                F   
Sbjct: 1136 YVSRSTGDIIVDSPLDREFKNVYILNVTAANIVAGAQDTTTQVHITVTDVIDDKPYFNSS 1195

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
               V+L+E+   GT V  +TA D D  + + Y I  G+  G F+I +  G  + TVA+ L
Sbjct: 1196 SLTVKLSENASIGTNVTKITALDKDIGDTISYSIANGDPYGLFTIDNVTGE-IRTVAE-L 1253

Query: 430  DFKQERRYVLTVSATDSGGR-SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
            D +   +Y L V A DS    SD   V + + D N+  PVF    YT   +E++P GT++
Sbjct: 1254 DRENVTQYELFVQAKDSVNLVSDLLKVVVQVEDVNDNPPVFSMPGYTIEYWEESPEGTSI 1313

Query: 489  LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT-NKLLDRETMSGY 547
            L V A D+D+G NA + YS+   +++           +N  TG I+  +  LDRE    +
Sbjct: 1314 LQVKAIDADIGDNAAVLYSIVENVTD--------YVTVNAITGVISLGSSQLDREVEEYF 1365

Query: 548  LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
              T+ A D GVPS S T  V I +VD+NDN PVF    Y A + E+   GT V  V A+D
Sbjct: 1366 NFTIRATDSGVPSKSSTASVAIKLVDINDNSPVFNNTDYYAYVRENQPAGTPVLVVTASD 1425

Query: 608  ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
             DVG N ++ Y L         F IDP +G I T + L+RE   ++ L   A+D     +
Sbjct: 1426 KDVGTNAKLSYVLSGVLYTR--FAIDPDTGNITTREPLNREETGSYTLTLRAVDSAIRAR 1483

Query: 668  SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
              T  V I + D ND  P F      F + E+  +G T+G +   D D   NA V Y I 
Sbjct: 1484 EGTTRVIITVTDANDHVPQFTQSGYAFSVREDVKVGHTVGRVATTDEDINDNARVRYYIS 1543

Query: 728  GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILV 784
             G+ S  FS+    G     + T   LD E     Y L+I A     P L ++  V I +
Sbjct: 1544 SGNTSLMFSVNETTGI----ISTTSTLDREQ-NASYTLIITAKDHGIPALESNTSVMITI 1598

Query: 785  TDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILL 842
             DVNDN P+           +  F      +V A D D     +  Y+I +G+  ++  +
Sbjct: 1599 EDVNDNKPLFSKSVYNVTLRESVFLKTQVVQVIATDPDEGANGQFTYKITAGDTDDVFYI 1658

Query: 843  NETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            +  TG +T+  +L+     L  + VS  D
Sbjct: 1659 DANTGLITIKAKLDYEKTSLYNLTVSAQD 1687



 Score =  264 bits (647), Expect = 2e-68
 Identities = 238/821 (28%), Positives = 377/821 (45%), Gaps = 81/821 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT--LKATDQDIGKNAEVEYTI-ELVTA 67
            + V+D ND+ P F    Y   VRE  +    V++  L+ TD D  KN      +  LV A
Sbjct: 246  VTVVDVNDNRPAFLQSVYIFDVREDVALPGRVVSDQLQVTDGD--KNPVFRRVLYHLVGA 303

Query: 68   DT----LNPEDAXXXXXXXXXXVQDV-FRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122
            D+    ++P              + + F  D   G      S            V AT+ 
Sbjct: 304  DSDKFAIDPTSGTLYINKTLDYEKQINFTFDWERGCGSGGGSGWDWTGRGEEKKVVATE- 362

Query: 123  ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
             +  S++ S+ A++ + +I+ NDN P F++ +Y  ++DE+I  T    IA I ATDAD+G
Sbjct: 363  -TDTSEKFSANASVTLTLINVNDNKPMFAKSSYNYTMDEEI--TPGTHIADITATDADLG 419

Query: 183  ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT-T 241
               A+ Y + GG     FS+++ +G +S  + LDY+ +R Y+  +  +DGG   +     
Sbjct: 420  TFGALTYELRGGQAAY-FSVNADNGTISAAQILDYDTLRQYQFSLVVKDGGGFYQEIAIA 478

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
             + + ++DVNDN P F    +   ++EN+P G  + +V A D D G N  L++ ++  D 
Sbjct: 479  TVTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISAGDD 538

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
             G+  +       SG V T+ +LDRET A Y L V+A D G   R               
Sbjct: 539  GGHFSIN-----GSGLVTTARELDRETIATYTLTVSAYDHGVSSRHKHVQLTVNVLDEND 593

Query: 362  XXXXFMPG-QYEVELAEDEPPGTPVVTLTAT---DADEDNRLHYEITGGNTRGRFSITSQ 417
                   G      ++E    GT +++  A    DA  + +L Y ++GG++R  F++ S 
Sbjct: 594  NTPQITDGLTITTNISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGGDSR--FTLNSA 651

Query: 418  NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT--AMVQINITDANNYAPVFENAP-- 473
             GR  I+    LD + +  Y L ++ TD+G   +T    V + I D N+  P F+  P  
Sbjct: 652  TGRLQISPTG-LDRELKDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTPAFDPNPAQ 710

Query: 474  ----YTASVFED-APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528
                Y  +V E    I  T++ ++ATD D   N ++ YSLS +        H   F ++P
Sbjct: 711  SLATYVITVDEGPGTINKTLIDINATDPDADANGKVAYSLSGD-------EHGF-FRLDP 762

Query: 529  QTGAITTNKLLDRET--MSG-------YLLTVTARDGGVPSLSD----TTDVEISVVDVN 575
             TG ++  K LDRE+  MS        +LL +TA D   P +SD    T  V I+V D N
Sbjct: 763  VTGELSVRKELDRESPQMSRNAQGDGRFLLDITATDQATP-ISDRKSATVRVSITVRDTN 821

Query: 576  DNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA 635
            DN P F+ Q Y   + E A  G++V QV ATD D+   G++ Y +   D      V    
Sbjct: 822  DNSPQFQSQNYETRLSEAARPGSNVIQVSATDQDLEYKGKVIYNITDGDENRKCEV---- 877

Query: 636  SGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695
              ++R      +  V   + K             T +V I ++D+ND+ PVF        
Sbjct: 878  EKLVRHYNWHKKNCVLCKESKCSV--------ERTYVV-IYVDDVNDNDPVFNQSKYAAD 928

Query: 696  ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755
            + ENSP GT +  + A D D+G N  + Y +  G+  ++FS+    G    E+     +D
Sbjct: 929  VLENSPTGTPVLRVHASDRDQGANGKITYKLTNGNKDDAFSINNVTG----EITVAGVID 984

Query: 756  YESPRKKYELVIRA--ASPPLWNDVRVEILVT--DVNDNAP 792
             E+    + L ++A     P       E+++T  D NDN P
Sbjct: 985  REAVH-TFVLTVQAEDQGEPSSRKTFAEVVITVKDENDNFP 1024



 Score =  235 bits (575), Expect = 1e-59
 Identities = 188/613 (30%), Positives = 295/613 (48%), Gaps = 66/613 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + + D ND+ P F    Y + + E   +GT V  + ATD+D G+N  + + I        
Sbjct: 482  VTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISA------ 535

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
              +D               F I+G SG + T   LDRE +A YT+ V A D    VS R 
Sbjct: 536  -GDDGGH------------FSING-SGLVTTARELDRETIATYTLTVSAYDHG--VSSR- 578

Query: 131  SSTATIHVNIIDDNDNYPQFSEK-TYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
                 + VN++D+NDN PQ ++  T T ++ E        +++ I A D D G+N  + Y
Sbjct: 579  HKHVQLTVNVLDENDNTPQITDGLTITTNISEGAG-GGTVLLSSIAAVDPDAGSNGQLTY 637

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            ++ GG+++  F+++S +G + +  T LD E   SY L+I   D GSP  +N+T + + I 
Sbjct: 638  SMSGGDSR--FTLNSATGRLQISPTGLDRELKDSYDLIINVTDNGSPPNTNSTTVHVTIL 695

Query: 249  DVNDNAPRFYTSLFQE------SVSENV-PIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
            DVNDN P F  +  Q       +V E    I  +++ + A D D   N ++ Y+++  ++
Sbjct: 696  DVNDNTPAFDPNPAQSLATYVITVDEGPGTINKTLIDINATDPDADANGKVAYSLSGDEH 755

Query: 302  TGNVDL-PIT--IDPRSGWVYTSGQLDRETQA--KYQLLVTATDGGDP---PRSATATXX 353
             G   L P+T  +  R      S Q+ R  Q   ++ L +TATD   P    +SAT    
Sbjct: 756  -GFFRLDPVTGELSVRKELDRESPQMSRNAQGDGRFLLDITATDQATPISDRKSATVRVS 814

Query: 354  XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGR 411
                        F    YE  L+E   PG+ V+ ++ATD D +   ++ Y IT G+   +
Sbjct: 815  ITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQVSATDQDLEYKGKVIYNITDGDENRK 874

Query: 412  FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN 471
              +          + +  ++ ++      V   +S    +   V I + D N+  PVF  
Sbjct: 875  CEVEK--------LVRHYNWHKKN----CVLCKESKCSVERTYVVIYVDDVNDNDPVFNQ 922

Query: 472  APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
            + Y A V E++P GT VL V A+D D G N +ITY L++        + D  F IN  TG
Sbjct: 923  SKYAADVLENSPTGTPVLRVHASDRDQGANGKITYKLTN-------GNKDDAFSINNVTG 975

Query: 532  AITTNKLLDRETMSGYLLTVTARDGGVPSLSDT-TDVEISVVDVNDNEPVFKQQLYTANI 590
             IT   ++DRE +  ++LTV A D G PS   T  +V I+V D NDN P F    Y   I
Sbjct: 976  EITVAGVIDREAVHTFVLTVQAEDQGEPSSRKTFAEVVITVKDENDNFPQFSFTGYEGEI 1035

Query: 591  MEDALVGTSVSQV 603
             E++ VG++++ V
Sbjct: 1036 AENSPVGSTITMV 1048



 Score =  222 bits (542), Expect = 1e-55
 Identities = 188/691 (27%), Positives = 311/691 (45%), Gaps = 61/691 (8%)

Query: 222 SYRLVIRAQD---GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR 278
           +Y   +  +D   GG  +R  +    + + D NDNAP F    +   ++EN  +G +I++
Sbjct: 8   NYEFTVYVEDDFNGGGLARRGSKFFFLIVDDYNDNAPVFTEQPYMAKIAENARVGTTILK 67

Query: 279 VQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA 338
           + A DAD G N+++ Y  ++   T       +++  +G +   G LD E    Y L+V A
Sbjct: 68  ISAIDADSGTNSQVQYKFSNA--TATQTPFFSLNSVNGELTLGGPLDFEVARSYMLVVIA 125

Query: 339 TDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--D 396
            D G P   +  T              F+   Y  E+ E+ P G+ VVT+ A D D   +
Sbjct: 126 EDLGVPKLESRTTVIIEVTDISDMPPRFLQSFYLKEIEENTPIGSTVVTVEARDGDVGIN 185

Query: 397 NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD--SGGRSDTAM 454
           N + YEI  GN+ G F+I S    G+ITV   +D ++   + +TV A++      + T  
Sbjct: 186 NPILYEIISGNSDGVFTIDSNT--GVITVNGSIDAEKTDVFRITVKASEVPDPNSNTTVT 243

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVL--VVSATDSDVG-INAQITYSLSSE 511
           V + + D N+  P F  + Y   V ED  +   V+   +  TD D   +  ++ Y L   
Sbjct: 244 VVVTVVDVNDNRPAFLQSVYIFDVREDVALPGRVVSDQLQVTDGDKNPVFRRVLYHL--- 300

Query: 512 ISNEAVAHHDQQFVINPQTGAITTNKLLDRETM----------------SGYLLTVTARD 555
                V     +F I+P +G +  NK LD E                  SG+  T    +
Sbjct: 301 -----VGADSDKFAIDPTSGTLYINKTLDYEKQINFTFDWERGCGSGGGSGWDWTGRGEE 355

Query: 556 GGVPSL-SDTTD-------VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
             V +  +DT++       V +++++VNDN+P+F +  Y   + E+   GT ++ + ATD
Sbjct: 356 KKVVATETDTSEKFSANASVTLTLINVNDNKPMFAKSSYNYTMDEEITPGTHIADITATD 415

Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
           AD+G  G + YEL  +  +   F ++  +G I   + LD +++  +    V  DGG   Q
Sbjct: 416 ADLGTFGALTYEL--RGGQAAYFSVNADNGTISAAQILDYDTLRQYQFSLVVKDGGGFYQ 473

Query: 668 SSTV-IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
              +  V + ++D+ND+ P F     T  I+EN P GT + ++ A D D G N  + ++I
Sbjct: 474 EIAIATVTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNI 533

Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL---WNDVRVEIL 783
             GDD   FS+    GS    + T  +LD E+    Y L + A    +      V++ + 
Sbjct: 534 SAGDDGGHFSI---NGS--GLVTTARELDRET-IATYTLTVSAYDHGVSSRHKHVQLTVN 587

Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFPVGP--FGRVPAYDADVTDKLQYRILSGNNANLIL 841
           V D NDN P + D   I  N  +    G      + A D D     Q         +   
Sbjct: 588 VLDENDNTPQITDGLTITTNISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGGDSRFT 647

Query: 842 LNETTGSMTLSPQ-LNTNVPKLATMEVSVTD 871
           LN  TG + +SP  L+  +     + ++VTD
Sbjct: 648 LNSATGRLQISPTGLDRELKDSYDLIINVTD 678



 Score =  175 bits (425), Expect = 2e-41
 Identities = 146/426 (34%), Positives = 206/426 (48%), Gaps = 26/426 (6%)

Query: 452  TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE 511
            TA  +  IT  N+ +P+FE + Y  +V E A  G  +  V+ATD D GINA I YS    
Sbjct: 1072 TAREKRPITLINDESPLFEKSMYYVNVSESASRGIVIGRVTATDRDEGINAIIFYS---- 1127

Query: 512  ISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571
             SN A A    +F ++  TG I  +  LDRE  + Y+L VTA +    +   TT V I+V
Sbjct: 1128 -SNGAEA----KFYVSRSTGDIIVDSPLDREFKNVYILNVTAANIVAGAQDTTTQVHITV 1182

Query: 572  VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631
             DV D++P F     T  + E+A +GT+V+++ A D D+G    I Y +   D   G F 
Sbjct: 1183 TDVIDDKPYFNSSSLTVKLSENASIGTNVTKITALDKDIG--DTISYSIANGD-PYGLFT 1239

Query: 632  IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691
            ID  +G IRT   LDRE+V  ++L   A D      S  + V +++ED+ND+PPVF    
Sbjct: 1240 IDNVTGEIRTVAELDRENVTQYELFVQAKD-SVNLVSDLLKVVVQVEDVNDNPPVFSMPG 1298

Query: 692  LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751
             T    E SP GT+I +++A D D G NA V YSI      N     T         +  
Sbjct: 1299 YTIEYWEESPEGTSILQVKAIDADIGDNAAVLYSIV----ENVTDYVTVNAITGVISLGS 1354

Query: 752  VDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCF 808
              LD E   + +   IRA     P   +   V I + D+NDN+PV  +    +   ++  
Sbjct: 1355 SQLDRE-VEEYFNFTIRATDSGVPSKSSTASVAIKLVDINDNSPVFNNTD-YYAYVRENQ 1412

Query: 809  PVG-PFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATM 865
            P G P   V A D DV    KL Y +LSG       ++  TG++T    LN       T+
Sbjct: 1413 PAGTPVLVVTASDKDVGTNAKLSY-VLSGVLYTRFAIDPDTGNITTREPLNREETGSYTL 1471

Query: 866  EVSVTD 871
             +   D
Sbjct: 1472 TLRAVD 1477



 Score =  136 bits (329), Expect = 8e-30
 Identities = 101/320 (31%), Positives = 160/320 (50%), Gaps = 17/320 (5%)

Query: 574  VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633
            +ND  P+F++ +Y  N+ E A  G  + +V ATD D G+N  I Y     +  E  F + 
Sbjct: 1082 INDESPLFEKSMYYVNVSESASRGIVIGRVTATDRDEGINAIIFYS---SNGAEAKFYVS 1138

Query: 634  PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693
             ++G I  +  LDRE    + L   A +     Q +T  VHI + D+ D  P F S  LT
Sbjct: 1139 RSTGDIIVDSPLDREFKNVYILNVTAANIVAGAQDTTTQVHITVTDVIDDKPYFNSSSLT 1198

Query: 694  FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753
              +SEN+ IGT + +I A D D G    + YSI  GD    F+++   G    E+ T+ +
Sbjct: 1199 VKLSENASIGTNVTKITALDKDIGD--TISYSIANGDPYGLFTIDNVTG----EIRTVAE 1252

Query: 754  LDYESPRKKYELVIRAA-SPPLWND-VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811
            LD E+   +YEL ++A  S  L +D ++V + V DVNDN PV          +++     
Sbjct: 1253 LDRENV-TQYELFVQAKDSVNLVSDLLKVVVQVEDVNDNPPVFSMPGYTIEYWEESPEGT 1311

Query: 812  PFGRVPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTL-SPQLNTNVPKLATMEVS 868
               +V A DAD+ D   + Y I+  N  + + +N  TG ++L S QL+  V +     + 
Sbjct: 1312 SILQVKAIDADIGDNAAVLYSIVE-NVTDYVTVNAITGVISLGSSQLDREVEEYFNFTIR 1370

Query: 869  VTD-GVNEIKAMMQLSVRLI 887
             TD GV    +   ++++L+
Sbjct: 1371 ATDSGVPSKSSTASVAIKLV 1390



 Score =  120 bits (289), Expect = 6e-25
 Identities = 100/344 (29%), Positives = 163/344 (47%), Gaps = 40/344 (11%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDI-GKNAEVEYTIELVTAD 68
            +I+V D +D++PVF   +Y A + E  + G  V+T+ ATD D    +  V Y IE    D
Sbjct: 1700 EIHVSDVDDNAPVFHKPRYSAELYENVTRGHHVITVNATDIDAEASHKRVYYRIESGNTD 1759

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS----LDREKVARYTVLVKATDQAS 124
            ++                   F I  +SG +    +    L+RE  ARY + V A  + +
Sbjct: 1760 SM-------------------FLIGEQSGVITLNCTPSGCLNRETHARYELQVAAISRVN 1800

Query: 125  PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184
             ++++ S    + + ++D NDN P+F  ++Y  SV ED     +  I  +KA D D G +
Sbjct: 1801 -LTEQKSLVPAV-ITVLDVNDNAPRFDSESYVRSVLEDTGPITDATILTVKAQDGDEGES 1858

Query: 185  SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
              I + I+ GN    F +D+ +G ++  + LD E    Y LV+ A+D G P+ S++  + 
Sbjct: 1859 GEIIFTIVSGNENGVFQMDNKTGVLTRTRPLDREDTSFYSLVVMAEDKGEPALSSSVTVN 1918

Query: 245  INIRDVNDNAPRFYTS---LFQE-----SVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
            I + D+NDN P   T    L  E     SV EN+  G  +  V A D D      + Y +
Sbjct: 1919 ITVLDMNDNLPILQTPMDVLIPERRTTFSVKENLDAGVPVGVVAAQDLD--TKNLIYYYI 1976

Query: 297  TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD 340
            T+ +          ++  SG + T   LDRE  + + L V A++
Sbjct: 1977 TNTE----EQKYFILNETSGELRTRITLDREDSSVHYLYVKASN 2016



 Score =   99 bits (238), Expect = 9e-19
 Identities = 59/145 (40%), Positives = 85/145 (58%), Gaps = 2/145 (1%)

Query: 563  DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP 622
            + T V I V DVNDN+PVF Q  Y A+++E++  GT V +V A+D D G NG+I Y+L  
Sbjct: 902  ERTYVVIYVDDVNDNDPVFNQSKYAADVLENSPTGTPVLRVHASDRDQGANGKITYKLTN 961

Query: 623  KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI-VHIKIEDIN 681
             ++++ +F I+  +G I     +DRE+V T  L   A D G P    T   V I ++D N
Sbjct: 962  GNKDD-AFSINNVTGEITVAGVIDREAVHTFVLTVQAEDQGEPSSRKTFAEVVITVKDEN 1020

Query: 682  DSPPVFESDCLTFYISENSPIGTTI 706
            D+ P F        I+ENSP+G+TI
Sbjct: 1021 DNFPQFSFTGYEGEIAENSPVGSTI 1045



 Score = 50.0 bits (114), Expect = 0.001
 Identities = 23/56 (41%), Positives = 32/56 (57%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
           +   I V D ND+SP F+ Q YE  + E A  G+ V+ + ATDQD+    +V Y I
Sbjct: 811 VRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQVSATDQDLEYKGKVIYNI 866


>UniRef50_A7S751 Cluster: Predicted protein; n=1; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 2676

 Score =  385 bits (947), Expect = e-104
 Identities = 284/886 (32%), Positives = 427/886 (48%), Gaps = 70/886 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +N+ D ND+ P F    Y AS+ E + SG+ V+ L A D DIG+N+ + Y+I       L
Sbjct: 486  VNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSI-------L 538

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             P                 F +D R G +    +LD E  + YT  V ATD         
Sbjct: 539  TPNTP--------------FFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGGR----- 579

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S  AT+HV++ D NDN P F   +Y+V   E+  +  +  I ++KA D D    +  R+ 
Sbjct: 580  SCNATVHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQS--ICQLKAIDRDSPKFAITRFI 637

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I  GN    FS+D  SG ++L K LD E   +Y L ++A DGG     N   + I + DV
Sbjct: 638  IEQGNADEVFSVDG-SGLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDV 696

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            ND  P F  + +  ++ E+      I  V A   D+G NAE+ Y+++     GN D  + 
Sbjct: 697  NDEPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSISK----GNTDNIVL 752

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            I+  +G +Y   ++D E      L V A D G PP    A               F    
Sbjct: 753  INS-TGTLYLQSEVDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSSS 811

Query: 371  YEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
              V L ED P G    T++  DAD     R+ + +   N    F++ S  G   +++ + 
Sbjct: 812  ILVRLPEDTPIGHTFYTVSVFDADSGVLGRVSFSLLS-NPGTLFNLDSNTGA--LSLTKL 868

Query: 429  LDF-KQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
            +D+    R Y L V A D G   RS TAM+++ + D N+Y+PVF N  YTA V E  P  
Sbjct: 869  IDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLETTPPD 928

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
            + ++ V ATD D G N +I+Y+  S++          +F +    G I     LDRE + 
Sbjct: 929  SNIIEVVATDVDSGENGRISYAFDSKVDTS-------KFGLR-NGGKIFIKSKLDREDIE 980

Query: 546  GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
             Y L V A D G P  S + DV++ V DVNDN P F+Q  Y   + E+  V T +  V A
Sbjct: 981  EYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHFQQASYAFFVKENEPVATYLGAVSA 1040

Query: 606  TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
            +D+D G NG + Y  D    +   F++D  +G I T++ LDRE+ A++    VA DGG+ 
Sbjct: 1041 SDSDEGSNGHVTYRFDT---QVAQFIVDKQTGKITTSQVLDREAKASYVFSIVATDGGSS 1097

Query: 666  PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE-GPNAVVHY 724
            P+     V + + D+ND  P F  +  +  ++E+ P+G+++  + A D D+ GPN+ + Y
Sbjct: 1098 PRVDKTQVTVIVRDVNDCSPKFSKNKYSVTVNEDLPVGSSLLTLIATDDDQQGPNSDITY 1157

Query: 725  SIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVI---RAASPPLWNDVRV 780
             I  G    +FSL    G     ++T+V  LD E   +    V+   +  +  L     +
Sbjct: 1158 MIVAGP--KAFSLNQVTG-----VLTLVSPLDREVTHRHILHVVASDKGGNQSLETITYI 1210

Query: 781  EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTD--KLQYRILSGNNA 837
            EI V DVNDN PV  + +  F    +  P+G     V A D+D  D  K++Y+I++GN  
Sbjct: 1211 EINVLDVNDNYPVFIN-ETTFKTVPEKLPIGSVVAAVLAVDSDQGDNGKVRYKIVNGNTD 1269

Query: 838  NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQL 882
                +NETTG ++    L+  V     + VS TD G  + K   QL
Sbjct: 1270 GTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQL 1315



 Score =  363 bits (892), Expect = 5e-98
 Identities = 281/874 (32%), Positives = 419/874 (47%), Gaps = 64/874 (7%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +INV D ND +P F+   YE  V E A+  T V  + A DQD G N+E+ YTI    A+T
Sbjct: 376  RINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTI----ANT 431

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                                F ID  SG + T   LDRE++ +  + V   D+ SP    
Sbjct: 432  TESRSYLHW-----------FAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPP--- 477

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            LS   ++ VN+ D NDN P F++ +Y  S+ E+ S + +PV+ ++ A D D+G NS I Y
Sbjct: 478  LSDNCSVIVNLTDSNDNDPYFNQSSYNASLFEN-SPSGSPVV-QLLAQDPDIGENSLILY 535

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            +I+  NT   F +D   G V+  +TLD+E   SY   + A DGG  S + T    +++ D
Sbjct: 536  SILTPNTP--FFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGGRSCNATVH--VSLTD 591

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            +NDN P F  S +     EN  IG SI +++A D D    A   + +      GN D   
Sbjct: 592  LNDNQPVFDPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQ----GNADEVF 647

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            ++D  SG +  +  LDRETQ  Y L V A DGG       A               F   
Sbjct: 648  SVDG-SGLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKA 706

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNGRGLITVAQ 427
            +Y   + E     + +  + A   D+       Y I+ GNT    +I   N  G + +  
Sbjct: 707  EYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSISKGNTD---NIVLINSTGTLYLQS 763

Query: 428  PLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
             +D ++     LTV A D G       A V I + D N+ +P F ++     + ED PIG
Sbjct: 764  EVDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSSSILVRLPEDTPIG 823

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR-ETM 544
             T   VS  D+D G+  ++++SL   +SN         F ++  TGA++  KL+D   + 
Sbjct: 824  HTFYTVSVFDADSGVLGRVSFSL---LSNPGTL-----FNLDSNTGALSLTKLIDYGNSA 875

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
              Y L V A+DGG P  S T  +E+ VVDVND  PVF    YTA+++E     +++ +V 
Sbjct: 876  RSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLETTPPDSNIIEVV 935

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            ATD D G NGRI Y  D K  +   F +     +   +K LDRE +  ++LK +AID GT
Sbjct: 936  ATDVDSGENGRISYAFDSKV-DTSKFGLRNGGKIFIKSK-LDREDIEEYNLKVIAIDHGT 993

Query: 665  PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
            P +SS+  V + ++D+ND+ P F+     F++ EN P+ T +G + A D DEG N   H 
Sbjct: 994  PRRSSSADVKVIVDDVNDNNPHFQQASYAFFVKENEPVATYLGAVSASDSDEGSNG--HV 1051

Query: 725  SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVE 781
            + +       F ++ + G    ++ T   LD E+ +  Y   I A    S P  +  +V 
Sbjct: 1052 TYRFDTQVAQFIVDKQTG----KITTSQVLDREA-KASYVFSIVATDGGSSPRVDKTQVT 1106

Query: 782  ILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD---VTDKLQYRILSGNNA 837
            ++V DVND +P     +      +D  PVG     + A D D       + Y I++G  A
Sbjct: 1107 VIVRDVNDCSPKFSKNKYSVTVNED-LPVGSSLLTLIATDDDQQGPNSDITYMIVAGPKA 1165

Query: 838  NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
                LN+ TG +TL   L+  V     + V  +D
Sbjct: 1166 --FSLNQVTGVLTLVSPLDREVTHRHILHVVASD 1197



 Score =  359 bits (883), Expect = 6e-97
 Identities = 252/821 (30%), Positives = 395/821 (48%), Gaps = 49/821 (5%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V D ND+ P F    Y  ++ E    GT++L + A+D+DIG NAE++Y+IE  +    
Sbjct: 160 ITVEDTNDNKPEFSNVSYSGTIPENIDVGTSILQVSASDKDIGTNAEIQYSIETHS---- 215

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           +P              Q +F I   +G ++    LD E    Y ++VKA D+ S  S +L
Sbjct: 216 DP--------------QAIFGIHPTTGVIVNNVRLDYEAKRSYLIVVKAEDKGS--SHQL 259

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI--SVTDNPVIAKIKATDADVGANSAIR 188
           SS+A + + ++D NDN P     +YT+     +  + T    +A++  +DAD G N  + 
Sbjct: 260 SSSAIVRIEVLDVNDNNPVI-HVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVN 318

Query: 189 YAIIGGNTQMQFSIDSLSGD--VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
             + GG+       D L+ +  +++ ++LD E    + L     D G P R+      IN
Sbjct: 319 VTLEGGDGYFSMKFDVLNDESIIAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRIN 378

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
           + DVND AP+F    ++  V EN  +   +  V A D D G N+EL YT+ +   + +  
Sbjct: 379 VGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYL 438

Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
               IDP SG + T+  LDRE   +  L V   D G PP S   +              F
Sbjct: 439 HWFAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYF 498

Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLIT 424
               Y   L E+ P G+PVV L A D D  E++ + Y I   NT   F +  +  +GL+T
Sbjct: 499 NQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSILTPNT--PFFLDPR--KGLVT 554

Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
            ++ LD + +  Y   V+ATD GGRS  A V +++TD N+  PVF+ + Y+   FE+  I
Sbjct: 555 NSRTLDHEVQSSYTFQVAATDGGGRSCNATVHVSLTDLNDNQPVFDPSSYSVEYFENTRI 614

Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
           G ++  + A D D        ++++  I  +  A  D+ F ++  +G IT  KLLDRET 
Sbjct: 615 GQSICQLKAIDRD-----SPKFAITRFIIEQGNA--DEVFSVD-GSGLITLAKLLDRETQ 666

Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
             YLLTV A DGG     +   V I+V+DVND  P+F +  Y   I E +   + +  V 
Sbjct: 667 DNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQEHSQALSVIGHVH 726

Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
           A   D G N  + Y +   + +  + V+  ++G +     +D E + +  L   A D GT
Sbjct: 727 AISRDKGTNAEVVYSISKGNTD--NIVLINSTGTLYLQSEVDHEKIPSLYLTVQAKDKGT 784

Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
           PP      V I + DIND+ P F S  +   + E++PIG T   +   D D G    V +
Sbjct: 785 PPLFGYANVTIAVIDINDNSPQFNSSSILVRLPEDTPIGHTFYTVSVFDADSGVLGRVSF 844

Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVE 781
           S+   +    F+L++  G+    L  ++  DY +  + Y L ++A    SPP  +   +E
Sbjct: 845 SLL-SNPGTLFNLDSNTGA--LSLTKLI--DYGNSARSYTLPVQAQDGGSPPRSSTAMLE 899

Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD 822
           + V DVND +PV  ++    +  +   P      V A D D
Sbjct: 900 LKVVDVNDYSPVFGNWSYTAHVLETTPPDSNIIEVVATDVD 940



 Score =  356 bits (876), Expect = 4e-96
 Identities = 272/876 (31%), Positives = 412/876 (47%), Gaps = 60/876 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND+ P F+       + E     T V T+KA D D G N+ + YTI     D+ 
Sbjct: 1318 IYVEDANDNRPTFDKNPIITWIYENVPINTNVTTIKAHDDDSGLNSRIWYTI-----DSQ 1372

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +P                 F+I+  +G + T   +DRE+++ Y++ V+ATDQA    DRL
Sbjct: 1373 SPRAH--------------FKINSETGLIQTTHPIDREEISEYSLKVRATDQAFTEQDRL 1418

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             +TAT+ + I D NDN P+F  +  T  ++++     N  +  I A D D G    + Y 
Sbjct: 1419 YNTATLKIIIQDLNDNAPKFVSRNLTYVMEDE---PFNFQVTSITALDPDTGQGGNVEYR 1475

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I+  +T  +FS+D  +G + L+ +LDYE V  Y L I A D GSP  ++     + + DV
Sbjct: 1476 IVSPDTG-KFSLDLKTGVLKLIGSLDYEDVPQYTLHISATDLGSPPLTSYQLFNVVVVDV 1534

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN P F   LF  +VSEN P G S+V+V AYD D G NAELTY++     +G      +
Sbjct: 1535 NDNPPEFTRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELTYSIP----SGVEMDKFS 1590

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            ID  SG + T+  LDRE +  Y L V AT    P R ++ +              F+   
Sbjct: 1591 IDKHSGLIVTNSILDREKKDTYFLTVHATGVSYPFRVSSTSVRINVMDRNDNPPKFISPV 1650

Query: 371  YEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
              +++ E+  P   + TLT  D D  N  ++ Y I  GNT G F+I    G   ++    
Sbjct: 1651 VTLKVPENS-PARLIYTLTVQDLDYGNNTKVLYSIMSGNTDGAFTIGRSTGE--LSTTTK 1707

Query: 429  LDFKQERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYAPVFENAPYTASVFEDAPIGT 486
            LD + +  Y L+V A D      TA   I   I D N+  PVF+ + Y++++ E  P GT
Sbjct: 1708 LDRETKASYQLSVQAKDITPPYYTAFANITIFIEDQNDNPPVFQQSLYSSTISELTPPGT 1767

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
            ++L ++A+D D G N  I Y+LS++            + I+ +TG + +    +      
Sbjct: 1768 SILNLTASDKDSGSNGNIVYTLSNDTYG--------VYSIDSRTGIVYSAARFETSIKQE 1819

Query: 547  YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
            Y     A+D G         V I + D N++ P F +  Y  +I  +      V+ V AT
Sbjct: 1820 YNFFCIAKDQGQDPKMAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTAT 1879

Query: 607  DADV--GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            DAD     NG++ Y LD        FV++  +G +RT+          H L  +A D G+
Sbjct: 1880 DADTDKSTNGKVTYRLDDSKNSTSLFVVESNTGSVRTSAGFSNPPQGRHALYIIAEDHGS 1939

Query: 665  PPQSSTVIVHIKIEDINDSPPVFESDC-LTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
            PP     IV I I +I D PP F +       I ENS +G+ I  +RA       +A V 
Sbjct: 1940 PPLRGYGIVQIVIGNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRAR---ASSDAQVT 1996

Query: 724  YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR---- 779
            YSI  G+   +F ++   G     + +   LDYES  K + L +  A+P  W  +     
Sbjct: 1997 YSIISGNKGRAFYVDPFTG--VISVASADALDYES-TKNFRLHL-VATPQGWVSLNGYMI 2052

Query: 780  VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP--FGRVPAYDAD--VTDKLQYRILSGN 835
            ++I V D NDN+P      ++    +D     P    +V A D D     K+ Y I +GN
Sbjct: 2053 LDINVIDRNDNSPAFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGN 2112

Query: 836  NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
             A +  ++ TTG +T +  L+        + +  TD
Sbjct: 2113 EAGVFTIDSTTGEITTAKLLDRETTASFDLVIRGTD 2148



 Score =  351 bits (863), Expect = 2e-94
 Identities = 265/876 (30%), Positives = 396/876 (45%), Gaps = 60/876 (6%)

Query: 10   QINVLDCNDHSPVFEMQQY---EASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            +I VLD ND++PV  +         V E A+ GT V  +  +D D GKN EV  T+E   
Sbjct: 266  RIEVLDVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTLE--- 322

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
                                   F +      +    SLDRE    + +     D+  P 
Sbjct: 323  --------------GGDGYFSMKFDVLNDESIIAVGQSLDRETHDHFFLKAVCIDKGDPP 368

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
                ++  +  +N+ D ND  P+F   TY   V E+ +V  N ++A + A D D G+NS 
Sbjct: 369  R---TTEKSFRINVGDVNDCAPKFDRHTYETRVWENATV--NTLVAIVNAVDQDFGSNSE 423

Query: 187  IRYAIIGGNTQMQ----FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
            + Y I            F+ID  SG ++    LD EQ+    L +   D GSP  S+   
Sbjct: 424  LVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCS 483

Query: 243  LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
            +++N+ D NDN P F  S +  S+ EN P G  +V++ A D D G N+ + Y++     T
Sbjct: 484  VIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSI----LT 539

Query: 303  GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
             N   P  +DPR G V  S  LD E Q+ Y   V ATDGG   RS  AT           
Sbjct: 540  PNT--PFFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGG--RSCNATVHVSLTDLNDN 595

Query: 363  XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGR 420
               F P  Y VE  E+   G  +  L A D D        + I  GN    FS+   +G 
Sbjct: 596  QPVFDPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQGNADEVFSV---DGS 652

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASV 478
            GLIT+A+ LD + +  Y+LTV A D GG+   + A+V I + D N+  P+F  A Y  ++
Sbjct: 653  GLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTI 712

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             E +   + +  V A   D G NA++ YS+S         + D   +IN  TG +     
Sbjct: 713  QEHSQALSVIGHVHAISRDKGTNAEVVYSISK-------GNTDNIVLIN-STGTLYLQSE 764

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            +D E +    LTV A+D G P L    +V I+V+D+NDN P F        + ED  +G 
Sbjct: 765  VDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSSSILVRLPEDTPIGH 824

Query: 599  SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD-RESVATHDLKA 657
            +   V   DAD G+ GR+ + L         F +D  +G +   K +D   S  ++ L  
Sbjct: 825  TFYTVSVFDADSGVLGRVSFSL--LSNPGTLFNLDSNTGALSLTKLIDYGNSARSYTLPV 882

Query: 658  VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
             A DGG+PP+SST ++ +K+ D+ND  PVF +   T ++ E +P  + I E+ A D D G
Sbjct: 883  QAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLETTPPDSNIIEVVATDVDSG 942

Query: 718  PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND 777
             N  + Y+     D++ F L  R G  K  + + +D +         + I   +P   + 
Sbjct: 943  ENGRISYAFDSKVDTSKFGL--RNGG-KIFIKSKLDREDIEEYNLKVIAIDHGTPRRSSS 999

Query: 778  VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDKLQYRILSGNN 836
              V+++V DVNDN P  +     F   K+  PV  + G V A D+D              
Sbjct: 1000 ADVKVIVDDVNDNNPHFQQASYAF-FVKENEPVATYLGAVSASDSDEGSNGHVTYRFDTQ 1058

Query: 837  ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
                ++++ TG +T S  L+          +  TDG
Sbjct: 1059 VAQFIVDKQTGKITTSQVLDREAKASYVFSIVATDG 1094



 Score =  348 bits (856), Expect = 1e-93
 Identities = 271/895 (30%), Positives = 423/895 (47%), Gaps = 59/895 (6%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + V D ND+SP F ++   A +    +       L A D D G N+   YTI  V+ +  
Sbjct: 46  VYVQDLNDNSPSF-VRGTSAKLVVFENDKDFRQKLIAVDSDFGSNSTQSYTI--VSGNVG 102

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           N                D+  ++  S        +DRE++  Y + + A+D  +P +   
Sbjct: 103 NVFKLISKRDTDGDLYADLV-VNASS------IGVDRERLDSYVLNISASDGGNPAN--- 152

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
                + + + D NDN P+FS  +Y+ ++ E+I V  +  I ++ A+D D+G N+ I+Y+
Sbjct: 153 HGFLRLSITVEDTNDNKPEFSNVSYSGTIPENIDVGTS--ILQVSASDKDIGTNAEIQYS 210

Query: 191 I-IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIR 248
           I    + Q  F I   +G +     LDYE  RSY +V++A+D GS  + +++ ++ I + 
Sbjct: 211 IETHSDPQAIFGIHPTTGVIVNNVRLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVL 270

Query: 249 DVNDNAPRF---YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
           DVNDN P     YT      V+EN  IG  + RV   DAD G N E+  T+   D  G  
Sbjct: 271 DVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTLEGGD--GYF 328

Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
            +   +      +     LDRET   + L     D GDPPR+   +              
Sbjct: 329 SMKFDVLNDESIIAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPK 388

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS----ITSQNGRG 421
           F    YE  + E+    T V  + A D D  +      T  NT    S           G
Sbjct: 389 FDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSG 448

Query: 422 LITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVF 479
           +IT A  LD +Q  + VLTV   D G    SD   V +N+TD+N+  P F  + Y AS+F
Sbjct: 449 MITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLF 508

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           E++P G+ V+ + A D D+G N+ I YS+ +          +  F ++P+ G +T ++ L
Sbjct: 509 ENSPSGSPVVQLLAQDPDIGENSLILYSILTP---------NTPFFLDPRKGLVTNSRTL 559

Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
           D E  S Y   V A DGG  S + T  V +S+ D+NDN+PVF    Y+    E+  +G S
Sbjct: 560 DHEVQSSYTFQVAATDGGGRSCNAT--VHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQS 617

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
           + Q+ A D D        + ++  + +E  F +D  SG+I   K LDRE+   + L   A
Sbjct: 618 ICQLKAIDRDSPKFAITRFIIEQGNADE-VFSVD-GSGLITLAKLLDRETQDNYLLTVKA 675

Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
           +DGG     +  IV+I + D+ND PP+F      F I E+S   + IG + A   D+G N
Sbjct: 676 VDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTN 735

Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776
           A V YSI  G+  N   +     +    L    ++D+E     Y L ++A    +PPL+ 
Sbjct: 736 AEVVYSISKGNTDNIVLI-----NSTGTLYLQSEVDHEKIPSLY-LTVQAKDKGTPPLFG 789

Query: 777 DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILS 833
              V I V D+NDN+P      I+    +D  P+G  F  V  +DAD  V  ++ + +LS
Sbjct: 790 YANVTIAVIDINDNSPQFNSSSILVRLPEDT-PIGHTFYTVSVFDADSGVLGRVSFSLLS 848

Query: 834 GNNANLILLNETTGSMTLSPQLN-TNVPKLATMEVSVTDGVNEIK---AMMQLSV 884
            N   L  L+  TG+++L+  ++  N  +  T+ V   DG +  +   AM++L V
Sbjct: 849 -NPGTLFNLDSNTGALSLTKLIDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKV 902



 Score =  339 bits (833), Expect = 7e-91
 Identities = 257/856 (30%), Positives = 410/856 (47%), Gaps = 63/856 (7%)

Query: 13   VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDI-GKNAEVEYTIELVTADTLN 71
            V D ND SP F   +Y  +V E    G+++LTL ATD D  G N+++ Y I         
Sbjct: 1109 VRDVNDCSPKFSKNKYSVTVNEDLPVGSSLLTLIATDDDQQGPNSDITYMI------VAG 1162

Query: 72   PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131
            P+                F ++  +G L   + LDRE   R+ + V A+D+    S  L 
Sbjct: 1163 PK---------------AFSLNQVTGVLTLVSPLDREVTHRHILHVVASDKGGNQS--LE 1205

Query: 132  STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191
            +   I +N++D NDNYP F  +T   +V E + +    V+A + A D+D G N  +RY I
Sbjct: 1206 TITYIEINVLDVNDNYPVFINETTFKTVPEKLPI--GSVVAAVLAVDSDQGDNGKVRYKI 1263

Query: 192  IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIRDV 250
            + GNT   F I+  +G +S ++ LD+E    Y L + A D G   +  + QL+ I + D 
Sbjct: 1264 VNGNTDGTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQLVTIYVEDA 1323

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN P F  +     + ENVPI  ++  ++A+D D G+N+ + YT+  +    +      
Sbjct: 1324 NDNRPTFDKNPIITWIYENVPINTNVTTIKAHDDDSGLNSRIWYTIDSQSPRAH----FK 1379

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA---TATXXXXXXXXXXXXXXFM 367
            I+  +G + T+  +DRE  ++Y L V ATD     +     TAT              F+
Sbjct: 1380 INSETGLIQTTHPIDREEISEYSLKVRATDQAFTEQDRLYNTATLKIIIQDLNDNAPKFV 1439

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITV 425
              +    + EDEP    V ++TA D D  +   + Y I   +T G+FS+  +   G++ +
Sbjct: 1440 -SRNLTYVMEDEPFNFQVTSITALDPDTGQGGNVEYRIVSPDT-GKFSLDLKT--GVLKL 1495

Query: 426  AQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTASVFEDAP 483
               LD++   +Y L +SATD G    T+  +  + + D N+  P F    +  +V E+ P
Sbjct: 1496 IGSLDYEDVPQYTLHISATDLGSPPLTSYQLFNVVVVDVNDNPPEFTRDLFIGTVSENKP 1555

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
             GT+V+ V+A D D G NA++TYS+ S +  +       +F I+  +G I TN +LDRE 
Sbjct: 1556 TGTSVVKVTAYDRDSGSNAELTYSIPSGVEMD-------KFSIDKHSGLIVTNSILDREK 1608

Query: 544  MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
               Y LTV A     P    +T V I+V+D NDN P F   + T  + E++     +  +
Sbjct: 1609 KDTYFLTVHATGVSYPFRVSSTSVRINVMDRNDNPPKFISPVVTLKVPENS-PARLIYTL 1667

Query: 604  GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
               D D G N ++ Y +      +G+F I  ++G + T   LDRE+ A++ L   A D  
Sbjct: 1668 TVQDLDYGNNTKVLYSI-MSGNTDGAFTIGRSTGELSTTTKLDRETKASYQLSVQAKDIT 1726

Query: 664  TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
             P  ++   + I IED ND+PPVF+    +  ISE +P GT+I  + A D D G N  + 
Sbjct: 1727 PPYYTAFANITIFIEDQNDNPPVFQQSLYSSTISELTPPGTSILNLTASDKDSGSNGNIV 1786

Query: 724  YSIKGGDDSNSFSLETRQG--SDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781
            Y++   D    +S+++R G     A   T +  +Y      + +       P    V V 
Sbjct: 1787 YTL-SNDTYGVYSIDSRTGIVYSAARFETSIKQEYNF----FCIAKDQGQDPKMAIVPVR 1841

Query: 782  ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD----VTDKLQYRI-LSGNN 836
            I + D N++AP         + + +         V A DAD       K+ YR+  S N+
Sbjct: 1842 IKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYRLDDSKNS 1901

Query: 837  ANLILLNETTGSMTLS 852
             +L ++   TGS+  S
Sbjct: 1902 TSLFVVESNTGSVRTS 1917



 Score =  327 bits (804), Expect = 2e-87
 Identities = 234/796 (29%), Positives = 380/796 (47%), Gaps = 54/796 (6%)

Query: 92  IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151
           ++  +G + T+  LDREKV+ Y + +   + ++P       + T+ V + D NDN P F 
Sbjct: 7   LEYNAGVITTKTVLDREKVSAYNLTI--VEFSTP-----PKSYTVLVYVQDLNDNSPSFV 59

Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS---LSGD 208
             T    V   +   D     K+ A D+D G+NS   Y I+ GN    F + S     GD
Sbjct: 60  RGTSAKLV---VFENDKDFRQKLIAVDSDFGSNSTQSYTIVSGNVGNVFKLISKRDTDGD 116

Query: 209 V--SLVKT-----LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261
           +   LV       +D E++ SY L I A DGG+P+     +L I + D NDN P F    
Sbjct: 117 LYADLVVNASSIGVDRERLDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVS 176

Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321
           +  ++ EN+ +G SI++V A D D G NAE+ Y++   +   +      I P +G +  +
Sbjct: 177 YSGTIPENIDVGTSILQVSASDKDIGTNAEIQYSI---ETHSDPQAIFGIHPTTGVIVNN 233

Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV----ELAE 377
            +LD E +  Y ++V A D G   + +++                +   Y +    ++ E
Sbjct: 234 VRLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVSYTLGGSYQVTE 293

Query: 378 DEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ--NGRGLITVAQPLDFKQER 435
           +   GT V  ++ +DAD        +T     G FS+     N   +I V Q LD +   
Sbjct: 294 NATIGTQVARVSVSDADSGKNGEVNVTLEGGDGYFSMKFDVLNDESIIAVGQSLDRETHD 353

Query: 436 RYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
            + L     D G   R+     +IN+ D N+ AP F+   Y   V+E+A + T V +V+A
Sbjct: 354 HFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNA 413

Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553
            D D G N+++ Y++++   + +  H    F I+P +G ITT   LDRE +   +LTV  
Sbjct: 414 VDQDFGSNSELVYTIANTTESRSYLHW---FAIDPSSGMITTATDLDREQIPQVVLTVLV 470

Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613
            D G P LSD   V +++ D NDN+P F Q  Y A++ E++  G+ V Q+ A D D+G N
Sbjct: 471 HDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGEN 530

Query: 614 GRIHYE-LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672
             I Y  L P       F +DP  G++  ++ LD E  +++  +  A DGG   +S    
Sbjct: 531 SLILYSILTPNT----PFFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGG--GRSCNAT 584

Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732
           VH+ + D+ND+ PVF+    +    EN+ IG +I +++A D D    A+  + I+ G+  
Sbjct: 585 VHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQGNAD 644

Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVND 789
             FS+      D + L+T+  L     +  Y L ++A         N   V I V DVND
Sbjct: 645 EVFSV------DGSGLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVND 698

Query: 790 NAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTG 847
             P+    +  F   +    +   G V A   D     ++ Y I  GN  N++L+N +TG
Sbjct: 699 EPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSISKGNTDNIVLIN-STG 757

Query: 848 SMTLSPQL-NTNVPKL 862
           ++ L  ++ +  +P L
Sbjct: 758 TLYLQSEVDHEKIPSL 773



 Score =  310 bits (761), Expect = 4e-82
 Identities = 252/856 (29%), Positives = 390/856 (45%), Gaps = 59/856 (6%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +INVLD ND+ PVF  +    +V E    G+ V  + A D D G N +V Y  ++V  +T
Sbjct: 1211 EINVLDVNDNYPVFINETTFKTVPEKLPIGSVVAAVLAVDSDQGDNGKVRY--KIVNGNT 1268

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                                F+I+  +G + T  +LD E   RY + V ATD        
Sbjct: 1269 -----------------DGTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKT 1311

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
                 TI+V   D NDN P F +      + E++ +  N  +  IKA D D G NS I Y
Sbjct: 1312 SYQLVTIYVE--DANDNRPTFDKNPIITWIYENVPINTN--VTTIKAHDDDSGLNSRIWY 1367

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS---NTTQLLIN 246
             I   + +  F I+S +G +     +D E++  Y L +RA D     +    NT  L I 
Sbjct: 1368 TIDSQSPRAHFKINSETGLIQTTHPIDREEISEYSLKVRATDQAFTEQDRLYNTATLKII 1427

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            I+D+NDNAP+F  S     V E+ P  + +  + A D D G    + Y +   D TG   
Sbjct: 1428 IQDLNDNAPKF-VSRNLTYVMEDEPFNFQVTSITALDPDTGQGGNVEYRIVSPD-TGK-- 1483

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
               ++D ++G +   G LD E   +Y L ++ATD G PP ++                 F
Sbjct: 1484 --FSLDLKTGVLKLIGSLDYEDVPQYTLHISATDLGSPPLTSYQLFNVVVVDVNDNPPEF 1541

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLIT 424
                +   ++E++P GT VV +TA D D  +   L Y I  G    +FSI   +  GLI 
Sbjct: 1542 TRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELTYSIPSGVEMDKFSIDKHS--GLIV 1599

Query: 425  VAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
                LD +++  Y LTV AT      R  +  V+IN+ D N+  P F +   T  V E++
Sbjct: 1600 TNSILDREKKDTYFLTVHATGVSYPFRVSSTSVRINVMDRNDNPPKFISPVVTLKVPENS 1659

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
            P    +  ++  D D G N ++ YS+ S        + D  F I   TG ++T   LDRE
Sbjct: 1660 P-ARLIYTLTVQDLDYGNNTKVLYSIMS-------GNTDGAFTIGRSTGELSTTTKLDRE 1711

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
            T + Y L+V A+D   P  +   ++ I + D NDN PVF+Q LY++ I E    GTS+  
Sbjct: 1712 TKASYQLSVQAKDITPPYYTAFANITIFIEDQNDNPPVFQQSLYSSTISELTPPGTSILN 1771

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
            + A+D D G NG I Y L   +   G + ID  +G++ +    +      ++   +A D 
Sbjct: 1772 LTASDKDSGSNGNIVYTL--SNDTYGVYSIDSRTGIVYSAARFETSIKQEYNFFCIAKDQ 1829

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA--HDPDEGPNA 720
            G  P+ + V V IKIED N+  P F       +I  N+     +  + A   D D+  N 
Sbjct: 1830 GQDPKMAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNG 1889

Query: 721  VVHYSIKGGDDSNS-FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776
             V Y +    +S S F +E+  GS +    T        P+ ++ L I A    SPPL  
Sbjct: 1890 KVTYRLDDSKNSTSLFVVESNTGSVR----TSAGFS-NPPQGRHALYIIAEDHGSPPLRG 1944

Query: 777  DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNN 836
               V+I++ ++ D+ P   +      +  +   VG +       A    ++ Y I+SGN 
Sbjct: 1945 YGIVQIVIGNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRARASSDAQVTYSIISGNK 2004

Query: 837  ANLILLNETTGSMTLS 852
                 ++  TG ++++
Sbjct: 2005 GRAFYVDPFTGVISVA 2020



 Score =  302 bits (741), Expect = 1e-79
 Identities = 226/729 (31%), Positives = 347/729 (47%), Gaps = 58/729 (7%)

Query: 2    SVPFCIHQQINVL--DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVE 59
            S P   +Q  NV+  D ND+ P F    +  +V E   +GT+V+ + A D+D G NAE+ 
Sbjct: 1518 SPPLTSYQLFNVVVVDVNDNPPEFTRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELT 1577

Query: 60   YTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKA 119
            Y+I         P               D F ID  SG ++T + LDREK   Y + V A
Sbjct: 1578 YSI---------PSGVE----------MDKFSIDKHSGLIVTNSILDREKKDTYFLTVHA 1618

Query: 120  TDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA 179
            T  + P   R+SST ++ +N++D NDN P+F     T+ V E+   +   +I  +   D 
Sbjct: 1619 TGVSYPF--RVSST-SVRINVMDRNDNPPKFISPVVTLKVPEN---SPARLIYTLTVQDL 1672

Query: 180  DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239
            D G N+ + Y+I+ GNT   F+I   +G++S    LD E   SY+L ++A+D   P  + 
Sbjct: 1673 DYGNNTKVLYSIMSGNTDGAFTIGRSTGELSTTTKLDRETKASYQLSVQAKDITPPYYTA 1732

Query: 240  TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
               + I I D NDN P F  SL+  ++SE  P G SI+ + A D D G N  + YT+++ 
Sbjct: 1733 FANITIFIEDQNDNPPVFQQSLYSSTISELTPPGTSILNLTASDKDSGSNGNIVYTLSND 1792

Query: 300  DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
             Y        +ID R+G VY++ + +   + +Y     A D G  P+ A           
Sbjct: 1793 TYG-----VYSIDSRTGIVYSAARFETSIKQEYNFFCIAKDQGQDPKMAIVPVRIKIEDK 1847

Query: 360  XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT-----GGNTRGRFSI 414
                  F    YEV +  +      V  +TATDAD D   + ++T       N+   F +
Sbjct: 1848 NNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYRLDDSKNSTSLFVV 1907

Query: 415  TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFEN- 471
             S  G   +  +       + R+ L + A D G        +VQI I +  +  P F N 
Sbjct: 1908 ESNTGS--VRTSAGFSNPPQGRHALYIIAEDHGSPPLRGYGIVQIVIGNIQDDPPRFLNQ 1965

Query: 472  APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
             P   S+ E++ +G+ +  V A  S    +AQ+TYS+ S        +  + F ++P TG
Sbjct: 1966 TPARVSIPENSKVGSYITTVRARASS---DAQVTYSIIS-------GNKGRAFYVDPFTG 2015

Query: 532  AIT--TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589
             I+  +   LD E+   + L + A   G  SL+    ++I+V+D NDN P F      A 
Sbjct: 2016 VISVASADALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSPAFHPSNMLAQ 2075

Query: 590  IMED--ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647
            + ED  A     V +V ATD D G NG++ Y +     E G F ID  +G I T K LDR
Sbjct: 2076 LAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSI-WTGNEAGVFTIDSTTGEITTAKLLDR 2134

Query: 648  ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
            E+ A+ DL     D G PP+S+   V + + D+ND+PP+F+       I E++  G  + 
Sbjct: 2135 ETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFD-PLSEVNIREDTRTGAVVT 2193

Query: 708  EIRAHDPDE 716
             + A D D+
Sbjct: 2194 SVVATDTDK 2202



 Score =  300 bits (737), Expect = 3e-79
 Identities = 246/844 (29%), Positives = 389/844 (46%), Gaps = 58/844 (6%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I + D ND++P F  +     V E       V ++ A D D G+   VEY I  V+ DT
Sbjct: 1425 KIIIQDLNDNAPKFVSRNL-TYVMEDEPFNFQVTSITALDPDTGQGGNVEYRI--VSPDT 1481

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                                F +D ++G L    SLD E V +YT+ + ATD  SP    
Sbjct: 1482 ------------------GKFSLDLKTGVLKLIGSLDYEDVPQYTLHISATDLGSPP--- 1520

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            L+S    +V ++D NDN P+F+   +  +V E+   T   V+ K+ A D D G+N+ + Y
Sbjct: 1521 LTSYQLFNVVVVDVNDNPPEFTRDLFIGTVSEN-KPTGTSVV-KVTAYDRDSGSNAELTY 1578

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            +I  G    +FSID  SG +     LD E+  +Y L + A     P R ++T + IN+ D
Sbjct: 1579 SIPSGVEMDKFSIDKHSGLIVTNSILDREKKDTYFLTVHATGVSYPFRVSSTSVRINVMD 1638

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
             NDN P+F + +    V EN P    I  +   D D G N ++ Y++     +GN D   
Sbjct: 1639 RNDNPPKFISPVVTLKVPENSPARL-IYTLTVQDLDYGNNTKVLYSIM----SGNTDGAF 1693

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            TI   +G + T+ +LDRET+A YQL V A D   P  +A A               F   
Sbjct: 1694 TIGRSTGELSTTTKLDRETKASYQLSVQAKDITPPYYTAFANITIFIEDQNDNPPVFQQS 1753

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGN-TRGRFSITSQNGRGLITVAQP 428
             Y   ++E  PPGT ++ LTA+D D  +  +   T  N T G +SI S+ G         
Sbjct: 1754 LYSSTISELTPPGTSILNLTASDKDSGSNGNIVYTLSNDTYGVYSIDSRTGIVYSAARFE 1813

Query: 429  LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
               KQE  +           +     V+I I D NN+AP F   PY   +F +      V
Sbjct: 1814 TSIKQEYNFFCIAKDQGQDPKMAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALV 1873

Query: 489  LVVSATDSDV--GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
             +V+ATD+D     N ++TY L    ++ ++      FV+   TG++ T+          
Sbjct: 1874 TMVTATDADTDKSTNGKVTYRLDDSKNSTSL------FVVESNTGSVRTSAGFSNPPQGR 1927

Query: 547  YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT-ANIMEDALVGTSVSQVGA 605
            + L + A D G P L     V+I + ++ D+ P F  Q     +I E++ VG+ ++ V A
Sbjct: 1928 HALYIIAEDHGSPPLRGYGIVQIVIGNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRA 1987

Query: 606  TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA--LDRESVATHDLKAVAIDGG 663
              +    + ++ Y +   ++   +F +DP +GVI    A  LD ES     L  VA   G
Sbjct: 1988 RASS---DAQVTYSIISGNKGR-AFYVDPFTGVISVASADALDYESTKNFRLHLVATPQG 2043

Query: 664  TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT--IGEIRAHDPDEGPNAV 721
                +  +I+ I + D ND+ P F    +   ++E++       + ++ A D D G N  
Sbjct: 2044 WVSLNGYMILDINVIDRNDNSPAFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGK 2103

Query: 722  VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDV 778
            V YSI  G+++  F++++  G    E+ T   LD E+    ++LVIR      PP   + 
Sbjct: 2104 VTYSIWTGNEAGVFTIDSTTG----EITTAKLLDRETTAS-FDLVIRGTDSGIPPKSTNC 2158

Query: 779  RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNAN 838
            +V+++VTD+NDN P+      + N  +D         V A D D   +L Y + S +   
Sbjct: 2159 QVKVVVTDLNDNPPLFDPLSEV-NIREDTRTGAVVTSVVATDTDKESRLTYNLKSASTPG 2217

Query: 839  LILL 842
            + +L
Sbjct: 2218 IAIL 2221



 Score =  272 bits (667), Expect = 9e-71
 Identities = 260/893 (29%), Positives = 398/893 (44%), Gaps = 112/893 (12%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I + D ND+ PVF+   Y +++ E    GT++L L A+D+D G N  + YT+   + DT 
Sbjct: 1738 IFIEDQNDNPPVFQQSLYSSTISELTPPGTSILNLTASDKDSGSNGNIVYTL---SNDTY 1794

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                              V+ ID R+G + + A  +      Y     A DQ     D  
Sbjct: 1795 G-----------------VYSIDSRTGIVYSAARFETSIKQEYNFFCIAKDQGQ---DPK 1834

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV--GANSAIR 188
             +   + + I D N++ PQF++  Y V +  + S +   ++  + ATDAD     N  + 
Sbjct: 1835 MAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSAS--ALVTMVTATDADTDKSTNGKVT 1892

Query: 189  YAIIGG-NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            Y +    N+   F ++S +G V             + L I A+D GSP       + I I
Sbjct: 1893 YRLDDSKNSTSLFVVESNTGSVRTSAGFSNPPQGRHALYIIAEDHGSPPLRGYGIVQIVI 1952

Query: 248  RDVNDNAPRFYTSL-FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
             ++ D+ PRF      + S+ EN  +G  I  V+A  + +   A++TY++     +GN  
Sbjct: 1953 GNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRARASSD---AQVTYSII----SGNKG 2005

Query: 307  LPITIDPRSGW--VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
                +DP +G   V ++  LD E+   ++L + AT  G    +                 
Sbjct: 2006 RAFYVDPFTGVISVASADALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSP 2065

Query: 365  XFMPGQYEVELAEDEPPGTP--VVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGR 420
             F P     +LAED     P  VV +TATD D   + ++ Y I  GN  G F+I S  G 
Sbjct: 2066 AFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGNEAGVFTIDSTTGE 2125

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANN----YAPVFE---- 470
              IT A+ LD +    + L +  TDSG   +S    V++ +TD N+    + P+ E    
Sbjct: 2126 --ITTAKLLDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFDPLSEVNIR 2183

Query: 471  -----NAPYTASVFED--------------APIGTTVLVVSATDSDVGINAQITYSLSSE 511
                  A  T+ V  D              +  G  +L VSATD D G NAQI YS    
Sbjct: 2184 EDTRTGAVVTSVVATDTDKESRLTYNLKSASTPGIAILRVSATDQDSGSNAQIKYSFP-- 2241

Query: 512  ISNEAVAHHDQ-QFVINPQTGAITTNKLLDRETMSGYL-LTVTARDGGVPSLSDTTDVEI 569
                 + + DQ  + I+  TG I+  + +D      ++ + V A D GVP       V I
Sbjct: 2242 -----ITNSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPPQRALVYVRI 2296

Query: 570  SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN-GRIHYELDPKDREEG 628
             +      EP F+   Y   + E+A++GTSV  V  TD   GL  GRI Y ++       
Sbjct: 2297 IIT----REPKFELPSYFGKVPENAMMGTSVLTVRVTDNAAGLPLGRISYNIE----NSN 2348

Query: 629  SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688
             F I   SGVI  NK LD E+     L   AID   P +   V V+I + D+ND  PVF 
Sbjct: 2349 YFRIGQRSGVISVNKPLDYETKRRFLLVVSAIDDTAPSKPVRVPVYINVSDVNDEKPVFG 2408

Query: 689  SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAEL 748
                    SE  P+GT +  + A D D G N  V ++I+ GDD  SF+++ + G     +
Sbjct: 2409 QSGYMAQWSEGIPVGTIVVNVSAADKDSGANGRVWFAIQSGDDKGSFAIDRKTG----VI 2464

Query: 749  VTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMK-----DFQII 800
             T   LD+E+  K + + +RA    SPP+  DV V I V D+NDN PV +     D Q++
Sbjct: 2465 RTQRALDHET-IKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRVPGPNDVQVL 2523

Query: 801  FNNYKDCFPVGP-FGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMT 850
             N      P+      + A D D     +L + ++ G    L L+++ +G +T
Sbjct: 2524 EN-----LPLNSRLYEINATDRDSGANARLSFTVIGGTGQGLFLIDKFSGWLT 2571



 Score =  266 bits (651), Expect = 8e-69
 Identities = 206/691 (29%), Positives = 321/691 (46%), Gaps = 62/691 (8%)

Query: 90   FRIDGRSGALLTRAS--LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
            F +D  +G +   ++  LD E    + + + AT Q   VS  L+    + +N+ID NDN 
Sbjct: 2008 FYVDPFTGVISVASADALDYESTKNFRLHLVATPQGW-VS--LNGYMILDINVIDRNDNS 2064

Query: 148  PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
            P F        + ED        + K+ ATD D G N  + Y+I  GN    F+IDS +G
Sbjct: 2065 PAFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGNEAGVFTIDSTTG 2124

Query: 208  DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
            +++  K LD E   S+ LVIR  D G P +S   Q+ + + D+NDN P  +  L + ++ 
Sbjct: 2125 EITTAKLLDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPP-LFDPLSEVNIR 2183

Query: 268  ENVPIGYSIVRVQAYDADEGVNAELTYTM---------------TDKDYTGNVDL----P 308
            E+   G  +  V A D D+   + LTY +               TD+D   N  +    P
Sbjct: 2184 EDTRTGAVVTSVVATDTDK--ESRLTYNLKSASTPGIAILRVSATDQDSGSNAQIKYSFP 2241

Query: 309  IT--------IDPRSGWVYTSGQLDRETQAKY-QLLVTATDGGDPPRSATATXXXXXXXX 359
            IT        ID  +G +     +D   +  + Q+ V A D G PP+ A           
Sbjct: 2242 ITNSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPPQRALV----YVRII 2297

Query: 360  XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED---NRLHYEITGGNTRGRFSITS 416
                  F    Y  ++ E+   GT V+T+  TD        R+ Y I   N    F I  
Sbjct: 2298 ITREPKFELPSYFGKVPENAMMGTSVLTVRVTDNAAGLPLGRISYNIENSNY---FRIGQ 2354

Query: 417  QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ--INITDANNYAPVFENAPY 474
            ++G  +I+V +PLD++ +RR++L VSA D    S    V   IN++D N+  PVF  + Y
Sbjct: 2355 RSG--VISVNKPLDYETKRRFLLVVSAIDDTAPSKPVRVPVYINVSDVNDEKPVFGQSGY 2412

Query: 475  TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
             A   E  P+GT V+ VSA D D G N ++ +++ S             F I+ +TG I 
Sbjct: 2413 MAQWSEGIPVGTIVVNVSAADKDSGANGRVWFAIQS-------GDDKGSFAIDRKTGVIR 2465

Query: 535  TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ-LYTANIMED 593
            T + LD ET+  + ++V A D G P +     V I V+D+NDN PVF+        ++E+
Sbjct: 2466 TQRALDHETIKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRVPGPNDVQVLEN 2525

Query: 594  ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653
              + + + ++ ATD D G N R+ + +      +G F+ID  SG + TN   D E+ A +
Sbjct: 2526 LPLNSRLYEINATDRDSGANARLSFTVIG-GTGQGLFLIDKFSGWLTTNITFDYENTAVY 2584

Query: 654  D--LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711
               L   A D G PP SS + + + + D ++  P F      F +  N+ IG  +G++ A
Sbjct: 2585 QYSLTIKATDAGNPPLSSNITIIVNVADEDEYDPSFNRMDYKFDVPGNAKIGDFVGQVTA 2644

Query: 712  HDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
             D D G    V + +     SN+  +    G
Sbjct: 2645 TDRDSGDQGRVFF-VFYNPTSNALKMNATTG 2674



 Score =  242 bits (592), Expect = 1e-61
 Identities = 251/933 (26%), Positives = 396/933 (42%), Gaps = 96/933 (10%)

Query: 1    MSVPFCIHQ---QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAE 57
            +S PF +     +INV+D ND+ P F        V E  S    + TL   D D G N +
Sbjct: 1621 VSYPFRVSSTSVRINVMDRNDNPPKFISPVVTLKVPEN-SPARLIYTLTVQDLDYGNNTK 1679

Query: 58   VEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLV 117
            V Y+I     D                     F I   +G L T   LDRE  A Y + V
Sbjct: 1680 VLYSIMSGNTD-------------------GAFTIGRSTGELSTTTKLDRETKASYQLSV 1720

Query: 118  KATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKAT 177
            +A D   P     ++ A I + I D NDN P F +  Y+ ++ E         I  + A+
Sbjct: 1721 QAKDITPPY---YTAFANITIFIEDQNDNPPVFQQSLYSSTISE--LTPPGTSILNLTAS 1775

Query: 178  DADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237
            D D G+N  I Y +   +T   +SIDS +G V      +    + Y     A+D G   +
Sbjct: 1776 DKDSGSNGNIVYTL-SNDTYGVYSIDSRTGIVYSAARFETSIKQEYNFFCIAKDQGQDPK 1834

Query: 238  SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD--EGVNAELTYT 295
                 + I I D N++AP+F  + ++  +  N      +  V A DAD  +  N ++TY 
Sbjct: 1835 MAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYR 1894

Query: 296  MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355
            + D   + ++     ++  +G V TS       Q ++ L + A D G PP          
Sbjct: 1895 LDDSKNSTSL---FVVESNTGSVRTSAGFSNPPQGRHALYIIAEDHGSPPLRGYGIVQIV 1951

Query: 356  XXXXXXXXXXFM-PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSI 414
                      F+      V + E+   G+ + T+ A  A  D ++ Y I  GN    F +
Sbjct: 1952 IGNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRAR-ASSDAQVTYSIISGNKGRAFYV 2010

Query: 415  TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENA 472
                G   +  A  LD++  + + L + AT  G  S     ++ IN+ D N+ +P F  +
Sbjct: 2011 DPFTGVISVASADALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSPAFHPS 2070

Query: 473  PYTASVFEDAPIGTT--VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
               A + ED        V+ V+ATD D G N ++TYS+ +   NEA       F I+  T
Sbjct: 2071 NMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWT--GNEAGV-----FTIDSTT 2123

Query: 531  GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV-------------DVNDN 577
            G ITT KLLDRET + + L +   D G+P  S    V++ V              +VN  
Sbjct: 2124 GEITTAKLLDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFDPLSEVNIR 2183

Query: 578  EPVF--------------KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK 623
            E                 K+   T N+   +  G ++ +V ATD D G N +I Y     
Sbjct: 2184 EDTRTGAVVTSVVATDTDKESRLTYNLKSASTPGIAILRVSATDQDSGSNAQIKYSFPIT 2243

Query: 624  DREEGSFVIDPASGVIRTNKALD-RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND 682
            + ++  + ID  +GVI   + +D R   +   +   A+D G PPQ + V V I    I  
Sbjct: 2244 NSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPPQRALVYVRI----IIT 2299

Query: 683  SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG-PNAVVHYSIKGGDDSNSFSLETRQ 741
              P FE       + EN+ +GT++  +R  D   G P   + Y+I   ++SN F +  R 
Sbjct: 2300 REPKFELPSYFGKVPENAMMGTSVLTVRVTDNAAGLPLGRISYNI---ENSNYFRIGQRS 2356

Query: 742  GSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQ 798
            G     +     LDYE+ ++++ LV+ A    +P     V V I V+DVND  PV     
Sbjct: 2357 G----VISVNKPLDYET-KRRFLLVVSAIDDTAPSKPVRVPVYINVSDVNDEKPVFGQSG 2411

Query: 799  IIFNNYKDCFPVGPF-GRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQL 855
             +   + +  PVG     V A D D     ++ + I SG++     ++  TG +     L
Sbjct: 2412 YM-AQWSEGIPVGTIVVNVSAADKDSGANGRVWFAIQSGDDKGSFAIDRKTGVIRTQRAL 2470

Query: 856  NTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLI 887
            +    K   + V  TD G   +   + +++R++
Sbjct: 2471 DHETIKTHHVSVRATDEGSPPMHTDVSVTIRVL 2503



 Score =  227 bits (554), Expect = 4e-57
 Identities = 172/587 (29%), Positives = 276/587 (47%), Gaps = 34/587 (5%)

Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
           +P  ++  +G + T   LDRE  + Y L  T  +   PP+S T                F
Sbjct: 3   IPADLEYNAGVITTKTVLDREKVSAYNL--TIVEFSTPPKSYTV--LVYVQDLNDNSPSF 58

Query: 367 MPG-QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG------ 419
           + G   ++ + E++      +    +D   ++   Y I  GN    F + S+        
Sbjct: 59  VRGTSAKLVVFENDKDFRQKLIAVDSDFGSNSTQSYTIVSGNVGNVFKLISKRDTDGDLY 118

Query: 420 RGLITVAQPLDFKQER--RYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYT 475
             L+  A  +   +ER   YVL +SA+D G  ++   ++++IT  D N+  P F N  Y+
Sbjct: 119 ADLVVNASSIGVDRERLDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVSYS 178

Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
            ++ E+  +GT++L VSA+D D+G NA+I YS+ +    +A+      F I+P TG I  
Sbjct: 179 GTIPENIDVGTSILQVSASDKDIGTNAEIQYSIETHSDPQAI------FGIHPTTGVIVN 232

Query: 536 NKLLDRETMSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA----NI 590
           N  LD E    YL+ V A D G    LS +  V I V+DVNDN PV     YT      +
Sbjct: 233 NVRLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVS-YTLGGSYQV 291

Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNKALDRES 649
            E+A +GT V++V  +DAD G NG ++  L+  D      F +     +I   ++LDRE+
Sbjct: 292 TENATIGTQVARVSVSDADSGKNGEVNVTLEGGDGYFSMKFDVLNDESIIAVGQSLDRET 351

Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
                LKAV ID G PP+++     I + D+ND  P F+       + EN+ + T +  +
Sbjct: 352 HDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIV 411

Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES-PRKKYELVIR 768
            A D D G N+ + Y+I    +S S+            + T  DLD E  P+    +++ 
Sbjct: 412 NAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQVVLTVLVH 471

Query: 769 -AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK- 826
              SPPL ++  V + +TD NDN P         + +++     P  ++ A D D+ +  
Sbjct: 472 DRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENS 531

Query: 827 -LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            + Y IL+ N      L+   G +T S  L+  V    T +V+ TDG
Sbjct: 532 LILYSILTPNTP--FFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDG 576


>UniRef50_UPI00015A700B Cluster: UPI00015A700B related cluster; n=1;
            Danio rerio|Rep: UPI00015A700B UniRef100 entry - Danio
            rerio
          Length = 3528

 Score =  378 bits (931), Expect = e-103
 Identities = 250/804 (31%), Positives = 411/804 (51%), Gaps = 67/804 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I+V+D ND+SPV  M  +   ++E + +GT V  +   D D GKN +V   +E  +  T+
Sbjct: 927  IDVVDVNDNSPVISMTSFSGKIQEDSPAGTVVALISVQDLDSGKNGQVRLALEQSSPFTI 986

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             P                          L+T A LDREKV+ + + + ATD+ SP    L
Sbjct: 987  KPSPRKYYT-------------------LVTDAPLDREKVSSFNLTLVATDEGSP---SL 1024

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             S  TI +++ D NDN P FS++ Y   V E+ S      +  ++A+D D G N+ I Y 
Sbjct: 1025 FSKITISLDVTDINDNAPVFSQREYKAYVMENNS--PGVSLLTLQASDPDAGQNARIAYY 1082

Query: 191  II-----GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
            +I     G      FS+++ +G +  V++ DYEQ++ +++ +RAQDGGSP   +   ++I
Sbjct: 1083 LIDSDVNGSPVSSHFSVNADNGIIHAVRSFDYEQMKEFKIHVRAQDGGSPPLCSNATVVI 1142

Query: 246  NIRDVNDNAPRFY------TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
            N++D NDNAP+         S+  E V  +  +GY + +V A D D G NA L+Y +   
Sbjct: 1143 NVQDQNDNAPQVLYPVQSGASVVAEIVPRSADVGYLVTKVVAVDVDSGQNAWLSYKL--- 1199

Query: 300  DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
             +         +  ++G + T  Q   +     +L+  A DGG+P RS +          
Sbjct: 1200 -HKATDRALFEVGAQNGEIRTVRQESADDHDSLKLI--AVDGGNPQRSGSVIIDVTVLDA 1256

Query: 360  XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEI--TGGNTRGRFSIT 415
                  F    Y   + E+ P GT + T+ ATDAD  +  R+ Y      G     F+I 
Sbjct: 1257 NDNAPVFNQTVYRASVMENAPKGTYITTVNATDADAGSYGRITYNFYKQKGAAAQLFNID 1316

Query: 416  SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYT 475
            S  G  +I+V   +D +++ ++ LTV A D GG +D++ + +++ D N+ APV     ++
Sbjct: 1317 SNTG--IISVVGEIDHEKDTKFELTVEARDQGGLTDSSKITLDVIDVNDNAPVINAMSFS 1374

Query: 476  ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
            ++V EDAP  TT+ +++  D+D   N ++  S   E S + V     +        ++ T
Sbjct: 1375 STVSEDAPPDTTIAIINVKDADTDDNGRV--SCFIEGSEDFVVKSTLR-----NYYSLVT 1427

Query: 536  NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
            N +LDRE +S Y +TV A D G P L+      + VVDVNDN PVF++++Y + + E+  
Sbjct: 1428 NVILDREKLSEYNITVVATDSGKPPLTSRKTFNLKVVDVNDNAPVFRERVYNSYLPENNS 1487

Query: 596  VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV-IDPASGVIRTNKALDRESVATHD 654
             G S+ ++ A D D   N RI Y L+  D   G++V ++  SGV+   ++ D E +    
Sbjct: 1488 PGVSILRIRAHDPDENQNARISYILEESDL--GTYVSVNAESGVVHAVRSFDYEQIKNIK 1545

Query: 655  LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
            +   A DGG+PP SS V + + + D+ND+ PVF        ++EN+P GT I  + A D 
Sbjct: 1546 VTVKAQDGGSPPLSSNVTIDVTVLDVNDNAPVFNQTVYRASVTENAPKGTYITTVNATDA 1605

Query: 715  DEGPNAVVHYSIKGGDDSNS--FSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRAAS 771
            D G N  +  S     + +   F+++   G     LV+++ ++D+E   K++E+ ++A  
Sbjct: 1606 DSGSNGHITLSFSDLKEQSRGIFNIDENTG-----LVSVLGNIDFEKD-KRFEIRVKATD 1659

Query: 772  P-PLWNDVRVEILVTDVNDNAPVM 794
               L +  ++ I V DVNDNAPV+
Sbjct: 1660 QGGLTSTSKLIIEVVDVNDNAPVI 1683



 Score =  375 bits (923), Expect = e-102
 Identities = 263/806 (32%), Positives = 404/806 (50%), Gaps = 63/806 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVR-EGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            + + D ND++PVFE   Y+ASV+ E A +G  V+ + ATD D G N E+ Y+    +   
Sbjct: 2759 LQISDVNDNAPVFEQSSYQASVQFENAPNGAVVVRVSATDNDQGANGEITYSFSRSSGKN 2818

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            L                 D+F I   +G +  +  LD E+  ++ + + ATD+       
Sbjct: 2819 L-----------------DLFHIGPDTGEITVKGHLDYERAKQFELNIDATDKGG----- 2856

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            L+ ++ + ++I D NDN P  S  +++  + ED +     VIA +   D D G N  ++ 
Sbjct: 2857 LTDSSKVIIDITDVNDNPPVISLISFSNPIPEDAA--PETVIAMLNVKDLDSGKNGQVKC 2914

Query: 190  AIIGGNTQMQFSIDSLSGDV-SLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
             I   +  M F + S + +  SL+  + LD E++  Y + + A D GSPS S    L + 
Sbjct: 2915 YI---SADMPFKVKSSAQNFYSLITDQLLDREKISEYNITVTATDEGSPSFSTNKTLTLK 2971

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            I DVNDNAP F    +   + EN   G S++ V+A+D D G NA ++Y +         D
Sbjct: 2972 ISDVNDNAPVFERQSYTAFIIENNSPGVSVLSVKAHDRDSGNNARISYFLDLSGSEHGND 3031

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
                ++     +     LDRETQ +++L +TA DGG+P R+ T                F
Sbjct: 3032 GSKYVE-----MVLQAPLDRETQHEHKLTLTAFDGGNPQRTGTVRICVTVIDANDNAPVF 3086

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEIT--GGNTRGRFSITSQNGR-- 420
                Y V L E+ P G  VV ++ATD D+  +  + Y  +   G     F I +  G   
Sbjct: 3087 SLPVYRVSLFENAPNGAVVVRVSATDNDQGANGEITYSFSRSSGKNLDLFHIGADTGEIT 3146

Query: 421  ---GLITVAQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYT 475
                LIT  Q LD ++   Y +TV+ATD G  S +    + + I+D N+ APVFE   YT
Sbjct: 3147 NFYSLIT-DQLLDREKISEYNITVTATDEGSPSFSTNKTLTLKISDVNDNAPVFERQSYT 3205

Query: 476  ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV-INPQTGAIT 534
            A + E+   G +VL V A D D G NA+I+Y L   + N   A     F+ +N ++G I 
Sbjct: 3206 AFIMENNSPGVSVLSVKAHDRDSGNNARISYFLEDVVVNGVSA---STFISVNAESGEIL 3262

Query: 535  TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
              +  D E    + + V A+DGG P LS  +++ + V+D NDN P F Q +Y A+I E+ 
Sbjct: 3263 AARSFDYEQTKDFSIRVKAQDGGSPPLS--SNINVIVLDANDNAPAFSQSVYKASIPENF 3320

Query: 595  LVGTSVSQVGATDADVGLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNKA---LDRESV 650
              G+SV +V A D D G NG + Y L        G F ID  +G I  N     LDRE +
Sbjct: 3321 SKGSSVLKVSAADGDTGSNGEVTYSLSQSSESFSGLFNIDSNTGDITVNVTDDLLDREML 3380

Query: 651  ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710
            + +++   A D G+P  S+   + +KI D+ND+ PVFE    T +I EN+  G ++  ++
Sbjct: 3381 SEYNITVTATDEGSPSFSTNKTLTLKISDVNDNAPVFERQSYTAFIMENNSPGVSVLSVK 3440

Query: 711  AHDPDEGPNAVVHYSIKG-GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
            AHD D G NA + Y ++    +  S S      ++  E++     DYE   K + + ++A
Sbjct: 3441 AHDRDSGNNARISYFLEDVVVNGVSASTFISVHAESGEILAARSFDYEQ-TKDFSIRVKA 3499

Query: 770  ---ASPPLWNDVRVEILVTDVNDNAP 792
                SPPL ++V V+IL+ D NDNAP
Sbjct: 3500 QDGGSPPLSSNVSVKILIQDQNDNAP 3525



 Score =  375 bits (922), Expect = e-101
 Identities = 272/888 (30%), Positives = 429/888 (48%), Gaps = 69/888 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I++ D ND++PVFE   Y+ASV+  A  G  V  + A D D G+NA + Y +   T   L
Sbjct: 2008 IDISDVNDNAPVFEQSSYQASVQRSADVGYLVTKVVAVDVDSGQNAWLSYKLHKATDRAL 2067

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLT--RASLDREKVARYTVLVKATDQASPVSD 128
                               F +  ++G + T  +  LDREK     +++ A D   P   
Sbjct: 2068 -------------------FEVGAQNGEIRTVRQKPLDREKQNEINLVLTAVDGGDP--- 2105

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            +LS +  IH+ ++D NDN P F +  Y  +V E+     + +++ + ATDAD G NS I 
Sbjct: 2106 QLSGSIDIHITVLDANDNAPVFMQSVYKATVTEN--APKDTIVSTVSATDADEGINSKIE 2163

Query: 189  YAIIG--GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT-TQLLI 245
            Y+I     N +  F I+  +G V +V  +D+E+ R+Y + ++A D  S S+S   T++++
Sbjct: 2164 YSIANRQDNVRQLFDINKDNGQVRVVGIIDFEKARNYEISVQASDHLSGSKSEPLTEVIL 2223

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK-DYTGN 304
               D NDNAP    ++++ S++EN P G  +  V A DAD+G N+ +T++++   D   +
Sbjct: 2224 EFLDANDNAPVCSQTVYKTSIAENSPKGTVLTTVSASDADQGSNSRITFSISSTADKAAD 2283

Query: 305  VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
            +     ID   G V  +G +D E +      + + DGGDP  S +               
Sbjct: 2284 I---FEIDSELGVVKLTGGIDYEQRHSLLTDIRSVDGGDPQLSGSIDIHITVLDVNDNAP 2340

Query: 365  XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGL 422
             FM   Y+  + E+ P  T V T++ATDADE  ++++ Y I   +     SI S   R L
Sbjct: 2341 VFMQSVYKATVTENAPKDTIVSTVSATDADEGINSKIEYSIANIDNGQSVSIQSYYSREL 2400

Query: 423  ITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFE 480
                     + + + +L  +A D G    S TA + I + DAN+ APVF    Y AS+ E
Sbjct: 2401 -----GKGHRVDHKNILYKNAIDGGDPQLSGTAQIHITVLDANDNAPVFTQKIYKASITE 2455

Query: 481  DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
            +A  GT +  VSA+D D G   +ITY++++ + +  V      F IN   G +     +D
Sbjct: 2456 NAVRGTVITTVSASDLDEGSYGKITYAITNTLDDVPVL-----FEINETNGEVRVIGTVD 2510

Query: 541  RETMSGYLLTVTARDGG--VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
             E    Y + V A D G    S     D+ I+V+D NDN PVF  ++Y A+I E+A+ GT
Sbjct: 2511 YEKARHYQIHVQASDDGGLTDSCKIDVDIHITVLDANDNAPVFTHKIYKASITENAVRGT 2570

Query: 599  SVSQVGATDADVGLNGRIHYEL-DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
             ++ V A+D D G  G+I Y + +        F I+  +G I+T + +            
Sbjct: 2571 IITTVTASDLDEGSYGKITYAITNSLGNFPMLFEINETNGEIQTREKMITLENPMEFYSI 2630

Query: 658  VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
             A+DGG P  S T+ + I +ED ND+ P+         ++ENSP GT +  ++A D D+G
Sbjct: 2631 TAVDGGDPQLSGTIPIIITVEDANDNAPICFMSVYKTSVAENSPKGTVLTTVKASDADQG 2690

Query: 718  PNAVVHYSI--KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW 775
             N  V Y I    G   N F ++   G  K       D+DYE   K Y++ ++A  P   
Sbjct: 2691 QNGKVEYHIAKSTGGTINLFEIDRNAGVLKLS----GDIDYEKV-KHYQIDVQARDPGRH 2745

Query: 776  ND-------VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDAD--VTD 825
            +D       V + + ++DVNDNAPV +      +   +  P G    RV A D D     
Sbjct: 2746 SDTCKSINSVTLSLQISDVNDNAPVFEQSSYQASVQFENAPNGAVVVRVSATDNDQGANG 2805

Query: 826  KLQYRIL--SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            ++ Y     SG N +L  +   TG +T+   L+    K   + +  TD
Sbjct: 2806 EITYSFSRSSGKNLDLFHIGPDTGEITVKGHLDYERAKQFELNIDATD 2853



 Score =  372 bits (914), Expect = e-100
 Identities = 261/804 (32%), Positives = 399/804 (49%), Gaps = 54/804 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I VLD ND++PVF  + Y+AS+ E A  GT + T+ A+D D G   ++ Y I     +TL
Sbjct: 2432 ITVLDANDNAPVFTQKIYKASITENAVRGTVITTVSASDLDEGSYGKITYAI----TNTL 2487

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +              V  +F I+  +G +    ++D EK   Y + V+A+D    ++D  
Sbjct: 2488 DD-------------VPVLFEINETNGEVRVIGTVDYEKARHYQIHVQASDDGG-LTDSC 2533

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
                 IH+ ++D NDN P F+ K Y  S+ E+       +I  + A+D D G+   I YA
Sbjct: 2534 KIDVDIHITVLDANDNAPVFTHKIYKASITEN--AVRGTIITTVTASDLDEGSYGKITYA 2591

Query: 191  IIG--GNTQMQFSIDSLSGDVSL-VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            I    GN  M F I+  +G++    K +  E    +   I A DGG P  S T  ++I +
Sbjct: 2592 ITNSLGNFPMLFEINETNGEIQTREKMITLENPMEF-YSITAVDGGDPQLSGTIPIIITV 2650

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
             D NDNAP  + S+++ SV+EN P G  +  V+A DAD+G N ++ Y +  K   G ++L
Sbjct: 2651 EDANDNAPICFMSVYKTSVAENSPKGTVLTTVKASDADQGQNGKVEYHIA-KSTGGTINL 2709

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG---DPPRSATA-TXXXXXXXXXXXX 363
               ID  +G +  SG +D E    YQ+ V A D G   D  +S  + T            
Sbjct: 2710 -FEIDRNAGVLKLSGDIDYEKVKHYQIDVQARDPGRHSDTCKSINSVTLSLQISDVNDNA 2768

Query: 364  XXFMPGQYEVELA-EDEPPGTPVVTLTATDADE--DNRLHYEIT--GGNTRGRFSITSQN 418
              F    Y+  +  E+ P G  VV ++ATD D+  +  + Y  +   G     F I    
Sbjct: 2769 PVFEQSSYQASVQFENAPNGAVVVRVSATDNDQGANGEITYSFSRSSGKNLDLFHIGPDT 2828

Query: 419  GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASV 478
            G   ITV   LD+++ +++ L + ATD GG +D++ V I+ITD N+  PV     ++  +
Sbjct: 2829 GE--ITVKGHLDYERAKQFELNIDATDKGGLTDSSKVIIDITDVNDNPPVISLISFSNPI 2886

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             EDA   T + +++  D D G N Q+   +S+++  + V    Q F       ++ T++L
Sbjct: 2887 PEDAAPETVIAMLNVKDLDSGKNGQVKCYISADMPFK-VKSSAQNFY------SLITDQL 2939

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            LDRE +S Y +TVTA D G PS S    + + + DVNDN PVF++Q YTA I+E+   G 
Sbjct: 2940 LDREKISEYNITVTATDEGSPSFSTNKTLTLKISDVNDNAPVFERQSYTAFIIENNSPGV 2999

Query: 599  SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
            SV  V A D D G N RI Y LD    E G+        V++    LDRE+   H L   
Sbjct: 3000 SVLSVKAHDRDSGNNARISYFLDLSGSEHGNDGSKYVEMVLQA--PLDRETQHEHKLTLT 3057

Query: 659  AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
            A DGG P ++ TV + + + D ND+ PVF        + EN+P G  +  + A D D+G 
Sbjct: 3058 AFDGGNPQRTGTVRICVTVIDANDNAPVFSLPVYRVSLFENAPNGAVVVRVSATDNDQGA 3117

Query: 719  NAVVHYSIKGGDDSN----SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---AS 771
            N  + YS       N        +T + ++   L+T   LD E    +Y + + A    S
Sbjct: 3118 NGEITYSFSRSSGKNLDLFHIGADTGEITNFYSLITDQLLDREK-ISEYNITVTATDEGS 3176

Query: 772  PPLWNDVRVEILVTDVNDNAPVMK 795
            P    +  + + ++DVNDNAPV +
Sbjct: 3177 PSFSTNKTLTLKISDVNDNAPVFE 3200



 Score =  365 bits (899), Expect = 7e-99
 Identities = 261/802 (32%), Positives = 399/802 (49%), Gaps = 57/802 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I VLD ND++PVF    Y+A+V E A   T V T+ ATD D G N+++EY+I        
Sbjct: 2115 ITVLDANDNAPVFMQSVYKATVTENAPKDTIVSTVSATDADEGINSKIEYSIA------- 2167

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N +D           V+ +F I+  +G +     +D EK   Y + V+A+D  S    + 
Sbjct: 2168 NRQD----------NVRQLFDINKDNGQVRVVGIIDFEKARNYEISVQASDHLS--GSKS 2215

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
                 + +  +D NDN P  S+  Y  S+ E+       V+  + A+DAD G+NS I ++
Sbjct: 2216 EPLTEVILEFLDANDNAPVCSQTVYKTSIAENSP--KGTVLTTVSASDADQGSNSRITFS 2273

Query: 191  IIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            I     +    F IDS  G V L   +DYEQ  S    IR+ DGG P  S +  + I + 
Sbjct: 2274 ISSTADKAADIFEIDSELGVVKLTGGIDYEQRHSLLTDIRSVDGGDPQLSGSIDIHITVL 2333

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            DVNDNAP F  S+++ +V+EN P    +  V A DADEG+N+++ Y++       N+D  
Sbjct: 2334 DVNDNAPVFMQSVYKATVTENAPKDTIVSTVSATDADEGINSKIEYSI------ANIDNG 2387

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
             ++  +S +    G+  R    K  L   A DGGDP  S TA               F  
Sbjct: 2388 QSVSIQSYYSRELGKGHR-VDHKNILYKNAIDGGDPQLSGTAQIHITVLDANDNAPVFTQ 2446

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITG--GNTRGRFSITSQNGRGLIT 424
              Y+  + E+   GT + T++A+D DE +  ++ Y IT    +    F I   NG   + 
Sbjct: 2447 KIYKASITENAVRGTVITTVSASDLDEGSYGKITYAITNTLDDVPVLFEINETNGE--VR 2504

Query: 425  VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINI----TDANNYAPVFENAPYTASVFE 480
            V   +D+++ R Y + V A+D GG +D+  + ++I     DAN+ APVF +  Y AS+ E
Sbjct: 2505 VIGTVDYEKARHYQIHVQASDDGGLTDSCKIDVDIHITVLDANDNAPVFTHKIYKASITE 2564

Query: 481  DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKLL 539
            +A  GT +  V+A+D D G   +ITY++++ + N         F IN   G I T  K++
Sbjct: 2565 NAVRGTIITTVTASDLDEGSYGKITYAITNSLGN-----FPMLFEINETNGEIQTREKMI 2619

Query: 540  DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
              E    +  ++TA DGG P LS T  + I+V D NDN P+    +Y  ++ E++  GT 
Sbjct: 2620 TLENPMEF-YSITAVDGGDPQLSGTIPIIITVEDANDNAPICFMSVYKTSVAENSPKGTV 2678

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREE-GSFVIDPASGVIRTNKALDRESVATHDLKAV 658
            ++ V A+DAD G NG++ Y +          F ID  +GV++ +  +D E V  + +   
Sbjct: 2679 LTTVKASDADQGQNGKVEYHIAKSTGGTINLFEIDRNAGVLKLSGDIDYEKVKHYQIDVQ 2738

Query: 659  AIDGG----TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS-ENSPIGTTIGEIRAHD 713
            A D G    T    ++V + ++I D+ND+ PVFE       +  EN+P G  +  + A D
Sbjct: 2739 ARDPGRHSDTCKSINSVTLSLQISDVNDNAPVFEQSSYQASVQFENAPNGAVVVRVSATD 2798

Query: 714  PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP- 772
             D+G N  + YS       N        G D  E+     LDYE   K++EL I A    
Sbjct: 2799 NDQGANGEITYSFSRSSGKNLDLFHI--GPDTGEITVKGHLDYER-AKQFELNIDATDKG 2855

Query: 773  PLWNDVRVEILVTDVNDNAPVM 794
             L +  +V I +TDVNDN PV+
Sbjct: 2856 GLTDSSKVIIDITDVNDNPPVI 2877



 Score =  363 bits (894), Expect = 3e-98
 Identities = 269/862 (31%), Positives = 417/862 (48%), Gaps = 69/862 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + VLD ND++PVF    Y ASV E A  GT + T+ ATD D G N  +          TL
Sbjct: 1566 VTVLDVNDNAPVFNQTVYRASVTENAPKGTYITTVNATDADSGSNGHI----------TL 1615

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +  D            + +F ID  +G +    ++D EK  R+ + VKATDQ       L
Sbjct: 1616 SFSDLKEQS-------RGIFNIDENTGLVSVLGNIDFEKDKRFEIRVKATDQGG-----L 1663

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDED------ISV-----TDNPVIAKIKATDA 179
            +ST+ + + ++D NDN P  +  + +  V ED      I+V     T    I  + A D 
Sbjct: 1664 TSTSKLIIEVVDVNDNAPVITLMSLSSPVSEDAPPGTTIAVLIENNTPGLSICSVTARDL 1723

Query: 180  DVGANSAIRY-----AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS 234
            D   NS + Y      I G       SI++ +G +  V++ DYEQV+ +  +++AQDGGS
Sbjct: 1724 DWNQNSRVSYYLEDAHISGVPISSYVSINAENGVLHAVRSFDYEQVKQFSFIVKAQDGGS 1783

Query: 235  P--SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292
            P  S +    + I + D NDNAP F  S+++ +V+EN P    +  V A DADEG+N+++
Sbjct: 1784 PPLSSNKFIDIHITVLDANDNAPVFMQSVYKATVTENAPKDTIVSTVSATDADEGINSKI 1843

Query: 293  TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352
             Y++ + +   +V     I+  +G V   G +D E    Y++ V A+D G       +  
Sbjct: 1844 EYSIANME--DDVQRLFAINRDNGQVSVVGIIDFERARNYEIRVQASDQGG---LTDSYI 1898

Query: 353  XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI--TGGNT 408
                         F    Y+  + E+ P GT V T++A+D D+  +  + Y I  T    
Sbjct: 1899 NIIVLDANDNAPVFSQTVYKTAVTENSPKGTIVTTVSASDLDQGVNGEITYSIRNTIDKV 1958

Query: 409  RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMV---QINITDANNY 465
            R  F I+  +G+  + +   +D++Q R + + V A+D GG +D+  +    I+I+D N+ 
Sbjct: 1959 RDIFEISETDGK--VRLIGLVDYEQARNFEIRVQASDHGGFTDSCKIIVDVIDISDVNDN 2016

Query: 466  APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525
            APVFE + Y ASV   A +G  V  V A D D G NA ++Y L  + ++ A+      F 
Sbjct: 2017 APVFEQSSYQASVQRSADVGYLVTKVVAVDVDSGQNAWLSYKL-HKATDRAL------FE 2069

Query: 526  INPQTGAITT--NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583
            +  Q G I T   K LDRE  +   L +TA DGG P LS + D+ I+V+D NDN PVF Q
Sbjct: 2070 VGAQNGEIRTVRQKPLDREKQNEINLVLTAVDGGDPQLSGSIDIHITVLDANDNAPVFMQ 2129

Query: 584  QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFVIDPASGVIRTN 642
             +Y A + E+A   T VS V ATDAD G+N +I Y + + +D     F I+  +G +R  
Sbjct: 2130 SVYKATVTENAPKDTIVSTVSATDADEGINSKIEYSIANRQDNVRQLFDINKDNGQVRVV 2189

Query: 643  KALDRESVATHDLKAVAID--GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700
              +D E    +++   A D   G+  +  T ++ ++  D ND+ PV         I+ENS
Sbjct: 2190 GIIDFEKARNYEISVQASDHLSGSKSEPLTEVI-LEFLDANDNAPVCSQTVYKTSIAENS 2248

Query: 701  PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760
            P GT +  + A D D+G N+ + +SI    D  +   E        +L   +D +     
Sbjct: 2249 PKGTVLTTVSASDADQGSNSRITFSISSTADKAADIFEIDSELGVVKLTGGIDYEQRHSL 2308

Query: 761  KKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD 820
                  +    P L   + + I V DVNDNAPV           ++         V A D
Sbjct: 2309 LTDIRSVDGGDPQLSGSIDIHITVLDVNDNAPVFMQSVYKATVTENAPKDTIVSTVSATD 2368

Query: 821  AD--VTDKLQYRILSGNNANLI 840
            AD  +  K++Y I + +N   +
Sbjct: 2369 ADEGINSKIEYSIANIDNGQSV 2390



 Score =  361 bits (889), Expect = 1e-97
 Identities = 272/813 (33%), Positives = 397/813 (48%), Gaps = 70/813 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND++P+  M  Y+ SV E +  GT + T+KA+D D G+N +VEY I   T  T+
Sbjct: 2648 ITVEDANDNAPICFMSVYKTSVAENSPKGTVLTTVKASDADQGQNGKVEYHIAKSTGGTI 2707

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N                 +F ID  +G L     +D EKV  Y + V+A D     SD  
Sbjct: 2708 N-----------------LFEIDRNAGVLKLSGDIDYEKVKHYQIDVQARDPGRH-SDTC 2749

Query: 131  SS--TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             S  + T+ + I D NDN P F + +Y  SV  + +  +  V+ ++ ATD D GAN  I 
Sbjct: 2750 KSINSVTLSLQISDVNDNAPVFEQSSYQASVQFE-NAPNGAVVVRVSATDNDQGANGEIT 2808

Query: 189  YAII--GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            Y+     G     F I   +G++++   LDYE+ + + L I A D G    +++++++I+
Sbjct: 2809 YSFSRSSGKNLDLFHIGPDTGEITVKGHLDYERAKQFELNIDATDKGG--LTDSSKVIID 2866

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            I DVNDN P      F   + E+      I  +   D D G N ++      K Y  + D
Sbjct: 2867 ITDVNDNPPVISLISFSNPIPEDAAPETVIAMLNVKDLDSGKNGQV------KCYI-SAD 2919

Query: 307  LPITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
            +P  +   +   Y   T   LDRE  ++Y + VTATD G P  S   T            
Sbjct: 2920 MPFKVKSSAQNFYSLITDQLLDREKISEYNITVTATDEGSPSFSTNKTLTLKISDVNDNA 2979

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEIT-GGNTRGRFSITSQNGR 420
              F    Y   + E+  PG  V+++ A D D  N  R+ Y +   G+  G     +   +
Sbjct: 2980 PVFERQSYTAFIIENNSPGVSVLSVKAHDRDSGNNARISYFLDLSGSEHG-----NDGSK 3034

Query: 421  GLITVAQ-PLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTAS 477
             +  V Q PLD + +  + LT++A D G    T  V+I +T  DAN+ APVF    Y  S
Sbjct: 3035 YVEMVLQAPLDRETQHEHKLTLTAFDGGNPQRTGTVRICVTVIDANDNAPVFSLPVYRVS 3094

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT--- 534
            +FE+AP G  V+ VSATD+D G N +ITYS S          H     I   TG IT   
Sbjct: 3095 LFENAPNGAVVVRVSATDNDQGANGEITYSFSRSSGKNLDLFH-----IGADTGEITNFY 3149

Query: 535  ---TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
               T++LLDRE +S Y +TVTA D G PS S    + + + DVNDN PVF++Q YTA IM
Sbjct: 3150 SLITDQLLDREKISEYNITVTATDEGSPSFSTNKTLTLKISDVNDNAPVFERQSYTAFIM 3209

Query: 592  EDALVGTSVSQVGATDADVGLNGRIHYELDP---KDREEGSFV-IDPASGVIRTNKALDR 647
            E+   G SV  V A D D G N RI Y L+          +F+ ++  SG I   ++ D 
Sbjct: 3210 ENNSPGVSVLSVKAHDRDSGNNARISYFLEDVVVNGVSASTFISVNAESGEILAARSFDY 3269

Query: 648  ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
            E      ++  A DGG+PP SS   +++ + D ND+ P F        I EN   G+++ 
Sbjct: 3270 EQTKDFSIRVKAQDGGSPPLSSN--INVIVLDANDNAPAFSQSVYKASIPENFSKGSSVL 3327

Query: 708  EIRAHDPDEGPNAVVHYSIKGGDDSNS--FSLETRQGSDKAELVTMVDLDYESPRKKYEL 765
            ++ A D D G N  V YS+    +S S  F++++  G D    VT   LD E    +Y +
Sbjct: 3328 KVSAADGDTGSNGEVTYSLSQSSESFSGLFNIDSNTG-DITVNVTDDLLDREM-LSEYNI 3385

Query: 766  VIRA---ASPPLWNDVRVEILVTDVNDNAPVMK 795
             + A    SP    +  + + ++DVNDNAPV +
Sbjct: 3386 TVTATDEGSPSFSTNKTLTLKISDVNDNAPVFE 3418



 Score =  360 bits (886), Expect = 3e-97
 Identities = 250/812 (30%), Positives = 396/812 (48%), Gaps = 68/812 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + VLD ND++PVF    Y ASV E A  GT + T+ ATD D G    + Y          
Sbjct: 1251 VTVLDANDNAPVFNQTVYRASVMENAPKGTYITTVNATDADAGSYGRITYNF-------- 1302

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                              +F ID  +G +     +D EK  ++ + V+A DQ       L
Sbjct: 1303 ---------YKQKGAAAQLFNIDSNTGIISVVGEIDHEKDTKFELTVEARDQGG-----L 1348

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            + ++ I +++ID NDN P  +  +++ +V ED     +  IA I   DAD   N  +   
Sbjct: 1349 TDSSKITLDVIDVNDNAPVINAMSFSSTVSED--APPDTTIAIINVKDADTDDNGRVSCF 1406

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            I G    +  S  +L    SLV    LD E++  Y + + A D G P  ++     + + 
Sbjct: 1407 IEGSEDFVVKS--TLRNYYSLVTNVILDREKLSEYNITVVATDSGKPPLTSRKTFNLKVV 1464

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            DVNDNAP F   ++   + EN   G SI+R++A+D DE  NA ++Y + + D    +   
Sbjct: 1465 DVNDNAPVFRERVYNSYLPENNSPGVSILRIRAHDPDENQNARISYILEESD----LGTY 1520

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
            ++++  SG V+     D E     ++ V A DGG PP S+  T              F  
Sbjct: 1521 VSVNAESGVVHAVRSFDYEQIKNIKVTVKAQDGGSPPLSSNVTIDVTVLDVNDNAPVFNQ 1580

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGN----TRGRFSITSQNGRGLIT 424
              Y   + E+ P GT + T+ ATDAD  +  H  ++  +    +RG F+I      GL++
Sbjct: 1581 TVYRASVTENAPKGTYITTVNATDADSGSNGHITLSFSDLKEQSRGIFNI--DENTGLVS 1638

Query: 425  VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
            V   +DF++++R+ + V ATD GG + T+ + I + D N+ APV      ++ V EDAP 
Sbjct: 1639 VLGNIDFEKDKRFEIRVKATDQGGLTSTSKLIIEVVDVNDNAPVITLMSLSSPVSEDAPP 1698

Query: 485  GTTVLV-------------VSATDSDVGINAQITYSL-SSEISNEAVAHHDQQFVINPQT 530
            GTT+ V             V+A D D   N++++Y L  + IS   ++ +     IN + 
Sbjct: 1699 GTTIAVLIENNTPGLSICSVTARDLDWNQNSRVSYYLEDAHISGVPISSY---VSINAEN 1755

Query: 531  GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT--TDVEISVVDVNDNEPVFKQQLYTA 588
            G +   +  D E +  +   V A+DGG P LS     D+ I+V+D NDN PVF Q +Y A
Sbjct: 1756 GVLHAVRSFDYEQVKQFSFIVKAQDGGSPPLSSNKFIDIHITVLDANDNAPVFMQSVYKA 1815

Query: 589  NIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFVIDPASGVIRTNKALDR 647
             + E+A   T VS V ATDAD G+N +I Y + + +D  +  F I+  +G +     +D 
Sbjct: 1816 TVTENAPKDTIVSTVSATDADEGINSKIEYSIANMEDDVQRLFAINRDNGQVSVVGIIDF 1875

Query: 648  ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
            E    ++++  A D G    S    ++I + D ND+ PVF        ++ENSP GT + 
Sbjct: 1876 ERARNYEIRVQASDQGGLTDS---YINIIVLDANDNAPVFSQTVYKTAVTENSPKGTIVT 1932

Query: 708  EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
             + A D D+G N  + YSI+   D      E  +   K  L+ +V  DYE  R  +E+ +
Sbjct: 1933 TVSASDLDQGVNGEITYSIRNTIDKVRDIFEISETDGKVRLIGLV--DYEQAR-NFEIRV 1989

Query: 768  RAASPPLWND---VRVEIL-VTDVNDNAPVMK 795
            +A+    + D   + V+++ ++DVNDNAPV +
Sbjct: 1990 QASDHGGFTDSCKIIVDVIDISDVNDNAPVFE 2021



 Score =  353 bits (869), Expect = 3e-95
 Identities = 262/897 (29%), Positives = 425/897 (47%), Gaps = 66/897 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            ++V+D ND++PV     + ++V E A   TT+  +   D D   N  V   IE       
Sbjct: 1356 LDVIDVNDNAPVINAMSFSSTVSEDAPPDTTIAIINVKDADTDDNGRVSCFIE------- 1408

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
              ED           V+   R      +L+T   LDREK++ Y + V ATD   P    L
Sbjct: 1409 GSED---------FVVKSTLR---NYYSLVTNVILDREKLSEYNITVVATDSGKPP---L 1453

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +S  T ++ ++D NDN P F E+ Y   + E+ S      I +I+A D D   N+ I Y 
Sbjct: 1454 TSRKTFNLKVVDVNDNAPVFRERVYNSYLPENNS--PGVSILRIRAHDPDENQNARISYI 1511

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            +   +     S+++ SG V  V++ DYEQ+++ ++ ++AQDGGSP  S+   + + + DV
Sbjct: 1512 LEESDLGTYVSVNAESGVVHAVRSFDYEQIKNIKVTVKAQDGGSPPLSSNVTIDVTVLDV 1571

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD-KDYTGNVDLPI 309
            NDNAP F  ++++ SV+EN P G  I  V A DAD G N  +T + +D K+ +  +    
Sbjct: 1572 NDNAPVFNQTVYRASVTENAPKGTYITTVNATDADSGSNGHITLSFSDLKEQSRGI---F 1628

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA-----------TATXXXXXXX 358
             ID  +G V   G +D E   ++++ V ATD G    ++            A        
Sbjct: 1629 NIDENTGLVSVLGNIDFEKDKRFEIRVKATDQGGLTSTSKLIIEVVDVNDNAPVITLMSL 1688

Query: 359  XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHY-----EITGGNTRGR 411
                     PG     L E+  PG  + ++TA D D  +++R+ Y      I+G      
Sbjct: 1689 SSPVSEDAPPGTTIAVLIENNTPGLSICSVTARDLDWNQNSRVSYYLEDAHISGVPISSY 1748

Query: 412  FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINIT--DANNYAP 467
             SI ++N  G++   +  D++Q +++   V A D G    S    + I+IT  DAN+ AP
Sbjct: 1749 VSINAEN--GVLHAVRSFDYEQVKQFSFIVKAQDGGSPPLSSNKFIDIHITVLDANDNAP 1806

Query: 468  VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527
            VF  + Y A+V E+AP  T V  VSATD+D GIN++I YS+++ + ++      + F IN
Sbjct: 1807 VFMQSVYKATVTENAPKDTIVSTVSATDADEGINSKIEYSIAN-MEDDV----QRLFAIN 1861

Query: 528  PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT 587
               G ++   ++D E    Y + V A D G   L+D+  + I V+D NDN PVF Q +Y 
Sbjct: 1862 RDNGQVSVVGIIDFERARNYEIRVQASDQG--GLTDSY-INIIVLDANDNAPVFSQTVYK 1918

Query: 588  ANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFVIDPASGVIRTNKALD 646
              + E++  GT V+ V A+D D G+NG I Y + +  D+    F I    G +R    +D
Sbjct: 1919 TAVTENSPKGTIVTTVSASDLDQGVNGEITYSIRNTIDKVRDIFEISETDGKVRLIGLVD 1978

Query: 647  RESVATHDLKAVAIDGGTPPQSSTVIVH-IKIEDINDSPPVFESDCLTFYISENSPIGTT 705
             E     +++  A D G    S  +IV  I I D+ND+ PVFE       +  ++ +G  
Sbjct: 1979 YEQARNFEIRVQASDHGGFTDSCKIIVDVIDISDVNDNAPVFEQSSYQASVQRSADVGYL 2038

Query: 706  IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765
            + ++ A D D G NA + Y +    D   F +  + G  +      +D + ++       
Sbjct: 2039 VTKVVAVDVDSGQNAWLSYKLHKATDRALFEVGAQNGEIRTVRQKPLDREKQNEINLVLT 2098

Query: 766  VIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--V 823
             +    P L   + + I V D NDNAPV           ++         V A DAD  +
Sbjct: 2099 AVDGGDPQLSGSIDIHITVLDANDNAPVFMQSVYKATVTENAPKDTIVSTVSATDADEGI 2158

Query: 824  TDKLQYRILS--GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKA 878
              K++Y I +   N   L  +N+  G + +   ++    +   + V  +D ++  K+
Sbjct: 2159 NSKIEYSIANRQDNVRQLFDINKDNGQVRVVGIIDFEKARNYEISVQASDHLSGSKS 2215



 Score =  350 bits (861), Expect = 3e-94
 Identities = 255/878 (29%), Positives = 424/878 (48%), Gaps = 53/878 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I VLD ND++PVF    Y+ +V E +  GT V T+ A+D D G N E+ Y+I     +T+
Sbjct: 1900 IIVLDANDNAPVFSQTVYKTAVTENSPKGTIVTTVSASDLDQGVNGEITYSIR----NTI 1955

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +              V+D+F I    G +     +D E+   + + V+A+D     +D  
Sbjct: 1956 DK-------------VRDIFEISETDGKVRLIGLVDYEQARNFEIRVQASDHGG-FTDSC 2001

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
                 + ++I D NDN P F + +Y  SV     V    ++ K+ A D D G N+ + Y 
Sbjct: 2002 KIIVDV-IDISDVNDNAPVFEQSSYQASVQRSADV--GYLVTKVVAVDVDSGQNAWLSYK 2058

Query: 191  IIGGNTQMQFSIDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            +     +  F + + +G++  V  K LD E+     LV+ A DGG P  S +  + I + 
Sbjct: 2059 LHKATDRALFEVGAQNGEIRTVRQKPLDREKQNEINLVLTAVDGGDPQLSGSIDIHITVL 2118

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            D NDNAP F  S+++ +V+EN P    +  V A DADEG+N+++ Y++ ++    NV   
Sbjct: 2119 DANDNAPVFMQSVYKATVTENAPKDTIVSTVSATDADEGINSKIEYSIANRQ--DNVRQL 2176

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
              I+  +G V   G +D E    Y++ V A+D     +S   T                 
Sbjct: 2177 FDINKDNGQVRVVGIIDFEKARNYEISVQASDHLSGSKSEPLTEVILEFLDANDNAPVCS 2236

Query: 369  GQ-YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITV 425
               Y+  +AE+ P GT + T++A+DAD+  ++R+ + I+    +        +  G++ +
Sbjct: 2237 QTVYKTSIAENSPKGTVLTTVSASDADQGSNSRITFSISSTADKAADIFEIDSELGVVKL 2296

Query: 426  AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAP 483
               +D++Q    +  + + D G    +  + I+IT  D N+ APVF  + Y A+V E+AP
Sbjct: 2297 TGGIDYEQRHSLLTDIRSVDGGDPQLSGSIDIHITVLDVNDNAPVFMQSVYKATVTENAP 2356

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
              T V  VSATD+D GIN++I YS+++  + ++V+      + +  +  +     +D + 
Sbjct: 2357 KDTIVSTVSATDADEGINSKIEYSIANIDNGQSVS------IQSYYSRELGKGHRVDHKN 2410

Query: 544  MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
                +L   A DGG P LS T  + I+V+D NDN PVF Q++Y A+I E+A+ GT ++ V
Sbjct: 2411 ----ILYKNAIDGGDPQLSGTAQIHITVLDANDNAPVFTQKIYKASITENAVRGTVITTV 2466

Query: 604  GATDADVGLNGRIHYEL-DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
             A+D D G  G+I Y + +  D     F I+  +G +R    +D E    + +   A D 
Sbjct: 2467 SASDLDEGSYGKITYAITNTLDDVPVLFEINETNGEVRVIGTVDYEKARHYQIHVQASDD 2526

Query: 663  G--TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
            G  T      V +HI + D ND+ PVF        I+EN+  GT I  + A D DEG   
Sbjct: 2527 GGLTDSCKIDVDIHITVLDANDNAPVFTHKIYKASITENAVRGTIITTVTASDLDEGSYG 2586

Query: 721  VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL-VIRAASPPLWNDVR 779
             + Y+I     +     E  + + + +    + +  E+P + Y +  +    P L   + 
Sbjct: 2587 KITYAITNSLGNFPMLFEINETNGEIQTREKM-ITLENPMEFYSITAVDGGDPQLSGTIP 2645

Query: 780  VEILVTDVNDNAPVMKDFQIIF-NNYKDCFPVGP-FGRVPAYDAD--VTDKLQYRIL--S 833
            + I V D NDNAP+   F  ++  +  +  P G     V A DAD     K++Y I   +
Sbjct: 2646 IIITVEDANDNAPIC--FMSVYKTSVAENSPKGTVLTTVKASDADQGQNGKVEYHIAKST 2703

Query: 834  GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            G   NL  ++   G + LS  ++    K   ++V   D
Sbjct: 2704 GGTINLFEIDRNAGVLKLSGDIDYEKVKHYQIDVQARD 2741



 Score =  345 bits (847), Expect = 1e-92
 Identities = 261/888 (29%), Positives = 419/888 (47%), Gaps = 72/888 (8%)

Query: 10   QINVLDCNDHSPVFEMQQY---EASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            +I + D ND+ PV     Y   + +V E A  GT +  + A D D G N+ V Y+   + 
Sbjct: 818  RIYITDMNDNPPVVLYPYYTVYKTNVAENAVKGTIITKVSAFDADQGYNSNVTYSFTHIA 877

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
             DT +                 +F+I   +G +    +LD E V +Y + ++A D     
Sbjct: 878  EDTAH-----------------LFQISASTGDITLTGNLDYETVQQYELNLQAKDPWG-- 918

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
               L+  + + ++++D NDN P  S  +++  + ED       V+A I   D D G N  
Sbjct: 919  ---LTGASKLVIDVVDVNDNSPVISMTSFSGKIQEDSPA--GTVVALISVQDLDSGKNGQ 973

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
            +R A+        F+I         + T   LD E+V S+ L + A D GSPS  +   +
Sbjct: 974  VRLAL---EQSSPFTIKPSPRKYYTLVTDAPLDREKVSSFNLTLVATDEGSPSLFSKITI 1030

Query: 244  LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
             +++ D+NDNAP F    ++  V EN   G S++ +QA D D G NA + Y + D D  G
Sbjct: 1031 SLDVTDINDNAPVFSQREYKAYVMENNSPGVSLLTLQASDPDAGQNARIAYYLIDSDVNG 1090

Query: 304  N-VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
            + V    +++  +G ++     D E   ++++ V A DGG PP  + AT           
Sbjct: 1091 SPVSSHFSVNADNGIIHAVRSFDYEQMKEFKIHVRAQDGGSPPLCSNATVVINVQDQNDN 1150

Query: 363  XXXFM-PGQYEVELAEDEPP-----GTPVVTLTATDADEDNR--LHYEITGGNTRGRFSI 414
                + P Q    +  +  P     G  V  + A D D      L Y++     R  F +
Sbjct: 1151 APQVLYPVQSGASVVAEIVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLHKATDRALFEV 1210

Query: 415  TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENA 472
             +QNG  + TV Q      +    L + A D G   RS + ++ + + DAN+ APVF   
Sbjct: 1211 GAQNGE-IRTVRQE---SADDHDSLKLIAVDGGNPQRSGSVIIDVTVLDANDNAPVFNQT 1266

Query: 473  PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
             Y ASV E+AP GT +  V+ATD+D G   +ITY+   +    A     Q F I+  TG 
Sbjct: 1267 VYRASVMENAPKGTYITTVNATDADAGSYGRITYNFYKQKGAAA-----QLFNIDSNTGI 1321

Query: 533  ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592
            I+    +D E  + + LTV ARD G   L+D++ + + V+DVNDN PV     +++ + E
Sbjct: 1322 ISVVGEIDHEKDTKFELTVEARDQG--GLTDSSKITLDVIDVNDNAPVINAMSFSSTVSE 1379

Query: 593  DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652
            DA   T+++ +   DAD   NGR+   ++  +       +     ++ TN  LDRE ++ 
Sbjct: 1380 DAPPDTTIAIINVKDADTDDNGRVSCFIEGSEDFVVKSTLRNYYSLV-TNVILDREKLSE 1438

Query: 653  HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
            +++  VA D G PP +S    ++K+ D+ND+ PVF       Y+ EN+  G +I  IRAH
Sbjct: 1439 YNITVVATDSGKPPLTSRKTFNLKVVDVNDNAPVFRERVYNSYLPENNSPGVSILRIRAH 1498

Query: 713  DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA--- 769
            DPDE  NA + Y ++  D     S+    G   A    +   DYE   K  ++ ++A   
Sbjct: 1499 DPDENQNARISYILEESDLGTYVSVNAESGVVHA----VRSFDYEQ-IKNIKVTVKAQDG 1553

Query: 770  ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVGPF-GRVPAYDADVTDK- 826
             SPPL ++V +++ V DVNDNAPV    Q ++  +  +  P G +   V A DAD     
Sbjct: 1554 GSPPLSSNVTIDVTVLDVNDNAPVFN--QTVYRASVTENAPKGTYITTVNATDADSGSNG 1611

Query: 827  ---LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
               L +  L   +  +  ++E TG +++   ++    K   + V  TD
Sbjct: 1612 HITLSFSDLKEQSRGIFNIDENTGLVSVLGNIDFEKDKRFEIRVKATD 1659



 Score =  310 bits (762), Expect = 3e-82
 Identities = 232/756 (30%), Positives = 368/756 (48%), Gaps = 46/756 (6%)

Query: 89   VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
            +  +D  +G +  R  LDREK   Y + + A D  +P    L S+ T+ + + D NDN P
Sbjct: 671  ILEVDSVTGEV--RIMLDREKCTHYNITITAVDAGTPP---LFSSKTVAITVTDINDNPP 725

Query: 149  QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
             F    YTV   E+      PVI KIKA DAD G N+ I Y++   ++ +  SI++ +G+
Sbjct: 726  IFRHANYTVQFAEN-QPRGTPVI-KIKADDADGGQNARILYSL-SEDSAIYLSINTETGE 782

Query: 209  VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF---YTSLFQES 265
            +  ++  DYE    +     A+DGG PS ++T  + I I D+NDN P     Y ++++ +
Sbjct: 783  IFTIRPFDYEASTHFYAQAMARDGGRPSFTSTCTIRIYITDMNDNPPVVLYPYYTVYKTN 842

Query: 266  VSENVPIGYSIVRVQAYDADEGVNAELTYTMTD-KDYTGNVDLPITIDPRSGWVYTSGQL 324
            V+EN   G  I +V A+DAD+G N+ +TY+ T   + T ++     I   +G +  +G L
Sbjct: 843  VAENAVKGTIITKVSAFDADQGYNSNVTYSFTHIAEDTAHL---FQISASTGDITLTGNL 899

Query: 325  DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
            D ET  +Y+L + A D      ++                      +  ++ ED P GT 
Sbjct: 900  DYETVQQYELNLQAKDPWGLTGASKLVIDVVDVNDNSPVISMT--SFSGKIQEDSPAGTV 957

Query: 385  VVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ-PLDFKQERRYVLTVSA 443
            V  ++  D D        +    +   F+I     +    V   PLD ++   + LT+ A
Sbjct: 958  VALISVQDLDSGKNGQVRLALEQS-SPFTIKPSPRKYYTLVTDAPLDREKVSSFNLTLVA 1016

Query: 444  TDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501
            TD G  S      + +++TD N+ APVF    Y A V E+   G ++L + A+D D G N
Sbjct: 1017 TDEGSPSLFSKITISLDVTDINDNAPVFSQREYKAYVMENNSPGVSLLTLQASDPDAGQN 1076

Query: 502  AQITYSL-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560
            A+I Y L  S+++   V+ H   F +N   G I   +  D E M  + + V A+DGG P 
Sbjct: 1077 ARIAYYLIDSDVNGSPVSSH---FSVNADNGIIHAVRSFDYEQMKEFKIHVRAQDGGSPP 1133

Query: 561  LSDTTDVEISVVDVNDNEP--VFKQQLYTANIME----DALVGTSVSQVGATDADVGLNG 614
            L     V I+V D NDN P  ++  Q   + + E     A VG  V++V A D D G N 
Sbjct: 1134 LCSNATVVINVQDQNDNAPQVLYPVQSGASVVAEIVPRSADVGYLVTKVVAVDVDSGQNA 1193

Query: 615  RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD-LKAVAIDGGTPPQSSTVIV 673
             + Y+L  K  +   F +   +G IRT +   +ES   HD LK +A+DGG P +S +VI+
Sbjct: 1194 WLSYKLH-KATDRALFEVGAQNGEIRTVR---QESADDHDSLKLIAVDGGNPQRSGSVII 1249

Query: 674  HIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI--KGGDD 731
             + + D ND+ PVF        + EN+P GT I  + A D D G    + Y+   + G  
Sbjct: 1250 DVTVLDANDNAPVFNQTVYRASVMENAPKGTYITTVNATDADAGSYGRITYNFYKQKGAA 1309

Query: 732  SNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRAASPP-LWNDVRVEILVTDVND 789
            +  F++++  G     ++++V ++D+E   K +EL + A     L +  ++ + V DVND
Sbjct: 1310 AQLFNIDSNTG-----IISVVGEIDHEKDTK-FELTVEARDQGGLTDSSKITLDVIDVND 1363

Query: 790  NAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD 825
            NAPV+          +D  P      +   DAD  D
Sbjct: 1364 NAPVINAMSFSSTVSEDAPPDTTIAIINVKDADTDD 1399



 Score =  310 bits (761), Expect = 4e-82
 Identities = 258/891 (28%), Positives = 398/891 (44%), Gaps = 81/891 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND+ P+F    Y     E    GT V+ +KA D D G+NA + Y++        
Sbjct: 715  ITVTDINDNPPIFRHANYTVQFAENQPRGTPVIKIKADDADGGQNARILYSLS------- 767

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
              ED+                I+  +G + T    D E    +     A D   P     
Sbjct: 768  --EDSAI-----------YLSINTETGEIFTIRPFDYEASTHFYAQAMARDGGRP---SF 811

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTV-SVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            +ST TI + I D NDN P      YTV   +   +     +I K+ A DAD G NS + Y
Sbjct: 812  TSTCTIRIYITDMNDNPPVVLYPYYTVYKTNVAENAVKGTIITKVSAFDADQGYNSNVTY 871

Query: 190  AI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            +   I  +T   F I + +GD++L   LDYE V+ Y L ++A+D      +  ++L+I++
Sbjct: 872  SFTHIAEDTAHLFQISASTGDITLTGNLDYETVQQYELNLQAKDPW--GLTGASKLVIDV 929

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
             DVNDN+P    + F   + E+ P G  +  +   D D G N ++   +           
Sbjct: 930  VDVNDNSPVISMTSFSGKIQEDSPAGTVVALISVQDLDSGKNGQVRLALEQSS------- 982

Query: 308  PITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
            P TI P     Y   T   LDRE  + + L + ATD G P   +  T             
Sbjct: 983  PFTIKPSPRKYYTLVTDAPLDREKVSSFNLTLVATDEGSPSLFSKITISLDVTDINDNAP 1042

Query: 365  XFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHY-----EITGGNTRGRFSITSQ 417
             F   +Y+  + E+  PG  ++TL A+D D  ++ R+ Y     ++ G      FS+ + 
Sbjct: 1043 VFSQREYKAYVMENNSPGVSLLTLQASDPDAGQNARIAYYLIDSDVNGSPVSSHFSVNAD 1102

Query: 418  NGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYA-----PVFE 470
            N  G+I   +  D++Q + + + V A D G       A V IN+ D N+ A     PV  
Sbjct: 1103 N--GIIHAVRSFDYEQMKEFKIHVRAQDGGSPPLCSNATVVINVQDQNDNAPQVLYPVQS 1160

Query: 471  NAPYTASVF-EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
             A   A +    A +G  V  V A D D G NA ++Y L  + ++ A+      F +  Q
Sbjct: 1161 GASVVAEIVPRSADVGYLVTKVVAVDVDSGQNAWLSYKL-HKATDRAL------FEVGAQ 1213

Query: 530  TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589
             G I T +    +      L + A DGG P  S +  ++++V+D NDN PVF Q +Y A+
Sbjct: 1214 NGEIRTVRQESADDHDS--LKLIAVDGGNPQRSGSVIIDVTVLDANDNAPVFNQTVYRAS 1271

Query: 590  IMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFVIDPASGVIRTNKALDRE 648
            +ME+A  GT ++ V ATDAD G  GRI Y     K      F ID  +G+I     +D E
Sbjct: 1272 VMENAPKGTYITTVNATDADAGSYGRITYNFYKQKGAAAQLFNIDSNTGIISVVGEIDHE 1331

Query: 649  SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
                 +L   A D G    SS +   + + D+ND+ PV  +   +  +SE++P  TTI  
Sbjct: 1332 KDTKFELTVEARDQGGLTDSSKIT--LDVIDVNDNAPVINAMSFSSTVSEDAPPDTTIAI 1389

Query: 709  IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768
            I   D D   N  V   I+G +D   F +++    +   LVT V LD E    +Y + + 
Sbjct: 1390 INVKDADTDDNGRVSCFIEGSED---FVVKSTL-RNYYSLVTNVILDREK-LSEYNITVV 1444

Query: 769  A---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY--KDCFPVGPFGRVPAYDADV 823
            A     PPL +     + V DVNDNAPV +  + ++N+Y  ++  P     R+ A+D D 
Sbjct: 1445 ATDSGKPPLTSRKTFNLKVVDVNDNAPVFR--ERVYNSYLPENNSPGVSILRIRAHDPDE 1502

Query: 824  TD--KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
                ++ Y +   +    + +N  +G +      +    K   + V   DG
Sbjct: 1503 NQNARISYILEESDLGTYVSVNAESGVVHAVRSFDYEQIKNIKVTVKAQDG 1553



 Score =  299 bits (734), Expect = 7e-79
 Identities = 192/590 (32%), Positives = 301/590 (51%), Gaps = 26/590 (4%)

Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS 164
           LDRE+    T+++ A D  +P     S T  IHV ++D NDN P FS+  Y VS+ E+  
Sbjct: 1   LDREQQKEVTLILTAVDGGTPPR---SGTVAIHVTVLDANDNAPVFSQAVYKVSLPENSP 57

Query: 165 VTDNPVIAKIKATDADVGANSAIRYAI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222
           V  + V+  + ATDAD G N  + Y    +    +  FS++  +G++++   +DYE+  +
Sbjct: 58  V--DTVVVTVSATDADEGQNGKVTYVFGHVSEEDKTLFSLNRNTGEITVTGAIDYEEKSA 115

Query: 223 YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY 282
           Y L + A+D      ++ + ++I++ D NDNAP   +      + E+   G  +  +   
Sbjct: 116 YELRVLAKDAAG--LTSYSMVIIDVTDTNDNAPVIISKSLNIPIPESALPGTEVGIINVQ 173

Query: 283 DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDG 341
           D D   N ++  ++       NV   +    ++ + + T+G+LDRE  ++Y + +TATD 
Sbjct: 174 DRDSENNGQVRCSIQQ-----NVPFKLVPSIKNYYSLVTTGELDRELLSEYNITITATDE 228

Query: 342 GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRL 399
           G PP S+T                F    Y+V L E+ P  T VVT++ATDADE  +  +
Sbjct: 229 GSPPLSSTKNIHLTVADVNDNPPVFQQAVYKVSLPENSPVDTVVVTVSATDADEGQNGEV 288

Query: 400 HYEITGGNTRGRFSITS-QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN 458
            YE  G  +    +I S     G IT+   LD++ E  + L + ATD  G    + V I+
Sbjct: 289 TYEF-GHISENDITIFSLDQNSGKITLIGSLDYEDEASFDLPIQATDGLGLVSYSTVVID 347

Query: 459 ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL-SSEISNEAV 517
           ++D N+  PVF+   Y A V E+   G+++  VSATD D   N  + YSL SS+++   V
Sbjct: 348 VSDVNDNPPVFQQQNYRAHVQENNKAGSSISSVSATDPDWRQNGTVVYSLLSSDVNGAPV 407

Query: 518 AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577
           +       IN  TG I   +  D E M  + + V ARD G P LS    + ++V+D NDN
Sbjct: 408 SSF---LSINGDTGVIHAVRSFDYEQMKSFKVLVLARDNGSPPLSSNVSIHVTVLDANDN 464

Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP-KDREEGSFVIDPAS 636
            PVF Q +Y  ++ E++ V T V  V ATDAD G NG + YE     +  +  F +D  +
Sbjct: 465 APVFSQAVYKVSLPENSPVDTVVVTVSATDADEGQNGEVTYEFGHIMEDYKHLFNLDRKT 524

Query: 637 GVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686
           GVI     +D E  AT  L+ +A DG      S V+  I + D+ND+ P+
Sbjct: 525 GVISIKGPVDFEEEATFSLRIIAKDGSGLTSYSNVL--ISVSDVNDNSPI 572



 Score =  284 bits (697), Expect = 2e-74
 Identities = 218/790 (27%), Positives = 368/790 (46%), Gaps = 75/790 (9%)

Query: 96   SGALLT-RASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKT 154
            SG L+T R  LDRE  A + + +   D   P     S TA+IH++++D NDN P  S   
Sbjct: 586  SGRLITSRKPLDRESKADHFLTLSGVDGGRPSR---SGTASIHIHVLDANDNIPVGS--- 639

Query: 155  YTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI--IGGNTQMQFSIDSLSGDVSLV 212
                           V+ K+ ATD D G   A+ Y+   +   T+    +DS++G+V ++
Sbjct: 640  ---------------VLVKLNATDLDSGIYGAVSYSFSHVPDKTRGILEVDSVTGEVRIM 684

Query: 213  KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI 272
              LD E+   Y + I A D G+P   ++  + I + D+NDN P F  + +    +EN P 
Sbjct: 685  --LDREKCTHYNITITAVDAGTPPLFSSKTVAITVTDINDNPPIFRHANYTVQFAENQPR 742

Query: 273  GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332
            G  +++++A DAD G NA + Y++++        + ++I+  +G ++T    D E    +
Sbjct: 743  GTPVIKIKADDADGGQNARILYSLSEDSA-----IYLSINTETGEIFTIRPFDYEASTHF 797

Query: 333  QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV---ELAEDEPPGTPVVTLT 389
                 A DGG P  ++T T               +   Y V    +AE+   GT +  ++
Sbjct: 798  YAQAMARDGGRPSFTSTCTIRIYITDMNDNPPVVLYPYYTVYKTNVAENAVKGTIITKVS 857

Query: 390  ATDADE--DNRLHYEIT--GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445
            A DAD+  ++ + Y  T    +T   F I++  G   IT+   LD++  ++Y L + A D
Sbjct: 858  AFDADQGYNSNVTYSFTHIAEDTAHLFQISASTGD--ITLTGNLDYETVQQYELNLQAKD 915

Query: 446  SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505
              G +  + + I++ D N+ +PV     ++  + ED+P GT V ++S  D D G N Q+ 
Sbjct: 916  PWGLTGASKLVIDVVDVNDNSPVISMTSFSGKIQEDSPAGTVVALISVQDLDSGKNGQVR 975

Query: 506  YSLSSEISNEAVAHHDQQFVINPQTG---AITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
             +L               F I P       + T+  LDRE +S + LT+ A D G PSL 
Sbjct: 976  LALEQS----------SPFTIKPSPRKYYTLVTDAPLDREKVSSFNLTLVATDEGSPSLF 1025

Query: 563  DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP 622
                + + V D+NDN PVF Q+ Y A +ME+   G S+  + A+D D G N RI Y L  
Sbjct: 1026 SKITISLDVTDINDNAPVFSQREYKAYVMENNSPGVSLLTLQASDPDAGQNARIAYYLID 1085

Query: 623  KDRE----EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678
             D         F ++  +G+I   ++ D E +    +   A DGG+PP  S   V I ++
Sbjct: 1086 SDVNGSPVSSHFSVNADNGIIHAVRSFDYEQMKEFKIHVRAQDGGSPPLCSNATVVINVQ 1145

Query: 679  DINDSPPVF------ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732
            D ND+ P         +  +   +  ++ +G  + ++ A D D G NA + Y +    D 
Sbjct: 1146 DQNDNAPQVLYPVQSGASVVAEIVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLHKATDR 1205

Query: 733  NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP 792
              F +  + G  +       D D++S +    + +   +P     V +++ V D NDNAP
Sbjct: 1206 ALFEVGAQNGEIRTVRQESAD-DHDSLKL---IAVDGGNPQRSGSVIIDVTVLDANDNAP 1261

Query: 793  VMKDFQIIFN-NYKDCFPVGPF-GRVPAYDADVTD--KLQYRIL--SGNNANLILLNETT 846
            V    Q ++  +  +  P G +   V A DAD     ++ Y      G  A L  ++  T
Sbjct: 1262 VFN--QTVYRASVMENAPKGTYITTVNATDADAGSYGRITYNFYKQKGAAAQLFNIDSNT 1319

Query: 847  GSMTLSPQLN 856
            G +++  +++
Sbjct: 1320 GIISVVGEID 1329



 Score =  273 bits (670), Expect = 4e-71
 Identities = 186/591 (31%), Positives = 291/591 (49%), Gaps = 29/591 (4%)

Query: 215 LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY 274
           LD EQ +   L++ A DGG+P RS T  + + + D NDNAP F  ++++ S+ EN P+  
Sbjct: 1   LDREQQKEVTLILTAVDGGTPPRSGTVAIHVTVLDANDNAPVFSQAVYKVSLPENSPVDT 60

Query: 275 SIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI-TIDPRSGWVYTSGQLDRETQAKYQ 333
            +V V A DADEG N ++TY      +    D  + +++  +G +  +G +D E ++ Y+
Sbjct: 61  VVVTVSATDADEGQNGKVTYVF---GHVSEEDKTLFSLNRNTGEITVTGAIDYEEKSAYE 117

Query: 334 LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393
           L V A D      ++ +                +     + + E   PGT V  +   D 
Sbjct: 118 LRVLAKDAAG--LTSYSMVIIDVTDTNDNAPVIISKSLNIPIPESALPGTEVGIINVQDR 175

Query: 394 DEDNRLHYEIT-GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--S 450
           D +N      +   N   +   + +N   L+T  + LD +    Y +T++ATD G    S
Sbjct: 176 DSENNGQVRCSIQQNVPFKLVPSIKNYYSLVTTGE-LDRELLSEYNITITATDEGSPPLS 234

Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510
            T  + + + D N+  PVF+ A Y  S+ E++P+ T V+ VSATD+D G N ++TY    
Sbjct: 235 STKNIHLTVADVNDNPPVFQQAVYKVSLPENSPVDTVVVTVSATDADEGQNGEVTYEFGH 294

Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG-GVPSLSDTTDVEI 569
              N+        F ++  +G IT    LD E  + + L + A DG G+ S S    V I
Sbjct: 295 ISENDITI-----FSLDQNSGKITLIGSLDYEDEASFDLPIQATDGLGLVSYST---VVI 346

Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL---DPKDRE 626
            V DVNDN PVF+QQ Y A++ E+   G+S+S V ATD D   NG + Y L   D     
Sbjct: 347 DVSDVNDNPPVFQQQNYRAHVQENNKAGSSISSVSATDPDWRQNGTVVYSLLSSDVNGAP 406

Query: 627 EGSFV-IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685
             SF+ I+  +GVI   ++ D E + +  +  +A D G+PP SS V +H+ + D ND+ P
Sbjct: 407 VSSFLSINGDTGVIHAVRSFDYEQMKSFKVLVLARDNGSPPLSSNVSIHVTVLDANDNAP 466

Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG--GDDSNSFSLETRQGS 743
           VF        + ENSP+ T +  + A D DEG N  V Y       D  + F+L+ + G 
Sbjct: 467 VFSQAVYKVSLPENSPVDTVVVTVSATDADEGQNGEVTYEFGHIMEDYKHLFNLDRKTG- 525

Query: 744 DKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVM 794
               +     +D+E        +I      L +   V I V+DVNDN+P++
Sbjct: 526 ---VISIKGPVDFEEEATFSLRIIAKDGSGLTSYSNVLISVSDVNDNSPII 573



 Score =  242 bits (593), Expect = 8e-62
 Identities = 177/580 (30%), Positives = 287/580 (49%), Gaps = 48/580 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + VLD ND++PVF    Y+ S+ E +   T V+T+ ATD D G+N +V Y    V     
Sbjct: 31  VTVLDANDNAPVFSQAVYKVSLPENSPVDTVVVTVSATDADEGQNGKVTYVFGHV----- 85

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           + ED            + +F ++  +G +    ++D E+ + Y + V A D A      L
Sbjct: 86  SEED------------KTLFSLNRNTGEITVTGAIDYEEKSAYELRVLAKDAAG-----L 128

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           +S + + +++ D NDN P    K+  + + E  S      +  I   D D   N  +R +
Sbjct: 129 TSYSMVIIDVTDTNDNAPVIISKSLNIPIPE--SALPGTEVGIINVQDRDSENNGQVRCS 186

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            I  N   +  + S+    SLV T  LD E +  Y + I A D GSP  S+T  + + + 
Sbjct: 187 -IQQNVPFKL-VPSIKNYYSLVTTGELDRELLSEYNITITATDEGSPPLSSTKNIHLTVA 244

Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
           DVNDN P F  ++++ S+ EN P+   +V V A DADEG N E+TY   +  +    D+ 
Sbjct: 245 DVNDNPPVFQQAVYKVSLPENSPVDTVVVTVSATDADEGQNGEVTY---EFGHISENDIT 301

Query: 309 I-TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
           I ++D  SG +   G LD E +A + L + ATDG      + +T              F 
Sbjct: 302 IFSLDQNSGKITLIGSLDYEDEASFDLPIQATDG--LGLVSYSTVVIDVSDVNDNPPVFQ 359

Query: 368 PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGR--FSITSQNG-RGL 422
              Y   + E+   G+ + +++ATD D  ++  + Y +   +  G    S  S NG  G+
Sbjct: 360 QQNYRAHVQENNKAGSSISSVSATDPDWRQNGTVVYSLLSSDVNGAPVSSFLSINGDTGV 419

Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFE 480
           I   +  D++Q + + + V A D+G    ++ V I++T  DAN+ APVF  A Y  S+ E
Sbjct: 420 IHAVRSFDYEQMKSFKVLVLARDNGSPPLSSNVSIHVTVLDANDNAPVFSQAVYKVSLPE 479

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           ++P+ T V+ VSATD+D G N ++TY          +  +   F ++ +TG I+    +D
Sbjct: 480 NSPVDTVVVTVSATDADEGQNGEVTYEF-----GHIMEDYKHLFNLDRKTGVISIKGPVD 534

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580
            E  + + L + A+DG    L+  ++V ISV DVNDN P+
Sbjct: 535 FEEEATFSLRIIAKDGS--GLTSYSNVLISVSDVNDNSPI 572



 Score =  194 bits (472), Expect = 4e-47
 Identities = 132/372 (35%), Positives = 190/372 (51%), Gaps = 18/372 (4%)

Query: 429 LDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
           LD +Q++   L ++A D G   RS T  + + + DAN+ APVF  A Y  S+ E++P+ T
Sbjct: 1   LDREQQKEVTLILTAVDGGTPPRSGTVAIHVTVLDANDNAPVFSQAVYKVSLPENSPVDT 60

Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
            V+ VSATD+D G N ++TY +   +S E        F +N  TG IT    +D E  S 
Sbjct: 61  VVVTVSATDADEGQNGKVTY-VFGHVSEE----DKTLFSLNRNTGEITVTGAIDYEEKSA 115

Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
           Y L V A+D     L+  + V I V D NDN PV   +     I E AL GT V  +   
Sbjct: 116 YELRVLAKDAA--GLTSYSMVIIDVTDTNDNAPVIISKSLNIPIPESALPGTEVGIINVQ 173

Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
           D D   NG++   +      +    I     ++ T + LDRE ++ +++   A D G+PP
Sbjct: 174 DRDSENNGQVRCSIQQNVPFKLVPSIKNYYSLVTTGE-LDRELLSEYNITITATDEGSPP 232

Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
            SST  +H+ + D+ND+PPVF+       + ENSP+ T +  + A D DEG N  V Y  
Sbjct: 233 LSSTKNIHLTVADVNDNPPVFQQAVYKVSLPENSPVDTVVVTVSATDADEGQNGEVTYEF 292

Query: 727 K--GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP-PLWNDVRVEIL 783
                +D   FSL+  Q S K  L+    LDYE     ++L I+A     L +   V I 
Sbjct: 293 GHISENDITIFSLD--QNSGKITLIG--SLDYED-EASFDLPIQATDGLGLVSYSTVVID 347

Query: 784 VTDVNDNAPVMK 795
           V+DVNDN PV +
Sbjct: 348 VSDVNDNPPVFQ 359



 Score =  175 bits (427), Expect = 1e-41
 Identities = 137/417 (32%), Positives = 216/417 (51%), Gaps = 44/417 (10%)

Query: 386 VTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445
           V ++ +D ++++ +   +T   T G F     +GR LIT  +PLD + +  + LT+S  D
Sbjct: 559 VLISVSDVNDNSPIIIPLT--ETPGSFM---PSGR-LITSRKPLDRESKADHFLTLSGVD 612

Query: 446 SG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503
            G   RS TA + I++ DAN                ++ P+G+ ++ ++ATD D GI   
Sbjct: 613 GGRPSRSGTASIHIHVLDAN----------------DNIPVGSVLVKLNATDLDSGIYGA 656

Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD 563
           ++YS  S + ++     +    ++  TG +    +LDRE  + Y +T+TA D G P L  
Sbjct: 657 VSYSF-SHVPDKTRGILE----VDSVTGEVRI--MLDREKCTHYNITITAVDAGTPPLFS 709

Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK 623
           +  V I+V D+NDN P+F+   YT    E+   GT V ++ A DAD G N RI Y L   
Sbjct: 710 SKTVAITVTDINDNPPIFRHANYTVQFAENQPRGTPVIKIKADDADGGQNARILYSLSED 769

Query: 624 DREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS 683
                S  I+  +G I T +  D E+      +A+A DGG P  +ST  + I I D+ND+
Sbjct: 770 SAIYLS--INTETGEIFTIRPFDYEASTHFYAQAMARDGGRPSFTSTCTIRIYITDMNDN 827

Query: 684 PPVFESDCLTFY---ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK--GGDDSNSFSLE 738
           PPV      T Y   ++EN+  GT I ++ A D D+G N+ V YS      D ++ F + 
Sbjct: 828 PPVVLYPYYTVYKTNVAENAVKGTIITKVSAFDADQGYNSNVTYSFTHIAEDTAHLFQIS 887

Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRAASP-PLWNDVRVEILVTDVNDNAPVM 794
              G    ++    +LDYE+  ++YEL ++A  P  L    ++ I V DVNDN+PV+
Sbjct: 888 ASTG----DITLTGNLDYETV-QQYELNLQAKDPWGLTGASKLVIDVVDVNDNSPVI 939



 Score =  151 bits (365), Expect = 4e-34
 Identities = 107/339 (31%), Positives = 166/339 (48%), Gaps = 33/339 (9%)

Query: 528 PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT 587
           P    IT+ K LDRE+ + + LT++  DGG PS S T  + I V+D NDN P        
Sbjct: 585 PSGRLITSRKPLDRESKADHFLTLSGVDGGRPSRSGTASIHIHVLDANDNIP-------- 636

Query: 588 ANIMEDALVGTSVSQVGATDADVGLNGRIHYELD-PKDREEGSFVIDPASGVIRTNKALD 646
                   VG+ + ++ ATD D G+ G + Y      D+  G   +D  +G +R    LD
Sbjct: 637 --------VGSVLVKLNATDLDSGIYGAVSYSFSHVPDKTRGILEVDSVTGEVRI--MLD 686

Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706
           RE    +++   A+D GTPP  S+  V I + DIND+PP+F     T   +EN P GT +
Sbjct: 687 REKCTHYNITITAVDAGTPPLFSSKTVAITVTDINDNPPIFRHANYTVQFAENQPRGTPV 746

Query: 707 GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV 766
            +I+A D D G NA + YS+   D +   S+ T  G    E+ T+   DYE+    Y   
Sbjct: 747 IKIKADDADGGQNARILYSL-SEDSAIYLSINTETG----EIFTIRPFDYEASTHFYAQA 801

Query: 767 IR--AASPPLWNDVRVEILVTDVNDNAPVM--KDFQIIFNNYKDCFPVGP-FGRVPAYDA 821
           +      P   +   + I +TD+NDN PV+    + +   N  +    G    +V A+DA
Sbjct: 802 MARDGGRPSFTSTCTIRIYITDMNDNPPVVLYPYYTVYKTNVAENAVKGTIITKVSAFDA 861

Query: 822 D--VTDKLQYRI--LSGNNANLILLNETTGSMTLSPQLN 856
           D      + Y    ++ + A+L  ++ +TG +TL+  L+
Sbjct: 862 DQGYNSNVTYSFTHIAEDTAHLFQISASTGDITLTGNLD 900



 Score =  142 bits (345), Expect = 9e-32
 Identities = 112/345 (32%), Positives = 167/345 (48%), Gaps = 19/345 (5%)

Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
           LDRE      L +TA DGG P  S T  + ++V+D NDN PVF Q +Y  ++ E++ V T
Sbjct: 1   LDREQQKEVTLILTAVDGGTPPRSGTVAIHVTVLDANDNAPVFSQAVYKVSLPENSPVDT 60

Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKALDRESVATHDLKA 657
            V  V ATDAD G NG++ Y       E+ + F ++  +G I    A+D E  + ++L+ 
Sbjct: 61  VVVTVSATDADEGQNGKVTYVFGHVSEEDKTLFSLNRNTGEITVTGAIDYEEKSAYELRV 120

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
           +A D       S VI  I + D ND+ PV  S  L   I E++  GT +G I   D D  
Sbjct: 121 LAKDAAGLTSYSMVI--IDVTDTNDNAPVIISKSLNIPIPESALPGTEVGIINVQDRDSE 178

Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPL 774
            N  V  SI+    +  F L      +   LVT  +LD E    +Y + I A    SPPL
Sbjct: 179 NNGQVRCSIQ---QNVPFKL-VPSIKNYYSLVTTGELDREL-LSEYNITITATDEGSPPL 233

Query: 775 WNDVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVGP-FGRVPAYDAD--VTDKLQYR 830
            +   + + V DVNDN PV +  Q ++  +  +  PV      V A DAD     ++ Y 
Sbjct: 234 SSTKNIHLTVADVNDNPPVFQ--QAVYKVSLPENSPVDTVVVTVSATDADEGQNGEVTYE 291

Query: 831 I--LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGV 873
              +S N+  +  L++ +G +TL   L+        + +  TDG+
Sbjct: 292 FGHISENDITIFSLDQNSGKITLIGSLDYEDEASFDLPIQATDGL 336



 Score =  137 bits (331), Expect = 5e-30
 Identities = 86/263 (32%), Positives = 133/263 (50%), Gaps = 30/263 (11%)

Query: 2    SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
            S P   +  + VLD ND++P F    Y+AS+ E  S G++VL + A D D G N EV Y+
Sbjct: 3286 SPPLSSNINVIVLDANDNAPAFSQSVYKASIPENFSKGSSVLKVSAADGDTGSNGEVTYS 3345

Query: 62   IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS---LDREKVARYTVLVK 118
            +                          +F ID  +G +    +   LDRE ++ Y + V 
Sbjct: 3346 LS-----------------QSSESFSGLFNIDSNTGDITVNVTDDLLDREMLSEYNITVT 3388

Query: 119  ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178
            ATD+ SP     S+  T+ + I D NDN P F  ++YT  + E+ S      +  +KA D
Sbjct: 3389 ATDEGSP---SFSTNKTLTLKISDVNDNAPVFERQSYTAFIMENNS--PGVSVLSVKAHD 3443

Query: 179  ADVGANSAIRY----AIIGGNTQMQF-SIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233
             D G N+ I Y     ++ G +   F S+ + SG++   ++ DYEQ + + + ++AQDGG
Sbjct: 3444 RDSGNNARISYFLEDVVVNGVSASTFISVHAESGEILAARSFDYEQTKDFSIRVKAQDGG 3503

Query: 234  SPSRSNTTQLLINIRDVNDNAPR 256
            SP  S+   + I I+D NDNAP+
Sbjct: 3504 SPPLSSNVSVKILIQDQNDNAPQ 3526



 Score =  132 bits (318), Expect = 2e-28
 Identities = 96/291 (32%), Positives = 150/291 (51%), Gaps = 27/291 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I+V D ND+ PVF+ Q Y A V+E   +G+++ ++ ATD D  +N  V Y+  L+++D  
Sbjct: 346 IDVSDVNDNPPVFQQQNYRAHVQENNKAGSSISSVSATDPDWRQNGTVVYS--LLSSDV- 402

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                          V     I+G +G +    S D E++  + VLV A D  SP    L
Sbjct: 403 -----------NGAPVSSFLSINGDTGVIHAVRSFDYEQMKSFKVLVLARDNGSP---PL 448

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           SS  +IHV ++D NDN P FS+  Y VS+ E+  V  + V+  + ATDAD G N  + Y 
Sbjct: 449 SSNVSIHVTVLDANDNAPVFSQAVYKVSLPENSPV--DTVVVTVSATDADEGQNGEVTYE 506

Query: 191 I--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG-GSPSRSNTTQLLINI 247
              I  + +  F++D  +G +S+   +D+E+  ++ L I A+DG G  S SN   +LI++
Sbjct: 507 FGHIMEDYKHLFNLDRKTGVISIKGPVDFEEEATFSLRIIAKDGSGLTSYSN---VLISV 563

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
            DVNDN+P        E+    +P G  I   +  D +   +  LT +  D
Sbjct: 564 SDVNDNSPIIIP--LTETPGSFMPSGRLITSRKPLDRESKADHFLTLSGVD 612



 Score = 86.6 bits (205), Expect = 9e-15
 Identities = 82/268 (30%), Positives = 122/268 (45%), Gaps = 29/268 (10%)

Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES 649
           I +D    TS S V  + +DV  N  I   + P     GSF+  P+  +I + K LDRES
Sbjct: 546 IAKDGSGLTSYSNVLISVSDVNDNSPI---IIPLTETPGSFM--PSGRLITSRKPLDRES 600

Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
            A H L    +DGG P +S T  +HI + D ND                N P+G+ + ++
Sbjct: 601 KADHFLTLSGVDGGRPSRSGTASIHIHVLDAND----------------NIPVGSVLVKL 644

Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
            A D D G    V YS     D     LE    S   E+  M+D +  +        + A
Sbjct: 645 NATDLDSGIYGAVSYSFSHVPDKTRGILEV--DSVTGEVRIMLDREKCTHYNITITAVDA 702

Query: 770 ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDK 826
            +PPL++   V I VTD+NDN P+ +        + +  P G P  ++ A DAD     +
Sbjct: 703 GTPPLFSSKTVAITVTDINDNPPIFRHANYTV-QFAENQPRGTPVIKIKADDADGGQNAR 761

Query: 827 LQYRILSGNNANLILLNETTGSM-TLSP 853
           + Y  LS ++A  + +N  TG + T+ P
Sbjct: 762 ILYS-LSEDSAIYLSINTETGEIFTIRP 788


>UniRef50_UPI00006A0F38 Cluster: dachsous 2 isoform 1; n=1; Xenopus
            tropicalis|Rep: dachsous 2 isoform 1 - Xenopus tropicalis
          Length = 3555

 Score =  378 bits (931), Expect = e-103
 Identities = 269/870 (30%), Positives = 421/870 (48%), Gaps = 76/870 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I V D ND+ P+F  + Y  S+ E     +TVL + A D+D G N+++ Y+    +   
Sbjct: 2679 RITVTDMNDNFPIFGQEVYTVSINENIPLNSTVLCVSANDKDQGINSQITYSFSATSKQA 2738

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                                F I+  +G + T+ +LD EK   Y + V+A  Q       
Sbjct: 2739 SRS-----------------FSINSETGEIKTKENLDFEKTKNYEISVQAKIQ----KHH 2777

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            + S   I + + D NDN+P F+++ Y V++ E+I +  +  + ++ A+D D G N+ I Y
Sbjct: 2778 ILSLINIQITVTDFNDNFPVFTQEVYKVNIHENIPI--HSTVLQVNASDKDEGINAQITY 2835

Query: 190  AI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            +      N    F+I+  SG+++    +D+E+ + Y + ++AQDGGS   ++  ++LI I
Sbjct: 2836 SFGTTATNVLRIFAINPKSGEITTKGNVDFEETKYYDISVQAQDGGS--LASHAKVLIQI 2893

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
             D NDNAP    +     VSE+ P G  +  ++A+D D G N E+     D +  G +  
Sbjct: 2894 LDENDNAPEISVTSITTPVSEDSPTGTVVALIKAHDLDSGENGEV-----DCEIVGVI-- 2946

Query: 308  PITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
            P  +   SG  Y   T+  LDRE   +Y L +  TD G P  S+  T             
Sbjct: 2947 PFKLLSSSGNFYKIITTSTLDREKTPRYNLTIHTTDKGSPTLSSLKTIRLDILDINDNPP 3006

Query: 365  XFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTR-----GRFSITSQ 417
             F    Y   + E+  PG  + ++ A D D  E+ ++ Y I   NT         SI S 
Sbjct: 3007 KFEKSNYVAYVTENNQPGASIYSIQAIDEDTEENGKVVYSIFTNNTEKFPSFSYISINSV 3066

Query: 418  NGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYT 475
             G    +    LD + +  + L ++A+D G   ++ T +++I +TD N+  PVF    Y 
Sbjct: 3067 TGGEKKSTDTSLDRETQSNHELILTASDGGNPVQTGTTLIKITVTDFNDNFPVFTQEVYK 3126

Query: 476  ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
             ++ E+ PI +TVL V+A+D D GINAQ+TYS S+  +N    H  + F INP  G ITT
Sbjct: 3127 VNIHENIPINSTVLRVNASDKDAGINAQVTYSFSTSANN---VH--RIFSINPNNGEITT 3181

Query: 536  N-KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
                LDRE    Y +T+ A D G P LS    + + V D+NDN P F++  Y A + E+ 
Sbjct: 3182 KASTLDREKTPHYNITIQATDKGSPPLSSKKTIRLDVSDINDNPPKFEKSNYVAYVTENN 3241

Query: 595  LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS---FVIDPASGVIRTNKALDRESVA 651
              G+S+  + A D D   NG++ Y +     E  S     I+P +GVI   ++ D E   
Sbjct: 3242 QPGSSIFSIKAIDKDTEENGKVVYSISNNTVEFSSVSYISINPVTGVIYALQSFDYEQDR 3301

Query: 652  THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711
               ++ +A D G+P  +S+ IV+I + D ND+ PVF  +     I EN PI +T+  + A
Sbjct: 3302 EFLIQIMAKDSGSPSLNSSAIVNITVTDFNDNFPVFTQEVYKVNIHENIPINSTVLHVNA 3361

Query: 712  HDPDEGPNAVVHYSIK--GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
             D DEG NA + YS      +    F +  + G    E+     LD E     Y + I+A
Sbjct: 3362 SDKDEGINAQITYSFSTTSANVLRMFYINPQNG----EIKIKGTLDRERS-SHYNITIQA 3416

Query: 770  A---SPPL--WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVT 824
                SPPL  W  + +E+L  D+NDN+PV +    I    ++  P      + A D D  
Sbjct: 3417 TDKGSPPLSSWKTIALEVL--DINDNSPVFEKSTYIAYVPENNQPGASIYSIQAIDKDTE 3474

Query: 825  D--KLQYRILSGNNANL-----ILLNETTG 847
            +  KL Y I++ N   L     I +N  TG
Sbjct: 3475 ENGKLFYSIITSNTEELSSTSYISINPVTG 3504



 Score =  374 bits (920), Expect = e-101
 Identities = 261/810 (32%), Positives = 403/810 (49%), Gaps = 59/810 (7%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            I+ QI V D ND+ PVF  + Y+ ++ E     +TVL + A+D+D G NA++ Y+     
Sbjct: 2782 INIQITVTDFNDNFPVFTQEVYKVNIHENIPIHSTVLQVNASDKDEGINAQITYSFGTTA 2841

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
             + L                  +F I+ +SG + T+ ++D E+   Y + V+A D  S  
Sbjct: 2842 TNVLR-----------------IFAINPKSGEITTKGNVDFEETKYYDISVQAQDGGS-- 2882

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
               L+S A + + I+D+NDN P+ S  + T  V ED S T   V+A IKA D D G N  
Sbjct: 2883 ---LASHAKVLIQILDENDNAPEISVTSITTPVSED-SPTGT-VVALIKAHDLDSGENGE 2937

Query: 187  IRYAIIGGNTQMQFSIDSLSGD---VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
            +   I+G    + F + S SG+   +    TLD E+   Y L I   D GSP+ S+   +
Sbjct: 2938 VDCEIVG---VIPFKLLSSSGNFYKIITTSTLDREKTPRYNLTIHTTDKGSPTLSSLKTI 2994

Query: 244  LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
             ++I D+NDN P+F  S +   V+EN   G SI  +QA D D   N ++ Y++    +T 
Sbjct: 2995 RLDILDINDNPPKFEKSNYVAYVTENNQPGASIYSIQAIDEDTEENGKVVYSI----FTN 3050

Query: 304  NVD-LP----ITIDPRSGWVY--TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
            N +  P    I+I+  +G     T   LDRETQ+ ++L++TA+DGG+P ++ T       
Sbjct: 3051 NTEKFPSFSYISINSVTGGEKKSTDTSLDRETQSNHELILTASDGGNPVQTGTTLIKITV 3110

Query: 357  XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH----YEITGGNTRGRF 412
                     F    Y+V + E+ P  + V+ + A+D D          +  +  N    F
Sbjct: 3111 TDFNDNFPVFTQEVYKVNIHENIPINSTVLRVNASDKDAGINAQVTYSFSTSANNVHRIF 3170

Query: 413  SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFE 470
            SI   NG  + T A  LD ++   Y +T+ ATD G    S    ++++++D N+  P FE
Sbjct: 3171 SINPNNGE-ITTKASTLDREKTPHYNITIQATDKGSPPLSSKKTIRLDVSDINDNPPKFE 3229

Query: 471  NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV-INPQ 529
             + Y A V E+   G+++  + A D D   N ++ YS    ISN  V      ++ INP 
Sbjct: 3230 KSNYVAYVTENNQPGSSIFSIKAIDKDTEENGKVVYS----ISNNTVEFSSVSYISINPV 3285

Query: 530  TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589
            TG I   +  D E    +L+ + A+D G PSL+ +  V I+V D NDN PVF Q++Y  N
Sbjct: 3286 TGVIYALQSFDYEQDREFLIQIMAKDSGSPSLNSSAIVNITVTDFNDNFPVFTQEVYKVN 3345

Query: 590  IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE-GSFVIDPASGVIRTNKALDRE 648
            I E+  + ++V  V A+D D G+N +I Y            F I+P +G I+    LDRE
Sbjct: 3346 IHENIPINSTVLHVNASDKDEGINAQITYSFSTTSANVLRMFYINPQNGEIKIKGTLDRE 3405

Query: 649  SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
              + +++   A D G+PP SS   + +++ DIND+ PVFE      Y+ EN+  G +I  
Sbjct: 3406 RSSHYNITIQATDKGSPPLSSWKTIALEVLDINDNSPVFEKSTYIAYVPENNQPGASIYS 3465

Query: 709  IRAHDPDEGPNAVVHYS-IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
            I+A D D   N  + YS I    +  S +           +      DYE  R ++E+ I
Sbjct: 3466 IQAIDKDTEENGKLFYSIITSNTEELSSTSYISINPVTGVIYAQRSFDYEQDR-EFEIQI 3524

Query: 768  RA---ASPPLWNDVRVEILVTDVNDNAPVM 794
             A    SPPL +   V I V D NDN+P +
Sbjct: 3525 IAKDNGSPPLNSSTIVRICVVDQNDNSPTV 3554



 Score =  359 bits (884), Expect = 5e-97
 Identities = 263/879 (29%), Positives = 413/879 (46%), Gaps = 49/879 (5%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I +LD ND+ P   +      V E ++ GT V+ L A D+D G NA++ Y+    +    
Sbjct: 2571 IQILDENDNPPEVSLTSITNPVSEESAPGT-VVALIANDKDEGINAQITYSFSATSKQAS 2629

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F I+  SG + T+ ++D EK   Y + V+A       S   
Sbjct: 2630 RS-----------------FAINAISGEIKTKENIDFEKTKYYEISVQARISFDGGSPMQ 2672

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            + TA I + + D NDN+P F ++ YTVS++E+I +  N  +  + A D D G NS I Y+
Sbjct: 2673 TGTALIRITVTDMNDNFPIFGQEVYTVSINENIPL--NSTVLCVSANDKDQGINSQITYS 2730

Query: 191  IIGGNTQ--MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
                + Q    FSI+S +G++   + LD+E+ ++Y + ++A+       S    + I + 
Sbjct: 2731 FSATSKQASRSFSINSETGEIKTKENLDFEKTKNYEISVQAKIQKHHILS-LINIQITVT 2789

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            D NDN P F   +++ ++ EN+PI  ++++V A D DEG+NA++TY+        NV   
Sbjct: 2790 DFNDNFPVFTQEVYKVNIHENIPIHSTVLQVNASDKDEGINAQITYSFGTT--ATNVLRI 2847

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
              I+P+SG + T G +D E    Y + V A DGG    ++ A                  
Sbjct: 2848 FAINPKSGEITTKGNVDFEETKYYDISVQAQDGGS--LASHAKVLIQILDENDNAPEISV 2905

Query: 369  GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGL-ITV 425
                  ++ED P GT V  + A D D  E+  +  EI G      F + S +G    I  
Sbjct: 2906 TSITTPVSEDSPTGTVVALIKAHDLDSGENGEVDCEIVGVIP---FKLLSSSGNFYKIIT 2962

Query: 426  AQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
               LD ++  RY LT+  TD G    S    ++++I D N+  P FE + Y A V E+  
Sbjct: 2963 TSTLDREKTPRYNLTIHTTDKGSPTLSSLKTIRLDILDINDNPPKFEKSNYVAYVTENNQ 3022

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA--ITTNKLLDR 541
             G ++  + A D D   N ++ YS+ +  +N           IN  TG    +T+  LDR
Sbjct: 3023 PGASIYSIQAIDEDTEENGKVVYSIFT--NNTEKFPSFSYISINSVTGGEKKSTDTSLDR 3080

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
            ET S + L +TA DGG P  + TT ++I+V D NDN PVF Q++Y  NI E+  + ++V 
Sbjct: 3081 ETQSNHELILTASDGGNPVQTGTTLIKITVTDFNDNFPVFTQEVYKVNIHENIPINSTVL 3140

Query: 602  QVGATDADVGLNGRIHYELDPK-DREEGSFVIDPASGVIRTN-KALDRESVATHDLKAVA 659
            +V A+D D G+N ++ Y      +     F I+P +G I T    LDRE    +++   A
Sbjct: 3141 RVNASDKDAGINAQVTYSFSTSANNVHRIFSINPNNGEITTKASTLDREKTPHYNITIQA 3200

Query: 660  IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
             D G+PP SS   + + + DIND+PP FE      Y++EN+  G++I  I+A D D   N
Sbjct: 3201 TDKGSPPLSSKKTIRLDVSDINDNPPKFEKSNYVAYVTENNQPGSSIFSIKAIDKDTEEN 3260

Query: 720  AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR--AASPPLWND 777
              V YSI       S             +  +   DYE  R+    ++   + SP L + 
Sbjct: 3261 GKVVYSISNNTVEFSSVSYISINPVTGVIYALQSFDYEQDREFLIQIMAKDSGSPSLNSS 3320

Query: 778  VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPAYDAD--VTDKLQYRI--L 832
              V I VTD NDN PV    ++   N  +  P+      V A D D  +  ++ Y     
Sbjct: 3321 AIVNITVTDFNDNFPVFTQ-EVYKVNIHENIPINSTVLHVNASDKDEGINAQITYSFSTT 3379

Query: 833  SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            S N   +  +N   G + +   L+        + +  TD
Sbjct: 3380 SANVLRMFYINPQNGEIKIKGTLDRERSSHYNITIQATD 3418



 Score =  355 bits (872), Expect = 1e-95
 Identities = 250/828 (30%), Positives = 408/828 (49%), Gaps = 69/828 (8%)

Query: 99   LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158
            ++T ++LDREK + Y + + ATD+ SP    LSS   I ++I+D NDN P F +  Y V 
Sbjct: 1337 IITSSALDREKASWYNITILATDRGSP---ELSSRKFIRLDILDVNDNPPIFIKSVYNVY 1393

Query: 159  VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQ-----MQFSIDSLSGDVSLVK 213
            + E+        I +I A D D+G N+ + Y+I   NT+       FSI+  +G +   +
Sbjct: 1394 LPENN--LPGASIYRIHALDLDMGDNAKVIYSISNTNTEDFPVSSYFSINIETGVLYAQR 1451

Query: 214  TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIG 273
            + D+EQ + + + I A DGG+P R+ T  + + + D NDN P F   +++ S+SEN PI 
Sbjct: 1452 SFDHEQDKEFHMHIAASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISENTPIN 1511

Query: 274  YSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQ 333
             +++RV A D DEG NA++TY+ +            +I+P SG + T   LDRE Q  ++
Sbjct: 1512 STVLRVNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEITTKKPLDREAQTSHE 1571

Query: 334  LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393
            L++TA+DGG+P R+ TA               F    Y V ++E+   G+ V+     +A
Sbjct: 1572 LILTASDGGNPVRTGTALIQIIVTDANDNLPVFTEVLYTVSISENTAVGSVVL---CVNA 1628

Query: 394  DEDNRLHYEITGGNTRG-RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT 452
              + ++ Y I+  NT    FSI  +   G++   Q  D++Q +++ + + A D+G  S T
Sbjct: 1629 SSNAKITYSISETNTMSPYFSINIET--GVLYAQQSFDYEQHKQFEMEIMAKDNGFPSMT 1686

Query: 453  A--------MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS-------- 496
            +        + ++ +TDAN+ APVF    YT S+ E+AP+   VL V+ATD         
Sbjct: 1687 SNTTLLIHIIDRVVVTDANDNAPVFTEEVYTVSISENAPVNAIVLCVNATDKDEVLHVNA 1746

Query: 497  ---DVGINAQITYS-LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552
               D G NAQITYS + + +S+         F IN +TG +   +  D E    + + + 
Sbjct: 1747 TDRDEGTNAQITYSFIKTSVSS--------YFSINIETGVLYAQRSFDYEQDKEFHMHIA 1798

Query: 553  ARDGGVPSLSDTTD------VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
            A+D G PSLS  T       +++ + DVNDN PVF++ LYT  + E+ L G S+  V AT
Sbjct: 1799 AKDNGSPSLSSNTTLSSRKFIKLDISDVNDNPPVFRKSLYTTYLPENNLPGASIYTVHAT 1858

Query: 607  DADVGLNGRIHYELDPKDREE----GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
            D D G N ++ Y +   + E+      F I+  +GV+   ++ D E      ++      
Sbjct: 1859 DVDSGDNAKLIYSISNANTEDFPVSSYFSINIETGVLYAQRSFDYEQQKEFQMQITQGRS 1918

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
            G       +   + I D ND+ PVF  D     ++EN P+ +T+  + A D DEG NA +
Sbjct: 1919 G-----HLMSFRVVITDANDNFPVFSKDVYKTTVNENMPVNSTVISVTASDKDEGTNAQI 1973

Query: 723  HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEI 782
             YS     +++ F++    G  +     + D + ES  +         +P       ++I
Sbjct: 1974 TYSFIQLSETSPFTISQHTGEIRTSQAPL-DRETESIHELVLTAFDGGNPVQTGTAIIKI 2032

Query: 783  LVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPAYDADVTDKLQ---YRILSGNNA- 837
            +V+D NDNAP+    ++   +  +  PV     RV A D D     Q   Y   S   A 
Sbjct: 2033 IVSDFNDNAPIFTQ-EVYTVSLNENIPVNSTILRVSANDKDEGSNSQITYYFAASSKQAM 2091

Query: 838  NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG---VNEIKAMMQL 882
            N  +++  +G +     L+    K   + V   DG   V+  K ++Q+
Sbjct: 2092 NTFIIDSISGEVKTKENLDFEKIKHYEISVQAKDGGGLVSHAKILIQI 2139



 Score =  348 bits (856), Expect = 1e-93
 Identities = 261/916 (28%), Positives = 442/916 (48%), Gaps = 88/916 (9%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++++LD ND+ P+F    Y   + E    G ++  + A D D+G NA+V Y+I       
Sbjct: 1372 RLDILDVNDNPPIFIKSVYNVYLPENNLPGASIYRIHALDLDMGDNAKVIYSI-----SN 1426

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             N ED           V   F I+  +G L  + S D E+   + + + A+D  +PV   
Sbjct: 1427 TNTED---------FPVSSYFSINIETGVLYAQRSFDHEQDKEFHMHIAASDGGTPVR-- 1475

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             + TA I V + D NDN P F+++ Y VS+ E+  +  N  + ++ A+D D G N+ I Y
Sbjct: 1476 -TGTALIRVIVTDANDNTPVFTQEVYKVSISENTPI--NSTVLRVNASDMDEGTNAQITY 1532

Query: 190  AI----IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
            +     +       FSI+  SG+++  K LD E   S+ L++ A DGG+P R+ T  + I
Sbjct: 1533 SFSRTSVNSLHASMFSINPTSGEITTKKPLDREAQTSHELILTASDGGNPVRTGTALIQI 1592

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
             + D NDN P F   L+  S+SEN  +G  ++ V A       NA++TY++++   T  +
Sbjct: 1593 IVTDANDNLPVFTEVLYTVSISENTAVGSVVLCVNA-----SSNAKITYSISE---TNTM 1644

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT------XXXXXXXX 359
                +I+  +G +Y     D E   ++++ + A D G P  ++  T              
Sbjct: 1645 SPYFSINIETGVLYAQQSFDYEQHKQFEMEIMAKDNGFPSMTSNTTLLIHIIDRVVVTDA 1704

Query: 360  XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT----GGNTRGRFSI- 414
                  F    Y V ++E+ P    V+ + ATD DE   LH   T    G N +  +S  
Sbjct: 1705 NDNAPVFTEEVYTVSISENAPVNAIVLCVNATDKDE--VLHVNATDRDEGTNAQITYSFI 1762

Query: 415  -TSQNG-------RGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAM-----VQIN 458
             TS +         G++   +  D++Q++ + + ++A D+G     S+T +     ++++
Sbjct: 1763 KTSVSSYFSINIETGVLYAQRSFDYEQDKEFHMHIAAKDNGSPSLSSNTTLSSRKFIKLD 1822

Query: 459  ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518
            I+D N+  PVF  + YT  + E+   G ++  V ATD D G NA++ YS+S+  +N    
Sbjct: 1823 ISDVNDNPPVFRKSLYTTYLPENNLPGASIYTVHATDVDSGDNAKLIYSISN--ANTEDF 1880

Query: 519  HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT-ARDGGVPSLSDTTDVEISVVDVNDN 577
                 F IN +TG +   +  D E    + + +T  R G + S        + + D NDN
Sbjct: 1881 PVSSYFSINIETGVLYAQRSFDYEQQKEFQMQITQGRSGHLMSF------RVVITDANDN 1934

Query: 578  EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637
             PVF + +Y   + E+  V ++V  V A+D D G N +I Y       E   F I   +G
Sbjct: 1935 FPVFSKDVYKTTVNENMPVNSTVISVTASDKDEGTNAQITYSFIQLS-ETSPFTISQHTG 1993

Query: 638  VIRTNKA-LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696
             IRT++A LDRE+ + H+L   A DGG P Q+ T I+ I + D ND+ P+F  +  T  +
Sbjct: 1994 EIRTSQAPLDRETESIHELVLTAFDGGNPVQTGTAIIKIIVSDFNDNAPIFTQEVYTVSL 2053

Query: 697  SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS--NSFSLETRQGSDKAELVTMVDL 754
            +EN P+ +TI  + A+D DEG N+ + Y          N+F +++  G    E+ T  +L
Sbjct: 2054 NENIPVNSTILRVSANDKDEGSNSQITYYFAASSKQAMNTFIIDSISG----EVKTKENL 2109

Query: 755  DYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GP 812
            D+E   K YE+ ++A     L +  ++ I + D NDN PV    ++   +  +  P+   
Sbjct: 2110 DFEK-IKHYEISVQAKDGGGLVSHAKILIQIIDFNDNLPVFSQ-EVYKVSINENIPINST 2167

Query: 813  FGRVPAYDAD--VTDKLQYRILSGNN--ANLILLNETTGSMTLSPQLNTNVPKLATMEVS 868
               V A D D  +  +++Y   + +    N  ++N  +G++     L+    KL  + V 
Sbjct: 2168 ILYVSANDKDEGINSQIRYYFSTSSKQILNTFIINSISGAIMTKENLDFEKTKLYEISVQ 2227

Query: 869  VTDG---VNEIKAMMQ 881
              DG   V+  K ++Q
Sbjct: 2228 AKDGGGLVSHAKVLIQ 2243



 Score =  347 bits (854), Expect = 2e-93
 Identities = 272/933 (29%), Positives = 442/933 (47%), Gaps = 64/933 (6%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            I  ++ V D ND++PVF  + Y  S+ E A     VL + ATD+D     EV   + +  
Sbjct: 1695 IIDRVVVTDANDNAPVFTEEVYTVSISENAPVNAIVLCVNATDKD-----EV---LHVNA 1746

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
             D     +A          V   F I+  +G L  + S D E+   + + + A D  SP 
Sbjct: 1747 TDRDEGTNAQITYSFIKTSVSSYFSINIETGVLYAQRSFDYEQDKEFHMHIAAKDNGSPS 1806

Query: 127  ---SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183
               +  LSS   I ++I D NDN P F +  YT  + E+        I  + ATD D G 
Sbjct: 1807 LSSNTTLSSRKFIKLDISDVNDNPPVFRKSLYTTYLPENN--LPGASIYTVHATDVDSGD 1864

Query: 184  NSAIRYAIIGGNTQ-----MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238
            N+ + Y+I   NT+       FSI+  +G +   ++ DYEQ + +++ I     G     
Sbjct: 1865 NAKLIYSISNANTEDFPVSSYFSINIETGVLYAQRSFDYEQQKEFQMQITQGRSG----- 1919

Query: 239  NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
            +     + I D NDN P F   +++ +V+EN+P+  +++ V A D DEG NA++TY+   
Sbjct: 1920 HLMSFRVVITDANDNFPVFSKDVYKTTVNENMPVNSTVISVTASDKDEGTNAQITYSFIQ 1979

Query: 299  KDYTGNVDLPITIDPRSGWVYTS-GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357
               T     P TI   +G + TS   LDRET++ ++L++TA DGG+P ++ TA       
Sbjct: 1980 LSETS----PFTISQHTGEIRTSQAPLDRETESIHELVLTAFDGGNPVQTGTAIIKIIVS 2035

Query: 358  XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSIT 415
                    F    Y V L E+ P  + ++ ++A D DE  ++++ Y     + +   +  
Sbjct: 2036 DFNDNAPIFTQEVYTVSLNENIPVNSTILRVSANDKDEGSNSQITYYFAASSKQAMNTFI 2095

Query: 416  SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYT 475
              +  G +   + LDF++ + Y ++V A D GG    A + I I D N+  PVF    Y 
Sbjct: 2096 IDSISGEVKTKENLDFEKIKHYEISVQAKDGGGLVSHAKILIQIIDFNDNLPVFSQEVYK 2155

Query: 476  ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
             S+ E+ PI +T+L VSA D D GIN+QI Y  S+  S++ + +    F+IN  +GAI T
Sbjct: 2156 VSINENIPINSTILYVSANDKDEGINSQIRYYFST--SSKQILN---TFIINSISGAIMT 2210

Query: 536  NKLLDRETMSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
             + LD E    Y ++V A+D GG+ S +      + V D+NDN PVFK   Y A I E+ 
Sbjct: 2211 KENLDFEKTKLYEISVQAKDGGGLVSHAKVLIQTLDVSDINDNPPVFKYPNYLAYIPENN 2270

Query: 595  LVGTSVSQVGATDADVGLNGRIHY---ELDPKDREEGSFV-IDPASGVIRTNKALDRESV 650
              G S+  + A D D   N ++ Y    ++  +    S++ I+P +GVI   ++ D E  
Sbjct: 2271 QPGASIYSIQAIDNDSEENAKLIYSIINMNTGEPSPSSYISINPVTGVIYAQRSFDYEQD 2330

Query: 651  ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF-----ESDCLTFY--ISENSPIG 703
                ++ +A D G+PP +S+VIV I + D ND+ P+      ++     Y  +  +S  G
Sbjct: 2331 REFQIQIMAKDNGSPPLNSSVIVTICVTDQNDNSPLVLYPSADAGGSAAYEMVPFSSEQG 2390

Query: 704  TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY 763
            T + ++ A D D G NA + Y      +++ F ++        ELV    LD E+    Y
Sbjct: 2391 TLVTKVVAVDADSGHNAWLSYHFLQDSETSYFVID-----QYTELVLKTSLDREN-ENFY 2444

Query: 764  ELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPA 818
            E+V+ A    +P       + I VTD NDN P+     +++  N          +     
Sbjct: 2445 EIVLTAFDGGNPMQTGTALIRITVTDANDNFPMFSQEIYKVSINENMPLNSTVLYVSASD 2504

Query: 819  YDADVTDKLQYRILSGNN--ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG---V 873
             D  +  +L Y   S +    N   +N  +G +     L+    K   + V   DG   +
Sbjct: 2505 KDEGINSQLTYSFSSASKQATNAFAINPQSGEVITKDILDFEKMKNYEIAVQAKDGGGLI 2564

Query: 874  NEIKAMMQ-LSVRLITEEMLLNSITVRLNDMTA 905
            +  K ++Q L       E+ L SIT  +++ +A
Sbjct: 2565 SHAKVLIQILDENDNPPEVSLTSITNPVSEESA 2597



 Score =  332 bits (817), Expect = 6e-89
 Identities = 255/806 (31%), Positives = 397/806 (49%), Gaps = 65/806 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I ++D ND+ PVF  + Y+ S+ E     +T+L + A D+D G N+++ Y     +   L
Sbjct: 2137 IQIIDFNDNLPVFSQEVYKVSINENIPINSTILYVSANDKDEGINSQIRYYFSTSSKQIL 2196

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N                  F I+  SGA++T+ +LD EK   Y + V+A D    VS   
Sbjct: 2197 N-----------------TFIINSISGAIMTKENLDFEKTKLYEISVQAKDGGGLVSHAK 2239

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
                T+ V+  D NDN P F    Y   + E+        I  I+A D D   N+ + Y+
Sbjct: 2240 VLIQTLDVS--DINDNPPVFKYPNYLAYIPENNQ--PGASIYSIQAIDNDSEENAKLIYS 2295

Query: 191  IIGGNT-----QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
            II  NT         SI+ ++G +   ++ DYEQ R +++ I A+D GSP  +++  + I
Sbjct: 2296 IINMNTGEPSPSSYISINPVTGVIYAQRSFDYEQDREFQIQIMAKDNGSPPLNSSVIVTI 2355

Query: 246  NIRDVNDNAPR-FYTSLFQ--ESVSENVPI----GYSIVRVQAYDADEGVNAELTYTMTD 298
             + D NDN+P   Y S      +  E VP     G  + +V A DAD G NA L+Y    
Sbjct: 2356 CVTDQNDNSPLVLYPSADAGGSAAYEMVPFSSEQGTLVTKVVAVDADSGHNAWLSYHFLQ 2415

Query: 299  KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358
               T        ID  +  V  +  LDRE +  Y++++TA DGG+P ++ TA        
Sbjct: 2416 DSETSY----FVIDQYTELVLKTS-LDRENENFYEIVLTAFDGGNPMQTGTALIRITVTD 2470

Query: 359  XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGR--FSI 414
                   F    Y+V + E+ P  + V+ ++A+D DE  +++L Y  +  + +    F+I
Sbjct: 2471 ANDNFPMFSQEIYKVSINENMPLNSTVLYVSASDKDEGINSQLTYSFSSASKQATNAFAI 2530

Query: 415  TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPY 474
              Q+G   +     LDF++ + Y + V A D GG    A V I I D N+  P       
Sbjct: 2531 NPQSGE--VITKDILDFEKMKNYEIAVQAKDGGGLISHAKVLIQILDENDNPPEVSLTSI 2588

Query: 475  TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
            T  V E++  GT V ++ A D D GINAQITYS S+  S +A     + F IN  +G I 
Sbjct: 2589 TNPVSEESAPGTVVALI-ANDKDEGINAQITYSFSA-TSKQA----SRSFAINAISGEIK 2642

Query: 535  TNKLLDRETMSGYLLTVTAR---DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
            T + +D E    Y ++V AR   DGG P  + T  + I+V D+NDN P+F Q++YT +I 
Sbjct: 2643 TKENIDFEKTKYYEISVQARISFDGGSPMQTGTALIRITVTDMNDNFPIFGQEVYTVSIN 2702

Query: 592  EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG-SFVIDPASGVIRTNKALDRESV 650
            E+  + ++V  V A D D G+N +I Y      ++   SF I+  +G I+T + LD E  
Sbjct: 2703 ENIPLNSTVLCVSANDKDQGINSQITYSFSATSKQASRSFSINSETGEIKTKENLDFEKT 2762

Query: 651  ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710
              +++ +V          S + + I + D ND+ PVF  +     I EN PI +T+ ++ 
Sbjct: 2763 KNYEI-SVQAKIQKHHILSLINIQITVTDFNDNFPVFTQEVYKVNIHENIPIHSTVLQVN 2821

Query: 711  AHDPDEGPNAVVHYSIKGGDDSN---SFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
            A D DEG NA + YS  G   +N    F++  + G    E+ T  ++D+E   K Y++ +
Sbjct: 2822 ASDKDEGINAQITYSF-GTTATNVLRIFAINPKSG----EITTKGNVDFEE-TKYYDISV 2875

Query: 768  RAA-SPPLWNDVRVEILVTDVNDNAP 792
            +A     L +  +V I + D NDNAP
Sbjct: 2876 QAQDGGSLASHAKVLIQILDENDNAP 2901



 Score =  321 bits (788), Expect = 2e-85
 Identities = 254/831 (30%), Positives = 385/831 (46%), Gaps = 64/831 (7%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++++ D ND++PVF    Y + V   +  G  +  + A D D G NA + Y +   +  +
Sbjct: 464  KLDISDVNDNAPVFTKSSYVSMVPVASEQGALITKVVAVDADSGHNAWLSYHVVQGSEPS 523

Query: 70   LNPEDAXXXXXXXXXXVQDVFR------------IDG----RSGALLTRASL----DREK 109
            L                QD  R             DG    RSG  L R ++    D   
Sbjct: 524  LFSISQNTGEIRTSRVFQDKDRETQTIHELILTASDGGNPVRSGTALIRIAVTDANDNLP 583

Query: 110  VAR---YTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVT 166
            V     Y V +        V D+ S    I ++I D NDN P F++ +Y   + E+    
Sbjct: 584  VFTQEVYKVSISTLIALIEVHDQDSDIKLIKLDISDVNDNAPVFTKSSYVAYIAENNLAG 643

Query: 167  DNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ-----FSIDSLSGDVSLVKTLDYEQVR 221
             +  I +I+A+D D G N+ I Y+I   +T+       FSI+  +G +   K LD E   
Sbjct: 644  AS--IYRIQASDIDAGDNAKIIYSIYNTDTEDYSMSSFFSINIETGVLYAQKPLDRETQS 701

Query: 222  SYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA 281
             + L++ A DGG+P R+ T  + I + D NDN P F   +++ S+SEN PI  S++ + A
Sbjct: 702  IHELILTASDGGNPLRTGTALIRIIVTDSNDNLPVFTQEVYKVSISENAPINSSVIILTA 761

Query: 282  YDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATD 340
             D DEG NA++TY+++             I+P  G +    + LDRETQ  ++L++TA+D
Sbjct: 762  TDKDEGTNAQITYSISKTSENNFYTSVFNINPVMGEITIKEKPLDRETQKDHELILTASD 821

Query: 341  GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNR 398
            GGDP ++ TA               F    Y+V ++E+ P  + V+ + ATD DE  + +
Sbjct: 822  GGDPVKTGTAIIRIIVTDANDNLPVFTKAVYKVSISENIPINSSVLHVNATDRDEGTNAQ 881

Query: 399  LHYEI--TGGNT--RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM 454
            + Y    T  N      FSI   NG   I   Q LDF+  R Y ++V ATD GG    + 
Sbjct: 882  ITYSFIKTSENDIHSPMFSINQINGE--IKTLQKLDFELTRNYEMSVQATDGGGFVAHSK 939

Query: 455  VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
            V + I + N+ AP       +  + ED+  GT + ++   D D G N +    L      
Sbjct: 940  VLLEIINENDNAPEITMTSVSTPIPEDSEPGTVIALIKVHDHDSGENGEAECHLLGSPPF 999

Query: 515  EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
            + V+     +        I T  +LDRE +  Y +T+ A D G P LS    + + + DV
Sbjct: 1000 QLVSTSSSYY-------RIITTSVLDREKVQLYNITILANDKGSPQLSSRKSILLDISDV 1052

Query: 575  NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE----EGSF 630
            NDN PVF +  Y A + E+ L G S+ +V A+D D G N ++ Y +   + E       F
Sbjct: 1053 NDNPPVFLKSRYIAYLPENNLPGASIYKVQASDLDTGENSKVIYSVFNTNTEAFPVSSYF 1112

Query: 631  VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND-SPPVFES 689
             I+  +GV+   ++ D E      +   A D G P  SS   + I+I D ND +P +F  
Sbjct: 1113 SINIETGVLYAQRSFDYEQHKEFAMHVQAKDNGYPSLSSNATLIIRIIDQNDNAPKMFIK 1172

Query: 690  DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD-----SNSFSLETRQGSD 744
               T Y+ EN+  G TI  I A D D G NA V YSI   +      S+ FS+    G  
Sbjct: 1173 SAYTIYLPENNLPGATIYRIHALDLDMGDNAKVIYSISNTNTEDFPVSSYFSINIETG-- 1230

Query: 745  KAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792
               L      DYE   K++ + I A    SP L ++  + I + D NDNAP
Sbjct: 1231 --VLYAQRSFDYEQD-KEFHMHIAAKDNGSPSLSSNTTLIIRIMDQNDNAP 1278



 Score =  313 bits (768), Expect = 5e-83
 Identities = 234/820 (28%), Positives = 383/820 (46%), Gaps = 68/820 (8%)

Query: 5    FCIHQQI--NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
            F  H ++   +++ ND++P   M      + E +  GT +  +K  D D G+N E E   
Sbjct: 934  FVAHSKVLLEIINENDNAPEITMTSVSTPIPEDSEPGTVIALIKVHDHDSGENGEAE--C 991

Query: 63   ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122
             L+ +                      +RI       +T + LDREKV  Y + + A D+
Sbjct: 992  HLLGSPPFQ----------LVSTSSSYYRI-------ITTSVLDREKVQLYNITILANDK 1034

Query: 123  ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
             SP   +LSS  +I ++I D NDN P F +  Y   + E  +      I K++A+D D G
Sbjct: 1035 GSP---QLSSRKSILLDISDVNDNPPVFLKSRYIAYLPE--NNLPGASIYKVQASDLDTG 1089

Query: 183  ANSAIRYAIIGGNTQ-----MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237
             NS + Y++   NT+       FSI+  +G +   ++ DYEQ + + + ++A+D G PS 
Sbjct: 1090 ENSKVIYSVFNTNTEAFPVSSYFSINIETGVLYAQRSFDYEQHKEFAMHVQAKDNGYPSL 1149

Query: 238  SNTTQLLINIRDVNDNAPR-FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
            S+   L+I I D NDNAP+ F  S +   + EN   G +I R+ A D D G NA++ Y++
Sbjct: 1150 SSNATLIIRIIDQNDNAPKMFIKSAYTIYLPENNLPGATIYRIHALDLDMGDNAKVIYSI 1209

Query: 297  TDKDYTGNVDLPI----TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352
            ++   T   D P+    +I+  +G +Y     D E   ++ + + A D G P  S+  T 
Sbjct: 1210 SN---TNTEDFPVSSYFSINIETGVLYAQRSFDYEQDKEFHMHIAAKDNGSPSLSSNTTL 1266

Query: 353  XXXXXXXXXXXXXFMPGQYEV--ELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG 410
                          +    E    L  +  P   +  L +      + +++ +  GN   
Sbjct: 1267 IIRIMDQNDNAPKILYPSTESGDSLLFEMVPFASIEALISIQEKSGHPVYFSLRWGNPTE 1326

Query: 411  RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPV 468
                     R  I  +  LD ++   Y +T+ ATD G    S    ++++I D N+  P+
Sbjct: 1327 HLKTAFIFYR--IITSSALDREKASWYNITILATDRGSPELSSRKFIRLDILDVNDNPPI 1384

Query: 469  FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528
            F  + Y   + E+   G ++  + A D D+G NA++ YS+S+  +N         F IN 
Sbjct: 1385 FIKSVYNVYLPENNLPGASIYRIHALDLDMGDNAKVIYSISN--TNTEDFPVSSYFSINI 1442

Query: 529  QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588
            +TG +   +  D E    + + + A DGG P  + T  + + V D NDN PVF Q++Y  
Sbjct: 1443 ETGVLYAQRSFDHEQDKEFHMHIAASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKV 1502

Query: 589  NIMEDALVGTSVSQVGATDADVGLNGRIHYEL---DPKDREEGSFVIDPASGVIRTNKAL 645
            +I E+  + ++V +V A+D D G N +I Y              F I+P SG I T K L
Sbjct: 1503 SISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEITTKKPL 1562

Query: 646  DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
            DRE+  +H+L   A DGG P ++ T ++ I + D ND+ PVF     T  ISEN+ +G+ 
Sbjct: 1563 DREAQTSHELILTASDGGNPVRTGTALIQIIVTDANDNLPVFTEVLYTVSISENTAVGSV 1622

Query: 706  IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765
            +  + A       NA + YSI    ++N+ S       +   L      DYE   K++E+
Sbjct: 1623 VLCVNA-----SSNAKITYSI---SETNTMSPYFSINIETGVLYAQQSFDYEQ-HKQFEM 1673

Query: 766  VIRAAS---PPLWNDVRV------EILVTDVNDNAPVMKD 796
             I A     P + ++  +       ++VTD NDNAPV  +
Sbjct: 1674 EIMAKDNGFPSMTSNTTLLIHIIDRVVVTDANDNAPVFTE 1713



 Score =  311 bits (763), Expect = 2e-82
 Identities = 257/913 (28%), Positives = 412/913 (45%), Gaps = 91/913 (9%)

Query: 11   INVLDCNDHSP-VFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            I ++D ND++P +F    Y   + E    G T+  + A D D+G NA+V Y+I       
Sbjct: 1157 IRIIDQNDNAPKMFIKSAYTIYLPENNLPGATIYRIHALDLDMGDNAKVIYSI-----SN 1211

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             N ED           V   F I+  +G L  + S D E+   + + + A D  SP    
Sbjct: 1212 TNTED---------FPVSSYFSINIETGVLYAQRSFDYEQDKEFHMHIAAKDNGSP---S 1259

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKA-TDADVGANSAIR 188
            LSS  T+ + I+D NDN P+     Y  +   D  + +    A I+A       +   + 
Sbjct: 1260 LSSNTTLIIRIMDQNDNAPKI---LYPSTESGDSLLFEMVPFASIEALISIQEKSGHPVY 1316

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            +++  GN         +   +     LD E+   Y + I A D GSP  S+   + ++I 
Sbjct: 1317 FSLRWGNPTEHLKTAFIFYRIITSSALDREKASWYNITILATDRGSPELSSRKFIRLDIL 1376

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            DVNDN P F  S++   + EN   G SI R+ A D D G NA++ Y++++   T   D P
Sbjct: 1377 DVNDNPPIFIKSVYNVYLPENNLPGASIYRIHALDLDMGDNAKVIYSISN---TNTEDFP 1433

Query: 309  I----TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
            +    +I+  +G +Y     D E   ++ + + A+DGG P R+ TA              
Sbjct: 1434 VSSYFSINIETGVLYAQRSFDHEQDKEFHMHIAASDGGTPVRTGTALIRVIVTDANDNTP 1493

Query: 365  XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT------RGRFSITSQN 418
             F    Y+V ++E+ P  + V+ + A+D DE        +   T         FSI   +
Sbjct: 1494 VFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTS 1553

Query: 419  GRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTA 476
            G   IT  +PLD + +  + L ++A+D G   R+ TA++QI +TDAN+  PVF    YT 
Sbjct: 1554 GE--ITTKKPLDREAQTSHELILTASDGGNPVRTGTALIQIIVTDANDNLPVFTEVLYTV 1611

Query: 477  SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
            S+ E+  +G+ VL V+A+      NA+ITYS+S   +N    +    F IN +TG +   
Sbjct: 1612 SISENTAVGSVVLCVNASS-----NAKITYSISE--TNTMSPY----FSINIETGVLYAQ 1660

Query: 537  KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV------DVNDNEPVFKQQLYTANI 590
            +  D E    + + + A+D G PS++  T + I ++      D NDN PVF +++YT +I
Sbjct: 1661 QSFDYEQHKQFEMEIMAKDNGFPSMTSNTTLLIHIIDRVVVTDANDNAPVFTEEVYTVSI 1720

Query: 591  MEDALVGT-----------SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639
             E+A V              V  V ATD D G N +I Y    K      F I+  +GV+
Sbjct: 1721 SENAPVNAIVLCVNATDKDEVLHVNATDRDEGTNAQITYSF-IKTSVSSYFSINIETGVL 1779

Query: 640  RTNKALDRESVATHDLKAVAIDGGTPPQSSTV------IVHIKIEDINDSPPVFESDCLT 693
               ++ D E      +   A D G+P  SS         + + I D+ND+PPVF     T
Sbjct: 1780 YAQRSFDYEQDKEFHMHIAAKDNGSPSLSSNTTLSSRKFIKLDISDVNDNPPVFRKSLYT 1839

Query: 694  FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD-----SNSFSLETRQGSDKAEL 748
             Y+ EN+  G +I  + A D D G NA + YSI   +      S+ FS+    G     L
Sbjct: 1840 TYLPENNLPGASIYTVHATDVDSGDNAKLIYSISNANTEDFPVSSYFSINIETG----VL 1895

Query: 749  VTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCF 808
                  DYE  ++    + +  S  L   +   +++TD NDN PV     +      +  
Sbjct: 1896 YAQRSFDYEQQKEFQMQITQGRSGHL---MSFRVVITDANDNFPVFSK-DVYKTTVNENM 1951

Query: 809  PV-GPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSM-TLSPQLNTNVPKLAT 864
            PV      V A D D     ++ Y  +  +  +   +++ TG + T    L+     +  
Sbjct: 1952 PVNSTVISVTASDKDEGTNAQITYSFIQLSETSPFTISQHTGEIRTSQAPLDRETESIHE 2011

Query: 865  MEVSVTDGVNEIK 877
            + ++  DG N ++
Sbjct: 2012 LVLTAFDGGNPVQ 2024



 Score =  308 bits (757), Expect = 1e-81
 Identities = 248/917 (27%), Positives = 430/917 (46%), Gaps = 81/917 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I V D ND+ PVF  + Y+ S+ E A   ++V+ L ATD+D G NA++ Y+I   + + 
Sbjct: 724  RIIVTDSNDNLPVFTQEVYKVSISENAPINSSVIILTATDKDEGTNAQITYSISKTSENN 783

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS-LDREKVARYTVLVKATDQASPVSD 128
                               VF I+   G +  +   LDRE    + +++ A+D   PV  
Sbjct: 784  F---------------YTSVFNINPVMGEITIKEKPLDRETQKDHELILTASDGGDPVK- 827

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
              + TA I + + D NDN P F++  Y VS+ E+I +  N  +  + ATD D G N+ I 
Sbjct: 828  --TGTAIIRIIVTDANDNLPVFTKAVYKVSISENIPI--NSSVLHVNATDRDEGTNAQIT 883

Query: 189  YAIIGGNTQ----MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
            Y+ I  +        FSI+ ++G++  ++ LD+E  R+Y + ++A DGG     +  ++L
Sbjct: 884  YSFIKTSENDIHSPMFSINQINGEIKTLQKLDFELTRNYEMSVQATDGGGFVAHS--KVL 941

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
            + I + NDNAP    +     + E+   G  I  ++ +D D G N E      +    G+
Sbjct: 942  LEIINENDNAPEITMTSVSTPIPEDSEPGTVIALIKVHDHDSGENGE-----AECHLLGS 996

Query: 305  VDLPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
                +     S + + T+  LDRE    Y + + A D G P  S+  +            
Sbjct: 997  PPFQLVSTSSSYYRIITTSVLDREKVQLYNITILANDKGSPQLSSRKSILLDISDVNDNP 1056

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG-- 419
              F+  +Y   L E+  PG  +  + A+D D  E++++ Y +   NT   F ++S     
Sbjct: 1057 PVFLKSRYIAYLPENNLPGASIYKVQASDLDTGENSKVIYSVFNTNTEA-FPVSSYFSIN 1115

Query: 420  --RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAP-VFENAPY 474
               G++   +  D++Q + + + V A D+G    S  A + I I D N+ AP +F  + Y
Sbjct: 1116 IETGVLYAQRSFDYEQHKEFAMHVQAKDNGYPSLSSNATLIIRIIDQNDNAPKMFIKSAY 1175

Query: 475  TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
            T  + E+   G T+  + A D D+G NA++ YS+S+  + +        F IN +TG + 
Sbjct: 1176 TIYLPENNLPGATIYRIHALDLDMGDNAKVIYSISNTNTEDFPV--SSYFSINIETGVLY 1233

Query: 535  TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
              +  D E    + + + A+D G PSLS  T + I ++D NDN P     LY +    D+
Sbjct: 1234 AQRSFDYEQDKEFHMHIAAKDNGSPSLSSNTTLIIRIMDQNDNAPKI---LYPSTESGDS 1290

Query: 595  LVGTSVSQVGATDADVGLNGR----IHYEL---DPKDREEGSFVIDPASGVIRTNKALDR 647
            L+   V    + +A + +  +    +++ L   +P +  + +F+       I T+ ALDR
Sbjct: 1291 LLFEMVP-FASIEALISIQEKSGHPVYFSLRWGNPTEHLKTAFIFYR----IITSSALDR 1345

Query: 648  ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
            E  + +++  +A D G+P  SS   + + I D+ND+PP+F       Y+ EN+  G +I 
Sbjct: 1346 EKASWYNITILATDRGSPELSSRKFIRLDILDVNDNPPIFIKSVYNVYLPENNLPGASIY 1405

Query: 708  EIRAHDPDEGPNAVVHYSIKGGDD-----SNSFSLETRQGSDKAELVTMVDLDYESPRKK 762
             I A D D G NA V YSI   +      S+ FS+    G     L      D+E   K+
Sbjct: 1406 RIHALDLDMGDNAKVIYSISNTNTEDFPVSSYFSINIETGV----LYAQRSFDHEQD-KE 1460

Query: 763  YELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPA 818
            + + I A+   +P       + ++VTD NDN PV    ++   +  +  P+     RV A
Sbjct: 1461 FHMHIAASDGGTPVRTGTALIRVIVTDANDNTPVFTQ-EVYKVSISENTPINSTVLRVNA 1519

Query: 819  YDAD------VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
             D D      +T       ++  +A++  +N T+G +T    L+        + ++ +DG
Sbjct: 1520 SDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEITTKKPLDREAQTSHELILTASDG 1579

Query: 873  VNEIKAMMQLSVRLITE 889
             N ++    L   ++T+
Sbjct: 1580 GNPVRTGTALIQIIVTD 1596



 Score =  277 bits (680), Expect = 2e-72
 Identities = 189/627 (30%), Positives = 306/627 (48%), Gaps = 36/627 (5%)

Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS 164
           LDRE +  + +++ ATD  +P   + + TA + + + D NDN P F+++ Y +S+ E   
Sbjct: 1   LDRETLNFHELILTATDGGNP---KRTGTALLRIIVTDYNDNVPVFTQQVYKISISESAP 57

Query: 165 VTDNPVIAKIKATDADVGANSAIRYAII-----GGNTQMQFSIDSLSGDVSLVKTLDYEQ 219
           +  N  +  + ATD D G N  I Y+         +TQM F+I+  +G++     L++E 
Sbjct: 58  I--NSTVTVVTATDKDDGTNGHITYSFSRTAENAFHTQM-FNINPANGEIKTKGHLNFEV 114

Query: 220 VRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRV 279
            + Y + ++A+DGG     +  ++LI I D NDNAP    +     + E+   G  I  +
Sbjct: 115 TKHYEMSVQAKDGGGLLAQS--KVLIEIIDENDNAPEISIASLSTPIPEDSAPGTLIALI 172

Query: 280 QAYDADEGVNAELT-YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA 338
           + +D D G N E   + +    +            R   +  +G LDRE    Y + + A
Sbjct: 173 EVHDQDSGENGEAECHILGSSPFHKFRKWKPLSSSRYYKIVNTGSLDRELVPWYNITILA 232

Query: 339 TDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR 398
           TD G P  S                  F+   Y+  ++E+ P  T V+ + ATD  +  +
Sbjct: 233 TDRGSPQLSTMKFIKLDISDVNDNPPMFVKSVYKASISENSPVNTTVLYVNATDKVKHQK 292

Query: 399 LHYEITGGN--TRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAM 454
           + + +   +      FSI  + G  ++   +  D++Q + + + ++A+D G   RS TA+
Sbjct: 293 IAFIMDNEDFPISSYFSINIETG--VLYAQRSFDYEQVKEFQIQITASDGGNPVRSGTAL 350

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           ++I +TD+N+  PVF    Y  S+ E+ PI +TVL V+ATD D G NAQI YS S    N
Sbjct: 351 IRIAVTDSNDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQIMYSFSKTSGN 410

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG---VPSLSDTTDVEISV 571
                H   F IN  +G I T +  + E    Y ++V A+DGG     S      +++ +
Sbjct: 411 NL---HTSMFSINYTSGEIKTKQNFNFEAKKFYEISVQAKDGGGFVAHSKILIKLIKLDI 467

Query: 572 VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631
            DVNDN PVF +  Y + +   +  G  +++V A DAD G N  + Y +  +  E   F 
Sbjct: 468 SDVNDNAPVFTKSSYVSMVPVASEQGALITKVVAVDADSGHNAWLSYHV-VQGSEPSLFS 526

Query: 632 IDPASGVIRTNKAL---DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688
           I   +G IRT++     DRE+   H+L   A DGG P +S T ++ I + D ND+ PVF 
Sbjct: 527 ISQNTGEIRTSRVFQDKDRETQTIHELILTASDGGNPVRSGTALIRIAVTDANDNLPVFT 586

Query: 689 SDCLTFYISENSPIGTTIGEIRAHDPD 715
            +   + +S    I T I  I  HD D
Sbjct: 587 QE--VYKVS----ISTLIALIEVHDQD 607



 Score =  250 bits (613), Expect = 3e-64
 Identities = 175/596 (29%), Positives = 285/596 (47%), Gaps = 29/596 (4%)

Query: 215 LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY 274
           LD E +  + L++ A DGG+P R+ T  L I + D NDN P F   +++ S+SE+ PI  
Sbjct: 1   LDRETLNFHELILTATDGGNPKRTGTALLRIIVTDYNDNVPVFTQQVYKISISESAPINS 60

Query: 275 SIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQL 334
           ++  V A D D+G N  +TY+ +             I+P +G + T G L+ E    Y++
Sbjct: 61  TVTVVTATDKDDGTNGHITYSFSRTAENAFHTQMFNINPANGEIKTKGHLNFEVTKHYEM 120

Query: 335 LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394
            V A DGG     A +                        + ED  PGT +  +   D D
Sbjct: 121 SVQAKDGGG--LLAQSKVLIEIIDENDNAPEISIASLSTPIPEDSAPGTLIALIEVHDQD 178

Query: 395 --EDNRLHYEITGGNTRGRF----SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG 448
             E+      I G +   +F     ++S     ++     LD +    Y +T+ ATD G 
Sbjct: 179 SGENGEAECHILGSSPFHKFRKWKPLSSSRYYKIVNTGS-LDRELVPWYNITILATDRGS 237

Query: 449 RSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506
              + M  ++++I+D N+  P+F  + Y AS+ E++P+ TTVL V+ATD     + +I +
Sbjct: 238 PQLSTMKFIKLDISDVNDNPPMFVKSVYKASISENSPVNTTVLYVNATDKVK--HQKIAF 295

Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566
            + +E  +  ++ +   F IN +TG +   +  D E +  + + +TA DGG P  S T  
Sbjct: 296 IMDNE--DFPISSY---FSINIETGVLYAQRSFDYEQVKEFQIQITASDGGNPVRSGTAL 350

Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP---K 623
           + I+V D NDN PVF Q++Y  +I E+  + ++V  V ATD D G N +I Y        
Sbjct: 351 IRIAVTDSNDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQIMYSFSKTSGN 410

Query: 624 DREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV---IVHIKIEDI 680
           +     F I+  SG I+T +  + E+   +++   A DGG     S +   ++ + I D+
Sbjct: 411 NLHTSMFSINYTSGEIKTKQNFNFEAKKFYEISVQAKDGGGFVAHSKILIKLIKLDISDV 470

Query: 681 NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR 740
           ND+ PVF        +   S  G  I ++ A D D G NA + Y +  G + + FS+   
Sbjct: 471 NDNAPVFTKSSYVSMVPVASEQGALITKVVAVDADSGHNAWLSYHVVQGSEPSLFSISQN 530

Query: 741 QGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPV 793
            G  +   V   D D E+ +  +EL++ A+   +P       + I VTD NDN PV
Sbjct: 531 TGEIRTSRV-FQDKDRET-QTIHELILTASDGGNPVRSGTALIRIAVTDANDNLPV 584



 Score =  246 bits (601), Expect = 9e-63
 Identities = 182/600 (30%), Positives = 291/600 (48%), Gaps = 54/600 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +I V D ND+ PVF  Q Y+ S+ E A   +TV  + ATD+D G N  + Y+      + 
Sbjct: 30  RIIVTDYNDNVPVFTQQVYKISISESAPINSTVTVVTATDKDDGTNGHITYSFSRTAENA 89

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            + +               +F I+  +G + T+  L+ E    Y + V+A D        
Sbjct: 90  FHTQ---------------MFNINPANGEIKTKGHLNFEVTKHYEMSVQAKDGGG----- 129

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           L + + + + IID+NDN P+ S  + +  + ED +     +IA I+  D D G N     
Sbjct: 130 LLAQSKVLIEIIDENDNAPEISIASLSTPIPEDSA--PGTLIALIEVHDQDSGENGEAEC 187

Query: 190 AIIGGNTQMQF---SIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
            I+G +   +F      S S    +V T  LD E V  Y + I A D GSP  S    + 
Sbjct: 188 HILGSSPFHKFRKWKPLSSSRYYKIVNTGSLDRELVPWYNITILATDRGSPQLSTMKFIK 247

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           ++I DVNDN P F  S+++ S+SEN P+  +++ V A   D+  + ++ + M ++D+  +
Sbjct: 248 LDISDVNDNPPMFVKSVYKASISENSPVNTTVLYVNA--TDKVKHQKIAFIMDNEDFPIS 305

Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
               I I+  +G +Y     D E   ++Q+ +TA+DGG+P RS TA              
Sbjct: 306 SYFSINIE--TGVLYAQRSFDYEQVKEFQIQITASDGGNPVRSGTALIRIAVTDSNDNLP 363

Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH----YEITGGNT--RGRFSITSQN 418
            F    Y+V ++E+ P  + V+T+ ATD DE         +  T GN      FSI   +
Sbjct: 364 VFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQIMYSFSKTSGNNLHTSMFSINYTS 423

Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGG-----RSDTAMVQINITDANNYAPVFENAP 473
           G   I   Q  +F+ ++ Y ++V A D GG     +    +++++I+D N+ APVF  + 
Sbjct: 424 GE--IKTKQNFNFEAKKFYEISVQAKDGGGFVAHSKILIKLIKLDISDVNDNAPVFTKSS 481

Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
           Y + V   +  G  +  V A D+D G NA ++Y +               F I+  TG I
Sbjct: 482 YVSMVPVASEQGALITKVVAVDADSGHNAWLSYHVVQ-------GSEPSLFSISQNTGEI 534

Query: 534 TTNKLL---DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590
            T+++    DRET + + L +TA DGG P  S T  + I+V D NDN PVF Q++Y  +I
Sbjct: 535 RTSRVFQDKDRETQTIHELILTASDGGNPVRSGTALIRIAVTDANDNLPVFTQEVYKVSI 594



 Score =  225 bits (549), Expect = 2e-56
 Identities = 166/580 (28%), Positives = 276/580 (47%), Gaps = 39/580 (6%)

Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383
           LDRET   ++L++TATDGG+P R+ TA               F    Y++ ++E  P  +
Sbjct: 1   LDRETLNFHELILTATDGGNPKRTGTALLRIIVTDYNDNVPVFTQQVYKISISESAPINS 60

Query: 384 PVVTLTATDADEDNRLHYEITGGNTRGR------FSITSQNGRGLITVAQPLDFKQERRY 437
            V  +TATD D+    H   +   T         F+I   NG   I     L+F+  + Y
Sbjct: 61  TVTVVTATDKDDGTNGHITYSFSRTAENAFHTQMFNINPANGE--IKTKGHLNFEVTKHY 118

Query: 438 VLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497
            ++V A D GG    + V I I D N+ AP    A  +  + ED+  GT + ++   D D
Sbjct: 119 EMSVQAKDGGGLLAQSKVLIEIIDENDNAPEISIASLSTPIPEDSAPGTLIALIEVHDQD 178

Query: 498 VGINAQITYSLSSEISNEAVAHHDQQF--VINPQTGAITTNKLLDRETMSGYLLTVTARD 555
            G N +        I   +  H  +++  + + +   I     LDRE +  Y +T+ A D
Sbjct: 179 SGENGEA----ECHILGSSPFHKFRKWKPLSSSRYYKIVNTGSLDRELVPWYNITILATD 234

Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615
            G P LS    +++ + DVNDN P+F + +Y A+I E++ V T+V  V ATD     + +
Sbjct: 235 RGSPQLSTMKFIKLDISDVNDNPPMFVKSVYKASISENSPVNTTVLYVNATDKVK--HQK 292

Query: 616 IHYELDPKDREEGS-FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674
           I + +D +D    S F I+  +GV+   ++ D E V    ++  A DGG P +S T ++ 
Sbjct: 293 IAFIMDNEDFPISSYFSINIETGVLYAQRSFDYEQVKEFQIQITASDGGNPVRSGTALIR 352

Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734
           I + D ND+ PVF  +     ISEN PI +T+  + A D DEG NA + YS      +N 
Sbjct: 353 IAVTDSNDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQIMYSFSKTSGNNL 412

Query: 735 FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP---PLWNDVRVEIL---VTDVN 788
            +          E+ T  + ++E+ +K YE+ ++A         + + ++++   ++DVN
Sbjct: 413 HTSMFSINYTSGEIKTKQNFNFEA-KKFYEISVQAKDGGGFVAHSKILIKLIKLDISDVN 471

Query: 789 DNAPVMKDFQIIFNNYKDCFPVGP-----FGRVPAYDADVTDK--LQYRILSGNNANLIL 841
           DNAPV        ++Y    PV         +V A DAD      L Y ++ G+  +L  
Sbjct: 472 DNAPVFTK-----SSYVSMVPVASEQGALITKVVAVDADSGHNAWLSYHVVQGSEPSLFS 526

Query: 842 LNETTGSMTLSPQLNTNVPKLATME---VSVTDGVNEIKA 878
           +++ TG +  S        +  T+    ++ +DG N +++
Sbjct: 527 ISQNTGEIRTSRVFQDKDRETQTIHELILTASDGGNPVRS 566



 Score =  182 bits (443), Expect = 1e-43
 Identities = 140/498 (28%), Positives = 220/498 (44%), Gaps = 33/498 (6%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I ++D ND++P   +      + E ++ GT +  ++  DQD G+N E E  I       L
Sbjct: 138 IEIIDENDNAPEISIASLSTPIPEDSAPGTLIALIEVHDQDSGENGEAECHI-------L 190

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                              ++I       +   SLDRE V  Y + + ATD+ SP   +L
Sbjct: 191 GSSPFHKFRKWKPLSSSRYYKI-------VNTGSLDRELVPWYNITILATDRGSP---QL 240

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           S+   I ++I D NDN P F +  Y  S+ E+  V  N  +  + ATD       A    
Sbjct: 241 STMKFIKLDISDVNDNPPMFVKSVYKASISENSPV--NTTVLYVNATDKVKHQKIAFIMD 298

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
                    FSI+  +G +   ++ DYEQV+ +++ I A DGG+P RS T  + I + D 
Sbjct: 299 NEDFPISSYFSINIETGVLYAQRSFDYEQVKEFQIQITASDGGNPVRSGTALIRIAVTDS 358

Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
           NDN P F   +++ S+SEN+PI  +++ V A D DEG NA++ Y+ +            +
Sbjct: 359 NDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQIMYSFSKTSGNNLHTSMFS 418

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD---PPRSATATXXXXXXXXXXXXXXFM 367
           I+  SG + T    + E +  Y++ V A DGG      +                   F 
Sbjct: 419 INYTSGEIKTKQNFNFEAKKFYEISVQAKDGGGFVAHSKILIKLIKLDISDVNDNAPVFT 478

Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGR-GLIT 424
              Y   +      G  +  + A DAD  +   L Y +  G+    FSI+   G      
Sbjct: 479 KSSYVSMVPVASEQGALITKVVAVDADSGHNAWLSYHVVQGSEPSLFSISQNTGEIRTSR 538

Query: 425 VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
           V Q  D + +  + L ++A+D G   RS TA+++I +TDAN+  PVF    Y  S     
Sbjct: 539 VFQDKDRETQTIHELILTASDGGNPVRSGTALIRIAVTDANDNLPVFTQEVYKVS----- 593

Query: 483 PIGTTVLVVSATDSDVGI 500
            I T + ++   D D  I
Sbjct: 594 -ISTLIALIEVHDQDSDI 610



 Score =  147 bits (355), Expect = 6e-33
 Identities = 102/326 (31%), Positives = 165/326 (50%), Gaps = 17/326 (5%)

Query: 562 SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621
           SD   +++ + DVNDN PVF +  Y A I E+ L G S+ ++ A+D D G N +I Y + 
Sbjct: 608 SDIKLIKLDISDVNDNAPVFTKSSYVAYIAENNLAGASIYRIQASDIDAGDNAKIIYSIY 667

Query: 622 PKDREEGS----FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
             D E+ S    F I+  +GV+   K LDRE+ + H+L   A DGG P ++ T ++ I +
Sbjct: 668 NTDTEDYSMSSFFSINIETGVLYAQKPLDRETQSIHELILTASDGGNPLRTGTALIRIIV 727

Query: 678 EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL 737
            D ND+ PVF  +     ISEN+PI +++  + A D DEG NA + YSI    ++N ++ 
Sbjct: 728 TDSNDNLPVFTQEVYKVSISENAPINSSVIILTATDKDEGTNAQITYSISKTSENNFYTS 787

Query: 738 ETRQGSDKAEL-VTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPV 793
                    E+ +    LD E+ +K +EL++ A+    P       + I+VTD NDN PV
Sbjct: 788 VFNINPVMGEITIKEKPLDRET-QKDHELILTASDGGDPVKTGTAIIRIIVTDANDNLPV 846

Query: 794 MKDFQIIFNNYKDCFPV-GPFGRVPAYDAD--VTDKLQYRIL--SGNNAN--LILLNETT 846
                +   +  +  P+      V A D D     ++ Y  +  S N+ +  +  +N+  
Sbjct: 847 FTK-AVYKVSISENIPINSSVLHVNATDRDEGTNAQITYSFIKTSENDIHSPMFSINQIN 905

Query: 847 GSMTLSPQLNTNVPKLATMEVSVTDG 872
           G +    +L+  + +   M V  TDG
Sbjct: 906 GEIKTLQKLDFELTRNYEMSVQATDG 931


>UniRef50_UPI0000F1F871 Cluster: PREDICTED: similar to FAT tumor
            suppressor homolog 4; n=2; Danio rerio|Rep: PREDICTED:
            similar to FAT tumor suppressor homolog 4 - Danio rerio
          Length = 2572

 Score =  376 bits (926), Expect = e-102
 Identities = 372/1351 (27%), Positives = 593/1351 (43%), Gaps = 145/1351 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND++P F    Y     E    G+ V  + ATD D G N ++ Y I   T    
Sbjct: 496  IFVTDINDNAPRFSKPSYYLDYPELTEIGSIVTQVSATDPDEGFNGKIFYFIRSQT---- 551

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
              E            ++   R    SG        +   V R++ +V A+D+   +   +
Sbjct: 552  --EYFRINSSSGEIFIKQQLRYQNSSGH-------NNINVNRHSFIVTASDRG--IKPLM 600

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA-DVGANSAIRY 189
            S T T+ +N++D NDN P F   +Y   V + + V     + K+ A D  D G NS I Y
Sbjct: 601  SET-TVMINVVDSNDNPPTFESPSYFTPVTKSVKVGTR--LLKVTAYDKKDFGLNSEIEY 657

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            AI GGN+  +F +D  +G V++  +L  +  + Y L I A D G+P  S+ T + I + +
Sbjct: 658  AISGGNSSNKFRLDKQTGSVTVASSLAADTNKVYLLEITASDKGNPPLSDRTTVKIAVTE 717

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG--VNAELTYTMTDKDYTGNVDL 307
             N + P F  +    +VSE + +G +I  + A D D+   +N  +TY ++    +GN D 
Sbjct: 718  ENHHTPEFSQNQVTVTVSEALTVGTAIRTLSARDKDKDKQMNGLITYNIS----SGNDDG 773

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
              ++  ++G +  +  LD ET+ K++L V+ATDGG   +++  T              F 
Sbjct: 774  LFSVHSQTGVLSLAKTLDYETKQKHELRVSATDGGWIAKTSYVTVNIQVTDVNDNPPVFD 833

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
            P +Y   + E+ P GT VV + ATD D   N L   +   +    F I    G  +IT  
Sbjct: 834  PVEYFPVVQENVPSGTTVVKMNATDKDSGSNALMAYVIQSSDSDLFIIDPNTG--IITTQ 891

Query: 427  QPLDFKQERRYVLTVSATD--SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
              LD++ ++ Y LTV A +     R   A V I +  AN Y P F +  Y   + E AP 
Sbjct: 892  GFLDYEAKQVYHLTVKAFNVPDEERCSFAYVNIQLKGANEYVPRFVSKQYYFEISEAAPK 951

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            GT V  V A+D D+G +  + Y +               F IN +TG I  +  LDRE  
Sbjct: 952  GTVVGEVFASDRDLGEDGVVYYLIFGRSRKRG-------FSINKKTGQIYVSGSLDREKE 1004

Query: 545  SGYLLTVTARDGGVPSLSDTTDV--EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
                L V A++ G    +D  +V   I+V+D ND  PVF Q+LY   + E    G  V+ 
Sbjct: 1005 EKISLKVLAKNAGSIRGADIDEVLVNITVLDAND-PPVFTQELYDVQVNEGLSPGGLVTF 1063

Query: 603  VGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
            V A D+D V    R  Y +   + E  +F I+P +G +     LDRE+V  ++L  +A+D
Sbjct: 1064 VSAEDSDSVPSWSRFTYAI-AANHERNTFTINPQTGQVSVASELDRETVPVYNLTILAVD 1122

Query: 662  GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY--ISENSPIGTTIGEIRAHDPDEGPN 719
             G+P  + + I+ + +EDIND+ P      +T Y  + EN   GT +  + + DPD  PN
Sbjct: 1123 SGSPAATGSAILIVTLEDINDNGPTL----VTTYGEVMENQRAGTPVMTLSSRDPDLAPN 1178

Query: 720  -AVVHYS-IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--PPLW 775
                 YS +  G  S+ F++     S   EL T  ++D E     Y  V+   S  P + 
Sbjct: 1179 QGPFTYSLVSTGAASSYFTI-----SPTGELTTSREVDREQISDFYLSVLIKDSGIPQMS 1233

Query: 776  NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGN 835
            +   V I V D NDN    +  +I  + + + FP G  G V   D D+ D  Q    S  
Sbjct: 1234 STGTVHIKVNDQNDNPSESRSVEIYVHYFGNMFPGGSLGVVKPQDPDIQDTFQ---CSLT 1290

Query: 836  NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE-IKAMMQLSVRLITEEMLLN 894
                +L +  TG+  L    + +      + V   DGV+  + + +++         + N
Sbjct: 1291 PPAALLFSIPTGTCDLISN-SRSTDGTFDLSVRSNDGVHSAVNSHVRVFFIGFNNATVDN 1349

Query: 895  SITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSAR 954
            SI +R+   +A  FLS     F+    + +      + I+ V +       + N +F   
Sbjct: 1350 SILIRVTTKSASDFLSNHYLSFLRIANSQLAGLGTGVQIYGVFE-------LNNSTF--- 1399

Query: 955  RPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECL 1014
                   V    S + +P+ +       +  L R + V++   D + C H PC N   C 
Sbjct: 1400 ---LTAAVKRGHSQYVNPSGVATFFQSIKEVLHRQSGVKIDSVDHDPCSHNPCQNGGSCK 1456

Query: 1015 TVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKA------------ 1062
              L  G       S  V+     P+  + C C  G+ G  CET + +             
Sbjct: 1457 RRLGVGPEMKTEESVPVILVSNQPLQPYACNCRPGYAGALCETDIDECQPTPCHNGGTCH 1516

Query: 1063 ------SCEV-DG-DGSIC-RSGSQCVARR-EGGILCQ------GCSIDAAYTTAV---C 1103
                  SC   DG  G  C R  ++C++   + G LCQ       C   + +       C
Sbjct: 1517 NLVGGFSCTCPDGFTGMACERDVNECLSNPCQNGALCQNYPGGFNCLCKSGFAGVFGKHC 1576

Query: 1104 ELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYN--GRYNERHDFLALELVS 1161
            EL +  F   S++ FP L   +  ++ +KFAT   + LL+YN   +  ++ +FLALE++ 
Sbjct: 1577 ELNSYGFEELSYMEFPSLDPNNN-YIYIKFATLKENALLMYNHDNQTGDKAEFLALEILE 1635

Query: 1162 SEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKVLSL 1221
               GR     +RFSF+LG G  ++     V DG +HTV         ++ +D C +    
Sbjct: 1636 ---GR-----MRFSFNLGSGAYKLMTSIRVSDGQFHTVIARRAGMAASLTIDLCGE---- 1683

Query: 1222 AGAADFGLKYACANFTRKVLPARCEIPTETCHR--FLDL-TGPLQIGGLPNIPS----SF 1274
                             +  P  C +     H    LD+    L +GG+ +I +    S 
Sbjct: 1684 -----------------EQEPGYCAVSNVAVHTDWILDVQPNRLSVGGVRSIEALLHRSG 1726

Query: 1275 QVKNKDFVGCISDFYIDHKFIDLNSYVADNG 1305
            QV   DFVGCI +F ++ + ++ +  +A +G
Sbjct: 1727 QVSTHDFVGCIMEFAVNGRPLEPSQALASHG 1757



 Score =  352 bits (865), Expect = 9e-95
 Identities = 250/804 (31%), Positives = 402/804 (50%), Gaps = 58/804 (7%)

Query: 86   VQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145
            + + F ID  SG L  R  LD E + +Y + ++A DQ  P     S+   + + ++D ND
Sbjct: 244  LDNAFHIDQLSGELSIRKPLDYENIEKYVLWIEARDQGFPP---YSAYEKVEIAVLDVND 300

Query: 146  NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205
            N+P F ++ +   + E++S      +  + A D D G N  + YAII GN +  F+I+  
Sbjct: 301  NHPVFEQEPFHAEILENLSPQR---VLVVSALDQDSGPNGQLEYAIIDGNKENSFNINRA 357

Query: 206  SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265
            +G++   + LD E+V  Y L ++A D G P +S   ++LI++ DVNDNAPRF + +F  +
Sbjct: 358  TGEIRTTRPLDREKVAQYSLRVKATDRGMPPKSTAVKVLISVLDVNDNAPRF-SKIFSAT 416

Query: 266  VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325
            V EN P+G+++ RV   D D G NA   Y++TD        LP  I P +G +  S  L+
Sbjct: 417  VPENAPVGFTVTRVTTTDEDAGANAISRYSITD------ASLPFIIHPSTGDITISRPLN 470

Query: 326  RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
            RE    Y   V+A D G    + +                F    Y ++  E    G+ V
Sbjct: 471  REDTDHYIAKVSAHDSG---WTVSTDVTIFVTDINDNAPRFSKPSYYLDYPELTEIGSIV 527

Query: 386  VTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE--------R 435
              ++ATD DE  + ++ Y I   +    F I S +G   I + Q L ++           
Sbjct: 528  TQVSATDPDEGFNGKIFYFIR--SQTEYFRINSSSGE--IFIKQQLRYQNSSGHNNINVN 583

Query: 436  RYVLTVSATDSGGR---SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492
            R+   V+A+D G +   S+T  V IN+ D+N+  P FE+  Y   V +   +GT +L V+
Sbjct: 584  RHSFIVTASDRGIKPLMSETT-VMINVVDSNDNPPTFESPSYFTPVTKSVKVGTRLLKVT 642

Query: 493  ATD-SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTV 551
            A D  D G+N++I Y++S         +   +F ++ QTG++T    L  +T   YLL +
Sbjct: 643  AYDKKDFGLNSEIEYAISG-------GNSSNKFRLDKQTGSVTVASSLAADTNKVYLLEI 695

Query: 552  TARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG 611
            TA D G P LSD T V+I+V + N + P F Q   T  + E   VGT++  + A D D  
Sbjct: 696  TASDKGNPPLSDRTTVKIAVTEENHHTPEFSQNQVTVTVSEALTVGTAIRTLSARDKDKD 755

Query: 612  --LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669
              +NG I Y +     ++G F +   +GV+   K LD E+   H+L+  A DGG   ++S
Sbjct: 756  KQMNGLITYNIS-SGNDDGLFSVHSQTGVLSLAKTLDYETKQKHELRVSATDGGWIAKTS 814

Query: 670  TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729
             V V+I++ D+ND+PPVF+       + EN P GTT+ ++ A D D G NA++ Y I+  
Sbjct: 815  YVTVNIQVTDVNDNPPVFDPVEYFPVVQENVPSGTTVVKMNATDKDSGSNALMAYVIQ-S 873

Query: 730  DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP---LWNDVRVEILVTD 786
             DS+ F ++   G     + T   LDYE+ ++ Y L ++A + P     +   V I +  
Sbjct: 874  SDSDLFIIDPNTGI----ITTQGFLDYEA-KQVYHLTVKAFNVPDEERCSFAYVNIQLKG 928

Query: 787  VNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADV-TDKLQYRILSGNNANL-ILLN 843
             N+  P     Q  F    +  P G   G V A D D+  D + Y ++ G +      +N
Sbjct: 929  ANEYVPRFVSKQYYF-EISEAAPKGTVVGEVFASDRDLGEDGVVYYLIFGRSRKRGFSIN 987

Query: 844  ETTGSMTLSPQLNTNVPKLATMEV 867
            + TG + +S  L+    +  +++V
Sbjct: 988  KKTGQIYVSGSLDREKEEKISLKV 1011



 Score =  344 bits (845), Expect = 2e-92
 Identities = 263/879 (29%), Positives = 419/879 (47%), Gaps = 65/879 (7%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I VLD ND+ PVFE + + A + E  S    VL + A DQD G N ++EY I     D 
Sbjct: 292  EIAVLDVNDNHPVFEQEPFHAEILENLSP-QRVLVVSALDQDSGPNGQLEYAI----IDG 346

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             N E++              F I+  +G + T   LDREKVA+Y++ VKATD+  P    
Sbjct: 347  -NKENS--------------FNINRATGEIRTTRPLDREKVAQYSLRVKATDRGMPPK-- 389

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             S+   + ++++D NDN P+FS K ++ +V E+  V     + ++  TD D GAN+  RY
Sbjct: 390  -STAVKVLISVLDVNDNAPRFS-KIFSATVPENAPV--GFTVTRVTTTDEDAGANAISRY 445

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            +I   +  + F I   +GD+++ + L+ E    Y   + A D G    + +T + I + D
Sbjct: 446  SIT--DASLPFIIHPSTGDITISRPLNREDTDHYIAKVSAHDSG---WTVSTDVTIFVTD 500

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY---TMTDKDYTGNVD 306
            +NDNAPRF    +     E   IG  + +V A D DEG N ++ Y   + T+     +  
Sbjct: 501  INDNAPRFSKPSYYLDYPELTEIGSIVTQVSATDPDEGFNGKIFYFIRSQTEYFRINSSS 560

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
              I I  +  +  +SG  +     ++  +VTA+D G  P  +  T              F
Sbjct: 561  GEIFIKQQLRYQNSSGHNNINVN-RHSFIVTASDRGIKPLMSETTVMINVVDSNDNPPTF 619

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADE---DNRLHYEITGGNTRGRFSITSQNGRGLI 423
                Y   + +    GT ++ +TA D  +   ++ + Y I+GGN+  +F +  Q G   +
Sbjct: 620  ESPSYFTPVTKSVKVGTRLLKVTAYDKKDFGLNSEIEYAISGGNSSNKFRLDKQTGS--V 677

Query: 424  TVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFED 481
            TVA  L     + Y+L ++A+D G    SD   V+I +T+ N++ P F     T +V E 
Sbjct: 678  TVASSLAADTNKVYLLEITASDKGNPPLSDRTTVKIAVTEENHHTPEFSQNQVTVTVSEA 737

Query: 482  APIGTTVLVVSATDSDVG--INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
              +GT +  +SA D D    +N  ITY++SS        + D  F ++ QTG ++  K L
Sbjct: 738  LTVGTAIRTLSARDKDKDKQMNGLITYNISS-------GNDDGLFSVHSQTGVLSLAKTL 790

Query: 540  DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
            D ET   + L V+A DGG  + +    V I V DVNDN PVF    Y   + E+   GT+
Sbjct: 791  DYETKQKHELRVSATDGGWIAKTSYVTVNIQVTDVNDNPPVFDPVEYFPVVQENVPSGTT 850

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
            V ++ ATD D G N  + Y +   D +   F+IDP +G+I T   LD E+   + L   A
Sbjct: 851  VVKMNATDKDSGSNALMAYVIQSSDSD--LFIIDPNTGIITTQGFLDYEAKQVYHLTVKA 908

Query: 660  IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
             +     + S   V+I+++  N+  P F S    F ISE +P GT +GE+ A D D G +
Sbjct: 909  FNVPDEERCSFAYVNIQLKGANEYVPRFVSKQYYFEISEAAPKGTVVGEVFASDRDLGED 968

Query: 720  AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL----W 775
             VV+Y I G      FS+  + G    ++     LD E   K    V+   +  +     
Sbjct: 969  GVVYYLIFGRSRKRGFSINKKTG----QIYVSGSLDREKEEKISLKVLAKNAGSIRGADI 1024

Query: 776  NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVT---DKLQYRIL 832
            ++V V I V D ND     ++   +  N +   P G    V A D+D      +  Y I 
Sbjct: 1025 DEVLVNITVLDANDPPVFTQELYDVQVN-EGLSPGGLVTFVSAEDSDSVPSWSRFTYAIA 1083

Query: 833  SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            + +  N   +N  TG ++++ +L+     +  + +   D
Sbjct: 1084 ANHERNTFTINPQTGQVSVASELDRETVPVYNLTILAVD 1122



 Score =  317 bits (778), Expect = 3e-84
 Identities = 261/865 (30%), Positives = 404/865 (46%), Gaps = 80/865 (9%)

Query: 28  YEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQ 87
           +  ++ E A +GT VL L ++D D+G N  + Y+        L+  D             
Sbjct: 3   FHTTIPEDAPTGTDVLLLNSSDSDVGLNGVISYS--------LSGGDGQ----------- 43

Query: 88  DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
             F I+  +G ++T + LDRE  A Y +LV A+D   P    LSS+AT+ V + D NDN 
Sbjct: 44  --FSINPSTGLIITSSLLDRETRASYQLLVVASDGGQPTP--LSSSATVSVVVADINDNP 99

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
           P+F    Y   +    S +   ++  +  TD D G+NS + Y++ G N++ +F ID + G
Sbjct: 100 PRFHHHPYVTHI--PASTSTGSLVFAVTVTDEDSGSNSQLHYSLTGRNSE-KFKIDPIRG 156

Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
            ++  + L      ++   +  +DGG+  ++++T + +      D  P         +  
Sbjct: 157 AITASEKLTGSSEVTF--TVHVKDGGTNPKTDSTTVTVRFVTGGD-FPHIKLKDKAFTFP 213

Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
           EN P    + +V       G    L+Y +     +GN+D    ID  SG +     LD E
Sbjct: 214 ENQPTNTIVTKVTGSSPRAG---PLSYYIA----SGNLDNAFHIDQLSGELSIRKPLDYE 266

Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAED-EPPGTPVV 386
              KY L + A D G PP SA                 F    +  E+ E+  P    VV
Sbjct: 267 NIEKYVLWIEARDQGFPPYSAYEKVEIAVLDVNDNHPVFEQEPFHAEILENLSPQRVLVV 326

Query: 387 TLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446
           +    D+  + +L Y I  GN    F+I    G   I   +PLD ++  +Y L V ATD 
Sbjct: 327 SALDQDSGPNGQLEYAIIDGNKENSFNINRATGE--IRTTRPLDREKVAQYSLRVKATDR 384

Query: 447 G--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504
           G   +S    V I++ D N+ AP F    ++A+V E+AP+G TV  V+ TD D G NA  
Sbjct: 385 GMPPKSTAVKVLISVLDVNDNAPRFSKI-FSATVPENAPVGFTVTRVTTTDEDAGANA-- 441

Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT 564
                  IS  ++      F+I+P TG IT ++ L+RE    Y+  V+A D G    + +
Sbjct: 442 -------ISRYSITDASLPFIIHPSTGDITISRPLNREDTDHYIAKVSAHDSG---WTVS 491

Query: 565 TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624
           TDV I V D+NDN P F +  Y  +  E   +G+ V+QV ATD D G NG+I Y +  + 
Sbjct: 492 TDVTIFVTDINDNAPRFSKPSYYLDYPELTEIGSIVTQVSATDPDEGFNGKIFYFI--RS 549

Query: 625 REEGSFVIDPASGVIRTNKAL--------DRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676
           + E  F I+ +SG I   + L        +  +V  H     A D G  P  S   V I 
Sbjct: 550 QTE-YFRINSSSGEIFIKQQLRYQNSSGHNNINVNRHSFIVTASDRGIKPLMSETTVMIN 608

Query: 677 IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD-PDEGPNAVVHYSIKGGDDSNSF 735
           + D ND+PP FES      ++++  +GT + ++ A+D  D G N+ + Y+I GG+ SN F
Sbjct: 609 VVDSNDNPPTFESPSYFTPVTKSVKVGTRLLKVTAYDKKDFGLNSEIEYAISGGNSSNKF 668

Query: 736 SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAP 792
            L+ + GS     VT+         K Y L I A+   +PPL +   V+I VT+ N + P
Sbjct: 669 RLDKQTGS-----VTVASSLAADTNKVYLLEITASDKGNPPLSDRTTVKIAVTEENHHTP 723

Query: 793 VMKDFQIIFNNYKDCFPVGPFGR-VPAYDAD----VTDKLQYRILSGNNANLILLNETTG 847
                Q+      +   VG   R + A D D    +   + Y I SGN+  L  ++  TG
Sbjct: 724 EFSQNQVTV-TVSEALTVGTAIRTLSARDKDKDKQMNGLITYNISSGNDDGLFSVHSQTG 782

Query: 848 SMTLSPQLNTNVPKLATMEVSVTDG 872
            ++L+  L+    +   + VS TDG
Sbjct: 783 VLSLAKTLDYETKQKHELRVSATDG 807



 Score =  302 bits (741), Expect = 1e-79
 Identities = 261/862 (30%), Positives = 387/862 (44%), Gaps = 88/862 (10%)

Query: 13  VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72
           V D ND+ P F    Y   +    S+G+ V  +  TD+D G N+++ Y++        N 
Sbjct: 92  VADINDNPPRFHHHPYVTHIPASTSTGSLVFAVTVTDEDSGSNSQLHYSLT-----GRNS 146

Query: 73  EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132
           E                F+ID   GA+     L       +TV VK     +P +D    
Sbjct: 147 EK---------------FKIDPIRGAITASEKLTGSSEVTFTVHVK-DGGTNPKTD---- 186

Query: 133 TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192
           + T+ V  +   D +P    K    +  E+     N ++ K+  +    G  S   Y I 
Sbjct: 187 STTVTVRFVTGGD-FPHIKLKDKAFTFPENQPT--NTIVTKVTGSSPRAGPLS---YYIA 240

Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252
            GN    F ID LSG++S+ K LDYE +  Y L I A+D G P  S   ++ I + DVND
Sbjct: 241 SGNLDNAFHIDQLSGELSIRKPLDYENIEKYVLWIEARDQGFPPYSAYEKVEIAVLDVND 300

Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312
           N P F    F   + EN+     ++ V A D D G N +L Y + D    GN +    I+
Sbjct: 301 NHPVFEQEPFHAEILENLS-PQRVLVVSALDQDSGPNGQLEYAIID----GNKENSFNIN 355

Query: 313 PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE 372
             +G + T+  LDRE  A+Y L V ATD G PP+S TA                    + 
Sbjct: 356 RATGEIRTTRPLDREKVAQYSLRVKATDRGMPPKS-TAVKVLISVLDVNDNAPRFSKIFS 414

Query: 373 VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQN-------GRGLITV 425
             + E+ P G  V  +T TD D          G N   R+SIT  +         G IT+
Sbjct: 415 ATVPENAPVGFTVTRVTTTDED---------AGANAISRYSITDASLPFIIHPSTGDITI 465

Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
           ++PL+ +    Y+  VSA DSG    T  V I +TD N+ AP F    Y     E   IG
Sbjct: 466 SRPLNREDTDHYIAKVSAHDSGWTVSTD-VTIFVTDINDNAPRFSKPSYYLDYPELTEIG 524

Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
           + V  VSATD D G N +I Y + S+          + F IN  +G I   + L  +  S
Sbjct: 525 SIVTQVSATDPDEGFNGKIFYFIRSQ---------TEYFRINSSSGEIFIKQQLRYQNSS 575

Query: 546 G--------YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
           G        +   VTA D G+  L   T V I+VVD NDN P F+   Y   + +   VG
Sbjct: 576 GHNNINVNRHSFIVTASDRGIKPLMSETTVMINVVDSNDNPPTFESPSYFTPVTKSVKVG 635

Query: 598 TSVSQVGATD-ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
           T + +V A D  D GLN  I Y +         F +D  +G +    +L  ++   + L+
Sbjct: 636 TRLLKVTAYDKKDFGLNSEIEYAIS-GGNSSNKFRLDKQTGSVTVASSLAADTNKVYLLE 694

Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
             A D G PP S    V I + + N   P F  + +T  +SE   +GT I  + A D D+
Sbjct: 695 ITASDKGNPPLSDRTTVKIAVTEENHHTPEFSQNQVTVTVSEALTVGTAIRTLSARDKDK 754

Query: 717 GP--NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL 774
               N ++ Y+I  G+D   FS+ ++ G     L     LDYE+ ++K+EL + +A+   
Sbjct: 755 DKQMNGLITYNISSGNDDGLFSVHSQTG----VLSLAKTLDYET-KQKHELRV-SATDGG 808

Query: 775 W----NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADV-TDKLQ 828
           W    + V V I VTDVNDN PV    +  F   ++  P G    ++ A D D  ++ L 
Sbjct: 809 WIAKTSYVTVNIQVTDVNDNPPVFDPVE-YFPVVQENVPSGTTVVKMNATDKDSGSNALM 867

Query: 829 YRILSGNNANLILLNETTGSMT 850
             ++  ++++L +++  TG +T
Sbjct: 868 AYVIQSSDSDLFIIDPNTGIIT 889



 Score =  285 bits (698), Expect = 2e-74
 Identities = 215/732 (29%), Positives = 350/732 (47%), Gaps = 42/732 (5%)

Query: 154 TYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVK 213
           ++  ++ ED + T   V+  + ++D+DVG N  I Y++ GG+ Q  FSI+  +G +    
Sbjct: 2   SFHTTIPED-APTGTDVLL-LNSSDSDVGLNGVISYSLSGGDGQ--FSINPSTGLIITSS 57

Query: 214 TLDYEQVRSYRLVIRAQDGGSPSR-SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI 272
            LD E   SY+L++ A DGG P+  S++  + + + D+NDN PRF+   +   +  +   
Sbjct: 58  LLDRETRASYQLLVVASDGGQPTPLSSSATVSVVVADINDNPPRFHHHPYVTHIPASTST 117

Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332
           G  +  V   D D G N++L Y++     TG       IDP  G +  S +L   ++  +
Sbjct: 118 GSLVFAVTVTDEDSGSNSQLHYSL-----TGRNSEKFKIDPIRGAITASEKLTGSSEVTF 172

Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392
              V   DGG  P++ + T               +  +      E++P  T +VT     
Sbjct: 173 --TVHVKDGGTNPKTDSTTVTVRFVTGGDFPHIKLKDK-AFTFPENQPTNT-IVTKVTGS 228

Query: 393 ADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT 452
           +     L Y I  GN    F I   +G   +++ +PLD++   +YVL + A D G    +
Sbjct: 229 SPRAGPLSYYIASGNLDNAFHIDQLSGE--LSIRKPLDYENIEKYVLWIEARDQGFPPYS 286

Query: 453 A--MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510
           A   V+I + D N+  PVFE  P+ A + E+      VLVVSA D D G N Q+ Y++  
Sbjct: 287 AYEKVEIAVLDVNDNHPVFEQEPFHAEILENLS-PQRVLVVSALDQDSGPNGQLEYAIID 345

Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570
                   + +  F IN  TG I T + LDRE ++ Y L V A D G+P  S    V IS
Sbjct: 346 -------GNKENSFNINRATGEIRTTRPLDREKVAQYSLRVKATDRGMPPKSTAVKVLIS 398

Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630
           V+DVNDN P F  ++++A + E+A VG +V++V  TD D G N    Y +         F
Sbjct: 399 VLDVNDNAPRF-SKIFSATVPENAPVGFTVTRVTTTDEDAGANAISRYSITDASL---PF 454

Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690
           +I P++G I  ++ L+RE    +  K  A D G    +    V I + DIND+ P F   
Sbjct: 455 IIHPSTGDITISRPLNREDTDHYIAKVSAHDSGWTVSTD---VTIFVTDINDNAPRFSKP 511

Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750
                  E + IG+ + ++ A DPDEG N  + Y I+   +    +  + +   K +L  
Sbjct: 512 SYYLDYPELTEIGSIVTQVSATDPDEGFNGKIFYFIRSQTEYFRINSSSGEIFIKQQLRY 571

Query: 751 MVDLDYESPR-KKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKD 806
                + +    ++  ++ A+     PL ++  V I V D NDN P  +     F     
Sbjct: 572 QNSSGHNNINVNRHSFIVTASDRGIKPLMSETTVMINVVDSNDNPPTFES-PSYFTPVTK 630

Query: 807 CFPVGP-FGRVPAYDA---DVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKL 862
              VG    +V AYD     +  +++Y I  GN++N   L++ TGS+T++  L  +  K+
Sbjct: 631 SVKVGTRLLKVTAYDKKDFGLNSEIEYAISGGNSSNKFRLDKQTGSVTVASSLAADTNKV 690

Query: 863 ATMEVSVTDGVN 874
             +E++ +D  N
Sbjct: 691 YLLEITASDKGN 702



 Score = 44.8 bits (101), Expect = 0.035
 Identities = 64/250 (25%), Positives = 99/250 (39%), Gaps = 34/250 (13%)

Query: 1101 AVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELV 1160
            A+ + R R   +   L  PG        L+LKF T++ SG LL+     E +++  L L 
Sbjct: 1803 ALSQSRKRDVLLERALQGPGRSVLQHSSLELKFRTRSASGTLLHA---QESYNYTTLRL- 1858

Query: 1161 SSEAGRGGGPGLRFSFSLG-GGKSEITVEGNV-GDGSWHTVEIEYFNRTITMILDDCDKV 1218
                 +GG   L++    G  GK E TV   +  DG WHT+ ++    +  + +D     
Sbjct: 1859 -----KGGL--LQYVSDAGVAGKVERTVSDVLLSDGQWHTLLLQRNGSSTVLRIDRSSSK 1911

Query: 1219 LSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKN 1278
            L L    DFG            L +   +PT   H     +G     G         VK 
Sbjct: 1912 LILHNTQDFG------GIDVHTL-SLGGVPTNRKHSDASSSG---FDG-----CYAYVK- 1955

Query: 1279 KDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICD 1338
              + G +  F  +H+ + ++    D     GC    + C S+PC++G  C + W TY C 
Sbjct: 1956 --YNGEMLPFSGEHRTVSISK--TDPSVKIGC-RGPNLCESSPCWDGLMCVNQWYTYQCV 2010

Query: 1339 CKEGHTGKDC 1348
                 T   C
Sbjct: 2011 PPGNCTSNPC 2020



 Score = 43.6 bits (98), Expect = 0.080
 Identities = 56/235 (23%), Positives = 85/235 (36%), Gaps = 31/235 (13%)

Query: 1394 SIQLKSGLLHYSYNGETMYLPMAT-----LSDGAWHRIEIKWLGTDISVTVDYGLRTVLM 1448
            +++LK GLL Y  +         T     LSDG WH + ++  G+   + +D     +++
Sbjct: 1855 TLRLKGGLLQYVSDAGVAGKVERTVSDVLLSDGQWHTLLLQRNGSSTVLRIDRSSSKLIL 1914

Query: 1449 PMLANKIQGQYIGKILIGGLDTTAGLLASDVGFFEGCIQDVR-------IGTAQSLLNRP 1501
                    G  +  + +GG+ T      +    F+GC   V+              ++  
Sbjct: 1915 HN-TQDFGGIDVHTLSLGGVPTNRKHSDASSSGFDGCYAYVKYNGEMLPFSGEHRTVSIS 1973

Query: 1502 TVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPC-GAA 1560
                +V+ GC+    C  S C     CV  W +  C      V P     C   PC    
Sbjct: 1974 KTDPSVKIGCRGPNLCESSPCWDGLMCVNQWYTYQC------VPP---GNCTSNPCQHGG 2024

Query: 1561 RCVPDQTPKGYSCACEPGYT-------LTTSGCIESGKEECPGGWWGGSACGPCA 1608
             CVP     G+SC CE  YT       +   G       +C  G  GG  C P A
Sbjct: 2025 SCVPG-VRGGFSCVCEEFYTGRVCESLVACLGVRCPQGTDCKLGANGGFTCSPSA 2078



 Score = 39.5 bits (88), Expect = 1.3
 Identities = 14/39 (35%), Positives = 18/39 (46%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C   PC+NG  C +L   + C C +G TG  C
Sbjct: 1497 CETDIDECQPTPCHNGGTCHNLVGGFSCTCPDGFTGMAC 1535


>UniRef50_A7SN97 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 850

 Score =  376 bits (924), Expect = e-102
 Identities = 264/798 (33%), Positives = 396/798 (49%), Gaps = 64/798 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V D ND++PVF    Y  +V E +  GT++L + ATD D G+NA V Y++    +  L
Sbjct: 102 IVVGDLNDNNPVFNPTNYSTTVFENSPVGTSLLDVTATDADSGQNAYVTYSVTAGDSHGL 161

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           + V ++    G +    +LDRE    Y + + ATD   P+S   
Sbjct: 162 ---------------FRAVTKVSNH-GTIEVAGNLDREVNDFYNLTITATDGGVPISR-- 203

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV--IAKIKATDADVGANSAIR 188
           ++ A   V I+D NDN P+FS   YT S+ E+ S    PV   + I ATD D+ +N+ +R
Sbjct: 204 TAIAIALVRILDRNDNVPKFSHARYTGSIQEN-SGPGVPVQMASSIMATDRDIESNADVR 262

Query: 189 YAIIGGNTQMQFSIDSLSG----DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
           Y +  G+  +QF+++  +G     VS   +LD+E+  +Y   + A D       +  +++
Sbjct: 263 YRL-NGSDSIQFAVNPRTGVITTRVSPPPSLDHERTTNYTFHVIAADQAGTGHESLAEVV 321

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           I++ D NDN PRF  S  Q ++SE   IG S+ RV A D D G+N  + +++      G 
Sbjct: 322 IHVLDANDNTPRFIPSSIQSTISEAASIGQSVARVTANDPDSGLNGRIFFSINSGS-EGK 380

Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
            +    I    G V  SG LDRE +A Y L V+A DG   PR    T             
Sbjct: 381 FE----IGRSDGVVRVSGSLDREAKAVYVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTP 436

Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLIT 424
            F    + V+++E    G+ +V  TATD D+ +     IT   +   F+I S  G   +T
Sbjct: 437 KFTKPAFNVDVSEGVAVGSVIVNATATDPDQGSNA--AITYSMSYPGFAINSNTGS--VT 492

Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
           + +PLD + ++ Y  TV A D GG      V + I D N+ +P F    Y   V +  P+
Sbjct: 493 ITRPLDRETKQAYSFTVHARDGGGLESNVAVNVEIGDENDNSPQFPTVQYQTDVIDRTPV 552

Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE-- 542
           GT VL V+A D DVG N  +TY++               F+I P TG I T+  LDRE  
Sbjct: 553 GTIVLAVNAEDRDVGNNGHVTYAILI-----------LPFIIVPDTGNINTSSKLDREQQ 601

Query: 543 ---TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
              T+  Y+L ++  D GV   +    + ISV D NDN+P F Q  Y+A ++E+  VGT 
Sbjct: 602 SLYTLVHYVLNLSVTDHGVTQFTSFALLNISVTDFNDNQPQFNQSEYSATVLENMPVGTK 661

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
           V+ V A D D G+N +I Y L   D   G F I+P++G IR  KA++RE+   + +   A
Sbjct: 662 VTMVTARDEDSGINSQIMYSLTGGD---GVFSIEPSTGQIRLQKAINREAKENYHVTITA 718

Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE-NSPIGTTIGEIRAHDPDEGP 718
            D GTP  SS   VH+ + D+ND+PPVF S      +SE N+  G  + ++ A D D   
Sbjct: 719 SDRGTPVLSSDAKVHVHVLDVNDNPPVFTSRVYERTMSEGNAAAGEFVVQVNATDADVER 778

Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLW 775
           N  V Y+I  G     F++    G  + + V    L+ ES +  Y L++ A    + P  
Sbjct: 779 NGHVTYTIMHG-ALGMFTINETTGVIRTQGV----LNRES-KDFYTLIVMARDQGAVPYM 832

Query: 776 NDVRVEILVTDVNDNAPV 793
           +   +++ V D NDN P+
Sbjct: 833 DFGTIDVHVIDKNDNTPI 850



 Score =  334 bits (821), Expect = 2e-89
 Identities = 266/879 (30%), Positives = 402/879 (45%), Gaps = 82/879 (9%)

Query: 21  PVFEMQQYEASVREGASS-GTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXX 79
           PVF    Y A+  EG+S+ G  + T+KATD D G N +V+Y+I  V  +  +P       
Sbjct: 1   PVFTPASYNATFTEGSSTRGVLIATVKATDSDDGANGDVDYSI--VDGNVGDPRSNSD-- 56

Query: 80  XXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVN 139
                     F +D  +G + T  +L+R++   Y + + A D   P     S+T  + + 
Sbjct: 57  ----------FTLDPNTGMIKTARNLERQQTFSYNLTIGAADHGLP---SFSATTRVSIV 103

Query: 140 IIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ 199
           + D NDN P F+   Y+ +V E+  V  +  +  + ATDAD G N+ + Y++  G++   
Sbjct: 104 VGDLNDNNPVFNPTNYSTTVFENSPVGTS--LLDVTATDADSGQNAYVTYSVTAGDSHGL 161

Query: 200 F-SIDSLS--GDVSLVKTLDYEQVRSYRLVIRAQDGGSP-SRSNTTQLLINIRDVNDNAP 255
           F ++  +S  G + +   LD E    Y L I A DGG P SR+     L+ I D NDN P
Sbjct: 162 FRAVTKVSNHGTIEVAGNLDREVNDFYNLTITATDGGVPISRTAIAIALVRILDRNDNVP 221

Query: 256 RF----YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311
           +F    YT   QE+    VP+  +   + A D D   NA++ Y +   D      +   +
Sbjct: 222 KFSHARYTGSIQENSGPGVPVQMA-SSIMATDRDIESNADVRYRLNGSD-----SIQFAV 275

Query: 312 DPRSGWVYT----SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
           +PR+G + T       LD E    Y   V A D       + A               F+
Sbjct: 276 NPRTGVITTRVSPPPSLDHERTTNYTFHVIAADQAGTGHESLAEVVIHVLDANDNTPRFI 335

Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITV 425
           P   +  ++E    G  V  +TA D D   + R+ + I  G + G+F I   +  G++ V
Sbjct: 336 PSSIQSTISEAASIGQSVARVTANDPDSGLNGRIFFSINSG-SEGKFEIGRSD--GVVRV 392

Query: 426 AQPLDFKQERRYVLTVSATDS--GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
           +  LD + +  YVL VSA D     R     V + + D N+  P F    +   V E   
Sbjct: 393 SGSLDREAKAVYVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTPKFTKPAFNVDVSEGVA 452

Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
           +G+ ++  +ATD D G NA ITYS+S              F IN  TG++T  + LDRET
Sbjct: 453 VGSVIVNATATDPDQGSNAAITYSMSY-----------PGFAINSNTGSVTITRPLDRET 501

Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
              Y  TV ARDGG   L     V + + D NDN P F    Y  ++++   VGT V  V
Sbjct: 502 KQAYSFTVHARDGG--GLESNVAVNVEIGDENDNSPQFPTVQYQTDVIDRTPVGTIVLAV 559

Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI--- 660
            A D DVG NG + Y +         F+I P +G I T+  LDRE  + + L    +   
Sbjct: 560 NAEDRDVGNNGHVTYAILIL-----PFIIVPDTGNINTSSKLDREQQSLYTLVHYVLNLS 614

Query: 661 --DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
             D G    +S  +++I + D ND+ P F     +  + EN P+GT +  + A D D G 
Sbjct: 615 VTDHGVTQFTSFALLNISVTDFNDNQPQFNQSEYSATVLENMPVGTKVTMVTARDEDSGI 674

Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLW 775
           N+ + YS+ GGD    FS+E   G  + +      ++ E+ ++ Y + I A+   +P L 
Sbjct: 675 NSQIMYSLTGGD--GVFSIEPSTGQIRLQKA----INREA-KENYHVTITASDRGTPVLS 727

Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADV--TDKLQYRIL 832
           +D +V + V DVNDN PV           +     G F  +V A DADV     + Y I+
Sbjct: 728 SDAKVHVHVLDVNDNPPVFTSRVYERTMSEGNAAAGEFVVQVNATDADVERNGHVTYTIM 787

Query: 833 SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            G    +  +NETTG +     LN       T+ V   D
Sbjct: 788 HG-ALGMFTINETTGVIRTQGVLNRESKDFYTLIVMARD 825



 Score =  194 bits (472), Expect = 4e-47
 Identities = 158/524 (30%), Positives = 237/524 (45%), Gaps = 29/524 (5%)

Query: 366 FMPGQYEVELAEDEPP-GTPVVTLTATDADE--DNRLHYEITGGNT---RGRFSITSQNG 419
           F P  Y     E     G  + T+ ATD+D+  +  + Y I  GN    R     T    
Sbjct: 3   FTPASYNATFTEGSSTRGVLIATVKATDSDDGANGDVDYSIVDGNVGDPRSNSDFTLDPN 62

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477
            G+I  A+ L+ +Q   Y LT+ A D G    S T  V I + D N+  PVF    Y+ +
Sbjct: 63  TGMIKTARNLERQQTFSYNLTIGAADHGLPSFSATTRVSIVVGDLNDNNPVFNPTNYSTT 122

Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
           VFE++P+GT++L V+ATD+D G NA +TYS+++  S+       +  V N  T  +  N 
Sbjct: 123 VFENSPVGTSLLDVTATDADSGQNAYVTYSVTAGDSHGLFRAVTK--VSNHGTIEVAGN- 179

Query: 538 LLDRETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
            LDRE    Y LT+TA DGGVP S +      + ++D NDN P F    YT +I E++  
Sbjct: 180 -LDREVNDFYNLTITATDGGVPISRTAIAIALVRILDRNDNVPKFSHARYTGSIQENSGP 238

Query: 597 GTSV---SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN----KALDRES 649
           G  V   S + ATD D+  N  + Y L+  D  +  F ++P +GVI T      +LD E 
Sbjct: 239 GVPVQMASSIMATDRDIESNADVRYRLNGSDSIQ--FAVNPRTGVITTRVSPPPSLDHER 296

Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
              +    +A D       S   V I + D ND+ P F    +   ISE + IG ++  +
Sbjct: 297 TTNYTFHVIAADQAGTGHESLAEVVIHVLDANDNTPRFIPSSIQSTISEAASIGQSVARV 356

Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
            A+DPD G N  + +SI  G +      E  +      +   +D + ++        I  
Sbjct: 357 TANDPDSGLNGRIFFSINSGSEGK---FEIGRSDGVVRVSGSLDREAKAVYVLNVSAIDG 413

Query: 770 ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVGPFGRVPAYDADVTDKLQ 828
           +  P      V + + DVNDN P  K  +  FN +  +   VG    V A   D      
Sbjct: 414 SYSPREGYGTVTVTLQDVNDNTP--KFTKPAFNVDVSEGVAVGSV-IVNATATDPDQGSN 470

Query: 829 YRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
             I    +     +N  TGS+T++  L+    +  +  V   DG
Sbjct: 471 AAITYSMSYPGFAINSNTGSVTITRPLDRETKQAYSFTVHARDG 514



 Score =  168 bits (409), Expect = 2e-39
 Identities = 134/418 (32%), Positives = 189/418 (45%), Gaps = 17/418 (4%)

Query: 467 PVFENAPYTASVFEDAPI-GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525
           PVF  A Y A+  E +   G  +  V ATDSD G N  + YS+     N      +  F 
Sbjct: 1   PVFTPASYNATFTEGSSTRGVLIATVKATDSDDGANGDVDYSIVD--GNVGDPRSNSDFT 58

Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585
           ++P TG I T + L+R+    Y LT+ A D G+PS S TT V I V D+NDN PVF    
Sbjct: 59  LDPNTGMIKTARNLERQQTFSYNLTIGAADHGLPSFSATTRVSIVVGDLNDNNPVFNPTN 118

Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS--GVIRTNK 643
           Y+  + E++ VGTS+  V ATDAD G N  + Y +   D       +   S  G I    
Sbjct: 119 YSTTVFENSPVGTSLLDVTATDADSGQNAYVTYSVTAGDSHGLFRAVTKVSNHGTIEVAG 178

Query: 644 ALDRESVATHDLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
            LDRE    ++L   A DGG P  +++  I  ++I D ND+ P F     T  I ENS  
Sbjct: 179 NLDREVNDFYNLTITATDGGVPISRTAIAIALVRILDRNDNVPKFSHARYTGSIQENSGP 238

Query: 703 GTTI---GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759
           G  +     I A D D   NA V Y +  G DS  F++  R G     +     LD+E  
Sbjct: 239 GVPVQMASSIMATDRDIESNADVRYRL-NGSDSIQFAVNPRTGVITTRVSPPPSLDHERT 297

Query: 760 RKKYELVIRAASPPLWNDVRVEIL--VTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRV 816
                 VI A      ++   E++  V D NDN P       I +   +   +G    RV
Sbjct: 298 TNYTFHVIAADQAGTGHESLAEVVIHVLDANDNTPRFIP-SSIQSTISEAASIGQSVARV 356

Query: 817 PAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            A D D  +  ++ + I SG+      +  + G + +S  L+     +  + VS  DG
Sbjct: 357 TANDPDSGLNGRIFFSINSGSEGK-FEIGRSDGVVRVSGSLDREAKAVYVLNVSAIDG 413


>UniRef50_Q7Q3K5 Cluster: ENSANGP00000007226; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000007226 - Anopheles gambiae
           str. PEST
          Length = 1645

 Score =  374 bits (920), Expect = e-101
 Identities = 263/814 (32%), Positives = 404/814 (49%), Gaps = 75/814 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + +LD ND+ P+F+   Y  S+ E    GT VL + A+D D+G N+++ Y   L  A+T 
Sbjct: 3   VTILDVNDNPPIFDHSDYIVSLNESVLPGTPVLQVMASDSDLGDNSKITYY--LADAETQ 60

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                              F +D  +G + TR +LDRE VA YT++V A D  SP     
Sbjct: 61  -------------------FTVDPETG-IATRRALDRELVAAYTLVVIARDHGSPPQ--- 97

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           SS+AT+ V + D NDN P+   + + V V ED    +  +IA++ ATD D G N+ ++Y 
Sbjct: 98  SSSATVSVAVEDANDNSPELYPRAFFVPVAED--APEGTLIAQLTATDRDEGENAIVQYE 155

Query: 191 IIGGNT--QMQFSIDSLSGDVSLVKTLDYEQVRSYR------LVIRAQDGGSPSRSNTTQ 242
           ++GG T     F+ID+ +G ++L  +L       +R      L + A DGGSP  +  T 
Sbjct: 156 LVGGPTTDAALFAIDATTGALTLRSSLQKSPKPVHRPGTVLSLEVSATDGGSPPLTTRTT 215

Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
           + + + DVND+ P F  + ++ S+ E++P+      + A DAD G N  ++Y + + +  
Sbjct: 216 VQVTVEDVNDHTPVFDHTSYETSLLESMPVNSRFFALAASDADVGPNGRISYAIVEGN-- 273

Query: 303 GNVDLPITIDPRSGWVYTSGQLDRET---QAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
            + +   +ID R+G++ T    DRE    Q+   L  T +D G                 
Sbjct: 274 -DREEDFSIDSRNGFIRTRRSFDREALGGQSFLALEATVSDNGAVRLRDRVKIKVFITDV 332

Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQ 417
                 F+   Y V+++E    GT +V +   DADE  +  + Y I+ GN   RF+I   
Sbjct: 333 NDNAPVFVRAPYRVQISEGASIGTQLVRVYTHDADEGLNGDVFYYISEGNRAERFAIDDS 392

Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGR---SDTAMVQINITDANNYAPVFENAPY 474
            G+  IT+A+ LD +    Y LTV A D+  +   S +  V I + D N+ AP F     
Sbjct: 393 TGQ--ITLARALDRETTASYRLTVVAHDASKQHRLSASTTVTIEVLDENDDAPEFTQTLS 450

Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
             ++ E  PIGT ++   ATD D+G NAQI +S+       A  +    F I+  +GA+ 
Sbjct: 451 QIAIVETTPIGTELMRFRATDLDLGANAQIAFSI-------AAGNRRDTFHIDALSGALY 503

Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
            ++ LD E    Y L ++A DGG P L+ T    ++V+D NDN P F        I E  
Sbjct: 504 LHRALDYEDTQSYSLNISAADGGNPRLATTILFAVNVIDANDNPPAFPNTAIVRQIREGI 563

Query: 595 LVGTSVSQVGATDADVGLNGRIHYEL---DPKDRE-EGSFVIDPASGVIRTNKALDRESV 650
            + T +  V A D D GLNG++ YE+   DP+D + E  F I+P +GVI T   +DRE++
Sbjct: 564 PLNTPIVTVTAEDPDSGLNGKVRYEIAHQDPQDGDGERHFGINPTTGVIHTLHLIDREAI 623

Query: 651 ATHDLKAVAIDGGTPPQSS-------TVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703
            T+ L  +A D   PP          TVI+ + + D NDSPP F++  L F +SE+  +G
Sbjct: 624 DTYRLTVLATDQAAPPAQRLSAEKLVTVIIRVNVLDKNDSPPKFQNLPLVFSVSEDLAVG 683

Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKK 762
            T+  I A DPD      + Y++  GD    F+LE   G     L+ + D LD E+    
Sbjct: 684 QTVARITATDPD--TLGKLEYALLDGDAPKKFALERETG-----LLKLRDTLDRET-EDS 735

Query: 763 YELVIRAASPPLWNDVRVEILVTDVNDNAPVMKD 796
           Y L +         +  + I +TD NDN PV  +
Sbjct: 736 YRLKVSVTDGIQSTETTITIQITDTNDNPPVFAE 769



 Score =  356 bits (876), Expect = 4e-96
 Identities = 244/776 (31%), Positives = 375/776 (48%), Gaps = 46/776 (5%)

Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195
           ++V I+D NDN P F    Y VS++E + +   PV+ ++ A+D+D+G NS I Y +    
Sbjct: 1   VNVTILDVNDNPPIFDHSDYIVSLNESV-LPGTPVL-QVMASDSDLGDNSKITYYLADAE 58

Query: 196 TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP 255
           TQ  F++D  +G ++  + LD E V +Y LV+ A+D GSP +S++  + + + D NDN+P
Sbjct: 59  TQ--FTVDPETG-IATRRALDRELVAAYTLVVIARDHGSPPQSSSATVSVAVEDANDNSP 115

Query: 256 RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315
             Y   F   V+E+ P G  I ++ A D DEG NA + Y +     T        ID  +
Sbjct: 116 ELYPRAFFVPVAEDAPEGTLIAQLTATDRDEGENAIVQYELVGGPTTDAA--LFAIDATT 173

Query: 316 GWVYTSGQLDRETQAKYQ------LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
           G +     L +  +  ++      L V+ATDGG PP +   T              F   
Sbjct: 174 GALTLRSSLQKSPKPVHRPGTVLSLEVSATDGGSPPLTTRTTVQVTVEDVNDHTPVFDHT 233

Query: 370 QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGR-FSITSQNGRGLITVA 426
            YE  L E  P  +    L A+DAD   + R+ Y I  GN R   FSI S+N  G I   
Sbjct: 234 SYETSLLESMPVNSRFFALAASDADVGPNGRISYAIVEGNDREEDFSIDSRN--GFIRTR 291

Query: 427 QPLDFKQ---ERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFED 481
           +  D +    +    L  + +D+G     D   +++ ITD N+ APVF  APY   + E 
Sbjct: 292 RSFDREALGGQSFLALEATVSDNGAVRLRDRVKIKVFITDVNDNAPVFVRAPYRVQISEG 351

Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
           A IGT ++ V   D+D G+N  + Y +S    N A     ++F I+  TG IT  + LDR
Sbjct: 352 ASIGTQLVRVYTHDADEGLNGDVFYYISE--GNRA-----ERFAIDDSTGQITLARALDR 404

Query: 542 ETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
           ET + Y LTV A D      LS +T V I V+D ND+ P F Q L    I+E   +GT +
Sbjct: 405 ETTASYRLTVVAHDASKQHRLSASTTVTIEVLDENDDAPEFTQTLSQIAIVETTPIGTEL 464

Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
            +  ATD D+G N +I + +   +R + +F ID  SG +  ++ALD E   ++ L   A 
Sbjct: 465 MRFRATDLDLGANAQIAFSIAAGNRRD-TFHIDALSGALYLHRALDYEDTQSYSLNISAA 523

Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
           DGG P  ++T++  + + D ND+PP F +  +   I E  P+ T I  + A DPD G N 
Sbjct: 524 DGGNPRLATTILFAVNVIDANDNPPAFPNTAIVRQIREGIPLNTPIVTVTAEDPDSGLNG 583

Query: 721 VVHYSI-----KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW 775
            V Y I     + GD    F +    G      + ++D +     +   L    A+PP  
Sbjct: 584 KVRYEIAHQDPQDGDGERHFGINPTTG--VIHTLHLIDREAIDTYRLTVLATDQAAPPAQ 641

Query: 776 N-------DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQ 828
                    V + + V D ND+ P  ++  ++F+  +D        R+ A D D   KL+
Sbjct: 642 RLSAEKLVTVIIRVNVLDKNDSPPKFQNLPLVFSVSEDLAVGQTVARITATDPDTLGKLE 701

Query: 829 YRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884
           Y +L G+      L   TG + L   L+        ++VSVTDG+   +  + + +
Sbjct: 702 YALLDGDAPKKFALERETGLLKLRDTLDRETEDSYRLKVSVTDGIQSTETTITIQI 757



 Score =  326 bits (800), Expect = 7e-87
 Identities = 249/810 (30%), Positives = 370/810 (45%), Gaps = 66/810 (8%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           Q+ V D NDH+PVF+   YE S+ E     +    L A+D D+G N  + Y I       
Sbjct: 217 QVTVEDVNDHTPVFDHTSYETSLLESMPVNSRFFALAASDADVGPNGRISYAI------- 269

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
           +   D            ++ F ID R+G + TR S DRE +   + L      +   + R
Sbjct: 270 VEGNDR-----------EEDFSIDSRNGFIRTRRSFDREALGGQSFLALEATVSDNGAVR 318

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           L     I V I D NDN P F    Y V + E  S+     + ++   DAD G N  + Y
Sbjct: 319 LRDRVKIKVFITDVNDNAPVFVRAPYRVQISEGASI--GTQLVRVYTHDADEGLNGDVFY 376

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR-SNTTQLLINIR 248
            I  GN   +F+ID  +G ++L + LD E   SYRL + A D     R S +T + I + 
Sbjct: 377 YISEGNRAERFAIDDSTGQITLARALDRETTASYRLTVVAHDASKQHRLSASTTVTIEVL 436

Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
           D ND+AP F  +L Q ++ E  PIG  ++R +A D D G NA++ +++      GN    
Sbjct: 437 DENDDAPEFTQTLSQIAIVETTPIGTELMRFRATDLDLGANAQIAFSIA----AGNRRDT 492

Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
             ID  SG +Y    LD E    Y L ++A DGG+P  + T                F  
Sbjct: 493 FHIDALSGALYLHRALDYEDTQSYSLNISAADGGNPRLATTILFAVNVIDANDNPPAFPN 552

Query: 369 GQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEIT-----GGNTRGRFSITSQNGRG 421
                ++ E  P  TP+VT+TA D D   + ++ YEI       G+    F I      G
Sbjct: 553 TAIVRQIREGIPLNTPIVTVTAEDPDSGLNGKVRYEIAHQDPQDGDGERHFGINPTT--G 610

Query: 422 LITVAQPLDFKQERRYVLTVSATD---------SGGRSDTAMVQINITDANNYAPVFENA 472
           +I     +D +    Y LTV ATD         S  +  T ++++N+ D N+  P F+N 
Sbjct: 611 VIHTLHLIDREAIDTYRLTVLATDQAAPPAQRLSAEKLVTVIIRVNVLDKNDSPPKFQNL 670

Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
           P   SV ED  +G TV  ++ATD D     ++ Y+L   +  +A     ++F +  +TG 
Sbjct: 671 PLVFSVSEDLAVGQTVARITATDPDT--LGKLEYAL---LDGDA----PKKFALERETGL 721

Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592
           +     LDRET   Y L V+  DG     S  T + I + D NDN PVF +  Y+ +I E
Sbjct: 722 LKLRDTLDRETEDSYRLKVSVTDG---IQSTETTITIQITDTNDNPPVFAEPAYSFDIPE 778

Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS---FVIDPASGVIRTNKALDRES 649
           +A  G  V  + ATD D  +     Y +  +  +  +   F +D +SG I T   LD E 
Sbjct: 779 NAQRGFHVGVIAATDPDNVIPPNNGYVITVRAYDADTPPRFRLDASSGEITTAAVLDCED 838

Query: 650 VATHDLKAVAIDGG-TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
           +  +    +A D   T P+++ V + I ++D+ND+ P F +      + +    G  +  
Sbjct: 839 MPIYHFTLMAQDSSTTEPRATLVNLTIDVQDVNDNSPAFGAPTFHVNVPDRIKPGQFVFG 898

Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLET---RQGSDKAELVTMVDLDYESPRKKYEL 765
            +A D DEG NA + YSI  G    +  L T      +D  E+ T   LD E    +Y L
Sbjct: 899 AKAIDRDEGVNARLLYSIHTGVIEAATELSTPIFEINTDTGEIYTTTRLDRED-IAQYTL 957

Query: 766 VIRAAS---PPLWNDVRVEILVTDVNDNAP 792
           ++ A     P L     V + V D NDN P
Sbjct: 958 IVEAVDQGVPQLTGSATVLVNVLDKNDNPP 987



 Score =  324 bits (796), Expect = 2e-86
 Identities = 275/953 (28%), Positives = 423/953 (44%), Gaps = 57/953 (5%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +NV+D ND+ P F        +REG    T ++T+ A D D G N +V Y  E+   D  
Sbjct: 538  VNVIDANDNPPAFPNTAIVRQIREGIPLNTPIVTVTAEDPDSGLNGKVRY--EIAHQD-- 593

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             P+D               F I+  +G + T   +DRE +  Y + V ATDQA+P + RL
Sbjct: 594  -PQDGDGERH---------FGINPTTGVIHTLHLIDREAIDTYRLTVLATDQAAPPAQRL 643

Query: 131  SS----TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
            S+    T  I VN++D ND+ P+F       SV ED++V     +A+I ATD D      
Sbjct: 644  SAEKLVTVIIRVNVLDKNDSPPKFQNLPLVFSVSEDLAV--GQTVARITATDPDTLGK-- 699

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            + YA++ G+   +F+++  +G + L  TLD E   SYRL +   DG    +S  T + I 
Sbjct: 700  LEYALLDGDAPKKFALERETGLLKLRDTLDRETEDSYRLKVSVTDG---IQSTETTITIQ 756

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            I D NDN P F    +   + EN   G+ +  + A D D  +     Y +T + Y  +  
Sbjct: 757  ITDTNDNPPVFAEPAYSFDIPENAQRGFHVGVIAATDPDNVIPPNNGYVITVRAYDADTP 816

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSATATXXXXXXXXXXXXXX 365
                +D  SG + T+  LD E    Y   + A D     PR+                  
Sbjct: 817  PRFRLDASSGEITTAAVLDCEDMPIYHFTLMAQDSSTTEPRATLVNLTIDVQDVNDNSPA 876

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITS-----QN 418
            F    + V + +   PG  V    A D DE  + RL Y I  G       +++       
Sbjct: 877  FGAPTFHVNVPDRIKPGQFVFGAKAIDRDEGVNARLLYSIHTGVIEAATELSTPIFEINT 936

Query: 419  GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTA 476
              G I     LD +   +Y L V A D G    + +A V +N+ D N+  P F       
Sbjct: 937  DTGEIYTTTRLDREDIAQYTLIVEAVDQGVPQLTGSATVLVNVLDKNDNPPKFTRLFSDE 996

Query: 477  SVFEDAPIG---TTVLVVSATDSDVGINA----QITYSLSSEISNEAVAHHDQQFVINPQ 529
             + + A +     T   ++ T  D   NA       YS +     ++V   +  F++N  
Sbjct: 997  YILKVAAVDGAWRTETPLTITIQDQNDNAPEFEHSYYSFNFRELQKSVTFRND-FMVNSV 1055

Query: 530  TGAITTNKLLDRETMSGYLLTVTARDGGV-PSLSDT-TDVEISVVDVNDNEPVFKQQLYT 587
            TGA++    LD + +  Y L +TA D G  P  S     + IS+ D ND  P F++ LY 
Sbjct: 1056 TGAVSIRNPLDYDLIQVYQLNITAEDLGYKPKRSIAMAQIIISIQDGND-PPEFQRDLYE 1114

Query: 588  ANIMEDALVGTSVSQVGATDADVG-LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646
            A++ E   +GT V  V A D DV   N +  + +   + +  SF IDP SG I T + LD
Sbjct: 1115 ASVSEGDPIGTKVIVVKAVDKDVRPQNNQFSFSIIGGNNDH-SFKIDPQSGQIETARKLD 1173

Query: 647  RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706
            RE+V TH L   AID GTPPQ+ T +V I + DIND+ P F+       + EN P  T +
Sbjct: 1174 RETVPTHKLLLGAIDTGTPPQTGTTVVRITVTDINDNGPTFDPKDTIGAVLENEPPNTVV 1233

Query: 707  GEIRAHDPDEGPN-AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPRKKYE 764
              + A DPD  PN A   Y + GG   + F+LE   G     L T+  LD E +P+ +  
Sbjct: 1234 MTLAATDPDLPPNGAPFTYQLVGGRHKSLFTLERHSG----VLKTVRSLDREQTPQLELL 1289

Query: 765  LVIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV 823
            +V+     P       + + V D ND+    ++  ++   +++    G    V   D DV
Sbjct: 1290 VVVEDNGKPRKRTQHTITVNVLDQNDSPSTPRNVHVLVYAFREGPLHGDIASVHPNDPDV 1349

Query: 824  TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLA-TMEVSVTDGVN-EIKAMMQ 881
            T   + ++L+  N   +     +    L       +P    T  VS  DG + ++ + + 
Sbjct: 1350 TGDYRCKLLTDTNKQPVTTFTISSGCQLRLTNANRIPTSGHTFLVSGNDGKHPDVTSTVS 1409

Query: 882  LSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIF 934
            +         +  SITVRL ++++  FL+     F+D + A +    + I  F
Sbjct: 1410 VEFLHFDNATVDQSITVRLENISSANFLANYYRNFVDIVKASLEPADDLILCF 1462



 Score =  314 bits (770), Expect = 3e-83
 Identities = 249/879 (28%), Positives = 405/879 (46%), Gaps = 63/879 (7%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ + D ND++PVF    Y   + EGAS GT ++ +   D D G N +V Y I       
Sbjct: 326  KVFITDVNDNAPVFVRAPYRVQISEGASIGTQLVRVYTHDADEGLNGDVFYYIS------ 379

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                              + F ID  +G +    +LDRE  A Y + V A D +     R
Sbjct: 380  -------------EGNRAERFAIDDSTGQITLARALDRETTASYRLTVVAHDASK--QHR 424

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            LS++ T+ + ++D+ND+ P+F++    +++ E   +     + + +ATD D+GAN+ I +
Sbjct: 425  LSASTTVTIEVLDENDDAPEFTQTLSQIAIVETTPIGTE--LMRFRATDLDLGANAQIAF 482

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            +I  GN +  F ID+LSG + L + LDYE  +SY L I A DGG+P  + T    +N+ D
Sbjct: 483  SIAAGNRRDTFHIDALSGALYLHRALDYEDTQSYSLNISAADGGNPRLATTILFAVNVID 542

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD-YTGNVDLP 308
             NDN P F  +     + E +P+   IV V A D D G+N ++ Y +  +D   G+ +  
Sbjct: 543  ANDNPPAFPNTAIVRQIREGIPLNTPIVTVTAEDPDSGLNGKVRYEIAHQDPQDGDGERH 602

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXXXXF 366
              I+P +G ++T   +DRE    Y+L V ATD   PP  R +                  
Sbjct: 603  FGINPTTGVIHTLHLIDREAIDTYRLTVLATDQAAPPAQRLSAEKLVTVIIRVNVLDKND 662

Query: 367  MPGQYE-----VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421
             P +++       ++ED   G  V  +TATD D   +L Y +  G+   +F++  +   G
Sbjct: 663  SPPKFQNLPLVFSVSEDLAVGQTVARITATDPDTLGKLEYALLDGDAPKKFALERET--G 720

Query: 422  LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
            L+ +   LD + E  Y L VS TD G +S    + I ITD N+  PVF    Y+  + E+
Sbjct: 721  LLKLRDTLDRETEDSYRLKVSVTD-GIQSTETTITIQITDTNDNPPVFAEPAYSFDIPEN 779

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
            A  G  V V++ATD D  I     Y ++    +   A    +F ++  +G ITT  +LD 
Sbjct: 780  AQRGFHVGVIAATDPDNVIPPNNGYVITVRAYD---ADTPPRFRLDASSGEITTAAVLDC 836

Query: 542  ETMSGYLLTVTARDGGVPSLSDT-TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
            E M  Y  T+ A+D        T  ++ I V DVNDN P F    +  N+ +    G  V
Sbjct: 837  EDMPIYHFTLMAQDSSTTEPRATLVNLTIDVQDVNDNSPAFGAPTFHVNVPDRIKPGQFV 896

Query: 601  SQVGATDADVGLNGRIHYELDPKDREEGS------FVIDPASGVIRTNKALDRESVATHD 654
                A D D G+N R+ Y +     E  +      F I+  +G I T   LDRE +A + 
Sbjct: 897  FGAKAIDRDEGVNARLLYSIHTGVIEAATELSTPIFEINTDTGEIYTTTRLDREDIAQYT 956

Query: 655  LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE----------NSPIGT 704
            L   A+D G P  + +  V + + D ND+PP F       YI +           +P+  
Sbjct: 957  LIVEAVDQGVPQLTGSATVLVNVLDKNDNPPKFTRLFSDEYILKVAAVDGAWRTETPLTI 1016

Query: 705  TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764
            TI +   + P E  ++   ++ +    S +F  +    S    +     LDY+   + Y+
Sbjct: 1017 TIQDQNDNAP-EFEHSYYSFNFRELQKSVTFRNDFMVNSVTGAVSIRNPLDYDL-IQVYQ 1074

Query: 765  LVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYD 820
            L I A      P  +    +I+++  + N P      +   +  +  P+G     V A D
Sbjct: 1075 LNITAEDLGYKPKRSIAMAQIIISIQDGNDPPEFQRDLYEASVSEGDPIGTKVIVVKAVD 1134

Query: 821  ADV---TDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
             DV    ++  + I+ GNN +   ++  +G +  + +L+
Sbjct: 1135 KDVRPQNNQFSFSIIGGNNDHSFKIDPQSGQIETARKLD 1173



 Score =  207 bits (506), Expect = 3e-51
 Identities = 174/607 (28%), Positives = 279/607 (45%), Gaps = 52/607 (8%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            ++  I+V D ND+SP F    +  +V +    G  V   KA D+D G NA + Y+I    
Sbjct: 861  VNLTIDVQDVNDNSPAFGAPTFHVNVPDRIKPGQFVFGAKAIDRDEGVNARLLYSIHTGV 920

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
             +                    +F I+  +G + T   LDRE +A+YT++V+A DQ  P 
Sbjct: 921  IE------------AATELSTPIFEINTDTGEIYTTTRLDREDIAQYTLIVEAVDQGVP- 967

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFS-----EKTYTVSVDEDISVTDNPVIAKIKATDADV 181
              +L+ +AT+ VN++D NDN P+F+     E    V+  +    T+ P+   I+  + + 
Sbjct: 968  --QLTGSATVLVNVLDKNDNPPKFTRLFSDEYILKVAAVDGAWRTETPLTITIQDQNDNA 1025

Query: 182  GANSAIRYAIIGGNTQM------QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD-GGS 234
                   Y+      Q        F ++S++G VS+   LDY+ ++ Y+L I A+D G  
Sbjct: 1026 PEFEHSYYSFNFRELQKSVTFRNDFMVNSVTGAVSIRNPLDYDLIQVYQLNITAEDLGYK 1085

Query: 235  PSRS-NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAEL 292
            P RS    Q++I+I+D ND  P F   L++ SVSE  PIG  ++ V+A D D    N + 
Sbjct: 1086 PKRSIAMAQIIISIQDGND-PPEFQRDLYEASVSEGDPIGTKVIVVKAVDKDVRPQNNQF 1144

Query: 293  TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352
            ++++      GN D    IDP+SG + T+ +LDRET   ++LL+ A D G PP++ T   
Sbjct: 1145 SFSIIG----GNNDHSFKIDPQSGQIETARKLDRETVPTHKLLLGAIDTGTPPQTGTTVV 1200

Query: 353  XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTR 409
                         F P      + E+EPP T V+TL ATD D         Y++ GG  +
Sbjct: 1201 RITVTDINDNGPTFDPKDTIGAVLENEPPNTVVMTLAATDPDLPPNGAPFTYQLVGGRHK 1260

Query: 410  GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG-GRSDTA-MVQINITDANNYAP 467
              F  T +   G++   + LD +Q  +  L V   D+G  R  T   + +N+ D N+   
Sbjct: 1261 SLF--TLERHSGVLKTVRSLDREQTPQLELLVVVEDNGKPRKRTQHTITVNVLDQNDSPS 1318

Query: 468  VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527
               N       F + P+   +  V   D DV         L ++ + + V      F I+
Sbjct: 1319 TPRNVHVLVYAFREGPLHGDIASVHPNDPDV--TGDYRCKLLTDTNKQPVT----TFTIS 1372

Query: 528  PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD---VNDNEPVFKQQ 584
                   TN   +R   SG+   V+  DG  P ++ T  VE    D   V+ +  V  + 
Sbjct: 1373 SGCQLRLTN--ANRIPTSGHTFLVSGNDGKHPDVTSTVSVEFLHFDNATVDQSITVRLEN 1430

Query: 585  LYTANIM 591
            + +AN +
Sbjct: 1431 ISSANFL 1437


>UniRef50_Q4S3T8 Cluster: Chromosome 20 SCAF14744, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 20 SCAF14744, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 2413

 Score =  373 bits (918), Expect = e-101
 Identities = 264/795 (33%), Positives = 388/795 (48%), Gaps = 46/795 (5%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +I VLD ND+SPVF       S +E ASSG  V+   ATD DIG N     T  +V    
Sbjct: 107 RIVVLDINDNSPVFPDASIVVSFKEDASSGRQVILDTATDTDIGSNGVDHTTYRIVKG-- 164

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            N +             +  F        L++   LDRE    Y +L++  D+  P   +
Sbjct: 165 -NEQRKFRLDITVNPSGEGAFL------HLVSTGGLDREVTPFYQLLIEVEDKGEP---K 214

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
                 ++V I D NDN P F    Y  SV ED +V  +  I ++ A+D D  AN+ IRY
Sbjct: 215 TFGYLQVNVTIQDINDNPPSFERDLYQASVLEDAAVGSS--ILQVTASDGDEAANAEIRY 272

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            +   + +  F ID  +G + + + LDYE  R Y L I A D G PS S   +  I + D
Sbjct: 273 FL---DEETPFQIDPKTGTIIIKEGLDYESRREYSLTIHAVDNGVPSLSGRAEATIKLLD 329

Query: 250 VNDNAP----RFY--TSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYT 302
           VNDN P    R++  TS F  SV EN  +G  +  +   D+D    N  ++ ++   +  
Sbjct: 330 VNDNDPVVKFRYFPTTSKF-ASVDENAQVGTVVALLTVSDSDSSAANGNISVSILGGNEQ 388

Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSATATXXXXXXXXXX 361
            + ++  +  P    +  +  LDRE  + Y L V+ +D G P  RS+ A+          
Sbjct: 389 RHFEVHTSPVPNLSLIKVASVLDRERISSYNLTVSVSDNGKPVARSSFASLVIFVNDIND 448

Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419
               F   +Y V+++ED P G+ +  ++ATD D  ++  L Y +  GN  G FSI S+N 
Sbjct: 449 HPPIFQETEYRVDISEDIPKGSYIKGVSATDGDSGQNANLRYSLVSGNALGWFSI-SENS 507

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477
            GL+T A  LD +     VL +SA D G   R     + INITD N+  P F  + +  S
Sbjct: 508 -GLVTSAALLDREATSEVVLNISAKDQGLQPRISYTKLIINITDVNDQVPTFTQSTFHVS 566

Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
           + E AP GT +LV+SATD D+G N  + +S  +E    A      +F ++P +G ++T  
Sbjct: 567 LAEHAPAGTQLLVLSATDGDLGPNGTMRFSFDAETPAAA----QGRFRLDPLSGRLSTAV 622

Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
            LDRE  + YLL V   DGG P L     V +++ DVNDN PVF    Y AN+ E+   G
Sbjct: 623 ELDREEQASYLLHVQVTDGGSPPLRSAGKVNVTLRDVNDNRPVFYPLQYFANVKENEPSG 682

Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
           + V+ V ATD D+G NG + Y +   D    +F I+  +G I T   LDRE   T+ L+ 
Sbjct: 683 SYVTTVSATDPDLGRNGTVKYMITAGD--AATFHINGNTGKISTLVPLDREEKTTYQLQV 740

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
            A DG      +  IV + + D  D+PPVF     +F + EN  +GT +G + A   D  
Sbjct: 741 TAADGSGLRSHTPAIVTVSVLDTQDNPPVFSQKGYSFVMFENVGVGTVVGTVSATTVDLN 800

Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND 777
            N  V Y I  GD    F++     +   ++     +D E  +  ++L + A +  +  +
Sbjct: 801 TN--VSYLITSGDQRGLFAV-----NSAGQITASSPIDREE-QSFHQLKVVARAGQITGE 852

Query: 778 VRVEILVTDVNDNAP 792
           V V I V D+NDNAP
Sbjct: 853 VSVNITVKDLNDNAP 867



 Score =  355 bits (873), Expect = 1e-95
 Identities = 263/858 (30%), Positives = 408/858 (47%), Gaps = 56/858 (6%)

Query: 11   INVLDCNDHSPVFEMQQYE-----ASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELV 65
            I +LD ND+ PV + + +      ASV E A  GT V  L  +D D    A    ++ ++
Sbjct: 325  IKLLDVNDNDPVVKFRYFPTTSKFASVDENAQVGTVVALLTVSDSD-SSAANGNISVSIL 383

Query: 66   TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125
              +     +           ++               + LDRE+++ Y + V  +D   P
Sbjct: 384  GGNEQRHFEVHTSPVPNLSLIK-------------VASVLDRERISSYNLTVSVSDNGKP 430

Query: 126  VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
            V+   SS A++ + + D ND+ P F E  Y V + EDI       I  + ATD D G N+
Sbjct: 431  VAR--SSFASLVIFVNDINDHPPIFQETEYRVDISEDIP--KGSYIKGVSATDGDSGQNA 486

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
             +RY+++ GN    FSI   SG V+    LD E      L I A+D G   R + T+L+I
Sbjct: 487  NLRYSLVSGNALGWFSISENSGLVTSAALLDREATSEVVLNISAKDQGLQPRISYTKLII 546

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
            NI DVND  P F  S F  S++E+ P G  ++ + A D D G N  + ++  D +     
Sbjct: 547  NITDVNDQVPTFTQSTFHVSLAEHAPAGTQLLVLSATDGDLGPNGTMRFSF-DAETPAAA 605

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
                 +DP SG + T+ +LDRE QA Y L V  TDGG PP  +                 
Sbjct: 606  QGRFRLDPLSGRLSTAVELDREEQASYLLHVQVTDGGSPPLRSAGKVNVTLRDVNDNRPV 665

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLI 423
            F P QY   + E+EP G+ V T++ATD D   +  + Y IT G+    F I    G+  I
Sbjct: 666  FYPLQYFANVKENEPSGSYVTTVSATDPDLGRNGTVKYMITAGDA-ATFHINGNTGK--I 722

Query: 424  TVAQPLDFKQERRYVLTVSATD-SGGRSDT-AMVQINITDANNYAPVFENAPYTASVFED 481
            +   PLD +++  Y L V+A D SG RS T A+V +++ D  +  PVF    Y+  +FE+
Sbjct: 723  STLVPLDREEKTTYQLQVTAADGSGLRSHTPAIVTVSVLDTQDNPPVFSQKGYSFVMFEN 782

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
              +GT V  VSAT  D  +N  ++Y ++S             F +N   G IT +  +DR
Sbjct: 783  VGVGTVVGTVSATTVD--LNTNVSYLITS-------GDQRGLFAVN-SAGQITASSPIDR 832

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
            E  S + L V AR G    ++    V I+V D+NDN P F   +   + +E+   G ++ 
Sbjct: 833  EEQSFHQLKVVARAG---QITGEVSVNITVKDLNDNAPRFIHAVEHVSAVENWSTGHTIF 889

Query: 602  QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
            Q  A+D D G NG + Y L  K    G F I    G+I     L+  + ++++++ +A D
Sbjct: 890  QAKASDPDEGANGVVVYSL--KQNPRGLFHIHEKHGLITLTGPLE-VTASSYEVEVIAED 946

Query: 662  GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
             G P  +S++++ + + D+ND+ PVF+       I E+ P+ +   ++ A D D G N  
Sbjct: 947  MGVPKHTSSLVLIVSVYDVNDNSPVFDQLSYEVLIPESEPVNSRFFKVEATDKDSGFNGE 1006

Query: 722  VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDV 778
            + Y I GG+  + F +         +L    +LD E  +++Y LV+ A   A  PL   V
Sbjct: 1007 IVYDIAGGNTGDVFGI-----FPDGQLYIKAELDREI-QERYNLVLVARDRAVEPLSASV 1060

Query: 779  RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNAN 838
             V +++ DVNDN P+      +F+  ++       GRV A D D     + R        
Sbjct: 1061 NVSVILDDVNDNRPLFNSTNYVFHFEEEQQRGSLVGRVFAEDKDFGPNSEVRYTFEMPQP 1120

Query: 839  LILLNETTGSMTLSPQLN 856
               LN  TG ++ + Q +
Sbjct: 1121 NFELNAITGELSSTAQFD 1138



 Score =  354 bits (871), Expect = 2e-95
 Identities = 258/812 (31%), Positives = 391/812 (48%), Gaps = 57/812 (7%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           +F I+G SG + T A +DRE +    + V        +S + +    + + ++D NDN P
Sbjct: 65  LFSINGSSGVISTSAVIDREALQSDVINVVV------LSSQPTYPTEVRIVVLDINDNSP 118

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA--IRYAIIGGNTQMQFSID--- 203
            F + +  VS  ED S +   VI    ATD D+G+N      Y I+ GN Q +F +D   
Sbjct: 119 VFPDASIVVSFKEDAS-SGRQVILDT-ATDTDIGSNGVDHTTYRIVKGNEQRKFRLDITV 176

Query: 204 SLSGD---VSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY 258
           + SG+   + LV T  LD E    Y+L+I  +D G P      Q+ + I+D+NDN P F 
Sbjct: 177 NPSGEGAFLHLVSTGGLDREVTPFYQLLIEVEDKGEPKTFGYLQVNVTIQDINDNPPSFE 236

Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV 318
             L+Q SV E+  +G SI++V A D DE  NAE+ Y + +       + P  IDP++G +
Sbjct: 237 RDLYQASVLEDAAVGSSILQVTASDGDEAANAEIRYFLDE-------ETPFQIDPKTGTI 289

Query: 319 YTSGQLDRETQAKYQLLVTATDGGDPPRS----ATATXXXXXXXXXXXXXXFMPGQYE-V 373
                LD E++ +Y L + A D G P  S    AT                + P   +  
Sbjct: 290 IIKEGLDYESRREYSLTIHAVDNGVPSLSGRAEATIKLLDVNDNDPVVKFRYFPTTSKFA 349

Query: 374 ELAEDEPPGTPVVTLTATDADE---DNRLHYEITGGNTRGRFSITSQ--NGRGLITVAQP 428
            + E+   GT V  LT +D+D    +  +   I GGN +  F + +       LI VA  
Sbjct: 350 SVDENAQVGTVVALLTVSDSDSSAANGNISVSILGGNEQRHFEVHTSPVPNLSLIKVASV 409

Query: 429 LDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
           LD ++   Y LTVS +D+G    RS  A + I + D N++ P+F+   Y   + ED P G
Sbjct: 410 LDRERISSYNLTVSVSDNGKPVARSSFASLVIFVNDINDHPPIFQETEYRVDISEDIPKG 469

Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
           + +  VSATD D G NA + YSL   +S  A+      F I+  +G +T+  LLDRE  S
Sbjct: 470 SYIKGVSATDGDSGQNANLRYSL---VSGNALG----WFSISENSGLVTSAALLDREATS 522

Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
             +L ++A+D G+      T + I++ DVND  P F Q  +  ++ E A  GT +  + A
Sbjct: 523 EVVLNISAKDQGLQPRISYTKLIINITDVNDQVPTFTQSTFHVSLAEHAPAGTQLLVLSA 582

Query: 606 TDADVGLNGRIHYELDPKD--REEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
           TD D+G NG + +  D +     +G F +DP SG + T   LDRE  A++ L     DGG
Sbjct: 583 TDGDLGPNGTMRFSFDAETPAAAQGRFRLDPLSGRLSTAVELDREEQASYLLHVQVTDGG 642

Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
           +PP  S   V++ + D+ND+ PVF        + EN P G+ +  + A DPD G N  V 
Sbjct: 643 SPPLRSAGKVNVTLRDVNDNRPVFYPLQYFANVKENEPSGSYVTTVSATDPDLGRNGTVK 702

Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP---LWNDVRV 780
           Y I  G D+ +F +    G    ++ T+V LD E  +  Y+L + AA            V
Sbjct: 703 YMITAG-DAATFHINGNTG----KISTLVPLDREE-KTTYQLQVTAADGSGLRSHTPAIV 756

Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLI 840
            + V D  DN PV       F  +++       G V A   D+   + Y I SG+   L 
Sbjct: 757 TVSVLDTQDNPPVFSQKGYSFVMFENVGVGTVVGTVSATTVDLNTNVSYLITSGDQRGLF 816

Query: 841 LLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            +N + G +T S  ++        ++V    G
Sbjct: 817 AVN-SAGQITASSPIDREEQSFHQLKVVARAG 847



 Score =  350 bits (860), Expect = 4e-94
 Identities = 269/890 (30%), Positives = 413/890 (46%), Gaps = 57/890 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D NDH P+F+  +Y   + E    G+ +  + ATD D G+NA + Y+  LV+ + L
Sbjct: 441  IFVNDINDHPPIFQETEYRVDISEDIPKGSYIKGVSATDGDSGQNANLRYS--LVSGNAL 498

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F I   SG + + A LDRE  +   + + A DQ   +  R+
Sbjct: 499  G-----------------WFSISENSGLVTSAALLDREATSEVVLNISAKDQG--LQPRI 539

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S T  I +NI D ND  P F++ T+ VS+ E        ++  + ATD D+G N  +R++
Sbjct: 540  SYTKLI-INITDVNDQVPTFTQSTFHVSLAEHAPAGTQLLV--LSATDGDLGPNGTMRFS 596

Query: 191  IIGGN---TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
                     Q +F +D LSG +S    LD E+  SY L ++  DGGSP   +  ++ + +
Sbjct: 597  FDAETPAAAQGRFRLDPLSGRLSTAVELDREEQASYLLHVQVTDGGSPPLRSAGKVNVTL 656

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            RDVNDN P FY   +  +V EN P G  +  V A D D G N  + Y +T  D       
Sbjct: 657  RDVNDNRPVFYPLQYFANVKENEPSGSYVTTVSATDPDLGRNGTVKYMITAGDAA----- 711

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
               I+  +G + T   LDRE +  YQL VTA DG        A               F 
Sbjct: 712  TFHINGNTGKISTLVPLDREEKTTYQLQVTAADGSGLRSHTPAIVTVSVLDTQDNPPVFS 771

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
               Y   + E+   GT V T++AT  D +  + Y IT G+ RG F++   N  G IT + 
Sbjct: 772  QKGYSFVMFENVGVGTVVGTVSATTVDLNTNVSYLITSGDQRGLFAV---NSAGQITASS 828

Query: 428  PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
            P+D +++  + L V A  +G  +    V I + D N+ AP F +A    S  E+   G T
Sbjct: 829  PIDREEQSFHQLKVVAR-AGQITGEVSVNITVKDLNDNAPRFIHAVEHVSAVENWSTGHT 887

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
            +    A+D D G N  + YSL     N     H     I+ + G IT    L+  T S Y
Sbjct: 888  IFQAKASDPDEGANGVVVYSLKQ---NPRGLFH-----IHEKHGLITLTGPLE-VTASSY 938

Query: 548  LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
             + V A D GVP  + +  + +SV DVNDN PVF Q  Y   I E   V +   +V ATD
Sbjct: 939  EVEVIAEDMGVPKHTSSLVLIVSVYDVNDNSPVFDQLSYEVLIPESEPVNSRFFKVEATD 998

Query: 608  ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
             D G NG I Y++   +  +  F I P  G +     LDRE    ++L  VA D    P 
Sbjct: 999  KDSGFNGEIVYDIAGGNTGD-VFGIFP-DGQLYIKAELDREIQERYNLVLVARDRAVEPL 1056

Query: 668  SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
            S++V V + ++D+ND+ P+F S    F+  E    G+ +G + A D D GPN+ V Y+ +
Sbjct: 1057 SASVNVSVILDDVNDNRPLFNSTNYVFHFEEEQQRGSLVGRVFAEDKDFGPNSEVRYTFE 1116

Query: 728  GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP----PLWNDVRVEIL 783
                +   +  T + S  A+      L  +     +  V+ ++      PL +  +V++ 
Sbjct: 1117 MPQPNFELNAITGELSSTAQF-DRESLMRQRGAAVFSFVVVSSDQGLPRPLKDQAKVQVY 1175

Query: 784  VTDVNDNAPVMKDFQIIFNNYKDCFP-VGPFGRVPAYDADVTDK--LQYRILSGNNANLI 840
            + D+NDN P      +   +  +  P V    RV A D D      +QY +  GN     
Sbjct: 1176 IQDINDNQPKFTK-DVYQASVSESAPNVTQLLRVSASDVDENKNGLVQYHVAEGNEEGQF 1234

Query: 841  LLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE-IKAMMQLSVRLITE 889
            +++ ++G +TL  +L+       ++++   DG  E + +   LS+ ++ E
Sbjct: 1235 MIDSSSGQITLVGKLDYETTSSYSLKIIAVDGGAEPLSSSCMLSISVLDE 1284



 Score =  344 bits (846), Expect = 2e-92
 Identities = 281/902 (31%), Positives = 433/902 (48%), Gaps = 84/902 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + + D ND+ P FE   Y+ASV E A+ G+++L + A+D D   NAE+ Y ++  T    
Sbjct: 223  VTIQDINDNPPSFERDLYQASVLEDAAVGSSILQVTASDGDEAANAEIRYFLDEETP--- 279

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F+ID ++G ++ +  LD E    Y++ + A D   P    L
Sbjct: 280  -------------------FQIDPKTGTIIIKEGLDYESRREYSLTIHAVDNGVP---SL 317

Query: 131  SSTATIHVNIIDDNDNYP-----QFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGAN 184
            S  A   + ++D NDN P      F   +   SVDE+  V    V+A +  +D+D   AN
Sbjct: 318  SGRAEATIKLLDVNDNDPVVKFRYFPTTSKFASVDENAQV--GTVVALLTVSDSDSSAAN 375

Query: 185  SAIRYAIIGGNTQMQFSI-DSLSGDVSLVK---TLDYEQVRSYRLVIRAQDGGSP-SRSN 239
              I  +I+GGN Q  F +  S   ++SL+K    LD E++ SY L +   D G P +RS+
Sbjct: 376  GNISVSILGGNEQRHFEVHTSPVPNLSLIKVASVLDRERISSYNLTVSVSDNGKPVARSS 435

Query: 240  TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
               L+I + D+ND+ P F  + ++  +SE++P G  I  V A D D G NA L Y++   
Sbjct: 436  FASLVIFVNDINDHPPIFQETEYRVDISEDIPKGSYIKGVSATDGDSGQNANLRYSLV-- 493

Query: 300  DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
              +GN     +I   SG V ++  LDRE  ++  L ++A D G  PR +           
Sbjct: 494  --SGNALGWFSISENSGLVTSAALLDREATSEVVLNISAKDQGLQPRISYTKLIINITDV 551

Query: 360  XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEI---TGGNTRGRFSI 414
                  F    + V LAE  P GT ++ L+ATD D   +  + +     T    +GRF +
Sbjct: 552  NDQVPTFTQSTFHVSLAEHAPAGTQLLVLSATDGDLGPNGTMRFSFDAETPAAAQGRFRL 611

Query: 415  TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENA 472
               +GR  ++ A  LD +++  Y+L V  TD G     +  ++N+T  D N+  PVF   
Sbjct: 612  DPLSGR--LSTAVELDREEQASYLLHVQVTDGGSPPLRSAGKVNVTLRDVNDNRPVFYPL 669

Query: 473  PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
             Y A+V E+ P G+ V  VSATD D+G N  + Y ++   + +A   H     IN  TG 
Sbjct: 670  QYFANVKENEPSGSYVTTVSATDPDLGRNGTVKYMIT---AGDAATFH-----INGNTGK 721

Query: 533  ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592
            I+T   LDRE  + Y L VTA DG          V +SV+D  DN PVF Q+ Y+  + E
Sbjct: 722  ISTLVPLDREEKTTYQLQVTAADGSGLRSHTPAIVTVSVLDTQDNPPVFSQKGYSFVMFE 781

Query: 593  DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652
            +  VGT V  V AT  D  LN  + Y +   D + G F ++ A G I  +  +DRE  + 
Sbjct: 782  NVGVGTVVGTVSATTVD--LNTNVSYLITSGD-QRGLFAVNSA-GQITASSPIDREEQSF 837

Query: 653  HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
            H LK VA  G     +  V V+I ++D+ND+ P F          EN   G TI + +A 
Sbjct: 838  HQLKVVARAGQI---TGEVSVNITVKDLNDNAPRFIHAVEHVSAVENWSTGHTIFQAKAS 894

Query: 713  DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRAAS 771
            DPDEG N VV YS+K  +    F +  + G     L+T+   L+  +   + E++     
Sbjct: 895  DPDEGANGVVVYSLK-QNPRGLFHIHEKHG-----LITLTGPLEVTASSYEVEVIAEDMG 948

Query: 772  PPLWNDVRVEIL-VTDVNDNAPVMK--DFQIIFNNYKDCFPVGP-FGRVPAYDAD--VTD 825
             P      V I+ V DVNDN+PV     ++++     +  PV   F +V A D D     
Sbjct: 949  VPKHTSSLVLIVSVYDVNDNSPVFDQLSYEVLI---PESEPVNSRFFKVEATDKDSGFNG 1005

Query: 826  KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSV 884
            ++ Y I  GN  ++  +    G + +  +L+  + +   + +   D  V  + A + +SV
Sbjct: 1006 EIVYDIAGGNTGDVFGI-FPDGQLYIKAELDREIQERYNLVLVARDRAVEPLSASVNVSV 1064

Query: 885  RL 886
             L
Sbjct: 1065 IL 1066



 Score =  343 bits (844), Expect = 3e-92
 Identities = 258/879 (29%), Positives = 426/879 (48%), Gaps = 74/879 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + + D ND+ PVF   QY A+V+E   SG+ V T+ ATD D+G+N  V+Y   ++TA   
Sbjct: 654  VTLRDVNDNRPVFYPLQYFANVKENEPSGSYVTTVSATDPDLGRNGTVKY---MITAG-- 708

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
               DA              F I+G +G + T   LDRE+   Y + V A D +     R 
Sbjct: 709  ---DAAT------------FHINGNTGKISTLVPLDREEKTTYQLQVTAADGSGL---RS 750

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             + A + V+++D  DN P FS+K Y+  + E++ V    V+  + AT  D+  N  + Y 
Sbjct: 751  HTPAIVTVSVLDTQDNPPVFSQKGYSFVMFENVGV--GTVVGTVSATTVDLNTN--VSYL 806

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I  G+ +  F+++S +G ++    +D E+   ++L + A+ G     +    + I ++D+
Sbjct: 807  ITSGDQRGLFAVNS-AGQITASSPIDREEQSFHQLKVVARAG---QITGEVSVNITVKDL 862

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDNAPRF  ++   S  EN   G++I + +A D DEG N  + Y++       N      
Sbjct: 863  NDNAPRFIHAVEHVSAVENWSTGHTIFQAKASDPDEGANGVVVYSLKQ-----NPRGLFH 917

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            I  + G +  +G L+  T + Y++ V A D G P  +++                F    
Sbjct: 918  IHEKHGLITLTGPLE-VTASSYEVEVIAEDMGVPKHTSSLVLIVSVYDVNDNSPVFDQLS 976

Query: 371  YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
            YEV + E EP  +    + ATD D   +  + Y+I GGNT   F I      G + +   
Sbjct: 977  YEVLIPESEPVNSRFFKVEATDKDSGFNGEIVYDIAGGNTGDVFGIFPD---GQLYIKAE 1033

Query: 429  LDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGT 486
            LD + + RY L + A D      +A V +++   D N+  P+F +  Y     E+   G+
Sbjct: 1034 LDREIQERYNLVLVARDRAVEPLSASVNVSVILDDVNDNRPLFNSTNYVFHFEEEQQRGS 1093

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM-- 544
             V  V A D D G N+++ Y+      N         F +N  TG +++    DRE++  
Sbjct: 1094 LVGRVFAEDKDFGPNSEVRYTFEMPQPN---------FELNAITGELSSTAQFDRESLMR 1144

Query: 545  ----SGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
                + +   V + D G+P  L D   V++ + D+NDN+P F + +Y A++ E A   T 
Sbjct: 1145 QRGAAVFSFVVVSSDQGLPRPLKDQAKVQVYIQDINDNQPKFTKDVYQASVSESAPNVTQ 1204

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
            + +V A+D D   NG + Y +  +  EEG F+ID +SG I     LD E+ +++ LK +A
Sbjct: 1205 LLRVSASDVDENKNGLVQYHV-AEGNEEGQFMIDSSSGQITLVGKLDYETTSSYSLKIIA 1263

Query: 660  IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
            +DGG  P SS+ ++ I + D ND+ P F    ++  + EN  IG  +  + A D D GPN
Sbjct: 1264 VDGGAEPLSSSCMLSISVLDENDNSPSFPKSSVSVDVLENMRIGELVASVTATDTDSGPN 1323

Query: 720  AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776
            A + YSI   ++  +FS+    GS    +  +  LDYE+ +  Y+L + A     P   +
Sbjct: 1324 ADITYSITATNNHGTFSISPNTGS----IFLVKKLDYET-QSVYKLNVSAKDNGRPSRSS 1378

Query: 777  DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAY--DADVTDKLQYRILS 833
             + V I V D NDN P+      IF +  +  PV      + A+  DAD+  +L+Y I+ 
Sbjct: 1379 SIPVIIHVRDFNDNPPIFTPGD-IFKSIPENLPVATSVMMIVAHDTDADINGQLEYSIVQ 1437

Query: 834  G-NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
                 N   ++ +TG +  + +++     L  + V  TD
Sbjct: 1438 QVPRGNHFSIDASTGVLYTNQEVDREFSNLFELTVKATD 1476



 Score =  312 bits (766), Expect = 9e-83
 Identities = 208/624 (33%), Positives = 313/624 (50%), Gaps = 47/624 (7%)

Query: 136  IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV------------GA 183
            + + + D NDN P F      V+++E++   D   I ++ ATDAD             G 
Sbjct: 1782 VEITLQDVNDNPPVFPNDILDVTIEENVG--DGFKIMQLTATDADELPYVSWLLFPSEGP 1839

Query: 184  NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
            N+ + Y II G     F ID  SGD+   K LD E+   Y L++RA DG    +S+  +L
Sbjct: 1840 NALVTYTIISGADD-SFRIDPESGDLIATKKLDRERRSKYSLLVRADDG---KQSSDMRL 1895

Query: 244  LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
             I ++D+ND++P+F  + +   + E+   G  +  + A D+D GVN E+TY++ + D   
Sbjct: 1896 NITVKDINDHSPKFSRATYSFDIPEDTTAGSIVAAILASDSDSGVNGEVTYSLEEDDE-- 1953

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
              D    ++P +G    +  LD E Q  Y L   A DGG   +++T              
Sbjct: 1954 --DETFLLNPVTGVFNVTRVLDYELQRYYILTARAQDGGG--QASTVRVYFNVLDVNDNP 2009

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRG 421
              F    Y   ++E  P G+ VVT+ A+DAD+  + +L Y I  G+ +G F IT     G
Sbjct: 2010 PVFETTTYSASVSESLPAGSSVVTVVASDADDGPNAQLFYRIASGDPQGHFLITKD---G 2066

Query: 422  LITVAQPLDFKQERRYVLTVSATDSGGR-----SDTAMVQINITDANNYAPVFENAPYTA 476
             +   + LD + +  Y L ++  D         + TA V + + D N+  P F +   T 
Sbjct: 2067 NLRTQKALDRETQSFYNLVITVNDLAPPPMTRFTSTAQVSVILLDVNDCPPTFTSQKMTY 2126

Query: 477  SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
             + E+ P+ T VL V A+DSD G N+ + YSL    SN+        F I    G +   
Sbjct: 2127 -IQENTPVDTVVLAVHASDSDSGPNSYVEYSLHGPFSNK--------FSIGTIDGDVRLV 2177

Query: 537  KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
              LDRE +S Y LTV A D G P LS T DV + V+DVNDN P F Q +Y   I E+ L 
Sbjct: 2178 GELDREEISNYTLTVVATDKGEPPLSSTMDVTMVVLDVNDNTPSFSQNIYDIEIEENTLT 2237

Query: 597  GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
            GT V QV ATDAD G NG+I + +   + +   F I   +G+I   + LDRE+ +++ L 
Sbjct: 2238 GTDVIQVFATDADEGTNGQIRFSISGSNTD---FRIYSVTGMISVARQLDREARSSYSLL 2294

Query: 657  AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN-SPIGTTIGEIRAHDPD 715
              A D G+ P+     V+I + D+ND  PVFE    T  + EN   + T + ++ A D D
Sbjct: 2295 VQATDRGSSPRMDQATVNIVLLDVNDCAPVFELSPYTVRVQENLENLPTNVLQVVARDDD 2354

Query: 716  EGPNAVVHYSIKGGDDSNSFSLET 739
            +G N  + Y + GG+D  +FSL +
Sbjct: 2355 QGANGQLSYMLSGGNDDGAFSLSS 2378



 Score =  309 bits (759), Expect = 6e-82
 Identities = 247/874 (28%), Positives = 388/874 (44%), Gaps = 62/874 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            IN+ D ND  P F    +  S+ E A +GT +L L ATD D+G N  + ++ +  T    
Sbjct: 546  INITDVNDQVPTFTQSTFHVSLAEHAPAGTQLLVLSATDGDLGPNGTMRFSFDAETP--- 602

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                            Q  FR+D  SG L T   LDRE+ A Y + V+ TD  SP    L
Sbjct: 603  -------------AAAQGRFRLDPLSGRLSTAVELDREEQASYLLHVQVTDGGSP---PL 646

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             S   ++V + D NDN P F    Y  +V E  +      +  + ATD D+G N  ++Y 
Sbjct: 647  RSAGKVNVTLRDVNDNRPVFYPLQYFANVKE--NEPSGSYVTTVSATDPDLGRNGTVKYM 704

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIRD 249
            I  G+    F I+  +G +S +  LD E+  +Y+L + A D GS  RS+T  ++ +++ D
Sbjct: 705  ITAGDA-ATFHINGNTGKISTLVPLDREEKTTYQLQVTAAD-GSGLRSHTPAIVTVSVLD 762

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
              DN P F    +   + ENV +G  +  V A   D  +N  ++Y +T  D  G     +
Sbjct: 763  TQDNPPVFSQKGYSFVMFENVGVGTVVGTVSATTVD--LNTNVSYLITSGDQRG-----L 815

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
                 +G +  S  +DRE Q+ +QL V A  G     +   +              F+  
Sbjct: 816  FAVNSAGQITASSPIDREEQSFHQLKVVARAG---QITGEVSVNITVKDLNDNAPRFIHA 872

Query: 370  QYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
               V   E+   G  +    A+D DE  N +       N RG F I  ++  GLIT+  P
Sbjct: 873  VEHVSAVENWSTGHTIFQAKASDPDEGANGVVVYSLKQNPRGLFHIHEKH--GLITLTGP 930

Query: 429  LDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
            L+      Y + V A D G    T+  ++ +++ D N+ +PVF+   Y   + E  P+ +
Sbjct: 931  LEVTAS-SYEVEVIAEDMGVPKHTSSLVLIVSVYDVNDNSPVFDQLSYEVLIPESEPVNS 989

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
                V ATD D G N +I Y ++   + +        F I P  G +     LDRE    
Sbjct: 990  RFFKVEATDKDSGFNGEIVYDIAGGNTGDV-------FGIFPD-GQLYIKAELDREIQER 1041

Query: 547  YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
            Y L + ARD  V  LS + +V + + DVNDN P+F    Y  +  E+   G+ V +V A 
Sbjct: 1042 YNLVLVARDRAVEPLSASVNVSVILDDVNDNRPLFNSTNYVFHFEEEQQRGSLVGRVFAE 1101

Query: 607  DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV------ATHDLKAVAI 660
            D D G N  + Y     +  + +F ++  +G + +    DRES+      A      V+ 
Sbjct: 1102 DKDFGPNSEVRYTF---EMPQPNFELNAITGELSSTAQFDRESLMRQRGAAVFSFVVVSS 1158

Query: 661  DGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
            D G P P      V + I+DIND+ P F  D     +SE++P  T +  + A D DE  N
Sbjct: 1159 DQGLPRPLKDQAKVQVYIQDINDNQPKFTKDVYQASVSESAPNVTQLLRVSASDVDENKN 1218

Query: 720  AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR 779
             +V Y +  G++   F +++  G  +  LV  +D +  S      + +   + PL +   
Sbjct: 1219 GLVQYHVAEGNEEGQFMIDSSSG--QITLVGKLDYETTSSYSLKIIAVDGGAEPLSSSCM 1276

Query: 780  VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNA 837
            + I V D NDN+P      +  +  ++         V A D D      + Y I + NN 
Sbjct: 1277 LSISVLDENDNSPSFPKSSVSVDVLENMRIGELVASVTATDTDSGPNADITYSITATNNH 1336

Query: 838  NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
                ++  TGS+ L  +L+     +  + VS  D
Sbjct: 1337 GTFSISPNTGSIFLVKKLDYETQSVYKLNVSAKD 1370



 Score =  307 bits (753), Expect = 3e-81
 Identities = 221/662 (33%), Positives = 329/662 (49%), Gaps = 44/662 (6%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I + D ND+ PVF     + ++ E    G  ++ L ATD D     E+ Y   L+    
Sbjct: 1783 EITLQDVNDNPPVFPNDILDVTIEENVGDGFKIMQLTATDAD-----ELPYVSWLLFPSE 1837

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
              P               D FRID  SG L+    LDRE+ ++Y++LV+A D       +
Sbjct: 1838 -GPN--ALVTYTIISGADDSFRIDPESGDLIATKKLDRERRSKYSLLVRADD------GK 1888

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             SS   +++ + D ND+ P+FS  TY+  + ED   T   ++A I A+D+D G N  + Y
Sbjct: 1889 QSSDMRLNITVKDINDHSPKFSRATYSFDIPED--TTAGSIVAAILASDSDSGVNGEVTY 1946

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            ++   +    F ++ ++G  ++ + LDYE  R Y L  RAQDGG   +++T ++  N+ D
Sbjct: 1947 SLEEDDEDETFLLNPVTGVFNVTRVLDYELQRYYILTARAQDGG--GQASTVRVYFNVLD 2004

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            VNDN P F T+ +  SVSE++P G S+V V A DAD+G NA+L Y +   D  G+    I
Sbjct: 2005 VNDNPPVFETTTYSASVSESLPAGSSVVTVVASDADDGPNAQLFYRIASGDPQGH--FLI 2062

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR---SATATXXXXXXXXXXXXXXF 366
            T D   G + T   LDRETQ+ Y L++T  D   PP    ++TA               F
Sbjct: 2063 TKD---GNLRTQKALDRETQSFYNLVITVNDLAPPPMTRFTSTAQVSVILLDVNDCPPTF 2119

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT-GGNTRGRFSITSQNGRGLITV 425
               Q    + E+ P  T V+ + A+D+D     + E +  G    +FSI + +G   + +
Sbjct: 2120 -TSQKMTYIQENTPVDTVVLAVHASDSDSGPNSYVEYSLHGPFSNKFSIGTIDGD--VRL 2176

Query: 426  AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
               LD ++   Y LTV ATD G    S T  V + + D N+  P F    Y   + E+  
Sbjct: 2177 VGELDREEISNYTLTVVATDKGEPPLSSTMDVTMVVLDVNDNTPSFSQNIYDIEIEENTL 2236

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
             GT V+ V ATD+D G N QI +S+S           +  F I   TG I+  + LDRE 
Sbjct: 2237 TGTDVIQVFATDADEGTNGQIRFSISGS---------NTDFRIYSVTGMISVARQLDREA 2287

Query: 544  MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED-ALVGTSVSQ 602
             S Y L V A D G     D   V I ++DVND  PVF+   YT  + E+   + T+V Q
Sbjct: 2288 RSSYSLLVQATDRGSSPRMDQATVNIVLLDVNDCAPVFELSPYTVRVQENLENLPTNVLQ 2347

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
            V A D D G NG++ Y L     ++G+F +  + G +R  + +DRE+   + L   A D 
Sbjct: 2348 VVARDDDQGANGQLSYMLS-GGNDDGAFSLS-SGGQLRLTQTVDREARGEYILLITATDS 2405

Query: 663  GT 664
            GT
Sbjct: 2406 GT 2407



 Score =  301 bits (739), Expect = 2e-79
 Identities = 257/883 (29%), Positives = 406/883 (45%), Gaps = 69/883 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            ++VLD  D+ PVF  + Y   + E    GT V T+ AT  D+  N  V Y I   + D  
Sbjct: 758  VSVLDTQDNPPVFSQKGYSFVMFENVGVGTVVGTVSATTVDL--NTNVSYLI--TSGDQ- 812

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                            + +F ++  +G +   + +DRE+ + + + V A       + ++
Sbjct: 813  ----------------RGLFAVNS-AGQITASSPIDREEQSFHQLKVVAR------AGQI 849

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +   ++++ + D NDN P+F      VS  E+ S      I + KA+D D GAN  + Y+
Sbjct: 850  TGEVSVNITVKDLNDNAPRFIHAVEHVSAVENWST--GHTIFQAKASDPDEGANGVVVYS 907

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            +   N +  F I    G ++L   L+     SY + + A+D G P  +++  L++++ DV
Sbjct: 908  L-KQNPRGLFHIHEKHGLITLTGPLEVT-ASSYEVEVIAEDMGVPKHTSSLVLIVSVYDV 965

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN+P F    ++  + E+ P+     +V+A D D G N E+ Y +   + TG+V     
Sbjct: 966  NDNSPVFDQLSYEVLIPESEPVNSRFFKVEATDKDSGFNGEIVYDIAGGN-TGDV---FG 1021

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            I P  G +Y   +LDRE Q +Y L++ A D    P SA+                F    
Sbjct: 1022 IFP-DGQLYIKAELDREIQERYNLVLVARDRAVEPLSASVNVSVILDDVNDNRPLFNSTN 1080

Query: 371  YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
            Y     E++  G+ V  + A D D         T    +  F + +  G    T     +
Sbjct: 1081 YVFHFEEEQQRGSLVGRVFAEDKDFGPNSEVRYTFEMPQPNFELNAITGELSSTAQFDRE 1140

Query: 431  FKQERR----YVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
                +R    +   V ++D G      D A VQ+ I D N+  P F    Y ASV E AP
Sbjct: 1141 SLMRQRGAAVFSFVVVSSDQGLPRPLKDQAKVQVYIQDINDNQPKFTKDVYQASVSESAP 1200

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
              T +L VSA+D D   N  + Y ++    NE     + QF+I+  +G IT    LD ET
Sbjct: 1201 NVTQLLRVSASDVDENKNGLVQYHVAE--GNE-----EGQFMIDSSSGQITLVGKLDYET 1253

Query: 544  MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
             S Y L + A DGG   LS +  + ISV+D NDN P F +   + +++E+  +G  V+ V
Sbjct: 1254 TSSYSLKIIAVDGGAEPLSSSCMLSISVLDENDNSPSFPKSSVSVDVLENMRIGELVASV 1313

Query: 604  GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
             ATD D G N  I Y +   +   G+F I P +G I   K LD E+ + + L   A D G
Sbjct: 1314 TATDTDSGPNADITYSITATNNH-GTFSISPNTGSIFLVKKLDYETQSVYKLNVSAKDNG 1372

Query: 664  TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
             P +SS++ V I + D ND+PP+F    +   I EN P+ T++  I AHD D   N  + 
Sbjct: 1373 RPSRSSSIPVIIHVRDFNDNPPIFTPGDIFKSIPENLPVATSVMMIVAHDTDADINGQLE 1432

Query: 724  YSI-KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR--- 779
            YSI +     N FS++   G     L T  ++D E     +EL ++A    +  + R   
Sbjct: 1433 YSIVQQVPRGNHFSIDASTGV----LYTNQEVDREFSNL-FELTVKATDQAVPLETRRFA 1487

Query: 780  ---VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSG 834
               V I VTD NDN P       +     +         V AYD D     +++Y ++ G
Sbjct: 1488 LKNVTIWVTDQNDNIPTFLSQNALVAE-PNIMIGSILTTVVAYDPDEGANGEVEYELVEG 1546

Query: 835  NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIK 877
            ++   I ++  +G + L+ QL  +   + ++ VS TD   E K
Sbjct: 1547 DSGTFI-MDRYSGDIRLASQLVPS-QLVYSLTVSATDHGTERK 1587



 Score =  293 bits (719), Expect = 5e-77
 Identities = 226/731 (30%), Positives = 348/731 (47%), Gaps = 62/731 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            ++V D ND+SPVF+   YE  + E     +    ++ATD+D G N E+ Y I        
Sbjct: 960  VSVYDVNDNSPVFDQLSYEVLIPESEPVNSRFFKVEATDKDSGFNGEIVYDI-------- 1011

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                             DVF I    G L  +A LDRE   RY +++ A D+A    + L
Sbjct: 1012 -----------AGGNTGDVFGIFP-DGQLYIKAELDREIQERYNLVLVARDRAV---EPL 1056

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S++  + V + D NDN P F+   Y    +E+       ++ ++ A D D G NS +RY 
Sbjct: 1057 SASVNVSVILDDVNDNRPLFNSTNYVFHFEEEQQ--RGSLVGRVFAEDKDFGPNSEVRYT 1114

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR------LVIRAQDGGSPSR-SNTTQL 243
                  Q  F +++++G++S     D E +   R       V+ + D G P    +  ++
Sbjct: 1115 F--EMPQPNFELNAITGELSSTAQFDRESLMRQRGAAVFSFVVVSSDQGLPRPLKDQAKV 1172

Query: 244  LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
             + I+D+NDN P+F   ++Q SVSE+ P    ++RV A D DE  N  + Y + +    G
Sbjct: 1173 QVYIQDINDNQPKFTKDVYQASVSESAPNVTQLLRVSASDVDENKNGLVQYHVAE----G 1228

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
            N +    ID  SG +   G+LD ET + Y L + A DGG  P S++              
Sbjct: 1229 NEEGQFMIDSSSGQITLVGKLDYETTSSYSLKIIAVDGGAEPLSSSCMLSISVLDENDNS 1288

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRG 421
              F      V++ E+   G  V ++TATD D      + Y IT  N  G FSI+   G  
Sbjct: 1289 PSFPKSSVSVDVLENMRIGELVASVTATDTDSGPNADITYSITATNNHGTFSISPNTGS- 1347

Query: 422  LITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVF 479
             I + + LD++ +  Y L VSA D+G   RS +  V I++ D N+  P+F       S+ 
Sbjct: 1348 -IFLVKKLDYETQSVYKLNVSAKDNGRPSRSSSIPVIIHVRDFNDNPPIFTPGDIFKSIP 1406

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
            E+ P+ T+V+++ A D+D  IN Q+ YS+  ++      +H   F I+  TG + TN+ +
Sbjct: 1407 ENLPVATSVMMIVAHDTDADINGQLEYSIVQQVPR---GNH---FSIDASTGVLYTNQEV 1460

Query: 540  DRETMSGYLLTVTARDGGVPSLSDT---TDVEISVVDVNDNEPVFKQQLYTANIME-DAL 595
            DRE  + + LTV A D  VP  +      +V I V D NDN P F  Q   A + E + +
Sbjct: 1461 DREFSNLFELTVKATDQAVPLETRRFALKNVTIWVTDQNDNIPTFLSQ--NALVAEPNIM 1518

Query: 596  VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655
            +G+ ++ V A D D G NG + YEL   D   G+F++D  SG IR    L   S   + L
Sbjct: 1519 IGSILTTVVAYDPDEGANGEVEYELVEGD--SGTFIMDRYSGDIRLASQLV-PSQLVYSL 1575

Query: 656  KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
               A D GT  ++S   + I ++ ++   PVF        + E  P GT +  + A  P 
Sbjct: 1576 TVSATDHGTERKTSRTDLTIILQGLDG--PVFSQPKYITILKEGQPPGTNVISLDASSP- 1632

Query: 716  EGPNAVVHYSI 726
             G  + V Y I
Sbjct: 1633 RGSTSKVEYFI 1643



 Score =  278 bits (681), Expect = 2e-72
 Identities = 246/882 (27%), Positives = 407/882 (46%), Gaps = 84/882 (9%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            Q+ + D ND+ P F    Y+ASV E A + T +L + A+D D  KN  V+Y +       
Sbjct: 1173 QVYIQDINDNQPKFTKDVYQASVSESAPNVTQLLRVSASDVDENKNGLVQYHV------- 1225

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                             +  F ID  SG +     LD E  + Y++ + A D  +   + 
Sbjct: 1226 ------------AEGNEEGQFMIDSSSGQITLVGKLDYETTSSYSLKIIAVDGGA---EP 1270

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            LSS+  + ++++D+NDN P F + + +V V E++ + +  ++A + ATD D G N+ I Y
Sbjct: 1271 LSSSCMLSISVLDENDNSPSFPKSSVSVDVLENMRIGE--LVASVTATDTDSGPNADITY 1328

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            +I   N    FSI   +G + LVK LDYE    Y+L + A+D G PSRS++  ++I++RD
Sbjct: 1329 SITATNNHGTFSISPNTGSIFLVKKLDYETQSVYKLNVSAKDNGRPSRSSSIPVIIHVRD 1388

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
             NDN P F      +S+ EN+P+  S++ + A+D D  +N +L Y++  +   GN     
Sbjct: 1389 FNDNPPIFTPGDIFKSIPENLPVATSVMMIVAHDTDADINGQLEYSIVQQVPRGN---HF 1445

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP---PRSATATXXXXXXXXXXXXXXF 366
            +ID  +G +YT+ ++DRE    ++L V ATD   P    R A                 F
Sbjct: 1446 SIDASTGVLYTNQEVDREFSNLFELTVKATDQAVPLETRRFALKNVTIWVTDQNDNIPTF 1505

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLIT 424
            +  Q  +    +   G+ + T+ A D DE  +  + YE+  G++ G F +   +G   I 
Sbjct: 1506 L-SQNALVAEPNIMIGSILTTVVAYDPDEGANGEVEYELVEGDS-GTFIMDRYSGD--IR 1561

Query: 425  VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
            +A  L    +  Y LTVSATD G    T+   + I       PVF    Y   + E  P 
Sbjct: 1562 LASQL-VPSQLVYSLTVSATDHGTERKTSRTDLTIILQGLDGPVFSQPKYITILKEGQPP 1620

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            GT V+ + A+ S  G  +++ Y + +  S    A   + F I   +G I T   LD    
Sbjct: 1621 GTNVISLDAS-SPRGSTSKVEYFIVAVHSGGKAA--GRLFTIGRHSGVIQTAAELD---- 1673

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
                     R+ G    SD   V++  ++ + ++P   Q+  T N+          ++ G
Sbjct: 1674 ---------REQG----SDLYLVDVYAIESDASQPR-TQRAETQNLGGFLDRLDQENRAG 1719

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            +  A   L   +     P  + +   V+  + G   T+     E +    ++ +++   T
Sbjct: 1720 SPSAAGWLPSTVRLWKQPVPQPQLEGVLPGSLG--GTDNVDPFEFLG--QIQRLSLGVCT 1775

Query: 665  PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD----------- 713
            P  ++ + V I ++D+ND+PPVF +D L   I EN   G  I ++ A D           
Sbjct: 1776 P--NNLMEVEITLQDVNDNPPVFPNDILDVTIEENVGDGFKIMQLTATDADELPYVSWLL 1833

Query: 714  -PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP 772
             P EGPNA+V Y+I  G D +SF ++   G    +L+    LD E  R KY L++RA   
Sbjct: 1834 FPSEGPNALVTYTIISGAD-DSFRIDPESG----DLIATKKLDRER-RSKYSLLVRADDG 1887

Query: 773  PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYR 830
               +D+R+ I V D+ND++P        F+  +D         + A D+D  V  ++ Y 
Sbjct: 1888 KQSSDMRLNITVKDINDHSPKFSRATYSFDIPEDTTAGSIVAAILASDSDSGVNGEVTYS 1947

Query: 831  ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            +   +     LLN  TG   ++  L+  + +   +     DG
Sbjct: 1948 LEEDDEDETFLLNPVTGVFNVTRVLDYELQRYYILTARAQDG 1989



 Score =  273 bits (669), Expect = 5e-71
 Identities = 208/658 (31%), Positives = 316/658 (48%), Gaps = 54/658 (8%)

Query: 238  SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD------------ 285
            +N  ++ I ++DVNDN P F   +   ++ ENV  G+ I+++ A DAD            
Sbjct: 1777 NNLMEVEITLQDVNDNPPVFPNDILDVTIEENVGDGFKIMQLTATDADELPYVSWLLFPS 1836

Query: 286  EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP 345
            EG NA +TYT+         D    IDP SG +  + +LDRE ++KY LLV A DG    
Sbjct: 1837 EGPNALVTYTI-----ISGADDSFRIDPESGDLIATKKLDRERRSKYSLLVRADDG---K 1888

Query: 346  RSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI 403
            +S+                 F    Y  ++ ED   G+ V  + A+D+D   +  + Y +
Sbjct: 1889 QSSDMRLNITVKDINDHSPKFSRATYSFDIPEDTTAGSIVAAILASDSDSGVNGEVTYSL 1948

Query: 404  TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDAN 463
               +    F +      G+  V + LD++ +R Y+LT  A D GG++ T  V  N+ D N
Sbjct: 1949 EEDDEDETFLLNPVT--GVFNVTRVLDYELQRYYILTARAQDGGGQASTVRVYFNVLDVN 2006

Query: 464  NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523
            +  PVFE   Y+ASV E  P G++V+ V A+D+D G NAQ+ Y ++   S +   H    
Sbjct: 2007 DNPPVFETTTYSASVSESLPAGSSVVTVVASDADDGPNAQLFYRIA---SGDPQGH---- 2059

Query: 524  FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL---SDTTDVEISVVDVNDNEPV 580
            F+I  + G + T K LDRET S Y L +T  D   P +   + T  V + ++DVND  P 
Sbjct: 2060 FLIT-KDGNLRTQKALDRETQSFYNLVITVNDLAPPPMTRFTSTAQVSVILLDVNDCPPT 2118

Query: 581  FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640
            F  Q  T  I E+  V T V  V A+D+D G N  + Y L         F I    G +R
Sbjct: 2119 FTSQKMT-YIQENTPVDTVVLAVHASDSDSGPNSYVEYSL--HGPFSNKFSIGTIDGDVR 2175

Query: 641  TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700
                LDRE ++ + L  VA D G PP SST+ V + + D+ND+ P F  +     I EN+
Sbjct: 2176 LVGELDREEISNYTLTVVATDKGEPPLSSTMDVTMVVLDVNDNTPSFSQNIYDIEIEENT 2235

Query: 701  PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760
              GT + ++ A D DEG N  + +SI G   SN+   + R  S    +     LD E+ R
Sbjct: 2236 LTGTDVIQVFATDADEGTNGQIRFSISG---SNT---DFRIYSVTGMISVARQLDREA-R 2288

Query: 761  KKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPV--MKDFQIIFNNYKDCFPVGPFGR 815
              Y L+++A    S P  +   V I++ DVND APV  +  + +      +  P     +
Sbjct: 2289 SSYSLLVQATDRGSSPRMDQATVNIVLLDVNDCAPVFELSPYTVRVQENLENLPTNVL-Q 2347

Query: 816  VPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            V A D D     +L Y +  GN+     L+ + G + L+  ++        + ++ TD
Sbjct: 2348 VVARDDDQGANGQLSYMLSGGNDDGAFSLS-SGGQLRLTQTVDREARGEYILLITATD 2404



 Score =  250 bits (613), Expect = 3e-64
 Identities = 246/919 (26%), Positives = 410/919 (44%), Gaps = 77/919 (8%)

Query: 2    SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
            S+P  IH    V D ND+ P+F       S+ E     T+V+ + A D D   N ++EY+
Sbjct: 1379 SIPVIIH----VRDFNDNPPIFTPGDIFKSIPENLPVATSVMMIVAHDTDADINGQLEYS 1434

Query: 62   IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121
            I         P               + F ID  +G L T   +DRE    + + VKATD
Sbjct: 1435 IVQQV-----PRG-------------NHFSIDASTGVLYTNQEVDREFSNLFELTVKATD 1476

Query: 122  QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181
            QA P+  R  +   + + + D NDN P F  +   V+   + ++    ++  + A D D 
Sbjct: 1477 QAVPLETRRFALKNVTIWVTDQNDNIPTFLSQNALVA---EPNIMIGSILTTVVAYDPDE 1533

Query: 182  GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
            GAN  + Y ++ G++   F +D  SGD+ L   L   Q+  Y L + A D G+  +++ T
Sbjct: 1534 GANGEVEYELVEGDSG-TFIMDRYSGDIRLASQLVPSQL-VYSLTVSATDHGTERKTSRT 1591

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
             L I ++ +  + P F    +   + E  P G +++ + A  +  G  +++ Y +     
Sbjct: 1592 DLTIILQGL--DGPVFSQPKYITILKEGQPPGTNVISLDA-SSPRGSTSKVEYFIVAVHS 1648

Query: 302  TGN-VDLPITIDPRSGWVYTSGQLDRETQAKYQLL-VTATDG-GDPPRSATATXXXXXXX 358
             G       TI   SG + T+ +LDRE  +   L+ V A +     PR+  A        
Sbjct: 1649 GGKAAGRLFTIGRHSGVIQTAAELDREQGSDLYLVDVYAIESDASQPRTQRAETQNLGGF 1708

Query: 359  XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQN 418
                      G      A   P    +          +  L   + G +    F    Q 
Sbjct: 1709 LDRLDQENRAG--SPSAAGWLPSTVRLWKQPVPQPQLEGVLPGSLGGTDNVDPFEFLGQI 1766

Query: 419  GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASV 478
             R  + V  P +  +    +  V+       +D     +++T   N    F+    TA+ 
Sbjct: 1767 QRLSLGVCTPNNLMEVEITLQDVNDNPPVFPNDI----LDVTIEENVGDGFKIMQLTATD 1822

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             ++ P  + +L  S      G NA +TY++        ++  D  F I+P++G +   K 
Sbjct: 1823 ADELPYVSWLLFPSE-----GPNALVTYTI--------ISGADDSFRIDPESGDLIATKK 1869

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            LDRE  S Y L V A DG     S    + I+V D+ND+ P F +  Y+ +I ED   G+
Sbjct: 1870 LDRERRSKYSLLVRADDG---KQSSDMRLNITVKDINDHSPKFSRATYSFDIPEDTTAGS 1926

Query: 599  SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
             V+ + A+D+D G+NG + Y L+  D +E +F+++P +GV    + LD E    + L A 
Sbjct: 1927 IVAAILASDSDSGVNGEVTYSLEEDDEDE-TFLLNPVTGVFNVTRVLDYELQRYYILTAR 1985

Query: 659  AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
            A DGG   Q+STV V+  + D+ND+PPVFE+   +  +SE+ P G+++  + A D D+GP
Sbjct: 1986 AQDGG--GQASTVRVYFNVLDVNDNPPVFETTTYSASVSESLPAGSSVVTVVASDADDGP 2043

Query: 719  NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPL- 774
            NA + Y I  GD    F L T+ G+    L T   LD E+ +  Y LVI     A PP+ 
Sbjct: 2044 NAQLFYRIASGDPQGHF-LITKDGN----LRTQKALDRET-QSFYNLVITVNDLAPPPMT 2097

Query: 775  --WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDAD--VTDKLQY 829
               +  +V +++ DVND  P     ++ +   ++  PV      V A D+D      ++Y
Sbjct: 2098 RFTSTAQVSVILLDVNDCPPTFTSQKMTY--IQENTPVDTVVLAVHASDSDSGPNSYVEY 2155

Query: 830  RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLIT 888
              L G  +N   +    G + L  +L+       T+ V  TD G   + + M +++ ++ 
Sbjct: 2156 S-LHGPFSNKFSIGTIDGDVRLVGELDREEISNYTLTVVATDKGEPPLSSTMDVTMVVLD 2214

Query: 889  EEMLLNSITVRLNDMTAEQ 907
                  S +  + D+  E+
Sbjct: 2215 VNDNTPSFSQNIYDIEIEE 2233



 Score =  247 bits (604), Expect = 4e-63
 Identities = 211/674 (31%), Positives = 314/674 (46%), Gaps = 69/674 (10%)

Query: 15   DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
            D ND+ P+F    Y     E    G+ V  + A D+D G N+EV YT E+          
Sbjct: 1068 DVNDNRPLFNSTNYVFHFEEEQQRGSLVGRVFAEDKDFGPNSEVRYTFEMP--------- 1118

Query: 75   AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR------YTVLVKATDQASPVSD 128
                        Q  F ++  +G L + A  DRE + R      ++ +V ++DQ  P   
Sbjct: 1119 ------------QPNFELNAITGELSSTAQFDRESLMRQRGAAVFSFVVVSSDQGLPRP- 1165

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             L   A + V I D NDN P+F++  Y  SV E  S  +   + ++ A+D D   N  ++
Sbjct: 1166 -LKDQAKVQVYIQDINDNQPKFTKDVYQASVSE--SAPNVTQLLRVSASDVDENKNGLVQ 1222

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            Y +  GN + QF IDS SG ++LV  LDYE   SY L I A DGG+   S++  L I++ 
Sbjct: 1223 YHVAEGNEEGQFMIDSSSGQITLVGKLDYETTSSYSLKIIAVDGGAEPLSSSCMLSISVL 1282

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            D NDN+P F  S     V EN+ IG  +  V A D D G NA++TY++T  +  G     
Sbjct: 1283 DENDNSPSFPKSSVSVDVLENMRIGELVASVTATDTDSGPNADITYSITATNNHGT---- 1338

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
             +I P +G ++   +LD ETQ+ Y+L V+A D G P RS++                F P
Sbjct: 1339 FSISPNTGSIFLVKKLDYETQSVYKLNVSAKDNGRPSRSSSIPVIIHVRDFNDNPPIFTP 1398

Query: 369  GQYEVELAEDEPPGTPVVTLTA--TDADEDNRLHYEITGGNTRG-RFSITSQNGRGLITV 425
            G     + E+ P  T V+ + A  TDAD + +L Y I     RG  FSI +    G++  
Sbjct: 1399 GDIFKSIPENLPVATSVMMIVAHDTDADINGQLEYSIVQQVPRGNHFSIDAST--GVLYT 1456

Query: 426  AQPLDFKQERRYVLTVSATDSGGRSDTAM-----VQINITDANNYAPVFENAPYTASVFE 480
             Q +D +    + LTV ATD     +T       V I +TD N+  P F      A V E
Sbjct: 1457 NQEVDREFSNLFELTVKATDQAVPLETRRFALKNVTIWVTDQNDNIPTF--LSQNALVAE 1514

Query: 481  -DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKL 538
             +  IG+ +  V A D D G N ++ Y        E V      F+++  +G I   ++L
Sbjct: 1515 PNIMIGSILTTVVAYDPDEGANGEVEY--------ELVEGDSGTFIMDRYSGDIRLASQL 1566

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            +  + +  Y LTV+A D G    +  TD+ I +  ++   PVF Q  Y   + E    GT
Sbjct: 1567 VPSQLV--YSLTVSATDHGTERKTSRTDLTIILQGLDG--PVFSQPKYITILKEGQPPGT 1622

Query: 599  SVSQVGATDADVGLNGRIHY---ELDPKDREEGS-FVIDPASGVIRTNKALDRE---SVA 651
            +V  + A+ +  G   ++ Y    +    +  G  F I   SGVI+T   LDRE    + 
Sbjct: 1623 NVISLDAS-SPRGSTSKVEYFIVAVHSGGKAAGRLFTIGRHSGVIQTAAELDREQGSDLY 1681

Query: 652  THDLKAVAIDGGTP 665
              D+ A+  D   P
Sbjct: 1682 LVDVYAIESDASQP 1695



 Score =  246 bits (603), Expect = 5e-63
 Identities = 185/560 (33%), Positives = 267/560 (47%), Gaps = 55/560 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D NDHSP F    Y   + E  ++G+ V  + A+D D G N EV Y++E       
Sbjct: 1897 ITVKDINDHSPKFSRATYSFDIPEDTTAGSIVAAILASDSDSGVNGEVTYSLEE------ 1950

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            + ED             + F ++  +G       LD E    Y +  +A D         
Sbjct: 1951 DDED-------------ETFLLNPVTGVFNVTRVLDYELQRYYILTARAQDGGGQ----- 1992

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +ST  ++ N++D NDN P F   TY+ SV E +    +  +  + A+DAD G N+ + Y 
Sbjct: 1993 ASTVRVYFNVLDVNDNPPVFETTTYSASVSESLPAGSS--VVTVVASDADDGPNAQLFYR 2050

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS---NTTQLLINI 247
            I  G+ Q  F I    G++   K LD E    Y LVI   D   P  +   +T Q+ + +
Sbjct: 2051 IASGDPQGHFLITK-DGNLRTQKALDRETQSFYNLVITVNDLAPPPMTRFTSTAQVSVIL 2109

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
             DVND  P F TS     + EN P+   ++ V A D+D G N+ + Y++      G    
Sbjct: 2110 LDVNDCPPTF-TSQKMTYIQENTPVDTVVLAVHASDSDSGPNSYVEYSLH-----GPFSN 2163

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
              +I    G V   G+LDRE  + Y L V ATD G+PP S+T                F 
Sbjct: 2164 KFSIGTIDGDVRLVGELDREEISNYTLTVVATDKGEPPLSSTMDVTMVVLDVNDNTPSFS 2223

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGR-FSITSQNGRGLIT 424
               Y++E+ E+   GT V+ + ATDADE  + ++ + I+G NT  R +S+T     G+I+
Sbjct: 2224 QNIYDIEIEENTLTGTDVIQVFATDADEGTNGQIRFSISGSNTDFRIYSVT-----GMIS 2278

Query: 425  VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
            VA+ LD +    Y L V ATD G   R D A V I + D N+ APVFE +PYT  V E+ 
Sbjct: 2279 VARQLDREARSSYSLLVQATDRGSSPRMDQATVNIVLLDVNDCAPVFELSPYTVRVQENL 2338

Query: 483  P-IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
              + T VL V A D D G N Q++Y LS         + D  F ++   G +   + +DR
Sbjct: 2339 ENLPTNVLQVVARDDDQGANGQLSYMLSG-------GNDDGAFSLS-SGGQLRLTQTVDR 2390

Query: 542  ETMSGYLLTVTARDGGVPSL 561
            E    Y+L +TA D G   L
Sbjct: 2391 EARGEYILLITATDSGTSVL 2410



 Score =  183 bits (446), Expect = 5e-44
 Identities = 145/517 (28%), Positives = 237/517 (45%), Gaps = 34/517 (6%)

Query: 372 EVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431
           E ++ E++P GT V T+       + +  +      +   FSI   +G  +I+ +  +D 
Sbjct: 33  EFQVLEEQPVGTYVGTI-------ETKPSFTYRFSESHRLFSINGSSG--VISTSAVIDR 83

Query: 432 KQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491
           +  +  V+ V    S     T  V+I + D N+ +PVF +A    S  EDA  G  V++ 
Sbjct: 84  EALQSDVINVVVLSSQPTYPTE-VRIVVLDINDNSPVFPDASIVVSFKEDASSGRQVILD 142

Query: 492 SATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ-TGA---ITTNKLLDRETMSGY 547
           +ATD+D+G N  + ++    +             +NP   GA   + +   LDRE    Y
Sbjct: 143 TATDTDIGSNG-VDHTTYRIVKGNEQRKFRLDITVNPSGEGAFLHLVSTGGLDREVTPFY 201

Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
            L +   D G P       V +++ D+NDN P F++ LY A+++EDA VG+S+ QV A+D
Sbjct: 202 QLLIEVEDKGEPKTFGYLQVNVTIQDINDNPPSFERDLYQASVLEDAAVGSSILQVTASD 261

Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
            D   N  I Y LD    EE  F IDP +G I   + LD ES   + L   A+D G P  
Sbjct: 262 GDEAANAEIRYFLD----EETPFQIDPKTGTIIIKEGLDYESRREYSLTIHAVDNGVPSL 317

Query: 668 SSTVIVHIKIEDINDSPPV-----FESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAV 721
           S      IK+ D+ND+ PV     F +      + EN+ +GT +  +   D D    N  
Sbjct: 318 SGRAEATIKLLDVNDNDPVVKFRYFPTTSKFASVDENAQVGTVVALLTVSDSDSSAANGN 377

Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA--SPPLWND-- 777
           +  SI GG++   F + T    + + +     LD E     Y L +  +    P+     
Sbjct: 378 ISVSILGGNEQRHFEVHTSPVPNLSLIKVASVLDRER-ISSYNLTVSVSDNGKPVARSSF 436

Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR-VPAYDAD--VTDKLQYRILSG 834
             + I V D+ND+ P+ ++ +   +  +D  P G + + V A D D      L+Y ++SG
Sbjct: 437 ASLVIFVNDINDHPPIFQETEYRVDISED-IPKGSYIKGVSATDGDSGQNANLRYSLVSG 495

Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
           N      ++E +G +T +  L+        + +S  D
Sbjct: 496 NALGWFSISENSGLVTSAALLDREATSEVVLNISAKD 532


>UniRef50_A7SLK9 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 1677

 Score =  373 bits (917), Expect = e-101
 Identities = 284/883 (32%), Positives = 419/883 (47%), Gaps = 57/883 (6%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           I  Q+ V D ND+ P F    Y   +RE     TT     ATD D G N  V+YTI   +
Sbjct: 79  ISVQVQVDDINDNEPRFPTLYYTLRIRESMDVNTTNPINTATDPDAGNNGTVDYTI--AS 136

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
            D                 +       G +  ++T+  LDRE    Y + + ATD+ +P 
Sbjct: 137 GDN-----------TATFSLGTTACPTGSTLCVITKKPLDRETTDFYQLNITATDRGTPA 185

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
              L     I++ I+D+ND+ P F++ +Y  S+ E  +      I ++ A D D G+N  
Sbjct: 186 ---LMGYCLINITILDENDHAPVFTQNSYLGSIAE--NTKPGVSILRVSAADRDSGSNGD 240

Query: 187 IRYAIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
           I+YAI     Q    F +DS +G +   + LD+E   SY   + A DGG PS+++   + 
Sbjct: 241 IKYAIDWDAIQSNSIFDLDSSTGVIRTKQNLDFEVKNSYTFNVIASDGGVPSKNDLATVT 300

Query: 245 INIRDVNDNAPRFYTSLF-----QESV-SENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
           IN+ D NDN+P+   +        +++ SEN  I  +I  +   D D   N++    +T+
Sbjct: 301 INVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINTNIAYILVTDKDSNTNSQTELKITN 360

Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358
            D  G   +         ++     LDRE    Y L +  TD G P RS           
Sbjct: 361 GDDEGCFKVEFL---GFYFIQLQKPLDRELVPFYNLTLNVTDKGVPSRSTLGFVLIDVTD 417

Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRGRFSITS 416
                  F    Y   ++E    G+ V+ L ATD DE DN  + Y ITGGN  G F +  
Sbjct: 418 VNDNSPAFTSNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSITGGNDLGWFQVDF 477

Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPY 474
           Q+  GL+T A+PLD +Q     +T++A D G   ++ +  V + I D N+  P F  + Y
Sbjct: 478 QS--GLVTTAKPLDREQVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSY 535

Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
             ++ E A IG TVL VSATD D G N +ITY +SS     + A  +  F +N QTG + 
Sbjct: 536 KGTISEGASIGATVLQVSATDVDSGDNGRITYEISS-----SDAQVNGLFELNTQTGVLW 590

Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
           T   LDRET S Y  TV A+D G P L  +  VE+++ D+NDN PVF    Y A+IME+ 
Sbjct: 591 TKSQLDRETKSLYSFTVLAKDHGDPQLMSSVKVELTISDINDNAPVFYPVEYFASIMENE 650

Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654
             G  + QV ATDAD G N  I Y++       G+F ID ++GVI T  +LD E      
Sbjct: 651 PPG-KLLQVTATDADEGTNAVISYDI-IGGNNNGNFSIDSSTGVISTLASLDHEVEEFFS 708

Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
           L   A DGG    + T +V++ + +  D+ PVF  +   F + EN P GT +G + A   
Sbjct: 709 LIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVYENVPKGTLVGRVYATTK 768

Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---AS 771
           D+  N  + Y+I  GD +N F +++  G  K       D+D E  + +Y L + A     
Sbjct: 769 DK--NGSISYAIVSGDPTNLFLVDSTGGIIKIN----GDMDREE-KAQYLLAVIARVGTV 821

Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF---GRVPAYDADVTDKLQ 828
            PL     V I V D NDNAP      +I  +    + VG           DA     ++
Sbjct: 822 KPLSAQATVNIEVLDRNDNAPQFSTSSVIV-DIDGTWLVGQVVYNAAAVDLDAGKNGLVR 880

Query: 829 YRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
           Y+ L+ N   L+ +N T+G + L+ +L        T++V  +D
Sbjct: 881 YQ-LTSNAEGLLWINSTSGVIKLARKLTDGDETQYTVQVLASD 922



 Score =  348 bits (855), Expect = 2e-93
 Identities = 254/791 (32%), Positives = 397/791 (50%), Gaps = 53/791 (6%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQAS-PVSDRLSSTATIHVNIIDDNDNYP 148
           F  +  +G + T A +DRE   + ++ ++  + ++ P+S        + V + D NDN P
Sbjct: 42  FGFNSNTGVISTTARIDRETTTQISLQLRTLNPSNQPIS--------VQVQVDDINDNEP 93

Query: 149 QFSEKTYTVSVDEDISV-TDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS- 206
           +F    YT+ + E + V T NP+     ATD D G N  + Y I  G+    FS+ + + 
Sbjct: 94  RFPTLYYTLRIRESMDVNTTNPINT---ATDPDAGNNGTVDYTIASGDNTATFSLGTTAC 150

Query: 207 --GDVSLV---KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261
             G    V   K LD E    Y+L I A D G+P+      + I I D ND+AP F  + 
Sbjct: 151 PTGSTLCVITKKPLDRETTDFYQLNITATDRGTPALMGYCLINITILDENDHAPVFTQNS 210

Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321
           +  S++EN   G SI+RV A D D G N ++ Y + D D   +  +   +D  +G + T 
Sbjct: 211 YLGSIAENTKPGVSILRVSAADRDSGSNGDIKYAI-DWDAIQSNSI-FDLDSSTGVIRTK 268

Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX----XXFMP---GQYEVE 374
             LD E +  Y   V A+DGG P ++  AT                  ++P   G   + 
Sbjct: 269 QNLDFEVKNSYTFNVIASDGGVPSKNDLATVTINVLDTNDNSPQLKITYLPPHNGDKAIR 328

Query: 375 LAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432
            +E+    T +  +  TD D   +++   +IT G+  G F +    G   I + +PLD +
Sbjct: 329 -SENSLINTNIAYILVTDKDSNTNSQTELKITNGDDEGCFKVEFL-GFYFIQLQKPLDRE 386

Query: 433 QERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
               Y LT++ TD G   RS    V I++TD N+ +P F +  YTA++ E A  G+ VL 
Sbjct: 387 LVPFYNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQ 446

Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550
           ++ATD D G N  ++YS++    N+        F ++ Q+G +TT K LDRE +S   +T
Sbjct: 447 LNATDPDEGDNGTVSYSITG--GNDL-----GWFQVDFQSGLVTTAKPLDREQVSSVTIT 499

Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610
           +TA+D G    + +T V ++++D NDN+P F +  Y   I E A +G +V QV ATD D 
Sbjct: 500 ITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDS 559

Query: 611 GLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669
           G NGRI YE+   D +  G F ++  +GV+ T   LDRE+ + +    +A D G P   S
Sbjct: 560 GDNGRITYEISSSDAQVNGLFELNTQTGVLWTKSQLDRETKSLYSFTVLAKDHGDPQLMS 619

Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729
           +V V + I DIND+ PVF        I EN P G  + ++ A D DEG NAV+ Y I GG
Sbjct: 620 SVKVELTISDINDNAPVFYPVEYFASIMENEPPGKLL-QVTATDADEGTNAVISYDIIGG 678

Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTD 786
           +++ +FS+++  G     + T+  LD+E   + + L+I A    +        V + V +
Sbjct: 679 NNNGNFSIDSSTG----VISTLASLDHE-VEEFFSLIISAKDGGNKYAAKTAVVNVTVLN 733

Query: 787 VNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDKLQYRILSGNNANLILLNET 845
             DN PV       F  Y++  P G   GRV A   D    + Y I+SG+  NL L++ T
Sbjct: 734 KADNLPVFLYEMYNFTVYEN-VPKGTLVGRVYATTKDKNGSISYAIVSGDPTNLFLVDST 792

Query: 846 TGSMTLSPQLN 856
            G + ++  ++
Sbjct: 793 GGIIKINGDMD 803



 Score =  348 bits (855), Expect = 2e-93
 Identities = 258/842 (30%), Positives = 400/842 (47%), Gaps = 64/842 (7%)

Query: 11   INVLDCNDHSPVFEMQQY-----EASVR-EGASSGTTVLTLKATDQDIGKNAEVEYTIEL 64
            INVLD ND+SP  ++        + ++R E +   T +  +  TD+D   N++ E  I  
Sbjct: 301  INVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINTNIAYILVTDKDSNTNSQTELKIT- 359

Query: 65   VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLT-RASLDREKVARYTVLVKATDQA 123
                  N +D            +  F+++      +  +  LDRE V  Y + +  TD+ 
Sbjct: 360  ------NGDD------------EGCFKVEFLGFYFIQLQKPLDRELVPFYNLTLNVTDKG 401

Query: 124  SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183
             P     S+   + +++ D NDN P F+   YT ++ E     +   + ++ ATD D G 
Sbjct: 402  VPSR---STLGFVLIDVTDVNDNSPAFTSNAYTANISE--LAQNGSYVLQLNATDPDEGD 456

Query: 184  NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
            N  + Y+I GGN    F +D  SG V+  K LD EQV S  + I AQD GS  ++ +T +
Sbjct: 457  NGTVSYSITGGNDLGWFQVDFQSGLVTTAKPLDREQVSSVTITITAQDHGSAPKTGSTTV 516

Query: 244  LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
             + I D NDN PRF  S ++ ++SE   IG ++++V A D D G N  +TY ++  D   
Sbjct: 517  TVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEISSSD--A 574

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
             V+    ++ ++G ++T  QLDRET++ Y   V A D GDP   ++              
Sbjct: 575  QVNGLFELNTQTGVLWTKSQLDRETKSLYSFTVLAKDHGDPQLMSSVKVELTISDINDNA 634

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRG 421
              F P +Y   + E+EPPG  ++ +TATDADE     + Y+I GGN  G FSI S    G
Sbjct: 635  PVFYPVEYFASIMENEPPG-KLLQVTATDADEGTNAVISYDIIGGNNNGNFSIDSST--G 691

Query: 422  LITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVF 479
            +I+    LD + E  + L +SA D G +  + TA+V + + +  +  PVF    Y  +V+
Sbjct: 692  VISTLASLDHEVEEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVY 751

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
            E+ P GT V  V AT  D   N  I+Y++   +S +        F+++   G I  N  +
Sbjct: 752  ENVPKGTLVGRVYATTKDK--NGSISYAI---VSGDPT----NLFLVDSTGGIIKINGDM 802

Query: 540  DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
            DRE  + YLL V AR G V  LS    V I V+D NDN P F       +I    LVG  
Sbjct: 803  DREEKAQYLLAVIARVGTVKPLSAQATVNIEVLDRNDNAPQFSTSSVIVDIDGTWLVGQV 862

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
            V    A D D G NG + Y+L      EG   I+  SGVI+  + L       + ++ +A
Sbjct: 863  VYNAAAVDLDAGKNGLVRYQL--TSNAEGLLWINSTSGVIKLARKLTDGDETQYTVQVLA 920

Query: 660  IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
             D G+PPQ ST+ +HI +  IN  PP F       ++  + P+      + A D D G N
Sbjct: 921  SDSGSPPQHSTMTIHITL-SIN-HPPKFTLSSYVTHVLASQPLSYQFFYVVAVDQDSGKN 978

Query: 720  AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWN 776
              + YSI  G++   F +         +L     L  ++ +  Y+L++RA     P    
Sbjct: 979  GQLFYSIPQGNEEGLFGI-----FPGGKLYIRKSL-LQALKGSYDLIVRATDGGVPSFSA 1032

Query: 777  DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY--DADVTDKLQYRILSG 834
             V V I + D ND+  +  +    F   ++  P    G + A+  D   T  + Y ++S 
Sbjct: 1033 SVPVTIYIQDSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYSLISS 1092

Query: 835  NN 836
             +
Sbjct: 1093 ES 1094



 Score =  346 bits (851), Expect = 5e-93
 Identities = 262/878 (29%), Positives = 407/878 (46%), Gaps = 63/878 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I+V D ND+SP F    Y A++ E A +G+ VL L ATD D G N  V Y+I        
Sbjct: 413  IDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSIT------- 465

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
               D               F++D +SG + T   LDRE+V+  T+ + A D  S  + + 
Sbjct: 466  GGNDLGW------------FQVDFQSGLVTTAKPLDREQVSSVTITITAQDHGS--APKT 511

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             ST T+ V IID NDN P+F + +Y  ++ E  S+     + ++ ATD D G N  I Y 
Sbjct: 512  GST-TVTVTIIDGNDNKPRFMKSSYKGTISEGASI--GATVLQVSATDVDSGDNGRITYE 568

Query: 191  IIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            I   + Q+   F +++ +G +     LD E    Y   + A+D G P   ++ ++ + I 
Sbjct: 569  ISSSDAQVNGLFELNTQTGVLWTKSQLDRETKSLYSFTVLAKDHGDPQLMSSVKVELTIS 628

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            D+NDNAP FY   +  S+ EN P G  +++V A DADEG NA ++Y +   +  GN    
Sbjct: 629  DINDNAPVFYPVEYFASIMENEPPG-KLLQVTATDADEGTNAVISYDIIGGNNNGN---- 683

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
             +ID  +G + T   LD E +  + L+++A DGG+   + TA               F+ 
Sbjct: 684  FSIDSSTGVISTLASLDHEVEEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLY 743

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
              Y   + E+ P GT V  + AT  D++  + Y I  G+    F + S  G  +I +   
Sbjct: 744  EMYNFTVYENVPKGTLVGRVYATTKDKNGSISYAIVSGDPTNLFLVDSTGG--IIKINGD 801

Query: 429  LDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
            +D +++ +Y+L V A     +  S  A V I + D N+ AP F  +     +     +G 
Sbjct: 802  MDREEKAQYLLAVIARVGTVKPLSAQATVNIEVLDRNDNAPQFSTSSVIVDIDGTWLVGQ 861

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
             V   +A D D G N  + Y L+S               IN  +G I   + L     + 
Sbjct: 862  VVYNAAAVDLDAGKNGLVRYQLTSNAEG--------LLWINSTSGVIKLARKLTDGDETQ 913

Query: 547  YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
            Y + V A D G P    T  + I++  +N + P F    Y  +++    +      V A 
Sbjct: 914  YTVQVLASDSGSPPQHSTMTIHITL-SIN-HPPKFTLSSYVTHVLASQPLSYQFFYVVAV 971

Query: 607  DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
            D D G NG++ Y + P+  EEG F I P  G +   K+L +    ++DL   A DGG P 
Sbjct: 972  DQDSGKNGQLFYSI-PQGNEEGLFGIFPG-GKLYIRKSLLQALKGSYDLIVRATDGGVPS 1029

Query: 667  QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
             S++V V I I+D ND   +F ++   F ++ENS  GT +G + AH  D      + YS+
Sbjct: 1030 FSASVPVTIYIQDSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYSL 1089

Query: 727  KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY-ELVIRAASPPLWNDVRVE---- 781
               +  + F+++ R G    ++ T V LD E   K     V    +  ++ND  ++    
Sbjct: 1090 ISSE--SHFAVDVRSG----QITTRVRLDREELIKNTGSNVYIMQAEAMYNDTTIKRDKA 1143

Query: 782  ---ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGNN 836
               + VTD+NDNAPV           +   P  P  R+ A DAD  D  K  Y ++SG  
Sbjct: 1144 IVIVTVTDLNDNAPVFSRAVYAITVSELSLPGSPVFRIKAMDADEGDNAKFFYSLVSGTG 1203

Query: 837  ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN 874
             +   +N +TG + LS  L+        + V  TD  N
Sbjct: 1204 MDKFFINSSTGELHLSKTLDRETTSSYNLVVKATDASN 1241



 Score =  344 bits (846), Expect = 2e-92
 Identities = 270/877 (30%), Positives = 413/877 (47%), Gaps = 69/877 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + VL+  D+ PVF  + Y  +V E    GT V  + AT +D  KN  + Y I  V+ D  
Sbjct: 729  VTVLNKADNLPVFLYEMYNFTVYENVPKGTLVGRVYATTKD--KNGSISYAI--VSGDPT 784

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N                 +F +D   G +     +DRE+ A+Y + V A  +   V   L
Sbjct: 785  N-----------------LFLVDSTGGIIKINGDMDREEKAQYLLAVIA--RVGTVKP-L 824

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S+ AT+++ ++D NDN PQFS  T +V VD D +     V+    A D D G N  +RY 
Sbjct: 825  SAQATVNIEVLDRNDNAPQFS--TSSVIVDIDGTWLVGQVVYNAAAVDLDAGKNGLVRYQ 882

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            +   N +    I+S SG + L + L       Y + + A D GSP + +T  + I +  +
Sbjct: 883  LTS-NAEGLLWINSTSGVIKLARKLTDGDETQYTVQVLASDSGSPPQHSTMTIHITL-SI 940

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            N + P+F  S +   V  + P+ Y    V A D D G N +L Y++      GN +    
Sbjct: 941  N-HPPKFTLSSYVTHVLASQPLSYQFFYVVAVDQDSGKNGQLFYSIPQ----GNEEGLFG 995

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            I P  G +Y    L +  +  Y L+V ATDGG P  SA+                F+   
Sbjct: 996  IFP-GGKLYIRKSLLQALKGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRSLFVNNT 1054

Query: 371  YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
            +   +AE+  PGT V TL A   D         +  ++   F++  ++G+  IT    LD
Sbjct: 1055 FRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYSLISSESHFAVDVRSGQ--ITTRVRLD 1112

Query: 431  FKQ------ERRYVLTVSA--TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
             ++         Y++   A   D+  + D A+V + +TD N+ APVF  A Y  +V E +
Sbjct: 1113 REELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVYAITVSELS 1172

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
              G+ V  + A D+D G NA+  YSL S    +       +F IN  TG +  +K LDRE
Sbjct: 1173 LPGSPVFRIKAMDADEGDNAKFFYSLVSGTGMD-------KFFINSSTGELHLSKTLDRE 1225

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
            T S Y L V A D    +L  T  +EI+V D ND  PVF +  YT NI EDAL+G+ V  
Sbjct: 1226 TTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVIN 1285

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
            + A+D D+G NG I Y +         F ++ A+G +   K+LD E+   ++L   A D 
Sbjct: 1286 LNASDKDIGQNGLIKYSIS-NGNLAAMFDVESATGRLIVAKSLDFETTQLYELTITAQDH 1344

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
            G  P SSTV V + + D+ND+ P+F +  +T  + EN   G  +G   A D D G NA +
Sbjct: 1345 GLIPLSSTVNVTVNVLDVNDNAPLFPTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHI 1404

Query: 723  HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE---SPRKKYELVIRA---ASPPLWN 776
             +S+     S +FS+     S   E+ T+  +D E   + R  ++LV+ A    SP L  
Sbjct: 1405 AFSMYSQTPSKTFSV----NSATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLST 1460

Query: 777  DVRVEILVTDVNDNAP-VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGN 835
               + + VTD NDN+P  +        +  +   +         D +   K+ Y I+SGN
Sbjct: 1461 RKSITVQVTDENDNSPGFVSPPAAAAGSSLNVMTI----TAEDPDRNSNGKVTYSIISGN 1516

Query: 836  NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            N     L+ +TG + +  Q+  N P +  + +  +DG
Sbjct: 1517 N-GYFNLHPSTGQLQMIHQIPDN-PTIYQLTIQASDG 1551



 Score =  294 bits (721), Expect = 3e-77
 Identities = 260/919 (28%), Positives = 414/919 (45%), Gaps = 78/919 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ + D ND++PVF   +Y AS+ E    G  +L + ATD D G NA + Y I       
Sbjct: 624  ELTISDINDNAPVFYPVEYFASIMENEPPGK-LLQVTATDADEGTNAVISYDI---IGGN 679

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             N                  F ID  +G + T ASLD E    +++++ A D  +  +  
Sbjct: 680  NNGN----------------FSIDSSTGVISTLASLDHEVEEFFSLIISAKDGGNKYA-- 721

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             + TA ++V +++  DN P F  + Y  +V E+  V    ++ ++ AT  D   N +I Y
Sbjct: 722  -AKTAVVNVTVLNKADNLPVFLYEMYNFTVYEN--VPKGTLVGRVYATTKD--KNGSISY 776

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            AI+ G+    F +DS  G + +   +D E+   Y L + A+ G     S    + I + D
Sbjct: 777  AIVSGDPTNLFLVDSTGGIIKINGDMDREEKAQYLLAVIARVGTVKPLSAQATVNIEVLD 836

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
             NDNAP+F TS     +     +G  +    A D D G N  + Y +T      N +  +
Sbjct: 837  RNDNAPQFSTSSVIVDIDGTWLVGQVVYNAAAVDLDAGKNGLVRYQLTS-----NAEGLL 891

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             I+  SG +  + +L    + +Y + V A+D G PP+ +T T              F   
Sbjct: 892  WINSTSGVIKLARKLTDGDETQYTVQVLASDSGSPPQHSTMTIHITLSINHPPK--FTLS 949

Query: 370  QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
             Y   +   +P       + A D D  ++ +L Y I  GN  G F I      G + + +
Sbjct: 950  SYVTHVLASQPLSYQFFYVVAVDQDSGKNGQLFYSIPQGNEEGLFGIFPG---GKLYIRK 1006

Query: 428  PLDFKQERRYVLTVSATDSGGRSDTAMVQINI--TDANNYAPVFENAPYTASVFEDAPIG 485
             L    +  Y L V ATD G  S +A V + I   D+N++  +F N  +  +V E++  G
Sbjct: 1007 SLLQALKGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRSLFVNNTFRFAVAENSSPG 1066

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM- 544
            T V  + A   D      I YSL   IS+E+       F ++ ++G ITT   LDRE + 
Sbjct: 1067 TLVGTLVAHALDHSRTKDIVYSL---ISSES------HFAVDVRSGQITTRVRLDREELI 1117

Query: 545  -----SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
                 + Y++   A         D   V ++V D+NDN PVF + +Y   + E +L G+ 
Sbjct: 1118 KNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVYAITVSELSLPGSP 1177

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
            V ++ A DAD G N +  Y L      +  F I+ ++G +  +K LDRE+ ++++L   A
Sbjct: 1178 VFRIKAMDADEGDNAKFFYSLVSGTGMD-KFFINSSTGELHLSKTLDRETTSSYNLVVKA 1236

Query: 660  IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
             D       ST  + I + D ND  PVF     T  I+E++ IG+ +  + A D D G N
Sbjct: 1237 TDASNANLYSTAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQN 1296

Query: 720  AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP---PLWN 776
             ++ YSI  G+ +  F +E+  G     L+    LD+E+ +  YEL I A      PL +
Sbjct: 1297 GLIKYSISNGNLAAMFDVESATG----RLIVAKSLDFETTQL-YELTITAQDHGLIPLSS 1351

Query: 777  DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSG 834
             V V + V DVNDNAP+     +     ++     P GR  A D D      + + + S 
Sbjct: 1352 TVNVTVNVLDVNDNAPLFPTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQ 1411

Query: 835  NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLN 894
              +    +N  T  +T    ++     L TM          + A  Q S +L T +    
Sbjct: 1412 TPSKTFSVNSATCEITTIAAID-----LETMPAGRDSFQLVVMATDQGSPKLSTRK---- 1462

Query: 895  SITVRLNDM--TAEQFLSP 911
            SITV++ D    +  F+SP
Sbjct: 1463 SITVQVTDENDNSPGFVSP 1481



 Score =  280 bits (687), Expect = 3e-73
 Identities = 214/699 (30%), Positives = 316/699 (45%), Gaps = 36/699 (5%)

Query: 199 QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY 258
           QF  +S +G +S    +D E      L +R  +   PS +    + + + D+NDN PRF 
Sbjct: 41  QFGFNSNTGVISTTARIDRETTTQISLQLRTLN---PS-NQPISVQVQVDDINDNEPRFP 96

Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW- 317
           T  +   + E++ +  +     A D D G N  + YT+   D T    L  T  P     
Sbjct: 97  TLYYTLRIRESMDVNTTNPINTATDPDAGNNGTVDYTIASGDNTATFSLGTTACPTGSTL 156

Query: 318 -VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376
            V T   LDRET   YQL +TATD G P                     F    Y   +A
Sbjct: 157 CVITKKPLDRETTDFYQLNITATDRGTPALMGYCLINITILDENDHAPVFTQNSYLGSIA 216

Query: 377 EDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434
           E+  PG  ++ ++A D D  +   + Y I     +        +  G+I   Q LDF+ +
Sbjct: 217 ENTKPGVSILRVSAADRDSGSNGDIKYAIDWDAIQSNSIFDLDSSTGVIRTKQNLDFEVK 276

Query: 435 RRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENA---PYT---ASVFEDAPIGT 486
             Y   V A+D G   ++D A V IN+ D N+ +P  +     P+    A   E++ I T
Sbjct: 277 NSYTFNVIASDGGVPSKNDLATVTINVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINT 336

Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
            +  +  TD D   N+Q    +++             F        I   K LDRE +  
Sbjct: 337 NIAYILVTDKDSNTNSQTELKITNGDDEGCFKVEFLGFYF------IQLQKPLDRELVPF 390

Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
           Y LT+   D GVPS S    V I V DVNDN P F    YTANI E A  G+ V Q+ AT
Sbjct: 391 YNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLNAT 450

Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
           D D G NG + Y +   + + G F +D  SG++ T K LDRE V++  +   A D G+ P
Sbjct: 451 DPDEGDNGTVSYSITGGN-DLGWFQVDFQSGLVTTAKPLDREQVSSVTITITAQDHGSAP 509

Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
           ++ +  V + I D ND+ P F        ISE + IG T+ ++ A D D G N  + Y I
Sbjct: 510 KTGSTTVTVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEI 569

Query: 727 KGGDD--SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVE 781
              D   +  F L T+ G     L T   LD E+ +  Y   + A     P L + V+VE
Sbjct: 570 SSSDAQVNGLFELNTQTGV----LWTKSQLDRET-KSLYSFTVLAKDHGDPQLMSSVKVE 624

Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANL 839
           + ++D+NDNAPV    +  F +  +  P G   +V A DAD      + Y I+ GNN   
Sbjct: 625 LTISDINDNAPVFYPVEY-FASIMENEPPGKLLQVTATDADEGTNAVISYDIIGGNNNGN 683

Query: 840 ILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKA 878
             ++ +TG ++    L+  V +  ++ +S  DG N+  A
Sbjct: 684 FSIDSSTGVISTLASLDHEVEEFFSLIISAKDGGNKYAA 722



 Score =  252 bits (616), Expect = 1e-64
 Identities = 200/692 (28%), Positives = 325/692 (46%), Gaps = 59/692 (8%)

Query: 2    SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
            SVP  I+ Q    D NDH  +F    +  +V E +S GT V TL A   D  +  ++ Y+
Sbjct: 1033 SVPVTIYIQ----DSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYS 1088

Query: 62   IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYT---VLVK 118
              L+++++                    F +D RSG + TR  LDRE++ + T   V + 
Sbjct: 1089 --LISSESH-------------------FAVDVRSGQITTRVRLDREELIKNTGSNVYIM 1127

Query: 119  ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178
              +     +      A + V + D NDN P FS   Y ++V E +S+  +PV  +IKA D
Sbjct: 1128 QAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVYAITVSE-LSLPGSPVF-RIKAMD 1185

Query: 179  ADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238
            AD G N+   Y+++ G    +F I+S +G++ L KTLD E   SY LV++A D  + +  
Sbjct: 1186 ADEGDNAKFFYSLVSGTGMDKFFINSSTGELHLSKTLDRETTSSYNLVVKATDASNANLY 1245

Query: 239  NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
            +T ++ I + D ND  P F  S +  +++E+  IG  ++ + A D D G N  + Y++++
Sbjct: 1246 STAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYSISN 1305

Query: 299  KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358
                GN+     ++  +G +  +  LD ET   Y+L +TA D G  P S+T         
Sbjct: 1306 ----GNLAAMFDVESATGRLIVAKSLDFETTQLYELTITAQDHGLIPLSSTVNVTVNVLD 1361

Query: 359  XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITS 416
                   F      + + E+   G PV   TA+D D     H  + +        FS+ S
Sbjct: 1362 VNDNAPLFPTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQTPSKTFSVNS 1421

Query: 417  QNGRGLITVAQPLDFKQERR--YVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENA 472
                     A  L+     R  + L V ATD G    S    + + +TD N+ +P F + 
Sbjct: 1422 ATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGFVSP 1481

Query: 473  PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
            P  A     A     V+ ++A D D   N ++TYS+        ++ ++  F ++P TG 
Sbjct: 1482 PAAA-----AGSSLNVMTITAEDPDRNSNGKVTYSI--------ISGNNGYFNLHPSTGQ 1528

Query: 533  ITT-NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
            +   +++ D  T+  Y LT+ A DGG PS    T V +         P F    Y  ++ 
Sbjct: 1529 LQMIHQIPDNPTI--YQLTIQASDGGQPSRQTQTVVSVFKEGPIGGGPTFSSADYQGSVT 1586

Query: 592  EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV- 650
            E+ + GTSV  V A      LNG I Y L   D  +G F +  ++GV++T + +DRE + 
Sbjct: 1587 ENKVAGTSVVTVLAAYPQSSLNGNIEYYL-TSDSSKGGFEVVKSTGVVKTTRGIDREGMG 1645

Query: 651  ATHDLKAVAID-GGTPPQSSTVIVHIKIEDIN 681
            A+ +L   A+D  G   ++S+  V I ++D+N
Sbjct: 1646 ASFNLVVYAVDKQGPSARTSSATVTITVQDVN 1677



 Score =  244 bits (596), Expect = 4e-62
 Identities = 218/789 (27%), Positives = 345/789 (43%), Gaps = 70/789 (8%)

Query: 18   DHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXX 77
            +H P F +  Y   V            + A DQD GKN ++ Y+I         P+    
Sbjct: 941  NHPPKFTLSSYVTHVLASQPLSYQFFYVVAVDQDSGKNGQLFYSI---------PQGNE- 990

Query: 78   XXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIH 137
                     + +F I    G L  R SL +     Y ++V+ATD   P     S++  + 
Sbjct: 991  ---------EGLFGIFP-GGKLYIRKSLLQALKGSYDLIVRATDGGVP---SFSASVPVT 1037

Query: 138  VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQ 197
            + I D ND+   F   T+  +V E+ S     ++  + A   D      I Y++I  +++
Sbjct: 1038 IYIQDSNDHRSLFVNNTFRFAVAENSS--PGTLVGTLVAHALDHSRTKDIVYSLI--SSE 1093

Query: 198  MQFSIDSLSGDVSLVKTLDYEQV------RSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251
              F++D  SG ++    LD E++        Y +   A    +  + +   +++ + D+N
Sbjct: 1094 SHFAVDVRSGQITTRVRLDREELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLN 1153

Query: 252  DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311
            DNAP F  +++  +VSE    G  + R++A DADEG NA+  Y++     TG +D    I
Sbjct: 1154 DNAPVFSRAVYAITVSELSLPGSPVFRIKAMDADEGDNAKFFYSLVSG--TG-MD-KFFI 1209

Query: 312  DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371
            +  +G ++ S  LDRET + Y L+V ATD  +    +TA               F    Y
Sbjct: 1210 NSSTGELHLSKTLDRETTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVFPESDY 1269

Query: 372  EVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
             V + ED   G+ V+ L A+D D  ++  + Y I+ GN    F + S  GR  + VA+ L
Sbjct: 1270 TVNITEDALIGSLVINLNASDKDIGQNGLIKYSISNGNLAAMFDVESATGR--LIVAKSL 1327

Query: 430  DFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
            DF+  + Y LT++A D G    S T  V +N+ D N+ AP+F   P T +V E+   G  
Sbjct: 1328 DFETTQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAPLFPTQPVTLTVRENVNTGFP 1387

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM--- 544
            V   +A+D D G NA I +S+ S+  ++        F +N  T  ITT   +D ETM   
Sbjct: 1388 VGRCTASDRDTGTNAHIAFSMYSQTPSKT-------FSVNSATCEITTIAAIDLETMPAG 1440

Query: 545  -SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
               + L V A D G P LS    + + V D NDN P F      A     A    +V  +
Sbjct: 1441 RDSFQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGFVSPPAAA-----AGSSLNVMTI 1495

Query: 604  GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
             A D D   NG++ Y +   +   G F + P++G ++    +  ++   + L   A DGG
Sbjct: 1496 TAEDPDRNSNGKVTYSIISGNN--GYFNLHPSTGQLQMIHQIP-DNPTIYQLTIQASDGG 1552

Query: 664  TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
             P + +  +V +  E      P F S      ++EN   GT++  + A  P    N  + 
Sbjct: 1553 QPSRQTQTVVSVFKEGPIGGGPTFSSADYQGSVTENKVAGTSVVTVLAAYPQSSLNGNIE 1612

Query: 724  YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS----PPLWNDVR 779
            Y +        F +    G  K    T   +D E     + LV+ A          +   
Sbjct: 1613 YYLTSDSSKGGFEVVKSTGVVK----TTRGIDREGMGASFNLVVYAVDKQGPSARTSSAT 1668

Query: 780  VEILVTDVN 788
            V I V DVN
Sbjct: 1669 VTITVQDVN 1677



 Score =  172 bits (418), Expect = 1e-40
 Identities = 147/512 (28%), Positives = 224/512 (43%), Gaps = 30/512 (5%)

Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
           Y   + E++PPGT V  +    A E          G+ + +F   S    G+I+    +D
Sbjct: 12  YTFHVQEEQPPGTYVGKVDGASAFE----------GSPK-QFGFNSNT--GVISTTARID 58

Query: 431 FKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
             +E    +++        +    VQ+ + D N+  P F    YT  + E   + TT  +
Sbjct: 59  --RETTTQISLQLRTLNPSNQPISVQVQVDDINDNEPRFPTLYYTLRIRESMDVNTTNPI 116

Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550
            +ATD D G N  + Y+++S   N A             T  + T K LDRET   Y L 
Sbjct: 117 NTATDPDAGNNGTVDYTIASG-DNTATFSLGTTACPTGSTLCVITKKPLDRETTDFYQLN 175

Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610
           +TA D G P+L     + I+++D ND+ PVF Q  Y  +I E+   G S+ +V A D D 
Sbjct: 176 ITATDRGTPALMGYCLINITILDENDHAPVFTQNSYLGSIAENTKPGVSILRVSAADRDS 235

Query: 611 GLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669
           G NG I Y +D    +  S F +D ++GVIRT + LD E   ++    +A DGG P ++ 
Sbjct: 236 GSNGDIKYAIDWDAIQSNSIFDLDSSTGVIRTKQNLDFEVKNSYTFNVIASDGGVPSKND 295

Query: 670 TVIVHIKIEDINDSPPVFESDCLTFY------ISENSPIGTTIGEIRAHDPDEGPNAVVH 723
              V I + D ND+ P  +   L  +       SENS I T I  I   D D   N+   
Sbjct: 296 LATVTINVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINTNIAYILVTDKDSNTNSQTE 355

Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR-VEI 782
             I  GDD   F +E   G    +L   +D +   P     L +     P  + +  V I
Sbjct: 356 LKITNGDDEGCFKVEF-LGFYFIQLQKPLDREL-VPFYNLTLNVTDKGVPSRSTLGFVLI 413

Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVTDK--LQYRILSGNNANL 839
            VTDVNDN+P          N  +    G +  ++ A D D  D   + Y I  GN+   
Sbjct: 414 DVTDVNDNSPAFTS-NAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSITGGNDLGW 472

Query: 840 ILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
             ++  +G +T +  L+       T+ ++  D
Sbjct: 473 FQVDFQSGLVTTAKPLDREQVSSVTITITAQD 504


>UniRef50_UPI00006A0F33 Cluster: dachsous 2 isoform 1; n=1; Xenopus
            tropicalis|Rep: dachsous 2 isoform 1 - Xenopus tropicalis
          Length = 2787

 Score =  372 bits (914), Expect = e-100
 Identities = 272/902 (30%), Positives = 436/902 (48%), Gaps = 63/902 (6%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++++ D ND+ P+F    + A + E    G ++ ++ A+D D G NA++ Y+I  +    
Sbjct: 1308 KLDISDVNDNPPMFVKSTFVAYLPENNLPGASIYSIHASDPDYGNNAKIIYSISNIVGTV 1367

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                D+                  GR   ++T+++LDREK A Y + + ATD+ SP   +
Sbjct: 1368 PFQLDSST----------------GRFYRIVTKSALDREKTALYNITIVATDKGSP---Q 1408

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            LSS   I ++I D NDN P F +      + E+     +  I +I+A+D D G N+ + Y
Sbjct: 1409 LSSRKFIRLDISDVNDNPPVFMKSKDVAYLPENNLPGSS--IYRIQASDLDTGDNAKVIY 1466

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            +I   + +  F I S    + L K LD E    + L++ A DGG+P RS T  + I + D
Sbjct: 1467 SISSMDNE-DFPISSYFSKLVLEKPLDRETQTIHELILTASDGGNPVRSGTALIRIAVTD 1525

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
             NDN P F   +++ S+SEN+PI  +++ V A D DEG NA++ Y+     ++ N++   
Sbjct: 1526 SNDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQIMYSFRSSFFSINIE--- 1582

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM-P 368
                 +G +Y     D E   ++Q+ V A D G P  S  A+               + P
Sbjct: 1583 -----TGVLYAQRSFDYEQHKEFQIKVYAKDYGSPSLSCNASLTIRITDQNDNVPKILYP 1637

Query: 369  GQYEVELAEDEPP-----GTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRG 421
                V+ + +  P     G  +  + A DAD  +   L Y +  G+    FSI SQN   
Sbjct: 1638 SSESVDSSFEMVPVASEQGALITKVVAVDADSGHNAWLSYHVVQGSEPSLFSI-SQNTGE 1696

Query: 422  LITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVF 479
            + T  +PLD + +  + L ++A+D G   RS TA+++I +TDAN+  PVF    Y  S+ 
Sbjct: 1697 IRTSQKPLDRETQTIHELILTASDGGNPVRSGTALIRIAVTDANDNLPVFTQEVYKVSIT 1756

Query: 480  ---EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
               ED+P GT + ++   D D G N +I   L      + +    + + I      ITT 
Sbjct: 1757 IIPEDSPSGTLIALIEVHDQDSGENGEIDCQLLGTGPFQLLLSSTKYYRI------ITTG 1810

Query: 537  KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
              LDRE +  Y +T+ A D G P LS+   +++ + DVNDN PVF +  Y A I E+ L 
Sbjct: 1811 S-LDREKVPWYNITIQATDRGSPHLSNIKLIKLDISDVNDNAPVFTKSSYVAYIAENNLA 1869

Query: 597  GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN-KALDRESVATHDL 655
            G S+ ++ A+D D G N +I Y +   + E   F I   +G IR++ K LDRE+   H+L
Sbjct: 1870 GASIYRIQASDIDAGDNAKIIYSI--YNTEPSPFSISQHTGEIRSSQKPLDRETQKDHEL 1927

Query: 656  KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
               A DGG P ++ T I+ I + D ND+ PVF        ISEN PI +++  + A D D
Sbjct: 1928 ILTASDGGDPVKTGTAIIRIIVTDANDNLPVFTKAVYKVSISENIPINSSVLHVNATDRD 1987

Query: 716  EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW 775
            EG NA + YS     +++  S          E+ T+  LD+E  R  YE+ ++A     +
Sbjct: 1988 EGTNAQITYSFIKTSENDIHSPMFSINQINGEIKTLQKLDFELTR-NYEMSVQATDGGGF 2046

Query: 776  NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILS 833
                + + ++DVNDN PV    + I    ++  P     +V A D D     K+ Y + +
Sbjct: 2047 VAKSILLDISDVNDNPPVFLKSRYIAYLPENNLPGASIYKVQASDLDTGENSKVIYSVFN 2106

Query: 834  GNN-----ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLI 887
             N      ++   +N  TG +      +    K   M V   D G   + +   L +R+I
Sbjct: 2107 TNTEAFPVSSYFSINIETGVLYAQRSFDYEQHKEFAMHVQAKDNGYPSLSSNATLIIRII 2166

Query: 888  TE 889
             +
Sbjct: 2167 DQ 2168



 Score =  363 bits (893), Expect = 4e-98
 Identities = 275/881 (31%), Positives = 427/881 (48%), Gaps = 76/881 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I V D ND+ PVF    Y+ S+ E     ++VL + ATD+D G NA++ Y+    + + 
Sbjct: 1946 RIIVTDANDNLPVFTKAVYKVSISENIPINSSVLHVNATDRDEGTNAQITYSFIKTSEND 2005

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            ++                 +F I+  +G + T   LD E    Y + V+ATD    V+  
Sbjct: 2006 IH---------------SPMFSINQINGEIKTLQKLDFELTRNYEMSVQATDGGGFVAK- 2049

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
                 +I ++I D NDN P F +  Y   + E+        I K++A+D D G NS + Y
Sbjct: 2050 -----SILLDISDVNDNPPVFLKSRYIAYLPENN--LPGASIYKVQASDLDTGENSKVIY 2102

Query: 190  AIIGGNTQM-----QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
            ++   NT+       FSI+  +G +   ++ DYEQ + + + ++A+D G PS S+   L+
Sbjct: 2103 SVFNTNTEAFPVSSYFSINIETGVLYAQRSFDYEQHKEFAMHVQAKDNGYPSLSSNATLI 2162

Query: 245  INIRDVNDNAPRFYTSLFQESVS---ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
            I I D NDNAP+      + S S   E VP   +     A D D G N+  TY ++D  Y
Sbjct: 2163 IRIIDQNDNAPKILYPSTENSDSLIFEMVPFAST-----AEDPDIGSNSVQTYKLSDNQY 2217

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
                +   +   +   +     LDRET+  ++LL+TA+DGG P R+ TA           
Sbjct: 2218 FTLNEKTSSDGSKFPELVLERPLDRETKNIHELLLTASDGGTPVRTGTALIRVIVTDAND 2277

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421
                F    Y+V ++E+ P  + V+ + A+D DE        +   T   FS+  +NG  
Sbjct: 2278 NTPVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSKYFSVDLENGNL 2337

Query: 422  L-ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASV 478
              + + +PLD + +  + L ++A+D G   R+ TA++++ +TDAN+  PVF    Y  S+
Sbjct: 2338 YELVLERPLDREIKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSI 2397

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA------ 532
             E+ PI +TVL V+A+D D G NAQITYS S    N     H   F INP +G       
Sbjct: 2398 SENTPINSTVLRVNASDMDEGTNAQITYSFSRTSENSL---HASMFSINPTSGEMNEKTS 2454

Query: 533  --------ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584
                    +   + LDRET + + L +TA DGG P  + T  + + V D NDN PVF Q+
Sbjct: 2455 SDGSKFPELVLERPLDRETKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQE 2514

Query: 585  LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP---KDREEGSFVIDPASGVIRT 641
            +Y  +I E+  + ++V +V A+D D G N +I Y              F I+P SG I T
Sbjct: 2515 VYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEITT 2574

Query: 642  NKALDRESVATHDLKAVAIDGGTPPQSSTVI-VHIKIEDINDSPPVFESDCLTFYISENS 700
            N  L+ E+   +++   A DGG     S V  V I+I+DIND+ P F     T  ISEN+
Sbjct: 2575 NNLLNFEAKKDYEISVQAKDGGGFVAHSKVFPVIIEIQDINDNAPKFFPVLYTVSISENT 2634

Query: 701  PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760
             +G+ +  + A D DEG NA + YS     +S+             E+ T   L++E  R
Sbjct: 2635 AVGSVVLCVNATDKDEGINAQITYSFSKTSESSLNKSMFSINPTTGEIKTEKQLNFEGTR 2694

Query: 761  KKYELVIRAASPPLW-NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY 819
              YEL ++A     +    +V I +TD NDNAP +    +     +D  P      +  +
Sbjct: 2695 N-YELSVQAKDGGGFVTHSKVLIEITDENDNAPEISIASLSTPVPEDSAPGSVIALIEVH 2753

Query: 820  DADVTDKLQYRILSGNNANLIL-LNETTGSMTLSPQLNTNV 859
            D D          SG+NA +   ++ET    T+SP  + N+
Sbjct: 2754 DQD----------SGSNAKITYSISETN---TMSPYFSINI 2781



 Score =  359 bits (884), Expect = 5e-97
 Identities = 266/909 (29%), Positives = 439/909 (48%), Gaps = 82/909 (9%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I + D NDH P+F  + Y+ S+ E     TTVL + ATD+D G NA++ Y++   + D+
Sbjct: 861  RIAITDVNDHIPMFTQEVYKVSISESIPINTTVLQVNATDKDEGVNAQITYSLIRTSGDS 920

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD- 128
            L                   F I+  SG + T+ +L+ E    Y + V+A D A+   + 
Sbjct: 921  L---------------ASATFSINPASGEIKTKRNLNFEVQKHYEMSVEAKDGATDGGNP 965

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            + + TA + + + D NDN P F+++ Y +S+ E   +  N  +  + ATD D G N  I 
Sbjct: 966  KRTGTALLRIIVTDYNDNVPVFTQQVYKISISESAPI--NSTVTVVTATDKDDGTNGHIT 1023

Query: 189  YAII-----GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
            Y+         +TQM F+I+  +G++   ++ DYEQ + +++ I A+D GSP  S+   L
Sbjct: 1024 YSFSRTAENAFHTQM-FNINPANGEIKTKRSFDYEQHKEFQINIMAKDNGSPPLSSNATL 1082

Query: 244  LINIRDVNDNAPRFYTSLFQESVS---ENVPI----GYSIVRVQAYDADEGVNAELTYTM 296
            +I+I D NDNAP+      +   S   E VP     G  I ++ A D D G NA++ Y++
Sbjct: 1083 IIHIIDQNDNAPKILYPSTESGGSPFFEMVPFASVQGSLITKIHASDPDAGDNAKIIYSI 1142

Query: 297  TDKDYTGNVDLPI----TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT- 351
            ++       D P+    +I+  +G +Y     D E   ++Q+ ++A D G PP S+  T 
Sbjct: 1143 SN---INTEDFPVSPYFSINIETGVLYAQRSFDYEQHKEFQMKISAKDNGSPPLSSNVTL 1199

Query: 352  --XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGN 407
                                       ED  PGT +  +   D D  E+  +  +I G +
Sbjct: 1200 IIHIIEIMDENDNAPEISIRSLSTPFPEDSAPGTLIALIEVHDQDSGENGEVECQIIGPS 1259

Query: 408  TRGRFSITSQNGRGL-ITVAQPLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANN 464
                F + S + R   I     LD +    Y +T+ ATD G    + M  ++++I+D N+
Sbjct: 1260 P---FQLLSSSSRYYKIVNTGSLDRELVPWYNITILATDRGSPQLSTMKFIKLDISDVND 1316

Query: 465  YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524
              P+F  + + A + E+   G ++  + A+D D G NA+I YS+S+ +           F
Sbjct: 1317 NPPMFVKSTFVAYLPENNLPGASIYSIHASDPDYGNNAKIIYSISNIVGT-------VPF 1369

Query: 525  VINPQTG---AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581
             ++  TG    I T   LDRE  + Y +T+ A D G P LS    + + + DVNDN PVF
Sbjct: 1370 QLDSSTGRFYRIVTKSALDREKTALYNITIVATDKGSPQLSSRKFIRLDISDVNDNPPVF 1429

Query: 582  KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641
             +    A + E+ L G+S+ ++ A+D D G N ++ Y +   D E+  F I      +  
Sbjct: 1430 MKSKDVAYLPENNLPGSSIYRIQASDLDTGDNAKVIYSISSMDNED--FPISSYFSKLVL 1487

Query: 642  NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701
             K LDRE+   H+L   A DGG P +S T ++ I + D ND+ PVF  +     ISEN P
Sbjct: 1488 EKPLDRETQTIHELILTASDGGNPVRSGTALIRIAVTDSNDNLPVFTQEVYKVSISENIP 1547

Query: 702  IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761
            I +T+  + A D DEG NA + YS +    S+ FS+    G     L      DYE   K
Sbjct: 1548 INSTVLTVNATDRDEGTNAQIMYSFR----SSFFSINIETG----VLYAQRSFDYEQ-HK 1598

Query: 762  KYELVIRA---ASPPLWNDVRVEILVTDVNDNAP-VMKDFQIIFNNYKDCFPVGP----- 812
            ++++ + A    SP L  +  + I +TD NDN P ++       ++  +  PV       
Sbjct: 1599 EFQIKVYAKDYGSPSLSCNASLTIRITDQNDNVPKILYPSSESVDSSFEMVPVASEQGAL 1658

Query: 813  FGRVPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTLSPQ-LNTNVPKLATMEVSV 869
              +V A DAD      L Y ++ G+  +L  +++ TG +  S + L+     +  + ++ 
Sbjct: 1659 ITKVVAVDADSGHNAWLSYHVVQGSEPSLFSISQNTGEIRTSQKPLDRETQTIHELILTA 1718

Query: 870  TDGVNEIKA 878
            +DG N +++
Sbjct: 1719 SDGGNPVRS 1727



 Score =  356 bits (875), Expect = 6e-96
 Identities = 276/907 (30%), Positives = 447/907 (49%), Gaps = 88/907 (9%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVR---EGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            +I V D ND+ PVF  + Y+ S+    E + SGT +  ++  DQD G+N E++  + L T
Sbjct: 1733 RIAVTDANDNLPVFTQEVYKVSITIIPEDSPSGTLIALIEVHDQDSGENGEIDCQL-LGT 1791

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
                 P                 +RI       +T  SLDREKV  Y + ++ATD+ SP 
Sbjct: 1792 G----PFQLLLSSTKY-------YRI-------ITTGSLDREKVPWYNITIQATDRGSP- 1832

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
               LS+   I ++I D NDN P F++ +Y   + E+     +  I +I+A+D D G N+ 
Sbjct: 1833 --HLSNIKLIKLDISDVNDNAPVFTKSSYVAYIAENNLAGAS--IYRIQASDIDAGDNAK 1888

Query: 187  IRYAIIGGNTQMQ-FSIDSLSGDV-SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
            I Y+I   NT+   FSI   +G++ S  K LD E  + + L++ A DGG P ++ T  + 
Sbjct: 1889 IIYSIY--NTEPSPFSISQHTGEIRSSQKPLDRETQKDHELILTASDGGDPVKTGTAIIR 1946

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
            I + D NDN P F  ++++ S+SEN+PI  S++ V A D DEG NA++TY+   K    +
Sbjct: 1947 IIVTDANDNLPVFTKAVYKVSISENIPINSSVLHVNATDRDEGTNAQITYSFI-KTSEND 2005

Query: 305  VDLPI-TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
            +  P+ +I+  +G + T  +LD E    Y++ V ATDGG        +            
Sbjct: 2006 IHSPMFSINQINGEIKTLQKLDFELTRNYEMSVQATDGGG---FVAKSILLDISDVNDNP 2062

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG-- 419
              F+  +Y   L E+  PG  +  + A+D D  E++++ Y +   NT   F ++S     
Sbjct: 2063 PVFLKSRYIAYLPENNLPGASIYKVQASDLDTGENSKVIYSVFNTNTEA-FPVSSYFSIN 2121

Query: 420  --RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAP--VFENAP 473
               G++   +  D++Q + + + V A D+G    S  A + I I D N+ AP  ++ +  
Sbjct: 2122 IETGVLYAQRSFDYEQHKEFAMHVQAKDNGYPSLSSNATLIIRIIDQNDNAPKILYPSTE 2181

Query: 474  YTAS-VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
             + S +FE  P  +T     A D D+G N+  TY LS    N+    +++      +   
Sbjct: 2182 NSDSLIFEMVPFAST-----AEDPDIGSNSVQTYKLSD---NQYFTLNEKTSSDGSKFPE 2233

Query: 533  ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592
            +   + LDRET + + L +TA DGG P  + T  + + V D NDN PVF Q++Y  +I E
Sbjct: 2234 LVLERPLDRETKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISE 2293

Query: 593  DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT---NKALDRES 649
            +  + ++V +V A+D D G N +I Y      R    F +D  +G +      + LDRE 
Sbjct: 2294 NTPINSTVLRVNASDMDEGTNAQITYSFS---RTSKYFSVDLENGNLYELVLERPLDREI 2350

Query: 650  VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
               H+L   A DGGTP ++ T ++ + + D ND+ PVF  +     ISEN+PI +T+  +
Sbjct: 2351 KNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISENTPINSTVLRV 2410

Query: 710  RAHDPDEGPNAVVHYSIKGGDDSN----SFSLE----------TRQGSDKAELVTMVDLD 755
             A D DEG NA + YS     +++     FS+           +  GS   ELV    LD
Sbjct: 2411 NASDMDEGTNAQITYSFSRTSENSLHASMFSINPTSGEMNEKTSSDGSKFPELVLERPLD 2470

Query: 756  YESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-G 811
             E+ +  +EL++ A+   +P       + ++VTD NDN PV    ++   +  +  P+  
Sbjct: 2471 RET-KNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQ-EVYKVSISENTPINS 2528

Query: 812  PFGRVPAYDAD------VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATM 865
               RV A D D      +T       ++  +A++  +N T+G +T +  LN    K   +
Sbjct: 2529 TVLRVNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEITTNNLLNFEAKKDYEI 2588

Query: 866  EVSVTDG 872
             V   DG
Sbjct: 2589 SVQAKDG 2595



 Score =  354 bits (871), Expect = 2e-95
 Identities = 260/867 (29%), Positives = 410/867 (47%), Gaps = 59/867 (6%)

Query: 12   NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71
            +V D ND+ P+F  + Y  S+ E    G+ +  + A+D+D GKNA++ Y           
Sbjct: 334  SVDDINDNPPLFTEELYFFSIAENILPGSLIFQVSASDKDSGKNAQLLY----------- 382

Query: 72   PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131
               A          V     I+  SG + +  S D EK+ +  + V  TD  +P    LS
Sbjct: 383  ---ALLESYVEGMSVSHFISINPDSGNVFSVDSFDYEKIPQKNITVTVTDSGTPP---LS 436

Query: 132  STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191
            +  T++V + D NDN P F EK+Y++ + E+ +      +  +KATD D   NS + Y++
Sbjct: 437  TQKTLYVEVSDLNDNPPTFEEKSYSIYIMENNA--PGVSLISVKATDLDSNENSFVSYSL 494

Query: 192  IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251
            +  +    F ++  +G++     LD E    Y + I + D GSP  S    + +NI DVN
Sbjct: 495  LRASDPKLFQVELHTGEIRTTSFLDRENTSQYNITILSTDRGSPKLSTVKHIRLNISDVN 554

Query: 252  DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311
            DNAP F  S +   +SEN   G SI R+ AYD D G NA++ Y++       N+     I
Sbjct: 555  DNAPIFKKSTYVAYLSENNLPGSSIYRINAYDPDTGDNAKIIYSIAGT----NIKSTFDI 610

Query: 312  DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371
            +P SG + T   LD E+   Y++ + A DGG     A                       
Sbjct: 611  NPTSGKITTKRDLDFESVQSYEIAIEAMDGGG--FVAQTKVLIEIIDENDNAPEISIASL 668

Query: 372  EVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGL-ITVAQP 428
               + ED  PGT +  +   D D   +  +  +I G      F I S + R   I  A  
Sbjct: 669  SAPIPEDSMPGTVIALIKVHDQDTGRNGEVDCQILGA---APFQIVSSSSRYYRIITASF 725

Query: 429  LDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
            LD ++   Y +T+ ATD G    S T  ++++++D N+  PVF    Y A + E+   G+
Sbjct: 726  LDREKVPWYNITILATDKGSPELSSTKSIKLDLSDVNDNPPVFSKPTYVAYLPENNLPGS 785

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG--AITTNKLLDRETM 544
            ++  + A D D G NA++ YS+        +      F IN  TG   +   K LDRE +
Sbjct: 786  SIYRIQAFDFDSGNNAKVVYSI--------LMSDPSPFSINQYTGEHKVVIMKPLDRENL 837

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
              + L +TA DGG P  + T  + I++ DVND+ P+F Q++Y  +I E   + T+V QV 
Sbjct: 838  KIHKLLLTAFDGGNPVRTGTALIRIAITDVNDHIPMFTQEVYKVSISESIPINTTVLQVN 897

Query: 605  ATDADVGLNGRIHYEL---DPKDREEGSFVIDPASGVIRTNKALDRESVATHDL----KA 657
            ATD D G+N +I Y L           +F I+PASG I+T + L+ E    +++    K 
Sbjct: 898  ATDKDEGVNAQITYSLIRTSGDSLASATFSINPASGEIKTKRNLNFEVQKHYEMSVEAKD 957

Query: 658  VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
             A DGG P ++ T ++ I + D ND+ PVF        ISE++PI +T+  + A D D+G
Sbjct: 958  GATDGGNPKRTGTALLRIIVTDYNDNVPVFTQQVYKISISESAPINSTVTVVTATDKDDG 1017

Query: 718  PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPL 774
             N  + YS     ++   +          E+ T    DYE   K++++ I A    SPPL
Sbjct: 1018 TNGHITYSFSRTAENAFHTQMFNINPANGEIKTKRSFDYEQ-HKEFQINIMAKDNGSPPL 1076

Query: 775  WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSG 834
             ++  + I + D NDNAP +  +    +     F + PF  V    + +T        +G
Sbjct: 1077 SSNATLIIHIIDQNDNAPKIL-YPSTESGGSPFFEMVPFASVQG--SLITKIHASDPDAG 1133

Query: 835  NNANLI--LLNETTGSMTLSPQLNTNV 859
            +NA +I  + N  T    +SP  + N+
Sbjct: 1134 DNAKIIYSISNINTEDFPVSPYFSINI 1160



 Score =  353 bits (869), Expect = 3e-95
 Identities = 261/897 (29%), Positives = 433/897 (48%), Gaps = 62/897 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I ++D ND++P   +    A + E +  GT +  +K  DQD G+N EV+  I        
Sbjct: 651  IEIIDENDNAPEISIASLSAPIPEDSMPGTVIALIKVHDQDTGRNGEVDCQI-------- 702

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                              +     R   ++T + LDREKV  Y + + ATD+ SP    L
Sbjct: 703  -----------LGAAPFQIVSSSSRYYRIITASFLDREKVPWYNITILATDKGSP---EL 748

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            SST +I +++ D NDN P FS+ TY   + E+     +  I +I+A D D G N+ + Y+
Sbjct: 749  SSTKSIKLDLSDVNDNPPVFSKPTYVAYLPENNLPGSS--IYRIQAFDFDSGNNAKVVYS 806

Query: 191  IIGGNTQMQFSIDSLSGD--VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            I+  +    FSI+  +G+  V ++K LD E ++ ++L++ A DGG+P R+ T  + I I 
Sbjct: 807  ILMSDPS-PFSINQYTGEHKVVIMKPLDRENLKIHKLLLTAFDGGNPVRTGTALIRIAIT 865

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            DVND+ P F   +++ S+SE++PI  ++++V A D DEGVNA++TY++            
Sbjct: 866  DVNDHIPMFTQEVYKVSISESIPINTTVLQVNATDKDEGVNAQITYSLIRTSGDSLASAT 925

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVT----ATDGGDPPRSATATXXXXXXXXXXXXX 364
             +I+P SG + T   L+ E Q  Y++ V     ATDGG+P R+ TA              
Sbjct: 926  FSINPASGEIKTKRNLNFEVQKHYEMSVEAKDGATDGGNPKRTGTALLRIIVTDYNDNVP 985

Query: 365  XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGR------FSITSQN 418
             F    Y++ ++E  P  + V  +TATD D+    H   +   T         F+I   N
Sbjct: 986  VFTQQVYKISISESAPINSTVTVVTATDKDDGTNGHITYSFSRTAENAFHTQMFNINPAN 1045

Query: 419  GRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAP--VFENAPY 474
            G   I   +  D++Q + + + + A D+G    S  A + I+I D N+ AP  ++ +   
Sbjct: 1046 GE--IKTKRSFDYEQHKEFQINIMAKDNGSPPLSSNATLIIHIIDQNDNAPKILYPSTES 1103

Query: 475  TAS-VFEDAPI----GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
              S  FE  P     G+ +  + A+D D G NA+I YS+S+ I+ E        F IN +
Sbjct: 1104 GGSPFFEMVPFASVQGSLITKIHASDPDAGDNAKIIYSISN-INTEDFP-VSPYFSINIE 1161

Query: 530  TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV---NDNEPVFKQQLY 586
            TG +   +  D E    + + ++A+D G P LS    + I ++++   NDN P    +  
Sbjct: 1162 TGVLYAQRSFDYEQHKEFQMKISAKDNGSPPLSSNVTLIIHIIEIMDENDNAPEISIRSL 1221

Query: 587  TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646
            +    ED+  GT ++ +   D D G NG +  ++      +          ++ T  +LD
Sbjct: 1222 STPFPEDSAPGTLIALIEVHDQDSGENGEVECQIIGPSPFQLLSSSSRYYKIVNTG-SLD 1280

Query: 647  RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706
            RE V  +++  +A D G+P  S+   + + I D+ND+PP+F       Y+ EN+  G +I
Sbjct: 1281 RELVPWYNITILATDRGSPQLSTMKFIKLDISDVNDNPPMFVKSTFVAYLPENNLPGASI 1340

Query: 707  GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV 766
              I A DPD G NA + YSI     +  F L++  G     +VT   LD E     Y + 
Sbjct: 1341 YSIHASDPDYGNNAKIIYSISNIVGTVPFQLDSSTGR-FYRIVTKSALDREK-TALYNIT 1398

Query: 767  IRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV 823
            I A    SP L +   + + ++DVNDN PV    + +    ++  P     R+ A D D 
Sbjct: 1399 IVATDKGSPQLSSRKFIRLDISDVNDNPPVFMKSKDVAYLPENNLPGSSIYRIQASDLDT 1458

Query: 824  TD--KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKA 878
             D  K+ Y I S +N +   ++     + L   L+     +  + ++ +DG N +++
Sbjct: 1459 GDNAKVIYSISSMDNED-FPISSYFSKLVLEKPLDRETQTIHELILTASDGGNPVRS 1514



 Score =  353 bits (867), Expect = 5e-95
 Identities = 250/761 (32%), Positives = 379/761 (49%), Gaps = 58/761 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +++ D ND+ PVF   +Y A + E    G ++  ++A+D D G+N++V Y++     +  
Sbjct: 2053 LDISDVNDNPPVFLKSRYIAYLPENNLPGASIYKVQASDLDTGENSKVIYSVFNTNTEAF 2112

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           V   F I+  +G L  + S D E+   + + V+A D   P    L
Sbjct: 2113 P--------------VSSYFSINIETGVLYAQRSFDYEQHKEFAMHVQAKDNGYP---SL 2155

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            SS AT+ + IID NDN P+     Y  + + D  + +    A   A D D+G+NS   Y 
Sbjct: 2156 SSNATLIIRIIDQNDNAPKI---LYPSTENSDSLIFEMVPFAST-AEDPDIGSNSVQTYK 2211

Query: 191  IIGGN----TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            +         +   S  S   ++ L + LD E    + L++ A DGG+P R+ T  + + 
Sbjct: 2212 LSDNQYFTLNEKTSSDGSKFPELVLERPLDRETKNIHELLLTASDGGTPVRTGTALIRVI 2271

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            + D NDN P F   +++ S+SEN PI  +++RV A D DEG NA++TY+ +      +VD
Sbjct: 2272 VTDANDNTPVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSKYFSVD 2331

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
            L    +     +     LDRE +  ++LL+TA+DGG P R+ TA               F
Sbjct: 2332 LE---NGNLYELVLERPLDREIKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVF 2388

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADE--------------DNRLHYEITGGN-TRGR 411
                Y+V ++E+ P  + V+ + A+D DE              +N LH  +   N T G 
Sbjct: 2389 TQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSENSLHASMFSINPTSGE 2448

Query: 412  FS-ITSQNGRGL--ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYA 466
             +  TS +G     + + +PLD + +  + L ++A+D G   R+ TA++++ +TDAN+  
Sbjct: 2449 MNEKTSSDGSKFPELVLERPLDRETKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNT 2508

Query: 467  PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
            PVF    Y  S+ E+ PI +TVL V+A+D D G NAQITYS S    N     H   F I
Sbjct: 2509 PVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVNSL---HASMFSI 2565

Query: 527  NPQTGAITTNKLLDRETMSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585
            NP +G ITTN LL+ E    Y ++V A+D GG  + S    V I + D+NDN P F   L
Sbjct: 2566 NPTSGEITTNNLLNFEAKKDYEISVQAKDGGGFVAHSKVFPVIIEIQDINDNAPKFFPVL 2625

Query: 586  YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR---EEGSFVIDPASGVIRTN 642
            YT +I E+  VG+ V  V ATD D G+N +I Y           +  F I+P +G I+T 
Sbjct: 2626 YTVSISENTAVGSVVLCVNATDKDEGINAQITYSFSKTSESSLNKSMFSINPTTGEIKTE 2685

Query: 643  KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
            K L+ E    ++L   A DGG     S V+  I+I D ND+ P      L+  + E+S  
Sbjct: 2686 KQLNFEGTRNYELSVQAKDGGGFVTHSKVL--IEITDENDNAPEISIASLSTPVPEDSAP 2743

Query: 703  GTTIGEIRAHDPDEGPNAVVHYSIKGGDD-SNSFSLETRQG 742
            G+ I  I  HD D G NA + YSI   +  S  FS+    G
Sbjct: 2744 GSVIALIEVHDQDSGSNAKITYSISETNTMSPYFSINIETG 2784



 Score =  349 bits (858), Expect = 7e-94
 Identities = 239/806 (29%), Positives = 386/806 (47%), Gaps = 62/806 (7%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASS-----GTTVLTLKATDQDIGKNAEVEYTIELV 65
           + V+D ND++P   +      V E A+      G+ + T+ A+D D G+N+ + Y++   
Sbjct: 220 VTVVDVNDNAPEMTVTSLSLPVPEDATHENNPPGSHIYTVSASDSDTGQNSFITYSLRSG 279

Query: 66  TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125
           + +     ++                      +L+ + +LDRE VA Y V + ATD   P
Sbjct: 280 SGNQTYSLNSKFSNYY----------------SLVLKDNLDRESVAEYNVPISATDNGIP 323

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
               LS+TA I+ ++ D NDN P F+E+ Y  S+ E+I      +I ++ A+D D G N+
Sbjct: 324 A---LSTTAYIYFSVDDINDNPPLFTEELYFFSIAENI--LPGSLIFQVSASDKDSGKNA 378

Query: 186 AIRYAII-----GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240
            + YA++     G +     SI+  SG+V  V + DYE++    + +   D G+P  S  
Sbjct: 379 QLLYALLESYVEGMSVSHFISINPDSGNVFSVDSFDYEKIPQKNITVTVTDSGTPPLSTQ 438

Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
             L + + D+NDN P F    +   + EN   G S++ V+A D D   N+ ++Y++    
Sbjct: 439 KTLYVEVSDLNDNPPTFEEKSYSIYIMENNAPGVSLISVKATDLDSNENSFVSYSL---- 494

Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
              +      ++  +G + T+  LDRE  ++Y + + +TD G P  S             
Sbjct: 495 LRASDPKLFQVELHTGEIRTTSFLDRENTSQYNITILSTDRGSPKLSTVKHIRLNISDVN 554

Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRGRFSITSQN 418
                F    Y   L+E+  PG+ +  + A D D  DN ++ Y I G N +  F I   +
Sbjct: 555 DNAPIFKKSTYVAYLSENNLPGSSIYRINAYDPDTGDNAKIIYSIAGTNIKSTFDINPTS 614

Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASV 478
           G+  IT  + LDF+  + Y + + A D GG      V I I D N+ AP    A  +A +
Sbjct: 615 GK--ITTKRDLDFESVQSYEIAIEAMDGGGFVAQTKVLIEIIDENDNAPEISIASLSAPI 672

Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
            ED+  GT + ++   D D G N ++   +      + V+   + +        I T   
Sbjct: 673 PEDSMPGTVIALIKVHDQDTGRNGEVDCQILGAAPFQIVSSSSRYY-------RIITASF 725

Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
           LDRE +  Y +T+ A D G P LS T  +++ + DVNDN PVF +  Y A + E+ L G+
Sbjct: 726 LDREKVPWYNITILATDKGSPELSSTKSIKLDLSDVNDNPPVFSKPTYVAYLPENNLPGS 785

Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
           S+ ++ A D D G N ++ Y +   D    S         +   K LDRE++  H L   
Sbjct: 786 SIYRIQAFDFDSGNNAKVVYSILMSDPSPFSINQYTGEHKVVIMKPLDRENLKIHKLLLT 845

Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
           A DGG P ++ T ++ I I D+ND  P+F  +     ISE+ PI TT+ ++ A D DEG 
Sbjct: 846 AFDGGNPVRTGTALIRIAITDVNDHIPMFTQEVYKVSISESIPINTTVLQVNATDKDEGV 905

Query: 719 NAVVHYSI--KGGDD--SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA----- 769
           NA + YS+    GD   S +FS+    G    E+ T  +L++E  +K YE+ + A     
Sbjct: 906 NAQITYSLIRTSGDSLASATFSINPASG----EIKTKRNLNFE-VQKHYEMSVEAKDGAT 960

Query: 770 --ASPPLWNDVRVEILVTDVNDNAPV 793
              +P       + I+VTD NDN PV
Sbjct: 961 DGGNPKRTGTALLRIIVTDYNDNVPV 986



 Score =  340 bits (835), Expect = 4e-91
 Identities = 255/815 (31%), Positives = 387/815 (47%), Gaps = 68/815 (8%)

Query: 8    HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
            H ++N+ D ND++P+F+   Y A + E    G+++  + A D D G NA++ Y+I     
Sbjct: 545  HIRLNISDVNDNAPIFKKSTYVAYLSENNLPGSSIYRINAYDPDTGDNAKIIYSI----- 599

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
                              ++  F I+  SG + T+  LD E V  Y + ++A D    V+
Sbjct: 600  --------------AGTNIKSTFDINPTSGKITTKRDLDFESVQSYEIAIEAMDGGGFVA 645

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
                    + + IID+NDN P+ S  + +  + ED       VIA IK  D D G N  +
Sbjct: 646  Q-----TKVLIEIIDENDNAPEISIASLSAPIPED--SMPGTVIALIKVHDQDTGRNGEV 698

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
               I+G       S  S    +     LD E+V  Y + I A D GSP  S+T  + +++
Sbjct: 699  DCQILGAAPFQIVSSSSRYYRIITASFLDREKVPWYNITILATDKGSPELSSTKSIKLDL 758

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
             DVNDN P F    +   + EN   G SI R+QA+D D G NA++ Y++   D +     
Sbjct: 759  SDVNDNPPVFSKPTYVAYLPENNLPGSSIYRIQAFDFDSGNNAKVVYSILMSDPS----- 813

Query: 308  PITIDPRSG--WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
            P +I+  +G   V     LDRE    ++LL+TA DGG+P R+ TA               
Sbjct: 814  PFSINQYTGEHKVVIMKPLDRENLKIHKLLLTAFDGGNPVRTGTALIRIAITDVNDHIPM 873

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI--TGGNTRGRFSITSQNGRG 421
            F    Y+V ++E  P  T V+ + ATD DE  + ++ Y +  T G++    + +     G
Sbjct: 874  FTQEVYKVSISESIPINTTVLQVNATDKDEGVNAQITYSLIRTSGDSLASATFSINPASG 933

Query: 422  LITVAQPLDFKQERRYVLTVSATD---SGG---RSDTAMVQINITDANNYAPVFENAPYT 475
             I   + L+F+ ++ Y ++V A D    GG   R+ TA+++I +TD N+  PVF    Y 
Sbjct: 934  EIKTKRNLNFEVQKHYEMSVEAKDGATDGGNPKRTGTALLRIIVTDYNDNVPVFTQQVYK 993

Query: 476  ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
             S+ E API +TV VV+ATD D G N  ITYS S    N   A H Q F INP  G I T
Sbjct: 994  ISISESAPINSTVTVVTATDKDDGTNGHITYSFSRTAEN---AFHTQMFNINPANGEIKT 1050

Query: 536  NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ-------QLYTA 588
             +  D E    + + + A+D G P LS    + I ++D NDN P             +  
Sbjct: 1051 KRSFDYEQHKEFQINIMAKDNGSPPLSSNATLIIHIIDQNDNAPKILYPSTESGGSPFFE 1110

Query: 589  NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE----GSFVIDPASGVIRTNKA 644
             +   ++ G+ ++++ A+D D G N +I Y +   + E+      F I+  +GV+   ++
Sbjct: 1111 MVPFASVQGSLITKIHASDPDAGDNAKIIYSISNINTEDFPVSPYFSINIETGVLYAQRS 1170

Query: 645  LDRESVATHDLKAVAIDGGTPPQSS--TVIVH-IKIEDINDSPPVFESDCLTFYISENSP 701
             D E      +K  A D G+PP SS  T+I+H I+I D ND+ P      L+    E+S 
Sbjct: 1171 FDYEQHKEFQMKISAKDNGSPPLSSNVTLIIHIIEIMDENDNAPEISIRSLSTPFPEDSA 1230

Query: 702  IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761
             GT I  I  HD D G N  V   I G       S  +R      ++V    LD E    
Sbjct: 1231 PGTLIALIEVHDQDSGENGEVECQIIGPSPFQLLSSSSRY----YKIVNTGSLDRELV-P 1285

Query: 762  KYELVIRA---ASPPLWNDVRVEILVTDVNDNAPV 793
             Y + I A    SP L     +++ ++DVNDN P+
Sbjct: 1286 WYNITILATDRGSPQLSTMKFIKLDISDVNDNPPM 1320



 Score =  340 bits (835), Expect = 4e-91
 Identities = 267/905 (29%), Positives = 436/905 (48%), Gaps = 82/905 (9%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++++ D ND++PVF    Y A + E   +G ++  ++A+D D G NA++ Y+I       
Sbjct: 1841 KLDISDVNDNAPVFTKSSYVAYIAENNLAGASIYRIQASDIDAGDNAKIIYSI------- 1893

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLT-RASLDREKVARYTVLVKATDQASPVSD 128
             N E +              F I   +G + + +  LDRE    + +++ A+D   PV  
Sbjct: 1894 YNTEPSP-------------FSISQHTGEIRSSQKPLDRETQKDHELILTASDGGDPVK- 1939

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
              + TA I + + D NDN P F++  Y VS+ E+I +  N  +  + ATD D G N+ I 
Sbjct: 1940 --TGTAIIRIIVTDANDNLPVFTKAVYKVSISENIPI--NSSVLHVNATDRDEGTNAQIT 1995

Query: 189  YAIIGGNTQ----MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
            Y+ I  +        FSI+ ++G++  ++ LD+E  R+Y + ++A DGG     +   +L
Sbjct: 1996 YSFIKTSENDIHSPMFSINQINGEIKTLQKLDFELTRNYEMSVQATDGGGFVAKS---IL 2052

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG- 303
            ++I DVNDN P F  S +   + EN   G SI +VQA D D G N+++ Y++ + +    
Sbjct: 2053 LDISDVNDNPPVFLKSRYIAYLPENNLPGASIYKVQASDLDTGENSKVIYSVFNTNTEAF 2112

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
             V    +I+  +G +Y     D E   ++ + V A D G P  S+ AT            
Sbjct: 2113 PVSSYFSINIETGVLYAQRSFDYEQHKEFAMHVQAKDNGYPSLSSNATLIIRIIDQNDNA 2172

Query: 364  XXFM-PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGR 420
               + P     +    E    P  + TA D D   ++   Y+++          TS +G 
Sbjct: 2173 PKILYPSTENSDSLIFEM--VPFAS-TAEDPDIGSNSVQTYKLSDNQYFTLNEKTSSDGS 2229

Query: 421  GL--ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTA 476
                + + +PLD + +  + L ++A+D G   R+ TA++++ +TDAN+  PVF    Y  
Sbjct: 2230 KFPELVLERPLDRETKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKV 2289

Query: 477  SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
            S+ E+ PI +TVL V+A+D D G NAQITYS S      +V   D +   N     +   
Sbjct: 2290 SISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSKYFSV---DLE---NGNLYELVLE 2343

Query: 537  KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
            + LDRE  + + L +TA DGG P  + T  + + V D NDN PVF Q++Y  +I E+  +
Sbjct: 2344 RPLDREIKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISENTPI 2403

Query: 597  GTSVSQVGATDADVGLNGRIHYELDPKDREE---GSFVIDPASGVIRTN----------- 642
             ++V +V A+D D G N +I Y              F I+P SG +              
Sbjct: 2404 NSTVLRVNASDMDEGTNAQITYSFSRTSENSLHASMFSINPTSGEMNEKTSSDGSKFPEL 2463

Query: 643  ---KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699
               + LDRE+   H+L   A DGGTP ++ T ++ + + D ND+ PVF  +     ISEN
Sbjct: 2464 VLERPLDRETKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISEN 2523

Query: 700  SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759
            +PI +T+  + A D DEG NA + YS      ++  +          E+ T   L++E+ 
Sbjct: 2524 TPINSTVLRVNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEITTNNLLNFEA- 2582

Query: 760  RKKYELVIRAASPPLW----NDVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVGPFG 814
            +K YE+ ++A     +        V I + D+NDNAP  K F +++  +  +   VG   
Sbjct: 2583 KKDYEISVQAKDGGGFVAHSKVFPVIIEIQDINDNAP--KFFPVLYTVSISENTAVGSVV 2640

Query: 815  R-VPAYDAD--VTDKLQYRIL----SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867
              V A D D  +  ++ Y       S  N ++  +N TTG +    QLN    +   + V
Sbjct: 2641 LCVNATDKDEGINAQITYSFSKTSESSLNKSMFSINPTTGEIKTEKQLNFEGTRNYELSV 2700

Query: 868  SVTDG 872
               DG
Sbjct: 2701 QAKDG 2705



 Score =  335 bits (823), Expect = 1e-89
 Identities = 269/902 (29%), Positives = 430/902 (47%), Gaps = 61/902 (6%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + + D ND+ PVF   +Y  SV E    GT      A D DIG N+   Y  EL   D  
Sbjct: 3   VEIEDINDNYPVFPSSRYSISVPESRLPGTRFPLEGAVDADIGTNSITNY--ELSANDYF 60

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             E             + +++I  +S  L+ + SLDREK++ + + + A D   P   +L
Sbjct: 61  TLE-----------LPKFIYQI--KSIQLVLKKSLDREKISVHNLTLMAFDGGKP---KL 104

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY- 189
           S +  + +N+ D NDN P F++  Y  S+ E  +     ++AK+ ATD DVG N    Y 
Sbjct: 105 SGSTQLIINVEDVNDNPPVFNQSVYQCSITE--NAPKGTLVAKLFATDMDVGKNGETSYE 162

Query: 190 --AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
              ++       FS+D  +G+V +   LDYE+  +Y ++I A D G    +   QLL+ +
Sbjct: 163 FSKLVPERMLSLFSLDKYTGEVWVKGELDYEKSNTYEVLIDALDNGEHLLTGHCQLLVTV 222

Query: 248 RDVNDNAPRF-YTSLF----QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
            DVNDNAP    TSL     +++  EN P G  I  V A D+D G N+ +TY++  +  +
Sbjct: 223 VDVNDNAPEMTVTSLSLPVPEDATHENNPPGSHIYTVSASDSDTGQNSFITYSL--RSGS 280

Query: 303 GNVDLPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
           GN    +     + + +     LDRE+ A+Y + ++ATD G P  S TA           
Sbjct: 281 GNQTYSLNSKFSNYYSLVLKDNLDRESVAEYNVPISATDNGIPALSTTAYIYFSVDDIND 340

Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRG---RFSITS 416
               F    Y   +AE+  PG+ +  ++A+D D  ++ +L Y +      G      I+ 
Sbjct: 341 NPPLFTEELYFFSIAENILPGSLIFQVSASDKDSGKNAQLLYALLESYVEGMSVSHFISI 400

Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPY 474
               G +      D+++  +  +TV+ TDSG    S    + + ++D N+  P FE   Y
Sbjct: 401 NPDSGNVFSVDSFDYEKIPQKNITVTVTDSGTPPLSTQKTLYVEVSDLNDNPPTFEEKSY 460

Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
           +  + E+   G +++ V ATD D   N+ ++YSL         A   + F +   TG I 
Sbjct: 461 SIYIMENNAPGVSLISVKATDLDSNENSFVSYSLLR-------ASDPKLFQVELHTGEIR 513

Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
           T   LDRE  S Y +T+ + D G P LS    + +++ DVNDN P+FK+  Y A + E+ 
Sbjct: 514 TTSFLDRENTSQYNITILSTDRGSPKLSTVKHIRLNISDVNDNAPIFKKSTYVAYLSENN 573

Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654
           L G+S+ ++ A D D G N +I Y +      + +F I+P SG I T + LD ESV +++
Sbjct: 574 LPGSSIYRINAYDPDTGDNAKIIYSI-AGTNIKSTFDINPTSGKITTKRDLDFESVQSYE 632

Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
           +   A+DGG     + V+  I+I D ND+ P      L+  I E+S  GT I  I+ HD 
Sbjct: 633 IAIEAMDGGGFVAQTKVL--IEIIDENDNAPEISIASLSAPIPEDSMPGTVIALIKVHDQ 690

Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---AS 771
           D G N  V   I G       S  +R       ++T   LD E     Y + I A    S
Sbjct: 691 DTGRNGEVDCQILGAAPFQIVSSSSRY----YRIITASFLDREKV-PWYNITILATDKGS 745

Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQY 829
           P L +   +++ ++DVNDN PV      +    ++  P     R+ A+D D  +  K+ Y
Sbjct: 746 PELSSTKSIKLDLSDVNDNPPVFSKPTYVAYLPENNLPGSSIYRIQAFDFDSGNNAKVVY 805

Query: 830 RILSGNNANLILLNETTG--SMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887
            IL  ++ +   +N+ TG   + +   L+    K+  + ++  DG N ++    L    I
Sbjct: 806 SILM-SDPSPFSINQYTGEHKVVIMKPLDRENLKIHKLLLTAFDGGNPVRTGTALIRIAI 864

Query: 888 TE 889
           T+
Sbjct: 865 TD 866



 Score =  331 bits (814), Expect = 1e-88
 Identities = 280/899 (31%), Positives = 430/899 (47%), Gaps = 79/899 (8%)

Query: 2    SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
            +V   IH  I ++D ND++P   ++       E ++ GT +  ++  DQD G+N EVE  
Sbjct: 1196 NVTLIIHI-IEIMDENDNAPEISIRSLSTPFPEDSAPGTLIALIEVHDQDSGENGEVECQ 1254

Query: 62   IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121
            I       + P                +     R   ++   SLDRE V  Y + + ATD
Sbjct: 1255 I-------IGPSPF------------QLLSSSSRYYKIVNTGSLDRELVPWYNITILATD 1295

Query: 122  QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181
            + SP   +LS+   I ++I D NDN P F + T+   + E  +      I  I A+D D 
Sbjct: 1296 RGSP---QLSTMKFIKLDISDVNDNPPMFVKSTFVAYLPE--NNLPGASIYSIHASDPDY 1350

Query: 182  GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRS 238
            G N+ I Y+I      + F +DS +G    + T   LD E+   Y + I A D GSP  S
Sbjct: 1351 GNNAKIIYSISNIVGTVPFQLDSSTGRFYRIVTKSALDREKTALYNITIVATDKGSPQLS 1410

Query: 239  NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
            +   + ++I DVNDN P F  S     + EN   G SI R+QA D D G NA++ Y+++ 
Sbjct: 1411 SRKFIRLDISDVNDNPPVFMKSKDVAYLPENNLPGSSIYRIQASDLDTGDNAKVIYSISS 1470

Query: 299  KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358
             D   N D PI+       +     LDRETQ  ++L++TA+DGG+P RS TA        
Sbjct: 1471 MD---NEDFPIS--SYFSKLVLEKPLDRETQTIHELILTASDGGNPVRSGTALIRIAVTD 1525

Query: 359  XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQN 418
                   F    Y+V ++E+ P  + V+T+ ATD DE    + +I        FSI  + 
Sbjct: 1526 SNDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGT--NAQIMYSFRSSFFSINIET 1583

Query: 419  GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAP--VFENAPY 474
              G++   +  D++Q + + + V A D G    S  A + I ITD N+  P  ++ ++  
Sbjct: 1584 --GVLYAQRSFDYEQHKEFQIKVYAKDYGSPSLSCNASLTIRITDQNDNVPKILYPSSES 1641

Query: 475  TASVFEDAPI----GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
              S FE  P+    G  +  V A D+D G NA ++Y +               F I+  T
Sbjct: 1642 VDSSFEMVPVASEQGALITKVVAVDADSGHNAWLSYHV-------VQGSEPSLFSISQNT 1694

Query: 531  GAI-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589
            G I T+ K LDRET + + L +TA DGG P  S T  + I+V D NDN PVF Q++Y  +
Sbjct: 1695 GEIRTSQKPLDRETQTIHELILTASDGGNPVRSGTALIRIAVTDANDNLPVFTQEVYKVS 1754

Query: 590  IM---EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV---IRTNK 643
            I    ED+  GT ++ +   D D G NG    E+D +    G F +  +S     I T  
Sbjct: 1755 ITIIPEDSPSGTLIALIEVHDQDSGENG----EIDCQLLGTGPFQLLLSSTKYYRIITTG 1810

Query: 644  ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703
            +LDRE V  +++   A D G+P  S+  ++ + I D+ND+ PVF       YI+EN+  G
Sbjct: 1811 SLDREKVPWYNITIQATDRGSPHLSNIKLIKLDISDVNDNAPVFTKSSYVAYIAENNLAG 1870

Query: 704  TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY 763
             +I  I+A D D G NA + YSI   + S  FS+    G  ++   +   LD E+ +K +
Sbjct: 1871 ASIYRIQASDIDAGDNAKIIYSIYNTEPS-PFSISQHTGEIRS---SQKPLDRET-QKDH 1925

Query: 764  ELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPAY 819
            EL++ A+    P       + I+VTD NDN PV     +   +  +  P+      V A 
Sbjct: 1926 ELILTASDGGDPVKTGTAIIRIIVTDANDNLPVFTK-AVYKVSISENIPINSSVLHVNAT 1984

Query: 820  DAD--VTDKLQYRIL--SGNNAN--LILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            D D     ++ Y  +  S N+ +  +  +N+  G +    +L+  + +   M V  TDG
Sbjct: 1985 DRDEGTNAQITYSFIKTSENDIHSPMFSINQINGEIKTLQKLDFELTRNYEMSVQATDG 2043



 Score =  330 bits (810), Expect = 4e-88
 Identities = 279/896 (31%), Positives = 423/896 (47%), Gaps = 76/896 (8%)

Query: 20   SPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXX 79
            SP FEM  + ASV+     G+ +  + A+D D G NA++ Y+I       +N ED     
Sbjct: 1106 SPFFEMVPF-ASVQ-----GSLITKIHASDPDAGDNAKIIYSI-----SNINTED----- 1149

Query: 80   XXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTAT--IH 137
                  V   F I+  +G L  + S D E+   + + + A D  SP    LSS  T  IH
Sbjct: 1150 ----FPVSPYFSINIETGVLYAQRSFDYEQHKEFQMKISAKDNGSP---PLSSNVTLIIH 1202

Query: 138  -VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNT 196
             + I+D+NDN P+ S ++ +    ED +     +IA I+  D D G N  +   IIG + 
Sbjct: 1203 IIEIMDENDNAPEISIRSLSTPFPEDSA--PGTLIALIEVHDQDSGENGEVECQIIGPSP 1260

Query: 197  QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256
                S  S    +    +LD E V  Y + I A D GSP  S    + ++I DVNDN P 
Sbjct: 1261 FQLLSSSSRYYKIVNTGSLDRELVPWYNITILATDRGSPQLSTMKFIKLDISDVNDNPPM 1320

Query: 257  FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316
            F  S F   + EN   G SI  + A D D G NA++ Y+++  +  G V  P  +D  +G
Sbjct: 1321 FVKSTFVAYLPENNLPGASIYSIHASDPDYGNNAKIIYSIS--NIVGTV--PFQLDSSTG 1376

Query: 317  WVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373
              Y   T   LDRE  A Y + + ATD G P  S+                 FM  +   
Sbjct: 1377 RFYRIVTKSALDREKTALYNITIVATDKGSPQLSSRKFIRLDISDVNDNPPVFMKSKDVA 1436

Query: 374  ELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431
             L E+  PG+ +  + A+D D  DN ++ Y I+  +    F I+S   +  + + +PLD 
Sbjct: 1437 YLPENNLPGSSIYRIQASDLDTGDNAKVIYSISSMDNED-FPISSYFSK--LVLEKPLDR 1493

Query: 432  KQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
            + +  + L ++A+D G   RS TA+++I +TD+N+  PVF    Y  S+ E+ PI +TVL
Sbjct: 1494 ETQTIHELILTASDGGNPVRSGTALIRIAVTDSNDNLPVFTQEVYKVSISENIPINSTVL 1553

Query: 490  VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
             V+ATD D G NAQI YS  S             F IN +TG +   +  D E    + +
Sbjct: 1554 TVNATDRDEGTNAQIMYSFRSSF-----------FSINIETGVLYAQRSFDYEQHKEFQI 1602

Query: 550  TVTARDGGVPSLSDTTDVEISVVDVNDNEP--VFKQQLYTANIMEDALV----GTSVSQV 603
             V A+D G PSLS    + I + D NDN P  ++       +  E   V    G  +++V
Sbjct: 1603 KVYAKDYGSPSLSCNASLTIRITDQNDNVPKILYPSSESVDSSFEMVPVASEQGALITKV 1662

Query: 604  GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN-KALDRESVATHDLKAVAIDG 662
             A DAD G N  + Y +  +  E   F I   +G IRT+ K LDRE+   H+L   A DG
Sbjct: 1663 VAVDADSGHNAWLSYHV-VQGSEPSLFSISQNTGEIRTSQKPLDRETQTIHELILTASDG 1721

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS---ENSPIGTTIGEIRAHDPDEGPN 719
            G P +S T ++ I + D ND+ PVF  +     I+   E+SP GT I  I  HD D G N
Sbjct: 1722 GNPVRSGTALIRIAVTDANDNLPVFTQEVYKVSITIIPEDSPSGTLIALIEVHDQDSGEN 1781

Query: 720  AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776
              +   + G   +  F L     +    ++T   LD E     Y + I+A    SP L N
Sbjct: 1782 GEIDCQLLG---TGPFQL-LLSSTKYYRIITTGSLDREKV-PWYNITIQATDRGSPHLSN 1836

Query: 777  DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSG 834
               +++ ++DVNDNAPV      +    ++        R+ A D D  D  K+ Y I + 
Sbjct: 1837 IKLIKLDISDVNDNAPVFTKSSYVAYIAENNLAGASIYRIQASDIDAGDNAKIIYSIYN- 1895

Query: 835  NNANLILLNETTGSMTLSPQ-LNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889
               +   +++ TG +  S + L+    K   + ++ +DG + +K    +   ++T+
Sbjct: 1896 TEPSPFSISQHTGEIRSSQKPLDRETQKDHELILTASDGGDPVKTGTAIIRIIVTD 1951



 Score =  329 bits (809), Expect = 6e-88
 Identities = 270/912 (29%), Positives = 426/912 (46%), Gaps = 83/912 (9%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I V D ND+ PVF  + Y+ S+ E     +TVLT+ ATD+D G NA++ Y+        
Sbjct: 1520 RIAVTDSNDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQIMYSFR------ 1573

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                                F I+  +G L  + S D E+   + + V A D  SP    
Sbjct: 1574 -----------------SSFFSINIETGVLYAQRSFDYEQHKEFQIKVYAKDYGSP---S 1613

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVT-----DNPVIAKIKATDADVGAN 184
            LS  A++ + I D NDN P+    + + SVD    +         +I K+ A DAD G N
Sbjct: 1614 LSCNASLTIRITDQNDNVPKILYPS-SESVDSSFEMVPVASEQGALITKVVAVDADSGHN 1672

Query: 185  SAIRYAIIGGNTQMQFSIDSLSGDV-SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
            + + Y ++ G+    FSI   +G++ +  K LD E    + L++ A DGG+P RS T  +
Sbjct: 1673 AWLSYHVVQGSEPSLFSISQNTGEIRTSQKPLDRETQTIHELILTASDGGNPVRSGTALI 1732

Query: 244  LINIRDVNDNAPRFYTSLFQESVS---ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
             I + D NDN P F   +++ S++   E+ P G  I  ++ +D D G N E+   +    
Sbjct: 1733 RIAVTDANDNLPVFTQEVYKVSITIIPEDSPSGTLIALIEVHDQDSGENGEIDCQLLG-- 1790

Query: 301  YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
             TG   L ++   +   + T+G LDRE    Y + + ATD G P  S             
Sbjct: 1791 -TGPFQLLLS-STKYYRIITTGSLDREKVPWYNITIQATDRGSPHLSNIKLIKLDISDVN 1848

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTR-GRFSITSQNG 419
                 F    Y   +AE+   G  +  + A+D D  +      +  NT    FSI+   G
Sbjct: 1849 DNAPVFTKSSYVAYIAENNLAGASIYRIQASDIDAGDNAKIIYSIYNTEPSPFSISQHTG 1908

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTAS 477
              + +  +PLD + ++ + L ++A+D G   ++ TA+++I +TDAN+  PVF  A Y  S
Sbjct: 1909 E-IRSSQKPLDRETQKDHELILTASDGGDPVKTGTAIIRIIVTDANDNLPVFTKAVYKVS 1967

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            + E+ PI ++VL V+ATD D G NAQITYS      N+    H   F IN   G I T +
Sbjct: 1968 ISENIPINSSVLHVNATDRDEGTNAQITYSFIKTSENDI---HSPMFSINQINGEIKTLQ 2024

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
             LD E    Y ++V A DGG   ++ +  ++IS  DVNDN PVF +  Y A + E+ L G
Sbjct: 2025 KLDFELTRNYEMSVQATDGG-GFVAKSILLDIS--DVNDNPPVFLKSRYIAYLPENNLPG 2081

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDRE----EGSFVIDPASGVIRTNKALDRESVATH 653
             S+ +V A+D D G N ++ Y +   + E       F I+  +GV+   ++ D E     
Sbjct: 2082 ASIYKVQASDLDTGENSKVIYSVFNTNTEAFPVSSYFSINIETGVLYAQRSFDYEQHKEF 2141

Query: 654  DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF------ESDCLTFYISENSPIGTTIG 707
             +   A D G P  SS   + I+I D ND+ P         SD L F   E  P  +T  
Sbjct: 2142 AMHVQAKDNGYPSLSSNATLIIRIIDQNDNAPKILYPSTENSDSLIF---EMVPFAST-- 2196

Query: 708  EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA---ELVTMVDLDYESPRKKYE 764
               A DPD G N+V  Y +    D+  F+L  +  SD +   ELV    LD E+ +  +E
Sbjct: 2197 ---AEDPDIGSNSVQTYKL---SDNQYFTLNEKTSSDGSKFPELVLERPLDRET-KNIHE 2249

Query: 765  LVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPAYD 820
            L++ A+   +P       + ++VTD NDN PV    ++   +  +  P+     RV A D
Sbjct: 2250 LLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQ-EVYKVSISENTPINSTVLRVNASD 2308

Query: 821  ADVTDKLQYRILSGNNANLILLNETTGS---MTLSPQLNTNVPKLATMEVSVTDGVNEIK 877
             D     Q        +    ++   G+   + L   L+  +  +  + ++ +DG   ++
Sbjct: 2309 MDEGTNAQITYSFSRTSKYFSVDLENGNLYELVLERPLDREIKNIHELLLTASDGGTPVR 2368

Query: 878  AMMQLSVRLITE 889
                L   ++T+
Sbjct: 2369 TGTALIRVIVTD 2380



 Score =  329 bits (809), Expect = 6e-88
 Identities = 253/787 (32%), Positives = 393/787 (49%), Gaps = 50/787 (6%)

Query: 89   VFRIDGRSGALLT-RASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
            +F I   +G + T +  LDRE    + +++ A+D  +PV    S TA I + + D NDN 
Sbjct: 1687 LFSISQNTGEIRTSQKPLDRETQTIHELILTASDGGNPVR---SGTALIRIAVTDANDNL 1743

Query: 148  PQFSEKTYTVSVDEDISVTDNP---VIAKIKATDADVGANSAIRYAIIG-GNTQMQFSID 203
            P F+++ Y VS+   I   D+P   +IA I+  D D G N  I   ++G G  Q+  S  
Sbjct: 1744 PVFTQEVYKVSIT--IIPEDSPSGTLIALIEVHDQDSGENGEIDCQLLGTGPFQLLLSST 1801

Query: 204  SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263
                 ++   +LD E+V  Y + I+A D GSP  SN   + ++I DVNDNAP F  S + 
Sbjct: 1802 KYYRIIT-TGSLDREKVPWYNITIQATDRGSPHLSNIKLIKLDISDVNDNAPVFTKSSYV 1860

Query: 264  ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323
              ++EN   G SI R+QA D D G NA++ Y++ + + +     P +I   +G + +S +
Sbjct: 1861 AYIAENNLAGASIYRIQASDIDAGDNAKIIYSIYNTEPS-----PFSISQHTGEIRSSQK 1915

Query: 324  -LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382
             LDRETQ  ++L++TA+DGGDP ++ TA               F    Y+V ++E+ P  
Sbjct: 1916 PLDRETQKDHELILTASDGGDPVKTGTAIIRIIVTDANDNLPVFTKAVYKVSISENIPIN 1975

Query: 383  TPVVTLTATDADEDN--RLHYEI--TGGNT--RGRFSITSQNGRGLITVAQPLDFKQERR 436
            + V+ + ATD DE    ++ Y    T  N      FSI   NG   I   Q LDF+  R 
Sbjct: 1976 SSVLHVNATDRDEGTNAQITYSFIKTSENDIHSPMFSINQINGE--IKTLQKLDFELTRN 2033

Query: 437  YVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496
            Y ++V ATD GG    +++ ++I+D N+  PVF  + Y A + E+   G ++  V A+D 
Sbjct: 2034 YEMSVQATDGGGFVAKSIL-LDISDVNDNPPVFLKSRYIAYLPENNLPGASIYKVQASDL 2092

Query: 497  DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556
            D G N+++ YS+ +  +N         F IN +TG +   +  D E    + + V A+D 
Sbjct: 2093 DTGENSKVIYSVFN--TNTEAFPVSSYFSINIETGVLYAQRSFDYEQHKEFAMHVQAKDN 2150

Query: 557  GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG-ATDADVGLNGR 615
            G PSLS    + I ++D NDN P     LY +    D+L+   V     A D D+G N  
Sbjct: 2151 GYPSLSSNATLIIRIIDQNDNAPKI---LYPSTENSDSLIFEMVPFASTAEDPDIGSNSV 2207

Query: 616  IHYELDPKDR---EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672
              Y+L         E +         +   + LDRE+   H+L   A DGGTP ++ T +
Sbjct: 2208 QTYKLSDNQYFTLNEKTSSDGSKFPELVLERPLDRETKNIHELLLTASDGGTPVRTGTAL 2267

Query: 673  VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732
            + + + D ND+ PVF  +     ISEN+PI +T+  + A D DEG NA + YS      S
Sbjct: 2268 IRVIVTDANDNTPVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSR--TS 2325

Query: 733  NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVND 789
              FS++   G+   ELV    LD E  +  +EL++ A+   +P       + ++VTD ND
Sbjct: 2326 KYFSVDLENGN-LYELVLERPLDREI-KNIHELLLTASDGGTPVRTGTALIRVIVTDAND 2383

Query: 790  NAPVMKDFQIIFNNYKDCFPV-GPFGRVPAYDADVTDKLQ----YRILSGN--NANLILL 842
            N PV    ++   +  +  P+     RV A D D     Q    +   S N  +A++  +
Sbjct: 2384 NTPVFTQ-EVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSENSLHASMFSI 2442

Query: 843  NETTGSM 849
            N T+G M
Sbjct: 2443 NPTSGEM 2449



 Score =  328 bits (807), Expect = 1e-87
 Identities = 218/704 (30%), Positives = 352/704 (50%), Gaps = 30/704 (4%)

Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDED-ISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194
           + V I D NDNYP F    Y++SV E  +  T  P+     A DAD+G NS   Y +   
Sbjct: 1   VDVEIEDINDNYPVFPSSRYSISVPESRLPGTRFPLEG---AVDADIGTNSITNYELSAN 57

Query: 195 N----TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
           +       +F     S  + L K+LD E++  + L + A DGG P  S +TQL+IN+ DV
Sbjct: 58  DYFTLELPKFIYQIKSIQLVLKKSLDREKISVHNLTLMAFDGGKPKLSGSTQLIINVEDV 117

Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
           NDN P F  S++Q S++EN P G  + ++ A D D G N E +Y  +       + L  +
Sbjct: 118 NDNPPVFNQSVYQCSITENAPKGTLVAKLFATDMDVGKNGETSYEFSKLVPERMLSL-FS 176

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
           +D  +G V+  G+LD E    Y++L+ A D G+   +                       
Sbjct: 177 LDKYTGEVWVKGELDYEKSNTYEVLIDALDNGEHLLTGHCQLLVTVVDVNDNAPEMTVTS 236

Query: 371 YEVELAED-----EPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQ-NGRGL 422
             + + ED      PPG+ + T++A+D+D  +++ + Y +  G+    +S+ S+ +    
Sbjct: 237 LSLPVPEDATHENNPPGSHIYTVSASDSDTGQNSFITYSLRSGSGNQTYSLNSKFSNYYS 296

Query: 423 ITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
           + +   LD +    Y + +SATD+G    S TA +  ++ D N+  P+F    Y  S+ E
Sbjct: 297 LVLKDNLDRESVAEYNVPISATDNGIPALSTTAYIYFSVDDINDNPPLFTEELYFFSIAE 356

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYS-LSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           +   G+ +  VSA+D D G NAQ+ Y+ L S +   +V+H      INP +G + +    
Sbjct: 357 NILPGSLIFQVSASDKDSGKNAQLLYALLESYVEGMSVSHF---ISINPDSGNVFSVDSF 413

Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
           D E +    +TVT  D G P LS    + + V D+NDN P F+++ Y+  IME+   G S
Sbjct: 414 DYEKIPQKNITVTVTDSGTPPLSTQKTLYVEVSDLNDNPPTFEEKSYSIYIMENNAPGVS 473

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
           +  V ATD D   N  + Y L  +  +   F ++  +G IRT   LDRE+ + +++  ++
Sbjct: 474 LISVKATDLDSNENSFVSYSL-LRASDPKLFQVELHTGEIRTTSFLDRENTSQYNITILS 532

Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
            D G+P  S+   + + I D+ND+ P+F+      Y+SEN+  G++I  I A+DPD G N
Sbjct: 533 TDRGSPKLSTVKHIRLNISDVNDNAPIFKKSTYVAYLSENNLPGSSIYRINAYDPDTGDN 592

Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDV 778
           A + YSI G +  ++F +    G    ++ T  DLD+ES  + YE+ I A          
Sbjct: 593 AKIIYSIAGTNIKSTFDINPTSG----KITTKRDLDFESV-QSYEIAIEAMDGGGFVAQT 647

Query: 779 RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD 822
           +V I + D NDNAP +    +     +D  P      +  +D D
Sbjct: 648 KVLIEIIDENDNAPEISIASLSAPIPEDSMPGTVIALIKVHDQD 691



 Score =  278 bits (681), Expect = 2e-72
 Identities = 188/567 (33%), Positives = 283/567 (49%), Gaps = 40/567 (7%)

Query: 99   LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158
            L+    LDRE    + +L+ A+D  +PV    + TA I V + D NDN P F+++ Y VS
Sbjct: 2234 LVLERPLDRETKNIHELLLTASDGGTPVR---TGTALIRVIVTDANDNTPVFTQEVYKVS 2290

Query: 159  VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG---DVSLVKTL 215
            + E+  +  N  + ++ A+D D G N+ I Y+     T   FS+D  +G   ++ L + L
Sbjct: 2291 ISENTPI--NSTVLRVNASDMDEGTNAQITYSF--SRTSKYFSVDLENGNLYELVLERPL 2346

Query: 216  DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275
            D E    + L++ A DGG+P R+ T  + + + D NDN P F   +++ S+SEN PI  +
Sbjct: 2347 DREIKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISENTPINST 2406

Query: 276  IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY--TSGQ---------- 323
            ++RV A D DEG NA++TY+ +            +I+P SG +   TS            
Sbjct: 2407 VLRVNASDMDEGTNAQITYSFSRTSENSLHASMFSINPTSGEMNEKTSSDGSKFPELVLE 2466

Query: 324  --LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381
              LDRET+  ++LL+TA+DGG P R+ TA               F    Y+V ++E+ P 
Sbjct: 2467 RPLDRETKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISENTPI 2526

Query: 382  GTPVVTLTATDADEDNRLHYEITGGNTR------GRFSITSQNGRGLITVAQPLDFKQER 435
             + V+ + A+D DE        +   T         FSI   +G   IT    L+F+ ++
Sbjct: 2527 NSTVLRVNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGE--ITTNNLLNFEAKK 2584

Query: 436  RYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492
             Y ++V A D GG    S    V I I D N+ AP F    YT S+ E+  +G+ VL V+
Sbjct: 2585 DYEISVQAKDGGGFVAHSKVFPVIIEIQDINDNAPKFFPVLYTVSISENTAVGSVVLCVN 2644

Query: 493  ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552
            ATD D GINAQITYS S    +     +   F INP TG I T K L+ E    Y L+V 
Sbjct: 2645 ATDKDEGINAQITYSFSKTSESSL---NKSMFSINPTTGEIKTEKQLNFEGTRNYELSVQ 2701

Query: 553  ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612
            A+DGG       + V I + D NDN P       +  + ED+  G+ ++ +   D D G 
Sbjct: 2702 AKDGG--GFVTHSKVLIEITDENDNAPEISIASLSTPVPEDSAPGSVIALIEVHDQDSGS 2759

Query: 613  NGRIHYELDPKDREEGSFVIDPASGVI 639
            N +I Y +   +     F I+  +GV+
Sbjct: 2760 NAKITYSISETNTMSPYFSINIETGVL 2786



 Score =  193 bits (471), Expect = 5e-47
 Identities = 121/419 (28%), Positives = 208/419 (49%), Gaps = 18/419 (4%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ V D ND++PVF  + Y+ S+ E     +TVL + A+D D G NA++ Y+    + ++
Sbjct: 2375 RVIVTDANDNTPVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSENS 2434

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
            L+   +          + +    DG +   L+    LDRE    + +L+ A+D  +PV  
Sbjct: 2435 LHA--SMFSINPTSGEMNEKTSSDGSKFPELVLERPLDRETKNIHELLLTASDGGTPVR- 2491

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
              + TA I V + D NDN P F+++ Y VS+ E+  +  N  + ++ A+D D G N+ I 
Sbjct: 2492 --TGTALIRVIVTDANDNTPVFTQEVYKVSISENTPI--NSTVLRVNASDMDEGTNAQIT 2547

Query: 189  YAI----IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS-PSRSNTTQL 243
            Y+     +       FSI+  SG+++    L++E  + Y + ++A+DGG   + S    +
Sbjct: 2548 YSFSRTSVNSLHASMFSINPTSGEITTNNLLNFEAKKDYEISVQAKDGGGFVAHSKVFPV 2607

Query: 244  LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
            +I I+D+NDNAP+F+  L+  S+SEN  +G  ++ V A D DEG+NA++TY+ +    + 
Sbjct: 2608 IIEIQDINDNAPKFFPVLYTVSISENTAVGSVVLCVNATDKDEGINAQITYSFSKTSESS 2667

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
                  +I+P +G + T  QL+ E    Y+L V A DGG     +               
Sbjct: 2668 LNKSMFSINPTTGEIKTEKQLNFEGTRNYELSVQAKDGGGFVTHSKVLIEITDENDNAPE 2727

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRG-RFSITSQNG 419
                       + ED  PG+ +  +   D D  +  ++ Y I+  NT    FSI  + G
Sbjct: 2728 ISI--ASLSTPVPEDSAPGSVIALIEVHDQDSGSNAKITYSISETNTMSPYFSINIETG 2784



 Score =  178 bits (433), Expect = 2e-42
 Identities = 132/416 (31%), Positives = 205/416 (49%), Gaps = 27/416 (6%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           V + I D N+  PVF ++ Y+ SV E    GT   +  A D+D+G N+   Y LS+   N
Sbjct: 1   VDVEIEDINDNYPVFPSSRYSISVPESRLPGTRFPLEGAVDADIGTNSITNYELSA---N 57

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
           +       +F+   ++  +   K LDRE +S + LT+ A DGG P LS +T + I+V DV
Sbjct: 58  DYFTLELPKFIYQIKSIQLVLKKSLDREKISVHNLTLMAFDGGKPKLSGSTQLIINVEDV 117

Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP--KDREEGSFVI 632
           NDN PVF Q +Y  +I E+A  GT V+++ ATD DVG NG   YE      +R    F +
Sbjct: 118 NDNPPVFNQSVYQCSITENAPKGTLVAKLFATDMDVGKNGETSYEFSKLVPERMLSLFSL 177

Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692
           D  +G +     LD E   T+++   A+D G    +    + + + D+ND+ P      L
Sbjct: 178 DKYTGEVWVKGELDYEKSNTYEVLIDALDNGEHLLTGHCQLLVTVVDVNDNAPEMTVTSL 237

Query: 693 TFYI-----SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747
           +  +      EN+P G+ I  + A D D G N+ + YS++ G  + ++SL ++  S+   
Sbjct: 238 SLPVPEDATHENNPPGSHIYTVSASDSDTGQNSFITYSLRSGSGNQTYSLNSK-FSNYYS 296

Query: 748 LVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY 804
           LV   +LD ES   +Y + I A     P L     +   V D+NDN P+  +    F+  
Sbjct: 297 LVLKDNLDRESV-AEYNVPISATDNGIPALSTTAYIYFSVDDINDNPPLFTEELYFFSIA 355

Query: 805 KDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLI--LLNETTGSMTLSPQLNTN 858
           ++  P     +V A D D          SG NA L+  LL      M++S  ++ N
Sbjct: 356 ENILPGSLIFQVSASDKD----------SGKNAQLLYALLESYVEGMSVSHFISIN 401


>UniRef50_Q17NI8 Cluster: Cadherin; n=3; cellular organisms|Rep:
            Cadherin - Aedes aegypti (Yellowfever mosquito)
          Length = 3131

 Score =  372 bits (914), Expect = e-100
 Identities = 285/891 (31%), Positives = 417/891 (46%), Gaps = 81/891 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I+V+D     P+F+  +Y   V+E     T V T+ AT  + G    + Y I     D  
Sbjct: 442  ISVIDATQRPPIFDKPRYTYYVKEDVKKNTVVGTVSATSSNSGSRGSIRYFIYSGDPD-- 499

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F ID  SG +   ++LD E   +  + ++AT    P     
Sbjct: 500  -----------------GYFAIDPVSGNIRVASTLDHETKPQVLLNIQATSGDPPAYGHT 542

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
                 ++++I D NDN P+F   T  +SV E++ +  +P+ A   A D D G +  I Y 
Sbjct: 543  Q----VNIDIEDVNDNPPEFESSTVRISVPENVEI-GSPLYAA-NAHDKDSGMSGVITYR 596

Query: 191  II--GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            +   G  T   FSIDS SG +SL + LDYE V+ + L++ A D G PS S    +L+ ++
Sbjct: 597  LSNNGPATGNLFSIDSRSGHLSLARPLDYETVQRHTLIVTASDSGIPSLSTNLTILVEVQ 656

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY---TG-- 303
            DVNDNAP F  S +   VSE+ P    I++V A DAD G NA LTY +   D    TG  
Sbjct: 657  DVNDNAPVFERSEYAIKVSESTPSNSQIMQVTAVDADTGNNARLTYRILGDDQRTRTGKS 716

Query: 304  -------NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
                   N      I P SGW+Y   +LDRE Q +Y + V  +D G P  +AT       
Sbjct: 717  SSKASEANTPEIFGIFPNSGWIYLRTKLDREDQERYNITVIVSDNGVPTLTATTHVIVSV 776

Query: 357  XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSI 414
                     F    YE ++ E+   G+ +  +TATDAD   +  + Y +   NT   F I
Sbjct: 777  LDANDNNPIFAKQLYEFQIEENMRRGSVIGLITATDADAGINAVVRYSLIPSNT--SFQI 834

Query: 415  TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAP-VFEN 471
               +G   IT    LD + +  Y L V A D G   RS    ++I I D N+ +P + + 
Sbjct: 835  NPISGE--ITTRDRLDRETKSIYDLVVEARDQGTPYRSSRVSIKIKILDVNDNSPEIVDP 892

Query: 472  APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
                 SV E+ PIGT V+ V A D D G+NA ITYS+      ++  H    F I+P TG
Sbjct: 893  QEDVVSVREEQPIGTEVVRVRAIDRDYGVNASITYSILK--GRDSDGH--GMFTIDPITG 948

Query: 532  AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
             I T   LD E  + Y L V A D G P       + I V+D+NDN P F        + 
Sbjct: 949  LIRTKASLDHEEKTIYRLAVAATDNGKPPRQTVRLLRIEVLDLNDNRPTFTSSSLVFRLR 1008

Query: 592  EDALVGTSVSQVGATDAD-----VGLNGRIH--YELDP--KDREEGSFVIDPASGVIRTN 642
            ED  VG  +  +   +       +  +  +H  Y L P   D  EG+F ID  SG +   
Sbjct: 1009 EDVGVGHVIGSISGNEQSDLENLITSSNDLHITYTLTPLTNDIAEGAFDIDRNSGKLVVA 1068

Query: 643  KALDRESVATHDLKAVAID--GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700
            ++LDRE  + + ++  A+D      PQSS V V I+I D+ND+PP + SD +  YISE++
Sbjct: 1069 RSLDREQQSEYRMEIRALDTSASNNPQSSAVTVKIEIADVNDNPPKWPSDPMNVYISEDA 1128

Query: 701  PIGTTIGEIRAHDPDEGPNAVVHYSIK--GGDDSNSFSLETRQGSDKAELVTMVDLDYES 758
             +G+ +    A D D G NA + Y+I          FS+++  GS    L  +  LDYE 
Sbjct: 1129 AVGSVVFNFTATDNDSGTNAEIKYNISKPATAQKEFFSIDSLTGS----LTLLAPLDYEE 1184

Query: 759  PRKKYELVIRA------ASPPLWNDVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFPV 810
              K++ L+++A       +  +       I+VTDVNDN+P  V+   Q       D   V
Sbjct: 1185 -TKEFLLIVQATDQSSNVTERMTTSATARIMVTDVNDNSPKFVVPQAQDTTVYVSDSMEV 1243

Query: 811  GPF-GRVPAYDADVTD--KLQYRILSGNNANLILLNETTGSMTLSPQLNTN 858
                  V A D D  +  ++ Y+I+SGN      ++  TG + L+   ++N
Sbjct: 1244 NHIVSHVVAIDRDSGENGRVVYKIVSGNEDERFAIDPDTGFVKLAKPFSSN 1294



 Score =  357 bits (878), Expect = 2e-96
 Identities = 282/919 (30%), Positives = 439/919 (47%), Gaps = 85/919 (9%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSG----TTVLTLKATDQDIGKNAEVEYTIELV 65
            +I + D ND+ P F  ++Y  S+RE   +     T V+ + ATD D G    + Y I  V
Sbjct: 330  KIQLTDVNDNRPTFYPREYNVSLRESMPTNSLLSTPVVVIVATDSDSGSFGTISYRI--V 387

Query: 66   TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVL-VKATDQA 123
              +                    +FR+D  +G + + R ++   +   Y  L + A+D  
Sbjct: 388  AGNEAG-----------------IFRMDRLTGEIFVARPNMLSSRSQPYHRLNISASDGG 430

Query: 124  SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183
                 R +  A + +++ID     P F +  YT  V ED+    N V+  + AT ++ G+
Sbjct: 431  GL---RSTHDAEVFISVIDATQRPPIFDKPRYTYYVKEDVK--KNTVVGTVSATSSNSGS 485

Query: 184  NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
              +IRY I  G+    F+ID +SG++ +  TLD+E      L I+A  G  P+  +T Q+
Sbjct: 486  RGSIRYFIYSGDPDGYFAIDPVSGNIRVASTLDHETKPQVLLNIQATSGDPPAYGHT-QV 544

Query: 244  LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD-YT 302
             I+I DVNDN P F +S  + SV ENV IG  +    A+D D G++  +TY +++    T
Sbjct: 545  NIDIEDVNDNPPEFESSTVRISVPENVEIGSPLYAANAHDKDSGMSGVITYRLSNNGPAT 604

Query: 303  GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
            GN+    +ID RSG +  +  LD ET  ++ L+VTA+D G P  S   T           
Sbjct: 605  GNL---FSIDSRSGHLSLARPLDYETVQRHTLIVTASDSGIPSLSTNLTILVEVQDVNDN 661

Query: 363  XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGR 420
               F   +Y ++++E  P  + ++ +TA DAD  N  RL Y I G + R R   +S    
Sbjct: 662  APVFERSEYAIKVSESTPSNSQIMQVTAVDADTGNNARLTYRILGDDQRTRTGKSSSKAS 721

Query: 421  --------------GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANN 464
                          G I +   LD + + RY +TV  +D+G  + TA   V +++ DAN+
Sbjct: 722  EANTPEIFGIFPNSGWIYLRTKLDREDQERYNITVIVSDNGVPTLTATTHVIVSVLDAND 781

Query: 465  YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524
              P+F    Y   + E+   G+ + +++ATD+D GINA + YSL    SN +       F
Sbjct: 782  NNPIFAKQLYEFQIEENMRRGSVIGLITATDADAGINAVVRYSLIP--SNTS-------F 832

Query: 525  VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP-VFKQ 583
             INP +G ITT   LDRET S Y L V ARD G P  S    ++I ++DVNDN P +   
Sbjct: 833  QINPISGEITTRDRLDRETKSIYDLVVEARDQGTPYRSSRVSIKIKILDVNDNSPEIVDP 892

Query: 584  QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE-LDPKDRE-EGSFVIDPASGVIRT 641
            Q    ++ E+  +GT V +V A D D G+N  I Y  L  +D +  G F IDP +G+IRT
Sbjct: 893  QEDVVSVREEQPIGTEVVRVRAIDRDYGVNASITYSILKGRDSDGHGMFTIDPITGLIRT 952

Query: 642  NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701
              +LD E    + L   A D G PP+ +  ++ I++ D+ND+ P F S  L F + E+  
Sbjct: 953  KASLDHEEKTIYRLAVAATDNGKPPRQTVRLLRIEVLDLNDNRPTFTSSSLVFRLREDVG 1012

Query: 702  IGTTIGEIRAHDPDEGPNAV-------VHYSIKG-GDDSNSFSLETRQGSDKAELVTMVD 753
            +G  IG I  ++  +  N +       + Y++    +D    + +  + S K  LV    
Sbjct: 1013 VGHVIGSISGNEQSDLENLITSSNDLHITYTLTPLTNDIAEGAFDIDRNSGK--LVVARS 1070

Query: 754  LDYESPRKKYELVIRA-----ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCF 808
            LD E  + +Y + IRA     ++ P  + V V+I + DVNDN P      +     +D  
Sbjct: 1071 LDREQ-QSEYRMEIRALDTSASNNPQSSAVTVKIEIADVNDNPPKWPSDPMNVYISEDAA 1129

Query: 809  PVGPFGRVPAYDAD--VTDKLQYRILSGNNAN--LILLNETTGSMTLSPQLNTNVPKLAT 864
                     A D D     +++Y I     A      ++  TGS+TL   L+    K   
Sbjct: 1130 VGSVVFNFTATDNDSGTNAEIKYNISKPATAQKEFFSIDSLTGSLTLLAPLDYEETKEFL 1189

Query: 865  MEVSVTDGVNEIKAMMQLS 883
            + V  TD  + +   M  S
Sbjct: 1190 LIVQATDQSSNVTERMTTS 1208



 Score =  353 bits (867), Expect = 5e-95
 Identities = 269/906 (29%), Positives = 420/906 (46%), Gaps = 66/906 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V D ND++PVFE  +Y   V E   S + ++ + A D D G NA + Y I     D  
Sbjct: 653  VEVQDVNDNAPVFERSEYAIKVSESTPSNSQIMQVTAVDADTGNNARLTYRI---LGDDQ 709

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                             ++F I   SG +  R  LDRE   RY + V  +D   P    L
Sbjct: 710  RTRTGKSSSKASEANTPEIFGIFPNSGWIYLRTKLDREDQERYNITVIVSDNGVPT---L 766

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            ++T  + V+++D NDN P F+++ Y   ++E  ++    VI  I ATDAD G N+ +RY+
Sbjct: 767  TATTHVIVSVLDANDNNPIFAKQLYEFQIEE--NMRRGSVIGLITATDADAGINAVVRYS 824

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            +I  NT   F I+ +SG+++    LD E    Y LV+ A+D G+P RS+   + I I DV
Sbjct: 825  LIPSNT--SFQINPISGEITTRDRLDRETKSIYDLVVEARDQGTPYRSSRVSIKIKILDV 882

Query: 251  NDNAPRFYTSLFQ-ESVSENVPIGYSIVRVQAYDADEGVNAELTYT-MTDKDYTGNVDLP 308
            NDN+P          SV E  PIG  +VRV+A D D GVNA +TY+ +  +D  G+    
Sbjct: 883  NDNSPEIVDPQEDVVSVREEQPIGTEVVRVRAIDRDYGVNASITYSILKGRDSDGHG--M 940

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
             TIDP +G + T   LD E +  Y+L V ATD G PPR                   F  
Sbjct: 941  FTIDPITGLIRTKASLDHEEKTIYRLAVAATDNGKPPRQTVRLLRIEVLDLNDNRPTFTS 1000

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADE-------DNRLHY-----EITGGNTRGRFSITS 416
                  L ED   G  + +++  +  +        N LH       +T     G F I  
Sbjct: 1001 SSLVFRLREDVGVGHVIGSISGNEQSDLENLITSSNDLHITYTLTPLTNDIAEGAFDIDR 1060

Query: 417  QNGRGLITVAQPLDFKQERRYVLTVSATDSGG----RSDTAMVQINITDANNYAPVFENA 472
             +G+  + VA+ LD +Q+  Y + + A D+      +S    V+I I D N+  P + + 
Sbjct: 1061 NSGK--LVVARSLDREQQSEYRMEIRALDTSASNNPQSSAVTVKIEIADVNDNPPKWPSD 1118

Query: 473  PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
            P    + EDA +G+ V   +ATD+D G NA+I Y+    IS  A A   + F I+  TG+
Sbjct: 1119 PMNVYISEDAAVGSVVFNFTATDNDSGTNAEIKYN----ISKPATA-QKEFFSIDSLTGS 1173

Query: 533  ITTNKLLDRETMSGYLLTVTARDGG---VPSLSDTTDVEISVVDVNDNEPVF---KQQLY 586
            +T    LD E    +LL V A D        ++ +    I V DVNDN P F   + Q  
Sbjct: 1174 LTLLAPLDYEETKEFLLIVQATDQSSNVTERMTTSATARIMVTDVNDNSPKFVVPQAQDT 1233

Query: 587  TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646
            T  + +   V   VS V A D D G NGR+ Y++     E+  F IDP +G ++  K   
Sbjct: 1234 TVYVSDSMEVNHIVSHVVAIDRDSGENGRVVYKI-VSGNEDERFAIDPDTGFVKLAKPFS 1292

Query: 647  RESVA---------THDLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696
               +A          ++L   A D GTP  + + + + + I++ +++PP F        I
Sbjct: 1293 SNFIADNSKNSITGRYNLVITATDQGTPRSKEAKITIQVVIQNTSNNPPRFLESVYHINI 1352

Query: 697  SENSPIGTTIGEIRAHDPDEGPNAVVHYSI-KG-GDD----SNSFSLETRQGSDKAELVT 750
            +EN P G+ +  + A   ++  NA + Y I KG GDD     +   + T +G+   E   
Sbjct: 1353 TENVPTGSFVVRVSAKSYNDNGNANLTYEIPKGVGDDHFVVDSVRGIVTTRGTFDRESKD 1412

Query: 751  MVDLD-YESPRKKYELVIRAASPPL--WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC 807
            M  +  Y + + +++      S  +  ++   + + +TDVND+AP             + 
Sbjct: 1413 MYTVPIYVTEQNRFKSAASGTSKDMSQFDVATLVVRITDVNDHAPEFLPGSCYPLAVPEN 1472

Query: 808  FPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATM 865
              +     V A DAD  +  ++ Y I  GN  N   ++  TG++T  P L+  +     +
Sbjct: 1473 SELSVIHTVVASDADEGLNGEITYSISGGNIGNKFSIDMNTGALTARP-LDREIHARYVL 1531

Query: 866  EVSVTD 871
            +++  D
Sbjct: 1532 QITAQD 1537



 Score =  343 bits (842), Expect = 6e-92
 Identities = 250/778 (32%), Positives = 375/778 (48%), Gaps = 53/778 (6%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            F I   +G +   A LD E    Y   + ATD+       LS+TA + + + D NDN P 
Sbjct: 288  FEIRSSTGEVCIAAELDYETRNSYEFPIIATDRGG-----LSTTAMVKIQLTDVNDNRPT 342

Query: 150  FSEKTYTVSVDEDI---SVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206
            F  + Y VS+ E +   S+   PV+  I ATD+D G+   I Y I+ GN    F +D L+
Sbjct: 343  FYPREYNVSLRESMPTNSLLSTPVVV-IVATDSDSGSFGTISYRIVAGNEAGIFRMDRLT 401

Query: 207  GDVSLVK--TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF----YTS 260
            G++ + +   L       +RL I A DGG    ++  ++ I++ D     P F    YT 
Sbjct: 402  GEIFVARPNMLSSRSQPYHRLNISASDGGGLRSTHDAEVFISVIDATQRPPIFDKPRYTY 461

Query: 261  LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT 320
              +E V +N  +G     V A  ++ G    + Y +    Y+G+ D    IDP SG +  
Sbjct: 462  YVKEDVKKNTVVG----TVSATSSNSGSRGSIRYFI----YSGDPDGYFAIDPVSGNIRV 513

Query: 321  SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380
            +  LD ET+ +  L + AT  GDPP                    F      + + E+  
Sbjct: 514  ASTLDHETKPQVLLNIQAT-SGDPPAYGHTQVNIDIEDVNDNPPEFESSTVRISVPENVE 572

Query: 381  PGTPVVTLTATDADE--DNRLHYEIT--GGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436
             G+P+    A D D      + Y ++  G  T   FSI S++G   +++A+PLD++  +R
Sbjct: 573  IGSPLYAANAHDKDSGMSGVITYRLSNNGPATGNLFSIDSRSGH--LSLARPLDYETVQR 630

Query: 437  YVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494
            + L V+A+DSG    S    + + + D N+ APVFE + Y   V E  P  + ++ V+A 
Sbjct: 631  HTLIVTASDSGIPSLSTNLTILVEVQDVNDNAPVFERSEYAIKVSESTPSNSQIMQVTAV 690

Query: 495  DSDVGINAQITYSL---------SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
            D+D G NA++TY +             S  + A+  + F I P +G I     LDRE   
Sbjct: 691  DADTGNNARLTYRILGDDQRTRTGKSSSKASEANTPEIFGIFPNSGWIYLRTKLDREDQE 750

Query: 546  GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
             Y +TV   D GVP+L+ TT V +SV+D NDN P+F +QLY   I E+   G+ +  + A
Sbjct: 751  RYNITVIVSDNGVPTLTATTHVIVSVLDANDNNPIFAKQLYEFQIEENMRRGSVIGLITA 810

Query: 606  TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
            TDAD G+N  + Y L P +    SF I+P SG I T   LDRE+ + +DL   A D GTP
Sbjct: 811  TDADAGINAVVRYSLIPSNT---SFQINPISGEITTRDRLDRETKSIYDLVVEARDQGTP 867

Query: 666  PQSSTVIVHIKIEDIND-SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
             +SS V + IKI D+ND SP + +       + E  PIGT +  +RA D D G NA + Y
Sbjct: 868  YRSSRVSIKIKILDVNDNSPEIVDPQEDVVSVREEQPIGTEVVRVRAIDRDYGVNASITY 927

Query: 725  SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVE 781
            SI  G DS+   + T        + T   LD+E  +  Y L + A     PP      + 
Sbjct: 928  SILKGRDSDGHGMFTID-PITGLIRTKASLDHEE-KTIYRLAVAATDNGKPPRQTVRLLR 985

Query: 782  ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANL 839
            I V D+NDN P      ++F   +D   VG    + +   +    L+  I S N+ ++
Sbjct: 986  IEVLDLNDNRPTFTSSSLVFRLRED---VGVGHVIGSISGNEQSDLENLITSSNDLHI 1040



 Score =  327 bits (804), Expect = 2e-87
 Identities = 274/906 (30%), Positives = 430/906 (47%), Gaps = 80/906 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I VLD ND+ P F        +RE    G  + ++   +Q   +N  +  + +L    T
Sbjct: 985  RIEVLDLNDNRPTFTSSSLVFRLREDVGVGHVIGSISGNEQSDLENL-ITSSNDLHITYT 1043

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            L P              +  F ID  SG L+   SLDRE+ + Y + ++A D  S  ++ 
Sbjct: 1044 LTP--------LTNDIAEGAFDIDRNSGKLVVARSLDREQQSEYRMEIRALD-TSASNNP 1094

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             SS  T+ + I D NDN P++      V + ED +V    V+    ATD D G N+ I+Y
Sbjct: 1095 QSSAVTVKIEIADVNDNPPKWPSDPMNVYISEDAAV--GSVVFNFTATDNDSGTNAEIKY 1152

Query: 190  AIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS--PSRSNTTQLL- 244
             I    T  +  FSIDSL+G ++L+  LDYE+ + + L+++A D  S    R  T+    
Sbjct: 1153 NISKPATAQKEFFSIDSLTGSLTLLAPLDYEETKEFLLIVQATDQSSNVTERMTTSATAR 1212

Query: 245  INIRDVNDNAPRFYTSLFQES---VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
            I + DVNDN+P+F     Q++   VS+++ + + +  V A D D G N  + Y    K  
Sbjct: 1213 IMVTDVNDNSPKFVVPQAQDTTVYVSDSMEVNHIVSHVVAIDRDSGENGRVVY----KIV 1268

Query: 302  TGNVDLPITIDPRSGWV---------YTSGQLDRETQAKYQLLVTATDGGDP-PRSATAT 351
            +GN D    IDP +G+V         + +         +Y L++TATD G P  + A  T
Sbjct: 1269 SGNEDERFAIDPDTGFVKLAKPFSSNFIADNSKNSITGRYNLVITATDQGTPRSKEAKIT 1328

Query: 352  XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTR 409
                          F+   Y + + E+ P G+ VV ++A   +++    L YEI  G   
Sbjct: 1329 IQVVIQNTSNNPPRFLESVYHINITENVPTGSFVVRVSAKSYNDNGNANLTYEIPKGVGD 1388

Query: 410  GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD-------SGGRS------DTAMVQ 456
              F + S   RG++T     D + +  Y + +  T+       + G S      D A + 
Sbjct: 1389 DHFVVDSV--RGIVTTRGTFDRESKDMYTVPIYVTEQNRFKSAASGTSKDMSQFDVATLV 1446

Query: 457  INITDANNYAPVF-ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515
            + ITD N++AP F   + Y  +V E++ + + +  V A+D+D G+N +ITYS+S      
Sbjct: 1447 VRITDVNDHAPEFLPGSCYPLAVPENSEL-SVIHTVVASDADEGLNGEITYSISG----- 1500

Query: 516  AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDV 574
               +   +F I+  TGA+T  + LDRE  + Y+L +TA+D G P S     ++ + V D 
Sbjct: 1501 --GNIGNKFSIDMNTGALTA-RPLDREIHARYVLQITAQDRGSPTSHQGHCNITVRVEDE 1557

Query: 575  NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634
            NDN+P F+ Q Y A I EDA +GT+V  V A DAD+G+N RI Y L   +  E  F ID 
Sbjct: 1558 NDNDPKFELQKYIATIDEDAPIGTTVLTVKAVDADIGINARIVYSL--ANVTEWLFDIDS 1615

Query: 635  ASGVIRTNKALDRESVATHDLKAVAIDGGT-PPQSSTVIVHIKIEDINDSPPVFESDCLT 693
             SGVI T    DRE  + ++   VA DGG    +S +V V + I D+ND+ PVF+     
Sbjct: 1616 KSGVITTAGHFDRERQSIYNFMVVATDGGRYNARSQSVQVQVIIADVNDNKPVFDKYPFK 1675

Query: 694  FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753
              I      G T+  I A D D+G N  + YS+    ++  F +    G+    L     
Sbjct: 1676 EQIGALVQPGQTLLHISATDVDQGSNGEIVYSLNDNPNNAKFRINPNTGA----LSATQS 1731

Query: 754  LDYESPRKKY-ELVIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYK-DCFPV 810
            L  E+ R  + E+  R   +PP      +E+ V D+    P +K FQ   N+YK +    
Sbjct: 1732 LASENGRLLHIEVTARDKGNPPQVATGLIELRVGDLQQELPALK-FQ--NNSYKVNLVEN 1788

Query: 811  GPFGRVPAY-DADVTD----KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATM 865
             P G+   + +A  +D    K+ Y   SGN      ++  TG + +    N +  + + +
Sbjct: 1789 TPIGQTVLHLNAVRSDGRRQKIIYSFGSGNEDGTFSIDAVTGEVKIRNSHNLDYERFSRL 1848

Query: 866  EVSVTD 871
                 D
Sbjct: 1849 NTEGID 1854



 Score =  317 bits (779), Expect = 2e-84
 Identities = 246/809 (30%), Positives = 387/809 (47%), Gaps = 71/809 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            Q+ + + +++ P F    Y  ++ E   +G+ V+ + A   +   NA + Y I     D 
Sbjct: 1330 QVVIQNTSNNPPRFLESVYHINITENVPTGSFVVRVSAKSYNDNGNANLTYEIPKGVGD- 1388

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ------A 123
                              D F +D   G + TR + DRE    YTV +  T+Q      A
Sbjct: 1389 ------------------DHFVVDSVRGIVTTRGTFDRESKDMYTVPIYVTEQNRFKSAA 1430

Query: 124  SPVSDRLSS--TATIHVNIIDDNDNYPQFSEKT-YTVSVDEDISVTDNPVIAKIKATDAD 180
            S  S  +S    AT+ V I D ND+ P+F   + Y ++V E+  ++   VI  + A+DAD
Sbjct: 1431 SGTSKDMSQFDVATLVVRITDVNDHAPEFLPGSCYPLAVPENSELS---VIHTVVASDAD 1487

Query: 181  VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP-SRSN 239
             G N  I Y+I GGN   +FSID  +G ++  + LD E    Y L I AQD GSP S   
Sbjct: 1488 EGLNGEITYSISGGNIGNKFSIDMNTGALT-ARPLDREIHARYVLQITAQDRGSPTSHQG 1546

Query: 240  TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
               + + + D NDN P+F    +  ++ E+ PIG +++ V+A DAD G+NA + Y++ + 
Sbjct: 1547 HCNITVRVEDENDNDPKFELQKYIATIDEDAPIGTTVLTVKAVDADIGINARIVYSLANV 1606

Query: 300  DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD-PPRSATATXXXXXXX 358
                  +    ID +SG + T+G  DRE Q+ Y  +V ATDGG    RS +         
Sbjct: 1607 -----TEWLFDIDSKSGVITTAGHFDRERQSIYNFMVVATDGGRYNARSQSVQVQVIIAD 1661

Query: 359  XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITS 416
                   F    ++ ++     PG  ++ ++ATD D+  +  + Y +       +F I  
Sbjct: 1662 VNDNKPVFDKYPFKEQIGALVQPGQTLLHISATDVDQGSNGEIVYSLNDNPNNAKFRINP 1721

Query: 417  QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSD--TAMVQINITDANNYAPV--FENA 472
              G   ++  Q L  +  R   + V+A D G      T ++++ + D     P   F+N 
Sbjct: 1722 NTGA--LSATQSLASENGRLLHIEVTARDKGNPPQVATGLIELRVGDLQQELPALKFQNN 1779

Query: 473  PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
             Y  ++ E+ PIG TVL ++A  SD G   +I YS  S   NE     D  F I+  TG 
Sbjct: 1780 SYKVNLVENTPIGQTVLHLNAVRSD-GRRQKIIYSFGS--GNE-----DGTFSIDAVTGE 1831

Query: 533  --ITTNKLLDRETMS-----GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585
              I  +  LD E  S     G  L   AR  G P L     +++ + D NDN P F QQ 
Sbjct: 1832 VKIRNSHNLDYERFSRLNTEGIDLVAVARTDGSPLLYGYCSIKVVLQDENDNAPRFTQQQ 1891

Query: 586  YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA-SGVIRTNKA 644
            Y+A++ E    G  V +V A D D G N  I Y +      + +F+I+PA SG+++TN  
Sbjct: 1892 YSASVWEGNNKGEFVIKVNAFDTDQGSNAHILYHI-VDGNHDNAFIIEPAFSGIVKTNIV 1950

Query: 645  LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
            LDRE    + LK +A D G P  + T  +++ + D+ND+ P F  + +   +SE + +GT
Sbjct: 1951 LDREIRDKYKLKVIATDEGVPQMTGTATINVNVVDVNDNQPTFPPNSV-ISVSEATTVGT 2009

Query: 705  TIGEIRAHDPDEGPNAVVHYSIKGGDDSNS-FSLETRQGSDKAELVTMVDLDYESPRKKY 763
             +  I A+D D  P     +     +D+ S FS++   G    +++ +  LDYE+ R ++
Sbjct: 2010 VLTSITANDVDTNPPLTYSFGDSPDEDAKSYFSIDRYSG----KVILIKPLDYEA-RHEF 2064

Query: 764  ELVIRAASPPLWNDVRVEILVTDVNDNAP 792
            +L I A+         + + VTDVNDN P
Sbjct: 2065 QLRILASDSAHVARTLLTVRVTDVNDNPP 2093



 Score =  294 bits (721), Expect = 3e-77
 Identities = 262/937 (27%), Positives = 433/937 (46%), Gaps = 98/937 (10%)

Query: 8    HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
            H  ++VLD ND++P+F  Q YE  + E    G+ +  + ATD D G NA V Y+  L+ +
Sbjct: 771  HVIVSVLDANDNNPIFAKQLYEFQIEENMRRGSVIGLITATDADAGINAVVRYS--LIPS 828

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
            +T                    F+I+  SG + TR  LDRE  + Y ++V+A DQ +P  
Sbjct: 829  NT-------------------SFQINPISGEITTRDRLDRETKSIYDLVVEARDQGTPYR 869

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
               SS  +I + I+D NDN P+  + +   VSV E+  +     + +++A D D G N++
Sbjct: 870  ---SSRVSIKIKILDVNDNSPEIVDPQEDVVSVREEQPI--GTEVVRVRAIDRDYGVNAS 924

Query: 187  IRYAIIGG---NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
            I Y+I+ G   +    F+ID ++G +    +LD+E+   YRL + A D G P R     L
Sbjct: 925  ITYSILKGRDSDGHGMFTIDPITGLIRTKASLDHEEKTIYRLAVAATDNGKPPRQTVRLL 984

Query: 244  LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN-------AELTYTM 296
             I + D+NDN P F +S     + E+V +G+ I  +   +  +  N         +TYT+
Sbjct: 985  RIEVLDLNDNRPTFTSSSLVFRLREDVGVGHVIGSISGNEQSDLENLITSSNDLHITYTL 1044

Query: 297  TDKDYTGNV-DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA--TDGGDPPRSATATXX 353
            T    T ++ +    ID  SG +  +  LDRE Q++Y++ + A  T   + P+S+  T  
Sbjct: 1045 T--PLTNDIAEGAFDIDRNSGKLVVARSLDREQQSEYRMEIRALDTSASNNPQSSAVTVK 1102

Query: 354  XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGR 411
                        +      V ++ED   G+ V   TATD D   +  + Y I+   T  +
Sbjct: 1103 IEIADVNDNPPKWPSDPMNVYISEDAAVGSVVFNFTATDNDSGTNAEIKYNISKPATAQK 1162

Query: 412  FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR-----SDTAMVQINITDANNYA 466
               +  +  G +T+  PLD+++ + ++L V ATD         + +A  +I +TD N+ +
Sbjct: 1163 EFFSIDSLTGSLTLLAPLDYEETKEFLLIVQATDQSSNVTERMTTSATARIMVTDVNDNS 1222

Query: 467  PVF---ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523
            P F   +    T  V +   +   V  V A D D G N ++ Y + S   NE     D++
Sbjct: 1223 PKFVVPQAQDTTVYVSDSMEVNHIVSHVVAIDRDSGENGRVVYKIVS--GNE-----DER 1275

Query: 524  FVINPQTGAI------TTNKLLD--RETMSG-YLLTVTARDGGVP-SLSDTTDVEISVVD 573
            F I+P TG +      ++N + D  + +++G Y L +TA D G P S      +++ + +
Sbjct: 1276 FAIDPDTGFVKLAKPFSSNFIADNSKNSITGRYNLVITATDQGTPRSKEAKITIQVVIQN 1335

Query: 574  VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633
             ++N P F + +Y  NI E+   G+ V +V A   +   N  + YE+ PK   +  FV+D
Sbjct: 1336 TSNNPPRFLESVYHINITENVPTGSFVVRVSAKSYNDNGNANLTYEI-PKGVGDDHFVVD 1394

Query: 634  PASGVIRTNKALDRES--------VATHDLKAVAIDGGTP---PQSSTVIVHIKIEDIND 682
               G++ T    DRES          T   +  +   GT     Q     + ++I D+ND
Sbjct: 1395 SVRGIVTTRGTFDRESKDMYTVPIYVTEQNRFKSAASGTSKDMSQFDVATLVVRITDVND 1454

Query: 683  SPPVF-ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741
              P F    C    + ENS + + I  + A D DEG N  + YSI GG+  N FS++   
Sbjct: 1455 HAPEFLPGSCYPLAVPENSEL-SVIHTVVASDADEGLNGEITYSISGGNIGNKFSIDMNT 1513

Query: 742  GSDKAELVTMVDLDYESPRKKYELVIRA---ASPPL-WNDVRVEILVTDVNDNAPVMKDF 797
            G+     +T   LD E    +Y L I A    SP        + + V D NDN P  +  
Sbjct: 1514 GA-----LTARPLDREI-HARYVLQITAQDRGSPTSHQGHCNITVRVEDENDNDPKFELQ 1567

Query: 798  QIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQ 854
            + I    +D  P+G     V A DAD  +  ++ Y  L+     L  ++  +G +T +  
Sbjct: 1568 KYIATIDEDA-PIGTTVLTVKAVDADIGINARIVYS-LANVTEWLFDIDSKSGVITTAGH 1625

Query: 855  LNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEM 891
             +     +    V  TDG         + V++I  ++
Sbjct: 1626 FDRERQSIYNFMVVATDGGRYNARSQSVQVQVIIADV 1662



 Score =  286 bits (701), Expect = 7e-75
 Identities = 228/753 (30%), Positives = 356/753 (47%), Gaps = 54/753 (7%)

Query: 153 KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQM-QFSIDSLSGDVSL 211
           K  TV V   +      V + + ATD D G N+ + Y +  G  ++ +F I S +G+V +
Sbjct: 240 KLGTVMVRRSVDQPPVAVHSDVSATDPDCGVNAMVNYTLGEGYKKITEFEIRSSTGEVCI 299

Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271
              LDYE   SY   I A D G    S T  + I + DVNDN P FY   +  S+ E++P
Sbjct: 300 AAELDYETRNSYEFPIIATDRG--GLSTTAMVKIQLTDVNDNRPTFYPREYNVSLRESMP 357

Query: 272 ----IGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS--GQLD 325
               +   +V + A D+D G    ++Y +      GN      +D  +G ++ +    L 
Sbjct: 358 TNSLLSTPVVVIVATDSDSGSFGTISYRIV----AGNEAGIFRMDRLTGEIFVARPNMLS 413

Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
             +Q  ++L ++A+DGG    +  A               F   +Y   + ED    T V
Sbjct: 414 SRSQPYHRLNISASDGGGLRSTHDAEVFISVIDATQRPPIFDKPRYTYYVKEDVKKNTVV 473

Query: 386 VTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443
            T++AT ++  +R  + Y I  G+  G F+I   +G   I VA  LD + + + +L + A
Sbjct: 474 GTVSATSSNSGSRGSIRYFIYSGDPDGYFAIDPVSGN--IRVASTLDHETKPQVLLNIQA 531

Query: 444 TDSGGRS-DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502
           T     +     V I+I D N+  P FE++    SV E+  IG+ +   +A D D G++ 
Sbjct: 532 TSGDPPAYGHTQVNIDIEDVNDNPPEFESSTVRISVPENVEIGSPLYAANAHDKDSGMSG 591

Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
            ITY LS+  +  A  +    F I+ ++G ++  + LD ET+  + L VTA D G+PSLS
Sbjct: 592 VITYRLSN--NGPATGN---LFSIDSRSGHLSLARPLDYETVQRHTLIVTASDSGIPSLS 646

Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-- 620
               + + V DVNDN PVF++  Y   + E     + + QV A DAD G N R+ Y +  
Sbjct: 647 TNLTILVEVQDVNDNAPVFERSEYAIKVSESTPSNSQIMQVTAVDADTGNNARLTYRILG 706

Query: 621 -DPKDREEGS------------FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
            D + R   S            F I P SG I     LDRE    +++  +  D G P  
Sbjct: 707 DDQRTRTGKSSSKASEANTPEIFGIFPNSGWIYLRTKLDREDQERYNITVIVSDNGVPTL 766

Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
           ++T  V + + D ND+ P+F      F I EN   G+ IG I A D D G NAVV YS+ 
Sbjct: 767 TATTHVIVSVLDANDNNPIFAKQLYEFQIEENMRRGSVIGLITATDADAGINAVVRYSLI 826

Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILV 784
               + SF +    G    E+ T   LD E+ +  Y+LV+ A    +P   + V ++I +
Sbjct: 827 --PSNTSFQINPISG----EITTRDRLDRET-KSIYDLVVEARDQGTPYRSSRVSIKIKI 879

Query: 785 TDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILSGNNAN--- 838
            DVNDN+P + D Q    + ++  P+G    RV A D D  V   + Y IL G +++   
Sbjct: 880 LDVNDNSPEIVDPQEDVVSVREEQPIGTEVVRVRAIDRDYGVNASITYSILKGRDSDGHG 939

Query: 839 LILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
           +  ++  TG +     L+     +  + V+ TD
Sbjct: 940 MFTIDPITGLIRTKASLDHEEKTIYRLAVAATD 972



 Score =  282 bits (691), Expect = 1e-73
 Identities = 246/828 (29%), Positives = 379/828 (45%), Gaps = 80/828 (9%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            +  Q+ + D ND+ PVF+   ++  +      G T+L + ATD D G N E+ Y++    
Sbjct: 1653 VQVQVIIADVNDNKPVFDKYPFKEQIGALVQPGQTLLHISATDVDQGSNGEIVYSLN--- 1709

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
             D  NP +A              FRI+  +GAL    SL  E      + V A D+ +P 
Sbjct: 1710 -D--NPNNAK-------------FRINPNTGALSATQSLASENGRLLHIEVTARDKGNPP 1753

Query: 127  SDRLSSTATIHVNIIDDNDNYP--QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184
                 +T  I + + D     P  +F   +Y V++ E+  +     +  + A  +D G  
Sbjct: 1754 Q---VATGLIELRVGDLQQELPALKFQNNSYKVNLVENTPI--GQTVLHLNAVRSD-GRR 1807

Query: 185  SAIRYAIIGGNTQMQFSIDSLSGDVSLVKT--LDYEQ-----VRSYRLVIRAQDGGSPSR 237
              I Y+   GN    FSID+++G+V +  +  LDYE+          LV  A+  GSP  
Sbjct: 1808 QKIIYSFGSGNEDGTFSIDAVTGEVKIRNSHNLDYERFSRLNTEGIDLVAVARTDGSPLL 1867

Query: 238  SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297
                 + + ++D NDNAPRF    +  SV E    G  +++V A+D D+G NA + Y + 
Sbjct: 1868 YGYCSIKVVLQDENDNAPRFTQQQYSASVWEGNNKGEFVIKVNAFDTDQGSNAHILYHIV 1927

Query: 298  DKDYTGNVDLPITIDPR-SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
            D    GN D    I+P  SG V T+  LDRE + KY+L V ATD G P  + TAT     
Sbjct: 1928 D----GNHDNAFIIEPAFSGIVKTNIVLDREIRDKYKLKVIATDEGVPQMTGTATINVNV 1983

Query: 357  XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG---NTRGRFS 413
                     F P    + ++E    GT + ++TA D D +  L Y        + +  FS
Sbjct: 1984 VDVNDNQPTFPPNSV-ISVSEATTVGTVLTSITANDVDTNPPLTYSFGDSPDEDAKSYFS 2042

Query: 414  ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAP 473
            I   +G+  + + +PLD++    + L + A+DS   + T ++ + +TD N+  P F+   
Sbjct: 2043 IDRYSGK--VILIKPLDYEARHEFQLRILASDSAHVART-LLTVRVTDVNDNPPQFQQIT 2099

Query: 474  YTASV-------FEDAPIGTTV---LVVSATDSDVGINAQITYSLSSEISNEAVAHH--- 520
            Y A +       F++    + +   L+   TDS+  I      +  S+  N A   +   
Sbjct: 2100 YHAMLNGTNFPRFKNPGTHSNISFSLITDDTDSNSNIAIIAVNATDSDSENNAAIRYTII 2159

Query: 521  --DQQFVINPQTGAITTNKLLDRETMSGYL-LTVTARDGGVPSLSDTTDVEISVVDVNDN 577
                 F I+  TG +  N      T SG L LT+TA D GVP LS +T V + +   +  
Sbjct: 2160 PPSIGFAIDALTGQLFVNMSQVHRTRSGTLYLTITATDSGVPPLSSSTTVRLEMKSKSKA 2219

Query: 578  EPVFKQQLYTANIMEDALVGTSVSQV--GATDADVGLNGRIHYELDPKDREEGSFVIDPA 635
             P F Q  Y  +I EDA  G+ ++ +   A    V ++  I +E+     ++  F I   
Sbjct: 2220 NPHFIQSQYRLSINEDAPTGSVITNLIPKAIAEQVDVSSSIAFEI-IDGNDDNCFEISYP 2278

Query: 636  SGVIRTNKALDRESVATHDLKAVAIDGGTP------PQSSTVIVHIKIEDINDSPPVFES 689
            SG I   K+LDRE    ++L+ V  + G          SS + V I +ED ND+ P F+ 
Sbjct: 2279 SGAILLVKSLDREKTDYYELRLVVTEPGATMMYKGMNMSSAIRVTITVEDANDNAPEFQP 2338

Query: 690  DCLTFYISENSPIGTTIGEIRAHDPD--EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747
                  ISE +PI  +IG+I A D D    PN+ V Y I  G+D   FS++   G     
Sbjct: 2339 GPYEVAISETAPIKYSIGQISAVDADLLNSPNSEVVYQIVSGNDGGWFSIDLITGL---- 2394

Query: 748  LVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE---ILVTDVNDNAP 792
            L    +LDY+    ++ LVIRA    +     V    I +TD NDN P
Sbjct: 2395 LYINNNLDYDRGPTQFNLVIRACDSHVLPKCSVHPFVINLTDENDNEP 2442



 Score =  266 bits (653), Expect = 5e-69
 Identities = 256/917 (27%), Positives = 410/917 (44%), Gaps = 93/917 (10%)

Query: 10   QINVLDCNDHSP-VFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68
            +I +LD ND+SP + + Q+   SVRE    GT V+ ++A D+D G NA + Y+I      
Sbjct: 876  KIKILDVNDNSPEIVDPQEDVVSVREEQPIGTEVVRVRAIDRDYGVNASITYSI------ 929

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
             L   D+             +F ID  +G + T+ASLD E+   Y + V ATD   P   
Sbjct: 930  -LKGRDSDG---------HGMFTIDPITGLIRTKASLDHEEKTIYRLAVAATDNGKPPRQ 979

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD------VG 182
               +   + + ++D NDN P F+  +    + ED+ V    VI  I   +          
Sbjct: 980  ---TVRLLRIEVLDLNDNRPTFTSSSLVFRLREDVGV--GHVIGSISGNEQSDLENLITS 1034

Query: 183  ANSA-IRYAIIGGNTQMQ---FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-- 236
            +N   I Y +      +    F ID  SG + + ++LD EQ   YR+ IRA D  + +  
Sbjct: 1035 SNDLHITYTLTPLTNDIAEGAFDIDRNSGKLVVARSLDREQQSEYRMEIRALDTSASNNP 1094

Query: 237  RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
            +S+   + I I DVNDN P++ +      +SE+  +G  +    A D D G NAE+ Y +
Sbjct: 1095 QSSAVTVKIEIADVNDNPPKWPSDPMNVYISEDAAVGSVVFNFTATDNDSGTNAEIKYNI 1154

Query: 297  TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-----PRSATAT 351
            + K  T   +   +ID  +G +     LD E   ++ L+V ATD           SATA 
Sbjct: 1155 S-KPATAQKEF-FSIDSLTGSLTLLAPLDYEETKEFLLIVQATDQSSNVTERMTTSATAR 1212

Query: 352  XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT-LTATDAD--EDNRLHYEITGGNT 408
                              Q       D      +V+ + A D D  E+ R+ Y+I  GN 
Sbjct: 1213 IMVTDVNDNSPKFVVPQAQDTTVYVSDSMEVNHIVSHVVAIDRDSGENGRVVYKIVSGNE 1272

Query: 409  RGRFSITSQNGRGLITVAQPL--DFKQER-------RYVLTVSATDSGG-RSDTAMV--Q 456
              RF+I    G   + +A+P   +F  +        RY L ++ATD G  RS  A +  Q
Sbjct: 1273 DERFAIDPDTG--FVKLAKPFSSNFIADNSKNSITGRYNLVITATDQGTPRSKEAKITIQ 1330

Query: 457  INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA 516
            + I + +N  P F  + Y  ++ E+ P G+ V+ VSA   +   NA +TY +   +    
Sbjct: 1331 VVIQNTSNNPPRFLESVYHINITENVPTGSFVVRVSAKSYNDNGNANLTYEIPKGVG--- 1387

Query: 517  VAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTV---------TARDGGVPSLS--DTT 565
                D  FV++   G +TT    DRE+   Y + +         +A  G    +S  D  
Sbjct: 1388 ----DDHFVVDSVRGIVTTRGTFDRESKDMYTVPIYVTEQNRFKSAASGTSKDMSQFDVA 1443

Query: 566  DVEISVVDVNDNEPVFKQ-QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624
             + + + DVND+ P F     Y   + E++ +   +  V A+DAD GLNG I Y +   +
Sbjct: 1444 TLVVRITDVNDHAPEFLPGSCYPLAVPENSELSV-IHTVVASDADEGLNGEITYSISGGN 1502

Query: 625  REEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDS 683
                 F ID  +G + T + LDRE  A + L+  A D G+P        + +++ED ND+
Sbjct: 1503 IGN-KFSIDMNTGAL-TARPLDREIHARYVLQITAQDRGSPTSHQGHCNITVRVEDENDN 1560

Query: 684  PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
             P FE       I E++PIGTT+  ++A D D G NA + YS+    +   F ++++ G 
Sbjct: 1561 DPKFELQKYIATIDEDAPIGTTVLTVKAVDADIGINARIVYSLANVTEW-LFDIDSKSGV 1619

Query: 744  DKAELVTMVDLDYESPRKKYELVIRAASPPLWN----DVRVEILVTDVNDNAPVMKDFQI 799
                + T    D E  +  Y  ++ A     +N     V+V++++ DVNDN PV   +  
Sbjct: 1620 ----ITTAGHFDRER-QSIYNFMVVATDGGRYNARSQSVQVQVIIADVNDNKPVFDKYPF 1674

Query: 800  IFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNT 857
                     P      + A D D     ++ Y +    N     +N  TG+++ +  L +
Sbjct: 1675 KEQIGALVQPGQTLLHISATDVDQGSNGEIVYSLNDNPNNAKFRINPNTGALSATQSLAS 1734

Query: 858  NVPKLATMEVSVTDGVN 874
               +L  +EV+  D  N
Sbjct: 1735 ENGRLLHIEVTARDKGN 1751



 Score =  213 bits (521), Expect = 4e-53
 Identities = 241/897 (26%), Positives = 384/897 (42%), Gaps = 85/897 (9%)

Query: 10   QINVLDCNDHSPVFEMQQ--YEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
            ++ V D     P  + Q   Y+ ++ E    G TVL L A   D G+  ++ Y+      
Sbjct: 1761 ELRVGDLQQELPALKFQNNSYKVNLVENTPIGQTVLHLNAVRSD-GRRQKIIYSFGSGNE 1819

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
            D     DA          +++   +D    + L    +D   VAR       TD  SP+ 
Sbjct: 1820 DGTFSIDAVTGEVK----IRNSHNLDYERFSRLNTEGIDLVAVAR-------TD-GSPL- 1866

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
              L    +I V + D+NDN P+F+++ Y+ SV E  +  +   + K+ A D D G+N+ I
Sbjct: 1867 --LYGYCSIKVVLQDENDNAPRFTQQQYSASVWEGNNKGE--FVIKVNAFDTDQGSNAHI 1922

Query: 188  RYAIIGGNTQMQFSID-SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
             Y I+ GN    F I+ + SG V     LD E    Y+L + A D G P  + T  + +N
Sbjct: 1923 LYHIVDGNHDNAFIIEPAFSGIVKTNIVLDREIRDKYKLKVIATDEGVPQMTGTATINVN 1982

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            + DVNDN P F  +    SVSE   +G  +  + A D D   N  LTY+  D     +  
Sbjct: 1983 VVDVNDNQPTFPPNSVI-SVSEATTVGTVLTSITANDVD--TNPPLTYSFGDSP-DEDAK 2038

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG----------------DPPRSATA 350
               +ID  SG V     LD E + ++QL + A+D                  +PP+    
Sbjct: 2039 SYFSIDRYSGKVILIKPLDYEARHEFQLRILASDSAHVARTLLTVRVTDVNDNPPQFQQI 2098

Query: 351  TXXXXXXXXXXXXXXFMPGQYE---VELAEDEPPGTP---VVTLTATDADEDNRLHYEIT 404
            T                PG +      L  D+        ++ + ATD+D +N      T
Sbjct: 2099 TYHAMLNGTNFPRFK-NPGTHSNISFSLITDDTDSNSNIAIIAVNATDSDSENNAAIRYT 2157

Query: 405  GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDA 462
                   F+I +  G+  + ++Q    +    Y LT++ATDSG    S +  V++ +   
Sbjct: 2158 IIPPSIGFAIDALTGQLFVNMSQVHRTRSGTLY-LTITATDSGVPPLSSSTTVRLEMKSK 2216

Query: 463  NNYAPVFENAPYTASVFEDAPIGTTV--LVVSATDSDVGINAQITYSLSSEISNEAVAHH 520
            +   P F  + Y  S+ EDAP G+ +  L+  A    V +++ I + +          + 
Sbjct: 2217 SKANPHFIQSQYRLSINEDAPTGSVITNLIPKAIAEQVDVSSSIAFEIID-------GND 2269

Query: 521  DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP------SLSDTTDVEISVVDV 574
            D  F I+  +GAI   K LDRE    Y L +   + G        ++S    V I+V D 
Sbjct: 2270 DNCFEISYPSGAILLVKSLDREKTDYYELRLVVTEPGATMMYKGMNMSSAIRVTITVEDA 2329

Query: 575  NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV--GLNGRIHYELDPKDREEGSFVI 632
            NDN P F+   Y   I E A +  S+ Q+ A DAD+    N  + Y++     + G F I
Sbjct: 2330 NDNAPEFQPGPYEVAISETAPIKYSIGQISAVDADLLNSPNSEVVYQI-VSGNDGGWFSI 2388

Query: 633  DPASGVIRTNKALDRESVATH-DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691
            D  +G++  N  LD +   T  +L   A D    P+ S     I + D ND+ P F    
Sbjct: 2389 DLITGLLYINNNLDYDRGPTQFNLVIRACDSHVLPKCSVHPFVINLTDENDNEPQFPVPE 2448

Query: 692  LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751
               ++ EN PIG +I   RA D D G    V+YSI     S   S++      K + V+ 
Sbjct: 2449 YLEFVGENEPIGISIFTARATDMDRGEYGRVNYSIDNAMTSGYSSVDDGWKLFKVDSVSG 2508

Query: 752  V-----DLDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAP--VMKDFQIIFNN 803
            V       DYE  + +Y   +RA  +      V+V I++   ++ +P    + ++ I   
Sbjct: 2509 VINSNAVFDYEE-KNRYSFTLRATDTGGKSKTVKVRIMIESRDEFSPQFTERTYRFILKT 2567

Query: 804  -YKDCFPVG-PFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
                  PVG   G V A D D     ++ Y++ + +      +N TTG++ +  +L+
Sbjct: 2568 PDTGHLPVGYVVGHVTATDRDRGPDGRIVYQLTTQH--PYFKMNRTTGAILVKKKLD 2622



 Score =  179 bits (435), Expect = 1e-42
 Identities = 169/598 (28%), Positives = 266/598 (44%), Gaps = 59/598 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVR-----EGASSGT-TVLTLKATDQDIGKNAEVEYTIEL 64
            + V D ND+ P F+   Y A +         + GT + ++      D   N+ +   I +
Sbjct: 2083 VRVTDVNDNPPQFQQITYHAMLNGTNFPRFKNPGTHSNISFSLITDDTDSNSNIAI-IAV 2141

Query: 65   VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS-LDREKVARYTVLVKATDQA 123
               D+ +  +A          +   F ID  +G L    S + R +     + + ATD  
Sbjct: 2142 NATDSDSENNAAIRYTIIPPSIG--FAIDALTGQLFVNMSQVHRTRSGTLYLTITATDSG 2199

Query: 124  SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI---SVTDNPVIAKIKATDAD 180
             P    LSS+ T+ + +   +   P F +  Y +S++ED    SV  N +I K  A   D
Sbjct: 2200 VPP---LSSSTTVRLEMKSKSKANPHFIQSQYRLSINEDAPTGSVITN-LIPKAIAEQVD 2255

Query: 181  VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP----- 235
            V  +S+I + II GN    F I   SG + LVK+LD E+   Y L +   + G+      
Sbjct: 2256 V--SSSIAFEIIDGNDDNCFEISYPSGAILLVKSLDREKTDYYELRLVVTEPGATMMYKG 2313

Query: 236  -SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD--EGVNAEL 292
             + S+  ++ I + D NDNAP F    ++ ++SE  PI YSI ++ A DAD     N+E+
Sbjct: 2314 MNMSSAIRVTITVEDANDNAPEFQPGPYEVAISETAPIKYSIGQISAVDADLLNSPNSEV 2373

Query: 293  TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET-QAKYQLLVTATDGGDPPRSATAT 351
             Y +     +GN     +ID  +G +Y +  LD +    ++ L++ A D    P+ +   
Sbjct: 2374 VYQIV----SGNDGGWFSIDLITGLLYINNNLDYDRGPTQFNLVIRACDSHVLPKCSVHP 2429

Query: 352  XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTR 409
                          F   +Y   + E+EP G  + T  ATD D  E  R++Y I    T 
Sbjct: 2430 FVINLTDENDNEPQFPVPEYLEFVGENEPIGISIFTARATDMDRGEYGRVNYSIDNAMTS 2489

Query: 410  GRFSITS-------QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDA 462
            G  S+          +  G+I      D++++ RY  T+ ATD+GG+S T  V+I I   
Sbjct: 2490 GYSSVDDGWKLFKVDSVSGVINSNAVFDYEEKNRYSFTLRATDTGGKSKTVKVRIMIESR 2549

Query: 463  NNYAPVFENAPYTASVFED----APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518
            + ++P F    Y   +        P+G  V  V+ATD D G + +I Y L+++       
Sbjct: 2550 DEFSPQFTERTYRFILKTPDTGHLPVGYVVGHVTATDRDRGPDGRIVYQLTTQ------- 2602

Query: 519  HHDQQFVINPQTGAITTNKLLDRETMS-----GYLLTVTARDGGVPSLSDTTDVEISV 571
                 F +N  TGAI   K LD    S        L VTA  G   SL++ T VEIS+
Sbjct: 2603 --HPYFKMNRTTGAILVKKKLDDVAASLEAGRDISLVVTASSGRQGSLTNMTVVEISI 2658



 Score = 93.1 bits (221), Expect = 1e-16
 Identities = 81/311 (26%), Positives = 142/311 (45%), Gaps = 38/311 (12%)

Query: 1    MSVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEY 60
            M++   I   I V D ND++P F+   YE ++ E A    ++  + A D D+  +   E 
Sbjct: 2314 MNMSSAIRVTITVEDANDNAPEFQPGPYEVAISETAPIKYSIGQISAVDADLLNSPNSEV 2373

Query: 61   TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREK-VARYTVLVKA 119
              ++V+ +     D               F ID  +G L    +LD ++   ++ ++++A
Sbjct: 2374 VYQIVSGN-----DGGW------------FSIDLITGLLYINNNLDYDRGPTQFNLVIRA 2416

Query: 120  TDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA 179
             D  S V  + S    + +N+ D+NDN PQF    Y   V E+  +  +  I   +ATD 
Sbjct: 2417 CD--SHVLPKCSVHPFV-INLTDENDNEPQFPVPEYLEFVGENEPIGIS--IFTARATDM 2471

Query: 180  DVGANSAIRYAIIGGNTQ---------MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ 230
            D G    + Y+I    T            F +DS+SG ++     DYE+   Y   +RA 
Sbjct: 2472 DRGEYGRVNYSIDNAMTSGYSSVDDGWKLFKVDSVSGVINSNAVFDYEEKNRYSFTLRAT 2531

Query: 231  DGGSPSRSNTTQLLINIRDVNDNAPRF----YTSLFQESVSENVPIGYSIVRVQAYDADE 286
            D G  S++   +++I  RD  + +P+F    Y  + +   + ++P+GY +  V A D D 
Sbjct: 2532 DTGGKSKTVKVRIMIESRD--EFSPQFTERTYRFILKTPDTGHLPVGYVVGHVTATDRDR 2589

Query: 287  GVNAELTYTMT 297
            G +  + Y +T
Sbjct: 2590 GPDGRIVYQLT 2600


>UniRef50_UPI00015A7221 Cluster: UPI00015A7221 related cluster; n=1;
            Danio rerio|Rep: UPI00015A7221 UniRef100 entry - Danio
            rerio
          Length = 3995

 Score =  370 bits (910), Expect = e-100
 Identities = 264/900 (29%), Positives = 447/900 (49%), Gaps = 68/900 (7%)

Query: 3    VPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
            V FC   +I + D ND+ P F+  +Y+ S++   + G+ V+ + A D D GKNA+V YT+
Sbjct: 2551 VGFCT-VKIILTDENDNVPQFKASEYDISIQSTVNKGSPVIQIMAYDADEGKNADVTYTV 2609

Query: 63   ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122
            E   AD +                +D+  ++  +G +  + SL   +   +   VKA D 
Sbjct: 2610 E--EADEV---------------TEDIIEVNPFTGVVSVKESLVGLENKIFNFKVKARDG 2652

Query: 123  ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
              P     +S+  + V ++      P+F+E  Y+ S  ED+     P+  +I    AD  
Sbjct: 2653 GFPF---YNSSVPVQVKVVPPEIILPRFTEPLYSFSASEDL-----PIGYEIGTVKAD-- 2702

Query: 183  ANSAIRYAIIGGNT-----QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237
            A+  + Y+++ GNT     ++ F+ID   G V L   +D+E+ + Y++ + AQ  G+ + 
Sbjct: 2703 ADMPLIYSLVNGNTLDSNKELSFAIDKDGGTVVLQNNIDHEKTKMYKIDVIAQ--GNHNG 2760

Query: 238  SNTTQLL---INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294
            +N   L+   I ++DVNDN P F    ++  ++EN+P G ++++V A DAD  +N E++Y
Sbjct: 2761 TNVASLVSVHIEVQDVNDNKPMFEADTYKAFLAENLPSGTTVIQVTANDADANINGEVSY 2820

Query: 295  TM-TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSATATX 352
            T+  + D  G++     ID ++GW+ T  + D ET+  ++  V ATD GD   +SA+   
Sbjct: 2821 TLEPESDDIGDM---FAIDSQTGWITTLKEADSETKQLHRFFVVATDHGDALKQSASVLV 2877

Query: 353  XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTR 409
                         F    Y+  + E+  PG  +VTLT  D D   E+ ++   IT G+  
Sbjct: 2878 EVTLTDENDNPPQFTEELYQGSILENSRPGENIVTLTTADKDVSAENRQIVCYITDGDPL 2937

Query: 410  GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVF 469
            G+FS+T+      +    PLD + + +Y L + ATD G    +A V++++ D N+ +P  
Sbjct: 2938 GQFSVTAVGEEWTVISKSPLDREDKDKYTLKIIATD-GRFQTSANVEVHVLDLNDNSPFC 2996

Query: 470  ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
            E   YT +V E++  G  +L +SA+D D+G N Q++++L           +  +F ++P+
Sbjct: 2997 EQLQYTEAVMENSSSGKVILKISASDPDIGTNGQVSFTLHGP--------NADKFHLDPK 3048

Query: 530  TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589
            TG + T  +LDRE    Y L V A DGG    S   DV + V D+NDN P F    Y   
Sbjct: 3049 TGELFTLAVLDREREKEYDLVVKATDGG--GRSCQADVTLMVQDMNDNPPQFSTSHYEVT 3106

Query: 590  IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES 649
            + ++  + T ++ + A D D G+N  + Y L   D   G F +D  SGV+R  ++L  E+
Sbjct: 3107 VFDNTTIRTPIAVIYAKDPDTGINSEVRYSLQGAD--SGFFSLDEISGVLRLERSLADET 3164

Query: 650  VATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
             +T+++K  A D G P    S  ++ + +  ++D  P+F S   +  I+E+S +G+ +  
Sbjct: 3165 KSTYEMKVKATDRGLPRHLFSFAMITVHVVILSDYQPLFLSSEYSVQIAESSQVGSEVIS 3224

Query: 709  IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768
            + A   D   N  V YSI  G++   F +    G     L     LD+E  R+ Y  V  
Sbjct: 3225 VSALTKDATENEPVRYSIISGNEDGRFMINPVTGL----LSVKAALDFERCREYYLSVEG 3280

Query: 769  AASPPLWNDVRVEIL-VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTD 825
            A   PL +D+ + I+ +TDVNDN PV           +D  P     +V A D D    +
Sbjct: 3281 ARGKPLLSDIAMVIINITDVNDNPPVFNRSSYSTVIPEDISPGEMALQVRAIDLDGPPNN 3340

Query: 826  KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSV 884
             + Y I+SG+      ++  TG +TL   L+       ++ V   D G   + + +Q++V
Sbjct: 3341 FIIYSIVSGDPKQQFSIDPRTGFITLRSMLDREEITHYSLTVQAADEGDPPLSSAVQVTV 3400



 Score =  365 bits (897), Expect = 1e-98
 Identities = 281/949 (29%), Positives = 453/949 (47%), Gaps = 65/949 (6%)

Query: 2    SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
            +V   +   I V D ND+ P+FE   Y+A + E   SGTTV+ + A D D   N EV YT
Sbjct: 2762 NVASLVSVHIEVQDVNDNKPMFEADTYKAFLAENLPSGTTVIQVTANDADANINGEVSYT 2821

Query: 62   IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121
            +E        PE            + D+F ID ++G + T    D E    +   V ATD
Sbjct: 2822 LE--------PES---------DDIGDMFAIDSQTGWITTLKEADSETKQLHRFFVVATD 2864

Query: 122  QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181
                +    S++  + V + D+NDN PQF+E+ Y  S+ E+    +N  I  +   D DV
Sbjct: 2865 HGDALKQ--SASVLVEVTLTDENDNPPQFTEELYQGSILENSRPGEN--IVTLTTADKDV 2920

Query: 182  GA-NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRS 238
             A N  I   I  G+   QFS+ ++  + +++    LD E    Y L I A DG   + +
Sbjct: 2921 SAENRQIVCYITDGDPLGQFSVTAVGEEWTVISKSPLDREDKDKYTLKIIATDGRFQTSA 2980

Query: 239  NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
            N     +++ D+NDN+P      + E+V EN   G  I+++ A D D G N ++++T+  
Sbjct: 2981 NVE---VHVLDLNDNSPFCEQLQYTEAVMENSSSGKVILKISASDPDIGTNGQVSFTL-- 3035

Query: 299  KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358
              +  N D    +DP++G ++T   LDRE + +Y L+V ATDGG   RS  A        
Sbjct: 3036 --HGPNAD-KFHLDPKTGELFTLAVLDREREKEYDLVVKATDGGG--RSCQADVTLMVQD 3090

Query: 359  XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITS 416
                   F    YEV + ++    TP+  + A D D   ++ + Y + G ++ G FS+  
Sbjct: 3091 MNDNPPQFSTSHYEVTVFDNTTIRTPIAVIYAKDPDTGINSEVRYSLQGADS-GFFSLDE 3149

Query: 417  QNGRGLITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAP 473
             +G  ++ + + L  + +  Y + V ATD G        AM+ +++   ++Y P+F ++ 
Sbjct: 3150 ISG--VLRLERSLADETKSTYEMKVKATDRGLPRHLFSFAMITVHVVILSDYQPLFLSSE 3207

Query: 474  YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
            Y+  + E + +G+ V+ VSA   D   N  + YS+ S   NE     D +F+INP TG +
Sbjct: 3208 YSVQIAESSQVGSEVISVSALTKDATENEPVRYSIIS--GNE-----DGRFMINPVTGLL 3260

Query: 534  TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593
            +    LD E    Y L+V    G  P LSD   V I++ DVNDN PVF +  Y+  I ED
Sbjct: 3261 SVKAALDFERCREYYLSVEGARGK-PLLSDIAMVIINITDVNDNPPVFNRSSYSTVIPED 3319

Query: 594  ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653
               G    QV A D D   N  I Y +   D ++  F IDP +G I     LDRE +  +
Sbjct: 3320 ISPGEMALQVRAIDLDGPPNNFIIYSIVSGDPKQ-QFSIDPRTGFITLRSMLDREEITHY 3378

Query: 654  DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713
             L   A D G PP SS V V + + D+ND+PP+F     +  + E   +G+ I ++   D
Sbjct: 3379 SLTVQAADEGDPPLSSAVQVTVTVSDVNDNPPMFSKINHSLIVQEGEAVGSGILQLLVTD 3438

Query: 714  PDEGPNAV-VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS- 771
             D   N     + I  G++  SF +      D+  L+++        + ++ L I+    
Sbjct: 3439 RDTPQNGPPFSFHIVSGNEDRSFHI------DQGGLLSVSSQLRRRGKPQHLLKIQVTDS 3492

Query: 772  --PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQY 829
              PPL +   V+I +T+ +   P +   +I               ++ A D D  D L Y
Sbjct: 3493 GHPPLSSICVVKINITEQSRYPPTVNPLEIFITTAGGPILKSVISKLHATDQDPQDVLSY 3552

Query: 830  RILS-GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLIT 888
            +++S G +  L  ++   G + +   L+   P L  + VSVTDG   I A +++ V   T
Sbjct: 3553 KLVSEGQDKGLFSVDTVDGKIVVEKNLD---PGLYHLNVSVTDGKFSIWAGVKVHVWAAT 3609

Query: 889  EEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQ 937
            ++ L    T++L  ++AE+F+S         LA  +  P++ ++I S+Q
Sbjct: 3610 QQNLDQGFTLQLAGISAEEFVSDHWRGLQRSLAQELNIPRQELHIASLQ 3658



 Score =  317 bits (778), Expect = 3e-84
 Identities = 264/893 (29%), Positives = 405/893 (45%), Gaps = 61/893 (6%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I+V D ND++PVF+   Y A V EG   GT+VL + A D+D  KNAE  Y  +L+  ++
Sbjct: 2249 EIDVEDINDNAPVFQNLSYVADVFEGLPIGTSVLQVSAVDRDADKNAEATY--QLIDKES 2306

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                                F ID  SG L+T   LD E   ++T+ VKATD+  P    
Sbjct: 2307 ------------------HFFEIDPLSGVLVTTQVLDYESTQQFTLKVKATDKGVPP--- 2345

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            LS  A I VN+ID NDN P FSE +Y  S+DE    T   ++ K++A+D D  +   ++Y
Sbjct: 2346 LSGEAHIIVNVIDVNDNPPDFSEPSYRASLDE--MATCGNIVIKVQASDPD--SKDDLQY 2401

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             I+ GN    F+I+  SG +S            Y L +   DG       T  + I++ +
Sbjct: 2402 KILSGNEGRYFAINESSGLISFSNVCKRNLDPFYNLTVAVSDGVF---QKTAPVNIDMTN 2458

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
             N  +P F  ++++  ++EN  +G  ++R+ A D D+G    + YT+ +K      D   
Sbjct: 2459 GNKYSPYFTQNIYEADLAENAEVGTRVIRLAAIDPDDGPYGSVDYTIINK----LADEKF 2514

Query: 310  TIDPRSGWVYTSGQLDRE--TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
             I+   G + TS  LDRE  +Q    + + A DGG   R    T              F 
Sbjct: 2515 AIN-EDGQIVTSQPLDRENPSQRVIAIKIMAKDGGG--RVGFCTVKIILTDENDNVPQFK 2571

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITV 425
              +Y++ +      G+PV+ + A DADE     + Y +   +      I      G+++V
Sbjct: 2572 ASEYDISIQSTVNKGSPVIQIMAYDADEGKNADVTYTVEEADEVTEDIIEVNPFTGVVSV 2631

Query: 426  AQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
             + L   + + +   V A D G    + +  VQ+ +       P F    Y+ S  ED P
Sbjct: 2632 KESLVGLENKIFNFKVKARDGGFPFYNSSVPVQVKVVPPEIILPRFTEPLYSFSASEDLP 2691

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
            IG  +  V A D+D+     + YSL +   N   ++ +  F I+   G +     +D E 
Sbjct: 2692 IGYEIGTVKA-DADM----PLIYSLVN--GNTLDSNKELSFAIDKDGGTVVLQNNIDHEK 2744

Query: 544  MSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
               Y + V A+      +++    V I V DVNDN+P+F+   Y A + E+   GT+V Q
Sbjct: 2745 TKMYKIDVIAQGNHNGTNVASLVSVHIEVQDVNDNKPMFEADTYKAFLAENLPSGTTVIQ 2804

Query: 603  VGATDADVGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKALDRESVATHDLKAVAID 661
            V A DAD  +NG + Y L+P+  + G  F ID  +G I T K  D E+   H    VA D
Sbjct: 2805 VTANDADANINGEVSYTLEPESDDIGDMFAIDSQTGWITTLKEADSETKQLHRFFVVATD 2864

Query: 662  -GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-EGPN 719
             G    QS++V+V + + D ND+PP F  +     I ENS  G  I  +   D D    N
Sbjct: 2865 HGDALKQSASVLVEVTLTDENDNPPQFTEELYQGSILENSRPGENIVTLTTADKDVSAEN 2924

Query: 720  AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR 779
              +   I  GD    FS+ T  G ++  +++   LD E  + KY L I A          
Sbjct: 2925 RQIVCYITDGDPLGQFSV-TAVG-EEWTVISKSPLDRED-KDKYTLKIIATDGRFQTSAN 2981

Query: 780  VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRI-LSGNNAN 838
            VE+ V D+NDN+P  +  Q      ++        ++ A D D+    Q    L G NA+
Sbjct: 2982 VEVHVLDLNDNSPFCEQLQYTEAVMENSSSGKVILKISASDPDIGTNGQVSFTLHGPNAD 3041

Query: 839  LILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEM 891
               L+  TG +     L+    K   + V  TDG        Q  V L+ ++M
Sbjct: 3042 KFHLDPKTGELFTLAVLDREREKEYDLVVKATDGGGR---SCQADVTLMVQDM 3091



 Score =  294 bits (722), Expect = 2e-77
 Identities = 248/810 (30%), Positives = 374/810 (46%), Gaps = 64/810 (7%)

Query: 10   QINVLDCNDH--SPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
            +I VLD N++   P+F    + A+V E A  GT+VLTL A D D+G++  V Y I     
Sbjct: 1009 EIEVLDVNENLNRPLFGEMVHTAAVMEDAKIGTSVLTLTAVDNDLGRDGVVRYYIH---- 1064

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
                  D              VF +D  +G + T   LDRE V  Y + V A D  +   
Sbjct: 1065 ------DGSGLG---------VFTVDEETGVIQTAGLLDREVVPHYWLTVYAKDLGTIP- 1108

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
              L S   +++ + D NDN P+ S+  Y  SV E++   D  V+ K+ ATD D  +   +
Sbjct: 1109 --LVSWTEVYIEVWDINDNPPELSQPVYFGSVQENLP-KDKSVL-KVSATDMDKSSEGKL 1164

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
             + I+    ++ F+IDS +G +S + +LD EQ   + + +   D G P  S+T  ++I +
Sbjct: 1165 AFQILDSQ-RIYFTIDSKTGVISTLSSLDREQKAEHIIEVMVSDKGEPPLSSTATVVIEV 1223

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIG--YSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
             D NDN+P+F   LFQ  + E         I R+ A D D G N  +TY++ D +  G  
Sbjct: 1224 LDENDNSPQFSHKLFQIKLPERQSTAEPQDIYRMVARDDDVGPNGMITYSLEDNN-EGRF 1282

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLL-VTATDGGDPPRSATATXXXXXXXX---XX 361
            D    I P +G V   GQ  R     Y +L + ATD G+PPR + +              
Sbjct: 1283 D----IHPDTGVVTARGQFVR---GNYSILTIQATDQGNPPRMSKSRLHVEWLPQPEPSS 1335

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421
                F    +   + E +P  T +V +  T+  + N L ++I GG+    F I  +   G
Sbjct: 1336 DVLAFDEPPFNYVVMETDPV-TDMVGIIRTEIPK-NLLLFDIIGGDEEQDFYI--EKNTG 1391

Query: 422  LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
             I  A+ L+  ++  Y LTV  TD G ++ T    I + D N + P+F  + Y   V ED
Sbjct: 1392 SIVKARRLNAGKKSHYNLTVRVTD-GFQTITTQAYIQVVDINEHRPMFLKSLYEVRVPED 1450

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
                  +L +SA D+D   ++ + YS+ S ++ E++ +    F ++ ++G +   + LD 
Sbjct: 1451 TSPWKEILHISAHDADA--SSGLFYSIHSSLNPESLKY----FHLDQRSGVLVLKEELDY 1504

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
            ET+S + L V  RD  +P   +   V + V D ND+ P F    Y   I   AL GT V 
Sbjct: 1505 ETISTHTLIVMVRDDKIPIKKNFAKVVVHVEDCNDHIPSFLDTHYEGIISNLALTGTEVL 1564

Query: 602  QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
            +V A D D G N  I Y        +G+F ID  +G IR + ALDR     + L   A D
Sbjct: 1565 RVKALDKDTGSNADIVYSFHSGGNVDGAFKIDQGTGSIRVSDALDRLPQEHYHLTVKATD 1624

Query: 662  GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
             G P +S+   V I I+    +PP F S      ISE  P G+ +  + A  P       
Sbjct: 1625 QGFPQRSALCPVTITIKLSEFTPPRFSSKEYITEISEAMPPGSPVLSVSARCPSS----- 1679

Query: 722  VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP-LWNDVRV 780
            V Y I  GD + +F +    G     L     LD+E     Y L I A +   + +D  V
Sbjct: 1680 VLYRINEGDPNGTFHININSGL----LSVKNALDFEQ-HSSYHLQISATNTAGISSDAVV 1734

Query: 781  EILVTDVNDNAPVMKDFQIIFNNYKDCFPV 810
             + V D NDNAPV     + +    +  PV
Sbjct: 1735 FVYVIDANDNAPVFHQ-DVYYGQISESAPV 1763



 Score =  291 bits (714), Expect = 2e-76
 Identities = 267/939 (28%), Positives = 423/939 (45%), Gaps = 76/939 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I + + ND+ PVFE     AS+    + G  +  + A D D  +  ++ Y IE    D L
Sbjct: 546  ITMTNVNDNVPVFERVACNASIPRDFAVGEIIAEISALDLD--ELQQIVYRIESGNDDGL 603

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQAS----- 124
               D           +   ++    S   L   + D   +A   TV V  TD        
Sbjct: 604  FSIDPVSGIIKLAKAIPSNYKDTENSLYTLKITATDGTYIADPNTVTVSITDNGEGAITH 663

Query: 125  --------PVSDRLSSTATIHVNIIDD---------NDNYPQFSEKTY-TVSVDEDISVT 166
                     ++++L  +    +NI ++         N + P+F   T  ++ + ED ++ 
Sbjct: 664  CEETGITRQLTEKLIESFRPSLNIKEEESISDVHIINQHSPKFVISTPGSIDIREDFAL- 722

Query: 167  DNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLV 226
             N  + +  ATD D G N  + Y+I  GN    F+ID  +GD+ ++  LD EQ   Y L 
Sbjct: 723  -NRSVLQFNATDNDSGFNGKLVYSISSGNEDGCFTIDVNAGDLKVICALDREQKEFYILN 781

Query: 227  IRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE 286
            I   D G P  S    L +NI D NDN P F  S +  ++ EN  +  SI +V A D D 
Sbjct: 782  ITVYDLGYPQTSTWKLLAVNILDANDNPPLFSQSRYVVTIPENTEVDKSIFKVNAVDFDL 841

Query: 287  GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG--DP 344
              N    Y++    +T   DL   I+  +G V   G LDRET  +Y L + A D    DP
Sbjct: 842  DNNGAFKYSL----FT-FTDL-FQIEEDTGVVKVIGPLDRETFRRYDLTIEARDQAKPDP 895

Query: 345  PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYE 402
               +                 F+P  Y++++ ED PPGT ++ + + D D ++   + Y 
Sbjct: 896  QLFSFTDVVVVLEDINDNPPKFVPTVYKIKVPEDVPPGTVLLWVESFDLDLESGGVISYN 955

Query: 403  ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINI 459
            +    + G F + +  G   +T+ + LDF++ + Y LTV A D G     S +  ++I +
Sbjct: 956  LKNSES-GTFFLDTSTGS--LTLERELDFEKRQFYNLTVRAVDHGKPRSLSSSCFIEIEV 1012

Query: 460  TDANN--YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517
             D N     P+F    +TA+V EDA IGT+VL ++A D+D+G +  + Y +  + S   V
Sbjct: 1013 LDVNENLNRPLFGEMVHTAAVMEDAKIGTSVLTLTAVDNDLGRDGVVRYYI-HDGSGLGV 1071

Query: 518  AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577
                  F ++ +TG I T  LLDRE +  Y LTV A+D G   L   T+V I V D+NDN
Sbjct: 1072 ------FTVDEETGVIQTAGLLDREVVPHYWLTVYAKDLGTIPLVSWTEVYIEVWDINDN 1125

Query: 578  EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637
             P   Q +Y  ++ E+     SV +V ATD D    G++ +++   D +   F ID  +G
Sbjct: 1126 PPELSQPVYFGSVQENLPKDKSVLKVSATDMDKSSEGKLAFQI--LDSQRIYFTIDSKTG 1183

Query: 638  VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697
            VI T  +LDRE  A H ++ +  D G PP SST  V I++ D ND+ P F        + 
Sbjct: 1184 VISTLSSLDREQKAEHIIEVMVSDKGEPPLSSTATVVIEVLDENDNSPQFSHKLFQIKLP 1243

Query: 698  ENSPIG--TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755
            E         I  + A D D GPN ++ YS++  ++   F +    G        +V   
Sbjct: 1244 ERQSTAEPQDIYRMVARDDDVGPNGMITYSLEDNNEGR-FDIHPDTG--------VVTAR 1294

Query: 756  YESPRKKYE-LVIRA---ASPPLWNDVRVEI-LVTDVNDNAPVMKDFQIIFNN-YKDCFP 809
             +  R  Y  L I+A    +PP  +  R+ +  +     ++ V+   +  FN    +  P
Sbjct: 1295 GQFVRGNYSILTIQATDQGNPPRMSKSRLHVEWLPQPEPSSDVLAFDEPPFNYVVMETDP 1354

Query: 810  VGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSV 869
            V     +   +    + L + I+ G+      + + TGS+  + +LN        + V V
Sbjct: 1355 VTDMVGIIRTEIP-KNLLLFDIIGGDEEQDFYIEKNTGSIVKARRLNAGKKSHYNLTVRV 1413

Query: 870  TDGVNEIKAMMQLSVRLITEE--MLLNSI-TVRLNDMTA 905
            TDG   I     + V  I E   M L S+  VR+ + T+
Sbjct: 1414 TDGFQTITTQAYIQVVDINEHRPMFLKSLYEVRVPEDTS 1452



 Score =  283 bits (694), Expect = 5e-74
 Identities = 247/880 (28%), Positives = 400/880 (45%), Gaps = 70/880 (7%)

Query: 8    HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
            H  +NV+D ND+ P F    Y AS+ E A+ G  V+ ++A+D D     +++Y I     
Sbjct: 2351 HIIVNVIDVNDNPPDFSEPSYRASLDEMATCGNIVIKVQASDPD--SKDDLQYKI----- 2403

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
              L+  +               F I+  SG +       R     Y + V  +D      
Sbjct: 2404 --LSGNEGR------------YFAINESSGLISFSNVCKRNLDPFYNLTVAVSDGV---- 2445

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
                 TA +++++ + N   P F++  Y   + E+  V     + ++ A D D G   ++
Sbjct: 2446 --FQKTAPVNIDMTNGNKYSPYFTQNIYEADLAENAEVGTR--VIRLAAIDPDDGPYGSV 2501

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYE--QVRSYRLVIRAQDGGSPSRSNTTQLLI 245
             Y II      +F+I+   G +   + LD E    R   + I A+DGG      T ++++
Sbjct: 2502 DYTIINKLADEKFAINE-DGQIVTSQPLDRENPSQRVIAIKIMAKDGGGRVGFCTVKIIL 2560

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
               D NDN P+F  S +  S+   V  G  ++++ AYDADEG NA++TYT+ + D     
Sbjct: 2561 T--DENDNVPQFKASEYDISIQSTVNKGSPVIQIMAYDADEGKNADVTYTVEEADEV-TE 2617

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
            D+ I ++P +G V     L       +   V A DGG P  +++                
Sbjct: 2618 DI-IEVNPFTGVVSVKESLVGLENKIFNFKVKARDGGFPFYNSSVPVQVKVVPPEIILPR 2676

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT---RGRFSITSQNGRGL 422
            F    Y    +ED P G  + T+    AD D  L Y +  GNT       S       G 
Sbjct: 2677 FTEPLYSFSASEDLPIGYEIGTV---KADADMPLIYSLVNGNTLDSNKELSFAIDKDGGT 2733

Query: 423  ITVAQPLDFKQERRYVLTVSATDSGGRSDTA---MVQINITDANNYAPVFENAPYTASVF 479
            + +   +D ++ + Y + V A  +   ++ A    V I + D N+  P+FE   Y A + 
Sbjct: 2734 VVLQNNIDHEKTKMYKIDVIAQGNHNGTNVASLVSVHIEVQDVNDNKPMFEADTYKAFLA 2793

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
            E+ P GTTV+ V+A D+D  IN +++Y+L  E S++        F I+ QTG ITT K  
Sbjct: 2794 ENLPSGTTVIQVTANDADANINGEVSYTLEPE-SDDI----GDMFAIDSQTGWITTLKEA 2848

Query: 540  DRETMSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            D ET   +   V A D G     S +  VE+++ D NDN P F ++LY  +I+E++  G 
Sbjct: 2849 DSETKQLHRFFVVATDHGDALKQSASVLVEVTLTDENDNPPQFTEELYQGSILENSRPGE 2908

Query: 599  SVSQVGATDADVGLNGR--IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
            ++  +   D DV    R  + Y  D     + S         + +   LDRE    + LK
Sbjct: 2909 NIVTLTTADKDVSAENRQIVCYITDGDPLGQFSVTAVGEEWTVISKSPLDREDKDKYTLK 2968

Query: 657  AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
             +A DG     S+ V VH+   D+ND+ P  E    T  + ENS  G  I +I A DPD 
Sbjct: 2969 IIATDGRF-QTSANVEVHVL--DLNDNSPFCEQLQYTEAVMENSSSGKVILKISASDPDI 3025

Query: 717  GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN 776
            G N  V +++  G +++ F L+ + G    EL T+  LD E   K+Y+LV++A      +
Sbjct: 3026 GTNGQVSFTLH-GPNADKFHLDPKTG----ELFTLAVLDRER-EKEYDLVVKATDGGGRS 3079

Query: 777  -DVRVEILVTDVNDNAPVM--KDFQI-IFNNYKDCFPVGP-FGRVPAYDADVTDKLQYRI 831
                V ++V D+NDN P      +++ +F+N     P+   + + P  D  +  +++Y  
Sbjct: 3080 CQADVTLMVQDMNDNPPQFSTSHYEVTVFDNTTIRTPIAVIYAKDP--DTGINSEVRYS- 3136

Query: 832  LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            L G ++    L+E +G + L   L         M+V  TD
Sbjct: 3137 LQGADSGFFSLDEISGVLRLERSLADETKSTYEMKVKATD 3176



 Score =  278 bits (682), Expect = 1e-72
 Identities = 252/880 (28%), Positives = 394/880 (44%), Gaps = 74/880 (8%)

Query: 17   NDHSPVFEMQQYEA-SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDA 75
            N HSP F +    +  +RE  +   +VL   ATD D G N ++ Y+I     D       
Sbjct: 700  NQHSPKFVISTPGSIDIREDFALNRSVLQFNATDNDSGFNGKLVYSISSGNED------- 752

Query: 76   XXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTAT 135
                          F ID  +G L    +LDRE+   Y + +   D   P   + S+   
Sbjct: 753  ------------GCFTIDVNAGDLKVICALDREQKEFYILNITVYDLGYP---QTSTWKL 797

Query: 136  IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195
            + VNI+D NDN P FS+  Y V++ E+  V  +  I K+ A D D+  N A +Y++    
Sbjct: 798  LAVNILDANDNPPLFSQSRYVVTIPENTEVDKS--IFKVNAVDFDLDNNGAFKYSLF-TF 854

Query: 196  TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS--NTTQLLINIRDVNDN 253
            T + F I+  +G V ++  LD E  R Y L I A+D   P     + T +++ + D+NDN
Sbjct: 855  TDL-FQIEEDTGVVKVIGPLDRETFRRYDLTIEARDQAKPDPQLFSFTDVVVVLEDINDN 913

Query: 254  APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313
             P+F  ++++  V E+VP G  ++ V+++D D      ++Y + + + +G       +D 
Sbjct: 914  PPKFVPTVYKIKVPEDVPPGTVLLWVESFDLDLESGGVISYNLKNSE-SGT----FFLDT 968

Query: 314  RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP--GQ- 370
             +G +    +LD E +  Y L V A D G  PRS +++                P  G+ 
Sbjct: 969  STGSLTLERELDFEKRQFYNLTVRAVDHG-KPRSLSSSCFIEIEVLDVNENLNRPLFGEM 1027

Query: 371  -YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
             +   + ED   GT V+TLTA D D   D  + Y I  G+  G F++  +   G+I  A 
Sbjct: 1028 VHTAAVMEDAKIGTSVLTLTAVDNDLGRDGVVRYYIHDGSGLGVFTVDEET--GVIQTAG 1085

Query: 428  PLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
             LD +    Y LTV A D G         V I + D N+  P      Y  SV E+ P  
Sbjct: 1086 LLDREVVPHYWLTVYAKDLGTIPLVSWTEVYIEVWDINDNPPELSQPVYFGSVQENLPKD 1145

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
             +VL VSATD D     ++ + +   + ++ +      F I+ +TG I+T   LDRE  +
Sbjct: 1146 KSVLKVSATDMDKSSEGKLAFQI---LDSQRI-----YFTIDSKTGVISTLSSLDREQKA 1197

Query: 546  GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME--DALVGTSVSQV 603
             +++ V   D G P LS T  V I V+D NDN P F  +L+   + E         + ++
Sbjct: 1198 EHIIEVMVSDKGEPPLSSTATVVIEVLDENDNSPQFSHKLFQIKLPERQSTAEPQDIYRM 1257

Query: 604  GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
             A D DVG NG I Y L+  D  EG F I P +GV+       R + +   L   A D G
Sbjct: 1258 VARDDDVGPNGMITYSLE--DNNEGRFDIHPDTGVVTARGQFVRGNYSI--LTIQATDQG 1313

Query: 664  TPPQSSTVIVHIK-IEDINDSPPV--FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
             PP+ S   +H++ +     S  V  F+     + + E  P+   +G IR     E P  
Sbjct: 1314 NPPRMSKSRLHVEWLPQPEPSSDVLAFDEPPFNYVVMETDPVTDMVGIIRT----EIPKN 1369

Query: 721  VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRV 780
            ++ + I GGD+   F +E   GS    +V    L+    +  Y L +R          + 
Sbjct: 1370 LLLFDIIGGDEEQDFYIEKNTGS----IVKARRLN-AGKKSHYNLTVRVTDGFQTITTQA 1424

Query: 781  EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLI 840
             I V D+N++ P+           +D  P      + A+DAD +  L Y I S  N   +
Sbjct: 1425 YIQVVDINEHRPMFLKSLYEVRVPEDTSPWKEILHISAHDADASSGLFYSIHSSLNPESL 1484

Query: 841  L---LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIK 877
                L++ +G + L  +L+       T+ V V D    IK
Sbjct: 1485 KYFHLDQRSGVLVLKEELDYETISTHTLIVMVRDDKIPIK 1524



 Score =  264 bits (647), Expect = 2e-68
 Identities = 223/787 (28%), Positives = 368/787 (46%), Gaps = 47/787 (5%)

Query: 133  TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192
            T  + +NI +   +  +F ++ +  +V E+   T   ++  ++AT   +  N  +++ ++
Sbjct: 1941 TTVVKLNITNATKSSLKFEDRAHVATVLENS--TSVKILVVLRATGTYL--NEPLQFTVL 1996

Query: 193  GGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251
              N   +F++   SG +       D E+   Y + +  +D  SP R + T + + I DVN
Sbjct: 1997 --NPHGKFAVIPSSGVLHTTGVPFDREEQDVYDVAVEVRDFRSPPRVDVTHVKVYIDDVN 2054

Query: 252  DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311
            DN P          +S+    G  + +V A D D G N  + +++ D      +DL +  
Sbjct: 2055 DNVPEILNLPKTLLISDETEPGDVLFQVLATDNDFGENGSIIFSLEDDFGLFRIDLYL-- 2112

Query: 312  DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371
                G V     LD E+  KY L V  +D G P  SA  T              F    Y
Sbjct: 2113 ----GDVSLQRPLDFESMNKYVLTVLVSDDGQPSLSAIGTIYIQVQNRSHPI--FQSMYY 2166

Query: 372  EVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431
             ++L E+  P T ++ + A +  E  RL Y +   N    F+I  + G  +++V   LDF
Sbjct: 2167 PLKLPENITPFTTILHVQARNP-EGYRLIYNLEEDNASRLFNIDFKTG--VLSVTDFLDF 2223

Query: 432  KQERRYVLTVSATDS-GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
            + E +++LTV ATDS  G    A V+I++ D N+ APVF+N  Y A VFE  PIGT+VL 
Sbjct: 2224 ESETKHILTVRATDSVSGTFAEAKVEIDVEDINDNAPVFQNLSYVADVFEGLPIGTSVLQ 2283

Query: 491  VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550
            VSA D D   NA+ TY L   I  E+  H    F I+P +G + T ++LD E+   + L 
Sbjct: 2284 VSAVDRDADKNAEATYQL---IDKES--HF---FEIDPLSGVLVTTQVLDYESTQQFTLK 2335

Query: 551  VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610
            V A D GVP LS    + ++V+DVNDN P F +  Y A++ E A  G  V +V A+D D 
Sbjct: 2336 VKATDKGVPPLSGEAHIIVNVIDVNDNPPDFSEPSYRASLDEMATCGNIVIKVQASDPD- 2394

Query: 611  GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST 670
                 + Y++     E   F I+ +SG+I  +    R     ++L     DG       T
Sbjct: 2395 -SKDDLQYKI-LSGNEGRYFAINESSGLISFSNVCKRNLDPFYNLTVAVSDG---VFQKT 2449

Query: 671  VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD 730
              V+I + + N   P F  +     ++EN+ +GT +  + A DPD+GP   V Y+I    
Sbjct: 2450 APVNIDMTNGNKYSPYFTQNIYEADLAENAEVGTRVIRLAAIDPDDGPYGSVDYTIINKL 2509

Query: 731  DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDV---RVEILVTDV 787
                F++     ++  ++VT   LD E+P ++  + I+  +      V    V+I++TD 
Sbjct: 2510 ADEKFAI-----NEDGQIVTSQPLDRENPSQRV-IAIKIMAKDGGGRVGFCTVKIILTDE 2563

Query: 788  NDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNA--NLILLN 843
            NDN P  K  +   +         P  ++ AYDAD      + Y +   +    ++I +N
Sbjct: 2564 NDNVPQFKASEYDISIQSTVNKGSPVIQIMAYDADEGKNADVTYTVEEADEVTEDIIEVN 2623

Query: 844  ETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEEMLLNSITVRLND 902
              TG +++   L     K+   +V   D G     + + + V+++  E++L   T  L  
Sbjct: 2624 PFTGVVSVKESLVGLENKIFNFKVKARDGGFPFYNSSVPVQVKVVPPEIILPRFTEPLYS 2683

Query: 903  MTAEQFL 909
             +A + L
Sbjct: 2684 FSASEDL 2690



 Score =  264 bits (646), Expect = 3e-68
 Identities = 228/869 (26%), Positives = 381/869 (43%), Gaps = 65/869 (7%)

Query: 15   DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
            D ND+ P F    Y+  V E    GT +L +++ D D+     + Y ++       N E 
Sbjct: 909  DINDNPPKFVPTVYKIKVPEDVPPGTVLLWVESFDLDLESGGVISYNLK-------NSES 961

Query: 75   AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134
                           F +D  +G+L     LD EK   Y + V+A D   P S  LSS+ 
Sbjct: 962  GT-------------FFLDTSTGSLTLERELDFEKRQFYNLTVRAVDHGKPRS--LSSSC 1006

Query: 135  TIHVNIIDDNDNY--PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192
             I + ++D N+N   P F E  +T +V ED  +  +  +  + A D D+G +  +RY I 
Sbjct: 1007 FIEIEVLDVNENLNRPLFGEMVHTAAVMEDAKIGTS--VLTLTAVDNDLGRDGVVRYYIH 1064

Query: 193  GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252
             G+    F++D  +G +     LD E V  Y L + A+D G+    + T++ I + D+ND
Sbjct: 1065 DGSGLGVFTVDEETGVIQTAGLLDREVVPHYWLTVYAKDLGTIPLVSWTEVYIEVWDIND 1124

Query: 253  NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312
            N P     ++  SV EN+P   S+++V A D D+    +L + + D        +  TID
Sbjct: 1125 NPPELSQPVYFGSVQENLPKDKSVLKVSATDMDKSSEGKLAFQILDSQ-----RIYFTID 1179

Query: 313  PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE 372
             ++G + T   LDRE +A++ + V  +D G+PP S+TAT              F    ++
Sbjct: 1180 SKTGVISTLSSLDREQKAEHIIEVMVSDKGEPPLSSTATVVIEVLDENDNSPQFSHKLFQ 1239

Query: 373  VELAEDEPPGTP--VVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
            ++L E +    P  +  + A D D   +  + Y +   N  GRF I    G     V   
Sbjct: 1240 IKLPERQSTAEPQDIYRMVARDDDVGPNGMITYSLE-DNNEGRFDIHPDTG----VVTAR 1294

Query: 429  LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
              F +    +LT+ ATD G     +  ++++     + P  E +      F++ P    V
Sbjct: 1295 GQFVRGNYSILTIQATDQGNPPRMSKSRLHV----EWLPQPEPSS-DVLAFDEPPFNYVV 1349

Query: 489  LVVSATDSDVG-INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
            +        VG I  +I  +L   + +      +Q F I   TG+I   + L+    S Y
Sbjct: 1350 METDPVTDMVGIIRTEIPKNLL--LFDIIGGDEEQDFYIEKNTGSIVKARRLNAGKKSHY 1407

Query: 548  LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
             LTV   DG     + TT   I VVD+N++ P+F + LY   + ED      +  + A D
Sbjct: 1408 NLTVRVTDG---FQTITTQAYIQVVDINEHRPMFLKSLYEVRVPEDTSPWKEILHISAHD 1464

Query: 608  ADV--GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
            AD   GL   IH  L+P+  +   F +D  SGV+   + LD E+++TH L  +  D   P
Sbjct: 1465 ADASSGLFYSIHSSLNPESLK--YFHLDQRSGVLVLKEELDYETISTHTLIVMVRDDKIP 1522

Query: 666  PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
             + +   V + +ED ND  P F        IS  +  GT +  ++A D D G NA + YS
Sbjct: 1523 IKKNFAKVVVHVEDCNDHIPSFLDTHYEGIISNLALTGTEVLRVKALDKDTGSNADIVYS 1582

Query: 726  I-KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP--PLWNDVRVEI 782
               GG+   +F ++   GS     + + D     P++ Y L ++A     P  + +    
Sbjct: 1583 FHSGGNVDGAFKIDQGTGS-----IRVSDALDRLPQEHYHLTVKATDQGFPQRSALCPVT 1637

Query: 783  LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILL 842
            +   +++  P     +       +  P  P   V +  A     + YRI  G+      +
Sbjct: 1638 ITIKLSEFTPPRFSSKEYITEISEAMP--PGSPVLSVSARCPSSVLYRINEGDPNGTFHI 1695

Query: 843  NETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            N  +G +++   L+        +++S T+
Sbjct: 1696 NINSGLLSVKNALDFEQHSSYHLQISATN 1724



 Score =  263 bits (645), Expect = 4e-68
 Identities = 211/718 (29%), Positives = 334/718 (46%), Gaps = 58/718 (8%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            F I+  +G+++    L+  K + Y + V+ TD    +      T   ++ ++D N++ P 
Sbjct: 1384 FYIEKNTGSIVKARRLNAGKKSHYNLTVRVTDGFQTI------TTQAYIQVVDINEHRPM 1437

Query: 150  FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI---IGGNTQMQFSIDSLS 206
            F +  Y V V ED S      I  I A DAD  A+S + Y+I   +   +   F +D  S
Sbjct: 1438 FLKSLYEVRVPEDTSPWKE--ILHISAHDAD--ASSGLFYSIHSSLNPESLKYFHLDQRS 1493

Query: 207  GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266
            G + L + LDYE + ++ L++  +D   P + N  ++++++ D ND+ P F  + ++  +
Sbjct: 1494 GVLVLKEELDYETISTHTLIVMVRDDKIPIKKNFAKVVVHVEDCNDHIPSFLDTHYEGII 1553

Query: 267  SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326
            S     G  ++RV+A D D G NA++ Y+       GNVD    ID  +G +  S  LDR
Sbjct: 1554 SNLALTGTEVLRVKALDKDTGSNADIVYSFHSG---GNVDGAFKIDQGTGSIRVSDALDR 1610

Query: 327  ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386
              Q  Y L V ATD G P RSA                 F   +Y  E++E  PPG+PV+
Sbjct: 1611 LPQEHYHLTVKATDQGFPQRSALCPVTITIKLSEFTPPRFSSKEYITEISEAMPPGSPVL 1670

Query: 387  TLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446
            +++A        + Y I  G+  G F I   +G  L++V   LDF+Q   Y L +SAT++
Sbjct: 1671 SVSARCPSS---VLYRINEGDPNGTFHININSG--LLSVKNALDFEQHSSYHLQISATNT 1725

Query: 447  GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT-------TVLVVSATDSDVG 499
             G S  A+V + + DAN+ APVF    Y   + E AP+ +       T LV+ A+D+D  
Sbjct: 1726 AGISSDAVVFVYVIDANDNAPVFHQDVYYGQISESAPVNSMVTGENNTPLVIKASDADKD 1785

Query: 500  INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
             NA + Y +      E  AH  + F I+P  G I+   L+D E    +  +V   D G P
Sbjct: 1786 TNALLVYQIL-----EPAAH--EVFKIDPSMGTISLKSLIDFEATPEFFFSVQVWDSGEP 1838

Query: 560  SLSDT--TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617
            SLS +    V I V+D ND  P F   +Y   +         V QV A DAD  +   I 
Sbjct: 1839 SLSASKPCKVIIRVLDFNDCPPKFVLPVYEIALTWPVFQDMKVIQVTAHDADSAVTYMI- 1897

Query: 618  YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
                 ++  + +F ID ++GVI  N + + +S   ++LK  A DG       T +V + I
Sbjct: 1898 ----LENSNKNAFKIDQSTGVISVNDSSELQS--HNELKITAFDG---LYKDTTVVKLNI 1948

Query: 678  EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL 737
             +   S   FE       + ENS     +  +RA       N  + +++   +    F++
Sbjct: 1949 TNATKSSLKFEDRAHVATVLENSTSVKILVVLRA--TGTYLNEPLQFTVL--NPHGKFAV 2004

Query: 738  ETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792
                G       T V  D E  +  Y++ +      SPP  +   V++ + DVNDN P
Sbjct: 2005 IPSSG---VLHTTGVPFDREE-QDVYDVAVEVRDFRSPPRVDVTHVKVYIDDVNDNVP 2058



 Score =  240 bits (587), Expect = 5e-61
 Identities = 242/901 (26%), Positives = 404/901 (44%), Gaps = 80/901 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND+ P      Y  SV+E      +VL + ATD D  K++E +   +++ +  +
Sbjct: 1117 IEVWDINDNPPELSQPVYFGSVQENLPKDKSVLKVSATDMD--KSSEGKLAFQILDSQRI 1174

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F ID ++G + T +SLDRE+ A + + V  +D+  P    L
Sbjct: 1175 ------------------YFTIDSKTGVISTLSSLDREQKAEHIIEVMVSDKGEPP---L 1213

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            SSTAT+ + ++D+NDN PQFS K + + + E  S  +   I ++ A D DVG N  I Y+
Sbjct: 1214 SSTATVVIEVLDENDNSPQFSHKLFQIKLPERQSTAEPQDIYRMVARDDDVGPNGMITYS 1273

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVR-SYR-LVIRAQDGGSPSRSNTTQLLINIR 248
            +   N + +F I   +G    V T   + VR +Y  L I+A D G+P R + ++L  ++ 
Sbjct: 1274 L-EDNNEGRFDIHPDTG----VVTARGQFVRGNYSILTIQATDQGNPPRMSKSRL--HVE 1326

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV-NAELTYTMTDKDYTG-NVD 306
             +    P      F E      P  Y ++         G+   E+   +   D  G + +
Sbjct: 1327 WLPQPEPSSDVLAFDEP-----PFNYVVMETDPVTDMVGIIRTEIPKNLLLFDIIGGDEE 1381

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
                I+  +G +  + +L+   ++ Y L V  TDG    ++ T                F
Sbjct: 1382 QDFYIEKNTGSIVKARRLNAGKKSHYNLTVRVTDGF---QTITTQAYIQVVDINEHRPMF 1438

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG-NTRGRFSITSQNGRGLITV 425
            +   YEV + ED  P   ++ ++A DAD  + L Y I    N             G++ +
Sbjct: 1439 LKSLYEVRVPEDTSPWKEILHISAHDADASSGLFYSIHSSLNPESLKYFHLDQRSGVLVL 1498

Query: 426  AQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
             + LD++    + L V   D     + + A V +++ D N++ P F +  Y   +   A 
Sbjct: 1499 KEELDYETISTHTLIVMVRDDKIPIKKNFAKVVVHVEDCNDHIPSFLDTHYEGIISNLAL 1558

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
             GT VL V A D D G NA I YS  S        + D  F I+  TG+I  +  LDR  
Sbjct: 1559 TGTEVLRVKALDKDTGSNADIVYSFHSG------GNVDGAFKIDQGTGSIRVSDALDRLP 1612

Query: 544  MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
               Y LTV A D G P  S    V I++       P F  + Y   I E    G+ V  V
Sbjct: 1613 QEHYHLTVKATDQGFPQRSALCPVTITIKLSEFTPPRFSSKEYITEISEAMPPGSPVLSV 1672

Query: 604  GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
             A      L  RI+ E DP     G+F I+  SG++    ALD E  +++ L+  A +  
Sbjct: 1673 SARCPSSVLY-RIN-EGDPN----GTFHININSGLLSVKNALDFEQHSSYHLQISATN-- 1724

Query: 664  TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI-GE------IRAHDPDE 716
            T   SS  +V + + D ND+ PVF  D     ISE++P+ + + GE      I+A D D+
Sbjct: 1725 TAGISSDAVVFVYVIDANDNAPVFHQDVYYGQISESAPVNSMVTGENNTPLVIKASDADK 1784

Query: 717  GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN 776
              NA++ Y I        F ++   G+    L +++D +  +P   + + +  +  P  +
Sbjct: 1785 DTNALLVYQILEPAAHEVFKIDPSMGT--ISLKSLIDFE-ATPEFFFSVQVWDSGEPSLS 1841

Query: 777  ---DVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRI 831
                 +V I V D ND  P  V+  ++I        F      +V A+DAD    + Y I
Sbjct: 1842 ASKPCKVIIRVLDFNDCPPKFVLPVYEIALT--WPVFQDMKVIQVTAHDAD--SAVTYMI 1897

Query: 832  LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEM 891
            L  +N N   ++++TG ++++   ++ +     ++++  DG+ +   +++L++   T+  
Sbjct: 1898 LENSNKNAFKIDQSTGVISVND--SSELQSHNELKITAFDGLYKDTTVVKLNITNATKSS 1955

Query: 892  L 892
            L
Sbjct: 1956 L 1956



 Score =  228 bits (557), Expect = 2e-57
 Identities = 240/903 (26%), Positives = 403/903 (44%), Gaps = 81/903 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +N+LD ND+ P+F   +Y  ++ E      ++  + A D D+  N   +Y++   T    
Sbjct: 800  VNILDANDNPPLFSQSRYVVTIPENTEVDKSIFKVNAVDFDLDNNGAFKYSLFTFT---- 855

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                             D+F+I+  +G +     LDRE   RY + ++A DQA P   +L
Sbjct: 856  -----------------DLFQIEEDTGVVKVIGPLDRETFRRYDLTIEARDQAKP-DPQL 897

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             S   + V + D NDN P+F    Y + V ED  V    V+  +++ D D+ +   I Y 
Sbjct: 898  FSFTDVVVVLEDINDNPPKFVPTVYKIKVPED--VPPGTVLLWVESFDLDLESGGVISYN 955

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP-SRSNTTQLLINIRD 249
            +    +   F +D+ +G ++L + LD+E+ + Y L +RA D G P S S++  + I + D
Sbjct: 956  LKNSESG-TFFLDTSTGSLTLERELDFEKRQFYNLTVRAVDHGKPRSLSSSCFIEIEVLD 1014

Query: 250  VND--NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            VN+  N P F   +   +V E+  IG S++ + A D D G +  + Y + D    G    
Sbjct: 1015 VNENLNRPLFGEMVHTAAVMEDAKIGTSVLTLTAVDNDLGRDGVVRYYIHDGSGLG---- 1070

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
              T+D  +G + T+G LDRE    Y L V A D G  P  +                   
Sbjct: 1071 VFTVDEETGVIQTAGLLDREVVPHYWLTVYAKDLGTIPLVSWTEVYIEVWDINDNPPELS 1130

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITV 425
               Y   + E+ P    V+ ++ATD D+  + +L ++I   + R  F+I S+   G+I+ 
Sbjct: 1131 QPVYFGSVQENLPKDKSVLKVSATDMDKSSEGKLAFQIL-DSQRIYFTIDSKT--GVIST 1187

Query: 426  AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
               LD +Q+  +++ V  +D G    S TA V I + D N+ +P F +  +   + E   
Sbjct: 1188 LSSLDREQKAEHIIEVMVSDKGEPPLSSTATVVIEVLDENDNSPQFSHKLFQIKLPERQS 1247

Query: 484  IG--TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
                  +  + A D DVG N  ITYSL  E +NE       +F I+P TG +T      R
Sbjct: 1248 TAEPQDIYRMVARDDDVGPNGMITYSL--EDNNEG------RFDIHPDTGVVTARGQFVR 1299

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVV---DVNDNEPVFKQQLYTANIMEDALVGT 598
               S  +LT+ A D G P     + + +  +   + + +   F +  +   +ME   V  
Sbjct: 1300 GNYS--ILTIQATDQGNPPRMSKSRLHVEWLPQPEPSSDVLAFDEPPFNYVVMETDPV-- 1355

Query: 599  SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
                VG    ++  N  + +++   D EE  F I+  +G I   + L+    + ++L   
Sbjct: 1356 -TDMVGIIRTEIPKN-LLLFDIIGGD-EEQDFYIEKNTGSIVKARRLNAGKKSHYNLTVR 1412

Query: 659  AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
              DG    Q+ T   +I++ DIN+  P+F        + E++     I  I AHD D   
Sbjct: 1413 VTDGF---QTITTQAYIQVVDINEHRPMFLKSLYEVRVPEDTSPWKEILHISAHDAD--A 1467

Query: 719  NAVVHYSIKGGDDSNS---FSLETRQGSDKAELVTMVDLDYESPRKKYELV-IRAASPPL 774
            ++ + YSI    +  S   F L+ R G     LV   +LDYE+      +V +R    P+
Sbjct: 1468 SSGLFYSIHSSLNPESLKYFHLDQRSG----VLVLKEELDYETISTHTLIVMVRDDKIPI 1523

Query: 775  -WNDVRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQY 829
              N  +V + V D ND+ P   D  ++ I +N           RV A D D      + Y
Sbjct: 1524 KKNFAKVVVHVEDCNDHIPSFLDTHYEGIISNL--ALTGTEVLRVKALDKDTGSNADIVY 1581

Query: 830  RILSGNNAN-LILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLI 887
               SG N +    +++ TGS+ +S  L+    +   + V  TD G  +  A+  +++ + 
Sbjct: 1582 SFHSGGNVDGAFKIDQGTGSIRVSDALDRLPQEHYHLTVKATDQGFPQRSALCPVTITIK 1641

Query: 888  TEE 890
              E
Sbjct: 1642 LSE 1644



 Score =  202 bits (492), Expect = 1e-49
 Identities = 225/884 (25%), Positives = 383/884 (43%), Gaps = 89/884 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V+D N+H P+F    YE  V E  S    +L + A D D   ++ + Y+I      +L
Sbjct: 1426 IQVVDINEHRPMFLKSLYEVRVPEDTSPWKEILHISAHDAD--ASSGLFYSIH----SSL 1479

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            NPE                F +D RSG L+ +  LD E ++ +T++V   D   P+    
Sbjct: 1480 NPESL------------KYFHLDQRSGVLVLKEELDYETISTHTLIVMVRDDKIPIK--- 1524

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             + A + V++ D ND+ P F + T+   +  ++++T   V+ ++KA D D G+N+ I Y+
Sbjct: 1525 KNFAKVVVHVEDCNDHIPSFLD-THYEGIISNLALTGTEVL-RVKALDKDTGSNADIVYS 1582

Query: 191  I-IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
               GGN    F ID  +G + +   LD      Y L ++A D G P RS    + I I+ 
Sbjct: 1583 FHSGGNVDGAFKIDQGTGSIRVSDALDRLPQEHYHLTVKATDQGFPQRSALCPVTITIKL 1642

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
                 PRF +  +   +SE +P G  ++ V A        + + Y + + D  G   + I
Sbjct: 1643 SEFTPPRFSSKEYITEISEAMPPGSPVLSVSA-----RCPSSVLYRINEGDPNGTFHINI 1697

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
                 SG +     LD E  + Y L ++AT+      S+ A               F   
Sbjct: 1698 ----NSGLLSVKNALDFEQHSSYHLQISATNTAG--ISSDAVVFVYVIDANDNAPVFHQD 1751

Query: 370  QYEVELAEDEPPGTPV-------VTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGR 420
             Y  +++E  P  + V       + + A+DAD+D    L Y+I        F I      
Sbjct: 1752 VYYGQISESAPVNSMVTGENNTPLVIKASDADKDTNALLVYQILEPAAHEVFKI--DPSM 1809

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNYAPVFENAPYTA 476
            G I++   +DF+    +  +V   DSG      S    V I + D N+  P F    Y  
Sbjct: 1810 GTISLKSLIDFEATPEFFFSVQVWDSGEPSLSASKPCKVIIRVLDFNDCPPKFVLPVYEI 1869

Query: 477  SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
            ++         V+ V+A D+D    + +TY +  E SN+        F I+  TG I+ N
Sbjct: 1870 ALTWPVFQDMKVIQVTAHDAD----SAVTYMI-LENSNK------NAFKIDQSTGVISVN 1918

Query: 537  KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
                 E  S   L +TA DG      DTT V++++ +   +   F+ + + A ++E++  
Sbjct: 1919 D--SSELQSHNELKITAFDG---LYKDTTVVKLNITNATKSSLKFEDRAHVATVLENSTS 1973

Query: 597  GTSVSQVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGVIRTNKA-LDRESVATHD 654
               +  + AT     LN  + +  L+P     G F + P+SGV+ T     DRE    +D
Sbjct: 1974 VKILVVLRAT--GTYLNEPLQFTVLNP----HGKFAVIPSSGVLHTTGVPFDREEQDVYD 2027

Query: 655  LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
            +     D  +PP+     V + I+D+ND+ P   +   T  IS+ +  G  + ++ A D 
Sbjct: 2028 VAVEVRDFRSPPRVDVTHVKVYIDDVNDNVPEILNLPKTLLISDETEPGDVLFQVLATDN 2087

Query: 715  DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA--SP 772
            D G N  + +S++  DD   F ++   G    ++     LD+ES   KY L +  +    
Sbjct: 2088 DFGENGSIIFSLE--DDFGLFRIDLYLG----DVSLQRPLDFES-MNKYVLTVLVSDDGQ 2140

Query: 773  PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYR 830
            P  + +   I +   N + P+   FQ ++   K    + PF  +    A   +  +L Y 
Sbjct: 2141 PSLSAIGT-IYIQVQNRSHPI---FQSMYYPLKLPENITPFTTILHVQARNPEGYRLIYN 2196

Query: 831  ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN 874
            +   N + L  ++  TG ++++  L+        + V  TD V+
Sbjct: 2197 LEEDNASRLFNIDFKTGVLSVTDFLDFESETKHILTVRATDSVS 2240



 Score =  175 bits (427), Expect = 1e-41
 Identities = 169/588 (28%), Positives = 274/588 (46%), Gaps = 48/588 (8%)

Query: 103 ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162
           A L+RE    YT+ V+AT+      D  + T  + + ++D ND  P F   +Y V + ED
Sbjct: 99  AVLNREVRDIYTLTVEATESTF---DNRARTKVL-IQVLDTNDLKPLFYPASYHVVIKED 154

Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222
             +  +  + ++ ATDAD+G+N+   Y+         F++D  +G V+LVK LD  Q   
Sbjct: 155 TPIKSS--LVRVSATDADIGSNAEFYYSFT--TRSHPFAVDPFTGTVTLVKRLDTSQRDR 210

Query: 223 YRLVIRAQD-----GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSI- 276
           Y L + A+D      G     N   +++ I+ V  N    +T +   +    + I   I 
Sbjct: 211 YDLTVLAEDRKKKISGVQKFGNVATVVVKIQKVEKN----FTLISPTTAESLLTIDDKIS 266

Query: 277 VRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD-RETQAKYQLL 335
           V ++    ++   A L+    D      + +P         + ++  +D  +      + 
Sbjct: 267 VNIKMEPKEKENTASLSIVKGDPLNCFQI-IPSAFYDGGFQLVSTKFIDWSQNPLGLNIS 325

Query: 336 VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395
           + A D  +PP                    F    Y V L+E  PP T VV ++   + +
Sbjct: 326 LQAKDRSNPPLLTPIKTVHIPPPLQIKPLRFEQELYYVTLSEFSPPKTHVVRVSVGLSLK 385

Query: 396 DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMV 455
           +    + I       +F I+++ G  +I  +Q LDF+    Y   V+A D  G + T ++
Sbjct: 386 NTT--FSIQENPDSYKFKISAKTG--VIVTSQSLDFENRNHYEFDVTAND--GEAVTRVI 439

Query: 456 QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515
            ++ITD N+ AP F    Y AS+ E+  IGT+VL VSA D D   N  +TY+    I+N 
Sbjct: 440 -VDITDENDNAPSFTLPSYQASLPENVRIGTSVLSVSAIDVDKDNNGFVTYA----IANT 494

Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMS-GYLLTVTARDGGVP--SLSDTTDVEISVV 572
                   F I+P TG I+T++  D E M   Y L + A D G P   +S+ T V I++ 
Sbjct: 495 GPV----PFSIDPLTGVISTSQEFDYELMKRWYHLRIWASDSGNPFNRVSECT-VTITMT 549

Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632
           +VNDN PVF++    A+I  D  VG  ++++ A D D     +I Y ++    ++G F I
Sbjct: 550 NVNDNVPVFERVACNASIPRDFAVGEIIAEISALDLDE--LQQIVYRIE-SGNDDGLFSI 606

Query: 633 DPASGVIRTNKAL-----DRESVATHDLKAVAIDGGTPPQSSTVIVHI 675
           DP SG+I+  KA+     D E+ + + LK  A DG      +TV V I
Sbjct: 607 DPVSGIIKLAKAIPSNYKDTEN-SLYTLKITATDGTYIADPNTVTVSI 653



 Score =  166 bits (404), Expect = 7e-39
 Identities = 186/688 (27%), Positives = 295/688 (42%), Gaps = 61/688 (8%)

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           L +    H +++ D+ +  +F+   Y  S+ E+ S     V + ++           I+Y
Sbjct: 8   LGTLTRCHGSLVKDS-SLLRFTHHLYNASIYEN-SAPKTYVESSVRMGILLTDPFWNIKY 65

Query: 190 AIIGGNTQMQFSIDSLS-GDVSLVKTLDYE--------QVRS-YRLVIRAQDGGSPSRSN 239
            I+ G+    F  +    GD S ++ +           +VR  Y L + A +    +R+ 
Sbjct: 66  KIVSGDDDGLFQTEKEDVGDFSFLRIITRSSNSAVLNREVRDIYTLTVEATESTFDNRAR 125

Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
           T ++LI + D ND  P FY + +   + E+ PI  S+VRV A DAD G NAE  Y+ T +
Sbjct: 126 T-KVLIQVLDTNDLKPLFYPASYHVVIKEDTPIKSSLVRVSATDADIGSNAEFYYSFTTR 184

Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD-----GGDPPRSATATXXX 354
            +      P  +DP +G V    +LD   + +Y L V A D      G       AT   
Sbjct: 185 SH------PFAVDPFTGTVTLVKRLDTSQRDRYDLTVLAEDRKKKISGVQKFGNVATVVV 238

Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSI 414
                        P   E  L  D+      V +     +++N     I  G+    F I
Sbjct: 239 KIQKVEKNFTLISPTTAESLLTIDDKIS---VNIKMEPKEKENTASLSIVKGDPLNCFQI 295

Query: 415 TSQ---NGRGLITVAQPLDFKQERRYV-LTVSATD-SGGRSDTAMVQINITDANNYAPV- 468
                 +G   +   + +D+ Q    + +++ A D S     T +  ++I       P+ 
Sbjct: 296 IPSAFYDGGFQLVSTKFIDWSQNPLGLNISLQAKDRSNPPLLTPIKTVHIPPPLQIKPLR 355

Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ-ITYSLSSEISNEAVAHHDQQFVIN 527
           FE   Y  ++ E +P  T V+ VS     VG++ +  T+S+     +        +F I+
Sbjct: 356 FEQELYYVTLSEFSPPKTHVVRVS-----VGLSLKNTTFSIQENPDS-------YKFKIS 403

Query: 528 PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT 587
            +TG I T++ LD E  + Y   VTA DG        T V + + D NDN P F    Y 
Sbjct: 404 AKTGVIVTSQSLDFENRNHYEFDVTANDG-----EAVTRVIVDITDENDNAPSFTLPSYQ 458

Query: 588 ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647
           A++ E+  +GTSV  V A D D   NG + Y +   +     F IDP +GVI T++  D 
Sbjct: 459 ASLPENVRIGTSVLSVSAIDVDKDNNGFVTYAI--ANTGPVPFSIDPLTGVISTSQEFDY 516

Query: 648 ESVAT-HDLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
           E +   + L+  A D G P  + S   V I + ++ND+ PVFE       I  +  +G  
Sbjct: 517 ELMKRWYHLRIWASDSGNPFNRVSECTVTITMTNVNDNVPVFERVACNASIPRDFAVGEI 576

Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY-ESPRKKYE 764
           I EI A D DE    V  Y I+ G+D   FS++   G  K  L   +  +Y ++    Y 
Sbjct: 577 IAEISALDLDELQQIV--YRIESGNDDGLFSIDPVSGIIK--LAKAIPSNYKDTENSLYT 632

Query: 765 LVIRAASPPLWNDVR-VEILVTDVNDNA 791
           L I A       D   V + +TD  + A
Sbjct: 633 LKITATDGTYIADPNTVTVSITDNGEGA 660



 Score =  117 bits (281), Expect = 5e-24
 Identities = 147/579 (25%), Positives = 241/579 (41%), Gaps = 69/579 (11%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I VLD ND  P+F    Y   ++E     ++++ + ATD DIG NAE  Y+         
Sbjct: 130 IQVLDTNDLKPLFYPASYHVVIKEDTPIKSSLVRVSATDADIGSNAEFYYSF----TTRS 185

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS--D 128
           +P                 F +D  +G +     LD  +  RY + V A D+   +S   
Sbjct: 186 HP-----------------FAVDPFTGTVTLVKRLDTSQRDRYDLTVLAEDRKKKISGVQ 228

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
           +  + AT+ V I     N+   S  T      E +   D+ +   IK    +    +++ 
Sbjct: 229 KFGNVATVVVKIQKVEKNFTLISPTT-----AESLLTIDDKISVNIKMEPKEKENTASL- 282

Query: 189 YAIIGGNTQMQFSI---DSLSGDVSLVKT--LDYEQ-VRSYRLVIRAQDGGSPSRSNTTQ 242
            +I+ G+    F I       G   LV T  +D+ Q      + ++A+D  +P      +
Sbjct: 283 -SIVKGDPLNCFQIIPSAFYDGGFQLVSTKFIDWSQNPLGLNISLQAKDRSNPPLLTPIK 341

Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
            +     +     RF   L+  ++SE  P    +VRV       G++ + T T + ++  
Sbjct: 342 TVHIPPPLQIKPLRFEQELYYVTLSEFSPPKTHVVRVSV-----GLSLKNT-TFSIQENP 395

Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
            +    I+   ++G + TS  LD E +  Y+  VTA DG      A              
Sbjct: 396 DSYKFKIS--AKTGVIVTSQSLDFENRNHYEFDVTANDG-----EAVTRVIVDITDENDN 448

Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422
              F    Y+  L E+   GT V++++A D D+DN         NT G    +     G+
Sbjct: 449 APSFTLPSYQASLPENVRIGTSVLSVSAIDVDKDNNGFVTYAIANT-GPVPFSIDPLTGV 507

Query: 423 ITVAQPLDFK-QERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASV 478
           I+ +Q  D++  +R Y L + A+DSG    R     V I +T+ N+  PVFE     AS+
Sbjct: 508 ISTSQEFDYELMKRWYHLRIWASDSGNPFNRVSECTVTITMTNVNDNVPVFERVACNASI 567

Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             D  +G  +  +SA D D     QI Y + S        + D  F I+P +G I   K 
Sbjct: 568 PRDFAVGEIIAEISALDLDE--LQQIVYRIES-------GNDDGLFSIDPVSGIIKLAKA 618

Query: 539 LD---RETMSG-YLLTVTARDGGVPSLSDTTDVEISVVD 573
           +    ++T +  Y L +TA DG    ++D   V +S+ D
Sbjct: 619 IPSNYKDTENSLYTLKITATDG--TYIADPNTVTVSITD 655



 Score =  112 bits (270), Expect = 1e-22
 Identities = 152/594 (25%), Positives = 253/594 (42%), Gaps = 49/594 (8%)

Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
           T+K+  G+    + I  RS     S  L+RE +  Y L V AT+     R+ T       
Sbjct: 78  TEKEDVGDFSF-LRIITRSS---NSAVLNREVRDIYTLTVEATESTFDNRARTKVLIQVL 133

Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITS 416
                    F P  Y V + ED P  + +V ++ATDAD  +   +  +       F++  
Sbjct: 134 DTNDLKPL-FYPASYHVVIKEDTPIKSSLVRVSATDADIGSNAEFYYSFTTRSHPFAVDP 192

Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA 476
             G   +T+ + LD  Q  RY LTV A D   +         +    N A V        
Sbjct: 193 FTGT--VTLVKRLDTSQRDRYDLTVLAEDRKKKIS------GVQKFGNVATVVVKIQKVE 244

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ--FVINPQT---G 531
             F      TT   +   D  + +N ++        ++ ++   D    F I P     G
Sbjct: 245 KNFTLIS-PTTAESLLTIDDKISVNIKMEPKEKENTASLSIVKGDPLNCFQIIPSAFYDG 303

Query: 532 A--ITTNKLLD-RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV-FKQQLYT 587
              + + K +D  +   G  +++ A+D   P L  T    + +      +P+ F+Q+LY 
Sbjct: 304 GFQLVSTKFIDWSQNPLGLNISLQAKDRSNPPLL-TPIKTVHIPPPLQIKPLRFEQELYY 362

Query: 588 ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647
             + E +   T V +V      VGL+ +       ++ +   F I   +GVI T+++LD 
Sbjct: 363 VTLSEFSPPKTHVVRVS-----VGLSLKNTTFSIQENPDSYKFKISAKTGVIVTSQSLDF 417

Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
           E+   ++    A DG    ++ T ++ + I D ND+ P F        + EN  IGT++ 
Sbjct: 418 ENRNHYEFDVTANDG----EAVTRVI-VDITDENDNAPSFTLPSYQASLPENVRIGTSVL 472

Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
            + A D D+  N  V Y+I        FS++   G     + T  + DYE  ++ Y L I
Sbjct: 473 SVSAIDVDKDNNGFVTYAI-ANTGPVPFSIDPLTG----VISTSQEFDYELMKRWYHLRI 527

Query: 768 RAA-SPPLWNDV---RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDAD 822
            A+ S   +N V    V I +T+VNDN PV +      +  +D F VG     + A D D
Sbjct: 528 WASDSGNPFNRVSECTVTITMTNVNDNVPVFERVACNASIPRD-FAVGEIIAEISALDLD 586

Query: 823 VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVP----KLATMEVSVTDG 872
              ++ YRI SGN+  L  ++  +G + L+  + +N       L T++++ TDG
Sbjct: 587 ELQQIVYRIESGNDDGLFSIDPVSGIIKLAKAIPSNYKDTENSLYTLKITATDG 640



 Score = 83.0 bits (196), Expect = 1e-13
 Identities = 77/249 (30%), Positives = 118/249 (47%), Gaps = 33/249 (13%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           +++ D ND++P F +  Y+AS+ E    GT+VL++ A D D   N  V Y I    A+T 
Sbjct: 440 VDITDENDNAPSFTLPSYQASLPENVRIGTSVLSVSAIDVDKDNNGFVTYAI----ANT- 494

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSDR 129
            P                 F ID  +G + T    D E + R Y + + A+D  +P  +R
Sbjct: 495 GPVP---------------FSIDPLTGVISTSQEFDYELMKRWYHLRIWASDSGNPF-NR 538

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           +S   T+ + + + NDN P F       S+  D +V +  +IA+I A D D      I Y
Sbjct: 539 VSE-CTVTITMTNVNDNVPVFERVACNASIPRDFAVGE--IIAEISALDLD--ELQQIVY 593

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTL--DYEQVRS--YRLVIRAQDGGSPSRSNTTQLLI 245
            I  GN    FSID +SG + L K +  +Y+   +  Y L I A DG   +  NT  + +
Sbjct: 594 RIESGNDDGLFSIDPVSGIIKLAKAIPSNYKDTENSLYTLKITATDGTYIADPNT--VTV 651

Query: 246 NIRDVNDNA 254
           +I D  + A
Sbjct: 652 SITDNGEGA 660


>UniRef50_UPI0000F200F1 Cluster: PREDICTED: similar to Fat4; n=3;
            Danio rerio|Rep: PREDICTED: similar to Fat4 - Danio rerio
          Length = 2870

 Score =  369 bits (909), Expect = e-100
 Identities = 386/1494 (25%), Positives = 645/1494 (43%), Gaps = 168/1494 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I++ D ND++P+F    Y  ++ E       +L + ATD+D+G+NA+V Y I        
Sbjct: 1003 IDITDVNDNAPIFSQPVYSVTIPEMKMHEVFILQVSATDRDLGENAQVLYFI-------- 1054

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR--YTVLVKATDQASPVSD 128
            NP +             ++F ++  +G +  + ++   ++    +T +V A+D  + VS 
Sbjct: 1055 NPPN-------------ELFFVNASTGEISNKQTIALAELESEIFTFMVVASDCGN-VS- 1099

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSAI 187
             L+S++ + V ++  N   P F      VS+   + V     + ++ A D D +  N+++
Sbjct: 1100 -LNSSSIVSVALVQYNYFPPMFLPFKPLVSIPLTLDVGSE--VIQVSAVDQDYLQMNNSV 1156

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
             Y   GGN  + F ++  SG V +  TL         L I A+D G P  +  T++   +
Sbjct: 1157 EYFNSGGNGSLYFQVEQNSGRVLVNATLANSLNMILTLEITAKDKGLPPIAAQTEISFEV 1216

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
               N  AP+F  S  +  V E++P+G  I ++Q  D D G N  ++Y+       GN + 
Sbjct: 1217 IQENQFAPQFLNSQVEFFVPEDLPVGSVIGKIQGKDKDVGSNGVISYSFDG----GNENG 1272

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
              +I+  SG +     LD E    + L V A DGG  P+                   F 
Sbjct: 1273 LFSIEHFSGLIMLVKGLDFEKSETHHLSVIAKDGGWRPKKGRLNVTVYVTDLNDNPPIFT 1332

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITV 425
               Y   + E+   GT V+ + A D+D    +++ Y +  G+ +  FS+ S+NG   IT 
Sbjct: 1333 SKDYVASVLENAFIGTLVLQVWAKDSDTGIHSQITYSVIAGDAQ-LFSLDSKNGS--ITT 1389

Query: 426  AQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
             +  D++Q + + LTV AT+ G     D A + I +   N + P F+   Y  SV E   
Sbjct: 1390 LEIFDYEQNQHFELTVKATNIGPPFLFDIARIYIQVVGVNEFIPAFQRHLYNFSVSEALM 1449

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
              T +  + ATD D+G + ++ Y L  +            FV++  TG I   K L    
Sbjct: 1450 PQTEIGSILATDYDLGPDGEVFYILVGQSKKS-------NFVVDKHTGKIYIAKDLKTRL 1502

Query: 544  MSGYLLTVTARD-GGVPSLS-DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
             +  +L V A++ G +   + D   + +S++D ND  P F   LY   + ED  +GTS++
Sbjct: 1503 KNEDVLHVLAKNRGAITGFNVDEALIHLSILDEND-PPEFDSMLYIVAVSEDISIGTSIA 1561

Query: 602  QVGATDADVGLN-GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
            +V A D DV L   R  Y ++       SF+IDP SGVI  N  LDRE  A ++L  +A+
Sbjct: 1562 KVKAVDPDVILEWSRFSYSIE-HGNINSSFIIDPVSGVISVNSHLDREIWAIYNLTVIAV 1620

Query: 661  DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
            D G+P  + +  V I + DINDSPP   +     +I EN P  T +  + A D D  PN 
Sbjct: 1621 DEGSPSVTGSTKVAITVNDINDSPPKLLTT--EGFIRENQPADTLVSTLTATDDDLPPNQ 1678

Query: 721  --VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPRKKYELVIR-AASPPLWN 776
                ++ ++  +    FSL T     +  LVT    D E  P     +V++ A  PP+ +
Sbjct: 1679 GPFTYWMMRPAE---GFSLTT-----EGVLVTSKPFDREHDPLFHMHIVVQDAGKPPMSS 1730

Query: 777  DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNN 836
                 I V D NDNAPV ++  I+   Y   FP G  G V   D D  D     I +G  
Sbjct: 1731 TTLFHIKVLDENDNAPVPRNINILVKYYGSSFPGGLIGNVRPTDLDELDVFNCTIRNG-Q 1789

Query: 837  ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN-EIKAMMQLSVRLITEEMLLNS 895
              +        ++  SP        ++   V  +D ++  +   + ++ +  T   L N 
Sbjct: 1790 PRMFSFPFGMCNLWSSPYQGEATYNIS---VEASDQLHPSVNNSIYVNYKGFTNVSLDNC 1846

Query: 896  ITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNV-SFSAR 954
            +   ++  T E+FLS     F+  L ++        ++F ++   D    +  V S++ +
Sbjct: 1847 VLFYVSISTLEEFLSLKYLKFVKALDSLFNLQASKTHVFGMKLQGDKMLLLAAVKSYNGQ 1906

Query: 955  RPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECL 1014
                EV  +G  S             +H+  L   + V +     N C+  PC N   C 
Sbjct: 1907 YLTGEV-ASGISS-------------MHKKLLEAQSNVTISQITSNPCMLRPCHNGATCN 1952

Query: 1015 TVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETIL---TKASCEVDGD-- 1069
              +        + S S++F   Y +  F C CP GFTG  CE       K  CE  G+  
Sbjct: 1953 RNIHISQEVAVLESSSLIFVSPYFMEIFNCTCPTGFTGDACELDFDECAKEPCENGGNCY 2012

Query: 1070 ---GS-ICR-----SGSQCVA-----------------RREGGILCQGCSIDAAYTTAV- 1102
               G+  C+     SG  C                    R+GG +C  CS      + V 
Sbjct: 2013 NNPGTYFCQCKEGFSGPHCTIVDNECQTVVCLNGGTCWNRQGGFICD-CSPGYEGVSGVN 2071

Query: 1103 CELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSS 1162
            C+ ++  F   S++ +P L  ++   + L+FAT   + LLLYN       DFLALE++S 
Sbjct: 2072 CDEQSYGFQELSYIEYPPLDPQYNF-IYLEFATVQQNALLLYNHGKPSTSDFLALEILS- 2129

Query: 1163 EAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKVLSLA 1222
              GR     L  S+ LG G   +     + DG +H + +       ++ +D+C    S+ 
Sbjct: 2130 --GR-----LFLSYDLGSGVIRLETGKIIADGLFHNISM------ASLEIDNC----SVY 2172

Query: 1223 GAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSF--QVKNKD 1280
                F      A   ++ L    E+ +            +  GG+ +I +    Q++  D
Sbjct: 2173 EPQGFCTTQTGATGNQRTL----EVSSNN----------MTFGGVKSIDAILLRQIRTHD 2218

Query: 1281 FVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKR-SRCSSAPCYNGAECSDLWDTYICDC 1339
            FVGC+ +  +++   D    +A +  L  CP      C +A C N   C D W  + C C
Sbjct: 2219 FVGCMRNLQVNNIRPDSLKSLASHNILPRCPRTDIPPCEAAVCLNEGVCQDQWSHHRCQC 2278

Query: 1340 KEGHTGKDCADSTGPP--WRFGGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVM-SIQ 1396
            ++  TG  CA +          G+  + F+      +   L A+    ++ D+    S++
Sbjct: 2279 RDHFTGPSCAMNLAEQHVLFLNGEAYVKFDVKESYRRNQLLQAILDSGKEGDSLGFDSVE 2338

Query: 1397 LK-----SGLLHYSY----NGETMYLPM-ATLSDGAWHRIEIKWLGTDISVTVD 1440
            +K      G   Y +    +G  + L +   +SDG WH + ++  G+  S+ +D
Sbjct: 2339 IKMRTISDGKPLYMFTNVTSGHQLELSVEGNVSDGQWHVLHLRRRGSLFSLFLD 2392



 Score =  331 bits (814), Expect = 1e-88
 Identities = 257/846 (30%), Positives = 403/846 (47%), Gaps = 69/846 (8%)

Query: 13   VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72
            V D NDH+P F    Y  SV E A  GT +L + A+D+DIG N  V ++I          
Sbjct: 287  VEDVNDHNPEFTQSIYSLSVYEDAPRGTILLKVGASDRDIGPNGLVRFSIS--------- 337

Query: 73   EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132
                          +  F +D   G +L    +DREK   Y+  V A DQ      + S+
Sbjct: 338  --------------ESGFMVDSVLGIVLVIEKMDREKTPFYSFSVFAVDQGDV---QRST 380

Query: 133  TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192
            TATI++ ++D ND  P F  ++  + V E+     +    +I A+D D+GAN  + Y+I 
Sbjct: 381  TATINITVLDVNDCVPNFLPESLIIHVLEN-GEDSSQHTHQIHASDEDLGANGQLTYSIE 439

Query: 193  GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252
             GN +  FS+ S +G + +++ LD E    Y L + A D G PS + T  L+I + D+ND
Sbjct: 440  SGNDENLFSLHS-NGTIQILEDLDREVKSQYVLKVIAVDSGFPSLTGTGTLIIVVDDIND 498

Query: 253  NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312
            N P F   +F   V E+ P+G S +R+ A D D+G   +L Y++        +D P  I+
Sbjct: 499  NIPVFEKDIFTAHVLEDSPVGTSFLRITASDLDDGTIGQLRYSLE------GLDFPFFIN 552

Query: 313  PRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSATATXXXXXXXXXXXXXXFMPGQY 371
              SG ++T   LDRET   Y+ LV  +DG    P S++A               F+ G Y
Sbjct: 553  ATSGDLFTVSALDRETVPFYRFLVIVSDGHPTMPLSSSAAVVVTIEDVNDNFPSFLYGPY 612

Query: 372  EVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
               +      G+ V T+ A DAD +   +L++ + G +    FSI S    G + ++  +
Sbjct: 613  VANIPFGLTKGSVVCTVMAEDADVELNAKLNFSLQGQHAH-LFSINSHT--GTVLISDSI 669

Query: 430  DFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
            + + +    + V       + DT  + +   + ++Y P      Y  S+FEDAPIGT V 
Sbjct: 670  NRRNDITIDVHVQDGAEMPKMDTTTLTVRFWN-DSYFPKIAVQVYKNSLFEDAPIGTLVA 728

Query: 490  VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
            +V+A   +   N  + + L S        +  + F ++P TG +T    LD ET   + L
Sbjct: 729  IVTA---ETLKNVSVYFYLPS-------GNFGEVFELHPSTGELTIKDPLDFETNMYFHL 778

Query: 550  TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
             V ARD G+P  S   ++ +++ DVNDN PVF Q +Y   + E+ L  + V  V A DAD
Sbjct: 779  IVEARDSGIPPFSSYAELHLNISDVNDNPPVFSQDIYKCQVYEN-LASSRVCNVLAKDAD 837

Query: 610  VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669
             G+   + Y +      E +F ID   G + T K LDRE +  ++L   AID       +
Sbjct: 838  SGVFAEVLYFI-LGGNIESTFKIDKNRGTLSTTKRLDREQIPYYNLSIKAIDKENNSLLA 896

Query: 670  TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729
               + +++ D ND  P F    +T  + EN+PIG ++ +I A D D G NAV+ Y+I G 
Sbjct: 897  VASIIVEVLDTNDHAPRFTKIYVT-EVPENAPIGFSVIQIVATDEDAGLNAVIEYTIIGH 955

Query: 730  DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN-DVRVEILVTDVN 788
            +    FS++   G+    L     LD E   + + +V   A+   W+    V I +TDVN
Sbjct: 956  NSEFPFSIDKTTGT----LFVSHPLDRED--QDHYIVKVNANDSAWSISTDVTIDITDVN 1009

Query: 789  DNAPVMKD--FQIIFNNYK--DCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNE 844
            DNAP+     + +     K  + F +    +V A D D+ +  Q          L  +N 
Sbjct: 1010 DNAPIFSQPVYSVTIPEMKMHEVFIL----QVSATDRDLGENAQVLYFINPPNELFFVNA 1065

Query: 845  TTGSMT 850
            +TG ++
Sbjct: 1066 STGEIS 1071



 Score =  316 bits (776), Expect = 6e-84
 Identities = 244/882 (27%), Positives = 409/882 (46%), Gaps = 47/882 (5%)

Query: 18   DHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXX 77
            D + + +M     +VR    S    + ++     + ++A +   + +VTA+TL  ++   
Sbjct: 683  DGAEMPKMDTTTLTVRFWNDSYFPKIAVQVYKNSLFEDAPIGTLVAIVTAETL--KNVSV 740

Query: 78   XXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIH 137
                      +VF +   +G L  +  LD E    + ++V+A D   P     SS A +H
Sbjct: 741  YFYLPSGNFGEVFELHPSTGELTIKDPLDFETNMYFHLIVEARDSGIPP---FSSYAELH 797

Query: 138  VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQ 197
            +NI D NDN P FS+  Y   V E+++ +    +  + A DAD G  + + Y I+GGN +
Sbjct: 798  LNISDVNDNPPVFSQDIYKCQVYENLASSR---VCNVLAKDADSGVFAEVLYFILGGNIE 854

Query: 198  MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF 257
              F ID   G +S  K LD EQ+  Y L I+A D  + S      +++ + D ND+APRF
Sbjct: 855  STFKIDKNRGTLSTTKRLDREQIPYYNLSIKAIDKENNSLLAVASIIVEVLDTNDHAPRF 914

Query: 258  YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317
             T ++   V EN PIG+S++++ A D D G+NA + YT+       N + P +ID  +G 
Sbjct: 915  -TKIYVTEVPENAPIGFSVIQIVATDEDAGLNAVIEYTIIGH----NSEFPFSIDKTTGT 969

Query: 318  VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377
            ++ S  LDRE Q  Y + V A D      S +                F    Y V + E
Sbjct: 970  LFVSHPLDREDQDHYIVKVNANDSA---WSISTDVTIDITDVNDNAPIFSQPVYSVTIPE 1026

Query: 378  DEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435
             +     ++ ++ATD D  E+ ++ Y I   N    F + +  G         L   +  
Sbjct: 1027 MKMHEVFILQVSATDRDLGENAQVLYFINPPNEL--FFVNASTGEISNKQTIALAELESE 1084

Query: 436  RYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
             +   V A+D G  S   +++V + +   N + P+F       S+     +G+ V+ VSA
Sbjct: 1085 IFTFMVVASDCGNVSLNSSSIVSVALVQYNYFPPMFLPFKPLVSIPLTLDVGSEVIQVSA 1144

Query: 494  TDSD-VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552
             D D + +N  + Y  S         +    F +   +G +  N  L         L +T
Sbjct: 1145 VDQDYLQMNNSVEYFNSG-------GNGSLYFQVEQNSGRVLVNATLANSLNMILTLEIT 1197

Query: 553  ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612
            A+D G+P ++  T++   V+  N   P F        + ED  VG+ + ++   D DVG 
Sbjct: 1198 AKDKGLPPIAAQTEISFEVIQENQFAPQFLNSQVEFFVPEDLPVGSVIGKIQGKDKDVGS 1257

Query: 613  NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672
            NG I Y  D  + E G F I+  SG+I   K LD E   TH L  +A DGG  P+   + 
Sbjct: 1258 NGVISYSFDGGN-ENGLFSIEHFSGLIMLVKGLDFEKSETHHLSVIAKDGGWRPKKGRLN 1316

Query: 673  VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732
            V + + D+ND+PP+F S      + EN+ IGT + ++ A D D G ++ + YS+  G D+
Sbjct: 1317 VTVYVTDLNDNPPIFTSKDYVASVLENAFIGTLVLQVWAKDSDTGIHSQITYSVIAG-DA 1375

Query: 733  NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--PPLWNDV-RVEILVTDVND 789
              FSL+++ GS    + T+   DYE   + +EL ++A +  PP   D+ R+ I V  VN+
Sbjct: 1376 QLFSLDSKNGS----ITTLEIFDYEQ-NQHFELTVKATNIGPPFLFDIARIYIQVVGVNE 1430

Query: 790  NAPVMKDFQIIFNNYKDCFPVGPFGRVPA--YDADVTDKLQYRILSGNNANLILLNETTG 847
              P  +     F+  +   P    G + A  YD     ++ Y ++  +  +  ++++ TG
Sbjct: 1431 FIPAFQRHLYNFSVSEALMPQTEIGSILATDYDLGPDGEVFYILVGQSKKSNFVVDKHTG 1490

Query: 848  SMTLSPQLNTNVPKLATMEV-----SVTDGVNEIKAMMQLSV 884
             + ++  L T +     + V         G N  +A++ LS+
Sbjct: 1491 KIYIAKDLKTRLKNEDVLHVLAKNRGAITGFNVDEALIHLSI 1532



 Score =  308 bits (755), Expect = 2e-81
 Identities = 261/875 (29%), Positives = 404/875 (46%), Gaps = 71/875 (8%)

Query: 12  NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71
           NV++ ND+ PVF    + AS+ E +  G   L+L  +D D G   EVE     VT+  L 
Sbjct: 76  NVINVNDNPPVFSQNAFYASIPEDSPVGMCFLSLNVSDPDEGIYGEVELA---VTSGDL- 131

Query: 72  PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131
                          ++ F I+ + G L   A LDRE  A Y+++V+A D A P   RLS
Sbjct: 132 ---------------ENKFSIN-QEGTLCLIAELDRETNAMYSLIVQANDHALPTETRLS 175

Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191
           S+  + + + D NDN P F     TVS  E+  +     +  I+ATDAD G+N    ++ 
Sbjct: 176 SSVHVTIYLKDVNDN-PPFITTPSTVSFPENAPL--QSAVTVIQATDADAGSNGEFVFSF 232

Query: 192 IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251
                +  FSI+S +G V L K LD E     R++++ +D G P       L + + DVN
Sbjct: 233 ESAKDE-SFSINSSTGVVYLQKPLDRETKDVIRVMLKVKDKGIPPLYTLMNLTVLVEDVN 291

Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311
           D+ P F  S++  SV E+ P G  +++V A D D G N  + +++++  +         +
Sbjct: 292 DHNPEFTQSIYSLSVYEDAPRGTILLKVGASDRDIGPNGLVRFSISESGF--------MV 343

Query: 312 DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ- 370
           D   G V    ++DRE    Y   V A D GD  RS TAT              F+P   
Sbjct: 344 DSVLGIVLVIEKMDREKTPFYSFSVFAVDQGDVQRSTTATINITVLDVNDCVPNFLPESL 403

Query: 371 --YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
             + +E  ED    T  +  +  D   + +L Y I  GN    FS+ S    G I + + 
Sbjct: 404 IIHVLENGEDSSQHTHQIHASDEDLGANGQLTYSIESGNDENLFSLHS---NGTIQILED 460

Query: 429 LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
           LD + + +YVL V A DSG    + T  + I + D N+  PVFE   +TA V ED+P+GT
Sbjct: 461 LDREVKSQYVLKVIAVDSGFPSLTGTGTLIIVVDDINDNIPVFEKDIFTAHVLEDSPVGT 520

Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
           + L ++A+D D G   Q+ YSL            D  F IN  +G + T   LDRET+  
Sbjct: 521 SFLRITASDLDDGTIGQLRYSLEG---------LDFPFFINATSGDLFTVSALDRETVPF 571

Query: 547 YLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
           Y   V   DG     LS +  V +++ DVNDN P F    Y ANI      G+ V  V A
Sbjct: 572 YRFLVIVSDGHPTMPLSSSAAVVVTIEDVNDNFPSFLYGPYVANIPFGLTKGSVVCTVMA 631

Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
            DADV LN ++++ L  + +    F I+  +G +  + +++R +  T D+     DG   
Sbjct: 632 EDADVELNAKLNFSL--QGQHAHLFSINSHTGTVLISDSINRRNDITIDVHVQ--DGAEM 687

Query: 666 PQSSTVIVHIKIEDINDSP-PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
           P+  T  + ++    NDS  P          + E++PIGT +  + A   +   N  V++
Sbjct: 688 PKMDTTTLTVRF--WNDSYFPKIAVQVYKNSLFEDAPIGTLVAIVTA---ETLKNVSVYF 742

Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVE 781
            +  G+    F L    G    EL     LD+E+    + L++ A     PP  +   + 
Sbjct: 743 YLPSGNFGEVFELHPSTG----ELTIKDPLDFET-NMYFHLIVEARDSGIPPFSSYAELH 797

Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANL 839
           + ++DVNDN PV          Y++         V A DAD  V  ++ Y IL GN  + 
Sbjct: 798 LNISDVNDNPPVFSQDIYKCQVYEN-LASSRVCNVLAKDADSGVFAEVLYFILGGNIEST 856

Query: 840 ILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN 874
             +++  G+++ + +L+        + +   D  N
Sbjct: 857 FKIDKNRGTLSTTKRLDREQIPYYNLSIKAIDKEN 891



 Score =  297 bits (730), Expect = 2e-78
 Identities = 237/791 (29%), Positives = 380/791 (48%), Gaps = 56/791 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + VLD NDH+P F  + Y   V E A  G +V+ + ATD+D G NA +EYTI  +  ++ 
Sbjct: 902  VEVLDTNDHAPRF-TKIYVTEVPENAPIGFSVIQIVATDEDAGLNAVIEYTI--IGHNSE 958

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             P                 F ID  +G L     LDRE    Y V V A D A  +S   
Sbjct: 959  FP-----------------FSIDKTTGTLFVSHPLDREDQDHYIVKVNANDSAWSIS--- 998

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
                 + ++I D NDN P FS+  Y+V++ E         I ++ ATD D+G N+ + Y 
Sbjct: 999  ---TDVTIDITDVNDNAPIFSQPVYSVTIPE--MKMHEVFILQVSATDRDLGENAQVLYF 1053

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS--YRLVIRAQDGGSPSRSNTTQLLINIR 248
            I   N    F +++ +G++S  +T+   ++ S  +  ++ A D G+ S ++++ + + + 
Sbjct: 1054 INPPNE--LFFVNASTGEISNKQTIALAELESEIFTFMVVASDCGNVSLNSSSIVSVALV 1111

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
              N   P F       S+   + +G  +++V A D D     ++  ++   +  GN  L 
Sbjct: 1112 QYNYFPPMFLPFKPLVSIPLTLDVGSEVIQVSAVDQD---YLQMNNSVEYFNSGGNGSLY 1168

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
              ++  SG V  +  L         L +TA D G PP +A                 F+ 
Sbjct: 1169 FQVEQNSGRVLVNATLANSLNMILTLEITAKDKGLPPIAAQTEISFEVIQENQFAPQFLN 1228

Query: 369  GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
             Q E  + ED P G+ +  +   D D   +  + Y   GGN  G FSI  ++  GLI + 
Sbjct: 1229 SQVEFFVPEDLPVGSVIGKIQGKDKDVGSNGVISYSFDGGNENGLFSI--EHFSGLIMLV 1286

Query: 427  QPLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPI 484
            + LDF++   + L+V A D G R       V + +TD N+  P+F +  Y ASV E+A I
Sbjct: 1287 KGLDFEKSETHHLSVIAKDGGWRPKKGRLNVTVYVTDLNDNPPIFTSKDYVASVLENAFI 1346

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            GT VL V A DSD GI++QITYS+        +A   Q F ++ + G+ITT ++ D E  
Sbjct: 1347 GTLVLQVWAKDSDTGIHSQITYSV--------IAGDAQLFSLDSKNGSITTLEIFDYEQN 1398

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
              + LTV A + G P L D   + I VV VN+  P F++ LY  ++ E  +  T +  + 
Sbjct: 1399 QHFELTVKATNIGPPFLFDIARIYIQVVGVNEFIPAFQRHLYNFSVSEALMPQTEIGSIL 1458

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG- 663
            ATD D+G +G + Y L  + + + +FV+D  +G I   K L         L  +A + G 
Sbjct: 1459 ATDYDLGPDGEVFYILVGQSK-KSNFVVDKHTGKIYIAKDLKTRLKNEDVLHVLAKNRGA 1517

Query: 664  -TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN-AV 721
             T       ++H+ I D ND PP F+S      +SE+  IGT+I +++A DPD     + 
Sbjct: 1518 ITGFNVDEALIHLSILDEND-PPEFDSMLYIVAVSEDISIGTSIAKVKAVDPDVILEWSR 1576

Query: 722  VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781
              YSI+ G+ ++SF ++   G     + + +D +  +      + +   SP +    +V 
Sbjct: 1577 FSYSIEHGNINSSFIIDPVSG--VISVNSHLDREIWAIYNLTVIAVDEGSPSVTGSTKVA 1634

Query: 782  ILVTDVNDNAP 792
            I V D+ND+ P
Sbjct: 1635 ITVNDINDSPP 1645



 Score =  270 bits (663), Expect = 3e-70
 Identities = 223/782 (28%), Positives = 360/782 (46%), Gaps = 57/782 (7%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           +F ++  SG  L   +LD E + RY +L            R+     ++ N+I+ NDN P
Sbjct: 31  LFLLNPHSGEFLLSRALDFE-IERYYILTAGAQHGDSELIRVR----VYFNVINVNDNPP 85

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
            FS+  +  S+ ED  V        +  +D D G    +  A+  G+ + +FSI+   G 
Sbjct: 86  VFSQNAFYASIPEDSPV--GMCFLSLNVSDPDEGIYGEVELAVTSGDLENKFSINQ-EGT 142

Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSR---SNTTQLLINIRDVNDNAPRFYTSLFQES 265
           + L+  LD E    Y L+++A D   P+    S++  + I ++DVNDN P F T+    S
Sbjct: 143 LCLIAELDRETNAMYSLIVQANDHALPTETRLSSSVHVTIYLKDVNDNPP-FITTPSTVS 201

Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325
             EN P+  ++  +QA DAD G N E  ++     +    D   +I+  +G VY    LD
Sbjct: 202 FPENAPLQSAVTVIQATDADAGSNGEFVFS-----FESAKDESFSINSSTGVVYLQKPLD 256

Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
           RET+   ++++   D G PP                    F    Y + + ED P GT +
Sbjct: 257 RETKDVIRVMLKVKDKGIPPLYTLMNLTVLVEDVNDHNPEFTQSIYSLSVYEDAPRGTIL 316

Query: 386 VTLTATDADEDNRLHYEITGGNTRGRFSITSQNG------RGLITVAQPLDFKQERRYVL 439
           + + A+D D          G N   RFSI S++G       G++ V + +D ++   Y  
Sbjct: 317 LKVGASDRD---------IGPNGLVRFSI-SESGFMVDSVLGIVLVIEKMDREKTPFYSF 366

Query: 440 TVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT-VLVVSATDS 496
           +V A D G   RS TA + I + D N+  P F        V E+    +     + A+D 
Sbjct: 367 SVFAVDQGDVQRSTTATINITVLDVNDCVPNFLPESLIIHVLENGEDSSQHTHQIHASDE 426

Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556
           D+G N Q+TYS+ S       + H          G I   + LDRE  S Y+L V A D 
Sbjct: 427 DLGANGQLTYSIESGNDENLFSLHSN--------GTIQILEDLDREVKSQYVLKVIAVDS 478

Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616
           G PSL+ T  + I V D+NDN PVF++ ++TA+++ED+ VGTS  ++ A+D D G  G++
Sbjct: 479 GFPSLTGTGTLIIVVDDINDNIPVFEKDIFTAHVLEDSPVGTSFLRITASDLDDGTIGQL 538

Query: 617 HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG-GTPPQSSTVIVHI 675
            Y L+  D     F I+  SG + T  ALDRE+V  +    +  DG  T P SS+  V +
Sbjct: 539 RYSLEGLD---FPFFINATSGDLFTVSALDRETVPFYRFLVIVSDGHPTMPLSSSAAVVV 595

Query: 676 KIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735
            IED+ND+ P F        I      G+ +  + A D D   NA +++S++ G  ++ F
Sbjct: 596 TIEDVNDNFPSFLYGPYVANIPFGLTKGSVVCTVMAEDADVELNAKLNFSLQ-GQHAHLF 654

Query: 736 SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEIL-VTDVNDNAPVM 794
           S+ +  G       T++  D  + R    + +          +    L V   ND+    
Sbjct: 655 SINSHTG-------TVLISDSINRRNDITIDVHVQDGAEMPKMDTTTLTVRFWNDSYFPK 707

Query: 795 KDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQ 854
              Q+  N+  +  P+G    +   +      + + + SGN   +  L+ +TG +T+   
Sbjct: 708 IAVQVYKNSLFEDAPIGTLVAIVTAETLKNVSVYFYLPSGNFGEVFELHPSTGELTIKDP 767

Query: 855 LN 856
           L+
Sbjct: 768 LD 769



 Score =  263 bits (645), Expect = 4e-68
 Identities = 246/875 (28%), Positives = 389/875 (44%), Gaps = 72/875 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND+ PVFE   + A V E +  GT+ L + A+D D G   ++ Y++E       
Sbjct: 491  IVVDDINDNIPVFEKDIFTAHVLEDSPVGTSFLRITASDLDDGTIGQLRYSLE------- 543

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           +   F I+  SG L T ++LDRE V  Y  LV  +D   P    L
Sbjct: 544  --------------GLDFPFFINATSGDLFTVSALDRETVPFYRFLVIVSD-GHPTMP-L 587

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            SS+A + V I D NDN+P F    Y  ++     +T   V+  + A DADV  N+ + ++
Sbjct: 588  SSSAAVVVTIEDVNDNFPSFLYGPYVANI--PFGLTKGSVVCTVMAEDADVELNAKLNFS 645

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            + G +  + FSI+S +G V +  +++  +     + +  QDG    + +TT L   +R  
Sbjct: 646  LQGQHAHL-FSINSHTGTVLISDSIN--RRNDITIDVHVQDGAEMPKMDTTTL--TVRFW 700

Query: 251  NDN-APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            ND+  P+    +++ S+ E+ PIG  +  V    A+   N  + + +     +GN     
Sbjct: 701  NDSYFPKIAVQVYKNSLFEDAPIGTLVAIV---TAETLKNVSVYFYLP----SGNFGEVF 753

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             + P +G +     LD ET   + L+V A D G PP S+ A               F   
Sbjct: 754  ELHPSTGELTIKDPLDFETNMYFHLIVEARDSGIPPFSSYAELHLNISDVNDNPPVFSQD 813

Query: 370  QYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
             Y+ ++ E+    + V  + A DAD      + Y I GGN    F I     RG ++  +
Sbjct: 814  IYKCQVYEN-LASSRVCNVLAKDADSGVFAEVLYFILGGNIESTFKI--DKNRGTLSTTK 870

Query: 428  PLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
             LD +Q   Y L++ A D    S    A + + + D N++AP F    Y   V E+APIG
Sbjct: 871  RLDREQIPYYNLSIKAIDKENNSLLAVASIIVEVLDTNDHAPRFTKI-YVTEVPENAPIG 929

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ-QFVINPQTGAITTNKLLDRETM 544
             +V+ + ATD D G+NA I Y++        + H+ +  F I+  TG +  +  LDRE  
Sbjct: 930  FSVIQIVATDEDAGLNAVIEYTI--------IGHNSEFPFSIDKTTGTLFVSHPLDREDQ 981

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
              Y++ V A D    + S +TDV I + DVNDN P+F Q +Y+  I E  +    + QV 
Sbjct: 982  DHYIVKVNANDS---AWSISTDVTIDITDVNDNAPIFSQPVYSVTIPEMKMHEVFILQVS 1038

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK--ALDRESVATHDLKAVAIDG 662
            ATD D+G N ++ Y ++P +     F ++ ++G I   +  AL            VA D 
Sbjct: 1039 ATDRDLGENAQVLYFINPPNE---LFFVNASTGEISNKQTIALAELESEIFTFMVVASDC 1095

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE-GPNAV 721
            G    +S+ IV + +   N  PP+F        I     +G+ + ++ A D D    N  
Sbjct: 1096 GNVSLNSSSIVSVALVQYNYFPPMFLPFKPLVSIPLTLDVGSEVIQVSAVDQDYLQMNNS 1155

Query: 722  VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR-AASPPLWNDVRV 780
            V Y   GG+ S  F +E   G     LV     +  +     E+  +    PP+     +
Sbjct: 1156 VEYFNSGGNGSLYFQVEQNSG---RVLVNATLANSLNMILTLEITAKDKGLPPIAAQTEI 1212

Query: 781  EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADVTDK--LQYRILSGNNA 837
               V   N  AP   + Q+ F   +D  PVG   G++   D DV     + Y    GN  
Sbjct: 1213 SFEVIQENQFAPQFLNSQVEFFVPED-LPVGSVIGKIQGKDKDVGSNGVISYSFDGGNEN 1271

Query: 838  NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
             L  +   +G + L   L+    +   + V   DG
Sbjct: 1272 GLFSIEHFSGLIMLVKGLDFEKSETHHLSVIAKDG 1306



 Score =  260 bits (636), Expect = 5e-67
 Identities = 200/684 (29%), Positives = 334/684 (48%), Gaps = 42/684 (6%)

Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259
           F ++  SG+  L + LD+E  R Y L   AQ G S       ++  N+ +VNDN P F  
Sbjct: 32  FLLNPHSGEFLLSRALDFEIERYYILTAGAQHGDS--ELIRVRVYFNVINVNDNPPVFSQ 89

Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319
           + F  S+ E+ P+G   + +   D DEG+  E+   +T    +G+++   +I+ + G + 
Sbjct: 90  NAFYASIPEDSPVGMCFLSLNVSDPDEGIYGEVELAVT----SGDLENKFSIN-QEGTLC 144

Query: 320 TSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377
              +LDRET A Y L+V A D   P   R +++               F+     V   E
Sbjct: 145 LIAELDRETNAMYSLIVQANDHALPTETRLSSSVHVTIYLKDVNDNPPFITTPSTVSFPE 204

Query: 378 DEPPGTPVVTLTATDADEDNRLHYEITGGNTRGR-FSITSQNGRGLITVAQPLDFKQERR 436
           + P  + V  + ATDAD  +   +  +  + +   FSI S  G  ++ + +PLD + +  
Sbjct: 205 NAPLQSAVTVIQATDADAGSNGEFVFSFESAKDESFSINSSTG--VVYLQKPLDRETKDV 262

Query: 437 YVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494
             + +   D G      ++ + +   D N++ P F  + Y+ SV+EDAP GT +L V A+
Sbjct: 263 IRVMLKVKDKGIPPLYTLMNLTVLVEDVNDHNPEFTQSIYSLSVYEDAPRGTILLKVGAS 322

Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554
           D D+G N  + +S+S           +  F+++   G +   + +DRE    Y  +V A 
Sbjct: 323 DRDIGPNGLVRFSIS-----------ESGFMVDSVLGIVLVIEKMDREKTPFYSFSVFAV 371

Query: 555 DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS-VSQVGATDADVGLN 613
           D G    S T  + I+V+DVND  P F  +    +++E+    +    Q+ A+D D+G N
Sbjct: 372 DQGDVQRSTTATINITVLDVNDCVPNFLPESLIIHVLENGEDSSQHTHQIHASDEDLGAN 431

Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673
           G++ Y ++    +E  F +  ++G I+  + LDRE  + + LK +A+D G P  + T  +
Sbjct: 432 GQLTYSIE-SGNDENLFSLH-SNGTIQILEDLDREVKSQYVLKVIAVDSGFPSLTGTGTL 489

Query: 674 HIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN 733
            I ++DIND+ PVFE D  T ++ E+SP+GT+   I A D D+G    + YS++G D   
Sbjct: 490 IIVVDDINDNIPVFEKDIFTAHVLEDSPVGTSFLRITASDLDDGTIGQLRYSLEGLDFP- 548

Query: 734 SFSLETRQGSDKAELVTMVDLDYES-PRKKYELVIRAASP--PLWNDVRVEILVTDVNDN 790
            F +    G    +L T+  LD E+ P  ++ +++    P  PL +   V + + DVNDN
Sbjct: 549 -FFINATSG----DLFTVSALDRETVPFYRFLVIVSDGHPTMPLSSSAAVVVTIEDVNDN 603

Query: 791 APVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGS 848
            P       + N             V A DADV    KL +  L G +A+L  +N  TG+
Sbjct: 604 FPSFLYGPYVANIPFGLTKGSVVCTVMAEDADVELNAKLNFS-LQGQHAHLFSINSHTGT 662

Query: 849 MTLSPQLNTNVPKLATMEVSVTDG 872
           + +S  +N       T++V V DG
Sbjct: 663 VLISDSINRR--NDITIDVHVQDG 684



 Score =  120 bits (289), Expect = 6e-25
 Identities = 99/329 (30%), Positives = 156/329 (47%), Gaps = 15/329 (4%)

Query: 501 NAQITYSLSSEISNEAVAHHDQQ--FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558
           + +  YS  ++ S  +V   D    F++NP +G    ++ LD E    Y+LT  A+ G  
Sbjct: 7   HVEAVYSEKNKTSVYSVQEDDGDGLFLLNPHSGEFLLSRALDFEIERYYILTAGAQHGDS 66

Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618
             +     V  +V++VNDN PVF Q  + A+I ED+ VG     +  +D D G+ G +  
Sbjct: 67  ELI--RVRVYFNVINVNDNPPVFSQNAFYASIPEDSPVGMCFLSLNVSDPDEGIYGEVEL 124

Query: 619 ELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ---SSTVIVHI 675
            +   D  E  F I+   G +     LDRE+ A + L   A D   P +   SS+V V I
Sbjct: 125 AVTSGDL-ENKFSIN-QEGTLCLIAELDRETNAMYSLIVQANDHALPTETRLSSSVHVTI 182

Query: 676 KIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735
            ++D+ND+PP F +   T    EN+P+ + +  I+A D D G N    +S +   D  SF
Sbjct: 183 YLKDVNDNPP-FITTPSTVSFPENAPLQSAVTVIQATDADAGSNGEFVFSFESAKD-ESF 240

Query: 736 SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMK 795
           S+ +  G     L   +D + +   +    V     PPL+  + + +LV DVND+ P   
Sbjct: 241 SINSSTG--VVYLQKPLDRETKDVIRVMLKVKDKGIPPLYTLMNLTVLVEDVNDHNPEFT 298

Query: 796 DFQIIFNNYKDCFPVGP-FGRVPAYDADV 823
                 + Y+D  P G    +V A D D+
Sbjct: 299 QSIYSLSVYEDA-PRGTILLKVGASDRDI 326



 Score = 56.4 bits (130), Expect = 1e-05
 Identities = 55/258 (21%), Positives = 99/258 (38%), Gaps = 20/258 (7%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPL 1369
            C    + C +  C NG  C +    +ICDC  G+ G    +     + F     + + PL
Sbjct: 2031 CTIVDNECQTVVCLNGGTCWNRQGGFICDCSPGYEGVSGVNCDEQSYGFQELSYIEYPPL 2090

Query: 1370 LRPIQLPWL-------NALSIRTRQRDAF--VMSIQLKSGLLHYSYNGETMYLPMAT--- 1417
                   +L       NAL +    + +    +++++ SG L  SY+  +  + + T   
Sbjct: 2091 DPQYNFIYLEFATVQQNALLLYNHGKPSTSDFLALEILSGRLFLSYDLGSGVIRLETGKI 2150

Query: 1418 LSDGAWHRIEIKWLGTD-ISVTVDYGLRTVLMPMLANKIQGQY-IGKILIGGLDTTAGLL 1475
            ++DG +H I +  L  D  SV    G  T       N+   +     +  GG+ +   +L
Sbjct: 2151 IADGLFHNISMASLEIDNCSVYEPQGFCTTQTGATGNQRTLEVSSNNMTFGGVKSIDAIL 2210

Query: 1476 ASDVGF--FEGCIQDVRIGTAQSLLNRPTVRENVRDGCQSRAD---CMLSICPPYSKCVT 1530
               +    F GC++++++   +    +     N+   C  R D   C  ++C     C  
Sbjct: 2211 LRQIRTHDFVGCMRNLQVNNIRPDSLKSLASHNILPRC-PRTDIPPCEAAVCLNEGVCQD 2269

Query: 1531 SWDSSTCTCEAGRVGPQC 1548
             W    C C     GP C
Sbjct: 2270 QWSHHRCQCRDHFTGPSC 2287



 Score = 39.9 bits (89), Expect = 0.99
 Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 1/73 (1%)

Query: 1142 LLYNGRYNERHDFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEI 1201
            +L +G+  +   F ++E +       G P   F+    G + E++VEGNV DG WH + +
Sbjct: 2322 ILDSGKEGDSLGFDSVE-IKMRTISDGKPLYMFTNVTSGHQLELSVEGNVSDGQWHVLHL 2380

Query: 1202 EYFNRTITMILDD 1214
                   ++ LDD
Sbjct: 2381 RRRGSLFSLFLDD 2393


>UniRef50_A7SLL0 Cluster: Predicted protein; n=2; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 1781

 Score =  367 bits (904), Expect = 2e-99
 Identities = 317/1111 (28%), Positives = 498/1111 (44%), Gaps = 103/1111 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +NVLD NDH+PVF        V+E   SGTTV+ + A D D+G NA+V Y+  ++   TL
Sbjct: 420  VNVLDQNDHAPVFTPATLTVKVQEDTGSGTTVIKVSAVDGDVGSNADVTYSTGMI---TL 476

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N                       R+ A    ++L    +  Y + V+A +   P     
Sbjct: 477  N-----------------------RAIAFKPFSALPNPNI--YNLTVRARNIYPP---HY 508

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA-DVGANSAIRY 189
             + A I + ++D ND+ P F +  Y +   +D        I +++A D  D G N+ +RY
Sbjct: 509  KADAAIQIEVLDTNDHAPVFIKSVYLLFAVQDAG--SGVSIGRVEAVDKFDYGPNALVRY 566

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
              I GN   +F +   +G+V +  +L  +  ++Y + +RA D G P  S+T  + + + +
Sbjct: 567  EAISGNGTGRFRVAPETGEVLIASSLRDDVNKTYYIRVRASDMGQPKMSDTAGVYVEVTE 626

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
             N + P F  +++Q S +E++ +G +++ V A D D G N E++Y +      GN     
Sbjct: 627  RNLHPPVFSKAVYQTSENEDIAVGSALLTVTATDRDFGRNGEISYDII----AGNSQEYF 682

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             I   +G +Y S  LD E Q  Y L V+ATDGG  P+++ AT              F P 
Sbjct: 683  GIGLTNGSLYVSKPLDYEHQENYSLNVSATDGGKEPKTSYATVRITLRDVNDNNPVFSPI 742

Query: 370  QYEVELAEDEPPGTPVV-TLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVA 426
            +Y  ELAE+  P + VV ++ ATD DE  +  + Y I GG+ + +F I  + G    TV 
Sbjct: 743  EYRCELAENTTPRSVVVCSVRATDRDERGQQSVRYSILGGSGKDKFVIDERTGEIRATVE 802

Query: 427  QPLDFKQERRYVLTVSATDSG-----GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
               DF+      L ++A D G          A V I IT  N + PVF  + +TA+V E+
Sbjct: 803  --FDFEVTMSSFLMIAAKDEGLSPQRTADPPASVHILITGVNEFLPVFVQSVFTATVAEN 860

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
            APIG +VL VSATD D G +  + Y L         + + Q F ++  TG ++ +  LD 
Sbjct: 861  APIGHSVLRVSATDKDKGPDGVVLYHLLG-------SDNQQGFDLDSNTGTLSVSGDLDN 913

Query: 542  ETMSGYLLTVTARD----GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
            E      L V A++       PS      + ++V D ND  P F + +Y+A++ E + +G
Sbjct: 914  ERAGIVTLRVIAKNLFQNSVTPSSVAHATIVVTVTDAND-PPRFLKSVYSAHVTEGSRIG 972

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
              V+ V A D D  +   I Y +   +    +FV+D  +G +RT   LDRE++A + L  
Sbjct: 973  HVVTNVTAVDDDSDIRS-IRYGISAGNTGN-AFVMDAVTGFVRTAAELDREAIAEYRLTV 1030

Query: 658  VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
             A D GTPP +    + + ++DIND+PP          ++EN P GT +  + A DPD  
Sbjct: 1031 TATDNGTPPMTGNATLVVTLDDINDNPPHLTPLPCIGRVTENKPQGTQVMTLNAEDPDLN 1090

Query: 718  PN-AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN 776
            PN     YSI  G D  SF L    G     + T+  LD E  +  Y + I+       +
Sbjct: 1091 PNRGPFKYSI-SGSDYGSFRLNVSSG----VVSTVKSLDREK-QDAYNISIKVTDARGLS 1144

Query: 777  DVR-VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGN 835
             V    I V D NDN P      +  + ++  F  G    V   D D+ D +   +L+  
Sbjct: 1145 AVNFCMIHVEDQNDNRPKATSRDVYVHTFEGKFLGGVVADVRPDDPDIDDLMTCALLNPP 1204

Query: 836  NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNS 895
              N  + +   G+  LS  L  +      + V+ +DG+  +  ++ L     TE  L   
Sbjct: 1205 QNN--IFSFPRGNCELS-SLAYSQDARFDLSVNGSDGLGAVTYLITLRFLGYTETTLQQG 1261

Query: 896  ITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARR 955
            + VRL +     FL+     F   + A +P    +  I SV    +    +++V  S R+
Sbjct: 1262 VVVRLRNTNTRDFLANSYHKFTSAVNATLPSGYSS-QIMSVDSSGE---GLVDVLVSVRQ 1317

Query: 956  PDAEVGVAGDPSPHYSPTHLRERVYLH-RTTLARLATVQVLPFDDNIC-VHEPCLNFEEC 1013
                +              +R+RV  H +  L   + + +   D N C     CLN  EC
Sbjct: 1318 GGTLM--------------IRDRVSGHLKDKLVSSSALDIAAVDYNPCTTGNQCLNGGEC 1363

Query: 1014 LTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSIC 1073
             + ++       V+S  V+          TC C  GFTG  CE  +       D + + C
Sbjct: 1364 SSAIQASRRGHVVSSTPVVMVTAGYTWKITCSCKPGFTGSQCEESVN------DCNPNPC 1417

Query: 1074 RSGSQCVARREGGILCQGCSIDAAYTTAVCE 1104
            R+   C     G      CS    YT  +CE
Sbjct: 1418 RNEGTC-TDNNGSF---KCSCIPGYTGRLCE 1444



 Score =  355 bits (872), Expect = 1e-95
 Identities = 265/872 (30%), Positives = 403/872 (46%), Gaps = 66/872 (7%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V D ND++PVF   ++  S+ E    GTTV+T+ ATD D G NA+V Y          
Sbjct: 3   ITVQDVNDNAPVFTSDEFTVSIAENVDDGTTVITVTATDPDAGDNAKVSYA--------- 53

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                            + F ID  SG + T  + DRE    Y++ V A+D  +P     
Sbjct: 54  ----------TYGGSHGNKFAIDASSGRIYTTGTFDRETKDDYSINVTASDHGNPSK--- 100

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           SST  + V + D+NDN P+F    Y   + ED +V     I  + A+DAD+G N+ + Y+
Sbjct: 101 SSTCVVLVTVADNNDNSPKFPALHYVFDIAEDAAV--GASIGTVSASDADIGENARLTYS 158

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
           I+    +  FS++ ++G++++ + LD E   +Y + + A D G+P  S + ++ + + D 
Sbjct: 159 IVSPE-KATFSMNPVTGEITVGQRLDREGA-NYSIRVTATDLGTPPLSASMEITVIVDDY 216

Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
           ND+ P F + +    + EN   G  I+ +QA D D GVNAE+ Y       TGN +   T
Sbjct: 217 NDHRPVFLSHIGTVFIDENASPGTEIITLQAVDGDSGVNAEIRYAFV----TGNSNNSFT 272

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
           I+  +G + T+  LDRET  ++ L V A D G P + +                 F   +
Sbjct: 273 INSITGRLRTARNLDRETTPRFTLEVLAYDLGVPRKDSVTNVTVVLRDVNDNQPVFTMSE 332

Query: 371 YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
           Y  E++E       +VT+ A D D   D  + Y IT G   G F I      G I +   
Sbjct: 333 YAAEVSEGVVESN-IVTVVAEDRDIGSDGSVTYCITQGREGGLFVINENT--GTIGITAK 389

Query: 429 LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
           LD + + +Y L V ATD G    S  A V +N+ D N++APVF  A  T  V ED   GT
Sbjct: 390 LDRETKSKYTLRVQATDGGSPALSSEADVIVNVLDQNDHAPVFTPATLTVKVQEDTGSGT 449

Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
           TV+ VSA D DVG NA +TYS      N A+A      + NP                  
Sbjct: 450 TVIKVSAVDGDVGSNADVTYSTGMITLNRAIAFKPFSALPNPNI---------------- 493

Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
           Y LTV AR+   P       ++I V+D ND+ PVF + +Y    ++DA  G S+ +V A 
Sbjct: 494 YNLTVRARNIYPPHYKADAAIQIEVLDTNDHAPVFIKSVYLLFAVQDAGSGVSIGRVEAV 553

Query: 607 DA-DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
           D  D G N  + YE        G F + P +G +    +L  +   T+ ++  A D G P
Sbjct: 554 DKFDYGPNALVRYEA-ISGNGTGRFRVAPETGEVLIASSLRDDVNKTYYIRVRASDMGQP 612

Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
             S T  V++++ + N  PPVF         +E+  +G+ +  + A D D G N  + Y 
Sbjct: 613 KMSDTAGVYVEVTERNLHPPVFSKAVYQTSENEDIAVGSALLTVTATDRDFGRNGEISYD 672

Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEI 782
           I  G+    F +    GS    L     LDYE  ++ Y L + A      P  +   V I
Sbjct: 673 IIAGNSQEYFGIGLTNGS----LYVSKPLDYEH-QENYSLNVSATDGGKEPKTSYATVRI 727

Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADV--TDKLQYRILSGNNANL 839
            + DVNDN PV    +      ++  P       V A D D      ++Y IL G+  + 
Sbjct: 728 TLRDVNDNNPVFSPIEYRCELAENTTPRSVVVCSVRATDRDERGQQSVRYSILGGSGKDK 787

Query: 840 ILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            +++E TG +  + + +  V   + + ++  D
Sbjct: 788 FVIDERTGEIRATVEFDFEVTMSSFLMIAAKD 819



 Score =  324 bits (796), Expect = 2e-86
 Identities = 266/887 (29%), Positives = 395/887 (44%), Gaps = 73/887 (8%)

Query: 4    PFCIHQQINVL--DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
            P     +I V+  D NDH PVF        + E AS GT ++TL+A D D G NAE+ Y 
Sbjct: 202  PLSASMEITVIVDDYNDHRPVFLSHIGTVFIDENASPGTEIITLQAVDGDSGVNAEIRYA 261

Query: 62   IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121
               VT ++ N                  F I+  +G L T  +LDRE   R+T+ V A D
Sbjct: 262  --FVTGNSNNS-----------------FTINSITGRLRTARNLDRETTPRFTLEVLAYD 302

Query: 122  QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181
               P   R  S   + V + D NDN P F+   Y   V E + V  N  I  + A D D+
Sbjct: 303  LGVP---RKDSVTNVTVVLRDVNDNQPVFTMSEYAAEVSEGV-VESN--IVTVVAEDRDI 356

Query: 182  GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
            G++ ++ Y I  G     F I+  +G + +   LD E    Y L ++A DGGSP+ S+  
Sbjct: 357  GSDGSVTYCITQGREGGLFVINENTGTIGITAKLDRETKSKYTLRVQATDGGSPALSSEA 416

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
             +++N+ D ND+AP F  +     V E+   G ++++V A D D G NA++TY+      
Sbjct: 417  DVIVNVLDQNDHAPVFTPATLTVKVQEDTGSGTTVIKVSAVDGDVGSNADVTYS------ 470

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
            TG + L   I  +      +  +       Y L V A +   P   A A           
Sbjct: 471  TGMITLNRAIAFKPFSALPNPNI-------YNLTVRARNIYPPHYKADAAIQIEVLDTND 523

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRL-HYEITGGNTRGRFSITSQN 418
                F+   Y +   +D   G  +  + A D  +   N L  YE   GN  GRF +  + 
Sbjct: 524  HAPVFIKSVYLLFAVQDAGSGVSIGRVEAVDKFDYGPNALVRYEAISGNGTGRFRVAPET 583

Query: 419  GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTA 476
            G   + +A  L     + Y + V A+D G    SDTA V + +T+ N + PVF  A Y  
Sbjct: 584  GE--VLIASSLRDDVNKTYYIRVRASDMGQPKMSDTAGVYVEVTERNLHPPVFSKAVYQT 641

Query: 477  SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
            S  ED  +G+ +L V+ATD D G N +I+Y + +  S E        F I    G++  +
Sbjct: 642  SENEDIAVGSALLTVTATDRDFGRNGEISYDIIAGNSQE-------YFGIGLTNGSLYVS 694

Query: 537  KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
            K LD E    Y L V+A DGG    +    V I++ DVNDN PVF    Y   + E+   
Sbjct: 695  KPLDYEHQENYSLNVSATDGGKEPKTSYATVRITLRDVNDNNPVFSPIEYRCELAENTTP 754

Query: 597  -GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655
                V  V ATD D      + Y +     ++  FVID  +G IR     D E   +  L
Sbjct: 755  RSVVVCSVRATDRDERGQQSVRYSILGGSGKD-KFVIDERTGEIRATVEFDFEVTMSSFL 813

Query: 656  KAVAIDGGTPPQSST---VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
               A D G  PQ +      VHI I  +N+  PVF     T  ++EN+PIG ++  + A 
Sbjct: 814  MIAAKDEGLSPQRTADPPASVHILITGVNEFLPVFVQSVFTATVAENAPIGHSVLRVSAT 873

Query: 713  DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI----- 767
            D D+GP+ VV Y + G D+   F L++  G+    L    DLD E        VI     
Sbjct: 874  DKDKGPDGVVLYHLLGSDNQQGFDLDSNTGT----LSVSGDLDNERAGIVTLRVIAKNLF 929

Query: 768  -RAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTD 825
              + +P       + + VTD ND    +K   +   +  +   +G     V A D D   
Sbjct: 930  QNSVTPSSVAHATIVVTVTDANDPPRFLK--SVYSAHVTEGSRIGHVVTNVTAVDDDSDI 987

Query: 826  K-LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            + ++Y I +GN  N  +++  TG +  + +L+        + V+ TD
Sbjct: 988  RSIRYGISAGNTGNAFVMDAVTGFVRTAAELDREAIAEYRLTVTATD 1034



 Score =  324 bits (795), Expect = 3e-86
 Identities = 232/752 (30%), Positives = 357/752 (47%), Gaps = 43/752 (5%)

Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195
           + + + D NDN P F+   +TVS+ E++   D   +  + ATD D G N+ + YA  GG+
Sbjct: 1   VTITVQDVNDNAPVFTSDEFTVSIAENVD--DGTTVITVTATDPDAGDNAKVSYATYGGS 58

Query: 196 TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP 255
              +F+ID+ SG +    T D E    Y + + A D G+PS+S+T  +L+ + D NDN+P
Sbjct: 59  HGNKFAIDASSGRIYTTGTFDRETKDDYSINVTASDHGNPSKSSTCVVLVTVADNNDNSP 118

Query: 256 RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315
           +F    +   ++E+  +G SI  V A DAD G NA LTY++   +         +++P +
Sbjct: 119 KFPALHYVFDIAEDAAVGASIGTVSASDADIGENARLTYSIVSPE-----KATFSMNPVT 173

Query: 316 GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375
           G +    +LDRE  A Y + VTATD G PP SA+                F+     V +
Sbjct: 174 GEITVGQRLDRE-GANYSIRVTATDLGTPPLSASMEITVIVDDYNDHRPVFLSHIGTVFI 232

Query: 376 AEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ 433
            E+  PGT ++TL A D D   +  + Y    GN+   F+I S  GR  +  A+ LD + 
Sbjct: 233 DENASPGTEIITLQAVDGDSGVNAEIRYAFVTGNSNNSFTINSITGR--LRTARNLDRET 290

Query: 434 ERRYVLTVSATDSG-GRSDTAM-VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491
             R+ L V A D G  R D+   V + + D N+  PVF  + Y A V E   + + ++ V
Sbjct: 291 TPRFTLEVLAYDLGVPRKDSVTNVTVVLRDVNDNQPVFTMSEYAAEVSEGV-VESNIVTV 349

Query: 492 SATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTV 551
            A D D+G +  +TY ++              FVIN  TG I     LDRET S Y L V
Sbjct: 350 VAEDRDIGSDGSVTYCITQ-------GREGGLFVINENTGTIGITAKLDRETKSKYTLRV 402

Query: 552 TARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG 611
            A DGG P+LS   DV ++V+D ND+ PVF     T  + ED   GT+V +V A D DVG
Sbjct: 403 QATDGGSPALSSEADVIVNVLDQNDHAPVFTPATLTVKVQEDTGSGTTVIKVSAVDGDVG 462

Query: 612 LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671
            N  + Y         G   ++ A    +   AL   ++  ++L   A +   P   +  
Sbjct: 463 SNADVTY-------STGMITLNRAI-AFKPFSALPNPNI--YNLTVRARNIYPPHYKADA 512

Query: 672 IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP-DEGPNAVVHYSIKGGD 730
            + I++ D ND  PVF       +  +++  G +IG + A D  D GPNA+V Y    G+
Sbjct: 513 AIQIEVLDTNDHAPVFIKSVYLLFAVQDAGSGVSIGRVEAVDKFDYGPNALVRYEAISGN 572

Query: 731 DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDV 787
            +  F +    G      V +     +   K Y + +RA+    P + +   V + VT+ 
Sbjct: 573 GTGRFRVAPETGE-----VLIASSLRDDVNKTYYIRVRASDMGQPKMSDTAGVYVEVTER 627

Query: 788 NDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNET 845
           N + PV        +  +D         V A D D     ++ Y I++GN+     +  T
Sbjct: 628 NLHPPVFSKAVYQTSENEDIAVGSALLTVTATDRDFGRNGEISYDIIAGNSQEYFGIGLT 687

Query: 846 TGSMTLSPQLNTNVPKLATMEVSVTDGVNEIK 877
            GS+ +S  L+    +  ++ VS TDG  E K
Sbjct: 688 NGSLYVSKPLDYEHQENYSLNVSATDGGKEPK 719



 Score = 60.5 bits (140), Expect = 7e-07
 Identities = 73/297 (24%), Positives = 111/297 (37%), Gaps = 53/297 (17%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPL 1369
            C    + C S+PC   + C DL  ++ C C  G  G+ C  S+     FG      F P 
Sbjct: 1481 CDVDINYCQSSPCMYNSTCKDLPTSFECVCDFGGRGERCEISS-----FG------FEPA 1529

Query: 1370 LRPIQLPWLNALSIRTRQRDAFVMSIQLKSGLLHYSYNGETM-------------YLPMA 1416
               +  P L  ++ +T        S    +GLL Y+ +G                YL   
Sbjct: 1530 SYML-FPTLQGVNQKTYNNITMEFSTSSPNGLLFYNTDGTPAAAADFIALEIVERYLCDR 1588

Query: 1417 TLSDGAWHRIEIKWLGTDISVTVDYGLRTVL--MPMLANKIQGQYIGKILIGGLDTTAGL 1474
             ++DG WH + +     D  VT+  G         +  +   G  I +  +GG       
Sbjct: 1589 AVTDGKWHHVTVI---RDKKVTLATGTEFTQREFAVTPHNFLGANIRQWSLGGATQVPSG 1645

Query: 1475 LASDVGFFEGCIQDVRIGTAQSLLNRPT------VREN-VRDGCQSRADCMLSIC---PP 1524
            +  +   F+GC++D++I    + +N P        R   V +GC +   C  S C     
Sbjct: 1646 VTLEK--FKGCMEDLKINGVNTPMNGPNRFLSAEARGGAVTEGCVTSGQCQSSPCANNKE 1703

Query: 1525 YSKCVTSWDSSTCTCEAGRVGPQCVSACELGPC-GAARCVPDQTPKGYSCACEPGYT 1580
             + C   WDS TC   A          C+  PC   A C P Q  + + C C   YT
Sbjct: 1704 KTACYEDWDSYTCVSAA---------PCQPDPCKNNATCKP-QKDETFLCVCVGNYT 1750



 Score = 50.4 bits (115), Expect = 7e-04
 Identities = 26/72 (36%), Positives = 33/72 (45%), Gaps = 4/72 (5%)

Query: 1512 QSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTP 1568
            +S  DC  + C     C  +  S  C+C  G  G  C   +  C   PC  A    D TP
Sbjct: 1407 ESVNDCNPNPCRNEGTCTDNNGSFKCSCIPGYTGRLCESDIDECLTNPCKHASAC-DNTP 1465

Query: 1569 KGYSCACEPGYT 1580
             GY+C C+PGYT
Sbjct: 1466 GGYTCTCKPGYT 1477



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 36/124 (29%), Positives = 59/124 (47%), Gaps = 15/124 (12%)

Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101
            +TC C  G+TG NC+  +    C+     S C   S C    +       C  D      
Sbjct: 1468 YTCTCKPGYTGQNCDVDIN--YCQ----SSPCMYNSTC----KDLPTSFECVCDFGGRGE 1517

Query: 1102 VCELRARSFPVSSFLTFP---GLKRRHRIHLKLKFATQTTSGLLLYN--GRYNERHDFLA 1156
             CE+ +  F  +S++ FP   G+ ++   ++ ++F+T + +GLL YN  G      DF+A
Sbjct: 1518 RCEISSFGFEPASYMLFPTLQGVNQKTYNNITMEFSTSSPNGLLFYNTDGTPAAAADFIA 1577

Query: 1157 LELV 1160
            LE+V
Sbjct: 1578 LEIV 1581



 Score = 41.9 bits (94), Expect = 0.25
 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 5/72 (6%)

Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566
            C+S  D C+ + C   S C  +    TCTC+ G  G  C   ++ C+  PC       D 
Sbjct: 1443 CESDIDECLTNPCKHASACDNTPGGYTCTCKPGYTGQNCDVDINYCQSSPCMYNSTCKD- 1501

Query: 1567 TPKGYSCACEPG 1578
             P  + C C+ G
Sbjct: 1502 LPTSFECVCDFG 1513



 Score = 40.7 bits (91), Expect = 0.57
 Identities = 42/149 (28%), Positives = 57/149 (38%), Gaps = 30/149 (20%)

Query: 1536 TCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKE 1592
            TC+C+ G  G QC   V+ C   PC       D     + C+C PGY   T    ES  +
Sbjct: 1393 TCSCKPGFTGSQCEESVNDCNPNPCRNEGTCTDNN-GSFKCSCIPGY---TGRLCESDID 1448

Query: 1593 ECPGGWWGGSACGPC----ACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648
            EC           PC    ACD T G +         C CK  +       +   CQ  +
Sbjct: 1449 EC--------LTNPCKHASACDNTPGGY--------TCTCKPGYTGQNCDVDINYCQS-S 1491

Query: 1649 AGSENSSCE--AATGQCHCRPGVIGRACD 1675
                NS+C+    + +C C  G  G  C+
Sbjct: 1492 PCMYNSTCKDLPTSFECVCDFGGRGERCE 1520



 Score = 37.9 bits (84), Expect = 4.0
 Identities = 13/39 (33%), Positives = 20/39 (51%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C + PC + + C +    Y C CK G+TG++C
Sbjct: 1443 CESDIDECLTNPCKHASACDNTPGGYTCTCKPGYTGQNC 1481



 Score = 37.1 bits (82), Expect = 7.0
 Identities = 40/130 (30%), Positives = 54/130 (41%), Gaps = 32/130 (24%)

Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENG--KCHCK 1629
            +C+C+PG+T   S C ES  +  P          PC  + T      C   NG  KC C 
Sbjct: 1393 TCSCKPGFT--GSQCEESVNDCNPN---------PCRNEGT------CTDNNGSFKCSCI 1435

Query: 1630 ENHYK---PEGTAECLPCQCYAAGSENSSCEAATG--QCHCRPGVIGRACDACANAYAEV 1684
              +          ECL   C  A    S+C+   G   C C+PG  G+ CD   N Y + 
Sbjct: 1436 PGYTGRLCESDIDECLTNPCKHA----SACDNTPGGYTCTCKPGYTGQNCDVDIN-YCQS 1490

Query: 1685 TP---NSGCE 1691
            +P   NS C+
Sbjct: 1491 SPCMYNSTCK 1500



 Score = 37.1 bits (82), Expect = 7.0
 Identities = 14/39 (35%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C E  + C+  PC N   C+D   ++ C C  G+TG+ C
Sbjct: 1405 CEESVNDCNPNPCRNEGTCTDNNGSFKCSCIPGYTGRLC 1443


>UniRef50_Q24292 Cluster: Protein dachsous precursor; n=3; Drosophila
            melanogaster|Rep: Protein dachsous precursor - Drosophila
            melanogaster (Fruit fly)
          Length = 3503

 Score =  359 bits (884), Expect = 5e-97
 Identities = 254/789 (32%), Positives = 395/789 (50%), Gaps = 70/789 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I V D ND++P +     +  V E    GT +    ATD D G N +++Y + +     
Sbjct: 1419 KIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRL-IRYFPQ 1477

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            LN                 +FR+D  +GAL  +A LD E V  Y ++V+A DQ+S V++R
Sbjct: 1478 LNESQEQA---------MSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTER 1528

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTD----NPVIAKIKATDADVGANS 185
            L ++ T+ + I+D ND+ P F     +      + ++D      V+A I A D D G N 
Sbjct: 1529 LQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNG 1588

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKTL-----DYEQVRSYRLVIRAQDGGSPS-RSN 239
             + Y I GGN + +F I+S +G + LVK+L     D E+   + L+I A+D G P  + +
Sbjct: 1589 QLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKS 1648

Query: 240  TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
            +  L + ++  ++N PRF  ++++ ++ ENVP G  +++V A       NA L+Y +   
Sbjct: 1649 SLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIP-- 1706

Query: 300  DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG------------------ 341
               G  +    +D + G + T GQ DRE+QA Y L V   D                   
Sbjct: 1707 --AGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSD 1764

Query: 342  --GDPPRSA---TATXXXXXXXXXXXXXXFMPGQ-YEVELAEDEPPGTPVVTLTATDADE 395
              GD         AT              F PG  Y + + E+  PG  + T+ A+D DE
Sbjct: 1765 SIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGV-IHTVVASDLDE 1823

Query: 396  DNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG---GRS 450
                 L Y ITGGN   +FSI S +G      A+PLD +Q  RY L + A+D G    R 
Sbjct: 1824 GPNADLIYSITGGNLGNKFSIDSSSGE---LSARPLDREQHSRYTLQIQASDRGQPKSRQ 1880

Query: 451  DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510
                + I + D N+ AP F+ + YT SV EDAP+GT+V+ +SA D+D+G+NA++ YSL++
Sbjct: 1881 GHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLAN 1940

Query: 511  EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL-SDTTDVEI 569
            E           QF I+ Q+G ITT   LDRE  + Y   V A DGG   + S T  V+I
Sbjct: 1941 ET--------QWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQI 1992

Query: 570  SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE-EG 628
            +V+D+NDN P+F++  Y   +      G ++ +V A DAD+G N  I Y L+ ++     
Sbjct: 1993 NVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSA 2052

Query: 629  SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV-- 686
             F I+P++G +  +++L  ES     L+ VA D G PPQSS  ++ + I +     PV  
Sbjct: 2053 KFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLR 2112

Query: 687  FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746
            F+++     + ENSP GT + ++ A   D G    V +S   G++    SL++  G  + 
Sbjct: 2113 FQNETYRVMLKENSPSGTRLLQVVALRSD-GRRQKVQFSFGAGNEDGILSLDSLSGEIRV 2171

Query: 747  ELVTMVDLD 755
                ++D D
Sbjct: 2172 NKPHLLDYD 2180



 Score =  332 bits (816), Expect = 8e-89
 Identities = 290/928 (31%), Positives = 434/928 (46%), Gaps = 96/928 (10%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVRE-----GASSGTTVLTLKATDQDIGKNAEVEYTIEL 64
            ++ + D ND+ PVF  ++Y+ S+RE       +S T ++ + ATD D G   +V Y I  
Sbjct: 649  KMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRI-- 706

Query: 65   VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVL-VKATDQ 122
            V  +                    +FRID  +G + + R  +   +     +L + ATD 
Sbjct: 707  VAGNEAG-----------------IFRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDG 749

Query: 123  ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
             +    R ++ A + ++IID     P F +  Y   V EDI      V+  + A   DV 
Sbjct: 750  GNL---RSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDI--PRGTVVGSVIAASGDVA 804

Query: 183  ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
              S +RY+I  G+    FSI++ SG++ + K LD+E      L I+A  G  P   + TQ
Sbjct: 805  HRSPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYGH-TQ 863

Query: 243  LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
            + I + DVNDNAP F  S+ + SV E+  +G  +    A+D D G + ++TY++  +   
Sbjct: 864  VNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGK 923

Query: 303  GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
            G       ID RSG +  S  LD E+  ++ L+VTATDGG P  S   T           
Sbjct: 924  G----LFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDN 979

Query: 363  XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEIT-GGNTRGRFSITSQN- 418
               F   +Y V ++E       ++ + A+D D  N  R+ Y I   G      SI+S + 
Sbjct: 980  PPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDV 1039

Query: 419  --------GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPV 468
                      G I +  PLD +   RY LTV ATD+G  +  A   V + + DAN+  P 
Sbjct: 1040 SQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPK 1099

Query: 469  FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528
            F+ + Y   + E+   G+ V VV+A+D D+G NA I YSL    S+         F ++P
Sbjct: 1100 FQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSS---------FQVHP 1150

Query: 529  QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP-VFKQQLYT 587
             TG I+T + LDRE    Y L V ARD G P  S    V I V DVNDN P +   Q   
Sbjct: 1151 VTGEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDV 1210

Query: 588  ANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDRE-EGSFVIDPASGVIRTNKAL 645
             ++ E+   GT V +V A D D G N  I Y +   +D +  G F IDP SGVIRT   L
Sbjct: 1211 VSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVL 1270

Query: 646  DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
            D E  + + L   A DGG PP+ +  ++ +++ D+ND+ P F S  L F + E++ +G  
Sbjct: 1271 DHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHV 1330

Query: 706  IGEIRAHDPDEGPNAVVHYSIKGGDDS-------NSFS---LETRQGSDK--AELVTMVD 753
            +G I    P E P  VV  S++   +        N  +   +E     D+    LV    
Sbjct: 1331 VGSI---SPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARL 1387

Query: 754  LDYESPRKKYELVIR-----AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCF 808
            LD E  + ++ L IR     A++ P  + + V+I V DVNDNAP      I      +  
Sbjct: 1388 LDRE-VQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDL-QVSEAT 1445

Query: 809  PVGP-FGRVPAYDAD--VTDKLQYRIL--------SGNNA-NLILLNETTGSMTLSPQLN 856
            PVG       A DAD      LQYR++        S   A +L  ++  TG+++L   L+
Sbjct: 1446 PVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLD 1505

Query: 857  TNVPKLATMEVSVTDGVNEIKAMMQLSV 884
                +   + V   D  + +   +Q SV
Sbjct: 1506 FEAVQEYLLIVQALDQSSNVTERLQTSV 1533



 Score =  331 bits (814), Expect = 1e-88
 Identities = 269/892 (30%), Positives = 404/892 (45%), Gaps = 82/892 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            ++++D     P+FE  +Y   V+E    GT V ++ A   D+   + V Y+I     D  
Sbjct: 762  LSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPD-- 819

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F I+  SG +     LD E  ++  + ++AT    PV    
Sbjct: 820  -----------------GYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYGHT 862

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
                 +++ + D NDN P+F      +SV E   +   P+ A   A D D G++  + Y+
Sbjct: 863  Q----VNIEVEDVNDNAPEFEASMVRISVPESAEL-GAPLYAA-HAHDKDSGSSGQVTYS 916

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            ++  + +  F+ID+ SG + L + LDYE  + + L++ A DGG PS S    +L++++DV
Sbjct: 917  LVKESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDV 976

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY--------T 302
            NDN P F    +  +VSE+  I   I++V A D D G NA +TY + D           +
Sbjct: 977  NDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISS 1036

Query: 303  GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
             +V     I P SGW+Y    LDRET+ +YQL V ATD G P   A              
Sbjct: 1037 SDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDN 1096

Query: 363  XXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGR 420
               F   +YE  + E+   G+ V  +TA+D D  E+  + Y +   N+   F +    G 
Sbjct: 1097 DPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINS--SFQVHPVTGE 1154

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAP-VFENAPYTAS 477
              I+  +PLD +    Y L V A D G   RS    V+I+++D N+ AP + +      S
Sbjct: 1155 --ISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVS 1212

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            V E+ P GT V+ V A D D G NA ITYS+      ++  H    F I+P +G I T  
Sbjct: 1213 VREEQPPGTEVVRVRAVDRDHGQNASITYSIVK--GRDSDGH--GLFSIDPTSGVIRTRV 1268

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
            +LD E  S Y L V A DGG P       + + V+D+NDN P F        + EDA +G
Sbjct: 1269 VLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALG 1328

Query: 598  TSVSQVGATD--ADVGLNG--------RIHYELDP--KDREEGSFVIDPASGVIRTNKAL 645
              V  +   +  ADV  N         R+ Y L+P  KD  E +F ID  SG +   + L
Sbjct: 1329 HVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLL 1388

Query: 646  DRESVATHDLKAVAID--GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703
            DRE  +   L+  A+D      PQSS + V I++ D+ND+ P +  D +   +SE +P+G
Sbjct: 1389 DREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVG 1448

Query: 704  TTIGEIRAHDPDEGPNAVVHYSI------KGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757
            T I    A D D G N  + Y +             + SL  R  S    L     LD+E
Sbjct: 1449 TIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSL-FRMDSLTGALSLQAPLDFE 1507

Query: 758  SPRKKYELVIRA------ASPPLWNDVRVEILVTDVNDNAPVM-----KDFQIIFNNYKD 806
            +  ++Y L+++A       +  L   V V + + D ND+AP          +       D
Sbjct: 1508 AV-QEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISD 1566

Query: 807  CFPVGP-FGRVPAYDADVTD--KLQYRILSGNNANLILLNETTGSMTLSPQL 855
               +G     + A D D  D  +L Y I  GN      +N  TG + L   L
Sbjct: 1567 ATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSL 1618



 Score =  311 bits (764), Expect = 2e-82
 Identities = 247/830 (29%), Positives = 386/830 (46%), Gaps = 56/830 (6%)

Query: 86  VQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145
           V+    ID  +G + T+  LDRE  A Y+++      A P+S R      + V + D+ND
Sbjct: 66  VETDLAIDRATGEIRTKVKLDRETRASYSLV------AIPLSGR---NIRVLVTVKDEND 116

Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS- 204
           N P F + +  +   E+        +  + A D D+   +  RY I+ GN    F + S 
Sbjct: 117 NAPTFPQTSMHIEFPENTPREVKRTL--LPARDLDLEPYNTQRYNIVSGNVNDAFRLSSH 174

Query: 205 ------LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY 258
                 L  D+ +   LD E    Y L+I A DGG+P       + I I+DVNDN P F 
Sbjct: 175 RERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFN 234

Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV 318
            S +  +V EN  +G S+++V A D D   N  + Y +  +    + +    IDPR+G +
Sbjct: 235 QSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQ--SDKEQMFRIDPRTGAI 292

Query: 319 YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX----XXXXXFMPGQYEVE 374
           Y +  LD ET+  ++L+V A D G+ P   TA                   F+      +
Sbjct: 293 YINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPK 352

Query: 375 LAEDEPPGTPVVTLTATDADEDNRL-HYEITGGNTRGRFSITSQ-NGRGLITVAQPLDFK 432
           ++E   PG  V  ++  D D      +  +T     G F++T++ N   L+ V  PLD +
Sbjct: 353 ISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDRE 412

Query: 433 QERRYVLTVSATDSGGRSDTAMVQI--NITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
               Y L+V ATD G     A   I   ITD N+  P FE   Y A+V E A  GT+VL 
Sbjct: 413 IVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQ 472

Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550
           V A D D G+N+ +TYSL+     E    H Q F I+PQTG ITT   +D ET     LT
Sbjct: 473 VLAHDRDEGLNSALTYSLA-----ETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLT 527

Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610
           V ARDGGVP LS T  V +++ DVNDNEP+F Q  Y  ++ E+  VG  + +V A+D D 
Sbjct: 528 VVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDC 587

Query: 611 GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST 670
           G+N  ++Y +    +    F +  ASG I     LD E  ++++   +A D G    S+T
Sbjct: 588 GVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRG--GLSTT 645

Query: 671 VIVHIKIEDINDSPPVFESDCLTFYISE-----NSPIGTTIGEIRAHDPDEGPNAVVHYS 725
            ++ +++ D+ND+ PVF        + E     +    T I  + A DPD G    V Y 
Sbjct: 646 AMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYR 705

Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN-----DVRV 780
           I  G+++  F ++   G      + +V  D  S R +   ++  ++    N     D  V
Sbjct: 706 IVAGNEAGIFRIDRSTGE-----IFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAVV 760

Query: 781 EILVTDVNDNAPVMKDFQIIFNNY-KDCFPVGP-FGRVPAYDADVTDK--LQYRILSGNN 836
            + + D     P+ +  +  +N Y K+  P G   G V A   DV  +  ++Y I SG+ 
Sbjct: 761 FLSIIDAMQRPPIFEKAR--YNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDP 818

Query: 837 ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886
                +   +G++ ++  L+        + +  T G   +    Q+++ +
Sbjct: 819 DGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYGHTQVNIEV 868



 Score =  309 bits (759), Expect = 6e-82
 Identities = 264/887 (29%), Positives = 391/887 (44%), Gaps = 62/887 (6%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + V D ND++P F          E          L A D D+       Y I  V+    
Sbjct: 109 VTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNI--VSG--- 163

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           N  DA             V  +D     L     LDRE    Y++L++A D  +P    L
Sbjct: 164 NVNDAFRLSSHRER--DGVLYLD-----LQISGFLDRETTPGYSLLIEALDGGTP---PL 213

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
               T+++ I D NDN P F++  Y  +V E+ +V  +  + ++ A+D D   N  + YA
Sbjct: 214 RGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTS--VLQVYASDTDADENGLVEYA 271

Query: 191 I--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
           I     + +  F ID  +G + + K LD+E    + LV+ A+D G      T  + I + 
Sbjct: 272 INRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVT 331

Query: 249 DVNDNAPR----FYTSLFQESVSENVPIGYSIVRVQAYDADEGVN-AELTYTMTDKDYTG 303
           DVNDN P     F +      +SE+   G  + R+  +D D     A +  T+   D  G
Sbjct: 332 DVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGD--G 389

Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
           +  L  T D     V     LDRE  + Y L V ATD G PP  A+ +            
Sbjct: 390 HFAL-TTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNP 448

Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI--TGGNTRGRFSITSQNG 419
             F    Y   + E   PGT V+ + A D DE  ++ L Y +  T       F I  Q  
Sbjct: 449 PEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQT- 507

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477
            GLIT    +D + E    LTV A D G    S TA V + I D N+  P+F+ + Y  S
Sbjct: 508 -GLITTRSHIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVS 566

Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
           V E+ P+G  +L VSA+D D G+NA + Y++           H  +F +   +G I    
Sbjct: 567 VAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFK------HLTEFEVRSASGEICIAG 620

Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
            LD E  S Y   V A D G   LS T  +++ + DVNDN PVF  + Y  ++ E     
Sbjct: 621 ELDFERRSSYEFPVLATDRG--GLSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKAS 678

Query: 598 TSVSQ-----VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652
           +  S      V ATD D G  G++ Y +     E G F ID ++G I   +  D  SV T
Sbjct: 679 SQASSTPIVAVVATDPDYGNFGQVSYRI-VAGNEAGIFRIDRSTGEIFVVRP-DMLSVRT 736

Query: 653 ---HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
              H L   A DGG    ++  +V + I D    PP+FE     +Y+ E+ P GT +G +
Sbjct: 737 QPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSV 796

Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
            A   D    + V YSI  GD    FS+ET  G+    +     LD+E+ + +  L I+A
Sbjct: 797 IAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGN----IRIAKPLDHEA-KSQVLLNIQA 851

Query: 770 --ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTD 825
               PP++   +V I V DVNDNAP  +   +  +  +      P     A+D D   + 
Sbjct: 852 TLGEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSG 911

Query: 826 KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
           ++ Y ++  +   L  ++  +G + LS  L+    +  T+ V+ TDG
Sbjct: 912 QVTYSLVKESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDG 958



 Score =  301 bits (738), Expect = 2e-79
 Identities = 272/974 (27%), Positives = 436/974 (44%), Gaps = 81/974 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            ++V D ND+ PVFE  +Y  +V E  S    ++ + A+D D G NA + Y I     D +
Sbjct: 971  VDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNV 1030

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           V   F I   SG +  RA LDRE   RY + V ATD  +P +   
Sbjct: 1031 -------TNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAH-- 1081

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            + T  I V ++D NDN P+F +  Y   ++E++      V+  + A+D D+G N+AIRY+
Sbjct: 1082 AKTRVI-VRVLDANDNDPKFQKSKYEFRIEENL--RRGSVVGVVTASDLDLGENAAIRYS 1138

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            ++  N+   F +  ++G++S  + LD E    Y LV+ A+D G+P RS    + I++ DV
Sbjct: 1139 LLPINS--SFQVHPVTGEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDV 1196

Query: 251  NDNAPRFYTSLFQ-ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT-DKDYTGNVDLP 308
            NDNAP          SV E  P G  +VRV+A D D G NA +TY++   +D  G+    
Sbjct: 1197 NDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHG--L 1254

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
             +IDP SG + T   LD E ++ Y+L V A+DGG+PPR                   F  
Sbjct: 1255 FSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTS 1314

Query: 369  GQYEVELAEDEPPG------------TPVVTLTATDADEDNRLHY---EITGGNTRGRFS 413
                  + ED   G              VV  +  ++ ED R+ Y    +T       F 
Sbjct: 1315 SSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFD 1374

Query: 414  ITSQNGRGLITVAQPLDFKQERRYVLTVSATD----SGGRSDTAMVQINITDANNYAPVF 469
            I   +G   + VA+ LD + +  + L + A D    +  +S    V+I + D N+ AP +
Sbjct: 1375 IDRHSGN--LVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEW 1432

Query: 470  ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS--NEAVAHHDQQFVIN 527
               P    V E  P+GT +   +ATD+D G N  + Y L       NE+       F ++
Sbjct: 1433 PQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMD 1492

Query: 528  PQTGAITTNKLLDRETMSGYLLTVTARDGG---VPSLSDTTDVEISVVDVNDNEPVF--- 581
              TGA++    LD E +  YLL V A D        L  +  V + ++D ND+ P F   
Sbjct: 1493 SLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSP 1552

Query: 582  -KQQLYTANI-MEDAL-VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638
                  TA++ + DA  +G  V+ + A D D G NG++ YE+      EG F I+  +G+
Sbjct: 1553 NSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEI-TGGNGEGRFRINSQTGI 1611

Query: 639  IRTNKAL-----DRESVATHDLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCL 692
            I   K+L     D E     +L   A D G P P+ S++ +H+ ++  +++PP F     
Sbjct: 1612 IELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVY 1671

Query: 693  TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG---------- 742
               I EN P G+ + ++ A       NA + Y I  G  ++ F ++ ++G          
Sbjct: 1672 RATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITTRGQFDR 1731

Query: 743  SDKAELVTMV---DLDYESPRKKYELVIRAASPPLWN-------DV-RVEILVTDVNDNA 791
              +A  V  V   D + +S      +  + +S  + +       DV  + I V DVNDN+
Sbjct: 1732 ESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNS 1791

Query: 792  PVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSM 849
            P  +       +  +    G    V A D D      L Y I  GN  N   ++ ++G +
Sbjct: 1792 PEFRPGSCYGLSVPENSEPGVIHTVVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGEL 1851

Query: 850  TLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFL 909
            +  P L+       T+++  +D           ++ +  E+   N+   +L+  T     
Sbjct: 1852 SARP-LDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQE 1910

Query: 910  SPLLGFFIDGLAAI 923
               LG  +  ++A+
Sbjct: 1911 DAPLGTSVVQISAV 1924



 Score =  288 bits (706), Expect = 2e-75
 Identities = 266/923 (28%), Positives = 427/923 (46%), Gaps = 97/923 (10%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQ--DIGKNAEVEYTIELVTA 67
            ++ VLD ND+ P F        VRE A+ G  V ++   ++  D+ +N+  E   +L   
Sbjct: 1299 RVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVT 1358

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
             TLNP             ++  F ID  SG L+    LDRE  + + + ++A D  +  +
Sbjct: 1359 YTLNP--------LTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTAS-N 1409

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
            +  SS  T+ + + D NDN P++ +    + V E   V    +I    ATDAD G N  +
Sbjct: 1410 NPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPV--GTIIHNFTATDADTGTNGDL 1467

Query: 188  RYAIIGGNTQMQ---------FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS--PS 236
            +Y +I    Q+          F +DSL+G +SL   LD+E V+ Y L+++A D  S    
Sbjct: 1468 QYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTE 1527

Query: 237  RSNTT-QLLINIRDVNDNAPRFYT---------SLFQESVSENVPIGYSIVRVQAYDADE 286
            R  T+  + + I D ND+AP F +         SLF   +S+   IG  +  + A D D 
Sbjct: 1528 RLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLF---ISDATRIGEVVAHIVAVDEDS 1584

Query: 287  GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL-----DRETQAKYQLLVTATDG 341
            G N +LTY +T     GN +    I+ ++G +     L     D E   ++ L++ A D 
Sbjct: 1585 GDNGQLTYEITG----GNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDH 1640

Query: 342  GDP-PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD--ADEDNR 398
            G P P+ ++                F+   Y   + E+ P G+ V+ +TA      E+  
Sbjct: 1641 GQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENAN 1700

Query: 399  LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL------------------- 439
            L YEI  G     F +  Q  RG+IT     D + +  YVL                   
Sbjct: 1701 LSYEIPAGVANDLFHVDWQ--RGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVR 1758

Query: 440  ------TVSATDSGGRSDTAMVQINITDANNYAPVFE-NAPYTASVFEDAPIGTTVLVVS 492
                  ++  T +G   D A + I + D N+ +P F   + Y  SV E++  G    VV 
Sbjct: 1759 KQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGVIHTVV- 1817

Query: 493  ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552
            A+D D G NA + YS++         +   +F I+  +G ++  + LDRE  S Y L + 
Sbjct: 1818 ASDLDEGPNADLIYSITG-------GNLGNKFSIDSSSGELSA-RPLDREQHSRYTLQIQ 1869

Query: 553  ARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG 611
            A D G P S     ++ I V D NDN P FK   YT ++ EDA +GTSV Q+ A DAD+G
Sbjct: 1870 ASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLG 1929

Query: 612  LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT-PPQSST 670
            +N R+ Y L   +  +  F ID  SG+I T   LDRE  A+++   +A DGG    +S+T
Sbjct: 1930 VNARLVYSL--ANETQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSAT 1987

Query: 671  VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD 730
            V V I + DIND+ P+FE       +      G T+ +++A D D G NA + YS+    
Sbjct: 1988 VPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNA-- 2045

Query: 731  DSNSFSLETRQGSDKAELVTMVDLDYESPRKKY-ELVIR-AASPPLWNDVRVEILVTDVN 788
            ++++ S + R       L     L  ES +  + E+V R   +PP  +   +E+L+ +  
Sbjct: 2046 ENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAP 2105

Query: 789  DNAPVMKDFQIIFN-NYKDCFPVGP-FGRVPAYDAD-VTDKLQYRILSGNNANLILLNET 845
               PV++     +    K+  P G    +V A  +D    K+Q+   +GN   ++ L+  
Sbjct: 2106 QGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDGRRQKVQFSFGAGNEDGILSLDSL 2165

Query: 846  TGSMTLSPQLNTNVPKLATMEVS 868
            +G + ++     +  + +T  +S
Sbjct: 2166 SGEIRVNKPHLLDYDRFSTPSMS 2188



 Score =  287 bits (705), Expect = 2e-75
 Identities = 248/842 (29%), Positives = 384/842 (45%), Gaps = 95/842 (11%)

Query: 8    HQQIN--VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELV 65
            H Q+N  V D ND++P FE      SV E A  G  +    A D+D G + +V Y++   
Sbjct: 861  HTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKE 920

Query: 66   TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125
            +   L                   F ID RSG L+    LD E   R+T++V ATD   P
Sbjct: 921  SGKGL-------------------FAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVP 961

Query: 126  VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
                LS+  TI V++ D NDN P F +  Y+V+V E  S+  N  I ++ A+D D G N+
Sbjct: 962  ---SLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSI--NAQIIQVNASDLDTGNNA 1016

Query: 186  AIRYAII------------GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233
             I Y I+              +    F I   SG + L   LD E    Y+L + A D G
Sbjct: 1017 RITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNG 1076

Query: 234  SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293
            +P+    T++++ + D NDN P+F  S ++  + EN+  G  +  V A D D G NA + 
Sbjct: 1077 TPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIR 1136

Query: 294  YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353
            Y++        ++    + P +G + T   LDRE +  Y L+V A D G P RSA     
Sbjct: 1137 YSLLP------INSSFQVHPVTGEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVR 1190

Query: 354  XXXXXXXXXXXXFM-PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGG---N 407
                           P +  V + E++PPGT VV + A D D  ++  + Y I  G   +
Sbjct: 1191 IHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSD 1250

Query: 408  TRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNY 465
              G FSI   +  G+I     LD ++   Y L V+A+D G   R    M+++ + D N+ 
Sbjct: 1251 GHGLFSIDPTS--GVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDN 1308

Query: 466  APVFENAPYTASVFEDAPIGTTVLVVSATD--SDVGINA--------QITYSLSSEISNE 515
             P F ++     V EDA +G  V  +S  +  +DV  N+        ++TY+L + ++ +
Sbjct: 1309 RPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTL-NPLTKD 1367

Query: 516  AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS--LSDTTDVEISVVD 573
             +   +  F I+  +G +   +LLDRE  S + L + A D    +   S    V+I V D
Sbjct: 1368 LI---EAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVAD 1424

Query: 574  VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL--------DPKDR 625
            VNDN P + Q      + E   VGT +    ATDAD G NG + Y L        + +++
Sbjct: 1425 VNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQ 1484

Query: 626  EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG---TPPQSSTVIVHIKIEDIND 682
                F +D  +G +     LD E+V  + L   A+D     T    ++V V ++I D ND
Sbjct: 1485 AMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDAND 1544

Query: 683  SPPVFES------DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736
              P F S         + +IS+ + IG  +  I A D D G N  + Y I GG+    F 
Sbjct: 1545 HAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFR 1604

Query: 737  LETRQGSDKAELVTMVDLDYESPRK--KYELVIRAAS----PPLWNDVRVEILVTDVNDN 790
            + ++ G    ELV  +    E   K  ++ L+I A       P  + + + ++V   ++N
Sbjct: 1605 INSQTGI--IELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNN 1662

Query: 791  AP 792
             P
Sbjct: 1663 PP 1664



 Score =  254 bits (622), Expect = 3e-65
 Identities = 269/952 (28%), Positives = 433/952 (45%), Gaps = 110/952 (11%)

Query: 10   QINVLDCNDHSP-VFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68
            +I+V D ND++P + + Q+   SVRE    GT V+ ++A D+D G+NA + Y+I      
Sbjct: 1190 RIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSI------ 1243

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
             +   D+             +F ID  SG + TR  LD E+ + Y + V A+D  +P  +
Sbjct: 1244 -VKGRDSDG---------HGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRE 1293

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD--ADVGANSA 186
               +   + V ++D NDN P F+  +    V ED ++    V+  I   +  ADV  NS 
Sbjct: 1294 ---TVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAAL--GHVVGSISPIERPADVVRNSV 1348

Query: 187  --------IRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD--GG 233
                    + Y +        +  F ID  SG++ + + LD E    +RL IRA D    
Sbjct: 1349 EESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTAS 1408

Query: 234  SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293
            +  +S+   + I + DVNDNAP +        VSE  P+G  I    A DAD G N +L 
Sbjct: 1409 NNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQ 1468

Query: 294  YTMT------DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD--PP 345
            Y +       ++     + L   +D  +G +     LD E   +Y L+V A D       
Sbjct: 1469 YRLIRYFPQLNESQEQAMSL-FRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTE 1527

Query: 346  RSATA-TXXXXXXXXXXXXXXFM-PGQY-----EVELAEDEPPGTPVVTLTATDADE-DN 397
            R  T+ T              F+ P         + +++    G  V  + A D D  DN
Sbjct: 1528 RLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDN 1587

Query: 398  -RLHYEITGGNTRGRFSITSQNGR-GLITVAQPL--DFKQERRYVLTVSATDSGG---RS 450
             +L YEITGGN  GRF I SQ G   L+    P   D ++  R+ L + A D G    + 
Sbjct: 1588 GQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKK 1647

Query: 451  DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510
             +  + + +  ++N  P F  A Y A++ E+ P G+ VL V+A       NA ++Y + +
Sbjct: 1648 SSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPA 1707

Query: 511  EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG------------- 557
             ++N+        F ++ Q G ITT    DRE+ + Y+L V  RD               
Sbjct: 1708 GVANDL-------FHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQ 1760

Query: 558  --VPSLSDTTD--------VEISVVDVNDNEPVFKQ-QLYTANIMEDALVGTSVSQVGAT 606
                S+ DT++        + I+V DVNDN P F+    Y  ++ E++  G  +  V A+
Sbjct: 1761 RSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGV-IHTVVAS 1819

Query: 607  DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
            D D G N  + Y +   +     F ID +SG +   + LDRE  + + L+  A D G P 
Sbjct: 1820 DLDEGPNADLIYSITGGNLGN-KFSIDSSSGELSA-RPLDREQHSRYTLQIQASDRGQPK 1877

Query: 667  -QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
             +     + I +ED ND+ P F+    T  + E++P+GT++ +I A D D G NA + YS
Sbjct: 1878 SRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYS 1937

Query: 726  IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN----DVRVE 781
            +   +    F+++ + G     + T+  LD E  +  Y  ++ A     +      V V+
Sbjct: 1938 L-ANETQWQFAIDGQSGL----ITTVGKLDREL-QASYNFMVLATDGGRYEVRSATVPVQ 1991

Query: 782  ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNA-- 837
            I V D+NDN P+ + +  I        P     +V A DAD+    ++ Y + + N+A  
Sbjct: 1992 INVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVS 2051

Query: 838  NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889
                +N +TG+++ S  L +   KL  +EV   D  N  ++ + L   LI E
Sbjct: 2052 AKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGE 2103



 Score =  221 bits (540), Expect = 2e-55
 Identities = 205/689 (29%), Positives = 314/689 (45%), Gaps = 72/689 (10%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ +LD NDH+P F        V   +S G T     +    IG     E    +V  D 
Sbjct: 1536 RLRILDANDHAPHF--------VSPNSSGGKTASLFISDATRIG-----EVVAHIVAVDE 1582

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-----LTRASLDREKVARYTVLVKATDQAS 124
             + ++            +  FRI+ ++G +     L  A+ D EK  R+ +++ A D   
Sbjct: 1583 DSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQ 1642

Query: 125  PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184
            P   +  S+  +H+ +   ++N P+F +  Y  ++ E+  V     + ++ A       N
Sbjct: 1643 PEPKK--SSLNLHLIVQGSHNNPPRFLQAVYRATILEN--VPSGSFVLQVTAKSLHGAEN 1698

Query: 185  SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-------- 236
            + + Y I  G     F +D   G ++     D E   SY L +  +D    S        
Sbjct: 1699 ANLSYEIPAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVR 1758

Query: 237  --RSNTT-------------QLLINIRDVNDNAPRFYT-SLFQESVSENVPIGYSIVRVQ 280
              RS+ +              + I + DVNDN+P F   S +  SV EN   G  I  V 
Sbjct: 1759 KQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGV-IHTVV 1817

Query: 281  AYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD 340
            A D DEG NA+L Y++T     GN+    +ID  SG + ++  LDRE  ++Y L + A+D
Sbjct: 1818 ASDLDEGPNADLIYSITG----GNLGNKFSIDSSSGEL-SARPLDREQHSRYTLQIQASD 1872

Query: 341  GGDP-PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDN 397
             G P  R                   F   +Y   + ED P GT VV ++A DAD   + 
Sbjct: 1873 RGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNA 1932

Query: 398  RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAM 454
            RL Y +    T+ +F+I  Q+  GLIT    LD + +  Y   V ATD G    RS T  
Sbjct: 1933 RLVYSL-ANETQWQFAIDGQS--GLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVP 1989

Query: 455  VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
            VQIN+ D N+  P+FE  PY   V      G T+L V A D+D+G NA+I YSL++E  N
Sbjct: 1990 VQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAE--N 2047

Query: 515  EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
             AV+    +F INP TGA++ ++ L  E+     L V ARD G P  S    +E+ + + 
Sbjct: 2048 SAVS---AKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEA 2104

Query: 575  NDNEPV--FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632
                PV  F+ + Y   + E++  GT + QV A  +D G   ++ +       E+G   +
Sbjct: 2105 PQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSD-GRRQKVQFSFG-AGNEDGILSL 2162

Query: 633  DPASGVIRTNK--ALDRESVATHDLKAVA 659
            D  SG IR NK   LD +  +T  + A++
Sbjct: 2163 DSLSGEIRVNKPHLLDYDRFSTPSMSALS 2191



 Score =  217 bits (531), Expect = 3e-54
 Identities = 208/750 (27%), Positives = 334/750 (44%), Gaps = 83/750 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I + D ND+SP F  +Q+ A+V EG + GT V  + A D D G NA + Y I     D  
Sbjct: 2257 IELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHI----VDG- 2311

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N ++A          ++  F     SG + T   LDRE    Y + + ATD+  P   ++
Sbjct: 2312 NHDNAFV--------IEPAF-----SGIVRTNIVLDREIRDIYKLKIIATDEGVP---QM 2355

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY- 189
            + TATI V I+D NDN P F      V+V E   +    VI  I A D D       R  
Sbjct: 2356 TGTATIRVQIVDVNDNQPTFPPNN-LVTVSEATEL--GAVITSISANDVDTYPALTYRLG 2412

Query: 190  --AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
              + +       F++D  SG + L + LDYE  + Y L + A D    +R   T L + +
Sbjct: 2413 AESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEAR---TVLTVRV 2469

Query: 248  RDVNDNAPRF-------YTSLFQ--ESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMT 297
             D NDNAP F       Y ++      +SE++ + + ++ V A DAD EG N+++ Y + 
Sbjct: 2470 NDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIY-II 2528

Query: 298  DKDYTGNVDLPITIDPRSGWVYTSG---QLDRETQAKYQLLVTATDGGDPPRSATATXXX 354
            +    G      ++ P +G V  +    Q    +   Y + + A D G P   ++     
Sbjct: 2529 EPAQEG-----FSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRV 2583

Query: 355  XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSI 414
                       F+  QY  +++E  P G+ V+ L     D+       I  GN    F +
Sbjct: 2584 QANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQS----LAIIAGNEESAFEL 2639

Query: 415  TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--------RSDTAMVQINITDANNYA 466
                    I + +PLD ++   Y L +  +   G         S    V I I DAN+  
Sbjct: 2640 LQSKA---IVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNF 2696

Query: 467  PVFE-NAPYTASVFEDAPIGTTVLVVSATDSDV--GINAQITYSLSSEISNEAVAHHDQQ 523
            P+F+ +A Y A + E AP+  ++  + A D+D     N+++ Y ++S        + +  
Sbjct: 2697 PIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITS-------GNDEHM 2749

Query: 524  FVINPQTGAITTNKLLDRET-MSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEPVF 581
            F I+  TG +  N  LD ++    Y L + A D      L       + + D NDNEP F
Sbjct: 2750 FTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKF 2809

Query: 582  KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS---FVIDPASGV 638
                Y   + E+  VG+SV +  A+D D G  G+++Y + P   +E S   F +D  SG+
Sbjct: 2810 PLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGL 2869

Query: 639  IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI-- 696
            + +    D E    +D++ +A D G   + ++V V ++IE  ++  P F      F +  
Sbjct: 2870 VTSAFVFDYEQRQRYDMELLASDMG--GKKASVAVRVEIESRDEFTPQFTERTYRFVLPA 2927

Query: 697  SENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
            +   P G  +G++ A D D GP+  V Y +
Sbjct: 2928 AVALPQGYVVGQVTATDSDSGPDGRVVYQL 2957



 Score =  201 bits (490), Expect = 3e-49
 Identities = 178/569 (31%), Positives = 266/569 (46%), Gaps = 67/569 (11%)

Query: 17   NDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAX 76
            +++ P F    Y A++ E   SG+ VL + A      +NA + Y I    A+        
Sbjct: 1660 HNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVAN-------- 1711

Query: 77   XXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD-------QASPV--- 126
                       D+F +D + G + TR   DRE  A Y + V   D        +S V   
Sbjct: 1712 -----------DLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQ 1760

Query: 127  --SDRLSST--------ATIHVNIIDDNDNYPQFSEKT-YTVSVDEDISVTDNPVIAKIK 175
              SD +  T        ATI++ + D NDN P+F   + Y +SV E+   ++  VI  + 
Sbjct: 1761 RSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPEN---SEPGVIHTVV 1817

Query: 176  ATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP 235
            A+D D G N+ + Y+I GGN   +FSIDS SG++S  + LD EQ   Y L I+A D G P
Sbjct: 1818 ASDLDEGPNADLIYSITGGNLGNKFSIDSSSGELS-ARPLDREQHSRYTLQIQASDRGQP 1876

Query: 236  -SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294
             SR     + I + D NDNAPRF  S +  SV E+ P+G S+V++ A DAD GVNA L Y
Sbjct: 1877 KSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVY 1936

Query: 295  TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD-PPRSATATXX 353
            ++ ++           ID +SG + T G+LDRE QA Y  +V ATDGG    RSAT    
Sbjct: 1937 SLANE-----TQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQ 1991

Query: 354  XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGR 411
                        F    Y  ++     PG  ++ + A DAD   +  + Y +   N+   
Sbjct: 1992 INVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVS 2051

Query: 412  FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPV- 468
                     G ++ +Q L  +  +   L V A D G   +S   ++++ I +A    PV 
Sbjct: 2052 AKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVL 2111

Query: 469  -FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527
             F+N  Y   + E++P GT +L V A  SD G   ++ +S  +   NE     D    ++
Sbjct: 2112 RFQNETYRVMLKENSPSGTRLLQVVALRSD-GRRQKVQFSFGA--GNE-----DGILSLD 2163

Query: 528  PQTGAITTNK--LLDRETMSGYLLTVTAR 554
              +G I  NK  LLD +  S   ++  +R
Sbjct: 2164 SLSGEIRVNKPHLLDYDRFSTPSMSALSR 2192



 Score =  198 bits (484), Expect = 1e-48
 Identities = 180/608 (29%), Positives = 282/608 (46%), Gaps = 57/608 (9%)

Query: 215  LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY 274
            L   Q    R+V+ A+   +P  ++  +L+I + D NDN+P+F    F  +VSE    G 
Sbjct: 2227 LTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGT 2286

Query: 275  SIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR-SGWVYTSGQLDRETQAKYQ 333
             + +V A+D+D G NA L Y + D    GN D    I+P  SG V T+  LDRE +  Y+
Sbjct: 2287 FVAQVHAFDSDAGSNARLRYHIVD----GNHDNAFVIEPAFSGIVRTNIVLDREIRDIYK 2342

Query: 334  LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393
            L + ATD G P  + TAT              F P    V ++E    G  + +++A D 
Sbjct: 2343 LKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNL-VTVSEATELGAVITSISANDV 2401

Query: 394  DEDNRLHYEITGGNTRG--RFSITS-QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS 450
            D    L Y +   +T      SI +     G + + + LD++ ++ Y L V A+D+   +
Sbjct: 2402 DTYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEA 2461

Query: 451  DTAMVQINITDANNYAPV---------FENAPYTASVFEDAPIGTTVLVVSATDSD-VGI 500
             T +  + + D N+ APV         F   P  + + E   +   +L V+ATD+D  G 
Sbjct: 2462 RTVLT-VRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGN 2520

Query: 501  NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN--KLLDRETMSG-YLLTVTARDGG 557
            N+++ Y +  E + E        F ++P  G ++ N  +L    + SG Y + + A+D G
Sbjct: 2521 NSKVIYII--EPAQEG-------FSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAG 2571

Query: 558  VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617
             P+L  +T + +   D       F Q  Y A I E A +G+ V Q+G    D  L     
Sbjct: 2572 KPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQSL----- 2626

Query: 618  YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP------QSSTV 671
                    EE +F +  +  ++   K LDRE    + L+ V      PP       SS +
Sbjct: 2627 --AIIAGNEESAFELLQSKAIVLV-KPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGI 2683

Query: 672  IVHIKIEDINDSPPVFE-SDCLTFYISENSPIGTTIGEIRAHDPDE--GPNAVVHYSIKG 728
             V I I D ND+ P+F+ S      ISE +P+  +I +++A D D+   PN+ V Y I  
Sbjct: 2684 SVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITS 2743

Query: 729  GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP----PLWNDVRVEILV 784
            G+D + F+++   G     L     LDY+S  K YEL+IRA       PL +     + +
Sbjct: 2744 GNDEHMFTIDLVTG----VLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLEL 2799

Query: 785  TDVNDNAP 792
             D NDN P
Sbjct: 2800 HDENDNEP 2807



 Score =  196 bits (477), Expect = 1e-47
 Identities = 190/665 (28%), Positives = 301/665 (45%), Gaps = 46/665 (6%)

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            L+S A + + + D+NDN P+FS+K +  +V E  +      +A++ A D+D G+N+ +RY
Sbjct: 2249 LASYAELVIELEDENDNSPKFSQKQFVATVSEGNN--KGTFVAQVHAFDSDAGSNARLRY 2306

Query: 190  AIIGGNTQMQFSID-SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
             I+ GN    F I+ + SG V     LD E    Y+L I A D G P  + T  + + I 
Sbjct: 2307 HIVDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIV 2366

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            DVNDN P F  +    +VSE   +G  I  + A D D      LTY +  +      ++ 
Sbjct: 2367 DVNDNQPTFPPNNLV-TVSEATELGAVITSISANDVD--TYPALTYRLGAESTVDIENMS 2423

Query: 309  I-TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
            I  +D  SG +    +LD E Q +Y+L V A+D     R+                    
Sbjct: 2424 IFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEARTVLTVRVNDENDNAPVFLAQQ 2483

Query: 368  PGQYEV------ELAEDEPPGTPVVTLTATDAD-EDNRLHYEITGGNTRGRFSITSQNGR 420
            P  Y        E++E       ++T+ ATDAD E N           +  FS+   NG 
Sbjct: 2484 PPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNGV 2543

Query: 421  GLITVA--QPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTA 476
              + ++  QP        Y + + A D+G      + ++++   D  +    F    Y A
Sbjct: 2544 VSVNMSRLQPA-VSSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRA 2602

Query: 477  SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
             + E AP+G+ VL        +G +A +  SL+    NE  A     F +  Q+ AI   
Sbjct: 2603 QISEAAPLGSVVL-------QLGQDA-LDQSLAIIAGNEESA-----FELL-QSKAIVLV 2648

Query: 537  KLLDRETMSGYLLT-VTARDGGVPSLSDTTD-----VEISVVDVNDNEPVFKQQL-YTAN 589
            K LDRE    Y L  V +   G P +S         V I+++D NDN P+F +   Y A 
Sbjct: 2649 KPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAE 2708

Query: 590  IMEDALVGTSVSQVGATDADVGL--NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647
            I E A +  S++Q+ A DAD     N  + Y++     +E  F ID  +GV+  N  LD 
Sbjct: 2709 ISELAPLRYSIAQLQAIDADQENTPNSEVVYDIT-SGNDEHMFTIDLVTGVLFVNNRLDY 2767

Query: 648  ESVA-THDLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
            +S A +++L   A D     P  S     +++ D ND+ P F       +++EN P+G++
Sbjct: 2768 DSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSS 2827

Query: 706  IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765
            +    A D D+GP   ++YSI       S     R  S+   + +    DYE  R++Y++
Sbjct: 2828 VFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQ-RQRYDM 2886

Query: 766  VIRAA 770
             + A+
Sbjct: 2887 ELLAS 2891



 Score =  142 bits (345), Expect = 9e-32
 Identities = 177/697 (25%), Positives = 300/697 (43%), Gaps = 61/697 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V D ND++PVF  QQ  A              +     +I ++  V++ +  V A   
Sbjct: 2467 VRVNDENDNAPVFLAQQPPA-----------YFAILPAISEISESLSVDFDLLTVNATDA 2515

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR---YTVLVKATDQASPVS 127
            + E             Q+ F +   +G +    S  +  V+    Y V + A D   P  
Sbjct: 2516 DSEGNNSKVIYIIEPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPA- 2574

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
              L S+  + V   D+     QF +  Y   + E   +    V+ ++     D       
Sbjct: 2575 --LKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPL--GSVVLQLGQDALDQSL---- 2626

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRL-VIRAQDGGSP-----SRSNTT 241
              AII GN +  F +   S  + LVK LD E+   Y+L ++ +   G P     + S+  
Sbjct: 2627 --AIIAGNEESAFELLQ-SKAIVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGI 2683

Query: 242  QLLINIRDVNDNAPRFYTSL-FQESVSENVPIGYSIVRVQAYDADEG--VNAELTYTMTD 298
             ++I I D NDN P F  S  ++  +SE  P+ YSI ++QA DAD+    N+E+ Y +T 
Sbjct: 2684 SVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDIT- 2742

Query: 299  KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDP-PRSATATXXXXX 356
               +GN +   TID  +G ++ + +LD ++ AK Y+L++ A D     P  +        
Sbjct: 2743 ---SGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLEL 2799

Query: 357  XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEI----TGGNTRG 410
                     F   +Y   LAE+EP G+ V    A+D D+    +L+Y I    +  ++  
Sbjct: 2800 HDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWK 2859

Query: 411  RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFE 470
             F + S++G  L+T A   D++Q +RY + + A+D GG+  +  V++ I   + + P F 
Sbjct: 2860 MFRVDSESG--LVTSAFVFDYEQRQRYDMELLASDMGGKKASVAVRVEIESRDEFTPQFT 2917

Query: 471  NAPY--TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528
               Y          P G  V  V+ATDSD G + ++ Y LS+  S+  V       +I  
Sbjct: 2918 ERTYRFVLPAAVALPQGYVVGQVTATDSDSGPDGRVVYQLSAPHSHFKVNRSSGAVLIKR 2977

Query: 529  Q---TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV-NDNEPVFKQQ 584
            +    G    N  +D   +S   L ++A  G   SLS    VEI++  + +    +    
Sbjct: 2978 KLKLDGDGDGNLYMDGRDIS---LVISASSGRHNSLSSMAVVEIALDPLAHPGTNLASAG 3034

Query: 585  LYTANIMEDALVGTSVSQVGATDADVGLNGRIHY-ELDPKDREEGSFVIDPASGVIRTNK 643
              ++  + D  +G  V+ +    A  G+   IH     P++  +     D A GV  TN 
Sbjct: 3035 GSSSGSIGDWAIGLLVAFLLVLCAAAGIFLFIHMRSRKPRNAVKPHLATDNA-GVGNTNS 3093

Query: 644  ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680
             +D  +  T  ++  +I GG    +S      K ++I
Sbjct: 3094 YVDPSAFDTIPIRG-SISGGAAGAASGQFAPPKYDEI 3129



 Score =  132 bits (318), Expect = 2e-28
 Identities = 83/246 (33%), Positives = 125/246 (50%), Gaps = 5/246 (2%)

Query: 549  LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
            + + AR    P L+   ++ I + D NDN P F Q+ + A + E    GT V+QV A D+
Sbjct: 2237 VVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDS 2296

Query: 609  DVGLNGRIHYELDPKDREEGSFVIDPA-SGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
            D G N R+ Y +      + +FVI+PA SG++RTN  LDRE    + LK +A D G P  
Sbjct: 2297 DAGSNARLRYHI-VDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQM 2355

Query: 668  SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
            + T  + ++I D+ND+ P F  + L   +SE + +G  I  I A+D D  P        +
Sbjct: 2356 TGTATIRVQIVDVNDNQPTFPPNNLV-TVSEATELGAVITSISANDVDTYPALTYRLGAE 2414

Query: 728  GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDV 787
               D  + S+         +LV    LDYE  +++YEL + A+         + + V D 
Sbjct: 2415 STVDIENMSIFALD-RYSGKLVLKRRLDYEL-QQEYELDVIASDAAHEARTVLTVRVNDE 2472

Query: 788  NDNAPV 793
            NDNAPV
Sbjct: 2473 NDNAPV 2478



 Score =  116 bits (280), Expect = 7e-24
 Identities = 131/519 (25%), Positives = 228/519 (43%), Gaps = 49/519 (9%)

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLI 423
            F   Q+   ++E    GT V  + A D+D  +  RL Y I  GN    F I      G++
Sbjct: 2269 FSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDNAFVIEPAFS-GIV 2327

Query: 424  TVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
                 LD +    Y L + ATD G    + TA +++ I D N+  P F       +V E 
Sbjct: 2328 RTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFP-PNNLVTVSEA 2386

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
              +G  +  +SA D D      +TY L +E + +    +   F ++  +G +   + LD 
Sbjct: 2387 TELGAVITSISANDVDT--YPALTYRLGAESTVDI--ENMSIFALDRYSGKLVLKRRLDY 2442

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ---LYTA------NIME 592
            E    Y L V A D    +    T + + V D NDN PVF  Q    Y A       I E
Sbjct: 2443 ELQQEYELDVIASDAAHEA---RTVLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISE 2499

Query: 593  DALVGTSVSQVGATDADV-GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA 651
               V   +  V ATDAD  G N ++ Y ++P   +EG F + P++GV+  N +  + +V+
Sbjct: 2500 SLSVDFDLLTVNATDADSEGNNSKVIYIIEPA--QEG-FSVHPSNGVVSVNMSRLQPAVS 2556

Query: 652  T---HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
            +   + ++ +A D G P   S+ ++ ++  D       F  +     ISE +P+G+ + +
Sbjct: 2557 SSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQ 2616

Query: 709  IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768
            +     D+        +I  G++ ++F L     S    LV  +D +     K   ++  
Sbjct: 2617 LGQDALDQS------LAIIAGNEESAFELLQ---SKAIVLVKPLDRERNDLYKLRLVLSH 2667

Query: 769  AASPPLWNDVR----VEILVT--DVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDA 821
               PPL + +     + +++T  D NDN P+            +  P+     ++ A DA
Sbjct: 2668 PHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDA 2727

Query: 822  DVTD----KLQYRILSGNNANLILLNETTGSMTLSPQLN 856
            D  +    ++ Y I SGN+ ++  ++  TG + ++ +L+
Sbjct: 2728 DQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLD 2766



 Score = 74.5 bits (175), Expect = 4e-11
 Identities = 77/297 (25%), Positives = 131/297 (44%), Gaps = 20/297 (6%)

Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
           Q+G      G++    Y +  +   E    ID A+G IRT   LDRE+ A++ L A+ + 
Sbjct: 42  QIGYIGDFGGIDSGPPYIIVAEAGVETDLAIDRATGEIRTKVKLDRETRASYSLVAIPLS 101

Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
           G        + V + ++D ND+ P F    +     EN+P       + A D D  P   
Sbjct: 102 G------RNIRVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNT 155

Query: 722 VHYSIKGGDDSNSFSLET---RQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLW 775
             Y+I  G+ +++F L +   R G    +L     LD E+    Y L+I A    +PPL 
Sbjct: 156 QRYNIVSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRET-TPGYSLLIEALDGGTPPLR 214

Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDK--LQYRI- 831
             + V I + DVNDN P+    +  F    +   VG    +V A D D  +   ++Y I 
Sbjct: 215 GFMTVNITIQDVNDNQPIFNQSR-YFATVPENATVGTSVLQVYASDTDADENGLVEYAIN 273

Query: 832 -LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRL 886
               +   +  ++  TG++ ++  L+    +L  + V   D G   ++    +S+R+
Sbjct: 274 RRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRV 330



 Score = 36.7 bits (81), Expect = 9.2
 Identities = 38/165 (23%), Positives = 74/165 (44%), Gaps = 8/165 (4%)

Query: 730  DDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIRAASPP-LWNDVRVEILVTDV 787
            D+S+         S +A   +   L    P + +  LV R A  P L +   + I + D 
Sbjct: 2203 DESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDE 2262

Query: 788  NDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTD--KLQYRILSGNNANLILLNE 844
            NDN+P     Q +     +    G F  +V A+D+D     +L+Y I+ GN+ N  ++  
Sbjct: 2263 NDNSPKFSQKQFVAT-VSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDNAFVIEP 2321

Query: 845  T-TGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLI 887
              +G +  +  L+  +  +  +++  TD GV ++     + V+++
Sbjct: 2322 AFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIV 2366


>UniRef50_A7RQ19 Cluster: Predicted protein; n=5; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 3766

 Score =  356 bits (875), Expect = 6e-96
 Identities = 408/1561 (26%), Positives = 652/1561 (41%), Gaps = 177/1561 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I + D ND  P F++  Y+A VRE A  GTTV+T+KATD+D G    V Y ++  +    
Sbjct: 1810 ITLEDVNDDKPTFDLGNYDARVRENAPIGTTVITIKATDRDTGDAGVVTYFLKAGS---- 1865

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                             + F ID  SG L T+ S DRE  + ++V+V A D+ +     L
Sbjct: 1866 ----------------DEHFAIDVNSGTLTTKKSFDREGQSLFSVIVIARDKGNNPG-AL 1908

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S    + V ++D+ND+ PQF +  +  SV E  S T    I ++ ATD D+G N+ + Y 
Sbjct: 1909 SEEVAVKVLVVDENDSPPQFDQAEFQTSVSE--SATIGTSILEVVATDQDIGDNAKLEYF 1966

Query: 191  IIGGNTQMQFSIDSLS------GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
            I GG+ +  F++ ++S      G+V +   LD+E   SY + + A DG     S TT++L
Sbjct: 1967 ISGGDGRFWFAVQTISKSGRTYGEVQVDARLDFETKSSYTIDVTATDGRF---SATTRVL 2023

Query: 245  INIRDVNDNAPRFYT--------SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
            I I D ND  P F T         ++   VSE    G  +++V A D D   +  + YT+
Sbjct: 2024 ITITDANDIVPMFMTLTTPTLLSPIYTGRVSEMTGSGVEVLKVYAVDTD---SPNIQYTL 2080

Query: 297  TDKDYTGNVDLPITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATDGGDPPRSATATXXXX 355
                    +          G + T  Q LDRE    +   V A DG     + +A     
Sbjct: 2081 EGSSSYFTIAARQEGGKFVGIISTGSQPLDREATPIFSFNVLAKDG---VHTGSAYIEIN 2137

Query: 356  XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-----DNRLHYEITGGNTRG 410
                      F    Y   + E++  GT V+ + A D D+     +  + Y +T  N  G
Sbjct: 2138 VTDINDNQPRFPNSLYVGYVEENKAAGTSVMYVQAHDDDDPYLGGNAEIRYTLTD-NAGG 2196

Query: 411  RFSITSQNGRGLITVAQPLDFKQE-RRYVLTVSATDSGGR--SDTAMVQINITDANNYAP 467
            +F I +     L+T  + LD +     + +TV ATD G    S T +  I +TDAN++AP
Sbjct: 2197 KFKIDANTA--LVTTEEILDRETSPNSFTITVLATDQGANKLSTTKVATIYVTDANDHAP 2254

Query: 468  VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527
            VF    +  +V ED   G  V  VSATD+D G NA++ + ++    NE  A     F ++
Sbjct: 2255 VFTKRIFRGTVSEDVRPGYVVTSVSATDTDTGPNAELEFVVTH--GNEPAA-----FYVD 2307

Query: 528  PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD--VEISVVDVNDNEPVFKQQL 585
            P  G +  + +L+      Y LTVT  D G+P LSD +   V I++ D NDN P+F    
Sbjct: 2308 PSKGTVHVSGILNYTLRKSYNLTVTVSDRGMPVLSDNSPAYVLITITDANDNAPIFIPNQ 2367

Query: 586  YTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL---DPKDREEGSFVIDPAS-GVIRT 641
            Y   + ED  VG+ V  V A D D G N +  +++   +P D  E     D +S G++RT
Sbjct: 2368 YNKTVAEDLAVGSPVVVVTAVDYDSGDNAKFVFDITGGNPDDLFEVVPNPDNSSLGIVRT 2427

Query: 642  NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701
               LDRE+   H L+  A D G    +    V + + D+ND+ P F+       I EN  
Sbjct: 2428 RLPLDRETTPIHHLEITAKDTGG--LTGKAHVWLTLLDVNDNGPWFQPPFFVGKIKENVN 2485

Query: 702  IGTTIGEIRAHDPDEGPN-AVVHYSIKGGDDSNSFSLETRQGSD-KAELVTMVDLDYESP 759
            +   + ++ A+DPD   N A   Y+I  G  S +F+ +    ++   ++ +    D E+ 
Sbjct: 2486 VKQFVTKVSANDPDTKNNGAPFTYAIYNGTVSGNFAFDIATITNVTTDMSSSGTFDRET- 2544

Query: 760  RKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRV 816
               + + I       P   N   V + V D NDN P      II N+Y   F  GP  + 
Sbjct: 2545 MTTWTIGIAGTDSGRPAKSNFTYVYVDVQDDNDNEPYDGRMTIIVNSYNGKFRGGPIAKT 2604

Query: 817  PAYDADVT-DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG--- 872
               DAD   D   Y + S    N   ++ TTG ++ +  +      L      V  G   
Sbjct: 2605 YYRDADYDGDVNTYTLQSQTGGNFFTVDTTTGEISAAKDIPVGEYSLVISVTEVNTGNPP 2664

Query: 873  -VNEIK------AMMQLSVRLITEEMLLNSITVRLNDM-TAEQFLSPLLGFFIDGLAAII 924
              NE+       +   + VR IT + + NS+ ++++DM   E F+       +  L+ + 
Sbjct: 2665 RANEVNFPKTVTSRATVIVRDITSKAVSNSVALQISDMRKVEYFVGDYHDVVVGELSRMF 2724

Query: 925  PCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRT 984
                  I +FSVQ  + +    L+V F+ +    E         +  P  +   V  +R 
Sbjct: 2725 GVSSSGIEVFSVQ-PSPIKVMALDVQFAVKTGSDE---------YTKPYDVIRVVTDNRE 2774

Query: 985  TLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTC 1044
             L  L  ++V     ++C  E      +C+ V++  +A    + D    +   P +S T 
Sbjct: 2775 RLTNLG-LKVTSIGIDMCALER-ERVGKCINVVETSSAYKIASGD--YGKVPAPASSITL 2830

Query: 1045 QCPEGFTGVNCETILTKA-SCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVC 1103
               +        TI+    +C  +     C +G  C      G   + C     Y    C
Sbjct: 2831 VSMDVVLRDKYVTIIEPGKNCSNENP---CLNGGTCHDTVPAG--WRVCQCPRGYRGPHC 2885

Query: 1104 ELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRY-----NERHDFLAL- 1157
            E   R+F  +S++  P L       L  +F T+   GL+LY G       N   DFL + 
Sbjct: 2886 EQTTRTFRGTSYIWLPKLTAYDIRELSFEFTTEFKDGLMLYQGPLKPGDNNGAKDFLPVF 2945

Query: 1158 ------ELVSSEAGRGGGPGLRFSFSLGG-------GKSEITV----EGNVGDGSWHTVE 1200
                  +   +E         ++    G        G   IT+      N+ D  WHTV+
Sbjct: 2946 PNLSIFQATITETITVPRTSWQYFLDEGHLVVRVSLGYEPITINMTRRPNLNDKEWHTVQ 3005

Query: 1201 I--EYFNR-TITMILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLD 1257
            I  +  +R  I +I+D C     +        K      T +V              +L+
Sbjct: 3006 IIRDVIDRKMIRVIIDRCQSAQIVEENGRVFEKRDTCEITGRVKGRSV---------YLN 3056

Query: 1258 LTGPLQIGGLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRC 1317
              GPLQIGG+    +   +    F GCI +     K  DL + +       GC    +  
Sbjct: 3057 GFGPLQIGGVETDLTFIGITTTGFRGCIRNIIDTEKMYDLRNPIKVVNAPEGCTLAGTCP 3116

Query: 1318 SSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPW-------RFGGDGMLSFNPLL 1370
            ++       E S +    +C C  G+TG+ C D +   +       +F   G+ +   L+
Sbjct: 3117 NNCNDKGYCEPSLMAGKSMCVCDLGYTGRACNDRSEANYYLENSFSQFLLTGIRARRELI 3176

Query: 1371 RPIQLPWLNA------LSIR----TRQRDAFVMS---------IQLKSGLLHYSYN-GET 1410
            +P  +P +N       L ++    T+    F+ S         + +K  +L Y +  G+ 
Sbjct: 3177 QP-PVPLMNEYYTHINLQVKLDPGTKDCVLFLSSNSLGTEFNRLDVKDHMLRYIFRLGDR 3235

Query: 1411 M---YLPMATLSDGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIGG 1467
            M    +P   +SDG +H + +   G    + +DY  +         K+     G I  GG
Sbjct: 3236 MKVLSIPQYNISDGKYHSVMVNREGNYAEMQIDYRAKMAGTTGGVQKLLNMGGGSIFTGG 3295

Query: 1468 L 1468
            L
Sbjct: 3296 L 3296



 Score =  277 bits (679), Expect = 3e-72
 Identities = 231/823 (28%), Positives = 377/823 (45%), Gaps = 48/823 (5%)

Query: 86   VQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145
            + + F ++  +G + T + LD E+++      K   +A   +  L ST ++ + + D ND
Sbjct: 1759 IDEKFSVE-TNGQIKTASQLDYEQLSPGDKTFKLQVRAQEENTNLYSTCSVAITLEDVND 1817

Query: 146  NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205
            + P F    Y   V E+  +     +  IKATD D G    + Y +  G+ +  F+ID  
Sbjct: 1818 DKPTFDLGNYDARVRENAPI--GTTVITIKATDRDTGDAGVVTYFLKAGSDE-HFAIDVN 1874

Query: 206  SGDVSLVKTLDYEQVRSYRLVIRAQD-GGSPSR-SNTTQLLINIRDVNDNAPRFYTSLFQ 263
            SG ++  K+ D E    + +++ A+D G +P   S    + + + D ND+ P+F  + FQ
Sbjct: 1875 SGTLTTKKSFDREGQSLFSVIVIARDKGNNPGALSEEVAVKVLVVDENDSPPQFDQAEFQ 1934

Query: 264  ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY---- 319
             SVSE+  IG SI+ V A D D G NA+L Y ++  D  G     +    +SG  Y    
Sbjct: 1935 TSVSESATIGTSILEVVATDQDIGDNAKLEYFISGGD--GRFWFAVQTISKSGRTYGEVQ 1992

Query: 320  TSGQLDRETQAKYQLLVTATDGGDPPRSA-----TATXXXXXXXXXXXXXXFMPGQYEVE 374
               +LD ET++ Y + VTATDG     +      T                 +   Y   
Sbjct: 1993 VDARLDFETKSSYTIDVTATDGRFSATTRVLITITDANDIVPMFMTLTTPTLLSPIYTGR 2052

Query: 375  LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR--GLI-TVAQPLDF 431
            ++E    G  V+ + A D D  N + Y + G ++    +   + G+  G+I T +QPLD 
Sbjct: 2053 VSEMTGSGVEVLKVYAVDTDSPN-IQYTLEGSSSYFTIAARQEGGKFVGIISTGSQPLDR 2111

Query: 432  KQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491
            +    +   V A D G  + +A ++IN+TD N+  P F N+ Y   V E+   GT+V+ V
Sbjct: 2112 EATPIFSFNVLAKD-GVHTGSAYIEINVTDINDNQPRFPNSLYVGYVEENKAAGTSVMYV 2170

Query: 492  SATDSD---VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM-SGY 547
             A D D   +G NA+I Y+L+     +        F I+  T  +TT ++LDRET  + +
Sbjct: 2171 QAHDDDDPYLGGNAEIRYTLTDNAGGK--------FKIDANTALVTTEEILDRETSPNSF 2222

Query: 548  LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
             +TV A D G   LS T    I V D ND+ PVF ++++   + ED   G  V+ V ATD
Sbjct: 2223 TITVLATDQGANKLSTTKVATIYVTDANDHAPVFTKRIFRGTVSEDVRPGYVVTSVSATD 2282

Query: 608  ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
             D G N  + + +     E  +F +DP+ G +  +  L+     +++L     D G P  
Sbjct: 2283 TDTGPNAELEFVVT-HGNEPAAFYVDPSKGTVHVSGILNYTLRKSYNLTVTVSDRGMPVL 2341

Query: 668  S--STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
            S  S   V I I D ND+ P+F  +     ++E+  +G+ +  + A D D G NA   + 
Sbjct: 2342 SDNSPAYVLITITDANDNAPIFIPNQYNKTVAEDLAVGSPVVVVTAVDYDSGDNAKFVFD 2401

Query: 726  IKGGDDSNSFSLETRQGSDKAELV-TMVDLDYESPRKKYELVIRAASPPLWNDVRVEILV 784
            I GG+  + F +     +    +V T + LD E+    +  +    +  L     V + +
Sbjct: 2402 ITGGNPDDLFEVVPNPDNSSLGIVRTRLPLDRETTPIHHLEITAKDTGGLTGKAHVWLTL 2461

Query: 785  TDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDK---LQYRI----LSGNN 836
             DVNDN P  +         K+   V  F  +V A D D  +      Y I    +SGN 
Sbjct: 2462 LDVNDNGPWFQP-PFFVGKIKENVNVKQFVTKVSANDPDTKNNGAPFTYAIYNGTVSGNF 2520

Query: 837  A-NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKA 878
            A ++  +   T  M+ S   +       T+ ++ TD     K+
Sbjct: 2521 AFDIATITNVTTDMSSSGTFDRETMTTWTIGIAGTDSGRPAKS 2563



 Score =  265 bits (649), Expect = 1e-68
 Identities = 242/814 (29%), Positives = 369/814 (45%), Gaps = 90/814 (11%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ V+D ND  P F+  +++ SV E A+ GT++L + ATDQDIG NA++EY I       
Sbjct: 1915 KVLVVDENDSPPQFDQAEFQTSVSESATIGTSILEVVATDQDIGDNAKLEYFI------- 1967

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                            VQ + +     G +   A LD E  + YT+ V ATD       R
Sbjct: 1968 ------SGGDGRFWFAVQTISKSGRTYGEVQVDARLDFETKSSYTIDVTATD------GR 2015

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKT--------YTVSVDEDISVTDNPV-IAKIKATDAD 180
             S+T  + + I D ND  P F   T        YT  V E   +T + V + K+ A D D
Sbjct: 2016 FSATTRVLITITDANDIVPMFMTLTTPTLLSPIYTGRVSE---MTGSGVEVLKVYAVDTD 2072

Query: 181  VGANSAIRYAIIGGNTQMQFSIDSLSGD-VSLVKT----LDYEQVRSYRLVIRAQDGGSP 235
               +  I+Y + G ++    +     G  V ++ T    LD E    +   + A+DG   
Sbjct: 2073 ---SPNIQYTLEGSSSYFTIAARQEGGKFVGIISTGSQPLDREATPIFSFNVLAKDG--- 2126

Query: 236  SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE---GVNAEL 292
              + +  + IN+ D+NDN PRF  SL+   V EN   G S++ VQA+D D+   G NAE+
Sbjct: 2127 VHTGSAYIEINVTDINDNQPRFPNSLYVGYVEENKAAGTSVMYVQAHDDDDPYLGGNAEI 2186

Query: 293  TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA-KYQLLVTATDGGDPPRSATAT 351
             YT+TD     N      ID  +  V T   LDRET    + + V ATD G    S T  
Sbjct: 2187 RYTLTD-----NAGGKFKIDANTALVTTEEILDRETSPNSFTITVLATDQGANKLSTTKV 2241

Query: 352  XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTR 409
                          F    +   ++ED  PG  V +++ATD D   +  L + +T GN  
Sbjct: 2242 ATIYVTDANDHAPVFTKRIFRGTVSEDVRPGYVVTSVSATDTDTGPNAELEFVVTHGNEP 2301

Query: 410  GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNY 465
              F +     +G + V+  L++   + Y LTV+ +D G      +  A V I ITDAN+ 
Sbjct: 2302 AAFYV--DPSKGTVHVSGILNYTLRKSYNLTVTVSDRGMPVLSDNSPAYVLITITDANDN 2359

Query: 466  APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN---EAVAHHDQ 522
            AP+F    Y  +V ED  +G+ V+VV+A D D G NA+  + ++    +   E V + D 
Sbjct: 2360 APIFIPNQYNKTVAEDLAVGSPVVVVTAVDYDSGDNAKFVFDITGGNPDDLFEVVPNPD- 2418

Query: 523  QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582
                N   G + T   LDRET   + L +TA+D G   L+    V ++++DVNDN P F+
Sbjct: 2419 ----NSSLGIVRTRLPLDRETTPIHHLEITAKDTG--GLTGKAHVWLTLLDVNDNGPWFQ 2472

Query: 583  QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV---- 638
               +   I E+  V   V++V A D D   NG             G+F  D A+      
Sbjct: 2473 PPFFVGKIKENVNVKQFVTKVSANDPDTKNNGAPFTYAIYNGTVSGNFAFDIATITNVTT 2532

Query: 639  -IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697
             + ++   DRE++ T  +     D G P +S+   V++ ++D ND+ P ++        S
Sbjct: 2533 DMSSSGTFDRETMTTWTIGIAGTDSGRPAKSNFTYVYVDVQDDNDNEP-YDGRMTIIVNS 2591

Query: 698  ENSPI-GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756
             N    G  I +    D D   + V  Y+++     N F+++T  G    E+    D+  
Sbjct: 2592 YNGKFRGGPIAKTYYRDADYDGD-VNTYTLQSQTGGNFFTVDTTTG----EISAAKDI-- 2644

Query: 757  ESPRKKYELVI-----RAASPPLWNDVRVEILVT 785
              P  +Y LVI        +PP  N+V     VT
Sbjct: 2645 --PVGEYSLVISVTEVNTGNPPRANEVNFPKTVT 2676



 Score =  256 bits (628), Expect = 5e-66
 Identities = 252/868 (29%), Positives = 391/868 (45%), Gaps = 86/868 (9%)

Query: 11   INVLDCNDHSPVFEMQ---QYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
            INV++ ND+ P+F  +   Q +  V    + G     L A D+DIG     + +IE    
Sbjct: 1590 INVVNINDNEPMFPGETNGQIDRKVAGPFAPGVIATRLTAVDKDIGDRVYYKISIEAENY 1649

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFR--IDGRSGALLTRASLDREKVARYTVLVKATDQASP 125
             T++ E            +   FR  I+ R G L  +       +    V V    +  P
Sbjct: 1650 FTID-ERGQLICKNDLKGIASPFRFTIEARDGGLPQKVHTANVLL----VFVNYRPKQQP 1704

Query: 126  VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
            V   +  T      I       P+  E   ++SV+ D+          +K +    G  S
Sbjct: 1705 VRVIVPETTRAXTVIT----RVPRILE---SLSVNSDV----------LKVSAQAPGGKS 1747

Query: 186  AIRYAIIGGNTQM--QFSIDSLSGDVSLVKTLDYEQV----RSYRLVIRAQDGGSPSRSN 239
             + Y+ +  N  +  +FS+++ +G +     LDYEQ+    ++++L +RAQ+  +   S 
Sbjct: 1748 IV-YSPVKANADIDEKFSVET-NGQIKTASQLDYEQLSPGDKTFKLQVRAQEENTNLYS- 1804

Query: 240  TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
            T  + I + DVND+ P F    +   V EN PIG +++ ++A D D G    +TY +   
Sbjct: 1805 TCSVAITLEDVNDDKPTFDLGNYDARVRENAPIGTTVITIKATDRDTGDAGVVTYFLK-- 1862

Query: 300  DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
                  D    ID  SG + T    DRE Q+ + ++V A D G+ P + +          
Sbjct: 1863 ---AGSDEHFAIDVNSGTLTTKKSFDREGQSLFSVIVIARDKGNNPGALSEEVAVKVLVV 1919

Query: 360  XXXXX--XFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSIT 415
                    F   +++  ++E    GT ++ + ATD D  ++ +L Y I+GG+ R  F++ 
Sbjct: 1920 DENDSPPQFDQAEFQTSVSESATIGTSILEVVATDQDIGDNAKLEYFISGGDGRFWFAVQ 1979

Query: 416  --SQNGR--GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN 471
              S++GR  G + V   LDF+ +  Y + V+ATD G  S T  V I ITDAN+  P+F  
Sbjct: 1980 TISKSGRTYGEVQVDARLDFETKSSYTIDVTATD-GRFSATTRVLITITDANDIVPMFMT 2038

Query: 472  -------AP-YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523
                   +P YT  V E    G  VL V A D+D   N Q T   SS     A      +
Sbjct: 2039 LTTPTLLSPIYTGRVSEMTGSGVEVLKVYAVDTD-SPNIQYTLEGSSSYFTIAARQEGGK 2097

Query: 524  FVINPQTGAITT-NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582
            FV     G I+T ++ LDRE    +   V A+DG     + +  +EI+V D+NDN+P F 
Sbjct: 2098 FV-----GIISTGSQPLDREATPIFSFNVLAKDG---VHTGSAYIEINVTDINDNQPRFP 2149

Query: 583  QQLYTANIMEDALVGTSVSQVGATDAD---VGLNGRIHYELDPKDREEGSFVIDPASGVI 639
              LY   + E+   GTSV  V A D D   +G N  I Y L   D   G F ID  + ++
Sbjct: 2150 NSLYVGYVEENKAAGTSVMYVQAHDDDDPYLGGNAEIRYTLT--DNAGGKFKIDANTALV 2207

Query: 640  RTNKALDRE-SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698
             T + LDRE S  +  +  +A D G    S+T +  I + D ND  PVF        +SE
Sbjct: 2208 TTEEILDRETSPNSFTITVLATDQGANKLSTTKVATIYVTDANDHAPVFTKRIFRGTVSE 2267

Query: 699  NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758
            +   G  +  + A D D GPNA + + +  G++  +F ++  +G+     +    L+Y +
Sbjct: 2268 DVRPGYVVTSVSATDTDTGPNAELEFVVTHGNEPAAFYVDPSKGTVHVSGI----LNY-T 2322

Query: 759  PRKKYELVIRAA--SPPLWND---VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF 813
             RK Y L +  +    P+ +D     V I +TD NDNAP+    Q      +D     P 
Sbjct: 2323 LRKSYNLTVTVSDRGMPVLSDNSPAYVLITITDANDNAPIFIPNQYNKTVAEDLAVGSPV 2382

Query: 814  GRVPAYDADVTD--KLQYRILSGNNANL 839
              V A D D  D  K  + I  GN  +L
Sbjct: 2383 VVVTAVDYDSGDNAKFVFDITGGNPDDL 2410



 Score =  221 bits (541), Expect = 2e-55
 Identities = 213/815 (26%), Positives = 341/815 (41%), Gaps = 59/815 (7%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            F ID +SG   +  S D E   +Y + + A    +P  + ++S++ + + I D+ D  PQ
Sbjct: 722  FGIDSKSGRFSSLQSFDYETADKYRIQISAQSGIAP--NIMTSSSDVAITIKDEKDP-PQ 778

Query: 150  FSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSAIRYAIIGGNTQMQF-SIDSLSG 207
            FS+  Y VSV E  SV    +   I+  D D +          +     + + S+    G
Sbjct: 779  FSQSEYKVSVPEGASVRST-LSRGIRFVDEDTLSTQLECSMEEMTSRIPLDYLSVVQDGG 837

Query: 208  DVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265
            +   V  KTLD      +   ++  D   P    TT++ + + D N   P F  + F  S
Sbjct: 838  ECKFVIEKTLDTFVASKFTFDMKVTDKNFPGMFATTKVEVTVTDTNTYTPVFSRTSFWAS 897

Query: 266  VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY----TGNVDLPITIDPRSGWVYTS 321
              + +P   S++++   D D G   E+TY + D       T   D    +D  SG + ++
Sbjct: 898  KPDTLPTDTSVMQLPIIDKDMGSLGEVTYQLIDPTVSAGETSGYDR-FRVDD-SGMIEST 955

Query: 322  GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381
              L   T   Y+L   A DGG P   AT                F    Y   +AE+ P 
Sbjct: 956  NILTANTL--YKLQAKAKDGGSPALEATVDVFISVYPSSDTPVRFSQNPYSASIAENSPL 1013

Query: 382  GTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441
             T V   TAT +   + + Y + GG      ++ S +  G + + + LD ++ + Y L V
Sbjct: 1014 NTEVFRATATKSGSSSGIAYSLVGGQIENGNTMFSIDSSGRVLLLRQLDRERTKSYKLYV 1073

Query: 442  SATDSGGRSDTAM---VQINITDANNYAPVFENAPYTASVFED--APIGTTVLVVSATDS 496
              T +GG    A      + +TD N+  P+F           D  AP  T +  + A DS
Sbjct: 1074 RGTYTGGSLTLATDVECLVTVTDVNDNTPLFTFDRVNKQFVVDNYAPANTIIATLRAVDS 1133

Query: 497  DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKLLDRETMSGYLLTVTARD 555
            D G NAQ+T S+   + + A       F I+  +  + TT KL    T+  Y +TV A D
Sbjct: 1134 DEGANAQVTMSIQGTVPSNA------PFTIDTPSNVLKTTTKL---STVIDYQITVRATD 1184

Query: 556  GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615
             G P     T V + V+++    PVF Q  YT ++ E+  VG  V  V AT  D   N  
Sbjct: 1185 KGSPPQYSETTVIVKVLNIQ-TPPVFGQAKYTVDVQENTKVGQQVISVKATYGDS--NAL 1241

Query: 616  IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675
            + Y     +  + +F ID +SG I   + LDRE + ++ L+ V +  G     + V+V  
Sbjct: 1242 LQYSFVSGNLGD-AFCID-SSGQITVAQPLDREVLPSYTLR-VRVALGNNEDFTEVVV-- 1296

Query: 676  KIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735
             + DIND  P F      F+ +E+   GT+IG++ A D D G +  + Y      D  S 
Sbjct: 1297 SLTDINDDSPTFTKSVYEFFANEDISSGTSIGKVAATDRDSGSHGQISYRFLYASDIQSM 1356

Query: 736  -SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVM 794
               +  Q +    L +   LDYE      ++ I            V I + D+NDN P  
Sbjct: 1357 DKFDLDQTTGIISLASGKSLDYE------DITI----------AEVRIYLRDINDNDPKF 1400

Query: 795  KDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGNNANLILLNETTGSMTLS 852
                       D   +    +V A D D  +  +++Y I++GN      +    G + ++
Sbjct: 1401 SAASYHAKLSLDAPVLEHVVQVTATDLDTANNGRIRYSIVAGNQEGAFQVLTDNGLIRVA 1460

Query: 853  PQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRL 886
              L T       + +   D G  E K  + + V +
Sbjct: 1461 KSLTTVAASSFLLTLEAADSGDPERKGSVNVQVNV 1495



 Score =  221 bits (539), Expect = 3e-55
 Identities = 203/741 (27%), Positives = 343/741 (46%), Gaps = 56/741 (7%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVL---VKATDQASPVSDRLSSTATIHVNI--IDDN 144
            F ID  SG +  +  L+ +      V+   V ATD+    S  LS++  + + +  +DDN
Sbjct: 408  FAIDSTSGVVTLQTQLEYKGNPAQDVIDLVVTATDRNGQ-SGALSASVNLKIEVLDVDDN 466

Query: 145  DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS 204
            +N P F+ +   ++V ED +V     I ++ ATD+D G++  + Y+II G+    F + +
Sbjct: 467  NNAPVFNPQQLELTVSEDSAV--GRTIRRVSATDSDDGSDGQVVYSIIQGSGLGVFQVQA 524

Query: 205  LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
             +GD+ +   LD E++  Y LVI+A+D  +  +S+   +++ I+DV+D+ P+F   ++  
Sbjct: 525  TTGDLIVAAPLDREKMSFYDLVIKAEDKATFPKSSNLYVMVKIQDVDDHFPQFTQPMYYA 584

Query: 265  SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
               E  P    +  V+  D D G    ++Y++T             I P SG + T+G +
Sbjct: 585  KAPEKSPENTFVTVVKVVDHDLG--ESVSYSITGAS-------SFKIVPTSGLILTTGPI 635

Query: 325  DRETQ-AKYQLLVTATDGG-DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382
            D  T+ + Y+L+VTAT       + AT                F    Y V + E++   
Sbjct: 636  DLTTEPSTYELVVTATSTNYGTTKRATGQVNVEITSKTESPPVFKNTPYAVSVPENQGSI 695

Query: 383  TPVVTLTATDADEDNRLHYEITGGNTRGR-FSITSQNGRGLITVAQPLDFKQERRYVLTV 441
              +V + A D  +   + Y I    +RG  F I S++GR   +  Q  D++   +Y + +
Sbjct: 696  ANLVCVAAIDT-KGQPVIYSI---ESRGEPFGIDSKSGR--FSSLQSFDYETADKYRIQI 749

Query: 442  SATDS---GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV-LVVSATDSD 497
            SA         + ++ V I I D  +  P F  + Y  SV E A + +T+   +   D D
Sbjct: 750  SAQSGIAPNIMTSSSDVAITIKDEKD-PPQFSQSEYKVSVPEGASVRSTLSRGIRFVDED 808

Query: 498  VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG 557
              ++ Q+  S+    S   + +     V +         K LD    S +   +   D  
Sbjct: 809  T-LSTQLECSMEEMTSRIPLDY--LSVVQDGGECKFVIEKTLDTFVASKFTFDMKVTDKN 865

Query: 558  VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617
             P +  TT VE++V D N   PVF +  + A+  +     TSV Q+   D D+G  G + 
Sbjct: 866  FPGMFATTKVEVTVTDTNTYTPVFSRTSFWASKPDTLPTDTSVMQLPIIDKDMGSLGEVT 925

Query: 618  YEL-DPK-DREEGS----FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671
            Y+L DP     E S    F +D  SG+I +   L   ++  + L+A A DGG+P   +TV
Sbjct: 926  YQLIDPTVSAGETSGYDRFRVDD-SGMIESTNILTANTL--YKLQAKAKDGGSPALEATV 982

Query: 672  IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD 731
             V I +   +D+P  F  +  +  I+ENSP+ T +   RA     G ++ + YS+ GG  
Sbjct: 983  DVFISVYPSSDTPVRFSQNPYSASIAENSPLNTEV--FRATATKSGSSSGIAYSLVGGQI 1040

Query: 732  SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR----AASPPLWNDVRVEILVTDV 787
             N  ++ +   S +  L+  +D       K Y+L +R      S  L  DV   + VTDV
Sbjct: 1041 ENGNTMFSIDSSGRVLLLRQLD---RERTKSYKLYVRGTYTGGSLTLATDVECLVTVTDV 1097

Query: 788  NDNAPVMK----DFQIIFNNY 804
            NDN P+      + Q + +NY
Sbjct: 1098 NDNTPLFTFDRVNKQFVVDNY 1118



 Score =  218 bits (532), Expect = 2e-54
 Identities = 193/676 (28%), Positives = 303/676 (44%), Gaps = 40/676 (5%)

Query: 134  ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG 193
            A + + + D NDN P+FS  +Y   +  D  V ++  + ++ ATD D   N  IRY+I+ 
Sbjct: 1384 AEVRIYLRDINDNDPKFSAASYHAKLSLDAPVLEH--VVQVTATDLDTANNGRIRYSIVA 1441

Query: 194  GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDN 253
            GN +  F + + +G + + K+L      S+ L + A D G P R  +  + +N+  + D 
Sbjct: 1442 GNQEGAFQVLTDNGLIRVAKSLTTVAASSFLLTLEAADSGDPERKGSVNVQVNVF-LPDG 1500

Query: 254  APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313
             P+F       + +E +     +   +A  ++      L Y +     +GN +    I+P
Sbjct: 1501 PPKFVLDPVIVNATEGIAANQRVAVAKAATSEA-----LKYEIL----SGNTNDMFAINP 1551

Query: 314  RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF---MPGQ 370
             SG + T+ +LD E    Y + + A D  D  RSA+                F     GQ
Sbjct: 1552 SSGVILTTRELDYEEATGYIMNIIARDTRD--RSASVQVIINVVNINDNEPMFPGETNGQ 1609

Query: 371  YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
             + ++A    PG     LTA D D  +R++Y+I+       F+I     RG +     L 
Sbjct: 1610 IDRKVAGPFAPGVIATRLTAVDKDIGDRVYYKISI-EAENYFTIDE---RGQLICKNDLK 1665

Query: 431  FKQERRYVLTVSATDSGGRSDTAMVQINITDAN---NYAPVFENAPYTASVFEDAPIGTT 487
                  +  T+ A D G         + +   N      PV    P T            
Sbjct: 1666 GIASP-FRFTIEARDGGLPQKVHTANVLLVFVNYRPKQQPVRVIVPETTRAXTVITRVPR 1724

Query: 488  VLVVSATDSDV-GINAQITYSLSSEISN-EAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
            +L   + +SDV  ++AQ     S   S  +A A  D++F +    G I T   LD E +S
Sbjct: 1725 ILESLSVNSDVLKVSAQAPGGKSIVYSPVKANADIDEKFSVETN-GQIKTASQLDYEQLS 1783

Query: 546  G----YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
                 + L V A++    +L  T  V I++ DVND++P F    Y A + E+A +GT+V 
Sbjct: 1784 PGDKTFKLQVRAQEENT-NLYSTCSVAITLEDVNDDKPTFDLGNYDARVRENAPIGTTVI 1842

Query: 602  QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
             + ATD D G  G + Y L  K   +  F ID  SG + T K+ DRE  +   +  +A D
Sbjct: 1843 TIKATDRDTGDAGVVTYFL--KAGSDEHFAIDVNSGTLTTKKSFDREGQSLFSVIVIARD 1900

Query: 662  GGTPPQ--SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
             G  P   S  V V + + D NDSPP F+       +SE++ IGT+I E+ A D D G N
Sbjct: 1901 KGNNPGALSEEVAVKVLVVDENDSPPQFDQAEFQTSVSESATIGTSILEVVATDQDIGDN 1960

Query: 720  AVVHYSIKGGDDSNSFSLET--RQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND 777
            A + Y I GGD    F+++T  + G    E+     LD+E+ +  Y + + A        
Sbjct: 1961 AKLEYFISGGDGRFWFAVQTISKSGRTYGEVQVDARLDFET-KSSYTIDVTATDGRFSAT 2019

Query: 778  VRVEILVTDVNDNAPV 793
             RV I +TD ND  P+
Sbjct: 2020 TRVLITITDANDIVPM 2035



 Score =  211 bits (515), Expect = 2e-52
 Identities = 225/831 (27%), Positives = 370/831 (44%), Gaps = 87/831 (10%)

Query: 88   DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
            D+F I+  SG +LT   LD E+   Y + + A D      DR +S   I +N+++ NDN 
Sbjct: 1545 DMFAINPSSGVILTTRELDYEEATGYIMNIIARD----TRDRSASVQVI-INVVNINDNE 1599

Query: 148  PQFSEKTYTVSVDEDISVTDNP-VIA-KIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205
            P F  +T    +D  ++    P VIA ++ A D D+G     + +I   N    F+ID  
Sbjct: 1600 PMFPGET-NGQIDRKVAGPFAPGVIATRLTAVDKDIGDRVYYKISIEAEN---YFTIDER 1655

Query: 206  SGDVSLVKTLDYEQVRS-YRLVIRAQDGGSPSRSNTTQLLI----------NIRDVNDNA 254
                 L+   D + + S +R  I A+DGG P + +T  +L+           +R +    
Sbjct: 1656 G---QLICKNDLKGIASPFRFTIEARDGGLPQKVHTANVLLVFVNYRPKQQPVRVIVPET 1712

Query: 255  PRFYTSLFQ-ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313
             R  T + +   + E++ +   +++V A  A  G    + Y+    +   ++D   +++ 
Sbjct: 1713 TRAXTVITRVPRILESLSVNSDVLKVSA-QAPGG--KSIVYSPVKAN--ADIDEKFSVE- 1766

Query: 314  RSGWVYTSGQLDRET----QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             +G + T+ QLD E        ++L V A +      S T +              F  G
Sbjct: 1767 TNGQIKTASQLDYEQLSPGDKTFKLQVRAQEENTNLYS-TCSVAITLEDVNDDKPTFDLG 1825

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQ 427
             Y+  + E+ P GT V+T+ ATD D  +   + Y +  G+    F+I   +  G +T  +
Sbjct: 1826 NYDARVRENAPIGTTVITIKATDRDTGDAGVVTYFLKAGSDE-HFAIDVNS--GTLTTKK 1882

Query: 428  PLDFKQERRYVLTVSATDSGGR----SDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
              D + +  + + V A D G      S+   V++ + D N+  P F+ A +  SV E A 
Sbjct: 1883 SFDREGQSLFSVIVIARDKGNNPGALSEEVAVKVLVVDENDSPPQFDQAEFQTSVSESAT 1942

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT-GAITTNKLLDRE 542
            IGT++L V ATD D+G NA++ Y +S        A   Q    + +T G +  +  LD E
Sbjct: 1943 IGTSILEVVATDQDIGDNAKLEYFISGGDGRFWFA--VQTISKSGRTYGEVQVDARLDFE 2000

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK--------QQLYTANIMEDA 594
            T S Y + VTA DG     S TT V I++ D ND  P+F           +YT  + E  
Sbjct: 2001 TKSSYTIDVTATDG---RFSATTRVLITITDANDIVPMFMTLTTPTLLSPIYTGRVSEMT 2057

Query: 595  LVGTSVSQVGATDAD-----VGLNGRIHYELDPKDREEGSFVIDPASGVIRT-NKALDRE 648
              G  V +V A D D       L G   Y      +E G FV     G+I T ++ LDRE
Sbjct: 2058 GSGVEVLKVYAVDTDSPNIQYTLEGSSSYFTIAARQEGGKFV-----GIISTGSQPLDRE 2112

Query: 649  SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
            +        +A DG     + +  + I + DIND+ P F +     Y+ EN   GT++  
Sbjct: 2113 ATPIFSFNVLAKDG---VHTGSAYIEINVTDINDNQPRFPNSLYVGYVEENKAAGTSVMY 2169

Query: 709  IRAHDPDE---GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765
            ++AHD D+   G NA + Y++   +    F ++    ++ A + T   LD E+    + +
Sbjct: 2170 VQAHDDDDPYLGGNAEIRYTLT-DNAGGKFKID----ANTALVTTEEILDRETSPNSFTI 2224

Query: 766  VIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD 822
             + A    +  L       I VTD ND+APV           +D  P      V A D D
Sbjct: 2225 TVLATDQGANKLSTTKVATIYVTDANDHAPVFTKRIFRGTVSEDVRPGYVVTSVSATDTD 2284

Query: 823  V--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
                 +L++ +  GN      ++ + G++ +S  LN  + K   + V+V+D
Sbjct: 2285 TGPNAELEFVVTHGNEPAAFYVDPSKGTVHVSGILNYTLRKSYNLTVTVSD 2335



 Score =  203 bits (496), Expect = 5e-50
 Identities = 198/738 (26%), Positives = 323/738 (43%), Gaps = 61/738 (8%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           QI++ D N++ PVFE  +Y  +V E     T++L ++A D DIG+N  + Y +       
Sbjct: 231 QIDIQDTNNNPPVFEKSEYTVTVGEDTPVMTSILRVRARDADIGRNGGIYYYLR------ 284

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            N +D           ++ +  +D +SG   T     R++            Q +  SD 
Sbjct: 285 -NTQD--FTIDAITGVIRPIRMLDFQSGQQRTLEVTARDR-GSSPKAANVNVQVTIRSDI 340

Query: 130 LSSTATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDADVGA-NSAI 187
                 +  +   D +  P F E  ++T+S+ ED  V  N  I  +KA D D G+ N  +
Sbjct: 341 SGYPPVVVPSSSSDRNRPPVFPEGSSFTLSIREDFPV--NGAIQVVKANDPDAGSTNGQL 398

Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS---YRLVIRAQD--GGSPSRSNTTQ 242
           RY++ G N    F+IDS SG V+L   L+Y+   +     LV+ A D  G S + S +  
Sbjct: 399 RYSLSGNN---NFAIDSTSGVVTLQTQLEYKGNPAQDVIDLVVTATDRNGQSGALSASVN 455

Query: 243 LLINIRDV--NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
           L I + DV  N+NAP F     + +VSE+  +G +I RV A D+D+G + ++ Y++    
Sbjct: 456 LKIEVLDVDDNNNAPVFNPQQLELTVSEDSAVGRTIRRVSATDSDDGSDGQVVYSIIQGS 515

Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
             G   +  T    +G +  +  LDRE  + Y L++ A D    P+S+            
Sbjct: 516 GLGVFQVQAT----TGDLIVAAPLDREKMSFYDLVIKAEDKATFPKSSNLYVMVKIQDVD 571

Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420
                F    Y  +  E  P  T V  +   D D    + Y ITG ++   F I   +  
Sbjct: 572 DHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGESVSYSITGASS---FKIVPTS-- 626

Query: 421 GLITVAQPLDFKQE-RRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTA 476
           GLI    P+D   E   Y L V+AT +     +  T  V + IT      PVF+N PY  
Sbjct: 627 GLILTTGPIDLTTEPSTYELVVTATSTNYGTTKRATGQVNVEITSKTESPPVFKNTPYAV 686

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
           SV E+      ++ V+A D+       + YS+ S           + F I+ ++G  ++ 
Sbjct: 687 SVPENQGSIANLVCVAAIDTK---GQPVIYSIES---------RGEPFGIDSKSGRFSSL 734

Query: 537 KLLDRETMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
           +  D ET   Y + ++A+ G  P+ ++ ++DV I++ D  D  P F Q  Y  ++ E A 
Sbjct: 735 QSFDYETADKYRIQISAQSGIAPNIMTSSSDVAITIKDEKD-PPQFSQSEYKVSVPEGAS 793

Query: 596 VGTSVSQ-VGATDADVGLNGRIHYELDPKDR----EEGSFVIDPASGVIRTNKALDR--E 648
           V +++S+ +   D D  L+ ++   ++        +  S V D         K LD    
Sbjct: 794 VRSTLSRGIRFVDEDT-LSTQLECSMEEMTSRIPLDYLSVVQDGGECKFVIEKTLDTFVA 852

Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
           S  T D+K    D   P   +T  V + + D N   PVF          +  P  T++ +
Sbjct: 853 SKFTFDMKVT--DKNFPGMFATTKVEVTVTDTNTYTPVFSRTSFWASKPDTLPTDTSVMQ 910

Query: 709 IRAHDPDEGPNAVVHYSI 726
           +   D D G    V Y +
Sbjct: 911 LPIIDKDMGSLGEVTYQL 928



 Score =  201 bits (491), Expect = 2e-49
 Identities = 226/886 (25%), Positives = 380/886 (42%), Gaps = 81/886 (9%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            ++  + + D +DH P F    Y A   E +   T V  +K  D D+G++  V Y+I   +
Sbjct: 561  LYVMVKIQDVDDHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGES--VSYSITGAS 618

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLD-REKVARYTVLVKATDQASP 125
            +                      F+I   SG +LT   +D   + + Y ++V AT     
Sbjct: 619  S----------------------FKIVPTSGLILTTGPIDLTTEPSTYELVVTATSTNYG 656

Query: 126  VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
             + R  +T  ++V I    ++ P F    Y VSV E+     N V   + A D       
Sbjct: 657  TTKR--ATGQVNVEITSKTESPPVFKNTPYAVSVPENQGSIANLVC--VAAIDTK---GQ 709

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLL 244
             + Y+I        F IDS SG  S +++ DYE    YR+ I AQ G +P+  ++++ + 
Sbjct: 710  PVIYSIESRGEP--FGIDSKSGRFSSLQSFDYETADKYRIQISAQSGIAPNIMTSSSDVA 767

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
            I I+D  D  P+F  S ++ SV E   +  ++ R   +  ++ ++ +L  +M +      
Sbjct: 768  ITIKDEKD-PPQFSQSEYKVSVPEGASVRSTLSRGIRFVDEDTLSTQLECSMEEMTSRIP 826

Query: 305  VD-LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
            +D L +  D           LD    +K+   +  TD   P   AT              
Sbjct: 827  LDYLSVVQDGGECKFVIEKTLDTFVASKFTFDMKVTDKNFPGMFATTKVEVTVTDTNTYT 886

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYE-----ITGGNTRG--RFSI 414
              F    +     +  P  T V+ L   D D  +   + Y+     ++ G T G  RF +
Sbjct: 887  PVFSRTSFWASKPDTLPTDTSVMQLPIIDKDMGSLGEVTYQLIDPTVSAGETSGYDRFRV 946

Query: 415  TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITD-ANNYAPV-FENA 472
                  G+I     L       Y L   A D G  +  A V + I+   ++  PV F   
Sbjct: 947  DDS---GMIESTNILT--ANTLYKLQAKAKDGGSPALEATVDVFISVYPSSDTPVRFSQN 1001

Query: 473  PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
            PY+AS+ E++P+ T V   +AT S  G ++ I YSL   +  + + + +  F I+  +G 
Sbjct: 1002 PYSASIAENSPLNTEVFRATATKS--GSSSGIAYSL---VGGQ-IENGNTMFSID-SSGR 1054

Query: 533  ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE--ISVVDVNDNEPVFKQQLYTANI 590
            +   + LDRE    Y L V     G  SL+  TDVE  ++V DVNDN P+F         
Sbjct: 1055 VLLLRQLDRERTKSYKLYVRGTYTG-GSLTLATDVECLVTVTDVNDNTPLFTFDRVNKQF 1113

Query: 591  MED--ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648
            + D  A   T ++ + A D+D G N ++   +         F ID  S V++T   L   
Sbjct: 1114 VVDNYAPANTIIATLRAVDSDEGANAQVTMSIQGTVPSNAPFTIDTPSNVLKTTTKLS-- 1171

Query: 649  SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
            +V  + +   A D G+PPQ S   V +K+ +I  +PPVF     T  + EN+ +G  +  
Sbjct: 1172 TVIDYQITVRATDKGSPPQYSETTVIVKVLNIQ-TPPVFGQAKYTVDVQENTKVGQQVIS 1230

Query: 709  IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768
            ++A   D   NA++ YS   G+  ++F +++       ++     LD E     Y L +R
Sbjct: 1231 VKATYGDS--NALLQYSFVSGNLGDAFCIDS-----SGQITVAQPLDREV-LPSYTLRVR 1282

Query: 769  AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--K 826
             A     +   V + +TD+ND++P        F   +D       G+V A D D     +
Sbjct: 1283 VALGNNEDFTEVVVSLTDINDDSPTFTKSVYEFFANEDISSGTSIGKVAATDRDSGSHGQ 1342

Query: 827  LQYRILSGN---NANLILLNETTGSMTLSPQLNTNVPKLATMEVSV 869
            + YR L  +   + +   L++TTG ++L+   + +   +   EV +
Sbjct: 1343 ISYRFLYASDIQSMDKFDLDQTTGIISLASGKSLDYEDITIAEVRI 1388



 Score =  200 bits (488), Expect = 4e-49
 Identities = 232/898 (25%), Positives = 382/898 (42%), Gaps = 93/898 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-LKATDQDIGKNAEVEYTIELVTADT 69
            I + D  D  P F   +Y+ SV EGAS  +T+   ++  D+D   + ++E ++E +T+  
Sbjct: 768  ITIKDEKD-PPQFSQSEYKVSVPEGASVRSTLSRGIRFVDEDT-LSTQLECSMEEMTSRI 825

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
              P D           VQD     G     +   +LD    +++T  +K TD+  P    
Sbjct: 826  --PLD-------YLSVVQD-----GGECKFVIEKTLDTFVASKFTFDMKVTDKNFP---G 868

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            + +T  + V + D N   P FS  ++  S  + +  TD  V+ ++   D D+G+   + Y
Sbjct: 869  MFATTKVEVTVTDTNTYTPVFSRTSFWASKPDTLP-TDTSVM-QLPIIDKDMGSLGEVTY 926

Query: 190  AII-----GGNTQM--QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
             +I      G T    +F +D  SG +     L    +  Y+L  +A+DGGSP+   T  
Sbjct: 927  QLIDPTVSAGETSGYDRFRVDD-SGMIESTNILTANTL--YKLQAKAKDGGSPALEATVD 983

Query: 243  LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
            + I++   +D   RF  + +  S++EN P+   + R  A     G ++ + Y++      
Sbjct: 984  VFISVYPSSDTPVRFSQNPYSASIAENSPLNTEVFRATA--TKSGSSSGIAYSLVGGQIE 1041

Query: 303  GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTAT-DGGDPPRSATATXXXXXXXXXX 361
             N +   +ID  SG V    QLDRE    Y+L V  T  GG    +              
Sbjct: 1042 -NGNTMFSIDS-SGRVLLLRQLDRERTKSYKLYVRGTYTGGSLTLATDVECLVTVTDVND 1099

Query: 362  XXXXFMPGQYEVELAEDE--PPGTPVVTLTATDADEDNRLHYEIT-GGNTRGRFSITSQN 418
                F   +   +   D   P  T + TL A D+DE       ++  G        T   
Sbjct: 1100 NTPLFTFDRVNKQFVVDNYAPANTIIATLRAVDSDEGANAQVTMSIQGTVPSNAPFTIDT 1159

Query: 419  GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDAN-NYAPVFENAPYTAS 477
               ++     L    +  Y +TV ATD G     +   + +   N    PVF  A YT  
Sbjct: 1160 PSNVLKTTTKLSTVID--YQITVRATDKGSPPQYSETTVIVKVLNIQTPPVFGQAKYTVD 1217

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            V E+  +G  V+ V AT  D   NA + YS  S    +A       F I+  +G IT  +
Sbjct: 1218 VQENTKVGQQVISVKATYGDS--NALLQYSFVSGNLGDA-------FCID-SSGQITVAQ 1267

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
             LDRE +  Y L V    G   +  D T+V +S+ D+ND+ P F + +Y     ED   G
Sbjct: 1268 PLDREVLPSYTLRVRVALG---NNEDFTEVVVSLTDINDDSPTFTKSVYEFFANEDISSG 1324

Query: 598  TSVSQVGATDADVGLNGRIHYE-LDPKDREE-GSFVIDPASGVIR--TNKALDRESVATH 653
            TS+ +V ATD D G +G+I Y  L   D +    F +D  +G+I   + K+LD E +   
Sbjct: 1325 TSIGKVAATDRDSGSHGQISYRFLYASDIQSMDKFDLDQTTGIISLASGKSLDYEDITIA 1384

Query: 654  DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713
            +                  V I + DIND+ P F +      +S ++P+   + ++ A D
Sbjct: 1385 E------------------VRIYLRDINDNDPKFSAASYHAKLSLDAPVLEHVVQVTATD 1426

Query: 714  PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK-AELVTMVDLDYESPRKKYELVIRAAS- 771
             D   N  + YSI  G+   +F + T  G  + A+ +T V          + L + AA  
Sbjct: 1427 LDTANNGRIRYSIVAGNQEGAFQVLTDNGLIRVAKSLTTV------AASSFLLTLEAADS 1480

Query: 772  --PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQY 829
              P     V V++ V  + D  P      +I N  +    +    RV    A  ++ L+Y
Sbjct: 1481 GDPERKGSVNVQVNVF-LPDGPPKFVLDPVIVNATEG---IAANQRVAVAKAATSEALKY 1536

Query: 830  RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887
             ILSGN  ++  +N ++G +  + +L+        M +   D   +  A +Q+ + ++
Sbjct: 1537 EILSGNTNDMFAINPSSGVILTTRELDYEEATGYIMNIIARD-TRDRSASVQVIINVV 1593



 Score =  180 bits (438), Expect = 5e-43
 Identities = 217/820 (26%), Positives = 352/820 (42%), Gaps = 86/820 (10%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTL-KATDQDIGKNAEVEYTIELVTAD 68
           +I V D N+  P F    Y   + E A+ GTTV  L K   +D  ++    Y  E+V+ +
Sbjct: 119 RITVTDTNNFQPTFGADFYLGYIAEEAAQGTTVGGLEKCHAEDKDRSGIDRY--EIVSGN 176

Query: 69  TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
               E             Q    +   +    TR   D  + +  T+ V+A D       
Sbjct: 177 ----ERGYFVAETKTVGAQKFLVLKATN----TRIVRDPARPS-ITLTVRANDGGG---- 223

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            L  T  I ++I D N+N P F +  YTV+V ED  V  +  I +++A DAD+G N  I 
Sbjct: 224 -LHGTTRIQIDIQDTNNNPPVFEKSEYTVTVGEDTPVMTS--ILRVRARDADIGRNGGIY 280

Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
           Y +   NTQ  F+ID+++G +  ++ LD++  +   L + A+D GS  ++    + + IR
Sbjct: 281 YYL--RNTQ-DFTIDAITGVIRPIRMLDFQSGQQRTLEVTARDRGSSPKAANVNVQVTIR 337

Query: 249 -DVND-------------NAPRFYT--SLFQESVSENVPIGYSIVRVQAYDADEG-VNAE 291
            D++              N P  +   S F  S+ E+ P+  +I  V+A D D G  N +
Sbjct: 338 SDISGYPPVVVPSSSSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKANDPDAGSTNGQ 397

Query: 292 LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD---RETQAKYQLLVTATD----GGDP 344
           L Y++     +GN +    ID  SG V    QL+      Q    L+VTATD     G  
Sbjct: 398 LRYSL-----SGNNN--FAIDSTSGVVTLQTQLEYKGNPAQDVIDLVVTATDRNGQSGAL 450

Query: 345 PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYE 402
             S                  F P Q E+ ++ED   G  +  ++ATD+D+  D ++ Y 
Sbjct: 451 SASVNLKIEVLDVDDNNNAPVFNPQQLELTVSEDSAVGRTIRRVSATDSDDGSDGQVVYS 510

Query: 403 ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINIT 460
           I  G+  G F + +  G   + VA PLD ++   Y L + A D     +S    V + I 
Sbjct: 511 IIQGSGLGVFQVQATTGD--LIVAAPLDREKMSFYDLVIKAEDKATFPKSSNLYVMVKIQ 568

Query: 461 DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520
           D +++ P F    Y A   E +P  T V VV   D D+G    ++YS++   S       
Sbjct: 569 DVDDHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLG--ESVSYSITGASS------- 619

Query: 521 DQQFVINPQTGAITTNKLLDRET-MSGYLLTVTARDGGVPSLSDTT-DVEISVVDVNDNE 578
              F I P +G I T   +D  T  S Y L VTA      +    T  V + +    ++ 
Sbjct: 620 ---FKIVPTSGLILTTGPIDLTTEPSTYELVVTATSTNYGTTKRATGQVNVEITSKTESP 676

Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638
           PVFK   Y  ++ E+     ++  V A D        + Y ++ +      F ID  SG 
Sbjct: 677 PVFKNTPYAVSVPENQGSIANLVCVAAIDTK---GQPVIYSIESRGE---PFGIDSKSGR 730

Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPP-QSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697
             + ++ D E+   + ++  A  G  P   +S+  V I I+D  D PP F        + 
Sbjct: 731 FSSLQSFDYETADKYRIQISAQSGIAPNIMTSSSDVAITIKDEKD-PPQFSQSEYKVSVP 789

Query: 698 ENSPIGTTIGE-IRAHDPDEGPNAVVHYSIKGGDDSNSFS-LETRQGSDKAELVTMVDLD 755
           E + + +T+   IR  D D   +  +  S++          L   Q   + + V    LD
Sbjct: 790 EGASVRSTLSRGIRFVDEDT-LSTQLECSMEEMTSRIPLDYLSVVQDGGECKFVIEKTLD 848

Query: 756 -YESPRKKYELVIRAAS-PPLWNDVRVEILVTDVNDNAPV 793
            + + +  +++ +   + P ++   +VE+ VTD N   PV
Sbjct: 849 TFVASKFTFDMKVTDKNFPGMFATTKVEVTVTDTNTYTPV 888



 Score =  179 bits (436), Expect = 9e-43
 Identities = 191/677 (28%), Positives = 299/677 (44%), Gaps = 80/677 (11%)

Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISV-TDNPVIAKIKATDADVGANSAIRYAIIG 193
           T+ + + D N+  P F    Y   + E+ +  T    + K  A D D   +   RY I+ 
Sbjct: 117 TLRITVTDTNNFQPTFGADFYLGYIAEEAAQGTTVGGLEKCHAEDKD--RSGIDRYEIVS 174

Query: 194 GNTQMQFSIDSLSGDVS---LVKTLDYEQVR-----SYRLVIRAQDGGSPSRSNTTQLLI 245
           GN +  F  ++ +       ++K  +   VR     S  L +RA DGG      TT++ I
Sbjct: 175 GNERGYFVAETKTVGAQKFLVLKATNTRIVRDPARPSITLTVRANDGGG--LHGTTRIQI 232

Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
           +I+D N+N P F  S +  +V E+ P+  SI+RV+A DAD G N  + Y      Y  N 
Sbjct: 233 DIQDTNNNPPVFEKSEYTVTVGEDTPVMTSILRVRARDADIGRNGGIYY------YLRNT 286

Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX----------- 354
               TID  +G +     LD ++  +  L VTA D G  P++A                 
Sbjct: 287 Q-DFTIDAITGVIRPIRMLDFQSGQQRTLEVTARDRGSSPKAANVNVQVTIRSDISGYPP 345

Query: 355 ----XXXXXXXXXXXFMPG-QYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGG 406
                          F  G  + + + ED P    +  + A D D    + +L Y ++G 
Sbjct: 346 VVVPSSSSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKANDPDAGSTNGQLRYSLSGN 405

Query: 407 NTRGRFSITSQNGRGLITVAQPLDFK---QERRYVLTVSATDSGGRSDTAMVQINI---- 459
           N    F+I S +  G++T+   L++K    +    L V+ATD  G+S      +N+    
Sbjct: 406 N---NFAIDSTS--GVVTLQTQLEYKGNPAQDVIDLVVTATDRNGQSGALSASVNLKIEV 460

Query: 460 --TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517
              D NN APVF       +V ED+ +G T+  VSATDSD G + Q+ YS+   I    +
Sbjct: 461 LDVDDNNNAPVFNPQQLELTVSEDSAVGRTIRRVSATDSDDGSDGQVVYSI---IQGSGL 517

Query: 518 AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577
                 F +   TG +     LDRE MS Y L + A D      S    V + + DV+D+
Sbjct: 518 G----VFQVQATTGDLIVAAPLDREKMSFYDLVIKAEDKATFPKSSNLYVMVKIQDVDDH 573

Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637
            P F Q +Y A   E +   T V+ V   D D+G +  + Y +        SF I P SG
Sbjct: 574 FPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGES--VSYSI----TGASSFKIVPTSG 627

Query: 638 VIRTNKALD-RESVATHDL--KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694
           +I T   +D     +T++L   A + + GT  + +T  V+++I    +SPPVF++     
Sbjct: 628 LILTTGPIDLTTEPSTYELVVTATSTNYGT-TKRATGQVNVEITSKTESPPVFKNTPYAV 686

Query: 695 YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDL 754
            + EN      +  + A D    P   V YSI+   +   F ++++ G       ++   
Sbjct: 687 SVPENQGSIANLVCVAAIDTKGQP---VIYSIESRGE--PFGIDSKSG----RFSSLQSF 737

Query: 755 DYESPRKKYELVIRAAS 771
           DYE+   KY + I A S
Sbjct: 738 DYET-ADKYRIQISAQS 753



 Score =  158 bits (383), Expect = 2e-36
 Identities = 161/612 (26%), Positives = 265/612 (43%), Gaps = 66/612 (10%)

Query: 223 YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR----FYTSLFQESVSENVPIGYSIVR 278
           Y L +  +  G         L I + D N+  P     FY     E  ++   +G  + +
Sbjct: 98  YVLTVLRRQRGMTEGGIAWTLRITVTDTNNFQPTFGADFYLGYIAEEAAQGTTVG-GLEK 156

Query: 279 VQAYDAD-EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE-TQAKYQLLV 336
             A D D  G++     +  ++ Y       +          T+ ++ R+  +    L V
Sbjct: 157 CHAEDKDRSGIDRYEIVSGNERGYFVAETKTVGAQKFLVLKATNTRIVRDPARPSITLTV 216

Query: 337 TATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD-- 394
            A DGG      T                F   +Y V + ED P  T ++ + A DAD  
Sbjct: 217 RANDGGG--LHGTTRIQIDIQDTNNNPPVFEKSEYTVTVGEDTPVMTSILRVRARDADIG 274

Query: 395 EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM 454
            +  ++Y +   NT+  F+I +    G+I   + LDF+  ++  L V+A D G     A 
Sbjct: 275 RNGGIYYYLR--NTQD-FTIDAIT--GVIRPIRMLDFQSGQQRTLEVTARDRGSSPKAAN 329

Query: 455 VQINIT---DANNYAPVF---------------ENAPYTASVFEDAPIGTTVLVVSATDS 496
           V + +T   D + Y PV                E + +T S+ ED P+   + VV A D 
Sbjct: 330 VNVQVTIRSDISGYPPVVVPSSSSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKANDP 389

Query: 497 DVG-INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD-----RETMSGYLLT 550
           D G  N Q+ YSLS           +  F I+  +G +T    L+      + +   ++T
Sbjct: 390 DAGSTNGQLRYSLSG----------NNNFAIDSTSGVVTLQTQLEYKGNPAQDVIDLVVT 439

Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNE--PVFKQQLYTANIMEDALVGTSVSQVGATDA 608
            T R+G   +LS + +++I V+DV+DN   PVF  Q     + ED+ VG ++ +V ATD+
Sbjct: 440 ATDRNGQSGALSASVNLKIEVLDVDDNNNAPVFNPQQLELTVSEDSAVGRTIRRVSATDS 499

Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
           D G +G++ Y +  +    G F +   +G +     LDRE ++ +DL   A D  T P+S
Sbjct: 500 DDGSDGQVVYSI-IQGSGLGVFQVQATTGDLIVAAPLDREKMSFYDLVIKAEDKATFPKS 558

Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
           S + V +KI+D++D  P F          E SP  T +  ++  D D G +  V YSI G
Sbjct: 559 SNLYVMVKIQDVDDHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGES--VSYSITG 616

Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR----VEILV 784
              ++SF +    G     ++T   +D  +    YELV+ A S       R    V + +
Sbjct: 617 ---ASSFKIVPTSGL----ILTTGPIDLTTEPSTYELVVTATSTNYGTTKRATGQVNVEI 669

Query: 785 TDVNDNAPVMKD 796
           T   ++ PV K+
Sbjct: 670 TSKTESPPVFKN 681



 Score =  154 bits (374), Expect = 3e-35
 Identities = 148/515 (28%), Positives = 235/515 (45%), Gaps = 50/515 (9%)

Query: 377 EDEPPGTPVVTLTATDADEDNRLHYEI-TGGNTRGRFSITSQNGRGLITVAQPLDFK--Q 433
           E+EP G  V +  +  ++E       + T   +  R    S++G  ++    PL +   +
Sbjct: 37  ENEPEGFRVFSFPSPPSNEIYSFFRALDTASQSALRLFDISEDG--VVVTKNPLVYTDGE 94

Query: 434 ERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491
           E  YVLTV     G         ++I +TD NN+ P F    Y   + E+A  GTTV  +
Sbjct: 95  ENLYVLTVLRRQRGMTEGGIAWTLRITVTDTNNFQPTFGADFYLGYIAEEAAQGTTVGGL 154

Query: 492 SATDSDVGINAQIT-YSLSSEISNEAVAHHDQQFVINPQTGAI---TTNKLLDRETMSGY 547
               ++    + I  Y + S   NE      +   +  Q   +   T  +++        
Sbjct: 155 EKCHAEDKDRSGIDRYEIVS--GNERGYFVAETKTVGAQKFLVLKATNTRIVRDPARPSI 212

Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
            LTV A DGG   L  TT ++I + D N+N PVF++  YT  + ED  V TS+ +V A D
Sbjct: 213 TLTVRANDGG--GLHGTTRIQIDIQDTNNNPPVFEKSEYTVTVGEDTPVMTSILRVRARD 270

Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
           AD+G NG I+Y L    R    F ID  +GVIR  + LD +S     L+  A D G+ P+
Sbjct: 271 ADIGRNGGIYYYL----RNTQDFTIDAITGVIRPIRMLDFQSGQQRTLEVTARDRGSSPK 326

Query: 668 SSTVIVHIKIE-DIN--------------DSPPVF-ESDCLTFYISENSPIGTTIGEIRA 711
           ++ V V + I  DI+              + PPVF E    T  I E+ P+   I  ++A
Sbjct: 327 AANVNVQVTIRSDISGYPPVVVPSSSSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKA 386

Query: 712 HDPDEGP-NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770
           +DPD G  N  + YS+ G   +N+F++++  G     L T ++      +   +LV+ A 
Sbjct: 387 NDPDAGSTNGQLRYSLSG---NNNFAIDSTSGV--VTLQTQLEYKGNPAQDVIDLVVTAT 441

Query: 771 -----SPPLWNDV--RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD- 822
                S  L   V  ++E+L  D N+NAPV    Q+     +D        RV A D+D 
Sbjct: 442 DRNGQSGALSASVNLKIEVLDVDDNNNAPVFNPQQLELTVSEDSAVGRTIRRVSATDSDD 501

Query: 823 -VTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
               ++ Y I+ G+   +  +  TTG + ++  L+
Sbjct: 502 GSDGQVVYSIIQGSGLGVFQVQATTGDLIVAAPLD 536


>UniRef50_UPI000065D51F Cluster: Homolog of Homo sapiens "Fat-like
           cadherin FATJ protein; n=1; Takifugu rubripes|Rep:
           Homolog of Homo sapiens "Fat-like cadherin FATJ protein
           - Takifugu rubripes
          Length = 2263

 Score =  355 bits (872), Expect = 1e-95
 Identities = 275/857 (32%), Positives = 420/857 (49%), Gaps = 71/857 (8%)

Query: 12  NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71
           NVLD ND+ PVF    + A + E    GT  L+L  +D+D G N +V+ +++        
Sbjct: 62  NVLDVNDNPPVFSRGTFSAFLLEDTRVGTCFLSLNVSDKDSGDNGDVKLSVD-------- 113

Query: 72  PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131
            ED              VF I+  S +L  +A LDRE    Y V V A+D+  P + +L+
Sbjct: 114 GEDE-----------DQVFFINP-SSSLCLKAELDREMQNFYNVTVTASDRVQPPALQLT 161

Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191
           STA ++V + D NDN P+F     TV + ED ++  + VI  I+  D D G+N+ + Y  
Sbjct: 162 STARVYVTVGDVNDNAPRFVSAN-TVKITEDAAL--HSVIMTIRTEDDDDGSNALVLY-Y 217

Query: 192 IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251
           +    +  FSIDS SG++ L++ L+ E   S  L + A D GSP  + ++ L + I DVN
Sbjct: 218 LNTTAEGTFSIDSSSGEIHLMEMLNRELHDSLILTVTAIDEGSPRMTTSSSLTVLIEDVN 277

Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311
           ++ P F T L++ +V E+V  G S+++V A D D G+N E+ Y M DK        P ++
Sbjct: 278 NHDPEFSTDLYKVAVREDVRGGTSLLQVSALDRDIGMNGEVRY-MLDK------ARPFSV 330

Query: 312 DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371
           D   G V    +LDRE+ A+Y L +TA D G+PPRS TA               F P   
Sbjct: 331 DAVRGVVMVMERLDRESDAEYTLTLTAVDLGEPPRSTTAVINITVMDINDFVPSFNPELL 390

Query: 372 EVELAEDEPPGTPVV-TLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
            + + E+E   + +   ++A D D   +++L Y I  GN  G FSIT     G   +   
Sbjct: 391 TLHVMENEEDFSKLTYQVSALDEDFGANSQLQYFILSGN-NGHFSITL---NGTFQILHS 446

Query: 429 LDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
           LD + +  +V+T+ A DSG    + T  +QI + D N+  P F    Y   V ED+P GT
Sbjct: 447 LDREVQAVHVVTIIAIDSGSHPLTGTQTLQIIVGDINDNRPAFTGEAYNTIVSEDSPAGT 506

Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
              +V+A+D D G+N +++Y L         A  D  F I+  +G + T  LLDRET++ 
Sbjct: 507 VFAMVTASDIDEGVNGELSYRL---------AGLDMPFAIDETSGELFTTDLLDRETVAI 557

Query: 547 YLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
           Y L V   D  +   LS +  V + + DVND+ P F    Y A +    + G+ V  VGA
Sbjct: 558 YRLVVIGSDKHLTWPLSSSVIVTVLIGDVNDHWPQFMNGPYVAYVPTGMVAGSVVCAVGA 617

Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD-RESVATHDLKAVAIDGGT 664
            D D+ LN  +HY L         F IDP SG + T   L   E +    L     D G 
Sbjct: 618 VDEDIDLNAELHYSL--YGHGSDLFSIDPRSGNVYTTGVLQWAEDLV---LNVHVEDAGE 672

Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
            P+S T  + I+ ++I + P +   + L   I EN P+GT +  + A      P   V +
Sbjct: 673 TPKSDTSTISIRFQNIAEFPQI-SVEILNGSIPENVPVGTLVAVVSAASTRAEP---VSF 728

Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVE 781
            +  G+  N F ++   G+    L     LDYE  +K + L++ A   ASPP  +   + 
Sbjct: 729 YLASGNLDNKFHVDQVSGA----LTVDNPLDYED-KKGFALLMEARDSASPPFSSFEEIH 783

Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNNANL 839
           I ++D+NDN P     +     +++  P      V A DAD  +   + Y I+ GN  N 
Sbjct: 784 ISISDINDNYPQFTQAEYRCEVFEN-HPPSWICDVLAVDADFDNMSLVLYNIIDGNVNNY 842

Query: 840 ILLNETTGSMTLSPQLN 856
            +L+   G ++ +  L+
Sbjct: 843 FMLDHENGLLSTTAALD 859



 Score =  327 bits (803), Expect = 3e-87
 Identities = 302/1109 (27%), Positives = 482/1109 (43%), Gaps = 94/1109 (8%)

Query: 13   VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72
            V D ND+SP+F    Y A + E       V+ L ATD D+G+N+++ Y I     D  N 
Sbjct: 991  VTDANDNSPLFSHSVYSAVLSETKDKDVFVVQLVATDADLGQNSQIFYVI-----DPSNE 1045

Query: 73   EDAXXXXXXXXXXVQDVFRIDGRSGALLTRA--SLDREKVARYTVLVKATDQASPVSDRL 130
            E                F ++  SG + ++   +L       Y   V A D        L
Sbjct: 1046 E----------------FWVNSPSGEIFSKKPLTLPNSSFELYQFTVFAFDCGDAP---L 1086

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG-ANSAIRY 189
             S  T+ V +   N + P F      +     ++V     + K  A D D+  ++SAI+Y
Sbjct: 1087 RSNTTVTVRLEPINFHPPSFLPHRRLIPTPYHMAVGTE--VVKFTAIDQDINNSSSAIKY 1144

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             +IGGN    F +   SG V L ++++      + L ++A D G P  S+  ++   I  
Sbjct: 1145 ILIGGNASSFFWLQEESGKVILEQSVEGSINSFFTLSLQAVDQGYPPLSSLIEVTFEITG 1204

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
             N   P F       SV E++ +G  I R+ A D D G N  ++Y  T +    N D P+
Sbjct: 1205 RNQFPPVFREPDVTFSVPEDLVVGSPIGRIHAEDRDYGTNGAISYGFTHE----NQDSPL 1260

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            ++   SG +    +LD ET   Y L + A DG    +S+                 F+  
Sbjct: 1261 SVGEHSGILTLIKELDFETDRIYHLQMEAKDGAWFTKSSPLNVTVIVLDVNDNPPVFLSS 1320

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
             Y + + E+   GT ++ + A DAD  +  ++ Y +  G    +F+I    G G IT + 
Sbjct: 1321 SYTISVPENSEIGTSILDVKADDADSSSNAQMLYSLFSGRM-DKFAIDP--GSGTITTSD 1377

Query: 428  PLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
              D++QER + +TV A ++G       A V I ITD N + P F+   Y   VF +A IG
Sbjct: 1378 IFDYEQERVFEVTVRAMNAGAHPLFSVARVVIQITDVNEFTPTFDKNQYHFIVFRNARIG 1437

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
            T V  V+ATD D G   Q+ Y++  +   +        F I+  +G I T+ +L  +  S
Sbjct: 1438 TRVGRVTATDGDSGPAGQVFYTMFGQSKTKG-------FEIDNISGEIYTSGILREQADS 1490

Query: 546  GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
              LL V AR+ GV +  D  +  + +     N PVF   +Y+ANI ED+  G+SV  VG 
Sbjct: 1491 RILLKVLARNLGVVTGVDVDETSVHISVTEFNAPVFTSSIYSANITEDSRAGSSVITVGV 1550

Query: 606  TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
             D D   + R+ + ++     + +FV+DP+SGVI  N  LDRE ++ ++L   A   G+P
Sbjct: 1551 LDQD---SSRVIFSIE-NGNTDLAFVVDPSSGVISVNSELDRELLSFYNLTLKAAPSGSP 1606

Query: 666  PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA--VVH 723
              + T  V + + D+ND+PP  +       + EN P GT + ++ A DPD  PN     +
Sbjct: 1607 LDAETANVIVTVVDVNDNPP--QLLYTEVQVRENQPQGTIVAKLTALDPDLPPNQGPFAY 1664

Query: 724  YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI--RAASPPLWNDVRVE 781
            + +    D   FSL T  G    EL T   LD E       LV+   A  P L +   + 
Sbjct: 1665 WLVNPPTD---FSL-TPDG----ELSTTRALDREDTSAYQVLVVVRDAGMPQLSSTAMLY 1716

Query: 782  ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLIL 841
            I + D NDN  + ++  I    +   FP G  G V   D D +D     I SG   N+  
Sbjct: 1717 IRIVDENDNPSLPRNITIEVKYFGASFPGGMIGNVHPEDPDDSDTFSCLIKSG-PLNMFT 1775

Query: 842  LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN-EIKAMMQLSVRLITEEMLLNSITVRL 900
                T  +  SP    +      + V VTD ++  +   + ++ +  T   + + I   +
Sbjct: 1776 TANDTCELWSSP---FHGEATFNLTVEVTDRLHLPVNNSVYVNYKGFTNASVNSCIFFYV 1832

Query: 901  NDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQD-DTDVTGNILNVSFSARRPDAE 959
            +  + E+FLS     F+  L ++        ++F ++   +++       +++ +    E
Sbjct: 1833 SSSSREEFLSYKYLRFVKALDSLFNLQASKTHVFGIKHLGSEILLLAAAKNYNGQYLSRE 1892

Query: 960  VGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKF 1019
            V V+   +              HR  L   + V +     + C+  PC N   C   L  
Sbjct: 1893 VAVSVSAA--------------HRKLLETQSNVTISQISGDSCLMGPCQNGAMCSQNLSV 1938

Query: 1020 GNASGFVNSDSVLFRPIYPVTS-FTCQCPEGFTGVNCETILTKASCEVDGDGSICRS--- 1075
            G+    + S  V+F  + P T  F+C CP  FTG  CE  + +      G+   C +   
Sbjct: 1939 GHTFAVLESKLVIF--VSPQTEVFSCSCPAAFTGALCEGDVDECDVNPCGNEGTCVNTVG 1996

Query: 1076 GSQCVARREGGILCQGCSIDAAYTTAVCE 1104
            G  C     GG     CS D   T  +C+
Sbjct: 1997 GFSCEC--HGGFSGSVCSTDGC-TDLICQ 2022



 Score =  310 bits (761), Expect = 4e-82
 Identities = 251/873 (28%), Positives = 394/873 (45%), Gaps = 66/873 (7%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            QI V D ND+ P F  + Y   V E + +GT    + A+D D G N E+ Y +       
Sbjct: 476  QIIVGDINDNRPAFTGEAYNTIVSEDSPAGTVFAMVTASDIDEGVNGELSYRL------- 528

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                            +   F ID  SG L T   LDRE VA Y ++V  +D+   ++  
Sbjct: 529  --------------AGLDMPFAIDETSGELFTTDLLDRETVAIYRLVVIGSDK--HLTWP 572

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            LSS+  + V I D ND++PQF    Y   V     +    V+  + A D D+  N+ + Y
Sbjct: 573  LSSSVIVTVLIGDVNDHWPQFMNGPYVAYV--PTGMVAGSVVCAVGAVDEDIDLNAELHY 630

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            ++ G  + + FSID  SG+V     L + +     L +  +D G   +S+T+ + I  ++
Sbjct: 631  SLYGHGSDL-FSIDPRSGNVYTTGVLQWAE--DLVLNVHVEDAGETPKSDTSTISIRFQN 687

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA-DEGVNAELTYTMTDKDYTGNVDLP 308
            + +  P+    +   S+ ENVP+G  +  V A     E V+  L         +GN+D  
Sbjct: 688  IAE-FPQISVEILNGSIPENVPVGTLVAVVSAASTRAEPVSFYLA--------SGNLDNK 738

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
              +D  SG +     LD E +  + LL+ A D   PP S+                 F  
Sbjct: 739  FHVDQVSGALTVDNPLDYEDKKGFALLMEARDSASPPFSSFEEIHISISDINDNYPQFTQ 798

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVA 426
             +Y  E+ E+ PP   +  + A DAD DN   + Y I  GN    F +  +N  GL++  
Sbjct: 799  AEYRCEVFENHPPSW-ICDVLAVDADFDNMSLVLYNIIDGNVNNYFMLDHEN--GLLSTT 855

Query: 427  QPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
              LD +    + LT+ A +    S  D A V +++ D N+ AP F    ++  V ED+P+
Sbjct: 856  AALDREDISTFNLTIEAAELNNPSHRDRATVIVSVLDRNDNAPRFSQI-FSIEVPEDSPV 914

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            G + + +S+ D D+G NA I Y +  ++SN         F IN  TG IT  + LDRET 
Sbjct: 915  GHSAIQISSFDDDLGTNAVINYFIIDQLSN-------VPFTINFITGFITVKRPLDRETR 967

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
              Y+L V+A D    + S + DV + V D NDN P+F   +Y+A + E       V Q+ 
Sbjct: 968  DQYILKVSANDS---AWSVSMDVTVVVTDANDNSPLFSHSVYSAVLSETKDKDVFVVQLV 1024

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK--ALDRESVATHDLKAVAIDG 662
            ATDAD+G N +I Y +DP + E   F ++  SG I + K   L   S   +     A D 
Sbjct: 1025 ATDADLGQNSQIFYVIDPSNEE---FWVNSPSGEIFSKKPLTLPNSSFELYQFTVFAFDC 1081

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAV 721
            G  P  S   V +++E IN  PP F           +  +GT + +  A D D    ++ 
Sbjct: 1082 GDAPLRSNTTVTVRLEPINFHPPSFLPHRRLIPTPYHMAVGTEVVKFTAIDQDINNSSSA 1141

Query: 722  VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781
            + Y + GG+ S+ F L+   G  K  L   V+    S        +    PPL + + V 
Sbjct: 1142 IKYILIGGNASSFFWLQEESG--KVILEQSVEGSINSFFTLSLQAVDQGYPPLSSLIEVT 1199

Query: 782  ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANL 839
              +T  N   PV ++  + F+  +D     P GR+ A D D      + Y     N  + 
Sbjct: 1200 FEITGRNQFPPVFREPDVTFSVPEDLVVGSPIGRIHAEDRDYGTNGAISYGFTHENQDSP 1259

Query: 840  ILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            + + E +G +TL  +L+    ++  +++   DG
Sbjct: 1260 LSVGEHSGILTLIKELDFETDRIYHLQMEAKDG 1292



 Score =  301 bits (738), Expect = 2e-79
 Identities = 234/789 (29%), Positives = 374/789 (47%), Gaps = 42/789 (5%)

Query: 43   LTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR 102
            ++++  +  I +N  V   + +V+A +   E            + + F +D  SGAL   
Sbjct: 694  ISVEILNGSIPENVPVGTLVAVVSAASTRAEPVSFYLASGN--LDNKFHVDQVSGALTVD 751

Query: 103  ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162
              LD E    + +L++A D ASP     SS   IH++I D NDNYPQF++  Y   V E+
Sbjct: 752  NPLDYEDKKGFALLMEARDSASPP---FSSFEEIHISISDINDNYPQFTQAEYRCEVFEN 808

Query: 163  ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222
               +    I  + A DAD    S + Y II GN    F +D  +G +S    LD E + +
Sbjct: 809  HPPS---WICDVLAVDADFDNMSLVLYNIIDGNVNNYFMLDHENGLLSTTAALDREDIST 865

Query: 223  YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY 282
            + L I A +  +PS  +   +++++ D NDNAPRF + +F   V E+ P+G+S +++ ++
Sbjct: 866  FNLTIEAAELNNPSHRDRATVIVSVLDRNDNAPRF-SQIFSIEVPEDSPVGHSAIQISSF 924

Query: 283  DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG 342
            D D G NA + Y + D+    NV  P TI+  +G++     LDRET+ +Y L V+A D  
Sbjct: 925  DDDLGTNAVINYFIIDQ--LSNV--PFTINFITGFITVKRPLDRETRDQYILKVSANDSA 980

Query: 343  DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLH 400
                S +                F    Y   L+E +     VV L ATDAD  +++++ 
Sbjct: 981  ---WSVSMDVTVVVTDANDNSPLFSHSVYSAVLSETKDKDVFVVQLVATDADLGQNSQIF 1037

Query: 401  YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQI 457
            Y I   N    F + S +G         L       Y  TV A D G    RS+T  V +
Sbjct: 1038 YVIDPSNE--EFWVNSPSGEIFSKKPLTLPNSSFELYQFTVFAFDCGDAPLRSNTT-VTV 1094

Query: 458  NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV-GINAQITYSLSSEISNEA 516
             +   N + P F              +GT V+  +A D D+   ++ I Y L   I   A
Sbjct: 1095 RLEPINFHPPSFLPHRRLIPTPYHMAVGTEVVKFTAIDQDINNSSSAIKYIL---IGGNA 1151

Query: 517  VAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVND 576
             +     F +  ++G +   + ++    S + L++ A D G P LS   +V   +   N 
Sbjct: 1152 SSF----FWLQEESGKVILEQSVEGSINSFFTLSLQAVDQGYPPLSSLIEVTFEITGRNQ 1207

Query: 577  NEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS 636
              PVF++   T ++ ED +VG+ + ++ A D D G NG I Y     + ++    +   S
Sbjct: 1208 FPPVFREPDVTFSVPEDLVVGSPIGRIHAEDRDYGTNGAISYGF-THENQDSPLSVGEHS 1266

Query: 637  GVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696
            G++   K LD E+   + L+  A DG    +SS + V + + D+ND+PPVF S   T  +
Sbjct: 1267 GILTLIKELDFETDRIYHLQMEAKDGAWFTKSSPLNVTVIVLDVNDNPPVFLSSSYTISV 1326

Query: 697  SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756
             ENS IGT+I +++A D D   NA + YS+  G   + F+++   G+    + T    DY
Sbjct: 1327 PENSEIGTSILDVKADDADSSSNAQMLYSLFSG-RMDKFAIDPGSGT----ITTSDIFDY 1381

Query: 757  ESPRKKYELVIR---AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF 813
            E  R  +E+ +R   A + PL++  RV I +TDVN+  P     Q  F  +++       
Sbjct: 1382 EQER-VFEVTVRAMNAGAHPLFSVARVVIQITDVNEFTPTFDKNQYHFIVFRNARIGTRV 1440

Query: 814  GRVPAYDAD 822
            GRV A D D
Sbjct: 1441 GRVTATDGD 1449



 Score =  293 bits (720), Expect = 3e-77
 Identities = 235/864 (27%), Positives = 398/864 (46%), Gaps = 58/864 (6%)

Query: 2    SVPFCIHQQINVL--DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVE 59
            S PF   ++I++   D ND+ P F   +Y   V E     + +  + A D D    + V 
Sbjct: 773  SPPFSSFEEIHISISDINDNYPQFTQAEYRCEVFENHPP-SWICDVLAVDADFDNMSLVL 831

Query: 60   YTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKA 119
            Y I                       V + F +D  +G L T A+LDRE ++ + + ++A
Sbjct: 832  YNI-------------------IDGNVNNYFMLDHENGLLSTTAALDREDISTFNLTIEA 872

Query: 120  TDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA 179
             +  +P S R    AT+ V+++D NDN P+FS+  +++ V ED  V  + +  +I + D 
Sbjct: 873  AELNNP-SHR--DRATVIVSVLDRNDNAPRFSQ-IFSIEVPEDSPVGHSAI--QISSFDD 926

Query: 180  DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239
            D+G N+ I Y II   + + F+I+ ++G +++ + LD E    Y L + A D    + S 
Sbjct: 927  DLGTNAVINYFIIDQLSNVPFTINFITGFITVKRPLDRETRDQYILKVSANDS---AWSV 983

Query: 240  TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
            +  + + + D NDN+P F  S++   +SE       +V++ A DAD G N+++ Y +   
Sbjct: 984  SMDVTVVVTDANDNSPLFSHSVYSAVLSETKDKDVFVVQLVATDADLGQNSQIFYVIDPS 1043

Query: 300  DYTGNVDLPITIDPRSGWVYTSGQLDRETQA--KYQLLVTATDGGDPPRSATATXXXXXX 357
            +    V+ P      SG +++   L     +   YQ  V A D GD P  +  T      
Sbjct: 1044 NEEFWVNSP------SGEIFSKKPLTLPNSSFELYQFTVFAFDCGDAPLRSNTTVTVRLE 1097

Query: 358  XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR---LHYEITGGNTRGRFSI 414
                    F+P +  +        GT VV  TA D D +N    + Y + GGN    F +
Sbjct: 1098 PINFHPPSFLPHRRLIPTPYHMAVGTEVVKFTAIDQDINNSSSAIKYILIGGNASSFFWL 1157

Query: 415  TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYAPVFENA 472
              ++G+  + + Q ++      + L++ A D G    ++++++   IT  N + PVF   
Sbjct: 1158 QEESGK--VILEQSVEGSINSFFTLSLQAVDQGYPPLSSLIEVTFEITGRNQFPPVFREP 1215

Query: 473  PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
              T SV ED  +G+ +  + A D D G N  I+Y  + E       + D    +   +G 
Sbjct: 1216 DVTFSVPEDLVVGSPIGRIHAEDRDYGTNGAISYGFTHE-------NQDSPLSVGEHSGI 1268

Query: 533  ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592
            +T  K LD ET   Y L + A+DG   + S   +V + V+DVNDN PVF    YT ++ E
Sbjct: 1269 LTLIKELDFETDRIYHLQMEAKDGAWFTKSSPLNVTVIVLDVNDNPPVFLSSSYTISVPE 1328

Query: 593  DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652
            ++ +GTS+  V A DAD   N ++ Y L     ++  F IDP SG I T+   D E    
Sbjct: 1329 NSEIGTSILDVKADDADSSSNAQMLYSLFSGRMDK--FAIDPGSGTITTSDIFDYEQERV 1386

Query: 653  HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
             ++   A++ G  P  S   V I+I D+N+  P F+ +   F +  N+ IGT +G + A 
Sbjct: 1387 FEVTVRAMNAGAHPLFSVARVVIQITDVNEFTPTFDKNQYHFIVFRNARIGTRVGRVTAT 1446

Query: 713  DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP 772
            D D GP   V Y++ G   +  F ++   G      +     D     K     +   + 
Sbjct: 1447 DGDSGPAGQVFYTMFGQSKTKGFEIDNISGEIYTSGILREQADSRILLKVLARNLGVVTG 1506

Query: 773  PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRIL 832
               ++  V I VT+   NAPV        N  +D         V   D D + ++ + I 
Sbjct: 1507 VDVDETSVHISVTEF--NAPVFTSSIYSANITEDSRAGSSVITVGVLDQD-SSRVIFSIE 1563

Query: 833  SGNNANLILLNETTGSMTLSPQLN 856
            +GN     +++ ++G ++++ +L+
Sbjct: 1564 NGNTDLAFVVDPSSGVISVNSELD 1587



 Score =  267 bits (654), Expect = 3e-69
 Identities = 217/778 (27%), Positives = 359/778 (46%), Gaps = 45/778 (5%)

Query: 87  QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146
           + +F +   SG  L   SLD E  + Y + V      S VS     + +++ N++D NDN
Sbjct: 15  ESLFLLSPLSGEFLLSRSLDFEVQSLYILTVMVQQGDSQVS-----SVSVYFNVLDVNDN 69

Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206
            P FS  T++  + ED  V        +  +D D G N  ++ ++ G +    F I+  S
Sbjct: 70  PPVFSRGTFSAFLLEDTRV--GTCFLSLNVSDKDSGDNGDVKLSVDGEDEDQVFFINP-S 126

Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSP---SRSNTTQLLINIRDVNDNAPRFYTSLFQ 263
             + L   LD E    Y + + A D   P     ++T ++ + + DVNDNAPRF  S   
Sbjct: 127 SSLCLKAELDREMQNFYNVTVTASDRVQPPALQLTSTARVYVTVGDVNDNAPRF-VSANT 185

Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323
             ++E+  +   I+ ++  D D+G NA + Y +         +   +ID  SG ++    
Sbjct: 186 VKITEDAALHSVIMTIRTEDDDDGSNALVLYYLNT-----TAEGTFSIDSSSGEIHLMEM 240

Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383
           L+RE      L VTA D G P  + +++              F    Y+V + ED   GT
Sbjct: 241 LNRELHDSLILTVTAIDEGSPRMTTSSSLTVLIEDVNNHDPEFSTDLYKVAVREDVRGGT 300

Query: 384 PVVTLTATDADEDNRLHYEITGGNTRGR-FSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
            ++ ++A   D D  ++ E+     + R FS+ +   RG++ V + LD + +  Y LT++
Sbjct: 301 SLLQVSA--LDRDIGMNGEVRYMLDKARPFSVDAV--RGVVMVMERLDRESDAEYTLTLT 356

Query: 443 ATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFE-DAPIGTTVLVVSATDSDVG 499
           A D G   RS TA++ I + D N++ P F     T  V E +         VSA D D G
Sbjct: 357 AVDLGEPPRSTTAVINITVMDINDFVPSFNPELLTLHVMENEEDFSKLTYQVSALDEDFG 416

Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
            N+Q+ Y +        ++ ++  F I    G       LDRE  + +++T+ A D G  
Sbjct: 417 ANSQLQYFI--------LSGNNGHFSIT-LNGTFQILHSLDREVQAVHVVTIIAIDSGSH 467

Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619
            L+ T  ++I V D+NDN P F  + Y   + ED+  GT  + V A+D D G+NG + Y 
Sbjct: 468 PLTGTQTLQIIVGDINDNRPAFTGEAYNTIVSEDSPAGTVFAMVTASDIDEGVNGELSYR 527

Query: 620 LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG-TPPQSSTVIVHIKIE 678
           L   D     F ID  SG + T   LDRE+VA + L  +  D   T P SS+VIV + I 
Sbjct: 528 LAGLDM---PFAIDETSGELFTTDLLDRETVAIYRLVVIGSDKHLTWPLSSSVIVTVLIG 584

Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738
           D+ND  P F +     Y+      G+ +  + A D D   NA +HYS+  G  S+ FS++
Sbjct: 585 DVNDHWPQFMNGPYVAYVPTGMVAGSVVCAVGAVDEDIDLNAELHYSLY-GHGSDLFSID 643

Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQ 798
            R G+    + T   L +         V  A   P  +   + I   ++ +   +    +
Sbjct: 644 PRSGN----VYTTGVLQWAEDLVLNVHVEDAGETPKSDTSTISIRFQNIAEFPQI--SVE 697

Query: 799 IIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
           I+  +  +  PVG    V +  +   + + + + SGN  N   +++ +G++T+   L+
Sbjct: 698 ILNGSIPENVPVGTLVAVVSAASTRAEPVSFYLASGNLDNKFHVDQVSGALTVDNPLD 755



 Score =  250 bits (611), Expect = 6e-64
 Identities = 189/617 (30%), Positives = 297/617 (48%), Gaps = 41/617 (6%)

Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           I Y+++  + +  F +  LSG+  L ++LD+E    Y L +  Q G S  + ++  +  N
Sbjct: 5   ITYSVLEDDGESLFLLSPLSGEFLLSRSLDFEVQSLYILTVMVQQGDS--QVSSVSVYFN 62

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
           + DVNDN P F    F   + E+  +G   + +   D D G N ++  ++  +D     D
Sbjct: 63  VLDVNDNPPVFSRGTFSAFLLEDTRVGTCFLSLNVSDKDSGDNGDVKLSVDGED----ED 118

Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR---SATATXXXXXXXXXXXX 363
               I+P S  +    +LDRE Q  Y + VTA+D   PP    ++TA             
Sbjct: 119 QVFFINPSSS-LCLKAELDREMQNFYNVTVTASDRVQPPALQLTSTARVYVTVGDVNDNA 177

Query: 364 XXFMPGQYEVELAEDEPPGTPVVTL-TATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422
             F+     V++ ED    + ++T+ T  D D  N L          G FSI S +G   
Sbjct: 178 PRFVSAN-TVKITEDAALHSVIMTIRTEDDDDGSNALVLYYLNTTAEGTFSIDSSSGE-- 234

Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480
           I + + L+ +     +LTV+A D G    + ++ + + I D NN+ P F    Y  +V E
Sbjct: 235 IHLMEMLNRELHDSLILTVTAIDEGSPRMTTSSSLTVLIEDVNNHDPEFSTDLYKVAVRE 294

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           D   GT++L VSA D D+G+N ++ Y L             + F ++   G +   + LD
Sbjct: 295 DVRGGTSLLQVSALDRDIGMNGEVRYMLDKA----------RPFSVDAVRGVVMVMERLD 344

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
           RE+ + Y LT+TA D G P  S T  + I+V+D+ND  P F  +L T ++ME+    + +
Sbjct: 345 RESDAEYTLTLTAVDLGEPPRSTTAVINITVMDINDFVPSFNPELLTLHVMENEEDFSKL 404

Query: 601 S-QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
           + QV A D D G N ++ Y +       G F I   +G  +   +LDRE  A H +  +A
Sbjct: 405 TYQVSALDEDFGANSQLQYFI--LSGNNGHFSI-TLNGTFQILHSLDREVQAVHVVTIIA 461

Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
           ID G+ P + T  + I + DIND+ P F  +     +SE+SP GT    + A D DEG N
Sbjct: 462 IDSGSHPLTGTQTLQIIVGDINDNRPAFTGEAYNTIVSEDSPAGTVFAMVTASDIDEGVN 521

Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP----PLW 775
             + Y + G D    F+++   G    EL T   LD E+    Y LV+  +      PL 
Sbjct: 522 GELSYRLAGLD--MPFAIDETSG----ELFTTDLLDRETV-AIYRLVVIGSDKHLTWPLS 574

Query: 776 NDVRVEILVTDVNDNAP 792
           + V V +L+ DVND+ P
Sbjct: 575 SSVIVTVLIGDVNDHWP 591



 Score =  208 bits (507), Expect = 2e-51
 Identities = 168/572 (29%), Positives = 271/572 (47%), Gaps = 36/572 (6%)

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
           + P SG    S  LD E Q+ Y L V    G     S +                F  G 
Sbjct: 20  LSPLSGEFLLSRSLDFEVQSLYILTVMVQQGDSQVSSVSV--YFNVLDVNDNPPVFSRGT 77

Query: 371 YEVELAEDEPPGTPVVTLTATDADE-DNR-LHYEITGGNTRGRFSITSQNGRGLITVAQP 428
           +   L ED   GT  ++L  +D D  DN  +   + G +    F I   N    + +   
Sbjct: 78  FSAFLLEDTRVGTCFLSLNVSDKDSGDNGDVKLSVDGEDEDQVFFI---NPSSSLCLKAE 134

Query: 429 LDFKQERRYVLTVSATD-----SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
           LD + +  Y +TV+A+D     +   + TA V + + D N+ AP F +A  T  + EDA 
Sbjct: 135 LDREMQNFYNVTVTASDRVQPPALQLTSTARVYVTVGDVNDNAPRFVSAN-TVKITEDAA 193

Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
           + + ++ +   D D G NA + Y L++             F I+  +G I   ++L+RE 
Sbjct: 194 LHSVIMTIRTEDDDDGSNALVLYYLNTTAEGT--------FSIDSSSGEIHLMEMLNREL 245

Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
               +LTVTA D G P ++ ++ + + + DVN+++P F   LY   + ED   GTS+ QV
Sbjct: 246 HDSLILTVTAIDEGSPRMTTSSSLTVLIEDVNNHDPEFSTDLYKVAVREDVRGGTSLLQV 305

Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
            A D D+G+NG + Y LD K R    F +D   GV+   + LDRES A + L   A+D G
Sbjct: 306 SALDRDIGMNGEVRYMLD-KAR---PFSVDAVRGVVMVMERLDRESDAEYTLTLTAVDLG 361

Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN-SPIGTTIGEIRAHDPDEGPNAVV 722
            PP+S+T +++I + DIND  P F  + LT ++ EN         ++ A D D G N+ +
Sbjct: 362 EPPRSTTAVINITVMDINDFVPSFNPELLTLHVMENEEDFSKLTYQVSALDEDFGANSQL 421

Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEI 782
            Y I  G++ + FS+ T  G+   +++  +D + ++      + I + S PL     ++I
Sbjct: 422 QYFILSGNNGH-FSI-TLNGT--FQILHSLDREVQAVHVVTIIAIDSGSHPLTGTQTLQI 477

Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDAD--VTDKLQYRILSGNNANL 839
           +V D+NDN P     +       +  P G  F  V A D D  V  +L YR L+G +   
Sbjct: 478 IVGDINDNRPAFTG-EAYNTIVSEDSPAGTVFAMVTASDIDEGVNGELSYR-LAGLDMP- 534

Query: 840 ILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
             ++ET+G +  +  L+     +  + V  +D
Sbjct: 535 FAIDETSGELFTTDLLDRETVAIYRLVVIGSD 566



 Score = 67.7 bits (158), Expect = 4e-09
 Identities = 52/172 (30%), Positives = 74/172 (43%), Gaps = 20/172 (11%)

Query: 1044 CQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVC 1103
            CQC  GF G  CE  +    C      S C  GS C+  + G      C      +   C
Sbjct: 2036 CQCVSGFEGEMCERFIDH--CR----SSPCIQGS-CINSQTGF----SCDCPFGVSGVHC 2084

Query: 1104 ELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSE 1163
            +  +  F   SF+ FP L RR  + + L+FAT   + LLLYN       +FLALE++   
Sbjct: 2085 DELSYGFQEMSFIEFPPLDRRINL-VSLEFATLQKNSLLLYNPGGPSSREFLALEILDG- 2142

Query: 1164 AGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDC 1215
                    +  S+ LG G   +     V DG +HTV I       ++ +D+C
Sbjct: 2143 -------AVHLSYDLGSGPERLQTNIQVSDGDFHTVTIRRIGYMGSLRVDNC 2187



 Score = 37.9 bits (84), Expect = 4.0
 Identities = 21/65 (32%), Positives = 25/65 (38%), Gaps = 5/65 (7%)

Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSC 1573
            C   IC     CV       C C +G  G  C   +  C   PC    C+  QT  G+SC
Sbjct: 2016 CTDLICQNGGTCVVRPGGQHCQCVSGFEGEMCERFIDHCRSSPCIQGSCINSQT--GFSC 2073

Query: 1574 ACEPG 1578
             C  G
Sbjct: 2074 DCPFG 2078


>UniRef50_Q9H251 Cluster: Cadherin-23 precursor; n=51;
            Euteleostomi|Rep: Cadherin-23 precursor - Homo sapiens
            (Human)
          Length = 3354

 Score =  355 bits (872), Expect = 1e-95
 Identities = 274/879 (31%), Positives = 424/879 (48%), Gaps = 59/879 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +N+LD ND+ P F+   + A V EG  +G ++  + A D D G N  V Y +  V    +
Sbjct: 878  VNLLDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRMP-VGMPRM 936

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +                  F I+  SG ++T   LDRE++A Y + V A+D  +P     
Sbjct: 937  D------------------FLINSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTK--- 975

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            SST+T+ ++++D ND  P F    Y VSV ED+       +  +  TD DVG N+ + Y 
Sbjct: 976  SSTSTLTIHVLDVNDETPTFFPAVYNVSVSEDVPREFR--VVWLNCTDNDVGLNAELSYF 1033

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR--SNTTQLLINIR 248
            I GGN   +FS+      V  V  LD E   +Y L++ A D G   +  + T  + + + 
Sbjct: 1034 ITGGNVDGKFSVGYRDAVVRTVVGLDRETTAAYMLILEAIDNGPVGKRHTGTATVFVTVL 1093

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            DVNDN P F  S ++ SV E++P G+SI++++A DADEG    + Y +   ++  N  + 
Sbjct: 1094 DVNDNRPIFLQSSYEASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIH 1153

Query: 309  ITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
            ++    +G +    + LDRE  + + L+V A +    P  ++                F 
Sbjct: 1154 VS----NGLLMRGPRPLDRERNSSHVLIVEAYNHDLGPMRSSVRVIVYVEDINDEAPVFT 1209

Query: 368  PGQY-EVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLIT 424
              QY  + L E    GT V+ + ATD D  +   ++Y I  G   G+F I      GLI 
Sbjct: 1210 QQQYSRLGLRETAGIGTSVIVVQATDRDSGDGGLVNYRILSG-AEGKFEI--DESTGLII 1266

Query: 425  VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDAN--NYAPVFENAPYTASVFEDA 482
                LD++ +  Y++ VSATD     +     + IT  N  + A  F NA Y A++ E+ 
Sbjct: 1267 TVNYLDYETKTSYMMNVSATDQAPPFNQGFCSVYITLLNELDEAVQFSNASYEAAILENL 1326

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
             +GT ++ V A   D  +N QITY   +  S +A A     F I+  TG IT   L+DRE
Sbjct: 1327 ALGTEIVRVQAYSID-NLN-QITYRFDAYTSTQAKA----LFKIDAITGVITVQGLVDRE 1380

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA-NIMEDALVGTSVS 601
                Y LTV A DGG P +  T  V I+V+D NDN P F     +A +I ED  VG  V+
Sbjct: 1381 KGDFYTLTVVADDGG-PKVDSTVKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVGQRVA 1439

Query: 602  QVGATDADVGLNGRIHYELDPKDREEGSFVI---DPASGVIRTNKALDRESVATHDLKAV 658
             V A D D G NG++ + L       G+F I   + + G +   + LDRE +  + L+ V
Sbjct: 1440 TVKAWDPDAGSNGQVVFSL-ASGNIAGAFEIVTTNDSIGEVFVARPLDREELDHYILQVV 1498

Query: 659  AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC-LTFYISENSPIGTTIGEIRAHDPDEG 717
            A D GTPP+    I+ + I DIND+PPV ES       ++EN   GT + ++RA D D G
Sbjct: 1499 ASDRGTPPRKKDHILQVTILDINDNPPVIESPFGYNVSVNENVGGGTAVVQVRATDRDIG 1558

Query: 718  PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND 777
             N+V+ Y I  G+   +F ++ R   + A      D + +S       V    +P L   
Sbjct: 1559 INSVLSYYITEGNKDMTFRMD-RISGEIATRPAPPDRERQSFYHLVATVEDEGTPTLSAT 1617

Query: 778  VRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILS 833
              V + + D NDNAP+ +   ++++ +   D         + A D D      + Y I++
Sbjct: 1618 THVYVTIVDENDNAPMFQQPHYEVLLDEGPDTLNTSLI-TIQALDLDEGPNGTVTYAIVA 1676

Query: 834  GNNANLILLNETTGSMTLSPQLNTNVPK-LATMEVSVTD 871
            GN  N   ++   G +T + +L+  +     T+ V+ TD
Sbjct: 1677 GNIVNTFRIDRHMGVITAAKELDYEISHGRYTLIVTATD 1715



 Score =  350 bits (861), Expect = 3e-94
 Identities = 274/832 (32%), Positives = 400/832 (48%), Gaps = 85/832 (10%)

Query: 10   QINVLDCNDHSPVFEMQ-QYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68
            Q+ +LD ND+ PV E    Y  SV E    GT V+ ++ATD+DIG N+ + Y I     D
Sbjct: 1514 QVTILDINDNPPVIESPFGYNVSVNENVGGGTAVVQVRATDRDIGINSVLSYYITEGNKD 1573

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR-ASLDREKVARYTVLVKATDQASPVS 127
                                 FR+D  SG + TR A  DRE+ + Y ++    D+ +P  
Sbjct: 1574 M-------------------TFRMDRISGEIATRPAPPDRERQSFYHLVATVEDEGTPT- 1613

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
              LS+T  ++V I+D+NDN P F +  Y V +DE     +  +I  I+A D D G N  +
Sbjct: 1614 --LSATTHVYVTIVDENDNAPMFQQPHYEVLLDEGPDTLNTSLIT-IQALDLDEGPNGTV 1670

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGG---SPSRSNTTQL 243
             YAI+ GN    F ID   G ++  K LDYE     Y L++ A D     S   ++TT +
Sbjct: 1671 TYAIVAGNIVNTFRIDRHMGVITAAKELDYEISHGRYTLIVTATDQCPILSHRLTSTTTV 1730

Query: 244  LINIRDVNDNAPRF---YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
            L+N+ D+NDN P F   Y   F+  V+E  P G  +    A+D D G N ++ Y++ D D
Sbjct: 1731 LVNVNDINDNVPTFPRDYEGPFE--VTEGQP-GPRVWTFLAHDRDSGPNGQVEYSIMDGD 1787

Query: 301  YTGNVDLPITIDPRSGW--VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358
              G       I P  G   V    +LDRET A Y L + A D G PP S+T         
Sbjct: 1788 PLGE----FVISPVEGVLRVRKDVELDRETIAFYNLTICARDRGMPPLSSTMLVGIRVLD 1843

Query: 359  XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITS 416
                    +     + ++E+ P  + V  + A+DAD   + RL + IT GN    F I +
Sbjct: 1844 INDNDPVLLNLPMNITISENSPVSSFVAHVLASDADSGCNARLTFNITAGNRERAFFINA 1903

Query: 417  QNGRGLITVAQPLDFKQERRYVLTVSATDSG-----GRSDTAMVQINITDANNYAPVFEN 471
              G  ++TV +PLD ++   Y LT+S  D+       R D  ++ I ++D N+  P+F  
Sbjct: 1904 TTG--IVTVNRPLDRERIPEYKLTISVKDNPENPRIARRDYDLLLIFLSDENDNHPLFTK 1961

Query: 472  APYTASVFEDAPIGTTVLVVS----ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527
            + Y A V E++P GT + V++    A D+D  I A +TY L    S          F IN
Sbjct: 1962 STYQAEVMENSPAGTPLTVLNGPILALDADQDIYAVVTYQLLGAQSG--------LFDIN 2013

Query: 528  PQTGAITTNK--LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585
              TG +T     ++DRE  S  +L +      +  L+ T  + I+++D NDN P F    
Sbjct: 2014 SSTGVVTVRSGVIIDREAFSPPILELLLLAEDIGLLNSTAHLLITILDDNDNRPTFSPAT 2073

Query: 586  YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT-NKA 644
             T +++E+   G SV QV ATD D GLNG + Y ++   ++   F+I   +GVIR  N  
Sbjct: 2074 LTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDR--FLIHLVTGVIRVGNAT 2131

Query: 645  LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
            +DRE   ++ L  VA D GT P S T IV I I+DINDS P F +   T  + E++  GT
Sbjct: 2132 IDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAEPGT 2191

Query: 705  TIGEIRAHDPDEGPNAVVH-YSIKGGDDS--------NSFSLETRQGS------DKAELV 749
             I  I A D D  P    H   I   DD+        ++F++    GS         ELV
Sbjct: 2192 VIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNINTGSVMVKSPMNRELV 2251

Query: 750  TMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801
               ++         +L  R+ S P   + ++ + V DVNDN P  K F I +
Sbjct: 2252 ATYEVTLSVIDNASDLPERSVSVP---NAKLTVNVLDVNDNTPQFKPFGITY 2300



 Score =  349 bits (857), Expect = 9e-94
 Identities = 268/859 (31%), Positives = 406/859 (47%), Gaps = 51/859 (5%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I +LD ND+ P ++   Y  ++ E     + V T+ A D D+G+N  + Y+I+       
Sbjct: 766  ITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQ------- 818

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             P +           ++    +  R       A L R+      ++V  TD   P   + 
Sbjct: 819  -PPNKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRK------IVVSVTDCGRPPL-KA 870

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +S+AT+ VN++D NDN P F    +   V E I    +  I ++ A D D G N  + Y 
Sbjct: 871  TSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGIPAGVS--IYQVVAIDLDEGLNGLVSYR 928

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            +  G  +M F I+S SG V     LD E++  Y+L + A D G+P++S+T+ L I++ DV
Sbjct: 929  MPVGMPRMDFLINSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDV 988

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            ND  P F+ +++  SVSE+VP  + +V +   D D G+NAEL+Y +T     GNVD   +
Sbjct: 989  NDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITG----GNVDGKFS 1044

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR--SATATXXXXXXXXXXXXXXFMP 368
            +  R   V T   LDRET A Y L++ A D G   +  + TAT              F+ 
Sbjct: 1045 VGYRDAVVRTVVGLDRETTAAYMLILEAIDNGPVGKRHTGTATVFVTVLDVNDNRPIFLQ 1104

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVA 426
              YE  + ED P G  ++ L ATDADE    R+ Y I  GN    F I   NG  L+   
Sbjct: 1105 SSYEASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHVSNGL-LMRGP 1163

Query: 427  QPLDFKQERRYVLTVSA--TDSGGRSDTAMVQINITDANNYAPVFENAPYT-ASVFEDAP 483
            +PLD ++   +VL V A   D G    +  V + + D N+ APVF    Y+   + E A 
Sbjct: 1164 RPLDRERNSSHVLIVEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAG 1223

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
            IGT+V+VV ATD D G    + Y + S          + +F I+  TG I T   LD ET
Sbjct: 1224 IGTSVIVVQATDRDSGDGGLVNYRILSGA--------EGKFEIDESTGLIITVNYLDYET 1275

Query: 544  MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
             + Y++ V+A D   P       V I++++  D    F    Y A I+E+  +GT + +V
Sbjct: 1276 KTSYMMNVSATDQAPPFNQGFCSVYITLLNELDEAVQFSNASYEAAILENLALGTEIVRV 1335

Query: 604  GATDADVGLNGRIHYELD--PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
             A   D  LN +I Y  D     + +  F ID  +GVI     +DRE    + L  VA D
Sbjct: 1336 QAYSID-NLN-QITYRFDAYTSTQAKALFKIDAITGVITVQGLVDREKGDFYTLTVVADD 1393

Query: 662  GGTPPQSSTVIVHIKIEDINDSPPVFE-SDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
            GG P   STV V+I + D ND+ P F+ +      I E+ P+G  +  ++A DPD G N 
Sbjct: 1394 GG-PKVDSTVKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVGQRVATVKAWDPDAGSNG 1452

Query: 721  VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWND 777
             V +S+  G+ + +F + T   S   E+     LD E     Y L + A+   +PP   D
Sbjct: 1453 QVVFSLASGNIAGAFEIVTTNDS-IGEVFVARPLDREE-LDHYILQVVASDRGTPPRKKD 1510

Query: 778  VRVEILVTDVNDNAPVMKD---FQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSG 834
              +++ + D+NDN PV++    + +  N            R    D  +   L Y I  G
Sbjct: 1511 HILQVTILDINDNPPVIESPFGYNVSVNENVGGGTAVVQVRATDRDIGINSVLSYYITEG 1570

Query: 835  NNANLILLNETTGSMTLSP 853
            N      ++  +G +   P
Sbjct: 1571 NKDMTFRMDRISGEIATRP 1589



 Score =  338 bits (831), Expect = 1e-90
 Identities = 266/889 (29%), Positives = 409/889 (46%), Gaps = 75/889 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I +++ ND+ P+F    Y  S+ E  + GT+VLT+ ATD D G   EV Y         
Sbjct: 447  KITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFFS------ 500

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
               +D             D F +D  +G ++  A LD E + R+T+ + A D        
Sbjct: 501  ---DD------------PDRFSLDKDTGLIMLIARLDYELIQRFTLTIIARDGGGE---- 541

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE-DISVTDNPVIAKIKATDADVGANSAIR 188
              +T  + +N++D NDN P F +  Y  ++ E + SVT    + +++ATD D   N+ I 
Sbjct: 542  -ETTGRVRINVLDVNDNVPTFQKDAYVGALRENEPSVTQ---LVRLRATDEDSPPNNQIT 597

Query: 189  YAIIGGN---TQMQFSIDSLSGDVSLVKTLDYEQVRS--YRLVIRAQDGGSPSRSNTTQL 243
            Y+I+  +   +    S+    G +S+ + LDYEQ+ +    L + A D G+P  ++T  +
Sbjct: 598  YSIVSASAFGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPV 657

Query: 244  LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
             I + D NDN P F    +  SV EN+  G +++ + A D D        Y      Y+ 
Sbjct: 658  TIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDR----SREYGQESIIYSL 713

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG--GDPPRSATATXXXXXXXXXX 361
                   I+ RSG + T+  LDRET+++Y L+V A DG  G   ++  AT          
Sbjct: 714  EGSTQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDIND 773

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419
                +    Y + L E  PP + V T+ A D D  E+  L Y I   N    +S+ S  G
Sbjct: 774  NHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQPPNK--FYSLNSTTG 831

Query: 420  R-----GLITVAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNYAPVFE 470
            +      ++    P   + E    + VS TD G      + +A V +N+ D N+  P F+
Sbjct: 832  KIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQ 891

Query: 471  NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
            N P+ A V E  P G ++  V A D D G+N  ++Y +        V      F+IN  +
Sbjct: 892  NLPFVAEVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRM-------PVGMPRMDFLINSSS 944

Query: 531  GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590
            G + T   LDRE ++ Y L V A D G P+ S T+ + I V+DVND  P F   +Y  ++
Sbjct: 945  GVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDETPTFFPAVYNVSV 1004

Query: 591  MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650
             ED      V  +  TD DVGLN  + Y +      +G F +     V+RT   LDRE+ 
Sbjct: 1005 SEDVPREFRVVWLNCTDNDVGLNAELSYFI-TGGNVDGKFSVGYRDAVVRTVVGLDRETT 1063

Query: 651  ATHDLKAVAIDGGT--PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
            A + L   AID G      + T  V + + D+ND+ P+F        + E+ P G +I +
Sbjct: 1064 AAYMLILEAIDNGPVGKRHTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSILQ 1123

Query: 709  IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768
            ++A D DEG    V Y I  G+  N+F +    G     +     LD E     + L++ 
Sbjct: 1124 LKATDADEGEFGRVWYRILHGNHGNNFRIHVSNG---LLMRGPRPLDRER-NSSHVLIVE 1179

Query: 769  AAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVT 824
            A +    P+ + VRV + V D+ND APV    Q      ++   +G     V A D D  
Sbjct: 1180 AYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAGIGTSVIVVQATDRDSG 1239

Query: 825  D--KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            D   + YRILSG       ++E+TG +     L+        M VS TD
Sbjct: 1240 DGGLVNYRILSGAEGK-FEIDESTGLIITVNYLDYETKTSYMMNVSATD 1287



 Score =  336 bits (825), Expect = 7e-90
 Identities = 274/889 (30%), Positives = 419/889 (47%), Gaps = 83/889 (9%)

Query: 8    HQQINVLDCNDHSPVFEMQQYEASVREGASS-GTTVLTLKATDQDIGKNAEVEYTIELVT 66
            H  + ++D ND++P+F+   YE  + EG  +  T+++T++A D D G N  V Y I  V 
Sbjct: 1619 HVYVTIVDENDNAPMFQQPHYEVLLDEGPDTLNTSLITIQALDLDEGPNGTVTYAI--VA 1676

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDRE-KVARYTVLVKATDQASP 125
             + +N                  FRID   G +     LD E    RYT++V ATDQ   
Sbjct: 1677 GNIVN-----------------TFRIDRHMGVITAAKELDYEISHGRYTLIVTATDQCPI 1719

Query: 126  VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
            +S RL+ST T+ VN+ D NDN P F  + Y     E       P +    A D D G N 
Sbjct: 1720 LSHRLTSTTTVLVNVNDINDNVPTF-PRDYE-GPFEVTEGQPGPRVWTFLAHDRDSGPNG 1777

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVK--TLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
             + Y+I+ G+   +F I  + G + + K   LD E +  Y L I A+D G P  S+T  +
Sbjct: 1778 QVEYSIMDGDPLGEFVISPVEGVLRVRKDVELDRETIAFYNLTICARDRGMPPLSSTMLV 1837

Query: 244  LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
             I + D+NDN P         ++SEN P+   +  V A DAD G NA LT+ +T     G
Sbjct: 1838 GIRVLDINDNDPVLLNLPMNITISENSPVSSFVAHVLASDADSGCNARLTFNIT----AG 1893

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
            N +    I+  +G V  +  LDRE   +Y+L ++  D  + PR A               
Sbjct: 1894 NRERAFFINATTGIVTVNRPLDRERIPEYKLTISVKDNPENPRIARRDYDLLLIFLSDEN 1953

Query: 364  X---XFMPGQYEVELAEDEPPGTPVVTLT----ATDADED--NRLHYEITGGNTRGRFSI 414
                 F    Y+ E+ E+ P GTP+  L     A DAD+D    + Y++ G  + G F I
Sbjct: 1954 DNHPLFTKSTYQAEVMENSPAGTPLTVLNGPILALDADQDIYAVVTYQLLGAQS-GLFDI 2012

Query: 415  TSQNGRGLITVAQPLDFKQER----RYVLTVSATDSGGRSDTAMVQINITDANNYAPVFE 470
             S    G++TV   +   +E        L + A D G  + TA + I I D N+  P F 
Sbjct: 2013 NSST--GVVTVRSGVIIDREAFSPPILELLLLAEDIGLLNSTAHLLITILDDNDNRPTFS 2070

Query: 471  NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
             A  T  + E+ P G +VL V+ATD D G+N ++ Y +      EA A    +F+I+  T
Sbjct: 2071 PATLTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRI------EAGA--QDRFLIHLVT 2122

Query: 531  GAITT-NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589
            G I   N  +DRE    Y LTV A D G   LS T  V I + D+ND+ P F   + T +
Sbjct: 2123 GVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVS 2182

Query: 590  IMEDALVGTSVSQVGATDADVGLNGRIHYEL------DPKDR----EEGSFVIDPASGVI 639
            ++E A  GT ++ + A D D  LN ++ Y +      D  DR    +E +F ++  +G +
Sbjct: 2183 VLESAEPGTVIANITAIDHD--LNPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNINTGSV 2240

Query: 640  RTNKALDRESVATHDLKAVAIDGGTP-PQSSTVIVHIKIE----DINDSPPVFESDCLTF 694
                 ++RE VAT+++    ID  +  P+ S  + + K+     D+ND+ P F+   +T+
Sbjct: 2241 MVKSPMNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNVLDVNDNTPQFKPFGITY 2300

Query: 695  Y---ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751
            Y   I E +  GTT+  + A DPD+G N +V Y++          LE    S   +++  
Sbjct: 2301 YMERILEGATPGTTLIAVAAVDPDKGLNGLVTYTLLDLVPPGYVQLE---DSSAGKVIAN 2357

Query: 752  VDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCF 808
              +DYE         +RA+   SPP   ++ V + + D+NDN P+          ++D  
Sbjct: 2358 RTVDYEEVH-WLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFED-V 2415

Query: 809  PVGP-FGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
            PVG     V A DAD  +        G+  +   +N TTG + +   L+
Sbjct: 2416 PVGTIILTVTATDADSGNFALIEYSLGDGESKFAINPTTGDIYVLSSLD 2464



 Score =  330 bits (811), Expect = 3e-88
 Identities = 277/882 (31%), Positives = 411/882 (46%), Gaps = 62/882 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + VLD ND+ P+F    YEASV E    G ++L LKATD D G+   V Y I       L
Sbjct: 1090 VTVLDVNDNRPIFLQSSYEASVPEDIPEGHSILQLKATDADEGEFGRVWYRI-------L 1142

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS-LDREKVARYTVLVKATDQASPVSDR 129
            +                  FRI   +G L+     LDRE+ + + ++V+A +        
Sbjct: 1143 HGNHGNN------------FRIHVSNGLLMRGPRPLDRERNSSHVLIVEAYNHDL---GP 1187

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYT-VSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            + S+  + V + D ND  P F+++ Y+ + + E   +  + ++  ++ATD D G    + 
Sbjct: 1188 MRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAGIGTSVIV--VQATDRDSGDGGLVN 1245

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            Y I+ G  + +F ID  +G +  V  LDYE   SY + + A D   P       + I + 
Sbjct: 1246 YRILSG-AEGKFEIDESTGLIITVNYLDYETKTSYMMNVSATDQAPPFNQGFCSVYITLL 1304

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            +  D A +F  + ++ ++ EN+ +G  IVRVQAY  D  +N ++TY   D   +      
Sbjct: 1305 NELDEAVQFSNASYEAAILENLALGTEIVRVQAYSIDN-LN-QITYRF-DAYTSTQAKAL 1361

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
              ID  +G +   G +DRE    Y L V A DGG    S                     
Sbjct: 1362 FKIDAITGVITVQGLVDREKGDFYTLTVVADDGGPKVDSTVKVYITVLDENDNSPRFDFT 1421

Query: 369  GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGR-GLITV 425
                V + ED P G  V T+ A D D   + ++ + +  GN  G F I + N   G + V
Sbjct: 1422 SDSAVSIPEDCPVGQRVATVKAWDPDAGSNGQVVFSLASGNIAGAFEIVTTNDSIGEVFV 1481

Query: 426  AQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENA-PYTASVFEDA 482
            A+PLD ++   Y+L V A+D G   R    ++Q+ I D N+  PV E+   Y  SV E+ 
Sbjct: 1482 ARPLDREELDHYILQVVASDRGTPPRKKDHILQVTILDINDNPPVIESPFGYNVSVNENV 1541

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL-DR 541
              GT V+ V ATD D+GIN+ ++Y ++         + D  F ++  +G I T     DR
Sbjct: 1542 GGGTAVVQVRATDRDIGINSVLSYYITE-------GNKDMTFRMDRISGEIATRPAPPDR 1594

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA-LVGTSV 600
            E  S Y L  T  D G P+LS TT V +++VD NDN P+F+Q  Y   + E    + TS+
Sbjct: 1595 ERQSFYHLVATVEDEGTPTLSATTHVYVTIVDENDNAPMFQQPHYEVLLDEGPDTLNTSL 1654

Query: 601  SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE-SVATHDLKAVA 659
              + A D D G NG + Y +        +F ID   GVI   K LD E S   + L   A
Sbjct: 1655 ITIQALDLDEGPNGTVTYAI-VAGNIVNTFRIDRHMGVITAAKELDYEISHGRYTLIVTA 1713

Query: 660  IDGG---TPPQSSTVIVHIKIEDINDSPPVFESDCL-TFYISENSPIGTTIGEIRAHDPD 715
             D     +   +ST  V + + DIND+ P F  D    F ++E  P G  +    AHD D
Sbjct: 1714 TDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEGPFEVTEGQP-GPRVWTFLAHDRD 1772

Query: 716  EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---P 772
             GPN  V YSI  GD    F +   +G  +      V+LD E+    Y L I A     P
Sbjct: 1773 SGPNGQVEYSIMDGDPLGEFVISPVEGVLRVR--KDVELDRETIAF-YNLTICARDRGMP 1829

Query: 773  PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDAD--VTDKLQY 829
            PL + + V I V D+NDN PV+ +  +     ++  PV  F   V A DAD     +L +
Sbjct: 1830 PLSSTMLVGIRVLDINDNDPVLLNLPMNITISENS-PVSSFVAHVLASDADSGCNARLTF 1888

Query: 830  RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
             I +GN      +N TTG +T++  L+        + +SV D
Sbjct: 1889 NITAGNRERAFFINATTGIVTVNRPLDRERIPEYKLTISVKD 1930



 Score =  327 bits (803), Expect = 3e-87
 Identities = 273/868 (31%), Positives = 416/868 (47%), Gaps = 76/868 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I +L+  D +  F    YEA++ E  + GT ++ ++A            Y+I     D L
Sbjct: 1301 ITLLNELDEAVQFSNASYEAAILENLALGTEIVRVQA------------YSI-----DNL 1343

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N +             + +F+ID  +G +  +  +DREK   YT+ V A D   P   ++
Sbjct: 1344 N-QITYRFDAYTSTQAKALFKIDAITGVITVQGLVDREKGDFYTLTVVA-DDGGP---KV 1398

Query: 131  SSTATIHVNIIDDNDNYPQFS-EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             ST  +++ ++D+NDN P+F       VS+ ED  V     +A +KA D D G+N  + +
Sbjct: 1399 DSTVKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVGQR--VATVKAWDPDAGSNGQVVF 1456

Query: 190  AIIGGNTQMQFSI----DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
            ++  GN    F I    DS+ G+V + + LD E++  Y L + A D G+P R     L +
Sbjct: 1457 SLASGNIAGAFEIVTTNDSI-GEVFVARPLDREELDHYILQVVASDRGTPPRKKDHILQV 1515

Query: 246  NIRDVNDNAPRFYTSL-FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
             I D+NDN P   +   +  SV+ENV  G ++V+V+A D D G+N+ L+Y +T+    GN
Sbjct: 1516 TILDINDNPPVIESPFGYNVSVNENVGGGTAVVQVRATDRDIGINSVLSYYITE----GN 1571

Query: 305  VDLPITIDPRSGWVYTS-GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
             D+   +D  SG + T     DRE Q+ Y L+ T  D G P  SAT              
Sbjct: 1572 KDMTFRMDRISGEIATRPAPPDRERQSFYHLVATVEDEGTPTLSATTHVYVTIVDENDNA 1631

Query: 364  XXFMPGQYEVELAED-EPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGR 420
              F    YEV L E  +   T ++T+ A D DE  +  + Y I  GN    F I      
Sbjct: 1632 PMFQQPHYEVLLDEGPDTLNTSLITIQALDLDEGPNGTVTYAIVAGNIVNTFRIDRH--M 1689

Query: 421  GLITVAQPLDFK-QERRYVLTVSATD-----SGGRSDTAMVQINITDANNYAPVFEN--- 471
            G+IT A+ LD++    RY L V+ATD     S   + T  V +N+ D N+  P F     
Sbjct: 1690 GVITAAKELDYEISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYE 1749

Query: 472  APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
             P+   V E  P G  V    A D D G N Q+ YS+   +  + +     +FVI+P  G
Sbjct: 1750 GPF--EVTEGQP-GPRVWTFLAHDRDSGPNGQVEYSI---MDGDPLG----EFVISPVEG 1799

Query: 532  AITTNK--LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589
             +   K   LDRET++ Y LT+ ARD G+P LS T  V I V+D+NDN+PV         
Sbjct: 1800 VLRVRKDVELDRETIAFYNLTICARDRGMPPLSSTMLVGIRVLDINDNDPVLLNLPMNIT 1859

Query: 590  IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES 649
            I E++ V + V+ V A+DAD G N R+ + +   +RE  +F I+  +G++  N+ LDRE 
Sbjct: 1860 ISENSPVSSFVAHVLASDADSGCNARLTFNITAGNRER-AFFINATTGIVTVNRPLDRER 1918

Query: 650  VATHDLKAVAIDGGTPPQSSTV---IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706
            +  + L     D    P+ +     ++ I + D ND+ P+F        + ENSP GT +
Sbjct: 1919 IPEYKLTISVKDNPENPRIARRDYDLLLIFLSDENDNHPLFTKSTYQAEVMENSPAGTPL 1978

Query: 707  ----GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762
                G I A D D+   AVV Y + G   S  F + +  G        ++D +  SP   
Sbjct: 1979 TVLNGPILALDADQDIYAVVTYQLLGAQ-SGLFDINSSTGVVTVRSGVIIDREAFSP-PI 2036

Query: 763  YELVIRAASPPLWNDV-RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDA 821
             EL++ A    L N    + I + D NDN P      +  +  ++C P     +V A D 
Sbjct: 2037 LELLLLAEDIGLLNSTAHLLITILDDNDNRPTFSPATLTVHLLENCPPGFSVLQVTATDE 2096

Query: 822  D--VTDKLQYRILSGNNANLILLNETTG 847
            D  +  +L YRI +G   +  L++  TG
Sbjct: 2097 DSGLNGELVYRIEAGAQ-DRFLIHLVTG 2123



 Score =  318 bits (780), Expect = 2e-84
 Identities = 267/872 (30%), Positives = 418/872 (47%), Gaps = 77/872 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEA-SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            + V D ND +PVF  QQY    +RE A  GT+V+ ++ATD+D G    V Y I       
Sbjct: 1196 VYVEDINDEAPVFTQQQYSRLGLRETAGIGTSVIVVQATDRDSGDGGLVNYRI------- 1248

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                             +  F ID  +G ++T   LD E    Y + V ATDQA P +  
Sbjct: 1249 -------------LSGAEGKFEIDESTGLIITVNYLDYETKTSYMMNVSATDQAPPFNQG 1295

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
              S   +++ ++++ D   QFS  +Y  ++ E++++     I +++A   D       R+
Sbjct: 1296 FCS---VYITLLNELDEAVQFSNASYEAAILENLALGTE--IVRVQAYSIDNLNQITYRF 1350

Query: 190  -AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
             A      +  F ID+++G +++   +D E+   Y L + A DGG P   +T ++ I + 
Sbjct: 1351 DAYTSTQAKALFKIDAITGVITVQGLVDREKGDFYTLTVVADDGG-PKVDSTVKVYITVL 1409

Query: 249  DVNDNAPRF-YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            D NDN+PRF +TS    S+ E+ P+G  +  V+A+D D G N ++ +++   +  G  ++
Sbjct: 1410 DENDNSPRFDFTSDSAVSIPEDCPVGQRVATVKAWDPDAGSNGQVVFSLASGNIAGAFEI 1469

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF- 366
             +T +   G V+ +  LDRE    Y L V A+D G PPR                     
Sbjct: 1470 -VTTNDSIGEVFVARPLDREELDHYILQVVASDRGTPPRKKDHILQVTILDINDNPPVIE 1528

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLIT 424
             P  Y V + E+   GT VV + ATD D   ++ L Y IT GN    F +   +G  + T
Sbjct: 1529 SPFGYNVSVNENVGGGTAVVQVRATDRDIGINSVLSYYITEGNKDMTFRMDRISGE-IAT 1587

Query: 425  VAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
               P D +++  Y L  +  D G    S T  V + I D N+ AP+F+  P+   + ++ 
Sbjct: 1588 RPAPPDRERQSFYHLVATVEDEGTPTLSATTHVYVTIVDENDNAPMFQQ-PHYEVLLDEG 1646

Query: 483  P--IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
            P  + T+++ + A D D G N  +TY++   ++   V      F I+   G IT  K LD
Sbjct: 1647 PDTLNTSLITIQALDLDEGPNGTVTYAI---VAGNIV----NTFRIDRHMGVITAAKELD 1699

Query: 541  RETMSG-YLLTVTARDGGVPSLS----DTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
             E   G Y L VTA D   P LS     TT V ++V D+NDN P F +       + +  
Sbjct: 1700 YEISHGRYTLIVTATDQ-CPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEGPFEVTEGQ 1758

Query: 596  VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK--ALDRESVATH 653
             G  V    A D D G NG++ Y +   D   G FVI P  GV+R  K   LDRE++A +
Sbjct: 1759 PGPRVWTFLAHDRDSGPNGQVEYSIMDGD-PLGEFVISPVEGVLRVRKDVELDRETIAFY 1817

Query: 654  DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713
            +L   A D G PP SST++V I++ DIND+ PV  +  +   ISENSP+ + +  + A D
Sbjct: 1818 NLTICARDRGMPPLSSTMLVGIRVLDINDNDPVLLNLPMNITISENSPVSSFVAHVLASD 1877

Query: 714  PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM-VDLDYESPRKKYELVIRAASP 772
             D G NA + ++I  G+   +F +    G     +VT+   LD E    +Y+L I     
Sbjct: 1878 ADSGCNARLTFNITAGNRERAFFINATTG-----IVTVNRPLDRER-IPEYKLTISVKDN 1931

Query: 773  PLWNDVR------VEILVTDVNDNAPVM--KDFQI-IFNNYKDCFPV----GPFGRVPAY 819
            P    +       + I ++D NDN P+     +Q  +  N     P+    GP   + A 
Sbjct: 1932 PENPRIARRDYDLLLIFLSDENDNHPLFTKSTYQAEVMENSPAGTPLTVLNGPILALDA- 1990

Query: 820  DADVTDKLQYRILSGNNANLILLNETTGSMTL 851
            D D+   + Y++L G  + L  +N +TG +T+
Sbjct: 1991 DQDIYAVVTYQLL-GAQSGLFDINSSTGVVTV 2021



 Score =  305 bits (750), Expect = 8e-81
 Identities = 256/901 (28%), Positives = 414/901 (45%), Gaps = 58/901 (6%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +INVLD ND+ P F+   Y  ++RE   S T ++ L+ATD+D   N ++ Y+I  V+A  
Sbjct: 548  RINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSI--VSASA 605

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTV--LVKATDQASPVS 127
                              D+   +G  G +     LD E+++   +   V A D  +P  
Sbjct: 606  FG-------------SYFDISLYEG-YGVISVSRPLDYEQISNGLIYLTVMAMDAGNP-- 649

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
              L+ST  + + + D+NDN P FS+  Y VSV E+I       +  + ATD D       
Sbjct: 650  -PLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMA--GATVLFLNATDLDRSREYGQ 706

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
               I       QF I++ SG+++    LD E    Y L++RA DGG      T    +NI
Sbjct: 707  ESIIYSLEGSTQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNI 766

Query: 248  R--DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM--TDKDYTG 303
               D+NDN P +  + +  ++ E  P    +  V A D D G N  L Y++   +K Y+ 
Sbjct: 767  TLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQPPNKFYSL 826

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT--ATXXXXXXXXXX 361
            N      I      +        E +   +++V+ TD G PP  AT  AT          
Sbjct: 827  N-STTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLND 885

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNG 419
                F    +  E+ E  P G  +  + A D DE  +  + Y +  G  R  F I S + 
Sbjct: 886  NDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRMPVGMPRMDFLINSSS- 944

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477
             G++     LD ++   Y L V A+D+G   +S T+ + I++ D N+  P F  A Y  S
Sbjct: 945  -GVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDETPTFFPAVYNVS 1003

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            V ED P    V+ ++ TD+DVG+NA+++Y ++         + D +F +  +   + T  
Sbjct: 1004 VSEDVPREFRVVWLNCTDNDVGLNAELSYFITG-------GNVDGKFSVGYRDAVVRTVV 1056

Query: 538  LLDRETMSGYLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
             LDRET + Y+L + A D G      + T  V ++V+DVNDN P+F Q  Y A++ ED  
Sbjct: 1057 GLDRETTAAYMLILEAIDNGPVGKRHTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIP 1116

Query: 596  VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI-RTNKALDRESVATHD 654
             G S+ Q+ ATDAD G  GR+ Y +        +F I  ++G++ R  + LDRE  ++H 
Sbjct: 1117 EGHSILQLKATDADEGEFGRVWYRI-LHGNHGNNFRIHVSNGLLMRGPRPLDRERNSSHV 1175

Query: 655  LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF-ESDCLTFYISENSPIGTTIGEIRAHD 713
            L   A +    P  S+V V + +EDIND  PVF +       + E + IGT++  ++A D
Sbjct: 1176 LIVEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAGIGTSVIVVQATD 1235

Query: 714  PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP 773
             D G   +V+Y I  G +   F ++   G     ++T+  LDYE+       V      P
Sbjct: 1236 RDSGDGGLVNYRILSGAE-GKFEIDESTGL----IITVNYLDYETKTSYMMNVSATDQAP 1290

Query: 774  LWNDVRVEILVTDVN--DNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRI 831
             +N     + +T +N  D A    +        ++        RV AY  D  +++ YR 
Sbjct: 1291 PFNQGFCSVYITLLNELDEAVQFSNASYEAAILENLALGTEIVRVQAYSIDNLNQITYRF 1350

Query: 832  ---LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLIT 888
                S     L  ++  TG +T+   ++       T+ V   DG  ++ + +++ + ++ 
Sbjct: 1351 DAYTSTQAKALFKIDAITGVITVQGLVDREKGDFYTLTVVADDGGPKVDSTVKVYITVLD 1410

Query: 889  E 889
            E
Sbjct: 1411 E 1411



 Score =  295 bits (725), Expect = 9e-78
 Identities = 238/779 (30%), Positives = 370/779 (47%), Gaps = 71/779 (9%)

Query: 15   DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
            D ND  P F       SV E A  GT +  + A D D+  N ++EY I  + A     +D
Sbjct: 2166 DINDSRPEFLNPIQTVSVLESAEPGTVIANITAIDHDL--NPKLEYHIVGIVAK----DD 2219

Query: 75   AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSST- 133
                        +D F ++  +G+++ ++ ++RE VA Y V +   D AS + +R  S  
Sbjct: 2220 TDRLVPNQ----EDAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNASDLPERSVSVP 2275

Query: 134  -ATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS-VTDNPVIAKIKATDADVGANSAIRYAI 191
             A + VN++D NDN PQF     T  ++  +   T    +  + A D D G N  + Y +
Sbjct: 2276 NAKLTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGLNGLVTYTL 2335

Query: 192  IG----GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            +     G  Q++   DS +G V   +T+DYE+V      +RA D GSP R+    + + I
Sbjct: 2336 LDLVPPGYVQLE---DSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEI 2392

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
             D+NDN P F    +QE+V E+VP+G  I+ V A DAD G  A + Y++      G+ + 
Sbjct: 2393 VDINDNNPIFDQPSYQEAVFEDVPVGTIILTVTATDADSGNFALIEYSL------GDGES 2446

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG-GDPP---RSATATXXXXXXXXXXXX 363
               I+P +G +Y    LDRE +  Y L   A D  GD     R  +              
Sbjct: 2447 KFAINPTTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCR 2506

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRG 421
              F   Q+   + E+EP GT V+T+ ATD DE  +  L Y + G      F +   +  G
Sbjct: 2507 PQFSKPQFSTSVYENEPAGTSVITMMATDQDEGPNGELTYSLEGPGVEA-FHVDMDS--G 2563

Query: 422  LITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAP--YTAS 477
            L+T  +PL  +   ++ LTV ATD G      T M+ + + D N+  PVF   P      
Sbjct: 2564 LVTTQRPL--QSYEKFSLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILH 2621

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            + E+ P+ + V  V ATD D G+N  + YS      N       + F+I+P +G I T +
Sbjct: 2622 IREEIPLRSNVYEVYATDKDEGLNGAVRYSFLKTAGN----RDWEFFIIDPISGLIQTAQ 2677

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTD-VEISVVDVNDNEPVF------KQQLYTANI 590
             LDRE+ + Y L + A D G P   +T   +++++ D++DNEP+F        Q     +
Sbjct: 2678 RLDRESQAVYSLILVASDLGQPVPYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTV 2737

Query: 591  MEDALVGTSVSQV-GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD--R 647
             E +  GT V  V GA DAD G N  ++Y +     EE +F + P  G +   + LD  R
Sbjct: 2738 PEHSPRGTLVGNVTGAVDADEGPNAIVYYFI-AAGNEEKNFHLQP-DGCLLVLRDLDRER 2795

Query: 648  ESVATHDLKAVAIDGGTPPQ--SSTV---------IVHIKIEDINDSPPVFESDCLTFYI 696
            E++ +  +KA +    TPP+  S T+          V + +EDIND PP F     T  +
Sbjct: 2796 EAIFSFIVKASSNRSWTPPRGPSPTLDLVADLTLQEVRVVLEDINDQPPRFTKAEYTAGV 2855

Query: 697  SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755
            + ++ +G+ + ++ A D D G N++V YSI      + F        D  ++ TM  +D
Sbjct: 2856 ATDAKVGSELIQVLALDADIGNNSLVFYSILA---IHYFRALANDSEDVGQVFTMGSMD 2911



 Score =  287 bits (703), Expect = 4e-75
 Identities = 247/820 (30%), Positives = 373/820 (45%), Gaps = 85/820 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I VLD ND+ PV        ++ E +   + V  + A+D D G NA + + I   TA   
Sbjct: 1839 IRVLDINDNDPVLLNLPMNITISENSPVSSFVAHVLASDADSGCNARLTFNI---TAG-- 1893

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N E A              F I+  +G +     LDRE++  Y + +   D  +P + R+
Sbjct: 1894 NRERA--------------FFINATTGIVTVNRPLDRERIPEYKLTISVKD--NPENPRI 1937

Query: 131  SSTA--TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIA---KIKATDADVGANS 185
            +      + + + D+NDN+P F++ TY   V E+ S    P+      I A DAD    +
Sbjct: 1938 ARRDYDLLLIFLSDENDNHPLFTKSTYQAEVMEN-SPAGTPLTVLNGPILALDADQDIYA 1996

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVK--TLDYEQVRS--YRLVIRAQDGGSPSRSNTT 241
             + Y ++G  + + F I+S +G V++     +D E        L++ A+D G    ++T 
Sbjct: 1997 VVTYQLLGAQSGL-FDINSSTGVVTVRSGVIIDREAFSPPILELLLLAEDIGL--LNSTA 2053

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
             LLI I D NDN P F  +     + EN P G+S+++V A D D G+N EL Y +     
Sbjct: 2054 HLLITILDDNDNRPTFSPATLTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQ 2113

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
               +   +T   R G    +  +DRE Q  Y+L V ATD G  P S TA           
Sbjct: 2114 DRFLIHLVTGVIRVG----NATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDIND 2169

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITG-----------GNTRG 410
                F+     V + E   PGT +  +TA D D + +L Y I G            N   
Sbjct: 2170 SRPEFLNPIQTVSVLESAEPGTVIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQED 2229

Query: 411  RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG----RS---DTAMVQINITDAN 463
             F++    G   + V  P++ +    Y +T+S  D+      RS     A + +N+ D N
Sbjct: 2230 AFAVNINTGS--VMVKSPMNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNVLDVN 2287

Query: 464  NYAPVFEN---APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520
            +  P F+      Y   + E A  GTT++ V+A D D G+N  +TY+L   +    V   
Sbjct: 2288 DNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGLNGLVTYTLLDLVPPGYVQLE 2347

Query: 521  DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580
            D         G +  N+ +D E +     TV A D G P  +    V + +VD+NDN P+
Sbjct: 2348 DSS------AGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPI 2401

Query: 581  FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640
            F Q  Y   + ED  VGT +  V ATDAD G    I Y L      E  F I+P +G I 
Sbjct: 2402 FDQPSYQEAVFEDVPVGTIILTVTATDADSGNFALIEYSLGDG---ESKFAINPTTGDIY 2458

Query: 641  TNKALDRESVATHDLKAVAIDG----GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696
               +LDRE    + L A+A D      +  + ++V V I++ D+ND  P F     +  +
Sbjct: 2459 VLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSV 2518

Query: 697  SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756
             EN P GT++  + A D DEGPN  + YS++G     +F ++   G     LVT      
Sbjct: 2519 YENEPAGTSVITMMATDQDEGPNGELTYSLEG-PGVEAFHVDMDSG-----LVT-TQRPL 2571

Query: 757  ESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPV 793
            +S  +K+ L + A     PPLW    + + V DVNDN PV
Sbjct: 2572 QS-YEKFSLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPV 2610



 Score =  273 bits (669), Expect = 5e-71
 Identities = 250/876 (28%), Positives = 390/876 (44%), Gaps = 71/876 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V D ND++P F  Q Y   + E    GT +  + ATD D+G    V Y+ +       
Sbjct: 120 IQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQ------- 172

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            P                 F ID   G +     LD E    Y + V ATDQ    +  L
Sbjct: 173 -PPS-------------QFFAIDSARGIVTVIRELDYETTQAYQLTVNATDQDK--TRPL 216

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           S+ A + + I D  D  P F    Y+ ++ E         +  I A D D G    I Y 
Sbjct: 217 STLANLAIIITDVQDMDPIFINLPYSTNIYEHSP--PGTTVRIITAIDQDKGRPRGIGYT 274

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQ-VRSYRLVIRAQ-----DGGSPSRSN-TTQL 243
           I+ GNT   F++D +SG ++L   LD E  + S+  ++  +     D  +PS +  TT  
Sbjct: 275 IVSGNTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTF 334

Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSI-VRVQAYDADE--GVNAELTYTMTDKD 300
            I + D+NDNAP F +S +  +++E   +G+++ + +Q  D DE  G+N+     +   +
Sbjct: 335 NILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDENLGLNSMFEVYLVGNN 394

Query: 301 YTGNVDLPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
               +  P ++  ++   +  +  LD ET  +Y   + A +   P     A         
Sbjct: 395 SHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESV-PDHVGYAKVKITLINE 453

Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG 419
                 F    Y + L E+   GT V+T+ ATD D            +   RFS+    G
Sbjct: 454 NDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFFSDDPDRFSLDKDTG 513

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479
             LI +   LD++  +R+ LT+ A D GG   T  V+IN+ D N+  P F+   Y  ++ 
Sbjct: 514 --LIMLIARLDYELIQRFTLTIIARDGGGEETTGRVRINVLDVNDNVPTFQKDAYVGALR 571

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           E+ P  T ++ + ATD D   N QITYS+   +S  A   +     +    G I+ ++ L
Sbjct: 572 ENEPSVTQLVRLRATDEDSPPNNQITYSI---VSASAFGSY-FDISLYEGYGVISVSRPL 627

Query: 540 DRETMSGYL--LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
           D E +S  L  LTV A D G P L+ T  V I V D NDN P F +  Y  +++E+ + G
Sbjct: 628 DYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAG 687

Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGS--FVIDPASGVIRTNKALDRESVATHDL 655
            +V  + ATD D     R + +       EGS  F I+  SG I T   LDRE+ + + L
Sbjct: 688 ATVLFLNATDLD---RSREYGQESIIYSLEGSTQFRINARSGEITTTSLLDRETKSEYIL 744

Query: 656 KAVAIDGGTPPQSSTVI--VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713
              A+DGG      T I  V+I + DIND+ P ++       + E +P  + +  + A D
Sbjct: 745 IVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVD 804

Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP--------RKKYEL 765
           PD G N  + YSI+    +  +SL +  G  +    T   LD E+P        RK    
Sbjct: 805 PDLGENGTLVYSIQ--PPNKFYSLNSTTGKIR---TTHAMLDRENPDPHEAELMRKIVVS 859

Query: 766 VIRAASPPL--WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD 822
           V     PPL   +   V + + D+NDN P  ++   +     +  P G    +V A D D
Sbjct: 860 VTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFV-AEVLEGIPAGVSIYQVVAIDLD 918

Query: 823 --VTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
             +   + YR+  G      L+N ++G +  + +L+
Sbjct: 919 EGLNGLVSYRMPVGMPRMDFLINSSSGVVVTTTELD 954



 Score =  269 bits (659), Expect = 9e-70
 Identities = 254/873 (29%), Positives = 397/873 (45%), Gaps = 85/873 (9%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F ++  +G +  R  LDRE  + +TV    +D    +      T  +++ + D NDN P 
Sbjct: 78  FAVEPDTGVVWLRQPLDRETKSEFTVEFSVSDHQGVI------TRKVNIQVGDVNDNAPT 131

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209
           F  + Y+V + E+  V   P+   + ATD D+GA  ++ Y+         F+IDS  G V
Sbjct: 132 FHNQPYSVRIPENTPV-GTPIFI-VNATDPDLGAGGSVLYSF--QPPSQFFAIDSARGIV 187

Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT-TQLLINIRDVNDNAPRFYTSLFQESVSE 268
           ++++ LDYE  ++Y+L + A D       +T   L I I DV D  P F    +  ++ E
Sbjct: 188 TVIRELDYETTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYE 247

Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328
           + P G ++  + A D D+G    + YT+     +GN +    +D  SG +  +G LDRE 
Sbjct: 248 HSPPGTTVRIITAIDQDKGRPRGIGYTIV----SGNTNSIFALDYISGVLTLNGLLDREN 303

Query: 329 ---QAKYQLLVTATDGGD--PPRSATATXXXXXXXXXXXXXX--FMPGQYEVELAEDEPP 381
                 + L V  T+  D   P  AT T                F   +Y V + E    
Sbjct: 304 PLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQV 363

Query: 382 GTPV-VTLTATDADEDNRLH--YEI-TGGNTRGRFSI--TSQNGRG--LITVAQPLDFKQ 433
           G  + + +   D DE+  L+  +E+   GN    F I  TS  G+    I VA PLD++ 
Sbjct: 364 GFALPLFIQVVDKDENLGLNSMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYET 423

Query: 434 ERRYVLTVSATDS-GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492
             RY   + A +S       A V+I + + N+  P+F    Y  S++E+  +GT+VL V 
Sbjct: 424 VDRYDFDLFANESVPDHVGYAKVKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVL 483

Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552
           ATD+D G   +++Y  S +           +F ++  TG I     LD E +  + LT+ 
Sbjct: 484 ATDNDAGTFGEVSYFFSDD---------PDRFSLDKDTGLIMLIARLDYELIQRFTLTII 534

Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612
           ARDGG      T  V I+V+DVNDN P F++  Y   + E+    T + ++ ATD D   
Sbjct: 535 ARDGG--GEETTGRVRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPP 592

Query: 613 NGRIHYELDPKDREEGSFVID--PASGVIRTNKALDRESVATH--DLKAVAIDGGTPPQS 668
           N +I Y +         F I      GVI  ++ LD E ++     L  +A+D G PP +
Sbjct: 593 NNQITYSIVSASAFGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLN 652

Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE----GPNAVVHY 724
           STV V I++ D ND+PP F        + EN   G T+  + A D D     G  +++ Y
Sbjct: 653 STVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESII-Y 711

Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR----- 779
           S++G   S  F +  R G    E+ T   LD E+ + +Y L++RA    + ++ +     
Sbjct: 712 SLEG---STQFRINARSG----EITTTSLLDRET-KSEYILIVRAVDGGVGHNQKTGIAT 763

Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNNA 837
           V I + D+NDN P  KD     N  +   P      V A D D+ +   L Y I   N  
Sbjct: 764 VNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQPPN-- 821

Query: 838 NLILLNETTGSM-TLSPQLNTNVPK------LATMEVSVTD-GVNEIKAMMQLSVRLITE 889
               LN TTG + T    L+   P       +  + VSVTD G   +KA    +V     
Sbjct: 822 KFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATV----- 876

Query: 890 EMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAA 922
              +N + +  ND T +    P +   ++G+ A
Sbjct: 877 --FVNLLDLNDNDPTFQNL--PFVAEVLEGIPA 905



 Score =  220 bits (538), Expect = 4e-55
 Identities = 193/650 (29%), Positives = 279/650 (42%), Gaps = 49/650 (7%)

Query: 167 DNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLV 226
           D PV + +    A    N  + + + G      F+++  +G V L + LD E    + + 
Sbjct: 45  DTPVGSSVTQLLAQDMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETKSEFTVE 104

Query: 227 IRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE 286
               D        T ++ I + DVNDNAP F+   +   + EN P+G  I  V A D D 
Sbjct: 105 FSVSDHQGVI---TRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNATDPDL 161

Query: 287 GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-P 345
           G    + Y+               ID   G V    +LD ET   YQL V ATD     P
Sbjct: 162 GAGGSVLYSFQPPSQF------FAIDSARGIVTVIRELDYETTQAYQLTVNATDQDKTRP 215

Query: 346 RSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI 403
            S  A               F+   Y   + E  PPGT V  +TA D D+     + Y I
Sbjct: 216 LSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRIITAIDQDKGRPRGIGYTI 275

Query: 404 TGGNTRGRFSITSQNG----RGLITVAQPLDFKQERRYVLTVSAT---DSGGRSD---TA 453
             GNT   F++   +G     GL+    PL       ++LTV  T   D    SD   T 
Sbjct: 276 VSGNTNSIFALDYISGVLTLNGLLDRENPL---YSHGFILTVKGTELNDDRTPSDATVTT 332

Query: 454 MVQINITDANNYAPVFENAPYTASVFEDAPIGTTV-LVVSATDSDVGINAQITYSLSSEI 512
              I + D N+ AP F ++ Y+ ++ E A +G  + L +   D D  +       L+S  
Sbjct: 333 TFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDENL------GLNSMF 386

Query: 513 SNEAVAHHDQQFVINPQTG------AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566
               V ++   F+I+P +        I     LD ET+  Y   + A +  VP       
Sbjct: 387 EVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANE-SVPDHVGYAK 445

Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDR 625
           V+I++++ NDN P+F Q LY  ++ E+  VGTSV  V ATD D G  G + Y   D  DR
Sbjct: 446 VKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFFSDDPDR 505

Query: 626 EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685
               F +D  +G+I     LD E +    L  +A DGG   + +T  V I + D+ND+ P
Sbjct: 506 ----FSLDKDTGLIMLIARLDYELIQRFTLTIIARDGG--GEETTGRVRINVLDVNDNVP 559

Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS-FSLETRQGSD 744
            F+ D     + EN P  T +  +RA D D  PN  + YSI       S F +   +G  
Sbjct: 560 TFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYG 619

Query: 745 KAELVTMVDLDYESPRKKYELVIR--AASPPLWNDVRVEILVTDVNDNAP 792
              +   +D +  S    Y  V+   A +PPL + V V I V D NDN P
Sbjct: 620 VISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPP 669



 Score =  185 bits (450), Expect = 2e-44
 Identities = 167/566 (29%), Positives = 258/566 (45%), Gaps = 60/566 (10%)

Query: 257 FYTSLFQES---VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313
           F+T+ F ++   +SE+ P+G S+ ++ A D D   N  L + ++ ++          ++P
Sbjct: 30  FFTNHFFDTYLLISEDTPVGSSVTQLLAQDMD---NDPLVFGVSGEE----ASRFFAVEP 82

Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373
            +G V+    LDRET++++ +  + +   D     T                F    Y V
Sbjct: 83  DTGVVWLRQPLDRETKSEFTVEFSVS---DHQGVITRKVNIQVGDVNDNAPTFHNQPYSV 139

Query: 374 ELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ-----NGRGLITVAQP 428
            + E+ P GTP+  + ATD D          GG+    F   SQ     + RG++TV + 
Sbjct: 140 RIPENTPVGTPIFIVNATDPDLG-------AGGSVLYSFQPPSQFFAIDSARGIVTVIRE 192

Query: 429 LDFKQERRYVLTVSATDSGGR---SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
           LD++  + Y LTV+ATD       S  A + I ITD  +  P+F N PY+ +++E +P G
Sbjct: 193 LDYETTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPG 252

Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET-- 543
           TTV +++A D D G    I Y++ S  +N         F ++  +G +T N LLDRE   
Sbjct: 253 TTVRIITAIDQDKGRPRGIGYTIVSGNTNSI-------FALDYISGVLTLNGLLDRENPL 305

Query: 544 -MSGYLLTVTA---RDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
              G++LTV      D   PS  + TT   I V+D+NDN P F    Y+  I E A VG 
Sbjct: 306 YSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGF 365

Query: 599 SVS---QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV------IRTNKALDRES 649
           ++    QV   D ++GLN    +E+         F+I P S        IR    LD E+
Sbjct: 366 ALPLFIQVVDKDENLGLNSM--FEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYET 423

Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
           V  +D    A +   P       V I + + ND+ P+F        + EN  +GT++  +
Sbjct: 424 VDRYDFDLFA-NESVPDHVGYAKVKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTV 482

Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
            A D D G    V Y     DD + FSL+     D   ++ +  LDYE  ++    +I  
Sbjct: 483 LATDNDAGTFGEVSYFF--SDDPDRFSLD----KDTGLIMLIARLDYELIQRFTLTIIAR 536

Query: 770 ASPPLWNDVRVEILVTDVNDNAPVMK 795
                    RV I V DVNDN P  +
Sbjct: 537 DGGGEETTGRVRINVLDVNDNVPTFQ 562



 Score =  175 bits (425), Expect = 2e-41
 Identities = 143/514 (27%), Positives = 233/514 (45%), Gaps = 27/514 (5%)

Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434
           ++ED P G+ V  L A D D D  L + ++G      F++    G  ++ + QPLD + +
Sbjct: 42  ISEDTPVGSSVTQLLAQDMDNDP-LVFGVSGEEASRFFAVEPDTG--VVWLRQPLDRETK 98

Query: 435 RRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494
             + +  S +D  G   T  V I + D N+ AP F N PY+  + E+ P+GT + +V+AT
Sbjct: 99  SEFTVEFSVSDHQGVI-TRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNAT 157

Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554
           D D+G    + YS              Q F I+   G +T  + LD ET   Y LTV A 
Sbjct: 158 DPDLGAGGSVLYSFQPP---------SQFFAIDSARGIVTVIRELDYETTQAYQLTVNAT 208

Query: 555 D-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613
           D      LS   ++ I + DV D +P+F    Y+ NI E +  GT+V  + A D D G  
Sbjct: 209 DQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRIITAIDQDKGRP 268

Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES-VATH----DLKAVAIDGGTPPQS 668
             I Y +         F +D  SGV+  N  LDRE+ + +H     +K   ++    P  
Sbjct: 269 RGIGYTI-VSGNTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSD 327

Query: 669 STVIV--HIKIEDINDSPPVFESDCLTFYISENSPIGTTIG-EIRAHDPDE--GPNAVVH 723
           +TV    +I + DIND+ P F S   +  I+E + +G  +   I+  D DE  G N++  
Sbjct: 328 ATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDENLGLNSMFE 387

Query: 724 YSIKGGDDSNSFSLETR-QGSDKAELVTMVDLDYES-PRKKYELVIRAASPPLWNDVRVE 781
             + G +  +     T  QG     +   + LDYE+  R  ++L    + P      +V+
Sbjct: 388 VYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAKVK 447

Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLIL 841
           I + + NDN P+        + Y++         V A D D     +      ++ +   
Sbjct: 448 ITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFFSDDPDRFS 507

Query: 842 LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE 875
           L++ TG + L  +L+  + +  T+ +   DG  E
Sbjct: 508 LDKDTGLIMLIARLDYELIQRFTLTIIARDGGGE 541



 Score = 89.4 bits (212), Expect = 1e-15
 Identities = 82/304 (26%), Positives = 131/304 (43%), Gaps = 35/304 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEA--SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68
            + V+D ND+ PVF          +RE     + V  + ATD+D G N  V Y+  L TA 
Sbjct: 2599 VEVIDVNDNRPVFVRPPNGTILHIREEIPLRSNVYEVYATDKDEGLNGAVRYSF-LKTAG 2657

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
              + E                F ID  SG + T   LDRE  A Y++++ A+D   PV  
Sbjct: 2658 NRDWE---------------FFIIDPISGLIQTAQRLDRESQAVYSLILVASDLGQPVPY 2702

Query: 129  RLSSTATIHVNIIDDNDNY---PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
                   + +  IDDN+     P      Y +    + S     V     A DAD G N+
Sbjct: 2703 ETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNA 2762

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD--------GGSPSR 237
             + Y I  GN +  F +    G + +++ LD E+   +  +++A          G SP+ 
Sbjct: 2763 IVYYFIAAGNEEKNFHLQP-DGCLLVLRDLDREREAIFSFIVKASSNRSWTPPRGPSPTL 2821

Query: 238  SNTTQLLIN-----IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292
                 L +      + D+ND  PRF  + +   V+ +  +G  +++V A DAD G N+ +
Sbjct: 2822 DLVADLTLQEVRVVLEDINDQPPRFTKAEYTAGVATDAKVGSELIQVLALDADIGNNSLV 2881

Query: 293  TYTM 296
             Y++
Sbjct: 2882 FYSI 2885


>UniRef50_Q6V1P9 Cluster: Dachsous-2; n=9; Eutheria|Rep: Dachsous-2 -
            Homo sapiens (Human)
          Length = 2916

 Score =  352 bits (866), Expect = 7e-95
 Identities = 267/881 (30%), Positives = 420/881 (47%), Gaps = 57/881 (6%)

Query: 1    MSVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIG-KNAEVE 59
            +S+   +   I+V D NDHSP F+ +    SV E    GT V    A D D    N+ ++
Sbjct: 1033 LSLSSTVFLSIDVEDQNDHSPSFQDELIVISVEENVPIGTLVYVFNAKDDDGSFLNSRIQ 1092

Query: 60   YTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKA 119
            Y IE     T NP                 F I    G L+T + LDRE +    + V A
Sbjct: 1093 YYIESHNPGT-NP-----------------FLIHPSFGTLVTVSRLDRESIPTVILTVTA 1134

Query: 120  TDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA 179
            +DQA  V+DR   + T  + I+D ND+ P F        V ED++V    ++  I A D 
Sbjct: 1135 SDQAVNVTDRRLRSLTAQIVILDVNDHNPTFISFP-NAHVKEDVTV--GSLVHHITAHDP 1191

Query: 180  DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239
            D G N  + Y+I+ GN  M F +D  SG ++    LDYE    + L + A D G+P+ S+
Sbjct: 1192 DEGRNGKVTYSILSGNENMTFMLDESSGLLTTTCPLDYEMKTQHILTVLALDDGTPALSS 1251

Query: 240  TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
            +  L + + DVND AP F   L++ SV EN   G  + RV+A D D GVN++L + +   
Sbjct: 1252 SQTLTVTVLDVNDEAPVFKQHLYEASVKENQNPGEFVTRVEALDRDSGVNSKLQFEIMP- 1310

Query: 300  DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
                + +L   I+  +G V T+  LDRE Q  + L V   DGG P  S+T T        
Sbjct: 1311 --GASFEL-FEINSDTGEVVTTTILDREIQEVFTLRVLVRDGGFPSLSSTTTILCTVEDE 1367

Query: 360  XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQ 417
                  F+   Y++E+ E++ P   V T+ A+D D  N   + Y I  GNT   F+I   
Sbjct: 1368 NDHAPEFIVSSYDIEVLENQEPEV-VYTVLASDMDAGNNRAVEYHIIDGNTDECFTINEM 1426

Query: 418  NGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYT 475
            +G   ++  + LD +Q   + L +  +D G   RS    +Q+ + DAN+++P F    Y 
Sbjct: 1427 SGE--LSTTRALDREQISNFTLVILCSDLGDPPRSSVIHLQVRVLDANDHSPSFPTLYYQ 1484

Query: 476  ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
            +SV EDA +GT VLV+SA D D G+N Q  Y L+ E S          F I+P +G + T
Sbjct: 1485 SSVREDAEVGTVVLVLSAVDKDEGLNGQTEYFLTDEASG--------AFTIDPMSGTLKT 1536

Query: 536  NKLLDRETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
            +  LDRE  S +  +  ARD  +  S S T  +++ V DVNDN+PV +Q  +   +  ++
Sbjct: 1537 SNTLDREARSQHTFSAVARDCSIQGSRSTTVIIKVYVTDVNDNDPVLEQNPFDVFLSPES 1596

Query: 595  LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654
                +   V A D D+G NG + +        +  F ID  +G I+  +    E      
Sbjct: 1597 PTNQTTVIVRADDLDLGPNGTVVFSF---AETQSMFSIDKYTGEIQFQQNPSSEYFPIW- 1652

Query: 655  LKAVAIDGGTPPQSST--VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
            L+    D G P +++T  +++H++ ED+  S   F        ++EN   GT+I  ++A 
Sbjct: 1653 LQLKVTDQGIPARTTTGLLVIHMEGEDVKIS---FSHHLYKGLVTENCEAGTSIVTVKAF 1709

Query: 713  DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP 772
             PD   ++ + YSI  G++    SL ++ G    +    +D +    R + +L++ A S 
Sbjct: 1710 APDSIQDS-MKYSIFSGNEDGVLSLCSKSGQLTVKEPKFLDFEV---RNEVQLIVLAESS 1765

Query: 773  PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYR 830
                  +V +L+ D NDN+P  +      +  +         +V A D D  +   ++Y 
Sbjct: 1766 GHRAYCKVAVLIQDENDNSPCFEQSIYQASVSESQLYNAHVIQVFATDLDSGLNGLIEYS 1825

Query: 831  ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            ILSGN      ++  +G +T    L+  +    ++ V  TD
Sbjct: 1826 ILSGNQEEAFQIDALSGVITTKAILDYELTSSYSLIVQATD 1866



 Score =  333 bits (819), Expect = 3e-89
 Identities = 264/884 (29%), Positives = 423/884 (47%), Gaps = 68/884 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + VLD ND +PVF+   YEASV+E  + G  V  ++A D+D G N+++++  E++   + 
Sbjct: 1257 VTVLDVNDEAPVFKQHLYEASVKENQNPGEFVTRVEALDRDSGVNSKLQF--EIMPGASF 1314

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                             ++F I+  +G ++T   LDRE    +T+ V   D   P    L
Sbjct: 1315 -----------------ELFEINSDTGEVVTTTILDREIQEVFTLRVLVRDGGFP---SL 1354

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            SST TI   + D+ND+ P+F   +Y + V E+    +  V+  + A+D D G N A+ Y 
Sbjct: 1355 SSTTTILCTVEDENDHAPEFIVSSYDIEVLEN---QEPEVVYTVLASDMDAGNNRAVEYH 1411

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            II GNT   F+I+ +SG++S  + LD EQ+ ++ LVI   D G P RS+   L + + D 
Sbjct: 1412 IIDGNTDECFTINEMSGELSTTRALDREQISNFTLVILCSDLGDPPRSSVIHLQVRVLDA 1471

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            ND++P F T  +Q SV E+  +G  ++ + A D DEG+N +  Y +TD + +G      T
Sbjct: 1472 NDHSPSFPTLYYQSSVREDAEVGTVVLVLSAVDKDEGLNGQTEYFLTD-EASG----AFT 1526

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPPRSATATXXXXXXXXXXXXXXFMPG 369
            IDP SG + TS  LDRE ++++     A D      RS T                    
Sbjct: 1527 IDPMSGTLKTSNTLDREARSQHTFSAVARDCSIQGSRSTTVIIKVYVTDVNDNDPVLEQN 1586

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
             ++V L+ + P     V + A D D         +   T+  FSI    G       Q  
Sbjct: 1587 PFDVFLSPESPTNQTTVIVRADDLDLGPNGTVVFSFAETQSMFSIDKYTGE---IQFQQN 1643

Query: 430  DFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
               +     L +  TD G   R+ T ++ I++ +  +    F +  Y   V E+   GT+
Sbjct: 1644 PSSEYFPIWLQLKVTDQGIPARTTTGLLVIHM-EGEDVKISFSHHLYKGLVTENCEAGTS 1702

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN--KLLDRETMS 545
            ++ V A   D  I   + YS+ S   NE     D    +  ++G +T    K LD E  +
Sbjct: 1703 IVTVKAFAPD-SIQDSMKYSIFS--GNE-----DGVLSLCSKSGQLTVKEPKFLDFEVRN 1754

Query: 546  GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
               L V A   G  +      V + + D NDN P F+Q +Y A++ E  L    V QV A
Sbjct: 1755 EVQLIVLAESSGHRAY---CKVAVLIQDENDNSPCFEQSIYQASVSESQLYNAHVIQVFA 1811

Query: 606  TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
            TD D GLNG I Y +   ++EE +F ID  SGVI T   LD E  +++ L   A D G P
Sbjct: 1812 TDLDSGLNGLIEYSILSGNQEE-AFQIDALSGVITTKAILDYELTSSYSLIVQATDKGMP 1870

Query: 666  PQSSTVIVHIKIEDINDSPPVF-ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
              S+T ++ +++ DIND+ P F  S+ +   I+E+S  G  +  +  HD D   +A +  
Sbjct: 1871 RLSNTTVIKVQVTDINDNAPAFLPSEAVE--ITEDSLPGVIVTHVSVHDVDLN-SAFIFS 1927

Query: 725  SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILV 784
              K  +    F+++   G     +V +  LD+E    +YEL+I+ +    + +  + + V
Sbjct: 1928 FAKESNPGTKFAIDQNTG----VVVLVKTLDFEE-MTEYELLIQISDSVHYTEGALVVRV 1982

Query: 785  TDVNDNAPVM-KDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLILL 842
             DVNDN PV  +DF  +     +  PVG     + A D +  + + YRILS +      +
Sbjct: 1983 LDVNDNPPVFSQDFYQV--TVPESIPVGYSVLTLSATDLESNENISYRILSSSKE--FSI 2038

Query: 843  NETTGSM-TLSPQLNTNVPKLATMEVSVTDGVN-EIKAMMQLSV 884
            +   G++ T+SP L  +        V  +DG N +++A+  + +
Sbjct: 2039 DPKNGTIFTISPVLLLDTISTTQFLVEASDGGNPDLRALTLVEI 2082



 Score =  306 bits (751), Expect = 6e-81
 Identities = 270/886 (30%), Positives = 405/886 (45%), Gaps = 79/886 (8%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            IH Q+ VLD NDHSP F    Y++SVRE A  GT VL L A D+D G N + EY +    
Sbjct: 1462 IHLQVRVLDANDHSPSFPTLYYQSSVREDAEVGTVVLVLSAVDKDEGLNGQTEYFLT--- 1518

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
                  ++A              F ID  SG L T  +LDRE  +++T    A D +  +
Sbjct: 1519 ------DEASGA-----------FTIDPMSGTLKTSNTLDREARSQHTFSAVARDCS--I 1559

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
                S+T  I V + D NDN P   +  + V +  +       VI  ++A D D+G N  
Sbjct: 1560 QGSRSTTVIIKVYVTDVNDNDPVLEQNPFDVFLSPESPTNQTTVI--VRADDLDLGPNGT 1617

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            + ++     TQ  FSID  +G++   +    E    + L ++  D G P+R+ T  L+I+
Sbjct: 1618 VVFSF--AETQSMFSIDKYTGEIQFQQNPSSEYFPIW-LQLKVTDQGIPARTTTGLLVIH 1674

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            +    D    F   L++  V+EN   G SIV V+A+ A + +   + Y++    ++GN D
Sbjct: 1675 MEG-EDVKISFSHHLYKGLVTENCEAGTSIVTVKAF-APDSIQDSMKYSI----FSGNED 1728

Query: 307  LPITIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
              +++  +SG +       LD E + + QL+V A   G     A                
Sbjct: 1729 GVLSLCSKSGQLTVKEPKFLDFEVRNEVQLIVLAESSG---HRAYCKVAVLIQDENDNSP 1785

Query: 365  XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGL 422
             F    Y+  ++E +     V+ + ATD D   +  + Y I  GN    F I + +G  +
Sbjct: 1786 CFEQSIYQASVSESQLYNAHVIQVFATDLDSGLNGLIEYSILSGNQEEAFQIDALSG--V 1843

Query: 423  ITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
            IT    LD++    Y L V ATD G    S+T ++++ +TD N+ AP F  +     + E
Sbjct: 1844 ITTKAILDYELTSSYSLIVQATDKGMPRLSNTTVIKVQVTDINDNAPAFLPSE-AVEITE 1902

Query: 481  DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
            D+  G  V  VS  D D  +N+   +S + E SN        +F I+  TG +   K LD
Sbjct: 1903 DSLPGVIVTHVSVHDVD--LNSAFIFSFAKE-SNPGT-----KFAIDQNTGVVVLVKTLD 1954

Query: 541  RETMSGYLLTVTARDGGVPSLSDTTD-VEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
             E M+ Y L +   D    S+  T   + + V+DVNDN PVF Q  Y   + E   VG S
Sbjct: 1955 FEEMTEYELLIQISD----SVHYTEGALVVRVLDVNDNPPVFSQDFYQVTVPESIPVGYS 2010

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT-NKALDRESVATHDLKAV 658
            V  + ATD +   N  I Y +    +E   F IDP +G I T +  L  ++++T      
Sbjct: 2011 VLTLSATDLES--NENISYRILSSSKE---FSIDPKNGTIFTISPVLLLDTISTTQFLVE 2065

Query: 659  AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-EG 717
            A DGG P   +  +V I IED+N+  P F        +SE++ +G+T+      D D   
Sbjct: 2066 ASDGGNPDLRALTLVEIGIEDMNNYAPEFTVKSYNLSLSEDALVGSTLVTFSNIDHDWTR 2125

Query: 718  PNAVVHYSIKGGDDSNSFSLETRQGSDK------AELVTMVDLDYESPRKKYELVIRAAS 771
             N  V YSI  G+  N+F +ET+    +        LV +  LD E+    +ELVI A+ 
Sbjct: 2126 ENTYVEYSIISGNSQNNFHVETKFFHSEYPYKQVGYLVLLHSLDREASAS-HELVILASD 2184

Query: 772  ---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADVTDKL 827
               PPL +   + I V DVNDN P          + K+  P+G     V A D D     
Sbjct: 2185 SGCPPLSSTAVISIQVLDVNDNPPNFSSLSY-HTHVKESTPLGSHITVVSANDRDTGSHA 2243

Query: 828  Q--YRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            +  Y I+SGN      L E TG + L   L+       T+ V  +D
Sbjct: 2244 EIIYNIISGNEKGHFYLEENTGVLYLIKPLDYEKMTKFTLTVQASD 2289



 Score =  304 bits (746), Expect = 2e-80
 Identities = 246/804 (30%), Positives = 376/804 (46%), Gaps = 65/804 (8%)

Query: 11   INVLDCNDHSPVFEM----QQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            ++V D ND+ P F      ++    V EG      V T+ A D D G NAEV Y++    
Sbjct: 827  VSVTDINDNRPFFPQCLPGKELHVKVLEGQPVNMLVTTVFAKDPDEGNNAEVTYSV---- 882

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
                + ED+            D F+ID  +G + T   L  +    Y + V ATDQ  P 
Sbjct: 883  ----SSEDSS-----------DHFKIDANNGEIRTTTILSYDYRPSYRMSVIATDQGVP- 926

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD-ADVGANS 185
               L   A +++ +I  +      S+    + + E++  T   +++ IK++D      N 
Sbjct: 927  --PLQGQAVVNIQVIPLSKGRAIMSQNIRHLIIPENLKPT--KIMSLIKSSDHLQQHYNG 982

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRL-VIRAQDGGSPSRSNTTQLL 244
             + ++I+  +    F IDS +GD+ L K LDYE    Y   VI      + S S+T  L 
Sbjct: 983  KLHFSIVADDKDGHFEIDSSTGDLFLSKELDYETTSHYLFRVITTDHSKNLSLSSTVFLS 1042

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG-VNAELTYTMTDKDYTG 303
            I++ D ND++P F   L   SV ENVPIG  +    A D D   +N+ + Y +   +   
Sbjct: 1043 IDVEDQNDHSPSFQDELIVISVEENVPIGTLVYVFNAKDDDGSFLNSRIQYYIESHNPGT 1102

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-----DPPRSATATXXXXXXX 358
            N   P  I P  G + T  +LDRE+     L VTA+D          RS TA        
Sbjct: 1103 N---PFLIHPSFGTLVTVSRLDRESIPTVILTVTASDQAVNVTDRRLRSLTAQIVILDVN 1159

Query: 359  XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITS 416
                     P  +   + ED   G+ V  +TA D DE  + ++ Y I  GN    F +  
Sbjct: 1160 DHNPTFISFPNAH---VKEDVTVGSLVHHITAHDPDEGRNGKVTYSILSGNENMTFMLDE 1216

Query: 417  QNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPY 474
             +  GL+T   PLD++ + +++LTV A D G    S +  + + + D N+ APVF+   Y
Sbjct: 1217 SS--GLLTTTCPLDYEMKTQHILTVLALDDGTPALSSSQTLTVTVLDVNDEAPVFKQHLY 1274

Query: 475  TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
             ASV E+   G  V  V A D D G+N+++ + +    S E        F IN  TG + 
Sbjct: 1275 EASVKENQNPGEFVTRVEALDRDSGVNSKLQFEIMPGASFEL-------FEINSDTGEVV 1327

Query: 535  TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
            T  +LDRE    + L V  RDGG PSLS TT +  +V D ND+ P F    Y   ++E+ 
Sbjct: 1328 TTTILDREIQEVFTLRVLVRDGGFPSLSSTTTILCTVEDENDHAPEFIVSSYDIEVLENQ 1387

Query: 595  LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654
                 V  V A+D D G N  + Y +   + +E  F I+  SG + T +ALDRE ++   
Sbjct: 1388 -EPEVVYTVLASDMDAGNNRAVEYHIIDGNTDE-CFTINEMSGELSTTRALDREQISNFT 1445

Query: 655  LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
            L  +  D G PP+SS + + +++ D ND  P F +      + E++ +GT +  + A D 
Sbjct: 1446 LVILCSDLGDPPRSSVIHLQVRVLDANDHSPSFPTLYYQSSVREDAEVGTVVLVLSAVDK 1505

Query: 715  DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES-PRKKYELVIRAAS-- 771
            DEG N    Y +   + S +F+++   G+    L T   LD E+  +  +  V R  S  
Sbjct: 1506 DEGLNGQTEYFLT-DEASGAFTIDPMSGT----LKTSNTLDREARSQHTFSAVARDCSIQ 1560

Query: 772  PPLWNDVRVEILVTDVNDNAPVMK 795
                  V +++ VTDVNDN PV++
Sbjct: 1561 GSRSTTVIIKVYVTDVNDNDPVLE 1584



 Score =  302 bits (742), Expect = 7e-80
 Identities = 230/753 (30%), Positives = 362/753 (48%), Gaps = 72/753 (9%)

Query: 13   VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72
            + D ND+SP FE   Y+ASV E       V+ + ATD D G N  +EY+I      + N 
Sbjct: 1777 IQDENDNSPCFEQSIYQASVSESQLYNAHVIQVFATDLDSGLNGLIEYSIL-----SGNQ 1831

Query: 73   EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132
            E+A              F+ID  SG + T+A LD E  + Y+++V+ATD+  P   RLS+
Sbjct: 1832 EEA--------------FQIDALSGVITTKAILDYELTSSYSLIVQATDKGMP---RLSN 1874

Query: 133  TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192
            T  I V + D NDN P F   +  V + ED       ++  +   D D+  NSA  ++  
Sbjct: 1875 TTVIKVQVTDINDNAPAFL-PSEAVEITED--SLPGVIVTHVSVHDVDL--NSAFIFSFA 1929

Query: 193  -GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251
               N   +F+ID  +G V LVKTLD+E++  Y L+I+  D    +      L++ + DVN
Sbjct: 1930 KESNPGTKFAIDQNTGVVVLVKTLDFEEMTEYELLIQISDSVHYTEG---ALVVRVLDVN 1986

Query: 252  DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311
            DN P F    +Q +V E++P+GYS++ + A D +   N       + K++        +I
Sbjct: 1987 DNPPVFSQDFYQVTVPESIPVGYSVLTLSATDLESNENISYRILSSSKEF--------SI 2038

Query: 312  DPRSGWVYT-SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            DP++G ++T S  L  +T +  Q LV A+DGG+P   A                 F    
Sbjct: 2039 DPKNGTIFTISPVLLLDTISTTQFLVEASDGGNPDLRALTLVEIGIEDMNNYAPEFTVKS 2098

Query: 371  YEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQ--------NG 419
            Y + L+ED   G+ +VT +  D D   E+  + Y I  GN++  F + ++          
Sbjct: 2099 YNLSLSEDALVGSTLVTFSNIDHDWTRENTYVEYSIISGNSQNNFHVETKFFHSEYPYKQ 2158

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477
             G + +   LD +    + L + A+DSG    S TA++ I + D N+  P F +  Y   
Sbjct: 2159 VGYLVLLHSLDREASASHELVILASDSGCPPLSSTAVISIQVLDVNDNPPNFSSLSYHTH 2218

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            V E  P+G+ + VVSA D D G +A+I Y++   IS     H    F +   TG +   K
Sbjct: 2219 VKESTPLGSHITVVSANDRDTGSHAEIIYNI---ISGNEKGH----FYLEENTGVLYLIK 2271

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
             LD E M+ + LTV A D      S    V +SV+D ND+ P F    ++  + E+  + 
Sbjct: 2272 PLDYEKMTKFTLTVQASDAEKKHFSFAV-VFVSVLDDNDHAPQFMFSSFSCIVPENLPIS 2330

Query: 598  TSVSQVGATDADVGLNGRIHYEL-DP------KDREEGSFVIDPASGVIRTNKALDRESV 650
            +++  + A D D G  G + Y +  P         +   F+IDP +G I   + LD E+ 
Sbjct: 2331 STICSINALDFDAGPYGELTYSIVSPCFLTHGMSYDHDLFLIDPLTGDIHAKQILDYENG 2390

Query: 651  ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710
              + L   A D G    +++++V + IE I++  P+F  D   F + E +     IG + 
Sbjct: 2391 NKYCLTVQAKDKG--DATASLVVWVDIEGIDEFEPIFTQDQYFFTLPEKNKDRQLIGRVE 2448

Query: 711  AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
            A D D G + V+ YS+  G  S  FS+    G+
Sbjct: 2449 ASDADAGIDGVILYSL--GTSSPFFSVNKTNGN 2479



 Score =  288 bits (706), Expect = 2e-75
 Identities = 227/755 (30%), Positives = 344/755 (45%), Gaps = 45/755 (5%)

Query: 136  IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195
            + V I D+NDN P F +  Y  SV E  S   N  + ++ ATD D G N  I Y+I+ GN
Sbjct: 1773 VAVLIQDENDNSPCFEQSIYQASVSE--SQLYNAHVIQVFATDLDSGLNGLIEYSILSGN 1830

Query: 196  TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP 255
             +  F ID+LSG ++    LDYE   SY L+++A D G P  SNTT + + + D+NDNAP
Sbjct: 1831 QEEAFQIDALSGVITTKAILDYELTSSYSLIVQATDKGMPRLSNTTVIKVQVTDINDNAP 1890

Query: 256  RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315
             F  S   E   +++P G  +  V  +D D  +N+   ++   +   G       ID  +
Sbjct: 1891 AFLPSEAVEITEDSLP-GVIVTHVSVHDVD--LNSAFIFSFAKESNPGT---KFAIDQNT 1944

Query: 316  GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375
            G V     LD E   +Y+LL+  +D       A                 F    Y+V +
Sbjct: 1945 GVVVLVKTLDFEEMTEYELLIQISDSVHYTEGALVVRVLDVNDNPPV---FSQDFYQVTV 2001

Query: 376  AEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435
             E  P G  V+TL+ATD + +  + Y I   +    FSI  +NG  + T++  L      
Sbjct: 2002 PESIPVGYSVLTLSATDLESNENISYRILSSSKE--FSIDPKNGT-IFTISPVLLLDTIS 2058

Query: 436  RYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
                 V A+D G     A+  V+I I D NNYAP F    Y  S+ EDA +G+T++  S 
Sbjct: 2059 TTQFLVEASDGGNPDLRALTLVEIGIEDMNNYAPEFTVKSYNLSLSEDALVGSTLVTFSN 2118

Query: 494  TDSD-VGINAQITYSLSSEISNEAVAHHDQQFVINP----QTGAITTNKLLDRETMSGYL 548
             D D    N  + YS+ S  S     H + +F  +     Q G +     LDRE  + + 
Sbjct: 2119 IDHDWTRENTYVEYSIISGNSQNNF-HVETKFFHSEYPYKQVGYLVLLHSLDREASASHE 2177

Query: 549  LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
            L + A D G P LS T  + I V+DVNDN P F    Y  ++ E   +G+ ++ V A D 
Sbjct: 2178 LVILASDSGCPPLSSTAVISIQVLDVNDNPPNFSSLSYHTHVKESTPLGSHITVVSANDR 2237

Query: 609  DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
            D G +  I Y +     E+G F ++  +GV+   K LD E +    L   A D       
Sbjct: 2238 DTGSHAEIIYNI-ISGNEKGHFYLEENTGVLYLIKPLDYEKMTKFTLTVQASD-AEKKHF 2295

Query: 669  STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
            S  +V + + D ND  P F     +  + EN PI +TI  I A D D GP   + YSI  
Sbjct: 2296 SFAVVFVSVLDDNDHAPQFMFSSFSCIVPENLPISSTICSINALDFDAGPYGELTYSIVS 2355

Query: 729  --------GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP-PLWNDVR 779
                      D + F ++   G   A+ +    LDYE+   KY L ++A         + 
Sbjct: 2356 PCFLTHGMSYDHDLFLIDPLTGDIHAKQI----LDYEN-GNKYCLTVQAKDKGDATASLV 2410

Query: 780  VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNA 837
            V + +  +++  P+    Q  F   +        GRV A DAD  +   + Y +  G ++
Sbjct: 2411 VWVDIEGIDEFEPIFTQDQYFFTLPEKNKDRQLIGRVEASDADAGIDGVILYSL--GTSS 2468

Query: 838  NLILLNETTGSMTL---SPQLNTNVPKLATMEVSV 869
                +N+T G++ L    P + + + K  T+E+ +
Sbjct: 2469 PFFSVNKTNGNIYLIRALPLIKSQLNKEDTLEMKI 2503



 Score =  258 bits (633), Expect = 1e-66
 Identities = 229/822 (27%), Positives = 367/822 (44%), Gaps = 65/822 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEY---------- 60
            + V D ND+SP F        V E       +  + A D D GKN ++ Y          
Sbjct: 680  VRVWDENDNSPTFLHDVLFLKVEESPVPQGVIGKITAIDMDSGKNGQLLYFLLSDGKFFK 739

Query: 61   ---------TIELVT----ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDR 107
                     TI ++T    A   +  D           V      +   G L+   +LDR
Sbjct: 740  MNPNTGPAGTIYVITWADGAAAFSGTDFAFSSDELQAFVLKSLFCELGEGELINWVALDR 799

Query: 108  EKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSE----KTYTVSVDEDI 163
            E    + + V  TD+ SP  +   +T  ++V++ D NDN P F +    K   V V E  
Sbjct: 800  EHRGHHEMTVLVTDRGSPPRN---ATMAVYVSVTDINDNRPFFPQCLPGKELHVKVLEGQ 856

Query: 164  SVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY 223
             V  N ++  + A D D G N+ + Y++   ++   F ID+ +G++     L Y+   SY
Sbjct: 857  PV--NMLVTTVFAKDPDEGNNAEVTYSVSSEDSSDHFKIDANNGEIRTTTILSYDYRPSY 914

Query: 224  RLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYD 283
            R+ + A D G P       + I +  ++        ++    + EN+     +  +++ D
Sbjct: 915  RMSVIATDQGVPPLQGQAVVNIQVIPLSKGRAIMSQNIRHLIIPENLKPTKIMSLIKSSD 974

Query: 284  -ADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD-G 341
               +  N +L +++   D  G+ +    ID  +G ++ S +LD ET + Y   V  TD  
Sbjct: 975  HLQQHYNGKLHFSIVADDKDGHFE----IDSSTGDLFLSKELDYETTSHYLFRVITTDHS 1030

Query: 342  GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE---DNR 398
             +   S+T                F      + + E+ P GT V    A D D    ++R
Sbjct: 1031 KNLSLSSTVFLSIDVEDQNDHSPSFQDELIVISVEENVPIGTLVYVFNAKDDDGSFLNSR 1090

Query: 399  LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD-----SGGRSDTA 453
            + Y I   N      +   +   L+TV++ LD +     +LTV+A+D     +  R  + 
Sbjct: 1091 IQYYIESHNPGTNPFLIHPSFGTLVTVSR-LDRESIPTVILTVTASDQAVNVTDRRLRSL 1149

Query: 454  MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513
              QI I D N++ P F + P  A V ED  +G+ V  ++A D D G N ++TYS+ S   
Sbjct: 1150 TAQIVILDVNDHNPTFISFP-NAHVKEDVTVGSLVHHITAHDPDEGRNGKVTYSILS--G 1206

Query: 514  NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
            NE     +  F+++  +G +TT   LD E  + ++LTV A D G P+LS +  + ++V+D
Sbjct: 1207 NE-----NMTFMLDESSGLLTTTCPLDYEMKTQHILTVLALDDGTPALSSSQTLTVTVLD 1261

Query: 574  VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633
            VND  PVFKQ LY A++ E+   G  V++V A D D G+N ++ +E+ P    E  F I+
Sbjct: 1262 VNDEAPVFKQHLYEASVKENQNPGEFVTRVEALDRDSGVNSKLQFEIMPGASFE-LFEIN 1320

Query: 634  PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693
              +G + T   LDRE      L+ +  DGG P  SST  +   +ED ND  P F      
Sbjct: 1321 SDTGEVVTTTILDREIQEVFTLRVLVRDGGFPSLSSTTTILCTVEDENDHAPEFIVSSYD 1380

Query: 694  FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753
              + EN      +  + A D D G N  V Y I  G+    F++    G    EL T   
Sbjct: 1381 IEVLENQE-PEVVYTVLASDMDAGNNRAVEYHIIDGNTDECFTINEMSG----ELSTTRA 1435

Query: 754  LDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAP 792
            LD E     + LVI  +    PP  + + +++ V D ND++P
Sbjct: 1436 LDREQ-ISNFTLVILCSDLGDPPRSSVIHLQVRVLDANDHSP 1476



 Score =  208 bits (507), Expect = 2e-51
 Identities = 172/568 (30%), Positives = 259/568 (45%), Gaps = 34/568 (5%)

Query: 324  LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF---MPG-QYEVELAEDE 379
            LDRE +  +++ V  TD G PPR+AT                F   +PG +  V++ E +
Sbjct: 797  LDREHRGHHEMTVLVTDRGSPPRNATMAVYVSVTDINDNRPFFPQCLPGKELHVKVLEGQ 856

Query: 380  PPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437
            P    V T+ A D DE N     Y ++  ++   F I + NG    T     D++    Y
Sbjct: 857  PVNMLVTTVFAKDPDEGNNAEVTYSVSSEDSSDHFKIDANNGEIRTTTILSYDYRPS--Y 914

Query: 438  VLTVSATDSG--GRSDTAMVQINITD-ANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494
             ++V ATD G       A+V I +   +   A + +N  +        P     L+ S+ 
Sbjct: 915  RMSVIATDQGVPPLQGQAVVNIQVIPLSKGRAIMSQNIRHLIIPENLKPTKIMSLIKSSD 974

Query: 495  DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554
                  N ++ +S+ ++         D  F I+  TG +  +K LD ET S YL  V   
Sbjct: 975  HLQQHYNGKLHFSIVAD-------DKDGHFEIDSSTGDLFLSKELDYETTSHYLFRVITT 1027

Query: 555  DGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG-L 612
            D     SLS T  + I V D ND+ P F+ +L   ++ E+  +GT V    A D D   L
Sbjct: 1028 DHSKNLSLSSTVFLSIDVEDQNDHSPSFQDELIVISVEENVPIGTLVYVFNAKDDDGSFL 1087

Query: 613  NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG---TPPQSS 669
            N RI Y ++  +     F+I P+ G + T   LDRES+ T  L   A D     T  +  
Sbjct: 1088 NSRIQYYIESHNPGTNPFLIHPSFGTLVTVSRLDRESIPTVILTVTASDQAVNVTDRRLR 1147

Query: 670  TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729
            ++   I I D+ND  P F S     ++ E+  +G+ +  I AHDPDEG N  V YSI  G
Sbjct: 1148 SLTAQIVILDVNDHNPTFIS-FPNAHVKEDVTVGSLVHHITAHDPDEGRNGKVTYSILSG 1206

Query: 730  DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA--ASPPLWNDVRVEILVTDV 787
            +++ +F L+   G     L T   LDYE   +    V+     +P L +   + + V DV
Sbjct: 1207 NENMTFMLDESSGL----LTTTCPLDYEMKTQHILTVLALDDGTPALSSSQTLTVTVLDV 1262

Query: 788  NDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDAD--VTDKLQYRILSGNNANLILLNE 844
            ND APV K   +   + K+    G F  RV A D D  V  KLQ+ I+ G +  L  +N 
Sbjct: 1263 NDEAPVFKQ-HLYEASVKENQNPGEFVTRVEALDRDSGVNSKLQFEIMPGASFELFEINS 1321

Query: 845  TTGSMTLSPQLNTNVPKLATMEVSVTDG 872
             TG +  +  L+  + ++ T+ V V DG
Sbjct: 1322 DTGEVVTTTILDREIQEVFTLRVLVRDG 1349



 Score =  166 bits (403), Expect = 9e-39
 Identities = 138/478 (28%), Positives = 219/478 (45%), Gaps = 35/478 (7%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTAD 68
            +I + D N+++P F ++ Y  S+ E A  G+T++T    D D   +N  VEY+I  ++ +
Sbjct: 2081 EIGIEDMNNYAPEFTVKSYNLSLSEDALVGSTLVTFSNIDHDWTRENTYVEYSI--ISGN 2138

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
            + N               + V       G L+   SLDRE  A + +++ A+D   P   
Sbjct: 2139 SQNNFHVETKFFHSEYPYKQV-------GYLVLLHSLDREASASHELVILASDSGCP--- 2188

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             LSSTA I + ++D NDN P FS  +Y   V E   +  +  I  + A D D G+++ I 
Sbjct: 2189 PLSSTAVISIQVLDVNDNPPNFSSLSYHTHVKESTPLGSH--ITVVSANDRDTGSHAEII 2246

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            Y II GN +  F ++  +G + L+K LDYE++  + L ++A D       +   + +++ 
Sbjct: 2247 YNIISGNEKGHFYLEENTGVLYLIKPLDYEKMTKFTLTVQASD-AEKKHFSFAVVFVSVL 2305

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY-----TG 303
            D ND+AP+F  S F   V EN+PI  +I  + A D D G   ELTY++    +     + 
Sbjct: 2306 DDNDHAPQFMFSSFSCIVPENLPISSTICSINALDFDAGPYGELTYSIVSPCFLTHGMSY 2365

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
            + DL   IDP +G ++    LD E   KY L V A D GD   +A+              
Sbjct: 2366 DHDL-FLIDPLTGDIHAKQILDYENGNKYCLTVQAKDKGD--ATASLVVWVDIEGIDEFE 2422

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRG 421
              F   QY   L E       +  + A+DAD   D  + Y +  G +   FS+   NG  
Sbjct: 2423 PIFTQDQYFFTLPEKNKDRQLIGRVEASDADAGIDGVILYSL--GTSSPFFSVNKTNGNI 2480

Query: 422  LITVAQPLDFKQ-------ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENA 472
             +  A PL   Q       E + +     +DS   S T  V ++ +       VF ++
Sbjct: 2481 YLIRALPLIKSQLNKEDTLEMKIIAHSPKSDSKFASCTVFVNVSFSSEGTPLAVFASS 2538



 Score =  134 bits (324), Expect = 3e-29
 Identities = 131/439 (29%), Positives = 191/439 (43%), Gaps = 28/439 (6%)

Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT--AMVQINITDANNYAPVFENAPYTA 476
           G G+I +  PL   +     L VSA D GG +    A V I+I         FE   YT 
Sbjct: 325 GEGIIYLTLPLSHLESTTLSLMVSAQDGGGLTAVINADVTIHIFQTTLAPAEFERPKYTF 384

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
            V+ED P  + +  V A +  +  +  I Y +SS            +F I+P+ G I T 
Sbjct: 385 LVYEDVPEDSPIGTVKAREP-LNSSEPIFYRISS-------GDLGGKFSIHPRLGTIRTR 436

Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
           K LD ET    +LTV A+ G  P+ S +T+V I+V+DVNDN P F +      I +    
Sbjct: 437 KPLDHETQPVVVLTVQAQLGSAPACS-STEVNITVMDVNDNHPAFLRTSDEIRISQTTPP 495

Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
           GT++    A D D G NG I Y +     + G F ID A GV+  N +L         L 
Sbjct: 496 GTALYLARAEDRDSGRNGLIRYSI--ASPQPGVFAIDRALGVLFLNGSLGAGEQRELTLT 553

Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPP-VFESDCLTFYISENSPIGTTIGEIRAHD-P 714
             A D G  PQ++ +++ + IE    SP   FE       +SE+    T + + +AH   
Sbjct: 554 LRAEDQGVHPQAALLVLTVVIEKREHSPSWTFEHLVYQVEVSESLSPMTQMLQTQAHPLG 613

Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP- 773
            +   + + YS++   DS  F +    G     +      DYES  + Y   + A  P  
Sbjct: 614 PQRAASPLRYSLEPSVDSAMFGIRPYTG----WIYLRRQFDYES-TQTYNFRVFAWIPED 668

Query: 774 --LWN-DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQ 828
             L N    V + V D NDN+P      +     +   P G  G++ A D D     +L 
Sbjct: 669 GFLQNVSTTVIVRVWDENDNSPTFLHDVLFLKVEESPVPQGVIGKITAIDMDSGKNGQLL 728

Query: 829 YRILSGNNANLILLNETTG 847
           Y +LS  +     +N  TG
Sbjct: 729 YFLLS--DGKFFKMNPNTG 745



 Score = 98.3 bits (234), Expect = 3e-18
 Identities = 111/447 (24%), Positives = 189/447 (42%), Gaps = 24/447 (5%)

Query: 73  EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132
           E A          V ++ +I G  G +     L   +    +++V A D    ++  +++
Sbjct: 304 EAASADGEAAARYVANLAKILGE-GIIYLTLPLSHLESTTLSLMVSAQDGGG-LTAVINA 361

Query: 133 TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192
             TIH  I        +F    YT  V ED+   D+P I  +KA +  + ++  I Y I 
Sbjct: 362 DVTIH--IFQTTLAPAEFERPKYTFLVYEDVP-EDSP-IGTVKAREP-LNSSEPIFYRIS 416

Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252
            G+   +FSI    G +   K LD+E      L ++AQ G +P+ S+T ++ I + DVND
Sbjct: 417 SGDLGGKFSIHPRLGTIRTRKPLDHETQPVVVLTVQAQLGSAPACSST-EVNITVMDVND 475

Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312
           N P F  +  +  +S+  P G ++   +A D D G N  + Y++      G       ID
Sbjct: 476 NHPAFLRTSDEIRISQTTPPGTALYLARAEDRDSGRNGLIRYSIASPQ-PG----VFAID 530

Query: 313 PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX-XXXFMPGQY 371
              G ++ +G L    Q +  L + A D G  P++A                  F    Y
Sbjct: 531 RALGVLFLNGSLGAGEQRELTLTLRAEDQGVHPQAALLVLTVVIEKREHSPSWTFEHLVY 590

Query: 372 EVELAEDEPPGTPVVTLTATDADED---NRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
           +VE++E   P T ++   A         + L Y +        F I      G I + + 
Sbjct: 591 QVEVSESLSPMTQMLQTQAHPLGPQRAASPLRYSLEPSVDSAMFGIRPYT--GWIYLRRQ 648

Query: 429 LDFKQERRYVLTVSA---TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
            D++  + Y   V A    D   ++ +  V + + D N+ +P F +      V E++P+ 
Sbjct: 649 FDYESTQTYNFRVFAWIPEDGFLQNVSTTVIVRVWDENDNSPTFLHDVLFLKV-EESPVP 707

Query: 486 TTVL-VVSATDSDVGINAQITYSLSSE 511
             V+  ++A D D G N Q+ Y L S+
Sbjct: 708 QGVIGKITAIDMDSGKNGQLLYFLLSD 734



 Score = 90.2 bits (214), Expect = 7e-16
 Identities = 62/236 (26%), Positives = 101/236 (42%), Gaps = 11/236 (4%)

Query: 644  ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT-----FYISE 698
            ALDRE    H++  +  D G+PP+++T+ V++ + DIND+ P F   CL        + E
Sbjct: 796  ALDREHRGHHEMTVLVTDRGSPPRNATMAVYVSVTDINDNRPFF-PQCLPGKELHVKVLE 854

Query: 699  NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758
              P+   +  + A DPDEG NA V YS+   D S+ F ++   G  +    T++  DY  
Sbjct: 855  GQPVNMLVTTVFAKDPDEGNNAEVTYSVSSEDSSDHFKIDANNG--EIRTTTILSYDYRP 912

Query: 759  PRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKD---FQIIFNNYKDCFPVGPFGR 815
              +   +      PPL     V I V  ++    +M       II  N K    +     
Sbjct: 913  SYRMSVIATDQGVPPLQGQAVVNIQVIPLSKGRAIMSQNIRHLIIPENLKPTKIMSLIKS 972

Query: 816  VPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
                      KL + I++ +      ++ +TG + LS +L+          V  TD
Sbjct: 973  SDHLQQHYNGKLHFSIVADDKDGHFEIDSSTGDLFLSKELDYETTSHYLFRVITTD 1028



 Score = 80.2 bits (189), Expect = 8e-13
 Identities = 82/305 (26%), Positives = 131/305 (42%), Gaps = 44/305 (14%)

Query: 2   SVPFCIHQQIN--VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVE 59
           S P C   ++N  V+D ND+ P F     E  + +    GT +   +A D+D G+N  + 
Sbjct: 457 SAPACSSTEVNITVMDVNDNHPAFLRTSDEIRISQTTPPGTALYLARAEDRDSGRNGLIR 516

Query: 60  YTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKA 119
           Y+I        +P+               VF ID   G L    SL   +    T+ ++A
Sbjct: 517 YSI-------ASPQPG-------------VFAIDRALGVLFLNGSLGAGEQRELTLTLRA 556

Query: 120 TDQ-ASPVSDRLSSTATIHVNIIDDNDNYPQ--FSEKTYTVSVDEDISVTDNPVIAKIKA 176
            DQ   P +  L  T      +I+  ++ P   F    Y V V E +S    P+   ++ 
Sbjct: 557 EDQGVHPQAALLVLTV-----VIEKREHSPSWTFEHLVYQVEVSESLS----PMTQMLQT 607

Query: 177 TDADVG---ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA---Q 230
               +G   A S +RY++        F I   +G + L +  DYE  ++Y   + A   +
Sbjct: 608 QAHPLGPQRAASPLRYSLEPSVDSAMFGIRPYTGWIYLRRQFDYESTQTYNFRVFAWIPE 667

Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRF-YTSLFQESVSENVPIGYSIVRVQAYDADEGVN 289
           DG   + S T  +++ + D NDN+P F +  LF +     VP G  I ++ A D D G N
Sbjct: 668 DGFLQNVSTT--VIVRVWDENDNSPTFLHDVLFLKVEESPVPQGV-IGKITAIDMDSGKN 724

Query: 290 AELTY 294
            +L Y
Sbjct: 725 GQLLY 729



 Score = 74.5 bits (175), Expect = 4e-11
 Identities = 57/160 (35%), Positives = 78/160 (48%), Gaps = 17/160 (10%)

Query: 491 VSATDSDVGINAQITYSL-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET-MSGYL 548
           V+A+D+D G+   I YSL    +S EA     Q F I+P  G I  ++ +DRE   + Y 
Sbjct: 79  VTASDADSGLYGFIEYSLYDGFLSYEA----PQAFRIDPHDGQICVSQDIDRERDPATYD 134

Query: 549 LTVTARDGGVP----------SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
           L V A+DG              LS    V + + DVNDN PVF    Y  +I ++   GT
Sbjct: 135 LLVEAKDGDEQRMTHLALVKGGLSAQAFVRVDLEDVNDNHPVFNPSTYVTSISDETQPGT 194

Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638
            +  V ATD D G+ G + YEL P       F ID  +G+
Sbjct: 195 EIINVLATDQDSGIYGTVAYELIP-GNVSSLFTIDSTTGL 233



 Score = 69.3 bits (162), Expect = 1e-09
 Identities = 56/169 (33%), Positives = 84/169 (49%), Gaps = 16/169 (9%)

Query: 601 SQVGATDADVGLNGRIHYEL-DPKDREEG--SFVIDPASGVIRTNKALDRE-SVATHDLK 656
           ++V A+DAD GL G I Y L D     E   +F IDP  G I  ++ +DRE   AT+DL 
Sbjct: 77  TEVTASDADSGLYGFIEYSLYDGFLSYEAPQAFRIDPHDGQICVSQDIDRERDPATYDLL 136

Query: 657 AVAIDGGTPPQ----------SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706
             A DG               S+   V + +ED+ND+ PVF        IS+ +  GT I
Sbjct: 137 VEAKDGDEQRMTHLALVKGGLSAQAFVRVDLEDVNDNHPVFNPSTYVTSISDETQPGTEI 196

Query: 707 GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG--SDKAELVTMVD 753
             + A D D G    V Y +  G+ S+ F++++  G  S + E+++ V+
Sbjct: 197 INVLATDQDSGIYGTVAYELIPGNVSSLFTIDSTTGLYSPEVEILSAVN 245



 Score = 69.3 bits (162), Expect = 1e-09
 Identities = 43/126 (34%), Positives = 63/126 (50%), Gaps = 10/126 (7%)

Query: 90  FRIDGRSGALLTRASLDREK-VARYTVLVKATD-------QASPVSDRLSSTATIHVNII 141
           FRID   G +     +DRE+  A Y +LV+A D         + V   LS+ A + V++ 
Sbjct: 109 FRIDPHDGQICVSQDIDRERDPATYDLLVEAKDGDEQRMTHLALVKGGLSAQAFVRVDLE 168

Query: 142 DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFS 201
           D NDN+P F+  TY  S+ ++        I  + ATD D G    + Y +I GN    F+
Sbjct: 169 DVNDNHPVFNPSTYVTSISDE--TQPGTEIINVLATDQDSGIYGTVAYELIPGNVSSLFT 226

Query: 202 IDSLSG 207
           IDS +G
Sbjct: 227 IDSTTG 232



 Score = 60.1 bits (139), Expect = 9e-07
 Identities = 45/154 (29%), Positives = 63/154 (40%), Gaps = 13/154 (8%)

Query: 279 VQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ-AKYQLLVT 337
           V A DAD G+   + Y++ D   +        IDP  G +  S  +DRE   A Y LLV 
Sbjct: 79  VTASDADSGLYGFIEYSLYDGFLSYEAPQAFRIDPHDGQICVSQDIDRERDPATYDLLVE 138

Query: 338 ATDGGDPPR----------SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387
           A DG +             SA A               F P  Y   ++++  PGT ++ 
Sbjct: 139 AKDGDEQRMTHLALVKGGLSAQAFVRVDLEDVNDNHPVFNPSTYVTSISDETQPGTEIIN 198

Query: 388 LTATDADED--NRLHYEITGGNTRGRFSITSQNG 419
           + ATD D      + YE+  GN    F+I S  G
Sbjct: 199 VLATDQDSGIYGTVAYELIPGNVSSLFTIDSTTG 232



 Score = 59.7 bits (138), Expect = 1e-06
 Identities = 44/159 (27%), Positives = 72/159 (45%), Gaps = 19/159 (11%)

Query: 173 KIKATDADVGANSAIRYAIIGG----NTQMQFSIDSLSGDVSLVKTLDYEQ-VRSYRLVI 227
           ++ A+DAD G    I Y++  G         F ID   G + + + +D E+   +Y L++
Sbjct: 78  EVTASDADSGLYGFIEYSLYDGFLSYEAPQAFRIDPHDGQICVSQDIDRERDPATYDLLV 137

Query: 228 RAQDGGSPSRSNTTQLL----------INIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277
            A+DG     ++   +           +++ DVNDN P F  S +  S+S+    G  I+
Sbjct: 138 EAKDGDEQRMTHLALVKGGLSAQAFVRVDLEDVNDNHPVFNPSTYVTSISDETQPGTEII 197

Query: 278 RVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316
            V A D D G+   + Y +      GNV    TID  +G
Sbjct: 198 NVLATDQDSGIYGTVAYEL----IPGNVSSLFTIDSTTG 232



 Score = 51.2 bits (117), Expect = 4e-04
 Identities = 25/70 (35%), Positives = 38/70 (54%)

Query: 439 LTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498
           +T  A   GG S  A V++++ D N+  PVF  + Y  S+ ++   GT ++ V ATD D 
Sbjct: 147 MTHLALVKGGLSAQAFVRVDLEDVNDNHPVFNPSTYVTSISDETQPGTEIINVLATDQDS 206

Query: 499 GINAQITYSL 508
           GI   + Y L
Sbjct: 207 GIYGTVAYEL 216



 Score = 41.5 bits (93), Expect = 0.32
 Identities = 18/53 (33%), Positives = 29/53 (54%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
           ++++ D ND+ PVF    Y  S+ +    GT ++ + ATDQD G    V Y +
Sbjct: 164 RVDLEDVNDNHPVFNPSTYVTSISDETQPGTEIINVLATDQDSGIYGTVAYEL 216


>UniRef50_UPI0000F3174E Cluster: dachsous 2 isoform 1; n=9;
            Theria|Rep: dachsous 2 isoform 1 - Bos Taurus
          Length = 2131

 Score =  351 bits (864), Expect = 1e-94
 Identities = 266/871 (30%), Positives = 415/871 (47%), Gaps = 57/871 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIG-KNAEVEYTIELVTADT 69
            + V D NDHSP F  +    SV E    GT V    A D D    N+ ++Y IE      
Sbjct: 257  VAVEDQNDHSPSFREEFIVISVPENTPVGTLVHIFNAKDGDGSFLNSRIQYFIE-ANHPG 315

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            +NP                 F I   SG L+T + LDRE+V    + V A+DQA  V+DR
Sbjct: 316  MNP-----------------FLIHPSSGTLVTTSPLDRERVPTVVLTVTASDQAVNVTDR 358

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
               +    V I+D ND+ P F+       V ED +V    ++  I A D D G N  + +
Sbjct: 359  RLRSLMAKVVILDVNDHSPTFTSFPIA-HVREDAAV--GSLVHHITAQDPDAGRNGRVTF 415

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            +I+ GN  M F +D  SG ++    LDYE    + L + A DGG+P+ S++  L I + D
Sbjct: 416  SILSGNENMAFMLDESSGFLTTASPLDYEIKSQHILTLLALDGGTPTLSSSQTLTITVLD 475

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            VND AP F   L++ SV EN   G  + RV+A D D G+N++L + +      G   +  
Sbjct: 476  VNDEAPVFKQHLYEASVKENQNPGEFVTRVEAVDRDSGINSKLQFEI----MPGASFMLF 531

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             I+  +G V T+  LDRE Q    L V   DGG P  S T                 +  
Sbjct: 532  QINSDTGEVVTAATLDREVQEVLTLRVLVHDGGAPALSGTTVILCTVRDENDHAPQIVVP 591

Query: 370  QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
            + ++E+ E++ PG  V T  A+D D   +  + Y I  GNT   F++   +G   ++  +
Sbjct: 592  RDDIEVLENQEPGL-VYTFLASDMDAGSNGAVTYHIIDGNTDEYFAVNEMSGE--LSTTR 648

Query: 428  PLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
             LD ++   + L +  +D G   +S TA +Q+ + D N+++P F    Y ASV EDA +G
Sbjct: 649  ALDREEVSNFTLVILCSDLGSPPQSSTAQLQVRVLDDNDHSPSFPRLQYQASVREDAQVG 708

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
            TTVLV+S+ D D G+N Q  YSL  E S          F I+P  G + T++ LDRE  S
Sbjct: 709  TTVLVLSSADEDEGLNGQTMYSLVHESSG--------AFTIDPVAGTLRTSRALDREARS 760

Query: 546  GYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
             ++L   ARD GV  S S T  +++ V DVNDN PV +Q      +   +    + + + 
Sbjct: 761  EHVLKAVARDCGVQGSRSTTVVIKVHVTDVNDNSPVLEQNPLDIFLSSQSPTNQTAAILR 820

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            A+D D G NG + +        +    I+  +G I+  +    E      L+  A+D G 
Sbjct: 821  ASDPDSGPNGTVTFSF---AEPQSVLSINEYTGAIQLQQIPSSEYFPIW-LQLKAVDQGV 876

Query: 665  PPQSST--VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
            P +++T  +++H++ ED+  S   F        + EN   GT+I  I+A  PD   ++ +
Sbjct: 877  PARTTTGLLVIHMEGEDVRIS---FSQHLYKGIVPENCEAGTSIVTIKAFAPDSIRDS-I 932

Query: 723  HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEI 782
             YS+  G++   FSL ++ G    +    +D +    RK+ +L++ A S       +V +
Sbjct: 933  KYSVFSGNEDGVFSLCSKSGEVTVKEPKFLDFEV---RKEVQLIVLAESRGRKAYSKVAV 989

Query: 783  LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNNANLI 840
             + D+ND+ P  +      +  +  F      +V A D D      ++Y ILSGN  N+ 
Sbjct: 990  FIQDLNDHPPHFEQSVYQVSVSEGQFYNHHIVQVFATDLDSGSNGLVEYSILSGNQGNVF 1049

Query: 841  LLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
             ++  +G +T S  L+       ++ V   D
Sbjct: 1050 QMDPLSGVLTASAILDYEYTSTYSLIVQAMD 1080



 Score =  314 bits (770), Expect = 3e-83
 Identities = 256/875 (29%), Positives = 412/875 (47%), Gaps = 75/875 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I VLD ND +PVF+   YEASV+E  + G  V  ++A D+D G N+++++ I +  A  +
Sbjct: 471  ITVLDVNDEAPVFKQHLYEASVKENQNPGEFVTRVEAVDRDSGINSKLQFEI-MPGASFM 529

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                              +F+I+  +G ++T A+LDRE     T+ V   D  +P    L
Sbjct: 530  ------------------LFQINSDTGEVVTAATLDREVQEVLTLRVLVHDGGAPA---L 568

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP---VIAKIKATDADVGANSAI 187
            S T  I   + D+ND+ PQ       V   +DI V +N    ++    A+D D G+N A+
Sbjct: 569  SGTTVILCTVRDENDHAPQI------VVPRDDIEVLENQEPGLVYTFLASDMDAGSNGAV 622

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
             Y II GNT   F+++ +SG++S  + LD E+V ++ LVI   D GSP +S+T QL + +
Sbjct: 623  TYHIIDGNTDEYFAVNEMSGELSTTRALDREEVSNFTLVILCSDLGSPPQSSTAQLQVRV 682

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
             D ND++P F    +Q SV E+  +G +++ + + D DEG+N +  Y++  +  +G    
Sbjct: 683  LDDNDHSPSFPRLQYQASVREDAQVGTTVLVLSSADEDEGLNGQTMYSLVHES-SG---- 737

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATD-GGDPPRSATATXXXXXXXXXXXXXXF 366
              TIDP +G + TS  LDRE ++++ L   A D G    RS T                 
Sbjct: 738  AFTIDPVAGTLRTSRALDREARSEHVLKAVARDCGVQGSRSTTVVIKVHVTDVNDNSPVL 797

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
                 ++ L+   P       L A+D D         +    +   SI    G       
Sbjct: 798  EQNPLDIFLSSQSPTNQTAAILRASDPDSGPNGTVTFSFAEPQSVLSINEYTG---AIQL 854

Query: 427  QPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
            Q +   +     L + A D G   R+ T ++ I++ +  +    F    Y   V E+   
Sbjct: 855  QQIPSSEYFPIWLQLKAVDQGVPARTTTGLLVIHM-EGEDVRISFSQHLYKGIVPENCEA 913

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN--KLLDRE 542
            GT+++ + A   D  I   I YS+ S   NE     D  F +  ++G +T    K LD E
Sbjct: 914  GTSIVTIKAFAPD-SIRDSIKYSVFS--GNE-----DGVFSLCSKSGEVTVKEPKFLDFE 965

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
                  L V A   G  + S    V + + D+ND+ P F+Q +Y  ++ E       + Q
Sbjct: 966  VRKEVQLIVLAESRGRKAYS---KVAVFIQDLNDHPPHFEQSVYQVSVSEGQFYNHHIVQ 1022

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
            V ATD D G NG + Y +     +   F +DP SGV+  +  LD E  +T+ L   A+D 
Sbjct: 1023 VFATDLDSGSNGLVEYSI-LSGNQGNVFQMDPLSGVLTASAILDYEYTSTYSLIVQAMDK 1081

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVF-ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
            G P  S T ++ I++ DIND+ P+F  S+ +   I ENS  GT +  I  +D D  P A 
Sbjct: 1082 GMPRLSDTTVIKIQVTDINDNAPIFLPSEAVE--IVENSLPGTIVTRISVYDVDSNP-AF 1138

Query: 722  VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781
                +K  +    F+++   G     +V +  LD+E    KYEL I+ +      +  V 
Sbjct: 1139 TFSFVKESNSGTKFAIDRNTG----VVVLVETLDFEE-ATKYELQIQISDLVHQTEGTVT 1193

Query: 782  ILVTDVNDNAPVMK--DFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNAN 838
            + V DVNDN PV     +Q+  +   +  P+G P   + A D + ++ + YRILS  ++ 
Sbjct: 1194 VHVLDVNDNPPVFSQDSYQVTIS---ELVPLGHPVLTIVATDVESSENITYRILS--SSK 1248

Query: 839  LILLNETTGSM-TLSPQLNTNVPKLATMEVSVTDG 872
            +  ++ T G++ T++P             V  +DG
Sbjct: 1249 MFSVDPTNGTIFTINPVFLMERKSTIRFLVEASDG 1283



 Score =  312 bits (765), Expect = 1e-82
 Identities = 253/886 (28%), Positives = 404/886 (45%), Gaps = 66/886 (7%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ +LD NDHSP F      A VRE A+ G+ V  + A D D G+N  V ++I       
Sbjct: 366  KVVILDVNDHSPTFTSFPI-AHVREDAAVGSLVHHITAQDPDAGRNGRVTFSI------- 417

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            L+  +               F +D  SG L T + LD E  +++ + + A D  +P    
Sbjct: 418  LSGNE------------NMAFMLDESSGFLTTASPLDYEIKSQHILTLLALDGGTPT--- 462

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            LSS+ T+ + ++D ND  P F +  Y  SV E  +      + +++A D D G NS +++
Sbjct: 463  LSSSQTLTITVLDVNDEAPVFKQHLYEASVKE--NQNPGEFVTRVEAVDRDSGINSKLQF 520

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             I+ G + M F I+S +G+V    TLD E      L +   DGG+P+ S TT +L  +RD
Sbjct: 521  EIMPGASFMLFQINSDTGEVVTAATLDREVQEVLTLRVLVHDGGAPALSGTTVILCTVRD 580

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
             ND+AP+         V EN   G  +    A D D G N  +TY + D    GN D   
Sbjct: 581  ENDHAPQIVVPRDDIEVLENQEPGL-VYTFLASDMDAGSNGAVTYHIID----GNTDEYF 635

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             ++  SG + T+  LDRE  + + L++  +D G PP+S+TA               F   
Sbjct: 636  AVNEMSGELSTTRALDREEVSNFTLVILCSDLGSPPQSSTAQLQVRVLDDNDHSPSFPRL 695

Query: 370  QYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
            QY+  + ED   GT V+ L++ D DE  + +  Y +    + G F+I      G +  ++
Sbjct: 696  QYQASVREDAQVGTTVLVLSSADEDEGLNGQTMYSLV-HESSGAFTIDPV--AGTLRTSR 752

Query: 428  PLDFKQERRYVLTVSATD---SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
             LD +    +VL   A D    G RS T ++++++TD N+ +PV E  P    +   +P 
Sbjct: 753  ALDREARSEHVLKAVARDCGVQGSRSTTVVIKVHVTDVNDNSPVLEQNPLDIFLSSQSPT 812

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
              T  ++ A+D D G N  +T+S          A       IN  TGAI   ++   E  
Sbjct: 813  NQTAAILRASDPDSGPNGTVTFSF---------AEPQSVLSINEYTGAIQLQQIPSSEYF 863

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
              + L + A D GVP+ + TT + +  ++  D    F Q LY   + E+   GTS+  + 
Sbjct: 864  PIW-LQLKAVDQGVPART-TTGLLVIHMEGEDVRISFSQHLYKGIVPENCEAGTSIVTIK 921

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASG--VIRTNKALDRESVATHDLKAVAIDG 662
            A   D  +   I Y +     E+G F +   SG   ++  K LD E      L  +A   
Sbjct: 922  AFAPD-SIRDSIKYSVF-SGNEDGVFSLCSKSGEVTVKEPKFLDFEVRKEVQLIVLAESR 979

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
            G    S    V + I+D+ND PP FE       +SE       I ++ A D D G N +V
Sbjct: 980  GRKAYSK---VAVFIQDLNDHPPHFEQSVYQVSVSEGQFYNHHIVQVFATDLDSGSNGLV 1036

Query: 723  HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVR 779
             YSI  G+  N F ++   G   A  +    LDYE     Y L+++A     P L +   
Sbjct: 1037 EYSILSGNQGNVFQMDPLSGVLTASAI----LDYEY-TSTYSLIVQAMDKGMPRLSDTTV 1091

Query: 780  VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYR-ILSGNNAN 838
            ++I VTD+NDNAP+    + +    ++  P     R+  YD D      +  +   N+  
Sbjct: 1092 IKIQVTDINDNAPIFLPSEAV-EIVENSLPGTIVTRISVYDVDSNPAFTFSFVKESNSGT 1150

Query: 839  LILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884
               ++  TG + L   L+        +++ ++D V++ +  + + V
Sbjct: 1151 KFAIDRNTGVVVLVETLDFEEATKYELQIQISDLVHQTEGTVTVHV 1196



 Score =  283 bits (694), Expect = 5e-74
 Identities = 262/866 (30%), Positives = 396/866 (45%), Gaps = 75/866 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            Q+ VLD NDHSP F   QY+ASVRE A  GTTVL L + D+D G N +  Y++   ++  
Sbjct: 679  QVRVLDDNDHSPSFPRLQYQASVREDAQVGTTVLVLSSADEDEGLNGQTMYSLVHESSGA 738

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                                F ID  +G L T  +LDRE  AR   ++KA  +   V   
Sbjct: 739  --------------------FTIDPVAGTLRTSRALDRE--ARSEHVLKAVARDCGVQGS 776

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             S+T  I V++ D NDN P   +    + +    S T N   A ++A+D D G N  + +
Sbjct: 777  RSTTVVIKVHVTDVNDNSPVLEQNPLDIFLSSQ-SPT-NQTAAILRASDPDSGPNGTVTF 834

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            +      Q   SI+  +G + L +    E    + L ++A D G P+R+ T  L+I++  
Sbjct: 835  SF--AEPQSVLSINEYTGAIQLQQIPSSEYFPIW-LQLKAVDQGVPARTTTGLLVIHMEG 891

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
              D    F   L++  V EN   G SIV ++A+ A + +   + Y++    ++GN D   
Sbjct: 892  -EDVRISFSQHLYKGIVPENCEAGTSIVTIKAF-APDSIRDSIKYSV----FSGNEDGVF 945

Query: 310  TIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
            ++  +SG V       LD E + + QL+V A   G   R A +               F 
Sbjct: 946  SLCSKSGEVTVKEPKFLDFEVRKEVQLIVLAESRG---RKAYSKVAVFIQDLNDHPPHFE 1002

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITV 425
               Y+V ++E +     +V + ATD D  +   + Y I  GN    F +   +G  ++T 
Sbjct: 1003 QSVYQVSVSEGQFYNHHIVQVFATDLDSGSNGLVEYSILSGNQGNVFQMDPLSG--VLTA 1060

Query: 426  AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
            +  LD++    Y L V A D G    SDT +++I +TD N+ AP+F  +     + E++ 
Sbjct: 1061 SAILDYEYTSTYSLIVQAMDKGMPRLSDTTVIKIQVTDINDNAPIFLPSE-AVEIVENSL 1119

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
             GT V  +S  D D   N   T+S   E SN        +F I+  TG +   + LD E 
Sbjct: 1120 PGTIVTRISVYDVDS--NPAFTFSFVKE-SNSGT-----KFAIDRNTGVVVLVETLDFEE 1171

Query: 544  MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
             + Y L +   D  +   ++ T V + V+DVNDN PVF Q  Y   I E   +G  V  +
Sbjct: 1172 ATKYELQIQISD--LVHQTEGT-VTVHVLDVNDNPPVFSQDSYQVTISELVPLGHPVLTI 1228

Query: 604  GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT-NKALDRESVATHDLKAVAIDG 662
             ATD +   N  I Y +    +    F +DP +G I T N     E  +T      A DG
Sbjct: 1229 VATDVESSEN--ITYRILSSSK---MFSVDPTNGTIFTINPVFLMERKSTIRFLVEASDG 1283

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAV 721
            G P   +  +V  +I+D+N+  P F  +     +SE++P+G T+      D D    N  
Sbjct: 1284 GFPDLKAVTLVETEIQDMNNYAPEFAIEYYNLSLSEDTPVGRTLVTFSTIDHDWTRENTH 1343

Query: 722  VHYSIKGGDDSNSFSLETR----QGSDK--AELVTMVDLDYESPRKKYELVIRA---ASP 772
            V YSI  G+  N+F +ET     + S K    LV +  LD E+    +ELV+ A     P
Sbjct: 1344 VEYSIISGNSQNNFHVETSFIHSEYSYKQVGYLVLLHHLDREATAS-HELVLLAFDHGCP 1402

Query: 773  PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYR 830
            PL +   V I V DV+DN P     +   +  +   P  P   V A D DV    ++ Y 
Sbjct: 1403 PLSSSATVSIEVLDVDDNPPAFSSLEYYVHIKESTPPGSPIIVVSASDRDVGSHAEVSYY 1462

Query: 831  ILSGNNANLILLNETTGSMTLSPQLN 856
            + SGN      L E TG ++L   L+
Sbjct: 1463 LTSGNEKQHFCLEEKTGVLSLIKPLD 1488



 Score =  279 bits (685), Expect = 6e-73
 Identities = 238/802 (29%), Positives = 368/802 (45%), Gaps = 61/802 (7%)

Query: 11  INVLDCNDHSPVFEM----QQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           ++V D ND+ P F      ++    V EG      V T+ A D D G NAEV Y++    
Sbjct: 41  VSVTDINDNRPYFPQCLAGKELYVKVLEGQPVNMLVTTVFAKDLDEGNNAEVIYSV---- 96

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
               + ED+            D F+ID  SG + T   L R+    Y + V A+DQ  P 
Sbjct: 97  ----SSEDSS-----------DHFKIDANSGEIRTTRVLSRDYGPSYRMTVIASDQGVP- 140

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD-ADVGANS 185
              L   A I++ +I  +      S+    + + E++  T   V++ IK+ D        
Sbjct: 141 --PLQGQAVINIQVIPLSKGRTVISQNIRHLVIPENLKPT--KVMSLIKSPDHLQRQHGG 196

Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRL-VIRAQDGGSPSRSNTTQLL 244
            + ++I   +    F +DS +GD+ L K LDYE +  Y L V+      +P  ++T  L 
Sbjct: 197 KLHFSIAADDKDGHFEVDSSTGDLFLSKELDYEMMSHYLLRVVTKDHSRNPPVNSTVFLS 256

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG-VNAELTYTMTDKDYTG 303
           + + D ND++P F       SV EN P+G  +    A D D   +N+ + Y   + ++ G
Sbjct: 257 VAVEDQNDHSPSFREEFIVISVPENTPVGTLVHIFNAKDGDGSFLNSRIQY-FIEANHPG 315

Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG--GDPPRSATATXXXXXXXXXX 361
               P  I P SG + T+  LDRE      L VTA+D       R   +           
Sbjct: 316 M--NPFLIHPSSGTLVTTSPLDRERVPTVVLTVTASDQAVNVTDRRLRSLMAKVVILDVN 373

Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419
                        + ED   G+ V  +TA D D   + R+ + I  GN    F +   + 
Sbjct: 374 DHSPTFTSFPIAHVREDAAVGSLVHHITAQDPDAGRNGRVTFSILSGNENMAFMLDESS- 432

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477
            G +T A PLD++ + +++LT+ A D G    S +  + I + D N+ APVF+   Y AS
Sbjct: 433 -GFLTTASPLDYEIKSQHILTLLALDGGTPTLSSSQTLTITVLDVNDEAPVFKQHLYEAS 491

Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
           V E+   G  V  V A D D GIN+++ + +    S          F IN  TG + T  
Sbjct: 492 VKENQNPGEFVTRVEAVDRDSGINSKLQFEIMPGAS-------FMLFQINSDTGEVVTAA 544

Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
            LDRE      L V   DGG P+LS TT +  +V D ND+ P          ++E+   G
Sbjct: 545 TLDREVQEVLTLRVLVHDGGAPALSGTTVILCTVRDENDHAPQIVVPRDDIEVLENQEPG 604

Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
             V    A+D D G NG + Y +   + +E  F ++  SG + T +ALDRE V+   L  
Sbjct: 605 L-VYTFLASDMDAGSNGAVTYHIIDGNTDE-YFAVNEMSGELSTTRALDREEVSNFTLVI 662

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
           +  D G+PPQSST  + +++ D ND  P F        + E++ +GTT+  + + D DEG
Sbjct: 663 LCSDLGSPPQSSTAQLQVRVLDDNDHSPSFPRLQYQASVREDAQVGTTVLVLSSADEDEG 722

Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND 777
            N    YS+   + S +F+++   G+    L T   LD E+ R ++ L   A    +   
Sbjct: 723 LNGQTMYSLV-HESSGAFTIDPVAGT----LRTSRALDREA-RSEHVLKAVARDCGVQGS 776

Query: 778 ----VRVEILVTDVNDNAPVMK 795
               V +++ VTDVNDN+PV++
Sbjct: 777 RSTTVVIKVHVTDVNDNSPVLE 798



 Score =  279 bits (685), Expect = 6e-73
 Identities = 244/839 (29%), Positives = 382/839 (45%), Gaps = 74/839 (8%)

Query: 13   VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72
            V D NDH+P   + + +  V E    G  V T  A+D D G N  V Y I  +  +T   
Sbjct: 578  VRDENDHAPQIVVPRDDIEVLENQEPGL-VYTFLASDMDAGSNGAVTYHI--IDGNT--- 631

Query: 73   EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132
                           + F ++  SG L T  +LDRE+V+ +T+++  +D  SP     SS
Sbjct: 632  --------------DEYFAVNEMSGELSTTRALDREEVSNFTLVILCSDLGSPPQ---SS 674

Query: 133  TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192
            TA + V ++DDND+ P F    Y  SV ED  V     +  + + D D G N    Y+++
Sbjct: 675  TAQLQVRVLDDNDHSPSFPRLQYQASVREDAQV--GTTVLVLSSADEDEGLNGQTMYSLV 732

Query: 193  GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD-GGSPSRSNTTQLLINIRDVN 251
               +   F+ID ++G +   + LD E    + L   A+D G   SRS T  + +++ DVN
Sbjct: 733  -HESSGAFTIDPVAGTLRTSRALDREARSEHVLKAVARDCGVQGSRSTTVVIKVHVTDVN 791

Query: 252  DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311
            DN+P    +     +S   P   +   ++A D D G N  +T++  +          ++I
Sbjct: 792  DNSPVLEQNPLDIFLSSQSPTNQTAAILRASDPDSGPNGTVTFSFAEPQSV------LSI 845

Query: 312  DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371
            +  +G +    Q+         L + A D G P R+ T                F    Y
Sbjct: 846  NEYTGAIQLQ-QIPSSEYFPIWLQLKAVDQGVPARTTTG-LLVIHMEGEDVRISFSQHLY 903

Query: 372  EVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQP-- 428
            +  + E+   GT +VT+ A   D   + + Y +  GN  G FS+ S++G   +TV +P  
Sbjct: 904  KGIVPENCEAGTSIVTIKAFAPDSIRDSIKYSVFSGNEDGVFSLCSKSGE--VTVKEPKF 961

Query: 429  LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
            LDF+  +   L V A +S GR   + V + I D N++ P FE + Y  SV E       +
Sbjct: 962  LDFEVRKEVQLIVLA-ESRGRKAYSKVAVFIQDLNDHPPHFEQSVYQVSVSEGQFYNHHI 1020

Query: 489  LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
            + V ATD D G N  + YS+ S        +    F ++P +G +T + +LD E  S Y 
Sbjct: 1021 VQVFATDLDSGSNGLVEYSILS-------GNQGNVFQMDPLSGVLTASAILDYEYTSTYS 1073

Query: 549  LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
            L V A D G+P LSDTT ++I V D+NDN P+F        I+E++L GT V+++   D 
Sbjct: 1074 LIVQAMDKGMPRLSDTTVIKIQVTDINDNAPIFLPS-EAVEIVENSLPGTIVTRISVYDV 1132

Query: 609  DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
            D   N    +    +      F ID  +GV+   + LD E    ++L+ + I        
Sbjct: 1133 D--SNPAFTFSFVKESNSGTKFAIDRNTGVVVLVETLDFEEATKYELQ-IQISDLVHQTE 1189

Query: 669  STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
             TV VH+   D+ND+PPVF  D     ISE  P+G  +  I A D +   N  + Y I  
Sbjct: 1190 GTVTVHVL--DVNDNPPVFSQDSYQVTISELVPLGHPVLTIVATDVESSEN--ITYRIL- 1244

Query: 729  GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVT 785
               S  FS++   G+    + T+  +     +     ++ A+    P L     VE  + 
Sbjct: 1245 -SSSKMFSVDPTNGT----IFTINPVFLMERKSTIRFLVEASDGGFPDLKAVTLVETEIQ 1299

Query: 786  DVNDNAPVMKDFQIIFNN--YKDCFPVG-PFGRVPAYDADVTDK---LQYRILSGNNAN 838
            D+N+ AP   +F I + N    +  PVG         D D T +   ++Y I+SGN+ N
Sbjct: 1300 DMNNYAP---EFAIEYYNLSLSEDTPVGRTLVTFSTIDHDWTRENTHVEYSIISGNSQN 1355



 Score =  277 bits (679), Expect = 3e-72
 Identities = 220/753 (29%), Positives = 351/753 (46%), Gaps = 72/753 (9%)

Query: 13   VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72
            + D NDH P FE   Y+ SV EG      ++ + ATD D G N  VEY+I       L+ 
Sbjct: 991  IQDLNDHPPHFEQSVYQVSVSEGQFYNHHIVQVFATDLDSGSNGLVEYSI-------LSG 1043

Query: 73   EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132
                           +VF++D  SG L   A LD E  + Y+++V+A D+  P   RLS 
Sbjct: 1044 NQG------------NVFQMDPLSGVLTASAILDYEYTSTYSLIVQAMDKGMP---RLSD 1088

Query: 133  TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192
            T  I + + D NDN P F        V+  +  T   ++ +I   D D  +N A  ++ +
Sbjct: 1089 TTVIKIQVTDINDNAPIFLPSEAVEIVENSLPGT---IVTRISVYDVD--SNPAFTFSFV 1143

Query: 193  G-GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251
               N+  +F+ID  +G V LV+TLD+E+   Y L I+  D    +    T   +++ DVN
Sbjct: 1144 KESNSGTKFAIDRNTGVVVLVETLDFEEATKYELQIQISDLVHQTEGTVT---VHVLDVN 1200

Query: 252  DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311
            DN P F    +Q ++SE VP+G+ ++ + A D +   N  +TY +             ++
Sbjct: 1201 DNPPVFSQDSYQVTISELVPLGHPVLTIVATDVESSEN--ITYRILSSSKM------FSV 1252

Query: 312  DPRSGWVYTSGQLD-RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            DP +G ++T   +   E ++  + LV A+DGG P   A                 F    
Sbjct: 1253 DPTNGTIFTINPVFLMERKSTIRFLVEASDGGFPDLKAVTLVETEIQDMNNYAPEFAIEY 1312

Query: 371  YEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSIT--------SQNG 419
            Y + L+ED P G  +VT +  D D   E+  + Y I  GN++  F +         S   
Sbjct: 1313 YNLSLSEDTPVGRTLVTFSTIDHDWTRENTHVEYSIISGNSQNNFHVETSFIHSEYSYKQ 1372

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477
             G + +   LD +    + L + A D G    S +A V I + D ++  P F +  Y   
Sbjct: 1373 VGYLVLLHHLDREATASHELVLLAFDHGCPPLSSSATVSIEVLDVDDNPPAFSSLEYYVH 1432

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            + E  P G+ ++VVSA+D DVG +A+++Y L+S   NE      Q F +  +TG ++  K
Sbjct: 1433 IKESTPPGSPIIVVSASDRDVGSHAEVSYYLTS--GNEK-----QHFCLEEKTGVLSLIK 1485

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
             LD E    ++LTV A D      S    V ++V+D ND+ P F        + E+  V 
Sbjct: 1486 PLDYEETIKFILTVQASDEERKHFSFAI-VFVNVLDDNDHAPQFMFPNLNCAVPENLPVF 1544

Query: 598  TSVSQVGATDADVGLNGRIHYELD-----PKD--REEGSFVIDPASGVIRTNKALDRESV 650
            +++  V A D D G  G + Y +      P +   +   F+IDP +G I   + LD E+ 
Sbjct: 1545 STICSVNALDFDAGPYGDMTYSIVSPCPLPHEMPHDHNFFLIDPLTGDISAQQVLDYEND 1604

Query: 651  ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710
              + L   A D      +++V+V + +E I++  P+F  D   F + E S +   IG + 
Sbjct: 1605 NKYCLIVQAKDKAD--STASVVVWVDVEGIDEFEPIFTQDQYFFSLPEKSHVRHLIGRVE 1662

Query: 711  AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
            A D D G + V+ YS++    S  FS+    G+
Sbjct: 1663 ASDADAGVDGVILYSLE--TPSPFFSVNKTNGN 1693



 Score =  270 bits (661), Expect = 5e-70
 Identities = 231/799 (28%), Positives = 370/799 (46%), Gaps = 72/799 (9%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +++V D ND+SPV E    +  +   + +  T   L+A+D D G N  V ++        
Sbjct: 784  KVHVTDVNDNSPVLEQNPLDIFLSSQSPTNQTAAILRASDPDSGPNGTVTFSFA------ 837

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
              P              Q V  I+  +GA+  +     E    +  L KA DQ  P    
Sbjct: 838  -EP--------------QSVLSINEYTGAIQLQQIPSSEYFPIWLQL-KAVDQGVPAR-- 879

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
              +T  + V  ++  D    FS+  Y   V E+     + V  K  A D+      +I+Y
Sbjct: 880  --TTTGLLVIHMEGEDVRISFSQHLYKGIVPENCEAGTSIVTIKAFAPDS---IRDSIKY 934

Query: 190  AIIGGNTQMQFSIDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            ++  GN    FS+ S SG+V++   K LD+E  +  +L++ A+  G   R   +++ + I
Sbjct: 935  SVFSGNEDGVFSLCSKSGEVTVKEPKFLDFEVRKEVQLIVLAESRG---RKAYSKVAVFI 991

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            +D+ND+ P F  S++Q SVSE     + IV+V A D D G N  + Y++   +  GNV  
Sbjct: 992  QDLNDHPPHFEQSVYQVSVSEGQFYNHHIVQVFATDLDSGSNGLVEYSILSGNQ-GNV-- 1048

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
               +DP SG +  S  LD E  + Y L+V A D G P  S T                F+
Sbjct: 1049 -FQMDPLSGVLTASAILDYEYTSTYSLIVQAMDKGMPRLSDTTVIKIQVTDINDNAPIFL 1107

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYE-ITGGNTRGRFSITSQNGRGLITVA 426
            P +  VE+ E+  PGT V  ++  D D +    +  +   N+  +F+I      G++ + 
Sbjct: 1108 PSE-AVEIVENSLPGTIVTRISVYDVDSNPAFTFSFVKESNSGTKFAI--DRNTGVVVLV 1164

Query: 427  QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
            + LDF++  +Y L +  +D   +++   V +++ D N+  PVF    Y  ++ E  P+G 
Sbjct: 1165 ETLDFEEATKYELQIQISDLVHQTE-GTVTVHVLDVNDNPPVFSQDSYQVTISELVPLGH 1223

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKLLDRETMS 545
             VL + ATD +   N  ITY + S           + F ++P  G I T N +   E  S
Sbjct: 1224 PVLTIVATDVESSEN--ITYRILSS---------SKMFSVDPTNGTIFTINPVFLMERKS 1272

Query: 546  GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
                 V A DGG P L   T VE  + D+N+  P F  + Y  ++ ED  VG ++     
Sbjct: 1273 TIRFLVEASDGGFPDLKAVTLVETEIQDMNNYAPEFAIEYYNLSLSEDTPVGRTLVTFST 1332

Query: 606  TDAD-VGLNGRIHYELDPKDRE-----EGSFVIDPAS----GVIRTNKALDRESVATHDL 655
             D D    N  + Y +   + +     E SF+    S    G +     LDRE+ A+H+L
Sbjct: 1333 IDHDWTRENTHVEYSIISGNSQNNFHVETSFIHSEYSYKQVGYLVLLHHLDREATASHEL 1392

Query: 656  KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
              +A D G PP SS+  V I++ D++D+PP F S     +I E++P G+ I  + A D D
Sbjct: 1393 VLLAFDHGCPPLSSSATVSIEVLDVDDNPPAFSSLEYYVHIKESTPPGSPIIVVSASDRD 1452

Query: 716  EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL- 774
             G +A V Y +  G++   F LE + G     L  +  LDYE    K+ L ++A+     
Sbjct: 1453 VGSHAEVSYYLTSGNEKQHFCLEEKTG----VLSLIKPLDYEE-TIKFILTVQASDEERK 1507

Query: 775  -WNDVRVEILVTDVNDNAP 792
             ++   V + V D ND+AP
Sbjct: 1508 HFSFAIVFVNVLDDNDHAP 1526



 Score =  266 bits (652), Expect = 6e-69
 Identities = 223/779 (28%), Positives = 363/779 (46%), Gaps = 50/779 (6%)

Query: 96  SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSE--- 152
           SG L++  +LD E+ A + V V  +D  SP     S+T  +HV++ D NDN P F +   
Sbjct: 2   SGELISWVALDHEQRAHHQVAVLVSDHGSPPR---SATTLVHVSVTDINDNRPYFPQCLA 58

Query: 153 -KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSL 211
            K   V V E   V  N ++  + A D D G N+ + Y++   ++   F ID+ SG++  
Sbjct: 59  GKELYVKVLEGQPV--NMLVTTVFAKDLDEGNNAEVIYSVSSEDSSDHFKIDANSGEIRT 116

Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271
            + L  +   SYR+ + A D G P       + I +  ++        ++    + EN+ 
Sbjct: 117 TRVLSRDYGPSYRMTVIASDQGVPPLQGQAVINIQVIPLSKGRTVISQNIRHLVIPENLK 176

Query: 272 IGYSIVRVQAYD-ADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA 330
               +  +++ D        +L +++   D  G+ +    +D  +G ++ S +LD E  +
Sbjct: 177 PTKVMSLIKSPDHLQRQHGGKLHFSIAADDKDGHFE----VDSSTGDLFLSKELDYEMMS 232

Query: 331 KYQL-LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389
            Y L +VT     +PP ++T                F      + + E+ P GT V    
Sbjct: 233 HYLLRVVTKDHSRNPPVNSTVFLSVAVEDQNDHSPSFREEFIVISVPENTPVGTLVHIFN 292

Query: 390 ATDADE---DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD- 445
           A D D    ++R+ Y I   N  G          G +    PLD ++    VLTV+A+D 
Sbjct: 293 AKDGDGSFLNSRIQYFIE-ANHPGMNPFLIHPSSGTLVTTSPLDRERVPTVVLTVTASDQ 351

Query: 446 ----SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501
               +  R  + M ++ I D N+++P F + P  A V EDA +G+ V  ++A D D G N
Sbjct: 352 AVNVTDRRLRSLMAKVVILDVNDHSPTFTSFP-IAHVREDAAVGSLVHHITAQDPDAGRN 410

Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL 561
            ++T+S+ S   NE +A     F+++  +G +TT   LD E  S ++LT+ A DGG P+L
Sbjct: 411 GRVTFSILS--GNENMA-----FMLDESSGFLTTASPLDYEIKSQHILTLLALDGGTPTL 463

Query: 562 SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621
           S +  + I+V+DVND  PVFKQ LY A++ E+   G  V++V A D D G+N ++ +E+ 
Sbjct: 464 SSSQTLTITVLDVNDEAPVFKQHLYEASVKENQNPGEFVTRVEAVDRDSGINSKLQFEIM 523

Query: 622 PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681
           P       F I+  +G + T   LDRE      L+ +  DGG P  S T ++   + D N
Sbjct: 524 P-GASFMLFQINSDTGEVVTAATLDREVQEVLTLRVLVHDGGAPALSGTTVILCTVRDEN 582

Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741
           D  P          + EN   G  +    A D D G N  V Y I  G+    F++    
Sbjct: 583 DHAPQIVVPRDDIEVLENQEPG-LVYTFLASDMDAGSNGAVTYHIIDGNTDEYFAVNEMS 641

Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQ 798
           G    EL T   LD E     + LVI  +   SPP  +  ++++ V D ND++P     Q
Sbjct: 642 G----ELSTTRALDREEV-SNFTLVILCSDLGSPPQSSTAQLQVRVLDDNDHSPSFPRLQ 696

Query: 799 IIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNT 857
              +  +D   VG    V +  AD  + L  + +        L++E++G+ T+ P   T
Sbjct: 697 YQASVREDA-QVGTTVLVLS-SADEDEGLNGQTMYS------LVHESSGAFTIDPVAGT 747



 Score =  256 bits (628), Expect = 5e-66
 Identities = 202/706 (28%), Positives = 325/706 (46%), Gaps = 44/706 (6%)

Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL---- 261
           SG++     LD+EQ   +++ +   D GSP RS TT + +++ D+NDN P F   L    
Sbjct: 2   SGELISWVALDHEQRAHHQVAVLVSDHGSPPRSATTLVHVSVTDINDNRPYFPQCLAGKE 61

Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321
               V E  P+   +  V A D DEG NAE+ Y+++ +D + +      ID  SG + T+
Sbjct: 62  LYVKVLEGQPVNMLVTTVFAKDLDEGNNAEVIYSVSSEDSSDH----FKIDANSGEIRTT 117

Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381
             L R+    Y++ V A+D G PP    A                      + + E+  P
Sbjct: 118 RVLSRDYGPSYRMTVIASDQGVPPLQGQAVINIQVIPLSKGRTVISQNIRHLVIPENLKP 177

Query: 382 GTPVVTLTAT----DADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437
            T V++L  +          +LH+ I   +  G F + S  G   + +++ LD++    Y
Sbjct: 178 -TKVMSLIKSPDHLQRQHGGKLHFSIAADDKDGHFEVDSSTGD--LFLSKELDYEMMSHY 234

Query: 438 VLTVSATDSGGR---SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494
           +L V   D       + T  + + + D N+++P F       SV E+ P+GT V + +A 
Sbjct: 235 LLRVVTKDHSRNPPVNSTVFLSVAVEDQNDHSPSFREEFIVISVPENTPVGTLVHIFNAK 294

Query: 495 DSDVG-INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553
           D D   +N++I Y +      EA       F+I+P +G + T   LDRE +   +LTVTA
Sbjct: 295 DGDGSFLNSRIQYFI------EANHPGMNPFLIHPSSGTLVTTSPLDRERVPTVVLTVTA 348

Query: 554 RDGGVPSLSD----TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
            D  V +++D    +   ++ ++DVND+ P F      A++ EDA VG+ V  + A D D
Sbjct: 349 SDQAV-NVTDRRLRSLMAKVVILDVNDHSPTF-TSFPIAHVREDAAVGSLVHHITAQDPD 406

Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669
            G NGR+ + +     E  +F++D +SG + T   LD E  + H L  +A+DGGTP  SS
Sbjct: 407 AGRNGRVTFSI-LSGNENMAFMLDESSGFLTTASPLDYEIKSQHILTLLALDGGTPTLSS 465

Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729
           +  + I + D+ND  PVF+       + EN   G  +  + A D D G N+ + + I  G
Sbjct: 466 SQTLTITVLDVNDEAPVFKQHLYEASVKENQNPGEFVTRVEAVDRDSGINSKLQFEIMPG 525

Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYESPR--KKYELVIRAASPPLWNDVRVEILVTDV 787
                F +     SD  E+VT   LD E         LV    +P L     +   V D 
Sbjct: 526 ASFMLFQI----NSDTGEVVTAATLDREVQEVLTLRVLVHDGGAPALSGTTVILCTVRDE 581

Query: 788 NDNAP---VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNE 844
           ND+AP   V +D   +  N +    V  F      DA     + Y I+ GN      +NE
Sbjct: 582 NDHAPQIVVPRDDIEVLENQEPGL-VYTF-LASDMDAGSNGAVTYHIIDGNTDEYFAVNE 639

Query: 845 TTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITE 889
            +G ++ +  L+       T+ +  +D G     +  QL VR++ +
Sbjct: 640 MSGELSTTRALDREEVSNFTLVILCSDLGSPPQSSTAQLQVRVLDD 685



 Score =  241 bits (589), Expect = 3e-61
 Identities = 180/648 (27%), Positives = 317/648 (48%), Gaps = 52/648 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I V D ND++P+F +      + E +  GT V  +   D D    +   +T   V    
Sbjct: 1093 KIQVTDINDNAPIF-LPSEAVEIVENSLPGTIVTRISVYDVD----SNPAFTFSFVKESN 1147

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
               +                F ID  +G ++   +LD E+  +Y + ++ +D    +  +
Sbjct: 1148 SGTK----------------FAIDRNTGVVVLVETLDFEEATKYELQIQISD----LVHQ 1187

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
               T T+HV  +D NDN P FS+ +Y V++ E + +  +PV+  I ATD +   N  I Y
Sbjct: 1188 TEGTVTVHV--LDVNDNPPVFSQDSYQVTISELVPL-GHPVLT-IVATDVESSEN--ITY 1241

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDY-EQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
             I+  ++   FS+D  +G +  +  +   E+  + R ++ A DGG P     T +   I+
Sbjct: 1242 RIL--SSSKMFSVDPTNGTIFTINPVFLMERKSTIRFLVEASDGGFPDLKAVTLVETEIQ 1299

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD---EGVNAELTYTMTDKDYTGNV 305
            D+N+ AP F    +  S+SE+ P+G ++V     D D   E  + E +    +     +V
Sbjct: 1300 DMNNYAPEFAIEYYNLSLSEDTPVGRTLVTFSTIDHDWTRENTHVEYSIISGNSQNNFHV 1359

Query: 306  DLPITIDPRS----GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
            +        S    G++     LDRE  A ++L++ A D G PP S++AT          
Sbjct: 1360 ETSFIHSEYSYKQVGYLVLLHHLDREATASHELVLLAFDHGCPPLSSSATVSIEVLDVDD 1419

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNG 419
                F   +Y V + E  PPG+P++ ++A+D D  +   + Y +T GN +  F +  + G
Sbjct: 1420 NPPAFSSLEYYVHIKESTPPGSPIIVVSASDRDVGSHAEVSYYLTSGNEKQHFCLEEKTG 1479

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSGGRSDT-AMVQINITDANNYAPVFENAPYTASV 478
              ++++ +PLD+++  +++LTV A+D   +  + A+V +N+ D N++AP F       +V
Sbjct: 1480 --VLSLIKPLDYEETIKFILTVQASDEERKHFSFAIVFVNVLDDNDHAPQFMFPNLNCAV 1537

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ-FVINPQTGAITTNK 537
             E+ P+ +T+  V+A D D G    +TYS+ S         HD   F+I+P TG I+  +
Sbjct: 1538 PENLPVFSTICSVNALDFDAGPYGDMTYSIVSPCPLPHEMPHDHNFFLIDPLTGDISAQQ 1597

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
            +LD E  + Y L V A+D    + S    V++  +D  + EP+F Q  Y  ++ E + V 
Sbjct: 1598 VLDYENDNKYCLIVQAKDKADSTASVVVWVDVEGID--EFEPIFTQDQYFFSLPEKSHVR 1655

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645
              + +V A+DAD G++G I Y L   +     F ++  +G I  ++AL
Sbjct: 1656 HLIGRVEASDADAGVDGVILYSL---ETPSPFFSVNKTNGNIYLSRAL 1700



 Score =  150 bits (364), Expect = 5e-34
 Identities = 118/428 (27%), Positives = 197/428 (46%), Gaps = 28/428 (6%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTAD 68
            +  + D N+++P F ++ Y  S+ E    G T++T    D D   +N  VEY+I  ++ +
Sbjct: 1295 ETEIQDMNNYAPEFAIEYYNLSLSEDTPVGRTLVTFSTIDHDWTRENTHVEYSI--ISGN 1352

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
            + N               + V       G L+    LDRE  A + +++ A D   P   
Sbjct: 1353 SQNNFHVETSFIHSEYSYKQV-------GYLVLLHHLDREATASHELVLLAFDHGCP--- 1402

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             LSS+AT+ + ++D +DN P FS   Y V + E  +   +P+I  + A+D DVG+++ + 
Sbjct: 1403 PLSSSATVSIEVLDVDDNPPAFSSLEYYVHIKES-TPPGSPIIV-VSASDRDVGSHAEVS 1460

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            Y +  GN +  F ++  +G +SL+K LDYE+   + L ++A D       +   + +N+ 
Sbjct: 1461 YYLTSGNEKQHFCLEEKTGVLSLIKPLDYEETIKFILTVQASD-EERKHFSFAIVFVNVL 1519

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            D ND+AP+F       +V EN+P+  +I  V A D D G   ++TY++       + ++P
Sbjct: 1520 DDNDHAPQFMFPNLNCAVPENLPVFSTICSVNALDFDAGPYGDMTYSIVSPCPLPH-EMP 1578

Query: 309  -----ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
                   IDP +G +     LD E   KY L+V A D  D   +A+              
Sbjct: 1579 HDHNFFLIDPLTGDISAQQVLDYENDNKYCLIVQAKDKAD--STASVVVWVDVEGIDEFE 1636

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRG 421
              F   QY   L E       +  + A+DAD   D  + Y +        FS+   NG  
Sbjct: 1637 PIFTQDQYFFSLPEKSHVRHLIGRVEASDADAGVDGVILYSLE--TPSPFFSVNKTNGNI 1694

Query: 422  LITVAQPL 429
             ++ A PL
Sbjct: 1695 YLSRALPL 1702



 Score = 82.2 bits (194), Expect = 2e-13
 Identities = 61/230 (26%), Positives = 100/230 (43%), Gaps = 11/230 (4%)

Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT- 693
           +SG + +  ALD E  A H +  +  D G+PP+S+T +VH+ + DIND+ P F   CL  
Sbjct: 1   SSGELISWVALDHEQRAHHQVAVLVSDHGSPPRSATTLVHVSVTDINDNRPYF-PQCLAG 59

Query: 694 --FYIS--ENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV 749
              Y+   E  P+   +  + A D DEG NA V YS+   D S+ F ++   G  +   V
Sbjct: 60  KELYVKVLEGQPVNMLVTTVFAKDLDEGNNAEVIYSVSSEDSSDHFKIDANSGEIRTTRV 119

Query: 750 TMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKD---FQIIFNNYKD 806
             +  DY    +   +      PPL     + I V  ++    V+       +I  N K 
Sbjct: 120 --LSRDYGPSYRMTVIASDQGVPPLQGQAVINIQVIPLSKGRTVISQNIRHLVIPENLKP 177

Query: 807 CFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
              +               KL + I + +      ++ +TG + LS +L+
Sbjct: 178 TKVMSLIKSPDHLQRQHGGKLHFSIAADDKDGHFEVDSSTGDLFLSKELD 227


>UniRef50_UPI000069E6F8 Cluster: dachsous 2 isoform 1; n=1; Xenopus
            tropicalis|Rep: dachsous 2 isoform 1 - Xenopus tropicalis
          Length = 2689

 Score =  349 bits (859), Expect = 5e-94
 Identities = 271/871 (31%), Positives = 407/871 (46%), Gaps = 57/871 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIG-KNAEVEYTIELVTADT 69
            I + D NDH P+F        V E    GT + T KA D+D   +N+++ Y+        
Sbjct: 824  IYIEDTNDHRPLFPDHIIVLGVDEDVPVGTLLYTFKANDKDGSLENSKIRYS-------- 875

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            LN               ++ F I    GAL T   LDRE    + + V ATDQA+ +S R
Sbjct: 876  LNTHGTG----------ENPFFIHEWEGALTTANELDREMAESFVLTVTATDQAANISHR 925

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
              ++  + + I D NDN PQ        SV ED  +    ++ +I A D D G N  I +
Sbjct: 926  RCTSVIVRIVIQDINDNSPQVLSLP-VASVMEDAQI--GSLVHRIVAKDPDEGRNGKIGF 982

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             I  GN Q  F +D  +G ++L   +D E    Y L I A D G PS S T  L I++ D
Sbjct: 983  HIKEGNAQQVFLLDETTGWLTLHSEIDREVQDHYILTILALDDGIPSLSVTQTLTISLID 1042

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            VND  P F   L++ +V EN   G  +++V A D D G N+ LTY +      G+     
Sbjct: 1043 VNDKTPTFTQGLYEAAVPENQDPGLYVIKVAAVDYDLGNNSVLTYEILPGPAYGH----F 1098

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             I+P +G + T+   DRE Q ++ + V   DGG PP S+T                 +  
Sbjct: 1099 RINPETGELVTTTVFDREQQDRFIIEVLVKDGGSPPLSSTTAILCSILDENDHTPEVLFP 1158

Query: 370  QYEVELAEDEPPGTPVVTLTA-TDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
              E+ + E++  G     L A  DA  + RLH++IT GN  G F+I + +G+  +   + 
Sbjct: 1159 DVEIRVPENQDLGIIHTVLAADKDAGNNGRLHFQITDGNMGGYFAINNTSGQ--LWATRT 1216

Query: 429  LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
            LD +    + +TV   D G   RS  A ++I + D N+  P F  + Y   V ED  IG+
Sbjct: 1217 LDREDFSSFTITVECHDLGTPHRSTIAKLRITVLDENDNPPTFPKSQYRTLVREDLKIGS 1276

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
             VL + A+D+D G+N +I YSL  +            F +N  TG I T + LDRE    
Sbjct: 1277 AVLKLQASDADEGLNKEIMYSLIDDTQG--------AFTVNRTTGNIVTIRTLDREVKHQ 1328

Query: 547  YLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
            Y+  V A D  + +  S T  V + + DVNDN PVF +      I    L   +++ V A
Sbjct: 1329 YVFRVVASDCSLRNPKSATVKVLVYIEDVNDNSPVFTENPIHVLISPKVLENKTIANVHA 1388

Query: 606  TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
            +D D+GLNG + Y L    +    F I    G ++    L  E  +T  L+  A D G P
Sbjct: 1389 SDVDLGLNGTVVYNL---IKSNPFFYITQEKGEVKLQMPLPAEFSST-VLQVQASDLGIP 1444

Query: 666  PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA--HDPDEGPNAVVH 723
            P + T +V I I+ + D    F  +     I ENS  GT +  ++A  H+P++    ++H
Sbjct: 1445 PNTVTGLVIIDIQGL-DKEIAFVHNFYEAIILENSEAGTLVVTVKALYHNPND---EIIH 1500

Query: 724  YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEIL 783
            Y++  GD   +F+L    G    +   +  LD+E+   K+ L+I A S       RV + 
Sbjct: 1501 YTVFSGDKKGAFNLNPITGDLMVKEPRL--LDFETV-NKFNLIISAESSQYTTYCRVTVF 1557

Query: 784  VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDAD--VTDKLQYRILSGNNANLI 840
            + D NDNAPV      I +   +  P   F  +V A D D  +  ++ Y I+SGN  N  
Sbjct: 1558 IQDDNDNAPVFDQLDYI-SFVSEGQPFNTFVIQVFAADGDSGINGQIDYSIISGNENNAF 1616

Query: 841  LLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            +L+   G ++ +  L+  +     + V  TD
Sbjct: 1617 VLDSRHGILSTNVILDREIKSSYRLTVQATD 1647



 Score =  297 bits (728), Expect = 4e-78
 Identities = 248/813 (30%), Positives = 386/813 (47%), Gaps = 70/813 (8%)

Query: 13   VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72
            + D ND++PVF+   Y + V EG    T V+ + A D D G N +++Y+I  ++ +  N 
Sbjct: 1558 IQDDNDNAPVFDQLDYISFVSEGQPFNTFVIQVFAADGDSGINGQIDYSI--ISGNENN- 1614

Query: 73   EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132
                             F +D R G L T   LDRE  + Y + V+ATD+ SP     SS
Sbjct: 1615 ----------------AFVLDSRHGILSTNVILDREIKSSYRLTVQATDRGSP---SCSS 1655

Query: 133  TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192
            T+ + V I+D NDN P       TV + ED +   +  I  I A D D+  + +  +   
Sbjct: 1656 TSVVTVLILDINDNAPTIPPMN-TVLIAEDAAPGYS--IGSISANDVDLRPDLSYTFTE- 1711

Query: 193  GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252
             GN  ++F+ID  SG ++L ++LDYE+   + L I+A D    + +   +L+I + DVND
Sbjct: 1712 NGNPGLKFAIDRYSGIITLTESLDYEESSQHCLRIQASDSVYHTEA---ELIIKVLDVND 1768

Query: 253  NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312
            N P F  ++++ ++ E       I  V A D D  +   +TY +      G V    +  
Sbjct: 1769 NPPVFTQNIYKVALPELTESNTFITTVSATDQDSEIYGPITYKIISP-LKGFVINTTSGK 1827

Query: 313  PRSGWVYTSGQLDRETQA-KYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371
             RS  VYT   L +E ++ + Q+L+ A D G PP ++TA               F    Y
Sbjct: 1828 LRS--VYTDMPLGKENKSTEIQILIVAMDNGSPPLTSTAMLSVTILDVNNYAPTFSEDIY 1885

Query: 372  EVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQNG--------R 420
             V ++ED   G  V+TLTA D D   ++  + + I GGN    F + S            
Sbjct: 1886 YVNVSEDALVGDTVLTLTAMDLDWSPKNALIDFSIIGGNAHNLFYLESSEVLSHIPFIVT 1945

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASV 478
            G + + QPLDF+    + L +  ++ G    + +A + INI D+N+  P+F N+ Y  SV
Sbjct: 1946 GKLIINQPLDFEVASAHRLDIFVSNQGFPPLNSSATIIINILDSNDNPPLFSNSEYHVSV 2005

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             E  P+ +T++++SATDSD G NA ITYS+ S        + +  F I+ Q G +T  + 
Sbjct: 2006 REHYPLKSTIIIISATDSDTGENADITYSIVS-------GNDENVFTIDAQNGTVTLVQP 2058

Query: 539  LDRETMSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
            LD E    Y LT+ ARDG G         + I+V+D ND  P F  Q  + NI E+    
Sbjct: 2059 LDYEETMKYSLTLQARDGHGSKRNVAFALLSITVLDENDFAPKFLFQSQSCNIYENVPFF 2118

Query: 598  TSVSQVGATDADVGLNGRIHYELDPK----DREEGSFVIDPASGVIRTNKALDRESVATH 653
            + V  V A D D G  G + + +        +   +F+ID  +G I T   +D E    H
Sbjct: 2119 SPVCSVNAIDLDSGQYGILSFSIQSSCFNDQQHPATFLIDSLTGDIYTKHRIDYEMQERH 2178

Query: 654  DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713
             L     D      S+ V+V+I IE  ++  PVF  +   F + E +  G  IG++ A D
Sbjct: 2179 CLVVQVKDRSE--SSACVLVYIDIEGEDEFQPVFYQNQYLFDLPEENIGGQEIGKVGALD 2236

Query: 714  PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV---IRAA 770
             DEG + VVHY ++    S  FS+    G     L   V     + RK  E +   ++A 
Sbjct: 2237 NDEGLDGVVHYFLE--KPSQFFSINMTSG--MIYLTRTVHKKRSNTRKNDEFIEFHVKAH 2292

Query: 771  SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN 803
            SP    D +  +    VN ++  ++D+ ++  N
Sbjct: 2293 SPKF--DSKSAMCTVRVNISS-ALEDYPVMSAN 2322



 Score =  296 bits (726), Expect = 6e-78
 Identities = 248/851 (29%), Positives = 399/851 (46%), Gaps = 72/851 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I+++D ND +P F    YEA+V E    G  V+ + A D D+G N+ + Y I        
Sbjct: 1038 ISLIDVNDKTPTFTQGLYEAAVPENQDPGLYVIKVAAVDYDLGNNSVLTYEIL------- 1090

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             P  A              FRI+  +G L+T    DRE+  R+ + V   D  SP    L
Sbjct: 1091 -PGPAYGH-----------FRINPETGELVTTTVFDREQQDRFIIEVLVKDGGSPP---L 1135

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            SST  I  +I+D+ND+ P+       + V E+    D  +I  + A D D G N  + + 
Sbjct: 1136 SSTTAILCSILDENDHTPEVLFPDVEIRVPEN---QDLGIIHTVLAADKDAGNNGRLHFQ 1192

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I  GN    F+I++ SG +   +TLD E   S+ + +   D G+P RS   +L I + D 
Sbjct: 1193 ITDGNMGGYFAINNTSGQLWATRTLDREDFSSFTITVECHDLGTPHRSTIAKLRITVLDE 1252

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN P F  S ++  V E++ IG +++++QA DADEG+N E+ Y++ D D  G      T
Sbjct: 1253 NDNPPTFPKSQYRTLVREDLKIGSAVLKLQASDADEGLNKEIMYSLID-DTQG----AFT 1307

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPPRSATATXXXXXXXXXXXXXXFMPG 369
            ++  +G + T   LDRE + +Y   V A+D     P+SAT                F   
Sbjct: 1308 VNRTTGNIVTIRTLDREVKHQYVFRVVASDCSLRNPKSATVKVLVYIEDVNDNSPVFTEN 1367

Query: 370  QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
               V ++        +  + A+D D   +  + Y +   N    F IT + G   + +  
Sbjct: 1368 PIHVLISPKVLENKTIANVHASDVDLGLNGTVVYNLIKSNP--FFYITQEKGEVKLQMPL 1425

Query: 428  PLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
            P +F      VL V A+D G    + T +V I+I   +       N  Y A + E++  G
Sbjct: 1426 PAEFSST---VLQVQASDLGIPPNTVTGLVIIDIQGLDKEIAFVHNF-YEAIILENSEAG 1481

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ--FVINPQTGAITTN--KLLDR 541
            T V+ V A          + ++ + EI +  V   D++  F +NP TG +     +LLD 
Sbjct: 1482 TLVVTVKA----------LYHNPNDEIIHYTVFSGDKKGAFNLNPITGDLMVKEPRLLDF 1531

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
            ET++ + L ++A      +    T   + + D NDN PVF Q  Y + + E     T V 
Sbjct: 1532 ETVNKFNLIISAESSQYTTYCRVT---VFIQDDNDNAPVFDQLDYISFVSEGQPFNTFVI 1588

Query: 602  QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
            QV A D D G+NG+I Y +     E  +FV+D   G++ TN  LDRE  +++ L   A D
Sbjct: 1589 QVFAADGDSGINGQIDYSI-ISGNENNAFVLDSRHGILSTNVILDREIKSSYRLTVQATD 1647

Query: 662  GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
             G+P  SST +V + I DIND+ P       T  I+E++  G +IG I A+D D  P+  
Sbjct: 1648 RGSPSCSSTSVVTVLILDINDNAPTI-PPMNTVLIAEDAAPGYSIGSISANDVDLRPDLS 1706

Query: 722  VHYSIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVIRAASPPLWNDVRV 780
              ++ + G+    F+++   G     ++T+ + LDYE    ++ L I+A+      +  +
Sbjct: 1707 YTFT-ENGNPGLKFAIDRYSG-----IITLTESLDYEE-SSQHCLRIQASDSVYHTEAEL 1759

Query: 781  EILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNAN 838
             I V DVNDN PV     +++      +             D+++   + Y+I+S     
Sbjct: 1760 IIKVLDVNDNPPVFTQNIYKVALPELTESNTFITTVSATDQDSEIYGPITYKIISPLKG- 1818

Query: 839  LILLNETTGSM 849
              ++N T+G +
Sbjct: 1819 -FVINTTSGKL 1828



 Score =  275 bits (675), Expect = 1e-71
 Identities = 260/903 (28%), Positives = 422/903 (46%), Gaps = 76/903 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I VLD ND+ P F   QY   VRE    G+ VL L+A+D D G N E+ Y++     DT
Sbjct: 1246 RITVLDENDNPPTFPKSQYRTLVREDLKIGSAVLKLQASDADEGLNKEIMYSL---IDDT 1302

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                             Q  F ++  +G ++T  +LDRE   +Y   V A+D +  + + 
Sbjct: 1303 -----------------QGAFTVNRTTGNIVTIRTLDREVKHQYVFRVVASDCS--LRNP 1343

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             S+T  + V I D NDN P F+E    V +     V +N  IA + A+D D+G N  + Y
Sbjct: 1344 KSATVKVLVYIEDVNDNSPVFTENPIHVLISP--KVLENKTIANVHASDVDLGLNGTVVY 1401

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             +I  N    F I    G+V L   L  E   S  L ++A D G P  + T  ++I+I+ 
Sbjct: 1402 NLIKSNPF--FYITQEKGEVKLQMPLPAE-FSSTVLQVQASDLGIPPNTVTGLVIIDIQG 1458

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL-P 308
            + D    F  + ++  + EN   G  +V V+A   +   +  + YT+   D  G  +L P
Sbjct: 1459 L-DKEIAFVHNFYEAIILENSEAGTLVVTVKALYHNPN-DEIIHYTVFSGDKKGAFNLNP 1516

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
            IT D     V     LD ET  K+ L+++A        +                  F  
Sbjct: 1517 ITGDLM---VKEPRLLDFETVNKFNLIISAESS---QYTTYCRVTVFIQDDNDNAPVFDQ 1570

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
              Y   ++E +P  T V+ + A D D   + ++ Y I  GN    F + S++G  +++  
Sbjct: 1571 LDYISFVSEGQPFNTFVIQVFAADGDSGINGQIDYSIISGNENNAFVLDSRHG--ILSTN 1628

Query: 427  QPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
              LD + +  Y LTV ATD G  S   T++V + I D N+ AP       T  + EDA  
Sbjct: 1629 VILDREIKSSYRLTVQATDRGSPSCSSTSVVTVLILDINDNAPTIPPMN-TVLIAEDAAP 1687

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            G ++  +SA D D+  +   T++   E  N  +     +F I+  +G IT  + LD E  
Sbjct: 1688 GYSIGSISANDVDLRPDLSYTFT---ENGNPGL-----KFAIDRYSGIITLTESLDYEES 1739

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
            S + L + A D    +     ++ I V+DVNDN PVF Q +Y   + E     T ++ V 
Sbjct: 1740 SQHCLRIQASDSVYHT---EAELIIKVLDVNDNPPVFTQNIYKVALPELTESNTFITTVS 1796

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR---TNKALDRESVATH-DLKAVAI 660
            ATD D  + G I Y++    +    FVI+  SG +R   T+  L +E+ +T   +  VA+
Sbjct: 1797 ATDQDSEIYGPITYKIISPLK---GFVINTTSGKLRSVYTDMPLGKENKSTEIQILIVAM 1853

Query: 661  DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP-N 719
            D G+PP +ST ++ + I D+N+  P F  D     +SE++ +G T+  + A D D  P N
Sbjct: 1854 DNGSPPLTSTAMLSVTILDVNNYAPTFSEDIYYVNVSEDALVGDTVLTLTAMDLDWSPKN 1913

Query: 720  AVVHYSIKGGDDSNSFSLETRQGSDK------AELVTMVDLDYE--SPRKKYELVIRAAS 771
            A++ +SI GG+  N F LE+ +           +L+    LD+E  S  +    V     
Sbjct: 1914 ALIDFSIIGGNAHNLFYLESSEVLSHIPFIVTGKLIINQPLDFEVASAHRLDIFVSNQGF 1973

Query: 772  PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPAYDADVTDK--LQ 828
            PPL +   + I + D NDN P+  + +   +  ++ +P+      + A D+D  +   + 
Sbjct: 1974 PPLNSSATIIINILDSNDNPPLFSNSEYHVS-VREHYPLKSTIIIISATDSDTGENADIT 2032

Query: 829  YRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIK--AMMQLSVRL 886
            Y I+SGN+ N+  ++   G++TL   L+       ++ +   DG    +  A   LS+ +
Sbjct: 2033 YSIVSGNDENVFTIDAQNGTVTLVQPLDYEETMKYSLTLQARDGHGSKRNVAFALLSITV 2092

Query: 887  ITE 889
            + E
Sbjct: 2093 LDE 2095



 Score =  268 bits (656), Expect = 2e-69
 Identities = 243/846 (28%), Positives = 391/846 (46%), Gaps = 82/846 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + + D ND+SPVF        +        T+  + A+D D+G N  V Y   L+ +   
Sbjct: 1352 VYIEDVNDNSPVFTENPIHVLISPKVLENKTIANVHASDVDLGLNGTVVYN--LIKS--- 1406

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVL-VKATDQASPVSDR 129
            NP                 F I    G +  +  L  E  +  TVL V+A+D   P +  
Sbjct: 1407 NP----------------FFYITQEKGEVKLQMPLPAEFSS--TVLQVQASDLGIPPN-- 1446

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             + T  + ++I    D    F    Y   + E+       ++  +KA   +   +  I Y
Sbjct: 1447 -TVTGLVIIDI-QGLDKEIAFVHNFYEAIILENSEA--GTLVVTVKALYHNPN-DEIIHY 1501

Query: 190  AIIGGNTQMQFSIDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
             +  G+ +  F+++ ++GD+ +   + LD+E V  + L+I A+   S   +   ++ + I
Sbjct: 1502 TVFSGDKKGAFNLNPITGDLMVKEPRLLDFETVNKFNLIISAE---SSQYTTYCRVTVFI 1558

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            +D NDNAP F    +   VSE  P    +++V A D D G+N ++ Y++     +GN + 
Sbjct: 1559 QDDNDNAPVFDQLDYISFVSEGQPFNTFVIQVFAADGDSGINGQIDYSII----SGNENN 1614

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
               +D R G + T+  LDRE ++ Y+L V ATD G P  S+T+                +
Sbjct: 1615 AFVLDSRHGILSTNVILDREIKSSYRLTVQATDRGSPSCSSTSVVTVLILDINDNAPT-I 1673

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT-GGNTRGRFSITSQNGRGLITVA 426
            P    V +AED  PG  + +++A D D    L Y  T  GN   +F+I   +G  +IT+ 
Sbjct: 1674 PPMNTVLIAEDAAPGYSIGSISANDVDLRPDLSYTFTENGNPGLKFAIDRYSG--IITLT 1731

Query: 427  QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
            + LD+++  ++ L + A+DS   ++  ++ I + D N+  PVF    Y  ++ E     T
Sbjct: 1732 ESLDYEESSQHCLRIQASDSVYHTEAELI-IKVLDVNDNPPVFTQNIYKVALPELTESNT 1790

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG---AITTNKLLDRET 543
             +  VSATD D  I   ITY + S +           FVIN  +G   ++ T+  L +E 
Sbjct: 1791 FITTVSATDQDSEIYGPITYKIISPLKG---------FVINTTSGKLRSVYTDMPLGKEN 1841

Query: 544  MSGYL-LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
             S  + + + A D G P L+ T  + ++++DVN+  P F + +Y  N+ EDALVG +V  
Sbjct: 1842 KSTEIQILIVAMDNGSPPLTSTAMLSVTILDVNNYAPTFSEDIYYVNVSEDALVGDTVLT 1901

Query: 603  VGATDADVG----------LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652
            + A D D            + G  H     +  E  S +    +G +  N+ LD E  + 
Sbjct: 1902 LTAMDLDWSPKNALIDFSIIGGNAHNLFYLESSEVLSHIPFIVTGKLIINQPLDFEVASA 1961

Query: 653  HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
            H L     + G PP +S+  + I I D ND+PP+F +      + E+ P+ +TI  I A 
Sbjct: 1962 HRLDIFVSNQGFPPLNSSATIIINILDSNDNPPLFSNSEYHVSVREHYPLKSTIIIISAT 2021

Query: 713  DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVIRA-- 769
            D D G NA + YSI  G+D N F+++ + G+     VT+V  LDYE    KY L ++A  
Sbjct: 2022 DSDTGENADITYSIVSGNDENVFTIDAQNGT-----VTLVQPLDYEE-TMKYSLTLQARD 2075

Query: 770  --ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKL 827
               S        + I V D ND AP    FQ    N  +  P   F  V + +A   D  
Sbjct: 2076 GHGSKRNVAFALLSITVLDENDFAPKFL-FQSQSCNIYENVPF--FSPVCSVNAIDLDSG 2132

Query: 828  QYRILS 833
            QY ILS
Sbjct: 2133 QYGILS 2138



 Score =  245 bits (600), Expect = 1e-62
 Identities = 249/922 (27%), Positives = 413/922 (44%), Gaps = 90/922 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++++ D ND++PVFE   Y  S+      GT +L + A D+D G   +V Y  EL++ + 
Sbjct: 76  RVDIEDINDNAPVFEPSTYVTSISSHTQPGTEILNVMAIDRDEGLFGDVTY--ELLSGEH 133

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                              +F ID  +G +   + L   + +  ++ V A D+    S  
Sbjct: 134 -----------------SSLFTIDSSTGIIYLISVLSHLEDSWVSLSVAARDKGGLTS-- 174

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            +  AT+ +NI+        F +  YT  + ED  V     +  +KA +  + +   + Y
Sbjct: 175 -AVNATVTMNILKTATAPAIFEKSRYTFVIAED--VPKGSAVGTVKARE-PLNSLEPVSY 230

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            II GN    F+I +  G +   K LD+E +    L +++Q G S S  ++TQ+ + I D
Sbjct: 231 RIISGNVHQMFTIHTQFGIIRTQKELDFESLPLVVLTVQSQLGSS-SVFSSTQVNVTITD 289

Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            NDN P F +   + SV +N   G +I   QA D D G N +++Y++  +    N DL I
Sbjct: 290 ANDNPPVFSSENERISVHQNTSPGTAIYIAQATDLDSGFNGQISYSIASE----NQDLFI 345

Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT-XXXXXXXXXXXXXXFMP 368
            ID   G +Y +  L   +  ++ LL+ A D G P  S+  T               F  
Sbjct: 346 -IDSTFGVLYLNATL--SSVREHVLLILAEDYGHPVISSLLTLTIIVEQNKQSNTLSFFN 402

Query: 369 GQYEVELAEDEPPGTPVVTL---TATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV 425
             +  E++E  P  + ++ +   T       + + Y ++       F I      G I +
Sbjct: 403 LVHRTEISETLPINSHILQVKAYTRNTQSTSSEIMYSLSPTIDSAPFRI--HQSTGWIFL 460

Query: 426 AQPLDFKQERRYVLTVSATDSGGRSD----TAMVQINITDANNYAPVFENAPYTASVFED 481
            + +D+++ + + L V AT SG R D    TA + + I D N+ +P F++A +  +V E 
Sbjct: 461 RRSVDYEKSKTHNLKVVAT-SGDREDQQTATASIIVKILDENDNSPSFDHATHFFTVNES 519

Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
                 +  + A D D G N Q++Y L SE +N         F+I+ +TG I     LDR
Sbjct: 520 PVPHGVIGSIQAFDRDSGNNGQLSYFLLSEGNN---------FLISSKTGEIINCASLDR 570

Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ-----QLYTANIMEDALV 596
           E  + + L V   D G P  + TT V I V D+NDN+P F Q     QL+   +ME    
Sbjct: 571 ERKAHHELNVLVTDNGTPRRNATTTVYIIVADLNDNKPYFPQLASGKQLH-VKVMEGQAE 629

Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
              V+ V A D D G NG + Y     D   G FVI+ ++G I T KAL  +    + L 
Sbjct: 630 PMLVATVYAKDPDAGNNGTVVY-FFASDESFGQFVINASTGEIWTTKALTAKLRPQYGLT 688

Query: 657 AVAIDGGTPPQSSTVIVHIKI---EDINDSPPVFE--------SDCLTFYISENSPIGTT 705
             A D GTPP     +V+I+I    ++   PP           S   T  + EN+     
Sbjct: 689 VTASDQGTPPLVEHTVVNIEITITAEVLQHPPKVSFKEKTKTVSKIKTMKVPENTYPTQK 748

Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765
           IG + +H+     ++ +HY +   ++   F +++  G    ++     LD+E+    Y L
Sbjct: 749 IGSVISHEEAFLLSSKMHYRLANEENKGHFVVDSLTG----DVYVSRHLDFET-ISYYGL 803

Query: 766 -----VIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAY 819
                 I   SPP  + V + I + D ND+ P+  D  I+    +D  PVG       A 
Sbjct: 804 SIDIQEIDKISPPNLS-VFLTIYIEDTNDHRPLFPDHIIVLGVDED-VPVGTLLYTFKAN 861

Query: 820 DAD---VTDKLQYRI-LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE 875
           D D      K++Y +   G   N   ++E  G++T + +L+  + +   + V+ TD    
Sbjct: 862 DKDGSLENSKIRYSLNTHGTGENPFFIHEWEGALTTANELDREMAESFVLTVTATDQAAN 921

Query: 876 I--KAMMQLSVRLITEEMLLNS 895
           I  +    + VR++ +++  NS
Sbjct: 922 ISHRRCTSVIVRIVIQDINDNS 943



 Score =  245 bits (600), Expect = 1e-62
 Identities = 243/875 (27%), Positives = 396/875 (45%), Gaps = 73/875 (8%)

Query: 86   VQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145
            V  +F I  + G + T+  LD E +     LV  T Q+   S  + S+  ++V I D ND
Sbjct: 237  VHQMFTIHTQFGIIRTQKELDFESLP----LVVLTVQSQLGSSSVFSSTQVNVTITDAND 292

Query: 146  NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205
            N P FS +   +SV ++ S      IA+  ATD D G N  I Y+I   N  + F IDS 
Sbjct: 293  NPPVFSSENERISVHQNTSPGTAIYIAQ--ATDLDSGFNGQISYSIASENQDL-FIIDST 349

Query: 206  SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI-RDVNDNAPRFYTSLFQE 264
             G + L  TL    VR + L+I A+D G P  S+   L I + ++   N   F+  + + 
Sbjct: 350  FGVLYLNATLS--SVREHVLLILAEDYGHPVISSLLTLTIIVEQNKQSNTLSFFNLVHRT 407

Query: 265  SVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYTGNVD-LPITIDPRSGWVYTSG 322
             +SE +PI   I++V+AY  + +  ++E+ Y+++       +D  P  I   +GW++   
Sbjct: 408  EISETLPINSHILQVKAYTRNTQSTSSEIMYSLSP-----TIDSAPFRIHQSTGWIFLRR 462

Query: 323  QLDRETQAKYQLLVTATDGG-DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381
             +D E    + L V AT G  +  ++ATA+              F    +   + E   P
Sbjct: 463  SVDYEKSKTHNLKVVATSGDREDQQTATASIIVKILDENDNSPSFDHATHFFTVNESPVP 522

Query: 382  GTPVVTLTATDADEDNR---LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYV 438
               + ++ A D D  N     ++ ++ GN    F I+S+ G  +I  A  LD +++  + 
Sbjct: 523  HGVIGSIQAFDRDSGNNGQLSYFLLSEGNN---FLISSKTGE-IINCAS-LDRERKAHHE 577

Query: 439  LTVSATDSGG--RSDTAMVQINITDANNYAPVF----ENAPYTASVFEDAPIGTTVLVVS 492
            L V  TD+G   R+ T  V I + D N+  P F            V E       V  V 
Sbjct: 578  LNVLVTDNGTPRRNATTTVYIIVADLNDNKPYFPQLASGKQLHVKVMEGQAEPMLVATVY 637

Query: 493  ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552
            A D D G N  + Y  +S+ S         QFVIN  TG I T K L  +    Y LTVT
Sbjct: 638  AKDPDAGNNGTVVYFFASDESFG-------QFVINASTGEIWTTKALTAKLRPQYGLTVT 690

Query: 553  ARDGGVPSLSDTTDVEISVV---DVNDNEPV--FKQQ------LYTANIMEDALVGTSVS 601
            A D G P L + T V I +    +V  + P   FK++      + T  + E+      + 
Sbjct: 691  ASDQGTPPLVEHTVVNIEITITAEVLQHPPKVSFKEKTKTVSKIKTMKVPENTYPTQKIG 750

Query: 602  QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA--VA 659
             V + +    L+ ++HY L   +  +G FV+D  +G +  ++ LD E+++ + L      
Sbjct: 751  SVISHEEAFLLSSKMHYRL-ANEENKGHFVVDSLTGDVYVSRHLDFETISYYGLSIDIQE 809

Query: 660  IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG-P 718
            ID  +PP  S V + I IED ND  P+F    +   + E+ P+GT +   +A+D D    
Sbjct: 810  IDKISPPNLS-VFLTIYIEDTNDHRPLFPDHIIVLGVDEDVPVGTLLYTFKANDKDGSLE 868

Query: 719  NAVVHYSIK-GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA------S 771
            N+ + YS+   G   N F +   +G+    L T  +LD E   + + L + A       S
Sbjct: 869  NSKIRYSLNTHGTGENPFFIHEWEGA----LTTANELDREM-AESFVLTVTATDQAANIS 923

Query: 772  PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQY 829
                  V V I++ D+NDN+P +    +  +  +D        R+ A D D     K+ +
Sbjct: 924  HRRCTSVIVRIVIQDINDNSPQVLSLPVA-SVMEDAQIGSLVHRIVAKDPDEGRNGKIGF 982

Query: 830  RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV-SVTDGVNEIKAMMQLSVRLIT 888
             I  GN   + LL+ETTG +TL  +++  V     + + ++ DG+  +     L++ LI 
Sbjct: 983  HIKEGNAQQVFLLDETTGWLTLHSEIDREVQDHYILTILALDDGIPSLSVTQTLTISLID 1042

Query: 889  EEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAI 923
                  + T  L +    +   P  G ++  +AA+
Sbjct: 1043 VNDKTPTFTQGLYEAAVPENQDP--GLYVIKVAAV 1075



 Score =  235 bits (576), Expect = 1e-59
 Identities = 190/633 (30%), Positives = 294/633 (46%), Gaps = 39/633 (6%)

Query: 173 KIKATDADVGANSAIRYAIIGG--NTQ--MQFSIDSLSGDVSLVKTLDYEQ-VRSYRLVI 227
           K+KATDAD G    I Y++  G  NT+    F ID  SG + +   +D E    SY L++
Sbjct: 2   KVKATDADSGPFGQIHYSVYDGFHNTKESQSFRIDPDSGRICVSNDIDKESGPTSYDLLV 61

Query: 228 RAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG 287
           +A+D G  S     +  ++I D+NDNAP F  S +  S+S +   G  I+ V A D DEG
Sbjct: 62  KAEDEGGLSAQAFVR--VDIEDINDNAPVFEPSTYVTSISSHTQPGTEILNVMAIDRDEG 119

Query: 288 VNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRS 347
           +  ++TY +   +++       TID  +G +Y    L     +   L V A D G    +
Sbjct: 120 LFGDVTYELLSGEHSS----LFTIDSSTGIIYLISVLSHLEDSWVSLSVAARDKGGLTSA 175

Query: 348 ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD-ADEDNRLHYEITGG 406
             AT              F   +Y   +AED P G+ V T+ A +  +    + Y I  G
Sbjct: 176 VNATVTMNILKTATAPAIFEKSRYTFVIAEDVPKGSAVGTVKAREPLNSLEPVSYRIISG 235

Query: 407 NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV-SATDSGGRSDTAMVQINITDANNY 465
           N    F+I +Q   G+I   + LDF+     VLTV S   S     +  V + ITDAN+ 
Sbjct: 236 NVHQMFTIHTQ--FGIIRTQKELDFESLPLVVLTVQSQLGSSSVFSSTQVNVTITDANDN 293

Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525
            PVF +     SV ++   GT + +  ATD D G N QI+YS++SE        +   F+
Sbjct: 294 PPVFSSENERISVHQNTSPGTAIYIAQATDLDSGFNGQISYSIASE--------NQDLFI 345

Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN--DNEPVFKQ 583
           I+   G +  N  L   ++  ++L + A D G P +S    + I +V+ N   N   F  
Sbjct: 346 IDSTFGVLYLNATL--SSVREHVLLILAEDYGHPVISSLLTLTI-IVEQNKQSNTLSFFN 402

Query: 584 QLYTANIMEDALVGTSVSQVGA-TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642
            ++   I E   + + + QV A T      +  I Y L P   +   F I  ++G I   
Sbjct: 403 LVHRTEISETLPINSHILQVKAYTRNTQSTSSEIMYSLSP-TIDSAPFRIHQSTGWIFLR 461

Query: 643 KALDRESVATHDLKAVAIDGG-TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701
           +++D E   TH+LK VA  G     Q++T  + +KI D ND+ P F+     F ++E+  
Sbjct: 462 RSVDYEKSKTHNLKVVATSGDREDQQTATASIIVKILDENDNSPSFDHATHFFTVNESPV 521

Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPR 760
               IG I+A D D G N  + Y +    + N+F + ++ G    E++    LD E    
Sbjct: 522 PHGVIGSIQAFDRDSGNNGQLSYFLL--SEGNNFLISSKTG----EIINCASLDRERKAH 575

Query: 761 KKYELVIRAASPPLWN-DVRVEILVTDVNDNAP 792
            +  +++     P  N    V I+V D+NDN P
Sbjct: 576 HELNVLVTDNGTPRRNATTTVYIIVADLNDNKP 608



 Score =  235 bits (575), Expect = 1e-59
 Identities = 240/891 (26%), Positives = 388/891 (43%), Gaps = 74/891 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + + D ND+ PVF  +    SV +  S GT +   +ATD D G N ++ Y+I        
Sbjct: 285  VTITDANDNPPVFSSENERISVHQNTSPGTAIYIAQATDLDSGFNGQISYSI-------- 336

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                            QD+F ID   G L   A+L    V  + +L+ A D   PV   +
Sbjct: 337  ------------ASENQDLFIIDSTFGVLYLNATLS--SVREHVLLILAEDYGHPV---I 379

Query: 131  SSTATIHVNIIDDN--DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKA-TDADVGANSAI 187
            SS  T+ + I++ N   N   F    +   + E + +  N  I ++KA T      +S I
Sbjct: 380  SSLLTLTI-IVEQNKQSNTLSFFNLVHRTEISETLPI--NSHILQVKAYTRNTQSTSSEI 436

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT-QLLIN 246
             Y++        F I   +G + L +++DYE+ +++ L + A  G    +   T  +++ 
Sbjct: 437  MYSLSPTIDSAPFRIHQSTGWIFLRRSVDYEKSKTHNLKVVATSGDREDQQTATASIIVK 496

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIV-RVQAYDADEGVNAELTYTMTDKDYTGNV 305
            I D NDN+P F  +    +V+E+ P+ + ++  +QA+D D G N +L+Y +  +   GN 
Sbjct: 497  ILDENDNSPSFDHATHFFTVNES-PVPHGVIGSIQAFDRDSGNNGQLSYFLLSE---GNN 552

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
             L   I  ++G +     LDRE +A ++L V  TD G P R+AT T              
Sbjct: 553  FL---ISSKTGEIINCASLDRERKAHHELNVLVTDNGTPRRNATTTVYIIVADLNDNKPY 609

Query: 366  FMP----GQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNG 419
            F       Q  V++ E +     V T+ A D D  N   + Y      + G+F I +  G
Sbjct: 610  FPQLASGKQLHVKVMEGQAEPMLVATVYAKDPDAGNNGTVVYFFASDESFGQFVINASTG 669

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479
               I   + L  K   +Y LTV+A+D G         +NI +    A V ++ P  +   
Sbjct: 670  E--IWTTKALTAKLRPQYGLTVTASDQGTPPLVEHTVVNI-EITITAEVLQHPPKVSFKE 726

Query: 480  EDAPIGT--TVLVVSATDSDVGINAQITYS----LSSEISNEAVAHHDQ-QFVINPQTGA 532
            +   +    T+ V   T     I + I++     LSS++        ++  FV++  TG 
Sbjct: 727  KTKTVSKIKTMKVPENTYPTQKIGSVISHEEAFLLSSKMHYRLANEENKGHFVVDSLTGD 786

Query: 533  ITTNKLLDRETMSGYLLTVTARDG---GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589
            +  ++ LD ET+S Y L++  ++      P+LS    + I + D ND+ P+F   +    
Sbjct: 787  VYVSRHLDFETISYYGLSIDIQEIDKISPPNLS--VFLTIYIEDTNDHRPLFPDHIIVLG 844

Query: 590  IMEDALVGTSVSQVGATDADVGL-NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648
            + ED  VGT +    A D D  L N +I Y L+     E  F I    G + T   LDRE
Sbjct: 845  VDEDVPVGTLLYTFKANDKDGSLENSKIRYSLNTHGTGENPFFIHEWEGALTTANELDRE 904

Query: 649  SVATHDLKAVAIDGG---TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
               +  L   A D     +  + ++VIV I I+DIND+ P   S  +   + E++ IG+ 
Sbjct: 905  MAESFVLTVTATDQAANISHRRCTSVIVRIVIQDINDNSPQVLSLPVAS-VMEDAQIGSL 963

Query: 706  IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765
            +  I A DPDEG N  + + IK G+    F L+   G     L + +D + +       L
Sbjct: 964  VHRIVAKDPDEGRNGKIGFHIKEGNAQQVFLLDETTGW--LTLHSEIDREVQDHYILTIL 1021

Query: 766  VIRAASPPLWNDVRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPAYDADV 823
             +    P L     + I + DVND  P      ++      +D  P     +V A D D+
Sbjct: 1022 ALDDGIPSLSVTQTLTISLIDVNDKTPTFTQGLYEAAVPENQD--PGLYVIKVAAVDYDL 1079

Query: 824  TDK--LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
             +   L Y IL G       +N  TG +  +   +        +EV V DG
Sbjct: 1080 GNNSVLTYEILPGPAYGHFRINPETGELVTTTVFDREQQDRFIIEVLVKDG 1130



 Score =  196 bits (478), Expect = 7e-48
 Identities = 206/796 (25%), Positives = 339/796 (42%), Gaps = 63/796 (7%)

Query: 90  FRIDGRSGALLTRASLDREK-VARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           FRID  SG +     +D+E     Y +LVKA D+       LS+ A + V+I D NDN P
Sbjct: 33  FRIDPDSGRICVSNDIDKESGPTSYDLLVKAEDEGG-----LSAQAFVRVDIEDINDNAP 87

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
            F   TY  S+           I  + A D D G    + Y ++ G     F+IDS +G 
Sbjct: 88  VFEPSTYVTSISSHTQ--PGTEILNVMAIDRDEGLFGDVTYELLSGEHSSLFTIDSSTGI 145

Query: 209 VSLVKTLDYEQVRSYRLVIRAQD-GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
           + L+  L + +     L + A+D GG  S  N T + +NI         F  S +   ++
Sbjct: 146 IYLISVLSHLEDSWVSLSVAARDKGGLTSAVNAT-VTMNILKTATAPAIFEKSRYTFVIA 204

Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
           E+VP G ++  V+A +    +   ++Y +     +GNV    TI  + G + T  +LD E
Sbjct: 205 EDVPKGSAVGTVKAREPLNSLEP-VSYRII----SGNVHQMFTIHTQFGIIRTQKELDFE 259

Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387
           +     L V +  G     S+T                F      + + ++  PGT +  
Sbjct: 260 SLPLVVLTVQSQLGSSSVFSSTQVNVTITDANDNPPV-FSSENERISVHQNTSPGTAIYI 318

Query: 388 LTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445
             ATD D   + ++ Y I   N +  F I S  G   +           R +VL + A D
Sbjct: 319 AQATDLDSGFNGQISYSIASEN-QDLFIIDSTFGVLYLNAT----LSSVREHVLLILAED 373

Query: 446 SGGRSDTAMVQINI-TDANNYAPV--FENAPYTASVFEDAPIGTTVLVVSA-TDSDVGIN 501
            G    ++++ + I  + N  +    F N  +   + E  PI + +L V A T +    +
Sbjct: 374 YGHPVISSLLTLTIIVEQNKQSNTLSFFNLVHRTEISETLPINSHILQVKAYTRNTQSTS 433

Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG-VPS 560
           ++I YSLS  I +         F I+  TG I   + +D E    + L V A  G     
Sbjct: 434 SEIMYSLSPTIDSAP-------FRIHQSTGWIFLRRSVDYEKSKTHNLKVVATSGDREDQ 486

Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620
            + T  + + ++D NDN P F    +   + E  +    +  + A D D G NG++ Y L
Sbjct: 487 QTATASIIVKILDENDNSPSFDHATHFFTVNESPVPHGVIGSIQAFDRDSGNNGQLSYFL 546

Query: 621 DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680
                E  +F+I   +G I    +LDRE  A H+L  +  D GTP +++T  V+I + D+
Sbjct: 547 LS---EGNNFLISSKTGEIINCASLDRERKAHHELNVLVTDNGTPRRNATTTVYIIVADL 603

Query: 681 NDSPPVF----ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736
           ND+ P F        L   + E       +  + A DPD G N  V Y     +    F 
Sbjct: 604 NDNKPYFPQLASGKQLHVKVMEGQAEPMLVATVYAKDPDAGNNGTVVYFFASDESFGQFV 663

Query: 737 LETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWND--VRVEILVT-DVNDN 790
           +    G    E+ T   L  +  R +Y L + A+   +PPL     V +EI +T +V  +
Sbjct: 664 INASTG----EIWTTKALTAKL-RPQYGLTVTASDQGTPPLVEHTVVNIEITITAEVLQH 718

Query: 791 APVM--KDFQIIFNNYK------DCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLI 840
            P +  K+     +  K      + +P    G V +++    ++ K+ YR+ +  N    
Sbjct: 719 PPKVSFKEKTKTVSKIKTMKVPENTYPTQKIGSVISHEEAFLLSSKMHYRLANEENKGHF 778

Query: 841 LLNETTGSMTLSPQLN 856
           +++  TG + +S  L+
Sbjct: 779 VVDSLTGDVYVSRHLD 794



 Score =  189 bits (460), Expect = 1e-45
 Identities = 172/609 (28%), Positives = 273/609 (44%), Gaps = 39/609 (6%)

Query: 277 VRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET-QAKYQLL 335
           ++V+A DAD G   ++ Y++ D  +         IDP SG +  S  +D+E+    Y LL
Sbjct: 1   IKVKATDADSGPFGQIHYSVYDGFHNTKESQSFRIDPDSGRICVSNDIDKESGPTSYDLL 60

Query: 336 VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395
           V A D G    SA A               F P  Y   ++    PGT ++ + A D DE
Sbjct: 61  VKAEDEGG--LSAQAFVRVDIEDINDNAPVFEPSTYVTSISSHTQPGTEILNVMAIDRDE 118

Query: 396 D--NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSD-- 451
                + YE+  G     F+I S    G+I +   L   ++    L+V+A D GG +   
Sbjct: 119 GLFGDVTYELLSGEHSSLFTIDSST--GIIYLISVLSHLEDSWVSLSVAARDKGGLTSAV 176

Query: 452 TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE 511
            A V +NI        +FE + YT  + ED P G+ V  V A +  +     ++Y + S 
Sbjct: 177 NATVTMNILKTATAPAIFEKSRYTFVIAEDVPKGSAVGTVKARE-PLNSLEPVSYRIIS- 234

Query: 512 ISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571
                  +  Q F I+ Q G I T K LD E++   +LTV ++ G   S+  +T V +++
Sbjct: 235 ------GNVHQMFTIHTQFGIIRTQKELDFESLPLVVLTVQSQLGS-SSVFSSTQVNVTI 287

Query: 572 VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631
            D NDN PVF  +    ++ ++   GT++    ATD D G NG+I Y +  ++++   F+
Sbjct: 288 TDANDNPPVFSSENERISVHQNTSPGTAIYIAQATDLDSGFNGQISYSIASENQD--LFI 345

Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV-FESD 690
           ID   GV+  N  L   SV  H L  +A D G P  SS + + I +E    S  + F + 
Sbjct: 346 IDSTFGVLYLNATL--SSVREHVLLILAEDYGHPVISSLLTLTIIVEQNKQSNTLSFFNL 403

Query: 691 CLTFYISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV 749
                ISE  PI + I +++A+  + +  ++ + YS+    DS  F +    G     + 
Sbjct: 404 VHRTEISETLPINSHILQVKAYTRNTQSTSSEIMYSLSPTIDSAPFRIHQSTG----WIF 459

Query: 750 TMVDLDYESPRKKYELVIRAASPPLWND----VRVEILVTDVNDNAPVMKDFQIIFNNYK 805
               +DYE   K + L + A S    +       + + + D NDN+P        F   +
Sbjct: 460 LRRSVDYEK-SKTHNLKVVATSGDREDQQTATASIIVKILDENDNSPSFDHATHFFTVNE 518

Query: 806 DCFPVGPFGRVPAYDADV--TDKLQYRILS-GNNANLILLNETTGSMTLSPQLNTNVPKL 862
              P G  G + A+D D     +L Y +LS GNN    L++  TG +     L+      
Sbjct: 519 SPVPHGVIGSIQAFDRDSGNNGQLSYFLLSEGNN---FLISSKTGEIINCASLDRERKAH 575

Query: 863 ATMEVSVTD 871
             + V VTD
Sbjct: 576 HELNVLVTD 584



 Score =  148 bits (358), Expect = 3e-33
 Identities = 140/518 (27%), Positives = 235/518 (45%), Gaps = 32/518 (6%)

Query: 386 VTLTATDADED--NRLHYEITGG--NTRGRFSITSQNGRGLITVAQPLDFKQ-ERRYVLT 440
           + + ATDAD     ++HY +  G  NT+   S       G I V+  +D +     Y L 
Sbjct: 1   IKVKATDADSGPFGQIHYSVYDGFHNTKESQSFRIDPDSGRICVSNDIDKESGPTSYDLL 60

Query: 441 VSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
           V A D GG S  A V+++I D N+ APVFE + Y  S+      GT +L V A D D G+
Sbjct: 61  VKAEDEGGLSAQAFVRVDIEDINDNAPVFEPSTYVTSISSHTQPGTEILNVMAIDRDEGL 120

Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD-GGVP 559
              +TY L S         H   F I+  TG I    +L     S   L+V ARD GG+ 
Sbjct: 121 FGDVTYELLS-------GEHSSLFTIDSSTGIIYLISVLSHLEDSWVSLSVAARDKGGLT 173

Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619
           S  + T V ++++       +F++  YT  I ED   G++V  V A +    L   + Y 
Sbjct: 174 SAVNAT-VTMNILKTATAPAIFEKSRYTFVIAEDVPKGSAVGTVKAREPLNSLE-PVSYR 231

Query: 620 LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679
           +   +  +  F I    G+IRT K LD ES+    L   +  G +   SST  V++ I D
Sbjct: 232 IISGNVHQ-MFTIHTQFGIIRTQKELDFESLPLVVLTVQSQLGSSSVFSSTQ-VNVTITD 289

Query: 680 INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLET 739
            ND+PPVF S+     + +N+  GT I   +A D D G N  + YSI   ++ + F +++
Sbjct: 290 ANDNPPVFSSENERISVHQNTSPGTAIYIAQATDLDSGFNGQISYSI-ASENQDLFIIDS 348

Query: 740 RQGSDKAELVTMVDLDYESPRKKYELVI-RAASPPLWNDVRVEILVTDVNDNAPVMKDFQ 798
             G      V  ++    S R+   L++      P+ + +    ++ + N  +  +  F 
Sbjct: 349 TFG------VLYLNATLSSVREHVLLILAEDYGHPVISSLLTLTIIVEQNKQSNTLSFFN 402

Query: 799 IIF-NNYKDCFPVGP-FGRVPAYDAD---VTDKLQYRILSGNNANLILLNETTGSMTLSP 853
           ++      +  P+     +V AY  +    + ++ Y +    ++    ++++TG + L  
Sbjct: 403 LVHRTEISETLPINSHILQVKAYTRNTQSTSSEIMYSLSPTIDSAPFRIHQSTGWIFLRR 462

Query: 854 QLNTNVPKLATMEVSVTDGVNEIK--AMMQLSVRLITE 889
            ++    K   ++V  T G  E +  A   + V+++ E
Sbjct: 463 SVDYEKSKTHNLKVVATSGDREDQQTATASIIVKILDE 500


>UniRef50_A7SAP5 Cluster: Predicted protein; n=1; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 4354

 Score =  347 bits (852), Expect = 3e-93
 Identities = 301/981 (30%), Positives = 456/981 (46%), Gaps = 86/981 (8%)

Query: 11   INVLDCNDHSPVF--EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68
            IN++D ND SP F   +    A V E   + T V+++KA D D G       T E+    
Sbjct: 2558 INIIDVNDVSPAFLLAINTRNARVLENKPAPTKVISMKAIDDD-GSEPHRRVTYEMKD-- 2614

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
              NP                 F+ID  +G + T+ +LDRE   +Y V V A D  +  S 
Sbjct: 2615 --NPN----------------FQIDASTGMITTKTTLDREVTPKYDVEVTAKDGVNKES- 2655

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
                 A +++ ++D ND  P F+ K+Y +SV ED  +  +  +  I ATDADVG N+ I 
Sbjct: 2656 -----AILYITVVDQNDQPPVFAPKSYAISVPEDSPIGTS--VLDIYATDADVGENAKIT 2708

Query: 189  YAIIGGNTQMQFSI--DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            Y I  G+ + +FSI    + G++ +   LD+E   SY L + A DG     S+T  + + 
Sbjct: 2709 YFISKGDPEGKFSIVTSPVKGELVVNGKLDFETKSSYTLEVTATDG---KFSDTAVVTVT 2765

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD--KDYTGN 304
            I+DVND  P F + L++  + EN   G  +V V A D D   +  +++++ D  KDY   
Sbjct: 2766 IQDVNDLPPVFSSPLYESRIQENTGPGAGVVMVTASDID---SPTISFSLDDRGKDYFQI 2822

Query: 305  VDLPITIDPRSGWVYT----SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
              +  +  P + WV      S QLDRE        V A DG     +A A          
Sbjct: 2823 TPIRAS-GPGNVWVGDIRTGSKQLDREESPVKVFTVIANDG---KHTAQAEIRVNLTDVN 2878

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-----DNRLHYEITGGNTRGRFSIT 415
                 F    Y   + E++P GT V+ + A D D+     + +L YE+T  +   +FSI 
Sbjct: 2879 DNAPRFPASPYIGYVEENKPSGTSVMYIQAVDDDDPLAGGNAKLSYELTD-SAGDKFSID 2937

Query: 416  SQNGRGLITVAQPLDFKQE-RRYVLTVSATDSGGRSDTAMVQ--INITDANNYAPVFENA 472
              +G  LI      D +Q   ++ + V ATD+G    +A V   I+++DAN++ P F   
Sbjct: 2938 PLSG--LIKTKVTFDREQTPNKFKVRVKATDAGNPRLSASVDGIIHVSDANDHKPKFTEK 2995

Query: 473  PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
             Y  SV E+AP G +VL V+ATD DVG NA+  + +     N+  A     F I+P  G 
Sbjct: 2996 FYRGSVAENAPPGYSVLRVTATDEDVGPNAEFEFVVVQ--GNDPHA-----FYIDPFNGT 3048

Query: 533  ITTNKLLDRETMSGYLLTVTARDGGVPSLS--DTTDVEISVVDVNDNEPVFKQQLYTANI 590
            +  + +LD E    Y +T+T  D G+P L   +T  V I ++D NDN P F  ++Y A++
Sbjct: 3049 VLVSGILDYEKKKEYTITLTVADRGMPPLQGDETAYVVIEILDANDNAPEFIPKIYNASV 3108

Query: 591  MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP-----ASGVIRTNKAL 645
            +ED      V  V A D D G NG   + +DP+   + +F I+P     + G+IRT   L
Sbjct: 3109 LEDVGARQPVLTVTAVDKDSGPNGNFTFAIDPRSDPDDAFTIEPNPNNASIGIIRTRVPL 3168

Query: 646  DRESVATHDLKAVAID-GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
            D+E   +  LK  A D GG   +     V I + D+ND+ P F        I E      
Sbjct: 3169 DQEKTPSFHLKVTATDAGGLQGEGE---VRINVIDVNDNGPWFVPPFFVGQIKEGVSARQ 3225

Query: 705  TIGEIRAHDPDE-GPNAVVHYSIKGGDDSNSFSLE-TRQGSDKAELVTMVDLDYE-SPRK 761
             + +++A+DPD    + V+ +SI  G    +F L+     ++  +L +    D E +P  
Sbjct: 3226 FVTKLKAYDPDAFVKDQVITFSIYNGTVGENFKLDPVSVTNESVDLHSYGVFDREAAPVW 3285

Query: 762  K--YELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY 819
            K   E V      P  N   V + V DVNDNAP      II N Y   F  G  G+    
Sbjct: 3286 KIGIEAVDNVGPKPQKNFTYVYVDVLDVNDNAPKDGSLLIIVNAYDGNFTGGVIGKPYYQ 3345

Query: 820  DADVT-DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKA 878
            D D   D+  Y + S +  +   +NE  G +T +P +      L        D  + + +
Sbjct: 3346 DDDFDGDENTYELNSQSPGSYFRVNEGNGDITAAPMIPMGEYNLKIRVTEKKDSPSTVTS 3405

Query: 879  MMQLSVRLITEEMLLNSITVRLNDM-TAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQ 937
             +++ VR I +E + N + V   DM     F+      F D LA+ +  P  +I IFSVQ
Sbjct: 3406 SVRVLVRRIDKEAVDNGVAVEFTDMRKVGYFVGDYYKGFEDVLASTLGVPTGDIKIFSVQ 3465

Query: 938  DDTDVTGNILNVSFSARRPDA 958
               D  G  + V F+    D+
Sbjct: 3466 KAHD-NGLAVVVFFTVAAKDS 3485



 Score =  320 bits (785), Expect = 5e-85
 Identities = 284/955 (29%), Positives = 447/955 (46%), Gaps = 84/955 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++NV+D NDH P F  + Y  SV     +G++++T++A D DIG NA+V Y +       
Sbjct: 888  EVNVIDVNDHKPEFLQESYWLSVPSSTPAGSSLVTVQAEDMDIGTNAQVRYEL------- 940

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            L  E++                I   +  L T ++L      RY +L++A+D A+   + 
Sbjct: 941  LRQENSERF-------------ILNDNNQLSTASTLTPN--VRYQLLIRASDSAT--RNP 983

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             S+   ++V++   +++   F + +Y  ++ ED S   N ++   KAT +  G++S I Y
Sbjct: 984  SSAQVPVYVSVYSPSESPIVFDKSSYNQNLPEDSSA--NTLVFTAKATRS--GSSSGITY 1039

Query: 190  AIIGGNTQM---QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ-DGGSPSRSNTTQLLI 245
             ++GG  Q+    FSI   +G V L+K LD+E    + + +RA+  GG+   ++     +
Sbjct: 1040 ELVGGYKQIGEAMFSIKPDTGQVYLIKKLDFETKSYFPIAVRAKYSGGAIELASEVVAKV 1099

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQ---AYDADEGVNAELTYTMTDKDYT 302
             I DVNDN PRF    F ES    V   +S    Q   A DAD G   E+TY +     T
Sbjct: 1100 TIVDVNDNGPRF---AFHESSKTVVIDSFSAKDTQLARALDADSGSLGEVTYGIDGGRST 1156

Query: 303  GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPPRSATATXXXXXXXXXX 361
             N  LP  I+ ++G ++ + ++     + Y ++V ATDG  D  +               
Sbjct: 1157 SN--LPFNINVKTGMIFATREILYTQGSSYIIIVVATDGATDGSQKIQKFTVNVQVLDTP 1214

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421
                F    Y   + E    G  V T+ A  +  +  L Y    GN    F +   NG G
Sbjct: 1215 RPPSFPQKTYSAPVTETAGVGDTVTTVRAVYSKPNAFLKYTFVSGNEDNTFCV---NGFG 1271

Query: 422  LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
            +I+VA+ LD ++   Y L +  T  G   D   V +N+TD N+ AP F +A Y  S+ E 
Sbjct: 1272 IISVAKSLDREKVAGYTLGMRVT-LGQHVDDTTVYVNLTDINDDAPHFTSAIYRRSIKEG 1330

Query: 482  APIGTTVLV-VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
                T +L  V A D D G N +I YS+ S +  +     D+ F I+  TG ITT   LD
Sbjct: 1331 LAEDTEILPPVIAVDHDFGSNGKILYSILSGVHPD----WDKYFNIDSATGKITTKMTLD 1386

Query: 541  RETMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
             ET   + L + A D G P  LS    V+I V+D NDN PVF    Y A I   A+ GTS
Sbjct: 1387 YETHKSHTLFIRAEDNGSPKRLSGIAQVDIDVIDRNDNSPVFAAAFYRAKISLGAVKGTS 1446

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
            V QV ATD D G NG+I Y +  +  EE +F I+   GVI  +K+L   +     LK  A
Sbjct: 1447 VLQVHATDLDSGQNGQITYSI-IQGNEEEAFTIN-EQGVILVDKSLTTVAADKFSLKVEA 1504

Query: 660  IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
             D    P+S +V V I +  + D PP+F    +T Y+ E  P    +  ++A       +
Sbjct: 1505 RDKNASPRSGSVTVEINVY-LPDGPPMFVVSPVTVYVKEGVPANHRVAGVKA-----ATS 1558

Query: 720  AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND-V 778
              + Y++  G+++  F +    GS    L    +LDYE  R++YEL I A      +  V
Sbjct: 1559 EALTYTLLSGNEAGMFRINPSTGS----LDATRELDYEE-RRRYELKIEARDTRDRSAMV 1613

Query: 779  RVEILVTDVNDNAPVMKDF---QIIFNNYKDCFPVG-----PFGRVPAYDADVTDKLQYR 830
             + I+V ++NDN P   D    QI       C P          R+ A+D D  D++ + 
Sbjct: 1614 ELIIIVVNINDNKPTFVDIVDGQIDRKAIGTCSPTDIAEGEVITRLGAFDRD-GDEITF- 1671

Query: 831  ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEE 890
            I+  +  +L  + ++ G +T    +  ++PK+    V   D   E      + VRL+   
Sbjct: 1672 IVPDDVKDLFKI-DSRGVVTAKKPIE-DLPKIYPFNVKALDN-GEPPQETDVKVRLVFVH 1728

Query: 891  MLLNSITVRLN---DMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDV 942
               +   VR+N   D      ++ +  +F +G+ +++   K N   FSV+ + DV
Sbjct: 1729 YRPDQKHVRVNVREDTPTGSVIATVRRYFPNGIVSLLLPEKAN---FSVRANGDV 1780



 Score =  281 bits (690), Expect = 1e-73
 Identities = 262/890 (29%), Positives = 405/890 (45%), Gaps = 85/890 (9%)

Query: 12   NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71
            NV D N++ P F       S+RE     T +  L ATD D G+N ++ Y+IE  ++ TL 
Sbjct: 2237 NVADANNNVPQFT-NCGTVSIRENDPRDTKITQLTATDADRGQNGQITYSIEDASSQTL- 2294

Query: 72   PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV--SDR 129
                              F I+ R+G + +  SLDRE    Y  ++KA D +S    S+R
Sbjct: 2295 ------------------FSIEPRTGVVRSLTSLDRENKDSYNAIIKAEDGSSKQDESER 2336

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            L     + +N+ D NDN P F    Y  SV    S  +   I  ++ATDAD G+N+ I+Y
Sbjct: 2337 LLWYCYLTINVEDVNDNRPYFLAAKYFGSVFS--SAPNGSNILTVQATDADSGSNAKIKY 2394

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQD-----GGSPSRSNTT 241
            A++     + F +DS SG +        L  E  +   L + A+D     G  P +    
Sbjct: 2395 ALLDSAGGL-FRLDS-SGILRTNTNPARLQLETGKKLLLEVSAKDVESIAGTQPGKPTKY 2452

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
               I I   N+  P+F   ++  S++EN+  G ++ R+ A  +     AE++Y   D + 
Sbjct: 2453 TTQIEILVSNEEPPKFSQQVYTASINENMETGSTVTRITATSS---TGAEISYENVDTNP 2509

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
               +   +  D   G++ T  + D E    Y +   A D      S              
Sbjct: 2510 RAKILFRVQPD---GYIITGDRPDYERGTTYNMQFAAKDKKTLLYSTVKVVINIIDVNDV 2566

Query: 362  XXXXFMP-GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG-NTRGRFSITSQNG 419
                 +        + E++P  T V+++ A D D+ +  H  +T        F I +  G
Sbjct: 2567 SPAFLLAINTRNARVLENKPAPTKVISMKAID-DDGSEPHRRVTYEMKDNPNFQIDASTG 2625

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479
              +IT    LD +   +Y + V+A D G   ++A++ I + D N+  PVF    Y  SV 
Sbjct: 2626 --MITTKTTLDREVTPKYDVEVTAKD-GVNKESAILYITVVDQNDQPPVFAPKSYAISVP 2682

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
            ED+PIGT+VL + ATD+DVG NA+ITY +S     +         V +P  G +  N  L
Sbjct: 2683 EDSPIGTSVLDIYATDADVGENAKITYFIS-----KGDPEGKFSIVTSPVKGELVVNGKL 2737

Query: 540  DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
            D ET S Y L VTA DG     SDT  V +++ DVND  PVF   LY + I E+   G  
Sbjct: 2738 DFETKSSYTLEVTATDG---KFSDTAVVTVTIQDVNDLPPVFSSPLYESRIQENTGPGAG 2794

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP--ASGV-------IRT-NKALDRES 649
            V  V A+D D   +  I + LD  DR +  F I P  ASG        IRT +K LDRE 
Sbjct: 2795 VVMVTASDID---SPTISFSLD--DRGKDYFQITPIRASGPGNVWVGDIRTGSKQLDREE 2849

Query: 650  VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
                    +A DG    Q+    + + + D+ND+ P F +     Y+ EN P GT++  I
Sbjct: 2850 SPVKVFTVIANDGKHTAQAE---IRVNLTDVNDNAPRFPASPYIGYVEENKPSGTSVMYI 2906

Query: 710  RAHDPDE---GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV 766
            +A D D+   G NA + Y +      + FS++   G  K    T V  D E    K+++ 
Sbjct: 2907 QAVDDDDPLAGGNAKLSYELT-DSAGDKFSIDPLSGLIK----TKVTFDREQTPNKFKVR 2961

Query: 767  IR---AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV 823
            ++   A +P L   V   I V+D ND+ P   +     +  ++  P     RV A D DV
Sbjct: 2962 VKATDAGNPRLSASVDGIIHVSDANDHKPKFTEKFYRGSVAENAPPGYSVLRVTATDEDV 3021

Query: 824  --TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
                + ++ ++ GN+ +   ++   G++ +S  L+    K  T+ ++V D
Sbjct: 3022 GPNAEFEFVVVQGNDPHAFYIDPFNGTVLVSGILDYEKKKEYTITLTVAD 3071



 Score =  243 bits (594), Expect = 6e-62
 Identities = 251/909 (27%), Positives = 402/909 (44%), Gaps = 92/909 (10%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ VLD ND+ P++  ++  A V   + +G  V  L+A D+D G +  V Y ++  + D 
Sbjct: 1812 EVVVLDVNDNRPIWMERERLARVNTNSRAGAQVYQLEARDEDDGSSGLVGYQLKSPSNDA 1871

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                             Q  F I+ ++  +    SL   K  RY + V A D   P   R
Sbjct: 1872 KRKR---------RSPPQHPFTINPKTRQMEVAGSL---KDQRYDLDVFAFDYGIP---R 1916

Query: 130  LSS-TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            L+S T T++V+        P+FS+ +Y   V ED       ++  I A      + + + 
Sbjct: 1917 LTSDTITLNVDGSAAGQLPPRFSKVSYHFMVSEDAKYLS--LVGIILARSI---SGARLD 1971

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGGSPSRSNTTQLLINI 247
            Y I+ GN   +F I    G + L   LD+E+ ++ Y L ++A +       +T  + I++
Sbjct: 1972 YKIVSGNVGDKF-IAMGDGRILLNSLLDFERDQTQYNLKVKATEQIPDGLDSTVDVKIDV 2030

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE-----LTYTMTDKDYT 302
             + ND+ P F   L+   + E+  +G  +  V A D D   +       LTY++      
Sbjct: 2031 INANDHFPYFDQQLYSVQIPESTAVGVLVQEVTAKDCDCLSSCTCSPGFLTYSIEPSKEQ 2090

Query: 303  GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
            G       IDP +G +  S  LD E Q  + L V ATD G                    
Sbjct: 2091 GG---KFYIDPATGKISVSVALDYEDQRYHLLKVYATDKGKKSFQGLCFVNVTLTNVNDN 2147

Query: 363  XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422
               F+   YE  +AE    G  +  + A DAD D  + Y   GG    +FS+      G+
Sbjct: 2148 RPTFLKSAYEFRVAEGAATGESLAIVVAVDADGD-AVTYSKAGGAL--QFSV--DQSTGV 2202

Query: 423  ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
            IT+   LD   + +Y L V A DSGG + T  V  N+ DANN  P F N   T S+ E+ 
Sbjct: 2203 ITLNSALD-PNKNQYTLQVMAKDSGGLTSTVSVTFNVADANNNVPQFTNCG-TVSIREND 2260

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
            P  T +  ++ATD+D G N QITYS+  + S++ +      F I P+TG + +   LDRE
Sbjct: 2261 PRDTKITQLTATDADRGQNGQITYSI-EDASSQTL------FSIEPRTGVVRSLTSLDRE 2313

Query: 543  TMSGYLLTVTARDGGVPSLSDTTD-------VEISVVDVNDNEPVFKQQLYTANIMEDAL 595
                Y   + A DG   S  D ++       + I+V DVNDN P F    Y  ++   A 
Sbjct: 2314 NKDSYNAIIKAEDGS--SKQDESERLLWYCYLTINVEDVNDNRPYFLAAKYFGSVFSSAP 2371

Query: 596  VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN---KALDRES--- 649
             G+++  V ATDAD G N +I Y L   D   G F +D +SG++RTN     L  E+   
Sbjct: 2372 NGSNILTVQATDADSGSNAKIKYAL--LDSAGGLFRLD-SSGILRTNTNPARLQLETGKK 2428

Query: 650  ----VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
                V+  D++++A  G  P + +     I+I   N+ PP F     T  I+EN   G+T
Sbjct: 2429 LLLEVSAKDVESIA--GTQPGKPTKYTTQIEILVSNEEPPKFSQQVYTASINENMETGST 2486

Query: 706  IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPRKKYE 764
            +  I A        A + Y      D+N  +    +      ++T    DYE       +
Sbjct: 2487 VTRITA---TSSTGAEISYE---NVDTNPRAKILFRVQPDGYIITGDRPDYERGTTYNMQ 2540

Query: 765  LVIRAASPPLWNDVRVEILVTDVNDNAPVM------KDFQIIFNNYKDCFPVGPFGRVPA 818
               +     L++ V+V I + DVND +P        ++ +++ N       +     + A
Sbjct: 2541 FAAKDKKTLLYSTVKVVINIIDVNDVSPAFLLAINTRNARVLENKPAPTKVIS----MKA 2596

Query: 819  YDADVTD---KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE 875
             D D ++   ++ Y +    N     ++ +TG +T    L+  V     +EV+  DGVN+
Sbjct: 2597 IDDDGSEPHRRVTYEMKDNPN---FQIDASTGMITTKTTLDREVTPKYDVEVTAKDGVNK 2653

Query: 876  IKAMMQLSV 884
              A++ ++V
Sbjct: 2654 ESAILYITV 2662



 Score =  241 bits (589), Expect = 3e-61
 Identities = 231/822 (28%), Positives = 378/822 (45%), Gaps = 68/822 (8%)

Query: 97   GALLTRASLDREK-VARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155
            G +L  + LD E+   +Y + VKAT+Q   + D L ST  + +++I+ ND++P F ++ Y
Sbjct: 1989 GRILLNSLLDFERDQTQYNLKVKATEQ---IPDGLDSTVDVKIDVINANDHFPYFDQQLY 2045

Query: 156  TVSVDEDISVTDNPVIAKIKATDADVGANSA-----IRYAIIGGNTQM-QFSIDSLSGDV 209
            +V + E  +V    ++ ++ A D D  ++       + Y+I     Q  +F ID  +G +
Sbjct: 2046 SVQIPESTAV--GVLVQEVTAKDCDCLSSCTCSPGFLTYSIEPSKEQGGKFYIDPATGKI 2103

Query: 210  SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269
            S+   LDYE  R + L + A D G  S      + + + +VNDN P F  S ++  V+E 
Sbjct: 2104 SVSVALDYEDQRYHLLKVYATDKGKKSFQGLCFVNVTLTNVNDNRPTFLKSAYEFRVAEG 2163

Query: 270  VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329
               G S+  V A DAD      +TY+       G   L  ++D  +G +  +  LD   +
Sbjct: 2164 AATGESLAIVVAVDAD---GDAVTYSK-----AGGA-LQFSVDQSTGVITLNSALD-PNK 2213

Query: 330  AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389
             +Y L V A D G    + + T                     V + E++P  T +  LT
Sbjct: 2214 NQYTLQVMAKDSGGLTSTVSVTFNVADANNNVPQ---FTNCGTVSIRENDPRDTKITQLT 2270

Query: 390  ATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447
            ATDAD  ++ ++ Y I   +++  FSI  +   G++     LD + +  Y   + A D  
Sbjct: 2271 ATDADRGQNGQITYSIEDASSQTLFSIEPRT--GVVRSLTSLDRENKDSYNAIIKAEDGS 2328

Query: 448  GRSDTA-------MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
             + D +        + IN+ D N+  P F  A Y  SVF  AP G+ +L V ATD+D G 
Sbjct: 2329 SKQDESERLLWYCYLTINVEDVNDNRPYFLAAKYFGSVFSSAPNGSNILTVQATDADSGS 2388

Query: 501  NAQITYSLSSEISNEAVAHHDQQFVI----NPQTGAITTNKLLDRETMSGYLLTVTARDG 556
            NA+I Y+L    S   +   D   ++    NP    + T K L  E  +  + ++     
Sbjct: 2389 NAKIKYALLD--SAGGLFRLDSSGILRTNTNPARLQLETGKKLLLEVSAKDVESIAGTQP 2446

Query: 557  GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616
            G P+   TT +EI V   N+  P F QQ+YTA+I E+   G++V+++ AT +       I
Sbjct: 2447 GKPT-KYTTQIEILV--SNEEPPKFSQQVYTASINENMETGSTVTRITATSS---TGAEI 2500

Query: 617  HYE-LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675
             YE +D   R +  F + P  G I T    D E   T++++  A D  T    STV V I
Sbjct: 2501 SYENVDTNPRAKILFRVQP-DGYIITGDRPDYERGTTYNMQFAAKDKKT-LLYSTVKVVI 2558

Query: 676  KIEDINDSPPVF--ESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDS 732
             I D+ND  P F    +     + EN P  T +  ++A D D   P+  V Y +K   D+
Sbjct: 2559 NIIDVNDVSPAFLLAINTRNARVLENKPAPTKVISMKAIDDDGSEPHRRVTYEMK---DN 2615

Query: 733  NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP 792
             +F ++   G     + T   LD E    KY++ + A          + I V D ND  P
Sbjct: 2616 PNFQIDASTGM----ITTKTTLDRE-VTPKYDVEVTAKDGVNKESAILYITVVDQNDQPP 2670

Query: 793  VMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTD--KLQYRILSGNNAN--LILLNETTG 847
            V        +  +D  P+G     + A DADV +  K+ Y I  G+      I+ +   G
Sbjct: 2671 VFAPKSYAISVPEDS-PIGTSVLDIYATDADVGENAKITYFISKGDPEGKFSIVTSPVKG 2729

Query: 848  SMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889
             + ++ +L+       T+EV+ TDG     A++ ++++ + +
Sbjct: 2730 ELVVNGKLDFETKSSYTLEVTATDGKFSDTAVVTVTIQDVND 2771



 Score =  221 bits (539), Expect = 3e-55
 Identities = 216/804 (26%), Positives = 348/804 (43%), Gaps = 79/804 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++NV D ND +PVFE  QY  ++ E     T+VL ++ATD+D G N  + Y ++      
Sbjct: 237 RVNVEDANDQTPVFESSQYRETIAENTPIQTSVLRVRATDKDDGTNGGIYYYMK------ 290

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            NP             V   F ID  +G +    +LD     ++T+ + A D+  P   R
Sbjct: 291 -NP-------------VNSYFTIDAITGVIRVAKTLDYNARDKHTLYISARDRGDP--PR 334

Query: 130 LSSTATIHVNI------------IDDNDNY-PQFSEKTYTVSVDEDISVTDNPVIAKIKA 176
            S+ AT+ +++             D  +N  P F +  YT S+ ED        +  ++A
Sbjct: 335 TSAEATVEISLRENIQGWPLPDSADPKENTKPYFPQSRYTFSIREDFP--PKGALLVMRA 392

Query: 177 TDAD-VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS---YRLVIRAQDG 232
            D D +G N  +RY++  GN   +F+ID  SG V+L  ++DYE   +   Y L + A D 
Sbjct: 393 ADNDPIGPNKRLRYSL-SGNGVSKFAIDPESGVVTLTDSVDYENTPNNHVYDLTVTATDQ 451

Query: 233 GSPSRSNTTQLLINIRDV--NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290
           G  S S TTQLLI I+DV  N N+PRF        +SEN+     +  V A D+D   N 
Sbjct: 452 GPGSLSATTQLLIEIQDVDENKNSPRFDPQQAILEISENLKQNSLVTTVSATDSDSVGNP 511

Query: 291 ELTYTMTDKDYTGNVDLPI-TIDPRSGWVYTS-GQLDRETQAKYQLLVTATDGGDPPRSA 348
                       G   L +  +D  +G V  +   LDRE  ++Y L+V A+D    PRS+
Sbjct: 512 SSPDGKVVYSIVGGTGLGVFRVDSNTGEVKVAVPSLDREGTSQYTLVVKASDNATFPRSS 571

Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT 408
                            F    Y  ++ E++P GT V  +   DADE     Y +    T
Sbjct: 572 RLFLMINLLDEDDNFPYFSQPIYIAQVPENQPSGTFVTVVVGRDADEGFNPSYTVI---T 628

Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDAN--NYA 466
            G      +   G+I  ++ LD  +     L V    S   S TA  Q+NIT  +  N  
Sbjct: 629 PG-VPYKIEPSTGVIRTSKSLDQSELSTRELQVIVRVSTAGSKTADGQVNITVISKVNRP 687

Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
           PVF+N PY+  V E+      +  ++A DS   ++  + Y+L+           D  F +
Sbjct: 688 PVFKNTPYSVKVPEEMGPLPNLFCIAAVDS---LSRPVQYTLAPGA--------DGLFEV 736

Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586
           +  +G + T    + E +  Y L + AR   V  ++ +  + + V +  D  P F    Y
Sbjct: 737 DKDSGRLHTKNSFNYENVDRYNLRIEARTSSVQEVA-SASLTVEVTEEKD-LPKFSSDSY 794

Query: 587 TANIMEDALVGTSVSQ-VGATDADVGLNG-RIHYELDPKDREEGSFVIDPASG----VIR 640
              + E A  GT+++  +   D+D   +      E         +F +   SG     ++
Sbjct: 795 QLTVDESAAPGTTLAPGLLIIDSDTSSDQFDCSMEAITSLHTLYNFEVTQQSGRCFLRVQ 854

Query: 641 TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700
               LD    + +     A D       +T  V + + D+ND  P F  +     +  ++
Sbjct: 855 AGGKLDAHLASKYTFNVRATDRNFRNMFATAQVEVNVIDVNDHKPEFLQESYWLSVPSST 914

Query: 701 PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760
           P G+++  ++A D D G NA V Y +   ++S  F L     +D  +L T   L   +P 
Sbjct: 915 PAGSSLVTVQAEDMDIGTNAQVRYELLRQENSERFIL-----NDNNQLSTASTL---TPN 966

Query: 761 KKYELVIRAASPPLWNDVRVEILV 784
            +Y+L+IRA+     N    ++ V
Sbjct: 967 VRYQLLIRASDSATRNPSSAQVPV 990



 Score =  216 bits (527), Expect = 8e-54
 Identities = 226/882 (25%), Positives = 385/882 (43%), Gaps = 78/882 (8%)

Query: 21   PVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTADTLNPEDAXXXX 79
            P F   +Y  S+RE       +L ++A D D IG N  + Y++   + + ++        
Sbjct: 366  PYFPQSRYTFSIREDFPPKGALLVMRAADNDPIGPNKRLRYSL---SGNGVSK------- 415

Query: 80   XXXXXXVQDVFRIDGRSGALLTRASLDREKVAR---YTVLVKATDQASPVSDRLSSTATI 136
                      F ID  SG +    S+D E       Y + V ATDQ  P S   ++   I
Sbjct: 416  ----------FAIDPESGVVTLTDSVDYENTPNNHVYDLTVTATDQG-PGSLSATTQLLI 464

Query: 137  HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSA----IRYAI 191
             +  +D+N N P+F  +   + + E++    N ++  + ATD+D VG  S+    + Y+I
Sbjct: 465  EIQDVDENKNSPRFDPQQAILEISENLK--QNSLVTTVSATDSDSVGNPSSPDGKVVYSI 522

Query: 192  IGGNTQMQFSIDSLSGDVSL-VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            +GG     F +DS +G+V + V +LD E    Y LV++A D  +  RS+   L+IN+ D 
Sbjct: 523  VGGTGLGVFRVDSNTGEVKVAVPSLDREGTSQYTLVVKASDNATFPRSSRLFLMINLLDE 582

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            +DN P F   ++   V EN P G  +  V   DADEG N   +YT+          +P  
Sbjct: 583  DDNFPYFSQPIYIAQVPENQPSGTFVTVVVGRDADEGFNP--SYTVITPG------VPYK 634

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            I+P +G + TS  LD+   +  +L V         ++A                 F    
Sbjct: 635  IEPSTGVIRTSKSLDQSELSTRELQVIVRVSTAGSKTADGQVNITVISKVNRPPVFKNTP 694

Query: 371  YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
            Y V++ E+  P   +  + A D+     + Y +  G   G F +   +GR  +      +
Sbjct: 695  YSVKVPEEMGPLPNLFCIAAVDS-LSRPVQYTLAPG-ADGLFEVDKDSGR--LHTKNSFN 750

Query: 431  FKQERRYVLTVSA-TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
            ++   RY L + A T S     +A + + +T+  +  P F +  Y  +V E A  GTT+ 
Sbjct: 751  YENVDRYNLRIEARTSSVQEVASASLTVEVTEEKDL-PKFSSDSYQLTVDESAAPGTTLA 809

Query: 490  V-VSATDSDVGINAQITYSLSSEISNEAVA--HHDQQFVINPQTGA----ITTNKLLDRE 542
              +   DSD       T S   + S EA+   H    F +  Q+G     +     LD  
Sbjct: 810  PGLLIIDSD-------TSSDQFDCSMEAITSLHTLYNFEVTQQSGRCFLRVQAGGKLDAH 862

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
              S Y   V A D    ++  T  VE++V+DVND++P F Q+ Y  ++      G+S+  
Sbjct: 863  LASKYTFNVRATDRNFRNMFATAQVEVNVIDVNDHKPEFLQESYWLSVPSSTPAGSSLVT 922

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
            V A D D+G N ++ YEL  ++  E  F+++  +  + T   L       + L   A D 
Sbjct: 923  VQAEDMDIGTNAQVRYELLRQENSE-RFILND-NNQLSTASTLTPN--VRYQLLIRASDS 978

Query: 663  GT-PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
             T  P S+ V V++ +   ++SP VF+       + E+S   T +   +A     G ++ 
Sbjct: 979  ATRNPSSAQVPVYVSVYSPSESPIVFDKSSYNQNLPEDSSANTLVFTAKA--TRSGSSSG 1036

Query: 722  VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA----ASPPLWND 777
            + Y + GG      ++ + +  D  ++  +  LD+E+ +  + + +RA     +  L ++
Sbjct: 1037 ITYELVGGYKQIGEAMFSIK-PDTGQVYLIKKLDFET-KSYFPIAVRAKYSGGAIELASE 1094

Query: 778  VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSG- 834
            V  ++ + DVNDN P     +       D F         A DAD     ++ Y I  G 
Sbjct: 1095 VVAKVTIVDVNDNGPRFAFHESSKTVVIDSFSAKDTQLARALDADSGSLGEVTYGIDGGR 1154

Query: 835  NNANL-ILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE 875
            + +NL   +N  TG +  + ++         + V  TDG  +
Sbjct: 1155 STSNLPFNINVKTGMIFATREILYTQGSSYIIIVVATDGATD 1196



 Score =  205 bits (500), Expect = 2e-50
 Identities = 202/718 (28%), Positives = 332/718 (46%), Gaps = 79/718 (11%)

Query: 125 PVSDRLSSTA-TIHVNIIDDNDNYPQFS---EKTYTVSVDEDISVTDNPVIAKIKATDAD 180
           P  + L   A T+ + I+D N+ +P F     + Y   V E     +N ++  ++   A 
Sbjct: 103 PRGETLGGIAITLRITILDVNNFHPVFQLSQGEHYEGFVKE--GTAENTIVEGLEQCHAT 160

Query: 181 VGANSAIR-YAIIGGNTQMQFSIDSL---SGDVS----LVKTLDYEQVRS-----YRLVI 227
               S IR Y+II GN +  F ++++   SG  S    ++KT     VR        L +
Sbjct: 161 DRDTSGIRGYSIISGNEKGYFKVETVQIGSGVTSRKFLVLKTTGKPIVRDDNNPYIMLTV 220

Query: 228 RAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG 287
           +  DGG+PS S T  + +N+ D ND  P F +S ++E+++EN PI  S++RV+A D D+G
Sbjct: 221 QVTDGGNPSHSGTANIRVNVEDANDQTPVFESSQYRETIAENTPIQTSVLRVRATDKDDG 280

Query: 288 VNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR- 346
            N  + Y M +      V+   TID  +G +  +  LD   + K+ L ++A D GDPPR 
Sbjct: 281 TNGGIYYYMKNP-----VNSYFTIDAITGVIRVAKTLDYNARDKHTLYISARDRGDPPRT 335

Query: 347 SATATXX-------------XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393
           SA AT                           F   +Y   + ED PP   ++ + A D 
Sbjct: 336 SAEATVEISLRENIQGWPLPDSADPKENTKPYFPQSRYTFSIREDFPPKGALLVMRAADN 395

Query: 394 D---EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK---QERRYVLTVSATDSG 447
           D    + RL Y ++ GN   +F+I  ++  G++T+   +D++       Y LTV+ATD G
Sbjct: 396 DPIGPNKRLRYSLS-GNGVSKFAIDPES--GVVTLTDSVDYENTPNNHVYDLTVTATDQG 452

Query: 448 GRSDTA----MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VG--- 499
             S +A    +++I   D N  +P F+       + E+    + V  VSATDSD VG   
Sbjct: 453 PGSLSATTQLLIEIQDVDENKNSPRFDPQQAILEISENLKQNSLVTTVSATDSDSVGNPS 512

Query: 500 -INAQITYSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKLLDRETMSGYLLTVTARDGG 557
             + ++ YS+   +    +      F ++  TG +      LDRE  S Y L V A D  
Sbjct: 513 SPDGKVVYSI---VGGTGLG----VFRVDSNTGEVKVAVPSLDREGTSQYTLVVKASDNA 565

Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617
               S    + I+++D +DN P F Q +Y A + E+   GT V+ V   DAD G N   +
Sbjct: 566 TFPRSSRLFLMINLLDEDDNFPYFSQPIYIAQVPENQPSGTFVTVVVGRDADEGFNPS-Y 624

Query: 618 YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
             + P       + I+P++GVIRT+K+LD+  ++T +L+ +        +++   V+I +
Sbjct: 625 TVITP----GVPYKIEPSTGVIRTSKSLDQSELSTRELQVIVRVSTAGSKTADGQVNITV 680

Query: 678 EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL 737
               + PPVF++   +  + E       +  I A D    P   V Y++  G D   F +
Sbjct: 681 ISKVNRPPVFKNTPYSVKVPEEMGPLPNLFCIAAVDSLSRP---VQYTLAPGAD-GLFEV 736

Query: 738 ETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMK 795
           +     D   L T    +YE+   +Y L I A +  +  +V    L  +V +   + K
Sbjct: 737 D----KDSGRLHTKNSFNYENV-DRYNLRIEARTSSV-QEVASASLTVEVTEEKDLPK 788



 Score =  194 bits (474), Expect = 2e-47
 Identities = 230/908 (25%), Positives = 386/908 (42%), Gaps = 104/908 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-LKATDQDIGKNAEVEYTIELVTADT 69
            +N+ D ND +P F    Y  S++EG +  T +L  + A D D G N ++ Y+I       
Sbjct: 1306 VNLTDINDDAPHFTSAIYRRSIKEGLAEDTEILPPVIAVDHDFGSNGKILYSI----LSG 1361

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            ++P+                F ID  +G + T+ +LD E    +T+ ++A D  SP   R
Sbjct: 1362 VHPD------------WDKYFNIDSATGKITTKMTLDYETHKSHTLFIRAEDNGSP--KR 1407

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            LS  A + +++ID NDN P F+   Y   +   +       + ++ ATD D G N  I Y
Sbjct: 1408 LSGIAQVDIDVIDRNDNSPVFAAAFYRAKIS--LGAVKGTSVLQVHATDLDSGQNGQITY 1465

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            +II GN +  F+I+   G + + K+L       + L + A+D  +  RS +  + IN+  
Sbjct: 1466 SIIQGNEEEAFTINE-QGVILVDKSLTTVAADKFSLKVEARDKNASPRSGSVTVEINVY- 1523

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            + D  P F  S     V E VP  + +  V+A  ++      LTYT+     +GN     
Sbjct: 1524 LPDGPPMFVVSPVTVYVKEGVPANHRVAGVKAATSEA-----LTYTLL----SGNEAGMF 1574

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP- 368
             I+P +G +  + +LD E + +Y+L + A D  D  RSA                 F+  
Sbjct: 1575 RINPSTGSLDATRELDYEERRRYELKIEARDTRD--RSAMVELIIIVVNINDNKPTFVDI 1632

Query: 369  --GQYEVELA-----EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421
              GQ + +        D   G  +  L A D D D      I   + +  F I S   RG
Sbjct: 1633 VDGQIDRKAIGTCSPTDIAEGEVITRLGAFDRDGDEITF--IVPDDVKDLFKIDS---RG 1687

Query: 422  LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
            ++T  +P++    + Y   V A D+G       V++ +   + Y P  +      +V ED
Sbjct: 1688 VVTAKKPIE-DLPKIYPFNVKALDNGEPPQETDVKVRLVFVH-YRP--DQKHVRVNVRED 1743

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
             P G+ +  V     +      I   L  E +N +V  +    ++ P          LD 
Sbjct: 1744 TPTGSVIATVRRYFPN-----GIVSLLLPEKANFSVRANGDVILLTP----------LDY 1788

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
            E+   + +TV    G   + ++  DVE+ V+DVNDN P++ ++   A +  ++  G  V 
Sbjct: 1789 ESQQFHRMTVREELG---NQTNDVDVEVVVLDVNDNRPIWMERERLARVNTNSRAGAQVY 1845

Query: 602  QVGATDADVGLNGRIHYEL-----DPKDRE----EGSFVIDPASGVIRTNKALDRESVAT 652
            Q+ A D D G +G + Y+L     D K +     +  F I+P +  +    +L  +    
Sbjct: 1846 QLEARDEDDGSSGLVGYQLKSPSNDAKRKRRSPPQHPFTINPKTRQMEVAGSLKDQ---R 1902

Query: 653  HDLKAVAIDGGTPP-QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711
            +DL   A D G P   S T+ +++        PP F      F +SE++   + +G I A
Sbjct: 1903 YDLDVFAFDYGIPRLTSDTITLNVDGSAAGQLPPRFSKVSYHFMVSEDAKYLSLVGIILA 1962

Query: 712  HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771
                    A + Y I  G+  + F      G  +  L ++  LD+E  + +Y L ++A  
Sbjct: 1963 RSIS---GARLDYKIVSGNVGDKF---IAMGDGRILLNSL--LDFERDQTQYNLKVKATE 2014

Query: 772  ---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDK- 826
                 L + V V+I V + ND+ P   D Q+      +   VG     V A D D     
Sbjct: 2015 QIPDGLDSTVDVKIDVINANDHFPYF-DQQLYSVQIPESTAVGVLVQEVTAKDCDCLSSC 2073

Query: 827  ------LQYRI-LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKA 878
                  L Y I  S        ++  TG +++S  L+    +   ++V  TD G    + 
Sbjct: 2074 TCSPGFLTYSIEPSKEQGGKFYIDPATGKISVSVALDYEDQRYHLLKVYATDKGKKSFQG 2133

Query: 879  MMQLSVRL 886
            +  ++V L
Sbjct: 2134 LCFVNVTL 2141



 Score =  170 bits (413), Expect = 5e-40
 Identities = 202/754 (26%), Positives = 327/754 (43%), Gaps = 75/754 (9%)

Query: 207 GDVSLVKTLDYE--QVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF------- 257
           G V+  + ++YE  +   Y L +  +  G         L I I DVN+  P F       
Sbjct: 77  GHVTSTQEIEYEIGKTNKYDLTVLQRPRGETLGGIAITLRITILDVNNFHPVFQLSQGEH 136

Query: 258 YTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDY--TGNVDLPITIDPR 314
           Y    +E  +EN  I   + +  A D D  G+      +  +K Y     V +   +  R
Sbjct: 137 YEGFVKEGTAENT-IVEGLEQCHATDRDTSGIRGYSIISGNEKGYFKVETVQIGSGVTSR 195

Query: 315 SGWVY-TSGQ-LDRETQAKYQLL-VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371
              V  T+G+ + R+    Y +L V  TDGG+P  S TA               F   QY
Sbjct: 196 KFLVLKTTGKPIVRDDNNPYIMLTVQVTDGGNPSHSGTANIRVNVEDANDQTPVFESSQY 255

Query: 372 EVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
              +AE+ P  T V+ + ATD D+  N   Y          F+I +    G+I VA+ LD
Sbjct: 256 RETIAENTPIQTSVLRVRATDKDDGTNGGIYYYMKNPVNSYFTIDAIT--GVIRVAKTLD 313

Query: 431 FKQERRYVLTVSATDSGG---RSDTAMVQINITD-------------ANNYAPVFENAPY 474
           +    ++ L +SA D G     S  A V+I++ +               N  P F  + Y
Sbjct: 314 YNARDKHTLYISARDRGDPPRTSAEATVEISLRENIQGWPLPDSADPKENTKPYFPQSRY 373

Query: 475 TASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
           T S+ ED P    +LV+ A D+D +G N ++ YSLS         +   +F I+P++G +
Sbjct: 374 TFSIREDFPPKGALLVMRAADNDPIGPNKRLRYSLS--------GNGVSKFAIDPESGVV 425

Query: 534 TTNKLLDRETMSG---YLLTVTARDGGVPSLSDTTD--VEISVVDVNDNEPVFKQQLYTA 588
           T    +D E       Y LTVTA D G  SLS TT   +EI  VD N N P F  Q    
Sbjct: 426 TLTDSVDYENTPNNHVYDLTVTATDQGPGSLSATTQLLIEIQDVDENKNSPRFDPQQAIL 485

Query: 589 NIMEDALVGTSVSQVGATDAD-VG----LNGRIHYELDPKDREEGSFVIDPASGVIRTN- 642
            I E+    + V+ V ATD+D VG     +G++ Y +       G F +D  +G ++   
Sbjct: 486 EISENLKQNSLVTTVSATDSDSVGNPSSPDGKVVYSI-VGGTGLGVFRVDSNTGEVKVAV 544

Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
            +LDRE  + + L   A D  T P+SS + + I + D +D+ P F        + EN P 
Sbjct: 545 PSLDREGTSQYTLVVKASDNATFPRSSRLFLMINLLDEDDNFPYFSQPIYIAQVPENQPS 604

Query: 703 GTTIGEIRAHDPDEGPN---AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759
           GT +  +   D DEG N    V+   +    + ++  + T +  D++EL T         
Sbjct: 605 GTFVTVVVGRDADEGFNPSYTVITPGVPYKIEPSTGVIRTSKSLDQSELST--------- 655

Query: 760 RKKYELVIRAASP-PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA 818
            ++ ++++R ++      D +V I V    +  PV K+        ++  P+     + A
Sbjct: 656 -RELQVIVRVSTAGSKTADGQVNITVISKVNRPPVFKNTPYSVKVPEEMGPLPNLFCIAA 714

Query: 819 YDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN-TNVPKLATMEVSVTDGVNEIK 877
            D+ ++  +QY +  G +  L  +++ +G +      N  NV +      + T  V E+ 
Sbjct: 715 VDS-LSRPVQYTLAPGAD-GLFEVDKDSGRLHTKNSFNYENVDRYNLRIEARTSSVQEV- 771

Query: 878 AMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSP 911
           A   L+V  +TEE  L   +     +T ++  +P
Sbjct: 772 ASASLTVE-VTEEKDLPKFSSDSYQLTVDESAAP 804



 Score =  160 bits (388), Expect = 6e-37
 Identities = 111/344 (32%), Positives = 166/344 (48%), Gaps = 39/344 (11%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVT 66
            ++N+ D ND++P F    Y   V E   SGT+V+ ++A D D    G NA++ Y +    
Sbjct: 2871 RVNLTDVNDNAPRFPASPYIGYVEENKPSGTSVMYIQAVDDDDPLAGGNAKLSYEL---- 2926

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA-RYTVLVKATDQASP 125
                                 D F ID  SG + T+ + DRE+   ++ V VKATD  +P
Sbjct: 2927 ----------------TDSAGDKFSIDPLSGLIKTKVTFDREQTPNKFKVRVKATDAGNP 2970

Query: 126  VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
               RLS++    +++ D ND+ P+F+EK Y  SV E  +      + ++ ATD DVG N+
Sbjct: 2971 ---RLSASVDGIIHVSDANDHKPKFTEKFYRGSVAE--NAPPGYSVLRVTATDEDVGPNA 3025

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQL 243
               + ++ GN    F ID  +G V +   LDYE+ + Y + +   D G P      T  +
Sbjct: 3026 EFEFVVVQGNDPHAFYIDPFNGTVLVSGILDYEKKKEYTITLTVADRGMPPLQGDETAYV 3085

Query: 244  LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
            +I I D NDNAP F   ++  SV E+V     ++ V A D D G N   T+ +   D   
Sbjct: 3086 VIEILDANDNAPEFIPKIYNASVLEDVGARQPVLTVTAVDKDSGPNGNFTFAI---DPRS 3142

Query: 304  NVDLPITIDPRS-----GWVYTSGQLDRETQAKYQLLVTATDGG 342
            + D   TI+P       G + T   LD+E    + L VTATD G
Sbjct: 3143 DPDDAFTIEPNPNNASIGIIRTRVPLDQEKTPSFHLKVTATDAG 3186



 Score = 87.0 bits (206), Expect = 7e-15
 Identities = 81/271 (29%), Positives = 112/271 (41%), Gaps = 30/271 (11%)

Query: 1089 CQG--CSIDAAYTTAVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLY-- 1144
            C G  C     Y   +CE+  R+F  +S++  P L       L+ +F T+T  GLL+Y  
Sbjct: 3599 CPGFVCKCPTGYHGPLCEMTTRTFYGNSYIWLPKLMTYSLSDLEFEFMTKTADGLLVYQG 3658

Query: 1145 ---NGRYNERHDFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEI 1201
                G  N   DF+A+ L      RGG   L  S  L     ++     + DG WHTV++
Sbjct: 3659 PEREGANNGLKDFIAVVL------RGGRVELFVSLGLDPVTVKMDKGPRLDDGEWHTVQV 3712

Query: 1202 EYFNRTITMILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHR--FLDLT 1259
                + I +I+D C   L L    D           RK     C +      R  FLD  
Sbjct: 3713 LRNMKDIEIIIDRCSTAL-LEHKPD-----GTVVENRK----SCHVYGRMLGRSVFLDGF 3762

Query: 1260 GPLQIGGLPNIPSSF-QVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCS 1318
            GPLQIGG+ N    F  +    F GC+ +   +H   DL + +       GC +  S C 
Sbjct: 3763 GPLQIGGVSNPNMDFPDIPYTGFKGCVRNIKDNHNLYDLKNPLKVVNAPEGC-QLASACP 3821

Query: 1319 SAPCYNGAECSDLW-DTYICDCKEGHTGKDC 1348
               C N   C  L     IC C  G++GK C
Sbjct: 3822 E--CKNDGYCEPLMARDSICVCNPGYSGKHC 3850



 Score = 37.9 bits (84), Expect = 4.0
 Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 9/85 (10%)

Query: 1477 SDVGFFEGCIQDVRIGTAQSLLNRPTV---RENVRDGCQSRADCMLSICPPYSKCVTSWD 1533
            S +G F GCI    +  A ++ + P++   R+NV DGC     C+ + C     CV +  
Sbjct: 4063 SVLGDFGGCIAGTSVNGA-NMESDPSIKVHRQNVLDGCP----CLSNFCANGGTCVDAMP 4117

Query: 1534 SSTCTCEAGRVGPQCVSACELGPCG 1558
               C C  G  GP C       P G
Sbjct: 4118 PY-CICAPGWTGPLCTIVVTAPPVG 4141


>UniRef50_UPI0000E7FC61 Cluster: PREDICTED: similar to dachsous 1;
            n=3; Gallus gallus|Rep: PREDICTED: similar to dachsous 1
            - Gallus gallus
          Length = 2641

 Score =  345 bits (847), Expect = 1e-92
 Identities = 281/903 (31%), Positives = 418/903 (46%), Gaps = 67/903 (7%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTAD 68
            QI V DCND +P F        V E A +G++V T +A D D +G N++V Y +      
Sbjct: 1385 QILVQDCNDQAPTFPEDPITIVVPENAQAGSSVFTFQALDGDGVGPNSQVRYAL------ 1438

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
             L  E                F +D RSG L    SLDRE VA + ++V+ATDQA  VS 
Sbjct: 1439 -LRQEPPGAP-----------FHLDSRSGLLSLHQSLDREAVASFLLVVEATDQARNVSQ 1486

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            R SS  T  V + D NDN P F      VSV ED       V   + A D D+G N  + 
Sbjct: 1487 RRSSAVTARVFVTDVNDNAPVFLSPA-AVSVTEDRPT--GFVALHVVAQDNDLGENGRVS 1543

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            Y++  GN   +F ++  +G +S+V+ L+ E+V  + L + A D G P RS T  L I + 
Sbjct: 1544 YSLRAGNGDGRFHLNPSTGALSVVRALNREEVVQHNLTVVAADHGFPRRSATQLLSILVL 1603

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            DVND AP F    ++  V EN+P G  +++V A D D G N ++T       Y G    P
Sbjct: 1604 DVNDEAPTFEKPEYEAHVMENLPAGSPVLQVLATDRDLGANGQVT-------YGGLSGGP 1656

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
             +I P++G + T+  LDRE Q ++ L+V A DGG PP  + AT                 
Sbjct: 1657 FSIHPQTGLIVTTHPLDREEQEQHVLMVYAQDGGLPPNLSKATVRITVGDENDHTPQLES 1716

Query: 369  GQYEVELAEDEPPGTPVVTLTAT--DADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
                VE+ E++     + TL AT  D DE+ RL Y +  G+    F +   +  G+++ A
Sbjct: 1717 ESCSVEVPENQ-SRVALYTLRATDPDGDENGRLEYRVADGDPEQDFILDPVS--GVLSTA 1773

Query: 427  QPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
            + LD +Q   Y LTV   D G   RS T  V + + D N+ AP F  A Y   V ED P+
Sbjct: 1774 RALDREQVAFYSLTVVVQDHGTPPRSATMTVNVRVLDLNDNAPGFAQASYVVEVPEDLPV 1833

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            G+ VL + A D D G N Q+TY L     NE++      F I PQ+G I + + LDRE  
Sbjct: 1834 GSLVLQLEAEDPDEGTNGQVTYYL----GNESLG----MFQIEPQSGRIRSAQELDRERQ 1885

Query: 545  SGYLLTVTARDGGV-PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
              Y     A D       S    V ++V DVND+ P F     T ++     +   V+ +
Sbjct: 1886 PSYSFLAKAVDSAPWEPKSAAVRVTVTVQDVNDHAPAFLHSPVTVSLSRHTPLKQVVATM 1945

Query: 604  GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
             A D D G N  I Y L   +    +F I+  +G I+  + L   S     L  +A D G
Sbjct: 1946 RAEDRDAGANASILYRLATPN---SAFSINSYTGDIQLLQPLSSLSQRQRTLFILATDLG 2002

Query: 664  TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
             P  SST +V I +++       F        + EN+  GT +  I+A     G +  + 
Sbjct: 2003 QPALSSTGVVVIHVQEEPYRGLRFPRSTSEVVLPENAAPGTAVTSIQAVHMG-GSSGRIT 2061

Query: 724  YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEIL 783
            YSI  G++ N+F ++   G+   +  + +D +  SPR +  LV++A +   +  + + + 
Sbjct: 2062 YSIISGNEKNAFLIQPSSGAISVQDSSSLDFE-ASPRLR--LVVQAETTASFGFMAINLN 2118

Query: 784  VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANL-ILL 842
            + DVNDN P    FQ+   NY     V       +YD+ V   L   +  G N  +   +
Sbjct: 2119 LQDVNDNLP---RFQL--QNY-----VAFIWESQSYDSPVIQVLADDLDQGMNGQVTYAI 2168

Query: 843  NET---TGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVR 899
            N++   TG   + PQ  T +   A ++  +      +   M      +     L  + + 
Sbjct: 2169 NQSLPMTGLYHIDPQTGT-ITTAAILDREIWSQTRLVVTAMDRGTPPLVGSATLTVVVMD 2227

Query: 900  LND 902
            +ND
Sbjct: 2228 IND 2230



 Score =  311 bits (763), Expect = 2e-82
 Identities = 254/806 (31%), Positives = 374/806 (46%), Gaps = 54/806 (6%)

Query: 92  IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151
           ID   G + T   LDRE    Y+ +    +           T  +++ + D ND+ P F 
Sbjct: 70  IDENRGIIKTARVLDRETRDHYSFIAVTPE---------GITVEVNIQVNDINDHAPAFP 120

Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG---- 207
           ++  T  + E   V     +    A DAD G  +   Y I G N    F +++  G    
Sbjct: 121 KQHSTFQIPEHTPVGSRFPLDP--AFDADSGLLNTQGYVIKGDNVGQAFRLETRRGPNGV 178

Query: 208 ---DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
              D+ +   LD E   SY LV+ A DGG+P RS+   L ++I+D+NDNAP F  S +  
Sbjct: 179 LYLDLVVSNVLDRENRSSYSLVLEAYDGGTPPRSSQMTLDVSIQDINDNAPAFNQSRYHT 238

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
            +SEN+  G SI++V A DADEG N ++ Y +  +    + D   TID R+G +  +  L
Sbjct: 239 LISENLKPGSSILQVFASDADEGDNGDVIYEINRRQ--SDPDQYFTIDSRTGVIKLNKGL 296

Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX----XXXXXFMPGQYEVELAEDEP 380
           D E +  ++L+V A D    P   TA                   F+      +++E   
Sbjct: 297 DYEVRKVHELVVQARDRAVHPEVTTAFVTIHVRDYNDNQPTMTIIFLSEDGSPQISEGAQ 356

Query: 381 PGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ-NGRGLITVAQPLDFKQERRYVL 439
           PG  V  ++ +D D     +  +T     G+F++T++ N   LI V Q LD ++   Y L
Sbjct: 357 PGQYVARISVSDPDYGEYSNVNVTLEGGDGKFALTTKDNIIYLICVDQLLDREERDSYDL 416

Query: 440 TVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496
            V+ATDSG    R+++  V + + D N+  P+F+   Y  S+ E    G+ VL V+A D 
Sbjct: 417 RVTATDSGTPPLRAESTFV-LQVIDINDNPPLFDQQEYKQSIPEVVYPGSFVLQVTARDK 475

Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556
           D G N ++ YS+    S++    H   F I+P TG ITT   LD E      LTV A D 
Sbjct: 476 DQGPNGEVQYSIVH--SHDT---HSSWFAIDPATGIITTAAPLDYEKDPQPQLTVLATDR 530

Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616
           G P+LS +  V +++ DVNDNEPVF+   Y  ++ E+  VGT   QV ATDAD GL G +
Sbjct: 531 GTPALSSSAVVLVALQDVNDNEPVFRSNFYNVSLKENTPVGTCFLQVTATDADSGLFGSL 590

Query: 617 HYELDP--KDREEGSFVIDPASGVIRTNKALDR-ESVATHDLKAVAIDGGTPPQSSTVIV 673
            Y L           F ID  +G + T + LDR E  + +D    A+DGG    +S V V
Sbjct: 591 SYSLGSGIGSVVPTQFSIDKHTGHLCTTQPLDRDEGTSAYDFTITAVDGG--GLNSMVYV 648

Query: 674 HIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN 733
            + +EDIND+ PVF        IS  S  GT +  + AHD DEG +  V Y I  G+   
Sbjct: 649 KVFLEDINDNRPVFYPLDYAASISTQSMPGTAVLRVTAHDKDEGMHGKVTYRIVLGNSPP 708

Query: 734 SFSLETRQGSDKAELVTMVDLDYESPRKK---YELVIRA---ASPPLWNDVRVEILVTDV 787
            FSL    G        ++ L +    K     +LVI A          + RV I V + 
Sbjct: 709 LFSLNKDTG--------VISLSWSLSGKANTLVQLVISAEDGGGLQAQPNARVNISVVEG 760

Query: 788 NDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD-ADVTDKLQYRILSGNNANLILLNETT 846
             + PV +  Q  F   +D       G V A +    TD + Y I SG+      ++  T
Sbjct: 761 TVSPPVFEQAQYFFTVPEDMLQGASVGAVRAQNPPGHTDDIFYSISSGDPHGYFSIDSDT 820

Query: 847 GSMTLSPQLNTNVPKLATMEVSVTDG 872
           G +  S  L+     +  ++V    G
Sbjct: 821 GQLHTSLPLDHESQAVLILDVQARSG 846



 Score =  310 bits (762), Expect = 3e-82
 Identities = 257/860 (29%), Positives = 393/860 (45%), Gaps = 69/860 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I VLD ND +P FE  +YEA V E   +G+ VL + ATD+D+G N +V       T   L
Sbjct: 1600 ILVLDVNDEAPTFEKPEYEAHVMENLPAGSPVLQVLATDRDLGANGQV-------TYGGL 1652

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +                  F I  ++G ++T   LDRE+  ++ ++V A D   P +   
Sbjct: 1653 SGGP---------------FSIHPQTGLIVTTHPLDREEQEQHVLMVYAQDGGLPPN--- 1694

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             S AT+ + + D+ND+ PQ   ++ +V V E+ S      +  ++ATD D   N  + Y 
Sbjct: 1695 LSKATVRITVGDENDHTPQLESESCSVEVPENQS---RVALYTLRATDPDGDENGRLEYR 1751

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            +  G+ +  F +D +SG +S  + LD EQV  Y L +  QD G+P RS T  + + + D+
Sbjct: 1752 VADGDPEQDFILDPVSGVLSTARALDREQVAFYSLTVVVQDHGTPPRSATMTVNVRVLDL 1811

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI- 309
            NDNAP F  + +   V E++P+G  +++++A D DEG N ++TY      Y GN  L + 
Sbjct: 1812 NDNAPGFAQASYVVEVPEDLPVGSLVLQLEAEDPDEGTNGQVTY------YLGNESLGMF 1865

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD-PPRSATATXXXXXXXXXXXXXXFMP 368
             I+P+SG + ++ +LDRE Q  Y  L  A D     P+SA                 F+ 
Sbjct: 1866 QIEPQSGRIRSAQELDRERQPSYSFLAKAVDSAPWEPKSAAVRVTVTVQDVNDHAPAFLH 1925

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
                V L+   P    V T+ A D D                 FSI S  G   I + QP
Sbjct: 1926 SPVTVSLSRHTPLKQVVATMRAEDRDAGANASILYRLATPNSAFSINSYTGD--IQLLQP 1983

Query: 429  LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
            L    +R+  L + ATD G    S T +V I++ +       F  +     + E+A  GT
Sbjct: 1984 LSSLSQRQRTLFILATDLGQPALSSTGVVVIHVQEEPYRGLRFPRSTSEVVLPENAAPGT 2043

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT--NKLLDRETM 544
             V  + A     G + +ITYS+ S   NE  A     F+I P +GAI+   +  LD E  
Sbjct: 2044 AVTSIQAVHMG-GSSGRITYSIIS--GNEKNA-----FLIQPSSGAISVQDSSSLDFEAS 2095

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
                L V A      +      + +++ DVNDN P F+ Q Y A I E     + V QV 
Sbjct: 2096 PRLRLVVQAE---TTASFGFMAINLNLQDVNDNLPRFQLQNYVAFIWESQSYDSPVIQVL 2152

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            A D D G+NG++ Y ++      G + IDP +G I T   LDRE  +   L   A+D GT
Sbjct: 2153 ADDLDQGMNGQVTYAINQSLPMTGLYHIDPQTGTITTAAILDREIWSQTRLVVTAMDRGT 2212

Query: 665  PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
            PP   +  + + + DIND+ P          + EN  +GT I ++  +D D GP A+ + 
Sbjct: 2213 PPLVGSATLTVVVMDINDNSPTIPFP-WEVRVPENMLLGTQIAQLTGNDVDSGP-ALSYT 2270

Query: 725  SIKGGD-----DSNSFSLETRQGSD-------KAELVTMVDLDYESPRKKYELVIRAASP 772
             +  GD     +  +      +G D         EL + +  DYE   K ++L++RA   
Sbjct: 2271 LVLDGDAYAVLEQPAGGPGVAEGRDAFAINSSSGELRSRLTFDYER-AKAFQLLVRATDA 2329

Query: 773  PLWN-DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRI 831
               +  V V +LVT  ++  P+       F   +        GRV A D D         
Sbjct: 2330 GNASATVTVRVLVTGEDEYDPIFLSPSFSFEVPEGAHKGQSIGRVLATDEDEGADGVVLY 2389

Query: 832  LSGNNANLILLNETTGSMTL 851
                 +    +N+TTG++ L
Sbjct: 2390 SLAKPSPYFAINQTTGTIYL 2409



 Score =  304 bits (746), Expect = 2e-80
 Identities = 253/875 (28%), Positives = 400/875 (45%), Gaps = 53/875 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +++ D ND++P F   +Y   + E    G+++L + A+D D G N +V Y I    +D  
Sbjct: 219  VSIQDINDNAPAFNQSRYHTLISENLKPGSSILQVFASDADEGDNGDVIYEINRRQSD-- 276

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             P+                F ID R+G +     LD E    + ++V+A D+A  V   +
Sbjct: 277  -PDQ--------------YFTIDSRTGVIKLNKGLDYEVRKVHELVVQARDRA--VHPEV 319

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP--VIAKIKATDADVGANSAIR 188
             +TA + +++ D NDN P  +    +      IS    P   +A+I  +D D G  S + 
Sbjct: 320  -TTAFVTIHVRDYNDNQPTMTIIFLSEDGSPQISEGAQPGQYVARISVSDPDYGEYSNVN 378

Query: 189  YAIIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
              + GG+ +   +  D++   + + + LD E+  SY L + A D G+P     +  ++ +
Sbjct: 379  VTLEGGDGKFALTTKDNIIYLICVDQLLDREERDSYDLRVTATDSGTPPLRAESTFVLQV 438

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
             D+NDN P F    +++S+ E V  G  +++V A D D+G N E+ Y++     T +   
Sbjct: 439  IDINDNPPLFDQQEYKQSIPEVVYPGSFVLQVTARDKDQGPNGEVQYSIVHSHDTHS--S 496

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
               IDP +G + T+  LD E   + QL V ATD G P  S++A               F 
Sbjct: 497  WFAIDPATGIITTAAPLDYEKDPQPQLTVLATDRGTPALSSSAVVLVALQDVNDNEPVFR 556

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEI---TGGNTRGRFSITSQNGRGL 422
               Y V L E+ P GT  + +TATDAD      L Y +    G     +FSI    G   
Sbjct: 557  SNFYNVSLKENTPVGTCFLQVTATDADSGLFGSLSYSLGSGIGSVVPTQFSIDKHTGH-- 614

Query: 423  ITVAQPLDFKQ-ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
            +   QPLD  +    Y  T++A D GG +    V++ + D N+  PVF    Y AS+   
Sbjct: 615  LCTTQPLDRDEGTSAYDFTITAVDGGGLNSMVYVKVFLEDINDNRPVFYPLDYAASISTQ 674

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
            +  GT VL V+A D D G++ ++TY +        + +    F +N  TG I+ +  L  
Sbjct: 675  SMPGTAVLRVTAHDKDEGMHGKVTYRI-------VLGNSPPLFSLNKDTGVISLSWSLSG 727

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
            +  +   L ++A DGG         V ISVV+   + PVF+Q  Y   + ED L G SV 
Sbjct: 728  KANTLVQLVISAEDGGGLQAQPNARVNISVVEGTVSPPVFEQAQYFFTVPEDMLQGASVG 787

Query: 602  QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
             V A +   G    I Y +   D   G F ID  +G + T+  LD ES A   L  V   
Sbjct: 788  AVRAQNPP-GHTDDIFYSISSGD-PHGYFSIDSDTGQLHTSLPLDHESQAVLILD-VQAR 844

Query: 662  GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
             G+PP  S   V I + D+ND+ P F S   +  + E +  GTT+  ++A D D G N  
Sbjct: 845  SGSPPAYSNTRVKISVSDVNDNAPTFPSPSDSILLPEATEPGTTVYTLQAEDRDNGANGQ 904

Query: 722  VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPRKKYELVIR-AASPPLWNDVR 779
            V++ +  G D  +FS+E   G+    LV +  L YE S   +  +V R +  P L +   
Sbjct: 905  VNFELVSGGD-GTFSVERSSGA--VRLVGV--LQYEASAAYRLSIVARDSGVPQLSSTFT 959

Query: 780  VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADVTD-KLQYRILSGNNA 837
            + + V   +DN P+  D        ++  PV   F +V A   D  D  L Y + +  +A
Sbjct: 960  LLVHVQAEHDNGPIF-DTLTYRVEVREGVPVSTRFLQVRALARDAEDVTLTYHLRADGDA 1018

Query: 838  NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
                +   +G + +   L+     L  + V  + G
Sbjct: 1019 ASFGIMSESGWLYVKSALDRETRDLYVLTVLASAG 1053



 Score =  284 bits (696), Expect = 3e-74
 Identities = 245/893 (27%), Positives = 397/893 (44%), Gaps = 66/893 (7%)

Query: 15   DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
            D ND+ PVF    Y  S++E    GT  L + ATD D G    + Y++            
Sbjct: 547  DVNDNEPVFRSNFYNVSLKENTPVGTCFLQVTATDADSGLFGSLSYSL------------ 594

Query: 75   AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREK-VARYTVLVKATDQASPVSDRLSST 133
                       V   F ID  +G L T   LDR++  + Y   + A D        L+S 
Sbjct: 595  ----GSGIGSVVPTQFSIDKHTGHLCTTQPLDRDEGTSAYDFTITAVDGGG-----LNSM 645

Query: 134  ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG 193
              + V + D NDN P F    Y  S+    S+    V+ ++ A D D G +  + Y I+ 
Sbjct: 646  VYVKVFLEDINDNRPVFYPLDYAASISTQ-SMPGTAVL-RVTAHDKDEGMHGKVTYRIVL 703

Query: 194  GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDN 253
            GN+   FS++  +G +SL  +L  +     +LVI A+DGG        ++ I++ +   +
Sbjct: 704  GNSPPLFSLNKDTGVISLSWSLSGKANTLVQLVISAEDGGGLQAQPNARVNISVVEGTVS 763

Query: 254  APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313
             P F  + +  +V E++  G S+  V+A +   G   ++ Y+++  D  G      +ID 
Sbjct: 764  PPVFEQAQYFFTVPEDMLQGASVGAVRAQN-PPGHTDDIFYSISSGDPHGY----FSIDS 818

Query: 314  RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373
             +G ++TS  LD E+QA   L V A  G  P  S T                  P    +
Sbjct: 819  DTGQLHTSLPLDHESQAVLILDVQARSGSPPAYSNTRVKISVSDVNDNAPTFPSPSD-SI 877

Query: 374  ELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431
             L E   PGT V TL A D D   + ++++E+  G   G FS+  +   G + +   L +
Sbjct: 878  LLPEATEPGTTVYTLQAEDRDNGANGQVNFELVSGGD-GTFSV--ERSSGAVRLVGVLQY 934

Query: 432  KQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
            +    Y L++ A DSG    S T  + +++   ++  P+F+   Y   V E  P+ T  L
Sbjct: 935  EASAAYRLSIVARDSGVPQLSSTFTLLVHVQAEHDNGPIFDTLTYRVEVREGVPVSTRFL 994

Query: 490  VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
             V A   D   +  +TY L ++   +A +     F I  ++G +     LDRET   Y+L
Sbjct: 995  QVRALARDAE-DVTLTYHLRAD--GDAAS-----FGIMSESGWLYVKSALDRETRDLYVL 1046

Query: 550  TVTARDGGVPS-----LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
            TV A  GG  S      + T+ V IS+ D NDN P   ++ Y   + E+   G+SV +V 
Sbjct: 1047 TVLASAGGSGSGGEARKTGTSTVRISITDENDNSPRLSEERYFFTVPENQAPGSSVGRVM 1106

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            A+D D G N R+ Y L   D    +F+I   +G + T  +LDRE  +++ L  +  DGG 
Sbjct: 1107 ASDRDAGQNSRLTYRLLQHD---SNFLIHTQTGELSTKHSLDRELQSSYQLLVIVQDGGA 1163

Query: 665  PPQSSTVIVHIKIEDINDSPPVF----ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
            PP+S+T  +++ + D ND+ PVF        L   + E  P G  +  ++A DPDEG N 
Sbjct: 1164 PPRSATGTIYVTVLDENDNAPVFLHITGGQELPVQVLEEKPSGLLVASLQAKDPDEGENG 1223

Query: 721  VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWND 777
             + YS+ G   +  F+L T  G    EL T   L   + R +Y   + A+     P    
Sbjct: 1224 TITYSLTGA-WAERFTLHTATG----ELRTATVL-RRADRAEYVFTVTASDRGMVPCTTS 1277

Query: 778  VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNA 837
              V I V   +   P      +     +   P    G V   DA    +L Y ++ G   
Sbjct: 1278 AIVRIQVLPSSRLLPRPDATVLTLQPLEGVRPGSVIGSVAPPDAPARGQLTYTVIGGGGD 1337

Query: 838  NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEE 890
               +++  TG +  + +L+       T++VS  D  +   +   + V+++ ++
Sbjct: 1338 GTFVVDSVTGEIYAARELDYEARARHTLQVSAEDTQHGYPSSRLVLVQILVQD 1390



 Score =  274 bits (671), Expect = 3e-71
 Identities = 235/806 (29%), Positives = 368/806 (45%), Gaps = 67/806 (8%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            ++ ++ + D ND+ PVF    Y AS+   +  GT VL + A D+D G + +V Y I L  
Sbjct: 646  VYVKVFLEDINDNRPVFYPLDYAASISTQSMPGTAVLRVTAHDKDEGMHGKVTYRIVLGN 705

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
            +  L                   F ++  +G +    SL  +      +++ A D     
Sbjct: 706  SPPL-------------------FSLNKDTGVISLSWSLSGKANTLVQLVISAEDGGGL- 745

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
              +    A +++++++   + P F +  Y  +V ED+       +  ++A +   G    
Sbjct: 746  --QAQPNARVNISVVEGTVSPPVFEQAQYFFTVPEDM--LQGASVGAVRAQNPP-GHTDD 800

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            I Y+I  G+    FSIDS +G +     LD+E      L ++A+ G  P+ SNT ++ I+
Sbjct: 801  IFYSISSGDPHGYFSIDSDTGQLHTSLPLDHESQAVLILDVQARSGSPPAYSNT-RVKIS 859

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            + DVNDNAP F +      + E    G ++  +QA D D G N ++ + +     +G  D
Sbjct: 860  VSDVNDNAPTFPSPSDSILLPEATEPGTTVYTLQAEDRDNGANGQVNFELV----SGG-D 914

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
               +++  SG V   G L  E  A Y+L + A D G P  S+T T              F
Sbjct: 915  GTFSVERSSGAVRLVGVLQYEASAAYRLSIVARDSGVPQLSSTFTLLVHVQAEHDNGPIF 974

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDAD-EDNRLHYEITGGNTRGRFSITSQNGRGLITV 425
                Y VE+ E  P  T  + + A   D ED  L Y +        F I S++G   + V
Sbjct: 975  DTLTYRVEVREGVPVSTRFLQVRALARDAEDVTLTYHLRADGDAASFGIMSESG--WLYV 1032

Query: 426  AQPLDFKQERRYVLTVSAT----DSGG---RSDTAMVQINITDANNYAPVFENAPYTASV 478
               LD +    YVLTV A+     SGG   ++ T+ V+I+ITD N+ +P      Y  +V
Sbjct: 1033 KSALDRETRDLYVLTVLASAGGSGSGGEARKTGTSTVRISITDENDNSPRLSEERYFFTV 1092

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             E+   G++V  V A+D D G N+++TY L           HD  F+I+ QTG ++T   
Sbjct: 1093 PENQAPGSSVGRVMASDRDAGQNSRLTYRL---------LQHDSNFLIHTQTGELSTKHS 1143

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ----QLYTANIMEDA 594
            LDRE  S Y L V  +DGG P  S T  + ++V+D NDN PVF      Q     ++E+ 
Sbjct: 1144 LDRELQSSYQLLVIVQDGGAPPRSATGTIYVTVLDENDNAPVFLHITGGQELPVQVLEEK 1203

Query: 595  LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654
              G  V+ + A D D G NG I Y L     E   F +  A+G +RT   L R   A + 
Sbjct: 1204 PSGLLVASLQAKDPDEGENGTITYSLTGAWAER--FTLHTATGELRTATVLRRADRAEYV 1261

Query: 655  LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
                A D G  P +++ IV I++   +   P  ++  LT    E    G+ IG +    P
Sbjct: 1262 FTVTASDRGMVPCTTSAIVRIQVLPSSRLLPRPDATVLTLQPLEGVRPGSVIGSVA--PP 1319

Query: 715  DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP-- 772
            D      + Y++ GG    +F +++  G    E+    +LDYE+ R ++ L + A     
Sbjct: 1320 DAPARGQLTYTVIGGGGDGTFVVDSVTG----EIYAARELDYEA-RARHTLQVSAEDTQH 1374

Query: 773  --PLWNDVRVEILVTDVNDNAPVMKD 796
              P    V V+ILV D ND AP   +
Sbjct: 1375 GYPSSRLVLVQILVQDCNDQAPTFPE 1400



 Score =  269 bits (660), Expect = 6e-70
 Identities = 248/872 (28%), Positives = 396/872 (45%), Gaps = 81/872 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I+V++     PVFE  QY  +V E    G +V  ++A +   G   ++ Y+I   + D  
Sbjct: 755  ISVVEGTVSPPVFEQAQYFFTVPEDMLQGASVGAVRAQNPP-GHTDDIFYSIS--SGDP- 810

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F ID  +G L T   LD E  A   + V+A   + P     
Sbjct: 811  ----------------HGYFSIDSDTGQLHTSLPLDHESQAVLILDVQARSGSPPAY--- 851

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             S   + +++ D NDN P F   + ++ + E  +      +  ++A D D GAN  + + 
Sbjct: 852  -SNTRVKISVSDVNDNAPTFPSPSDSILLPE--ATEPGTTVYTLQAEDRDNGANGQVNFE 908

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            ++ G     FS++  SG V LV  L YE   +YRL I A+D G P  S+T  LL++++  
Sbjct: 909  LVSGGDGT-FSVERSSGAVRLVGVLQYEASAAYRLSIVARDSGVPQLSSTFTLLVHVQAE 967

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM-TDKDYTGNVDLPI 309
            +DN P F T  ++  V E VP+    ++V+A  A +  +  LTY +  D D         
Sbjct: 968  HDNGPIFDTLTYRVEVREGVPVSTRFLQVRAL-ARDAEDVTLTYHLRADGDAAS-----F 1021

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTAT-----DGGDPPRSATATXXXXXXXXXXXXX 364
             I   SGW+Y    LDRET+  Y L V A+      GG+  ++ T+T             
Sbjct: 1022 GIMSESGWLYVKSALDRETRDLYVLTVLASAGGSGSGGEARKTGTSTVRISITDENDNSP 1081

Query: 365  XFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGL 422
                 +Y   + E++ PG+ V  + A+D D  +++RL Y +   ++   F I +Q G   
Sbjct: 1082 RLSEERYFFTVPENQAPGSSVGRVMASDRDAGQNSRLTYRLLQHDSN--FLIHTQTGE-- 1137

Query: 423  ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAP----YTA 476
            ++    LD + +  Y L V   D G   RS T  + + + D N+ APVF +         
Sbjct: 1138 LSTKHSLDRELQSSYQLLVIVQDGGAPPRSATGTIYVTVLDENDNAPVFLHITGGQELPV 1197

Query: 477  SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
             V E+ P G  V  + A D D G N  ITYSL+   +        ++F ++  TG + T 
Sbjct: 1198 QVLEEKPSGLLVASLQAKDPDEGENGTITYSLTGAWA--------ERFTLHTATGELRTA 1249

Query: 537  KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
             +L R   + Y+ TVTA D G+   + +  V I V+  +   P     + T   +E    
Sbjct: 1250 TVLRRADRAEYVFTVTASDRGMVPCTTSAIVRIQVLPSSRLLPRPDATVLTLQPLEGVRP 1309

Query: 597  GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
            G+ +  V   DA     G++ Y +     + G+FV+D  +G I   + LD E+ A H L+
Sbjct: 1310 GSVIGSVAPPDAPA--RGQLTYTVIGGGGD-GTFVVDSVTGEIYAARELDYEARARHTLQ 1366

Query: 657  AVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
              A D     P S  V+V I ++D ND  P F  D +T  + EN+  G+++   +A D D
Sbjct: 1367 VSAEDTQHGYPSSRLVLVQILVQDCNDQAPTFPEDPITIVVPENAQAGSSVFTFQALDGD 1426

Query: 716  -EGPNAVVHYSIKGGDDSNS-FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---- 769
              GPN+ V Y++   +   + F L++R G     L     LD E+    + LV+ A    
Sbjct: 1427 GVGPNSQVRYALLRQEPPGAPFHLDSRSGL----LSLHQSLDREAV-ASFLLVVEATDQA 1481

Query: 770  --ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVTD- 825
               S    + V   + VTDVNDNAPV      +  +  +  P G     V A D D+ + 
Sbjct: 1482 RNVSQRRSSAVTARVFVTDVNDNAPVFLSPAAV--SVTEDRPTGFVALHVVAQDNDLGEN 1539

Query: 826  -KLQYRILSGNNANLILLNETTGSMTLSPQLN 856
             ++ Y + +GN      LN +TG++++   LN
Sbjct: 1540 GRVSYSLRAGNGDGRFHLNPSTGALSVVRALN 1571



 Score =  196 bits (479), Expect = 5e-48
 Identities = 173/589 (29%), Positives = 264/589 (44%), Gaps = 39/589 (6%)

Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325
           + E  P G  I  + A     G +A + Y ++ ++ +G V   + ID   G + T+  LD
Sbjct: 28  IDEEQPAGTIIGDISA-GLPPGTSAYM-YFISAQEGSG-VTTDLWIDENRGIIKTARVLD 84

Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
           RET+  Y  +         P   T                F       ++ E  P G+  
Sbjct: 85  RETRDHYSFIAVT------PEGITVEVNIQVNDINDHAPAFPKQHSTFQIPEHTPVGSRF 138

Query: 386 VTLTATDADED--NRLHYEITGGNTRGRFSITSQNG-RGL----ITVAQPLDFKQERRYV 438
               A DAD    N   Y I G N    F + ++ G  G+    + V+  LD +    Y 
Sbjct: 139 PLDPAFDADSGLLNTQGYVIKGDNVGQAFRLETRRGPNGVLYLDLVVSNVLDRENRSSYS 198

Query: 439 LTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496
           L + A D G   RS    + ++I D N+ AP F  + Y   + E+   G+++L V A+D+
Sbjct: 199 LVLEAYDGGTPPRSSQMTLDVSIQDINDNAPAFNQSRYHTLISENLKPGSSILQVFASDA 258

Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556
           D G N  + Y +     N   +  DQ F I+ +TG I  NK LD E    + L V ARD 
Sbjct: 259 DEGDNGDVIYEI-----NRRQSDPDQYFTIDSRTGVIKLNKGLDYEVRKVHELVVQARDR 313

Query: 557 GVPSLSDTTDVEISVVDVNDNEP----VFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612
            V     T  V I V D NDN+P    +F  +  +  I E A  G  V+++  +D D G 
Sbjct: 314 AVHPEVTTAFVTIHVRDYNDNQPTMTIIFLSEDGSPQISEGAQPGQYVARISVSDPDYGE 373

Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672
              ++  L+  D +      D    +I  ++ LDRE   ++DL+  A D GTPP  +   
Sbjct: 374 YSNVNVTLEGGDGKFALTTKDNIIYLICVDQLLDREERDSYDLRVTATDSGTPPLRAEST 433

Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732
             +++ DIND+PP+F+       I E    G+ + ++ A D D+GPN  V YSI    D+
Sbjct: 434 FVLQVIDINDNPPLFDQQEYKQSIPEVVYPGSFVLQVTARDKDQGPNGEVQYSIVHSHDT 493

Query: 733 NS--FSLETRQGSDKAELVTMVDLDYE-SPRKKYE-LVIRAASPPLWNDVRVEILVTDVN 788
           +S  F+++   G     + T   LDYE  P+ +   L     +P L +   V + + DVN
Sbjct: 494 HSSWFAIDPATGI----ITTAAPLDYEKDPQPQLTVLATDRGTPALSSSAVVLVALQDVN 549

Query: 789 DNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDAD--VTDKLQYRILSG 834
           DN PV +       + K+  PVG  F +V A DAD  +   L Y + SG
Sbjct: 550 DNEPVFRS-NFYNVSLKENTPVGTCFLQVTATDADSGLFGSLSYSLGSG 597



 Score = 41.9 bits (94), Expect = 0.25
 Identities = 48/158 (30%), Positives = 68/158 (43%), Gaps = 14/158 (8%)

Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY--SIKGGDDSNSFSLETRQGSDKAELV 749
           L   I E  P GT IG+I A  P  G +A +++  + +G   +    ++  +G  K   V
Sbjct: 24  LDLQIDEEQPAGTIIGDISAGLP-PGTSAYMYFISAQEGSGVTTDLWIDENRGIIKTARV 82

Query: 750 TMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809
               LD E+ R  Y  +   A  P    V V I V D+ND+AP        F    +  P
Sbjct: 83  ----LDRET-RDHYSFI---AVTPEGITVEVNIQVNDINDHAPAFPKQHSTF-QIPEHTP 133

Query: 810 VGP-FGRVPAYDADV-TDKLQYRILSGNNANLILLNET 845
           VG  F   PA+DAD      Q  ++ G+N       ET
Sbjct: 134 VGSRFPLDPAFDADSGLLNTQGYVIKGDNVGQAFRLET 171


>UniRef50_Q4S3T6 Cluster: Chromosome 20 SCAF14744, whole genome
            shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
            Chromosome 20 SCAF14744, whole genome shotgun sequence -
            Tetraodon nigroviridis (Green puffer)
          Length = 2289

 Score =  340 bits (835), Expect = 4e-91
 Identities = 268/892 (30%), Positives = 428/892 (47%), Gaps = 73/892 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I + D ND+ PVFE   ++A + E  S    VL + A D D G N ++EY+I     D 
Sbjct: 329  EITIQDVNDNYPVFEKDPFQADILENLSP-QRVLVVSAVDLDSGPNGQLEYSI----VDG 383

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             N E++              F I+  +G + T   LDREKVA+Y++ VKATD   P   +
Sbjct: 384  -NKENS--------------FSINRATGEIRTTRPLDREKVAQYSLKVKATDWGLP---Q 425

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG--ANSAI 187
             +    + +NI+D NDN P+FS K ++ +V E+  V     + ++  TD D G  AN   
Sbjct: 426  KNMAVKVLINILDVNDNAPRFS-KIFSATVAENAPV--GYTVTRVTTTDEDAGSNANECQ 482

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
             +  I     ++F  +S +G ++         +  +  ++ A D       + T +++NI
Sbjct: 483  HWGDI-CKQPLKFQ-NSTAGSLN---------INRHSFIVTASDRAVQPLMSETTVIVNI 531

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYD-ADEGVNAELTYTMTDKDYTGNVD 306
             D NDN P+F +  +   V+++V +G  + RV A+D  D G+N+E+ Y +T     GN  
Sbjct: 532  VDSNDNPPQFESPNYFTPVAKSVKVGTRLTRVVAHDKKDFGLNSEVEYVITG----GNSS 587

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
                +D  SGW+  +  L  +    + + +TATD G+PP S   +              F
Sbjct: 588  SKFQLDKSSGWITVASSLISDVNKIFMVGITATDRGNPPLSGLTSLRIAVTEENHHTPEF 647

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLIT 424
               Q    + E    GT + TL+A D D+D    + Y IT GN RG FSI S++  G+++
Sbjct: 648  SQSQVSATIPESLAVGTAIRTLSARDKDKDMNGVITYNITSGNDRGLFSINSRS--GVLS 705

Query: 425  VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ--INITDANNYAPVFENAPYTASVFEDA 482
            +A PLDF++++++ L VSA D G  + T+ V   +++TD N+  PVFE   Y   V E+ 
Sbjct: 706  LAGPLDFEEKQQHNLRVSAIDGGWIAKTSYVSVTVHVTDVNDNPPVFEPDEYFPVVQENV 765

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
            P GTTV+ ++A D D G NA + Y + S  S+         FVI+P TG ITT   LD E
Sbjct: 766  PSGTTVVKMNAKDGDSGANAVMAYVIQSSDSD--------LFVIDPNTGTITTQGFLDYE 817

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
                Y LTV A +          +V I +   N+  P F  + Y   + E A  GT V +
Sbjct: 818  AKQVYHLTVKAFNVPDEERCSLANVNIQLKGANEYVPRFVSKQYYFEVSEAAPKGTVVGE 877

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
            V A+D D G NG ++Y +  K R++G F I+  +G I    ALDRE      LK +A + 
Sbjct: 878  VFASDRDQGDNGVVYYLIFGKSRKKG-FGINETTGQIYVTGALDREKEEKISLKVLAKNA 936

Query: 663  GT--PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN- 719
            G+        V V+I + D ND PPVF  +     +SE    G  +  + A D D  P+ 
Sbjct: 937  GSIRGADIDEVFVNITVLDAND-PPVFTQELYDVQVSEGLSPGGLVTFVSAEDSDSVPSW 995

Query: 720  AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR 779
            +   YSI    D   F++ T+ G  +  +   +D +         L +   +PP      
Sbjct: 996  SRFSYSIAPESDQKVFTINTKTG--QVSVAAPLDRERTPVYNLTVLAVDTGTPPATGSAT 1053

Query: 780  VEILVTDVNDNAPVM-KDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK---LQYRILSGN 835
            V + + D+NDN P +   +  +  N +    V     + A DAD+        + +LS  
Sbjct: 1054 VIVNLEDINDNGPTLTTSYAEVMENQRAGTAV---TTLTASDADLPPNRGPFLFSLLSSG 1110

Query: 836  NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRL 886
            +AN       +G++T S +++        + V + D GV ++ +   + V++
Sbjct: 1111 SANSYFSLSQSGALTTSREIDREQISDFYLSVVIKDAGVPQMSSTGTIHVKV 1162



 Score =  320 bits (787), Expect = 3e-85
 Identities = 280/1009 (27%), Positives = 450/1009 (44%), Gaps = 70/1009 (6%)

Query: 110  VARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP 169
            + R++ +V A+D+A  V   +S T T+ VNI+D NDN PQF    Y   V + + V    
Sbjct: 504  INRHSFIVTASDRA--VQPLMSET-TVIVNIVDSNDNPPQFESPNYFTPVAKSVKVGTR- 559

Query: 170  VIAKIKATDA-DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIR 228
             + ++ A D  D G NS + Y I GGN+  +F +D  SG +++  +L  +  + + + I 
Sbjct: 560  -LTRVVAHDKKDFGLNSEVEYVITGGNSSSKFQLDKSSGWITVASSLISDVNKIFMVGIT 618

Query: 229  AQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV 288
            A D G+P  S  T L I + + N + P F  S    ++ E++ +G +I  + A D D+ +
Sbjct: 619  ATDRGNPPLSGLTSLRIAVTEENHHTPEFSQSQVSATIPESLAVGTAIRTLSARDKDKDM 678

Query: 289  NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348
            N  +TY +T    +GN     +I+ RSG +  +G LD E + ++ L V+A DGG   +++
Sbjct: 679  NGVITYNIT----SGNDRGLFSINSRSGVLSLAGPLDFEEKQQHNLRVSAIDGGWIAKTS 734

Query: 349  TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGN 407
              +              F P +Y   + E+ P GT VV + A D D   N +   +   +
Sbjct: 735  YVSVTVHVTDVNDNPPVFEPDEYFPVVQENVPSGTTVVKMNAKDGDSGANAVMAYVIQSS 794

Query: 408  TRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA--TDSGGRSDTAMVQINITDANNY 465
                F I      G IT    LD++ ++ Y LTV A       R   A V I +  AN Y
Sbjct: 795  DSDLFVIDPNT--GTITTQGFLDYEAKQVYHLTVKAFNVPDEERCSLANVNIQLKGANEY 852

Query: 466  APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525
             P F +  Y   V E AP GT V  V A+D D G N  + Y +  +   +        F 
Sbjct: 853  VPRFVSKQYYFEVSEAAPKGTVVGEVFASDRDQGDNGVVYYLIFGKSRKKG-------FG 905

Query: 526  INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD--VEISVVDVNDNEPVFKQ 583
            IN  TG I     LDRE      L V A++ G    +D  +  V I+V+D ND  PVF Q
Sbjct: 906  INETTGQIYVTGALDREKEEKISLKVLAKNAGSIRGADIDEVFVNITVLDAND-PPVFTQ 964

Query: 584  QLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642
            +LY   + E    G  V+ V A D+D V    R  Y + P + ++  F I+  +G +   
Sbjct: 965  ELYDVQVSEGLSPGGLVTFVSAEDSDSVPSWSRFSYSIAP-ESDQKVFTINTKTGQVSVA 1023

Query: 643  KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
              LDRE    ++L  +A+D GTPP + +  V + +EDIND+ P   +      + EN   
Sbjct: 1024 APLDRERTPVYNLTVLAVDTGTPPATGSATVIVNLEDINDNGPTLTTSYAE--VMENQRA 1081

Query: 703  GTTIGEIRAHDPDEGPN-AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761
            GT +  + A D D  PN     +S+     +NS+   ++ G+    L T  ++D E    
Sbjct: 1082 GTAVTTLTASDADLPPNRGPFLFSLLSSGSANSYFSLSQSGA----LTTSREIDREQISD 1137

Query: 762  KY-ELVIRAASPPLWNDV-RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY 819
             Y  +VI+ A  P  +    + + V D NDN    +  +I  + + + FP G  G V   
Sbjct: 1138 FYLSVVIKDAGVPQMSSTGTIHVKVNDQNDNPSEPRAVEIFVHYFGNMFPGGLLGDVKPQ 1197

Query: 820  DADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSV--TDGVN-EI 876
            D D+ D+    ++  ++    + +  TG+  L+ +  +      T E+++  +DGV+  +
Sbjct: 1198 DPDIQDRFHCSLIPPSSG---IFSIPTGTCNLNSKARSTD---GTFEITIRSSDGVHGSV 1251

Query: 877  KAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSV 936
             +  ++     T   + NSI +RL     + FL+     ++  L         N  +  +
Sbjct: 1252 SSTARVLFMGFTNATVDNSILIRLQSQGVKSFLT---NHYLSFLRI------ANSKLAGL 1302

Query: 937  QDDTDVTGNILNVSFSARRPD-AEVGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVL 995
                  TG +L  +F           V      + +P+ +       +  L R + VQ+ 
Sbjct: 1303 G-----TGVLLYGAFELNNQTFLMAAVKRSHGQYVNPSGVATFFQSIKDILYRQSGVQID 1357

Query: 996  PFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNC 1055
              D + C H PC N   C   L  G       S  V+     P+  + C C  G+TG  C
Sbjct: 1358 AVDYDPCTHNPCQNGGSCKRRLGVGPDMRSEESVPVILVFSRPLQPYACSCRPGYTGALC 1417

Query: 1056 ETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCE 1104
            ET + +  C+     S C +G  C     GG     C+    +T   CE
Sbjct: 1418 ETDINE--CQ----PSPCHNGGTC-HNLVGGF---SCTCPEGFTGMACE 1456



 Score =  304 bits (747), Expect = 2e-80
 Identities = 226/715 (31%), Positives = 349/715 (48%), Gaps = 53/715 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQ-DIGKNAEVEYTIELVTADT 69
            +N++D ND+ P FE   Y   V +    GT +  + A D+ D G N+EVEY I   T   
Sbjct: 529  VNIVDSNDNPPQFESPNYFTPVAKSVKVGTRLTRVVAHDKKDFGLNSEVEYVI---TGGN 585

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             + +                F++D  SG +   +SL  +    + V + ATD+ +P    
Sbjct: 586  SSSK----------------FQLDKSSGWITVASSLISDVNKIFMVGITATDRGNPP--- 626

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            LS   ++ + + ++N + P+FS+   + ++ E ++V     I  + A D D   N  I Y
Sbjct: 627  LSGLTSLRIAVTEENHHTPEFSQSQVSATIPESLAV--GTAIRTLSARDKDKDMNGVITY 684

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             I  GN +  FSI+S SG +SL   LD+E+ + + L + A DGG  ++++   + +++ D
Sbjct: 685  NITSGNDRGLFSINSRSGVLSLAGPLDFEEKQQHNLRVSAIDGGWIAKTSYVSVTVHVTD 744

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            VNDN P F    +   V ENVP G ++V++ A D D G NA + Y +   D     DL  
Sbjct: 745  VNDNPPVFEPDEYFPVVQENVPSGTTVVKMNAKDGDSGANAVMAYVIQSSD----SDL-F 799

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             IDP +G + T G LD E +  Y L V A +  D  R + A               F+  
Sbjct: 800  VIDPNTGTITTQGFLDYEAKQVYHLTVKAFNVPDEERCSLANVNIQLKGANEYVPRFVSK 859

Query: 370  QYEVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGR-FSITSQNGRGLITVAQ 427
            QY  E++E  P GT V  + A+D D+ DN + Y +  G +R + F I    G+  +T A 
Sbjct: 860  QYYFEVSEAAPKGTVVGEVFASDRDQGDNGVVYYLIFGKSRKKGFGINETTGQIYVTGA- 918

Query: 428  PLDFKQERRYVLTVSATDS----GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
             LD ++E +  L V A ++    G   D   V I + DAN+  PVF    Y   V E   
Sbjct: 919  -LDREKEEKISLKVLAKNAGSIRGADIDEVFVNITVLDAND-PPVFTQELYDVQVSEGLS 976

Query: 484  IGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
             G  V  VSA DSD V   ++ +YS++ E S++ V      F IN +TG ++    LDRE
Sbjct: 977  PGGLVTFVSAEDSDSVPSWSRFSYSIAPE-SDQKV------FTINTKTGQVSVAAPLDRE 1029

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
                Y LTV A D G P  + +  V +++ D+NDN P        A +ME+   GT+V+ 
Sbjct: 1030 RTPVYNLTVLAVDTGTPPATGSATVIVNLEDINDNGPTLTTSY--AEVMENQRAGTAVTT 1087

Query: 603  VGATDADVGLN-GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
            + A+DAD+  N G   + L         F +   SG + T++ +DRE ++   L  V  D
Sbjct: 1088 LTASDADLPPNRGPFLFSLLSSGSANSYFSLS-QSGALTTSREIDREQISDFYLSVVIKD 1146

Query: 662  GGTPPQSSTVIVHIKIEDINDSPPVFES-DCLTFYISENSPIGTTIGEIRAHDPD 715
             G P  SST  +H+K+ D ND+P    + +    Y     P G  +G+++  DPD
Sbjct: 1147 AGVPQMSSTGTIHVKVNDQNDNPSEPRAVEIFVHYFGNMFP-GGLLGDVKPQDPD 1200



 Score =  299 bits (735), Expect = 5e-79
 Identities = 251/867 (28%), Positives = 396/867 (45%), Gaps = 72/867 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + V D ND+ P F    Y   +    ++G+ V  +  TD+D G NA++ Y++        
Sbjct: 127 VTVADINDNPPRFHHHPYVTHIPASTAAGSLVFAVTVTDEDAGSNAQLHYSL-------- 178

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                            + F+ID   GA+     L        TV VK    A+P +D  
Sbjct: 179 ------------IGRSSEKFKIDPIRGAITANEKLTGSSEVTLTVRVK-DGGANPKTDM- 224

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
               T+ V  +    ++P    K    +  E  S   N ++  +  +    G  S   Y 
Sbjct: 225 ---TTVTVRFVTGG-SFPVIKLKERAFTFPE--SQPANHIVTTVTGSSMRGGPLS---YY 275

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
           I  GN    F ID LSG++S+   LDYE ++ Y L I A+D G P  S+  ++ I I+DV
Sbjct: 276 IASGNLDHAFHIDQLSGELSIRHPLDYEHIQKYVLWIEARDQGFPPYSSYEKVEITIQDV 335

Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
           NDN P F    FQ  + EN+     ++ V A D D G N +L Y++ D    GN +   +
Sbjct: 336 NDNYPVFEKDPFQADILENLS-PQRVLVVSAVDLDSGPNGQLEYSIVD----GNKENSFS 390

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
           I+  +G + T+  LDRE  A+Y L V ATD G P ++                  F    
Sbjct: 391 INRATGEIRTTRPLDREKVAQYSLKVKATDWGLPQKNMAVKVLINILDVNDNAPRFSK-I 449

Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
           +   +AE+ P G  V  +T TD D  +  + E        +  +  QN     + A  L+
Sbjct: 450 FSATVAENAPVGYTVTRVTTTDEDAGSNAN-ECQHWGDICKQPLKFQN-----STAGSLN 503

Query: 431 FKQERRYVLTVSATDSGGR---SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
                R+   V+A+D   +   S+T ++ +NI D+N+  P FE+  Y   V +   +GT 
Sbjct: 504 I---NRHSFIVTASDRAVQPLMSETTVI-VNIVDSNDNPPQFESPNYFTPVAKSVKVGTR 559

Query: 488 VLVVSATD-SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
           +  V A D  D G+N+++ Y ++         +   +F ++  +G IT    L  +    
Sbjct: 560 LTRVVAHDKKDFGLNSEVEYVITG-------GNSSSKFQLDKSSGWITVASSLISDVNKI 612

Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
           +++ +TA D G P LS  T + I+V + N + P F Q   +A I E   VGT++  + A 
Sbjct: 613 FMVGITATDRGNPPLSGLTSLRIAVTEENHHTPEFSQSQVSATIPESLAVGTAIRTLSAR 672

Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
           D D  +NG I Y +     + G F I+  SGV+     LD E    H+L+  AIDGG   
Sbjct: 673 DKDKDMNGVITYNI-TSGNDRGLFSINSRSGVLSLAGPLDFEEKQQHNLRVSAIDGGWIA 731

Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
           ++S V V + + D+ND+PPVFE D     + EN P GTT+ ++ A D D G NAV+ Y I
Sbjct: 732 KTSYVSVTVHVTDVNDNPPVFEPDEYFPVVQENVPSGTTVVKMNAKDGDSGANAVMAYVI 791

Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP---LWNDVRVEIL 783
           +   DS+ F ++   G+    + T   LDYE+ ++ Y L ++A + P     +   V I 
Sbjct: 792 Q-SSDSDLFVIDPNTGT----ITTQGFLDYEA-KQVYHLTVKAFNVPDEERCSLANVNIQ 845

Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADVTDK--LQYRILSGNNANLI 840
           +   N+  P     Q  F    +  P G   G V A D D  D   + Y I   +     
Sbjct: 846 LKGANEYVPRFVSKQYYF-EVSEAAPKGTVVGEVFASDRDQGDNGVVYYLIFGKSRKKGF 904

Query: 841 LLNETTGSMTLSPQLNTNVPKLATMEV 867
            +NETTG + ++  L+    +  +++V
Sbjct: 905 GINETTGQIYVTGALDREKEEKISLKV 931



 Score =  292 bits (717), Expect = 8e-77
 Identities = 226/753 (30%), Positives = 348/753 (46%), Gaps = 50/753 (6%)

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           LS T  + V + D NDN P FS  T+  ++ ED + T   V+  + ++DADVG N  I Y
Sbjct: 15  LSGTCMVTVFVSDVNDNAPVFSTSTFHTTITED-APTGTDVLL-VNSSDADVGNNGVISY 72

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR-SNTTQLLINIR 248
           ++ GG+ Q  FSI+  +G +     LD E+  +Y+L++ A DGG P   S++  + + + 
Sbjct: 73  SLSGGHGQ--FSINPATGQIITSSVLDREERANYQLLVVATDGGQPQGLSSSATVSVTVA 130

Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
           D+NDN PRF+   +   +  +   G  +  V   D D G NA+L Y++      G     
Sbjct: 131 DINDNPPRFHHHPYVTHIPASTAAGSLVFAVTVTDEDAGSNAQLHYSL-----IGRSSEK 185

Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
             IDP  G +  + +L   ++    L V   DGG  P++   T               + 
Sbjct: 186 FKIDPIRGAITANEKLTGSSEV--TLTVRVKDGGANPKTDMTTVTVRFVTGGSFPVIKLK 243

Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
            +      E +P    V T+T +       L Y I  GN    F I   +G   +++  P
Sbjct: 244 -ERAFTFPESQPANHIVTTVTGSSM-RGGPLSYYIASGNLDHAFHIDQLSGE--LSIRHP 299

Query: 429 LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
           LD++  ++YVL + A D G    S    V+I I D N+  PVFE  P+ A + E+     
Sbjct: 300 LDYEHIQKYVLWIEARDQGFPPYSSYEKVEITIQDVNDNYPVFEKDPFQADILENLS-PQ 358

Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
            VLVVSA D D G N Q+ YS+          + +  F IN  TG I T + LDRE ++ 
Sbjct: 359 RVLVVSAVDLDSGPNGQLEYSIVD-------GNKENSFSINRATGEIRTTRPLDREKVAQ 411

Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
           Y L V A D G+P  +    V I+++DVNDN P F  ++++A + E+A VG +V++V  T
Sbjct: 412 YSLKVKATDWGLPQKNMAVKVLINILDVNDNAPRF-SKIFSATVAENAPVGYTVTRVTTT 470

Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
           D D G N         + +  G     P      T  +L   ++  H     A D    P
Sbjct: 471 DEDAGSNAN-------ECQHWGDICKQPLKFQNSTAGSL---NINRHSFIVTASDRAVQP 520

Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD-PDEGPNAVVHYS 725
             S   V + I D ND+PP FES      ++++  +GT +  + AHD  D G N+ V Y 
Sbjct: 521 LMSETTVIVNIVDSNDNPPQFESPNYFTPVAKSVKVGTRLTRVVAHDKKDFGLNSEVEYV 580

Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEI 782
           I GG+ S+ F L+   G      +T+         K + + I A    +PPL     + I
Sbjct: 581 ITGGNSSSKFQLDKSSG-----WITVASSLISDVNKIFMVGITATDRGNPPLSGLTSLRI 635

Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA---YDADVTDKLQYRILSGNNANL 839
            VT+ N + P     Q +     +   VG   R  +    D D+   + Y I SGN+  L
Sbjct: 636 AVTEENHHTPEFSQSQ-VSATIPESLAVGTAIRTLSARDKDKDMNGVITYNITSGNDRGL 694

Query: 840 ILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
             +N  +G ++L+  L+    +   + VS  DG
Sbjct: 695 FSINSRSGVLSLAGPLDFEEKQQHNLRVSAIDG 727



 Score =  282 bits (691), Expect = 1e-73
 Identities = 238/849 (28%), Positives = 385/849 (45%), Gaps = 75/849 (8%)

Query: 13  VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72
           V D ND++PVF    +  ++ E A +GT VL + ++D D+G N  + Y++          
Sbjct: 25  VSDVNDNAPVFSTSTFHTTITEDAPTGTDVLLVNSSDADVGNNGVISYSLS--------- 75

Query: 73  EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132
                            F I+  +G ++T + LDRE+ A Y +LV ATD   P    LSS
Sbjct: 76  ------------GGHGQFSINPATGQIITSSVLDREERANYQLLVVATDGGQP--QGLSS 121

Query: 133 TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192
           +AT+ V + D NDN P+F    Y   +    S     ++  +  TD D G+N+ + Y++I
Sbjct: 122 SATVSVTVADINDNPPRFHHHPYVTHI--PASTAAGSLVFAVTVTDEDAGSNAQLHYSLI 179

Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252
           G +++ +F ID + G ++  + L         L +R +DGG+  +++ T   + +R V  
Sbjct: 180 GRSSE-KFKIDPIRGAITANEKLTGSS--EVTLTVRVKDGGANPKTDMT--TVTVRFVTG 234

Query: 253 NA-PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311
            + P         +  E+ P  + +  V       G    L+Y +     +GN+D    I
Sbjct: 235 GSFPVIKLKERAFTFPESQPANHIVTTVTGSSMRGG---PLSYYIA----SGNLDHAFHI 287

Query: 312 DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371
           D  SG +     LD E   KY L + A D G PP S+                 F    +
Sbjct: 288 DQLSGELSIRHPLDYEHIQKYVLWIEARDQGFPPYSSYEKVEITIQDVNDNYPVFEKDPF 347

Query: 372 EVELAED-EPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
           + ++ E+  P    VV+    D+  + +L Y I  GN    FSI    G   I   +PLD
Sbjct: 348 QADILENLSPQRVLVVSAVDLDSGPNGQLEYSIVDGNKENSFSINRATGE--IRTTRPLD 405

Query: 431 FKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
            ++  +Y L V ATD G   ++    V INI D N+ AP F    ++A+V E+AP+G TV
Sbjct: 406 REKVAQYSLKVKATDWGLPQKNMAVKVLINILDVNDNAPRFSKI-FSATVAENAPVGYTV 464

Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
             V+ TD D G NA        +I  + +         N   G++  N+         + 
Sbjct: 465 TRVTTTDEDAGSNANECQHW-GDICKQPLKFQ------NSTAGSLNINR---------HS 508

Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD- 607
             VTA D  V  L   T V +++VD NDN P F+   Y   + +   VGT +++V A D 
Sbjct: 509 FIVTASDRAVQPLMSETTVIVNIVDSNDNPPQFESPNYFTPVAKSVKVGTRLTRVVAHDK 568

Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
            D GLN  + Y +         F +D +SG I    +L  +      +   A D G PP 
Sbjct: 569 KDFGLNSEVEYVI-TGGNSSSKFQLDKSSGWITVASSLISDVNKIFMVGITATDRGNPPL 627

Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
           S    + I + + N   P F    ++  I E+  +GT I  + A D D+  N V+ Y+I 
Sbjct: 628 SGLTSLRIAVTEENHHTPEFSQSQVSATIPESLAVGTAIRTLSARDKDKDMNGVITYNIT 687

Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW----NDVRVEIL 783
            G+D   FS+ +R G     L     LD+E  ++++ L + A     W    + V V + 
Sbjct: 688 SGNDRGLFSINSRSG----VLSLAGPLDFEE-KQQHNLRVSAIDGG-WIAKTSYVSVTVH 741

Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADV-TDKLQYRILSGNNANLIL 841
           VTDVNDN PV +  +  F   ++  P G    ++ A D D   + +   ++  ++++L +
Sbjct: 742 VTDVNDNPPVFEPDE-YFPVVQENVPSGTTVVKMNAKDGDSGANAVMAYVIQSSDSDLFV 800

Query: 842 LNETTGSMT 850
           ++  TG++T
Sbjct: 801 IDPNTGTIT 809



 Score =  252 bits (618), Expect = 8e-65
 Identities = 206/670 (30%), Positives = 325/670 (48%), Gaps = 52/670 (7%)

Query: 233 GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292
           G PS S T  + + + DVNDNAP F TS F  +++E+ P G  ++ V + DAD G N  +
Sbjct: 11  GVPSLSGTCMVTVFVSDVNDNAPVFSTSTFHTTITEDAPTGTDVLLVNSSDADVGNNGVI 70

Query: 293 TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP-RSATAT 351
           +Y+++     G+     +I+P +G + TS  LDRE +A YQLLV ATDGG P   S++AT
Sbjct: 71  SYSLSG----GHGQ--FSINPATGQIITSSVLDREERANYQLLVVATDGGQPQGLSSSAT 124

Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV--VTLTATDADEDNRLHYEITGGNTR 409
                         F    Y   +      G+ V  VT+T  DA  + +LHY + G ++ 
Sbjct: 125 VSVTVADINDNPPRFHHHPYVTHIPASTAAGSLVFAVTVTDEDAGSNAQLHYSLIGRSSE 184

Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYA-PV 468
            +F I     RG IT  + L    E    LTV   D G    T M  + +      + PV
Sbjct: 185 -KFKIDPI--RGAITANEKLTGSSE--VTLTVRVKDGGANPKTDMTTVTVRFVTGGSFPV 239

Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528
            +      +  E  P    V  V+ +    G    ++Y ++S        + D  F I+ 
Sbjct: 240 IKLKERAFTFPESQPANHIVTTVTGSSMRGG---PLSYYIAS-------GNLDHAFHIDQ 289

Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588
            +G ++    LD E +  Y+L + ARD G P  S    VEI++ DVNDN PVF++  + A
Sbjct: 290 LSGELSIRHPLDYEHIQKYVLWIEARDQGFPPYSSYEKVEITIQDVNDNYPVFEKDPFQA 349

Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648
           +I+E+ L    V  V A D D G NG++ Y +     +E SF I+ A+G IRT + LDRE
Sbjct: 350 DILEN-LSPQRVLVVSAVDLDSGPNGQLEYSI-VDGNKENSFSINRATGEIRTTRPLDRE 407

Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
            VA + LK  A D G P ++  V V I I D+ND+ P F S   +  ++EN+P+G T+  
Sbjct: 408 KVAQYSLKVKATDWGLPQKNMAVKVLINILDVNDNAPRF-SKIFSATVAENAPVGYTVTR 466

Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768
           +   D D G NA         ++   +    +Q   K +  T   L+      ++  ++ 
Sbjct: 467 VTTTDEDAGSNA---------NECQHWGDICKQPL-KFQNSTAGSLNI----NRHSFIVT 512

Query: 769 A---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDA--- 821
           A   A  PL ++  V + + D NDN P  +     F        VG    RV A+D    
Sbjct: 513 ASDRAVQPLMSETTVIVNIVDSNDNPPQFES-PNYFTPVAKSVKVGTRLTRVVAHDKKDF 571

Query: 822 DVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMM 880
            +  +++Y I  GN+++   L++++G +T++  L ++V K+  + ++ TD G   +  + 
Sbjct: 572 GLNSEVEYVITGGNSSSKFQLDKSSGWITVASSLISDVNKIFMVGITATDRGNPPLSGLT 631

Query: 881 QLSVRLITEE 890
            L +  +TEE
Sbjct: 632 SLRI-AVTEE 640



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 67/280 (23%), Positives = 104/280 (37%), Gaps = 30/280 (10%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPL 1369
            C    + C   PC+NG  C +  D Y C C      +D  +   P     G    +  P 
Sbjct: 1493 CDSIINHCECNPCFNGGSCQNRVDGYYCHCP--FDVRDWKEPAPPAPADTGAPAWTTGPG 1550

Query: 1370 LRPIQLPWLNALSIRT-RQRDAFVMSIQLKSGLLHYSYNGETMYLPMATLSDGAWHRIEI 1428
                    L A S+R  R  + + +S     G +  +       +  A LSDG WH +++
Sbjct: 1551 SSASAWTALPADSVRNLRNGNIYYISDVGVLGKVERT-------IVDALLSDGQWHTLQL 1603

Query: 1429 KWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGLLASDVGFFEGCI-- 1486
               G+   + VD G   V+         G  +  + +GG+        +  G F+GC+  
Sbjct: 1604 VKNGSTTLLQVDDGHSRVIQ-HTTQDFGGLGVLTVSLGGIPPGPAQQKTAAG-FDGCLAY 1661

Query: 1487 -----QDVRIGTAQSLLNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEA 1541
                 +++      SL+       +V+ GC+    C  + C     CV  W +  C    
Sbjct: 1662 LKYNGENLPFAGEHSLVTLTKTSSSVKIGCRGPNLCESNPCWDSLMCVNQWYTYQC---- 1717

Query: 1542 GRVGPQCVSACELGPC-GAARCVPDQTPKGYSCACEPGYT 1580
              V P     C   PC     CVPD    G++CAC   YT
Sbjct: 1718 --VPP---GDCASNPCQNQGSCVPD-PHSGFTCACSEFYT 1751



 Score = 50.8 bits (116), Expect = 5e-04
 Identities = 68/324 (20%), Positives = 110/324 (33%), Gaps = 21/324 (6%)

Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRS---GSQCVARRE-GGILCQG--- 1091
            V  F+C CPEGFTG+ CE  + +       +G++C++   G  C+ +    G  C     
Sbjct: 1439 VGGFSCTCPEGFTGMACERDVNECLSNPCKNGALCQNFPGGFNCLCKSGFSGKTCDSIIN 1498

Query: 1092 -CSIDAAYTTAVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNE 1150
             C  +  +    C+ R   +           K           A   T       G  + 
Sbjct: 1499 HCECNPCFNGGSCQNRVDGYYCHCPFDVRDWKE------PAPPAPADTGAPAWTTGPGSS 1552

Query: 1151 RHDFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITM 1210
               + AL   S    R G         + G      V+  + DG WHT+++     T  +
Sbjct: 1553 ASAWTALPADSVRNLRNGNIYYISDVGVLGKVERTIVDALLSDGQWHTLQLVKNGSTTLL 1612

Query: 1211 ILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPT----ETCHRFLDLTGP-LQIG 1265
             +DD    +      DFG           + P   +  T    + C  +L   G  L   
Sbjct: 1613 QVDDGHSRVIQHTTQDFGGLGVLTVSLGGIPPGPAQQKTAAGFDGCLAYLKYNGENLPFA 1672

Query: 1266 GLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNG 1325
            G  ++ +  +  +   +GC      +      +S +  N            C+S PC N 
Sbjct: 1673 GEHSLVTLTKTSSSVKIGCRGPNLCESNPC-WDSLMCVNQWYTYQCVPPGDCASNPCQNQ 1731

Query: 1326 AEC-SDLWDTYICDCKEGHTGKDC 1348
              C  D    + C C E +TGK C
Sbjct: 1732 GSCVPDPHSGFTCACSEFYTGKSC 1755



 Score = 41.9 bits (94), Expect = 0.25
 Identities = 17/43 (39%), Positives = 22/43 (51%)

Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            T A C    + C  +PC+NG  C +L   + C C EG TG  C
Sbjct: 1413 TGALCETDINECQPSPCHNGGTCHNLVGGFSCTCPEGFTGMAC 1455



 Score = 41.5 bits (93), Expect = 0.32
 Identities = 38/162 (23%), Positives = 59/162 (36%), Gaps = 16/162 (9%)

Query: 1533 DSSTCTCEAGRVGPQCVSACELGP-CGAARCVP-----DQTPKGYSCACEPGYT--LTTS 1584
            D   CT    + G  C     +GP   +   VP      +  + Y+C+C PGYT  L  +
Sbjct: 1360 DYDPCTHNPCQNGGSCKRRLGVGPDMRSEESVPVILVFSRPLQPYACSCRPGYTGALCET 1419

Query: 1585 GCIESGKEECPGGWWGGSACGPCACDVTRGY-HPHCNKENGKCHCKENHYKPEGTAECLP 1643
               E     C  G    +  G  +C    G+    C ++  +  C  N  K     +  P
Sbjct: 1420 DINECQPSPCHNGGTCHNLVGGFSCTCPEGFTGMACERDVNE--CLSNPCKNGALCQNFP 1477

Query: 1644 ----CQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681
                C C  +G    +C++    C C P   G +C    + Y
Sbjct: 1478 GGFNCLC-KSGFSGKTCDSIINHCECNPCFNGGSCQNRVDGY 1518



 Score = 40.7 bits (91), Expect = 0.57
 Identities = 34/108 (31%), Positives = 44/108 (40%), Gaps = 12/108 (11%)

Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571
            +C  S C     C       +CTC  G  G  C   V+ C   PC   A C     P G+
Sbjct: 1423 ECQPSPCHNGGTCHNLVGGFSCTCPEGFTGMACERDVNECLSNPCKNGALC--QNFPGGF 1480

Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHC 1619
            +C C+ G++  T   I     EC   + GGS    C   V  GY+ HC
Sbjct: 1481 NCLCKSGFSGKTCDSI-INHCECNPCFNGGS----CQNRVD-GYYCHC 1522


>UniRef50_P33450 Cluster: Cadherin-related tumor suppressor precursor;
            n=6; Coelomata|Rep: Cadherin-related tumor suppressor
            precursor - Drosophila melanogaster (Fruit fly)
          Length = 5147

 Score =  340 bits (835), Expect = 4e-91
 Identities = 294/1059 (27%), Positives = 478/1059 (45%), Gaps = 63/1059 (5%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDI-GKNAEVEYTIELVTADT 69
            I + D ND++P FE   Y  S  E   S   V  + ATD+D  G N+ + Y+++      
Sbjct: 3001 ITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQIIATDRDKQGPNSVISYSLQ------ 3054

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
              P               +VF    +       +   R     Y + V ATD   P    
Sbjct: 3055 -QPSPMFSIDPATG----EVF---SKKAVRFKHSQYVRSPENMYALTVLATDNGKPP--- 3103

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA-DVGANSAIR 188
            L S   +++NI+D ++N P+F +  Y   + +D        I ++ A D  D+G N  + 
Sbjct: 3104 LYSECLVNINIVDAHNNPPKFEQAEYLAPLPQD--AVRGQRIVRVHANDKQDLGTNE-MD 3160

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            Y+++  N    FS+    G ++LVK +       Y LV+RA D G P +S+ T+++I + 
Sbjct: 3161 YSLMTFNLSSIFSVGRHDGWITLVKPIQVPPNTRYELVVRATDRGVPPQSDETRVVIVVT 3220

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
              N + PRF  + +Q  V EN P+G +I+ V A D D G N  L Y+++     GN    
Sbjct: 3221 GENMDTPRFSVNSYQVIVPENEPVGSTILTVGATDDDTGPNGMLRYSISG----GNERQD 3276

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
             ++D R+G +    QLD +   +Y L +T  D G  P S+ A               F  
Sbjct: 3277 FSVDERTGGIVIQQQLDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVNDNPPVFNH 3336

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVA 426
             +Y   + E++P GT V    A D D      +HY          F I +Q+  G I+ A
Sbjct: 3337 KEYHCYIPENKPVGTFVFQAHAADKDSPKNAIIHYAFLPSGPDRHFFIMNQS-NGTISSA 3395

Query: 427  QPLDFKQERRYVLTVSATDSGGRSDT-AMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
               D+++ R Y L + A +     ++ A + +++   N + P F    +   V E + +G
Sbjct: 3396 VSFDYEERRIYTLQIKAKNPDSSMESYANLYVHVLGVNEFYPQFLQPVFHFDVSETSAVG 3455

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
            T V  V ATD D G + ++ Y L         + +D+ F I+  TG I   + LDRET +
Sbjct: 3456 TRVGAVQATDKDSGEDGRVYYLLVG-------SSNDKGFRIDTNTGLIYVARHLDRETQN 3508

Query: 546  GYLLTVTARDGGVPSLSDTTDVE--ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
              +LTV A++ G    +DT + +  IS+ D ND  P F +  YT+ I E A VGT V+ V
Sbjct: 3509 RVVLTVMAKNYGSIRGNDTDEAQVIISIQDGND-PPEFIKHYYTSTISEAAPVGTKVTTV 3567

Query: 604  GATDADVGL-NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
             A D DV   N +  Y +   + ++ SF ID  +G I T   LDRE  +T++L   AID 
Sbjct: 3568 KAIDKDVRTQNNQFSYSIINGNLKQ-SFKIDVQTGEISTASRLDREETSTYNLVIGAIDT 3626

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN-AV 721
            G PPQ+ +  VHI++ED+ND+ P F  + L  YISEN P GT+I  + A DPD   N   
Sbjct: 3627 GLPPQTGSATVHIELEDVNDNGPTFTPEGLNGYISENEPAGTSIMTLIASDPDLPRNGGP 3686

Query: 722  VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781
              Y + GG   +  S++   G  ++   T  D +     +    V  +  P   +   + 
Sbjct: 3687 FTYQLIGGKHKSWLSVDRNSGVVRS--TTSFDREMTPILEAIIEVEDSGKPKQKSQHLLT 3744

Query: 782  ILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLI 840
            I V D NDN    +   I  + +    P       V   D D+    + R L  N A   
Sbjct: 3745 ITVLDQNDNPSTTRSLHIAVSLFNGDLPSNVKLADVRPNDIDIVGDYRCR-LQKNPAQSQ 3803

Query: 841  LLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN-EIKAMMQLSVRLITEEMLLNSITVR 899
            L      +  L    +T  P  +    +  DG + ++ + + ++ +    E L NS+++ 
Sbjct: 3804 LQLAIPRACDLITTSHT-TPIASVFSYTGNDGKHGDVSSKVSVAFQSFNNETLANSVSIM 3862

Query: 900  LNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAE 959
            + +MTA  FL+      ++ + + +   ++ + ++S+ +    +GN  N+          
Sbjct: 3863 VRNMTAYHFLANHYRPILEMIKSRM-SNEDEVILYSLLEGG--SGNSTNLQLL------- 3912

Query: 960  VGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKF 1019
            + V    + +  P +L ER+   R+  + L   +V+   +     + C N   C   ++ 
Sbjct: 3913 MAVRLAKTSYQQPKYLIERLREKRSAFSELLQKEVIVGYEPCSEPDVCENGGVCSATMRL 3972

Query: 1020 GNASGFVNSDS---VLFRPIYPVTSFTCQCPEGFTGVNC 1055
             +A  FV  DS   VL  P   V  ++CQC  GF+G  C
Sbjct: 3973 LDAHSFVIQDSPALVLSGP-RVVHDYSCQCTSGFSGEQC 4010



 Score =  327 bits (803), Expect = 3e-87
 Identities = 267/924 (28%), Positives = 445/924 (48%), Gaps = 71/924 (7%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ V D ND++P F    Y  ++ EGAS GT +  +   D D G N +V Y++       
Sbjct: 1265 KVIVTDVNDNAPEFLRAPYHVTISEGASEGTHITHVFTQDADEGLNGDVYYSLA------ 1318

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                +A              F +D  +G L     LDRE    + ++V A D A  +   
Sbjct: 1319 -KGNEAGQ------------FNLDSATGQLSLGRRLDRESQEIHHLIVVAKDAA--LKHP 1363

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            LSS A+I + ++D+NDN P+F++ +  VSV E  S T   ++ + +A+DAD G NS + +
Sbjct: 1364 LSSNASITIVVLDENDNAPEFTQSSSEVSVLET-SPTGTELM-RFRASDADQGVNSQVVF 1421

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            +I  GN +  F IDS++G + L K LDYE + SY L I A D G+PS S T    + + D
Sbjct: 1422 SISAGNRRDTFHIDSITGSLYLHKPLDYEDITSYTLNITASDCGTPSLSTTVLYNVLVVD 1481

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
             NDN P F ++     + E +P+   IV V A D D G+N +++Y ++ ++         
Sbjct: 1482 DNDNPPIFPSTAIVRQIKEGIPLKTPIVTVTADDPDSGLNGKVSYAISKQEPQLPQGRHF 1541

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX---F 366
             I+  +G ++T  ++DRE+   ++L V ATD   P     +T                 F
Sbjct: 1542 GINTETGVIHTLREIDRESIDTFRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAPVF 1601

Query: 367  MPGQYEV---ELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRG 421
            +     +   + +  +   T V+ + A DAD  +   + YEI  G  +  F +  Q   G
Sbjct: 1602 VSMNAAILPPKFSTSKGSSTAVMQVHAKDADSSSNGLVTYEIVSG-PQELFKL--QRNTG 1658

Query: 422  LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT-------DANNYAPVFEN-AP 473
            +IT      FKQE RY LT+ +TD   +S+    ++ IT        + +  P FE  + 
Sbjct: 1659 IITFTPGPQFKQEVRYQLTLKSTDEAVQSERRSSEVYITIITPGSGGSESSVPQFEQRSK 1718

Query: 474  YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
             + SV+E+ PIGT++L V+A  +    +A+I Y +++  +  +    D+ F I+ + G +
Sbjct: 1719 LSGSVYENEPIGTSILTVTAHLA----SAEIEYFVTNVTATGSRGQVDRLFDIDAKLGIL 1774

Query: 534  TTNKLLDRET-MSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
            +T   LDRE     Y + V A   GG P  S  T V ++V+D ND+ P F    +  N+ 
Sbjct: 1775 STAAELDREAGPEEYEVEVYAIALGGQPRTS-RTKVRVTVLDKNDSPPQFLDTPFVYNVS 1833

Query: 592  EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA 651
            ED  +G ++S + A D D    G + + L   D  +G F+++P++G +  N  LDRE+ +
Sbjct: 1834 EDLQIGHTISTLRAHDPDT--LGSVTFLL--MDGHDGKFLLEPSTGKLILNDTLDRETKS 1889

Query: 652  THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711
             ++L+    DG    Q +     I++ D ND+PP+FE    +F I EN+  G  +G+I A
Sbjct: 1890 KYELRIRVSDG---VQYTEAYATIQVSDTNDNPPLFEDTVYSFDIPENAQRGYQVGQIVA 1946

Query: 712  HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA-- 769
             D D G NA + Y +     ++ FSL  + G     L     LDYE  +  Y L+++A  
Sbjct: 1947 RDADLGQNAQLSYGVVSDWANDVFSLNPQTGM----LTLTARLDYEEVQH-YILIVQAQD 2001

Query: 770  -ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK-- 826
               P L   + V   V D+NDNAP+          +++         V A D D  +   
Sbjct: 2002 NGQPSLSTTITVYCNVLDLNDNAPIFDPMSYSSEVFENVPIATEVVTVSAKDIDSGNNGL 2061

Query: 827  LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886
            ++Y I +G+  +   + ++ G++     L+       T+ V+  D  +E  +  +L    
Sbjct: 2062 IEYSITAGDVDSEFGI-DSNGTIRTRRNLDREHRSTYTLTVTARDCADEFASFSELE--- 2117

Query: 887  ITEEMLLNSITVRLNDMTAEQFLS 910
               ++ L   + R    T ++FL+
Sbjct: 2118 -ETQLKLKYRSPRKYQQTRQEFLA 2140



 Score =  325 bits (799), Expect = 9e-87
 Identities = 276/939 (29%), Positives = 444/939 (47%), Gaps = 103/939 (10%)

Query: 8    HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
            H  I+V D NDH PVFE  +Y A + E A +G+ V ++ ATD+D G NA+V Y  ++++ 
Sbjct: 479  HLIIDVNDVNDHEPVFEKSEYSAVLSELAPTGSFVASITATDEDTGVNAQVHY--DILSG 536

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
            + L                   F +D  +G ++T   LDRE   R TV +  + +    +
Sbjct: 537  NELK-----------------WFSMDPLTGLIVTTGPLDRE--IRDTVELSISARDGGPN 577

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
             + + T  + V I+D+ND  PQFS++   V++ ED       ++A + ATD D G N ++
Sbjct: 578  PKFAYTQ-LKVIILDENDEAPQFSQREQNVTLGED--APPQTIVALMTATDHDQGTNGSV 634

Query: 188  RYAIIGGNTQM---QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQL 243
             +A+     ++   QF++D+L+G ++  + LD E++  Y + + A+D G+P+ +S T  +
Sbjct: 635  TFALAPSVERLYPLQFALDALTGQLTTRRPLDREKMSQYEISVIARDQGAPTPQSATATV 694

Query: 244  LINIRDVNDNAPRFYTSLFQESVSEN---------VPIGYSIVRVQAYDADEGVNAELTY 294
             +N+ DVNDN P+FY   +  S++++         V     ++ V A D D+G NA + Y
Sbjct: 695  WLNVADVNDNDPQFYPRHYIYSLADDDDDIKLKKEVEKERILLHVTASDKDDGDNALIEY 754

Query: 295  TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK--YQLLVTATDGGD--PPRSATA 350
             +     +G   L   +D RSG +   G        K  Y+LLV+A D G     + A  
Sbjct: 755  RLE----SGGEGL-FQLDARSGAISLRGDAPASMHWKPHYKLLVSARDAGQRRSQQDAIV 809

Query: 351  TXXXXXXXXXXXXXXFMPGQYEVELAEDEP------PGTPV--VTLTATDADEDNRLHYE 402
                              G YE ++ ED        P   V  V + +T+   ++ + Y+
Sbjct: 810  EIVLKSKLEMLECGQAQAGGYEFQMVEDHEQQRNSQPNREVGIVQVKSTNGKANSHIEYD 869

Query: 403  ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA--------M 454
            I  G+    F I +++GR  IT A+PLD +++  Y LT+ A+ S   S  A        +
Sbjct: 870  IIQGDRAQNFRIDTRSGR--ITTARPLDREEQANYRLTILASSSSSSSAAASSVSYGQCI 927

Query: 455  VQINITDANNYAPVF----ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510
            V I I D N+ APVF    E+ P T S+ E+A +G  + +    D D G+N++I+YSL++
Sbjct: 928  VNIAIIDLNDNAPVFALDRESEP-TISLPENAAVGQEIYLSRVRDRDAGVNSRISYSLTN 986

Query: 511  EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570
                    + +QQF I P TG +   + +  E  S   + + A D G P LS    + + 
Sbjct: 987  --------NPNQQFRIGPVTGVLYLQRPIRAEPGSLIHVELMATDAGSPPLSSKLSLSVL 1038

Query: 571  VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630
            + DVND+ PVF    Y  ++ E   V T    + ATD D+G NGRI YE+  +   E  F
Sbjct: 1039 IADVNDHTPVFDHTSYETSLPETTKVNTRFFALAATDIDLGDNGRISYEI-IEGNTERMF 1097

Query: 631  VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690
             + P  G +     LDRE    + L     D G P +SS V V I + D ND+ P F + 
Sbjct: 1098 GVFP-DGYLFVRAPLDREERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQFTNS 1156

Query: 691  CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA---- 746
              TF I EN+P  T +G++ A D D G NA + +++     +  F+++TR G  K     
Sbjct: 1157 TFTFSIPENAPADTFVGKLTAVDRDIGRNAELSFTL--SSQTQDFTIDTRNGFIKTLRPF 1214

Query: 747  --ELVTMVDLDYE----------SPRKKYELVIRAAS----PPLWNDVRVEILVTDVNDN 790
              E +  V  + E          S    Y L+    S    P L + V+V+++VTDVNDN
Sbjct: 1215 DREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDN 1274

Query: 791  APVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGS 848
            AP            +          V   DAD  +   + Y +  GN A    L+  TG 
Sbjct: 1275 APEFLRAPYHVTISEGASEGTHITHVFTQDADEGLNGDVYYSLAKGNEAGQFNLDSATGQ 1334

Query: 849  MTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887
            ++L  +L+    ++  + V   D   +       S+ ++
Sbjct: 1335 LSLGRRLDRESQEIHHLIVVAKDAALKHPLSSNASITIV 1373



 Score =  325 bits (799), Expect = 9e-87
 Identities = 257/862 (29%), Positives = 414/862 (48%), Gaps = 71/862 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGA--SSGTTVLTLKATDQDIGK-NAEVEYTIELVTA 67
            IN+LD ND+ P F    Y A V E     +G  VLT+ A D D    N++V Y ++    
Sbjct: 2372 INILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLK--EG 2429

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
            D+                  D+FRI+  SG +     LDRE+ + YT+ + A D  SP  
Sbjct: 2430 DS------------------DLFRINASSGDIALLKPLDREQQSEYTLTLVAMDTGSP-- 2469

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
              L+ T  + V + D NDN P F  ++Y  +V E++       +   +ATD D G N+ +
Sbjct: 2470 -PLTGTGIVRVEVQDINDNDPVFELQSYHATVRENL--PSGTHVLTPRATDKDEGLNAKL 2526

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG-SPSRSNTTQLLIN 246
            R+ ++G +   +F IDS +G++S   TLD E+   Y L + AQD   +  R+++  L I+
Sbjct: 2527 RFNLLGEHMH-RFHIDSETGEISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTIS 2585

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            + DVNDN P+F ++ +  +V E +  G  +   +A D D+G NA + YT++ +D      
Sbjct: 2586 VSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALDLDDGENAVVHYTISGRD-----Q 2640

Query: 307  LPITIDPRSGWVYTSGQLDRETQA----KYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
                I+ ++G V T  +L  +T++     Y ++++A D G+   S+ A            
Sbjct: 2641 HYFDINTKTGVVSTKLELKTKTKSHDDLTYTIVISAMDQGEQSLSSKAELTVILRPPELF 2700

Query: 363  XXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGR 420
                        ++ED  PG  +  ++AT   +    ++ Y I GG      S+      
Sbjct: 2701 PTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRYAIAGGIMGD--SLRVDPNS 2758

Query: 421  GLITVAQP-LDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTAS 477
            GL++V Q  LD++    Y + + A D    S     ++ +N+TDAN+ APV E   Y A 
Sbjct: 2759 GLLSVGQDGLDYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQLIYNAE 2818

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            V E+      + VV A+D D G N  + Y L ++         D  F I  ++G I T  
Sbjct: 2819 VLEEESPPQLIAVVKASDRDSGDNGNVIYRLQNDF--------DGTFEIT-ESGEIYTRM 2869

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
             LDRE +  Y   V A D GVP ++ T  V + ++D NDN P F  +L++ N+ E+A +G
Sbjct: 2870 RLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPKF-TRLFSLNVTENAEIG 2928

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
            + V +V ++D D+G N    Y       E+  F I+P SG I     LDRE    + LK 
Sbjct: 2929 SFVIRVTSSDLDLGANANASYSFSENPGEK--FRIEPQSGNITVAGHLDREQQDEYILKV 2986

Query: 658  VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-E 716
            VA DG    ++    + I I+D ND+ P FE    +F   E       +G+I A D D +
Sbjct: 2987 VASDGAWRAETP---ITITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQIIATDRDKQ 3043

Query: 717  GPNAVVHYSIKGGDDSNSFSLETRQGS-DKAELVTMVDLDY-ESPRKKYELVIRA---AS 771
            GPN+V+ YS++    S  FS++   G     + V      Y  SP   Y L + A     
Sbjct: 3044 GPNSVISYSLQ--QPSPMFSIDPATGEVFSKKAVRFKHSQYVRSPENMYALTVLATDNGK 3101

Query: 772  PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD-ADV-TDKLQY 829
            PPL+++  V I + D ++N P  +  + +    +D        RV A D  D+ T+++ Y
Sbjct: 3102 PPLYSECLVNINIVDAHNNPPKFEQAEYLAPLPQDAVRGQRIVRVHANDKQDLGTNEMDY 3161

Query: 830  RILSGNNANLILLNETTGSMTL 851
             +++ N +++  +    G +TL
Sbjct: 3162 SLMTFNLSSIFSVGRHDGWITL 3183



 Score =  314 bits (770), Expect = 3e-83
 Identities = 241/796 (30%), Positives = 384/796 (48%), Gaps = 64/796 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I +LD ND+SPVF+ +QY ASV E AS G  VL + ATD D G N  + Y+I  V  D  
Sbjct: 2266 IRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGRIRYSI--VLGDQN 2323

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +                  F I   +G +    +L+ E+++RY++ V+A D A  + +  
Sbjct: 2324 HD-----------------FSISEDTGVVRVAKNLNYERLSRYSLTVRAEDCA--LENPA 2364

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA-NSAIRY 189
              TA + +NI+D NDN P F +  Y   V E+    +   +  + A DAD    NS +RY
Sbjct: 2365 GDTAELTINILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRY 2424

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             +  G++ + F I++ SGD++L+K LD EQ   Y L + A D GSP  + T  + + ++D
Sbjct: 2425 FLKEGDSDL-FRINASSGDIALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQD 2483

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            +NDN P F    +  +V EN+P G  ++  +A D DEG+NA+L + +      G      
Sbjct: 2484 INDNDPVFELQSYHATVRENLPSGTHVLTPRATDKDEGLNAKLRFNLL-----GEHMHRF 2538

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPPRSATATXXXXXXXXXXXXXXFMP 368
             ID  +G + T+  LDRE  + Y L + A D     PR+++                F  
Sbjct: 2539 HIDSETGEISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDS 2598

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVA 426
              Y V + E    G  V    A D D+     +HY I+G +    F I ++ G     V+
Sbjct: 2599 TTYNVAVPERISKGEFVFGARALDLDDGENAVVHYTISGRDQH-YFDINTKTG----VVS 2653

Query: 427  QPLDFKQERR------YVLTVSATDSGGRSDTAMVQIN-ITDANNYAPVFEN-APYTASV 478
              L+ K + +      Y + +SA D G +S ++  ++  I       P F   A    ++
Sbjct: 2654 TKLELKTKTKSHDDLTYTIVISAMDQGEQSLSSKAELTVILRPPELFPTFAYMANSHFAM 2713

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             ED   G  +  VSAT    G+  +I Y+++  I  +++        ++P +G ++  + 
Sbjct: 2714 SEDVRPGKMITKVSATSPKKGLVGKIRYAIAGGIMGDSLR-------VDPNSGLLSVGQD 2766

Query: 539  -LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
             LD E    Y + + A DG  PSL   T + ++V D NDN PV +Q +Y A ++E+    
Sbjct: 2767 GLDYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQLIYNAEVLEEESPP 2826

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
              ++ V A+D D G NG + Y L  ++  +G+F I   SG I T   LDRE +  +    
Sbjct: 2827 QLIAVVKASDRDSGDNGNVIYRL--QNDFDGTFEI-TESGEIYTRMRLDREEIGDYAFVV 2883

Query: 658  VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
             A+D G P  + T  V + + D ND+PP F +   +  ++EN+ IG+ +  + + D D G
Sbjct: 2884 EAVDQGVPHMTGTASVLLHLLDKNDNPPKF-TRLFSLNVTENAEIGSFVIRVTSSDLDLG 2942

Query: 718  PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN- 776
             NA   YS    +    F +E + G+    +     LD E  + +Y L +  AS   W  
Sbjct: 2943 ANANASYSF-SENPGEKFRIEPQSGN----ITVAGHLDREQ-QDEYILKV-VASDGAWRA 2995

Query: 777  DVRVEILVTDVNDNAP 792
            +  + I + D NDNAP
Sbjct: 2996 ETPITITIQDQNDNAP 3011



 Score =  312 bits (766), Expect = 9e-83
 Identities = 252/917 (27%), Positives = 415/917 (45%), Gaps = 88/917 (9%)

Query: 13   VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72
            + D NDH+PVF+   YE S+ E     T    L ATD D+G N  + Y  E++  +T   
Sbjct: 1039 IADVNDHTPVFDHTSYETSLPETTKVNTRFFALAATDIDLGDNGRISY--EIIEGNT--- 1093

Query: 73   EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132
                          + +F +    G L  RA LDRE+   Y + V   D   P     SS
Sbjct: 1094 --------------ERMFGVFP-DGYLFVRAPLDREERDYYALTVSCRDAGQPSR---SS 1135

Query: 133  TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192
               + +++ID+NDN PQF+  T+T S+ E+     +  + K+ A D D+G N+ + + + 
Sbjct: 1136 VVPVVIHVIDENDNAPQFTNSTFTFSIPENAPA--DTFVGKLTAVDRDIGRNAELSFTL- 1192

Query: 193  GGNTQMQFSIDSLSGDVSLVKTLDYEQV---------------------RSYRLV-IRAQ 230
               TQ  F+ID+ +G +  ++  D E +                      +Y L+     
Sbjct: 1193 SSQTQ-DFTIDTRNGFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVS 1251

Query: 231  DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290
            D G P   +  ++ + + DVNDNAP F  + +  ++SE    G  I  V   DADEG+N 
Sbjct: 1252 DNGIPRLQDKVKVKVIVTDVNDNAPEFLRAPYHVTISEGASEGTHITHVFTQDADEGLNG 1311

Query: 291  ELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPPRSAT 349
            ++ Y++   +  G  +L    D  +G +    +LDRE+Q  + L+V A D     P S+ 
Sbjct: 1312 DVYYSLAKGNEAGQFNL----DSATGQLSLGRRLDRESQEIHHLIVVAKDAALKHPLSSN 1367

Query: 350  ATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGN 407
            A+              F     EV + E  P GT ++   A+DAD+  ++++ + I+ GN
Sbjct: 1368 ASITIVVLDENDNAPEFTQSSSEVSVLETSPTGTELMRFRASDADQGVNSQVVFSISAGN 1427

Query: 408  TRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNY 465
             R  F I S  G   + + +PLD++    Y L ++A+D G    S T +  + + D N+ 
Sbjct: 1428 RRDTFHIDSITGS--LYLHKPLDYEDITSYTLNITASDCGTPSLSTTVLYNVLVVDDNDN 1485

Query: 466  APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525
             P+F +      + E  P+ T ++ V+A D D G+N +++Y++S +   E      + F 
Sbjct: 1486 PPIFPSTAIVRQIKEGIPLKTPIVTVTADDPDSGLNGKVSYAISKQ---EPQLPQGRHFG 1542

Query: 526  INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS---LSDTTDVEISVVDVNDNEPVF- 581
            IN +TG I T + +DRE++  + LTV A D   PS   LS    V + V D+NDN PVF 
Sbjct: 1543 INTETGVIHTLREIDRESIDTFRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAPVFV 1602

Query: 582  --KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639
                 +            T+V QV A DAD   NG + YE+    +E   F +   +G+I
Sbjct: 1603 SMNAAILPPKFSTSKGSSTAVMQVHAKDADSSSNGLVTYEIVSGPQE--LFKLQRNTGII 1660

Query: 640  RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI-----EDINDSPPVFES-DCLT 693
                    +    + L   + D     +  +  V+I I          S P FE    L+
Sbjct: 1661 TFTPGPQFKQEVRYQLTLKSTDEAVQSERRSSEVYITIITPGSGGSESSVPQFEQRSKLS 1720

Query: 694  FYISENSPIGTTIGEIRAH-DPDEGPNAVVHYSIKG--GDDSNSFSLETRQGSDKAELVT 750
              + EN PIGT+I  + AH    E    V + +  G  G     F ++ + G     L T
Sbjct: 1721 GSVYENEPIGTSILTVTAHLASAEIEYFVTNVTATGSRGQVDRLFDIDAKLGI----LST 1776

Query: 751  MVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC 807
              +LD E+  ++YE+ + A      P  +  +V + V D ND+ P   D   ++N  +D 
Sbjct: 1777 AAELDREAGPEEYEVEVYAIALGGQPRTSRTKVRVTVLDKNDSPPQFLDTPFVYNVSEDL 1836

Query: 808  FPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867
                    + A+D D    + + ++ G++    LL  +TG + L+  L+        + +
Sbjct: 1837 QIGHTISTLRAHDPDTLGSVTFLLMDGHDGK-FLLEPSTGKLILNDTLDRETKSKYELRI 1895

Query: 868  SVTDGVNEIKAMMQLSV 884
             V+DGV   +A   + V
Sbjct: 1896 RVSDGVQYTEAYATIQV 1912



 Score =  309 bits (759), Expect = 6e-82
 Identities = 243/841 (28%), Positives = 388/841 (46%), Gaps = 61/841 (7%)

Query: 90   FRIDGRSGALLTRASLDREKVARY--TVLVKATDQASPVSDRLS-STATIHVNIIDDNDN 146
            FRID RSG + T   LDRE+ A Y  T+L  ++  +S  +  +S     +++ IID NDN
Sbjct: 879  FRIDTRSGRITTARPLDREEQANYRLTILASSSSSSSAAASSVSYGQCIVNIAIIDLNDN 938

Query: 147  YPQFS---EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSID 203
             P F+   E   T+S+ E+ +V     +++++  D D G NS I Y++   N   QF I 
Sbjct: 939  APVFALDRESEPTISLPENAAVGQEIYLSRVR--DRDAGVNSRISYSLTN-NPNQQFRIG 995

Query: 204  SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263
             ++G + L + +  E      + + A D GSP  S+   L + I DVND+ P F  + ++
Sbjct: 996  PVTGVLYLQRPIRAEPGSLIHVELMATDAGSPPLSSKLSLSVLIADVNDHTPVFDHTSYE 1055

Query: 264  ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323
             S+ E   +      + A D D G N  ++Y + +    GN +    + P  G+++    
Sbjct: 1056 TSLPETTKVNTRFFALAATDIDLGDNGRISYEIIE----GNTERMFGVFP-DGYLFVRAP 1110

Query: 324  LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383
            LDRE +  Y L V+  D G P RS+                 F    +   + E+ P  T
Sbjct: 1111 LDREERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQFTNSTFTFSIPENAPADT 1170

Query: 384  PVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG----------RGLITVAQPLDFKQ 433
             V  LTA D D         T  +    F+I ++NG            L+ V++  +   
Sbjct: 1171 FVGKLTAVDRDIGRNAELSFTLSSQTQDFTIDTRNGFIKTLRPFDREALVKVSRNAEASG 1230

Query: 434  ER---------RYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFED 481
            E           Y+L  +     G     D   V++ +TD N+ AP F  APY  ++ E 
Sbjct: 1231 EDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPEFLRAPYHVTISEG 1290

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
            A  GT +  V   D+D G+N  + YSL+    NEA      QF ++  TG ++  + LDR
Sbjct: 1291 ASEGTHITHVFTQDADEGLNGDVYYSLAK--GNEA-----GQFNLDSATGQLSLGRRLDR 1343

Query: 542  ETMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
            E+   + L V A+D  +   LS    + I V+D NDN P F Q     +++E +  GT +
Sbjct: 1344 ESQEIHHLIVVAKDAALKHPLSSNASITIVVLDENDNAPEFTQSSSEVSVLETSPTGTEL 1403

Query: 601  SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
             +  A+DAD G+N ++ + +   +R + +F ID  +G +  +K LD E + ++ L   A 
Sbjct: 1404 MRFRASDADQGVNSQVVFSISAGNRRD-TFHIDSITGSLYLHKPLDYEDITSYTLNITAS 1462

Query: 661  DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
            D GTP  S+TV+ ++ + D ND+PP+F S  +   I E  P+ T I  + A DPD G N 
Sbjct: 1463 DCGTPSLSTTVLYNVLVVDDNDNPPIFPSTAIVRQIKEGIPLKTPIVTVTADDPDSGLNG 1522

Query: 721  VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASP---PL 774
             V Y+I   +            ++   + T+ ++D ES    + L + A   A P    L
Sbjct: 1523 KVSYAISKQEPQLPQGRHFGINTETGVIHTLREIDRES-IDTFRLTVVATDRAQPSERQL 1581

Query: 775  WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG---PFGRVPAYDADVTDK--LQY 829
              +  V ++V D+NDNAPV           K     G      +V A DAD +    + Y
Sbjct: 1582 STEKLVTVIVEDINDNAPVFVSMNAAILPPKFSTSKGSSTAVMQVHAKDADSSSNGLVTY 1641

Query: 830  RILSGNNANLILLNETTGSMTLS--PQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887
             I+SG    L  L   TG +T +  PQ    V    T++ S  + V   +   ++ + +I
Sbjct: 1642 EIVSGPQ-ELFKLQRNTGIITFTPGPQFKQEVRYQLTLK-STDEAVQSERRSSEVYITII 1699

Query: 888  T 888
            T
Sbjct: 1700 T 1700



 Score =  309 bits (759), Expect = 6e-82
 Identities = 255/895 (28%), Positives = 414/895 (46%), Gaps = 65/895 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I + D ND  PVF +   E ++ E  +  T V+ +KA D D G+N  ++Y ++    + +
Sbjct: 2155 ILIKDVNDEVPVF-ISANETAIMENVAINTVVIAVKAVDNDEGRNGYIDYLMKEARDEDM 2213

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
               D               F ++   G L    +LDRE  + Y + + A D+  P     
Sbjct: 2214 GQSDPL------------PFSLNPTDGQLRVVDALDRELRSSYLLNITARDRGEPPQ--- 2258

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S+ + + + I+D+NDN P F  K Y+ SV E+ S+    ++ ++ ATD D GAN  IRY+
Sbjct: 2259 STESQLLIRILDENDNSPVFDPKQYSASVAENASI--GAMVLQVSATDVDEGANGRIRYS 2316

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLINIRD 249
            I+ G+    FSI   +G V + K L+YE++  Y L +RA+D    +   +T +L INI D
Sbjct: 2317 IVLGDQNHDFSISEDTGVVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTINILD 2376

Query: 250  VNDNAPRFYTSLFQESVSENV--PIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYTGNVD 306
            +NDN P F  S +   V EN   P G  ++ V AYDAD   +N+++ Y + +    G+ D
Sbjct: 2377 INDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKE----GDSD 2432

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
            L   I+  SG +     LDRE Q++Y L + A D G PP + T                F
Sbjct: 2433 L-FRINASSGDIALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVF 2491

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLIT 424
                Y   + E+ P GT V+T  ATD DE  + +L + + G +   RF I S+ G   I+
Sbjct: 2492 ELQSYHATVRENLPSGTHVLTPRATDKDEGLNAKLRFNLLGEHMH-RFHIDSETGE--IS 2548

Query: 425  VAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
             A  LD ++   Y LT+ A DS     R+ +  + I+++D N+  P F++  Y  +V E 
Sbjct: 2549 TATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAVPER 2608

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
               G  V    A D D G NA + Y++S              F IN +TG ++T   L  
Sbjct: 2609 ISKGEFVFGARALDLDDGENAVVHYTIS--------GRDQHYFDINTKTGVVSTKLELKT 2660

Query: 542  ETMS----GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM-EDALV 596
            +T S     Y + ++A D G  SLS   ++ + ++   +  P F     +   M ED   
Sbjct: 2661 KTKSHDDLTYTIVISAMDQGEQSLSSKAELTV-ILRPPELFPTFAYMANSHFAMSEDVRP 2719

Query: 597  GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK-ALDRESVATHDL 655
            G  +++V AT    GL G+I Y +      + S  +DP SG++   +  LD E    +++
Sbjct: 2720 GKMITKVSATSPKKGLVGKIRYAIAGGIMGD-SLRVDPNSGLLSVGQDGLDYELTHLYEI 2778

Query: 656  KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
               A DG TP   S  ++ + + D ND+ PV E       + E       I  ++A D D
Sbjct: 2779 WIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQLIYNAEVLEEESPPQLIAVVKASDRD 2838

Query: 716  EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---P 772
             G N  V Y ++  D   +F +     ++  E+ T + LD E     Y  V+ A     P
Sbjct: 2839 SGDNGNVIYRLQ-NDFDGTFEI-----TESGEIYTRMRLDREE-IGDYAFVVEAVDQGVP 2891

Query: 773  PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVTDKLQYRI 831
             +     V + + D NDN P  K  ++   N  +   +G F  RV + D D+        
Sbjct: 2892 HMTGTASVLLHLLDKNDNPP--KFTRLFSLNVTENAEIGSFVIRVTSSDLDLGANANASY 2949

Query: 832  -LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVR 885
              S N      +   +G++T++  L+        ++V  +DG    +  + ++++
Sbjct: 2950 SFSENPGEKFRIEPQSGNITVAGHLDREQQDEYILKVVASDGAWRAETPITITIQ 3004



 Score =  307 bits (753), Expect = 3e-81
 Identities = 258/827 (31%), Positives = 392/827 (47%), Gaps = 62/827 (7%)

Query: 12   NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71
            NVLD ND++P+F+   Y + V E     T V+T+ A D D G N  +EY+I     D+  
Sbjct: 2016 NVLDLNDNAPIFDPMSYSSEVFENVPIATEVVTVSAKDIDSGNNGLIEYSITAGDVDSEF 2075

Query: 72   PEDAXXXXXXXXXXVQD-----VFRIDGRSGA--LLTRASLDREKVA---RYTVLVKATD 121
              D+           ++        +  R  A    + + L+  ++    R     + T 
Sbjct: 2076 GIDSNGTIRTRRNLDREHRSTYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQQTR 2135

Query: 122  Q---ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178
            Q   A     RLSST  + + I D ND  P F     T ++ E++++  N V+  +KA D
Sbjct: 2136 QEFLAHQKQQRLSSTVKVTILIKDVNDEVPVFISANET-AIMENVAI--NTVVIAVKAVD 2192

Query: 179  ADVGANSAIRYAI-------IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD 231
             D G N  I Y +       +G +  + FS++   G + +V  LD E   SY L I A+D
Sbjct: 2193 NDEGRNGYIDYLMKEARDEDMGQSDPLPFSLNPTDGQLRVVDALDRELRSSYLLNITARD 2252

Query: 232  GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE 291
             G P +S  +QLLI I D NDN+P F    +  SV+EN  IG  +++V A D DEG N  
Sbjct: 2253 RGEPPQSTESQLLIRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGR 2312

Query: 292  LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPPRSATA 350
            + Y++   D   N D  I+ D  +G V  +  L+ E  ++Y L V A D   + P   TA
Sbjct: 2313 IRYSIVLGDQ--NHDFSISED--TGVVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTA 2368

Query: 351  TXXXXXXXXXXXXXXFMPGQYEVELAED--EPPGTPVVTLTATDADE---DNRLHYEITG 405
                           F+   Y   + E+   P G  V+T+ A DAD    ++++ Y +  
Sbjct: 2369 ELTINILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKE 2428

Query: 406  GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDAN 463
            G++   F I + +G   I + +PLD +Q+  Y LT+ A D+G    + T +V++ + D N
Sbjct: 2429 GDS-DLFRINASSGD--IALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDIN 2485

Query: 464  NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523
            +  PVFE   Y A+V E+ P GT VL   ATD D G+NA++ ++L  E        H  +
Sbjct: 2486 DNDPVFELQSYHATVRENLPSGTHVLTPRATDKDEGLNAKLRFNLLGE--------HMHR 2537

Query: 524  FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFK 582
            F I+ +TG I+T   LDRE  S Y LT+ A+D  +    + + ++ ISV DVNDN P F 
Sbjct: 2538 FHIDSETGEISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFD 2597

Query: 583  QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642
               Y   + E    G  V    A D D G N  +HY +  +D+    F I+  +GV+ T 
Sbjct: 2598 STTYNVAVPERISKGEFVFGARALDLDDGENAVVHYTISGRDQH--YFDINTKTGVVSTK 2655

Query: 643  KALDRESVATHDLKAV----AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698
              L  ++ +  DL       A+D G    SS   + + +      P         F +SE
Sbjct: 2656 LELKTKTKSHDDLTYTIVISAMDQGEQSLSSKAELTVILRPPELFPTFAYMANSHFAMSE 2715

Query: 699  NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758
            +   G  I ++ A  P +G    + Y+I GG   +S  ++   G      V    LDYE 
Sbjct: 2716 DVRPGKMITKVSATSPKKGLVGKIRYAIAGGIMGDSLRVDPNSG---LLSVGQDGLDYEL 2772

Query: 759  PRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN 802
                YE+ I AA   +P L +   + + VTD NDNAPVM+  Q+I+N
Sbjct: 2773 TH-LYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVME--QLIYN 2816



 Score =  299 bits (733), Expect = 9e-79
 Identities = 268/906 (29%), Positives = 416/906 (45%), Gaps = 80/906 (8%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            ++  I+V D ND+ P F+   Y  +V E  S G  V   +A D D G+NA V YTI    
Sbjct: 2580 VNLTISVSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALDLDDGENAVVHYTI---- 2635

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR----YTVLVKATDQ 122
                +  D            Q  F I+ ++G + T+  L  +  +     YT+++ A DQ
Sbjct: 2636 ----SGRD------------QHYFDINTKTGVVSTKLELKTKTKSHDDLTYTIVISAMDQ 2679

Query: 123  ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT-VSVDEDISVTDNPVIAKIKATDADV 181
                   LSS A + V I+   + +P F+    +  ++ ED  V    +I K+ AT    
Sbjct: 2680 G---EQSLSSKAELTV-ILRPPELFPTFAYMANSHFAMSED--VRPGKMITKVSATSPKK 2733

Query: 182  GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNT 240
            G    IRYAI GG       +D  SG +S+ +  LDYE    Y + I A DG +PS  + 
Sbjct: 2734 GLVGKIRYAIAGGIMGDSLRVDPNSGLLSVGQDGLDYELTHLYEIWIEAADGDTPSLRSV 2793

Query: 241  TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
            T + +N+ D NDNAP     ++   V E       I  V+A D D G N  + Y +   D
Sbjct: 2794 TLITLNVTDANDNAPVMEQLIYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRL-QND 2852

Query: 301  YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
            + G  ++       SG +YT  +LDRE    Y  +V A D G P  + TA+         
Sbjct: 2853 FDGTFEI-----TESGEIYTRMRLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKN 2907

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG-RFSITSQNG 419
                 F    + + + E+   G+ V+ +T++D D     +   +     G +F I  Q+G
Sbjct: 2908 DNPPKF-TRLFSLNVTENAEIGSFVIRVTSSDLDLGANANASYSFSENPGEKFRIEPQSG 2966

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479
               ITVA  LD +Q+  Y+L V A+D   R++T  + I I D N+ AP FE++ Y+ S  
Sbjct: 2967 N--ITVAGHLDREQQDEYILKVVASDGAWRAETP-ITITIQDQNDNAPEFEHSFYSFSFP 3023

Query: 480  EDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
            E       V  + ATD D  G N+ I+YSL               F I+P TG + + K 
Sbjct: 3024 ELQQSIALVGQIIATDRDKQGPNSVISYSLQQP---------SPMFSIDPATGEVFSKKA 3074

Query: 539  LD-------RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
            +        R   + Y LTV A D G P L     V I++VD ++N P F+Q  Y A + 
Sbjct: 3075 VRFKHSQYVRSPENMYALTVLATDNGKPPLYSECLVNINIVDAHNNPPKFEQAEYLAPLP 3134

Query: 592  EDALVGTSVSQVGATD-ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650
            +DA+ G  + +V A D  D+G N  + Y L   +     F +    G I   K +     
Sbjct: 3135 QDAVRGQRIVRVHANDKQDLGTN-EMDYSLMTFNL-SSIFSVGRHDGWITLVKPIQVPPN 3192

Query: 651  ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710
              ++L   A D G PPQS    V I +   N   P F  +     + EN P+G+TI  + 
Sbjct: 3193 TRYELVVRATDRGVPPQSDETRVVIVVTGENMDTPRFSVNSYQVIVPENEPVGSTILTVG 3252

Query: 711  AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770
            A D D GPN ++ YSI GG++   FS++ R G     +V    LDY+   ++Y L I   
Sbjct: 3253 ATDDDTGPNGMLRYSISGGNERQDFSVDERTGG----IVIQQQLDYDL-IQEYHLNITVQ 3307

Query: 771  S---PPLWNDVRVEILVTDVNDNAPVM--KDFQIIFNNYKDCFPVGPF-GRVPAYDADVT 824
                 PL +   + I++TDVNDN PV   K++       K   PVG F  +  A D D  
Sbjct: 3308 DLGYHPLSSVAMLTIILTDVNDNPPVFNHKEYHCYIPENK---PVGTFVFQAHAADKDSP 3364

Query: 825  DK--LQYRIL-SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQ 881
                + Y  L SG + +  ++N++ G+++ +   +    ++ T+++   +  + +++   
Sbjct: 3365 KNAIIHYAFLPSGPDRHFFIMNQSNGTISSAVSFDYEERRIYTLQIKAKNPDSSMESYAN 3424

Query: 882  LSVRLI 887
            L V ++
Sbjct: 3425 LYVHVL 3430



 Score =  298 bits (732), Expect = 1e-78
 Identities = 265/906 (29%), Positives = 428/906 (47%), Gaps = 88/906 (9%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ V D ND+ PVFE+Q Y A+VRE   SGT VLT +ATD+D G NA++ + +     + 
Sbjct: 2478 RVEVQDINDNDPVFELQSYHATVRENLPSGTHVLTPRATDKDEGLNAKLRFNL---LGEH 2534

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            ++                  F ID  +G + T  +LDRE+ + Y + + A D  S +++ 
Sbjct: 2535 MHR-----------------FHIDSETGEISTATTLDREETSVYHLTLMAQD--SSITEP 2575

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             +S+  + +++ D NDN P+F   TY V+V E IS      +   +A D D G N+ + Y
Sbjct: 2576 RASSVNLTISVSDVNDNIPKFDSTTYNVAVPERIS--KGEFVFGARALDLDDGENAVVHY 2633

Query: 190  AIIGGNTQMQFSIDSLSGDVSL-----VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
              I G  Q  F I++ +G VS       KT  ++ + +Y +VI A D G  S S+  +L 
Sbjct: 2634 T-ISGRDQHYFDINTKTGVVSTKLELKTKTKSHDDL-TYTIVISAMDQGEQSLSSKAELT 2691

Query: 245  INIRDVNDNAPRF-YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
            + +R   +  P F Y +    ++SE+V  G  I +V A    +G+  ++ Y +      G
Sbjct: 2692 VILRP-PELFPTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRYAIAG----G 2746

Query: 304  NVDLPITIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
             +   + +DP SG + + GQ  LD E    Y++ + A DG  P   +             
Sbjct: 2747 IMGDSLRVDPNSG-LLSVGQDGLDYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDAND 2805

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419
                     Y  E+ E+E P   +  + A+D D  ++  + Y +   +  G F IT    
Sbjct: 2806 NAPVMEQLIYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRLQ-NDFDGTFEITES-- 2862

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477
             G I     LD ++   Y   V A D G    + TA V +++ D N+  P F    ++ +
Sbjct: 2863 -GEIYTRMRLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPKFTRL-FSLN 2920

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            V E+A IG+ V+ V+++D D+G NA  +YS S         +  ++F I PQ+G IT   
Sbjct: 2921 VTENAEIGSFVIRVTSSDLDLGANANASYSFSE--------NPGEKFRIEPQSGNITVAG 2972

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
             LDRE    Y+L V A DG   +    T + I++ D NDN P F+   Y+ +  E     
Sbjct: 2973 HLDREQQDEYILKVVASDG---AWRAETPITITIQDQNDNAPEFEHSFYSFSFPELQQSI 3029

Query: 598  TSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD-------RES 649
              V Q+ ATD D  G N  I Y L    +    F IDPA+G + + KA+        R  
Sbjct: 3030 ALVGQIIATDRDKQGPNSVISYSL---QQPSPMFSIDPATGEVFSKKAVRFKHSQYVRSP 3086

Query: 650  VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
               + L  +A D G PP  S  +V+I I D +++PP FE       + +++  G  I  +
Sbjct: 3087 ENMYALTVLATDNGKPPLYSECLVNINIVDAHNNPPKFEQAEYLAPLPQDAVRGQRIVRV 3146

Query: 710  RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
             A+D  +     + YS+   + S+ FS+    G      +T+V      P  +YELV+RA
Sbjct: 3147 HANDKQDLGTNEMDYSLMTFNLSSIFSVGRHDG-----WITLVKPIQVPPNTRYELVVRA 3201

Query: 770  AS---PPLWNDVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFPVG-PFGRVPAYDADV 823
                 PP  ++ RV I+VT  N + P   +  +Q+I    +   PVG     V A D D 
Sbjct: 3202 TDRGVPPQSDETRVVIVVTGENMDTPRFSVNSYQVIVPENE---PVGSTILTVGATDDDT 3258

Query: 824  --TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMM 880
                 L+Y I  GN      ++E TG + +  QL+ ++ +   + ++V D G + + ++ 
Sbjct: 3259 GPNGMLRYSISGGNERQDFSVDERTGGIVIQQQLDYDLIQEYHLNITVQDLGYHPLSSVA 3318

Query: 881  QLSVRL 886
             L++ L
Sbjct: 3319 MLTIIL 3324



 Score =  292 bits (716), Expect = 1e-76
 Identities = 257/874 (29%), Positives = 414/874 (47%), Gaps = 56/874 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD-T 69
            I+V+D ND++P F    +  S+ E A + T V  L A D+DIG+NAE+ +T+   T D T
Sbjct: 1141 IHVIDENDNAPQFTNSTFTFSIPENAPADTFVGKLTAVDRDIGRNAELSFTLSSQTQDFT 1200

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            ++  +            + + ++   + A     SL R  +A   +L++AT   + +  R
Sbjct: 1201 IDTRNGFIKTLRPFDR-EALVKVSRNAEASGEDGSL-RGSMAGNYMLLEATVSDNGI-PR 1257

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            L     + V + D NDN P+F    Y V++ E  S  +   I  +   DAD G N  + Y
Sbjct: 1258 LQDKVKVKVIVTDVNDNAPEFLRAPYHVTISEGAS--EGTHITHVFTQDADEGLNGDVYY 1315

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG--SPSRSNTTQLLINI 247
            ++  GN   QF++DS +G +SL + LD E    + L++ A+D     P  SN + + I +
Sbjct: 1316 SLAKGNEAGQFNLDSATGQLSLGRRLDRESQEIHHLIVVAKDAALKHPLSSNAS-ITIVV 1374

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
             D NDNAP F  S  + SV E  P G  ++R +A DAD+GVN+++ ++++     GN   
Sbjct: 1375 LDENDNAPEFTQSSSEVSVLETSPTGTELMRFRASDADQGVNSQVVFSIS----AGNRRD 1430

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
               ID  +G +Y    LD E    Y L +TA+D G P  S T                F 
Sbjct: 1431 TFHIDSITGSLYLHKPLDYEDITSYTLNITASDCGTPSLSTTVLYNVLVVDDNDNPPIFP 1490

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGN---TRGR-FSITSQNGRG 421
                  ++ E  P  TP+VT+TA D D   + ++ Y I+       +GR F I ++   G
Sbjct: 1491 STAIVRQIKEGIPLKTPIVTVTADDPDSGLNGKVSYAISKQEPQLPQGRHFGINTET--G 1548

Query: 422  LITVAQPLDFKQERRYVLTVSATDSGGRSD-----TAMVQINITDANNYAPVF--ENAPY 474
            +I   + +D +    + LTV ATD    S+       +V + + D N+ APVF   NA  
Sbjct: 1549 VIHTLREIDRESIDTFRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAPVFVSMNAAI 1608

Query: 475  TASVFEDAP-IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
                F  +    T V+ V A D+D   N  +TY        E V+   + F +   TG I
Sbjct: 1609 LPPKFSTSKGSSTAVMQVHAKDADSSSNGLVTY--------EIVSGPQELFKLQRNTGII 1660

Query: 534  TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV-----DVNDNEPVFKQQ-LYT 587
            T       +    Y LT+ + D  V S   +++V I+++         + P F+Q+   +
Sbjct: 1661 TFTPGPQFKQEVRYQLTLKSTDEAVQSERRSSEVYITIITPGSGGSESSVPQFEQRSKLS 1720

Query: 588  ANIMEDALVGTSVSQVGA--TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645
             ++ E+  +GTS+  V A    A++            + + +  F ID   G++ T   L
Sbjct: 1721 GSVYENEPIGTSILTVTAHLASAEIEYFVTNVTATGSRGQVDRLFDIDAKLGILSTAAEL 1780

Query: 646  DRES-VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
            DRE+    ++++  AI  G  P++S   V + + D NDSPP F      + +SE+  IG 
Sbjct: 1781 DREAGPEEYEVEVYAIALGGQPRTSRTKVRVTVLDKNDSPPQFLDTPFVYNVSEDLQIGH 1840

Query: 705  TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764
            TI  +RAHDPD      V + +  G D   F LE   G    +L+    LD E+ + KYE
Sbjct: 1841 TISTLRAHDPD--TLGSVTFLLMDGHD-GKFLLEPSTG----KLILNDTLDRET-KSKYE 1892

Query: 765  LVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV- 823
            L IR +    + +    I V+D NDN P+ +D    F+  ++       G++ A DAD+ 
Sbjct: 1893 LRIRVSDGVQYTEAYATIQVSDTNDNPPLFEDTVYSFDIPENAQRGYQVGQIVARDADLG 1952

Query: 824  -TDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
               +L Y ++S    ++  LN  TG +TL+ +L+
Sbjct: 1953 QNAQLSYGVVSDWANDVFSLNPQTGMLTLTARLD 1986



 Score =  287 bits (703), Expect = 4e-75
 Identities = 244/842 (28%), Positives = 396/842 (47%), Gaps = 106/842 (12%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I VLD ND++P F     E SV E + +GT ++  +A+D D G N++V ++I        
Sbjct: 1372 IVVLDENDNAPEFTQSSSEVSVLETSPTGTELMRFRASDADQGVNSQVVFSISAGNR--- 1428

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                            +D F ID  +G+L     LD E +  YT+ + A+D  +P    L
Sbjct: 1429 ----------------RDTFHIDSITGSLYLHKPLDYEDITSYTLNITASDCGTP---SL 1469

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S+T   +V ++DDNDN P F        + E I +   P++  + A D D G N  + YA
Sbjct: 1470 STTVLYNVLVVDDNDNPPIFPSTAIVRQIKEGIPLK-TPIVT-VTADDPDSGLNGKVSYA 1527

Query: 191  IIGGNTQM----QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLI 245
            I     Q+     F I++ +G +  ++ +D E + ++RL + A D   PS R  +T+ L+
Sbjct: 1528 ISKQEPQLPQGRHFGINTETGVIHTLREIDRESIDTFRLTVVATDRAQPSERQLSTEKLV 1587

Query: 246  NI--RDVNDNAPRFYT---SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
             +   D+NDNAP F +   ++     S +     ++++V A DAD   N  +TY +    
Sbjct: 1588 TVIVEDINDNAPVFVSMNAAILPPKFSTSKGSSTAVMQVHAKDADSSSNGLVTYEIV--- 1644

Query: 301  YTGNVDLPITIDPRSGWV-YTSGQLDRETQAKYQLLVTATDGG-DPPRSATATXXXXXXX 358
             +G  +L   +   +G + +T G   ++ + +YQL + +TD      R ++         
Sbjct: 1645 -SGPQEL-FKLQRNTGIITFTPGPQFKQ-EVRYQLTLKSTDEAVQSERRSSEVYITIITP 1701

Query: 359  XXXXXXXFMPGQYEVE------LAEDEPPGTPVVTLTATDADEDNRLHY-EITGGNTRGR 411
                    +P Q+E        + E+EP GT ++T+TA  A  +       +T   +RG+
Sbjct: 1702 GSGGSESSVP-QFEQRSKLSGSVYENEPIGTSILTVTAHLASAEIEYFVTNVTATGSRGQ 1760

Query: 412  ----FSITSQNGRGLITVAQPLDFKQ-ERRYVLTVSATDSGGRSDTAMVQINIT--DANN 464
                F I ++   G+++ A  LD +     Y + V A   GG+  T+  ++ +T  D N+
Sbjct: 1761 VDRLFDIDAK--LGILSTAAELDREAGPEEYEVEVYAIALGGQPRTSRTKVRVTVLDKND 1818

Query: 465  YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524
              P F + P+  +V ED  IG T+  + A D D      +T+ L           HD +F
Sbjct: 1819 SPPQFLDTPFVYNVSEDLQIGHTISTLRAHDPDT--LGSVTFLLMDG--------HDGKF 1868

Query: 525  VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584
            ++ P TG +  N  LDRET S Y L +   DG   + +  T   I V D NDN P+F+  
Sbjct: 1869 LLEPSTGKLILNDTLDRETKSKYELRIRVSDGVQYTEAYAT---IQVSDTNDNPPLFEDT 1925

Query: 585  LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA 644
            +Y+ +I E+A  G  V Q+ A DAD+G N ++ Y +   D     F ++P +G++     
Sbjct: 1926 VYSFDIPENAQRGYQVGQIVARDADLGQNAQLSYGV-VSDWANDVFSLNPQTGMLTLTAR 1984

Query: 645  LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
            LD E V  + L   A D G P  S+T+ V+  + D+ND+ P+F+    +  + EN PI T
Sbjct: 1985 LDYEEVQHYILIVQAQDNGQPSLSTTITVYCNVLDLNDNAPIFDPMSYSSEVFENVPIAT 2044

Query: 705  TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE------TRQGSDK------------- 745
             +  + A D D G N ++ YSI  GD  + F ++      TR+  D+             
Sbjct: 2045 EVVTVSAKDIDSGNNGLIEYSITAGDVDSEFGIDSNGTIRTRRNLDREHRSTYTLTVTAR 2104

Query: 746  ---------AEL-VTMVDLDYESPRK----KYELVIRAASPPLWNDVRVEILVTDVNDNA 791
                     +EL  T + L Y SPRK    + E +       L + V+V IL+ DVND  
Sbjct: 2105 DCADEFASFSELEETQLKLKYRSPRKYQQTRQEFLAHQKQQRLSSTVKVTILIKDVNDEV 2164

Query: 792  PV 793
            PV
Sbjct: 2165 PV 2166



 Score =  285 bits (699), Expect = 1e-74
 Identities = 273/932 (29%), Positives = 411/932 (44%), Gaps = 88/932 (9%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            I  +I VLD ND+SP F       S  E A+SGT +L   ATD D+G+N  V    E+V 
Sbjct: 140  IEVRIKVLDVNDNSPEFPEPSIAISFSESATSGTRLLLDAATDADVGENG-VTDQYEIVA 198

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
             +     D             D   +      L T  +LDRE    Y + + A D  SP 
Sbjct: 199  GNV----DNKFRLVTTANPSGDTSYLH-----LETTGNLDRESRGSYQLNISARDGGSPP 249

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
                     ++V I+D NDN P F    Y VS++E  ++   PV+  + A+D D+G NS 
Sbjct: 250  R---FGYLQVNVTILDVNDNPPIFDHSDYNVSLNE-TALPGTPVVT-VMASDNDLGDNSK 304

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQ---------VRSYRLVIRAQDGGSPSR 237
            I Y +    T+ QF+++  +G +S  + ++  Q          +S    + A+D GSP +
Sbjct: 305  ITYYL--AETEHQFTVNPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFARDHGSPRQ 362

Query: 238  SNTTQLLINIRDVNDNAPRFYTSLFQE-----SVSENVPIGYSIVRVQAYDADEGVNAEL 292
               T + +N+ D ND+ P      F +     +V EN   G  +  V   D+D G+N   
Sbjct: 363  DGRTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDENAVNGTVVAAVAVKDSDSGLNGRT 422

Query: 293  TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352
            +  +   +  G+  L    D     V  +G LDRE   KY L V A D G P R+ TA  
Sbjct: 423  SVRIVSGNELGHFRLEEAADLHI--VRVNGVLDREEIGKYNLTVVAMDQGTPARTTTAHL 480

Query: 353  XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRG 410
                         F   +Y   L+E  P G+ V ++TATD D   + ++HY+I  GN   
Sbjct: 481  IIDVNDVNDHEPVFEKSEYSAVLSELAPTGSFVASITATDEDTGVNAQVHYDILSGNELK 540

Query: 411  RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYAPV 468
             FS+      GLI    PLD +      L++SA D G     A  Q+   I D N+ AP 
Sbjct: 541  WFSMDPLT--GLIVTTGPLDREIRDTVELSISARDGGPNPKFAYTQLKVIILDENDEAPQ 598

Query: 469  FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528
            F       ++ EDAP  T V +++ATD D G N  +T++L+  +       +  QF ++ 
Sbjct: 599  FSQREQNVTLGEDAPPQTIVALMTATDHDQGTNGSVTFALAPSVER----LYPLQFALDA 654

Query: 529  QTGAITTNKLLDRETMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVF--KQQL 585
             TG +TT + LDRE MS Y ++V ARD G P+  S T  V ++V DVNDN+P F  +  +
Sbjct: 655  LTGQLTTRRPLDREKMSQYEISVIARDQGAPTPQSATATVWLNVADVNDNDPQFYPRHYI 714

Query: 586  YT-ANIMEDALVGTSVSQ------VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638
            Y+ A+  +D  +   V +      V A+D D G N  I Y L+     EG F +D  SG 
Sbjct: 715  YSLADDDDDIKLKKEVEKERILLHVTASDKDDGDNALIEYRLE--SGGEGLFQLDARSGA 772

Query: 639  I--RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC--LTF 694
            I  R +          + L   A D G        IV I ++   +     ++      F
Sbjct: 773  ISLRGDAPASMHWKPHYKLLVSARDAGQRRSQQDAIVEIVLKSKLEMLECGQAQAGGYEF 832

Query: 695  YISE------NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAEL 748
             + E      NS     +G ++    +   N+ + Y I  GD + +F ++TR G     +
Sbjct: 833  QMVEDHEQQRNSQPNREVGIVQVKSTNGKANSHIEYDIIQGDRAQNFRIDTRSG----RI 888

Query: 749  VTMVDLDYESPRKKYELVI---------RAASPPLWNDVRVEILVTDVNDNAPVM---KD 796
             T   LD E  +  Y L I          AAS   +    V I + D+NDNAPV    ++
Sbjct: 889  TTARPLDREE-QANYRLTILASSSSSSSAAASSVSYGQCIVNIAIIDLNDNAPVFALDRE 947

Query: 797  FQIIFNNYKDCFPVGP---FGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSP 853
             +   +  ++   VG      RV   DA V  ++ Y  L+ N      +   TG + L  
Sbjct: 948  SEPTISLPENA-AVGQEIYLSRVRDRDAGVNSRISYS-LTNNPNQQFRIGPVTGVLYLQR 1005

Query: 854  QLNTNVPKLATMEVSVTD-GVNEIKAMMQLSV 884
             +      L  +E+  TD G   + + + LSV
Sbjct: 1006 PIRAEPGSLIHVELMATDAGSPPLSSKLSLSV 1037



 Score =  283 bits (695), Expect = 4e-74
 Identities = 214/694 (30%), Positives = 332/694 (47%), Gaps = 64/694 (9%)

Query: 90  FRIDGRSGALLTRASLDREKVA-RYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           F +D  +G + T   LDRE +   Y ++V ++    P+         + + ++D NDN P
Sbjct: 103 FTLDPVTGEVKTNVVLDREGMRDHYDLVVLSSQPTYPIE--------VRIKVLDVNDNSP 154

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI-RYAIIGGNTQMQFSIDSL-- 205
           +F E +  +S  E  S T    +    ATDADVG N    +Y I+ GN   +F + +   
Sbjct: 155 EFPEPSIAISFSE--SATSGTRLLLDAATDADVGENGVTDQYEIVAGNVDNKFRLVTTAN 212

Query: 206 -SGDVSLVK-----TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259
            SGD S +       LD E   SY+L I A+DGGSP R    Q+ + I DVNDN P F  
Sbjct: 213 PSGDTSYLHLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDH 272

Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319
           S +  S++E    G  +V V A D D G N+++TY      Y    +   T++P +G + 
Sbjct: 273 SDYNVSLNETALPGTPVVTVMASDNDLGDNSKITY------YLAETEHQFTVNPETGVIS 326

Query: 320 TSGQLD--RETQAKYQ-------LLVTATDGGDPPRS----ATATXXXXXXXXXXXXXXF 366
           T+ +++  ++T  K           V A D G P +      T                F
Sbjct: 327 TTERVNCPQQTNVKSSASQKSCVFTVFARDHGSPRQDGRTYVTVNLLDTNDHDPIISFRF 386

Query: 367 MP-GQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLI 423
            P G     + E+   GT V  +   D+D   + R    I  GN  G F +       ++
Sbjct: 387 FPDGGKVATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRIVSGNELGHFRLEEAADLHIV 446

Query: 424 TVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
            V   LD ++  +Y LTV A D G   R+ TA + I++ D N++ PVFE + Y+A + E 
Sbjct: 447 RVNGVLDREEIGKYNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEPVFEKSEYSAVLSEL 506

Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
           AP G+ V  ++ATD D G+NAQ+ Y + S   NE      + F ++P TG I T   LDR
Sbjct: 507 APTGSFVASITATDEDTGVNAQVHYDILS--GNEL-----KWFSMDPLTGLIVTTGPLDR 559

Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
           E      L+++ARDGG       T +++ ++D ND  P F Q+     + EDA   T V+
Sbjct: 560 EIRDTVELSISARDGGPNPKFAYTQLKVIILDENDEAPQFSQREQNVTLGEDAPPQTIVA 619

Query: 602 QVGATDADVGLNGRIHYELDPKDRE--EGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
            + ATD D G NG + + L P         F +D  +G + T + LDRE ++ +++  +A
Sbjct: 620 LMTATDHDQGTNGSVTFALAPSVERLYPLQFALDALTGQLTTRRPLDREKMSQYEISVIA 679

Query: 660 IDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR-------- 710
            D G P PQS+T  V + + D+ND+ P F      + ++++        E+         
Sbjct: 680 RDQGAPTPQSATATVWLNVADVNDNDPQFYPRHYIYSLADDDDDIKLKKEVEKERILLHV 739

Query: 711 -AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
            A D D+G NA++ Y ++ G +   F L+ R G+
Sbjct: 740 TASDKDDGDNALIEYRLESGGE-GLFQLDARSGA 772



 Score =  268 bits (657), Expect = 1e-69
 Identities = 251/879 (28%), Positives = 401/879 (45%), Gaps = 90/879 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI-ELVTADT 69
            + +LD ND+ P+F+   Y  S+ E A  GT V+T+ A+D D+G N+++ Y + E     T
Sbjct: 258  VTILDVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDNDLGDNSKITYYLAETEHQFT 317

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            +NPE             Q     + +S A         +K   +TV   A D  SP  D 
Sbjct: 318  VNPETGVISTTERVNCPQQT---NVKSSA--------SQKSCVFTVF--ARDHGSPRQD- 363

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTY-----TVSVDEDISVTDNPVIAKIKATDADVGAN 184
                  + VN++D ND+ P  S + +       +VDE+    +  V+A +   D+D G N
Sbjct: 364  --GRTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDEN--AVNGTVVAAVAVKDSDSGLN 419

Query: 185  SAIRYAIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRSNTT 241
                  I+ GN    F ++  + D+ +V+    LD E++  Y L + A D G+P+R+ T 
Sbjct: 420  GRTSVRIVSGNELGHFRLEE-AADLHIVRVNGVLDREEIGKYNLTVVAMDQGTPARTTTA 478

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
             L+I++ DVND+ P F  S +   +SE  P G  +  + A D D GVNA++ Y +     
Sbjct: 479  HLIIDVNDVNDHEPVFEKSEYSAVLSELAPTGSFVASITATDEDTGVNAQVHYDIL---- 534

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
            +GN     ++DP +G + T+G LDRE +   +L ++A DGG  P+ A             
Sbjct: 535  SGNELKWFSMDPLTGLIVTTGPLDREIRDTVELSISARDGGPNPKFAYTQLKVIILDEND 594

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRG---RFSITS 416
                F   +  V L ED PP T V  +TATD D+  +  + + +     R    +F++ +
Sbjct: 595  EAPQFSQREQNVTLGEDAPPQTIVALMTATDHDQGTNGSVTFALAPSVERLYPLQFALDA 654

Query: 417  QNGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAP 473
              G+  +T  +PLD ++  +Y ++V A D G    +S TA V +N+ D N+  P F    
Sbjct: 655  LTGQ--LTTRRPLDREKMSQYEISVIARDQGAPTPQSATATVWLNVADVNDNDPQFYPRH 712

Query: 474  YTASVFED---------APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524
            Y  S+ +D               +L V+A+D D G NA I Y L S    E +      F
Sbjct: 713  YIYSLADDDDDIKLKKEVEKERILLHVTASDKDDGDNALIEYRLES--GGEGL------F 764

Query: 525  VINPQTGAITT--NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582
             ++ ++GAI+   +          Y L V+ARD G         VEI +    +     +
Sbjct: 765  QLDARSGAISLRGDAPASMHWKPHYKLLVSARDAGQRRSQQDAIVEIVLKSKLEMLECGQ 824

Query: 583  QQL--YTANIMED------ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634
             Q   Y   ++ED      +     V  V     +   N  I Y++   DR + +F ID 
Sbjct: 825  AQAGGYEFQMVEDHEQQRNSQPNREVGIVQVKSTNGKANSHIEYDIIQGDRAQ-NFRIDT 883

Query: 635  ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST------VIVHIKIEDINDSPPVFE 688
             SG I T + LDRE  A + L  +A    +   +++       IV+I I D+ND+ PVF 
Sbjct: 884  RSGRITTARPLDREEQANYRLTILASSSSSSSAAASSVSYGQCIVNIAIIDLNDNAPVFA 943

Query: 689  SDCL---TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745
             D     T  + EN+ +G  I   R  D D G N+ + YS+     +N+ + + R G   
Sbjct: 944  LDRESEPTISLPENAAVGQEIYLSRVRDRDAGVNSRISYSL-----TNNPNQQFRIGPVT 998

Query: 746  AELVTMVDLDYESPRKKY-ELVIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN 803
              L     +  E     + EL+   A SPPL + + + +L+ DVND+ PV  D      +
Sbjct: 999  GVLYLQRPIRAEPGSLIHVELMATDAGSPPLSSKLSLSVLIADVNDHTPVF-DHTSYETS 1057

Query: 804  YKDCFPVGP-FGRVPAYDADVTD--KLQYRILSGNNANL 839
              +   V   F  + A D D+ D  ++ Y I+ GN   +
Sbjct: 1058 LPETTKVNTRFFALAATDIDLGDNGRISYEIIEGNTERM 1096



 Score =  214 bits (522), Expect = 3e-53
 Identities = 163/514 (31%), Positives = 253/514 (49%), Gaps = 51/514 (9%)

Query: 310 TIDPRSGWVYTSGQLDRE-TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
           T+DP +G V T+  LDRE  +  Y L+V ++    P                     F  
Sbjct: 104 TLDPVTGEVKTNVVLDREGMRDHYDLVVLSSQPTYP-----IEVRIKVLDVNDNSPEFPE 158

Query: 369 GQYEVELAEDEPPGTPVVTLTATDADE-DNRL--HYEITGGNTRGRFS-ITSQNGRG--- 421
               +  +E    GT ++   ATDAD  +N +   YEI  GN   +F  +T+ N  G   
Sbjct: 159 PSIAISFSESATSGTRLLLDAATDADVGENGVTDQYEIVAGNVDNKFRLVTTANPSGDTS 218

Query: 422 --LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTAS 477
              +     LD +    Y L +SA D G       +Q+N+T  D N+  P+F+++ Y  S
Sbjct: 219 YLHLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVS 278

Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
           + E A  GT V+ V A+D+D+G N++ITY L         A  + QF +NP+TG I+T +
Sbjct: 279 LNETALPGTPVVTVMASDNDLGDNSKITYYL---------AETEHQFTVNPETGVISTTE 329

Query: 538 LLD---------RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY-- 586
            ++           +    + TV ARD G P     T V ++++D ND++P+   + +  
Sbjct: 330 RVNCPQQTNVKSSASQKSCVFTVFARDHGSPRQDGRTYVTVNLLDTNDHDPIISFRFFPD 389

Query: 587 ---TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG--VIRT 641
               A + E+A+ GT V+ V   D+D GLNGR    +     E G F ++ A+   ++R 
Sbjct: 390 GGKVATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRI-VSGNELGHFRLEEAADLHIVRV 448

Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701
           N  LDRE +  ++L  VA+D GTP +++T  + I + D+ND  PVFE    +  +SE +P
Sbjct: 449 NGVLDREEIGKYNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEPVFEKSEYSAVLSELAP 508

Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761
            G+ +  I A D D G NA VHY I  G++   FS++   G     +VT   LD E  R 
Sbjct: 509 TGSFVASITATDEDTGVNAQVHYDILSGNELKWFSMDPLTGL----IVTTGPLDREI-RD 563

Query: 762 KYELVI--RAASP-PLWNDVRVEILVTDVNDNAP 792
             EL I  R   P P +   ++++++ D ND AP
Sbjct: 564 TVELSISARDGGPNPKFAYTQLKVIILDENDEAP 597



 Score =  196 bits (477), Expect = 1e-47
 Identities = 142/415 (34%), Positives = 205/415 (49%), Gaps = 16/415 (3%)

Query: 450  SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509
            S T  V I I D N+  PVF +A  TA + E+  I T V+ V A D+D G N  I Y L 
Sbjct: 2148 SSTVKVTILIKDVNDEVPVFISANETA-IMENVAINTVVIAVKAVDNDEGRNGYIDY-LM 2205

Query: 510  SEISNEAVAHHDQ-QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568
             E  +E +   D   F +NP  G +     LDRE  S YLL +TARD G P  S  + + 
Sbjct: 2206 KEARDEDMGQSDPLPFSLNPTDGQLRVVDALDRELRSSYLLNITARDRGEPPQSTESQLL 2265

Query: 569  ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG 628
            I ++D NDN PVF  + Y+A++ E+A +G  V QV ATD D G NGRI Y +   D+   
Sbjct: 2266 IRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGRIRYSIVLGDQNH- 2324

Query: 629  SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVF 687
             F I   +GV+R  K L+ E ++ + L   A D     P   T  + I I DIND+ P F
Sbjct: 2325 DFSISEDTGVVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTINILDINDNRPTF 2384

Query: 688  ESDCLTFYISENS--PIGTTIGEIRAHDPDEGP-NAVVHYSIKGGDDSNSFSLETRQGSD 744
                    + EN+  P G  +  + A+D D  P N+ V Y +K G DS+ F +    G  
Sbjct: 2385 LDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKEG-DSDLFRINASSGD- 2442

Query: 745  KAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY 804
               L+  +D + +S      + +   SPPL     V + V D+NDN PV  + Q      
Sbjct: 2443 -IALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVF-ELQSYHATV 2500

Query: 805  KDCFPVGPFGRVP-AYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
            ++  P G     P A D D  +  KL++ +L G + +   ++  TG ++ +  L+
Sbjct: 2501 RENLPSGTHVLTPRATDKDEGLNAKLRFNLL-GEHMHRFHIDSETGEISTATTLD 2554



 Score =  151 bits (366), Expect = 3e-34
 Identities = 131/460 (28%), Positives = 204/460 (44%), Gaps = 34/460 (7%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT-YSL-SSEI 512
           V+I + D N+ +P F       S  E A  GT +L+ +ATD+DVG N     Y + +  +
Sbjct: 142 VRIKVLDVNDNSPEFPEPSIAISFSESATSGTRLLLDAATDADVGENGVTDQYEIVAGNV 201

Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572
            N+           +     + T   LDRE+   Y L ++ARDGG P       V ++++
Sbjct: 202 DNKFRLVTTANPSGDTSYLHLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTIL 261

Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632
           DVNDN P+F    Y  ++ E AL GT V  V A+D D+G N +I Y L   + +   F +
Sbjct: 262 DVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDNDLGDNSKITYYLAETEHQ---FTV 318

Query: 633 DPASGVIRTNKALD-------RESVATHD--LKAVAIDGGTPPQSSTVIVHIKIEDINDS 683
           +P +GVI T + ++       + S +         A D G+P Q     V + + D ND 
Sbjct: 319 NPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFARDHGSPRQDGRTYVTVNLLDTNDH 378

Query: 684 PPV-----FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738
            P+     F        + EN+  GT +  +   D D G N      I  G++   F LE
Sbjct: 379 DPIISFRFFPDGGKVATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRIVSGNELGHFRLE 438

Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMK 795
             + +D   +     LD E   K Y L + A    +P       + I V DVND+ PV +
Sbjct: 439 --EAADLHIVRVNGVLDREEIGK-YNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEPVFE 495

Query: 796 --DFQIIFNNYKDCFPVGPF-GRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMT 850
             ++  + +   +  P G F   + A D D  V  ++ Y ILSGN      ++  TG + 
Sbjct: 496 KSEYSAVLS---ELAPTGSFVASITATDEDTGVNAQVHYDILSGNELKWFSMDPLTGLIV 552

Query: 851 LSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITE 889
            +  L+  +     + +S  D G N   A  QL V ++ E
Sbjct: 553 TTGPLDREIRDTVELSISARDGGPNPKFAYTQLKVIILDE 592



 Score = 97.1 bits (231), Expect = 6e-18
 Identities = 83/280 (29%), Positives = 123/280 (43%), Gaps = 24/280 (8%)

Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
           G T   +    +  Y  +   RE   F +DP +G ++TN  LDRE +  H    V     
Sbjct: 80  GTTVGFIPTKPKFSYRFNEPPRE---FTLDPVTGEVKTNVVLDREGMRDHYDLVVLSSQP 136

Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV- 722
           T P    + V IK+ D+ND+ P F    +    SE++  GT +    A D D G N V  
Sbjct: 137 TYP----IEVRIKVLDVNDNSPEFPEPSIAISFSESATSGTRLLLDAATDADVGENGVTD 192

Query: 723 HYSIKGGDDSNSFSLETRQG----SDKAELVTMVDLDYESPRKKYELVIRA---ASPPLW 775
            Y I  G+  N F L T       +    L T  +LD ES R  Y+L I A    SPP +
Sbjct: 193 QYEIVAGNVDNKFRLVTTANPSGDTSYLHLETTGNLDRES-RGSYQLNISARDGGSPPRF 251

Query: 776 NDVRVEILVTDVNDNAPVM--KDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILS 833
             ++V + + DVNDN P+    D+ +  N  +   P  P   V A D D+ D  +     
Sbjct: 252 GYLQVNVTILDVNDNPPIFDHSDYNVSLN--ETALPGTPVVTVMASDNDLGDNSKITYYL 309

Query: 834 GNNANLILLNETTGSMTLSPQLN----TNVPKLATMEVSV 869
               +   +N  TG ++ + ++N    TNV   A+ +  V
Sbjct: 310 AETEHQFTVNPETGVISTTERVNCPQQTNVKSSASQKSCV 349



 Score = 91.9 bits (218), Expect = 2e-16
 Identities = 98/332 (29%), Positives = 138/332 (41%), Gaps = 55/332 (16%)

Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYT 1099
            +S+ C C  GF G  CE++    SC  +     C  G  CV+ + G      C+      
Sbjct: 4074 SSYFCLCRPGFRGNQCESV--SDSCRPNP----CLHGGLCVSLKPG----YKCNCTPGRY 4123

Query: 1100 TAVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYN--GRYNERHDFLAL 1157
               CE  +  F   S++TFP L       + + FAT   + LLLYN   +   R DFLA+
Sbjct: 4124 GRHCERFSYGFQPLSYMTFPALDVTTN-DISIVFATTKPNSLLLYNYGMQSGGRSDFLAI 4182

Query: 1158 ELVSSEAGRGGGPGLRFSFSLGGGKSEIT--VEG-NVGDGSWHTVEIEYFNRTITMILDD 1214
            ELV   A           FS GG ++ I+  + G N+ DG WH V      R ++     
Sbjct: 4183 ELVHGRA----------YFSSGGARTAISTVIAGRNLADGGWHKVTATRNGRVMS----- 4227

Query: 1215 CDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLT---GPLQIGGL---- 1267
                LS+A  AD G      +   + LP       +       L     PL IGGL    
Sbjct: 4228 ----LSVAKCADSG------DVCTECLPGDSSCYADEVGPVGTLNFNKQPLMIGGLSSAD 4277

Query: 1268 PNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSA----PCY 1323
            P +    QV + D VGC+   +I  + ++L+  +   G LAGC   R  C  A     C 
Sbjct: 4278 PILERPGQVHSDDLVGCLHSVHIGGRALNLSLPLQQKGILAGC--NRQACQPALAAERCG 4335

Query: 1324 NGA-ECSDLWDTYICDCKEGHTGKDCADSTGP 1354
              A +C D W + +C C       DC+DS  P
Sbjct: 4336 GFAGQCIDRWSSSLCQCGGHLQSPDCSDSLEP 4367



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 64/281 (22%), Positives = 109/281 (38%), Gaps = 40/281 (14%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC----------ADSTGPPWRFG 1359
            C      C   PC +G  C  L   Y C+C  G  G+ C          +  T P     
Sbjct: 4089 CESVSDSCRPNPCLHGGLCVSLKPGYKCNCTPGRYGRHCERFSYGFQPLSYMTFPALDVT 4148

Query: 1360 GDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMSIQLKSGLLHYSYNGETMYLPMA--- 1416
             + +       +P  L   N   +++  R  F ++I+L  G  ++S  G    +      
Sbjct: 4149 TNDISIVFATTKPNSLLLYN-YGMQSGGRSDF-LAIELVHGRAYFSSGGARTAISTVIAG 4206

Query: 1417 -TLSDGAWHRIEIKWLGTDISVTV----DYG-LRTVLMPMLANKIQGQY--IGKI----- 1463
              L+DG WH++     G  +S++V    D G + T  +P  ++    +   +G +     
Sbjct: 4207 RNLADGGWHKVTATRNGRVMSLSVAKCADSGDVCTECLPGDSSCYADEVGPVGTLNFNKQ 4266

Query: 1464 --LIGGLDTTAGLLASDVGFFE----GCIQDVRIGTAQSLLNRPTVRENVRDGCQSRADC 1517
              +IGGL +   +L            GC+  V IG     L+ P  ++ +  GC  +A C
Sbjct: 4267 PLMIGGLSSADPILERPGQVHSDDLVGCLHSVHIGGRALNLSLPLQQKGILAGCNRQA-C 4325

Query: 1518 MLSI----CPPYS-KCVTSWDSSTCTCEAGRVGPQCVSACE 1553
              ++    C  ++ +C+  W SS C C      P C  + E
Sbjct: 4326 QPALAAERCGGFAGQCIDRWSSSLCQCGGHLQSPDCSDSLE 4366



 Score = 36.7 bits (81), Expect = 9.2
 Identities = 30/81 (37%), Positives = 34/81 (41%), Gaps = 12/81 (14%)

Query: 1508 RDG--CQS-RAD-CMLSICPPYSKCVTSWDSST--CTCEAGRVGPQCVS---ACELGPC- 1557
            RDG  C+  R+D C    C     C  S D S+  C C  G  G QC S   +C   PC 
Sbjct: 4043 RDGKHCEKERSDVCYSKPCRNGGSCQRSPDGSSYFCLCRPGFRGNQCESVSDSCRPNPCL 4102

Query: 1558 GAARCVPDQTPKGYSCACEPG 1578
                CV      GY C C PG
Sbjct: 4103 HGGLCV--SLKPGYKCNCTPG 4121



 Score = 36.7 bits (81), Expect = 9.2
 Identities = 23/58 (39%), Positives = 28/58 (48%), Gaps = 7/58 (12%)

Query: 1310 CPEKRSR-CSSAPCYNGAECSDLWD--TYICDCKEGHTGKDC---ADSTGP-PWRFGG 1360
            C ++RS  C S PC NG  C    D  +Y C C+ G  G  C   +DS  P P   GG
Sbjct: 4048 CEKERSDVCYSKPCRNGGSCQRSPDGSSYFCLCRPGFRGNQCESVSDSCRPNPCLHGG 4105


>UniRef50_UPI0000E49AEF Cluster: PREDICTED: similar to Fat4; n=5;
            Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
            Fat4 - Strongylocentrotus purpuratus
          Length = 4601

 Score =  339 bits (834), Expect = 5e-91
 Identities = 256/801 (31%), Positives = 386/801 (48%), Gaps = 67/801 (8%)

Query: 11   INVLDCNDHSPVFEMQQ----YEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            + V D ND++PVF  +     Y  S+ E   +GT ++ +  TD D G NA V Y+I    
Sbjct: 936  VTVTDVNDNNPVFINRPIDNIYRGSINENDQTGTFIVQVSTTDADSGSNAAVTYSI---- 991

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
                               + +VF I+  SGA+     L       YT+ V+AT+    V
Sbjct: 992  ---------------ISGNINNVFTINPTSGAITNTQILGPNTPQTYTLSVRATNPTPGV 1036

Query: 127  SDRL-SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
            +    +ST+T+ + + D ND+ P+FS+  +TV ++E   V     + +I ATD D+    
Sbjct: 1037 APATGTSTSTVIITVNDVNDSPPRFSDDEFTVFINEAAQV--GTTVTRITATDEDIPEGD 1094

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
             + Y I  GNT   F I+ +SGDV+L++ LD E    + L IRA D G+P +S TT L +
Sbjct: 1095 RLTYIITAGNTGGHFQINPVSGDVTLLRQLDRELESQHNLTIRATDQGAPPQSATTTLKV 1154

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
             + D NDNAP++    + +S+ ENVP+   +++V A DAD+G NA+L++T+ + +     
Sbjct: 1155 IVLDFNDNAPQWSPQSYVDSILENVPLNTFVLQVVATDADQGTNADLSFTINNAN----- 1209

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT--ATXXXXXXXXXXXX 363
            ++P  ID + G + TSG L+RET  +Y  LVT  D G P ++    AT            
Sbjct: 1210 NVPFVIDDQ-GNIRTSGPLNRETVPQYNFLVTVLDNGSPQQAGNPPATVTINILDVNDEP 1268

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423
                   YE  ++ED    T V  +TATD D    L Y     +    FS  S    G I
Sbjct: 1269 PVLDRNSYEFTVSEDVNFNTFVGQVTATDPDLSGTLTYTFVPADP--DFSYIS----GTI 1322

Query: 424  TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
                 LD  Q++ Y +TV A+D    S +A V IN+ D NN AP F    Y  S+ ED+P
Sbjct: 1323 RTNTQLDANQQQVYQMTVFASDGVQNSQSAPVTINVLDVNNQAPSFGLGTYVKSLPEDSP 1382

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA--ITTNKLLDR 541
              T V+ ++ATD D G    I YS       E+++     F ++P TG   I+T   LDR
Sbjct: 1383 FQTLVVDLNATDPDNGNTGLIIYSF------ESLSRTQGPFTVDPYTGVVEISTTAGLDR 1436

Query: 542  ETMSGYLLTVTARD---GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            ET   Y + V A D    G P ++ T  V + V DVNDN P F+   Y  +I E+  +G+
Sbjct: 1437 ETQDEYTMIVIAVDQPASGQP-MTGTATVSVIVTDVNDNAPTFRDISYEESIFENHPLGS 1495

Query: 599  SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
            ++  V A D D+G+N  + Y +         F +D    +   +  LDRE    + L   
Sbjct: 1496 NILTVQADDPDLGVNAVVLYRI-ISGNNNNLFNVDGQGNINLGSTPLDREMQDQYFLIVQ 1554

Query: 659  AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY---ISENSPIGTTIGEIRAHDPD 715
            A +      ++ V V I I DIND  P+F+     +Y   +SENSP GT + ++ A D D
Sbjct: 1555 AYNSDLSVGTNEVPVIINILDINDVTPLFQQQ--NYYRPDLSENSPSGTPVLQVFAQDQD 1612

Query: 716  EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASP 772
                  V YS+ G  +  + + +T   S    +  +      S  + + + +RA   ASP
Sbjct: 1613 LDLAGDVQYSLIGNPNFLTINSDTGVISVNGPIADL------SGSRNFTMTVRATDQASP 1666

Query: 773  PLWNDVRVEILVTDVNDNAPV 793
             L     V + V D     P+
Sbjct: 1667 FLRGVATVTVTVVDDTVTIPI 1687



 Score =  331 bits (813), Expect = 2e-88
 Identities = 268/862 (31%), Positives = 415/862 (48%), Gaps = 88/862 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            ++VL+  D +PVF    Y+ ++ E    G+TV T+ ATD D      + Y   LV +D+ 
Sbjct: 719  VSVLNIQDTNPVFINTPYDVTIPETLPVGSTVQTITATDPDSNDGNIITYN--LVVSDS- 775

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKV---ARYTVLVKATDQASPVS 127
                            Q  F ID  +G +   + +DR+     A Y ++V A + +S   
Sbjct: 776  ----------------QGYFVIDQTTGIITVNSQMDRDNPVLPATYPLIVSAVETSS--G 817

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
                +  + +V +   ND  P F + +Y+ S+ E  SV     I  I   D D+  +S +
Sbjct: 818  GVSFAQVSFNVTVSPANDEPPMFDQNSYSASIPESASVNSQLPIT-ITVNDGDLITDSTV 876

Query: 188  RYAIIGGNT-QMQFSIDSLSG----DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
              ++  GN+   + S   + G    D+ + + LD+E  + Y L ++A DG      +   
Sbjct: 877  TVSLQNGNSVPFRVSPTQVVGSGTVDILITQPLDFENNQQYTLQLQAVDGDG---QDIAP 933

Query: 243  LLINIRDVNDNAPRFYT----SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
            L++ + DVNDN P F      ++++ S++EN   G  IV+V   DAD G NA +TY++  
Sbjct: 934  LMVTVTDVNDNNPVFINRPIDNIYRGSINENDQTGTFIVQVSTTDADSGSNAAVTYSII- 992

Query: 299  KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG--GDPPRSATATXXXXX 356
               +GN++   TI+P SG +  +  L   T   Y L V AT+   G  P + T+T     
Sbjct: 993  ---SGNINNVFTINPTSGAITNTQILGPNTPQTYTLSVRATNPTPGVAPATGTSTSTVII 1049

Query: 357  XXXXXXXX--XFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRF 412
                       F   ++ V + E    GT V  +TATD D  E +RL Y IT GNT G F
Sbjct: 1050 TVNDVNDSPPRFSDDEFTVFINEAAQVGTTVTRITATDEDIPEGDRLTYIITAGNTGGHF 1109

Query: 413  SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFE 470
             I   +G   +T+ + LD + E ++ LT+ ATD G   +S T  +++ + D N+ AP + 
Sbjct: 1110 QINPVSGD--VTLLRQLDRELESQHNLTIRATDQGAPPQSATTTLKVIVLDFNDNAPQWS 1167

Query: 471  NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
               Y  S+ E+ P+ T VL V ATD+D G NA +++++++         ++  FVI+ Q 
Sbjct: 1168 PQSYVDSILENVPLNTFVLQVVATDADQGTNADLSFTINNA--------NNVPFVIDDQ- 1218

Query: 531  GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT--TDVEISVVDVNDNEPVFKQQLYTA 588
            G I T+  L+RET+  Y   VT  D G P  +      V I+++DVND  PV  +  Y  
Sbjct: 1219 GNIRTSGPLNRETVPQYNFLVTVLDNGSPQQAGNPPATVTINILDVNDEPPVLDRNSYEF 1278

Query: 589  NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648
             + ED    T V QV ATD D  L+G + Y   P D  + S++    SG IRTN  LD  
Sbjct: 1279 TVSEDVNFNTFVGQVTATDPD--LSGTLTYTFVPAD-PDFSYI----SGTIRTNTQLDAN 1331

Query: 649  SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
                + +   A DG    QS+ V +++   D+N+  P F        + E+SP  T + +
Sbjct: 1332 QQQVYQMTVFASDGVQNSQSAPVTINVL--DVNNQAPSFGLGTYVKSLPEDSPFQTLVVD 1389

Query: 709  IRAHDPDEGPNAVVHYSIKG-GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
            + A DPD G   ++ YS +        F+++   G    E+ T   LD E+  +   +VI
Sbjct: 1390 LNATDPDNGNTGLIIYSFESLSRTQGPFTVDPYTGV--VEISTTAGLDRETQDEYTMIVI 1447

Query: 768  RAASP----PLWNDVRVEILVTDVNDNAPVMKDF---QIIFNNYKDCFPVGP-FGRVPAY 819
                P    P+     V ++VTDVNDNAP  +D    + IF N+    P+G     V A 
Sbjct: 1448 AVDQPASGQPMTGTATVSVIVTDVNDNAPTFRDISYEESIFENH----PLGSNILTVQAD 1503

Query: 820  DAD--VTDKLQYRILSGNNANL 839
            D D  V   + YRI+SGNN NL
Sbjct: 1504 DPDLGVNAVVLYRIISGNNNNL 1525



 Score =  293 bits (720), Expect = 3e-77
 Identities = 263/888 (29%), Positives = 406/888 (45%), Gaps = 81/888 (9%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ VLD ND++P +  Q Y  S+ E     T VL + ATD D G NA++ +TI    A+ 
Sbjct: 1153 KVIVLDFNDNAPQWSPQSYVDSILENVPLNTFVLQVVATDADQGTNADLSFTIN--NANN 1210

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            +                   F ID + G + T   L+RE V +Y  LV   D  SP    
Sbjct: 1211 V------------------PFVIDDQ-GNIRTSGPLNRETVPQYNFLVTVLDNGSP-QQA 1250

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             +  AT+ +NI+D ND  P     +Y  +V ED++   N  + ++ ATD D+  +  + Y
Sbjct: 1251 GNPPATVTINILDVNDEPPVLDRNSYEFTVSEDVNF--NTFVGQVTATDPDL--SGTLTY 1306

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
              +  +    +    +SG +     LD  Q + Y++ + A DG   S+S    + IN+ D
Sbjct: 1307 TFVPADPDFSY----ISGTIRTNTQLDANQQQVYQMTVFASDGVQNSQS--APVTINVLD 1360

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            VN+ AP F    + +S+ E+ P    +V + A D D G    + Y+      T     P 
Sbjct: 1361 VNNQAPSFGLGTYVKSLPEDSPFQTLVVDLNATDPDNGNTGLIIYSFESLSRTQG---PF 1417

Query: 310  TIDPRSGWV--YTSGQLDRETQAKYQLLVTATD--GGDPPRSATATXXXXXXXXXXXXXX 365
            T+DP +G V   T+  LDRETQ +Y ++V A D      P + TAT              
Sbjct: 1418 TVDPYTGVVEISTTAGLDRETQDEYTMIVIAVDQPASGQPMTGTATVSVIVTDVNDNAPT 1477

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLI 423
            F    YE  + E+ P G+ ++T+ A D D   +  + Y I  GN    F++   +G+G I
Sbjct: 1478 FRDISYEESIFENHPLGSNILTVQADDPDLGVNAVVLYRIISGNNNNLFNV---DGQGNI 1534

Query: 424  TV-AQPLDFKQERRYVLTVSA--TDSGGRSDTAMVQINITDANNYAPVFENAP-YTASVF 479
             + + PLD + + +Y L V A  +D    ++   V INI D N+  P+F+    Y   + 
Sbjct: 1535 NLGSTPLDREMQDQYFLIVQAYNSDLSVGTNEVPVIINILDINDVTPLFQQQNYYRPDLS 1594

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN-KL 538
            E++P GT VL V A D D+ +   + YSL   I N           IN  TG I+ N  +
Sbjct: 1595 ENSPSGTPVLQVFAQDQDLDLAGDVQYSL---IGN------PNFLTINSDTGVISVNGPI 1645

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
             D      + +TV A D   P L     V ++VVD     P+F    Y A ++E+    T
Sbjct: 1646 ADLSGSRNFTMTVRATDQASPFLRGVATVTVTVVDDTVTIPIFTLSRYPATVIENVNADT 1705

Query: 599  SVSQVGATDADVGLNGR---IHYELDPKDREE--GSFVIDPASGVIRTNKALDRESVATH 653
             V++V AT     LNG    I Y +DP         F ID  +G I T  A+DRE    +
Sbjct: 1706 PVTRVSAT-----LNGNPAGITYAIDPNASPAVLEIFKIDENTGHITTEGAIDREVEDFY 1760

Query: 654  DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES-DCLTFYISENSPIGTTIGEIRAH 712
                 A    +    ST  V + I D ND+PP F +       + EN+     +G  RA 
Sbjct: 1761 AFTVFAYHEDSVAPGST-SVWVNILDENDNPPEFITVPPSPVSVRENTGGNVPVGLFRAT 1819

Query: 713  DPDEGPNAVVHYSIKGGDDSNSFSL-ETRQGSDKAELVTMVDLDYESPRKKYELVIRA-- 769
            DPD G NA + +SI G   SN F++ +T  G     +V    LD E  +  Y+L + A  
Sbjct: 1820 DPDAGINAQMTFSISGA-GSNFFNVFQTANGG--GTIVVTSPLDRER-QDFYQLTVTATD 1875

Query: 770  -ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDK 826
              +P L +   + I VTDVNDN P+        +  ++ F   P   V   D D+  ++ 
Sbjct: 1876 GGNPSLSSSFPLNITVTDVNDNYPIWTRNVYEGSINENNFTSNPIITVMVNDLDLPSSNN 1935

Query: 827  LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN 874
             +Y I++G+   +  +N + G +T+S  L+    +   + + + D  N
Sbjct: 1936 FEYSIIAGDPMGMFEIN-SNGEITVSSLLDREQQETYQLTIELIDQTN 1982



 Score =  291 bits (715), Expect = 1e-76
 Identities = 243/799 (30%), Positives = 368/799 (46%), Gaps = 58/799 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            INVLD N+ +P F +  Y  S+ E +   T V+ L ATD D G    + Y+ E ++    
Sbjct: 1356 INVLDVNNQAPSFGLGTYVKSLPEDSPFQTLVVDLNATDPDNGNTGLIIYSFESLSR--- 1412

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGA--LLTRASLDREKVARYTVLVKATDQASPVSD 128
                            Q  F +D  +G   + T A LDRE    YT++V A DQ  P S 
Sbjct: 1413 ---------------TQGPFTVDPYTGVVEISTTAGLDRETQDEYTMIVIAVDQ--PASG 1455

Query: 129  R-LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
            + ++ TAT+ V + D NDN P F + +Y  S+ E+  +  N  I  ++A D D+G N+ +
Sbjct: 1456 QPMTGTATVSVIVTDVNDNAPTFRDISYEESIFENHPLGSN--ILTVQADDPDLGVNAVV 1513

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
             Y II GN    F++D   G+++L  T LD E    Y L+++A +      +N   ++IN
Sbjct: 1514 LYRIISGNNNNLFNVDG-QGNINLGSTPLDREMQDQYFLIVQAYNSDLSVGTNEVPVIIN 1572

Query: 247  IRDVNDNAPRFYT-SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
            I D+ND  P F   + ++  +SEN P G  +++V A D D  +  ++ Y++      GN 
Sbjct: 1573 ILDINDVTPLFQQQNYYRPDLSENSPSGTPVLQVFAQDQDLDLAGDVQYSLI-----GNP 1627

Query: 306  DLPITIDPRSGWVYTSGQL-DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
            +  +TI+  +G +  +G + D      + + V ATD   P     AT             
Sbjct: 1628 NF-LTINSDTGVISVNGPIADLSGSRNFTMTVRATDQASPFLRGVATVTVTVVDDTVTIP 1686

Query: 365  XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITS-QNGRGLI 423
             F   +Y   + E+    TPV  ++AT       + Y I    +     I       G I
Sbjct: 1687 IFTLSRYPATVIENVNADTPVTRVSATLNGNPAGITYAIDPNASPAVLEIFKIDENTGHI 1746

Query: 424  TVAQPLDFKQERRYVLTVSA--TDSGGRSDTAMVQINITDANNYAPVFENAPYT-ASVFE 480
            T    +D + E  Y  TV A   DS     T+ V +NI D N+  P F   P +  SV E
Sbjct: 1747 TTEGAIDREVEDFYAFTVFAYHEDSVAPGSTS-VWVNILDENDNPPEFITVPPSPVSVRE 1805

Query: 481  DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
            +      V +  ATD D GINAQ+T+S+S   SN         F      G I     LD
Sbjct: 1806 NTGGNVPVGLFRATDPDAGINAQMTFSISGAGSN-----FFNVFQTANGGGTIVVTSPLD 1860

Query: 541  RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
            RE    Y LTVTA DGG PSLS +  + I+V DVNDN P++ + +Y  +I E+      +
Sbjct: 1861 RERQDFYQLTVTATDGGNPSLSSSFPLNITVTDVNDNYPIWTRNVYEGSINENNFTSNPI 1920

Query: 601  SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
              V   D D+  +    Y +   D   G F I+ ++G I  +  LDRE   T+ L    I
Sbjct: 1921 ITVMVNDLDLPSSNNFEYSIIAGD-PMGMFEIN-SNGEITVSSLLDREQQETYQLTIELI 1978

Query: 661  D-GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN-SPIGTTIGEIRAHDPDEGP 718
            D   +PP  +T +  I + D ND+ P+F    +   ++E  S     +  + A+D D G 
Sbjct: 1979 DQTNSPPARTTTLAIITVGDENDNTPIFAETVIRVDVTEGPSSQNIPVYMLTANDIDLGL 2038

Query: 719  NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA--SP--PL 774
            N  + Y+I      + F +    G     + T   LD+E+   +Y L++ A   SP  P 
Sbjct: 2039 NRDIIYAIGSQQPQSHFQINPETGM----ISTTTALDWET-ISEYTLIVTATDQSPTEPR 2093

Query: 775  WNDVRVEILVTDVNDNAPV 793
                 V + V D+ND AP+
Sbjct: 2094 TGTATVIVSVNDINDGAPM 2112



 Score =  289 bits (708), Expect = 1e-75
 Identities = 236/752 (31%), Positives = 343/752 (45%), Gaps = 78/752 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTADT 69
            + V D NDH+P F   QY  +V E    GT V  +   D D + +  ++ YTI  +T + 
Sbjct: 3244 VTVTDANDHNPTFVPDQYSLTVTENEPPGTQVGAVITIDGDTLPEYTDIIYTI--LTGNG 3301

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            L                   F I+  +G + T   LDREK + Y + + A +   PV   
Sbjct: 3302 LGN-----------------FTINSTTGIITTATILDREKTSEYVLTIGAEN---PVGGT 3341

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             + TAT+ + + D NDN P F E  Y +S     +VT N ++  + A D D G N  + Y
Sbjct: 3342 -TGTATVSIIVRDVNDNTPTFEENPY-IS-----TVTTNTLLVDVHANDPDEGGNGIVIY 3394

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             I+ GN   +F ID+ +G ++LV  LD + +R+Y LV+   D G+P   + T + + I  
Sbjct: 3395 EIVSGNEDNRFQIDNRTGVITLVNPLDSQLIRNYTLVVIGHDLGNPRLQSNTTVDLRINY 3454

Query: 250  VNDNAPRFYTSLFQES---VSENVPIGYSIVRVQAYDADEGVNAELTYT-MTDKDYTGNV 305
            +  NAP  +    Q S   ++EN P+G  I+   A D D G N  + Y+ + + DY G +
Sbjct: 3455 LGLNAPPSFVRPNQGSTVFITENNPLGQLIINAFAVDDDVGANGVVDYSILPNFDYNGGL 3514

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
               I + P          LD ET   Y L V  TD  D     T                
Sbjct: 3515 ---IPVKP----------LDFETFTNYNLTVVVTD--DSGNRDTTYVAVTVTDANDHNPT 3559

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQNGRGL 422
            F+P QY + + E+EPPGT V  +   D D   E   + Y I  GN  G F+I S    G+
Sbjct: 3560 FVPDQYSLTVTENEPPGTQVGVVITIDGDTLPEYTDIIYTILTGNGLGNFTINSTT--GI 3617

Query: 423  ITVAQPLDFKQERRYVLTVSATDS-GGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
            IT A  LD ++   YVLT+ A +  GG + TA V I + D N+  P FE  PYT++V   
Sbjct: 3618 ITTATILDREKTSEYVLTIGAENPVGGTTGTATVSIIVRDVNDNTPTFEENPYTSTV--- 3674

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
                T ++ V A D D G N  + Y + S   NE     D +F I+ +TG IT    L+ 
Sbjct: 3675 -TTNTLLVDVHANDPDEGGNGIVIYEIVS--GNE-----DNRFTIDNRTGVITLVNPLES 3726

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP---VFKQQLYTANIMEDALVGT 598
            + +  Y L V   D G P L   T V++ +  +  N P   V   Q  T  I E+  +G 
Sbjct: 3727 QLIRNYTLVVIGHDLGNPQLQSNTTVDLRINYLGLNAPPSFVRPNQGSTVFITENNPLGL 3786

Query: 599  SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
             +    A D DVG NG + Y + P + +   F IDP +G I    + DRE   ++ L  V
Sbjct: 3787 LIINAFAVDDDVGANGVVDYSILP-NFDYSDFTIDPVTGDITILVSADREIKDSYTLTVV 3845

Query: 659  AIDGGTPPQSSTVIVHIKIEDINDSPPVFESD-------CLTFYISENSPIGTTIGEI-R 710
            A D G P  S++    I++ D ND+ P F           L   + EN+ I   +G +  
Sbjct: 3846 ATDRGDPNLSTSSTFVIRVLDENDNNPAFPRPDGMNNPIVLNLNVFENANISDLVGTVDG 3905

Query: 711  AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
            A D D G N  + Y I        F + +  G
Sbjct: 3906 AIDLDLGANGQIFYHIVDSTVGGIFVINSTTG 3937



 Score =  283 bits (695), Expect = 4e-74
 Identities = 242/857 (28%), Positives = 397/857 (46%), Gaps = 63/857 (7%)

Query: 61   TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVL-VKA 119
            +I + T +  +P+             + +F I+  +G L     LD E +    ++ V  
Sbjct: 532  SILVFTLNATDPDGDPITYDLFDDEARSIFTINQFTGQLYALPGLDYETLGNQVIITVSV 591

Query: 120  TDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA 179
            TD    ++D +  T  I+V I D ND  P F+       V E+   T    + ++  TD 
Sbjct: 592  TDG---INDPVPQT--IYVRITDVNDIAPTFTNLPNITYVFEN--ATFGSELYQVITTDE 644

Query: 180  DVGANSAIRYAII-------GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232
            D      + Y+I        G      FSI    G + L  +L+YE+++ Y + + A+D 
Sbjct: 645  DTFYGGFVTYSISLVTPSTPGSAPNNYFSIGETDGIIQLATSLNYEEIQQYFVTVVARDY 704

Query: 233  GS--PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290
            G+   S S+T  L +++ ++ D  P F  + +  ++ E +P+G ++  + A D D     
Sbjct: 705  GTGDTSLSSTATLTVSVLNIQDTNPVFINTPYDVTIPETLPVGSTVQTITATDPDSNDGN 764

Query: 291  ELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET---QAKYQLLVTATDGGDPPRS 347
             +TY +   D  G       ID  +G +  + Q+DR+     A Y L+V+A +      S
Sbjct: 765  IITYNLVVSDSQGY----FVIDQTTGIITVNSQMDRDNPVLPATYPLIVSAVETSSGGVS 820

Query: 348  -ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV-VTLTATDAD--EDNRLHYEI 403
             A  +              F    Y   + E     + + +T+T  D D   D+ +   +
Sbjct: 821  FAQVSFNVTVSPANDEPPMFDQNSYSASIPESASVNSQLPITITVNDGDLITDSTVTVSL 880

Query: 404  TGGNT-RGRFSITSQNGRGL--ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT 460
              GN+   R S T   G G   I + QPLDF+  ++Y L + A D  G+ D A + + +T
Sbjct: 881  QNGNSVPFRVSPTQVVGSGTVDILITQPLDFENNQQYTLQLQAVDGDGQ-DIAPLMVTVT 939

Query: 461  DANNYAPVFENAP----YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA 516
            D N+  PVF N P    Y  S+ E+   GT ++ VS TD+D G NA +TYS+ S   N  
Sbjct: 940  DVNDNNPVFINRPIDNIYRGSINENDQTGTFIVQVSTTDADSGSNAAVTYSIISGNINNV 999

Query: 517  VAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD---GGVPSL-SDTTDVEISVV 572
                   F INP +GAIT  ++L   T   Y L+V A +   G  P+  + T+ V I+V 
Sbjct: 1000 -------FTINPTSGAITNTQILGPNTPQTYTLSVRATNPTPGVAPATGTSTSTVIITVN 1052

Query: 573  DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632
            DVND+ P F    +T  I E A VGT+V+++ ATD D+    R+ Y +       G F I
Sbjct: 1053 DVNDSPPRFSDDEFTVFINEAAQVGTTVTRITATDEDIPEGDRLTY-IITAGNTGGHFQI 1111

Query: 633  DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692
            +P SG +   + LDRE  + H+L   A D G PPQS+T  + + + D ND+ P +     
Sbjct: 1112 NPVSGDVTLLRQLDRELESQHNLTIRATDQGAPPQSATTTLKVIVLDFNDNAPQWSPQSY 1171

Query: 693  TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752
               I EN P+ T + ++ A D D+G NA + ++I   ++   F ++     D+  + T  
Sbjct: 1172 VDSILENVPLNTFVLQVVATDADQGTNADLSFTINNANNV-PFVID-----DQGNIRTSG 1225

Query: 753  DLDYES-PRKKYEL-VIRAASPPLWND--VRVEILVTDVNDNAPVMKDFQIIFNNYKDCF 808
             L+ E+ P+  + + V+   SP    +    V I + DVND  PV+      F   +D  
Sbjct: 1226 PLNRETVPQYNFLVTVLDNGSPQQAGNPPATVTINILDVNDEPPVLDRNSYEFTVSEDVN 1285

Query: 809  PVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVS 868
                 G+V A D D++  L Y  +  +       +  +G++  + QL+ N  ++  M V 
Sbjct: 1286 FNTFVGQVTATDPDLSGTLTYTFVPADPD----FSYISGTIRTNTQLDANQQQVYQMTVF 1341

Query: 869  VTDGV-NEIKAMMQLSV 884
             +DGV N   A + ++V
Sbjct: 1342 ASDGVQNSQSAPVTINV 1358



 Score =  266 bits (651), Expect = 8e-69
 Identities = 261/885 (29%), Positives = 391/885 (44%), Gaps = 93/885 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I + D ND+ P F++  Y+ +V EG  S   ++T+ A D D  +N+ + Y I       L
Sbjct: 3146 IYINDLNDNQPTFDLPLYDVTVVEGQYSDP-IITVVANDPD--QNSNLRYEI---LGGNL 3199

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N                    +DG    L+    LD E    Y + V  TD +       
Sbjct: 3200 N---------------NTFVLVDG---GLIPVKPLDFETFTNYNLTVVVTDDSGN----- 3236

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
              T  + V + D ND+ P F    Y+++V E+       V A I      +   + I Y 
Sbjct: 3237 RDTTYVAVTVTDANDHNPTFVPDQYSLTVTEN-EPPGTQVGAVITIDGDTLPEYTDIIYT 3295

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD--GGSPSRSNTTQLLINIR 248
            I+ GN    F+I+S +G ++    LD E+   Y L I A++  GG+   + T  + I +R
Sbjct: 3296 ILTGNGLGNFTINSTTGIITTATILDREKTSEYVLTIGAENPVGGT---TGTATVSIIVR 3352

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            DVNDN P F  + +  +V+ N      +V V A D DEG N  + Y +     +GN D  
Sbjct: 3353 DVNDNTPTFEENPYISTVTTNT----LLVDVHANDPDEGGNGIVIYEIV----SGNEDNR 3404

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP-RSATATXXXXXXXXXXXXXXFM 367
              ID R+G +     LD +    Y L+V   D G+P  +S T                F+
Sbjct: 3405 FQIDNRTGVITLVNPLDSQLIRNYTLVVIGHDLGNPRLQSNTTVDLRINYLGLNAPPSFV 3464

Query: 368  -PGQYE-VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ---NGRGL 422
             P Q   V + E+ P G  ++   A D D          G N    +SI      NG GL
Sbjct: 3465 RPNQGSTVFITENNPLGQLIINAFAVDDD---------VGANGVVDYSILPNFDYNG-GL 3514

Query: 423  ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
            I V +PLDF+    Y LTV  TD  G  DT  V + +TDAN++ P F    Y+ +V E+ 
Sbjct: 3515 IPV-KPLDFETFTNYNLTVVVTDDSGNRDTTYVAVTVTDANDHNPTFVPDQYSLTVTENE 3573

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
            P GT V VV   D D     + T  + + ++   + +    F IN  TG ITT  +LDRE
Sbjct: 3574 PPGTQVGVVITIDGDT--LPEYTDIIYTILTGNGLGN----FTINSTTGIITTATILDRE 3627

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
              S Y+LT+ A +  V   + T  V I V DVNDN P F++  YT+ +  + L+      
Sbjct: 3628 KTSEYVLTIGA-ENPVGGTTGTATVSIIVRDVNDNTPTFEENPYTSTVTTNTLL----VD 3682

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
            V A D D G NG + YE+     E+  F ID  +GVI     L+ + +  + L  +  D 
Sbjct: 3683 VHANDPDEGGNGIVIYEI-VSGNEDNRFTIDNRTGVITLVNPLESQLIRNYTLVVIGHDL 3741

Query: 663  GTPPQSSTVIVHIKIEDIN-DSPPVF--ESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
            G P   S   V ++I  +  ++PP F   +   T +I+EN+P+G  I    A D D G N
Sbjct: 3742 GNPQLQSNTTVDLRINYLGLNAPPSFVRPNQGSTVFITENNPLGLLIINAFAVDDDVGAN 3801

Query: 720  AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWN 776
             VV YSI    D + F+++   G    ++  +V  D E  +  Y L + A     P L  
Sbjct: 3802 GVVDYSILPNFDYSDFTIDPVTG----DITILVSADREI-KDSYTLTVVATDRGDPNLST 3856

Query: 777  DVRVEILVTDVNDNAPV------MKDFQI----IFNNYKDCFPVGPFGRVPAYDADVTDK 826
                 I V D NDN P       M +  +    +F N      VG        D     +
Sbjct: 3857 SSTFVIRVLDENDNNPAFPRPDGMNNPIVLNLNVFENANISDLVGTVDGAIDLDLGANGQ 3916

Query: 827  LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            + Y I+      + ++N TTG +T++  L+     + T+ +  T+
Sbjct: 3917 IFYHIVDSTVGGIFVINSTTGVVTVNGTLDREDIGVHTIYILATN 3961



 Score =  264 bits (647), Expect = 2e-68
 Identities = 247/888 (27%), Positives = 397/888 (44%), Gaps = 81/888 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + + D ND +P F        V E A+ G+ +  +  TD+D      V Y+I LVT  T 
Sbjct: 605  VRITDVNDIAPTFTNLPNITYVFENATFGSELYQVITTDEDTFYGGFVTYSISLVTPST- 663

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             P  A            + F I    G +    SL+ E++ +Y V V A D  +     L
Sbjct: 664  -PGSA----------PNNYFSIGETDGIIQLATSLNYEEIQQYFVTVVARDYGTG-DTSL 711

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            SSTAT+ V++++  D  P F    Y V++ E + V     +  I ATD D    + I Y 
Sbjct: 712  SSTATLTVSVLNIQDTNPVFINTPYDVTIPETLPV--GSTVQTITATDPDSNDGNIITYN 769

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQ---VRSYRLVIRAQDGGSPSRS-NTTQLLIN 246
            ++  ++Q  F ID  +G +++   +D +      +Y L++ A +  S   S       + 
Sbjct: 770  LVVSDSQGYFVIDQTTGIITVNSQMDRDNPVLPATYPLIVSAVETSSGGVSFAQVSFNVT 829

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSI-VRVQAYDADEGVNAELTYTMTDKDYTGNV 305
            +   ND  P F  + +  S+ E+  +   + + +   D D   ++ +T ++ +    GN 
Sbjct: 830  VSPANDEPPMFDQNSYSASIPESASVNSQLPITITVNDGDLITDSTVTVSLQN----GN- 884

Query: 306  DLPITIDPR----SGWV--YTSGQLDRETQAKYQLLVTATDG-GDPPRSATATXXXXXXX 358
             +P  + P     SG V    +  LD E   +Y L + A DG G        T       
Sbjct: 885  SVPFRVSPTQVVGSGTVDILITQPLDFENNQQYTLQLQAVDGDGQDIAPLMVTVTDVNDN 944

Query: 359  XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITS 416
                    +   Y   + E++  GT +V ++ TDAD  +   + Y I  GN    F+I  
Sbjct: 945  NPVFINRPIDNIYRGSINENDQTGTFIVQVSTTDADSGSNAAVTYSIISGNINNVFTINP 1004

Query: 417  QNGRGLITVAQPLDFKQERRYVLTVSATD------SGGRSDTAMVQINITDANNYAPVFE 470
             +  G IT  Q L     + Y L+V AT+          + T+ V I + D N+  P F 
Sbjct: 1005 TS--GAITNTQILGPNTPQTYTLSVRATNPTPGVAPATGTSTSTVIITVNDVNDSPPRFS 1062

Query: 471  NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
            +  +T  + E A +GTTV  ++ATD D+    ++TY +++        +    F INP +
Sbjct: 1063 DDEFTVFINEAAQVGTTVTRITATDEDIPEGDRLTYIITA-------GNTGGHFQINPVS 1115

Query: 531  GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590
            G +T  + LDRE  S + LT+ A D G P  S TT +++ V+D NDN P +  Q Y  +I
Sbjct: 1116 GDVTLLRQLDRELESQHNLTIRATDQGAPPQSATTTLKVIVLDFNDNAPQWSPQSYVDSI 1175

Query: 591  MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650
            +E+  + T V QV ATDAD G N  + + ++  +     FVID   G IRT+  L+RE+V
Sbjct: 1176 LENVPLNTFVLQVVATDADQGTNADLSFTIN--NANNVPFVIDD-QGNIRTSGPLNRETV 1232

Query: 651  ATHDLKAVAIDGGTPPQSST--VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
              ++     +D G+P Q+      V I I D+ND PPV + +   F +SE+    T +G+
Sbjct: 1233 PQYNFLVTVLDNGSPQQAGNPPATVTINILDVNDEPPVLDRNSYEFTVSEDVNFNTFVGQ 1292

Query: 709  IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768
            + A DPD   +  + Y+    D   S+   T        + T   LD  + ++ Y++ + 
Sbjct: 1293 VTATDPD--LSGTLTYTFVPADPDFSYISGT--------IRTNTQLD-ANQQQVYQMTV- 1340

Query: 769  AASPPLWN--DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK 826
             AS  + N     V I V DVN+ AP    F +    Y    P     +    D + TD 
Sbjct: 1341 FASDGVQNSQSAPVTINVLDVNNQAP---SFGL--GTYVKSLPEDSPFQTLVVDLNATDP 1395

Query: 827  LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN 874
                     N  LI+ +  + S T  P   T  P    +E+S T G++
Sbjct: 1396 ------DNGNTGLIIYSFESLSRTQGP--FTVDPYTGVVEISTTAGLD 1435



 Score =  261 bits (639), Expect = 2e-67
 Identities = 247/875 (28%), Positives = 377/875 (43%), Gaps = 85/875 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + ++D ND++PVF  Q +  ++ E    G  V  + ATD D G +  V Y+  L+  D  
Sbjct: 2929 LEIIDNNDNNPVFGAQSHTTTIIESEPIGAFVFNVNATDADSGGSGRVTYS--LIGGD-- 2984

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F I+  SG +     +D+E  +++ + V A D      D  
Sbjct: 2985 -----------------GKFTINQDSGVITLLQQVDKETQSQHMLTVFARDNPGDSEDSR 3027

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV--GANSAIR 188
            + + T+ VN++D N+  P  ++  +T+    D       V+  I+A D D     N ++ 
Sbjct: 3028 TGSTTVIVNVLDANEFPPVVTQPIFTI----DEGGIGGEVVGVIEAYDPDDPDDPNQSLY 3083

Query: 189  YAIIGGNTQMQ---FSIDSLSGDVSLVKTLDYEQ-VRSYR--LVIRAQDGGSPSRSNTTQ 242
            Y ++    ++    F I++ +G++     LD +  +   R  L +   D G+P+    T 
Sbjct: 3084 YVVVSSQPEVGGTLFIINNATGEIITTGPLDRDNNLHPARVDLDVIVYDDGNPNLGTPTT 3143

Query: 243  LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
             +I I D+NDN P F   L+  +V E       I+ V A D D+  N+ L Y +      
Sbjct: 3144 AIIYINDLNDNQPTFDLPLYDVTVVEG-QYSDPIITVVANDPDQ--NSNLRYEILG---- 3196

Query: 303  GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
            GN++    +    G +     LD ET   Y L V  TD  D     T             
Sbjct: 3197 GNLNNTFVLV--DGGLIPVKPLDFETFTNYNLTVVVTD--DSGNRDTTYVAVTVTDANDH 3252

Query: 363  XXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQNG 419
               F+P QY + + E+EPPGT V  +   D D   E   + Y I  GN  G F+I S  G
Sbjct: 3253 NPTFVPDQYSLTVTENEPPGTQVGAVITIDGDTLPEYTDIIYTILTGNGLGNFTINSTTG 3312

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDS-GGRSDTAMVQINITDANNYAPVFENAPYTASV 478
              +IT A  LD ++   YVLT+ A +  GG + TA V I + D N+  P FE  PY ++V
Sbjct: 3313 --IITTATILDREKTSEYVLTIGAENPVGGTTGTATVSIIVRDVNDNTPTFEENPYISTV 3370

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
              +    T ++ V A D D G N  + Y + S   NE     D +F I+ +TG IT    
Sbjct: 3371 TTN----TLLVDVHANDPDEGGNGIVIYEIVS--GNE-----DNRFQIDNRTGVITLVNP 3419

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP---VFKQQLYTANIMEDAL 595
            LD + +  Y L V   D G P L   T V++ +  +  N P   V   Q  T  I E+  
Sbjct: 3420 LDSQLIRNYTLVVIGHDLGNPRLQSNTTVDLRINYLGLNAPPSFVRPNQGSTVFITENNP 3479

Query: 596  VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655
            +G  +    A D DVG NG + Y + P          D   G+I   K LD E+   ++L
Sbjct: 3480 LGQLIINAFAVDDDVGANGVVDYSILPN--------FDYNGGLIPV-KPLDFETFTNYNL 3530

Query: 656  KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
              V  D        T  V + + D ND  P F  D  +  ++EN P GT +G +   D D
Sbjct: 3531 TVVVTDDSG--NRDTTYVAVTVTDANDHNPTFVPDQYSLTVTENEPPGTQVGVVITIDGD 3588

Query: 716  EGPNAV-VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP- 773
              P    + Y+I  G+   +F++ +  G     + T   LD E    +Y L I A +P  
Sbjct: 3589 TLPEYTDIIYTILTGNGLGNFTINSTTGI----ITTATILDREKT-SEYVLTIGAENPVG 3643

Query: 774  -LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRIL 832
                   V I+V DVNDN P  ++         +   V      P  D      + Y I+
Sbjct: 3644 GTTGTATVSIIVRDVNDNTPTFEENPYTSTVTTNTLLVDVHANDP--DEGGNGIVIYEIV 3701

Query: 833  SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867
            SGN  N   ++  TG +TL   L + + +  T+ V
Sbjct: 3702 SGNEDNRFTIDNRTGVITLVNPLESQLIRNYTLVV 3736



 Score =  257 bits (629), Expect = 4e-66
 Identities = 249/881 (28%), Positives = 383/881 (43%), Gaps = 73/881 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            IN+LD ND  PV +   YE +V E  +  T V  + ATD D+  +  + YT   V AD  
Sbjct: 1259 INILDVNDEPPVLDRNSYEFTVSEDVNFNTFVGQVTATDPDL--SGTLTYTF--VPAD-- 1312

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             P+ +                    SG + T   LD  +   Y + V A+D         
Sbjct: 1313 -PDFSYI------------------SGTIRTNTQLDANQQQVYQMTVFASDGVQN----- 1348

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S +A + +N++D N+  P F   TY  S+ ED       ++  + ATD D G    I Y+
Sbjct: 1349 SQSAPVTINVLDVNNQAPSFGLGTYVKSLPEDSPF--QTLVVDLNATDPDNGNTGLIIYS 1406

Query: 191  IIG-GNTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQD---GGSPSRSNTTQLL 244
                  TQ  F++D  +G V +  T  LD E    Y +++ A D    G P     T  +
Sbjct: 1407 FESLSRTQGPFTVDPYTGVVEISTTAGLDRETQDEYTMIVIAVDQPASGQPMTGTATVSV 1466

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
            I + DVNDNAP F    ++ES+ EN P+G +I+ VQA D D GVNA + Y +     +GN
Sbjct: 1467 I-VTDVNDNAPTFRDISYEESIFENHPLGSNILTVQADDPDLGVNAVVLYRII----SGN 1521

Query: 305  VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
             +    +D +      S  LDRE Q +Y L+V A +      +                 
Sbjct: 1522 NNNLFNVDGQGNINLGSTPLDREMQDQYFLIVQAYNSDLSVGTNEVPVIINILDINDVTP 1581

Query: 365  XFMP-GQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRG 421
             F     Y  +L+E+ P GTPV+ + A D D D    + Y + G        +T  +  G
Sbjct: 1582 LFQQQNYYRPDLSENSPSGTPVLQVFAQDQDLDLAGDVQYSLIGNPN----FLTINSDTG 1637

Query: 422  LITVAQPL-DFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASV 478
            +I+V  P+ D    R + +TV ATD         A V + + D     P+F  + Y A+V
Sbjct: 1638 VISVNGPIADLSGSRNFTMTVRATDQASPFLRGVATVTVTVVDDTVTIPIFTLSRYPATV 1697

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             E+    T V  VSAT +  G  A ITY++    S   +    + F I+  TG ITT   
Sbjct: 1698 IENVNADTPVTRVSATLN--GNPAGITYAIDPNASPAVL----EIFKIDENTGHITTEGA 1751

Query: 539  LDRETMSGYLLTVTA--RDGGVPSLSDTTDVEISVVDVNDNEPVF-KQQLYTANIMEDAL 595
            +DRE    Y  TV A   D   P    +T V ++++D NDN P F        ++ E+  
Sbjct: 1752 IDREVEDFYAFTVFAYHEDSVAPG---STSVWVNILDENDNPPEFITVPPSPVSVRENTG 1808

Query: 596  VGTSVSQVGATDADVGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKALDRESVATHD 654
                V    ATD D G+N ++ + +        + F      G I     LDRE    + 
Sbjct: 1809 GNVPVGLFRATDPDAGINAQMTFSISGAGSNFFNVFQTANGGGTIVVTSPLDRERQDFYQ 1868

Query: 655  LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
            L   A DGG P  SS+  ++I + D+ND+ P++  +     I+EN+     I  +  +D 
Sbjct: 1869 LTVTATDGGNPSLSSSFPLNITVTDVNDNYPIWTRNVYEGSINENNFTSNPIITVMVNDL 1928

Query: 715  DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY-ESPRKKYELVIRAASPP 773
            D   +    YSI  GD    F + +   + +  + +++D +  E+ +   EL+ +  SPP
Sbjct: 1929 DLPSSNNFEYSIIAGDPMGMFEINS---NGEITVSSLLDREQQETYQLTIELIDQTNSPP 1985

Query: 774  LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYR 830
                    I V D NDN P+  +  I  +  +       P   + A D D  +   + Y 
Sbjct: 1986 ARTTTLAIITVGDENDNTPIFAETVIRVDVTEGPSSQNIPVYMLTANDIDLGLNRDIIYA 2045

Query: 831  ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            I S    +   +N  TG ++ +  L+       T+ V+ TD
Sbjct: 2046 IGSQQPQSHFQINPETGMISTTTALDWETISEYTLIVTATD 2086



 Score =  255 bits (624), Expect = 1e-65
 Identities = 230/796 (28%), Positives = 359/796 (45%), Gaps = 59/796 (7%)

Query: 117  VKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKA 176
            +  T  +   ++  +    + +N+I+ ND+ P F    YT+++ ++IS      +  ++A
Sbjct: 2361 IDQTIDSMGATEEKTGQTLVGINVININDHTPIFEGIPYTITLSKNISAGSLAYV--VRA 2418

Query: 177  TDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD--GGS 234
            TD D G    +RY I  GNT   F ID  +G    V      +  +YRLV+ A+D  G  
Sbjct: 2419 TDDDAGIFGEVRYQITDGNTDNIFRIDQTTGQTGEVFVQGLLETGTYRLVVEARDTPGDI 2478

Query: 235  P-SRSNTTQLLINIRDVNDNAPRF-YTSLFQESVSENVPIGYSIVRVQAYDA-DEGVNAE 291
            P SR+++T L I + D+ D AP F  +SLF  +V EN P+G  I  +    A +     +
Sbjct: 2479 PSSRASSTTLTIVVTDIGDLAPTFPGSSLFTGNVFENAPVGQPITMIPPIRAINSDATGQ 2538

Query: 292  LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
            L YT+T  D          I+  S  +  +G LDRET+  Y+  V  TD      +A  T
Sbjct: 2539 LVYTITGPD-----SQTFMINQLSAGIQVNGPLDRETKDFYEFGVIVTD--SMGLTAMGT 2591

Query: 352  XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGR 411
                          F    Y   + E+ P G  V  ++A D D DN   +  TGG    +
Sbjct: 2592 VHINVLDVNDFAPAFNDSVYNFTIPENSPGGYYVGGVSAYDLDGDNVNFFIQTGG--EDK 2649

Query: 412  FSITSQNGRGLITVAQPLDFKQERRYVLTVSATD--SGGRSDTAMVQINITDANNYAPVF 469
            F I   +G   +T    LD +++  Y LTV  +D  +   S TA V I + D N+  P F
Sbjct: 2650 FDIGGTSGTITVTPGAVLDREEKPFYTLTVMVSDLRNPPLSGTATVYIYLIDINDSPPKF 2709

Query: 470  ENA--PYTASVFEDAPIGTTVLVVSATDSDV--GINAQI-TYSLSSEISNEAVAHHDQQ- 523
            + +      S+ ED P  T V  V+ATD D+   IN QI + S+  E   +  +  D + 
Sbjct: 2710 DASFLDQIISIPEDTPGNTIVTTVTATDDDLNSNINYQIVSVSVYDEDDVDITSFFDYRT 2769

Query: 524  -FVINPQTGAITTNKLLDRETMSGYLLTVTARDGG-----VPSLSDTTDVEISVVDVNDN 577
             F +NP  G IT    +DRE    ++ +++ARD         +  +   V I + D+NDN
Sbjct: 2770 VFSLNPTNGNITLTSPVDREVTEKFVFSISARDLNSQNPIFGTSQENAQVTILITDINDN 2829

Query: 578  EPVFKQQLYT---ANIMEDALVGTSV-SQVGATDADVGLNGRIHYELDPKDREEGSFVID 633
             P F+    T     + E    G+ +   + A D D+GLNG + Y +  ++       ID
Sbjct: 2830 HPAFQPPGTTFILRQLPESFGAGSPIPGNLLALDPDLGLNGEVMYII--QNPSGVPVTID 2887

Query: 634  PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693
              +G +     +DRE     +L  +A+D GTP  ++++ V+++I D ND+ PVF +   T
Sbjct: 2888 QNTGQLTLLVTVDREQQPWVNLTVLAVDKGTPSLNTSIPVYLEIIDNNDNNPVFGAQSHT 2947

Query: 694  FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753
              I E+ PIG  +  + A D D G +  V YS+ GGD    F++      D   +  +  
Sbjct: 2948 TTIIESEPIGAFVFNVNATDADSGGSGRVTYSLIGGD--GKFTI----NQDSGVITLLQQ 3001

Query: 754  LDYESPRKKYELVIRAASPPLWNDVR-----VEILVTDVNDNAPVMKDFQIIFNNYKDCF 808
            +D E+  +    V    +P    D R     V + V D N+  PV+   Q IF   +   
Sbjct: 3002 VDKETQSQHMLTVFARDNPGDSEDSRTGSTTVIVNVLDANEFPPVVT--QPIFTIDEGGI 3059

Query: 809  PVGPFGRVPAYDADVTD----KLQYRILSGN---NANLILLNETTGSMTLSPQL---NTN 858
                 G + AYD D  D     L Y ++S        L ++N  TG +  +  L   N  
Sbjct: 3060 GGEVVGVIEAYDPDDPDDPNQSLYYVVVSSQPEVGGTLFIINNATGEIITTGPLDRDNNL 3119

Query: 859  VPKLATMEVSVTDGVN 874
             P    ++V V D  N
Sbjct: 3120 HPARVDLDVIVYDDGN 3135



 Score =  247 bits (604), Expect = 4e-63
 Identities = 254/897 (28%), Positives = 389/897 (43%), Gaps = 98/897 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            INVLD ND +P F    Y  ++ E +  G  V  + A D D G N  V + I+       
Sbjct: 2594 INVLDVNDFAPAFNDSVYNFTIPENSPGGYYVGGVSAYDLD-GDN--VNFFIQ------- 2643

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR--ASLDREKVARYTVLVKATDQASPVSD 128
                            +D F I G SG +     A LDRE+   YT+ V  +D  +P   
Sbjct: 2644 -------------TGGEDKFDIGGTSGTITVTPGAVLDREEKPFYTLTVMVSDLRNP--- 2687

Query: 129  RLSSTATIHVNIIDDNDNYPQF--SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
             LS TAT+++ +ID ND+ P+F  S     +S+ ED     N ++  + ATD D+  NS 
Sbjct: 2688 PLSGTATVYIYLIDINDSPPKFDASFLDQIISIPED--TPGNTIVTTVTATDDDL--NSN 2743

Query: 187  IRYAIIGGNT--------------QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232
            I Y I+  +               +  FS++  +G+++L   +D E    +   I A+D 
Sbjct: 2744 INYQIVSVSVYDEDDVDITSFFDYRTVFSLNPTNGNITLTSPVDREVTEKFVFSISARDL 2803

Query: 233  GSP-----SRSNTTQLLINIRDVNDNAPRFY---TSLFQESVSENVPIGYSIV-RVQAYD 283
             S      +     Q+ I I D+NDN P F    T+     + E+   G  I   + A D
Sbjct: 2804 NSQNPIFGTSQENAQVTILITDINDNHPAFQPPGTTFILRQLPESFGAGSPIPGNLLALD 2863

Query: 284  ADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD 343
             D G+N E+ Y + +        +P+TID  +G +     +DRE Q    L V A D G 
Sbjct: 2864 PDLGLNGEVMYIIQNPS-----GVPVTIDQNTGQLTLLVTVDREQQPWVNLTVLAVDKGT 2918

Query: 344  PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHY 401
            P  + +                F    +   + E EP G  V  + ATDAD     R+ Y
Sbjct: 2919 PSLNTSIPVYLEIIDNNDNNPVFGAQSHTTTIIESEPIGAFVFNVNATDADSGGSGRVTY 2978

Query: 402  EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG-----RSDTAMVQ 456
             + GG+  G+F+I   +  G+IT+ Q +D + + +++LTV A D+ G     R+ +  V 
Sbjct: 2979 SLIGGD--GKFTINQDS--GVITLLQQVDKETQSQHMLTVFARDNPGDSEDSRTGSTTVI 3034

Query: 457  INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA 516
            +N+ DAN + PV     +T  + E    G  V V+ A D D   +     SL   + +  
Sbjct: 3035 VNVLDANEFPPVVTQPIFT--IDEGGIGGEVVGVIEAYDPDDPDDP--NQSLYYVVVSSQ 3090

Query: 517  VAHHDQQFVINPQTGAITTNKLLDRET---MSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
                   F+IN  TG I T   LDR+     +   L V   D G P+L   T   I + D
Sbjct: 3091 PEVGGTLFIINNATGEIITTGPLDRDNNLHPARVDLDVIVYDDGNPNLGTPTTAIIYIND 3150

Query: 574  VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633
            +NDN+P F   LY   ++E       ++ V A D D   N  + YE+   +      ++D
Sbjct: 3151 LNDNQPTFDLPLYDVTVVEGQYSDPIITVV-ANDPD--QNSNLRYEILGGNLNNTFVLVD 3207

Query: 634  PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693
               G+I   K LD E+   ++L  V  D        T  V + + D ND  P F  D  +
Sbjct: 3208 --GGLIPV-KPLDFETFTNYNLTVVVTDDS--GNRDTTYVAVTVTDANDHNPTFVPDQYS 3262

Query: 694  FYISENSPIGTTIGEIRAHDPDEGPNAV-VHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752
              ++EN P GT +G +   D D  P    + Y+I  G+   +F++ +  G     + T  
Sbjct: 3263 LTVTENEPPGTQVGAVITIDGDTLPEYTDIIYTILTGNGLGNFTINSTTGI----ITTAT 3318

Query: 753  DLDYESPRKKYELVIRAASP--PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV 810
             LD E    +Y L I A +P         V I+V DVNDN P  ++   I     +   V
Sbjct: 3319 ILDREK-TSEYVLTIGAENPVGGTTGTATVSIIVRDVNDNTPTFEENPYISTVTTNTLLV 3377

Query: 811  GPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867
                  P  D      + Y I+SGN  N   ++  TG +TL   L++ + +  T+ V
Sbjct: 3378 DVHANDP--DEGGNGIVIYEIVSGNEDNRFQIDNRTGVITLVNPLDSQLIRNYTLVV 3432



 Score =  239 bits (586), Expect = 6e-61
 Identities = 201/722 (27%), Positives = 325/722 (45%), Gaps = 45/722 (6%)

Query: 13   VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72
            V D ND++P F    YE S+ E    G+ +LT++A D D+G NA V Y I  ++ +  N 
Sbjct: 1468 VTDVNDNAPTFRDISYEESIFENHPLGSNILTVQADDPDLGVNAVVLYRI--ISGNNNN- 1524

Query: 73   EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132
                            +F +DG+    L    LDRE   +Y ++V+A +    V    ++
Sbjct: 1525 ----------------LFNVDGQGNINLGSTPLDREMQDQYFLIVQAYNSDLSVG---TN 1565

Query: 133  TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192
               + +NI+D ND  P F ++ Y      + S +  PV+ ++ A D D+     ++Y++I
Sbjct: 1566 EVPVIINILDINDVTPLFQQQNYYRPDLSENSPSGTPVL-QVFAQDQDLDLAGDVQYSLI 1624

Query: 193  GGNTQMQFSIDSLSGDVSLVKTL-DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251
            G    +  +I+S +G +S+   + D    R++ + +RA D  SP       + + + D  
Sbjct: 1625 GNPNFL--TINSDTGVISVNGPIADLSGSRNFTMTVRATDQASPFLRGVATVTVTVVDDT 1682

Query: 252  DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311
               P F  S +  +V ENV     + RV A     G  A +TY +        +++   I
Sbjct: 1683 VTIPIFTLSRYPATVIENVNADTPVTRVSA--TLNGNPAGITYAIDPNASPAVLEI-FKI 1739

Query: 312  DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371
            D  +G + T G +DRE +  Y   V A         +T+                     
Sbjct: 1740 DENTGHITTEGAIDREVEDFYAFTVFAYHEDSVAPGSTSVWVNILDENDNPPEFITVPPS 1799

Query: 372  EVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
             V + E+     PV    ATD D   + ++ + I+G  +       + NG G I V  PL
Sbjct: 1800 PVSVRENTGGNVPVGLFRATDPDAGINAQMTFSISGAGSNFFNVFQTANGGGTIVVTSPL 1859

Query: 430  DFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTT 487
            D +++  Y LTV+ATD G  S ++   +NIT  D N+  P++    Y  S+ E+      
Sbjct: 1860 DRERQDFYQLTVTATDGGNPSLSSSFPLNITVTDVNDNYPIWTRNVYEGSINENNFTSNP 1919

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
            ++ V   D D+  +    YS+   I+ + +      F IN   G IT + LLDRE    Y
Sbjct: 1920 IITVMVNDLDLPSSNNFEYSI---IAGDPMG----MFEIN-SNGEITVSSLLDREQQETY 1971

Query: 548  LLTVTARDG-GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED-ALVGTSVSQVGA 605
             LT+   D    P    TT   I+V D NDN P+F + +   ++ E  +     V  + A
Sbjct: 1972 QLTIELIDQTNSPPARTTTLAIITVGDENDNTPIFAETVIRVDVTEGPSSQNIPVYMLTA 2031

Query: 606  TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG-T 664
             D D+GLN  I Y +  + + +  F I+P +G+I T  ALD E+++ + L   A D   T
Sbjct: 2032 NDIDLGLNRDIIYAIGSQ-QPQSHFQINPETGMISTTTALDWETISEYTLIVTATDQSPT 2090

Query: 665  PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
             P++ T  V + + DIND  P+F  D    Y        + I   +A D D+G    V Y
Sbjct: 2091 EPRTGTATVIVSVNDINDGAPMFVRDVYGPYSVVEEVSNSYIDSFQATDTDQGLAGTVTY 2150

Query: 725  SI 726
            S+
Sbjct: 2151 SV 2152



 Score =  239 bits (584), Expect = 1e-60
 Identities = 224/807 (27%), Positives = 356/807 (44%), Gaps = 68/807 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEA--SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68
            I ++D ND  P F+    +   S+ E     T V T+ ATD D+  N+ + Y  ++V+  
Sbjct: 2697 IYLIDINDSPPKFDASFLDQIISIPEDTPGNTIVTTVTATDDDL--NSNINY--QIVSVS 2752

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS--PV 126
              + +D            + VF ++  +G +   + +DRE   ++   + A D  S  P+
Sbjct: 2753 VYDEDDVDITSFFDY---RTVFSLNPTNGNITLTSPVDREVTEKFVFSISARDLNSQNPI 2809

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEK--TYTVSVDEDISVTDNPVIAKIKATDADVGAN 184
                   A + + I D NDN+P F     T+ +    +     +P+   + A D D+G N
Sbjct: 2810 FGTSQENAQVTILITDINDNHPAFQPPGTTFILRQLPESFGAGSPIPGNLLALDPDLGLN 2869

Query: 185  SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
              + Y II   + +  +ID  +G ++L+ T+D EQ     L + A D G+PS + +  + 
Sbjct: 2870 GEVMY-IIQNPSGVPVTIDQNTGQLTLLVTVDREQQPWVNLTVLAVDKGTPSLNTSIPVY 2928

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
            + I D NDN P F       ++ E+ PIG  +  V A DAD G +  +TY++   D  G 
Sbjct: 2929 LEIIDNNDNNPVFGAQSHTTTIIESEPIGAFVFNVNATDADSGGSGRVTYSLIGGD--GK 2986

Query: 305  VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG-GDPPRSATATXXXXXXXXXXXX 363
                 TI+  SG +    Q+D+ETQ+++ L V A D  GD   S T +            
Sbjct: 2987 ----FTINQDSGVITLLQQVDKETQSQHMLTVFARDNPGDSEDSRTGSTTVIVNVLDANE 3042

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADE----DNRLHYEITGGNTR-GRFSITSQN 418
               +  Q    + E    G  V  + A D D+    +  L+Y +       G       N
Sbjct: 3043 FPPVVTQPIFTIDEGGIGGEVVGVIEAYDPDDPDDPNQSLYYVVVSSQPEVGGTLFIINN 3102

Query: 419  GRGLITVAQPLDFKQE---RRYVLTVSATDSG----GRSDTAMVQINITDANNYAPVFEN 471
              G I    PLD        R  L V   D G    G   TA++ IN  D N+  P F+ 
Sbjct: 3103 ATGEIITTGPLDRDNNLHPARVDLDVIVYDDGNPNLGTPTTAIIYIN--DLNDNQPTFDL 3160

Query: 472  APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS-LSSEISNEAVAHHDQQFVINPQT 530
              Y  +V E       ++ V A D D   N+ + Y  L   ++N         FV+    
Sbjct: 3161 PLYDVTVVE-GQYSDPIITVVANDPDQ--NSNLRYEILGGNLNN--------TFVL--VD 3207

Query: 531  GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590
            G +   K LD ET + Y LTV   D       DTT V ++V D ND+ P F    Y+  +
Sbjct: 3208 GGLIPVKPLDFETFTNYNLTVVVTDDS--GNRDTTYVAVTVTDANDHNPTFVPDQYSLTV 3265

Query: 591  MEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES 649
             E+   GT V  V   D D +     I Y +       G+F I+  +G+I T   LDRE 
Sbjct: 3266 TENEPPGTQVGAVITIDGDTLPEYTDIIYTI-LTGNGLGNFTINSTTGIITTATILDREK 3324

Query: 650  VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
             + + L  +  +      + T  V I + D+ND+ P FE +     ++ N    T + ++
Sbjct: 3325 TSEYVL-TIGAENPVGGTTGTATVSIIVRDVNDNTPTFEENPYISTVTTN----TLLVDV 3379

Query: 710  RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVI- 767
             A+DPDEG N +V Y I  G++ N F ++ R G     ++T+V+ LD +  R  Y LV+ 
Sbjct: 3380 HANDPDEGGNGIVIYEIVSGNEDNRFQIDNRTG-----VITLVNPLDSQLIR-NYTLVVI 3433

Query: 768  --RAASPPLWNDVRVEILVTDVNDNAP 792
                 +P L ++  V++ +  +  NAP
Sbjct: 3434 GHDLGNPRLQSNTTVDLRINYLGLNAP 3460



 Score =  231 bits (565), Expect = 2e-58
 Identities = 226/756 (29%), Positives = 339/756 (44%), Gaps = 93/756 (12%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND++P FE   Y ++V    ++ T ++ + A D D G N  V Y  E+V+ +  
Sbjct: 3349 IIVRDVNDNTPTFEENPYISTV----TTNTLLVDVHANDPDEGGNGIVIY--EIVSGN-- 3400

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
              ED             + F+ID R+G +     LD + +  YT++V   D  +P   RL
Sbjct: 3401 --ED-------------NRFQIDNRTGVITLVNPLDSQLIRNYTLVVIGHDLGNP---RL 3442

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDN----PVIAKIKATDADVGANSA 186
             S  T+ + I     N P    +    S    + +T+N     +I    A D DVGAN  
Sbjct: 3443 QSNTTVDLRINYLGLNAPPSFVRPNQGST---VFITENNPLGQLIINAFAVDDDVGANGV 3499

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            + Y+I+        + D  +G +  VK LD+E   +Y L +   D       +TT + + 
Sbjct: 3500 VDYSILP-------NFD-YNGGLIPVKPLDFETFTNYNLTVVVTDDSG--NRDTTYVAVT 3549

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN-AELTYTMTDKDYTGNV 305
            + D ND+ P F    +  +V+EN P G  +  V   D D      ++ YT+   +  GN 
Sbjct: 3550 VTDANDHNPTFVPDQYSLTVTENEPPGTQVGVVITIDGDTLPEYTDIIYTILTGNGLGN- 3608

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD--GGDPPRSATATXXXXXXXXXXXX 363
                TI+  +G + T+  LDRE  ++Y L + A +  GG    + TAT            
Sbjct: 3609 ---FTINSTTGIITTATILDREKTSEYVLTIGAENPVGGT---TGTATVSIIVRDVNDNT 3662

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRG 421
              F    Y   +  +    T +V + A D DE     + YEI  GN   RF+I   N  G
Sbjct: 3663 PTFEENPYTSTVTTN----TLLVDVHANDPDEGGNGIVIYEIVSGNEDNRFTI--DNRTG 3716

Query: 422  LITVAQPLDFKQERRYVLTVSATDSGG---RSDTAM-VQINITDANNYAPVFENAPYTAS 477
            +IT+  PL+ +  R Y L V   D G    +S+T + ++IN    N   P F      ++
Sbjct: 3717 VITLVNPLESQLIRNYTLVVIGHDLGNPQLQSNTTVDLRINYLGLNA-PPSFVRPNQGST 3775

Query: 478  VF--EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
            VF  E+ P+G  ++   A D DVG N  + YS+               F I+P TG IT 
Sbjct: 3776 VFITENNPLGLLIINAFAVDDDVGANGVVDYSILPNFDYS-------DFTIDPVTGDITI 3828

Query: 536  NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ-------LYTA 588
                DRE    Y LTV A D G P+LS ++   I V+D NDN P F +        +   
Sbjct: 3829 LVSADREIKDSYTLTVVATDRGDPNLSTSSTFVIRVLDENDNNPAFPRPDGMNNPIVLNL 3888

Query: 589  NIMEDALVGTSVSQV-GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647
            N+ E+A +   V  V GA D D+G NG+I Y +       G FVI+  +GV+  N  LDR
Sbjct: 3889 NVFENANISDLVGTVDGAIDLDLGANGQIFYHI-VDSTVGGIFVINSTTGVVTVNGTLDR 3947

Query: 648  ESVATHDLKAVAID----GGTPPQS-----STVIVHIKIEDINDSPPVFESDCLTFYISE 698
            E +  H +  +A +     GT P +     S   V I + DIND+ P F S  ++  I  
Sbjct: 3948 EDIGVHTIYILATNDATYNGTGPYNVLDNISLKEVKITLLDINDNAPRFTSTVISACIPF 4007

Query: 699  NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734
            +  +G T+  +   D D G N  + YS+      NS
Sbjct: 4008 DISLGMTVVSVAVVDLDGGTNLGIAYSLNSIQFINS 4043



 Score =  212 bits (517), Expect = 1e-52
 Identities = 231/840 (27%), Positives = 362/840 (43%), Gaps = 100/840 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASS-GTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            I V D ND++P+F        V EG SS    V  L A D D+G N ++ Y I      +
Sbjct: 1994 ITVGDENDNTPIFAETVIRVDVTEGPSSQNIPVYMLTANDIDLGLNRDIIYAI-----GS 2048

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
              P              Q  F+I+  +G + T  +LD E ++ YT++V ATDQ SP   R
Sbjct: 2049 QQP--------------QSHFQINPETGMISTTTALDWETISEYTLIVTATDQ-SPTEPR 2093

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTY-TVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             + TAT+ V++ D ND  P F    Y   SV E++S   N  I   +ATD D G    + 
Sbjct: 2094 -TGTATVIVSVNDINDGAPMFVRDVYGPYSVVEEVS---NSYIDSFQATDTDQGLAGTVT 2149

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            Y++I     +         DV    ++  E   SY    +A D         T  +I   
Sbjct: 2150 YSVIVSVNDINDGAPMFVRDVYGPYSVVEEVSNSYIDSFQATDTDQGLAGMVTYSVIGQ- 2208

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
                     Y+ LF       V    +I   +A D +      +T   TD          
Sbjct: 2209 ---------YSDLFFIQPQTGV---LTIRPDRALDYETITEFNITVVATDMGVPA----- 2251

Query: 309  ITIDPRSG--WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
            ++  P++G   +     LD ET  ++ + V ATD G+P  S++                F
Sbjct: 2252 LSSSPQTGVLTIRPDRALDYETITEFNITVVATDMGNPALSSSTLVGINVININDHTPIF 2311

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLIT 424
                Y + L+++   G+    + ATD D      + Y+IT GNT   F I          
Sbjct: 2312 EGIPYTITLSKNISAGSLAYVVRATDDDAGIFGEVRYQITDGNTDNIFRID--------- 2362

Query: 425  VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
              Q +D         ++ AT+   ++   +V IN+ + N++ P+FE  PYT ++ ++   
Sbjct: 2363 --QTID---------SMGATEE--KTGQTLVGINVININDHTPIFEGIPYTITLSKNISA 2409

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            G+   VV ATD D GI  ++ Y + ++ + + +   DQ      QTG +    LL+  T 
Sbjct: 2410 GSLAYVVRATDDDAGIFGEVRYQI-TDGNTDNIFRIDQ---TTGQTGEVFVQGLLETGT- 2464

Query: 545  SGYLLTVTARD--GGVP-SLSDTTDVEISVVDVNDNEPVFK-QQLYTANIMEDALVGTSV 600
              Y L V ARD  G +P S + +T + I V D+ D  P F    L+T N+ E+A VG  +
Sbjct: 2465 --YRLVVEARDTPGDIPSSRASSTTLTIVVTDIGDLAPTFPGSSLFTGNVFENAPVGQPI 2522

Query: 601  SQVGATDA-DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
            + +    A +    G++ Y +   D +  +F+I+  S  I+ N  LDRE+   ++   + 
Sbjct: 2523 TMIPPIRAINSDATGQLVYTITGPDSQ--TFMINQLSAGIQVNGPLDRETKDFYEFGVIV 2580

Query: 660  IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
             D        T  VHI + D+ND  P F      F I ENSP G  +G + A+D D G N
Sbjct: 2581 TDSMGLTAMGT--VHINVLDVNDFAPAFNDSVYNFTIPENSPGGYYVGGVSAYDLD-GDN 2637

Query: 720  AVVHYSIK-GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDV 778
              V++ I+ GG+D   F +    G+       ++D + +       +V    +PPL    
Sbjct: 2638 --VNFFIQTGGED--KFDIGGTSGTITVTPGAVLDREEKPFYTLTVMVSDLRNPPLSGTA 2693

Query: 779  RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR-----VPAYDADVTDKLQYRILS 833
             V I + D+ND+ P    F   F +     P    G      V A D D+   + Y+I+S
Sbjct: 2694 TVYIYLIDINDSPP---KFDASFLDQIISIPEDTPGNTIVTTVTATDDDLNSNINYQIVS 2750



 Score =  200 bits (488), Expect = 4e-49
 Identities = 156/516 (30%), Positives = 249/516 (48%), Gaps = 24/516 (4%)

Query: 373  VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432
            V++ E + P   V TL ATD D D  + Y++     R  F+I    G+  +     LD++
Sbjct: 523  VKVTEGQSPSILVFTLNATDPDGDP-ITYDLFDDEARSIFTINQFTGQ--LYALPGLDYE 579

Query: 433  Q-ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491
                + ++TVS TD         + + ITD N+ AP F N P    VFE+A  G+ +  V
Sbjct: 580  TLGNQVIITVSVTDGINDPVPQTIYVRITDVNDIAPTFTNLPNITYVFENATFGSELYQV 639

Query: 492  SATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTV 551
              TD D      +TYS+S    +   +  +  F I    G I     L+ E +  Y +TV
Sbjct: 640  ITTDEDTFYGGFVTYSISLVTPSTPGSAPNNYFSIGETDGIIQLATSLNYEEIQQYFVTV 699

Query: 552  TARDGGV--PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
             ARD G    SLS T  + +SV+++ D  PVF    Y   I E   VG++V  + ATD D
Sbjct: 700  VARDYGTGDTSLSSTATLTVSVLNIQDTNPVFINTPYDVTIPETLPVGSTVQTITATDPD 759

Query: 610  VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES---VATHDLKAVAIDGGTPP 666
                  I Y L   D  +G FVID  +G+I  N  +DR++    AT+ L   A++  +  
Sbjct: 760  SNDGNIITYNLVVSD-SQGYFVIDQTTGIITVNSQMDRDNPVLPATYPLIVSAVETSSGG 818

Query: 667  QS-STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG-EIRAHDPDEGPNAVVHY 724
             S + V  ++ +   ND PP+F+ +  +  I E++ + + +   I  +D D   ++ V  
Sbjct: 819  VSFAQVSFNVTVSPANDEPPMFDQNSYSASIPESASVNSQLPITITVNDGDLITDSTVTV 878

Query: 725  SIKGGDDSNSFSLETRQ--GSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEI 782
            S++ G +S  F +   Q  GS   +++    LD+E+  ++Y L ++A      +   + +
Sbjct: 879  SLQNG-NSVPFRVSPTQVVGSGTVDILITQPLDFEN-NQQYTLQLQAVDGDGQDIAPLMV 936

Query: 783  LVTDVNDNAPVMKDFQIIFNNYKDCF----PVGPF-GRVPAYDADVTDK--LQYRILSGN 835
             VTDVNDN PV  + + I N Y+         G F  +V   DAD      + Y I+SGN
Sbjct: 937  TVTDVNDNNPVFIN-RPIDNIYRGSINENDQTGTFIVQVSTTDADSGSNAAVTYSIISGN 995

Query: 836  NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
              N+  +N T+G++T +  L  N P+  T+ V  T+
Sbjct: 996  INNVFTINPTSGAITNTQILGPNTPQTYTLSVRATN 1031



 Score =  190 bits (462), Expect = 6e-46
 Identities = 170/576 (29%), Positives = 258/576 (44%), Gaps = 68/576 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTADT 69
            + V D NDH+P F   QY  +V E    GT V  +   D D + +  ++ YTI  +T + 
Sbjct: 3548 VTVTDANDHNPTFVPDQYSLTVTENEPPGTQVGVVITIDGDTLPEYTDIIYTI--LTGNG 3605

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            L                   F I+  +G + T   LDREK + Y + + A +   PV   
Sbjct: 3606 LGN-----------------FTINSTTGIITTATILDREKTSEYVLTIGAEN---PVGGT 3645

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             + TAT+ + + D NDN P F E  YT +V      T N ++  + A D D G N  + Y
Sbjct: 3646 -TGTATVSIIVRDVNDNTPTFEENPYTSTV------TTNTLLVDVHANDPDEGGNGIVIY 3698

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             I+ GN   +F+ID+ +G ++LV  L+ + +R+Y LV+   D G+P   + T + + I  
Sbjct: 3699 EIVSGNEDNRFTIDNRTGVITLVNPLESQLIRNYTLVVIGHDLGNPQLQSNTTVDLRINY 3758

Query: 250  VNDNAPRFYTSLFQES---VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK-DYTGNV 305
            +  NAP  +    Q S   ++EN P+G  I+   A D D G N  + Y++    DY+   
Sbjct: 3759 LGLNAPPSFVRPNQGSTVFITENNPLGLLIINAFAVDDDVGANGVVDYSILPNFDYSD-- 3816

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
                TIDP +G +      DRE +  Y L V ATD GDP  S ++T              
Sbjct: 3817 ---FTIDPVTGDITILVSADREIKDSYTLTVVATDRGDPNLSTSSTFVIRVLDENDNNPA 3873

Query: 366  FM-------PGQYEVELAEDEPPGTPVVTLT-ATDAD--EDNRLHYEITGGNTRGRFSIT 415
            F        P    + + E+      V T+  A D D   + ++ Y I      G F I 
Sbjct: 3874 FPRPDGMNNPIVLNLNVFENANISDLVGTVDGAIDLDLGANGQIFYHIVDSTVGGIFVIN 3933

Query: 416  SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM-----------VQINITDANN 464
            S  G  ++TV   LD +    + + + AT+    + T             V+I + D N+
Sbjct: 3934 STTG--VVTVNGTLDREDIGVHTIYILATNDATYNGTGPYNVLDNISLKEVKITLLDIND 3991

Query: 465  YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS----EISNEAVAHH 520
             AP F +   +A +  D  +G TV+ V+  D D G N  I YSL+S        E +A  
Sbjct: 3992 NAPRFTSTVISACIPFDISLGMTVVSVAVVDLDGGTNLGIAYSLNSIQFINSEGERLAAI 4051

Query: 521  DQQFVINPQTGAITTNKLLDRETMSGYL-LTVTARD 555
            +  F IN +TG I TN+      + GY  + V A D
Sbjct: 4052 N-AFTINSETGQIVTNQRFGEAYLQGYFDIVVQATD 4086



 Score =  167 bits (405), Expect = 5e-39
 Identities = 146/515 (28%), Positives = 234/515 (45%), Gaps = 43/515 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V+D     P+F + +Y A+V E  ++ T V  + AT    G  A + Y I+       
Sbjct: 1676 VTVVDDTVTIPIFTLSRYPATVIENVNADTPVTRVSATLN--GNPAGITYAID----PNA 1729

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +P             V ++F+ID  +G + T  ++DRE    Y   V A  + S      
Sbjct: 1730 SP------------AVLEIFKIDENTGHITTEGAIDREVEDFYAFTVFAYHEDSVA---- 1773

Query: 131  SSTATIHVNIIDDNDNYPQF-SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
              + ++ VNI+D+NDN P+F +     VSV E+     N  +   +ATD D G N+ + +
Sbjct: 1774 PGSTSVWVNILDENDNPPEFITVPPSPVSVRENTG--GNVPVGLFRATDPDAGINAQMTF 1831

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            +I G  +       + +G  ++V T  LD E+   Y+L + A DGG+PS S++  L I +
Sbjct: 1832 SISGAGSNFFNVFQTANGGGTIVVTSPLDRERQDFYQLTVTATDGGNPSLSSSFPLNITV 1891

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
             DVNDN P +  ++++ S++EN      I+ V   D D   +    Y++   D  G  ++
Sbjct: 1892 TDVNDNYPIWTRNVYEGSINENNFTSNPIITVMVNDLDLPSSNNFEYSIIAGDPMGMFEI 1951

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATD-GGDPPRSATATXXXXXXXXXXXXXXF 366
                   +G +  S  LDRE Q  YQL +   D    PP   T                F
Sbjct: 1952 -----NSNGEITVSSLLDREQQETYQLTIELIDQTNSPPARTTTLAIITVGDENDNTPIF 2006

Query: 367  MPGQYEVELAE-DEPPGTPVVTLTATDADED-NR-LHYEITGGNTRGRFSITSQNGRGLI 423
                  V++ E       PV  LTA D D   NR + Y I     +  F I  +   G+I
Sbjct: 2007 AETVIRVDVTEGPSSQNIPVYMLTANDIDLGLNRDIIYAIGSQQPQSHFQINPET--GMI 2064

Query: 424  TVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPY-TASVF 479
            +    LD++    Y L V+ATD      R+ TA V +++ D N+ AP+F    Y   SV 
Sbjct: 2065 STTTALDWETISEYTLIVTATDQSPTEPRTGTATVIVSVNDINDGAPMFVRDVYGPYSVV 2124

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
            E+    + +    ATD+D G+   +TYS+   +++
Sbjct: 2125 EEVS-NSYIDSFQATDTDQGLAGTVTYSVIVSVND 2158



 Score = 92.7 bits (220), Expect = 1e-16
 Identities = 137/521 (26%), Positives = 225/521 (43%), Gaps = 42/521 (8%)

Query: 378  DEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435
            +E   + + +  ATD D+     + Y + G  +   F I  Q G   I   + LD++   
Sbjct: 2178 EEVSNSYIDSFQATDTDQGLAGMVTYSVIGQYS-DLFFIQPQTGVLTIRPDRALDYETIT 2236

Query: 436  RYVLTVSATDSG-----GRSDTAMVQINITDANNYAPVFE-NAPYTASVFEDAPIGTTVL 489
             + +TV ATD G         T ++ I    A +Y  + E N    A+   +  + ++ L
Sbjct: 2237 EFNITVVATDMGVPALSSSPQTGVLTIRPDRALDYETITEFNITVVATDMGNPALSSSTL 2296

Query: 490  ----VVSATD-SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
                V++  D + +      T +LS  IS  ++A+  +    +         ++ D  T 
Sbjct: 2297 VGINVININDHTPIFEGIPYTITLSKNISAGSLAYVVRATDDDAGIFGEVRYQITDGNTD 2356

Query: 545  SGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
            + + +  T    G     +  T V I+V+++ND+ P+F+   YT  + ++   G+    V
Sbjct: 2357 NIFRIDQTIDSMGATEEKTGQTLVGINVININDHTPIFEGIPYTITLSKNISAGSLAYVV 2416

Query: 604  GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
             ATD D G+ G + Y++      +  F ID  +G  +T +   +  + T   + V     
Sbjct: 2417 RATDDDAGIFGEVRYQI-TDGNTDNIFRIDQTTG--QTGEVFVQGLLETGTYRLVVEARD 2473

Query: 664  TP---PQS--STVIVHIKIEDINDSPPVFE-SDCLTFYISENSPIG---TTIGEIRAHDP 714
            TP   P S  S+  + I + DI D  P F  S   T  + EN+P+G   T I  IRA + 
Sbjct: 2474 TPGDIPSSRASSTTLTIVVTDIGDLAPTFPGSSLFTGNVFENAPVGQPITMIPPIRAINS 2533

Query: 715  DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL-VIRAASPP 773
            D     V  Y+I  G DS +F +        A +     LD E+ +  YE  VI   S  
Sbjct: 2534 DATGQLV--YTIT-GPDSQTFMINQL----SAGIQVNGPLDRET-KDFYEFGVIVTDSMG 2585

Query: 774  LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDKLQYRIL 832
            L     V I V DVND AP   D    F    +  P G + G V AYD D  D + + I 
Sbjct: 2586 LTAMGTVHINVLDVNDFAPAFNDSVYNF-TIPENSPGGYYVGGVSAYDLD-GDNVNFFIQ 2643

Query: 833  SGNNANLILLNETTGSMTLSP--QLNTNVPKLATMEVSVTD 871
            +G   +   +  T+G++T++P   L+       T+ V V+D
Sbjct: 2644 TGGE-DKFDIGGTSGTITVTPGAVLDREEKPFYTLTVMVSD 2683



 Score = 38.3 bits (85), Expect = 3.0
 Identities = 33/136 (24%), Positives = 62/136 (45%), Gaps = 14/136 (10%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I +LD ND++P F      A +    S G TV+++   D D G N  + Y++  +    
Sbjct: 3983 KITLLDINDNAPRFTSTVISACIPFDISLGMTVVSVAVVDLDGGTNLGIAYSLNSI--QF 4040

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARY-TVLVKATDQASPVSD 128
            +N E              + F I+  +G ++T        +  Y  ++V+ATD    V+ 
Sbjct: 4041 INSEGERLAAI-------NAFTINSETGQIVTNQRFGEAYLQGYFDIVVQATD----VNT 4089

Query: 129  RLSSTATIHVNIIDDN 144
               + A+I + I+++N
Sbjct: 4090 GQFAVASIRLCILNNN 4105


>UniRef50_Q9NYQ8 Cluster: Protocadherin Fat 2 precursor; n=19;
            Amniota|Rep: Protocadherin Fat 2 precursor - Homo sapiens
            (Human)
          Length = 4349

 Score =  339 bits (833), Expect = 7e-91
 Identities = 230/720 (31%), Positives = 349/720 (48%), Gaps = 47/720 (6%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            Q+++ D ND++P F  ++Y  SV E +  G  V TLK  D DI +    + T  +   D 
Sbjct: 2893 QVSITDENDNAPRFASEEYRGSVVENSEPGELVATLKTLDADISEQNR-QVTCYITEGDP 2951

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            L               V D +RI  R        +LDRE  A+Y + V A+D       +
Sbjct: 2952 LGQ--------FGISQVGDEWRISSRK-------TLDREHTAKYLLRVTASD------GK 2990

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
              ++ T+ + ++D NDN PQ S+  YT  V ED  V     I K+ ATD D   N+ I Y
Sbjct: 2991 FQASVTVEIFVLDVNDNSPQCSQLLYTGKVHED--VFPGHFILKVSATDLDTDTNAQITY 3048

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            ++ G     +F +D  +G+++ +  LD E+   + LV +A DGG   RS    + +++ D
Sbjct: 3049 SLHGPGAH-EFKLDPHTGELTTLTALDRERKDVFNLVAKATDGGG--RSCQADITLHVED 3105

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            VNDNAPRF+ S    +V +N  +   +  V A D D+G NA++ Y++ D     + +   
Sbjct: 3106 VNDNAPRFFPSHCAVAVFDNTTVKTPVAVVFARDPDQGANAQVVYSLPD-----SAEGHF 3160

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSATATXXXXXXXXXXXXXXFMP 368
            +ID  +G +     L    QA  +L V A+D G P P S   T              F+ 
Sbjct: 3161 SIDATTGVIRLEKPLQVRPQAPLELTVRASDLGTPIPLSTLGTVTVSVVGLEDYLPVFLN 3220

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
             ++ V++ ED PPGT V+ L         +  Y +  GN +GRF + ++   G++ V   
Sbjct: 3221 TEHSVQVPEDAPPGTEVLQLATLTRPGAEKTGYRVVSGNEQGRFRLDART--GILYVNAS 3278

Query: 429  LDFKQERRYVLTV--SATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
            LDF+   +Y L++  S   S   SD   V +NITD N + P F   PY+  V E+A +G 
Sbjct: 3279 LDFETSPKYFLSIECSRKSSSSLSDVTTVMVNITDVNEHRPQFPQDPYSTRVLENALVGD 3338

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
             +L VSATD D  +N+ ITYSL   I    + H    F I+P+ G +   K LDRE  S 
Sbjct: 3339 VILTVSATDEDGPLNSDITYSL---IGGNQLGH----FTIHPKKGELQVAKALDREQASS 3391

Query: 547  YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
            Y L + A D G P L + TD+ I V DVNDN P F Q  Y+  + E++ +G+ V Q+  +
Sbjct: 3392 YSLKLRATDSGQPPLHEDTDIAIQVADVNDNPPRFFQLNYSTTVQENSPIGSKVLQLILS 3451

Query: 607  DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
            D D   NG  +     K     +F + P  G + T + L R +   + L+  A D G PP
Sbjct: 3452 DPDSPENGPPYSFRITKGNNGSAFRVTP-DGWLVTAEGLSRRAQEWYQLQIQASDSGIPP 3510

Query: 667  QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
             SS   V + + + +   P      +   + E+   G  +G+I A D D  P   + YS+
Sbjct: 3511 LSSLTSVRVHVTEQSHYAPSALPLEIFITVGEDEFQGGMVGKIHATDRD--PQDTLTYSL 3568



 Score =  312 bits (767), Expect = 7e-83
 Identities = 260/881 (29%), Positives = 401/881 (45%), Gaps = 58/881 (6%)

Query: 3    VPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
            V FC   +I + D ND+ P F+  +Y  S++   S  + V+ + A D D G+NA+V Y++
Sbjct: 2566 VAFCT-VKIILTDENDNPPQFKASEYTVSIQSNVSKDSPVIQVLAYDADEGQNADVTYSV 2624

Query: 63   ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122
                    NPED           V+DV  I+  +G +  + SL   +       +KA D 
Sbjct: 2625 --------NPED----------LVKDVIEINPVTGVVKVKDSLVGLENQTLDFFIKAQDG 2666

Query: 123  ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA-DV 181
              P     +S   + + ++    + P+FSE  YT S  ED+   +   I  +KA  A D 
Sbjct: 2667 GPP---HWNSLVPVRLQVVPKKVSLPKFSEPLYTFSAPEDL--PEGSEIGIVKAVAAQDP 2721

Query: 182  GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
               S +R      N    FS+D  +G + + K +D+E  + Y++ + A    +    +  
Sbjct: 2722 VIYSLVRGTTPESNKDGVFSLDPDTGVIKVRKPMDHESTKLYQIDVMAHCLQNTDVVSLV 2781

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
             + I + DVNDN P F    ++  ++EN+P+G S+++V A D D G + +++Y ++  D 
Sbjct: 2782 SVNIQVGDVNDNRPVFEADPYKAVLTENMPVGTSVIQVTAIDKDTGRDGQVSYRLS-ADP 2840

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR-SATATXXXXXXXXX 360
              NV     ID  SGW+ T  +LD ET   Y   V A D G   + S+ A          
Sbjct: 2841 GSNVHELFAIDSESGWITTLQELDCETCQTYHFHVVAYDHGQTIQLSSQALVQVSITDEN 2900

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNR-LHYEITGGNTRGRFSITSQ 417
                 F   +Y   + E+  PG  V TL   DAD  E NR +   IT G+  G+F I+  
Sbjct: 2901 DNAPRFASEEYRGSVVENSEPGELVATLKTLDADISEQNRQVTCYITEGDPLGQFGISQV 2960

Query: 418  NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTAS 477
                 I+  + LD +   +Y+L V+A+D G    +  V+I + D N+ +P      YT  
Sbjct: 2961 GDEWRISSRKTLDREHTAKYLLRVTASD-GKFQASVTVEIFVLDVNDNSPQCSQLLYTGK 3019

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            V ED   G  +L VSATD D   NAQITYSL    ++E        F ++P TG +TT  
Sbjct: 3020 VHEDVFPGHFILKVSATDLDTDTNAQITYSLHGPGAHE--------FKLDPHTGELTTLT 3071

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
             LDRE    + L   A DGG    S   D+ + V DVNDN P F        + ++  V 
Sbjct: 3072 ALDRERKDVFNLVAKATDGG--GRSCQADITLHVEDVNDNAPRFFPSHCAVAVFDNTTVK 3129

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
            T V+ V A D D G N ++ Y L   D  EG F ID  +GVIR  K L     A  +L  
Sbjct: 3130 TPVAVVFARDPDQGANAQVVYSL--PDSAEGHFSIDATTGVIRLEKPLQVRPQAPLELTV 3187

Query: 658  VAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
             A D GTP P S+   V + +  + D  PVF +   +  + E++P GT + ++       
Sbjct: 3188 RASDLGTPIPLSTLGTVTVSVVGLEDYLPVFLNTEHSVQVPEDAPPGTEVLQLATL---T 3244

Query: 717  GPNA-VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI---RAASP 772
             P A    Y +  G++   F L+ R G     L     LD+E+   KY L I   R +S 
Sbjct: 3245 RPGAEKTGYRVVSGNEQGRFRLDARTGI----LYVNASLDFET-SPKYFLSIECSRKSSS 3299

Query: 773  PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYR 830
             L +   V + +TDVN++ P            ++         V A D D  +   + Y 
Sbjct: 3300 SLSDVTTVMVNITDVNEHRPQFPQDPYSTRVLENALVGDVILTVSATDEDGPLNSDITYS 3359

Query: 831  ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            ++ GN      ++   G + ++  L+       ++++  TD
Sbjct: 3360 LIGGNQLGHFTIHPKKGELQVAKALDREQASSYSLKLRATD 3400



 Score =  298 bits (731), Expect = 2e-78
 Identities = 261/888 (29%), Positives = 400/888 (45%), Gaps = 75/888 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEA-SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++    N ++P FE    ++  V E     T +  L ATD D G N ++ Y I    AD 
Sbjct: 702  LSTYQINHYTPQFEDHFPQSIDVLESVPINTPLARLAATDPDAGFNGKLVYVI----ADG 757

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             N E                F I+  +G L   A LD E    Y + V   D  +P   +
Sbjct: 758  -NEEGC--------------FDIELETGLLTVAAPLDYEATNFYILNVTVYDLGTP---Q 799

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             SS   + VN+ D NDN P+F    Y +++ ED  V     IA++   DAD   N  +RY
Sbjct: 800  KSSWKLLTVNVKDWNDNAPRFPPGGYQLTISEDTEV--GTTIAELTTKDADSEDNGRVRY 857

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS--NTTQLLINI 247
             ++    +  FS+  L+G++ +   LD E    Y L + A+D  S      + T L+I +
Sbjct: 858  TLLSPTEK--FSLHPLTGELVVTGHLDRESEPRYILKVEARDQPSKGHQLFSVTDLIITL 915

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY-TGNVD 306
             DVNDN+P+  T   +  V E++P G  +  + A D D G   E+ Y + D  + T  VD
Sbjct: 916  EDVNDNSPQCITEHNRLKVPEDLPPGTVLTFLDASDPDLGPAGEVRYVLMDGAHGTFRVD 975

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX-- 364
            L       +G +    +LD E +A Y L + A+DGG P    T                 
Sbjct: 976  L------MTGALILERELDFERRAGYNLSLWASDGGRPLARRTLCHVEVIVLDVNENLHP 1029

Query: 365  -XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRG 421
              F    ++ ++ E+ P GT V+ + A D D   D  L Y +  G     FSI      G
Sbjct: 1030 PHFASFVHQGQVQENSPSGTQVIVVAAQDDDSGLDGELQYFLRAGTGLAAFSINQDT--G 1087

Query: 422  LITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVF 479
            +I    PLD +    Y LTV A D G    S    V I +TDAN+  P    A +  S+ 
Sbjct: 1088 MIQTLAPLDREFASYYWLTVLAVDRGSVPLSSVTEVYIEVTDANDNPPQMSQAVFYPSIQ 1147

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
            EDAP+GT+VL + A D D     ++T++++S        ++   F+I+P TG ++T + L
Sbjct: 1148 EDAPVGTSVLQLDAWDPDSSSKGKLTFNITS-------GNYMGFFMIHPVTGLLSTAQQL 1200

Query: 540  DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME--DALVG 597
            DRE    ++L VT  D G PSL  T+ V + ++DVNDN P+F  +L+   + E    +  
Sbjct: 1201 DRENKDEHILEVTVLDNGEPSLKSTSRVVVGILDVNDNPPIFSHKLFNVRLPERLSPVSP 1260

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
              V ++ A+D D GLNGR+ Y ++  D  E +F ID  +GV+ +N            +KA
Sbjct: 1261 GPVYRLVASDLDEGLNGRVTYSIE--DSYEEAFSIDLVTGVVSSNSTFTAGEYNILTIKA 1318

Query: 658  VAIDGGTPPQSSTVIVHIK---IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
               D G PP S++V +HI+       +  P  F+    +F + E  P+   +G I     
Sbjct: 1319 T--DSGQPPLSASVRLHIEWIPWPRPSSIPLAFDETYYSFTVMETDPVNHMVGVISV--- 1373

Query: 715  DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL 774
             EG   +  ++I GGD    F +E   GS    +V    LD    R  Y L +       
Sbjct: 1374 -EGRPGLFWFNISGGDKDMDFDIEKTTGS----IVIARPLDTRR-RSNYNLTVEVTDGSR 1427

Query: 775  WNDVRVEI-LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILS 833
                +V I ++ ++N + P   + +      +D  P     RV A D D    L Y I  
Sbjct: 1428 TIATQVHIFMIANINHHRPQFLETRYEVRVPQDTVPGVELLRVQAIDQDKGKSLIYTIHG 1487

Query: 834  G---NNANLILLNETTGSMTLSPQLNT-NVPKLATMEVSVTDGVNEIK 877
                 +A+L  L+ ++G +    +L+  + P   T+ V V D    IK
Sbjct: 1488 SQDPGSASLFQLDPSSGVLVTVGKLDLGSGPSQHTLTVMVRDQEIPIK 1535



 Score =  279 bits (683), Expect = 1e-72
 Identities = 238/799 (29%), Positives = 368/799 (46%), Gaps = 69/799 (8%)

Query: 8    HQQINVLDCND--HSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELV 65
            H ++ VLD N+  H P F    ++  V+E + SGT V+ + A D D G + E++Y +   
Sbjct: 1015 HVEVIVLDVNENLHPPHFASFVHQGQVQENSPSGTQVIVVAAQDDDSGLDGELQYFLRAG 1074

Query: 66   TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125
            T                       F I+  +G + T A LDRE  + Y + V A D+ S 
Sbjct: 1075 TG-------------------LAAFSINQDTGMIQTLAPLDREFASYYWLTVLAVDRGSV 1115

Query: 126  VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
                LSS   +++ + D NDN PQ S+  +  S+ ED  V  +  + ++ A D D  +  
Sbjct: 1116 ---PLSSVTEVYIEVTDANDNPPQMSQAVFYPSIQEDAPVGTS--VLQLDAWDPDSSSKG 1170

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
             + + I  GN    F I  ++G +S  + LD E    + L +   D G PS  +T+++++
Sbjct: 1171 KLTFNITSGNYMGFFMIHPVTGLLSTAQQLDRENKDEHILEVTVLDNGEPSLKSTSRVVV 1230

Query: 246  NIRDVNDNAPRFYTSLFQESVSENV-PIGYS-IVRVQAYDADEGVNAELTYTMTDKDYTG 303
             I DVNDN P F   LF   + E + P+    + R+ A D DEG+N  +TY++ D     
Sbjct: 1231 GILDVNDNPPIFSHKLFNVRLPERLSPVSPGPVYRLVASDLDEGLNGRVTYSIED----- 1285

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLL-VTATDGGDPPRSATATXXXXXX---XX 359
            + +   +ID  +G V ++      T  +Y +L + ATD G PP SA+             
Sbjct: 1286 SYEEAFSIDLVTGVVSSNSTF---TAGEYNILTIKATDSGQPPLSASVRLHIEWIPWPRP 1342

Query: 360  XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG 419
                  F    Y   + E +P    V  ++           + I+GG+    F I  +  
Sbjct: 1343 SSIPLAFDETYYSFTVMETDPVNHMVGVISV--EGRPGLFWFNISGGDKDMDFDI--EKT 1398

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQI-NITDANNYAPVFENAPYTASV 478
             G I +A+PLD ++   Y LTV  TD G R+    V I  I + N++ P F    Y   V
Sbjct: 1399 TGSIVIARPLDTRRRSNYNLTVEVTD-GSRTIATQVHIFMIANINHHRPQFLETRYEVRV 1457

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             +D   G  +L V A D D G +   T   S +  + ++      F ++P +G + T   
Sbjct: 1458 PQDTVPGVELLRVQAIDQDKGKSLIYTIHGSQDPGSASL------FQLDPSSGVLVTVGK 1511

Query: 539  LDRET-MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
            LD  +  S + LTV  RD  +P   +   V I V D N + P F Q  Y A++ +    G
Sbjct: 1512 LDLGSGPSQHTLTVMVRDQEIPIKRNFVWVTIHVEDGNLHPPRFTQLHYEASVPDTIAPG 1571

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
            T + QV A DAD G+N  +HY L  K   EG F I+   G+I   + LD+ + A H L  
Sbjct: 1572 TELLQVRAMDADRGVNAEVHYSL-LKGNSEGFFNINALLGIITLAQKLDQANHAPHTLTV 1630

Query: 658  VAIDGGTPP--QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
             A D G+P     +TVI+H+   D   S P+F        I E+ P+G+ I  + A  P 
Sbjct: 1631 KAEDQGSPQWHDLATVIIHVYPSD--RSAPIFSKSEYFVEIPESIPVGSPILLVSAMSPS 1688

Query: 716  EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS-PPL 774
            E     V Y ++ G+    FS+ +  G     + T   LD+E     Y+L IR ++    
Sbjct: 1689 E-----VTYELREGNKDGVFSMNSYSGL----ISTQKKLDHEK-ISSYQLKIRGSNMAGA 1738

Query: 775  WNDVRVEILVTDVNDNAPV 793
            + DV V + + D NDNAP+
Sbjct: 1739 FTDVMVVVDIIDENDNAPM 1757



 Score =  273 bits (670), Expect = 4e-71
 Identities = 253/897 (28%), Positives = 409/897 (45%), Gaps = 70/897 (7%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++++ D ND+ P F+   Y   +++G   G  +  + ATD+D+G N  V Y         
Sbjct: 2057 RVSIEDVNDNPPKFKHLPYYTIIQDGTEPGDVLFQVSATDEDLGTNGAVTYEFA------ 2110

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
               ED               FRID   G +  +   D + + +Y + V A D  +P    
Sbjct: 2111 ---EDYTY------------FRIDPYLGDISLKKPFDYQALNKYHLKVIARDGGTP---S 2152

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            L S   + V +   N + P F    Y V V E+I++   P++     T A       + Y
Sbjct: 2153 LQSEEEVLVTV--RNKSNPLFQSPYYKVRVPENITLY-TPILH----TQARSPEGLRLIY 2205

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             I+     M F+ D  +G +++   LDYE    +   +RA D    S S  T  ++ + D
Sbjct: 2206 NIVEEEPLMLFTTDFKTGVLTVTGPLDYESKTKHVFTVRATDTALGSFSEATVEVL-VED 2264

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            VNDN P F   ++  S+SE +P    ++++ A D D G N +++Y + +     +V    
Sbjct: 2265 VNDNPPTFSQLVYTTSISEGLPAQTPVIQLLASDQDSGRNRDVSYQIVEDG--SDVSKFF 2322

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             I+  +G + T  +LD E Q  + + V A D GDPP +                  F   
Sbjct: 2323 QINGSTGEMSTVQELDYEAQQHFHVKVRAMDKGDPPLTGETLVVVNVSDINDNPPEFRQP 2382

Query: 370  QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
            QYE  ++E    G  V+ + A D D  + +RL Y I  GN    F I S +G  +I++  
Sbjct: 2383 QYEANVSELATCGHLVLKVQAIDPDSRDTSRLEYLILSGNQDRHFFINSSSG--IISMFN 2440

Query: 428  PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
                  +  Y L V A+D   R+ T  V IN T+AN Y+P F+   Y A + E+A +GT 
Sbjct: 2441 LCKKHLDSSYNLRVGASDGVFRA-TVPVYINTTNANKYSPEFQQHLYEAELAENAMVGTK 2499

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
            V+ + A D D G    I Y++ +++++E       +F INP  G I T + LDRE  +  
Sbjct: 2500 VIDLLAIDKDSGPYGTIDYTIINKLASE-------KFSINPN-GQIATLQKLDRENSTER 2551

Query: 548  LLT--VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
            ++   V ARDGG      T  V+I + D NDN P FK   YT +I  +    + V QV A
Sbjct: 2552 VIAIKVMARDGGGRVAFCT--VKIILTDENDNPPQFKASEYTVSIQSNVSKDSPVIQVLA 2609

Query: 606  TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
             DAD G N  + Y ++P+D  +    I+P +GV++   +L      T D    A DGG P
Sbjct: 2610 YDADEGQNADVTYSVNPEDLVKDVIEINPVTGVVKVKDSLVGLENQTLDFFIKAQDGGPP 2669

Query: 666  PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
              +S V V +++     S P F     TF   E+ P G+ IG ++A       + V++  
Sbjct: 2670 HWNSLVPVRLQVVPKKVSLPKFSEPLYTFSAPEDLPEGSEIGIVKA---VAAQDPVIYSL 2726

Query: 726  IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEI 782
            ++G    ++         D   +     +D+ES  K Y++ + A    +  + + V V I
Sbjct: 2727 VRGTTPESNKDGVFSLDPDTGVIKVRKPMDHES-TKLYQIDVMAHCLQNTDVVSLVSVNI 2785

Query: 783  LVTDVNDNAPVMK--DFQIIFNNYKDCFPVG-PFGRVPAYDADV--TDKLQYRILS--GN 835
             V DVNDN PV +   ++ +     +  PVG    +V A D D     ++ YR+ +  G+
Sbjct: 2786 QVGDVNDNRPVFEADPYKAVLT---ENMPVGTSVIQVTAIDKDTGRDGQVSYRLSADPGS 2842

Query: 836  NAN-LILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL-ITEE 890
            N + L  ++  +G +T   +L+    +     V   D    I+   Q  V++ IT+E
Sbjct: 2843 NVHELFAIDSESGWITTLQELDCETCQTYHFHVVAYDHGQTIQLSSQALVQVSITDE 2899



 Score =  271 bits (664), Expect = 2e-70
 Identities = 253/902 (28%), Positives = 409/902 (45%), Gaps = 60/902 (6%)

Query: 89   VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
            VF +D  +G +  R  +D E    Y + V A       +D + S  ++++ + D NDN P
Sbjct: 2739 VFSLDPDTGVIKVRKPMDHESTKLYQIDVMA--HCLQNTD-VVSLVSVNIQVGDVNDNRP 2795

Query: 149  QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII---GGNTQMQFSIDSL 205
             F    Y   + E++ V  +  + ++ A D D G +  + Y +    G N    F+IDS 
Sbjct: 2796 VFEADPYKAVLTENMPVGTS--VIQVTAIDKDTGRDGQVSYRLSADPGSNVHELFAIDSE 2853

Query: 206  SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIRDVNDNAPRFYTSLFQE 264
            SG ++ ++ LD E  ++Y   + A D G   + ++  L+ ++I D NDNAPRF +  ++ 
Sbjct: 2854 SGWITTLQELDCETCQTYHFHVVAYDHGQTIQLSSQALVQVSITDENDNAPRFASEEYRG 2913

Query: 265  SVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323
            SV EN   G  +  ++  DAD    N ++T  +T+ D  G   +    D    W  +S +
Sbjct: 2914 SVVENSEPGELVATLKTLDADISEQNRQVTCYITEGDPLGQFGISQVGDE---WRISSRK 2970

Query: 324  -LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382
             LDRE  AKY L VTA+DG      A+ T                   Y  ++ ED  PG
Sbjct: 2971 TLDREHTAKYLLRVTASDG---KFQASVTVEIFVLDVNDNSPQCSQLLYTGKVHEDVFPG 3027

Query: 383  TPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440
              ++ ++ATD D D   ++ Y + G      F +    G   +T    LD +++  + L 
Sbjct: 3028 HFILKVSATDLDTDTNAQITYSLHGPGAH-EFKLDPHTGE--LTTLTALDRERKDVFNLV 3084

Query: 441  VSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
              ATD GGRS  A + +++ D N+ AP F  +    +VF++  + T V VV A D D G 
Sbjct: 3085 AKATDGGGRSCQADITLHVEDVNDNAPRFFPSHCAVAVFDNTTVKTPVAVVFARDPDQGA 3144

Query: 501  NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP- 559
            NAQ+ YSL     + A  H    F I+  TG I   K L     +   LTV A D G P 
Sbjct: 3145 NAQVVYSLP----DSAEGH----FSIDATTGVIRLEKPLQVRPQAPLELTVRASDLGTPI 3196

Query: 560  SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619
             LS    V +SVV + D  PVF    ++  + EDA  GT V Q+ AT    G   +  Y 
Sbjct: 3197 PLSTLGTVTVSVVGLEDYLPVFLNTEHSVQVPEDAPPGTEVLQL-ATLTRPGAE-KTGYR 3254

Query: 620  LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679
            +     E+G F +D  +G++  N +LD E+   + L        +   S    V + I D
Sbjct: 3255 V-VSGNEQGRFRLDARTGILYVNASLDFETSPKYFLSIECSRKSSSSLSDVTTVMVNITD 3313

Query: 680  INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLET 739
            +N+  P F  D  +  + EN+ +G  I  + A D D   N+ + YS+ GG+    F++  
Sbjct: 3314 VNEHRPQFPQDPYSTRVLENALVGDVILTVSATDEDGPLNSDITYSLIGGNQLGHFTIHP 3373

Query: 740  RQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKD 796
            ++G    EL     LD E     Y L +RA     PPL  D  + I V DVNDN P  + 
Sbjct: 3374 KKG----ELQVAKALDREQ-ASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPP--RF 3426

Query: 797  FQIIFN-NYKDCFPVG-PFGRVPAYDADVTDK---LQYRILSGNNANLILLNETTGSMTL 851
            FQ+ ++   ++  P+G    ++   D D  +      +RI  GNN +   +    G +  
Sbjct: 3427 FQLNYSTTVQENSPIGSKVLQLILSDPDSPENGPPYSFRITKGNNGSAFRVT-PDGWLVT 3485

Query: 852  SPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLS 910
            +  L+    +   +++  +D G+  + ++  + V  +TE+       + L ++       
Sbjct: 3486 AEGLSRRAQEWYQLQIQASDSGIPPLSSLTSVRVH-VTEQSHYAPSALPL-EIFITVGED 3543

Query: 911  PLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVA-GDPSPH 969
               G  +  + A    P++ +     +++T      L   FS   PD ++  A G P  H
Sbjct: 3544 EFQGGMVGKIHATDRDPQDTLTYSLAEEET------LGRHFSVGAPDGKIIAAQGLPRGH 3597

Query: 970  YS 971
            YS
Sbjct: 3598 YS 3599



 Score =  259 bits (634), Expect = 9e-67
 Identities = 235/862 (27%), Positives = 377/862 (43%), Gaps = 71/862 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I + D ND+SP    +     V E    GT +  L A+D D+G   EV Y +        
Sbjct: 913  ITLEDVNDNSPQCITEHNRLKVPEDLPPGTVLTFLDASDPDLGPAGEVRYVL-------- 964

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               FR+D  +GAL+    LD E+ A Y + + A+D   P++ R 
Sbjct: 965  ------------MDGAHGTFRVDLMTGALILERELDFERRAGYNLSLWASDGGRPLARRT 1012

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
                 + V  +++N + P F+   +   V E+ S +   VI  + A D D G +  ++Y 
Sbjct: 1013 LCHVEVIVLDVNENLHPPHFASFVHQGQVQEN-SPSGTQVIV-VAAQDDDSGLDGELQYF 1070

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            +  G     FSI+  +G +  +  LD E    Y L + A D GS   S+ T++ I + D 
Sbjct: 1071 LRAGTGLAAFSINQDTGMIQTLAPLDREFASYYWLTVLAVDRGSVPLSSVTEVYIEVTDA 1130

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN P+   ++F  S+ E+ P+G S++++ A+D D     +LT+ +T  +Y G       
Sbjct: 1131 NDNPPQMSQAVFYPSIQEDAPVGTSVLQLDAWDPDSSSKGKLTFNITSGNYMGF----FM 1186

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            I P +G + T+ QLDRE + ++ L VT  D G+P   +T+               F    
Sbjct: 1187 IHPVTGLLSTAQQLDRENKDEHILEVTVLDNGEPSLKSTSRVVVGILDVNDNPPIFSHKL 1246

Query: 371  YEVELAEDEPPGT--PVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
            + V L E   P +  PV  L A+D DE  + R+ Y I        FSI    G     V+
Sbjct: 1247 FNVRLPERLSPVSPGPVYRLVASDLDEGLNGRVTYSIEDSYEEA-FSIDLVTG----VVS 1301

Query: 427  QPLDFKQERRYVLTVSATDSGGRSDTAMVQINI-----TDANNYAPVFENAPYTASVFED 481
                F      +LT+ ATDSG    +A V+++I        ++    F+   Y+ +V E 
Sbjct: 1302 SNSTFTAGEYNILTIKATDSGQPPLSASVRLHIEWIPWPRPSSIPLAFDETYYSFTVMET 1361

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
             P+   V V+S      G      +++S           D  F I   TG+I   + LD 
Sbjct: 1362 DPVNHMVGVISVE----GRPGLFWFNISG-------GDKDMDFDIEKTTGSIVIARPLDT 1410

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEI-SVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
               S Y LTV   DG   S +  T V I  + ++N + P F +  Y   + +D + G  +
Sbjct: 1411 RRRSNYNLTVEVTDG---SRTIATQVHIFMIANINHHRPQFLETRYEVRVPQDTVPGVEL 1467

Query: 601  SQVGATDADVG--LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES-VATHDLKA 657
             +V A D D G  L   IH   DP       F +DP+SGV+ T   LD  S  + H L  
Sbjct: 1468 LRVQAIDQDKGKSLIYTIHGSQDP--GSASLFQLDPSSGVLVTVGKLDLGSGPSQHTLTV 1525

Query: 658  VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
            +  D   P + + V V I +ED N  PP F        + +    GT + ++RA D D G
Sbjct: 1526 MVRDQEIPIKRNFVWVTIHVEDGNLHPPRFTQLHYEASVPDTIAPGTELLQVRAMDADRG 1585

Query: 718  PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA--ASPPLW 775
             NA VHYS+  G+    F++    G     ++T+     ++    + L ++A     P W
Sbjct: 1586 VNAEVHYSLLKGNSEGFFNINALLG-----IITLAQKLDQANHAPHTLTVKAEDQGSPQW 1640

Query: 776  NDVRVEILVTDVND-NAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSG 834
            +D+   I+    +D +AP+    +  F    +  PVG    +    A    ++ Y +  G
Sbjct: 1641 HDLATVIIHVYPSDRSAPIFSKSE-YFVEIPESIPVG--SPILLVSAMSPSEVTYELREG 1697

Query: 835  NNANLILLNETTGSMTLSPQLN 856
            N   +  +N  +G ++   +L+
Sbjct: 1698 NKDGVFSMNSYSGLISTQKKLD 1719



 Score =  254 bits (623), Expect = 2e-65
 Identities = 248/879 (28%), Positives = 394/879 (44%), Gaps = 86/879 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I+V D N H P F    YEASV +  + GT +L ++A D D G NAEV Y+  L+  ++ 
Sbjct: 1543 IHVEDGNLHPPRFTQLHYEASVPDTIAPGTELLQVRAMDADRGVNAEVHYS--LLKGNS- 1599

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                            +  F I+   G +     LD+   A +T+ VKA DQ SP   + 
Sbjct: 1600 ----------------EGFFNINALLGIITLAQKLDQANHAPHTLTVKAEDQGSP---QW 1640

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
               AT+ +++   + + P FS+  Y V + E I V  +P++           + S + Y 
Sbjct: 1641 HDLATVIIHVYPSDRSAPIFSKSEYFVEIPESIPV-GSPILL------VSAMSPSEVTYE 1693

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            +  GN    FS++S SG +S  K LD+E++ SY+L IR  +           ++++I D 
Sbjct: 1694 LREGNKDGVFSMNSYSGLISTQKKLDHEKISSYQLKIRGSN--MAGAFTDVMVVVDIIDE 1751

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVR--------VQAYDADEGVNAELTYTMTDKDYT 302
            NDNAP F  S F   +SE  P+ YS++         + A D+D+  N+ L Y + + +  
Sbjct: 1752 NDNAPMFLKSTFVGQISEAAPL-YSMIMDKNNNPFVIHASDSDKEANSLLVYKILEPEAL 1810

Query: 303  GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT--ATXXXXXXXXX 360
                    IDP  G +    ++D E+   +Q  V   D G P   A   A          
Sbjct: 1811 KF----FKIDPSMGTLTIVSEMDYESMPSFQFCVYVHDQGSPVLFAPRPAQVIIHVRDVN 1866

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420
                 F    YEV +     PG  ++ + A+D  ED+ ++Y I  GN     ++T     
Sbjct: 1867 DSPPRFSEQIYEVAIVGPIHPGMELLMVRASD--EDSEVNYSIKTGNADE--AVTIHPVT 1922

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
            G I+V  P      R+  LT+ A+D G   DTA+V+I++T   + +  F+   Y A+V E
Sbjct: 1923 GSISVLNPAFLGLSRK--LTIRASD-GLYQDTALVKISLTQVLDKSLQFDQDVYWAAVKE 1979

Query: 481  DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL-L 539
            +      ++++ A  +   +N  ++Y L   ++   + H  Q        G + T  +  
Sbjct: 1980 NLQDRKALVILGAQGNH--LNDTLSYFL---LNGTDMFHMVQS------AGVLQTRGVAF 2028

Query: 540  DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
            DRE    + L V  RD   P       V +S+ DVNDN P FK   Y   I +    G  
Sbjct: 2029 DREQQDTHELAVEVRDNRTPQRVAQGLVRVSIEDVNDNPPKFKHLPYYTIIQDGTEPGDV 2088

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
            + QV ATD D+G NG + YE      +   F IDP  G I   K  D +++  + LK +A
Sbjct: 2089 LFQVSATDEDLGTNGAVTYEF---AEDYTYFRIDPYLGDISLKKPFDYQALNKYHLKVIA 2145

Query: 660  IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
             DGGTP   S   V + +   N S P+F+S      + EN  + T I   +A  P EG  
Sbjct: 2146 RDGGTPSLQSEEEVLVTVR--NKSNPLFQSPYYKVRVPENITLYTPILHTQARSP-EGLR 2202

Query: 720  AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL--WND 777
             +  Y+I   +    F+ + + G     L     LDYES + K+   +RA    L  +++
Sbjct: 2203 LI--YNIVEEEPLMLFTTDFKTG----VLTVTGPLDYES-KTKHVFTVRATDTALGSFSE 2255

Query: 778  VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPAYDADV--TDKLQYRILSG 834
              VE+LV DVNDN P      +   +  +  P   P  ++ A D D      + Y+I+  
Sbjct: 2256 ATVEVLVEDVNDNPPTFSQL-VYTTSISEGLPAQTPVIQLLASDQDSGRNRDVSYQIVED 2314

Query: 835  NN--ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
             +  +    +N +TG M+   +L+    +   ++V   D
Sbjct: 2315 GSDVSKFFQINGSTGEMSTVQELDYEAQQHFHVKVRAMD 2353



 Score =  222 bits (542), Expect = 1e-55
 Identities = 161/528 (30%), Positives = 262/528 (49%), Gaps = 29/528 (5%)

Query: 373  VELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
            +++ E  P  TP+  L ATD D   + +L Y I  GN  G F I  + G  L+TVA PLD
Sbjct: 722  IDVLESVPINTPLARLAATDPDAGFNGKLVYVIADGNEEGCFDIELETG--LLTVAAPLD 779

Query: 431  FKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
            ++    Y+L V+  D G   +S   ++ +N+ D N+ AP F    Y  ++ ED  +GTT+
Sbjct: 780  YEATNFYILNVTVYDLGTPQKSSWKLLTVNVKDWNDNAPRFPPGGYQLTISEDTEVGTTI 839

Query: 489  LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
              ++  D+D   N ++ Y+L S           ++F ++P TG +     LDRE+   Y+
Sbjct: 840  AELTTKDADSEDNGRVRYTLLSP---------TEKFSLHPLTGELVVTGHLDRESEPRYI 890

Query: 549  LTVTARD--GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
            L V ARD       L   TD+ I++ DVNDN P    +     + ED   GT ++ + A+
Sbjct: 891  LKVEARDQPSKGHQLFSVTDLIITLEDVNDNSPQCITEHNRLKVPEDLPPGTVLTFLDAS 950

Query: 607  DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
            D D+G  G + Y L   D   G+F +D  +G +   + LD E  A ++L   A DGG P 
Sbjct: 951  DPDLGPAGEVRYVL--MDGAHGTFRVDLMTGALILERELDFERRAGYNLSLWASDGGRPL 1008

Query: 667  QSSTVI-VHIKIEDINDS--PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
               T+  V + + D+N++  PP F S      + ENSP GT +  + A D D G +  + 
Sbjct: 1009 ARRTLCHVEVIVLDVNENLHPPHFASFVHQGQVQENSPSGTQVIVVAAQDDDSGLDGELQ 1068

Query: 724  YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEIL 783
            Y ++ G    +FS+   Q +   + +  +D ++ S      L +   S PL +   V I 
Sbjct: 1069 YFLRAGTGLAAFSI--NQDTGMIQTLAPLDREFASYYWLTVLAVDRGSVPLSSVTEVYIE 1126

Query: 784  VTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTD--KLQYRILSGNNANLI 840
            VTD NDN P M    + + + ++  PVG    ++ A+D D +   KL + I SGN     
Sbjct: 1127 VTDANDNPPQMSQ-AVFYPSIQEDAPVGTSVLQLDAWDPDSSSKGKLTFNITSGNYMGFF 1185

Query: 841  LLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLI 887
            +++  TG ++ + QL+        +EV+V D G   +K+  ++ V ++
Sbjct: 1186 MIHPVTGLLSTAQQLDRENKDEHILEVTVLDNGEPSLKSTSRVVVGIL 1233



 Score =  187 bits (456), Expect = 3e-45
 Identities = 127/374 (33%), Positives = 184/374 (49%), Gaps = 16/374 (4%)

Query: 87   QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146
            Q  FR+D R+G L   ASLD E   +Y + ++ + ++S     LS   T+ VNI D N++
Sbjct: 3261 QGRFRLDARTGILYVNASLDFETSPKYFLSIECSRKSS---SSLSDVTTVMVNITDVNEH 3317

Query: 147  YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206
             PQF +  Y+  V E+  V D  VI  + ATD D   NS I Y++IGGN    F+I    
Sbjct: 3318 RPQFPQDPYSTRVLENALVGD--VILTVSATDEDGPLNSDITYSLIGGNQLGHFTIHPKK 3375

Query: 207  GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266
            G++ + K LD EQ  SY L +RA D G P     T + I + DVNDN PRF+   +  +V
Sbjct: 3376 GELQVAKALDREQASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPPRFFQLNYSTTV 3435

Query: 267  SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326
             EN PIG  ++++   D D   N    Y+   +   GN      + P  GW+ T+  L R
Sbjct: 3436 QENSPIGSKVLQLILSDPDSPENGP-PYSF--RITKGNNGSAFRVTP-DGWLVTAEGLSR 3491

Query: 327  ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386
              Q  YQL + A+D G PP S+  +               +P +  + + EDE  G  V 
Sbjct: 3492 RAQEWYQLQIQASDSGIPPLSSLTSVRVHVTEQSHYAPSALPLEIFITVGEDEFQGGMVG 3551

Query: 387  TLTATDADEDNRLHYEITGGNTRGR-FSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445
             + ATD D  + L Y +    T GR FS+ + +G+  I  AQ L       Y   V+ +D
Sbjct: 3552 KIHATDRDPQDTLTYSLAEEETLGRHFSVGAPDGK--IIAAQGL---PRGHYSFNVTVSD 3606

Query: 446  SGGRSDTAMVQINI 459
             G  + TA V + +
Sbjct: 3607 -GTFTTTAGVHVYV 3619



 Score =  150 bits (363), Expect = 6e-34
 Identities = 129/418 (30%), Positives = 197/418 (47%), Gaps = 32/418 (7%)

Query: 450  SDTAMVQINITDANNYAPVFENA-PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508
            SD     ++    N+Y P FE+  P +  V E  PI T +  ++ATD D G N ++ Y +
Sbjct: 695  SDEEFTSLSTYQINHYTPQFEDHFPQSIDVLESVPINTPLARLAATDPDAGFNGKLVYVI 754

Query: 509  SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568
            +    NE     +  F I  +TG +T    LD E  + Y+L VT  D G P  S    + 
Sbjct: 755  AD--GNE-----EGCFDIELETGLLTVAAPLDYEATNFYILNVTVYDLGTPQKSSWKLLT 807

Query: 569  ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE-LDPKDREE 627
            ++V D NDN P F    Y   I ED  VGT+++++   DAD   NGR+ Y  L P ++  
Sbjct: 808  VNVKDWNDNAPRFPPGGYQLTISEDTEVGTTIAELTTKDADSEDNGRVRYTLLSPTEK-- 865

Query: 628  GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS--STVIVHIKIEDINDSPP 685
              F + P +G +     LDRES   + LK  A D  +      S   + I +ED+ND+ P
Sbjct: 866  --FSLHPLTGELVVTGHLDRESEPRYILKVEARDQPSKGHQLFSVTDLIITLEDVNDNSP 923

Query: 686  VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745
               ++     + E+ P GT +  + A DPD GP   V Y +  G    +F ++   G+  
Sbjct: 924  QCITEHNRLKVPEDLPPGTVLTFLDASDPDLGPAGEVRYVLMDG-AHGTFRVDLMTGA-- 980

Query: 746  AELVTMVDLDYESPRKKYELVIRAA--SPPLWNDV--RVEILVTDVNDN--APVMKDFQI 799
              L+   +LD+E  R  Y L + A+    PL       VE++V DVN+N   P    F +
Sbjct: 981  --LILERELDFER-RAGYNLSLWASDGGRPLARRTLCHVEVIVLDVNENLHPPHFASF-V 1036

Query: 800  IFNNYKDCFPVGPFGRVPAY---DADVTDKLQYRILSGNNANLILLNETTGSM-TLSP 853
                 ++  P G    V A    D+ +  +LQY + +G       +N+ TG + TL+P
Sbjct: 1037 HQGQVQENSPSGTQVIVVAAQDDDSGLDGELQYFLRAGTGLAAFSINQDTGMIQTLAP 1094



 Score =  148 bits (359), Expect = 2e-33
 Identities = 165/630 (26%), Positives = 270/630 (42%), Gaps = 45/630 (7%)

Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE-DISVTDNPVIAKIKATDADVGA 183
           P+   LSS+A    +   +   Y   S KTY  S ++  I + +     + +    DV  
Sbjct: 21  PLEGILSSSAWHFTHSHYNATIYENSSPKTYVESFEKMGIYLAEPQWAVRYRIISGDVAN 80

Query: 184 NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
                  ++G    ++  I + S + +L   L+ E   SY L+I+A +      +  T++
Sbjct: 81  VFKTEEYVVGNFCFLR--IRTKSSNTAL---LNREVRDSYTLIIQATEKTLELEA-LTRV 134

Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
           +++I D ND  P F    ++ ++SE++P+   I +V A DAD G NAE  Y    +    
Sbjct: 135 VVHILDQNDLKPLFSPPSYRVTISEDMPLKSPICKVTATDADLGQNAEFYYAFNTRSEM- 193

Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
                  I P SG V  +G+L+   + K++L V A D                       
Sbjct: 194 -----FAIHPTSGVVTVAGKLNVTWRGKHELQVLAVDRMRKISEGNGFGSLAALVVHVEP 248

Query: 364 XXFMPGQYE--VELAEDEPPGTPVVT-LTATDADEDNRLHYEITGGNTRGRF----SITS 416
               P      V    D   GT   T L   ++        E+ GG+    F    S   
Sbjct: 249 ALRKPPAIASVVVTPPDSNDGTTYATVLVDANSSGAEVESVEVVGGDPGKHFKAIKSYAR 308

Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ-INITDANNYAPVFENAPYT 475
            N   L++V      +    + L++ A    G    + ++  ++  +   +  FE A Y 
Sbjct: 309 SNEFSLVSVKDINWMEYLHGFNLSLQARSGSGPYFYSQIRGFHLPPSKLSSLKFEKAVYR 368

Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
             + E +P G+ V++V  T +    N Q     SSE         +  F +N +TG ITT
Sbjct: 369 VQLSEFSPPGSRVVMVRVTPAFP--NLQYVLKPSSE---------NVGFKLNARTGLITT 417

Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
            KL+D    + Y L +    G       +T V I +VD N++ P+F +  Y   + E+  
Sbjct: 418 TKLMDFHDRAHYQLHIRTSPG-----QASTVVVIDIVDCNNHAPLFNRSSYDGTLDENIP 472

Query: 596 VGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFVIDPASGVIRTNKALDRESV-ATH 653
            GTSV  V ATD D G NG + Y +  PK      F IDP  G+I T+K +D E +   +
Sbjct: 473 PGTSVLAVTATDRDHGENGYVTYSIAGPKAL---PFSIDPYLGIISTSKPMDYELMKRIY 529

Query: 654 DLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
             +  A D G+P  +   V + +++ ++ND+ P+FE    T  I ++ P+G +I  + A 
Sbjct: 530 TFRVRASDWGSPFRREKEVSIFLQLRNLNDNQPMFEEVNCTGSIRQDWPVGKSIMTMSAI 589

Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
           D DE  N  + Y I  G++   F L    G
Sbjct: 590 DVDELQN--LKYEIVSGNELEYFDLNHFSG 617



 Score =  128 bits (309), Expect = 2e-27
 Identities = 141/567 (24%), Positives = 238/567 (41%), Gaps = 42/567 (7%)

Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383
           L+RE +  Y L++ AT+      + T                F P  Y V ++ED P  +
Sbjct: 107 LNREVRDSYTLIIQATEKTLELEALTRVVVHILDQNDLKPL-FSPPSYRVTISEDMPLKS 165

Query: 384 PVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443
           P+  +TATDAD      +          F+I   +G  ++TVA  L+     ++ L V A
Sbjct: 166 PICKVTATDADLGQNAEFYYAFNTRSEMFAIHPTSG--VVTVAGKLNVTWRGKHELQVLA 223

Query: 444 TD-------SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496
            D         G    A + +++  A    P   +   T     D+  GTT   V    +
Sbjct: 224 VDRMRKISEGNGFGSLAALVVHVEPALRKPPAIASVVVTPP---DSNDGTTYATVLVDAN 280

Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556
             G   +    +  +      A   + +  + +   ++   +   E + G+ L++ AR G
Sbjct: 281 SSGAEVESVEVVGGDPGKHFKAI--KSYARSNEFSLVSVKDINWMEYLHGFNLSLQARSG 338

Query: 557 GVPSL-SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615
             P   S      +    ++  +  F++ +Y   + E +  G+ V  V  T A   L   
Sbjct: 339 SGPYFYSQIRGFHLPPSKLSSLK--FEKAVYRVQLSEFSPPGSRVVMVRVTPAFPNLQ-- 394

Query: 616 IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675
             Y L P     G F ++  +G+I T K +D    A + L        +P Q+STV+V I
Sbjct: 395 --YVLKPSSENVG-FKLNARTGLITTTKLMDFHDRAHYQLHIRT----SPGQASTVVV-I 446

Query: 676 KIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735
            I D N+  P+F        + EN P GT++  + A D D G N  V YSI  G  +  F
Sbjct: 447 DIVDCNNHAPLFNRSSYDGTLDENIPPGTSVLAVTATDRDHGENGYVTYSI-AGPKALPF 505

Query: 736 SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA--SPPLWNDVRVEIL--VTDVNDNA 791
           S++   G     + T   +DYE  ++ Y   +RA+    P   +  V I   + ++NDN 
Sbjct: 506 SIDPYLGI----ISTSKPMDYELMKRIYTFRVRASDWGSPFRREKEVSIFLQLRNLNDNQ 561

Query: 792 PVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMT 850
           P+ ++     +  +D +PVG     + A D D    L+Y I+SGN      LN  +G ++
Sbjct: 562 PMFEEVNCTGSIRQD-WPVGKSIMTMSAIDVDELQNLKYEIVSGNELEYFDLNHFSGVIS 620

Query: 851 LS-PQLNTNV--PKLATMEVSVTDGVN 874
           L  P +N     P   +++++ +DG N
Sbjct: 621 LKRPFINLTAGQPTSYSLKITASDGKN 647



 Score =  128 bits (309), Expect = 2e-27
 Identities = 102/326 (31%), Positives = 164/326 (50%), Gaps = 24/326 (7%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV 425
           F    Y V+L+E  PPG+ VV +  T A  +  L Y +   +    F + ++ G  LIT 
Sbjct: 362 FEKAVYRVQLSEFSPPGSRVVMVRVTPAFPN--LQYVLKPSSENVGFKLNARTG--LITT 417

Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
            + +DF     Y L +    S G++ T +V I+I D NN+AP+F  + Y  ++ E+ P G
Sbjct: 418 TKLMDFHDRAHYQLHIRT--SPGQASTVVV-IDIVDCNNHAPLFNRSSYDGTLDENIPPG 474

Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
           T+VL V+ATD D G N  +TYS++     +A+      F I+P  G I+T+K +D E M 
Sbjct: 475 TSVLAVTATDRDHGENGYVTYSIAGP---KAL-----PFSIDPYLGIISTSKPMDYELMK 526

Query: 546 G-YLLTVTARDGGVPSLSD-TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
             Y   V A D G P   +    + + + ++NDN+P+F++   T +I +D  VG S+  +
Sbjct: 527 RIYTFRVRASDWGSPFRREKEVSIFLQLRNLNDNQPMFEEVNCTGSIRQDWPVGKSIMTM 586

Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA---LDRESVATHDLKAVAI 660
            A D D   N  + YE+     E   F ++  SGVI   +    L      ++ LK  A 
Sbjct: 587 SAIDVDELQN--LKYEI-VSGNELEYFDLNHFSGVISLKRPFINLTAGQPTSYSLKITAS 643

Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPV 686
           DG      +T+ + + ++D +   PV
Sbjct: 644 DGKNYASPTTLNITV-VKDPHFEVPV 668



 Score =  107 bits (256), Expect = 6e-21
 Identities = 80/279 (28%), Positives = 136/279 (48%), Gaps = 19/279 (6%)

Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           ++Y +   +  + F +++ +G ++  K +D+     Y+L IR     SP +++T  ++I+
Sbjct: 393 LQYVLKPSSENVGFKLNARTGLITTTKLMDFHDRAHYQLHIRT----SPGQASTV-VVID 447

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
           I D N++AP F  S +  ++ EN+P G S++ V A D D G N  +TY++      G   
Sbjct: 448 IVDCNNHAPLFNRSSYDGTLDENIPPGTSVLAVTATDRDHGENGYVTYSI-----AGPKA 502

Query: 307 LPITIDPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDP-PRSATATXXXXXXXXXXXXX 364
           LP +IDP  G + TS  +D E   + Y   V A+D G P  R    +             
Sbjct: 503 LPFSIDPYLGIISTSKPMDYELMKRIYTFRVRASDWGSPFRREKEVSIFLQLRNLNDNQP 562

Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLIT 424
            F        + +D P G  ++T++A D DE   L YEI  GN    F +   +  G+I+
Sbjct: 563 MFEEVNCTGSIRQDWPVGKSIMTMSAIDVDELQNLKYEIVSGNELEYFDL--NHFSGVIS 620

Query: 425 VAQP---LDFKQERRYVLTVSATDSGGRSDTAMVQINIT 460
           + +P   L   Q   Y L ++A+D  G++  +   +NIT
Sbjct: 621 LKRPFINLTAGQPTSYSLKITASD--GKNYASPTTLNIT 657



 Score =  105 bits (253), Expect = 1e-20
 Identities = 139/579 (24%), Positives = 247/579 (42%), Gaps = 72/579 (12%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           +++LD ND  P+F    Y  ++ E     + +  + ATD D+G+NAE  Y          
Sbjct: 136 VHILDQNDLKPLFSPPSYRVTISEDMPLKSPICKVTATDADLGQNAEFYYAFN------- 188

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD-- 128
                            ++F I   SG +     L+     ++ + V A D+   +S+  
Sbjct: 189 --------------TRSEMFAIHPTSGVVTVAGKLNVTWRGKHELQVLAVDRMRKISEGN 234

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
              S A + V++       P  +    T   D +   T   V+    ++ A+V +     
Sbjct: 235 GFGSLAALVVHVEPALRKPPAIASVVVT-PPDSNDGTTYATVLVDANSSGAEVES----- 288

Query: 189 YAIIGGNTQMQF-SIDSL--SGDVSLVKTLD---YEQVRSYRLVIRAQDGGSPSRSNTTQ 242
             ++GG+    F +I S   S + SLV   D    E +  + L ++A+ G  P   +  +
Sbjct: 289 VEVVGGDPGKHFKAIKSYARSNEFSLVSVKDINWMEYLHGFNLSLQARSGSGPYFYSQIR 348

Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
              ++     ++ +F  ++++  +SE  P G  +V V+   A       L Y +  K  +
Sbjct: 349 -GFHLPPSKLSSLKFEKAVYRVQLSEFSPPGSRVVMVRVTPA----FPNLQYVL--KPSS 401

Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
            NV     ++ R+G + T+  +D   +A YQL +  +     P  A+             
Sbjct: 402 ENVG--FKLNARTGLITTTKLMDFHDRAHYQLHIRTS-----PGQASTVVVIDIVDCNNH 454

Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGR 420
              F    Y+  L E+ PPGT V+ +TATD D  E+  + Y I G      FSI      
Sbjct: 455 APLFNRSSYDGTLDENIPPGTSVLAVTATDRDHGENGYVTYSIAGPKAL-PFSIDPY--L 511

Query: 421 GLITVAQPLDFK-QERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTA 476
           G+I+ ++P+D++  +R Y   V A+D G    R     + + + + N+  P+FE    T 
Sbjct: 512 GIISTSKPMDYELMKRIYTFRVRASDWGSPFRREKEVSIFLQLRNLNDNQPMFEEVNCTG 571

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
           S+ +D P+G +++ +SA D D   N  + Y + S   NE      + F +N  +G I+  
Sbjct: 572 SIRQDWPVGKSIMTMSAIDVDELQN--LKYEIVS--GNEL-----EYFDLNHFSGVISLK 622

Query: 537 KLLDRETM---SGYLLTVTARDGGVPSLSDTTDVEISVV 572
           +     T    + Y L +TA DG   + +  T + I+VV
Sbjct: 623 RPFINLTAGQPTSYSLKITASDG--KNYASPTTLNITVV 659



 Score = 93.9 bits (223), Expect = 6e-17
 Identities = 76/249 (30%), Positives = 118/249 (47%), Gaps = 31/249 (12%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I+++DCN+H+P+F    Y+ ++ E    GT+VL + ATD+D G+N  V Y+I        
Sbjct: 446 IDIVDCNNHAPLFNRSSYDGTLDENIPPGTSVLAVTATDRDHGENGYVTYSI-------A 498

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSDR 129
            P+                F ID   G + T   +D E + R YT  V+A+D  SP   R
Sbjct: 499 GPKAL-------------PFSIDPYLGIISTSKPMDYELMKRIYTFRVRASDWGSPF--R 543

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
                +I + + + NDN P F E   T S+ +D  V  +  I  + A D D   N  ++Y
Sbjct: 544 REKEVSIFLQLRNLNDNQPMFEEVNCTGSIRQDWPVGKS--IMTMSAIDVDELQN--LKY 599

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVK---TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            I+ GN    F ++  SG +SL +    L   Q  SY L I A DG + +   T  + + 
Sbjct: 600 EIVSGNELEYFDLNHFSGVISLKRPFINLTAGQPTSYSLKITASDGKNYASPTTLNITV- 658

Query: 247 IRDVNDNAP 255
           ++D +   P
Sbjct: 659 VKDPHFEVP 667



 Score = 62.1 bits (144), Expect = 2e-07
 Identities = 44/130 (33%), Positives = 72/130 (55%), Gaps = 10/130 (7%)

Query: 103 ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162
           A L+RE    YT++++AT++       L +   + V+I+D ND  P FS  +Y V++ ED
Sbjct: 105 ALLNREVRDSYTLIIQATEKTL----ELEALTRVVVHILDQNDLKPLFSPPSYRVTISED 160

Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ-FSIDSLSGDVSLVKTLDYEQVR 221
           + +  +P I K+ ATDAD+G N+   YA    NT+ + F+I   SG V++   L+     
Sbjct: 161 MPL-KSP-ICKVTATDADLGQNAEFYYAF---NTRSEMFAIHPTSGVVTVAGKLNVTWRG 215

Query: 222 SYRLVIRAQD 231
            + L + A D
Sbjct: 216 KHELQVLAVD 225



 Score = 44.4 bits (100), Expect = 0.046
 Identities = 66/255 (25%), Positives = 102/255 (40%), Gaps = 51/255 (20%)

Query: 1103 CELRARSFPVSSFLTF--PGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELV 1160
            C   A  F   S++ +  P  +  H IH  LK  T     +LL+    NE    ++L+L 
Sbjct: 3771 CNGTATRFSGQSYVRYRAPAARNWH-IHFYLK--TLQPQAILLFT---NETAS-VSLKLA 3823

Query: 1161 SSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKVLS 1220
            S      G P L +   LGG    ++ + +V D  WH++ +E  + +I +++D       
Sbjct: 3824 S------GVPQLEYH-CLGGFYGNLSSQRHVNDHEWHSILVEEMDASIRLMVDSMGN--- 3873

Query: 1221 LAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNKD 1280
                            T  V+P  C        R L     L +GGL  + SS  V ++ 
Sbjct: 3874 ----------------TSLVVPENC--------RGLRPERHLLLGGLILLHSSSNV-SQG 3908

Query: 1281 FVGCISDFYIDHKFIDL---NSYVA---DNGTLAGCPEKRSRCSSAPCYNGAECSDLWDT 1334
            F GC+    ++ + +DL      VA   +   L  C      CS   C NG +CS     
Sbjct: 3909 FEGCLDAVVVNEEALDLLAPGKTVAGLLETQALTQCCLHSDYCSQNTCLNGGKCSWTHGA 3968

Query: 1335 -YICDCKEGHTGKDC 1348
             Y+C C    +GK C
Sbjct: 3969 GYVCKCPPQFSGKHC 3983



 Score = 38.7 bits (86), Expect = 2.3
 Identities = 61/263 (23%), Positives = 98/263 (37%), Gaps = 34/263 (12%)

Query: 1343 HTGKDCADSTGPPWRFGGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVM--------S 1394
            H  + C+   G   RF G   + +     P    W     ++T Q  A ++        S
Sbjct: 3764 HLQRSCS-CNGTATRFSGQSYVRYRA---PAARNWHIHFYLKTLQPQAILLFTNETASVS 3819

Query: 1395 IQLKSGLLHYSYNG-ETMYLPMAT---LSDGAWHRIEIKWLGTDISVTVD-YGLRTVLMP 1449
            ++L SG+    Y+     Y  +++   ++D  WH I ++ +   I + VD  G  ++++P
Sbjct: 3820 LKLASGVPQLEYHCLGGFYGNLSSQRHVNDHEWHSILVEEMDASIRLMVDSMGNTSLVVP 3879

Query: 1450 MLANKIQGQYIGKILIGGLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRP------TV 1503
                 ++ +    +L+GGL           GF EGC+  V +      L  P       +
Sbjct: 3880 ENCRGLRPER--HLLLGGLILLHSSSNVSQGF-EGCLDAVVVNEEALDLLAPGKTVAGLL 3936

Query: 1504 RENVRDGCQSRAD-CMLSICPPYSKCV-TSWDSSTCTCEAGRVGPQCVSA---CELGPC- 1557
                   C   +D C  + C    KC  T      C C     G  C      C   PC 
Sbjct: 3937 ETQALTQCCLHSDYCSQNTCLNGGKCSWTHGAGYVCKCPPQFSGKHCEQGRENCTFAPCL 3996

Query: 1558 GAARCVPDQTPKGYSCACEPGYT 1580
                C+   +PKG SC C   YT
Sbjct: 3997 EGGTCI--LSPKGASCNCPHPYT 4017



 Score = 37.5 bits (83), Expect = 5.3
 Identities = 38/166 (22%), Positives = 65/166 (39%), Gaps = 7/166 (4%)

Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAEL-----VTMVDLDYESPRKKYELVIRAASP 772
           P   V Y I  GD +N F  E     +   L      +   L     R  Y L+I+A   
Sbjct: 65  PQWAVRYRIISGDVANVFKTEEYVVGNFCFLRIRTKSSNTALLNREVRDSYTLIIQATEK 124

Query: 773 PLWNDV--RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYR 830
            L  +   RV + + D ND  P+           +D     P  +V A DAD+    ++ 
Sbjct: 125 TLELEALTRVVVHILDQNDLKPLFSPPSYRVTISEDMPLKSPICKVTATDADLGQNAEFY 184

Query: 831 ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEI 876
                 + +  ++ T+G +T++ +LN        ++V   D + +I
Sbjct: 185 YAFNTRSEMFAIHPTSGVVTVAGKLNVTWRGKHELQVLAVDRMRKI 230


>UniRef50_UPI0000F1D37C Cluster: PREDICTED: hypothetical protein; n=3;
            Danio rerio|Rep: PREDICTED: hypothetical protein - Danio
            rerio
          Length = 3267

 Score =  336 bits (827), Expect = 4e-90
 Identities = 265/859 (30%), Positives = 424/859 (49%), Gaps = 75/859 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + VLD NDH PVF+   Y  +V E    G  ++ +   D D   N+ V Y+        L
Sbjct: 1611 VKVLDVNDHPPVFQQHIYNTTVIENRDPGEIIVQVTTVDLDSEVNSAVSYS--------L 1662

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             P               ++FRI+  +G + T   LDRE  + +T+ V+A D  +P    L
Sbjct: 1663 LPGPGY-----------ELFRINSHTGHISTSVRLDREIQSTFTLRVQAEDSGTP---SL 1708

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            SST T+  +++D+NDN PQFS+    + + E+++     VI  ++A+D D G N  I+Y+
Sbjct: 1709 SSTTTVLCSVLDENDNAPQFSQPDLHIVIPENLA---PGVIHIVQASDIDNGLNGTIQYS 1765

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I        FSID+++G +   + LD E+  +Y L+I A D G P  S++  L I + D 
Sbjct: 1766 I---EDLECFSIDAVTGMIRTTRPLDREERSNYSLLITAADHGHPPLSSSALLHITLTDE 1822

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN+P F    ++ S+SE +P+G  I+ + A+D DEG N  +T+++ +++ +GN      
Sbjct: 1823 NDNSPLFARKSYRASISEGLPVGTEILHLIAWDPDEGANGVVTFSL-EEENSGN----FH 1877

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDG-GDPPRSATATXXXXXXXXXXXXXXFMPG 369
            +D  +G +  +  LDRET++++     ATDG  + PRS+ AT               +  
Sbjct: 1878 VDGSTGVIKLTKPLDRETRSQHVFRAVATDGCSEGPRSSIATVTIQVEDINDNTPACVKE 1937

Query: 370  QYEVELAE-DEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
               V ++  +  P  P+  +TA D D  +              F +   +G G + +  P
Sbjct: 1938 PMRVSVSSVNTRPNRPIAKVTAQDPDLGDNGTVVFRLPEEDELFQV---DGSGAVRLKAP 1994

Query: 429  LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV--FENAPYTASVFEDAPIGT 486
            L  +     +L + A D G  S T+   + +   N+  P+  F    Y  +V E++  G+
Sbjct: 1995 LSNEVSGTKLLRIRAEDLGRPSLTSSCLL-LIQLNDEEPLLQFTEELYEVAVPENSKTGS 2053

Query: 487  TVLVVSATD--SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN--KLLDRE 542
             V  V A D  SD G+   I Y++ S   NEA       F+INP TG IT N  +LLD E
Sbjct: 2054 WVANVVAHDQTSDEGM---IKYNIFSGNENEA-------FIINPVTGDITVNDQRLLDFE 2103

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
                  L V A +G   + +    V I++ D+NDN PVFKQ  Y   + E  +  T V Q
Sbjct: 2104 VQRKVQLVVLAENGHQTAYA---RVAITLQDINDNAPVFKQSYYRTAVWEGQIHNTYVMQ 2160

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
            V ATD+D G+NG+I Y +        +FVID   G++ TN  LDRE V+++ L   A D 
Sbjct: 2161 VLATDSDSGVNGQISYFI-MDGNHNNAFVIDSVRGILATNAVLDREIVSSYKLIIQAKDM 2219

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVFES-DCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
            G  P + T  V +++ D+ND+ P   S + +T  I+EN P+G  +  + A+D D  P+A 
Sbjct: 2220 GKAPLTGTCTVRVQVVDVNDNSPTIPSMEAVT--IAENLPLGYIVTRVIANDVDLSPSA- 2276

Query: 722  VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781
             +  I+  D S SF+++   G     + T   LDYE  +  Y L ++A+      +  + 
Sbjct: 2277 TYRLIEKDDTSRSFAIDLYTGI----ITTTKILDYEE-QSVYTLKVQASDSVHQTEAELS 2331

Query: 782  ILVTDVNDNAPV--MKDFQIIFN--NYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNA 837
            I V DVNDN+PV   + +Q++ +     D F V         D+    ++ YR+LS +  
Sbjct: 2332 IQVLDVNDNSPVFSQESYQVLLSERTLADTFVVSVL--ATDKDSGKNGRVSYRLLS-SPV 2388

Query: 838  NLILLNETTGSMTLSPQLN 856
                ++   GS+  +  LN
Sbjct: 2389 GGFYIDPDNGSVFTNKPLN 2407



 Score =  322 bits (790), Expect = 1e-85
 Identities = 266/896 (29%), Positives = 407/896 (45%), Gaps = 76/896 (8%)

Query: 12   NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71
            +VLD ND++P F        + E  + G  +  ++A+D D G N  ++Y+IE +      
Sbjct: 1717 SVLDENDNAPQFSQPDLHIVIPENLAPGV-IHIVQASDIDNGLNGTIQYSIEDL------ 1769

Query: 72   PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131
                            + F ID  +G + T   LDRE+ + Y++L+ A D   P    LS
Sbjct: 1770 ----------------ECFSIDAVTGMIRTTRPLDREERSNYSLLITAADHGHPP---LS 1810

Query: 132  STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191
            S+A +H+ + D+NDN P F+ K+Y  S+ E + V     I  + A D D GAN  + +++
Sbjct: 1811 SSALLHITLTDENDNSPLFARKSYRASISEGLPVGTE--ILHLIAWDPDEGANGVVTFSL 1868

Query: 192  IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLINIRDV 250
               N+   F +D  +G + L K LD E    +     A DG S   RS+   + I + D+
Sbjct: 1869 EEENSG-NFHVDGSTGVIKLTKPLDRETRSQHVFRAVATDGCSEGPRSSIATVTIQVEDI 1927

Query: 251  NDNAPRFYTSLFQESVSE-NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            NDN P       + SVS  N      I +V A D D G N  + + + ++D    VD   
Sbjct: 1928 NDNTPACVKEPMRVSVSSVNTRPNRPIAKVTAQDPDLGDNGTVVFRLPEEDELFQVD--- 1984

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
                 SG V     L  E      L + A D G P  +++                F   
Sbjct: 1985 ----GSGAVRLKAPLSNEVSGTKLLRIRAEDLGRPSLTSSCLLLIQLNDEEPLLQ-FTEE 2039

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDN-RLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
             YEV + E+   G+ V  + A D   D   + Y I  GN    F I    G   +   + 
Sbjct: 2040 LYEVAVPENSKTGSWVANVVAHDQTSDEGMIKYNIFSGNENEAFIINPVTGDITVNDQRL 2099

Query: 429  LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
            LDF+ +R+  L V A ++G ++  A V I + D N+ APVF+ + Y  +V+E     T V
Sbjct: 2100 LDFEVQRKVQLVVLA-ENGHQTAYARVAITLQDINDNAPVFKQSYYRTAVWEGQIHNTYV 2158

Query: 489  LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
            + V ATDSD G+N QI+Y +          +H+  FVI+   G + TN +LDRE +S Y 
Sbjct: 2159 MQVLATDSDSGVNGQISYFIMD-------GNHNNAFVIDSVRGILATNAVLDREIVSSYK 2211

Query: 549  LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
            L + A+D G   L+ T  V + VVDVNDN P     +    I E+  +G  V++V A D 
Sbjct: 2212 LIIQAKDMGKAPLTGTCTVRVQVVDVNDNSPTI-PSMEAVTIAENLPLGYIVTRVIANDV 2270

Query: 609  DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
            D  L+    Y L  KD    SF ID  +G+I T K LD E  + + LK  A D     ++
Sbjct: 2271 D--LSPSATYRLIEKDDTSRSFAIDLYTGIITTTKILDYEEQSVYTLKVQASDSVHQTEA 2328

Query: 669  STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
                + I++ D+ND+ PVF  +     +SE +   T +  + A D D G N  V Y +  
Sbjct: 2329 E---LSIQVLDVNDNSPVFSQESYQVLLSERTLADTFVVSVLATDKDSGKNGRVSYRLL- 2384

Query: 729  GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVT 785
                  F ++   GS    + T   L+Y +      L++ A     P L+    V+I V 
Sbjct: 2385 SSPVGGFYIDPDNGS----VFTNKPLNYVANGNVLRLLVEARDSGDPNLFCVTSVDIEVA 2440

Query: 786  DVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK---LQYRILSGNNANLILL 842
            D NDNAP         N  +D         + A D D +D+   L+Y I+SGN+     L
Sbjct: 2441 DFNDNAPFFTQNSYQINIPEDVSVGSTLITLLAEDKDYSDENTHLEYLIISGNDERRFCL 2500

Query: 843  ----------NETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLI 887
                      + T G + L   L+       ++ V+VTD G+N + +   +SV+++
Sbjct: 2501 EVVSIQAEPHSRTVGQLVLCDTLDRETTDAYSLTVTVTDRGINPLNSSTVVSVKVL 2556



 Score =  316 bits (777), Expect = 4e-84
 Identities = 271/898 (30%), Positives = 416/898 (46%), Gaps = 65/898 (7%)

Query: 11   INVLDCNDHSPVFEMQQY--EASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68
            I V D ND+ P F       E +V       + V+++ A D D G+N  V++++   T +
Sbjct: 1187 ITVTDVNDNRPQFTHMPSTKELNVWAVIPVNSVVISMFAKDLDAGENGTVKFSM---TDN 1243

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
             L                   F ID  SG +   +        RYT+ V ATD       
Sbjct: 1244 QLGH-----------------FSIDSLSGDVKVTSQFSSNPQMRYTLRVVATDNGL---F 1283

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             L  TA +H+ +   +     F       +V ED+ +    +I  +  ++A    ++ +R
Sbjct: 1284 PLEETAVVHIQVYVLDQQKENFQSSFQHFTVLEDVGL--GTIIGSLGVSNAP---DTELR 1338

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            Y+I+ GN  +QF I S SG++ + + LDYE  + Y LV+RA+    P+ + T    ++I 
Sbjct: 1339 YSIVEGNGSLQFGIKSSSGELYVAQHLDYEVTQRYFLVVRAE--AFPTFNVTVFAAVSIL 1396

Query: 249  DVNDNAPRFYTS--LFQESVSENVPIGYSIVRVQAYDADEGVN-AELTYTMTDKDYTGNV 305
            DVND+ P F ++  +    V E+V  G  +    A D D  ++ +EL Y++T        
Sbjct: 1397 DVNDHNPWFPSNGNIVIFGVHEDVSNGTVVYVFNARDGDGSLHYSELYYSLTFDPSPAIE 1456

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP---RSATATXXXXXXXXXXX 362
             LP+ IDP +G V T+GQLDRE        VTA+D    P   ++A+             
Sbjct: 1457 GLPLHIDPHTGVVTTNGQLDRERTENIIFRVTASDSLKEPNERKNASIIAQMIVLDINDN 1516

Query: 363  XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNGR 420
               F+       + ED   G  V  + A D DE    H  Y ++ GN +  F + S    
Sbjct: 1517 SPTFVSMDIAC-VPEDTEVGLLVHHVMAKDKDEGRNGHVTYSVSSGNEKSYFHMEST--- 1572

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASV 478
            G + +   LD++ +  ++L V A D+G    S T  + + + D N++ PVF+   Y  +V
Sbjct: 1573 GHLFLNSSLDYESQHVHILIVQARDNGVPSLSSTQTLTVKVLDVNDHPPVFQQHIYNTTV 1632

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             E+   G  ++ V+  D D  +N+ ++YSL      E        F IN  TG I+T+  
Sbjct: 1633 IENRDPGEIIVQVTTVDLDSEVNSAVSYSLLPGPGYEL-------FRINSHTGHISTSVR 1685

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            LDRE  S + L V A D G PSLS TT V  SV+D NDN P F Q      I E+   G 
Sbjct: 1686 LDREIQSTFTLRVQAEDSGTPSLSSTTTVLCSVLDENDNAPQFSQPDLHIVIPENLAPGV 1745

Query: 599  SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
             +  V A+D D GLNG I Y ++  D E   F ID  +G+IRT + LDRE  + + L   
Sbjct: 1746 -IHIVQASDIDNGLNGTIQYSIE--DLE--CFSIDAVTGMIRTTRPLDREERSNYSLLIT 1800

Query: 659  AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
            A D G PP SS+ ++HI + D ND+ P+F        ISE  P+GT I  + A DPDEG 
Sbjct: 1801 AADHGHPPLSSSALLHITLTDENDNSPLFARKSYRASISEGLPVGTEILHLIAWDPDEGA 1860

Query: 719  NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP-PLWND 777
            N VV +S++  ++S +F ++   G  K  L   +D +  S      +     S  P  + 
Sbjct: 1861 NGVVTFSLE-EENSGNFHVDGSTGVIK--LTKPLDRETRSQHVFRAVATDGCSEGPRSSI 1917

Query: 778  VRVEILVTDVNDNAPV-MKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNN 836
              V I V D+NDN P  +K+   +  +  +  P  P  +V A D D+ D           
Sbjct: 1918 ATVTIQVEDINDNTPACVKEPMRVSVSSVNTRPNRPIAKVTAQDPDLGDNGTVVFRLPEE 1977

Query: 837  ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEEMLL 893
              L  + + +G++ L   L+  V     + +   D G   + +   L ++L  EE LL
Sbjct: 1978 DELFQV-DGSGAVRLKAPLSNEVSGTKLLRIRAEDLGRPSLTSSCLLLIQLNDEEPLL 2034



 Score =  312 bits (766), Expect = 9e-83
 Identities = 258/890 (28%), Positives = 419/890 (47%), Gaps = 77/890 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            Q+ VLD ND+SP F      A V E    G  V  + A D+D G+N  V Y++       
Sbjct: 1507 QMIVLDINDNSPTFVSMDI-ACVPEDTEVGLLVHHVMAKDKDEGRNGHVTYSV------- 1558

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                             +  F ++  +G L   +SLD E    + ++V+A D   P    
Sbjct: 1559 ------------SSGNEKSYFHMES-TGHLFLNSSLDYESQHVHILIVQARDNGVP---S 1602

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            LSST T+ V ++D ND+ P F +  Y  +V E+       +I ++   D D   NSA+ Y
Sbjct: 1603 LSSTQTLTVKVLDVNDHPPVFQQHIYNTTVIENRD--PGEIIVQVTTVDLDSEVNSAVSY 1660

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            +++ G     F I+S +G +S    LD E   ++ L ++A+D G+PS S+TT +L ++ D
Sbjct: 1661 SLLPGPGYELFRINSHTGHISTSVRLDREIQSTFTLRVQAEDSGTPSLSSTTTVLCSVLD 1720

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
             NDNAP+F        + EN+  G  I  VQA D D G+N  + Y++ D +         
Sbjct: 1721 ENDNAPQFSQPDLHIVIPENLAPGV-IHIVQASDIDNGLNGTIQYSIEDLEC-------F 1772

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            +ID  +G + T+  LDRE ++ Y LL+TA D G PP S++A               F   
Sbjct: 1773 SIDAVTGMIRTTRPLDREERSNYSLLITAADHGHPPLSSSALLHITLTDENDNSPLFARK 1832

Query: 370  QYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
             Y   ++E  P GT ++ L A D DE  +  + + +   N+ G F +      G+I + +
Sbjct: 1833 SYRASISEGLPVGTEILHLIAWDPDEGANGVVTFSLEEENS-GNFHV--DGSTGVIKLTK 1889

Query: 428  PLDFKQERRYVLTVSATD---SGGRSDTAMVQINITDANNYAPVFENAPYTASVFE-DAP 483
            PLD +   ++V    ATD    G RS  A V I + D N+  P     P   SV   +  
Sbjct: 1890 PLDRETRSQHVFRAVATDGCSEGPRSSIATVTIQVEDINDNTPACVKEPMRVSVSSVNTR 1949

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
                +  V+A D D+G N  + + L  E         D+ F ++  +GA+     L  E 
Sbjct: 1950 PNRPIAKVTAQDPDLGDNGTVVFRLPEE---------DELFQVD-GSGAVRLKAPLSNEV 1999

Query: 544  MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV--FKQQLYTANIMEDALVGTSVS 601
                LL + A D G PSL+ +    + ++ +ND EP+  F ++LY   + E++  G+ V+
Sbjct: 2000 SGTKLLRIRAEDLGRPSLTSSC---LLLIQLNDEEPLLQFTEELYEVAVPENSKTGSWVA 2056

Query: 602  QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN--KALDRESVATHDLKAVA 659
             V A D      G I Y +   +  E +F+I+P +G I  N  + LD E      L  +A
Sbjct: 2057 NVVAHD-QTSDEGMIKYNIFSGNENE-AFIINPVTGDITVNDQRLLDFEVQRKVQLVVLA 2114

Query: 660  IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
             +G    Q++   V I ++DIND+ PVF+       + E     T + ++ A D D G N
Sbjct: 2115 ENG---HQTAYARVAITLQDINDNAPVFKQSYYRTAVWEGQIHNTYVMQVLATDSDSGVN 2171

Query: 720  AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776
              + Y I  G+ +N+F +++ +G     L T   LD E     Y+L+I+A      PL  
Sbjct: 2172 GQISYFIMDGNHNNAFVIDSVRGI----LATNAVLDREIV-SSYKLIIQAKDMGKAPLTG 2226

Query: 777  DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDKLQYRIL-SG 834
               V + V DVNDN+P +   + +     +  P+G    RV A D D++    YR++   
Sbjct: 2227 TCTVRVQVVDVNDNSPTIPSMEAV--TIAENLPLGYIVTRVIANDVDLSPSATYRLIEKD 2284

Query: 835  NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884
            + +    ++  TG +T +  L+     + T++V  +D V++ +A + + V
Sbjct: 2285 DTSRSFAIDLYTGIITTTKILDYEEQSVYTLKVQASDSVHQTEAELSIQV 2334



 Score =  310 bits (761), Expect = 4e-82
 Identities = 249/863 (28%), Positives = 400/863 (46%), Gaps = 63/863 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEA--SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68
            +++LD NDH+P F          V E  S+GT V    A D D      + Y+ EL  + 
Sbjct: 1393 VSILDVNDHNPWFPSNGNIVIFGVHEDVSNGTVVYVFNARDGD----GSLHYS-ELYYSL 1447

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
            T +P  A                ID  +G + T   LDRE+       V A+D     ++
Sbjct: 1448 TFDPSPAIEGL---------PLHIDPHTGVVTTNGQLDRERTENIIFRVTASDSLKEPNE 1498

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            R +++    + ++D NDN P F        V ED  V    ++  + A D D G N  + 
Sbjct: 1499 RKNASIIAQMIVLDINDNSPTFVSMD-IACVPEDTEV--GLLVHHVMAKDKDEGRNGHVT 1555

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            Y++  GN +  F ++S +G + L  +LDYE    + L+++A+D G PS S+T  L + + 
Sbjct: 1556 YSVSSGNEKSYFHMES-TGHLFLNSSLDYESQHVHILIVQARDNGVPSLSSTQTLTVKVL 1614

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            DVND+ P F   ++  +V EN   G  IV+V   D D  VN+ ++Y++         +L 
Sbjct: 1615 DVNDHPPVFQQHIYNTTVIENRDPGEIIVQVTTVDLDSEVNSAVSYSLLPGP---GYEL- 1670

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
              I+  +G + TS +LDRE Q+ + L V A D G P  S+T T              F  
Sbjct: 1671 FRINSHTGHISTSVRLDREIQSTFTLRVQAEDSGTPSLSSTTTVLCSVLDENDNAPQFSQ 1730

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
                + + E+  PG  +  + A+D D   +  + Y I        FSI +    G+I   
Sbjct: 1731 PDLHIVIPENLAPGV-IHIVQASDIDNGLNGTIQYSIEDLEC---FSIDAVT--GMIRTT 1784

Query: 427  QPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
            +PLD ++   Y L ++A D G    S +A++ I +TD N+ +P+F    Y AS+ E  P+
Sbjct: 1785 RPLDREERSNYSLLITAADHGHPPLSSSALLHITLTDENDNSPLFARKSYRASISEGLPV 1844

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            GT +L + A D D G N  +T+SL  E S          F ++  TG I   K LDRET 
Sbjct: 1845 GTEILHLIAWDPDEGANGVVTFSLEEENSG--------NFHVDGSTGVIKLTKPLDRETR 1896

Query: 545  SGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEPV-FKQQLYTANIMEDALVGTSVSQ 602
            S ++    A DG      S    V I V D+NDN P   K+ +  +    +      +++
Sbjct: 1897 SQHVFRAVATDGCSEGPRSSIATVTIQVEDINDNTPACVKEPMRVSVSSVNTRPNRPIAK 1956

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
            V A D D+G NG + + L  +D     F +D  SG +R    L  E   T  L+  A D 
Sbjct: 1957 VTAQDPDLGDNGTVVFRLPEEDE---LFQVD-GSGAVRLKAPLSNEVSGTKLLRIRAEDL 2012

Query: 663  GTPPQSSTVIVHIKIEDINDSPPV--FESDCLTFYISENSPIGTTIGEIRAHD--PDEGP 718
            G P  +S+ ++ I+   +ND  P+  F  +     + ENS  G+ +  + AHD   DEG 
Sbjct: 2013 GRPSLTSSCLLLIQ---LNDEEPLLQFTEELYEVAVPENSKTGSWVANVVAHDQTSDEG- 2068

Query: 719  NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDV 778
              ++ Y+I  G+++ +F +    G        ++D + +   +K +LV+ A +       
Sbjct: 2069 --MIKYNIFSGNENEAFIINPVTGDITVNDQRLLDFEVQ---RKVQLVVLAENGHQTAYA 2123

Query: 779  RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNN 836
            RV I + D+NDNAPV K        ++         +V A D+D  V  ++ Y I+ GN+
Sbjct: 2124 RVAITLQDINDNAPVFKQSYYRTAVWEGQIHNTYVMQVLATDSDSGVNGQISYFIMDGNH 2183

Query: 837  ANLILLNETTGSMTLSPQLNTNV 859
             N  +++   G +  +  L+  +
Sbjct: 2184 NNAFVIDSVRGILATNAVLDREI 2206



 Score =  301 bits (739), Expect = 2e-79
 Identities = 234/789 (29%), Positives = 367/789 (46%), Gaps = 47/789 (5%)

Query: 105  LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS 164
            LDRE    Y + V A+D   P    LSS  T  + + D NDN P F +  Y  S+DED+ 
Sbjct: 410  LDREIKDLYELTVTASDYGCPP---LSSVITFQIQVTDVNDNPPVFHQTIYEESIDEDVR 466

Query: 165  VTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR 224
            V     + ++KATD D+G +S I Y+I+    +  F+ID   G ++    LD+E+ R  R
Sbjct: 467  V--GTAVFRVKATDKDLGGDSEIIYSIVQSEQKCPFNIDPTLGVITTAAALDHERERELR 524

Query: 225  LVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA 284
             ++ A DGGSPS S+T  ++I++ DVNDN P F    +  +V E+  +G  I++V A DA
Sbjct: 525  FLVVASDGGSPSLSSTATVIIHVEDVNDNKPIFPQKFYNATVKEHTAVGTCILQVTAIDA 584

Query: 285  DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA-KYQLLVTATDGGD 343
            D      + Y + D     +V     I+  +G +  S  +D E     + LL+ A D   
Sbjct: 585  DGAEFGSVQYFLYDGFSGKDVHPFFHINSVTGNICVSQDIDYEAGLLTFDLLIKAEDQVS 644

Query: 344  -----PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN- 397
                    S+                 F PG+Y   ++    PGT ++ + A+D D  N 
Sbjct: 645  LSFVKDGFSSQTFVHIGIEDVNDNAPVFNPGKYVTSVSVHAQPGTELLNVYASDQDAGNY 704

Query: 398  -RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT--AM 454
             ++ YE+  G++   F  T     G + ++  L   +     L+VSA D GG S    A 
Sbjct: 705  GKITYELQPGDSATLF--TMDQSTGSVYLSSSLMQLRSSSVKLSVSARDGGGMSAAYPAN 762

Query: 455  VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
            + +NI  ++    +F+ A YT S+ EDAP+G++V +V A          IT + S E+ +
Sbjct: 763  ITVNILQSDQPPALFQKAQYTFSISEDAPVGSSVGLVQA----------ITPANSVEVVS 812

Query: 515  EAVAHHDQQ--FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572
              ++  D Q  F I+ QTG I T + LD E++S  +L +    G +P +  +  V +S+ 
Sbjct: 813  YVISSGDPQGFFSIDSQTGIINTAQPLDHESISYVILNIQFHTGTLP-IHSSAQVNVSIT 871

Query: 573  DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632
            D+NDN PVF++      I      GT +    A D D G NGRIHY L PK      F I
Sbjct: 872  DINDNPPVFQKTSEHITISRTTPPGTPLFIAHAHDTDSGFNGRIHYMLHPKSH---LFTI 928

Query: 633  DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN--DSPPVFESD 690
             P  G +  N  + R+S + ++L  +A D G P  SST+ + I+++     D    FE+ 
Sbjct: 929  HPNLGTLMLNGDVSRDSSSRYELSIIAEDEGHPSLSSTLGLVIEMDSSASVDDTLAFETL 988

Query: 691  CLTFYISENSPIGTTIGEIRAH---DPDEGPN----AVVHYSIKGGDDSNSFSLETRQGS 743
                 I E++P  T + ++RAH       G +    +V+ YS+K       F +    G 
Sbjct: 989  VYQVEIGESAPKDTRMIQVRAHGNRSQHTGTSGKETSVITYSLKPLSGVPPFRIHPETGW 1048

Query: 744  DKAELVTMVDLDYES-PRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN 802
                +     LDYE+ P  ++ +  +A +  +     V ++V D NDNAPV       F+
Sbjct: 1049 ----MFVSQSLDYETEPSYRFCVCAKAQNSKMEATATVVVMVQDENDNAPVFSRDVYFFS 1104

Query: 803  NYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKL 862
              +   P G  G V A D D  +      +   +     +N  TG +     L+      
Sbjct: 1105 VQEGPSPHGLIGTVKASDRDSLNNGVLSFILLTDGKYFSVNSRTGEIINLVALDREEQAQ 1164

Query: 863  ATMEVSVTD 871
              + V VTD
Sbjct: 1165 HVLRVMVTD 1173



 Score =  294 bits (722), Expect = 2e-77
 Identities = 237/782 (30%), Positives = 361/782 (46%), Gaps = 64/782 (8%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           +  QI VLD ND+ PVF   +Y A + E A+  T V  + ATD D+G N +V Y I    
Sbjct: 219 LQAQITVLDENDNQPVFNQSEYHAVILENATLMTPVCQIFATDADLGSNGQVIYGINRRQ 278

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
           +D                   + F I   SG +     LD E  + Y ++V A D     
Sbjct: 279 SDP-----------------NEFFIIGSSSGIISVNKHLDYENESYYELIVTAWDSGIQP 321

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFS----EKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
               SS   + + +++ NDN P  S     +     V E     D   +A+I  +D D+G
Sbjct: 322 E---SSNTFVSIKVLNVNDNPPNISVLFLNEAGAPEVSEGAGFED--YVARIAVSDPDLG 376

Query: 183 ANSAIRYAIIGGNTQMQF-SIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
               I   + GG+      S+D     + +   LD E    Y L + A D G P  S+  
Sbjct: 377 DVKKIDVLLQGGDGMFSLRSMDDFLYVLCVDGPLDREIKDLYELTVTASDYGCPPLSSVI 436

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
              I + DVNDN P F+ ++++ES+ E+V +G ++ RV+A D D G ++E+ Y++   + 
Sbjct: 437 TFQIQVTDVNDNPPVFHQTIYEESIDEDVRVGTAVFRVKATDKDLGGDSEIIYSIVQSEQ 496

Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
                 P  IDP  G + T+  LD E + + + LV A+DGG P  S+TAT          
Sbjct: 497 K----CPFNIDPTLGVITTAAALDHERERELRFLVVASDGGSPSLSSTATVIIHVEDVND 552

Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEI----TGGNTRGRFSIT 415
               F    Y   + E    GT ++ +TA DAD  E   + Y +    +G +    F I 
Sbjct: 553 NKPIFPQKFYNATVKEHTAVGTCILQVTAIDADGAEFGSVQYFLYDGFSGKDVHPFFHIN 612

Query: 416 SQNGRGLITVAQPLDFKQER-RYVLTVSATDS-------GGRSDTAMVQINITDANNYAP 467
           S  G   I V+Q +D++     + L + A D         G S    V I I D N+ AP
Sbjct: 613 SVTGN--ICVSQDIDYEAGLLTFDLLIKAEDQVSLSFVKDGFSSQTFVHIGIEDVNDNAP 670

Query: 468 VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527
           VF    Y  SV   A  GT +L V A+D D G   +ITY L    S          F ++
Sbjct: 671 VFNPGKYVTSVSVHAQPGTELLNVYASDQDAGNYGKITYELQPGDSATL-------FTMD 723

Query: 528 PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT 587
             TG++  +  L +   S   L+V+ARDGG  S +   ++ ++++  +    +F++  YT
Sbjct: 724 QSTGSVYLSSSLMQLRSSSVKLSVSARDGGGMSAAYPANITVNILQSDQPPALFQKAQYT 783

Query: 588 ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647
            +I EDA VG+SV  V A      +   + Y +   D  +G F ID  +G+I T + LD 
Sbjct: 784 FSISEDAPVGSSVGLVQAITPANSVEV-VSYVISSGD-PQGFFSIDSQTGIINTAQPLDH 841

Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
           ES++ + +  +    GT P  S+  V++ I DIND+PPVF+       IS  +P GT + 
Sbjct: 842 ESIS-YVILNIQFHTGTLPIHSSAQVNVSITDINDNPPVFQKTSEHITISRTTPPGTPLF 900

Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
              AHD D G N  +HY +     S+ F++    G+    L+   D+  +S   +YEL I
Sbjct: 901 IAHAHDTDSGFNGRIHYMLH--PKSHLFTIHPNLGT----LMLNGDVSRDS-SSRYELSI 953

Query: 768 RA 769
            A
Sbjct: 954 IA 955



 Score =  273 bits (669), Expect = 5e-71
 Identities = 226/799 (28%), Positives = 358/799 (44%), Gaps = 72/799 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I + D ND++PVF   +Y  SV   A  GT +L + A+DQD G   ++ Y ++       
Sbjct: 660  IGIEDVNDNAPVFNPGKYVTSVSVHAQPGTELLNVYASDQDAGNYGKITYELQ------- 712

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             P D+             +F +D  +G++   +SL + + +   + V A D     +   
Sbjct: 713  -PGDSAT-----------LFTMDQSTGSVYLSSSLMQLRSSSVKLSVSARDGGGMSA--- 757

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA--IR 188
            +  A I VNI+  +     F +  YT S+ ED      PV + +    A   ANS   + 
Sbjct: 758  AYPANITVNILQSDQPPALFQKAQYTFSISEDA-----PVGSSVGLVQAITPANSVEVVS 812

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            Y I  G+ Q  FSIDS +G ++  + LD+E +    L I+   G  P  S+  Q+ ++I 
Sbjct: 813  YVISSGDPQGFFSIDSQTGIINTAQPLDHESISYVILNIQFHTGTLPIHSSA-QVNVSIT 871

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            D+NDN P F  +    ++S   P G  +    A+D D G N  + Y +  K +       
Sbjct: 872  DINDNPPVFQKTSEHITISRTTPPGTPLFIAHAHDTDSGFNGRIHYMLHPKSHL------ 925

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA--TXXXXXXXXXXXXXXF 366
             TI P  G +  +G + R++ ++Y+L + A D G P  S+T                  F
Sbjct: 926  FTIHPNLGTLMLNGDVSRDSSSRYELSIIAEDEGHPSLSSTLGLVIEMDSSASVDDTLAF 985

Query: 367  MPGQYEVELAEDEPPGTPVVTL---------TATDADEDNRLHYEITGGNTRGRFSITSQ 417
                Y+VE+ E  P  T ++ +         T T   E + + Y +   +    F I  +
Sbjct: 986  ETLVYQVEIGESAPKDTRMIQVRAHGNRSQHTGTSGKETSVITYSLKPLSGVPPFRIHPE 1045

Query: 418  NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSD-TAMVQINITDANNYAPVFENAPYTA 476
             G   + V+Q LD++ E  Y   V A     + + TA V + + D N+ APVF    Y  
Sbjct: 1046 TG--WMFVSQSLDYETEPSYRFCVCAKAQNSKMEATATVVVMVQDENDNAPVFSRDVYFF 1103

Query: 477  SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
            SV E       +  V A+D D   N  +++ L ++          + F +N +TG I   
Sbjct: 1104 SVQEGPSPHGLIGTVKASDRDSLNNGVLSFILLTD---------GKYFSVNSRTGEIINL 1154

Query: 537  KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT--ANIMEDA 594
              LDRE  + ++L V   D G P L+ TT + I+V DVNDN P F     T   N+    
Sbjct: 1155 VALDREEQAQHVLRVMVTDQGRPRLNTTTTIHITVTDVNDNRPQFTHMPSTKELNVWAVI 1214

Query: 595  LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654
             V + V  + A D D G NG + + +   D + G F ID  SG ++            + 
Sbjct: 1215 PVNSVVISMFAKDLDAGENGTVKFSM--TDNQLGHFSIDSLSGDVKVTSQFSSNPQMRYT 1272

Query: 655  LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
            L+ VA D G  P   T +VHI++  ++     F+S    F + E+  +GT IG +     
Sbjct: 1273 LRVVATDNGLFPLEETAVVHIQVYVLDQQKENFQSSFQHFTVLEDVGLGTIIGSLGV--- 1329

Query: 715  DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL 774
               P+  + YSI  G+ S  F +++  G    EL     LDYE   ++Y LV+RA + P 
Sbjct: 1330 SNAPDTELRYSIVEGNGSLQFGIKSSSG----ELYVAQHLDYE-VTQRYFLVVRAEAFPT 1384

Query: 775  WN-DVRVEILVTDVNDNAP 792
            +N  V   + + DVND+ P
Sbjct: 1385 FNVTVFAAVSILDVNDHNP 1403



 Score =  271 bits (665), Expect = 2e-70
 Identities = 228/785 (29%), Positives = 355/785 (45%), Gaps = 49/785 (6%)

Query: 134  ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG 193
            A + + + D NDN P F +  Y  +V E      N  + ++ ATD+D G N  I Y I+ 
Sbjct: 2123 ARVAITLQDINDNAPVFKQSYYRTAVWE--GQIHNTYVMQVLATDSDSGVNGQISYFIMD 2180

Query: 194  GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDN 253
            GN    F IDS+ G ++    LD E V SY+L+I+A+D G    + T  + + + DVNDN
Sbjct: 2181 GNHNNAFVIDSVRGILATNAVLDREIVSSYKLIIQAKDMGKAPLTGTCTVRVQVVDVNDN 2240

Query: 254  APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313
            +P    S+   +++EN+P+GY + RV A D D   +A  TY + +KD T        ID 
Sbjct: 2241 SPTI-PSMEAVTIAENLPLGYIVTRVIANDVDLSPSA--TYRLIEKDDTSR---SFAIDL 2294

Query: 314  RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373
             +G + T+  LD E Q+ Y L V A+D         A               F    Y+V
Sbjct: 2295 YTGIITTTKILDYEEQSVYTLKVQASDS---VHQTEAELSIQVLDVNDNSPVFSQESYQV 2351

Query: 374  ELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431
             L+E     T VV++ ATD D  ++ R+ Y +      G F I   NG   +   +PL++
Sbjct: 2352 LLSERTLADTFVVSVLATDKDSGKNGRVSYRLLSSPVGG-FYIDPDNGS--VFTNKPLNY 2408

Query: 432  KQERRYV-LTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
                  + L V A DSG  +      V I + D N+ AP F    Y  ++ ED  +G+T+
Sbjct: 2409 VANGNVLRLLVEARDSGDPNLFCVTSVDIEVADFNDNAPFFTQNSYQINIPEDVSVGSTL 2468

Query: 489  LVVSATDSDVGI-NAQITYSLSSEISNEAVAHHDQQFVINPQT---GAITTNKLLDRETM 544
            + + A D D    N  + Y + S                 P +   G +     LDRET 
Sbjct: 2469 ITLLAEDKDYSDENTHLEYLIISGNDERRFCLEVVSIQAEPHSRTVGQLVLCDTLDRETT 2528

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
              Y LTVT  D G+  L+ +T V + V+D+NDN P F    Y A + E++ VG  + QV 
Sbjct: 2529 DAYSLTVTVTDRGINPLNSSTVVSVKVLDINDNAPAFSSPEYHAQVSENSPVGLVLVQVS 2588

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            A D D+G NG I Y +      +G   +D ++GVI+ N  LD E      L   A D GT
Sbjct: 2589 AYDPDLGANGTITYNI-ISGNSKGLITVDSSTGVIKVNGTLDYEEDTKLTLTVQASDWGT 2647

Query: 665  PPQS--STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
                  S  +V+I + D ND+ P F        +SEN P  T +  + A D D G   ++
Sbjct: 2648 SDDKKVSFAVVYILVLDENDNSPFFMFPTYNCSVSENLPAFTPVCTVHAVDEDAGTFGLL 2707

Query: 723  HYSIKG----GDDSNSFSLETRQGSD--KAELVTMVDLDYESPRKKYELVIRAASPPLWN 776
             YSI        DS++   +   G D    ++ T    DYE  R    +V          
Sbjct: 2708 SYSIVTPCFVDYDSSNPDKKEAFGIDPLTGDIHTKQTFDYEGDRNFCFVVEARDKGDQVA 2767

Query: 777  DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-----FGRVPAYDAD--VTDKLQY 829
             +RV I +  +++ +P+        N Y    P  P      G + A D D  +   ++Y
Sbjct: 2768 TLRVRIEIEGIDEFSPIFTQ-----NVYHFSLPANPKVGQSIGYLMAMDHDGGLDGLVEY 2822

Query: 830  RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889
             ++S   ++   +N+T G + +S   N+   + + +    T+ +  + +  +L  R  T 
Sbjct: 2823 SLVS--PSSFFNVNKTNGCLFVS---NSVYQRQSPISNETTEDLIVLASSPKLDSRSSTC 2877

Query: 890  EMLLN 894
             +++N
Sbjct: 2878 HVIVN 2882



 Score =  257 bits (629), Expect = 4e-66
 Identities = 242/828 (29%), Positives = 364/828 (43%), Gaps = 60/828 (7%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F IDG +G + T   LDRE+  +Y     AT     +         + + + D NDN+P 
Sbjct: 72  FEIDGDTGIISTAVVLDRERTDKYE-FAAATLTGEVIK--------VSIQVTDVNDNFPI 122

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG-- 207
           F  K   ++V E +S        +  A D D G      Y I  G  +  F ++  S   
Sbjct: 123 FPVKIIHLNVSE-LSPPGTRFELE-GAQDKDEGDYGTQGYRITDGEMRELFKVEIRSNGV 180

Query: 208 -----DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLF 262
                D+ L   LD E    Y   I A DGG P ++   Q  I + D NDN P F  S +
Sbjct: 181 GMFNLDLVLQTRLDREIADFYNFTIEAFDGGVPPKTGQLQAQITVLDENDNQPVFNQSEY 240

Query: 263 QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322
              + EN  +   + ++ A DAD G N ++ Y +  +    N      I   SG +  + 
Sbjct: 241 HAVILENATLMTPVCQIFATDADLGSNGQVIYGINRRQSDPNEFF--IIGSSSGIISVNK 298

Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX----XXXFMPGQYEVELAED 378
            LD E ++ Y+L+VTA D G  P S+                     F+      E++E 
Sbjct: 299 HLDYENESYYELIVTAWDSGIQPESSNTFVSIKVLNVNDNPPNISVLFLNEAGAPEVSEG 358

Query: 379 EPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG-RGLITVAQPLDFKQER 435
                 V  +  +D D  +  ++   + GG+  G FS+ S +    ++ V  PLD + + 
Sbjct: 359 AGFEDYVARIAVSDPDLGDVKKIDVLLQGGD--GMFSLRSMDDFLYVLCVDGPLDREIKD 416

Query: 436 RYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
            Y LTV+A+D G    S     QI +TD N+  PVF    Y  S+ ED  +GT V  V A
Sbjct: 417 LYELTVTASDYGCPPLSSVITFQIQVTDVNDNPPVFHQTIYEESIDEDVRVGTAVFRVKA 476

Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553
           TD D+G +++I YS+   + +E        F I+P  G ITT   LD E        V A
Sbjct: 477 TDKDLGGDSEIIYSI---VQSEQKC----PFNIDPTLGVITTAAALDHERERELRFLVVA 529

Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613
            DGG PSLS T  V I V DVNDN+P+F Q+ Y A + E   VGT + QV A DAD    
Sbjct: 530 SDGGSPSLSSTATVIIHVEDVNDNKPIFPQKFYNATVKEHTAVGTCILQVTAIDADGAEF 589

Query: 614 GRIHYEL----DPKDREEGSFVIDPASGVIRTNKALDRES-VATHDL--KA---VAIDGG 663
           G + Y L      KD     F I+  +G I  ++ +D E+ + T DL  KA   V++   
Sbjct: 590 GSVQYFLYDGFSGKD-VHPFFHINSVTGNICVSQDIDYEAGLLTFDLLIKAEDQVSLSFV 648

Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
               SS   VHI IED+ND+ PVF        +S ++  GT +  + A D D G    + 
Sbjct: 649 KDGFSSQTFVHIGIEDVNDNAPVFNPGKYVTSVSVHAQPGTELLNVYASDQDAGNYGKIT 708

Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR---AASPPLWNDVRV 780
           Y ++ GD +  F+++   GS     ++   +   S   K  +  R     S     ++ V
Sbjct: 709 YELQPGDSATLFTMDQSTGS---VYLSSSLMQLRSSSVKLSVSARDGGGMSAAYPANITV 765

Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAY-DADVTDKLQYRILSGNNAN 838
            IL +D      + +  Q  F+  +D  PVG   G V A   A+  + + Y I SG+   
Sbjct: 766 NILQSD--QPPALFQKAQYTFSISEDA-PVGSSVGLVQAITPANSVEVVSYVISSGDPQG 822

Query: 839 LILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886
              ++  TG +  +  L+        + +    G   I +  Q++V +
Sbjct: 823 FFSIDSQTGIINTAQPLDHESISYVILNIQFHTGTLPIHSSAQVNVSI 870



 Score =  227 bits (554), Expect = 4e-57
 Identities = 187/648 (28%), Positives = 298/648 (45%), Gaps = 40/648 (6%)

Query: 52   IGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA 111
            I +N  + Y +  V A+ ++   +              F ID  +G + T   LD E+ +
Sbjct: 2252 IAENLPLGYIVTRVIANDVDLSPSATYRLIEKDDTSRSFAIDLYTGIITTTKILDYEEQS 2311

Query: 112  RYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVI 171
             YT+ V+A+D        LS      + ++D NDN P FS+++Y V + E  ++ D  V+
Sbjct: 2312 VYTLKVQASDSVHQTEAELS------IQVLDVNDNSPVFSQESYQVLLSER-TLADTFVV 2364

Query: 172  AKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDY-EQVRSYRLVIRAQ 230
            + + ATD D G N  + Y ++       F ID  +G V   K L+Y       RL++ A+
Sbjct: 2365 S-VLATDKDSGKNGRVSYRLLSSPVG-GFYIDPDNGSVFTNKPLNYVANGNVLRLLVEAR 2422

Query: 231  DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVN 289
            D G P+    T + I + D NDNAP F  + +Q ++ E+V +G +++ + A D D    N
Sbjct: 2423 DSGDPNLFCVTSVDIEVADFNDNAPFFTQNSYQINIPEDVSVGSTLITLLAEDKDYSDEN 2482

Query: 290  AELTYTMTDKDYTGNVDL---PITIDPRS---GWVYTSGQLDRETQAKYQLLVTATDGGD 343
              L Y +   +      L    I  +P S   G +     LDRET   Y L VT TD G 
Sbjct: 2483 THLEYLIISGNDERRFCLEVVSIQAEPHSRTVGQLVLCDTLDRETTDAYSLTVTVTDRGI 2542

Query: 344  PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHY 401
             P +++                F   +Y  +++E+ P G  +V ++A D D   +  + Y
Sbjct: 2543 NPLNSSTVVSVKVLDINDNAPAFSSPEYHAQVSENSPVGLVLVQVSAYDPDLGANGTITY 2602

Query: 402  EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT----AMVQI 457
             I  GN++G   IT  +  G+I V   LD++++ +  LTV A+D G   D     A+V I
Sbjct: 2603 NIISGNSKG--LITVDSSTGVIKVNGTLDYEEDTKLTLTVQASDWGTSDDKKVSFAVVYI 2660

Query: 458  NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI---SN 514
             + D N+ +P F    Y  SV E+ P  T V  V A D D G    ++YS+ +      +
Sbjct: 2661 LVLDENDNSPFFMFPTYNCSVSENLPAFTPVCTVHAVDEDAGTFGLLSYSIVTPCFVDYD 2720

Query: 515  EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
             +     + F I+P TG I T +  D E    +   V ARD G      T  V I +  +
Sbjct: 2721 SSNPDKKEAFGIDPLTGDIHTKQTFDYEGDRNFCFVVEARDKG--DQVATLRVRIEIEGI 2778

Query: 575  NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634
            ++  P+F Q +Y  ++  +  VG S+  + A D D GL+G + Y L         F ++ 
Sbjct: 2779 DEFSPIFTQNVYHFSLPANPKVGQSIGYLMAMDHDGGLDGLVEYSL---VSPSSFFNVNK 2835

Query: 635  ASG-VIRTNKALDRES----VATHDLKAVAIDGGTPPQSST--VIVHI 675
             +G +  +N    R+S      T DL  +A       +SST  VIV+I
Sbjct: 2836 TNGCLFVSNSVYQRQSPISNETTEDLIVLASSPKLDSRSSTCHVIVNI 2883



 Score =  158 bits (383), Expect = 2e-36
 Identities = 134/491 (27%), Positives = 219/491 (44%), Gaps = 35/491 (7%)

Query: 5    FCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIG-KNAEVEYTI 62
            FC+    I V D ND++P F    Y+ ++ E  S G+T++TL A D+D   +N  +EY I
Sbjct: 2430 FCVTSVDIEVADFNDNAPFFTQNSYQINIPEDVSVGSTLITLLAEDKDYSDENTHLEYLI 2489

Query: 63   ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122
              ++ +    ++            +   R  G+   L+   +LDRE    Y++ V  TD+
Sbjct: 2490 --ISGN----DERRFCLEVVSIQAEPHSRTVGQ---LVLCDTLDRETTDAYSLTVTVTDR 2540

Query: 123  ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
                 + L+S+  + V ++D NDN P FS   Y   V E+  V    V+ ++ A D D+G
Sbjct: 2541 GI---NPLNSSTVVSVKVLDINDNAPAFSSPEYHAQVSENSPV--GLVLVQVSAYDPDLG 2595

Query: 183  ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS--PSRSNT 240
            AN  I Y II GN++   ++DS +G + +  TLDYE+     L ++A D G+    + + 
Sbjct: 2596 ANGTITYNIISGNSKGLITVDSSTGVIKVNGTLDYEEDTKLTLTVQASDWGTSDDKKVSF 2655

Query: 241  TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK- 299
              + I + D NDN+P F    +  SVSEN+P    +  V A D D G    L+Y++    
Sbjct: 2656 AVVYILVLDENDNSPFFMFPTYNCSVSENLPAFTPVCTVHAVDEDAGTFGLLSYSIVTPC 2715

Query: 300  --DY-TGNVDL--PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354
              DY + N D      IDP +G ++T    D E    +  +V A D GD  + AT     
Sbjct: 2716 FVDYDSSNPDKKEAFGIDPLTGDIHTKQTFDYEGDRNFCFVVEARDKGD--QVATLRVRI 2773

Query: 355  XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRF 412
                       F    Y   L  +   G  +  L A D D   D  + Y +   ++   F
Sbjct: 2774 EIEGIDEFSPIFTQNVYHFSLPANPKVGQSIGYLMAMDHDGGLDGLVEYSLVSPSS--FF 2831

Query: 413  SITSQNG-----RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAP 467
            ++   NG       +     P+  +     ++  S+     RS T  V +NI+       
Sbjct: 2832 NVNKTNGCLFVSNSVYQRQSPISNETTEDLIVLASSPKLDSRSSTCHVIVNISSTTKALA 2891

Query: 468  VFENAPYTASV 478
              + + +TA++
Sbjct: 2892 SADFSVHTATL 2902



 Score =  107 bits (258), Expect = 3e-21
 Identities = 97/308 (31%), Positives = 134/308 (43%), Gaps = 21/308 (6%)

Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554
           D   G+ A+ T S    IS    +   + F I+  TG I+T  +LDRE    Y       
Sbjct: 44  DIRAGLPAK-TQSSGFFISESRDSEVFRDFEIDGDTGIISTAVVLDRERTDKYEFAAATL 102

Query: 555 DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614
            G      +   V I V DVNDN P+F  ++   N+ E +  GT     GA D D G  G
Sbjct: 103 TG------EVIKVSIQVTDVNDNFPIFPVKIIHLNVSELSPPGTRFELEGAQDKDEGDYG 156

Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTN------KALDRESVATHDLKAVAIDGGTPPQS 668
              Y +   +  E   V   ++GV   N        LDRE    ++    A DGG PP++
Sbjct: 157 TQGYRITDGEMRELFKVEIRSNGVGMFNLDLVLQTRLDREIADFYNFTIEAFDGGVPPKT 216

Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-K 727
             +   I + D ND+ PVF        I EN+ + T + +I A D D G N  V Y I +
Sbjct: 217 GQLQAQITVLDENDNQPVFNQSEYHAVILENATLMTPVCQIFATDADLGSNGQVIYGINR 276

Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILV 784
              D N F +    GS    +     LDYE+    YEL++ A      P  ++  V I V
Sbjct: 277 RQSDPNEFFI---IGSSSGIISVNKHLDYEN-ESYYELIVTAWDSGIQPESSNTFVSIKV 332

Query: 785 TDVNDNAP 792
            +VNDN P
Sbjct: 333 LNVNDNPP 340



 Score = 44.4 bits (100), Expect = 0.046
 Identities = 49/151 (32%), Positives = 65/151 (43%), Gaps = 11/151 (7%)

Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751
           L+  + E  P  T +G+IRA  P +  ++   + I    DS  F  +     D   + T 
Sbjct: 28  LSLSVEEGLPAKTIVGDIRAGLPAKTQSS--GFFISESRDSEVFR-DFEIDGDTGIISTA 84

Query: 752 VDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811
           V LD E    KYE    AA+      ++V I VTDVNDN P+    +II  N  +  P G
Sbjct: 85  VVLDRER-TDKYEF---AAATLTGEVIKVSIQVTDVNDNFPIF-PVKIIHLNVSELSPPG 139

Query: 812 P-FGRVPAYDADVTD--KLQYRILSGNNANL 839
             F    A D D  D     YRI  G    L
Sbjct: 140 TRFELEGAQDKDEGDYGTQGYRITDGEMREL 170


>UniRef50_Q4SRZ9 Cluster: Chromosome 18 SCAF14485, whole genome
            shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 18
            SCAF14485, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 3280

 Score =  334 bits (820), Expect = 3e-89
 Identities = 261/869 (30%), Positives = 412/869 (47%), Gaps = 59/869 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V D ND  PVF    Y ASV E    G  V  + ATD D  +NA V Y+        L
Sbjct: 1645 VEVADVNDQPPVFSQSVYNASVAENKDPGEPVARVSATDGDSEENAVVWYS--------L 1696

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             P               ++F I+  +G + T + LDRE+   +T+ V+A D        L
Sbjct: 1697 LPGPGY-----------ELFSINPDTGLITTASYLDREQQHGFTLRVQARDSGPRP---L 1742

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S+TAT+  +++DDNDN P F + ++ +S+ E++       I   +A+D D+G N  I Y+
Sbjct: 1743 SATATVLCSVLDDNDNPPAFMQSSFRISLPENLPPG---AIHTAQASDPDLGENGTILYS 1799

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I+G +    F+++S SG VS  K LD E+ ++Y L I+A+D G    S++TQL + + D 
Sbjct: 1800 IVGEDCAGCFTVNSRSGVVSTTKVLDREEKQNYTLTIQARDYGPTPLSSSTQLQLVLLDR 1859

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDNAP F    +Q SVSE +P G  ++RV A+D DEG N  +TY++T+    G      +
Sbjct: 1860 NDNAPSFSRKSYQASVSEGLPPGAEVLRVSAFDPDEGPNGRVTYSLTEDSSQG----AFS 1915

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDG-GDPPRSATATXXXXXXXXXXXXXXFMPG 369
            +D  +G + T+G LDRE++A+Y L   ATDG    P ++ A+                  
Sbjct: 1916 VDSLTGVIRTTGPLDRESRAQYTLRAVATDGCTQGPLTSVASVTVQVEDVNDNVPICDQN 1975

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
                 ++    P   V T+TA D+D+      +    +    F I  + G   +      
Sbjct: 1976 PVNAWVSARTLPNQIVATVTAEDSDQGENGTIQFALSDEENLFDINRETGEISVRRRVRA 2035

Query: 430  DFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
             F   R+  + VS       + T +V I++    N    F N  Y A++ E++  G  V 
Sbjct: 2036 GF-SGRKLEVMVSDRGRPVLTSTCLVFIHL-KGENEGLQFTNKVYNATIKENSGAGILVT 2093

Query: 490  VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK--LLDRETMSGY 547
             V A+  + G    + Y++ S   NE     +  F IN  TG I   K   LD E +S +
Sbjct: 2094 KVEAS-GEAGSRQSVVYTIFS--GNE-----NSLFSINHHTGEIRVQKDYALDFE-LSPH 2144

Query: 548  LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
            +  V   D G+ +      V I ++DVNDN P F++  Y   + E     T V Q+ A+D
Sbjct: 2145 IHLVVLADNGLQTTH--CRVSIHLLDVNDNAPRFERSSYRTAVWEGQAHNTYVMQMFASD 2202

Query: 608  ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
            AD G+NG+I Y +   D  E +F++D   G++ T+  LDRE   ++ L   A D G PP 
Sbjct: 2203 ADSGINGQIEYSIVSGDPNE-AFILDSVRGILATSIPLDREITPSYKLVLQAADQGDPPL 2261

Query: 668  SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
            SST  V +++ D+ND+ P          I+EN P G T+ ++ A+D D   ++ + YS+ 
Sbjct: 2262 SSTATVRVQVVDVNDNSPAI-PHMEPVVIAENRPAGHTVTQVTANDVD--LSSTIRYSLS 2318

Query: 728  GGDDSNS-FSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRAASPPLWNDVRVEILVT 785
            G     S F++    G     +V++   LDYE  + +Y L + A+         V++ V 
Sbjct: 2319 GNSSLGSPFAINQYTG-----VVSLTRALDYEE-QAEYTLTVLASDSLHQTSGEVKVQVL 2372

Query: 786  DVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLN 843
            D+NDNAPV  +  +Q+  +       +         D+    ++ YR+LS       +  
Sbjct: 2373 DLNDNAPVFSEDSYQVDLSELATADTLVLSVSATDRDSGPNGEITYRLLSSPLQGFYIQA 2432

Query: 844  ETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            ++    T  P   T    L  + V   DG
Sbjct: 2433 DSGAIFTNKPIKATANGNLIHLLVEAKDG 2461



 Score =  327 bits (803), Expect = 3e-87
 Identities = 271/894 (30%), Positives = 421/894 (47%), Gaps = 56/894 (6%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI------E 63
            Q+ +LD ND+ PVF +      V E A  G+ +    A D D G+N  V YTI       
Sbjct: 1515 QVFLLDVNDNRPVF-ISAVSVQVMEDAEVGSLLHRFVAKDGDEGENGLVSYTILTGNKKG 1573

Query: 64   LVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQA 123
            + T +    +            V ++  +    G L   ++LD E    + ++V+A D  
Sbjct: 1574 MFTLEGNTGKMPLFCLHPLCFSVLNLSCLHFSPGLLFLASALDYESQRLHRLIVEAVDHG 1633

Query: 124  SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183
             P    LSST T  V + D ND  P FS+  Y  SV E+    + PV A++ ATD D   
Sbjct: 1634 LP---SLSSTQTFTVEVADVNDQPPVFSQSVYNASVAENKDPGE-PV-ARVSATDGDSEE 1688

Query: 184  NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
            N+ + Y+++ G     FSI+  +G ++    LD EQ   + L ++A+D G    S T  +
Sbjct: 1689 NAVVWYSLLPGPGYELFSINPDTGLITTASYLDREQQHGFTLRVQARDSGPRPLSATATV 1748

Query: 244  LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
            L ++ D NDN P F  S F+ S+ EN+P G +I   QA D D G N  + Y++  +D  G
Sbjct: 1749 LCSVLDDNDNPPAFMQSSFRISLPENLPPG-AIHTAQASDPDLGENGTILYSIVGEDCAG 1807

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
                  T++ RSG V T+  LDRE +  Y L + A D G  P S++              
Sbjct: 1808 ----CFTVNSRSGVVSTTKVLDREEKQNYTLTIQARDYGPTPLSSSTQLQLVLLDRNDNA 1863

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRG 421
              F    Y+  ++E  PPG  V+ ++A D DE  + R+ Y +T  +++G FS+ S    G
Sbjct: 1864 PSFSRKSYQASVSEGLPPGAEVLRVSAFDPDEGPNGRVTYSLTEDSSQGAFSVDSLT--G 1921

Query: 422  LITVAQPLDFKQERRYVLTVSATD---SGGRSDTAMVQINITDANNYAPVFENAPYTASV 478
            +I    PLD +   +Y L   ATD    G  +  A V + + D N+  P+ +  P  A V
Sbjct: 1922 VIRTTGPLDRESRAQYTLRAVATDGCTQGPLTSVASVTVQVEDVNDNVPICDQNPVNAWV 1981

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
                     V  V+A DSD G N  I ++LS E         +  F IN +TG I+  + 
Sbjct: 1982 SARTLPNQIVATVTAEDSDQGENGTIQFALSDE---------ENLFDINRETGEISVRRR 2032

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            + R   SG  L V   D G P L+ T  V I +   N+    F  ++Y A I E++  G 
Sbjct: 2033 V-RAGFSGRKLEVMVSDRGRPVLTSTCLVFIHLKGENEGLQ-FTNKVYNATIKENSGAGI 2090

Query: 599  SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK--ALDRESVATHDLK 656
             V++V A+  + G    + Y +     E   F I+  +G IR  K  ALD E ++ H   
Sbjct: 2091 LVTKVEAS-GEAGSRQSVVYTIF-SGNENSLFSINHHTGEIRVQKDYALDFE-LSPHIHL 2147

Query: 657  AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
             V  D G       V +H+   D+ND+ P FE       + E     T + ++ A D D 
Sbjct: 2148 VVLADNGLQTTHCRVSIHLL--DVNDNAPRFERSSYRTAVWEGQAHNTYVMQMFASDADS 2205

Query: 717  GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPP 773
            G N  + YSI  GD + +F L++ +G     L T + LD E     Y+LV++AA    PP
Sbjct: 2206 GINGQIEYSIVSGDPNEAFILDSVRGI----LATSIPLDREI-TPSYKLVLQAADQGDPP 2260

Query: 774  LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRIL 832
            L +   V + V DVNDN+P +   + +     +  P G    +V A D D++  ++Y  L
Sbjct: 2261 LSSTATVRVQVVDVNDNSPAIPHMEPVV--IAENRPAGHTVTQVTANDVDLSSTIRYS-L 2317

Query: 833  SGNNA--NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884
            SGN++  +   +N+ TG ++L+  L+       T+ V  +D +++    +++ V
Sbjct: 2318 SGNSSLGSPFAINQYTGVVSLTRALDYEEQAEYTLTVLASDSLHQTSGEVKVQV 2371



 Score =  317 bits (779), Expect = 2e-84
 Identities = 242/804 (30%), Positives = 397/804 (49%), Gaps = 77/804 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V D ND+ P+ +     A V         V T+ A D D G+N  +++         L
Sbjct: 1960 VQVEDVNDNVPICDQNPVNAWVSARTLPNQIVATVTAEDSDQGENGTIQFA--------L 2011

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            + E+             ++F I+  +G +  R  + R   +   + V  +D+  PV   L
Sbjct: 2012 SDEE-------------NLFDINRETGEISVRRRV-RAGFSGRKLEVMVSDRGRPV---L 2054

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +ST  + +++  +N+   QF+ K Y  ++ E+       ++ K++A+  + G+  ++ Y 
Sbjct: 2055 TSTCLVFIHLKGENEGL-QFTNKVYNATIKENSGA--GILVTKVEAS-GEAGSRQSVVYT 2110

Query: 191  IIGGNTQMQFSIDSLSGDVSLVK--TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            I  GN    FSI+  +G++ + K   LD+E      LV+ A +G    ++   ++ I++ 
Sbjct: 2111 IFSGNENSLFSINHHTGEIRVQKDYALDFELSPHIHLVVLADNG---LQTTHCRVSIHLL 2167

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            DVNDNAPRF  S ++ +V E       ++++ A DAD G+N ++ Y++     +G+ +  
Sbjct: 2168 DVNDNAPRFERSSYRTAVWEGQAHNTYVMQMFASDADSGINGQIEYSIV----SGDPNEA 2223

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
              +D   G + TS  LDRE    Y+L++ A D GDPP S+TAT               +P
Sbjct: 2224 FILDSVRGILATSIPLDREITPSYKLVLQAADQGDPPLSSTATVRVQVVDVNDNSPA-IP 2282

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGR-FSITSQNGRGLITVAQ 427
                V +AE+ P G  V  +TA D D  + + Y ++G ++ G  F+I    G  ++++ +
Sbjct: 2283 HMEPVVIAENRPAGHTVTQVTANDVDLSSTIRYSLSGNSSLGSPFAINQYTG--VVSLTR 2340

Query: 428  PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
             LD++++  Y LTV A+DS  ++ +  V++ + D N+ APVF    Y   + E A   T 
Sbjct: 2341 ALDYEEQAEYTLTVLASDSLHQT-SGEVKVQVLDLNDNAPVFSEDSYQVDLSELATADTL 2399

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
            VL VSATD D G N +ITY L S           Q F I   +GAI TNK + + T +G 
Sbjct: 2400 VLSVSATDRDSGPNGEITYRLLSSPL--------QGFYIQADSGAIFTNKPI-KATANGN 2450

Query: 548  L--LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
            L  L V A+DGG P+LS    V++ ++D ND+ P F Q++Y+  I ED     ++  + A
Sbjct: 2451 LIHLLVEAKDGGDPALSSVASVDVQILDTNDHVPTFHQEVYSLTIPEDTPTDATLLTLSA 2510

Query: 606  TDADVG-LNGRIHYELDPKDREEGSFVID----PAS------GVIRTNKALDRESVATHD 654
             D D    N  + Y +  +  EE  F ++    P        G +    ALDRE+  ++ 
Sbjct: 2511 EDQDWSPANTHLDYAIT-QGNEERRFCLEVRLVPIENQWRNVGKLVLCNALDRETTDSYV 2569

Query: 655  LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
            L     D G PP +S+ +V + + D ND+ PVF S      +SE+SP GT + ++ A DP
Sbjct: 2570 LTVSVSDRGDPPLNSSAVVMLTVADRNDNAPVFSSTEYHAQVSESSPRGTRLVQVSARDP 2629

Query: 715  DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL 774
            D G N++V + I  G+    + L+   G     L     LDYE    KY L +RA+    
Sbjct: 2630 DLGANSLVRFDIISGNSKGHYKLDPESGL----LAVNQSLDYEQD-PKYILTVRASDGGE 2684

Query: 775  WNDVR------VEILVTDVNDNAP 792
            +++        V I V D NDN+P
Sbjct: 2685 FSEKHQVAFAVVFITVLDENDNSP 2708



 Score =  312 bits (766), Expect = 9e-83
 Identities = 263/882 (29%), Positives = 402/882 (45%), Gaps = 50/882 (5%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           I  +I V D NDHSPVF  +     + E +  G+      A D+D     E E+  +   
Sbjct: 102 IKVRIEVKDVNDHSPVFPSEGLNLEISEVSPPGSRFKLEGAKDED-----EDEFGTQGYR 156

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
                 E+            Q +      S  L+  + LDRE+   Y++ ++A D   P 
Sbjct: 157 IRESEMEERFHLDHHRSGSGQHL------SLDLVLMSRLDREEQDFYSLTIEAFDGGVPP 210

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
               + T  + ++++D+NDN P F++  Y  SV ED  +  +PV  ++ ATD D+G N  
Sbjct: 211 R---TGTLQLRIHVLDENDNPPVFNQTEYHASVPEDAPLM-SPV-CQVHATDLDLGDNGR 265

Query: 187 IRYAIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
           I Y I    +     FSI+  SG V + K LDYE    + L++ A D G+    ++T + 
Sbjct: 266 ITYEINRRQSDPDRVFSINRTSGVVYVNKPLDYEAQAFHELIVSATDNGAQPEHSSTFVG 325

Query: 245 INIRDVNDNAPRFYTSLFQES----VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
           + + ++ND++P        E+    VSE   +G  + R+   D D      +  T+   D
Sbjct: 326 VRVLNINDHSPSISVLFLSETGDAAVSEAAGLGDFVARISVSDPDFQ-EERVAVTLEGDD 384

Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
             G   L  T D     +Y S  LDRE +  Y+L V A+D G PP S+            
Sbjct: 385 --GKFTLKQTADFLYA-LYVSADLDREEKDLYELKVRASDLGSPPLSSEVVFLLRVTDAN 441

Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQN 418
                F    Y V + ED P G+ ++ L A DADE  +  + Y I   N     SI  ++
Sbjct: 442 DCHPQFEKDAYTVSVPEDVPQGSSLIQLQARDADEGPNGAVRYSILRSNQDRLVSIEPES 501

Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTA 476
           G  L+  A PLD +   +    V A D G    S TA V + + D N+  PVF+   Y A
Sbjct: 502 G--LVATAAPLDRESLEQLWFLVVAADGGEPSLSSTATVTVQVLDVNDNEPVFQRQLYGA 559

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
           SV E + +G+  L V ATD+D      + YSLS     +        F ++PQ+G +  +
Sbjct: 560 SVPEHSAVGSCFLQVVATDADSPAFGTLLYSLSDGFDGQ---DQHPLFHVHPQSGELCVS 616

Query: 537 KLLDRET-MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
           + +DR++  + + L + A D G   LS  T V + V D+NDN PVF    YT +I   A 
Sbjct: 617 QDIDRDSGQTVHDLLIRAEDPG--GLSAQTYVHVEVEDLNDNAPVFNPDEYTVSISGHAQ 674

Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655
            G  V  V ATD D G  G++ Y + P D     F +DP +G +     L     A+  L
Sbjct: 675 PGAEVLNVIATDRDSGRFGQVTYGIIPGDMSS-LFDVDPQTGTLTLTSPLTDLGAASLQL 733

Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
              A DG     +   +V + +     +P VF     TF ++E++  GTT+G + A  P 
Sbjct: 734 LLTAQDGEGVMSAKPAVVTVHVLHSARAPAVFHQSRYTFTVAEDATPGTTVGTVEAVTPA 793

Query: 716 -EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP-- 772
            EG +A V Y I  GD    FS+  R G     + +   LD+E  +    LVI++ S   
Sbjct: 794 AEGFSASVSYRISSGDPQGFFSIHPRSGV----ISSTKPLDHEL-QPNVLLVIQSYSDAS 848

Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYR 830
           P+++  +V I VTDVNDNAPV        +  ++  P        A+DAD     +++YR
Sbjct: 849 PVYSTTQVNIAVTDVNDNAPVFLRASDAVSVSQNVLPGTVLYIAHAHDADSGSNGRVRYR 908

Query: 831 ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            L  +      ++   G++TL   L  +  +   +EV   DG
Sbjct: 909 -LRNDRFGTFGIDRNLGTVTLIQSLLGSRQQSYHLEVVAEDG 949



 Score =  308 bits (756), Expect = 2e-81
 Identities = 235/760 (30%), Positives = 359/760 (47%), Gaps = 73/760 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I++LD ND++P FE   Y  +V EG +  T V+ + A+D D G N ++EY+I  V+ D  
Sbjct: 2164 IHLLDVNDNAPRFERSSYRTAVWEGQAHNTYVMQMFASDADSGINGQIEYSI--VSGD-- 2219

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             P +A              F +D   G L T   LDRE    Y ++++A DQ  P    L
Sbjct: 2220 -PNEA--------------FILDSVRGILATSIPLDREITPSYKLVLQAADQGDPP---L 2261

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            SSTAT+ V ++D NDN P        V  +   +      + ++ A D D+  +S IRY+
Sbjct: 2262 SSTATVRVQVVDVNDNSPAIPHMEPVVIAENRPA---GHTVTQVTANDVDL--SSTIRYS 2316

Query: 191  IIGGNTQ-MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            + G ++    F+I+  +G VSL + LDYE+   Y L + A D        + ++ + + D
Sbjct: 2317 LSGNSSLGSPFAINQYTGVVSLTRALDYEEQAEYTLTVLASDS---LHQTSGEVKVQVLD 2373

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            +NDNAP F    +Q  +SE       ++ V A D D G N E+TY +      G      
Sbjct: 2374 LNDNAPVFSEDSYQVDLSELATADTLVLSVSATDRDSGPNGEITYRLLSSPLQG-----F 2428

Query: 310  TIDPRSGWVYTSGQLDRETQAKY-QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
             I   SG ++T+  +          LLV A DGGDP  S+ A+              F  
Sbjct: 2429 YIQADSGAIFTNKPIKATANGNLIHLLVEAKDGGDPALSSVASVDVQILDTNDHVPTFHQ 2488

Query: 369  GQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQ-------- 417
              Y + + ED P    ++TL+A D D    +  L Y IT GN   RF +  +        
Sbjct: 2489 EVYSLTIPEDTPTDATLLTLSAEDQDWSPANTHLDYAITQGNEERRFCLEVRLVPIENQW 2548

Query: 418  NGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYT 475
               G + +   LD +    YVLTVS +D G    + +A+V + + D N+ APVF +  Y 
Sbjct: 2549 RNVGKLVLCNALDRETTDSYVLTVSVSDRGDPPLNSSAVVMLTVADRNDNAPVFSSTEYH 2608

Query: 476  ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
            A V E +P GT ++ VSA D D+G N+ + + +   IS  +  H+     ++P++G +  
Sbjct: 2609 AQVSESSPRGTRLVQVSARDPDLGANSLVRFDI---ISGNSKGHYK----LDPESGLLAV 2661

Query: 536  NKLLDRETMSGYLLTVTARDGGVPSLSDTTD---VEISVVDVNDNEPVFKQQLYTANIME 592
            N+ LD E    Y+LTV A DGG  S         V I+V+D NDN P F       +++E
Sbjct: 2662 NQSLDYEQDPKYILTVRASDGGEFSEKHQVAFAVVFITVLDENDNSPHFVFSTVNCSVLE 2721

Query: 593  DALVGTSVSQVGATDADVGLNGRIHYE-LDP--KDREEGS------FVIDPASGVIRTNK 643
            +    T    V A D D+G  G++ Y  L P   D + GS      F IDP +G + T +
Sbjct: 2722 NLPAFTHTCSVHAVDNDLGSYGQLTYSILSPCFLDYDSGSPEKKEAFAIDPLTGDVHTRQ 2781

Query: 644  ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703
              D E  + +     A D G   +++TV V + I  +++  P+F      F +  +S  G
Sbjct: 2782 TFDYERESEYCFVVEARDKGG--KTATVRVQVSIRGVDEFSPIFTQKQYHFLLPGHSKPG 2839

Query: 704  TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
              +G + A D D G + +V YS+     S  FS+    GS
Sbjct: 2840 DVVGFVMAMDHDRGVDGIVGYSLV--SSSPFFSVNKTTGS 2877



 Score =  304 bits (746), Expect = 2e-80
 Identities = 257/853 (30%), Positives = 385/853 (45%), Gaps = 68/853 (7%)

Query: 11   INVLDCNDHSP----VFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            + VL+ NDHSP    +F  +  +A+V E A  G  V  +  +D D  +            
Sbjct: 326  VRVLNINDHSPSISVLFLSETGDAAVSEAAGLGDFVARISVSDPDFQEER---------V 376

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
            A TL  +D           +           AL   A LDRE+   Y + V+A+D  SP 
Sbjct: 377  AVTLEGDDGKFTLKQTADFLY----------ALYVSADLDREEKDLYELKVRASDLGSPP 426

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
               LSS     + + D ND +PQF +  YTVSV ED  V     + +++A DAD G N A
Sbjct: 427  ---LSSEVVFLLRVTDANDCHPQFEKDAYTVSVPED--VPQGSSLIQLQARDADEGPNGA 481

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            +RY+I+  N     SI+  SG V+    LD E +     ++ A DGG PS S+T  + + 
Sbjct: 482  VRYSILRSNQDRLVSIEPESGLVATAAPLDRESLEQLWFLVVAADGGEPSLSSTATVTVQ 541

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            + DVNDN P F   L+  SV E+  +G   ++V A DAD      L Y+++D  + G   
Sbjct: 542  VLDVNDNEPVFQRQLYGASVPEHSAVGSCFLQVVATDADSPAFGTLLYSLSD-GFDGQDQ 600

Query: 307  LPIT-IDPRSGWVYTSGQLDRET-QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
             P+  + P+SG +  S  +DR++ Q  + LL+ A D G    SA                
Sbjct: 601  HPLFHVHPQSGELCVSQDIDRDSGQTVHDLLIRAEDPGG--LSAQTYVHVEVEDLNDNAP 658

Query: 365  XFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGL 422
             F P +Y V ++    PG  V+ + ATD D     ++ Y I  G+    F +  Q G   
Sbjct: 659  VFNPDEYTVSISGHAQPGAEVLNVIATDRDSGRFGQVTYGIIPGDMSSLFDVDPQTGT-- 716

Query: 423  ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480
            +T+  PL         L ++A D  G   +  A+V +++  +     VF  + YT +V E
Sbjct: 717  LTLTSPLTDLGAASLQLLLTAQDGEGVMSAKPAVVTVHVLHSARAPAVFHQSRYTFTVAE 776

Query: 481  DAPIGTTVLVVSA-TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
            DA  GTTV  V A T +  G +A ++Y +SS             F I+P++G I++ K L
Sbjct: 777  DATPGTTVGTVEAVTPAAEGFSASVSYRISS-------GDPQGFFSIHPRSGVISSTKPL 829

Query: 540  DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
            D E     LL + +     P  S TT V I+V DVNDN PVF +     ++ ++ L GT 
Sbjct: 830  DHELQPNVLLVIQSYSDASPVYS-TTQVNIAVTDVNDNAPVFLRASDAVSVSQNVLPGTV 888

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
            +    A DAD G NGR+ Y L  ++   G+F ID   G +   ++L      ++ L+ VA
Sbjct: 889  LYIAHAHDADSGSNGRVRYRL--RNDRFGTFGIDRNLGTVTLIQSLLGSRQQSYHLEVVA 946

Query: 660  IDGGTPPQSSTVIVHIKIE-DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
             DGG P QSS + + + ++    +    FE+      I E     + + ++       GP
Sbjct: 947  EDGGEPAQSSGLSLSVSVDRSAAEDSLAFETLVYQVEIGEGYRKDSRVIQL-------GP 999

Query: 719  NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIRAASPPLWN- 776
                   ++ GD S   S      S    +V    LDYE+    ++ ++  AA P L N 
Sbjct: 1000 R------LRLGDGSRLSSRSVSDSSQVRVVVLAHSLDYETQSAFRFRVLASAAEPSLANT 1053

Query: 777  --DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSG 834
                 V + V DVNDNAPV       F   +   P G  G V A D D     Q   +  
Sbjct: 1054 TATAAVTVSVLDVNDNAPVFSRDLYYFTVSEAPSPQGLVGTVSAADKDSGRNAQLSYILL 1113

Query: 835  NNANLILLNETTG 847
            ++     +N  TG
Sbjct: 1114 SDGKFFRINAKTG 1126



 Score =  291 bits (714), Expect = 2e-76
 Identities = 254/884 (28%), Positives = 402/884 (45%), Gaps = 75/884 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            Q+ +LD ND++P F  + Y+ASV EG   G  VL + A D D G N  V Y++       
Sbjct: 1853 QLVLLDRNDNAPSFSRKSYQASVSEGLPPGAEVLRVSAFDPDEGPNGRVTYSLT------ 1906

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
               ED+           Q  F +D  +G + T   LDRE  A+YT+   ATD  +     
Sbjct: 1907 ---EDSS----------QGAFSVDSLTGVIRTTGPLDRESRAQYTLRAVATDGCT--QGP 1951

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            L+S A++ V + D NDN P   +      V        N ++A + A D+D G N  I++
Sbjct: 1952 LTSVASVTVQVEDVNDNVPICDQNPVNAWV--SARTLPNQIVATVTAEDSDQGENGTIQF 2009

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            A+   + +  F I+  +G++S V+          +L +   D G P  ++T  + I+++ 
Sbjct: 2010 AL--SDEENLFDINRETGEIS-VRRRVRAGFSGRKLEVMVSDRGRPVLTSTCLVFIHLKG 2066

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
             N+   +F   ++  ++ EN   G  + +V+A   + G    + YT+    ++GN +   
Sbjct: 2067 ENEGL-QFTNKVYNATIKENSGAGILVTKVEA-SGEAGSRQSVVYTI----FSGNENSLF 2120

Query: 310  TIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
            +I+  +G +       LD E      L+V A +G    ++                  F 
Sbjct: 2121 SINHHTGEIRVQKDYALDFELSPHIHLVVLADNG---LQTTHCRVSIHLLDVNDNAPRFE 2177

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITV 425
               Y   + E +   T V+ + A+DAD   + ++ Y I  G+    F + S   RG++  
Sbjct: 2178 RSSYRTAVWEGQAHNTYVMQMFASDADSGINGQIEYSIVSGDPNEAFILDSV--RGILAT 2235

Query: 426  AQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
            + PLD +    Y L + A D G    S TA V++ + D N+ +P   +      + E+ P
Sbjct: 2236 SIPLDREITPSYKLVLQAADQGDPPLSSTATVRVQVVDVNDNSPAIPHME-PVVIAENRP 2294

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
             G TV  V+A  +DV +++ I YSLS    N ++      F IN  TG ++  + LD E 
Sbjct: 2295 AGHTVTQVTA--NDVDLSSTIRYSLS---GNSSLG---SPFAINQYTGVVSLTRALDYEE 2346

Query: 544  MSGYLLTVTARDGGVPSLSDTT-DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
             + Y LTV A D    SL  T+ +V++ V+D+NDN PVF +  Y  ++ E A   T V  
Sbjct: 2347 QAEYTLTVLASD----SLHQTSGEVKVQVLDLNDNAPVFSEDSYQVDLSELATADTLVLS 2402

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT-HDLKAVAID 661
            V ATD D G NG I Y L     +   F I   SG I TNK +   +      L   A D
Sbjct: 2403 VSATDRDSGPNGEITYRLLSSPLQ--GFYIQADSGAIFTNKPIKATANGNLIHLLVEAKD 2460

Query: 662  GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP-NA 720
            GG P  SS   V ++I D ND  P F  +  +  I E++P   T+  + A D D  P N 
Sbjct: 2461 GGDPALSSVASVDVQILDTNDHVPTFHQEVYSLTIPEDTPTDATLLTLSAEDQDWSPANT 2520

Query: 721  VVHYSIKGGDDSNSFSLETR------QGSDKAELVTMVDLDYESPRKKYELVIRAA---S 771
             + Y+I  G++   F LE R      Q  +  +LV    LD E+    Y L +  +    
Sbjct: 2521 HLDYAITQGNEERRFCLEVRLVPIENQWRNVGKLVLCNALDRET-TDSYVLTVSVSDRGD 2579

Query: 772  PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADV--TDKLQ 828
            PPL +   V + V D NDNAPV    +       +  P G    +V A D D+     ++
Sbjct: 2580 PPLNSSAVVMLTVADRNDNAPVFSSTE-YHAQVSESSPRGTRLVQVSARDPDLGANSLVR 2638

Query: 829  YRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            + I+SGN+     L+  +G + ++  L+        + V  +DG
Sbjct: 2639 FDIISGNSKGHYKLDPESGLLAVNQSLDYEQDPKYILTVRASDG 2682



 Score =  288 bits (707), Expect = 1e-75
 Identities = 220/679 (32%), Positives = 336/679 (49%), Gaps = 47/679 (6%)

Query: 88  DVFR---IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDN 144
           DVFR   ID  +G + T   LDRE   +Y  +      A+P  + +     + + + D N
Sbjct: 62  DVFRDLEIDADTGLISTAVVLDRESRRQYDFVA-----ATPTGEMIK----VRIEVKDVN 112

Query: 145 DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS 204
           D+ P F  +   + + E         +   K  D D        Y I     + +F +D 
Sbjct: 113 DHSPVFPSEGLNLEISEVSPPGSRFKLEGAKDEDEDEFGTQG--YRIRESEMEERFHLDH 170

Query: 205 --------LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256
                   LS D+ L+  LD E+   Y L I A DGG P R+ T QL I++ D NDN P 
Sbjct: 171 HRSGSGQHLSLDLVLMSRLDREEQDFYSLTIEAFDGGVPPRTGTLQLRIHVLDENDNPPV 230

Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316
           F  + +  SV E+ P+   + +V A D D G N  +TY +  +    + D   +I+  SG
Sbjct: 231 FNQTEYHASVPEDAPLMSPVCQVHATDLDLGDNGRITYEINRRQ--SDPDRVFSINRTSG 288

Query: 317 WVYTSGQLDRETQAKYQLLVTATDGG-DPPRSAT---ATXXXXXXXXXXXXXXFMPGQYE 372
            VY +  LD E QA ++L+V+ATD G  P  S+T                   F+    +
Sbjct: 289 VVYVNKPLDYEAQAFHELIVSATDNGAQPEHSSTFVGVRVLNINDHSPSISVLFLSETGD 348

Query: 373 VELAEDEPPGTPVVTLTATDAD-EDNRLHYEITGGNTRGRFSIT-SQNGRGLITVAQPLD 430
             ++E    G  V  ++ +D D ++ R+   + G +  G+F++  + +    + V+  LD
Sbjct: 349 AAVSEAAGLGDFVARISVSDPDFQEERVAVTLEGDD--GKFTLKQTADFLYALYVSADLD 406

Query: 431 FKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
            +++  Y L V A+D G    S   +  + +TDAN+  P FE   YT SV ED P G+++
Sbjct: 407 REEKDLYELKVRASDLGSPPLSSEVVFLLRVTDANDCHPQFEKDAYTVSVPEDVPQGSSL 466

Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
           + + A D+D G N  + YS+    SN+     D+   I P++G + T   LDRE++    
Sbjct: 467 IQLQARDADEGPNGAVRYSILR--SNQ-----DRLVSIEPESGLVATAAPLDRESLEQLW 519

Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
             V A DGG PSLS T  V + V+DVNDNEPVF++QLY A++ E + VG+   QV ATDA
Sbjct: 520 FLVVAADGGEPSLSSTATVTVQVLDVNDNEPVFQRQLYGASVPEHSAVGSCFLQVVATDA 579

Query: 609 DVGLNGRIHYEL-DPKDREEGS--FVIDPASGVIRTNKALDRESVAT-HDLKAVAIDGGT 664
           D    G + Y L D  D ++    F + P SG +  ++ +DR+S  T HDL   A D G 
Sbjct: 580 DSPAFGTLLYSLSDGFDGQDQHPLFHVHPQSGELCVSQDIDRDSGQTVHDLLIRAEDPG- 638

Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
              S+   VH+++ED+ND+ PVF  D  T  IS ++  G  +  + A D D G    V Y
Sbjct: 639 -GLSAQTYVHVEVEDLNDNAPVFNPDEYTVSISGHAQPGAEVLNVIATDRDSGRFGQVTY 697

Query: 725 SIKGGDDSNSFSLETRQGS 743
            I  GD S+ F ++ + G+
Sbjct: 698 GIIPGDMSSLFDVDPQTGT 716



 Score =  284 bits (696), Expect = 3e-74
 Identities = 254/928 (27%), Positives = 408/928 (43%), Gaps = 70/928 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI----ELVT 66
            ++VLD ND++PVF    Y  +V E  S    V T+ A D+D G+NA++ Y +    +   
Sbjct: 1061 VSVLDVNDNAPVFSRDLYYFTVSEAPSPQGLVGTVSAADKDSGRNAQLSYILLSDGKFFR 1120

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
             +    +            ++    +   SG ++   +L+RE  +++T+ V  TDQ  P 
Sbjct: 1121 INAKTGQSPWQLRCFSVAWMRPNALVSP-SGEIINWVALNREHHSQHTLKVMVTDQGHP- 1178

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI--SVTDNPVIAKIKATDADVGAN 184
              RL++TAT+H+ + D NDN PQF     +  V+  I   +    ++A + A D D G N
Sbjct: 1179 --RLNATATVHILVTDTNDNTPQFMHLPASKEVNVQIWAEIPAGSLVANMFAKDLDAGEN 1236

Query: 185  SAIRYAIIGGN--TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
              + +++   +      F ID  +G++   +         Y L + A DGG+P   +   
Sbjct: 1237 GTVTFSLASEDEGEPPHFEIDGETGNIRTTEHFTRNTRPFYTLTVCASDGGAPPLEHVAV 1296

Query: 243  LLINIRDVNDNAPRFYTSLFQE-SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
            + + +        R    L +  +V E+  +  + V   A   DEG      Y++++ D 
Sbjct: 1297 VHVQVHGSEAVDGRAEHPLVRRFTVREDAEL--ATVIGSARVPDEG---RFRYSISEGD- 1350

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
             G+V     ID  SG +Y +  LD E  A+Y L+V A   G  P +  +           
Sbjct: 1351 -GSVQ--FGIDASSGDIYVNQPLDYEAAAQYVLVVRAEGAGLAPGANASVLVSVMVEDAN 1407

Query: 362  XXXXFMPGQYE-VELAEDEPPGTPVVTLTATDAD---EDNRLHY------EITGGNTRGR 411
                + P +   + L+ED   G+      A DAD    ++ + Y      ++T  +TR  
Sbjct: 1408 DHTPWFPDKMVLLGLSEDATVGSLAFAFQARDADGTFPNSAVRYGLTYDPKVTDSSTRFP 1467

Query: 412  FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSD-----TAMVQINITDANNYA 466
            F +    G   +TV  PLD +    +  TV+ATD   R +     T   Q+ + D N+  
Sbjct: 1468 FQMNPYTGS--LTVTAPLDRETTSSFAFTVTATDQARRKEERKQATVAAQVFLLDVNDNR 1525

Query: 467  PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL-----SSEISNEAVAHHD 521
            PVF +A  +  V EDA +G+ +    A D D G N  ++Y++         + E      
Sbjct: 1526 PVFISA-VSVQVMEDAEVGSLLHRFVAKDGDEGENGLVSYTILTGNKKGMFTLEGNTGKM 1584

Query: 522  QQFVINP-------------QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568
              F ++P               G +     LD E+   + L V A D G+PSLS T    
Sbjct: 1585 PLFCLHPLCFSVLNLSCLHFSPGLLFLASALDYESQRLHRLIVEAVDHGLPSLSSTQTFT 1644

Query: 569  ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG 628
            + V DVND  PVF Q +Y A++ E+   G  V++V ATD D   N  + Y L P    E 
Sbjct: 1645 VEVADVNDQPPVFSQSVYNASVAENKDPGEPVARVSATDGDSEENAVVWYSLLPGPGYE- 1703

Query: 629  SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688
             F I+P +G+I T   LDRE      L+  A D G  P S+T  V   + D ND+PP F 
Sbjct: 1704 LFSINPDTGLITTASYLDREQQHGFTLRVQARDSGPRPLSATATVLCSVLDDNDNPPAFM 1763

Query: 689  SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAEL 748
                   + EN P G  I   +A DPD G N  + YSI G D +  F++ +R G     +
Sbjct: 1764 QSSFRISLPENLPPG-AIHTAQASDPDLGENGTILYSIVGEDCAGCFTVNSRSG----VV 1818

Query: 749  VTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYK 805
             T   LD E  ++ Y L I+A      PL +  ++++++ D NDNAP         +  +
Sbjct: 1819 STTKVLDREE-KQNYTLTIQARDYGPTPLSSSTQLQLVLLDRNDNAPSFSRKSYQASVSE 1877

Query: 806  DCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLA 863
               P     RV A+D D     ++ Y +   ++     ++  TG +  +  L+       
Sbjct: 1878 GLPPGAEVLRVSAFDPDEGPNGRVTYSLTEDSSQGAFSVDSLTGVIRTTGPLDRESRAQY 1937

Query: 864  TMEVSVTDGVNEIKAMMQLSVRLITEEM 891
            T+    TDG  +       SV +  E++
Sbjct: 1938 TLRAVATDGCTQGPLTSVASVTVQVEDV 1965



 Score =  248 bits (607), Expect = 2e-63
 Identities = 238/817 (29%), Positives = 360/817 (44%), Gaps = 88/817 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V D ND  P FE   Y  SV E    G++++ L+A D D G N  V Y+I     D L
Sbjct: 435  LRVTDANDCHPQFEKDAYTVSVPEDVPQGSSLIQLQARDADEGPNGAVRYSILRSNQDRL 494

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                                 I+  SG + T A LDRE + +   LV A D   P    L
Sbjct: 495  -------------------VSIEPESGLVATAAPLDRESLEQLWFLVVAADGGEP---SL 532

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            SSTAT+ V ++D NDN P F  + Y  SV E  +V       ++ ATDAD  A   + Y+
Sbjct: 533  SSTATVTVQVLDVNDNEPVFQRQLYGASVPEHSAV--GSCFLQVVATDADSPAFGTLLYS 590

Query: 191  IIGG-NTQMQ---FSIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGGSPSRSNTTQLLI 245
            +  G + Q Q   F +   SG++ + + +D +  ++ + L+IRA+D G  S    T + +
Sbjct: 591  LSDGFDGQDQHPLFHVHPQSGELCVSQDIDRDSGQTVHDLLIRAEDPGGLSAQ--TYVHV 648

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
             + D+NDNAP F    +  S+S +   G  ++ V A D D G   ++TY +   D +   
Sbjct: 649  EVEDLNDNAPVFNPDEYTVSISGHAQPGAEVLNVIATDRDSGRFGQVTYGIIPGDMSSLF 708

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
            D    +DP++G +  +  L     A  QLL+TA DG     +  A               
Sbjct: 709  D----VDPQTGTLTLTSPLTDLGAASLQLLLTAQDGEGVMSAKPAVVTVHVLHSARAPAV 764

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTA-TDADE--DNRLHYEITGGNTRGRFSITSQNGRGL 422
            F   +Y   +AED  PGT V T+ A T A E     + Y I+ G+ +G FSI  ++G  +
Sbjct: 765  FHQSRYTFTVAEDATPGTTVGTVEAVTPAAEGFSASVSYRISSGDPQGFFSIHPRSG--V 822

Query: 423  ITVAQPLDFKQERRYVLTV-SATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
            I+  +PLD + +   +L + S +D+     T  V I +TD N+ APVF  A    SV ++
Sbjct: 823  ISSTKPLDHELQPNVLLVIQSYSDASPVYSTTQVNIAVTDVNDNAPVFLRASDAVSVSQN 882

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
               GT + +  A D+D G N ++ Y L ++            F I+   G +T  + L  
Sbjct: 883  VLPGTVLYIAHAHDADSGSNGRVRYRLRNDRFGT--------FGIDRNLGTVTLIQSLLG 934

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVV-DVNDNEPVFKQQLYTANIMEDALVGTSV 600
                 Y L V A DGG P+ S    + +SV     ++   F+  +Y   I E     + V
Sbjct: 935  SRQQSYHLEVVAEDGGEPAQSSGLSLSVSVDRSAAEDSLAFETLVYQVEIGEGYRKDSRV 994

Query: 601  SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK--AV 658
             Q+G     +G   R    L  +   + S V      V+    +LD E+ +    +  A 
Sbjct: 995  IQLGPR-LRLGDGSR----LSSRSVSDSSQV-----RVVVLAHSLDYETQSAFRFRVLAS 1044

Query: 659  AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE-NSPIGTTIGEIRAHDPDEG 717
            A +      ++T  V + + D+ND+ PVF  D   F +SE  SP G  +G + A D D G
Sbjct: 1045 AAEPSLANTTATAAVTVSVLDVNDNAPVFSRDLYYFTVSEAPSPQG-LVGTVSAADKDSG 1103

Query: 718  PNAVVHYSIKGGDDSNSFSLETRQG--------------------SDKAELVTMVDL--D 755
             NA + Y +    D   F +  + G                    S   E++  V L  +
Sbjct: 1104 RNAQLSYILL--SDGKFFRINAKTGQSPWQLRCFSVAWMRPNALVSPSGEIINWVALNRE 1161

Query: 756  YESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP 792
            + S      +V     P L     V ILVTD NDN P
Sbjct: 1162 HHSQHTLKVMVTDQGHPRLNATATVHILVTDTNDNTP 1198



 Score =  248 bits (606), Expect = 2e-63
 Identities = 183/648 (28%), Positives = 301/648 (46%), Gaps = 38/648 (5%)

Query: 52   IGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA 111
            I +N    +T+  VTA+ ++              +   F I+  +G +    +LD E+ A
Sbjct: 2289 IAENRPAGHTVTQVTANDVDLSSTIRYSLSGNSSLGSPFAINQYTGVVSLTRALDYEEQA 2348

Query: 112  RYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVI 171
             YT+ V A+D     S        + V ++D NDN P FSE +Y V + E    T + ++
Sbjct: 2349 EYTLTVLASDSLHQTS------GEVKVQVLDLNDNAPVFSEDSYQVDLSE--LATADTLV 2400

Query: 172  AKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLD-YEQVRSYRLVIRAQ 230
              + ATD D G N  I Y ++    Q  F I + SG +   K +          L++ A+
Sbjct: 2401 LSVSATDRDSGPNGEITYRLLSSPLQ-GFYIQADSGAIFTNKPIKATANGNLIHLLVEAK 2459

Query: 231  DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVN 289
            DGG P+ S+   + + I D ND+ P F+  ++  ++ E+ P   +++ + A D D    N
Sbjct: 2460 DGGDPALSSVASVDVQILDTNDHVPTFHQEVYSLTIPEDTPTDATLLTLSAEDQDWSPAN 2519

Query: 290  AELTYTMTDKDYTGNVDLPITIDP------RSGWVYTSGQLDRETQAKYQLLVTATDGGD 343
              L Y +T  +      L + + P        G +     LDRET   Y L V+ +D GD
Sbjct: 2520 THLDYAITQGNEERRFCLEVRLVPIENQWRNVGKLVLCNALDRETTDSYVLTVSVSDRGD 2579

Query: 344  PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHY 401
            PP +++A               F   +Y  +++E  P GT +V ++A D D   ++ + +
Sbjct: 2580 PPLNSSAVVMLTVADRNDNAPVFSSTEYHAQVSESSPRGTRLVQVSARDPDLGANSLVRF 2639

Query: 402  EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT-----AMVQ 456
            +I  GN++G + +  ++  GL+ V Q LD++Q+ +Y+LTV A+D G  S+      A+V 
Sbjct: 2640 DIISGNSKGHYKLDPES--GLLAVNQSLDYEQDPKYILTVRASDGGEFSEKHQVAFAVVF 2697

Query: 457  INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI---S 513
            I + D N+ +P F  +    SV E+ P  T    V A D+D+G   Q+TYS+ S      
Sbjct: 2698 ITVLDENDNSPHFVFSTVNCSVLENLPAFTHTCSVHAVDNDLGSYGQLTYSILSPCFLDY 2757

Query: 514  NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
            +       + F I+P TG + T +  D E  S Y   V ARD G    + T  V++S+  
Sbjct: 2758 DSGSPEKKEAFAIDPLTGDVHTRQTFDYERESEYCFVVEARDKG--GKTATVRVQVSIRG 2815

Query: 574  VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633
            V++  P+F Q+ Y   +   +  G  V  V A D D G++G + Y L         F ++
Sbjct: 2816 VDEFSPIFTQKQYHFLLPGHSKPGDVVGFVMAMDHDRGVDGIVGYSL---VSSSPFFSVN 2872

Query: 634  PASG-VIRTNKALDRESVATHDLKAVAIDGGTPPQSS---TVIVHIKI 677
              +G V  +     R      DL  + +  G+P  SS   T +V I I
Sbjct: 2873 KTTGSVFVSEPVYRRRGSHGEDLVKLLVSAGSPKLSSRTTTCVVFINI 2920



 Score =  241 bits (591), Expect = 1e-61
 Identities = 231/849 (27%), Positives = 366/849 (43%), Gaps = 84/849 (9%)

Query: 104  SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI 163
            SLD E  + +   V A+  A P     ++TA + V+++D NDN P FS   Y  +V E  
Sbjct: 1028 SLDYETQSAFRFRVLAS-AAEPSLANTTATAAVTVSVLDVNDNAPVFSRDLYYFTVSE-- 1084

Query: 164  SVTDNPVIAKIKATDADVGANSAIRYAIIG-----------GNTQMQ---FSID------ 203
            + +   ++  + A D D G N+ + Y ++            G +  Q   FS+       
Sbjct: 1085 APSPQGLVGTVSAADKDSGRNAQLSYILLSDGKFFRINAKTGQSPWQLRCFSVAWMRPNA 1144

Query: 204  --SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261
              S SG++     L+ E    + L +   D G P  + T  + I + D NDN P+F    
Sbjct: 1145 LVSPSGEIINWVALNREHHSQHTLKVMVTDQGHPRLNATATVHILVTDTNDNTPQFMHLP 1204

Query: 262  FQESVS----ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317
              + V+      +P G  +  + A D D G N  +T+++  +D  G       ID  +G 
Sbjct: 1205 ASKEVNVQIWAEIPAGSLVANMFAKDLDAGENGTVTFSLASED-EGEPP-HFEIDGETGN 1262

Query: 318  VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM-PGQYEVELA 376
            + T+    R T+  Y L V A+DGG PP    A                  P      + 
Sbjct: 1263 IRTTEHFTRNTRPFYTLTVCASDGGAPPLEHVAVVHVQVHGSEAVDGRAEHPLVRRFTVR 1322

Query: 377  EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436
            ED    T + +    D   + R  Y I+ G+   +F I + +G   I V QPLD++   +
Sbjct: 1323 EDAELATVIGSARVPD---EGRFRYSISEGDGSVQFGIDASSGD--IYVNQPLDYEAAAQ 1377

Query: 437  YVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
            YVL V A  +G   G + + +V + + DAN++ P F +      + EDA +G+      A
Sbjct: 1378 YVLVVRAEGAGLAPGANASVLVSVMVEDANDHTPWFPDKMVLLGLSEDATVGSLAFAFQA 1437

Query: 494  TDSDVGI-NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552
             D+D    N+ + Y L+ +      +     F +NP TG++T    LDRET S +  TVT
Sbjct: 1438 RDADGTFPNSAVRYGLTYD-PKVTDSSTRFPFQMNPYTGSLTVTAPLDRETTSSFAFTVT 1496

Query: 553  ARDGG---VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
            A D           T   ++ ++DVNDN PVF   + +  +MEDA VG+ + +  A D D
Sbjct: 1497 ATDQARRKEERKQATVAAQVFLLDVNDNRPVFISAV-SVQVMEDAEVGSLLHRFVAKDGD 1555

Query: 610  VGLNGRIHYELDPKDRE-----EGS------FVIDP-------------ASGVIRTNKAL 645
             G NG + Y +   +++     EG+      F + P             + G++    AL
Sbjct: 1556 EGENGLVSYTILTGNKKGMFTLEGNTGKMPLFCLHPLCFSVLNLSCLHFSPGLLFLASAL 1615

Query: 646  DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
            D ES   H L   A+D G P  SST    +++ D+ND PPVF        ++EN   G  
Sbjct: 1616 DYESQRLHRLIVEAVDHGLPSLSSTQTFTVEVADVNDQPPVFSQSVYNASVAENKDPGEP 1675

Query: 706  IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYE 764
            +  + A D D   NAVV YS+  G     FS+      D   + T   LD E        
Sbjct: 1676 VARVSATDGDSEENAVVWYSLLPGPGYELFSI----NPDTGLITTASYLDREQQHGFTLR 1731

Query: 765  LVIRAASP-PLWNDVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFPVGPFGRVPAYDA 821
            +  R + P PL     V   V D NDN P  +   F+I   +  +  P G      A D 
Sbjct: 1732 VQARDSGPRPLSATATVLCSVLDDNDNPPAFMQSSFRI---SLPENLPPGAIHTAQASDP 1788

Query: 822  DVTDK--LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKA 878
            D+ +   + Y I+  + A    +N  +G ++ +  L+    +  T+ +   D G   + +
Sbjct: 1789 DLGENGTILYSIVGEDCAGCFTVNSRSGVVSTTKVLDREEKQNYTLTIQARDYGPTPLSS 1848

Query: 879  MMQLSVRLI 887
              QL + L+
Sbjct: 1849 STQLQLVLL 1857



 Score =  187 bits (455), Expect = 4e-45
 Identities = 162/594 (27%), Positives = 265/594 (44%), Gaps = 64/594 (10%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ VLD ND++PVF    Y+  + E A++ T VL++ ATD+D G N E+ Y +       
Sbjct: 2368 KVQVLDLNDNAPVFSEDSYQVDLSELATADTLVLSVSATDRDSGPNGEITYRL------- 2420

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYT-VLVKATDQASPVSD 128
                            +Q  F I   SGA+ T   +          +LV+A D   P   
Sbjct: 2421 ------------LSSPLQG-FYIQADSGAIFTNKPIKATANGNLIHLLVEAKDGGDPA-- 2465

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG-ANSAI 187
             LSS A++ V I+D ND+ P F ++ Y++++ ED + TD  ++  + A D D   AN+ +
Sbjct: 2466 -LSSVASVDVQILDTNDHVPTFHQEVYSLTIPED-TPTDATLLT-LSAEDQDWSPANTHL 2522

Query: 188  RYAIIGGNTQMQFSIDSLS----------GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237
             YAI  GN + +F ++             G + L   LD E   SY L +   D G P  
Sbjct: 2523 DYAITQGNEERRFCLEVRLVPIENQWRNVGKLVLCNALDRETTDSYVLTVSVSDRGDPPL 2582

Query: 238  SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297
            +++  +++ + D NDNAP F ++ +   VSE+ P G  +V+V A D D G N+ + + + 
Sbjct: 2583 NSSAVVMLTVADRNDNAPVFSSTEYHAQVSESSPRGTRLVQVSARDPDLGANSLVRFDII 2642

Query: 298  DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD---PPRSATATXXX 354
              +  G+  L    DP SG +  +  LD E   KY L V A+DGG+     + A A    
Sbjct: 2643 SGNSKGHYKL----DPESGLLAVNQSLDYEQDPKYILTVRASDGGEFSEKHQVAFAVVFI 2698

Query: 355  XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITG------- 405
                       F+       + E+ P  T   ++ A D D  +  +L Y I         
Sbjct: 2699 TVLDENDNSPHFVFSTVNCSVLENLPAFTHTCSVHAVDNDLGSYGQLTYSILSPCFLDYD 2758

Query: 406  -GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANN 464
             G+   + +       G +   Q  D+++E  Y   V A D GG++ T  VQ++I   + 
Sbjct: 2759 SGSPEKKEAFAIDPLTGDVHTRQTFDYERESEYCFVVEARDKGGKTATVRVQVSIRGVDE 2818

Query: 465  YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524
            ++P+F    Y   +   +  G  V  V A D D G++  + YSL S             F
Sbjct: 2819 FSPIFTQKQYHFLLPGHSKPGDVVGFVMAMDHDRGVDGIVGYSLVSS---------SPFF 2869

Query: 525  VINPQTGAITTNKLLDRETMS-GYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577
             +N  TG++  ++ + R   S G  L       G P LS  T   +  ++++ +
Sbjct: 2870 SVNKTTGSVFVSEPVYRRRGSHGEDLVKLLVSAGSPKLSSRTTTCVVFINISSS 2923



 Score =  173 bits (422), Expect = 4e-41
 Identities = 149/501 (29%), Positives = 229/501 (45%), Gaps = 44/501 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIG-KNAEVEYTIELVTADT 69
            + +LD NDH P F  + Y  ++ E   +  T+LTL A DQD    N  ++Y I      T
Sbjct: 2474 VQILDTNDHVPTFHQEVYSLTIPEDTPTDATLLTLSAEDQDWSPANTHLDYAI------T 2527

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
               E+           +++ +R     G L+   +LDRE    Y + V  +D+  P    
Sbjct: 2528 QGNEERRFCLEVRLVPIENQWR---NVGKLVLCNALDRETTDSYVLTVSVSDRGDP---P 2581

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            L+S+A + + + D NDN P FS   Y   V E  S      + ++ A D D+GANS +R+
Sbjct: 2582 LNSSAVVMLTVADRNDNAPVFSSTEYHAQVSE--SSPRGTRLVQVSARDPDLGANSLVRF 2639

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ---LLIN 246
             II GN++  + +D  SG +++ ++LDYEQ   Y L +RA DGG  S  +      + I 
Sbjct: 2640 DIISGNSKGHYKLDPESGLLAVNQSLDYEQDPKYILTVRASDGGEFSEKHQVAFAVVFIT 2699

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK---DY-T 302
            + D NDN+P F  S    SV EN+P       V A D D G   +LTY++      DY +
Sbjct: 2700 VLDENDNSPHFVFSTVNCSVLENLPAFTHTCSVHAVDNDLGSYGQLTYSILSPCFLDYDS 2759

Query: 303  GNVDL--PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
            G+ +      IDP +G V+T    D E +++Y  +V A D G   ++AT           
Sbjct: 2760 GSPEKKEAFAIDPLTGDVHTRQTFDYERESEYCFVVEARDKGG--KTATVRVQVSIRGVD 2817

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQN 418
                 F   QY   L     PG  V  + A D D   D  + Y +   +    FS+    
Sbjct: 2818 EFSPIFTQKQYHFLLPGHSKPGDVVGFVMAMDHDRGVDGIVGYSLVSSSP--FFSVNKTT 2875

Query: 419  GRGLITVAQPLDFKQ----ERRYVLTVSATDS--GGRSDTAMVQINITDANNYAPVFENA 472
            G   + V++P+  ++    E    L VSA       R+ T +V INI+ +   A     A
Sbjct: 2876 GS--VFVSEPVYRRRGSHGEDLVKLLVSAGSPKLSSRTTTCVVFINISSS---AEALAGA 2930

Query: 473  PYTASVFEDAPIGTTVLVVSA 493
            P  A +     +G +++V+ A
Sbjct: 2931 PLDAHMLS---LGVSLVVILA 2948



 Score = 41.5 bits (93), Expect = 0.32
 Identities = 35/104 (33%), Positives = 52/104 (50%), Gaps = 13/104 (12%)

Query: 692 LTFYISENSPIGTTIGEIRA--HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV 749
           LT  + E  P GT +G++ A    P  G      + I    DS+ F  +    +D   + 
Sbjct: 25  LTLSVKEGLPAGTIVGDLGAVLSAPSTG------FFISESRDSDVFR-DLEIDADTGLIS 77

Query: 750 TMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPV 793
           T V LD ES R++Y+ V   A+ P    ++V I V DVND++PV
Sbjct: 78  TAVVLDRES-RRQYDFV---AATPTGEMIKVRIEVKDVNDHSPV 117


>UniRef50_A7S5N5 Cluster: Predicted protein; n=1; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 1610

 Score =  333 bits (818), Expect = 5e-89
 Identities = 242/790 (30%), Positives = 374/790 (47%), Gaps = 57/790 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +N+LD ND+ PVF+   Y A+V E AS G TVL ++A D D+  NA V Y+I  V+ +T 
Sbjct: 852  VNLLDVNDNDPVFDRDVYTANVSEDASPGLTVLKIRAVDNDLASNANVSYSI--VSGNT- 908

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F +D  +G +   + L+REK+  YT+ V + D  + V  R 
Sbjct: 909  ----------------GAAFHVDNVTGEIKLVSKLEREKITSYTLTVGSADGGA-VPRR- 950

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             STA + + ++D NDN P     T TV + E++       + K+  TD D   N  + Y 
Sbjct: 951  -STALVIIYVMDVNDNSPVCLHDTQTVRLLENLPA--GHFVVKVVTTDPDEVHNGRVEYN 1007

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            +    T   F +D  +G ++  + LD E + +Y L++ A++  S        + + + D 
Sbjct: 1008 L----TSDAFRVDPFTGIITTTRALDRESIPAYNLMVTARNSNSSDMEVNCSVHVIVMDT 1063

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            ND+ P F  + +  S  E  P+G ++ RV+A D D+G+NAE+ YT+  ++          
Sbjct: 1064 NDHTPSFTMARYYISTPETTPVGSTLFRVRAVDGDDGINAEVRYTLMGEESL------FR 1117

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX-XFMPG 369
            I+  +G V     LDRE +A+YQL V A D G P  +A +T               F   
Sbjct: 1118 INYTTGIVTLVSSLDRENKAQYQLEVEARDRGIPESNANSTTILIRVGDVNDNRPTFTHA 1177

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQ 427
             Y+  + E +  G     + A D DE+    + Y I GGNT   F+I +++G  + T+  
Sbjct: 1178 HYDGNVLEGQV-GAVAAIVVALDKDEEINADIVYSIIGGNTDNSFAINNKSG-SIYTLLH 1235

Query: 428  PLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
             LD +   RY+LTV A+D G    + +  V I++ D N+  P   N P      E+ P G
Sbjct: 1236 -LDRETTDRYILTVLASDRGEPAMNSSTNVTIHVNDVNDNKPNITNNPGVVVTRENTPPG 1294

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
            + V ++SA+D D G NA++ +S          A  D +F I P  G I     LDRE  +
Sbjct: 1295 SLVYILSASDLDEGSNARVAFS--------GYAVPDGKFSIKPN-GEIMVRDSLDREAQN 1345

Query: 546  GYLLTVTARDGGVPSL-SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
             ++    A D G P   S     +I + D NDN PVF    Y+ NI E+      + QV 
Sbjct: 1346 RFVFYAMATDSGQPPFNSSMVSFDILIADENDNNPVFDPVHYSVNISENGPSEEVIVQVN 1405

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            A++ D    G++ +++   D   G F I   +GVI T K LDRE V+  DL   A D G 
Sbjct: 1406 ASERD---EGKLLFKISSGD-PGGYFTIHNVTGVISTRKPLDREMVSRFDLTITAEDEGR 1461

Query: 665  PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
            P + +   V I + D ND  PV E       +SEN+ IG+ +  I A D D+  N  + Y
Sbjct: 1462 PSRMALGYVTIFVNDENDFAPVIEQCEQLVSVSENAHIGSAVASINAVDKDDPSNTKITY 1521

Query: 725  SI-KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEIL 783
            S+     +  +  L    GS    ++    L     +  Y + + A+         + + 
Sbjct: 1522 SVGNSAFNITTQRLPFSSGSRYRGIIITAGLLDRERQDNYNITVTASDGNHIATCNIIVR 1581

Query: 784  VTDVNDNAPV 793
            +TDVNDN+PV
Sbjct: 1582 ITDVNDNSPV 1591



 Score =  330 bits (812), Expect = 2e-88
 Identities = 263/881 (29%), Positives = 411/881 (46%), Gaps = 71/881 (8%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            I+  INVLD ND+ PV +   Y  S+ E  S G +++ L  TDQD G+NA + Y   +V+
Sbjct: 633  INVTINVLDSNDNIPVCDKVYYTISIPENTSVGQSLIHLNCTDQDSGENAHLLY--HMVS 690

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLD-REKVARYTVLVKATDQASP 125
              +                    F +D  +G +     LD  EK   +TV ++  D   P
Sbjct: 691  GHSK-------------------FVVDNVTGIMSLNKLLDFEEKPTVFTVAIEVIDHGRP 731

Query: 126  VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
                LS    ++V + + NDNYP F +  YT  + E     D+ ++  + A D D  +++
Sbjct: 732  P---LSLVVFVNVTVDNVNDNYPSFGQDNYTFWISEGDFAVDHAIVGVVSAHDLDADSSN 788

Query: 186  A-----IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS-- 238
                  ++Y +  GN+   F+ID  +G +  V +LD E +++Y   + AQD   P+R   
Sbjct: 789  CPLCGKLQYTL--GNSTGPFAIDKDTGVLRAVGSLDREGIKNYTFSVIAQD-SIPNRPLV 845

Query: 239  NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
            N T + +N+ DVNDN P F   ++  +VSE+   G ++++++A D D   NA ++Y++  
Sbjct: 846  NVTMVTVNLLDVNDNDPVFDRDVYTANVSEDASPGLTVLKIRAVDNDLASNANVSYSIV- 904

Query: 299  KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358
               +GN      +D  +G +    +L+RE    Y L V + DGG  PR +TA        
Sbjct: 905  ---SGNTGAAFHVDNVTGEIKLVSKLEREKITSYTLTVGSADGGAVPRRSTALVIIYVMD 961

Query: 359  XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITS 416
                    +     V L E+ P G  VV +  TD DE  + R+ Y +T    R       
Sbjct: 962  VNDNSPVCLHDTQTVRLLENLPAGHFVVKVVTTDPDEVHNGRVEYNLTSDAFR------V 1015

Query: 417  QNGRGLITVAQPLDFKQERRYVLTVSA--TDSGGRSDTAMVQINITDANNYAPVFENAPY 474
                G+IT  + LD +    Y L V+A  ++S        V + + D N++ P F  A Y
Sbjct: 1016 DPFTGIITTTRALDRESIPAYNLMVTARNSNSSDMEVNCSVHVIVMDTNDHTPSFTMARY 1075

Query: 475  TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
              S  E  P+G+T+  V A D D GINA++ Y+L  E         +  F IN  TG +T
Sbjct: 1076 YISTPETTPVGSTLFRVRAVDGDDGINAEVRYTLMGE---------ESLFRINYTTGIVT 1126

Query: 535  TNKLLDRETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593
                LDRE  + Y L V ARD G+P S +++T + I V DVNDN P F    Y  N++E 
Sbjct: 1127 LVSSLDRENKAQYQLEVEARDRGIPESNANSTTILIRVGDVNDNRPTFTHAHYDGNVLE- 1185

Query: 594  ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653
              VG   + V A D D  +N  I Y +      + SF I+  SG I T   LDRE+   +
Sbjct: 1186 GQVGAVAAIVVALDKDEEINADIVYSI-IGGNTDNSFAINNKSGSIYTLLHLDRETTDRY 1244

Query: 654  DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713
             L  +A D G P  +S+  V I + D+ND+ P   ++       EN+P G+ +  + A D
Sbjct: 1245 ILTVLASDRGEPAMNSSTNVTIHVNDVNDNKPNITNNPGVVVTRENTPPGSLVYILSASD 1304

Query: 714  PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK--KYELVIRAAS 771
             DEG NA V +S     D   FS++        E++    LD E+  +   Y +   +  
Sbjct: 1305 LDEGSNARVAFSGYAVPD-GKFSIK-----PNGEIMVRDSLDREAQNRFVFYAMATDSGQ 1358

Query: 772  PPLWND-VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYR 830
            PP  +  V  +IL+ D NDN PV        N  ++        +V A + D   KL ++
Sbjct: 1359 PPFNSSMVSFDILIADENDNNPVFDPVHYSVNISENGPSEEVIVQVNASERD-EGKLLFK 1417

Query: 831  ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            I SG+      ++  TG ++    L+  +     + ++  D
Sbjct: 1418 ISSGDPGGYFTIHNVTGVISTRKPLDREMVSRFDLTITAED 1458



 Score =  328 bits (806), Expect = 1e-87
 Identities = 272/864 (31%), Positives = 395/864 (45%), Gaps = 83/864 (9%)

Query: 15   DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
            D ND+SP+F    Y + + E    GT V+ + A D DIG NA V Y +           D
Sbjct: 421  DENDNSPIFSRALYSSPIYENEPPGTFVIQVSANDSDIGSNAMVSYAVL---------SD 471

Query: 75   AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134
            A              F+I+ ++G + T   LDRE +  + + V A+D A P+S    S  
Sbjct: 472  AEGHY--------QYFKINAKNGTITTSRRLDRENITTFRLRVTASDGA-PLSTIRVSVV 522

Query: 135  TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194
             + V ++D NDN P+F   +Y  SV E  +     ++  I A D D   N  I Y I  G
Sbjct: 523  DVVVTVLDINDNSPEFVRPSYNFSVIE--TALPGAILGIISAVDRDKDLNGNIVYIITEG 580

Query: 195  NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP-----SRSNTT-QLLINIR 248
            N +  F I + SG + L  TLD E V  + L + A D G       S  NTT  + IN+ 
Sbjct: 581  NVEGSFIIGARSGLLQLNHTLDREVVSKHSLRVTASDRGGEFMADGSSLNTTINVTINVL 640

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            D NDN P      +  S+ EN  +G S++ +   D D G NA L Y M     +G+    
Sbjct: 641  DSNDNIPVCDKVYYTISIPENTSVGQSLIHLNCTDQDSGENAHLLYHMV----SGH--SK 694

Query: 309  ITIDPRSGWVYTSGQLD-RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
              +D  +G +  +  LD  E    + + +   D G PP S                  F 
Sbjct: 695  FVVDNVTGIMSLNKLLDFEEKPTVFTVAIEVIDHGRPPLSLVVFVNVTVDNVNDNYPSFG 754

Query: 368  PGQYEVELAED----EPPGTPVVTLTATDADEDN-----RLHYEITGGNTRGRFSITSQN 418
               Y   ++E     +     VV+    DAD  N     +L Y  T GN+ G F+I    
Sbjct: 755  QDNYTFWISEGDFAVDHAIVGVVSAHDLDADSSNCPLCGKLQY--TLGNSTGPFAIDKDT 812

Query: 419  GRGLITVAQPLDFKQERRYVLTVSATDSGGRS---DTAMVQINITDANNYAPVFENAPYT 475
              G++     LD +  + Y  +V A DS       +  MV +N+ D N+  PVF+   YT
Sbjct: 813  --GVLRAVGSLDREGIKNYTFSVIAQDSIPNRPLVNVTMVTVNLLDVNDNDPVFDRDVYT 870

Query: 476  ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
            A+V EDA  G TVL + A D+D+  NA ++YS+ S   N   A H     ++  TG I  
Sbjct: 871  ANVSEDASPGLTVLKIRAVDNDLASNANVSYSIVS--GNTGAAFH-----VDNVTGEIKL 923

Query: 536  NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
               L+RE ++ Y LTV + DGG      T  V I V+DVNDN PV      T  ++E+  
Sbjct: 924  VSKLEREKITSYTLTVGSADGGAVPRRSTALVIIYVMDVNDNSPVCLHDTQTVRLLENLP 983

Query: 596  VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655
             G  V +V  TD D   NGR+ Y L        +F +DP +G+I T +ALDRES+  ++L
Sbjct: 984  AGHFVVKVVTTDPDEVHNGRVEYNL-----TSDAFRVDPFTGIITTTRALDRESIPAYNL 1038

Query: 656  KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS--ENSPIGTTIGEIRAHD 713
               A +  +        VH+ + D ND  P F      +YIS  E +P+G+T+  +RA D
Sbjct: 1039 MVTARNSNSSDMEVNCSVHVIVMDTNDHTPSF--TMARYYISTPETTPVGSTLFRVRAVD 1096

Query: 714  PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRAASP 772
             D+G NA V Y++ G  + + F +    G     +VT+V  LD E+ + +Y+L + A   
Sbjct: 1097 GDDGINAEVRYTLMG--EESLFRINYTTG-----IVTLVSSLDREN-KAQYQLEVEARDR 1148

Query: 773  PL----WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR-VPAYDAD--VTD 825
             +     N   + I V DVNDN P         N  +    VG     V A D D  +  
Sbjct: 1149 GIPESNANSTTILIRVGDVNDNRPTFTHAHYDGNVLEG--QVGAVAAIVVALDKDEEINA 1206

Query: 826  KLQYRILSGNNANLILLNETTGSM 849
             + Y I+ GN  N   +N  +GS+
Sbjct: 1207 DIVYSIIGGNTDNSFAINNKSGSI 1230



 Score =  327 bits (804), Expect = 2e-87
 Identities = 235/757 (31%), Positives = 359/757 (47%), Gaps = 44/757 (5%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            F ID  +G L    SLDRE +  YT  V A D  S  +  L +   + VN++D NDN P 
Sbjct: 806  FAIDKDTGVLRAVGSLDREGIKNYTFSVIAQD--SIPNRPLVNVTMVTVNLLDVNDNDPV 863

Query: 150  FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209
            F    YT +V ED S      + KI+A D D+ +N+ + Y+I+ GNT   F +D+++G++
Sbjct: 864  FDRDVYTANVSEDAS--PGLTVLKIRAVDNDLASNANVSYSIVSGNTGAAFHVDNVTGEI 921

Query: 210  SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269
             LV  L+ E++ SY L + + DGG+  R +T  ++I + DVNDN+P          + EN
Sbjct: 922  KLVSKLEREKITSYTLTVGSADGGAVPRRSTALVIIYVMDVNDNSPVCLHDTQTVRLLEN 981

Query: 270  VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329
            +P G+ +V+V   D DE  N  + Y +T   +         +DP +G + T+  LDRE+ 
Sbjct: 982  LPAGHFVVKVVTTDPDEVHNGRVEYNLTSDAF--------RVDPFTGIITTTRALDRESI 1033

Query: 330  AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389
              Y L+VTA +          +              F   +Y +   E  P G+ +  + 
Sbjct: 1034 PAYNLMVTARNSNSSDMEVNCSVHVIVMDTNDHTPSFTMARYYISTPETTPVGSTLFRVR 1093

Query: 390  ATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447
            A D D+  +  + Y + G  +  R + T+    G++T+   LD + + +Y L V A D G
Sbjct: 1094 AVDGDDGINAEVRYTLMGEESLFRINYTT----GIVTLVSSLDRENKAQYQLEVEARDRG 1149

Query: 448  ---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504
                 +++  + I + D N+  P F +A Y  +V E   +G    +V A D D  INA I
Sbjct: 1150 IPESNANSTTILIRVGDVNDNRPTFTHAHYDGNVLE-GQVGAVAAIVVALDKDEEINADI 1208

Query: 505  TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT 564
             YS+          + D  F IN ++G+I T   LDRET   Y+LTV A D G P+++ +
Sbjct: 1209 VYSIIG-------GNTDNSFAINNKSGSIYTLLHLDRETTDRYILTVLASDRGEPAMNSS 1261

Query: 565  TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624
            T+V I V DVNDN+P            E+   G+ V  + A+D D G N R+ +      
Sbjct: 1262 TNVTIHVNDVNDNKPNITNNPGVVVTRENTPPGSLVYILSASDLDEGSNARVAF--SGYA 1319

Query: 625  REEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP-QSSTVIVHIKIEDINDS 683
              +G F I P +G I    +LDRE+       A+A D G PP  SS V   I I D ND+
Sbjct: 1320 VPDGKFSIKP-NGEIMVRDSLDREAQNRFVFYAMATDSGQPPFNSSMVSFDILIADENDN 1378

Query: 684  PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
             PVF+    +  ISEN P    I ++ A + DEG    + + I  GD    F++    G 
Sbjct: 1379 NPVFDPVHYSVNISENGPSEEVIVQVNASERDEGK---LLFKISSGDPGGYFTIHNVTG- 1434

Query: 744  DKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQII 800
                + T   LD E    +++L I A     P       V I V D ND APV++  + +
Sbjct: 1435 ---VISTRKPLDREMV-SRFDLTITAEDEGRPSRMALGYVTIFVNDENDFAPVIEQCEQL 1490

Query: 801  FNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNA 837
             +  ++         + A D D     +     GN+A
Sbjct: 1491 VSVSENAHIGSAVASINAVDKDDPSNTKITYSVGNSA 1527



 Score =  314 bits (772), Expect = 2e-83
 Identities = 244/799 (30%), Positives = 380/799 (47%), Gaps = 65/799 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + VLD ND+SP F    Y  SV E A  G  +  + A D+D   N  + Y I        
Sbjct: 526  VTVLDINDNSPEFVRPSYNFSVIETALPGAILGIISAVDRDKDLNGNIVYII-------- 577

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV---S 127
                           V+  F I  RSG L    +LDRE V+++++ V A+D+        
Sbjct: 578  -----------TEGNVEGSFIIGARSGLLQLNHTLDREVVSKHSLRVTASDRGGEFMADG 626

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
              L++T  + +N++D NDN P   +  YT+S+ E+ SV  +  +  +  TD D G N+ +
Sbjct: 627  SSLNTTINVTINVLDSNDNIPVCDKVYYTISIPENTSVGQS--LIHLNCTDQDSGENAHL 684

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGGSPSRSNTTQLLIN 246
             Y ++ G++  +F +D+++G +SL K LD+E+  + + + I   D G P  S    + + 
Sbjct: 685  LYHMVSGHS--KFVVDNVTGIMSLNKLLDFEEKPTVFTVAIEVIDHGRPPLSLVVFVNVT 742

Query: 247  IRDVNDNAPRFYTSLFQESVSE-NVPIGYSIVR-VQAYDAD-EGVNAELTYTMTDKDYT- 302
            + +VNDN P F    +   +SE +  + ++IV  V A+D D +  N  L   +    YT 
Sbjct: 743  VDNVNDNYPSFGQDNYTFWISEGDFAVDHAIVGVVSAHDLDADSSNCPLCGKL---QYTL 799

Query: 303  GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG-GDPPRSATATXXXXXXXXXX 361
            GN   P  ID  +G +   G LDRE    Y   V A D   + P                
Sbjct: 800  GNSTGPFAIDKDTGVLRAVGSLDREGIKNYTFSVIAQDSIPNRPLVNVTMVTVNLLDVND 859

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419
                F    Y   ++ED  PG  V+ + A D D   +  + Y I  GNT   F +   N 
Sbjct: 860  NDPVFDRDVYTANVSEDASPGLTVLKIRAVDNDLASNANVSYSIVSGNTGAAFHV--DNV 917

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTAS 477
             G I +   L+ ++   Y LTV + D G   R  TA+V I + D N+ +PV  +   T  
Sbjct: 918  TGEIKLVSKLEREKITSYTLTVGSADGGAVPRRSTALVIIYVMDVNDNSPVCLHDTQTVR 977

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            + E+ P G  V+ V  TD D   N ++ Y+L+S+            F ++P TG ITT +
Sbjct: 978  LLENLPAGHFVVKVVTTDPDEVHNGRVEYNLTSD-----------AFRVDPFTGIITTTR 1026

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
             LDRE++  Y L VTAR+     +     V + V+D ND+ P F    Y  +  E   VG
Sbjct: 1027 ALDRESIPAYNLMVTARNSNSSDMEVNCSVHVIVMDTNDHTPSFTMARYYISTPETTPVG 1086

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
            +++ +V A D D G+N  + Y L     EE  F I+  +G++    +LDRE+ A + L+ 
Sbjct: 1087 STLFRVRAVDGDDGINAEVRYTL---MGEESLFRINYTTGIVTLVSSLDRENKAQYQLEV 1143

Query: 658  VAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
             A D G P   +++  + I++ D+ND+ P F        + E   +G     + A D DE
Sbjct: 1144 EARDRGIPESNANSTTILIRVGDVNDNRPTFTHAHYDGNVLEGQ-VGAVAAIVVALDKDE 1202

Query: 717  GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPP 773
              NA + YSI GG+  NSF++  + GS    + T++ LD E+   +Y L + A+    P 
Sbjct: 1203 EINADIVYSIIGGNTDNSFAINNKSGS----IYTLLHLDRET-TDRYILTVLASDRGEPA 1257

Query: 774  LWNDVRVEILVTDVNDNAP 792
            + +   V I V DVNDN P
Sbjct: 1258 MNSSTNVTIHVNDVNDNKP 1276



 Score =  303 bits (745), Expect = 3e-80
 Identities = 248/817 (30%), Positives = 398/817 (48%), Gaps = 77/817 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           +NVLD +D    F    Y AS+ E A+ G+ V+ + A D D   NA V Y I+  T    
Sbjct: 210 VNVLDADDLPVRFNNYSYSASIPENAAMGSVVMQVHAKDLDKSINAPVTYAIDKET---- 265

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           NP                +F I   +G +    SLDRE +A Y + + A    +   D  
Sbjct: 266 NP--------------LRMFNIANITGEITLNGSLDRETIAEYRLRILA--YCTIYQDHT 309

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
                + + + D NDN P F+  +Y  +V+E+ ++     + +++A D D G N++  Y 
Sbjct: 310 E----VLITVTDVNDNIPLFTLPSYNTTVNENAAI--GTYVIQVQAEDIDQGVNASFIYE 363

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS--RSNTTQLLINIR 248
           I       +F I   SG + +  TLD E+   Y + + A++  + +   SN T + + +R
Sbjct: 364 I--AYAGHEFVIGEHSGIIIVNGTLDREKKDLYSITVIARETETSAGFHSNVT-ITVMLR 420

Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
           D NDN+P F  +L+   + EN P G  +++V A D+D G NA ++Y +   D  G+    
Sbjct: 421 DENDNSPIFSRALYSSPIYENEPPGTFVIQVSANDSDIGSNAMVSYAVL-SDAEGHYQY- 478

Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG--DPPRSATATXXXXXXXXXXXXXXF 366
             I+ ++G + TS +LDRE    ++L VTA+DG      R +                 F
Sbjct: 479 FKINAKNGTITTSRRLDRENITTFRLRVTASDGAPLSTIRVSVVDVVVTVLDINDNSPEF 538

Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLIT 424
           +   Y   + E   PG  +  ++A D D+D    + Y IT GN  G F I +++  GL+ 
Sbjct: 539 VRPSYNFSVIETALPGAILGIISAVDRDKDLNGNIVYIITEGNVEGSFIIGARS--GLLQ 596

Query: 425 VAQPLDFKQERRYVLTVSATDSGGR--------SDTAMVQINITDANNYAPVFENAPYTA 476
           +   LD +   ++ L V+A+D GG         + T  V IN+ D+N+  PV +   YT 
Sbjct: 597 LNHTLDREVVSKHSLRVTASDRGGEFMADGSSLNTTINVTINVLDSNDNIPVCDKVYYTI 656

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
           S+ E+  +G +++ ++ TD D G NA + Y +        V+ H  +FV++  TG ++ N
Sbjct: 657 SIPENTSVGQSLIHLNCTDQDSGENAHLLYHM--------VSGH-SKFVVDNVTGIMSLN 707

Query: 537 KLLD-RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME--- 592
           KLLD  E  + + + +   D G P LS    V ++V +VNDN P F Q  YT  I E   
Sbjct: 708 KLLDFEEKPTVFTVAIEVIDHGRPPLSLVVFVNVTVDNVNDNYPSFGQDNYTFWISEGDF 767

Query: 593 ---DALVG-TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648
               A+VG  S   + A  ++  L G++ Y L       G F ID  +GV+R   +LDRE
Sbjct: 768 AVDHAIVGVVSAHDLDADSSNCPLCGKLQYTL---GNSTGPFAIDKDTGVLRAVGSLDRE 824

Query: 649 SVATHDLKAVAIDG-GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
            +  +    +A D     P  +  +V + + D+ND+ PVF+ D  T  +SE++  G T+ 
Sbjct: 825 GIKNYTFSVIAQDSIPNRPLVNVTMVTVNLLDVNDNDPVFDRDVYTANVSEDASPGLTVL 884

Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
           +IRA D D   NA V YSI  G+   +F ++   G  K  LV+ ++ +  +    Y L +
Sbjct: 885 KIRAVDNDLASNANVSYSIVSGNTGAAFHVDNVTGEIK--LVSKLEREKIT---SYTLTV 939

Query: 768 RAA---SPPLWNDVRVEILVTDVNDNAPV-MKDFQII 800
            +A   + P  +   V I V DVNDN+PV + D Q +
Sbjct: 940 GSADGGAVPRRSTALVIIYVMDVNDNSPVCLHDTQTV 976



 Score =  300 bits (736), Expect = 4e-79
 Identities = 251/868 (28%), Positives = 408/868 (47%), Gaps = 76/868 (8%)

Query: 36  ASSGTTVLTLKATDQDIGK-NAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDG 94
           ++SG +VLT+ ATD D  + N  V Y I  V+ +    ED              +F ID 
Sbjct: 122 STSGLSVLTMSATDMDAEEINQRVNYAI--VSGN----EDG-------------IFDIDF 162

Query: 95  RSGALLTRASLDREKVARYTVLVKA----TDQASPVSDRLSSTATIHVNIIDDNDNYPQF 150
             G +     LD E++ +Y + + A    T+      + LS+   + VN++D +D   +F
Sbjct: 163 NKGVIRLARELDFEQMTQYKLNISASNPLTNDTVIPKNGLSNWTMVTVNVLDADDLPVRF 222

Query: 151 SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ-FSIDSLSGDV 209
           +  +Y+ S+ E+ ++    V+ ++ A D D   N+ + YAI      ++ F+I +++G++
Sbjct: 223 NNYSYSASIPENAAM--GSVVMQVHAKDLDKSINAPVTYAIDKETNPLRMFNIANITGEI 280

Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269
           +L  +LD E +  YRL I A         + T++LI + DVNDN P F    +  +V+EN
Sbjct: 281 TLNGSLDRETIAEYRLRILAY---CTIYQDHTEVLITVTDVNDNIPLFTLPSYNTTVNEN 337

Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329
             IG  +++VQA D D+GVNA   Y +    Y G+      I   SG +  +G LDRE +
Sbjct: 338 AAIGTYVIQVQAEDIDQGVNASFIYEIA---YAGH---EFVIGEHSGIIIVNGTLDREKK 391

Query: 330 AKYQLLVTATDGGDPPR-SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388
             Y + V A +        +  T              F    Y   + E+EPPGT V+ +
Sbjct: 392 DLYSITVIARETETSAGFHSNVTITVMLRDENDNSPIFSRALYSSPIYENEPPGTFVIQV 451

Query: 389 TATDAD--EDNRLHYEITGGNTRGRFSITSQNGR-GLITVAQPLDFKQERRYVLTVSATD 445
           +A D+D   +  + Y +   +  G +     N + G IT ++ LD +    + L V+A+D
Sbjct: 452 SANDSDIGSNAMVSYAVLS-DAEGHYQYFKINAKNGTITTSRRLDRENITTFRLRVTASD 510

Query: 446 SGGRSDTAM----VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501
               S   +    V + + D N+ +P F    Y  SV E A  G  + ++SA D D  +N
Sbjct: 511 GAPLSTIRVSVVDVVVTVLDINDNSPEFVRPSYNFSVIETALPGAILGIISAVDRDKDLN 570

Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP-- 559
             I Y ++         + +  F+I  ++G +  N  LDRE +S + L VTA D G    
Sbjct: 571 GNIVYIITE-------GNVEGSFIIGARSGLLQLNHTLDREVVSKHSLRVTASDRGGEFM 623

Query: 560 ----SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615
               SL+ T +V I+V+D NDN PV  +  YT +I E+  VG S+  +  TD D G N  
Sbjct: 624 ADGSSLNTTINVTINVLDSNDNIPVCDKVYYTISIPENTSVGQSLIHLNCTDQDSGENAH 683

Query: 616 IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV-AIDGGTPPQSSTVIVH 674
           + Y +         FV+D  +G++  NK LD E   T    A+  ID G PP S  V V+
Sbjct: 684 LLYHMVSG---HSKFVVDNVTGIMSLNKLLDFEEKPTVFTVAIEVIDHGRPPLSLVVFVN 740

Query: 675 IKIEDINDSPPVFESDCLTFYISEN--SPIGTTIGEIRAHDPD-EGPNAVVHYSIKG--G 729
           + ++++ND+ P F  D  TF+ISE   +     +G + AHD D +  N  +   ++   G
Sbjct: 741 VTVDNVNDNYPSFGQDNYTFWISEGDFAVDHAIVGVVSAHDLDADSSNCPLCGKLQYTLG 800

Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIRAASP--PLWNDVRVEILVTD 786
           + +  F+++     D   L  +  LD E  +   + ++ + + P  PL N   V + + D
Sbjct: 801 NSTGPFAID----KDTGVLRAVGSLDREGIKNYTFSVIAQDSIPNRPLVNVTMVTVNLLD 856

Query: 787 VNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNNANLILLNE 844
           VNDN PV        N  +D  P     ++ A D D+     + Y I+SGN      ++ 
Sbjct: 857 VNDNDPVFDRDVYTANVSEDASPGLTVLKIRAVDNDLASNANVSYSIVSGNTGAAFHVDN 916

Query: 845 TTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            TG + L  +L        T+ V   DG
Sbjct: 917 VTGEIKLVSKLEREKITSYTLTVGSADG 944



 Score =  283 bits (693), Expect = 6e-74
 Identities = 217/700 (31%), Positives = 334/700 (47%), Gaps = 61/700 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V+D ND+SPV         + E   +G  V+ +  TD D   N  VEY +        
Sbjct: 957  IYVMDVNDNSPVCLHDTQTVRLLENLPAGHFVVKVVTTDPDEVHNGRVEYNL-------- 1008

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                             D FR+D  +G + T  +LDRE +  Y ++V A +  S  SD +
Sbjct: 1009 ---------------TSDAFRVDPFTGIITTTRALDRESIPAYNLMVTARNSNS--SD-M 1050

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
                ++HV ++D ND+ P F+   Y +S  E   V     + +++A D D G N+ +RY 
Sbjct: 1051 EVNCSVHVIVMDTNDHTPSFTMARYYISTPETTPV--GSTLFRVRAVDGDDGINAEVRYT 1108

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP-SRSNTTQLLINIRD 249
            ++G   +  F I+  +G V+LV +LD E    Y+L + A+D G P S +N+T +LI + D
Sbjct: 1109 LMG--EESLFRINYTTGIVTLVSSLDRENKAQYQLEVEARDRGIPESNANSTTILIRVGD 1166

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            VNDN P F  + +  +V E   +G     V A D DE +NA++ Y++      GN D   
Sbjct: 1167 VNDNRPTFTHAHYDGNVLEG-QVGAVAAIVVALDKDEEINADIVYSIIG----GNTDNSF 1221

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             I+ +SG +YT   LDRET  +Y L V A+D G+P  +++                    
Sbjct: 1222 AINNKSGSIYTLLHLDRETTDRYILTVLASDRGEPAMNSSTNVTIHVNDVNDNKPNITNN 1281

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITG-GNTRGRFSITSQNGRGLITVAQP 428
               V   E+ PPG+ V  L+A+D DE +      +G     G+FSI   NG   I V   
Sbjct: 1282 PGVVVTRENTPPGSLVYILSASDLDEGSNARVAFSGYAVPDGKFSI-KPNGE--IMVRDS 1338

Query: 429  LDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
            LD + + R+V    ATDSG     S      I I D N+  PVF+   Y+ ++ E+ P  
Sbjct: 1339 LDREAQNRFVFYAMATDSGQPPFNSSMVSFDILIADENDNNPVFDPVHYSVNISENGPSE 1398

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
              ++ V+A++ D G   ++ + +SS             F I+  TG I+T K LDRE +S
Sbjct: 1399 EVIVQVNASERDEG---KLLFKISS-------GDPGGYFTIHNVTGVISTRKPLDREMVS 1448

Query: 546  GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
             + LT+TA D G PS      V I V D ND  PV +Q     ++ E+A +G++V+ + A
Sbjct: 1449 RFDLTITAEDEGRPSRMALGYVTIFVNDENDFAPVIEQCEQLVSVSENAHIGSAVASINA 1508

Query: 606  TDADVGLNGRIHYELDPKDREEGSFVIDPASG-----VIRTNKALDRESVATHDLKAVAI 660
             D D   N +I Y +        +  +  +SG     +I T   LDRE    +++   A 
Sbjct: 1509 VDKDDPSNTKITYSVGNSAFNITTQRLPFSSGSRYRGIIITAGLLDRERQDNYNITVTAS 1568

Query: 661  DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700
            DG      +T  + ++I D+ND+ PVF    +   + E S
Sbjct: 1569 DGN---HIATCNIIVRITDVNDNSPVFNQTTMNISLHEVS 1605



 Score =  279 bits (684), Expect = 8e-73
 Identities = 226/744 (30%), Positives = 348/744 (46%), Gaps = 53/744 (7%)

Query: 161 EDISVTDNPVIAKIKATDADVGA-NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQ 219
           E    T    +  + ATD D    N  + YAI+ GN    F ID   G + L + LD+EQ
Sbjct: 118 ETCKSTSGLSVLTMSATDMDAEEINQRVNYAIVSGNEDGIFDIDFNKGVIRLARELDFEQ 177

Query: 220 VRSYRLVIRAQ-----DGGSPSR--SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI 272
           +  Y+L I A      D   P    SN T + +N+ D +D   RF    +  S+ EN  +
Sbjct: 178 MTQYKLNISASNPLTNDTVIPKNGLSNWTMVTVNVLDADDLPVRFNNYSYSASIPENAAM 237

Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332
           G  +++V A D D+ +NA +TY + DK+ T  + +   I   +G +  +G LDRET A+Y
Sbjct: 238 GSVVMQVHAKDLDKSINAPVTYAI-DKE-TNPLRM-FNIANITGEITLNGSLDRETIAEY 294

Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392
           +L + A       +  T                 +P  Y   + E+   GT V+ + A D
Sbjct: 295 RLRILAYC--TIYQDHTEVLITVTDVNDNIPLFTLPS-YNTTVNENAAIGTYVIQVQAED 351

Query: 393 ADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD---SGGR 449
            D+     +          F I   +G  +I V   LD +++  Y +TV A +   S G 
Sbjct: 352 IDQGVNASFIYEIAYAGHEFVIGEHSG--IIIVNGTLDREKKDLYSITVIARETETSAGF 409

Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509
                + + + D N+ +P+F  A Y++ ++E+ P GT V+ VSA DSD+G NA ++Y++ 
Sbjct: 410 HSNVTITVMLRDENDNSPIFSRALYSSPIYENEPPGTFVIQVSANDSDIGSNAMVSYAVL 469

Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL--SDTTDV 567
           S+        H Q F IN + G ITT++ LDRE ++ + L VTA DG   S       DV
Sbjct: 470 SDAEG-----HYQYFKINAKNGTITTSRRLDRENITTFRLRVTASDGAPLSTIRVSVVDV 524

Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627
            ++V+D+NDN P F +  Y  +++E AL G  +  + A D D  LNG I Y +  +   E
Sbjct: 525 VVTVLDINDNSPEFVRPSYNFSVIETALPGAILGIISAVDRDKDLNGNIVY-IITEGNVE 583

Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG------TPPQSSTVIVHIKIEDIN 681
           GSF+I   SG+++ N  LDRE V+ H L+  A D G          ++T+ V I + D N
Sbjct: 584 GSFIIGARSGLLQLNHTLDREVVSKHSLRVTASDRGGEFMADGSSLNTTINVTINVLDSN 643

Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741
           D+ PV +    T  I EN+ +G ++  +   D D G NA + Y +  G   + F ++   
Sbjct: 644 DNIPVCDKVYYTISIPENTSVGQSLIHLNCTDQDSGENAHLLYHMVSG--HSKFVVDNVT 701

Query: 742 GSDKAELVTMVDLDYESPRKKYEL---VIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQ 798
           G      +    LD+E     + +   VI    PPL   V V + V +VNDN P      
Sbjct: 702 GIMSLNKL----LDFEEKPTVFTVAIEVIDHGRPPLSLVVFVNVTVDNVNDNYPSFGQDN 757

Query: 799 IIFNNYKDCFPV--GPFGRVPAYDAD-------VTDKLQYRILSGNNANLILLNETTGSM 849
             F   +  F V     G V A+D D       +  KLQY +  GN+     +++ TG +
Sbjct: 758 YTFWISEGDFAVDHAIVGVVSAHDLDADSSNCPLCGKLQYTL--GNSTGPFAIDKDTGVL 815

Query: 850 TLSPQLNTNVPKLATMEVSVTDGV 873
                L+    K  T  V   D +
Sbjct: 816 RAVGSLDREGIKNYTFSVIAQDSI 839



 Score =  274 bits (671), Expect = 3e-71
 Identities = 200/599 (33%), Positives = 295/599 (49%), Gaps = 46/599 (7%)

Query: 1    MSVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEY 60
            M V   +H  + V+D NDH+P F M +Y  S  E    G+T+  ++A D D G NAEV Y
Sbjct: 1050 MEVNCSVH--VIVMDTNDHTPSFTMARYYISTPETTPVGSTLFRVRAVDGDDGINAEVRY 1107

Query: 61   TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT 120
            T+                        + +FRI+  +G +   +SLDRE  A+Y + V+A 
Sbjct: 1108 TL---------------------MGEESLFRINYTTGIVTLVSSLDRENKAQYQLEVEAR 1146

Query: 121  DQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD 180
            D+  P S+  S+T  I V   D NDN P F+   Y  +V E        V A + A D D
Sbjct: 1147 DRGIPESNANSTTILIRVG--DVNDNRPTFTHAHYDGNVLEG---QVGAVAAIVVALDKD 1201

Query: 181  VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240
               N+ I Y+IIGGNT   F+I++ SG +  +  LD E    Y L + A D G P+ +++
Sbjct: 1202 EEINADIVYSIIGGNTDNSFAINNKSGSIYTLLHLDRETTDRYILTVLASDRGEPAMNSS 1261

Query: 241  TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
            T + I++ DVNDN P    +       EN P G  +  + A D DEG NA + ++     
Sbjct: 1262 TNVTIHVNDVNDNKPNITNNPGVVVTRENTPPGSLVYILSASDLDEGSNARVAFS----G 1317

Query: 301  YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP-RSATATXXXXXXXX 359
            Y    D   +I P +G +     LDRE Q ++     ATD G PP  S+  +        
Sbjct: 1318 Y-AVPDGKFSIKP-NGEIMVRDSLDREAQNRFVFYAMATDSGQPPFNSSMVSFDILIADE 1375

Query: 360  XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG 419
                  F P  Y V ++E+ P    +V + A++ DE  +L ++I+ G+  G F+I   N 
Sbjct: 1376 NDNNPVFDPVHYSVNISENGPSEEVIVQVNASERDE-GKLLFKISSGDPGGYFTI--HNV 1432

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTAS 477
             G+I+  +PLD +   R+ LT++A D G  S  A+  V I + D N++APV E      S
Sbjct: 1433 TGVISTRKPLDREMVSRFDLTITAEDEGRPSRMALGYVTIFVNDENDFAPVIEQCEQLVS 1492

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ-TGAITTN 536
            V E+A IG+ V  ++A D D   N +ITYS+ +   N  +      F    +  G I T 
Sbjct: 1493 VSENAHIGSAVASINAVDKDDPSNTKITYSVGNSAFN--ITTQRLPFSSGSRYRGIIITA 1550

Query: 537  KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
             LLDRE    Y +TVTA DG   +   T ++ + + DVNDN PVF Q     ++ E +L
Sbjct: 1551 GLLDRERQDNYNITVTASDGNHIA---TCNIIVRITDVNDNSPVFNQTTMNISLHEVSL 1606



 Score =  217 bits (529), Expect = 5e-54
 Identities = 164/519 (31%), Positives = 255/519 (49%), Gaps = 41/519 (7%)

Query: 382 GTPVVTLTATDADEDN---RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYV 438
           G  V+T++ATD D +    R++Y I  GN  G F I     +G+I +A+ LDF+Q  +Y 
Sbjct: 125 GLSVLTMSATDMDAEEINQRVNYAIVSGNEDGIFDIDFN--KGVIRLARELDFEQMTQYK 182

Query: 439 LTVSATD---------SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
           L +SA++           G S+  MV +N+ DA++    F N  Y+AS+ E+A +G+ V+
Sbjct: 183 LNISASNPLTNDTVIPKNGLSNWTMVTVNVLDADDLPVRFNNYSYSASIPENAAMGSVVM 242

Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
            V A D D  INA +TY++  E +N       + F I   TG IT N  LDRET++ Y L
Sbjct: 243 QVHAKDLDKSINAPVTYAIDKE-TNPL-----RMFNIANITGEITLNGSLDRETIAEYRL 296

Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
            + A         D T+V I+V DVNDN P+F    Y   + E+A +GT V QV A D D
Sbjct: 297 RILAY---CTIYQDHTEVLITVTDVNDNIPLFTLPSYNTTVNENAAIGTYVIQVQAEDID 353

Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ-S 668
            G+N    YE+     E   FVI   SG+I  N  LDRE    + +  +A +  T     
Sbjct: 354 QGVNASFIYEIAYAGHE---FVIGEHSGIIIVNGTLDREKKDLYSITVIARETETSAGFH 410

Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
           S V + + + D ND+ P+F     +  I EN P GT + ++ A+D D G NA+V Y++  
Sbjct: 411 SNVTITVMLRDENDNSPIFSRALYSSPIYENEPPGTFVIQVSANDSDIGSNAMVSYAVLS 470

Query: 729 GDDSNS--FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEIL--- 783
             + +   F +  + G+    + T   LD E+    + L + A+     + +RV ++   
Sbjct: 471 DAEGHYQYFKINAKNGT----ITTSRRLDRENITT-FRLRVTASDGAPLSTIRVSVVDVV 525

Query: 784 --VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANL 839
             V D+NDN+P        F+  +   P    G + A D D  +   + Y I  GN    
Sbjct: 526 VTVLDINDNSPEFVRPSYNFSVIETALPGAILGIISAVDRDKDLNGNIVYIITEGNVEGS 585

Query: 840 ILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKA 878
            ++   +G + L+  L+  V    ++ V+ +D   E  A
Sbjct: 586 FIIGARSGLLQLNHTLDREVVSKHSLRVTASDRGGEFMA 624



 Score =  131 bits (317), Expect = 2e-28
 Identities = 135/482 (28%), Positives = 232/482 (48%), Gaps = 47/482 (9%)

Query: 485 GTTVLVVSATDSDVG-INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
           G +VL +SATD D   IN ++ Y++ S   NE     D  F I+   G I   + LD E 
Sbjct: 125 GLSVLTMSATDMDAEEINQRVNYAIVS--GNE-----DGIFDIDFNKGVIRLARELDFEQ 177

Query: 544 MSGYLLTVTA-----RDGGVPS--LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
           M+ Y L ++A      D  +P   LS+ T V ++V+D +D    F    Y+A+I E+A +
Sbjct: 178 MTQYKLNISASNPLTNDTVIPKNGLSNWTMVTVNVLDADDLPVRFNNYSYSASIPENAAM 237

Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
           G+ V QV A D D  +N  + Y +D +      F I   +G I  N +LDRE++A + L+
Sbjct: 238 GSVVMQVHAKDLDKSINAPVTYAIDKETNPLRMFNIANITGEITLNGSLDRETIAEYRLR 297

Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
            +A    T  Q  T ++ I + D+ND+ P+F        ++EN+ IGT + +++A D D+
Sbjct: 298 ILAY--CTIYQDHTEVL-ITVTDVNDNIPLFTLPSYNTTVNENAAIGTYVIQVQAEDIDQ 354

Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA----ASP 772
           G NA   Y I      + F +    G     ++    LD E  +  Y + + A     S 
Sbjct: 355 GVNASFIYEIAYA--GHEFVI----GEHSGIIIVNGTLDREK-KDLYSITVIARETETSA 407

Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVTDK--LQY 829
              ++V + +++ D NDN+P+          Y++  P G F  +V A D+D+     + Y
Sbjct: 408 GFHSNVTITVMLRDENDNSPIFSRALYSSPIYEN-EPPGTFVIQVSANDSDIGSNAMVSY 466

Query: 830 RILSG--NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887
            +LS    +     +N   G++T S +L+        + V+ +DG     A +  ++R+ 
Sbjct: 467 AVLSDAEGHYQYFKINAKNGTITTSRRLDRENITTFRLRVTASDG-----APLS-TIRVS 520

Query: 888 TEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNIL 947
             ++++  + +  ND + E F+ P   F +  +   +P     I I +V  D D+ GNI+
Sbjct: 521 VVDVVVTVLDI--NDNSPE-FVRPSYNFSV--IETALPGAILGI-ISAVDRDKDLNGNIV 574

Query: 948 NV 949
            +
Sbjct: 575 YI 576


>UniRef50_UPI00006610B3 Cluster: Homolog of Brachydanio rerio
           "Cadherin-related neuronal receptor variable 9.; n=1;
           Takifugu rubripes|Rep: Homolog of Brachydanio rerio
           "Cadherin-related neuronal receptor variable 9. -
           Takifugu rubripes
          Length = 1254

 Score =  327 bits (803), Expect = 3e-87
 Identities = 262/908 (28%), Positives = 413/908 (45%), Gaps = 62/908 (6%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +INV+D ND+ P+F    Y+  V E A+ G T+LTL ATD D G N E+ Y+        
Sbjct: 9   RINVIDVNDNYPLFSKSLYKVQVVENANVGATILTLSATDLDDGVNGELVYSF--AERGR 66

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            NPED               F ++  +G +  + ++D E+   Y + V+A D+ +P    
Sbjct: 67  FNPEDK--------------FALNAHNGEITLKGNIDYEENPAYEIRVQARDKGAPPR-- 110

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            ++ + + V +ID NDN P+ S  +    V ED  +     +A +   D D G N     
Sbjct: 111 -TAHSKVLVEVIDVNDNAPEISVSSLMSPVKEDAGL--GTAVAMVTINDRDGGKNGLTNC 167

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            I G    M  S       + +   LD E    Y + I A+D G+PS + TT + + I D
Sbjct: 168 RITGSVPFMLKSNYKNYYSLVVDGPLDRETASQYNVTITAEDEGTPSLTGTTIINVQISD 227

Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
           VNDN PRF  SL    + EN P+G ++ R+   D+D   NA+ TY + +      V   I
Sbjct: 228 VNDNPPRFPDSLLNVYLKENSPVGSTVHRLTTLDSDLNENAKATYHLLNNSPKSGVAAMI 287

Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            I+  +G + +    + E    +Q  V ATD G PP S+  T               +  
Sbjct: 288 NINSETGDIISLQSFNYEELKTFQFKVQATDSGVPPLSSNVTVNVFILDENDNSPTILAP 347

Query: 370 QYEVELAEDE------PPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRG 421
             E      E        G  V  + A DAD   +  L Y ++       F + +  G  
Sbjct: 348 YSEHGSVNSESIPYSAEAGYFVAKIRAVDADSGYNALLSYHLSEPKGNNLFRMGTSTGE- 406

Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV---FENAPYTASV 478
            I   + +     + + L V  +D+G  S +A V I +    + A +   F + P     
Sbjct: 407 -IRTKRRMSDNDLKTHPLVVLVSDNGDPSLSATVSIEVVVVESAADIQTQFRHVPMKEES 465

Query: 479 FEDAPIGTTVLVVSATD---SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
           F D  +   + +VS +     + G N+   Y +S   +NE  +  D     +  +  +  
Sbjct: 466 FSDLNLYLLIAIVSVSAIFLLNTGSNSVKAYKIS---ANEHFS-VDVSSGADGTSAELVL 521

Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
            K LDRE  +   LT+TA DGG P+ S T  + ++V+DVNDN PVF Q LY   + E   
Sbjct: 522 EKALDREKQALIKLTLTAVDGGKPARSGTLQILVNVIDVNDNTPVFSQSLYKVRVSEGVP 581

Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDR-EEGSFVIDPASGVIRTNKALDRESVATHD 654
           VGT + ++ A D D G NG + Y L  +       F +DP SG I    +LD E    ++
Sbjct: 582 VGTQILKLNANDLDEGSNGDLRYSLMKRGNVNSEKFSVDPESGEIVVKASLDYEESGAYE 641

Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
           L+  A D G  P+S    V +++ D+ND+ P      L   I E++ +GT +  +   D 
Sbjct: 642 LRVQATDQGASPRSGYSKVLVEVLDVNDNAPEISVTSLMSPIKESAGLGTVVALVSVTDK 701

Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---AS 771
           D G N  +   I+   DS+ F+L++   S  + +V  + LD E+   +Y++ I A    +
Sbjct: 702 DGGQNGHLSCKIR---DSSPFALKSNYKSYYSLVVDGL-LDRET-ISQYDVTIVATDEGT 756

Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY-KDCFPVGP-FGRVPAYDADVTD--KL 827
           PPL +   + + ++DVNDNAP   D  +  N Y K+   VG    R  A DADV D  KL
Sbjct: 757 PPLSSTAVISVQISDVNDNAPRFMDENL--NIYIKENSRVGDIITRASAQDADVNDNAKL 814

Query: 828 QYRILSGNNANLIL-----LNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQ 881
            Y +L  +  ++++     +N  TG +      N    K    +V  TD GV  + + + 
Sbjct: 815 TYSLLDSHQKDVLISTVVNINSATGDIISLQSFNYEELKTFQFKVQATDSGVPPLSSNVT 874

Query: 882 LSVRLITE 889
           ++V ++ E
Sbjct: 875 VNVFILDE 882



 Score =  293 bits (718), Expect = 6e-77
 Identities = 226/828 (27%), Positives = 393/828 (47%), Gaps = 60/828 (7%)

Query: 98  ALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTV 157
           +L+    LDRE  ++Y V + A D+ +P    L+ T  I+V I D NDN P+F +    V
Sbjct: 186 SLVVDGPLDRETASQYNVTITAEDEGTP---SLTGTTIINVQISDVNDNPPRFPDSLLNV 242

Query: 158 SVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQM----QFSIDSLSGDVSLVK 213
            + E+  V     + ++   D+D+  N+   Y ++  + +       +I+S +GD+  ++
Sbjct: 243 YLKENSPV--GSTVHRLTTLDSDLNENAKATYHLLNNSPKSGVAAMININSETGDIISLQ 300

Query: 214 TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF------YTSLFQESVS 267
           + +YE++++++  ++A D G P  S+   + + I D NDN+P        + S+  ES+ 
Sbjct: 301 SFNYEELKTFQFKVQATDSGVPPLSSNVTVNVFILDENDNSPTILAPYSEHGSVNSESIP 360

Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
            +   GY + +++A DAD G NA L+Y +++    GN +L   +   +G + T  ++   
Sbjct: 361 YSAEAGYFVAKIRAVDADSGYNALLSYHLSEPK--GN-NL-FRMGTSTGEIRTKRRMSDN 416

Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX---FMPGQYEVELAEDEPPGTP 384
               + L+V  +D GDP  SAT +                  +P + E     +      
Sbjct: 417 DLKTHPLVVLVSDNGDPSLSATVSIEVVVVESAADIQTQFRHVPMKEESFSDLNLYLLIA 476

Query: 385 VVTLTAT---DADEDNRLHYEITGGNTRGRFSITSQNGR----GLITVAQPLDFKQERRY 437
           +V+++A    +   ++   Y+I+       FS+   +G       + + + LD +++   
Sbjct: 477 IVSVSAIFLLNTGSNSVKAYKISANE---HFSVDVSSGADGTSAELVLEKALDREKQALI 533

Query: 438 VLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495
            LT++A D G   RS T  + +N+ D N+  PVF  + Y   V E  P+GT +L ++A D
Sbjct: 534 KLTLTAVDGGKPARSGTLQILVNVIDVNDNTPVFSQSLYKVRVSEGVPVGTQILKLNAND 593

Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555
            D G N  + YSL     N     + ++F ++P++G I     LD E    Y L V A D
Sbjct: 594 LDEGSNGDLRYSLMKR-GNV----NSEKFSVDPESGEIVVKASLDYEESGAYELRVQATD 648

Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615
            G    S  + V + V+DVNDN P        + I E A +GT V+ V  TD D G NG 
Sbjct: 649 QGASPRSGYSKVLVEVLDVNDNAPEISVTSLMSPIKESAGLGTVVALVSVTDKDGGQNGH 708

Query: 616 IHYELDPKDREEGSFVIDP---ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672
               L  K R+   F +     +   +  +  LDRE+++ +D+  VA D GTPP SST +
Sbjct: 709 ----LSCKIRDSSPFALKSNYKSYYSLVVDGLLDRETISQYDVTIVATDEGTPPLSSTAV 764

Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732
           + ++I D+ND+ P F  + L  YI ENS +G  I    A D D   NA + YS+      
Sbjct: 765 ISVQISDVNDNAPRFMDENLNIYIKENSRVGDIITRASAQDADVNDNAKLTYSLLDSHQK 824

Query: 733 NSF-SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVN 788
           +   S      S   +++++   +YE   K ++  ++A     PPL ++V V + + D N
Sbjct: 825 DVLISTVVNINSATGDIISLQSFNYEE-LKTFQFKVQATDSGVPPLSSNVTVNVFILDEN 883

Query: 789 DNAP-VMKDFQIIFNNYKDCFP----VGPF-GRVPAYDAD--VTDKLQYRILSGNNANLI 840
           DN+P ++  +    +   +  P     G F  ++ A DAD      L Y +      NL 
Sbjct: 884 DNSPTILAPYSEHGSVNSESIPYSAEAGYFVAKIRAVDADSGYNALLSYHLSEPKGNNLF 943

Query: 841 LLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLI 887
            +  +TG +    +++ N  K   + V V+D G   + A + + V ++
Sbjct: 944 RMGTSTGEIRTKRRMSDNDLKTHPLVVLVSDNGDPSLSATVSIEVVVV 991



 Score =  280 bits (686), Expect = 5e-73
 Identities = 220/725 (30%), Positives = 336/725 (46%), Gaps = 47/725 (6%)

Query: 93   DGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSE 152
            DG S  L+   +LDREK A   + + A D   P     S T  I VN+ID NDN P FS+
Sbjct: 513  DGTSAELVLEKALDREKQALIKLTLTAVDGGKPAR---SGTLQILVNVIDVNDNTPVFSQ 569

Query: 153  KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG-GNTQMQ-FSIDSLSGDVS 210
              Y V V E + V     I K+ A D D G+N  +RY+++  GN   + FS+D  SG++ 
Sbjct: 570  SLYKVRVSEGVPVGTQ--ILKLNANDLDEGSNGDLRYSLMKRGNVNSEKFSVDPESGEIV 627

Query: 211  LVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENV 270
            +  +LDYE+  +Y L ++A D G+  RS  +++L+ + DVNDNAP    +     + E+ 
Sbjct: 628  VKASLDYEESGAYELRVQATDQGASPRSGYSKVLVEVLDVNDNAPEISVTSLMSPIKESA 687

Query: 271  PIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW-VYTSGQLDRETQ 329
             +G  +  V   D D G N  L+  + D          +  + +S + +   G LDRET 
Sbjct: 688  GLGTVVALVSVTDKDGGQNGHLSCKIRDSS-----PFALKSNYKSYYSLVVDGLLDRETI 742

Query: 330  AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389
            ++Y + + ATD G PP S+TA               FM     + + E+   G  +   +
Sbjct: 743  SQYDVTIVATDEGTPPLSSTAVISVQISDVNDNAPRFMDENLNIYIKENSRVGDIITRAS 802

Query: 390  ATDAD-EDN-RLHYEITGGNTRGRFSITSQN---GRGLITVAQPLDFKQERRYVLTVSAT 444
            A DAD  DN +L Y +   + +     T  N     G I   Q  ++++ + +   V AT
Sbjct: 803  AQDADVNDNAKLTYSLLDSHQKDVLISTVVNINSATGDIISLQSFNYEELKTFQFKVQAT 862

Query: 445  DSG--GRSDTAMVQINITDANNYAPVFENAPYTA-------SVFEDAPIGTTVLVVSATD 495
            DSG    S    V + I D N+ +P    APY+        S+   A  G  V  + A D
Sbjct: 863  DSGVPPLSSNVTVNVFILDENDNSPTIL-APYSEHGSVNSESIPYSAEAGYFVAKIRAVD 921

Query: 496  SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555
            +D G NA ++Y LS    N         F +   TG I T + +    +  + L V   D
Sbjct: 922  ADSGYNALLSYHLSEPKGNNL-------FRMGTSTGEIRTKRRMSDNDLKTHPLVVLVSD 974

Query: 556  GGVPSLSDTTDVEISVVD-VNDNEPVFKQQLYTANIMEDALVGTSVSQV-GATDADVGLN 613
             G PSLS T  +E+ VV+   D +  F+          D  +   ++ V  ATD D G N
Sbjct: 975  NGDPSLSATVSIEVVVVESAADIQTQFRHVPMKEESFSDLNLYLLIAIVLNATDLDEGQN 1034

Query: 614  GRIHYELDPKDREEGSFVIDPAS--GVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671
            G+I Y    +   + S + D  S  G I+    LD E    ++++  A D GT P+S+  
Sbjct: 1035 GKIKYSFIKRGNSDPSNIFDLNSDTGEIKVKGELDYEETPAYEVRVQANDQGTTPRSAHA 1094

Query: 672  IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD 731
             + I+I D ND+ P      L   + E++ +GT +  I  +D D G N V    + G   
Sbjct: 1095 KLLIEIIDENDNAPEISVTSLMTPLKEDAELGTIVALITVNDKDGGKNGVAVCKVVG--- 1151

Query: 732  SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVN 788
            S  F L++    ++  LV    LD E+    Y + ++A     PPL     + + ++DVN
Sbjct: 1152 SVPFKLKSNY-KNEYSLVVDGALDREN-TSVYNVTVQATDEGDPPLSTIKVITVHISDVN 1209

Query: 789  DNAPV 793
            DNAPV
Sbjct: 1210 DNAPV 1214



 Score =  272 bits (667), Expect = 9e-71
 Identities = 211/692 (30%), Positives = 328/692 (47%), Gaps = 52/692 (7%)

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           S    I +N+ID NDNYP FS+  Y V V E+ +V     I  + ATD D G N  + Y+
Sbjct: 3   SGNLQIRINVIDVNDNYPLFSKSLYKVQVVENANV--GATILTLSATDLDDGVNGELVYS 60

Query: 191 IIGG---NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
                  N + +F++++ +G+++L   +DYE+  +Y + ++A+D G+P R+  +++L+ +
Sbjct: 61  FAERGRFNPEDKFALNAHNGEITLKGNIDYEENPAYEIRVQARDKGAPPRTAHSKVLVEV 120

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            DVNDNAP    S     V E+  +G ++  V   D D G N      +T+   TG+V  
Sbjct: 121 IDVNDNAPEISVSSLMSPVKEDAGLGTAVAMVTINDRDGGKNG-----LTNCRITGSVPF 175

Query: 308 PITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
            +  + ++ + +   G LDRET ++Y + +TA D G P  + T                F
Sbjct: 176 MLKSNYKNYYSLVVDGPLDRETASQYNVTITAEDEGTPSLTGTTIINVQISDVNDNPPRF 235

Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFS--ITSQNGRGL 422
                 V L E+ P G+ V  LT  D+D  E+ +  Y +   + +   +  I   +  G 
Sbjct: 236 PDSLLNVYLKENSPVGSTVHRLTTLDSDLNENAKATYHLLNNSPKSGVAAMININSETGD 295

Query: 423 ITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPY------ 474
           I   Q  ++++ + +   V ATDSG    S    V + I D N+ +P    APY      
Sbjct: 296 IISLQSFNYEELKTFQFKVQATDSGVPPLSSNVTVNVFILDENDNSPTI-LAPYSEHGSV 354

Query: 475 -TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
            + S+   A  G  V  + A D+D G NA ++Y LS    N         F +   TG I
Sbjct: 355 NSESIPYSAEAGYFVAKIRAVDADSGYNALLSYHLSEPKGNNL-------FRMGTSTGEI 407

Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD-VNDNEPVFKQQLYTANIME 592
            T + +    +  + L V   D G PSLS T  +E+ VV+   D +  F+          
Sbjct: 408 RTKRRMSDNDLKTHPLVVLVSDNGDPSLSATVSIEVVVVESAADIQTQFRHVPMKEESFS 467

Query: 593 DA---LVGTSVSQVGATDADVGLNGRIHYELDPKDR--EEGSFVIDPASGVIRTNKALDR 647
           D    L+   VS       + G N    Y++   +    + S   D  S  +   KALDR
Sbjct: 468 DLNLYLLIAIVSVSAIFLLNTGSNSVKAYKISANEHFSVDVSSGADGTSAELVLEKALDR 527

Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
           E  A   L   A+DGG P +S T+ + + + D+ND+ PVF        +SE  P+GT I 
Sbjct: 528 EKQALIKLTLTAVDGGKPARSGTLQILVNVIDVNDNTPVFSQSLYKVRVSEGVPVGTQIL 587

Query: 708 EIRAHDPDEGPNAVVHYSI--KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765
           ++ A+D DEG N  + YS+  +G  +S  FS++   G    E+V    LDYE     YEL
Sbjct: 588 KLNANDLDEGSNGDLRYSLMKRGNVNSEKFSVDPESG----EIVVKASLDYEE-SGAYEL 642

Query: 766 VIRA----ASPPL-WNDVRVEILVTDVNDNAP 792
            ++A    ASP   ++ V VE+L  DVNDNAP
Sbjct: 643 RVQATDQGASPRSGYSKVLVEVL--DVNDNAP 672



 Score =  269 bits (659), Expect = 9e-70
 Identities = 218/740 (29%), Positives = 326/740 (44%), Gaps = 64/740 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +NV+D ND++PVF    Y+  V EG   GT +L L A D D G N ++ Y+  L+    +
Sbjct: 555  VNVIDVNDNTPVFSQSLYKVRVSEGVPVGTQILKLNANDLDEGSNGDLRYS--LMKRGNV 612

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N E                F +D  SG ++ +ASLD E+   Y + V+ATDQ +  S R 
Sbjct: 613  NSEK---------------FSVDPESGEIVVKASLDYEESGAYELRVQATDQGA--SPR- 654

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S  + + V ++D NDN P+ S  +    + E   +    V+A +  TD D G N  +   
Sbjct: 655  SGYSKVLVEVLDVNDNAPEISVTSLMSPIKESAGL--GTVVALVSVTDKDGGQNGHLSCK 712

Query: 191  IIGGNTQMQFSIDS-LSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            I        F++ S      SLV    LD E +  Y + I A D G+P  S+T  + + I
Sbjct: 713  I---RDSSPFALKSNYKSYYSLVVDGLLDRETISQYDVTIVATDEGTPPLSSTAVISVQI 769

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN-VD 306
             DVNDNAPRF        + EN  +G  I R  A DAD   NA+LTY++ D       + 
Sbjct: 770  SDVNDNAPRFMDENLNIYIKENSRVGDIITRASAQDADVNDNAKLTYSLLDSHQKDVLIS 829

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
              + I+  +G + +    + E    +Q  V ATD G PP S+  T               
Sbjct: 830  TVVNINSATGDIISLQSFNYEELKTFQFKVQATDSGVPPLSSNVTVNVFILDENDNSPTI 889

Query: 367  MPGQYEVELAEDEP------PGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQN 418
            +    E      E        G  V  + A DAD      L Y ++       F + +  
Sbjct: 890  LAPYSEHGSVNSESIPYSAEAGYFVAKIRAVDADSGYNALLSYHLSEPKGNNLFRMGTST 949

Query: 419  GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV---FENAPYT 475
            G   I   + +     + + L V  +D+G  S +A V I +    + A +   F + P  
Sbjct: 950  GE--IRTKRRMSDNDLKTHPLVVLVSDNGDPSLSATVSIEVVVVESAADIQTQFRHVPMK 1007

Query: 476  ASVFEDAPIGTTV-LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
               F D  +   + +V++ATD D G N +I YS     +++        F +N  TG I 
Sbjct: 1008 EESFSDLNLYLLIAIVLNATDLDEGQNGKIKYSFIKRGNSDP----SNIFDLNSDTGEIK 1063

Query: 535  TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
                LD E    Y + V A D G    S    + I ++D NDN P          + EDA
Sbjct: 1064 VKGELDYEETPAYEVRVQANDQGTTPRSAHAKLLIEIIDENDNAPEISVTSLMTPLKEDA 1123

Query: 595  LVGTSVSQVGATDADVGLNG--------RIHYELDPKDREEGSFVIDPASGVIRTNKALD 646
             +GT V+ +   D D G NG         + ++L    + E S V+D A         LD
Sbjct: 1124 ELGTIVALITVNDKDGGKNGVAVCKVVGSVPFKLKSNYKNEYSLVVDGA---------LD 1174

Query: 647  RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706
            RE+ + +++   A D G PP S+  ++ + I D+ND+ PVF    +  Y+ ENS  G+ I
Sbjct: 1175 RENTSVYNVTVQATDEGDPPLSTIKVITVHISDVNDNAPVFMVPVINVYLRENSQTGSVI 1234

Query: 707  GEIRAHDPDEGPNAVVHYSI 726
              I A DPD   NA V Y++
Sbjct: 1235 DTISAVDPDLDHNAKVIYTL 1254



 Score =  264 bits (647), Expect = 2e-68
 Identities = 228/808 (28%), Positives = 357/808 (44%), Gaps = 61/808 (7%)

Query: 13   VLDCNDHSPVFEMQQYE------ASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            +LD ND+SP       E       S+   A +G  V  ++A D D G NA + Y +    
Sbjct: 334  ILDENDNSPTILAPYSEHGSVNSESIPYSAEAGYFVAKIRAVDADSGYNALLSYHLS--- 390

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
                 P+              ++FR+   +G + T+  +    +  + ++V  +D   P 
Sbjct: 391  ----EPKG------------NNLFRMGTSTGEIRTKRRMSDNDLKTHPLVVLVSDNGDP- 433

Query: 127  SDRLSSTATIHVNIIDDN-DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA-DVGAN 184
               LS+T +I V +++   D   QF           D+++     I  + A    + G+N
Sbjct: 434  --SLSATVSIEVVVVESAADIQTQFRHVPMKEESFSDLNLYLLIAIVSVSAIFLLNTGSN 491

Query: 185  SAIRYAIIGG---NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
            S   Y I      +  +    D  S ++ L K LD E+    +L + A DGG P+RS T 
Sbjct: 492  SVKAYKISANEHFSVDVSSGADGTSAELVLEKALDREKQALIKLTLTAVDGGKPARSGTL 551

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
            Q+L+N+ DVNDN P F  SL++  VSE VP+G  I+++ A D DEG N +L Y++  +  
Sbjct: 552  QILVNVIDVNDNTPVFSQSLYKVRVSEGVPVGTQILKLNANDLDEGSNGDLRYSLMKR-- 609

Query: 302  TGNVDL-PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
             GNV+    ++DP SG +     LD E    Y+L V ATD G  PRS  +          
Sbjct: 610  -GNVNSEKFSVDPESGEIVVKASLDYEESGAYELRVQATDQGASPRSGYSKVLVEVLDVN 668

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420
                          + E    GT V  ++ TD D     H      ++      ++    
Sbjct: 669  DNAPEISVTSLMSPIKESAGLGTVVALVSVTDKDGGQNGHLSCKIRDSSPFALKSNYKSY 728

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASV 478
              + V   LD +   +Y +T+ ATD G    S TA++ + I+D N+ AP F +      +
Sbjct: 729  YSLVVDGLLDRETISQYDVTIVATDEGTPPLSSTAVISVQISDVNDNAPRFMDENLNIYI 788

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             E++ +G  +   SA D+DV  NA++TYSL      + +        IN  TG I + + 
Sbjct: 789  KENSRVGDIITRASAQDADVNDNAKLTYSLLDSHQKDVLI--STVVNINSATGDIISLQS 846

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF------KQQLYTANIME 592
             + E +  +   V A D GVP LS    V + ++D NDN P           + + +I  
Sbjct: 847  FNYEELKTFQFKVQATDSGVPPLSSNVTVNVFILDENDNSPTILAPYSEHGSVNSESIPY 906

Query: 593  DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652
             A  G  V+++ A DAD G N  + Y L  + +    F +  ++G IRT + +    + T
Sbjct: 907  SAEAGYFVAKIRAVDADSGYNALLSYHLS-EPKGNNLFRMGTSTGEIRTKRRMSDNDLKT 965

Query: 653  HDLKAVAIDGGTPPQSSTVIVH-IKIEDINDSPPVFESDCLTFYISENSPIGTTIG-EIR 710
            H L  +  D G P  S+TV +  + +E   D    F    +      +  +   I   + 
Sbjct: 966  HPLVVLVSDNGDPSLSATVSIEVVVVESAADIQTQFRHVPMKEESFSDLNLYLLIAIVLN 1025

Query: 711  AHDPDEGPNAVVHYS-IKGG--DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
            A D DEG N  + YS IK G  D SN F L     SD  E+    +LDYE     YE+ +
Sbjct: 1026 ATDLDEGQNGKIKYSFIKRGNSDPSNIFDL----NSDTGEIKVKGELDYEE-TPAYEVRV 1080

Query: 768  RA---ASPPLWNDVRVEILVTDVNDNAP 792
            +A    + P     ++ I + D NDNAP
Sbjct: 1081 QANDQGTTPRSAHAKLLIEIIDENDNAP 1108



 Score =  206 bits (504), Expect = 5e-51
 Identities = 179/658 (27%), Positives = 291/658 (44%), Gaps = 34/658 (5%)

Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
           +S   Q+ IN+ DVNDN P F  SL++  V EN  +G +I+ + A D D+GVN EL Y+ 
Sbjct: 2   KSGNLQIRINVIDVNDNYPLFSKSLYKVQVVENANVGATILTLSATDLDDGVNGELVYSF 61

Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
            ++    N +    ++  +G +   G +D E    Y++ V A D G PPR+A +      
Sbjct: 62  AERG-RFNPEDKFALNAHNGEITLKGNIDYEENPAYEIRVQARDKGAPPRTAHSKVLVEV 120

Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSI 414
                             + ED   GT V  +T  D D  ++   +  IT G+       
Sbjct: 121 IDVNDNAPEISVSSLMSPVKEDAGLGTAVAMVTINDRDGGKNGLTNCRIT-GSVPFMLKS 179

Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENA 472
             +N   L+ V  PLD +   +Y +T++A D G  S   T ++ + I+D N+  P F ++
Sbjct: 180 NYKNYYSLV-VDGPLDRETASQYNVTITAEDEGTPSLTGTTIINVQISDVNDNPPRFPDS 238

Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
                + E++P+G+TV  ++  DSD+  NA+ TY L +      VA       IN +TG 
Sbjct: 239 LLNVYLKENSPVGSTVHRLTTLDSDLNENAKATYHLLNNSPKSGVA---AMININSETGD 295

Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF------KQQLY 586
           I + +  + E +  +   V A D GVP LS    V + ++D NDN P           + 
Sbjct: 296 IISLQSFNYEELKTFQFKVQATDSGVPPLSSNVTVNVFILDENDNSPTILAPYSEHGSVN 355

Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646
           + +I   A  G  V+++ A DAD G N  + Y L  + +    F +  ++G IRT + + 
Sbjct: 356 SESIPYSAEAGYFVAKIRAVDADSGYNALLSYHLS-EPKGNNLFRMGTSTGEIRTKRRMS 414

Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVH-IKIEDINDSPPVFESDCL--TFYISENSPIG 703
              + TH L  +  D G P  S+TV +  + +E   D    F    +    +   N  + 
Sbjct: 415 DNDLKTHPLVVLVSDNGDPSLSATVSIEVVVVESAADIQTQFRHVPMKEESFSDLNLYLL 474

Query: 704 TTIGEIRA-HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD--KAELVTMVDLDYESPR 760
             I  + A    + G N+V  Y I   +    FS++   G+D   AELV    LD E   
Sbjct: 475 IAIVSVSAIFLLNTGSNSVKAYKISANE---HFSVDVSSGADGTSAELVLEKALDREKQA 531

Query: 761 --KKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVP 817
             K     +    P     +++ + V DVNDN PV     +      +  PVG    ++ 
Sbjct: 532 LIKLTLTAVDGGKPARSGTLQILVNVIDVNDNTPVFSQ-SLYKVRVSEGVPVGTQILKLN 590

Query: 818 AYDAD--VTDKLQYRILS-GN-NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
           A D D      L+Y ++  GN N+    ++  +G + +   L+        + V  TD
Sbjct: 591 ANDLDEGSNGDLRYSLMKRGNVNSEKFSVDPESGEIVVKASLDYEESGAYELRVQATD 648



 Score = 63.7 bits (148), Expect = 7e-08
 Identities = 42/133 (31%), Positives = 68/133 (51%), Gaps = 11/133 (8%)

Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
           P+S  + + I + D+ND+ P+F        + EN+ +G TI  + A D D+G N  + YS
Sbjct: 1   PKSGNLQIRINVIDVNDNYPLFSKSLYKVQVVENANVGATILTLSATDLDDGVNGELVYS 60

Query: 726 I--KGG-DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVR 779
              +G  +  + F+L    G    E+    ++DYE     YE+ ++A    +PP     +
Sbjct: 61  FAERGRFNPEDKFALNAHNG----EITLKGNIDYEE-NPAYEIRVQARDKGAPPRTAHSK 115

Query: 780 VEILVTDVNDNAP 792
           V + V DVNDNAP
Sbjct: 116 VLVEVIDVNDNAP 128


>UniRef50_UPI00006A2595 Cluster: Protocadherin-16 precursor
            (Dachsous-1) (Cadherin-19) (Fibroblast cadherin 1).; n=2;
            Xenopus tropicalis|Rep: Protocadherin-16 precursor
            (Dachsous-1) (Cadherin-19) (Fibroblast cadherin 1). -
            Xenopus tropicalis
          Length = 2375

 Score =  322 bits (792), Expect = 7e-86
 Identities = 238/740 (32%), Positives = 370/740 (50%), Gaps = 70/740 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I++LD ND++P F++ +Y A  +E    G+ ++ + A D D G N +V Y+ +   A   
Sbjct: 1236 ISLLDLNDNAPRFQLPRYTAYTQEAQPDGSPLIQVLAEDPDQGLNGQVTYSFDQSQA--- 1292

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           ++D+FRID ++GA+ T A LDRE  ++  ++V ATD+ SP    L
Sbjct: 1293 ---------------MKDLFRIDPQTGAITTAAILDREIWSQAHLVVIATDRGSP---PL 1334

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK--IKATDADVGANSAIR 188
            +S+AT+ V + D NDN P       T  +  ++SV ++ VI    ++ T  DV +  A+ 
Sbjct: 1335 TSSATLTVLVTDVNDNSP-------TTPLQLELSVPEDAVIGSEILQVTGNDVDSGPALS 1387

Query: 189  YA-IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            Y  ++ G  +  F++    G + L + LDYE  +SY L ++  DG         +L + +
Sbjct: 1388 YTLLVDGAMEGAFTMLRYGGQIWLSRQLDYEDRKSYSLTVQTSDG---KHLTHAELTLTL 1444

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            +DVNDN+P F  SL+Q S+ E+   G  +  V+A D D G N  ++Y +        V  
Sbjct: 1445 QDVNDNSPEFGKSLYQVSILEHAAAGTPLFTVRATDRDSGDNGRVSYRVLSP-----VGG 1499

Query: 308  PITIDPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
               I P +G ++ +  ++ + Q+    +LV A D G P  ++  T              F
Sbjct: 1500 AFHIHPDNGTLFANKLVELDPQSPLVDVLVEARDHGSPSLASLTTVQFLVVDANDHSPTF 1559

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITS----QNG 419
               QY   + ED P G+ V+ L  TDAD   E+  L Y I  GNT   F + S     NG
Sbjct: 1560 SQSQYSASVPEDLPLGSTVLILEVTDADFTQENAALDYTILSGNTDNAFQVQSGMRFWNG 1619

Query: 420  R----GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAP 473
            R    G I +   LDF+    Y LT+ A+D G   RS +  V IN+ D N+  PVF    
Sbjct: 1620 RFQQIGSIILTDSLDFEAISFYNLTLGASDRGVPQRSHSVPVLINVLDINDNPPVFPRPL 1679

Query: 474  YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
            Y+  + E+AP+G+ VL V A DSD G N  + YS++S           + F IN  TGAI
Sbjct: 1680 YSVLLSEEAPVGSEVLRVLAQDSDSGSNGLVHYSITS-------GDESRLFQINEATGAI 1732

Query: 534  TTNKLLDRETMSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592
               + LDRE  + + L V A DG G  +      V I V D+NDN+P F  Q+ T +I E
Sbjct: 1733 RLARHLDRERQALHALVVLALDGQGGQANFALVPVTIEVRDINDNKPYFPVQILTTSIRE 1792

Query: 593  DALVGTSVSQVGATDADVGLNGRIHYE-LDPKDREEG------SFVIDPASGVIRTNKAL 645
            +    T ++++ A D D G+ G++ Y  LD      G       FV++  SG +R+ ++ 
Sbjct: 1793 NQPANTPLTKIHAIDLDTGVYGQLFYTMLDLAVAGSGMLMGKDMFVVNRTSGELRSKQSF 1852

Query: 646  DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
            D E +   ++   A+D G    S+TV V + +   ++  PVF S    F + E +  G +
Sbjct: 1853 DYERIKVFNMVVKAMDAGN--FSATVTVQVLVTGEDEYNPVFISPFFNFEVPEGAVKGES 1910

Query: 706  IGEIRAHDPDEGPNAVVHYS 725
            +G ++A D DEG + VV YS
Sbjct: 1911 LGHVQATDEDEGADGVVLYS 1930



 Score =  296 bits (727), Expect = 5e-78
 Identities = 245/764 (32%), Positives = 357/764 (46%), Gaps = 36/764 (4%)

Query: 103  ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162
            A LD E+  R+ ++++A  Q         S AT+ ++++D NDN P+F    YT    E 
Sbjct: 1207 AMLDYEQNPRHKLVLQAETQQH------LSFATLTISLLDLNDNAPRFQLPRYTAYTQE- 1259

Query: 163  ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ-FSIDSLSGDVSLVKTLDYEQVR 221
             +  D   + ++ A D D G N  + Y+          F ID  +G ++    LD E   
Sbjct: 1260 -AQPDGSPLIQVLAEDPDQGLNGQVTYSFDQSQAMKDLFRIDPQTGAITTAAILDREIWS 1318

Query: 222  SYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA 281
               LV+ A D GSP  +++  L + + DVNDN+P     L + SV E+  IG  I++V  
Sbjct: 1319 QAHLVVIATDRGSPPLTSSATLTVLVTDVNDNSPTTPLQL-ELSVPEDAVIGSEILQVTG 1377

Query: 282  YDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341
             D D G    L+YT+      G ++   T+    G ++ S QLD E +  Y L V  +DG
Sbjct: 1378 NDVDSG--PALSYTLL---VDGAMEGAFTMLRYGGQIWLSRQLDYEDRKSYSLTVQTSDG 1432

Query: 342  GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DN-RL 399
                    A               F    Y+V + E    GTP+ T+ ATD D  DN R+
Sbjct: 1433 ---KHLTHAELTLTLQDVNDNSPEFGKSLYQVSILEHAAAGTPLFTVRATDRDSGDNGRV 1489

Query: 400  HYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM--VQI 457
             Y +      G F I   NG         LD +     VL V A D G  S  ++  VQ 
Sbjct: 1490 SYRVLSP-VGGAFHIHPDNGTLFANKLVELDPQSPLVDVL-VEARDHGSPSLASLTTVQF 1547

Query: 458  NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYS-LSSEISNE 515
             + DAN+++P F  + Y+ASV ED P+G+TVL++  TD+D    NA + Y+ LS    N 
Sbjct: 1548 LVVDANDHSPTFSQSQYSASVPEDLPLGSTVLILEVTDADFTQENAALDYTILSGNTDNA 1607

Query: 516  AVAHHDQQFVIN--PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
                   +F      Q G+I     LD E +S Y LT+ A D GVP  S +  V I+V+D
Sbjct: 1608 FQVQSGMRFWNGRFQQIGSIILTDSLDFEAISFYNLTLGASDRGVPQRSHSVPVLINVLD 1667

Query: 574  VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633
            +NDN PVF + LY+  + E+A VG+ V +V A D+D G NG +HY +   D E   F I+
Sbjct: 1668 INDNPPVFPRPLYSVLLSEEAPVGSEVLRVLAQDSDSGSNGLVHYSITSGD-ESRLFQIN 1726

Query: 634  PASGVIRTNKALDRESVATHDLKAVAIDG-GTPPQSSTVIVHIKIEDINDSPPVFESDCL 692
             A+G IR  + LDRE  A H L  +A+DG G     + V V I++ DIND+ P F    L
Sbjct: 1727 EATGAIRLARHLDRERQALHALVVLALDGQGGQANFALVPVTIEVRDINDNKPYFPVQIL 1786

Query: 693  TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ----GSDKAEL 748
            T  I EN P  T + +I A D D G    + Y++     + S  L  +          EL
Sbjct: 1787 TTSIRENQPANTPLTKIHAIDLDTGVYGQLFYTMLDLAVAGSGMLMGKDMFVVNRTSGEL 1846

Query: 749  VTMVDLDYESPRKKYELVIRAASPPLWN-DVRVEILVTDVNDNAPVMKDFQIIFNNYKDC 807
             +    DYE   K + +V++A     ++  V V++LVT  ++  PV       F   +  
Sbjct: 1847 RSKQSFDYER-IKVFNMVVKAMDAGNFSATVTVQVLVTGEDEYNPVFISPFFNFEVPEGA 1905

Query: 808  FPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTL 851
                  G V A D D              +    +NETTG++ L
Sbjct: 1906 VKGESLGHVQATDEDEGADGVVLYSFSKPSPYFGINETTGNIYL 1949



 Score =  286 bits (701), Expect = 7e-75
 Identities = 217/749 (28%), Positives = 360/749 (48%), Gaps = 51/749 (6%)

Query: 177  TDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGS 234
            T   +G+   +      GN ++  S+   +G +++ +   LDYEQ   ++LV++A+   +
Sbjct: 1169 THVHMGSMGTVWAQYGNGNARVCGSLVPPAGQITVAQAAMLDYEQNPRHKLVLQAE---T 1225

Query: 235  PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294
                +   L I++ D+NDNAPRF    +     E  P G  +++V A D D+G+N ++TY
Sbjct: 1226 QQHLSFATLTISLLDLNDNAPRFQLPRYTAYTQEAQPDGSPLIQVLAEDPDQGLNGQVTY 1285

Query: 295  TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354
            +        ++     IDP++G + T+  LDRE  ++  L+V ATD G PP +++AT   
Sbjct: 1286 SFDQSQAMKDL---FRIDPQTGAITTAAILDREIWSQAHLVVIATDRGSPPLTSSATLTV 1342

Query: 355  XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEI-TGGNTRGRFS 413
                         P Q E+ + ED   G+ ++ +T  D D    L Y +   G   G F+
Sbjct: 1343 LVTDVNDNSPT-TPLQLELSVPEDAVIGSEILQVTGNDVDSGPALSYTLLVDGAMEGAFT 1401

Query: 414  ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAP 473
            +    G+  I +++ LD++  + Y LTV  +D G     A + + + D N+ +P F  + 
Sbjct: 1402 MLRYGGQ--IWLSRQLDYEDRKSYSLTVQTSD-GKHLTHAELTLTLQDVNDNSPEFGKSL 1458

Query: 474  YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
            Y  S+ E A  GT +  V ATD D G N +++Y + S +           F I+P  G +
Sbjct: 1459 YQVSILEHAAAGTPLFTVRATDRDSGDNGRVSYRVLSPVGGA--------FHIHPDNGTL 1510

Query: 534  TTNKLLDRETMSGYL-LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592
              NKL++ +  S  + + V ARD G PSL+  T V+  VVD ND+ P F Q  Y+A++ E
Sbjct: 1511 FANKLVELDPQSPLVDVLVEARDHGSPSLASLTTVQFLVVDANDHSPTFSQSQYSASVPE 1570

Query: 593  DALVGTSVSQVGATDADVGL-NGRIHYELDPKDREEGSFVIDPAS----------GVIRT 641
            D  +G++V  +  TDAD    N  + Y +      + +F +              G I  
Sbjct: 1571 DLPLGSTVLILEVTDADFTQENAALDYTI-LSGNTDNAFQVQSGMRFWNGRFQQIGSIIL 1629

Query: 642  NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701
              +LD E+++ ++L   A D G P +S +V V I + DIND+PPVF     +  +SE +P
Sbjct: 1630 TDSLDFEAISFYNLTLGASDRGVPQRSHSVPVLINVLDINDNPPVFPRPLYSVLLSEEAP 1689

Query: 702  IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761
            +G+ +  + A D D G N +VHYSI  GD+S  F +    G+    L   +D + ++   
Sbjct: 1690 VGSEVLRVLAQDSDSGSNGLVHYSITSGDESRLFQINEATGA--IRLARHLDRERQALHA 1747

Query: 762  KYELVIRA-ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAY 819
               L +        +  V V I V D+NDN P     QI+  + ++  P   P  ++ A 
Sbjct: 1748 LVVLALDGQGGQANFALVPVTIEVRDINDNKPYF-PVQILTTSIRENQPANTPLTKIHAI 1806

Query: 820  DAD--VTDKLQYRIL------SG--NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSV 869
            D D  V  +L Y +L      SG     ++ ++N T+G +      +    K+  M V  
Sbjct: 1807 DLDTGVYGQLFYTMLDLAVAGSGMLMGKDMFVVNRTSGELRSKQSFDYERIKVFNMVVKA 1866

Query: 870  TDGVNEIKAMMQLSVRLITEEMLLNSITV 898
             D  N   A + + V L+T E   N + +
Sbjct: 1867 MDAGN-FSATVTVQV-LVTGEDEYNPVFI 1893



 Score =  255 bits (624), Expect = 1e-65
 Identities = 206/694 (29%), Positives = 326/694 (46%), Gaps = 54/694 (7%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F I+  SG L  R +LDRE    Y + V A+  A P +   ++T T+ V + D+NDN P+
Sbjct: 209 FSIEADSGWLYVRGALDRESREAYVLAVLAS--AGPGTR--TATCTVRVRVTDENDNSPR 264

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209
            SE+ + +S  E+    +   + ++ ATD D G N  + Y +     +  F I+  +G++
Sbjct: 265 LSEERFFLSATENRPPGET--VGRVSATDRDAGPNGRVSYRL--PPLESDFHINPHTGEL 320

Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF-YTSLFQE---S 265
           S  + LD E   +Y+L++ AQDGG+P RS T  + I + D NDNAP F + +  +E    
Sbjct: 321 STRRVLDRELQATYQLLVIAQDGGAPPRSVTGTVHITVLDENDNAPTFLHPNAGKEISLQ 380

Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN--VDLPITIDPRSGWVYTSGQ 323
           V E    G  I  +QA D DEG N  +TY++    Y  +  V  P+ +      +++   
Sbjct: 381 VMEGKKSGMFIASLQAKDPDEGENGTVTYSLAGTGYKTDRLVVAPLAVALAPPPIHSMPM 440

Query: 324 LDRETQAKYQLLVTATDGGDPPR--SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381
            D             T    PP   + T                  P    +   E   P
Sbjct: 441 HD---------FSPPTPPSWPPHVFNVTPFTAFQVIPASRYPSKSNPSSLVLSPMEGLAP 491

Query: 382 GTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441
           G+ + +L A      +R++  +      G F +  Q G   I +   LDF+ + R+   V
Sbjct: 492 GSLLGSL-APRMPHGSRIYTLLD--EPHGIFMVDGQTGS--IFLVGELDFESQPRFSFRV 546

Query: 442 SATDSGGRS------DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495
           S  +    S          +++ + D N+++P F   P T  V EDA +G++V    A+D
Sbjct: 547 SVEEVREASLGYVPPHVVHIEVEVQDRNDHSPAFPEDPLTLVVPEDAHVGSSVFTFQASD 606

Query: 496 SD-VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554
            D  G N+Q+ YSL  +            F ++ +TG +   + LDRE +S YLL V A 
Sbjct: 607 HDGPGPNSQVRYSLLRQDPGSP----GSTFRLDAETGVLYVAQALDREEVSSYLLVVEAS 662

Query: 555 DGGV---PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG 611
           D  V      S +    + + D ND+ P F   L    + ED  VG++   + A D D+G
Sbjct: 663 DQAVNVSQQRSTSVTARVFISDRNDHAPQFITPLVVW-LPEDLPVGSTAIYMVAQDPDLG 721

Query: 612 LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671
            NG++ Y+L     +EG F + P+SG +   + LDRE+   ++L  VA+D G+P  SST 
Sbjct: 722 DNGKVGYQL-VGGNDEGKFQLHPSSGALTVVRTLDRETTEGYNLTVVAMDHGSPRLSSTQ 780

Query: 672 IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD 731
            + + + D+ND  P FE       + EN P+GTT+  + A D D G +  V Y   GG  
Sbjct: 781 TLSVSLLDVNDEAPSFEKPQYDAQVQENQPVGTTVLRVVALDRDLGQSGRVTY---GGVS 837

Query: 732 SNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765
            + F+L+   G     L T V LD E+ ++ Y+L
Sbjct: 838 GDEFALDPETG----VLTTKVPLDREA-KELYKL 866



 Score =  190 bits (462), Expect = 6e-46
 Identities = 209/772 (27%), Positives = 334/772 (43%), Gaps = 71/772 (9%)

Query: 194 GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDN 253
           G+ +   S+D  SG +SLV+ LD EQ     L ++ + G  P+ +   +L + I DVNDN
Sbjct: 3   GDPRGLLSLDPHSGLLSLVRPLDREQTEKLLLEVQGRSGAPPAYARA-RLTLYITDVNDN 61

Query: 254 APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313
            P F +      +   +PIG  I R QA D D G N ++ Y +   D  G    P +ID 
Sbjct: 62  PPAFPSPFHTLRLQSPIPIGSVIFRAQATDPDTGFNGQVYYEL---DSPG----PFSIDG 114

Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373
            SG +  +G L +E   +Y + V A+DGG P  S+ A                    Y V
Sbjct: 115 -SGQLRATGLLSQE---RYDVRVLASDGGTPQLSS-ALELTVLLMELQKEPACGASDYRV 169

Query: 374 ELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432
           E+ E  PP + ++ + A      + +L Y +        FSI + +G   + V   LD +
Sbjct: 170 EVREGSPPLSRLLQVRAQPPGAGEGQLIYRLRPDADAVGFSIEADSG--WLYVRGALDRE 227

Query: 433 QERRYVLTVSATDSGG-RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491
               YVL V A+   G R+ T  V++ +TD N+ +P      +  S  E+ P G TV  V
Sbjct: 228 SREAYVLAVLASAGPGTRTATCTVRVRVTDENDNSPRLSEERFFLSATENRPPGETVGRV 287

Query: 492 SATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTV 551
           SATD D G N +++Y L    S+         F INP TG ++T ++LDRE  + Y L V
Sbjct: 288 SATDRDAGPNGRVSYRLPPLESD---------FHINPHTGELSTRRVLDRELQATYQLLV 338

Query: 552 TARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ----QLYTANIMEDALVGTSVSQVGATD 607
            A+DGG P  S T  V I+V+D NDN P F      +  +  +ME    G  ++ + A D
Sbjct: 339 IAQDGGAPPRSVTGTVHITVLDENDNAPTFLHPNAGKEISLQVMEGKKSGMFIASLQAKD 398

Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
            D G NG + Y L     +    V+ P +  +         S+  HD  +       PP 
Sbjct: 399 PDEGENGTVTYSLAGTGYKTDRLVVAPLAVALAPPPI---HSMPMHDF-SPPTPPSWPPH 454

Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
              V      + I  S    +S+  +  +S     G   G +        P+    Y++ 
Sbjct: 455 VFNVTPFTAFQVIPASRYPSKSNPSSLVLSPME--GLAPGSLLGSLAPRMPHGSRIYTLL 512

Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYES-PRKKYEL---VIRAAS----PPLWNDVR 779
             +    F ++ + GS    +  + +LD+ES PR  + +    +R AS    PP  + V 
Sbjct: 513 -DEPHGIFMVDGQTGS----IFLVGELDFESQPRFSFRVSVEEVREASLGYVPP--HVVH 565

Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD---VTDKLQYRIL---S 833
           +E+ V D ND++P   +  +     +D           A D D      +++Y +L    
Sbjct: 566 IEVEVQDRNDHSPAFPEDPLTLVVPEDAHVGSSVFTFQASDHDGPGPNSQVRYSLLRQDP 625

Query: 834 GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLL 893
           G+  +   L+  TG + ++  L+        + V  +D    +      SV   T  + +
Sbjct: 626 GSPGSTFRLDAETGVLYVAQALDREEVSSYLLVVEASDQAVNVSQQRSTSV---TARVFI 682

Query: 894 NSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGN 945
           +      ND  A QF++PL+ +  + L      P  +  I+ V  D D+  N
Sbjct: 683 SD----RND-HAPQFITPLVVWLPEDL------PVGSTAIYMVAQDPDLGDN 723



 Score =  186 bits (453), Expect = 8e-45
 Identities = 214/824 (25%), Positives = 351/824 (42%), Gaps = 75/824 (9%)

Query: 92  IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151
           +D  SG L     LDRE+  +  + V+    A P   R    A + + I D NDN P F 
Sbjct: 11  LDPHSGLLSLVRPLDREQTEKLLLEVQGRSGAPPAYAR----ARLTLYITDVNDNPPAFP 66

Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSL 211
              +T+ +   I +    VI + +ATD D G N  + Y +   ++   FSID  SG +  
Sbjct: 67  SPFHTLRLQSPIPI--GSVIFRAQATDPDTGFNGQVYYEL---DSPGPFSIDG-SGQLRA 120

Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271
              L  E+   Y + + A DGG+P  S+  +L + + ++    P    S ++  V E  P
Sbjct: 121 TGLLSQER---YDVRVLASDGGTPQLSSALELTVLLMEL-QKEPACGASDYRVEVREGSP 176

Query: 272 IGYSIVRVQAYDADEGVNAELTYTM-TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA 330
               +++V+A     G   +L Y +  D D  G      +I+  SGW+Y  G LDRE++ 
Sbjct: 177 PLSRLLQVRAQPPGAG-EGQLIYRLRPDADAVG-----FSIEADSGWLYVRGALDRESRE 230

Query: 331 KYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTA 390
            Y L V A+  G   R+AT T                  ++ +   E+ PPG  V  ++A
Sbjct: 231 AYVLAVLAS-AGPGTRTATCTVRVRVTDENDNSPRLSEERFFLSATENRPPGETVGRVSA 289

Query: 391 TDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG 448
           TD D   + R+ Y +        F I    G   ++  + LD + +  Y L V A D G 
Sbjct: 290 TDRDAGPNGRVSYRLP--PLESDFHINPHTGE--LSTRRVLDRELQATYQLLVIAQDGGA 345

Query: 449 --RSDTAMVQINITDANNYAPVF--ENA--PYTASVFEDAPIGTTVLVVSATDSDVGINA 502
             RS T  V I + D N+ AP F   NA    +  V E    G  +  + A D D G N 
Sbjct: 346 PPRSVTGTVHITVLDENDNAPTFLHPNAGKEISLQVMEGKKSGMFIASLQAKDPDEGENG 405

Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
            +TYSL+         +   + V+ P   A+    +    +M  +  +        P + 
Sbjct: 406 TVTYSLA------GTGYKTDRLVVAPLAVALAPPPI---HSMPMHDFSPPTPPSWPPHVF 456

Query: 563 DTTD-VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621
           + T      V+  +             + ME    G   S +G+    +    RI+  L 
Sbjct: 457 NVTPFTAFQVIPASRYPSKSNPSSLVLSPMEGLAPG---SLLGSLAPRMPHGSRIYTLL- 512

Query: 622 PKDREEGSFVIDPASGVIRTNKALDRES-------VATHDLKAVAIDGGTPPQSSTVIVH 674
             D   G F++D  +G I     LD ES       V+  +++  ++ G  PP    V + 
Sbjct: 513 --DEPHGIFMVDGQTGSIFLVGELDFESQPRFSFRVSVEEVREASL-GYVPPH--VVHIE 567

Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSN 733
           ++++D ND  P F  D LT  + E++ +G+++   +A D D  GPN+ V YS+   D  +
Sbjct: 568 VEVQDRNDHSPAFPEDPLTLVVPEDAHVGSSVFTFQASDHDGPGPNSQVRYSLLRQDPGS 627

Query: 734 SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA------SPPLWNDVRVEILVTDV 787
             S   R  ++   L     LD E     Y LV+ A+      S      V   + ++D 
Sbjct: 628 PGS-TFRLDAETGVLYVAQALDREEV-SSYLLVVEASDQAVNVSQQRSTSVTARVFISDR 685

Query: 788 NDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVTD--KLQYRILSGNNANLILLNE 844
           ND+AP      +++    +  PVG     + A D D+ D  K+ Y+++ GN+     L+ 
Sbjct: 686 NDHAPQFITPLVVW--LPEDLPVGSTAIYMVAQDPDLGDNGKVGYQLVGGNDEGKFQLHP 743

Query: 845 TTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLI 887
           ++G++T+   L+    +   + V   D G   + +   LSV L+
Sbjct: 744 SSGALTVVRTLDRETTEGYNLTVVAMDHGSPRLSSTQTLSVSLL 787



 Score =  185 bits (450), Expect = 2e-44
 Identities = 116/332 (34%), Positives = 173/332 (52%), Gaps = 27/332 (8%)

Query: 4   PFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTI 62
           P  +H ++ V D NDHSP F        V E A  G++V T +A+D D  G N++V Y+ 
Sbjct: 561 PHVVHIEVEVQDRNDHSPAFPEDPLTLVVPEDAHVGSSVFTFQASDHDGPGPNSQVRYS- 619

Query: 63  ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122
            L+  D  +P                 FR+D  +G L    +LDRE+V+ Y ++V+A+DQ
Sbjct: 620 -LLRQDPGSP--------------GSTFRLDAETGVLYVAQALDREEVSSYLLVVEASDQ 664

Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
           A  VS + S++ T  V I D ND+ PQF      V + ED+ V    +   + A D D+G
Sbjct: 665 AVNVSQQRSTSVTARVFISDRNDHAPQFI-TPLVVWLPEDLPVGSTAIY--MVAQDPDLG 721

Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
            N  + Y ++GGN + +F +   SG +++V+TLD E    Y L + A D GSP  S+T  
Sbjct: 722 DNGKVGYQLVGGNDEGKFQLHPSSGALTVVRTLDRETTEGYNLTVVAMDHGSPRLSSTQT 781

Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
           L +++ DVND AP F    +   V EN P+G +++RV A D D G +  +TY     D  
Sbjct: 782 LSVSLLDVNDEAPSFEKPQYDAQVQENQPVGTTVLRVVALDRDLGQSGRVTYGGVSGD-- 839

Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQL 334
                   +DP +G + T   LDRE +  Y+L
Sbjct: 840 -----EFALDPETGVLTTKVPLDREAKELYKL 866



 Score =  171 bits (417), Expect = 2e-40
 Identities = 118/392 (30%), Positives = 185/392 (47%), Gaps = 22/392 (5%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDI-GKNAEVEYTIELVTAD 68
            Q  V+D NDHSP F   QY ASV E    G+TVL L+ TD D   +NA ++YTI  ++ +
Sbjct: 1546 QFLVVDANDHSPTFSQSQYSASVPEDLPLGSTVLILEVTDADFTQENAALDYTI--LSGN 1603

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
            T N               Q +       G+++   SLD E ++ Y + + A+D+  P   
Sbjct: 1604 TDNAFQVQSGMRFWNGRFQQI-------GSIILTDSLDFEAISFYNLTLGASDRGVP--- 1653

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            + S +  + +N++D NDN P F    Y+V + E+  V     + ++ A D+D G+N  + 
Sbjct: 1654 QRSHSVPVLINVLDINDNPPVFPRPLYSVLLSEEAPVGSE--VLRVLAQDSDSGSNGLVH 1711

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG-GSPSRSNTTQLLINI 247
            Y+I  G+    F I+  +G + L + LD E+   + LV+ A DG G  +      + I +
Sbjct: 1712 YSITSGDESRLFQINEATGAIRLARHLDRERQALHALVVLALDGQGGQANFALVPVTIEV 1771

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            RD+NDN P F   +   S+ EN P    + ++ A D D GV  +L YTM D    G+  L
Sbjct: 1772 RDINDNKPYFPVQILTTSIRENQPANTPLTKIHAIDLDTGVYGQLFYTMLDLAVAGSGML 1831

Query: 308  ----PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
                   ++  SG + +    D E    + ++V A D G+   SAT T            
Sbjct: 1832 MGKDMFVVNRTSGELRSKQSFDYERIKVFNMVVKAMDAGN--FSATVTVQVLVTGEDEYN 1889

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395
              F+   +  E+ E    G  +  + ATD DE
Sbjct: 1890 PVFISPFFNFEVPEGAVKGESLGHVQATDEDE 1921



 Score =  154 bits (373), Expect = 4e-35
 Identities = 109/363 (30%), Positives = 176/363 (48%), Gaps = 26/363 (7%)

Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS----NTTQLLINIRDVNDNAP 255
           F +D  +G + LV  LD+E    +   +  ++    S      +   + + ++D ND++P
Sbjct: 519 FMVDGQTGSIFLVGELDFESQPRFSFRVSVEEVREASLGYVPPHVVHIEVEVQDRNDHSP 578

Query: 256 RFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYTGNVDLPITIDPR 314
            F        V E+  +G S+   QA D D  G N+++ Y++  +D  G+      +D  
Sbjct: 579 AFPEDPLTLVVPEDAHVGSSVFTFQASDHDGPGPNSQVRYSLLRQD-PGSPGSTFRLDAE 637

Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGG---DPPRSATATXXXXXXXXXXXXXXFMPGQY 371
           +G +Y +  LDRE  + Y L+V A+D        RS + T              F+    
Sbjct: 638 TGVLYVAQALDREEVSSYLLVVEASDQAVNVSQQRSTSVTARVFISDRNDHAPQFIT-PL 696

Query: 372 EVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
            V L ED P G+  + + A D D  ++ ++ Y++ GGN  G+F +   +G   +TV + L
Sbjct: 697 VVWLPEDLPVGSTAIYMVAQDPDLGDNGKVGYQLVGGNDEGKFQLHPSSGA--LTVVRTL 754

Query: 430 DFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
           D +    Y LTV A D G    S T  + +++ D N+ AP FE   Y A V E+ P+GTT
Sbjct: 755 DRETTEGYNLTVVAMDHGSPRLSSTQTLSVSLLDVNDEAPSFEKPQYDAQVQENQPVGTT 814

Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
           VL V A D D+G + ++TY     +S +       +F ++P+TG +TT   LDRE    Y
Sbjct: 815 VLRVVALDRDLGQSGRVTYG---GVSGD-------EFALDPETGVLTTKVPLDREAKELY 864

Query: 548 LLT 550
            LT
Sbjct: 865 KLT 867



 Score =  147 bits (357), Expect = 3e-33
 Identities = 109/362 (30%), Positives = 176/362 (48%), Gaps = 22/362 (6%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATD-QASPVSDRLSSTATIHVNIIDDNDNY 147
           +F +DG++G++     LD E   R++  V   + + + +         I V + D ND+ 
Sbjct: 518 IFMVDGQTGSIFLVGELDFESQPRFSFRVSVEEVREASLGYVPPHVVHIEVEVQDRNDHS 577

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSAIRYAIIG---GNTQMQFSID 203
           P F E   T+ V ED  V  +  +   +A+D D  G NS +RY+++    G+    F +D
Sbjct: 578 PAFPEDPLTLVVPEDAHVGSS--VFTFQASDHDGPGPNSQVRYSLLRQDPGSPGSTFRLD 635

Query: 204 SLSGDVSLVKTLDYEQVRSYRLVIRAQDGG---SPSRSNTTQLLINIRDVNDNAPRFYTS 260
           + +G + + + LD E+V SY LV+ A D     S  RS +    + I D ND+AP+F T 
Sbjct: 636 AETGVLYVAQALDREEVSSYLLVVEASDQAVNVSQQRSTSVTARVFISDRNDHAPQFITP 695

Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT 320
           L    + E++P+G + + + A D D G N ++ Y +      GN +    + P SG +  
Sbjct: 696 LVVW-LPEDLPVGSTAIYMVAQDPDLGDNGKVGYQLVG----GNDEGKFQLHPSSGALTV 750

Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380
              LDRET   Y L V A D G P  S+T T              F   QY+ ++ E++P
Sbjct: 751 VRTLDRETTEGYNLTVVAMDHGSPRLSSTQTLSVSLLDVNDEAPSFEKPQYDAQVQENQP 810

Query: 381 PGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYV 438
            GT V+ + A D D  +  R+ Y   GG +   F++  +   G++T   PLD + +  Y 
Sbjct: 811 VGTTVLRVVALDRDLGQSGRVTY---GGVSGDEFALDPET--GVLTTKVPLDREAKELYK 865

Query: 439 LT 440
           LT
Sbjct: 866 LT 867



 Score =  136 bits (330), Expect = 6e-30
 Identities = 117/393 (29%), Positives = 180/393 (45%), Gaps = 31/393 (7%)

Query: 404 TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT-AMVQINITDA 462
           + G+ RG  S+   +G  L+++ +PLD +Q  + +L V        +   A + + ITD 
Sbjct: 1   SSGDPRGLLSLDPHSG--LLSLVRPLDREQTEKLLLEVQGRSGAPPAYARARLTLYITDV 58

Query: 463 NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522
           N+  P F +  +T  +    PIG+ +    ATD D G N Q+ Y L S            
Sbjct: 59  NDNPPAFPSPFHTLRLQSPIPIGSVIFRAQATDPDTGFNGQVYYELDSP----------G 108

Query: 523 QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582
            F I+  +G +    LL +E    Y + V A DGG P LS   ++ + ++++   EP   
Sbjct: 109 PFSIDG-SGQLRATGLLSQER---YDVRVLASDGGTPQLSSALELTVLLMELQ-KEPACG 163

Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642
              Y   + E +   + + QV A     G  G++ Y L P D +   F I+  SG +   
Sbjct: 164 ASDYRVEVREGSPPLSRLLQVRAQPPGAG-EGQLIYRLRP-DADAVGFSIEADSGWLYVR 221

Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
            ALDRES   + L AV    G   +++T  V +++ D ND+ P    +      +EN P 
Sbjct: 222 GALDRESREAYVL-AVLASAGPGTRTATCTVRVRVTDENDNSPRLSEERFFLSATENRPP 280

Query: 703 GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762
           G T+G + A D D GPN  V Y +   +  + F +    G    EL T   LD E  +  
Sbjct: 281 GETVGRVSATDRDAGPNGRVSYRLPPLE--SDFHINPHTG----ELSTRRVLDREL-QAT 333

Query: 763 YELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792
           Y+L++ A    +PP      V I V D NDNAP
Sbjct: 334 YQLLVIAQDGGAPPRSVTGTVHITVLDENDNAP 366



 Score =  119 bits (287), Expect = 1e-24
 Identities = 110/355 (30%), Positives = 171/355 (48%), Gaps = 26/355 (7%)

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS----DTTDVEISVVDVNDNEP 579
           F+++ QTG+I     LD E+   +   V+  +    SL         +E+ V D ND+ P
Sbjct: 519 FMVDGQTGSIFLVGELDFESQPRFSFRVSVEEVREASLGYVPPHVVHIEVEVQDRNDHSP 578

Query: 580 VFKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDR-EEGS-FVIDPAS 636
            F +   T  + EDA VG+SV    A+D D  G N ++ Y L  +D    GS F +D  +
Sbjct: 579 AFPEDPLTLVVPEDAHVGSSVFTFQASDHDGPGPNSQVRYSLLRQDPGSPGSTFRLDAET 638

Query: 637 GVIRTNKALDRESVATHDLKAVAIDGG---TPPQSSTVIVHIKIEDINDSPPVFESDCLT 693
           GV+   +ALDRE V+++ L   A D     +  +S++V   + I D ND  P F +  L 
Sbjct: 639 GVLYVAQALDREEVSSYLLVVEASDQAVNVSQQRSTSVTARVFISDRNDHAPQFITP-LV 697

Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753
            ++ E+ P+G+T   + A DPD G N  V Y + GG+D   F L    G+    L  +  
Sbjct: 698 VWLPEDLPVGSTAIYMVAQDPDLGDNGKVGYQLVGGNDEGKFQLHPSSGA----LTVVRT 753

Query: 754 LDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV 810
           LD E+  + Y L + A    SP L +   + + + DVND AP  +  Q      ++  PV
Sbjct: 754 LDRETT-EGYNLTVVAMDHGSPRLSSTQTLSVSLLDVNDEAPSFEKPQ-YDAQVQENQPV 811

Query: 811 G-PFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKL 862
           G    RV A D D+  + ++ Y  +SG+      L+  TG +T    L+    +L
Sbjct: 812 GTTVLRVVALDRDLGQSGRVTYGGVSGDE---FALDPETGVLTTKVPLDREAKEL 863



 Score = 79.0 bits (186), Expect = 2e-12
 Identities = 57/186 (30%), Positives = 84/186 (45%), Gaps = 26/186 (13%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ V D ND+SP    +++  S  E    G TV  + ATD+D G N  V Y +  + +D 
Sbjct: 252 RVRVTDENDNSPRLSEERFFLSATENRPPGETVGRVSATDRDAGPNGRVSYRLPPLESD- 310

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                               F I+  +G L TR  LDRE  A Y +LV A D  +P    
Sbjct: 311 --------------------FHINPHTGELSTRRVLDRELQATYQLLVIAQDGGAPPR-- 348

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKT--YTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
            S T T+H+ ++D+NDN P F        +S+           IA ++A D D G N  +
Sbjct: 349 -SVTGTVHITVLDENDNAPTFLHPNAGKEISLQVMEGKKSGMFIASLQAKDPDEGENGTV 407

Query: 188 RYAIIG 193
            Y++ G
Sbjct: 408 TYSLAG 413



 Score = 41.9 bits (94), Expect = 0.25
 Identities = 27/87 (31%), Positives = 34/87 (39%), Gaps = 1/87 (1%)

Query: 334  LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTAT-D 392
            + V ATD G+PP S+TA               F     E+ L E+ P G+ V T TA   
Sbjct: 916  VFVQATDLGEPPLSSTAVLVVHLREEAPQGPRFPQEAIEISLPENSPEGSVVGTATAAHT 975

Query: 393  ADEDNRLHYEITGGNTRGRFSITSQNG 419
                 R+ Y    GN  G   I    G
Sbjct: 976  GGSTGRISYSFLSGNENGALRIHPTTG 1002



 Score = 41.9 bits (94), Expect = 0.25
 Identities = 22/85 (25%), Positives = 39/85 (45%), Gaps = 1/85 (1%)

Query: 659  AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
            A D G PP SST ++ + + +     P F  + +   + ENSP G+ +G   A     G 
Sbjct: 920  ATDLGEPPLSSTAVLVVHLREEAPQGPRFPQEAIEISLPENSPEGSVVGTATAAHTG-GS 978

Query: 719  NAVVHYSIKGGDDSNSFSLETRQGS 743
               + YS   G+++ +  +    G+
Sbjct: 979  TGRISYSFLSGNENGALRIHPTTGT 1003



 Score = 38.7 bits (86), Expect = 2.3
 Identities = 24/65 (36%), Positives = 35/65 (53%), Gaps = 6/65 (9%)

Query: 2   SVPFCIHQQINVLDCNDHSPVF----EMQQYEASVREGASSGTTVLTLKATDQDIGKNAE 57
           SV   +H  I VLD ND++P F      ++    V EG  SG  + +L+A D D G+N  
Sbjct: 349 SVTGTVH--ITVLDENDNAPTFLHPNAGKEISLQVMEGKKSGMFIASLQAKDPDEGENGT 406

Query: 58  VEYTI 62
           V Y++
Sbjct: 407 VTYSL 411



 Score = 38.7 bits (86), Expect = 2.3
 Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 5/98 (5%)

Query: 227  IRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE 286
            ++A D G P  S+T  L++++R+     PRF     + S+ EN P G S+V         
Sbjct: 918  VQATDLGEPPLSSTAVLVVHLREEAPQGPRFPQEAIEISLPENSPEG-SVVGTATAAHTG 976

Query: 287  GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
            G    ++Y+      +GN +  + I P +G    +G L
Sbjct: 977  GSTGRISYSF----LSGNENGALRIHPTTGTWGNTGTL 1010


>UniRef50_UPI0000660D80 Cluster: Homolog of Brachydanio rerio
           "Protocadherin1-alpha-av15-vCP.; n=1; Takifugu
           rubripes|Rep: Homolog of Brachydanio rerio
           "Protocadherin1-alpha-av15-vCP. - Takifugu rubripes
          Length = 1420

 Score =  321 bits (789), Expect = 2e-85
 Identities = 261/894 (29%), Positives = 415/894 (46%), Gaps = 79/894 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + + D NDHSP F   +    + E  S GT      A D D G N+   Y         L
Sbjct: 3   VEITDVNDHSPSFPETEQRFEMAEHTSPGTRFELHAARDPDTGLNSIRTYI--------L 54

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           +  D            +  F        L+ + SLDREK  +++++V A D   P   + 
Sbjct: 55  SANDHFGIEMSQSDEEKTPF--------LVLKQSLDREKSNKHSLVVTAVDGGKP---QR 103

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           S T  + + ++D+NDN P+F + TY + + E++ V     + K+ A D D GAN  I Y+
Sbjct: 104 SGTLNVSIIVLDNNDNIPRFDKDTYQIEISENVPV--GRTVTKVSAIDQDEGANGEIEYS 161

Query: 191 I---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
           +   +  N    F ++ L+G++ L   LD+E+  +Y+L I A D G+P   +  ++++ +
Sbjct: 162 LSKTLVRNVYDIFELNPLNGEIRLKGMLDFEESETYKLDIEASDKGTPPFRSRCRVIVKV 221

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            DV  +  R   S    +V E+   G  I  +   D D GVN ++   +T        D+
Sbjct: 222 IDVKSSRNR---SDITNTVPEDSKPGTVISLISVSDKDSGVNGKIISRITS-------DV 271

Query: 308 PITIDP----RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
           P  + P     +  + T   LDRE  + Y++++ A D G+PP S   +            
Sbjct: 272 PFELKPSYKENTYSIVTKAFLDREMTSHYEIIIQAVDCGEPPLSTVRSIQVQVSDINDNS 331

Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRF-SITSQNGR 420
             F+    +  L E+   G  + +++ATD D  E+  + Y I   N    F ++ S+NG+
Sbjct: 332 PRFIQNPLQFYLVENNVAGASIFSVSATDNDVSENAVISYSIARLNDVTSFLNVNSENGQ 391

Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYAPVF---ENAPYT 475
             I+  +  DF+  + +   V A+DSG  S ++ V +N  I D N+ APV     ++  +
Sbjct: 392 --ISALKSFDFETLKTFQFQVVASDSGSPSLSSNVTVNVFILDQNDNAPVILYPVSSNGS 449

Query: 476 ASVFEDAP----IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
           A   E+ P     G  V  V A D+D+G N  + +SL  ++S+ ++   D++        
Sbjct: 450 AEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSL-QQVSDHSLFGEDRKVPF----- 503

Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
            +   K LDRET S + L +TA DGG P+ S   D+ I V+DVNDN PVF ++LY++ I 
Sbjct: 504 -LVLQKQLDRETASSHKLQLTALDGGKPAKSGAIDIIIDVLDVNDNSPVFAKELYSSTIK 562

Query: 592 EDALVGTSVSQVGATDADVGLNGRIHY----ELDPKDREEGSFVIDPASGVIRTNKALDR 647
           E+  +GT V Q+ ATD D G NG I Y    E+D K      F ID  +G IR    +D 
Sbjct: 563 ENVPIGTVVIQINATDLDEGANGEIIYMFGKEMDSK--LMNVFDIDTNTGEIRVIGKIDF 620

Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
           E   + +L   A D    P ++   V I + DIND+ P  E    +  I E+S +GTT+ 
Sbjct: 621 EESRSFELDIQASDKAQAPLTTDKSVMISVIDINDNAPEIEVTSFSSSIKEDSKLGTTVA 680

Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
            I   D D G N  V  S+K   + + F+L     ++   +VT   LD E    KY+L I
Sbjct: 681 LISVSDLDSGINGKVICSLK---EDSPFNLSPSLQNNMYAVVTRSQLDREIV-SKYDLTI 736

Query: 768 RA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVT 824
            A     P    +  + ++V+DVNDN+P        F   ++  P      V A D D  
Sbjct: 737 VAKDTGEPTFLTEKTISLIVSDVNDNSPKFLSSSYGFYVTENNSPGASVFSVKASDCDEN 796

Query: 825 DK--LQY-----RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
           +   + Y     R L  N A+ + +N  TG +      +    K    +V  +D
Sbjct: 797 NNAMITYHIRRERTLDANFASFLNINSETGDIFALKSFDFETLKTFQFQVVASD 850



 Score =  316 bits (777), Expect = 4e-84
 Identities = 235/810 (29%), Positives = 389/810 (48%), Gaps = 63/810 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I+V+D ND++P  E+  + +S++E +  GTTV  +  +D D G N +V  +++  +   L
Sbjct: 648  ISVIDINDNAPEIEVTSFSSSIKEDSKLGTTVALISVSDLDSGINGKVICSLKEDSPFNL 707

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +P                   +     A++TR+ LDRE V++Y + + A D   P     
Sbjct: 708  SPS------------------LQNNMYAVVTRSQLDREIVSKYDLTIVAKDTGEPT---F 746

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             +  TI + + D NDN P+F   +Y   V E+ S      +  +KA+D D   N+ I Y 
Sbjct: 747  LTEKTISLIVSDVNDNSPKFLSSSYGFYVTENNS--PGASVFSVKASDCDENNNAMITYH 804

Query: 191  I-----IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
            I     +  N     +I+S +GD+  +K+ D+E +++++  + A D GSPS S+   + +
Sbjct: 805  IRRERTLDANFASFLNINSETGDIFALKSFDFETLKTFQFQVVASDSGSPSLSSNVTVNV 864

Query: 246  NIRDVNDNAPRFYTSLFQ-------ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
             I D NDNAP     +         E +  NV  G+ + +V+AYDAD G N  L +++  
Sbjct: 865  FILDQNDNAPVILYPVSSNGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQQ 924

Query: 299  KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358
                 +  L   +D  +G + T        +A+++L++   D G+   SATAT       
Sbjct: 925  ---VSDHSL-FGLDRYTGQIRTLRSFTETDEAEHKLVILVKDNGNVSLSATATVMVKLVE 980

Query: 359  XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITS 416
                       Q   +  ED   G       A DAD    +  HY+++  N   R  +  
Sbjct: 981  PKEAFAA-SDLQSSAKDDEDMLAGARFQLKGAQDADSGRFSVQHYKLSQ-NDHFRLEVKD 1038

Query: 417  QNGRG---LITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFEN 471
            +   G   ++ V + LD +    + L ++A D G   +S    + IN+ D N+ APVF  
Sbjct: 1039 RGKDGKIPILVVQKSLDRETAGSHSLVLTALDGGKPPKSGEMNILINVLDINDNAPVFSK 1098

Query: 472  APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
              Y+  + E+  IGTTV+ V+ATD+D G N ++ YS S+ ++   +      F IN  TG
Sbjct: 1099 DVYSVMLHENTLIGTTVIQVNATDADDGPNGEVVYSFSNSMNQNVL----DLFDINEITG 1154

Query: 532  AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
             IT    +D E    Y + V A D G   L     V I + DVNDN P  +   +++ I 
Sbjct: 1155 EITVKGPIDYEENERYEIEVEASDKGFVPLKTEKTVIIDITDVNDNAPEIEVTSFSSFIP 1214

Query: 592  EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG----VIRTNKALDR 647
            ED+  GT+V+ +   D D G+NG++   +      +  F + P+       + T  ALDR
Sbjct: 1215 EDSRPGTTVAHISVNDLDSGINGKVICTIS----NDSPFALTPSLKDKMFSLVTKSALDR 1270

Query: 648  ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
            E    +DL   A D G    SS   + + + D+ND+ P F     TFYISE +  GT++ 
Sbjct: 1271 EQRDKYDLTITAKDAGQLSLSSEKTITVVVSDVNDNRPEFSLSPYTFYISEANQPGTSVF 1330

Query: 708  EIRAHDPDEGPNAVVHYSI-KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYEL 765
             ++A D D+  NA V Y I + G   N  S      S+  +++ +   D+E+ +  ++++
Sbjct: 1331 SVKAFDRDDNDNAHVSYHILRDGSPENKLSSFLSINSETGDILALKSFDFEAQKTFQFQV 1390

Query: 766  VIR-AASPPLWNDVRVEILVTDVNDNAPVM 794
            V   + SP L ++V V++ + D NDNAPV+
Sbjct: 1391 VASDSGSPSLSSNVTVKVFILDQNDNAPVI 1420



 Score =  289 bits (708), Expect = 1e-75
 Identities = 245/890 (27%), Positives = 397/890 (44%), Gaps = 60/890 (6%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            Q+ V D ND+SP F     +  + E   +G ++ ++ ATD D+ +NA + Y+I       
Sbjct: 321  QVQVSDINDNSPRFIQNPLQFYLVENNVAGASIFSVSATDNDVSENAVISYSIA-----R 375

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            LN              V     ++  +G +    S D E +  +   V A+D  SP    
Sbjct: 376  LND-------------VTSFLNVNSENGQISALKSFDFETLKTFQFQVVASDSGSP---S 419

Query: 130  LSSTATIHVNIIDDNDNYPQF----SEKTYTVSVDE-DISVTDNPVIAKIKATDADVGAN 184
            LSS  T++V I+D NDN P      S       V+E   +V    ++ K++A DAD+G N
Sbjct: 420  LSSNVTVNVFILDQNDNAPVILYPVSSNGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYN 479

Query: 185  SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
              + +++   +    F  D     + L K LD E   S++L + A DGG P++S    ++
Sbjct: 480  GWLLFSLQQVSDHSLFGEDRKVPFLVLQKQLDRETASSHKLQLTALDGGKPAKSGAIDII 539

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
            I++ DVNDN+P F   L+  ++ ENVPIG  ++++ A D DEG N E+ Y M  K+    
Sbjct: 540  IDVLDVNDNSPVFAKELYSSTIKENVPIGTVVIQINATDLDEGANGEIIY-MFGKEMDSK 598

Query: 305  VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
            +     ID  +G +   G++D E    ++L + A+D    P +   +             
Sbjct: 599  LMNVFDIDTNTGEIRVIGKIDFEESRSFELDIQASDKAQAPLTTDKSVMISVIDINDNAP 658

Query: 365  XFMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQNGRGLI 423
                  +   + ED   GT V  ++ +D D   N         ++    S + QN    +
Sbjct: 659  EIEVTSFSSSIKEDSKLGTTVALISVSDLDSGINGKVICSLKEDSPFNLSPSLQNNMYAV 718

Query: 424  TVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFED 481
                 LD +   +Y LT+ A D+G  +      + + ++D N+ +P F ++ Y   V E+
Sbjct: 719  VTRSQLDREIVSKYDLTIVAKDTGEPTFLTEKTISLIVSDVNDNSPKFLSSSYGFYVTEN 778

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
               G +V  V A+D D   NA ITY +  E + +  A+      IN +TG I   K  D 
Sbjct: 779  NSPGASVFSVKASDCDENNNAMITYHIRRERTLD--ANFASFLNINSETGDIFALKSFDF 836

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT-------ANIMEDA 594
            ET+  +   V A D G PSLS    V + ++D NDN PV    + +         I  + 
Sbjct: 837  ETLKTFQFQVVASDSGSPSLSSNVTVNVFILDQNDNAPVILYPVSSNGSAEGVEEIPRNV 896

Query: 595  LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654
              G  V++V A DAD+G NG + + L  +  +   F +D  +G IRT ++      A H 
Sbjct: 897  NAGHLVTKVRAYDADIGYNGWLLFSLQ-QVSDHSLFGLDRYTGQIRTLRSFTETDEAEHK 955

Query: 655  LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR-AHD 713
            L  +  D G    S+T  V +K+  +        SD  +    +   +     +++ A D
Sbjct: 956  LVILVKDNGNVSLSATATVMVKL--VEPKEAFAASDLQSSAKDDEDMLAGARFQLKGAQD 1013

Query: 714  PDEGPNAVVHYSIKGGDDSNSFSLETR-QGSDK--AELVTMVDLDYESPRKKYELVIRA- 769
             D G  +V HY +   D    F LE + +G D     LV    LD E+    + LV+ A 
Sbjct: 1014 ADSGRFSVQHYKLSQND---HFRLEVKDRGKDGKIPILVVQKSLDRET-AGSHSLVLTAL 1069

Query: 770  --ASPPLWNDVRVEILVTDVNDNAPVM-KDFQIIFNNYKDCFPVGPFGRVPAYDAD--VT 824
                PP   ++ + I V D+NDNAPV  KD   +  +           +V A DAD    
Sbjct: 1070 DGGKPPKSGEMNILINVLDINDNAPVFSKDVYSVMLHENTLIGTTVI-QVNATDADDGPN 1128

Query: 825  DKLQYRILSGNNANLILL---NETTGSMTLSPQLNTNVPKLATMEVSVTD 871
             ++ Y   +  N N++ L   NE TG +T+   ++    +   +EV  +D
Sbjct: 1129 GEVVYSFSNSMNQNVLDLFDINEITGEITVKGPIDYEENERYEIEVEASD 1178



 Score =  288 bits (706), Expect = 2e-75
 Identities = 224/809 (27%), Positives = 379/809 (46%), Gaps = 60/809 (7%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           ++  I VLD ND+ P F+   Y+  + E    G TV  + A DQD G N E+EY++    
Sbjct: 107 LNVSIIVLDNNDNIPRFDKDTYQIEISENVPVGRTVTKVSAIDQDEGANGEIEYSL---- 162

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
           + TL               V D+F ++  +G +  +  LD E+   Y + ++A+D+ +P 
Sbjct: 163 SKTL------------VRNVYDIFELNPLNGEIRLKGMLDFEESETYKLDIEASDKGTP- 209

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
                S   + V +ID   +  + S+ T TV  D         VI+ I  +D D G N  
Sbjct: 210 --PFRSRCRVIVKVIDVKSSRNR-SDITNTVPEDS----KPGTVISLISVSDKDSGVNGK 262

Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
           I  + I  +   +          S+V    LD E    Y ++I+A D G P  S    + 
Sbjct: 263 I-ISRITSDVPFELKPSYKENTYSIVTKAFLDREMTSHYEIIIQAVDCGEPPLSTVRSIQ 321

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           + + D+NDN+PRF  +  Q  + EN   G SI  V A D D   NA ++Y++       +
Sbjct: 322 VQVSDINDNSPRFIQNPLQFYLVENNVAGASIFSVSATDNDVSENAVISYSIA---RLND 378

Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
           V   + ++  +G +      D ET   +Q  V A+D G P  S+  T             
Sbjct: 379 VTSFLNVNSENGQISALKSFDFETLKTFQFQVVASDSGSPSLSSNVTVNVFILDQNDNAP 438

Query: 365 XFM-----PGQYE--VELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSIT 415
             +      G  E   E+  +   G  V  + A DAD   +  L + +   +    F   
Sbjct: 439 VILYPVSSNGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQQVSDHSLFG-- 496

Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAP 473
                  + + + LD +    + L ++A D G   +S    + I++ D N+ +PVF    
Sbjct: 497 EDRKVPFLVLQKQLDRETASSHKLQLTALDGGKPAKSGAIDIIIDVLDVNDNSPVFAKEL 556

Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
           Y++++ E+ PIGT V+ ++ATD D G N +I Y    E+ ++ +      F I+  TG I
Sbjct: 557 YSSTIKENVPIGTVVIQINATDLDEGANGEIIYMFGKEMDSKLM----NVFDIDTNTGEI 612

Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593
                +D E    + L + A D     L+    V ISV+D+NDN P  +   ++++I ED
Sbjct: 613 RVIGKIDFEESRSFELDIQASDKAQAPLTTDKSVMISVIDINDNAPEIEVTSFSSSIKED 672

Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA----SGVIRTNKALDRES 649
           + +GT+V+ +  +D D G+NG++   L    +E+  F + P+       + T   LDRE 
Sbjct: 673 SKLGTTVALISVSDLDSGINGKVICSL----KEDSPFNLSPSLQNNMYAVVTRSQLDREI 728

Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
           V+ +DL  VA D G P   +   + + + D+ND+ P F S    FY++EN+  G ++  +
Sbjct: 729 VSKYDLTIVAKDTGEPTFLTEKTISLIVSDVNDNSPKFLSSSYGFYVTENNSPGASVFSV 788

Query: 710 RAHDPDEGPNAVVHYSIKGGD--DSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELV 766
           +A D DE  NA++ Y I+     D+N F+      S+  ++  +   D+E+ +  ++++V
Sbjct: 789 KASDCDENNNAMITYHIRRERTLDAN-FASFLNINSETGDIFALKSFDFETLKTFQFQVV 847

Query: 767 IR-AASPPLWNDVRVEILVTDVNDNAPVM 794
              + SP L ++V V + + D NDNAPV+
Sbjct: 848 ASDSGSPSLSSNVTVNVFILDQNDNAPVI 876



 Score =  276 bits (677), Expect = 6e-72
 Identities = 205/675 (30%), Positives = 330/675 (48%), Gaps = 51/675 (7%)

Query: 98  ALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTV 157
           +++T+A LDRE  + Y ++++A D   P    LS+  +I V + D NDN P+F +     
Sbjct: 285 SIVTKAFLDREMTSHYEIIIQAVDCGEP---PLSTVRSIQVQVSDINDNSPRFIQNPLQF 341

Query: 158 SVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQF-SIDSLSGDVSLVKTLD 216
            + E+ +V    + + + ATD DV  N+ I Y+I   N    F +++S +G +S +K+ D
Sbjct: 342 YLVEN-NVAGASIFS-VSATDNDVSENAVISYSIARLNDVTSFLNVNSENGQISALKSFD 399

Query: 217 YEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ-------ESVSEN 269
           +E +++++  + A D GSPS S+   + + I D NDNAP     +         E +  N
Sbjct: 400 FETLKTFQFQVVASDSGSPSLSSNVTVNVFILDQNDNAPVILYPVSSNGSAEGVEEIPRN 459

Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTM---TDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326
           V  G+ + +V+AYDAD G N  L +++   +D    G        D +  ++    QLDR
Sbjct: 460 VNAGHLVTKVRAYDADIGYNGWLLFSLQQVSDHSLFGE-------DRKVPFLVLQKQLDR 512

Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386
           ET + ++L +TA DGG P +S                  F    Y   + E+ P GT V+
Sbjct: 513 ETASSHKLQLTALDGGKPAKSGAIDIIIDVLDVNDNSPVFAKELYSSTIKENVPIGTVVI 572

Query: 387 TLTATDADE--DNRLHY---EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441
            + ATD DE  +  + Y   +         F I +  G   I V   +DF++ R + L +
Sbjct: 573 QINATDLDEGANGEIIYMFGKEMDSKLMNVFDIDTNTGE--IRVIGKIDFEESRSFELDI 630

Query: 442 SATDSGGRSDTA--MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499
            A+D      T    V I++ D N+ AP  E   +++S+ ED+ +GTTV ++S +D D G
Sbjct: 631 QASDKAQAPLTTDKSVMISVIDINDNAPEIEVTSFSSSIKEDSKLGTTVALISVSDLDSG 690

Query: 500 INAQITYSLSSEIS-NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558
           IN ++  SL  +   N + +  +  +       A+ T   LDRE +S Y LT+ A+D G 
Sbjct: 691 INGKVICSLKEDSPFNLSPSLQNNMY-------AVVTRSQLDREIVSKYDLTIVAKDTGE 743

Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618
           P+      + + V DVNDN P F    Y   + E+   G SV  V A+D D   N  I Y
Sbjct: 744 PTFLTEKTISLIVSDVNDNSPKFLSSSYGFYVTENNSPGASVFSVKASDCDENNNAMITY 803

Query: 619 ELDPK---DREEGSFV-IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674
            +  +   D    SF+ I+  +G I   K+ D E++ T   + VA D G+P  SS V V+
Sbjct: 804 HIRRERTLDANFASFLNINSETGDIFALKSFDFETLKTFQFQVVASDSGSPSLSSNVTVN 863

Query: 675 IKIEDINDSPPVF----ESDCLTFYISE---NSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
           + I D ND+ PV      S+     + E   N   G  + ++RA+D D G N  + +S++
Sbjct: 864 VFILDQNDNAPVILYPVSSNGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQ 923

Query: 728 GGDDSNSFSLETRQG 742
              D + F L+   G
Sbjct: 924 QVSDHSLFGLDRYTG 938



 Score =  220 bits (537), Expect = 5e-55
 Identities = 162/579 (27%), Positives = 272/579 (46%), Gaps = 21/579 (3%)

Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
           +++ I DVND++P F  +  +  ++E+   G       A D D G+N+  TY ++  D+ 
Sbjct: 1   VVVEITDVNDHSPSFPETEQRFEMAEHTSPGTRFELHAARDPDTGLNSIRTYILSANDHF 60

Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
           G +++  + + ++ ++     LDRE   K+ L+VTA DGG P RS T             
Sbjct: 61  G-IEMSQSDEEKTPFLVLKQSLDREKSNKHSLVVTAVDGGKPQRSGTLNVSIIVLDNNDN 119

Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNG- 419
              F    Y++E++E+ P G  V  ++A D DE  +  + Y ++    R  + I   N  
Sbjct: 120 IPRFDKDTYQIEISENVPVGRTVTKVSAIDQDEGANGEIEYSLSKTLVRNVYDIFELNPL 179

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479
            G I +   LDF++   Y L + A+D G     +  ++ I    +       +  T +V 
Sbjct: 180 NGEIRLKGMLDFEESETYKLDIEASDKGTPPFRSRCRV-IVKVIDVKSSRNRSDITNTVP 238

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           ED+  GT + ++S +D D G+N +I   ++S++  E    + +       T +I T   L
Sbjct: 239 EDSKPGTVISLISVSDKDSGVNGKIISRITSDVPFELKPSYKEN------TYSIVTKAFL 292

Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
           DRE  S Y + + A D G P LS    +++ V D+NDN P F Q      ++E+ + G S
Sbjct: 293 DREMTSHYEIIIQAVDCGEPPLSTVRSIQVQVSDINDNSPRFIQNPLQFYLVENNVAGAS 352

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
           +  V ATD DV  N  I Y +   +       ++  +G I   K+ D E++ T   + VA
Sbjct: 353 IFSVSATDNDVSENAVISYSIARLNDVTSFLNVNSENGQISALKSFDFETLKTFQFQVVA 412

Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVF----ESDCLTFYISE---NSPIGTTIGEIRAH 712
            D G+P  SS V V++ I D ND+ PV      S+     + E   N   G  + ++RA+
Sbjct: 413 SDSGSPSLSSNVTVNVFILDQNDNAPVILYPVSSNGSAEGVEEIPRNVNAGHLVTKVRAY 472

Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP 772
           D D G N  + +S++   D + F  E R+      L   +D +  S  K     +    P
Sbjct: 473 DADIGYNGWLLFSLQQVSDHSLFG-EDRK-VPFLVLQKQLDRETASSHKLQLTALDGGKP 530

Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811
                + + I V DVNDN+PV    ++  +  K+  P+G
Sbjct: 531 AKSGAIDIIIDVLDVNDNSPVFAK-ELYSSTIKENVPIG 568


>UniRef50_A7RI52 Cluster: Predicted protein; n=1; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 4697

 Score =  318 bits (782), Expect = 1e-84
 Identities = 332/1239 (26%), Positives = 538/1239 (43%), Gaps = 135/1239 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V+D NDH+P F M+ YE  + E +  GT ++ + A D D G+   V Y+        L
Sbjct: 2516 VTVIDVNDHTPTFNMETYECRIFENSPVGTGIIRVHAEDLDTGR---VTYS--------L 2564

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +P                 F ID + G +      DRE+ +RY++   ATD  SP     
Sbjct: 2565 HPSRDYQK-----------FTIDTQRGTIRNAVVFDREEESRYSLTAIATDAGSPP---F 2610

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S+   + ++++D ND  P F +K    SV ED  +  +  + K    D+D+  ++++ + 
Sbjct: 2611 STQVFVKIDVLDANDQPPSFPDKNLQASVREDAPIGSS--VYKAVILDSDMVFDTSMHFF 2668

Query: 191  IIGGNTQMQFSI------DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
            I GGN + +F +       S  G V ++  LDYE  R ++L +   DG +   S+   L 
Sbjct: 2669 ISGGNEKHKFRVVTVTQQSSFYGLVEVIGRLDYETQREFKLRLTISDGKT---SDFGFLT 2725

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG-VNAELTYTMTDKDYTG 303
            I + D NDNAP F   +++ S+ E  P G S+V V A D D   V   +TY++   D  G
Sbjct: 2726 IKVTDANDNAPLFSKLVYEVSLREESPAGTSVVTVSAIDIDSPPVQEAITYSI---DKRG 2782

Query: 304  NVDLPITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
              +    I   +G +      LDRE    Y   V A+DG +  R+               
Sbjct: 2783 --EQYFRISSSTGEITCGASPLDREKLLYYFFTVYASDGKNQGRAEVMVTLVDINDQAP- 2839

Query: 363  XXXFMPGQ-YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG-- 419
               F P   Y   L E+   GT V  + A D D+ N       GGNT+  +S+   NG  
Sbjct: 2840 ---FFPNPPYYAALFENRAIGTNVTVMQAIDNDDPN------AGGNTKIIYSLEDNNGGY 2890

Query: 420  ------RGLITVAQPLDFK--QERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVF 469
                   GL+T  + +D +  QE  + +TV ATD G    S T ++Q+   D N++ P F
Sbjct: 2891 VTIDSSSGLVTSIKMVDREALQEDSFKVTVRATDQGQPALSGTTVLQVFFEDENDHKPKF 2950

Query: 470  ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
                Y ASV E    G  V  V ATD D G N  + Y +     NE  A     F I P+
Sbjct: 2951 VRQYYYASVSESTRTGVAVTRVEATDEDTGYNGMMNYFIVQ--GNEPYA-----FFIEPR 3003

Query: 530  TGAITTNKLLDRETMSGYLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFKQQLYT 587
            TG +  + +LD E+   Y L V   D G+P L   +   V +++ D N + P F Q+++ 
Sbjct: 3004 TGVVRVSGILDFESKKSYELIVMVSDMGMPQLLADNLAYVFVNITDDNTHPPRFAQKVHE 3063

Query: 588  ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI-----DPASGVIRTN 642
            A++ ED  +G SV  + ATD D       H  L     EE  F I     +  + +I   
Sbjct: 3064 ASVREDVPLGYSVLTIKATDIDTV--DSFHRFLISSGDEENMFTITESESEKMTAIITVR 3121

Query: 643  KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
              LDRE  + +++  V  D  T  QS   IV I + D ND+ P F+    + ++ EN   
Sbjct: 3122 GKLDRERKSFYNMIVVVND--TSGQSDECIVKITVTDANDNGPHFQPSYFSGFVRENIDS 3179

Query: 703  GTTIGEIRAHDPDEGPNA-VVHYSIKGGDDSNSFSL-ETRQGSDKAELVTMVDLDYESPR 760
               +  I A DPD   N     +++     S+ F + ++   S+ A++      D E   
Sbjct: 3180 EQFVTTISATDPDMPSNGPPFTFTLINTKQSSQFRIKDSTVTSNTAQVFAYGTFDREL-T 3238

Query: 761  KKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVP 817
              Y+L++ A+    P +WN   + + V DVN++ P+  +  II N     F  G  GR  
Sbjct: 3239 PFYKLLVNASDSGRPAMWNHTYIYVDVLDVNEHEPIDGNNTIIVNALDGAFAGGVIGRPY 3298

Query: 818  AYDADVTDKLQ-YRILSGNNANLILLNETTGSMTLSP--QLNTNVPKLATME-VSVTD-G 872
              D D    +  Y++ S +    + +N  TG++T SP   L   V K + +E V   D  
Sbjct: 3299 YQDDDYNGDINVYKMTSQSPGAYLDMNSATGAITASPGIPLGEYVVKASVIESVPRQDKA 3358

Query: 873  VNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDG-LAAIIPCPKENI 931
               ++   ++ VR ++ + +L S T+RL DM           + ++  LA I   P++++
Sbjct: 3359 PKTVETTTRVVVRNVSTQAVLASTTMRLTDMRKPGLFVQDYYYTVERLLAGIFGVPRDHV 3418

Query: 932  YIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLA- 990
             IF +Q +     ++ ++  + R     + V            +  ++   +T L  +  
Sbjct: 3419 VIFGIQQNQTTLPSV-DIQLAIRENQGFLSV----------DTISAKIMNKKTQLTSIGL 3467

Query: 991  TVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGF 1050
             V  +  D   C  +  L+   C TV +   AS F   D    +   P  S T    +  
Sbjct: 3468 NVDTVRIDK--CSGDRTLS-GVCTTVTE--PASTFRVVDGDYGQVPAPAESLTIVSMDVT 3522

Query: 1051 TGVNCETILTK-ASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCELRARS 1109
               + E+++ +  +C      + C +   C      G+LC+ C  +  +    C+   RS
Sbjct: 3523 HRASYESLIPEPKNC---SSSNPCLNNGICHDIFPSGVLCE-C--EPKFRGPYCQETTRS 3576

Query: 1110 FPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNE-----RHDFLALELVSSEA 1164
            F  +S++    +K       + +F T+ + GL+LY G   +       DFLA+ L S   
Sbjct: 3577 FKGNSYIWLKTMKAFPGNDFEFEFITKESDGLMLYQGPLTDLPAWVPRDFLAVMLTSGY- 3635

Query: 1165 GRGGGPGLRFSFSLGGG--KSEITVEGNVGDGSWHTVEI 1201
                   +  S SLG       +T    + DG WH ++I
Sbjct: 3636 -------VTVSISLGSTPVSLNMTRGPTLNDGEWHHLKI 3667



 Score =  307 bits (754), Expect = 3e-81
 Identities = 242/800 (30%), Positives = 381/800 (47%), Gaps = 58/800 (7%)

Query: 9    QQINVLDCND-HSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
            Q + V+D      P+FE   Y  SVRE A+ GTT+  ++A  Q+   N  + Y       
Sbjct: 2405 QTLVVIDVTTVEPPMFERHLYNISVRENAAVGTTIGQIRAVSQN---NRPIMYQ-----P 2456

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
               NP              ++   I+  +G+++T + LD E V  Y +   A + ++  S
Sbjct: 2457 LHENPN------------AKEEIGIEIDTGSIVTSSKLDYESVNNYELQFVAVETSTDKS 2504

Query: 128  DRLS-STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
            + L  ST  ++V +ID ND+ P F+ +TY   + E+  V     I ++ A D D G    
Sbjct: 2505 ETLLFSTCFVNVTVIDVNDHTPTFNMETYECRIFENSPVGTG--IIRVHAEDLDTGR--- 2559

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            + Y++       +F+ID+  G +      D E+   Y L   A D GSP  S    + I+
Sbjct: 2560 VTYSLHPSRDYQKFTIDTQRGTIRNAVVFDREEESRYSLTAIATDAGSPPFSTQVFVKID 2619

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            + D ND  P F     Q SV E+ PIG S+ +    D+D   +  + + ++  +      
Sbjct: 2620 VLDANDQPPSFPDKNLQASVREDAPIGSSVYKAVILDSDMVFDTSMHFFISGGNEKHKFR 2679

Query: 307  LPITIDPRS---GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
            + +T+  +S   G V   G+LD ETQ +++L +T +DG     S                
Sbjct: 2680 V-VTVTQQSSFYGLVEVIGRLDYETQREFKLRLTISDG---KTSDFGFLTIKVTDANDNA 2735

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGR--FSITSQNGRG 421
              F    YEV L E+ P GT VVT++A D D            + RG   F I+S  G  
Sbjct: 2736 PLFSKLVYEVSLREESPAGTSVVTVSAIDIDSPPVQEAITYSIDKRGEQYFRISSSTGE- 2794

Query: 422  LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
            +   A PLD ++   Y  TV A+D G     A V + + D N+ AP F N PY A++FE+
Sbjct: 2795 ITCGASPLDREKLLYYFFTVYASD-GKNQGRAEVMVTLVDINDQAPFFPNPPYYAALFEN 2853

Query: 482  APIGTTVLVVSATDSD---VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
              IGT V V+ A D+D    G N +I YSL          ++     I+  +G +T+ K+
Sbjct: 2854 RAIGTNVTVMQAIDNDDPNAGGNTKIIYSLED--------NNGGYVTIDSSSGLVTSIKM 2905

Query: 539  LDRETMS--GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
            +DRE +    + +TV A D G P+LS TT +++   D ND++P F +Q Y A++ E    
Sbjct: 2906 VDREALQEDSFKVTVRATDQGQPALSGTTVLQVFFEDENDHKPKFVRQYYYASVSESTRT 2965

Query: 597  GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
            G +V++V ATD D G NG ++Y +  +  E  +F I+P +GV+R +  LD ES  +++L 
Sbjct: 2966 GVAVTRVEATDEDTGYNGMMNYFI-VQGNEPYAFFIEPRTGVVRVSGILDFESKKSYELI 3024

Query: 657  AVAIDGGTPP--QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
             +  D G P     +   V + I D N  PP F        + E+ P+G ++  I+A D 
Sbjct: 3025 VMVSDMGMPQLLADNLAYVFVNITDDNTHPPRFAQKVHEASVREDVPLGYSVLTIKATDI 3084

Query: 715  DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK-YELVIRAASPP 773
            D   ++   + I  GD+ N F++ T   S+K   +  V    +  RK  Y +++      
Sbjct: 3085 DT-VDSFHRFLISSGDEENMFTI-TESESEKMTAIITVRGKLDRERKSFYNMIVVVNDTS 3142

Query: 774  LWND-VRVEILVTDVNDNAP 792
              +D   V+I VTD NDN P
Sbjct: 3143 GQSDECIVKITVTDANDNGP 3162



 Score =  264 bits (647), Expect = 2e-68
 Identities = 231/812 (28%), Positives = 384/812 (47%), Gaps = 66/812 (8%)

Query: 87   QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146
            Q+ F+ID  +G + +   L       Y + VKATD  SP    + S  ++ V++I     
Sbjct: 907  QNRFQIDSSTGTITSTNLLAANN--EYKLTVKATDTGSPP---MESQVSVTVSVITPITT 961

Query: 147  YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206
              +F+E  Y  ++ E + V  N V+ ++ AT       +AI Y+I+GGN    F ID  +
Sbjct: 962  PVKFAEANYAKTIQESL-VIGNSVL-QVTATGP-----AAITYSIVGGNKNDAFRIDRTT 1014

Query: 207  GDVSLVKTLDYEQVRSYRLVIRAQ-DGGSPSRSNTTQLLINIRDVNDNAPRF--YTSLFQ 263
            G +++ K LDYE ++SY L +RA  +  +P  +    + I + DVNDN+P F  Y++   
Sbjct: 1015 GQIAVNKPLDYEVLQSYVLNVRATCETYTPKIAAEVAVAITLTDVNDNSPVFLLYSNPTT 1074

Query: 264  ESVSENVP----------IGYSIV--RVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311
             +V+   P            Y ++  +  A DAD      + Y++       + DLP ++
Sbjct: 1075 VTVNSYTPEQTVVFKARRFTYYVIYEKALAVDADSESFGTVRYSINSASSNPSSDLPFSL 1134

Query: 312  DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371
            D  SG + T+  +    +A+Y + + ATDGG     +T T              F   +Y
Sbjct: 1135 DASSGQMKTTRVIKYSDRAEYTVALVATDGGG---KSTTTSLVIKVFNINEPPKFPQPKY 1191

Query: 372  EVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431
            E  + E++  GT +  +TAT AD +  L Y IT GN    F +   N +G+I++A+ LD 
Sbjct: 1192 EFSVPENKQVGTEIGAITATYADPNTLLKYSITRGNIDDTFCV---NSKGVISLAKALD- 1247

Query: 432  KQERRYVLTVSATDSGGRSD-TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
              E +   T+ A  S G S+ T +VQI + D N+  P+ E   Y   V ED   GT ++ 
Sbjct: 1248 -SETKASFTLDAMVSHGTSNHTTVVQITVNDINDNWPIMEPV-YNVEVREDQAPGTELVK 1305

Query: 491  VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550
            V ATD D G+   ITY++   I  + +      F +N  TG IT  + LD E ++ ++L 
Sbjct: 1306 VVATDLDGGVGGTITYTI---IQTQDIG-SSSLFAVNASTGVITLVQKLDAEDINKHVLY 1361

Query: 551  VTARDGG-VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
            V A DGG  P  +  T V + V DVND+ P F    Y A++  +  V   V QV ATDAD
Sbjct: 1362 VKAEDGGPTPKYAAITKVVVLVGDVNDHAPRFSSSQYLASVPYEFPVNFHVFQVIATDAD 1421

Query: 610  VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ-- 667
             G N  + Y +     E+G F I+  +G++   + L   +   H L   A D G P +  
Sbjct: 1422 SGSNAELTYAI-TGGNEDGIFKINSENGLVSLARPLASSAKIKHKLSLKATDNGVPRRIG 1480

Query: 668  SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
            +ST+IV + + D+    P F    L   + E    G  +  ++        + ++ Y I 
Sbjct: 1481 TSTIIVFVILADL---LPKFPVSPLIVNVKEGVLPGGRVTTVKMTS-----SRLMTYRIL 1532

Query: 728  GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND-VRVEILVTD 786
             G+D   F +++  G    +L+ + +LDYE  R  + + I+        D V + + + D
Sbjct: 1533 EGNDEGYFRMDSLSG----DLLALKELDYEDVR-TFTMRIKGQDTDGNADVVTLVVNLED 1587

Query: 787  VNDNAPVMK---DFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLILL 842
            VND +PV       +++    +     G P  ++  YD D  D+L +  LS     +  +
Sbjct: 1588 VNDCSPVFAGEVGGEVMLRVEEPFLVAGVPVVKLDVYDKDAGDRLTFE-LSDEGERIFTI 1646

Query: 843  NETTGSMTLSPQLNTNVPKLATMEVSVTDGVN 874
            ++  G +  +  +N ++ +  +  V+V D  +
Sbjct: 1647 DD-EGQLIPTRSVN-DITEPLSFTVTVRDSAS 1676



 Score =  253 bits (620), Expect = 5e-65
 Identities = 250/910 (27%), Positives = 406/910 (44%), Gaps = 88/910 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I++ + ND+ P F    +  +V E    GT++L + ATD D  K+               
Sbjct: 1986 IHLKNINDNYPRFTKSLFTTAVNEDVPVGTSILQVTATDCDCSKSC------------LC 2033

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             P +             D+F I   +G +    SLD E  +   ++VK  D+     + +
Sbjct: 2034 APGELTYSIDNT-----DMFAISPDTGVISPAVSLDYEMSSWVVLVVKVEDKGGS-PNIM 2087

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             S A I   ++  NDN P F++  Y   + E   V +   +A + ATD D      I Y 
Sbjct: 2088 QSYANI--TLLPVNDNSPVFAQSNYAFQISETAEVGNE--LAFVTATDRD---GDPITYT 2140

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I G +    + ID  SG ++L +      V  Y   ++A DG   +   TT +L++I D 
Sbjct: 2141 IEGDSGP--YIIDPSSGIITLSREAPVN-VWEYNFKVKATDGIFTA---TTDVLLDIIDQ 2194

Query: 251  NDNAPRFY----TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            N++ P+F     +S   + ++EN+P G  +++VQA D D G+N E+ Y +      G  D
Sbjct: 2195 NNHKPQFTNCGESSRTVKEIAENLPSGQVLMQVQATDEDRGLNGEVEYELV----IGFTD 2250

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX- 365
               +ID  +G + T   LDRE  +K  ++V A DGG                        
Sbjct: 2251 F--SIDNTTGVIKTRYPLDRERTSKQYIVVRAKDGGHRRNELFRNINYCLIIVSVVDAND 2308

Query: 366  ----FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421
                F   +Y   + +  P G  +V + A D D  +    E T      +F+I  +   G
Sbjct: 2309 NYPLFHIHRYVSSVYQKAPVGHSLVRVKAIDLDTGSNAKVEYTFVEPSDKFAI--EKTTG 2366

Query: 422  LITVAQPLD---------FKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENA 472
            ++TV   L           +      +TVS  +   R    +V I++T      P+FE  
Sbjct: 2367 IVTVKTDLSSFTGFVTLQVQSSNPVPITVSVGEDD-RDRQTLVVIDVTTVE--PPMFERH 2423

Query: 473  PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
             Y  SV E+A +GTT+  + A   +   N  I Y    E  N       ++  I   TG+
Sbjct: 2424 LYNISVRENAAVGTTIGQIRAVSQN---NRPIMYQPLHENPNAK-----EEIGIEIDTGS 2475

Query: 533  ITTNKLLDRETMSGYLLTV----TARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588
            I T+  LD E+++ Y L      T+ D     L  T  V ++V+DVND+ P F  + Y  
Sbjct: 2476 IVTSSKLDYESVNNYELQFVAVETSTDKSETLLFSTCFVNVTVIDVNDHTPTFNMETYEC 2535

Query: 589  NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648
             I E++ VGT + +V A D D G   R+ Y L P  R+   F ID   G IR     DRE
Sbjct: 2536 RIFENSPVGTGIIRVHAEDLDTG---RVTYSLHPS-RDYQKFTIDTQRGTIRNAVVFDRE 2591

Query: 649  SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
              + + L A+A D G+PP S+ V V I + D ND PP F    L   + E++PIG+++ +
Sbjct: 2592 EESRYSLTAIATDAGSPPFSTQVFVKIDVLDANDQPPSFPDKNLQASVREDAPIGSSVYK 2651

Query: 709  IRAHDPDEGPNAVVHYSIKGGDDSNSFSLET-RQGSDKAELVTMVD-LDYESPRKKYELV 766
                D D   +  +H+ I GG++ + F + T  Q S    LV ++  LDYE+ R +++L 
Sbjct: 2652 AVILDSDMVFDTSMHFFISGGNEKHKFRVVTVTQQSSFYGLVEVIGRLDYETQR-EFKLR 2710

Query: 767  IRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVG-PFGRVPAYDAD-- 822
            +  +     +   + I VTD NDNAP+    ++++  + ++  P G     V A D D  
Sbjct: 2711 LTISDGKTSDFGFLTIKVTDANDNAPLFS--KLVYEVSLREESPAGTSVVTVSAIDIDSP 2768

Query: 823  -VTDKLQYRILSGNNANLILLNETTGSMTL-SPQLNTNVPKLATMEVSVTDGVNEIKAMM 880
             V + + Y I          ++ +TG +T  +  L+          V  +DG N+ +A +
Sbjct: 2769 PVQEAITYSI-DKRGEQYFRISSSTGEITCGASPLDREKLLYYFFTVYASDGKNQGRAEV 2827

Query: 881  QLSVRLITEE 890
             +++  I ++
Sbjct: 2828 MVTLVDINDQ 2837



 Score =  246 bits (602), Expect = 7e-63
 Identities = 235/873 (26%), Positives = 385/873 (44%), Gaps = 91/873 (10%)

Query: 8    HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
            +  I +L  ND+SPVF    Y   + E A  G  +  + ATD+D      + YTIE    
Sbjct: 2090 YANITLLPVNDNSPVFAQSNYAFQISETAEVGNELAFVTATDRD---GDPITYTIE---G 2143

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
            D+  P                 + ID  SG ++T +      V  Y   VKATD      
Sbjct: 2144 DS-GP-----------------YIIDPSSG-IITLSREAPVNVWEYNFKVKATDGI---- 2180

Query: 128  DRLSSTATIHVNIIDDNDNYPQFS---EKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184
               ++T  + ++IID N++ PQF+   E + TV    + ++    V+ +++ATD D G N
Sbjct: 2181 --FTATTDVLLDIIDQNNHKPQFTNCGESSRTVKEIAE-NLPSGQVLMQVQATDEDRGLN 2237

Query: 185  SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS-----N 239
              + Y ++ G T   FSID+ +G +     LD E+     +V+RA+DGG          N
Sbjct: 2238 GEVEYELVIGFTD--FSIDNTTGVIKTRYPLDRERTSKQYIVVRAKDGGHRRNELFRNIN 2295

Query: 240  TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
               +++++ D NDN P F+   +  SV +  P+G+S+VRV+A D D G NA++ YT  + 
Sbjct: 2296 YCLIIVSVVDANDNYPLFHIHRYVSSVYQKAPVGHSLVRVKAIDLDTGSNAKVEYTFVEP 2355

Query: 300  DYTGNVDLPI-TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358
                 ++     +  ++     +G +  + Q+   + +T + G D     T         
Sbjct: 2356 SDKFAIEKTTGIVTVKTDLSSFTGFVTLQVQSSNPVPITVSVGEDDRDRQTLV---VIDV 2412

Query: 359  XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR-LHYEITGGNTRGRFSITSQ 417
                   F    Y + + E+   GT +  + A    ++NR + Y+    N   +  I  +
Sbjct: 2413 TTVEPPMFERHLYNISVRENAAVGTTIGQIRA--VSQNNRPIMYQPLHENPNAKEEIGIE 2470

Query: 418  NGRGLITVAQPLDFKQERRYVLT-VSATDSGGRSDTAM-----VQINITDANNYAPVFEN 471
               G I  +  LD++    Y L  V+   S  +S+T +     V + + D N++ P F  
Sbjct: 2471 IDTGSIVTSSKLDYESVNNYELQFVAVETSTDKSETLLFSTCFVNVTVIDVNDHTPTFNM 2530

Query: 472  APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
              Y   +FE++P+GT ++ V A D D G   ++TYSL         +   Q+F I+ Q G
Sbjct: 2531 ETYECRIFENSPVGTGIIRVHAEDLDTG---RVTYSLHP-------SRDYQKFTIDTQRG 2580

Query: 532  AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
             I    + DRE  S Y LT  A D G P  S    V+I V+D ND  P F  +   A++ 
Sbjct: 2581 TIRNAVVFDREEESRYSLTAIATDAGSPPFSTQVFVKIDVLDANDQPPSFPDKNLQASVR 2640

Query: 592  EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS-----GVIRTNKALD 646
            EDA +G+SV +    D+D+  +  +H+ +   + +    V+         G++     LD
Sbjct: 2641 EDAPIGSSVYKAVILDSDMVFDTSMHFFISGGNEKHKFRVVTVTQQSSFYGLVEVIGRLD 2700

Query: 647  RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706
             E+     L+    DG T   S    + IK+ D ND+ P+F        + E SP GT++
Sbjct: 2701 YETQREFKLRLTISDGKT---SDFGFLTIKVTDANDNAPLFSKLVYEVSLREESPAGTSV 2757

Query: 707  GEIRAHDPDEGP-NAVVHYSI-KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764
              + A D D  P    + YSI K G+     S  T + +  A  +    L Y      Y 
Sbjct: 2758 VTVSAIDIDSPPVQEAITYSIDKRGEQYFRISSSTGEITCGASPLDREKLLY------YF 2811

Query: 765  LVIRAASPPLWNDVRVEILVT--DVNDNAPVMKD---FQIIFNNYKDCFPVGPFGRVPAY 819
              + A+     N  R E++VT  D+ND AP   +   +  +F N      V     +   
Sbjct: 2812 FTVYASDGK--NQGRAEVMVTLVDINDQAPFFPNPPYYAALFENRAIGTNVTVMQAIDND 2869

Query: 820  D--ADVTDKLQYRILSGNNANLILLNETTGSMT 850
            D  A    K+ Y  L  NN   + ++ ++G +T
Sbjct: 2870 DPNAGGNTKIIYS-LEDNNGGYVTIDSSSGLVT 2901



 Score =  217 bits (531), Expect = 3e-54
 Identities = 230/855 (26%), Positives = 371/855 (43%), Gaps = 103/855 (12%)

Query: 11   INVLDCNDHSPVFE-MQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            I+V+D ND+ P F  + +    + + + +G+ VL+L A D D  +N EV + I       
Sbjct: 1779 ISVIDVNDNVPRFTGITRIYKRINKNSLNGSPVLSLNALDLDYERNGEVGFQIV------ 1832

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
              P D               F I+     + T  +L++E    Y   V A D   P  + 
Sbjct: 1833 --PRDGP-------------FGINPVDEMIETTGNLNKES---YEFDVYAFDYGIPRLNS 1874

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             +    +HV  +             Y     E  +     +I  +KA      + + I Y
Sbjct: 1875 TTIPMVVHVAEVPPIFEVLDNDHNMYRFETAE--TSHGGELIGTVKAVSY---SKALIAY 1929

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYE-QVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
             I  GN +  F I +L+G++     ++YE     Y L + A +           ++I+++
Sbjct: 1930 EITSGNVRNSFKIGTLTGEIRHNNFMNYEIHENVYNLTVTASELIPRGHQTEIPVIIHLK 1989

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN-----AELTYTMTDKDYTG 303
            ++NDN PRF  SLF  +V+E+VP+G SI++V A D D   +      ELTY++ + D   
Sbjct: 1990 NINDNYPRFTKSLFTTAVNEDVPVGTSILQVTATDCDCSKSCLCAPGELTYSIDNTDM-- 2047

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
                   I P +G +  +  LD E  +   L+V   D G  P    +             
Sbjct: 2048 -----FAISPDTGVISPAVSLDYEMSSWVVLVVKVEDKGGSPNIMQSYANITLLPVNDNS 2102

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423
              F    Y  +++E    G  +  +TATD D D  + Y I G +  G + I   +G   +
Sbjct: 2103 PVFAQSNYAFQISETAEVGNELAFVTATDRDGD-PITYTIEGDS--GPYIIDPSSGIITL 2159

Query: 424  TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA----SVF 479
            +   P++  +   Y   V ATD G  + T  V ++I D NN+ P F N   ++     + 
Sbjct: 2160 SREAPVNVWE---YNFKVKATD-GIFTATTDVLLDIIDQNNHKPQFTNCGESSRTVKEIA 2215

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
            E+ P G  ++ V ATD D G+N ++ Y L        +   D  F I+  TG I T   L
Sbjct: 2216 ENLPSGQVLMQVQATDEDRGLNGEVEYEL-------VIGFTD--FSIDNTTGVIKTRYPL 2266

Query: 540  DRETMSGYLLTVTARDGGVPSLSDTTDVE-----ISVVDVNDNEPVFKQQLYTANIMEDA 594
            DRE  S   + V A+DGG        ++      +SVVD NDN P+F    Y +++ + A
Sbjct: 2267 DRERTSKQYIVVRAKDGGHRRNELFRNINYCLIIVSVVDANDNYPLFHIHRYVSSVYQKA 2326

Query: 595  LVGTSVSQVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGVIRTNKALDRES---- 649
             VG S+ +V A D D G N ++ Y  ++P D+    F I+  +G++     L   +    
Sbjct: 2327 PVGHSLVRVKAIDLDTGSNAKVEYTFVEPSDK----FAIEKTTGIVTVKTDLSSFTGFVT 2382

Query: 650  --VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
              V + +   + +  G   +    +V I +  +   PP+FE       + EN+ +GTTIG
Sbjct: 2383 LQVQSSNPVPITVSVGEDDRDRQTLVVIDVTTV--EPPMFERHLYNISVRENAAVGTTIG 2440

Query: 708  EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
            +IRA   +  P  +++  +    ++     E     D   +VT   LDYES    YEL  
Sbjct: 2441 QIRAVSQNNRP--IMYQPLHENPNAKE---EIGIEIDTGSIVTSSKLDYESV-NNYELQF 2494

Query: 768  RAASPP-------LWNDVRVEILVTDVNDNAPV--MKDFQI-IFNNYKDCFPVGP-FGRV 816
             A           L++   V + V DVND+ P   M+ ++  IF N     PVG    RV
Sbjct: 2495 VAVETSTDKSETLLFSTCFVNVTVIDVNDHTPTFNMETYECRIFEN----SPVGTGIIRV 2550

Query: 817  PAYDADVTDKLQYRI 831
             A D D T ++ Y +
Sbjct: 2551 HAEDLD-TGRVTYSL 2564



 Score =  208 bits (508), Expect = 2e-51
 Identities = 197/734 (26%), Positives = 318/734 (43%), Gaps = 57/734 (7%)

Query: 2    SVPFC--IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVE 59
            S PF   +  +I+VLD ND  P F  +  +ASVRE A  G++V      D D+  +  + 
Sbjct: 2607 SPPFSTQVFVKIDVLDANDQPPSFPDKNLQASVREDAPIGSSVYKAVILDSDMVFDTSMH 2666

Query: 60   YTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKA 119
            + I                       V  V +     G +     LD E    + + +  
Sbjct: 2667 FFI-------------SGGNEKHKFRVVTVTQQSSFYGLVEVIGRLDYETQREFKLRLTI 2713

Query: 120  TDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA 179
            +D       + S    + + + D NDN P FS+  Y VS+ E+ S     V+  + A D 
Sbjct: 2714 SD------GKTSDFGFLTIKVTDANDNAPLFSKLVYEVSLREE-SPAGTSVVT-VSAIDI 2765

Query: 180  D-VGANSAIRYAIIGGNTQMQFSIDSLSGDVSL-VKTLDYEQVRSYRLVIRAQDGGSPSR 237
            D      AI Y+ I    +  F I S +G+++     LD E++  Y   + A DG +  R
Sbjct: 2766 DSPPVQEAITYS-IDKRGEQYFRISSSTGEITCGASPLDREKLLYYFFTVYASDGKNQGR 2824

Query: 238  SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE---GVNAELTY 294
            +   ++++ + D+ND AP F    +  ++ EN  IG ++  +QA D D+   G N ++ Y
Sbjct: 2825 A---EVMVTLVDINDQAPFFPNPPYYAALFENRAIGTNVTVMQAIDNDDPNAGGNTKIIY 2881

Query: 295  TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET--QAKYQLLVTATDGGDPPRSATATX 352
            ++ D +  G     +TID  SG V +   +DRE   +  +++ V ATD G P  S T   
Sbjct: 2882 SLEDNN--GGY---VTIDSSSGLVTSIKMVDREALQEDSFKVTVRATDQGQPALSGTTVL 2936

Query: 353  XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRG 410
                         F+   Y   ++E    G  V  + ATD D   +  ++Y I  GN   
Sbjct: 2937 QVFFEDENDHKPKFVRQYYYASVSESTRTGVAVTRVEATDEDTGYNGMMNYFIVQGNEPY 2996

Query: 411  RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG----RSDTAMVQINITDANNYA 466
             F I  +   G++ V+  LDF+ ++ Y L V  +D G       + A V +NITD N + 
Sbjct: 2997 AFFIEPRT--GVVRVSGILDFESKKSYELIVMVSDMGMPQLLADNLAYVFVNITDDNTHP 3054

Query: 467  PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
            P F    + ASV ED P+G +VL + ATD D  +++   + +SS   +E       +   
Sbjct: 3055 PRFAQKVHEASVREDVPLGYSVLTIKATDIDT-VDSFHRFLISS--GDEENMFTITESES 3111

Query: 527  NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586
               T  IT    LDRE  S Y + V   D      SD   V+I+V D NDN P F+   +
Sbjct: 3112 EKMTAIITVRGKLDRERKSFYNMIVVVND--TSGQSDECIVKITVTDANDNGPHFQPSYF 3169

Query: 587  TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK--- 643
            +  + E+      V+ + ATD D+  NG          ++   F I  ++    T +   
Sbjct: 3170 SGFVRENIDSEQFVTTISATDPDMPSNGPPFTFTLINTKQSSQFRIKDSTVTSNTAQVFA 3229

Query: 644  --ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701
                DRE    + L   A D G P   +   +++ + D+N+  P+  ++ +     + + 
Sbjct: 3230 YGTFDRELTPFYKLLVNASDSGRPAMWNHTYIYVDVLDVNEHEPIDGNNTIIVNALDGAF 3289

Query: 702  IGTTIGEIRAHDPD 715
             G  IG     D D
Sbjct: 3290 AGGVIGRPYYQDDD 3303



 Score =  207 bits (506), Expect = 3e-51
 Identities = 186/688 (27%), Positives = 316/688 (45%), Gaps = 63/688 (9%)

Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV--IAKIKATDADVGANSAIRY 189
           +  T+ V I D N+  P F    Y  +V E  S  D  V  +    A D D G  S+  Y
Sbjct: 103 TATTLLVTIKDSNNFLPTFGSSVYNGTVMEG-SKEDTVVKGLENCHAEDRDTGGISS--Y 159

Query: 190 AIIGGNTQMQFSIDSLS-GDVSLVKTLDYE------QVRSYRLVIRAQDGGSPSRSNTTQ 242
            II GN +  F   +++ G+   ++ L  +         + +LV+ A+D GSP+R+ TTQ
Sbjct: 160 TIISGNEKGYFKTSTINVGEERFLQILTTDLPITRDTTNTIKLVVEARDSGSPARTVTTQ 219

Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
           + I++ + N+N P+F    +   V E   +   + RV A D D+G++  + Y      Y 
Sbjct: 220 IHISVENRNENTPKFEKEEYTAMVMEETQLNSPVARVHAKDTDQGMSGSVYY------YL 273

Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT------------A 350
             +    T++P +G V   G LD + Q+ YQL V ATD G P R A             +
Sbjct: 274 SPLSSYFTVNPITGVVILVGTLDYQKQSSYQLTVMATDRGSPRREAATKVILTIKDSQFS 333

Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGN 407
                          F        + ED P    V   TATD D    + RL Y ++G  
Sbjct: 334 PPADSADPGANTAPVFTRKALATTVREDLPKNGFVFLATATDNDPPGPNQRLLYSLSGPE 393

Query: 408 TRGRFSITSQNGRGLITVAQPLDFKQERRYV-LTVSATDSGGRSDTA----MVQINITDA 462
             G F+I   +   ++T+A  LD+++    + LTV+ATD G  + +A    +V I   D 
Sbjct: 394 A-GLFAIDPDS--AVVTLAAALDYEKGPTVINLTVTATDQGSPALSASAPLIVYIKDVDE 450

Query: 463 NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522
           N   PVF+      SV ED  +GT++    ATD D G + ++ YS+   ++ E V +   
Sbjct: 451 NQNLPVFDPKAQAISVKEDTALGTSIFTAKATDEDSGPDGELEYSM---VAGEGVGY--- 504

Query: 523 QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582
             ++N  TG +TT  + DR+T     + + A D G    +    + I V  V+D  P F 
Sbjct: 505 -VILNETTGVVTTAAMFDRKTNPVVEVVIAAHDKGTFPRTSKFYLLIQVEKVDDMYPEFT 563

Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642
           Q  Y+A +++ +   T V  + ATD +   N +I Y L      +  F ++ ++GVIRT 
Sbjct: 564 QPAYSATVLDGSPENTFVVALHATDYE---NTQIEYRLVNVGVND-LFQVERSTGVIRTA 619

Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
           +    ++    +   + I+     + +  +V+I I+   +  P F +      + ENS  
Sbjct: 620 RE-PAKTRGDQEFNQLIIEASDKTRQAITLVNILIKSTKEVVPRFTTSAFEIKVPENSGP 678

Query: 703 GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762
             ++  + A D D G    + YSI GG  +  F+++  Q S K  ++   D + E+    
Sbjct: 679 FDSLVCLAATDGDLGS---ITYSITGG-GNGKFAVD--QHSGKFSVLRSFDYELEN---G 729

Query: 763 YELVIRAASP-PLWNDVRVEILVTDVND 789
           Y + ++A +P    +   V++++++++D
Sbjct: 730 YIVQVQAETPNAKTSSANVKLIISNIDD 757



 Score =  198 bits (484), Expect = 1e-48
 Identities = 189/687 (27%), Positives = 311/687 (45%), Gaps = 62/687 (9%)

Query: 52   IGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA 111
            + +N +V   I  +TA   +P +           + D F ++ +    L +A LD E  A
Sbjct: 1195 VPENKQVGTEIGAITATYADP-NTLLKYSITRGNIDDTFCVNSKGVISLAKA-LDSETKA 1252

Query: 112  RYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVI 171
             +T+    +   S      + T  + + + D NDN+P   E  Y V V ED +      +
Sbjct: 1253 SFTLDAMVSHGTS------NHTTVVQITVNDINDNWP-IMEPVYNVEVREDQA--PGTEL 1303

Query: 172  AKIKATDADVGANSAIRYAIIG----GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVI 227
             K+ ATD D G    I Y II     G++ + F++++ +G ++LV+ LD E +  + L +
Sbjct: 1304 VKVVATDLDGGVGGTITYTIIQTQDIGSSSL-FAVNASTGVITLVQKLDAEDINKHVLYV 1362

Query: 228  RAQDGG-SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE 286
            +A+DGG +P  +  T++++ + DVND+APRF +S +  SV    P+ + + +V A DAD 
Sbjct: 1363 KAEDGGPTPKYAAITKVVVLVGDVNDHAPRFSSSQYLASVPYEFPVNFHVFQVIATDADS 1422

Query: 287  GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR 346
            G NAELTY +T     GN D    I+  +G V  +  L    + K++L + ATD G P R
Sbjct: 1423 GSNAELTYAITG----GNEDGIFKINSENGLVSLARPLASSAKIKHKLSLKATDNGVPRR 1478

Query: 347  SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG 406
              T+T              F      V + E   PG  V T+  T +     + Y I  G
Sbjct: 1479 IGTST-IIVFVILADLLPKFPVSPLIVNVKEGVLPGGRVTTVKMTSS---RLMTYRILEG 1534

Query: 407  NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYA 466
            N  G F + S +G   +   + LD++  R + + +   D+ G +D   + +N+ D N+ +
Sbjct: 1535 NDEGYFRMDSLSGD--LLALKELDYEDVRTFTMRIKGQDTDGNADVVTLVVNLEDVNDCS 1592

Query: 467  PVFENAPYTASVFE-DAPI---GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522
            PVF        +   + P    G  V+ +   D D G   ++T+ LS E         ++
Sbjct: 1593 PVFAGEVGGEVMLRVEEPFLVAGVPVVKLDVYDKDAG--DRLTFELSDE--------GER 1642

Query: 523  QFVINPQTGAITTNKLLD-RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581
             F I+ +   I T  + D  E +S    TVT RD   P    ++ V ++   + +  PV 
Sbjct: 1643 IFTIDDEGQLIPTRSVNDITEPLS---FTVTVRDSASPPHVTSSRVTLNFEKLGEALPV- 1698

Query: 582  KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641
                  + + EDA +G  V+ V           +I Y  DP      +F ID   G IR 
Sbjct: 1699 -----ESRVREDAYIGMIVTFVPKVFPKSVF--KITYPKDP------AFSIDEI-GDIRV 1744

Query: 642  NKALDRESVATHDLKAVAIDG-GTPPQSSTVIVHIKIEDINDSPPVFESDCLTF-YISEN 699
             K LD E   ++ L     +  G+ P+    +V I + D+ND+ P F      +  I++N
Sbjct: 1745 AKPLDFEKQVSYTLTVREAESIGSSPRVFDRVVVISVIDVNDNVPRFTGITRIYKRINKN 1804

Query: 700  SPIGTTIGEIRAHDPDEGPNAVVHYSI 726
            S  G+ +  + A D D   N  V + I
Sbjct: 1805 SLNGSPVLSLNALDLDYERNGEVGFQI 1831



 Score =  197 bits (481), Expect = 3e-48
 Identities = 240/891 (26%), Positives = 383/891 (42%), Gaps = 112/891 (12%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            QI V D ND+ P+ E   Y   VRE  + GT ++ + ATD D G    + YTI       
Sbjct: 1272 QITVNDINDNWPIME-PVYNVEVREDQAPGTELVKVVATDLDGGVGGTITYTI------- 1323

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            +  +D              +F ++  +G +     LD E + ++ + VKA D   P    
Sbjct: 1324 IQTQDIGSSS---------LFAVNASTGVITLVQKLDAEDINKHVLYVKAED-GGPTPKY 1373

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             + T  + V + D ND+ P+FS   Y  SV  +  V  N  + ++ ATDAD G+N+ + Y
Sbjct: 1374 AAITKVV-VLVGDVNDHAPRFSSSQYLASVPYEFPV--NFHVFQVIATDADSGSNAELTY 1430

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            AI GGN    F I+S +G VSL + L       ++L ++A D G P R  T+ +++ +  
Sbjct: 1431 AITGGNEDGIFKINSENGLVSLARPLASSAKIKHKLSLKATDNGVPRRIGTSTIIVFVI- 1489

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            + D  P+F  S    +V E V  G  +  V+   +       +TY + +    GN +   
Sbjct: 1490 LADLLPKFPVSPLIVNVKEGVLPGGRVTTVKMTSS-----RLMTYRILE----GNDEGYF 1540

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             +D  SG +    +LD E    + + +    G D   +A                    G
Sbjct: 1541 RMDSLSGDLLALKELDYEDVRTFTMRIK---GQDTDGNADVVTLVVNLEDVNDCSPVFAG 1597

Query: 370  QY--EVELAEDEP---PGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG----R 420
            +   EV L  +EP    G PVV L   D D  +RL +E++    R  F+I  +      R
Sbjct: 1598 EVGGEVMLRVEEPFLVAGVPVVKLDVYDKDAGDRLTFELSDEGER-IFTIDDEGQLIPTR 1656

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
             +  + +PL F        TV+  DS         ++ +    N+  + E  P  + V E
Sbjct: 1657 SVNDITEPLSF--------TVTVRDSASPPHVTSSRVTL----NFEKLGEALPVESRVRE 1704

Query: 481  DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
            DA IG  V  V           +ITY              D  F I+ + G I   K LD
Sbjct: 1705 DAYIGMIVTFVPKVFPKSVF--KITYP------------KDPAFSID-EIGDIRVAKPLD 1749

Query: 541  RETMSGYLLTVTARD--GGVPSLSDTTDVEISVVDVNDNEPVFK--QQLYTANIMEDALV 596
             E    Y LTV   +  G  P + D   V ISV+DVNDN P F    ++Y   I +++L 
Sbjct: 1750 FEKQVSYTLTVREAESIGSSPRVFDRV-VVISVIDVNDNVPRFTGITRIYK-RINKNSLN 1807

Query: 597  GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
            G+ V  + A D D   NG + +++ P+D   G F I+P   +I T   L++ES   ++  
Sbjct: 1808 GSPVLSLNALDLDYERNGEVGFQIVPRD---GPFGINPVDEMIETTGNLNKES---YEFD 1861

Query: 657  AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE-----SDCLTFYISENSPIGTTIGEIRA 711
              A D G P  +ST I    +  + + PP+FE      +   F  +E S  G  IG ++A
Sbjct: 1862 VYAFDYGIPRLNSTTIP--MVVHVAEVPPIFEVLDNDHNMYRFETAETSHGGELIGTVKA 1919

Query: 712  HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771
                +   A++ Y I  G+  NSF + T  G    E+     ++YE     Y L + A+ 
Sbjct: 1920 VSYSK---ALIAYEITSGNVRNSFKIGTLTG----EIRHNNFMNYEIHENVYNLTVTASE 1972

Query: 772  -PPLWNDVRVEILV--TDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVT--- 824
              P  +   + +++   ++NDN P      +      +  PVG    +V A D D +   
Sbjct: 1973 LIPRGHQTEIPVIIHLKNINDNYPRFTK-SLFTTAVNEDVPVGTSILQVTATDCDCSKSC 2031

Query: 825  ----DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
                 +L Y I   +N ++  ++  TG ++ +  L+  +     + V V D
Sbjct: 2032 LCAPGELTYSI---DNTDMFAISPDTGVISPAVSLDYEMSSWVVLVVKVED 2079



 Score =  176 bits (429), Expect = 6e-42
 Identities = 223/931 (23%), Positives = 390/931 (41%), Gaps = 102/931 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I+V + N+++P FE ++Y A V E     + V  + A D D G +  V Y         L
Sbjct: 222  ISVENRNENTPKFEKEEYTAMVMEETQLNSPVARVHAKDTDQGMSGSVYYY--------L 273

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +P             +   F ++  +G ++   +LD +K + Y + V ATD+ SP  +  
Sbjct: 274  SP-------------LSSYFTVNPITGVVILVGTLDYQKQSSYQLTVMATDRGSPRREAA 320

Query: 131  SSTA-TIH-------VNIIDDNDNY-PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181
            +    TI         +  D   N  P F+ K    +V ED+    N  +    ATD D 
Sbjct: 321  TKVILTIKDSQFSPPADSADPGANTAPVFTRKALATTVREDLP--KNGFVFLATATDNDP 378

Query: 182  -GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY-RLVIRAQDGGSPSRSN 239
             G N  + Y++ G    + F+ID  S  V+L   LDYE+  +   L + A D GSP+ S 
Sbjct: 379  PGPNQRLLYSLSGPEAGL-FAIDPDSAVVTLAAALDYEKGPTVINLTVTATDQGSPALSA 437

Query: 240  TTQLLINIRDV--NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297
            +  L++ I+DV  N N P F       SV E+  +G SI   +A D D G + EL Y+M 
Sbjct: 438  SAPLIVYIKDVDENQNLPVFDPKAQAISVKEDTALGTSIFTAKATDEDSGPDGELEYSMV 497

Query: 298  DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357
              +  G V L  T    +G V T+   DR+T    ++++ A D G  PR++         
Sbjct: 498  AGEGVGYVILNET----TGVVTTAAMFDRKTNPVVEVVIAAHDKGTFPRTSKFYLLIQVE 553

Query: 358  XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ 417
                    F    Y   + +  P  T VV L ATD  E+ ++ Y +        F +   
Sbjct: 554  KVDDMYPEFTQPAYSATVLDGSPENTFVVALHATDY-ENTQIEYRLVNVGVNDLFQVERS 612

Query: 418  NGRGLITVAQPLDFKQERRY-VLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA 476
             G  + T  +P   + ++ +  L + A+D   ++ T +V I I       P F  + +  
Sbjct: 613  TGV-IRTAREPAKTRGDQEFNQLIIEASDKTRQAIT-LVNILIKSTKEVVPRFTTSAFEI 670

Query: 477  SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
             V E++    +++ ++ATD D+G    ITYS++   + +        F ++  +G  +  
Sbjct: 671  KVPENSGPFDSLVCLAATDGDLG---SITYSITGGGNGK--------FAVDQHSGKFSVL 719

Query: 537  KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
            +  D E  +GY++ V A      + S    + IS +D   + P F +  YT  + E    
Sbjct: 720  RSFDYELENGYIVQVQAETPNAKTSSANVKLIISNID---DLPSFAKPEYTLTVPEGTTP 776

Query: 597  GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
            GT++          G +G    + D    + G  +++  S  +  +  ++R      + +
Sbjct: 777  GTTILD--------GSSGFQFVDDDTNPEQFGCSLMEVTSMFVLEHFRVERSD---SECR 825

Query: 657  AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY---ISENSPIGTTIGEIRAHD 713
               I       S T    + ++  N + P  ++     Y   +S ++P  T I  + A D
Sbjct: 826  LTVIKSLFEHHSVTQFTFL-VQVTNKAFPNIQATAKASYWATVSSDTPTRTPIVTVTASD 884

Query: 714  PD--EGPNAVVHYSIKGGDDS--NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
             D  EG   V+   +   D S  N F +++  G       T+   +  +   +Y+L ++A
Sbjct: 885  LDKEEGNQQVLFQFVSDADSSGQNRFQIDSSTG-------TITSTNLLAANNEYKLTVKA 937

Query: 770  A---SPPLWNDVRVEI-LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD 825
                SPP+ + V V + ++T +    PV           ++   +G    V    A    
Sbjct: 938  TDTGSPPMESQVSVTVSVITPIT--TPVKFAEANYAKTIQESLVIG--NSVLQVTATGPA 993

Query: 826  KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVR 885
             + Y I+ GN  +   ++ TTG + ++  L+  V +   + V  T      K   +++V 
Sbjct: 994  AITYSIVGGNKNDAFRIDRTTGQIAVNKPLDYEVLQSYVLNVRATCETYTPKIAAEVAVA 1053

Query: 886  LITEEM-------LL--NSITVRLNDMTAEQ 907
            +   ++       LL  N  TV +N  T EQ
Sbjct: 1054 ITLTDVNDNSPVFLLYSNPTTVTVNSYTPEQ 1084



 Score =  167 bits (407), Expect = 3e-39
 Identities = 190/722 (26%), Positives = 304/722 (42%), Gaps = 76/722 (10%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLK---ATDQDIGKNAEVEYTIELVTA 67
           + + D N+  P F    Y  +V EG+   T V  L+   A D+D G  +   YTI  ++ 
Sbjct: 109 VTIKDSNNFLPTFGSSVYNGTVMEGSKEDTVVKGLENCHAEDRDTGGISS--YTI--ISG 164

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
           +    E             +   +I      L T   + R+      ++V+A D  SP  
Sbjct: 165 N----EKGYFKTSTINVGEERFLQI------LTTDLPITRDTTNTIKLVVEARDSGSPAR 214

Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
              + T  IH+++ + N+N P+F ++ YT  V E+  +  N  +A++ A D D G + ++
Sbjct: 215 ---TVTTQIHISVENRNENTPKFEKEEYTAMVMEETQL--NSPVARVHAKDTDQGMSGSV 269

Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            Y +        F+++ ++G V LV TLDY++  SY+L + A D GSP R   T++++ I
Sbjct: 270 YYYL--SPLSSYFTVNPITGVVILVGTLDYQKQSSYQLTVMATDRGSPRREAATKVILTI 327

Query: 248 RDVN------------DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTY 294
           +D              + AP F       +V E++P    +    A D D  G N  L Y
Sbjct: 328 KDSQFSPPADSADPGANTAPVFTRKALATTVREDLPKNGFVFLATATDNDPPGPNQRLLY 387

Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET-QAKYQLLVTATDGGDPPRSATATXX 353
           +++  +  G       IDP S  V  +  LD E       L VTATD G P  SA+A   
Sbjct: 388 SLSGPE-AG----LFAIDPDSAVVTLAAALDYEKGPTVINLTVTATDQGSPALSASAPLI 442

Query: 354 XXXXXXXXXXX--XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTR 409
                         F P    + + ED   GT + T  ATD D   D  L Y +  G   
Sbjct: 443 VYIKDVDENQNLPVFDPKAQAISVKEDTALGTSIFTAKATDEDSGPDGELEYSMVAGEGV 502

Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAP 467
           G + I ++   G++T A   D K      + ++A D G   R+    + I +   ++  P
Sbjct: 503 G-YVILNET-TGVVTTAAMFDRKTNPVVEVVIAAHDKGTFPRTSKFYLLIQVEKVDDMYP 560

Query: 468 VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527
            F    Y+A+V + +P  T V+ + ATD +   N QI Y L +   N+        F + 
Sbjct: 561 EFTQPAYSATVLDGSPENTFVVALHATDYE---NTQIEYRLVNVGVNDL-------FQVE 610

Query: 528 PQTGAITTNK--LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585
             TG I T +     R       L + A D    +    T V I +    +  P F    
Sbjct: 611 RSTGVIRTAREPAKTRGDQEFNQLIIEASD---KTRQAITLVNILIKSTKEVVPRFTTSA 667

Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645
           +   + E++    S+  + ATD D+   G I Y +       G F +D  SG     ++ 
Sbjct: 668 FEIKVPENSGPFDSLVCLAATDGDL---GSITYSI--TGGGNGKFAVDQHSGKFSVLRSF 722

Query: 646 DRESVATHDLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
           D E     +   V +   TP  ++S+  V + I +I+D P  F     T  + E +  GT
Sbjct: 723 DYE---LENGYIVQVQAETPNAKTSSANVKLIISNIDDLPS-FAKPEYTLTVPEGTTPGT 778

Query: 705 TI 706
           TI
Sbjct: 779 TI 780



 Score =  163 bits (396), Expect = 6e-38
 Identities = 221/911 (24%), Positives = 377/911 (41%), Gaps = 91/911 (9%)

Query: 2    SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
            S P  ++  I  +D N + PVF+ +    SV+E  + GT++ T KATD+D G + E+EY+
Sbjct: 438  SAPLIVY--IKDVDENQNLPVFDPKAQAISVKEDTALGTSIFTAKATDEDSGPDGELEYS 495

Query: 62   IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121
              +V  + +                     ++  +G + T A  DR+      V++ A D
Sbjct: 496  --MVAGEGVG-----------------YVILNETTGVVTTAAMFDRKTNPVVEVVIAAHD 536

Query: 122  QAS-PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD 180
            + + P + +      I V  +D  D YP+F++  Y+ +V +     +N  +  + ATD +
Sbjct: 537  KGTFPRTSKF--YLLIQVEKVD--DMYPEFTQPAYSATVLD--GSPENTFVVALHATDYE 590

Query: 181  VGANSAIRYAIIGGNTQMQFSIDSLSGDVSL----VKTLDYEQVRSYRLVIRAQDGGSPS 236
               N+ I Y ++       F ++  +G +       KT   ++    +L+I A D    +
Sbjct: 591  ---NTQIEYRLVNVGVNDLFQVERSTGVIRTAREPAKTRGDQEFN--QLIIEASD---KT 642

Query: 237  RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
            R   T + I I+   +  PRF TS F+  V EN     S+V + A D D G    +TY++
Sbjct: 643  RQAITLVNILIKSTKEVVPRFTTSAFEIKVPENSGPFDSLVCLAATDGDLG---SITYSI 699

Query: 297  TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
                 TG  +    +D  SG        D E +  Y + V A     P    ++      
Sbjct: 700  -----TGGGNGKFAVDQHSGKFSVLRSFDYELENGYIVQVQAE---TPNAKTSSANVKLI 751

Query: 357  XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITS 416
                     F   +Y + + E   PGT ++  ++     D+  + E  G +      +TS
Sbjct: 752  ISNIDDLPSFAKPEYTLTVPEGTTPGTTILDGSSGFQFVDDDTNPEQFGCSL---MEVTS 808

Query: 417  QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSD-TAMVQINITDANNYAPVFENAPYT 475
                    V +      E R  +  S  +    +  T +VQ+      N       A Y 
Sbjct: 809  MFVLEHFRVERS---DSECRLTVIKSLFEHHSVTQFTFLVQVTNKAFPNIQAT-AKASYW 864

Query: 476  ASVFEDAPIGTTVLVVSATDSDVGI-NAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
            A+V  D P  T ++ V+A+D D    N Q+ +   S+  +        +F I+  TG IT
Sbjct: 865  ATVSSDTPTRTPIVTVTASDLDKEEGNQQVLFQFVSDADSSG----QNRFQIDSSTGTIT 920

Query: 535  TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
            +  LL     + Y LTV A D G P +     V +SV+        F +  Y   I E  
Sbjct: 921  STNLL--AANNEYKLTVKATDTGSPPMESQVSVTVSVITPITTPVKFAEANYAKTIQESL 978

Query: 595  LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654
            ++G SV QV AT         I Y +   ++ + +F ID  +G I  NK LD E + ++ 
Sbjct: 979  VIGNSVLQVTATGP-----AAITYSIVGGNKND-AFRIDRTTGQIAVNKPLDYEVLQSYV 1032

Query: 655  LKAVA-IDGGTPPQSSTVIVHIKIEDINDSPPVF--ESDCLTFYISENSPIGTTIGEIR- 710
            L   A  +  TP  ++ V V I + D+ND+ PVF   S+  T  ++  +P  T + + R 
Sbjct: 1033 LNVRATCETYTPKIAAEVAVAITLTDVNDNSPVFLLYSNPTTVTVNSYTPEQTVVFKARR 1092

Query: 711  -----------AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759
                       A D D      V YSI     + S  L     +   ++ T   + Y S 
Sbjct: 1093 FTYYVIYEKALAVDADSESFGTVRYSINSASSNPSSDLPFSLDASSGQMKTTRVIKY-SD 1151

Query: 760  RKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPA 818
            R +Y + +  A+          +++   N N P          +  +   VG   G + A
Sbjct: 1152 RAEYTVAL-VATDGGGKSTTTSLVIKVFNINEPPKFPQPKYEFSVPENKQVGTEIGAITA 1210

Query: 819  YDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKA 878
              AD    L+Y I  GN  +   +N + G ++L+  L++      T++  V+ G +    
Sbjct: 1211 TYADPNTLLKYSITRGNIDDTFCVN-SKGVISLAKALDSETKASFTLDAMVSHGTSNHTT 1269

Query: 879  MMQLSVRLITE 889
            ++Q++V  I +
Sbjct: 1270 VVQITVNDIND 1280



 Score =  157 bits (382), Expect = 3e-36
 Identities = 141/563 (25%), Positives = 249/563 (44%), Gaps = 42/563 (7%)

Query: 206 SGDVSLVKTLDYE--QVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263
           +G V+  K  +Y   +  ++ L I  +          T LL+ I+D N+  P F +S++ 
Sbjct: 68  AGVVTSAKPFEYRIGESNTFTLTIVKRQRSQVFGGTATTLLVTIKDSNNFLPTFGSSVYN 127

Query: 264 ESVSENVP---IGYSIVRVQAYDADEG-VNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319
            +V E      +   +    A D D G +++    +  +K Y     + +  +     + 
Sbjct: 128 GTVMEGSKEDTVVKGLENCHAEDRDTGGISSYTIISGNEKGYFKTSTINVGEERFLQILT 187

Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE 379
           T   + R+T    +L+V A D G P R+ T                F   +Y   + E+ 
Sbjct: 188 TDLPITRDTTNTIKLVVEARDSGSPARTVTTQIHISVENRNENTPKFEKEEYTAMVMEET 247

Query: 380 PPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437
              +PV  + A D D+     ++Y ++  ++   F++    G  ++ +   LD++++  Y
Sbjct: 248 QLNSPVARVHAKDTDQGMSGSVYYYLSPLSSY--FTVNPITG--VVILVGTLDYQKQSSY 303

Query: 438 VLTVSATDSGG--RSDTAMVQINITDAN------------NYAPVFENAPYTASVFEDAP 483
            LTV ATD G   R     V + I D+             N APVF       +V ED P
Sbjct: 304 QLTVMATDRGSPRREAATKVILTIKDSQFSPPADSADPGANTAPVFTRKALATTVREDLP 363

Query: 484 IGTTVLVVSATDSDV-GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
               V + +ATD+D  G N ++ YSLS   +          F I+P +  +T    LD E
Sbjct: 364 KNGFVFLATATDNDPPGPNQRLLYSLSGPEAG--------LFAIDPDSAVVTLAAALDYE 415

Query: 543 TMSGYL-LTVTARDGGVPSLSDTTDVEISVVDVNDNE--PVFKQQLYTANIMEDALVGTS 599
                + LTVTA D G P+LS +  + + + DV++N+  PVF  +    ++ ED  +GTS
Sbjct: 416 KGPTVINLTVTATDQGSPALSASAPLIVYIKDVDENQNLPVFDPKAQAISVKEDTALGTS 475

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
           +    ATD D G +G + Y +   +   G  +++  +GV+ T    DR++    ++   A
Sbjct: 476 IFTAKATDEDSGPDGELEYSMVAGEGV-GYVILNETTGVVTTAAMFDRKTNPVVEVVIAA 534

Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
            D GT P++S   + I++E ++D  P F     +  + + SP  T +  + A D +   N
Sbjct: 535 HDKGTFPRTSKFYLLIQVEKVDDMYPEFTQPAYSATVLDGSPENTFVVALHATDYE---N 591

Query: 720 AVVHYSIKGGDDSNSFSLETRQG 742
             + Y +     ++ F +E   G
Sbjct: 592 TQIEYRLVNVGVNDLFQVERSTG 614



 Score =  146 bits (354), Expect = 8e-33
 Identities = 127/483 (26%), Positives = 220/483 (45%), Gaps = 47/483 (9%)

Query: 421 GLITVAQPLDFK--QERRYVLTVSATDS----GGRSDTAMVQINITDANNYAPVFENAPY 474
           G++T A+P +++  +   + LT+         GG + T +V I   D+NN+ P F ++ Y
Sbjct: 69  GVVTSAKPFEYRIGESNTFTLTIVKRQRSQVFGGTATTLLVTIK--DSNNFLPTFGSSVY 126

Query: 475 TASVFEDAPIGTTVLVVS---ATDSDVGINAQITYSLSSE---ISNEAVAHHDQQFVINP 528
             +V E +   T V  +    A D D G  +  T    +E        +   +++F+   
Sbjct: 127 NGTVMEGSKEDTVVKGLENCHAEDRDTGGISSYTIISGNEKGYFKTSTINVGEERFL--- 183

Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588
               +TT+  + R+T +   L V ARD G P+ + TT + ISV + N+N P F+++ YTA
Sbjct: 184 --QILTTDLPITRDTTNTIKLVVEARDSGSPARTVTTQIHISVENRNENTPKFEKEEYTA 241

Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648
            +ME+  + + V++V A D D G++G ++Y L P       F ++P +GV+     LD +
Sbjct: 242 MVMEETQLNSPVARVHAKDTDQGMSGSVYYYLSPL---SSYFTVNPITGVVILVGTLDYQ 298

Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP------------PVFESDCLTFYI 696
             +++ L  +A D G+P + +   V + I+D   SP            PVF    L   +
Sbjct: 299 KQSSYQLTVMATDRGSPRREAATKVILTIKDSQFSPPADSADPGANTAPVFTRKALATTV 358

Query: 697 SENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755
            E+ P    +    A D D  GPN  + YS+  G ++  F+++     D A +     LD
Sbjct: 359 REDLPKNGFVFLATATDNDPPGPNQRLLYSL-SGPEAGLFAID----PDSAVVTLAAALD 413

Query: 756 YESPRKKYELVIRA---ASPPLWNDVRVEILVTDV--NDNAPVM-KDFQIIFNNYKDCFP 809
           YE       L + A    SP L     + + + DV  N N PV     Q I         
Sbjct: 414 YEKGPTVINLTVTATDQGSPALSASAPLIVYIKDVDENQNLPVFDPKAQAISVKEDTALG 473

Query: 810 VGPF-GRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVS 868
              F  +    D+    +L+Y +++G     ++LNETTG +T +   +     +  + ++
Sbjct: 474 TSIFTAKATDEDSGPDGELEYSMVAGEGVGYVILNETTGVVTTAAMFDRKTNPVVEVVIA 533

Query: 869 VTD 871
             D
Sbjct: 534 AHD 536



 Score = 45.6 bits (103), Expect = 0.020
 Identities = 35/110 (31%), Positives = 48/110 (43%), Gaps = 7/110 (6%)

Query: 1245 CEIPTETCHRFLDLTG--PLQIGGLPNIPSSF-QVKNKDFVGCISDFYIDHKFIDLNSYV 1301
            C+I   T    L L G  PLQ+GG+ N   S+  +    FVGCI +        DL+  +
Sbjct: 3742 CQITGTTVGTDLVLNGVWPLQVGGVSNTELSYPSLVYTGFVGCIRNLVDFGDMYDLDKPL 3801

Query: 1302 ADNGTLAGCPEKRSRCSSAPCYNGAECS-DLWDTYICDCKEGHTGKDCAD 1350
                +  GC E   RC   PC + + C   +     C C  G TG +C D
Sbjct: 3802 VQVNSAKGC-ELAMRCP--PCGSDSYCEPQINRASYCVCNLGKTGFECKD 3848



 Score = 38.3 bits (85), Expect = 3.0
 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 8/80 (10%)

Query: 1271 PSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNG--TLAGCPEKRSRCSSAPCYNGAEC 1328
            P+S + K+ DF GC+SD   +   +D +  V       + GCP     C    C+N   C
Sbjct: 4157 PNSTKAKS-DFEGCVSDHRYNGYHMDKDRTVDRYQWRVIKGCP-----CEPGGCFNNGTC 4210

Query: 1329 SDLWDTYICDCKEGHTGKDC 1348
                    C C+ G+TG  C
Sbjct: 4211 MANATIPTCKCQPGYTGLTC 4230


>UniRef50_Q17LY6 Cluster: Cadherin; n=6; Culicidae|Rep: Cadherin -
            Aedes aegypti (Yellowfever mosquito)
          Length = 1653

 Score =  314 bits (770), Expect = 3e-83
 Identities = 369/1507 (24%), Positives = 614/1507 (40%), Gaps = 171/1507 (11%)

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
            +IRY I  GN    F+I + +G + + K LDYE+++ Y L +   D     + N T +L+
Sbjct: 7    SIRYKITSGNIGDVFAIHNTTGALYVAKALDYEKIKKYELRLTVSDS---FKENYTTVLV 63

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYS--IVRVQAYDADEGVNAELTYTMTDK--DY 301
            N++DVNDN P F  S ++  ++E    G    ++RV A DAD    + + Y +T    D 
Sbjct: 64   NVKDVNDNPPVFERSSYRTQITEEDDRGLPKRVMRVTASDADVERPSNIIYFLTGPGIDI 123

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRET---QAKYQLLVTATDGGDPPRSATATXXXXXXX 358
                +    I+  +G ++    L+R+    +  ++  V A D G                
Sbjct: 124  ENPSESNFDINKATGEIFVLKPLNRDPPHGRPLWKFTVFAQDEGGEGLVGFTEVQIKLKD 183

Query: 359  XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQ 417
                   F  G Y   + E+   G  V+T+ A D D+ D   H +I     +   +I  +
Sbjct: 184  INDNAPSFPQGIYYGNVTENGTVGMYVMTIKAQDNDDVDEGTHAKIVYSIEKN--AIEEE 241

Query: 418  NG---------RGLITVAQP-LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAP 467
             G          G+IT A   LD ++   Y L + ATD GG   T    I + D N+  P
Sbjct: 242  TGLPIFDINPDTGVITTAVCCLDREKTPDYSLQIVATDGGGLKGTGTASIKVKDLNDMPP 301

Query: 468  VFENAPYTASVFE-DAPI--GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524
             F    +   V E D  I     +L V+  D D   N Q     SS    +  A      
Sbjct: 302  HFTKDEWFVEVEETDGNILPEAPILTVTVNDDDEINNFQYKIIESSGYGADKFA----MI 357

Query: 525  VINPQTGAITTNKLLDRET---MSGYLLTVTARDG-GVPSLS----DTTDVEISVVDVND 576
              N  TG++   + LD E    ++G+   +   D  G+        D + V + + D+ND
Sbjct: 358  KNNDGTGSLRVVQPLDFEDPMQINGFRFRIQVTDNEGINDTDKYHVDHSWVIVKLKDIND 417

Query: 577  NEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS 636
            N P F++    A   E+  VG ++    A D D     +I Y ++     +  F I    
Sbjct: 418  NTPRFRRPHMEAYTSENDEVGKTLVSFKAIDIDKAGKSKITYMINRATDRKRQFSISD-E 476

Query: 637  GVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696
            G +   + LDRE+++ ++L+ +AID G PP+++T  + ++++D+ND+ PVF  +     +
Sbjct: 477  GTVTIQRQLDREAISKYNLEILAIDDGVPPRTATATLTVEVKDVNDNAPVFAEEYRPILL 536

Query: 697  SENSPIGTTIGEIRAHDPDE-----GPNAVVHYSIKGGD-DSNSFSLETRQGSDKAELVT 750
             ENSP    I EI A D D+     GP           D    SF +E     D   +V+
Sbjct: 537  -ENSPASKII-EISAIDQDDRRMENGPPFQFRMDPDADDVIRTSFKVEQNNKGDGMAVVS 594

Query: 751  MVDLDYESPRKKYE--LVIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC 807
             +       RK+YE  +VI+ + +P       + + + DVNDN       +++  NY+  
Sbjct: 595  SLRSFDREYRKQYEIPIVIKDSGNPAQTGTSTLTVTIGDVNDNIMQPGSKEVVVYNYQGQ 654

Query: 808  FPVGPFGRVPAYDA---DVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLAT 864
             P  P GRV   D    D +DKL Y     N      L++T+G +T+         KL  
Sbjct: 655  APDTPIGRVFVNDLDDWDTSDKLFYWDELENPR--FKLDDTSGMVTMRRGAREGRYKL-R 711

Query: 865  MEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFL-----------SPLL 913
             ++      +E  A M + V+ I+ E ++NS ++RL  +T E F+              L
Sbjct: 712  FKIYDRKHAHESHANMSVVVKHISYEAIVNSGSIRLLGITDEDFIRIWDYRTQNIFKSKL 771

Query: 914  GFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPT 973
              F + LA ++   K+N+ +FSVQ     +  I +V FSAR            + ++   
Sbjct: 772  ERFREKLAELLNIDKKNVDVFSVQ-IKQKSPAITDVRFSARN-----------AYYFKAV 819

Query: 974  HLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLF 1033
             L   V LH+  + +   + +   + + C+ E       C  +++       VN++    
Sbjct: 820  QLNGVVLLHKEDIEQAVGINITMVNIDECLVENGDCNGSCTHIMEVQANPSLVNANKTAL 879

Query: 1034 RPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCS 1093
              +   ++  C C       N      + SC+       C +G +C   + G      CS
Sbjct: 880  VGVQIKSTAECMC-------NAREYKQQQSCK----SHPCLNGGRCSDTKSG----IRCS 924

Query: 1094 IDAAYTTAVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNG------- 1146
                Y+   C+   RSF  + +  +P L    + H+ ++F T    GL+ YNG       
Sbjct: 925  CPPGYSGPRCQQTVRSFRGNGWAWYPSLDMCDKSHISVEFITTKAEGLIFYNGPIVPPDD 984

Query: 1147 -RYNERHDFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVE--GNVGDGSWHTVEIEY 1203
                ++ DF+ALEL        G P  RF    G G  E+ ++    + DG WH +++ +
Sbjct: 985  NNEQQQSDFIALEL------EQGYP--RFLIDYGSGTLELRIQTKNPLNDGDWHRIDLFW 1036

Query: 1204 FNRTITMILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQ 1263
                + MI+D C +   +  A D  +      F      A   +P    + +L+L  PLQ
Sbjct: 1037 DTERVKMIVDYC-RTAVITEADDGNI----VEFVDHTCQAAGRVP--QFNEYLNLNTPLQ 1089

Query: 1264 IGGLPNIPSSFQVKN-------KDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSR 1316
            IGG+      +             F GCI +F  +    DL+       T++GC   +  
Sbjct: 1090 IGGVFREKFDYTYNRWQYMPVAAGFEGCIRNFKHNGILYDLSHPGLSKSTMSGCVFTQEV 1149

Query: 1317 CSSAP----CYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLRP 1372
            C   P    C    +C   +D   C+C  G +G  C+  T  P  F     + +     P
Sbjct: 1150 CDLNPQVSKCLEHGKCIGNFDDAKCECNPGWSGTYCSLPT-TPTTFKTHSYVKYALSFEP 1208

Query: 1373 IQLPWLNALSIRTRQR--DAFVMS---------IQLKSGLLHYSY---NGET----MYLP 1414
             +      L  RTR+   + F +S         I+LK   L + Y   +G+     + L 
Sbjct: 1209 DKFTTQIQLRFRTRETFGELFRISDQHMREYGIIELKEAKLWFRYSLNSGQVEERDVSLS 1268

Query: 1415 MATLSDGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLA-NKIQGQYIGK---ILIGGLDT 1470
               + DG WH + I+  G+   + +D G         + +  Q   + K   +  GG   
Sbjct: 1269 AVEVDDGQWHVVRIQRYGSAAILELDGGEGANFNQSFSFDGHQWLSVDKQEGVYAGGKPE 1328

Query: 1471 TAGLLASDV--GFFEGCIQDVRIG---------TAQSLLNRPTVRENVRDGCQSRADCML 1519
              G+   +V   + + CI D+R+          T  +   + T+ +N+   C S   C  
Sbjct: 1329 YTGVKTFEVQADYQKSCIDDIRLDGKSLPLPPTTNGTQWGQATMAKNIERYCSSNNPCQN 1388

Query: 1520 SICPPYSKCVTSWDSSTCTCEAGRV----GPQCV--SACELGPC-GAARCVPDQTPKGYS 1572
            + CP   +CV  W+   C C  G +    G  C+  + C   PC     C+  +    Y 
Sbjct: 1389 AYCPEPFECVDLWNKYECACGDGMIISPEGKTCIDRNECLDYPCLNGGTCINQEPRFKYK 1448

Query: 1573 CACEPGY 1579
            C C   Y
Sbjct: 1449 CICPDSY 1455



 Score =  239 bits (586), Expect = 6e-61
 Identities = 190/671 (28%), Positives = 316/671 (47%), Gaps = 57/671 (8%)

Query: 86  VQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145
           + DVF I   +GAL    +LD EK+ +Y + +  +D          +  T+ VN+ D ND
Sbjct: 17  IGDVFAIHNTTGALYVAKALDYEKIKKYELRLTVSDSFK------ENYTTVLVNVKDVND 70

Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG------GNTQMQ 199
           N P F   +Y   + E+        + ++ A+DADV   S I Y + G        ++  
Sbjct: 71  NPPVFERSSYRTQITEEDDRGLPKRVMRVTASDADVERPSNIIYFLTGPGIDIENPSESN 130

Query: 200 FSIDSLSGDVSLVKTLDYEQVRS---YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256
           F I+  +G++ ++K L+ +       ++  + AQD G       T++ I ++D+NDNAP 
Sbjct: 131 FDINKATGEIFVLKPLNRDPPHGRPLWKFTVFAQDEGGEGLVGFTEVQIKLKDINDNAPS 190

Query: 257 FYTSLFQESVSENVPIGYSIVRVQAY---DADEGVNAELTYTMTDKDYTGNVDLPI-TID 312
           F   ++  +V+EN  +G  ++ ++A    D DEG +A++ Y++          LPI  I+
Sbjct: 191 FPQGIYYGNVTENGTVGMYVMTIKAQDNDDVDEGTHAKIVYSIEKNAIEEETGLPIFDIN 250

Query: 313 PRSGWVYTS-GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371
           P +G + T+   LDRE    Y L + ATDGG      T T              F   ++
Sbjct: 251 PDTGVITTAVCCLDREKTPDYSLQIVATDGGG--LKGTGTASIKVKDLNDMPPHFTKDEW 308

Query: 372 EVELAEDEP---PGTPVVTLTATDADEDNRLHYEI--TGGNTRGRFSITSQN-GRGLITV 425
            VE+ E +    P  P++T+T  D DE N   Y+I  + G    +F++   N G G + V
Sbjct: 309 FVEVEETDGNILPEAPILTVTVNDDDEINNFQYKIIESSGYGADKFAMIKNNDGTGSLRV 368

Query: 426 AQPLDFK---QERRYVLTVSATDSGGRSDT-------AMVQINITDANNYAPVFENAPYT 475
            QPLDF+   Q   +   +  TD+ G +DT       + V + + D N+  P F      
Sbjct: 369 VQPLDFEDPMQINGFRFRIQVTDNEGINDTDKYHVDHSWVIVKLKDINDNTPRFRRPHME 428

Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
           A   E+  +G T++   A D D    ++ITY +     N A     +QF I+ + G +T 
Sbjct: 429 AYTSENDEVGKTLVSFKAIDIDKAGKSKITYMI-----NRA-TDRKRQFSISDE-GTVTI 481

Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
            + LDRE +S Y L + A D GVP  + T  + + V DVNDN PVF ++ Y   ++E++ 
Sbjct: 482 QRQLDREAISKYNLEILAIDDGVPPRTATATLTVEVKDVNDNAPVFAEE-YRPILLENS- 539

Query: 596 VGTSVSQVGATDADVGL--NG-RIHYELDP--KDREEGSFVID-----PASGVIRTNKAL 645
             + + ++ A D D     NG    + +DP   D    SF ++         V+ + ++ 
Sbjct: 540 PASKIIEISAIDQDDRRMENGPPFQFRMDPDADDVIRTSFKVEQNNKGDGMAVVSSLRSF 599

Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
           DRE    +++  V  D G P Q+ T  + + I D+ND+     S  +  Y  +     T 
Sbjct: 600 DREYRKQYEIPIVIKDSGNPAQTGTSTLTVTIGDVNDNIMQPGSKEVVVYNYQGQAPDTP 659

Query: 706 IGEIRAHDPDE 716
           IG +  +D D+
Sbjct: 660 IGRVFVNDLDD 670



 Score =  132 bits (319), Expect = 1e-28
 Identities = 127/484 (26%), Positives = 220/484 (45%), Gaps = 54/484 (11%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQ---DIGKNAEVEYTIELVT 66
           QI + D ND++P F    Y  +V E  + G  V+T+KA D    D G +A++ Y+IE   
Sbjct: 178 QIKLKDINDNAPSFPQGIYYGNVTENGTVGMYVMTIKAQDNDDVDEGTHAKIVYSIE--- 234

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR-ASLDREKVARYTVLVKATDQASP 125
            + +  E               +F I+  +G + T    LDREK   Y++ + ATD    
Sbjct: 235 KNAIEEETGL-----------PIFDINPDTGVITTAVCCLDREKTPDYSLQIVATDGGG- 282

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE-DISVTDNPVIAKIKATDADVGAN 184
               L  T T  + + D ND  P F++  + V V+E D ++     I  +   D D   N
Sbjct: 283 ----LKGTGTASIKVKDLNDMPPHFTKDEWFVEVEETDGNILPEAPILTVTVNDDDEINN 338

Query: 185 SAIRYAIIGGNTQMQFSI---DSLSGDVSLVKTLDYE---QVRSYRLVIRAQDGGSPSRS 238
              +     G    +F++   +  +G + +V+ LD+E   Q+  +R  I+  D    + +
Sbjct: 339 FQYKIIESSGYGADKFAMIKNNDGTGSLRVVQPLDFEDPMQINGFRFRIQVTDNEGINDT 398

Query: 239 NT-----TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293
           +      + +++ ++D+NDN PRF     +   SEN  +G ++V  +A D D+   +++T
Sbjct: 399 DKYHVDHSWVIVKLKDINDNTPRFRRPHMEAYTSENDEVGKTLVSFKAIDIDKAGKSKIT 458

Query: 294 YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353
           Y M ++         I+ +   G V    QLDRE  +KY L + A D G PPR+ATAT  
Sbjct: 459 Y-MINRATDRKRQFSISDE---GTVTIQRQLDREAISKYNLEILAIDDGVPPRTATATLT 514

Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE---DNRLHYEI-----TG 405
                       F   +Y   L E+  P + ++ ++A D D+   +N   ++        
Sbjct: 515 VEVKDVNDNAPVFAE-EYRPILLENS-PASKIIEISAIDQDDRRMENGPPFQFRMDPDAD 572

Query: 406 GNTRGRFSITSQN-GRGLITVAQPLDFKQE--RRYVLTVSATDSG--GRSDTAMVQINIT 460
              R  F +   N G G+  V+    F +E  ++Y + +   DSG   ++ T+ + + I 
Sbjct: 573 DVIRTSFKVEQNNKGDGMAVVSSLRSFDREYRKQYEIPIVIKDSGNPAQTGTSTLTVTIG 632

Query: 461 DANN 464
           D N+
Sbjct: 633 DVND 636



 Score =  110 bits (265), Expect = 5e-22
 Identities = 138/598 (23%), Positives = 245/598 (40%), Gaps = 54/598 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSG--TTVLTLKATDQDIGKNAEVEYTIELVTAD 68
           +NV D ND+ PVFE   Y   + E    G    V+ + A+D D+ + + + Y +     D
Sbjct: 63  VNVKDVNDNPPVFERSSYRTQITEEDDRGLPKRVMRVTASDADVERPSNIIYFLTGPGID 122

Query: 69  TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
             NP ++              F I+  +G +     L+R+      +            +
Sbjct: 123 IENPSESN-------------FDINKATGEIFVLKPLNRDPPHGRPLWKFTVFAQDEGGE 169

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKA---TDADVGANS 185
            L     + + + D NDN P F +  Y  +V E+ +V     +  IKA    D D G ++
Sbjct: 170 GLVGFTEVQIKLKDINDNAPSFPQGIYYGNVTENGTV--GMYVMTIKAQDNDDVDEGTHA 227

Query: 186 AIRYAIIGGNTQMQ--FSIDSLSGDVSLVKT----LDYEQVRSYRLVIRAQDGGSPSRSN 239
            I Y+I     + +    I  ++ D  ++ T    LD E+   Y L I A DGG    + 
Sbjct: 228 KIVYSIEKNAIEEETGLPIFDINPDTGVITTAVCCLDREKTPDYSLQIVATDGGGLKGTG 287

Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSE---NVPIGYSIVRVQAYDADEGVNAELTYTM 296
           T    I ++D+ND  P F    +   V E   N+     I+ V   D DE +N      +
Sbjct: 288 TAS--IKVKDLNDMPPHFTKDEWFVEVEETDGNILPEAPILTVTVNDDDE-INNFQYKII 344

Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA-----KYQLLVTATDG---GDPPRSA 348
               Y  +    I  +  +G +     LD E        ++++ VT  +G    D     
Sbjct: 345 ESSGYGADKFAMIKNNDGTGSLRVVQPLDFEDPMQINGFRFRIQVTDNEGINDTDKYHVD 404

Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGG 406
            +               F     E   +E++  G  +V+  A D D+   +++ Y I   
Sbjct: 405 HSWVIVKLKDINDNTPRFRRPHMEAYTSENDEVGKTLVSFKAIDIDKAGKSKITYMINRA 464

Query: 407 NTRGR-FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDAN 463
             R R FSI+ +   G +T+ + LD +   +Y L + A D G   R+ TA + + + D N
Sbjct: 465 TDRKRQFSISDE---GTVTIQRQLDREAISKYNLEILAIDDGVPPRTATATLTVEVKDVN 521

Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD---VGINAQITYSLSSEISNE-AVAH 519
           + APVF    Y   + E++P  + ++ +SA D D   +       + +  +  +    + 
Sbjct: 522 DNAPVFAE-EYRPILLENSP-ASKIIEISAIDQDDRRMENGPPFQFRMDPDADDVIRTSF 579

Query: 520 HDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577
             +Q         +++ +  DRE    Y + +  +D G P+ + T+ + +++ DVNDN
Sbjct: 580 KVEQNNKGDGMAVVSSLRSFDREYRKQYEIPIVIKDSGNPAQTGTSTLTVTIGDVNDN 637



 Score = 89.0 bits (211), Expect = 2e-15
 Identities = 87/321 (27%), Positives = 134/321 (41%), Gaps = 27/321 (8%)

Query: 138 VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG-NT 196
           V + D NDN P+F          E+  V     +   KA D D    S I Y I    + 
Sbjct: 410 VKLKDINDNTPRFRRPHMEAYTSENDEV--GKTLVSFKAIDIDKAGKSKITYMINRATDR 467

Query: 197 QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256
           + QFSI    G V++ + LD E +  Y L I A D G P R+ T  L + ++DVNDNAP 
Sbjct: 468 KRQFSISD-EGTVTIQRQLDREAISKYNLEILAIDDGVPPRTATATLTVEVKDVNDNAPV 526

Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEG--VNAELTYTMTDKDYTGNVDLPITIDPR 314
           F    ++  + EN P    I+ + A D D+    N        D D    +     ++  
Sbjct: 527 F-AEEYRPILLENSPAS-KIIEISAIDQDDRRMENGPPFQFRMDPDADDVIRTSFKVEQN 584

Query: 315 S---GWVYTSG--QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
           +   G    S     DRE + +Y++ +   D G+P ++ T+T                PG
Sbjct: 585 NKGDGMAVVSSLRSFDREYRKQYEIPIVIKDSGNPAQTGTST--LTVTIGDVNDNIMQPG 642

Query: 370 QYEVEL--AEDEPPGTPVVTLTATDADE---DNRLHYEITGGNTRGRFSITSQNGRGLIT 424
             EV +   + + P TP+  +   D D+    ++L Y     N R +   TS    G++T
Sbjct: 643 SKEVVVYNYQGQAPDTPIGRVFVNDLDDWDTSDKLFYWDELENPRFKLDDTS----GMVT 698

Query: 425 VAQPLDFKQERRYVLTVSATD 445
           + +     +E RY L     D
Sbjct: 699 MRRG---AREGRYKLRFKIYD 716


>UniRef50_Q96JQ0 Cluster: Protocadherin-16 precursor; n=12;
           Amniota|Rep: Protocadherin-16 precursor - Homo sapiens
           (Human)
          Length = 3298

 Score =  314 bits (770), Expect = 3e-83
 Identities = 253/819 (30%), Positives = 377/819 (46%), Gaps = 52/819 (6%)

Query: 92  IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151
           ID  SG + T   LDRE+  RY       D A         T  + V + D ND+ P F 
Sbjct: 94  IDEHSGVVRTARVLDREQRDRYRFTAVTPDGA---------TVEVTVRVADINDHAPAFP 144

Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD--- 208
           +    + V E  +      +    A DAD G      YA+ G      F +++  G    
Sbjct: 145 QARAALQVPEHTAFGTRYPLEP--ARDADAGRLGTQGYALSGDGAGETFRLETRPGPDGT 202

Query: 209 --VSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
               LV T  LD E    Y L + A DGGSP R     L + + D+ND+AP F  S +  
Sbjct: 203 PVPELVVTGELDRENRSHYMLQLEAYDGGSPPRRAQALLDVTLLDINDHAPAFNQSRYHA 262

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
            VSE++  G  +++V A DAD GVN  +TY +  +   G  D P +ID  +G +     L
Sbjct: 263 VVSESLAPGSPVLQVFASDADAGVNGAVTYEINRRQSEG--DGPFSIDAHTGLLQLERPL 320

Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX----XXXXXFMPGQYEVELAEDEP 380
           D E +  ++L+V A DGG  P   +A                   F+      +++E  P
Sbjct: 321 DFEQRRVHELVVQARDGGAHPELGSAFVTVHVRDANDNQPSMTVIFLSADGSPQVSEAAP 380

Query: 381 PGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG-RGLITVAQPLDFKQERRYVL 439
           PG  V  ++ +D D+ +  H  ++     G F++++Q+    L+ VA+ LD ++   Y L
Sbjct: 381 PGQLVARISVSDPDDGDFAHVNVSLEGGEGHFALSTQDSVIYLVCVARRLDREERDAYNL 440

Query: 440 TVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI-GTTVLVVSATD 495
            V+ATDSG    R++ A V +++TD N+ AP F+   Y      +  + G+ V+ V+A D
Sbjct: 441 RVTATDSGSPPLRAEAAFV-LHVTDVNDNAPAFDRQLYRPEPLPEVALPGSFVVRVTARD 499

Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555
            D G N Q+TYSL       A   H   F I+P +G ITT   LD E      L V A D
Sbjct: 500 PDQGTNGQVTYSL-------APGAHTHWFSIDPTSGIITTAASLDYELEPQPQLIVVATD 552

Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615
           GG+P L+ +  V +++ DVNDNEP F++  Y A++ E    GT   QV ATDAD G  G 
Sbjct: 553 GGLPPLASSATVSVALQDVNDNEPQFQRTFYNASLPEGTQPGTCFLQVTATDADSGPFGL 612

Query: 616 IHYELDPKDREEGS--FVIDPASGVIRTNKALDR-ESVATHDLKAVAIDGGTPPQSSTVI 672
           + Y L       GS  F ID  SG + T + LDR +  ++ D    A+DGG     S V 
Sbjct: 613 LSYSLGAGLGSSGSPPFRIDAHSGDVCTTRTLDRDQGPSSFDFTVTAVDGG--GLKSMVY 670

Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732
           V + + D ND+PP F        IS  SP GT +  +RAHDPD+G +  + Y I  G+  
Sbjct: 671 VKVFLSDENDNPPQFYPREYAASISAQSPPGTAVLRLRAHDPDQGSHGRLSYHILAGNSP 730

Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVND 789
             F+L+ + G     L+T+            +L I A            RV+I +     
Sbjct: 731 PLFTLDEQSG-----LLTVAWPLARRANSVVQLEIGAEDGGGLQAEPSARVDISIVPGTP 785

Query: 790 NAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD-ADVTDKLQYRILSGNNANLILLNETTGS 848
             P+ +  Q +F+  +D  P    G V A++       +   +  G+   L  L+  +G 
Sbjct: 786 TPPIFEQLQYVFSVPEDVAPGTSVGIVQAHNPPGRLAPVTLSLSGGDPRGLFSLDAVSGL 845

Query: 849 M-TLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886
           + TL P     +  +  +EV    GV    A+ ++ V L
Sbjct: 846 LQTLRPLDRELLGPVLELEVRAGSGVPPAFAVARVRVLL 884



 Score =  310 bits (762), Expect = 3e-82
 Identities = 257/812 (31%), Positives = 391/812 (48%), Gaps = 82/812 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEAS------VREGASSGTTVLTLKATDQDIGKNAEVEYTIEL 64
            + VLD ND+SP F      A       V +    GT V TL+A D D G+N  + YT+  
Sbjct: 1199 VAVLDLNDNSPTFLQASGAAGGGLPIQVPDRVPPGTLVTTLQAKDPDEGENGTILYTLT- 1257

Query: 65   VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS 124
                   P               ++F +   SG LLT A L R +   Y + + A DQ S
Sbjct: 1258 ------GPGS-------------ELFSLHPHSGELLTAAPLIRAERPHYVLTLSAHDQGS 1298

Query: 125  PVSDRLSSTATIHVNIIDD---NDNYPQFSEKTYTVSVDEDISVT------DNPVIAKIK 175
            P     S++  + V ++      +  P  +E+     V   ++VT         ++  + 
Sbjct: 1299 PPR---SASLQLLVQVLPSARLAEPPPDLAERDPAAPVPVVLTVTAAEGLRPGSLLGSVA 1355

Query: 176  ATD-ADVGANSAIRYAIIGG-NTQMQFSIDSLSGDVSLVKTLDYEQVRSYR-LVIRAQ-D 231
            A + A VG   A+ Y ++GG + +  F++D+ SG + L + LD+E    +R L +RA+  
Sbjct: 1356 APEPAGVG---ALTYTLVGGADPEGTFALDAASGRLYLARPLDFEAGPPWRALTVRAEGP 1412

Query: 232  GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNA 290
            GG+ +R    Q  + ++D N++AP F       ++ EN   G ++   +A DAD  G N+
Sbjct: 1413 GGAGARLLRVQ--VQVQDENEHAPAFARDPLALALPENPEPGAALYTFRASDADGPGPNS 1470

Query: 291  ELTYTMTDKDYTGNVDLP-ITIDPRSGWVYTSGQLDRETQAKYQLLVTATD--GGDPPRS 347
            ++ Y +  ++      +P + +D R+G +     LDRET     LLV ATD       R 
Sbjct: 1471 DVRYRLLRQE----PPVPALRLDARTGALSAPRGLDRETTPALLLLVEATDRPANASRRR 1526

Query: 348  ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITG 405
            A                        V L ED+PPG   + + A D D  E  R+ Y +  
Sbjct: 1527 AARVSARVFVTDENDNAPVFASPSRVRLPEDQPPGPAALHVVARDPDLGEAARVSYRLAS 1586

Query: 406  GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDAN 463
            G   G F + S    G ++V +PLD +Q   +VLTV A+D G   RS T ++ +++ D N
Sbjct: 1587 GGD-GHFRLHSST--GALSVVRPLDREQRAEHVLTVVASDHGSPPRSATQVLTVSVADVN 1643

Query: 464  NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523
            + AP F+   Y+  + E+ P GT++L + ATD DVG N Q+TY     +S+E+       
Sbjct: 1644 DEAPTFQQQEYSVLLRENNPPGTSLLTLRATDPDVGANGQVTY---GGVSSES------- 1693

Query: 524  FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583
            F ++P TG +TT + LDRE      LTV A+D G P       V ++V D ND+ P F  
Sbjct: 1694 FSLDPDTGVLTTLRALDREEQEEINLTVYAQDRGSPPQLTHVTVRVAVEDENDHAPTFGS 1753

Query: 584  QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK 643
               +  + E     T ++ + A+D DVG NG++ Y +   D   G+FV+D ASG   T +
Sbjct: 1754 AHLSLEVPEGQDPQT-LTMLRASDPDVGANGQLQYRILDGD-PSGAFVLDLASGEFGTMR 1811

Query: 644  ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703
             LDRE      L+  A DGG P  S+T+++ + + D ND  P F     +  + E+ P G
Sbjct: 1812 PLDREVEPAFQLRIEARDGGQPALSATLLLTVTVLDANDHAPAFPVPAYSVEVPEDVPAG 1871

Query: 704  TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES-PRKK 762
            T + +++AHDPD G N  V Y + G   + +F LE   G    EL T   LD E  P   
Sbjct: 1872 TLLLQLQAHDPDAGANGHVTYYL-GAGTAGAFLLEPSSG----ELRTAAALDREQCPSYT 1926

Query: 763  YEL--VIRAASPPLWNDVRVEILVTDVNDNAP 792
            + +  V  AA+ PL   V V I V DVND+AP
Sbjct: 1927 FSVSAVDGAAAGPLSTTVSVTITVRDVNDHAP 1958



 Score =  305 bits (749), Expect = 1e-80
 Identities = 241/793 (30%), Positives = 359/793 (45%), Gaps = 66/793 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            ++V D ND +P F+ Q+Y   +RE    GT++LTL+ATD D+G N +V Y          
Sbjct: 1637 VSVADVNDEAPTFQQQEYSVLLRENNPPGTSLLTLRATDPDVGANGQVTY---------- 1686

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                             + F +D  +G L T  +LDRE+     + V A D+ SP     
Sbjct: 1687 ------------GGVSSESFSLDPDTGVLTTLRALDREEQEEINLTVYAQDRGSPPQ--- 1731

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             +  T+ V + D+ND+ P F     ++ V E     D   +  ++A+D DVGAN  ++Y 
Sbjct: 1732 LTHVTVRVAVEDENDHAPTFGSAHLSLEVPEG---QDPQTLTMLRASDPDVGANGQLQYR 1788

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I+ G+    F +D  SG+   ++ LD E   +++L I A+DGG P+ S T  L + + D 
Sbjct: 1789 ILDGDPSGAFVLDLASGEFGTMRPLDREVEPAFQLRIEARDGGQPALSATLLLTVTVLDA 1848

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            ND+AP F    +   V E+VP G  ++++QA+D D G N  +TY +      G       
Sbjct: 1849 NDHAPAFPVPAYSVEVPEDVPAGTLLLQLQAHDPDAGANGHVTYYLG----AGTAG-AFL 1903

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSATATXXXXXXXXXXXXXXFMPG 369
            ++P SG + T+  LDRE    Y   V+A DG    P S T +              F   
Sbjct: 1904 LEPSSGELRTAAALDREQCPSYTFSVSAVDGAAAGPLSTTVSVTITVRDVNDHAPTFPTS 1963

Query: 370  QYEVELAEDEP----PGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLI 423
               + L    P    P   + TL A D D   +  + Y + G    G    T  +  G I
Sbjct: 1964 PLRLRLPRPGPSFSTPTLALATLRAEDRDAGANASILYRLAGTPPPG---TTVDSYTGEI 2020

Query: 424  TVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
             VA+       R  VL + ATD G   RS T ++ + +       P F  A   A++ E+
Sbjct: 2021 RVARSPVALGPRDRVLFIVATDLGRPARSATGVIIVGLQGEAERGPRFPRASSEATIREN 2080

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL--L 539
            AP GT ++   A  +  G N  ITYS+ S   NE        F I P TGAIT      L
Sbjct: 2081 APPGTPIVSPRAVHAG-GTNGPITYSILS--GNE-----KGTFSIQPSTGAITVRSAEGL 2132

Query: 540  DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
            D E      L + A  GG  +    T + +++ D NDN P F +  Y A + E   +   
Sbjct: 2133 DFEVSPRLRLVLQAESGGAFAF---TVLTLTLQDANDNAPRFLRPHYVAFLPESRPLEGP 2189

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
            + QV A D D G  G+I Y L       G F +DP +G I T   LDRE  A   L  +A
Sbjct: 2190 LLQVEADDLDQGSGGQISYSLAASQPARGLFHVDPTTGTITTTAILDREIWAETRLVLMA 2249

Query: 660  IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
             D G+P    +  + + + D ND+ P          +SE++ +G+ I ++  +D D GP 
Sbjct: 2250 TDRGSPALVGSATLTVMVIDTNDNRPTIPQP-WELRVSEDALLGSEIAQVTGNDVDSGP- 2307

Query: 720  AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR 779
             V+ Y +      + FS+    G     +     LD+E    +Y+L + A   P      
Sbjct: 2308 -VLWYVLSPSGPQDPFSV----GRYGGRVSLTGPLDFEQ-CDRYQLQLLAHDGPHEGRAN 2361

Query: 780  VEILVTDVNDNAP 792
            + +LV DVNDNAP
Sbjct: 2362 LTVLVEDVNDNAP 2374



 Score =  300 bits (737), Expect = 3e-79
 Identities = 234/786 (29%), Positives = 361/786 (45%), Gaps = 46/786 (5%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + +LD NDH+P F   +Y A V E  + G+ VL + A+D D G N  V Y I    ++  
Sbjct: 243 VTLLDINDHAPAFNQSRYHAVVSESLAPGSPVLQVFASDADAGVNGAVTYEINRRQSEGD 302

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            P                 F ID  +G L     LD E+   + ++V+A D  +   +  
Sbjct: 303 GP-----------------FSIDAHTGLLQLERPLDFEQRRVHELVVQARDGGAH-PELG 344

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP--VIAKIKATDADVGANSAIR 188
           S+  T+HV   D NDN P  +    +      +S    P  ++A+I  +D D G  + + 
Sbjct: 345 SAFVTVHVR--DANDNQPSMTVIFLSADGSPQVSEAAPPGQLVARISVSDPDDGDFAHVN 402

Query: 189 YAIIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            ++ GG      S  DS+   V + + LD E+  +Y L + A D GSP        ++++
Sbjct: 403 VSLEGGEGHFALSTQDSVIYLVCVARRLDREERDAYNLRVTATDSGSPPLRAEAAFVLHV 462

Query: 248 RDVNDNAPRFYTSLFQ-ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            DVNDNAP F   L++ E + E    G  +VRV A D D+G N ++TY++    +T    
Sbjct: 463 TDVNDNAPAFDRQLYRPEPLPEVALPGSFVVRVTARDPDQGTNGQVTYSLAPGAHTH--- 519

Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
              +IDP SG + T+  LD E + + QL+V ATDGG PP +++AT              F
Sbjct: 520 -WFSIDPTSGIITTAASLDYELEPQPQLIVVATDGGLPPLASSATVSVALQDVNDNEPQF 578

Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGG-NTRGRFSITSQNGRGLI 423
               Y   L E   PGT  + +TATDAD      L Y +  G  + G          G +
Sbjct: 579 QRTFYNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLGAGLGSSGSPPFRIDAHSGDV 638

Query: 424 TVAQPLDFKQ-ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
              + LD  Q    +  TV+A D GG      V++ ++D N+  P F    Y AS+   +
Sbjct: 639 CTTRTLDRDQGPSSFDFTVTAVDGGGLKSMVYVKVFLSDENDNPPQFYPREYAASISAQS 698

Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
           P GT VL + A D D G + +++Y +          +    F ++ Q+G +T    L R 
Sbjct: 699 PPGTAVLRLRAHDPDQGSHGRLSYHI-------LAGNSPPLFTLDEQSGLLTVAWPLARR 751

Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
             S   L + A DGG      +  V+IS+V      P+F+Q  Y  ++ ED   GTSV  
Sbjct: 752 ANSVVQLEIGAEDGGGLQAEPSARVDISIVPGTPTPPIFEQLQYVFSVPEDVAPGTSVGI 811

Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
           V A +   G    +   L   D   G F +D  SG+++T + LDRE +       V    
Sbjct: 812 VQAHNPP-GRLAPVTLSLSGGD-PRGLFSLDAVSGLLQTLRPLDRELLGPVLELEVRAGS 869

Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
           G PP  +   V + ++D+ND+ P F +   T  +  N+  GT I  +RA DPD G N+ V
Sbjct: 870 GVPPAFAVARVRVLLDDVNDNSPAFPAPEDTVLLPPNTAPGTPIYTLRALDPDSGVNSRV 929

Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR-AASPPLWNDVRVE 781
            +++  G    +F+++   G     L+  +      P  + EL  R   SPP  +  R+ 
Sbjct: 930 TFTLLAG-GGGAFTVDPTTG--HVRLMRPLG-PSGGPAHELELEARDGGSPPRTSHFRLR 985

Query: 782 ILVTDV 787
           ++V DV
Sbjct: 986 VVVQDV 991



 Score =  292 bits (716), Expect = 1e-76
 Identities = 257/913 (28%), Positives = 420/913 (46%), Gaps = 87/913 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASV-REGASSGTTVL---TLKATDQDIGKNAEVEYTIELVT 66
            I V D NDH+P F        + R G S  T  L   TL+A D+D G NA + Y +    
Sbjct: 1948 ITVRDVNDHAPTFPTSPLRLRLPRPGPSFSTPTLALATLRAEDRDAGANASILYRL---- 2003

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
            A T  P                  R+  RS   L      R++V    + + ATD   P 
Sbjct: 2004 AGTPPPGTTVDSYTGE-------IRV-ARSPVALG----PRDRV----LFIVATDLGRPA 2047

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
                S+T  I V +  + +  P+F   +   ++ E+ +    P+++  +A  A  G N  
Sbjct: 2048 R---SATGVIIVGLQGEAERGPRFPRASSEATIREN-APPGTPIVSP-RAVHAG-GTNGP 2101

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSL--VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
            I Y+I+ GN +  FSI   +G +++   + LD+E     RLV++A+ GG+ +    T L 
Sbjct: 2102 ITYSILSGNEKGTFSIQPSTGAITVRSAEGLDFEVSPRLRLVLQAESGGAFA---FTVLT 2158

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
            + ++D NDNAPRF    +   + E+ P+   +++V+A D D+G   +++Y++        
Sbjct: 2159 LTLQDANDNAPRFLRPHYVAFLPESRPLEGPLLQVEADDLDQGSGGQISYSLAASQPARG 2218

Query: 305  VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
            +     +DP +G + T+  LDRE  A+ +L++ ATD G P    +AT             
Sbjct: 2219 L---FHVDPTTGTITTTAILDREIWAETRLVLMATDRGSPALVGSATLTVMVIDTNDNRP 2275

Query: 365  XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLIT 424
              +P  +E+ ++ED   G+ +  +T  D D    L Y ++    +  FS+    GR  ++
Sbjct: 2276 T-IPQPWELRVSEDALLGSEIAQVTGNDVDSGPVLWYVLSPSGPQDPFSVGRYGGR--VS 2332

Query: 425  VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
            +  PLDF+Q  RY L + A D G     A + + + D N+ AP F  + Y   + E  P 
Sbjct: 2333 LTGPLDFEQCDRYQLQLLAHD-GPHEGRANLTVLVEDVNDNAPAFSQSLYQVMLLEHTPP 2391

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT---NKLLDR 541
            G+ +L VSATD D G N  I+Y L+S             F ++P  G + T      L  
Sbjct: 2392 GSAILSVSATDRDSGANGHISYHLASPADG---------FSVDPNNGTLFTIVGTVALGH 2442

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
            +      + + ARD G P  +    V + + D ND+ P F    Y   + ED   G+++ 
Sbjct: 2443 DGSGAVDVVLEARDHGAPGRAARATVHVQLQDQNDHAPSFTLSHYRVAVTEDLPPGSTLL 2502

Query: 602  QVGATDAD-------------VGLNGRIHYELDPKDREEG-SFVIDP-ASGVIRTNKALD 646
             + ATDAD              G  GR+ ++L+P+  E G S    P A G +   + LD
Sbjct: 2503 TLEATDADGSRSHAAVDYSIISGNWGRV-FQLEPRLAEAGESAGPGPRALGCLVLLEPLD 2561

Query: 647  RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706
             ES+  ++L   A D G PPQSS V V + + D+ND+PPVF        + E++P+G  +
Sbjct: 2562 FESLTQYNLTVAAADRGQPPQSSVVPVTVTVLDVNDNPPVFTRASYRVTVPEDTPVGAEL 2621

Query: 707  GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV 766
              + A D D GP+ +V +++  GD S  F L+   G+    L   +D + ++   +++LV
Sbjct: 2622 LHVEASDADPGPHGLVRFTVSSGDPSGLFELDESSGT--LRLAHALDCETQA---RHQLV 2676

Query: 767  IRAASP--PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDAD- 822
            ++AA P    +    V I V DVND+ P      ++  +  +  P G     + A D D 
Sbjct: 2677 VQAADPAGAHFALAPVTIEVQDVNDHGPAF-PLNLLSTSVAENQPPGTLVTTLHAIDGDA 2735

Query: 823  -VTDKLQYRILSG----NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIK 877
                +L+Y +L             LN +TG +      +    +   + V   D  N + 
Sbjct: 2736 GAFGRLRYSLLEAGPGPEGREAFALNSSTGELRARVPFDYEHTESFRLLVGAADAGN-LS 2794

Query: 878  AMMQLSVRLITEE 890
            A + +SV L+T E
Sbjct: 2795 ASVTVSV-LVTGE 2806



 Score =  291 bits (713), Expect = 2e-76
 Identities = 259/891 (29%), Positives = 401/891 (45%), Gaps = 76/891 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++++L+ N+HSP         +V E    GT+V  + ATD+D G N  + Y+++ ++ D+
Sbjct: 1092 RVSILNQNEHSPRLSEDPTFLAVAENQPPGTSVGRVFATDRDSGPNGRLTYSLQQLSEDS 1151

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                                FRI  ++G + T  +LDRE+ + Y +LV+  D  SP    
Sbjct: 1152 ------------------KAFRIHPQTGEVTTLQTLDREQQSSYQLLVQVQDGGSPPR-- 1191

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDN----PVIAKIKATDADVGANS 185
             S+T T+HV ++D NDN P F + +        I V D      ++  ++A D D G N 
Sbjct: 1192 -STTGTVHVAVLDLNDNSPTFLQASGAAGGGLPIQVPDRVPPGTLVTTLQAKDPDEGENG 1250

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
             I Y + G  +++ FS+   SG++     L   +   Y L + A D GSP RS + QLL+
Sbjct: 1251 TILYTLTGPGSEL-FSLHPHSGELLTAAPLIRAERPHYVLTLSAHDQGSPPRSASLQLLV 1309

Query: 246  NIR----------DVNDNAPRFYTSL-FQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294
             +           D+ +  P     +    + +E +  G S++   A     GV A LTY
Sbjct: 1310 QVLPSARLAEPPPDLAERDPAAPVPVVLTVTAAEGLRPG-SLLGSVAAPEPAGVGA-LTY 1367

Query: 295  TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354
            T+       + +    +D  SG +Y +  LD E    ++ L    +G     +       
Sbjct: 1368 TLVGG---ADPEGTFALDAASGRLYLARPLDFEAGPPWRALTVRAEGPGGAGARLLRVQV 1424

Query: 355  XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGR 411
                       F      + L E+  PG  + T  A+DAD    ++ + Y +        
Sbjct: 1425 QVQDENEHAPAFARDPLALALPENPEPGAALYTFRASDADGPGPNSDVRYRLLRQEPPVP 1484

Query: 412  FSITSQNGRGLITVAQPLDFKQERRYVLTVSATD-----SGGRSDTAMVQINITDANNYA 466
             ++      G ++  + LD +     +L V ATD     S  R+     ++ +TD N+ A
Sbjct: 1485 -ALRLDARTGALSAPRGLDRETTPALLLLVEATDRPANASRRRAARVSARVFVTDENDNA 1543

Query: 467  PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
            PVF + P    + ED P G   L V A D D+G  A+++Y L+S          D  F +
Sbjct: 1544 PVFAS-PSRVRLPEDQPPGPAALHVVARDPDLGEAARVSYRLASG--------GDGHFRL 1594

Query: 527  NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586
            +  TGA++  + LDRE  + ++LTV A D G P  S T  + +SV DVND  P F+QQ Y
Sbjct: 1595 HSSTGALSVVRPLDREQRAEHVLTVVASDHGSPPRSATQVLTVSVADVNDEAPTFQQQEY 1654

Query: 587  TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646
            +  + E+   GTS+  + ATD DVG NG++ Y          SF +DP +GV+ T +ALD
Sbjct: 1655 SVLLRENNPPGTSLLTLRATDPDVGANGQVTY----GGVSSESFSLDPDTGVLTTLRALD 1710

Query: 647  RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706
            RE     +L   A D G+PPQ + V V + +ED ND  P F S  L+  + E      T+
Sbjct: 1711 REEQEEINLTVYAQDRGSPPQLTHVTVRVAVEDENDHAPTFGSAHLSLEVPEGQD-PQTL 1769

Query: 707  GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPRKKYEL 765
              +RA DPD G N  + Y I  GD S +F L+   G    E  TM  LD E  P  +  +
Sbjct: 1770 TMLRASDPDVGANGQLQYRILDGDPSGAFVLDLASG----EFGTMRPLDREVEPAFQLRI 1825

Query: 766  VIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDAD- 822
              R    P L   + + + V D ND+AP            +D  P G    ++ A+D D 
Sbjct: 1826 EARDGGQPALSATLLLTVTVLDANDHAPAFPVPAYSVEVPED-VPAGTLLLQLQAHDPDA 1884

Query: 823  -VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
                 + Y  L    A   LL  ++G +  +  L+       T  VS  DG
Sbjct: 1885 GANGHVTY-YLGAGTAGAFLLEPSSGELRTAAALDREQCPSYTFSVSAVDG 1934



 Score =  289 bits (709), Expect = 7e-76
 Identities = 225/742 (30%), Positives = 345/742 (46%), Gaps = 74/742 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + + D ND++P F    Y A + E       +L ++A D D G   ++ Y++        
Sbjct: 2159 LTLQDANDNAPRFLRPHYVAFLPESRPLEGPLLQVEADDLDQGSGGQISYSL-------- 2210

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                            + +F +D  +G + T A LDRE  A   +++ ATD+ SP    L
Sbjct: 2211 ----------AASQPARGLFHVDPTTGTITTTAILDREIWAETRLVLMATDRGSPA---L 2257

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
              +AT+ V +ID NDN P   +  + + V ED  +     IA++   D D G    + Y 
Sbjct: 2258 VGSATLTVMVIDTNDNRPTIPQP-WELRVSEDALLGSE--IAQVTGNDVDSGP--VLWYV 2312

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            +     Q  FS+    G VSL   LD+EQ   Y+L + A DG    R+N T L   + DV
Sbjct: 2313 LSPSGPQDPFSVGRYGGRVSLTGPLDFEQCDRYQLQLLAHDGPHEGRANLTVL---VEDV 2369

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDNAP F  SL+Q  + E+ P G +I+ V A D D G N  ++Y +         D   +
Sbjct: 2370 NDNAPAFSQSLYQVMLLEHTPPGSAILSVSATDRDSGANGHISYHLASP-----AD-GFS 2423

Query: 311  IDPRSGWVYT---SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
            +DP +G ++T   +  L  +      +++ A D G P R+A AT              F 
Sbjct: 2424 VDPNNGTLFTIVGTVALGHDGSGAVDVVLEARDHGAPGRAARATVHVQLQDQNDHAPSFT 2483

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADEDNRLH----YEITGGNTRGRFSITSQ------ 417
               Y V + ED PPG+ ++TL ATDAD  +R H    Y I  GN    F +  +      
Sbjct: 2484 LSHYRVAVTEDLPPGSTLLTLEATDAD-GSRSHAAVDYSIISGNWGRVFQLEPRLAEAGE 2542

Query: 418  ------NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVF 469
                     G + + +PLDF+   +Y LTV+A D G    +++V + +T  D N+  PVF
Sbjct: 2543 SAGPGPRALGCLVLLEPLDFESLTQYNLTVAAADRGQPPQSSVVPVTVTVLDVNDNPPVF 2602

Query: 470  ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
              A Y  +V ED P+G  +L V A+D+D G +  + +++SS             F ++  
Sbjct: 2603 TRASYRVTVPEDTPVGAELLHVEASDADPGPHGLVRFTVSS-------GDPSGLFELDES 2655

Query: 530  TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589
            +G +     LD ET + + L V A D      +    V I V DVND+ P F   L + +
Sbjct: 2656 SGTLRLAHALDCETQARHQLVVQAADPAGAHFA-LAPVTIEVQDVNDHGPAFPLNLLSTS 2714

Query: 590  IMEDALVGTSVSQVGATDADVGLNGRIHYEL-----DPKDREEGSFVIDPASGVIRTNKA 644
            + E+   GT V+ + A D D G  GR+ Y L      P+ RE  +F ++ ++G +R    
Sbjct: 2715 VAENQPPGTLVTTLHAIDGDAGAFGRLRYSLLEAGPGPEGRE--AFALNSSTGELRARVP 2772

Query: 645  LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
             D E   +  L   A D G    S TV V +  ED  D  PVF +    F + E +  G 
Sbjct: 2773 FDYEHTESFRLLVGAADAGNLSASVTVSVLVTGEDEYD--PVFLAPAFHFQVPEGARRGH 2830

Query: 705  TIGEIRAHDPDEGPNAVVHYSI 726
            ++G ++A D D G + +V YS+
Sbjct: 2831 SLGHVQATDEDGGADGLVLYSL 2852



 Score =  284 bits (697), Expect = 2e-74
 Identities = 212/695 (30%), Positives = 314/695 (45%), Gaps = 29/695 (4%)

Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252
           G       +ID  SG V   + LD EQ   YR      DG       T ++ + + D+ND
Sbjct: 85  GSGVGTDLAIDEHSGVVRTARVLDREQRDRYRFTAVTPDGA------TVEVTVRVADIND 138

Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312
           +AP F  +     V E+   G       A DAD G      Y ++         L     
Sbjct: 139 HAPAFPQARAALQVPEHTAFGTRYPLEPARDADAGRLGTQGYALSGDGAGETFRLETRPG 198

Query: 313 PRSGWV---YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
           P    V     +G+LDRE ++ Y L + A DGG PPR A A               F   
Sbjct: 199 PDGTPVPELVVTGELDRENRSHYMLQLEAYDGGSPPRRAQALLDVTLLDINDHAPAFNQS 258

Query: 370 QYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
           +Y   ++E   PG+PV+ + A+DAD   +  + YEI    + G    +     GL+ + +
Sbjct: 259 RYHAVVSESLAPGSPVLQVFASDADAGVNGAVTYEINRRQSEGDGPFSIDAHTGLLQLER 318

Query: 428 PLDFKQERRYVLTVSATDSGGRSD--TAMVQINITDANNYAP----VFENAPYTASVFED 481
           PLDF+Q R + L V A D G   +  +A V +++ DAN+  P    +F +A  +  V E 
Sbjct: 319 PLDFEQRRVHELVVQARDGGAHPELGSAFVTVHVRDANDNQPSMTVIFLSADGSPQVSEA 378

Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
           AP G  V  +S +D D G  A +  SL     + A++  D    +      +   + LDR
Sbjct: 379 APPGQLVARISVSDPDDGDFAHVNVSLEGGEGHFALSTQDSVIYL------VCVARRLDR 432

Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN-IMEDALVGTSV 600
           E    Y L VTA D G P L       + V DVNDN P F +QLY    + E AL G+ V
Sbjct: 433 EERDAYNLRVTATDSGSPPLRAEAAFVLHVTDVNDNAPAFDRQLYRPEPLPEVALPGSFV 492

Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
            +V A D D G NG++ Y L P       F IDP SG+I T  +LD E      L  VA 
Sbjct: 493 VRVTARDPDQGTNGQVTYSLAPGAHTHW-FSIDPTSGIITTAASLDYELEPQPQLIVVAT 551

Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
           DGG PP +S+  V + ++D+ND+ P F+       + E +  GT   ++ A D D GP  
Sbjct: 552 DGGLPPLASSATVSVALQDVNDNEPQFQRTFYNASLPEGTQPGTCFLQVTATDADSGPFG 611

Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVR 779
           ++ YS+  G  S S S   R  +   ++ T   LD +     ++  + A     L + V 
Sbjct: 612 LLSYSLGAGLGS-SGSPPFRIDAHSGDVCTTRTLDRDQGPSSFDFTVTAVDGGGLKSMVY 670

Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGNNA 837
           V++ ++D NDN P     +   +      P     R+ A+D D     +L Y IL+GN+ 
Sbjct: 671 VKVFLSDENDNPPQFYPREYAASISAQSPPGTAVLRLRAHDPDQGSHGRLSYHILAGNSP 730

Query: 838 NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            L  L+E +G +T++  L      +  +E+   DG
Sbjct: 731 PLFTLDEQSGLLTVAWPLARRANSVVQLEIGAEDG 765



 Score =  281 bits (689), Expect = 2e-73
 Identities = 234/800 (29%), Positives = 366/800 (45%), Gaps = 68/800 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEAS-VREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++V D ND++P F+ Q Y    + E A  G+ V+ + A D D G N +V Y++    A T
Sbjct: 460  LHVTDVNDNAPAFDRQLYRPEPLPEVALPGSFVVRVTARDPDQGTNGQVTYSLA-PGAHT 518

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                                F ID  SG + T ASLD E   +  ++V ATD   P    
Sbjct: 519  ------------------HWFSIDPTSGIITTAASLDYELEPQPQLIVVATDGGLP---P 557

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            L+S+AT+ V + D NDN PQF    Y  S+ E           ++ ATDAD G    + Y
Sbjct: 558  LASSATVSVALQDVNDNEPQFQRTFYNASLPE--GTQPGTCFLQVTATDADSGPFGLLSY 615

Query: 190  AI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQ-VRSYRLVIRAQDGGSPSRSNTTQLLI 245
            ++   +G +    F ID+ SGDV   +TLD +Q   S+   + A DGG     +   + +
Sbjct: 616  SLGAGLGSSGSPPFRIDAHSGDVCTTRTLDRDQGPSSFDFTVTAVDGG--GLKSMVYVKV 673

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
             + D NDN P+FY   +  S+S   P G +++R++A+D D+G +  L+Y +      GN 
Sbjct: 674  FLSDENDNPPQFYPREYAASISAQSPPGTAVLRLRAHDPDQGSHGRLSYHI----LAGNS 729

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
                T+D +SG +  +  L R   +  QL + A DGG      +A               
Sbjct: 730  PPLFTLDEQSGLLTVAWPLARRANSVVQLEIGAEDGGGLQAEPSARVDISIVPGTPTPPI 789

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTA-TDADEDNRLHYEITGGNTRGRFSITSQNGRGLIT 424
            F   QY   + ED  PGT V  + A         +   ++GG+ RG FS+ + +  GL+ 
Sbjct: 790  FEQLQYVFSVPEDVAPGTSVGIVQAHNPPGRLAPVTLSLSGGDPRGLFSLDAVS--GLLQ 847

Query: 425  VAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFED 481
              +PLD ++    VL +      G       A V++ + D N+ +P F     T  +  +
Sbjct: 848  TLRPLD-RELLGPVLELEVRAGSGVPPAFAVARVRVLLDDVNDNSPAFPAPEDTVLLPPN 906

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
               GT +  + A D D G+N+++T++L        +A     F ++P TG +   + L  
Sbjct: 907  TAPGTPIYTLRALDPDSGVNSRVTFTL--------LAGGGGAFTVDPTTGHVRLMRPLGP 958

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN--EPVFKQQLYTANIMEDALVGTS 599
                 + L + ARDGG P  +    + + V DV      P F    Y  ++      GT 
Sbjct: 959  SGGPAHELELEARDGGSPPRTSHFRLRVVVQDVGTRGLAPRFNSPTYRVDLPSGTTAGTQ 1018

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
            V QV A   D    G I Y L   +     F ++P SG +    ALDRE+   + LK +A
Sbjct: 1019 VLQVQAQAPD---GGPITYHL-AAEGASSPFGLEPQSGWLWVRAALDREAQELYILKVMA 1074

Query: 660  IDGGTP---PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
            + G       Q+ T  V + I + N+  P    D     ++EN P GT++G + A D D 
Sbjct: 1075 VSGSKAELGQQTGTATVRVSILNQNEHSPRLSEDPTFLAVAENQPPGTSVGRVFATDRDS 1134

Query: 717  GPNAVVHYSIKG-GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR---AASP 772
            GPN  + YS++   +DS +F +  + G    E+ T+  LD E  +  Y+L+++     SP
Sbjct: 1135 GPNGRLTYSLQQLSEDSKAFRIHPQTG----EVTTLQTLDREQ-QSSYQLLVQVQDGGSP 1189

Query: 773  PLWNDVRVEILVTDVNDNAP 792
            P      V + V D+NDN+P
Sbjct: 1190 PRSTTGTVHVAVLDLNDNSP 1209



 Score =  275 bits (674), Expect = 1e-71
 Identities = 226/785 (28%), Positives = 357/785 (45%), Gaps = 45/785 (5%)

Query: 105  LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS 164
            LDRE+   Y + V ATD  SP    L + A   +++ D NDN P F  + Y      +++
Sbjct: 430  LDREERDAYNLRVTATDSGSPP---LRAEAAFVLHVTDVNDNAPAFDRQLYRPEPLPEVA 486

Query: 165  VTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR 224
            +  + V+ ++ A D D G N  + Y++  G     FSID  SG ++   +LDYE     +
Sbjct: 487  LPGSFVV-RVTARDPDQGTNGQVTYSLAPGAHTHWFSIDPTSGIITTAASLDYELEPQPQ 545

Query: 225  LVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA 284
            L++ A DGG P  +++  + + ++DVNDN P+F  + +  S+ E    G   ++V A DA
Sbjct: 546  LIVVATDGGLPPLASSATVSVALQDVNDNEPQFQRTFYNASLPEGTQPGTCFLQVTATDA 605

Query: 285  DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET-QAKYQLLVTATDGGD 343
            D G    L+Y++       +   P  ID  SG V T+  LDR+   + +   VTA DGG 
Sbjct: 606  DSGPFGLLSYSL-GAGLGSSGSPPFRIDAHSGDVCTTRTLDRDQGPSSFDFTVTAVDGGG 664

Query: 344  PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHY 401
                +                 F P +Y   ++   PPGT V+ L A D D+ +  RL Y
Sbjct: 665  --LKSMVYVKVFLSDENDNPPQFYPREYAASISAQSPPGTAVLRLRAHDPDQGSHGRLSY 722

Query: 402  EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINI 459
             I  GN+   F++  Q+  GL+TVA PL  +      L + A D GG     +A V I+I
Sbjct: 723  HILAGNSPPLFTLDEQS--GLLTVAWPLARRANSVVQLEIGAEDGGGLQAEPSARVDISI 780

Query: 460  TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAH 519
                   P+FE   Y  SV ED   GT+V +V A  +  G  A +T SLS          
Sbjct: 781  VPGTPTPPIFEQLQYVFSVPEDVAPGTSVGIVQA-HNPPGRLAPVTLSLSG-------GD 832

Query: 520  HDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNE 578
                F ++  +G + T + LDRE + G +L +  R G GVP       V + + DVNDN 
Sbjct: 833  PRGLFSLDAVSGLLQTLRPLDRELL-GPVLELEVRAGSGVPPAFAVARVRVLLDDVNDNS 891

Query: 579  PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638
            P F     T  +  +   GT +  + A D D G+N R+ + L       G+F +DP +G 
Sbjct: 892  PAFPAPEDTVLLPPNTAPGTPIYTLRALDPDSGVNSRVTFTL--LAGGGGAFTVDPTTGH 949

Query: 639  IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS--PPVFESDCLTFYI 696
            +R  + L       H+L+  A DGG+PP++S   + + ++D+      P F S      +
Sbjct: 950  VRLMRPLGPSGGPAHELELEARDGGSPPRTSHFRLRVVVQDVGTRGLAPRFNSPTYRVDL 1009

Query: 697  SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756
               +  GT + +++A  PD GP   + Y +     S+ F LE + G     L     LD 
Sbjct: 1010 PSGTTAGTQVLQVQAQAPDGGP---ITYHLAAEGASSPFGLEPQSG----WLWVRAALDR 1062

Query: 757  ESPRKKYELVIRAAS------PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV 810
            E+ ++ Y L + A S              V + + + N+++P + +        ++  P 
Sbjct: 1063 EA-QELYILKVMAVSGSKAELGQQTGTATVRVSILNQNEHSPRLSEDPTFLAVAENQPPG 1121

Query: 811  GPFGRVPAYDAD--VTDKLQYRILS-GNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867
               GRV A D D     +L Y +     ++    ++  TG +T    L+        + V
Sbjct: 1122 TSVGRVFATDRDSGPNGRLTYSLQQLSEDSKAFRIHPQTGEVTTLQTLDREQQSSYQLLV 1181

Query: 868  SVTDG 872
             V DG
Sbjct: 1182 QVQDG 1186



 Score =  268 bits (656), Expect = 2e-69
 Identities = 244/854 (28%), Positives = 382/854 (44%), Gaps = 66/854 (7%)

Query: 18   DHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXX 77
            +  P F     EA++RE A  GT +++ +A     G N  + Y+I       L+  +   
Sbjct: 2063 ERGPRFPRASSEATIRENAPPGTPIVSPRAVHAG-GTNGPITYSI-------LSGNE--- 2111

Query: 78   XXXXXXXXVQDVFRIDGRSGALLTRAS--LDREKVARYTVLVKATDQASPVSDRLSSTAT 135
                     +  F I   +GA+  R++  LD E   R  ++++A       S    +   
Sbjct: 2112 ---------KGTFSIQPSTGAITVRSAEGLDFEVSPRLRLVLQAE------SGGAFAFTV 2156

Query: 136  IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195
            + + + D NDN P+F    Y   + E   + + P++ +++A D D G+   I Y++    
Sbjct: 2157 LTLTLQDANDNAPRFLRPHYVAFLPESRPL-EGPLL-QVEADDLDQGSGGQISYSLAASQ 2214

Query: 196  -TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNA 254
              +  F +D  +G ++    LD E     RLV+ A D GSP+   +  L + + D NDN 
Sbjct: 2215 PARGLFHVDPTTGTITTTAILDREIWAETRLVLMATDRGSPALVGSATLTVMVIDTNDNR 2274

Query: 255  PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR 314
            P      ++  VSE+  +G  I +V   D D G    L Y ++    +G  D P ++   
Sbjct: 2275 PTI-PQPWELRVSEDALLGSEIAQVTGNDVDSG--PVLWYVLSP---SGPQD-PFSVGRY 2327

Query: 315  SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374
             G V  +G LD E   +YQL + A DG   P    A               F    Y+V 
Sbjct: 2328 GGRVSLTGPLDFEQCDRYQLQLLAHDG---PHEGRANLTVLVEDVNDNAPAFSQSLYQVM 2384

Query: 375  LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434
            L E  PPG+ +++++ATD D     H      +    FS+   NG  L T+   +    +
Sbjct: 2385 LLEHTPPGSAILSVSATDRDSGANGHISYHLASPADGFSVDPNNGT-LFTIVGTVALGHD 2443

Query: 435  RRYVLTV--SATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
                + V   A D G  GR+  A V + + D N++AP F  + Y  +V ED P G+T+L 
Sbjct: 2444 GSGAVDVVLEARDHGAPGRAARATVHVQLQDQNDHAPSFTLSHYRVAVTEDLPPGSTLLT 2503

Query: 491  VSATDSDVG-INAQITYSLSSEISNEA------VAHHDQQFVINPQT-GAITTNKLLDRE 542
            + ATD+D    +A + YS+ S            +A   +     P+  G +   + LD E
Sbjct: 2504 LEATDADGSRSHAAVDYSIISGNWGRVFQLEPRLAEAGESAGPGPRALGCLVLLEPLDFE 2563

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
            +++ Y LTV A D G P  S    V ++V+DVNDN PVF +  Y   + ED  VG  +  
Sbjct: 2564 SLTQYNLTVAAADRGQPPQSSVVPVTVTVLDVNDNPPVFTRASYRVTVPEDTPVGAELLH 2623

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
            V A+DAD G +G + + +   D   G F +D +SG +R   ALD E+ A H L   A D 
Sbjct: 2624 VEASDADPGPHGLVRFTVSSGD-PSGLFELDESSGTLRLAHALDCETQARHQLVVQAADP 2682

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
                  +   V I+++D+ND  P F  + L+  ++EN P GT +  + A D D G    +
Sbjct: 2683 AGA-HFALAPVTIEVQDVNDHGPAFPLNLLSTSVAENQPPGTLVTTLHAIDGDAGAFGRL 2741

Query: 723  HYSI----KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDV 778
             YS+     G +   +F+L +  G    EL   V  DYE       LV  A +  L   V
Sbjct: 2742 RYSLLEAGPGPEGREAFALNSSTG----ELRARVPFDYEHTESFRLLVGAADAGNLSASV 2797

Query: 779  RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD-VTDKLQYRILSGNNA 837
             V +LVT  ++  PV       F   +        G V A D D   D L    L+  ++
Sbjct: 2798 TVSVLVTGEDEYDPVFLAPAFHFQVPEGARRGHSLGHVQATDEDGGADGLVLYSLA-TSS 2856

Query: 838  NLILLNETTGSMTL 851
                +N+TTG++ L
Sbjct: 2857 PYFGINQTTGALYL 2870



 Score =  265 bits (650), Expect = 1e-68
 Identities = 226/778 (29%), Positives = 342/778 (43%), Gaps = 66/778 (8%)

Query: 15   DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
            D ND+ P F+   Y AS+ EG   GT  L + ATD D G    + Y++      + +P  
Sbjct: 570  DVNDNEPQFQRTFYNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLGAGLGSSGSPP- 628

Query: 75   AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREK-VARYTVLVKATDQASPVSDRLSST 133
                           FRID  SG + T  +LDR++  + +   V A D        L S 
Sbjct: 629  ---------------FRIDAHSGDVCTTRTLDRDQGPSSFDFTVTAVDGGG-----LKSM 668

Query: 134  ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG 193
              + V + D+NDN PQF  + Y  S+           + +++A D D G++  + Y I+ 
Sbjct: 669  VYVKVFLSDENDNPPQFYPREYAASISAQSP--PGTAVLRLRAHDPDQGSHGRLSYHILA 726

Query: 194  GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDN 253
            GN+   F++D  SG +++   L        +L I A+DGG      + ++ I+I      
Sbjct: 727  GNSPPLFTLDEQSGLLTVAWPLARRANSVVQLEIGAEDGGGLQAEPSARVDISIVPGTPT 786

Query: 254  APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313
             P F    +  SV E+V  G S+  VQA++   G  A +T +++  D  G   L    D 
Sbjct: 787  PPIFEQLQYVFSVPEDVAPGTSVGIVQAHNPP-GRLAPVTLSLSGGDPRGLFSL----DA 841

Query: 314  RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373
             SG + T   LDRE       L      G PP  A A               F   +  V
Sbjct: 842  VSGLLQTLRPLDRELLGPVLELEVRAGSGVPPAFAVARVRVLLDDVNDNSPAFPAPEDTV 901

Query: 374  ELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431
             L  +  PGTP+ TL A D D   ++R+ + +  G   G F++    G   + + +PL  
Sbjct: 902  LLPPNTAPGTPIYTLRALDPDSGVNSRVTFTLLAGGG-GAFTVDPTTGH--VRLMRPLGP 958

Query: 432  KQERRYVLTVSATDSGGRSDTAMVQINIT----DANNYAPVFENAPYTASVFEDAPIGTT 487
                 + L + A D G    T+  ++ +          AP F +  Y   +      GT 
Sbjct: 959  SGGPAHELELEARDGGSPPRTSHFRLRVVVQDVGTRGLAPRFNSPTYRVDLPSGTTAGTQ 1018

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
            VL V A   D G    ITY L++E ++         F + PQ+G +     LDRE    Y
Sbjct: 1019 VLQVQAQAPDGG---PITYHLAAEGASSP-------FGLEPQSGWLWVRAALDREAQELY 1068

Query: 548  LLTVTARDGGVPSLSD---TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
            +L V A  G    L     T  V +S+++ N++ P   +      + E+   GTSV +V 
Sbjct: 1069 ILKVMAVSGSKAELGQQTGTATVRVSILNQNEHSPRLSEDPTFLAVAENQPPGTSVGRVF 1128

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            ATD D G NGR+ Y L     +  +F I P +G + T + LDRE  +++ L     DGG+
Sbjct: 1129 ATDRDSGPNGRLTYSLQQLSEDSKAFRIHPQTGEVTTLQTLDREQQSSYQLLVQVQDGGS 1188

Query: 665  PPQSSTVIVHIKIEDINDSPPVF------ESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
            PP+S+T  VH+ + D+ND+ P F          L   + +  P GT +  ++A DPDEG 
Sbjct: 1189 PPRSTTGTVHVAVLDLNDNSPTFLQASGAAGGGLPIQVPDRVPPGTLVTTLQAKDPDEGE 1248

Query: 719  NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPP 773
            N  + Y++  G  S  FSL    G    EL+T   L   + R  Y L + A    SPP
Sbjct: 1249 NGTILYTLT-GPGSELFSLHPHSG----ELLTAAPL-IRAERPHYVLTLSAHDQGSPP 1300



 Score =  248 bits (607), Expect = 2e-63
 Identities = 244/896 (27%), Positives = 399/896 (44%), Gaps = 78/896 (8%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            ++ ++ + D ND+ P F  ++Y AS+   +  GT VL L+A D D G +  + Y I    
Sbjct: 669  VYVKVFLSDENDNPPQFYPREYAASISAQSPPGTAVLRLRAHDPDQGSHGRLSYHI---L 725

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
            A    P                +F +D +SG L     L R   +   + + A D     
Sbjct: 726  AGNSPP----------------LFTLDEQSGLLTVAWPLARRANSVVQLEIGAEDGGGLQ 769

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
            ++    +A + ++I+      P F +  Y  SV ED  V     +  ++A +   G  + 
Sbjct: 770  AE---PSARVDISIVPGTPTPPIFEQLQYVFSVPED--VAPGTSVGIVQAHNPP-GRLAP 823

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGGSPSRSNTTQLLI 245
            +  ++ GG+ +  FS+D++SG +  ++ LD E +     L +RA  G  P+ +   ++ +
Sbjct: 824  VTLSLSGGDPRGLFSLDAVSGLLQTLRPLDRELLGPVLELEVRAGSGVPPAFA-VARVRV 882

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
             + DVNDN+P F        +  N   G  I  ++A D D GVN+ +T+T+      G  
Sbjct: 883  LLDDVNDNSPAFPAPEDTVLLPPNTAPGTPIYTLRALDPDSGVNSRVTFTL----LAGGG 938

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA--TATXXXXXXXXXXXX 363
                T+DP +G V     L       ++L + A DGG PPR++                 
Sbjct: 939  G-AFTVDPTTGHVRLMRPLGPSGGPAHELELEARDGGSPPRTSHFRLRVVVQDVGTRGLA 997

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423
              F    Y V+L      GT V+ + A  A +   + Y +        F +  Q+  G +
Sbjct: 998  PRFNSPTYRVDLPSGTTAGTQVLQVQA-QAPDGGPITYHLAAEGASSPFGLEPQS--GWL 1054

Query: 424  TVAQPLDFKQERRYVLTV-----SATDSGGRSDTAMVQINITDANNYAPVFENAPYTASV 478
             V   LD + +  Y+L V     S  + G ++ TA V+++I + N ++P     P   +V
Sbjct: 1055 WVRAALDREAQELYILKVMAVSGSKAELGQQTGTATVRVSILNQNEHSPRLSEDPTFLAV 1114

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             E+ P GT+V  V ATD D G N ++TYSL  ++S ++ A     F I+PQTG +TT + 
Sbjct: 1115 AENQPPGTSVGRVFATDRDSGPNGRLTYSL-QQLSEDSKA-----FRIHPQTGEVTTLQT 1168

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA------NIME 592
            LDRE  S Y L V  +DGG P  S T  V ++V+D+NDN P F Q    A       + +
Sbjct: 1169 LDREQQSSYQLLVQVQDGGSPPRSTTGTVHVAVLDLNDNSPTFLQASGAAGGGLPIQVPD 1228

Query: 593  DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652
                GT V+ + A D D G NG I Y L     E   F + P SG + T   L R     
Sbjct: 1229 RVPPGTLVTTLQAKDPDEGENGTILYTLTGPGSE--LFSLHPHSGELLTAAPLIRAERPH 1286

Query: 653  HDLKAVAIDGGTPPQSSTVIVHIKI---EDINDSPP-VFESD-------CLTFYISENSP 701
            + L   A D G+PP+S+++ + +++     + + PP + E D        LT   +E   
Sbjct: 1287 YVLTLSAHDQGSPPRSASLQLLVQVLPSARLAEPPPDLAERDPAAPVPVVLTVTAAEGLR 1346

Query: 702  IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761
             G+ +G + A +P  G  A+ +  + G D   +F+L+   G     L     LD+E+   
Sbjct: 1347 PGSLLGSVAAPEP-AGVGALTYTLVGGADPEGTFALDAASG----RLYLARPLDFEAGPP 1401

Query: 762  KYELVIRAASPPLWND--VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY 819
               L +RA  P       +RV++ V D N++AP      +     ++  P        A 
Sbjct: 1402 WRALTVRAEGPGGAGARLLRVQVQVQDENEHAPAFARDPLALALPENPEPGAALYTFRAS 1461

Query: 820  DAD---VTDKLQYRILSGN-NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            DAD       ++YR+L        + L+  TG+++    L+        + V  TD
Sbjct: 1462 DADGPGPNSDVRYRLLRQEPPVPALRLDARTGALSAPRGLDRETTPALLLLVEATD 1517



 Score =  198 bits (483), Expect = 2e-48
 Identities = 154/518 (29%), Positives = 240/518 (46%), Gaps = 23/518 (4%)

Query: 369 GQYEVELAEDEPPGTPVVTLTA-TDADEDNRLHYEITGGNTRG-RFSITSQNGRGLITVA 426
           G  ++++ E++P GT +  ++A   A     L Y I+     G    +      G++  A
Sbjct: 45  GSLDLQIDEEQPAGTLIGDISAGLPAGTAAPLMYFISAQEGSGVGTDLAIDEHSGVVRTA 104

Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
           + LD +Q  RY  T    D      T  V + + D N++AP F  A     V E    GT
Sbjct: 105 RVLDREQRDRYRFTAVTPDGA----TVEVTVRVADINDHAPAFPQARAALQVPEHTAFGT 160

Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
              +  A D+D G      Y+LS + + E      +          +     LDRE  S 
Sbjct: 161 RYPLEPARDADAGRLGTQGYALSGDGAGETFRLETRPGPDGTPVPELVVTGELDRENRSH 220

Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
           Y+L + A DGG P       ++++++D+ND+ P F Q  Y A + E    G+ V QV A+
Sbjct: 221 YMLQLEAYDGGSPPRRAQALLDVTLLDINDHAPAFNQSRYHAVVSESLAPGSPVLQVFAS 280

Query: 607 DADVGLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
           DAD G+NG + YE++ +  E +G F ID  +G+++  + LD E    H+L   A DGG  
Sbjct: 281 DADAGVNGAVTYEINRRQSEGDGPFSIDAHTGLLQLERPLDFEQRRVHELVVQARDGGAH 340

Query: 666 PQSSTVIVHIKIEDINDSPP----VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
           P+  +  V + + D ND+ P    +F S   +  +SE +P G  +  I   DPD+G  A 
Sbjct: 341 PELGSAFVTVHVRDANDNQPSMTVIFLSADGSPQVSEAAPPGQLVARISVSDPDDGDFAH 400

Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDV 778
           V+ S++GG+    F+L T Q S    +     LD E  R  Y L + A    SPPL  + 
Sbjct: 401 VNVSLEGGE--GHFALST-QDSVIYLVCVARRLDREE-RDAYNLRVTATDSGSPPLRAEA 456

Query: 779 RVEILVTDVNDNAPVMKDFQIIFNN--YKDCFPVGPFGRVPAYDAD--VTDKLQYRILSG 834
              + VTDVNDNAP   D Q+       +   P     RV A D D     ++ Y +  G
Sbjct: 457 AFVLHVTDVNDNAPAF-DRQLYRPEPLPEVALPGSFVVRVTARDPDQGTNGQVTYSLAPG 515

Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            + +   ++ T+G +T +  L+  +     + V  TDG
Sbjct: 516 AHTHWFSIDPTSGIITTAASLDYELEPQPQLIVVATDG 553



 Score =  184 bits (447), Expect = 4e-44
 Identities = 162/579 (27%), Positives = 250/579 (43%), Gaps = 45/579 (7%)

Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325
           + E  P G  I  + A     G  A L Y ++ ++ +G V   + ID  SG V T+  LD
Sbjct: 51  IDEEQPAGTLIGDISA-GLPAGTAAPLMYFISAQEGSG-VGTDLAIDEHSGVVRTARVLD 108

Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
           RE + +Y+      DG      AT                F   +  +++ E    GT  
Sbjct: 109 REQRDRYRFTAVTPDG------ATVEVTVRVADINDHAPAFPQARAALQVPEHTAFGTRY 162

Query: 386 VTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRG-----LITVAQPLDFKQERRYV 438
               A DAD        Y ++G      F + ++ G        + V   LD +    Y+
Sbjct: 163 PLEPARDADAGRLGTQGYALSGDGAGETFRLETRPGPDGTPVPELVVTGELDRENRSHYM 222

Query: 439 LTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496
           L + A D G   R   A++ + + D N++AP F  + Y A V E    G+ VL V A+D+
Sbjct: 223 LQLEAYDGGSPPRRAQALLDVTLLDINDHAPAFNQSRYHAVVSESLAPGSPVLQVFASDA 282

Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556
           D G+N  +TY +     N   +  D  F I+  TG +   + LD E    + L V ARDG
Sbjct: 283 DAGVNGAVTYEI-----NRRQSEGDGPFSIDAHTGLLQLERPLDFEQRRVHELVVQARDG 337

Query: 557 GVPSLSDTTDVEISVVDVNDNEP----VFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612
           G      +  V + V D NDN+P    +F     +  + E A  G  V+++  +D D G 
Sbjct: 338 GAHPELGSAFVTVHVRDANDNQPSMTVIFLSADGSPQVSEAAPPGQLVARISVSDPDDGD 397

Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIR---TNKALDRESVATHDLKAVAIDGGTPPQSS 669
              ++  L   +  EG F +     VI      + LDRE    ++L+  A D G+PP  +
Sbjct: 398 FAHVNVSL---EGGEGHFALSTQDSVIYLVCVARRLDREERDAYNLRVTATDSGSPPLRA 454

Query: 670 TVIVHIKIEDINDSPPVFESDCL-TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
                + + D+ND+ P F+        + E +  G+ +  + A DPD+G N  V YS+  
Sbjct: 455 EAAFVLHVTDVNDNAPAFDRQLYRPEPLPEVALPGSFVVRVTARDPDQGTNGQVTYSLAP 514

Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR--AASPPLWNDVRVEILVTD 786
           G  ++ FS++   G     + T   LDYE   +   +V+      PPL +   V + + D
Sbjct: 515 GAHTHWFSIDPTSGI----ITTAASLDYELEPQPQLIVVATDGGLPPLASSATVSVALQD 570

Query: 787 VNDNAPVMKDFQIIFNNY---KDCFPVGPFGRVPAYDAD 822
           VNDN P    FQ  F N    +   P   F +V A DAD
Sbjct: 571 VNDNEP---QFQRTFYNASLPEGTQPGTCFLQVTATDAD 606



 Score =  146 bits (354), Expect = 8e-33
 Identities = 108/389 (27%), Positives = 175/389 (44%), Gaps = 16/389 (4%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGK-NAEVEYTIELV 65
            +H Q+   D NDH+P F +  Y  +V E    G+T+LTL+ATD D  + +A V+Y+I  +
Sbjct: 2468 VHVQLQ--DQNDHAPSFTLSHYRVAVTEDLPPGSTLLTLEATDADGSRSHAAVDYSI--I 2523

Query: 66   TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125
            +    N               +         G L+    LD E + +Y + V A D+  P
Sbjct: 2524 SG---NWGRVFQLEPRLAEAGESAGPGPRALGCLVLLEPLDFESLTQYNLTVAAADRGQP 2580

Query: 126  VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
                 SS   + V ++D NDN P F+  +Y V+V ED  V     +  ++A+DAD G + 
Sbjct: 2581 PQ---SSVVPVTVTVLDVNDNPPVFTRASYRVTVPEDTPV--GAELLHVEASDADPGPHG 2635

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
             +R+ +  G+    F +D  SG + L   LD E    ++LV++A D    +      + I
Sbjct: 2636 LVRFTVSSGDPSGLFELDESSGTLRLAHALDCETQARHQLVVQAADPAG-AHFALAPVTI 2694

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
             ++DVND+ P F  +L   SV+EN P G  +  + A D D G    L Y++ +       
Sbjct: 2695 EVQDVNDHGPAFPLNLLSTSVAENQPPGTLVTTLHAIDGDAGAFGRLRYSLLEAGPGPEG 2754

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
                 ++  +G +      D E    ++LLV A D G+   SA+ T              
Sbjct: 2755 REAFALNSSTGELRARVPFDYEHTESFRLLVGAADAGN--LSASVTVSVLVTGEDEYDPV 2812

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDAD 394
            F+   +  ++ E    G  +  + ATD D
Sbjct: 2813 FLAPAFHFQVPEGARRGHSLGHVQATDED 2841



 Score =  110 bits (265), Expect = 5e-22
 Identities = 99/353 (28%), Positives = 157/353 (44%), Gaps = 39/353 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + VLD ND+ PVF    Y  +V E    G  +L ++A+D D G +  V +T+   + D  
Sbjct: 2590 VTVLDVNDNPPVFTRASYRVTVPEDTPVGAELLHVEASDADPGPHGLVRFTVS--SGDP- 2646

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                              +F +D  SG L    +LD E  AR+ ++V+A D A       
Sbjct: 2647 ----------------SGLFELDESSGTLRLAHALDCETQARHQLVVQAADPAGAHF--- 2687

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             + A + + + D ND+ P F     + SV E+       ++  + A D D GA   +RY+
Sbjct: 2688 -ALAPVTIEVQDVNDHGPAFPLNLLSTSVAEN--QPPGTLVTTLHAIDGDAGAFGRLRYS 2744

Query: 191  II----GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            ++    G   +  F+++S +G++      DYE   S+RL++ A D G+ S S T  +L+ 
Sbjct: 2745 LLEAGPGPEGREAFALNSSTGELRARVPFDYEHTESFRLLVGAADAGNLSASVTVSVLVT 2804

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM-TDKDYTG-- 303
              D  D  P F    F   V E    G+S+  VQA D D G +  + Y++ T   Y G  
Sbjct: 2805 GEDEYD--PVFLAPAFHFQVPEGARRGHSLGHVQATDEDGGADGLVLYSLATSSPYFGIN 2862

Query: 304  --NVDLPITID---PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
                 L + +D   P SG   + G      +A  +L +     G  P S +AT
Sbjct: 2863 QTTGALYLRVDSRAPGSGTATSGGGGRTRREAPRELRLEVIARGPLPGSRSAT 2915


>UniRef50_Q4SVG4 Cluster: Chromosome 1 SCAF13759, whole genome shotgun
            sequence; n=7; Tetraodontidae|Rep: Chromosome 1
            SCAF13759, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 3762

 Score =  313 bits (769), Expect = 4e-83
 Identities = 266/904 (29%), Positives = 433/904 (47%), Gaps = 96/904 (10%)

Query: 3    VPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
            V FC   +I + D ND+ P F   +Y+ S++   + G+ V+ + A D D G+NA+V YT+
Sbjct: 2510 VAFCT-VRIILTDENDNVPQFAASEYQVSIQSTVNKGSPVVHIMAYDADEGRNADVTYTV 2568

Query: 63   ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122
            +         E+A           +DV  I+  +G +  + SL   +   +   V+A D 
Sbjct: 2569 D-------EAEEA----------TEDVIEINPFTGLVTVKDSLVGMENRIFNFKVQARDG 2611

Query: 123  ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
            + P     ++T  + V ++      PQFSE  YT S     +V D PV  +I +  A   
Sbjct: 2612 SLPF---YNATVPVQVRVLPPEVPLPQFSEPLYTFS-----AVEDAPVGTEIGSVRA--A 2661

Query: 183  ANSAIRYAIIGGNT-----QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ-DGGSPS 236
            +N+ + Y+++ GNT        FS+D  SG + L K +D+E+ + Y++ + AQ +    +
Sbjct: 2662 SNTPLIYSLVDGNTLENNKDKVFSLDEDSGTLVLQKPMDHERTKWYQIDVMAQGNHNGTA 2721

Query: 237  RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
             ++   + I ++DVNDN P F  S ++  ++EN+P G ++++V A DAD   N  +TY++
Sbjct: 2722 VASLVSISIQVQDVNDNEPLFDASPYRAFLAENMPAGTTVIQVTANDADSETNGLVTYSL 2781

Query: 297  -----TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR-SATA 350
                  +++  G  ++  +ID  SGW+ T+ + D E    Y+  V ATD G   R S++ 
Sbjct: 2782 EALPEEEEEEAGATEM-FSIDEESGWITTTQEADCEAVRVYRFSVVATDNGGGLRLSSSV 2840

Query: 351  TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRL-HYEITGGN 407
                           F    Y   + E+  PG  +V++T  DAD   +NRL    IT G+
Sbjct: 2841 LVEVTVTDENDNPPKFSLEAYRGSVVENSSPGEVLVSMTTADADVSLENRLVTCYITDGD 2900

Query: 408  TRGRFSI--TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNY 465
              G F+I   S+ G GLI + QPLD + + R+ L V ATD G    +  V +++ D N+ 
Sbjct: 2901 PLGHFAIIQQSEGGWGLI-LTQPLDREVKDRHALRVMATD-GKFQASVSVDVHVLDINDN 2958

Query: 466  APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525
            +P  E   YT +V E++P    VL VSA D DVG N Q++YSL           +  +F 
Sbjct: 2959 SPQCEQLVYTEAVMENSPSSRFVLKVSAVDPDVGANGQVSYSLHGP--------NADKFH 3010

Query: 526  INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585
            +N +TG + T  +LDRE    Y L   A DGG    S  +D+ + + D+NDN P F    
Sbjct: 3011 LNYRTGELLTLAVLDREAEPEYNLVAKATDGG--GRSCQSDILLMIQDMNDNPPRFSSSH 3068

Query: 586  YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645
            Y   + ++  V T ++ + A D D                    F +D  SG++R  + L
Sbjct: 3069 YQLTVFDNTTVHTPIAVLYAKDPDTC----------------SFFSLDEFSGLLRLERPL 3112

Query: 646  DRESVATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
              ++  T +LK  A D G P    S   V + +  ++D  PVF S   T  + E+  +G+
Sbjct: 3113 TPDAPPTFELKVKATDRGLPRHLYSIATVTVAVVSLDDYQPVFLSSEYTAQLPESFAVGS 3172

Query: 705  TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKY 763
             +  + A   D G    V Y I  G++   F L++R G     L+T+V  LD+E+ R  Y
Sbjct: 3173 QVLSLSALTRDGGGPDPVAYRIVSGNEDGRFLLDSRTG-----LLTLVAPLDFEASRTYY 3227

Query: 764  ELVI-RAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD 822
              V  R     L +   V + VTDVNDNAPV ++        +D  P     +VPA +  
Sbjct: 3228 LSVEGRRGKQTLSDITTVMVNVTDVNDNAPVFEEGGYRVEIKEDLPPGSLVMKVPAQEPP 3287

Query: 823  V-------TDK-------LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVS 868
            V       +D+       L+Y I+SG+      ++  +G ++++  L+       ++ V 
Sbjct: 3288 VFGGKVTASDQDGPSNSLLRYSIVSGDPLQQFSIHPRSGEISVAAALDREEVPHYSLTVQ 3347

Query: 869  VTDG 872
              DG
Sbjct: 3348 AADG 3351



 Score =  310 bits (762), Expect = 3e-82
 Identities = 259/883 (29%), Positives = 400/883 (45%), Gaps = 64/883 (7%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I V D ND++PVF  + Y A V EG   GT+V+ + A+D D G+N ++  T  ++  + 
Sbjct: 2203 EIEVEDVNDNAPVFSQRAYGAVVAEGLPVGTSVVQVSASDGDSGRNRDL--TFHMLRTER 2260

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
               E                F ID  +G ++T+  LD E   ++ + ++ATD  +     
Sbjct: 2261 NETE---------------FFDIDPHTGVIVTKQVLDHEGTNQFHLKIRATDNGTA---P 2302

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            LSS A++ VN+ D NDN P F    Y  ++DE        ++ KI+A+D D G  + ++Y
Sbjct: 2303 LSSEASVLVNVTDVNDNPPDFVSSQYEATLDEKAKC--GHIVIKIQASDPDSGDLNKLQY 2360

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             I+ GN    F+I+  SG VS            Y L +   DG       T ++ I++  
Sbjct: 2361 KILSGNEGRYFNINQSSGIVSFSNVCRRNLEPFYNLTVAVSDG---VFQKTARVNIDMLS 2417

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
             N ++P F  S+++  ++EN  +G  ++R+ A D DEG+   + YT+ +K      D  +
Sbjct: 2418 TNKHSPSFKQSVYEAELAENAEVGTQVIRLAAIDPDEGLYGSVDYTIINK----LADEKL 2473

Query: 310  TIDPRSGWVYTSGQLDRETQAK--YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
             ID   G + T+  LDRE  A+    + V A DGG   + A  T              F 
Sbjct: 2474 AID-SDGQMVTTQPLDRENPAQRIIAVKVMAKDGGG--KVAFCTVRIILTDENDNVPQFA 2530

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITV 425
              +Y+V +      G+PVV + A DADE     + Y +          I      GL+TV
Sbjct: 2531 ASEYQVSIQSTVNKGSPVVHIMAYDADEGRNADVTYTVDEAEEATEDVIEINPFTGLVTV 2590

Query: 426  AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
               L   + R +   V A D      + T  VQ+ +       P F    YT S  EDAP
Sbjct: 2591 KDSLVGMENRIFNFKVQARDGSLPFYNATVPVQVRVLPPEVPLPQFSEPLYTFSAVEDAP 2650

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
            +GT +  V A       N  + YSL     N    + D+ F ++  +G +   K +D E 
Sbjct: 2651 VGTEIGSVRAAS-----NTPLIYSLVD--GNTLENNKDKVFSLDEDSGTLVLQKPMDHER 2703

Query: 544  MSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
               Y + V A+ +    +++    + I V DVNDNEP+F    Y A + E+   GT+V Q
Sbjct: 2704 TKWYQIDVMAQGNHNGTAVASLVSISIQVQDVNDNEPLFDASPYRAFLAENMPAGTTVIQ 2763

Query: 603  VGATDADVGLNGRIHYELD--PKDREEGS-----FVIDPASGVIRTNKALDRESVATHDL 655
            V A DAD   NG + Y L+  P++ EE +     F ID  SG I T +  D E+V  +  
Sbjct: 2764 VTANDADSETNGLVTYSLEALPEEEEEEAGATEMFSIDEESGWITTTQEADCEAVRVYRF 2823

Query: 656  KAVAID-GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
              VA D GG    SS+V+V + + D ND+PP F  +     + ENS  G  +  +   D 
Sbjct: 2824 SVVATDNGGGLRLSSSVLVEVTVTDENDNPPKFSLEAYRGSVVENSSPGEVLVSMTTADA 2883

Query: 715  DEG-PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP 773
            D    N +V   I  GD    F++  +Q      L+    LD E  + ++ L + A    
Sbjct: 2884 DVSLENRLVTCYITDGDPLGHFAI-IQQSEGGWGLILTQPLDRE-VKDRHALRVMATDGK 2941

Query: 774  LWNDVRVEILVTDVNDNAPVMKDFQIIFNN-YKDCFPVGPFG-RVPAYDADV--TDKLQY 829
                V V++ V D+NDN+P  +  Q+++     +  P   F  +V A D DV    ++ Y
Sbjct: 2942 FQASVSVDVHVLDINDNSPQCE--QLVYTEAVMENSPSSRFVLKVSAVDPDVGANGQVSY 2999

Query: 830  RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
              L G NA+   LN  TG +     L+        +    TDG
Sbjct: 3000 S-LHGPNADKFHLNYRTGELLTLAVLDREAEPEYNLVAKATDG 3041



 Score =  285 bits (698), Expect = 2e-74
 Identities = 237/799 (29%), Positives = 371/799 (46%), Gaps = 64/799 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +NV D ND+ P F   QYEA++ E A  G  V+ ++A+D D G   +++Y I       L
Sbjct: 2311 VNVTDVNDNPPDFVSSQYEATLDEKAKCGHIVIKIQASDPDSGDLNKLQYKI-------L 2363

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +  +               F I+  SG +       R     Y + V  +D         
Sbjct: 2364 SGNEGRY------------FNINQSSGIVSFSNVCRRNLEPFYNLTVAVSDGV------F 2405

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
              TA ++++++  N + P F +  Y   + E+  V     + ++ A D D G   ++ Y 
Sbjct: 2406 QKTARVNIDMLSTNKHSPSFKQSVYEAELAENAEVGTQ--VIRLAAIDPDEGLYGSVDYT 2463

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            II      + +IDS  G +   + LD E    R   + + A+DGG      T ++++   
Sbjct: 2464 IINKLADEKLAIDS-DGQMVTTQPLDRENPAQRIIAVKVMAKDGGGKVAFCTVRIILT-- 2520

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            D NDN P+F  S +Q S+   V  G  +V + AYDADEG NA++TYT+ D+      D+ 
Sbjct: 2521 DENDNVPQFAASEYQVSIQSTVNKGSPVVHIMAYDADEGRNADVTYTV-DEAEEATEDV- 2578

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
            I I+P +G V     L       +   V A DG  P  +AT                F  
Sbjct: 2579 IEINPFTGLVTVKDSLVGMENRIFNFKVQARDGSLPFYNATVPVQVRVLPPEVPLPQFSE 2638

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT--RGRFSITS-QNGRGLITV 425
              Y     ED P GT + ++ A     +  L Y +  GNT    +  + S     G + +
Sbjct: 2639 PLYTFSAVEDAPVGTEIGSVRAA---SNTPLIYSLVDGNTLENNKDKVFSLDEDSGTLVL 2695

Query: 426  AQPLDFKQERRYVLTVSATDSGGRSDTAM-----VQINITDANNYAPVFENAPYTASVFE 480
             +P+D ++ + Y + V A   G  + TA+     + I + D N+  P+F+ +PY A + E
Sbjct: 2696 QKPMDHERTKWYQIDVMA--QGNHNGTAVASLVSISIQVQDVNDNEPLFDASPYRAFLAE 2753

Query: 481  DAPIGTTVLVVSATDSDVGINAQITYSLSS-EISNEAVAHHDQQFVINPQTGAITTNKLL 539
            + P GTTV+ V+A D+D   N  +TYSL +     E  A   + F I+ ++G ITT +  
Sbjct: 2754 NMPAGTTVIQVTANDADSETNGLVTYSLEALPEEEEEEAGATEMFSIDEESGWITTTQEA 2813

Query: 540  DRETMSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            D E +  Y  +V A D GG   LS +  VE++V D NDN P F  + Y  +++E++  G 
Sbjct: 2814 DCEAVRVYRFSVVATDNGGGLRLSSSVLVEVTVTDENDNPPKFSLEAYRGSVVENSSPGE 2873

Query: 599  SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS----GVIRTNKALDRESVATHD 654
             +  +   DADV L  R+           G F I   S    G+I T + LDRE    H 
Sbjct: 2874 VLVSMTTADADVSLENRLVTCYITDGDPLGHFAIIQQSEGGWGLILT-QPLDREVKDRHA 2932

Query: 655  LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
            L+ +A DG      ++V V + + DIND+ P  E    T  + ENSP    + ++ A DP
Sbjct: 2933 LRVMATDG---KFQASVSVDVHVLDINDNSPQCEQLVYTEAVMENSPSSRFVLKVSAVDP 2989

Query: 715  DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL 774
            D G N  V YS+  G +++ F L  R G    EL+T+  LD E+   +Y LV +A     
Sbjct: 2990 DVGANGQVSYSLH-GPNADKFHLNYRTG----ELLTLAVLDREA-EPEYNLVAKATDGGG 3043

Query: 775  WN-DVRVEILVTDVNDNAP 792
             +    + +++ D+NDN P
Sbjct: 3044 RSCQSDILLMIQDMNDNPP 3062



 Score =  283 bits (694), Expect = 5e-74
 Identities = 196/598 (32%), Positives = 291/598 (48%), Gaps = 32/598 (5%)

Query: 156  TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTL 215
            +V + ED  +  N  + +++ATDAD G  S + YAI  GN    FSID+ +GD+ LV +L
Sbjct: 679  SVELSEDFPL--NSSVVRLRATDADSGFGSLLVYAISAGNQDGCFSIDTFAGDLRLVCSL 736

Query: 216  DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275
            D E+   Y L I   D G P ++    + + + DVNDN P F    +   V EN  +   
Sbjct: 737  DRERNAFYVLNITVYDLGMPQKTAWRFVAVTVTDVNDNPPEFDQLRYVTRVPENAEVDSV 796

Query: 276  IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL 335
            +    A D D  V   L +++             +IDP +G V     LDRET  ++ L 
Sbjct: 797  VFTAHAADPDLDVGGRLRFSLLTPTNA------FSIDPVTGEVTLKAPLDRETTPRHDLQ 850

Query: 336  VTATDGGD--PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393
            + A DG +  P   +                 F+P  Y++++ ED P GT ++ + + D 
Sbjct: 851  IVAKDGAERGPRLVSVVDLVVVLQDVNDNPPRFLPHNYKIKVPEDLPVGTLLLWVESVDL 910

Query: 394  D--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG---G 448
            D      + Y +      G F + S    G +T+ + LDF++ R Y LTV A D G    
Sbjct: 911  DLASGGLVTYNLKNPE-GGSFRLDSST--GALTLERELDFERRRSYTLTVRAVDHGLPRS 967

Query: 449  RSDTAMVQINITDANN--YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506
             S +  V+I + D N   + P+F    Y A+V EDA +GT+VL ++A+D DVG + +  +
Sbjct: 968  LSSSCFVEIEVLDVNENLHRPLFSEFVYEAAVMEDAAVGTSVLKLTASDKDVGRDGEFRF 1027

Query: 507  SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566
             +  + S   V      F I+ +TG I + K+LDRE M  Y L+V   D G   L   T 
Sbjct: 1028 HI-QDGSGLGV------FSIDEETGVICSAKILDREKMPHYWLSVLVGDLGTEPLLSWTH 1080

Query: 567  VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE 626
            V + V+DVNDN P   Q +Y A++ E+     SV+QV ATDAD    G++ + +    R 
Sbjct: 1081 VFLRVLDVNDNAPQLSQPVYFASVQENVDGVGSVAQVWATDADASSEGKLSFHMLESHRT 1140

Query: 627  EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686
               F +DP +GV+ T  ALDRE    H ++ V  D G+P  SST  V I++ D ND+ P 
Sbjct: 1141 H--FDVDPKTGVVSTLSALDREEKEEHSVEVVVSDNGSPSLSSTTTVVIRVLDDNDNQPK 1198

Query: 687  FESDCLTFYISE--NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
            F        I E   S     +  + A D D G NA V Y ++  D S  F ++   G
Sbjct: 1199 FTDKLFHIKIPEQRRSAGEQEVYRMVARDDDRGSNAAVTYRLQ-DDHSERFKIDPLLG 1255



 Score =  283 bits (693), Expect = 6e-74
 Identities = 230/748 (30%), Positives = 351/748 (46%), Gaps = 69/748 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND+ P+F+   Y A + E   +GTTV+ + A D D   N  V Y++E +  +  
Sbjct: 2730 IQVQDVNDNEPLFDASPYRAFLAENMPAGTTVIQVTANDADSETNGLVTYSLEALPEE-- 2787

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
              E+A            ++F ID  SG + T    D E V  Y   V ATD    +  RL
Sbjct: 2788 EEEEAGAT---------EMFSIDEESGWITTTQEADCEAVRVYRFSVVATDNGGGL--RL 2836

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG-ANSAIRY 189
            SS+  + V + D+NDN P+FS + Y  SV E+ S     V+  +   DADV   N  +  
Sbjct: 2837 SSSVLVEVTVTDENDNPPKFSLEAYRGSVVENSS--PGEVLVSMTTADADVSLENRLVTC 2894

Query: 190  AIIGGNTQMQFSIDSLS-GDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
             I  G+    F+I   S G   L+ T  LD E    + L + A DG   +   +  + ++
Sbjct: 2895 YITDGDPLGHFAIIQQSEGGWGLILTQPLDREVKDRHALRVMATDGKFQA---SVSVDVH 2951

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            + D+NDN+P+    ++ E+V EN P    +++V A D D G N +++Y++    +  N D
Sbjct: 2952 VLDINDNSPQCEQLVYTEAVMENSPSSRFVLKVSAVDPDVGANGQVSYSL----HGPNAD 3007

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
                ++ R+G + T   LDRE + +Y L+  ATDGG   RS  +               F
Sbjct: 3008 -KFHLNYRTGELLTLAVLDREAEPEYNLVAKATDGGG--RSCQSDILLMIQDMNDNPPRF 3064

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
                Y++ + ++    TP+  L A D D             T   FS+   +  GL+ + 
Sbjct: 3065 SSSHYQLTVFDNTTVHTPIAVLYAKDPD-------------TCSFFSLDEFS--GLLRLE 3109

Query: 427  QPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
            +PL       + L V ATD G        A V + +   ++Y PVF ++ YTA + E   
Sbjct: 3110 RPLTPDAPPTFELKVKATDRGLPRHLYSIATVTVAVVSLDDYQPVFLSSEYTAQLPESFA 3169

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
            +G+ VL +SA   D G    + Y + S   NE     D +F+++ +TG +T    LD E 
Sbjct: 3170 VGSQVLSLSALTRDGGGPDPVAYRIVS--GNE-----DGRFLLDSRTGLLTLVAPLDFEA 3222

Query: 544  MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV--- 600
               Y L+V  R  G  +LSD T V ++V DVNDN PVF++  Y   I ED   G+ V   
Sbjct: 3223 SRTYYLSVEGR-RGKQTLSDITTVMVNVTDVNDNAPVFEEGGYRVEIKEDLPPGSLVMKV 3281

Query: 601  ---------SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA 651
                      +V A+D D   N  + Y +   D  +  F I P SG I    ALDRE V 
Sbjct: 3282 PAQEPPVFGGKVTASDQDGPSNSLLRYSIVSGDPLQ-QFSIHPRSGEISVAAALDREEVP 3340

Query: 652  THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711
             + L   A DGG PP SS ++V I + D+ND+PP+F     +  + E  P+G+++ ++  
Sbjct: 3341 HYSLTVQAADGGDPPLSSAILVTITVADVNDNPPIFSRVNHSLLLQEGEPVGSSVLQLVV 3400

Query: 712  HDPDEGPNA-VVHYSIKGGDDSNSFSLE 738
             D D   N     + I  G+    F ++
Sbjct: 3401 TDRDTPRNGPPFSFHIVSGNQERRFHVD 3428



 Score =  278 bits (681), Expect = 2e-72
 Identities = 231/774 (29%), Positives = 365/774 (47%), Gaps = 61/774 (7%)

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDE--DIS--VT---DNPVIAKIKATDADVGA 183
            SS+  + + + D+NDN P F +K Y   + E  DI   VT     P++  I+A+DAD  A
Sbjct: 1683 SSSTFVSIYVTDENDNAPVFRQKEYLGQISEAADIGAMVTGEGSRPLV--IQASDADRDA 1740

Query: 184  NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR--SNTT 241
            N+ + Y I+       FSID   G +SL+  +D+E    YR  ++ +D G P R  +   
Sbjct: 1741 NALLVYQILEPELLSVFSIDPSMGTISLLSAVDFEARAEYRFSVQVRDSGEPCRYAAEPA 1800

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
            ++ + + D+ND AP F + +++ SV      G  +  V A DAD  V     Y++ +   
Sbjct: 1801 KVTVRVLDLNDCAPHFTSPVYESSVILPAVRGMEVTHVTARDADSAV----AYSIVE--- 1853

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
             GN+    +++P SG +  S          YQL++ A+DG        AT          
Sbjct: 1854 -GNLHGAFSVEPSSGLITVSNATG--FTGFYQLVLRASDG---LHQDLATVRVNGSALTG 1907

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421
                F    Y V +AE+      +  L A     +  L + +   N  G+FSI++ +G  
Sbjct: 1908 GHLGFEQDVYTVSVAENLRTVRTLAALKARGCLFNEPLVFSLL--NPEGKFSISASSG-V 1964

Query: 422  LITVAQPLDFKQERRY--VLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479
            L T   P D ++   Y  V+ V  T +  R+  A V++ I D N+  P F N P++  + 
Sbjct: 1965 LETTGIPFDREETDVYEVVVMVRDTRTPPRTARAQVRVFIDDVNDSPPQFSNLPFSIVIP 2024

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
            E +  G  +   SA D D+G NA I YSL  + S          F I+P  G I+  + L
Sbjct: 2025 ESSEPGDVLYQASAVDGDLGENASILYSLEEDYS---------LFRIDPHAGDISLQRPL 2075

Query: 540  DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
            D E ++ Y+LTV A D G PS S T  + + V   N + PVF+  LY   + E+    T+
Sbjct: 2076 DFEALNKYVLTVLAVDEGEPSHSATAQLSLQV--RNQSSPVFQTLLYPLKVPENIPPFTT 2133

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
            +  V A + D     R+ Y L  ++  +  F ID  +GV+     LD ES   H L   A
Sbjct: 2134 ILHVQARNPD---GYRLVYNLQEENASK-HFHIDFKTGVLTVTDPLDYESQRAHVLTVRA 2189

Query: 660  IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
             D  T    S   V I++ED+ND+ PVF        ++E  P+GT++ ++ A D D G N
Sbjct: 2190 SDSVT-GVFSEASVEIEVEDVNDNAPVFSQRAYGAVVAEGLPVGTSVVQVSASDGDSGRN 2248

Query: 720  --AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPL 774
                 H      +++  F ++   G     +VT   LD+E    ++ L IRA    + PL
Sbjct: 2249 RDLTFHMLRTERNETEFFDIDPHTG----VIVTKQVLDHEG-TNQFHLKIRATDNGTAPL 2303

Query: 775  WNDVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYR 830
             ++  V + VTDVNDN P  V   ++   +    C  +    ++ A D D  D  KLQY+
Sbjct: 2304 SSEASVLVNVTDVNDNPPDFVSSQYEATLDEKAKCGHI--VIKIQASDPDSGDLNKLQYK 2361

Query: 831  ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884
            ILSGN      +N+++G ++ S     N+     + V+V+DGV +  A + + +
Sbjct: 2362 ILSGNEGRYFNINQSSGIVSFSNVCRRNLEPFYNLTVAVSDGVFQKTARVNIDM 2415



 Score =  273 bits (670), Expect = 4e-71
 Identities = 247/880 (28%), Positives = 388/880 (44%), Gaps = 73/880 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTV-------LTLKATDQDIGKNAEVEYTIE 63
            I V D ND++PVF  ++Y   + E A  G  V       L ++A+D D   NA + Y I 
Sbjct: 1690 IYVTDENDNAPVFRQKEYLGQISEAADIGAMVTGEGSRPLVIQASDADRDANALLVYQI- 1748

Query: 64   LVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQA 123
                  L PE            +  VF ID   G +   +++D E  A Y   V+  D  
Sbjct: 1749 ------LEPE------------LLSVFSIDPSMGTISLLSAVDFEARAEYRFSVQVRDSG 1790

Query: 124  SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183
             P     +  A + V ++D ND  P F+   Y  SV   +       +  + A DAD   
Sbjct: 1791 EPCR-YAAEPAKVTVRVLDLNDCAPHFTSPVYESSVI--LPAVRGMEVTHVTARDAD--- 1844

Query: 184  NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
             SA+ Y+I+ GN    FS++  SG +++     +     Y+LV+RA DG      +   +
Sbjct: 1845 -SAVAYSIVEGNLHGAFSVEPSSGLITVSNATGFTGF--YQLVLRASDG---LHQDLATV 1898

Query: 244  LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
             +N   +      F   ++  SV+EN+    ++  ++A       N  L +++       
Sbjct: 1899 RVNGSALTGGHLGFEQDVYTVSVAENLRTVRTLAALKARGCL--FNEPLVFSLL------ 1950

Query: 304  NVDLPITIDPRSGWVYTSG-QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
            N +   +I   SG + T+G   DRE    Y+++V   D   PPR+A A            
Sbjct: 1951 NPEGKFSISASSGVLETTGIPFDREETDVYEVVVMVRDTRTPPRTARAQVRVFIDDVNDS 2010

Query: 363  XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422
               F    + + + E   PG  +   +A D D         +       F I    G   
Sbjct: 2011 PPQFSNLPFSIVIPESSEPGDVLYQASAVDGDLGENASILYSLEEDYSLFRIDPHAGD-- 2068

Query: 423  ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
            I++ +PLDF+   +YVLTV A D G  S +A  Q+++   N  +PVF+   Y   V E+ 
Sbjct: 2069 ISLQRPLDFEALNKYVLTVLAVDEGEPSHSATAQLSLQVRNQSSPVFQTLLYPLKVPENI 2128

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
            P  TT+L V A + D     ++ Y+L  E +++        F I+ +TG +T    LD E
Sbjct: 2129 PPFTTILHVQARNPD---GYRLVYNLQEENASK-------HFHIDFKTGVLTVTDPLDYE 2178

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
            +   ++LTV A D  V  +     VEI V DVNDN PVF Q+ Y A + E   VGTSV Q
Sbjct: 2179 SQRAHVLTVRASDS-VTGVFSEASVEIEVEDVNDNAPVFSQRAYGAVVAEGLPVGTSVVQ 2237

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFV-IDPASGVIRTNKALDRESVATHDLKAVAID 661
            V A+D D G N  + + +   +R E  F  IDP +GVI T + LD E      LK  A D
Sbjct: 2238 VSASDGDSGRNRDLTFHMLRTERNETEFFDIDPHTGVIVTKQVLDHEGTNQFHLKIRATD 2297

Query: 662  GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
             GT P SS   V + + D+ND+PP F S      + E +  G  + +I+A DPD G    
Sbjct: 2298 NGTAPLSSEASVLVNVTDVNDNPPDFVSSQYEATLDEKAKCGHIVIKIQASDPDSGDLNK 2357

Query: 722  VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781
            + Y I  G++   F++    G     +V+  ++   +    Y L +  +        RV 
Sbjct: 2358 LQYKILSGNEGRYFNINQSSG-----IVSFSNVCRRNLEPFYNLTVAVSDGVFQKTARVN 2412

Query: 782  ILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILSGNNAN 838
            I +   N ++P  K   +      +   VG    R+ A D D  +   + Y I++   A+
Sbjct: 2413 IDMLSTNKHSPSFKQ-SVYEAELAENAEVGTQVIRLAAIDPDEGLYGSVDYTIIN-KLAD 2470

Query: 839  LILLNETTGSMTLSPQLNTNVP--KLATMEVSVTDGVNEI 876
              L  ++ G M  +  L+   P  ++  ++V   DG  ++
Sbjct: 2471 EKLAIDSDGQMVTTQPLDRENPAQRIIAVKVMAKDGGGKV 2510



 Score =  260 bits (637), Expect = 4e-67
 Identities = 247/897 (27%), Positives = 390/897 (43%), Gaps = 81/897 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I++L  N HSP F+   YEA + E A  GT V+ L A D D G    V+YTI    AD  
Sbjct: 2413 IDMLSTNKHSPSFKQSVYEAELAENAEVGTQVIRLAAIDPDEGLYGSVDYTIINKLAD-- 2470

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                             +   ID   G ++T   LDRE  A+  + VK    A     ++
Sbjct: 2471 -----------------EKLAIDS-DGQMVTTQPLDRENPAQRIIAVKV--MAKDGGGKV 2510

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +   T+ + + D+NDN PQF+   Y VS+   ++   +PV+  I A DAD G N+ + Y 
Sbjct: 2511 AF-CTVRIILTDENDNVPQFAASEYQVSIQSTVN-KGSPVV-HIMAYDADEGRNADVTYT 2567

Query: 191  IIGGN--TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            +      T+    I+  +G V++  +L   + R +   ++A+DG  P  + T  + + + 
Sbjct: 2568 VDEAEEATEDVIEINPFTGLVTVKDSLVGMENRIFNFKVQARDGSLPFYNATVPVQVRVL 2627

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD-YTGNVDL 307
                  P+F   L+  S  E+ P+G  I  V+A       N  L Y++ D +    N D 
Sbjct: 2628 PPEVPLPQFSEPLYTFSAVEDAPVGTEIGSVRAAS-----NTPLIYSLVDGNTLENNKDK 2682

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX-XF 366
              ++D  SG +     +D E    YQ+ V A    +    A+                 F
Sbjct: 2683 VFSLDEDSGTLVLQKPMDHERTKWYQIDVMAQGNHNGTAVASLVSISIQVQDVNDNEPLF 2742

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDAD-EDNRL----------HYEITGGNTRGRFSIT 415
                Y   LAE+ P GT V+ +TA DAD E N L            E   G T   FSI 
Sbjct: 2743 DASPYRAFLAENMPAGTTVIQVTANDADSETNGLVTYSLEALPEEEEEEAGATE-MFSID 2801

Query: 416  SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR---SDTAMVQINITDANNYAPVFENA 472
             ++G   IT  Q  D +  R Y  +V ATD+GG    S + +V++ +TD N+  P F   
Sbjct: 2802 EESG--WITTTQEADCEAVRVYRFSVVATDNGGGLRLSSSVLVEVTVTDENDNPPKFSLE 2859

Query: 473  PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
             Y  SV E++  G  ++ ++  D+DV +  ++     ++   + + H           G 
Sbjct: 2860 AYRGSVVENSSPGEVLVSMTTADADVSLENRLVTCYITD--GDPLGHFAIIQQSEGGWGL 2917

Query: 533  ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592
            I T  L DRE    + L V A DG       +  V++ V+D+NDN P  +Q +YT  +ME
Sbjct: 2918 ILTQPL-DREVKDRHALRVMATDG---KFQASVSVDVHVLDINDNSPQCEQLVYTEAVME 2973

Query: 593  DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652
            ++     V +V A D DVG NG++ Y L   + ++  F ++  +G + T   LDRE+   
Sbjct: 2974 NSPSSRFVLKVSAVDPDVGANGQVSYSLHGPNADK--FHLNYRTGELLTLAVLDREAEPE 3031

Query: 653  HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
            ++L A A DGG     S ++  + I+D+ND+PP F S      + +N+ + T I  + A 
Sbjct: 3032 YNLVAKATDGGGRSCQSDIL--LMIQDMNDNPPRFSSSHYQLTVFDNTTVHTPIAVLYAK 3089

Query: 713  DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP 772
            DPD                 + FSL+   G  + E     D    +   K +   R    
Sbjct: 3090 DPDT---------------CSFFSLDEFSGLLRLERPLTPDAP-PTFELKVKATDRGLPR 3133

Query: 773  PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG---RVPAYDADVTDKLQY 829
             L++   V + V  ++D  PV    +       + F VG           D    D + Y
Sbjct: 3134 HLYSIATVTVAVVSLDDYQPVFLSSEYTAQ-LPESFAVGSQVLSLSALTRDGGGPDPVAY 3192

Query: 830  RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886
            RI+SGN     LL+  TG +TL   L+    +   + V    G   +  +  + V +
Sbjct: 3193 RIVSGNEDGRFLLDSRTGLLTLVAPLDFEASRTYYLSVEGRRGKQTLSDITTVMVNV 3249



 Score =  260 bits (637), Expect = 4e-67
 Identities = 205/664 (30%), Positives = 317/664 (47%), Gaps = 60/664 (9%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ V D ND+ P F ++ Y  SV E +S G  ++++   D D+     +  T  +   D 
Sbjct: 2843 EVTVTDENDNPPKFSLEAYRGSVVENSSPGEVLVSMTTADADVSLENRL-VTCYITDGDP 2901

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            L               +Q   + +G  G +LT+  LDRE   R+ + V ATD       +
Sbjct: 2902 LG----------HFAIIQ---QSEGGWGLILTQP-LDREVKDRHALRVMATD------GK 2941

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
              ++ ++ V+++D NDN PQ  +  YT +V E+     +  + K+ A D DVGAN  + Y
Sbjct: 2942 FQASVSVDVHVLDINDNSPQCEQLVYTEAVMENSP--SSRFVLKVSAVDPDVGANGQVSY 2999

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            ++ G N   +F ++  +G++  +  LD E    Y LV +A DGG   RS  + +L+ I+D
Sbjct: 3000 SLHGPNAD-KFHLNYRTGELLTLAVLDREAEPEYNLVAKATDGGG--RSCQSDILLMIQD 3056

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            +NDN PRF +S +Q +V +N  +   I  + A D D       T +              
Sbjct: 3057 MNDNPPRFSSSHYQLTVFDNTTVHTPIAVLYAKDPD-------TCSF------------F 3097

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRS-ATATXXXXXXXXXXXXXXFMP 368
            ++D  SG +     L  +    ++L V ATD G P    + AT              F+ 
Sbjct: 3098 SLDEFSGLLRLERPLTPDAPPTFELKVKATDRGLPRHLYSIATVTVAVVSLDDYQPVFLS 3157

Query: 369  GQYEVELAEDEPPGTPVVTLTAT--DADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
             +Y  +L E    G+ V++L+A   D    + + Y I  GN  GRF + S+ G  L+T+ 
Sbjct: 3158 SEYTAQLPESFAVGSQVLSLSALTRDGGGPDPVAYRIVSGNEDGRFLLDSRTG--LLTLV 3215

Query: 427  QPLDFKQERRYVLTVSATDSGGR-SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
             PLDF+  R Y L+V         SD   V +N+TD N+ APVFE   Y   + ED P G
Sbjct: 3216 APLDFEASRTYYLSVEGRRGKQTLSDITTVMVNVTDVNDNAPVFEEGGYRVEIKEDLPPG 3275

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNE----AVAHHD--QQFVINPQTGAITTNKLL 539
            + V+ V A +  V    ++T S     SN     ++   D  QQF I+P++G I+    L
Sbjct: 3276 SLVMKVPAQEPPV-FGGKVTASDQDGPSNSLLRYSIVSGDPLQQFSIHPRSGEISVAAAL 3334

Query: 540  DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
            DRE +  Y LTV A DGG P LS    V I+V DVNDN P+F +  ++  + E   VG+S
Sbjct: 3335 DREEVPHYSLTVQAADGGDPPLSSAILVTITVADVNDNPPIFSRVNHSLLLQEGEPVGSS 3394

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
            V Q+  TD D   NG           +E  F +D   G++  +  L ++    H LK + 
Sbjct: 3395 VLQLVVTDRDTPRNGPPFSFHIVSGNQERRFHVD-QGGLLSLSAPLRKKVKGHHQLK-IQ 3452

Query: 660  IDGG 663
            + GG
Sbjct: 3453 VTGG 3456



 Score =  240 bits (587), Expect = 5e-61
 Identities = 229/818 (27%), Positives = 366/818 (44%), Gaps = 78/818 (9%)

Query: 89   VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
            VF +D  SG L+ +  +D E+   Y + V A  Q +     ++S  +I + + D NDN P
Sbjct: 2683 VFSLDEDSGTLVLQKPMDHERTKWYQIDVMA--QGNHNGTAVASLVSISIQVQDVNDNEP 2740

Query: 149  QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG---------GNTQMQ 199
             F    Y   + E++       + ++ A DAD   N  + Y++           G T+M 
Sbjct: 2741 LFDASPYRAFLAENMPA--GTTVIQVTANDADSETNGLVTYSLEALPEEEEEEAGATEM- 2797

Query: 200  FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIRDVNDNAPRFY 258
            FSID  SG ++  +  D E VR YR  + A D G   R +++ L+ + + D NDN P+F 
Sbjct: 2798 FSIDEESGWITTTQEADCEAVRVYRFSVVATDNGGGLRLSSSVLVEVTVTDENDNPPKFS 2857

Query: 259  TSLFQESVSENVPIGYSIVRVQAYDADEGV-NAELTYTMTDKDYTGNVDLPITIDPRSGW 317
               ++ SV EN   G  +V +   DAD  + N  +T  +TD D  G+    I      GW
Sbjct: 2858 LEAYRGSVVENSSPGEVLVSMTTADADVSLENRLVTCYITDGDPLGH--FAIIQQSEGGW 2915

Query: 318  -VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376
             +  +  LDRE + ++ L V ATDG      A+ +                   Y   + 
Sbjct: 2916 GLILTQPLDREVKDRHALRVMATDG---KFQASVSVDVHVLDINDNSPQCEQLVYTEAVM 2972

Query: 377  EDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434
            E+ P    V+ ++A D D   + ++ Y + G N   +F +  + G  L+T+A  LD + E
Sbjct: 2973 ENSPSSRFVLKVSAVDPDVGANGQVSYSLHGPNA-DKFHLNYRTGE-LLTLAV-LDREAE 3029

Query: 435  RRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494
              Y L   ATD GGRS  + + + I D N+  P F ++ Y  +VF++  + T + V+ A 
Sbjct: 3030 PEYNLVAKATDGGGRSCQSDILLMIQDMNDNPPRFSSSHYQLTVFDNTTVHTPIAVLYAK 3089

Query: 495  DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554
            D D       T S                F ++  +G +   + L  +    + L V A 
Sbjct: 3090 DPD-------TCSF---------------FSLDEFSGLLRLERPLTPDAPPTFELKVKAT 3127

Query: 555  DGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613
            D G+P  L     V ++VV ++D +PVF    YTA + E   VG+ V  + A   D G  
Sbjct: 3128 DRGLPRHLYSIATVTVAVVSLDDYQPVFLSSEYTAQLPESFAVGSQVLSLSALTRDGGGP 3187

Query: 614  GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673
              + Y +     E+G F++D  +G++     LD E+  T+ L +V    G    S    V
Sbjct: 3188 DPVAYRI-VSGNEDGRFLLDSRTGLLTLVAPLDFEASRTYYL-SVEGRRGKQTLSDITTV 3245

Query: 674  HIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP-----------DEGP-NAV 721
             + + D+ND+ PVFE       I E+ P G+ + ++ A +P            +GP N++
Sbjct: 3246 MVNVTDVNDNAPVFEEGGYRVEIKEDLPPGSLVMKVPAQEPPVFGGKVTASDQDGPSNSL 3305

Query: 722  VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDV 778
            + YSI  GD    FS+  R G    E+     LD E     Y L ++AA    PPL + +
Sbjct: 3306 LRYSIVSGDPLQQFSIHPRSG----EISVAAALDREEV-PHYSLTVQAADGGDPPLSSAI 3360

Query: 779  RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVT---DKLQYRILSG 834
             V I V DVNDN P+           ++  PVG    ++   D D         + I+SG
Sbjct: 3361 LVTITVADVNDNPPIFSRVNHSL-LLQEGEPVGSSVLQLVVTDRDTPRNGPPFSFHIVSG 3419

Query: 835  NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            N      +++  G ++LS  L   V     +++ VT G
Sbjct: 3420 NQERRFHVDQ-GGLLSLSAPLRKKVKGHHQLKIQVTGG 3456



 Score =  238 bits (583), Expect = 1e-60
 Identities = 208/709 (29%), Positives = 319/709 (44%), Gaps = 62/709 (8%)

Query: 17   NDHSPVFE-MQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDA 75
            N HSP F+ +      + E     ++V+ L+ATD D G  + + Y I     D       
Sbjct: 666  NRHSPKFDPVLPSSVELSEDFPLNSSVVRLRATDADSGFGSLLVYAISAGNQD------- 718

Query: 76   XXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTAT 135
                          F ID  +G L    SLDRE+ A Y + +   D   P   + ++   
Sbjct: 719  ------------GCFSIDTFAGDLRLVCSLDRERNAFYVLNITVYDLGMP---QKTAWRF 763

Query: 136  IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195
            + V + D NDN P+F +  Y   V E+  V  + V+    A D D+     +R++++   
Sbjct: 764  VAVTVTDVNDNPPEFDQLRYVTRVPENAEV--DSVVFTAHAADPDLDVGGRLRFSLL--T 819

Query: 196  TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG--SPSRSNTTQLLINIRDVNDN 253
                FSID ++G+V+L   LD E    + L I A+DG    P   +   L++ ++DVNDN
Sbjct: 820  PTNAFSIDPVTGEVTLKAPLDRETTPRHDLQIVAKDGAERGPRLVSVVDLVVVLQDVNDN 879

Query: 254  APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313
             PRF    ++  V E++P+G  ++ V++ D D      +TY +  K+  G       +D 
Sbjct: 880  PPRFLPHNYKIKVPEDLPVGTLLLWVESVDLDLASGGLVTYNL--KNPEGG---SFRLDS 934

Query: 314  RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP----G 369
             +G +    +LD E +  Y L V A D G  PRS +++                P     
Sbjct: 935  STGALTLERELDFERRRSYTLTVRAVDHG-LPRSLSSSCFVEIEVLDVNENLHRPLFSEF 993

Query: 370  QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
             YE  + ED   GT V+ LTA+D D   D    + I  G+  G FSI  +   G+I  A+
Sbjct: 994  VYEAAVMEDAAVGTSVLKLTASDKDVGRDGEFRFHIQDGSGLGVFSIDEET--GVICSAK 1051

Query: 428  PLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
             LD ++   Y L+V   D G         V + + D N+ AP      Y ASV E+    
Sbjct: 1052 ILDREKMPHYWLSVLVGDLGTEPLLSWTHVFLRVLDVNDNAPQLSQPVYFASVQENVDGV 1111

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
             +V  V ATD+D     ++++ +        +  H   F ++P+TG ++T   LDRE   
Sbjct: 1112 GSVAQVWATDADASSEGKLSFHM--------LESHRTHFDVDPKTGVVSTLSALDREEKE 1163

Query: 546  GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED--ALVGTSVSQV 603
             + + V   D G PSLS TT V I V+D NDN+P F  +L+   I E   +     V ++
Sbjct: 1164 EHSVEVVVSDNGSPSLSSTTTVVIRVLDDNDNQPKFTDKLFHIKIPEQRRSAGEQEVYRM 1223

Query: 604  GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
             A D D G N  + Y L  +D     F IDP  GV+         + +   +KA   D G
Sbjct: 1224 VARDDDRGSNAAVTYRL--QDDHSERFKIDPLLGVVTARGDFWPGNYSILTVKAT--DQG 1279

Query: 664  TPPQSSTV---IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
            +PP+SST    +  I +   +D P  FE    TF + E  P+   +G I
Sbjct: 1280 SPPRSSTARLDVEWIALPPPSDEPISFEEPHFTFAVMETEPVTHMVGII 1328



 Score =  206 bits (503), Expect = 7e-51
 Identities = 171/563 (30%), Positives = 261/563 (46%), Gaps = 34/563 (6%)

Query: 246  NIRDVNDNAPRFYTSLFQE-SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
            ++   N ++P+F   L     +SE+ P+  S+VR++A DAD G  + L Y ++     GN
Sbjct: 661  DVHVTNRHSPKFDPVLPSSVELSEDFPLNSSVVRLRATDADSGFGSLLVYAIS----AGN 716

Query: 305  VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
             D   +ID  +G +     LDRE  A Y L +T  D G P ++A                
Sbjct: 717  QDGCFSIDTFAGDLRLVCSLDRERNAFYVLNITVYDLGMPQKTAWRFVAVTVTDVNDNPP 776

Query: 365  XFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGL 422
             F   +Y   + E+    + V T  A D D D   RL + +        FSI    G   
Sbjct: 777  EFDQLRYVTRVPENAEVDSVVFTAHAADPDLDVGGRLRFSLL--TPTNAFSIDPVTGE-- 832

Query: 423  ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT----DANNYAPVFENAPYTASV 478
            +T+  PLD +   R+ L + A D   R    +  +++     D N+  P F    Y   V
Sbjct: 833  VTLKAPLDRETTPRHDLQIVAKDGAERGPRLVSVVDLVVVLQDVNDNPPRFLPHNYKIKV 892

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             ED P+GT +L V + D D+     +TY+L +             F ++  TGA+T  + 
Sbjct: 893  PEDLPVGTLLLWVESVDLDLASGGLVTYNLKNPEGGS--------FRLDSSTGALTLERE 944

Query: 539  LDRETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDN--EPVFKQQLYTANIMEDAL 595
            LD E    Y LTV A D G+P SLS +  VEI V+DVN+N   P+F + +Y A +MEDA 
Sbjct: 945  LDFERRRSYTLTVRAVDHGLPRSLSSSCFVEIEVLDVNENLHRPLFSEFVYEAAVMEDAA 1004

Query: 596  VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655
            VGTSV ++ A+D DVG +G   + +       G F ID  +GVI + K LDRE +  + L
Sbjct: 1005 VGTSVLKLTASDKDVGRDGEFRFHIQDGSGL-GVFSIDEETGVICSAKILDREKMPHYWL 1063

Query: 656  KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
              +  D GT P  S   V +++ D+ND+ P          + EN     ++ ++ A D D
Sbjct: 1064 SVLVGDLGTEPLLSWTHVFLRVLDVNDNAPQLSQPVYFASVQENVDGVGSVAQVWATDAD 1123

Query: 716  EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIRA-ASPP 773
                  + + +     ++ F ++ + G     + T+  LD E   +   E+V+    SP 
Sbjct: 1124 ASSEGKLSFHMLESHRTH-FDVDPKTGV----VSTLSALDREEKEEHSVEVVVSDNGSPS 1178

Query: 774  LWNDVRVEILVTDVNDNAPVMKD 796
            L +   V I V D NDN P   D
Sbjct: 1179 LSSTTTVVIRVLDDNDNQPKFTD 1201



 Score =  197 bits (480), Expect = 4e-48
 Identities = 239/910 (26%), Positives = 402/910 (44%), Gaps = 101/910 (11%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + VLD ND  P+F    Y  S+ E A   ++V+T+ ATD D+G NA+  Y+         
Sbjct: 104 VRVLDANDLKPLFYPASYSVSIAEDAELRSSVVTVSATDADVGSNADFYYSF----TSRA 159

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS--D 128
           +P                 F +D  +G +     L+  +  RY + V A D+   +S   
Sbjct: 160 HP-----------------FAVDPFTGTVSLVRKLNHTRSQRYELTVLAEDRTKKISGVQ 202

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
           +  + A I V++   +   P  S+ +  V V  D  VT   V  +++A    VG+ S + 
Sbjct: 203 KFGNVAKITVHVQKTSKASPVISQVSKPV-VSADGKVT---VDVQVEAGVKPVGSLSVVG 258

Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGGSPSRSNTTQLLINI 247
             + G  T +          V   K +D+ Q  S + L ++A+D   PS S++ Q  ++I
Sbjct: 259 GDLCGCFTVIPSGAQGDRFQVISTKRIDWPQAPSGFNLSLQARDTSFPSLSSSVQQ-VHI 317

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
                +   F  S ++ ++SE  P    ++ V    + E  NA  ++++ D D  G    
Sbjct: 318 AAAQISPLAFKESTYRVTLSEFSPPNTHVLLVSL--SSEAHNA--SFSIKD-DPDG---A 369

Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
           P  I+P +G + T+ +LD E++ +YQ  V A +GG+    A A               F 
Sbjct: 370 PFRINPLTGVIVTTQKLDYESKRRYQFDVAA-NGGE----AEARVVIEVKDENDNSPQFA 424

Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
              YE  L E+ P G+ V+ ++ATDAD            N+ G    T     G+I+ + 
Sbjct: 425 SPSYEASLDENAPVGSSVLQVSATDADGGKNAFVTYALANS-GPSPFTIHPFTGVISTSG 483

Query: 428 PLDFK-QERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
            LD++   RRY L V A+DSG    R     V I + + N+  P+ E      ++  DAP
Sbjct: 484 HLDYELMRRRYHLRVWASDSGSPFSRVSECPVTITLNNVNDNIPLLERVGCNTTLPVDAP 543

Query: 484 IGTTVLVVSATDSDV----------GINAQI--TYSLSSEIS-NEAVAHHDQQFVINPQT 530
           +G TV+ +SA D D           G   Q+    S+S  IS   A+   +  F ++   
Sbjct: 544 VGGTVVQLSAIDPDELQQLRYLIQSGNELQVFAVDSVSGVISLKRAIPPSEGSFTLSVAA 603

Query: 531 --GAITTNKLLDRETMS--GYLLTVTARDGGV-------------PSLSDTTDVEISVVD 573
             G   +   + R T++  G   TV  ++ G+             P L+   D     V 
Sbjct: 604 TDGRHQSEAAVVRVTVTHRGEEATVACQETGISKQLTARLIQSMEPFLAQEEDEAFPDVH 663

Query: 574 V-NDNEPVFKQQLYTA-NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631
           V N + P F   L ++  + ED  + +SV ++ ATDAD G    + Y +   + ++G F 
Sbjct: 664 VTNRHSPKFDPVLPSSVELSEDFPLNSSVVRLRATDADSGFGSLLVYAISAGN-QDGCFS 722

Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691
           ID  +G +R   +LDRE  A + L     D G P +++   V + + D+ND+PP F+   
Sbjct: 723 IDTFAGDLRLVCSLDRERNAFYVLNITVYDLGMPQKTAWRFVAVTVTDVNDNPPEFDQLR 782

Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751
               + EN+ + + +    A DPD      + +S+     +N+FS++   G    E+   
Sbjct: 783 YVTRVPENAEVDSVVFTAHAADPDLDVGGRLRFSLL--TPTNAFSIDPVTG----EVTLK 836

Query: 752 VDLDYE-SPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYK-- 805
             LD E +PR   ++V +  +   P L + V + +++ DVNDN P     + + +NYK  
Sbjct: 837 APLDRETTPRHDLQIVAKDGAERGPRLVSVVDLVVVLQDVNDNPP-----RFLPHNYKIK 891

Query: 806 --DCFPVGPFGR-VPAYDADV-TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPK 861
             +  PVG     V + D D+ +  L    L         L+ +TG++TL  +L+    +
Sbjct: 892 VPEDLPVGTLLLWVESVDLDLASGGLVTYNLKNPEGGSFRLDSSTGALTLERELDFERRR 951

Query: 862 LATMEVSVTD 871
             T+ V   D
Sbjct: 952 SYTLTVRAVD 961



 Score =  195 bits (475), Expect = 2e-47
 Identities = 156/531 (29%), Positives = 255/531 (48%), Gaps = 32/531 (6%)

Query: 373  VELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
            VEL+ED P  + VV L ATDAD    + L Y I+ GN  G FSI +  G   + +   LD
Sbjct: 680  VELSEDFPLNSSVVRLRATDADSGFGSLLVYAISAGNQDGCFSIDTFAGD--LRLVCSLD 737

Query: 431  FKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
             ++   YVL ++  D G    TA   V + +TD N+  P F+   Y   V E+A + + V
Sbjct: 738  RERNAFYVLNITVYDLGMPQKTAWRFVAVTVTDVNDNPPEFDQLRYVTRVPENAEVDSVV 797

Query: 489  LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
                A D D+ +  ++ +SL +  +          F I+P TG +T    LDRET   + 
Sbjct: 798  FTAHAADPDLDVGGRLRFSLLTPTN---------AFSIDPVTGEVTLKAPLDRETTPRHD 848

Query: 549  LTVTARDGGV--PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
            L + A+DG    P L    D+ + + DVNDN P F    Y   + ED  VGT +  V + 
Sbjct: 849  LQIVAKDGAERGPRLVSVVDLVVVLQDVNDNPPRFLPHNYKIKVPEDLPVGTLLLWVESV 908

Query: 607  DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
            D D+   G + Y L  K+ E GSF +D ++G +   + LD E   ++ L   A+D G P 
Sbjct: 909  DLDLASGGLVTYNL--KNPEGGSFRLDSSTGALTLERELDFERRRSYTLTVRAVDHGLPR 966

Query: 667  Q-SSTVIVHIKIEDINDS--PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
              SS+  V I++ D+N++   P+F        + E++ +GT++ ++ A D D G +    
Sbjct: 967  SLSSSCFVEIEVLDVNENLHRPLFSEFVYEAAVMEDAAVGTSVLKLTASDKDVGRDGEFR 1026

Query: 724  YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY--ELVIRAASPPLWNDVRVE 781
            + I+ G     FS++   G     + +   LD E     +   LV    + PL +   V 
Sbjct: 1027 FHIQDGSGLGVFSIDEETGV----ICSAKILDREKMPHYWLSVLVGDLGTEPLLSWTHVF 1082

Query: 782  ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGNNANL 839
            + V DVNDNAP +       +  ++   VG   +V A DAD +   KL + +L  +  + 
Sbjct: 1083 LRVLDVNDNAPQLSQPVYFASVQENVDGVGSVAQVWATDADASSEGKLSFHMLESHRTHF 1142

Query: 840  ILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITE 889
              ++  TG ++    L+    +  ++EV V+D G   + +   + +R++ +
Sbjct: 1143 D-VDPKTGVVSTLSALDREEKEEHSVEVVVSDNGSPSLSSTTTVVIRVLDD 1192



 Score =  190 bits (463), Expect = 5e-46
 Identities = 188/663 (28%), Positives = 308/663 (46%), Gaps = 54/663 (8%)

Query: 23  FEMQQYEASVREGASSGTTVLTLKATDQDIG-KNAEVEYTIELVTADTLNPEDAXXXXXX 81
           F    YEAS++E +   T V T   T   +   + E++Y++     D L   +A      
Sbjct: 1   FTQPVYEASIKENSPPRTYVETPAKTGIQLSLPHWELDYSVVSGDDDDLFQAEALKVGDF 60

Query: 82  XXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNII 141
                    R+  RSG     A L+RE    YT+ V+AT+++S     L +   + V ++
Sbjct: 61  CF------LRVRTRSG---NAALLNREVRDAYTLTVEATEKSSD----LRAKTKVLVRVL 107

Query: 142 DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFS 201
           D ND  P F   +Y+VS+ ED  +  +  +  + ATDADVG+N+   Y+    +    F+
Sbjct: 108 DANDLKPLFYPASYSVSIAEDAELRSS--VVTVSATDADVGSNADFYYSFT--SRAHPFA 163

Query: 202 IDSLSGDVSLVKTLDYEQVRSYRLVIRAQD-----GGSPSRSNTTQLLINIRDVNDNAPR 256
           +D  +G VSLV+ L++ + + Y L + A+D      G     N  ++ ++++  +  +P 
Sbjct: 164 VDPFTGTVSLVRKLNHTRSQRYELTVLAEDRTKKISGVQKFGNVAKITVHVQKTSKASP- 222

Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD-LPITIDPRS 315
             + + +  VS +   G   V VQ    + GV    + ++   D  G    +P       
Sbjct: 223 VISQVSKPVVSAD---GKVTVDVQV---EAGVKPVGSLSVVGGDLCGCFTVIPSGAQGDR 276

Query: 316 GWVYTSGQLD-RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374
             V ++ ++D  +  + + L + A D   P  S++                F    Y V 
Sbjct: 277 FQVISTKRIDWPQAPSGFNLSLQARDTSFPSLSSSVQQVHIAAAQISPLA-FKESTYRVT 335

Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434
           L+E  PP T V+ ++ +   E +   + I        F I    G  +I   Q LD++ +
Sbjct: 336 LSEFSPPNTHVLLVSLSS--EAHNASFSIKDDPDGAPFRINPLTG--VIVTTQKLDYESK 391

Query: 435 RRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494
           RRY   V+A  +GG ++ A V I + D N+ +P F +  Y AS+ E+AP+G++VL VSAT
Sbjct: 392 RRYQFDVAA--NGGEAE-ARVVIEVKDENDNSPQFASPSYEASLDENAPVGSSVLQVSAT 448

Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM-SGYLLTVTA 553
           D+D G NA +TY+L++             F I+P TG I+T+  LD E M   Y L V A
Sbjct: 449 DADGGKNAFVTYALANS--------GPSPFTIHPFTGVISTSGHLDYELMRRRYHLRVWA 500

Query: 554 RDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612
            D G P S      V I++ +VNDN P+ ++      +  DA VG +V Q+ A D D   
Sbjct: 501 SDSGSPFSRVSECPVTITLNNVNDNIPLLERVGCNTTLPVDAPVGGTVVQLSAIDPDE-- 558

Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672
             ++ Y L     E   F +D  SGVI   +A+   S  +  L   A DG    +++ V 
Sbjct: 559 LQQLRY-LIQSGNELQVFAVDSVSGVISLKRAIP-PSEGSFTLSVAATDGRHQSEAAVVR 616

Query: 673 VHI 675
           V +
Sbjct: 617 VTV 619



 Score =  170 bits (414), Expect = 4e-40
 Identities = 153/543 (28%), Positives = 248/543 (45%), Gaps = 47/543 (8%)

Query: 15   DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
            D ND+ P F    Y+  V E    GT +L +++ D D+     V Y ++       NPE 
Sbjct: 875  DVNDNPPRFLPHNYKIKVPEDLPVGTLLLWVESVDLDLASGGLVTYNLK-------NPEG 927

Query: 75   AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134
                           FR+D  +GAL     LD E+   YT+ V+A D   P S  LSS+ 
Sbjct: 928  GS-------------FRLDSSTGALTLERELDFERRRSYTLTVRAVDHGLPRS--LSSSC 972

Query: 135  TIHVNIIDDNDNY--PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192
             + + ++D N+N   P FSE  Y  +V ED +V  +  + K+ A+D DVG +   R+ I 
Sbjct: 973  FVEIEVLDVNENLHRPLFSEFVYEAAVMEDAAVGTS--VLKLTASDKDVGRDGEFRFHIQ 1030

Query: 193  GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252
             G+    FSID  +G +   K LD E++  Y L +   D G+    + T + + + DVND
Sbjct: 1031 DGSGLGVFSIDEETGVICSAKILDREKMPHYWLSVLVGDLGTEPLLSWTHVFLRVLDVND 1090

Query: 253  NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312
            NAP+    ++  SV ENV    S+ +V A DAD     +L++ M +   T        +D
Sbjct: 1091 NAPQLSQPVYFASVQENVDGVGSVAQVWATDADASSEGKLSFHMLESHRT-----HFDVD 1145

Query: 313  PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE 372
            P++G V T   LDRE + ++ + V  +D G P  S+T T              F    + 
Sbjct: 1146 PKTGVVSTLSALDREEKEEHSVEVVVSDNGSPSLSSTTTVVIRVLDDNDNQPKFTDKLFH 1205

Query: 373  VELAEDEPPG--TPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQP 428
            +++ E         V  + A D D  +   + Y +   ++  RF I      G++T    
Sbjct: 1206 IKIPEQRRSAGEQEVYRMVARDDDRGSNAAVTYRLQDDHSE-RFKIDPL--LGVVTARG- 1261

Query: 429  LDFKQERRYVLTVSATDSGG--RSDTAMVQIN---ITDANNYAPVFENAPYTASVFEDAP 483
             DF      +LTV ATD G   RS TA + +    +   ++    FE   +T +V E  P
Sbjct: 1262 -DFWPGNYSILTVKATDQGSPPRSSTARLDVEWIALPPPSDEPISFEEPHFTFAVMETEP 1320

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
            + T ++ +  T++   +   IT + S +++  A A      + +   G ++T+ LL+ + 
Sbjct: 1321 V-THMVGIIMTETYGQMWYSITAATSLQVALLASAPPAPPPLSSGLLGLLSTH-LLEEDP 1378

Query: 544  MSG 546
             SG
Sbjct: 1379 HSG 1381



 Score =  160 bits (389), Expect = 4e-37
 Identities = 121/408 (29%), Positives = 199/408 (48%), Gaps = 29/408 (7%)

Query: 451  DTAMVQINITDANNYAPVFENA-PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509
            D A   +++T  N ++P F+   P +  + ED P+ ++V+ + ATD+D G  + + Y++S
Sbjct: 656  DEAFPDVHVT--NRHSPKFDPVLPSSVELSEDFPLNSSVVRLRATDADSGFGSLLVYAIS 713

Query: 510  SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569
            +        + D  F I+   G +     LDRE  + Y+L +T  D G+P  +    V +
Sbjct: 714  A-------GNQDGCFSIDTFAGDLRLVCSLDRERNAFYVLNITVYDLGMPQKTAWRFVAV 766

Query: 570  SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629
            +V DVNDN P F Q  Y   + E+A V + V    A D D+ + GR+ + L        +
Sbjct: 767  TVTDVNDNPPEFDQLRYVTRVPENAEVDSVVFTAHAADPDLDVGGRLRFSL---LTPTNA 823

Query: 630  FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT--PPQSSTVIVHIKIEDINDSPPVF 687
            F IDP +G +     LDRE+   HDL+ VA DG    P   S V + + ++D+ND+PP F
Sbjct: 824  FSIDPVTGEVTLKAPLDRETTPRHDLQIVAKDGAERGPRLVSVVDLVVVLQDVNDNPPRF 883

Query: 688  ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747
                    + E+ P+GT +  + + D D     +V Y++K   +  SF L++  G+    
Sbjct: 884  LPHNYKIKVPEDLPVGTLLLWVESVDLDLASGGLVTYNLK-NPEGGSFRLDSSTGA---- 938

Query: 748  LVTMVDLDYESPRKKYELVIRAASPPLWNDVR----VEILVTDVNDN--APVMKDFQIIF 801
            L    +LD+E  R+ Y L +RA    L   +     VEI V DVN+N   P+  +F    
Sbjct: 939  LTLERELDFER-RRSYTLTVRAVDHGLPRSLSSSCFVEIEVLDVNENLHRPLFSEFVYEA 997

Query: 802  NNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTG 847
               +D        ++ A D DV    + ++ I  G+   +  ++E TG
Sbjct: 998  AVMEDAAVGTSVLKLTASDKDVGRDGEFRFHIQDGSGLGVFSIDEETG 1045



 Score =  140 bits (339), Expect = 5e-31
 Identities = 146/566 (25%), Positives = 251/566 (44%), Gaps = 39/566 (6%)

Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383
           L+RE +  Y L V AT+     R+ T                F P  Y V +AED    +
Sbjct: 75  LNREVRDAYTLTVEATEKSSDLRAKTKVLVRVLDANDLKPL-FYPASYSVSIAEDAELRS 133

Query: 384 PVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443
            VVT++ATDAD  +   +  +  +    F++    G   +++ + L+  + +RY LTV A
Sbjct: 134 SVVTVSATDADVGSNADFYYSFTSRAHPFAVDPFTGT--VSLVRKLNHTRSQRYELTVLA 191

Query: 444 TD-----SGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496
            D     SG +   + A + +++   +  +PV         V  D  + T  + V A   
Sbjct: 192 EDRTKKISGVQKFGNVAKITVHVQKTSKASPVISQVSKPV-VSADGKV-TVDVQVEAGVK 249

Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556
            VG  + +   L    +         +F +      I+T ++   +  SG+ L++ ARD 
Sbjct: 250 PVGSLSVVGGDLCGCFTVIPSGAQGDRFQV------ISTKRIDWPQAPSGFNLSLQARDT 303

Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616
             PSLS +   ++ +     +   FK+  Y   + E +   T V  V  +      N   
Sbjct: 304 SFPSLSSSVQ-QVHIAAAQISPLAFKESTYRVTLSEFSPPNTHVLLVSLSSE--AHNASF 360

Query: 617 HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676
             + DP   +   F I+P +GVI T + LD ES   +    VA +GG     + V++ +K
Sbjct: 361 SIKDDP---DGAPFRINPLTGVIVTTQKLDYESKRRYQFD-VAANGGEA--EARVVIEVK 414

Query: 677 IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736
             D ND+ P F S      + EN+P+G+++ ++ A D D G NA V Y++     S  F+
Sbjct: 415 --DENDNSPQFASPSYEASLDENAPVGSSVLQVSATDADGGKNAFVTYALANSGPS-PFT 471

Query: 737 LETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SP-PLWNDVRVEILVTDVNDNAP 792
           +    G     + T   LDYE  R++Y L + A+   SP    ++  V I + +VNDN P
Sbjct: 472 IHPFTG----VISTSGHLDYELMRRRYHLRVWASDSGSPFSRVSECPVTITLNNVNDNIP 527

Query: 793 VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLS 852
           +++          D    G   ++ A D D   +L+Y I SGN   +  ++  +G ++L 
Sbjct: 528 LLERVGCNTTLPVDAPVGGTVVQLSAIDPDELQQLRYLIQSGNELQVFAVDSVSGVISLK 587

Query: 853 PQLNTNVPKLATMEVSVTDGVNEIKA 878
             +  +     T+ V+ TDG ++ +A
Sbjct: 588 RAIPPSEGSF-TLSVAATDGRHQSEA 612



 Score =  109 bits (263), Expect = 8e-22
 Identities = 115/461 (24%), Positives = 195/461 (42%), Gaps = 38/461 (8%)

Query: 439  LTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV-------LVV 491
            L VSA+  GG S +  V I +TD N+ APVF    Y   + E A IG  V       LV+
Sbjct: 1672 LEVSASTVGGASSSTFVSIYVTDENDNAPVFRQKEYLGQISEAADIGAMVTGEGSRPLVI 1731

Query: 492  SATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTV 551
             A+D+D   NA + Y +   +  E ++     F I+P  G I+    +D E  + Y  +V
Sbjct: 1732 QASDADRDANALLVYQI---LEPELLS----VFSIDPSMGTISLLSAVDFEARAEYRFSV 1784

Query: 552  TARDGGVPS--LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
              RD G P    ++   V + V+D+ND  P F   +Y ++++  A+ G  V+ V A DAD
Sbjct: 1785 QVRDSGEPCRYAAEPAKVTVRVLDLNDCAPHFTSPVYESSVILPAVRGMEVTHVTARDAD 1844

Query: 610  VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669
                  + Y +  +    G+F ++P+SG+I  + A        + L   A DG       
Sbjct: 1845 ----SAVAYSI-VEGNLHGAFSVEPSSGLITVSNATG--FTGFYQLVLRASDG---LHQD 1894

Query: 670  TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729
               V +    +      FE D  T  ++EN     T+  ++A       N  + +S+   
Sbjct: 1895 LATVRVNGSALTGGHLGFEQDVYTVSVAENLRTVRTLAALKARGCLF--NEPLVFSLL-- 1950

Query: 730  DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR---AASPPLWNDVRVEILVTD 786
            +    FS+    G  +    T +  D E     YE+V+      +PP     +V + + D
Sbjct: 1951 NPEGKFSISASSGVLE---TTGIPFDREE-TDVYEVVVMVRDTRTPPRTARAQVRVFIDD 2006

Query: 787  VNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETT 846
            VND+ P   +        +   P     +  A D D+ +          + +L  ++   
Sbjct: 2007 VNDSPPQFSNLPFSIVIPESSEPGDVLYQASAVDGDLGENASILYSLEEDYSLFRIDPHA 2066

Query: 847  GSMTLSPQLNTN-VPKLATMEVSVTDGVNEIKAMMQLSVRL 886
            G ++L   L+   + K     ++V +G     A  QLS+++
Sbjct: 2067 GDISLQRPLDFEALNKYVLTVLAVDEGEPSHSATAQLSLQV 2107



 Score = 38.3 bits (85), Expect = 3.0
 Identities = 47/199 (23%), Positives = 91/199 (45%), Gaps = 18/199 (9%)

Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGL-NGRIHYEL---DPKD--REEGSFVIDP 634
           F Q +Y A+I E++   T V     T   + L +  + Y +   D  D  + E   V D 
Sbjct: 1   FTQPVYEASIKENSPPRTYVETPAKTGIQLSLPHWELDYSVVSGDDDDLFQAEALKVGDF 60

Query: 635 ASGVIRTNKA----LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690
               +RT       L+RE    + L   A +  +  ++ T ++ +++ D ND  P+F   
Sbjct: 61  CFLRVRTRSGNAALLNREVRDAYTLTVEATEKSSDLRAKTKVL-VRVLDANDLKPLFYPA 119

Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750
             +  I+E++ + +++  + A D D G NA  +YS      ++ F+++   G+     V+
Sbjct: 120 SYSVSIAEDAELRSSVVTVSATDADVGSNADFYYSFT--SRAHPFAVDPFTGT-----VS 172

Query: 751 MVDLDYESPRKKYELVIRA 769
           +V     +  ++YEL + A
Sbjct: 173 LVRKLNHTRSQRYELTVLA 191


>UniRef50_UPI000155CE87 Cluster: PREDICTED: similar to FAT tumor
            suppressor homolog 4 (Drosophila); n=1; Ornithorhynchus
            anatinus|Rep: PREDICTED: similar to FAT tumor suppressor
            homolog 4 (Drosophila) - Ornithorhynchus anatinus
          Length = 1683

 Score =  311 bits (764), Expect = 2e-82
 Identities = 305/1104 (27%), Positives = 476/1104 (43%), Gaps = 103/1104 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQ-DIGKNAEVEYTIELVTADT 69
            ++V+D NDH P F    Y   V +  S GT V+ + A D  D G N+ VEY   L+T   
Sbjct: 573  VHVVDGNDHPPRFLSAGYSTPVPKDVSVGTRVIQVAAADDGDFGLNSRVEY---LLTGQ- 628

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
               E A              F +D  +G +   A L  +    + + V A D   P    
Sbjct: 629  ---EPAAR------------FGLDAETGWVSVAAPLTGDVDRTFRLSVTARDGGRPP--- 670

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISV--------------TDNPV----- 170
            LS+ AT+ + + + N + P+F      V V E ++V               +N +     
Sbjct: 671  LSAGATVRILVTEANAHTPEFPRDRVRVEVPETLAVGAVVCVLAARDSDPAENGLLFYAF 730

Query: 171  -----IAKIKATDA-DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR 224
                 ++ + A D  +V   S + Y + G     +F +D+ +G VS+   L  +  R++R
Sbjct: 731  PPGTGVSYLAAEDEQEVSIKSRVEYLLTGQEPAARFGLDAETGWVSVAAPLTGDVDRTFR 790

Query: 225  LVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA 284
            L + A+DGG P  S    + I + + N + P F     +  V E + +G  +  + A DA
Sbjct: 791  LSVTARDGGRPPLSAGATVRILVTEANAHTPEFPRDRVRVEVPETLAVGAVVCVLAARDA 850

Query: 285  DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP 344
            D   N  L Y ++     GN +    ++  +G +  +G LD ET   +++ V+ATDGG  
Sbjct: 851  DPAENGLLAYAVS----AGNGEGLFAVNASTGVLTLAGALDYETGRSHEVTVSATDGGWA 906

Query: 345  PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT 404
             R+                  F   +Y  E+AE+ P GTPVVTL ATDAD          
Sbjct: 907  ARTGFCAVTVDVLDVNDNPPVFAGAEYTPEVAENAPSGTPVVTLRATDADSGPNAVVAYA 966

Query: 405  GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA--TDSGGRSDTAMVQINITDA 462
                 G       N  G+++    LD++  R + LTV A       R   A V + +T  
Sbjct: 967  LHEADGDLFAVDPN-TGVVSTQGFLDYETRREHRLTVKAFNVPDEERCAFAAVTVRVTGV 1025

Query: 463  NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522
            N Y P F +A Y   V E AP GT V  V A D D G + +++Y L  E   +       
Sbjct: 1026 NEYIPRFVSAAYGFEVSEAAPPGTPVGQVFAGDRDRGPDGEVSYLLFGESRRKG------ 1079

Query: 523  QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD--VEISVVDVNDNEPV 580
             F +  +TG I+    LDRE      L V A++ G    +D  +  V ++V+D ND  PV
Sbjct: 1080 -FRVERETGQISVAGPLDREREGTVALRVLAKNAGPIRGADVDEVAVNVTVLDAND-PPV 1137

Query: 581  FKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVI 639
            F  + Y   I E    GT V+ VGA DAD V    R  Y + P   +  +F + P +G +
Sbjct: 1138 FGAETYRVRISEGVPPGTHVTFVGAADADSVPAWSRFSYRVGPAGGD--AFSVHPQTGQV 1195

Query: 640  RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699
                 LDRE++  ++L  +A+D GTPP +   ++ + +ED+ND+ PV         ++EN
Sbjct: 1196 TVTAPLDRETLPVYNLTVLAVDTGTPPATGRAVLLVTLEDVNDNGPVLTVG--EARVAEN 1253

Query: 700  SPIGTTIGEIRAHDPDEGPN--AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757
             P GT +  +RA DPD  PN        + GG  ++ F L     S    L T  ++D E
Sbjct: 1254 QPPGTVVTTLRASDPDLPPNQGPFTFRLLGGGPAADYFGL-----SPAGLLTTAREIDRE 1308

Query: 758  S-PRKKYELVIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR 815
               R    +V+R +  PP+ +   V ILV D NDN    +  ++  ++Y   FP G  G 
Sbjct: 1309 QVSRFLLPVVVRDSGLPPMSSTGTVLILVADRNDNPSQPRPLEVFVHHYGGPFPGGVLGG 1368

Query: 816  VPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN- 874
            V   D D  D  +  + SG      L +   G+ +LS +          + V   DG + 
Sbjct: 1369 VRPLDPDEDDDFRCSLASGPAG---LFSVPAGTCSLSARARA-ADGTFDLRVLGDDGAHG 1424

Query: 875  EIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLS----PLLGFFIDGLAAIIPCPKEN 930
             + + +++S        L +SI +RL   +A  FL+    PLL      L+ +       
Sbjct: 1425 PVVSDVRVSFAAFGNATLDHSILLRLAAPSAGAFLAAHYLPLLQIAGSQLSGL----GGG 1480

Query: 931  IYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLA 990
            + ++ + +D +  G  L ++   R P   +   G  +   S   ++E V+  R +  R+ 
Sbjct: 1481 LQLYGLYEDEEGGGAFL-LAAVRRGPHRYLSPGGAAAFFES---VKESVF--RQSGLRIE 1534

Query: 991  TVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGF 1050
             V+  P     C   PC N   C   L  G       S  V+      +  F CQC  G+
Sbjct: 1535 EVEPDP-----CARGPCRNGGACARRLAVGPLFKSRESPPVILVANEVLQPFVCQCAPGY 1589

Query: 1051 TGVNCETILTKASCEVDGDGSICR 1074
             G  CET + +       +G  CR
Sbjct: 1590 AGGRCETDVDECLPAPCHNGGACR 1613



 Score =  305 bits (748), Expect = 1e-80
 Identities = 265/903 (29%), Positives = 406/903 (44%), Gaps = 92/903 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +NVLD NDHSP F  Q + ASV E A  G TV     +D+D G+NA   Y+I    AD+ 
Sbjct: 365  VNVLDENDHSPRFS-QLFSASVPENAPVGFTVTRATTSDEDEGQNAVSRYSI----ADSG 419

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             P                 F ID  +G +     LDRE VARY + V A D    VS   
Sbjct: 420  LP-----------------FAIDPSTGDITVSRPLDREDVARYRIRVSAHDSGWTVS--- 459

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
                 + V + D NDN P+F E +Y +   E   V     +A++ ATD D G N  + Y 
Sbjct: 460  ---TDVAVAVTDVNDNAPRFREPSYFLECPELPEVGSG--VARVAATDPDEGPNGQVFYL 514

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDY------EQVRSYRLVIRAQDGGSPSRSNTTQLL 244
            +   +    F +D+++G++   + L Y           +  V+   D GSP   + T + 
Sbjct: 515  L--KSPSEFFRVDAVTGEIFNKQPLRYLNGTGSVHANRHSFVVTCSDRGSPPLLSETTVT 572

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY-DADEGVNAELTYTMTDKDYTG 303
            +++ D ND+ PRF ++ +   V ++V +G  +++V A  D D G+N+ + Y +T ++   
Sbjct: 573  VHVVDGNDHPPRFLSAGYSTPVPKDVSVGTRVIQVAAADDGDFGLNSRVEYLLTGQEPAA 632

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
               L    D  +GWV  +  L  +    ++L VTA DGG PP SA AT            
Sbjct: 633  RFGL----DAETGWVSVAAPLTGDVDRTFRLSVTARDGGRPPLSAGATVRILVTEANAHT 688

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGG--------------- 406
              F   +  VE+ E    G  V  L A D+D  E+  L Y    G               
Sbjct: 689  PEFPRDRVRVEVPETLAVGAVVCVLAARDSDPAENGLLFYAFPPGTGVSYLAAEDEQEVS 748

Query: 407  -NTRGRFSITSQN---------GRGLITVAQPLDFKQERRYVLTVSATDSGGR---SDTA 453
              +R  + +T Q            G ++VA PL    +R + L+V+A D GGR   S  A
Sbjct: 749  IKSRVEYLLTGQEPAARFGLDAETGWVSVAAPLTGDVDRTFRLSVTARD-GGRPPLSAGA 807

Query: 454  MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513
             V+I +T+AN + P F        V E   +G  V V++A D+D   N  + Y++S+   
Sbjct: 808  TVRILVTEANAHTPEFPRDRVRVEVPETLAVGAVVCVLAARDADPAENGLLAYAVSA--- 864

Query: 514  NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
                 + +  F +N  TG +T    LD ET   + +TV+A DGG  + +    V + V+D
Sbjct: 865  ----GNGEGLFAVNASTGVLTLAGALDYETGRSHEVTVSATDGGWAARTGFCAVTVDVLD 920

Query: 574  VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633
            VNDN PVF    YT  + E+A  GT V  + ATDAD G N  + Y L   D +   F +D
Sbjct: 921  VNDNPPVFAGAEYTPEVAENAPSGTPVVTLRATDADSGPNAVVAYALHEADGD--LFAVD 978

Query: 634  PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693
            P +GV+ T   LD E+   H L   A +     + +   V +++  +N+  P F S    
Sbjct: 979  PNTGVVSTQGFLDYETRREHRLTVKAFNVPDEERCAFAAVTVRVTGVNEYIPRFVSAAYG 1038

Query: 694  FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753
            F +SE +P GT +G++ A D D GP+  V Y + G      F +E   G  +  +   +D
Sbjct: 1039 FEVSEAAPPGTPVGQVFAGDRDRGPDGEVSYLLFGESRRKGFRVERETG--QISVAGPLD 1096

Query: 754  LDYESPRKKYELVIRAASPPLWNDV-RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP 812
             + E       ++ + A P    DV  V + VT ++ N P +   +       +  P G 
Sbjct: 1097 REREG-TVALRVLAKNAGPIRGADVDEVAVNVTVLDANDPPVFGAETYRVRISEGVPPGT 1155

Query: 813  FGR-VPAYDAD---VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVS 868
                V A DAD      +  YR+      +   ++  TG +T++  L+     +  + V 
Sbjct: 1156 HVTFVGAADADSVPAWSRFSYRV-GPAGGDAFSVHPQTGQVTVTAPLDRETLPVYNLTVL 1214

Query: 869  VTD 871
              D
Sbjct: 1215 AVD 1217



 Score =  265 bits (649), Expect = 1e-68
 Identities = 241/818 (29%), Positives = 358/818 (43%), Gaps = 66/818 (8%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           FRID   GA+     L  E    ++V V+   + SP +D  S+T T+      D   +P+
Sbjct: 117 FRIDPTRGAITAAEPLAGEAEVTFSVHVRDGGR-SPQAD--STTVTVRFAAAGD---FPR 170

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209
              +  +    E   V  +PV   +  T +  G  S   Y +  GN    F  D L+G V
Sbjct: 171 VRAEGRSFLFPESQQV-GSPVTV-VTGTSSRAGPLS---YHVASGNFGGAFHADQLTGQV 225

Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269
           +  + LD+E ++ + + I A+D G P  S+  +L + ++DVNDNAP F    F   ++EN
Sbjct: 226 TTGRPLDFEAIQRFVVWIEARDAGFPPFSSYERLEVEVQDVNDNAPDFREDPFVAEIAEN 285

Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329
           +P    ++ V A D D G N +L Y +      GN +    I   +G + ++  LDRE+ 
Sbjct: 286 LP-PRRVLAVAAADRDSGPNGQLDYGIV----AGNEEGHFAIHRATGEIRSTRPLDRESV 340

Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389
            +Y+L V A+D GDPPRSATA               F    +   + E+ P G  V   T
Sbjct: 341 PRYRLTVRASDRGDPPRSATARVVVNVLDENDHSPRFSQ-LFSASVPENAPVGFTVTRAT 399

Query: 390 ATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR 449
            +D DE        +  ++   F+I    G   ITV++PLD +   RY + VSA DSG  
Sbjct: 400 TSDEDEGQNAVSRYSIADSGLPFAIDPSTGD--ITVSRPLDREDVARYRIRVSAHDSGWT 457

Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509
             T  V + +TD N+ AP F    Y     E   +G+ V  V+ATD D G N Q+ Y L 
Sbjct: 458 VSTD-VAVAVTDVNDNAPRFREPSYFLECPELPEVGSGVARVAATDPDEGPNGQVFYLLK 516

Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG------YLLTVTARDGGVPSLSD 563
           S           + F ++  TG I   + L     +G      +   VT  D G P L  
Sbjct: 517 SP---------SEFFRVDAVTGEIFNKQPLRYLNGTGSVHANRHSFVVTCSDRGSPPLLS 567

Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT-DADVGLNGRIHYELDP 622
            T V + VVD ND+ P F    Y+  + +D  VGT V QV A  D D GLN R+ Y L  
Sbjct: 568 ETTVTVHVVDGNDHPPRFLSAGYSTPVPKDVSVGTRVIQVAAADDGDFGLNSRVEYLLTG 627

Query: 623 KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND 682
           ++     F +D  +G +     L  +   T  L   A DGG PP S+   V I + + N 
Sbjct: 628 QE-PAARFGLDAETGWVSVAAPLTGDVDRTFRLSVTARDGGRPPLSAGATVRILVTEANA 686

Query: 683 SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG--------DDSNS 734
             P F  D +   + E   +G  +  + A D D   N ++ Y+   G        +D   
Sbjct: 687 HTPEFPRDRVRVEVPETLAVGAVVCVLAARDSDPAENGLLFYAFPPGTGVSYLAAEDEQE 746

Query: 735 FSLETRQG--SDKAELVTMVDLDYES------------PRKKYELVIRA---ASPPLWND 777
            S+++R        E      LD E+              + + L + A     PPL   
Sbjct: 747 VSIKSRVEYLLTGQEPAARFGLDAETGWVSVAAPLTGDVDRTFRLSVTARDGGRPPLSAG 806

Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRV-PAYDADVTDK--LQYRILSG 834
             V ILVT+ N + P     ++      +   VG    V  A DAD  +   L Y + +G
Sbjct: 807 ATVRILVTEANAHTPEFPRDRVRV-EVPETLAVGAVVCVLAARDADPAENGLLAYAVSAG 865

Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
           N   L  +N +TG +TL+  L+    +   + VS TDG
Sbjct: 866 NGEGLFAVNASTGVLTLAGALDYETGRSHEVTVSATDG 903



 Score =  229 bits (559), Expect = 1e-57
 Identities = 191/633 (30%), Positives = 294/633 (46%), Gaps = 49/633 (7%)

Query: 174 IKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233
           +  TD D G NS + +++ G +++ +F ID   G ++  + L  E   ++ + +R  DGG
Sbjct: 92  VTVTDPDTGPNSELHFSLSGSHSE-RFRIDPTRGAITAAEPLAGEAEVTFSVHVR--DGG 148

Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293
              ++++T + +      D  PR           E+  +G  +  V    +  G    L+
Sbjct: 149 RSPQADSTTVTVRFAAAGD-FPRVRAEGRSFLFPESQQVGSPVTVVTGTSSRAG---PLS 204

Query: 294 YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353
           Y +     +GN       D  +G V T   LD E   ++ + + A D G PP S+     
Sbjct: 205 YHVA----SGNFGGAFHADQLTGQVTTGRPLDFEAIQRFVVWIEARDAGFPPFSSYERLE 260

Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGR 411
                       F    +  E+AE+ PP   V+ + A D D   + +L Y I  GN  G 
Sbjct: 261 VEVQDVNDNAPDFREDPFVAEIAENLPP-RRVLAVAAADRDSGPNGQLDYGIVAGNEEGH 319

Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVF 469
           F+I      G I   +PLD +   RY LTV A+D G   RS TA V +N+ D N+++P F
Sbjct: 320 FAI--HRATGEIRSTRPLDRESVPRYRLTVRASDRGDPPRSATARVVVNVLDENDHSPRF 377

Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
               ++ASV E+AP+G TV   + +D D G NA         +S  ++A     F I+P 
Sbjct: 378 SQL-FSASVPENAPVGFTVTRATTSDEDEGQNA---------VSRYSIADSGLPFAIDPS 427

Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589
           TG IT ++ LDRE ++ Y + V+A D G    + +TDV ++V DVNDN P F++  Y   
Sbjct: 428 TGDITVSRPLDREDVARYRIRVSAHDSG---WTVSTDVAVAVTDVNDNAPRFREPSYFLE 484

Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL---- 645
             E   VG+ V++V ATD D G NG++ Y L  K   E  F +D  +G I   + L    
Sbjct: 485 CPELPEVGSGVARVAATDPDEGPNGQVFYLL--KSPSE-FFRVDAVTGEIFNKQPLRYLN 541

Query: 646 DRESVAT--HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703
              SV    H       D G+PP  S   V + + D ND PP F S   +  + ++  +G
Sbjct: 542 GTGSVHANRHSFVVTCSDRGSPPLLSETTVTVHVVDGNDHPPRFLSAGYSTPVPKDVSVG 601

Query: 704 TTIGEI-RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762
           T + ++  A D D G N+ V Y + G + +  F L+   G          D+D     + 
Sbjct: 602 TRVIQVAAADDGDFGLNSRVEYLLTGQEPAARFGLDAETGWVSVAAPLTGDVD-----RT 656

Query: 763 YELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792
           + L + A     PPL     V ILVT+ N + P
Sbjct: 657 FRLSVTARDGGRPPLSAGATVRILVTEANAHTP 689



 Score =  213 bits (520), Expect = 6e-53
 Identities = 170/611 (27%), Positives = 279/611 (45%), Gaps = 35/611 (5%)

Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329
           +P G  +  V   D D G N+EL ++++     G+      IDP  G +  +  L  E +
Sbjct: 83  LPAGLFVFAVTVTDPDTGPNSELHFSLS-----GSHSERFRIDPTRGAITAAEPLAGEAE 137

Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389
             + + V   DGG  P++ + T                 G+  +   E +  G+PV  +T
Sbjct: 138 VTFSVHVR--DGGRSPQADSTTVTVRFAAAGDFPRVRAEGRSFL-FPESQQVGSPVTVVT 194

Query: 390 ATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR 449
            T +     L Y +  GN  G F      G+  +T  +PLDF+  +R+V+ + A D+G  
Sbjct: 195 GTSS-RAGPLSYHVASGNFGGAFHADQLTGQ--VTTGRPLDFEAIQRFVVWIEARDAGFP 251

Query: 450 --SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507
             S    +++ + D N+ AP F   P+ A + E+ P    VL V+A D D G N Q+ Y 
Sbjct: 252 PFSSYERLEVEVQDVNDNAPDFREDPFVAEIAENLP-PRRVLAVAAADRDSGPNGQLDYG 310

Query: 508 LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567
           + +   NE     +  F I+  TG I + + LDRE++  Y LTV A D G P  S T  V
Sbjct: 311 IVA--GNE-----EGHFAIHRATGEIRSTRPLDRESVPRYRLTVRASDRGDPPRSATARV 363

Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627
            ++V+D ND+ P F Q L++A++ E+A VG +V++   +D D G N    Y +       
Sbjct: 364 VVNVLDENDHSPRFSQ-LFSASVPENAPVGFTVTRATTSDEDEGQNAVSRYSIADSGLP- 421

Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687
             F IDP++G I  ++ LDRE VA + ++  A D G    +    V + + D+ND+ P F
Sbjct: 422 --FAIDPSTGDITVSRPLDREDVARYRIRVSAHDSGWTVSTD---VAVAVTDVNDNAPRF 476

Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747
                     E   +G+ +  + A DPDEGPN  V Y +K   +       T +  +K  
Sbjct: 477 REPSYFLECPELPEVGSGVARVAATDPDEGPNGQVFYLLKSPSEFFRVDAVTGEIFNKQP 536

Query: 748 LVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY 804
           L   ++        ++  V+  +   SPPL ++  V + V D ND+ P            
Sbjct: 537 L-RYLNGTGSVHANRHSFVVTCSDRGSPPLLSETTVTVHVVDGNDHPPRFLSAGYSTPVP 595

Query: 805 KDCFPVGPFGRVPAY---DADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPK 861
           KD        +V A    D  +  +++Y +     A    L+  TG ++++  L  +V +
Sbjct: 596 KDVSVGTRVIQVAAADDGDFGLNSRVEYLLTGQEPAARFGLDAETGWVSVAAPLTGDVDR 655

Query: 862 LATMEVSVTDG 872
              + V+  DG
Sbjct: 656 TFRLSVTARDG 666



 Score = 44.8 bits (101), Expect = 0.035
 Identities = 17/39 (43%), Positives = 19/39 (48%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C      C  APC+NG  C DL   + C C EG  GK C
Sbjct: 1594 CETDVDECLPAPCHNGGACRDLVGAFACSCPEGFGGKAC 1632


>UniRef50_Q60YX0 Cluster: Putative uncharacterized protein CBG18050;
            n=1; Caenorhabditis briggsae|Rep: Putative
            uncharacterized protein CBG18050 - Caenorhabditis
            briggsae
          Length = 4339

 Score =  310 bits (762), Expect = 3e-82
 Identities = 346/1393 (24%), Positives = 583/1393 (41%), Gaps = 135/1393 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +++LD ND++P F     + ++ E A+ GT+V    A D+D   +  + ++  LV  D  
Sbjct: 2702 LDILDVNDNAPAFHGDYDKLTISEDATVGTSVTIFSAMDRDDSPSGRIRFS--LVNKD-- 2757

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             P                 F ++G SG L   A LDRE    Y ++ +ATD+    +D  
Sbjct: 2758 -PH----------------FEMNGDSGWLTVAAPLDRETQDLYQLIARATDEGGFNTDL- 2799

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
              + TI VN  D ND+ P+F +  +    D D+ +  N +I      D D+  N+     
Sbjct: 2800 --SFTISVN--DVNDSPPKFEKDEF----DVDLLLPSNALILHFDIKDEDLAPNNHSLLF 2851

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I  GN +  F IDS   ++ L +    E  + Y L I A DG   +++     L +  DV
Sbjct: 2852 ISEGNEEGVFWIDS-ENNLLLKRPEIVENKKEYSLKIIAFDGVFEAKTLVKIHLKSKEDV 2910

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
                P    ++     S+   + +            G ++ L    T K      +    
Sbjct: 2911 KTRCPDVEKTVILPESSKKGTVVF------------GESSLLGPNTTFKLIEEGAENAFV 2958

Query: 311  IDPRSGWVYTS--GQLDRETQAKYQLLVTATDGGDP--PRSATATXXXXXXXXXXXXXXF 366
            ++ R+G +     GQ+D E   +++L+     G D       T                 
Sbjct: 2959 MNFRNGIIKVKEVGQIDYEKTQEFELIRLTIQGKDELCKERITVKIENLNDNPPKIKEKS 3018

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
            +    E  L   +     +  + A DAD D+ +H+ +     +  F I   +G  ++TV 
Sbjct: 3019 VYVSIEENLPTSQDSRQYLTRIAAEDADSDD-IHFRLLDDFNK-TFEIDEFSG--VVTVL 3074

Query: 427  QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
            +PLD +    + LT  A+D G   D A++ + + D N+ AP FE + Y+  V E   +G 
Sbjct: 3075 KPLDSESVSSFNLTAIASD-GNFEDKAIIVVTVIDKNDNAPTFEKSTYSMKVMESEAVGY 3133

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
             +  + A   D   N  I YSL +   N+ V+       +N Q G +T  + LD ET+S 
Sbjct: 3134 ELARLQAFGGDT--NETIEYSLKASDHNKFVS-------LNAQNGVLTLAQPLDFETIST 3184

Query: 547  YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
              LTV A+D G+P L     VEISV+D NDN P F+++ YT  + E++ VG  V  V A 
Sbjct: 3185 LRLTVIAKDSGIPPLESVAQVEISVMDENDNAPKFEKEKYTGKVKENSKVGEKVLTVKAV 3244

Query: 607  DADVGLNGRIHYELD------PKDREEGSFVIDP----ASGVIRTNKALDRESVATHDLK 656
            DAD    G + YEL+        D    + V  P    A+G +  N+ +D E    ++LK
Sbjct: 3245 DADSEHFGAVSYELELIADKASDDSLPTTSVTPPFSINANGDVLINQPIDYEKTKKYNLK 3304

Query: 657  AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
             +A DGG PP  S  ++ I + D ND+ PVF+   +T  + E   IG  + +    D D 
Sbjct: 3305 LIAKDGGRPPLVSEALLDIHVGDENDNAPVFDDCNMTAVVQEGESIGHKVLKFSISDLD- 3363

Query: 717  GPNAVVHYSIK-GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW 775
            GP     ++++  GD + SF +     +DK EL+T   L++ +  K    VI   +    
Sbjct: 3364 GPTNGAPFTVEIQGDGAKSFKV-----NDKLELLTAKKLEHRNKDKYLLTVIAKDTKGKS 3418

Query: 776  NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK---LQYRIL 832
             D  + + +   + +AP MK  +I  N  ++  P G  GR+ A+D D  D+   L++ I+
Sbjct: 3419 TDCPLTVFIRQASRHAPTMKPMKIQVNTLQNELPEGVIGRLKAFDEDEEDQNGLLRFGIV 3478

Query: 833  SGNNAN-LILLNET--TGSMTLSPQLNT-----NVPK-LATMEVSVTDGVNEIKAMMQLS 883
             G+  +  + + E+  T    + P         ++P+ L T  V+V+DG     + +++ 
Sbjct: 3479 EGSTQSPRVQMQESRPTHLFRIDPTTGDIWSDHSIPQGLHTFNVTVSDGKFTTVSYVEVQ 3538

Query: 884  VRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKEN-IYIFSVQDDTDV 942
            V  I  +++ +++++R+  MT E F+   +  F   ++  +    EN I + SVQ     
Sbjct: 3539 VNSIDNDVIDHAVSIRIRSMTVEDFMKNHVKEFRRIISHHLNLNDENSIQLISVQQ-VPS 3597

Query: 943  TGNILNVSFSARRPDAEVGVA-----GDPSPHYSPTHLRERVYLHRTTLARLATVQVLPF 997
            T +  N   S R P  +V V      G    +  P H+  R+      +   +       
Sbjct: 3598 TDSARNRR-SKRGPSEDVEVLMTAQRGHGRGYLKPDHVYSRLKNDFQNMNDQSQRMRYQL 3656

Query: 998  DDNICVHEPCLNFEECLTVLKFGNASGF-VNSDSVLFRPIYPVTSFTCQCPEGFTGVNCE 1056
               +C    CL   EC  V++  + S   V+++   F   +      C CP+GF G  CE
Sbjct: 3657 ITEMCTTGVCLR-GECREVIELIDDSWTKVSTEEFSFVSPFHSRFAQCLCPDGFGGKRCE 3715

Query: 1057 ---TILTKASCEVDGD--GSICRSGSQCVARREGGILCQGCSIDAAYTTAVCELRARSFP 1111
                  +K+ CE       S+  S  +CV     G+    C + +      C L      
Sbjct: 3716 IETNQCSKSPCEQWQMCIPSVFNSTFECVCPL--GMEGDRCLVPSCKNDGKC-LEEAELS 3772

Query: 1112 VSS---FLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRGG 1168
            V     F      +   R+ L+++  T + +G+++++     RHD+  L LV+  A    
Sbjct: 3773 VGGDGYFEISLSNEIESRMELEIELKTTSPNGIIMWS---RGRHDYHMLRLVNGSA---- 3825

Query: 1169 GPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMIL--DDCDKVLSLAGAAD 1226
                ++ +  G G   +T +  + DG WH + I    R   M +  D  ++  S  G+  
Sbjct: 3826 ----QYHWDAGTGTGIVTSKTLIVDGQWHRITISRRQRRTRMTVDDDGLEEAFSPVGSTV 3881

Query: 1227 FGLKYACANFT--RKVLPARCEIPTETCHRFLDLTG--------PLQIGGL-PNIPSSFQ 1275
              L           KV   +       C R + + G         +++ G+ P   +   
Sbjct: 3882 VNLHRYSQKLVLGAKVENGQLTDGISGCFRTISIDGIKVLKTRQGMKLFGVQPGCSALTS 3941

Query: 1276 VKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTY 1335
                D         + H             +   C      CSS PC  G +C   ++ Y
Sbjct: 3942 SPCNDLPCKHGGTCVSHGKSQFVCQCTSRYSGDTCEIDLEPCSSTPCPTGIQCIPFYNDY 4001

Query: 1336 ICDCKEGHTGKDC 1348
            +C C  G TGK C
Sbjct: 4002 LCKCPNGFTGKHC 4014



 Score =  257 bits (629), Expect = 4e-66
 Identities = 241/909 (26%), Positives = 413/909 (45%), Gaps = 70/909 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + ++D N+HSPV+  +    +       G  +L + ATDQD G N  V Y I       +
Sbjct: 475  VEIVDSNNHSPVWSAKWMRQAPIPLGKPGDVLLKVDATDQDEGDNGRVVYKINSEIPFEI 534

Query: 71   NPEDAXXXXXXXXXXVQD----VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
            N                +    V+ ID   G  L+R S     +  Y    K   +  PV
Sbjct: 535  NANTGEITLIEVPTKSNNWMVTVWAID--LGLPLSRMSA--LNLMFYKNGTKVPAKPKPV 590

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
              + S           +N + P FS     V V ED  +    V+AK++++D D G N  
Sbjct: 591  IIQES-----------ENKHSPVFSSFPEVVEVTEDAPI--GTVVAKLQSSDEDAGYNGL 637

Query: 187  IRYAI--IGGNTQMQFSIDSLSGDVSLVKTL-----DYEQVRSYRLVIRAQDGGSPSRSN 239
            IRY I  I G++    S+D  SG++++   L     + ++V   ++ + A D G+P +S 
Sbjct: 638  IRYVIQDISGSSHEILSVDEQSGEITVASDLTLLMKEKQKVVEIQVKVSAVDAGTPVKSA 697

Query: 240  TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
            T  + + I+DVN+++P F    +  ++SE+   G  I +  A D D G N ++ +++ + 
Sbjct: 698  TRTMKLRIKDVNNHSPHFDEPSYYLAISESEKPGKDIFKATANDFDGGNNGKIKFSLGNN 757

Query: 300  DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
                +V   I+I+P++G +     LDRE Q  +   + A+D GDP R             
Sbjct: 758  GAESSV---ISIEPKTGIIKLLNPLDREEQDVHYFSIIASDDGDPARITVTNLTITVDDV 814

Query: 360  XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG 419
                   +    +  + ED P G  V  L A D D       +      +  F +   +G
Sbjct: 815  NDNAPRCVSQVAKARIPEDLPHGAFVACLAAFDEDVGLNSKLKFLLNAEKVPFRVDHHSG 874

Query: 420  RGLITVAQ-PLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDA--NNYAPVFENAPY 474
              L      PLD+++   + L++   D G    S T  +++ + D    + A  F++   
Sbjct: 875  CLLGNSPDVPLDYQKTPNFNLSIEVADHGEPMLSTTCFLEVELVDVPHKHLAIEFDDVAK 934

Query: 475  TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
             ASV+E++ IGT V++V A   ++G   ++    +  +    +  +   +    Q G + 
Sbjct: 935  EASVYENSEIGTEVIMVEA--KEMGDEQKVK---AENLEYRIIGGNGWPYFSIDQKGTVR 989

Query: 535  TNKLLDRETMSGYLLTVTARDGGVPSLSD-----TTDVEISVVDVNDNEPVFKQQLYTAN 589
            T  +LDRE  S Y +TV ARD       D        V I ++D ND+ PV K  +Y A+
Sbjct: 990  TTHILDREKRSAYWITVEARDAKTDFYKDPRRRAVLHVFIRILDRNDHRPVAKSAMYIAS 1049

Query: 590  IMEDALVGTSVSQVGATDA-DVGLNGR--IHYELDPKDREEGSFVIDPASGVIRTN--KA 644
            ++E++     + +V ATDA D+  +G   + ++++  D  +  F ID ASG I T+  + 
Sbjct: 1050 VLENSPANVVIVKVEATDADDIDNDGAAPLTFKIERGD-PQSFFRIDLASGYITTSGIRR 1108

Query: 645  LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
            LDRE  A H+L     DGG P   S V+V +K+ D ND+ P F +  +  Y   +  IG 
Sbjct: 1109 LDREKQAEHELWISICDGGEPQLCSNVVVIVKVLDENDNAPTF-TQAMHHYNVRSKHIG- 1166

Query: 705  TIGEIRAHDPDEGPNAVVHYSIKGGD-----DSNSFSLETRQ-GSDKAELVTMVDLDYES 758
             +  I A D DEG N+ + Y++  GD     D N   + +    SD++  +T+   D+ S
Sbjct: 1167 KLCRIFAVDIDEGENSHLSYNVTEGDPRFSIDENGNIMTSEAIHSDESYALTLQATDHGS 1226

Query: 759  PRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF-NNYKDCFPVG-PFGRV 816
            P +++     AA+  +   V          ++ PV+   +  +     D   VG   G++
Sbjct: 1227 PSQQF-----AATRVVLTAVGSSQKTKKSKNSPPVISGKKSDYVIPISDADQVGLTVGKL 1281

Query: 817  PAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG--VN 874
             A DAD  D L + I SG++ ++  + + TG + L+ ++         + +SVTDG  V+
Sbjct: 1282 EATDAD-GDDLWWNIFSGDSDSVFDVRQDTGQLLLAKKVELLKRGELRLNISVTDGQDVD 1340

Query: 875  EIKAMMQLS 883
                ++Q+S
Sbjct: 1341 HTTVIIQVS 1349



 Score =  225 bits (551), Expect = 1e-56
 Identities = 208/795 (26%), Positives = 364/795 (45%), Gaps = 85/795 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            ++V+D ND  P F +  Y  S+ E A  G TVL + ATD+D  +N  +EY++       L
Sbjct: 2495 LSVIDINDKPPFFVLPFYSTSIPETAKEGDTVLMVSATDED--ENDTIEYSL-------L 2545

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +  ++              F +  R G +     L+ +     ++ +KATD A+P     
Sbjct: 2546 DGGES------------QFFSVHPRQGTITVSKKLEHKAGVTLSLTIKATDSANPPH--- 2590

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             +T T+ +N+  ++   P+FS   Y   V ED  + D  V+  ++  + ++     +R+ 
Sbjct: 2591 HATTTVEINVASESVRVPRFSNSHYLFFVPEDADIGD--VVGSVQQMETEI---DEVRFT 2645

Query: 191  IIGG----NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            I+ G    ++ + FS++  +G + +  +LD E+ + +++ IRA   G      T  L  +
Sbjct: 2646 IVPGSEVSDSLLPFSVERSTGKIIVKSSLDRERRKQWKMTIRADAAGGVHAITTVTL--D 2703

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            I DVNDNAP F+    + ++SE+  +G S+    A D D+  +  + +++ +K      D
Sbjct: 2704 ILDVNDNAPAFHGDYDKLTISEDATVGTSVTIFSAMDRDDSPSGRIRFSLVNK------D 2757

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
                ++  SGW+  +  LDRETQ  YQL+  ATD G    +   +              F
Sbjct: 2758 PHFEMNGDSGWLTVAAPLDRETQDLYQLIARATDEGG--FNTDLSFTISVNDVNDSPPKF 2815

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLIT 424
               +++V+L    P    ++     D D   +N     I+ GN  G F I S+N    + 
Sbjct: 2816 EKDEFDVDLL--LPSNALILHFDIKDEDLAPNNHSLLFISEGNEEGVFWIDSENN---LL 2870

Query: 425  VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
            + +P   + ++ Y L + A D    + T +V+I++    +      +   T  + E +  
Sbjct: 2871 LKRPEIVENKKEYSLKIIAFDGVFEAKT-LVKIHLKSKEDVKTRCPDVEKTVILPESSKK 2929

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL--LDRE 542
            GT   VV    S +G N   T+ L  E +  A       FV+N + G I   ++  +D E
Sbjct: 2930 GT---VVFGESSLLGPNT--TFKLIEEGAENA-------FVMNFRNGIIKVKEVGQIDYE 2977

Query: 543  -TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS-- 599
             T    L+ +T +  G   L     + + + ++NDN P  K++    +I E+        
Sbjct: 2978 KTQEFELIRLTIQ--GKDELCKER-ITVKIENLNDNPPKIKEKSVYVSIEENLPTSQDSR 3034

Query: 600  --VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
              ++++ A DAD   +  IH+ L   D    +F ID  SGV+   K LD ESV++ +L A
Sbjct: 3035 QYLTRIAAEDAD---SDDIHFRL--LDDFNKTFEIDEFSGVVTVLKPLDSESVSSFNLTA 3089

Query: 658  VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
            +A DG    ++   I+ + + D ND+ P FE    +  + E+  +G  +  ++A   D  
Sbjct: 3090 IASDGNFEDKA---IIVVTVIDKNDNAPTFEKSTYSMKVMESEAVGYELARLQAFGGD-- 3144

Query: 718  PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND 777
             N  + YS+K  D +   SL  + G     L   +D +  S  +   +   +  PPL + 
Sbjct: 3145 TNETIEYSLKASDHNKFVSLNAQNG--VLTLAQPLDFETISTLRLTVIAKDSGIPPLESV 3202

Query: 778  VRVEILVTDVNDNAP 792
             +VEI V D NDNAP
Sbjct: 3203 AQVEISVMDENDNAP 3217



 Score =  193 bits (470), Expect = 7e-47
 Identities = 212/893 (23%), Positives = 379/893 (42%), Gaps = 78/893 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + + D ND+ PVF   + +A V + A SG  +  + ATD D    + ++   + +    +
Sbjct: 2273 VMIEDVNDNMPVFIRPEVKAEVSDAAISGQFITIMSATDMDT--TSSLDDPNQKLLYKIV 2330

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            + ++           V    RI+      LT  S D +KV    V V  TD         
Sbjct: 2331 DGDETLFNISPSTGEVSLARRIEQED---LTSESEDPKKV----VNVSVTD------GMF 2377

Query: 131  SSTATIHVNIIDDNDNYP--QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            ++ A + V I+      P  +F +  Y  +  E+  V  + ++     T A  G    +R
Sbjct: 2378 TAYAKLVVGILRSGKMQPPPKFEQSHYVATALENTIVNKSALL-----TVAVKGGIPPLR 2432

Query: 189  YAI--------IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240
            Y++                 +ID  +G + + + L+Y   + Y++ +  +D     R   
Sbjct: 2433 YSLGPAAYSNSSSSKDSWPVAIDKKTGRIHVSRVLNYHNDKLYQIPLVVED--VTRRRAF 2490

Query: 241  TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
            + L +++ D+ND  P F    +  S+ E    G +++ V A D DE  N  + Y++ D  
Sbjct: 2491 STLTLSVIDINDKPPFFVLPFYSTSIPETAKEGDTVLMVSATDEDE--NDTIEYSLLD-- 2546

Query: 301  YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
              G      ++ PR G +  S +L+ +      L + ATD  +PP  AT T         
Sbjct: 2547 --GGESQFFSVHPRQGTITVSKKLEHKAGVTLSLTIKATDSANPPHHATTTVEINVASES 2604

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGN--TRGRFSITSQN 418
                 F    Y   + ED   G  V ++   + + D  + + I  G+  +      + + 
Sbjct: 2605 VRVPRFSNSHYLFFVPEDADIGDVVGSVQQMETEIDE-VRFTIVPGSEVSDSLLPFSVER 2663

Query: 419  GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASV 478
              G I V   LD ++ +++ +T+ A  +GG      V ++I D N+ AP F       ++
Sbjct: 2664 STGKIIVKSSLDRERRKQWKMTIRADAAGGVHAITTVTLDILDVNDNAPAFHGDYDKLTI 2723

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             EDA +GT+V + SA D D   + +I +SL          + D  F +N  +G +T    
Sbjct: 2724 SEDATVGTSVTIFSAMDRDDSPSGRIRFSL---------VNKDPHFEMNGDSGWLTVAAP 2774

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            LDRET   Y L   A D G    +      ISV DVND+ P F++  +  +++  +    
Sbjct: 2775 LDRETQDLYQLIARATDEG--GFNTDLSFTISVNDVNDSPPKFEKDEFDVDLLLPS--NA 2830

Query: 599  SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
             +      D D+  N      +  +  EEG F ID  + ++     +  E+   + LK +
Sbjct: 2831 LILHFDIKDEDLAPNNHSLLFIS-EGNEEGVFWIDSENNLLLKRPEI-VENKKEYSLKII 2888

Query: 659  AIDGGTPPQSSTVIVHIKI-EDINDSPPVFESDCLTFYISENSPIGTTI-GEIRAHDPDE 716
            A D G     + V +H+K  ED+    P  E    T  + E+S  GT + GE        
Sbjct: 2889 AFD-GVFEAKTLVKIHLKSKEDVKTRCPDVEK---TVILPESSKKGTVVFGESSL----L 2940

Query: 717  GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN 776
            GPN       +G +  N+F +  R G  K + V  +D +     +   L I+     L  
Sbjct: 2941 GPNTTFKLIEEGAE--NAFVMNFRNGIIKVKEVGQIDYEKTQEFELIRLTIQ-GKDELCK 2997

Query: 777  DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-----FGRVPAYDADVTDKLQYRI 831
            + R+ + + ++NDN P +K+ + ++ + ++  P          R+ A DAD +D + +R+
Sbjct: 2998 E-RITVKIENLNDNPPKIKE-KSVYVSIEENLPTSQDSRQYLTRIAAEDAD-SDDIHFRL 3054

Query: 832  LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884
            L   N     ++E +G +T+   L++       +    +DG  E KA++ ++V
Sbjct: 3055 LDDFN-KTFEIDEFSGVVTVLKPLDSESVSSFNLTAIASDGNFEDKAIIVVTV 3106



 Score =  192 bits (468), Expect = 1e-46
 Identities = 193/769 (25%), Positives = 326/769 (42%), Gaps = 77/769 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND++P    Q  +A + E    G  V  L A D+D+G N+++++         L
Sbjct: 809  ITVDDVNDNAPRCVSQVAKARIPEDLPHGAFVACLAAFDEDVGLNSKLKFL--------L 860

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS---LDREKVARYTVLVKATDQASPVS 127
            N E                FR+D  SG LL  +    LD +K   + + ++  D   P+ 
Sbjct: 861  NAEKVP-------------FRVDHHSGCLLGNSPDVPLDYQKTPNFNLSIEVADHGEPM- 906

Query: 128  DRLSSTATIHVNIIDDNDNYP--QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
              LS+T  + V ++D    +   +F +     SV E+  +    ++ + K    +    +
Sbjct: 907  --LSTTCFLEVELVDVPHKHLAIEFDDVAKEASVYENSEIGTEVIMVEAKEMGDEQKVKA 964

Query: 186  A-IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS-----PSRSN 239
              + Y IIGGN    FSID   G V     LD E+  +Y + + A+D  +     P R  
Sbjct: 965  ENLEYRIIGGNGWPYFSIDQ-KGTVRTTHILDREKRSAYWITVEARDAKTDFYKDPRRRA 1023

Query: 240  TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
               + I I D ND+ P   ++++  SV EN P    IV+V+A DAD+ ++ +    +T K
Sbjct: 1024 VLHVFIRILDRNDHRPVAKSAMYIASVLENSPANVVIVKVEATDADD-IDNDGAAPLTFK 1082

Query: 300  DYTGNVDLPITIDPRSGWVYTSG--QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357
               G+      ID  SG++ TSG  +LDRE QA+++L ++  DGG+P   +         
Sbjct: 1083 IERGDPQSFFRIDLASGYITTSGIRRLDREKQAEHELWISICDGGEPQLCSNVVVIVKVL 1142

Query: 358  XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ 417
                    F    +   +          +     D  E++ L Y +T G+ R  FSI  +
Sbjct: 1143 DENDNAPTFTQAMHHYNVRSKHIGKLCRIFAVDIDEGENSHLSYNVTEGDPR--FSI-DE 1199

Query: 418  NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT-AMVQINIT---------DANNYAP 467
            NG  + + A       +  Y LT+ ATD G  S   A  ++ +T          + N  P
Sbjct: 1200 NGNIMTSEA----IHSDESYALTLQATDHGSPSQQFAATRVVLTAVGSSQKTKKSKNSPP 1255

Query: 468  VF--ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525
            V   + + Y   + +   +G TV  + ATD+D      + +++ S  S       D  F 
Sbjct: 1256 VISGKKSDYVIPISDADQVGLTVGKLEATDAD---GDDLWWNIFSGDS-------DSVFD 1305

Query: 526  INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585
            +   TG +   K ++        L ++  DG      D T V I V       P F    
Sbjct: 1306 VRQDTGQLLLAKKVELLKRGELRLNISVTDG---QDVDHTTVIIQVSRQISQRPAFSANR 1362

Query: 586  YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD-REEGSFVIDPASGVIRTNKA 644
            Y   + E   VGT +  + AT  ++G    ++      D   E    ++P+SG +   + 
Sbjct: 1363 YDTLVSERVAVGTQIHTLKATGENLGTKPLVYSLFSIDDIAMEDKIRVEPSSGNVIVMEP 1422

Query: 645  LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
            LD E VA+     V +        S +I  +++ D ND+ P F       ++ EN  +  
Sbjct: 1423 LDYE-VASQIRAVVQVQQANMKSFSKLI--LEVTDENDNAPYFVEHTAWAFVDENDSVDD 1479

Query: 705  TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753
             +  + A D D+  N ++ YSI  G++ + F +++  G  +  L  ++D
Sbjct: 1480 VLATVTAFDRDQDDNGIITYSIVSGNEESLFKIDSHSG--EVRLARLID 1526



 Score =  173 bits (420), Expect = 8e-41
 Identities = 211/910 (23%), Positives = 378/910 (41%), Gaps = 88/910 (9%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATD-QDIGKNAEVEYTIELV 65
            +H  I +LD NDH PV +   Y ASV E + +   ++ ++ATD  DI  +     T ++ 
Sbjct: 1025 LHVFIRILDRNDHRPVAKSAMYIASVLENSPANVVIVKVEATDADDIDNDGAAPLTFKIE 1084

Query: 66   TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRA--SLDREKVARYTVLVKATDQA 123
              D                  Q  FRID  SG + T     LDREK A + + +   D  
Sbjct: 1085 RGDP-----------------QSFFRIDLASGYITTSGIRRLDREKQAEHELWISICDGG 1127

Query: 124  SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183
             P   +L S   + V ++D+NDN P F++  +  +V           + +I A D D G 
Sbjct: 1128 EP---QLCSNVVVIVKVLDENDNAPTFTQAMHHYNVRSK----HIGKLCRIFAVDIDEGE 1180

Query: 184  NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS-NTTQ 242
            NS + Y +  G+ +  FSID  +G++   + +  ++  SY L ++A D GSPS+    T+
Sbjct: 1181 NSHLSYNVTEGDPR--FSIDE-NGNIMTSEAIHSDE--SYALTLQATDHGSPSQQFAATR 1235

Query: 243  LLINI------RDVNDNAPRFYT---SLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293
            +++           + N+P   +   S +   +S+   +G ++ +++A DAD     +L 
Sbjct: 1236 VVLTAVGSSQKTKKSKNSPPVISGKKSDYVIPISDADQVGLTVGKLEATDAD---GDDLW 1292

Query: 294  YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353
            + +    ++G+ D    +   +G +  + +++   + + +L ++ TDG D   +   T  
Sbjct: 1293 WNI----FSGDSDSVFDVRQDTGQLLLAKKVELLKRGELRLNISVTDGQDVDHT---TVI 1345

Query: 354  XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR-LHYEITG-GNTRGR 411
                        F   +Y+  ++E    GT + TL AT  +   + L Y +    +    
Sbjct: 1346 IQVSRQISQRPAFSANRYDTLVSERVAVGTQIHTLKATGENLGTKPLVYSLFSIDDIAME 1405

Query: 412  FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN 471
              I  +   G + V +PLD++   +    V    +  +S + ++ + +TD N+ AP F  
Sbjct: 1406 DKIRVEPSSGNVIVMEPLDYEVASQIRAVVQVQQANMKSFSKLI-LEVTDENDNAPYFVE 1464

Query: 472  APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
                A V E+  +   +  V+A D D   N  ITYS+ S   NE     +  F I+  +G
Sbjct: 1465 HTAWAFVDENDSVDDVLATVTAFDRDQDDNGIITYSIVS--GNE-----ESLFKIDSHSG 1517

Query: 532  AITTNKLLDRETMSGY-LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590
             +   +L+D E      +L + A D    SL D   + I    +      F +++Y  ++
Sbjct: 1518 EVRLARLIDPEMQHVVSILRIRASDSATISLKDELTLHIKSSKLTSENAKFDRKVYQTSL 1577

Query: 591  MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES- 649
             +    GT V  +         +G I ++L+P       F +   SG +   K + +E  
Sbjct: 1578 HDSTRPGTPVLVLNVLH-----HGAITFKLEPNCT---FFDVHTLSGAVHLAKWITKEKQ 1629

Query: 650  VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
            + T +  A  ++G    Q  T  +  KI   N   PVF        + EN   G+++   
Sbjct: 1630 LKTLECTAYVVNGDG--QQDTAKIVAKIIRTNQHSPVFRKQVYRGTVRENMEPGSSVLSN 1687

Query: 710  R-------AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762
            R       A D D G N +V Y +    D   F+++   G+ +       D +       
Sbjct: 1688 RHLPLVLLASDEDSGSNGLVGYRMLSKADEEMFTVDQYSGAVRTN--KAFDFEKIKEHSF 1745

Query: 763  YELVIRAASPPLWN--DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD 820
            Y        PP  +     V + ++D ND  P      +              G   + D
Sbjct: 1746 YVQAFDMGQPPRQSLMPALVVVTISDENDETPKFASQSLDVIMLLPTASQAVVGGQMSDD 1805

Query: 821  ADVTDKLQYRILSGNNANLILLNETTGSMTLSP-QLNTNVPKLATMEVSVTDGVNEIKAM 879
            AD    L+Y I   ++++   ++  TG +++   +  TN  K   +EV VTDG       
Sbjct: 1806 ADSIGTLRYYI--KDSSSPFSVDSKTGIVSVKDFKAFTNEKKHYNVEVFVTDGNQSTSYT 1863

Query: 880  MQLSVRLITE 889
            M+++     E
Sbjct: 1864 MKVTTTSTAE 1873



 Score =  171 bits (415), Expect = 3e-40
 Identities = 219/877 (24%), Positives = 379/877 (43%), Gaps = 90/877 (10%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ + D N+HSP F+   Y  ++ E    G  +    A D D G N ++++++    A++
Sbjct: 702  KLRIKDVNNHSPHFDEPSYYLAISESEKPGKDIFKATANDFDGGNNGKIKFSLGNNGAES 761

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                               V  I+ ++G +     LDRE+   +   + A+D   P   R
Sbjct: 762  ------------------SVISIEPKTGIIKLLNPLDREEQDVHYFSIIASDDGDPA--R 801

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            ++ T  + + + D NDN P+   +     + ED+       +A + A D DVG NS +++
Sbjct: 802  ITVT-NLTITVDDVNDNAPRCVSQVAKARIPEDL--PHGAFVACLAAFDEDVGLNSKLKF 858

Query: 190  AIIGGNTQMQFSIDSLSGDV---SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
             +     ++ F +D  SG +   S    LDY++  ++ L I   D G P  S T  L + 
Sbjct: 859  LL--NAEKVPFRVDHHSGCLLGNSPDVPLDYQKTPNFNLSIEVADHGEPMLSTTCFLEVE 916

Query: 247  IRDVNDN--APRFYTSLFQESVSENVPIGYSIVRVQAYDA--DEGVNAE-LTYTMTDKDY 301
            + DV     A  F     + SV EN  IG  ++ V+A +   ++ V AE L Y +     
Sbjct: 917  LVDVPHKHLAIEFDDVAKEASVYENSEIGTEVIMVEAKEMGDEQKVKAENLEYRIIG--- 973

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG-----GDPPRSATATXXXXX 356
             GN     +ID + G V T+  LDRE ++ Y + V A D       DP R A        
Sbjct: 974  -GNGWPYFSID-QKGTVRTTHILDREKRSAYWITVEARDAKTDFYKDPRRRAVLHVFIRI 1031

Query: 357  XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DN----RLHYEITGGNTRGR 411
                          Y   + E+ P    +V + ATDAD+ DN     L ++I  G+ +  
Sbjct: 1032 LDRNDHRPVAKSAMYIASVLENSPANVVIVKVEATDADDIDNDGAAPLTFKIERGDPQSF 1091

Query: 412  FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVF 469
            F I   +G    +  + LD +++  + L +S  D G        +V + + D N+ AP F
Sbjct: 1092 FRIDLASGYITTSGIRRLDREKQAEHELWISICDGGEPQLCSNVVVIVKVLDENDNAPTF 1151

Query: 470  ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
              A +  +V     IG  +  + A D D G N+ ++Y+         V   D +F I+ +
Sbjct: 1152 TQAMHHYNV-RSKHIG-KLCRIFAVDIDEGENSHLSYN---------VTEGDPRFSID-E 1199

Query: 530  TGAITTNKLLDRETMSGYLLTVTARDGGVPSLS-DTTDVEISVVDVN-------DNEPVF 581
             G I T++ +  +    Y LT+ A D G PS     T V ++ V  +       ++ PV 
Sbjct: 1200 NGNIMTSEAIHSD--ESYALTLQATDHGSPSQQFAATRVVLTAVGSSQKTKKSKNSPPVI 1257

Query: 582  --KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639
              K+  Y   I +   VG +V ++ ATDAD      + + +   D  +  F +   +G +
Sbjct: 1258 SGKKSDYVIPISDADQVGLTVGKLEATDAD---GDDLWWNIFSGD-SDSVFDVRQDTGQL 1313

Query: 640  RTNKALDRESVATHDLKA-VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698
               K +  E +   +L+  +++  G     +TVI+ +    I+   P F ++     +SE
Sbjct: 1314 LLAKKV--ELLKRGELRLNISVTDGQDVDHTTVIIQVS-RQISQR-PAFSANRYDTLVSE 1369

Query: 699  NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758
               +GT I  ++A   + G   +V YS+   DD  +   + R       ++ M  LDYE 
Sbjct: 1370 RVAVGTQIHTLKATGENLGTKPLV-YSLFSIDDI-AMEDKIRVEPSSGNVIVMEPLDYE- 1426

Query: 759  PRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQI-IFNNYKDCFPVGPFGRVP 817
               +   V++     + +  ++ + VTD NDNAP   +     F +  D         V 
Sbjct: 1427 VASQIRAVVQVQQANMKSFSKLILEVTDENDNAPYFVEHTAWAFVDENDSVD-DVLATVT 1485

Query: 818  AYDADVTDK--LQYRILSGNNANLILLNETTGSMTLS 852
            A+D D  D   + Y I+SGN  +L  ++  +G + L+
Sbjct: 1486 AFDRDQDDNGIITYSIVSGNEESLFKIDSHSGEVRLA 1522



 Score =  167 bits (405), Expect = 5e-39
 Identities = 174/769 (22%), Positives = 318/769 (41%), Gaps = 50/769 (6%)

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            R  + +T+ +++ID ND  P F    Y+ S+ E  +  +   +  + ATD D   N  I 
Sbjct: 2486 RRRAFSTLTLSVIDINDKPPFFVLPFYSTSIPE--TAKEGDTVLMVSATDED--ENDTIE 2541

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            Y+++ G     FS+    G +++ K L+++   +  L I+A D  +P    TT + IN+ 
Sbjct: 2542 YSLLDGGESQFFSVHPRQGTITVSKKLEHKAGVTLSLTIKATDSANPPHHATTTVEINVA 2601

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
              +   PRF  S +   V E+  IG  +  VQ  + +     E+ +T+       +  LP
Sbjct: 2602 SESVRVPRFSNSHYLFFVPEDADIGDVVGSVQQMETEID---EVRFTIVPGSEVSDSLLP 2658

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
             +++  +G +     LDRE + ++++ + A   G      T T                 
Sbjct: 2659 FSVERSTGKIIVKSSLDRERRKQWKMTIRADAAGGVHAITTVTLDILDVNDNAPA---FH 2715

Query: 369  GQYE-VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
            G Y+ + ++ED   GT V   +A D D+        +  N    F +   +  G +TVA 
Sbjct: 2716 GDYDKLTISEDATVGTSVTIFSAMDRDDSPSGRIRFSLVNKDPHFEMNGDS--GWLTVAA 2773

Query: 428  PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
            PLD + +  Y L   ATD GG +      I++ D N+  P FE   +   +    P    
Sbjct: 2774 PLDRETQDLYQLIARATDEGGFNTDLSFTISVNDVNDSPPKFEKDEFDVDLL--LPSNAL 2831

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
            +L     D D+  N   +    SE + E V   D +  +  +   I  NK         Y
Sbjct: 2832 ILHFDIKDEDLAPNNH-SLLFISEGNEEGVFWIDSENNLLLKRPEIVENK-------KEY 2883

Query: 548  LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
             L + A DG        T V+I +    D +        T  + E +  GT V   G + 
Sbjct: 2884 SLKIIAFDG---VFEAKTLVKIHLKSKEDVKTRCPDVEKTVILPESSKKGTVV--FGESS 2938

Query: 608  ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA--LDRESVATHDLKAVAIDGGTP 665
                L     ++L  ++  E +FV++  +G+I+  +   +D E     +L  + I G   
Sbjct: 2939 L---LGPNTTFKL-IEEGAENAFVMNFRNGIIKVKEVGQIDYEKTQEFELIRLTIQG--K 2992

Query: 666  PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT----IGEIRAHDPDEGPNAV 721
             +     + +KIE++ND+PP  +   +   I EN P        +  I A D D      
Sbjct: 2993 DELCKERITVKIENLNDNPPKIKEKSVYVSIEENLPTSQDSRQYLTRIAAEDADSDD--- 3049

Query: 722  VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781
            +H+ +   D + +F ++   G     +  +  LD ES    + L   A+     +   + 
Sbjct: 3050 IHFRLL-DDFNKTFEIDEFSG----VVTVLKPLDSESV-SSFNLTAIASDGNFEDKAIIV 3103

Query: 782  ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLIL 841
            + V D NDNAP  +         +         R+ A+  D  + ++Y + + ++   + 
Sbjct: 3104 VTVIDKNDNAPTFEKSTYSMKVMESEAVGYELARLQAFGGDTNETIEYSLKASDHNKFVS 3163

Query: 842  LNETTGSMTLSPQLN-TNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889
            LN   G +TL+  L+   +  L    ++   G+  ++++ Q+ + ++ E
Sbjct: 3164 LNAQNGVLTLAQPLDFETISTLRLTVIAKDSGIPPLESVAQVEISVMDE 3212



 Score =  145 bits (352), Expect = 1e-32
 Identities = 191/779 (24%), Positives = 329/779 (42%), Gaps = 78/779 (10%)

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI----SVTDNPVIAKIK-ATDADVG 182
            D    TA I   II  N + P F ++ Y  +V E++    SV  N  +  +  A+D D G
Sbjct: 1643 DGQQDTAKIVAKIIRTNQHSPVFRKQVYRGTVRENMEPGSSVLSNRHLPLVLLASDEDSG 1702

Query: 183  ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
            +N  + Y ++    +  F++D  SG V   K  D+E+++ +   ++A D G P R +   
Sbjct: 1703 SNGLVGYRMLSKADEEMFTVDQYSGAVRTNKAFDFEKIKEHSFYVQAFDMGQPPRQSLMP 1762

Query: 243  LL--INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
             L  + I D ND  P+F  S   + +        ++V  Q  D  + +   L Y + D  
Sbjct: 1763 ALVVVTISDENDETPKF-ASQSLDVIMLLPTASQAVVGGQMSDDADSIGT-LRYYIKDS- 1819

Query: 301  YTGNVDLPITIDPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDPPRSATATXXXXXXXX 359
                   P ++D ++G V          + K Y + V  TDG     ++           
Sbjct: 1820 -----SSPFSVDSKTGIVSVKDFKAFTNEKKHYNVEVFVTDGNQ--STSYTMKVTTTSTA 1872

Query: 360  XXXXXXFMPGQYEVELAEDE--PPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ 417
                  F   +Y   + E+    PGT ++ +  T    + ++H+ I   N    F I   
Sbjct: 1873 ENSKFKFTRQEYRASIVENSTLTPGTVILPVATTG---EKQVHFTIV--NPHEAFFI--H 1925

Query: 418  NGRGLIT---VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPY 474
            +G G+I+   +A   +     R V+     +   +   A+V I++ + N+ AP F   PY
Sbjct: 1926 HGTGVISATGIAVDCELSPVIRLVVEAKTHEKNPQIAKALVLIDVQNVNDEAPKFIGTPY 1985

Query: 475  TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
            + +V   + IGT +L     D D G +A I+       SN+   +   + V      A  
Sbjct: 1986 SITV-GPSEIGTVILEPKVIDKDEGDHATIS-------SNDMPQYF--KLVGGKVVLAKK 2035

Query: 535  TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
               + D++    + L +   +  V  + +   V I VVD     PVF Q +YTA I +++
Sbjct: 2036 LPAIEDQDLKFSFKL-IAKDNSSVHQVEE--PVVIRVVD--KARPVFSQSMYTAVISKES 2090

Query: 595  LVGTS--VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652
               ++  V  +  +       G I Y +  K      F ID  +G +R  K L+    A 
Sbjct: 2091 TKKSTVLVHVLARSSLQAKSKGLIGYRIIDK---ANLFSIDYVTGEVRL-KNLNGLDAAE 2146

Query: 653  HDLKAVAIDGGTPPQSSTVIVHIKIEDIND-SPPVFESDCLTFYISENSPIGTTIGEIRA 711
            +  +  A +   P  +S   V I ++  +    P F+    +  + E++ IG  I  I +
Sbjct: 2147 YVFEVEAREVTLPKMASRAQVKIVVKSKSAVQKPTFDKQKYSVTVPESASIGQRIITINS 2206

Query: 712  HDPDEGPNAVVHYSIKG-GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770
              PD  PN ++ Y + G  DD   F +++  G    E+     LDYE  +K   LVI  +
Sbjct: 2207 STPD--PNDILQYKLSGTNDDQPMFEIDSETG----EVSVNRHLDYEKVQKYKMLVIATS 2260

Query: 771  SPPLW-NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRV-PAYDADVT---- 824
            S     ++  + +++ DVNDN PV    + +     D    G F  +  A D D T    
Sbjct: 2261 SAKQQSSEADLIVMIEDVNDNMPVFIRPE-VKAEVSDAAISGQFITIMSATDMDTTSSLD 2319

Query: 825  ---DKLQYRILSGNNANLILLNETTGSMTLSPQL-------NTNVPKLATMEVSVTDGV 873
                KL Y+I+ G+   L  ++ +TG ++L+ ++        +  PK   + VSVTDG+
Sbjct: 2320 DPNQKLLYKIVDGDE-TLFNISPSTGEVSLARRIEQEDLTSESEDPK-KVVNVSVTDGM 2376



 Score =  145 bits (351), Expect = 2e-32
 Identities = 187/769 (24%), Positives = 328/769 (42%), Gaps = 77/769 (10%)

Query: 13   VLDCNDHSPVFEMQQYEASVREGASSGTTVLT-------LKATDQDIGKNAEVEYTIELV 65
            ++  N HSPVF  Q Y  +VRE    G++VL+       L A+D+D G N  V Y + L 
Sbjct: 1655 IIRTNQHSPVFRKQVYRGTVRENMEPGSSVLSNRHLPLVLLASDEDSGSNGLVGYRM-LS 1713

Query: 66   TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125
             AD                  +++F +D  SGA+ T  + D EK+  ++  V+A D   P
Sbjct: 1714 KAD------------------EEMFTVDQYSGAVRTNKAFDFEKIKEHSFYVQAFDMGQP 1755

Query: 126  VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
                L   A + V I D+ND  P+F+ ++  V +   +      V+    + DAD  +  
Sbjct: 1756 PRQSL-MPALVVVTISDENDETPKFASQSLDVIM--LLPTASQAVVGGQMSDDAD--SIG 1810

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDY-EQVRSYRLVIRAQDGGSPSRSNTTQLL 244
             +RY I   ++   FS+DS +G VS+     +  + + Y + +   DG   ++S +  + 
Sbjct: 1811 TLRYYI--KDSSSPFSVDSKTGIVSVKDFKAFTNEKKHYNVEVFVTDG---NQSTSYTMK 1865

Query: 245  INIRDVNDNAP-RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
            +      +N+  +F    ++ S+ EN  +    V +      E    ++ +T+       
Sbjct: 1866 VTTTSTAENSKFKFTRQEYRASIVENSTLTPGTVILPVATTGE---KQVHFTIV------ 1916

Query: 304  NVDLPITIDPRSGWVYTSG-QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
            N      I   +G +  +G  +D E     +L+V A      P+ A A            
Sbjct: 1917 NPHEAFFIHHGTGVISATGIAVDCELSPVIRLVVEAKTHEKNPQIAKALVLIDVQNVNDE 1976

Query: 363  XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422
               F+   Y + +   E  GT ++     D DE +  H  I+  +    F +    G+ +
Sbjct: 1977 APKFIGTPYSITVGPSE-IGTVILEPKVIDKDEGD--HATISSNDMPQYFKLV--GGKVV 2031

Query: 423  ITVAQPLDFKQERRYVLTVSATD-SGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
            +    P    Q+ ++   + A D S        V I + D     PVF  + YTA + ++
Sbjct: 2032 LAKKLPAIEDQDLKFSFKLIAKDNSSVHQVEEPVVIRVVD--KARPVFSQSMYTAVISKE 2089

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
            +   +TVLV     S   + A+    +   I ++A       F I+  TG +   K L+ 
Sbjct: 2090 STKKSTVLVHVLARS--SLQAKSKGLIGYRIIDKA-----NLFSIDYVTGEVRL-KNLNG 2141

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVND-NEPVFKQQLYTANIMEDALVGTSV 600
               + Y+  V AR+  +P ++    V+I V   +   +P F +Q Y+  + E A +G  +
Sbjct: 2142 LDAAEYVFEVEAREVTLPKMASRAQVKIVVKSKSAVQKPTFDKQKYSVTVPESASIGQRI 2201

Query: 601  SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
              + ++  D   N  + Y+L   + ++  F ID  +G +  N+ LD E V  + +  +A 
Sbjct: 2202 ITINSSTPDP--NDILQYKLSGTNDDQPMFEIDSETGEVSVNRHLDYEKVQKYKMLVIA- 2258

Query: 661  DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD----- 715
                  QSS   + + IED+ND+ PVF    +   +S+ +  G  I  + A D D     
Sbjct: 2259 TSSAKQQSSEADLIVMIEDVNDNMPVFIRPEVKAEVSDAAISGQFITIMSATDMDTTSSL 2318

Query: 716  EGPNAVVHYSIKGGDDSNSFSLETRQGS-DKAELVTMVDLDYES--PRK 761
            + PN  + Y I  GD++  F++    G    A  +   DL  ES  P+K
Sbjct: 2319 DDPNQKLLYKIVDGDET-LFNISPSTGEVSLARRIEQEDLTSESEDPKK 2366



 Score =  140 bits (339), Expect = 5e-31
 Identities = 125/475 (26%), Positives = 206/475 (43%), Gaps = 25/475 (5%)

Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD-R 326
           E  PIG  + R      +   +  L    +  D + N+ LP TI  +SG +  S +L   
Sbjct: 391 EMAPIGRVLARFNNCTLENPDDVSLM-RFSISDPSSNISLPFTISSKSGVLRVSSKLSIS 449

Query: 327 ETQAKYQLLVT--ATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
           E   K+++ V+     G    R                   +M  Q  + L +   PG  
Sbjct: 450 ERVYKFKVAVSLHGIQGKKDERDVYVEIVDSNNHSPVWSAKWMR-QAPIPLGK---PGDV 505

Query: 385 VVTLTATDADE-DN-RLHYEITG-------GNTRG--RFSITSQNGRGLITV-AQPLDFK 432
           ++ + ATD DE DN R+ Y+I          NT       + +++   ++TV A  L   
Sbjct: 506 LLKVDATDQDEGDNGRVVYKINSEIPFEINANTGEITLIEVPTKSNNWMVTVWAIDLGLP 565

Query: 433 QERRYVLTVSATDSGGRSDTAMVQINITDANN-YAPVFENAPYTASVFEDAPIGTTVLVV 491
             R   L +    +G +       + I ++ N ++PVF + P    V EDAPIGT V  +
Sbjct: 566 LSRMSALNLMFYKNGTKVPAKPKPVIIQESENKHSPVFSSFPEVVEVTEDAPIGTVVAKL 625

Query: 492 SATDSDVGINAQITYSLS--SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
            ++D D G N  I Y +   S  S+E ++  +Q   I     +  T  + +++ +    +
Sbjct: 626 QSSDEDAGYNGLIRYVIQDISGSSHEILSVDEQSGEIT--VASDLTLLMKEKQKVVEIQV 683

Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
            V+A D G P  S T  +++ + DVN++ P F +  Y   I E    G  + +  A D D
Sbjct: 684 KVSAVDAGTPVKSATRTMKLRIKDVNNHSPHFDEPSYYLAISESEKPGKDIFKATANDFD 743

Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669
            G NG+I + L     E     I+P +G+I+    LDRE    H    +A D G P + +
Sbjct: 744 GGNNGKIKFSLGNNGAESSVISIEPKTGIIKLLNPLDREEQDVHYFSIIASDDGDPARIT 803

Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
              + I ++D+ND+ P   S      I E+ P G  +  + A D D G N+ + +
Sbjct: 804 VTNLTITVDDVNDNAPRCVSQVAKARIPEDLPHGAFVACLAAFDEDVGLNSKLKF 858



 Score =  128 bits (308), Expect = 3e-27
 Identities = 211/919 (22%), Positives = 377/919 (41%), Gaps = 85/919 (9%)

Query: 2    SVPFCIHQQINVLDCNDHSPVF-EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEV-- 58
            S PF +  +  ++   D      E + Y   V     + +T  T+K T     +N++   
Sbjct: 1820 SSPFSVDSKTGIVSVKDFKAFTNEKKHYNVEVFVTDGNQSTSYTMKVTTTSTAENSKFKF 1879

Query: 59   ---EYTIELVTADTLNPED-----AXXXXXXXXXXV---QDVFRIDGRSGAL-LTRASLD 106
               EY   +V   TL P       A          +    + F I   +G +  T  ++D
Sbjct: 1880 TRQEYRASIVENSTLTPGTVILPVATTGEKQVHFTIVNPHEAFFIHHGTGVISATGIAVD 1939

Query: 107  REKVARYTVLVKA-TDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISV 165
             E      ++V+A T + +P   +    A + +++ + ND  P+F    Y+++V      
Sbjct: 1940 CELSPVIRLVVEAKTHEKNPQIAK----ALVLIDVQNVNDEAPKFIGTPYSITVGPSEIG 1995

Query: 166  TDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTL----DYEQVR 221
            T   VI + K  D D G      +A I  N   Q+    + G V L K L    D +   
Sbjct: 1996 T---VILEPKVIDKDEGD-----HATISSNDMPQY-FKLVGGKVVLAKKLPAIEDQDLKF 2046

Query: 222  SYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS-ENVPIGYSIVRVQ 280
            S++L+  A+D  S  +       + IR V+   P F  S++   +S E+      +V V 
Sbjct: 2047 SFKLI--AKDNSSVHQVEEP---VVIRVVDKARPVFSQSMYTAVISKESTKKSTVLVHVL 2101

Query: 281  AYDADEGVNAELT-YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTAT 339
            A  + +  +  L  Y + DK    N+    +ID  +G V     L+    A+Y   V A 
Sbjct: 2102 ARSSLQAKSKGLIGYRIIDK---ANL---FSIDYVTGEVRLKN-LNGLDAAEYVFEVEAR 2154

Query: 340  DGGDPPRSATATXXXXXXXXXXXXX-XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR 398
            +   P  ++ A                F   +Y V + E    G  ++T+ ++  D ++ 
Sbjct: 2155 EVTLPKMASRAQVKIVVKSKSAVQKPTFDKQKYSVTVPESASIGQRIITINSSTPDPNDI 2214

Query: 399  LHYEITGGNT-RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR-SDTAMVQ 456
            L Y+++G N  +  F I S+ G   ++V + LD+++ ++Y + V AT S  + S  A + 
Sbjct: 2215 LQYKLSGTNDDQPMFEIDSETGE--VSVNRHLDYEKVQKYKMLVIATSSAKQQSSEADLI 2272

Query: 457  INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA 516
            + I D N+  PVF      A V + A  G  + ++SATD D   +       + ++  + 
Sbjct: 2273 VMIEDVNDNMPVFIRPEVKAEVSDAAISGQFITIMSATDMDTTSSLD---DPNQKLLYKI 2329

Query: 517  VAHHDQQFVINPQTGAITTNKLLDRETMSG------YLLTVTARDGGVPSLSDTTDVEIS 570
            V   +  F I+P TG ++  + +++E ++        ++ V+  DG   + +    V I 
Sbjct: 2330 VDGDETLFNISPSTGEVSLARRIEQEDLTSESEDPKKVVNVSVTDGMFTAYAKLV-VGIL 2388

Query: 571  VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG----LNGRIHYELDPKDRE 626
                    P F+Q  Y A  +E+ +V  S     A    +       G   Y      ++
Sbjct: 2389 RSGKMQPPPKFEQSHYVATALENTIVNKSALLTVAVKGGIPPLRYSLGPAAYSNSSSSKD 2448

Query: 627  EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686
                 ID  +G I  ++ L+  +   + +  V  D       ST+   + + DIND PP 
Sbjct: 2449 SWPVAIDKKTGRIHVSRVLNYHNDKLYQIPLVVEDVTRRRAFSTLT--LSVIDINDKPPF 2506

Query: 687  FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746
            F     +  I E +  G T+  + A D DE  N  + YS+  G +S  FS+  RQG+   
Sbjct: 2507 FVLPFYSTSIPETAKEGDTVLMVSATDEDE--NDTIEYSLLDGGESQFFSVHPRQGT--- 2561

Query: 747  ELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN 803
             +     L++++      L I+A   A+PP      VEI V   +   P   +   +F  
Sbjct: 2562 -ITVSKKLEHKA-GVTLSLTIKATDSANPPHHATTTVEINVASESVRVPRFSNSHYLFFV 2619

Query: 804  YKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILL----NETTGSMTLSPQLNTNV 859
             +D       G V   + ++ D++++ I+ G+  +  LL      +TG + +   L+   
Sbjct: 2620 PEDADIGDVVGSVQQMETEI-DEVRFTIVPGSEVSDSLLPFSVERSTGKIIVKSSLDRER 2678

Query: 860  PK--LATMEVSVTDGVNEI 876
             K    T+      GV+ I
Sbjct: 2679 RKQWKMTIRADAAGGVHAI 2697



 Score = 98.7 bits (235), Expect = 2e-18
 Identities = 79/278 (28%), Positives = 127/278 (45%), Gaps = 18/278 (6%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I+V+D ND++P FE ++Y   V+E +  G  VLT+KA D D      V Y +EL+    
Sbjct: 3206 EISVMDENDNAPKFEKEKYTGKVKENSKVGEKVLTVKAVDADSEHFGAVSYELELIA--- 3262

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                D           V   F I+  +G +L    +D EK  +Y + + A D   P    
Sbjct: 3263 ----DKASDDSLPTTSVTPPFSINA-NGDVLINQPIDYEKTKKYNLKLIAKDGGRP---P 3314

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            L S A + +++ D+NDN P F +   T  V E  S+     + K   +D D   N A   
Sbjct: 3315 LVSEALLDIHVGDENDNAPVFDDCNMTAVVQEGESIGHK--VLKFSISDLDGPTNGAPFT 3372

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
              I G+    F ++    ++   K L++     Y L + A+D  +  +S    L + IR 
Sbjct: 3373 VEIQGDGAKSFKVND-KLELLTAKKLEHRNKDKYLLTVIAKD--TKGKSTDCPLTVFIRQ 3429

Query: 250  VNDNAPRFYTSLFQESVSEN-VPIGYSIVRVQAYDADE 286
             + +AP       Q +  +N +P G  I R++A+D DE
Sbjct: 3430 ASRHAPTMKPMKIQVNTLQNELPEGV-IGRLKAFDEDE 3466



 Score = 71.3 bits (167), Expect = 4e-10
 Identities = 45/132 (34%), Positives = 76/132 (57%), Gaps = 10/132 (7%)

Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQF--SEKTYTVSVDED 162
           L+RE    Y +LVKAT +   +S+ L +TA IH+ +ID ND  P F   E+ Y   +D+D
Sbjct: 109 LNRELKDFYDILVKATCKRRDLSN-LETTARIHLRVIDKNDASPLFLVDEQGYEAVIDDD 167

Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222
                   + +++A+DAD+G NSAI ++++  N    F ++ +SG    ++TL + +   
Sbjct: 168 TEPFST--VLRVEASDADIGINSAIYFSLV--NRSHDFLVEPVSG---WIRTLRHLKPGK 220

Query: 223 YRLVIRAQDGGS 234
           Y L ++A+D  S
Sbjct: 221 YSLKVKAEDRAS 232



 Score = 58.4 bits (135), Expect = 3e-06
 Identities = 37/111 (33%), Positives = 62/111 (55%), Gaps = 7/111 (6%)

Query: 539 LDRETMSGY--LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF--KQQLYTANIMEDA 594
           L+RE    Y  L+  T +   + +L  T  + + V+D ND  P+F   +Q Y A I +D 
Sbjct: 109 LNRELKDFYDILVKATCKRRDLSNLETTARIHLRVIDKNDASPLFLVDEQGYEAVIDDDT 168

Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645
              ++V +V A+DAD+G+N  I++ L  +  +   F+++P SG IRT + L
Sbjct: 169 EPFSTVLRVEASDADIGINSAIYFSLVNRSHD---FLVEPVSGWIRTLRHL 216



 Score = 53.2 bits (122), Expect = 1e-04
 Identities = 70/303 (23%), Positives = 111/303 (36%), Gaps = 38/303 (12%)

Query: 1310 CPEKRSRCSSAPCYNGAEC--SDLWDTYICDCKEGHTGKDC----ADSTGP-----PWRF 1358
            C  + ++CS +PC     C  S    T+ C C  G  G  C      + G          
Sbjct: 3714 CEIETNQCSKSPCEQWQMCIPSVFNSTFECVCPLGMEGDRCLVPSCKNDGKCLEEAELSV 3773

Query: 1359 GGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVM---------SIQLKSGLLHYSYNGE 1409
            GGDG    + L   I+      + ++T   +  +M          ++L +G   Y ++  
Sbjct: 3774 GGDGYFEIS-LSNEIESRMELEIELKTTSPNGIIMWSRGRHDYHMLRLVNGSAQYHWDAG 3832

Query: 1410 T---MYLPMATLSDGAWHRIEIKWLGTDISVTV-DYGLRTVLMPMLANKIQGQYIGKILI 1465
            T   +      + DG WHRI I        +TV D GL     P+ +  +      + L+
Sbjct: 3833 TGTGIVTSKTLIVDGQWHRITISRRQRRTRMTVDDDGLEEAFSPVGSTVVNLHRYSQKLV 3892

Query: 1466 GGLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRPTVR-ENVRDGCQ--SRADCMLSIC 1522
             G     G L   +    GC + + I   + L  R  ++   V+ GC   + + C    C
Sbjct: 3893 LGAKVENGQLTDGI---SGCFRTISIDGIKVLKTRQGMKLFGVQPGCSALTSSPCNDLPC 3949

Query: 1523 PPYSKCVTSWDSS-TCTCEAGRVGPQC---VSACELGPCGAA-RCVPDQTPKGYSCACEP 1577
                 CV+   S   C C +   G  C   +  C   PC    +C+P      Y C C  
Sbjct: 3950 KHGGTCVSHGKSQFVCQCTSRYSGDTCEIDLEPCSSTPCPTGIQCIPFY--NDYLCKCPN 4007

Query: 1578 GYT 1580
            G+T
Sbjct: 4008 GFT 4010



 Score = 48.4 bits (110), Expect = 0.003
 Identities = 42/134 (31%), Positives = 66/134 (49%), Gaps = 18/134 (13%)

Query: 428 PLDFKQERRYVLTVSAT----DSGGRSDTAMVQINITDANNYAPVF--ENAPYTASVFED 481
           PL+ + +  Y + V AT    D      TA + + + D N+ +P+F  +   Y A + +D
Sbjct: 108 PLNRELKDFYDILVKATCKRRDLSNLETTARIHLRVIDKNDASPLFLVDEQGYEAVIDDD 167

Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
               +TVL V A+D+D+GIN+ I +SL +         HD  F++ P +G I T + L  
Sbjct: 168 TEPFSTVLRVEASDADIGINSAIYFSLVNR-------SHD--FLVEPVSGWIRTLRHL-- 216

Query: 542 ETMSGYLLTVTARD 555
                Y L V A D
Sbjct: 217 -KPGKYSLKVKAED 229



 Score = 42.3 bits (95), Expect = 0.19
 Identities = 46/207 (22%), Positives = 89/207 (42%), Gaps = 24/207 (11%)

Query: 149 QFSEKTYTVSVDEDI---SVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205
           +F+   Y +SV+E+        +    KI     +  AN   R A I G     F   + 
Sbjct: 32  EFTAPLYNLSVEENSIGSKYARSENATKIGVPLPEKDANCKFRVAEIAGEKSSLFKAHAR 91

Query: 206 S-GDVSLVKT-------LDYEQVRSYRLVIRA--QDGGSPSRSNTTQLLINIRDVNDNAP 255
             GD   ++        L+ E    Y ++++A  +     +   T ++ + + D ND +P
Sbjct: 92  QVGDFVFLRIRYKGDNPLNRELKDFYDILVKATCKRRDLSNLETTARIHLRVIDKNDASP 151

Query: 256 RFYTSL--FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313
            F      ++  + ++     +++RV+A DAD G+N+ + +++ ++ +         ++P
Sbjct: 152 LFLVDEQGYEAVIDDDTEPFSTVLRVEASDADIGINSAIYFSLVNRSH------DFLVEP 205

Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATD 340
            SGW+ T   L      KY L V A D
Sbjct: 206 VSGWIRTLRHL---KPGKYSLKVKAED 229



 Score = 41.1 bits (92), Expect = 0.43
 Identities = 20/54 (37%), Positives = 35/54 (64%), Gaps = 2/54 (3%)

Query: 11  INVLDCNDHSPVF--EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
           + V+D ND SP+F  + Q YEA + +     +TVL ++A+D DIG N+ + +++
Sbjct: 141 LRVIDKNDASPLFLVDEQGYEAVIDDDTEPFSTVLRVEASDADIGINSAIYFSL 194


>UniRef50_A7S5P0 Cluster: Predicted protein; n=3; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 4639

 Score =  309 bits (759), Expect = 6e-82
 Identities = 243/795 (30%), Positives = 372/795 (46%), Gaps = 64/795 (8%)

Query: 89   VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
            +F I+G +   +    LDRE  A++ + +  T+  +     +     + VN++D ND  P
Sbjct: 858  MFSING-TNLRVGSTPLDRETAAQHILDISLTEGGT-----IKGFVKVTVNVLDINDETP 911

Query: 149  QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
             F   ++ VSV+E   +    V   + ATD D GANSA+ Y+I  GN +  FSI++ +G 
Sbjct: 912  LFQSPSFNVSVNEIERL--GTVFLTVSATDGDAGANSALTYSIAVGNEEGFFSINNKTGA 969

Query: 209  VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268
            +S+ K LD E    Y L + AQDGG P  ++TT + I + D NDN P    ++ Q S+SE
Sbjct: 970  ISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSE 1029

Query: 269  NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328
               I   +  V A D D G N  L Y++ +    G+  +    D  SG +  +G L    
Sbjct: 1030 TAEIDTPVATVIASDKDIGANGRLMYSI-ESGAHGHFRIK---DSSSGAISLAGMLSYNQ 1085

Query: 329  QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388
            +  Y ++V  TDGG P   + A                    Y+V + E E     V+ L
Sbjct: 1086 RNNYIVVVNVTDGGSPALKSRAMVVIDVTPKPRNLT------YDVSVLEGE-ANVQVMDL 1138

Query: 389  TATDADEDNRLHYEITGGNTR---GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445
               ++      H+ ++GGN        S+ S NG  L   + PLD +   +++L +S T+
Sbjct: 1139 KPAES------HFNVSGGNFTFFDSSGSMFSINGTNLRVGSTPLDRETAAQHILDISLTE 1192

Query: 446  SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505
             G       V +N+ D N+  P+F++  +  SV E   +GT  L VSATD D G N+ +T
Sbjct: 1193 GGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALT 1252

Query: 506  YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTT 565
            YS+       A  + +  F IN +TGAI+  K LDRET   Y LTV A+DGG P L+ TT
Sbjct: 1253 YSI-------AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTT 1305

Query: 566  DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625
             V I V D NDN PV +  +   ++ E A + T V+ V A+D D+G NGR+ Y ++    
Sbjct: 1306 AVAIQVGDANDNPPVIQDAVIRVSLSETAEIDTPVATVIASDKDIGANGRLMYSIE--SG 1363

Query: 626  EEGSFVI-DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP 684
              G F I D +SG I     L       + +     DGG+P   S  +V I   D+   P
Sbjct: 1364 AHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVI---DVKPKP 1420

Query: 685  PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS---NSFSLETRQ 741
                   LT+ +S         GE      D  P A  H+++ GG+ +   +S S+ +  
Sbjct: 1421 -----RNLTYDVS------VLEGEANVQVMDLKP-AESHFNVSGGNFTFFDSSGSMFSIN 1468

Query: 742  GSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMK--DFQI 799
            G++    V    LD E+  +    +       +   V+V + V D+ND  P+ +   F +
Sbjct: 1469 GTNLR--VGSTPLDRETAAQHILDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNV 1526

Query: 800  IFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNT 857
              N  +    V  F  V A D D      L Y I +GN      +N  TG+++++ QL+ 
Sbjct: 1527 SVNEIERLGTV--FLTVSATDGDAGANSALTYSIAAGNEEGFFSINNKTGAISVAKQLDR 1584

Query: 858  NVPKLATMEVSVTDG 872
                  T+ V   DG
Sbjct: 1585 ETRDQYTLTVMAQDG 1599



 Score =  301 bits (740), Expect = 1e-79
 Identities = 265/872 (30%), Positives = 403/872 (46%), Gaps = 78/872 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +NVLD ND +P+F+   +  SV E    GT  LT+ ATD D G N+ + Y+I +   +  
Sbjct: 901  VNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAVGNEEGF 960

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F I+ ++GA+     LDRE   +YT+ V A D   P    L
Sbjct: 961  -------------------FSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPP---L 998

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +ST  + + + D NDN P   +    VS+ E   + D PV A + A+D D+GAN  + Y+
Sbjct: 999  NSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEI-DTPV-ATVIASDKDIGANGRLMYS 1056

Query: 191  IIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            I  G     F I DS SG +SL   L Y Q  +Y +V+   DGGSP+  +   ++I++  
Sbjct: 1057 IESG-AHGHFRIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVTP 1115

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
                 PR  T  +  SV E    G + V+V      E          T  D +G++    
Sbjct: 1116 ----KPRNLT--YDVSVLE----GEANVQVMDLKPAESHFNVSGGNFTFFDSSGSMFSIN 1165

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
              + R G    S  LDRET A++ L ++ T+GG        T              F   
Sbjct: 1166 GTNLRVG----STPLDRETAAQHILDISLTEGGTIKGFVKVTVNVLDINDETPL--FQSP 1219

Query: 370  QYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
             + V + E E  GT  +T++ATD D   ++ L Y I  GN  G FSI   N  G I+VA+
Sbjct: 1220 SFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAAGNEEGFFSIN--NKTGAISVAK 1277

Query: 428  PLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
             LD +   +Y LTV A D G    + T  V I + DAN+  PV ++A    S+ E A I 
Sbjct: 1278 QLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSETAEID 1337

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
            T V  V A+D D+G N ++ YS+      E+ AH   Q + +  +GAI+   +L     +
Sbjct: 1338 TPVATVIASDKDIGANGRLMYSI------ESGAHGHFQ-IKDSSSGAISLAGMLSYNQRN 1390

Query: 546  GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
             Y++ V   DGG P+L     V   V+DV   +P  +   Y  +++E       V  +  
Sbjct: 1391 NYIVVVNVTDGGSPALKSRAMV---VIDV---KPKPRNLTYDVSVLEGE-ANVQVMDLKP 1443

Query: 606  TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
             ++   ++G      D      GS      + +   +  LDRE+ A H L     +GGT 
Sbjct: 1444 AESHFNVSGGNFTFFD----SSGSMFSINGTNLRVGSTPLDRETAAQHILDISLTEGGTI 1499

Query: 666  PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
                 V V + + DIND  P+F+S      ++E   +GT    + A D D G N+ + YS
Sbjct: 1500 --KGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYS 1557

Query: 726  IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEI 782
            I  G++   FS+  + G+    +     LD E+ R +Y L + A     PPL +   V I
Sbjct: 1558 IAAGNEEGFFSINNKTGA----ISVAKQLDRET-RDQYTLTVMAQDGGEPPLNSTTAVAI 1612

Query: 783  LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLI 840
             V D NDN PV++D  I  +  +      P   V A D D+    +L Y I SG + +  
Sbjct: 1613 QVGDANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESGAHGHFQ 1672

Query: 841  LLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            + + ++G+++L+  L+ N      + V+VTDG
Sbjct: 1673 IKDSSSGAISLAGMLSYNQRNNYIVVVNVTDG 1704



 Score =  301 bits (739), Expect = 2e-79
 Identities = 242/795 (30%), Positives = 368/795 (46%), Gaps = 64/795 (8%)

Query: 89   VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
            +F I+G +   +    LDRE  A++ + +  T+  +     +     + VN++D ND  P
Sbjct: 3496 MFSING-TNLRVGSTPLDRETAAQHILDISLTEGGT-----IKGFVKVTVNVLDINDETP 3549

Query: 149  QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
             F   ++ VSV+E   +    V   + ATD D GANSA+ Y+I  GN +  FSI++ +G 
Sbjct: 3550 LFQSPSFNVSVNEIERL--GTVFLTVSATDGDAGANSALTYSIAVGNEEGFFSINNKTGA 3607

Query: 209  VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268
            +S+ K LD E    Y L + AQDGG P  ++TT + I + D NDN P    ++ Q S+SE
Sbjct: 3608 ISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSE 3667

Query: 269  NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328
               I   +  V A D D G N  L Y++    + G+  +    D  SG +  +G L    
Sbjct: 3668 TAEIDTPVATVIASDKDIGANGRLMYSIESGAH-GHFRIK---DSSSGAISLAGMLSYNQ 3723

Query: 329  QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388
            +  Y ++V  TDGG P   + A                    Y+V + E E     V+ L
Sbjct: 3724 RNNYIVVVNVTDGGSPALKSRAMVVIDVTPKPRNLT------YDVSVLEGEA-NVQVMDL 3776

Query: 389  TATDADEDNRLHYEITGGNT---RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445
                +      H+ ++GGN        S+ S NG  L   + PLD +   ++VL +S T+
Sbjct: 3777 KPVVS------HFNVSGGNFTFFNSSGSMFSINGNNLSVGSTPLDRETAAQHVLDISLTE 3830

Query: 446  SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505
             G       V +N+ D N+  P+F++  +  SV E   +GT  L VSATD D G N+ +T
Sbjct: 3831 GGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALT 3890

Query: 506  YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTT 565
            YS+       A  + +  F IN +TGAI+  K LDRET   Y LTV A+DGG P L+ TT
Sbjct: 3891 YSI-------AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTT 3943

Query: 566  DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625
             V I V D NDN PV +  +   ++ E A + T V+ V A+D D+G NGR+ Y ++    
Sbjct: 3944 AVAIQVGDANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIE--SG 4001

Query: 626  EEGSFVI-DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP 684
              G F I D +SG I     L       + +     DGG+P   S  +V I   D+   P
Sbjct: 4002 AHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVI---DVTPKP 4058

Query: 685  PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS---NSFSLETRQ 741
                   LT+ +S         GE      D  P A  H++  GG  +   +S S+ +  
Sbjct: 4059 RN-----LTYDVS------VLEGEANVQVMDLKP-AESHFNASGGTFAFFGSSGSMFSIN 4106

Query: 742  GSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKD--FQI 799
            G++    V    LD E+  +    +       +    +V + V D+ND  P  +   F +
Sbjct: 4107 GTNLR--VGSTPLDRETAEEHVLDISLTEGGIVKGLFKVTVNVLDINDETPSFQSPSFNV 4164

Query: 800  IFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNT 857
              N  +    V  F  V A D+D      L Y I +GN   +  +N  T +++++ QL+ 
Sbjct: 4165 SVNEIERLGTV--FLTVSATDSDAGANSALTYSIAAGNEEGVFSINNKTAAISVAKQLDR 4222

Query: 858  NVPKLATMEVSVTDG 872
                L  + V   DG
Sbjct: 4223 ETRDLYMLTVMAQDG 4237



 Score =  295 bits (723), Expect = 1e-77
 Identities = 211/661 (31%), Positives = 320/661 (48%), Gaps = 42/661 (6%)

Query: 89   VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
            +F I+G + ++ +   LDRE  A++ + +  T+  +     +     + VN++D ND  P
Sbjct: 3799 MFSINGNNLSVGS-TPLDRETAAQHVLDISLTEGGT-----IKGFVKVTVNVLDINDETP 3852

Query: 149  QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
             F   ++ VSV+E   +    V   + ATD D GANSA+ Y+I  GN +  FSI++ +G 
Sbjct: 3853 LFQSPSFNVSVNEIERL--GTVFLTVSATDGDAGANSALTYSIAAGNEEGFFSINNKTGA 3910

Query: 209  VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268
            +S+ K LD E    Y L + AQDGG P  ++TT + I + D NDN P    ++ + S+SE
Sbjct: 3911 ISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSE 3970

Query: 269  NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328
               I   +  V A D D G N  L Y++    + G+  +    D  SG +  +G L    
Sbjct: 3971 TAAIDTPVATVIASDKDIGANGRLMYSIESGAH-GHFQIK---DSSSGAISLAGMLSYNQ 4026

Query: 329  QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388
            +  Y ++V  TDGG P   + A                    Y+V + E E     V+ L
Sbjct: 4027 RNNYIVVVNVTDGGSPALKSRAMVVIDVTPKPRNLT------YDVSVLEGEA-NVQVMDL 4079

Query: 389  TATDADEDNRLHYEITGGNTR---GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445
               ++      H+  +GG         S+ S NG  L   + PLD +    +VL +S T+
Sbjct: 4080 KPAES------HFNASGGTFAFFGSSGSMFSINGTNLRVGSTPLDRETAEEHVLDISLTE 4133

Query: 446  SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505
             G       V +N+ D N+  P F++  +  SV E   +GT  L VSATDSD G N+ +T
Sbjct: 4134 GGIVKGLFKVTVNVLDINDETPSFQSPSFNVSVNEIERLGTVFLTVSATDSDAGANSALT 4193

Query: 506  YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTT 565
            YS+       A  + +  F IN +T AI+  K LDRET   Y+LTV A+DGG PSL+ T 
Sbjct: 4194 YSI-------AAGNEEGVFSINNKTAAISVAKQLDRETRDLYMLTVMAQDGGEPSLNRTA 4246

Query: 566  DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625
             V I V D NDN PV +  +   ++ E A + T V+ V A+D D+G NGR+ Y ++    
Sbjct: 4247 AVPIQVGDANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIE--SG 4304

Query: 626  EEGSFVI-DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI--ND 682
              G F I D +SG I     L  +    + +     DGG+    S  IV I +     N 
Sbjct: 4305 AHGHFQIKDSSSGAISVAGRLSYKQRNNYSVVVKVTDGGSLALESRAIVLIDVTPTTENR 4364

Query: 683  SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
            + PVF S      + +++     +  + A D D G N VV Y I   +D++ F +E   G
Sbjct: 4365 NAPVFASVQYIGGVYKDTSFDFPVLTVVATDSDTGINGVVEYRI--SEDTDLFYIEPTSG 4422

Query: 743  S 743
            +
Sbjct: 4423 T 4423



 Score =  266 bits (651), Expect = 8e-69
 Identities = 251/857 (29%), Positives = 384/857 (44%), Gaps = 94/857 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND+ PV +    + S+ E A   T V T+ A+D+DIG N  + Y+IE       
Sbjct: 3644 IQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGANGRLMYSIE------- 3696

Query: 71   NPEDAXXXXXXXXXXVQDVFRI-DGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                               FRI D  SGA+     L   +   Y V+V  TD  SP    
Sbjct: 3697 -------------SGAHGHFRIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPA--- 3740

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE---DISVTD-NPVIAKIKATDADVGANS 185
            L S A + +++       P+    TY VSV E   ++ V D  PV++    +    G N 
Sbjct: 3741 LKSRAMVVIDVT------PKPRNLTYDVSVLEGEANVQVMDLKPVVSHFNVS----GGN- 3789

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
               +     +  M FSI+    ++S+  T LD E    + L I   +GG+       ++ 
Sbjct: 3790 ---FTFFNSSGSM-FSING--NNLSVGSTPLDRETAAQHVLDISLTEGGTIK--GFVKVT 3841

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
            +N+ D+ND  P F +  F  SV+E   +G   + V A D D G N+ LTY++      GN
Sbjct: 3842 VNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIA----AGN 3897

Query: 305  VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
             +   +I+ ++G +  + QLDRET+ +Y L V A DGG+PP ++T               
Sbjct: 3898 EEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPP 3957

Query: 365  XFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGL 422
                    V L+E     TPV T+ A+D D   + RL Y I  G   G F I   +  G 
Sbjct: 3958 VIQDAVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESG-AHGHFQIKDSSS-GA 4015

Query: 423  ITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFE 480
            I++A  L + Q   Y++ V+ TD G  +    AMV I++T      P   N  Y  SV E
Sbjct: 4016 ISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVT------PKPRNLTYDVSVLE 4069

Query: 481  DAPIGTTVLVVSATDSDVGINAQI-TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
                   V V+    ++   NA   T++      +         F IN  T     +  L
Sbjct: 4070 GE---ANVQVMDLKPAESHFNASGGTFAFFGSSGS--------MFSING-TNLRVGSTPL 4117

Query: 540  DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
            DRET   ++L ++  +GG+  +     V ++V+D+ND  P F+   +  ++ E   +GT 
Sbjct: 4118 DRETAEEHVLDISLTEGGI--VKGLFKVTVNVLDINDETPSFQSPSFNVSVNEIERLGTV 4175

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
               V ATD+D G N  + Y +     EEG F I+  +  I   K LDRE+   + L  +A
Sbjct: 4176 FLTVSATDSDAGANSALTYSI-AAGNEEGVFSINNKTAAISVAKQLDRETRDLYMLTVMA 4234

Query: 660  IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
             DGG P  + T  V I++ D ND+PPV +   +   +SE + I T +  + A D D G N
Sbjct: 4235 QDGGEPSLNRTAAVPIQVGDANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKDIGAN 4294

Query: 720  AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP-PLWNDV 778
              + YSI+ G   + F ++    S    +     L Y+  R  Y +V++      L  + 
Sbjct: 4295 GRLMYSIESGAHGH-FQIKD---SSSGAISVAGRLSYKQ-RNNYSVVVKVTDGGSLALES 4349

Query: 779  RVEILV----TDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRIL 832
            R  +L+    T  N NAPV    Q I   YKD     P   V A D+D  +   ++YRI 
Sbjct: 4350 RAIVLIDVTPTTENRNAPVFASVQYIGGVYKDTSFDFPVLTVVATDSDTGINGVVEYRI- 4408

Query: 833  SGNNANLILLNETTGSM 849
               + +L  +  T+G++
Sbjct: 4409 -SEDTDLFYIEPTSGTI 4424



 Score =  258 bits (633), Expect = 1e-66
 Identities = 232/784 (29%), Positives = 351/784 (44%), Gaps = 78/784 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND+ PV +    + S+ E A   T V T+ A+D+DIG N  + Y+IE       
Sbjct: 1006 IQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGANGRLMYSIE------- 1058

Query: 71   NPEDAXXXXXXXXXXVQDVFRI-DGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                               FRI D  SGA+     L   +   Y V+V  TD  SP    
Sbjct: 1059 -------------SGAHGHFRIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPA--- 1102

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            L S A + +++       P+    TY VSV E  +   N  +  +K  ++    +    +
Sbjct: 1103 LKSRAMVVIDVT------PKPRNLTYDVSVLEGEA---NVQVMDLKPAESHFNVSGG-NF 1152

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
                 +  M FSI+  +  V     LD E    + L I   +GG+       ++ +N+ D
Sbjct: 1153 TFFDSSGSM-FSINGTNLRVGSTP-LDRETAAQHILDISLTEGGTIK--GFVKVTVNVLD 1208

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            +ND  P F +  F  SV+E   +G   + V A D D G N+ LTY++      GN +   
Sbjct: 1209 INDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIA----AGNEEGFF 1264

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            +I+ ++G +  + QLDRET+ +Y L V A DGG+PP ++T                    
Sbjct: 1265 SINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDA 1324

Query: 370  QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
               V L+E     TPV T+ A+D D   + RL Y I  G   G F I   +  G I++A 
Sbjct: 1325 VIRVSLSETAEIDTPVATVIASDKDIGANGRLMYSIESG-AHGHFQIKDSSS-GAISLAG 1382

Query: 428  PLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
             L + Q   Y++ V+ TD G  +    AMV I++       P   N  Y  SV E     
Sbjct: 1383 MLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVK------PKPRNLTYDVSVLE-GEAN 1435

Query: 486  TTVLVVSATDSDVGINA-QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
              V+ +   +S   ++    T+  SS             F IN  T     +  LDRET 
Sbjct: 1436 VQVMDLKPAESHFNVSGGNFTFFDSS----------GSMFSING-TNLRVGSTPLDRETA 1484

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
            + ++L ++  +GG  ++     V ++V+D+ND  P+F+   +  ++ E   +GT    V 
Sbjct: 1485 AQHILDISLTEGG--TIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVS 1542

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            ATD D G N  + Y +     EEG F I+  +G I   K LDRE+   + L  +A DGG 
Sbjct: 1543 ATDGDAGANSALTYSI-AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGE 1601

Query: 665  PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
            PP +ST  V I++ D ND+PPV +   +   +SE + I T +  + A D D G N  + Y
Sbjct: 1602 PPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKDIGANGRLMY 1661

Query: 725  SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR---AASPPLWNDVRVE 781
            SI+ G   + F ++    S    L  M  L Y + R  Y +V+      SP L +   V 
Sbjct: 1662 SIESGAHGH-FQIKD-SSSGAISLAGM--LSY-NQRNNYIVVVNVTDGGSPALKSRAMVV 1716

Query: 782  ILVT 785
            I VT
Sbjct: 1717 IDVT 1720



 Score =  254 bits (621), Expect = 3e-65
 Identities = 217/681 (31%), Positives = 313/681 (45%), Gaps = 61/681 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +NVLD ND +P+F+   +  SV E    GT  LT+ ATD D G N+ + Y+I        
Sbjct: 3842 VNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-------- 3893

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                            +  F I+ ++GA+     LDRE   +YT+ V A D   P    L
Sbjct: 3894 -----------AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPP---L 3939

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +ST  + + + D NDN P   +    VS+ E  ++ D PV A + A+D D+GAN  + Y+
Sbjct: 3940 NSTTAVAIQVGDANDNPPVIQDAVIRVSLSETAAI-DTPV-ATVIASDKDIGANGRLMYS 3997

Query: 191  IIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            I  G     F I DS SG +SL   L Y Q  +Y +V+   DGGSP+  +   ++I++  
Sbjct: 3998 IESG-AHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVTP 4056

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
                 PR  T  +  SV E    G + V+V      E        T      +G++    
Sbjct: 4057 ----KPRNLT--YDVSVLE----GEANVQVMDLKPAESHFNASGGTFAFFGSSGSMFSIN 4106

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
              + R G    S  LDRET  ++ L ++ T+GG        T              F   
Sbjct: 4107 GTNLRVG----STPLDRETAEEHVLDISLTEGGIVKGLFKVTVNVLDINDETPS--FQSP 4160

Query: 370  QYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
             + V + E E  GT  +T++ATD+D   ++ L Y I  GN  G FSI   N    I+VA+
Sbjct: 4161 SFNVSVNEIERLGTVFLTVSATDSDAGANSALTYSIAAGNEEGVFSI--NNKTAAISVAK 4218

Query: 428  PLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
             LD +    Y+LTV A D G  S   TA V I + DAN+  PV ++A    S+ E A I 
Sbjct: 4219 QLDRETRDLYMLTVMAQDGGEPSLNRTAAVPIQVGDANDNPPVIQDAVIRVSLSETAAID 4278

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
            T V  V A+D D+G N ++ YS+      E+ AH   Q + +  +GAI+    L  +  +
Sbjct: 4279 TPVATVIASDKDIGANGRLMYSI------ESGAHGHFQ-IKDSSSGAISVAGRLSYKQRN 4331

Query: 546  GYLLTVTARDGGVPSLSDTTDVEISVVDV--NDNEPVFKQQLYTANIMEDALVGTSVSQV 603
             Y + V   DGG  +L     V I V     N N PVF    Y   + +D      V  V
Sbjct: 4332 NYSVVVKVTDGGSLALESRAIVLIDVTPTTENRNAPVFASVQYIGGVYKDTSFDFPVLTV 4391

Query: 604  GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL-DRESVATHDLKAVAIDG 662
             ATD+D G+NG + Y +     +   F I+P SG IRT     D++   +      A D 
Sbjct: 4392 VATDSDTGINGVVEYRI---SEDTDLFYIEPTSGTIRTADIFADKDRGLSFSFMVQASDK 4448

Query: 663  GTPPQSSTVIVHIKIEDINDS 683
            GTPP+ +    HI I  + DS
Sbjct: 4449 GTPPKKTKENAHITIFLLRDS 4469



 Score =  243 bits (595), Expect = 5e-62
 Identities = 222/759 (29%), Positives = 340/759 (44%), Gaps = 78/759 (10%)

Query: 36   ASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRI-DG 94
            A   T V T+ A+D+DIG N  + Y+IE                          F+I D 
Sbjct: 3366 AEIDTPVATVIASDKDIGANGRLMYSIE--------------------SGAHGHFQIKDS 3405

Query: 95   RSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKT 154
             SGA+     L   +   Y V+V  TD  SP    L S A + +++       P+    T
Sbjct: 3406 SSGAISLAGMLSYNQRNNYIVVVNVTDGGSPA---LKSRAMVVIDV------KPKPRNLT 3456

Query: 155  YTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT 214
            Y VSV E  +   N  +  +K  ++    +    +     +  M FSI+  +  V     
Sbjct: 3457 YDVSVLEGEA---NVQVMDLKPAESHFNVSGG-NFTFFDSSGSM-FSINGTNLRVGSTP- 3510

Query: 215  LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY 274
            LD E    + L I   +GG+       ++ +N+ D+ND  P F +  F  SV+E   +G 
Sbjct: 3511 LDRETAAQHILDISLTEGGTIK--GFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGT 3568

Query: 275  SIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQL 334
              + V A D D G N+ LTY++      GN +   +I+ ++G +  + QLDRET+ +Y L
Sbjct: 3569 VFLTVSATDGDAGANSALTYSIA----VGNEEGFFSINNKTGAISVAKQLDRETRDQYTL 3624

Query: 335  LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394
             V A DGG+PP ++T                      +V L+E     TPV T+ A+D D
Sbjct: 3625 TVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKD 3684

Query: 395  --EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS-- 450
               + RL Y I  G   G F I   +  G I++A  L + Q   Y++ V+ TD G  +  
Sbjct: 3685 IGANGRLMYSIESG-AHGHFRIKDSSS-GAISLAGMLSYNQRNNYIVVVNVTDGGSPALK 3742

Query: 451  DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA-QITYSLS 509
              AMV I++T      P   N  Y  SV E       V+ +    S   ++    T+  S
Sbjct: 3743 SRAMVVIDVT------PKPRNLTYDVSVLE-GEANVQVMDLKPVVSHFNVSGGNFTFFNS 3795

Query: 510  SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569
            S             F IN    ++ +  L DRET + ++L ++  +GG  ++     V +
Sbjct: 3796 S----------GSMFSINGNNLSVGSTPL-DRETAAQHVLDISLTEGG--TIKGFVKVTV 3842

Query: 570  SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629
            +V+D+ND  P+F+   +  ++ E   +GT    V ATD D G N  + Y +     EEG 
Sbjct: 3843 NVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-AAGNEEGF 3901

Query: 630  FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES 689
            F I+  +G I   K LDRE+   + L  +A DGG PP +ST  V I++ D ND+PPV + 
Sbjct: 3902 FSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQD 3961

Query: 690  DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV 749
              +   +SE + I T +  + A D D G N  + YSI+ G   + F ++    S    L 
Sbjct: 3962 AVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESGAHGH-FQIKD-SSSGAISLA 4019

Query: 750  TMVDLDYESPRKKYELVIR---AASPPLWNDVRVEILVT 785
             M  L Y + R  Y +V+      SP L +   V I VT
Sbjct: 4020 GM--LSY-NQRNNYIVVVNVTDGGSPALKSRAMVVIDVT 4055



 Score =  241 bits (590), Expect = 2e-61
 Identities = 223/819 (27%), Positives = 358/819 (43%), Gaps = 68/819 (8%)

Query: 89   VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
            +F I+G +   +    LDRE  A++ + +  T+  +     +     + VN++D ND  P
Sbjct: 616  MFSING-TNLRVGSTPLDRETAAQHILDISLTEGGT-----IKGFVKVTVNVLDINDETP 669

Query: 149  QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
             F   ++ VSV+E   +    V   + ATD D GANSA+ Y+I  GN +  FSI++ +G 
Sbjct: 670  LFQSPSFNVSVNEIERL--GTVFLTVSATDGDAGANSALTYSIAAGNEEGFFSINNKTGA 727

Query: 209  VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268
            +S+ K LD E    Y L + AQDGG P  ++TT + I + D NDN P    ++ + S+SE
Sbjct: 728  ISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSE 787

Query: 269  ---NVPIGYSIV---RVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322
               NV  G S     R             LTY ++  +   NV +       S +  + G
Sbjct: 788  VVVNVTDGGSPALKSRAMVVIDVTPKPRNLTYDVSVLEGEANVQVMDLKPAESHFNVSGG 847

Query: 323  QLDRETQAKYQLLVTATD---GGDPPRSATAT--XXXXXXXXXXXXXXFMPGQYEVELAE 377
                   +     +  T+   G  P    TA                 F+     V    
Sbjct: 848  NFTFFDSSGSMFSINGTNLRVGSTPLDRETAAQHILDISLTEGGTIKGFVKVTVNVLDIN 907

Query: 378  DEPP--GTPVVTLTATDADEDNRLHYEIT------GGNTRGRFSITSQNGRGLITV---- 425
            DE P   +P   ++  + +    +   ++      G N+   +SI   N  G  ++    
Sbjct: 908  DETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAVGNEEGFFSINNKT 967

Query: 426  -----AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASV 478
                 A+ LD +   +Y LTV A D G    + T  V I + DAN+  PV ++A    S+
Sbjct: 968  GAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSL 1027

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             E A I T V  V A+D D+G N ++ YS+ S         H    + +  +GAI+   +
Sbjct: 1028 SETAEIDTPVATVIASDKDIGANGRLMYSIES-------GAHGHFRIKDSSSGAISLAGM 1080

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            L     + Y++ V   DGG P+L     V   V+DV    P  +   Y  +++E      
Sbjct: 1081 LSYNQRNNYIVVVNVTDGGSPALKSRAMV---VIDVT---PKPRNLTYDVSVLEGE-ANV 1133

Query: 599  SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
             V  +   ++   ++G      D      GS      + +   +  LDRE+ A H L   
Sbjct: 1134 QVMDLKPAESHFNVSGGNFTFFD----SSGSMFSINGTNLRVGSTPLDRETAAQHILDIS 1189

Query: 659  AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
              +GGT      V V + + DIND  P+F+S      ++E   +GT    + A D D G 
Sbjct: 1190 LTEGGT--IKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGA 1247

Query: 719  NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLW 775
            N+ + YSI  G++   FS+  + G+    +     LD E+ R +Y L + A     PPL 
Sbjct: 1248 NSALTYSIAAGNEEGFFSINNKTGA----ISVAKQLDRET-RDQYTLTVMAQDGGEPPLN 1302

Query: 776  NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILS 833
            +   V I V D NDN PV++D  I  +  +      P   V A D D+    +L Y I S
Sbjct: 1303 STTAVAIQVGDANDNPPVIQDAVIRVSLSETAEIDTPVATVIASDKDIGANGRLMYSIES 1362

Query: 834  GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            G + +  + + ++G+++L+  L+ N      + V+VTDG
Sbjct: 1363 GAHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDG 1401



 Score =  234 bits (573), Expect = 2e-59
 Identities = 211/750 (28%), Positives = 329/750 (43%), Gaps = 76/750 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +NVLD ND +P+F+   +  SV E    GT  LT+ ATD D G N+ + Y+I        
Sbjct: 659  VNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-------- 710

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                            +  F I+ ++GA+     LDRE   +YT+ V A D   P    L
Sbjct: 711  -----------AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEP---PL 756

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDE-DISVTD--NPVIAKIKATDADV---GAN 184
            +ST  + + + D NDN P   +    VS+ E  ++VTD  +P +        DV     N
Sbjct: 757  NSTTAVAIQVGDANDNPPVIQDAVIRVSLSEVVVNVTDGGSPALKSRAMVVIDVTPKPRN 816

Query: 185  SAIRYAIIGG--NTQ-MQFSIDSLSGDVSLVKTLDYEQVRSYRLV--IRAQDGGSP-SRS 238
                 +++ G  N Q M         +VS      ++   S   +     + G +P  R 
Sbjct: 817  LTYDVSVLEGEANVQVMDLKPAESHFNVSGGNFTFFDSSGSMFSINGTNLRVGSTPLDRE 876

Query: 239  NTTQLLINIRDVNDNAPRFYTSLFQE--SVSENVPIGYS-IVRVQAYDADEGVNAELTYT 295
               Q +++I        + +  +      +++  P+  S    V   + +      LT +
Sbjct: 877  TAAQHILDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVS 936

Query: 296  MTDKDYTGNVDLPITI-----------DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP 344
             TD D   N  L  +I           + ++G +  + QLDRET+ +Y L V A DGG+P
Sbjct: 937  ATDGDAGANSALTYSIAVGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEP 996

Query: 345  PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYE 402
            P ++T                      +V L+E     TPV T+ A+D D   + RL Y 
Sbjct: 997  PLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGANGRLMYS 1056

Query: 403  ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINIT 460
            I  G   G F I   +  G I++A  L + Q   Y++ V+ TD G  +    AMV I++T
Sbjct: 1057 IESG-AHGHFRI-KDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVT 1114

Query: 461  DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN-AQITYSLSSEISNEAVAH 519
                  P   N  Y  SV E       V+ +   +S   ++    T+  SS         
Sbjct: 1115 ------PKPRNLTYDVSVLE-GEANVQVMDLKPAESHFNVSGGNFTFFDSS--------- 1158

Query: 520  HDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP 579
                F IN  T     +  LDRET + ++L ++  +GG  ++     V ++V+D+ND  P
Sbjct: 1159 -GSMFSIN-GTNLRVGSTPLDRETAAQHILDISLTEGG--TIKGFVKVTVNVLDINDETP 1214

Query: 580  VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639
            +F+   +  ++ E   +GT    V ATD D G N  + Y +     EEG F I+  +G I
Sbjct: 1215 LFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-AAGNEEGFFSINNKTGAI 1273

Query: 640  RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699
               K LDRE+   + L  +A DGG PP +ST  V I++ D ND+PPV +   +   +SE 
Sbjct: 1274 SVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSET 1333

Query: 700  SPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729
            + I T +  + A D D G N  + YSI+ G
Sbjct: 1334 AEIDTPVATVIASDKDIGANGRLMYSIESG 1363



 Score =  233 bits (570), Expect = 5e-59
 Identities = 214/716 (29%), Positives = 327/716 (45%), Gaps = 55/716 (7%)

Query: 167  DNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSYRL 225
            D PV A + A+D D+GAN  + Y+I  G     F I DS SG +SL   L Y Q  +Y +
Sbjct: 3369 DTPV-ATVIASDKDIGANGRLMYSIESG-AHGHFQIKDSSSGAISLAGMLSYNQRNNYIV 3426

Query: 226  VIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD 285
            V+   DGGSP+  +   ++I+++      PR  T  +  SV E    G + V+V      
Sbjct: 3427 VVNVTDGGSPALKSRAMVVIDVKP----KPRNLT--YDVSVLE----GEANVQVMDLKPA 3476

Query: 286  EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP 345
            E          T  D +G++      + R G    S  LDRET A++ L ++ T+GG   
Sbjct: 3477 ESHFNVSGGNFTFFDSSGSMFSINGTNLRVG----STPLDRETAAQHILDISLTEGGTIK 3532

Query: 346  RSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI 403
                 T              F    + V + E E  GT  +T++ATD D   ++ L Y I
Sbjct: 3533 GFVKVTVNVLDINDETPL--FQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI 3590

Query: 404  TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITD 461
              GN  G FSI   N  G I+VA+ LD +   +Y LTV A D G    + T  V I + D
Sbjct: 3591 AVGNEEGFFSIN--NKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGD 3648

Query: 462  ANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521
            AN+  PV ++A    S+ E A I T V  V A+D D+G N ++ YS+ S         H 
Sbjct: 3649 ANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGANGRLMYSIES-------GAHG 3701

Query: 522  QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581
               + +  +GAI+   +L     + Y++ V   DGG P+L     V   V+DV    P  
Sbjct: 3702 HFRIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMV---VIDVT---PKP 3755

Query: 582  KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641
            +   Y  +++E       V  +    +   ++G      +      GS      + +   
Sbjct: 3756 RNLTYDVSVLEGE-ANVQVMDLKPVVSHFNVSGGNFTFFN----SSGSMFSINGNNLSVG 3810

Query: 642  NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701
            +  LDRE+ A H L     +GGT      V V + + DIND  P+F+S      ++E   
Sbjct: 3811 STPLDRETAAQHVLDISLTEGGTI--KGFVKVTVNVLDINDETPLFQSPSFNVSVNEIER 3868

Query: 702  IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761
            +GT    + A D D G N+ + YSI  G++   FS+  + G+    +     LD E+ R 
Sbjct: 3869 LGTVFLTVSATDGDAGANSALTYSIAAGNEEGFFSINNKTGA----ISVAKQLDRET-RD 3923

Query: 762  KYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA 818
            +Y L + A     PPL +   V I V D NDN PV++D  I  +  +      P   V A
Sbjct: 3924 QYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSETAAIDTPVATVIA 3983

Query: 819  YDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
             D D+    +L Y I SG + +  + + ++G+++L+  L+ N      + V+VTDG
Sbjct: 3984 SDKDIGANGRLMYSIESGAHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDG 4039



 Score =  232 bits (568), Expect = 9e-59
 Identities = 242/898 (26%), Positives = 384/898 (42%), Gaps = 85/898 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND+ PV +    + S+ E A   T V T+ A+D+DIG N  + Y+IE       
Sbjct: 3086 IQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGANGRLMYSIESGALGHF 3145

Query: 71   NPEDAXXXXXXXXXXVQDVFR---------IDGRSGALLTRASLDRE---KVARYTVLVK 118
              +D           +    R          DG S AL +RA +  +   K    T  V 
Sbjct: 3146 QIKDWSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAIVVIDVTPKPRNLTHDVS 3205

Query: 119  ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178
              +  + V       A  H N+   N  +   S   ++++   ++ V   P+  +  A  
Sbjct: 3206 VLEGEANVQVMDLKPAESHFNVSGGNFTFFDSSGSMFSIN-GTNLRVGSTPLDRETAAQH 3264

Query: 179  A-DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSL-------VKTLDYEQVRSYRLVIRAQ 230
              D+          I G  ++  ++  ++ +  L       V   + E++ +  L + A 
Sbjct: 3265 ILDISLTEG---GTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSAT 3321

Query: 231  DGGSPSRSNTTQLLI--NIRDVNDNAPRFYTSLFQES---VSENVPIGYSIVRVQAYDAD 285
            DG + + S  T  +   N   + +     Y++LF  S    S+   I   +  V A D D
Sbjct: 3322 DGDAGANSALTYSIAAGNEEGLVERTILKYSNLFDFSDLFCSQTAEIDTPVATVIASDKD 3381

Query: 286  EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP 345
             G N  L Y++    + G+  +    D  SG +  +G L    +  Y ++V  TDGG P 
Sbjct: 3382 IGANGRLMYSIESGAH-GHFQIK---DSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPA 3437

Query: 346  RSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITG 405
              + A                    Y+V + E E     V+ L   ++      H+ ++G
Sbjct: 3438 LKSRAMVVIDVKPKPRNLT------YDVSVLEGEA-NVQVMDLKPAES------HFNVSG 3484

Query: 406  GNTR---GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDA 462
            GN        S+ S NG  L   + PLD +   +++L +S T+ G       V +N+ D 
Sbjct: 3485 GNFTFFDSSGSMFSINGTNLRVGSTPLDRETAAQHILDISLTEGGTIKGFVKVTVNVLDI 3544

Query: 463  NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522
            N+  P+F++  +  SV E   +GT  L VSATD D G N+ +TYS+       AV + + 
Sbjct: 3545 NDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-------AVGNEEG 3597

Query: 523  QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582
             F IN +TGAI+  K LDRET   Y LTV A+DGG P L+ TT V I V D NDN PV +
Sbjct: 3598 FFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQ 3657

Query: 583  QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI-DPASGVIRT 641
              +   ++ E A + T V+ V A+D D+G NGR+ Y ++      G F I D +SG I  
Sbjct: 3658 DAVIQVSLSETAEIDTPVATVIASDKDIGANGRLMYSIE--SGAHGHFRIKDSSSGAISL 3715

Query: 642  NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701
               L       + +     DGG+P   S  +V I   D+   P       LT+ +S    
Sbjct: 3716 AGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVI---DVTPKP-----RNLTYDVS---- 3763

Query: 702  IGTTIGEIRAHDPDEGPNAVVHYSIKGGD---DSNSFSLETRQGSDKAELVTMVDLDYES 758
                 GE      D  P  V H+++ GG+    ++S S+ +  G++ +  V    LD E+
Sbjct: 3764 --VLEGEANVQVMDLKP-VVSHFNVSGGNFTFFNSSGSMFSINGNNLS--VGSTPLDRET 3818

Query: 759  PRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMK--DFQIIFNNYKDCFPVGPFGRV 816
              +    +       +   V+V + V D+ND  P+ +   F +  N  +    V  F  V
Sbjct: 3819 AAQHVLDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTV--FLTV 3876

Query: 817  PAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
             A D D      L Y I +GN      +N  TG+++++ QL+       T+ V   DG
Sbjct: 3877 SATDGDAGANSALTYSIAAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDG 3934



 Score =  222 bits (543), Expect = 1e-55
 Identities = 145/435 (33%), Positives = 216/435 (49%), Gaps = 28/435 (6%)

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            +++ G   +Q  +D  +G +S+ K LD E    Y L + AQDGG P  ++TT + I + D
Sbjct: 1731 SVLEGEANVQV-MDLKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGD 1789

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
             NDN P    ++ + S+SE   I   +  V A D D G N  L Y++    + G+  +  
Sbjct: 1790 ANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESGAH-GHFQIK- 1847

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
              D  SG +  +G L    +  Y ++V  TDGG P   + A                   
Sbjct: 1848 --DSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVTPKPRNLT----- 1900

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT---RGRFSITSQNGRGLITVA 426
             Y+V + E E     V+ L    +      H+ ++GGN        S+ S NG  L   +
Sbjct: 1901 -YDVSVLEGEA-NVQVMDLKPVVS------HFNVSGGNFTFFNSSGSMFSINGNNLRVGS 1952

Query: 427  QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
             PLD +   ++VL +S T+ G       V +N+ D N+  P+F++  +  SV E   +GT
Sbjct: 1953 TPLDRETAAQHVLDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGT 2012

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
              L VSATD D G N+ +TYS+       A  + +  F IN +TGAI+  K LDRET   
Sbjct: 2013 VFLTVSATDGDAGANSALTYSI-------AAGNEEGFFSINNKTGAISVAKQLDRETRDQ 2065

Query: 547  YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
            Y LTV A+DGG P L+ TT V I V D NDN PV +  +   ++ E A + T V+ V A+
Sbjct: 2066 YTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSETAEIDTPVATVIAS 2125

Query: 607  DADVGLNGRIHYELD 621
            D D+G NGR+ Y ++
Sbjct: 2126 DKDIGANGRLMYSIE 2140



 Score =  222 bits (542), Expect = 1e-55
 Identities = 221/793 (27%), Positives = 354/793 (44%), Gaps = 88/793 (11%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            FRI+  +G L+   +LDRE +      ++    AS  S + S TA +   I D NDN P 
Sbjct: 2464 FRINSSTGDLIVNKTLDREAMGNGLGSLRFEVYASDSSSQGSLTAIL--TITDINDNAPA 2521

Query: 150  FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209
            F     TVS  E+  +     +A + ATDAD   N+ I + I+ GN    FSID ++GD+
Sbjct: 2522 FQNTPLTVSCSENRPI--GLTVATLTATDADATTNAIITFVIVSGNEGEAFSIDKVTGDI 2579

Query: 210  SLVKTLDYEQ-VRSYRLVIRAQDGGSPSRSNTTQLL-INIRDVNDNAPRFYTSLFQESVS 267
            ++ K LDY++  R Y L I A +  +     +  ++ INI DV+D    F   L++  + 
Sbjct: 2580 TISKPLDYDKGPRVYTLNISAMNNHTDLMLQSFGVVTINITDVDDLPANFSQKLYEAHID 2639

Query: 268  ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
            +N P+G  I +V A D D  +NA + Y++      G +     I+  SG V   G L   
Sbjct: 2640 KNSPLGSLITQVHAKDMDS-LNAPVEYSIYPDSDPGGL---FAINKTSGEVTVDGNL--- 2692

Query: 328  TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387
                Y L+V A       +S T                 +   Y+V + E E    PV+ 
Sbjct: 2693 RNGVYSLIVNA-------KSTTQPLAFTLVKVTVSTLSNLT--YDVSILEGEA-NVPVMD 2742

Query: 388  LTATDADEDNRLHYEITGGNTR---GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444
            L   ++      H+ ++GGN        S+ S NG  L   + PLD +   +++L +S T
Sbjct: 2743 LKPAES------HFNVSGGNFTFFDSSGSMFSINGTNLRVGSTPLDRETAAQHILDISLT 2796

Query: 445  DSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504
            + GG                     +    TA +  D P+ T +    A+D D+G N ++
Sbjct: 2797 E-GG-------------------TIKGFVKTAEI--DTPVATVI----ASDKDIGANGRL 2830

Query: 505  TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT 564
             YS+      E+ AH   Q + +  +GAI+   +L     + Y++ V   DGG P+L   
Sbjct: 2831 MYSI------ESGAHGHFQ-IKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSR 2883

Query: 565  TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624
              V   V+DV   +P  +   Y  +++E       V  +   ++   ++G      D   
Sbjct: 2884 AMV---VIDV---KPKPRNLTYDVSVLEGE-ANVQVMDLKPAESHFNVSGGNFTFFD--- 2933

Query: 625  REEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP 684
               GS      + +   +  LDRE+ A H L     +GGT      V V + + DIND  
Sbjct: 2934 -SSGSMFSINGTNLRVGSTPLDRETAAQHILDISLTEGGT--IKGFVKVTVNVLDINDET 2990

Query: 685  PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD 744
            P+F+S      ++E   +GT    + A D D G N+ + YSI  G++   FS+  + G+ 
Sbjct: 2991 PLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAVGNEEGFFSINNKTGA- 3049

Query: 745  KAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801
               +     LD E+ R +Y L + A     PPL +   V I V D NDN PV++D  I  
Sbjct: 3050 ---ISVAKQLDRET-RDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQV 3105

Query: 802  NNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNV 859
            +  +      P   V A D D+    +L Y I SG   +  + + ++G+++L+  L+ N 
Sbjct: 3106 SLSETAEIDTPVATVIASDKDIGANGRLMYSIESGALGHFQIKDWSSGAISLAGMLSYNQ 3165

Query: 860  PKLATMEVSVTDG 872
                 + V+VTDG
Sbjct: 3166 RNNYIVVVNVTDG 3178



 Score =  220 bits (537), Expect = 5e-55
 Identities = 240/871 (27%), Positives = 372/871 (42%), Gaps = 113/871 (12%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND+ PV +      S+ E A   T V T+ A+D+DIG N  + Y+IE       
Sbjct: 1309 IQVGDANDNPPVIQDAVIRVSLSETAEIDTPVATVIASDKDIGANGRLMYSIE------- 1361

Query: 71   NPEDAXXXXXXXXXXVQDVFRI-DGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                               F+I D  SGA+     L   +   Y V+V  TD  SP    
Sbjct: 1362 -------------SGAHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPA--- 1405

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            L S A + +++       P+    TY VSV E  +   N  +  +K  ++    +    +
Sbjct: 1406 LKSRAMVVIDV------KPKPRNLTYDVSVLEGEA---NVQVMDLKPAESHFNVSGG-NF 1455

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
                 +  M FSI+  +  V     LD E    + L I   +GG+       ++ +N+ D
Sbjct: 1456 TFFDSSGSM-FSINGTNLRVGSTP-LDRETAAQHILDISLTEGGTIK--GFVKVTVNVLD 1511

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            +ND  P F +  F  SV+E   +G   + V A D D G N+ LTY++      GN +   
Sbjct: 1512 INDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIA----AGNEEGFF 1567

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            +I+ ++G +  + QLDRET+ +Y L V A DGG+PP ++T                    
Sbjct: 1568 SINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDA 1627

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
               V L+E     TPV T+ A+D D          G N R  +SI S    G   +    
Sbjct: 1628 VIRVSLSETAAIDTPVATVIASDKD---------IGANGRLMYSIES-GAHGHFQI---- 1673

Query: 430  DFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
              K      ++++   S  + +  +V +N+TD  +  P  ++                ++
Sbjct: 1674 --KDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGS--PALKSR--------------AMV 1715

Query: 490  VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
            V+  T         +TY +S  +  EA        V++ +TGAI+  K LDRET   Y L
Sbjct: 1716 VIDVTPKP----RNLTYDVSV-LEGEANVQ-----VMDLKTGAISVAKQLDRETRDQYTL 1765

Query: 550  TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
            TV A+DGG P L+ TT V I V D NDN PV +  +   ++ E A + T V+ V A+D D
Sbjct: 1766 TVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKD 1825

Query: 610  VGLNGRIHYELDPKDREEGSFVI-DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
            +G NGR+ Y ++      G F I D +SG I     L       + +     DGG+P   
Sbjct: 1826 IGANGRLMYSIE--SGAHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALK 1883

Query: 669  STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
            S  +V I   D+   P       LT+ +S         GE      D  P  V H+++ G
Sbjct: 1884 SRAMVVI---DVTPKP-----RNLTYDVS------VLEGEANVQVMDLKP-VVSHFNVSG 1928

Query: 729  GD---DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVT 785
            G+    ++S S+ +  G++    V    LD E+  +    +       +   V+V + V 
Sbjct: 1929 GNFTFFNSSGSMFSINGNNLR--VGSTPLDRETAAQHVLDISLTEGGTIKGFVKVTVNVL 1986

Query: 786  DVNDNAPVMK--DFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLIL 841
            D+ND  P+ +   F +  N  +    V  F  V A D D      L Y I +GN      
Sbjct: 1987 DINDETPLFQSPSFNVSVNEIERLGTV--FLTVSATDGDAGANSALTYSIAAGNEEGFFS 2044

Query: 842  LNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            +N  TG+++++ QL+       T+ V   DG
Sbjct: 2045 INNKTGAISVAKQLDRETRDQYTLTVMAQDG 2075



 Score =  218 bits (533), Expect = 2e-54
 Identities = 194/646 (30%), Positives = 294/646 (45%), Gaps = 72/646 (11%)

Query: 268  ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
            E   I   +  V A D D G N  L Y++ +    G+  +    D  SG +  +G L   
Sbjct: 484  ETAEIDTPVATVIASDKDIGANGRLMYSI-ESGALGHFQIK---DWSSGAISLAGMLSYN 539

Query: 328  TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387
             +  Y ++V  TDGG P   + A                    ++V + E E     V+ 
Sbjct: 540  QRNNYIVVVNVTDGGSPALKSRAIVVIDVTPKPRNLT------HDVSVLEGEA-NVQVMD 592

Query: 388  LTATDADEDNRLHYEITGGNTR---GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444
            L   ++      H+ ++GGN        S+ S NG  L   + PLD +   +++L +S T
Sbjct: 593  LKPAES------HFNVSGGNFTFFDSSGSMFSINGTNLRVGSTPLDRETAAQHILDISLT 646

Query: 445  DSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504
            + G       V +N+ D N+  P+F++  +  SV E   +GT  L VSATD D G N+ +
Sbjct: 647  EGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSAL 706

Query: 505  TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT 564
            TYS+       A  + +  F IN +TGAI+  K LDRET   Y LTV A+DGG P L+ T
Sbjct: 707  TYSI-------AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNST 759

Query: 565  TDVEISVVDVNDNEPVFKQQLYTANIME----------DALVGTSVSQVGATDA------ 608
            T V I V D NDN PV +  +   ++ E           AL   ++  +  T        
Sbjct: 760  TAVAIQVGDANDNPPVIQDAVIRVSLSEVVVNVTDGGSPALKSRAMVVIDVTPKPRNLTY 819

Query: 609  DVG-LNGRIHYE-LDPKDREE------GSFVIDPASG----VIRTN-----KALDRESVA 651
            DV  L G  + + +D K  E       G+F    +SG    +  TN       LDRE+ A
Sbjct: 820  DVSVLEGEANVQVMDLKPAESHFNVSGGNFTFFDSSGSMFSINGTNLRVGSTPLDRETAA 879

Query: 652  THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711
             H L     +GGT      V V + + DIND  P+F+S      ++E   +GT    + A
Sbjct: 880  QHILDISLTEGGT--IKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSA 937

Query: 712  HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA-- 769
             D D G N+ + YSI  G++   FS+  + G+    +     LD E+ R +Y L + A  
Sbjct: 938  TDGDAGANSALTYSIAVGNEEGFFSINNKTGA----ISVAKQLDRET-RDQYTLTVMAQD 992

Query: 770  -ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDK 826
               PPL +   V I V D NDN PV++D  I  +  +      P   V A D D+    +
Sbjct: 993  GGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGANGR 1052

Query: 827  LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            L Y I SG + +  + + ++G+++L+  L+ N      + V+VTDG
Sbjct: 1053 LMYSIESGAHGHFRIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDG 1098



 Score =  203 bits (496), Expect = 5e-50
 Identities = 182/605 (30%), Positives = 280/605 (46%), Gaps = 57/605 (9%)

Query: 158  SVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI-DSLSGDVSLVKTLD 216
            ++D + +  D PV A + A+D D+GAN  + Y+I  G     F I D  SG +SL   L 
Sbjct: 480  TLDRETAEIDTPV-ATVIASDKDIGANGRLMYSIESG-ALGHFQIKDWSSGAISLAGMLS 537

Query: 217  YEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSI 276
            Y Q  +Y +V+   DGGSP+  +   ++I++     N     + L  E+   NV +   +
Sbjct: 538  YNQRNNYIVVVNVTDGGSPALKSRAIVVIDVTPKPRNLTHDVSVLEGEA---NVQV-MDL 593

Query: 277  VRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLV 336
               +++    G N       T  D +G++      + R G    S  LDRET A++ L +
Sbjct: 594  KPAESHFNVSGGN------FTFFDSSGSMFSINGTNLRVG----STPLDRETAAQHILDI 643

Query: 337  TATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD-- 394
            + T+GG        T              F    + V + E E  GT  +T++ATD D  
Sbjct: 644  SLTEGGTIKGFVKVT--VNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAG 701

Query: 395  EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDT 452
             ++ L Y I  GN  G FSI   N  G I+VA+ LD +   +Y LTV A D G    + T
Sbjct: 702  ANSALTYSIAAGNEEGFFSI--NNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNST 759

Query: 453  AMVQINITDANNYAPVFENAPYTASVFE----------DAPIGTTVLVVSATDS------ 496
              V I + DAN+  PV ++A    S+ E           A     ++V+  T        
Sbjct: 760  TAVAIQVGDANDNPPVIQDAVIRVSLSEVVVNVTDGGSPALKSRAMVVIDVTPKPRNLTY 819

Query: 497  DVGI-----NAQITYSLSSE----ISNEAVAHHD---QQFVINPQTGAITTNKLLDRETM 544
            DV +     N Q+     +E    +S       D     F IN     + +  L DRET 
Sbjct: 820  DVSVLEGEANVQVMDLKPAESHFNVSGGNFTFFDSSGSMFSINGTNLRVGSTPL-DRETA 878

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
            + ++L ++  +GG  ++     V ++V+D+ND  P+F+   +  ++ E   +GT    V 
Sbjct: 879  AQHILDISLTEGG--TIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVS 936

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            ATD D G N  + Y +     EEG F I+  +G I   K LDRE+   + L  +A DGG 
Sbjct: 937  ATDGDAGANSALTYSI-AVGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGE 995

Query: 665  PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
            PP +ST  V I++ D ND+PPV +   +   +SE + I T +  + A D D G N  + Y
Sbjct: 996  PPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGANGRLMY 1055

Query: 725  SIKGG 729
            SI+ G
Sbjct: 1056 SIESG 1060



 Score =  192 bits (468), Expect = 1e-46
 Identities = 171/576 (29%), Positives = 256/576 (44%), Gaps = 56/576 (9%)

Query: 276  IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL 335
            +  V A D D G N  L Y++    + G+  +    D  SG +  +G L    +  Y ++
Sbjct: 2814 VATVIASDKDIGANGRLMYSIESGAH-GHFQIK---DSSSGAISLAGMLSYNQRNNYIVV 2869

Query: 336  VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395
            V  TDGG P   + A                    Y+V + E E     V+ L   ++  
Sbjct: 2870 VNVTDGGSPALKSRAMVVIDVKPKPRNLT------YDVSVLEGEA-NVQVMDLKPAES-- 2920

Query: 396  DNRLHYEITGGNTR---GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT 452
                H+ ++GGN        S+ S NG  L   + PLD +   +++L +S T+ G     
Sbjct: 2921 ----HFNVSGGNFTFFDSSGSMFSINGTNLRVGSTPLDRETAAQHILDISLTEGGTIKGF 2976

Query: 453  AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512
              V +N+ D N+  P+F++  +  SV E   +GT  L VSATD D G N+ +TYS+    
Sbjct: 2977 VKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI---- 3032

Query: 513  SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572
               AV + +  F IN +TGAI+  K LDRET   Y LTV A+DGG P L+ TT V I V 
Sbjct: 3033 ---AVGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVG 3089

Query: 573  DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632
            D NDN PV +  +   ++ E A + T V+ V A+D D+G NGR+ Y ++      G F I
Sbjct: 3090 DANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGANGRLMYSIE--SGALGHFQI 3147

Query: 633  -DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691
             D +SG I     L       + +     DGG+P   S  IV I   D+   P     D 
Sbjct: 3148 KDWSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAIVVI---DVTPKPRNLTHD- 3203

Query: 692  LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS---NSFSLETRQGSDKAEL 748
                      +    GE      D  P A  H+++ GG+ +   +S S+ +  G++    
Sbjct: 3204 ----------VSVLEGEANVQVMDLKP-AESHFNVSGGNFTFFDSSGSMFSINGTNLR-- 3250

Query: 749  VTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMK--DFQIIFNNYKD 806
            V    LD E+  +    +       +   V+V + V D+ND  P+ +   F +  N  + 
Sbjct: 3251 VGSTPLDRETAAQHILDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIER 3310

Query: 807  CFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLI 840
               V  F  V A D D      L Y I +GN   L+
Sbjct: 3311 LGTV--FLTVSATDGDAGANSALTYSIAAGNEEGLV 3344



 Score =  190 bits (464), Expect = 4e-46
 Identities = 138/443 (31%), Positives = 210/443 (47%), Gaps = 31/443 (6%)

Query: 292  LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
            LTY ++  +   NV +   +D ++G +  + QLDRET+ +Y L V A DGG+PP ++T  
Sbjct: 1726 LTYDVSVLEGEANVQV---MDLKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTA 1782

Query: 352  XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTR 409
                                 V L+E     TPV T+ A+D D   + RL Y I  G   
Sbjct: 1783 VAIQVGDANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESG-AH 1841

Query: 410  GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAP 467
            G F I   +  G I++A  L + Q   Y++ V+ TD G  +    AMV I++T      P
Sbjct: 1842 GHFQIKDSSS-GAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVT------P 1894

Query: 468  VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA-QITYSLSSEISNEAVAHHDQQFVI 526
               N  Y  SV E       V+ +    S   ++    T+  SS             F I
Sbjct: 1895 KPRNLTYDVSVLE-GEANVQVMDLKPVVSHFNVSGGNFTFFNSS----------GSMFSI 1943

Query: 527  NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586
            N     + +  L DRET + ++L ++  +GG  ++     V ++V+D+ND  P+F+   +
Sbjct: 1944 NGNNLRVGSTPL-DRETAAQHVLDISLTEGG--TIKGFVKVTVNVLDINDETPLFQSPSF 2000

Query: 587  TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646
              ++ E   +GT    V ATD D G N  + Y +     EEG F I+  +G I   K LD
Sbjct: 2001 NVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-AAGNEEGFFSINNKTGAISVAKQLD 2059

Query: 647  RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706
            RE+   + L  +A DGG PP +ST  V I++ D ND+PPV +   +   +SE + I T +
Sbjct: 2060 RETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSETAEIDTPV 2119

Query: 707  GEIRAHDPDEGPNAVVHYSIKGG 729
              + A D D G N  + YSI+ G
Sbjct: 2120 ATVIASDKDIGANGRLMYSIESG 2142



 Score =  168 bits (409), Expect = 2e-39
 Identities = 166/599 (27%), Positives = 261/599 (43%), Gaps = 70/599 (11%)

Query: 36   ASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRI-DG 94
            A   T V T+ A+D+DIG N  + Y+IE                          F+I D 
Sbjct: 2808 AEIDTPVATVIASDKDIGANGRLMYSIE--------------------SGAHGHFQIKDS 2847

Query: 95   RSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKT 154
             SGA+     L   +   Y V+V  TD  SP    L S A + +++       P+    T
Sbjct: 2848 SSGAISLAGMLSYNQRNNYIVVVNVTDGGSPA---LKSRAMVVIDV------KPKPRNLT 2898

Query: 155  YTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT 214
            Y VSV E  +   N  +  +K  ++    +    +     +  M FSI+  +  V     
Sbjct: 2899 YDVSVLEGEA---NVQVMDLKPAESHFNVSGG-NFTFFDSSGSM-FSINGTNLRVGST-P 2952

Query: 215  LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY 274
            LD E    + L I   +GG  +     ++ +N+ D+ND  P F +  F  SV+E   +G 
Sbjct: 2953 LDRETAAQHILDISLTEGG--TIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGT 3010

Query: 275  SIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQL 334
              + V A D D G N+ LTY++      GN +   +I+ ++G +  + QLDRET+ +Y L
Sbjct: 3011 VFLTVSATDGDAGANSALTYSIA----VGNEEGFFSINNKTGAISVAKQLDRETRDQYTL 3066

Query: 335  LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394
             V A DGG+PP ++T                      +V L+E     TPV T+ A+D D
Sbjct: 3067 TVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKD 3126

Query: 395  --EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS-- 450
               + RL Y I  G   G F I   +  G I++A  L + Q   Y++ V+ TD G  +  
Sbjct: 3127 IGANGRLMYSIESG-ALGHFQIKDWSS-GAISLAGMLSYNQRNNYIVVVNVTDGGSPALK 3184

Query: 451  DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN-AQITYSLS 509
              A+V I++T      P   N  +  SV E       V+ +   +S   ++    T+  S
Sbjct: 3185 SRAIVVIDVT------PKPRNLTHDVSVLE-GEANVQVMDLKPAESHFNVSGGNFTFFDS 3237

Query: 510  SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569
            S             F IN  T     +  LDRET + ++L ++  +GG  ++     V +
Sbjct: 3238 S----------GSMFSIN-GTNLRVGSTPLDRETAAQHILDISLTEGG--TIKGFVKVTV 3284

Query: 570  SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG 628
            +V+D+ND  P+F+   +  ++ E   +GT    V ATD D G N  + Y +     EEG
Sbjct: 3285 NVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-AAGNEEG 3342



 Score =  149 bits (361), Expect = 1e-33
 Identities = 127/421 (30%), Positives = 193/421 (45%), Gaps = 32/421 (7%)

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASV 478
            G I+VA+ LD +   +Y LTV A D G    + T  V I + DAN+  PV ++A    S+
Sbjct: 1747 GAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSL 1806

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             E A I T V  V A+D D+G N ++ YS+      E+ AH   Q + +  +GAI+   +
Sbjct: 1807 SETAAIDTPVATVIASDKDIGANGRLMYSI------ESGAHGHFQ-IKDSSSGAISLAGM 1859

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            L     + Y++ V   DGG P+L     V   V+DV    P  +   Y  +++E      
Sbjct: 1860 LSYNQRNNYIVVVNVTDGGSPALKSRAMV---VIDVT---PKPRNLTYDVSVLEGE-ANV 1912

Query: 599  SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
             V  +    +   ++G      +      GS      + +   +  LDRE+ A H L   
Sbjct: 1913 QVMDLKPVVSHFNVSGGNFTFFN----SSGSMFSINGNNLRVGSTPLDRETAAQHVLDIS 1968

Query: 659  AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
              +GGT      V V + + DIND  P+F+S      ++E   +GT    + A D D G 
Sbjct: 1969 LTEGGTI--KGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGA 2026

Query: 719  NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLW 775
            N+ + YSI  G++   FS+  + G+    +     LD E+ R +Y L + A     PPL 
Sbjct: 2027 NSALTYSIAAGNEEGFFSINNKTGA----ISVAKQLDRET-RDQYTLTVMAQDGGEPPLN 2081

Query: 776  NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILS 833
            +   V I V D NDN PV++D  I  +  +      P   V A D D+    +L Y I S
Sbjct: 2082 STTAVAIQVGDANDNPPVIQDAVIRVSLSETAEIDTPVATVIASDKDIGANGRLMYSIES 2141

Query: 834  G 834
            G
Sbjct: 2142 G 2142



 Score =  131 bits (316), Expect = 3e-28
 Identities = 120/403 (29%), Positives = 182/403 (45%), Gaps = 44/403 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +NVLD ND +P+F+   +  SV E    GT  LT+ ATD D G N+ + Y+I +      
Sbjct: 2981 VNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAV------ 3034

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                            +  F I+ ++GA+     LDRE   +YT+ V A D   P    L
Sbjct: 3035 -------------GNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEP---PL 3078

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +ST  + + + D NDN P   +    VS+ E   + D PV A + A+D D+GAN  + Y+
Sbjct: 3079 NSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEI-DTPV-ATVIASDKDIGANGRLMYS 3136

Query: 191  IIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            I  G     F I D  SG +SL   L Y Q  +Y +V+   DGGSP+  +   ++I++  
Sbjct: 3137 IESG-ALGHFQIKDWSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAIVVIDVTP 3195

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
               N     + L  E+   NV +   +   +++    G N       T  D +G++    
Sbjct: 3196 KPRNLTHDVSVLEGEA---NVQV-MDLKPAESHFNVSGGN------FTFFDSSGSMFSIN 3245

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
              + R G    S  LDRET A++ L ++ T+GG        T              F   
Sbjct: 3246 GTNLRVG----STPLDRETAAQHILDISLTEGGTIKGFVKVT--VNVLDINDETPLFQSP 3299

Query: 370  QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRG 410
             + V + E E  GT  +T++ATD D   ++ L Y I  GN  G
Sbjct: 3300 SFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAAGNEEG 3342



 Score =  126 bits (304), Expect = 9e-27
 Identities = 125/427 (29%), Positives = 184/427 (43%), Gaps = 53/427 (12%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND+ PV +      S+ E A+  T V T+ A+D+DIG N  + Y+IE       
Sbjct: 1785 IQVGDANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIE------- 1837

Query: 71   NPEDAXXXXXXXXXXVQDVFRI-DGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                               F+I D  SGA+     L   +   Y V+V  TD  SP    
Sbjct: 1838 -------------SGAHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPA--- 1881

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE---DISVTD-NPVIAKIKATDADVGANS 185
            L S A + +++       P+    TY VSV E   ++ V D  PV++    +    G N 
Sbjct: 1882 LKSRAMVVIDVT------PKPRNLTYDVSVLEGEANVQVMDLKPVVSHFNVS----GGN- 1930

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
               +     +  M FSI+  +  V     LD E    + L I   +GG+       ++ +
Sbjct: 1931 ---FTFFNSSGSM-FSINGNNLRVGSTP-LDRETAAQHVLDISLTEGGTIK--GFVKVTV 1983

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
            N+ D+ND  P F +  F  SV+E   +G   + V A D D G N+ LTY++      GN 
Sbjct: 1984 NVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIA----AGNE 2039

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
            +   +I+ ++G +  + QLDRET+ +Y L V A DGG+PP ++T                
Sbjct: 2040 EGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPV 2099

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLI 423
                   V L+E     TPV T+ A+D D   + RL Y I  G   G F I   +     
Sbjct: 2100 IQDAVIRVSLSETAEIDTPVATVIASDKDIGANGRLMYSIESG-AHGHFQIKDSSKCRRY 2158

Query: 424  TVAQPLD 430
            TV    D
Sbjct: 2159 TVFNSFD 2165



 Score =  103 bits (246), Expect = 9e-20
 Identities = 86/281 (30%), Positives = 129/281 (45%), Gaps = 16/281 (5%)

Query: 466  APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525
            AP    +P+ + V  +  + TT   +    +  G N  ITYSL      E +AH    F 
Sbjct: 2416 APPTFGSPFWSDVLPE--VNTTAGTIITRLTATGGNGTITYSL------EDIAH--PWFR 2465

Query: 526  INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD-TTDVEISVVDVNDNEPVFKQQ 584
            IN  TG +  NK LDRE M   L ++        S S  +    +++ D+NDN P F+  
Sbjct: 2466 INSSTGDLIVNKTLDREAMGNGLGSLRFEVYASDSSSQGSLTAILTITDINDNAPAFQNT 2525

Query: 585  LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA 644
              T +  E+  +G +V+ + ATDAD   N  I + +     E  +F ID  +G I  +K 
Sbjct: 2526 PLTVSCSENRPIGLTVATLTATDADATTNAIITFVI-VSGNEGEAFSIDKVTGDITISKP 2584

Query: 645  LDRE-SVATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
            LD +     + L   A++  T     S  +V I I D++D P  F       +I +NSP+
Sbjct: 2585 LDYDKGPRVYTLNISAMNNHTDLMLQSFGVVTINITDVDDLPANFSQKLYEAHIDKNSPL 2644

Query: 703  GTTIGEIRAHDPDEGPNAVVHYSI-KGGDDSNSFSLETRQG 742
            G+ I ++ A D D   NA V YSI    D    F++    G
Sbjct: 2645 GSLITQVHAKDMD-SLNAPVEYSIYPDSDPGGLFAINKTSG 2684



 Score = 95.5 bits (227), Expect = 2e-17
 Identities = 92/318 (28%), Positives = 144/318 (45%), Gaps = 42/318 (13%)

Query: 33  REGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRI 92
           RE A   T V T+ A+D+DIG N  + Y+IE                          F+I
Sbjct: 483 RETAEIDTPVATVIASDKDIGANGRLMYSIE--------------------SGALGHFQI 522

Query: 93  -DGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151
            D  SGA+     L   +   Y V+V  TD  SP    L S A + +++       P+  
Sbjct: 523 KDWSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPA---LKSRAIVVIDVT------PKPR 573

Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSL 211
             T+ VSV E  +   N  +  +K  ++    +    +     +  M FSI+  +  V  
Sbjct: 574 NLTHDVSVLEGEA---NVQVMDLKPAESHFNVSGG-NFTFFDSSGSM-FSINGTNLRVGS 628

Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271
              LD E    + L I   +GG+       ++ +N+ D+ND  P F +  F  SV+E   
Sbjct: 629 TP-LDRETAAQHILDISLTEGGTIK--GFVKVTVNVLDINDETPLFQSPSFNVSVNEIER 685

Query: 272 IGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK 331
           +G   + V A D D G N+ LTY++      GN +   +I+ ++G +  + QLDRET+ +
Sbjct: 686 LGTVFLTVSATDGDAGANSALTYSIA----AGNEEGFFSINNKTGAISVAKQLDRETRDQ 741

Query: 332 YQLLVTATDGGDPPRSAT 349
           Y L V A DGG+PP ++T
Sbjct: 742 YTLTVMAQDGGEPPLNST 759



 Score = 89.0 bits (211), Expect = 2e-15
 Identities = 85/302 (28%), Positives = 140/302 (46%), Gaps = 22/302 (7%)

Query: 579  PVFKQQLYTANIME-DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637
            P F    ++  + E +   GT ++++ AT    G NG I Y L+  D     F I+ ++G
Sbjct: 2418 PTFGSPFWSDVLPEVNTTAGTIITRLTAT----GGNGTITYSLE--DIAHPWFRINSSTG 2471

Query: 638  VIRTNKALDRESVATH--DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695
             +  NK LDRE++      L+       +  Q S   + + I DIND+ P F++  LT  
Sbjct: 2472 DLIVNKTLDREAMGNGLGSLRFEVYASDSSSQGSLTAI-LTITDINDNAPAFQNTPLTVS 2530

Query: 696  ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755
             SEN PIG T+  + A D D   NA++ + I  G++  +FS++   G    ++     LD
Sbjct: 2531 CSENRPIGLTVATLTATDADATTNAIITFVIVSGNEGEAFSIDKVTG----DITISKPLD 2586

Query: 756  YESPRKKYELVIRAASP----PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811
            Y+   + Y L I A +      L +   V I +TDV D+ P     ++   +     P+G
Sbjct: 2587 YDKGPRVYTLNISAMNNHTDLMLQSFGVVTINITDV-DDLPANFSQKLYEAHIDKNSPLG 2645

Query: 812  P-FGRVPAYDAD-VTDKLQYRILSGNN-ANLILLNETTGSMTLSPQLNTNVPKLATMEVS 868
                +V A D D +   ++Y I   ++   L  +N+T+G +T+   L   V  L     S
Sbjct: 2646 SLITQVHAKDMDSLNAPVEYSIYPDSDPGGLFAINKTSGEVTVDGNLRNGVYSLIVNAKS 2705

Query: 869  VT 870
             T
Sbjct: 2706 TT 2707



 Score = 88.6 bits (210), Expect = 2e-15
 Identities = 129/515 (25%), Positives = 206/515 (40%), Gaps = 57/515 (11%)

Query: 373 VELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
           V  +E+ P G  V TLTATDAD      + + I  GN    FSI    G   IT+++PLD
Sbjct: 279 VSCSENRPIGLTVATLTATDADATTNAIITFVIVSGNEGEAFSIDKVTGD--ITISKPLD 336

Query: 431 FKQ-ERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
           ++   R Y L +SA ++          +V INITD ++    F    Y A + +++P+  
Sbjct: 337 YENGPRVYTLNISAMNNHTDLMLQSFGVVTINITDVDDLPANFSQKLYEAHIDKNSPLPC 396

Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
                 +T +      +  Y   +  +  +    D    +N   G I T           
Sbjct: 397 FCFAWKSTPTSRCY--RHIYFPGAPPTFGSPFWSDVLPEVNTTAGTIITR---------- 444

Query: 547 YLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
             LT T  +G +  SL D        ++ +  + +  + L       D  V T +    A
Sbjct: 445 --LTATGGNGTITYSLEDIAHPWFR-INSSTGDLIVNKTLDRETAEIDTPVATVI----A 497

Query: 606 TDADVGLNGRIHYELDPKDREEGSFVI-DPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
           +D D+G NGR+ Y ++      G F I D +SG I     L       + +     DGG+
Sbjct: 498 SDKDIGANGRLMYSIE--SGALGHFQIKDWSSGAISLAGMLSYNQRNNYIVVVNVTDGGS 555

Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
           P   S  IV I   D+   P     D           +    GE      D  P A  H+
Sbjct: 556 PALKSRAIVVI---DVTPKPRNLTHD-----------VSVLEGEANVQVMDLKP-AESHF 600

Query: 725 SIKGGDDS---NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781
           ++ GG+ +   +S S+ +  G++    V    LD E+  +    +       +   V+V 
Sbjct: 601 NVSGGNFTFFDSSGSMFSINGTNLR--VGSTPLDRETAAQHILDISLTEGGTIKGFVKVT 658

Query: 782 ILVTDVNDNAPVMK--DFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNA 837
           + V D+ND  P+ +   F +  N  +    V  F  V A D D      L Y I +GN  
Sbjct: 659 VNVLDINDETPLFQSPSFNVSVNEIERLGTV--FLTVSATDGDAGANSALTYSIAAGNEE 716

Query: 838 NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
               +N  TG+++++ QL+       T+ V   DG
Sbjct: 717 GFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDG 751



 Score = 81.0 bits (191), Expect = 4e-13
 Identities = 49/140 (35%), Positives = 73/140 (52%), Gaps = 4/140 (2%)

Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194
           T  + I D NDN P F     TVS  E+  +     +A + ATDAD   N+ I + I+ G
Sbjct: 257 TAILTITDINDNAPAFQNTPLTVSCSENRPI--GLTVATLTATDADATTNAIITFVIVSG 314

Query: 195 NTQMQFSIDSLSGDVSLVKTLDYEQ-VRSYRLVIRAQDGGSPSRSNTTQLL-INIRDVND 252
           N    FSID ++GD+++ K LDYE   R Y L I A +  +     +  ++ INI DV+D
Sbjct: 315 NEGEAFSIDKVTGDITISKPLDYENGPRVYTLNISAMNNHTDLMLQSFGVVTINITDVDD 374

Query: 253 NAPRFYTSLFQESVSENVPI 272
               F   L++  + +N P+
Sbjct: 375 LPANFSQKLYEAHIDKNSPL 394



 Score = 77.8 bits (183), Expect = 4e-12
 Identities = 53/136 (38%), Positives = 72/136 (52%), Gaps = 9/136 (6%)

Query: 457 INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA 516
           + ITD N+ AP F+N P T S  E+ PIG TV  ++ATD+D   NA IT+ + S    EA
Sbjct: 260 LTITDINDNAPAFQNTPLTVSCSENRPIGLTVATLTATDADATTNAIITFVIVSGNEGEA 319

Query: 517 VAHHDQQFVINPQTGAITTNKLLDRET-MSGYLLTVTARDGGVP-SLSDTTDVEISVVDV 574
                  F I+  TG IT +K LD E     Y L ++A +      L     V I++ DV
Sbjct: 320 -------FSIDKVTGDITISKPLDYENGPRVYTLNISAMNNHTDLMLQSFGVVTINITDV 372

Query: 575 NDNEPVFKQQLYTANI 590
           +D    F Q+LY A+I
Sbjct: 373 DDLPANFSQKLYEAHI 388



 Score = 64.9 bits (151), Expect = 3e-08
 Identities = 42/136 (30%), Positives = 68/136 (50%), Gaps = 3/136 (2%)

Query: 569 ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG 628
           +++ D+NDN P F+    T +  E+  +G +V+ + ATDAD   N  I + +     E  
Sbjct: 260 LTITDINDNAPAFQNTPLTVSCSENRPIGLTVATLTATDADATTNAIITFVI-VSGNEGE 318

Query: 629 SFVIDPASGVIRTNKALDRES-VATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPV 686
           +F ID  +G I  +K LD E+    + L   A++  T     S  +V I I D++D P  
Sbjct: 319 AFSIDKVTGDITISKPLDYENGPRVYTLNISAMNNHTDLMLQSFGVVTINITDVDDLPAN 378

Query: 687 FESDCLTFYISENSPI 702
           F       +I +NSP+
Sbjct: 379 FSQKLYEAHIDKNSPL 394



 Score = 64.1 bits (149), Expect = 5e-08
 Identities = 41/119 (34%), Positives = 63/119 (52%), Gaps = 8/119 (6%)

Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734
           + I DIND+ P F++  LT   SEN PIG T+  + A D D   NA++ + I  G++  +
Sbjct: 260 LTITDINDNAPAFQNTPLTVSCSENRPIGLTVATLTATDADATTNAIITFVIVSGNEGEA 319

Query: 735 FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP----PLWNDVRVEILVTDVND 789
           FS++   G    ++     LDYE+  + Y L I A +      L +   V I +TDV+D
Sbjct: 320 FSIDKVTG----DITISKPLDYENGPRVYTLNISAMNNHTDLMLQSFGVVTINITDVDD 374



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 59/227 (25%), Positives = 101/227 (44%), Gaps = 29/227 (12%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + + D ND++P F+      S  E    G TV TL ATD D   NA + + I  V+ +  
Sbjct: 2510 LTITDINDNAPAFQNTPLTVSCSENRPIGLTVATLTATDADATTNAIITFVI--VSGNE- 2566

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSDR 129
                             + F ID  +G +     LD +K  R YT+ + A +  + +   
Sbjct: 2567 ----------------GEAFSIDKVTGDITISKPLDYDKGPRVYTLNISAMNNHTDL--M 2608

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            L S   + +NI D +D    FS+K Y   +D++  +    +I ++ A D D   N+ + Y
Sbjct: 2609 LQSFGVVTINITDVDDLPANFSQKLYEAHIDKNSPL--GSLITQVHAKDMD-SLNAPVEY 2665

Query: 190  AII-GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP 235
            +I    +    F+I+  SG+V++   L   +   Y L++ A+    P
Sbjct: 2666 SIYPDSDPGGLFAINKTSGEVTVDGNL---RNGVYSLIVNAKSTTQP 2709



 Score = 56.0 bits (129), Expect = 1e-05
 Identities = 35/104 (33%), Positives = 53/104 (50%), Gaps = 5/104 (4%)

Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295
           +R      ++ I D+NDNAP F  +    S SEN PIG ++  + A DAD   NA +T+ 
Sbjct: 251 TRKGKLTAILTITDINDNAPAFQNTPLTVSCSENRPIGLTVATLTATDADATTNAIITFV 310

Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK-YQLLVTA 338
           +     +GN     +ID  +G +  S  LD E   + Y L ++A
Sbjct: 311 IV----SGNEGEAFSIDKVTGDITISKPLDYENGPRVYTLNISA 350



 Score = 47.6 bits (108), Expect = 0.005
 Identities = 42/153 (27%), Positives = 66/153 (43%), Gaps = 22/153 (14%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + + D ND++P F+      S  E    G TV TL ATD D   NA + + I  V+ +  
Sbjct: 260 LTITDINDNAPAFQNTPLTVSCSENRPIGLTVATLTATDADATTNAIITFVI--VSGNE- 316

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSDR 129
                            + F ID  +G +     LD E   R YT+ + A +  + +   
Sbjct: 317 ----------------GEAFSIDKVTGDITISKPLDYENGPRVYTLNISAMNNHTDL--M 358

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162
           L S   + +NI D +D    FS+K Y   +D++
Sbjct: 359 LQSFGVVTINITDVDDLPANFSQKLYEAHIDKN 391



 Score = 46.4 bits (105), Expect = 0.011
 Identities = 30/104 (28%), Positives = 56/104 (53%), Gaps = 7/104 (6%)

Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDK--LQYRILSGNNAN 838
           + +TD+NDNAP  ++  +  +  ++  P+G     + A DAD T    + + I+SGN   
Sbjct: 260 LTITDINDNAPAFQNTPLTVSCSENR-PIGLTVATLTATDADATTNAIITFVIVSGNEGE 318

Query: 839 LILLNETTGSMTLSPQLN-TNVPKLATMEVSVTDGVNEIKAMMQ 881
              +++ TG +T+S  L+  N P++ T+ +S  +  N    M+Q
Sbjct: 319 AFSIDKVTGDITISKPLDYENGPRVYTLNISAMN--NHTDLMLQ 360


>UniRef50_Q7YWB9 Cluster: Cadherin-like protein cad2; n=1; Aplysia
           californica|Rep: Cadherin-like protein cad2 - Aplysia
           californica (California sea hare)
          Length = 736

 Score =  303 bits (745), Expect = 3e-80
 Identities = 243/729 (33%), Positives = 363/729 (49%), Gaps = 54/729 (7%)

Query: 86  VQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145
           V+ +F ++  SG ++ R SL   +   +   V+A D   P    L S   + + ++  ND
Sbjct: 4   VEKLFDVNAYSGEIVPRDSLIDAENQLFQFFVRAADGGEP---SLESHIPVEILVMGRND 60

Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKA-TDADVGANSAIRYAIIGGNTQMQFSIDS 204
           + P+F E      VDED  V    +IA IKA +   V      R+     N    F++DS
Sbjct: 61  SPPKFLESRRPFFVDEDEQV--GAIIATIKARSSGPVVLQHCTRFHSKCQNKPAIFTVDS 118

Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
           L G + L++ LD+E   SYRL +RAQ   SP+  +  ++ I +RDVNDN P F    +Q 
Sbjct: 119 L-GRLRLMRRLDWETTPSYRLFVRAQSRTSPALVDHMEIGIEVRDVNDNPPFFACMPYQA 177

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
           +VSE+    + I+++QA D D   N  L +T+          +  +ID +SGW+    +L
Sbjct: 178 TVSESAKSQHQIIQLQASDRDLQTNP-LKFTL-GPGMQAMASI-FSIDAKSGWIMLLTKL 234

Query: 325 DRETQAKYQLLVTATD---------GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375
           DRETQ++Y L V  +D         G  P  + T +              F    Y   +
Sbjct: 235 DRETQSQYNLTVVVSDSPSSSLRKSGQYPSLTTTTSVLITVTDCNDNPPAFEKQNYPTAV 294

Query: 376 AEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ 433
            E   PGT ++TL  TDAD   ++ + Y IT G+  GRF I S    G + V +PLD + 
Sbjct: 295 NEGALPGTVLITLDTTDADSGPNSDVTYYITEGDQLGRFEIHST---GELFVNKPLDRET 351

Query: 434 ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV----FENAPYTASVFEDAPIGTTVL 489
           + +Y L V+ATD G       V +++ D N+ APV    F       +  +  PI   V 
Sbjct: 352 KAQYRLRVAATD-GAYVTFTTVTVDVLDDNDNAPVCISRFIKWFRMKTSSKALPIAH-VR 409

Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
            +   D+   +N++++YSL+ E      A H   F+I+ +TG I T KLLDRET   + L
Sbjct: 410 GIRDADAPSTVNSRVSYSLTGE-----GADH---FLIDKETGLIRTAKLLDRETQPEFEL 461

Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ----QLYTANIMEDALVGTSVSQVGA 605
           T  ARDGG   LS TT V I + DV DN P F Q    +LY+  I EDA + T   ++ A
Sbjct: 462 TAVARDGG--GLSCTTLVLIYLKDVXDNAPTFTQGTLRKLYS--IHEDAEIHTLXIRLVA 517

Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
            D D G+N +I Y    +D    +F I P SG++    AL RE   +++L  VA +  +P
Sbjct: 518 IDTDTGINSQIRYRX-ARDXIN-TFSIHPDSGIVSLIAALGRERNPSYNLTVVAYNPISP 575

Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
                + + + + D+ND+PP F+       I E++ +GT I  I A   D G NA + YS
Sbjct: 576 TSPRKLTIMVTVLDVNDNPPEFQHSSYYATIQESANVGTPIIXITATSLDIGXNADITYS 635

Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA--ASPPLWNDVRVEIL 783
           I  G++   FS++  +G     LV    LD+E  R+ +  V+     +PPL +   V I 
Sbjct: 636 IAAGNEQGKFSIDPNKG----VLVVTEPLDHELAREYFITVLATDRGTPPLTDTAIVSIN 691

Query: 784 VTDVNDNAP 792
           +TDVNDN P
Sbjct: 692 ITDVNDNPP 700



 Score =  280 bits (686), Expect = 5e-73
 Identities = 206/648 (31%), Positives = 303/648 (46%), Gaps = 40/648 (6%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           +F +D   G L     LD E    Y + V+A  + SP    L     I + + D NDN P
Sbjct: 113 IFTVDSL-GRLRLMRRLDWETTPSYRLFVRAQSRTSPA---LVDHMEIGIEVRDVNDNPP 168

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ--FSIDSLS 206
            F+   Y  +V E  S      I +++A+D D+  N  +++ +  G   M   FSID+ S
Sbjct: 169 FFACMPYQATVSE--SAKSQHQIIQLQASDRDLQTNP-LKFTLGPGMQAMASIFSIDAKS 225

Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGS---------PSRSNTTQLLINIRDVNDNAPRF 257
           G + L+  LD E    Y L +   D  S         PS + TT +LI + D NDN P F
Sbjct: 226 GWIMLLTKLDRETQSQYNLTVVVSDSPSSSLRKSGQYPSLTTTTSVLITVTDCNDNPPAF 285

Query: 258 YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317
               +  +V+E    G  ++ +   DAD G N+++TY +T+ D  G  ++  T     G 
Sbjct: 286 EKQNYPTAVNEGALPGTVLITLDTTDADSGPNSDVTYYITEGDQLGRFEIHST-----GE 340

Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377
           ++ +  LDRET+A+Y+L V ATDG     +                       + ++ + 
Sbjct: 341 LFVNKPLDRETKAQYRLRVAATDGAYVTFTTVTVDVLDDNDNAPVCISRFIKWFRMKTSS 400

Query: 378 DEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435
              P   V  +   DA    ++R+ Y +TG      F I  + G  LI  A+ LD + + 
Sbjct: 401 KALPIAHVRGIRDADAPSTVNSRVSYSLTGEGA-DHFLIDKETG--LIRTAKLLDRETQP 457

Query: 436 RYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA--SVFEDAPIGTTVLVVSA 493
            + LT  A D GG S T +V I + D  + AP F         S+ EDA I T  + + A
Sbjct: 458 EFELTAVARDGGGLSCTTLVLIYLKDVXDNAPTFTQGTLRKLYSIHEDAEIHTLXIRLVA 517

Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553
            D+D GIN+QI Y  + +  N         F I+P +G ++    L RE    Y LTV A
Sbjct: 518 IDTDTGINSQIRYRXARDXINT--------FSIHPDSGIVSLIAALGRERNPSYNLTVVA 569

Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613
            +   P+      + ++V+DVNDN P F+   Y A I E A VGT +  + AT  D+G N
Sbjct: 570 YNPISPTSPRKLTIMVTVLDVNDNPPEFQHSSYYATIQESANVGTPIIXITATSLDIGXN 629

Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673
             I Y +     E+G F IDP  GV+   + LD E    + +  +A D GTPP + T IV
Sbjct: 630 ADITYSI-AAGNEQGKFSIDPNKGVLVVTEPLDHELAREYFITVLATDRGTPPLTDTAIV 688

Query: 674 HIKIEDINDSPPVFESDCL-TFYISENSPIGTTIGEIRAHDPDEGPNA 720
            I I D+ND+PP F  D L   ++  N   GT I ++ A D D   NA
Sbjct: 689 SINITDVNDNPPRFSQDALPPVHVKXNVHEGTXIFKVMATDXDSLANA 736



 Score =  235 bits (576), Expect = 1e-59
 Identities = 184/616 (29%), Positives = 295/616 (47%), Gaps = 59/616 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V D ND+ P F    Y+A+V E A S   ++ L+A+D+D+  N  +++        TL
Sbjct: 158 IEVRDVNDNPPFFACMPYQATVSESAKSQHQIIQLQASDRDLQTN-PLKF--------TL 208

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR- 129
            P             +  +F ID +SG ++    LDRE  ++Y + V  +D  S    + 
Sbjct: 209 GP---------GMQAMASIFSIDAKSGWIMLLTKLDRETQSQYNLTVVVSDSPSSSLRKS 259

Query: 130 -----LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184
                L++T ++ + + D NDN P F ++ Y  +V+E        V+  +  TDAD G N
Sbjct: 260 GQYPSLTTTTSVLITVTDCNDNPPAFEKQNYPTAVNE--GALPGTVLITLDTTDADSGPN 317

Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
           S + Y I  G+   +F I S +G++ + K LD E    YRL + A DG   + +  T   
Sbjct: 318 SDVTYYITEGDQLGRFEIHS-TGELFVNKPLDRETKAQYRLRVAATDGAYVTFTTVT--- 373

Query: 245 INIRDVNDNAP----RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
           +++ D NDNAP    RF      ++ S+ +PI + +  ++  DA   VN+ ++Y++    
Sbjct: 374 VDVLDDNDNAPVCISRFIKWFRMKTSSKALPIAH-VRGIRDADAPSTVNSRVSYSL---- 428

Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
            TG       ID  +G + T+  LDRETQ +++L   A DGG    S T           
Sbjct: 429 -TGEGADHFLIDKETGLIRTAKLLDRETQPEFELTAVARDGGG--LSCTTLVLIYLKDVX 485

Query: 361 XXXXXFMPGQYE--VELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITS 416
                F  G       + ED    T  + L A D D   ++++ Y     +    FSI  
Sbjct: 486 DNAPTFTQGTLRKLYSIHEDAEIHTLXIRLVAIDTDTGINSQIRYR-XARDXINTFSIHP 544

Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATD--SGGRSDTAMVQINITDANNYAPVFENAPY 474
            +  G++++   L  ++   Y LTV A +  S        + + + D N+  P F+++ Y
Sbjct: 545 DS--GIVSLIAALGRERNPSYNLTVVAYNPISPTSPRKLTIMVTVLDVNDNPPEFQHSSY 602

Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
            A++ E A +GT ++ ++AT  D+G NA ITYS+       A  +   +F I+P  G + 
Sbjct: 603 YATIQESANVGTPIIXITATSLDIGXNADITYSI-------AAGNEQGKFSIDPNKGVLV 655

Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ-LYTANIMED 593
             + LD E    Y +TV A D G P L+DT  V I++ DVNDN P F Q  L   ++  +
Sbjct: 656 VTEPLDHELAREYFITVLATDRGTPPLTDTAIVSINITDVNDNPPRFSQDALPPVHVKXN 715

Query: 594 ALVGTSVSQVGATDAD 609
              GT + +V ATD D
Sbjct: 716 VHEGTXIFKVMATDXD 731



 Score =  206 bits (503), Expect = 7e-51
 Identities = 164/500 (32%), Positives = 225/500 (45%), Gaps = 44/500 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V DCND+ P FE Q Y  +V EGA  GT ++TL  TD D G N++V Y I     D L
Sbjct: 273 ITVTDCNDNPPAFEKQNYPTAVNEGALPGTVLITLDTTDADSGPNSDVTYYI--TEGDQL 330

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                              F I   +G L     LDRE  A+Y + V ATD A       
Sbjct: 331 GR-----------------FEIHS-TGELFVNKPLDRETKAQYRLRVAATDGA------Y 366

Query: 131 SSTATIHVNIIDDNDNYPQ-FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            +  T+ V+++DDNDN P   S       +           +  I+  DA    NS + Y
Sbjct: 367 VTFTTVTVDVLDDNDNAPVCISRFIKWFRMKTSSKALPIAHVRGIRDADAPSTVNSRVSY 426

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
           ++ G      F ID  +G +   K LD E    + L   A+DGG    S TT +LI ++D
Sbjct: 427 SLTGEGAD-HFLIDKETGLIRTAKLLDRETQPEFELTAVARDGG--GLSCTTLVLIYLKD 483

Query: 250 VNDNAPRFYTSLFQE--SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
           V DNAP F     ++  S+ E+  I    +R+ A D D G+N+++ Y    +D       
Sbjct: 484 VXDNAPTFTQGTLRKLYSIHEDAEIHTLXIRLVAIDTDTGINSQIRYRXA-RDXINT--- 539

Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
             +I P SG V     L RE    Y L V A +   P      T              F 
Sbjct: 540 -FSIHPDSGIVSLIAALGRERNPSYNLTVVAYNPISPTSPRKLTIMVTVLDVNDNPPEFQ 598

Query: 368 PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITV 425
              Y   + E    GTP++ +TAT  D   +  + Y I  GN +G+FSI     +G++ V
Sbjct: 599 HSSYYATIQESANVGTPIIXITATSLDIGXNADITYSIAAGNEQGKFSI--DPNKGVLVV 656

Query: 426 AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVF-ENAPYTASVFEDA 482
            +PLD +  R Y +TV ATD G    +DTA+V INITD N+  P F ++A     V  + 
Sbjct: 657 TEPLDHELAREYFITVLATDRGTPPLTDTAIVSINITDVNDNPPRFSQDALPPVHVKXNV 716

Query: 483 PIGTTVLVVSATDSDVGINA 502
             GT +  V ATD D   NA
Sbjct: 717 HEGTXIFKVMATDXDSLANA 736



 Score =  127 bits (306), Expect = 5e-27
 Identities = 126/448 (28%), Positives = 185/448 (41%), Gaps = 30/448 (6%)

Query: 441 VSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498
           V A D G  S      V+I +   N+  P F  +     V ED  +G  +  + A  S  
Sbjct: 35  VRAADGGEPSLESHIPVEILVMGRNDSPPKFLESRRPFFVDEDEQVGAIIATIKARSSGP 94

Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558
            +    T    S+  N+        F ++   G +   + LD ET   Y L V A+    
Sbjct: 95  VVLQHCT-RFHSKCQNKPAI-----FTVD-SLGRLRLMRRLDWETTPSYRLFVRAQSRTS 147

Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618
           P+L D  ++ I V DVNDN P F    Y A + E A     + Q+ A+D D+  N  + +
Sbjct: 148 PALVDHMEIGIEVRDVNDNPPFFACMPYQATVSESAKSQHQIIQLQASDRDLQTNP-LKF 206

Query: 619 ELDPKDREEGS-FVIDPASGVIRTNKALDRESVATHDLKAVAID---------GGTPPQS 668
            L P  +   S F ID  SG I     LDRE+ + ++L  V  D         G  P  +
Sbjct: 207 TLGPGMQAMASIFSIDAKSGWIMLLTKLDRETQSQYNLTVVVSDSPSSSLRKSGQYPSLT 266

Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
           +T  V I + D ND+PP FE       ++E +  GT +  +   D D GPN+ V Y I  
Sbjct: 267 TTTSVLITVTDCNDNPPAFEKQNYPTAVNEGALPGTVLITLDTTDADSGPNSDVTYYITE 326

Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVN 788
           GD    F + +       EL     LD E+ + +Y L + A          V + V D N
Sbjct: 327 GDQLGRFEIHST-----GELFVNKPLDRET-KAQYRLRVAATDGAYVTFTTVTVDVLDDN 380

Query: 789 DNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY-DADVTDKLQYRI---LSGNNANLILLNE 844
           DNAPV     I +   K      P   V    DAD    +  R+   L+G  A+  L+++
Sbjct: 381 DNAPVCISRFIKWFRMKTSSKALPIAHVRGIRDADAPSTVNSRVSYSLTGEGADHFLIDK 440

Query: 845 TTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            TG +  +  L+        +     DG
Sbjct: 441 ETGLIRTAKLLDRETQPEFELTAVARDG 468



 Score = 75.8 bits (178), Expect = 2e-11
 Identities = 89/367 (24%), Positives = 157/367 (42%), Gaps = 22/367 (5%)

Query: 521 DQQFVINPQTGAITT-NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP 579
           ++ F +N  +G I   + L+D E    +   V A DGG PSL     VEI V+  ND+ P
Sbjct: 5   EKLFDVNAYSGEIVPRDSLIDAENQL-FQFFVRAADGGEPSLESHIPVEILVMGRNDSPP 63

Query: 580 VFKQQLYTANIMEDALVGTSVSQVGA-TDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638
            F +      + ED  VG  ++ + A +   V L     +    +++    F +D + G 
Sbjct: 64  KFLESRRPFFVDEDEQVGAIIATIKARSSGPVVLQHCTRFHSKCQNKP-AIFTVD-SLGR 121

Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698
           +R  + LD E+  ++ L   A    +P     + + I++ D+ND+PP F        +SE
Sbjct: 122 LRLMRRLDWETTPSYRLFVRAQSRTSPALVDHMEIGIEVRDVNDNPPFFACMPYQATVSE 181

Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS--FSLETRQGSDKAELVTMVDLDY 756
           ++     I +++A D D   N +  +++  G  + +  FS++ + G     L+T +D + 
Sbjct: 182 SAKSQHQIIQLQASDRDLQTNPL-KFTLGPGMQAMASIFSIDAKSGW--IMLLTKLDRET 238

Query: 757 ESPRKKYELVIRAAS---------PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC 807
           +S      +V  + S         P L     V I VTD NDN P  +         +  
Sbjct: 239 QSQYNLTVVVSDSPSSSLRKSGQYPSLTTTTSVLITVTDCNDNPPAFEKQNYPTAVNEGA 298

Query: 808 FPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATM 865
            P      +   DAD      + Y I  G+      ++ +TG + ++  L+        +
Sbjct: 299 LPGTVLITLDTTDADSGPNSDVTYYITEGDQLGRFEIH-STGELFVNKPLDRETKAQYRL 357

Query: 866 EVSVTDG 872
            V+ TDG
Sbjct: 358 RVAATDG 364


>UniRef50_Q7PTV6 Cluster: ENSANGP00000002131; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000002131 - Anopheles gambiae
           str. PEST
          Length = 603

 Score =  303 bits (745), Expect = 3e-80
 Identities = 217/617 (35%), Positives = 312/617 (50%), Gaps = 36/617 (5%)

Query: 142 DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFS 201
           D NDN P F+ + Y VSV E  S  + PVI ++K TD D G N+ +   I+GGN   +F 
Sbjct: 1   DINDNAPVFNREIYEVSVPET-SPPNTPVI-RLKVTDRDEGKNAKVFLEIVGGNEGGEFR 58

Query: 202 IDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS--RSNTTQLLINIRDVNDNAPRFYT 259
           ++  +G +     LD E    Y L + A D G+P   + ++ ++ IN++D NDN P F T
Sbjct: 59  VNPETGMLYTAVPLDAELKAFYTLTVSAIDQGNPGTRKQSSAKVKINVQDTNDNDPIFET 118

Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319
           +     V EN P G S+ +V A D D G NA ++Y++ + +     D+P  ID  SG V 
Sbjct: 119 ANLTIYVDENEPAGTSVTKVTARDKDLGENAYISYSIANLN-----DVPFDIDHFSGTVR 173

Query: 320 TSGQLDRET-QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX-XFMPGQYEVELAE 377
           TS  LD E+ + +Y L V A+D G P R  T                 F        +  
Sbjct: 174 TSKLLDYESMRREYVLRVRASDWGLPYRRQTEMQLVIKLRDVNDNRPQFERIDCLGRIPR 233

Query: 378 DEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG-------RGLITVAQPLD 430
             P GT + TL+A D D  + + Y +  G   G F++ S  G          + +   LD
Sbjct: 234 YTPIGTEIFTLSALDFDYGSVVTYRLLSGFEDGCFNLDSVTGIISVGCDLNDLKIIGYLD 293

Query: 431 FKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
            +++  Y+L ++  D G   +S + ++ + I D N+  P FE +  +  V E+A  GT +
Sbjct: 294 RERQDEYLLNITVYDLGKPQKSISKILPLTILDENDNVPKFEKSLASFRVTENAINGTII 353

Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
             V ATD+D+G NA+ITYSL ++          + F ++P+TG +T    LDRE    Y 
Sbjct: 354 FRVKATDADLGQNAKITYSLVTD---------TKDFRVDPETGVLTVVAPLDRERQEVYE 404

Query: 549 LTVTARDGG----VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
           L + A DGG     P+L     V ++V D+NDN P F  Q  T  I ED   GT V+ V 
Sbjct: 405 LKIRATDGGGDQNTPALYSDALVRVTVDDINDNAPEFAVQDLTVRIREDVPRGTVVTVVS 464

Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
           A D D G +  I Y        EGSF ID  SG IRT + LD E    H L   AID GT
Sbjct: 465 AIDLDSGTSSEIVYSFGENGDGEGSFRIDKQSGTIRTARMLDFEERQVHSLIVKAIDRGT 524

Query: 665 PPQSSTVIVHIKIEDINDS--PPVFESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAV 721
           P  SS   V +++ D+N++   P FE   LT  I+EN P G  + ++ A D D  GP++ 
Sbjct: 525 PSLSSETSVIVEVIDVNENRFAPQFEDYVLTGAIAENKPPGAQVMQVLAKDADLPGPDSR 584

Query: 722 VHYSIKGGDDSNSFSLE 738
           V YSIKGGD    F+++
Sbjct: 585 VTYSIKGGDGLGIFTID 601



 Score =  285 bits (700), Expect = 9e-75
 Identities = 221/637 (34%), Positives = 312/637 (48%), Gaps = 54/637 (8%)

Query: 15  DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
           D ND++PVF  + YE SV E +   T V+ LK TD+D GKNA+V   +E+V  +      
Sbjct: 1   DINDNAPVFNREIYEVSVPETSPPNTPVIRLKVTDRDEGKNAKV--FLEIVGGNEGGE-- 56

Query: 75  AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134
                          FR++  +G L T   LD E  A YT+ V A DQ +P   R  S+A
Sbjct: 57  ---------------FRVNPETGMLYTAVPLDAELKAFYTLTVSAIDQGNP-GTRKQSSA 100

Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194
            + +N+ D NDN P F     T+ VDE+     +  + K+ A D D+G N+ I Y+I   
Sbjct: 101 KVKINVQDTNDNDPIFETANLTIYVDENEPAGTS--VTKVTARDKDLGENAYISYSIANL 158

Query: 195 NTQMQFSIDSLSGDVSLVKTLDYEQV-RSYRLVIRAQDGGSPSRSNT-TQLLINIRDVND 252
           N  + F ID  SG V   K LDYE + R Y L +RA D G P R  T  QL+I +RDVND
Sbjct: 159 N-DVPFDIDHFSGTVRTSKLLDYESMRREYVLRVRASDWGLPYRRQTEMQLVIKLRDVND 217

Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD--KDYTGNVDLP-- 308
           N P+F        +    PIG  I  + A D D G  + +TY +    +D   N+D    
Sbjct: 218 NRPQFERIDCLGRIPRYTPIGTEIFTLSALDFDYG--SVVTYRLLSGFEDGCFNLDSVTG 275

Query: 309 -ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
            I++      +   G LDRE Q +Y L +T  D G P +S +                F 
Sbjct: 276 IISVGCDLNDLKIIGYLDRERQDEYLLNITVYDLGKPQKSISKILPLTILDENDNVPKFE 335

Query: 368 PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITV 425
                  + E+   GT +  + ATDAD  ++ ++ Y +   +T+  F +  +   G++TV
Sbjct: 336 KSLASFRVTENAINGTIIFRVKATDADLGQNAKITYSLV-TDTKD-FRVDPET--GVLTV 391

Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDT------AMVQINITDANNYAPVFENAPYTASVF 479
             PLD +++  Y L + ATD GG  +T      A+V++ + D N+ AP F     T  + 
Sbjct: 392 VAPLDRERQEVYELKIRATDGGGDQNTPALYSDALVRVTVDDINDNAPEFAVQDLTVRIR 451

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           ED P GT V VVSA D D G +++I YS       E        F I+ Q+G I T ++L
Sbjct: 452 EDVPRGTVVTVVSAIDLDSGTSSEIVYSFGENGDGEG------SFRIDKQSGTIRTARML 505

Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE--PVFKQQLYTANIMEDALVG 597
           D E    + L V A D G PSLS  T V + V+DVN+N   P F+  + T  I E+   G
Sbjct: 506 DFEERQVHSLIVKAIDRGTPSLSSETSVIVEVIDVNENRFAPQFEDYVLTGAIAENKPPG 565

Query: 598 TSVSQVGATDADV-GLNGRIHYELDPKDREEGSFVID 633
             V QV A DAD+ G + R+ Y +   D   G F ID
Sbjct: 566 AQVMQVLAKDADLPGPDSRVTYSIKGGD-GLGIFTID 601



 Score =  250 bits (613), Expect = 3e-64
 Identities = 194/620 (31%), Positives = 305/620 (49%), Gaps = 44/620 (7%)

Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
           D+NDNAP F   +++ SV E  P    ++R++  D DEG NA++   +      GN    
Sbjct: 1   DINDNAPVFNREIYEVSVPETSPPNTPVIRLKVTDRDEGKNAKVFLEIVG----GNEGGE 56

Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXXXXF 366
             ++P +G +YT+  LD E +A Y L V+A D G+P   + ++A               F
Sbjct: 57  FRVNPETGMLYTAVPLDAELKAFYTLTVSAIDQGNPGTRKQSSAKVKINVQDTNDNDPIF 116

Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLIT 424
                 + + E+EP GT V  +TA D D  E+  + Y I   N    F I   +  G + 
Sbjct: 117 ETANLTIYVDENEPAGTSVTKVTARDKDLGENAYISYSIANLNDVP-FDI--DHFSGTVR 173

Query: 425 VAQPLDFKQERR-YVLTVSATDSG--GRSDTAM-VQINITDANNYAPVFENAPYTASVFE 480
            ++ LD++  RR YVL V A+D G   R  T M + I + D N+  P FE       +  
Sbjct: 174 TSKLLDYESMRREYVLRVRASDWGLPYRRQTEMQLVIKLRDVNDNRPQFERIDCLGRIPR 233

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP--QTGAITTNKL 538
             PIGT +  +SA D D G  + +TY L S   +          +I+       +     
Sbjct: 234 YTPIGTEIFTLSALDFDYG--SVVTYRLLSGFEDGCFNLDSVTGIISVGCDLNDLKIIGY 291

Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
           LDRE    YLL +T  D G P  S +  + ++++D NDN P F++ L +  + E+A+ GT
Sbjct: 292 LDRERQDEYLLNITVYDLGKPQKSISKILPLTILDENDNVPKFEKSLASFRVTENAINGT 351

Query: 599 SVSQVGATDADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
            + +V ATDAD+G N +I Y L  D KD     F +DP +GV+     LDRE    ++LK
Sbjct: 352 IIFRVKATDADLGQNAKITYSLVTDTKD-----FRVDPETGVLTVVAPLDRERQEVYELK 406

Query: 657 AVAIDGG----TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
             A DGG    TP   S  +V + ++DIND+ P F    LT  I E+ P GT +  + A 
Sbjct: 407 IRATDGGGDQNTPALYSDALVRVTVDDINDNAPEFAVQDLTVRIREDVPRGTVVTVVSAI 466

Query: 713 DPDEGPNAVVHYSI-KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA-- 769
           D D G ++ + YS  + GD   SF ++ + G+ +   +    LD+E  R+ + L+++A  
Sbjct: 467 DLDSGTSSEIVYSFGENGDGEGSFRIDKQSGTIRTARM----LDFEE-RQVHSLIVKAID 521

Query: 770 -ASPPLWNDVRVEILVTDVNDN--APVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--- 823
             +P L ++  V + V DVN+N  AP  +D+ +     ++  P     +V A DAD+   
Sbjct: 522 RGTPSLSSETSVIVEVIDVNENRFAPQFEDYVLTGAIAENKPPGAQVMQVLAKDADLPGP 581

Query: 824 TDKLQYRILSGNNANLILLN 843
             ++ Y I  G+   +  ++
Sbjct: 582 DSRVTYSIKGGDGLGIFTID 601



 Score =  194 bits (474), Expect = 2e-47
 Identities = 163/521 (31%), Positives = 243/521 (46%), Gaps = 56/521 (10%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +INV D ND+ P+FE       V E   +GT+V  + A D+D+G+NA + Y+I       
Sbjct: 103 KINVQDTNDNDPIFETANLTIYVDENEPAGTSVTKVTARDKDLGENAYISYSI------- 155

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSD 128
            N  D               F ID  SG + T   LD E + R Y + V+A+D   P   
Sbjct: 156 ANLNDV-------------PFDIDHFSGTVRTSKLLDYESMRREYVLRVRASDWGLPY-- 200

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
           R  +   + + + D NDN PQF        +     +     I  + A D D G  S + 
Sbjct: 201 RRQTEMQLVIKLRDVNDNRPQFERIDCLGRIPRYTPI--GTEIFTLSALDFDYG--SVVT 256

Query: 189 YAIIGGNTQMQFSIDSLSG---------DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239
           Y ++ G     F++DS++G         D+ ++  LD E+   Y L I   D G P +S 
Sbjct: 257 YRLLSGFEDGCFNLDSVTGIISVGCDLNDLKIIGYLDRERQDEYLLNITVYDLGKPQKSI 316

Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
           +  L + I D NDN P+F  SL    V+EN   G  I RV+A DAD G NA++TY++   
Sbjct: 317 SKILPLTILDENDNVPKFEKSLASFRVTENAINGTIIFRVKATDADLGQNAKITYSLV-- 374

Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG----DPPRSATATXXXX 355
             T   D    +DP +G +     LDRE Q  Y+L + ATDGG     P   + A     
Sbjct: 375 --TDTKD--FRVDPETGVLTVVAPLDRERQEVYELKIRATDGGGDQNTPALYSDALVRVT 430

Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI-TGGNTRGRF 412
                     F      V + ED P GT V  ++A D D    + + Y     G+  G F
Sbjct: 431 VDDINDNAPEFAVQDLTVRIREDVPRGTVVTVVSAIDLDSGTSSEIVYSFGENGDGEGSF 490

Query: 413 SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS----DTAMVQINITDANNYAPV 468
            I  Q+  G I  A+ LDF++ + + L V A D G  S     + +V++   + N +AP 
Sbjct: 491 RIDKQS--GTIRTARMLDFEERQVHSLIVKAIDRGTPSLSSETSVIVEVIDVNENRFAPQ 548

Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDV-GINAQITYSL 508
           FE+   T ++ E+ P G  V+ V A D+D+ G ++++TYS+
Sbjct: 549 FEDYVLTGAIAENKPPGAQVMQVLAKDADLPGPDSRVTYSI 589



 Score =  155 bits (377), Expect = 1e-35
 Identities = 120/416 (28%), Positives = 195/416 (46%), Gaps = 31/416 (7%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I + D ND+ P FE       +      GT + TL A D D G  + V Y +     D  
Sbjct: 210 IKLRDVNDNRPQFERIDCLGRIPRYTPIGTEIFTLSALDFDYG--SVVTYRLLSGFEDGC 267

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
              D+          + D+ +I G          LDRE+   Y + +   D   P   + 
Sbjct: 268 FNLDSVTGIISVGCDLNDL-KIIGY---------LDRERQDEYLLNITVYDLGKP---QK 314

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           S +  + + I+D+NDN P+F +   +  V E+    +  +I ++KATDAD+G N+ I Y+
Sbjct: 315 SISKILPLTILDENDNVPKFEKSLASFRVTEN--AINGTIIFRVKATDADLGQNAKITYS 372

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG----SPSRSNTTQLLIN 246
           ++       F +D  +G +++V  LD E+   Y L IRA DGG    +P+  +   + + 
Sbjct: 373 LV--TDTKDFRVDPETGVLTVVAPLDRERQEVYELKIRATDGGGDQNTPALYSDALVRVT 430

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
           + D+NDNAP F        + E+VP G  +  V A D D G ++E+ Y+  +    G+ +
Sbjct: 431 VDDINDNAPEFAVQDLTVRIREDVPRGTVVTVVSAIDLDSGTSSEIVYSFGEN---GDGE 487

Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
               ID +SG + T+  LD E +  + L+V A D G P  S+  +               
Sbjct: 488 GSFRIDKQSGTIRTARMLDFEERQVHSLIVKAIDRGTPSLSSETSVIVEVIDVNENRFAP 547

Query: 367 MPGQYEVE--LAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQ 417
               Y +   +AE++PPG  V+ + A DAD    D+R+ Y I GG+  G F+I ++
Sbjct: 548 QFEDYVLTGAIAENKPPGAQVMQVLAKDADLPGPDSRVTYSIKGGDGLGIFTIDNE 603



 Score =  148 bits (358), Expect = 3e-33
 Identities = 95/291 (32%), Positives = 151/291 (51%), Gaps = 14/291 (4%)

Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632
           D+NDN PVF +++Y  ++ E +   T V ++  TD D G N ++  E+     E G F +
Sbjct: 1   DINDNAPVFNREIYEVSVPETSPPNTPVIRLKVTDRDEGKNAKVFLEI-VGGNEGGEFRV 59

Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPP--QSSTVIVHIKIEDINDSPPVFESD 690
           +P +G++ T   LD E  A + L   AID G P   + S+  V I ++D ND+ P+FE+ 
Sbjct: 60  NPETGMLYTAVPLDAELKAFYTLTVSAIDQGNPGTRKQSSAKVKINVQDTNDNDPIFETA 119

Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750
            LT Y+ EN P GT++ ++ A D D G NA + YSI   +D   F ++   G+ +   + 
Sbjct: 120 NLTIYVDENEPAGTSVTKVTARDKDLGENAYISYSIANLNDV-PFDIDHFSGTVRTSKL- 177

Query: 751 MVDLDYESPRKKYELVIRAASPPL----WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKD 806
              LDYES R++Y L +RA+   L      ++++ I + DVNDN P  +    +      
Sbjct: 178 ---LDYESMRREYVLRVRASDWGLPYRRQTEMQLVIKLRDVNDNRPQFERIDCL-GRIPR 233

Query: 807 CFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
             P+G     + A D D    + YR+LSG       L+  TG +++   LN
Sbjct: 234 YTPIGTEIFTLSALDFDYGSVVTYRLLSGFEDGCFNLDSVTGIISVGCDLN 284


>UniRef50_Q4SYV0 Cluster: Chromosome undetermined SCAF11948, whole
            genome shotgun sequence; n=2; Euteleostomi|Rep:
            Chromosome undetermined SCAF11948, whole genome shotgun
            sequence - Tetraodon nigroviridis (Green puffer)
          Length = 3085

 Score =  296 bits (726), Expect = 6e-78
 Identities = 266/910 (29%), Positives = 406/910 (44%), Gaps = 74/910 (8%)

Query: 2    SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
            S+P     +  +   N   PVF+   Y  SV E  +  T VL + AT     K   + YT
Sbjct: 2211 SIPLSSTTEFPITVVNKAMPVFDKPFYSISVNEDVAVHTPVLGINATSP---KGQSIIYT 2267

Query: 62   IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121
            I  V  D                 +Q  F I   +G +     LD E  ARY + V+ATD
Sbjct: 2268 I--VDGDP---------------SLQ--FDIGFDTGVIAVIHPLDHETAARYNLTVRATD 2308

Query: 122  QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181
              +     +     + V + D NDN P F +  Y V + E + +   P +  + ATD D 
Sbjct: 2309 CLTGAHAEVD----VDVAVKDVNDNQPLFKKMAYQVVLSETVMI-GTPAL-HVSATDKDS 2362

Query: 182  GANSAIRYAIIGG-NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240
              N+ I Y I    N    F IDS SG +   + LD+E V+ +  V+ A D G P  S+ 
Sbjct: 2363 DKNNVIHYQIFSDHNNTDYFHIDSSSGLILTARMLDHELVQKFDFVVIATDNGFPPLSSE 2422

Query: 241  TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
              + + + D+NDN P F   L++  V E  P G+ +  VQA DAD     +L Y++    
Sbjct: 2423 VSVTVMVSDINDNPPVFNQLLYEAYVDELAPRGHFVTCVQASDADSSDYEKLEYSIL--- 2479

Query: 301  YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
             +GN  L   +D  +G V  S +  +  +  Y L ++ +DG     ++TA          
Sbjct: 2480 -SGNEKLVFMLDKMTGIVTLSSRYKQRMEPAYSLNISVSDG---VFTSTAQVHIKVSQGN 2535

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQN 418
                 F    YE ++ E+   GT VV + ATD+D     R+ Y       R RFSI   +
Sbjct: 2536 LYAPVFEQNVYEAQVKENSVVGTRVVQVKATDSDPGVFGRVTYSFVNDVGRERFSI---D 2592

Query: 419  GRGLITVAQPLDFKQ-ERRYVL-TVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA 476
              G IT A+ LD +    +YV+ +V+A D+GG    A VQ+++ D N+ AP F    Y A
Sbjct: 2593 ANGQITTAEKLDREDPSNQYVVVSVAAQDAGGHVSYATVQVSLVDENDNAPHFWATEYRA 2652

Query: 477  SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
            SV      G  +  V A+D D G NA+ITYS+ S+ S+  V        I+P  G I T 
Sbjct: 2653 SVRSSVAEGFLLTQVQASDPDAGTNARITYSIYSD-SHVPVT---DILEIDPDNGWIVTK 2708

Query: 537  KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
                    S     V A DGG P+      V + V+    + P F QQ Y  ++ ED  V
Sbjct: 2709 GAFGHLMNSVLYFFVKAEDGGHPARHSLVSVYVHVLSPAASIPSFLQQHYEFSVAEDTSV 2768

Query: 597  GTSVSQVGATD----ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652
            GT+V  +        A +     +      K  ++G FV++  +G+IR NK LD E +  
Sbjct: 2769 GTAVGMLRLKTPPGYASLSAVFSLVNGAMEKYNQDGVFVVEKDTGLIRLNKPLDHELIKE 2828

Query: 653  HDLKAVA-IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711
            +  KA A +        ++V V +K+ D ND+ P F ++     + E  P+ T I ++RA
Sbjct: 2829 YYFKATATVQQAKLDSVASVDVQVKVLDRNDNKPEFVTESFEAAVMEGVPLATRILQVRA 2888

Query: 712  HDPDEGPNAVVHYSIKGGDDS--------NSFSLETRQGSDKAELVTMVDLDYESPRKKY 763
             D D G N  V YS+ G   S        N+FS++++ G     + T+ +LD+E+     
Sbjct: 2889 LDADSGANGQVRYSLGGLIQSESQQETLFNTFSIDSQSG----WISTLTNLDHETSSSYV 2944

Query: 764  ELVIRAASPPLWN---DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAY 819
              V+ +    + +      V ++VTDVNDN P   + Q  F + ++  P G     +   
Sbjct: 2945 FTVVASDFGEITSFSATATVTVVVTDVNDNPPRFLE-QRYFGSVQEGSPPGEVVAALDTR 3003

Query: 820  DAD--VTDK-LQYRILSGNNANLILLNETTGSMTL--SPQLNTNVPKLATMEVSVTDGVN 874
            D D   T++ + Y I  GN      L    G   L    +L+     L  + VS +DG+ 
Sbjct: 3004 DNDGSATNRHVSYHITGGNYRGSFALGLVQGEWKLYVKFRLDREERSLYRINVSASDGLF 3063

Query: 875  EIKAMMQLSV 884
                ++ +SV
Sbjct: 3064 VCHTLVHVSV 3073



 Score =  278 bits (682), Expect = 1e-72
 Identities = 239/795 (30%), Positives = 368/795 (46%), Gaps = 61/795 (7%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ V D ND+ PVF    Y A+V+  A  GT +  + A DQD G N  V Y +       
Sbjct: 2117 KVQVEDVNDNVPVFVGLPYYAAVQVDAEPGTAIFRVMAIDQDKGINGHVSYYL------- 2169

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDRE-KVARYTVLVKATDQASPVSD 128
               +D               F I+  +G L  + + + +     Y +++ A D     S 
Sbjct: 2170 --LDD------------HGHFEINKLTGILSLKKAFESDLSNVEYQMVIYARDHG---SI 2212

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             LSST    + ++  N   P F +  Y++SV+ED++V   PV+  I AT        +I 
Sbjct: 2213 PLSSTTEFPITVV--NKAMPVFDKPFYSISVNEDVAV-HTPVLG-INATSP---KGQSII 2265

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            Y I+ G+  +QF I   +G ++++  LD+E    Y L +RA D  + + +    + + ++
Sbjct: 2266 YTIVDGDPSLQFDIGFDTGVIAVIHPLDHETAARYNLTVRATDCLTGAHAE-VDVDVAVK 2324

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            DVNDN P F    +Q  +SE V IG   + V A D D   N  + Y +   D+  N D  
Sbjct: 2325 DVNDNQPLFKKMAYQVVLSETVMIGTPALHVSATDKDSDKNNVIHYQIF-SDH-NNTDY- 2381

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
              ID  SG + T+  LD E   K+  +V ATD G PP S+  +              F  
Sbjct: 2382 FHIDSSSGLILTARMLDHELVQKFDFVVIATDNGFPPLSSEVSVTVMVSDINDNPPVFNQ 2441

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVA 426
              YE  + E  P G  V  + A+DAD  +  +L Y I  GN +  F +      G++T++
Sbjct: 2442 LLYEAYVDELAPRGHFVTCVQASDADSSDYEKLEYSILSGNEKLVFMLDKMT--GIVTLS 2499

Query: 427  QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
                 + E  Y L +S +D G  + TA V I ++  N YAPVFE   Y A V E++ +GT
Sbjct: 2500 SRYKQRMEPAYSLNISVSD-GVFTSTAQVHIKVSQGNLYAPVFEQNVYEAQVKENSVVGT 2558

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
             V+ V ATDSD G+  ++TYS  +++  E       +F I+   G ITT + LDRE  S 
Sbjct: 2559 RVVQVKATDSDPGVFGRVTYSFVNDVGRE-------RFSID-ANGQITTAEKLDREDPSN 2610

Query: 547  --YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
               +++V A+D G   +S  T V++S+VD NDN P F    Y A++      G  ++QV 
Sbjct: 2611 QYVVVSVAAQDAG-GHVSYAT-VQVSLVDENDNAPHFWATEYRASVRSSVAEGFLLTQVQ 2668

Query: 605  ATDADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
            A+D D G N RI Y +  D          IDP +G I T  A      +       A DG
Sbjct: 2669 ASDPDAGTNARITYSIYSDSHVPVTDILEIDPDNGWIVTKGAFGHLMNSVLYFFVKAEDG 2728

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
            G P + S V V++ +     S P F      F ++E++ +GT +G +R   P    +   
Sbjct: 2729 GHPARHSLVSVYVHVLSPAASIPSFLQQHYEFSVAEDTSVGTAVGMLRLKTPPGYASLSA 2788

Query: 723  HYSIKGG--DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY---ELVIRAASPPLWND 777
             +S+  G  +  N   +   +  D   +     LD+E  ++ Y      ++ A       
Sbjct: 2789 VFSLVNGAMEKYNQDGVFVVE-KDTGLIRLNKPLDHELIKEYYFKATATVQQAKLDSVAS 2847

Query: 778  VRVEILVTDVNDNAP 792
            V V++ V D NDN P
Sbjct: 2848 VDVQVKVLDRNDNKP 2862



 Score =  272 bits (666), Expect = 1e-70
 Identities = 248/872 (28%), Positives = 381/872 (43%), Gaps = 70/872 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-------LKATDQDIGKNAEVEYTIE 63
            I + D ND+ PVF+  +Y  S+ E A+  + VL        +KATD D  +NA + Y I 
Sbjct: 1803 IQLKDENDNPPVFQQLRYHGSISEAAAVNSVVLNPDDSPLVIKATDADRNENALLVYQIV 1862

Query: 64   LVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQA 123
                     ED               F +D  +G++ T ASLD E +A +   V   D  
Sbjct: 1863 ---------EDVAKMF----------FAVDSGTGSIRTIASLDHETLAIFHFHVFVRDSG 1903

Query: 124  SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY-TVSVDEDISVTDNPVIAKIKATDADVG 182
             P        A + + ++D ND+ PQFS+ +Y TV +    +  +   + ++KATD D  
Sbjct: 1904 RPQLTA-DGPAEVTIQVMDTNDSPPQFSQSSYETVLLRPTYAGVE---VLQVKATDPDED 1959

Query: 183  ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
             +  + Y++  G  +  F+I+ LSG + +VK  ++   R +   +R  DG     S+T  
Sbjct: 1960 VSRNLTYSLTNGVLE-HFAIEPLSGTI-VVKQSNFSNER-FLFGVRVSDG---QFSSTAL 2013

Query: 243  LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA-DEGVNAELTYTMTDKDY 301
            + + +R+  D+   F  SL+  ++ EN      I +V   +A     N  + YT+     
Sbjct: 2014 VNVLVREALDSGLSFSQSLYSSTIQENES---GITQVAVVNALGNQANEPIVYTLL---- 2066

Query: 302  TGNVDLPITIDPRSGWVYTSG-QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
              N  +   I P SG + T+G   DRE Q  Y+L+V A    D  R A            
Sbjct: 2067 --NGGMYFKIRPTSGVIQTTGVAFDREEQESYELVVEARREDDHLRVARVLVKVQVEDVN 2124

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420
                 F+   Y   +  D  PGT +  + A D D+    H      +  G F I    G 
Sbjct: 2125 DNVPVFVGLPYYAAVQVDAEPGTAIFRVMAIDQDKGINGHVSYYLLDDHGHFEINKLTGI 2184

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
              +  A   D      Y + + A D G    ++  +  IT  N   PVF+   Y+ SV E
Sbjct: 2185 LSLKKAFESDLSNVE-YQMVIYARDHGSIPLSSTTEFPITVVNKAMPVFDKPFYSISVNE 2243

Query: 481  DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
            D  + T VL ++AT         I Y++              QF I   TG I     LD
Sbjct: 2244 DVAVHTPVLGINATSPK---GQSIIYTIVD-------GDPSLQFDIGFDTGVIAVIHPLD 2293

Query: 541  RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
             ET + Y LTV A D    + ++  DV+++V DVNDN+P+FK+  Y   + E  ++GT  
Sbjct: 2294 HETAARYNLTVRATDCLTGAHAEV-DVDVAVKDVNDNQPLFKKMAYQVVLSETVMIGTPA 2352

Query: 601  SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
              V ATD D   N  IHY++         F ID +SG+I T + LD E V   D   +A 
Sbjct: 2353 LHVSATDKDSDKNNVIHYQIFSDHNNTDYFHIDSSSGLILTARMLDHELVQKFDFVVIAT 2412

Query: 661  DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
            D G PP SS V V + + DIND+PPVF       Y+ E +P G  +  ++A D D     
Sbjct: 2413 DNGFPPLSSEVSVTVMVSDINDNPPVFNQLLYEAYVDELAPRGHFVTCVQASDADSSDYE 2472

Query: 721  VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRV 780
             + YSI  G++   F L+   G     +VT+     +     Y L I  +     +  +V
Sbjct: 2473 KLEYSILSGNEKLVFMLDKMTG-----IVTLSSRYKQRMEPAYSLNISVSDGVFTSTAQV 2527

Query: 781  EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDAD--VTDKLQYRILSGNNA 837
             I V+  N  APV +   +     K+   VG    +V A D+D  V  ++ Y  ++    
Sbjct: 2528 HIKVSQGNLYAPVFEQ-NVYEAQVKENSVVGTRVVQVKATDSDPGVFGRVTYSFVNDVGR 2586

Query: 838  NLILLNETTGSMTLSPQLNTNVPKLATMEVSV 869
                + +  G +T + +L+   P    + VSV
Sbjct: 2587 ERFSI-DANGQITTAEKLDREDPSNQYVVVSV 2617



 Score =  270 bits (661), Expect = 5e-70
 Identities = 248/903 (27%), Positives = 403/903 (44%), Gaps = 84/903 (9%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            Q+ + D ND++P F    YE  V E    GT+VLT+ A D D G+N  + Y+I  + A  
Sbjct: 445  QVAIQDANDNTPTFHQSSYEILVNESVPVGTSVLTVSAQDGDDGENGYITYSISSLGA-- 502

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS-----LDREKVARYTVLVKATDQAS 124
              P                 F     S   + RAS       RE     T+ VK  +   
Sbjct: 503  -LPFQINQFSGVITTTEPLDFDFSSDSFVFIVRASDWGSPYRRESEVYVTIHVKNVNDNQ 561

Query: 125  PVSDRLSSTATIHVNIIDDND-------NYPQFSEKTYTVSVDEDISV----TDNPVIAK 173
            P+ ++ +    I  ++  D         +  + +   Y +     + +     D+ V++ 
Sbjct: 562  PLFEKTACHGVISRDLPADQVITTVSAIDIDELALVKYKIVSGNTLGLFNLNPDSGVLSL 621

Query: 174  IKATDADVGANS-AIRYAIIGGNT---QMQFSIDSLSGDVSLVKTLDYEQVR-SYRL--- 225
             ++    V AN+ +++     G      M  +I  + G  S  K ++ ++   + RL   
Sbjct: 622  QRSLVPAVSANAFSLKITATDGENLSEPMYVNISVVEGK-SFSKNINCKETMVAQRLAEK 680

Query: 226  VIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE-SVSENVPIGYSIVRVQAYDA 284
            +++   G +  +S   +  I+I  +N   P+F  +   + +V E++ +G S+ +V AYD 
Sbjct: 681  LLKKSKGSAAPKSE--EGFIDIFSINRQTPQFSKAFPTDIAVREDLGVGSSVFQVSAYDG 738

Query: 285  DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP 344
            D G N ++ Y+++D    GN D   T+D  +G +     LDRE +  Y L +T  D G P
Sbjct: 739  DTGFNGQILYSISD----GNPDDCFTMDTDTGLISVLLPLDREKKDHYLLNLTIYDLGRP 794

Query: 345  PRSATATXXXXXXXXXXXXXXFMP-GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEI 403
            P+SA                 F+  G Y V L E+   GT V+ + ATD D         
Sbjct: 795  PKSAWHLLTVFIEDANDNAPQFLQEGGYTVVLPENTAIGTDVIQVGATDRDAGPNGEVAY 854

Query: 404  TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG----RSDTAMVQINI 459
            +       F I S +G  ++ VA  LD +    + L V A D       R     +++ +
Sbjct: 855  SLLTATANFGINSTSG--VVYVAGQLDRELVSVFYLKVEARDKAEQGSQRFSVTTLKVVL 912

Query: 460  TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAH 519
             D N+  PVF  + Y     ED P+GT +  +   D D+G   Q+ YSL+++        
Sbjct: 913  EDVNDCPPVFIPSVYKTRALEDLPVGTVLAWLETQDPDLGPGGQVQYSLAND-------- 964

Query: 520  HDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDN- 577
            ++  F ++  +GAI   K LD ET   Y L+V A+D G P +L   T VE+ VVDVN+N 
Sbjct: 965  YNGWFEVDRTSGAIRLMKELDYETQQFYNLSVKAKDRGKPVALLSVTSVEVEVVDVNENL 1024

Query: 578  -EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE-GSFVIDPA 635
              P F      A + E+A +GT++ QV A D DVG +G I Y +  +D    G F I+  
Sbjct: 1025 NAPYFSHFALKATVKENARIGTTLLQVAAQDDDVGRDGEIQYSI--RDGSGLGRFAINEE 1082

Query: 636  SGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695
            +GVI T   LDRE+  ++ L   A D G  PQ +T+ V +++ED+ND+ P+         
Sbjct: 1083 TGVIYTTDTLDRETKDSYWLTVYATDRGVVPQFATIAVFVQVEDVNDNAPLTSEAMYDSS 1142

Query: 696  ISENSPIGTTIGEIRAHDPDEGPNAV--VHYSIKGGDDSNSFSLETRQG-----SDKAEL 748
            + ENSP G ++ +I+A DPDE P     + + I  G+  N F++ +  G     S K + 
Sbjct: 1143 VQENSPEGVSVVQIQAQDPDETPLTAEKLSFHIVSGNPQNLFAINSHTGLITTTSRKLDR 1202

Query: 749  VTMVDLDYESP----------RKKY------ELVIRAASP-PLWNDVRVEILVTDVNDNA 791
                + + E+           R  +      ++++  + P P  + V V + V D NDN 
Sbjct: 1203 EQQTEHNLEASVCVRDAGVWYRASHWSVWPLQVMVSDSGPSPKHSVVWVTVRVLDDNDNK 1262

Query: 792  PVM--KDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTG 847
            P+   K +Q+     +      P  RV AYD D      L Y I  GN      ++  T 
Sbjct: 1263 PIFPEKVYQVKLAERERRKKAEPIYRVFAYDGDQGPNSDLSYSIADGNEDAKFFIDPKTA 1322

Query: 848  SMT 850
             ++
Sbjct: 1323 VLS 1325



 Score =  268 bits (657), Expect = 1e-69
 Identities = 251/883 (28%), Positives = 406/883 (45%), Gaps = 91/883 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D NDH P+F    YE SV E ++ G+ V+ + A D+D G+NA+V+Y+IE       
Sbjct: 1600 IEVKDVNDHVPIFTRSTYEGSVCESSAVGSAVVQVSALDKDKGENADVQYSIE------- 1652

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                             + F I+   G +     L+   +  Y + V+ATD+ SP    L
Sbjct: 1653 ------------SGNKGNTFHIEPILGIITISHDLNLSSIGHYVLTVRATDKGSP---PL 1697

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S+T  +H+++   ++  P+F ++ Y   + E+++V  +  I  + A      + + + Y 
Sbjct: 1698 STTTMVHISVTLSDNAAPKFPQEEYLAVITENVAVGTS--IITVSAV-----SQTTLTYD 1750

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I  G+    F I+  SG ++  K LDYE+  SY L+++A +    + SN T  +I ++D 
Sbjct: 1751 IKQGDADGVFQINQYSGVITTRKALDYEKTASYSLIVQAVNMAGMA-SNAT-AIIQLKDE 1808

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVR-------VQAYDADEGVNAELTYTMTDKDYTG 303
            NDN P F    +  S+SE   +   ++        ++A DAD   NA L Y + +     
Sbjct: 1809 NDNPPVFQQLRYHGSISEAAAVNSVVLNPDDSPLVIKATDADRNENALLVYQIVE----D 1864

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA--TATXXXXXXXXXX 361
               +   +D  +G + T   LD ET A +   V   D G P  +A   A           
Sbjct: 1865 VAKMFFAVDSGTGSIRTIASLDHETLAIFHFHVFVRDSGRPQLTADGPAEVTIQVMDTND 1924

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNG 419
                F    YE  L      G  V+ + ATD DED    L Y +T G     F+I   + 
Sbjct: 1925 SPPQFSQSSYETVLLRPTYAGVEVLQVKATDPDEDVSRNLTYSLTNG-VLEHFAIEPLS- 1982

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479
             G I V Q  +F  E R++  V  +D G  S TA+V + + +A +    F  + Y++++ 
Sbjct: 1983 -GTIVVKQS-NFSNE-RFLFGVRVSD-GQFSSTALVNVLVREALDSGLSFSQSLYSSTIQ 2038

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKL 538
            E+    T V VV+A  +    N  I Y+L          +    F I P +G I TT   
Sbjct: 2039 ENESGITQVAVVNALGNQA--NEPIVYTL---------LNGGMYFKIRPTSGVIQTTGVA 2087

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
             DRE    Y L V AR            V++ V DVNDN PVF    Y A +  DA  GT
Sbjct: 2088 FDREEQESYELVVEARREDDHLRVARVLVKVQVEDVNDNVPVFVGLPYYAAVQVDAEPGT 2147

Query: 599  SVSQVGATDADVGLNGRI-HYELDPKDREEGSFVIDPASGVIRTNKALDRE-SVATHDLK 656
            ++ +V A D D G+NG + +Y LD    + G F I+  +G++   KA + + S   + + 
Sbjct: 2148 AIFRVMAIDQDKGINGHVSYYLLD----DHGHFEINKLTGILSLKKAFESDLSNVEYQMV 2203

Query: 657  AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
              A D G+ P SST    I +  +N + PVF+    +  ++E+  + T +  I A  P +
Sbjct: 2204 IYARDHGSIPLSSTTEFPITV--VNKAMPVFDKPFYSISVNEDVAVHTPVLGINATSP-K 2260

Query: 717  GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--PPL 774
            G + +  Y+I  GD S  F +    G D   +  +  LD+E+   +Y L +RA       
Sbjct: 2261 GQSII--YTIVDGDPSLQFDI----GFDTGVIAVIHPLDHET-AARYNLTVRATDCLTGA 2313

Query: 775  WNDVRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPVG-PFGRVPA--YDADVTDKLQY 829
              +V V++ V DVNDN P+ K   +Q++ +   +   +G P   V A   D+D  + + Y
Sbjct: 2314 HAEVDVDVAVKDVNDNQPLFKKMAYQVVLS---ETVMIGTPALHVSATDKDSDKNNVIHY 2370

Query: 830  RILSG-NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            +I S  NN +   ++ ++G +  +  L+  + +     V  TD
Sbjct: 2371 QIFSDHNNTDYFHIDSSSGLILTARMLDHELVQKFDFVVIATD 2413



 Score =  262 bits (643), Expect = 7e-68
 Identities = 228/799 (28%), Positives = 344/799 (43%), Gaps = 53/799 (6%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V D ND+ P+F+   Y+  + E    GT  L + ATD+D  KN  + Y I    +D  
Sbjct: 2321 VAVKDVNDNQPLFKKMAYQVVLSETVMIGTPALHVSATDKDSDKNNVIHYQI---FSDHN 2377

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N                D F ID  SG +LT   LD E V ++  +V ATD   P    L
Sbjct: 2378 NT---------------DYFHIDSSSGLILTARMLDHELVQKFDFVVIATDNGFPP---L 2419

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            SS  ++ V + D NDN P F++  Y   VDE         +  ++A+DAD      + Y+
Sbjct: 2420 SSEVSVTVMVSDINDNPPVFNQLLYEAYVDE--LAPRGHFVTCVQASDADSSDYEKLEYS 2477

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I+ GN ++ F +D ++G V+L          +Y L I   DG   S   T Q+ I +   
Sbjct: 2478 ILSGNEKLVFMLDKMTGIVTLSSRYKQRMEPAYSLNISVSDGVFTS---TAQVHIKVSQG 2534

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            N  AP F  ++++  V EN  +G  +V+V+A D+D GV   +TY+  +    G     I 
Sbjct: 2535 NLYAPVFEQNVYEAQVKENSVVGTRVVQVKATDSDPGVFGRVTYSFVND--VGRERFSID 2592

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
             +   G + T+ +LDRE  +   ++V+          + AT              F   +
Sbjct: 2593 AN---GQITTAEKLDREDPSNQYVVVSVAAQDAGGHVSYATVQVSLVDENDNAPHFWATE 2649

Query: 371  YEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQN-GRGLITVAQ 427
            Y   +      G  +  + A+D D     R+ Y I   +      I   +   G I    
Sbjct: 2650 YRASVRSSVAEGFLLTQVQASDPDAGTNARITYSIYSDSHVPVTDILEIDPDNGWIVTKG 2709

Query: 428  PLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
                         V A D G   R     V +++       P F    Y  SV ED  +G
Sbjct: 2710 AFGHLMNSVLYFFVKAEDGGHPARHSLVSVYVHVLSPAASIPSFLQQHYEFSVAEDTSVG 2769

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
            T V ++         +    +SL +    +   + D  FV+   TG I  NK LD E + 
Sbjct: 2770 TAVGMLRLKTPPGYASLSAVFSLVNGAMEKY--NQDGVFVVEKDTGLIRLNKPLDHELIK 2827

Query: 546  GYLL--TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
             Y    T T +   + S++ + DV++ V+D NDN+P F  + + A +ME   + T + QV
Sbjct: 2828 EYYFKATATVQQAKLDSVA-SVDVQVKVLDRNDNKPEFVTESFEAAVMEGVPLATRILQV 2886

Query: 604  GATDADVGLNGRIHYEL----DPKDREE---GSFVIDPASGVIRTNKALDRESVATHDLK 656
             A DAD G NG++ Y L      + ++E    +F ID  SG I T   LD E+ +++   
Sbjct: 2887 RALDADSGANGQVRYSLGGLIQSESQQETLFNTFSIDSQSGWISTLTNLDHETSSSYVFT 2946

Query: 657  AVAIDGGTPPQ-SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
             VA D G     S+T  V + + D+ND+PP F        + E SP G  +  +   D D
Sbjct: 2947 VVASDFGEITSFSATATVTVVVTDVNDNPPRFLEQRYFGSVQEGSPPGEVVAALDTRDND 3006

Query: 716  -EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL 774
                N  V Y I GG+   SF+L   QG  K  L     LD E  R  Y + + A+    
Sbjct: 3007 GSATNRHVSYHITGGNYRGSFALGLVQGEWK--LYVKFRLDREE-RSLYRINVSASDGLF 3063

Query: 775  WNDVRVEILVTDVNDNAPV 793
                 V + V D NDN+PV
Sbjct: 3064 VCHTLVHVSVLDANDNSPV 3082



 Score =  239 bits (584), Expect = 1e-60
 Identities = 227/843 (26%), Positives = 361/843 (42%), Gaps = 79/843 (9%)

Query: 57   EVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVL 116
            E +   E+V   +L    A           + VF +D   G ++    LD E+ + Y + 
Sbjct: 1392 ESDKVSEMVGVVSLRRSAATVWFDITGGNSESVFHVDKTVGTIIIAKPLDAEQQSFYNLT 1451

Query: 117  VKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY--TVSVD--EDISVTDNPVIA 172
            V+ATD         ++ A +HV ++D NDN P FS+ TY  TV  D   D  V     + 
Sbjct: 1452 VQATDGTK------AAFAQVHVTVLDTNDNAPIFSQPTYEVTVPEDIPADTEVIQVVAVD 1505

Query: 173  KIKATDADVGANSAI-----RYAIIGGNTQMQFSIDSLSGD----------VSLVKTLDY 217
            + +         S+I     R+  I        ++ SL  +          VSL   L  
Sbjct: 1506 RDRHHQLSYSLQSSIDPSSMRFFHIHPTLGTIHTLQSLDHEACALHILTITVSLKLALFA 1565

Query: 218  EQVRSY-------RLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENV 270
                 Y       + V + +D   P R N  ++LI ++DVND+ P F  S ++ SV E+ 
Sbjct: 1566 RGFHGYMAVNNKTKTVKKVKDQEFPYRKNMARVLIEVKDVNDHVPIFTRSTYEGSVCESS 1625

Query: 271  PIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA 330
             +G ++V+V A D D+G NA++ Y++     +GN      I+P  G +  S  L+  +  
Sbjct: 1626 AVGSAVVQVSALDKDKGENADVQYSIE----SGNKGNTFHIEPILGIITISHDLNLSSIG 1681

Query: 331  KYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTA 390
             Y L V ATD G PP S T                F   +Y   + E+   GT ++T++A
Sbjct: 1682 HYVLTVRATDKGSPPLSTTTMVHISVTLSDNAAPKFPQEEYLAVITENVAVGTSIITVSA 1741

Query: 391  TDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS 450
                    L Y+I  G+  G F I   +  G+IT  + LD+++   Y L V A +  G +
Sbjct: 1742 V---SQTTLTYDIKQGDADGVFQINQYS--GVITTRKALDYEKTASYSLIVQAVNMAGMA 1796

Query: 451  DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV-------LVVSATDSDVGINAQ 503
              A   I + D N+  PVF+   Y  S+ E A + + V       LV+ ATD+D   NA 
Sbjct: 1797 SNATAIIQLKDENDNPPVFQQLRYHGSISEAAAVNSVVLNPDDSPLVIKATDADRNENAL 1856

Query: 504  ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS- 562
            + Y +  +++          F ++  TG+I T   LD ET++ +   V  RD G P L+ 
Sbjct: 1857 LVYQIVEDVAK-------MFFAVDSGTGSIRTIASLDHETLAIFHFHVFVRDSGRPQLTA 1909

Query: 563  -DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621
                +V I V+D ND+ P F Q  Y   ++     G  V QV ATD D  ++  + Y L 
Sbjct: 1910 DGPAEVTIQVMDTNDSPPQFSQSSYETVLLRPTYAGVEVLQVKATDPDEDVSRNLTYSLT 1969

Query: 622  PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681
                E   F I+P SG I     + ++S  +++     +       SST +V++ + +  
Sbjct: 1970 NGVLEH--FAIEPLSGTI-----VVKQSNFSNERFLFGVRVSDGQFSSTALVNVLVREAL 2022

Query: 682  DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741
            DS   F     +  I EN    T +  + A   ++    +V+  + GG     F +    
Sbjct: 2023 DSGLSFSQSLYSSTIQENESGITQVAVVNALG-NQANEPIVYTLLNGG---MYFKIRPTS 2078

Query: 742  GSDKAELVTMVDLDYESPRKKYELVIRAASPP---LWNDVRVEILVTDVNDNAPVMKDFQ 798
            G  +    T V  D E  ++ YELV+ A           V V++ V DVNDN PV     
Sbjct: 2079 GVIQ---TTGVAFDREE-QESYELVVEARREDDHLRVARVLVKVQVEDVNDNVPVFVGLP 2134

Query: 799  IIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
                   D  P     RV A D D  +   + Y +L  +      +N+ TG ++L     
Sbjct: 2135 YYAAVQVDAEPGTAIFRVMAIDQDKGINGHVSYYLLDDHGH--FEINKLTGILSLKKAFE 2192

Query: 857  TNV 859
            +++
Sbjct: 2193 SDL 2195



 Score =  238 bits (583), Expect = 1e-60
 Identities = 246/913 (26%), Positives = 401/913 (43%), Gaps = 105/913 (11%)

Query: 11   INVLDCNDHSPVFEMQ-QYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            I++   N  +P F      + +VRE    G++V  + A D D G N ++ Y+I    +D 
Sbjct: 698  IDIFSINRQTPQFSKAFPTDIAVREDLGVGSSVFQVSAYDGDTGFNGQILYSI----SDG 753

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             NP+D               F +D  +G +     LDREK   Y + +   D   P    
Sbjct: 754  -NPDDC--------------FTMDTDTGLISVLLPLDREKKDHYLLNLTIYDLGRPPK-- 796

Query: 130  LSSTATIHVNIIDDNDNYPQF-SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             S+   + V I D NDN PQF  E  YTV + E+ ++  +  + ++ ATD D G N  + 
Sbjct: 797  -SAWHLLTVFIEDANDNAPQFLQEGGYTVVLPENTAIGTD--VIQVGATDRDAGPNGEVA 853

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS--RSNTTQLLIN 246
            Y+++       F I+S SG V +   LD E V  + L + A+D       R + T L + 
Sbjct: 854  YSLLTATAN--FGINSTSGVVYVAGQLDRELVSVFYLKVEARDKAEQGSQRFSVTTLKVV 911

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            + DVND  P F  S+++    E++P+G  +  ++  D D G   ++ Y++ + DY G  +
Sbjct: 912  LEDVNDCPPVFIPSVYKTRALEDLPVGTVLAWLETQDPDLGPGGQVQYSLAN-DYNGWFE 970

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX- 365
                +D  SG +    +LD ETQ  Y L V A D G P    + T               
Sbjct: 971  ----VDRTSGAIRLMKELDYETQQFYNLSVKAKDRGKPVALLSVTSVEVEVVDVNENLNA 1026

Query: 366  --FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRG 421
              F     +  + E+   GT ++ + A D D   D  + Y I  G+  GRF+I  + G  
Sbjct: 1027 PYFSHFALKATVKENARIGTTLLQVAAQDDDVGRDGEIQYSIRDGSGLGRFAINEETG-- 1084

Query: 422  LITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVF 479
            +I     LD + +  Y LTV ATD G   +  T  V + + D N+ AP+   A Y +SV 
Sbjct: 1085 VIYTTDTLDRETKDSYWLTVYATDRGVVPQFATIAVFVQVEDVNDNAPLTSEAMYDSSVQ 1144

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ-FVINPQTGAITT-NK 537
            E++P G +V+ + A D D       T   + ++S   V+ + Q  F IN  TG ITT ++
Sbjct: 1145 ENSPEGVSVVQIQAQDPDE------TPLTAEKLSFHIVSGNPQNLFAINSHTGLITTTSR 1198

Query: 538  LLDRETMSGYLL--TVTARDGGV-------------PSLSDTTD--------VEISVVDV 574
             LDRE  + + L  +V  RD GV               +SD+          V + V+D 
Sbjct: 1199 KLDREQQTEHNLEASVCVRDAGVWYRASHWSVWPLQVMVSDSGPSPKHSVVWVTVRVLDD 1258

Query: 575  NDNEPVFKQQLYTANI--MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632
            NDN+P+F +++Y   +   E       + +V A D D G N  + Y +     E+  F I
Sbjct: 1259 NDNKPIFPEKVYQVKLAERERRKKAEPIYRVFAYDGDQGPNSDLSYSI-ADGNEDAKFFI 1317

Query: 633  DPASGVIRTNKALDRESVATHDLKAV----------AIDGGTPPQSSTVIVHIK-IEDIN 681
            DP + V+ + KA    +  T+++  V          A D G P +SST  +HI+ +    
Sbjct: 1318 DPKTAVLSSRKAF---AAGTYNILTVCYGFYRTSIKATDNGRPQKSSTARLHIEWVRRPP 1374

Query: 682  DSPP-VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR 740
              PP +F+     F + E+  +   +G +          A V + I GG+  + F ++  
Sbjct: 1375 AGPPLLFDQPFYNFTVMESDKVSEMVGVVSL----RRSAATVWFDITGGNSESVFHVDKT 1430

Query: 741  QGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQII 800
             G+    ++    LD E  +  Y L ++A         +V + V D NDNAP+       
Sbjct: 1431 VGT----IIIAKPLDAEQ-QSFYNLTVQATDGTKAAFAQVHVTVLDTNDNAPIFSQPTYE 1485

Query: 801  FNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSG---NNANLILLNETTGSMTLSPQLNT 857
                +D        +V A D D   +L Y + S    ++     ++ T G++     L+ 
Sbjct: 1486 VTVPEDIPADTEVIQVVAVDRDRHHQLSYSLQSSIDPSSMRFFHIHPTLGTIHTLQSLDH 1545

Query: 858  NVPKLATMEVSVT 870
                L  + ++V+
Sbjct: 1546 EACALHILTITVS 1558



 Score =  231 bits (566), Expect = 2e-58
 Identities = 243/850 (28%), Positives = 368/850 (43%), Gaps = 123/850 (14%)

Query: 15   DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
            D ND  PVF    Y+    E    GT +  L+  D D+G   +V+Y++    A+  N   
Sbjct: 914  DVNDCPPVFIPSVYKTRALEDLPVGTVLAWLETQDPDLGPGGQVQYSL----ANDYN--- 966

Query: 75   AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134
                           F +D  SGA+     LD E    Y + VKA D+  PV+  L S  
Sbjct: 967  -------------GWFEVDRTSGAIRLMKELDYETQQFYNLSVKAKDRGKPVA--LLSVT 1011

Query: 135  TIHVNIIDDNDNY--PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192
            ++ V ++D N+N   P FS      +V E+  +     + ++ A D DVG +  I+Y+I 
Sbjct: 1012 SVEVEVVDVNENLNAPYFSHFALKATVKENARI--GTTLLQVAAQDDDVGRDGEIQYSIR 1069

Query: 193  GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252
             G+   +F+I+  +G +    TLD E   SY L + A D G   +  T  + + + DVND
Sbjct: 1070 DGSGLGRFAINEETGVIYTTDTLDRETKDSYWLTVYATDRGVVPQFATIAVFVQVEDVND 1129

Query: 253  NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG-VNAELTYTMTDKDYTGNVDLPITI 311
            NAP    +++  SV EN P G S+V++QA D DE  + AE    ++    +GN      I
Sbjct: 1130 NAPLTSEAMYDSSVQENSPEGVSVVQIQAQDPDETPLTAE---KLSFHIVSGNPQNLFAI 1186

Query: 312  DPRSGWVYT-SGQLDRETQAKYQL-----------------------LVTATDGGDPPRS 347
            +  +G + T S +LDRE Q ++ L                        V  +D G  P+ 
Sbjct: 1187 NSHTGLITTTSRKLDREQQTEHNLEASVCVRDAGVWYRASHWSVWPLQVMVSDSGPSPKH 1246

Query: 348  ATATXXXXXXXXXXXXXXFMPGQYEVELAEDE--PPGTPVVTLTATDADE--DNRLHYEI 403
            +                 F    Y+V+LAE E      P+  + A D D+  ++ L Y I
Sbjct: 1247 SVVWVTVRVLDDNDNKPIFPEKVYQVKLAERERRKKAEPIYRVFAYDGDQGPNSDLSYSI 1306

Query: 404  TGGNTRGRFSITSQNG-----RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQ 456
              GN   +F I  +       +        +       Y  ++ ATD+G   +S TA + 
Sbjct: 1307 ADGNEDAKFFIDPKTAVLSSRKAFAAGTYNILTVCYGFYRTSIKATDNGRPQKSSTARLH 1366

Query: 457  INITDANNYAP--VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
            I         P  +F+   Y  +V E   +   V VVS   S   +   IT       ++
Sbjct: 1367 IEWVRRPPAGPPLLFDQPFYNFTVMESDKVSEMVGVVSLRRSAATVWFDITGG-----NS 1421

Query: 515  EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
            E+V H D+        G I   K LD E  S Y LTV A DG   + +    V ++V+D 
Sbjct: 1422 ESVFHVDKT------VGTIIIAKPLDAEQQSFYNLTVQATDGTKAAFAQ---VHVTVLDT 1472

Query: 575  NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD--VGLNGRIHYELDPKDREEGSFVI 632
            NDN P+F Q  Y   + ED    T V QV A D D    L+  +   +DP       F I
Sbjct: 1473 NDNAPIFSQPTYEVTVPEDIPADTEVIQVVAVDRDRHHQLSYSLQSSIDPSSMR--FFHI 1530

Query: 633  DPASGVIRTNKALDRESVATHDLKA----------------VAIDGGT-----------P 665
             P  G I T ++LD E+ A H L                  +A++  T           P
Sbjct: 1531 HPTLGTIHTLQSLDHEACALHILTITVSLKLALFARGFHGYMAVNNKTKTVKKVKDQEFP 1590

Query: 666  PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
             + +   V I+++D+ND  P+F        + E+S +G+ + ++ A D D+G NA V YS
Sbjct: 1591 YRKNMARVLIEVKDVNDHVPIFTRSTYEGSVCESSAVGSAVVQVSALDKDKGENADVQYS 1650

Query: 726  IKGGDDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRA---ASPPLWNDVRVE 781
            I+ G+  N+F +E   G     ++T+  DL+  S    Y L +RA    SPPL     V 
Sbjct: 1651 IESGNKGNTFHIEPILG-----IITISHDLNLSS-IGHYVLTVRATDKGSPPLSTTTMVH 1704

Query: 782  ILVTDVNDNA 791
            I VT ++DNA
Sbjct: 1705 ISVT-LSDNA 1713



 Score =  179 bits (436), Expect = 9e-43
 Identities = 141/427 (33%), Positives = 199/427 (46%), Gaps = 28/427 (6%)

Query: 457  INITDANNYAPVFENA-PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515
            I+I   N   P F  A P   +V ED  +G++V  VSA D D G N QI YS+S      
Sbjct: 698  IDIFSINRQTPQFSKAFPTDIAVREDLGVGSSVFQVSAYDGDTGFNGQILYSISD----- 752

Query: 516  AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575
               + D  F ++  TG I+    LDRE    YLL +T  D G P  S    + + + D N
Sbjct: 753  --GNPDDCFTMDTDTGLISVLLPLDREKKDHYLLNLTIYDLGRPPKSAWHLLTVFIEDAN 810

Query: 576  DNEPVFKQQL-YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634
            DN P F Q+  YT  + E+  +GT V QVGATD D G NG + Y L        +F I+ 
Sbjct: 811  DNAPQFLQEGGYTVVLPENTAIGTDVIQVGATDRDAGPNGEVAYSLLTAT---ANFGINS 867

Query: 635  ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI--EDINDSPPVFESDCL 692
             SGV+     LDRE V+   LK  A D          +  +K+  ED+ND PPVF     
Sbjct: 868  TSGVVYVAGQLDRELVSVFYLKVEARDKAEQGSQRFSVTTLKVVLEDVNDCPPVFIPSVY 927

Query: 693  TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752
                 E+ P+GT +  +   DPD GP   V YS+   D +  F ++   G+ +     M 
Sbjct: 928  KTRALEDLPVGTVLAWLETQDPDLGPGGQVQYSL-ANDYNGWFEVDRTSGAIRL----MK 982

Query: 753  DLDYESPRKKYELVIRA---ASP-PLWNDVRVEILVTDVNDN--APVMKDFQIIFNNYKD 806
            +LDYE+ ++ Y L ++A     P  L +   VE+ V DVN+N  AP    F +     ++
Sbjct: 983  ELDYET-QQFYNLSVKAKDRGKPVALLSVTSVEVEVVDVNENLNAPYFSHFALKATVKEN 1041

Query: 807  CFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLAT 864
                    +V A D DV    ++QY I  G+      +NE TG +  +  L+        
Sbjct: 1042 ARIGTTLLQVAAQDDDVGRDGEIQYSIRDGSGLGRFAINEETGVIYTTDTLDRETKDSYW 1101

Query: 865  MEVSVTD 871
            + V  TD
Sbjct: 1102 LTVYATD 1108



 Score =  171 bits (416), Expect = 2e-40
 Identities = 165/570 (28%), Positives = 257/570 (45%), Gaps = 39/570 (6%)

Query: 103 ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162
           A L+RE    Y + VKA+ +   +   L +   + V ++D ND  P FS  TY+V++ E 
Sbjct: 103 AMLNREIQDNYLLTVKASVKGDAL---LETWTKVSVQVLDMNDLRPLFSPTTYSVTIMES 159

Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222
             +  +  IA++ ATDAD+G+N    Y +   N    F++   SG V L   L+ ++   
Sbjct: 160 TPLRTS--IAQVTATDADIGSNGEFYYFL--KNKMDLFAVHPTSGVVLLSGKLNVDERYQ 215

Query: 223 YRLVIRAQDGG-----SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277
           + L I A D G     +   S+T +L++++  VN++AP             N PI Y++V
Sbjct: 216 HDLEILAVDRGMKLYGNNGVSSTAKLIVHVERVNEHAPVISVVNSSPWSHANSPI-YAVV 274

Query: 278 RVQAYDADEGVNAEL-TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK-YQLL 335
            V+  D D G+N E+ +  +   D +    L  + +    ++  +  L+ ET  +   L 
Sbjct: 275 TVE--DPDPGLNGEVDSVVILGGDLSEKFFLERS-EENEFFIRATESLNWETHPRGCNLT 331

Query: 336 VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395
           + A D G P + +                 F    Y V L+E  PPGT V  +      E
Sbjct: 332 LQAADRGTPQKVSVKVVQIMDEKQSKVAAMFEKEVYNVSLSEFSPPGTVVQVVKIKP--E 389

Query: 396 DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMV 455
            + + Y +T       F +    G  +I+  Q      +  + L V   DS  +   A V
Sbjct: 390 SSYVEYTLTPSADSAFFRVNGVTG--VISTTQWFTGVSQSLFKLDVLEMDSELK---AQV 444

Query: 456 QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515
           Q+ I DAN+  P F  + Y   V E  P+GT+VL VSA D D G N  ITYS+SS  +  
Sbjct: 445 QVAIQDANDNTPTFHQSSYEILVNESVPVGTSVLTVSAQDGDDGENGYITYSISSLGA-- 502

Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMS-GYLLTVTARDGGVPSLSDT-TDVEISVVD 573
                   F IN  +G ITT + LD +  S  ++  V A D G P   ++   V I V +
Sbjct: 503 ------LPFQINQFSGVITTTEPLDFDFSSDSFVFIVRASDWGSPYRRESEVYVTIHVKN 556

Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633
           VNDN+P+F++      I  D      ++ V A D D      + Y++       G F ++
Sbjct: 557 VNDNQPLFEKTACHGVISRDLPADQVITTVSAIDIDE--LALVKYKI-VSGNTLGLFNLN 613

Query: 634 PASGVIRTNKAL-DRESVATHDLKAVAIDG 662
           P SGV+   ++L    S     LK  A DG
Sbjct: 614 PDSGVLSLQRSLVPAVSANAFSLKITATDG 643



 Score =  139 bits (337), Expect = 9e-31
 Identities = 146/608 (24%), Positives = 257/608 (42%), Gaps = 42/608 (6%)

Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380
           +  L+RE Q  Y L V A+  GD                      F P  Y V + E  P
Sbjct: 102 AAMLNREIQDNYLLTVKASVKGDALLETWTKVSVQVLDMNDLRPLFSPTTYSVTIMESTP 161

Query: 381 PGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440
             T +  +TATDAD  +   +     N    F++   +G  ++ ++  L+  +  ++ L 
Sbjct: 162 LRTSIAQVTATDADIGSNGEFYYFLKNKMDLFAVHPTSG--VVLLSGKLNVDERYQHDLE 219

Query: 441 VSATDSG-------GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
           + A D G       G S TA + +++   N +APV      +     ++PI     VV+ 
Sbjct: 220 ILAVDRGMKLYGNNGVSSTAKLIVHVERVNEHAPVISVVNSSPWSHANSPI---YAVVTV 276

Query: 494 TDSDVGINAQI--TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS-GYLLT 550
            D D G+N ++     L  ++S +      ++         I   + L+ ET   G  LT
Sbjct: 277 EDPDPGLNGEVDSVVILGGDLSEKFFLERSEE-----NEFFIRATESLNWETHPRGCNLT 331

Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610
           + A D G P       V+I     +    +F++++Y  ++ E +  GT V  V       
Sbjct: 332 LQAADRGTPQKVSVKVVQIMDEKQSKVAAMFEKEVYNVSLSEFSPPGTVVQVVKIKPE-- 389

Query: 611 GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST 670
             +  + Y L P   +   F ++  +GVI T +     S +   L  + +D     Q   
Sbjct: 390 --SSYVEYTLTPS-ADSAFFRVNGVTGVISTTQWFTGVSQSLFKLDVLEMDSELKAQ--- 443

Query: 671 VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD 730
             V + I+D ND+ P F        ++E+ P+GT++  + A D D+G N  + YSI    
Sbjct: 444 --VQVAIQDANDNTPTFHQSSYEILVNESVPVGTSVLTVSAQDGDDGENGYITYSI---- 497

Query: 731 DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SP-PLWNDVRVEILVTD 786
            S+  +L  +       + T   LD++     +  ++RA+   SP    ++V V I V +
Sbjct: 498 -SSLGALPFQINQFSGVITTTEPLDFDFSSDSFVFIVRASDWGSPYRRESEVYVTIHVKN 556

Query: 787 VNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETT 846
           VNDN P+ +         +D         V A D D    ++Y+I+SGN   L  LN  +
Sbjct: 557 VNDNQPLFEKTACHGVISRDLPADQVITTVSAIDIDELALVKYKIVSGNTLGLFNLNPDS 616

Query: 847 GSMTLSPQLNTNVPKLA-TMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTA 905
           G ++L   L   V   A +++++ TDG N +   M +++ ++  +    +I  +   M A
Sbjct: 617 GVLSLQRSLVPAVSANAFSLKITATDGEN-LSEPMYVNISVVEGKSFSKNINCK-ETMVA 674

Query: 906 EQFLSPLL 913
           ++    LL
Sbjct: 675 QRLAEKLL 682



 Score =  119 bits (286), Expect = 1e-24
 Identities = 136/575 (23%), Positives = 244/575 (42%), Gaps = 63/575 (10%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + VLD ND  P+F    Y  ++ E     T++  + ATD DIG N E  Y ++       
Sbjct: 135 VQVLDMNDLRPLFSPTTYSVTIMESTPLRTSIAQVTATDADIGSNGEFYYFLK------- 187

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV--SD 128
                            D+F +   SG +L    L+ ++  ++ + + A D+   +  ++
Sbjct: 188 --------------NKMDLFAVHPTSGVVLLSGKLNVDERYQHDLEILAVDRGMKLYGNN 233

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI- 187
            +SSTA + V++   N++ P  S     V      S  ++P+ A +   D D G N  + 
Sbjct: 234 GVSSTAKLIVHVERVNEHAPVIS-----VVNSSPWSHANSPIYAVVTVEDPDPGLNGEVD 288

Query: 188 RYAIIGGNTQMQFSIDSLSGD---VSLVKTLDYE-QVRSYRLVIRAQDGGSPSRSNTTQL 243
              I+GG+   +F ++    +   +   ++L++E   R   L ++A D G+P + +   +
Sbjct: 289 SVVILGGDLSEKFFLERSEENEFFIRATESLNWETHPRGCNLTLQAADRGTPQKVSVKVV 348

Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
            I     +  A  F   ++  S+SE  P G ++V+V     +   ++ + YT+T    + 
Sbjct: 349 QIMDEKQSKVAAMFEKEVYNVSLSEFSPPG-TVVQVVKIKPE---SSYVEYTLTPSADSA 404

Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
                  ++  +G + T+      +Q+ ++L V   D         A             
Sbjct: 405 F----FRVNGVTGVISTTQWFTGVSQSLFKLDVLEMDS-----ELKAQVQVAIQDANDNT 455

Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423
             F    YE+ + E  P GT V+T++A D D D    Y     ++ G          G+I
Sbjct: 456 PTFHQSSYEILVNESVPVGTSVLTVSAQDGD-DGENGYITYSISSLGALPFQINQFSGVI 514

Query: 424 TVAQPLDFK-QERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVF 479
           T  +PLDF      +V  V A+D G    R     V I++ + N+  P+FE       + 
Sbjct: 515 TTTEPLDFDFSSDSFVFIVRASDWGSPYRRESEVYVTIHVKNVNDNQPLFEKTACHGVIS 574

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK-L 538
            D P    +  VSA D D    A + Y +   +S   +      F +NP +G ++  + L
Sbjct: 575 RDLPADQVITTVSAIDIDE--LALVKYKI---VSGNTLG----LFNLNPDSGVLSLQRSL 625

Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
           +   + + + L +TA DG   +LS+   V ISVV+
Sbjct: 626 VPAVSANAFSLKITATDG--ENLSEPMYVNISVVE 658


>UniRef50_UPI0000E81ED5 Cluster: PREDICTED: similar to protocadherin
           beta 20; n=11; Gallus gallus|Rep: PREDICTED: similar to
           protocadherin beta 20 - Gallus gallus
          Length = 1166

 Score =  295 bits (725), Expect = 9e-78
 Identities = 244/839 (29%), Positives = 389/839 (46%), Gaps = 66/839 (7%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V+D ND++P+F    Y   + E A  G+ VL + ATD D+G N ++ Y    V + + 
Sbjct: 159 IIVMDVNDNAPIFTHDIYTGHIAESAPEGSLVLRVMATDADVGTNGDISYQFSQVVSQS- 217

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           Q  F I+  +G +  +  LD E   +Y + V+ATD        L
Sbjct: 218 ----------------QSAFTINTTNGEIRVKTPLDFETTHKYELGVRATDGGG-----L 256

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           S+   + V ++D NDN P+    +++  + E++      V+A +   D D GAN  I  A
Sbjct: 257 SALCKVLVEVMDVNDNAPEIVVSSFSSPIPENVET--GTVVALLAVRDQDSGANGEISCA 314

Query: 191 IIGGNTQMQFSIDSLSG---DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
           +     Q  F++        ++  V TLD E+   + +V+ A D GSP  ++T    ++I
Sbjct: 315 L---EEQPSFALRPAFKNYYELVTVSTLDREERAQHMVVVTAADAGSPPLTSTHTFSVDI 371

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            DVNDNAP F  + +   V EN      +  V+A DAD G NA+++Y++      G  + 
Sbjct: 372 SDVNDNAPVFNQTSYTMYVHENNAPALLVGAVKATDADAGPNAKVSYSVVPA--RGPEEE 429

Query: 308 P---ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
           P   ++++  SG V+    LD E   + +++V+A D G PP S++ +             
Sbjct: 430 PCSCVSVNSESGGVFVLRPLDYEQLRQLEVVVSAADAGSPPLSSSVSVRLLVVDENDNAP 489

Query: 365 XFM-PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423
             + P   +      E  G P   L A  A    R+       +  GR     + G G +
Sbjct: 490 LVLHPSAQDSSPPSSETRGWPRRKLLAFRA----RI------ASPAGRQHFRLERGSGRL 539

Query: 424 TVAQPLDFKQERRYVLTVSATDSGGRSDTAM---VQINITDANNYAPVFENAPYTASVFE 480
            VA+ LD ++      T +       +D      +++++ D N+++PVF +   T  + E
Sbjct: 540 VVAERLDREEMCGRSRTCTLAFELLLADPLQFFPIEVSVEDINDHSPVFPDERVTFKIAE 599

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ-QFVINPQTGAITTNKLL 539
               G+   V  A D DV  N    YS+  E     V++  + +  I  Q   +   + L
Sbjct: 600 LTEPGSRFPVEGAQDFDVDSNDIQAYSIIPENKFFTVSYEKKNEGDIQVQ---LVLQQPL 656

Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
           DRE  S    T+ A DGG P  S TT + I V+DVNDN P+F   +YT +I E A  G+ 
Sbjct: 657 DREEQSELDFTLVATDGGSPPRSGTTQIHIIVMDVNDNAPIFTHDIYTGHIAESAPEGSL 716

Query: 600 VSQVGATDADVGLNGRIHYELDP-KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
           V +V ATDADVG NG I Y+      + + +F I+  +G IR    LD E+   ++L   
Sbjct: 717 VLRVMATDADVGTNGDISYQFSQVVSQSQSAFTINTTNGEIRVKTPLDFETTHKYELGVR 776

Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
           A DGG    S+   V +++ D+ND+ P       +  I EN   GT +  +   D D G 
Sbjct: 777 ATDGG--GLSALCKVLVEVMDVNDNAPEIVVSSFSSPIPENVEPGTVVALLAVRDQDSGV 834

Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLW 775
           N  +  ++   ++  SF+L      +  ELVT+  LD E  R ++ +V+ AA   SPPL 
Sbjct: 835 NGEITCAL---EEQLSFALRP-AFKNYYELVTVSRLDREE-RAQHMVVVTAADAGSPPLT 889

Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRIL 832
           +     + ++DVNDNAPV          +++  P    G V A DAD     K+ Y ++
Sbjct: 890 STHTFSVDISDVNDNAPVFNQTSYTMYVHENNAPALLVGAVKATDADAGPNAKVSYSVV 948



 Score =  272 bits (667), Expect = 9e-71
 Identities = 214/714 (29%), Positives = 334/714 (46%), Gaps = 55/714 (7%)

Query: 99  LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158
           L+ +  LDRE+ +     + ATD  SP     S T  IH+ ++D NDN P F+   YT  
Sbjct: 123 LVLQHPLDREEQSELDFTLVATDGGSPPR---SGTTQIHIIVMDVNDNAPIFTHDIYTGH 179

Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAI--IGGNTQMQFSIDSLSGDVSLVKTLD 216
           + E  S  +  ++ ++ ATDADVG N  I Y    +   +Q  F+I++ +G++ +   LD
Sbjct: 180 IAE--SAPEGSLVLRVMATDADVGTNGDISYQFSQVVSQSQSAFTINTTNGEIRVKTPLD 237

Query: 217 YEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSI 276
           +E    Y L +RA DGG    S   ++L+ + DVNDNAP    S F   + ENV  G  +
Sbjct: 238 FETTHKYELGVRATDGG--GLSALCKVLVEVMDVNDNAPEIVVSSFSSPIPENVETGTVV 295

Query: 277 VRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY---TSGQLDRETQAKYQ 333
             +   D D G N E++  + ++           + P     Y   T   LDRE +A++ 
Sbjct: 296 ALLAVRDQDSGANGEISCALEEQP-------SFALRPAFKNYYELVTVSTLDREERAQHM 348

Query: 334 LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393
           ++VTA D G PP ++T T              F    Y + + E+  P   V  + ATDA
Sbjct: 349 VVVTAADAGSPPLTSTHTFSVDISDVNDNAPVFNQTSYTMYVHENNAPALLVGAVKATDA 408

Query: 394 D--EDNRLHYEI--TGGNTRGRFSITSQNGR-GLITVAQPLDFKQERRYVLTVSATDSGG 448
           D   + ++ Y +    G      S  S N   G + V +PLD++Q R+  + VSA D+G 
Sbjct: 409 DAGPNAKVSYSVVPARGPEEEPCSCVSVNSESGGVFVLRPLDYEQLRQLEVVVSAADAGS 468

Query: 449 --RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506
              S +  V++ + D N+ AP+  +     S  + +P          +    G   +   
Sbjct: 469 PPLSSSVSVRLLVVDENDNAPLVLH----PSAQDSSP---------PSSETRGWPRRKLL 515

Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT-ARDGGVPSLSDTT 565
           +  + I++ A   H   F +   +G +   + LDRE M G   T T A +  +       
Sbjct: 516 AFRARIASPAGRQH---FRLERGSGRLVVAERLDREEMCGRSRTCTLAFELLLADPLQFF 572

Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625
            +E+SV D+ND+ PVF  +  T  I E    G+     GA D DV  N    Y + P+++
Sbjct: 573 PIEVSVEDINDHSPVFPDERVTFKIAELTEPGSRFPVEGAQDFDVDSNDIQAYSIIPENK 632

Query: 626 EEGSFVIDPASGVIRT----NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681
                      G I+      + LDRE  +  D   VA DGG+PP+S T  +HI + D+N
Sbjct: 633 FFTVSYEKKNEGDIQVQLVLQQPLDREEQSELDFTLVATDGGSPPRSGTTQIHIIVMDVN 692

Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG--GDDSNSFSLET 739
           D+ P+F  D  T +I+E++P G+ +  + A D D G N  + Y          ++F++ T
Sbjct: 693 DNAPIFTHDIYTGHIAESAPEGSLVLRVMATDADVGTNGDISYQFSQVVSQSQSAFTINT 752

Query: 740 RQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAP 792
             G    E+     LD+E+   KYEL +RA     L    +V + V DVNDNAP
Sbjct: 753 TNG----EIRVKTPLDFETTH-KYELGVRATDGGGLSALCKVLVEVMDVNDNAP 801



 Score =  244 bits (596), Expect = 4e-62
 Identities = 199/746 (26%), Positives = 333/746 (44%), Gaps = 54/746 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +++ D ND++PVF    Y   V E  +    V  +KATD D G NA+V Y++        
Sbjct: 369  VDISDVNDNAPVFNQTSYTMYVHENNAPALLVGAVKATDADAGPNAKVSYSV----VPAR 424

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             PE+                 ++  SG +     LD E++ +  V+V A D  SP    L
Sbjct: 425  GPEEEPCSCVS----------VNSESGGVFVLRPLDYEQLRQLEVVVSAADAGSPP---L 471

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            SS+ ++ + ++D+NDN P     +   S          P   K+ A  A + + +     
Sbjct: 472  SSSVSVRLLVVDENDNAPLVLHPSAQDSSPPSSETRGWPR-RKLLAFRARIASPAG---- 526

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDGGSPSRSNTTQLLINIR 248
                  +  F ++  SG + + + LD E++  RS R    A +           + +++ 
Sbjct: 527  ------RQHFRLERGSGRLVVAERLDREEMCGRS-RTCTLAFELLLADPLQFFPIEVSVE 579

Query: 249  DVNDNAPRFYTSLFQESVSENVPIG--YSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            D+ND++P F        ++E    G  + +   Q +D D       +    +K +T + +
Sbjct: 580  DINDHSPVFPDERVTFKIAELTEPGSRFPVEGAQDFDVDSNDIQAYSIIPENKFFTVSYE 639

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
                 D +   V     LDRE Q++    + ATDGG PPRS T                F
Sbjct: 640  KKNEGDIQVQLVLQQ-PLDREEQSELDFTLVATDGGSPPRSGTTQIHIIVMDVNDNAPIF 698

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLIT 424
                Y   +AE  P G+ V+ + ATDAD   +  + Y+ +   ++ + + T     G I 
Sbjct: 699  THDIYTGHIAESAPEGSLVLRVMATDADVGTNGDISYQFSQVVSQSQSAFTINTTNGEIR 758

Query: 425  VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
            V  PLDF+   +Y L V ATD GG S    V + + D N+ AP    + +++ + E+   
Sbjct: 759  VKTPLDFETTHKYELGVRATDGGGLSALCKVLVEVMDVNDNAPEIVVSSFSSPIPENVEP 818

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            GT V +++  D D G+N +IT +L  ++S          + +      +T ++L DRE  
Sbjct: 819  GTVVALLAVRDQDSGVNGEITCALEEQLSFALRPAFKNYYEL------VTVSRL-DREER 871

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
            + +++ VTA D G P L+ T    + + DVNDN PVF Q  YT  + E+      V  V 
Sbjct: 872  AQHMVVVTAADAGSPPLTSTHTFSVDISDVNDNAPVFNQTSYTMYVHENNAPALLVGAVK 931

Query: 605  ATDADVGLNGRIHYELDP---KDREEGSFV-IDPASGVIRTNKALDRESVATHDLKAVAI 660
            ATDAD G N ++ Y + P    + E  S V ++  SG +   + LD E +   ++   A 
Sbjct: 932  ATDADAGPNAKVSYSVVPARGPEEEPCSCVSVNSESGGVFVLRPLDYEQLRQLEVVVSAA 991

Query: 661  DGGTPPQSSTVIVHIKIEDINDSPPVF-------ESDCLTFYISENSPIGTTIGEIRAHD 713
            D G+PP SS+V V + + D ND+ P+         S   +  +   +  G  + ++ A D
Sbjct: 992  DAGSPPLSSSVSVRLLVVDENDNAPLVLHPSAQDSSPPSSELVPAGAEAGDLVSKVVAVD 1051

Query: 714  PDEGPNAVVHYSIKGGDDSNSFSLET 739
             D G N+ + Y +    +   F++ T
Sbjct: 1052 ADSGQNSWLSYQLLRATEPGLFAIGT 1077



 Score =  220 bits (538), Expect = 4e-55
 Identities = 195/672 (29%), Positives = 306/672 (45%), Gaps = 34/672 (5%)

Query: 215 LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY 274
           LD E+       + A DGGSP RS TTQ+ I + DVNDNAP F   ++   ++E+ P G 
Sbjct: 129 LDREEQSELDFTLVATDGGSPPRSGTTQIHIIVMDVNDNAPIFTHDIYTGHIAESAPEGS 188

Query: 275 SIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQL 334
            ++RV A DAD G N +++Y  +            TI+  +G +     LD ET  KY+L
Sbjct: 189 LVLRVMATDADVGTNGDISYQFS--QVVSQSQSAFTINTTNGEIRVKTPLDFETTHKYEL 246

Query: 335 LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394
            V ATDGG    SA                  +   +   + E+   GT VV L A   D
Sbjct: 247 GVRATDGGG--LSALCKVLVEVMDVNDNAPEIVVSSFSSPIPENVETGT-VVALLAV-RD 302

Query: 395 EDNRLHYEITGG-NTRGRFSI--TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--R 449
           +D+  + EI+     +  F++    +N   L+TV+  LD ++  ++++ V+A D+G    
Sbjct: 303 QDSGANGEISCALEEQPSFALRPAFKNYYELVTVS-TLDREERAQHMVVVTAADAGSPPL 361

Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509
           + T    ++I+D N+ APVF    YT  V E+      V  V ATD+D G NA+++YS+ 
Sbjct: 362 TSTHTFSVDISDVNDNAPVFNQTSYTMYVHENNAPALLVGAVKATDADAGPNAKVSYSVV 421

Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569
                E          +N ++G +   + LD E +    + V+A D G P LS +  V +
Sbjct: 422 PARGPE--EEPCSCVSVNSESGGVFVLRPLDYEQLRQLEVVVSAADAGSPPLSSSVSVRL 479

Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629
            VVD NDN P+    L+ +   +D+   +S ++       +    RI     P  R+   
Sbjct: 480 LVVDENDNAPLV---LHPS--AQDSSPPSSETRGWPRRKLLAFRARI---ASPAGRQH-- 529

Query: 630 FVIDPASGVIRTNKALDRESVATHDLK-AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688
           F ++  SG +   + LDRE +        +A +           + + +EDIND  PVF 
Sbjct: 530 FRLERGSGRLVVAERLDREEMCGRSRTCTLAFELLLADPLQFFPIEVSVEDINDHSPVFP 589

Query: 689 SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR-QGSDKAE 747
            + +TF I+E +  G+      A D D   N +  YSI   +   + S E + +G  + +
Sbjct: 590 DERVTFKIAELTEPGSRFPVEGAQDFDVDSNDIQAYSIIPENKFFTVSYEKKNEGDIQVQ 649

Query: 748 LVTMVDLDYESPRK-KYELVIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYK 805
           LV    LD E   +  + LV     SPP     ++ I+V DVNDNAP+     I   +  
Sbjct: 650 LVLQQPLDREEQSELDFTLVATDGGSPPRSGTTQIHIIVMDVNDNAPIF-THDIYTGHIA 708

Query: 806 DCFPVGPFG-RVPAYDADVTD----KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVP 860
           +  P G    RV A DADV        Q+  +   + +   +N T G + +   L+    
Sbjct: 709 ESAPEGSLVLRVMATDADVGTNGDISYQFSQVVSQSQSAFTINTTNGEIRVKTPLDFETT 768

Query: 861 KLATMEVSVTDG 872
               + V  TDG
Sbjct: 769 HKYELGVRATDG 780



 Score =  220 bits (538), Expect = 4e-55
 Identities = 156/437 (35%), Positives = 218/437 (49%), Gaps = 30/437 (6%)

Query: 374  ELAEDEPPGT--PVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL---ITVAQP 428
            ++AE   PG+  PV      D D ++   Y I   N     S   +N   +   + + QP
Sbjct: 596  KIAELTEPGSRFPVEGAQDFDVDSNDIQAYSIIPENKFFTVSYEKKNEGDIQVQLVLQQP 655

Query: 429  LDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
            LD +++     T+ ATD G   RS T  + I + D N+ AP+F +  YT  + E AP G+
Sbjct: 656  LDREEQSELDFTLVATDGGSPPRSGTTQIHIIVMDVNDNAPIFTHDIYTGHIAESAPEGS 715

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
             VL V ATD+DVG N  I+Y  S  +S    A     F IN   G I     LD ET   
Sbjct: 716  LVLRVMATDADVGTNGDISYQFSQVVSQSQSA-----FTINTTNGEIRVKTPLDFETTHK 770

Query: 547  YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
            Y L V A DGG   LS    V + V+DVNDN P      +++ I E+   GT V+ +   
Sbjct: 771  YELGVRATDGG--GLSALCKVLVEVMDVNDNAPEIVVSSFSSPIPENVEPGTVVALLAVR 828

Query: 607  DADVGLNGRIHYELDPKDREEGSFVIDPASG---VIRTNKALDRESVATHDLKAVAIDGG 663
            D D G+NG I   L+    E+ SF + PA      + T   LDRE  A H +   A D G
Sbjct: 829  DQDSGVNGEITCALE----EQLSFALRPAFKNYYELVTVSRLDREERAQHMVVVTAADAG 884

Query: 664  TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
            +PP +ST    + I D+ND+ PVF     T Y+ EN+     +G ++A D D GPNA V 
Sbjct: 885  SPPLTSTHTFSVDISDVNDNAPVFNQTSYTMYVHENNAPALLVGAVKATDADAGPNAKVS 944

Query: 724  YSI---KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWND 777
            YS+   +G ++     +     S+   +  +  LDYE  R+  E+V+ AA   SPPL + 
Sbjct: 945  YSVVPARGPEEEPCSCVSVN--SESGGVFVLRPLDYEQLRQ-LEVVVSAADAGSPPLSSS 1001

Query: 778  VRVEILVTDVNDNAPVM 794
            V V +LV D NDNAP++
Sbjct: 1002 VSVRLLVVDENDNAPLV 1018



 Score = 74.1 bits (174), Expect = 5e-11
 Identities = 53/200 (26%), Positives = 91/200 (45%), Gaps = 22/200 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +++ D ND++PVF    Y   V E  +    V  +KATD D G NA+V Y++        
Sbjct: 896  VDISDVNDNAPVFNQTSYTMYVHENNAPALLVGAVKATDADAGPNAKVSYSV----VPAR 951

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             PE+                 ++  SG +     LD E++ +  V+V A D  SP    L
Sbjct: 952  GPEEEPCSCVS----------VNSESGGVFVLRPLDYEQLRQLEVVVSAADAGSPP---L 998

Query: 131  SSTATIHVNIIDDNDN-----YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
            SS+ ++ + ++D+NDN     +P   + +   S           +++K+ A DAD G NS
Sbjct: 999  SSSVSVRLLVVDENDNAPLVLHPSAQDSSPPSSELVPAGAEAGDLVSKVVAVDADSGQNS 1058

Query: 186  AIRYAIIGGNTQMQFSIDSL 205
             + Y ++       F+I ++
Sbjct: 1059 WLSYQLLRATEPGLFAIGTV 1078


>UniRef50_UPI00015B6339 Cluster: PREDICTED: similar to
            ENSANGP00000011295; n=1; Nasonia vitripennis|Rep:
            PREDICTED: similar to ENSANGP00000011295 - Nasonia
            vitripennis
          Length = 1949

 Score =  294 bits (722), Expect = 2e-77
 Identities = 262/883 (29%), Positives = 413/883 (46%), Gaps = 89/883 (10%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++++ D ND  P F+ ++Y A + EGA      L ++A D+D  K +++ Y+I  V  + 
Sbjct: 661  RLSLADANDSPPKFQHKKYRAVIDEGAEKFEPPLRVQARDRD--KTSKITYSI--VEGNK 716

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSG--ALLTRASLDREKVARYTVLVKATDQASPVS 127
            +                  +FRID  SG   +  RA +D          +  T QAS   
Sbjct: 717  MG-----------------IFRIDSDSGEITIAKRAPVDMSNSTNGGDSISLTVQAS--D 757

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
               S  A I + + D N+N P F+   YT S+ E   V    V+ ++ ATDAD G N+ +
Sbjct: 758  GTFSDKALISITVRDVNNNAPAFAHDLYTASIPELSPV--GTVVEELTATDADSGINAEL 815

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
             Y I  G     F+++  SG V + + LDY+Q  +Y + + A D GSPS + TT L+IN+
Sbjct: 816  VYRIQKGGFN-DFAVNETSGAVFVSRKLDYDQRNTYHVEVIAFDKGSPSLTGTTTLMINV 874

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD----EGVNAELTYTMTDKDYTG 303
             + ND  P F     +  V+E+  IG     ++A D D    E +N  ++  +T  D  G
Sbjct: 875  ENSNDKPPYFSPGTQRAEVTEDTAIGTVFTTLKAIDPDSTDPEALNFAISEPITAIDRNG 934

Query: 304  -NVDLPIT-------IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP-RSATATXXX 354
              V+   T       +D ++G V     LDR+  A   L +  TD   P  +        
Sbjct: 935  QRVNDSTTAFKDFFAVDRKTGQVSVVKSLDRDIAATVSLTLVVTDTSAPTLQQGKGNLVV 994

Query: 355  XXXXXXXXXXXFM------PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT 408
                       F         +Y +E+ E++P G  V   TATDAD +N   Y I   + 
Sbjct: 995  TIIDVNHFAPEFARPWTREDPKYSIEMQEEQPTGAIVGAFTATDAD-NNIAGYAIEPPSP 1053

Query: 409  RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYA 466
               F I   N  G++  +Q +D+++ ++   TV A D+G    S +A V + I + N+  
Sbjct: 1054 --YFHI--NNVTGIVRTSQIIDYEETKQLEFTVVAYDTGVPQLSTSAKVTVTIINVNDED 1109

Query: 467  PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
            P FE+  Y A+V E++  GT V VV A D+D G   ++TYSL        +  H   F I
Sbjct: 1110 PKFEHKSYNATVKENSQPGTRVTVVKAIDADEGPFGEVTYSL--------IGEHASDFNI 1161

Query: 527  NPQTGAITTN--KLLDRETMSGYLLTVTARDGGVPSLSDTTDVE--ISVVDVNDNEPVFK 582
              +TG IT     +LDRE +    ++V A D    +   +T V   I +VDVNDN P+F 
Sbjct: 1162 GHETGEITVGGATVLDREIIPEITISVMASDNAPMNSRRSTSVPVVIKLVDVNDNRPIFT 1221

Query: 583  QQLYTANIMEDALVG--TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640
            Q  Y A++ E+  V     + QV A D D G+NG + Y++  K  E GSF ++P +G++ 
Sbjct: 1222 QHSYRASVAENLSVNPPAPILQVRAVDNDEGVNGEVWYKI-IKGNENGSFALNPETGILY 1280

Query: 641  TNKALDRESVATHDLKAVAID-GGTPPQSSTVIVHIKIEDINDSPPVF---ESDCLTFYI 696
               +L      ++ +K  A D  G  P   T  +++++  +N   P F   E    T  +
Sbjct: 1281 PAVSL-LGRAQSYKIKVEARDMAGKGPHFDTCNIYVRVIPVNQHKPEFIMPELPNATVEV 1339

Query: 697  SEN-SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755
             EN       +  ++A D D G N  V Y +K G+ +   + E     +  EL   + LD
Sbjct: 1340 PENGGEPNYLVMTVKAIDRDSGDNGKVSYHMKVGNRNVQETEEFSINQETGELRAKIILD 1399

Query: 756  YESPRKKYELVIRAA---SPPLWNDVR-VEILVTDVNDNAPVMKD---FQIIFNNYKDCF 808
             E+ + K+ELV+ AA   SP  +  +R + +L+ D NDN P   +   F +  N  KD +
Sbjct: 1400 RET-KNKFELVLVAADHGSPTAYETLRLLTVLLIDTNDNVPEFYEEYNFNVPENRPKDYY 1458

Query: 809  PVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSM 849
                 G+V A D D     K+ Y I +GN      ++++ GS+
Sbjct: 1459 ----VGKVTAEDKDEGRHAKVYYYIKAGNADRAFYIDKSDGSI 1497



 Score =  246 bits (603), Expect = 5e-63
 Identities = 202/699 (28%), Positives = 324/699 (46%), Gaps = 65/699 (9%)

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +++ ++ +++ D ND+ P+F  K Y   +DE     + P+  +++A D D    S I Y+
Sbjct: 655  TTSVSLRLSLADANDSPPKFQHKKYRAVIDEGAEKFEPPL--RVQARDRD--KTSKITYS 710

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR------LVIRAQDGGSPSRSNTTQLL 244
            I+ GN    F IDS SG++++ K    +   S        L ++A DG   + S+   + 
Sbjct: 711  IVEGNKMGIFRIDSDSGEITIAKRAPVDMSNSTNGGDSISLTVQASDG---TFSDKALIS 767

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
            I +RDVN+NAP F   L+  S+ E  P+G  +  + A DAD G+NAEL Y +    +   
Sbjct: 768  ITVRDVNNNAPAFAHDLYTASIPELSPVGTVVEELTATDADSGINAELVYRIQKGGFND- 826

Query: 305  VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
                  ++  SG V+ S +LD + +  Y + V A D G P  + T T             
Sbjct: 827  ----FAVNETSGAVFVSRKLDYDQRNTYHVEVIAFDKGSPSLTGTTTLMINVENSNDKPP 882

Query: 365  XFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNT-------RGRFSIT 415
             F PG    E+ ED   GT   TL A D D  +   L++ I+   T       R   S T
Sbjct: 883  YFSPGTQRAEVTEDTAIGTVFTTLKAIDPDSTDPEALNFAISEPITAIDRNGQRVNDSTT 942

Query: 416  S-------QNGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNY 465
            +           G ++V + LD        LT+  TD+     +     + + I D N++
Sbjct: 943  AFKDFFAVDRKTGQVSVVKSLDRDIAATVSLTLVVTDTSAPTLQQGKGNLVVTIIDVNHF 1002

Query: 466  APVF------ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAH 519
            AP F      E+  Y+  + E+ P G  V   +ATD+D            + I+  A+  
Sbjct: 1003 APEFARPWTREDPKYSIEMQEEQPTGAIVGAFTATDAD------------NNIAGYAIEP 1050

Query: 520  HDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP 579
                F IN  TG + T++++D E       TV A D GVP LS +  V +++++VND +P
Sbjct: 1051 PSPYFHINNVTGIVRTSQIIDYEETKQLEFTVVAYDTGVPQLSTSAKVTVTIINVNDEDP 1110

Query: 580  VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639
             F+ + Y A + E++  GT V+ V A DAD G  G + Y L  +   +  F I   +G I
Sbjct: 1111 KFEHKSYNATVKENSQPGTRVTVVKAIDADEGPFGEVTYSLIGEHASD--FNIGHETGEI 1168

Query: 640  RTNKA--LDRESVATHDLKAVAIDGG--TPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695
                A  LDRE +    +  +A D       +S++V V IK+ D+ND+ P+F        
Sbjct: 1169 TVGGATVLDREIIPEITISVMASDNAPMNSRRSTSVPVVIKLVDVNDNRPIFTQHSYRAS 1228

Query: 696  ISENSPIG--TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753
            ++EN  +     I ++RA D DEG N  V Y I  G+++ SF+L    G      V+++ 
Sbjct: 1229 VAENLSVNPPAPILQVRAVDNDEGVNGEVWYKIIKGNENGSFALNPETGI-LYPAVSLLG 1287

Query: 754  LDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP 792
               +S + K E    A   P ++   + + V  VN + P
Sbjct: 1288 -RAQSYKIKVEARDMAGKGPHFDTCNIYVRVIPVNQHKP 1325



 Score =  236 bits (578), Expect = 6e-60
 Identities = 222/820 (27%), Positives = 364/820 (44%), Gaps = 72/820 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI-ELVTADT 69
            INV + ND  P F      A V E  + GT   TLKA D D      + + I E +TA  
Sbjct: 872  INVENSNDKPPYFSPGTQRAEVTEDTAIGTVFTTLKAIDPDSTDPEALNFAISEPITAID 931

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             N +             +D F +D ++G +    SLDR+  A  ++ +  TD ++P   +
Sbjct: 932  RNGQRVNDSTTAF----KDFFAVDRKTGQVSVVKSLDRDIAATVSLTLVVTDTSAPTLQQ 987

Query: 130  LSSTATIHVNIIDDNDNYPQFS------EKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183
                  + V IID N   P+F+      +  Y++ + E+       ++    ATDAD   
Sbjct: 988  --GKGNLVVTIIDVNHFAPEFARPWTREDPKYSIEMQEEQPT--GAIVGAFTATDAD--- 1040

Query: 184  NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
            N+   YAI   +    F I++++G V   + +DYE+ +     + A D G P  S + ++
Sbjct: 1041 NNIAGYAIEPPSPY--FHINNVTGIVRTSQIIDYEETKQLEFTVVAYDTGVPQLSTSAKV 1098

Query: 244  LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
             + I +VND  P+F    +  +V EN   G  +  V+A DADEG   E+TY++      G
Sbjct: 1099 TVTIINVNDEDPKFEHKSYNATVKENSQPGTRVTVVKAIDADEGPFGEVTYSL-----IG 1153

Query: 304  NVDLPITIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGG--DPPRSATATXXXXXXXX 359
                   I   +G +   G   LDRE   +  + V A+D    +  RS +          
Sbjct: 1154 EHASDFNIGHETGEITVGGATVLDREIIPEITISVMASDNAPMNSRRSTSVPVVIKLVDV 1213

Query: 360  XXXXXXFMPGQYEVELAED--EPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSIT 415
                  F    Y   +AE+    P  P++ + A D DE  +  + Y+I  GN  G F++ 
Sbjct: 1214 NDNRPIFTQHSYRASVAENLSVNPPAPILQVRAVDNDEGVNGEVWYKIIKGNENGSFALN 1273

Query: 416  SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS---DTAMVQINITDANNYAPVF--- 469
             +   G++  A  L   + + Y + V A D  G+    DT  + + +   N + P F   
Sbjct: 1274 PET--GILYPAVSL-LGRAQSYKIKVEARDMAGKGPHFDTCNIYVRVIPVNQHKPEFIMP 1330

Query: 470  ENAPYTASVFED-APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528
            E    T  V E+       V+ V A D D G N +++Y +  ++ N  V    ++F IN 
Sbjct: 1331 ELPNATVEVPENGGEPNYLVMTVKAIDRDSGDNGKVSYHM--KVGNRNV-QETEEFSINQ 1387

Query: 529  QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD-VEISVVDVNDNEPVFKQQLYT 587
            +TG +    +LDRET + + L + A D G P+  +T   + + ++D NDN P F ++ Y 
Sbjct: 1388 ETGELRAKIILDRETKNKFELVLVAADHGSPTAYETLRLLTVLLIDTNDNVPEFYEE-YN 1446

Query: 588  ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647
             N+ E+      V +V A D D G + +++Y +   + +  +F ID + G I TN++ DR
Sbjct: 1447 FNVPENRPKDYYVGKVTAEDKDEGRHAKVYYYIKAGNADR-AFYIDKSDGSIYTNRSFDR 1505

Query: 648  ESVATHDLKAVA-------IDGGTPPQSSTVIVH------IKIEDINDSPPVFESDCLTF 694
            E   ++ L  +A       +D      S   + H      IKI D ND+PP FE      
Sbjct: 1506 EKRDSYLLTILAANDPDIYVDPKDTDHSRKNLEHGYVNVTIKILDENDNPPAFERSAYFA 1565

Query: 695  YISENSPIGTTIGEIRAHDPDEGPNAVVHYSI------KGGDDSNSFSL--ETRQGSDKA 746
             ++  + I   + ++ A D D G N  + Y +      K G D  S S+       +   
Sbjct: 1566 GVNSMANINELVTKVTASDADLGDNGTLQYYVASANLYKYGSDKPSGSIVPSPFNVTQDG 1625

Query: 747  ELVTMVDL-DYESPRKKYELVIR-AASPPLWNDVRVEILV 784
            +LVT   + +Y   R   E+V +  ASP  +   +V + V
Sbjct: 1626 KLVTSGYMAEYNQDRFIVEIVAKEIASPERFAVTKVHVWV 1665



 Score =  194 bits (472), Expect = 4e-47
 Identities = 176/677 (25%), Positives = 292/677 (43%), Gaps = 51/677 (7%)

Query: 201  SIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260
            ++ +  GD  + + + YE V S      A D     ++ +  L +++ D ND+ P+F   
Sbjct: 622  TVKARDGDRGMPRKIVYELVTSES----ATDDNGKGQTTSVSLRLSLADANDSPPKFQHK 677

Query: 261  LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT 320
             ++  + E        +RVQA D D+   +++TY++ +    GN      ID  SG +  
Sbjct: 678  KYRAVIDEGAEKFEPPLRVQARDRDK--TSKITYSIVE----GNKMGIFRIDSDSGEITI 731

Query: 321  SGQ----LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376
            + +    +   T     + +T     D   S  A               F    Y   + 
Sbjct: 732  AKRAPVDMSNSTNGGDSISLTV-QASDGTFSDKALISITVRDVNNNAPAFAHDLYTASIP 790

Query: 377  EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR-GLITVAQPLDFKQER 435
            E  P GT V  LTATDAD    ++ E+     +G F+  + N   G + V++ LD+ Q  
Sbjct: 791  ELSPVGTVVEELTATDADSG--INAELVYRIQKGGFNDFAVNETSGAVFVSRKLDYDQRN 848

Query: 436  RYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
             Y + V A D G  S   T  + IN+ ++N+  P F      A V ED  IGT    + A
Sbjct: 849  TYHVEVIAFDKGSPSLTGTTTLMINVENSNDKPPYFSPGTQRAEVTEDTAIGTVFTTLKA 908

Query: 494  TDSDVGINAQITYSLSSEIS---------NEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
             D D      + +++S  I+         N++       F ++ +TG ++  K LDR+  
Sbjct: 909  IDPDSTDPEALNFAISEPITAIDRNGQRVNDSTTAFKDFFAVDRKTGQVSVVKSLDRDIA 968

Query: 545  SGYLLTVTARDGGVPSLSD-TTDVEISVVDVNDNEPVF------KQQLYTANIMEDALVG 597
            +   LT+   D   P+L     ++ ++++DVN   P F      +   Y+  + E+   G
Sbjct: 969  ATVSLTLVVTDTSAPTLQQGKGNLVVTIIDVNHFAPEFARPWTREDPKYSIEMQEEQPTG 1028

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
              V    ATDAD  + G   Y ++P       F I+  +G++RT++ +D E     +   
Sbjct: 1029 AIVGAFTATDADNNIAG---YAIEP---PSPYFHINNVTGIVRTSQIIDYEETKQLEFTV 1082

Query: 658  VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
            VA D G P  S++  V + I ++ND  P FE       + ENS  GT +  ++A D DEG
Sbjct: 1083 VAYDTGVPQLSTSAKVTVTIINVNDEDPKFEHKSYNATVKENSQPGTRVTVVKAIDADEG 1142

Query: 718  PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP---PL 774
            P   V YS+  G+ ++ F++    G       T++D +   P     ++    +P     
Sbjct: 1143 PFGEVTYSLI-GEHASDFNIGHETGEITVGGATVLDREI-IPEITISVMASDNAPMNSRR 1200

Query: 775  WNDVRVEILVTDVNDNAPV--MKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYR 830
               V V I + DVNDN P+     ++          P  P  +V A D D  V  ++ Y+
Sbjct: 1201 STSVPVVIKLVDVNDNRPIFTQHSYRASVAENLSVNPPAPILQVRAVDNDEGVNGEVWYK 1260

Query: 831  ILSGNNANLILLNETTG 847
            I+ GN      LN  TG
Sbjct: 1261 IIKGNENGSFALNPETG 1277



 Score =  151 bits (367), Expect = 2e-34
 Identities = 161/642 (25%), Positives = 278/642 (43%), Gaps = 71/642 (11%)

Query: 169 PVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIR 228
           PV  K+          S ++Y +       +F +D  +G ++L K LD E+  + R  + 
Sbjct: 401 PVGTKVFTLKGHDPEGSPVKYGV---QLTDKFVVDQRTGVMTLAKPLDREEADTIRFRVT 457

Query: 229 AQDG---GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV-RVQAYDA 284
            +D    G        +  + + D NDN P+F    ++  V+E+ P G +I+  ++  D 
Sbjct: 458 LEDSVPQGQQPNIVGVEAHVIVLDENDNPPQFLGVPYEAVVAEDSPPGTTILPAIRVTDP 517

Query: 285 DE-GVNAELTYTMTDK-----DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA 338
           D  G N ++T     +        G V++  + D   G +     LD + +  YQLL+ A
Sbjct: 518 DLLGENIQVTCIPQPQFPDACTKFGIVNIERSQDTYIGALVLQQPLDYKERPFYQLLLQA 577

Query: 339 TDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--D 396
           +DG +   +                   + G     + ED+P GT V+T+ A D D    
Sbjct: 578 SDGSNSNSTGVEIKVTDIQNSPPEFLDSLTG----VVKEDDPIGTLVMTVKARDGDRGMP 633

Query: 397 NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ 456
            ++ YE+         S T  NG+G  T              L +S  D           
Sbjct: 634 RKIVYELVTSE-----SATDDNGKGQTTSVS-----------LRLSLAD----------- 666

Query: 457 INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL--SSEISN 514
                AN+  P F++  Y A + E A      L V A D D    ++ITYS+   +++  
Sbjct: 667 -----ANDSPPKFQHKKYRAVIDEGAEKFEPPLRVQARDRDK--TSKITYSIVEGNKMGI 719

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
             +     +  I  +     +N     +++S   LTV A DG   + SD   + I+V DV
Sbjct: 720 FRIDSDSGEITIAKRAPVDMSNSTNGGDSIS---LTVQASDG---TFSDKALISITVRDV 773

Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634
           N+N P F   LYTA+I E + VGT V ++ ATDAD G+N  + Y +      +  F ++ 
Sbjct: 774 NNNAPAFAHDLYTASIPELSPVGTVVEELTATDADSGINAELVYRIQKGGFND--FAVNE 831

Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694
            SG +  ++ LD +   T+ ++ +A D G+P  + T  + I +E+ ND PP F       
Sbjct: 832 TSGAVFVSRKLDYDQRNTYHVEVIAFDKGSPSLTGTTTLMINVENSNDKPPYFSPGTQRA 891

Query: 695 YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDL 754
            ++E++ IGT    ++A DPD      ++++I     S   +   R G    +  T    
Sbjct: 892 EVTEDTAIGTVFTTLKAIDPDSTDPEALNFAI-----SEPITAIDRNGQRVNDSTTAFKD 946

Query: 755 DYESPRKKYEL-VIRAASPPLWNDVRVEILVTDVNDNAPVMK 795
            +   RK  ++ V+++    +   V + ++VTD   +AP ++
Sbjct: 947 FFAVDRKTGQVSVVKSLDRDIAATVSLTLVVTDT--SAPTLQ 986



 Score = 94.3 bits (224), Expect = 4e-17
 Identities = 133/503 (26%), Positives = 212/503 (42%), Gaps = 42/503 (8%)

Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434
           L E  P GT V TL   D  E + + Y   G     +F +  + G  ++T+A+PLD ++ 
Sbjct: 396 LNEATPVGTKVFTLKGHDP-EGSPVKY---GVQLTDKFVVDQRTG--VMTLAKPLDREEA 449

Query: 435 RRYVLTVSATDS---GGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVL 489
                 V+  DS   G + +   V+ ++   D N+  P F   PY A V ED+P GTT+L
Sbjct: 450 DTIRFRVTLEDSVPQGQQPNIVGVEAHVIVLDENDNPPQFLGVPYEAVVAEDSPPGTTIL 509

Query: 490 -VVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFVINPQT--GAITTNKLLDRETMS 545
             +  TD D +G N Q+T     +  +            +  T  GA+   + LD +   
Sbjct: 510 PAIRVTDPDLLGENIQVTCIPQPQFPDACTKFGIVNIERSQDTYIGALVLQQPLDYKERP 569

Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
            Y L + A DG   S S++T VEI V D+ ++ P F   L T  + ED  +GT V  V A
Sbjct: 570 FYQLLLQASDG---SNSNSTGVEIKVTDIQNSPPEFLDSL-TGVVKEDDPIGTLVMTVKA 625

Query: 606 TDADVGLNGRIHYEL---DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
            D D G+  +I YEL   +    + G       S  +    A D      H      ID 
Sbjct: 626 RDGDRGMPRKIVYELVTSESATDDNGKGQTTSVSLRLSLADANDSPPKFQHKKYRAVIDE 685

Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
           G       + V  +  D        ++  +T+ I E + +G    +  + +      A V
Sbjct: 686 GAEKFEPPLRVQARDRD--------KTSKITYSIVEGNKMGIFRIDSDSGEITIAKRAPV 737

Query: 723 HYS-IKGGDDSNSFSLETRQG--SDKAEL-VTMVDLDYESPRKKYELVIRAASPPL--WN 776
             S    G DS S +++   G  SDKA + +T+ D++  +P   ++L   A+ P L    
Sbjct: 738 DMSNSTNGGDSISLTVQASDGTFSDKALISITVRDVNNNAPAFAHDL-YTASIPELSPVG 796

Query: 777 DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNN 836
            V  E+  TD +        ++I    + D F V            V+ KL Y   +  +
Sbjct: 797 TVVEELTATDADSGINAELVYRIQKGGFND-FAVNETSGA----VFVSRKLDYDQRNTYH 851

Query: 837 ANLILLNETTGSMTLSPQLNTNV 859
             +I  ++ + S+T +  L  NV
Sbjct: 852 VEVIAFDKGSPSLTGTTTLMINV 874



 Score = 86.6 bits (205), Expect = 9e-15
 Identities = 68/242 (28%), Positives = 107/242 (44%), Gaps = 15/242 (6%)

Query: 69  TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
           TL   D           + D F +D R+G +     LDRE+       V   D       
Sbjct: 408 TLKGHDPEGSPVKYGVQLTDKFVVDQRTGVMTLAKPLDREEADTIRFRVTLEDSVPQGQQ 467

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSAI 187
                   HV ++D+NDN PQF    Y   V ED S     ++  I+ TD D +G N  +
Sbjct: 468 PNIVGVEAHVIVLDENDNPPQFLGVPYEAVVAED-SPPGTTILPAIRVTDPDLLGENIQV 526

Query: 188 R---------YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238
                          G   ++ S D+  G + L + LDY++   Y+L+++A DG   S S
Sbjct: 527 TCIPQPQFPDACTKFGIVNIERSQDTYIGALVLQQPLDYKERPFYQLLLQASDG---SNS 583

Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
           N+T + I + D+ ++ P F  SL    V E+ PIG  ++ V+A D D G+  ++ Y +  
Sbjct: 584 NSTGVEIKVTDIQNSPPEFLDSL-TGVVKEDDPIGTLVMTVKARDGDRGMPRKIVYELVT 642

Query: 299 KD 300
            +
Sbjct: 643 SE 644



 Score = 83.0 bits (196), Expect = 1e-13
 Identities = 74/258 (28%), Positives = 115/258 (44%), Gaps = 26/258 (10%)

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
           +++E  P+G  +  ++ +D  EG   +    +TDK           +D R+G +  +  L
Sbjct: 395 TLNEATPVGTKVFTLKGHDP-EGSPVKYGVQLTDK---------FVVDQRTGVMTLAKPL 444

Query: 325 DRETQAKYQLLVTATDG---GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381
           DRE     +  VT  D    G  P                    F+   YE  +AED PP
Sbjct: 445 DREEADTIRFRVTLEDSVPQGQQPNIVGVEAHVIVLDENDNPPQFLGVPYEAVVAEDSPP 504

Query: 382 GTPVV-TLTATDAD---EDNRL----HYEITGGNTR-GRFSITSQNGR--GLITVAQPLD 430
           GT ++  +  TD D   E+ ++      +     T+ G  +I        G + + QPLD
Sbjct: 505 GTTILPAIRVTDPDLLGENIQVTCIPQPQFPDACTKFGIVNIERSQDTYIGALVLQQPLD 564

Query: 431 FKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
           +K+   Y L + A+D G  S++  V+I +TD  N  P F ++  T  V ED PIGT V+ 
Sbjct: 565 YKERPFYQLLLQASD-GSNSNSTGVEIKVTDIQNSPPEFLDS-LTGVVKEDDPIGTLVMT 622

Query: 491 VSATDSDVGINAQITYSL 508
           V A D D G+  +I Y L
Sbjct: 623 VKARDGDRGMPRKIVYEL 640



 Score = 72.1 bits (169), Expect = 2e-10
 Identities = 87/298 (29%), Positives = 128/298 (42%), Gaps = 26/298 (8%)

Query: 556 GGVPSLSDTTDVEISVVDVNDNEP-VFKQQLYTAN--IMEDALVGTSVSQVGATDADVGL 612
           G  P L+    +   V   N NEP +F    Y     + E   VGT V  +   D +   
Sbjct: 359 GRSPLLAALLLLATCVAGNNVNEPPIFDGSGYPMGWTLNEATPVGTKVFTLKGHDPE--- 415

Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG---GTPPQSS 669
              + Y +   D+    FV+D  +GV+   K LDRE   T   +    D    G  P   
Sbjct: 416 GSPVKYGVQLTDK----FVVDQRTGVMTLAKPLDREEADTIRFRVTLEDSVPQGQQPNIV 471

Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI-GEIRAHDPD-EGPNAVVHY--S 725
            V  H+ + D ND+PP F        ++E+SP GTTI   IR  DPD  G N  V     
Sbjct: 472 GVEAHVIVLDENDNPPQFLGVPYEAVVAEDSPPGTTILPAIRVTDPDLLGENIQVTCIPQ 531

Query: 726 IKGGDDSNSF---SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEI 782
            +  D    F   ++E  Q +    LV    LDY+  R  Y+L+++A+     N   VEI
Sbjct: 532 PQFPDACTKFGIVNIERSQDTYIGALVLQQPLDYKE-RPFYQLLLQASDGSNSNSTGVEI 590

Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDAD--VTDKLQYRILSGNNA 837
            VTD+ ++ P   D   +    K+  P+G     V A D D  +  K+ Y +++  +A
Sbjct: 591 KVTDIQNSPPEFLD--SLTGVVKEDDPIGTLVMTVKARDGDRGMPRKIVYELVTSESA 646



 Score = 52.0 bits (119), Expect = 2e-04
 Identities = 50/188 (26%), Positives = 87/188 (46%), Gaps = 21/188 (11%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVL-TLKATDQD-IGKNAEVEYTIEL 64
           +   + VLD ND+ P F    YEA V E +  GTT+L  ++ TD D +G+N +V      
Sbjct: 473 VEAHVIVLDENDNPPQFLGVPYEAVVAEDSPPGTTILPAIRVTDPDLLGENIQV------ 526

Query: 65  VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS 124
               T  P+            V      D   GAL+ +  LD ++   Y +L++A+D ++
Sbjct: 527 ----TCIPQPQFPDACTKFGIVNIERSQDTYIGALVLQQPLDYKERPFYQLLLQASDGSN 582

Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184
                 S++  + + + D  ++ P+F + + T  V ED  +    ++  +KA D D G  
Sbjct: 583 ------SNSTGVEIKVTDIQNSPPEFLD-SLTGVVKEDDPI--GTLVMTVKARDGDRGMP 633

Query: 185 SAIRYAII 192
             I Y ++
Sbjct: 634 RKIVYELV 641



 Score = 44.8 bits (101), Expect = 0.035
 Identities = 39/147 (26%), Positives = 68/147 (46%), Gaps = 16/147 (10%)

Query: 753 DLDYESPRK-KYELVIRAASPP-----LWNDVRVEILVTDVNDNAPVM--KDFQIIFNNY 804
           D D   PRK  YELV   ++           V + + + D ND+ P    K ++ + +  
Sbjct: 627 DGDRGMPRKIVYELVTSESATDDNGKGQTTSVSLRLSLADANDSPPKFQHKKYRAVIDEG 686

Query: 805 KDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQL------NTN 858
            + F   P  RV A D D T K+ Y I+ GN   +  ++  +G +T++ +       +TN
Sbjct: 687 AEKFE--PPLRVQARDRDKTSKITYSIVEGNKMGIFRIDSDSGEITIAKRAPVDMSNSTN 744

Query: 859 VPKLATMEVSVTDGVNEIKAMMQLSVR 885
                ++ V  +DG    KA++ ++VR
Sbjct: 745 GGDSISLTVQASDGTFSDKALISITVR 771



 Score = 41.5 bits (93), Expect = 0.32
 Identities = 19/56 (33%), Positives = 30/56 (53%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
            ++  I +LD ND+ P FE   Y A V   A+    V  + A+D D+G N  ++Y +
Sbjct: 1542 VNVTIKILDENDNPPAFERSAYFAGVNSMANINELVTKVTASDADLGDNGTLQYYV 1597


>UniRef50_Q08174 Cluster: Protocadherin-1 precursor; n=52;
           Euteleostomi|Rep: Protocadherin-1 precursor - Homo
           sapiens (Human)
          Length = 1026

 Score =  294 bits (721), Expect = 3e-77
 Identities = 209/735 (28%), Positives = 347/735 (47%), Gaps = 53/735 (7%)

Query: 91  RIDGRSGALLT-RASLDREKVARYT--------VL---VKATDQASPVSDRLSSTATIHV 138
           R+DG++G + T   S+DRE +            +L   V  TD     S RL       +
Sbjct: 78  RVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNASPRLLEG---QI 134

Query: 139 NIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQM 198
            + D NDN P F+    T+++ E+ ++    +     A+D D G N    Y +     Q+
Sbjct: 135 EVQDINDNTPNFASPVITLAIPENTNI--GSLFPIPLASDRDAGPNGVASYEL-----QV 187

Query: 199 QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY 258
               +     + ++  LD E+  SY L I+ QDGGSP R+ +  L + + D NDNAP+F 
Sbjct: 188 AEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRATSALLRVTVLDTNDNAPKFE 247

Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV 318
              ++  +SEN PIG+S+++V+A D+D+G NAE+ YT         V   + +D  +G +
Sbjct: 248 RPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEV--VRRLLRLDRNTGLI 305

Query: 319 YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF-MPG-------Q 370
              G +DRE  +  +  V A D G  P+SA A                 + G        
Sbjct: 306 TVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQD 365

Query: 371 YEVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQNG-----RGLIT 424
               ++ED    T V  +  +D DE +N     +  G+   +    S+ G     +  + 
Sbjct: 366 GMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQ 425

Query: 425 VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
              PLD+++ + Y + + A DSG    S T  +++ + D N+ APVF  +    +  E+ 
Sbjct: 426 TTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENN 485

Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
             G  +  ++A+D+D G NA++ YSL  E + + +      F I+P+TG I     LDRE
Sbjct: 486 KPGEVIAEITASDADSGSNAELVYSLEPEPAAKGL------FTISPETGEIQVKTSLDRE 539

Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
               Y L V A D G PSL  T  V ++V+D NDN+P F    Y  ++ME+    + V  
Sbjct: 540 QRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGM 599

Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
           V   D D G N ++   +   +++ G FVI   +G I ++ + DRE  +T+  +  A+DG
Sbjct: 600 VTVIDGDKGENAQVQLSV---EQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDG 656

Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY--ISENSPIGTTIGEIRAHDPDEGPNA 720
           G PP+S+ V V I + D ND+ P   +   T +  ++  + +G T+ ++ A D D G NA
Sbjct: 657 GVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNA 716

Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRV 780
            + YSI GG+    F + +  G+    L   ++  +    +    V     PP +    V
Sbjct: 717 ELIYSIAGGNPYGLFQIGSHSGA--ITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALV 774

Query: 781 EILVTDVNDNAPVMK 795
            + V +   N  +++
Sbjct: 775 HLYVNETLANRTLLE 789



 Score =  247 bits (605), Expect = 3e-63
 Identities = 197/695 (28%), Positives = 314/695 (45%), Gaps = 60/695 (8%)

Query: 4   PFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIE 63
           P  +  QI V D ND++P F       ++ E  + G+      A+D+D G N    Y ++
Sbjct: 127 PRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQ 186

Query: 64  LVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQA 123
           +        ED                  + +   L+   +LDRE+   Y + +K  D  
Sbjct: 187 VA-------EDQ-----------------EEKQPQLIVMGNLDRERWDSYDLTIKVQDGG 222

Query: 124 SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183
           SP     +++A + V ++D NDN P+F   +Y   + E+  +  +  + ++KA D+D GA
Sbjct: 223 SPPR---ATSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHS--VIQVKANDSDQGA 277

Query: 184 NSAIRYAIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
           N+ I Y        ++    +D  +G +++   +D E + + R  + A+D G+  +S   
Sbjct: 278 NAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARA 337

Query: 242 QLLINIRDVNDNAPRFYTS-----LFQE---SVSENVPIGYSIVRVQAYDADEGVNAELT 293
           Q+++ ++D+NDNAP            Q+   ++SE+V    ++  VQ  D DEG NA +T
Sbjct: 338 QVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVT 397

Query: 294 YTMT-DKDYTGNVDLPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
             +  D  +          D +  + + T+  LD E    Y + + A D G+PP S+T +
Sbjct: 398 CVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNS 457

Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNT- 408
                         F     EV   E+  PG  +  +TA+DAD  +   L Y +      
Sbjct: 458 LKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAA 517

Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYA 466
           +G F+I+ + G   I V   LD +Q   Y L V A D G  S   TA V +N+ D N+  
Sbjct: 518 KGLFTISPETGE--IQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDND 575

Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
           P F  + Y  SV E+ P  + V +V+  D D G NAQ+  S+  +         +  FVI
Sbjct: 576 PKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQD---------NGDFVI 626

Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586
              TG I ++   DRE  S Y   + A DGGVP  S    V I+V+D NDN P       
Sbjct: 627 QNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSN 686

Query: 587 TAN--IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA 644
           T++  +     +G +VSQV A D D G+N  + Y +       G F I   SG I   K 
Sbjct: 687 TSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSI-AGGNPYGLFQIGSHSGAITLEKE 745

Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679
           ++R     H L     D G PP+  T +VH+ + +
Sbjct: 746 IERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNE 780



 Score =  247 bits (604), Expect = 4e-63
 Identities = 183/645 (28%), Positives = 286/645 (44%), Gaps = 34/645 (5%)

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           I ++D+NDN P F + +   ++ EN  IG       A D D G N   +Y +   +    
Sbjct: 134 IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQVAEDQ-- 191

Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
                  + +   +   G LDRE    Y L +   DGG PPR+ +A              
Sbjct: 192 -------EEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRATSALLRVTVLDTNDNAP 244

Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG--RFSITSQNGRGL 422
            F    YE EL+E+ P G  V+ + A D+D+      E T        R  +      GL
Sbjct: 245 KFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGL 304

Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFE--------NA 472
           ITV  P+D +       +V A D G    +A  Q+ +T  D N+ AP  E        + 
Sbjct: 305 ITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQ 364

Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
              A++ ED    T V +V  +D D G NA +T  ++ ++  + +    +    + +   
Sbjct: 365 DGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQ-LRQASETGSDSKKKYF 423

Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592
           + T   LD E +  Y + + A D G P LS T  +++ VVDVNDN PVF Q +      E
Sbjct: 424 LQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPE 483

Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652
           +   G  ++++ A+DAD G N  + Y L+P+   +G F I P +G I+   +LDRE   +
Sbjct: 484 NNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRES 543

Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
           ++LK VA D G+P    T  V + + D ND+ P F      F + EN P  + +G +   
Sbjct: 544 YELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVI 603

Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP 772
           D D+G NA V  S++   D+  F ++   G+  + L    D + +S        +    P
Sbjct: 604 DGDKGENAQVQLSVE--QDNGDFVIQNGTGTILSSL--SFDREQQSTYTFQLKAVDGGVP 659

Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA------YDADVTDK 826
           P    V V I V D NDNAP +        ++K   P    G   +      +D+ V  +
Sbjct: 660 PRSAYVGVTINVLDENDNAPYIT--APSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAE 717

Query: 827 LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
           L Y I  GN   L  +   +G++TL  ++      L  + V V+D
Sbjct: 718 LIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSD 762



 Score =  234 bits (573), Expect = 2e-59
 Identities = 195/648 (30%), Positives = 295/648 (45%), Gaps = 70/648 (10%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ VLD ND++P FE   YEA + E +  G +V+ +KA D D G NAE+EYT        
Sbjct: 233 RVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQA---- 288

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             PE            V+ + R+D  +G +  +  +DRE ++     V A D+ +   + 
Sbjct: 289 --PE-----------VVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGT---NP 332

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED----IS--VTDNPVIAKIKATDADVGA 183
            S+ A + V + D NDN P    +   +   +D    IS  V +   +A ++ +D D G 
Sbjct: 333 KSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGE 392

Query: 184 NSAIRYAIIGGNTQMQFSIDSLSGDVSLVK-------TLDYEQVRSYRLVIRAQDGGSPS 236
           N+A+   ++ G+   Q    S +G  S  K        LDYE+V+ Y + I A D G+P 
Sbjct: 393 NAAVT-CVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPP 451

Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
            S+T  L + + DVNDNAP F  S+ + +  EN   G  I  + A DAD G NAEL Y++
Sbjct: 452 LSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSL 511

Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
             +     +    TI P +G +     LDRE +  Y+L V A D G P    TAT     
Sbjct: 512 EPEPAAKGL---FTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNV 568

Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITS 416
                    FM   Y   + E+ P  +PV  +T  D D+      +++     G F I  
Sbjct: 569 LDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVI-- 626

Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPY 474
           QNG G I  +   D +Q+  Y   + A D G   RS    V IN+ D N+ AP +  AP 
Sbjct: 627 QNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAP-YITAPS 685

Query: 475 TAS---VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
             S   +     +G TV  V+A D D G+NA++ YS+       A  +    F I   +G
Sbjct: 686 NTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSI-------AGGNPYGLFQIGSHSG 738

Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
           AIT  K ++R     + L V   D G P    T  V + V     NE +  + L      
Sbjct: 739 AITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYV-----NETLANRTLL----- 788

Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639
            + L+G S+     T  D+ + G   YE   + ++ G+ +    +GV+
Sbjct: 789 -ETLLGHSLD----TPLDIDIAGDPEYE---RSKQRGNILFGVVAGVV 828



 Score =  182 bits (444), Expect = 1e-43
 Identities = 153/507 (30%), Positives = 239/507 (47%), Gaps = 40/507 (7%)

Query: 429 LDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
           LD ++   Y LT+   D G   R+ +A++++ + D N+ AP FE   Y A + E++PIG 
Sbjct: 204 LDRERWDSYDLTIKVQDGGSPPRATSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGH 263

Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
           +V+ V A DSD G NA+I Y+     + E V    +   ++  TG IT    +DRE +S 
Sbjct: 264 SVIQVKANDSDQGANAEIEYTFHQ--APEVVR---RLLRLDRNTGLITVQGPVDREDLST 318

Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ---LYT-----ANIMEDALVGT 598
              +V A+D G    S    V ++V D+NDN P  + +   L T     ANI ED    T
Sbjct: 319 LRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEET 378

Query: 599 SVSQVGATDADVGLN--------GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650
           +V+ V  +D D G N        G + ++L     E GS         ++T   LD E V
Sbjct: 379 AVALVQVSDRDEGENAAVTCVVAGDVPFQLRQAS-ETGSD--SKKKYFLQTTTPLDYEKV 435

Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710
             + ++ VA+D G PP SST  + +++ D+ND+ PVF          EN+  G  I EI 
Sbjct: 436 KDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEIT 495

Query: 711 AHDPDEGPNAVVHYSIKGGDDSNS-FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
           A D D G NA + YS++    +   F++    G    E+     LD E  R+ YEL + A
Sbjct: 496 ASDADSGSNAELVYSLEPEPAAKGLFTISPETG----EIQVKTSLDREQ-RESYELKVVA 550

Query: 770 A---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK 826
           A   SP L     V + V D NDN P        F+  ++   + P G V   D D  + 
Sbjct: 551 ADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGEN 610

Query: 827 LQYRI-LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSV 884
            Q ++ +  +N + ++ N  TG++  S   +       T ++   D GV    A + +++
Sbjct: 611 AQVQLSVEQDNGDFVIQN-GTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTI 669

Query: 885 RLITEEMLLNSITVRLNDMTAEQFLSP 911
            ++ E      IT   N  T+ + L+P
Sbjct: 670 NVLDENDNAPYITAPSN--TSHKLLTP 694



 Score =  148 bits (359), Expect = 2e-33
 Identities = 123/417 (29%), Positives = 191/417 (45%), Gaps = 41/417 (9%)

Query: 456 QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515
           QI + D N+  P F +   T ++ E+  IG+   +  A+D D G N   +Y L  +++ +
Sbjct: 133 QIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYEL--QVAED 190

Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575
                 Q  V+            LDRE    Y LT+  +DGG P  + +  + ++V+D N
Sbjct: 191 QEEKQPQLIVMGN----------LDRERWDSYDLTIKVQDGGSPPRATSALLRVTVLDTN 240

Query: 576 DNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV-IDP 634
           DN P F++  Y A + E++ +G SV QV A D+D G N  I Y            + +D 
Sbjct: 241 DNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDR 300

Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694
            +G+I     +DRE ++T     +A D GT P+S+   V + ++D+ND+ P  E   +  
Sbjct: 301 NTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGL 360

Query: 695 Y--------ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD-- 744
                    ISE+    T +  ++  D DEG NA V   +  GD        +  GSD  
Sbjct: 361 VTHQDGMANISEDVAEETAVALVQVSDRDEGENAAV-TCVVAGDVPFQLRQASETGSDSK 419

Query: 745 -KAELVTMVDLDYESPRK-KYELV-IRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801
            K  L T   LDYE  +    E+V + + +PPL +   +++ V DVNDNAPV        
Sbjct: 420 KKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEV 479

Query: 802 NNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNE----TTGSMTLSPQ 854
              ++  P      + A DAD          SG+NA L+   E      G  T+SP+
Sbjct: 480 AFPENNKPGEVIAEITASDAD----------SGSNAELVYSLEPEPAAKGLFTISPE 526


>UniRef50_A7S9Y3 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 868

 Score =  293 bits (720), Expect = 3e-77
 Identities = 191/509 (37%), Positives = 271/509 (53%), Gaps = 27/509 (5%)

Query: 140 IIDDNDNYPQF-SEKTYTVSVDEDISVTDNPV-IAKIKATDADVGANSAIRYAIIGGNTQ 197
           I D N++ PQF S  +YT  + ED   T   V IA + ATDAD G++ AI +AII GN +
Sbjct: 377 ISDVNEHTPQFTSGGSYTAVIAEDAPDTAIGVTIATVAATDADHGSDGAISFAIIAGNEE 436

Query: 198 MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF 257
            +F ID+ SG + L + LD E   SY L + A+D GSP++S+   + + + DVNDNAP  
Sbjct: 437 DKFLIDTTSGVIELKRPLDRESTGSYILTVLARDHGSPNKSSNASVDVTVVDVNDNAPNC 496

Query: 258 YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317
             +     V+EN  +G +++ ++  D DEG N++LTY +T    TG VD   TID  SG 
Sbjct: 497 SVTAHVVEVAENASVGSTVLELRCEDVDEGANSQLTYNIT----TG-VD--FTIDKSSGV 549

Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPP---RSATATXXXXXXXXXXXXXXFMPGQYEVE 374
           V     LDRET+  Y+L +T  D G+     R+A                 F    Y   
Sbjct: 550 VAVGSSLDRETRDLYELNITVRDRGNTEQERRAAVMQLTIEVTDENDNPPVFTQEIYTTT 609

Query: 375 LAEDEPPGTPVVTLTATDADED-NRLH-YEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432
           + E+   G  V  +  TD D   N  H Y ITGG+  G+FSI      G+IT    LD++
Sbjct: 610 IPENMASGASVARVATTDRDIGINANHTYSITGGDGLGKFSIVQST--GVITALPGLDYE 667

Query: 433 QERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
            +  Y L+++A D G       A V+I ++D N+  PVF    Y  S+ E    GT V+ 
Sbjct: 668 TKYTYYLSITARDRGSPQLYAVAGVRIFLSDTNDNKPVFSPTLYLTSISEATSAGTDVIP 727

Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550
           V ATD D GINA+ITYS+   +  +A      QF +N  TG I T   LDRE ++ Y L 
Sbjct: 728 VHATDVDTGINAEITYSI---VGGDA----KNQFSVN-STGMIRTIATLDREDIASYTLL 779

Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610
           V A D GVP  ++T  V ++++DVNDN  VF Q  ++A ++EDA VG     + A+DAD 
Sbjct: 780 VQASDRGVPPQTETVHVTVTILDVNDNAAVFSQSAFSARVLEDAPVGFRFMNISASDADS 839

Query: 611 GLNGRIHYELDPKDREEGSFVIDPASGVI 639
           G N R+ Y +      +    I+ A+G +
Sbjct: 840 GDNARLTYSIQ-SGNTDNVVAIESATGAL 867



 Score =  260 bits (638), Expect = 3e-67
 Identities = 176/522 (33%), Positives = 256/522 (49%), Gaps = 31/522 (5%)

Query: 234 SPSRSNTTQLLINIRDVNDNAPRF-----YTSLFQESVSENVPIGYSIVRVQAYDADEGV 288
           S S +N    +  I DVN++ P+F     YT++  E   +   IG +I  V A DAD G 
Sbjct: 364 SDSGTNGQFKMAIISDVNEHTPQFTSGGSYTAVIAEDAPDTA-IGVTIATVAATDADHGS 422

Query: 289 NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348
           +  +++ +      GN +    ID  SG +     LDRE+   Y L V A D G P +S+
Sbjct: 423 DGAISFAII----AGNEEDKFLIDTTSGVIELKRPLDRESTGSYILTVLARDHGSPNKSS 478

Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGG 406
            A+                   + VE+AE+   G+ V+ L   D DE  +++L Y IT G
Sbjct: 479 NASVDVTVVDVNDNAPNCSVTAHVVEVAENASVGSTVLELRCEDVDEGANSQLTYNITTG 538

Query: 407 NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG-----RSDTAMVQINITD 461
                   T     G++ V   LD +    Y L ++  D G      R+    + I +TD
Sbjct: 539 -----VDFTIDKSSGVVAVGSSLDRETRDLYELNITVRDRGNTEQERRAAVMQLTIEVTD 593

Query: 462 ANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521
            N+  PVF    YT ++ E+   G +V  V+ TD D+GINA  TYS++     + +    
Sbjct: 594 ENDNPPVFTQEIYTTTIPENMASGASVARVATTDRDIGINANHTYSITG---GDGLG--- 647

Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581
            +F I   TG IT    LD ET   Y L++TARD G P L     V I + D NDN+PVF
Sbjct: 648 -KFSIVQSTGVITALPGLDYETKYTYYLSITARDRGSPQLYAVAGVRIFLSDTNDNKPVF 706

Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641
              LY  +I E    GT V  V ATD D G+N  I Y +   D +   F ++ ++G+IRT
Sbjct: 707 SPTLYLTSISEATSAGTDVIPVHATDVDTGINAEITYSIVGGDAKN-QFSVN-STGMIRT 764

Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701
              LDRE +A++ L   A D G PPQ+ TV V + I D+ND+  VF     +  + E++P
Sbjct: 765 IATLDREDIASYTLLVQASDRGVPPQTETVHVTVTILDVNDNAAVFSQSAFSARVLEDAP 824

Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
           +G     I A D D G NA + YSI+ G+  N  ++E+  G+
Sbjct: 825 VGFRFMNISASDADSGDNARLTYSIQSGNTDNVVAIESATGA 866



 Score =  249 bits (609), Expect = 1e-63
 Identities = 172/497 (34%), Positives = 243/497 (48%), Gaps = 36/497 (7%)

Query: 369 GQYEVELAEDEPP---GTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLI 423
           G Y   +AED P    G  + T+ ATDAD   D  + + I  GN   +F I + +G  +I
Sbjct: 391 GSYTAVIAEDAPDTAIGVTIATVAATDADHGSDGAISFAIIAGNEEDKFLIDTTSG--VI 448

Query: 424 TVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFED 481
            + +PLD +    Y+LTV A D G   +S  A V + + D N+ AP      +   V E+
Sbjct: 449 ELKRPLDRESTGSYILTVLARDHGSPNKSSNASVDVTVVDVNDNAPNCSVTAHVVEVAEN 508

Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
           A +G+TVL +   D D G N+Q+TY++++ +           F I+  +G +     LDR
Sbjct: 509 ASVGSTVLELRCEDVDEGANSQLTYNITTGVD----------FTIDKSSGVVAVGSSLDR 558

Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDV---EISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
           ET   Y L +T RD G         V    I V D NDN PVF Q++YT  I E+   G 
Sbjct: 559 ETRDLYELNITVRDRGNTEQERRAAVMQLTIEVTDENDNPPVFTQEIYTTTIPENMASGA 618

Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
           SV++V  TD D+G+N    Y +   D   G F I  ++GVI     LD E+  T+ L   
Sbjct: 619 SVARVATTDRDIGINANHTYSITGGDGL-GKFSIVQSTGVITALPGLDYETKYTYYLSIT 677

Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
           A D G+P   +   V I + D ND+ PVF        ISE +  GT +  + A D D G 
Sbjct: 678 ARDRGSPQLYAVAGVRIFLSDTNDNKPVFSPTLYLTSISEATSAGTDVIPVHATDVDTGI 737

Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLW 775
           NA + YSI GGD  N FS+ +        + T+  LD E     Y L+++A+    PP  
Sbjct: 738 NAEITYSIVGGDAKNQFSVNST-----GMIRTIATLDREDIAS-YTLLVQASDRGVPPQT 791

Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTD--KLQYRIL 832
             V V + + DVNDNA V           +D  PVG  F  + A DAD  D  +L Y I 
Sbjct: 792 ETVHVTVTILDVNDNAAVFSQSAFSARVLEDA-PVGFRFMNISASDADSGDNARLTYSIQ 850

Query: 833 SGNNANLILLNETTGSM 849
           SGN  N++ +   TG++
Sbjct: 851 SGNTDNVVAIESATGAL 867



 Score =  239 bits (586), Expect = 6e-61
 Identities = 169/517 (32%), Positives = 247/517 (47%), Gaps = 45/517 (8%)

Query: 13  VLDCNDHSPVFEMQ-QYEASVREGASS---GTTVLTLKATDQDIGKNAEVEYTIELVTAD 68
           + D N+H+P F     Y A + E A     G T+ T+ ATD D G +  + + I      
Sbjct: 377 ISDVNEHTPQFTSGGSYTAVIAEDAPDTAIGVTIATVAATDADHGSDGAISFAI------ 430

Query: 69  TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
                             +D F ID  SG +  +  LDRE    Y + V A D  SP   
Sbjct: 431 -------------IAGNEEDKFLIDTTSGVIELKRPLDRESTGSYILTVLARDHGSP--- 474

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             SS A++ V ++D NDN P  S   + V V E+ SV     + +++  D D GANS + 
Sbjct: 475 NKSSNASVDVTVVDVNDNAPNCSVTAHVVEVAENASV--GSTVLELRCEDVDEGANSQLT 532

Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS---RSNTTQLLI 245
           Y I    T + F+ID  SG V++  +LD E    Y L I  +D G+     R+   QL I
Sbjct: 533 YNI---TTGVDFTIDKSSGVVAVGSSLDRETRDLYELNITVRDRGNTEQERRAAVMQLTI 589

Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
            + D NDN P F   ++  ++ EN+  G S+ RV   D D G+NA  TY++T  D  G  
Sbjct: 590 EVTDENDNPPVFTQEIYTTTIPENMASGASVARVATTDRDIGINANHTYSITGGDGLGK- 648

Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
               +I   +G +     LD ET+  Y L +TA D G P   A A               
Sbjct: 649 ---FSIVQSTGVITALPGLDYETKYTYYLSITARDRGSPQLYAVAGVRIFLSDTNDNKPV 705

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLI 423
           F P  Y   ++E    GT V+ + ATD D   +  + Y I GG+ + +FS+   N  G+I
Sbjct: 706 FSPTLYLTSISEATSAGTDVIPVHATDVDTGINAEITYSIVGGDAKNQFSV---NSTGMI 762

Query: 424 TVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
                LD +    Y L V A+D G   +++T  V + I D N+ A VF  + ++A V ED
Sbjct: 763 RTIATLDREDIASYTLLVQASDRGVPPQTETVHVTVTILDVNDNAAVFSQSAFSARVLED 822

Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518
           AP+G   + +SA+D+D G NA++TYS+ S  ++  VA
Sbjct: 823 APVGFRFMNISASDADSGDNARLTYSIQSGNTDNVVA 859



 Score =  202 bits (493), Expect = 1e-49
 Identities = 131/411 (31%), Positives = 201/411 (48%), Gaps = 31/411 (7%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + V+D ND++P   +  +   V E AS G+TVL L+  D D G N+++ Y I      T 
Sbjct: 484 VTVVDVNDNAPNCSVTAHVVEVAENASVGSTVLELRCEDVDEGANSQLTYNI------TT 537

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             +                F ID  SG +   +SLDRE    Y + +   D+ +   +R 
Sbjct: 538 GVD----------------FTIDKSSGVVAVGSSLDRETRDLYELNITVRDRGNTEQERR 581

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           ++   + + + D+NDN P F+++ YT ++ E+++      +A++  TD D+G N+   Y+
Sbjct: 582 AAVMQLTIEVTDENDNPPVFTQEIYTTTIPENMA--SGASVARVATTDRDIGINANHTYS 639

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
           I GG+   +FSI   +G ++ +  LDYE   +Y L I A+D GSP       + I + D 
Sbjct: 640 ITGGDGLGKFSIVQSTGVITALPGLDYETKYTYYLSITARDRGSPQLYAVAGVRIFLSDT 699

Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
           NDN P F  +L+  S+SE    G  ++ V A D D G+NAE+TY++   D      +  T
Sbjct: 700 NDNKPVFSPTLYLTSISEATSAGTDVIPVHATDVDTGINAEITYSIVGGDAKNQFSVNST 759

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
                G + T   LDRE  A Y LLV A+D G PP++ T                F    
Sbjct: 760 -----GMIRTIATLDREDIASYTLLVQASDRGVPPQTETVHVTVTILDVNDNAAVFSQSA 814

Query: 371 YEVELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRGRFSITSQNG 419
           +   + ED P G   + ++A+DAD  DN RL Y I  GNT    +I S  G
Sbjct: 815 FSARVLEDAPVGFRFMNISASDADSGDNARLTYSIQSGNTDNVVAIESATG 865



 Score =  177 bits (432), Expect = 3e-42
 Identities = 123/401 (30%), Positives = 197/401 (49%), Gaps = 37/401 (9%)

Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ-YEVELAEDEPPG 382
           L+ ET  +Y L + A+DGG P +++T                F+P   YE+ LAED   G
Sbjct: 1   LNYETTMRYTLSIQASDGGTPGKASTTLAVIDVQGVNEYTPSFIPNNTYELSLAEDLSVG 60

Query: 383 TPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
             V+ +TA+DAD  ++        +  G F++++    G++++A  LD++  R Y L +S
Sbjct: 61  HDVILVTASDADAGSQGEDAFIFLSVTGNFNVSTA---GVVSLATALDYESTRLYSLVLS 117

Query: 443 ATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
            TDSG  + +  + + +T    N ++PVF +    A    +  +GT++  +  TDSD+G 
Sbjct: 118 VTDSGLSTKSTQISVKVTVIAVNEFSPVFTSGGTYAVT--NTTVGTSITQLQCTDSDLGT 175

Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560
           NA ++YS++    N         F ++  +G +TT K LD ET   Y +T+ ARD     
Sbjct: 176 NAALSYSITDGDPNSV-------FTVS-SSGELTTVKQLDYETTQSYAITIQARDTSASQ 227

Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620
           L   + V++ V  +N+  P F Q  Y   I E   +GT+              G + Y +
Sbjct: 228 LMAVSHVDVIVQALNEYTPSFSQSEYNVTISEATPIGTT--------------GELTYSM 273

Query: 621 DPKDREEGS-FVIDPASGVIRTNKALDRESVATHDLKAVAIDG-GTPPQSSTVIVHIKIE 678
                  GS F ID  SGVI   + LD E+V ++ L   A DG  + P+SS V V + ++
Sbjct: 274 P-----SGSPFYIDSLSGVITLKQGLDYEAVTSYVLLVTATDGDASSPKSSMVNVTVTVK 328

Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
           D ND+ P F     +  I EN+ +GT+I  +   D D G N
Sbjct: 329 DENDNEPTFTPAVYSVVIPENTTVGTSILSLTCTDSDSGTN 369



 Score =  171 bits (415), Expect = 3e-40
 Identities = 123/408 (30%), Positives = 197/408 (48%), Gaps = 44/408 (10%)

Query: 215 LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY-TSLFQESVSENVPIG 273
           L+YE    Y L I+A DGG+P +++TT  +I+++ VN+  P F   + ++ S++E++ +G
Sbjct: 1   LNYETTMRYTLSIQASDGGTPGKASTTLAVIDVQGVNEYTPSFIPNNTYELSLAEDLSVG 60

Query: 274 YSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQ 333
           + ++ V A DAD G   E  +       TGN ++       +G V  +  LD E+   Y 
Sbjct: 61  HDVILVTASDADAGSQGEDAFIFLS--VTGNFNVST-----AGVVSLATALDYESTRLYS 113

Query: 334 LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG-QYEVELAEDEPPGTPVVTLTATD 392
           L+++ TD G   +S   +              F  G  Y V    +   GT +  L  TD
Sbjct: 114 LVLSVTDSGLSTKSTQISVKVTVIAVNEFSPVFTSGGTYAVT---NTTVGTSITQLQCTD 170

Query: 393 AD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS 450
           +D   +  L Y IT G+    F+++S    G +T  + LD++  + Y +T+ A D+    
Sbjct: 171 SDLGTNAALSYSITDGDPNSVFTVSSS---GELTTVKQLDYETTQSYAITIQARDTSASQ 227

Query: 451 DTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508
             A+  V + +   N Y P F  + Y  ++ E  PIGTT               ++TYS+
Sbjct: 228 LMAVSHVDVIVQALNEYTPSFSQSEYNVTISEATPIGTT--------------GELTYSM 273

Query: 509 SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS-LSDTTDV 567
            S             F I+  +G IT  + LD E ++ Y+L VTA DG   S  S   +V
Sbjct: 274 PS----------GSPFYIDSLSGVITLKQGLDYEAVTSYVLLVTATDGDASSPKSSMVNV 323

Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615
            ++V D NDNEP F   +Y+  I E+  VGTS+  +  TD+D G NG+
Sbjct: 324 TVTVKDENDNEPTFTPAVYSVVIPENTTVGTSILSLTCTDSDSGTNGQ 371



 Score =  160 bits (389), Expect = 4e-37
 Identities = 139/457 (30%), Positives = 221/457 (48%), Gaps = 46/457 (10%)

Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQF-SEKTYTVSVDEDI 163
           L+ E   RYT+ ++A+D  +P   + S+T  + +++   N+  P F    TY +S+ ED+
Sbjct: 1   LNYETTMRYTLSIQASDGGTP--GKASTTLAV-IDVQGVNEYTPSFIPNNTYELSLAEDL 57

Query: 164 SVTDNPVIAKIKATDADVGANS--AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVR 221
           SV  + ++  + A+DAD G+    A  +  + GN    F++ S +G VSL   LDYE  R
Sbjct: 58  SVGHDVIL--VTASDADAGSQGEDAFIFLSVTGN----FNV-STAGVVSLATALDYESTR 110

Query: 222 SYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA 281
            Y LV+   D G  ++S    + + +  VN+ +P F TS    +V+ N  +G SI ++Q 
Sbjct: 111 LYSLVLSVTDSGLSTKSTQISVKVTVIAVNEFSPVF-TSGGTYAVT-NTTVGTSITQLQC 168

Query: 282 YDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341
            D+D G NA L+Y++TD    G+ +   T+   SG + T  QLD ET   Y + + A D 
Sbjct: 169 TDSDLGTNAALSYSITD----GDPNSVFTVSS-SGELTTVKQLDYETTQSYAITIQARDT 223

Query: 342 GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHY 401
                 A +               F   +Y V ++E  P GT               L Y
Sbjct: 224 SASQLMAVSHVDVIVQALNEYTPSFSQSEYNVTISEATPIGTT------------GELTY 271

Query: 402 EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSD-TAMVQINIT 460
            +  G+    F I S +G  +IT+ Q LD++    YVL V+ATD    S  ++MV + +T
Sbjct: 272 SMPSGSP---FYIDSLSG--VITLKQGLDYEAVTSYVLLVTATDGDASSPKSSMVNVTVT 326

Query: 461 --DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518
             D N+  P F  A Y+  + E+  +GT++L ++ TDSD G N Q   ++ S++ NE   
Sbjct: 327 VKDENDNEPTFTPAVYSVVIPENTTVGTSILSLTCTDSDSGTNGQFKMAIISDV-NE--- 382

Query: 519 HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555
            H  QF       A+      D   +   + TV A D
Sbjct: 383 -HTPQFTSGGSYTAVIAEDAPD-TAIGVTIATVAATD 417



 Score =  129 bits (311), Expect = 1e-27
 Identities = 121/448 (27%), Positives = 200/448 (44%), Gaps = 56/448 (12%)

Query: 11  INVLDCNDHSPVF-EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           I+V   N+++P F     YE S+ E  S G  V+ + A+D D G   E  +    VT + 
Sbjct: 31  IDVQGVNEYTPSFIPNNTYELSLAEDLSVGHDVILVTASDADAGSQGEDAFIFLSVTGN- 89

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                               F +   +G +    +LD E    Y++++  TD  S +S +
Sbjct: 90  --------------------FNVS-TAGVVSLATALDYESTRLYSLVLSVTD--SGLSTK 126

Query: 130 LSSTATIHVNIIDDNDNYPQF-SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            S+  ++ V +I  N+  P F S  TY V+     + T    I +++ TD+D+G N+A+ 
Sbjct: 127 -STQISVKVTVIAVNEFSPVFTSGGTYAVT-----NTTVGTSITQLQCTDSDLGTNAALS 180

Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
           Y+I  G+    F++ S SG+++ VK LDYE  +SY + I+A+D  +      + + + ++
Sbjct: 181 YSITDGDPNSVFTVSS-SGELTTVKQLDYETTQSYAITIQARDTSASQLMAVSHVDVIVQ 239

Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            +N+  P F  S +  ++SE  PI              G   ELTY+M     +G+   P
Sbjct: 240 ALNEYTPSFSQSEYNVTISEATPI--------------GTTGELTYSMP----SGS---P 278

Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG-GDPPRSATATXXXXXXXXXXXXXXFM 367
             ID  SG +     LD E    Y LLVTATDG    P+S+                 F 
Sbjct: 279 FYIDSLSGVITLKQGLDYEAVTSYVLLVTATDGDASSPKSSMVNVTVTVKDENDNEPTFT 338

Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT-GGNTRGRFSITSQNGRGLITVA 426
           P  Y V + E+   GT +++LT TD+D      +++    +        +  G     +A
Sbjct: 339 PAVYSVVIPENTTVGTSILSLTCTDSDSGTNGQFKMAIISDVNEHTPQFTSGGSYTAVIA 398

Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAM 454
           +          + TV+ATD+   SD A+
Sbjct: 399 EDAPDTAIGVTIATVAATDADHGSDGAI 426



 Score =  114 bits (274), Expect = 4e-23
 Identities = 100/339 (29%), Positives = 156/339 (46%), Gaps = 33/339 (9%)

Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF-KQQLYTANIMEDALVG 597
           L+ ET   Y L++ A DGG P  + TT   I V  VN+  P F     Y  ++ ED  VG
Sbjct: 1   LNYETTMRYTLSIQASDGGTPGKASTTLAVIDVQGVNEYTPSFIPNNTYELSLAEDLSVG 60

Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
             V  V A+DAD G  G   +         G+F +  A GV+    ALD ES   + L  
Sbjct: 61  HDVILVTASDADAGSQGEDAFIFLSVT---GNFNVSTA-GVVSLATALDYESTRLYSLVL 116

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
              D G   +S+ + V + +  +N+  PVF S     Y   N+ +GT+I +++  D D G
Sbjct: 117 SVTDSGLSTKSTQISVKVTVIAVNEFSPVFTSGGT--YAVTNTTVGTSITQLQCTDSDLG 174

Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPL 774
            NA + YSI  GD ++ F++     S   EL T+  LDYE+  + Y + I+A   ++  L
Sbjct: 175 TNAALSYSITDGDPNSVFTV-----SSSGELTTVKQLDYET-TQSYAITIQARDTSASQL 228

Query: 775 WNDVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVGPFGRVPAYDADVTDKLQYRILS 833
                V+++V  +N+  P     Q  +N    +  P+G            T +L Y + S
Sbjct: 229 MAVSHVDVIVQALNEYTPSFS--QSEYNVTISEATPIG-----------TTGELTYSMPS 275

Query: 834 GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
           G+      ++  +G +TL   L+        + V+ TDG
Sbjct: 276 GSP---FYIDSLSGVITLKQGLDYEAVTSYVLLVTATDG 311



 Score =  101 bits (241), Expect = 4e-19
 Identities = 71/198 (35%), Positives = 103/198 (52%), Gaps = 25/198 (12%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +I + D ND+ PVF    Y  S+ E  S+GT V+ + ATD D G NAE+ Y+I  V  D 
Sbjct: 693 RIFLSDTNDNKPVFSPTLYLTSISEATSAGTDVIPVHATDVDTGINAEITYSI--VGGDA 750

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            N                  F ++  +G + T A+LDRE +A YT+LV+A+D+  P    
Sbjct: 751 KNQ-----------------FSVNS-TGMIRTIATLDREDIASYTLLVQASDRGVPPQ-- 790

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            + T  + V I+D NDN   FS+  ++  V ED  V        I A+DAD G N+ + Y
Sbjct: 791 -TETVHVTVTILDVNDNAAVFSQSAFSARVLEDAPVGFR--FMNISASDADSGDNARLTY 847

Query: 190 AIIGGNTQMQFSIDSLSG 207
           +I  GNT    +I+S +G
Sbjct: 848 SIQSGNTDNVVAIESATG 865



 Score = 48.0 bits (109), Expect = 0.004
 Identities = 21/64 (32%), Positives = 34/64 (53%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           +H  + +LD ND++ VF    + A V E A  G   + + A+D D G NA + Y+I+   
Sbjct: 794 VHVTVTILDVNDNAAVFSQSAFSARVLEDAPVGFRFMNISASDADSGDNARLTYSIQSGN 853

Query: 67  ADTL 70
            D +
Sbjct: 854 TDNV 857


>UniRef50_UPI0000E7FFCA Cluster: PREDICTED: similar to FAT tumor
            suppressor homolog 4; n=5; Gallus gallus|Rep: PREDICTED:
            similar to FAT tumor suppressor homolog 4 - Gallus gallus
          Length = 2498

 Score =  293 bits (718), Expect = 6e-77
 Identities = 258/890 (28%), Positives = 407/890 (45%), Gaps = 75/890 (8%)

Query: 15   DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
            D ND+ PVF   +YE SV E  + G+ +LT+ ATD D G NA V+Y I      T +P  
Sbjct: 738  DVNDNPPVFSSSRYEVSVPEDKARGSELLTVSATDLDAGANALVKYRIISQQPLTSSP-- 795

Query: 75   AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134
                          VF ++  +G       LD E   ++ V ++A+D   P    L+++ 
Sbjct: 796  --------------VFLVNLTTGQFFLSQKLDYETTKQFEVELEASDGGQP---SLNTST 838

Query: 135  TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194
             + ++++D NDN P+F++ TY + V E+I    +PV      TD D    S   +     
Sbjct: 839  HVVIHVLDVNDNPPKFNQVTYDIVVFENIQ-KGSPVCT-FSVTDDDEAGFSQGHFI---- 892

Query: 195  NTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252
            +    F++D + G +SL     LD E    + L + A D      ++++   I + DVND
Sbjct: 893  HNSTFFTVD-IPGIISLRNDTELDRETTPGFTLQVWAVDAEKDGLNSSSLFHITVLDVND 951

Query: 253  NAPRFYTSLFQESVSE-NVPIGYSIV--RVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            N P F    +  +V E +  +G   V   V A D DEG NA +TY ++ +D     D+  
Sbjct: 952  NNPEFQMQSYSFAVLEGDYRLGAPAVVGHVTATDLDEGENARITYYLSSEDGDNPYDIQ- 1010

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
                + G +  +G +DRET+ KY+LL+ A+D G P R                   F   
Sbjct: 1011 ----QDGTILVNGCVDRETKEKYELLLVASDNGMPRRQNFTYISIQVLDVNDNVPQFTKV 1066

Query: 370  QYEVEL-AEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
             Y   +       G  V++++ATD D  N      +  N    F I +  G  +I ++  
Sbjct: 1067 HYAASIPVATAKEGAFVLSVSATDLDIGNNSVISYSLMNHSDIFHINNHTGE-IILLSSL 1125

Query: 429  LDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
                 +    LTV A D G     S+ ++    + +   +   FE++ Y  ++ E+ P+ 
Sbjct: 1126 AHVTADMVVTLTVIAADHGVPPLASNASVAVCLLVNDTGFGLAFESSRYEFNIPEEEPVR 1185

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
            T V  V A    + I  Q+ Y L S         H  +F I+ Q G I T   LDRE  +
Sbjct: 1186 TVVGSVKALTGSIAI--QVVYFLRS---------HTDKFAISDQ-GDIVTLATLDREDDN 1233

Query: 546  GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
             Y + V A D  VP  +    V + V D+NDN PVF + + T   + + +    +    A
Sbjct: 1234 LYNIVVEAVDSVVPPNTAIALVTVIVNDINDNPPVFSELIQTKLSLPENMAPLDLGTFSA 1293

Query: 606  TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
            TD D+G N  I Y L       G F I+ ++G + T  +LDRE +  ++LK +AID G P
Sbjct: 1294 TDLDIGDNAFISYYLQYDFA--GMFHINTSTGKLMTGMSLDREMMDNYELKIIAIDSGKP 1351

Query: 666  PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
            P S+++ + I +ED+ND+ PV      +  + EN P    I    A D D G NAV+ Y+
Sbjct: 1352 PLSASLALSIAVEDVNDNSPVLSQKLYSVTVKENDP-PHVILSTTATDKDIGYNAVIQYT 1410

Query: 726  IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEI 782
            I G     SF +    G     + T+  LDYES    Y   ++A     P L +   + +
Sbjct: 1411 IIG---ETSFHV----GELSGNISTVQPLDYES-CAHYTFTLKAFNPGEPHLQDTTNITV 1462

Query: 783  LVTDVNDNAPVMKD---FQIIF-NNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNAN 838
            +V DVN+  P+      FQI+  N+      V    R  +   D  + + Y I  GN+  
Sbjct: 1463 IVEDVNEEGPMFDKPSYFQILLDNSTAGTLVVDIDARDESKGYD--EGIFYNITDGNSEG 1520

Query: 839  LILLNETTGSMTLSPQLNTNV-PKLATMEVSVTD-GVNEIKAMMQLSVRL 886
            L  L+ T+G +TL+  LN    P   ++ V+ TD G+  +   +++SV +
Sbjct: 1521 LFNLSSTSGVLTLTRDLNKQAFPLYNSLTVTATDSGLPPLSTSVKVSVTI 1570



 Score =  277 bits (680), Expect = 2e-72
 Identities = 252/896 (28%), Positives = 405/896 (45%), Gaps = 76/896 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + + D ND+ PV     Y  S+ E   +G  VL ++A D+D G     + T  L  AD+ 
Sbjct: 327  VTIEDVNDNLPVLSQSSYNVSILENFPNGKEVLRIEAVDKDEGG---FQGTFSLTPADS- 382

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS--LDREKVARYTVLVKATDQASPVSD 128
                               F+I  + G L  R S  LDRE+     + V A D  SP  +
Sbjct: 383  ------------------PFQIS-QDGILTVRNSTLLDREQTPSIHLQVTARDHLSPYDE 423

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
              S+   I+V ++D+NDN P F++  Y   +   I++T    I ++ A D D G N AI 
Sbjct: 424  AQSA---INVLLLDENDNNPTFTDTQYEQVIF--INMTAGMSILQVAADDPDDGINGAIS 478

Query: 189  YAIIGGNTQMQFSIDSLSGDVSL--VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            + + GGN    F +D  +G +SL  V  L   + +++ L + A DGG+  RS++    ++
Sbjct: 479  FVLAGGNEDGYFELDKSTGQISLKAVIPLRVNESKNFVLWVTATDGGTNPRSSSVP--VH 536

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            I  V D+ P+F    +  SV E +     + RV+     E +N  +   +     +   D
Sbjct: 537  IFAVGDSRPQFIQKTYNVSVEEELVSPVEVARVKY----ESLNPHIPVILRVLTESATFD 592

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
            + +     +G ++T  +LD E+Q  Y L ++ +DG     +  AT              F
Sbjct: 593  VDV-----NGIIWTKIKLDFESQNNYTLNISLSDG---VTTDYATVFIQVTDVNDNSPVF 644

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
                  +++ E+   GT V ++ ATD D         T     G+  I   +  GLI + 
Sbjct: 645  GITNTTIKILENTAAGTSVTSVPATDVDTGFNGLVVYTLKGAEGKMDI---DASGLILLK 701

Query: 427  QPLDFKQERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYAPVFENAPYTASVFEDAPI 484
            + LD + +  Y L V A+D G    +A++ +   I D N+  PVF ++ Y  SV ED   
Sbjct: 702  KELDRETQGIYNLAVIASDQGQPRLSAVLNLTVVIDDVNDNPPVFSSSRYEVSVPEDKAR 761

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            G+ +L VSATD D G NA + Y +   IS + +      F++N  TG    ++ LD ET 
Sbjct: 762  GSELLTVSATDLDAGANALVKYRI---ISQQPLT-SSPVFLVNLTTGQFFLSQKLDYETT 817

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
              + + + A DGG PSL+ +T V I V+DVNDN P F Q  Y   + E+   G+ V    
Sbjct: 818  KQFEVELEASDGGQPSLNTSTHVVIHVLDVNDNPPKFNQVTYDIVVFENIQKGSPVCTFS 877

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVID-PASGVIRTNKALDRESVATHDLKAVAIDGG 663
             TD D     + H+           F +D P    +R +  LDRE+     L+  A+D  
Sbjct: 878  VTDDDEAGFSQGHF-----IHNSTFFTVDIPGIISLRNDTELDRETTPGFTLQVWAVDAE 932

Query: 664  TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS-PIG--TTIGEIRAHDPDEGPNA 720
                +S+ + HI + D+ND+ P F+    +F + E    +G    +G + A D DEG NA
Sbjct: 933  KDGLNSSSLFHITVLDVNDNNPEFQMQSYSFAVLEGDYRLGAPAVVGHVTATDLDEGENA 992

Query: 721  VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWND 777
             + Y +   D  N + ++     D   LV    +D E+ ++KYEL++ A+    P   N 
Sbjct: 993  RITYYLSSEDGDNPYDIQ----QDGTILVNGC-VDRET-KEKYELLLVASDNGMPRRQNF 1046

Query: 778  VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVTDKLQYRILSGNN 836
              + I V DVNDN P         +        G F   V A D D+ +         N+
Sbjct: 1047 TYISIQVLDVNDNVPQFTKVHYAASIPVATAKEGAFVLSVSATDLDIGNNSVISYSLMNH 1106

Query: 837  ANLILLNETTGSMTLSPQL-NTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEE 890
            +++  +N  TG + L   L +     + T+ V   D GV  + +   ++V L+  +
Sbjct: 1107 SDIFHINNHTGEIILLSSLAHVTADMVVTLTVIAADHGVPPLASNASVAVCLLVND 1162



 Score =  262 bits (643), Expect = 7e-68
 Identities = 233/808 (28%), Positives = 375/808 (46%), Gaps = 61/808 (7%)

Query: 96   SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155
            +G + T+  LD E    YT+ +  +D  +      +  AT+ + + D NDN P F     
Sbjct: 596  NGIIWTKIKLDFESQNNYTLNISLSDGVT------TDYATVFIQVTDVNDNSPVFGITNT 649

Query: 156  TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTL 215
            T+ + E+ +   +  +  + ATD D G N  + Y + G   +M   ID+ SG + L K L
Sbjct: 650  TIKILENTAAGTS--VTSVPATDVDTGFNGLVVYTLKGAEGKMD--IDA-SGLILLKKEL 704

Query: 216  DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275
            D E    Y L + A D G P  S    L + I DVNDN P F +S ++ SV E+   G  
Sbjct: 705  DRETQGIYNLAVIASDQGQPRLSAVLNLTVVIDDVNDNPPVFSSSRYEVSVPEDKARGSE 764

Query: 276  IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL 335
            ++ V A D D G NA + Y +  +    +  +   ++  +G  + S +LD ET  ++++ 
Sbjct: 765  LLTVSATDLDAGANALVKYRIISQQPLTSSPV-FLVNLTTGQFFLSQKLDYETTKQFEVE 823

Query: 336  VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395
            + A+DGG P  + +                F    Y++ + E+   G+PV T + TD DE
Sbjct: 824  LEASDGGQPSLNTSTHVVIHVLDVNDNPPKFNQVTYDIVVFENIQKGSPVCTFSVTDDDE 883

Query: 396  DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR--YVLTVSATDS--GGRSD 451
                    + G+     +  + +  G+I++    +  +E    + L V A D+   G + 
Sbjct: 884  AG-----FSQGHFIHNSTFFTVDIPGIISLRNDTELDRETTPGFTLQVWAVDAEKDGLNS 938

Query: 452  TAMVQINITDANNYAPVFENAPYTASVFE-DAPIGTTVLV--VSATDSDVGINAQITYSL 508
            +++  I + D N+  P F+   Y+ +V E D  +G   +V  V+ATD D G NA+ITY L
Sbjct: 939  SSLFHITVLDVNDNNPEFQMQSYSFAVLEGDYRLGAPAVVGHVTATDLDEGENARITYYL 998

Query: 509  SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568
            SSE  +     +D Q     Q G I  N  +DRET   Y L + A D G+P   + T + 
Sbjct: 999  SSEDGDNP---YDIQ-----QDGTILVNGCVDRETKEKYELLLVASDNGMPRRQNFTYIS 1050

Query: 569  ISVVDVNDNEPVFKQQLYTANI-MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627
            I V+DVNDN P F +  Y A+I +  A  G  V  V ATD D+G N  I Y L       
Sbjct: 1051 IQVLDVNDNVPQFTKVHYAASIPVATAKEGAFVLSVSATDLDIGNNSVISYSL---MNHS 1107

Query: 628  GSFVIDPASGVIRTNKALDRESV-ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS--P 684
              F I+  +G I    +L   +      L  +A D G PP +S   V + +  +ND+   
Sbjct: 1108 DIFHINNHTGEIILLSSLAHVTADMVVTLTVIAADHGVPPLASNASVAVCLL-VNDTGFG 1166

Query: 685  PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV-VHYSIKGGDDSNSFSLETRQGS 743
              FES    F I E  P+ T +G ++A     G  A+ V Y ++   D   F++     S
Sbjct: 1167 LAFESSRYEFNIPEEEPVRTVVGSVKAL---TGSIAIQVVYFLRSHTD--KFAI-----S 1216

Query: 744  DKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKD-FQI 799
            D+ ++VT+  LD E     Y +V+ A     PP      V ++V D+NDN PV  +  Q 
Sbjct: 1217 DQGDIVTLATLDREDD-NLYNIVVEAVDSVVPPNTAIALVTVIVNDINDNPPVFSELIQT 1275

Query: 800  IFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTLSPQLNT 857
              +  ++  P+   G   A D D+ D   + Y  L  + A +  +N +TG +     L+ 
Sbjct: 1276 KLSLPENMAPL-DLGTFSATDLDIGDNAFISY-YLQYDFAGMFHINTSTGKLMTGMSLDR 1333

Query: 858  NVPKLATME-VSVTDGVNEIKAMMQLSV 884
             +     ++ +++  G   + A + LS+
Sbjct: 1334 EMMDNYELKIIAIDSGKPPLSASLALSI 1361



 Score =  257 bits (630), Expect = 3e-66
 Identities = 258/947 (27%), Positives = 420/947 (44%), Gaps = 83/947 (8%)

Query: 13   VLDCNDHSPVF-EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71
            V D ND+ PVF E+ Q + S+ E  +    + T  ATD DIG NA + Y ++   A    
Sbjct: 1259 VNDINDNPPVFSELIQTKLSLPENMAP-LDLGTFSATDLDIGDNAFISYYLQYDFAG--- 1314

Query: 72   PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131
                             +F I+  +G L+T  SLDRE +  Y + + A D   P    LS
Sbjct: 1315 -----------------MFHINTSTGKLMTGMSLDREMMDNYELKIIAIDSGKPP---LS 1354

Query: 132  STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP-VIAKIKATDADVGANSAIRYA 190
            ++  + + + D NDN P  S+K Y+V+V E+    D P VI    ATD D+G N+ I+Y 
Sbjct: 1355 ASLALSIAVEDVNDNSPVLSQKLYSVTVKEN----DPPHVILSTTATDKDIGYNAVIQYT 1410

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            IIG   +  F +  LSG++S V+ LDYE    Y   ++A + G P   +TT + + + DV
Sbjct: 1411 IIG---ETSFHVGELSGNISTVQPLDYESCAHYTFTLKAFNPGEPHLQDTTNITVIVEDV 1467

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            N+  P F    + + + +N   G  +V + A D  +G +  + Y +TD    GN +    
Sbjct: 1468 NEEGPMFDKPSYFQILLDNSTAGTLVVDIDARDESKGYDEGIFYNITD----GNSEGLFN 1523

Query: 311  IDPRSGWVYTSGQLDRETQAKY-QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            +   SG +  +  L+++    Y  L VTATD G PP S +                F   
Sbjct: 1524 LSSTSGVLTLTRDLNKQAFPLYNSLTVTATDSGLPPLSTSVKVSVTIAPTNISLPVFSEA 1583

Query: 370  QYE-VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
             Y+   L+E   P T VV +T         + Y I  G+ +G F I      G I   + 
Sbjct: 1584 VYQPAPLSEKTLPDTFVVQITVL---YKVPVVYSIVAGDEKGYFIINPST--GTIRTGKK 1638

Query: 429  LDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
            L   ++   V +V ATDS   S  +   V + + D N++ PVF  +     + E+ P  T
Sbjct: 1639 LTV-EDSLIVFSVRATDSSTASIFNDVSVHVEVIDENDFPPVFTFSLLEQGLEENLP-AT 1696

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD-RETMS 545
             ++ + A D+D G N  +TY +   +S +       +F I+  TG + +    D  E  +
Sbjct: 1697 QIVHLIARDNDTGRNGDLTYGI---LSGDGT-----KFRIDESTGILYSTVSFDYEEEPT 1748

Query: 546  GYLLTVTARDGGVPSLS-DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
             Y + + A D G P        V + + DVND  PVF   +   ++ E+  V   V +V 
Sbjct: 1749 EYQVVIYAEDDGTPEKKRGYCTVVVKITDVNDWPPVF-NPVTPFSVNENVDVEFIVGKVT 1807

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            A D D G N  + Y L         F ID   G I+   + D E+V  + L   A++  +
Sbjct: 1808 AMDRDTGDNAFVLYSL--TGGGGNIFEIDALLGNIKIKNSPDYENVNKYTLTVTAVNNKS 1865

Query: 665  PP-QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
             P   +T  V + + D+ND+ PVF  +  +  I+  +P+G  +  + A D D+G N ++ 
Sbjct: 1866 APFYQATTNVTVLVIDVNDNAPVFAQNSYSTSINMINPVGVHVITVHATDKDQGQNGLIE 1925

Query: 724  YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEIL 783
            Y I    D N  +    +   + +++T  +L          ++ +    P  N   V  +
Sbjct: 1926 YYII--PDLNFSAFFLIEDESEGKIITTGNLS-RFEEVCLTVMAKDKGSPSLNSTAV--I 1980

Query: 784  VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD-ADVTDKL-QYRILSGNNANLIL 841
              +V DN P +  F     +       G    +  +  A+ + KL  Y I+SGN      
Sbjct: 1981 TLNVIDNRPFVPRFSENKVSISVLENTGVDHSIYTFAVAETSGKLIVYTIVSGNEKGHFR 2040

Query: 842  LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVR-L 900
            L+  +G   L   +N N  +++   + V    +   A    S  L  + + + +ITV+ +
Sbjct: 2041 LDPKSGQ--LKTAINLNYEEVSQYVILVEANEDVSSAAQVPSSGLFAQNVAMLTITVQDV 2098

Query: 901  NDMTAEQFLSPLLGFFIDGLAAIIPCPKENIY-IFSVQ-DDTDVTGN 945
            N+  A  FL+ +        +A+IP      Y + +VQ  D D  GN
Sbjct: 2099 NEKPA--FLNSM-------YSALIPSSVPYKYPVITVQATDPDAGGN 2136



 Score =  256 bits (628), Expect = 5e-66
 Identities = 231/817 (28%), Positives = 358/817 (43%), Gaps = 63/817 (7%)

Query: 9   QQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKN-AEVEYTIELVTA 67
           + + + D ND+SP F    Y  SV E ++  +TV+ ++A D+D+    + + Y++     
Sbjct: 111 RDLQLEDVNDNSPEFLQALYNTSVSEVSAINSTVIKVEAQDKDLSPLFSHISYSL----- 165

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
             L P               D F I    G ++   +LD  K+  + + V A ++     
Sbjct: 166 --LGPNS-------------DYFYIREGDGNIMVNKTLDYNKINHFNLTVLAKERFG--- 207

Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
              S+T ++ +++ D +   P FS   Y  ++ E+     + +  KI A D D G N  +
Sbjct: 208 -NNSNTVSLIIDVQDYDTLNPYFSLSVYNGTISENKLGPLSILPEKIFAKDGDTGINEKV 266

Query: 188 RYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
            Y+I           FSI + SG + +   +D E+     + I A    +  ++    +L
Sbjct: 267 YYSIKLVKPPAYSNTFSISADSGMLEVKTAVDREECPYLFVGIEAAQQDNNLKTADAVVL 326

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           + I DVNDN P    S +  S+ EN P G  ++R++A D DEG   + T+++T  D    
Sbjct: 327 VTIEDVNDNLPVLSQSSYNVSILENFPNGKEVLRIEAVDKDEG-GFQGTFSLTPADSPFQ 385

Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
           +     +  R+     S  LDRE      L VTA D   P   A +              
Sbjct: 386 ISQDGILTVRN-----STLLDREQTPSIHLQVTARDHLSPYDEAQSAINVLLLDENDNNP 440

Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGL 422
            F   QYE  +  +   G  ++ + A D D+  +  + + + GGN  G F +    G+  
Sbjct: 441 TFTDTQYEQVIFINMTAGMSILQVAADDPDDGINGAISFVLAGGNEDGYFELDKSTGQIS 500

Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
           +    PL   + + +VL V+ATD G    ++ V ++I    +  P F    Y  SV E+ 
Sbjct: 501 LKAVIPLRVNESKNFVLWVTATDGGTNPRSSSVPVHIFAVGDSRPQFIQKTYNVSVEEEL 560

Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
                V  V        +N  I   L   ++  A    D    +N   G I T   LD E
Sbjct: 561 VSPVEVARVKYE----SLNPHIPVIL-RVLTESATFDVD----VN---GIIWTKIKLDFE 608

Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
           + + Y L ++  DG     +D   V I V DVNDN PVF     T  I+E+   GTSV+ 
Sbjct: 609 SQNNYTLNISLSDG---VTTDYATVFIQVTDVNDNSPVFGITNTTIKILENTAAGTSVTS 665

Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
           V ATD D G NG + Y L      EG   ID ASG+I   K LDRE+   ++L  +A D 
Sbjct: 666 VPATDVDTGFNGLVVYTL---KGAEGKMDID-ASGLILLKKELDRETQGIYNLAVIASDQ 721

Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
           G P  S+ + + + I+D+ND+PPVF S      + E+   G+ +  + A D D G NA+V
Sbjct: 722 GQPRLSAVLNLTVVIDDVNDNPPVFSSSRYEVSVPEDKARGSELLTVSATDLDAGANALV 781

Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVR 779
            Y I       S S          +      LDYE+  K++E+ + A+    P L     
Sbjct: 782 KYRIISQQPLTS-SPVFLVNLTTGQFFLSQKLDYET-TKQFEVELEASDGGQPSLNTSTH 839

Query: 780 VEILVTDVNDNAPVMKDFQ---IIFNNYKDCFPVGPF 813
           V I V DVNDN P         ++F N +   PV  F
Sbjct: 840 VVIHVLDVNDNPPKFNQVTYDIVVFENIQKGSPVCTF 876



 Score =  218 bits (533), Expect = 2e-54
 Identities = 209/749 (27%), Positives = 347/749 (46%), Gaps = 54/749 (7%)

Query: 142 DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN-SAIRYAIIGGNTQMQF 200
           D NDN P+F +  Y  SV E  ++  N  + K++A D D+    S I Y+++G N+   F
Sbjct: 117 DVNDNSPEFLQALYNTSVSEVSAI--NSTVIKVEAQDKDLSPLFSHISYSLLGPNSDY-F 173

Query: 201 SIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260
            I    G++ + KTLDY ++  + L + A++    + SNT  L+I+++D +   P F  S
Sbjct: 174 YIREGDGNIMVNKTLDYNKINHFNLTVLAKERFG-NNSNTVSLIIDVQDYDTLNPYFSLS 232

Query: 261 LFQESVSENV--PIGYSIVRVQAYDADEGVNAELTYTM-TDKDYTGNVDLPITIDPRSGW 317
           ++  ++SEN   P+     ++ A D D G+N ++ Y++   K    +    I+ D  SG 
Sbjct: 233 VYNGTISENKLGPLSILPEKIFAKDGDTGINEKVYYSIKLVKPPAYSNTFSISAD--SGM 290

Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377
           +     +DRE      + + A    +  ++A A                    Y V + E
Sbjct: 291 LEVKTAVDREECPYLFVGIEAAQQDNNLKTADAVVLVTIEDVNDNLPVLSQSSYNVSILE 350

Query: 378 DEPPGTPVVTLTATDADEDN-RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436
           + P G  V+ + A D DE   +  + +T  ++   F I SQ+G   +  +  LD +Q   
Sbjct: 351 NFPNGKEVLRIEAVDKDEGGFQGTFSLTPADS--PFQI-SQDGILTVRNSTLLDREQTPS 407

Query: 437 YVLTVSATDSGGRSDTAMVQINI--TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494
             L V+A D     D A   IN+   D N+  P F +  Y   +F +   G ++L V+A 
Sbjct: 408 IHLQVTARDHLSPYDEAQSAINVLLLDENDNNPTFTDTQYEQVIFINMTAGMSILQVAAD 467

Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET--MSGYLLTVT 552
           D D GIN  I++ L+    NE     D  F ++  TG I+   ++         ++L VT
Sbjct: 468 DPDDGINGAISFVLAG--GNE-----DGYFELDKSTGQISLKAVIPLRVNESKNFVLWVT 520

Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612
           A DGG    S  + V + +  V D+ P F Q+ Y  ++ E+ +    V++V        L
Sbjct: 521 ATDGGTNPRS--SSVPVHIFAVGDSRPQFIQKTYNVSVEEELVSPVEVARVKYE----SL 574

Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672
           N  I   L     E  +F +D  +G+I T   LD ES   + L     DG T   ++   
Sbjct: 575 NPHIPVILRVL-TESATFDVD-VNGIIWTKIKLDFESQNNYTLNISLSDGVTTDYAT--- 629

Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732
           V I++ D+ND+ PVF     T  I EN+  GT++  + A D D G N +V Y++KG    
Sbjct: 630 VFIQVTDVNDNSPVFGITNTTIKILENTAAGTSVTSVPATDVDTGFNGLVVYTLKGA--- 686

Query: 733 NSFSLETRQGSDKAELVTM-VDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVN 788
                E +   D + L+ +  +LD E+ +  Y L + A+    P L   + + +++ DVN
Sbjct: 687 -----EGKMDIDASGLILLKKELDRET-QGIYNLAVIASDQGQPRLSAVLNLTVVIDDVN 740

Query: 789 DNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSG---NNANLILLN 843
           DN PV    +   +  +D         V A D D      ++YRI+S     ++ + L+N
Sbjct: 741 DNPPVFSSSRYEVSVPEDKARGSELLTVSATDLDAGANALVKYRIISQQPLTSSPVFLVN 800

Query: 844 ETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            TTG   LS +L+    K   +E+  +DG
Sbjct: 801 LTTGQFFLSQKLDYETTKQFEVELEASDG 829



 Score =  212 bits (518), Expect = 1e-52
 Identities = 220/771 (28%), Positives = 336/771 (43%), Gaps = 75/771 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND+SPV   + Y  +V+E       +L+  ATD+DIG NA ++YTI   T+   
Sbjct: 1361 IAVEDVNDNSPVLSQKLYSVTVKEN-DPPHVILSTTATDKDIGYNAVIQYTIIGETS--- 1416

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F +   SG + T   LD E  A YT  +KA +   P    L
Sbjct: 1417 -------------------FHVGELSGNISTVQPLDYESCAHYTFTLKAFNPGEP---HL 1454

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTY-TVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
              T  I V + D N+  P F + +Y  + +D     T   ++  I A D   G +  I Y
Sbjct: 1455 QDTTNITVIVEDVNEEGPMFDKPSYFQILLDNS---TAGTLVVDIDARDESKGYDEGIFY 1511

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR-LVIRAQDGGSPSRSNTTQLLINIR 248
             I  GN++  F++ S SG ++L + L+ +    Y  L + A D G P  S + ++ + I 
Sbjct: 1512 NITDGNSEGLFNLSSTSGVLTLTRDLNKQAFPLYNSLTVTATDSGLPPLSTSVKVSVTIA 1571

Query: 249  DVNDNAPRFYTSLFQES-VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
              N + P F  +++Q + +SE       +V++            + Y++   D  G    
Sbjct: 1572 PTNISLPVFSEAVYQPAPLSEKTLPDTFVVQITVL-----YKVPVVYSIVAGDEKGY--- 1623

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
               I+P +G + T  +L  E  +     V ATD          +              F 
Sbjct: 1624 -FIINPSTGTIRTGKKLTVE-DSLIVFSVRATDSSTASIFNDVSVHVEVIDENDFPPVFT 1681

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITV 425
                E  L E+  P T +V L A D D   +  L Y I  G+   +F I    G    TV
Sbjct: 1682 FSLLEQGL-EENLPATQIVHLIARDNDTGRNGDLTYGILSGDGT-KFRIDESTGILYSTV 1739

Query: 426  AQPLDFKQE-RRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
            +   D+++E   Y + + A D G    +     V + ITD N++ PVF N     SV E+
Sbjct: 1740 S--FDYEEEPTEYQVVIYAEDDGTPEKKRGYCTVVVKITDVNDWPPVF-NPVTPFSVNEN 1796

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
              +   V  V+A D D G NA + YSL+    N         F I+   G I      D 
Sbjct: 1797 VDVEFIVGKVTAMDRDTGDNAFVLYSLTGGGGN--------IFEIDALLGNIKIKNSPDY 1848

Query: 542  ETMSGYLLTVTA-RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
            E ++ Y LTVTA  +   P    TT+V + V+DVNDN PVF Q  Y+ +I     VG  V
Sbjct: 1849 ENVNKYTLTVTAVNNKSAPFYQATTNVTVLVIDVNDNAPVFAQNSYSTSINMINPVGVHV 1908

Query: 601  SQVGATDADVGLNGRIHYELDPKDREEGSFVI-DPASGVIRTNKALDR-ESVATHDLKAV 658
              V ATD D G NG I Y + P       F+I D + G I T   L R E V    L  +
Sbjct: 1909 ITVHATDKDQGQNGLIEYYIIPDLNFSAFFLIEDESEGKIITTGNLSRFEEVC---LTVM 1965

Query: 659  AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
            A D G+P  +ST ++ + + D     P F  + ++  + EN+ +  +I         E  
Sbjct: 1966 AKDKGSPSLNSTAVITLNVIDNRPFVPRFSENKVSISVLENTGVDHSIYTFAV---AETS 2022

Query: 719  NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
              ++ Y+I  G++   F L+ + G    +L T ++L+YE    +Y +++ A
Sbjct: 2023 GKLIVYTIVSGNEKGHFRLDPKSG----QLKTAINLNYEEV-SQYVILVEA 2068



 Score =  186 bits (452), Expect = 1e-44
 Identities = 154/539 (28%), Positives = 244/539 (45%), Gaps = 59/539 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V+D ND  PVF     E  + E   + T ++ L A D D G+N ++ Y I  ++ D  
Sbjct: 1668 VEVIDENDFPPVFTFSLLEQGLEENLPA-TQIVHLIARDNDTGRNGDLTYGI--LSGDGT 1724

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLD-REKVARYTVLVKATDQASPVSDR 129
                               FRID  +G L +  S D  E+   Y V++ A D  +P   R
Sbjct: 1725 K------------------FRIDESTGILYSTVSFDYEEEPTEYQVVIYAEDDGTPEKKR 1766

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
                 T+ V I D ND  P F+  T   SV+E++ V    ++ K+ A D D G N+ + Y
Sbjct: 1767 --GYCTVVVKITDVNDWPPVFNPVT-PFSVNENVDVEF--IVGKVTAMDRDTGDNAFVLY 1821

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS-PSRSNTTQLLINIR 248
            ++ GG   + F ID+L G++ +  + DYE V  Y L + A +  S P    TT + + + 
Sbjct: 1822 SLTGGGGNI-FEIDALLGNIKIKNSPDYENVNKYTLTVTAVNNKSAPFYQATTNVTVLVI 1880

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY-TMTDKDYTGNVDL 307
            DVNDNAP F  + +  S++   P+G  ++ V A D D+G N  + Y  + D +++     
Sbjct: 1881 DVNDNAPVFAQNSYSTSINMINPVGVHVITVHATDKDQGQNGLIEYYIIPDLNFSAFF-- 1938

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
             +  D   G + T+G L R  +    L V A D G P  ++TA               F 
Sbjct: 1939 -LIEDESEGKIITTGNLSRFEEVC--LTVMAKDKGSPSLNSTAVITLNVIDNRPFVPRFS 1995

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
              +  + + E+      + T    +      + Y I  GN +G F +  ++G+  +  A 
Sbjct: 1996 ENKVSISVLENTGVDHSIYTFAVAETS-GKLIVYTIVSGNEKGHFRLDPKSGQ--LKTAI 2052

Query: 428  PLDFKQERRYVLTVSATD---------SGG--RSDTAMVQINITDANNYAPVFENAPYTA 476
             L++++  +YV+ V A +         S G    + AM+ I + D N   P F N+ Y+A
Sbjct: 2053 NLNYEEVSQYVILVEANEDVSSAAQVPSSGLFAQNVAMLTITVQDVNE-KPAFLNSMYSA 2111

Query: 477  SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
             +    P    V+ V ATD D G N  +TYSL          +H +QF +N  TG I T
Sbjct: 2112 LIPSSVPYKYPVITVQATDPDAGGNGLLTYSL---------LNHQEQFDVNENTGQIYT 2161



 Score =  184 bits (449), Expect = 2e-44
 Identities = 190/732 (25%), Positives = 317/732 (43%), Gaps = 70/732 (9%)

Query: 13   VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72
            V D N+  P+F+   Y   + + +++GT V+ + A D+  G +  + Y I    ++ L  
Sbjct: 1464 VEDVNEEGPMFDKPSYFQILLDNSTAGTLVVDIDARDESKGYDEGIFYNITDGNSEGL-- 1521

Query: 73   EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVL-VKATDQASPVSDRLS 131
                             F +   SG L     L+++    Y  L V ATD   P    LS
Sbjct: 1522 -----------------FNLSSTSGVLTLTRDLNKQAFPLYNSLTVTATDSGLPP---LS 1561

Query: 132  STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191
            ++  + V I   N + P FSE  Y  +   + ++ D  V+         V     + Y+I
Sbjct: 1562 TSVKVSVTIAPTNISLPVFSEAVYQPAPLSEKTLPDTFVV------QITVLYKVPVVYSI 1615

Query: 192  IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251
            + G+ +  F I+  +G +   K L  E        +RA D  + S  N   + + + D N
Sbjct: 1616 VAGDEKGYFIINPSTGTIRTGKKLTVEDSLIV-FSVRATDSSTASIFNDVSVHVEVIDEN 1674

Query: 252  DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311
            D  P F  SL ++ + EN+P    IV + A D D G N +LTY +   D T        I
Sbjct: 1675 DFPPVFTFSLLEQGLEENLP-ATQIVHLIARDNDTGRNGDLTYGILSGDGT-----KFRI 1728

Query: 312  DPRSGWVYTSGQLDRETQ-AKYQLLVTATDGGDPPRS-ATATXXXXXXXXXXXXXXFMPG 369
            D  +G +Y++   D E +  +YQ+++ A D G P +     T              F P 
Sbjct: 1729 DESTGILYSTVSFDYEEEPTEYQVVIYAEDDGTPEKKRGYCTVVVKITDVNDWPPVFNPV 1788

Query: 370  QYEVELAEDEPPGTPVVTLTATDADE-DNR-LHYEITGGNTRGRFSITSQNGRGLITVAQ 427
                 + E+      V  +TA D D  DN  + Y +TGG     F I +  G   I +  
Sbjct: 1789 T-PFSVNENVDVEFIVGKVTAMDRDTGDNAFVLYSLTGGGGN-IFEIDALLGN--IKIKN 1844

Query: 428  PLDFKQERRYVLTVSATDSGGR---SDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
              D++   +Y LTV+A ++        T  V + + D N+ APVF    Y+ S+    P+
Sbjct: 1845 SPDYENVNKYTLTVTAVNNKSAPFYQATTNVTVLVIDVNDNAPVFAQNSYSTSINMINPV 1904

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT-GAITTNKLLDRET 543
            G  V+ V ATD D G N  I Y +  +++  A       F+I  ++ G I T   L R  
Sbjct: 1905 GVHVITVHATDKDQGQNGLIEYYIIPDLNFSAF------FLIEDESEGKIITTGNLSR-- 1956

Query: 544  MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
                 LTV A+D G PSL+ T  + ++V+D     P F +   + +++E+  V  S+   
Sbjct: 1957 FEEVCLTVMAKDKGSPSLNSTAVITLNVIDNRPFVPRFSENKVSISVLENTGVDHSIYTF 2016

Query: 604  GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID-- 661
               +     +G++         E+G F +DP SG ++T   L+ E V+ + +   A +  
Sbjct: 2017 AVAET----SGKLIVYTIVSGNEKGHFRLDPKSGQLKTAINLNYEEVSQYVILVEANEDV 2072

Query: 662  --GGTPPQS-----STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
                  P S     +  ++ I ++D+N+ P  F +   +  I  + P    +  ++A DP
Sbjct: 2073 SSAAQVPSSGLFAQNVAMLTITVQDVNEKP-AFLNSMYSALIPSSVPYKYPVITVQATDP 2131

Query: 715  DEGPNAVVHYSI 726
            D G N ++ YS+
Sbjct: 2132 DAGGNGLLTYSL 2143



 Score =  151 bits (365), Expect = 4e-34
 Identities = 173/657 (26%), Positives = 282/657 (42%), Gaps = 52/657 (7%)

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYTG 303
           + + DVNDN+P F  +L+  SVSE   I  ++++V+A D D   + + ++Y++       
Sbjct: 113 LQLEDVNDNSPEFLQALYNTSVSEVSAINSTVIKVEAQDKDLSPLFSHISYSLLGP---- 168

Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
           N D    I    G +  +  LD      + L V A +      S T +            
Sbjct: 169 NSDY-FYIREGDGNIMVNKTLDYNKINHFNLTVLAKERFGN-NSNTVSLIIDVQDYDTLN 226

Query: 364 XXFMPGQYEVELAEDE--PPGTPVVTLTATDADE--DNRLHYEITGGNT---RGRFSITS 416
             F    Y   ++E++  P       + A D D   + +++Y I           FSI++
Sbjct: 227 PYFSLSVYNGTISENKLGPLSILPEKIFAKDGDTGINEKVYYSIKLVKPPAYSNTFSISA 286

Query: 417 QNGRGLITVAQPLDFKQERRYV---LTVSATDSGGRSDTAMVQINITDANNYAPVFENAP 473
            +G  ++ V   +D ++E  Y+   +  +  D+  ++  A+V + I D N+  PV   + 
Sbjct: 287 DSG--MLEVKTAVD-REECPYLFVGIEAAQQDNNLKTADAVVLVTIEDVNDNLPVLSQSS 343

Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
           Y  S+ E+ P G  VL + A D D G   Q T+SL+           D  F I+ Q G +
Sbjct: 344 YNVSILENFPNGKEVLRIEAVDKDEG-GFQGTFSLTPA---------DSPFQIS-QDGIL 392

Query: 534 TTNK--LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
           T     LLDRE      L VTARD   P     + + + ++D NDN P F    Y   I 
Sbjct: 393 TVRNSTLLDREQTPSIHLQVTARDHLSPYDEAQSAINVLLLDENDNNPTFTDTQYEQVIF 452

Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA 651
            +   G S+ QV A D D G+NG I + L     E+G F +D ++G I     +      
Sbjct: 453 INMTAGMSILQVAADDPDDGINGAISFVL-AGGNEDGYFELDKSTGQISLKAVIPLRVNE 511

Query: 652 THD--LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
           + +  L   A DGGT P+SS+V VHI    + DS P F     T+ +S    + + +   
Sbjct: 512 SKNFVLWVTATDGGTNPRSSSVPVHIFA--VGDSRPQFIQK--TYNVSVEEELVSPVEVA 567

Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
           R       P+  V   +    +S +F ++         + T + LD+ES +  Y L I  
Sbjct: 568 RVKYESLNPHIPVILRVL--TESATFDVDV-----NGIIWTKIKLDFES-QNNYTLNISL 619

Query: 770 ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV-TDKLQ 828
           +     +   V I VTDVNDN+PV           ++         VPA D D   + L 
Sbjct: 620 SDGVTTDYATVFIQVTDVNDNSPVFGITNTTIKILENTAAGTSVTSVPATDVDTGFNGLV 679

Query: 829 YRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSV 884
              L G    + +  + +G + L  +L+     +  + V  +D G   + A++ L+V
Sbjct: 680 VYTLKGAEGKMDI--DASGLILLKKELDRETQGIYNLAVIASDQGQPRLSAVLNLTV 734



 Score = 81.4 bits (192), Expect = 3e-13
 Identities = 83/264 (31%), Positives = 120/264 (45%), Gaps = 17/264 (6%)

Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG-LNGRIHYELDPKDRE 626
           ++ + DVNDN P F Q LY  ++ E + + ++V +V A D D+  L   I Y L   + +
Sbjct: 112 DLQLEDVNDNSPEFLQALYNTSVSEVSAINSTVIKVEAQDKDLSPLFSHISYSLLGPNSD 171

Query: 627 EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686
              F I    G I  NK LD   +   +L  +A +      S+TV + I ++D +   P 
Sbjct: 172 --YFYIREGDGNIMVNKTLDYNKINHFNLTVLAKE-RFGNNSNTVSLIIDVQDYDTLNPY 228

Query: 687 FESDCLTFYISEN--SPIGTTIGEIRAHDPDEGPNAVVHYSI---KGGDDSNSFSLETRQ 741
           F        ISEN   P+     +I A D D G N  V+YSI   K    SN+FS+    
Sbjct: 229 FSLSVYNGTISENKLGPLSILPEKIFAKDGDTGINEKVYYSIKLVKPPAYSNTFSISADS 288

Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN-DVRVEILVTDVNDNAPVMKDFQII 800
           G    E+ T VD + E P     +        L   D  V + + DVNDN PV+   Q  
Sbjct: 289 G--MLEVKTAVDRE-ECPYLFVGIEAAQQDNNLKTADAVVLVTIEDVNDNLPVLS--QSS 343

Query: 801 FN-NYKDCFPVG-PFGRVPAYDAD 822
           +N +  + FP G    R+ A D D
Sbjct: 344 YNVSILENFPNGKEVLRIEAVDKD 367



 Score = 37.9 bits (84), Expect = 4.0
 Identities = 18/44 (40%), Positives = 22/44 (50%)

Query: 8   HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD 51
           H  I+VLD ND+ P F    Y+  V E    G+ V T   TD D
Sbjct: 839 HVVIHVLDVNDNPPKFNQVTYDIVVFENIQKGSPVCTFSVTDDD 882


>UniRef50_A7RQ21 Cluster: Predicted protein; n=2; Nematostella
            vectensis|Rep: Predicted protein - Nematostella vectensis
          Length = 1888

 Score =  288 bits (706), Expect = 2e-75
 Identities = 230/812 (28%), Positives = 380/812 (46%), Gaps = 65/812 (8%)

Query: 90   FRIDGRSGALLTRASLDRE--KVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
            FR+D  SG +  R+ LD E  K  R+T   + T   +  ++ + S A + + + D NDN 
Sbjct: 776  FRVDPYSGDVRVRSGLDYETVKTHRFTAEARNTRDNTDYAN-IDSEADVKIVLRDLNDNP 834

Query: 148  PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
            P+F E +Y  ++ E   V     +  + A D D G N    Y +    +Q  FS+D  +G
Sbjct: 835  PEFFELSYRDTLPESAPV--GTTVLSVTARDLDSGVNGQFHYFV---ESQF-FSVDPYTG 888

Query: 208  DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
             ++  + LD+E   ++  ++ AQD G+P+R+ T ++++ + +VNDNAPRF  SL+   V+
Sbjct: 889  WITTKRPLDFETNPTHSFLVVAQDSGNPARNGTARVIVELTNVNDNAPRFSQSLYNVFVA 948

Query: 268  ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV-YTSGQLDR 326
            E+      +  VQA D D   N  +TY++   D T N      I+ ++G +   S +   
Sbjct: 949  EDAGSDQLVATVQATDKD---NDPVTYSIASGDNTTN----FVINNKTGVIKLVSNRKPE 1001

Query: 327  ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386
                 Y + ++A+DG    ++                       Y   + ED+PP T V+
Sbjct: 1002 LIGPYYTMNISASDGLHVSQAMVIVAIQDVNNHKPVFTDC--ASYHPVVMEDDPPNTFVM 1059

Query: 387  TLTATDAD--EDNRLHYEI-TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443
             + A D D   +  + Y I         F+I  +   G++T  Q  D +++  Y + +  
Sbjct: 1060 QVHADDQDTGANGEVIYSIEKPPGALSYFAIDDKT--GIVTTLQSFDREEKPVYQIRIIG 1117

Query: 444  TDSG-GRSDTA-------MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495
             D G G S  A        V I I D N++ PVF+N  Y A++ ED  +G +VL VSATD
Sbjct: 1118 RDGGLGSSRGAERLMGVCQVDIRIGDKNDHDPVFQNKQYEATIKEDFEVGRSVLHVSATD 1177

Query: 496  SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG------YLL 549
            +D G NA++TYS+  +         +  F I+  TG +T+   L  E  S          
Sbjct: 1178 ADAGSNAKLTYSIQPQ---------NDYFAIDRATGTVTSKMSLLSEAKSEGQSSRVISF 1228

Query: 550  TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
             V A D G  S    T V I+V+D+ ++ PVF Q +Y   + ED  +G+S+ Q+ A+   
Sbjct: 1229 NVVANDNGNVSRKTVTLVRITVLDLGNDPPVFSQGVYVVTVREDIAIGSSLIQLSAS--- 1285

Query: 610  VGLNGRIHYEL----DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
               N  I+Y +     P       F I  + G++  +  LD +  +   L  +  +   P
Sbjct: 1286 TKTNKLIYYSIVPGNVPSSNNPPRFQIRISKGIVWNSHRLDHKETSNFSL-TIRAETTDP 1344

Query: 666  PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
            P S+   + I +ED+ND+PP F       ++SEN+PIG+++ ++ A D D G N  V YS
Sbjct: 1345 PMSAFANLKIFLEDVNDNPPEFVMPRYQGHVSENAPIGSSVLQVSARDRDSGENGRVTYS 1404

Query: 726  IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEI 782
                 DS+ F L+   G     + T  + D E+ + +Y L ++A    SP    D  VEI
Sbjct: 1405 FVQDKDSDKFGLDENTGL----VTTREEFDREA-QGRYTLALKARDNGSPQKTTDTIVEI 1459

Query: 783  LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLI 840
            ++TD NDN P+ ++     +  +         +V A D D  V  ++ Y I  GN     
Sbjct: 1460 IITDENDNPPIFEEKVYNISVLESAASGMELLKVSAVDRDFGVNARVSYYISEGNINGAF 1519

Query: 841  LLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
             +N   G++ L+  L+        + ++  DG
Sbjct: 1520 EVNREFGTIRLAGTLDRENVDHYKLTLTAKDG 1551



 Score =  287 bits (703), Expect = 4e-75
 Identities = 234/798 (29%), Positives = 372/798 (46%), Gaps = 65/798 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I + D ND+ P F    Y  ++ E A  GTTVL++ A D D G N +  Y +E      
Sbjct: 824  KIVLRDLNDNPPEFFELSYRDTLPESAPVGTTVLSVTARDLDSGVNGQFHYFVE------ 877

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                                F +D  +G + T+  LD E    ++ LV A D  +P  + 
Sbjct: 878  -----------------SQFFSVDPYTGWITTKRPLDFETNPTHSFLVVAQDSGNPARN- 919

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
               TA + V + + NDN P+FS+  Y V V ED     + ++A ++ATD D   N  + Y
Sbjct: 920  --GTARVIVELTNVNDNAPRFSQSLYNVFVAEDAG--SDQLVATVQATDKD---NDPVTY 972

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLV-IRAQDGGSPSRSNTTQLLINIR 248
            +I  G+    F I++ +G + LV     E +  Y  + I A DG   S++    +++ I+
Sbjct: 973  SIASGDNTTNFVINNKTGVIKLVSNRKPELIGPYYTMNISASDGLHVSQA---MVIVAIQ 1029

Query: 249  DVNDNAPRFYT-SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            DVN++ P F   + +   V E+ P    +++V A D D G N E+ Y++      G +  
Sbjct: 1030 DVNNHKPVFTDCASYHPVVMEDDPPNTFVMQVHADDQDTGANGEVIYSIEKPP--GALSY 1087

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPPRSA-----TATXXXXXXXXXX 361
               ID ++G V T    DRE +  YQ+ +   DGG    R A                  
Sbjct: 1088 -FAIDDKTGIVTTLQSFDREEKPVYQIRIIGRDGGLGSSRGAERLMGVCQVDIRIGDKND 1146

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTR---GRFSITS 416
                F   QYE  + ED   G  V+ ++ATDAD  +  +L Y I   N      R + T 
Sbjct: 1147 HDPVFQNKQYEATIKEDFEVGRSVLHVSATDADAGSNAKLTYSIQPQNDYFAIDRATGTV 1206

Query: 417  QNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPY 474
             +   L++ A+  + +  R     V A D+G   R    +V+I + D  N  PVF    Y
Sbjct: 1207 TSKMSLLSEAKS-EGQSSRVISFNVVANDNGNVSRKTVTLVRITVLDLGNDPPVFSQGVY 1265

Query: 475  TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
              +V ED  IG++++ +SA+      N  I YS+     N   +++  +F I    G + 
Sbjct: 1266 VVTVREDIAIGSSLIQLSASTKT---NKLIYYSIVP--GNVPSSNNPPRFQIRISKGIVW 1320

Query: 535  TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
             +  LD +  S + LT+ A     P +S   +++I + DVNDN P F    Y  ++ E+A
Sbjct: 1321 NSHRLDHKETSNFSLTIRAETTD-PPMSAFANLKIFLEDVNDNPPEFVMPRYQGHVSENA 1379

Query: 595  LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654
             +G+SV QV A D D G NGR+ Y    +D++   F +D  +G++ T +  DRE+   + 
Sbjct: 1380 PIGSSVLQVSARDRDSGENGRVTYSF-VQDKDSDKFGLDENTGLVTTREEFDREAQGRYT 1438

Query: 655  LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
            L   A D G+P +++  IV I I D ND+PP+FE       + E++  G  + ++ A D 
Sbjct: 1439 LALKARDNGSPQKTTDTIVEIIITDENDNPPIFEEKVYNISVLESAASGMELLKVSAVDR 1498

Query: 715  DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL 774
            D G NA V Y I  G+ + +F +    G+    +     LD E+    Y+L + A     
Sbjct: 1499 DFGVNARVSYYISEGNINGAFEVNREFGT----IRLAGTLDRENV-DHYKLTLTAKDGKY 1553

Query: 775  WNDVRVEILVTDVNDNAP 792
              +  V + V D+NDN P
Sbjct: 1554 SGEATVNVYVLDINDNNP 1571



 Score =  280 bits (686), Expect = 5e-73
 Identities = 216/733 (29%), Positives = 347/733 (47%), Gaps = 59/733 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + + + ND++P F    Y   V E A S   V T++ATD+D   N  V Y+I     +T 
Sbjct: 926  VELTNVNDNAPRFSQSLYNVFVAEDAGSDQLVATVQATDKD---NDPVTYSIASGD-NTT 981

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARY-TVLVKATDQASPVSDR 129
            N                  F I+ ++G +   ++   E +  Y T+ + A+D        
Sbjct: 982  N------------------FVINNKTGVIKLVSNRKPELIGPYYTMNISASDGLHV---- 1019

Query: 130  LSSTATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
              S A + V I D N++ P F++  +Y   V ED     N  + ++ A D D GAN  + 
Sbjct: 1020 --SQAMVIVAIQDVNNHKPVFTDCASYHPVVMEDDP--PNTFVMQVHADDQDTGANGEVI 1075

Query: 189  YAIIGGNTQMQ-FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL--- 244
            Y+I      +  F+ID  +G V+ +++ D E+   Y++ I  +DGG  S     +L+   
Sbjct: 1076 YSIEKPPGALSYFAIDDKTGIVTTLQSFDREEKPVYQIRIIGRDGGLGSSRGAERLMGVC 1135

Query: 245  ---INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
               I I D ND+ P F    ++ ++ E+  +G S++ V A DAD G NA+LTY++  ++ 
Sbjct: 1136 QVDIRIGDKNDHDPVFQNKQYEATIKEDFEVGRSVLHVSATDADAGSNAKLTYSIQPQND 1195

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
               +D           + +  + + ++       V A D G+  R               
Sbjct: 1196 YFAIDRATGTVTSKMSLLSEAKSEGQSSRVISFNVVANDNGNVSRKTVTLVRITVLDLGN 1255

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG-----RFSITS 416
                F  G Y V + ED   G+ ++ L+A+    +  ++Y I  GN        RF I  
Sbjct: 1256 DPPVFSQGVYVVTVREDIAIGSSLIQLSAS-TKTNKLIYYSIVPGNVPSSNNPPRFQI-- 1312

Query: 417  QNGRGLITVAQPLDFKQERRYVLTVSA-TDSGGRSDTAMVQINITDANNYAPVFENAPYT 475
            +  +G++  +  LD K+   + LT+ A T     S  A ++I + D N+  P F    Y 
Sbjct: 1313 RISKGIVWNSHRLDHKETSNFSLTIRAETTDPPMSAFANLKIFLEDVNDNPPEFVMPRYQ 1372

Query: 476  ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
              V E+APIG++VL VSA D D G N ++TYS   +  ++       +F ++  TG +TT
Sbjct: 1373 GHVSENAPIGSSVLQVSARDRDSGENGRVTYSFVQDKDSD-------KFGLDENTGLVTT 1425

Query: 536  NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
             +  DRE    Y L + ARD G P  +  T VEI + D NDN P+F++++Y  +++E A 
Sbjct: 1426 REEFDREAQGRYTLALKARDNGSPQKTTDTIVEIIITDENDNPPIFEEKVYNISVLESAA 1485

Query: 596  VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655
             G  + +V A D D G+N R+ Y +  +    G+F ++   G IR    LDRE+V  + L
Sbjct: 1486 SGMELLKVSAVDRDFGVNARVSYYIS-EGNINGAFEVNREFGTIRLAGTLDRENVDHYKL 1544

Query: 656  KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
               A DG     S    V++ + DIND+ P FE       +SEN P GT + ++RA DPD
Sbjct: 1545 TLTAKDG---KYSGEATVNVYVLDINDNNPKFEKSHYRVNVSENRPAGTLVVKLRASDPD 1601

Query: 716  EGPNAVVHYSIKG 728
             G +    Y I G
Sbjct: 1602 LGESGKFLYDISG 1614



 Score =  274 bits (673), Expect = 2e-71
 Identities = 260/892 (29%), Positives = 411/892 (46%), Gaps = 90/892 (10%)

Query: 11   INVLDCNDHSPVFEM--QQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68
            I V D ND++P F +  +    S+ +   +GTTV  + A DQD G +A V+Y +E   AD
Sbjct: 211  ITVTDINDNAPRFAIPREPLVTSIHQFRPAGTTVTKVTAYDQDSGSHALVKYGLE--NAD 268

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
            +                    F I  ++G + T A L   +   Y  +V ATD   P   
Sbjct: 269  SFP------------------FTITPQTGVIKTTAELRHFERDFYAFVVTATDSTPPFHK 310

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
                  T ++ + D NDN P F++  Y V V E++      VI +  A D D GAN+ + 
Sbjct: 311  -----VTANIQLGDVNDNPPLFAQPVYKVFVRENLQ--GGHVIGQFAARDPDKGANARVT 363

Query: 189  YAIIG---GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
            Y+II      +   FSI   +G ++ + TLD E +  + L I+A+D G P  S   Q++I
Sbjct: 364  YSIINFEDSRSDNLFSIHPFTGVLTALSTLDREDLSRHILTIQAKDTGVPRMSGLAQIVI 423

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
             + DVND+APRF +  F   +  N P    + + +A D D G N  + Y++      GN 
Sbjct: 424  IVDDVNDHAPRFSSGSFHVEIPLNTPPDSRVFQARALDPDGGHNGLVRYSIIQ----GNK 479

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
                +I+   G ++   +L   T     + VT  D G P RS+TA               
Sbjct: 480  QGYFSINHIDGSLFLDEKL--TTLEPIDIKVT-RDMGQPERSSTA-DIRIFIHVQAGPPQ 535

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV 425
            F+   +   + E+EP G  VV ++A   D    + Y I  GN  G F +    G G +T 
Sbjct: 536  FLSSPFVGNVTENEPKGAFVVHISAASLDP---VMYSIVSGNEAGNFRL--HPGVGWLTT 590

Query: 426  AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVF---ENAPYTASVFEDA 482
             +PLD +++ RY + V A D   R     V +N+ + N+  P F    N     +V +D 
Sbjct: 591  VRPLDNEKQSRYKIIVMAMDLKNRVSKVEVIVNVLNVNDNKPKFVNIRNGIIEGNVLKDV 650

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
             +G+ V+V+ A D+D    + I   LS  I +E    +   F +N + G +T+ ++L R+
Sbjct: 651  AVGSRVMVIDAVDAD---RSDI---LSYRIEDEKARRY---FSVNNE-GVVTSTRVL-RD 699

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
              S YL  V+  D G P +       + ++     +P   QQ    +I E A +GT V  
Sbjct: 700  LDSPYLFKVSVSDNGKPPMVAQAMARVVLLKY---QPQQDQQ--RTSIQESAALGTRVFT 754

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
            +    A    N R +  + P    E  F +DP SG +R    LD E+V TH   A A + 
Sbjct: 755  L--LTAKPIRNAR-YSIVSPL---ETKFRVDPYSGDVRVRSGLDYETVKTHRFTAEARNT 808

Query: 663  GTPPQ----SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
                      S   V I + D+ND+PP F        + E++P+GTT+  + A D D G 
Sbjct: 809  RDNTDYANIDSEADVKIVLRDLNDNPPEFFELSYRDTLPESAPVGTTVLSVTARDLDSGV 868

Query: 719  NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPRKKYELVIRAASPPLWN- 776
            N   HY +    +S  FS++   G     + T   LD+E +P   + +V + +  P  N 
Sbjct: 869  NGQFHYFV----ESQFFSVDPYTG----WITTKRPLDFETNPTHSFLVVAQDSGNPARNG 920

Query: 777  DVRVEILVTDVNDNAPVMKDFQIIFNNY--KDCFPVGPFGRVPAYDADVTDKLQYRILSG 834
              RV + +T+VNDNAP  +  Q ++N +  +D         V A D D  D + Y I SG
Sbjct: 921  TARVIVELTNVNDNAP--RFSQSLYNVFVAEDAGSDQLVATVQATDKD-NDPVTYSIASG 977

Query: 835  NNANLILLNETTGSMTL-SPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVR 885
            +N    ++N  TG + L S +    +    TM +S +DG++  +AM+ ++++
Sbjct: 978  DNTTNFVINNKTGVIKLVSNRKPELIGPYYTMNISASDGLHVSQAMVIVAIQ 1029



 Score =  240 bits (587), Expect = 5e-61
 Identities = 213/777 (27%), Positives = 347/777 (44%), Gaps = 85/777 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I + D NDH PVF+ +QYEA+++E    G +VL + ATD D G NA++ Y+I+       
Sbjct: 1139 IRIGDKNDHDPVFQNKQYEATIKEDFEVGRSVLHVSATDADAGSNAKLTYSIQ------- 1191

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASL--DREKVARYTVLVKATDQASPVSD 128
             P++             D F ID  +G + ++ SL  + +   + + ++     A+   +
Sbjct: 1192 -PQN-------------DYFAIDRATGTVTSKMSLLSEAKSEGQSSRVISFNVVANDNGN 1237

Query: 129  RLSSTAT-IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
                T T + + ++D  ++ P FS+  Y V+V EDI++  + +        A    N  I
Sbjct: 1238 VSRKTVTLVRITVLDLGNDPPVFSQGVYVVTVREDIAIGSSLI-----QLSASTKTNKLI 1292

Query: 188  RYAIIGGNTQM-----QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
             Y+I+ GN        +F I    G V     LD+++  ++ L IRA+    P  S    
Sbjct: 1293 YYSIVPGNVPSSNNPPRFQIRISKGIVWNSHRLDHKETSNFSLTIRAETT-DPPMSAFAN 1351

Query: 243  LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT-DKDY 301
            L I + DVNDN P F    +Q  VSEN PIG S+++V A D D G N  +TY+   DKD 
Sbjct: 1352 LKIFLEDVNDNPPEFVMPRYQGHVSENAPIGSSVLQVSARDRDSGENGRVTYSFVQDKDS 1411

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
                     +D  +G V T  + DRE Q +Y L + A D G P ++              
Sbjct: 1412 D-----KFGLDENTGLVTTREEFDREAQGRYTLALKARDNGSPQKTTDTIVEIIITDEND 1466

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419
                F    Y + + E    G  ++ ++A D D   + R+ Y I+ GN  G F +  + G
Sbjct: 1467 NPPIFEEKVYNISVLESAASGMELLKVSAVDRDFGVNARVSYYISEGNINGAFEVNREFG 1526

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479
               I +A  LD +    Y LT++A D G  S  A V + + D N+  P FE + Y  +V 
Sbjct: 1527 T--IRLAGTLDRENVDHYKLTLTAKD-GKYSGEATVNVYVLDINDNNPKFEKSHYRVNVS 1583

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSE--ISNEAVAHHDQQFVINPQTGAITTNK 537
            E+ P GT V+ + A+D D+G + +  Y +S +  +    V  +  +F   P  G +  N 
Sbjct: 1584 ENRPAGTLVVKLRASDPDLGESGKFLYDISGQGLMIVGDVNDNKPRFPDEPYIGHVMENL 1643

Query: 538  LLDRETMSGYLLTVTARD-GGVPSLSDT--------------TDVEISVVDVNDNEPVFK 582
                  M+   + +   D G    ++DT              +  +I V   +  +P  +
Sbjct: 1644 KAGASVMTMSAVDIDDPDVGNNAVMTDTGVIRTRRMLDREKRSSYDIVVAATDGGDPPQE 1703

Query: 583  QQLYTANIMEDA----------LVGTSVSQ---VGATDA-------DVGLNGRIHYELDP 622
             ++    I++DA          +    +S+   +G+T A       D G+N ++ Y L+ 
Sbjct: 1704 GKVKVKVIVDDANDQHPQFTKRVFAAKISESAALGSTVATVSATDRDEGVNAKLKYSLEY 1763

Query: 623  KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDIN 681
            + +EE  F ID  +G I     LD E+   + LK    D G P   S T  + +++ D N
Sbjct: 1764 EAKEERPFRIDETTGEIILALTLDYETKRNYRLKVKVRDSGVPLSFSDTASLTVEVLDAN 1823

Query: 682  DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSL 737
            D  P FE    +  + E+  IG  +  +   DPD +  N         G++ N F L
Sbjct: 1824 DRAPRFEPLSYSAVVREDVDIGERLLRLEVTDPDSDSQNGGPFKFGISGNEKNLFEL 1880



 Score =  237 bits (581), Expect = 2e-60
 Identities = 206/760 (27%), Positives = 341/760 (44%), Gaps = 72/760 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + VLD N++ P+F+   Y  ++ EG+  GT +L + A D D G NA+V+Y          
Sbjct: 3   VRVLDGNNNDPIFQQSSYWVALPEGSPIGTELLRVTAEDLDSGSNADVKYQSS------- 55

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                            D+F +D  +G +  +    R K  +Y+  V A DQ  P     
Sbjct: 56  ----------------NDIFAVDETTGTITLQYQASRNK--KYSFTVTAFDQGKPSR--- 94

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           SS AT++V+I   +D+ P F + TY   + E+ ++     I +++A     GA   +RY 
Sbjct: 95  SSVATVYVSIHSFSDSPPVFRKSTYEKRIPENFALKRG--IVRVEALANGGGAGGELRYY 152

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD----GGSPSRSNTTQLLIN 246
           ++GG+ Q QF++D L+G++SL K LDYE+V SYRL IRA         P       +LI 
Sbjct: 153 LVGGDPQSQFNVDRLTGELSLKKPLDYEKVASYRLRIRAVQKTWRPNMPELPAEATVLIT 212

Query: 247 IRDVNDNAPRFY--TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           + D+NDNAPRF         S+ +  P G ++ +V AYD D G +A + Y + + D    
Sbjct: 213 VTDINDNAPRFAIPREPLVTSIHQFRPAGTTVTKVTAYDQDSGSHALVKYGLENAD---- 268

Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
              P TI P++G + T+ +L    +  Y  +VTATD   P    TA              
Sbjct: 269 -SFPFTITPQTGVIKTTAELRHFERDFYAFVVTATDSTPPFHKVTAN--IQLGDVNDNPP 325

Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITG-GNTRGRFSITSQNGRG 421
            F    Y+V + E+   G  +    A D D+  + R+ Y I    ++R     +     G
Sbjct: 326 LFAQPVYKVFVRENLQGGHVIGQFAARDPDKGANARVTYSIINFEDSRSDNLFSIHPFTG 385

Query: 422 LITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVF 479
           ++T    LD +   R++LT+ A D+G    S  A + I + D N++AP F +  +   + 
Sbjct: 386 VLTALSTLDREDLSRHILTIQAKDTGVPRMSGLAQIVIIVDDVNDHAPRFSSGSFHVEIP 445

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
            + P  + V    A D D G N  + YS+          +    F IN   G++  ++ L
Sbjct: 446 LNTPPDSRVFQARALDPDGGHNGLVRYSIIQ-------GNKQGYFSINHIDGSLFLDEKL 498

Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
              T+    + VT RD G P  S T D+ I  + V    P F    +  N+ E+   G  
Sbjct: 499 --TTLEPIDIKVT-RDMGQPERSSTADIRI-FIHVQAGPPQFLSSPFVGNVTENEPKGAF 554

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
           V  + A   D      + Y +     E G+F + P  G + T + LD E  + + +  +A
Sbjct: 555 VVHISAASLD-----PVMYSI-VSGNEAGNFRLHPGVGWLTTVRPLDNEKQSRYKIIVMA 608

Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVF---ESDCLTFYISENSPIGTTIGEIRAHDPDE 716
           +D     + S V V + + ++ND+ P F    +  +   + ++  +G+ +  I A D D 
Sbjct: 609 MD--LKNRVSKVEVIVNVLNVNDNKPKFVNIRNGIIEGNVLKDVAVGSRVMVIDAVDADR 666

Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756
             + ++ Y I+       FS+          ++  +D  Y
Sbjct: 667 --SDILSYRIEDEKARRYFSVNNEGVVTSTRVLRDLDSPY 704



 Score =  233 bits (571), Expect = 4e-59
 Identities = 212/710 (29%), Positives = 330/710 (46%), Gaps = 54/710 (7%)

Query: 138 VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQ 197
           V ++D N+N P F + +Y V++ E   +     + ++ A D D G+N+ ++Y     ++ 
Sbjct: 3   VRVLDGNNNDPIFQQSSYWVALPEGSPI--GTELLRVTAEDLDSGSNADVKYQ----SSN 56

Query: 198 MQFSIDSLSGDVSLVKTLDYEQVRS--YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP 255
             F++D  +G +    TL Y+  R+  Y   + A D G PSRS+   + ++I   +D+ P
Sbjct: 57  DIFAVDETTGTI----TLQYQASRNKKYSFTVTAFDQGKPSRSSVATVYVSIHSFSDSPP 112

Query: 256 RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315
            F  S +++ + EN  +   IVRV+A     G   EL Y +      G+      +D  +
Sbjct: 113 VFRKSTYEKRIPENFALKRGIVRVEALANGGGAGGELRYYLVG----GDPQSQFNVDRLT 168

Query: 316 GWVYTSGQLDRETQAKYQLLVTATD----GGDPPRSATATXXXXXXXXXXXXXXF-MPGQ 370
           G +     LD E  A Y+L + A         P   A AT              F +P +
Sbjct: 169 GELSLKKPLDYEKVASYRLRIRAVQKTWRPNMPELPAEATVLITVTDINDNAPRFAIPRE 228

Query: 371 YEV-ELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQ 427
             V  + +  P GT V  +TA D D  +   + Y +   ++   F+IT Q G  + T A+
Sbjct: 229 PLVTSIHQFRPAGTTVTKVTAYDQDSGSHALVKYGLENADS-FPFTITPQTG-VIKTTAE 286

Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
              F+++  Y   V+ATDS          I + D N+  P+F    Y   V E+   G  
Sbjct: 287 LRHFERD-FYAFVVTATDSTPPFHKVTANIQLGDVNDNPPLFAQPVYKVFVRENLQGGHV 345

Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
           +   +A D D G NA++TYS    I N   +  D  F I+P TG +T    LDRE +S +
Sbjct: 346 IGQFAARDPDKGANARVTYS----IINFEDSRSDNLFSIHPFTGVLTALSTLDREDLSRH 401

Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
           +LT+ A+D GVP +S    + I V DVND+ P F    +   I  +    + V Q  A D
Sbjct: 402 ILTIQAKDTGVPRMSGLAQIVIIVDDVNDHAPRFSSGSFHVEIPLNTPPDSRVFQARALD 461

Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
            D G NG + Y +  +  ++G F I+   G +  ++ L   ++   D+K V  D G P +
Sbjct: 462 PDGGHNGLVRYSI-IQGNKQGYFSINHIDGSLFLDEKL--TTLEPIDIK-VTRDMGQPER 517

Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
           SST  + I I  +   PP F S      ++EN P G  +  I A   D      V YSI 
Sbjct: 518 SSTADIRIFIH-VQAGPPQFLSSPFVGNVTENEPKGAFVVHISAASLDP-----VMYSIV 571

Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDV-RVEILVT- 785
            G+++ +F L    G     L T+  LD E  + +Y++++ A    L N V +VE++V  
Sbjct: 572 SGNEAGNFRLHPGVG----WLTTVRPLDNEK-QSRYKIIVMAMD--LKNRVSKVEVIVNV 624

Query: 786 -DVNDNAPVMKDFQ--IIFNNYKDCFPVGPFGRV-PAYDADVTDKLQYRI 831
            +VNDN P   + +  II  N      VG    V  A DAD +D L YRI
Sbjct: 625 LNVNDNKPKFVNIRNGIIEGNVLKDVAVGSRVMVIDAVDADRSDILSYRI 674



 Score =  225 bits (550), Expect = 1e-56
 Identities = 187/657 (28%), Positives = 285/657 (43%), Gaps = 50/657 (7%)

Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
           +++ + D N+N P F  S +  ++ E  PIG  ++RV A D D G NA++ Y  ++  + 
Sbjct: 1   VIVRVLDGNNNDPIFQQSSYWVALPEGSPIGTELLRVTAEDLDSGSNADVKYQSSNDIFA 60

Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
                   +D  +G +    Q  R    KY   VTA D G P RS+ AT           
Sbjct: 61  --------VDETTGTITLQYQASRNK--KYSFTVTAFDQGKPSRSSVATVYVSIHSFSDS 110

Query: 363 XXXFMPGQYEVELAEDEP--PGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420
              F    YE  + E+     G   V   A        L Y + GG+ + +F++    G 
Sbjct: 111 PPVFRKSTYEKRIPENFALKRGIVRVEALANGGGAGGELRYYLVGGDPQSQFNVDRLTGE 170

Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDT------AMVQINITDANNYAPVFE--NA 472
             +++ +PLD+++   Y L + A     R +       A V I +TD N+ AP F     
Sbjct: 171 --LSLKKPLDYEKVASYRLRIRAVQKTWRPNMPELPAEATVLITVTDINDNAPRFAIPRE 228

Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
           P   S+ +  P GTTV  V+A D D G +A + Y L +  S          F I PQTG 
Sbjct: 229 PLVTSIHQFRPAGTTVTKVTAYDQDSGSHALVKYGLENADSFP--------FTITPQTGV 280

Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592
           I T   L       Y   VTA D   P    T ++++   DVNDN P+F Q +Y   + E
Sbjct: 281 IKTTAELRHFERDFYAFVVTATDSTPPFHKVTANIQLG--DVNDNPPLFAQPVYKVFVRE 338

Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELD--PKDREEGSFVIDPASGVIRTNKALDRESV 650
           +   G  + Q  A D D G N R+ Y +      R +  F I P +GV+     LDRE +
Sbjct: 339 NLQGGHVIGQFAARDPDKGANARVTYSIINFEDSRSDNLFSIHPFTGVLTALSTLDREDL 398

Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710
           + H L   A D G P  S    + I ++D+ND  P F S      I  N+P  + + + R
Sbjct: 399 SRHILTIQAKDTGVPRMSGLAQIVIIVDDVNDHAPRFSSGSFHVEIPLNTPPDSRVFQAR 458

Query: 711 AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS--DKAELVTMVDLDYESPRKKYELVIR 768
           A DPD G N +V YSI  G+    FS+    GS     +L T+  +D +  R   +    
Sbjct: 459 ALDPDGGHNGLVRYSIIQGNKQGYFSINHIDGSLFLDEKLTTLEPIDIKVTRDMGQPERS 518

Query: 769 AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQ 828
           + +     D+R+ I    V    P       +  N  +  P G F  V    A   D + 
Sbjct: 519 STA-----DIRIFI---HVQAGPPQFLSSPFV-GNVTENEPKGAF--VVHISAASLDPVM 567

Query: 829 YRILSGNNANLILLNETTGSMTLSPQLNTNVP---KLATMEVSVTDGVNEIKAMMQL 882
           Y I+SGN A    L+   G +T    L+       K+  M + + + V++++ ++ +
Sbjct: 568 YSIVSGNEAGNFRLHPGVGWLTTVRPLDNEKQSRYKIIVMAMDLKNRVSKVEVIVNV 624



 Score =  121 bits (291), Expect = 3e-25
 Identities = 86/274 (31%), Positives = 129/274 (47%), Gaps = 23/274 (8%)

Query: 371  YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
            Y   + E+   G  V+T++A D D+ +       G N             G+I   + LD
Sbjct: 1635 YIGHVMENLKAGASVMTMSAVDIDDPD------VGNNA-------VMTDTGVIRTRRMLD 1681

Query: 431  FKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTV 488
             ++   Y + V+ATD G       V++ +   DAN+  P F    + A + E A +G+TV
Sbjct: 1682 REKRSSYDIVVAATDGGDPPQEGKVKVKVIVDDANDQHPQFTKRVFAAKISESAALGSTV 1741

Query: 489  LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
              VSATD D G+NA++ YSL  E      A  ++ F I+  TG I     LD ET   Y 
Sbjct: 1742 ATVSATDRDEGVNAKLKYSLEYE------AKEERPFRIDETTGEIILALTLDYETKRNYR 1795

Query: 549  LTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
            L V  RD GVP S SDT  + + V+D ND  P F+   Y+A + ED  +G  + ++  TD
Sbjct: 1796 LKVKVRDSGVPLSFSDTASLTVEVLDANDRAPRFEPLSYSAVVREDVDIGERLLRLEVTD 1855

Query: 608  ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641
             D        ++      E+  F +    GV++T
Sbjct: 1856 PDSDSQNGGPFKFGISGNEKNLFEL-TEDGVLKT 1888



 Score =  118 bits (285), Expect = 2e-24
 Identities = 75/226 (33%), Positives = 118/226 (52%), Gaps = 22/226 (9%)

Query: 571  VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630
            V DVNDN+P F  + Y  ++ME+   G SV  + A D D              D + G+ 
Sbjct: 1620 VGDVNDNKPRFPDEPYIGHVMENLKAGASVMTMSAVDID--------------DPDVGNN 1665

Query: 631  VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690
             +   +GVIRT + LDRE  +++D+   A DGG PPQ   V V + ++D ND  P F   
Sbjct: 1666 AVMTDTGVIRTRRMLDREKRSSYDIVVAATDGGDPPQEGKVKVKVIVDDANDQHPQFTKR 1725

Query: 691  CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK-GGDDSNSFSLETRQGSDKAELV 749
                 ISE++ +G+T+  + A D DEG NA + YS++    +   F ++   G    E++
Sbjct: 1726 VFAAKISESAALGSTVATVSATDRDEGVNAKLKYSLEYEAKEERPFRIDETTG----EII 1781

Query: 750  TMVDLDYESPRK-KYELVIRAASPPL-WND-VRVEILVTDVNDNAP 792
              + LDYE+ R  + ++ +R +  PL ++D   + + V D ND AP
Sbjct: 1782 LALTLDYETKRNYRLKVKVRDSGVPLSFSDTASLTVEVLDANDRAP 1827



 Score =  111 bits (266), Expect = 4e-22
 Identities = 80/280 (28%), Positives = 131/280 (46%), Gaps = 26/280 (9%)

Query: 142  DDNDNYPQFSEKTYTVSVDEDISVTDNPV-IAKIKATDADVGANSAIRYAIIGGNTQMQF 200
            D NDN P+F ++ Y   V E++    + + ++ +   D DVG N+ +             
Sbjct: 1622 DVNDNKPRFPDEPYIGHVMENLKAGASVMTMSAVDIDDPDVGNNAVM------------- 1668

Query: 201  SIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260
               + +G +   + LD E+  SY +V+ A DGG P +    ++ + + D ND  P+F   
Sbjct: 1669 ---TDTGVIRTRRMLDREKRSSYDIVVAATDGGDPPQEGKVKVKVIVDDANDQHPQFTKR 1725

Query: 261  LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT 320
            +F   +SE+  +G ++  V A D DEGVNA+L Y++   +Y    + P  ID  +G +  
Sbjct: 1726 VFAAKISESAALGSTVATVSATDRDEGVNAKLKYSL---EYEAKEERPFRIDETTGEIIL 1782

Query: 321  SGQLDRETQAKYQLLVTATDGGDP-PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE 379
            +  LD ET+  Y+L V   D G P   S TA+              F P  Y   + ED 
Sbjct: 1783 ALTLDYETKRNYRLKVKVRDSGVPLSFSDTASLTVEVLDANDRAPRFEPLSYSAVVREDV 1842

Query: 380  PPGTPVVTLTATDADEDNR----LHYEITGGNTRGRFSIT 415
              G  ++ L  TD D D++      + I+ GN +  F +T
Sbjct: 1843 DIGERLLRLEVTDPDSDSQNGGPFKFGIS-GNEKNLFELT 1881



 Score = 86.2 bits (204), Expect = 1e-14
 Identities = 53/189 (28%), Positives = 92/189 (48%), Gaps = 20/189 (10%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ V D ND  P F  + + A + E A+ G+TV T+ ATD+D G NA+++Y++E    + 
Sbjct: 1709 KVIVDDANDQHPQFTKRVFAAKISESAALGSTVATVSATDRDEGVNAKLKYSLEYEAKE- 1767

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                             +  FRID  +G ++   +LD E    Y + VK  D   P+S  
Sbjct: 1768 -----------------ERPFRIDETTGEIILALTLDYETKRNYRLKVKVRDSGVPLS-- 1808

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             S TA++ V ++D ND  P+F   +Y+  V ED+ + +  +  ++   D+D       ++
Sbjct: 1809 FSDTASLTVEVLDANDRAPRFEPLSYSAVVREDVDIGERLLRLEVTDPDSDSQNGGPFKF 1868

Query: 190  AIIGGNTQM 198
             I G    +
Sbjct: 1869 GISGNEKNL 1877


>UniRef50_Q4SVN1 Cluster: Chromosome 1 SCAF13750, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 1 SCAF13750, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 728

 Score =  287 bits (703), Expect = 4e-75
 Identities = 207/690 (30%), Positives = 327/690 (47%), Gaps = 34/690 (4%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F  + ++G L+    +DRE++   TV  K T     +         I V I D NDN P 
Sbjct: 48  FEANSKTGDLVVNERIDREELCPNTV--KCTLNLEAILSDPVVLHRIEVVISDLNDNAPV 105

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD- 208
           F EK+Y++++ E  S T    +  + A DAD G+NS   Y +   N+   FS+D  SGD 
Sbjct: 106 FLEKSYSLNISE-WSPTGERFLLPL-AVDADTGSNSVTTYRL---NSNEYFSLDVQSGDD 160

Query: 209 ------VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLF 262
                 + L+++LD E+    +L + A DGG P ++ +  + +N+ D NDN P F  SL+
Sbjct: 161 QSASAELVLLRSLDREKQAVLKLTLTALDGGKPPKTGSLSIDVNVLDANDNTPTFSKSLY 220

Query: 263 QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322
           +  V+EN P G  ++++ A D DEG N  + Y+   +      D+   ID  SG V    
Sbjct: 221 KARVNENAPAGSPVIQLSATDLDEGDNGRVVYSFVKRGNFNPADV-FVIDAESGEVTVKA 279

Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382
            LD ETQ+ +++ V A D G  PRSA +                        + ED   G
Sbjct: 280 ALDYETQSAFEVHVQARDKGFSPRSANSKLLVEVVDVNDNAPEIAVTSLVNPVKEDAEIG 339

Query: 383 TPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440
           + V  +T TD D  ++ +   EI  G+   +     +N   L+ V  PLD ++   Y +T
Sbjct: 340 SAVALVTVTDKDSGKNGKTRTEIV-GSVPFKLLSNYKNYYSLV-VDGPLDREKCSSYSIT 397

Query: 441 VSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498
           ++A D G    S T +V +++ D N+ AP F +      V E++P+G  +  ++ATD D 
Sbjct: 398 ITAADEGSPPLSSTILVIVHVADVNDNAPAFSSPEVNIYVKENSPVGALIHTITATDPDK 457

Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558
             NA +TYS+     +           IN +TG I + +  D E +  +   V A D GV
Sbjct: 458 EENAIVTYSVMH--GSRITQQKTWLISINSETGDIVSLQSFDYEELKTFQFQVQATDSGV 515

Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618
           P LS TT ++I + DVNDN P+FK+ +   ++ E++ VG ++  +   D D   N ++ Y
Sbjct: 516 PPLSSTTVIQIHISDVNDNAPLFKEPVVNVHVKENSPVGITILTITTADLDREENAKVTY 575

Query: 619 ELDP----KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674
            L            +  I+  +G I   ++ D E V T   +  A D G PP SS V V+
Sbjct: 576 SLIDGLFNSISVRSAVNINSDTGDITILQSFDYEEVKTFQFQVQATDSGVPPLSSNVSVN 635

Query: 675 IKIEDINDSPPVF------ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
           + I D ND+ P             +  I  ++  G  + +IRA D D G NA++ Y +  
Sbjct: 636 VFILDENDNNPAILAPYSEHGSVNSESIPYSAEAGYFVAKIRAVDSDSGYNALLSYHLSE 695

Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYES 758
              +N F + T  G  + +   M D D +S
Sbjct: 696 PKGNNLFRMGTSTGEIRTKR-RMSDNDLKS 724



 Score =  276 bits (677), Expect = 6e-72
 Identities = 200/676 (29%), Positives = 324/676 (47%), Gaps = 52/676 (7%)

Query: 1   MSVPFCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVE 59
           +S P  +H+ ++ + D ND++PVF  + Y  ++ E + +G   L   A D D G N+   
Sbjct: 83  LSDPVVLHRIEVVISDLNDNAPVFLEKSYSLNISEWSPTGERFLLPLAVDADTGSNSVTT 142

Query: 60  YTI---ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVL 116
           Y +   E  + D  + +D                     S  L+   SLDREK A   + 
Sbjct: 143 YRLNSNEYFSLDVQSGDD------------------QSASAELVLLRSLDREKQAVLKLT 184

Query: 117 VKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKA 176
           + A D   P     + + +I VN++D NDN P FS+  Y   V+E+ +   +PVI ++ A
Sbjct: 185 LTALDGGKPPK---TGSLSIDVNVLDANDNTPTFSKSLYKARVNEN-APAGSPVI-QLSA 239

Query: 177 TDADVGANSAIRYAII---GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233
           TD D G N  + Y+ +     N    F ID+ SG+V++   LDYE   ++ + ++A+D G
Sbjct: 240 TDLDEGDNGRVVYSFVKRGNFNPADVFVIDAESGEVTVKAALDYETQSAFEVHVQARDKG 299

Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293
              RS  ++LL+ + DVNDNAP    +     V E+  IG ++  V   D D G N +  
Sbjct: 300 FSPRSANSKLLVEVVDVNDNAPEIAVTSLVNPVKEDAEIGSAVALVTVTDKDSGKNGK-- 357

Query: 294 YTMTDKDYTGNVDLPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352
              T  +  G+V   +  + ++ + +   G LDRE  + Y + +TA D G PP S+T   
Sbjct: 358 ---TRTEIVGSVPFKLLSNYKNYYSLVVDGPLDREKCSSYSITITAADEGSPPLSSTILV 414

Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD-EDNRL-HYEITGGN--T 408
                        F   +  + + E+ P G  + T+TATD D E+N +  Y +  G+  T
Sbjct: 415 IVHVADVNDNAPAFSSPEVNIYVKENSPVGALIHTITATDPDKEENAIVTYSVMHGSRIT 474

Query: 409 RGRFSITSQNGR-GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNY 465
           + +  + S N   G I   Q  D+++ + +   V ATDSG    S T ++QI+I+D N+ 
Sbjct: 475 QQKTWLISINSETGDIVSLQSFDYEELKTFQFQVQATDSGVPPLSSTTVIQIHISDVNDN 534

Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525
           AP+F+       V E++P+G T+L ++  D D   NA++TYSL   + N           
Sbjct: 535 APLFKEPVVNVHVKENSPVGITILTITTADLDREENAKVTYSLIDGLFNSISVR--SAVN 592

Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF---- 581
           IN  TG IT  +  D E +  +   V A D GVP LS    V + ++D NDN P      
Sbjct: 593 INSDTGDITILQSFDYEEVKTFQFQVQATDSGVPPLSSNVSVNVFILDENDNNPAILAPY 652

Query: 582 --KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639
                + + +I   A  G  V+++ A D+D G N  + Y L  + +    F +  ++G I
Sbjct: 653 SEHGSVNSESIPYSAEAGYFVAKIRAVDSDSGYNALLSYHLS-EPKGNNLFRMGTSTGEI 711

Query: 640 RTNKALDRESVATHDL 655
           RT + +    + +H L
Sbjct: 712 RTKRRMSDNDLKSHPL 727



 Score =  266 bits (653), Expect = 5e-69
 Identities = 199/693 (28%), Positives = 330/693 (47%), Gaps = 36/693 (5%)

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDGGS-PSRSNTTQLLINI 247
           I+ G ++  F  +S +GD+ + + +D E++   + +  +  +   S P   +  +++I+ 
Sbjct: 39  IVSGYSKKYFEANSKTGDLVVNERIDREELCPNTVKCTLNLEAILSDPVVLHRIEVVIS- 97

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            D+NDNAP F    +  ++SE  P G   +   A DAD G N+  TY +   +Y  ++D+
Sbjct: 98  -DLNDNAPVFLEKSYSLNISEWSPTGERFLLPLAVDADTGSNSVTTYRLNSNEYF-SLDV 155

Query: 308 PITIDPR-SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
               D   S  +     LDRE QA  +L +TA DGG PP++ + +              F
Sbjct: 156 QSGDDQSASAELVLLRSLDREKQAVLKLTLTALDGGKPPKTGSLSIDVNVLDANDNTPTF 215

Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADE-DN-RLHYE-ITGGNTRGRFSITSQNGRGLI 423
               Y+  + E+ P G+PV+ L+ATD DE DN R+ Y  +  GN             G +
Sbjct: 216 SKSLYKARVNENAPAGSPVIQLSATDLDEGDNGRVVYSFVKRGNFNPADVFVIDAESGEV 275

Query: 424 TVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
           TV   LD++ +  + + V A D G   RS  + + + + D N+ AP          V ED
Sbjct: 276 TVKAALDYETQSAFEVHVQARDKGFSPRSANSKLLVEVVDVNDNAPEIAVTSLVNPVKED 335

Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
           A IG+ V +V+ TD D G N +    +   +  + ++++   +       ++  +  LDR
Sbjct: 336 AEIGSAVALVTVTDKDSGKNGKTRTEIVGSVPFKLLSNYKNYY-------SLVVDGPLDR 388

Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
           E  S Y +T+TA D G P LS T  V + V DVNDN P F        + E++ VG  + 
Sbjct: 389 EKCSSYSITITAADEGSPPLSSTILVIVHVADVNDNAPAFSSPEVNIYVKENSPVGALIH 448

Query: 602 QVGATDADVGLNGRIHYELDPKDR--EEGSFVI--DPASGVIRTNKALDRESVATHDLKA 657
            + ATD D   N  + Y +    R  ++ +++I  +  +G I + ++ D E + T   + 
Sbjct: 449 TITATDPDKEENAIVTYSVMHGSRITQQKTWLISINSETGDIVSLQSFDYEELKTFQFQV 508

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
            A D G PP SST ++ I I D+ND+ P+F+   +  ++ ENSP+G TI  I   D D  
Sbjct: 509 QATDSGVPPLSSTTVIQIHISDVNDNAPLFKEPVVNVHVKENSPVGITILTITTADLDRE 568

Query: 718 PNAVVHYS-IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PP 773
            NA V YS I G  +S S        SD  ++  +   DYE   K ++  ++A     PP
Sbjct: 569 ENAKVTYSLIDGLFNSISVRSAVNINSDTGDITILQSFDYEEV-KTFQFQVQATDSGVPP 627

Query: 774 LWNDVRVEILVTDVNDNAP-VMKDFQIIFNNYKDCFP----VGPF-GRVPAYDAD--VTD 825
           L ++V V + + D NDN P ++  +    +   +  P     G F  ++ A D+D     
Sbjct: 628 LSSNVSVNVFILDENDNNPAILAPYSEHGSVNSESIPYSAEAGYFVAKIRAVDSDSGYNA 687

Query: 826 KLQYRILSGNNANLILLNETTGSMTLSPQLNTN 858
            L Y +      NL  +  +TG +    +++ N
Sbjct: 688 LLSYHLSEPKGNNLFRMGTSTGEIRTKRRMSDN 720



 Score =  226 bits (553), Expect = 6e-57
 Identities = 162/546 (29%), Positives = 274/546 (50%), Gaps = 32/546 (5%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNG---- 419
           F+   Y + ++E  P G   +   A DAD  +     Y +   N+   FS+  Q+G    
Sbjct: 106 FLEKSYSLNISEWSPTGERFLLPLAVDADTGSNSVTTYRL---NSNEYFSLDVQSGDDQS 162

Query: 420 -RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTA 476
               + + + LD +++    LT++A D G   ++ +  + +N+ DAN+  P F  + Y A
Sbjct: 163 ASAELVLLRSLDREKQAVLKLTLTALDGGKPPKTGSLSIDVNVLDANDNTPTFSKSLYKA 222

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
            V E+AP G+ V+ +SATD D G N ++ YS      N   A     FVI+ ++G +T  
Sbjct: 223 RVNENAPAGSPVIQLSATDLDEGDNGRVVYSFVKR-GNFNPA---DVFVIDAESGEVTVK 278

Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
             LD ET S + + V ARD G    S  + + + VVDVNDN P          + EDA +
Sbjct: 279 AALDYETQSAFEVHVQARDKGFSPRSANSKLLVEVVDVNDNAPEIAVTSLVNPVKEDAEI 338

Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
           G++V+ V  TD D G NG+   E+      +          ++  +  LDRE  +++ + 
Sbjct: 339 GSAVALVTVTDKDSGKNGKTRTEIVGSVPFKLLSNYKNYYSLV-VDGPLDREKCSSYSIT 397

Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
             A D G+PP SST++V + + D+ND+ P F S  +  Y+ ENSP+G  I  I A DPD+
Sbjct: 398 ITAADEGSPPLSSTILVIVHVADVNDNAPAFSSPEVNIYVKENSPVGALIHTITATDPDK 457

Query: 717 GPNAVVHYSIKGGDD-SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---P 772
             NA+V YS+  G   +   +      S+  ++V++   DYE   K ++  ++A     P
Sbjct: 458 EENAIVTYSVMHGSRITQQKTWLISINSETGDIVSLQSFDYEE-LKTFQFQVQATDSGVP 516

Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTD--KLQY 829
           PL +   ++I ++DVNDNAP+ K+  ++  + K+  PVG     +   D D  +  K+ Y
Sbjct: 517 PLSSTTVIQIHISDVNDNAPLFKE-PVVNVHVKENSPVGITILTITTADLDREENAKVTY 575

Query: 830 RILSG--NNANL---ILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLS 883
            ++ G  N+ ++   + +N  TG +T+    +    K    +V  TD GV  + + + ++
Sbjct: 576 SLIDGLFNSISVRSAVNINSDTGDITILQSFDYEEVKTFQFQVQATDSGVPPLSSNVSVN 635

Query: 884 VRLITE 889
           V ++ E
Sbjct: 636 VFILDE 641



 Score =  120 bits (289), Expect = 6e-25
 Identities = 96/328 (29%), Positives = 157/328 (47%), Gaps = 25/328 (7%)

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
           SV E+   GT   VV      + +N +    L +   N    +  + F  N +TG +  N
Sbjct: 7   SVSEEVDKGT---VVGNLAKHLNVNIR---DLHARNLNIVSGYSKKYFEANSKTGDLVVN 60

Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTT---DVEISVVDVNDNEPVFKQQLYTANIMED 593
           + +DRE +    +  T     +  LSD      +E+ + D+NDN PVF ++ Y+ NI E 
Sbjct: 61  ERIDREELCPNTVKCTLNLEAI--LSDPVVLHRIEVVISDLNDNAPVFLEKSYSLNISEW 118

Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKD---REEGSFVIDPASGVIRTNKALDRESV 650
           +  G       A DAD G N    Y L+  +    +  S     AS  +   ++LDRE  
Sbjct: 119 SPTGERFLLPLAVDADTGSNSVTTYRLNSNEYFSLDVQSGDDQSASAELVLLRSLDREKQ 178

Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710
           A   L   A+DGG PP++ ++ + + + D ND+ P F        ++EN+P G+ + ++ 
Sbjct: 179 AVLKLTLTALDGGKPPKTGSLSIDVNVLDANDNTPTFSKSLYKARVNENAPAGSPVIQLS 238

Query: 711 AHDPDEGPNAVVHYS-IKGG--DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
           A D DEG N  V YS +K G  + ++ F ++   G    E+     LDYE+ +  +E+ +
Sbjct: 239 ATDLDEGDNGRVVYSFVKRGNFNPADVFVIDAESG----EVTVKAALDYET-QSAFEVHV 293

Query: 768 RAAS---PPLWNDVRVEILVTDVNDNAP 792
           +A      P   + ++ + V DVNDNAP
Sbjct: 294 QARDKGFSPRSANSKLLVEVVDVNDNAP 321



 Score = 81.0 bits (191), Expect = 4e-13
 Identities = 61/221 (27%), Positives = 104/221 (47%), Gaps = 21/221 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           QI++ D ND++P+F+       V+E +  G T+LT+   D D  +NA+V Y++     D 
Sbjct: 525 QIHISDVNDNAPLFKEPVVNVHVKENSPVGITILTITTADLDREENAKVTYSL----IDG 580

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
           L               V+    I+  +G +    S D E+V  +   V+ATD   P    
Sbjct: 581 L----------FNSISVRSAVNINSDTGDITILQSFDYEEVKTFQFQVQATDSGVPP--- 627

Query: 130 LSSTATIHVNIIDDNDNYPQ----FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
           LSS  +++V I+D+NDN P     +SE     S     S      +AKI+A D+D G N+
Sbjct: 628 LSSNVSVNVFILDENDNNPAILAPYSEHGSVNSESIPYSAEAGYFVAKIRAVDSDSGYNA 687

Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLV 226
            + Y +        F + + +G++   + +    ++S+ LV
Sbjct: 688 LLSYHLSEPKGNNLFRMGTSTGEIRTKRRMSDNDLKSHPLV 728


>UniRef50_Q19319 Cluster: Cadherin-4 precursor; n=1; Caenorhabditis
            elegans|Rep: Cadherin-4 precursor - Caenorhabditis
            elegans
          Length = 4307

 Score =  285 bits (699), Expect = 1e-74
 Identities = 317/1243 (25%), Positives = 537/1243 (43%), Gaps = 121/1243 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +++ D ND++P F       ++ E A+ GT+V    A D+D   +  + ++  LV     
Sbjct: 2679 VDIGDVNDNAPAFHGDYERFTISEDAAVGTSVTIFSAMDRDDSPSGRIRFS--LVEE--- 2733

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            NP                 F ++  SG L   + LDREK+  Y ++ +ATD+    +D L
Sbjct: 2734 NP----------------YFDLNENSGWLTVASQLDREKIDHYKLIARATDEGGFNTD-L 2776

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
              T  +     D ND+ PQF ++ + +    D+ +     I      D D+  N+  ++ 
Sbjct: 2777 PFTIVVS----DVNDSPPQFEKEEFNI----DLHLPSTSPILHFSIKDDDLSPNNVSQFF 2828

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            I  GN +  F IDS + D+ L +    E    Y+L + A DG   +   +T++ IN++  
Sbjct: 2829 IPKGNEEGVFWIDS-NNDLLLKRPEIVENKMQYQLKVTAFDGVFET---STKVKINLKSS 2884

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
             D+  R   +     ++EN   G  ++   +      +   +T+ ++D D  GNV     
Sbjct: 2885 KDSDIRCPEANKTVILAENSKKGTVVLGESSL-----LGPNVTFKLSDND--GNV---FV 2934

Query: 311  IDPRSGWVYT--SGQLDRETQAKYQL-LVTATDGGDPPRSA-TATXXXXXXXXXXXXXXF 366
            ++ R+G V    S Q+D E   + +   +T  D  +  +   T                 
Sbjct: 2935 VNFRNGIVKVKESDQIDYEKNQQLEFHRLTIQDNSEVCKELITVVIENLNDNRPKIIEKL 2994

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
            +    +  L   E     +  + A DAD D  + + +   +  G F I   NG  ++TV 
Sbjct: 2995 LKVSIDENLPTSEDARQYITRIVAEDADFDE-IKFRMVD-DFGGLFQIDDING--VVTVV 3050

Query: 427  QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
            +PLD +    + LTV A+D G   D A + + + D N+ AP FE + Y+  V E   IG 
Sbjct: 3051 KPLDSEILGFFNLTVVASD-GEFEDKATILVTVIDQNDNAPTFEKSTYSMKVMESESIGY 3109

Query: 487  TVLVVSATDSDVGINAQITYSLS-SEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETM 544
             +    A+  D   N  I Y L  S++++         FV +N QTG +T  K LD ET+
Sbjct: 3110 ELAHFRASGGDQ--NETIEYYLKPSDVTS---------FVNLNAQTGILTLAKPLDFETL 3158

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
            S   LTV A+D GVP L     VEISV+D NDN P F+++ Y   + E++  G  V  V 
Sbjct: 3159 SALKLTVVAKDSGVPPLETEAQVEISVMDENDNAPKFEKEKYVGKVKENSKSGEKVLTVK 3218

Query: 605  ATDADVGLNGRIHYELD-----PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
            A D D    G + YEL+       D     F I+ ++G +  ++++D E +  ++LK +A
Sbjct: 3219 ALDVDSEHFGAVSYELEIVSETTTDTPVLPFAIN-SNGDVLISQSIDYEKIKKYNLKVIA 3277

Query: 660  IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
             DGG PP  S  ++ I +ED ND  P F+   +T  + E   IG  + +    D D GP 
Sbjct: 3278 KDGGRPPLRSEALLEIHVEDENDHAPTFDDCNMTALVQEGEAIGHRLLKFSVSDLD-GPK 3336

Query: 720  AVVHYSIK-GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDV 778
                ++++  GD + SF +     ++K EL+T   L+Y    K    VI         D 
Sbjct: 3337 NGAPFTVEIQGDGAKSFKV-----NEKLELLTAKKLEYRKKDKYLLTVIAKDVKGKTTDC 3391

Query: 779  RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK---LQYRILSGN 835
             + I +   + +AP MK  +I  N  ++  P G  GR+ A D D  D+   L++ ++ G+
Sbjct: 3392 PLTIFIRQTSRHAPTMKPMKIQINTLQNELPEGIIGRLKASDEDEEDQNGLLRFGLVEGS 3451

Query: 836  -NANLILLNETTGSMTLSPQLNTN--------VPKLATMEVSVTDGVNEIKAMMQLSVRL 886
              +    + E+  +       NT            L T  V+VTD      + +++ V  
Sbjct: 3452 IQSPRAQVQESRSTHLFRVDPNTGDIWSDHSITQGLHTFNVTVTDSKFNTVSYVEVHVTS 3511

Query: 887  ITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKE-NIYIFSVQDDTDVTGN 945
            I  +++ +++++R+  M+ ++F+   +  F   ++  +    + +I + SVQ        
Sbjct: 3512 IDNDVIDHAVSIRIRSMSVDEFMRKHVKEFRRIISHHLNLNDDSSIQLISVQAVPSTESE 3571

Query: 946  ILNVSFSARRPDAEV---GVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNIC 1002
                S      D E+      G    +  P H+  R+      +   +          +C
Sbjct: 3572 --RRSRRNSMEDVEILMTAQRGLGRGYLKPDHIYSRLKNDFQNMNDQSQRMRYQLITEMC 3629

Query: 1003 VHEPCLNFEECLTVLKFGNASGF-VNSDSVLFRPIYPVTSFTCQCPEGFTGVNCE---TI 1058
                CL   EC  V++    S   V++D   F   +   S  C CP+GF G  CE     
Sbjct: 3630 TTGVCLR-GECREVIELIEDSWTKVSTDDFSFVSPFHSRSAQCLCPDGFGGKRCEVETNQ 3688

Query: 1059 LTKASCEVDG--DGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCELRARSFPVSS-- 1114
              K+ CE       S+  S  +CV     G+    CS+ +      C L      V    
Sbjct: 3689 CAKSPCEQWQLCIPSVHNSTYECVCPL--GMEGDKCSVPSCQNDGKC-LEEAELSVGGDG 3745

Query: 1115 -FLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRGGGPGLR 1173
             F      +   R+ L+++  T T +G+++++     + DF  L LV+      G P   
Sbjct: 3746 YFEISLSNEIETRMELEIELKTTTHNGIIMWS---RGKRDFHMLRLVN------GTP--E 3794

Query: 1174 FSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCD 1216
            + ++ G G   +T + +V DG WH + I    R   M +DD D
Sbjct: 3795 YHWNAGTGTGIVTSKTSVVDGQWHRIAISRRQRRTRMTVDDED 3837



 Score =  238 bits (583), Expect = 1e-60
 Identities = 248/916 (27%), Positives = 415/916 (45%), Gaps = 93/916 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEY--TIELVTAD 68
            I +LD NDH+PVF  +    +       G  ++ + ATDQD G+N ++ Y  T EL    
Sbjct: 480  IEILDSNDHAPVFSAKWMRQTPIVIGKPGDVLVKVDATDQDEGENGKIVYKFTSELPLEI 539

Query: 69   TLNPEDAXXXX--XXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
              N  +                V+ ID   G  L+R S     +  Y    K   +  P+
Sbjct: 540  NANTGEITLVEVPKKGNSWPATVWAID--LGLPLSRMS--ALNLMFYKNGTKIPAKPKPI 595

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
              + S           +N + P FS     V V ED  +    V+AK++A D D G N  
Sbjct: 596  IIQES-----------ENKHSPVFSSFPEIVEVTEDAPI--GTVVAKLQANDEDTGYNGF 642

Query: 187  IRYAI--IGGNTQMQFSIDSLSGDVSL-----------VKTLDYE---------QVRSYR 224
            IRY I  I G++    ++D  SG++++           ++ LD +          + +++
Sbjct: 643  IRYVIHDIAGSSHEVLTVDEQSGEITVASDLSKLMKEKLEVLDVQVHYIKHVTSNISNFQ 702

Query: 225  LVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA 284
            L + A D G+P +S+   + + I+DVN+++P+F    +   +SEN   G  I +V A D 
Sbjct: 703  LKVSAIDAGTPVKSSVKTMKLRIKDVNNHSPQFDEVSYYLRISENEKPGKDIFKVTANDF 762

Query: 285  DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP 344
            D G N ++ +++ +     +V   I+ID ++G V     LDRE Q  +   + A+D G P
Sbjct: 763  DGGNNGKIKFSLGNNQEKSSV---ISIDAKTGIVKLLKSLDREDQDVHTFAIIASDEGFP 819

Query: 345  PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT 404
             R +                  +       + ED P G  V  + A D D       +  
Sbjct: 820  MRVSVTNLTISVEDVNDNPPKCVVQHSRARIPEDLPHGAFVSCMAAFDEDIGQNSKLKFL 879

Query: 405  GGNTRGRFSITSQNGRGLITVAQ-PLDFKQERRYVLTVSATDSGG--RSDTAMVQINITD 461
              + +  F I   +G   I   + PLD+ +   + L++   D G    S +  + + + D
Sbjct: 880  LNSEKVPFRIDHHSGCIFIHAPEYPLDYHKTPFFNLSIEVADHGDPILSTSCHLHVELVD 939

Query: 462  -ANNYAPV-FENAPYTASVFEDAPIGTTVLVVSA--TDSDVGINAQ-ITYSLSSEISNEA 516
             A+N+  + F++    ASV+E++ IGT V+++ A  T  +  + A+ + Y +   I  + 
Sbjct: 940  IAHNHLAIEFDDVAKEASVYENSEIGTEVIMIEAKETGDEQKVKAENLEYRI---IGGDG 996

Query: 517  VAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV-----PSLSDTTDVEISV 571
              H    F I+ Q G + T  LLDRET S Y +TV ARD        P   D   V I +
Sbjct: 997  WPH----FSID-QKGTVRTTHLLDRETKSAYWITVEARDSKTDLYKDPRRRDVLHVFIRI 1051

Query: 572  VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN---GRIHYELDPKDREEG 628
            +D ND+ PV K+ +Y A++ E++     + +V ATDAD   N     + ++++  D  + 
Sbjct: 1052 LDRNDHRPVAKKPMYIASVAENSPANVVIVKVEATDADDVDNDAAAPLMFKIERGD-PQS 1110

Query: 629  SFVIDPASGVIRTN--KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686
             F ID  SG I T+  + LDRE  + H+L     DGG P   S VIV + + D ND+ P 
Sbjct: 1111 FFRIDLTSGYITTSGIRRLDREKQSEHELWVSICDGGEPQLCSNVIVIVNVLDENDNSPT 1170

Query: 687  FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD-------DSNSFSLET 739
            F +  +  Y S  S     +  I A D DEG NA + Y+I  GD       + N  + E 
Sbjct: 1171 F-TQAIHHY-SVRSKFAGKLCRIFAVDADEGENARLTYNITEGDARFSIDNNGNIIASEA 1228

Query: 740  RQGSDKAELVTMVDLDYESPRKKYEL--VIRAASPPLWNDVRVEILVTDVNDNAPVMKDF 797
              G D++  +T+   D+ +P +++    V+  A+       + +    +++       D+
Sbjct: 1229 IHG-DESYALTVQATDHGTPGQQFAATRVVLTANSAGQKPRKSKNSPPEISGK---KSDY 1284

Query: 798  QIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
             I  +   D   VG   G++ A DAD  D+L + I SG+  ++  + + TG + L+ ++ 
Sbjct: 1285 VIPIS---DADQVGLTVGKLEASDAD-GDELWWSISSGDPDSVFDVRQDTGQLLLAKKVE 1340

Query: 857  TNVPKLATMEVSVTDG 872
                    + +SVTDG
Sbjct: 1341 LLKRGELRLNISVTDG 1356



 Score =  229 bits (561), Expect = 6e-58
 Identities = 227/809 (28%), Positives = 352/809 (43%), Gaps = 81/809 (10%)

Query: 17   NDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI--------ELVTAD 68
            N HSPVF        V E A  GT V  L+A D+D G N  + Y I        E++T D
Sbjct: 602  NKHSPVFSSFPEIVEVTEDAPIGTVVAKLQANDEDTGYNGFIRYVIHDIAGSSHEVLTVD 661

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
              + E            +++   +       +   +     ++ + + V A D  +PV  
Sbjct: 662  EQSGE--ITVASDLSKLMKEKLEVLDVQVHYIKHVT---SNISNFQLKVSAIDAGTPVK- 715

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
              SS  T+ + I D N++ PQF E +Y + + E+     +  I K+ A D D G N  I+
Sbjct: 716  --SSVKTMKLRIKDVNNHSPQFDEVSYYLRISENEKPGKD--IFKVTANDFDGGNNGKIK 771

Query: 189  YAIIGGNTQMQ---FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
            +++  GN Q +    SID+ +G V L+K+LD E    +   I A D G P R + T L I
Sbjct: 772  FSL--GNNQEKSSVISIDAKTGIVKLLKSLDREDQDVHTFAIIASDEGFPMRVSVTNLTI 829

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
            ++ DVNDN P+      +  + E++P G  +  + A+D D G N++L + +  +      
Sbjct: 830  SVEDVNDNPPKCVVQHSRARIPEDLPHGAFVSCMAAFDEDIGQNSKLKFLLNSE------ 883

Query: 306  DLPITIDPRSGWVYTSG---QLDRETQAKYQLLVTATDGGDPPRSATA--TXXXXXXXXX 360
             +P  ID  SG ++       LD      + L +   D GDP  S +             
Sbjct: 884  KVPFRIDHHSGCIFIHAPEYPLDYHKTPFFNLSIEVADHGDPILSTSCHLHVELVDIAHN 943

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR-----LHYEITGGNTRGRFSIT 415
                 F     E  + E+   GT V+ + A +  ++ +     L Y I GG+    FSI 
Sbjct: 944  HLAIEFDDVAKEASVYENSEIGTEVIMIEAKETGDEQKVKAENLEYRIIGGDGWPHFSI- 1002

Query: 416  SQNGRGLITVAQPLDFKQERRYVLTVSATDS-------GGRSDTAMVQINITDANNYAPV 468
              + +G +     LD + +  Y +TV A DS         R D   V I I D N++ PV
Sbjct: 1003 --DQKGTVRTTHLLDRETKSAYWITVEARDSKTDLYKDPRRRDVLHVFIRILDRNDHRPV 1060

Query: 469  FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528
             +   Y ASV E++P    ++ V ATD+D  ++      L  +I           F I+ 
Sbjct: 1061 AKKPMYIASVAENSPANVVIVKVEATDAD-DVDNDAAAPLMFKIER---GDPQSFFRIDL 1116

Query: 529  QTGAITTN--KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586
             +G ITT+  + LDRE  S + L V+  DGG P L     V ++V+D NDN P F Q ++
Sbjct: 1117 TSGYITTSGIRRLDREKQSEHELWVSICDGGEPQLCSNVIVIVNVLDENDNSPTFTQAIH 1176

Query: 587  TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646
              ++      G  + ++ A DAD G N R+ Y +   D     F ID    +I +     
Sbjct: 1177 HYSV-RSKFAG-KLCRIFAVDADEGENARLTYNITEGD---ARFSIDNNGNIIASEAIHG 1231

Query: 647  RESVATHDLKAVAIDGGTPPQ--SSTVIVHI------KIEDINDSPPVFESDCLTFY--I 696
             ES A   L   A D GTP Q  ++T +V        K     +SPP        +   I
Sbjct: 1232 DESYA---LTVQATDHGTPGQQFAATRVVLTANSAGQKPRKSKNSPPEISGKKSDYVIPI 1288

Query: 697  SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756
            S+   +G T+G++ A D D      + +SI  GD  + F  + RQ + +  L   V+L  
Sbjct: 1289 SDADQVGLTVGKLEASDAD---GDELWWSISSGDPDSVF--DVRQDTGQLLLAKKVEL-- 1341

Query: 757  ESPRKKYELVIRAASPPLWNDVRVEILVT 785
               R +  L I       W+   V I V+
Sbjct: 1342 -LKRGELRLNISVTDGQAWDHSTVIIQVS 1369



 Score =  214 bits (523), Expect = 3e-53
 Identities = 200/792 (25%), Positives = 353/792 (44%), Gaps = 80/792 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            ++V+D ND  P F +  Y  S+ E A  G TV+ + ATD D  +N  +EY++       L
Sbjct: 2472 LSVIDINDKPPFFVLPFYSTSISESAKEGDTVMMVSATDDD--ENDTIEYSL-------L 2522

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +  ++              F +  R G +     L+ +     ++ +KATD A+P     
Sbjct: 2523 DGSES------------QFFSVHPRQGTITVAKKLEHKAGVTLSLTIKATDSANPPH--- 2567

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             +T T+ VNI  ++   P+FS   Y  SV ED  V +  VI +++  + ++     IR+ 
Sbjct: 2568 HATTTVEVNIASESVKVPRFSNSHYLFSVMEDADVGN--VIGRVQQMETEI---DEIRFT 2622

Query: 191  IIGGNTQ----MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            I+ G+ +    + FS++  +G + +  +LD E+   +++ IRA   G       T + ++
Sbjct: 2623 IVPGSEESDSFLPFSVERSTGKIIVKSSLDRERKNQWKMTIRADAAGGVHA--ITTVTVD 2680

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            I DVNDNAP F+    + ++SE+  +G S+    A D D+  +  + +++ +++      
Sbjct: 2681 IGDVNDNAPAFHGDYERFTISEDAAVGTSVTIFSAMDRDDSPSGRIRFSLVEENPY---- 2736

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
                ++  SGW+  + QLDRE    Y+L+  ATD G    +                  F
Sbjct: 2737 --FDLNENSGWLTVASQLDREKIDHYKLIARATDEGG--FNTDLPFTIVVSDVNDSPPQF 2792

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLIT 424
               ++ ++L    P  +P++  +  D D   +N   + I  GN  G F I S N    + 
Sbjct: 2793 EKEEFNIDL--HLPSTSPILHFSIKDDDLSPNNVSQFFIPKGNEEGVFWIDSNND---LL 2847

Query: 425  VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
            + +P   + + +Y L V+A D G    +  V+IN+  + +       A  T  + E++  
Sbjct: 2848 LKRPEIVENKMQYQLKVTAFD-GVFETSTKVKINLKSSKDSDIRCPEANKTVILAENSKK 2906

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            GT VL  S+      +   +T+ LS    N  V +     V   ++  I   K    + +
Sbjct: 2907 GTVVLGESSL-----LGPNVTFKLSDNDGNVFVVNFRNGIVKVKESDQIDYEK---NQQL 2958

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS----V 600
              + LT+         L     + + + ++NDN P   ++L   +I E+          +
Sbjct: 2959 EFHRLTIQDNSEVCKEL-----ITVVIENLNDNRPKIIEKLLKVSIDENLPTSEDARQYI 3013

Query: 601  SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
            +++ A DAD      I + +   D   G F ID  +GV+   K LD E +   +L  VA 
Sbjct: 3014 TRIVAEDADF---DEIKFRM--VDDFGGLFQIDDINGVVTVVKPLDSEILGFFNLTVVAS 3068

Query: 661  DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
            DG    +++ ++  I   D ND+ P FE    +  + E+  IG  +   RA   D+  N 
Sbjct: 3069 DGEFEDKATILVTVI---DQNDNAPTFEKSTYSMKVMESESIGYELAHFRASGGDQ--NE 3123

Query: 721  VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRV 780
             + Y +K  D ++  +L  + G     L   +D +  S  K   +   +  PPL  + +V
Sbjct: 3124 TIEYYLKPSDVTSFVNLNAQTGI--LTLAKPLDFETLSALKLTVVAKDSGVPPLETEAQV 3181

Query: 781  EILVTDVNDNAP 792
            EI V D NDNAP
Sbjct: 3182 EISVMDENDNAP 3193



 Score =  190 bits (464), Expect = 4e-46
 Identities = 194/758 (25%), Positives = 317/758 (41%), Gaps = 75/758 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I+V D ND+ P   +Q   A + E    G  V  + A D+DIG+N+++++         L
Sbjct: 829  ISVEDVNDNPPKCVVQHSRARIPEDLPHGAFVSCMAAFDEDIGQNSKLKFL--------L 880

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS---LDREKVARYTVLVKATDQASPVS 127
            N E                FRID  SG +   A    LD  K   + + ++  D   P+ 
Sbjct: 881  NSEKVP-------------FRIDHHSGCIFIHAPEYPLDYHKTPFFNLSIEVADHGDPI- 926

Query: 128  DRLSSTATIHVNIIDDNDNYP--QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
              LS++  +HV ++D   N+   +F +     SV E+  +    ++ + K T  +    +
Sbjct: 927  --LSTSCHLHVELVDIAHNHLAIEFDDVAKEASVYENSEIGTEVIMIEAKETGDEQKVKA 984

Query: 186  A-IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS-----PSRSN 239
              + Y IIGG+    FSID   G V     LD E   +Y + + A+D  +     P R +
Sbjct: 985  ENLEYRIIGGDGWPHFSIDQ-KGTVRTTHLLDRETKSAYWITVEARDSKTDLYKDPRRRD 1043

Query: 240  TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
               + I I D ND+ P     ++  SV+EN P    IV+V+A DAD+ V+ +    +  K
Sbjct: 1044 VLHVFIRILDRNDHRPVAKKPMYIASVAENSPANVVIVKVEATDADD-VDNDAAAPLMFK 1102

Query: 300  DYTGNVDLPITIDPRSGWVYTSG--QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357
               G+      ID  SG++ TSG  +LDRE Q++++L V+  DGG+P   +         
Sbjct: 1103 IERGDPQSFFRIDLTSGYITTSGIRRLDREKQSEHELWVSICDGGEPQLCSNVIVIVNVL 1162

Query: 358  XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ 417
                    F    +   +          +     D  E+ RL Y IT G+ R  FSI + 
Sbjct: 1163 DENDNSPTFTQAIHHYSVRSKFAGKLCRIFAVDADEGENARLTYNITEGDAR--FSIDN- 1219

Query: 418  NGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAM-VQINITDANNYAPVFENAP- 473
            NG  + + A       +  Y LTV ATD G  G+   A  V +    A       +N+P 
Sbjct: 1220 NGNIIASEA----IHGDESYALTVQATDHGTPGQQFAATRVVLTANSAGQKPRKSKNSPP 1275

Query: 474  --------YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525
                    Y   + +   +G TV  + A+D+D     ++ +S+SS          D  F 
Sbjct: 1276 EISGKKSDYVIPISDADQVGLTVGKLEASDAD---GDELWWSISS-------GDPDSVFD 1325

Query: 526  INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585
            +   TG +   K ++        L ++  DG      D + V I V       P F    
Sbjct: 1326 VRQDTGQLLLAKKVELLKRGELRLNISVTDG---QAWDHSTVIIQVSRQISQRPKFSASH 1382

Query: 586  YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD-REEGSFVIDPASGVIRTNKA 644
            Y  ++ E   VGT +  + A+   +G    +       D   E    ++P+SG +   + 
Sbjct: 1383 YQTDVSERVAVGTQIYTLKASGESLGTKPLVFNLFSVDDVAMEDKIRVEPSSGNVIVMEP 1442

Query: 645  LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
            LD E  A   ++AV +        S     + I D ND+ P F       ++ E+  +  
Sbjct: 1443 LDYE--AARRIRAV-VQVQQANMKSFATFSVNINDENDNSPYFVGHTAFAFVDESDTVDD 1499

Query: 705  TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
             +  + A D D G N +V YSI  G++ + F ++ + G
Sbjct: 1500 VLATVTAFDKDRGENGIVTYSIVSGNEESLFKIDAKSG 1537



 Score =  188 bits (459), Expect = 1e-45
 Identities = 199/801 (24%), Positives = 349/801 (43%), Gaps = 79/801 (9%)

Query: 90   FRIDGRSGALLTRASLDR-EKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
            F I  ++G L   A ++R E+V  + V+         ++++L+    + + I+D ND+ P
Sbjct: 436  FAIGSKNGILRVSAKINRSERVYNFKVIASLHG----INEKLAEK-DVSIEILDSNDHAP 490

Query: 149  QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
             FS K    +    +      V+ K+ ATD D G N  I Y      +++   I++ +G+
Sbjct: 491  VFSAKWMRQT--PIVIGKPGDVLVKVDATDQDEGENGKIVYKF---TSELPLEINANTGE 545

Query: 209  VSLVKTLDYEQVRSYRLVIRAQDGGSP-SRSNTTQLL--------------INIRD-VND 252
            ++LV+    ++  S+   + A D G P SR +   L+              I I++  N 
Sbjct: 546  ITLVEV--PKKGNSWPATVWAIDLGLPLSRMSALNLMFYKNGTKIPAKPKPIIIQESENK 603

Query: 253  NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312
            ++P F +      V+E+ PIG  + ++QA D D G N  + Y +   D  G+    +T+D
Sbjct: 604  HSPVFSSFPEIVEVTEDAPIGTVVAKLQANDEDTGYNGFIRYVI--HDIAGSSHEVLTVD 661

Query: 313  PRSGWVYTSGQLDRETQAK--------------------YQLLVTATDGGDPPRSATATX 352
             +SG +  +  L +  + K                    +QL V+A D G P +S+  T 
Sbjct: 662  EQSGEITVASDLSKLMKEKLEVLDVQVHYIKHVTSNISNFQLKVSAIDAGTPVKSSVKTM 721

Query: 353  XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRF 412
                         F    Y + ++E+E PG  +  +TA D D  N    + + GN + + 
Sbjct: 722  KLRIKDVNNHSPQFDEVSYYLRISENEKPGKDIFKVTANDFDGGNNGKIKFSLGNNQEKS 781

Query: 413  SITSQNGR-GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVF 469
            S+ S + + G++ + + LD + +  +   + A+D G   R     + I++ D N+  P  
Sbjct: 782  SVISIDAKTGIVKLLKSLDREDQDVHTFAIIASDEGFPMRVSVTNLTISVEDVNDNPPKC 841

Query: 470  ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
                  A + ED P G  V  ++A D D+G N+++ + L+SE     + HH     I+  
Sbjct: 842  VVQHSRARIPEDLPHGAFVSCMAAFDEDIGQNSKLKFLLNSEKVPFRIDHHSGCIFIH-- 899

Query: 530  TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV--FKQQLYT 587
                     LD      + L++   D G P LS +  + + +VD+  N     F      
Sbjct: 900  ----APEYPLDYHKTPFFNLSIEVADHGDPILSTSCHLHVELVDIAHNHLAIEFDDVAKE 955

Query: 588  ANIMEDALVGTSVSQVGAT---DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA 644
            A++ E++ +GT V  + A    D        + Y +   D     F ID   G +RT   
Sbjct: 956  ASVYENSEIGTEVIMIEAKETGDEQKVKAENLEYRIIGGDGWP-HFSID-QKGTVRTTHL 1013

Query: 645  LDRESVATHDLKAVAIDGGT-----PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699
            LDRE+ + + +   A D  T     P +   + V I+I D ND  PV +       ++EN
Sbjct: 1014 LDRETKSAYWITVEARDSKTDLYKDPRRRDVLHVFIRILDRNDHRPVAKKPMYIASVAEN 1073

Query: 700  SPIGTTIGEIRAHDPDEGPN---AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756
            SP    I ++ A D D+  N   A + + I+ GD  + F ++   G      +  +D + 
Sbjct: 1074 SPANVVIVKVEATDADDVDNDAAAPLMFKIERGDPQSFFRIDLTSGYITTSGIRRLDREK 1133

Query: 757  ESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRV 816
            +S  + +  +     P L ++V V + V D NDN+P      I   + +  F  G   R+
Sbjct: 1134 QSEHELWVSICDGGEPQLCSNVIVIVNVLDENDNSPTFTQ-AIHHYSVRSKF-AGKLCRI 1191

Query: 817  PAYDADVTD--KLQYRILSGN 835
             A DAD  +  +L Y I  G+
Sbjct: 1192 FAVDADEGENARLTYNITEGD 1212



 Score =  184 bits (447), Expect = 4e-44
 Identities = 218/905 (24%), Positives = 379/905 (41%), Gaps = 90/905 (9%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATD-QDIGKNAEVEYTIELV 65
            +H  I +LD NDH PV +   Y ASV E + +   ++ ++ATD  D+  +A      ++ 
Sbjct: 1045 LHVFIRILDRNDHRPVAKKPMYIASVAENSPANVVIVKVEATDADDVDNDAAAPLMFKIE 1104

Query: 66   TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRA--SLDREKVARYTVLVKATDQA 123
              D                  Q  FRID  SG + T     LDREK + + + V   D  
Sbjct: 1105 RGDP-----------------QSFFRIDLTSGYITTSGIRRLDREKQSEHELWVSICDGG 1147

Query: 124  SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183
             P   +L S   + VN++D+NDN P F++  +  SV    +      + +I A DAD G 
Sbjct: 1148 EP---QLCSNVIVIVNVLDENDNSPTFTQAIHHYSVRSKFAGK----LCRIFAVDADEGE 1200

Query: 184  NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS-NTTQ 242
            N+ + Y I  G+ +  FSID+ +G++   + +  ++  SY L ++A D G+P +    T+
Sbjct: 1201 NARLTYNITEGDAR--FSIDN-NGNIIASEAIHGDE--SYALTVQATDHGTPGQQFAATR 1255

Query: 243  LLINIRDVND------NAPRFYT---SLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293
            +++             N+P   +   S +   +S+   +G ++ +++A DAD     EL 
Sbjct: 1256 VVLTANSAGQKPRKSKNSPPEISGKKSDYVIPISDADQVGLTVGKLEASDAD---GDELW 1312

Query: 294  YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353
            ++++    +G+ D    +   +G +  + +++   + + +L ++ TDG     S   T  
Sbjct: 1313 WSIS----SGDPDSVFDVRQDTGQLLLAKKVELLKRGELRLNISVTDGQAWDHS---TVI 1365

Query: 354  XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR-LHYEITG-GNTRGR 411
                        F    Y+ +++E    GT + TL A+      + L + +    +    
Sbjct: 1366 IQVSRQISQRPKFSASHYQTDVSERVAVGTQIYTLKASGESLGTKPLVFNLFSVDDVAME 1425

Query: 412  FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN 471
              I  +   G + V +PLD++  RR    V    +  +S  A   +NI D N+ +P F  
Sbjct: 1426 DKIRVEPSSGNVIVMEPLDYEAARRIRAVVQVQQANMKS-FATFSVNINDENDNSPYFVG 1484

Query: 472  APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
                A V E   +   +  V+A D D G N  +TYS+ S   NE     +  F I+ ++G
Sbjct: 1485 HTAFAFVDESDTVDDVLATVTAFDKDRGENGIVTYSIVS--GNE-----ESLFKIDAKSG 1537

Query: 532  AITTNKLLDRETMS-GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590
             +   K LD E      +L + A D    SL D   + I   +       F +++Y   +
Sbjct: 1538 EVRLAKPLDPELQHVESILRIRAIDSAANSLKDEMSLHIRNSNEAPETAKFDRKVYQTTL 1597

Query: 591  MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650
             +    GT V  + A       +G + Y+L+P       F +   SG +     L +   
Sbjct: 1598 YDSTRPGTPVLVLNALH-----HGTVSYKLEPNCT---FFEVHTLSGAVHLATWLTKLK- 1648

Query: 651  ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE-- 708
                ++  AI   T  Q     V  KI   N   P+F        I EN P G+++    
Sbjct: 1649 HRKSVECTAIVESTEGQQDIAKVIAKIIRTNQHSPIFRRQVYRGTIRENMPTGSSVLSKS 1708

Query: 709  -----IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY 763
                 + A D D G N +V Y +    D   FS++   G+    + T +  D+E   K+Y
Sbjct: 1709 LLPLVVSAIDEDPGSNGLVGYRMLSPKDEQMFSVDQYSGA----IRTQMSFDFEK-MKEY 1763

Query: 764  ELVIRA---ASPPLWNDVRVEILVT--DVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA 818
               ++A     PP  + +   I+VT  D ND  P      +  +           G   A
Sbjct: 1764 SFYVQAFDMGQPPRRSLMPSLIVVTVIDENDEPPRFPSNSLDISMILPTANGVSVGGQTA 1823

Query: 819  YDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKA 878
             D D    L+Y  +   +    + ++T   +       +++ KL  +EV VTDG      
Sbjct: 1824 QDMDSVGSLRY-FIKDQSVPFSVDSKTGDVLVKDSNGISDMTKLFDLEVFVTDGKQSASY 1882

Query: 879  MMQLS 883
            +M++S
Sbjct: 1883 VMKIS 1887



 Score =  182 bits (442), Expect = 2e-43
 Identities = 193/812 (23%), Positives = 351/812 (43%), Gaps = 73/812 (8%)

Query: 106  DREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSV-----D 160
            D     ++  ++ ATD  +  S    S   ++  I+D ++     S  T  +S+      
Sbjct: 2311 DSAITGQFITIMSATDMDTTNSLDEESQKLLY-KIVDGDETLFNISPATGELSLARPVEQ 2369

Query: 161  EDISVTDNPVIAKIKATDADVGANSAI-RYAIIGGNTQMQFS------------------ 201
            +D+   D   +  +  TD  +   SA+   A+ GG   +QFS                  
Sbjct: 2370 DDLVNEDTKKVLNVSVTDGIIVNKSALLTVAVKGGVPPLQFSLAPTTSSNSSTSKEAWPV 2429

Query: 202  -IDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260
             ID  +G + + + L+Y + + Y++ +  +D  +  R   + L +++ D+ND  P F   
Sbjct: 2430 AIDRKTGRIHVSRVLNYHRDKRYQIPLVVED--ATGRRAFSTLTLSVIDINDKPPFFVLP 2487

Query: 261  LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT 320
             +  S+SE+   G +++ V A D DE  N  + Y++ D    G+     ++ PR G +  
Sbjct: 2488 FYSTSISESAKEGDTVMMVSATDDDE--NDTIEYSLLD----GSESQFFSVHPRQGTITV 2541

Query: 321  SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380
            + +L+ +      L + ATD  +PP  AT T              F    Y   + ED  
Sbjct: 2542 AKKLEHKAGVTLSLTIKATDSANPPHHATTTVEVNIASESVKVPRFSNSHYLFSVMEDAD 2601

Query: 381  PGTPVVTLTATDADEDNRLHYEITGGNTRGRF-SITSQNGRGLITVAQPLDFKQERRYVL 439
             G  +  +   + + D      + G      F   + +   G I V   LD +++ ++ +
Sbjct: 2602 VGNVIGRVQQMETEIDEIRFTIVPGSEESDSFLPFSVERSTGKIIVKSSLDRERKNQWKM 2661

Query: 440  TVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499
            T+ A  +GG      V ++I D N+ AP F       ++ EDA +GT+V + SA D D  
Sbjct: 2662 TIRADAAGGVHAITTVTVDIGDVNDNAPAFHGDYERFTISEDAAVGTSVTIFSAMDRDDS 2721

Query: 500  INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
             + +I +SL  E         +  F +N  +G +T    LDRE +  Y L   A D G  
Sbjct: 2722 PSGRIRFSLVEE---------NPYFDLNENSGWLTVASQLDREKIDHYKLIARATDEG-- 2770

Query: 560  SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS-VSQVGATDADVGLNGRIHY 618
              +      I V DVND+ P F+++ +  ++    L  TS +      D D+  N    +
Sbjct: 2771 GFNTDLPFTIVVSDVNDSPPQFEKEEFNIDL---HLPSTSPILHFSIKDDDLSPNNVSQF 2827

Query: 619  ELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678
             + PK  EEG F ID  + ++     +  E+   + LK  A DG    ++ST  V I ++
Sbjct: 2828 FI-PKGNEEGVFWIDSNNDLLLKRPEI-VENKMQYQLKVTAFDGVF--ETSTK-VKINLK 2882

Query: 679  DINDSPPVFESDCLTFYISENSPIGTTI-GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL 737
               DS         T  ++ENS  GT + GE        GPN     S    +D N F +
Sbjct: 2883 SSKDSDIRCPEANKTVILAENSKKGTVVLGESSL----LGPNVTFKLS---DNDGNVFVV 2935

Query: 738  ETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDF 797
              R G  K +    +D +     + + L I+  S  +  ++ + +++ ++NDN P + + 
Sbjct: 2936 NFRNGIVKVKESDQIDYEKNQQLEFHRLTIQDNS-EVCKEL-ITVVIENLNDNRPKIIE- 2992

Query: 798  QIIFNNYKDCFPVGP-----FGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLS 852
            +++  +  +  P          R+ A DAD  D++++R++  +   L  +++  G +T+ 
Sbjct: 2993 KLLKVSIDENLPTSEDARQYITRIVAEDADF-DEIKFRMVD-DFGGLFQIDDINGVVTVV 3050

Query: 853  PQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884
              L++ +     + V  +DG  E KA + ++V
Sbjct: 3051 KPLDSEILGFFNLTVVASDGEFEDKATILVTV 3082



 Score =  175 bits (427), Expect = 1e-41
 Identities = 220/912 (24%), Positives = 391/912 (42%), Gaps = 92/912 (10%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ + D N+HSP F+   Y   + E    G  +  + A D D G N ++++++       
Sbjct: 722  KLRIKDVNNHSPQFDEVSYYLRISENEKPGKDIFKVTANDFDGGNNGKIKFSLG------ 775

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             N ++              V  ID ++G +    SLDRE    +T  + A+D+  P+  R
Sbjct: 776  -NNQEK-----------SSVISIDAKTGIVKLLKSLDREDQDVHTFAIIASDEGFPM--R 821

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            +S T  + +++ D NDN P+   +     + ED+       ++ + A D D+G NS +++
Sbjct: 822  VSVT-NLTISVEDVNDNPPKCVVQHSRARIPEDL--PHGAFVSCMAAFDEDIGQNSKLKF 878

Query: 190  AIIGGNTQMQFSIDSLSGDVSL---VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
             +   + ++ F ID  SG + +      LDY +   + L I   D G P  S +  L + 
Sbjct: 879  LL--NSEKVPFRIDHHSGCIFIHAPEYPLDYHKTPFFNLSIEVADHGDPILSTSCHLHVE 936

Query: 247  IRDVNDN--APRFYTSLFQESVSENVPIGYSIVRVQAYDA--DEGVNAE-LTYTMTDKDY 301
            + D+  N  A  F     + SV EN  IG  ++ ++A +   ++ V AE L Y +   D 
Sbjct: 937  LVDIAHNHLAIEFDDVAKEASVYENSEIGTEVIMIEAKETGDEQKVKAENLEYRIIGGDG 996

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG-----GDPPRSATATXXXXX 356
              +     +ID + G V T+  LDRET++ Y + V A D       DP R          
Sbjct: 997  WPH----FSID-QKGTVRTTHLLDRETKSAYWITVEARDSKTDLYKDPRRRDVLHVFIRI 1051

Query: 357  XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DN----RLHYEITGGNTRGR 411
                          Y   +AE+ P    +V + ATDAD+ DN     L ++I  G+ +  
Sbjct: 1052 LDRNDHRPVAKKPMYIASVAENSPANVVIVKVEATDADDVDNDAAAPLMFKIERGDPQSF 1111

Query: 412  FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVF 469
            F I   +G    +  + LD +++  + L VS  D G        +V +N+ D N+ +P F
Sbjct: 1112 FRIDLTSGYITTSGIRRLDREKQSEHELWVSICDGGEPQLCSNVIVIVNVLDENDNSPTF 1171

Query: 470  ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
              A +  SV   +     +  + A D+D G NA++TY+         +   D +F I+  
Sbjct: 1172 TQAIHHYSV--RSKFAGKLCRIFAVDADEGENARLTYN---------ITEGDARFSIDNN 1220

Query: 530  TGAITTNKLLDRETMSGYLLTVTARDGGVPSLS-DTTDVEISVVDV------NDNEP--- 579
               I +  +   E+   Y LTV A D G P      T V ++          + N P   
Sbjct: 1221 GNIIASEAIHGDES---YALTVQATDHGTPGQQFAATRVVLTANSAGQKPRKSKNSPPEI 1277

Query: 580  VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639
              K+  Y   I +   VG +V ++ A+DAD      + + +   D  +  F +   +G +
Sbjct: 1278 SGKKSDYVIPISDADQVGLTVGKLEASDAD---GDELWWSISSGD-PDSVFDVRQDTGQL 1333

Query: 640  RTNKALDRESVATHDLKA-VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698
               K +  E +   +L+  +++  G     STVI+ +    I+  P  F +      +SE
Sbjct: 1334 LLAKKV--ELLKRGELRLNISVTDGQAWDHSTVIIQVS-RQISQRPK-FSASHYQTDVSE 1389

Query: 699  NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758
               +GT I  ++A     G   +V +++   DD  +   + R       ++ M  LDYE+
Sbjct: 1390 RVAVGTQIYTLKASGESLGTKPLV-FNLFSVDDV-AMEDKIRVEPSSGNVIVMEPLDYEA 1447

Query: 759  PRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP-VMKDFQIIFNNYKDCFPVGPFGRVP 817
             R +   V++     + +     + + D NDN+P  +      F +  D         V 
Sbjct: 1448 AR-RIRAVVQVQQANMKSFATFSVNINDENDNSPYFVGHTAFAFVDESDTVD-DVLATVT 1505

Query: 818  AYDADVTDK--LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKL-ATMEVSVTD-GV 873
            A+D D  +   + Y I+SGN  +L  ++  +G + L+  L+  +  + + + +   D   
Sbjct: 1506 AFDKDRGENGIVTYSIVSGNEESLFKIDAKSGEVRLAKPLDPELQHVESILRIRAIDSAA 1565

Query: 874  NEIKAMMQLSVR 885
            N +K  M L +R
Sbjct: 1566 NSLKDEMSLHIR 1577



 Score =  159 bits (386), Expect = 1e-36
 Identities = 188/809 (23%), Positives = 335/809 (41%), Gaps = 62/809 (7%)

Query: 92   IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151
            ID ++G +     L+  +  RY + +   D       R  ST T+  ++ID ND  P F 
Sbjct: 2431 IDRKTGRIHVSRVLNYHRDKRYQIPLVVEDATGR---RAFSTLTL--SVIDINDKPPFFV 2485

Query: 152  EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSL 211
               Y+ S+ E  S  +   +  + ATD D   N  I Y+++ G+    FS+    G +++
Sbjct: 2486 LPFYSTSISE--SAKEGDTVMMVSATDDD--ENDTIEYSLLDGSESQFFSVHPRQGTITV 2541

Query: 212  VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271
             K L+++   +  L I+A D  +P    TT + +NI   +   PRF  S +  SV E+  
Sbjct: 2542 AKKLEHKAGVTLSLTIKATDSANPPHHATTTVEVNIASESVKVPRFSNSHYLFSVMEDAD 2601

Query: 272  IGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK 331
            +G  I RVQ  + +     E+ +T+       +  LP +++  +G +     LDRE + +
Sbjct: 2602 VGNVIGRVQQMETEID---EIRFTIVPGSEESDSFLPFSVERSTGKIIVKSSLDRERKNQ 2658

Query: 332  YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE-VELAEDEPPGTPVVTLTA 390
            +++ + A   G      T T                 G YE   ++ED   GT V   +A
Sbjct: 2659 WKMTIRADAAGGVHAITTVTVDIGDVNDNAPA---FHGDYERFTISEDAAVGTSVTIFSA 2715

Query: 391  TDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG 448
             D D+    R+ + +   N    F +   +  G +TVA  LD ++   Y L   ATD GG
Sbjct: 2716 MDRDDSPSGRIRFSLVEENP--YFDLNENS--GWLTVASQLDREKIDHYKLIARATDEGG 2771

Query: 449  RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508
             +      I ++D N+  P FE   +   +    P  + +L  S  D D+  N  ++   
Sbjct: 2772 FNTDLPFTIVVSDVNDSPPQFEKEEFNIDL--HLPSTSPILHFSIKDDDLSPN-NVSQFF 2828

Query: 509  SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568
              + + E V   D    +  +   I  NK+        Y L VTA DG       +T V+
Sbjct: 2829 IPKGNEEGVFWIDSNNDLLLKRPEIVENKM-------QYQLKVTAFDG---VFETSTKVK 2878

Query: 569  ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG 628
            I++    D++    +   T  + E++  GT V  +G +     L   + ++L   D +  
Sbjct: 2879 INLKSSKDSDIRCPEANKTVILAENSKKGTVV--LGESSL---LGPNVTFKL--SDNDGN 2931

Query: 629  SFVIDPASGVIRTNKA--LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686
             FV++  +G+++  ++  +D E     +   + I   +  +    ++ + IE++ND+ P 
Sbjct: 2932 VFVVNFRNGIVKVKESDQIDYEKNQQLEFHRLTIQDNS--EVCKELITVVIENLNDNRPK 2989

Query: 687  FESDCLTFYISENSPIGTT----IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
                 L   I EN P        I  I A D D      + + +   D    F ++   G
Sbjct: 2990 IIEKLLKVSIDENLPTSEDARQYITRIVAEDADFDE---IKFRMV-DDFGGLFQIDDING 3045

Query: 743  SDKAELVTMV-DLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801
                 +VT+V  LD E     + L + A+     +   + + V D NDNAP  +      
Sbjct: 3046 -----VVTVVKPLDSEI-LGFFNLTVVASDGEFEDKATILVTVIDQNDNAPTFEKSTYSM 3099

Query: 802  NNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPK 861
               +            A   D  + ++Y +   +  + + LN  TG +TL+  L+     
Sbjct: 3100 KVMESESIGYELAHFRASGGDQNETIEYYLKPSDVTSFVNLNAQTGILTLAKPLDFETLS 3159

Query: 862  LATMEVSVTD-GVNEIKAMMQLSVRLITE 889
               + V   D GV  ++   Q+ + ++ E
Sbjct: 3160 ALKLTVVAKDSGVPPLETEAQVEISVMDE 3188



 Score =  152 bits (368), Expect = 2e-34
 Identities = 203/770 (26%), Positives = 326/770 (42%), Gaps = 86/770 (11%)

Query: 13   VLDCNDHSPVFEMQQYEASVREGASSGTTVLT-------LKATDQDIGKNAEVEYTIELV 65
            ++  N HSP+F  Q Y  ++RE   +G++VL+       + A D+D G N  V Y +   
Sbjct: 1675 IIRTNQHSPIFRRQVYRGTIRENMPTGSSVLSKSLLPLVVSAIDEDPGSNGLVGYRM--- 1731

Query: 66   TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125
                L+P+D            + +F +D  SGA+ T+ S D EK+  Y+  V+A D   P
Sbjct: 1732 ----LSPKD------------EQMFSVDQYSGAIRTQMSFDFEKMKEYSFYVQAFDMGQP 1775

Query: 126  VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
                L  +  + V +ID+ND  P+F   +  +S+   I  T N V      T  D+ +  
Sbjct: 1776 PRRSLMPSLIV-VTVIDENDEPPRFPSNSLDISM---ILPTANGVSVG-GQTAQDMDSVG 1830

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLD--YEQVRSYRLVIRAQDGGSPSRSNTTQL 243
            ++RY I   +  + FS+DS +GDV LVK  +   +  + + L +   DG    +S +  +
Sbjct: 1831 SLRYFI--KDQSVPFSVDSKTGDV-LVKDSNGISDMTKLFDLEVFVTDG---KQSASYVM 1884

Query: 244  LINIRDVNDNAPRFYTSLFQESVSEN--VPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
             I+     ++  +F  + +  S+ EN  +P G SI+   A   D+           D   
Sbjct: 1885 KISTISTENSKFKFTRNEYHTSLIENTTLPPG-SIILSVATIGDK----------LDHFS 1933

Query: 302  TGNVDLPITIDPRSGWVYTSG-QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
              N      I P +G + +SG  LDRE  A  +L+V A      P  A A          
Sbjct: 1934 IVNPHEAFFIHPGTGVISSSGIALDREKSAIIRLVVQAKSHEKNPVMARALVVVGIENIN 1993

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420
                 FM   Y++ +   +  GT V+     D DE + +   I+  N    F I    G+
Sbjct: 1994 DETPIFMGTPYDITIGHSD-IGTVVLEPKVIDNDEGDVV--TISSENMPEYFKIV--GGK 2048

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSGG-RSDTAMVQINITDANNYAPVFENAPYTASVF 479
             ++    P   +++  +   + A D+G        V+I + D     PVF    YTA + 
Sbjct: 2049 VVLGKKLPSIEEEDLEFNFKLIAKDNGSVHRVEEPVKIRVVD--KARPVFSQNVYTAVIS 2106

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
            +++   +TVLV     S +        S S  +    +      F ++  TG +  N  L
Sbjct: 2107 KESTKKSTVLVKVMAKSSL-------QSKSKGLIGYRILDKKSPFSVDFLTGEVRLNN-L 2158

Query: 540  DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD-VNDNEPVFKQQLYTANIMEDALVGT 598
                 + Y   V AR+   P +     VEI V   +  + PVF++  YTA+  E   +G 
Sbjct: 2159 KMLAETNYTFEVEAREVTRPKMIAKAQVEIIVKSGITTHAPVFEKLKYTASTPESTSIGQ 2218

Query: 599  SVSQVGATDADVGLNGRIHYELD-PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
             +  + AT +D   N  I Y L   KD E     I P +G +     LD E    +DLK 
Sbjct: 2219 RLLTIKATTSDE--NDTIEYSLSGSKDIE-----IHPETGDVTITGQLDYEKTQKYDLKL 2271

Query: 658  VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-- 715
            VA   G    S    + + IED+ND  P F    ++  IS+++  G  I  + A D D  
Sbjct: 2272 VATSSGKQVSSEAEFI-VLIEDVNDEMPEFIRSDVSAKISDSAITGQFITIMSATDMDTT 2330

Query: 716  ---EGPNAVVHYSIKGGDDSNSFSLETRQGS-DKAELVTMVDLDYESPRK 761
               +  +  + Y I  GD++  F++    G    A  V   DL  E  +K
Sbjct: 2331 NSLDEESQKLLYKIVDGDET-LFNISPATGELSLARPVEQDDLVNEDTKK 2379



 Score =  143 bits (347), Expect = 5e-32
 Identities = 191/785 (24%), Positives = 333/785 (42%), Gaps = 84/785 (10%)

Query: 134  ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK------IKATDADVGANSAI 187
            A +   II  N + P F  + Y  ++ E++  T + V++K      + A D D G+N  +
Sbjct: 1669 AKVIAKIIRTNQHSPIFRRQVYRGTIRENMP-TGSSVLSKSLLPLVVSAIDEDPGSNGLV 1727

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN--TTQLLI 245
             Y ++    +  FS+D  SG +    + D+E+++ Y   ++A D G P R +   + +++
Sbjct: 1728 GYRMLSPKDEQMFSVDQYSGAIRTQMSFDFEKMKEYSFYVQAFDMGQPPRRSLMPSLIVV 1787

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
             + D ND  PRF ++    S+      G S+    A D D      L Y + D+      
Sbjct: 1788 TVIDENDEPPRFPSNSLDISMILPTANGVSVGGQTAQDMDS--VGSLRYFIKDQ------ 1839

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
             +P ++D ++G V            K + L V  TDG    +SA+               
Sbjct: 1840 SVPFSVDSKTGDVLVKDSNGISDMTKLFDLEVFVTDG---KQSASYVMKISTISTENSKF 1896

Query: 365  XFMPGQYEVELAEDE--PPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422
             F   +Y   L E+   PPG+ ++   AT  D+ +  H+ I   N    F I    G G+
Sbjct: 1897 KFTRNEYHTSLIENTTLPPGS-IILSVATIGDKLD--HFSIV--NPHEAFFI--HPGTGV 1949

Query: 423  ITVAQ-PLDFKQER--RYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479
            I+ +   LD ++    R V+   + +       A+V + I + N+  P+F   PY  ++ 
Sbjct: 1950 ISSSGIALDREKSAIIRLVVQAKSHEKNPVMARALVVVGIENINDETPIFMGTPYDITI- 2008

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
              + IGT VL     D+D G       ++SSE   E       + V+  +  +I      
Sbjct: 2009 GHSDIGTVVLEPKVIDNDEG----DVVTISSENMPEYFKIVGGKVVLGKKLPSI------ 2058

Query: 540  DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
            + E +      +   +G V  + +   V+I VVD     PVF Q +YTA I +++   ++
Sbjct: 2059 EEEDLEFNFKLIAKDNGSVHRVEE--PVKIRVVD--KARPVFSQNVYTAVISKESTKKST 2114

Query: 600  --VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
              V  +  +       G I Y +  K   +  F +D  +G +R N  L   +   +  + 
Sbjct: 2115 VLVKVMAKSSLQSKSKGLIGYRILDK---KSPFSVDFLTGEVRLNN-LKMLAETNYTFEV 2170

Query: 658  VAIDGGTPPQSSTVIVHIKIED-INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
             A +   P   +   V I ++  I    PVFE    T    E++ IG  +  I+A   DE
Sbjct: 2171 EAREVTRPKMIAKAQVEIIVKSGITTHAPVFEKLKYTASTPESTSIGQRLLTIKATTSDE 2230

Query: 717  GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIRAASPPLW 775
              N  + YS+ G  D     +E     +  ++     LDYE  +K   +LV  ++   + 
Sbjct: 2231 --NDTIEYSLSGSKD-----IEIH--PETGDVTITGQLDYEKTQKYDLKLVATSSGKQVS 2281

Query: 776  NDVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFPVGPFGRV-PAYDADVTD------- 825
            ++    +L+ DVND  P  +  D   +     D    G F  +  A D D T+       
Sbjct: 2282 SEAEFIVLIEDVNDEMPEFIRSD---VSAKISDSAITGQFITIMSATDMDTTNSLDEESQ 2338

Query: 826  KLQYRILSGNNANLILLNETTGSMTLSPQLN----TNVPKLATMEVSVTDGVNEIK-AMM 880
            KL Y+I+ G+   L  ++  TG ++L+  +      N      + VSVTDG+   K A++
Sbjct: 2339 KLLYKIVDGDE-TLFNISPATGELSLARPVEQDDLVNEDTKKVLNVSVTDGIIVNKSALL 2397

Query: 881  QLSVR 885
             ++V+
Sbjct: 2398 TVAVK 2402



 Score =  111 bits (266), Expect = 4e-22
 Identities = 133/533 (24%), Positives = 224/533 (42%), Gaps = 51/533 (9%)

Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVF 469
           F+I S+NG  ++ V+  ++ + ER Y   V A+  G     A   V I I D+N++APVF
Sbjct: 436 FAIGSKNG--ILRVSAKIN-RSERVYNFKVIASLHGINEKLAEKDVSIEILDSNDHAPVF 492

Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN-P 528
                  +       G  ++ V ATD D G N +I Y  +SE+  E  A+  +  ++  P
Sbjct: 493 SAKWMRQTPIVIGKPGDVLVKVDATDQDEGENGKIVYKFTSELPLEINANTGEITLVEVP 552

Query: 529 QTG--------AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580
           + G        AI     L R  MS   L        +P+      ++ S    N + PV
Sbjct: 553 KKGNSWPATVWAIDLGLPLSR--MSALNLMFYKNGTKIPAKPKPIIIQESE---NKHSPV 607

Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFVIDPASGVI 639
           F        + EDA +GT V+++ A D D G NG I Y + D          +D  SG I
Sbjct: 608 FSSFPEIVEVTEDAPIGTVVAKLQANDEDTGYNGFIRYVIHDIAGSSHEVLTVDEQSGEI 667

Query: 640 RTNKALDR--------------------ESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679
                L +                     +++   LK  AID GTP +SS   + ++I+D
Sbjct: 668 TVASDLSKLMKEKLEVLDVQVHYIKHVTSNISNFQLKVSAIDAGTPVKSSVKTMKLRIKD 727

Query: 680 INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS-FSLE 738
           +N+  P F+       ISEN   G  I ++ A+D D G N  + +S+    + +S  S++
Sbjct: 728 VNNHSPQFDEVSYYLRISENEKPGKDIFKVTANDFDGGNNGKIKFSLGNNQEKSSVISID 787

Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQ 798
            + G  K  L+  +D + +       +      P   +   + I V DVNDN P     Q
Sbjct: 788 AKTGIVK--LLKSLDREDQDVHTFAIIASDEGFPMRVSVTNLTISVEDVNDNPPKCV-VQ 844

Query: 799 IIFNNYKDCFPVGPF-GRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTL-SPQ-- 854
                  +  P G F   + A+D D+    + + L  +      ++  +G + + +P+  
Sbjct: 845 HSRARIPEDLPHGAFVSCMAAFDEDIGQNSKLKFLLNSEKVPFRIDHHSGCIFIHAPEYP 904

Query: 855 LNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAE 906
           L+ +      + + V D G   +     L V L+  ++  N + +  +D+  E
Sbjct: 905 LDYHKTPFFNLSIEVADHGDPILSTSCHLHVELV--DIAHNHLAIEFDDVAKE 955



 Score = 93.1 bits (221), Expect = 1e-16
 Identities = 80/278 (28%), Positives = 130/278 (46%), Gaps = 24/278 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I+V+D ND++P FE ++Y   V+E + SG  VLT+KA D D      V Y +E+V+  T
Sbjct: 3182 EISVMDENDNAPKFEKEKYVGKVKENSKSGEKVLTVKALDVDSEHFGAVSYELEIVSETT 3241

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             +                  F I+  +G +L   S+D EK+ +Y + V A D   P    
Sbjct: 3242 TDTPVL-------------PFAINS-NGDVLISQSIDYEKIKKYNLKVIAKDGGRP---P 3284

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            L S A + +++ D+ND+ P F +   T  V E  ++     + K   +D D   N A   
Sbjct: 3285 LRSEALLEIHVEDENDHAPTFDDCNMTALVQEGEAIGHR--LLKFSVSDLDGPKNGAPFT 3342

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
              I G+    F ++    ++   K L+Y +   Y L + A+D     ++    L I IR 
Sbjct: 3343 VEIQGDGAKSFKVNE-KLELLTAKKLEYRKKDKYLLTVIAKD--VKGKTTDCPLTIFIRQ 3399

Query: 250  VNDNAPRFYTSLFQESVSEN-VPIGYSIVRVQAYDADE 286
             + +AP       Q +  +N +P G  I R++A D DE
Sbjct: 3400 TSRHAPTMKPMKIQINTLQNELPEGI-IGRLKASDEDE 3436



 Score = 86.6 bits (205), Expect = 9e-15
 Identities = 148/696 (21%), Positives = 280/696 (40%), Gaps = 80/696 (11%)

Query: 240 TTQLLINIRDVNDNAPRFYTSL--FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297
           T ++ + + D ND +P F      ++  + +++    +++RV+A DAD G+N+ + +++ 
Sbjct: 136 TARIHLRVIDRNDASPVFLVGEQGYEAEIDDDLEPFSTVLRVEASDADIGINSAIYFSLV 195

Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTAT---------DGGDPPRSA 348
           ++ +         ++P +GWV +   L      KY L V +          D  +   S 
Sbjct: 196 NRSHD------FIVEPVTGWVRS---LRHVKPGKYSLKVKSEDRASRLYYFDENEVQPSW 246

Query: 349 TATXXXXXXXXXXXXXXFMPGQYEV--------ELAE----DEPPGTPVVTLTATDADED 396
           TA                +  Q ++        +LA      + P   +V L   + +  
Sbjct: 247 TADVLITVRETKPKPRRILVDQRKINPNILNNRQLAAIITLKDSPNDAIVGLKGNEKEHW 306

Query: 397 NRLHYEITG--GNTRGRFSITSQNGRGL---ITVAQPLDFKQERRYVLTVSATDSGGRSD 451
             +  E+ G  G    R+ + ++NG  +     V   +     RR   ++S       ++
Sbjct: 307 FEVEPEVVGNDGTKELRWMLYAKNGSQVPKNTNVTLTIGEDYIRRSGFSISKKPVIPTNE 366

Query: 452 TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE 511
           T  +QI    A +     +N   T    E APIG  +  ++    +    + I YSL  E
Sbjct: 367 TVTIQIERL-AEHLIRFLDNEKLTLKTDEMAPIGRILYRMNVNVENPDDVSLIRYSL--E 423

Query: 512 ISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571
            S   + +    F I  + G +  +  ++R     Y   V A   G+       DV I +
Sbjct: 424 YSKSDLPNATLPFAIGSKNGILRVSAKINRSERV-YNFKVIASLHGINEKLAEKDVSIEI 482

Query: 572 VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK-------D 624
           +D ND+ PVF  +      +     G  + +V ATD D G NG+I Y+   +       +
Sbjct: 483 LDSNDHAPVFSAKWMRQTPIVIGKPGDVLVKVDATDQDEGENGKIVYKFTSELPLEINAN 542

Query: 625 REEGSFVIDPASG------VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678
             E + V  P  G      V   +  L    ++  +L         P +   +I+    E
Sbjct: 543 TGEITLVEVPKKGNSWPATVWAIDLGLPLSRMSALNLMFYKNGTKIPAKPKPIIIQ---E 599

Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK--GGDDSNSFS 736
             N   PVF S      ++E++PIGT + +++A+D D G N  + Y I    G      +
Sbjct: 600 SENKHSPVFSSFPEIVEVTEDAPIGTVVAKLQANDEDTGYNGFIRYVIHDIAGSSHEVLT 659

Query: 737 LETRQG-----SDKAEL------VTMVDLDY----ESPRKKYELVIRA--ASPPLWNDVR 779
           ++ + G     SD ++L      V  V + Y     S    ++L + A  A  P+ + V+
Sbjct: 660 VDEQSGEITVASDLSKLMKEKLEVLDVQVHYIKHVTSNISNFQLKVSAIDAGTPVKSSVK 719

Query: 780 -VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNN-- 836
            +++ + DVN+++P   +        ++  P     +V A D D  +  + +   GNN  
Sbjct: 720 TMKLRIKDVNNHSPQFDEVSYYLRISENEKPGKDIFKVTANDFDGGNNGKIKFSLGNNQE 779

Query: 837 -ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            +++I ++  TG + L   L+     + T  +  +D
Sbjct: 780 KSSVISIDAKTGIVKLLKSLDREDQDVHTFAIIASD 815



 Score = 67.3 bits (157), Expect = 6e-09
 Identities = 42/132 (31%), Positives = 76/132 (57%), Gaps = 10/132 (7%)

Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQF--SEKTYTVSVDED 162
           L+RE    Y +LVKA  +   +S+ L +TA IH+ +ID ND  P F   E+ Y   +D+D
Sbjct: 109 LNRELKDFYDILVKAMCKRRDLSN-LETTARIHLRVIDRNDASPVFLVGEQGYEAEIDDD 167

Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222
           +       + +++A+DAD+G NSAI ++++  N    F ++ ++G    V++L + +   
Sbjct: 168 LEPFST--VLRVEASDADIGINSAIYFSLV--NRSHDFIVEPVTG---WVRSLRHVKPGK 220

Query: 223 YRLVIRAQDGGS 234
           Y L ++++D  S
Sbjct: 221 YSLKVKSEDRAS 232



 Score = 54.8 bits (126), Expect = 3e-05
 Identities = 34/107 (31%), Positives = 60/107 (56%), Gaps = 7/107 (6%)

Query: 539 LDRETMSGYLLTVTA--RDGGVPSLSDTTDVEISVVDVNDNEPVFK--QQLYTANIMEDA 594
           L+RE    Y + V A  +   + +L  T  + + V+D ND  PVF   +Q Y A I +D 
Sbjct: 109 LNRELKDFYDILVKAMCKRRDLSNLETTARIHLRVIDRNDASPVFLVGEQGYEAEIDDDL 168

Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641
              ++V +V A+DAD+G+N  I++ L  +  +   F+++P +G +R+
Sbjct: 169 EPFSTVLRVEASDADIGINSAIYFSLVNRSHD---FIVEPVTGWVRS 212



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 68/303 (22%), Positives = 111/303 (36%), Gaps = 38/303 (12%)

Query: 1310 CPEKRSRCSSAPCYNGAEC--SDLWDTYICDCKEGHTGKDCA----DSTGP-----PWRF 1358
            C  + ++C+ +PC     C  S    TY C C  G  G  C+     + G          
Sbjct: 3682 CEVETNQCAKSPCEQWQLCIPSVHNSTYECVCPLGMEGDKCSVPSCQNDGKCLEEAELSV 3741

Query: 1359 GGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVM---------SIQLKSGLLHYSYNGE 1409
            GGDG    + L   I+      + ++T   +  +M          ++L +G   Y +N  
Sbjct: 3742 GGDGYFEIS-LSNEIETRMELEIELKTTTHNGIIMWSRGKRDFHMLRLVNGTPEYHWNAG 3800

Query: 1410 T---MYLPMATLSDGAWHRIEIKWLGTDISVTV-DYGLRTVLMPMLANKIQGQYIGKILI 1465
            T   +     ++ DG WHRI I        +TV D  L+    P+ +  I      + L+
Sbjct: 3801 TGTGIVTSKTSVVDGQWHRIAISRRQRRTRMTVDDEDLQEAFSPIGSTVINLHRYSQKLV 3860

Query: 1466 GGLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRPTVR-ENVRDGCQ--SRADCMLSIC 1522
             G     G L   V     C + + +   + L  R  ++    + GC   + + C    C
Sbjct: 3861 LGAKVDDGELTDGV---SACFRTISVDGMKVLKTRQGMKLFGAQPGCSALTSSPCNDLPC 3917

Query: 1523 PPYSKCVTSWDSS-TCTCEAGRVGPQC---VSACELGPCGAA-RCVPDQTPKGYSCACEP 1577
                 C++   S   C C +   G  C   +  C   PC    +C+P      Y C C  
Sbjct: 3918 QHAGTCISQGKSHFKCECPSRYSGNVCEIDLEPCASSPCPTGIQCIPFY--NDYLCKCPN 3975

Query: 1578 GYT 1580
            G+T
Sbjct: 3976 GFT 3978



 Score = 48.4 bits (110), Expect = 0.003
 Identities = 86/377 (22%), Positives = 161/377 (42%), Gaps = 42/377 (11%)

Query: 445 DSGGRSDTAMVQINITDANNYAPVF--ENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502
           D      TA + + + D N+ +PVF      Y A + +D    +TVL V A+D+D+GIN+
Sbjct: 129 DLSNLETTARIHLRVIDRNDASPVFLVGEQGYEAEIDDDLEPFSTVLRVEASDADIGINS 188

Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD-GGVPSL 561
            I +SL +         HD  F++ P TG +   + L       Y L V + D       
Sbjct: 189 AIYFSLVNR-------SHD--FIVEPVTGWV---RSLRHVKPGKYSLKVKSEDRASRLYY 236

Query: 562 SDTTDVEIS-----VVDVNDNEP-----VFKQQLYTANIMEDALVGTSVS-QVGATDADV 610
            D  +V+ S     ++ V + +P     +  Q+    NI+ +  +   ++ +    DA V
Sbjct: 237 FDENEVQPSWTADVLITVRETKPKPRRILVDQRKINPNILNNRQLAAIITLKDSPNDAIV 296

Query: 611 GLNG--RIH-YELDPK-----DREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
           GL G  + H +E++P+       +E  +++   +G           ++    ++      
Sbjct: 297 GLKGNEKEHWFEVEPEVVGNDGTKELRWMLYAKNGSQVPKNTNVTLTIGEDYIRRSGFSI 356

Query: 663 GTPPQSST-VIVHIKIEDINDSPPVF-ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
              P   T   V I+IE + +    F +++ LT    E +PIG  +  +  +  +    +
Sbjct: 357 SKKPVIPTNETVTIQIERLAEHLIRFLDNEKLTLKTDEMAPIGRILYRMNVNVENPDDVS 416

Query: 721 VVHYSIK-GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV--IRAASPPL-WN 776
           ++ YS++    D  + +L    GS    L     ++       ++++  +   +  L   
Sbjct: 417 LIRYSLEYSKSDLPNATLPFAIGSKNGILRVSAKINRSERVYNFKVIASLHGINEKLAEK 476

Query: 777 DVRVEILVTDVNDNAPV 793
           DV +EIL  D ND+APV
Sbjct: 477 DVSIEIL--DSNDHAPV 491



 Score = 43.2 bits (97), Expect = 0.11
 Identities = 14/32 (43%), Positives = 20/32 (62%)

Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C+S+PC  G +C   ++ Y+C C  G TGK C
Sbjct: 3951 CASSPCPTGIQCIPFYNDYLCKCPNGFTGKHC 3982



 Score = 41.9 bits (94), Expect = 0.25
 Identities = 21/54 (38%), Positives = 35/54 (64%), Gaps = 2/54 (3%)

Query: 11  INVLDCNDHSPVFEM--QQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
           + V+D ND SPVF +  Q YEA + +     +TVL ++A+D DIG N+ + +++
Sbjct: 141 LRVIDRNDASPVFLVGEQGYEAEIDDDLEPFSTVLRVEASDADIGINSAIYFSL 194


>UniRef50_UPI000065CB4F Cluster: Protocadherin-9 precursor.; n=2;
           Euteleostomi|Rep: Protocadherin-9 precursor. - Takifugu
           rubripes
          Length = 1011

 Score =  285 bits (698), Expect = 2e-74
 Identities = 194/623 (31%), Positives = 302/623 (48%), Gaps = 31/623 (4%)

Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195
           I + + D NDN P F      +S+ E+  +  N   A   ATD D G NS  +Y +I G 
Sbjct: 129 IKIIVKDTNDNAPMFPSPVINISIPENTLI--NSRFAIPSATDPDTGPNSVHKYELINGQ 186

Query: 196 TQMQFSI-DSLSGD----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
           +     I ++  G+    + + + LD EQ  +Y + I+ +DGGSP +S+T  L + + DV
Sbjct: 187 SAFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGSPQKSSTAILQVTVTDV 246

Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
           NDN P F     +  + EN  IG S+V++QA DAD G NAE+ Y    +       L   
Sbjct: 247 NDNRPVFKEGQIEVHIPENSAIGTSVVQLQATDADIGANAEIHYVFGTQVSPATKRL-FA 305

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX----XXXXXXXF 366
           ++  SG +     LDRE  A ++L V A+DG   P  AT T                   
Sbjct: 306 LNSTSGLITVQRPLDREETAIHKLSVLASDGSSSPARATVTINVTDVNDNPPNIDLRYII 365

Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQNGRGLITV 425
            P    V L+E +P  T +  +T +D D D N         +          N + L+  
Sbjct: 366 SPINGTVFLSEKDPINTKIALITVSDKDTDINGKVICFIEKDVPFHLKAVYDN-QYLLET 424

Query: 426 AQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
           +  LD++  + Y   + A+DSG  S   TA+V++ + D N+ AP+F       +V E+  
Sbjct: 425 SALLDYEGTKEYNFKIVASDSGKPSLNQTALVRVRLEDENDNAPIFTQPVIELAVMENNK 484

Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
               +  +SATD D G NA+I Y L    S          F ++ +TG +T +++ DRE 
Sbjct: 485 RDLFLTTISATDEDSGKNAEIVYQLGPNAS---------FFDLDRKTGVLTASRVFDRED 535

Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
              +L TVTARD G P L     V ++V+D NDN P F    +   + E+    ++V  +
Sbjct: 536 QDRFLFTVTARDNGTPPLQTQATVIVTVLDENDNNPKFTHNHFQFFVSENLPKYSTVGVI 595

Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
             TD+D G N  +   +   D E  +F++DP SGVI++N + DRE  +++     A+D G
Sbjct: 596 TVTDSDAGENAAVSLSI-LNDNE--NFILDPFSGVIKSNVSFDREQQSSYTFDVRAVDSG 652

Query: 664 TPPQSSTVIVHIKIEDINDSPP--VFESDCLTFYISENSPI-GTTIGEIRAHDPDEGPNA 720
            PP SS   V I + D+ND+ P  ++     +F +   S I G+ + E+ A D D G NA
Sbjct: 653 RPPCSSAAKVTINVIDVNDNTPIVIYPPSNTSFKLVPLSSIPGSVVAEVFAVDGDTGMNA 712

Query: 721 VVHYSIKGGDDSNSFSLETRQGS 743
            + Y+I  G++   F ++   G+
Sbjct: 713 ELKYTIVSGNNKGLFRIDPVTGN 735



 Score =  269 bits (660), Expect = 6e-70
 Identities = 200/656 (30%), Positives = 306/656 (46%), Gaps = 51/656 (7%)

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
           ++ I ++D NDNAP F + +   S+ EN  I        A D D G N+   Y + +   
Sbjct: 128 KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPDTGPNSVHKYELINGQS 187

Query: 302 TGNVDLPITIDPRSGW--VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
              +D+  T +    W  +     LDRE +  Y + +   DGG P +S+TA         
Sbjct: 188 AFGLDIVETPEGEK-WPQLIVQQNLDREQKDTYVMKIKVEDGGSPQKSSTAILQVTVTDV 246

Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEI---TGGNTRGRFSI 414
                 F  GQ EV + E+   GT VV L ATDAD   +  +HY         T+  F++
Sbjct: 247 NDNRPVFKEGQIEVHIPENSAIGTSVVQLQATDADIGANAEIHYVFGTQVSPATKRLFAL 306

Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFE---- 470
            S +  GLITV +PLD ++   + L+V A+D       A V IN+TD N+  P  +    
Sbjct: 307 NSTS--GLITVQRPLDREETAIHKLSVLASDGSSSPARATVTINVTDVNDNPPNIDLRYI 364

Query: 471 NAPYTASVF--EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528
            +P   +VF  E  PI T + +++ +D D  IN ++   +  ++     A +D Q+++  
Sbjct: 365 ISPINGTVFLSEKDPINTKIALITVSDKDTDINGKVICFIEKDVPFHLKAVYDNQYLLE- 423

Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588
                 T+ LLD E    Y   + A D G PSL+ T  V + + D NDN P+F Q +   
Sbjct: 424 ------TSALLDYEGTKEYNFKIVASDSGKPSLNQTALVRVRLEDENDNAPIFTQPVIEL 477

Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648
            +ME+      ++ + ATD D G N  I Y+L P       F +D  +GV+  ++  DRE
Sbjct: 478 AVMENNKRDLFLTTISATDEDSGKNAEIVYQLGP---NASFFDLDRKTGVLTASRVFDRE 534

Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
                     A D GTPP  +   V + + D ND+ P F  +   F++SEN P  +T+G 
Sbjct: 535 DQDRFLFTVTARDNGTPPLQTQATVIVTVLDENDNNPKFTHNHFQFFVSENLPKYSTVGV 594

Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768
           I   D D G NA V  SI   +D+ +F L+   G  K+     V  D E  +  Y   +R
Sbjct: 595 ITVTDSDAGENAAVSLSIL--NDNENFILDPFSGVIKSN----VSFDREQ-QSSYTFDVR 647

Query: 769 AAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVP-------- 817
           A     PP  +  +V I V DVNDN P+     +I+      F + P   +P        
Sbjct: 648 AVDSGRPPCSSAAKVTINVIDVNDNTPI-----VIYPPSNTSFKLVPLSSIPGSVVAEVF 702

Query: 818 AYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
           A D D  +  +L+Y I+SGNN  L  ++  TG++TL  +       L  + V+++D
Sbjct: 703 AVDGDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAVTDIGLHRLVVNISD 758



 Score =  237 bits (581), Expect = 2e-60
 Identities = 197/716 (27%), Positives = 326/716 (45%), Gaps = 59/716 (8%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +I V D ND++P+F       S+ E     +      ATD D G N+  +Y +       
Sbjct: 130 KIIVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPDTGPNSVHKYEL------- 182

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
           +N + A           +       +   L+ + +LDRE+   Y + +K  D  SP   +
Sbjct: 183 INGQSAFGLDIVETPEGE-------KWPQLIVQQNLDREQKDTYVMKIKVEDGGSP---Q 232

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            SSTA + V + D NDN P F E    V + E+ ++  +  + +++ATDAD+GAN+ I Y
Sbjct: 233 KSSTAILQVTVTDVNDNRPVFKEGQIEVHIPENSAIGTS--VVQLQATDADIGANAEIHY 290

Query: 190 AI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG-GSPSRSNTTQLLI 245
                +   T+  F+++S SG +++ + LD E+   ++L + A DG  SP+R+  T   I
Sbjct: 291 VFGTQVSPATKRLFALNSTSGLITVQRPLDREETAIHKLSVLASDGSSSPARATVT---I 347

Query: 246 NIRDVNDNAP----RFYTSLFQESV--SENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
           N+ DVNDN P    R+  S    +V  SE  PI   I  +   D D  +N ++     +K
Sbjct: 348 NVTDVNDNPPNIDLRYIISPINGTVFLSEKDPINTKIALITVSDKDTDINGKV-ICFIEK 406

Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
           D   ++     +      + TS  LD E   +Y   + A+D G P  + TA         
Sbjct: 407 DVPFHLK---AVYDNQYLLETSALLDYEGTKEYNFKIVASDSGKPSLNQTALVRVRLEDE 463

Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG 419
                 F     E+ + E+      + T++ATD D           G     F +  +  
Sbjct: 464 NDNAPIFTQPVIELAVMENNKRDLFLTTISATDEDSGKNAEIVYQLGPNASFFDLDRKT- 522

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477
            G++T ++  D + + R++ TV+A D+G       A V + + D N+  P F +  +   
Sbjct: 523 -GVLTASRVFDREDQDRFLFTVTARDNGTPPLQTQATVIVTVLDENDNNPKFTHNHFQFF 581

Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
           V E+ P  +TV V++ TDSD G NA ++ S+ ++         ++ F+++P +G I +N 
Sbjct: 582 VSENLPKYSTVGVITVTDSDAGENAAVSLSILND---------NENFILDPFSGVIKSNV 632

Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN---IMEDA 594
             DRE  S Y   V A D G P  S    V I+V+DVNDN P+        +   +   +
Sbjct: 633 SFDREQQSSYTFDVRAVDSGRPPCSSAAKVTINVIDVNDNTPIVIYPPSNTSFKLVPLSS 692

Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654
           + G+ V++V A D D G+N  + Y +      +G F IDP +G I   +      +  H 
Sbjct: 693 IPGSVVAEVFAVDGDTGMNAELKYTI-VSGNNKGLFRIDPVTGNITLEEKPAVTDIGLHR 751

Query: 655 LKAVAIDGGTPPQSST-VIVHIKIED-INDSPPVFESDCLTFYISENSPIGTTIGE 708
           L     D G P    T V+V + + D + +S  +++    T      +PI   IGE
Sbjct: 752 LVVNISDLGYPKSLHTLVLVFLYVNDTVGNSTLIYDLIRRTM----ETPIDRNIGE 803



 Score = 88.2 bits (209), Expect = 3e-15
 Identities = 78/302 (25%), Positives = 137/302 (45%), Gaps = 20/302 (6%)

Query: 590 IMEDALVGTSVSQ--VGATDADVGLNGRIHYELDPKDREEGSFVIDPASG-VIRTNKALD 646
           + E+ L+G       +  T+A  G++  + Y L  K  +     +  ++G +  T+  +D
Sbjct: 36  LQENVLIGNIPKDLNISHTNAATGVSANLVYRLVSKAGDNPLVRVLSSTGEIFTTSNRID 95

Query: 647 RESVAT----HDLK-AVAIDGGTPPQSSTVIVHIKI--EDINDSPPVFESDCLTFYISEN 699
           RE +       D + +  I+    P     ++ IKI  +D ND+ P+F S  +   I EN
Sbjct: 96  REKLCPGPSFEDSECSFEIEVVILPNDYFRLIKIKIIVKDTNDNAPMFPSPVINISIPEN 155

Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL-ETRQGSDKAELVTMVDLDYES 758
           + I +      A DPD GPN+V  Y +  G  +    + ET +G    +L+   +LD E 
Sbjct: 156 TLINSRFAIPSATDPDTGPNSVHKYELINGQSAFGLDIVETPEGEKWPQLIVQQNLDREQ 215

Query: 759 PRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR 815
            +  Y + I+     SP   +   +++ VTDVNDN PV K+ QI  +  ++        +
Sbjct: 216 -KDTYVMKIKVEDGGSPQKSSTAILQVTVTDVNDNRPVFKEGQIEVHIPENSAIGTSVVQ 274

Query: 816 VPAYDADVTDKLQYRILSGNNAN-----LILLNETTGSMTLSPQLNTNVPKLATMEVSVT 870
           + A DAD+    +   + G   +     L  LN T+G +T+   L+     +  + V  +
Sbjct: 275 LQATDADIGANAEIHYVFGTQVSPATKRLFALNSTSGLITVQRPLDREETAIHKLSVLAS 334

Query: 871 DG 872
           DG
Sbjct: 335 DG 336


>UniRef50_Q4SVM9 Cluster: Chromosome 1 SCAF13750, whole genome shotgun
            sequence; n=11; Clupeocephala|Rep: Chromosome 1
            SCAF13750, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 4362

 Score =  281 bits (688), Expect = 3e-73
 Identities = 249/884 (28%), Positives = 385/884 (43%), Gaps = 81/884 (9%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I +LD ND++P  E+  +  +V E +  GTTV  +  +D+D G N +V   I       
Sbjct: 2241 KITILDLNDNAPEIEVTSFSKAVPEDSKPGTTVALISVSDKDSGVNGKVICFINEDVPFM 2300

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            L+P                   +     +++T++ LDRE  ++Y + + A D        
Sbjct: 2301 LSPT------------------LQANMYSVVTKSVLDREHESKYDITITAKDAGD---QP 2339

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            LSS  TI V++ D NDN P+F    YT  V E+        +  + A D D   NS I Y
Sbjct: 2340 LSSHRTISVSVSDVNDNSPEFVTNPYTFYVTENND--PGTTLFSVSAQDCDERDNSLISY 2397

Query: 190  AIIGGNTQMQ-----FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
             II    Q Q      +I+S +G +S +K+ D+E  + ++  + A D GSPS S+   + 
Sbjct: 2398 NIIRNGNQHQAITSFLNINSENGQISALKSFDFEAQKMFQFQVVASDSGSPSLSSNVTVK 2457

Query: 245  INIRDVNDNAPRFYTSLFQ-------ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297
            + I D NDNAP     +         E +  NV  G+ + +V+AYDAD G N  L + + 
Sbjct: 2458 VFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFALQ 2517

Query: 298  DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX- 356
            +     +  L   +D  +G + T        +A+++L++   D G+   SATAT      
Sbjct: 2518 E---VSDHSL-FGLDRYTGQIRTLRSFTETDEAEHKLVILVKDNGNVSLSATATVLVKLV 2573

Query: 357  ----XXXXXXXXXFMPGQY------------EVELAEDEPPGTPVVTLTATDADEDNRLH 400
                         F PG+              VE+    P G+    L    +   +R  
Sbjct: 2574 EPKEAFAASDCSKFCPGRRGRSPEDGLDVVRRVEIQIGHPVGSVAKDLGLDISTLADR-R 2632

Query: 401  YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ---ERRYVLTVSATDSGGRSDTAMVQI 457
            + I  G     F +   NG  ++ V + +D ++     +  L           +   V +
Sbjct: 2633 FRIVPGPNHHLFQLNQDNG--VLYVGKNIDREELCDGTKVCLINLKIVVESPLEIHYVGV 2690

Query: 458  NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517
             I D N++AP F  +     + E  P GT   + +A D D       +Y LS     +  
Sbjct: 2691 EIADVNDHAPSFPESEQRLEIAEHTPPGTRFQIHAARDPDAATLTVRSYKLSHNDCFDID 2750

Query: 518  AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577
                ++  I      +   K LDRE  + + LT+TA DGG PS S + ++ I V+D NDN
Sbjct: 2751 IRESEEDKIP----FLVLKKPLDREQKAQHSLTLTALDGGNPSRSGSLNLTIEVLDTNDN 2806

Query: 578  EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDREEGSFVIDPA 635
             PVF + +Y  ++ E+A  GT V Q+ ATD D GLNG I Y      K + + +F +D  
Sbjct: 2807 RPVFSKDIYLVSLDENAQRGTLVVQLNATDLDEGLNGEIEYSFGKTQKKKVQDTFELDSV 2866

Query: 636  SGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695
            +G IR    +D E      L   A D G  P ++   V IKI+DIND+ P  E   L+  
Sbjct: 2867 TGEIRVKGNVDFEETEVFRLDIQASDKGHLPWTAESRVVIKIKDINDNRPEIEITSLSTS 2926

Query: 696  ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755
            + E++  GT I  I   D D G N  V   I G      F L      +   LVT   LD
Sbjct: 2927 VPEDAKPGTVISLISIRDKDSGLNGKVICKISG---DVPFDLTPSIEENMYSLVTKGRLD 2983

Query: 756  YESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP 812
             E     Y+++I A     PPL     + + V+DVNDN PV           ++  P   
Sbjct: 2984 RERV-AHYDIIITATDCGDPPLSAVKSLTVYVSDVNDNRPVFNQNPFELYLVENNAPGAS 3042

Query: 813  FGRVPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTLSPQ 854
               V A D D+ +   + Y I+ G+     LLN+ T  + ++ +
Sbjct: 3043 IFSVSAVDDDLNENALVNYNIIRGDG----LLNDLTAFLNINSE 3082



 Score =  250 bits (613), Expect = 3e-64
 Identities = 230/824 (27%), Positives = 370/824 (44%), Gaps = 77/824 (9%)

Query: 93   DGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSE 152
            D  S  L+ +  LDREK    ++ + A D  +P     S T+ I ++++D NDN P FS 
Sbjct: 3333 DRTSAHLVLQKQLDREKQDVISLTLTALDGGNPPK---SGTSQIIISVLDINDNAPVFSR 3389

Query: 153  KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII--GGNTQMQ-FSIDSLSGDV 209
              Y   + E+I      ++  + ATD D   N+ I +++   G N  +  F ID  SG +
Sbjct: 3390 SLYKAQIPENIQAGTTVIV--LNATDEDKELNAEIEFSLRSKGQNDVLDLFRIDPKSGAI 3447

Query: 210  SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269
             +   +DYE+  ++ +  +A D G P  S   ++L+ + DVNDNAP    +    +V E+
Sbjct: 3448 LVNGKIDYEENPAFEIHAQASDKGQPPMSTDCKVLVEVLDVNDNAPEITVTPLLSTVKED 3507

Query: 270  VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT---SGQLDR 326
              +G +I  V   D D G N  +   + +        +P  +D      Y+   +G LDR
Sbjct: 3508 AEVGTAIALVSVLDKDGGKNGIVRAAIAN-------HVPFKLDTNYKNYYSLVVNGALDR 3560

Query: 327  ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386
            E+QA++ + + A D G PP S+T+T              F+     + + E+ P G  + 
Sbjct: 3561 ESQAQFNVTIVACDEGAPPLSSTSTVAVQVSDVNDNAPRFLEQAINIYVKENSPVGATMK 3620

Query: 387  TLTATDADED--NRLHYEITGGNTRGR---FSITSQNGRGLITVAQPLDFKQERRYVLTV 441
            T+TA DAD D   ++ Y     N+  +     I   +  G I   Q  D+++ + +   V
Sbjct: 3621 TITAVDADVDQSGQVRYSYLQRNSESQPLSSMININSETGDIVSLQSFDYEELKTFQFQV 3680

Query: 442  SATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499
             ATDSG    S    V + I D N+  P    APY+    E   + TTV  +     + G
Sbjct: 3681 QATDSGVPPLSSNVSVNVFILDENDNNPAI-LAPYS----EHGSVNTTV-SIEVVVVESG 3734

Query: 500  INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
             + Q  +  +  +  E+ +  D    +     A++   LL   T+       T  DGG+ 
Sbjct: 3735 ADIQTPFRHNVPVKEESFS--DLNLYLLIAIVAVSAIFLLSLITLIAVRCHRT--DGGLG 3790

Query: 560  SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619
            S S                      LY A I E+   GT+V  + ATD D  LN  I + 
Sbjct: 3791 SRS----------------------LYKAQIPENTQAGTTVIVLNATDEDKELNAEIEFS 3828

Query: 620  LDPKDREE--GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
            L  K + +    F IDP SG I  N  +D E     ++ A A D G PP S+   V +++
Sbjct: 3829 LRSKGQNDVLDLFRIDPKSGAILVNGKIDYEENPAFEIHAQASDKGQPPMSTDCKVLVEV 3888

Query: 678  EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL 737
             D+ND+ P      L   + E++ +GT I  +   D D G N +V  +I    +   F L
Sbjct: 3889 LDVNDNAPEITVTSLLSTVKEDAEVGTAIALVSVLDKDGGKNGIVRAAIA---NHVPFKL 3945

Query: 738  ETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVM 794
            +T    +   LV    LD ES + ++ + I A    +PPL +   V + V+DVNDNAP  
Sbjct: 3946 DTNY-KNYYSLVVNGALDRES-QAQFNVTIVACDEGAPPLSSTSTVAVQVSDVNDNAPRF 4003

Query: 795  KDFQIIFNNYKDCFPVG-PFGRVPAYDADV--TDKLQYRILSGNN-----ANLILLNETT 846
             + Q I    K+  PVG     + A DADV  + +++Y  L  N+     +++I +N  T
Sbjct: 4004 LE-QAINIYVKENSPVGATMKTITAVDADVDQSGQVRYSYLQSNSESQPLSSMININSET 4062

Query: 847  GSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITE 889
            G +      +    K    +V  TD GV  + + + ++V ++ E
Sbjct: 4063 GDIVSLQSFDYEELKTFQFQVQATDSGVPPLSSNVSVNVFILDE 4106



 Score =  243 bits (594), Expect = 6e-62
 Identities = 212/809 (26%), Positives = 356/809 (44%), Gaps = 47/809 (5%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            ++V D ND+SP F    Y   V E    GTT+ ++ A D D   N+ + Y I        
Sbjct: 2348 VSVSDVNDNSPEFVTNPYTFYVTENNDPGTTLFSVSAQDCDERDNSLISYNI----IRNG 2403

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N   A          +     I+  +G +    S D E    +   V A+D  SP    L
Sbjct: 2404 NQHQA----------ITSFLNINSENGQISALKSFDFEAQKMFQFQVVASDSGSP---SL 2450

Query: 131  SSTATIHVNIIDDNDN-----YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
            SS  T+ V I+D NDN     YP  S  +     +   +V    ++ K++A DAD+G N 
Sbjct: 2451 SSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGYNG 2510

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
             + +A+   +    F +D  +G +  +++        ++LVI  +D G+ S S T  +L+
Sbjct: 2511 WLLFALQEVSDHSLFGLDRYTGQIRTLRSFTETDEAEHKLVILVKDNGNVSLSATATVLV 2570

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPI-GYSIVR---VQAYDADEGVNAELTY---TMTD 298
             + +  +       S F        P  G  +VR   +Q       V  +L     T+ D
Sbjct: 2571 KLVEPKEAFAASDCSKFCPGRRGRSPEDGLDVVRRVEIQIGHPVGSVAKDLGLDISTLAD 2630

Query: 299  KDYT---GNVDLPITIDPRSGWVYTSGQLDRET--QAKYQLLVTATDGGDPPRSATATXX 353
            + +    G       ++  +G +Y    +DRE         L+      + P        
Sbjct: 2631 RRFRIVPGPNHHLFQLNQDNGVLYVGKNIDREELCDGTKVCLINLKIVVESPLEIHYVGV 2690

Query: 354  XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRL--HYEITGGNTRGR 411
                        F   +  +E+AE  PPGT      A D D        Y+++  +    
Sbjct: 2691 EIADVNDHAPS-FPESEQRLEIAEHTPPGTRFQIHAARDPDAATLTVRSYKLSHNDCFDI 2749

Query: 412  FSITSQNGR-GLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPV 468
                S+  +   + + +PLD +Q+ ++ LT++A D G   RS +  + I + D N+  PV
Sbjct: 2750 DIRESEEDKIPFLVLKKPLDREQKAQHSLTLTALDGGNPSRSGSLNLTIEVLDTNDNRPV 2809

Query: 469  FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528
            F    Y  S+ E+A  GT V+ ++ATD D G+N +I YS       +        F ++ 
Sbjct: 2810 FSKDIYLVSLDENAQRGTLVVQLNATDLDEGLNGEIEYSFGKTQKKKV----QDTFELDS 2865

Query: 529  QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588
             TG I     +D E    + L + A D G    +  + V I + D+NDN P  +    + 
Sbjct: 2866 VTGEIRVKGNVDFEETEVFRLDIQASDKGHLPWTAESRVVIKIKDINDNRPEIEITSLST 2925

Query: 589  NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648
            ++ EDA  GT +S +   D D GLNG++  ++      + +  I+     + T   LDRE
Sbjct: 2926 SVPEDAKPGTVISLISIRDKDSGLNGKVICKISGDVPFDLTPSIEENMYSLVTKGRLDRE 2985

Query: 649  SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
             VA +D+   A D G PP S+   + + + D+ND+ PVF  +    Y+ EN+  G +I  
Sbjct: 2986 RVAHYDIIITATDCGDPPLSAVKSLTVYVSDVNDNRPVFNQNPFELYLVENNAPGASIFS 3045

Query: 709  IRAHDPDEGPNAVVHYSIKGGDDS-NSFSLETRQGSDKAELVTMVDLDYESPRK-KYELV 766
            + A D D   NA+V+Y+I  GD   N  +      S+  ++  +   D+E+ +  ++++V
Sbjct: 3046 VSAVDDDLNENALVNYNIIRGDGLLNDLTAFLNINSENGQISALKSFDFETLKTFQFQVV 3105

Query: 767  IR-AASPPLWNDVRVEILVTDVNDNAPVM 794
               + SP L ++V V++ + D NDNAPV+
Sbjct: 3106 ASDSGSPSLSSNVTVKVFILDQNDNAPVI 3134



 Score =  231 bits (566), Expect = 2e-58
 Identities = 225/840 (26%), Positives = 361/840 (42%), Gaps = 82/840 (9%)

Query: 4    PFCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
            P  +H   + VLD NDHSP F + Q    + E A  G       A D D    +   Y +
Sbjct: 2017 PLEVHYVAVEVLDVNDHSPTFSVNQTRLEISESALPGARFQLQGAHDPDSDAYSIQLYKL 2076

Query: 63   ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122
                   L  +D                  DG+   L     LD+E    +T+++ A D 
Sbjct: 2077 SQNEHFRLEVKDRGD---------------DGKIPVLYLHKPLDKETARSHTLVLTAADG 2121

Query: 123  ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
              P     S T TI + ++D NDN P F++++Y   + E+  +     + ++ ATD D G
Sbjct: 2122 GKPAR---SGTMTIKITVLDVNDNMPVFAKESYVAVLRENSPI--GTTVLQVNATDLDDG 2176

Query: 183  ANSAIRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239
             N  + Y+    +    +  F ID+ +G++ +   +DYE    Y + I+A D GS     
Sbjct: 2177 LNGEVVYSFGNNVNHRLRKLFEIDADTGEIIVKGQIDYEMKDRYEIDIKASDKGSAPLET 2236

Query: 240  TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE-LTYTMTD 298
               + I I D+NDNAP    + F ++V E+   G ++  +   D D GVN + + +   D
Sbjct: 2237 EKSVKITILDLNDNAPEIEVTSFSKAVPEDSKPGTTVALISVSDKDSGVNGKVICFINED 2296

Query: 299  KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358
              +     L  T+      V T   LDRE ++KY + +TA D GD P S+  T       
Sbjct: 2297 VPFM----LSPTLQANMYSVVTKSVLDREHESKYDITITAKDAGDQPLSSHRTISVSVSD 2352

Query: 359  XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DNRL--HYEITGGNTR----GR 411
                   F+   Y   + E+  PGT + +++A D DE DN L  +  I  GN        
Sbjct: 2353 VNDNSPEFVTNPYTFYVTENNDPGTTLFSVSAQDCDERDNSLISYNIIRNGNQHQAITSF 2412

Query: 412  FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVF 469
             +I S+NG+  I+  +  DF+ ++ +   V A+DSG    S    V++ I D N+ APV 
Sbjct: 2413 LNINSENGQ--ISALKSFDFEAQKMFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVI 2470

Query: 470  ---ENAPYTASVFEDAP----IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522
                ++  +A   E+ P     G  V  V A D+D+G N  + ++L  E+S+ ++     
Sbjct: 2471 LYPVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFAL-QEVSDHSL----- 2524

Query: 523  QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582
             F ++  TG I T +       + + L +  +D G  SLS T  V + +V+  +      
Sbjct: 2525 -FGLDRYTGQIRTLRSFTETDEAEHKLVILVKDNGNVSLSATATVLVKLVEPKEAFAASD 2583

Query: 583  QQLY----TANIMEDAL-----VGTSVSQ-VGATDADVGLN----GRIHYELDPKDREEG 628
               +         ED L     V   +   VG+   D+GL+        + + P      
Sbjct: 2584 CSKFCPGRRGRSPEDGLDVVRRVEIQIGHPVGSVAKDLGLDISTLADRRFRIVPGPNHH- 2642

Query: 629  SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI--VHIKIEDINDSPPV 686
             F ++  +GV+   K +DRE +     K   I+     +S   I  V ++I D+ND  P 
Sbjct: 2643 LFQLNQDNGVLYVGKNIDREELC-DGTKVCLINLKIVVESPLEIHYVGVEIADVNDHAPS 2701

Query: 687  FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG-SDK 745
            F        I+E++P GT      A DPD     V  Y +   D    F ++ R+   DK
Sbjct: 2702 FPESEQRLEIAEHTPPGTRFQIHAARDPDAATLTVRSYKLSHND---CFDIDIRESEEDK 2758

Query: 746  AE-LVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVM-KDFQII 800
               LV    LD E  + ++ L + A    +P     + + I V D NDN PV  KD  ++
Sbjct: 2759 IPFLVLKKPLDREQ-KAQHSLTLTALDGGNPSRSGSLNLTIEVLDTNDNRPVFSKDIYLV 2817



 Score =  222 bits (542), Expect = 1e-55
 Identities = 190/669 (28%), Positives = 302/669 (45%), Gaps = 57/669 (8%)

Query: 117  VKATDQASPVSDRLSSTATIHVNIIDDNDN-----YPQFSEKTYTVSVDEDISVTDNPVI 171
            V A+D  SP    LSS  T+ V I+D NDN     YP  S  +     +   +V    ++
Sbjct: 370  VVASDSGSP---SLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLV 426

Query: 172  AKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD 231
             K++A DAD+G N  + +A+   +    F +D  +G +  +++        ++LVI  +D
Sbjct: 427  TKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTGQIRTLRSFTETDEAEHKLVILVKD 486

Query: 232  GGSPSRSNTTQLLINI----------------RDVNDNAPRFYTSLFQESVSENVPIGYS 275
             G+ S S T  +L+ +                +D  D+   FY  +   SVS    I   
Sbjct: 487  NGNVSLSATATVLVKLVEPKEAFAASDVQSSAQDDEDSHVTFYLMITLGSVSVLFVISII 546

Query: 276  IVRVQAYDADE------GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329
            ++    Y + +      G    +  T+    +   + LP   D R         LDRE  
Sbjct: 547  VLIAMQYRSGDKRYMLVGPRMSIGSTIVPGSHANTLVLP---DRRR--TNEERLLDREKL 601

Query: 330  AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389
             ++ L++TA DGG+PPRS T                F    Y  ++ E+   GT V+ + 
Sbjct: 602  REHHLILTAVDGGNPPRSGTLNVTVIVLDSNDNHPIFSQEVYSADVPENVAAGTSVIKVK 661

Query: 390  ATDADE--DNRLHYEITGGNTRGRFSITSQNGR-GLITVAQPLDFKQERRYVLTVSATDS 446
            ATD DE  +  + Y   G   R  F I   N   G I V   +DF++   + L V ATD 
Sbjct: 662  ATDLDEGANGEIEYFFGGQQDRRTFDIFDLNKETGEIKVKGGIDFEKVEVFKLDVHATDK 721

Query: 447  GG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504
            G    S    V I + D N+ AP  E    +  V ED+  GT + ++S TD D G+N ++
Sbjct: 722  GQPPMSTDCTVIIKVLDQNDNAPQIEVTSLSNVVPEDSKPGTVISLISITDLDAGLNGKV 781

Query: 505  TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT 564
              SLS        +  D +        ++   + LDRE++S Y +T+TA D G P+LSD 
Sbjct: 782  MCSLSDN------SPFDLKPSFQENMYSLVLKQPLDRESVSHYDVTITATDCGQPALSDF 835

Query: 565  TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624
              + I V DVNDN P +        ++E+   G+ +  V A+D D+  N  I Y +  ++
Sbjct: 836  KTLSIDVSDVNDNAPKYSHSPIELYLVENNAPGSQIFSVTASDKDLNENADISYHIIREE 895

Query: 625  REEG---SFV-IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680
              +G   +F+ I+  +G I   K+ D E++ T   + VA D G+P  SS V V + I D 
Sbjct: 896  GGQGKNAAFLNINAENGQISALKSFDFETLKTFQFQVVASDSGSPSLSSNVTVKVFILDQ 955

Query: 681  NDSPPVF----ESDCLTFYISE---NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN 733
            ND+ PV      S+     + E   N   G  + ++RA+D D G N  + ++++   D +
Sbjct: 956  NDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFALQEVSDHS 1015

Query: 734  SFSLETRQG 742
             F L+   G
Sbjct: 1016 LFGLDRYTG 1024



 Score =  216 bits (527), Expect = 8e-54
 Identities = 132/442 (29%), Positives = 227/442 (51%), Gaps = 21/442 (4%)

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDADEDN-RLHYEITGGNTRGRFSITSQNGRGLIT 424
            F   Q  +E++E   PG       A D D D   +       N   R  +  +   G I 
Sbjct: 1283 FSVNQTRLEISESALPGARFQLQGAHDPDSDAYSIQLYKLSQNEHFRLEVKDRGDDGKIP 1342

Query: 425  VA---QPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVF 479
            V    +PLD +  R + L ++A D G   RS T  ++I + D N+  PVF    Y A + 
Sbjct: 1343 VLYLHKPLDKETARSHTLVLTAADGGKPARSGTMTIKITVLDVNDNMPVFAKESYVAVLR 1402

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
            E++PIGTTVL V+ATD D G+N ++ YS  + +++       + F I+  TG I     +
Sbjct: 1403 ENSPIGTTVLQVNATDLDDGLNGEVVYSFGNNVNHRL----RKLFEIDADTGEIIVKGQI 1458

Query: 540  DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
            D E    Y + + A D G   L     V+I+++D+NDN P  +   ++  + ED+  GT+
Sbjct: 1459 DYEMKDRYEIDIKASDKGSAPLETEKSVKITILDLNDNAPEIEVTSFSKAVPEDSKPGTT 1518

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV----IRTNKALDRESVATHDL 655
            V+ +  +D D G+NG++   ++    E+  F++ P        + T   LDRE  + +D+
Sbjct: 1519 VALISVSDKDSGVNGKVICFIN----EDVPFMLSPTLQANMYSVVTKSVLDREHESKYDI 1574

Query: 656  KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
               A D G  P SS   + + + D+ND+ P F ++  TFY++EN+  GTT+  + A D D
Sbjct: 1575 TITAKDAGDQPLSSHRTISVSVSDVNDNSPEFVTNPYTFYVTENNDPGTTLFSVSAQDCD 1634

Query: 716  EGPNAVVHYSI-KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIR-AASP 772
            E  N+++ Y+I + G+   + +      S+  ++  +   D+E+ +  ++++V   + SP
Sbjct: 1635 ERDNSLISYNIIRNGNQHQAITSFLNINSENGQISALKSFDFEAQKMFQFQVVASDSGSP 1694

Query: 773  PLWNDVRVEILVTDVNDNAPVM 794
             L ++V V++ + D NDNAPV+
Sbjct: 1695 SLSSNVTVKVFILDQNDNAPVI 1716



 Score =  214 bits (523), Expect = 3e-53
 Identities = 186/692 (26%), Positives = 306/692 (44%), Gaps = 38/692 (5%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREG-------ASSGTTVLTLKATDQDIGKNAEVEYTI 62
            ++ +LD ND++PV           EG        ++G  V  ++A D DIG N  + + +
Sbjct: 387  KVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFAL 446

Query: 63   ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD- 121
            + V+  +L   D             +    + +   +L + + +    A  TVLVK  + 
Sbjct: 447  QEVSDHSLFGLDRYTGQIRTLRSFTETDEAEHKL-VILVKDNGNVSLSATATVLVKLVEP 505

Query: 122  -QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIA-KIKATDA 179
             +A   SD  SS         DD D++  F       SV     ++   +IA + ++ D 
Sbjct: 506  KEAFAASDVQSSAQ-------DDEDSHVTFYLMITLGSVSVLFVISIIVLIAMQYRSGDK 558

Query: 180  D---VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS 236
                VG   +I   I+ G+      +       +  + LD E++R + L++ A DGG+P 
Sbjct: 559  RYMLVGPRMSIGSTIVPGSHANTLVLPDRRR-TNEERLLDREKLREHHLILTAVDGGNPP 617

Query: 237  RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
            RS T  + + + D NDN P F   ++   V ENV  G S+++V+A D DEG N E+ Y  
Sbjct: 618  RSGTLNVTVIVLDSNDNHPIFSQEVYSADVPENVAAGTSVIKVKATDLDEGANGEIEYFF 677

Query: 297  TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
              +      D+   ++  +G +   G +D E    ++L V ATD G PP S   T     
Sbjct: 678  GGQQDRRTFDI-FDLNKETGEIKVKGGIDFEKVEVFKLDVHATDKGQPPMSTDCTVIIKV 736

Query: 357  XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSIT 415
                              + ED  PGT +  ++ TD D   N         N+      +
Sbjct: 737  LDQNDNAPQIEVTSLSNVVPEDSKPGTVISLISITDLDAGLNGKVMCSLSDNSPFDLKPS 796

Query: 416  SQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAP 473
             Q     + + QPLD +    Y +T++ATD G    SD   + I+++D N+ AP + ++P
Sbjct: 797  FQENMYSLVLKQPLDRESVSHYDVTITATDCGQPALSDFKTLSIDVSDVNDNAPKYSHSP 856

Query: 474  YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV-INPQTGA 532
                + E+   G+ +  V+A+D D+  NA I+Y +   I  E     +  F+ IN + G 
Sbjct: 857  IELYLVENNAPGSQIFSVTASDKDLNENADISYHI---IREEGGQGKNAAFLNINAENGQ 913

Query: 533  ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT----- 587
            I+  K  D ET+  +   V A D G PSLS    V++ ++D NDN PV    + +     
Sbjct: 914  ISALKSFDFETLKTFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAE 973

Query: 588  --ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645
                I  +   G  V++V A DAD+G NG + + L  +  +   F +D  +G IRT ++ 
Sbjct: 974  GLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFALQ-EVSDHSLFGLDRYTGQIRTLRSF 1032

Query: 646  DRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
                 A H L  +  D G    S+T  V +K+
Sbjct: 1033 TETDEAEHKLVILVKDNGNVSLSATATVLVKL 1064



 Score =  213 bits (521), Expect = 4e-53
 Identities = 195/755 (25%), Positives = 327/755 (43%), Gaps = 61/755 (8%)

Query: 89   VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
            +F+++  +G L    ++DRE++   T +     +   V +       + V I D ND+ P
Sbjct: 2643 LFQLNQDNGVLYVGKNIDREELCDGTKVCLINLKI--VVESPLEIHYVGVEIADVNDHAP 2700

Query: 149  QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
             F E    + + E         I   +  DA   A   +R   +  N      I     D
Sbjct: 2701 SFPESEQRLEIAEHTPPGTRFQIHAARDPDA---ATLTVRSYKLSHNDCFDIDIRESEED 2757

Query: 209  ----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
                + L K LD EQ   + L + A DGG+PSRS +  L I + D NDN P F   ++  
Sbjct: 2758 KIPFLVLKKPLDREQKAQHSLTLTALDGGNPSRSGSLNLTIEVLDTNDNRPVFSKDIYLV 2817

Query: 265  SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
            S+ EN   G  +V++ A D DEG+N E+ Y+   K     V     +D  +G +   G +
Sbjct: 2818 SLDENAQRGTLVVQLNATDLDEGLNGEIEYSF-GKTQKKKVQDTFELDSVTGEIRVKGNV 2876

Query: 325  DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
            D E    ++L + A+D G  P +A +                        + ED  PGT 
Sbjct: 2877 DFEETEVFRLDIQASDKGHLPWTAESRVVIKIKDINDNRPEIEITSLSTSVPEDAKPGTV 2936

Query: 385  VVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
            +  ++  D D   + ++  +I+G           +N   L+T  + LD ++   Y + ++
Sbjct: 2937 ISLISIRDKDSGLNGKVICKISGDVPFDLTPSIEENMYSLVTKGR-LDRERVAHYDIIIT 2995

Query: 443  ATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
            ATD G    +A+  + + ++D N+  PVF   P+   + E+   G ++  VSA D D+  
Sbjct: 2996 ATDCGDPPLSAVKSLTVYVSDVNDNRPVFNQNPFELYLVENNAPGASIFSVSAVDDDLNE 3055

Query: 501  NAQITYSLSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
            NA + Y++   I  + + +    F+ IN + G I+  K  D ET+  +   V A D G P
Sbjct: 3056 NALVNYNI---IRGDGLLNDLTAFLNINSENGQISALKSFDFETLKTFQFQVVASDSGSP 3112

Query: 560  SLSDTTDVEISVVDVNDNEPVFKQQLYT-------ANIMEDALVGTSVSQVGATDADVGL 612
            SLS    V++ ++D NDN PV    + +         I  +   G  V++V A DAD+G 
Sbjct: 3113 SLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGY 3172

Query: 613  NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672
            NG + + L  +  +   F +D  +G IRT ++        H L  +  D G    S+T  
Sbjct: 3173 NGWLLFALQ-EVSDHSLFGLDRYTGQIRTLRSFTETDETEHKLVILVKDNGNVSLSATAT 3231

Query: 673  VHIKIEDINDSPPVFES-DCLTFYISENSPIGTTIGEIRAHDPDE-----GPNAVVHYSI 726
            V +K+    D   V +S D  + Y+ E +  GT    I+    D+     GP   +  +I
Sbjct: 3232 VLVKLHHRPDCNAVSKSPDYTSKYVPETNYDGTLCHSIQYRSGDKRYMLVGPRMSIGSTI 3291

Query: 727  KGGDDSNSFSLETR-----QGSDKAELVTMVD-----------------LDYESPRKKYE 764
              G  +N+  L  R     +GS + E + ++                  L  +  R+K +
Sbjct: 3292 VPGSHANTLVLPDRRRTNEEGSHRCECIWLIQFLKKVIKTGDRTSAHLVLQKQLDREKQD 3351

Query: 765  LV------IRAASPPLWNDVRVEILVTDVNDNAPV 793
            ++      +   +PP     ++ I V D+NDNAPV
Sbjct: 3352 VISLTLTALDGGNPPKSGTSQIIISVLDINDNAPV 3386



 Score =  213 bits (520), Expect = 6e-53
 Identities = 160/558 (28%), Positives = 250/558 (44%), Gaps = 24/558 (4%)

Query: 136  IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195
            + V ++D ND+ P FS     + + E  S           A D D  A S   Y +   N
Sbjct: 1269 VAVEVLDVNDHSPTFSVNQTRLEISE--SALPGARFQLQGAHDPDSDAYSIQLYKL-SQN 1325

Query: 196  TQMQFSIDSLSGD-----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
               +  +     D     + L K LD E  RS+ LV+ A DGG P+RS T  + I + DV
Sbjct: 1326 EHFRLEVKDRGDDGKIPVLYLHKPLDKETARSHTLVLTAADGGKPARSGTMTIKITVLDV 1385

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            NDN P F    +   + EN PIG ++++V A D D+G+N E+ Y+    +    +     
Sbjct: 1386 NDNMPVFAKESYVAVLRENSPIGTTVLQVNATDLDDGLNGEVVYSF-GNNVNHRLRKLFE 1444

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            ID  +G +   GQ+D E + +Y++ + A+D G  P     +                   
Sbjct: 1445 IDADTGEIIVKGQIDYEMKDRYEIDIKASDKGSAPLETEKSVKITILDLNDNAPEIEVTS 1504

Query: 371  YEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
            +   + ED  PGT V  ++ +D D   N         +     S T Q     +     L
Sbjct: 1505 FSKAVPEDSKPGTTVALISVSDKDSGVNGKVICFINEDVPFMLSPTLQANMYSVVTKSVL 1564

Query: 430  DFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
            D + E +Y +T++A D+G +  S    + ++++D N+ +P F   PYT  V E+   GTT
Sbjct: 1565 DREHESKYDITITAKDAGDQPLSSHRTISVSVSDVNDNSPEFVTNPYTFYVTENNDPGTT 1624

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETMSG 546
            +  VSA D D   N+ I+Y++   I N         F+ IN + G I+  K  D E    
Sbjct: 1625 LFSVSAQDCDERDNSLISYNI---IRNGNQHQAITSFLNINSENGQISALKSFDFEAQKM 1681

Query: 547  YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT-------ANIMEDALVGTS 599
            +   V A D G PSLS    V++ ++D NDN PV    + +         I  +   G  
Sbjct: 1682 FQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHL 1741

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
            V++V A DAD+G NG + + L  +  +   F +D  +G IRT ++      A H L  + 
Sbjct: 1742 VTKVRAYDADIGYNGWLLFALQ-EVSDHSLFGLDRYTGQIRTLRSFTETDEAEHKLVILV 1800

Query: 660  IDGGTPPQSSTVIVHIKI 677
             D G    S+T  V +K+
Sbjct: 1801 KDNGNVSLSATATVLVKL 1818



 Score =  202 bits (494), Expect = 8e-50
 Identities = 180/646 (27%), Positives = 292/646 (45%), Gaps = 47/646 (7%)

Query: 126  VSDRLSSTATI----HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKI-KATDAD 180
            V  R+S  +TI    H N +   D      E  Y  S+ E++ V    VI  + K    D
Sbjct: 1151 VGPRMSIGSTIVPGSHANTLVLPDRRRTNEELRY--SIPEELGV--GAVIGNVAKDLGLD 1206

Query: 181  VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDGGSPSRS 238
              A +A  + I+ G+++  F + + +G + + + +D E+V  R+   VI  +     +  
Sbjct: 1207 ANALNARGFRIVSGSSEPPFQLSN-NGILHVNRIIDREEVCERAGACVINTKIV-LENPL 1264

Query: 239  NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
                + + + DVND++P F  +  +  +SE+   G       A+D D    +   Y ++ 
Sbjct: 1265 EVHYVAVEVLDVNDHSPTFSVNQTRLEISESALPGARFQLQGAHDPDSDAYSIQLYKLSQ 1324

Query: 299  KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358
             ++          D +   +Y    LD+ET   + L++TA DGG P RS T T       
Sbjct: 1325 NEHFRLEVKDRGDDGKIPVLYLHKPLDKETARSHTLVLTAADGGKPARSGTMTIKITVLD 1384

Query: 359  XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT-----RGRFS 413
                   F    Y   L E+ P GT V+ + ATD D+        + GN      R  F 
Sbjct: 1385 VNDNMPVFAKESYVAVLRENSPIGTTVLQVNATDLDDGLNGEVVYSFGNNVNHRLRKLFE 1444

Query: 414  ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFEN 471
            I +  G   I V   +D++ + RY + + A+D G         V+I I D N+ AP  E 
Sbjct: 1445 IDADTGE--IIVKGQIDYEMKDRYEIDIKASDKGSAPLETEKSVKITILDLNDNAPEIEV 1502

Query: 472  APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
              ++ +V ED+  GTTV ++S +D D G+N ++   ++ ++           F+++P   
Sbjct: 1503 TSFSKAVPEDSKPGTTVALISVSDKDSGVNGKVICFINEDVP----------FMLSPTLQ 1552

Query: 532  A----ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT 587
            A    + T  +LDRE  S Y +T+TA+D G   LS    + +SV DVNDN P F    YT
Sbjct: 1553 ANMYSVVTKSVLDREHESKYDITITAKDAGDQPLSSHRTISVSVSDVNDNSPEFVTNPYT 1612

Query: 588  ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG---SFV-IDPASGVIRTNK 643
              + E+   GT++  V A D D   N  I Y +     +     SF+ I+  +G I   K
Sbjct: 1613 FYVTENNDPGTTLFSVSAQDCDERDNSLISYNIIRNGNQHQAITSFLNINSENGQISALK 1672

Query: 644  ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF----ESDCLTFYISE- 698
            + D E+      + VA D G+P  SS V V + I D ND+ PV      S+     + E 
Sbjct: 1673 SFDFEAQKMFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEI 1732

Query: 699  --NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
              N   G  + ++RA+D D G N  + ++++   D + F L+   G
Sbjct: 1733 PRNVNAGHLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTG 1778



 Score =  202 bits (494), Expect = 8e-50
 Identities = 180/646 (27%), Positives = 292/646 (45%), Gaps = 47/646 (7%)

Query: 126  VSDRLSSTATI----HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKI-KATDAD 180
            V  R+S  +TI    H N +   D      E  Y  S+ E++ V    VI  + K    D
Sbjct: 1905 VGPRMSIGSTIVPGSHANTLVLPDRRRTNEELRY--SIPEELGV--GAVIGNVAKDLGLD 1960

Query: 181  VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDGGSPSRS 238
              A +A  + I+ G+++  F + + +G + + + +D E+V  R+   VI  +     +  
Sbjct: 1961 ANALNARGFRIVSGSSEPPFQLSN-NGILHVNRIIDREEVCERAGACVINTKIV-LENPL 2018

Query: 239  NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
                + + + DVND++P F  +  +  +SE+   G       A+D D    +   Y ++ 
Sbjct: 2019 EVHYVAVEVLDVNDHSPTFSVNQTRLEISESALPGARFQLQGAHDPDSDAYSIQLYKLSQ 2078

Query: 299  KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358
             ++          D +   +Y    LD+ET   + L++TA DGG P RS T T       
Sbjct: 2079 NEHFRLEVKDRGDDGKIPVLYLHKPLDKETARSHTLVLTAADGGKPARSGTMTIKITVLD 2138

Query: 359  XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT-----RGRFS 413
                   F    Y   L E+ P GT V+ + ATD D+        + GN      R  F 
Sbjct: 2139 VNDNMPVFAKESYVAVLRENSPIGTTVLQVNATDLDDGLNGEVVYSFGNNVNHRLRKLFE 2198

Query: 414  ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFEN 471
            I +  G   I V   +D++ + RY + + A+D G         V+I I D N+ AP  E 
Sbjct: 2199 IDADTGE--IIVKGQIDYEMKDRYEIDIKASDKGSAPLETEKSVKITILDLNDNAPEIEV 2256

Query: 472  APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
              ++ +V ED+  GTTV ++S +D D G+N ++   ++ ++           F+++P   
Sbjct: 2257 TSFSKAVPEDSKPGTTVALISVSDKDSGVNGKVICFINEDVP----------FMLSPTLQ 2306

Query: 532  A----ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT 587
            A    + T  +LDRE  S Y +T+TA+D G   LS    + +SV DVNDN P F    YT
Sbjct: 2307 ANMYSVVTKSVLDREHESKYDITITAKDAGDQPLSSHRTISVSVSDVNDNSPEFVTNPYT 2366

Query: 588  ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG---SFV-IDPASGVIRTNK 643
              + E+   GT++  V A D D   N  I Y +     +     SF+ I+  +G I   K
Sbjct: 2367 FYVTENNDPGTTLFSVSAQDCDERDNSLISYNIIRNGNQHQAITSFLNINSENGQISALK 2426

Query: 644  ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF----ESDCLTFYISE- 698
            + D E+      + VA D G+P  SS V V + I D ND+ PV      S+     + E 
Sbjct: 2427 SFDFEAQKMFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEI 2486

Query: 699  --NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
              N   G  + ++RA+D D G N  + ++++   D + F L+   G
Sbjct: 2487 PRNVNAGHLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTG 2532



 Score =  200 bits (488), Expect = 4e-49
 Identities = 166/595 (27%), Positives = 266/595 (44%), Gaps = 62/595 (10%)

Query: 4    PFCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
            P  +H   + VLD NDHSP F + Q    + E A  G       A D D    +   Y +
Sbjct: 1263 PLEVHYVAVEVLDVNDHSPTFSVNQTRLEISESALPGARFQLQGAHDPDSDAYSIQLYKL 1322

Query: 63   ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122
                   L  +D                  DG+   L     LD+E    +T+++ A D 
Sbjct: 1323 SQNEHFRLEVKDRGD---------------DGKIPVLYLHKPLDKETARSHTLVLTAADG 1367

Query: 123  ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
              P     S T TI + ++D NDN P F++++Y   + E+  +     + ++ ATD D G
Sbjct: 1368 GKPAR---SGTMTIKITVLDVNDNMPVFAKESYVAVLRENSPI--GTTVLQVNATDLDDG 1422

Query: 183  ANSAIRYAIIGGNTQMQ----FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238
             N  + Y+  G N   +    F ID+ +G++ +   +DYE    Y + I+A D GS    
Sbjct: 1423 LNGEVVYSF-GNNVNHRLRKLFEIDADTGEIIVKGQIDYEMKDRYEIDIKASDKGSAPLE 1481

Query: 239  NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
                + I I D+NDNAP    + F ++V E+   G ++  +   D D GVN ++   +  
Sbjct: 1482 TEKSVKITILDLNDNAPEIEVTSFSKAVPEDSKPGTTVALISVSDKDSGVNGKVICFI-- 1539

Query: 299  KDYTGNVDLPITIDP----RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354
                 N D+P  + P        V T   LDRE ++KY + +TA D GD P S+  T   
Sbjct: 1540 -----NEDVPFMLSPTLQANMYSVVTKSVLDREHESKYDITITAKDAGDQPLSSHRTISV 1594

Query: 355  XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DNRL--HYEITGGNTRGR 411
                       F+   Y   + E+  PGT + +++A D DE DN L  +  I  GN    
Sbjct: 1595 SVSDVNDNSPEFVTNPYTFYVTENNDPGTTLFSVSAQDCDERDNSLISYNIIRNGNQHQA 1654

Query: 412  FS----ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNY 465
             +    I S+NG+  I+  +  DF+ ++ +   V A+DSG  S      V++ I D N+ 
Sbjct: 1655 ITSFLNINSENGQ--ISALKSFDFEAQKMFQFQVVASDSGSPSLSSNVTVKVFILDQNDN 1712

Query: 466  APVF---ENAPYTASVFEDAP----IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518
            APV     ++  +A   E+ P     G  V  V A D+D+G N  + ++L  E+S+ ++ 
Sbjct: 1713 APVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFALQ-EVSDHSL- 1770

Query: 519  HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
                 F ++  TG I T +       + + L +  +D G  SLS T  V + +V+
Sbjct: 1771 -----FGLDRYTGQIRTLRSFTETDEAEHKLVILVKDNGNVSLSATATVLVKLVE 1820



 Score =  187 bits (455), Expect = 4e-45
 Identities = 133/435 (30%), Positives = 212/435 (48%), Gaps = 35/435 (8%)

Query: 474  YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
            Y A + E+   GTTV+V++ATD D  +NA+I +SL S+  N+ +      F I+P++GAI
Sbjct: 3795 YKAQIPENTQAGTTVIVLNATDEDKELNAEIEFSLRSKGQNDVL----DLFRIDPKSGAI 3850

Query: 534  TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593
              N  +D E    + +   A D G P +S    V + V+DVNDN P        + + ED
Sbjct: 3851 LVNGKIDYEENPAFEIHAQASDKGQPPMSTDCKVLVEVLDVNDNAPEITVTSLLSTVKED 3910

Query: 594  ALVGTSVSQVGATDADVGLNG--------RIHYELDPKDREEGSFVIDPASGVIRTNKAL 645
            A VGT+++ V   D D G NG         + ++LD   +   S V+         N AL
Sbjct: 3911 AEVGTAIALVSVLDKDGGKNGIVRAAIANHVPFKLDTNYKNYYSLVV---------NGAL 3961

Query: 646  DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
            DRES A  ++  VA D G PP SST  V +++ D+ND+ P F    +  Y+ ENSP+G T
Sbjct: 3962 DRESQAQFNVTIVACDEGAPPLSSTSTVAVQVSDVNDNAPRFLEQAINIYVKENSPVGAT 4021

Query: 706  IGEIRAHDPDEGPNAVVHYS-IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764
            +  I A D D   +  V YS ++   +S   S      S+  ++V++   DYE   K ++
Sbjct: 4022 MKTITAVDADVDQSGQVRYSYLQSNSESQPLSSMININSETGDIVSLQSFDYEE-LKTFQ 4080

Query: 765  LVIRAAS---PPLWNDVRVEILVTDVNDNAP-VMKDFQIIFNNYKDCFP----VGPF-GR 815
              ++A     PPL ++V V + + D NDN P ++  +    +   +  P     G F  +
Sbjct: 4081 FQVQATDSGVPPLSSNVSVNVFILDENDNNPAILAPYSEHGSVNSESIPYSAEAGYFVAK 4140

Query: 816  VPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-G 872
            + A D D      L Y +      NL  +  +TG +    +++ N  K   + V V+D G
Sbjct: 4141 IRAVDLDSGYNALLSYHLSEPKGNNLFRMGTSTGEIRTKRRMSDNDLKSHPLVVLVSDNG 4200

Query: 873  VNEIKAMMQLSVRLI 887
               + A + + V ++
Sbjct: 4201 EPSLSATVSIEVVVV 4215



 Score =  184 bits (448), Expect = 3e-44
 Identities = 136/486 (27%), Positives = 229/486 (47%), Gaps = 32/486 (6%)

Query: 105  LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS 164
            LDREK+  + +++ A D  +P     S T  + V ++D NDN+P FS++ Y+  V E+++
Sbjct: 596  LDREKLREHHLILTAVDGGNPPR---SGTLNVTVIVLDSNDNHPIFSQEVYSADVPENVA 652

Query: 165  VTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS---GDVSLVKTLDYEQVR 221
               +  + K+KATD D GAN  I Y   G   +  F I  L+   G++ +   +D+E+V 
Sbjct: 653  AGTS--VIKVKATDLDEGANGEIEYFFGGQQDRRTFDIFDLNKETGEIKVKGGIDFEKVE 710

Query: 222  SYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA 281
             ++L + A D G P  S    ++I + D NDNAP+   +     V E+   G  I  +  
Sbjct: 711  VFKLDVHATDKGQPPMSTDCTVIIKVLDQNDNAPQIEVTSLSNVVPEDSKPGTVISLISI 770

Query: 282  YDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341
             D D G+N ++  +++D       DL  +       +     LDRE+ + Y + +TATD 
Sbjct: 771  TDLDAGLNGKVMCSLSDNS---PFDLKPSFQENMYSLVLKQPLDRESVSHYDVTITATDC 827

Query: 342  GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRL 399
            G P  S   T              +     E+ L E+  PG+ + ++TA+D D  E+  +
Sbjct: 828  GQPALSDFKTLSIDVSDVNDNAPKYSHSPIELYLVENNAPGSQIFSVTASDKDLNENADI 887

Query: 400  HYEIT---GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAM 454
             Y I    GG  +    +      G I+  +  DF+  + +   V A+DSG  S      
Sbjct: 888  SYHIIREEGGQGKNAAFLNINAENGQISALKSFDFETLKTFQFQVVASDSGSPSLSSNVT 947

Query: 455  VQINITDANNYAPVF---ENAPYTASVFEDAP----IGTTVLVVSATDSDVGINAQITYS 507
            V++ I D N+ APV     ++  +A   E+ P     G  V  V A D+D+G N  + ++
Sbjct: 948  VKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFA 1007

Query: 508  LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567
            L  E+S+ ++      F ++  TG I T +       + + L +  +D G  SLS T  V
Sbjct: 1008 LQ-EVSDHSL------FGLDRYTGQIRTLRSFTETDEAEHKLVILVKDNGNVSLSATATV 1060

Query: 568  EISVVD 573
             + +V+
Sbjct: 1061 LVKLVE 1066



 Score =  180 bits (439), Expect = 4e-43
 Identities = 164/678 (24%), Positives = 291/678 (42%), Gaps = 62/678 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V D ND++P F  Q     V+E +  G T+ T+ A D D+ ++ +V Y+     +++ 
Sbjct: 3588 VQVSDVNDNAPRFLEQAINIYVKENSPVGATMKTITAVDADVDQSGQVRYSYLQRNSES- 3646

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             P             +  +  I+  +G +++  S D E++  +   V+ATD   P    L
Sbjct: 3647 QP-------------LSSMININSETGDIVSLQSFDYEELKTFQFQVQATDSGVP---PL 3690

Query: 131  SSTATIHVNIIDDNDNYPQ-FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            SS  +++V I+D+NDN P   +  +   SV+  +S+ +  V+            N  ++ 
Sbjct: 3691 SSNVSVNVFILDENDNNPAILAPYSEHGSVNTTVSI-EVVVVESGADIQTPFRHNVPVKE 3749

Query: 190  AIIGG-NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
                  N  +  +I ++S  + L+  +    VR +R      DGG  SRS          
Sbjct: 3750 ESFSDLNLYLLIAIVAVSA-IFLLSLITLIAVRCHR-----TDGGLGSRS---------- 3793

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
                     Y +   E+      +    + + A D D+ +NAE+ +++  K     +DL 
Sbjct: 3794 --------LYKAQIPENTQAGTTV----IVLNATDEDKELNAEIEFSLRSKGQNDVLDL- 3840

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
              IDP+SG +  +G++D E    +++   A+D G PP S                     
Sbjct: 3841 FRIDPKSGAILVNGKIDYEENPAFEIHAQASDKGQPPMSTDCKVLVEVLDVNDNAPEITV 3900

Query: 369  GQYEVELAEDEPPGTPVVTLTATDAD-EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
                  + ED   GT +  ++  D D   N +       +   +     +N   L+ V  
Sbjct: 3901 TSLLSTVKEDAEVGTAIALVSVLDKDGGKNGIVRAAIANHVPFKLDTNYKNYYSLV-VNG 3959

Query: 428  PLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
             LD + + ++ +T+ A D G    S T+ V + ++D N+ AP F        V E++P+G
Sbjct: 3960 ALDRESQAQFNVTIVACDEGAPPLSSTSTVAVQVSDVNDNAPRFLEQAINIYVKENSPVG 4019

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
             T+  ++A D+DV  + Q+ YS     SN           IN +TG I + +  D E + 
Sbjct: 4020 ATMKTITAVDADVDQSGQVRYSYLQ--SNSESQPLSSMININSETGDIVSLQSFDYEELK 4077

Query: 546  GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF------KQQLYTANIMEDALVGTS 599
             +   V A D GVP LS    V + ++D NDN P           + + +I   A  G  
Sbjct: 4078 TFQFQVQATDSGVPPLSSNVSVNVFILDENDNNPAILAPYSEHGSVNSESIPYSAEAGYF 4137

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
            V+++ A D D G N  + Y L  + +    F +  ++G IRT + +    + +H L  + 
Sbjct: 4138 VAKIRAVDLDSGYNALLSYHLS-EPKGNNLFRMGTSTGEIRTKRRMSDNDLKSHPLVVLV 4196

Query: 660  IDGGTPPQSSTVIVHIKI 677
             D G P  S+TV + + +
Sbjct: 4197 SDNGEPSLSATVSIEVVV 4214



 Score =  175 bits (426), Expect = 1e-41
 Identities = 120/376 (31%), Positives = 191/376 (50%), Gaps = 19/376 (5%)

Query: 429 LDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
           LD ++ R + L ++A D G   RS T  V + + D+N+  P+F    Y+A V E+   GT
Sbjct: 596 LDREKLREHHLILTAVDGGNPPRSGTLNVTVIVLDSNDNHPIFSQEVYSADVPENVAAGT 655

Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
           +V+ V ATD D G N +I Y    +         D    +N +TG I     +D E +  
Sbjct: 656 SVIKVKATDLDEGANGEIEYFFGGQQDRRTFDIFD----LNKETGEIKVKGGIDFEKVEV 711

Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
           + L V A D G P +S    V I V+D NDN P  +    +  + ED+  GT +S +  T
Sbjct: 712 FKLDVHATDKGQPPMSTDCTVIIKVLDQNDNAPQIEVTSLSNVVPEDSKPGTVISLISIT 771

Query: 607 DADVGLNGRIHYELD---PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
           D D GLNG++   L    P D +  SF  +  S V++  + LDRESV+ +D+   A D G
Sbjct: 772 DLDAGLNGKVMCSLSDNSPFDLKP-SFQENMYSLVLK--QPLDRESVSHYDVTITATDCG 828

Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
            P  S    + I + D+ND+ P +    +  Y+ EN+  G+ I  + A D D   NA + 
Sbjct: 829 QPALSDFKTLSIDVSDVNDNAPKYSHSPIELYLVENNAPGSQIFSVTASDKDLNENADIS 888

Query: 724 YSI---KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIR-AASPPLWNDV 778
           Y I   +GG   N+  L     ++  ++  +   D+E+ +  ++++V   + SP L ++V
Sbjct: 889 YHIIREEGGQGKNAAFLNIN--AENGQISALKSFDFETLKTFQFQVVASDSGSPSLSSNV 946

Query: 779 RVEILVTDVNDNAPVM 794
            V++ + D NDNAPV+
Sbjct: 947 TVKVFILDQNDNAPVI 962



 Score =  175 bits (425), Expect = 2e-41
 Identities = 122/408 (29%), Positives = 197/408 (48%), Gaps = 25/408 (6%)

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            T D  S  +    QLDRE Q    L +TA DGG+PP+S T+               F   
Sbjct: 3331 TGDRTSAHLVLQKQLDREKQDVISLTLTALDGGNPPKSGTSQIIISVLDINDNAPVFSRS 3390

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT----GGN-TRGRFSITSQNGRGLIT 424
             Y+ ++ E+   GT V+ L ATD D++     E +    G N     F I  ++G   I 
Sbjct: 3391 LYKAQIPENIQAGTTVIVLNATDEDKELNAEIEFSLRSKGQNDVLDLFRIDPKSGA--IL 3448

Query: 425  VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
            V   +D+++   + +   A+D G    S    V + + D N+ AP     P  ++V EDA
Sbjct: 3449 VNGKIDYEENPAFEIHAQASDKGQPPMSTDCKVLVEVLDVNDNAPEITVTPLLSTVKEDA 3508

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
             +GT + +VS  D D G N  +  ++++ +  +   ++   +       ++  N  LDRE
Sbjct: 3509 EVGTAIALVSVLDKDGGKNGIVRAAIANHVPFKLDTNYKNYY-------SLVVNGALDRE 3561

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
            + + + +T+ A D G P LS T+ V + V DVNDN P F +Q     + E++ VG ++  
Sbjct: 3562 SQAQFNVTIVACDEGAPPLSSTSTVAVQVSDVNDNAPRFLEQAINIYVKENSPVGATMKT 3621

Query: 603  VGATDADVGLNGRIHYELDPKDREE---GSFV-IDPASGVIRTNKALDRESVATHDLKAV 658
            + A DADV  +G++ Y    ++ E     S + I+  +G I + ++ D E + T   +  
Sbjct: 3622 ITAVDADVDQSGQVRYSYLQRNSESQPLSSMININSETGDIVSLQSFDYEELKTFQFQVQ 3681

Query: 659  AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706
            A D G PP SS V V++ I D ND+ P      L  Y SE+  + TT+
Sbjct: 3682 ATDSGVPPLSSNVSVNVFILDENDNNPAI----LAPY-SEHGSVNTTV 3724



 Score =  162 bits (394), Expect = 1e-37
 Identities = 108/345 (31%), Positives = 169/345 (48%), Gaps = 28/345 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I+VLD ND++PVF    Y+A + E   +GTTV+ L ATD+D   NAE+E+++        
Sbjct: 3375 ISVLDINDNAPVFSRSLYKAQIPENIQAGTTVIVLNATDEDKELNAEIEFSLR------- 3427

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           V D+FRID +SGA+L    +D E+   + +  +A+D+  P    +
Sbjct: 3428 ---------SKGQNDVLDLFRIDPKSGAILVNGKIDYEENPAFEIHAQASDKGQP---PM 3475

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S+   + V ++D NDN P+ +      +V ED  V     IA +   D D G N  +R A
Sbjct: 3476 STDCKVLVEVLDVNDNAPEITVTPLLSTVKEDAEV--GTAIALVSVLDKDGGKNGIVRAA 3533

Query: 191  IIGGNTQMQFSID-SLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            I      + F +D +     SLV    LD E    + + I A D G+P  S+T+ + + +
Sbjct: 3534 IA---NHVPFKLDTNYKNYYSLVVNGALDRESQAQFNVTIVACDEGAPPLSSTSTVAVQV 3590

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN-VD 306
             DVNDNAPRF        V EN P+G ++  + A DAD   + ++ Y+   ++     + 
Sbjct: 3591 SDVNDNAPRFLEQAINIYVKENSPVGATMKTITAVDADVDQSGQVRYSYLQRNSESQPLS 3650

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
              I I+  +G + +    D E    +Q  V ATD G PP S+  +
Sbjct: 3651 SMININSETGDIVSLQSFDYEELKTFQFQVQATDSGVPPLSSNVS 3695



 Score =  158 bits (383), Expect = 2e-36
 Identities = 135/495 (27%), Positives = 219/495 (44%), Gaps = 25/495 (5%)

Query: 392  DADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ--ERRYVLTVSATDS-GG 448
            DA+  N   + I  G++   F +++    G++ V + +D ++  ER     ++       
Sbjct: 1206 DANALNARGFRIVSGSSEPPFQLSNN---GILHVNRIIDREEVCERAGACVINTKIVLEN 1262

Query: 449  RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508
              +   V + + D N+++P F        + E A  G    +  A D D    +   Y L
Sbjct: 1263 PLEVHYVAVEVLDVNDHSPTFSVNQTRLEISESALPGARFQLQGAHDPDSDAYSIQLYKL 1322

Query: 509  SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568
            S    NE      +    + +   +  +K LD+ET   + L +TA DGG P+ S T  ++
Sbjct: 1323 SQ---NEHFRLEVKDRGDDGKIPVLYLHKPLDKETARSHTLVLTAADGGKPARSGTMTIK 1379

Query: 569  ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDRE 626
            I+V+DVNDN PVF ++ Y A + E++ +GT+V QV ATD D GLNG + Y    +   R 
Sbjct: 1380 ITVLDVNDNMPVFAKESYVAVLRENSPIGTTVLQVNATDLDDGLNGEVVYSFGNNVNHRL 1439

Query: 627  EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686
               F ID  +G I     +D E    +++   A D G+ P  +   V I I D+ND+ P 
Sbjct: 1440 RKLFEIDADTGEIIVKGQIDYEMKDRYEIDIKASDKGSAPLETEKSVKITILDLNDNAPE 1499

Query: 687  FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746
             E    +  + E+S  GTT+  I   D D G N  V   I   ++   F L     ++  
Sbjct: 1500 IEVTSFSKAVPEDSKPGTTVALISVSDKDSGVNGKVICFI---NEDVPFMLSPTLQANMY 1556

Query: 747  ELVTMVDLDYESPRKKYELVIR---AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN 803
             +VT   LD E    KY++ I    A   PL +   + + V+DVNDN+P        F  
Sbjct: 1557 SVVTKSVLDREH-ESKYDITITAKDAGDQPLSSHRTISVSVSDVNDNSPEFVTNPYTFYV 1615

Query: 804  YKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNN-----ANLILLNETTGSMTLSPQLN 856
             ++  P      V A D D  D   + Y I+   N      + + +N   G ++     +
Sbjct: 1616 TENNDPGTTLFSVSAQDCDERDNSLISYNIIRNGNQHQAITSFLNINSENGQISALKSFD 1675

Query: 857  TNVPKLATMEVSVTD 871
                K+   +V  +D
Sbjct: 1676 FEAQKMFQFQVVASD 1690



 Score =  158 bits (383), Expect = 2e-36
 Identities = 135/495 (27%), Positives = 219/495 (44%), Gaps = 25/495 (5%)

Query: 392  DADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ--ERRYVLTVSATDS-GG 448
            DA+  N   + I  G++   F +++    G++ V + +D ++  ER     ++       
Sbjct: 1960 DANALNARGFRIVSGSSEPPFQLSNN---GILHVNRIIDREEVCERAGACVINTKIVLEN 2016

Query: 449  RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508
              +   V + + D N+++P F        + E A  G    +  A D D    +   Y L
Sbjct: 2017 PLEVHYVAVEVLDVNDHSPTFSVNQTRLEISESALPGARFQLQGAHDPDSDAYSIQLYKL 2076

Query: 509  SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568
            S    NE      +    + +   +  +K LD+ET   + L +TA DGG P+ S T  ++
Sbjct: 2077 SQ---NEHFRLEVKDRGDDGKIPVLYLHKPLDKETARSHTLVLTAADGGKPARSGTMTIK 2133

Query: 569  ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDRE 626
            I+V+DVNDN PVF ++ Y A + E++ +GT+V QV ATD D GLNG + Y    +   R 
Sbjct: 2134 ITVLDVNDNMPVFAKESYVAVLRENSPIGTTVLQVNATDLDDGLNGEVVYSFGNNVNHRL 2193

Query: 627  EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686
               F ID  +G I     +D E    +++   A D G+ P  +   V I I D+ND+ P 
Sbjct: 2194 RKLFEIDADTGEIIVKGQIDYEMKDRYEIDIKASDKGSAPLETEKSVKITILDLNDNAPE 2253

Query: 687  FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746
             E    +  + E+S  GTT+  I   D D G N  V   I   ++   F L     ++  
Sbjct: 2254 IEVTSFSKAVPEDSKPGTTVALISVSDKDSGVNGKVICFI---NEDVPFMLSPTLQANMY 2310

Query: 747  ELVTMVDLDYESPRKKYELVIR---AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN 803
             +VT   LD E    KY++ I    A   PL +   + + V+DVNDN+P        F  
Sbjct: 2311 SVVTKSVLDREH-ESKYDITITAKDAGDQPLSSHRTISVSVSDVNDNSPEFVTNPYTFYV 2369

Query: 804  YKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNN-----ANLILLNETTGSMTLSPQLN 856
             ++  P      V A D D  D   + Y I+   N      + + +N   G ++     +
Sbjct: 2370 TENNDPGTTLFSVSAQDCDERDNSLISYNIIRNGNQHQAITSFLNINSENGQISALKSFD 2429

Query: 857  TNVPKLATMEVSVTD 871
                K+   +V  +D
Sbjct: 2430 FEAQKMFQFQVVASD 2444



 Score =  157 bits (381), Expect = 4e-36
 Identities = 123/443 (27%), Positives = 195/443 (44%), Gaps = 37/443 (8%)

Query: 151  SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII--GGNTQMQ-FSIDSLSG 207
            S   Y   + E+       ++  + ATD D   N+ I +++   G N  +  F ID  SG
Sbjct: 3791 SRSLYKAQIPENTQAGTTVIV--LNATDEDKELNAEIEFSLRSKGQNDVLDLFRIDPKSG 3848

Query: 208  DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
             + +   +DYE+  ++ +  +A D G P  S   ++L+ + DVNDNAP    +    +V 
Sbjct: 3849 AILVNGKIDYEENPAFEIHAQASDKGQPPMSTDCKVLVEVLDVNDNAPEITVTSLLSTVK 3908

Query: 268  ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT---SGQL 324
            E+  +G +I  V   D D G N  +   + +        +P  +D      Y+   +G L
Sbjct: 3909 EDAEVGTAIALVSVLDKDGGKNGIVRAAIAN-------HVPFKLDTNYKNYYSLVVNGAL 3961

Query: 325  DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
            DRE+QA++ + + A D G PP S+T+T              F+     + + E+ P G  
Sbjct: 3962 DRESQAQFNVTIVACDEGAPPLSSTSTVAVQVSDVNDNAPRFLEQAINIYVKENSPVGAT 4021

Query: 385  VVTLTATDADED--NRLHYEITGGNTRGR---FSITSQNGRGLITVAQPLDFKQERRYVL 439
            + T+TA DAD D   ++ Y     N+  +     I   +  G I   Q  D+++ + +  
Sbjct: 4022 MKTITAVDADVDQSGQVRYSYLQSNSESQPLSSMININSETGDIVSLQSFDYEELKTFQF 4081

Query: 440  TVSATDSG--GRSDTAMVQINITDANNYAPVFENAPY-------TASVFEDAPIGTTVLV 490
             V ATDSG    S    V + I D N+  P    APY       + S+   A  G  V  
Sbjct: 4082 QVQATDSGVPPLSSNVSVNVFILDENDNNPAI-LAPYSEHGSVNSESIPYSAEAGYFVAK 4140

Query: 491  VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550
            + A D D G NA ++Y LS    N         F +   TG I T + +    +  + L 
Sbjct: 4141 IRAVDLDSGYNALLSYHLSEPKGNNL-------FRMGTSTGEIRTKRRMSDNDLKSHPLV 4193

Query: 551  VTARDGGVPSLSDTTDVEISVVD 573
            V   D G PSLS T  +E+ VV+
Sbjct: 4194 VLVSDNGEPSLSATVSIEVVVVE 4216



 Score =  154 bits (374), Expect = 3e-35
 Identities = 116/359 (32%), Positives = 168/359 (46%), Gaps = 16/359 (4%)

Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584
           ++ P        +LLDRE +  + L +TA DGG P  S T +V + V+D NDN P+F Q+
Sbjct: 582 LVLPDRRRTNEERLLDREKLREHHLILTAVDGGNPPRSGTLNVTVIVLDSNDNHPIFSQE 641

Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREE-GSFVIDPASGVIRTN 642
           +Y+A++ E+   GTSV +V ATD D G NG I Y     +DR     F ++  +G I+  
Sbjct: 642 VYSADVPENVAAGTSVIKVKATDLDEGANGEIEYFFGGQQDRRTFDIFDLNKETGEIKVK 701

Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
             +D E V    L   A D G PP S+   V IK+ D ND+ P  E   L+  + E+S  
Sbjct: 702 GGIDFEKVEVFKLDVHATDKGQPPMSTDCTVIIKVLDQNDNAPQIEVTSLSNVVPEDSKP 761

Query: 703 GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762
           GT I  I   D D G N  V  S+    D++ F L+     +   LV    LD ES    
Sbjct: 762 GTVISLISITDLDAGLNGKVMCSL---SDNSPFDLKPSFQENMYSLVLKQPLDRESV-SH 817

Query: 763 YELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY 819
           Y++ I A     P L +   + I V+DVNDNAP      I     ++  P      V A 
Sbjct: 818 YDVTITATDCGQPALSDFKTLSIDVSDVNDNAPKYSHSPIELYLVENNAPGSQIFSVTAS 877

Query: 820 DADVTDK--LQYRIL-----SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
           D D+ +   + Y I+      G NA  + +N   G ++     +    K    +V  +D
Sbjct: 878 DKDLNENADISYHIIREEGGQGKNAAFLNINAENGQISALKSFDFETLKTFQFQVVASD 936



 Score =  154 bits (373), Expect = 4e-35
 Identities = 109/354 (30%), Positives = 171/354 (48%), Gaps = 13/354 (3%)

Query: 370 QYEVELAEDEPPGTPVVTLT---ATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
           Q    ++E+   GT V  +      D        Y I G +    F +  ++G  ++ V+
Sbjct: 20  QIRYSISEEVKEGTVVGNIAKDLGIDKASLKEREYRIVGASAEPLFRVNREDG--ILYVS 77

Query: 427 QPLDFKQ--ERRYVLTVSA-TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
           + LD +   E+  V  ++  T      +   V I + D N+++P F        +FE   
Sbjct: 78  KKLDREVICEKSNVCVINLKTVLENPLEIHYVAIEVLDVNDHSPTFPENEKRLEIFESTS 137

Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
            G    +  A D D G      Y LS    N+      ++   + +   +   K LDRE 
Sbjct: 138 TGARFQLQPARDPDGGQFTVQQYRLSP---NDHFRLEVKERGEDRKMPFLILQKALDREA 194

Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
           M  + L +TA DGG P+ S T  + I V+DVNDN PVF +++Y+A++ E++  GT V++V
Sbjct: 195 MKEHKLVLTAVDGGRPAKSGTMGIIIQVLDVNDNSPVFTKEVYSASVNENSPPGTLVTRV 254

Query: 604 GATDADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
            ATD D G NG I Y    +   R +  F IDP +G I+    +D E   ++++   A D
Sbjct: 255 NATDLDEGANGDIIYSFGQEVDTRVKNKFSIDPKTGDIKVTGVIDFEENESYEIDVQASD 314

Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
            GT P S+   V IK++D+ND+PP  E    +  + E+S IGTT+  I A D D
Sbjct: 315 KGTIPLSTYRSVIIKVKDLNDNPPEIEITSFSKSVPEDSRIGTTVALISASDLD 368



 Score =  148 bits (358), Expect = 3e-33
 Identities = 126/483 (26%), Positives = 207/483 (42%), Gaps = 42/483 (8%)

Query: 28   YEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQ 87
            Y+A + E   +GTTV+ L ATD+D   NAE+E+++                       V 
Sbjct: 3795 YKAQIPENTQAGTTVIVLNATDEDKELNAEIEFSLR----------------SKGQNDVL 3838

Query: 88   DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
            D+FRID +SGA+L    +D E+   + +  +A+D+  P    +S+   + V ++D NDN 
Sbjct: 3839 DLFRIDPKSGAILVNGKIDYEENPAFEIHAQASDKGQP---PMSTDCKVLVEVLDVNDNA 3895

Query: 148  PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSID-SLS 206
            P+ +  +   +V ED  V     IA +   D D G N  +R AI      + F +D +  
Sbjct: 3896 PEITVTSLLSTVKEDAEV--GTAIALVSVLDKDGGKNGIVRAAIA---NHVPFKLDTNYK 3950

Query: 207  GDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
               SLV    LD E    + + I A D G+P  S+T+ + + + DVNDNAPRF       
Sbjct: 3951 NYYSLVVNGALDRESQAQFNVTIVACDEGAPPLSSTSTVAVQVSDVNDNAPRFLEQAINI 4010

Query: 265  SVSENVPIGYSIVRVQAYDADEGVNAELTYT-MTDKDYTGNVDLPITIDPRSGWVYTSGQ 323
             V EN P+G ++  + A DAD   + ++ Y+ +     +  +   I I+  +G + +   
Sbjct: 4011 YVKENSPVGATMKTITAVDADVDQSGQVRYSYLQSNSESQPLSSMININSETGDIVSLQS 4070

Query: 324  LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE---- 379
             D E    +Q  V ATD G PP S+  +               +    E      E    
Sbjct: 4071 FDYEELKTFQFQVQATDSGVPPLSSNVSVNVFILDENDNNPAILAPYSEHGSVNSESIPY 4130

Query: 380  --PPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435
                G  V  + A D D   +  L Y ++       F + +  G   I   + +     +
Sbjct: 4131 SAEAGYFVAKIRAVDLDSGYNALLSYHLSEPKGNNLFRMGTSTGE--IRTKRRMSDNDLK 4188

Query: 436  RYVLTVSATDSGGRSDTAMVQINI----TDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491
             + L V  +D+G  S +A V I +    + A+   P   N P     F D  +   + +V
Sbjct: 4189 SHPLVVLVSDNGEPSLSATVSIEVVVVESGADIQTPFRHNVPMKEESFSDLNLYLLIAIV 4248

Query: 492  SAT 494
            + +
Sbjct: 4249 AVS 4251



 Score =  127 bits (306), Expect = 5e-27
 Identities = 85/292 (29%), Positives = 140/292 (47%), Gaps = 24/292 (8%)

Query: 4   PFCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
           P  IH   I VLD NDHSP F   +    + E  S+G       A D D G+    +Y  
Sbjct: 103 PLEIHYVAIEVLDVNDHSPTFPENEKRLEIFESTSTGARFQLQPARDPDGGQFTVQQYR- 161

Query: 63  ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122
                  L+P D                  D +   L+ + +LDRE +  + +++ A D 
Sbjct: 162 -------LSPNDHFRLEVKERGE-------DRKMPFLILQKALDREAMKEHKLVLTAVDG 207

Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
             P     S T  I + ++D NDN P F+++ Y+ SV+E+       ++ ++ ATD D G
Sbjct: 208 GRPAK---SGTMGIIIQVLDVNDNSPVFTKEVYSASVNENSP--PGTLVTRVNATDLDEG 262

Query: 183 ANSAIRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239
           AN  I Y+    +    + +FSID  +GD+ +   +D+E+  SY + ++A D G+   S 
Sbjct: 263 ANGDIIYSFGQEVDTRVKNKFSIDPKTGDIKVTGVIDFEENESYEIDVQASDKGTIPLST 322

Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE 291
              ++I ++D+NDN P    + F +SV E+  IG ++  + A D D  V ++
Sbjct: 323 YRSVIIKVKDLNDNPPEIEITSFSKSVPEDSRIGTTVALISASDLDSVVASD 374



 Score =  122 bits (295), Expect = 1e-25
 Identities = 84/313 (26%), Positives = 141/313 (45%), Gaps = 11/313 (3%)

Query: 87  QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146
           + +FR++   G L     LDRE +   + +         V +       + + ++D ND+
Sbjct: 62  EPLFRVNREDGILYVSKKLDREVICEKSNV--CVINLKTVLENPLEIHYVAIEVLDVNDH 119

Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206
            P F E    + + E  S      +    A D D G  +  +Y +   N   +  +    
Sbjct: 120 SPTFPENEKRLEIFESTSTGARFQLQP--ARDPDGGQFTVQQYRL-SPNDHFRLEVKERG 176

Query: 207 GD-----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261
            D     + L K LD E ++ ++LV+ A DGG P++S T  ++I + DVNDN+P F   +
Sbjct: 177 EDRKMPFLILQKALDREAMKEHKLVLTAVDGGRPAKSGTMGIIIQVLDVNDNSPVFTKEV 236

Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321
           +  SV+EN P G  + RV A D DEG N ++ Y+   ++    V    +IDP++G +  +
Sbjct: 237 YSASVNENSPPGTLVTRVNATDLDEGANGDIIYSF-GQEVDTRVKNKFSIDPKTGDIKVT 295

Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381
           G +D E    Y++ V A+D G  P S   +                   +   + ED   
Sbjct: 296 GVIDFEENESYEIDVQASDKGTIPLSTYRSVIIKVKDLNDNPPEIEITSFSKSVPEDSRI 355

Query: 382 GTPVVTLTATDAD 394
           GT V  ++A+D D
Sbjct: 356 GTTVALISASDLD 368



 Score =  120 bits (290), Expect = 4e-25
 Identities = 103/326 (31%), Positives = 150/326 (46%), Gaps = 21/326 (6%)

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
           S+ E+   GT   VV     D+GI+     SL         A  +  F +N + G +  +
Sbjct: 24  SISEEVKEGT---VVGNIAKDLGIDKA---SLKEREYRIVGASAEPLFRVNREDGILYVS 77

Query: 537 KLLDRETMSGYL-LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
           K LDRE +     + V      + +  +   V I V+DVND+ P F +      I E   
Sbjct: 78  KKLDREVICEKSNVCVINLKTVLENPLEIHYVAIEVLDVNDHSPTFPENEKRLEIFESTS 137

Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDR---EEGSFVIDPASGVIRTNKALDRESVAT 652
            G       A D D G      Y L P D    E      D     +   KALDRE++  
Sbjct: 138 TGARFQLQPARDPDGGQFTVQQYRLSPNDHFRLEVKERGEDRKMPFLILQKALDREAMKE 197

Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
           H L   A+DGG P +S T+ + I++ D+ND+ PVF  +  +  ++ENSP GT +  + A 
Sbjct: 198 HKLVLTAVDGGRPAKSGTMGIIIQVLDVNDNSPVFTKEVYSASVNENSPPGTLVTRVNAT 257

Query: 713 DPDEGPNAVVHYSIKGGDDS---NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
           D DEG N  + YS     D+   N FS++ + G  K   VT V +D+E   + YE+ ++A
Sbjct: 258 DLDEGANGDIIYSFGQEVDTRVKNKFSIDPKTGDIK---VTGV-IDFEE-NESYEIDVQA 312

Query: 770 ASP---PLWNDVRVEILVTDVNDNAP 792
           +     PL     V I V D+NDN P
Sbjct: 313 SDKGTIPLSTYRSVIIKVKDLNDNPP 338



 Score = 88.6 bits (210), Expect = 2e-15
 Identities = 73/279 (26%), Positives = 130/279 (46%), Gaps = 25/279 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V D ND++P F  Q     V+E +  G T+ T+ A D D+ ++ +V Y+  L +    
Sbjct: 3991 VQVSDVNDNAPRFLEQAINIYVKENSPVGATMKTITAVDADVDQSGQVRYSY-LQSNSES 4049

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             P             +  +  I+  +G +++  S D E++  +   V+ATD   P    L
Sbjct: 4050 QP-------------LSSMININSETGDIVSLQSFDYEELKTFQFQVQATDSGVPP---L 4093

Query: 131  SSTATIHVNIIDDNDNYP----QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
            SS  +++V I+D+NDN P     +SE     S     S      +AKI+A D D G N+ 
Sbjct: 4094 SSNVSVNVFILDENDNNPAILAPYSEHGSVNSESIPYSAEAGYFVAKIRAVDLDSGYNAL 4153

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            + Y +        F + + +G++   + +    ++S+ LV+   D G PS S T  + + 
Sbjct: 4154 LSYHLSEPKGNNLFRMGTSTGEIRTKRRMSDNDLKSHPLVVLVSDNGEPSLSATVSIEVV 4213

Query: 247  IRD--VNDNAP-RFYTSLFQESVSE-NVPIGYSIVRVQA 281
            + +   +   P R    + +ES S+ N+ +  +IV V A
Sbjct: 4214 VVESGADIQTPFRHNVPMKEESFSDLNLYLLIAIVAVSA 4252



 Score = 72.1 bits (169), Expect = 2e-10
 Identities = 73/275 (26%), Positives = 119/275 (43%), Gaps = 37/275 (13%)

Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT-------ANIMEDALVGTSVSQ 602
           +V A D G PSLS    V++ ++D NDN PV    + +         I  +   G  V++
Sbjct: 369 SVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTK 428

Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
           V A DAD+G NG + + L  +  +   F +D  +G IRT ++      A H L  +  D 
Sbjct: 429 VRAYDADIGYNGWLLFALQ-EVSDHSLFGLDRYTGQIRTLRSFTETDEAEHKLVILVKDN 487

Query: 663 GTPPQSSTVIVHIKI---------EDINDSPPVFESDCLTFYISEN----------SPIG 703
           G    S+T  V +K+          D+  S    E   +TFY+             S I 
Sbjct: 488 GNVSLSATATVLVKLVEPKEAFAASDVQSSAQDDEDSHVTFYLMITLGSVSVLFVISIIV 547

Query: 704 TTIGEIRAHDPD---EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760
               + R+ D      GP   +  +I  G  +N+  L  R+ +++  L     LD E  R
Sbjct: 548 LIAMQYRSGDKRYMLVGPRMSIGSTIVPGSHANTLVLPDRRRTNEERL-----LDREKLR 602

Query: 761 KKYELV--IRAASPPLWNDVRVEILVTDVNDNAPV 793
           + + ++  +   +PP    + V ++V D NDN P+
Sbjct: 603 EHHLILTAVDGGNPPRSGTLNVTVIVLDSNDNHPI 637



 Score = 57.2 bits (132), Expect = 6e-06
 Identities = 60/205 (29%), Positives = 92/205 (44%), Gaps = 15/205 (7%)

Query: 627 EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE--DINDSP 684
           E  F ++   G++  +K LDRE +       V I+  T  ++   I ++ IE  D+ND  
Sbjct: 62  EPLFRVNREDGILYVSKKLDREVICEKSNVCV-INLKTVLENPLEIHYVAIEVLDVNDHS 120

Query: 685 PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ-GS 743
           P F  +     I E++  G       A DPD G   V  Y +   D    F LE ++ G 
Sbjct: 121 PTFPENEKRLEIFESTSTGARFQLQPARDPDGGQFTVQQYRLSPNDH---FRLEVKERGE 177

Query: 744 DKAE--LVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQ 798
           D+    L+    LD E+  K+++LV+ A     P     + + I V DVNDN+PV    +
Sbjct: 178 DRKMPFLILQKALDREA-MKEHKLVLTAVDGGRPAKSGTMGIIIQVLDVNDNSPVFTK-E 235

Query: 799 IIFNNYKDCFPVGPF-GRVPAYDAD 822
           +   +  +  P G    RV A D D
Sbjct: 236 VYSASVNENSPPGTLVTRVNATDLD 260



 Score = 39.1 bits (87), Expect = 1.7
 Identities = 31/101 (30%), Positives = 50/101 (49%), Gaps = 8/101 (7%)

Query: 650 VATHDLKAV-AIDGGTPPQSSTVIVHIKIEDINDSPPVF----ESDCLTFYISE---NSP 701
           ++  DL +V A D G+P  SS V V + I D ND+ PV      S+     + E   N  
Sbjct: 362 ISASDLDSVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVN 421

Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
            G  + ++RA+D D G N  + ++++   D + F L+   G
Sbjct: 422 AGHLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTG 462


>UniRef50_Q9BZA7 Cluster: Protocadherin-11 X-linked precursor;
           n=115; Euteleostomi|Rep: Protocadherin-11 X-linked
           precursor - Homo sapiens (Human)
          Length = 1347

 Score =  281 bits (688), Expect = 3e-73
 Identities = 210/677 (31%), Positives = 325/677 (48%), Gaps = 40/677 (5%)

Query: 89  VFRIDGRSGALLTR-ASLDREKVARYTVLVKATDQASPVS---DRLSSTATIHVNIIDDN 144
           + RI+  +G + T  A +DREK+       +       V+   D +     I   I D N
Sbjct: 74  LIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDIN 133

Query: 145 DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS 204
           DN P F      +S+ E+ ++     +    A D DVG N    Y +I   +Q  F +D 
Sbjct: 134 DNAPLFPATVINISIPENSAINSKYTLPA--AVDPDVGINGVQNYELI--KSQNIFGLDV 189

Query: 205 LS---GD----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF 257
           +    GD    + + K LD E+  +Y + ++ +DGG P RS+T  L +++ D NDN P F
Sbjct: 190 IETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVF 249

Query: 258 YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI-TIDPRSG 316
             +  + S+ EN P+G S+ ++ A DAD G NA++ ++ +  +   N+   +  ++  +G
Sbjct: 250 KETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFS--NLVSNIARRLFHLNATTG 307

Query: 317 WVYTSGQLDRETQAKYQLLVTATDGGDPPRSA----TATXXXXXXXXXXXXXXFMPGQYE 372
            +     LDRE    ++LLV A+DGG  P  A      T                P    
Sbjct: 308 LITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDT 367

Query: 373 VELAEDEPPGTPVVTLTATDADEDNRLHYE-ITGGNTRGRFSITSQNGRGLITVAQPLDF 431
           V L+E+ P  T +  +T TD D D+       T      R      N + L+  A  LD+
Sbjct: 368 VVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSN-QFLLETAAYLDY 426

Query: 432 KQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
           +  + Y + + A D+G    + +AM+ I + D N+ APVF  +  T S+ E+   G  + 
Sbjct: 427 ESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLT 486

Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
            VSA D+D G NA+I Y L  +   E        F ++ +TG +T  K LDRE    YL 
Sbjct: 487 KVSAMDADSGPNAKINYLLGPDAPPE--------FSLDCRTGMLTVVKKLDREKEDKYLF 538

Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
           T+ A+D GVP L+    V +S++D NDN PVF    Y   + E+     +V  +  TD D
Sbjct: 539 TILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPD 598

Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669
            G N  +   L   D E   F ID  +GVIR N + DRE   ++     A DGG   +SS
Sbjct: 599 YGDNSAV--TLSILD-ENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSS 655

Query: 670 TVIVHIKIEDINDSPPVF---ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
           +  V I + D+ND+ PVF    S+C    +  ++  GT + ++ A D D G NA V YSI
Sbjct: 656 SAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSI 715

Query: 727 KGGDDSNSFSLETRQGS 743
            GG+  + F+++   G+
Sbjct: 716 VGGNTRDLFAIDQETGN 732



 Score =  262 bits (642), Expect = 1e-67
 Identities = 204/689 (29%), Positives = 319/689 (46%), Gaps = 46/689 (6%)

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
           I D+NDNAP F  ++   S+ EN  I        A D D G+N    Y +        +D
Sbjct: 129 IEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLD 188

Query: 307 LPITID-PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
           +  T +  +   +    +LDRE +  Y + V   DGG P RS+TA               
Sbjct: 189 VIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPV 248

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYE---ITGGNTRGRFSITSQNGR 420
           F   + EV + E+ P GT V  L ATDAD  E+ ++H+    +     R  F + +  G 
Sbjct: 249 FKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG- 307

Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAP------VFENAPY 474
            LIT+ +PLD ++   + L V A+D G     AMV +N+TD N+  P      +      
Sbjct: 308 -LITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVND 366

Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
           T  + E+ P+ T + +++ TD D   N ++T     EI          QF++        
Sbjct: 367 TVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLE------- 419

Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
           T   LD E+   Y + + A D G P L+ +  + I V D NDN PVF Q   T +I E+ 
Sbjct: 420 TAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENN 479

Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654
             G  +++V A DAD G N +I+Y L P    E  F +D  +G++   K LDRE    + 
Sbjct: 480 SPGIQLTKVSAMDADSGPNAKINYLLGPDAPPE--FSLDCRTGMLTVVKKLDREKEDKYL 537

Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
              +A D G PP +S V V + I D ND+ PVF  +   FY+ EN P   T+G I   DP
Sbjct: 538 FTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDP 597

Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---AS 771
           D G N+ V  SI   D+++ F+++++ G  +      +  D E  ++ Y   ++A     
Sbjct: 598 DYGDNSAVTLSIL--DENDDFTIDSQTGVIRPN----ISFDREK-QESYTFYVKAEDGGR 650

Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN--YKDCFPVGPFG----RVPAYDAD--V 823
               +  +V I V DVNDN PV   F +  +N  Y+   P    G    +V A D D  +
Sbjct: 651 VSRSSSAKVTINVVDVNDNKPV---FIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGM 707

Query: 824 TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLS 883
             +++Y I+ GN  +L  +++ TG++TL  + +     L  + V   D          + 
Sbjct: 708 NAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVI 767

Query: 884 VRLITEEMLLNSITVRLNDMTAEQFLSPL 912
           V L   E + N+  +  N++  +   +P+
Sbjct: 768 VNLFVNESVTNATLI--NELVRKSTEAPV 794



 Score =  215 bits (524), Expect = 2e-53
 Identities = 170/613 (27%), Positives = 278/613 (45%), Gaps = 52/613 (8%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           Q++V D ND+ PVF+  + E S+ E A  GT+V  L ATD DIG+NA++ ++   + ++ 
Sbjct: 236 QVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSN- 294

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                            + +F ++  +G +  +  LDRE+   + +LV A+D        
Sbjct: 295 ---------------IARRLFHLNATTGLITIKEPLDREETPNHKLLVLASD-----GGL 334

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDN-PV---IAKIKATDADVGANS 185
           + + A + VN+ D NDN P    +     V++ + +++N P+   IA I  TD D   N 
Sbjct: 335 MPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNG 394

Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
            +       + ++ F +  +  +  L++T   LDYE  + Y + + A D G P  + +  
Sbjct: 395 RVTCFT---DHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAM 451

Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
           L I ++D NDNAP F  S    S+ EN   G  + +V A DAD G NA++ Y +      
Sbjct: 452 LFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGP---- 507

Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
            +     ++D R+G +    +LDRE + KY   + A D G PP ++  T           
Sbjct: 508 -DAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDN 566

Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422
              F   +Y   + E+ P    V  +T TD D  +     ++  +    F+I SQ   G+
Sbjct: 567 SPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQT--GV 624

Query: 423 ITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS--- 477
           I      D +++  Y   V A D G   RS +A V IN+ D N+  PVF   P   S   
Sbjct: 625 IRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYEL 684

Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
           V      GT V  V A D+D G+NA++ YS+    + +        F I+ +TG IT  +
Sbjct: 685 VLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDL-------FAIDQETGNITLME 737

Query: 538 LLDRETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
             D   +  + + V A D G P SL     V + V +   N  +   +L   +       
Sbjct: 738 KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI-NELVRKSTEAPVTP 796

Query: 597 GTSVSQVGATDAD 609
            T ++ V +  +D
Sbjct: 797 NTEIADVSSPTSD 809



 Score =  168 bits (409), Expect = 2e-39
 Identities = 134/415 (32%), Positives = 198/415 (47%), Gaps = 23/415 (5%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           ++  I D N+ AP+F       S+ E++ I +   + +A D DVGIN    Y L   I +
Sbjct: 125 IRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYEL---IKS 181

Query: 515 EAVAHHDQ-QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
           + +   D  +     +   +   K LDRE    Y++ V   DGG P  S T  +++SV D
Sbjct: 182 QNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTD 241

Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD--PKDREEGSFV 631
            NDN PVFK+     +I E+A VGTSV+Q+ ATDAD+G N +IH+       +     F 
Sbjct: 242 TNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFH 301

Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691
           ++  +G+I   + LDRE    H L  +A DGG  P  + V+V+  + D+ND+ P  +   
Sbjct: 302 LNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVN--VTDVNDNVPSIDIRY 359

Query: 692 L------TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745
           +      T  +SEN P+ T I  I   D D   N  V       D    F L     S++
Sbjct: 360 IVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFT---DHEIPFRLRP-VFSNQ 415

Query: 746 AELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN 802
             L T   LDYES  K+Y + + AA    PPL     + I V D NDNAPV     +  +
Sbjct: 416 FLLETAAYLDYES-TKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVS 474

Query: 803 NYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNA-NLILLNETTGSMTLSPQLN 856
             ++  P     +V A DAD     +   L G +A     L+  TG +T+  +L+
Sbjct: 475 IPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLD 529


>UniRef50_Q4S3N9 Cluster: Chromosome 17 SCAF14747, whole genome
            shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
            Chromosome 17 SCAF14747, whole genome shotgun sequence -
            Tetraodon nigroviridis (Green puffer)
          Length = 1526

 Score =  280 bits (687), Expect = 3e-73
 Identities = 220/665 (33%), Positives = 331/665 (49%), Gaps = 59/665 (8%)

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +ST+T+ V ++D ND  P F  + Y VS+ E  S+  + V+A++  +D D G N+ + Y 
Sbjct: 819  TSTSTLTVKVLDVNDETPTFDPRVYNVSLKE--SIPRDHVVARLACSDNDAGLNAELSYF 876

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG--SPSRSNTTQLLINIR 248
            I GGN   +FS+    G V  V  LD E   +Y L++ A D G     R+ T  + + ++
Sbjct: 877  ITGGNQDGKFSVGFRDGIVRTVVGLDRETQAAYTLIVEAIDNGPAGSRRTGTATVFVEVQ 936

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            DVNDN P F  + ++ SV E+VP G SI++VQA DAD+G N  + Y +     TGN +  
Sbjct: 937  DVNDNRPIFLQNSYETSVLESVPQGTSILQVQATDADQGENGSVLYRI----LTGNSNNL 992

Query: 309  ITIDPRSGWVYTSG--QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
             +ID ++G V T G   LDRET + + L V A +  +    ++                F
Sbjct: 993  FSIDRQTGLV-TRGLRALDRETSSSHMLEVEAYNSDEGSMRSSVRVIIYVNDANDEVPVF 1051

Query: 367  MPGQY-EVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLI 423
               QY  + L E    GT V+ + ATD D  +   + Y +  G+ R +F +      GL+
Sbjct: 1052 TQQQYNRLGLRETAGVGTSVIVVRATDPDTGDGGAVAYALVSGSDR-KFEVDVST--GLV 1108

Query: 424  TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
            T    LD++ +    +T+               +N  D    A  F +A Y AS+ E+  
Sbjct: 1109 TTVDYLDYETKTTVYVTL---------------LNELDE---AVAFSSAGYEASLRENIA 1150

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
             GT V+ V A  +D  +N Q+TY    + S  A+A     F I+  TG IT   LLDRE 
Sbjct: 1151 TGTEVIQVQAQSAD-NLN-QLTYRFDPDTSPAALA----LFKIDSVTGRITVTGLLDRER 1204

Query: 544  MSGYLLTVTARDGG-------VPSLSDTTDVEISVVDVNDNEPVFKQQLYTA-NIMEDAL 595
               Y LTV A DGG       + S S +  V I+++D NDN PVF     T+ +I E+  
Sbjct: 1205 GDAYTLTVVADDGGPKKDSTVITSDSISQQVSITILDENDNSPVFDITSDTSVDITENTP 1264

Query: 596  VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV--IDPASGVIRTNKALDRESVATH 653
            +G  V+ V A D D GLNG I++ L   + ++   +  ++   G +  N  LDRESV  +
Sbjct: 1265 MGEKVAVVLARDKDAGLNGLINFTLVAGNMKDVFKIKTVNHTYGEVYVNAPLDRESVDRY 1324

Query: 654  DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD-CLTFYISENSPIGTTIGEIRAH 712
             LK  A D G+PP+ +   + I I D+ND+ PV ES       ISEN   GT++  + A 
Sbjct: 1325 LLKVRATDNGSPPRHTDHSLTINILDVNDNAPVIESQKGYNVSISENVGGGTSVLRVMAT 1384

Query: 713  DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA--- 769
            D D GPNA++ Y I  G+   +F ++   G    E+VT         +++Y L +     
Sbjct: 1385 DRDIGPNAMLFYYITAGNQDLTFRMDRMTG----EMVTRPAPPDRERQQEYILTVTVEDD 1440

Query: 770  ASPPL 774
             +PPL
Sbjct: 1441 GTPPL 1445



 Score =  267 bits (654), Expect = 3e-69
 Identities = 219/675 (32%), Positives = 318/675 (47%), Gaps = 71/675 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + VLD ND +P F+ + Y  S++E       V  L  +D D G NAE+ Y I      T 
Sbjct: 826  VKVLDVNDETPTFDPRVYNVSLKESIPRDHVVARLACSDNDAGLNAELSYFI------TG 879

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
              +D               F +  R G + T   LDRE  A YT++V+A D   P   R 
Sbjct: 880  GNQDGK-------------FSVGFRDGIVRTVVGLDRETQAAYTLIVEAIDNG-PAGSRR 925

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            + TAT+ V + D NDN P F + +Y  SV E  SV     I +++ATDAD G N ++ Y 
Sbjct: 926  TGTATVFVEVQDVNDNRPIFLQNSYETSVLE--SVPQGTSILQVQATDADQGENGSVLYR 983

Query: 191  IIGGNTQMQFSIDSLSGDVSL-VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            I+ GN+   FSID  +G V+  ++ LD E   S+ L + A +    S  ++ +++I + D
Sbjct: 984  ILTGNSNNLFSIDRQTGLVTRGLRALDRETSSSHMLEVEAYNSDEGSMRSSVRVIIYVND 1043

Query: 250  VNDNAPRFYTSLFQE-SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
             ND  P F    +    + E   +G S++ V+A D D G    + Y +     +G+ D  
Sbjct: 1044 ANDEVPVFTQQQYNRLGLRETAGVGTSVIVVRATDPDTGDGGAVAYALV----SGS-DRK 1098

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
              +D  +G V T   LD ET  K  + VT  +  D    A A               F  
Sbjct: 1099 FEVDVSTGLVTTVDYLDYET--KTTVYVTLLNELD---EAVA---------------FSS 1138

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEI---TGGNTRGRFSITSQNGRGLITV 425
              YE  L E+   GT V+ + A  AD  N+L Y     T       F I S  GR  ITV
Sbjct: 1139 AGYEASLRENIATGTEVIQVQAQSADNLNQLTYRFDPDTSPAALALFKIDSVTGR--ITV 1196

Query: 426  AQPLDFKQERRYVLTVSATDSGGRSDTAMV-------QINIT--DANNYAPVFENAPYTA 476
               LD ++   Y LTV A D G + D+ ++       Q++IT  D N+ +PVF+    T+
Sbjct: 1197 TGLLDRERGDAYTLTVVADDGGPKKDSTVITSDSISQQVSITILDENDNSPVFDITSDTS 1256

Query: 477  -SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
              + E+ P+G  V VV A D D G+N  I ++L +    +          +N   G +  
Sbjct: 1257 VDITENTPMGEKVAVVLARDKDAGLNGLINFTLVAGNMKDVFKIK----TVNHTYGEVYV 1312

Query: 536  NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL-YTANIMEDA 594
            N  LDRE++  YLL V A D G P       + I+++DVNDN PV + Q  Y  +I E+ 
Sbjct: 1313 NAPLDRESVDRYLLKVRATDNGSPPRHTDHSLTINILDVNDNAPVIESQKGYNVSISENV 1372

Query: 595  LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA-LDRESVATH 653
              GTSV +V ATD D+G N  + Y +     ++ +F +D  +G + T  A  DRE    +
Sbjct: 1373 GGGTSVLRVMATDRDIGPNAMLFYYI-TAGNQDLTFRMDRMTGEMVTRPAPPDRERQQEY 1431

Query: 654  DLKAVAIDGGTPPQS 668
             L     D GTPP S
Sbjct: 1432 ILTVTVEDDGTPPLS 1446



 Score =  263 bits (644), Expect = 6e-68
 Identities = 218/661 (32%), Positives = 315/661 (47%), Gaps = 64/661 (9%)

Query: 218  EQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277
            EQ+  Y L I A D G+  R++T+ L + + DVND  P F   ++  S+ E++P  + + 
Sbjct: 799  EQIGLYYLRIIAYDAGNFPRTSTSTLTVKVLDVNDETPTFDPRVYNVSLKESIPRDHVVA 858

Query: 278  RVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVT 337
            R+   D D G+NAEL+Y +T     GN D   ++  R G V T   LDRETQA Y L+V 
Sbjct: 859  RLACSDNDAGLNAELSYFITG----GNQDGKFSVGFRDGIVRTVVGLDRETQAAYTLIVE 914

Query: 338  ATDGG--DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD- 394
            A D G     R+ TAT              F+   YE  + E  P GT ++ + ATDAD 
Sbjct: 915  AIDNGPAGSRRTGTATVFVEVQDVNDNRPIFLQNSYETSVLESVPQGTSILQVQATDADQ 974

Query: 395  -EDNRLHYEITGGNTRGRFSITSQNGRGLITVA-QPLDFKQERRYVLTVSA--TDSGGRS 450
             E+  + Y I  GN+   FSI  Q   GL+T   + LD +    ++L V A  +D G   
Sbjct: 975  GENGSVLYRILTGNSNNLFSIDRQT--GLVTRGLRALDRETSSSHMLEVEAYNSDEGSMR 1032

Query: 451  DTAMVQINITDANNYAPVFENAPYT-ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509
             +  V I + DAN+  PVF    Y    + E A +GT+V+VV ATD D G    + Y+L 
Sbjct: 1033 SSVRVIIYVNDANDEVPVFTQQQYNRLGLRETAGVGTSVIVVRATDPDTGDGGAVAYAL- 1091

Query: 510  SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569
                   V+  D++F ++  TG +TT   LD ET                     T V +
Sbjct: 1092 -------VSGSDRKFEVDVSTGLVTTVDYLDYET--------------------KTTVYV 1124

Query: 570  SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE-- 627
            ++++  D    F    Y A++ E+   GT V QV A  AD  LN ++ Y  DP       
Sbjct: 1125 TLLNELDEAVAFSSAGYEASLRENIATGTEVIQVQAQSAD-NLN-QLTYRFDPDTSPAAL 1182

Query: 628  GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI--------VHIKIED 679
              F ID  +G I     LDRE    + L  VA DGG P + STVI        V I I D
Sbjct: 1183 ALFKIDSVTGRITVTGLLDRERGDAYTLTVVADDGG-PKKDSTVITSDSISQQVSITILD 1241

Query: 680  INDSPPVFE-SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738
             ND+ PVF+ +   +  I+EN+P+G  +  + A D D G N ++++++  G+  + F ++
Sbjct: 1242 ENDNSPVFDITSDTSVDITENTPMGEKVAVVLARDKDAGLNGLINFTLVAGNMKDVFKIK 1301

Query: 739  TRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMK 795
            T       E+     LD ES   +Y L +RA    SPP   D  + I + DVNDNAPV++
Sbjct: 1302 T-VNHTYGEVYVNAPLDRESV-DRYLLKVRATDNGSPPRHTDHSLTINILDVNDNAPVIE 1359

Query: 796  DFQIIFNNYKDCFPVG-PFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLS 852
              +    +  +    G    RV A D D+     L Y I +GN      ++  TG M   
Sbjct: 1360 SQKGYNVSISENVGGGTSVLRVMATDRDIGPNAMLFYYITAGNQDLTFRMDRMTGEMVTR 1419

Query: 853  P 853
            P
Sbjct: 1420 P 1420



 Score =  258 bits (633), Expect = 1e-66
 Identities = 216/742 (29%), Positives = 337/742 (45%), Gaps = 54/742 (7%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F IDG  G +     LD E  + Y + V ATDQ       LS  A + ++I D  D  P 
Sbjct: 38  FAIDGARGTVTVTKPLDYETTSAYQLTVNATDQDK--LRPLSRLANLAISITDVQDMDPI 95

Query: 150 FSEKTYTVSVDEDISVTDN------PV--------IAKIKATDADVGANSAIRYAIIGGN 195
           F+   Y+ +++ED+ +         P+        + KI A D D+G    I Y I+ GN
Sbjct: 96  FTNLPYSTNIEEDVPLISQTQTHLGPLHTALQGYEVRKITAMDQDLGRPRGIGYTIVSGN 155

Query: 196 TQMQFSIDSLSGDVSLVKTLDYEQV---RSYRLVIRA---QDGGSPSRSNT-TQLLINIR 248
           T   F++D +SG +++   LD E       + L ++A   ++   PS +   T   I + 
Sbjct: 156 TNSVFALDYISGSLTVSGQLDRENPLYSAGFTLTVKATELKEDRFPSDATVMTTFTILLI 215

Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSI-VRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
           D NDNAP+F +S ++  ++E   +G+++ + +QA D DEGVN+     +T  +       
Sbjct: 216 DKNDNAPKFNSSEYRLQITELAQVGFALPLFIQAEDKDEGVNSMFQVFLTGNNSEYFTLS 275

Query: 308 PITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
           P  +  R+   +  +  LD E    Y   + A +         A               F
Sbjct: 276 PTAVQGRADIRMRVAMPLDYEHIRSYSFSLYANESMSD-HVGFARVFIELINENDNRPIF 334

Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
               Y + L E+  PGT ++ + ATDAD            +   +FS+  + G  ++  +
Sbjct: 335 SKPLYNISLPENTAPGTSLLRILATDADAGTFGIVRYYFSDDPDQFSLDEETGWVILQAS 394

Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
             LD++  RR+ LTV A D GG   T  +++N+ D N+ AP+F+   Y  S+ E+     
Sbjct: 395 --LDYELMRRFTLTVLARDGGGEETTGRIRVNVLDVNDNAPLFQKEAYVGSLRENEQAVQ 452

Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
            V  + ATD D   N  +TY++   IS  A   +    ++        T  L   +  SG
Sbjct: 453 PVARLRATDEDSPPNNFLTYTI---ISASAFPSYFSIIMVEGYAVISVTRPLDYEQVPSG 509

Query: 547 YL-LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG--TSVSQV 603
            + L V  +DGG P+L+ T  V + V+D NDN P F +  Y   I E+   G   +V  V
Sbjct: 510 MIHLEVMVKDGGSPALNSTVPVTVEVIDENDNPPEFSKSSYIVKIPENINAGEWATVLLV 569

Query: 604 GATDADVGL---NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
            ATD D         + Y L+   +    F ++  SG I T   LDRE  + + L   A+
Sbjct: 570 NATDLDASREFGQASLIYSLEGSSQ----FRLNSRSGEITTTALLDRELKSEYILIVRAV 625

Query: 661 DGGTPPQSSTVI--VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
           DGG  PQ  T I  V+I I DIND+ PV+  +     + E SPI T +  + A DPD G 
Sbjct: 626 DGGVGPQQKTGIATVNITILDINDNAPVWRDEPYHANVVEMSPINTDVISVLALDPDNGE 685

Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY---ELVIRA---ASP 772
           N  V YSI    ++  +++ +  G  +   VT+ D +  +PR       ++I A    SP
Sbjct: 686 NGTVVYSI--SPENPFYTINSSTGKIRTSGVTL-DRESSNPRDAILMRTIIISAVDRGSP 742

Query: 773 PLWNDVRVEILVT--DVNDNAP 792
            L       + V   D+NDN P
Sbjct: 743 QLRASASTTVFVNLLDLNDNDP 764



 Score =  254 bits (623), Expect = 2e-65
 Identities = 223/734 (30%), Positives = 332/734 (45%), Gaps = 70/734 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGK--NAEVEYTIELVTA- 67
           I++ D  D  P+F    Y  ++ E       V  +  T   +G    A   Y +  +TA 
Sbjct: 84  ISITDVQDMDPIFTNLPYSTNIEED------VPLISQTQTHLGPLHTALQGYEVRKITAM 137

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKV---ARYTVLVKATDQAS 124
           D                    VF +D  SG+L     LDRE     A +T+ VKAT+   
Sbjct: 138 DQDLGRPRGIGYTIVSGNTNSVFALDYISGSLTVSGQLDRENPLYSAGFTLTVKATELKE 197

Query: 125 PVSDRLSSTATIHVN----IIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD 180
              DR  S AT+       +ID NDN P+F+   Y + + E ++     +   I+A D D
Sbjct: 198 ---DRFPSDATVMTTFTILLIDKNDNAPKFNSSEYRLQITE-LAQVGFALPLFIQAEDKD 253

Query: 181 VGANSAIRYAIIGGNTQ-MQFSIDSLSG--DVSL--VKTLDYEQVRSYRLVIRAQDGGSP 235
            G NS  +  + G N++    S  ++ G  D+ +     LDYE +RSY   + A +  S 
Sbjct: 254 EGVNSMFQVFLTGNNSEYFTLSPTAVQGRADIRMRVAMPLDYEHIRSYSFSLYANESMS- 312

Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295
                 ++ I + + NDN P F   L+  S+ EN   G S++R+ A DAD G    + Y 
Sbjct: 313 DHVGFARVFIELINENDNRPIFSKPLYNISLPENTAPGTSLLRILATDADAGTFGIVRYY 372

Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355
            +D     + D   ++D  +GWV     LD E   ++ L V A DGG      T      
Sbjct: 373 FSD-----DPD-QFSLDEETGWVILQASLDYELMRRFTLTVLARDGGG--EETTGRIRVN 424

Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNT-RGRF 412
                     F    Y   L E+E    PV  L ATD D   +N L Y I   +     F
Sbjct: 425 VLDVNDNAPLFQKEAYVGSLRENEQAVQPVARLRATDEDSPPNNFLTYTIISASAFPSYF 484

Query: 413 SITSQNGRGLITVAQPLDFKQERRYV--LTVSATDSGGRS--DTAMVQINITDANNYAPV 468
           SI    G  +I+V +PLD++Q    +  L V   D G  +   T  V + + D N+  P 
Sbjct: 485 SIIMVEGYAVISVTRPLDYEQVPSGMIHLEVMVKDGGSPALNSTVPVTVEVIDENDNPPE 544

Query: 469 FENAPYTASVFEDAPIG--TTVLVVSATDSDVGIN---AQITYSLSSEISNEAVAHHDQQ 523
           F  + Y   + E+   G   TVL+V+ATD D       A + YSL              Q
Sbjct: 545 FSKSSYIVKIPENINAGEWATVLLVNATDLDASREFGQASLIYSLEGS----------SQ 594

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT--TDVEISVVDVNDNEPVF 581
           F +N ++G ITT  LLDRE  S Y+L V A DGGV     T    V I+++D+NDN PV+
Sbjct: 595 FRLNSRSGEITTTALLDRELKSEYILIVRAVDGGVGPQQKTGIATVNITILDINDNAPVW 654

Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641
           + + Y AN++E + + T V  V A D D G NG + Y + P   E   + I+ ++G IRT
Sbjct: 655 RDEPYHANVVEMSPINTDVISVLALDPDNGENGTVVYSISP---ENPFYTINSSTGKIRT 711

Query: 642 NKA-LDRESVATHD---LKAV---AIDGGTPP--QSSTVIVHIKIEDINDSPPVFESDCL 692
           +   LDRES    D   ++ +   A+D G+P    S++  V + + D+ND+ P F +   
Sbjct: 712 SGVTLDRESSNPRDAILMRTIIISAVDRGSPQLRASASTTVFVNLLDLNDNDPKFLNLPF 771

Query: 693 TFYISENSPIGTTI 706
              + E   IG+++
Sbjct: 772 VAEVPEGLAIGSSV 785



 Score =  218 bits (532), Expect = 2e-54
 Identities = 199/668 (29%), Positives = 306/668 (45%), Gaps = 70/668 (10%)

Query: 174 IKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233
           + ATD D G   ++ ++    +    F+ID   G V++ K LDYE   +Y+L + A D  
Sbjct: 14  VNATDPDQGTGGSVLFSFQPPSPF--FAIDGARGTVTVTKPLDYETTSAYQLTVNATDQD 71

Query: 234 S-PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI----------------GYSI 276
                S    L I+I DV D  P F    +  ++ E+VP+                GY +
Sbjct: 72  KLRPLSRLANLAISITDVQDMDPIFTNLPYSTNIEEDVPLISQTQTHLGPLHTALQGYEV 131

Query: 277 VRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET---QAKYQ 333
            ++ A D D G    + YT+     +GN +    +D  SG +  SGQLDRE     A + 
Sbjct: 132 RKITAMDQDLGRPRGIGYTIV----SGNTNSVFALDYISGSLTVSGQLDRENPLYSAGFT 187

Query: 334 LLVTATDGGDP--PRSATA--TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV-VTL 388
           L V AT+  +   P  AT   T              F   +Y +++ E    G  + + +
Sbjct: 188 LTVKATELKEDRFPSDATVMTTFTILLIDKNDNAPKFNSSEYRLQITELAQVGFALPLFI 247

Query: 389 TATDADEDNRLHYEI--TGGNTRG-RFSITSQNGRGLIT--VAQPLDFKQERRYVLTVSA 443
            A D DE     +++  TG N+     S T+  GR  I   VA PLD++  R Y  ++ A
Sbjct: 248 QAEDKDEGVNSMFQVFLTGNNSEYFTLSPTAVQGRADIRMRVAMPLDYEHIRSYSFSLYA 307

Query: 444 TDS-GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502
            +S       A V I + + N+  P+F    Y  S+ E+   GT++L + ATD+D G   
Sbjct: 308 NESMSDHVGFARVFIELINENDNRPIFSKPLYNISLPENTAPGTSLLRILATDADAGTFG 367

Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
            + Y  S +           QF ++ +TG +     LD E M  + LTV ARDGG     
Sbjct: 368 IVRYYFSDD---------PDQFSLDEETGWVILQASLDYELMRRFTLTVLARDGG--GEE 416

Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP 622
            T  + ++V+DVNDN P+F+++ Y  ++ E+      V+++ ATD D   N  + Y +  
Sbjct: 417 TTGRIRVNVLDVNDNAPLFQKEAYVGSLRENEQAVQPVARLRATDEDSPPNNFLTYTIIS 476

Query: 623 KDREEGSFVIDPASG--VIRTNKALDRESVATH--DLKAVAIDGGTPPQSSTVIVHIKIE 678
                  F I    G  VI   + LD E V +    L+ +  DGG+P  +STV V +++ 
Sbjct: 477 ASAFPSYFSIIMVEGYAVISVTRPLDYEQVPSGMIHLEVMVKDGGSPALNSTVPVTVEVI 536

Query: 679 DINDSPPVFESDCLTFYISENSPIG--TTIGEIRAHDPD---EGPNAVVHYSIKGGDDSN 733
           D ND+PP F        I EN   G   T+  + A D D   E   A + YS++G   S+
Sbjct: 537 DENDNPPEFSKSSYIVKIPENINAGEWATVLLVNATDLDASREFGQASLIYSLEG---SS 593

Query: 734 SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR-----VEILVTDVN 788
            F L +R G    E+ T   LD E  + +Y L++RA    +    +     V I + D+N
Sbjct: 594 QFRLNSRSG----EITTTALLDREL-KSEYILIVRAVDGGVGPQQKTGIATVNITILDIN 648

Query: 789 DNAPVMKD 796
           DNAPV +D
Sbjct: 649 DNAPVWRD 656



 Score =  201 bits (491), Expect = 2e-49
 Identities = 240/899 (26%), Positives = 389/899 (43%), Gaps = 94/899 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTV-LTLKATDQDIGKNAEVEYTIELVTAD- 68
            I ++D ND++P F   +Y   + E A  G  + L ++A D+D G N+  +  +    ++ 
Sbjct: 212  ILLIDKNDNAPKFNSSEYRLQITELAQVGFALPLFIQAEDKDEGVNSMFQVFLTGNNSEY 271

Query: 69   -TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
             TL+P             VQ   R D R    +    LD E +  Y+  + A +    +S
Sbjct: 272  FTLSP-----------TAVQG--RADIRMRVAMP---LDYEHIRSYSFSLYANES---MS 312

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
            D +   A + + +I++NDN P FS+  Y +S+ E+ +   +  + +I ATDAD G    +
Sbjct: 313  DHVGF-ARVFIELINENDNRPIFSKPLYNISLPENTAPGTS--LLRILATDADAGTFGIV 369

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            RY     +   QFS+D  +G V L  +LDYE +R + L + A+DGG      T ++ +N+
Sbjct: 370  RYYF--SDDPDQFSLDEETGWVILQASLDYELMRRFTLTVLARDGGG--EETTGRIRVNV 425

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
             DVNDNAP F    +  S+ EN      + R++A D D   N  LTYT+       +   
Sbjct: 426  LDVNDNAPLFQKEAYVGSLRENEQAVQPVARLRATDEDSPPNNFLTYTIISASAFPSYFS 485

Query: 308  PITIDPRSGWVYTSGQLDRET--QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
             I ++  +  +  +  LD E        L V   DGG P  ++T                
Sbjct: 486  IIMVEGYAV-ISVTRPLDYEQVPSGMIHLEVMVKDGGSPALNSTVPVTVEVIDENDNPPE 544

Query: 366  FMPGQYEVELAEDEPPG--TPVVTLTATDADEDNR-----LHYEITGGNTRGRFSITSQN 418
            F    Y V++ E+   G    V+ + ATD D         L Y + G +   +F + S++
Sbjct: 545  FSKSSYIVKIPENINAGEWATVLLVNATDLDASREFGQASLIYSLEGSS---QFRLNSRS 601

Query: 419  GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTA 476
            G   IT    LD + +  Y+L V A D G   +  T +  +NIT  +    + +NAP   
Sbjct: 602  GE--ITTTALLDRELKSEYILIVRAVDGGVGPQQKTGIATVNITILD----INDNAP--- 652

Query: 477  SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
             V+ D P    V+ +S       IN  +   L+ +  N    +    + I+P+    T N
Sbjct: 653  -VWRDEPYHANVVEMSP------INTDVISVLALDPDNGE--NGTVVYSISPENPFYTIN 703

Query: 537  KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
                +   SG  L   + +     L  T  + IS VD     P  +    T        V
Sbjct: 704  SSTGKIRTSGVTLDRESSNPRDAILMRT--IIISAVD--RGSPQLRASASTT-------V 752

Query: 597  GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
              ++  +   D    LN     E+ P+    GS V    S   ++  A   E +  + L+
Sbjct: 753  FVNLLDLNDNDPKF-LNLPFVAEV-PEGLAIGSSVFKAFSPPPQSWTA---EQIGLYYLR 807

Query: 657  AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
             +A D G  P++ST  + +K+ D+ND  P F+       + E+ P    +  +   D D 
Sbjct: 808  IIAYDAGNFPRTSTSTLTVKVLDVNDETPTFDPRVYNVSLKESIPRDHVVARLACSDNDA 867

Query: 717  GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA-----AS 771
            G NA + Y I GG+    FS+  R G  +    T+V LD E+ +  Y L++ A     A 
Sbjct: 868  GLNAELSYFITGGNQDGKFSVGFRDGIVR----TVVGLDRET-QAAYTLIVEAIDNGPAG 922

Query: 772  PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTD--KLQ 828
                    V + V DVNDN P+         +  +  P G    +V A DAD  +   + 
Sbjct: 923  SRRTGTATVFVEVQDVNDNRPIFLQ-NSYETSVLESVPQGTSILQVQATDADQGENGSVL 981

Query: 829  YRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887
            YRIL+GN+ NL  ++  TG +T    L     + ++  +   +  N  +  M+ SVR+I
Sbjct: 982  YRILTGNSNNLFSIDRQTGLVTRG--LRALDRETSSSHMLEVEAYNSDEGSMRSSVRVI 1038



 Score =  154 bits (373), Expect = 4e-35
 Identities = 118/348 (33%), Positives = 170/348 (48%), Gaps = 32/348 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + +L+  D +  F    YEAS+RE  ++GT V+ ++A   D     ++ Y  +       
Sbjct: 1124 VTLLNELDEAVAFSSAGYEASLRENIATGTEVIQVQAQSAD--NLNQLTYRFD------- 1174

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD----QASPV 126
             P+ +             +F+ID  +G +     LDRE+   YT+ V A D    + S V
Sbjct: 1175 -PDTSPAALA--------LFKIDSVTGRITVTGLLDRERGDAYTLTVVADDGGPKKDSTV 1225

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
                S +  + + I+D+NDN P F + T   SVD   +      +A + A D D G N  
Sbjct: 1226 ITSDSISQQVSITILDENDNSPVF-DITSDTSVDITENTPMGEKVAVVLARDKDAGLNGL 1284

Query: 187  IRYAIIGGNTQMQFSIDSLS---GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
            I + ++ GN +  F I +++   G+V +   LD E V  Y L +RA D GSP R     L
Sbjct: 1285 INFTLVAGNMKDVFKIKTVNHTYGEVYVNAPLDRESVDRYLLKVRATDNGSPPRHTDHSL 1344

Query: 244  LINIRDVNDNAPRFYTSL-FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
             INI DVNDNAP   +   +  S+SENV  G S++RV A D D G NA L Y +T     
Sbjct: 1345 TINILDVNDNAPVIESQKGYNVSISENVGGGTSVLRVMATDRDIGPNAMLFYYIT----A 1400

Query: 303  GNVDLPITIDPRSGWVYT-SGQLDRETQAKYQLLVTATDGGDPPRSAT 349
            GN DL   +D  +G + T     DRE Q +Y L VT  D G PP S +
Sbjct: 1401 GNQDLTFRMDRMTGEMVTRPAPPDRERQQEYILTVTVEDDGTPPLSVS 1448



 Score =  149 bits (360), Expect = 1e-33
 Identities = 170/649 (26%), Positives = 262/649 (40%), Gaps = 64/649 (9%)

Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325
           + +N P+G S+  V A D D+G    + ++               ID   G V  +  LD
Sbjct: 1   ILQNTPVGRSVFMVNATDPDQGTGGSVLFSFQPPSPF------FAIDGARGTVTVTKPLD 54

Query: 326 RETQAKYQLLVTATDGGD-PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP---- 380
            ET + YQL V ATD     P S  A               F    Y   + ED P    
Sbjct: 55  YETTSAYQLTVNATDQDKLRPLSRLANLAISITDVQDMDPIFTNLPYSTNIEEDVPLISQ 114

Query: 381 ------------PGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
                        G  V  +TA D D      + Y I  GNT   F++   +G   +TV+
Sbjct: 115 TQTHLGPLHTALQGYEVRKITAMDQDLGRPRGIGYTIVSGNTNSVFALDYISGS--LTVS 172

Query: 427 QPLDFKQ---ERRYVLTVSAT----DSGGRSDTAMVQINI--TDANNYAPVFENAPYTAS 477
             LD +       + LTV AT    D      T M    I   D N+ AP F ++ Y   
Sbjct: 173 GQLDRENPLYSAGFTLTVKATELKEDRFPSDATVMTTFTILLIDKNDNAPKFNSSEYRLQ 232

Query: 478 VFEDAPIGTTV-LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
           + E A +G  + L + A D D G+N+     L+   +N          V       +   
Sbjct: 233 ITELAQVGFALPLFIQAEDKDEGVNSMFQVFLTG--NNSEYFTLSPTAVQGRADIRMRVA 290

Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTD---VEISVVDVNDNEPVFKQQLYTANIMED 593
             LD E +  Y  ++ A +    S+SD      V I +++ NDN P+F + LY  ++ E+
Sbjct: 291 MPLDYEHIRSYSFSLYANE----SMSDHVGFARVFIELINENDNRPIFSKPLYNISLPEN 346

Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653
              GTS+ ++ ATDAD G  G + Y       +   F +D  +G +    +LD E +   
Sbjct: 347 TAPGTSLLRILATDADAGTFGIVRYYFSD---DPDQFSLDEETGWVILQASLDYELMRRF 403

Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713
            L  +A DGG   + +T  + + + D+ND+ P+F+ +     + EN      +  +RA D
Sbjct: 404 TLTVLARDGG--GEETTGRIRVNVLDVNDNAPLFQKEAYVGSLRENEQAVQPVARLRATD 461

Query: 714 PDEGPNAVVHYSIKGGDDSNS-FSLETRQGSDKAELVTMVDLDYE---SPRKKYELVIR- 768
            D  PN  + Y+I       S FS+   +G   A +     LDYE   S     E++++ 
Sbjct: 462 EDSPPNNFLTYTIISASAFPSYFSIIMVEG--YAVISVTRPLDYEQVPSGMIHLEVMVKD 519

Query: 769 AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR---VPAYDADVTD 825
             SP L + V V + V D NDN P       I     +    G +     V A D D + 
Sbjct: 520 GGSPALNSTVPVTVEVIDENDNPPEFSKSSYIV-KIPENINAGEWATVLLVNATDLDASR 578

Query: 826 KLQYR--ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
           +      I S   ++   LN  +G +T +  L+  +     + V   DG
Sbjct: 579 EFGQASLIYSLEGSSQFRLNSRSGEITTTALLDRELKSEYILIVRAVDG 627



 Score =  141 bits (341), Expect = 3e-31
 Identities = 106/353 (30%), Positives = 170/353 (48%), Gaps = 36/353 (10%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++NVLD ND++P+F+ + Y  S+RE   +   V  L+ATD+D   N  + YTI   +A  
Sbjct: 422 RVNVLDVNDNAPLFQKEAYVGSLRENEQAVQPVARLRATDEDSPPNNFLTYTIISASA-- 479

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKV--ARYTVLVKATDQASPVS 127
                              +  ++G +   +TR  LD E+V      + V   D  SP  
Sbjct: 480 -------------FPSYFSIIMVEGYAVISVTR-PLDYEQVPSGMIHLEVMVKDGGSPA- 524

Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
             L+ST  + V +ID+NDN P+FS+ +Y V + E+I+  +   +  + ATD D       
Sbjct: 525 --LNSTVPVTVEVIDENDNPPEFSKSSYIVKIPENINAGEWATVLLVNATDLDASREFGQ 582

Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
              I       QF ++S SG+++    LD E    Y L++RA DGG   +  T    +NI
Sbjct: 583 ASLIYSLEGSSQFRLNSRSGEITTTALLDRELKSEYILIVRAVDGGVGPQQKTGIATVNI 642

Query: 248 R--DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
              D+NDNAP +    +  +V E  PI   ++ V A D D G N  + Y+++ ++     
Sbjct: 643 TILDINDNAPVWRDEPYHANVVEMSPINTDVISVLALDPDNGENGTVVYSISPENPF--- 699

Query: 306 DLPITIDPRSGWVYTSG-QLDRETQ------AKYQLLVTATDGGDPPRSATAT 351
               TI+  +G + TSG  LDRE+           ++++A D G P   A+A+
Sbjct: 700 ---YTINSSTGKIRTSGVTLDRESSNPRDAILMRTIIISAVDRGSPQLRASAS 749



 Score =  117 bits (282), Expect = 4e-24
 Identities = 118/426 (27%), Positives = 181/426 (42%), Gaps = 39/426 (9%)

Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
           + ++ P+G +V +V+ATD D G    + +S                F I+   G +T  K
Sbjct: 1   ILQNTPVGRSVFMVNATDPDQGTGGSVLFSFQPP---------SPFFAIDGARGTVTVTK 51

Query: 538 LLDRETMSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED--- 593
            LD ET S Y LTV A D   +  LS   ++ IS+ DV D +P+F    Y+ NI ED   
Sbjct: 52  PLDYETTSAYQLTVNATDQDKLRPLSRLANLAISITDVQDMDPIFTNLPYSTNIEEDVPL 111

Query: 594 -------------ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640
                        AL G  V ++ A D D+G    I Y +         F +D  SG + 
Sbjct: 112 ISQTQTHLGPLHTALQGYEVRKITAMDQDLGRPRGIGYTI-VSGNTNSVFALDYISGSLT 170

Query: 641 TNKALDRESVA-----THDLKAVAIDGGTPPQSSTVIV--HIKIEDINDSPPVFESDCLT 693
            +  LDRE+       T  +KA  +     P  +TV+    I + D ND+ P F S    
Sbjct: 171 VSGQLDRENPLYSAGFTLTVKATELKEDRFPSDATVMTTFTILLIDKNDNAPKFNSSEYR 230

Query: 694 FYISENSPIGTTIG-EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR--QGSDKAELVT 750
             I+E + +G  +   I+A D DEG N++    +  G++S  F+L     QG     +  
Sbjct: 231 LQITELAQVGFALPLFIQAEDKDEGVNSMFQVFLT-GNNSEYFTLSPTAVQGRADIRMRV 289

Query: 751 MVDLDYESPRK-KYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809
            + LDYE  R   + L    +        RV I + + NDN P+        +  ++  P
Sbjct: 290 AMPLDYEHIRSYSFSLYANESMSDHVGFARVFIELINENDNRPIFSKPLYNISLPENTAP 349

Query: 810 VGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSV 869
                R+ A DAD       R    ++ +   L+E TG + L   L+  + +  T+ V  
Sbjct: 350 GTSLLRILATDADAGTFGIVRYYFSDDPDQFSLDEETGWVILQASLDYELMRRFTLTVLA 409

Query: 870 TDGVNE 875
            DG  E
Sbjct: 410 RDGGGE 415


>UniRef50_Q4RPF4 Cluster: Chromosome 1 SCAF15008, whole genome
           shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 1
           SCAF15008, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1210

 Score =  278 bits (681), Expect = 2e-72
 Identities = 197/624 (31%), Positives = 306/624 (49%), Gaps = 38/624 (6%)

Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISV-TDNPVIAKIKATDAD 180
           + + + D +     I   I D NDN P F      +S+ E+ ++ T  PV +   A D D
Sbjct: 81  EVAVLPDEIFRLVKIRFLIEDVNDNAPLFQSTVINISIPENTAINTRYPVPS---AFDPD 137

Query: 181 VGANSAIRYAIIGGNTQMQFSI-DSLSGD----VSLVKTLDYEQVRSYRLVIRAQDGGSP 235
           VG N    Y ++   ++    I ++  GD    + + + LD EQ  +Y + I+ +DGG+P
Sbjct: 138 VGINGIQHYELVKSVSEFGLDIIETPEGDKWPQLIVQQNLDREQKDTYVMKIKVEDGGNP 197

Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295
            +S+T  L + I DVNDN P F  S  + +V EN P+G S+ ++ A DAD G NA++ +T
Sbjct: 198 PKSSTAILQVTISDVNDNRPIFKDSELEVTVPENAPMGTSVAQLHATDADLGSNAQIHFT 257

Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT----AT 351
            +++   G      +ID  +G +     LDRE    ++L+V A+DG   P  AT     T
Sbjct: 258 FSNQISAG-TKRHFSIDGSTGLITVKQSLDRELTPVHKLIVLASDGSSTPSRATVIVNVT 316

Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEI---TGGNT 408
                                V L+E+ P  T +  +T TD D D  L+ ++   T  + 
Sbjct: 317 DVNDNVPTIDTRYIINLVNGTVLLSENAPLNTKIALITVTDKDAD--LYGKVACYTDHDV 374

Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYA 466
             R      N + L+  A PLD++  R Y + + A+D G    + +AMV I I D N+  
Sbjct: 375 PFRLKPVF-NDQFLLETAAPLDYETTREYAIKIVASDRGTPPLNTSAMVLIKIKDENDNV 433

Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
           P+F       S+ E+    T ++ +SATD+D   NA+I Y+L  +          + F +
Sbjct: 434 PIFPQPEIQLSIPENNDPSTQLIKLSATDADSEHNAEIIYTLGPDA--------PEGFNV 485

Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586
           + ++G ++  K LDRE    Y  TV A+D G  SL     V++ V D+NDN P F    Y
Sbjct: 486 DRRSGVLSVGKRLDREKQDRYAFTVIAKDNGSTSLQSNVTVKLIVQDLNDNSPAFTHPEY 545

Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGVIRTNKAL 645
              + E+  +  +V  +  TDAD G N  +    L+ KD    +F+IDP +GVI+ N   
Sbjct: 546 NFYVPENLPLFGTVGLITVTDADSGENAVVTLSILNGKD----NFIIDPQTGVIKPNITF 601

Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF---ESDCLTFYISENSPI 702
           DRE  +++     A+DGG PP SS   V I + D+ND+ PVF    S+     +  N+  
Sbjct: 602 DREQQSSYTFMVKAVDGGQPPSSSYAKVTINVVDVNDNRPVFVIPSSNYSYDLVRTNASP 661

Query: 703 GTTIGEIRAHDPDEGPNAVVHYSI 726
           G  +  + A D D G NA + YSI
Sbjct: 662 GAVVTRVYAIDNDTGMNAELQYSI 685



 Score =  262 bits (643), Expect = 7e-68
 Identities = 205/688 (29%), Positives = 329/688 (47%), Gaps = 60/688 (8%)

Query: 15  DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
           D ND++P+F+      S+ E  +  T      A D D+G N    Y  ELV + +    D
Sbjct: 101 DVNDNAPLFQSTVINISIPENTAINTRYPVPSAFDPDVGINGIQHY--ELVKSVSEFGLD 158

Query: 75  AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134
                               +   L+ + +LDRE+   Y + +K  D  +P     SSTA
Sbjct: 159 IIETPEGD------------KWPQLIVQQNLDREQKDTYVMKIKVEDGGNPPK---SSTA 203

Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI--- 191
            + V I D NDN P F +    V+V E+  +  +  +A++ ATDAD+G+N+ I +     
Sbjct: 204 ILQVTISDVNDNRPIFKDSELEVTVPENAPMGTS--VAQLHATDADLGSNAQIHFTFSNQ 261

Query: 192 IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS-PSRSNTTQLLINIRDV 250
           I   T+  FSID  +G +++ ++LD E    ++L++ A DG S PSR+    +++N+ DV
Sbjct: 262 ISAGTKRHFSIDGSTGLITVKQSLDRELTPVHKLIVLASDGSSTPSRAT---VIVNVTDV 318

Query: 251 NDNAP----RFYTSLFQESV--SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           NDN P    R+  +L   +V  SEN P+   I  +   D D  +  ++    TD D    
Sbjct: 319 NDNVPTIDTRYIINLVNGTVLLSENAPLNTKIALITVTDKDADLYGKVA-CYTDHDVPFR 377

Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
           +  P+  D     + T+  LD ET  +Y + + A+D G PP + +A              
Sbjct: 378 LK-PVFND--QFLLETAAPLDYETTREYAIKIVASDRGTPPLNTSAMVLIKIKDENDNVP 434

Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT-GGNTRGRFSITSQNGRGLI 423
            F   + ++ + E+  P T ++ L+ATDAD ++      T G +    F++  ++  G++
Sbjct: 435 IFPQPEIQLSIPENNDPSTQLIKLSATDADSEHNAEIIYTLGPDAPEGFNVDRRS--GVL 492

Query: 424 TVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFED 481
           +V + LD +++ RY  TV A D+G  S      V++ + D N+ +P F +  Y   V E+
Sbjct: 493 SVGKRLDREKQDRYAFTVIAKDNGSTSLQSNVTVKLIVQDLNDNSPAFTHPEYNFYVPEN 552

Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
            P+  TV +++ TD+D G NA +T S+ +   N         F+I+PQTG I  N   DR
Sbjct: 553 LPLFGTVGLITVTDADSGENAVVTLSILNGKDN---------FIIDPQTGVIKPNITFDR 603

Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF--KQQLYTANIME-DALVGT 598
           E  S Y   V A DGG P  S    V I+VVDVNDN PVF      Y+ +++  +A  G 
Sbjct: 604 EQQSSYTFMVKAVDGGQPPSSSYAKVTINVVDVNDNRPVFVIPSSNYSYDLVRTNASPGA 663

Query: 599 SVSQVGATDADVGLNGRIHYE------LDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652
            V++V A D D G+N  + Y       +  +    G F ID ++G I   + +       
Sbjct: 664 VVTRVYAIDNDTGMNAELQYSIISSIIITSRVSPRGLFAIDKSTGNITLQEKIVAADQGL 723

Query: 653 HDLKAVAIDGGTPPQSSTV-IVHIKIED 679
           H L     D G P     + +VH+ + D
Sbjct: 724 HRLVVKVRDLGQPESLHAITLVHLFVND 751



 Score =  258 bits (633), Expect = 1e-66
 Identities = 207/682 (30%), Positives = 308/682 (45%), Gaps = 49/682 (7%)

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
           I DVNDNAP F +++   S+ EN  I        A+D D G+N    Y +        +D
Sbjct: 99  IEDVNDNAPLFQSTVINISIPENTAINTRYPVPSAFDPDVGINGIQHYELVKSVSEFGLD 158

Query: 307 LPITIDPRSGW--VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
           + I       W  +     LDRE +  Y + +   DGG+PP+S+TA              
Sbjct: 159 I-IETPEGDKWPQLIVQQNLDREQKDTYVMKIKVEDGGNPPKSSTAILQVTISDVNDNRP 217

Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITG---GNTRGRFSITSQNG 419
            F   + EV + E+ P GT V  L ATDAD   + ++H+  +      T+  FSI    G
Sbjct: 218 IFKDSELEVTVPENAPMGTSVAQLHATDADLGSNAQIHFTFSNQISAGTKRHFSIDGSTG 277

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPY----- 474
             LITV Q LD +    + L V A+D       A V +N+TD N+  P  +         
Sbjct: 278 --LITVKQSLDRELTPVHKLIVLASDGSSTPSRATVIVNVTDVNDNVPTIDTRYIINLVN 335

Query: 475 -TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
            T  + E+AP+ T + +++ TD D  +  ++      ++        + QF++       
Sbjct: 336 GTVLLSENAPLNTKIALITVTDKDADLYGKVACYTDHDVPFRLKPVFNDQFLLE------ 389

Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593
            T   LD ET   Y + + A D G P L+ +  V I + D NDN P+F Q     +I E+
Sbjct: 390 -TAAPLDYETTREYAIKIVASDRGTPPLNTSAMVLIKIKDENDNVPIFPQPEIQLSIPEN 448

Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653
               T + ++ ATDAD   N  I Y L P D  EG F +D  SGV+   K LDRE    +
Sbjct: 449 NDPSTQLIKLSATDADSEHNAEIIYTLGP-DAPEG-FNVDRRSGVLSVGKRLDREKQDRY 506

Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713
               +A D G+    S V V + ++D+ND+ P F      FY+ EN P+  T+G I   D
Sbjct: 507 AFTVIAKDNGSTSLQSNVTVKLIVQDLNDNSPAFTHPEYNFYVPENLPLFGTVGLITVTD 566

Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP 773
            D G NAVV  SI  G D  +F ++ + G  K  +    D + +S        +    PP
Sbjct: 567 ADSGENAVVTLSILNGKD--NFIIDPQTGVIKPNIT--FDREQQSSYTFMVKAVDGGQPP 622

Query: 774 LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYK------DCFPVGPFGRVPAYDAD--VTD 825
             +  +V I V DVNDN PV   F I  +NY       +  P     RV A D D  +  
Sbjct: 623 SSSYAKVTINVVDVNDNRPV---FVIPSSNYSYDLVRTNASPGAVVTRVYAIDNDTGMNA 679

Query: 826 KLQYRILSG-------NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIK 877
           +LQY I+S        +   L  ++++TG++TL  ++      L  + V V D G  E  
Sbjct: 680 ELQYSIISSIIITSRVSPRGLFAIDKSTGNITLQEKIVAADQGLHRLVVKVRDLGQPESL 739

Query: 878 AMMQLSVRLITEEMLLNSITVR 899
             + L V L   + + NS  ++
Sbjct: 740 HAITL-VHLFVNDTVSNSTFIQ 760



 Score =  217 bits (530), Expect = 4e-54
 Identities = 180/590 (30%), Positives = 266/590 (45%), Gaps = 46/590 (7%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI-ELVTAD 68
           Q+ + D ND+ P+F+  + E +V E A  GT+V  L ATD D+G NA++ +T    ++A 
Sbjct: 206 QVTISDVNDNRPIFKDSELEVTVPENAPMGTSVAQLHATDADLGSNAQIHFTFSNQISAG 265

Query: 69  TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
           T                 +  F IDG +G +  + SLDRE    + ++V A+D +S    
Sbjct: 266 T-----------------KRHFSIDGSTGLITVKQSLDRELTPVHKLIVLASDGSS---- 304

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDN-PV---IAKIKATDADVGAN 184
              S AT+ VN+ D NDN P    +     V+  + +++N P+   IA I  TD D    
Sbjct: 305 -TPSRATVIVNVTDVNDNVPTIDTRYIINLVNGTVLLSENAPLNTKIALITVTDKDADLY 363

Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRSNTT 241
             +       +  + F +  +  D  L++T   LDYE  R Y + I A D G+P  + + 
Sbjct: 364 GKVACYT---DHDVPFRLKPVFNDQFLLETAAPLDYETTREYAIKIVASDRGTPPLNTSA 420

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
            +LI I+D NDN P F     Q S+ EN      ++++ A DAD   NAE+ YT+     
Sbjct: 421 MVLIKIKDENDNVPIFPQPEIQLSIPENNDPSTQLIKLSATDADSEHNAEIIYTLGPDAP 480

Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
            G       +D RSG +    +LDRE Q +Y   V A D G     +  T          
Sbjct: 481 EG-----FNVDRRSGVLSVGKRLDREKQDRYAFTVIAKDNGSTSLQSNVTVKLIVQDLND 535

Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421
               F   +Y   + E+ P    V  +T TDAD        ++  N +  F I  Q   G
Sbjct: 536 NSPAFTHPEYNFYVPENLPLFGTVGLITVTDADSGENAVVTLSILNGKDNFIIDPQT--G 593

Query: 422 LITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVF--ENAPYTAS 477
           +I      D +Q+  Y   V A D G    S  A V IN+ D N+  PVF   ++ Y+  
Sbjct: 594 VIKPNITFDREQQSSYTFMVKAVDGGQPPSSSYAKVTINVVDVNDNRPVFVIPSSNYSYD 653

Query: 478 -VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
            V  +A  G  V  V A D+D G+NA++ YS+ S I   +       F I+  TG IT  
Sbjct: 654 LVRTNASPGAVVTRVYAIDNDTGMNAELQYSIISSIIITSRVSPRGLFAIDKSTGNITLQ 713

Query: 537 KLLDRETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQL 585
           + +       + L V  RD G P SL   T V + V D   N    ++QL
Sbjct: 714 EKIVAADQGLHRLVVKVRDLGQPESLHAITLVHLFVNDTVSNSTFIQEQL 763



 Score =  169 bits (412), Expect = 7e-40
 Identities = 133/454 (29%), Positives = 218/454 (48%), Gaps = 24/454 (5%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           ++  I D N+ AP+F++     S+ E+  I T   V SA D DVGIN    Y L   +S 
Sbjct: 95  IRFLIEDVNDNAPLFQSTVINISIPENTAINTRYPVPSAFDPDVGINGIQHYELVKSVSE 154

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
             +   +       +   +   + LDRE    Y++ +   DGG P  S T  +++++ DV
Sbjct: 155 FGLDIIETPE--GDKWPQLIVQQNLDREQKDTYVMKIKVEDGGNPPKSSTAILQVTISDV 212

Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK--DREEGSFVI 632
           NDN P+FK       + E+A +GTSV+Q+ ATDAD+G N +IH+    +     +  F I
Sbjct: 213 NDNRPIFKDSELEVTVPENAPMGTSVAQLHATDADLGSNAQIHFTFSNQISAGTKRHFSI 272

Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692
           D ++G+I   ++LDRE    H L  +A DG + P  +TVIV+  + D+ND+ P  ++  +
Sbjct: 273 DGSTGLITVKQSLDRELTPVHKLIVLASDGSSTPSRATVIVN--VTDVNDNVPTIDTRYI 330

Query: 693 ------TFYISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745
                 T  +SEN+P+ T I  I   D D +    V  Y+    D    F L+    +D+
Sbjct: 331 INLVNGTVLLSENAPLNTKIALITVTDKDADLYGKVACYT----DHDVPFRLKP-VFNDQ 385

Query: 746 AELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN 802
             L T   LDYE+ R +Y + I A+   +PPL     V I + D NDN P+    +I  +
Sbjct: 386 FLLETAAPLDYETTR-EYAIKIVASDRGTPPLNTSAMVLIKIKDENDNVPIFPQPEIQLS 444

Query: 803 NYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNA-NLILLNETTGSMTLSPQLNTNVPK 861
             ++  P     ++ A DAD     +     G +A     ++  +G +++  +L+     
Sbjct: 445 IPENNDPSTQLIKLSATDADSEHNAEIIYTLGPDAPEGFNVDRRSGVLSVGKRLDREKQD 504

Query: 862 LATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNS 895
                V   D          ++V+LI +++  NS
Sbjct: 505 RYAFTVIAKDN-GSTSLQSNVTVKLIVQDLNDNS 537


>UniRef50_Q4T0W6 Cluster: Chromosome 1 SCAF10821, whole genome shotgun
            sequence; n=41; Clupeocephala|Rep: Chromosome 1
            SCAF10821, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 1151

 Score =  277 bits (680), Expect = 2e-72
 Identities = 269/972 (27%), Positives = 428/972 (44%), Gaps = 90/972 (9%)

Query: 4    PFCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
            P  +H+  I+V D ND+SP F+ +  +  +RE A  G   L  +A D DIG+N    YT+
Sbjct: 109  PLELHRISIHVQDINDNSPQFKEESIKLEIRESAVKGARFLLGEAHDADIGQNTVQGYTL 168

Query: 63   ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122
            +      LN                     + +   LL    LDRE      +L+ A D 
Sbjct: 169  QQNDHFKLNVNTKSS---------------NRKYCELLLDKELDREDKQELQLLLTAVDG 213

Query: 123  ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
             SP   + S T  IHV ++D NDN P FS+  Y  S+ E+ S  D  VI  + A DAD G
Sbjct: 214  GSP---QRSGTVVIHVTVLDANDNAPVFSQSVYKTSLPEN-SPLDTLVIT-VSAADADEG 268

Query: 183  ANSAIRYAIIGG-NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
             NS I Y        +  F +D+ +G V +   +DYE++ SY + I A+DG       T 
Sbjct: 269  VNSEITYGFDHVLEDENVFLLDTKTGVVRVNGAIDYEKIPSYEMQISAKDGLGLVAYAT- 327

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
             L+I I DVNDNAP  +       + ENV  G  +  +   D D   N ++  ++     
Sbjct: 328  -LIIEITDVNDNAPVIHLKSLTNPIPENVSPGSEVGIINVQDRDSENNRQVRCSIQQ--- 383

Query: 302  TGNVDLPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
              NV   +    ++ + + T+GQLDRE  + Y + ++ATD G PP S++ +         
Sbjct: 384  --NVPFKLVASIKNYYSLVTTGQLDRELVSDYNITISATDEGSPPLSSSKSVHLSVADVN 441

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGR--FSITS 416
                 F    Y   ++E+   G+ + +++A D D  ++  + Y +      G    S  S
Sbjct: 442  DNPPVFEEQSYSAYVSENNRAGSTLCSVSARDPDWRQNGTVIYSLLAAEVSGAPVSSYVS 501

Query: 417  QNG-RGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAP-VFENA 472
             NG  G+I   +  D++Q R + + V A D+G    S    V + ++D N+  P +   A
Sbjct: 502  VNGDTGVIHAVRSFDYEQLRSFKVHVMARDNGSPPLSSNVSVSVFVSDVNDNPPQILYPA 561

Query: 473  P-----YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527
            P      T  V + A  G+ V  V A D+D G NA ++Y +    S+  +      F I 
Sbjct: 562  PEGNSFMTELVPKAAHGGSLVSKVIAVDADSGQNAWLSYHIVQS-SDPGL------FTIG 614

Query: 528  PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY- 586
              +G I T + +         L V  +D G PSLS T  + + + D     P  K   Y 
Sbjct: 615  VHSGEIRTQRDISESDSMKQNLIVAVKDNGQPSLSATCSMYLLISDNLAEVPELKDISYE 674

Query: 587  --TANIMEDALVG-TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA-------- 635
               + +    ++    VS    T   + L  R      P+   +G+  I  A        
Sbjct: 675  EKNSKLTSYLIIALVCVSTFFLTFIIIILGVRFCRRRKPRMLFDGAVTIPGAYLPPNYAD 734

Query: 636  ---SGVIR---------TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS 683
               +G +R         T   LDRE V+ +++   A D G+PP SS+  VH+ + D+ND+
Sbjct: 735  VDGTGTLRSAYNYDAYLTTGQLDRELVSDYNITISATDEGSPPLSSSKSVHLSVADVNDN 794

Query: 684  PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS-FSLETRQG 742
            PPVFE    + Y+ EN+  G+T+  + A DPD   N  V YS+   + S +  S      
Sbjct: 795  PPVFEEQSYSAYVRENNRAGSTLCSVSARDPDWRQNGTVIYSLLAAEVSGAPVSSYVSVN 854

Query: 743  SDKAELVTMVDLDYESPRK-KYELVIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQII 800
             D   +  +   DYE  R  K  ++ R   SPPL ++V V + V+DVNDN P +      
Sbjct: 855  GDTGVIHAVRSFDYEQLRSFKVHVMARDNGSPPLSSNVSVSVFVSDVNDNPPQILYPAPE 914

Query: 801  FNNY-KDCFPVGPFG-----RVPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTLS 852
             N++  +  P    G     +V A DAD      L Y I+  ++  L  +   +G +   
Sbjct: 915  GNSFMTELVPKAAHGGSLVSKVIAVDADSGQNAWLSYHIVQSSDPGLFTIGVHSGEIRTQ 974

Query: 853  PQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSP 911
              ++ +      + V+V D G   + A   + + LI++ +   +    L D++ E+  S 
Sbjct: 975  RDISESDSMKQNLIVAVKDNGQPSLSATCSMYL-LISDNL---AEVPELKDISYEEKNSK 1030

Query: 912  LLGFFIDGLAAI 923
            L  + I  L  +
Sbjct: 1031 LTSYLIIALVCV 1042



 Score =  234 bits (573), Expect = 2e-59
 Identities = 180/599 (30%), Positives = 277/599 (46%), Gaps = 30/599 (5%)

Query: 96  SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155
           +G L+ +  +DRE +           +   V +       I +++ D NDN PQF E++ 
Sbjct: 77  TGELIVQERIDREALCEKKASCVLKQEL--VLENPLELHRISIHVQDINDNSPQFKEESI 134

Query: 156 TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG-----DVS 210
            + + E  S          +A DAD+G N+   Y +   N   + ++++ S      ++ 
Sbjct: 135 KLEIRE--SAVKGARFLLGEAHDADIGQNTVQGYTL-QQNDHFKLNVNTKSSNRKYCELL 191

Query: 211 LVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENV 270
           L K LD E  +  +L++ A DGGSP RS T  + + + D NDNAP F  S+++ S+ EN 
Sbjct: 192 LDKELDREDKQELQLLLTAVDGGSPQRSGTVVIHVTVLDANDNAPVFSQSVYKTSLPENS 251

Query: 271 PIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA 330
           P+   ++ V A DADEGVN+E+TY         NV L   +D ++G V  +G +D E   
Sbjct: 252 PLDTLVITVSAADADEGVNSEITYGFDHVLEDENVFL---LDTKTGVVRVNGAIDYEKIP 308

Query: 331 KYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTA 390
            Y++ ++A DG      A AT                       + E+  PG+ V  +  
Sbjct: 309 SYEMQISAKDG--LGLVAYATLIIEITDVNDNAPVIHLKSLTNPIPENVSPGSEVGIINV 366

Query: 391 TDADEDNRLHYEIT-GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG- 448
            D D +N      +   N   +   + +N   L+T  Q LD +    Y +T+SATD G  
Sbjct: 367 QDRDSENNRQVRCSIQQNVPFKLVASIKNYYSLVTTGQ-LDRELVSDYNITISATDEGSP 425

Query: 449 -RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507
             S +  V +++ D N+  PVFE   Y+A V E+   G+T+  VSA D D   N  + YS
Sbjct: 426 PLSSSKSVHLSVADVNDNPPVFEEQSYSAYVSENNRAGSTLCSVSARDPDWRQNGTVIYS 485

Query: 508 -LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566
            L++E+S   V+ +     +N  TG I   +  D E +  + + V ARD G P LS    
Sbjct: 486 LLAAEVSGAPVSSY---VSVNGDTGVIHAVRSFDYEQLRSFKVHVMARDNGSPPLSSNVS 542

Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALV------GTSVSQVGATDADVGLNGRIHYEL 620
           V + V DVNDN P         N     LV      G+ VS+V A DAD G N  + Y +
Sbjct: 543 VSVFVSDVNDNPPQILYPAPEGNSFMTELVPKAAHGGSLVSKVIAVDADSGQNAWLSYHI 602

Query: 621 DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679
             +  + G F I   SG IRT + +        +L     D G P  S+T  +++ I D
Sbjct: 603 -VQSSDPGLFTIGVHSGEIRTQRDISESDSMKQNLIVAVKDNGQPSLSATCSMYLLISD 660


>UniRef50_Q4SFY8 Cluster: Chromosome 7 SCAF14601, whole genome shotgun
            sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 7
            SCAF14601, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 2270

 Score =  277 bits (680), Expect = 2e-72
 Identities = 234/757 (30%), Positives = 358/757 (47%), Gaps = 104/757 (13%)

Query: 11   INVLDCNDHSPVFEMQQYEAS----VREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            I VLD ND++P F   + +      V EG  SGT + T+ A D D G+N  V Y++    
Sbjct: 670  ITVLDENDNAPTFSHTRPDRELLLQVVEGLPSGTVLGTVTAKDPDEGENGTVHYSLSGAR 729

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
            A+                     F ++  +G L   + L   + + YT +V A D  SP 
Sbjct: 730  AER--------------------FTLNPMTGELKAASPLRWAERSEYTFMVTAADHGSP- 768

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
               LSST  + + ++    +        ++V+++         +I  +++ +    +++ 
Sbjct: 769  --GLSSTCRLQIQVLSSARS--NLKPNIFSVTMNAVEGAPPGSIIGSVRSQNHQQSSSTE 824

Query: 187  --IRYAIIGGNTQM-QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS--PSRSNTT 241
              + Y ++GG+ +   F +D L GDV LV+ LDYE+   Y L I   D     PS S+  
Sbjct: 825  GQVTYLVVGGSDRDGTFMVDRLKGDVYLVRELDYEKGSRYTLHIEVSDFSQAFPS-SHLV 883

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKD 300
            QL IN++D ND+AP F        + EN   G S+   QA D D  G N+EL Y++  + 
Sbjct: 884  QLEINVQDRNDHAPHFTEDPVTIVIPENTEPGASVYTFQAIDKDGSGPNSELIYSI--EH 941

Query: 301  YTGNVDLPITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATDGGDPP---RSATATXXXXX 356
            Y     L +++DP SG V T GQ LDRE+     L+V ATD    P   R  + T     
Sbjct: 942  YWPETHL-LSLDPVSG-VLTLGQKLDRESTPSLFLVVRATDQTVDPSQRRWGSVTARMFV 999

Query: 357  XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSI 414
                     F      V + ED+P G  ++ + A D DE  + R+ Y I  GNT GRFS+
Sbjct: 1000 TDENDNTPVFSSPS-AVSVMEDQPVGFVILYVMARDEDEGENGRVSYRIQAGNTAGRFSL 1058

Query: 415  TSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENA 472
                G   +++ + LD +++  + LT+ A D G    S + ++ + + D N+ APVF+ A
Sbjct: 1059 NPNTGS--LSILKALDREEQEVFNLTIVAEDHGIPQLSTSQVLSVRVIDVNDEAPVFQRA 1116

Query: 473  PYTASVFEDAPIGTTVLVVSATDSDVGINAQITY-----------------SLSSEISNE 515
             + A V E+   GTTVL V+A D D G N  +TY                 + + E+  E
Sbjct: 1117 EFEALVIENKGPGTTVLKVTAVDRDQGSNGHVTYGGVTEEGFVINPVTGVITTTKELDTE 1176

Query: 516  AVAHH-------DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568
            A  H+       D  F ++P TGA++T++ LDRET + Y L V A D G P+LS T  V+
Sbjct: 1177 AQDHYTLTAGDPDGDFHLHPSTGALSTSRGLDRETKAEYTLEVVASDRGSPALSTTVMVQ 1236

Query: 569  ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG 628
            + V+DVNDN P+F                         +AD  LNG+  Y L       G
Sbjct: 1237 VQVMDVNDNSPIF-------------------------NADDALNGKFLYFLSQD--AHG 1269

Query: 629  SFVIDPASGVIRTNKALDRESVATHDLKAVAID-GGTPPQSSTVIVHIKIEDINDSPPVF 687
            +F +D  +GVI T+ ALDRE  A +  +  A+D     P++++  V + + D+ND+ PVF
Sbjct: 1270 AFTVDENTGVITTSAALDREKWAAYTFQVFAVDLSPAEPRNTSAQVTVTVLDVNDNAPVF 1329

Query: 688  ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
              D L   +S        +  ++A D D G N  V Y
Sbjct: 1330 IQDPLVIEVSIRHS-QRVLATMKAEDKDFGANGSVFY 1365



 Score =  249 bits (609), Expect = 1e-63
 Identities = 186/645 (28%), Positives = 305/645 (47%), Gaps = 65/645 (10%)

Query: 92   IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151
            +   SG + TR +LDRE  + Y ++V   D  +P     S+T T H+ ++D+NDN P FS
Sbjct: 627  LSSTSGEISTRLALDREHQSSYQLVVVVQDGGTPPR---SATGTAHITVLDENDNAPTFS 683

Query: 152  ----EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
                ++   + V E +      V+  + A D D G N  + Y++ G   + +F+++ ++G
Sbjct: 684  HTRPDRELLLQVVEGLP--SGTVLGTVTAKDPDEGENGTVHYSLSGARAE-RFTLNPMTG 740

Query: 208  DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI-RDVNDNAPRFYTSLFQESV 266
            ++     L + +   Y  ++ A D GSP  S+T +L I +      N      S+   +V
Sbjct: 741  ELKAASPLRWAERSEYTFMVTAADHGSPGLSSTCRLQIQVLSSARSNLKPNIFSVTMNAV 800

Query: 267  SENVPIGYSI--VRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
             E  P G  I  VR Q +        ++TY +       + D    +D   G VY   +L
Sbjct: 801  -EGAPPGSIIGSVRSQNHQQSSSTEGQVTYLVVGGS---DRDGTFMVDRLKGDVYLVREL 856

Query: 325  DRETQAKYQLLVTATDGGDP-PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383
            D E  ++Y L +  +D     P S                  F      + + E+  PG 
Sbjct: 857  DYEKGSRYTLHIEVSDFSQAFPSSHLVQLEINVQDRNDHAPHFTEDPVTIVIPENTEPGA 916

Query: 384  PVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440
             V T  A D D    ++ L Y I          ++     G++T+ Q LD +      L 
Sbjct: 917  SVYTFQAIDKDGSGPNSELIYSIEHYWPETHL-LSLDPVSGVLTLGQKLDRESTPSLFLV 975

Query: 441  VSATD-----SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495
            V ATD     S  R  +   ++ +TD N+  PVF ++P   SV ED P+G  +L V A D
Sbjct: 976  VRATDQTVDPSQRRWGSVTARMFVTDENDNTPVF-SSPSAVSVMEDQPVGFVILYVMARD 1034

Query: 496  SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555
             D G N +++Y + +   N A      +F +NP TG+++  K LDRE    + LT+ A D
Sbjct: 1035 EDEGENGRVSYRIQA--GNTA-----GRFSLNPNTGSLSILKALDREEQEVFNLTIVAED 1087

Query: 556  GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615
             G+P LS +  + + V+DVND  PVF++  + A ++E+   GT+V +V A D D G NG 
Sbjct: 1088 HGIPQLSTSQVLSVRVIDVNDEAPVFQRAEFEALVIENKGPGTTVLKVTAVDRDQGSNGH 1147

Query: 616  IHY---------------------ELDPKDRE---------EGSFVIDPASGVIRTNKAL 645
            + Y                     ELD + ++         +G F + P++G + T++ L
Sbjct: 1148 VTYGGVTEEGFVINPVTGVITTTKELDTEAQDHYTLTAGDPDGDFHLHPSTGALSTSRGL 1207

Query: 646  DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690
            DRE+ A + L+ VA D G+P  S+TV+V +++ D+ND+ P+F +D
Sbjct: 1208 DRETKAEYTLEVVASDRGSPALSTTVMVQVQVMDVNDNSPIFNAD 1252



 Score =  223 bits (545), Expect = 6e-56
 Identities = 174/575 (30%), Positives = 271/575 (47%), Gaps = 42/575 (7%)

Query: 202  IDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF-YTS 260
            + S SG++S    LD E   SY+LV+  QDGG+P RS T    I + D NDNAP F +T 
Sbjct: 627  LSSTSGEISTRLALDREHQSSYQLVVVVQDGGTPPRSATGTAHITVLDENDNAPTFSHTR 686

Query: 261  LFQE---SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317
              +E    V E +P G  +  V A D DEG N  + Y+++     G      T++P +G 
Sbjct: 687  PDRELLLQVVEGLPSGTVLGTVTAKDPDEGENGTVHYSLS-----GARAERFTLNPMTGE 741

Query: 318  VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL-- 375
            +  +  L    +++Y  +VTA D G P  S+T                  P  + V +  
Sbjct: 742  LKAASPLRWAERSEYTFMVTAADHGSPGLSSTCRLQIQVLSSARSN--LKPNIFSVTMNA 799

Query: 376  AEDEPPGTPVVTLTATDADE----DNRLHYEITGGNTR-GRFSITSQNGRGLITVAQPLD 430
             E  PPG+ + ++ + +  +    + ++ Y + GG+ R G F +    G   + + + LD
Sbjct: 800  VEGAPPGSIIGSVRSQNHQQSSSTEGQVTYLVVGGSDRDGTFMVDRLKGD--VYLVRELD 857

Query: 431  FKQERRYVLTVSATDSGGR---SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
            +++  RY L +  +D       S    ++IN+ D N++AP F   P T  + E+   G +
Sbjct: 858  YEKGSRYTLHIEVSDFSQAFPSSHLVQLEINVQDRNDHAPHFTEDPVTIVIPENTEPGAS 917

Query: 488  VLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
            V    A D D  G N+++ YS+      E          ++P +G +T  + LDRE+   
Sbjct: 918  VYTFQAIDKDGSGPNSELIYSI------EHYWPETHLLSLDPVSGVLTLGQKLDRESTPS 971

Query: 547  YLLTVTARDGGV-PSLS--DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
              L V A D  V PS     +    + V D NDN PVF       ++MED  VG  +  V
Sbjct: 972  LFLVVRATDQTVDPSQRRWGSVTARMFVTDENDNTPVFSSPS-AVSVMEDQPVGFVILYV 1030

Query: 604  GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
             A D D G NGR+ Y +   +   G F ++P +G +   KALDRE     +L  VA D G
Sbjct: 1031 MARDEDEGENGRVSYRIQAGNTA-GRFSLNPNTGSLSILKALDREEQEVFNLTIVAEDHG 1089

Query: 664  TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
             P  S++ ++ +++ D+ND  PVF+       + EN   GTT+ ++ A D D+G N  V 
Sbjct: 1090 IPQLSTSQVLSVRVIDVNDEAPVFQRAEFEALVIENKGPGTTVLKVTAVDRDQGSNGHVT 1149

Query: 724  YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758
            Y   GG     F +    G     + T  +LD E+
Sbjct: 1150 Y---GGVTEEGFVINPVTG----VITTTKELDTEA 1177



 Score =  214 bits (523), Expect = 3e-53
 Identities = 181/594 (30%), Positives = 278/594 (46%), Gaps = 41/594 (6%)

Query: 276 IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA-KYQL 334
           + +V A D D G    +TY +         D   TID  SG + TS  LDR+  A K+ L
Sbjct: 19  LAQVSATDEDRGSFGAVTYALGSPSGNTPPD-QFTIDKGSGQLCTSTPLDRDEGADKFDL 77

Query: 335 LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394
            VTATDGG    S+ A               F P  Y V L+    PGT VV +TA D D
Sbjct: 78  TVTATDGGG--LSSVARVRVSVVDINDNRPAFYPVLYTVSLSTHSSPGTSVVKVTANDPD 135

Query: 395 E--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSD- 451
              + R+ Y    G     F++    G  +I++++ L  K      + ++A D GG +  
Sbjct: 136 SGLNGRVTYRTVPGGGSAFFTLNKDTG--VISLSRSLHGKANTVISMEIAAEDGGGLTAP 193

Query: 452 -TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510
             A V +++   +  +PVFE A Y  +V ED   GT++ VV A+ +  G +  I YS+SS
Sbjct: 194 VNARVNVSVVGGSVTSPVFEQAQYFFTVPEDVLRGTSLGVVRAS-AKTGGSKDILYSISS 252

Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570
               +   +    F ++  TG I T   LD ET S   L + AR G  P+   TT V I+
Sbjct: 253 ---GDPYGY----FTVDSSTGTIRTALPLDHETCSSLELEIQARYGFPPAYG-TTRVRIT 304

Query: 571 VVDVNDNEPVFKQQLYTANIM-EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629
           + D+NDN P F      + ++ E   +GT +  + ATD D G NG++ ++L        S
Sbjct: 305 ISDINDNAPAFLPSSSESLLLPEITKMGTVIYTIQATDRDSGHNGQLSFDLVSAGAAGSS 364

Query: 630 ----FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS--TVIVHIKIEDINDS 683
               F +D  SG +R   +L  ESV  +DL+ VA DGG P  SS  T++VHI+ +D    
Sbjct: 365 GQRTFGVDRGSGEVRLIGSLSYESVPRYDLQVVAKDGGAPQLSSTFTLVVHIQAQDARG- 423

Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
            P F++      + EN+P+ T   ++RA + +    + + Y ++   D+  F +     S
Sbjct: 424 -PNFDTLTYRVELRENTPLNTQFLQVRALNTEASGGSSISYHLRPDGDAAGFGIM----S 478

Query: 744 DKAELVTMVDLDYESPRKKYELVIRAASPP----LWNDVRVEILVTDVNDNAPVMKDFQI 799
           D   +     LD E  +  Y L + A+S P          V + VTD NDN+P +   ++
Sbjct: 479 DSGWIFVRSSLDRE-VKDMYLLTVLASSGPGGAGRTGSATVRVTVTDENDNSPRLSQERV 537

Query: 800 IFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTL 851
                ++      FGRV A D D  +  +L Y++L  +      +N  TG + +
Sbjct: 538 FLAVRENLLAGTGFGRVSAIDRDAGLNARLTYKLL--HTDRHFQINSQTGKIII 589



 Score =  204 bits (498), Expect = 3e-50
 Identities = 165/588 (28%), Positives = 265/588 (45%), Gaps = 21/588 (3%)

Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAI--IGGNTQM-QFSIDSLSGDVSLVKTLDYEQ 219
           IS T   ++A++ ATD D G+  A+ YA+    GNT   QF+ID  SG +     LD ++
Sbjct: 11  ISDTRVSMLAQVSATDEDRGSFGAVTYALGSPSGNTPPDQFTIDKGSGQLCTSTPLDRDE 70

Query: 220 -VRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR 278
               + L + A DGG    S+  ++ +++ D+NDN P FY  L+  S+S +   G S+V+
Sbjct: 71  GADKFDLTVTATDGGG--LSSVARVRVSVVDINDNRPAFYPVLYTVSLSTHSSPGTSVVK 128

Query: 279 VQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA 338
           V A D D G+N  +TY    +   G      T++  +G +  S  L  +      + + A
Sbjct: 129 VTANDPDSGLNGRVTY----RTVPGGGSAFFTLNKDTGVISLSRSLHGKANTVISMEIAA 184

Query: 339 TDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR 398
            DGG       A               F   QY   + ED   GT +  + A+     ++
Sbjct: 185 EDGGGLTAPVNARVNVSVVGGSVTSPVFEQAQYFFTVPEDVLRGTSLGVVRASAKTGGSK 244

Query: 399 -LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS-DTAMVQ 456
            + Y I+ G+  G F++ S    G I  A PLD +      L + A      +  T  V+
Sbjct: 245 DILYSISSGDPYGYFTVDSST--GTIRTALPLDHETCSSLELEIQARYGFPPAYGTTRVR 302

Query: 457 INITDANNYAPVF-ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515
           I I+D N+ AP F  ++  +  + E   +GT +  + ATD D G N Q+++ L S  +  
Sbjct: 303 ITISDINDNAPAFLPSSSESLLLPEITKMGTVIYTIQATDRDSGHNGQLSFDLVS--AGA 360

Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575
           A +   + F ++  +G +     L  E++  Y L V A+DGG P LS T  + + +   +
Sbjct: 361 AGSSGQRTFGVDRGSGEVRLIGSLSYESVPRYDLQVVAKDGGAPQLSSTFTLVVHIQAQD 420

Query: 576 DNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA 635
              P F    Y   + E+  + T   QV A + +      I Y L P D +   F I   
Sbjct: 421 ARGPNFDTLTYRVELRENTPLNTQFLQVRALNTEASGGSSISYHLRP-DGDAAGFGIMSD 479

Query: 636 SGVIRTNKALDRESVATHDLKAVAIDG-GTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694
           SG I    +LDRE    + L  +A  G G   ++ +  V + + D ND+ P    + +  
Sbjct: 480 SGWIFVRSSLDREVKDMYLLTVLASSGPGGAGRTGSATVRVTVTDENDNSPRLSQERVFL 539

Query: 695 YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
            + EN   GT  G + A D D G NA + Y +   D    F + ++ G
Sbjct: 540 AVRENLLAGTGFGRVSAIDRDAGLNARLTYKLLHTD--RHFQINSQTG 585



 Score =  195 bits (475), Expect = 2e-47
 Identities = 175/629 (27%), Positives = 283/629 (44%), Gaps = 37/629 (5%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATD--QASPVSDRLSSTATIHVNIIDDNDNY 147
            F +D   G +     LD EK +RYT+ ++ +D  QA P S  +     + +N+ D ND+ 
Sbjct: 841  FMVDRLKGDVYLVRELDYEKGSRYTLHIEVSDFSQAFPSSHLVQ----LEINVQDRNDHA 896

Query: 148  PQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSAIRYAI--IGGNTQMQFSIDS 204
            P F+E   T+ + E+        +   +A D D  G NS + Y+I      T +  S+D 
Sbjct: 897  PHFTEDPVTIVIPENTE--PGASVYTFQAIDKDGSGPNSELIYSIEHYWPETHL-LSLDP 953

Query: 205  LSGDVSLVKTLDYEQVRSYRLVIRAQD---GGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261
            +SG ++L + LD E   S  LV+RA D     S  R  +    + + D NDN P F +S 
Sbjct: 954  VSGVLTLGQKLDRESTPSLFLVVRATDQTVDPSQRRWGSVTARMFVTDENDNTPVF-SSP 1012

Query: 262  FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321
               SV E+ P+G+ I+ V A D DEG N  ++Y +      GN     +++P +G +   
Sbjct: 1013 SAVSVMEDQPVGFVILYVMARDEDEGENGRVSYRIQ----AGNTAGRFSLNPNTGSLSIL 1068

Query: 322  GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381
              LDRE Q  + L + A D G P  S +                F   ++E  + E++ P
Sbjct: 1069 KALDREEQEVFNLTIVAEDHGIPQLSTSQVLSVRVIDVNDEAPVFQRAEFEALVIENKGP 1128

Query: 382  GTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441
            GT V+ +TA D D+ +  H    GG T   F I    G  +IT  + LD + +  Y LT 
Sbjct: 1129 GTTVLKVTAVDRDQGSNGHVTY-GGVTEEGFVINPVTG--VITTTKELDTEAQDHYTLTA 1185

Query: 442  SATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501
               D       +   ++ +   +     E      +    +P  +T ++V     DV  N
Sbjct: 1186 GDPDGDFHLHPSTGALSTSRGLDRETKAEYTLEVVASDRGSPALSTTVMVQVQVMDVNDN 1245

Query: 502  AQITYSLSSEISNEAVAHHDQQ----FVINPQTGAITTNKLLDRETMSGYLLTVTARDGG 557
            + I ++    ++ + +    Q     F ++  TG ITT+  LDRE  + Y   V A D  
Sbjct: 1246 SPI-FNADDALNGKFLYFLSQDAHGAFTVDENTGVITTSAALDREKWAAYTFQVFAVDLS 1304

Query: 558  VPSLSDTT-DVEISVVDVNDNEPVFKQQ--LYTANIMEDALVGTSVSQVGATDADVGLNG 614
                 +T+  V ++V+DVNDN PVF Q   +   +I     V   ++ + A D D G NG
Sbjct: 1305 PAEPRNTSAQVTVTVLDVNDNAPVFIQDPLVIEVSIRHSQRV---LATMKAEDKDFGANG 1361

Query: 615  RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674
             + Y      +    F I+  +G I+  + L   + A   L   A+D G+P QS+  +V 
Sbjct: 1362 SVFYRFATPVK---GFSINSLTGEIQATEPLQDLTQAQRTLIVEAMDQGSPAQSAQGVVV 1418

Query: 675  IKIEDINDSPPVFESDCLTFYISENSPIG 703
            I ++++  +   F  +     I EN+  G
Sbjct: 1419 IYVKEVVYNGIRFSRNARDVSIQENAAKG 1447



 Score =  194 bits (474), Expect = 2e-47
 Identities = 171/608 (28%), Positives = 258/608 (42%), Gaps = 50/608 (8%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELV 65
            +  +INV D NDH+P F        + E    G +V T +A D+D  G N+E+ Y+IE  
Sbjct: 883  VQLEINVQDRNDHAPHFTEDPVTIVIPENTEPGASVYTFQAIDKDGSGPNSELIYSIEHY 942

Query: 66   TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125
              +T                   +  +D  SG L     LDRE      ++V+ATDQ   
Sbjct: 943  WPET------------------HLLSLDPVSGVLTLGQKLDRESTPSLFLVVRATDQTVD 984

Query: 126  VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
             S R   + T  + + D+NDN P FS  +  VSV ED  V    VI  + A D D G N 
Sbjct: 985  PSQRRWGSVTARMFVTDENDNTPVFSSPS-AVSVMEDQPV--GFVILYVMARDEDEGENG 1041

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
             + Y I  GNT  +FS++  +G +S++K LD E+   + L I A+D G P  S +  L +
Sbjct: 1042 RVSYRIQAGNTAGRFSLNPNTGSLSILKALDREEQEVFNLTIVAEDHGIPQLSTSQVLSV 1101

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
             + DVND AP F  + F+  V EN   G ++++V A D D+G N  +T       Y G  
Sbjct: 1102 RVIDVNDEAPVFQRAEFEALVIENKGPGTTVLKVTAVDRDQGSNGHVT-------YGGVT 1154

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
            +    I+P +G + T+ +LD E Q  Y L     DG      +T                
Sbjct: 1155 EEGFVINPVTGVITTTKELDTEAQDHYTLTAGDPDGDFHLHPSTGALSTSRGLDRETKAE 1214

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRF--------SITSQ 417
            +       +        T +V +   D ++++ +       N +  +        + T  
Sbjct: 1215 YTLEVVASDRGSPALSTTVMVQVQVMDVNDNSPIFNADDALNGKFLYFLSQDAHGAFTVD 1274

Query: 418  NGRGLITVAQPLDFKQERRYVLTVSATD---SGGRSDTAMVQINITDANNYAPVFENAPY 474
               G+IT +  LD ++   Y   V A D   +  R+ +A V + + D N+ APVF   P 
Sbjct: 1275 ENTGVITTSAALDREKWAAYTFQVFAVDLSPAEPRNTSAQVTVTVLDVNDNAPVFIQDPL 1334

Query: 475  TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
               V         +  + A D D G N  + Y  ++ +           F IN  TG I 
Sbjct: 1335 VIEV-SIRHSQRVLATMKAEDKDFGANGSVFYRFATPVKG---------FSINSLTGEIQ 1384

Query: 535  TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
              + L   T +   L V A D G P+ S    V I V +V  N   F +     +I E+A
Sbjct: 1385 ATEPLQDLTQAQRTLIVEAMDQGSPAQSAQGVVVIYVKEVVYNGIRFSRNARDVSIQENA 1444

Query: 595  LVGTSVSQ 602
              G  + Q
Sbjct: 1445 AKGEIMVQ 1452



 Score =  194 bits (473), Expect = 3e-47
 Identities = 162/562 (28%), Positives = 257/562 (45%), Gaps = 33/562 (5%)

Query: 88  DVFRIDGRSGALLTRASLDREKVA-RYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146
           D F ID  SG L T   LDR++ A ++ + V ATD        LSS A + V+++D NDN
Sbjct: 49  DQFTIDKGSGQLCTSTPLDRDEGADKFDLTVTATDGGG-----LSSVARVRVSVVDINDN 103

Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206
            P F    YTVS+    S      + K+ A D D G N  + Y  + G     F+++  +
Sbjct: 104 RPAFYPVLYTVSLSTHSS--PGTSVVKVTANDPDSGLNGRVTYRTVPGGGSAFFTLNKDT 161

Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266
           G +SL ++L  +      + I A+DGG  +     ++ +++   +  +P F  + +  +V
Sbjct: 162 GVISLSRSLHGKANTVISMEIAAEDGGGLTAPVNARVNVSVVGGSVTSPVFEQAQYFFTV 221

Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326
            E+V  G S+  V+A  A  G + ++ Y+++  D  G      T+D  +G + T+  LD 
Sbjct: 222 PEDVLRGTSLGVVRA-SAKTGGSKDILYSISSGDPYGY----FTVDSSTGTIRTALPLDH 276

Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE-VELAEDEPPGTPV 385
           ET +  +L + A   G PP   T                F+P   E + L E    GT +
Sbjct: 277 ETCSSLELEIQAR-YGFPPAYGTTRVRITISDINDNAPAFLPSSSESLLLPEITKMGTVI 335

Query: 386 VTLTATDAD--EDNRLHYEIT---GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440
            T+ ATD D   + +L +++       + G+ +     G G + +   L ++   RY L 
Sbjct: 336 YTIQATDRDSGHNGQLSFDLVSAGAAGSSGQRTFGVDRGSGEVRLIGSLSYESVPRYDLQ 395

Query: 441 VSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498
           V A D G    S T  + ++I   +   P F+   Y   + E+ P+ T  L V A +++ 
Sbjct: 396 VVAKDGGAPQLSSTFTLVVHIQAQDARGPNFDTLTYRVELRENTPLNTQFLQVRALNTEA 455

Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG-G 557
              + I+Y L  +   +A       F I   +G I     LDRE    YLLTV A  G G
Sbjct: 456 SGGSSISYHLRPD--GDAAG-----FGIMSDSGWIFVRSSLDREVKDMYLLTVLASSGPG 508

Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617
               + +  V ++V D NDN P   Q+     + E+ L GT   +V A D D GLN R+ 
Sbjct: 509 GAGRTGSATVRVTVTDENDNSPRLSQERVFLAVRENLLAGTGFGRVSAIDRDAGLNARLT 568

Query: 618 YELDPKDREEGSFVIDPASGVI 639
           Y+L   DR    F I+  +G I
Sbjct: 569 YKLLHTDRH---FQINSQTGKI 587



 Score =  184 bits (449), Expect = 2e-44
 Identities = 176/588 (29%), Positives = 258/588 (43%), Gaps = 46/588 (7%)

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
            + +   SG + T   LDRE Q+ YQL+V   DGG PPRSAT T              F  
Sbjct: 625  LCLSSTSGEISTRLALDREHQSSYQLVVVVQDGGTPPRSATGTAHITVLDENDNAPTFSH 684

Query: 369  GQYEVEL----AEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGL 422
             + + EL     E  P GT + T+TA D D  E+  +HY ++G     RF++    G   
Sbjct: 685  TRPDRELLLQVVEGLPSGTVLGTVTAKDPDEGENGTVHYSLSGARAE-RFTLNPMTGE-- 741

Query: 423  ITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDA--NNYAP-VFENAPYTAS 477
            +  A PL + +   Y   V+A D G  G S T  +QI +  +  +N  P +F     T +
Sbjct: 742  LKAASPLRWAERSEYTFMVTAADHGSPGLSSTCRLQIQVLSSARSNLKPNIFS---VTMN 798

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ--FVINPQTGAITT 535
              E AP G+   ++ +  S    N Q + S   +++   V   D+   F+++   G +  
Sbjct: 799  AVEGAPPGS---IIGSVRSQ---NHQQSSSTEGQVTYLVVGGSDRDGTFMVDRLKGDVYL 852

Query: 536  NKLLDRETMSGYLLTVTARD--GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593
             + LD E  S Y L +   D     PS S    +EI+V D ND+ P F +   T  I E+
Sbjct: 853  VRELDYEKGSRYTLHIEVSDFSQAFPS-SHLVQLEINVQDRNDHAPHFTEDPVTIVIPEN 911

Query: 594  ALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652
               G SV    A D D  G N  + Y ++    E     +DP SGV+   + LDRES  +
Sbjct: 912  TEPGASVYTFQAIDKDGSGPNSELIYSIEHYWPETHLLSLDPVSGVLTLGQKLDRESTPS 971

Query: 653  HDLKAVAIDGGTPPQS---STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
              L   A D    P      +V   + + D ND+ PVF S      + E+ P+G  I  +
Sbjct: 972  LFLVVRATDQTVDPSQRRWGSVTARMFVTDENDNTPVFSSPS-AVSVMEDQPVGFVILYV 1030

Query: 710  RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
             A D DEG N  V Y I+ G+ +  FSL    GS    L  +  LD E  ++ + L I A
Sbjct: 1031 MARDEDEGENGRVSYRIQAGNTAGRFSLNPNTGS----LSILKALDREE-QEVFNLTIVA 1085

Query: 770  AS---PPLWNDVRVEILVTDVNDNAPVMK--DFQIIFNNYKDCFPVGPFGRVPAYDADVT 824
                 P L     + + V DVND APV +  +F+ +    K   P     +V A D D  
Sbjct: 1086 EDHGIPQLSTSQVLSVRVIDVNDEAPVFQRAEFEALVIENKG--PGTTVLKVTAVDRDQG 1143

Query: 825  DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
                +    G      ++N  TG +T + +L+T      T+     DG
Sbjct: 1144 SN-GHVTYGGVTEEGFVINPVTGVITTTKELDTEAQDHYTLTAGDPDG 1190



 Score =  175 bits (425), Expect = 2e-41
 Identities = 155/534 (29%), Positives = 239/534 (44%), Gaps = 50/534 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +++V+D ND+ P F    Y  S+   +S GT+V+ + A D D G N  V Y         
Sbjct: 94  RVSVVDINDNRPAFYPVLYTVSLSTHSSPGTSVVKVTANDPDSGLNGRVTYRTV------ 147

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD---QASPV 126
             P                 F ++  +G +    SL  +     ++ + A D     +PV
Sbjct: 148 --PGGGSA-----------FFTLNKDTGVISLSRSLHGKANTVISMEIAAEDGGGLTAPV 194

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
           + R+      +V+++  +   P F +  Y  +V ED  V     +  ++A+ A  G +  
Sbjct: 195 NARV------NVSVVGGSVTSPVFEQAQYFFTVPED--VLRGTSLGVVRAS-AKTGGSKD 245

Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           I Y+I  G+    F++DS +G +     LD+E   S  L I+A+ G  P+   TT++ I 
Sbjct: 246 ILYSISSGDPYGYFTVDSSTGTIRTALPLDHETCSSLELEIQARYGFPPA-YGTTRVRIT 304

Query: 247 IRDVNDNAPRFYTSLFQE-SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
           I D+NDNAP F  S  +   + E   +G  I  +QA D D G N +L++ +      G+ 
Sbjct: 305 ISDINDNAPAFLPSSSESLLLPEITKMGTVIYTIQATDRDSGHNGQLSFDLVSAGAAGSS 364

Query: 306 -DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
                 +D  SG V   G L  E+  +Y L V A DGG P  S+T T             
Sbjct: 365 GQRTFGVDRGSGEVRLIGSLSYESVPRYDLQVVAKDGGAPQLSSTFTLVVHIQAQDARGP 424

Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTA--TDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422
            F    Y VEL E+ P  T  + + A  T+A   + + Y +        F I S +  G 
Sbjct: 425 NFDTLTYRVELRENTPLNTQFLQVRALNTEASGGSSISYHLRPDGDAAGFGIMSDS--GW 482

Query: 423 ITVAQPLDFKQERRYVLTVSATD---SGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479
           I V   LD + +  Y+LTV A+      GR+ +A V++ +TD N+ +P         +V 
Sbjct: 483 IFVRSSLDREVKDMYLLTVLASSGPGGAGRTGSATVRVTVTDENDNSPRLSQERVFLAVR 542

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
           E+   GT    VSA D D G+NA++TY L          H D+ F IN QTG I
Sbjct: 543 ENLLAGTGFGRVSAIDRDAGLNARLTYKL---------LHTDRHFQINSQTGKI 587



 Score =  157 bits (382), Expect = 3e-36
 Identities = 127/412 (30%), Positives = 197/412 (47%), Gaps = 23/412 (5%)

Query: 372 EVELAEDEPPGTPVVTLTATDADEDN--RLHYEI--TGGNTRGRFSITSQNGRGLITVAQ 427
           E  LA  +   + +  ++ATD D  +   + Y +    GNT      T   G G +  + 
Sbjct: 6   EPVLAISDTRVSMLAQVSATDEDRGSFGAVTYALGSPSGNTPPD-QFTIDKGSGQLCTST 64

Query: 428 PLDFKQER-RYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
           PLD  +   ++ LTV+ATD GG S  A V++++ D N+  P F    YT S+   +  GT
Sbjct: 65  PLDRDEGADKFDLTVTATDGGGLSSVARVRVSVVDINDNRPAFYPVLYTVSLSTHSSPGT 124

Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
           +V+ V+A D D G+N ++TY     +     A     F +N  TG I+ ++ L  +  + 
Sbjct: 125 SVVKVTANDPDSGLNGRVTY---RTVPGGGSAF----FTLNKDTGVISLSRSLHGKANTV 177

Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
             + + A DGG  +      V +SVV  +   PVF+Q  Y   + ED L GTS+  V A+
Sbjct: 178 ISMEIAAEDGGGLTAPVNARVNVSVVGGSVTSPVFEQAQYFFTVPEDVLRGTSLGVVRAS 237

Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
            A  G +  I Y +   D   G F +D ++G IRT   LD E+ ++ +L+ +    G PP
Sbjct: 238 -AKTGGSKDILYSISSGD-PYGYFTVDSSTGTIRTALPLDHETCSSLELE-IQARYGFPP 294

Query: 667 QSSTVIVHIKIEDINDSPPVF-ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
              T  V I I DIND+ P F  S   +  + E + +GT I  I+A D D G N  + + 
Sbjct: 295 AYGTTRVRITISDINDNAPAFLPSSSESLLLPEITKMGTVIYTIQATDRDSGHNGQLSFD 354

Query: 726 IKGGDDSNSFSLET---RQGSDKAELVTMVDLDYES-PRKKYELVIRAASPP 773
           +     + S    T    +GS +  L+    L YES PR   ++V +    P
Sbjct: 355 LVSAGAAGSSGQRTFGVDRGSGEVRLIG--SLSYESVPRYDLQVVAKDGGAP 404



 Score =  128 bits (309), Expect = 2e-27
 Identities = 115/450 (25%), Positives = 199/450 (44%), Gaps = 41/450 (9%)

Query: 1   MSVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEY 60
           ++ P      ++V+  +  SPVFE  QY  +V E    GT++  ++A+ +  G + ++ Y
Sbjct: 190 LTAPVNARVNVSVVGGSVTSPVFEQAQYFFTVPEDVLRGTSLGVVRASAKT-GGSKDILY 248

Query: 61  TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT 120
           +I   + D                     F +D  +G + T   LD E  +   + ++A 
Sbjct: 249 SIS--SGDPYG-----------------YFTVDSSTGTIRTALPLDHETCSSLELEIQAR 289

Query: 121 DQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD 180
               P       T  + + I D NDN P F   +    +  +I+     VI  I+ATD D
Sbjct: 290 YGFPPAY----GTTRVRITISDINDNAPAFLPSSSESLLLPEITKMGT-VIYTIQATDRD 344

Query: 181 VGANSAIRYAII-----GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP 235
            G N  + + ++     G + Q  F +D  SG+V L+ +L YE V  Y L + A+DGG+P
Sbjct: 345 SGHNGQLSFDLVSAGAAGSSGQRTFGVDRGSGEVRLIGSLSYESVPRYDLQVVAKDGGAP 404

Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295
             S+T  L+++I+  +   P F T  ++  + EN P+    ++V+A + +    + ++Y 
Sbjct: 405 QLSSTFTLVVHIQAQDARGPNFDTLTYRVELRENTPLNTQFLQVRALNTEASGGSSISYH 464

Query: 296 M-TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG-GDPPRSATATXX 353
           +  D D  G       I   SGW++    LDRE +  Y L V A+ G G   R+ +AT  
Sbjct: 465 LRPDGDAAG-----FGIMSDSGWIFVRSSLDREVKDMYLLTVLASSGPGGAGRTGSATVR 519

Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGR 411
                           +  + + E+   GT    ++A D D   + RL Y++   +T   
Sbjct: 520 VTVTDENDNSPRLSQERVFLAVRENLLAGTGFGRVSAIDRDAGLNARLTYKLL--HTDRH 577

Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTV 441
           F I SQ G+ +I +    +     R  L +
Sbjct: 578 FQINSQTGKIIIPITDIKELHSSIRVQLLI 607



 Score =  115 bits (276), Expect = 2e-23
 Identities = 81/251 (32%), Positives = 133/251 (52%), Gaps = 12/251 (4%)

Query: 481  DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
            D  IGT + +V  T +DV  +  ++YSL  + +   +    +    N  +GA+   + LD
Sbjct: 1567 DMLIGTEITLV--TGNDVDSSPALSYSLQLDPTALGMFGIHRY---NQWSGALRLQRALD 1621

Query: 541  RETMSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
            RE  S + + + A DG G  +L+    V + V DVNDN P F  ++ TA+I E+    ++
Sbjct: 1622 REHQSTHTVIIQATDGQGHFALAP---VVVEVKDVNDNHPFFPVEVLTASIRENQPANSA 1678

Query: 600  VSQVGATDADVGLNGRIHY-ELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
            V+ + A D D G+ G + Y  L+     + SF +DP SG IR+    D E + + +  A+
Sbjct: 1679 VTVLHAIDHDTGVFGHLKYFMLERTGTGKESFSVDPNSGEIRSKIPFDFEKINSFNFVAM 1738

Query: 659  AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
            AID G    S+TV V + +   ++  PVF S   +F + E +  G +IG+++A+D D G 
Sbjct: 1739 AIDSGN--HSATVTVQVFVTGEDEYDPVFLSQDFSFEVPEGAKKGQSIGQVQANDEDGGV 1796

Query: 719  NAVVHYSIKGG 729
            + +V YS   G
Sbjct: 1797 DGIVLYSFPTG 1807



 Score = 94.7 bits (225), Expect = 3e-17
 Identities = 65/209 (31%), Positives = 104/209 (49%), Gaps = 11/209 (5%)

Query: 89   VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
            + R +  SGAL  + +LDRE  + +TV+++ATD          + A + V + D NDN+P
Sbjct: 1604 IHRYNQWSGALRLQRALDREHQSTHTVIIQATDGQGHF-----ALAPVVVEVKDVNDNHP 1658

Query: 149  QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII--GGNTQMQFSIDSLS 206
             F  +  T S+ E+     N  +  + A D D G    ++Y ++   G  +  FS+D  S
Sbjct: 1659 FFPVEVLTASIRENQPA--NSAVTVLHAIDHDTGVFGHLKYFMLERTGTGKESFSVDPNS 1716

Query: 207  GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266
            G++      D+E++ S+  V  A D G+ S + T Q+ +   D  D  P F +  F   V
Sbjct: 1717 GEIRSKIPFDFEKINSFNFVAMAIDSGNHSATVTVQVFVTGEDEYD--PVFLSQDFSFEV 1774

Query: 267  SENVPIGYSIVRVQAYDADEGVNAELTYT 295
             E    G SI +VQA D D GV+  + Y+
Sbjct: 1775 PEGAKKGQSIGQVQANDEDGGVDGIVLYS 1803



 Score = 79.8 bits (188), Expect = 1e-12
 Identities = 59/222 (26%), Positives = 97/222 (43%), Gaps = 10/222 (4%)

Query: 177  TDADVGANSAIRYAIIGGNTQM-QFSI---DSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232
            T  DV ++ A+ Y++    T +  F I   +  SG + L + LD E   ++ ++I+A DG
Sbjct: 1578 TGNDVDSSPALSYSLQLDPTALGMFGIHRYNQWSGALRLQRALDREHQSTHTVIIQATDG 1637

Query: 233  GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292
                      +++ ++DVNDN P F   +   S+ EN P   ++  + A D D GV   L
Sbjct: 1638 --QGHFALAPVVVEVKDVNDNHPFFPVEVLTASIRENQPANSAVTVLHAIDHDTGVFGHL 1695

Query: 293  TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352
             Y M ++  TG      ++DP SG + +    D E    +  +  A D G+   SAT T 
Sbjct: 1696 KYFMLERTGTGKES--FSVDPNSGEIRSKIPFDFEKINSFNFVAMAIDSGN--HSATVTV 1751

Query: 353  XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394
                         F+   +  E+ E    G  +  + A D D
Sbjct: 1752 QVFVTGEDEYDPVFLSQDFSFEVPEGAKKGQSIGQVQANDED 1793



 Score = 77.8 bits (183), Expect = 4e-12
 Identities = 124/521 (23%), Positives = 198/521 (38%), Gaps = 58/521 (11%)

Query: 11   INVLDCNDHSPVFEMQQY--EASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68
            + VLD ND++PVF       E S+R    S   + T+KA D+D G N  V Y        
Sbjct: 1317 VTVLDVNDNAPVFIQDPLVIEVSIRH---SQRVLATMKAEDKDFGANGSVFYRFATPVKG 1373

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
                                 F I+  +G +     L     A+ T++V+A DQ SP   
Sbjct: 1374 ---------------------FSINSLTGEIQATEPLQDLTQAQRTLIVEAMDQGSPAQ- 1411

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-------- 180
              S+   + + + +   N  +FS     VS+ E+ +     ++   K  D +        
Sbjct: 1412 --SAQGVVVIYVKEVVYNGIRFSRNARDVSIQEN-AAKGEIMVQSSKGLDFEDTPRLRLV 1468

Query: 181  VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDY-EQVRSYRLVIR---AQDGGSPS 236
            V A S    + +  N  +Q   D+L     L   + Y  + + Y + I    A+D     
Sbjct: 1469 VKAESVSSTSFMAINLILQDVNDNLPR-FQLQNYIAYMREAQGYDMPIIQVVAEDVDQGQ 1527

Query: 237  RSNTTQLLINIRDVNDNAPRFY-------TSLFQESVSENVPIGYSIVRVQAYDADEGVN 289
                 ++  +      NA  F+       T  F      ++ IG  I  V   D D   +
Sbjct: 1528 NGQEVRIPESNYISCQNAHSFFCFLKFYLTCFFVFFFPLDMLIGTEITLVTGNDVDS--S 1585

Query: 290  AELTYTMT-DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348
              L+Y++  D    G   +    +  SG +     LDRE Q+ + +++ ATDG      A
Sbjct: 1586 PALSYSLQLDPTALGMFGIH-RYNQWSGALRLQRALDREHQSTHTVIIQATDGQG--HFA 1642

Query: 349  TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGG 406
             A               F        + E++P  + V  L A D D      L Y +   
Sbjct: 1643 LAPVVVEVKDVNDNHPFFPVEVLTASIRENQPANSAVTVLHAIDHDTGVFGHLKYFMLER 1702

Query: 407  NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYA 466
               G+ S +     G I    P DF++   +     A DSG  S T  VQ+ +T  + Y 
Sbjct: 1703 TGTGKESFSVDPNSGEIRSKIPFDFEKINSFNFVAMAIDSGNHSATVTVQVFVTGEDEYD 1762

Query: 467  PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507
            PVF +  ++  V E A  G ++  V A D D G++  + YS
Sbjct: 1763 PVFLSQDFSFEVPEGAKKGQSIGQVQANDEDGGVDGIVLYS 1803



 Score = 59.7 bits (138), Expect = 1e-06
 Identities = 43/170 (25%), Positives = 73/170 (42%), Gaps = 4/170 (2%)

Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765
           + ++ A D D G    V Y++ G    N+   +        +L T   LD +    K++L
Sbjct: 19  LAQVSATDEDRGSFGAVTYAL-GSPSGNTPPDQFTIDKGSGQLCTSTPLDRDEGADKFDL 77

Query: 766 VIRAASPPLWNDV-RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD-- 822
            + A      + V RV + V D+NDN P         +      P     +V A D D  
Sbjct: 78  TVTATDGGGLSSVARVRVSVVDINDNRPAFYPVLYTVSLSTHSSPGTSVVKVTANDPDSG 137

Query: 823 VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
           +  ++ YR + G  +    LN+ TG ++LS  L+     + +ME++  DG
Sbjct: 138 LNGRVTYRTVPGGGSAFFTLNKDTGVISLSRSLHGKANTVISMEIAAEDG 187



 Score = 40.7 bits (91), Expect = 0.57
 Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 8/74 (10%)

Query: 723  HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVR 779
            HY++  GD    F L    G+    L T   LD E+ + +Y L + A+   SP L   V 
Sbjct: 1180 HYTLTAGDPDGDFHLHPSTGA----LSTSRGLDRET-KAEYTLEVVASDRGSPALSTTVM 1234

Query: 780  VEILVTDVNDNAPV 793
            V++ V DVNDN+P+
Sbjct: 1235 VQVQVMDVNDNSPI 1248



 Score = 37.9 bits (84), Expect = 4.0
 Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 7/85 (8%)

Query: 533  ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV--DVNDNEPVFKQQLYTANI 590
            + ++K LD E      L V A      S+S T+ + I+++  DVNDN P F+ Q Y A +
Sbjct: 1451 VQSSKGLDFEDTPRLRLVVKAE-----SVSSTSFMAINLILQDVNDNLPRFQLQNYIAYM 1505

Query: 591  MEDALVGTSVSQVGATDADVGLNGR 615
             E       + QV A D D G NG+
Sbjct: 1506 REAQGYDMPIIQVVAEDVDQGQNGQ 1530


>UniRef50_A7SN99 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 943

 Score =  276 bits (676), Expect = 7e-72
 Identities = 251/889 (28%), Positives = 397/889 (44%), Gaps = 101/889 (11%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ + D ND++PVF    Y  SV+E  + GTT   +KATD D G+NA ++Y+I       
Sbjct: 121 RVQIEDVNDNTPVFINTPYSISVKEN-TLGTTGFAVKATDADQGQNALIKYSIT------ 173

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
               +A             VF   G          LD EK   + + V A+D       R
Sbjct: 174 -GGNEANMFKIGAYEGTISVFPDSG---------VLDYEKYKSFNLTVSASDLGGVNGSR 223

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            + T+ + + + D +D    FS   YT  V E  S T    +  + A D D+  N  + Y
Sbjct: 224 TAVTS-VFIRVEDVDDLPAVFSPDYYTAKVAE--SSTKGFYVTTVTARDGDLSLNKPVSY 280

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            I  G T      + +S  +  + T+       ++ V             T Q  I I D
Sbjct: 281 FIDQGITTSPQHYEPVSSSIKAISTI-------HKAVFA-----------TVQ--ITITD 320

Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
           +NDNAP+F    +  +V EN P G +++RV A DAD G NA+ TY++T     G      
Sbjct: 321 INDNAPKFVNLPYSGTVPENSPTGLTVLRVTAQDADSGDNAKFTYSLTGA--AGKF---- 374

Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            +    G+V  SG +DRETQ  Y+  V+ +D    P +                    P 
Sbjct: 375 -VVSSEGYVVVSGNIDRETQDTYEFKVSVSDADLGPNADVRFSFIPDSSGLDKLFTIDPV 433

Query: 370 QYEVE-LA----EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG----- 419
             +++ LA    E+       + +    + +  R  Y       R R + T++ G     
Sbjct: 434 SGDIKTLATFDREERVSYGLGIRVIDQPSGQQGRYVYIANKRFIRSRDNQTTRKGDNIAN 493

Query: 420 ----RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAP-Y 474
                GL+  +  LD +    Y L V ATD GG+  T+ + + + D N+ APVF     Y
Sbjct: 494 KRGNSGLVKTSSSLDRETTPVYTLVVRATDGGGKEVTSSLTVILDDVNDNAPVFSRPEGY 553

Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
           T  V ++  +G +V  V ATD D GINA   YSL S      VA +  +F+I+ +TG I 
Sbjct: 554 TFEV-QEGGVGLSVGTVQATDRDSGINAATLYSLKS------VADY-SKFIIDSKTGVIK 605

Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
           T+  LDRET     + V ARD G P LS    + ++V D+ND+ P F Q+ Y+  + E  
Sbjct: 606 TSFSLDRETQDQLNIRVIARDTGSPQLSAEVGIIVNVTDINDHRPAFSQRQYSVTVQEKR 665

Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654
                +  + ATD+D G+N  +HY +D       SF +D  +G + T   LDRE  A + 
Sbjct: 666 -ASHVILTLTATDSDRGINSALHYMID-SGNFGNSFTLDALTGSLSTTGPLDREVRAEYT 723

Query: 655 LKAVAID--GGTP---PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
           L     D  G      P   + +V++ IED+ND+ PVF     +  I E++  GT I ++
Sbjct: 724 LLVFVSDLQGNASLGIPLRDSAVVNVFIEDMNDNSPVFPQSQYSLTIPEDTAPGTGIIQV 783

Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
           +A D D G +  +HYSI  G+    F ++    S  A +     LD + PR +    +  
Sbjct: 784 QARDIDSGISQNLHYSIVSGNSLGRFFID----SSSARVYVKSPLDRDPPRNEGAYTL-- 837

Query: 770 ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVGPFGRVPA---YDADVTD 825
                     V I ++DVND+ P     Q +++    +   +G     P+    D     
Sbjct: 838 ---------EVTITISDVNDSPPEFS--QAMYSVRIPENITLGTVVLQPSCVDRDLGTNG 886

Query: 826 KLQYRILSGNNAN--LILLNETTGSMTLSPQLNTNV-PKLATMEVSVTD 871
           ++ Y I SGN+       +N ++G++++S + + +   K  ++ ++ TD
Sbjct: 887 QISYHISSGNSETPPRFSVNPSSGALSVSTEFDFDTGRKSYSLVLTATD 935



 Score =  263 bits (645), Expect = 4e-68
 Identities = 255/915 (27%), Positives = 410/915 (44%), Gaps = 103/915 (11%)

Query: 21  PVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXX 80
           P F   QY   + E   +GT VLT++A D +   N ++ Y         L+ ED      
Sbjct: 27  PRFVETQYVGRLPENQPTGTGVLTVRAVDNE---NDQITYQ--------LSGEDGR---- 71

Query: 81  XXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVL-VKATD-QASPVSDRLSSTATIHV 138
                    F+I+  +G + +  ++DREK+    +L  KA    A            + V
Sbjct: 72  ---------FKINSVTGEITSNVNIDREKLPGSNLLEFKAIAYDAKGAGYDYRVDVPVRV 122

Query: 139 NIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQM 198
            I D NDN P F    Y++SV E+   T       +KATDAD G N+ I+Y+I GGN   
Sbjct: 123 QIEDVNDNTPVFINTPYSISVKENTLGTTG---FAVKATDADQGQNALIKYSITGGNEAN 179

Query: 199 QFSIDSLSGDVSLVK---TLDYEQVRSYRLVIRAQD--GGSPSRSNTTQLLINIRDVNDN 253
            F I +  G +S+      LDYE+ +S+ L + A D  G + SR+  T + I + DV+D 
Sbjct: 180 MFKIGAYEGTISVFPDSGVLDYEKYKSFNLTVSASDLGGVNGSRTAVTSVFIRVEDVDDL 239

Query: 254 APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313
              F    +   V+E+   G+ +  V A D D  +N  ++Y + D+  T +   P   +P
Sbjct: 240 PAVFSPDYYTAKVAESSTKGFYVTTVTARDGDLSLNKPVSYFI-DQGITTS---PQHYEP 295

Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373
            S  +     + +   A  Q+ +T  +   P                     F+   Y  
Sbjct: 296 VSSSIKAISTIHKAVFATVQITITDINDNAPK--------------------FVNLPYSG 335

Query: 374 ELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431
            + E+ P G  V+ +TA DAD  DN +  Y +TG    G+F ++S+   G + V+  +D 
Sbjct: 336 TVPENSPTGLTVLRVTAQDADSGDNAKFTYSLTG--AAGKFVVSSE---GYVVVSGNIDR 390

Query: 432 KQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPY-----TASVFEDAPIGT 486
           + +  Y   VS +D+    +  +    I D++    +F   P      T + F+     +
Sbjct: 391 ETQDTYEFKVSVSDADLGPNADVRFSFIPDSSGLDKLFTIDPVSGDIKTLATFDREERVS 450

Query: 487 TVLVVSATDSDVGINAQITYSLSSEI----SNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
             L +   D   G   +  Y  +        N+     D        +G + T+  LDRE
Sbjct: 451 YGLGIRVIDQPSGQQGRYVYIANKRFIRSRDNQTTRKGDNIANKRGNSGLVKTSSSLDRE 510

Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF-KQQLYTANIMEDALVGTSVS 601
           T   Y L V A DGG   +  T+ + + + DVNDN PVF + + YT  + E   VG SV 
Sbjct: 511 TTPVYTLVVRATDGGGKEV--TSSLTVILDDVNDNAPVFSRPEGYTFEVQEGG-VGLSVG 567

Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
            V ATD D G+N    Y L     +   F+ID  +GVI+T+ +LDRE+    +++ +A D
Sbjct: 568 TVQATDRDSGINAATLYSL-KSVADYSKFIIDSKTGVIKTSFSLDRETQDQLNIRVIARD 626

Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
            G+P  S+ V + + + DIND  P F     +  + E       I  + A D D G N+ 
Sbjct: 627 TGSPQLSAEVGIIVNVTDINDHRPAFSQRQYSVTVQEKR-ASHVILTLTATDSDRGINSA 685

Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI--------RAASPP 773
           +HY I  G+  NSF+L+   GS    L T   LD E  R +Y L++         +   P
Sbjct: 686 LHYMIDSGNFGNSFTLDALTGS----LSTTGPLDRE-VRAEYTLLVFVSDLQGNASLGIP 740

Query: 774 LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRI 831
           L +   V + + D+NDN+PV    Q      +D  P     +V A D D  ++  L Y I
Sbjct: 741 LRDSAVVNVFIEDMNDNSPVFPQSQYSLTIPEDTAPGTGIIQVQARDIDSGISQNLHYSI 800

Query: 832 LSGNNANLILLNETTGSMTLSPQLNTNVPK---LATMEVSVT-DGVNEIK---AMMQLSV 884
           +SGN+     ++ ++  + +   L+ + P+     T+EV++T   VN+     +    SV
Sbjct: 801 VSGNSLGRFFIDSSSARVYVKSPLDRDPPRNEGAYTLEVTITISDVNDSPPEFSQAMYSV 860

Query: 885 RLITEEMLLNSITVR 899
           R I E + L ++ ++
Sbjct: 861 R-IPENITLGTVVLQ 874



 Score =  214 bits (522), Expect = 3e-53
 Identities = 161/480 (33%), Positives = 240/480 (50%), Gaps = 44/480 (9%)

Query: 94  GRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDD-NDNYPQFSE 152
           G SG + T +SLDRE    YT++V+ATD        ++S+ T+   I+DD NDN P FS 
Sbjct: 496 GNSGLVKTSSSLDRETTPVYTLVVRATDGGGK---EVTSSLTV---ILDDVNDNAPVFSR 549

Query: 153 -KTYTVSVDED-ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVS 210
            + YT  V E  + ++    +  ++ATD D G N+A  Y++       +F IDS +G + 
Sbjct: 550 PEGYTFEVQEGGVGLS----VGTVQATDRDSGINAATLYSLKSVADYSKFIIDSKTGVIK 605

Query: 211 LVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENV 270
              +LD E      + + A+D GSP  S    +++N+ D+ND+ P F    +  +V E  
Sbjct: 606 TSFSLDRETQDQLNIRVIARDTGSPQLSAEVGIIVNVTDINDHRPAFSQRQYSVTVQEK- 664

Query: 271 PIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA 330
              + I+ + A D+D G+N+ L Y M D   +GN     T+D  +G + T+G LDRE +A
Sbjct: 665 RASHVILTLTATDSDRGINSALHY-MID---SGNFGNSFTLDALTGSLSTTGPLDREVRA 720

Query: 331 KYQLLVTATD-GGDP----PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
           +Y LLV  +D  G+     P   +A               F   QY + + ED  PGT +
Sbjct: 721 EYTLLVFVSDLQGNASLGIPLRDSAVVNVFIEDMNDNSPVFPQSQYSLTIPEDTAPGTGI 780

Query: 386 VTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443
           + + A D D      LHY I  GN+ GRF I S + R  + V  PLD    R        
Sbjct: 781 IQVQARDIDSGISQNLHYSIVSGNSLGRFFIDSSSAR--VYVKSPLDRDPPR-------- 830

Query: 444 TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503
            + G  + T  V I I+D N+  P F  A Y+  + E+  +GT VL  S  D D+G N Q
Sbjct: 831 -NEG--AYTLEVTITISDVNDSPPEFSQAMYSVRIPENITLGTVVLQPSCVDRDLGTNGQ 887

Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET-MSGYLLTVTARDGGVPSLS 562
           I+Y +SS  S         +F +NP +GA++ +   D +T    Y L +TA D G P+LS
Sbjct: 888 ISYHISSGNSET-----PPRFSVNPSSGALSVSTEFDFDTGRKSYSLVLTATDKGEPALS 942



 Score =  151 bits (365), Expect = 4e-34
 Identities = 108/342 (31%), Positives = 173/342 (50%), Gaps = 44/342 (12%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           +NV D NDH P F  +QY  +V+E  +S   +LTL ATD D G N+ + Y I+       
Sbjct: 640 VNVTDINDHRPAFSQRQYSVTVQEKRASHV-ILTLTATDSDRGINSALHYMID------- 691

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS--D 128
                            + F +D  +G+L T   LDRE  A YT+LV  +D     S   
Sbjct: 692 ------------SGNFGNSFTLDALTGSLSTTGPLDREVRAEYTLLVFVSDLQGNASLGI 739

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            L  +A ++V I D NDN P F +  Y++++ ED        I +++A D D G +  + 
Sbjct: 740 PLRDSAVVNVFIEDMNDNSPVFPQSQYSLTIPED--TAPGTGIIQVQARDIDSGISQNLH 797

Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
           Y+I+ GN+  +F IDS S  V +   LD +  R+        +G     + T ++ I I 
Sbjct: 798 YSIVSGNSLGRFFIDSSSARVYVKSPLDRDPPRN--------EG-----AYTLEVTITIS 844

Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
           DVND+ P F  +++   + EN+ +G  +++    D D G N +++Y ++    +GN + P
Sbjct: 845 DVNDSPPEFSQAMYSVRIPENITLGTVVLQPSCVDRDLGTNGQISYHIS----SGNSETP 900

Query: 309 --ITIDPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDPPRS 347
              +++P SG +  S + D +T  K Y L++TATD G+P  S
Sbjct: 901 PRFSVNPSSGALSVSTEFDFDTGRKSYSLVLTATDKGEPALS 942



 Score =  123 bits (296), Expect = 8e-26
 Identities = 130/421 (30%), Positives = 184/421 (43%), Gaps = 53/421 (12%)

Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523
           N  P F    Y   + E+ P GT VL V A D++   N QITY LS E         D +
Sbjct: 24  NSPPRFVETQYVGRLPENQPTGTGVLTVRAVDNE---NDQITYQLSGE---------DGR 71

Query: 524 FVINPQTGAITTNKLLDRETMSGYLL------TVTARDGGVPSLSDTTDVEISVVDVNDN 577
           F IN  TG IT+N  +DRE + G  L         A+  G     D   V + + DVNDN
Sbjct: 72  FKINSVTGEITSNVNIDREKLPGSNLLEFKAIAYDAKGAGYDYRVDVP-VRVQIEDVNDN 130

Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637
            PVF    Y+ ++ E+ L GT+   V ATDAD G N  I Y +   + E   F I    G
Sbjct: 131 TPVFINTPYSISVKENTL-GTTGFAVKATDADQGQNALIKYSITGGN-EANMFKIGAYEG 188

Query: 638 VIRT---NKALDRESVATHDLKAVAIDGGTPPQSSTVI--VHIKIEDINDSPPVFESDCL 692
            I     +  LD E   + +L   A D G    S T +  V I++ED++D P VF  D  
Sbjct: 189 TISVFPDSGVLDYEKYKSFNLTVSASDLGGVNGSRTAVTSVFIRVEDVDDLPAVFSPDYY 248

Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752
           T  ++E+S  G  +  + A D D   N  V Y I  G  ++    E    S KA + T+ 
Sbjct: 249 TAKVAESSTKGFYVTTVTARDGDLSLNKPVSYFIDQGITTSPQHYEPVSSSIKA-ISTI- 306

Query: 753 DLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG- 811
                     ++ V             V+I +TD+NDNAP   +         +  P G 
Sbjct: 307 ----------HKAVF----------ATVQITITDINDNAPKFVNLP-YSGTVPENSPTGL 345

Query: 812 PFGRVPAYDADVTDKLQYRI-LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVT 870
              RV A DAD  D  ++   L+G     ++ +E  G + +S  ++         +VSV+
Sbjct: 346 TVLRVTAQDADSGDNAKFTYSLTGAAGKFVVSSE--GYVVVSGNIDRETQDTYEFKVSVS 403

Query: 871 D 871
           D
Sbjct: 404 D 404



 Score = 95.1 bits (226), Expect = 2e-17
 Identities = 69/210 (32%), Positives = 111/210 (52%), Gaps = 15/210 (7%)

Query: 567 VEISVVDVNDNEPV-FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625
           +E +++    N P  F +  Y   + E+   GT V  V A D +   N +I Y+L  +D 
Sbjct: 14  IEAALIQGQANSPPRFVETQYVGRLPENQPTGTGVLTVRAVDNE---NDQITYQLSGED- 69

Query: 626 EEGSFVIDPASGVIRTNKALDRESVATHDL---KAVAID--GGTPPQSSTVIVHIKIEDI 680
             G F I+  +G I +N  +DRE +   +L   KA+A D  G        V V ++IED+
Sbjct: 70  --GRFKINSVTGEITSNVNIDREKLPGSNLLEFKAIAYDAKGAGYDYRVDVPVRVQIEDV 127

Query: 681 NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR 740
           ND+ PVF +   +  + EN+ +GTT   ++A D D+G NA++ YSI GG+++N F +   
Sbjct: 128 NDNTPVFINTPYSISVKENT-LGTTGFAVKATDADQGQNALIKYSITGGNEANMFKIGAY 186

Query: 741 QGSDKAELVTMVDLDYESPRKKYELVIRAA 770
           +G+      + V LDYE   K + L + A+
Sbjct: 187 EGTISVFPDSGV-LDYEK-YKSFNLTVSAS 214



 Score = 84.2 bits (199), Expect = 5e-14
 Identities = 70/243 (28%), Positives = 115/243 (47%), Gaps = 42/243 (17%)

Query: 1   MSVPFCIHQQINVL--DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEV 58
           + +P      +NV   D ND+SPVF   QY  ++ E  + GT ++ ++A D D G +  +
Sbjct: 737 LGIPLRDSAVVNVFIEDMNDNSPVFPQSQYSLTIPEDTAPGTGIIQVQARDIDSGISQNL 796

Query: 59  EYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVK 118
            Y+I  V+ ++L                   F ID  S  +  ++ LDR+          
Sbjct: 797 HYSI--VSGNSLGR-----------------FFIDSSSARVYVKSPLDRD---------- 827

Query: 119 ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178
                 P  +  + T  + + I D ND+ P+FS+  Y+V + E+I++    V+ +    D
Sbjct: 828 ------PPRNEGAYTLEVTITISDVNDSPPEFSQAMYSVRIPENITL--GTVVLQPSCVD 879

Query: 179 ADVGANSAIRYAIIGGN--TQMQFSIDSLSGDVSLVKTLDYEQVR-SYRLVIRAQDGGSP 235
            D+G N  I Y I  GN  T  +FS++  SG +S+    D++  R SY LV+ A D G P
Sbjct: 880 RDLGTNGQISYHISSGNSETPPRFSVNPSSGALSVSTEFDFDTGRKSYSLVLTATDKGEP 939

Query: 236 SRS 238
           + S
Sbjct: 940 ALS 942


>UniRef50_UPI0000660C02 Cluster: Homolog of Brachydanio rerio
           "Protocadherin2-gamma-v12-A.; n=1; Takifugu
           rubripes|Rep: Homolog of Brachydanio rerio
           "Protocadherin2-gamma-v12-A. - Takifugu rubripes
          Length = 1441

 Score =  273 bits (670), Expect = 4e-71
 Identities = 253/944 (26%), Positives = 415/944 (43%), Gaps = 99/944 (10%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + + D ND++PVF+ ++    + E A  G+  +  KA D DIG N    YT        L
Sbjct: 93  VEITDINDNAPVFQKEEKRFEISESAIVGSKFMLEKAIDPDIGMNGLQRYT--------L 144

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            P D                  DG +   ++ +  LDREK    ++L+ A D   P   +
Sbjct: 145 KPSDNFVLKLHTES--------DGDKKVEMILQKPLDREKQEHISLLLTAEDGGEP---Q 193

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           ++ T  I+V ++D NDN P F++  Y  ++ E+       +I K+ A+DAD G++  + Y
Sbjct: 194 MTGTMRIYVAVLDVNDNAPVFTKPVYKANIAEN--AVRGTLITKVSASDADKGSHGEVSY 251

Query: 190 AIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            I          F ++S  GDV L   +DYE+ + Y + + A D G    S++++++I++
Sbjct: 252 VIANSMDPASNLFHVNS-EGDVILNGPIDYEREKHYDIDVEAIDSGG--LSDSSKIIIDV 308

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            DVNDN P         SV+E+  +   I  +   D D   N ++   +       N ++
Sbjct: 309 IDVNDNKPTINIISASGSVTEDSALKTVIALMSVNDPDSENNGKVQCMI-------NENI 361

Query: 308 PITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
           P  I   S  VY   T  +LDRE +++Y + V+ +D G P  S++ T             
Sbjct: 362 PFEIKFTSNNVYSLLTERELDRERESEYNITVSCSDEGVPSLSSSVTLTLQISDVNDNPP 421

Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRG---RFSITSQNG 419
            F    YE  + E+  PG  V T+ A D D  ++ R+ Y +   +  G      ++    
Sbjct: 422 VFERSSYEAYIVENNTPGLSVFTVKARDTDWNQNARVSYILEDSSVNGVPVSSYVSVSAD 481

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAP---------- 467
            G++   +  D++Q + +   V A D G    S    V+I I D N+  P          
Sbjct: 482 SGVVHAVRSFDYEQIKDFHFLVKAQDGGSPPLSSNVSVKILIQDQNDNPPQVLYPVQTGG 541

Query: 468 --VFENAPYTASV----FEDAPIGTTVLVVSATDSDVGINAQIT----------YSLSSE 511
             V E  P +A V     ED  +G   L       D     +I             L+  
Sbjct: 542 SMVAEMVPRSADVGYLSAEDPDVGINALKAYTISKDDCFTLKIKEIENGRKVPELVLNKS 601

Query: 512 ISNEAVAHHDQQFVI----NP-QTG-AITTNKLLDRETMSGYLLT-VTARDGGVPSLSDT 564
           +  E  A H          NP ++G A  T K+LD       + T + A+D G P +   
Sbjct: 602 LDREKKAIHSLFLTAVDGGNPVKSGTAKITVKVLDVNDQCSRIRTYIFAKDKGHPQMEGH 661

Query: 565 TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624
             V+I V+D+NDN P          I EDA  G+ V+ + A D D G NG++   L PKD
Sbjct: 662 CRVQIMVIDINDNAPEIILTSVPNPIREDAQRGSVVALIRARDEDSGNNGKVMLHL-PKD 720

Query: 625 REEGSFVIDPASG---VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681
                F + P+ G    + T+  LDRE+++ ++++  A D G+PP SS  I+ + I D+N
Sbjct: 721 ---SPFTLKPSFGNNYALVTSGVLDRETISEYNIEITATDSGSPPLSSKKIIPVSITDVN 777

Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN-SFSLETR 740
           D+PPVF       Y+ EN   G+ +  + A D D G NA + YSI      + S S    
Sbjct: 778 DNPPVFTQPSYNVYLKENGVPGSILYSVSASDLDFGENAKISYSILDSKVQDVSVSSYVY 837

Query: 741 QGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP--VMK 795
             SD   + +M   DYE   K +++ ++A    SP L ++  V + + D NDNAP  +  
Sbjct: 838 INSDNGSIYSMHSFDYEK-LKVFQIRVQAKDQGSPSLSSNTTVHVFILDQNDNAPAVIYP 896

Query: 796 DFQIIFNNYKDCFPVGP-----FGRVPAYDADVTDK--LQYRILSGNNANLILLNETTGS 848
               + +      P          +V A DAD      + YR+    +A+L  +N+ TG 
Sbjct: 897 SSAALGSLSHQRMPRSAKAGHLLTKVTAVDADSGHNAWISYRLAEATDASLFTVNQYTGE 956

Query: 849 MTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEML 892
           +     ++        + + + D    I++   ++V ++ E+ L
Sbjct: 957 VRTKRAVSEQDDSSQRLLIEIKDDGEPIQS-STVTVSVLLEDGL 999



 Score =  241 bits (589), Expect = 3e-61
 Identities = 227/792 (28%), Positives = 352/792 (44%), Gaps = 78/792 (9%)

Query: 97  GALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT 156
           GALL +  +DRE + R T       Q +   +       + V I D NDN P F ++   
Sbjct: 54  GALLVKEKIDREALCRQTTPCALHFQVT--LENPLELFPVTVEITDINDNAPVFQKEEKR 111

Query: 157 VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII-GGNTQMQFSIDSLSGD----VSL 211
             + E   V    ++ K  A D D+G N   RY +    N  ++   +S  GD    + L
Sbjct: 112 FEISESAIVGSKFMLEK--AIDPDIGMNGLQRYTLKPSDNFVLKLHTES-DGDKKVEMIL 168

Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271
            K LD E+     L++ A+DGG P  + T ++ + + DVNDNAP F   +++ +++EN  
Sbjct: 169 QKPLDREKQEHISLLLTAEDGGEPQMTGTMRIYVAVLDVNDNAPVFTKPVYKANIAENAV 228

Query: 272 IGYSIVRVQAYDADEGVNAELTYTMTDK-DYTGNVDLPITIDPRSGWVYTSGQLDRETQA 330
            G  I +V A DAD+G + E++Y + +  D   N+     ++   G V  +G +D E + 
Sbjct: 229 RGTLITKVSASDADKGSHGEVSYVIANSMDPASNL---FHVN-SEGDVILNGPIDYEREK 284

Query: 331 KYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTA 390
            Y + V A D G    S+                  +     V   ED    T +  ++ 
Sbjct: 285 HYDIDVEAIDSGGLSDSSKIIIDVIDVNDNKPTINIISASGSV--TEDSALKTVIALMSV 342

Query: 391 TDADEDNRLHYE-ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG-- 447
            D D +N    + +   N       TS N   L+T  + LD ++E  Y +TVS +D G  
Sbjct: 343 NDPDSENNGKVQCMINENIPFEIKFTSNNVYSLLT-ERELDRERESEYNITVSCSDEGVP 401

Query: 448 GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507
             S +  + + I+D N+  PVFE + Y A + E+   G +V  V A D+D   NA+++Y 
Sbjct: 402 SLSSSVTLTLQISDVNDNPPVFERSSYEAYIVENNTPGLSVFTVKARDTDWNQNARVSYI 461

Query: 508 L-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566
           L  S ++   V+ +     ++  +G +   +  D E +  +   V A+DGG P LS    
Sbjct: 462 LEDSSVNGVPVSSY---VSVSADSGVVHAVRSFDYEQIKDFHFLVKAQDGGSPPLSSNVS 518

Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALVGTS--VSQVGATDADVGLNGRIHYELDPKD 624
           V+I + D NDN P     + T   M   +V  S  V  + A D DVG+N    Y +   D
Sbjct: 519 VKILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYLSAEDPDVGINALKAYTISKDD 578

Query: 625 REEGSF-VIDPASGV--IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681
                   I+    V  +  NK+LDRE  A H L   A+DGG P +S T  + +K+ D+N
Sbjct: 579 CFTLKIKEIENGRKVPELVLNKSLDREKKAIHSLFLTAVDGGNPVKSGTAKITVKVLDVN 638

Query: 682 D--------------SPPVFESDC----LTFYISENSP----------------IGTTIG 707
           D                P  E  C    +   I++N+P                 G+ + 
Sbjct: 639 DQCSRIRTYIFAKDKGHPQMEGHCRVQIMVIDINDNAPEIILTSVPNPIREDAQRGSVVA 698

Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
            IRA D D G N  V   +      + F+L+   G++ A LVT   LD E+   +Y + I
Sbjct: 699 LIRARDEDSGNNGKVMLHL---PKDSPFTLKPSFGNNYA-LVTSGVLDRET-ISEYNIEI 753

Query: 768 RA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY--KDCFPVGPFGRVPAYDAD 822
            A    SPPL +   + + +TDVNDN PV    Q  +N Y  ++  P      V A D D
Sbjct: 754 TATDSGSPPLSSKKIIPVSITDVNDNPPVFT--QPSYNVYLKENGVPGSILYSVSASDLD 811

Query: 823 VTD--KLQYRIL 832
             +  K+ Y IL
Sbjct: 812 FGENAKISYSIL 823



 Score =  173 bits (422), Expect = 4e-41
 Identities = 172/620 (27%), Positives = 265/620 (42%), Gaps = 77/620 (12%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + + D ND+ PVFE   YEA + E  + G +V T+KA D D  +NA V Y +E  + + +
Sbjct: 411  LQISDVNDNPPVFERSSYEAYIVENNTPGLSVFTVKARDTDWNQNARVSYILEDSSVNGV 470

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           V     +   SG +    S D E++  +  LVKA D  SP    L
Sbjct: 471  P--------------VSSYVSVSADSGVVHAVRSFDYEQIKDFHFLVKAQDGGSPP---L 513

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            SS  ++ + I D NDN PQ      T        V  +  +  + A D DVG N+   Y 
Sbjct: 514  SSNVSVKILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYLSAEDPDVGINALKAYT 573

Query: 191  IIGGNTQMQFSIDSLSG-----DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
            I   +      I  +       ++ L K+LD E+   + L + A DGG+P +S T ++ +
Sbjct: 574  ISKDDC-FTLKIKEIENGRKVPELVLNKSLDREKKAIHSLFLTAVDGGNPVKSGTAKITV 632

Query: 246  NIRDVNDNAPRFYTSLFQES------------------VSENVP--IGYSIVRVQAYDAD 285
             + DVND   R  T +F +                   +++N P  I  S+      DA 
Sbjct: 633  KVLDVNDQCSRIRTYIFAKDKGHPQMEGHCRVQIMVIDINDNAPEIILTSVPNPIREDAQ 692

Query: 286  EG-VNAELTYTMTDKDYTGNV------DLPITIDPRSGWVY---TSGQLDRETQAKYQLL 335
             G V A +     D    G V      D P T+ P  G  Y   TSG LDRET ++Y + 
Sbjct: 693  RGSVVALIRARDEDSGNNGKVMLHLPKDSPFTLKPSFGNNYALVTSGVLDRETISEYNIE 752

Query: 336  VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD- 394
            +TATD G PP S+                 F    Y V L E+  PG+ + +++A+D D 
Sbjct: 753  ITATDSGSPPLSSKKIIPVSITDVNDNPPVFTQPSYNVYLKENGVPGSILYSVSASDLDF 812

Query: 395  -EDNRLHYEITGGNTRGRFSITS----QNGRGLITVAQPLDFKQERRYVLTVSATDSG-- 447
             E+ ++ Y I     +   S++S     +  G I      D+++ + + + V A D G  
Sbjct: 813  GENAKISYSILDSKVQD-VSVSSYVYINSDNGSIYSMHSFDYEKLKVFQIRVQAKDQGSP 871

Query: 448  GRSDTAMVQINITDANNYAP--VFENAPYTASVF-----EDAPIGTTVLVVSATDSDVGI 500
              S    V + I D N+ AP  ++ ++    S+        A  G  +  V+A D+D G 
Sbjct: 872  SLSSNTTVHVFILDQNDNAPAVIYPSSAALGSLSHQRMPRSAKAGHLLTKVTAVDADSGH 931

Query: 501  NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560
            NA I+Y L       A A     F +N  TG + T + +  +  S   L +  +D G P 
Sbjct: 932  NAWISYRL-------AEATDASLFTVNQYTGEVRTKRAVSEQDDSSQRLLIEIKDDGEPI 984

Query: 561  LSDTTDVEISVVDVNDNEPV 580
             S T  V + + D   +EP+
Sbjct: 985  QSSTVTVSVLLED-GLHEPI 1003



 Score =  147 bits (355), Expect = 6e-33
 Identities = 106/354 (29%), Positives = 176/354 (49%), Gaps = 40/354 (11%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           QI V+D ND++P   +      +RE A  G+ V  ++A D+D G N +V   +   +  T
Sbjct: 665 QIMVIDINDNAPEIILTSVPNPIREDAQRGSVVALIRARDEDSGNNGKVMLHLPKDSPFT 724

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
           L P                     G + AL+T   LDRE ++ Y + + ATD  SP    
Sbjct: 725 LKPS-------------------FGNNYALVTSGVLDRETISEYNIEITATDSGSP---P 762

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           LSS   I V+I D NDN P F++ +Y V + E  +     ++  + A+D D G N+ I Y
Sbjct: 763 LSSKKIIPVSITDVNDNPPVFTQPSYNVYLKE--NGVPGSILYSVSASDLDFGENAKISY 820

Query: 190 AIIGGNTQ-----MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
           +I+    Q         I+S +G +  + + DYE+++ +++ ++A+D GSPS S+ T + 
Sbjct: 821 SILDSKVQDVSVSSYVYINSDNGSIYSMHSFDYEKLKVFQIRVQAKDQGSPSLSSNTTVH 880

Query: 245 INIRDVNDNAPR-FYT------SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297
           + I D NDNAP   Y       SL  + +  +   G+ + +V A DAD G NA ++Y + 
Sbjct: 881 VFILDQNDNAPAVIYPSSAALGSLSHQRMPRSAKAGHLLTKVTAVDADSGHNAWISYRLA 940

Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
           +     +  L  T++  +G V T   +  +  +  +LL+   D G+P +S+T T
Sbjct: 941 E---ATDASL-FTVNQYTGEVRTKRAVSEQDDSSQRLLIEIKDDGEPIQSSTVT 990



 Score =  113 bits (273), Expect = 5e-23
 Identities = 77/248 (31%), Positives = 120/248 (48%), Gaps = 11/248 (4%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            F +D   G L+    +DRE +   +     T Q   V++       I V I D NDNYP 
Sbjct: 1200 FSVDAGKGELVVNDRIDREALCGQSASCVLTLQV--VTENPLQLHRIEVEIKDINDNYPN 1257

Query: 150  FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD- 208
            F      + + E  +     ++    A D DVG+NS   Y +   +      +  LSGD 
Sbjct: 1258 FLTGERFLKIAESTAAGVRFLLET--AQDPDVGSNSVKSYTL-SKDECFSLKMKDLSGDR 1314

Query: 209  ----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
                + L KTLD E+  S+ L++ A DGG+P ++ TT +++ + D NDN P F   L+  
Sbjct: 1315 QIPELVLDKTLDREKQDSHHLLLTAIDGGNPVKTGTTTIIVTVLDNNDNVPVFQKPLYNI 1374

Query: 265  SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
            S+ EN      +++V+A DADEGVN E+ Y+  +      + +   +D  +G ++  GQL
Sbjct: 1375 SLPENSSTSSVLLKVEATDADEGVNGEIEYSFPEHTPQDILSV-FRLDSSTGEIFLVGQL 1433

Query: 325  DRETQAKY 332
            D E    Y
Sbjct: 1434 DYEKSIMY 1441



 Score = 99.1 bits (236), Expect = 2e-18
 Identities = 62/196 (31%), Positives = 100/196 (51%), Gaps = 5/196 (2%)

Query: 455  VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
            +++ I D N+  P F        + E    G   L+ +A D DVG N+  +Y+LS +   
Sbjct: 1244 IEVEIKDINDNYPNFLTGERFLKIAESTAAGVRFLLETAQDPDVGSNSVKSYTLSKD--- 1300

Query: 515  EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
            E  +   +    + Q   +  +K LDRE    + L +TA DGG P  + TT + ++V+D 
Sbjct: 1301 ECFSLKMKDLSGDRQIPELVLDKTLDREKQDSHHLLLTAIDGGNPVKTGTTTIIVTVLDN 1360

Query: 575  NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE--GSFVI 632
            NDN PVF++ LY  ++ E++   + + +V ATDAD G+NG I Y       ++    F +
Sbjct: 1361 NDNVPVFQKPLYNISLPENSSTSSVLLKVEATDADEGVNGEIEYSFPEHTPQDILSVFRL 1420

Query: 633  DPASGVIRTNKALDRE 648
            D ++G I     LD E
Sbjct: 1421 DSSTGEIFLVGQLDYE 1436



 Score = 96.7 bits (230), Expect = 8e-18
 Identities = 78/274 (28%), Positives = 115/274 (41%), Gaps = 12/274 (4%)

Query: 490  VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
            VV     D+G+     +     ++ EA     Q F ++   G +  N  +DRE + G   
Sbjct: 1169 VVGNLAKDLGLGLSDIFDRKLRVAAEA---GKQYFSVDAGKGELVVNDRIDREALCGQSA 1225

Query: 550  T-VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
            + V        +      +E+ + D+NDN P F        I E    G       A D 
Sbjct: 1226 SCVLTLQVVTENPLQLHRIEVEIKDINDNYPNFLTGERFLKIAESTAAGVRFLLETAQDP 1285

Query: 609  DVGLNGRIHYELDPKDREEGSFVIDPASG-----VIRTNKALDRESVATHDLKAVAIDGG 663
            DVG N    Y L  KD E  S  +   SG      +  +K LDRE   +H L   AIDGG
Sbjct: 1286 DVGSNSVKSYTLS-KD-ECFSLKMKDLSGDRQIPELVLDKTLDREKQDSHHLLLTAIDGG 1343

Query: 664  TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
             P ++ T  + + + D ND+ PVF+       + ENS   + + ++ A D DEG N  + 
Sbjct: 1344 NPVKTGTTTIIVTVLDNNDNVPVFQKPLYNISLPENSSTSSVLLKVEATDADEGVNGEIE 1403

Query: 724  YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757
            YS       +  S+  R  S   E+  +  LDYE
Sbjct: 1404 YSFPEHTPQDILSV-FRLDSSTGEIFLVGQLDYE 1436



 Score = 75.8 bits (178), Expect = 2e-11
 Identities = 59/243 (24%), Positives = 108/243 (44%), Gaps = 6/243 (2%)

Query: 200  FSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF 257
            FS+D+  G++ +   +D E +  +S   V+  Q   + +     ++ + I+D+NDN P F
Sbjct: 1200 FSVDAGKGELVVNDRIDREALCGQSASCVLTLQVV-TENPLQLHRIEVEIKDINDNYPNF 1258

Query: 258  YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317
             T      ++E+   G   +   A D D G N+  +YT++  +        ++ D +   
Sbjct: 1259 LTGERFLKIAESTAAGVRFLLETAQDPDVGSNSVKSYTLSKDECFSLKMKDLSGDRQIPE 1318

Query: 318  VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377
            +     LDRE Q  + LL+TA DGG+P ++ T T              F    Y + L E
Sbjct: 1319 LVLDKTLDREKQDSHHLLLTAIDGGNPVKTGTTTIIVTVLDNNDNVPVFQKPLYNISLPE 1378

Query: 378  DEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSI-TSQNGRGLITVAQPLDFKQE 434
            +    + ++ + ATDADE  +  + Y       +   S+    +  G I +   LD+++ 
Sbjct: 1379 NSSTSSVLLKVEATDADEGVNGEIEYSFPEHTPQDILSVFRLDSSTGEIFLVGQLDYEKS 1438

Query: 435  RRY 437
              Y
Sbjct: 1439 IMY 1441



 Score = 56.4 bits (130), Expect = 1e-05
 Identities = 46/184 (25%), Positives = 85/184 (46%), Gaps = 12/184 (6%)

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG---- 421
            F+ G+  +++AE    G   +  TA D D  +      T       FS+  ++  G    
Sbjct: 1258 FLTGERFLKIAESTAAGVRFLLETAQDPDVGSNSVKSYTLSKDEC-FSLKMKDLSGDRQI 1316

Query: 422  -LITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASV 478
              + + + LD +++  + L ++A D G   ++ T  + + + D N+  PVF+   Y  S+
Sbjct: 1317 PELVLDKTLDREKQDSHHLLLTAIDGGNPVKTGTTTIIVTVLDNNDNVPVFQKPLYNISL 1376

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
             E++   + +L V ATD+D G+N +I YS       + ++     F ++  TG I     
Sbjct: 1377 PENSSTSSVLLKVEATDADEGVNGEIEYSFPEHTPQDILS----VFRLDSSTGEIFLVGQ 1432

Query: 539  LDRE 542
            LD E
Sbjct: 1433 LDYE 1436



 Score = 54.8 bits (126), Expect = 3e-05
 Identities = 35/103 (33%), Positives = 52/103 (50%), Gaps = 16/103 (15%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + VLD ND+ PVF+   Y  S+ E +S+ + +L ++ATD D G N E+EY+    T    
Sbjct: 1355 VTVLDNNDNVPVFQKPLYNISLPENSSTSSVLLKVEATDADEGVNGEIEYSFPEHT---- 1410

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARY 113
             P+D           +  VFR+D  +G +     LD EK   Y
Sbjct: 1411 -PQD-----------ILSVFRLDSSTGEIFLVGQLDYEKSIMY 1441


>UniRef50_UPI0000E4A946 Cluster: PREDICTED: similar to cadherin 23;
            n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
            similar to cadherin 23 - Strongylocentrotus purpuratus
          Length = 1482

 Score =  272 bits (668), Expect = 7e-71
 Identities = 266/904 (29%), Positives = 414/904 (45%), Gaps = 108/904 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + + + ND++PVF   QY+ S+ E +   T V  L+ATD D+G     E T EL+  +  
Sbjct: 325  VYLTNINDNTPVFSQSQYDVSLPENSVENTPVQQLEATDADVG----AELTFELLGYNN- 379

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSG--ALLTRASLDREKVARYTVLVKATDQASPVSD 128
                             D F I+  +G  ++   A  + E ++ Y +    +D      +
Sbjct: 380  -----------------DWFNINSSTGYISVSDTADFNAELLSVYFLTCVVSD-----GE 417

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE-DISVTDNPV----IAKIKATDADVGA 183
            R+S TA ++V + D NDN P F    Y+VS+ E ++ + +       I ++ ATDAD+  
Sbjct: 418  RVS-TALLNVTVTDVNDNPPLFQLDLYSVSIPEYNVDMLEEEDEGLNILQVLATDADINV 476

Query: 184  -NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYE-QVRSYRLVIRAQDGGSPSRSNTT 241
             N  + Y+I  GN + +F I+S +G +    ++D E +  ++ +V+ A DGG+PS + TT
Sbjct: 477  INRMLTYSIESGNEEGKFDINSTTGMIFRKASIDRETEEATFEMVVMAIDGGTPSMNGTT 536

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
             + I+I DVNDN P F  +L+   V EN   G  +  + A D D   + ++ YT+ +   
Sbjct: 537  LVTISIEDVNDNNPIFLAALYNAEVPENAAFGTLVANITAVDMDVD-SLDVLYTIEEAS- 594

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
                  P  ++ + G +  SG +D E Q  Y L VTATD  D  R  + T          
Sbjct: 595  ------PFLVN-QEGLITLSGTVDYEIQMTYNLTVTATDREDTSRQGSCTVMINIMDVND 647

Query: 362  XXXXF-MPGQYEVELAE-----DEPPGTP----VVTLTATDADEDNRLHYEITG------ 405
                F  P    + + E     D  PG+     ++TL ATD D +  L Y I        
Sbjct: 648  EPPEFDTPSPSSLSVNESAAYCDSLPGSDDCHVLITLQATDPDTNTDLRYSILDVKGYDE 707

Query: 406  ------GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD------SGGRSDTA 453
                  GN   +F + S+ G   + V   LD +  +R+ +TV   D      +  ++D+A
Sbjct: 708  NSRLVVGNFSDQFGVDSETGD--VFVRTELDRETVQRFDVTVVVDDMKAEENNDTQTDSA 765

Query: 454  MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV-VSATDSDVGINAQITYSLSSEI 512
             + I + D N+ AP F + P   +  E   +G  + V + A D D   N  + Y L  + 
Sbjct: 766  ELVITVLDVNDNAPEFIDLPDNFTTPETDQVGMVISVNILADDEDAEDNGIVIYELLDDA 825

Query: 513  SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572
                VA       I+  TG +T  + +D+E      +T  A+DGG P L+ T   +I + 
Sbjct: 826  GG-LVA-------ISETTGILTVKQPIDKELNDSLTITFCAKDGGDPPLNTTVTRQIFIT 877

Query: 573  DVNDNEPVFKQQL-YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631
            DVNDN PVF   L   A+I+ED   GT V  V ATDAD    G + Y +      E  FV
Sbjct: 878  DVNDNTPVFNVSLPNEASILEDTTNGTLVLTVYATDADPDF-GDLTYTISAGVGLE-DFV 935

Query: 632  IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF-ESD 690
            I+P +G I     LDRE  A + L  VA DG    +   + V I I D+ND+ P F ES 
Sbjct: 936  INPENGDITVQNELDREEQALYTLTVVASDG---IRQDNLEVTITILDVNDNHPEFTESF 992

Query: 691  CLTFYISENSPIGTTIGEIRAHDPDE--GPNAVVHYSIKGGDDSNSFSLETRQGSDKAEL 748
              +  ISE +  G+++  I A D DE    N+ V Y +   + S  F ++   G     +
Sbjct: 993  PESTTISETAEPGSSVAAIVAVDDDEPGTNNSAVRYIMTDENQSGFFKMDYVTG---VVI 1049

Query: 749  VTMVDLDYESPRKKYELVIRAA---SPPLWNDVR-VEILVTDVNDNAPVMKDFQIIFNNY 804
            +     D   P   Y LV+ A+    PPL  D R   ++VTD ND APV    +     Y
Sbjct: 1050 LNTTSTDALIP-GVYVLVVVASDLGDPPLMTDPRNFSVIVTDYNDEAPVFVQPKQGATVY 1108

Query: 805  KDCFPVGPFGRVPAYDADVTDK--LQYRILSGNNA----NLILLNETTGSMTLSPQLNTN 858
             D    G      A D D+ D   + +   +G  A        ++ETTG++ ++ + +  
Sbjct: 1109 VDENYSGHITTAEATDGDLGDNGVVTFAFDTGLGATDDYKYFTIDETTGAIEITSETDRE 1168

Query: 859  VPKL 862
              ++
Sbjct: 1169 TKEI 1172



 Score =  254 bits (622), Expect = 3e-65
 Identities = 247/819 (30%), Positives = 386/819 (47%), Gaps = 82/819 (10%)

Query: 11  INVLDCNDHSPVFEMQQY-EASVREGASSGTTV-LTLKATDQDIGKNAEVEYTIELVTAD 68
           I + D +D+ P F  +    A++ E +  GT +  +L+A D D G+   +  ++E     
Sbjct: 213 IRLSDVDDNPPTFTPKGVVNATIPEHSPRGTQLDFSLEAFDLDSGEAGRIILSLEDDEGI 272

Query: 69  TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
                +           V DV R+D  S       +LD E+++  T  +KA+D      +
Sbjct: 273 FYLVSETIFNSG-----VVDV-RVDNSS-------ALDFERISEVTFQIKASDAQG--GN 317

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
               TAT+++  I  NDN P FS+  Y VS+ E+ SV + PV  +++ATDADVGA   + 
Sbjct: 318 FSVVTATVYLTNI--NDNTPVFSQSQYDVSLPEN-SVENTPV-QQLEATDADVGAE--LT 371

Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDY--EQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           + ++G N    F+I+S +G +S+  T D+  E +  Y L     DG    R +T  L + 
Sbjct: 372 FELLGYNNDW-FNINSSTGYISVSDTADFNAELLSVYFLTCVVSDG---ERVSTALLNVT 427

Query: 247 IRDVNDNAPRFYTSLFQESVSE-NVPI------GYSIVRVQAYDADEGV-NAELTYTMTD 298
           + DVNDN P F   L+  S+ E NV +      G +I++V A DAD  V N  LTY++  
Sbjct: 428 VTDVNDNPPLFQLDLYSVSIPEYNVDMLEEEDEGLNILQVLATDADINVINRMLTYSIE- 486

Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRET-QAKYQLLVTATDGGDPPRSATATXXXXXX 357
              +GN +    I+  +G ++    +DRET +A ++++V A DGG P  + T        
Sbjct: 487 ---SGNEEGKFDINSTTGMIFRKASIDRETEEATFEMVVMAIDGGTPSMNGTTLVTISIE 543

Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN-RLHYEITGGNTRGRFSITS 416
                   F+   Y  E+ E+   GT V  +TA D D D+  + Y I   +    F +  
Sbjct: 544 DVNDNNPIFLAALYNAEVPENAAFGTLVANITAVDMDVDSLDVLYTIEEASP---FLV-- 598

Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATD--SGGRSDTAMVQINITDANNYAPVFEN-AP 473
            N  GLIT++  +D++ +  Y LTV+ATD     R  +  V INI D N+  P F+  +P
Sbjct: 599 -NQEGLITLSGTVDYEIQMTYNLTVTATDREDTSRQGSCTVMINIMDVNDEPPEFDTPSP 657

Query: 474 YTASVFEDAPI-----GT----TVLVVSATDSDVGINAQITYSL-----SSEISNEAVAH 519
            + SV E A       G+     ++ + ATD D   N  + YS+       E S   V +
Sbjct: 658 SSLSVNESAAYCDSLPGSDDCHVLITLQATDPDT--NTDLRYSILDVKGYDENSRLVVGN 715

Query: 520 HDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT----TDVEISVVDVN 575
              QF ++ +TG +     LDRET+  + +TV   D      +DT     ++ I+V+DVN
Sbjct: 716 FSDQFGVDSETGDVFVRTELDRETVQRFDVTVVVDDMKAEENNDTQTDSAELVITVLDVN 775

Query: 576 DNEPVFKQQLYTANIMEDALVGTSVS-QVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634
           DN P F          E   VG  +S  + A D D   NG + YEL   D   G   I  
Sbjct: 776 DNAPEFIDLPDNFTTPETDQVGMVISVNILADDEDAEDNGIVIYEL--LDDAGGLVAISE 833

Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT- 693
            +G++   + +D+E   +  +   A DGG PP ++TV   I I D+ND+ PVF       
Sbjct: 834 TTGILTVKQPIDKELNDSLTITFCAKDGGDPPLNTTVTRQIFITDVNDNTPVFNVSLPNE 893

Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753
             I E++  GT +  + A D D     +  Y+I  G     F +    G    ++    +
Sbjct: 894 ASILEDTTNGTLVLTVYATDADPDFGDLT-YTISAGVGLEDFVINPENG----DITVQNE 948

Query: 754 LDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP 792
           LD E  +  Y L + A+     +++ V I + DVNDN P
Sbjct: 949 LDREE-QALYTLTVVASDGIRQDNLEVTITILDVNDNHP 986



 Score =  233 bits (570), Expect = 5e-59
 Identities = 239/848 (28%), Positives = 372/848 (43%), Gaps = 115/848 (13%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I++ D ND++P+F    Y A V E A+ GT V  + A D D+  + +V YTIE  +   +
Sbjct: 540  ISIEDVNDNNPIFLAALYNAEVPENAAFGTLVANITAVDMDV-DSLDVLYTIEEASPFLV 598

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N E                       G +    ++D E    Y + V ATD+    + R 
Sbjct: 599  NQE-----------------------GLITLSGTVDYEIQMTYNLTVTATDRED--TSRQ 633

Query: 131  SSTATIHVNIIDDNDNYPQF-SEKTYTVSVDEDISVTDN-------PVIAKIKATDADVG 182
             S  T+ +NI+D ND  P+F +    ++SV+E  +  D+        V+  ++ATD D  
Sbjct: 634  GS-CTVMINIMDVNDEPPEFDTPSPSSLSVNESAAYCDSLPGSDDCHVLITLQATDPD-- 690

Query: 183  ANSAIRYAIIG------------GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ 230
             N+ +RY+I+             GN   QF +DS +GDV +   LD E V+ + + +   
Sbjct: 691  TNTDLRYSILDVKGYDENSRLVVGNFSDQFGVDSETGDVFVRTELDRETVQRFDVTVVVD 750

Query: 231  D----GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSI-VRVQAYDAD 285
            D      + +++++ +L+I + DVNDNAP F       +  E   +G  I V + A D D
Sbjct: 751  DMKAEENNDTQTDSAELVITVLDVNDNAPEFIDLPDNFTTPETDQVGMVISVNILADDED 810

Query: 286  EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP 345
               N  + Y + D    G +   + I   +G +     +D+E      +   A DGGDPP
Sbjct: 811  AEDNGIVIYELLDD--AGGL---VAISETTGILTVKQPIDKELNDSLTITFCAKDGGDPP 865

Query: 346  RSATATXXXXXXXXXXXXXXF-MPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEI 403
             + T T              F +    E  + ED   GT V+T+ ATDAD D   L Y I
Sbjct: 866  LNTTVTRQIFITDVNDNTPVFNVSLPNEASILEDTTNGTLVLTVYATDADPDFGDLTYTI 925

Query: 404  TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDAN 463
            + G     F I  +NG   ITV   LD +++  Y LTV A+D G R D   V I I D N
Sbjct: 926  SAGVGLEDFVINPENGD--ITVQNELDREEQALYTLTVVASD-GIRQDNLEVTITILDVN 982

Query: 464  NYAPVF-ENAPYTASVFEDAPIGTTVLVVSATDSD-VGI-NAQITYSLSSEISNEAVAHH 520
            +  P F E+ P + ++ E A  G++V  + A D D  G  N+ + Y ++ E       + 
Sbjct: 983  DNHPEFTESFPESTTISETAEPGSSVAAIVAVDDDEPGTNNSAVRYIMTDE-------NQ 1035

Query: 521  DQQFVINPQTGAITTNKLLDRETMSG-YLLTVTARD-GGVPSLSDTTDVEISVVDVNDNE 578
               F ++  TG +  N       + G Y+L V A D G  P ++D  +  + V D ND  
Sbjct: 1036 SGFFKMDYVTGVVILNTTSTDALIPGVYVLVVVASDLGDPPLMTDPRNFSVIVTDYNDEA 1095

Query: 579  PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP---KDREEGSFVIDPA 635
            PVF Q    A +  D      ++   ATD D+G NG + +  D       +   F ID  
Sbjct: 1096 PVFVQPKQGATVYVDENYSGHITTAEATDGDLGDNGVVTFAFDTGLGATDDYKYFTIDET 1155

Query: 636  SGVIRTNKALDRESVATHDLKAVAIDG----GTPPQSSTVIVHIKIEDINDSPPVF---- 687
            +G I      DRE+   +    + I G      P +SS V  ++++ D +D+ P +    
Sbjct: 1156 TGAIEITSETDRETKEIYIRLLLGIIGMNAKSDPIRSSQVTFYVQVNDTDDNEPAYWGER 1215

Query: 688  --------ESDCLTFYISENSPIGTTIGEI-RAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738
                      +    Y+ EN   GT +G +  A D D      ++Y I      + F L+
Sbjct: 1216 TGPEGPQDPPEAALLYVQENLGEGTFVGTVPEAVDLDSDLYNQIYYFIVSATSEDYFILD 1275

Query: 739  TRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW--------------NDVRVEILV 784
               G+     +T+V+      R ++ LVI A S P +              N  RV + V
Sbjct: 1276 KYSGN-----LTLVNPIDREKRPEFSLVIWADSNPDYEPDMNVIYDPLKEDNLARVTVTV 1330

Query: 785  TDVNDNAP 792
            +DVND+ P
Sbjct: 1331 SDVNDSPP 1338



 Score =  213 bits (520), Expect = 6e-53
 Identities = 215/764 (28%), Positives = 321/764 (42%), Gaps = 72/764 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEA-SVREGAS-----SGT----TVLTLKATDQDIGKNAEVEY 60
            IN++D ND  P F+     + SV E A+      G+     ++TL+ATD D   N ++ Y
Sbjct: 640  INIMDVNDEPPEFDTPSPSSLSVNESAAYCDSLPGSDDCHVLITLQATDPDT--NTDLRY 697

Query: 61   TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT 120
            +I       L+ +              D F +D  +G +  R  LDRE V R+ V V   
Sbjct: 698  SI-------LDVKGYDENSRLVVGNFSDQFGVDSETGDVFVRTELDRETVQRFDVTVVVD 750

Query: 121  D-QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA 179
            D +A   +D  + +A + + ++D NDN P+F +     +  E   V    +   I A D 
Sbjct: 751  DMKAEENNDTQTDSAELVITVLDVNDNAPEFIDLPDNFTTPETDQV-GMVISVNILADDE 809

Query: 180  DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239
            D   N  + Y ++     +  +I   +G +++ + +D E   S  +   A+DGG P  + 
Sbjct: 810  DAEDNGIVIYELLDDAGGL-VAISETTGILTVKQPIDKELNDSLTITFCAKDGGDPPLNT 868

Query: 240  TTQLLINIRDVNDNAPRFYTSLFQE-SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
            T    I I DVNDN P F  SL  E S+ E+   G  ++ V A DAD     +LTYT++ 
Sbjct: 869  TVTRQIFITDVNDNTPVFNVSLPNEASILEDTTNGTLVLTVYATDADPDFG-DLTYTISA 927

Query: 299  KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG-GDPPRSATATXXXXXX 357
                G  D    I+P +G +    +LDRE QA Y L V A+DG        T T      
Sbjct: 928  G--VGLEDF--VINPENGDITVQNELDREEQALYTLTVVASDGIRQDNLEVTITILDVND 983

Query: 358  XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE----DNRLHYEITGGNTRGRFS 413
                    F       E AE   PG+ V  + A D DE    ++ + Y +T  N  G F 
Sbjct: 984  NHPEFTESFPESTTISETAE---PGSSVAAIVAVDDDEPGTNNSAVRYIMTDENQSGFFK 1040

Query: 414  ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFE 470
            +    G  ++      D      YVL V A+D G     +D     + +TD N+ APVF 
Sbjct: 1041 MDYVTGVVILNTTST-DALIPGVYVLVVVASDLGDPPLMTDPRNFSVIVTDYNDEAPVFV 1099

Query: 471  NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
                 A+V+ D      +    ATD D+G N  +T++  + +         + F I+  T
Sbjct: 1100 QPKQGATVYVDENYSGHITTAEATDGDLGDNGVVTFAFDTGLG---ATDDYKYFTIDETT 1156

Query: 531  GAITTNKLLDRETMSGYLLTVTARDG----GVPSLSDTTDVEISVVDVNDNEPVF----- 581
            GAI      DRET   Y+  +    G      P  S      + V D +DNEP +     
Sbjct: 1157 GAIEITSETDRETKEIYIRLLLGIIGMNAKSDPIRSSQVTFYVQVNDTDDNEPAYWGERT 1216

Query: 582  -------KQQLYTANIMEDALVGTSVSQVG-ATDADVGLNGRIHYELDPKDREEGSFVID 633
                     +     + E+   GT V  V  A D D  L  +I+Y +     E+  F++D
Sbjct: 1217 GPEGPQDPPEAALLYVQENLGEGTFVGTVPEAVDLDSDLYNQIYYFIVSATSED-YFILD 1275

Query: 634  PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI-----------VHIKIEDIND 682
              SG +     +DRE      L   A           VI           V + + D+ND
Sbjct: 1276 KYSGNLTLVNPIDREKRPEFSLVIWADSNPDYEPDMNVIYDPLKEDNLARVTVTVSDVND 1335

Query: 683  SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
            SPP FE D  T  +  ++  G  +  + A DPD G NAV  Y+I
Sbjct: 1336 SPPRFEEDRYTAGVLYSTSFGVEVITVNAVDPDLGENAVTVYTI 1379



 Score =  204 bits (499), Expect = 2e-50
 Identities = 217/769 (28%), Positives = 350/769 (45%), Gaps = 79/769 (10%)

Query: 155 YTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS-GDVSL-V 212
           +T  ++++ S++ N    +  A    +   +  R+    G +Q    +D LS G+V L V
Sbjct: 121 FTSEIEDNGSISPNFGCGRYAAMTLTILPVNNGRFHSADGPSQRP--VDWLSTGEVVLTV 178

Query: 213 KTLDYEQVRSYRLVIRAQDGGSPSRS-NT-TQLLINIRDVNDNAPRFYTS-LFQESVSEN 269
              D +   + R  I   D   P    NT T + I + DV+DN P F    +   ++ E+
Sbjct: 179 VANDGDLGVNLRNAIEEDDDDQPMEQINTNTSIYIRLSDVDDNPPTFTPKGVVNATIPEH 238

Query: 270 VPIGYSI-VRVQAYDADEGVNAELTYTMTDKD-----YTGNVDLPITIDPRSGWVYTSGQ 323
            P G  +   ++A+D D G    +  ++ D +      +  +     +D R   V  S  
Sbjct: 239 SPRGTQLDFSLEAFDLDSGEAGRIILSLEDDEGIFYLVSETIFNSGVVDVR---VDNSSA 295

Query: 324 LDRE--TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381
           LD E  ++  +Q+  +   GG+    +  T              F   QY+V L E+   
Sbjct: 296 LDFERISEVTFQIKASDAQGGN---FSVVTATVYLTNINDNTPVFSQSQYDVSLPENSVE 352

Query: 382 GTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR--YVL 439
            TPV  L ATDAD    L +E+ G N    F+I S  G   I+V+   DF  E    Y L
Sbjct: 353 NTPVQQLEATDADVGAELTFELLGYNNDW-FNINSSTG--YISVSDTADFNAELLSVYFL 409

Query: 440 TVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASV-------FEDAPIGTTVLVVS 492
           T   +D G R  TA++ + +TD N+  P+F+   Y+ S+        E+   G  +L V 
Sbjct: 410 TCVVSD-GERVSTALLNVTVTDVNDNPPLFQLDLYSVSIPEYNVDMLEEEDEGLNILQVL 468

Query: 493 ATDSDVG-INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG-YLLT 550
           ATD+D+  IN  +TYS+ S   NE     + +F IN  TG I     +DRET    + + 
Sbjct: 469 ATDADINVINRMLTYSIES--GNE-----EGKFDINSTTGMIFRKASIDRETEEATFEMV 521

Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610
           V A DGG PS++ TT V IS+ DVNDN P+F   LY A + E+A  GT V+ + A D DV
Sbjct: 522 VMAIDGGTPSMNGTTLVTISIEDVNDNNPIFLAALYNAEVPENAAFGTLVANITAVDMDV 581

Query: 611 GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST 670
             +  + Y ++    E   F+++   G+I  +  +D E   T++L   A D     +  +
Sbjct: 582 D-SLDVLYTIE----EASPFLVN-QEGLITLSGTVDYEIQMTYNLTVTATDREDTSRQGS 635

Query: 671 VIVHIKIEDINDSPPVFESDC-LTFYISENSPIGTTIG---------EIRAHDPDEGPNA 720
             V I I D+ND PP F++    +  ++E++    ++           ++A DPD   N 
Sbjct: 636 CTVMINIMDVNDEPPEFDTPSPSSLSVNESAAYCDSLPGSDDCHVLITLQATDPD--TNT 693

Query: 721 VVHYSI---KGGDDSN-----SFSLETRQGSDKAELVTMVDLDYES-PRKKYELVIRAAS 771
            + YSI   KG D+++     +FS +    S+  ++    +LD E+  R    +V+    
Sbjct: 694 DLRYSILDVKGYDENSRLVVGNFSDQFGVDSETGDVFVRTELDRETVQRFDVTVVVDDMK 753

Query: 772 PPLWNDVRVE-----ILVTDVNDNAPVMKDFQIIFNNYK-DCFPVGPFGRVPAYDADVTD 825
               ND + +     I V DVNDNAP   D    F   + D   +     + A D D  D
Sbjct: 754 AEENNDTQTDSAELVITVLDVNDNAPEFIDLPDNFTTPETDQVGMVISVNILADDEDAED 813

Query: 826 K--LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
              + Y +L  +   L+ ++ETTG +T+   ++  +    T+     DG
Sbjct: 814 NGIVIYELLD-DAGGLVAISETTGILTVKQPIDKELNDSLTITFCAKDG 861



 Score =  180 bits (438), Expect = 5e-43
 Identities = 220/812 (27%), Positives = 345/812 (42%), Gaps = 88/812 (10%)

Query: 117 VKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKA 176
           ++  D   P+ +++++  +I++ + D +DN P F+ K    +   + S     +   ++A
Sbjct: 193 IEEDDDDQPM-EQINTNTSIYIRLSDVDDNPPTFTPKGVVNATIPEHSPRGTQLDFSLEA 251

Query: 177 TDADVGANSAIRYAIIGGN------TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ 230
            D D G    I  ++          ++  F+   +   V     LD+E++      I+A 
Sbjct: 252 FDLDSGEAGRIILSLEDDEGIFYLVSETIFNSGVVDVRVDNSSALDFERISEVTFQIKAS 311

Query: 231 D--GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV 288
           D  GG+ S    T  L NI   NDN P F  S +  S+ EN      + +++A DAD  V
Sbjct: 312 DAQGGNFSVVTATVYLTNI---NDNTPVFSQSQYDVSLPENSVENTPVQQLEATDAD--V 366

Query: 289 NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD--RETQAKYQLLVTATDGGDPPR 346
            AELT+ +    Y  +      I+  +G++  S   D   E  + Y L    +DG    R
Sbjct: 367 GAELTFELL--GYNNDW---FNINSSTGYISVSDTADFNAELLSVYFLTCVVSDG---ER 418

Query: 347 SATATXXXXXXXXXXXXXXFMPG-------QYEVELAEDEPPGTPVVTLTATDADED--N 397
            +TA               F          +Y V++ E+E  G  ++ + ATDAD +  N
Sbjct: 419 VSTALLNVTVTDVNDNPPLFQLDLYSVSIPEYNVDMLEEEDEGLNILQVLATDADINVIN 478

Query: 398 R-LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK-QERRYVLTVSATDSG--GRSDTA 453
           R L Y I  GN  G+F I S    G+I     +D + +E  + + V A D G    + T 
Sbjct: 479 RMLTYSIESGNEEGKFDINSTT--GMIFRKASIDRETEEATFEMVVMAIDGGTPSMNGTT 536

Query: 454 MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513
           +V I+I D N+  P+F  A Y A V E+A  GT V  ++A D DV  +  + Y++     
Sbjct: 537 LVTISIEDVNDNNPIFLAALYNAEVPENAAFGTLVANITAVDMDVD-SLDVLYTI----- 590

Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
            EA       F++N Q G IT +  +D E    Y LTVTA D    S   +  V I+++D
Sbjct: 591 EEA-----SPFLVN-QEGLITLSGTVDYEIQMTYNLTVTATDREDTSRQGSCTVMINIMD 644

Query: 574 VNDNEPVFKQQLYTA-NIME-----DALVGTSVSQV----GATDADVGLNGRIHYELDPK 623
           VND  P F     ++ ++ E     D+L G+    V     ATD D   + R +  LD K
Sbjct: 645 VNDEPPEFDTPSPSSLSVNESAAYCDSLPGSDDCHVLITLQATDPDTNTDLR-YSILDVK 703

Query: 624 DREEGS----------FVIDPASGVIRTNKALDRESVATHDLKAVAID----GGTPPQSS 669
             +E S          F +D  +G +     LDRE+V   D+  V  D         Q+ 
Sbjct: 704 GYDENSRLVVGNFSDQFGVDSETGDVFVRTELDRETVQRFDVTVVVDDMKAEENNDTQTD 763

Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG-EIRAHDPDEGPNAVVHYSIKG 728
           +  + I + D+ND+ P F      F   E   +G  I   I A D D   N +V Y +  
Sbjct: 764 SAELVITVLDVNDNAPEFIDLPDNFTTPETDQVGMVISVNILADDEDAEDNGIVIYELL- 822

Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVN 788
            DD+    +   + +    +   +D +                PPL   V  +I +TDVN
Sbjct: 823 -DDAGGL-VAISETTGILTVKQPIDKELNDSLTITFCAKDGGDPPLNTTVTRQIFITDVN 880

Query: 789 DNAPVMKDFQIIFNNYKDCFPVGPFG----RVPAYDADVT-DKLQYRILSGNNANLILLN 843
           DN PV   F +   N          G     V A DAD     L Y I +G      ++N
Sbjct: 881 DNTPV---FNVSLPNEASILEDTTNGTLVLTVYATDADPDFGDLTYTISAGVGLEDFVIN 937

Query: 844 ETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE 875
              G +T+  +L+     L T+ V  +DG+ +
Sbjct: 938 PENGDITVQNELDREEQALYTLTVVASDGIRQ 969



 Score =  146 bits (354), Expect = 8e-33
 Identities = 165/640 (25%), Positives = 267/640 (41%), Gaps = 72/640 (11%)

Query: 7    IHQQINVLDCNDHSPVFEMQ-QYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELV 65
            + +QI + D ND++PVF +    EAS+ E  ++GT VLT+ ATD D     ++ YTI   
Sbjct: 870  VTRQIFITDVNDNTPVFNVSLPNEASILEDTTNGTLVLTVYATDAD-PDFGDLTYTISA- 927

Query: 66   TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125
                +  ED               F I+  +G +  +  LDRE+ A YT+ V A+D    
Sbjct: 928  ---GVGLED---------------FVINPENGDITVQNELDREEQALYTLTVVASDGIR- 968

Query: 126  VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN- 184
              D L  T TI    +D NDN+P+F+E     +   + +   + V A +   D + G N 
Sbjct: 969  -QDNLEVTITI----LDVNDNHPEFTESFPESTTISETAEPGSSVAAIVAVDDDEPGTNN 1023

Query: 185  SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQD-GGSPSRSNTTQ 242
            SA+RY +   N    F +D ++G V L  T     +   Y LV+ A D G  P  ++   
Sbjct: 1024 SAVRYIMTDENQSGFFKMDYVTGVVILNTTSTDALIPGVYVLVVVASDLGDPPLMTDPRN 1083

Query: 243  LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
              + + D ND AP F       +V  +      I   +A D D G N  +T+   D    
Sbjct: 1084 FSVIVTDYNDEAPVFVQPKQGATVYVDENYSGHITTAEATDGDLGDNGVVTFAF-DTGLG 1142

Query: 303  GNVDLP-ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG----GDPPRSATATXXXXXX 357
               D    TID  +G +  + + DRET+  Y  L+    G     DP RS+  T      
Sbjct: 1143 ATDDYKYFTIDETTGAIEITSETDRETKEIYIRLLLGIIGMNAKSDPIRSSQVTFYVQVN 1202

Query: 358  XXXXXXXXFMPGQYEVELAEDEPP------------GTPVVTLT-ATDADED--NRLHYE 402
                    +   +   E  +D P             GT V T+  A D D D  N+++Y 
Sbjct: 1203 DTDDNEPAYWGERTGPEGPQDPPEAALLYVQENLGEGTFVGTVPEAVDLDSDLYNQIYYF 1262

Query: 403  ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT-------------DSGGR 449
            I    +   F +   +G   +T+  P+D ++   + L + A              D    
Sbjct: 1263 IVSATSEDYFILDKYSGN--LTLVNPIDREKRPEFSLVIWADSNPDYEPDMNVIYDPLKE 1320

Query: 450  SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509
             + A V + ++D N+  P FE   YTA V      G  V+ V+A D D+G NA   Y++ 
Sbjct: 1321 DNLARVTVTVSDVNDSPPRFEEDRYTAGVLYSTSFGVEVITVNAVDPDLGENAVTVYTIL 1380

Query: 510  SEISNEAVAHHDQQ---FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566
            S+ S +A  +   +   F IN   G +  +        S Y++ + A D   P+ +D   
Sbjct: 1381 SQKSYDADGNGGVEVDVFAIN--DGKVINSVTFQASDDSYYIVELQATDSLNPNFTDNAT 1438

Query: 567  VEISVV-DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
            + + ++ ++     +F  +       +D  +      + A
Sbjct: 1439 LSVYLMTEIEQVSALFADEPVNVRETQDDFIRLPTQAIAA 1478



 Score = 41.1 bits (92), Expect = 0.43
 Identities = 20/44 (45%), Positives = 25/44 (56%)

Query: 445 DSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
           D  GR+DT  V I+I DA N  PVF   PY  S+ ED  +  T+
Sbjct: 7   DDEGRNDTTKVVISIRDAQNQPPVFIGQPYDKSIPEDTAVVHTM 50


>UniRef50_A7SN98 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 471

 Score =  272 bits (668), Expect = 7e-71
 Identities = 173/466 (37%), Positives = 252/466 (54%), Gaps = 27/466 (5%)

Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS 164
           LDRE    YT+ VKATD   PV  R S+ A ++V ++D NDN P F +++Y V + E   
Sbjct: 11  LDRETKLNYTLDVKATD-VDPVDPRWSA-AVVYVEVLDSNDNAPVFKKQSYVVEMVEHSP 68

Query: 165 VT------DNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYE 218
            T         V+  IK TD DVG+N  I Y+I+ GN    F IDS S  + +V  +D E
Sbjct: 69  TTFTVVKVGEKVVFLIKTTDRDVGSNGRISYSIVSGNVDGAFVIDS-SSVIRVVALVDRE 127

Query: 219 -QVRSYRLVIRAQDGGSPS-RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSI 276
                Y L++ A+D G P+  + T ++ I I D+NDNAPRF    +  SV E+  +G  +
Sbjct: 128 AHPAGYSLLVVARDHGYPTPNAATARVNITISDINDNAPRFLKFTYSGSVREDRTVGTEV 187

Query: 277 VRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLV 336
           V+VQA D D+G+  E+ + +T  D  G   +  T    SG +  +  LDRE +A Y+L V
Sbjct: 188 VQVQATDDDDGLAGEIVFAITGGDPEGLFSILNT----SGKITVARSLDREMKATYELTV 243

Query: 337 TATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED 396
           TATD    P+S +                F      + L+E   PGTPV+T+ ATD D  
Sbjct: 244 TATDRAGDPKSTSVEVDITITDANDNKPVFTNIPATILLSESTIPGTPVITVVATDQDIG 303

Query: 397 NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTA 453
                   G + +G+F++ +  G  +++    LD++  +RY + + ATD G     S T 
Sbjct: 304 VNGQVRYVGDSPKGKFAVNAITG--VVSTVGELDYEDVQRYTVYIVATDQGEPQLNSTTL 361

Query: 454 MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513
            + I++ DAN+  P F  A YTA V E+A  GT V++V+AT+ D G +++ITY++S+   
Sbjct: 362 HLNISLVDANDNNPTFTKAAYTAHVSEEATAGTNVIMVNATERDSGKDSKITYNISA--- 418

Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
            + + H    F IN  TG I+  K LDRET S Y L V+ARDGG P
Sbjct: 419 GDPLDH----FAINHLTGQISVRKALDRETTSLYTLLVSARDGGTP 460



 Score =  257 bits (630), Expect = 3e-66
 Identities = 175/488 (35%), Positives = 252/488 (51%), Gaps = 35/488 (7%)

Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLINIRDVNDNAPRFYTSLFQ 263
           ++GD+  V  LD E   +Y L ++A D      R +   + + + D NDNAP F    + 
Sbjct: 1   MTGDIRAVGLLDRETKLNYTLDVKATDVDPVDPRWSAAVVYVEVLDSNDNAPVFKKQSYV 60

Query: 264 ESVSENVPIGYSIVRV--------QAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315
             + E+ P  +++V+V        +  D D G N  ++Y++     +GNVD    ID  S
Sbjct: 61  VEMVEHSPTTFTVVKVGEKVVFLIKTTDRDVGSNGRISYSIV----SGNVDGAFVIDS-S 115

Query: 316 GWVYTSGQLDRETQ-AKYQLLVTATDGGDP-PRSATATXXXXXXXXXXXXXXFMPGQYEV 373
             +     +DRE   A Y LLV A D G P P +ATA               F+   Y  
Sbjct: 116 SVIRVVALVDREAHPAGYSLLVVARDHGYPTPNAATARVNITISDINDNAPRFLKFTYSG 175

Query: 374 ELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431
            + ED   GT VV + ATD D+     + + ITGG+  G FSI + +G+  ITVA+ LD 
Sbjct: 176 SVREDRTVGTEVVQVQATDDDDGLAGEIVFAITGGDPEGLFSILNTSGK--ITVARSLDR 233

Query: 432 KQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
           + +  Y LTV+ATD  G  +S +  V I ITDAN+  PVF N P T  + E    GT V+
Sbjct: 234 EMKATYELTVTATDRAGDPKSTSVEVDITITDANDNKPVFTNIPATILLSESTIPGTPVI 293

Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
            V ATD D+G+N Q+ Y   S            +F +N  TG ++T   LD E +  Y +
Sbjct: 294 TVVATDQDIGVNGQVRYVGDSPKG---------KFAVNAITGVVSTVGELDYEDVQRYTV 344

Query: 550 TVTARDGGVPSLSDTT-DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
            + A D G P L+ TT  + IS+VD NDN P F +  YTA++ E+A  GT+V  V AT+ 
Sbjct: 345 YIVATDQGEPQLNSTTLHLNISLVDANDNNPTFTKAAYTAHVSEEATAGTNVIMVNATER 404

Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ- 667
           D G + +I Y +   D  +  F I+  +G I   KALDRE+ + + L   A DGGTPP+ 
Sbjct: 405 DSGKDSKITYNISAGDPLD-HFAINHLTGQISVRKALDRETTSLYTLLVSARDGGTPPRF 463

Query: 668 -SSTVIVH 674
             +TV++H
Sbjct: 464 GQATVLIH 471



 Score =  206 bits (503), Expect = 7e-51
 Identities = 150/445 (33%), Positives = 215/445 (48%), Gaps = 31/445 (6%)

Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGGDP--PRSATATXXXXXXXXXXXXXXFMPGQYE 372
           +G +   G LDRET+  Y L V ATD  DP  PR + A               F    Y 
Sbjct: 2   TGDIRAVGLLDRETKLNYTLDVKATDV-DPVDPRWSAAVVYVEVLDSNDNAPVFKKQSYV 60

Query: 373 VELAEDEPP-------GTPVVTLTAT---DADEDNRLHYEITGGNTRGRFSITSQNGRGL 422
           VE+ E  P        G  VV L  T   D   + R+ Y I  GN  G F I S +   +
Sbjct: 61  VEMVEHSPTTFTVVKVGEKVVFLIKTTDRDVGSNGRISYSIVSGNVDGAFVIDSSS---V 117

Query: 423 ITVAQPLDFKQERR-YVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASV 478
           I V   +D +     Y L V A D G     + TA V I I+D N+ AP F    Y+ SV
Sbjct: 118 IRVVALVDREAHPAGYSLLVVARDHGYPTPNAATARVNITISDINDNAPRFLKFTYSGSV 177

Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
            ED  +GT V+ V ATD D G+  +I ++++           +  F I   +G IT  + 
Sbjct: 178 REDRTVGTEVVQVQATDDDDGLAGEIVFAITG-------GDPEGLFSILNTSGKITVARS 230

Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
           LDRE  + Y LTVTA D      S + +V+I++ D NDN+PVF     T  + E  + GT
Sbjct: 231 LDREMKATYELTVTATDRAGDPKSTSVEVDITITDANDNKPVFTNIPATILLSESTIPGT 290

Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
            V  V ATD D+G+NG++ Y     D  +G F ++  +GV+ T   LD E V  + +  V
Sbjct: 291 PVITVVATDQDIGVNGQVRY---VGDSPKGKFAVNAITGVVSTVGELDYEDVQRYTVYIV 347

Query: 659 AIDGGTPPQSSTVI-VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
           A D G P  +ST + ++I + D ND+ P F     T ++SE +  GT +  + A + D G
Sbjct: 348 ATDQGEPQLNSTTLHLNISLVDANDNNPTFTKAAYTAHVSEEATAGTNVIMVNATERDSG 407

Query: 718 PNAVVHYSIKGGDDSNSFSLETRQG 742
            ++ + Y+I  GD  + F++    G
Sbjct: 408 KDSKITYNISAGDPLDHFAINHLTG 432



 Score =  190 bits (462), Expect = 6e-46
 Identities = 153/463 (33%), Positives = 224/463 (48%), Gaps = 35/463 (7%)

Query: 429 LDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
           LD + +  Y L V ATD      R   A+V + + D+N+ APVF+   Y   + E +P  
Sbjct: 11  LDRETKLNYTLDVKATDVDPVDPRWSAAVVYVEVLDSNDNAPVFKKQSYVVEMVEHSPTT 70

Query: 486 TTVL--------VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            TV+        ++  TD DVG N +I+YS+ S        + D  FVI+  +  I    
Sbjct: 71  FTVVKVGEKVVFLIKTTDRDVGSNGRISYSIVS-------GNVDGAFVID-SSSVIRVVA 122

Query: 538 LLDRETM-SGYLLTVTARDGGVPSLSDTTD-VEISVVDVNDNEPVFKQQLYTANIMEDAL 595
           L+DRE   +GY L V ARD G P+ +  T  V I++ D+NDN P F +  Y+ ++ ED  
Sbjct: 123 LVDREAHPAGYSLLVVARDHGYPTPNAATARVNITISDINDNAPRFLKFTYSGSVREDRT 182

Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655
           VGT V QV ATD D GL G I + +   D  EG F I   SG I   ++LDRE  AT++L
Sbjct: 183 VGTEVVQVQATDDDDGLAGEIVFAITGGD-PEGLFSILNTSGKITVARSLDREMKATYEL 241

Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
              A D    P+S++V V I I D ND+ PVF +   T  +SE++  GT +  + A D D
Sbjct: 242 TVTATDRAGDPKSTSVEVDITITDANDNKPVFTNIPATILLSESTIPGTPVITVVATDQD 301

Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP--P 773
            G N  V Y   G      F++    G     + T+ +LDYE  ++ Y + I A     P
Sbjct: 302 IGVNGQVRYV--GDSPKGKFAVNAITGV----VSTVGELDYEDVQR-YTVYIVATDQGEP 354

Query: 774 LWND--VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQY 829
             N   + + I + D NDN P         +  ++         V A + D     K+ Y
Sbjct: 355 QLNSTTLHLNISLVDANDNNPTFTKAAYTAHVSEEATAGTNVIMVNATERDSGKDSKITY 414

Query: 830 RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
            I +G+  +   +N  TG +++   L+     L T+ VS  DG
Sbjct: 415 NISAGDPLDHFAINHLTGQISVRKALDRETTSLYTLLVSARDG 457



 Score =  180 bits (439), Expect = 4e-43
 Identities = 138/449 (30%), Positives = 215/449 (47%), Gaps = 44/449 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT--------LKATDQDIGKNAEVEYTI 62
           + VLD ND++PVF+ Q Y   + E + +  TV+         +K TD+D+G N  + Y+I
Sbjct: 42  VEVLDSNDNAPVFKKQSYVVEMVEHSPTTFTVVKVGEKVVFLIKTTDRDVGSNGRISYSI 101

Query: 63  ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREK-VARYTVLVKATD 121
                                  V   F ID  S  +   A +DRE   A Y++LV A D
Sbjct: 102 -------------------VSGNVDGAFVIDS-SSVIRVVALVDREAHPAGYSLLVVARD 141

Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181
              P  +  ++TA +++ I D NDN P+F + TY+ SV ED +V     + +++ATD D 
Sbjct: 142 HGYPTPN--AATARVNITISDINDNAPRFLKFTYSGSVREDRTVGTE--VVQVQATDDDD 197

Query: 182 GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
           G    I +AI GG+ +  FSI + SG +++ ++LD E   +Y L + A D     +S + 
Sbjct: 198 GLAGEIVFAITGGDPEGLFSILNTSGKITVARSLDREMKATYELTVTATDRAGDPKSTSV 257

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
           ++ I I D NDN P F        +SE+   G  ++ V A D D GVN ++ Y       
Sbjct: 258 EVDITITDANDNKPVFTNIPATILLSESTIPGTPVITVVATDQDIGVNGQVRY--VGDSP 315

Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP-RSATATXXXXXXXXX 360
            G       ++  +G V T G+LD E   +Y + + ATD G+P   S T           
Sbjct: 316 KGK----FAVNAITGVVSTVGELDYEDVQRYTVYIVATDQGEPQLNSTTLHLNISLVDAN 371

Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQN 418
                F    Y   ++E+   GT V+ + AT+ D  +D+++ Y I+ G+    F+I    
Sbjct: 372 DNNPTFTKAAYTAHVSEEATAGTNVIMVNATERDSGKDSKITYNISAGDPLDHFAINHLT 431

Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSG 447
           G+  I+V + LD +    Y L VSA D G
Sbjct: 432 GQ--ISVRKALDRETTSLYTLLVSARDGG 458



 Score =  178 bits (433), Expect = 2e-42
 Identities = 120/342 (35%), Positives = 180/342 (52%), Gaps = 31/342 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I + D ND++P F    Y  SVRE  + GT V+ ++ATD D G   E+ + I   T    
Sbjct: 156 ITISDINDNAPRFLKFTYSGSVREDRTVGTEVVQVQATDDDDGLAGEIVFAI---TGG-- 210

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           +PE               +F I   SG +    SLDRE  A Y + V ATD+A    D  
Sbjct: 211 DPEG--------------LFSILNTSGKITVARSLDREMKATYELTVTATDRAG---DPK 253

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           S++  + + I D NDN P F+    T+ + E  ++   PVI  + ATD D+G N  +RY 
Sbjct: 254 STSVEVDITITDANDNKPVFTNIPATILLSES-TIPGTPVITVV-ATDQDIGVNGQVRY- 310

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT-QLLINIRD 249
            +G + + +F++++++G VS V  LDYE V+ Y + I A D G P  ++TT  L I++ D
Sbjct: 311 -VGDSPKGKFAVNAITGVVSTVGELDYEDVQRYTVYIVATDQGEPQLNSTTLHLNISLVD 369

Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            NDN P F  + +   VSE    G +++ V A + D G ++++TY ++  D   +     
Sbjct: 370 ANDNNPTFTKAAYTAHVSEEATAGTNVIMVNATERDSGKDSKITYNISAGDPLDH----F 425

Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
            I+  +G +     LDRET + Y LLV+A DGG PPR   AT
Sbjct: 426 AINHLTGQISVRKALDRETTSLYTLLVSARDGGTPPRFGQAT 467



 Score =  153 bits (371), Expect = 7e-35
 Identities = 119/356 (33%), Positives = 170/356 (47%), Gaps = 21/356 (5%)

Query: 530 TGAITTNKLLDRETMSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588
           TG I    LLDRET   Y L V A D   V        V + V+D NDN PVFK+Q Y  
Sbjct: 2   TGDIRAVGLLDRETKLNYTLDVKATDVDPVDPRWSAAVVYVEVLDSNDNAPVFKKQSYVV 61

Query: 589 NIMEDALVGTSVSQVG--------ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640
            ++E +    +V +VG         TD DVG NGRI Y +      +G+FVID +S VIR
Sbjct: 62  EMVEHSPTTFTVVKVGEKVVFLIKTTDRDVGSNGRISYSI-VSGNVDGAFVID-SSSVIR 119

Query: 641 TNKALDRES-VATHDLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698
               +DRE+  A + L  VA D G P P ++T  V+I I DIND+ P F     +  + E
Sbjct: 120 VVALVDREAHPAGYSLLVVARDHGYPTPNAATARVNITISDINDNAPRFLKFTYSGSVRE 179

Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758
           +  +GT + +++A D D+G    + ++I GGD    FS+    G    ++     LD E 
Sbjct: 180 DRTVGTEVVQVQATDDDDGLAGEIVFAITGGDPEGLFSILNTSG----KITVARSLDREM 235

Query: 759 PRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR 815
            +  YEL + A   A  P    V V+I +TD NDN PV  +        +   P  P   
Sbjct: 236 -KATYELTVTATDRAGDPKSTSVEVDITITDANDNKPVFTNIPATILLSESTIPGTPVIT 294

Query: 816 VPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
           V A D D+    Q R +  +      +N  TG ++   +L+    +  T+ +  TD
Sbjct: 295 VVATDQDIGVNGQVRYVGDSPKGKFAVNAITGVVSTVGELDYEDVQRYTVYIVATD 350



 Score =  129 bits (311), Expect = 1e-27
 Identities = 85/242 (35%), Positives = 126/242 (52%), Gaps = 29/242 (11%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           +   I + D ND+ PVF        + E    GT V+T+ ATDQDIG N +V Y  +   
Sbjct: 257 VEVDITITDANDNKPVFTNIPATILLSESTIPGTPVITVVATDQDIGVNGQVRYVGD--- 313

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
               +P+                F ++  +G + T   LD E V RYTV + ATDQ  P 
Sbjct: 314 ----SPKGK--------------FAVNAITGVVSTVGELDYEDVQRYTVYIVATDQGEP- 354

Query: 127 SDRLSSTATIHVNI--IDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184
             +L+ST T+H+NI  +D NDN P F++  YT  V E+ +   N ++  + AT+ D G +
Sbjct: 355 --QLNST-TLHLNISLVDANDNNPTFTKAAYTAHVSEEATAGTNVIM--VNATERDSGKD 409

Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
           S I Y I  G+    F+I+ L+G +S+ K LD E    Y L++ A+DGG+P R     +L
Sbjct: 410 SKITYNISAGDPLDHFAINHLTGQISVRKALDRETTSLYTLLVSARDGGTPPRFGQATVL 469

Query: 245 IN 246
           I+
Sbjct: 470 IH 471



 Score = 80.6 bits (190), Expect = 6e-13
 Identities = 70/257 (27%), Positives = 119/257 (46%), Gaps = 18/257 (7%)

Query: 636 SGVIRTNKALDRESVATH--DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693
           +G IR    LDRE+   +  D+KA  +D    P+ S  +V++++ D ND+ PVF+     
Sbjct: 2   TGDIRAVGLLDRETKLNYTLDVKATDVDP-VDPRWSAAVVYVEVLDSNDNAPVFKKQSYV 60

Query: 694 FYISENSPIGTTI---GE-----IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745
             + E+SP   T+   GE     I+  D D G N  + YSI  G+   +F +++   S  
Sbjct: 61  VEMVEHSPTTFTVVKVGEKVVFLIKTTDRDVGSNGRISYSIVSGNVDGAFVIDS---SSV 117

Query: 746 AELVTMVDLDYESPRKKYELVIRAASPPLWN--DVRVEILVTDVNDNAPVMKDFQIIFNN 803
             +V +VD +         +V R    P  N    RV I ++D+NDNAP    F    + 
Sbjct: 118 IRVVALVDREAHPAGYSLLVVARDHGYPTPNAATARVNITISDINDNAPRFLKFTYSGSV 177

Query: 804 YKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPK 861
            +D        +V A D D  +  ++ + I  G+   L  +  T+G +T++  L+  +  
Sbjct: 178 REDRTVGTEVVQVQATDDDDGLAGEIVFAITGGDPEGLFSILNTSGKITVARSLDREMKA 237

Query: 862 LATMEVSVTDGVNEIKA 878
              + V+ TD   + K+
Sbjct: 238 TYELTVTATDRAGDPKS 254


>UniRef50_UPI0000DB71FC Cluster: PREDICTED: similar to Cad87A
            CG6977-PA; n=2; Endopterygota|Rep: PREDICTED: similar to
            Cad87A CG6977-PA - Apis mellifera
          Length = 1907

 Score =  272 bits (667), Expect = 9e-71
 Identities = 274/915 (29%), Positives = 410/915 (44%), Gaps = 114/915 (12%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I + D N+++PVF  + Y AS+ E +  GT V  + ATD D G NAE+ Y I+    D  
Sbjct: 677  ITIRDVNNNAPVFPHELYTASLPEISPIGTVVEEVTATDADTGINAELVYRIQKGAFDD- 735

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F I+  +G +     LD +    Y V V A D+ +P    L
Sbjct: 736  -------------------FTINETTGIVTVFRKLDYDNKNTYHVEVIAFDKGTP---SL 773

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            + T T+ +N+ + ND  P F+ +T    V ED  +    V   +KATD D     A+ +A
Sbjct: 774  TGTTTLMINVENSNDKAPYFTPETQRAEVTEDTPI--GTVFTTLKATDPDSTNVEALNFA 831

Query: 191  I------IGGNTQMQ---------FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP 235
            I      I  N Q           F++D  +G VS+V++LD +   +  + +   D  +P
Sbjct: 832  ISEPITAIDRNGQQVNDSKSFKDFFAVDRATGQVSVVRSLDRDIAATVSITVVVSDTTAP 891

Query: 236  S-RSNTTQLLINIRDVNDNAPRFYTSLFQES------VSENVPIGYSIVRVQAYDADEGV 288
            + +     L++ I DVN  AP F     +E+      + E  P G  +    A DAD  +
Sbjct: 892  TLQQGRGTLVVTIIDVNHMAPEFLKPWTRENPRYLIEMQEEQPTGAIVGAFTAVDADSNI 951

Query: 289  NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348
                 Y +       N+D  +T     G V TS  +D E   + +  V A D G P  SA
Sbjct: 952  AG---YAIIPPSPYFNID-NVT-----GIVRTSQVIDYEETKQLEFTVVAYDSGVPQLSA 1002

Query: 349  TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGG 406
            T                F    Y   + E+ PPGT V+ + ATD DE     + Y + G 
Sbjct: 1003 TTKVIVTVININDQDPKFEKELYNASVKENSPPGTHVIVVKATDGDEGPFGEVSYSLIGD 1062

Query: 407  NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD----SGGRSDTAMVQINITDA 462
            +    F+I  + G   +  A  LD +      +TV A+D    +  RS T  V + + D 
Sbjct: 1063 HAAD-FNIGHETGEITVGSAAVLDREITPNITITVMASDGAHINSRRSTTVPVVVKLIDV 1121

Query: 463  NNYAPVFENAPYTASVFEDAPIG--TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520
            N+  P+F    Y ASV E+ P+     +L V A D D GIN ++ Y++     NE+    
Sbjct: 1122 NDNRPIFTQHSYRASVAENLPVNPPAPILQVRAVDHDEGINGEVWYTIIHGNENES---- 1177

Query: 521  DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEP 579
               F +N +TG +     L     S Y + V ARDG G    SD   V+I V  VN ++P
Sbjct: 1178 ---FSLNHETGILYPGAALLGRAGS-YRIEVEARDGAGNGPHSDKCYVDIRVTPVNQHKP 1233

Query: 580  VFKQQLYTANIME----DALVGTSVSQVGATDADVGLNGRIHYELDPKDR---EEGSFVI 632
             F     T   +E      ++   +  V A D D G NGR+ Y L   +R   E   F I
Sbjct: 1234 QFVLPELTNATVEVPENTGVLNYLILTVKAIDRDPGENGRVSYHLKVGNRNIQETEEFSI 1293

Query: 633  DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV-IVHIKIEDINDSPPVFESDC 691
            D  +G +R+   LDRE  +  +L  VA D GTP    T+ ++ +++ D ND+ P F  + 
Sbjct: 1294 DQETGELRSKIILDREVKSKFELVLVAADHGTPTAYETLRLLTVQLVDTNDNTPQFYDE- 1352

Query: 692  LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751
              F ISEN P    +G++ A D DEG +A V+Y I+ G+++ +F ++   GS    + T 
Sbjct: 1353 YHFQISENRPKDYFVGKVIAEDKDEGRHAKVYYYIEAGNENYAFYIDKSDGS----IYTN 1408

Query: 752  VDLDYESPRKKYELVIRAA-------SP-----PLWND-----VRVEILVTDVNDNAPVM 794
               D E+ R KY L I A+       SP     PL ++     V V I++ D NDN+P+ 
Sbjct: 1409 KSFDRET-RDKYVLSILASNDPDIYISPADAGRPLMHNTDHGYVNVTIIILDENDNSPIF 1467

Query: 795  K--DFQIIFNNYKDCFPVGPF-GRVPAYDADVTDK--LQYRILSGNNANLILLNETTGSM 849
            +  D+    N+  +   V  F  +V A D DV D   L Y + S  N       + +GS+
Sbjct: 1468 ERNDYYAGVNSMAN---VNDFVTKVTASDLDVGDNGTLHYYVASA-NLYKYGSEKPSGSI 1523

Query: 850  TLSPQLNTNVPKLAT 864
              SP + T   KL T
Sbjct: 1524 VPSPFIVTQDGKLVT 1538



 Score =  252 bits (616), Expect = 1e-64
 Identities = 239/834 (28%), Positives = 384/834 (46%), Gaps = 94/834 (11%)

Query: 13  VLDCNDHSPVFEMQQYEASVREGASSGTTVLT-LKATDQDIGKNAEVEYTIELVTADTLN 71
           VLD ND+ P F    YEA   E    G+T+L+ +K  D D+     +  TI+L    T  
Sbjct: 119 VLDDNDNPPRFLNVPYEAVAEEDLPVGSTILSGIKVIDPDL-----LGDTIDL----TCV 169

Query: 72  PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131
           P+            V    R +  +GAL+ R  LD  +   Y +L++A+D  +      +
Sbjct: 170 PQPQFLDACEKFGIVDVEKRQNSYTGALVLRQPLDYRERPFYQLLLRASDGLN------N 223

Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191
            T  + + + D  ++ P+F + + T  V ED  +    ++  +KA D D G    + Y +
Sbjct: 224 ETTGVEIKVADIQNSPPEFLD-SLTGVVREDDPI--GTLVMTVKARDGDRGMPRKMIYEL 280

Query: 192 IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS----YRLVIRAQD--GGSPSRSN----TT 241
           +  N    F +D  +G++   K L+ E ++       L +RA++   G P   N    T 
Sbjct: 281 V-TNPFDYFLLDDETGELRTAKPLNREALKDSTGVLTLKVRARELIDGMPGNDNLTVSTA 339

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
           +  + I+DVND  P F    +   + ENVP G  +  +     D  V     +++  +D 
Sbjct: 340 EATVTIKDVNDEPPTFNRREYNIEIPENVPNGTPLPHLDMTVKDPDVGLNSVFSLRLEDI 399

Query: 302 TGNVDLPITIDPRSGWVYTS-------GQLDRE--TQAKYQLLVTATD-GGDPPRSATAT 351
           T   D   TI+P      TS       G LD E   Q K+ +LV A +   DP  S+TAT
Sbjct: 400 T---DGAFTIEPTMATGSTSVNIRVANGSLDYENPNQRKFIILVVAEEVHTDPKLSSTAT 456

Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN----RLHYEITGGN 407
                         F    Y   + E  PPGTPV+T+TA D D        + Y++ G  
Sbjct: 457 VTVSITDANDNSPTFSNPTYTAVVLETAPPGTPVITITAKDRDSGRFGTAGIAYQLLGQG 516

Query: 408 TRGRFSITSQNGRGLITV---AQP-----LDFKQERRYVLTVSATDSGGRSDTAMV--QI 457
            +  FS+  ++  G+ITV   A P     LD++++  Y LT  ATD  G+  T  V  +I
Sbjct: 517 AQ-HFSVDRKS--GIITVAPCANPGTSPCLDYEEQTEYFLTYKATDDDGQGQTTSVSLRI 573

Query: 458 NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517
           +++DAN+  P F    Y A + E A      L V A D D    ++ITY++   +  + +
Sbjct: 574 SLSDANDSPPRFLQDKYRAVIDEGAEKFEPDLKVQARDKDK--TSKITYAI---VGGDEL 628

Query: 518 AHHDQQFVINPQTGAIT-TNK---LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
                 F I+  TG IT  NK    L   T     L + A DG      D+  V I++ D
Sbjct: 629 ----DLFAIDQDTGEITIKNKGPVDLTNSTHDWIALVIQASDG---IFVDSAIVNITIRD 681

Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633
           VN+N PVF  +LYTA++ E + +GT V +V ATDAD G+N  + Y +     ++  F I+
Sbjct: 682 VNNNAPVFPHELYTASLPEISPIGTVVEEVTATDADTGINAELVYRIQKGAFDD--FTIN 739

Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693
             +G++   + LD ++  T+ ++ +A D GTP  + T  + I +E+ ND  P F  +   
Sbjct: 740 ETTGIVTVFRKLDYDNKNTYHVEVIAFDKGTPSLTGTTTLMINVENSNDKAPYFTPETQR 799

Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI--------KGG---DDSNSFS--LETR 740
             ++E++PIGT    ++A DPD      ++++I        + G   +DS SF       
Sbjct: 800 AEVTEDTPIGTVFTTLKATDPDSTNVEALNFAISEPITAIDRNGQQVNDSKSFKDFFAVD 859

Query: 741 QGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVT--DVNDNAP 792
           + + +  +V  +D D  +      +V+   + P     R  ++VT  DVN  AP
Sbjct: 860 RATGQVSVVRSLDRDI-AATVSITVVVSDTTAPTLQQGRGTLVVTIIDVNHMAP 912



 Score =  246 bits (601), Expect = 9e-63
 Identities = 260/918 (28%), Positives = 405/918 (44%), Gaps = 96/918 (10%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I V D  +  P F +      VRE    GT V+T+KA D D G   ++ Y  ELVT   
Sbjct: 229  EIKVADIQNSPPEF-LDSLTGVVREDDPIGTLVMTVKARDGDRGMPRKMIY--ELVT--- 282

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR----YTVLVKATD--QA 123
             NP D               F +D  +G L T   L+RE +       T+ V+A +    
Sbjct: 283  -NPFD--------------YFLLDDETGELRTAKPLNREALKDSTGVLTLKVRARELIDG 327

Query: 124  SPVSDRLS-STATIHVNIIDDNDNYPQFSEKTYTVSVDEDI-SVTDNPVIAKIKATDADV 181
             P +D L+ STA   V I D ND  P F+ + Y + + E++ + T  P +  +   D DV
Sbjct: 328  MPGNDNLTVSTAEATVTIKDVNDEPPTFNRREYNIEIPENVPNGTPLPHL-DMTVKDPDV 386

Query: 182  GANS--AIRYAII--GGNT-QMQFSIDSLSGDVSLVK-TLDYEQVRSYR---LVIRAQDG 232
            G NS  ++R   I  G  T +   +  S S ++ +   +LDYE     +   LV+  +  
Sbjct: 387  GLNSVFSLRLEDITDGAFTIEPTMATGSTSVNIRVANGSLDYENPNQRKFIILVVAEEVH 446

Query: 233  GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV--NA 290
              P  S+T  + ++I D NDN+P F    +   V E  P G  ++ + A D D G    A
Sbjct: 447  TDPKLSSTATVTVSITDANDNSPTFSNPTYTAVVLETAPPGTPVITITAKDRDSGRFGTA 506

Query: 291  ELTYTMTDKDYTG-NVDLP---ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR 346
             + Y +  +     +VD     IT+ P +    TS  LD E Q +Y L   ATD     +
Sbjct: 507  GIAYQLLGQGAQHFSVDRKSGIITVAPCAN-PGTSPCLDYEEQTEYFLTYKATDDDGQGQ 565

Query: 347  SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG 406
            + + +              F+  +Y   + E      P + + A D D+ +++ Y I GG
Sbjct: 566  TTSVSLRISLSDANDSPPRFLQDKYRAVIDEGAEKFEPDLKVQARDKDKTSKITYAIVGG 625

Query: 407  NTRGRFSITSQNGRGLITVAQPLDFKQERR--YVLTVSATDSGGRSDTAMVQINITDANN 464
            +    F+I    G   I    P+D          L + A+D G   D+A+V I I D NN
Sbjct: 626  DELDLFAIDQDTGEITIKNKGPVDLTNSTHDWIALVIQASD-GIFVDSAIVNITIRDVNN 684

Query: 465  YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524
             APVF +  YTAS+ E +PIGT V  V+ATD+D GINA++ Y +     ++        F
Sbjct: 685  NAPVFPHELYTASLPEISPIGTVVEEVTATDADTGINAELVYRIQKGAFDD--------F 736

Query: 525  VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584
             IN  TG +T  + LD +  + Y + V A D G PSL+ TT + I+V + ND  P F  +
Sbjct: 737  TINETTGIVTVFRKLDYDNKNTYHVEVIAFDKGTPSLTGTTTLMINVENSNDKAPYFTPE 796

Query: 585  LYTANIMEDALVGTSVSQVGATDAD----VGLNGRIHYELDPKDRE----------EGSF 630
               A + ED  +GT  + + ATD D      LN  I   +   DR           +  F
Sbjct: 797  TQRAEVTEDTPIGTVFTTLKATDPDSTNVEALNFAISEPITAIDRNGQQVNDSKSFKDFF 856

Query: 631  VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP-QSSTVIVHIKIEDINDSPPVF-- 687
             +D A+G +   ++LDR+  AT  +  V  D   P  Q     + + I D+N   P F  
Sbjct: 857  AVDRATGQVSVVRSLDRDIAATVSITVVVSDTTAPTLQQGRGTLVVTIIDVNHMAPEFLK 916

Query: 688  ----ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
                E+      + E  P G  +G   A D D     +  Y+I     S  F+++   G 
Sbjct: 917  PWTRENPRYLIEMQEEQPTGAIVGAFTAVDADSN---IAGYAII--PPSPYFNIDNVTGI 971

Query: 744  DKAELVTMVDLDYESPRKKYELVIRAAS--PPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801
             +   V    +DYE  ++    V+   S  P L    +V + V ++ND  P  +  ++  
Sbjct: 972  VRTSQV----IDYEETKQLEFTVVAYDSGVPQLSATTKVIVTVININDQDPKFEK-ELYN 1026

Query: 802  NNYKDCFPVGPFG-RVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTL--SPQLN 856
             + K+  P G     V A D D     ++ Y ++ G++A    +   TG +T+  +  L+
Sbjct: 1027 ASVKENSPPGTHVIVVKATDGDEGPFGEVSYSLI-GDHAADFNIGHETGEITVGSAAVLD 1085

Query: 857  TNVPKLATMEVSVTDGVN 874
              +    T+ V  +DG +
Sbjct: 1086 REITPNITITVMASDGAH 1103



 Score =  216 bits (528), Expect = 6e-54
 Identities = 212/744 (28%), Positives = 328/744 (44%), Gaps = 58/744 (7%)

Query: 88  DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
           D F ++ R+G +     LDRE+       V   D+              +V ++DDNDN 
Sbjct: 67  DHFVVNPRTGVITLAKPLDREENGTIRFRVTLEDEVPAGQQPNIVGVDAYVIVLDDNDNP 126

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG----------GNTQ 197
           P+F    Y    +ED+ V  + +++ IK  D D+  ++     +            G   
Sbjct: 127 PRFLNVPYEAVAEEDLPV-GSTILSGIKVIDPDLLGDTIDLTCVPQPQFLDACEKFGIVD 185

Query: 198 MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF 257
           ++   +S +G + L + LDY +   Y+L++RA DG     + TT + I + D+ ++ P F
Sbjct: 186 VEKRQNSYTGALVLRQPLDYRERPFYQLLLRASDG---LNNETTGVEIKVADIQNSPPEF 242

Query: 258 YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317
             SL    V E+ PIG  ++ V+A D D G+  ++ Y +     T   D    +D  +G 
Sbjct: 243 LDSL-TGVVREDDPIGTLVMTVKARDGDRGMPRKMIYELV----TNPFDY-FLLDDETGE 296

Query: 318 VYTSGQLDRET----------QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
           + T+  L+RE           + + + L+    G D    +TA               F 
Sbjct: 297 LRTAKPLNREALKDSTGVLTLKVRARELIDGMPGNDNLTVSTAEATVTIKDVNDEPPTFN 356

Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT---GGNTRGRFSITSQNGRGL-- 422
             +Y +E+ E+ P GTP+  L  T  D D  L+   +      T G F+I      G   
Sbjct: 357 RREYNIEIPENVPNGTPLPHLDMTVKDPDVGLNSVFSLRLEDITDGAFTIEPTMATGSTS 416

Query: 423 --ITVAQ-PLDFK--QERRYVLTVSATD---SGGRSDTAMVQINITDANNYAPVFENAPY 474
             I VA   LD++   +R++++ V A +       S TA V ++ITDAN+ +P F N  Y
Sbjct: 417 VNIRVANGSLDYENPNQRKFIILVVAEEVHTDPKLSSTATVTVSITDANDNSPTFSNPTY 476

Query: 475 TASVFEDAPIGTTVLVVSATDSDVGI--NAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
           TA V E AP GT V+ ++A D D G    A I Y L  + +           +       
Sbjct: 477 TAVVLETAPPGTPVITITAKDRDSGRFGTAGIAYQLLGQGAQHFSVDRKSGIITVAPCAN 536

Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592
             T+  LD E  + Y LT  A D      + +  + IS+ D ND+ P F Q  Y A I E
Sbjct: 537 PGTSPCLDYEEQTEYFLTYKATDDDGQGQTTSVSLRISLSDANDSPPRFLQDKYRAVIDE 596

Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR-TNKALDRESVA 651
            A       +V A D D     +I Y +   D E   F ID  +G I   NK     + +
Sbjct: 597 GAEKFEPDLKVQARDKD--KTSKITYAIVGGD-ELDLFAIDQDTGEITIKNKGPVDLTNS 653

Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711
           THD  A+ I         + IV+I I D+N++ PVF  +  T  + E SPIGT + E+ A
Sbjct: 654 THDWIALVIQASDGIFVDSAIVNITIRDVNNNAPVFPHELYTASLPEISPIGTVVEEVTA 713

Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVIR-- 768
            D D G NA + Y I+ G   + F++    G     +VT+   LDY++    +  VI   
Sbjct: 714 TDADTGINAELVYRIQKG-AFDDFTINETTG-----IVTVFRKLDYDNKNTYHVEVIAFD 767

Query: 769 AASPPLWNDVRVEILVTDVNDNAP 792
             +P L     + I V + ND AP
Sbjct: 768 KGTPSLTGTTTLMINVENSNDKAP 791



 Score =  187 bits (456), Expect = 3e-45
 Identities = 163/595 (27%), Positives = 268/595 (45%), Gaps = 54/595 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V++ ND  P FE + Y ASV+E +  GT V+ +KATD D G   EV Y++       +
Sbjct: 1008 VTVININDQDPKFEKELYNASVKENSPPGTHVIVVKATDGDEGPFGEVSYSL-------I 1060

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALL--TRASLDREKVARYTVLVKATDQASPVSD 128
                A              F I   +G +   + A LDRE     T+ V A+D A  ++ 
Sbjct: 1061 GDHAAD-------------FNIGHETGEITVGSAAVLDREITPNITITVMASDGAH-INS 1106

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            R S+T  + V +ID NDN P F++ +Y  SV E++ V     I +++A D D G N  + 
Sbjct: 1107 RRSTTVPVVVKLIDVNDNRPIFTQHSYRASVAENLPVNPPAPILQVRAVDHDEGINGEVW 1166

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG-GSPSRSNTTQLLINI 247
            Y II GN    FS++  +G +     L   +  SYR+ + A+DG G+   S+   + I +
Sbjct: 1167 YTIIHGNENESFSLNHETGILYPGAAL-LGRAGSYRIEVEARDGAGNGPHSDKCYVDIRV 1225

Query: 248  RDVNDNAPRFYTSLFQES---VSENVPI-GYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
              VN + P+F       +   V EN  +  Y I+ V+A D D G N  ++Y +   +   
Sbjct: 1226 TPVNQHKPQFVLPELTNATVEVPENTGVLNYLILTVKAIDRDPGENGRVSYHLKVGNRNI 1285

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
                  +ID  +G + +   LDRE ++K++L++ A D G P    T              
Sbjct: 1286 QETEEFSIDQETGELRSKIILDREVKSKFELVLVAADHGTPTAYETLRLLTVQLVDTNDN 1345

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRG 421
                  +Y  +++E+ P    V  + A D DE    +++Y I  GN    F I   +G  
Sbjct: 1346 TPQFYDEYHFQISENRPKDYFVGKVIAEDKDEGRHAKVYYYIEAGNENYAFYIDKSDGS- 1404

Query: 422  LITVAQPLDFKQERRYVLTVSATDS---------GGRS---DTAMVQINIT----DANNY 465
             I   +  D +   +YVL++ A++           GR    +T    +N+T    D N+ 
Sbjct: 1405 -IYTNKSFDRETRDKYVLSILASNDPDIYISPADAGRPLMHNTDHGYVNVTIIILDENDN 1463

Query: 466  APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL-SSEISNEAVAHHDQQF 524
            +P+FE   Y A V   A +   V  V+A+D DVG N  + Y + S+ +            
Sbjct: 1464 SPIFERNDYYAGVNSMANVNDFVTKVTASDLDVGDNGTLHYYVASANLYKYGSEKPSGSI 1523

Query: 525  VINP----QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575
            V +P    Q G + T+  +       +++ V A++  +P     T V + V + +
Sbjct: 1524 VPSPFIVTQDGKLVTSGYMAEYNQDRFIVEVIAKEAAIPERYAMTRVHVWVFEAS 1578



 Score =  180 bits (437), Expect = 7e-43
 Identities = 196/715 (27%), Positives = 315/715 (44%), Gaps = 59/715 (8%)

Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD----GGSPSRSNTTQLLINIRDVNDNAP 255
           F ++  +G ++L K LD E+  + R  +  +D    G  P+       +I + D NDN P
Sbjct: 69  FVVNPRTGVITLAKPLDREENGTIRFRVTLEDEVPAGQQPNIVGVDAYVI-VLDDNDNPP 127

Query: 256 RFYTSLFQESVSENVPIGYSIVR-VQAYDAD-EGVNAELTYTMTDK-----DYTGNVDLP 308
           RF    ++    E++P+G +I+  ++  D D  G   +LT     +     +  G VD+ 
Sbjct: 128 RFLNVPYEAVAEEDLPVGSTILSGIKVIDPDLLGDTIDLTCVPQPQFLDACEKFGIVDVE 187

Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
              +  +G +     LD   +  YQLL+ A+DG     + T                F+ 
Sbjct: 188 KRQNSYTGALVLRQPLDYRERPFYQLLLRASDG---LNNETTGVEIKVADIQNSPPEFLD 244

Query: 369 GQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
               V + ED+P GT V+T+ A D D     ++ YE+   N    F +  + G   +  A
Sbjct: 245 SLTGV-VREDDPIGTLVMTVKARDGDRGMPRKMIYELV-TNPFDYFLLDDETGE--LRTA 300

Query: 427 QPLDFK--QERRYVLTVSA-----TDSGGRSD-----TAMVQINITDANNYAPVFENAPY 474
           +PL+ +  ++   VLT+        D    +D     TA   + I D N+  P F    Y
Sbjct: 301 KPLNREALKDSTGVLTLKVRARELIDGMPGNDNLTVSTAEATVTIKDVNDEPPTFNRREY 360

Query: 475 TASVFEDAPIGTTV--LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
              + E+ P GT +  L ++  D DVG+N+  +  L  +I++ A          +     
Sbjct: 361 NIEIPENVPNGTPLPHLDMTVKDPDVGLNSVFSLRL-EDITDGAFTIEPTMATGSTSVNI 419

Query: 533 ITTNKLLDRE--TMSGYLLTVTARDGGV-PSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589
              N  LD E      +++ V A +    P LS T  V +S+ D NDN P F    YTA 
Sbjct: 420 RVANGSLDYENPNQRKFIILVVAEEVHTDPKLSSTATVTVSITDANDNSPTFSNPTYTAV 479

Query: 590 IMEDALVGTSVSQVGATDADVGLNGR--IHYELDPKDREEGSFVIDPASGVIR------- 640
           ++E A  GT V  + A D D G  G   I Y+L  +  +   F +D  SG+I        
Sbjct: 480 VLETAPPGTPVITITAKDRDSGRFGTAGIAYQLLGQGAQH--FSVDRKSGIITVAPCANP 537

Query: 641 -TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699
            T+  LD E    + L   A D     Q+++V + I + D NDSPP F  D     I E 
Sbjct: 538 GTSPCLDYEEQTEYFLTYKATDDDGQGQTTSVSLRISLSDANDSPPRFLQDKYRAVIDEG 597

Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759
           +       +++A D D+   + + Y+I GGD+ + F+++   G    +    VDL   S 
Sbjct: 598 AEKFEPDLKVQARDKDK--TSKITYAIVGGDELDLFAIDQDTGEITIKNKGPVDLT-NST 654

Query: 760 RKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPA 818
                LVI+A+     +   V I + DVN+NAPV    ++   +  +  P+G     V A
Sbjct: 655 HDWIALVIQASDGIFVDSAIVNITIRDVNNNAPVF-PHELYTASLPEISPIGTVVEEVTA 713

Query: 819 YDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            DAD  +  +L YRI  G   +   +NETTG +T+  +L+ +      +EV   D
Sbjct: 714 TDADTGINAELVYRIQKGAFDD-FTINETTGIVTVFRKLDYDNKNTYHVEVIAFD 767



 Score =  144 bits (348), Expect = 4e-32
 Identities = 149/517 (28%), Positives = 235/517 (45%), Gaps = 51/517 (9%)

Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434
           L+E    GT V  L   D  E + + Y I        F +  + G  +IT+A+PLD ++ 
Sbjct: 36  LSESTKVGTEVFVLKGHDP-EGSPVKYGI---QLTDHFVVNPRTG--VITLAKPLDREEN 89

Query: 435 R--RYVLTVSATDSGGRSDTAM---VQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
              R+ +T+      G+    +     + + D N+  P F N PY A   ED P+G+T+L
Sbjct: 90  GTIRFRVTLEDEVPAGQQPNIVGVDAYVIVLDDNDNPPRFLNVPYEAVAEEDLPVGSTIL 149

Query: 490 V-VSATDSD-VGINAQITYSLSSEISN--EAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
             +   D D +G    +T     +  +  E     D +   N  TGA+   + LD     
Sbjct: 150 SGIKVIDPDLLGDTIDLTCVPQPQFLDACEKFGIVDVEKRQNSYTGALVLRQPLDYRERP 209

Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
            Y L + A DG     ++TT VEI V D+ ++ P F   L T  + ED  +GT V  V A
Sbjct: 210 FYQLLLRASDG---LNNETTGVEIKVADIQNSPPEFLDSL-TGVVREDDPIGTLVMTVKA 265

Query: 606 TDADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRES------VATHDLKA 657
            D D G+  ++ YEL  +P D     F++D  +G +RT K L+RE+      V T  ++A
Sbjct: 266 RDGDRGMPRKMIYELVTNPFD----YFLLDDETGELRTAKPLNREALKDSTGVLTLKVRA 321

Query: 658 VAIDGGTPPQS----STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG--EIRA 711
             +  G P       ST    + I+D+ND PP F        I EN P GT +   ++  
Sbjct: 322 RELIDGMPGNDNLTVSTAEATVTIKDVNDEPPTFNRREYNIEIPENVPNGTPLPHLDMTV 381

Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQ--GSDKAEL-VTMVDLDYESP-RKKYELVI 767
            DPD G N+V    ++   D  +F++E     GS    + V    LDYE+P ++K+ +++
Sbjct: 382 KDPDVGLNSVFSLRLEDITD-GAFTIEPTMATGSTSVNIRVANGSLDYENPNQRKFIILV 440

Query: 768 RA----ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV 823
            A      P L +   V + +TD NDN+P   +        +   P  P   + A D D 
Sbjct: 441 VAEEVHTDPKLSSTATVTVSITDANDNSPTFSNPTYTAVVLETAPPGTPVITITAKDRDS 500

Query: 824 ----TDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
               T  + Y++L G  A    ++  +G +T++P  N
Sbjct: 501 GRFGTAGIAYQLL-GQGAQHFSVDRKSGIITVAPCAN 536



 Score = 43.2 bits (97), Expect = 0.11
 Identities = 20/56 (35%), Positives = 31/56 (55%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
            ++  I +LD ND+SP+FE   Y A V   A+    V  + A+D D+G N  + Y +
Sbjct: 1451 VNVTIIILDENDNSPIFERNDYYAGVNSMANVNDFVTKVTASDLDVGDNGTLHYYV 1506


>UniRef50_Q96QU1 Cluster: Protocadherin-15 precursor; n=69;
           Euteleostomi|Rep: Protocadherin-15 precursor - Homo
           sapiens (Human)
          Length = 1955

 Score =  272 bits (667), Expect = 9e-71
 Identities = 254/836 (30%), Positives = 386/836 (46%), Gaps = 96/836 (11%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-----LKATDQDIGKNAEVEYTIEL 64
           +I V D ND+SP F+ + Y A+V E    GTT+ T       ATD D G N ++EY I+ 
Sbjct: 134 RIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQY 193

Query: 65  VTADTLNPEDAXXXXXXXXXXVQDVFRIDGR-SGALLTRASLDREKVARYTVLVKATDQA 123
                 NP+D             D F I    +G ++ R  L+ E   RY V+++A D+A
Sbjct: 194 ------NPDDPTS---------NDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRA 238

Query: 124 SPVSDRLSSTATIHVNIIDDNDNYPQF------------SEKTYTVSVDEDISVTD-NPV 170
             +++R ++T T+ V+++D +D  P F               TY  ++ E  +  + NP+
Sbjct: 239 QNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPI 298

Query: 171 IA--KIKATDAD-----VGANSAIRYAIIGGNTQ---MQFSIDSLSGDVSLVKTLDYEQV 220
           I    I+A D D           I Y+I+ G  +     F +   + ++SL++ ++ +  
Sbjct: 299 IVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFH 358

Query: 221 RSYRLVIRA-QDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSI--- 276
           + + LVI+A QD G P  +    L I I D N+ +P F    +Q  + E+ P+G +I   
Sbjct: 359 QKFDLVIKAEQDNGHPLPA-FAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDS 417

Query: 277 ------VRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA 330
                 +R+ A D D     +    +   DYT      +T    + ++     +DRE Q 
Sbjct: 418 LNLTSPLRIVALDKDIEDTKDPELHLFLNDYTS--VFTVTQTGITRYLTLLQPVDREEQQ 475

Query: 331 KYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTA 390
            Y   +TA DG     S                  F    Y+V +  D  PG  V+ LTA
Sbjct: 476 TYTFSITAFDG--VQESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTA 533

Query: 391 TDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG- 447
            DADE  +  + YEI  G  +G F I      GLIT+A  ++    R Y LTV A D+  
Sbjct: 534 VDADEGSNGEITYEILVG-AQGDFIINKTT--GLITIAPGVEMIVGRTYALTVQAADNAP 590

Query: 448 ---GRSDTAMVQINITDANNYAPV-FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503
               R+    V I +   NN +P  F    Y+  + E   +G  +L + ATD +      
Sbjct: 591 PAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDS 647

Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD 563
           ITY++ +           + F ++  TG +T  K LDRE+   Y+L +TA DG  P  + 
Sbjct: 648 ITYAIEN-------GDPQRVFNLSETTGILTLGKALDRESTDRYILIITASDGR-PDGTS 699

Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK 623
           T  V I V DVNDN PVF   L     + +      V QV ATD D G+NG++HY L   
Sbjct: 700 TATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSL--- 756

Query: 624 DREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS 683
                 F I  ++G I T   L+RE    ++L  VA DG   P+ ST+ + IK+ DI+D+
Sbjct: 757 GNFNNLFRI-TSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDN 815

Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
            PVF +   T  + EN P GTTI +I A D D G N  V Y I+  +  + F+L    G 
Sbjct: 816 SPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTG- 872

Query: 744 DKAELVTMVDLDYES-PRKKYELVIRAASPPLWNDV-----RVEILVTDVNDNAPV 793
              EL  +  LDYE+ P ++  +     +  ++  +      V ++V D+ND  PV
Sbjct: 873 ---ELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPV 925



 Score =  244 bits (598), Expect = 2e-62
 Identities = 212/733 (28%), Positives = 343/733 (46%), Gaps = 63/733 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V+D ND++P F    Y+  V      G +V+ L A D D G N E+ Y I LV A   
Sbjct: 497  IQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEI-LVGA--- 552

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                            Q  F I+  +G +     ++      Y + V+A D A P ++R 
Sbjct: 553  ----------------QGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPP-AERR 595

Query: 131  SSTATIHVNIID-DNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            +S  T+++ ++  +N + P+F +  Y++ + E + V    V+  ++ATD +     +I Y
Sbjct: 596  NSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRV--GAVLLNLQATDRE---GDSITY 650

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            AI  G+ Q  F++   +G ++L K LD E    Y L+I A DG  P  ++T  + I + D
Sbjct: 651  AIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASDG-RPDGTSTATVNIVVTD 709

Query: 250  VNDNAPRFYTSLFQE-SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            VNDNAP F   L +  SV E     + + +V+A D D G+N ++ Y++      GN +  
Sbjct: 710  VNDNAPVFDPYLPRNLSVVEEEANAF-VGQVKATDPDAGINGQVHYSL------GNFNNL 762

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
              I   +G +YT+ +L+RE +  Y+L+V ATDG   PR +T T              F  
Sbjct: 763  FRITS-NGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTN 821

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
              Y V + E+ P GT ++ + A D D    + Y I     +  F++    G   +++ + 
Sbjct: 822  STYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEVKHFFALHPFTGE--LSLLRS 879

Query: 429  LDFK----QERRYVLTVSATDSGGRSDT--AMVQINITDANNYAPVFENAPYTASVFEDA 482
            LD++    QE      V A D  G      A V + + D N+Y PVF    Y   V  DA
Sbjct: 880  LDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDA 939

Query: 483  PIGTTVLVVSATDSDV-GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
              GT +  V A D+D  G+ A     +   + +    +    F +   +G + T   L+ 
Sbjct: 940  VKGTPITTVYAEDADPPGLPAS---RVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNE 996

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN-IMEDALVGTSV 600
            E  + + L V A D G P +S +  V+I V+   +  P F Q+ Y    + E A  GT V
Sbjct: 997  EPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGEI-PRFTQEEYRPPPVSELATKGTMV 1055

Query: 601  SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES-------VATH 653
              + A      +N  I Y +     EE +F I+  +GVI  N  LD E+       V   
Sbjct: 1056 GVISAA----AINQSIVYSI-VSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQAD 1110

Query: 654  DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713
             L+ V  +   P +S+T  V+I+I+D N+ PPVF+       +SE++ + T++  ++A D
Sbjct: 1111 SLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATD 1170

Query: 714  PDEGPNAVVHYSI 726
             D G  +V+ Y +
Sbjct: 1171 KDTGNYSVMAYRL 1183



 Score =  214 bits (523), Expect = 3e-53
 Identities = 214/796 (26%), Positives = 362/796 (45%), Gaps = 66/796 (8%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKAT-DQASPVSDRLSSTATIHVNIIDDNDNYP 148
            F +  R+  L     ++R+   ++ +++KA  D   P    L + A +H+ I+D+N+  P
Sbjct: 338  FHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHP----LPAFAGLHIEILDENNQSP 393

Query: 149  QFSEKTYTVSVDEDI----SVTDNPVIA---KIKATDADVGANSAIRYAIIGGNTQMQFS 201
             F+  +Y   + E      +++D+  +    +I A D D+         +   +    F+
Sbjct: 394  YFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFT 453

Query: 202  IDS--LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259
            +    ++  ++L++ +D E+ ++Y   I A DG     S    + I + D NDN P F  
Sbjct: 454  VTQTGITRYLTLLQPVDREEQQTYTFSITAFDG--VQESEPVIVNIQVMDANDNTPTFPE 511

Query: 260  SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319
              +   V  ++  G S++++ A DADEG N E+TY     +          I+  +G + 
Sbjct: 512  ISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITY-----EILVGAQGDFIINKTTGLIT 566

Query: 320  TSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXXXXFMPG-QYEVELA 376
             +  ++      Y L V A D   P   R++  T                P   Y +E++
Sbjct: 567  IAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEIS 626

Query: 377  EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436
            E    G  ++ L ATD + D+ + Y I  G+ +  F+++     G++T+ + LD +   R
Sbjct: 627  EAMRVGAVLLNLQATDREGDS-ITYAIENGDPQRVFNLSETT--GILTLGKALDRESTDR 683

Query: 437  YVLTVSATDSGGRSD---TAMVQINITDANNYAPVFE-NAPYTASVFEDAPIGTTVLVVS 492
            Y+L ++A+D  GR D   TA V I +TD N+ APVF+   P   SV E+      V  V 
Sbjct: 684  YILIITASD--GRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEE-EANAFVGQVK 740

Query: 493  ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552
            ATD D GIN Q+ YSL          + +  F I    G+I T   L+RE    Y L V 
Sbjct: 741  ATDPDAGINGQVHYSL---------GNFNNLFRIT-SNGSIYTAVKLNREVRDYYELVVV 790

Query: 553  ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612
            A DG V     T  + I V+D++DN PVF    YT  + E+   GT++ Q+ A D D+G 
Sbjct: 791  ATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGA 850

Query: 613  NGRIHYELDPKDREEGSFVIDPASGVIRTNKAL------DRESVATHDLKAVAIDGGTPP 666
            N  + Y +   + +   F + P +G +   ++L      D+E+  T  ++A  I G  PP
Sbjct: 851  N--VSYRIRSPEVKH-FFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPP 907

Query: 667  QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG--PNAVVHY 724
              +TV V +K  D+ND PPVF        ++ ++  GT I  + A D D    P + V Y
Sbjct: 908  GIATVTVIVK--DMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRY 965

Query: 725  SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVE 781
             +         S+   +  D   ++T V+L+ E P   ++LV+ A     P + +   V+
Sbjct: 966  RVDDVQFPYPASIFEVE-EDSGRVITRVNLN-EEPTTIFKLVVVAFDDGEPVMSSSATVK 1023

Query: 782  ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDKLQYRILSGNNANLI 840
            ILV    +  P     +       +    G   G + A  A +   + Y I+SGN  +  
Sbjct: 1024 ILVLHPGE-IPRFTQEEYRPPPVSELATKGTMVGVISA--AAINQSIVYSIVSGNEEDTF 1080

Query: 841  LLNETTGSMTLSPQLN 856
             +N  TG + ++  L+
Sbjct: 1081 GINNITGVIYVNGPLD 1096



 Score =  206 bits (502), Expect = 9e-51
 Identities = 210/779 (26%), Positives = 340/779 (43%), Gaps = 88/779 (11%)

Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIK----ATDADVGANSAIRYAI 191
           + + + D NDN P F  ++Y  +V+E ++     +         ATD D G N  I Y +
Sbjct: 133 VRIVVRDRNDNSPTFKHESYYATVNE-LTPVGTTIFTGFSGDNGATDIDDGPNGQIEY-V 190

Query: 192 IGGNTQMQFSIDS------LSGDVSLVKTLDYEQVRSYRLVIRAQDGG---SPSRSNTTQ 242
           I  N     S D+      L+G++ L K L+YE    Y ++I+A D     +  R+ TT 
Sbjct: 191 IQYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTT 250

Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYS---------------IVR--VQAYDAD 285
           L +++ D +D  P F   +   +  +  P+ Y                IV   +QA D D
Sbjct: 251 LTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQD 310

Query: 286 EGVNAE-----LTYTM---TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVT 337
             +        + Y++   T +DY     +     PR+  +     ++R+   K+ L++ 
Sbjct: 311 RNIQPPSDRPGILYSILVGTPEDYPRFFHM----HPRTAELSLLEPVNRDFHQKFDLVIK 366

Query: 338 ATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG---------TPVVTL 388
           A      P  A A               F    Y+  + E  P G         T  + +
Sbjct: 367 AEQDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRI 426

Query: 389 TATDAD----EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444
            A D D    +D  LH  +   +    F++T       +T+ QP+D ++++ Y  +++A 
Sbjct: 427 VALDKDIEDTKDPELHLFL--NDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAF 484

Query: 445 DSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504
           D    S+  +V I + DAN+  P F    Y   V+ D   G +V+ ++A D+D G N +I
Sbjct: 485 DGVQESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEI 544

Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS--LS 562
           TY        E +      F+IN  TG IT    ++      Y LTV A D   P+   +
Sbjct: 545 TY--------EILVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRN 596

Query: 563 DTTDVEISVVDVNDNEPV-FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621
               V I V+  N+  P  F Q +Y+  I E   VG  +  + ATD +      I Y ++
Sbjct: 597 SICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIE 653

Query: 622 PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681
             D +   F +   +G++   KALDRES   + L   A D G P  +ST  V+I + D+N
Sbjct: 654 NGDPQR-VFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVN 711

Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741
           D+ PVF+                 +G+++A DPD G N  VHYS+  G+ +N F + T  
Sbjct: 712 DNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRI-TSN 768

Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQ 798
           GS    + T V L+ E  R  YELV+ A   A  P  + + + I V D++DN+PV  +  
Sbjct: 769 GS----IYTAVKLNRE-VRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNST 823

Query: 799 IIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
                 ++  P G    ++ A D D+   + YRI S    +   L+  TG ++L   L+
Sbjct: 824 YTV-LVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEVKHFFALHPFTGELSLLRSLD 881



 Score =  194 bits (474), Expect = 2e-47
 Identities = 205/658 (31%), Positives = 297/658 (45%), Gaps = 81/658 (12%)

Query: 11   INVLDCNDHSPV-FEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            I VL  N+ SP  F    Y   + E    G  +L L+ATD++      + Y IE      
Sbjct: 603  IEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIE------ 653

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             N +             Q VF +   +G L    +LDRE   RY +++ A+D   P    
Sbjct: 654  -NGDP------------QRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDG-- 697

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKT-YTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             +STAT+++ + D NDN P F       +SV E+ +   N  + ++KATD D G N  + 
Sbjct: 698  -TSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEA---NAFVGQVKATDPDAGINGQVH 753

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            Y++  GN    F I S +G +     L+ E    Y LV+ A DG    R +T  L I + 
Sbjct: 754  YSL--GNFNNLFRITS-NGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVL 810

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            D++DN+P F  S +   V EN+P G +I++++A D D G N  ++Y +   +    V   
Sbjct: 811  DIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGAN--VSYRIRSPE----VKHF 864

Query: 309  ITIDPRSGWVYTSGQLDRET----QAKYQLLVTATD--GGDPPRSATATXXXXXXXXXXX 362
              + P +G +     LD E     +A    LV A D  G  PP  AT T           
Sbjct: 865  FALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVT--VIVKDMNDY 922

Query: 363  XXXFMPGQYEVELAEDEPPGTPVVTLTATDADED----NRLHYEITGGN---TRGRFSIT 415
               F    Y+  +A D   GTP+ T+ A DAD      +R+ Y +           F + 
Sbjct: 923  PPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVE 982

Query: 416  SQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAP 473
              +GR +  V   L+ +    + L V A D G    S +A V+I +       P F    
Sbjct: 983  EDSGRVITRV--NLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEE 1039

Query: 474  Y-TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
            Y    V E A  GT V V+SA      IN  I YS+ S   NE     +  F IN  TG 
Sbjct: 1040 YRPPPVSELATKGTMVGVISA----AAINQSIVYSIVS--GNE-----EDTFGINNITGV 1088

Query: 533  ITTNKLLDRETMSGYLLTVTA-------RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585
            I  N  LD ET + Y+L V A        +  VPS S+T  V I + D N++ PVF+++ 
Sbjct: 1089 IYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKF 1148

Query: 586  YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG--SFVIDPASGVIRT 641
            Y   + EDA + TSV +V ATD D G    + Y L     +EG   FV++  +G+I+T
Sbjct: 1149 YIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLIKT 1206



 Score =  160 bits (388), Expect = 6e-37
 Identities = 182/695 (26%), Positives = 296/695 (42%), Gaps = 65/695 (9%)

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR-----VQAYDADEGVNAELTYTM 296
           ++ I +RD NDN+P F    +  +V+E  P+G +I         A D D+G N ++ Y +
Sbjct: 132 EVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVI 191

Query: 297 --TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG---DPPRSATAT 351
                D T N    I +   +G +    +L+ E + +Y +++ A D     +  R+ T T
Sbjct: 192 QYNPDDPTSNDTFEIPL-MLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTT 250

Query: 352 XXXXXXXXXXXXXXFMPG------------QYEVELAEDEPPG--TPVVTLTATDA-DED 396
                         F+P              Y+  + E   P    P++      A D+D
Sbjct: 251 LTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQD 310

Query: 397 NRLH---------YEITGGNTRGRFSITSQNGR-GLITVAQPLDFKQERRYVLTVSATDS 446
             +          Y I  G           + R   +++ +P++    +++ L + A   
Sbjct: 311 RNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQD 370

Query: 447 GGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTV---LVVSATDSDVGIN 501
            G    A   + I I D NN +P F    Y   + E AP+G T+   L +++    V ++
Sbjct: 371 NGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD 430

Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGA---ITTNKLLDRETMSGYLLTVTARDGGV 558
             I  +   E+ +  +  +   F +  QTG    +T  + +DRE    Y  ++TA DG  
Sbjct: 431 KDIEDTKDPEL-HLFLNDYTSVFTVT-QTGITRYLTLLQPVDREEQQTYTFSITAFDG-- 486

Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618
              S+   V I V+D NDN P F +  Y   +  D   G SV Q+ A DAD G NG I Y
Sbjct: 487 VQESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITY 546

Query: 619 ELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678
           E+      +G F+I+  +G+I     ++     T+ L   A D   P +    I  + IE
Sbjct: 547 EI--LVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIE 604

Query: 679 DI---NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735
            +   N SPP F     +  ISE   +G  +  ++A D  EG +  + Y+I+ GD    F
Sbjct: 605 VLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATD-REGDS--ITYAIENGDPQRVF 661

Query: 736 SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--PPLWNDVRVEILVTDVNDNAPV 793
           +L    G     L     LD ES   +Y L+I A+   P   +   V I+VTDVNDNAPV
Sbjct: 662 NLSETTGI----LTLGKALDRES-TDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPV 716

Query: 794 MKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSP 853
              +     +  +       G+V A D D     Q     GN  NL  +  + GS+  + 
Sbjct: 717 FDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSLGNFNNLFRIT-SNGSIYTAV 775

Query: 854 QLNTNVPKLATMEVSVTDG-VNEIKAMMQLSVRLI 887
           +LN  V     + V  TDG V+   + + L+++++
Sbjct: 776 KLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVL 810



 Score = 49.2 bits (112), Expect = 0.002
 Identities = 57/216 (26%), Positives = 93/216 (43%), Gaps = 19/216 (8%)

Query: 619 ELDPKDREEGSFVIDPASGVI---RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH- 674
           EL  KD  +   ++DP   ++    T + LDR+         V +      +  T+I H 
Sbjct: 74  ELSLKDNVDYWVLMDPVKQMLFLNSTGRVLDRDPPMNIHSIVVQVQC-INKKVGTIIYHE 132

Query: 675 --IKIEDINDSPPVFESDCLTFYISENSPIGTTI-----GEIRAHDPDEGPNAVVHYSIK 727
             I + D ND+ P F+ +     ++E +P+GTTI     G+  A D D+GPN  + Y I+
Sbjct: 133 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 192

Query: 728 -GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS-PPLWNDVR--VEIL 783
              DD  S             +V    L+YE  + +Y ++I+A       N+ R     L
Sbjct: 193 YNPDDPTSNDTFEIPLMLTGNIVLRKRLNYED-KTRYFVIIQANDRAQNLNERRTTTTTL 251

Query: 784 VTDVNDNAPVMKDFQ--IIFNNYKDCFPVGPFGRVP 817
             DV D   +   F   ++  N +DC P+     +P
Sbjct: 252 TVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIP 287


>UniRef50_UPI0000F2053F Cluster: PREDICTED: similar to FAT tumor
            suppressor homolog 1 (Drosophila),; n=3; Danio rerio|Rep:
            PREDICTED: similar to FAT tumor suppressor homolog 1
            (Drosophila), - Danio rerio
          Length = 1402

 Score =  268 bits (658), Expect = 1e-69
 Identities = 241/782 (30%), Positives = 374/782 (47%), Gaps = 98/782 (12%)

Query: 104  SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI 163
            +++ E+ + YTVL+  +D  +         A++ V ++D NDN P+F +   TVS+ E+ 
Sbjct: 479  TVETEEKSSYTVLLSISDGTN------RDEASVLVEVLDVNDNSPEFEDHPPTVSISENH 532

Query: 164  SVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY 223
             V ++  +A +KATDAD G N+ ++Y ++GG  +  F+ID  +G ++L   LD E    Y
Sbjct: 533  IVGED--VASVKATDADAGFNAEVQYTLLGGAGR--FNIDQETGVITLAAPLDREAQDEY 588

Query: 224  RLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYD 283
             LVI  QD G PS S TT L I + D+NDN+P F    ++ ++ E+  +G  +V V A D
Sbjct: 589  HLVITVQDQGRPSLSTTTDLGITVTDINDNSPIFSKQQYETTMFEDADVGADVVVVMATD 648

Query: 284  ADEGVNAELTYTMTDKDYTGNVDLPI-TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG 342
             D+GVNA +++ + ++  +   D P+  ID  SG V  +G+LD     +Y L V   DGG
Sbjct: 649  KDDGVNAVVSFHIVNQQPSS--DTPVFNIDSDSGSVTLAGKLDYSKAKRYTLDVEGRDGG 706

Query: 343  DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYE 402
             P  + +A                      VE   D+PP         +  + D  ++  
Sbjct: 707  SPSLTGSAVVIVW-----------------VEDVNDKPP-------VFSKDEYDVSIYEN 742

Query: 403  ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDA 462
            + GG       +T ++   ++ V QP+D                 G   TA V I + D 
Sbjct: 743  LAGGTALVSLEVTDEDK--VVAVDQPVD-----------------GLRSTAQVIITVLDI 783

Query: 463  NNYAPVFENAPYTASVFEDAPIGTT---VLVVSATDSDVGINAQITYSLSSEISNEAVAH 519
            N+  P F   P    + E     ++   V  +SATD+D+G N  +T+S SS         
Sbjct: 784  NDNNPQFLPLPELIEIQEGKYTQSSPGEVCKISATDADIGDNGLVTFSTSSY-------- 835

Query: 520  HDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP 579
               +F      G +     LDRE    Y + +TA D G+P L++ T V +S+ DVNDN P
Sbjct: 836  --SKFFSCSDDGTLQAISELDREMQDVYDVVITAVDHGIPQLNNMTTVRVSITDVNDNAP 893

Query: 580  VFKQQLYTANIM-EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV-IDPASG 637
            VF  + Y+ +I+  DA VG  +  V ATD D G N  I Y       E  S V +D  +G
Sbjct: 894  VFSSETYSRSILVRDAKVGELLLTVSATDRDAGDNALITYSFS----EVSSMVALDAETG 949

Query: 638  VIRTNKALDRESVAT-HDLKAVAIDGGTPPQS--STVIVHIKIEDINDSPPVFESDCLTF 694
             I     L   +  T   L A+A D GTP  S  + V++H KI  +++S   FES    F
Sbjct: 950  DITLTSDLSEVTEDTLLTLSAIATDHGTPALSDEAEVLIHFKIASLSESVS-FESSSYNF 1008

Query: 695  YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDL 754
             I EN P  T +G ++A      P   V+Y++K  +D   FS++  +G+ +A L ++   
Sbjct: 1009 MIKENEPEETIVGTVKA--LTGSPLVTVNYNMKSHED--VFSVDA-EGTIQA-LKSLDKE 1062

Query: 755  DYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP---VMKDFQIIFNNYKDCFPVG 811
            D E      E  I + +PP   +  V + V +VN+ AP     K    IFN     FP+ 
Sbjct: 1063 DVEWYILTVE-AIDSRTPPNTAETTVSVQVENVNE-APEFDAEKYTAEIFNIAPYKFPI- 1119

Query: 812  PFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSV 869
               +V A D DV  + KLQY ++      ++ +  +TG + +    ++ V  L T EV  
Sbjct: 1120 --VKVQATDPDVDESSKLQYSLV--KPTTVLDVEASTGQLYVL-DASSIVDPLVTYEVKA 1174

Query: 870  TD 871
            TD
Sbjct: 1175 TD 1176



 Score =  192 bits (467), Expect = 2e-46
 Identities = 187/685 (27%), Positives = 316/685 (46%), Gaps = 75/685 (10%)

Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266
           G++ L+K L+Y  ++ Y   ++AQD G    S+TT + I I D ++  P F  SL++ ++
Sbjct: 77  GNIRLLKHLNYNNIQQYTFTVKAQDTG--GLSDTTAVTITIVDYDNLNPYFDHSLYKATI 134

Query: 267 SENVPIGYSIV---RVQAYDADEGVNAELTYTMT---DKDYTGNVDLPITIDPRSGWVYT 320
            EN    +S V    ++A D D G+N  + Y++T     +Y  N +    I+P SG +  
Sbjct: 135 EENEIGHFSDVTPEAIKAQDGDTGINEPVVYSLTTVLPNEYQSNFE----INPNSGVISV 190

Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380
           +  LDRE   +  L + A    DP ++A A               F   +Y + + E+ P
Sbjct: 191 TTALDREEIDQITLYIQAAQQNDPSKTANAVVSVIIEDVDDNSPKFDQEEYIISIPENSP 250

Query: 381 PGTPVVTLTATDADEDNRL-HYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL 439
               V+    TD D    +    I   +    FSI + +GR L+   + LD +    +  
Sbjct: 251 KDQFVLQTIVTDLDLGGFVGTLRIIPDSV--PFSI-NPDGRILVKRPEDLDRETTAIFSF 307

Query: 440 TVSATDS--GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497
            V A ++      +TA V I + D N+ +P F ++ Y   V+ D  +G  V+ V ATD D
Sbjct: 308 QVEAQENPPSTNKETADVTIILLDENDNSPQFTDSEYEGKVYADQTVGMEVVKVEATDLD 367

Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL--LDRETMSGYLLTVTARD 555
            G NA+I+Y +  E  NE        F +N + GAIT  +L  L    +  + L +TARD
Sbjct: 368 EGPNAEISYFI--EFGNE-----KGFFGLNEKDGAITLVQLIPLVENEILEFALYITARD 420

Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615
           GG  ++S +T   + +    D+ P F Q+ Y   + E+             DA++    +
Sbjct: 421 GG--AISRSTPALVHIQAPGDSHPQFLQKTYQGQVEEN-----------QEDAEI---VK 464

Query: 616 IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675
           +++             IDP   V  T +  ++ S        ++I  GT    ++V+V  
Sbjct: 465 VNF-----------LSIDPFVPVTLTVETEEKSSYTV----LLSISDGTNRDEASVLV-- 507

Query: 676 KIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735
           ++ D+ND+ P FE    T  ISEN  +G  +  ++A D D G NA V Y++ GG  +  F
Sbjct: 508 EVLDVNDNSPEFEDHPPTVSISENHIVGEDVASVKATDADAGFNAEVQYTLLGG--AGRF 565

Query: 736 SLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792
           +++   G     +     LD E+ + +Y LVI       P L     + I VTD+NDN+P
Sbjct: 566 NIDQETG----VITLAAPLDREA-QDEYHLVITVQDQGRPSLSTTTDLGITVTDINDNSP 620

Query: 793 VMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILS---GNNANLILLNETTG 847
           +    Q     ++D         V A D D  V   + + I++    ++  +  ++  +G
Sbjct: 621 IFSKQQYETTMFEDADVGADVVVVMATDKDDGVNAVVSFHIVNQQPSSDTPVFNIDSDSG 680

Query: 848 SMTLSPQLNTNVPKLATMEVSVTDG 872
           S+TL+ +L+ +  K  T++V   DG
Sbjct: 681 SVTLAGKLDYSKAKRYTLDVEGRDG 705



 Score =  177 bits (431), Expect = 4e-42
 Identities = 103/296 (34%), Positives = 152/296 (51%), Gaps = 12/296 (4%)

Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
           + V   ++ +++  Y + +S +D   R D A V + + D N+ +P FE+ P T S+ E+ 
Sbjct: 474 VPVTLTVETEEKSSYTVLLSISDGTNR-DEASVLVEVLDVNDNSPEFEDHPPTVSISENH 532

Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
            +G  V  V ATD+D G NA++ Y+L              +F I+ +TG IT    LDRE
Sbjct: 533 IVGEDVASVKATDADAGFNAEVQYTLLGGAG---------RFNIDQETGVITLAAPLDRE 583

Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
               Y L +T +D G PSLS TTD+ I+V D+NDN P+F +Q Y   + EDA VG  V  
Sbjct: 584 AQDEYHLVITVQDQGRPSLSTTTDLGITVTDINDNSPIFSKQQYETTMFEDADVGADVVV 643

Query: 603 VGATDADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
           V ATD D G+N  + + +       +   F ID  SG +     LD      + L     
Sbjct: 644 VMATDKDDGVNAVVSFHIVNQQPSSDTPVFNIDSDSGSVTLAGKLDYSKAKRYTLDVEGR 703

Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
           DGG+P  + + +V + +ED+ND PPVF  D     I EN   GT +  +   D D+
Sbjct: 704 DGGSPSLTGSAVVIVWVEDVNDKPPVFSKDEYDVSIYENLAGGTALVSLEVTDEDK 759



 Score =  144 bits (349), Expect = 3e-32
 Identities = 95/281 (33%), Positives = 142/281 (50%), Gaps = 29/281 (10%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + VLD ND+SP FE      S+ E    G  V ++KATD D G NAEV+YT+ L  A   
Sbjct: 507 VEVLDVNDNSPEFEDHPPTVSISENHIVGEDVASVKATDADAGFNAEVQYTL-LGGAGRF 565

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           N                    ID  +G +   A LDRE    Y +++   DQ  P    L
Sbjct: 566 N--------------------IDQETGVITLAAPLDREAQDEYHLVITVQDQGRP---SL 602

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           S+T  + + + D NDN P FS++ Y  ++ ED  V  + V+  + ATD D G N+ + + 
Sbjct: 603 STTTDLGITVTDINDNSPIFSKQQYETTMFEDADVGADVVV--VMATDKDDGVNAVVSFH 660

Query: 191 IIGGNTQMQ---FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
           I+          F+IDS SG V+L   LDY + + Y L +  +DGGSPS + +  +++ +
Sbjct: 661 IVNQQPSSDTPVFNIDSDSGSVTLAGKLDYSKAKRYTLDVEGRDGGSPSLTGSAVVIVWV 720

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV 288
            DVND  P F    +  S+ EN+  G ++V ++  D D+ V
Sbjct: 721 EDVNDKPPVFSKDEYDVSIYENLAGGTALVSLEVTDEDKVV 761



 Score =  126 bits (304), Expect = 9e-27
 Identities = 112/422 (26%), Positives = 174/422 (41%), Gaps = 21/422 (4%)

Query: 66  TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125
           T  T+ P DA            DV R DG    L     L+   + +YT  VKA D    
Sbjct: 50  TVRTIKPLDADEIKQPPAPEDFDV-RSDGNIRLL---KHLNYNNIQQYTFTVKAQDTGG- 104

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE-DISVTDNPVIAKIKATDADVGAN 184
               LS T  + + I+D ++  P F    Y  +++E +I    +     IKA D D G N
Sbjct: 105 ----LSDTTAVTITIVDYDNLNPYFDHSLYKATIEENEIGHFSDVTPEAIKAQDGDTGIN 160

Query: 185 SAIRYA---IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
             + Y+   ++    Q  F I+  SG +S+   LD E++    L I+A     PS++   
Sbjct: 161 EPVVYSLTTVLPNEYQSNFEINPNSGVISVTTALDREEIDQITLYIQAAQQNDPSKTANA 220

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
            + + I DV+DN+P+F    +  S+ EN P    +++    D D G      +  T +  
Sbjct: 221 VVSVIIEDVDDNSPKFDQEEYIISIPENSPKDQFVLQTIVTDLDLG-----GFVGTLRII 275

Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
             +V   I  D R   V     LDRET A +   V A +        TA           
Sbjct: 276 PDSVPFSINPDGRI-LVKRPEDLDRETTAIFSFQVEAQENPPSTNKETADVTIILLDEND 334

Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNG 419
               F   +YE ++  D+  G  VV + ATD DE  +  + Y I  GN +G F +  ++G
Sbjct: 335 NSPQFTDSEYEGKVYADQTVGMEVVKVEATDLDEGPNAEISYFIEFGNEKGFFGLNEKDG 394

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479
              +    PL   +   + L ++A D G  S +    ++I    +  P F    Y   V 
Sbjct: 395 AITLVQLIPLVENEILEFALYITARDGGAISRSTPALVHIQAPGDSHPQFLQKTYQGQVE 454

Query: 480 ED 481
           E+
Sbjct: 455 EN 456



 Score =  113 bits (271), Expect = 9e-23
 Identities = 108/378 (28%), Positives = 163/378 (43%), Gaps = 20/378 (5%)

Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
           P+    L +  TD D+    +    L ++   +  A  D  F +    G I   K L+  
Sbjct: 32  PVALDFLELVYTDGDLNATVRTIKPLDADEIKQPPAPED--FDVRSD-GNIRLLKHLNYN 88

Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL---VGTS 599
            +  Y  TV A+D G   LSDTT V I++VD ++  P F   LY A I E+ +      +
Sbjct: 89  NIQQYTFTVKAQDTG--GLSDTTAVTITIVDYDNLNPYFDHSLYKATIEENEIGHFSDVT 146

Query: 600 VSQVGATDADVGLNGRIHYELDP--KDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
              + A D D G+N  + Y L     +  + +F I+P SGVI    ALDRE +    L  
Sbjct: 147 PEAIKAQDGDTGINEPVVYSLTTVLPNEYQSNFEINPNSGVISVTTALDREEIDQITLYI 206

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
            A     P +++  +V + IED++D+ P F+ +     I ENSP    + +    D D G
Sbjct: 207 QAAQQNDPSKTANAVVSVIIEDVDDNSPKFDQEEYIISIPENSPKDQFVLQTIVTDLDLG 266

Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN- 776
                  +++   DS  FS+       +  +    DLD E+       V    +PP  N 
Sbjct: 267 GFV---GTLRIIPDSVPFSINP---DGRILVKRPEDLDRETTAIFSFQVEAQENPPSTNK 320

Query: 777 -DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILS 833
               V I++ D NDN+P   D +     Y D        +V A D D     ++ Y I  
Sbjct: 321 ETADVTIILLDENDNSPQFTDSEYEGKVYADQTVGMEVVKVEATDLDEGPNAEISYFIEF 380

Query: 834 GNNANLILLNETTGSMTL 851
           GN      LNE  G++TL
Sbjct: 381 GNEKGFFGLNEKDGAITL 398



 Score =  110 bits (265), Expect = 5e-22
 Identities = 101/346 (29%), Positives = 163/346 (47%), Gaps = 34/346 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVRE---GASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
           I ++D ++ +P F+   Y+A++ E   G  S  T   +KA D D G N  V Y++     
Sbjct: 113 ITIVDYDNLNPYFDHSLYKATIEENEIGHFSDVTPEAIKAQDGDTGINEPVVYSLT---- 168

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
            T+ P +            Q  F I+  SG +    +LDRE++ + T+ ++A  Q  P  
Sbjct: 169 -TVLPNE-----------YQSNFEINPNSGVISVTTALDREEIDQITLYIQAAQQNDPSK 216

Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
              ++ A + V I D +DN P+F ++ Y +S+ E+ S  D  V+  I  TD D+G     
Sbjct: 217 ---TANAVVSVIIEDVDDNSPKFDQEEYIISIPEN-SPKDQFVLQTI-VTDLDLGGFVGT 271

Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
              I      + FSI+   G + LVK    LD E    +   + AQ+    +   T  + 
Sbjct: 272 LRII---PDSVPFSINP-DGRI-LVKRPEDLDRETTAIFSFQVEAQENPPSTNKETADVT 326

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           I + D NDN+P+F  S ++  V  +  +G  +V+V+A D DEG NAE++Y +   +  G 
Sbjct: 327 IILLDENDNSPQFTDSEYEGKVYADQTVGMEVVKVEATDLDEGPNAEISYFIEFGNEKGF 386

Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350
             L    D     V     ++ E   ++ L +TA DGG   RS  A
Sbjct: 387 FGLN-EKDGAITLVQLIPLVENEI-LEFALYITARDGGAISRSTPA 430



 Score =  106 bits (255), Expect = 8e-21
 Identities = 125/473 (26%), Positives = 195/473 (41%), Gaps = 54/473 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGA---SSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
            I VLD ND++P F        ++EG    SS   V  + ATD DIG N        LVT 
Sbjct: 778  ITVLDINDNNPQFLPLPELIEIQEGKYTQSSPGEVCKISATDADIGDNG-------LVTF 830

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
             T +                  F      G L   + LDRE    Y V++ A D   P  
Sbjct: 831  STSS---------------YSKFFSCSDDGTLQAISELDREMQDVYDVVITAVDHGIP-- 873

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSV-DEDISVTDNPVIAKIKATDADVGANSA 186
             +L++  T+ V+I D NDN P FS +TY+ S+   D  V +  ++  + ATD D G N+ 
Sbjct: 874  -QLNNMTTVRVSITDVNDNAPVFSSETYSRSILVRDAKVGE--LLLTVSATDRDAGDNAL 930

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTL-DYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
            I Y+          ++D+ +GD++L   L +  +     L   A D G+P+ S+  ++LI
Sbjct: 931  ITYSF--SEVSSMVALDAETGDITLTSDLSEVTEDTLLTLSAIATDHGTPALSDEAEVLI 988

Query: 246  NIRDVN-DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
            + +  +   +  F +S +   + EN P    +  V+A      V   + Y M   +   +
Sbjct: 989  HFKIASLSESVSFESSSYNFMIKENEPEETIVGTVKALTGSPLVT--VNYNMKSHEDVFS 1046

Query: 305  VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
            VD         G +     LD+E    Y L V A D   PP +A  T             
Sbjct: 1047 VDA-------EGTIQALKSLDKEDVEWYILTVEAIDSRTPPNTA-ETTVSVQVENVNEAP 1098

Query: 365  XFMPGQYEVELAEDEPPGTPVVTLTAT--DADEDNRLHYEITGGNTRGRFSITSQNGRGL 422
             F   +Y  E+    P   P+V + AT  D DE ++L Y +    T     + +  G+  
Sbjct: 1099 EFDAEKYTAEIFNIAPYKFPIVKVQATDPDVDESSKLQYSLVKPTT--VLDVEASTGQLY 1156

Query: 423  ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINI--TDANNYAPVFENAP 473
            +  A  +    +      V ATD  G   T  V+I +  + ++N   +  N P
Sbjct: 1157 VLDASSI---VDPLVTYEVKATDKHGLFTTTAVEITVKQSASDNIVVISLNQP 1206



 Score = 98.3 bits (234), Expect = 3e-18
 Identities = 119/449 (26%), Positives = 176/449 (39%), Gaps = 36/449 (8%)

Query: 267 SENVPIGYSIVRVQAYDADEGVNAEL-TYTMTDKDYTGNVDLPITIDPRS-GWVYTSGQL 324
           S   P+    + +   D D  +NA + T    D D       P   D RS G +     L
Sbjct: 28  SHRFPVALDFLELVYTDGD--LNATVRTIKPLDADEIKQPPAPEDFDVRSDGNIRLLKHL 85

Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
           +     +Y   V A D G    S T                F    Y+  + E+E     
Sbjct: 86  NYNNIQQYTFTVKAQDTGG--LSDTTAVTITIVDYDNLNPYFDHSLYKATIEENEIGHFS 143

Query: 385 VVTLTATDA-DEDNRLH----YEITG---GNTRGRFSITSQNGRGLITVAQPLDFKQERR 436
            VT  A  A D D  ++    Y +T       +  F I   +G  +I+V   LD ++  +
Sbjct: 144 DVTPEAIKAQDGDTGINEPVVYSLTTVLPNEYQSNFEINPNSG--VISVTTALDREEIDQ 201

Query: 437 YVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494
             L + A      S TA  +V + I D ++ +P F+   Y  S+ E++P    VL    T
Sbjct: 202 ITLYIQAAQQNDPSKTANAVVSVIIEDVDDNSPKFDQEEYIISIPENSPKDQFVLQTIVT 261

Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL--LDRETMSGYLLTVT 552
           D D+G            +    +      F INP  G I   +   LDRET + +   V 
Sbjct: 262 DLDLG----------GFVGTLRIIPDSVPFSINPD-GRILVKRPEDLDRETTAIFSFQVE 310

Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612
           A++    +  +T DV I ++D NDN P F    Y   +  D  VG  V +V ATD D G 
Sbjct: 311 AQENPPSTNKETADVTIILLDENDNSPQFTDSEYEGKVYADQTVGMEVVKVEATDLDEGP 370

Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNK--ALDRESVATHDLKAVAIDGGTPPQSST 670
           N  I Y ++    E+G F ++   G I   +   L    +    L   A DGG   +S+ 
Sbjct: 371 NAEISYFIE-FGNEKGFFGLNEKDGAITLVQLIPLVENEILEFALYITARDGGAISRSTP 429

Query: 671 VIVHIKIEDINDSPPVFESDCLTFYISEN 699
            +VHI+     DS P F        + EN
Sbjct: 430 ALVHIQAP--GDSHPQFLQKTYQGQVEEN 456



 Score = 79.8 bits (188), Expect = 1e-12
 Identities = 72/289 (24%), Positives = 132/289 (45%), Gaps = 33/289 (11%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVR-EGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68
            ++++ D ND++PVF  + Y  S+    A  G  +LT+ ATD+D G NA + Y+   V+  
Sbjct: 882  RVSITDVNDNAPVFSSETYSRSILVRDAKVGELLLTVSATDRDAGDNALITYSFSEVS-- 939

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP-VS 127
            ++   DA          + +V         LLT +++             ATD  +P +S
Sbjct: 940  SMVALDAETGDITLTSDLSEV-----TEDTLLTLSAI-------------ATDHGTPALS 981

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
            D   +   IH  I   +++   F   +Y   + E  +  +  ++  +KA          +
Sbjct: 982  D--EAEVLIHFKIASLSESV-SFESSSYNFMIKE--NEPEETIVGTVKALTG--SPLVTV 1034

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
             Y +   + +  FS+D+  G +  +K+LD E V  Y L + A D  +P  +  T + + +
Sbjct: 1035 NYNM--KSHEDVFSVDA-EGTIQALKSLDKEDVEWYILTVEAIDSRTPPNTAETTVSVQV 1091

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
             +VN+ AP F    +   +    P  + IV+VQA D D   +++L Y++
Sbjct: 1092 ENVNE-APEFDAEKYTAEIFNIAPYKFPIVKVQATDPDVDESSKLQYSL 1139


>UniRef50_UPI00006A1F6A Cluster: UPI00006A1F6A related cluster; n=3;
           Xenopus tropicalis|Rep: UPI00006A1F6A UniRef100 entry -
           Xenopus tropicalis
          Length = 644

 Score =  260 bits (638), Expect = 3e-67
 Identities = 190/601 (31%), Positives = 286/601 (47%), Gaps = 46/601 (7%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           +F I+  +G++ T +++DRE       L+        +S + +    + + ++D NDN P
Sbjct: 66  LFSINSTTGSIYTTSNIDRES------LISDVINLVVLSSQPTYPTEVRITVLDINDNSP 119

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI------ 202
            F E    V + ED+       I  + A+D D G N+ +RY+I+ GN    FSI      
Sbjct: 120 VFQEPHSKVEISEDLP--PGSYICGVSASDGDTGLNANLRYSIVSGNKLGWFSISENSGL 177

Query: 203 -DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261
            D LSG +S    LD EQ     L I A D G+P  S+T ++++++ DVNDN+P FY   
Sbjct: 178 LDPLSGKLSNRADLDREQQDRCTLQILATDLGTPPLSSTAKVIVSLLDVNDNSPVFYPVQ 237

Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321
           +  ++ EN P    +  V A D D G+N  + Y++   D +        + P +G + T 
Sbjct: 238 YFANIQENEPPASFVATVTASDPDLGINGTIRYSIRAGDTS-----KFQVHPETGAISTK 292

Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE-VELAEDEP 380
             LDRE +  YQL V ATDGG       A               F  G Y    ++E   
Sbjct: 293 AALDREEKTAYQLQVVATDGGGLQSHNHAIVTITVLDTQDNPPSFSQGSYSFASISELAS 352

Query: 381 PGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYV 438
             T V+ ++++D DE N   + Y I  GN    F++ S  G+  + +   LD++    Y 
Sbjct: 353 NMTQVLRVSSSDVDEGNNGLISYSIMKGNEEKHFTMDSSTGQ--VALVGRLDYEATASYS 410

Query: 439 LTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496
           L + A DSG    S T+ + I + D N+ +P F  A     V E+  +G  V  V+ATDS
Sbjct: 411 LIIQAVDSGAVPLSATSTLSIEVLDENDNSPSFPKAALFVDVVENMRVGELVSSVTATDS 470

Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556
           D G NA I YS++         ++   F I+P TG+I   K LD ET + Y L +TA+D 
Sbjct: 471 DSGDNADIHYSITG-------TNNHGTFSISPNTGSIFLAKKLDFETQALYKLNITAKDK 523

Query: 557 GVPSLSDTTDVEISVVDVNDNEPVF-------KQQLYTANIMEDALVGTSVSQVGATDAD 609
           G P  S T  V I V D NDN P F        Q  + A+      +G+ +S + A D D
Sbjct: 524 GNPPRSSTMSVIIKVRDFNDNPPSFPAVPTFVSQNAFAAD--PSLAIGSVLSTITAFDPD 581

Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669
            G NG I YE+   D E  +F++D  SG +R    +   S   + L   A D G   +++
Sbjct: 582 EGSNGEIEYEIISGDTE--TFIVDRYSGDLRVAAPM-LPSHLIYSLIVAATDLGAERKAT 638

Query: 670 T 670
           T
Sbjct: 639 T 639



 Score =  241 bits (591), Expect = 1e-61
 Identities = 186/592 (31%), Positives = 289/592 (48%), Gaps = 45/592 (7%)

Query: 310 TIDPRSGWVYTSGQLDRETQAKYQL-LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
           +I+  +G +YT+  +DRE+     + LV  +     P     T              F  
Sbjct: 68  SINSTTGSIYTTSNIDRESLISDVINLVVLSSQPTYPTEVRITVLDINDNSPV----FQE 123

Query: 369 GQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNG-----RG 421
              +VE++ED PPG+ +  ++A+D D   +  L Y I  GN  G FSI+  +G      G
Sbjct: 124 PHSKVEISEDLPPGSYICGVSASDGDTGLNANLRYSIVSGNKLGWFSISENSGLLDPLSG 183

Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVF 479
            ++    LD +Q+ R  L + ATD G    S TA V +++ D N+ +PVF    Y A++ 
Sbjct: 184 KLSNRADLDREQQDRCTLQILATDLGTPPLSSTAKVIVSLLDVNDNSPVFYPVQYFANIQ 243

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           E+ P  + V  V+A+D D+GIN  I YS+         A    +F ++P+TGAI+T   L
Sbjct: 244 ENEPPASFVATVTASDPDLGINGTIRYSIR--------AGDTSKFQVHPETGAISTKAAL 295

Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT-ANIMEDALVGT 598
           DRE  + Y L V A DGG     +   V I+V+D  DN P F Q  Y+ A+I E A   T
Sbjct: 296 DREEKTAYQLQVVATDGGGLQSHNHAIVTITVLDTQDNPPSFSQGSYSFASISELASNMT 355

Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
            V +V ++D D G NG I Y +  K  EE  F +D ++G +     LD E+ A++ L   
Sbjct: 356 QVLRVSSSDVDEGNNGLISYSI-MKGNEEKHFTMDSSTGQVALVGRLDYEATASYSLIIQ 414

Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
           A+D G  P S+T  + I++ D ND+ P F    L   + EN  +G  +  + A D D G 
Sbjct: 415 AVDSGAVPLSATSTLSIEVLDENDNSPSFPKAALFVDVVENMRVGELVSSVTATDSDSGD 474

Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLW 775
           NA +HYSI G ++  +FS+    GS    +     LD+E+ +  Y+L I A    +PP  
Sbjct: 475 NADIHYSITGTNNHGTFSISPNTGS----IFLAKKLDFET-QALYKLNITAKDKGNPPRS 529

Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-------FGRVPAYDAD--VTDK 826
           + + V I V D NDN P         +  ++ F   P          + A+D D     +
Sbjct: 530 STMSVIIKVRDFNDNPPSFPAVPTFVS--QNAFAADPSLAIGSVLSTITAFDPDEGSNGE 587

Query: 827 LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKA 878
           ++Y I+SG+    I+   +      +P L +++  + ++ V+ TD   E KA
Sbjct: 588 IEYEIISGDTETFIVDRYSGDLRVAAPMLPSHL--IYSLIVAATDLGAERKA 637



 Score =  241 bits (591), Expect = 1e-61
 Identities = 182/571 (31%), Positives = 277/571 (48%), Gaps = 45/571 (7%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +I VLD ND+SPVF+    +  + E    G+ +  + A+D D G NA + Y+I  V+ + 
Sbjct: 108 RITVLDINDNSPVFQEPHSKVEISEDLPPGSYICGVSASDGDTGLNANLRYSI--VSGNK 165

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
           L                ++   +D  SG L  RA LDRE+  R T+ + ATD  +P    
Sbjct: 166 LG----------WFSISENSGLLDPLSGKLSNRADLDREQQDRCTLQILATDLGTP---P 212

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           LSSTA + V+++D NDN P F    Y  ++ E+        +A + A+D D+G N  IRY
Sbjct: 213 LSSTAKVIVSLLDVNDNSPVFYPVQYFANIQENEPPAS--FVATVTASDPDLGINGTIRY 270

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
           +I  G+T  +F +   +G +S    LD E+  +Y+L + A DGG     N   + I + D
Sbjct: 271 SIRAGDTS-KFQVHPETGAISTKAALDREEKTAYQLQVVATDGGGLQSHNHAIVTITVLD 329

Query: 250 VNDNAPRFYTSLFQ-ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
             DN P F    +   S+SE       ++RV + D DEG N  ++Y++      GN +  
Sbjct: 330 TQDNPPSFSQGSYSFASISELASNMTQVLRVSSSDVDEGNNGLISYSI----MKGNEEKH 385

Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
            T+D  +G V   G+LD E  A Y L++ A D G  P SAT+T              F  
Sbjct: 386 FTMDSSTGQVALVGRLDYEATASYSLIIQAVDSGAVPLSATSTLSIEVLDENDNSPSFPK 445

Query: 369 GQYEVELAEDEPPGTPVVTLTATDADE-DNR-LHYEITGGNTRGRFSITSQNGRGLITVA 426
               V++ E+   G  V ++TATD+D  DN  +HY ITG N  G FSI+   G   I +A
Sbjct: 446 AALFVDVVENMRVGELVSSVTATDSDSGDNADIHYSITGTNNHGTFSISPNTGS--IFLA 503

Query: 427 QPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAP--YTASVFEDA 482
           + LDF+ +  Y L ++A D G   RS T  V I + D N+  P F   P   + + F   
Sbjct: 504 KKLDFETQALYKLNITAKDKGNPPRSSTMSVIIKVRDFNDNPPSFPAVPTFVSQNAFAAD 563

Query: 483 P---IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKL 538
           P   IG+ +  ++A D D G N +I Y        E ++   + F+++  +G +     +
Sbjct: 564 PSLAIGSVLSTITAFDPDEGSNGEIEY--------EIISGDTETFIVDRYSGDLRVAAPM 615

Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569
           L    +  Y L V A D G    + TT++ I
Sbjct: 616 LPSHLI--YSLIVAATDLGAERKATTTELTI 644



 Score =  214 bits (522), Expect = 3e-53
 Identities = 156/508 (30%), Positives = 243/508 (47%), Gaps = 25/508 (4%)

Query: 374 ELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ 433
           ++ E++PPGT V T++           + +        FSI S  G   I     +D + 
Sbjct: 36  QVLEEQPPGTYVGTISTKPGFTYRLSEFHVL-------FSINSTTGS--IYTTSNIDRES 86

Query: 434 ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
               V+ +    S     T  V+I + D N+ +PVF+       + ED P G+ +  VSA
Sbjct: 87  LISDVINLVVLSSQPTYPTE-VRITVLDINDNSPVFQEPHSKVEISEDLPPGSYICGVSA 145

Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553
           +D D G+NA + YS+ S       +  +   +++P +G ++    LDRE      L + A
Sbjct: 146 SDGDTGLNANLRYSIVSGNKLGWFSISENSGLLDPLSGKLSNRADLDREQQDRCTLQILA 205

Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613
            D G P LS T  V +S++DVNDN PVF    Y ANI E+    + V+ V A+D D+G+N
Sbjct: 206 TDLGTPPLSSTAKVIVSLLDVNDNSPVFYPVQYFANIQENEPPASFVATVTASDPDLGIN 265

Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673
           G I Y +   D  +  F + P +G I T  ALDRE    + L+ VA DGG     +  IV
Sbjct: 266 GTIRYSIRAGDTSK--FQVHPETGAISTKAALDREEKTAYQLQVVATDGGGLQSHNHAIV 323

Query: 674 HIKIEDINDSPPVFESDCLTF-YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732
            I + D  D+PP F     +F  ISE +   T +  + + D DEG N ++ YSI  G++ 
Sbjct: 324 TITVLDTQDNPPSFSQGSYSFASISELASNMTQVLRVSSSDVDEGNNGLISYSIMKGNEE 383

Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVND 789
             F++++  G    ++  +  LDYE+    Y L+I+A    + PL     + I V D ND
Sbjct: 384 KHFTMDSSTG----QVALVGRLDYEA-TASYSLIIQAVDSGAVPLSATSTLSIEVLDEND 438

Query: 790 NAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDK--LQYRILSGNNANLILLNETT 846
           N+P       +F +  +   VG     V A D+D  D   + Y I   NN     ++  T
Sbjct: 439 NSPSFPK-AALFVDVVENMRVGELVSSVTATDSDSGDNADIHYSITGTNNHGTFSISPNT 497

Query: 847 GSMTLSPQLNTNVPKLATMEVSVTDGVN 874
           GS+ L+ +L+     L  + ++  D  N
Sbjct: 498 GSIFLAKKLDFETQALYKLNITAKDKGN 525


>UniRef50_A6VVW9 Cluster: Autotransporter-associated beta strand
            repeat protein; n=2; cellular organisms|Rep:
            Autotransporter-associated beta strand repeat protein -
            Marinomonas sp. MWYL1
          Length = 3391

 Score =  260 bits (637), Expect = 4e-67
 Identities = 265/903 (29%), Positives = 395/903 (43%), Gaps = 96/903 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTADT 69
            ++V D ND++PV        SV E A + T + T  ATD D    N+ + Y+        
Sbjct: 2034 VSVNDLNDNTPVMTSGA-TGSVDENADTSTVIYTATATDADGTAANSTLVYS-------- 2084

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV--S 127
            L+ +DA            D   ID  +G +  +AS D E    Y+  V ATD  +    S
Sbjct: 2085 LSGDDA------------DKLIIDATTGEVTLKASADYETQTSYSFNVVATDNGAGNFNS 2132

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSA 186
              LS+T  + V++ D NDN P  +    T SV+E+   +   VI    ATDAD   ANS 
Sbjct: 2133 GSLSTTQAVIVSVNDLNDNTPVMTSGA-TGSVNENADTST--VIYTATATDADGTAANST 2189

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG-----SPSRSNTT 241
            + Y++ G +   +  ID+ +G+V+L  + DYE   SY   + A D G     S S S T 
Sbjct: 2190 LVYSLSGDDAD-KLIIDATTGEVTLKASADYETQTSYSFNVVATDNGAGNFNSGSLSTTQ 2248

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKD 300
             +++++ D+NDN P   TS    SV+EN      I    A DAD    N  L Y+++  D
Sbjct: 2249 AVIVSVNDLNDNTP-VMTSGATGSVNENADTSTVIYTATATDADGTATNNTLRYSLSGDD 2307

Query: 301  YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG----DPPRSATATXXXXX 356
                    + I+  +G V      D ET++ Y   V ATD G    +    +T       
Sbjct: 2308 AA-----LLDINAVTGVVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVIVS 2362

Query: 357  XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFS 413
                      M       + E+    T + T T TDAD    +N L Y ++G +   +  
Sbjct: 2363 VNDLNDNTPVMTSGATGSVDENADTSTVIYTATGTDADGTAANNTLRYSLSGDDA-DKLI 2421

Query: 414  ITSQNGRGLITVAQPLDFKQERRYVLTVSATD-------SGGRSDTAMVQINITDANNYA 466
            I +  G   +T+    D++ +  Y   V ATD       SG  S T  V +++ D N+  
Sbjct: 2422 IDATTGE--VTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNT 2479

Query: 467  PVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFV 525
            PV  ++  T SV E+A   T +   +ATD+D    N  + YSLS +  + A+        
Sbjct: 2480 PVMTSSA-TGSVNENADTSTVIYTATATDADGTATNNTLRYSLSGD--DAALLD------ 2530

Query: 526  INPQTGAITTNKLLDRETMSGYLLTVTARDGGVP-----SLSDTTDVEISVVDVNDNEPV 580
            IN  TG +T     D ET S Y   V A D G       SLS T  V +SV D+NDN PV
Sbjct: 2531 INAVTGVVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNAPV 2590

Query: 581  FKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVI 639
                  TA+I E+A   T V    ATDAD    N  I + L   D    +F +D ++GV+
Sbjct: 2591 ITSGA-TASIDENAATSTVVYTATATDADGTSANNTISFSLTGTDA--AAFDVDSSTGVV 2647

Query: 640  RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699
                + D E+ +++    +A D G    + T  V + + D+ND+ PV  S   T  I EN
Sbjct: 2648 TLKASADYETKSSYSFNVIATDNGAGNLTDTQAVIVSVNDLNDNAPVITSGA-TASIDEN 2706

Query: 700  SPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM-VDLDYE 757
            +   T +    A D D    N  + +S+ G  D+ +F +++  G     +VT+    DYE
Sbjct: 2707 AATSTVVYTATATDADGTSANNAISFSLTG-TDAAAFDIDSSTG-----VVTLKASADYE 2760

Query: 758  SPRKKYELVIRAA--------SPPLWNDVRVEILVTDVNDNAPVMKDFQI-IFNNYKDCF 808
            + +  Y   + A         S  L     V + V D+NDN PVM        N   D  
Sbjct: 2761 T-KASYSFNVVATDNGAGNFNSGSLSTTQAVIVSVNDLNDNTPVMTSGATGSVNENADTS 2819

Query: 809  PVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVS 868
             V         D    +      LSG++A+ ++++ TTG +TL    +       +  V 
Sbjct: 2820 TVIYTATATDADGTAANSTLVYSLSGDDADKLIIDATTGEVTLKASADYETQTSYSFNVV 2879

Query: 869  VTD 871
             TD
Sbjct: 2880 ATD 2882



 Score =  259 bits (635), Expect = 7e-67
 Identities = 250/823 (30%), Positives = 369/823 (44%), Gaps = 91/823 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTADT 69
            ++V D ND++PV        SV E A + T + T  ATD D    N+ + Y+        
Sbjct: 2143 VSVNDLNDNTPVMTSGA-TGSVNENADTSTVIYTATATDADGTAANSTLVYS-------- 2193

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV--S 127
            L+ +DA            D   ID  +G +  +AS D E    Y+  V ATD  +    S
Sbjct: 2194 LSGDDA------------DKLIIDATTGEVTLKASADYETQTSYSFNVVATDNGAGNFNS 2241

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSA 186
              LS+T  + V++ D NDN P  +    T SV+E+   +   VI    ATDAD    N+ 
Sbjct: 2242 GSLSTTQAVIVSVNDLNDNTPVMTSGA-TGSVNENADTST--VIYTATATDADGTATNNT 2298

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG-----SPSRSNTT 241
            +RY++ G +  +   I++++G V+L  + DYE   SY   + A D G     S S S T 
Sbjct: 2299 LRYSLSGDDAAL-LDINAVTGVVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQ 2357

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKD 300
             +++++ D+NDN P   TS    SV EN      I      DAD    N  L Y+++  D
Sbjct: 2358 AVIVSVNDLNDNTP-VMTSGATGSVDENADTSTVIYTATGTDADGTAANNTLRYSLSGDD 2416

Query: 301  YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG----DPPRSATATXXXXX 356
                    + ID  +G V      D ET++ Y   V ATD G    +    +T       
Sbjct: 2417 AD-----KLIIDATTGEVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVS 2471

Query: 357  XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFS 413
                      M       + E+    T + T TATDAD    +N L Y ++G +      
Sbjct: 2472 VNDLNDNTPVMTSSATGSVNENADTSTVIYTATATDADGTATNNTLRYSLSGDDA-ALLD 2530

Query: 414  ITSQNGRGLITVAQPLDFKQERRYVLTVSATD-------SGGRSDTAMVQINITDANNYA 466
            I +  G  ++T+    D++ +  Y   V ATD       SG  S T  V +++ D N+ A
Sbjct: 2531 INAVTG--VVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNA 2588

Query: 467  PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
            PV  +   TAS+ E+A   T V   +ATD+D G +A  T S S   ++ A       F +
Sbjct: 2589 PVITSGA-TASIDENAATSTVVYTATATDAD-GTSANNTISFSLTGTDAAA------FDV 2640

Query: 527  NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586
            +  TG +T     D ET S Y   V A D G  +L+DT  V +SV D+NDN PV      
Sbjct: 2641 DSSTGVVTLKASADYETKSSYSFNVIATDNGAGNLTDTQAVIVSVNDLNDNAPVITSGA- 2699

Query: 587  TANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645
            TA+I E+A   T V    ATDAD    N  I + L   D    +F ID ++GV+    + 
Sbjct: 2700 TASIDENAATSTVVYTATATDADGTSANNAISFSLTGTD--AAAFDIDSSTGVVTLKASA 2757

Query: 646  DRESVATHDLKAVAIDGG-----TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700
            D E+ A++    VA D G     +   S+T  V + + D+ND+ PV  S   T  ++EN+
Sbjct: 2758 DYETKASYSFNVVATDNGAGNFNSGSLSTTQAVIVSVNDLNDNTPVMTSGA-TGSVNENA 2816

Query: 701  PIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759
               T I    A D D    N+ + YS+  GDD++   ++   G    E+      DYE+ 
Sbjct: 2817 DTSTVIYTATATDADGTAANSTLVYSL-SGDDADKLIIDATTG----EVTLKASADYET- 2870

Query: 760  RKKYELVIRAA--------SPPLWNDVRVEILVTDVNDNAPVM 794
            +  Y   + A         S  L     V + V D+NDN P +
Sbjct: 2871 QTSYSFNVVATDNGAGNFNSGSLSTTQAVIVSVNDLNDNTPTV 2913



 Score =  250 bits (611), Expect = 6e-64
 Identities = 260/904 (28%), Positives = 391/904 (43%), Gaps = 98/904 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTADT 69
            ++V D ND++PV        SV E A + T + T   TD D    N  + Y+        
Sbjct: 1925 VSVNDLNDNTPVMTSGA-TGSVDENADTSTVIYTATGTDADGTATNNTLRYS-------- 1975

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV--S 127
            L+ +DA            D   ID  +G +  +AS D E    Y+  V ATD  +    S
Sbjct: 1976 LSGDDA------------DKLIIDATTGEVTLKASADYETQTSYSFNVVATDNGAGNFNS 2023

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSA 186
              LS+T  + V++ D NDN P  +    T SVDE+   +   VI    ATDAD   ANS 
Sbjct: 2024 GSLSTTQAVIVSVNDLNDNTPVMTSGA-TGSVDENADTST--VIYTATATDADGTAANST 2080

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG-----SPSRSNTT 241
            + Y++ G +   +  ID+ +G+V+L  + DYE   SY   + A D G     S S S T 
Sbjct: 2081 LVYSLSGDDAD-KLIIDATTGEVTLKASADYETQTSYSFNVVATDNGAGNFNSGSLSTTQ 2139

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKD 300
             +++++ D+NDN P   TS    SV+EN      I    A DAD    N+ L Y+++  D
Sbjct: 2140 AVIVSVNDLNDNTP-VMTSGATGSVNENADTSTVIYTATATDADGTAANSTLVYSLSGDD 2198

Query: 301  YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG----DPPRSATATXXXXX 356
                    + ID  +G V      D ETQ  Y   V ATD G    +    +T       
Sbjct: 2199 AD-----KLIIDATTGEVTLKASADYETQTSYSFNVVATDNGAGNFNSGSLSTTQAVIVS 2253

Query: 357  XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFS 413
                      M       + E+    T + T TATDAD    +N L Y ++G +      
Sbjct: 2254 VNDLNDNTPVMTSGATGSVNENADTSTVIYTATATDADGTATNNTLRYSLSGDDA-ALLD 2312

Query: 414  ITSQNGRGLITVAQPLDFKQERRYVLTVSATD-------SGGRSDTAMVQINITDANNYA 466
            I +    G++T+    D++ +  Y   V ATD       SG  S T  V +++ D N+  
Sbjct: 2313 INAVT--GVVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVIVSVNDLNDNT 2370

Query: 467  PVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFV 525
            PV  +   T SV E+A   T +   + TD+D    N  + YSLS + ++        + +
Sbjct: 2371 PVMTSGA-TGSVDENADTSTVIYTATGTDADGTAANNTLRYSLSGDDAD--------KLI 2421

Query: 526  INPQTGAITTNKLLDRETMSGYLLTVTARDGGV-----PSLSDTTDVEISVVDVNDNEPV 580
            I+  TG +T     D ET S Y   V A D G       SLS T  V +SV D+NDN PV
Sbjct: 2422 IDATTGEVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNTPV 2481

Query: 581  FKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVI 639
                  T ++ E+A   T +    ATDAD    N  + Y L   D       I+  +GV+
Sbjct: 2482 MTSSA-TGSVNENADTSTVIYTATATDADGTATNNTLRYSLSGDD--AALLDINAVTGVV 2538

Query: 640  RTNKALDRESVATHDLKAVAIDGG-----TPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694
                + D E+ +++    +A D G     +   S+T  V + + D+ND+ PV  S   T 
Sbjct: 2539 TLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNAPVITSGA-TA 2597

Query: 695  YISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM-V 752
             I EN+   T +    A D D    N  + +S+  G D+ +F +++  G     +VT+  
Sbjct: 2598 SIDENAATSTVVYTATATDADGTSANNTISFSLT-GTDAAAFDVDSSTG-----VVTLKA 2651

Query: 753  DLDYESPRKKYELVIRAASPPLWN--DVRVEIL-VTDVNDNAPVMKD--FQIIFNNYKDC 807
              DYE+ +  Y   + A      N  D +  I+ V D+NDNAPV+       I  N    
Sbjct: 2652 SADYET-KSSYSFNVIATDNGAGNLTDTQAVIVSVNDLNDNAPVITSGATASIDENAATS 2710

Query: 808  FPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867
              V       A      + + +  L+G +A    ++ +TG +TL    +       +  V
Sbjct: 2711 TVVYTATATDADGTSANNAISFS-LTGTDAAAFDIDSSTGVVTLKASADYETKASYSFNV 2769

Query: 868  SVTD 871
              TD
Sbjct: 2770 VATD 2773



 Score =  241 bits (589), Expect = 3e-61
 Identities = 258/909 (28%), Positives = 387/909 (42%), Gaps = 103/909 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTADT 69
            ++V D ND++PV        SV E A + T + T  ATD D    N  + Y++    A  
Sbjct: 1816 VSVNDLNDNTPVMTSGA-TGSVNENADTSTVIYTATATDADGTATNNTLRYSLSGADAAL 1874

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV--S 127
            L+                    I+  +G +  +AS D E  + Y+  V ATD  +    S
Sbjct: 1875 LD--------------------INAVTGVVTLKASADYETKSSYSFNVIATDNGAGNLNS 1914

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSA 186
              LS+T  + V++ D NDN P  +    T SVDE+   +   VI     TDAD    N+ 
Sbjct: 1915 GSLSTTQAVTVSVNDLNDNTPVMTSGA-TGSVDENADTST--VIYTATGTDADGTATNNT 1971

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG-----SPSRSNTT 241
            +RY++ G +   +  ID+ +G+V+L  + DYE   SY   + A D G     S S S T 
Sbjct: 1972 LRYSLSGDDAD-KLIIDATTGEVTLKASADYETQTSYSFNVVATDNGAGNFNSGSLSTTQ 2030

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKD 300
             +++++ D+NDN P   TS    SV EN      I    A DAD    N+ L Y+++  D
Sbjct: 2031 AVIVSVNDLNDNTP-VMTSGATGSVDENADTSTVIYTATATDADGTAANSTLVYSLSGDD 2089

Query: 301  YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG----DPPRSATATXXXXX 356
                    + ID  +G V      D ETQ  Y   V ATD G    +    +T       
Sbjct: 2090 AD-----KLIIDATTGEVTLKASADYETQTSYSFNVVATDNGAGNFNSGSLSTTQAVIVS 2144

Query: 357  XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFS 413
                      M       + E+    T + T TATDAD    ++ L Y ++G +   +  
Sbjct: 2145 VNDLNDNTPVMTSGATGSVNENADTSTVIYTATATDADGTAANSTLVYSLSGDDA-DKLI 2203

Query: 414  ITSQNGRGLITVAQPLDFKQERRYVLTVSATD-------SGGRSDTAMVQINITDANNYA 466
            I +  G   +T+    D++ +  Y   V ATD       SG  S T  V +++ D N+  
Sbjct: 2204 IDATTGE--VTLKASADYETQTSYSFNVVATDNGAGNFNSGSLSTTQAVIVSVNDLNDNT 2261

Query: 467  PVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFV 525
            PV  +   T SV E+A   T +   +ATD+D    N  + YSLS +  + A+        
Sbjct: 2262 PVMTSGA-TGSVNENADTSTVIYTATATDADGTATNNTLRYSLSGD--DAALLD------ 2312

Query: 526  INPQTGAITTNKLLDRETMSGYLLTVTARDGGV-----PSLSDTTDVEISVVDVNDNEPV 580
            IN  TG +T     D ET S Y   V A D G       SLS T  V +SV D+NDN PV
Sbjct: 2313 INAVTGVVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVIVSVNDLNDNTPV 2372

Query: 581  FKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVI 639
                  T ++ E+A   T +     TDAD    N  + Y L   D ++   +ID  +G +
Sbjct: 2373 MTSGA-TGSVDENADTSTVIYTATGTDADGTAANNTLRYSLSGDDADK--LIIDATTGEV 2429

Query: 640  RTNKALDRESVATHDLKAVAIDGG-----TPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694
                + D E+ +++    +A D G     +   S+T  V + + D+ND+ PV  S   T 
Sbjct: 2430 TLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNTPVMTSSA-TG 2488

Query: 695  YISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM-V 752
             ++EN+   T I    A D D    N  + YS+  GDD+    +    G     +VT+  
Sbjct: 2489 SVNENADTSTVIYTATATDADGTATNNTLRYSL-SGDDAALLDINAVTG-----VVTLKA 2542

Query: 753  DLDYESPRKKYELVIRAA--------SPPLWNDVRVEILVTDVNDNAPVMKD--FQIIFN 802
              DYE+ +  Y   + A         S  L     V + V D+NDNAPV+       I  
Sbjct: 2543 SADYET-KSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNAPVITSGATASIDE 2601

Query: 803  NYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKL 862
            N      V       A      + + +  L+G +A    ++ +TG +TL    +      
Sbjct: 2602 NAATSTVVYTATATDADGTSANNTISFS-LTGTDAAAFDVDSSTGVVTLKASADYETKSS 2660

Query: 863  ATMEVSVTD 871
             +  V  TD
Sbjct: 2661 YSFNVIATD 2669



 Score =  235 bits (575), Expect = 1e-59
 Identities = 241/873 (27%), Positives = 371/873 (42%), Gaps = 82/873 (9%)

Query: 42   VLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLT 101
            V+T  AT  ++ +NA     I   TA   + +            +     I+  +GA+  
Sbjct: 1509 VITSGATG-NVDENASTSTVIYTATATDADNDSLTYSLSGTDAAL---LNINASTGAVTL 1564

Query: 102  RASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE 161
            + S D E    Y+  +  TD +   S  L+ +  + V++ D ND+ P  +    T SV+E
Sbjct: 1565 KNSADYETKNTYSFNIVVTDSS---SGHLTGSKAVTVSVNDLNDHTPVMTSGA-TGSVNE 1620

Query: 162  DISVTDNPVIAKIKATDAD-VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV 220
            +     + VI    ATDAD    N+ +RY++ G +  +   I+ ++G V+L  + DYE  
Sbjct: 1621 NADT--STVIYTATATDADGTATNNTLRYSLSGADAAL-LDINVVTGVVTLKASADYETK 1677

Query: 221  RSYRLVIRAQDGG-----SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275
             SY   + A D G     S S S T  + +++ D+NDN P   TS    SV+EN      
Sbjct: 1678 SSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNTPAM-TSGATGSVNENADTSTV 1736

Query: 276  IVRVQAYDAD-EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQL 334
            I    A DAD    N  L Y+++  D        + I+  +G V      D ET++ Y  
Sbjct: 1737 IYTATATDADGTATNNTLRYSLSGADAA-----LLDINAVTGVVTLKASADYETKSSYSF 1791

Query: 335  LVTATDGG----DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTA 390
             V ATD G    +    +T                 M       + E+    T + T TA
Sbjct: 1792 NVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNTPVMTSGATGSVNENADTSTVIYTATA 1851

Query: 391  TDAD---EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD-- 445
            TDAD    +N L Y ++G +      I +    G++T+    D++ +  Y   V ATD  
Sbjct: 1852 TDADGTATNNTLRYSLSGADA-ALLDINAVT--GVVTLKASADYETKSSYSFNVIATDNG 1908

Query: 446  -----SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VG 499
                 SG  S T  V +++ D N+  PV  +   T SV E+A   T +   + TD+D   
Sbjct: 1909 AGNLNSGSLSTTQAVTVSVNDLNDNTPVMTSGA-TGSVDENADTSTVIYTATGTDADGTA 1967

Query: 500  INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV- 558
             N  + YSLS + ++        + +I+  TG +T     D ET + Y   V A D G  
Sbjct: 1968 TNNTLRYSLSGDDAD--------KLIIDATTGEVTLKASADYETQTSYSFNVVATDNGAG 2019

Query: 559  ----PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD-VGLN 613
                 SLS T  V +SV D+NDN PV      T ++ E+A   T +    ATDAD    N
Sbjct: 2020 NFNSGSLSTTQAVIVSVNDLNDNTPVMTSGA-TGSVDENADTSTVIYTATATDADGTAAN 2078

Query: 614  GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG-----TPPQS 668
              + Y L   D ++   +ID  +G +    + D E+  ++    VA D G     +   S
Sbjct: 2079 STLVYSLSGDDADK--LIIDATTGEVTLKASADYETQTSYSFNVVATDNGAGNFNSGSLS 2136

Query: 669  STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIK 727
            +T  V + + D+ND+ PV  S   T  ++EN+   T I    A D D    N+ + YS+ 
Sbjct: 2137 TTQAVIVSVNDLNDNTPVMTSGA-TGSVNENADTSTVIYTATATDADGTAANSTLVYSL- 2194

Query: 728  GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA--------SPPLWNDVR 779
             GDD++   ++   G    E+      DYE+ +  Y   + A         S  L     
Sbjct: 2195 SGDDADKLIIDATTG----EVTLKASADYET-QTSYSFNVVATDNGAGNFNSGSLSTTQA 2249

Query: 780  VEILVTDVNDNAPVMKDFQI-IFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNAN 838
            V + V D+NDN PVM        N   D   V         D   T+      LSG++A 
Sbjct: 2250 VIVSVNDLNDNTPVMTSGATGSVNENADTSTVIYTATATDADGTATNNTLRYSLSGDDAA 2309

Query: 839  LILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            L+ +N  TG +TL    +       +  V  TD
Sbjct: 2310 LLDINAVTGVVTLKASADYETKSSYSFNVIATD 2342



 Score =  212 bits (517), Expect = 1e-52
 Identities = 215/770 (27%), Positives = 327/770 (42%), Gaps = 71/770 (9%)

Query: 139  NIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQM 198
            N I   DN         T +VDE+ S +   VI    ATDAD   N ++ Y++ G +  +
Sbjct: 1498 NDITLKDNAAPVITSGATGNVDENASTST--VIYTATATDAD---NDSLTYSLSGTDAAL 1552

Query: 199  QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY 258
              +I++ +G V+L  + DYE   +Y   I   D  S   + +  + +++ D+ND+ P   
Sbjct: 1553 -LNINASTGAVTLKNSADYETKNTYSFNIVVTDSSSGHLTGSKAVTVSVNDLNDHTP-VM 1610

Query: 259  TSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317
            TS    SV+EN      I    A DAD    N  L Y+++  D    +D+ +     +G 
Sbjct: 1611 TSGATGSVNENADTSTVIYTATATDADGTATNNTLRYSLSGAD-AALLDINVV----TGV 1665

Query: 318  VYTSGQLDRETQAKYQLLVTATDGG----DPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373
            V      D ET++ Y   V ATD G    +    +T                 M      
Sbjct: 1666 VTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNTPAMTSGATG 1725

Query: 374  ELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
             + E+    T + T TATDAD    +N L Y ++G +      I +    G++T+    D
Sbjct: 1726 SVNENADTSTVIYTATATDADGTATNNTLRYSLSGADA-ALLDINAVT--GVVTLKASAD 1782

Query: 431  FKQERRYVLTVSATD-------SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
            ++ +  Y   V ATD       SG  S T  V +++ D N+  PV  +   T SV E+A 
Sbjct: 1783 YETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNTPVMTSGA-TGSVNENAD 1841

Query: 484  IGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
              T +   +ATD+D    N  + YSLS   ++ A+        IN  TG +T     D E
Sbjct: 1842 TSTVIYTATATDADGTATNNTLRYSLSG--ADAALLD------INAVTGVVTLKASADYE 1893

Query: 543  TMSGYLLTVTARDGGV-----PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
            T S Y   V A D G       SLS T  V +SV D+NDN PV      T ++ E+A   
Sbjct: 1894 TKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNTPVMTSGA-TGSVDENADTS 1952

Query: 598  TSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
            T +     TDAD    N  + Y L   D ++   +ID  +G +    + D E+  ++   
Sbjct: 1953 TVIYTATGTDADGTATNNTLRYSLSGDDADK--LIIDATTGEVTLKASADYETQTSYSFN 2010

Query: 657  AVAIDGG-----TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711
             VA D G     +   S+T  V + + D+ND+ PV  S   T  + EN+   T I    A
Sbjct: 2011 VVATDNGAGNFNSGSLSTTQAVIVSVNDLNDNTPVMTSGA-TGSVDENADTSTVIYTATA 2069

Query: 712  HDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770
             D D    N+ + YS+  GDD++   ++   G    E+      DYE+ +  Y   + A 
Sbjct: 2070 TDADGTAANSTLVYSL-SGDDADKLIIDATTG----EVTLKASADYET-QTSYSFNVVAT 2123

Query: 771  --------SPPLWNDVRVEILVTDVNDNAPVMKDFQI-IFNNYKDCFPVGPFGRVPAYDA 821
                    S  L     V + V D+NDN PVM        N   D   V         D 
Sbjct: 2124 DNGAGNFNSGSLSTTQAVIVSVNDLNDNTPVMTSGATGSVNENADTSTVIYTATATDADG 2183

Query: 822  DVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
               +      LSG++A+ ++++ TTG +TL    +       +  V  TD
Sbjct: 2184 TAANSTLVYSLSGDDADKLIIDATTGEVTLKASADYETQTSYSFNVVATD 2233



 Score =  202 bits (493), Expect = 1e-49
 Identities = 192/639 (30%), Positives = 285/639 (44%), Gaps = 73/639 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTADT 69
            ++V D ND++PV        SV E A + T + T   TD D    N  + Y+        
Sbjct: 2361 VSVNDLNDNTPVMTSGA-TGSVDENADTSTVIYTATGTDADGTAANNTLRYS-------- 2411

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV--S 127
            L+ +DA            D   ID  +G +  +AS D E  + Y+  V ATD  +    S
Sbjct: 2412 LSGDDA------------DKLIIDATTGEVTLKASADYETKSSYSFNVIATDNGAGNLNS 2459

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSA 186
              LS+T  + V++ D NDN P  +    T SV+E+   +   VI    ATDAD    N+ 
Sbjct: 2460 GSLSTTQAVTVSVNDLNDNTPVMTSSA-TGSVNENADTST--VIYTATATDADGTATNNT 2516

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG-----SPSRSNTT 241
            +RY++ G +  +   I++++G V+L  + DYE   SY   + A D G     S S S T 
Sbjct: 2517 LRYSLSGDDAAL-LDINAVTGVVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQ 2575

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
             + +++ D+NDNAP   TS    S+ EN      +    A DAD G +A  T + +    
Sbjct: 2576 AVTVSVNDLNDNAP-VITSGATASIDENAATSTVVYTATATDAD-GTSANNTISFS---L 2630

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
            TG       +D  +G V      D ET++ Y   V ATD G    + T            
Sbjct: 2631 TGTDAAAFDVDSSTGVVTLKASADYETKSSYSFNVIATDNGAGNLTDTQAVIVSVNDLND 2690

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQN 418
                   G     + E+    T V T TATDAD    +N + + +TG +    F I S  
Sbjct: 2691 NAPVITSGA-TASIDENAATSTVVYTATATDADGTSANNAISFSLTGTDAAA-FDIDSST 2748

Query: 419  GRGLITVAQPLDFKQERRYVLTVSATD-------SGGRSDTAMVQINITDANNYAPVFEN 471
            G  ++T+    D++ +  Y   V ATD       SG  S T  V +++ D N+  PV  +
Sbjct: 2749 G--VVTLKASADYETKASYSFNVVATDNGAGNFNSGSLSTTQAVIVSVNDLNDNTPVMTS 2806

Query: 472  APYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
               T SV E+A   T +   +ATD+D    N+ + YSLS + +++         +I+  T
Sbjct: 2807 GA-TGSVNENADTSTVIYTATATDADGTAANSTLVYSLSGDDADK--------LIIDATT 2857

Query: 531  GAITTNKLLDRETMSGYLLTVTARDGGVP-----SLSDTTDVEISVVDVNDNEPVFKQQL 585
            G +T     D ET + Y   V A D G       SLS T  V +SV D+NDN P      
Sbjct: 2858 GEVTLKASADYETQTSYSFNVVATDNGAGNFNSGSLSTTQAVIVSVNDLNDNTPTVSAGA 2917

Query: 586  YTANIME-----DALVGTSVSQVGATDADVGLNGRIHYE 619
             TA ++E     +A  GT+ S +  T  DV   G + Y+
Sbjct: 2918 ETAILVEAGGVNNAAAGTNSSSITLTKGDVDTVGSVSYD 2956



 Score =  101 bits (242), Expect = 3e-19
 Identities = 97/316 (30%), Positives = 143/316 (45%), Gaps = 42/316 (13%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            ++V D ND++PV       AS+ E A++ T V T  ATD D G +A    +  L   D  
Sbjct: 2683 VSVNDLNDNAPVITSGA-TASIDENAATSTVVYTATATDAD-GTSANNAISFSLTGTDAA 2740

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV--SD 128
                               F ID  +G +  +AS D E  A Y+  V ATD  +    S 
Sbjct: 2741 ------------------AFDIDSSTGVVTLKASADYETKASYSFNVVATDNGAGNFNSG 2782

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSAI 187
             LS+T  + V++ D NDN P  +    T SV+E+   +   VI    ATDAD   ANS +
Sbjct: 2783 SLSTTQAVIVSVNDLNDNTPVMTSGA-TGSVNENADTST--VIYTATATDADGTAANSTL 2839

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG-----SPSRSNTTQ 242
             Y++ G +   +  ID+ +G+V+L  + DYE   SY   + A D G     S S S T  
Sbjct: 2840 VYSLSGDDAD-KLIIDATTGEVTLKASADYETQTSYSFNVVATDNGAGNFNSGSLSTTQA 2898

Query: 243  LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE-LTYTMTDKDY 301
            +++++ D+NDN P         +VS        +      +A  G N+  +T T  D D 
Sbjct: 2899 VIVSVNDLNDNTP---------TVSAGAETAILVEAGGVNNAAAGTNSSSITLTKGDVDT 2949

Query: 302  TGNVDLPITIDPRSGW 317
             G+V    T    +GW
Sbjct: 2950 VGSVSYDATYLTNNGW 2965


>UniRef50_UPI0000D5573F Cluster: PREDICTED: similar to CG3389-PA; n=1;
            Tribolium castaneum|Rep: PREDICTED: similar to CG3389-PA
            - Tribolium castaneum
          Length = 1870

 Score =  260 bits (636), Expect = 5e-67
 Identities = 218/750 (29%), Positives = 341/750 (45%), Gaps = 54/750 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + +LD N+ +PVF  +    ++RE  + G+ +  LKA D D  K A++ YTI     +  
Sbjct: 826  VTILDINNKNPVF-YEPGSVTMRENTAVGSVIAKLKAKDLD--KTAQLVYTINPKFCEAK 882

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N  +             + F +   SG L     LDRE V +  + +   D AS    ++
Sbjct: 883  N--ERGILLKLSDFNCAETFHLHPMSGVLTIAQQLDREMVEKVQMGLMVEDTASETGPQI 940

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S+T TI +NI D NDN P+F +  Y  S+ E+    +   I  + A DAD   N  I Y 
Sbjct: 941  STT-TITINIEDINDNSPKFRQPYYKFSITENSK--NGVTIGNVLAEDAD--KNKTITYT 995

Query: 191  IIGGN--TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            + G    T++ + +DS SGD+ +   +D+E      L I+A D G P+R +  ++ I I 
Sbjct: 996  LDGRFEITELIY-LDSNSGDLVVANKIDHEIYDWLNLTIKATDSGIPARFSRVEIFIQIL 1054

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            D NDN P F        +SE+ P+G  +  ++A DAD G   ++TY +      G     
Sbjct: 1055 DENDNNPFFLGEPQSLLISEDTPVGRQVAIIEAKDADSGEFGKITYLLDRISSEGK---- 1110

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG------GDPPRSATATXXXXXXXXXXX 362
             +ID  SG +  S +LDRE +  Y L++ A D           R+A              
Sbjct: 1111 FSIDADSGILKVSDKLDREEKHSYLLVIEAWDNYQYGFNSGESRNAFKHINVTILDVNDN 1170

Query: 363  XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN----RLHYEITGGNTRGRFSITSQN 418
                    Y V + E   PG  + T  A+DAD+ N    ++  +I+ GN +  F++ SQ 
Sbjct: 1171 HPQLHVPPYCVNITEFHEPGQAITTFHASDADDPNTSNGQVIIDISDGNQKNFFAL-SQI 1229

Query: 419  GRGLITVAQPLDFK-QERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPY- 474
                  +      + +   Y L + A D G  S      + I +TD N++ P F   P+ 
Sbjct: 1230 SEWSAELRTTTSLRGRHGNYTLIIRAQDLGTPSHLIEEPLHICVTDFNDHPPTFVTPPHN 1289

Query: 475  -TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
             T  V E+A IG+ ++ + ATD DVG N  + Y L ++      A H + F + P +G +
Sbjct: 1290 STLRVPENATIGSALVKIIATDEDVGSNGIVRYRLKAD-----PAGHWKSFNLQPVSGIL 1344

Query: 534  TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593
                 LDR+    Y + + A D GVPSLS   D+ + V ++ND +P F    +T N  E+
Sbjct: 1345 ELRLPLDRKKQKVYDIRIEAYDLGVPSLSSDLDLTVYVSNINDYQPQFMGDEFTVNFTEN 1404

Query: 594  ALVGTSVSQVGAT-DADV----GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648
                    ++  T D D     G    I Y +     E G F + P   ++  ++ LDRE
Sbjct: 1405 KPSEVERQKLPQTVDRDELEFDGPFAPICYFI-VGGNENGLFKLHPVEHILTVSRPLDRE 1463

Query: 649  SVATHDLKAVAIDGGT-PPQSSTVI---------VHIKIEDINDSPPVFESDCLTFYISE 698
               TH L   A +  T PP++ +           V +K+ D+ND+ P F     T  +S 
Sbjct: 1464 EKDTHLLLVKATEDCTKPPRNESFFDSSDDTQLKVIVKVLDVNDNAPQFIHRVFTGGVST 1523

Query: 699  NSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
             +  GTT  E++A D D   NA + Y + G
Sbjct: 1524 ATSFGTTFMEVKAEDADLDDNARMSYFLIG 1553



 Score =  253 bits (619), Expect = 6e-65
 Identities = 246/869 (28%), Positives = 385/869 (44%), Gaps = 92/869 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTADT 69
            I V D NDH+P+FE   Y  SV E  S GT++L ++A D D    N  + Y I+   +D 
Sbjct: 713  IYVQDVNDHAPLFEYTFYNKSVPEDISGGTSILQVRAKDFDGSSPNNRIVYRIQNGASDK 772

Query: 70   --LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
              + PE                  I    GA L    L + +   Y++ V A D A P  
Sbjct: 773  FIIAPESGI---------------ISVARGASLD-PDLTQPRTLHYSLNVVALDGA-PGE 815

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN--- 184
            ++L +  T++V I+D N+  P F E   +V++ E+ +V    VIAK+KA D D  A    
Sbjct: 816  NQLQAGVTVNVTILDINNKNPVFYEPG-SVTMRENTAV--GSVIAKLKAKDLDKTAQLVY 872

Query: 185  ------------SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232
                          I   +   N    F +  +SG +++ + LD E V   ++ +  +D 
Sbjct: 873  TINPKFCEAKNERGILLKLSDFNCAETFHLHPMSGVLTIAQQLDREMVEKVQMGLMVEDT 932

Query: 233  GSPS--RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290
             S +  + +TT + INI D+NDN+P+F    ++ S++EN   G +I  V A DAD+  N 
Sbjct: 933  ASETGPQISTTTITINIEDINDNSPKFRQPYYKFSITENSKNGVTIGNVLAEDADK--NK 990

Query: 291  ELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350
             +TYT+   D    +   I +D  SG +  + ++D E      L + ATD G P R +  
Sbjct: 991  TITYTL---DGRFEITELIYLDSNSGDLVVANKIDHEIYDWLNLTIKATDSGIPARFSRV 1047

Query: 351  TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNT 408
                           F+     + ++ED P G  V  + A DAD  E  ++ Y +   ++
Sbjct: 1048 EIFIQILDENDNNPFFLGEPQSLLISEDTPVGRQVAIIEAKDADSGEFGKITYLLDRISS 1107

Query: 409  RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS------GGRSDTAMVQINIT-- 460
             G+FSI + +G  ++ V+  LD +++  Y+L + A D+       G S  A   IN+T  
Sbjct: 1108 EGKFSIDADSG--ILKVSDKLDREEKHSYLLVIEAWDNYQYGFNSGESRNAFKHINVTIL 1165

Query: 461  DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG--INAQITYSLSSEISNEAVA 518
            D N+  P     PY  ++ E    G  +    A+D+D     N Q+   +S        A
Sbjct: 1166 DVNDNHPQLHVPPYCVNITEFHEPGQAITTFHASDADDPNTSNGQVIIDISDGNQKNFFA 1225

Query: 519  HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578
                   I+  +  + T   L R     Y L + A+D G PS      + I V D ND+ 
Sbjct: 1226 LSQ----ISEWSAELRTTTSL-RGRHGNYTLIIRAQDLGTPSHLIEEPLHICVTDFNDHP 1280

Query: 579  PVFKQQLY--TANIMEDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDREEGSFVIDP 634
            P F    +  T  + E+A +G+++ ++ ATD DVG NG + Y L  DP    + SF + P
Sbjct: 1281 PTFVTPPHNSTLRVPENATIGSALVKIIATDEDVGSNGIVRYRLKADPAGHWK-SFNLQP 1339

Query: 635  ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694
             SG++     LDR+    +D++  A D G P  SS + + + + +IND  P F  D  T 
Sbjct: 1340 VSGILELRLPLDRKKQKVYDIRIEAYDLGVPSLSSDLDLTVYVSNINDYQPQFMGDEFTV 1399

Query: 695  YISENSPIGTTIGEI-RAHDPDE----GPNAVVHYSIKGGDDSNSFSLE----------- 738
              +EN P      ++ +  D DE    GP A + Y I GG+++  F L            
Sbjct: 1400 NFTENKPSEVERQKLPQTVDRDELEFDGPFAPICYFIVGGNENGLFKLHPVEHILTVSRP 1459

Query: 739  -TRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDF 797
              R+  D   L+     D   P +       +    L    +V + V DVNDNAP     
Sbjct: 1460 LDREEKDTHLLLVKATEDCTKPPRNESFFDSSDDTQL----KVIVKVLDVNDNAPQF-IH 1514

Query: 798  QIIFNNYKDCFPVG-PFGRVPAYDADVTD 825
            ++           G  F  V A DAD+ D
Sbjct: 1515 RVFTGGVSTATSFGTTFMEVKAEDADLDD 1543



 Score =  235 bits (576), Expect = 1e-59
 Identities = 227/793 (28%), Positives = 355/793 (44%), Gaps = 63/793 (7%)

Query: 88  DVFRIDGRSGA---LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDN 144
           DV R++  S     +     LDRE    Y +++  TD      + ++ +  + V   D N
Sbjct: 96  DVIRVENISPTEADVYLNKELDRETRDEYPLVLTLTDGRLGHGNYVTQSLLLLVE--DVN 153

Query: 145 DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ-FSID 203
           DN P F+    ++++ ED +     VIA ++ATD D GA   + Y +   +T+   FS+ 
Sbjct: 154 DNTPIFTSHQSSITLREDAAPG---VIATLEATDLDEGAYGQVVYQLQEVDTKESLFSVS 210

Query: 204 SLSGD--VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT--TQLLINIRDVNDNAPRFYT 259
           +  G   V LV +LDYE+   ++L + A D     R NT    LL+ + DV D  P F  
Sbjct: 211 TAGGKAIVRLVGSLDYEKQTLHQLKVLAVDRAKQGRVNTGTAALLVKVEDVEDQPPEFVR 270

Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319
                 ++EN PIG S+++V A D D GVN  + Y+++        D+  +++  +G + 
Sbjct: 271 VTSVARIAENAPIGTSVLQVTAIDGDRGVNNPILYSLSSNSIDRITDV-FSLEETTGTLL 329

Query: 320 TSGQLDRE----TQAKYQLLVTATDGG---DPPRSATATXXXXXXXXXXXXXXFMPGQYE 372
           T+  LDRE    +   Y L +TAT+ G    PP S T                F  G YE
Sbjct: 330 TAKTLDRESLSLSSGTYILQITATEYGGKIKPPPSVTTEVTVIITDINDETPKFRSGYYE 389

Query: 373 VELAEDEPPGTPVVTLTAT-----DADEDNRLHYEITGGNTRGRFSITS----QNGRGLI 423
            E+AE+ P  TP+  L +      D D+     +++        F IT          +I
Sbjct: 390 CEIAENAPVNTPLTFLGSAMPEVYDHDQGINGTFQLYVKGASDVFEITPTKAINEATFMI 449

Query: 424 TVAQP--LDFKQERRYVLTVSATD---SGGRSDTAMVQINITDANNYAPVFENAPYTASV 478
            V     LD+++ +    T+ A +      + +   V  +I D N+  P F    Y   V
Sbjct: 450 RVKNSTFLDYEKIKTINFTLVAKEIVKHNPKFNEVPVVAHILDRNDNYPEFTKNVYEVFV 509

Query: 479 FEDAPIGTTVLVVSATDSDVGI--NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
            E+  IG TV  V A D D G+     I Y+  S      +  H    +I+ +T      
Sbjct: 510 PENCDIGATVAWVQALDDDSGVFGTMGIRYTHLSGSIQHMLNLHPTTGIISVKTAG---G 566

Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
              DRE +S + LTV ARD        T  + I++ DVNDN P+F Q  Y A ++E+ L 
Sbjct: 567 PNWDREQISRHYLTVEARDDLGQGNRITVQLIINIEDVNDNPPIFTQNRYEARLLENKLD 626

Query: 597 GTSVSQVGATDADVG--LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD-------- 646
             +  +V A DAD+    N  I Y L   D    +F I+P++G+I+   ++D        
Sbjct: 627 FENPLKVEARDADLNGTKNNEIEYSLF-GDLSH-NFTIEPSTGIIKPRTSIDFEALEGSL 684

Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706
           ++S+    L   A D GTP   S V ++I ++D+ND  P+FE       + E+   GT+I
Sbjct: 685 KDSIRQLHLTVRARDWGTPSLFSDVPLYIYVQDVNDHAPLFEYTFYNKSVPEDISGGTSI 744

Query: 707 GEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYE 764
            ++RA D D   PN  + Y I+ G  S+ F +    G         +D D   PR   Y 
Sbjct: 745 LQVRAKDFDGSSPNNRIVYRIQNG-ASDKFIIAPESGIISVARGASLDPDLTQPRTLHYS 803

Query: 765 L-VIRAASPP----LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPA 818
           L V+     P    L   V V + + D+N+  PV  +   +    ++   VG    ++ A
Sbjct: 804 LNVVALDGAPGENQLQAGVTVNVTILDINNKNPVFYEPGSV--TMRENTAVGSVIAKLKA 861

Query: 819 YDADVTDKLQYRI 831
            D D T +L Y I
Sbjct: 862 KDLDKTAQLVYTI 874



 Score =  223 bits (545), Expect = 6e-56
 Identities = 230/834 (27%), Positives = 372/834 (44%), Gaps = 88/834 (10%)

Query: 13   VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAE-VEYTIELVTADTLN 71
            + D ND +P F    YE  + E A   T +  L +   ++  + + +  T +L      +
Sbjct: 373  ITDINDETPKFRSGYYECEIAENAPVNTPLTFLGSAMPEVYDHDQGINGTFQLYVKGASD 432

Query: 72   PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131
              +            +  F I  ++   L     ++ K   +T++ K   + +P  + + 
Sbjct: 433  VFEITPTKAIN----EATFMIRVKNSTFL---DYEKIKTINFTLVAKEIVKHNPKFNEVP 485

Query: 132  STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA--NSAIRY 189
              A    +I+D NDNYP+F++  Y V V E+  +     +A ++A D D G      IRY
Sbjct: 486  VVA----HILDRNDNYPEFTKNVYEVFVPENCDI--GATVAWVQALDDDSGVFGTMGIRY 539

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTL-----DYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
              + G+ Q   ++   +G +S VKT      D EQ+  + L + A+D        T QL+
Sbjct: 540  THLSGSIQHMLNLHPTTGIIS-VKTAGGPNWDREQISRHYLTVEARDDLGQGNRITVQLI 598

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGV-NAELTYTMTDKDYT 302
            INI DVNDN P F  + ++  + EN     + ++V+A DAD  G  N E+ Y++      
Sbjct: 599  INIEDVNDNPPIFTQNRYEARLLENKLDFENPLKVEARDADLNGTKNNEIEYSLF----- 653

Query: 303  GNVDLPITIDPRSGWVYTSGQLD--------RETQAKYQLLVTATDGGDPPRSATATXXX 354
            G++    TI+P +G +     +D        +++  +  L V A D G P   +      
Sbjct: 654  GDLSHNFTIEPSTGIIKPRTSIDFEALEGSLKDSIRQLHLTVRARDWGTPSLFSDVPLYI 713

Query: 355  XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGR 411
                       F    Y   + ED   GT ++ + A D D    +NR+ Y I  G +  +
Sbjct: 714  YVQDVNDHAPLFEYTFYNKSVPEDISGGTSILQVRAKDFDGSSPNNRIVYRIQNGAS-DK 772

Query: 412  FSITSQNGRGLITVAQPL----DFKQER--RYVLTVSATDS--GGRSDTAMVQINIT--D 461
            F I  ++G  +I+VA+      D  Q R   Y L V A D   G     A V +N+T  D
Sbjct: 773  FIIAPESG--IISVARGASLDPDLTQPRTLHYSLNVVALDGAPGENQLQAGVTVNVTILD 830

Query: 462  ANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS---EISNEA-- 516
             NN  PVF   P + ++ E+  +G+ +  + A D D    AQ+ Y+++    E  NE   
Sbjct: 831  INNKNPVFYE-PGSVTMRENTAVGSVIAKLKAKDLDK--TAQLVYTINPKFCEAKNERGI 887

Query: 517  -VAHHD----QQFVINPQTGAITTNKLLDRETMS----GYLLTVTARDGGVPSLSDTTDV 567
             +   D    + F ++P +G +T  + LDRE +     G ++  TA + G P +S TT +
Sbjct: 888  LLKLSDFNCAETFHLHPMSGVLTIAQQLDREMVEKVQMGLMVEDTASETG-PQISTTT-I 945

Query: 568  EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627
             I++ D+NDN P F+Q  Y  +I E++  G ++  V A DAD   N  I Y LD +    
Sbjct: 946  TINIEDINDNSPKFRQPYYKFSITENSKNGVTIGNVLAEDADK--NKTITYTLDGRFEIT 1003

Query: 628  GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687
                +D  SG +     +D E     +L   A D G P + S V + I+I D ND+ P F
Sbjct: 1004 ELIYLDSNSGDLVVANKIDHEIYDWLNLTIKATDSGIPARFSRVEIFIQILDENDNNPFF 1063

Query: 688  ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747
              +  +  ISE++P+G  +  I A D D G    + Y +        FS++    +D   
Sbjct: 1064 LGEPQSLLISEDTPVGRQVAIIEAKDADSGEFGKITYLLDRISSEGKFSID----ADSGI 1119

Query: 748  LVTMVDLDYESPRKKYELVIRA--------ASPPLWNDVR-VEILVTDVNDNAP 792
            L     LD E  +  Y LVI A         S    N  + + + + DVNDN P
Sbjct: 1120 LKVSDKLDREE-KHSYLLVIEAWDNYQYGFNSGESRNAFKHINVTILDVNDNHP 1172



 Score =  220 bits (538), Expect = 4e-55
 Identities = 248/944 (26%), Positives = 409/944 (43%), Gaps = 103/944 (10%)

Query: 13   VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72
            V D ND++P+F   Q   ++RE A+ G  + TL+ATD D G   +V Y ++ V  DT   
Sbjct: 149  VEDVNDNTPIFTSHQSSITLREDAAPG-VIATLEATDLDEGAYGQVVYQLQEV--DT--- 202

Query: 73   EDAXXXXXXXXXXVQDVFRIDGRSGALLTR--ASLDREKVARYTVLVKATDQASPVSDRL 130
                          + +F +    G  + R   SLD EK   + + V A D+A     R+
Sbjct: 203  -------------KESLFSVSTAGGKAIVRLVGSLDYEKQTLHQLKVLAVDRAK--QGRV 247

Query: 131  SS-TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            ++ TA + V + D  D  P+F   T    + E+  +  +  + ++ A D D G N+ I Y
Sbjct: 248  NTGTAALLVKVEDVEDQPPEFVRVTSVARIAENAPIGTS--VLQVTAIDGDRGVNNPILY 305

Query: 190  AIIGGNTQM---QFSIDSLSGDVSLVKTLDYEQVR----SYRLVIRAQDGG---SPSRSN 239
            ++   +       FS++  +G +   KTLD E +     +Y L I A + G    P  S 
Sbjct: 306  SLSSNSIDRITDVFSLEETTGTLLTAKTLDRESLSLSSGTYILQITATEYGGKIKPPPSV 365

Query: 240  TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRV-----QAYDADEGVNAELTY 294
            TT++ + I D+ND  P+F +  ++  ++EN P+   +  +     + YD D+G+N     
Sbjct: 366  TTEVTVIITDINDETPKFRSGYYECEIAENAPVNTPLTFLGSAMPEVYDHDQGINGTFQL 425

Query: 295  TMTDKDYTGNVDLPITIDPRSGW--VYTSGQLDRETQAKYQLLVTATD-GGDPPRSATAT 351
             +        +     I+  +    V  S  LD E        + A +     P+     
Sbjct: 426  YVKGASDVFEITPTKAINEATFMIRVKNSTFLDYEKIKTINFTLVAKEIVKHNPKFNEVP 485

Query: 352  XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE----DNRLHYEITGGN 407
                          F    YEV + E+   G  V  + A D D        + Y    G+
Sbjct: 486  VVAHILDRNDNYPEFTKNVYEVFVPENCDIGATVAWVQALDDDSGVFGTMGIRYTHLSGS 545

Query: 408  TRGRFSITSQNG-RGLITVAQP-LDFKQERRYVLTVSATDSGGRSDTAMVQ--INITDAN 463
             +   ++    G   + T   P  D +Q  R+ LTV A D  G+ +   VQ  INI D N
Sbjct: 546  IQHMLNLHPTTGIISVKTAGGPNWDREQISRHYLTVEARDDLGQGNRITVQLIINIEDVN 605

Query: 464  NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG--INAQITYSLSSEISNEAVAHHD 521
            +  P+F    Y A + E+       L V A D+D+    N +I YSL  ++S+       
Sbjct: 606  DNPPIFTQNRYEARLLENKLDFENPLKVEARDADLNGTKNNEIEYSLFGDLSH------- 658

Query: 522  QQFVINPQTGAITTNKLLDRETMSGYL--------LTVTARDGGVPSLSDTTDVEISVVD 573
              F I P TG I     +D E + G L        LTV ARD G PSL     + I V D
Sbjct: 659  -NFTIEPSTGIIKPRTSIDFEALEGSLKDSIRQLHLTVRARDWGTPSLFSDVPLYIYVQD 717

Query: 574  VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVI 632
            VND+ P+F+   Y  ++ ED   GTS+ QV A D D    N RI Y +  ++     F+I
Sbjct: 718  VNDHAPLFEYTFYNKSVPEDISGGTSILQVRAKDFDGSSPNNRIVYRI--QNGASDKFII 775

Query: 633  DPASGVIRTNKA------LDRESVATHDLKAVAIDG--GTPPQSSTVIVHIKIEDINDSP 684
             P SG+I   +       L +     + L  VA+DG  G     + V V++ I DIN+  
Sbjct: 776  APESGIISVARGASLDPDLTQPRTLHYSLNVVALDGAPGENQLQAGVTVNVTILDINNKN 835

Query: 685  PVF-ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL------ 737
            PVF E   +T  + EN+ +G+ I +++A D D+    V   + K  +  N   +      
Sbjct: 836  PVFYEPGSVT--MRENTAVGSVIAKLKAKDLDKTAQLVYTINPKFCEAKNERGILLKLSD 893

Query: 738  ----ETRQGSDKAELVTMV-DLDYESPRK-KYELVIR---AASPPLWNDVRVEILVTDVN 788
                ET      + ++T+   LD E   K +  L++    + + P  +   + I + D+N
Sbjct: 894  FNCAETFHLHPMSGVLTIAQQLDREMVEKVQMGLMVEDTASETGPQISTTTITINIEDIN 953

Query: 789  DNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSG--NNANLILLNETT 846
            DN+P  +     F+  ++       G V A DAD    + Y  L G      LI L+  +
Sbjct: 954  DNSPKFRQPYYKFSITENSKNGVTIGNVLAEDADKNKTITY-TLDGRFEITELIYLDSNS 1012

Query: 847  GSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITE 889
            G + ++ +++  +     + +  TD G+    + +++ ++++ E
Sbjct: 1013 GDLVVANKIDHEIYDWLNLTIKATDSGIPARFSRVEIFIQILDE 1056



 Score =  220 bits (538), Expect = 4e-55
 Identities = 228/839 (27%), Positives = 366/839 (43%), Gaps = 90/839 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V D  D  P F      A + E A  GT+VL + A D D G N  + Y++   + D +
Sbjct: 256  VKVEDVEDQPPEFVRVTSVARIAENAPIGTSVLQVTAIDGDRGVNNPILYSLSSNSIDRI 315

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA----RYTVLVKATDQASPV 126
                             DVF ++  +G LLT  +LDRE ++     Y + + AT+    +
Sbjct: 316  T----------------DVFSLEETTGTLLTAKTLDRESLSLSSGTYILQITATEYGGKI 359

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVI----AKIKATDADVG 182
                S T  + V I D ND  P+F    Y   + E+  V + P+     A  +  D D G
Sbjct: 360  KPPPSVTTEVTVIITDINDETPKFRSGYYECEIAENAPV-NTPLTFLGSAMPEVYDHDQG 418

Query: 183  ANSAIRYAIIGGNTQMQFSIDSLSGDVSL---VKT---LDYEQVRSYRLVIRAQDGGSPS 236
             N   +  + G +   + +      + +    VK    LDYE++++    + A++    +
Sbjct: 419  INGTFQLYVKGASDVFEITPTKAINEATFMIRVKNSTFLDYEKIKTINFTLVAKEIVKHN 478

Query: 237  -RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295
             + N   ++ +I D NDN P F  ++++  V EN  IG ++  VQA D D GV   +   
Sbjct: 479  PKFNEVPVVAHILDRNDNYPEFTKNVYEVFVPENCDIGATVAWVQALDDDSGVFGTMGIR 538

Query: 296  MTDKDYTGNVDLPITIDPRSG--WVYTSG--QLDRETQAKYQLLVTATDGGDPPRSATAT 351
             T    +G++   + + P +G   V T+G    DRE  +++ L V A D        T  
Sbjct: 539  YT--HLSGSIQHMLNLHPTTGIISVKTAGGPNWDREQISRHYLTVEARDDLGQGNRITVQ 596

Query: 352  XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD----EDNRLHYEITGGN 407
                          F   +YE  L E++      + + A DAD    ++N + Y + G  
Sbjct: 597  LIINIEDVNDNPPIFTQNRYEARLLENKLDFENPLKVEARDADLNGTKNNEIEYSLFGDL 656

Query: 408  TRGRFSITSQNGRGLITVAQPLDFK--------QERRYVLTVSATDSGGRS--DTAMVQI 457
            +    + T +   G+I     +DF+          R+  LTV A D G  S      + I
Sbjct: 657  SH---NFTIEPSTGIIKPRTSIDFEALEGSLKDSIRQLHLTVRARDWGTPSLFSDVPLYI 713

Query: 458  NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEA 516
             + D N++AP+FE   Y  SV ED   GT++L V A D D    N +I Y + +  S++ 
Sbjct: 714  YVQDVNDHAPLFEYTFYNKSVPEDISGGTSILQVRAKDFDGSSPNNRIVYRIQNGASDKF 773

Query: 517  VAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG--GVPSLSDTTDVEISVVDV 574
            +    +  +I+   GA     L    T+  Y L V A DG  G   L     V ++++D+
Sbjct: 774  II-APESGIISVARGASLDPDLTQPRTLH-YSLNVVALDGAPGENQLQAGVTVNVTILDI 831

Query: 575  NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK----DREEG-- 628
            N+  PVF +   +  + E+  VG+ ++++ A D D     ++ Y ++PK      E G  
Sbjct: 832  NNKNPVFYEP-GSVTMRENTAVGSVIAKLKAKDLD--KTAQLVYTINPKFCEAKNERGIL 888

Query: 629  ----------SFVIDPASGVIRTNKALDRESVATHDLKAVAID--GGTPPQSSTVIVHIK 676
                      +F + P SGV+   + LDRE V    +  +  D    T PQ ST  + I 
Sbjct: 889  LKLSDFNCAETFHLHPMSGVLTIAQQLDREMVEKVQMGLMVEDTASETGPQISTTTITIN 948

Query: 677  IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736
            IEDIND+ P F      F I+ENS  G TIG + A D D+  N  + Y++ G  +     
Sbjct: 949  IEDINDNSPKFRQPYYKFSITENSKNGVTIGNVLAEDADK--NKTITYTLDGRFEITEL- 1005

Query: 737  LETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAP 792
                  S+  +LV    +D+E       L I+A     P  ++ V + I + D NDN P
Sbjct: 1006 --IYLDSNSGDLVVANKIDHEI-YDWLNLTIKATDSGIPARFSRVEIFIQILDENDNNP 1061



 Score =  185 bits (450), Expect = 2e-44
 Identities = 159/556 (28%), Positives = 258/556 (46%), Gaps = 39/556 (7%)

Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
           +  P+G  I +++  D D      L++ +  +  +  + +   I P    VY + +LDRE
Sbjct: 64  KETPVGTLIYKLRGTDPD---GDPLSFGVRSQSGSDVIRVE-NISPTEADVYLNKELDRE 119

Query: 328 TQAKYQLLVTATDGG-DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386
           T+ +Y L++T TDG        T +              F   Q  + L ED  PG  + 
Sbjct: 120 TRDEYPLVLTLTDGRLGHGNYVTQSLLLLVEDVNDNTPIFTSHQSSITLREDAAPGV-IA 178

Query: 387 TLTATDADED--NRLHYEITGGNTR-GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443
           TL ATD DE    ++ Y++   +T+   FS+++  G+ ++ +   LD++++  + L V A
Sbjct: 179 TLEATDLDEGAYGQVVYQLQEVDTKESLFSVSTAGGKAIVRLVGSLDYEKQTLHQLKVLA 238

Query: 444 TDSG--GR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499
            D    GR  + TA + + + D  +  P F      A + E+APIGT+VL V+A D D G
Sbjct: 239 VDRAKQGRVNTGTAALLVKVEDVEDQPPEFVRVTSVARIAENAPIGTSVLQVTAIDGDRG 298

Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS----GYLLTVTARD 555
           +N  I YSLSS     ++      F +   TG + T K LDRE++S     Y+L +TA +
Sbjct: 299 VNNPILYSLSS----NSIDRITDVFSLEETTGTLLTAKTLDRESLSLSSGTYILQITATE 354

Query: 556 GG---VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT-----D 607
            G    P  S TT+V + + D+ND  P F+   Y   I E+A V T ++ +G+      D
Sbjct: 355 YGGKIKPPPSVTTEVTVIITDINDETPKFRSGYYECEIAENAPVNTPLTFLGSAMPEVYD 414

Query: 608 ADVGLNGRIH-YELDPKDREE--GSFVIDPASGVIRTNKA--LDRESVATHDLKAVAID- 661
            D G+NG    Y     D  E   +  I+ A+ +IR   +  LD E + T +   VA + 
Sbjct: 415 HDQGINGTFQLYVKGASDVFEITPTKAINEATFMIRVKNSTFLDYEKIKTINFTLVAKEI 474

Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
               P+ + V V   I D ND+ P F  +    ++ EN  IG T+  ++A D D G    
Sbjct: 475 VKHNPKFNEVPVVAHILDRNDNYPEFTKNVYEVFVPENCDIGATVAWVQALDDDSGVFGT 534

Query: 722 --VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR 779
             + Y+   G   +  +L    G    +     + D E   + Y  V         N + 
Sbjct: 535 MGIRYTHLSGSIQHMLNLHPTTGIISVKTAGGPNWDREQISRHYLTVEARDDLGQGNRIT 594

Query: 780 VEILVT--DVNDNAPV 793
           V++++   DVNDN P+
Sbjct: 595 VQLIINIEDVNDNPPI 610



 Score =  177 bits (431), Expect = 4e-42
 Identities = 205/771 (26%), Positives = 334/771 (43%), Gaps = 65/771 (8%)

Query: 170 VIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA 229
           +I K++ TD D    S    +  G +     +I     DV L K LD E    Y LV+  
Sbjct: 71  LIYKLRGTDPDGDPLSFGVRSQSGSDVIRVENISPTEADVYLNKELDRETRDEYPLVLTL 130

Query: 230 QDGGSPSRSNTTQ-LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV 288
            DG     +  TQ LL+ + DVNDN P F +     ++ E+   G  I  ++A D DEG 
Sbjct: 131 TDGRLGHGNYVTQSLLLLVEDVNDNTPIFTSHQSSITLREDAAPGV-IATLEATDLDEGA 189

Query: 289 NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348
             ++ Y + + D   ++   ++       V   G LD E Q  +QL V A D     R  
Sbjct: 190 YGQVVYQLQEVDTKESL-FSVSTAGGKAIVRLVGSLDYEKQTLHQLKVLAVDRAKQGRVN 248

Query: 349 TATXXXXXXXXXXXXX--XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEIT 404
           T T                F+       +AE+ P GT V+ +TA D D   +N + Y ++
Sbjct: 249 TGTAALLVKVEDVEDQPPEFVRVTSVARIAENAPIGTSVLQVTAIDGDRGVNNPILYSLS 308

Query: 405 GGNTRGRFSITS-QNGRGLITVAQPLDFKQ----ERRYVLTVSATDSGGR-----SDTAM 454
             +      + S +   G +  A+ LD +        Y+L ++AT+ GG+     S T  
Sbjct: 309 SNSIDRITDVFSLEETTGTLLTAKTLDRESLSLSSGTYILQITATEYGGKIKPPPSVTTE 368

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT-----DSDVGINAQITYSLS 509
           V + ITD N+  P F +  Y   + E+AP+ T +  + +      D D GIN   T+ L 
Sbjct: 369 VTVIITDINDETPKFRSGYYECEIAENAPVNTPLTFLGSAMPEVYDHDQGING--TFQLY 426

Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNK--LLDRETMSGYLLTVTARD--GGVPSLSDTT 565
            + +++ V        IN  T  I       LD E +     T+ A++     P  ++  
Sbjct: 427 VKGASD-VFEITPTKAINEATFMIRVKNSTFLDYEKIKTINFTLVAKEIVKHNPKFNEVP 485

Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625
            V   ++D NDN P F + +Y   + E+  +G +V+ V A D D G+ G +         
Sbjct: 486 -VVAHILDRNDNYPEFTKNVYEVFVPENCDIGATVAWVQALDDDSGVFGTMGIRYTHLSG 544

Query: 626 E-EGSFVIDPASGVIRTNKA----LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680
             +    + P +G+I    A     DRE ++ H L   A D        TV + I IED+
Sbjct: 545 SIQHMLNLHPTTGIISVKTAGGPNWDREQISRHYLTVEARDDLGQGNRITVQLIINIEDV 604

Query: 681 NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG--PNAVVHYSIKGGDDSNSFSLE 738
           ND+PP+F  +     + EN        ++ A D D     N  + YS+ G D S++F++E
Sbjct: 605 NDNPPIFTQNRYEARLLENKLDFENPLKVEARDADLNGTKNNEIEYSLFG-DLSHNFTIE 663

Query: 739 TRQGSDKAELVTMVDLD-----YESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDN 790
              G  K    T +D +      +   ++  L +RA    +P L++DV + I V DVND+
Sbjct: 664 PSTGIIKPR--TSIDFEALEGSLKDSIRQLHLTVRARDWGTPSLFSDVPLYIYVQDVNDH 721

Query: 791 APVMKDFQIIFNNY---KDCFPVGPFGRVPAYDAD---VTDKLQYRILSGNNANLILLNE 844
           AP+   F+  F N    +D        +V A D D     +++ YRI +G +   I+  E
Sbjct: 722 APL---FEYTFYNKSVPEDISGGTSILQVRAKDFDGSSPNNRIVYRIQNGASDKFIIAPE 778

Query: 845 T-----TGSMTLSPQLNTNVPKLATMEVSVTDGV---NEIKAMMQLSVRLI 887
           +         +L P L        ++ V   DG    N+++A + ++V ++
Sbjct: 779 SGIISVARGASLDPDLTQPRTLHYSLNVVALDGAPGENQLQAGVTVNVTIL 829



 Score =  172 bits (419), Expect = 1e-40
 Identities = 183/704 (25%), Positives = 299/704 (42%), Gaps = 73/704 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            IN+ D ND+SP F    Y+ S+ E + +G T+  + A D D  KN  + YT++       
Sbjct: 947  INIEDINDNSPKFRQPYYKFSITENSKNGVTIGNVLAEDAD--KNKTITYTLD------- 997

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           + ++  +D  SG L+    +D E      + +KATD   P     
Sbjct: 998  -----------GRFEITELIYLDSNSGDLVVANKIDHEIYDWLNLTIKATDSGIPAR--- 1043

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             S   I + I+D+NDN P F  +  ++ + ED  V     +A I+A DAD G    I Y 
Sbjct: 1044 FSRVEIFIQILDENDNNPFFLGEPQSLLISEDTPVGRQ--VAIIEAKDADSGEFGKITYL 1101

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG------GSPSRSNTTQLL 244
            +   +++ +FSID+ SG + +   LD E+  SY LVI A D          SR+    + 
Sbjct: 1102 LDRISSEGKFSIDADSGILKVSDKLDREEKHSYLLVIEAWDNYQYGFNSGESRNAFKHIN 1161

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG--VNAELTYTMTDKDYT 302
            + I DVNDN P+ +   +  +++E    G +I    A DAD+    N ++   ++D +  
Sbjct: 1162 VTILDVNDNHPQLHVPPYCVNITEFHEPGQAITTFHASDADDPNTSNGQVIIDISDGNQK 1221

Query: 303  GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
                L   I   S  + T+  L R     Y L++ A D G P                  
Sbjct: 1222 NFFALS-QISEWSAELRTTTSL-RGRHGNYTLIIRAQDLGTPSHLIEEPLHICVTDFNDH 1279

Query: 363  XXXFM--PGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQN 418
               F+  P    + + E+   G+ +V + ATD D  +   + Y +         S   Q 
Sbjct: 1280 PPTFVTPPHNSTLRVPENATIGSALVKIIATDEDVGSNGIVRYRLKADPAGHWKSFNLQP 1339

Query: 419  GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTA 476
              G++ +  PLD K+++ Y + + A D G    S    + + +++ N+Y P F    +T 
Sbjct: 1340 VSGILELRLPLDRKKQKVYDIRIEAYDLGVPSLSSDLDLTVYVSNINDYQPQFMGDEFTV 1399

Query: 477  SVFEDAPIGTTVLVVSAT-DSDV----GINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
            +  E+ P       +  T D D     G  A I Y +     NE     +  F ++P   
Sbjct: 1400 NFTENKPSEVERQKLPQTVDRDELEFDGPFAPICYFIVG--GNE-----NGLFKLHPVEH 1452

Query: 532  AITTNKLLDRETMSGYLLTVTA-RDGGVP----SLSDTTD-----VEISVVDVNDNEPVF 581
             +T ++ LDRE    +LL V A  D   P    S  D++D     V + V+DVNDN P F
Sbjct: 1453 ILTVSRPLDREEKDTHLLLVKATEDCTKPPRNESFFDSSDDTQLKVIVKVLDVNDNAPQF 1512

Query: 582  KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK----------DREEGSFV 631
              +++T  +      GT+  +V A DAD+  N R+ Y L  K          D +   F+
Sbjct: 1513 IHRVFTGGVSTATSFGTTFMEVKAEDADLDDNARMSYFLIGKVQMTLTEGLEDLKRDPFL 1572

Query: 632  IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675
            +D  +G ++ N           D   +  D G     + V +++
Sbjct: 1573 VDRDTGAVQLNFDPQEGMKGYFDFMVLVNDTGGLQDMARVFIYL 1616


>UniRef50_Q967F4 Cluster: Cadherin-related hmr-1 precursor; n=3;
            Caenorhabditis|Rep: Cadherin-related hmr-1 precursor -
            Caenorhabditis elegans
          Length = 2920

 Score =  258 bits (633), Expect = 1e-66
 Identities = 254/928 (27%), Positives = 404/928 (43%), Gaps = 80/928 (8%)

Query: 3    VPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
            + FC    + V+D ND+SP FE   YE SV    + GT+V+T+ A D D   NAE+ Y++
Sbjct: 960  IGFC-QFSVEVVDINDNSPQFERPSYETSVSRFEAVGTSVITVFAFDNDAAHNAEITYSL 1018

Query: 63   ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122
            E+   DT   E+             D F +  R    +T       K  ++   V A D 
Sbjct: 1019 EI---DTTAGEEHQNDL--------DFFELVNRRSGEITLIKPIPMKTQKFIFNVIADDN 1067

Query: 123  ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT---VSVDEDISVTDNPVIAKIKATDA 179
              P  + L S+A + +N++D     P++         ++VDE++ +  N VI + +A  +
Sbjct: 1068 GIP--EALQSSAQVTLNVLDKQQKAPKWQTSPDCKPGITVDENVEL--NKVILRCRAVSS 1123

Query: 180  DVGANSAIRYAII-----GGNTQMQF-SIDSLSG-----DVSLVKTLDYEQVRSYRLVIR 228
                NS + Y +      G   + +F   +         +V +++ LDYEQV +Y L + 
Sbjct: 1124 GDSRNSDVIYKLTASGGPGNKAESKFRQFNKFENGNEWVEVVIMEGLDYEQVNNYTLTLT 1183

Query: 229  AQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENV--------PIGYSIVRVQ 280
            A D  S   S  T  ++ +RDVND  P+F   LF  ++ E +          G  IV V+
Sbjct: 1184 ATDMTSRVASTKT-FVVEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVK 1242

Query: 281  AYDAD-EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTAT 339
            A D D +G   E+ Y +   +  G       ID  +G ++ + + DRE    Y L V A+
Sbjct: 1243 AIDTDSDGPQNEVHYRIVG-EANGEETKHFRIDELTGEIFPNEKFDREKIDMYILTVEAS 1301

Query: 340  D-------GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392
            D       G + P                    F   +Y   + E E  G  V+T+ A D
Sbjct: 1302 DRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHD 1361

Query: 393  ADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT 452
             D+ + L Y + G    GR     +   G I V +PLDF+   +Y L + A+D G  + T
Sbjct: 1362 LDKHSNLRYHLIGAG-GGRIPFGVRTDSGTIFVKEPLDFEASDQYHLVLIASD-GRHNAT 1419

Query: 453  AMVQINITDANNYAPVFENAPYTASVF-EDAPIGTTVLVVSATDSDVG-INAQITYSLSS 510
              V I+I D N+ AP FE   Y  +V  ED  I   +  V ATD+D    +++I Y L  
Sbjct: 1420 TNVYIHIEDVNDNAPQFEQQKYATTVIEEDVDIPKVLFNVHATDADQDEKSSRIVYRLEG 1479

Query: 511  EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG---YLLTVTARDGGVPSLSDTTDV 567
            + +       D+ F I   +G I   K LDR+  +G   +   V A D     L    DV
Sbjct: 1480 QGA-------DEVFRIGKYSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGLVGYADV 1532

Query: 568  EISVVDVNDNEPVFKQQLY---TANIMEDALVGTSVSQVGATDAD--VGLNGRIHYEL-- 620
            +++V D+NDN P+F ++L+     N       G     V A D D     N  I Y +  
Sbjct: 1533 QVNVRDINDNSPIFPERLFGYIEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVR 1592

Query: 621  DPKDREEGSFVIDPASGVIRTNKALDRESVATHD--LKAVAIDGGTPPQSSTVIVHIKIE 678
            +     E  F ID  +G I   ++LDRE  +  +  ++  A D G P +     V IK+ 
Sbjct: 1593 NKLINGESVFRIDQNTGKIFAMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIKVT 1652

Query: 679  DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738
            D+ND+ P FE       + E +PIG  +    A D DE     V ++ +  ++S+ F + 
Sbjct: 1653 DMNDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDADEEAKDNV-FTYQLSEESDYFYVT 1711

Query: 739  TRQGSDKAE---LVTMVDLDYE--SPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPV 793
            T + S ++    L     LDYE  + R  + L IR +      +  V + + D ND+AP 
Sbjct: 1712 TDKDSKQSSVGVLRVKQPLDYEDVTQRDGFHLGIRVSDGRHDAEAAVHVALVDRNDHAPH 1771

Query: 794  MKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLS 852
            +       +  ++  P G   GR  A D D  D  ++RI   ++       +  G++ ++
Sbjct: 1772 IHG--ATEHRVREDVPRGTSIGRYTATDRDAGDTARFRINRQSDPKRQFTIDQDGTLRVA 1829

Query: 853  PQLNTNVPKLATMEVSVTDGVNEIKAMM 880
              L+     +  + +   D  N I   M
Sbjct: 1830 HTLDREDIAVYNLIIEAYDNSNNIGRQM 1857



 Score =  243 bits (594), Expect = 6e-62
 Identities = 354/1379 (25%), Positives = 560/1379 (40%), Gaps = 160/1379 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGAS--------SGTTVLTLKATDQDI-GKNAEVEYT 61
            + V D ND  P F +  +  ++ E  +        +G  ++T+KA D D  G   EV Y 
Sbjct: 1199 VEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYR 1258

Query: 62   IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121
            I        N E+               FRID  +G +      DREK+  Y + V+A+D
Sbjct: 1259 I----VGEANGEETKH------------FRIDELTGEIFPNEKFDREKIDMYILTVEASD 1302

Query: 122  Q---ASPVSDRLSS-TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKAT 177
            +   A P ++  +     + + I D NDN P F E+ Y   V E  S  +   +  IKA 
Sbjct: 1303 RSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKE--SEGEGHDVITIKAH 1360

Query: 178  DADVGANSAIRYAIIG-GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS 236
            D D  +N  +RY +IG G  ++ F + + SG + + + LD+E    Y LV+ A DG    
Sbjct: 1361 DLDKHSN--LRYHLIGAGGGRIPFGVRTDSGTIFVKEPLDFEASDQYHLVLIASDG---R 1415

Query: 237  RSNTTQLLINIRDVNDNAPRFYTSLFQESV-SENVPIGYSIVRVQAYDADEGV-NAELTY 294
             + TT + I+I DVNDNAP+F    +  +V  E+V I   +  V A DAD+   ++ + Y
Sbjct: 1416 HNATTNVYIHIEDVNDNAPQFEQQKYATTVIEEDVDIPKVLFNVHATDADQDEKSSRIVY 1475

Query: 295  TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA---KYQLLVTATDGGDPPRSATAT 351
             +  +      D    I   SG +     LDR+  A    +  +V A D         A 
Sbjct: 1476 RLEGQ----GADEVFRIGKYSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGLVGYAD 1531

Query: 352  XXXXXXXXXXXXXXFMPGQYEVELAEDEPP----GTPVVTLTATDADEDNRLHYEITGGN 407
                          F P +    + E+  P    G   + + A D D+    +  I  G 
Sbjct: 1532 VQVNVRDINDNSPIF-PERLFGYIEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGI 1590

Query: 408  TRGR-------FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQIN 458
             R +       F I    G+     +   +   ER +++ V A D G   R   A V I 
Sbjct: 1591 VRNKLINGESVFRIDQNTGKIFAMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIK 1650

Query: 459  ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI-TYSLSSEISNEAV 517
            +TD N+ AP FE   Y  SV E APIG  V+  SA D+D      + TY LS E S+   
Sbjct: 1651 VTDMNDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDADEEAKDNVFTYQLSEE-SDYFY 1709

Query: 518  AHHDQQFVINPQTGAITTNKLLDRETMS---GYLLTVTARDGGVPSLSDTTDVEISVVDV 574
               D+        G +   + LD E ++   G+ L +   DG   +      V +++VD 
Sbjct: 1710 VTTDKDSK-QSSVGVLRVKQPLDYEDVTQRDGFHLGIRVSDGRHDA---EAAVHVALVDR 1765

Query: 575  NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR--IHYELDPKDREEGSFVI 632
            ND+ P          + ED   GTS+ +  ATD D G   R  I+ + DPK +    F I
Sbjct: 1766 NDHAPHIHGAT-EHRVREDVPRGTSIGRYTATDRDAGDTARFRINRQSDPKRQ----FTI 1820

Query: 633  DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692
            D   G +R    LDRE +A ++L   A D         V V++  +D+ND+ P   +   
Sbjct: 1821 DQ-DGTLRVAHTLDREDIAVYNLIIEAYDNSNNIGRQMVAVYL--QDVNDNGPEPYTVPR 1877

Query: 693  TFYISENSPIGTT-IGEIRAHDPDE---GP--NAVVHYSIKGGDDSNS-FSLETRQGSDK 745
                 EN+P+      EIRA D D    GP     V  S K     N  F+     G+  
Sbjct: 1878 PCIFRENTPVNQLGTCEIRATDRDTAEFGPPFTMEVSPSFKYSQYLNVIFNANGDGGNGS 1937

Query: 746  AELVTMVDLDYESP--RKKYEL-VIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN 802
              +  + + D E+P   K  E+ +I A      N+  V +++ D+NDN        I  N
Sbjct: 1938 MTITPLQEFDREAPVPGKILEIPLILADRAGRRNEASVHVIIGDLNDNTMHDGRMTIHVN 1997

Query: 803  NYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKL 862
            +Y         GRV   DAD  D L  +  S  ++         GS+T++ ++       
Sbjct: 1998 SYLGRLKETVIGRVYVDDADDWD-LGDKTFSWKDSRPGFELSDKGSITMAGEMAAGT--- 2053

Query: 863  ATMEVSVTDGVNEIKAM--MQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGL 920
             TM  +V D   +  A+  + + V  + +    N  +V+L  + AE+    L   FI   
Sbjct: 2054 YTMSANVHDNARDEDAVGYVTVIVNAVPQIAFDNQGSVQL--LIAEETPLQLPDDFIRAD 2111

Query: 921  A---AIIPCPKENIYIFSVQDDT-DVTGNILNVSFSARR--PDAEVGVAGDPSPHYSPTH 974
            +   +++   K+ +  +   D T DV    + ++    R  P   V      S +     
Sbjct: 2112 SNGQSLMDTFKQEMTAYMGGDVTVDVFSVQVGIATLQTRDVPVLNVRFNARGSTYRDTAQ 2171

Query: 975  LRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFR 1034
            L   +  HR  L R   V+++    ++C    C     C T+         V+++S +  
Sbjct: 2172 LNGLIAAHRADLQRKLNVEIVGVGIDMCKFTQC--DAGCQTLNSADYDGIVVSANSTVIV 2229

Query: 1035 PIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG--GILCQGC 1092
             +   +   C CP       C+  L    C  DG       G  C  R +G  G  CQG 
Sbjct: 2230 GVNATSRDDCTCPVWRAPPACQHSL----CHNDGVCHNTNPGFFCECRNDGLKGARCQG- 2284

Query: 1093 SIDAAYTTAVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRY---- 1148
                  TT       RSF  + F  +  +     +++   F T  +  LL YNG      
Sbjct: 2285 ------TT-------RSFGGNGFAWYKPMPACTSLNISFSFMTTQSDALLFYNGPLETLR 2331

Query: 1149 NERH----DFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGN-VGDGSWHTVEIEY 1203
            N+ H    D++ ++L      RGG   L  S + G  +S + V    + DG+WH + +  
Sbjct: 2332 NDTHIEYSDYIFIQL------RGGRISLEVSMN-GQSRSSLEVASTALNDGTWHDISVNQ 2384

Query: 1204 FNRTITMILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQ 1263
              + + +++D+C + L  AGA D     +C          R E+ T      L++  P+Q
Sbjct: 2385 EGKRVELVVDNC-RFLG-AGADD----SSC----------RAELYTPDDDERLNIVTPVQ 2428

Query: 1264 IGGLPNIPSS---FQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSS 1319
            IGGL  +        +      GC+ +  ++    DL +   +  +  GC    + C S
Sbjct: 2429 IGGLAPLSGQDYPQTIPRAGLNGCVRNLNVNGDQYDLATPAFEQNSEKGCRLWGATCDS 2487



 Score =  212 bits (518), Expect = 1e-52
 Identities = 254/917 (27%), Positives = 386/917 (42%), Gaps = 107/917 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I + D ND+ P F    Y A VRE      T+L + A D+D G N+ + Y++        
Sbjct: 630  IRIDDVNDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKDTGDNSRITYSV-------- 681

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
               D           +    R+D         A    E+   Y   V A D   PVS  L
Sbjct: 682  ---DNHNFSINSNGEISAKVRLD---------ADQLNERHFVYRFNVTARDHGEPVS--L 727

Query: 131  SSTATIHVNIIDDNDNYPQF-SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            SS+A IH+   + ND    F     YT  V ED +    PVI +I+A DAD      + Y
Sbjct: 728  SSSAMIHIRTENTNDESAVFLPTSQYTAFVAED-AQGGTPVI-QIQARDAD---RDEVTY 782

Query: 190  AII---GGNTQMQ--FSIDSLSGDVSL---VKTLDYEQVRS-YRLVIRAQDGGS----PS 236
            + +   G +TQ    FSID  +G V L   V   D  +  +   L +  QD GS    PS
Sbjct: 783  SFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPS 842

Query: 237  RSNTT--QLLINIRDVNDNAPRFYTSLFQESVSENVPIGY-----SIVRVQAYDADEGVN 289
            +++T+   LLI I DVN+N P F        +++ +   Y     +IV+V+A D D   N
Sbjct: 843  KTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSAN 902

Query: 290  AELTYTMTDKDYTGNVD-LPITIDPRSGWVYTSGQL--DRETQAKYQLLVTATDGGDPPR 346
             ++ Y++    YT +       ID ++G +  S  +  DRET+ +  + V ATD GD P 
Sbjct: 903  GDIVYSLY---YTQSESRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRGDRPL 959

Query: 347  SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR------LH 400
                               F    YE  ++  E  GT V+T+ A D D  +       L 
Sbjct: 960  IGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGTSVITVFAFDNDAAHNAEITYSLE 1019

Query: 401  YEITGG----NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG---GRSDTA 453
             + T G    N    F + ++   G IT+ +P+  K + +++  V A D+G       +A
Sbjct: 1020 IDTTAGEEHQNDLDFFELVNRRS-GEITLIKPIPMKTQ-KFIFNVIADDNGIPEALQSSA 1077

Query: 454  MVQINITDANNYAPVFENAPYT---ASVFEDAPIGTTVLVVSATDSDVGINAQITYSL-- 508
             V +N+ D    AP ++ +P      +V E+  +   +L   A  S    N+ + Y L  
Sbjct: 1078 QVTLNVLDKQQKAPKWQTSPDCKPGITVDENVELNKVILRCRAVSSGDSRNSDVIYKLTA 1137

Query: 509  SSEISNEAVAHHDQ--QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566
            S    N+A +   Q  +F    +   +   + LD E ++ Y LT+TA D     ++ T  
Sbjct: 1138 SGGPGNKAESKFRQFNKFENGNEWVEVVIMEGLDYEQVNNYTLTLTATD-MTSRVASTKT 1196

Query: 567  VEISVVDVNDNEPVFKQQLYTANIMEDALV--------GTSVSQVGATDADV-GLNGRIH 617
              + V DVND  P F   L+T  I E+           G  +  V A D D  G    +H
Sbjct: 1197 FVVEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVH 1256

Query: 618  YEL--DPKDREEGSFVIDPASGVIRTNKALDRE-------SVATHDLKAVAIDGGTPPQS 668
            Y +  +    E   F ID  +G I  N+  DRE       +V   D    A+ G   P  
Sbjct: 1257 YRIVGEANGEETKHFRIDELTGEIFPNEKFDREKIDMYILTVEASDRSVSALPGANGPNK 1316

Query: 669  STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
              V V I I D+ND+ P FE       + E+   G  +  I+AHD D+  N   H  I  
Sbjct: 1317 DNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHDLDKHSNLRYHL-IGA 1375

Query: 729  GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVN 788
            G     F + T    D   +     LD+E+   +Y LV+ A+         V I + DVN
Sbjct: 1376 GGGRIPFGVRT----DSGTIFVKEPLDFEA-SDQYHLVLIASDGRHNATTNVYIHIEDVN 1430

Query: 789  DNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADVTDK---LQYRILSGNNANLIL-LN 843
            DNAP  +  +      ++   +      V A DAD  +K   + YR L G  A+ +  + 
Sbjct: 1431 DNAPQFEQQKYATTVIEEDVDIPKVLFNVHATDADQDEKSSRIVYR-LEGQGADEVFRIG 1489

Query: 844  ETTGSMTLSPQLNTNVP 860
            + +G++ L   L+ + P
Sbjct: 1490 KYSGTIELVKALDRDPP 1506



 Score =  200 bits (487), Expect = 6e-49
 Identities = 212/752 (28%), Positives = 327/752 (43%), Gaps = 63/752 (8%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            F +D +SG + T  S   E+   Y +  +A D  SP  +  S  + + +  I  ++  PQ
Sbjct: 472  FIVDPKSGVVRTGWS-KYERGDTYRISAQAMD-LSPSDNTTSQLSEVAILEILADERPPQ 529

Query: 150  FSEKTYTVSVDEDISVTDNPVIAKIKATDA--DVGANSAIRYAIIGGNTQMQ---FSIDS 204
            F+++ Y V+V ED  V  + V  K ++  +  D  +   I Y++ G   + +   F ID 
Sbjct: 530  FAKQEYEVTVSEDNLVDYSVVDVKAQSFRSFEDGRSKGPITYSLEGDTPEDETKWFRIDP 589

Query: 205  LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
             +G + L + LD++     +L          +R +   L I I DVNDN P F   L+  
Sbjct: 590  STGIIHLTRLLDFDDPALPKLHKLKVTAREDNRESHVDLTIRIDDVNDNVPTFTRPLYTA 649

Query: 265  SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
             V E++P+  +I++V A D D G N+ +TY++ + +++ N +  I+   R      + QL
Sbjct: 650  QVREDIPLNQTILKVTAVDKDTGDNSRITYSVDNHNFSINSNGEISAKVR----LDADQL 705

Query: 325  DRETQAKYQLLVTATDGGDP-PRSATATXXXXXXXXXXXXXXFMP-GQYEVELAEDEPPG 382
            + E    Y+  VTA D G+P   S++A               F+P  QY   +AED   G
Sbjct: 706  N-ERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTNDESAVFLPTSQYTAFVAEDAQGG 764

Query: 383  TPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNGRGLITVAQPLD----FKQERR 436
            TPV+ + A DAD D   +   +  G +T+     +     GL+ +   +      + E  
Sbjct: 765  TPVIQIQARDADRDEVTYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENP 824

Query: 437  YVLTVSATDSGG--------RSDTAMVQINITDANNYAPVFEN-APYT--ASVFEDA--P 483
              LTV   D G          +  A + I I D NN  P F + A Y+  A + E     
Sbjct: 825  INLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAKIMEGTYKT 884

Query: 484  IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK--LLDR 541
               T++ V ATD D   N  I YSL    S    A     FVI+ QTG +T +   + DR
Sbjct: 885  DPPTIVKVEATDDDSSANGDIVYSLYYTQSESRKA-----FVIDRQTGVLTPSPHVVFDR 939

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
            ET     +TV A D G   L       + VVD+NDN P F++  Y  ++     VGTSV 
Sbjct: 940  ETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGTSVI 999

Query: 602  QVGATDADVGLNGRIHY--ELDPKDREEGS------FVIDPASGVIRTNKALDRESVATH 653
             V A D D   N  I Y  E+D    EE         +++  SG I   K +  ++    
Sbjct: 1000 TVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSGEITLIKPIPMKT-QKF 1058

Query: 654  DLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPVFES--DCLT-FYISENSPIGTTIGEI 709
                +A D G P    S+  V + + D     P +++  DC     + EN  +   I   
Sbjct: 1059 IFNVIADDNGIPEALQSSAQVTLNVLDKQQKAPKWQTSPDCKPGITVDENVELNKVILRC 1118

Query: 710  RAHDPDEGPNAVVHYSI-KGGDDSNSFSLETRQ------GSDKAELVTMVDLDYESPRKK 762
            RA    +  N+ V Y +   G   N    + RQ      G++  E+V M  LDYE     
Sbjct: 1119 RAVSSGDSRNSDVIYKLTASGGPGNKAESKFRQFNKFENGNEWVEVVIMEGLDYEQV-NN 1177

Query: 763  YELVIRAA--SPPLWNDVRVEILVTDVNDNAP 792
            Y L + A   +  + +     + V DVND  P
Sbjct: 1178 YTLTLTATDMTSRVASTKTFVVEVRDVNDVVP 1209



 Score =  197 bits (480), Expect = 4e-48
 Identities = 235/890 (26%), Positives = 384/890 (43%), Gaps = 100/890 (11%)

Query: 17   NDHSPVFEMQQYEASVREGASSGTTVLTLKATD----QDIGKNAEVEYTIELVTADTLNP 72
            ++  P F  Q+YE +V E      +V+ +KA      +D      + Y++E    DT  P
Sbjct: 524  DERPPQFAKQEYEVTVSEDNLVDYSVVDVKAQSFRSFEDGRSKGPITYSLE---GDT--P 578

Query: 73   EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132
            ED               FRID  +G +     LD +  A    L K   + +   D   S
Sbjct: 579  EDETKW-----------FRIDPSTGIIHLTRLLDFDDPA-LPKLHKL--KVTAREDNRES 624

Query: 133  TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192
               + + I D NDN P F+   YT  V EDI +  N  I K+ A D D G NS I Y++ 
Sbjct: 625  HVDLTIRIDDVNDNVPTFTRPLYTAQVREDIPL--NQTILKVTAVDKDTGDNSRITYSVD 682

Query: 193  GGNTQMQFSIDSLSGDVSLVKTLDYEQVRS----YRLVIRAQDGGSP-SRSNTTQLLINI 247
              N    FSI+S +G++S    LD +Q+      YR  + A+D G P S S++  + I  
Sbjct: 683  NHN----FSINS-NGEISAKVRLDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRT 737

Query: 248  RDVNDNAPRFY-TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
             + ND +  F  TS +   V+E+   G  ++++QA DAD     E+TY+  DK+      
Sbjct: 738  ENTNDESAVFLPTSQYTAFVAEDAQGGTPVIQIQARDADRD---EVTYSFMDKNGRSTQK 794

Query: 307  LPI-TIDPRSGWVY----TSGQLDRETQAKYQLLVTATDGGD----PPRSAT--ATXXXX 355
            + + +ID  +G V      S     E +    L V   D G     P ++ T  AT    
Sbjct: 795  MNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIG 854

Query: 356  XXXXXXXXXXFMPGQYEVELA-------EDEPPGTPVVTLTATDADEDNRLHYEITGGNT 408
                      F       ++A       + +PP    V  T  D+  +  + Y +    +
Sbjct: 855  IEDVNNNKPEFPDCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANGDIVYSLYYTQS 914

Query: 409  RGRFSITSQNGRGLITVAQPLDFKQER--RYVLTVSATDSGGRSDTAMVQ--INITDANN 464
              R +       G++T +  + F +E   R  +TV ATD G R      Q  + + D N+
Sbjct: 915  ESRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDIND 974

Query: 465  YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524
             +P FE   Y  SV     +GT+V+ V A D+D   NA+ITYSL  + +      +D  F
Sbjct: 975  NSPQFERPSYETSVSRFEAVGTSVITVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDF 1034

Query: 525  --VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVF 581
              ++N ++G IT  K +  +T   ++  V A D G+P +L  +  V ++V+D     P +
Sbjct: 1035 FELVNRRSGEITLIKPIPMKTQK-FIFNVIADDNGIPEALQSSAQVTLNVLDKQQKAPKW 1093

Query: 582  KQQ---LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL----DPKDREEGSF---- 630
            +          + E+  +   + +  A  +    N  + Y+L     P ++ E  F    
Sbjct: 1094 QTSPDCKPGITVDENVELNKVILRCRAVSSGDSRNSDVIYKLTASGGPGNKAESKFRQFN 1153

Query: 631  VIDPASGVIRT--NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688
              +  +  +     + LD E V  + L   A D  T   +ST    +++ D+ND  P F 
Sbjct: 1154 KFENGNEWVEVVIMEGLDYEQVNNYTLTLTATD-MTSRVASTKTFVVEVRDVNDVVPQFT 1212

Query: 689  SDCLTFYISE----NSPIGTTIGE----IRAHDPD-EGPNAVVHYSIKG---GDDSNSFS 736
             D  T  I E    N  +  T G+    ++A D D +GP   VHY I G   G+++  F 
Sbjct: 1213 VDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEETKHFR 1272

Query: 737  LETRQG----SDK--AELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDN 790
            ++   G    ++K   E + M  L  E+  +     +  A+ P  ++V+V+I++ DVNDN
Sbjct: 1273 IDELTGEIFPNEKFDREKIDMYILTVEASDRSVS-ALPGANGPNKDNVKVQIVINDVNDN 1331

Query: 791  APVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANL 839
            AP  ++ Q      K+    G     + A+D D    L+Y ++      +
Sbjct: 1332 APSFEE-QKYIGRVKESEGEGHDVITIKAHDLDKHSNLRYHLIGAGGGRI 1380



 Score =  101 bits (243), Expect = 2e-19
 Identities = 120/489 (24%), Positives = 215/489 (43%), Gaps = 45/489 (9%)

Query: 389 TATDADEDNRLHYEITGGNTRGRFSITSQ----NGRGLITVAQPLDFKQERRYVLTVSAT 444
           T  +  E   +   +  G T G  ++  +    +  G I + +PL++++    + TV   
Sbjct: 340 TTMEDIEKKDMKIPLFAGETIGEINVAKEWLKIDDDGKIHLLKPLNYEKTSSIIATVPIN 399

Query: 445 DSGGRSDTAMVQINITDANNYAPVFENAPYT--ASVFEDAPIGTTVLVVSATDSDVGINA 502
                + T  ++I++ D +   P F N+P    A V  +  IG  V    A D     ++
Sbjct: 400 GLQS-TRTQTIRIHVADIDE-PPSFVNSPLPMLAVVPLNPTIGRIVYQFVARDEHGDGDS 457

Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
            + Y     I   +       F+++P++G + T      E    Y ++  A D   PS +
Sbjct: 458 NVLYKTIDVIPAGS-------FIVDPKSGVVRTG-WSKYERGDTYRISAQAMDLS-PSDN 508

Query: 563 DTTDV-EISVVDV--NDNEPVFKQQLYTANIMEDALVGTSVSQVGATD----ADVGLNGR 615
            T+ + E++++++  ++  P F +Q Y   + ED LV  SV  V A       D    G 
Sbjct: 509 TTSQLSEVAILEILADERPPQFAKQEYEVTVSEDNLVDYSVVDVKAQSFRSFEDGRSKGP 568

Query: 616 IHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673
           I Y L  D  + E   F IDP++G+I   + LD +  A   L  + +      + S V +
Sbjct: 569 ITYSLEGDTPEDETKWFRIDPSTGIIHLTRLLDFDDPALPKLHKLKVTAREDNRESHVDL 628

Query: 674 HIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN 733
            I+I+D+ND+ P F     T  + E+ P+  TI ++ A D D G N+ + YS+    D++
Sbjct: 629 TIRIDDVNDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKDTGDNSRITYSV----DNH 684

Query: 734 SFSLETRQGSDKAELVTMVDLDYESPRK---KYELVIRAASPP--LWNDVRVEILVTDVN 788
           +FS+ +  G   A++   +D D  + R    ++ +  R    P  L +   + I   + N
Sbjct: 685 NFSINS-NGEISAKV--RLDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTN 741

Query: 789 DNAPV-MKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGN-----NANLILL 842
           D + V +   Q      +D     P  ++ A DAD  D++ Y  +  N       NL  +
Sbjct: 742 DESAVFLPTSQYTAFVAEDAQGGTPVIQIQARDAD-RDEVTYSFMDKNGRSTQKMNLFSI 800

Query: 843 NETTGSMTL 851
           +E TG + L
Sbjct: 801 DEHTGLVKL 809


>UniRef50_Q4S488 Cluster: Chromosome undetermined SCAF14743, whole
            genome shotgun sequence; n=2; cellular organisms|Rep:
            Chromosome undetermined SCAF14743, whole genome shotgun
            sequence - Tetraodon nigroviridis (Green puffer)
          Length = 2087

 Score =  258 bits (631), Expect = 2e-66
 Identities = 210/673 (31%), Positives = 312/673 (46%), Gaps = 42/673 (6%)

Query: 40   TTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL 99
            T   TL+   Q++       +T   V    +N              V +  +  G S A 
Sbjct: 566  TGFFTLRVRVQNVASVPLASFTTVYVNVTDVNDNVPFFLSSTYEATVPEGAQT-GTSVAQ 624

Query: 100  LTRASLDR--EKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTV 157
            ++ A LD       RY +L   +           S A +     D         E  Y V
Sbjct: 625  VSAADLDSGPHGTVRYLILRDDSGDWRFFDIDSLSGAIVSRASFDREQKASYLLESLYEV 684

Query: 158  SVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDY 217
            SV+ED  V    VI  + A D D GAN+ +RY I  GN+   F ++   G + + + LDY
Sbjct: 685  SVEEDKEV--GFVIITVTANDEDEGANAKLRYQIAAGNSMGAFDVEPEVGTIFVARPLDY 742

Query: 218  EQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP-IGYSI 276
            E  R Y+L + A DG      N T +++ + + ND AP F  S +  +V+E +  +   I
Sbjct: 743  EAERRYQLRLVASDG---KWENETLVVVEVLNRNDEAPVFSQSQYHAAVTEELSQLPVLI 799

Query: 277  VRVQAYDAD-EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL 335
            ++V A D D E     L Y++  +   G      T+D RSG +Y   +LDRE +  ++ L
Sbjct: 800  LQVSATDPDQEADQGALRYSLHGQGAGGE----FTVDQRSGSIYAHRRLDREERPTWRFL 855

Query: 336  VTATDGGDPPRSATATXXXXXXXXXXXXXXF------MPGQYEVELAEDEPPGTPVVTLT 389
            V ATD G    +  A               F        G +   +AE+ P  T V+ + 
Sbjct: 856  VLATDEGGAGLTGFADVLLEVRDVNDNAPFFPCPALQAEGCFVGRVAENSPADTSVMEMR 915

Query: 390  ATDADEDNR-----LHYEITGGNTRGRFSIT--SQNGR-GLI-TVAQPLDFKQERRYVLT 440
            ATD D+ N      L Y I   N R + ++   S NG  G I TV + LD ++  R+++ 
Sbjct: 916  ATDLDDPNVGANAILTYSIIQ-NVRNQINLNLFSINGATGTIYTVLRSLDREEAERHLVV 974

Query: 441  VSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
            V A D  G + T    I ++D N++APVF    Y+A V ED  +G+ VLVVSA D D G 
Sbjct: 975  VEARDGEGLAGTGTATIIVSDVNDHAPVFTQRLYSAQVTEDLEVGSQVLVVSAMDQDEGQ 1034

Query: 501  NAQITYSL-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG--YLLTVTARDGG 557
            NA +T+S+   +   +     D+   +N + G I   K +D E      + LTV A D  
Sbjct: 1035 NAAVTFSIVGGDEDRKFFLETDR---VN-RRGVIRLQKKVDFEKPQERVFNLTVKAEDSD 1090

Query: 558  VPSLSDTTDVEISVVDVNDNEPVFKQQLY-TANIMEDALVGTSVSQVGATDADVGLNGRI 616
              SLS      + V D ND+ PVF  Q Y  A + ED   GT V+QV A+DAD G NGR+
Sbjct: 1091 FFSLSSCL---VRVEDANDHAPVFSPQFYEAAALSEDTAAGTIVTQVTASDADSGQNGRL 1147

Query: 617  HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676
             Y +  +    G F++D  SG +    +LDRE  + H +  +A D GTP  + T ++ + 
Sbjct: 1148 SYSISRQSDPLGQFLVD-QSGWVLLAGSLDREKTSQHRILLLATDAGTPALTGTAVLIVT 1206

Query: 677  IEDINDSPPVFES 689
            + D+ND+ P FE+
Sbjct: 1207 VLDVNDNGPEFEA 1219



 Score =  209 bits (510), Expect = 1e-51
 Identities = 178/567 (31%), Positives = 260/567 (45%), Gaps = 43/567 (7%)

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            D    A     SL++ SV E+  +G+ I+ V A D DEG NA+L Y +   +  G  D  
Sbjct: 669  DREQKASYLLESLYEVSVEEDKEVGFVIITVTANDEDEGANAKLRYQIAAGNSMGAFD-- 726

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
              ++P  G ++ +  LD E + +YQL + A+DG     +                  F  
Sbjct: 727  --VEPEVGTIFVARPLDYEAERRYQLRLVASDGKWENETLVVVEVLNRNDEAPV---FSQ 781

Query: 369  GQYEVELAEDEPPGTPVVTL--TATDADED---NRLHYEITGGNTRGRFSITSQNGRGLI 423
             QY   + E E    PV+ L  +ATD D++     L Y + G    G F++  ++G   I
Sbjct: 782  SQYHAAVTE-ELSQLPVLILQVSATDPDQEADQGALRYSLHGQGAGGEFTVDQRSGS--I 838

Query: 424  TVAQPLDFKQERRYVLTVSATDSGGRSDT--AMVQINITDANNYAPVFE------NAPYT 475
               + LD ++   +   V ATD GG   T  A V + + D N+ AP F          + 
Sbjct: 839  YAHRRLDREERPTWRFLVLATDEGGAGLTGFADVLLEVRDVNDNAPFFPCPALQAEGCFV 898

Query: 476  ASVFEDAPIGTTVLVVSATDSD---VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
              V E++P  T+V+ + ATD D   VG NA +TYS+   + N+   +    F IN  TG 
Sbjct: 899  GRVAENSPADTSVMEMRATDLDDPNVGANAILTYSIIQNVRNQINLN---LFSINGATGT 955

Query: 533  I-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
            I T  + LDRE    +L+ V ARDG    L+ T    I V DVND+ PVF Q+LY+A + 
Sbjct: 956  IYTVLRSLDREEAERHLVVVEARDG--EGLAGTGTATIIVSDVNDHAPVFTQRLYSAQVT 1013

Query: 592  EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV-IDPAS--GVIRTNKALDRE 648
            ED  VG+ V  V A D D G N  + + +   D +   F+  D  +  GVIR  K +D E
Sbjct: 1014 EDLEVGSQVLVVSAMDQDEGQNAAVTFSIVGGDEDRKFFLETDRVNRRGVIRLQKKVDFE 1073

Query: 649  SVATH--DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL-TFYISENSPIGTT 705
                   +L   A D      SS ++   ++ED ND  PVF         +SE++  GT 
Sbjct: 1074 KPQERVFNLTVKAEDSDFFSLSSCLV---RVEDANDHAPVFSPQFYEAAALSEDTAAGTI 1130

Query: 706  IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765
            + ++ A D D G N  + YSI    D     L  + G     L   +D +  S  +   L
Sbjct: 1131 VTQVTASDADSGQNGRLSYSISRQSDPLGQFLVDQSG--WVLLAGSLDREKTSQHRILLL 1188

Query: 766  VIRAASPPLWNDVRVEILVTDVNDNAP 792
               A +P L     + + V DVNDN P
Sbjct: 1189 ATDAGTPALTGTAVLIVTVLDVNDNGP 1215



 Score =  205 bits (501), Expect = 1e-50
 Identities = 142/441 (32%), Positives = 230/441 (52%), Gaps = 30/441 (6%)

Query: 371  YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
            YEV + ED+  G  ++T+TA D DE  + +L Y+I  GN+ G F +  + G   I VA+P
Sbjct: 682  YEVSVEEDKEVGFVIITVTANDEDEGANAKLRYQIAAGNSMGAFDVEPEVGT--IFVARP 739

Query: 429  LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED-APIGTT 487
            LD++ ERRY L + A+D    ++T +V + + + N+ APVF  + Y A+V E+ + +   
Sbjct: 740  LDYEAERRYQLRLVASDGKWENETLVV-VEVLNRNDEAPVFSQSQYHAAVTEELSQLPVL 798

Query: 488  VLVVSATDSDVGIN-AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
            +L VSATD D   +   + YSL  + +         +F ++ ++G+I  ++ LDRE    
Sbjct: 799  ILQVSATDPDQEADQGALRYSLHGQGAGG-------EFTVDQRSGSIYAHRRLDREERPT 851

Query: 547  YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK------QQLYTANIMEDALVGTSV 600
            +   V A D G   L+   DV + V DVNDN P F       +  +   + E++   TSV
Sbjct: 852  WRFLVLATDEGGAGLTGFADVLLEVRDVNDNAPFFPCPALQAEGCFVGRVAENSPADTSV 911

Query: 601  SQVGATDAD---VGLNGRIHYELDPKDREE---GSFVIDPASGVIRTN-KALDRESVATH 653
             ++ ATD D   VG N  + Y +    R +     F I+ A+G I T  ++LDRE    H
Sbjct: 912  MEMRATDLDDPNVGANAILTYSIIQNVRNQINLNLFSINGATGTIYTVLRSLDREEAERH 971

Query: 654  DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713
             +   A DG     + T    I + D+ND  PVF     +  ++E+  +G+ +  + A D
Sbjct: 972  LVVVEARDGEGLAGTGTAT--IIVSDVNDHAPVFTQRLYSAQVTEDLEVGSQVLVVSAMD 1029

Query: 714  PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK-YELVIRAASP 772
             DEG NA V +SI GGD+   F LET + + +  +     +D+E P+++ + L ++A   
Sbjct: 1030 QDEGQNAAVTFSIVGGDEDRKFFLETDRVNRRGVIRLQKKVDFEKPQERVFNLTVKAEDS 1089

Query: 773  PLWNDVRVEILVTDVNDNAPV 793
              ++     + V D ND+APV
Sbjct: 1090 DFFSLSSCLVRVEDANDHAPV 1110



 Score =  145 bits (351), Expect = 2e-32
 Identities = 138/483 (28%), Positives = 234/483 (48%), Gaps = 50/483 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASS-GTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            + VL+ ND +PVF   QY A+V E  S     +L + ATD D  + A+     +     +
Sbjct: 767  VEVLNRNDEAPVFSQSQYHAAVTEELSQLPVLILQVSATDPD--QEAD-----QGALRYS 819

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            L+ + A              F +D RSG++     LDRE+   +  LV ATD+       
Sbjct: 820  LHGQGAGGE-----------FTVDQRSGSIYAHRRLDREERPTWRFLVLATDEGGA---G 865

Query: 130  LSSTATIHVNIIDDNDNYPQF------SEKTYTVSVDEDISVTDNPVIAKIKATDAD--- 180
            L+  A + + + D NDN P F      +E  +   V E+ S  D  V+ +++ATD D   
Sbjct: 866  LTGFADVLLEVRDVNDNAPFFPCPALQAEGCFVGRVAEN-SPADTSVM-EMRATDLDDPN 923

Query: 181  VGANSAIRYAIIGG-NTQMQ---FSIDSLSGDV-SLVKTLDYEQVRSYRLVIRAQDGGSP 235
            VGAN+ + Y+II     Q+    FSI+  +G + +++++LD E+   + +V+ A+DG   
Sbjct: 924  VGANAILTYSIIQNVRNQINLNLFSINGATGTIYTVLRSLDREEAERHLVVVEARDGEGL 983

Query: 236  SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295
            + + T  ++++  DVND+AP F   L+   V+E++ +G  ++ V A D DEG NA +T++
Sbjct: 984  AGTGTATIIVS--DVNDHAPVFTQRLYSAQVTEDLEVGSQVLVVSAMDQDEGQNAAVTFS 1041

Query: 296  MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355
            +   D      L      R G +    ++D E   +    +T     D    + ++    
Sbjct: 1042 IVGGDEDRKFFLETDRVNRRGVIRLQKKVDFEKPQERVFNLTVK-AEDSDFFSLSSCLVR 1100

Query: 356  XXXXXXXXXXFMPGQYEVE-LAEDEPPGTPVVTLTATDAD--EDNRLHYEITG-GNTRGR 411
                      F P  YE   L+ED   GT V  +TA+DAD  ++ RL Y I+   +  G+
Sbjct: 1101 VEDANDHAPVFSPQFYEAAALSEDTAAGTIVTQVTASDADSGQNGRLSYSISRQSDPLGQ 1160

Query: 412  FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVF 469
            F +      G + +A  LD ++  ++ + + ATD+G    + TA++ + + D N+  P F
Sbjct: 1161 FLVDQS---GWVLLAGSLDREKTSQHRILLLATDAGTPALTGTAVLIVTVLDVNDNGPEF 1217

Query: 470  ENA 472
            E A
Sbjct: 1218 EAA 1220



 Score =  101 bits (241), Expect = 4e-19
 Identities = 71/231 (30%), Positives = 114/231 (49%), Gaps = 9/231 (3%)

Query: 433 QERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492
           Q  R V  + A+D G RS +  + + IT+ +N  P ++   Y  +V E+      ++ + 
Sbjct: 455 QTSRIVRQIVASDGGNRSSSVELTVFITNVHNQPPQWDQPEYWVTVPENTVRDAKIVTIK 514

Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ----TGAITTNKLLDRETMSGYL 548
           AT S +G + ++TY L  E       +   +F + P     + +I   + LD ET   + 
Sbjct: 515 AT-SPLG-DPRVTYDL--EEGQVPETNMPVRFYVKPNRADGSASILVAENLDFETTGFFT 570

Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
           L V  ++     L+  T V ++V DVNDN P F    Y A + E A  GTSV+QV A D 
Sbjct: 571 LRVRVQNVASVPLASFTTVYVNVTDVNDNVPFFLSSTYEATVPEGAQTGTSVAQVSAADL 630

Query: 609 DVGLNGRIHYELDPKDREEGSFV-IDPASGVIRTNKALDRESVATHDLKAV 658
           D G +G + Y +   D  +  F  ID  SG I +  + DRE  A++ L+++
Sbjct: 631 DSGPHGTVRYLILRDDSGDWRFFDIDSLSGAIVSRASFDREQKASYLLESL 681



 Score = 95.5 bits (227), Expect = 2e-17
 Identities = 125/468 (26%), Positives = 199/468 (42%), Gaps = 57/468 (12%)

Query: 336 VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395
           + A+DGG+  RS++                +   +Y V + E+      +VT+ AT    
Sbjct: 463 IVASDGGN--RSSSVELTVFITNVHNQPPQWDQPEYWVTVPENTVRDAKIVTIKATSPLG 520

Query: 396 DNRLHYEITGG-----NTRGRFSI--TSQNGRGLITVAQPLDFKQERRYVLTVSATD--S 446
           D R+ Y++  G     N   RF +     +G   I VA+ LDF+    + L V   +  S
Sbjct: 521 DPRVTYDLEEGQVPETNMPVRFYVKPNRADGSASILVAENLDFETTGFFTLRVRVQNVAS 580

Query: 447 GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506
              +    V +N+TD N+  P F ++ Y A+V E A  GT+V  VSA D D G +  + Y
Sbjct: 581 VPLASFTTVYVNVTDVNDNVPFFLSSTYEATVPEGAQTGTSVAQVSAADLDSGPHGTVRY 640

Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566
            +  + S +      + F I+  +GAI +    DRE  + YLL          SL     
Sbjct: 641 LILRDDSGDW-----RFFDIDSLSGAIVSRASFDREQKASYLL---------ESL----- 681

Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE 626
            E+SV +  D E  F     TAN  ++        Q+ A       N    ++++P   E
Sbjct: 682 YEVSVEE--DKEVGFVIITVTANDEDEGANAKLRYQIAAG------NSMGAFDVEP---E 730

Query: 627 EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686
            G+  +          + LD E+   + L+ VA DG    ++ T++V +++ + ND  PV
Sbjct: 731 VGTIFV---------ARPLDYEAERRYQLRLVASDGKW--ENETLVV-VEVLNRNDEAPV 778

Query: 687 F-ESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSD 744
           F +S        E S +   I ++ A DPD E     + YS+ G      F+++ R GS 
Sbjct: 779 FSQSQYHAAVTEELSQLPVLILQVSATDPDQEADQGALRYSLHGQGAGGEFTVDQRSGSI 838

Query: 745 KAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP 792
            A     +D +     +   L        L     V + V DVNDNAP
Sbjct: 839 YAH--RRLDREERPTWRFLVLATDEGGAGLTGFADVLLEVRDVNDNAP 884



 Score = 79.4 bits (187), Expect = 1e-12
 Identities = 62/213 (29%), Positives = 110/213 (51%), Gaps = 15/213 (7%)

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           SS+  + V I + ++  PQ+ +  Y V+V E+ +V D  ++  IKAT + +G +  + Y 
Sbjct: 472 SSSVELTVFITNVHNQPPQWDQPEYWVTVPEN-TVRDAKIVT-IKAT-SPLG-DPRVTYD 527

Query: 191 IIGG-----NTQMQFSI--DSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
           +  G     N  ++F +  +   G  S++  + LD+E    + L +R Q+  S   ++ T
Sbjct: 528 LEEGQVPETNMPVRFYVKPNRADGSASILVAENLDFETTGFFTLRVRVQNVASVPLASFT 587

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
            + +N+ DVNDN P F +S ++ +V E    G S+ +V A D D G +  + Y +  +D 
Sbjct: 588 TVYVNVTDVNDNVPFFLSSTYEATVPEGAQTGTSVAQVSAADLDSGPHGTVRYLIL-RDD 646

Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQL 334
           +G+      ID  SG + +    DRE +A Y L
Sbjct: 647 SGDWRF-FDIDSLSGAIVSRASFDREQKASYLL 678



 Score = 72.1 bits (169), Expect = 2e-10
 Identities = 44/120 (36%), Positives = 59/120 (49%), Gaps = 6/120 (5%)

Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
           P   N    A V E+ P GT VL V A D+D+G+N Q+ Y +   +  + V+     F I
Sbjct: 130 PQCHNYSQRAVVLENQPPGTGVLRVQAQDADLGVNGQVKYGI---MHRDGVS---SGFHI 183

Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586
           +P  G ITT    DRE    + L+VTA D     L     + + V D NDNEP F+   Y
Sbjct: 184 DPDAGYITTTVSFDRERQREFTLSVTATDQADEPLIGICQITVLVADQNDNEPKFENSRY 243



 Score = 68.1 bits (159), Expect = 3e-09
 Identities = 60/239 (25%), Positives = 103/239 (43%), Gaps = 10/239 (4%)

Query: 454 MVQINITDANNYAPVFENAPYTAS-VFEDAPIGTTVL--VVSATDSDVGINAQITYSLSS 510
           +V + +TD N+  P F +A Y+   V E  P GT++L  ++    S         Y+L+ 
Sbjct: 9   LVVVQVTDQNDCTPEFLHAIYSRDGVPESVPAGTSLLQGIIKLRRSPPPRLRGPQYTLNI 68

Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570
             +++  +     F ++     I    + D        L V    G  P +     + + 
Sbjct: 69  TATDDNAS--GGPFPLSSSAQVIVG--INDVNNNKPVFLEVRGPRGRAPGVGPQGPLPLL 124

Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630
            + +      + Q+   A ++E+   GT V +V A DAD+G+NG++ Y +  +D     F
Sbjct: 125 HLRLFPQCHNYSQR---AVVLENQPPGTGVLRVQAQDADLGVNGQVKYGIMHRDGVSSGF 181

Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES 689
            IDP +G I T  + DRE      L   A D    P      + + + D ND+ P FE+
Sbjct: 182 HIDPDAGYITTTVSFDRERQREFTLSVTATDQADEPLIGICQITVLVADQNDNEPKFEN 240



 Score = 68.1 bits (159), Expect = 3e-09
 Identities = 64/275 (23%), Positives = 116/275 (42%), Gaps = 21/275 (7%)

Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610
           + A DGG  + S + ++ + + +V++  P + Q  Y   + E+ +    +  + AT + +
Sbjct: 463 IVASDGG--NRSSSVELTVFITNVHNQPPQWDQPEYWVTVPENTVRDAKIVTIKAT-SPL 519

Query: 611 GLNGRIHYELD----PKDREEGSFVIDP----ASGVIRTNKALDRESVATHDLKAVAIDG 662
           G + R+ Y+L+    P+      F + P     S  I   + LD E+     L+    + 
Sbjct: 520 G-DPRVTYDLEEGQVPETNMPVRFYVKPNRADGSASILVAENLDFETTGFFTLRVRVQNV 578

Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
            + P +S   V++ + D+ND+ P F S      + E +  GT++ ++ A D D GP+  V
Sbjct: 579 ASVPLASFTTVYVNVTDVNDNVPFFLSSTYEATVPEGAQTGTSVAQVSAADLDSGPHGTV 638

Query: 723 HYSIKGGD--DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRV 780
            Y I   D  D   F +++  G+    +V+    D E         +   S     +V  
Sbjct: 639 RYLILRDDSGDWRFFDIDSLSGA----IVSRASFDREQKASYLLESLYEVSVEEDKEVGF 694

Query: 781 EILVTDVND---NAPVMKDFQIIFNNYKDCFPVGP 812
            I+    ND    A     +QI   N    F V P
Sbjct: 695 VIITVTANDEDEGANAKLRYQIAAGNSMGAFDVEP 729



 Score = 65.3 bits (152), Expect = 2e-08
 Identities = 35/80 (43%), Positives = 47/80 (58%), Gaps = 3/80 (3%)

Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325
           V EN P G  ++RVQA DAD GVN ++ Y +  +D    V     IDP +G++ T+   D
Sbjct: 141 VLENQPPGTGVLRVQAQDADLGVNGQVKYGIMHRD---GVSSGFHIDPDAGYITTTVSFD 197

Query: 326 RETQAKYQLLVTATDGGDPP 345
           RE Q ++ L VTATD  D P
Sbjct: 198 RERQREFTLSVTATDQADEP 217



 Score = 59.3 bits (137), Expect = 2e-06
 Identities = 45/135 (33%), Positives = 65/135 (48%), Gaps = 19/135 (14%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           +NV D ND+ P F    YEA+V EGA +GT+V  + A D D G +  V Y I       L
Sbjct: 591 VNVTDVNDNVPFFLSSTYEATVPEGAQTGTSVAQVSAADLDSGPHGTVRYLI-------L 643

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             +                F ID  SGA+++RAS DRE+ A Y  L+++  + S   D+ 
Sbjct: 644 RDDSGDWR----------FFDIDSLSGAIVSRASFDREQKASY--LLESLYEVSVEEDKE 691

Query: 131 SSTATIHVNIIDDND 145
                I V   D+++
Sbjct: 692 VGFVIITVTANDEDE 706



 Score = 55.6 bits (128), Expect = 2e-05
 Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 2/102 (1%)

Query: 171 IAKIKATDADVGANSAIRYAIIGGN-TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA 229
           + +++A DAD+G N  ++Y I+  +     F ID  +G ++   + D E+ R + L + A
Sbjct: 151 VLRVQAQDADLGVNGQVKYGIMHRDGVSSGFHIDPDAGYITTTVSFDRERQREFTLSVTA 210

Query: 230 QDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271
            D          Q+ + + D NDN P+F  S +Q S  E  P
Sbjct: 211 TDQADEPLIGICQITVLVADQNDNEPKFENSRYQ-STQEATP 251



 Score = 54.8 bits (126), Expect = 3e-05
 Identities = 33/103 (32%), Positives = 52/103 (50%), Gaps = 5/103 (4%)

Query: 696 ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755
           + E+  +G  I  + A+D DEG NA + Y I  G+   +F +E   G+    +     LD
Sbjct: 686 VEEDKEVGFVIITVTANDEDEGANAKLRYQIAAGNSMGAFDVEPEVGT----IFVARPLD 741

Query: 756 YESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQ 798
           YE+ R+ Y+L + A+     N+  V + V + ND APV    Q
Sbjct: 742 YEAERR-YQLRLVASDGKWENETLVVVEVLNRNDEAPVFSQSQ 783



 Score = 54.0 bits (124), Expect = 6e-05
 Identities = 42/126 (33%), Positives = 55/126 (43%), Gaps = 21/126 (16%)

Query: 30  ASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDV 89
           A V E    GT VL ++A D D+G N +V+Y I                       V   
Sbjct: 139 AVVLENQPPGTGVLRVQAQDADLGVNGQVKYGI------------------MHRDGVSSG 180

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F ID  +G + T  S DRE+   +T+ V ATDQA    + L     I V + D NDN P+
Sbjct: 181 FHIDPDAGYITTTVSFDRERQREFTLSVTATDQA---DEPLIGICQITVLVADQNDNEPK 237

Query: 150 FSEKTY 155
           F    Y
Sbjct: 238 FENSRY 243



 Score = 47.2 bits (107), Expect = 0.007
 Identities = 62/239 (25%), Positives = 97/239 (40%), Gaps = 25/239 (10%)

Query: 567 VEISVVDVNDNEPVFKQQLYTAN-IMEDALVGTSVSQVGATDADVGLNGRIH---YELDP 622
           V + V D ND  P F   +Y+ + + E    GTS+ Q G          R+    Y L+ 
Sbjct: 10  VVVQVTDQNDCTPEFLHAIYSRDGVPESVPAGTSLLQ-GIIKLRRSPPPRLRGPQYTLNI 68

Query: 623 KDREE----GSFVIDPASGVI-RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
              ++    G F +  ++ VI   N   + + V            G  PQ    ++H+++
Sbjct: 69  TATDDNASGGPFPLSSSAQVIVGINDVNNNKPVFLEVRGPRGRAPGVGPQGPLPLLHLRL 128

Query: 678 EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD-SNSFS 736
                  P   +      + EN P GT +  ++A D D G N  V Y I   D  S+ F 
Sbjct: 129 F------PQCHNYSQRAVVLENQPPGTGVLRVQAQDADLGVNGQVKYGIMHRDGVSSGFH 182

Query: 737 LETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792
           ++     D   + T V  D E  R ++ L + A   A  PL    ++ +LV D NDN P
Sbjct: 183 ID----PDAGYITTTVSFDRERQR-EFTLSVTATDQADEPLIGICQITVLVADQNDNEP 236



 Score = 47.2 bits (107), Expect = 0.007
 Identities = 35/107 (32%), Positives = 55/107 (51%), Gaps = 9/107 (8%)

Query: 377 EDEPPGTPVVTLTATDAD--EDNRLHYEI--TGGNTRGRFSITSQNGRGLITVAQPLDFK 432
           E++PPGT V+ + A DAD   + ++ Y I    G + G F I      G IT     D +
Sbjct: 143 ENQPPGTGVLRVQAQDADLGVNGQVKYGIMHRDGVSSG-FHIDPD--AGYITTTVSFDRE 199

Query: 433 QERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYAPVFENAPYTAS 477
           ++R + L+V+ATD        + QI   + D N+  P FEN+ Y ++
Sbjct: 200 RQREFTLSVTATDQADEPLIGICQITVLVADQNDNEPKFENSRYQST 246



 Score = 42.7 bits (96), Expect = 0.14
 Identities = 26/88 (29%), Positives = 36/88 (40%), Gaps = 4/88 (4%)

Query: 1280 DFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAP---CYNGAECSDLWDTYI 1336
            D  GCI +  +D +  DL S      + AGC      C S     C     C   W ++ 
Sbjct: 1477 DQSGCIRNLVVDSQVYDLASPGESVDSWAGCRLTDGACVSGAGPSCGPRGSCVADWGSFS 1536

Query: 1337 CDCKEGHTGKDCADSTGPPWRFGGDGML 1364
            C C  G+ G  C D+  P + FG   +L
Sbjct: 1537 CHCGPGYAGLKC-DAAVPEFSFGSGSLL 1563



 Score = 41.1 bits (92), Expect = 0.43
 Identities = 41/173 (23%), Positives = 73/173 (42%), Gaps = 9/173 (5%)

Query: 227 IRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE 286
           I A DGG+  RS++ +L + I +V++  P++    +  +V EN      IV ++A  +  
Sbjct: 463 IVASDGGN--RSSSVELTVFITNVHNQPPQWDQPEYWVTVPENTVRDAKIVTIKA-TSPL 519

Query: 287 GVNAELTYTMTDKDYTG-NVDLPITIDPR----SGWVYTSGQLDRETQAKYQLLVTATDG 341
           G +  +TY + +      N+ +   + P     S  +  +  LD ET   + L V   + 
Sbjct: 520 G-DPRVTYDLEEGQVPETNMPVRFYVKPNRADGSASILVAENLDFETTGFFTLRVRVQNV 578

Query: 342 GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394
              P ++  T              F+   YE  + E    GT V  ++A D D
Sbjct: 579 ASVPLASFTTVYVNVTDVNDNVPFFLSSTYEATVPEGAQTGTSVAQVSAADLD 631


>UniRef50_Q5F4W0 Cluster: Putative uncharacterized protein; n=3;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 2779

 Score =  256 bits (626), Expect = 8e-66
 Identities = 229/834 (27%), Positives = 382/834 (45%), Gaps = 78/834 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I ++D ND++PVF   +Y ASV    S G+ ++T++ATD DIG+N+ + Y I+  +A   
Sbjct: 221 IEIIDANDNAPVFSRSRYTASVSANISIGSHLITVQATDADIGENSRISYDIKKTSA--- 277

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            P ++              F I  +SG + T ASL     + + V+V A+D  SP    L
Sbjct: 278 -PSNSN-------------FAIS-QSGVITTTASL--LPASTHDVIVVASDHGSP---SL 317

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           SS+A + + ++    + P   +  + V       + +N  +  I A  +        +  
Sbjct: 318 SSSAVVTITVLGSTLSSPPL-DIIWLVE-SNSAHLMENSTLGSIVARVSIAQQYRDTKLR 375

Query: 191 IIGGNTQMQFSIDSLSGDVSLV-KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
           +IG +       D     + L+   LD E    + L    +  G     +    L+ I D
Sbjct: 376 LIGSSALCPQQTDQAHVYLLLLCGILDRETASEHHLKFLLEKDGQIIIEHPQ--LLTIGD 433

Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
           +NDNAP++++S  Q  +S N   G S   + A D D G N  + Y++ D +        +
Sbjct: 434 INDNAPQWHSS--QIHISLNRTQGGSRT-LTAKDPDLGQNGWIRYSVLDTEL-------V 483

Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
           +ID  +G ++    +D    ++ +  V A DGG P  S                  F   
Sbjct: 484 SIDKETGRIFVPNTIDCNIGSEIKFRVRAEDGGSPALSTDLQVVADLLDTESKPPQFEKA 543

Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
            ++VE+ ED P GT +V + A ++   N  R+ Y +   +      +T     G + + +
Sbjct: 544 LWQVEIPEDTPIGTCLVKVVANNSQCGNSKRIRYSLQNQDEH----LTVDTMSGTVCIQK 599

Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
             DF++++ Y  TV AT++   + T+++ I + D N+  P+F    Y  +V E       
Sbjct: 600 TFDFEKQKSYQTTVIATNANSETSTSLISIRLKDVNDNWPIFYPNEYHLTVREGPKPEEP 659

Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
           +LVVSA+D D G   +++Y + SE S+         F INP TG +   K L R     +
Sbjct: 660 LLVVSASDMDSGTFGEVSYHILSESSS---------FSINPVTGEVFAQKPLAR---GRF 707

Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
            L V+A+DGG  S  ++ ++ I+V+D +   P F +  Y     ED L G ++  VGA  
Sbjct: 708 HLVVSAKDGGGQSSENSANIHITVIDKDTKTPQFSRSKYEIRTTEDILPGIAIGSVGAM- 766

Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP- 666
                  ++ Y +   D++  +F ID  +G I   + LD +    HD   + I    P  
Sbjct: 767 ------SKVKYSIYSGDQDH-NFSIDEDTGKIYVTRYLDAD---VHDTVLLNIQATLPSG 816

Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
           +S+   V I IED ND+PP F S  +   I E+  +      ++A D D+  N  V YSI
Sbjct: 817 ESNQTQVVIFIEDHNDNPPQFSSSLVEISIREDLKLHEPFYVVQASDKDKKKNGEVRYSI 876

Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEIL 783
                 +S  ++   G    +L T   LDYE+ R  Y+L ++A     PP  +++ + I 
Sbjct: 877 ISSHPGSSIEIDQFTG----QLSTGSLLDYEATR-NYKLRVKATDLGIPPRSSNMTLFIH 931

Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGN 835
           V DVNDNAP  +         ++  P    G+V A D D  +  ++ YRI +G+
Sbjct: 932 VLDVNDNAPEFEKSWYTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRITNGS 985



 Score =  237 bits (581), Expect = 2e-60
 Identities = 209/762 (27%), Positives = 335/762 (43%), Gaps = 67/762 (8%)

Query: 138  VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQ 197
            + I D NDN PQ+      +S++     +       + A D D+G N  IRY+++  +T+
Sbjct: 429  LTIGDINDNAPQWHSSQIHISLNRTQGGSRT-----LTAKDPDLGQNGWIRYSVL--DTE 481

Query: 198  MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF 257
            +  SID  +G + +  T+D       +  +RA+DGGSP+ S   Q++ ++ D     P+F
Sbjct: 482  L-VSIDKETGRIFVPNTIDCNIGSEIKFRVRAEDGGSPALSTDLQVVADLLDTESKPPQF 540

Query: 258  YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317
              +L+Q  + E+ PIG  +V+V A ++  G +  + Y++       N D  +T+D  SG 
Sbjct: 541  EKALWQVEIPEDTPIGTCLVKVVANNSQCGNSKRIRYSLQ------NQDEHLTVDTMSGT 594

Query: 318  VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377
            V      D E Q  YQ  V AT+      ++T+               F P +Y + + E
Sbjct: 595  VCIQKTFDFEKQKSYQTTVIATNANS--ETSTSLISIRLKDVNDNWPIFYPNEYHLTVRE 652

Query: 378  DEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435
               P  P++ ++A+D D      + Y I   ++   FSI    G   +   +PL      
Sbjct: 653  GPKPEEPLLVVSASDMDSGTFGEVSYHILSESSS--FSINPVTGE--VFAQKPL---ARG 705

Query: 436  RYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
            R+ L VSA D GG+S  ++A + I + D +   P F  + Y     ED   G  +     
Sbjct: 706  RFHLVVSAKDGGGQSSENSANIHITVIDKDTKTPQFSRSKYEIRTTEDILPGIAI----- 760

Query: 494  TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553
                VG  +++ YS+ S          D  F I+  TG I   + LD +     LL + A
Sbjct: 761  --GSVGAMSKVKYSIYS-------GDQDHNFSIDEDTGKIYVTRYLDADVHDTVLLNIQA 811

Query: 554  RDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612
                +PS  S+ T V I + D NDN P F   L   +I ED  +      V A+D D   
Sbjct: 812  T---LPSGESNQTQVVIFIEDHNDNPPQFSSSLVEISIREDLKLHEPFYVVQASDKDKKK 868

Query: 613  NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672
            NG + Y +        S  ID  +G + T   LD E+   + L+  A D G PP+SS + 
Sbjct: 869  NGEVRYSII-SSHPGSSIEIDQFTGQLSTGSLLDYEATRNYKLRVKATDLGIPPRSSNMT 927

Query: 673  VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD-- 730
            + I + D+ND+ P FE    T  + ENSP  T +G++ A D D   N  + Y I  G   
Sbjct: 928  LFIHVLDVNDNAPEFEKSWYTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRITNGSEY 987

Query: 731  ---DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDV 787
               D    ++ T++  D+ E+++ VD+   +  K          PP  +     I V DV
Sbjct: 988  FGIDEKLGNVYTKRSIDR-EVISHVDISIVAEDK--------GVPPRSSTASARISVLDV 1038

Query: 788  NDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNET 845
            NDN P       I             G + A D D  +   + YR       + + + ++
Sbjct: 1039 NDNPPSCLSITPIVVPAGSPLSTA-IGTIVAMDPDKGLNGSVLYR---AQLQSSLFVVKS 1094

Query: 846  TGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRL 886
             G + L  QLN +  +   + V V+D GV     +  + VR+
Sbjct: 1095 NGDVYLRRQLNASDERHQRLSVIVSDQGVPRKSVVCHVPVRI 1136



 Score =  207 bits (505), Expect = 4e-51
 Identities = 200/793 (25%), Positives = 337/793 (42%), Gaps = 63/793 (7%)

Query: 91  RIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQF 150
           ++D RSG + T A LD EK +++ ++    +++    D L       V + D+NDN P F
Sbjct: 70  KVDERSGEISTIAHLDYEKRSKFDIVAVKVEESGETIDIL-------VEVDDENDNAPSF 122

Query: 151 SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS------ 204
           +++   + + E   +  +  +  +  TD D       R+ I+ GN    F + S      
Sbjct: 123 ADQVVKLEISEFAQLGTSFALPTV--TDGDGPKFDVHRFVILQGNVNNVFKLASRKVNEQ 180

Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
           L  D+ +   LD E    Y L+I AQDGG P++    +  I I D NDNAP F  S +  
Sbjct: 181 LQADLVVNGQLDREFRDKYELLIEAQDGGKPAKIGQLRCSIEIIDANDNAPVFSRSRYTA 240

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
           SVS N+ IG  ++ VQA DAD G N+ ++Y +       N +  I+   +SG + T+  L
Sbjct: 241 SVSANISIGSHLITVQATDADIGENSRISYDIKKTSAPSNSNFAIS---QSGVITTTASL 297

Query: 325 DRETQAKYQLLVTATDGGDPPRSATA----TXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380
                + + ++V A+D G P  S++A    T              ++       L E+  
Sbjct: 298 --LPASTHDVIVVASDHGSPSLSSSAVVTITVLGSTLSSPPLDIIWLVESNSAHLMENST 355

Query: 381 PGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440
            G+ V  ++      D +L      G++      T Q    L+ +   LD +    + L 
Sbjct: 356 LGSIVARVSIAQQYRDTKLRLI---GSSALCPQQTDQAHVYLLLLCGILDRETASEHHLK 412

Query: 441 VSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
                 G         + I D N+ AP + ++    S+        T   ++A D D+G 
Sbjct: 413 FLLEKDGQIIIEHPQLLTIGDINDNAPQWHSSQIHISLNRTQGGSRT---LTAKDPDLGQ 469

Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560
           N  I YS+   +  E V+       I+ +TG I     +D    S     V A DGG P+
Sbjct: 470 NGWIRYSV---LDTELVS-------IDKETGRIFVPNTIDCNIGSEIKFRVRAEDGGSPA 519

Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620
           LS    V   ++D     P F++ L+   I ED  +GT + +V A ++  G + RI Y L
Sbjct: 520 LSTDLQVVADLLDTESKPPQFEKALWQVEIPEDTPIGTCLVKVVANNSQCGNSKRIRYSL 579

Query: 621 DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680
             +D       +D  SG +   K  D E   ++    +A +  +  ++ST ++ I+++D+
Sbjct: 580 QNQDEH---LTVDTMSGTVCIQKTFDFEKQKSYQTTVIATNANS--ETSTSLISIRLKDV 634

Query: 681 NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR 740
           ND+ P+F  +     + E       +  + A D D G    V Y I    +S+SFS+   
Sbjct: 635 NDNWPIFYPNEYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHIL--SESSSFSINPV 692

Query: 741 QGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDF 797
            G    E+     L     R ++ LV+ A         N   + I V D +   P     
Sbjct: 693 TG----EVFAQKPL----ARGRFHLVVSAKDGGGQSSENSANIHITVIDKDTKTPQFSRS 744

Query: 798 QIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNT 857
           +      +D  P    G V A       K++Y I SG+  +   ++E TG + ++  L+ 
Sbjct: 745 KYEIRTTEDILPGIAIGSVGA-----MSKVKYSIYSGDQDHNFSIDEDTGKIYVTRYLDA 799

Query: 858 NVPKLATMEVSVT 870
           +V     + +  T
Sbjct: 800 DVHDTVLLNIQAT 812



 Score =  192 bits (468), Expect = 1e-46
 Identities = 182/686 (26%), Positives = 298/686 (43%), Gaps = 57/686 (8%)

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            L PE A          +   F +D   G + T   LDRE + RY++ V  T     +  R
Sbjct: 1854 LQPELAGLTYSIVEGNIDSAFSVDSE-GVIRTNLELDREILERYSLKVIGTGSGQQIGTR 1912

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            +     + VN +  NDN P F   +    V E++ V     +A + A D D  A   +RY
Sbjct: 1913 VD----VRVNNL--NDNVPSFP-MSKPRRVPENLRV--GSYVATVGAKDVDNLA--PLRY 1961

Query: 190  AIIG---GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
             ++    G T   F+ID  +G + L   LD+E +  + L I+A DG   S    T L I 
Sbjct: 1962 FLVSDSSGQTPTHFNIDQFTGTIHLTAPLDFEVLPEHTLTIKATDG---SFDTFTNLTIF 2018

Query: 247  IRDVNDNAPRFYTSLFQESVSE-NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
            + D+NDNAP F   L+Q +VS      G    +++A+D D      LTY++      G+ 
Sbjct: 2019 VSDINDNAPTFSKPLYQTTVSPATFSPGQPFAKIEAHDLD--ARGALTYSLGQ----GSS 2072

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX- 364
             +   + P SG ++   ++      +Y + VTATD G P  S +                
Sbjct: 2073 SI-FRVAPESGALFM--KVLPPAGERYLVTVTATDNGVPSFSTSVPVSVIIGEAEPTDKP 2129

Query: 365  XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLIT 424
             F   ++  E+ E+   G  +  L+    +E    HY I        FSI      G + 
Sbjct: 2130 GFEKAEFRFEVMENSKIGLQIGNLSG---EESREFHYRIQDPEASKIFSIDKF---GRLF 2183

Query: 425  VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDA 482
            VA P+D +Q   +   V   +    S     + ++   D N+  PVF +  Y  S+ +  
Sbjct: 2184 VAGPIDREQRATHEFQVEIDNEMMTSQKVQCKCHVIVLDENDNLPVFTSVAYYLSLKDSM 2243

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL---- 538
              G  +  + A+D D G N +++Y + S      V        +NP TG+I  N+     
Sbjct: 2244 AHGQKIGQIMASDQDSGENGRVSYRILSGNDLNIVT-------LNPDTGSIQLNEWNDAQ 2296

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV--DVNDNEPVFKQQLYTANIMEDALV 596
            LD    + + + V ARD G P+ +    V++S+     + + P F   +Y  +++ED  V
Sbjct: 2297 LDEFPNATWQILVEARDHGHPARAAVGKVQVSLKMSSWSGSAPFFVLPVYEVHVLEDTSV 2356

Query: 597  GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
            GT + ++ A++     N  + Y L      +G   ID  +G +     LD ES     + 
Sbjct: 2357 GTVLQKIRASNRLGMRNDGLLYSLK---EHQGKLGIDVKTGELTLKTHLDWESEPIISMY 2413

Query: 657  AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
                DG    +S+ V + I +E +++  PVF     T  I  ++P G ++G+++A D D 
Sbjct: 2414 LSVSDGNG--RSAVVPLKIVVEPVDEFAPVFTKSSYTLQIPISTPAGESVGQMQAIDEDG 2471

Query: 717  GPNAVVHYSIKGGDDSNSFSLETRQG 742
            G + VV YSI   D  ++  +E   G
Sbjct: 2472 GVHGVVKYSI--SDRQSTVKIEEHTG 2495



 Score =  175 bits (425), Expect = 2e-41
 Identities = 169/582 (29%), Positives = 258/582 (44%), Gaps = 69/582 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I + D ND+ P+F   +Y  +VREG      +L + A+D D G   EV Y I       L
Sbjct: 629  IRLKDVNDNWPIFYPNEYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHI-------L 681

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +   +              F I+  +G +  +  L R    R+ ++V A D     S+  
Sbjct: 682  SESSS--------------FSINPVTGEVFAQKPLAR---GRFHLVVSAKDGGGQSSE-- 722

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             ++A IH+ +ID +   PQFS   Y +   EDI     P IA        VGA S ++Y+
Sbjct: 723  -NSANIHITVIDKDTKTPQFSRSKYEIRTTEDIL----PGIA-----IGSVGAMSKVKYS 772

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLINIRD 249
            I  G+    FSID  +G + + + LD +   +  L I+A     PS  SN TQ++I I D
Sbjct: 773  IYSGDQDHNFSIDEDTGKIYVTRYLDADVHDTVLLNIQAT---LPSGESNQTQVVIFIED 829

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
             NDN P+F +SL + S+ E++ +      VQA D D+  N E+ Y++    + G+    I
Sbjct: 830  HNDNPPQFSSSLVEISIREDLKLHEPFYVVQASDKDKKKNGEVRYSII-SSHPGS---SI 885

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             ID  +G + T   LD E    Y+L V ATD G PPRS+  T              F   
Sbjct: 886  EIDQFTGQLSTGSLLDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKS 945

Query: 370  QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
             Y +E+ E+ PP T V  + A D D  E+ ++ Y IT G+    F I  + G   +   +
Sbjct: 946  WYTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRITNGSE--YFGIDEKLGN--VYTKR 1001

Query: 428  PLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAP-VFENAPYTASVFEDAPI 484
             +D +      +++ A D G   RS TA  +I++ D N+  P      P    V   +P+
Sbjct: 1002 SIDREVISHVDISIVAEDKGVPPRSSTASARISVLDVNDNPPSCLSITPIV--VPAGSPL 1059

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
             T +  + A D D G+N  + Y    + S          FV+    G +   + L+    
Sbjct: 1060 STAIGTIVAMDPDKGLNGSVLYRAQLQSS---------LFVVK-SNGDVYLRRQLNASDE 1109

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISV----VDVNDNEPVFK 582
                L+V   D GVP  S    V + +     D+   EP  K
Sbjct: 1110 RHQRLSVIVSDQGVPRKSVVCHVPVRISKGSADIQIQEPFQK 1151



 Score =  172 bits (419), Expect = 1e-40
 Identities = 180/691 (26%), Positives = 296/691 (42%), Gaps = 63/691 (9%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            F I+  +G++     LDRE    + +++  TD  S      + + T+ V + D NDN PQ
Sbjct: 1673 FSINSTTGSISV-LPLDREASQEHLLIIILTDGGSR-----NDSCTVRVTVADQNDNKPQ 1726

Query: 150  FSEKTYT-VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
                T + + + E   V D  V+ + +A+D D+G N    + ++  ++     +   +GD
Sbjct: 1727 LDASTPSELEIAESSRVGD--VLHRFRASDMDIGQNGKFSFELLEDSSG-SLDLVPETGD 1783

Query: 209  VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP---RFYTSLFQES 265
            + L +      ++S+++ +R  D G P       L I+ R+    A     F    +  +
Sbjct: 1784 LVLRRL---SSLQSWKIKLRVVDHGVPGLYVEKNLEISNRNPQTEAKAPLEFLKQTYLST 1840

Query: 266  VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325
            + E +P G  I ++Q   A       LTY++ +    GN+D   ++D   G + T+ +LD
Sbjct: 1841 IDEGLPRGQFIAKLQPELAG------LTYSIVE----GNIDSAFSVDSE-GVIRTNLELD 1889

Query: 326  RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
            RE   +Y L V  T  G        T                P      + E+   G+ V
Sbjct: 1890 REILERYSLKVIGTGSGQQ----IGTRVDVRVNNLNDNVPSFPMSKPRRVPENLRVGSYV 1945

Query: 386  VTLTATDADEDNRLHYEI---TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
             T+ A D D    L Y +   + G T   F+I    G   I +  PLDF+    + LT+ 
Sbjct: 1946 ATVGAKDVDNLAPLRYFLVSDSSGQTPTHFNIDQFTGT--IHLTAPLDFEVLPEHTLTIK 2003

Query: 443  ATDSGGRSDT-AMVQINITDANNYAPVFENAPY--TASVFEDAPIGTTVLVVSATDSDVG 499
            ATD  G  DT   + I ++D N+ AP F    Y  T S    +P G     + A D D  
Sbjct: 2004 ATD--GSFDTFTNLTIFVSDINDNAPTFSKPLYQTTVSPATFSP-GQPFAKIEAHDLDA- 2059

Query: 500  INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
                +TYSL    S+         F + P++GA+    L        YL+TVTA D GVP
Sbjct: 2060 -RGALTYSLGQGSSSI--------FRVAPESGALFMKVL--PPAGERYLVTVTATDNGVP 2108

Query: 560  SLSDTTDVEISVVDVNDNE-PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618
            S S +  V + + +    + P F++  +   +ME++ +G  +  +   ++        HY
Sbjct: 2109 SFSTSVPVSVIIGEAEPTDKPGFEKAEFRFEVMENSKIGLQIGNLSGEESR-----EFHY 2163

Query: 619  ELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678
             +   +  +  F ID   G +     +DRE  ATH+ +    +     Q      H+ + 
Sbjct: 2164 RIQDPEASK-IFSIDKF-GRLFVAGPIDREQRATHEFQVEIDNEMMTSQKVQCKCHVIVL 2221

Query: 679  DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738
            D ND+ PVF S      + ++   G  IG+I A D D G N  V Y I  G+D N  +L 
Sbjct: 2222 DENDNLPVFTSVAYYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRILSGNDLNIVTLN 2281

Query: 739  TRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
               GS +        LD E P   +++++ A
Sbjct: 2282 PDTGSIQLNEWNDAQLD-EFPNATWQILVEA 2311



 Score =  168 bits (409), Expect = 2e-39
 Identities = 185/748 (24%), Positives = 318/748 (42%), Gaps = 69/748 (9%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            F ID  +G +     LD +     TVL+    QA+  S   + T  + + I D NDN PQ
Sbjct: 782  FSIDEDTGKIYVTRYLDAD--VHDTVLLNI--QATLPSGESNQTQVV-IFIEDHNDNPPQ 836

Query: 150  FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209
            FS     +S+ ED+ + +   +  ++A+D D   N  +RY+II  +      ID  +G +
Sbjct: 837  FSSSLVEISIREDLKLHEPFYV--VQASDKDKKKNGEVRYSIISSHPGSSIEIDQFTGQL 894

Query: 210  SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269
            S    LDYE  R+Y+L ++A D G P RS+   L I++ DVNDNAP F  S +   V EN
Sbjct: 895  STGSLLDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLEN 954

Query: 270  VPIGYSIVRVQAYDADEGVNAELTYTMTD-KDYTGNVDLPITIDPRSGWVYTSGQLDRET 328
             P    + +V A D D   N ++ Y +T+  +Y G       ID + G VYT   +DRE 
Sbjct: 955  SPPKTIVGKVVARDKDSLENGQIVYRITNGSEYFG-------IDEKLGNVYTKRSIDREV 1007

Query: 329  QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388
             +   + + A D G PPRS+TA+               +     + +    P  T + T+
Sbjct: 1008 ISHVDISIVAEDKGVPPRSSTASARISVLDVNDNPPSCL-SITPIVVPAGSPLSTAIGTI 1066

Query: 389  TATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG 448
             A D D+   L+  +     + + S+      G + + + L+   ER   L+V  +D G 
Sbjct: 1067 VAMDPDKG--LNGSVL-YRAQLQSSLFVVKSNGDVYLRRQLNASDERHQRLSVIVSDQGV 1123

Query: 449  RSDTAMVQINITDANNYAPVFENAPYT--ASVFEDAPIGTTVLVVSATDSDVGINAQITY 506
               + +  + +  +   A +    P+     + +  P G  +  ++AT    G+++ +  
Sbjct: 1124 PRKSVVCHVPVRISKGSADIQIQEPFQKYIEIPKSCPTGCRLTTLNAT----GVSSWLIQ 1179

Query: 507  SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566
              SSEISN         F+I+           + R     Y L +   D       +   
Sbjct: 1180 --SSEISNHFAIREGVLFMISHP---------IHRPP---YSLVIVLSD------KNDRQ 1219

Query: 567  VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE 626
              I +  +   E   K++  T  I +   +GT + ++G   AD    G   Y       E
Sbjct: 1220 KSIQLRVLASGEAANKEE--TIRISDSNSIGTKIGRLGEKSAD----GSFFYRF--SSEE 1271

Query: 627  EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI-VHIKIEDINDSPP 685
                 +D   G++     L R    TH+         T   S+  + V ++I       P
Sbjct: 1272 SCPLELDQTGGLLYLADGLRRGD--THNFSCFFEKFNTTDGSAEEMRVDLEISRTKSDKP 1329

Query: 686  VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745
             F++  L   I E++P G+ I  + A   D+  + +   S +     ++FS++   G   
Sbjct: 1330 RFDTGHLRVNIREDTPTGSIITTVNATVSDDSASPI---SYRFPLLIDNFSIDQFTGD-- 1384

Query: 746  AELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP--VMKDFQIIFNN 803
               +T++D  +      Y L++ A +      + V + V DVND+ P  V +   ++ ++
Sbjct: 1385 ---ITLIDTLHWHVTPTYNLIVEAFTSGPGTTLLVTVNVDDVNDHTPFIVSQPTVLLPSS 1441

Query: 804  YKDCFPVGPFGRVPAYDADVTDKLQYRI 831
            Y+     G   RV A D D   +++Y +
Sbjct: 1442 YR---KGGMVHRVVAIDLDKDPEIRYSL 1466



 Score =  167 bits (406), Expect = 4e-39
 Identities = 207/771 (26%), Positives = 333/771 (43%), Gaps = 77/771 (9%)

Query: 95   RSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKT 154
            +S  ++ +++       R+T++ +  D+         ST  IHV  +      P+ S  +
Sbjct: 1584 KSSKIVQKSASVATGTQRFTIVAQKDDELD------YSTLKIHVEPVFTEP--PKISSTS 1635

Query: 155  Y-TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVK 213
               V+++E++ + D     +I AT   +   S  R+    GN   +FSI+S +G +S++ 
Sbjct: 1636 CGVVTIEENVGIED---FKRILATG--MTEESRFRFQ---GNAP-KFSINSTTGSISVLP 1686

Query: 214  TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE-SVSENVPI 272
             LD E  + + L+I   DGGS  R+++  + + + D NDN P+   S   E  ++E+  +
Sbjct: 1687 -LDREASQEHLLIIILTDGGS--RNDSCTVRVTVADQNDNKPQLDASTPSELEIAESSRV 1743

Query: 273  GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332
            G  + R +A D D G N + ++ + + D +G++DL     P +G +    +L      K 
Sbjct: 1744 GDVLHRFRASDMDIGQNGKFSFELLE-DSSGSLDLV----PETGDLVLR-RLSSLQSWKI 1797

Query: 333  QLLVTATDGGDPPRSATATXXXXXXXXXXXXXX---FMPGQYEVELAEDEPPGTPVVTLT 389
            +L V   D G P                        F+   Y   + E  P G  +  L 
Sbjct: 1798 KLRVV--DHGVPGLYVEKNLEISNRNPQTEAKAPLEFLKQTYLSTIDEGLPRGQFIAKLQ 1855

Query: 390  ATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR 449
               A     L Y I  GN    FS+ S+   G+I     LD +   RY L V  T SG +
Sbjct: 1856 PELAG----LTYSIVEGNIDSAFSVDSE---GVIRTNLELDREILERYSLKVIGTGSGQQ 1908

Query: 450  SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509
              T  V + + + N+  P F  +     V E+  +G+ V  V A D D    A + Y L 
Sbjct: 1909 IGTR-VDVRVNNLNDNVPSFPMSK-PRRVPENLRVGSYVATVGAKDVDN--LAPLRYFLV 1964

Query: 510  SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569
            S+ S +   H    F I+  TG I     LD E +  + LT+ A DG   S    T++ I
Sbjct: 1965 SDSSGQTPTH----FNIDQFTGTIHLTAPLDFEVLPEHTLTIKATDG---SFDTFTNLTI 2017

Query: 570  SVVDVNDNEPVFKQQLYTANIMEDALV-GTSVSQVGATDADVGLNGRIHYELDPKDREEG 628
             V D+NDN P F + LY   +       G   +++ A D D    G + Y L        
Sbjct: 2018 FVSDINDNAPTFSKPLYQTTVSPATFSPGQPFAKIEAHDLDA--RGALTYSLG--QGSSS 2073

Query: 629  SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP-PVF 687
             F + P SG +   K L       + +   A D G P  S++V V + I +   +  P F
Sbjct: 2074 IFRVAPESGALFM-KVLPPAG-ERYLVTVTATDNGVPSFSTSVPVSVIIGEAEPTDKPGF 2131

Query: 688  ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747
            E     F + ENS IG  IG +   +  E      HY I+  + S  FS++         
Sbjct: 2132 EKAEFRFEVMENSKIGLQIGNLSGEESRE-----FHYRIQDPEASKIFSIDKF-----GR 2181

Query: 748  LVTMVDLDYESPRKKYELVIRAASPPLWND---VRVEILVTDVNDNAPVMKDFQIIFNNY 804
            L     +D E  R  +E  +   +  + +     +  ++V D NDN PV       + + 
Sbjct: 2182 LFVAGPIDREQ-RATHEFQVEIDNEMMTSQKVQCKCHVIVLDENDNLPVFTSVAY-YLSL 2239

Query: 805  KDCFPVGP-FGRVPAYDADVTD--KLQYRILSGNNANLILLNETTGSMTLS 852
            KD    G   G++ A D D  +  ++ YRILSGN+ N++ LN  TGS+ L+
Sbjct: 2240 KDSMAHGQKIGQIMASDQDSGENGRVSYRILSGNDLNIVTLNPDTGSIQLN 2290



 Score =  142 bits (345), Expect = 9e-32
 Identities = 166/683 (24%), Positives = 295/683 (43%), Gaps = 54/683 (7%)

Query: 184 NSAIRYAIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLV-IRAQDGGSPSRSNT 240
           ++A +Y ++  + Q      +D  SG++S +  LDYE+   + +V ++ ++ G      T
Sbjct: 51  SAAPKYFVVFPDEQTSKFLKVDERSGEISTIAHLDYEKRSKFDIVAVKVEESG-----ET 105

Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
             +L+ + D NDNAP F   + +  +SE   +G S       D D G   ++   +  + 
Sbjct: 106 IDILVEVDDENDNAPSFADQVVKLEISEFAQLGTSFALPTVTDGD-GPKFDVHRFVILQG 164

Query: 301 YTGNVDLPIT---IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357
              NV    +    +     +  +GQLDRE + KY+LL+ A DGG P +           
Sbjct: 165 NVNNVFKLASRKVNEQLQADLVVNGQLDREFRDKYELLIEAQDGGKPAKIGQLRCSIEII 224

Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEI--TGGNTRGRFS 413
                   F   +Y   ++ +   G+ ++T+ ATDAD  E++R+ Y+I  T   +   F+
Sbjct: 225 DANDNAPVFSRSRYTASVSANISIGSHLITVQATDADIGENSRISYDIKKTSAPSNSNFA 284

Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAP----VF 469
           I+     G+IT    L        ++  S   S   S +A+V I +  +   +P    ++
Sbjct: 285 ISQS---GVITTTASLLPASTHDVIVVASDHGSPSLSSSAVVTITVLGSTLSSPPLDIIW 341

Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
                +A + E++ +G+ V  VS          ++  S     S       DQ  V    
Sbjct: 342 LVESNSAHLMENSTLGSIVARVSIAQQYRDTKLRLIGS-----SALCPQQTDQAHVY--- 393

Query: 530 TGAITTNKLLDRETMS-GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588
              +    +LDRET S  +L  +  +DG +  + +   + +++ D+NDN P +       
Sbjct: 394 --LLLLCGILDRETASEHHLKFLLEKDGQI--IIEHPQL-LTIGDINDNAPQWHSS--QI 446

Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648
           +I  +   G S   + A D D+G NG I Y +   D E  S  ID  +G I     +D  
Sbjct: 447 HISLNRTQGGS-RTLTAKDPDLGQNGWIRYSV--LDTELVS--IDKETGRIFVPNTIDCN 501

Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
             +    +  A DGG+P  S+ + V   + D    PP FE       I E++PIGT + +
Sbjct: 502 IGSEIKFRVRAEDGGSPALSTDLQVVADLLDTESKPPQFEKALWQVEIPEDTPIGTCLVK 561

Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768
           + A++   G +  + YS++  D+    +++T  G+    +      D+E  +     VI 
Sbjct: 562 VVANNSQCGNSKRIRYSLQNQDE--HLTVDTMSGT----VCIQKTFDFEKQKSYQTTVIA 615

Query: 769 AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDK 826
             +    +   + I + DVNDN P+    +      +   P  P   V A D D     +
Sbjct: 616 TNANSETSTSLISIRLKDVNDNWPIFYPNEYHLTVREGPKPEEPLLVVSASDMDSGTFGE 675

Query: 827 LQYRILSGNNANLILLNETTGSM 849
           + Y ILS +++    +N  TG +
Sbjct: 676 VSYHILSESSS--FSINPVTGEV 696



 Score =  142 bits (343), Expect = 2e-31
 Identities = 155/620 (25%), Positives = 264/620 (42%), Gaps = 54/620 (8%)

Query: 149  QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
            +F ++TY  ++DE +       IAK++   A       + Y+I+ GN    FS+DS  G 
Sbjct: 1831 EFLKQTYLSTIDEGLP--RGQFIAKLQPELA------GLTYSIVEGNIDSAFSVDS-EGV 1881

Query: 209  VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268
            +     LD E +  Y L +     G   +   T++ + + ++NDN P F  S     V E
Sbjct: 1882 IRTNLELDREILERYSLKVIGTGSG---QQIGTRVDVRVNNLNDNVPSFPMSK-PRRVPE 1937

Query: 269  NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328
            N+ +G  +  V A D D    A L Y +   D +G       ID  +G ++ +  LD E 
Sbjct: 1938 NLRVGSYVATVGAKDVDN--LAPLRYFLVS-DSSGQTPTHFNIDQFTGTIHLTAPLDFEV 1994

Query: 329  QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE-PPGTPVVT 387
              ++ L + ATDG                        F    Y+  ++     PG P   
Sbjct: 1995 LPEHTLTIKATDGSF---DTFTNLTIFVSDINDNAPTFSKPLYQTTVSPATFSPGQPFAK 2051

Query: 388  LTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447
            + A D D    L Y +  G++   F +  ++G   + V  P       RY++TV+ATD+G
Sbjct: 2052 IEAHDLDARGALTYSLGQGSS-SIFRVAPESGALFMKVLPPAG----ERYLVTVTATDNG 2106

Query: 448  GRSDTAMVQINITDAN---NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504
              S +  V +++          P FE A +   V E++ IG  +  +S  +S    + +I
Sbjct: 2107 VPSFSTSVPVSVIIGEAEPTDKPGFEKAEFRFEVMENSKIGLQIGNLSGEESRE-FHYRI 2165

Query: 505  TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT 564
                +S+I +  +    + FV  P          +DRE  + +   V   +  + S    
Sbjct: 2166 QDPEASKIFS--IDKFGRLFVAGP----------IDREQRATHEFQVEIDNEMMTSQKVQ 2213

Query: 565  TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624
                + V+D NDN PVF    Y  ++ +    G  + Q+ A+D D G NGR+ Y +    
Sbjct: 2214 CKCHVIVLDENDNLPVFTSVAYYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRI-LSG 2272

Query: 625  REEGSFVIDPASGVIRTNK----ALDRESVATHDLKAVAIDGGTPPQSST--VIVHIKIE 678
             +     ++P +G I+ N+     LD    AT  +   A D G P +++   V V +K+ 
Sbjct: 2273 NDLNIVTLNPDTGSIQLNEWNDAQLDEFPNATWQILVEARDHGHPARAAVGKVQVSLKMS 2332

Query: 679  DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738
              + S P F       ++ E++ +GT + +IRA +     N  + YS+K  +      ++
Sbjct: 2333 SWSGSAPFFVLPVYEVHVLEDTSVGTVLQKIRASNRLGMRNDGLLYSLK--EHQGKLGID 2390

Query: 739  TRQGSDKAELVTMVDLDYES 758
             + G    EL     LD+ES
Sbjct: 2391 VKTG----ELTLKTHLDWES 2406



 Score =  124 bits (298), Expect = 5e-26
 Identities = 123/500 (24%), Positives = 209/500 (41%), Gaps = 38/500 (7%)

Query: 89   VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
            +FR+   SGAL  +      +  RY V V ATD   P S   S   ++ +   +  D  P
Sbjct: 2074 IFRVAPESGALFMKVLPPAGE--RYLVTVTATDNGVP-SFSTSVPVSVIIGEAEPTDK-P 2129

Query: 149  QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
             F +  +   V E+  +     I  +   ++         Y I        FSID   G 
Sbjct: 2130 GFEKAEFRFEVMENSKI--GLQIGNLSGEES-----REFHYRIQDPEASKIFSIDKF-GR 2181

Query: 209  VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268
            + +   +D EQ  ++   +   +    S+    +  + + D NDN P F +  +  S+ +
Sbjct: 2182 LFVAGPIDREQRATHEFQVEIDNEMMTSQKVQCKCHVIVLDENDNLPVFTSVAYYLSLKD 2241

Query: 269  NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV----YTSGQL 324
            ++  G  I ++ A D D G N  ++Y +     +GN    +T++P +G +    +   QL
Sbjct: 2242 SMAHGQKIGQIMASDQDSGENGRVSYRIL----SGNDLNIVTLNPDTGSIQLNEWNDAQL 2297

Query: 325  DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX--FMPGQYEVELAEDEPPG 382
            D    A +Q+LV A D G P R+A                   F+   YEV + ED   G
Sbjct: 2298 DEFPNATWQILVEARDHGHPARAAVGKVQVSLKMSSWSGSAPFFVLPVYEVHVLEDTSVG 2357

Query: 383  TPVVTLTATD--ADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440
            T +  + A++     ++ L Y +     +G+  I  + G   +T+   LD++ E    + 
Sbjct: 2358 TVLQKIRASNRLGMRNDGLLYSLK--EHQGKLGIDVKTGE--LTLKTHLDWESEPIISMY 2413

Query: 441  VSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
            +S +D  GRS    ++I +   + +APVF  + YT  +    P G +V  + A D D G+
Sbjct: 2414 LSVSDGNGRSAVVPLKIVVEPVDEFAPVFTKSSYTLQIPISTPAGESVGQMQAIDEDGGV 2473

Query: 501  NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK-LLDRETMSGYLLTVTARDGGVP 559
            +  + YS+S   S   +  H         TG I   K L+ R  ++   +TV A      
Sbjct: 2474 HGVVKYSISDRQSTVKIEEH---------TGIIRLQKPLVSRRNLTIEQITVVAYSSPTK 2524

Query: 560  SLSDTTDVEISVVDVNDNEP 579
                T  +EI   DV  + P
Sbjct: 2525 QSKTTVYLEIGPFDVQPSLP 2544



 Score = 88.2 bits (209), Expect = 3e-15
 Identities = 79/297 (26%), Positives = 131/297 (44%), Gaps = 28/297 (9%)

Query: 13   VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI---ELVTADT 69
            VLD ND+ PVF    Y  S+++  + G  +  + A+DQD G+N  V Y I     +   T
Sbjct: 2220 VLDENDNLPVFTSVAYYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRILSGNDLNIVT 2279

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            LNP+                             A LD    A + +LV+A D   P    
Sbjct: 2280 LNPDTGSIQLNE------------------WNDAQLDEFPNATWQILVEARDHGHPARAA 2321

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            +     + + +   + + P F    Y V V ED SV    V+ KI+A++     N  + Y
Sbjct: 2322 VGK-VQVSLKMSSWSGSAPFFVLPVYEVHVLEDTSV--GTVLQKIRASNRLGMRNDGLLY 2378

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            ++     Q +  ID  +G+++L   LD+E      + +   DG    RS    L I +  
Sbjct: 2379 SL--KEHQGKLGIDVKTGELTLKTHLDWESEPIISMYLSVSDGN--GRSAVVPLKIVVEP 2434

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            V++ AP F  S +   +  + P G S+ ++QA D D GV+  + Y+++D+  T  ++
Sbjct: 2435 VDEFAPVFTKSSYTLQIPISTPAGESVGQMQAIDEDGGVHGVVKYSISDRQSTVKIE 2491



 Score = 87.8 bits (208), Expect = 4e-15
 Identities = 105/406 (25%), Positives = 182/406 (44%), Gaps = 33/406 (8%)

Query: 478  VFEDAP-IGTTVLVVSATDSDVGIN--AQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
            VF + P I +T   V   + +VGI    +I  +  +E S      +  +F IN  TG+I+
Sbjct: 1624 VFTEPPKISSTSCGVVTIEENVGIEDFKRILATGMTEESRFRFQGNAPKFSINSTTGSIS 1683

Query: 535  TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA-NIMED 593
               L DRE    +LL +   DGG  S +D+  V ++V D NDN+P       +   I E 
Sbjct: 1684 VLPL-DREASQEHLLIIILTDGG--SRNDSCTVRVTVADQNDNKPQLDASTPSELEIAES 1740

Query: 594  ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653
            + VG  + +  A+D D+G NG+  +EL   +   GS  + P +G +   +     S+ + 
Sbjct: 1741 SRVGDVLHRFRASDMDIGQNGKFSFEL--LEDSSGSLDLVPETGDLVLRRL---SSLQSW 1795

Query: 654  DLKAVAIDGGTPP---QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710
             +K   +D G P    + +  I +   +    +P  F        I E  P G  I +++
Sbjct: 1796 KIKLRVVDHGVPGLYVEKNLEISNRNPQTEAKAPLEFLKQTYLSTIDEGLPRGQFIAKLQ 1855

Query: 711  AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770
               P+    A + YSI  G+  ++FS+++     +  + T ++LD E   ++Y L +   
Sbjct: 1856 ---PEL---AGLTYSIVEGNIDSAFSVDS-----EGVIRTNLELDREI-LERYSLKVIGT 1903

Query: 771  SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDKLQY 829
                    RV++ V ++NDN P     +       +   VG +   V A D D    L+Y
Sbjct: 1904 GSGQQIGTRVDVRVNNLNDNVPSFPMSKP--RRVPENLRVGSYVATVGAKDVDNLAPLRY 1961

Query: 830  RILS---GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
             ++S   G       +++ TG++ L+  L+  V    T+ +  TDG
Sbjct: 1962 FLVSDSSGQTPTHFNIDQFTGTIHLTAPLDFEVLPEHTLTIKATDG 2007



 Score = 81.4 bits (192), Expect = 3e-13
 Identities = 66/221 (29%), Positives = 104/221 (47%), Gaps = 14/221 (6%)

Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638
           P F Q L    + E A +GT +  +     +       ++ + P ++      +D  SG 
Sbjct: 20  PTFCQCLTKFTVPESAQIGTRIGWISGKREESAAPK--YFVVFPDEQTSKFLKVDERSGE 77

Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698
           I T   LD E  +  D+ AV ++        T+ + ++++D ND+ P F    +   ISE
Sbjct: 78  ISTIAHLDYEKRSKFDIVAVKVE----ESGETIDILVEVDDENDNAPSFADQVVKLEISE 133

Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVH-YSIKGGDDSNSFSLETRQGSD--KAELVTMVDLD 755
            + +GT+       D D GP   VH + I  G+ +N F L +R+ ++  +A+LV    LD
Sbjct: 134 FAQLGTSFALPTVTDGD-GPKFDVHRFVILQGNVNNVFKLASRKVNEQLQADLVVNGQLD 192

Query: 756 YESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPV 793
            E  R KYEL+I A     P     +R  I + D NDNAPV
Sbjct: 193 REF-RDKYELLIEAQDGGKPAKIGQLRCSIEIIDANDNAPV 232



 Score = 54.8 bits (126), Expect = 3e-05
 Identities = 50/196 (25%), Positives = 90/196 (45%), Gaps = 18/196 (9%)

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS- 185
            +D  +    + + I     + P+F      V++ ED       +I  + AT +D  A+  
Sbjct: 1308 TDGSAEEMRVDLEISRTKSDKPRFDTGHLRVNIREDTPT--GSIITTVNATVSDDSASPI 1365

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
            + R+ ++  N    FSID  +GD++L+ TL +    +Y L++ A   G      T  + +
Sbjct: 1366 SYRFPLLIDN----FSIDQFTGDITLIDTLHWHVTPTYNLIVEAFTSGP---GTTLLVTV 1418

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
            N+ DVND+ P F  S     +  +   G  + RV A D D+  + E+ Y++    Y G+ 
Sbjct: 1419 NVDDVNDHTP-FIVSQPTVLLPSSYRKGGMVHRVVAIDLDK--DPEIRYSL---KYAGSE 1472

Query: 306  DLP--ITIDPRSGWVY 319
                   ID +SG ++
Sbjct: 1473 VAKEFFKIDEKSGEIF 1488



 Score = 44.4 bits (100), Expect = 0.046
 Identities = 53/192 (27%), Positives = 75/192 (39%), Gaps = 14/192 (7%)

Query: 448  GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507
            G ++   V + I+   +  P F+      ++ ED P G+ +  V+AT SD    + I+Y 
Sbjct: 1310 GSAEEMRVDLEISRTKSDKPRFDTGHLRVNIREDTPTGSIITTVNATVSDDSA-SPISYR 1368

Query: 508  LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567
                I N         F I+  TG IT    L       Y L V A   G      T  V
Sbjct: 1369 FPLLIDN---------FSIDQFTGDITLIDTLHWHVTPTYNLIVEAFTSGP---GTTLLV 1416

Query: 568  EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627
             ++V DVND+ P    Q  T  +      G  V +V A D D     R   +    +  +
Sbjct: 1417 TVNVDDVNDHTPFIVSQ-PTVLLPSSYRKGGMVHRVVAIDLDKDPEIRYSLKYAGSEVAK 1475

Query: 628  GSFVIDPASGVI 639
              F ID  SG I
Sbjct: 1476 EFFKIDEKSGEI 1487



 Score = 44.4 bits (100), Expect = 0.046
 Identities = 107/492 (21%), Positives = 186/492 (37%), Gaps = 42/492 (8%)

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQNGRGLIT 424
            F  G   V + ED P G+ + T+ AT +D+  + + Y          FSI    G   IT
Sbjct: 1331 FDTGHLRVNIREDTPTGSIITTVNATVSDDSASPISYRFP--LLIDNFSIDQFTGD--IT 1386

Query: 425  VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
            +   L +     Y L V A  SG  + T +V +N+ D N++ P   + P T  +      
Sbjct: 1387 LIDTLHWHVTPTYNLIVEAFTSGPGT-TLLVTVNVDDVNDHTPFIVSQP-TVLLPSSYRK 1444

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            G  V  V A D D   + +I YSL    S  A     + F I+ ++G I           
Sbjct: 1445 GGMVHRVVAIDLDK--DPEIRYSLKYAGSEVA----KEFFKIDEKSGEIFV-------VE 1491

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
            S   L+ +    G+P        ++  +   D + V    L  +N               
Sbjct: 1492 SSSALSTSFGGAGLPETLTIRATDLQDLTKFDEQKVL---LKASNASRSTWHFFDEQHKD 1548

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE-SVATHDLK-AVAIDG 662
             T       G    +L  ++  +   +       ++++K + +  SVAT   +  +    
Sbjct: 1549 VTILSTSPQGSQILQLKFQEGVDLQLIPSSPHFELKSSKIVQKSASVATGTQRFTIVAQK 1608

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
                  ST+ +H++     + P +  + C    I EN  I      I A     G     
Sbjct: 1609 DDELDYSTLKIHVE-PVFTEPPKISSTSCGVVTIEENVGI-EDFKRILA----TGMTEES 1662

Query: 723  HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEI 782
             +  +G  ++  FS+ +  GS     ++++ LD E+ ++   ++I        +   V +
Sbjct: 1663 RFRFQG--NAPKFSINSTTGS-----ISVLPLDREASQEHLLIIILTDGGSRNDSCTVRV 1715

Query: 783  LVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADV--TDKLQYRILSGNNANL 839
             V D NDN P +           +   VG    R  A D D+    K  + +L  ++ +L
Sbjct: 1716 TVADQNDNKPQLDASTPSELEIAESSRVGDVLHRFRASDMDIGQNGKFSFELLEDSSGSL 1775

Query: 840  ILLNETTGSMTL 851
             L+ E TG + L
Sbjct: 1776 DLVPE-TGDLVL 1786


>UniRef50_UPI0000DB7905 Cluster: PREDICTED: similar to Cad99C
           CG31009-PA, partial; n=3; Endopterygota|Rep: PREDICTED:
           similar to Cad99C CG31009-PA, partial - Apis mellifera
          Length = 1556

 Score =  255 bits (625), Expect = 1e-65
 Identities = 251/898 (27%), Positives = 385/898 (42%), Gaps = 73/898 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVL-TLKATDQDIGKNAEVEYTIELVTADT 69
           + V D ND++P F    YE +V E    G+T+   + A D D G N  VEY+I       
Sbjct: 99  VRVSDINDNAPKFINTPYETTVPELTPVGSTIFKNVVAVDADAGVNGIVEYSIAPGDGTG 158

Query: 70  LNPEDAXXXXXXXXXXVQDVFRID-GRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
           +   D               F I+    G +    +LD E+  RY V + A+D+A  VS+
Sbjct: 159 IGNNDGVGRNRITTADGYGYFSINLPHQGQVTVNRTLDFERTQRYLVTILASDRARNVSE 218

Query: 129 RLSSTATIHVNIIDDNDNYPQF------------SEKTYTVSVDEDI-SVTDNPVIAKIK 175
           R +ST T+ VNI DD+D  P F                Y+ SV   + S   N    KI+
Sbjct: 219 RFTSTTTLTVNIRDDDDQDPSFIYQGCMLLDGACINPEYSASVSSGVLSGILNISPEKIQ 278

Query: 176 ATDADVGANSAIRYAIIGGNT---QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232
           A D D   N+ I Y+ + GN    +  F I+  +G V  +K +D    + + ++I+A + 
Sbjct: 279 AVDMD-SINAPIHYSFLSGNPPNYREFFEINPNTGAVKQIKAVDTTVTKRFDIIIKAVEV 337

Query: 233 GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR-------VQAYDAD 285
               RS T +L I ++ V+ N P    S  +  V EN PIG  ++        +   DAD
Sbjct: 338 SEAKRSATAKLTITVKPVDSNPPIITASSIEGFVDENAPIGTKVIDKDGDPIVLTVSDAD 397

Query: 286 EGV-NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE--TQAKYQLLVTATDGG 342
            G  + +  Y+    + T N      IDP    V     LDR+  +  +++  V A +  
Sbjct: 398 LGPDDPKPAYSF---ELTTNF---FAIDPSGMLVVNEENLDRDPPSPGRFRFQVVAREKT 451

Query: 343 DPPRSATATXXXXXXXXXXXXXXF-MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHY 401
               SA  +                M     V+  E +   T  V  T  D  E+  + Y
Sbjct: 452 GVAASAPLSFVVILNDVNDNAPMLPMIPPITVQAGETKKVVTK-VEATDNDEGENAEITY 510

Query: 402 EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN-IT 460
            I   +  G          G+I   + L+  ++  + +TV ATD GG+    +V++N I 
Sbjct: 511 SIYHVSNNGLHKFKIDPRTGVIESVRKLNAGEQ--FSITVQATDKGGKYSQTIVEVNVIP 568

Query: 461 DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520
             N  +PVF+   Y   V E A I +T+ +V A D +   N  ++YS+ S   N+     
Sbjct: 569 GPNTRSPVFQQPVYEVQVSEGASINSTMTIVHAVDPE---NDPVSYSIVS--GNDL---- 619

Query: 521 DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580
            +QF I  ++G IT  + LDRE ++ Y L + A D G   L  T  V I V D+ND  P 
Sbjct: 620 -RQFAIGDKSGVITVIRKLDREDLTRYQLLIKAEDSG--GLFSTATVNIKVTDINDKNPE 676

Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640
           F    Y  ++ E       + +V A DAD G+N  I Y   P D     F +DP +G + 
Sbjct: 677 FVGLPYEFSVKEGE-ARKLIGRVHAEDADEGINAEITY-FAPDDI---PFTVDPETGDVL 731

Query: 641 TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700
           T   LD E    +     A DG    + +T  V +K+ D+ D  PVF        + EN 
Sbjct: 732 TKIVLDYEQNDEYKFVVTARDGAPDYRLATATVTVKVIDVEDEVPVFHQSSYEARVKENI 791

Query: 701 PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760
           P   T+ ++ A DPD      + Y IK G D+  F+++ R G  K    T   LDYE   
Sbjct: 792 P-DYTVLQVTADDPD--TKKQITYMIKQG-DTELFAIDQRTGVIK----TTRGLDYERES 843

Query: 761 KKYELV--IRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVP 817
           +   ++  +   S    +  RV + V DVND  PV            D  P+G     + 
Sbjct: 844 QHILIIGTVENTSDLPGSTTRVVVNVQDVNDIPPVFTSVPRPI-TLDDDIPIGTTVINLI 902

Query: 818 AYDADVT---DKLQYRILSGNNAN-LILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
           A D+D T   ++++Y I+    AN   +++  TG + +   L         ++V   D
Sbjct: 903 ATDSDGTAPGNQVRYEIVGRGIANKYFMIDPDTGVLRVRDDLRKETDTEYQVDVRAYD 960



 Score =  235 bits (576), Expect = 1e-59
 Identities = 205/716 (28%), Positives = 325/716 (45%), Gaps = 43/716 (6%)

Query: 62  IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121
           I+ V  D++N               ++ F I+  +GA+    ++D     R+ +++KA +
Sbjct: 277 IQAVDMDSINAPIHYSFLSGNPPNYREFFEINPNTGAVKQIKAVDTTVTKRFDIIIKAVE 336

Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK------IK 175
            +     + S+TA + + +   + N P  +  +    VDE+  +    VI K      + 
Sbjct: 337 VSEA---KRSATAKLTITVKPVDSNPPIITASSIEGFVDENAPI-GTKVIDKDGDPIVLT 392

Query: 176 ATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS--YRLVIRAQDGG 233
            +DAD+G +   + A     T   F+ID     V   + LD +      +R  + A++  
Sbjct: 393 VSDADLGPDDP-KPAYSFELTTNFFAIDPSGMLVVNEENLDRDPPSPGRFRFQVVAREKT 451

Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293
             + S     ++ + DVNDNAP     +      +       + +V+A D DEG NAE+T
Sbjct: 452 GVAASAPLSFVVILNDVNDNAPML--PMIPPITVQAGETKKVVTKVEATDNDEGENAEIT 509

Query: 294 YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353
           Y++      G     I  DPR+G + +  +L+   Q  + + V ATD G    S T    
Sbjct: 510 YSIYHVSNNGLHKFKI--DPRTGVIESVRKLNAGEQ--FSITVQATDKGGK-YSQTIVEV 564

Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS 413
                       F    YEV+++E     + +  + A D + D  + Y I  GN   +F+
Sbjct: 565 NVIPGPNTRSPVFQQPVYEVQVSEGASINSTMTIVHAVDPENDP-VSYSIVSGNDLRQFA 623

Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAP 473
           I  ++G  +ITV + LD +   RY L + A DSGG   TA V I +TD N+  P F   P
Sbjct: 624 IGDKSG--VITVIRKLDREDLTRYQLLIKAEDSGGLFSTATVNIKVTDINDKNPEFVGLP 681

Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
           Y  SV ++      +  V A D+D GINA+ITY           A  D  F ++P+TG +
Sbjct: 682 YEFSV-KEGEARKLIGRVHAEDADEGINAEITY----------FAPDDIPFTVDPETGDV 730

Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593
            T  +LD E    Y   VTARDG       T  V + V+DV D  PVF Q  Y A + E+
Sbjct: 731 LTKIVLDYEQNDEYKFVVTARDGAPDYRLATATVTVKVIDVEDEVPVFHQSSYEARVKEN 790

Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653
            +   +V QV A D D     +I Y +   D E   F ID  +GVI+T + LD E  + H
Sbjct: 791 -IPDYTVLQVTADDPDT--KKQITYMIKQGDTE--LFAIDQRTGVIKTTRGLDYERESQH 845

Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713
            L    ++  +    ST  V + ++D+ND PPVF S      + ++ PIGTT+  + A D
Sbjct: 846 ILIIGTVENTSDLPGSTTRVVVNVQDVNDIPPVFTSVPRPITLDDDIPIGTTVINLIATD 905

Query: 714 PD-EGPNAVVHYSIKGGDDSNSFSL---ETRQGSDKAELVTMVDLDYESPRKKYEL 765
            D   P   V Y I G   +N + +   +T     + +L    D +Y+   + Y++
Sbjct: 906 SDGTAPGNQVRYEIVGRGIANKYFMIDPDTGVLRVRDDLRKETDTEYQVDVRAYDM 961



 Score =  203 bits (495), Expect = 6e-50
 Identities = 246/918 (26%), Positives = 392/918 (42%), Gaps = 85/918 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V   + + P+      E  V E A  GT V+     D+D      +  T+    AD L
Sbjct: 350  ITVKPVDSNPPIITASSIEGFVDENAPIGTKVI-----DKD---GDPIVLTVS--DAD-L 398

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA--RYTVLVKATDQASPVSD 128
             P+D             + F ID     ++   +LDR+  +  R+   V A ++    + 
Sbjct: 399  GPDDPKPAYSFELTT--NFFAIDPSGMLVVNEENLDRDPPSPGRFRFQVVAREKTGVAA- 455

Query: 129  RLSSTATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
              S+  +  V + D NDN P        TV   E        V+ K++ATD D G N+ I
Sbjct: 456  --SAPLSFVVILNDVNDNAPMLPMIPPITVQAGET-----KKVVTKVEATDNDEGENAEI 508

Query: 188  RYAI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
             Y+I  +  N   +F ID  +G +  V+ L+  +   + + ++A D G        ++ +
Sbjct: 509  TYSIYHVSNNGLHKFKIDPRTGVIESVRKLNAGE--QFSITVQATDKGGKYSQTIVEVNV 566

Query: 246  NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
             I   N  +P F   +++  VSE   I  ++  V A D +   N  ++Y++     +GN 
Sbjct: 567  -IPGPNTRSPVFQQPVYEVQVSEGASINSTMTIVHAVDPE---NDPVSYSIV----SGND 618

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
                 I  +SG +    +LDRE   +YQLL+ A D G     +TAT              
Sbjct: 619  LRQFAIGDKSGVITVIRKLDREDLTRYQLLIKAEDSGG--LFSTATVNIKVTDINDKNPE 676

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG-RFSITSQNGRGLIT 424
            F+   YE  + E E     +  + A DADE   ++ EIT        F++  + G  L  
Sbjct: 677  FVGLPYEFSVKEGEARKL-IGRVHAEDADEG--INAEITYFAPDDIPFTVDPETGDVLTK 733

Query: 425  VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
            +   LD++Q   Y   V+A D     R  TA V + + D  +  PVF  + Y A V E+ 
Sbjct: 734  IV--LDYEQNDEYKFVVTARDGAPDYRLATATVTVKVIDVEDEVPVFHQSSYEARVKENI 791

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
            P   TVL V+A D D     QITY +    +        + F I+ +TG I T + LD E
Sbjct: 792  P-DYTVLQVTADDPDT--KKQITYMIKQGDT--------ELFAIDQRTGVIKTTRGLDYE 840

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
              S ++L +   +        TT V ++V DVND  PVF        + +D  +GT+V  
Sbjct: 841  RESQHILIIGTVENTSDLPGSTTRVVVNVQDVNDIPPVFTSVPRPITLDDDIPIGTTVIN 900

Query: 603  VGATDADVGLNG-RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
            + ATD+D    G ++ YE+  +      F+IDP +GV+R    L +E+   + +   A D
Sbjct: 901  LIATDSDGTAPGNQVRYEIVGRGIANKYFMIDPDTGVLRVRDDLRKETDTEYQVDVRAYD 960

Query: 662  GGTPPQSSTVIVHIKIEDINDSPPV----FESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
             G P  SS   V + +  +   PP     F  +     + E++   T I  I   +    
Sbjct: 961  MGEPQLSSVTTVPVYVRHVATVPPEIGLGFAENSYNVEVPEDAGDNTLIKIITIINSHAH 1020

Query: 718  PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS-PPLWN 776
                +   I  G++ + F     +  + A  +    LDYE+  + Y++ I+  S   L N
Sbjct: 1021 DTTPLKCEIYSGNEDDLFEAGVTEERNCALKLKKGALDYET-TESYQVKIKLESLSGLLN 1079

Query: 777  DVR----VEILVTDVNDNAPVM----KDFQIIFNNYKDCFP-VGPFG----RVPAYDAD- 822
              R    V+I V DVNDN P       D ++    Y    P    FG    +V A+D D 
Sbjct: 1080 SGRNTTMVKIQVVDVNDNKPEFIFPENDLKLSRGRYFAAIPRSAQFGSTVIQVKAHDKDN 1139

Query: 823  -VTDKLQYRILSGNNANLILLNETTGSM-TLSPQLNTNVPKLA-TMEVSVTDGVNEI--- 876
                KL+YRIL G  ++   ++ ++G + T +   N +  +L    +V V D  N     
Sbjct: 1140 GKYGKLEYRILGGRGSDYFAMDTSSGIIRTTATFDNVDPAELPFKFDVRVRDNPNSTDNF 1199

Query: 877  -KAMMQLSVRLITEEMLL 893
               +  + V LI EE L+
Sbjct: 1200 NSIVAPVIVNLIGEENLM 1217



 Score =  184 bits (449), Expect = 2e-44
 Identities = 222/818 (27%), Positives = 349/818 (42%), Gaps = 97/818 (11%)

Query: 87  QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146
           Q  F+++G+   LL     D E ++     +  T + +        T  + V + D NDN
Sbjct: 52  QPRFKLNGKRLQLLEPLDRDDENLSHVVFQLSCTVKQT----NKKRTIPVIVRVSDINDN 107

Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI-------IGGNTQM- 198
            P+F    Y  +V E ++   + +   + A DAD G N  + Y+I       IG N  + 
Sbjct: 108 APKFINTPYETTVPE-LTPVGSTIFKNVVAVDADAGVNGIVEYSIAPGDGTGIGNNDGVG 166

Query: 199 -----------QFSID-SLSGDVSLVKTLDYEQVRSYRLVIRAQDGG---SPSRSNTTQL 243
                       FSI+    G V++ +TLD+E+ + Y + I A D     S   ++TT L
Sbjct: 167 RNRITTADGYGYFSINLPHQGQVTVNRTLDFERTQRYLVTILASDRARNVSERFTSTTTL 226

Query: 244 LINIRDVNDNAPRF-YTSL-----------FQESVSENVPIG---YSIVRVQAYDADEGV 288
            +NIRD +D  P F Y              +  SVS  V  G    S  ++QA D D  +
Sbjct: 227 TVNIRDDDDQDPSFIYQGCMLLDGACINPEYSASVSSGVLSGILNISPEKIQAVDMD-SI 285

Query: 289 NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348
           NA + Y+    +   N      I+P +G V     +D     ++ +++ A +  +  RSA
Sbjct: 286 NAPIHYSFLSGN-PPNYREFFEINPNTGAVKQIKAVDTTVTKRFDIIIKAVEVSEAKRSA 344

Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV-------VTLTATDAD---EDNR 398
           TA                     E  + E+ P GT V       + LT +DAD   +D +
Sbjct: 345 TAKLTITVKPVDSNPPIITASSIEGFVDENAPIGTKVIDKDGDPIVLTVSDADLGPDDPK 404

Query: 399 LHYEITGGNTRGRFSITSQNGRGLITVAQ---PLDFKQERRYVLTVSATDSGGRSDTAMV 455
             Y      T   F+I   +  G++ V +     D     R+   V A +  G + +A +
Sbjct: 405 PAYSFE--LTTNFFAI---DPSGMLVVNEENLDRDPPSPGRFRFQVVAREKTGVAASAPL 459

Query: 456 Q--INITDANNYAPVFEN-APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512
              + + D N+ AP+     P T    E   +   V  V ATD+D G NA+ITYS+   +
Sbjct: 460 SFVVILNDVNDNAPMLPMIPPITVQAGETKKV---VTKVEATDNDEGENAEITYSI-YHV 515

Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572
           SN  +     +F I+P+TG I + + L+      + +TV A D G       T VE++V+
Sbjct: 516 SNNGL----HKFKIDPRTGVIESVRKLNAGEQ--FSITVQATDKG--GKYSQTIVEVNVI 567

Query: 573 -DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631
              N   PVF+Q +Y   + E A + ++++ V A D +   N  + Y +     +   F 
Sbjct: 568 PGPNTRSPVFQQPVYEVQVSEGASINSTMTIVHAVDPE---NDPVSYSI-VSGNDLRQFA 623

Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691
           I   SGVI   + LDRE +  + L   A D G     ST  V+IK+ DIND  P F    
Sbjct: 624 IGDKSGVITVIRKLDREDLTRYQLLIKAEDSG--GLFSTATVNIKVTDINDKNPEFVGLP 681

Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751
             F + E       IG + A D DEG NA + Y      D   F+++   G    +++T 
Sbjct: 682 YEFSVKEGE-ARKLIGRVHAEDADEGINAEITYF---APDDIPFTVDPETG----DVLTK 733

Query: 752 VDLDYE-SPRKKYELVIRAASPPL-WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809
           + LDYE +   K+ +  R  +P        V + V DV D  PV           K+  P
Sbjct: 734 IVLDYEQNDEYKFVVTARDGAPDYRLATATVTVKVIDVEDEVPVFHQ-SSYEARVKENIP 792

Query: 810 VGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTG 847
                +V A D D   ++ Y I  G +  L  +++ TG
Sbjct: 793 DYTVLQVTADDPDTKKQITYMIKQG-DTELFAIDQRTG 829



 Score =  119 bits (286), Expect = 1e-24
 Identities = 128/454 (28%), Positives = 209/454 (46%), Gaps = 68/454 (14%)

Query: 394 DEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER--RYVLTVSAT-DSGGRS 450
           D  N    E+     + RF +   NG+ L  + +PLD   E     V  +S T     + 
Sbjct: 37  DPYNETTLELIFPGRQPRFKL---NGKRL-QLLEPLDRDDENLSHVVFQLSCTVKQTNKK 92

Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV-VSATDSDVGINAQITYSLS 509
            T  V + ++D N+ AP F N PY  +V E  P+G+T+   V A D+D G+N  + YS++
Sbjct: 93  RTIPVIVRVSDINDNAPKFINTPYETTVPELTPVGSTIFKNVVAVDADAGVNGIVEYSIA 152

Query: 510 ----SEISNE--------AVAHHDQQFVIN-PQTGAITTNKLLDRETMSGYLLTVTARDG 556
               + I N           A     F IN P  G +T N+ LD E    YL+T+ A D 
Sbjct: 153 PGDGTGIGNNDGVGRNRITTADGYGYFSINLPHQGQVTVNRTLDFERTQRYLVTILASDR 212

Query: 557 G---VPSLSDTTDVEISVVDVNDNEPVFKQQ------------LYTANIMEDALVG---T 598
                   + TT + +++ D +D +P F  Q             Y+A++    L G    
Sbjct: 213 ARNVSERFTSTTTLTVNIRDDDDQDPSFIYQGCMLLDGACINPEYSASVSSGVLSGILNI 272

Query: 599 SVSQVGATDADVGLNGRIHYEL---DPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655
           S  ++ A D D  +N  IHY     +P +  E  F I+P +G ++  KA+D       D+
Sbjct: 273 SPEKIQAVDMD-SINAPIHYSFLSGNPPNYRE-FFEINPNTGAVKQIKAVDTTVTKRFDI 330

Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
              A++     +S+T  + I ++ ++ +PP+  +  +  ++ EN+PIGT     +  D D
Sbjct: 331 IIKAVEVSEAKRSATAKLTITVKPVDSNPPIITASSIEGFVDENAPIGT-----KVIDKD 385

Query: 716 EGPNAV-VHYSIKGGDD---SNSFSLETR-QGSDKAELVTM----VDLDYESP-RKKYEL 765
             P  + V  +  G DD   + SF L T     D + ++ +    +D D  SP R ++++
Sbjct: 386 GDPIVLTVSDADLGPDDPKPAYSFELTTNFFAIDPSGMLVVNEENLDRDPPSPGRFRFQV 445

Query: 766 VIR-----AASPPLWNDVRVEILVTDVNDNAPVM 794
           V R     AAS PL       +++ DVNDNAP++
Sbjct: 446 VAREKTGVAASAPL----SFVVILNDVNDNAPML 475



 Score = 37.5 bits (83), Expect = 5.3
 Identities = 22/62 (35%), Positives = 34/62 (54%), Gaps = 9/62 (14%)

Query: 10   QINVLDCNDHSPVF---------EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEY 60
            +I V+D ND+ P F            +Y A++   A  G+TV+ +KA D+D GK  ++EY
Sbjct: 1088 KIQVVDVNDNKPEFIFPENDLKLSRGRYFAAIPRSAQFGSTVIQVKAHDKDNGKYGKLEY 1147

Query: 61   TI 62
             I
Sbjct: 1148 RI 1149


>UniRef50_Q60I71 Cluster: Cadherin-related neuronal receptor
           variable 6; n=16; Clupeocephala|Rep: Cadherin-related
           neuronal receptor variable 6 - Danio rerio (Zebrafish)
           (Brachydanio rerio)
          Length = 939

 Score =  255 bits (625), Expect = 1e-65
 Identities = 182/601 (30%), Positives = 280/601 (46%), Gaps = 31/601 (5%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F ++ ++G L  +  LDRE++   ++  K   +   + +   +     VN++D NDN P 
Sbjct: 72  FDVNMKTGILQVKDKLDREEICGQSL--KCALELEAIVNSPLNMYRFEVNVLDVNDNSPT 129

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG-- 207
           F      ++V E   + +   +    A DADVG NS   Y +   +    FS+D+ SG  
Sbjct: 130 FPSSRLQLNVSEAAFIGERYALPN--AFDADVGINSVKSYKL---SANEHFSLDAQSGGE 184

Query: 208 -----DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLF 262
                ++ L K LD E+    RL + A DGG P RS T  +++N+ DVNDN P F  SL+
Sbjct: 185 QSVSAELVLQKALDREKQPVIRLTLTAVDGGKPPRSGTVHIIVNVIDVNDNIPVFTKSLY 244

Query: 263 QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322
           +  + EN P+ +S++ V A DAD G+N E+ Y+        N++    I+  +G +   G
Sbjct: 245 KARILENAPVEFSVITVNARDADAGLNGEIEYSFIKHGIDKNIE-SFAINKETGEITVMG 303

Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382
           +LD E+    ++ V A D G  PR A                          + E  P G
Sbjct: 304 KLDHESNNAIEIRVQARDKGSTPRVAHCKVLVEIMDVNDNIPEISVTSLINVVKEGSPKG 363

Query: 383 TPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440
           T V  +T  D D  E+  +  +I   +       T +N   L+ V  PLD +    Y +T
Sbjct: 364 TMVGLITVKDDDSGENGSVKLKIL-DSLPFALQNTYKNKYSLV-VDGPLDRESASEYNVT 421

Query: 441 VSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498
           +SA D G    S T+++ ++++D N+ AP F        V E++ IG  +  VSA D DV
Sbjct: 422 ISAADEGSPPLSSTSVIAVHVSDVNDNAPRFPEPVINVYVKENSQIGAVLHTVSAVDPDV 481

Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558
           G NA+ITYSL     +  V        IN  TG + + +  + E +  +   V A D GV
Sbjct: 482 GDNARITYSLLESSKSGPVT---SMININSDTGDLHSLQSFNYEEIKTFEFKVQATDSGV 538

Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQ------QLYTANIMEDALVGTSVSQVGATDADVGL 612
           P LS    V + V+D NDN P           + T NI   A  G  V+++ A DAD G 
Sbjct: 539 PPLSSNVTVNVFVLDENDNSPAILAPYSELGSVNTENIPYSAEAGYFVAKIRAVDADSGY 598

Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672
           N  + Y +  + +    F I  +SG IRT + +    + TH L  +  D G P  S+TV 
Sbjct: 599 NALLSYHIS-EPKGNNLFRIGTSSGEIRTKRRMSDNDLKTHPLVILVCDNGEPSLSATVS 657

Query: 673 V 673
           +
Sbjct: 658 I 658



 Score =  194 bits (472), Expect = 4e-47
 Identities = 140/479 (29%), Positives = 230/479 (48%), Gaps = 26/479 (5%)

Query: 412 FSITSQNG-----RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANN 464
           FS+ +Q+G        + + + LD +++    LT++A D G   RS T  + +N+ D N+
Sbjct: 175 FSLDAQSGGEQSVSAELVLQKALDREKQPVIRLTLTAVDGGKPPRSGTVHIIVNVIDVND 234

Query: 465 YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524
             PVF  + Y A + E+AP+  +V+ V+A D+D G+N +I YS         +  + + F
Sbjct: 235 NIPVFTKSLYKARILENAPVEFSVITVNARDADAGLNGEIEYSFIKH----GIDKNIESF 290

Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584
            IN +TG IT    LD E+ +   + V ARD G         V + ++DVNDN P     
Sbjct: 291 AINKETGEITVMGKLDHESNNAIEIRVQARDKGSTPRVAHCKVLVEIMDVNDNIPEISVT 350

Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGVIRTNK 643
                + E +  GT V  +   D D G NG +  + LD       +   +  S V+  + 
Sbjct: 351 SLINVVKEGSPKGTMVGLITVKDDDSGENGSVKLKILDSLPFALQNTYKNKYSLVV--DG 408

Query: 644 ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703
            LDRES + +++   A D G+PP SST ++ + + D+ND+ P F    +  Y+ ENS IG
Sbjct: 409 PLDRESASEYNVTISAADEGSPPLSSTSVIAVHVSDVNDNAPRFPEPVINVYVKENSQIG 468

Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY 763
             +  + A DPD G NA + YS+     S   +      SD  +L ++   +YE   K +
Sbjct: 469 AVLHTVSAVDPDVGDNARITYSLLESSKSGPVTSMININSDTGDLHSLQSFNYEE-IKTF 527

Query: 764 ELVIRAAS---PPLWNDVRVEILVTDVNDNAP-VMKDFQIIFNNYKDCFP----VGPF-G 814
           E  ++A     PPL ++V V + V D NDN+P ++  +  + +   +  P     G F  
Sbjct: 528 EFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAILAPYSELGSVNTENIPYSAEAGYFVA 587

Query: 815 RVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
           ++ A DAD      L Y I      NL  +  ++G +    +++ N  K   + + V D
Sbjct: 588 KIRAVDADSGYNALLSYHISEPKGNNLFRIGTSSGEIRTKRRMSDNDLKTHPLVILVCD 646



 Score =  185 bits (450), Expect = 2e-44
 Identities = 159/583 (27%), Positives = 257/583 (44%), Gaps = 54/583 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++NVLD ND+SP F   + + +V E A  G       A D D+G N+   Y +      +
Sbjct: 117 EVNVLDVNDNSPTFPSSRLQLNVSEAAFIGERYALPNAFDADVGINSVKSYKLSANEHFS 176

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
           L+ +             Q V      S  L+ + +LDREK     + + A D   P    
Sbjct: 177 LDAQSGGE---------QSV------SAELVLQKALDREKQPVIRLTLTAVDGGKPPR-- 219

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            S T  I VN+ID NDN P F++  Y   + E+  V  +  +  + A DAD G N  I Y
Sbjct: 220 -SGTVHIIVNVIDVNDNIPVFTKSLYKARILENAPVEFS--VITVNARDADAGLNGEIEY 276

Query: 190 AII--GGNTQMQ-FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           + I  G +  ++ F+I+  +G+++++  LD+E   +  + ++A+D GS  R    ++L+ 
Sbjct: 277 SFIKHGIDKNIESFAINKETGEITVMGKLDHESNNAIEIRVQARDKGSTPRVAHCKVLVE 336

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
           I DVNDN P    +     V E  P G  +  +   D D G N  +   + D        
Sbjct: 337 IMDVNDNIPEISVTSLINVVKEGSPKGTMVGLITVKDDDSGENGSVKLKILDS------- 389

Query: 307 LPITIDPRSGWVYT---SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
           LP  +       Y+    G LDRE+ ++Y + ++A D G PP S+T+             
Sbjct: 390 LPFALQNTYKNKYSLVVDGPLDRESASEYNVTISAADEGSPPLSSTSVIAVHVSDVNDNA 449

Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRGRFS--ITSQNG 419
             F      V + E+   G  + T++A D D  DN R+ Y +   +  G  +  I   + 
Sbjct: 450 PRFPEPVINVYVKENSQIGAVLHTVSAVDPDVGDNARITYSLLESSKSGPVTSMININSD 509

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPY--- 474
            G +   Q  ++++ + +   V ATDSG    S    V + + D N+ +P    APY   
Sbjct: 510 TGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAIL-APYSEL 568

Query: 475 ----TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
               T ++   A  G  V  + A D+D G NA ++Y +S    N         F I   +
Sbjct: 569 GSVNTENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKGNNL-------FRIGTSS 621

Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
           G I T + +    +  + L +   D G PSLS T  ++  VV+
Sbjct: 622 GEIRTKRRMSDNDLKTHPLVILVCDNGEPSLSATVSIDAVVVE 664



 Score =  154 bits (374), Expect = 3e-35
 Identities = 137/502 (27%), Positives = 220/502 (43%), Gaps = 40/502 (7%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           +H  +NV+D ND+ PVF    Y+A + E A    +V+T+ A D D G N E+EY+     
Sbjct: 223 VHIIVNVIDVNDNIPVFTKSLYKARILENAPVEFSVITVNARDADAGLNGEIEYSFIKHG 282

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
            D  N E                F I+  +G +     LD E      + V+A D+ S  
Sbjct: 283 IDK-NIES---------------FAINKETGEITVMGKLDHESNNAIEIRVQARDKGS-- 324

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
           + R++    + V I+D NDN P+ S  T  ++V ++ S     ++  I   D D G N +
Sbjct: 325 TPRVAHCKVL-VEIMDVNDNIPEISV-TSLINVVKEGS-PKGTMVGLITVKDDDSGENGS 381

Query: 187 IRYAIIGGNTQMQFSI-DSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
           ++  I+     + F++ ++     SLV    LD E    Y + I A D GSP  S+T+ +
Sbjct: 382 VKLKILDS---LPFALQNTYKNKYSLVVDGPLDRESASEYNVTISAADEGSPPLSSTSVI 438

Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
            +++ DVNDNAPRF   +    V EN  IG  +  V A D D G NA +TY++ +   +G
Sbjct: 439 AVHVSDVNDNAPRFPEPVINVYVKENSQIGAVLHTVSAVDPDVGDNARITYSLLESSKSG 498

Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
            V   I I+  +G +++    + E    ++  V ATD G PP S+  T            
Sbjct: 499 PVTSMININSDTGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNS 558

Query: 364 XXFMPGQYEVELAEDE------PPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSIT 415
              +    E+     E        G  V  + A DAD   +  L Y I+       F I 
Sbjct: 559 PAILAPYSELGSVNTENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKGNNLFRIG 618

Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN---ITDANNYAPVFENA 472
           + +G   I   + +     + + L +   D+G  S +A V I+   +    +    F +A
Sbjct: 619 TSSGE--IRTKRRMSDNDLKTHPLVILVCDNGEPSLSATVSIDAVVVESGGDVKTPFRHA 676

Query: 473 PYTASVFEDAPIGTTVLVVSAT 494
           P     F D  +   + +VS +
Sbjct: 677 PVKEESFSDLNLYLLIAIVSVS 698



 Score =  141 bits (341), Expect = 3e-31
 Identities = 116/370 (31%), Positives = 169/370 (45%), Gaps = 24/370 (6%)

Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523
           N  P   +     SV E+A  GTTV  +     ++ +N Q       +I    V  + + 
Sbjct: 19  NILPRISSGQIAFSVSEEASPGTTVGNIV---KELNLNLQELEHRGFQI----VGPNKRY 71

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVNDNEPVFK 582
           F +N +TG +     LDRE + G  L      +  V S  +    E++V+DVNDN P F 
Sbjct: 72  FDVNMKTGILQVKDKLDREEICGQSLKCALELEAIVNSPLNMYRFEVNVLDVNDNSPTFP 131

Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR---EEGSFVIDPASGVI 639
                 N+ E A +G   +   A DADVG+N    Y+L   +    +  S      S  +
Sbjct: 132 SSRLQLNVSEAAFIGERYALPNAFDADVGINSVKSYKLSANEHFSLDAQSGGEQSVSAEL 191

Query: 640 RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699
              KALDRE      L   A+DGG PP+S TV + + + D+ND+ PVF        I EN
Sbjct: 192 VLQKALDREKQPVIRLTLTAVDGGKPPRSGTVHIIVNVIDVNDNIPVFTKSLYKARILEN 251

Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYS-IKGGDDSN--SFSLETRQGSDKAELVTMVDLDY 756
           +P+  ++  + A D D G N  + YS IK G D N  SF++    G    E+  M  LD+
Sbjct: 252 APVEFSVITVNARDADAGLNGEIEYSFIKHGIDKNIESFAINKETG----EITVMGKLDH 307

Query: 757 ESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF 813
           ES     E+ ++A    S P     +V + + DVNDN P +    +I N  K+  P G  
Sbjct: 308 ES-NNAIEIRVQARDKGSTPRVAHCKVLVEIMDVNDNIPEISVTSLI-NVVKEGSPKGTM 365

Query: 814 -GRVPAYDAD 822
            G +   D D
Sbjct: 366 VGLITVKDDD 375



 Score = 77.0 bits (181), Expect = 7e-12
 Identities = 74/295 (25%), Positives = 123/295 (41%), Gaps = 17/295 (5%)

Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648
           ++ E+A  GT+V  +   + ++ L    H         +  F ++  +G+++    LDRE
Sbjct: 32  SVSEEASPGTTVGNI-VKELNLNLQELEHRGFQIVGPNKRYFDVNMKTGILQVKDKLDRE 90

Query: 649 SVATHDLK-AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
            +    LK A+ ++       +     + + D+ND+ P F S  L   +SE + IG    
Sbjct: 91  EICGQSLKCALELEAIVNSPLNMYRFEVNVLDVNDNSPTFPSSRLQLNVSEAAFIGERYA 150

Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK---AELVTMVDLDYE-SPRKKY 763
              A D D G N+V  Y +   +    FSL+ + G ++   AELV    LD E  P  + 
Sbjct: 151 LPNAFDADVGINSVKSYKLSANE---HFSLDAQSGGEQSVSAELVLQKALDREKQPVIRL 207

Query: 764 EL-VIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQI---IFNNYKDCFPVGPFGRVPAY 819
            L  +    PP    V + + V DVNDN PV         I  N    F V       A 
Sbjct: 208 TLTAVDGGKPPRSGTVHIIVNVIDVNDNIPVFTKSLYKARILENAPVEFSVITVNARDA- 266

Query: 820 DADVTDKLQYRILS---GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
           DA +  +++Y  +      N     +N+ TG +T+  +L+        + V   D
Sbjct: 267 DAGLNGEIEYSFIKHGIDKNIESFAINKETGEITVMGKLDHESNNAIEIRVQARD 321



 Score = 37.5 bits (83), Expect = 5.3
 Identities = 43/174 (24%), Positives = 76/174 (43%), Gaps = 7/174 (4%)

Query: 685 PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK-GGDDSNSFSLETRQG- 742
           P   S  + F +SE +  GTT+G I   + +     + H   +  G +   F +  + G 
Sbjct: 22  PRISSGQIAFSVSEEASPGTTVGNI-VKELNLNLQELEHRGFQIVGPNKRYFDVNMKTGI 80

Query: 743 SDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN 802
               + +   ++  +S +   EL     SP   N  R E+ V DVNDN+P     ++  N
Sbjct: 81  LQVKDKLDREEICGQSLKCALELEAIVNSP--LNMYRFEVNVLDVNDNSPTFPSSRLQLN 138

Query: 803 NYKDCFPVGPFGRVPAYDADV-TDKLQYRILSGNNANLILLNETTGSMTLSPQL 855
             +  F    +    A+DADV  + ++   LS N  +  L  ++ G  ++S +L
Sbjct: 139 VSEAAFIGERYALPNAFDADVGINSVKSYKLSANE-HFSLDAQSGGEQSVSAEL 191


>UniRef50_Q7PUW9 Cluster: ENSANGP00000018135; n=2; Anopheles
            gambiae|Rep: ENSANGP00000018135 - Anopheles gambiae str.
            PEST
          Length = 1880

 Score =  254 bits (621), Expect = 3e-65
 Identities = 222/765 (29%), Positives = 344/765 (44%), Gaps = 72/765 (9%)

Query: 13   VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKAT-----DQDIGKNAEVEYTIELVTA 67
            V D ND  P F    YE  + E A   T    +  +     D D GKN     T  L   
Sbjct: 387  VTDVNDEIPRFRSDGYECEIGENAQENTLARFIDGSINEVFDYDQGKNG----TFRL--- 439

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
             +L+P              +  F +  +  ++     LD E+V   ++ V A++  S  +
Sbjct: 440  -SLHPPSDIFEVIPKRAINEATFGLRVKDPSM-----LDYERVRELSLTVVASEVES--A 491

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG--ANS 185
             R +STA I V ++D NDN+P+FS+  Y + V E  +VT   V+ +++ATD+D G     
Sbjct: 492  GR-TSTAQIRVVVLDQNDNFPEFSQPVYEIDVPE--NVTAGTVLLQLQATDSDSGLFGTE 548

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKT----LDYEQVRSYRLVIRAQDGGSPSRSNTT 241
             +RYA + G+      +D  +G V+L+ +     D E ++ + L + A+D G     NT 
Sbjct: 549  GVRYANLTGSISSFLHLDPHAGTVTLMASESPVFDREIIQKHYLSVEARDNGGRGNRNTV 608

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EG-VNAELTYTMT-- 297
             L++N+ DVNDNAP F    ++  + EN     S + V+A D+D EG  N+ + Y +   
Sbjct: 609  PLILNVLDVNDNAPVFVQKRYEVRLKENAFEFESPIVVEARDSDLEGSPNSAVEYRLIGA 668

Query: 298  -DKDY------TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350
               DY      TG + +   +D       + G  D  T A   L + A DGG+PP +A  
Sbjct: 669  HHSDYFHVDRRTGRLSVREAVD-FERLESSGGSGDTRTIA---LTIEAADGGEPPLTAQV 724

Query: 351  TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGN 407
                           F+  QY + + ED P G PV+ +TA D D    +N + Y I  G 
Sbjct: 725  EVTVYVQDVNDYAPVFLESQYAIVIPEDTPSGLPVLRVTAMDGDGSFPNNHVTYRIQQGG 784

Query: 408  TRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAP 467
              GRF I +  G   IT    LD          + A D+ G   T ++++  TD  N   
Sbjct: 785  D-GRFVIGASTGEISITHGASLD--------PNLLAPDALGSGSTYVLEVFATDGGNGDQ 835

Query: 468  VFENAPYTASVFEDAPIGTTVLVVSATDSDVG--INAQITYSLSSEISNE-AVAHHDQ-- 522
              +     + +  + P+GT V  + ATD D G  +   I  SLS   + E A+   D   
Sbjct: 836  QLQG----SCLVNNTPVGTEVYRLMATDPDEGAMLRYYIDRSLSEGKTEEGALVKLDDYD 891

Query: 523  ---QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP--SLSDTTDVEISVVDVNDN 577
                F++N   G +   KLLDRE ++   L     D           T ++I+V+D NDN
Sbjct: 892  FAAAFILNETNGLLKIAKLLDREKIAEIKLACVVEDVAAERGDQMANTFLKITVLDENDN 951

Query: 578  EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637
             P F++  Y  +I E++  G +V  V A DAD   N  + Y L+ +        +D  +G
Sbjct: 952  NPKFRKPFYKHSIAENSQYGVAVCTVVAEDAD--QNKTVKYSLEGEKGVLELLHVDDETG 1009

Query: 638  VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697
             I     +D E  +  +    A D GTPP++S V V +++ D ND+ P F      +Y+S
Sbjct: 1010 EIVVRNRIDHEEYSWLNFSVRAADTGTPPRASFVEVFVQVLDENDNNPYFVDSVNDYYVS 1069

Query: 698  ENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
            EN+ +G  I  I A D D G    + Y +        FS++  +G
Sbjct: 1070 ENASVGAEIAIILAKDLDSGDFGRITYILDRVSSKEKFSIDPEKG 1114



 Score =  245 bits (600), Expect = 1e-62
 Identities = 240/906 (26%), Positives = 393/906 (43%), Gaps = 89/906 (9%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ VLD ND+ P F    YE  V E  ++GT +L L+ATD D G      +  E V    
Sbjct: 500  RVVVLDQNDNFPEFSQPVYEIDVPENVTAGTVLLQLQATDSDSGL-----FGTEGVRYAN 554

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS----LDREKVARYTVLVKATDQASP 125
            L               +     +D  +G +   AS     DRE + ++ + V+A D    
Sbjct: 555  L------------TGSISSFLHLDPHAGTVTLMASESPVFDREIIQKHYLSVEARDNGGR 602

Query: 126  VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
             +    +T  + +N++D NDN P F +K Y V + E+    ++P++ + + +D +   NS
Sbjct: 603  GN---RNTVPLILNVLDVNDNAPVFVQKRYEVRLKENAFEFESPIVVEARDSDLEGSPNS 659

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV---------RSYRLVIRAQDGGSPS 236
            A+ Y +IG +    F +D  +G +S+ + +D+E++         R+  L I A DGG P 
Sbjct: 660  AVEYRLIGAHHSDYFHVDRRTGRLSVREAVDFERLESSGGSGDTRTIALTIEAADGGEPP 719

Query: 237  RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV-NAELTYT 295
             +   ++ + ++DVND AP F  S +   + E+ P G  ++RV A D D    N  +TY 
Sbjct: 720  LTAQVEVTVYVQDVNDYAPVFLESQYAIVIPEDTPSGLPVLRVTAMDGDGSFPNNHVTYR 779

Query: 296  MT---DKDY-----TGNVDLP--ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP 345
            +    D  +     TG + +    ++DP    +     L   + + Y L V ATDGG+  
Sbjct: 780  IQQGGDGRFVIGASTGEISITHGASLDPN---LLAPDALG--SGSTYVLEVFATDGGNGD 834

Query: 346  RSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV---VTLTATDADEDNRLHYE 402
            +    +               M        A D   G  +   +  + ++   +     +
Sbjct: 835  QQLQGSCLVNNTPVGTEVYRLM--------ATDPDEGAMLRYYIDRSLSEGKTEEGALVK 886

Query: 403  ITGGNTRGRFSITSQNGRGLITVAQPLDFKQ--ERRYVLTVS--ATDSGGRSDTAMVQIN 458
            +   +    F +   N  GL+ +A+ LD ++  E +    V   A + G +     ++I 
Sbjct: 887  LDDYDFAAAFILNETN--GLLKIAKLLDREKIAEIKLACVVEDVAAERGDQMANTFLKIT 944

Query: 459  ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518
            + D N+  P F    Y  S+ E++  G  V  V A D+D   N  + YSL  E     + 
Sbjct: 945  VLDENDNNPKFRKPFYKHSIAENSQYGVAVCTVVAEDADQ--NKTVKYSLEGEKGVLELL 1002

Query: 519  HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578
            H      ++ +TG I     +D E  S    +V A D G P  +   +V + V+D NDN 
Sbjct: 1003 H------VDDETGEIVVRNRIDHEEYSWLNFSVRAADTGTPPRASFVEVFVQVLDENDNN 1056

Query: 579  PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638
            P F   +    + E+A VG  ++ + A D D G  GRI Y LD    +E  F IDP  G+
Sbjct: 1057 PYFVDSVNDYYVSENASVGAEIAIILAKDLDSGDFGRITYILDRVSSKE-KFSIDPEKGI 1115

Query: 639  IRTNKALDRESVATHDLKAVAID----GGTPPQSSTVIVHIKIE--DINDSPPVFESDCL 692
            +R   ALDRE  A + L   A D    G    +S     HI I   D ND+ PV +    
Sbjct: 1116 LRVAGALDREETAEYMLAVEAWDNYPYGYLNGESRNAFKHILIHVLDDNDNVPVIQKPSG 1175

Query: 693  TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752
               I+E   I   I ++RA D D+  N     S    D S  F ++ +  +  AE+ +  
Sbjct: 1176 CSMITEYHNINDPIVKLRATDADDPTNGNGQLSFDIVDPSGIFYIQ-QVSAQYAEIYSRG 1234

Query: 753  DLDYESPRKKYELVIR-AASPPLWNDVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFP 809
             L         EL++      P      V+I VTD ND+AP  V+         +++   
Sbjct: 1235 PLKNLHGNYTLELIVSDLGGVPNTARETVDICVTDFNDHAPVFVVPSGNTTVKVFENTTL 1294

Query: 810  VGPFGRVPAYDADVTDK--LQYRILSGNNANL--ILLNETTGSMTLSPQLNTNVPKLATM 865
              PF +V AYD DV +   ++YR+      N     L++ TG ++L+  L+     +  +
Sbjct: 1295 GKPFFQVHAYDEDVGENAIVRYRLKMDTMGNFRKFSLDKETGELSLAASLDREQQMMYDL 1354

Query: 866  EVSVTD 871
             +   D
Sbjct: 1355 RIEAYD 1360



 Score =  239 bits (584), Expect = 1e-60
 Identities = 210/718 (29%), Positives = 323/718 (44%), Gaps = 53/718 (7%)

Query: 39   GTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGA 98
            GT V  L ATD D G  A + Y I+   ++    E A              F ++  +G 
Sbjct: 849  GTEVYRLMATDPDEG--AMLRYYIDRSLSEGKTEEGALVKLDDYDFAA--AFILNETNGL 904

Query: 99   LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158
            L     LDREK+A   +     D A+   D++++T  + + ++D+NDN P+F +  Y  S
Sbjct: 905  LKIAKLLDREKIAEIKLACVVEDVAAERGDQMANTF-LKITVLDENDNNPKFRKPFYKHS 963

Query: 159  VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQF-SIDSLSGDVSLVKTLDY 217
            + E+        +  + A DAD   N  ++Y++ G    ++   +D  +G++ +   +D+
Sbjct: 964  IAENSQY--GVAVCTVVAEDAD--QNKTVKYSLEGEKGVLELLHVDDETGEIVVRNRIDH 1019

Query: 218  EQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277
            E+       +RA D G+P R++  ++ + + D NDN P F  S+    VSEN  +G  I 
Sbjct: 1020 EEYSWLNFSVRAADTGTPPRASFVEVFVQVLDENDNNPYFVDSVNDYYVSENASVGAEIA 1079

Query: 278  RVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVT 337
             + A D D G    +TY +   D   + +   +IDP  G +  +G LDRE  A+Y L V 
Sbjct: 1080 IILAKDLDSGDFGRITYIL---DRVSSKE-KFSIDPEKGILRVAGALDREETAEYMLAVE 1135

Query: 338  ATDG------GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTAT 391
            A D           R+A                          + E      P+V L AT
Sbjct: 1136 AWDNYPYGYLNGESRNAFKHILIHVLDDNDNVPVIQKPSGCSMITEYHNINDPIVKLRAT 1195

Query: 392  DADE----DNRLHYEITGGNTRGRFSITSQNGR-GLITVAQPLDFKQERRYVLTVSATDS 446
            DAD+    + +L ++I   +  G F I   + +   I    PL       Y L +  +D 
Sbjct: 1196 DADDPTNGNGQLSFDIV--DPSGIFYIQQVSAQYAEIYSRGPLK-NLHGNYTLELIVSDL 1252

Query: 447  GGRSDTAM--VQINITDANNYAPVF--ENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502
            GG  +TA   V I +TD N++APVF   +   T  VFE+  +G     V A D DVG NA
Sbjct: 1253 GGVPNTARETVDICVTDFNDHAPVFVVPSGNTTVKVFENTTLGKPFFQVHAYDEDVGENA 1312

Query: 503  QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS-L 561
             + Y L  +          ++F ++ +TG ++    LDRE    Y L + A D G+P+ L
Sbjct: 1313 IVRYRLKMDTMGNF-----RKFSLDKETGELSLAASLDREQQMMYDLRIEAYDQGIPTPL 1367

Query: 562  SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT-DADV-----GLNGR 615
            S T D+ + V DVNDN P F  +  + N  E    GT   ++  T D D      G    
Sbjct: 1368 SSTVDLIVYVRDVNDNLPQFLLKEISLNFTEHMTPGTERIRLPDTVDQDYLDPLDGPAAS 1427

Query: 616  IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG--------GTPPQ 667
            +         E+G F +DP S  +   K LDRE  + + L   A +          T   
Sbjct: 1428 VVCYYIVHGNEDGHFGLDPVSHDLTVEKELDREKKSLYKLHIKATEECTNANLSLDTTSH 1487

Query: 668  SSTVI-VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
            S  ++   + I DIND+ PVFES   T  IS +S  G TI +++A D D+G N +V Y
Sbjct: 1488 SGNLLKATVYINDINDNSPVFESKIFTGGISTSSLFGATILQLQATDEDDGLNGLVRY 1545



 Score =  201 bits (491), Expect = 2e-49
 Identities = 193/678 (28%), Positives = 302/678 (44%), Gaps = 70/678 (10%)

Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS 164
           LDRE    YT+++  TD    + +    T +  + + D NDN P F      + V ED  
Sbjct: 127 LDREAREEYTLILTLTD--GRLGEGNFVTQSFLLLVEDINDNEPIFKPFASVLEVAED-- 182

Query: 165 VTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ-FSIDSLSGD--VSLVKTLDYEQVR 221
            +   ++  ++A D D GA   + Y I G + +   FSI + +G   V L + LDYE+  
Sbjct: 183 -SPPGILTTLEAVDKDEGAYGQVVYYIQGLSEENNVFSISTSNGKGVVRLARALDYERQH 241

Query: 222 SYRLVIRAQDGGSPSRSN--TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIG------ 273
            Y + + A D     R N  T  LL+ ++DV D  P F  +     +SE+ PIG      
Sbjct: 242 FYHINVLAVDRAIQGRINTGTAALLVRVKDVEDQPPEFLVTQPVVRISEDAPIGTEVASM 301

Query: 274 -YSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK- 331
            YS+  V+A D D G+N  + Y +++     N      ID   G + T  +LDRE     
Sbjct: 302 IYSLSTVKAVDGDRGINNRIIYGISN-----NGSELFEIDRLKGSLRTKQKLDREDSTNP 356

Query: 332 ----YQLLVTATDGG--DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
               + L V A +     P  S+T                F    YE E+ E+    T  
Sbjct: 357 INGAFILEVVAIEESKLQPAPSSTMEITVIVTDVNDEIPRFRSDGYECEIGENAQENTLA 416

Query: 386 VTLTAT-----DADEDNRLHYEITGGNTRGRFSITSQNGRGLIT----VAQP--LDFKQE 434
             +  +     D D+     + ++       F +  +      T    V  P  LD+++ 
Sbjct: 417 RFIDGSINEVFDYDQGKNGTFRLSLHPPSDIFEVIPKRAINEATFGLRVKDPSMLDYERV 476

Query: 435 RRYVLTV--SATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492
           R   LTV  S  +S GR+ TA +++ + D N+  P F    Y   V E+   GT +L + 
Sbjct: 477 RELSLTVVASEVESAGRTSTAQIRVVVLDQNDNFPEFSQPVYEIDVPENVTAGTVLLQLQ 536

Query: 493 ATDSDVGI--NAQITY-SLSSEISNEAVAHHDQQFVINPQTGAIT----TNKLLDRETMS 545
           ATDSD G+     + Y +L+  IS  +  H      ++P  G +T     + + DRE + 
Sbjct: 537 ATDSDSGLFGTEGVRYANLTGSIS--SFLH------LDPHAGTVTLMASESPVFDREIIQ 588

Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
            + L+V ARD G     +T  + ++V+DVNDN PVF Q+ Y   + E+A    S   V A
Sbjct: 589 KHYLSVEARDNGGRGNRNTVPLILNVLDVNDNAPVFVQKRYEVRLKENAFEFESPIVVEA 648

Query: 606 TDADV--GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE----SVATHDLKAVA 659
            D+D+    N  + Y L      +  F +D  +G +   +A+D E    S  + D + +A
Sbjct: 649 RDSDLEGSPNSAVEYRLIGAHHSD-YFHVDRRTGRLSVREAVDFERLESSGGSGDTRTIA 707

Query: 660 I-----DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
           +     DGG PP ++ V V + ++D+ND  PVF        I E++P G  +  + A D 
Sbjct: 708 LTIEAADGGEPPLTAQVEVTVYVQDVNDYAPVFLESQYAIVIPEDTPSGLPVLRVTAMDG 767

Query: 715 DEG-PNAVVHYSIKGGDD 731
           D   PN  V Y I+ G D
Sbjct: 768 DGSFPNNHVTYRIQQGGD 785



 Score =  192 bits (467), Expect = 2e-46
 Identities = 246/944 (26%), Positives = 391/944 (41%), Gaps = 105/944 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDI--GKNAEVEYTIELVTAD 68
            +NVLD ND++PVF  ++YE  ++E A    + + ++A D D+    N+ VEY   L+ A 
Sbjct: 612  LNVLDVNDNAPVFVQKRYEVRLKENAFEFESPIVVEARDSDLEGSPNSAVEY--RLIGAH 669

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARY-----TVLVKATDQA 123
                               D F +D R+G L  R ++D E++        T  +  T +A
Sbjct: 670  H-----------------SDYFHVDRRTGRLSVREAVDFERLESSGGSGDTRTIALTIEA 712

Query: 124  SPVSDR-LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
            +   +  L++   + V + D ND  P F E  Y + + ED + +  PV+ ++ A D D  
Sbjct: 713  ADGGEPPLTAQVEVTVYVQDVNDYAPVFLESQYAIVIPED-TPSGLPVL-RVTAMDGDGS 770

Query: 183  -ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVK--TLDYEQVR--------SYRLVIRAQD 231
              N+ + Y I  G    +F I + +G++S+    +LD   +         +Y L + A D
Sbjct: 771  FPNNHVTYRIQQGGDG-RFVIGASTGEISITHGASLDPNLLAPDALGSGSTYVLEVFATD 829

Query: 232  GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE 291
            GG+  +      L+N   V     R    L      E   + Y I R       EG   E
Sbjct: 830  GGNGDQQLQGSCLVNNTPVGTEVYR----LMATDPDEGAMLRYYIDR----SLSEGKTEE 881

Query: 292  LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVT----ATDGGDPPRS 347
                  D DY  +      ++  +G +  +  LDRE  A+ +L       A + GD  + 
Sbjct: 882  GALVKLD-DY--DFAAAFILNETNGLLKIAKLLDREKIAEIKLACVVEDVAAERGD--QM 936

Query: 348  ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGN 407
            A                 F    Y+  +AE+   G  V T+ A DAD++  + Y + G  
Sbjct: 937  ANTFLKITVLDENDNNPKFRKPFYKHSIAENSQYGVAVCTVVAEDADQNKTVKYSLEG-- 994

Query: 408  TRGRFSITSQNGR-GLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANN 464
             +G   +   +   G I V   +D ++      +V A D+G   R+    V + + D N+
Sbjct: 995  EKGVLELLHVDDETGEIVVRNRIDHEEYSWLNFSVRAADTGTPPRASFVEVFVQVLDEND 1054

Query: 465  YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524
              P F ++     V E+A +G  + ++ A D D G   +ITY L    S E       +F
Sbjct: 1055 NNPYFVDSVNDYYVSENASVGAEIAIILAKDLDSGDFGRITYILDRVSSKE-------KF 1107

Query: 525  VINPQTGAITTNKLLDRETMSGYLLTVTARDG------GVPSLSDTTDVEISVVDVNDNE 578
             I+P+ G +     LDRE  + Y+L V A D          S +    + I V+D NDN 
Sbjct: 1108 SIDPEKGILRVAGALDREETAEYMLAVEAWDNYPYGYLNGESRNAFKHILIHVLDDNDNV 1167

Query: 579  PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638
            PV ++    + I E   +   + ++ ATDAD   NG      D  D   G F I   S  
Sbjct: 1168 PVIQKPSGCSMITEYHNINDPIVKLRATDADDPTNGNGQLSFDIVD-PSGIFYIQQVSAQ 1226

Query: 639  IRT--NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF--ESDCLTF 694
                 ++   +     + L+ +  D G  P ++   V I + D ND  PVF   S   T 
Sbjct: 1227 YAEIYSRGPLKNLHGNYTLELIVSDLGGVPNTARETVDICVTDFNDHAPVFVVPSGNTTV 1286

Query: 695  YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN--SFSLETRQGSDKAELVTMV 752
             + EN+ +G    ++ A+D D G NA+V Y +K     N   FSL+   G    EL    
Sbjct: 1287 KVFENTTLGKPFFQVHAYDEDVGENAIVRYRLKMDTMGNFRKFSLDKETG----ELSLAA 1342

Query: 753  DLDYESPRKKYELVIRA----ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCF 808
             LD E  +  Y+L I A       PL + V + + V DVNDN P     +I  N  +   
Sbjct: 1343 SLDREQ-QMMYDLRIEAYDQGIPTPLSSTVDLIVYVRDVNDNLPQFLLKEISLNFTEHMT 1401

Query: 809  PVGPFGRVP-AYDADVTDKLQ--------YRILSGNNANLILLNETTGSMTLSPQLNTNV 859
            P     R+P   D D  D L         Y I+ GN      L+  +  +T+  +L+   
Sbjct: 1402 PGTERIRLPDTVDQDYLDPLDGPAASVVCYYIVHGNEDGHFGLDPVSHDLTVEKELDREK 1461

Query: 860  PKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDM 903
              L  + +  T+          LS+   +    L   TV +ND+
Sbjct: 1462 KSLYKLHIKATEECTN----ANLSLDTTSHSGNLLKATVYINDI 1501



 Score =  186 bits (454), Expect = 6e-45
 Identities = 199/755 (26%), Positives = 327/755 (43%), Gaps = 85/755 (11%)

Query: 13  VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72
           V D ND+ P+F+       V E +  G  + TL+A D+D G   +V Y I+ ++ +    
Sbjct: 160 VEDINDNEPIFKPFASVLEVAEDSPPGI-LTTLEAVDKDEGAYGQVVYYIQGLSEEN--- 215

Query: 73  EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132
                        V  +   +G+    L RA LD E+   Y + V A D+A  +  R+++
Sbjct: 216 ------------NVFSISTSNGKGVVRLARA-LDYERQHFYHINVLAVDRA--IQGRINT 260

Query: 133 -TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV-----IAKIKATDADVGANSA 186
            TA + V + D  D  P+F      V + ED  +          ++ +KA D D G N+ 
Sbjct: 261 GTAALLVRVKDVEDQPPEFLVTQPVVRISEDAPIGTEVASMIYSLSTVKAVDGDRGINNR 320

Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-------YRLVIRAQDGGSPSRSN 239
           I Y I    +++ F ID L G +   + LD E   +         +V   +    P+ S+
Sbjct: 321 IIYGISNNGSEL-FEIDRLKGSLRTKQKLDREDSTNPINGAFILEVVAIEESKLQPAPSS 379

Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRV------QAYDADEGVNAELT 293
           T ++ + + DVND  PRF +  ++  + EN     ++ R       + +D D+G N    
Sbjct: 380 TMEITVIVTDVNDEIPRFRSDGYECEIGENAQEN-TLARFIDGSINEVFDYDQGKNGTFR 438

Query: 294 YTMTDKDYTGNVDLPITIDPRSGW--VYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
            ++        V     I+  +    V     LD E   +  L V A++     R++TA 
Sbjct: 439 LSLHPPSDIFEVIPKRAINEATFGLRVKDPSMLDYERVRELSLTVVASEVESAGRTSTAQ 498

Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE----DNRLHYEITGGN 407
                         F    YE+++ E+   GT ++ L ATD+D        + Y    G+
Sbjct: 499 IRVVVLDQNDNFPEFSQPVYEIDVPENVTAGTVLLQLQATDSDSGLFGTEGVRYANLTGS 558

Query: 408 TRGRFSITSQNGRGLITVAQPLDFKQE--RRYVLTVSATDSGGRS--DTAMVQINITDAN 463
                 +    G   +  ++   F +E  +++ L+V A D+GGR   +T  + +N+ D N
Sbjct: 559 ISSFLHLDPHAGTVTLMASESPVFDREIIQKHYLSVEARDNGGRGNRNTVPLILNVLDVN 618

Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV--GINAQITYSLSSEISNEAVAHHD 521
           + APVF    Y   + E+A    + +VV A DSD+    N+ + Y L         AHH 
Sbjct: 619 DNAPVFVQKRYEVRLKENAFEFESPIVVEARDSDLEGSPNSAVEYRLIG-------AHHS 671

Query: 522 QQFVINPQTGAITTNKLLDRETM--SG-------YLLTVTARDGGVPSLSDTTDVEISVV 572
             F ++ +TG ++  + +D E +  SG         LT+ A DGG P L+   +V + V 
Sbjct: 672 DYFHVDRRTGRLSVREAVDFERLESSGGSGDTRTIALTIEAADGGEPPLTAQVEVTVYVQ 731

Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL-NGRIHYELDPKDREEGSFV 631
           DVND  PVF +  Y   I ED   G  V +V A D D    N  + Y +  +   +G FV
Sbjct: 732 DVNDYAPVFLESQYAIVIPEDTPSGLPVLRVTAMDGDGSFPNNHVTYRI--QQGGDGRFV 789

Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691
           I  ++G I         S+  + L   A+  G     ST ++ +   D  +     +  C
Sbjct: 790 IGASTGEISITHG---ASLDPNLLAPDALGSG-----STYVLEVFATDGGNGDQQLQGSC 841

Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
           L      N+P+GT +  + A DPDEG  A++ Y I
Sbjct: 842 LV----NNTPVGTEVYRLMATDPDEG--AMLRYYI 870



 Score =  179 bits (435), Expect = 1e-42
 Identities = 171/634 (26%), Positives = 278/634 (43%), Gaps = 55/634 (8%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I VLD ND++P F    Y+ S+ E +  G  V T+ A D D  +N  V+Y++E      
Sbjct: 942  KITVLDENDNNPKFRKPFYKHSIAENSQYGVAVCTVVAEDAD--QNKTVKYSLE------ 993

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                            V ++  +D  +G ++ R  +D E+ +     V+A D  +P    
Sbjct: 994  ------------GEKGVLELLHVDDETGEIVVRNRIDHEEYSWLNFSVRAADTGTPPR-- 1039

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             +S   + V ++D+NDN P F +      V E+ SV     IA I A D D G    I Y
Sbjct: 1040 -ASFVEVFVQVLDENDNNPYFVDSVNDYYVSENASV--GAEIAIILAKDLDSGDFGRITY 1096

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG------GSPSRSNTTQL 243
             +   +++ +FSID   G + +   LD E+   Y L + A D          SR+    +
Sbjct: 1097 ILDRVSSKEKFSIDPEKGILRVAGALDREETAEYMLAVEAWDNYPYGYLNGESRNAFKHI 1156

Query: 244  LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
            LI++ D NDN P          ++E   I   IV+++A DAD+  N     +    D +G
Sbjct: 1157 LIHVLDDNDNVPVIQKPSGCSMITEYHNINDPIVKLRATDADDPTNGNGQLSFDIVDPSG 1216

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
               +   +  +   +Y+ G L +     Y L +  +D G  P +A  T            
Sbjct: 1217 IFYIQ-QVSAQYAEIYSRGPL-KNLHGNYTLELIVSDLGGVPNTARETVDICVTDFNDHA 1274

Query: 364  XXFM--PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEI---TGGNTRGRFSITS 416
              F+   G   V++ E+   G P   + A D D  E+  + Y +   T GN R +FS+  
Sbjct: 1275 PVFVVPSGNTTVKVFENTTLGKPFFQVHAYDEDVGENAIVRYRLKMDTMGNFR-KFSLDK 1333

Query: 417  QNGRGLITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAP 473
            + G   +++A  LD +Q+  Y L + A D G     S T  + + + D N+  P F    
Sbjct: 1334 ETGE--LSLAASLDREQQMMYDLRIEAYDQGIPTPLSSTVDLIVYVRDVNDNLPQFLLKE 1391

Query: 474  YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
             + +  E    GT  + +  T     ++     + S         + D  F ++P +  +
Sbjct: 1392 ISLNFTEHMTPGTERIRLPDTVDQDYLDPLDGPAASVVCYYIVHGNEDGHFGLDPVSHDL 1451

Query: 534  TTNKLLDRETMSGYLLTVTARDGGV-PSLS-DTTD-------VEISVVDVNDNEPVFKQQ 584
            T  K LDRE  S Y L + A +     +LS DTT          + + D+NDN PVF+ +
Sbjct: 1452 TVEKELDREKKSLYKLHIKATEECTNANLSLDTTSHSGNLLKATVYINDINDNSPVFESK 1511

Query: 585  LYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618
            ++T  I   +L G ++ Q+ ATD D GLNG + Y
Sbjct: 1512 IFTGGISTSSLFGATILQLQATDEDDGLNGLVRY 1545



 Score =  175 bits (427), Expect = 1e-41
 Identities = 169/633 (26%), Positives = 288/633 (45%), Gaps = 56/633 (8%)

Query: 200  FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQLLINIRDVNDNAPRF 257
            F ++  +G + + K LD E++   +L    +D  +    +   T L I + D NDN P+F
Sbjct: 896  FILNETNGLLKIAKLLDREKIAEIKLACVVEDVAAERGDQMANTFLKITVLDENDNNPKF 955

Query: 258  YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317
                ++ S++EN   G ++  V A DAD+  N  + Y++  +   G ++L + +D  +G 
Sbjct: 956  RKPFYKHSIAENSQYGVAVCTVVAEDADQ--NKTVKYSLEGEK--GVLEL-LHVDDETGE 1010

Query: 318  VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377
            +    ++D E  +     V A D G PPR++                 F+    +  ++E
Sbjct: 1011 IVVRNRIDHEEYSWLNFSVRAADTGTPPRASFVEVFVQVLDENDNNPYFVDSVNDYYVSE 1070

Query: 378  DEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435
            +   G  +  + A D D  +  R+ Y +   +++ +FSI  +  +G++ VA  LD ++  
Sbjct: 1071 NASVGAEIAIILAKDLDSGDFGRITYILDRVSSKEKFSIDPE--KGILRVAGALDREETA 1128

Query: 436  RYVLTVSATDS------GGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
             Y+L V A D+       G S  A   + I++ D N+  PV +     + + E   I   
Sbjct: 1129 EYMLAVEAWDNYPYGYLNGESRNAFKHILIHVLDDNDNVPVIQKPSGCSMITEYHNINDP 1188

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
            ++ + ATD+D   N      LS +I + +   + QQ  ++ Q   I +   L +     Y
Sbjct: 1189 IVKLRATDADDPTNGN--GQLSFDIVDPSGIFYIQQ--VSAQYAEIYSRGPL-KNLHGNY 1243

Query: 548  LLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVF--KQQLYTANIMEDALVGTSVSQVG 604
             L +   D GGVP+ +  T V+I V D ND+ PVF       T  + E+  +G    QV 
Sbjct: 1244 TLELIVSDLGGVPNTARET-VDICVTDFNDHAPVFVVPSGNTTVKVFENTTLGKPFFQVH 1302

Query: 605  ATDADVGLNGRIHYELDPKDREE-GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
            A D DVG N  + Y L          F +D  +G +    +LDRE    +DL+  A D G
Sbjct: 1303 AYDEDVGENAIVRYRLKMDTMGNFRKFSLDKETGELSLAASLDREQQMMYDLRIEAYDQG 1362

Query: 664  TP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT-------TIGEIRAHDPD 715
             P P SSTV + + + D+ND+ P F    ++   +E+   GT       T+ +    DP 
Sbjct: 1363 IPTPLSSTVDLIVYVRDVNDNLPQFLLKEISLNFTEHMTPGTERIRLPDTVDQDYL-DPL 1421

Query: 716  EGPNA-VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---- 770
            +GP A VV Y I  G++   F L+        +L    +LD E  +  Y+L I+A     
Sbjct: 1422 DGPAASVVCYYIVHGNEDGHFGLDPVSH----DLTVEKELDREK-KSLYKLHIKATEECT 1476

Query: 771  --------SPPLWNDVRVEILVTDVNDNAPVMK 795
                    +    N ++  + + D+NDN+PV +
Sbjct: 1477 NANLSLDTTSHSGNLLKATVYINDINDNSPVFE 1509



 Score =  175 bits (426), Expect = 1e-41
 Identities = 191/692 (27%), Positives = 287/692 (41%), Gaps = 60/692 (8%)

Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ-LLINIRDVNDNAPRFYTSLFQESVS 267
           V L   LD E    Y L++   DG     +  TQ  L+ + D+NDN P F        V+
Sbjct: 121 VYLNHELDREAREEYTLILTLTDGRLGEGNFVTQSFLLLVEDINDNEPIFKPFASVLEVA 180

Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
           E+ P G  +  ++A D DEG   ++ Y +       NV   I+     G V  +  LD E
Sbjct: 181 EDSPPGI-LTTLEAVDKDEGAYGQVVYYIQGLSEENNV-FSISTSNGKGVVRLARALDYE 238

Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX--XFMPGQYEVELAEDEPPGTPV 385
            Q  Y + V A D     R  T T                F+  Q  V ++ED P GT V
Sbjct: 239 RQHFYHINVLAVDRAIQGRINTGTAALLVRVKDVEDQPPEFLVTQPVVRISEDAPIGTEV 298

Query: 386 V-------TLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436
                   T+ A D D   +NR+ Y I+   +   F I     +G +   Q LD +    
Sbjct: 299 ASMIYSLSTVKAVDGDRGINNRIIYGISNNGSE-LFEIDRL--KGSLRTKQKLDREDSTN 355

Query: 437 -----YVLTVSATDSG----GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
                ++L V A +        S T  + + +TD N+  P F +  Y   + E+A   T 
Sbjct: 356 PINGAFILEVVAIEESKLQPAPSSTMEITVIVTDVNDEIPRFRSDGYECEIGENAQENTL 415

Query: 488 VLVVSAT-----DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA-ITTNKLLDR 541
              +  +     D D G N   T+ LS    ++      ++ +     G  +    +LD 
Sbjct: 416 ARFIDGSINEVFDYDQGKNG--TFRLSLHPPSDIFEVIPKRAINEATFGLRVKDPSMLDY 473

Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
           E +    LTV A +      + T  + + V+D NDN P F Q +Y  ++ E+   GT + 
Sbjct: 474 ERVRELSLTVVASEVESAGRTSTAQIRVVVLDQNDNFPEFSQPVYEIDVPENVTAGTVLL 533

Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFV-IDPASGVI----RTNKALDRESVATHDLK 656
           Q+ ATD+D GL G              SF+ +DP +G +      +   DRE +  H L 
Sbjct: 534 QLQATDSDSGLFGTEGVRYANLTGSISSFLHLDPHAGTVTLMASESPVFDREIIQKHYLS 593

Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN-----SPIGTTIGEIRA 711
             A D G     +TV + + + D+ND+ PVF        + EN     SPI   + E R 
Sbjct: 594 VEARDNGGRGNRNTVPLILNVLDVNDNAPVFVQKRYEVRLKENAFEFESPI---VVEARD 650

Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS-DKAELVTMVDLDY---ESPRKKYELVI 767
            D +  PN+ V Y + G   S+ F ++ R G     E V    L+        +   L I
Sbjct: 651 SDLEGSPNSAVEYRLIGAHHSDYFHVDRRTGRLSVREAVDFERLESSGGSGDTRTIALTI 710

Query: 768 RAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD- 822
            AA    PPL   V V + V DVND APV  + Q      +D  P G P  RV A D D 
Sbjct: 711 EAADGGEPPLTAQVEVTVYVQDVNDYAPVFLESQYAIVIPEDT-PSGLPVLRVTAMDGDG 769

Query: 823 --VTDKLQYRILSGNNANLILLNETTGSMTLS 852
               + + YRI  G +   + +  +TG ++++
Sbjct: 770 SFPNNHVTYRIQQGGDGRFV-IGASTGEISIT 800



 Score =  167 bits (407), Expect = 3e-39
 Identities = 171/621 (27%), Positives = 274/621 (44%), Gaps = 53/621 (8%)

Query: 271 PIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA 330
           P+G  I R++ YDAD      LT+ +     +  + L       + +VY + +LDRE + 
Sbjct: 78  PVGTLIYRLRGYDAD---GDPLTFGVQKSADSHIIRLKQNTSSEA-FVYLNHELDREARE 133

Query: 331 KYQLLVTATDGG-DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389
           +Y L++T TDG        T +              F P    +E+AED PPG  + TL 
Sbjct: 134 EYTLILTLTDGRLGEGNFVTQSFLLLVEDINDNEPIFKPFASVLEVAEDSPPGI-LTTLE 192

Query: 390 ATDADED--NRLHYEITG-GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446
           A D DE    ++ Y I G       FSI++ NG+G++ +A+ LD++++  Y + V A D 
Sbjct: 193 AVDKDEGAYGQVVYYIQGLSEENNVFSISTSNGKGVVRLARALDYERQHFYHINVLAVDR 252

Query: 447 G--GR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL-------VVSATD 495
              GR  + TA + + + D  +  P F        + EDAPIGT V         V A D
Sbjct: 253 AIQGRINTGTAALLVRVKDVEDQPPEFLVTQPVVRISEDAPIGTEVASMIYSLSTVKAVD 312

Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS-----GYLLT 550
            D GIN +I Y +S+  S        + F I+   G++ T + LDRE  +      ++L 
Sbjct: 313 GDRGINNRIIYGISNNGS--------ELFEIDRLKGSLRTKQKLDREDSTNPINGAFILE 364

Query: 551 VTARDGG--VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT-- 606
           V A +     P+ S T ++ + V DVND  P F+   Y   I E+A   T    +  +  
Sbjct: 365 VVAIEESKLQPAPSSTMEITVIVTDVNDEIPRFRSDGYECEIGENAQENTLARFIDGSIN 424

Query: 607 ---DADVGLNGRIHYEL-DPKDREE--GSFVIDPASGVIRTN--KALDRESVATHDLKAV 658
              D D G NG     L  P D  E      I+ A+  +R      LD E V    L  V
Sbjct: 425 EVFDYDQGKNGTFRLSLHPPSDIFEVIPKRAINEATFGLRVKDPSMLDYERVRELSLTVV 484

Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG- 717
           A +  +  ++ST  + + + D ND+ P F        + EN   GT + +++A D D G 
Sbjct: 485 ASEVESAGRTSTAQIRVVVLDQNDNFPEFSQPVYEIDVPENVTAGTVLLQLQATDSDSGL 544

Query: 718 -PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN 776
                V Y+   G  S+   L+   G+           D E  +K Y  V    +    N
Sbjct: 545 FGTEGVRYANLTGSISSFLHLDPHAGTVTLMASESPVFDREIIQKHYLSVEARDNGGRGN 604

Query: 777 DVRVEIL--VTDVNDNAP--VMKDFQIIF--NNYKDCFPVGPFGRVPAYDADVTDKLQYR 830
              V ++  V DVNDNAP  V K +++    N ++   P+    R    +      ++YR
Sbjct: 605 RNTVPLILNVLDVNDNAPVFVQKRYEVRLKENAFEFESPIVVEARDSDLEGSPNSAVEYR 664

Query: 831 ILSGNNANLILLNETTGSMTL 851
           ++  ++++   ++  TG +++
Sbjct: 665 LIGAHHSDYFHVDRRTGRLSV 685



 Score =  151 bits (367), Expect = 2e-34
 Identities = 158/588 (26%), Positives = 251/588 (42%), Gaps = 79/588 (13%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + VLD ND++P F     +  V E AS G  +  + A D D G    + Y ++ V++   
Sbjct: 1047 VQVLDENDNNPYFVDSVNDYYVSENASVGAEIAIILAKDLDSGDFGRITYILDRVSS--- 1103

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS-PVSDR 129
                            ++ F ID   G L    +LDRE+ A Y + V+A D       + 
Sbjct: 1104 ----------------KEKFSIDPEKGILRVAGALDREETAEYMLAVEAWDNYPYGYLNG 1147

Query: 130  LSSTATIHV--NIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
             S  A  H+  +++DDNDN P   + +    + E  ++ D P++ K++ATDAD   N   
Sbjct: 1148 ESRNAFKHILIHVLDDNDNVPVIQKPSGCSMITEYHNIND-PIV-KLRATDADDPTN--- 1202

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVK-TLDYEQVRS----------YRLVIRAQD-GGSP 235
                  GN Q+ F I   SG   + + +  Y ++ S          Y L +   D GG P
Sbjct: 1203 ------GNGQLSFDIVDPSGIFYIQQVSAQYAEIYSRGPLKNLHGNYTLELIVSDLGGVP 1256

Query: 236  SRSNTTQLLINIRDVNDNAPRFYTSLFQESVS--ENVPIGYSIVRVQAYDADEGVNAELT 293
            + +  T + I + D ND+AP F       +V   EN  +G    +V AYD D G NA + 
Sbjct: 1257 NTARET-VDICVTDFNDHAPVFVVPSGNTTVKVFENTTLGKPFFQVHAYDEDVGENAIVR 1315

Query: 294  YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSATATX 352
            Y +   D  GN     ++D  +G +  +  LDRE Q  Y L + A D G P P S+T   
Sbjct: 1316 YRLK-MDTMGNFR-KFSLDKETGELSLAASLDREQQMMYDLRIEAYDQGIPTPLSSTVDL 1373

Query: 353  XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTAT---------DADEDNRLHYEI 403
                         F+  +  +   E   PGT  + L  T         D    + + Y I
Sbjct: 1374 IVYVRDVNDNLPQFLLKEISLNFTEHMTPGTERIRLPDTVDQDYLDPLDGPAASVVCYYI 1433

Query: 404  TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM--------- 454
              GN  G F +   +    +TV + LD +++  Y L + AT+    ++ ++         
Sbjct: 1434 VHGNEDGHFGLDPVSHD--LTVEKELDREKKSLYKLHIKATEECTNANLSLDTTSHSGNL 1491

Query: 455  --VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512
                + I D N+ +PVFE+  +T  +   +  G T+L + ATD D G+N  + Y    E+
Sbjct: 1492 LKATVYINDINDNSPVFESKIFTGGISTSSLFGATILQLQATDEDDGLNGLVRYYRHGEV 1551

Query: 513  SNEAVAHHD----QQFVINPQTGAITTNKLLDRETMSGYL-LTVTARD 555
                    D      F++   TG +  N    +++M GY   +V A D
Sbjct: 1552 RKTLAEGLDDLRSDPFLVEADTGQVLLN-FFPQKSMRGYFDFSVLAND 1598



 Score = 44.4 bits (100), Expect = 0.046
 Identities = 36/127 (28%), Positives = 61/127 (48%), Gaps = 10/127 (7%)

Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759
           +P+GT I  +R +D D  P   + + ++   DS+   L+ +  S +A +    +LD E+ 
Sbjct: 77  TPVGTLIYRLRGYDADGDP---LTFGVQKSADSHIIRLK-QNTSSEAFVYLNHELDREA- 131

Query: 760 RKKYELVIRAASPPLWNDVRVE----ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR 815
           R++Y L++      L     V     +LV D+NDN P+ K F  +    +D  P G    
Sbjct: 132 REEYTLILTLTDGRLGEGNFVTQSFLLLVEDINDNEPIFKPFASVLEVAEDS-PPGILTT 190

Query: 816 VPAYDAD 822
           + A D D
Sbjct: 191 LEAVDKD 197


>UniRef50_Q9VGG5 Cluster: Cadherin 87A precursor; n=2; Diptera|Rep:
            Cadherin 87A precursor - Drosophila melanogaster (Fruit
            fly)
          Length = 1975

 Score =  254 bits (621), Expect = 3e-65
 Identities = 230/775 (29%), Positives = 349/775 (45%), Gaps = 79/775 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEAS----VREGASSG-TTVLTLKATDQDIGKNAEVEYTIELV 65
            I++ +C+D+      ++ + +    V E    G   +L+++A  ++IG    V+YT  L+
Sbjct: 530  ISLANCHDNGESNRRERRDLNEDEHVEEDDGEGHLEMLSMEAATREIGTEPTVQYT--LI 587

Query: 66   TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125
            T        +                    +     +  LD E    Y +  KATD    
Sbjct: 588  TQAPEEQASSVPLPAPVPHAAPSGVPAATANDDKAPQTCLDYESETTYFLSYKATDDNGR 647

Query: 126  VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
             S   +S  ++ +++ D ND+ P      Y  SVDE   V D+P+I  +KA DAD    S
Sbjct: 648  GS---ASVVSLRISVTDANDSPPVCESPLYRASVDEGAVVFDSPLI--VKARDADT--MS 700

Query: 186  AIRYAIIGGN-TQMQFSIDSLSGDVSLVK--TLDYEQVRSYRLV--IRAQDGGSPSRSNT 240
             I Y I G    +  F ID  +G + +    TLD   + S +L+  + A DG   +    
Sbjct: 701  RISYRIRGSEQVESIFDIDRETGQIIIRPNATLDVTNLNSDQLIFAVEANDGLFTAHCGV 760

Query: 241  TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
                I +RDVN++ P F    +   V EN  IG S+ RV A D D G NAEL Y +    
Sbjct: 761  N---ITVRDVNNHVPNFEQQSYSAVVEENSEIGTSVERVHATDLDTGKNAELRYRIQQ-- 815

Query: 301  YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
              G+ D    I   +G V+ S +LD + +  YQL + A+D G P  + TAT         
Sbjct: 816  --GSFD-DFGIVETTGEVFVSRKLDFDRRNTYQLQIQASDQGTPSLTGTATLTINVQNSN 872

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHY----EITGGNTRGR--- 411
                 F+P     E+  D PPG  V TL A D D    N L +    +IT  +  G+   
Sbjct: 873  DKDPYFVPATQHAEVRADAPPGQLVYTLIALDPDVANHNALEFAGTDDITAIDKEGKELP 932

Query: 412  --------FSITSQNGRGLITVAQPLD---FKQERRYVLTVSATDSGGRSDTAMVQINIT 460
                    F I S+NG+  ++V + LD   F   R  VL   +T    +    ++ I I 
Sbjct: 933  HYDQFKEYFKI-SRNGK--VSVNKQLDRNLFAVMRINVLVTDSTAPNVQQGRGLLIIQII 989

Query: 461  DANNYAPVFENAPYTAS-------VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513
            D N   P F NAP++         + E+ P+GT +  + A D D            S I 
Sbjct: 990  DVNKNPPRF-NAPWSVEQPQIKLQMVEEQPVGTVLTTLQANDED------------SSIG 1036

Query: 514  NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
               ++ +D  F IN  +G I T   LD E +      VT  D GVP+L+ T DV + +++
Sbjct: 1037 EFNISDNDY-FAINQTSGMIYTIARLDYEVVKEVKFQVTVSDTGVPALTATADVVVDIIN 1095

Query: 574  VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633
            +NDN+P F Q  Y  N+ E++  GT   +V A D DVG+ G I Y L  ++ +   F ID
Sbjct: 1096 LNDNDPKFSQSDYYFNVTENSPRGTVAGKVEAHDGDVGVFGEITYTLIGENNK--YFSID 1153

Query: 634  PASG--VIRTNKALDRESVATHDLKAVAID--GGTPPQSSTVIVHIKIEDINDSPPVFES 689
              +G  ++  +  LDRE +    L  VA D       +S+T  +HI I D+ND+ PVF  
Sbjct: 1154 AYTGNVMVANSSILDREQIKELTLSVVAQDKAPAAVQKSATATIHINILDVNDNAPVFTR 1213

Query: 690  DCLTFYISENSPI--GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
            D     ++EN+       + +++A D DEG    V Y I  G++   F L+ + G
Sbjct: 1214 DVYNSTVAENAAYQPPAALLQVQAIDQDEGLYGDVRYIITAGNEMGLFKLDAQSG 1268



 Score =  242 bits (593), Expect = 8e-62
 Identities = 255/901 (28%), Positives = 398/901 (44%), Gaps = 107/901 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D N+H P FE Q Y A V E +  GT+V  + ATD D GKNAE+ Y I+  + D  
Sbjct: 762  ITVRDVNNHVPNFEQQSYSAVVEENSEIGTSVERVHATDLDTGKNAELRYRIQQGSFDD- 820

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                               F I   +G +     LD ++   Y + ++A+DQ +P    L
Sbjct: 821  -------------------FGIVETTGEVFVSRKLDFDRRNTYQLQIQASDQGTP---SL 858

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            + TAT+ +N+ + ND  P F   T    V  D       ++  + A D DV  ++A+ +A
Sbjct: 859  TGTATLTINVQNSNDKDPYFVPATQHAEVRAD--APPGQLVYTLIALDPDVANHNALEFA 916

Query: 191  IIGGNTQMQ---------------FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP 235
                 T +                F I S +G VS+ K LD       R+ +   D  +P
Sbjct: 917  GTDDITAIDKEGKELPHYDQFKEYFKI-SRNGKVSVNKQLDRNLFAVMRINVLVTDSTAP 975

Query: 236  S-RSNTTQLLINIRDVNDNAPRFYT--SLFQESVS----ENVPIGYSIVRVQAYDADEGV 288
            + +     L+I I DVN N PRF    S+ Q  +     E  P+G  +  +QA D D  +
Sbjct: 976  NVQQGRGLLIIQIIDVNKNPPRFNAPWSVEQPQIKLQMVEEQPVGTVLTTLQANDEDSSI 1035

Query: 289  NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348
                 + ++D DY         I+  SG +YT  +LD E   + +  VT +D G P  +A
Sbjct: 1036 GE---FNISDNDY-------FAINQTSGMIYTIARLDYEVVKEVKFQVTVSDTGVPALTA 1085

Query: 349  TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGG 406
            TA               F    Y   + E+ P GT    + A D D      + Y + G 
Sbjct: 1086 TADVVVDIINLNDNDPKFSQSDYYFNVTENSPRGTVAGKVEAHDGDVGVFGEITYTLIGE 1145

Query: 407  NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG----RSDTAMVQINITDA 462
            N +  FSI +  G  ++  +  LD +Q +   L+V A D       +S TA + INI D 
Sbjct: 1146 NNK-YFSIDAYTGNVMVANSSILDREQIKELTLSVVAQDKAPAAVQKSATATIHINILDV 1204

Query: 463  NNYAPVFENAPYTASVFEDAPIG--TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520
            N+ APVF    Y ++V E+A       +L V A D D G+   + Y +++   NE     
Sbjct: 1205 NDNAPVFTRDVYNSTVAENAAYQPPAALLQVQAIDQDEGLYGDVRYIITA--GNEMGL-- 1260

Query: 521  DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEP 579
               F ++ Q+G +   + L  +    Y LT++ARD  G  ++  TT   I+V+ VN ++P
Sbjct: 1261 ---FKLDAQSGIVYPAQSLSGKH-GAYELTISARDTQGSGTMESTTKAIITVLRVNRHKP 1316

Query: 580  VFK-QQLYTANI-MEDALVGTS--VSQVGATDADVGLNGRIHYELDPKDREE---GSFVI 632
             F    L  A I +   +V     +  V A D D   NG++ Y L   +R E   G F I
Sbjct: 1317 EFVIPALSNATIEIPGDIVQPDYLLLTVRAMDNDTEENGKVSYHLQVNNRNEQQTGEFKI 1376

Query: 633  DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF--ESD 690
            D  +G +R    L+R++ A +D+  VA D G PP  S  ++ + I D N++ P F   S+
Sbjct: 1377 DEVTGELRAKTQLNRKNRANYDIILVARDAGNPPFESLRLLSVSIVDANENRPEFPDASN 1436

Query: 691  CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF------SLETRQGSD 744
                 I+ENS     IG I+A    +    + +Y + G +D   +       + T +  D
Sbjct: 1437 PYKVSINENSGRDVKIGHIQAASRSKHNRDIFYYMLLGNEDGAFYVDKLTGDIYTNKSLD 1496

Query: 745  KAE-------LVTMVDLD-YESPRKKYELVIRAASPPLWNDV-RVEILVTDVNDNAPVMK 795
            + E       ++  +  D + S  ++    I+  +    N V +V I V DVNDN PV +
Sbjct: 1497 REETDVYTLYILASIKADLHISEEERASFSIKTLNRD--NTVAKVAITVLDVNDNPPVFE 1554

Query: 796  DFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLS 852
               I +        +G     V A DAD     K+++ I++ +N       ++TGS+  S
Sbjct: 1555 K-PIYYAGVNANAKMGAAITLVNATDADQGKNAKIEFMIVA-SNLYKFGATKSTGSIVPS 1612

Query: 853  P 853
            P
Sbjct: 1613 P 1613



 Score =  223 bits (546), Expect = 4e-56
 Identities = 237/901 (26%), Positives = 409/901 (45%), Gaps = 92/901 (10%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I+V D ND  PV E   Y ASV EGA    + L +KA D D    + + Y I       
Sbjct: 656  RISVTDANDSPPVCESPLYRASVDEGAVVFDSPLIVKARDADT--MSRISYRIR------ 707

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR--ASLDREKVARYTVLVKATDQASPVS 127
                            V+ +F ID  +G ++ R  A+LD   +    ++      A   +
Sbjct: 708  ------------GSEQVESIFDIDRETGQIIIRPNATLDVTNLNSDQLIF-----AVEAN 750

Query: 128  DRL-SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
            D L ++   +++ + D N++ P F +++Y+  V+E+  +  +  + ++ ATD D G N+ 
Sbjct: 751  DGLFTAHCGVNITVRDVNNHVPNFEQQSYSAVVEENSEIGTS--VERVHATDLDTGKNAE 808

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            +RY I  G+    F I   +G+V + + LD+++  +Y+L I+A D G+PS + T  L IN
Sbjct: 809  LRYRIQQGSFD-DFGIVETTGEVFVSRKLDFDRRNTYQLQIQASDQGTPSLTGTATLTIN 867

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK----DYT 302
            +++ ND  P F  +     V  + P G  +  + A D D   +  L +  TD     D  
Sbjct: 868  VQNSNDKDPYFVPATQHAEVRADAPPGQLVYTLIALDPDVANHNALEFAGTDDITAIDKE 927

Query: 303  GNVDLPITID-------PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP-RSATATXXX 354
            G  +LP            R+G V  + QLDR   A  ++ V  TD   P  +        
Sbjct: 928  GK-ELPHYDQFKEYFKISRNGKVSVNKQLDRNLFAVMRINVLVTDSTAPNVQQGRGLLII 986

Query: 355  XXXXXXXXXXXFMPG------QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT 408
                       F         Q ++++ E++P GT + TL A D D      + I+  + 
Sbjct: 987  QIIDVNKNPPRFNAPWSVEQPQIKLQMVEEQPVGTVLTTLQANDEDSSIG-EFNISDNDY 1045

Query: 409  RGRFSITSQNGRGLITVAQPLDFK--QERRYVLTVSATDSGGRSDTAMVQINITDANNYA 466
               F+I   +G  + T+A+ LD++  +E ++ +TVS T     + TA V ++I + N+  
Sbjct: 1046 ---FAINQTSGM-IYTIAR-LDYEVVKEVKFQVTVSDTGVPALTATADVVVDIINLNDND 1100

Query: 467  PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
            P F  + Y  +V E++P GT    V A D DVG+  +ITY+L  E        +++ F I
Sbjct: 1101 PKFSQSDYYFNVTENSPRGTVAGKVEAHDGDVGVFGEITYTLIGE--------NNKYFSI 1152

Query: 527  NPQTG--AITTNKLLDRETMSGYLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFK 582
            +  TG   +  + +LDRE +    L+V A+D    ++  S T  + I+++DVNDN PVF 
Sbjct: 1153 DAYTGNVMVANSSILDREQIKELTLSVVAQDKAPAAVQKSATATIHINILDVNDNAPVFT 1212

Query: 583  QQLYTANIMEDALVG--TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640
            + +Y + + E+A      ++ QV A D D GL G + Y +   + E G F +D  SG++ 
Sbjct: 1213 RDVYNSTVAENAAYQPPAALLQVQAIDQDEGLYGDVRYIITAGN-EMGLFKLDAQSGIVY 1271

Query: 641  TNKALDRESVATHDLKAVAIDG-GTPPQSSTVIVHIKIEDINDSPPVFESDCL---TFYI 696
              ++L  +  A ++L   A D  G+    ST    I +  +N   P F    L   T  I
Sbjct: 1272 PAQSLSGKHGA-YELTISARDTQGSGTMESTTKAIITVLRVNRHKPEFVIPALSNATIEI 1330

Query: 697  -SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755
              +       +  +RA D D   N  V Y ++  + +   + E +      EL     L+
Sbjct: 1331 PGDIVQPDYLLLTVRAMDNDTEENGKVSYHLQVNNRNEQQTGEFKIDEVTGELRAKTQLN 1390

Query: 756  YESPRKKYELVI--RAASPPLWNDVRV-EILVTDVNDNAPVMKDFQIIFNNYKDCFPVG- 811
             ++ R  Y++++  R A  P +  +R+  + + D N+N P   +F    N YK       
Sbjct: 1391 RKN-RANYDIILVARDAGNPPFESLRLLSVSIVDANENRP---EFPDASNPYKVSINENS 1446

Query: 812  ----PFGRVPAYDADVTDK-LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATME 866
                  G + A      ++ + Y +L GN      +++ TG +  +  L+     + T+ 
Sbjct: 1447 GRDVKIGHIQAASRSKHNRDIFYYMLLGNEDGAFYVDKLTGDIYTNKSLDREETDVYTLY 1506

Query: 867  V 867
            +
Sbjct: 1507 I 1507



 Score =  198 bits (484), Expect = 1e-48
 Identities = 194/659 (29%), Positives = 298/659 (45%), Gaps = 69/659 (10%)

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
            TL   D             D F I+  SG + T A LD E V      V  +D   P   
Sbjct: 1025 TLQANDEDSSIGEFNISDNDYFAINQTSGMIYTIARLDYEVVKEVKFQVTVSDTGVPA-- 1082

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             L++TA + V+II+ NDN P+FS+  Y  +V E+       V  K++A D DVG    I 
Sbjct: 1083 -LTATADVVVDIINLNDNDPKFSQSDYYFNVTENSP--RGTVAGKVEAHDGDVGVFGEIT 1139

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPS--RSNTTQLL 244
            Y +IG N +  FSID+ +G+V +  +  LD EQ++   L + AQD    +  +S T  + 
Sbjct: 1140 YTLIGENNKY-FSIDAYTGNVMVANSSILDREQIKELTLSVVAQDKAPAAVQKSATATIH 1198

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIG--YSIVRVQAYDADEGVNAELTYTMTDKDYT 302
            INI DVNDNAP F   ++  +V+EN       ++++VQA D DEG+  ++ Y +T     
Sbjct: 1199 INILDVNDNAPVFTRDVYNSTVAENAAYQPPAALLQVQAIDQDEGLYGDVRYIIT----A 1254

Query: 303  GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD--GGDPPRSATATXXXXXXXXX 360
            GN      +D +SG VY +  L  +  A Y+L ++A D  G     S T           
Sbjct: 1255 GNEMGLFKLDAQSGIVYPAQSLSGKHGA-YELTISARDTQGSGTMESTTKAIITVLRVNR 1313

Query: 361  XXXXXFMPG--QYEVELAED-EPPGTPVVTLTATDAD--EDNRLHYEITGGNTR----GR 411
                  +P      +E+  D   P   ++T+ A D D  E+ ++ Y +   N      G 
Sbjct: 1314 HKPEFVIPALSNATIEIPGDIVQPDYLLLTVRAMDNDTEENGKVSYHLQVNNRNEQQTGE 1373

Query: 412  FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVF 469
            F I    G   +     L+ K    Y + + A D+G        ++ ++I DAN   P F
Sbjct: 1374 FKIDEVTGE--LRAKTQLNRKNRANYDIILVARDAGNPPFESLRLLSVSIVDANENRPEF 1431

Query: 470  ENA--PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527
             +A  PY  S+ E++     +  + A       N  I Y +   + NE     D  F ++
Sbjct: 1432 PDASNPYKVSINENSGRDVKIGHIQAASRSKH-NRDIFYYML--LGNE-----DGAFYVD 1483

Query: 528  PQTGAITTNKLLDRETMSGYLLTVTAR-------------DGGVPSLS-DTT--DVEISV 571
              TG I TNK LDRE    Y L + A                 + +L+ D T   V I+V
Sbjct: 1484 KLTGDIYTNKSLDREETDVYTLYILASIKADLHISEEERASFSIKTLNRDNTVAKVAITV 1543

Query: 572  VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD------- 624
            +DVNDN PVF++ +Y A +  +A +G +++ V ATDAD G N +I + +   +       
Sbjct: 1544 LDVNDNPPVFEKPIYYAGVNANAKMGAAITLVNATDADQGKNAKIEFMIVASNLYKFGAT 1603

Query: 625  REEGSFVIDP----ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679
            +  GS V  P      G I  N  +   +    +L+ VA +   P  S++  V+I + D
Sbjct: 1604 KSTGSIVPSPFAISQDGRISANTIMAEYNQDRFELEIVARELEQPQSSASTKVNIWVFD 1662



 Score =  187 bits (455), Expect = 4e-45
 Identities = 213/808 (26%), Positives = 344/808 (42%), Gaps = 81/808 (10%)

Query: 13  VLDCNDHSPVFEMQQYEASVREGASSGTTVL-TLKATDQDI-GKNAEVEYTIELVTADTL 70
           +LD ND+ P F+   YEA V E A+ GTT+   +   D+DI G++ +++           
Sbjct: 122 ILDLNDNPPEFQNTPYEADVNEDAAVGTTIFDKITVKDRDIVGESLDLK-----CLPQQQ 176

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           +PE               +        A++   +L+  +   Y   ++ATD         
Sbjct: 177 SPEACRKFRLHIIKRDATIL-----EAAVVLNDTLNYNQRMVYHFQIEATDGPH------ 225

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +  T    + D  D  P F     TV +DED  +  N ++  + A D D G    I Y 
Sbjct: 226 KTQTTFEARVKDVQDKPPVFQGSLSTV-IDEDSPI--NTLVLTVHARDGDTGEPRKIVYD 282

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS----YRLVIRAQD--GGSPS----RSNT 240
            +  N    F +D+ +G++   K LD E +        LVIRA++   G PS     S T
Sbjct: 283 -LRTNPNDYFLLDAQTGELRTAKPLDREALEDSTGIISLVIRARELVNGVPSDDPLTSAT 341

Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSI-VRVQAYDADEGVNAELTYTMTDK 299
            +  + IRDVND+ P F    +  S+ EN   G  + + +   DAD G+N++    + D 
Sbjct: 342 AKATVTIRDVNDSPPVFNHKEYSVSLLENTLPGTPLALDMSVSDADVGINSKFALRLDDV 401

Query: 300 DYTGNVDLP-ITIDPRSGWVYTSGQLDRE--TQAKYQLLVTATDGGDPPR-SATATXXXX 355
               +V+   +T   +      +G LD E   Q K+ +LV A +    PR S+TAT    
Sbjct: 402 SGVFDVEPKLVTGYSQVNIRVANGTLDYENPNQRKFIVLVVAEETDTNPRLSSTATITVS 461

Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE----DNRLHYEITGGNTRGR 411
                     F    Y   ++E   PG  + T+TA D D     D+ + Y ++G      
Sbjct: 462 VLDANDNKPVFEQESYSASVSEAALPGQYIATITARDVDSGSYGDSGIRYSLSGTGAE-L 520

Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN 471
           F +  Q   G+I++A   D  +  R        D     D         D   +  +   
Sbjct: 521 FHVNEQT--GVISLANCHDNGESNRRERRDLNEDEHVEED---------DGEGHLEMLSM 569

Query: 472 APYTASVFEDAPIGTTVLVVSATD--SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
              T  +  +  +  T++  +  +  S V + A + ++  S +   A A+ D+     PQ
Sbjct: 570 EAATREIGTEPTVQYTLITQAPEEQASSVPLPAPVPHAAPSGVP-AATANDDKA----PQ 624

Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589
           T        LD E+ + Y L+  A D      +    + ISV D ND+ PV +  LY A+
Sbjct: 625 T-------CLDYESETTYFLSYKATDDNGRGSASVVSLRISVTDANDSPPVCESPLYRAS 677

Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG--VIRTNKALDR 647
           + E A+V  S   V A DAD     RI Y +   ++ E  F ID  +G  +IR N  LD 
Sbjct: 678 VDEGAVVFDSPLIVKARDADT--MSRISYRIRGSEQVESIFDIDRETGQIIIRPNATLDV 735

Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
            ++ +  L   A++      ++   V+I + D+N+  P FE    +  + ENS IGT++ 
Sbjct: 736 TNLNSDQL-IFAVEANDGLFTAHCGVNITVRDVNNHVPNFEQQSYSAVVEENSEIGTSVE 794

Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
            + A D D G NA + Y I+ G   +   +ET       E+     LD++  R  Y+L I
Sbjct: 795 RVHATDLDTGKNAELRYRIQQGSFDDFGIVET-----TGEVFVSRKLDFDR-RNTYQLQI 848

Query: 768 RAA---SPPLWNDVRVEILVTDVNDNAP 792
           +A+   +P L     + I V + ND  P
Sbjct: 849 QASDQGTPSLTGTATLTINVQNSNDKDP 876



 Score =  185 bits (450), Expect = 2e-44
 Identities = 172/659 (26%), Positives = 289/659 (43%), Gaps = 43/659 (6%)

Query: 215  LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY 274
            LDYE   +Y L  +A D      ++   L I++ D ND+ P   + L++ SV E   +  
Sbjct: 627  LDYESETTYFLSYKATDDNGRGSASVVSLRISVTDANDSPPVCESPLYRASVDEGAVVFD 686

Query: 275  SIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE-TQAKYQ 333
            S + V+A DAD    + ++Y +   +   ++     ID  +G +        + T     
Sbjct: 687  SPLIVKARDAD--TMSRISYRIRGSEQVESI---FDIDRETGQIIIRPNATLDVTNLNSD 741

Query: 334  LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393
             L+ A +  D   +A                 F    Y   + E+   GT V  + ATD 
Sbjct: 742  QLIFAVEANDGLFTAHCGVNITVRDVNNHVPNFEQQSYSAVVEENSEIGTSVERVHATDL 801

Query: 394  D--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS- 450
            D  ++  L Y I  G+    F I    G   + V++ LDF +   Y L + A+D G  S 
Sbjct: 802  DTGKNAELRYRIQQGSFDD-FGIVETTGE--VFVSRKLDFDRRNTYQLQIQASDQGTPSL 858

Query: 451  -DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509
              TA + IN+ ++N+  P F  A   A V  DAP G  V  + A D DV  +  + ++ +
Sbjct: 859  TGTATLTINVQNSNDKDPYFVPATQHAEVRADAPPGQLVYTLIALDPDVANHNALEFAGT 918

Query: 510  SEIS-----NEAVAHHDQ--QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
             +I+      + + H+DQ  ++    + G ++ NK LDR   +   + V   D   P++ 
Sbjct: 919  DDITAIDKEGKELPHYDQFKEYFKISRNGKVSVNKQLDRNLFAVMRINVLVTDSTAPNVQ 978

Query: 563  DTTDVEI-SVVDVNDNEPVF------KQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615
                + I  ++DVN N P F      +Q      ++E+  VGT ++ + A D D  +   
Sbjct: 979  QGRGLLIIQIIDVNKNPPRFNAPWSVEQPQIKLQMVEEQPVGTVLTTLQANDEDSSIG-- 1036

Query: 616  IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675
               E +  D +   F I+  SG+I T   LD E V     +    D G P  ++T  V +
Sbjct: 1037 ---EFNISDNDY--FAINQTSGMIYTIARLDYEVVKEVKFQVTVSDTGVPALTATADVVV 1091

Query: 676  KIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735
             I ++ND+ P F      F ++ENSP GT  G++ AHD D G    + Y++ G +++  F
Sbjct: 1092 DIINLNDNDPKFSQSDYYFNVTENSPRGTVAGKVEAHDGDVGVFGEITYTLIG-ENNKYF 1150

Query: 736  SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND---VRVEILVTDVNDNAP 792
            S++   G+      +++D + +       +V +  +P          + I + DVNDNAP
Sbjct: 1151 SIDAYTGNVMVANSSILDRE-QIKELTLSVVAQDKAPAAVQKSATATIHINILDVNDNAP 1209

Query: 793  VM-KD-FQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTG 847
            V  +D +           P     +V A D D  +   ++Y I +GN   L  L+  +G
Sbjct: 1210 VFTRDVYNSTVAENAAYQPPAALLQVQAIDQDEGLYGDVRYIITAGNEMGLFKLDAQSG 1268



 Score =  184 bits (449), Expect = 2e-44
 Identities = 160/596 (26%), Positives = 262/596 (43%), Gaps = 57/596 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +++++ ND+ P F    Y  +V E +  GT    ++A D D+G   E+ YT+        
Sbjct: 1091 VDIINLNDNDPKFSQSDYYFNVTENSPRGTVAGKVEAHDGDVGVFGEITYTL-------- 1142

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS--LDREKVARYTVLVKATDQASPVSD 128
                               F ID  +G ++   S  LDRE++   T+ V A D+A P + 
Sbjct: 1143 ------------IGENNKYFSIDAYTGNVMVANSSILDREQIKELTLSVVAQDKA-PAAV 1189

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            + S+TATIH+NI+D NDN P F+   Y  +V E+ +      + +++A D D G    +R
Sbjct: 1190 QKSATATIHINILDVNDNAPVFTRDVYNSTVAENAAYQPPAALLQVQAIDQDEGLYGDVR 1249

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG-GSPSRSNTTQLLINI 247
            Y I  GN    F +D+ SG V   ++L  +   +Y L I A+D  GS +  +TT+ +I +
Sbjct: 1250 YIITAGNEMGLFKLDAQSGIVYPAQSLSGKH-GAYELTISARDTQGSGTMESTTKAIITV 1308

Query: 248  RDVNDNAPRFYTSLFQESVSEN----VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
              VN + P F       +  E     V   Y ++ V+A D D   N +++Y +   +   
Sbjct: 1309 LRVNRHKPEFVIPALSNATIEIPGDIVQPDYLLLTVRAMDNDTEENGKVSYHLQVNNRNE 1368

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
                   ID  +G +    QL+R+ +A Y +++ A D G+PP  +               
Sbjct: 1369 QQTGEFKIDEVTGELRAKTQLNRKNRANYDIILVARDAGNPPFESLRLLSVSIVDANENR 1428

Query: 364  XXFMPGQ--YEVELAEDEPPGTPVVTLTATDADEDNR-LHYEITGGNTRGRFSITSQNGR 420
              F      Y+V + E+      +  + A    + NR + Y +  GN  G F +    G 
Sbjct: 1429 PEFPDASNPYKVSINENSGRDVKIGHIQAASRSKHNRDIFYYMLLGNEDGAFYVDKLTGD 1488

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSG-----------------GRSDT-AMVQINITDA 462
              I   + LD ++   Y L + A+                     R +T A V I + D 
Sbjct: 1489 --IYTNKSLDREETDVYTLYILASIKADLHISEEERASFSIKTLNRDNTVAKVAITVLDV 1546

Query: 463  NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL-SSEISNEAVAHHD 521
            N+  PVFE   Y A V  +A +G  + +V+ATD+D G NA+I + + +S +         
Sbjct: 1547 NDNPPVFEKPIYYAGVNANAKMGAAITLVNATDADQGKNAKIEFMIVASNLYKFGATKST 1606

Query: 522  QQFVINP----QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
               V +P    Q G I+ N ++       + L + AR+   P  S +T V I V D
Sbjct: 1607 GSIVPSPFAISQDGRISANTIMAEYNQDRFELEIVARELEQPQSSASTKVNIWVFD 1662



 Score =  146 bits (353), Expect = 1e-32
 Identities = 149/513 (29%), Positives = 232/513 (45%), Gaps = 50/513 (9%)

Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434
           L E+   GT V  L A D  E + + Y   G +    FS+   +G   IT+ +PLD +++
Sbjct: 36  LYENVTVGTVVFRLEAYDP-EGSPVTYGAIGAD---HFSVDPVSGN--ITLIKPLDREEK 89

Query: 435 RRYVLTVSATD----SGGRSDTAMVQINIT----DANNYAPVFENAPYTASVFEDAPIGT 486
                 VS  D     G      +V++ IT    D N+  P F+N PY A V EDA +GT
Sbjct: 90  DTLKFLVSIRDRVDPEGESERDNVVEVPITFIILDLNDNPPEFQNTPYEADVNEDAAVGT 149

Query: 487 TVL-VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT---GAITTNKLLDRE 542
           T+   ++  D D+   +     L  + S EA        +    T    A+  N  L+  
Sbjct: 150 TIFDKITVKDRDIVGESLDLKCLPQQQSPEACRKFRLHIIKRDATILEAAVVLNDTLNYN 209

Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
               Y   + A DG  P  + TT  E  V DV D  PVF+  L T  I ED+ + T V  
Sbjct: 210 QRMVYHFQIEATDG--PHKTQTT-FEARVKDVQDKPPVFQGSLSTV-IDEDSPINTLVLT 265

Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES------VATHDLK 656
           V A D D G   +I Y+L  +      F++D  +G +RT K LDRE+      + +  ++
Sbjct: 266 VHARDGDTGEPRKIVYDL--RTNPNDYFLLDAQTGELRTAKPLDREALEDSTGIISLVIR 323

Query: 657 AVAIDGGTPPQ----SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG-EIRA 711
           A  +  G P      S+T    + I D+NDSPPVF     +  + EN+  GT +  ++  
Sbjct: 324 ARELVNGVPSDDPLTSATAKATVTIRDVNDSPPVFNHKEYSVSLLENTLPGTPLALDMSV 383

Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAEL---VTMVDLDYESPRKKYELVIR 768
            D D G N+   ++++  D S  F +E +  +  +++   V    LDYE+P ++  +V+ 
Sbjct: 384 SDADVGINS--KFALRLDDVSGVFDVEPKLVTGYSQVNIRVANGTLDYENPNQRKFIVLV 441

Query: 769 AA-----SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV 823
            A     +P L +   + + V D NDN PV +      +  +   P      + A D D 
Sbjct: 442 VAEETDTNPRLSSTATITVSVLDANDNKPVFEQESYSASVSEAALPGQYIATITARDVDS 501

Query: 824 ----TDKLQYRILSGNNANLILLNETTGSMTLS 852
                  ++Y  LSG  A L  +NE TG ++L+
Sbjct: 502 GSYGDSGIRYS-LSGTGAELFHVNEQTGVISLA 533



 Score =  144 bits (348), Expect = 4e-32
 Identities = 192/782 (24%), Positives = 323/782 (41%), Gaps = 85/782 (10%)

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
           P F++    + + E+++V    V+ +++A D +    S + Y  IG +    FS+D +SG
Sbjct: 25  PVFTQTLNNIILYENVTV--GTVVFRLEAYDPE---GSPVTYGAIGAD---HFSVDPVSG 76

Query: 208 DVSLVKTLDYEQVRSYRLVIRAQD----GGSPSRSNTTQLLIN--IRDVNDNAPRFYTSL 261
           +++L+K LD E+  + + ++  +D     G   R N  ++ I   I D+NDN P F  + 
Sbjct: 77  NITLIKPLDREEKDTLKFLVSIRDRVDPEGESERDNVVEVPITFIILDLNDNPPEFQNTP 136

Query: 262 FQESVSENVPIGYSIV-RVQAYDAD-EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319
           ++  V+E+  +G +I  ++   D D  G + +L      +         + I  R   + 
Sbjct: 137 YEADVNEDAAVGTTIFDKITVKDRDIVGESLDLKCLPQQQSPEACRKFRLHIIKRDATIL 196

Query: 320 TSGQLDRET-----QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374
            +  +  +T     +  Y   + ATDG   P     T              F  G     
Sbjct: 197 EAAVVLNDTLNYNQRMVYHFQIEATDG---PHKTQTTFEARVKDVQDKPPVFQ-GSLSTV 252

Query: 375 LAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432
           + ED P  T V+T+ A D D  E  ++ Y++   N    F + +Q G   +  A+PLD +
Sbjct: 253 IDEDSPINTLVLTVHARDGDTGEPRKIVYDLR-TNPNDYFLLDAQTGE--LRTAKPLDRE 309

Query: 433 Q------------ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
                          R ++    +D    S TA   + I D N+  PVF +  Y+ S+ E
Sbjct: 310 ALEDSTGIISLVIRARELVNGVPSDDPLTSATAKATVTIRDVNDSPPVFNHKEYSVSLLE 369

Query: 481 DAPIGTTV-LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN-PQTGAITTNKL 538
           +   GT + L +S +D+DVGIN++    L  ++S   V   + + V    Q      N  
Sbjct: 370 NTLPGTPLALDMSVSDADVGINSKFALRL-DDVS--GVFDVEPKLVTGYSQVNIRVANGT 426

Query: 539 LDRE--TMSGYLLTVTARDGGV-PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
           LD E      +++ V A +    P LS T  + +SV+D NDN+PVF+Q+ Y+A++ E AL
Sbjct: 427 LDYENPNQRKFIVLVVAEETDTNPRLSSTATITVSVLDANDNKPVFEQESYSASVSEAAL 486

Query: 596 VGTSVSQVGATDADVGLNG--RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653
            G  ++ + A D D G  G   I Y L     E   F ++  +GVI      D       
Sbjct: 487 PGQYIATITARDVDSGSYGDSGIRYSLSGTGAE--LFHVNEQTGVISLANCHDNGESNRR 544

Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713
           + + +  D            H++ +D      +   +  T  I     +  T   +    
Sbjct: 545 ERRDLNED-----------EHVEEDDGEGHLEMLSMEAATREIGTEPTVQYT---LITQA 590

Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP 773
           P+E  ++V   +       +     T    DKA       LDYES    Y L  +A    
Sbjct: 591 PEEQASSVPLPAPVPHAAPSGVPAAT-ANDDKA---PQTCLDYES-ETTYFLSYKATDDN 645

Query: 774 LWNDVRV---EILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQ 828
                 V    I VTD ND+ PV +   ++   +     F   P   V A DAD   ++ 
Sbjct: 646 GRGSASVVSLRISVTDANDSPPVCESPLYRASVDEGAVVFD-SPL-IVKARDADTMSRIS 703

Query: 829 YRILSGNNANLIL-LNETTGSMTLSPQLNTNVPKLAT----MEVSVTDGVNEIKAMMQLS 883
           YRI        I  ++  TG + + P    +V  L +      V   DG+      + ++
Sbjct: 704 YRIRGSEQVESIFDIDRETGQIIIRPNATLDVTNLNSDQLIFAVEANDGLFTAHCGVNIT 763

Query: 884 VR 885
           VR
Sbjct: 764 VR 765



 Score =  130 bits (313), Expect = 7e-28
 Identities = 136/483 (28%), Positives = 210/483 (43%), Gaps = 54/483 (11%)

Query: 88  DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTAT---IHVNIIDDN 144
           D F +D  SG +     LDRE+      LV   D+  P  +          I   I+D N
Sbjct: 67  DHFSVDPVSGNITLIKPLDREEKDTLKFLVSIRDRVDPEGESERDNVVEVPITFIILDLN 126

Query: 145 DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQ---MQFS 201
           DN P+F    Y   V+ED +V    +  KI   D D+   S     +    +     +F 
Sbjct: 127 DNPPEFQNTPYEADVNEDAAV-GTTIFDKITVKDRDIVGESLDLKCLPQQQSPEACRKFR 185

Query: 202 IDSLSGDVSLVK-------TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNA 254
           +  +  D ++++       TL+Y Q   Y   I A DG  P ++ TT     ++DV D  
Sbjct: 186 LHIIKRDATILEAAVVLNDTLNYNQRMVYHFQIEATDG--PHKTQTT-FEARVKDVQDKP 242

Query: 255 PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR 314
           P F  SL    + E+ PI   ++ V A D D G   ++ Y     D   N +    +D +
Sbjct: 243 PVFQGSL-STVIDEDSPINTLVLTVHARDGDTGEPRKIVY-----DLRTNPNDYFLLDAQ 296

Query: 315 SGWVYTSGQLDRET----------QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
           +G + T+  LDRE             + + LV      DP  SATA              
Sbjct: 297 TGELRTAKPLDREALEDSTGIISLVIRARELVNGVPSDDPLTSATAKATVTIRDVNDSPP 356

Query: 365 XFMPGQYEVELAEDEPPGTPV-VTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL- 422
            F   +Y V L E+  PGTP+ + ++ +DAD      + +   +  G F +  +   G  
Sbjct: 357 VFNHKEYSVSLLENTLPGTPLALDMSVSDADVGINSKFALRLDDVSGVFDVEPKLVTGYS 416

Query: 423 ---ITVAQ-PLDFK--QERRYVLTVSA--TDSGGR-SDTAMVQINITDANNYAPVFENAP 473
              I VA   LD++   +R++++ V A  TD+  R S TA + +++ DAN+  PVFE   
Sbjct: 417 QVNIRVANGTLDYENPNQRKFIVLVVAEETDTNPRLSSTATITVSVLDANDNKPVFEQES 476

Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGI--NAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
           Y+ASV E A  G  +  ++A D D G   ++ I YSLS   +        + F +N QTG
Sbjct: 477 YSASVSEAALPGQYIATITARDVDSGSYGDSGIRYSLSGTGA--------ELFHVNEQTG 528

Query: 532 AIT 534
            I+
Sbjct: 529 VIS 531



 Score = 91.1 bits (216), Expect = 4e-16
 Identities = 109/422 (25%), Positives = 184/422 (43%), Gaps = 58/422 (13%)

Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523
           N  PVF        ++E+  +GT V  + A D +    + +TY           A H   
Sbjct: 22  NLPPVFTQTLNNIILYENVTVGTVVFRLEAYDPE---GSPVTYGAIG-------ADH--- 68

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD--VEIS----VVDVNDN 577
           F ++P +G IT  K LDRE        V+ RD   P      D  VE+     ++D+NDN
Sbjct: 69  FSVDPVSGNITLIKPLDREEKDTLKFLVSIRDRVDPEGESERDNVVEVPITFIILDLNDN 128

Query: 578 EPVFKQQLYTANIMEDALVGTSV-SQVGATDADV---GLNGR-IHYELDPKD-REEGSFV 631
            P F+   Y A++ EDA VGT++  ++   D D+    L+ + +  +  P+  R+    +
Sbjct: 129 PPEFQNTPYEADVNEDAAVGTTIFDKITVKDRDIVGESLDLKCLPQQQSPEACRKFRLHI 188

Query: 632 IDPASGVIRT----NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687
           I   + ++      N  L+      +  +  A DG   P  +      +++D+ D PPVF
Sbjct: 189 IKRDATILEAAVVLNDTLNYNQRMVYHFQIEATDG---PHKTQTTFEARVKDVQDKPPVF 245

Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747
           +   L+  I E+SPI T +  + A D D G    + Y ++  + ++ F L+ + G    E
Sbjct: 246 QGS-LSTVIDEDSPINTLVLTVHARDGDTGEPRKIVYDLR-TNPNDYFLLDAQTG----E 299

Query: 748 LVTMVDLDYESPRKK---YELVIRA--------ASPPLWN-DVRVEILVTDVNDNAPVMK 795
           L T   LD E+         LVIRA        +  PL +   +  + + DVND+ PV  
Sbjct: 300 LRTAKPLDREALEDSTGIISLVIRARELVNGVPSDDPLTSATAKATVTIRDVNDSPPVFN 359

Query: 796 DFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQL 855
             +   +  ++  P  P     A D  V+D      +  N+   + L++ +G   + P+L
Sbjct: 360 HKEYSVSLLENTLPGTPL----ALDMSVSD----ADVGINSKFALRLDDVSGVFDVEPKL 411

Query: 856 NT 857
            T
Sbjct: 412 VT 413



 Score = 81.0 bits (191), Expect = 4e-13
 Identities = 60/209 (28%), Positives = 100/209 (47%), Gaps = 20/209 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTV-LTLKATDQDIGKNAEVEYTIELVTADT 69
           + + D ND  PVF  ++Y  S+ E    GT + L +  +D D+G N++            
Sbjct: 346 VTIRDVNDSPPVFNHKEYSVSLLENTLPGTPLALDMSVSDADVGINSKF----------A 395

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
           L  +D           V    +++ R    +   +LD E   +   +V    + +  + R
Sbjct: 396 LRLDDVSGVFDVEPKLVTGYSQVNIR----VANGTLDYENPNQRKFIVLVVAEETDTNPR 451

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA--NSAI 187
           LSSTATI V+++D NDN P F +++Y+ SV E  +      IA I A D D G+  +S I
Sbjct: 452 LSSTATITVSVLDANDNKPVFEQESYSASVSE--AALPGQYIATITARDVDSGSYGDSGI 509

Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLD 216
           RY++ G   ++ F ++  +G +SL    D
Sbjct: 510 RYSLSGTGAEL-FHVNEQTGVISLANCHD 537



 Score = 38.3 bits (85), Expect = 3.0
 Identities = 53/228 (23%), Positives = 97/228 (42%), Gaps = 31/228 (13%)

Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
           PPVF        + EN  +GT +  + A+DP+  P   V Y   G D    FS++   G+
Sbjct: 24  PPVFTQTLNNIILYENVTVGTVVFRLEAYDPEGSP---VTYGAIGAD---HFSVDPVSGN 77

Query: 744 DKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR---VEILVT----DVNDNAPVMKD 796
               L+  +D + E    K+ + IR    P     R   VE+ +T    D+NDN P  ++
Sbjct: 78  --ITLIKPLDRE-EKDTLKFLVSIRDRVDPEGESERDNVVEVPITFIILDLNDNPPEFQN 134

Query: 797 FQIIFNNYKDCFPVGP--FGRVPAYDADVT-DKLQYRILSGNNA---------NLILLNE 844
                +  +D   VG   F ++   D D+  + L  + L    +         ++I  + 
Sbjct: 135 TPYEADVNEDA-AVGTTIFDKITVKDRDIVGESLDLKCLPQQQSPEACRKFRLHIIKRDA 193

Query: 845 T--TGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEE 890
           T    ++ L+  LN N   +   ++  TDG ++ +   +  V+ + ++
Sbjct: 194 TILEAAVVLNDTLNYNQRMVYHFQIEATDGPHKTQTTFEARVKDVQDK 241


>UniRef50_Q9Y5F6 Cluster: Protocadherin gamma C5 precursor; n=49;
           Tetrapoda|Rep: Protocadherin gamma C5 precursor - Homo
           sapiens (Human)
          Length = 944

 Score =  252 bits (618), Expect = 8e-65
 Identities = 178/617 (28%), Positives = 277/617 (44%), Gaps = 24/617 (3%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F +   SGAL     +DRE +   +       Q   V++       + V I+D NDN P 
Sbjct: 75  FSLSLMSGALAVNQKIDRESLCGASTSCLLPVQV--VTEHPLELIRVEVEILDLNDNSPS 132

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG-- 207
           F+     + + E  S           A D DVG N+   Y +   N+    ++ +L    
Sbjct: 133 FATPEREMRISE--SAASGARFPLDSAQDPDVGTNTVSFYTL-SPNSHFSLNVKTLKDGK 189

Query: 208 ---DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
              ++ L + LD E    ++LV+ A DGG+P+RS TT + + + D+NDNAP F +S+ + 
Sbjct: 190 PFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRV 249

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
            + EN PIG  ++R+ A D DEG N +L Y+  D       +L   +DP SG ++  G +
Sbjct: 250 GIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNL-FGLDPSSGAIHVLGPI 308

Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
           D E    Y++   A D G P                      +       + E  P GT 
Sbjct: 309 DFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTV 368

Query: 385 VVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444
           V      D D        +            S+N   L+T +QPLD +    Y++ + A+
Sbjct: 369 VGLFNVRDRDSGRNGEVSLDISPDLPFQIKPSENHYSLLT-SQPLDREATSHYIIELLAS 427

Query: 445 DSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502
           D+G  S      +++NI+D N+ AP F    YTA + E+ P G+ +  V+A+D D G NA
Sbjct: 428 DAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNA 487

Query: 503 QITYSLSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL 561
           ++TYS+   + N+        FV +NP+ G I   +  D E +    + V  RD G P L
Sbjct: 488 RLTYSI---VGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPL 544

Query: 562 SDTTDVEISVVDVNDNEPVFK------QQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615
              T + + V+D NDN P         +      +   A  G+ V++V A DAD G N  
Sbjct: 545 HANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAW 604

Query: 616 IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675
           + Y L P+    G F++   +G +RT +AL  +   T  +  +  D G P  SST  V +
Sbjct: 605 LSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLL 664

Query: 676 KIEDINDSPPVFESDCL 692
            +ED +       SD L
Sbjct: 665 VLEDEDPEEMPKSSDFL 681



 Score =  214 bits (523), Expect = 3e-53
 Identities = 166/578 (28%), Positives = 260/578 (44%), Gaps = 39/578 (6%)

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT-DKDYTG 303
           + I D+NDN+P F T   +  +SE+   G       A D D G N    YT++ +  ++ 
Sbjct: 121 VEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSL 180

Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
           NV       P    V    QLDRE QA++QL++TA DGG P RS T              
Sbjct: 181 NVKTLKDGKPFPELVLEQ-QLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNA 239

Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI---TGGNTRGRFSITSQN 418
             F      V + E+ P GT ++ L ATD DE  + +L Y     T    R  F +   +
Sbjct: 240 PTFQSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSS 299

Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTA 476
           G   I V  P+DF++ R Y +   A D G        ++Q+++ D N+ AP    A    
Sbjct: 300 GA--IHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLAN 357

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG--AIT 534
            V E  P+GT V + +  D D G N +++  +S ++           F I P     ++ 
Sbjct: 358 PVLESTPVGTVVGLFNVRDRDSGRNGEVSLDISPDLP----------FQIKPSENHYSLL 407

Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
           T++ LDRE  S Y++ + A D G PSL     + +++ DVNDN P F QQLYTA I+E+ 
Sbjct: 408 TSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENR 467

Query: 595 LVGTSVSQVGATDADVGLNGRIHYEL---DPKDREEGSFV-IDPASGVIRTNKALDRESV 650
             G+ +  V A+D D G N R+ Y +     +     SFV ++P  G I   +  D E +
Sbjct: 468 PPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELL 527

Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE------SDCLTFYISENSPIGT 704
               +     D G+PP  +   +H+ + D ND+ P                +  ++P G+
Sbjct: 528 QMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGS 587

Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDS-NSFSLETRQGSDKAELVTMVDLDYESPRKKY 763
            + ++ A D D G NA + YS+     +   F + T  G  +     + D   +S  ++ 
Sbjct: 588 LVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLED---DSDTQQV 644

Query: 764 ELVIRAASPPLWNDVRVEILVTDVND--NAPVMKDFQI 799
            +++R    P  +     +LV +  D    P   DF I
Sbjct: 645 VVLVRDNGDPSLSSTATVLLVLEDEDPEEMPKSSDFLI 682



 Score =  198 bits (483), Expect = 2e-48
 Identities = 167/593 (28%), Positives = 266/593 (44%), Gaps = 57/593 (9%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           I  ++ +LD ND+SP F   + E  + E A+SG       A D D+G N    YT+   +
Sbjct: 117 IRVEVEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNS 176

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRS-GALLTRASLDREKVARYTVLVKATDQASP 125
             +LN +                   DG+    L+    LDRE  AR+ +++ A D  +P
Sbjct: 177 HFSLNVKTLK----------------DGKPFPELVLEQQLDREAQARHQLVLTAVDGGTP 220

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
                S T  I V ++D NDN P F      V + E+  +    ++ ++ ATD D G N 
Sbjct: 221 AR---SGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPI--GTLLLRLNATDPDEGTNG 275

Query: 186 AIRYAIIGGNT----QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
            + Y+  G +T    +  F +D  SG + ++  +D+E+ R Y +  RA+D G P+     
Sbjct: 276 QLDYS-FGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARDQGQPAMEGHC 334

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
            + +++ DVNDNAP    +     V E+ P+G  +      D D G N E++  ++    
Sbjct: 335 VIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGEVSLDISP--- 391

Query: 302 TGNVDLPITIDPRSGW--VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
               DLP  I P      + TS  LDRE  + Y + + A+D G P      T        
Sbjct: 392 ----DLPFQIKPSENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNISDV 447

Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRG--RFSIT 415
                 F    Y   + E+ PPG+ + T+ A+D D  DN RL Y I G   +G    S  
Sbjct: 448 NDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASSFV 507

Query: 416 SQNGR-GLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAP-VFE 470
             N   G I   +  D++  +   + V   DSG     ++T++  + + D N+ AP V  
Sbjct: 508 YVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSL-HVFVLDENDNAPAVLH 566

Query: 471 NAP---YTA--SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525
             P   ++A   +   AP G+ V  V+A D+D G NA ++YSL  + +   +      F+
Sbjct: 567 PRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGL------FL 620

Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578
           ++  TG + T + L  +      + V  RD G PSLS T  V + + D +  E
Sbjct: 621 VSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPEE 673



 Score =  132 bits (318), Expect = 2e-28
 Identities = 103/329 (31%), Positives = 156/329 (47%), Gaps = 27/329 (8%)

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
           SV E++  GT V  V+    D+G+      S   ++ +E    + + F ++  +GA+  N
Sbjct: 34  SVVEESEPGTLVGNVA---QDLGLKMTDLLSRRLQLGSE---ENGRYFSLSLMSGALAVN 87

Query: 537 KLLDRETMSGYLLTVTARDGGVPSLS-DTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
           + +DRE++ G   +       V     +   VE+ ++D+NDN P F        I E A 
Sbjct: 88  QKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISESAA 147

Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI----DPASGVIRTNKALDRESVA 651
            G       A D DVG N    Y L P      +        P   ++   + LDRE+ A
Sbjct: 148 SGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELV-LEQQLDREAQA 206

Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711
            H L   A+DGGTP +S T ++ + + DIND+ P F+S  L   I EN+PIGT +  + A
Sbjct: 207 RHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRLNA 266

Query: 712 HDPDEGPNAVVHYSIKGGDDS-----NSFSLETRQGSDKAELVTMVDLDYESPRKKYELV 766
            DPDEG N  + YS   GD +     N F L+   G+    +  +  +D+E  R  YE+ 
Sbjct: 267 TDPDEGTNGQLDYSF--GDHTSEAVRNLFGLDPSSGA----IHVLGPIDFEESR-FYEIH 319

Query: 767 IRA---ASPPLWNDVRVEILVTDVNDNAP 792
            RA     P +     +++ V DVNDNAP
Sbjct: 320 ARARDQGQPAMEGHCVIQVDVGDVNDNAP 348


>UniRef50_Q5ICW6 Cluster: Protocadherin 15a; n=8; Clupeocephala|Rep:
            Protocadherin 15a - Danio rerio (Zebrafish) (Brachydanio
            rerio)
          Length = 1796

 Score =  248 bits (608), Expect = 1e-63
 Identities = 238/832 (28%), Positives = 386/832 (46%), Gaps = 59/832 (7%)

Query: 88   DVFRIDGRSGALLTRASLDREKVARYTVLVKAT-DQASPVSDRLSSTATIHVNIIDDNDN 146
            + F ++  +  L    S+DRE   R+++++KA  D   P    L + + + + I+D+N+ 
Sbjct: 341  EFFTLNRSTAELRLLKSVDRELYQRFSLVIKAEQDNGHP----LPAYSKLEIEILDENNQ 396

Query: 147  YPQFSEKTYTVSVDEDISV-TDNPVIAKIKAT------DADVGANSAIRYAIIGGNTQMQ 199
             P F + +Y   V E  SV T     A + A       D D+      +  I        
Sbjct: 397  APYFQQSSYRGFVSESSSVGTTISASANLTAPLAIIALDNDIEETKDPQLKITLNEYTSI 456

Query: 200  FSIDS--LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF 257
            F+I +  ++  ++L+K +D E   +Y L + A DG   SR  T  +L+   D NDN P F
Sbjct: 457  FTITTSGITRFLTLLKPVDREIQTNYTLTLVATDGVQQSRPVTVDILVI--DANDNTPTF 514

Query: 258  YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317
                +   +  N+  G +++++ A DAD G+N  +TY +   D+   +     I+ R+G 
Sbjct: 515  AQVSYSVEIFTNMLPGETVLQLMAQDADAGLNGLITYAILAGDHGDFI-----INNRTGR 569

Query: 318  VYTSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXXXXFMPGQ-YEVE 374
            +  +  +       Y L V A D       RS+  T                P Q Y +E
Sbjct: 570  ITLAPGVMLTVGRSYALTVRAADNAPDTERRSSITTVYIEVLPPNNQSPPRFPLQTYNLE 629

Query: 375  LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434
            ++E    G  ++ L ATD + D  + Y I  G+ +  F+++   G  L+ +A+PLD +  
Sbjct: 630  ISEAMRIGAILLNLQATDRELDP-ITYRIETGDPQEVFNLSRTIG--LLLLAKPLDRETI 686

Query: 435  RRYVLTVSATDSG-GRSDTAMVQINITDANNYAPVFE-NAPYTASVFEDAPIGTTVLVVS 492
             +Y L V+A+D   G   TA V I ITD N+  P F+   P   +V E+      V  V 
Sbjct: 687  DQYRLIVTASDGHPGGISTATVSIVITDVNDNDPTFDLTLPRNLTVREEEA-NVFVGQVR 745

Query: 493  ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552
            ATD D G+N Q+ Y L S  S          F IN  TG+I T   LDRET S Y L V 
Sbjct: 746  ATDPDGGLNGQVRYRLLSFAS---------LFSIN-STGSIFTAVPLDRETRSRYDLIVE 795

Query: 553  ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612
            A DG V     T  + + V+D+NDN PVF Q +YT N+ E+   G+ + ++ A DAD+  
Sbjct: 796  ASDGAVDPRRTTITLLVEVLDINDNSPVFSQPVYTVNVPENTPAGSIILRLTAVDADLVS 855

Query: 613  NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA----THDLKAVAIDGGTPPQS 668
            N  + Y +  +   +  F ++  +GVI   +ALD ES+A    T+  +  A+D G     
Sbjct: 856  N--VTYRIKTEAALQ-LFAVNRLTGVISVLQALDFESLAAGNSTYTFEVEALDHGGVLPP 912

Query: 669  STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA--HDPDEGPNAVVHYSI 726
             T  V ++I D+ND  PVF        ++ N+  GT I  + A   DP   P + V Y +
Sbjct: 913  GTATVSVRITDMNDFSPVFRQALYKGLVAPNAEKGTVITTVLAEDQDPPGTPASKVRYRV 972

Query: 727  KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEIL 783
                   S S+   + +D   ++T V+L+ E P   ++LV+ A     P   N   VEI 
Sbjct: 973  DQELSPYSGSIFDVE-TDTGLVITKVNLN-EQPTTVFKLVVMAYDDGEPVKTNRTTVEIT 1030

Query: 784  VTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLILL 842
            V   +   P+  + +  F+   +  P+G P G + A   + T  + Y I+SGN   +  +
Sbjct: 1031 VLQPS-RIPIFTEEEYRFSPVSENAPIGTPVGLILAAATNTT--VVYSIVSGNEGGVFTV 1087

Query: 843  NETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLN 894
            N++TG +  +  L+        + V   D +  I A ++   +  T ++ +N
Sbjct: 1088 NKSTGIIYTNKSLDYENVTSYVLRVQ-ADSLTVILANLRAPSKTNTAKVFIN 1138



 Score =  248 bits (606), Expect = 2e-63
 Identities = 257/848 (30%), Positives = 378/848 (44%), Gaps = 109/848 (12%)

Query: 7   IHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-----LKATDQDIGKNAEVEY 60
           +H+ +I V D ND++P F+  +Y  SV E    GTT+ T       ATD D G N ++EY
Sbjct: 135 LHEVRIVVRDRNDNTPRFQQPRYYVSVNELTPVGTTIFTGFSGNNGATDIDDGPNGQIEY 194

Query: 61  TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGR-SGALLTRASLDREKVARYTVLVKA 119
            I+       NP D                RI G  SG ++    L+ E+  RY ++V+A
Sbjct: 195 AIQY------NPNDPMSNRTV---------RIAGTLSGNIVLAERLNYEERTRYLIIVQA 239

Query: 120 TDQASPVSDRLSSTATIHVNIIDDNDNYPQF------------SEKTYTVSVDEDISVTD 167
            D+A     R ++T T+ ++++D +D  P F            +  TY V++ E      
Sbjct: 240 NDRAPYPGTRRTATTTLTLDVLDGDDLGPMFLPCVLVNNTQDCNPVTYRVAIPELTDPNK 299

Query: 168 -NP--VIAKIKATDAD-----VGANSAIRYAIIGGNTQMQ---FSIDSLSGDVSLVKTLD 216
            NP  V   I+A D D           I Y I+ G        F+++  + ++ L+K++D
Sbjct: 300 LNPLNVTPPIRAIDQDRNIQPPSDRPGILYFILVGTPSTYPEFFTLNRSTAELRLLKSVD 359

Query: 217 YEQVRSYRLVIRA-QDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275
            E  + + LVI+A QD G P  +  ++L I I D N+ AP F  S ++  VSE+  +G +
Sbjct: 360 RELYQRFSLVIKAEQDNGHPLPA-YSKLEIEILDENNQAPYFQQSSYRGFVSESSSVGTT 418

Query: 276 IVRVQAYDADEGVNAELTYTMTDKDY--TGNVDLPITIDPRSG--WVYTSG--------- 322
           I       A   + A L     D D   T +  L IT++  +    + TSG         
Sbjct: 419 I------SASANLTAPLAIIALDNDIEETKDPQLKITLNEYTSIFTITTSGITRFLTLLK 472

Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382
            +DRE Q  Y L + ATDG    +S   T              F    Y VE+  +  PG
Sbjct: 473 PVDREIQTNYTLTLVATDG--VQQSRPVTVDILVIDANDNTPTFAQVSYSVEIFTNMLPG 530

Query: 383 TPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440
             V+ L A DAD   +  + Y I  G+  G F I ++ GR  IT+A  +     R Y LT
Sbjct: 531 ETVLQLMAQDADAGLNGLITYAILAGD-HGDFIINNRTGR--ITLAPGVMLTVGRSYALT 587

Query: 441 VSATDSG----GRSDTAMVQINITDANNYAPV-FENAPYTASVFEDAPIGTTVLVVSATD 495
           V A D+      RS    V I +   NN +P  F    Y   + E   IG  +L + ATD
Sbjct: 588 VRAADNAPDTERRSSITTVYIEVLPPNNQSPPRFPLQTYNLEISEAMRIGAILLNLQATD 647

Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555
            ++     ITY + +    E        F ++   G +   K LDRET+  Y L VTA D
Sbjct: 648 RELD---PITYRIETGDPQEV-------FNLSRTIGLLLLAKPLDRETIDQYRLIVTASD 697

Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615
           G    +S T  V I + DVNDN+P F   L     + +      V QV ATD D GLNG+
Sbjct: 698 GHPGGIS-TATVSIVITDVNDNDPTFDLTLPRNLTVREEEANVFVGQVRATDPDGGLNGQ 756

Query: 616 IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675
           + Y L        S     ++G I T   LDRE+ + +DL   A DG   P+ +T+ + +
Sbjct: 757 VRYRL----LSFASLFSINSTGSIFTAVPLDRETRSRYDLIVEASDGAVDPRRTTITLLV 812

Query: 676 KIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735
           ++ DIND+ PVF     T  + EN+P G+ I  + A D D   N  V Y IK       F
Sbjct: 813 EVLDINDNSPVFSQPVYTVNVPENTPAGSIILRLTAVDADLVSN--VTYRIKTEAALQLF 870

Query: 736 SLETRQGSDKAELVTMVDLDYES---PRKKYELVIRAAS-----PPLWNDVRVEILVTDV 787
           ++    G     +  +  LD+ES       Y   + A       PP      V + +TD+
Sbjct: 871 AVNRLTG----VISVLQALDFESLAAGNSTYTFEVEALDHGGVLPP--GTATVSVRITDM 924

Query: 788 NDNAPVMK 795
           ND +PV +
Sbjct: 925 NDFSPVFR 932



 Score =  246 bits (602), Expect = 7e-63
 Identities = 240/852 (28%), Positives = 378/852 (44%), Gaps = 78/852 (9%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I +LD N+ +P F+   Y   V E +S GTT          I  +A +   + ++  D 
Sbjct: 387  EIEILDENNQAPYFQQSSYRGFVSESSSVGTT----------ISASANLTAPLAIIALDN 436

Query: 70   LNPEDAXXXXXXXXXXVQDVFRI--DGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
               E               +F I   G +  L     +DRE    YT+ + ATD      
Sbjct: 437  DIEETKDPQLKITLNEYTSIFTITTSGITRFLTLLKPVDREIQTNYTLTLVATDGVQQ-- 494

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
               S   T+ + +ID NDN P F++ +Y+V +  ++       + ++ A DAD G N  I
Sbjct: 495  ---SRPVTVDILVIDANDNTPTFAQVSYSVEIFTNM--LPGETVLQLMAQDADAGLNGLI 549

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS--RSNTTQLLI 245
             YAI+ G+    F I++ +G ++L   +     RSY L +RA D    +  RS+ T + I
Sbjct: 550  TYAILAGD-HGDFIINNRTGRITLAPGVMLTVGRSYALTVRAADNAPDTERRSSITTVYI 608

Query: 246  NIRDVNDNAP-RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
             +   N+ +P RF    +   +SE + IG  ++ +QA D +      +TY +   D    
Sbjct: 609  EVLPPNNQSPPRFPLQTYNLEISEAMRIGAILLNLQATDRELD---PITYRIETGDPQEV 665

Query: 305  VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
             +L  TI    G +  +  LDRET  +Y+L+VTA+DG  P   +TAT             
Sbjct: 666  FNLSRTI----GLLLLAKPLDRETIDQYRLIVTASDG-HPGGISTATVSIVITDVNDNDP 720

Query: 365  XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGL 422
             F           +E     V  + ATD D   + ++ Y +   +    FSI   N  G 
Sbjct: 721  TFDLTLPRNLTVREEEANVFVGQVRATDPDGGLNGQVRYRLL--SFASLFSI---NSTGS 775

Query: 423  ITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
            I  A PLD +   RY L V A+D     R  T  + + + D N+ +PVF    YT +V E
Sbjct: 776  IFTAVPLDRETRSRYDLIVEASDGAVDPRRTTITLLVEVLDINDNSPVFSQPVYTVNVPE 835

Query: 481  DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
            + P G+ +L ++A D+D+  N  +TY + +E +        Q F +N  TG I+  + LD
Sbjct: 836  NTPAGSIILRLTAVDADLVSN--VTYRIKTEAAL-------QLFAVNRLTGVISVLQALD 886

Query: 541  RETM----SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
             E++    S Y   V A D G      T  V + + D+ND  PVF+Q LY   +  +A  
Sbjct: 887  FESLAAGNSTYTFEVEALDHGGVLPPGTATVSVRITDMNDFSPVFRQALYKGLVAPNAEK 946

Query: 597  GTSVSQVGATDADVGLN--GRIHYELDPK-DREEGS-FVIDPASGVIRTNKALDRESVAT 652
            GT ++ V A D D       ++ Y +D +     GS F ++  +G++ T   L+ +    
Sbjct: 947  GTVITTVLAEDQDPPGTPASKVRYRVDQELSPYSGSIFDVETDTGLVITKVNLNEQPTTV 1006

Query: 653  HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
              L  +A D G P +++   V I +   +  P   E +     +SEN+PIGT +G I A 
Sbjct: 1007 FKLVVMAYDDGEPVKTNRTTVEITVLQPSRIPIFTEEEYRFSPVSENAPIGTPVGLILA- 1065

Query: 713  DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS- 771
                  N  V YSI  G++   F++    G     + T   LDYE+    Y L ++A S 
Sbjct: 1066 ---AATNTTVVYSIVSGNEGGVFTVNKSTGI----IYTNKSLDYENVTS-YVLRVQADSL 1117

Query: 772  ---------PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD 822
                     P   N  +V I V D ND+ PV      I    +D        ++ A D D
Sbjct: 1118 TVILANLRAPSKTNTAKVFINVQDENDHPPVFSRQVYIGGVTEDTKTFTTVLKIVATDVD 1177

Query: 823  VTD--KLQYRIL 832
              +  K+ YR++
Sbjct: 1178 TGNYSKMAYRLI 1189



 Score =  217 bits (530), Expect = 4e-54
 Identities = 220/758 (29%), Positives = 335/758 (44%), Gaps = 77/758 (10%)

Query: 11   INVLDCNDHSPV-FEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            I VL  N+ SP  F +Q Y   + E    G  +L L+ATD+++     + Y IE  T D 
Sbjct: 608  IEVLPPNNQSPPRFPLQTYNLEISEAMRIGAILLNLQATDRELDP---ITYRIE--TGDP 662

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                             Q+VF +    G LL    LDRE + +Y ++V A+D   P    
Sbjct: 663  -----------------QEVFNLSRTIGLLLLAKPLDRETIDQYRLIVTASD-GHPGG-- 702

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTD---NPVIAKIKATDADVGANSA 186
              STAT+ + I D NDN P     T+ +++  +++V +   N  + +++ATD D G N  
Sbjct: 703  -ISTATVSIVITDVNDNDP-----TFDLTLPRNLTVREEEANVFVGQVRATDPDGGLNGQ 756

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            +RY ++  +    FSI+S +G +     LD E    Y L++ A DG    R  T  LL+ 
Sbjct: 757  VRYRLL--SFASLFSINS-TGSIFTAVPLDRETRSRYDLIVEASDGAVDPRRTTITLLVE 813

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            + D+NDN+P F   ++  +V EN P G  I+R+ A DAD  + + +TY +  +     + 
Sbjct: 814  VLDINDNSPVFSQPVYTVNVPENTPAGSIILRLTAVDAD--LVSNVTYRIKTE---AALQ 868

Query: 307  LPITIDPRSGWVYTSGQLDRETQAK----YQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
            L   ++  +G +     LD E+ A     Y   V A D G      TAT           
Sbjct: 869  L-FAVNRLTGVISVLQALDFESLAAGNSTYTFEVEALDHGGVLPPGTATVSVRITDMNDF 927

Query: 363  XXXFMPGQYEVELAEDEPPGTPVVTLTATDADED----NRLHYEITGGNTRGRFSITS-Q 417
               F    Y+  +A +   GT + T+ A D D      +++ Y +    +    SI   +
Sbjct: 928  SPVFRQALYKGLVAPNAEKGTVITTVLAEDQDPPGTPASKVRYRVDQELSPYSGSIFDVE 987

Query: 418  NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDAN-NYAPVFENAPYTA 476
               GL+     L+ +    + L V A D G    T    + IT    +  P+F    Y  
Sbjct: 988  TDTGLVITKVNLNEQPTTVFKLVVMAYDDGEPVKTNRTTVEITVLQPSRIPIFTEEEYRF 1047

Query: 477  S-VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
            S V E+APIGT V ++ A  +    N  + YS+ S   NE        F +N  TG I T
Sbjct: 1048 SPVSENAPIGTPVGLILAAAT----NTTVVYSIVS--GNEGGV-----FTVNKSTGIIYT 1096

Query: 536  NKLLDRETMSGYLLTVTARDGGV-------PSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588
            NK LD E ++ Y+L V A    V       PS ++T  V I+V D ND+ PVF +Q+Y  
Sbjct: 1097 NKSLDYENVTSYVLRVQADSLTVILANLRAPSKTNTAKVFINVQDENDHPPVFSRQVYIG 1156

Query: 589  NIMEDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALD 646
             + ED    T+V ++ ATD D G   ++ Y L   P    + SFVI+P +GVI++     
Sbjct: 1157 GVTEDTKTFTTVLKIVATDVDTGNYSKMAYRLIIPPTTEGQDSFVIEPYTGVIKSAIMFR 1216

Query: 647  RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706
                +    + VA D      +S   V + + +  D   V  S+     + EN     +I
Sbjct: 1217 NMRRSYFKFQVVATDDYGKGLTSKADVVVSVVNALDM-QVVVSNVPPTVVEENKEQLISI 1275

Query: 707  GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD 744
             E    D   G   +V  SI        + LE    SD
Sbjct: 1276 LERYVQDQIPGAKVIVE-SIGPRRHGEGYELEDYSKSD 1312


>UniRef50_Q9VAF5 Cluster: CG31009-PA; n=9; Diptera|Rep: CG31009-PA -
           Drosophila melanogaster (Fruit fly)
          Length = 1706

 Score =  246 bits (601), Expect = 9e-63
 Identities = 252/885 (28%), Positives = 391/885 (44%), Gaps = 81/885 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVL-TLKATDQDIGKNAEVEYTIELVTADT 69
           + V D ND++P F    YE +V E    GTT+   ++A D+D G N  VEY I   + ++
Sbjct: 130 VRVSDINDNAPRFMNTPYEVTVPESTPVGTTIFRNIQALDKDAGVNGLVEYFIAEGSPNS 189

Query: 70  LNPEDAXXXXXXXXXXVQDVFRID-GRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
            N E                F I     G +    +LD EK+  Y + + A+D+A   +D
Sbjct: 190 TNVEKYSADGYGT-------FAISFPHQGQVTVAKTLDFEKIQTYYLTIVASDRARNTAD 242

Query: 129 RLSSTATIHVNIIDDNDNYPQF------SEKTYTVSVDEDISVTDNPVIA-------KIK 175
           RLSST T+ VNI D ND  P F      S     ++ +   SV    ++        +I+
Sbjct: 243 RLSSTTTLTVNIADSNDLDPSFIYSGCVSLDGACINPEYSASVPAGSLLGVLTVLPERIQ 302

Query: 176 ATDADVGANSAIRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD- 231
           A D D   NS IRY+    + GN    F ID  +G +   K +D    + Y ++++A++ 
Sbjct: 303 AVDLDT-INSPIRYSFASGMPGNYADYFQIDESTGVLKQTKAVDTSTAKKYDIIVKAEEV 361

Query: 232 GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNA 290
              P R  T +L I ++ V+ N P   +S  +  V EN PIG  ++            +A
Sbjct: 362 SPGPQRFTTAKLEIFVKPVDANPPVISSSQAEGYVDENSPIGTRVLDAHGNPISFMTTDA 421

Query: 291 ELTYTMTDKDYTGNVDLP-ITIDPRSGWVYTSGQLDRETQA--KYQLLVTATDGGDPPRS 347
           +L+ +    DY   +  P   +      V     LDR+  A  +++  V A +    PR+
Sbjct: 422 DLSDSDPKPDYIYELTTPSFNVTGDGILVVNEENLDRDPPAPGRFKFQVVARE----PRT 477

Query: 348 ATATXXXXXXXXXXXXXXFMPGQYEVE----LAEDEPPGTPVVTLTATDADEDNR--LHY 401
             A+                P    V      A D+     V  +TATD DE     + Y
Sbjct: 478 NAASAPLSLTVHLRDVNDNAPKLAMVAPISITAGDQSESRLVTQVTATDNDEGPNAVVTY 537

Query: 402 EITGGNTRG--RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINI 459
            I   +  G  +F+I +  G  + T  + L  +Q   Y +TV ATD GG S  A+V++++
Sbjct: 538 SIYHVSNNGIQKFTINATTGE-IRTQGRLLAGEQ---YSITVQATDIGGLSSQAIVEVSV 593

Query: 460 TDA-NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518
           T   N   P F+   Y   V E A I +TV VV A D +   N  + YS+ S   N+   
Sbjct: 594 TPGPNTKPPRFQKPIYEVQVSEGAEINSTVTVVHAEDPE---NDAVVYSIIS--GNDL-- 646

Query: 519 HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578
              +QF +  ++G I   + LDRE+++ Y L + A D G   LS +  V I V D+ND  
Sbjct: 647 ---RQFAVGQESGVIIVIRKLDRESLTRYQLILKAEDTG--GLSSSATVNIKVTDINDKN 701

Query: 579 PVFK-QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637
           P F+   L     +E+     SV  V ATDAD G+N  I Y + P D     F I+  SG
Sbjct: 702 PEFEASTLPYVFQVEEGKAQASVGVVHATDADEGINAEITYSI-PTDI---PFTINATSG 757

Query: 638 VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697
            I T K LD E +  +     A DG    +  T  V + + D+ D  P F    +  +I 
Sbjct: 758 EILTAKELDYEQLNEYKFVVTAKDGAPDARLGTASVTVMVLDLPDEVPKFSDARIDVHIP 817

Query: 698 ENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757
           EN      +  ++A DPD  P   + Y ++ G ++  F +  + G    E+ T+  LDYE
Sbjct: 818 ENEE-NFLVATVQAFDPDSMPE--ITYVLRKG-NAELFKVSEKSG----EVRTIKGLDYE 869

Query: 758 SPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN--NYKDCFPVGP-FG 814
           S +K+++L I              +LV DV D   +   F  + +     D   +G    
Sbjct: 870 S-QKQHQLTIGTIENDGNGPGDTILLVVDVEDRNDLPPRFITVPDPVTVNDDQGIGTIIA 928

Query: 815 RVPAYDADVT---DKLQYRILS-GNNANLILLNETTGSMTLSPQL 855
            +PA D D T   + ++Y I+  G       ++  TG++ +  +L
Sbjct: 929 TLPAIDGDGTSPGNVVRYEIVGRGKAPKYFQVDPDTGAVRIRDEL 973



 Score =  224 bits (547), Expect = 3e-56
 Identities = 223/774 (28%), Positives = 342/774 (44%), Gaps = 54/774 (6%)

Query: 11  INVLDCNDHSPVFEMQQYEASVR-EGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +N+ D ND  P F    Y   V  +GA               +G    +   I+ V  DT
Sbjct: 252 VNIADSNDLDPSFI---YSGCVSLDGACINPEYSASVPAGSLLGVLTVLPERIQAVDLDT 308

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
           +N                D F+ID  +G L    ++D     +Y ++VKA ++ SP   R
Sbjct: 309 INSPIRYSFASGMPGNYADYFQIDESTGVLKQTKAVDTSTAKKYDIIVKA-EEVSPGPQR 367

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED-------ISVTDNPVIAKIKATDADVG 182
            + TA + + +   + N P  S       VDE+       +    NP+      TDAD+ 
Sbjct: 368 FT-TAKLEIFVKPVDANPPVISSSQAEGYVDENSPIGTRVLDAHGNPI--SFMTTDADL- 423

Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSLV---KTLDYEQVRS--YRLVIRAQDGGSPSR 237
           ++S  +   I   T   F++   +GD  LV   + LD +      ++  + A++  + + 
Sbjct: 424 SDSDPKPDYIYELTTPSFNV---TGDGILVVNEENLDRDPPAPGRFKFQVVAREPRTNAA 480

Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297
           S    L +++RDVNDNAP+          + +      + +V A D DEG NA +TY++ 
Sbjct: 481 SAPLSLTVHLRDVNDNAPKLAMVAPISITAGDQSESRLVTQVTATDNDEGPNAVVTYSIY 540

Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357
               + N     TI+  +G + T G+L    Q  Y + V ATD G     A         
Sbjct: 541 H--VSNNGIQKFTINATTGEIRTQGRLLAGEQ--YSITVQATDIGGLSSQAIVEVSVTPG 596

Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ 417
                   F    YEV+++E     + V  + A D + D  + Y I  GN   +F++  +
Sbjct: 597 PNTKPPR-FQKPIYEVQVSEGAEINSTVTVVHAEDPEND-AVVYSIISGNDLRQFAVGQE 654

Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENA--PYT 475
           +G  +I V + LD +   RY L + A D+GG S +A V I +TD N+  P FE +  PY 
Sbjct: 655 SG--VIIVIRKLDRESLTRYQLILKAEDTGGLSSSATVNIKVTDINDKNPEFEASTLPYV 712

Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
             V E+     +V VV ATD+D GINA+ITYS+ ++I           F IN  +G I T
Sbjct: 713 FQV-EEGKAQASVGVVHATDADEGINAEITYSIPTDIP----------FTINATSGEILT 761

Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
            K LD E ++ Y   VTA+DG   +   T  V + V+D+ D  P F       +I E+  
Sbjct: 762 AKELDYEQLNEYKFVVTAKDGAPDARLGTASVTVMVLDLPDEVPKFSDARIDVHIPENE- 820

Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655
               V+ V A D D      I Y L   + E   F +   SG +RT K LD ES   H L
Sbjct: 821 ENFLVATVQAFDPD--SMPEITYVLRKGNAE--LFKVSEKSGEVRTIKGLDYESQKQHQL 876

Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
               I+        T+++ + +ED ND PP F +      ++++  IGT I  + A D D
Sbjct: 877 TIGTIENDGNGPGDTILLVVDVEDRNDLPPRFITVPDPVTVNDDQGIGTIIATLPAIDGD 936

Query: 716 -EGPNAVVHYSIKG-GDDSNSFSLETRQGSDKA--ELVTMVDLDYESPRKKYEL 765
              P  VV Y I G G     F ++   G+ +   EL    D +Y+   + Y+L
Sbjct: 937 GTSPGNVVRYEIVGRGKAPKYFQVDPDTGAVRIRDELRKEEDTEYQVDIRAYDL 990



 Score =  218 bits (532), Expect = 2e-54
 Identities = 206/768 (26%), Positives = 343/768 (44%), Gaps = 88/768 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-LKATDQDIGKNAEVEYTIELVTADT 69
            +++ D ND++P   M     S+  G  S + ++T + ATD D G NA V Y+I  V+ + 
Sbjct: 488  VHLRDVNDNAPKLAMVA-PISITAGDQSESRLVTQVTATDNDEGPNAVVTYSIYHVSNNG 546

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            +                   F I+  +G + T+  L   +  +Y++ V+ATD        
Sbjct: 547  IQK-----------------FTINATTGEIRTQGRLLAGE--QYSITVQATDIGG----- 582

Query: 130  LSSTATIHVNIIDD-NDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            LSS A + V++    N   P+F +  Y V V E   +  N  +  + A D +   N A+ 
Sbjct: 583  LSSQAIVEVSVTPGPNTKPPRFQKPIYEVQVSEGAEI--NSTVTVVHAEDPE---NDAVV 637

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            Y+II GN   QF++   SG + +++ LD E +  Y+L+++A+D G  S S T    I + 
Sbjct: 638  YSIISGNDLRQFAVGQESGVIIVIRKLDRESLTRYQLILKAEDTGGLSSSATVN--IKVT 695

Query: 249  DVNDNAPRFYTSLFQESVS-ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            D+ND  P F  S        E      S+  V A DADEG+NAE+TY++         D+
Sbjct: 696  DINDKNPEFEASTLPYVFQVEEGKAQASVGVVHATDADEGINAEITYSIP-------TDI 748

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
            P TI+  SG + T+ +LD E   +Y+ +VTA DG    R  TA+              F 
Sbjct: 749  PFTINATSGEILTAKELDYEQLNEYKFVVTAKDGAPDARLGTASVTVMVLDLPDEVPKFS 808

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
              + +V + E+E     V T+ A D D    + Y +  GN    F ++ ++G   +   +
Sbjct: 809  DARIDVHIPENEE-NFLVATVQAFDPDSMPEITYVLRKGNAE-LFKVSEKSGE--VRTIK 864

Query: 428  PLDFKQERRYVLTVSA--TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
             LD++ ++++ LT+     D  G  DT ++ +++ D N+  P F   P   +V +D  IG
Sbjct: 865  GLDYESQKQHQLTIGTIENDGNGPGDTILLVVDVEDRNDLPPRFITVPDPVTVNDDQGIG 924

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
            T +  + A D D      +   +  EI     A   + F ++P TGA+     L +E  +
Sbjct: 925  TIIATLPAIDGDGTSPGNV---VRYEIVGRGKA--PKYFQVDPDTGAVRIRDELRKEEDT 979

Query: 546  GYLLTVTARDGGVPSLSDTTDVEISV---VDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
             Y + + A D G P LS    + + V   +   +NE     +L +   M    +G + S 
Sbjct: 980  EYQVDIRAYDLGEPQLSSVAPLRVDVHHLLSSGNNEIKLDNKLESGTGMSSESIGLAFSD 1039

Query: 603  VGATDA-----DVGLNGRIHYELDPKDREEG------SFVIDPASGVIRTNKA------- 644
               T +     +     ++   ++ K   +G       FV     G+   + A       
Sbjct: 1040 DSYTTSVPESMEANSTLKLIQIVNSKTSGDGPPAFRCEFVSGNGGGIFNLSSADHGCNLL 1099

Query: 645  ----LDRESVATHDLKAVAIDGG--TPPQSSTVIVHIKIEDINDSPPVFESDCL-----T 693
                LD E+ +++ L+           P   T  V I ++D ND+ P FE + L     T
Sbjct: 1100 LIQPLDFENKSSYSLQLRLTSHRYFVNPLKDTTSVEIIVQDENDNAPEFEFNRLRGQQDT 1159

Query: 694  FY--ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLET 739
            FY  ++E   + TTI ++RA D D G    V Y++   DD N  ++ T
Sbjct: 1160 FYTVVTEEMDVDTTILQVRATDRDSGKFGTVRYTLY-DDDENRVNMPT 1206



 Score =  213 bits (521), Expect = 4e-53
 Identities = 233/816 (28%), Positives = 352/816 (43%), Gaps = 91/816 (11%)

Query: 87  QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146
           Q +F+++G+   LL     D E ++     V  T +    S     T  I V + D NDN
Sbjct: 83  QPIFQLNGKKLQLLQPLDRDEENLSHIVFQVSCTTR----STGKKRTIPIIVRVSDINDN 138

Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQM----QFSI 202
            P+F    Y V+V E   V    +   I+A D D G N  + Y I  G+       ++S 
Sbjct: 139 APRFMNTPYEVTVPESTPV-GTTIFRNIQALDKDAGVNGLVEYFIAEGSPNSTNVEKYSA 197

Query: 203 DSLS---------GDVSLVKTLDYEQVRSYRLVIRAQD---GGSPSRSNTTQLLINIRDV 250
           D            G V++ KTLD+E++++Y L I A D     +   S+TT L +NI D 
Sbjct: 198 DGYGTFAISFPHQGQVTVAKTLDFEKIQTYYLTIVASDRARNTADRLSSTTTLTVNIADS 257

Query: 251 NDNAPRFYTS--------LFQESVSENVPIGYSI-------VRVQAYDADEGVNAELTYT 295
           ND  P F  S              S +VP G  +        R+QA D D  +N+ + Y+
Sbjct: 258 NDLDPSFIYSGCVSLDGACINPEYSASVPAGSLLGVLTVLPERIQAVDLDT-INSPIRYS 316

Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD-GGDPPRSATATXXX 354
                  GN      ID  +G +  +  +D  T  KY ++V A +    P R  TA    
Sbjct: 317 FA-SGMPGNYADYFQIDESTGVLKQTKAVDTSTAKKYDIIVKAEEVSPGPQRFTTAKLEI 375

Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPV-------VTLTATDAD-EDNRLHYEITGG 406
                          Q E  + E+ P GT V       ++   TDAD  D+    +    
Sbjct: 376 FVKPVDANPPVISSSQAEGYVDENSPIGTRVLDAHGNPISFMTTDADLSDSDPKPDYIYE 435

Query: 407 NTRGRFSITSQNGRGLITVAQ---PLDFKQERRYVLTVSATD--SGGRSDTAMVQINITD 461
            T   F++T   G G++ V +     D     R+   V A +  +   S    + +++ D
Sbjct: 436 LTTPSFNVT---GDGILVVNEENLDRDPPAPGRFKFQVVAREPRTNAASAPLSLTVHLRD 492

Query: 462 ANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521
            N+ AP        +    D      V  V+ATD+D G NA +TYS+   +SN  +    
Sbjct: 493 VNDNAPKLAMVAPISITAGDQSESRLVTQVTATDNDEGPNAVVTYSI-YHVSNNGI---- 547

Query: 522 QQFVINPQTGAI-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV-DVNDNEP 579
           Q+F IN  TG I T  +LL  E    Y +TV A D G   LS    VE+SV    N   P
Sbjct: 548 QKFTINATTGEIRTQGRLLAGEQ---YSITVQATDIG--GLSSQAIVEVSVTPGPNTKPP 602

Query: 580 VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639
            F++ +Y   + E A + ++V+ V A D +   N  + Y +     +   F +   SGVI
Sbjct: 603 RFQKPIYEVQVSEGAEINSTVTVVHAEDPE---NDAVVYSI-ISGNDLRQFAVGQESGVI 658

Query: 640 RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS-E 698
              + LDRES+  + L   A D G    SS+  V+IK+ DIND  P FE+  L +    E
Sbjct: 659 IVIRKLDRESLTRYQLILKAEDTG--GLSSSATVNIKVTDINDKNPEFEASTLPYVFQVE 716

Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758
                 ++G + A D DEG NA + YSI        F++    G    E++T  +LDYE 
Sbjct: 717 EGKAQASVGVVHATDADEGINAEITYSI---PTDIPFTINATSG----EILTAKELDYEQ 769

Query: 759 PRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN--NYKDCFPVGPF 813
              +Y+ V+ A   A         V ++V D+ D  P   D +I  +    ++ F V   
Sbjct: 770 -LNEYKFVVTAKDGAPDARLGTASVTVMVLDLPDEVPKFSDARIDVHIPENEENFLV--- 825

Query: 814 GRVPAYDADVTDKLQYRILSGNNANLILLNETTGSM 849
             V A+D D   ++ Y +L   NA L  ++E +G +
Sbjct: 826 ATVQAFDPDSMPEITY-VLRKGNAELFKVSEKSGEV 860



 Score =  183 bits (446), Expect = 5e-44
 Identities = 188/700 (26%), Positives = 306/700 (43%), Gaps = 72/700 (10%)

Query: 29   EASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQD 88
            E SV  G ++          +  + + AE+  T+ +V A+  +PE+              
Sbjct: 590  EVSVTPGPNTKPPRFQKPIYEVQVSEGAEINSTVTVVHAE--DPENDAVVYSIISGNDLR 647

Query: 89   VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
             F +   SG ++    LDRE + RY +++KA D        LSS+AT+++ + D ND  P
Sbjct: 648  QFAVGQESGVIIVIRKLDRESLTRYQLILKAEDTGG-----LSSSATVNIKVTDINDKNP 702

Query: 149  QFSEKT--YTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206
            +F   T  Y   V+E  +      +  + ATDAD G N+ I Y+I    T + F+I++ S
Sbjct: 703  EFEASTLPYVFQVEEGKAQAS---VGVVHATDADEGINAEITYSI---PTDIPFTINATS 756

Query: 207  GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266
            G++   K LDYEQ+  Y+ V+ A+DG   +R  T  + + + D+ D  P+F  +     +
Sbjct: 757  GEILTAKELDYEQLNEYKFVVTAKDGAPDARLGTASVTVMVLDLPDEVPKFSDARIDVHI 816

Query: 267  SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326
             EN    + +  VQA+D D     E+TY +      GN +L   +  +SG V T   LD 
Sbjct: 817  PENEE-NFLVATVQAFDPDS--MPEITYVLR----KGNAEL-FKVSEKSGEVRTIKGLDY 868

Query: 327  ETQAKYQLLV-TATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
            E+Q ++QL + T  + G+ P   T                F+     V + +D+  GT +
Sbjct: 869  ESQKQHQLTIGTIENDGNGP-GDTILLVVDVEDRNDLPPRFITVPDPVTVNDDQGIGTII 927

Query: 386  VTLTATDAD---EDNRLHYEITG-GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441
             TL A D D     N + YEI G G     F +      G + +   L  +++  Y + +
Sbjct: 928  ATLPAIDGDGTSPGNVVRYEIVGRGKAPKYFQVDPDT--GAVRIRDELRKEEDTEYQVDI 985

Query: 442  SATDSG--GRSDTAMVQINI---TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496
             A D G    S  A +++++     + N     +N   + +      IG      S T S
Sbjct: 986  RAYDLGEPQLSSVAPLRVDVHHLLSSGNNEIKLDNKLESGTGMSSESIGLAFSDDSYTTS 1045

Query: 497  -----DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL-----------LD 540
                 +     ++   ++S+ S +       +FV     G    +             LD
Sbjct: 1046 VPESMEANSTLKLIQIVNSKTSGDGPPAFRCEFVSGNGGGIFNLSSADHGCNLLLIQPLD 1105

Query: 541  RETMSGY--LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF-------KQQLYTANIM 591
             E  S Y   L +T+    V  L DTT VEI V D NDN P F       +Q  +   + 
Sbjct: 1106 FENKSSYSLQLRLTSHRYFVNPLKDTTSVEIIVQDENDNAPEFEFNRLRGQQDTFYTVVT 1165

Query: 592  EDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDR---EEGSFVIDPASGVIRTNKALD 646
            E+  V T++ QV ATD D G  G + Y L  D ++R       F++   +GV+RT K   
Sbjct: 1166 EEMDVDTTILQVRATDRDSGKFGTVRYTLYDDDENRVNMPTSFFMMSEDTGVLRTAKHFK 1225

Query: 647  RES--VATHDLKAVAIDG---GTPPQSSTVIVHIKIEDIN 681
             E+    T  ++A   DG   G+    + ++V+ K+ DIN
Sbjct: 1226 NENDFPLTFLVEARDSDGQEQGSHRTRARIVVN-KLADIN 1264



 Score =  156 bits (379), Expect = 7e-36
 Identities = 188/742 (25%), Positives = 319/742 (42%), Gaps = 75/742 (10%)

Query: 90   FRIDGRSGALLTRASLDREKVA--RYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
            F + G    ++   +LDR+  A  R+   V A +   P ++  S+  ++ V++ D NDN 
Sbjct: 441  FNVTGDGILVVNEENLDRDPPAPGRFKFQVVARE---PRTNAASAPLSLTVHLRDVNDNA 497

Query: 148  PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI--IGGNTQMQFSIDSL 205
            P+ +     +S+      +++ ++ ++ ATD D G N+ + Y+I  +  N   +F+I++ 
Sbjct: 498  PKLA-MVAPISITAG-DQSESRLVTQVTATDNDEGPNAVVTYSIYHVSNNGIQKFTINAT 555

Query: 206  SGDVSLV-KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
            +G++    + L  EQ   Y + ++A D G  S     ++ +     N   PRF   +++ 
Sbjct: 556  TGEIRTQGRLLAGEQ---YSITVQATDIGGLSSQAIVEVSVT-PGPNTKPPRFQKPIYEV 611

Query: 265  SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
             VSE   I  ++  V A D +   N  + Y++     +GN      +   SG +    +L
Sbjct: 612  QVSEGAEINSTVTVVHAEDPE---NDAVVYSII----SGNDLRQFAVGQESGVIIVIRKL 664

Query: 325  DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
            DRE+  +YQL++ A D G    SAT                     Y  ++ E +   + 
Sbjct: 665  DRESLTRYQLILKAEDTGGLSSSATVNIKVTDINDKNPEFEASTLPYVFQVEEGKAQAS- 723

Query: 385  VVTLTATDADEDNRLHYEITGG-NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443
            V  + ATDADE   ++ EIT    T   F+I + +G   I  A+ LD++Q   Y   V+A
Sbjct: 724  VGVVHATDADEG--INAEITYSIPTDIPFTINATSGE--ILTAKELDYEQLNEYKFVVTA 779

Query: 444  TDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501
             D     R  TA V + + D  +  P F +A     + E+      V  V A D D    
Sbjct: 780  KDGAPDARLGTASVTVMVLDLPDEVPKFSDARIDVHIPENEE-NFLVATVQAFDPDS--M 836

Query: 502  AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL 561
             +ITY L           + + F ++ ++G + T K LD E+   + LT+   +      
Sbjct: 837  PEITYVLRKG--------NAELFKVSEKSGEVRTIKGLDYESQKQHQLTIGTIENDGNGP 888

Query: 562  SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI-HYEL 620
             DT  + + V D ND  P F        + +D  +GT ++ + A D D    G +  YE+
Sbjct: 889  GDTILLVVDVEDRNDLPPRFITVPDPVTVNDDQGIGTIIATLPAIDGDGTSPGNVVRYEI 948

Query: 621  DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST----VIVH-- 674
              + +    F +DP +G +R    L +E    + +   A D G P  SS     V VH  
Sbjct: 949  VGRGKAPKYFQVDPDTGAVRIRDELRKEEDTEYQVDIRAYDLGEPQLSSVAPLRVDVHHL 1008

Query: 675  -------IKIEDINDSPP---------VFESDCLTFYISENSPIGTT---IGEIRAHDPD 715
                   IK+++  +S            F  D  T  + E+    +T   I  + +    
Sbjct: 1009 LSSGNNEIKLDNKLESGTGMSSESIGLAFSDDSYTTSVPESMEANSTLKLIQIVNSKTSG 1068

Query: 716  EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---- 771
            +GP A        G+    F+L +        L+ +  LD+E+ +  Y L +R  S    
Sbjct: 1069 DGPPA-FRCEFVSGNGGGIFNLSS--ADHGCNLLLIQPLDFEN-KSSYSLQLRLTSHRYF 1124

Query: 772  -PPLWNDVRVEILVTDVNDNAP 792
              PL +   VEI+V D NDNAP
Sbjct: 1125 VNPLKDTTSVEIIVQDENDNAP 1146



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 61/252 (24%), Positives = 108/252 (42%), Gaps = 35/252 (13%)

Query: 645 LDR-ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703
           LDR E   +H +  V+    +  +  T+ + +++ DIND+ P F +      + E++P+G
Sbjct: 99  LDRDEENLSHIVFQVSCTTRSTGKKRTIPIIVRVSDINDNAPRFMNTPYEVTVPESTPVG 158

Query: 704 TTI-GEIRAHDPDEGPNAVVHYSI-KGGDDSNSFSLETRQG--------SDKAELVTMVD 753
           TTI   I+A D D G N +V Y I +G  +S +    +  G          + ++     
Sbjct: 159 TTIFRNIQALDKDAGVNGLVEYFIAEGSPNSTNVEKYSADGYGTFAISFPHQGQVTVAKT 218

Query: 754 LDYESPRKKYELVI-----RAASPPLWNDVRVEILVTDVNDNAP-------VMKDFQIIF 801
           LD+E  +  Y  ++     R  +  L +   + + + D ND  P       V  D   I 
Sbjct: 219 LDFEKIQTYYLTIVASDRARNTADRLSSTTTLTVNIADSNDLDPSFIYSGCVSLDGACIN 278

Query: 802 NNYKDCFPVGPF--------GRVPAYDAD-VTDKLQYRILSG---NNANLILLNETTGSM 849
             Y    P G           R+ A D D +   ++Y   SG   N A+   ++E+TG +
Sbjct: 279 PEYSASVPAGSLLGVLTVLPERIQAVDLDTINSPIRYSFASGMPGNYADYFQIDESTGVL 338

Query: 850 TLSPQLNTNVPK 861
             +  ++T+  K
Sbjct: 339 KQTKAVDTSTAK 350



 Score = 45.2 bits (102), Expect = 0.026
 Identities = 44/176 (25%), Positives = 81/176 (46%), Gaps = 20/176 (11%)

Query: 99   LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQF-------S 151
            LL    LD E  + Y++ ++ T     V+  L  T ++ + + D+NDN P+F        
Sbjct: 1098 LLLIQPLDFENKSSYSLQLRLTSHRYFVNP-LKDTTSVEIIVQDENDNAPEFEFNRLRGQ 1156

Query: 152  EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG---GNTQMQFSIDSLSGD 208
            + T+   V E++ V  +  I +++ATD D G    +RY +         M  S   +S D
Sbjct: 1157 QDTFYTVVTEEMDV--DTTILQVRATDRDSGKFGTVRYTLYDDDENRVNMPTSFFMMSED 1214

Query: 209  VSLVKTLDY---EQVRSYRLVIRAQDG-GSPSRSNTT--QLLIN-IRDVNDNAPRF 257
              +++T  +   E       ++ A+D  G    S+ T  ++++N + D+N  A  F
Sbjct: 1215 TGVLRTAKHFKNENDFPLTFLVEARDSDGQEQGSHRTRARIVVNKLADINRMALSF 1270


>UniRef50_O60245 Cluster: Protocadherin-7 precursor; n=52;
           Euteleostomi|Rep: Protocadherin-7 precursor - Homo
           sapiens (Human)
          Length = 1069

 Score =  245 bits (600), Expect = 1e-62
 Identities = 177/590 (30%), Positives = 282/590 (47%), Gaps = 35/590 (5%)

Query: 173 KIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVK-TLDYEQVRSYRLVIRAQD 231
           ++ A++   G N   R ++     Q+  + D       +VK  LD EQ  SY L +R +D
Sbjct: 225 RLDASEGGGGTNPGGRSSVF--ELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRD 282

Query: 232 GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE 291
           GG P RS+   L + I DVNDN+PRF  S+++  ++EN   G  I++++A D D GVN +
Sbjct: 283 GGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQ 342

Query: 292 LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
           + Y       T +V   + +D  SGW+    ++DRE   + +  V A D G PP++  AT
Sbjct: 343 IEYVFGAA--TESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKAT 400

Query: 352 XXXXXXXXXXXXXXF-------MPGQYEV-ELAEDEPPGTPVVTLTATDADE-DNRLHYE 402
                                 +P +  V  +AED    TP+  +  +D D+ +N +   
Sbjct: 401 VVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTC 460

Query: 403 ITGGNTRGRFSITS-----QNGRG-LITVAQPLDFKQERRYVLTVSATDSGGRSDTA--M 454
              G+   +    S     QN +   +  + PLD++  R + + + A DSG  S ++   
Sbjct: 461 TVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSKNS 520

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           + + + D N+  P+F  +       E+   G  V  V ATD+D G NA+I YSL S +  
Sbjct: 521 LIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMG 580

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
                    F I+P +G I  N +LDRE    Y   V A+D G+P L  +T V + V D 
Sbjct: 581 --------IFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADK 632

Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634
           NDN+P F Q ++T  + E+    + V  V   DAD G N  +   +   +     F I+ 
Sbjct: 633 NDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYI---EENNNIFSIEN 689

Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694
            +G I +  + DRE   T+  +  A+DGG PP+S+T  V + + D ND+ P         
Sbjct: 690 DTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNIS 749

Query: 695 Y--ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
           Y  +  +S + T +  + A D D+G NA ++YSI GG+    F ++   G
Sbjct: 750 YTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSG 799



 Score =  232 bits (567), Expect = 1e-58
 Identities = 171/566 (30%), Positives = 256/566 (45%), Gaps = 22/566 (3%)

Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381
           G LDRE +  Y+L +   DGGDPPRS+ A               F    YE +LAE+  P
Sbjct: 264 GALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAP 323

Query: 382 GTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL 439
           GTP++ L A D D   + ++ Y         R  +      G ++V   +D ++  +   
Sbjct: 324 GTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREEVNQLRF 383

Query: 440 TVSATDSGG--RSDTAMVQINITDANNYAPVFE-----NAPY---TASVFEDAPIGTTVL 489
           TV A D G   ++D A V +NI D N+  P  E       P     A+V ED  + T + 
Sbjct: 384 TVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIA 443

Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
           +V  +D D G N  +T ++  ++  +     D +   N +   + T+  LD E    + +
Sbjct: 444 LVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNV 503

Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
            + A D G PSLS    + + V D NDN P+F Q +      E+ + G  V+ V ATDAD
Sbjct: 504 VIVAVDSGSPSLSSKNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDAD 563

Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669
            G N  I Y LD      G F IDP SG I  N  LDRE    ++ K  A D G P    
Sbjct: 564 SGKNAEIAYSLD--SSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQG 621

Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729
           +  V +++ D ND+ P F  D  TFY+ EN    + +G +   D D+G NA +   I+  
Sbjct: 622 STTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIE-- 679

Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVND 789
           +++N FS+E   G+  + +    D ++++        +    PP      V + V D ND
Sbjct: 680 ENNNIFSIENDTGTIYSTM--SFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDEND 737

Query: 790 NAP-VMKDFQIIFNNYKDCFPVGP-FGRVPAYDAD--VTDKLQYRILSGNNANLILLNET 845
           NAP V     I +        V      V A D+D  +   L Y I+ GN   L  ++ T
Sbjct: 738 NAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPT 797

Query: 846 TGSMTLSPQLNTNVPKLATMEVSVTD 871
           +G ++L  +L      L  + V V D
Sbjct: 798 SGVVSLVGKLTQKHYGLHRLVVQVND 823



 Score =  227 bits (555), Expect = 3e-57
 Identities = 182/596 (30%), Positives = 262/596 (43%), Gaps = 57/596 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ + D ND+SP FE   YEA + E ++ GT +L L+A D D+G N ++EY     T   
Sbjct: 295 RVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATES- 353

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                           V+ + R+D  SG L     +DRE+V +    V A D+  P    
Sbjct: 354 ----------------VRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPK-- 395

Query: 130 LSSTATIHVNIIDDNDNYPQFSE--------KTYTVSVDEDISVTDNPVIAKIKATDADV 181
            +  AT+ +NI D+NDN P            K    +V ED+ V D P IA ++ +D D 
Sbjct: 396 -TDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLV-DTP-IALVQVSDRDQ 452

Query: 182 GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVK-------TLDYEQVRSYRLVIRAQDGGS 234
           G N  +   ++G             GD +  K        LDYE  R + +VI A D GS
Sbjct: 453 GENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGS 512

Query: 235 PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294
           PS S+   L++ + D NDN P F  S+ +    EN   G  +  V A DAD G NAE+ Y
Sbjct: 513 PSLSSKNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAY 572

Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354
           ++ D    G       IDP SG +  +  LDRE   +Y+  V A D G P    + T   
Sbjct: 573 SL-DSSVMG----IFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIV 627

Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSI 414
                      FM   +   + E+  P +PV  +T  DAD+       +        FSI
Sbjct: 628 QVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSI 687

Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVF--- 469
             +N  G I      D + +  Y   V A D G   RS TA V + + D N+ AP     
Sbjct: 688 --ENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLP 745

Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
           +N  YT  +   + + T V  V ATDSD GINA + YS+          +  + F I+P 
Sbjct: 746 KNISYTL-LPPSSNVRTVVATVLATDSDDGINADLNYSIVG-------GNPFKLFEIDPT 797

Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585
           +G ++    L ++    + L V   D G PS S TT V + V +   N      Q+
Sbjct: 798 SGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTVVHVFVNESVSNATAIDSQI 853



 Score =  220 bits (538), Expect = 4e-55
 Identities = 177/601 (29%), Positives = 274/601 (45%), Gaps = 39/601 (6%)

Query: 99  LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158
           L+ + +LDRE+   Y + ++  D   P     SS A + V I D NDN P+F +  Y   
Sbjct: 260 LIVKGALDREQRDSYELTLRVRDGGDPPR---SSQAILRVLITDVNDNSPRFEKSVYEAD 316

Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ---FSIDSLSGDVSLVKTL 215
           + E+ S    P++ +++A D DVG N  I Y + G  T+       +D  SG +S++  +
Sbjct: 317 LAEN-SAPGTPIL-QLRAADLDVGVNGQIEY-VFGAATESVRRLLRLDETSGWLSVLHRI 373

Query: 216 DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE--------SVS 267
           D E+V   R  + A+D G P +++   +++NI+D NDN P                 +V+
Sbjct: 374 DREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVA 433

Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDK---DYTGNVDLPITIDPRSGWVYTSGQL 324
           E+V +   I  VQ  D D+G N  +T T+            D     + +  +++TS  L
Sbjct: 434 EDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPL 493

Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
           D E   ++ +++ A D G P  S+  +              F     EV   E+  PG  
Sbjct: 494 DYEATREFNVVIVAVDSGSPSLSSKNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGER 553

Query: 385 VVTLTATDADEDNRLHYEIT-GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443
           V T+ ATDAD         +   +  G F+I   +G  L+     LD +Q  RY   V+A
Sbjct: 554 VATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTV--LDREQTDRYEFKVNA 611

Query: 444 TDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501
            D G      +  V + + D N+  P F    +T  V E+    + V +V+  D+D G N
Sbjct: 612 KDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRN 671

Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL 561
           A++  SL  E +N         F I   TG I +    DRE  + Y   V A DGG P  
Sbjct: 672 AEM--SLYIEENNNI-------FSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPR 722

Query: 562 SDTTDVEISVVDVNDNEPVF---KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618
           S T  V + V+D NDN P     K   YT  +   + V T V+ V ATD+D G+N  ++Y
Sbjct: 723 SATATVSLFVMDENDNAPTVTLPKNISYTL-LPPSSNVRTVVATVLATDSDDGINADLNY 781

Query: 619 ELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678
            +   +  +  F IDP SGV+     L ++    H L     D G P QS+T +VH+ + 
Sbjct: 782 SIVGGNPFK-LFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTVVHVFVN 840

Query: 679 D 679
           +
Sbjct: 841 E 841



 Score =  176 bits (429), Expect = 6e-42
 Identities = 138/473 (29%), Positives = 217/473 (45%), Gaps = 38/473 (8%)

Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480
           + V   LD +Q   Y LT+   D G   RS  A++++ ITD N+ +P FE + Y A + E
Sbjct: 260 LIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAE 319

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           ++  GT +L + A D DVG+N QI Y   +  + E+V    +   ++  +G ++    +D
Sbjct: 320 NSAPGTPILQLRAADLDVGVNGQIEYVFGA--ATESVR---RLLRLDETSGWLSVLHRID 374

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY--------TANIME 592
           RE ++    TV ARD G P  +D   V +++ D NDN P  + +           AN+ E
Sbjct: 375 REEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAE 434

Query: 593 DALVGTSVSQVGATDADVGLNG--------RIHYELDPKDREEGSFVIDPASGVIRTNKA 644
           D LV T ++ V  +D D G NG         + ++L P    EG    +     + T+  
Sbjct: 435 DVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ--NKKKYFLHTSTP 492

Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
           LD E+    ++  VA+D G+P  SS   + +K+ D ND+PP+F    +  Y  EN+  G 
Sbjct: 493 LDYEATREFNVVIVAVDSGSPSLSSKNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGE 552

Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764
            +  + A D D G NA + YS+    DS+   +      D  +++    LD E    +YE
Sbjct: 553 RVATVLATDADSGKNAEIAYSL----DSSVMGIFAID-PDSGDILVNTVLDREQT-DRYE 606

Query: 765 LVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY--KDCFPVGPFGRVPAY 819
             + A     P L     V + V D NDN P  K  Q +F  Y  ++  P  P G V   
Sbjct: 607 FKVNAKDKGIPVLQGSTTVIVQVADKNDNDP--KFMQDVFTFYVKENLQPNSPVGMVTVM 664

Query: 820 DADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
           DAD     +  +    N N+  +   TG++  +   +       T  V   DG
Sbjct: 665 DADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDG 717



 Score = 46.0 bits (104), Expect = 0.015
 Identities = 25/65 (38%), Positives = 33/65 (50%)

Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615
           G   S  D  + ++ V+D+NDN P F   + T  + E+  VGT      ATD D G NG 
Sbjct: 118 GPSQSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGI 177

Query: 616 IHYEL 620
             YEL
Sbjct: 178 ERYEL 182



 Score = 42.3 bits (95), Expect = 0.19
 Identities = 21/56 (37%), Positives = 30/56 (53%)

Query: 456 QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE 511
           Q+ + D N+  P F +   T +V E+ P+GT  L+ +ATD D G N    Y L  E
Sbjct: 130 QVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQE 185



 Score = 41.5 bits (93), Expect = 0.32
 Identities = 20/48 (41%), Positives = 25/48 (52%)

Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
           DIND+ P F S  LT  + EN P+GT      A D D G N +  Y +
Sbjct: 135 DINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYEL 182



 Score = 40.3 bits (90), Expect = 0.75
 Identities = 20/53 (37%), Positives = 27/53 (50%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
           Q+ VLD ND++P F       +V E    GT  L   ATD+D G+N    Y +
Sbjct: 130 QVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYEL 182


>UniRef50_Q174A5 Cluster: Cadherin; n=1; Aedes aegypti|Rep: Cadherin
           - Aedes aegypti (Yellowfever mosquito)
          Length = 1727

 Score =  245 bits (599), Expect = 2e-62
 Identities = 243/838 (28%), Positives = 372/838 (44%), Gaps = 87/838 (10%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTL-----KATDQDIGKNAEVEYTIELV 65
           I + D ND +P F    YE+ + E A   T V  L     +  D D G N     T +L 
Sbjct: 134 IIITDVNDETPTFRSHSYESEINENAQENTPVSFLGFSRNEVFDYDQGHNG----TFDLY 189

Query: 66  TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125
               L P +            +  F +  +   LL     D EKV      + A + A  
Sbjct: 190 ----LEPNNGLFEITPSRAVNEATFVLRVKDSTLL-----DYEKVKSMNFTIHAREIAP- 239

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG--A 183
             +   S ATI V+I D NDN+P+FS+ +Y   + E+  V    ++ +I+A D D G   
Sbjct: 240 --EGKHSMATIVVHIRDQNDNFPEFSKASYECYLPENSGV--GALLTQIQAVDVDSGDFG 295

Query: 184 NSAIRYAIIGGNTQMQFSIDSLSGDVSLVK----TLDYEQVRSYRLVIRAQDGGSPSRSN 239
            S IR+  + G+     +++ L+G +++       LD E V+ + L I A+D       N
Sbjct: 296 TSGIRFISLSGSIADLLALNPLTGVITIKAPGGHALDRELVQKHYLTIEARDNLGRGNRN 355

Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGV-NAELTYTMT 297
           + QL+++I DVNDNAP F  S+++  + EN     + + ++A DAD  G  N+E+ + + 
Sbjct: 356 SVQLVVHILDVNDNAPVFLQSMYEARLMENKLSFETPLVLEARDADLNGTKNSEIKFEIV 415

Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRE--TQAKYQ-----LLVTATDGGDPPRSATA 350
           +  +  N     TID +SG +     +D E  T   +      L V A+D G P  S   
Sbjct: 416 EGQFKDN----FTIDAKSGKLVPLTPIDFELLTSGTFNIRPIFLTVLASDSGVPKLSTKV 471

Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGN 407
                          F+   Y   + E+ P G+P++ + A D D    +N + Y I  G 
Sbjct: 472 PVTIHVQDVNDHPPQFLHSVYTQSVPENLPSGSPILEVKAIDKDGSSPNNFIVYRIQSGA 531

Query: 408 TRGRFSITSQNGRGLITVAQPLD----FKQERRYVLTVSATDSG-GRSDT---AMVQINI 459
           +  +F I+   G   +     LD      +   Y L V A D G G         V I+I
Sbjct: 532 S-DKFVISPDTGIISVATGASLDPDMTDPKTTEYFLNVLALDGGIGEQQLQSFCRVNISI 590

Query: 460 TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG------INAQITYSLSSEIS 513
            D NN +P F   P T S+ E+ P+GT    + A D D        +++  + + S E +
Sbjct: 591 KDVNNKSPYFLE-PGTISIRENTPVGTYAYRLLANDLDKEPILRYYMDSNTSEARSEEGA 649

Query: 514 NEAVAHHDQ--QFVINPQTGAITTNKLLDRETMS----GYLLTVTARDGGVPSLSDTTDV 567
              ++ +D    F++N   G I   KLLDRE +     G+++   A + G  +   TT +
Sbjct: 650 LVKLSEYDYLTAFMLNSTDGLIRVIKLLDREKVEIIKLGFIVEDIAAEFGKQTA--TTTL 707

Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD-PKDRE 626
            I V D NDN P F+   Y  +I E++  G ++  V A D D   N  I Y L+ PK+  
Sbjct: 708 TIVVEDENDNNPKFRNSFYKRSIPENSPHGVTIMSVVADDMDK--NKTIRYSLEGPKEIT 765

Query: 627 EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686
           E    +D  +G I  +  +D E     +    A D G PP+SS   V I++ D ND+ P 
Sbjct: 766 E-LLHLDMETGEIVVSNKIDYEIFPWLNFTVRATDSGHPPRSSLAEVFIQVIDENDNNPY 824

Query: 687 FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746
           F  D   F + ENS IGT I  I+A DPD G    + Y I     S  FS++   G    
Sbjct: 825 FPIDTTNFTVYENSMIGTRIATIQALDPDSGAFGKITYLIDRVSASGKFSIDPDTG---- 880

Query: 747 ELVTMVDLDYESPRKKYELVIRA--------ASPPLWNDVR-VEILVTDVNDNAPVMK 795
            L+ + D      +  Y +VI A         S    N  + + I V D NDNAP+++
Sbjct: 881 -LLVVADFLDREKQDSYMIVIEAWDNYQFGYLSGESRNAFKQIFISVLDENDNAPIIQ 937



 Score =  233 bits (570), Expect = 5e-59
 Identities = 244/902 (27%), Positives = 386/902 (42%), Gaps = 90/902 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + V D  D  P F +      V E A  GTTV  +KA D D G N  + Y+I        
Sbjct: 22  VKVKDVEDQPPEFIVASTVIRVPEDAPIGTTVTQVKAIDGDRGVNNRIRYSIS------- 74

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKV-----ARYTVLVKATDQASP 125
                          +   FRIDG  G + T   LDRE       A Y + + AT+Q S 
Sbjct: 75  -------------RNISSPFRIDGSLGTISTTMKLDREDARNRANAAYILEIVATEQNSK 121

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV----IAKIKATDADV 181
           +    S    I + I D ND  P F   +Y   ++E+ +  + PV     ++ +  D D 
Sbjct: 122 IKPTPSVRTEITIIITDVNDETPTFRSHSYESEINEN-AQENTPVSFLGFSRNEVFDYDQ 180

Query: 182 GANSAIRYAIIGGNTQMQFSIDSLSGDVSLV------KTLDYEQVRSYRLVIRAQDGGSP 235
           G N      +   N   + +      + + V        LDYE+V+S    I A++    
Sbjct: 181 GHNGTFDLYLEPNNGLFEITPSRAVNEATFVLRVKDSTLLDYEKVKSMNFTIHAREIAPE 240

Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295
            + +   ++++IRD NDN P F  + ++  + EN  +G  + ++QA D D G     T  
Sbjct: 241 GKHSMATIVVHIRDQNDNFPEFSKASYECYLPENSGVGALLTQIQAVDVDSGDFG--TSG 298

Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSG----QLDRETQAKYQLLVTATDGGDPPRSATAT 351
           +     +G++   + ++P +G +         LDRE   K+ L + A D        +  
Sbjct: 299 IRFISLSGSIADLLALNPLTGVITIKAPGGHALDRELVQKHYLTIEARDNLGRGNRNSVQ 358

Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD----EDNRLHYEITGGN 407
                         F+   YE  L E++      + L A DAD    +++ + +EI  G 
Sbjct: 359 LVVHILDVNDNAPVFLQSMYEARLMENKLSFETPLVLEARDADLNGTKNSEIKFEIVEGQ 418

Query: 408 TRGRFSITSQNGRGLITVAQPLDFK-------QERRYVLTVSATDSG--GRSDTAMVQIN 458
            +  F+I +++G+  +    P+DF+         R   LTV A+DSG    S    V I+
Sbjct: 419 FKDNFTIDAKSGK--LVPLTPIDFELLTSGTFNIRPIFLTVLASDSGVPKLSTKVPVTIH 476

Query: 459 ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAV 517
           + D N++ P F ++ YT SV E+ P G+ +L V A D D    N  I Y + S  S++ V
Sbjct: 477 VQDVNDHPPQFLHSVYTQSVPENLPSGSPILEVKAIDKDGSSPNNFIVYRIQSGASDKFV 536

Query: 518 AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV--PSLSDTTDVEISVVDVN 575
              D   +I+  TGA     + D +T + Y L V A DGG+    L     V IS+ DVN
Sbjct: 537 ISPDTG-IISVATGASLDPDMTDPKT-TEYFLNVLALDGGIGEQQLQSFCRVNISIKDVN 594

Query: 576 DNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD--REEG----- 628
           +  P F +   T +I E+  VGT   ++ A D D     R + + +  +   EEG     
Sbjct: 595 NKSPYFLEP-GTISIRENTPVGTYAYRLLANDLDKEPILRYYMDSNTSEARSEEGALVKL 653

Query: 629 -------SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP--PQSSTVIVHIKIED 679
                  +F+++   G+IR  K LDRE V    L  +  D       Q++T  + I +ED
Sbjct: 654 SEYDYLTAFMLNSTDGLIRVIKLLDREKVEIIKLGFIVEDIAAEFGKQTATTTLTIVVED 713

Query: 680 INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD-SNSFSLE 738
            ND+ P F +      I ENSP G TI  + A D D+  N  + YS++G  + +    L+
Sbjct: 714 ENDNNPKFRNSFYKRSIPENSPHGVTIMSVVADDMDK--NKTIRYSLEGPKEITELLHLD 771

Query: 739 TRQGSDKAELVTMVDLDYE-SPRKKYEL-VIRAASPPLWNDVRVEILVTDVNDNAPVMKD 796
              G    E+V    +DYE  P   + +    +  PP  +   V I V D NDN P    
Sbjct: 772 METG----EIVVSNKIDYEIFPWLNFTVRATDSGHPPRSSLAEVFIQVIDENDNNPYFPI 827

Query: 797 FQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQ 854
               F  Y++         + A D D     K+ Y I   + +    ++  TG + ++  
Sbjct: 828 DTTNFTVYENSMIGTRIATIQALDPDSGAFGKITYLIDRVSASGKFSIDPDTGLLVVADF 887

Query: 855 LN 856
           L+
Sbjct: 888 LD 889



 Score =  215 bits (526), Expect = 1e-53
 Identities = 241/915 (26%), Positives = 397/915 (43%), Gaps = 89/915 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +++LD ND++PVF    YEA + E   S  T L L+A D D+      E   E+V     
Sbjct: 361  VHILDVNDNAPVFLQSMYEARLMENKLSFETPLVLEARDADLNGTKNSEIKFEIVEGQ-- 418

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD-- 128
                            +D F ID +SG L+    +D E +   T  ++        SD  
Sbjct: 419  ---------------FKDNFTIDAKSGKLVPLTPIDFELLTSGTFNIRPIFLTVLASDSG 463

Query: 129  --RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA-NS 185
              +LS+   + +++ D ND+ PQF    YT SV E++  + +P++ ++KA D D  + N+
Sbjct: 464  VPKLSTKVPVTIHVQDVNDHPPQFLHSVYTQSVPENLP-SGSPIL-EVKAIDKDGSSPNN 521

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVK--TLDYE----QVRSYRLVIRAQDGGSPSRS- 238
             I Y I  G +  +F I   +G +S+    +LD +    +   Y L + A DGG   +  
Sbjct: 522  FIVYRIQSGASD-KFVISPDTGIISVATGASLDPDMTDPKTTEYFLNVLALDGGIGEQQL 580

Query: 239  -NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG------VNAE 291
             +  ++ I+I+DVN+ +P ++      S+ EN P+G    R+ A D D+       +++ 
Sbjct: 581  QSFCRVNISIKDVNNKSP-YFLEPGTISIRENTPVGTYAYRLLANDLDKEPILRYYMDSN 639

Query: 292  LTYTMTDKDYTGNVD-----LPITIDPRSGWVYTSGQLDRETQA--KYQLLVTATDGGDP 344
             +   +++     +          ++   G +     LDRE     K   +V        
Sbjct: 640  TSEARSEEGALVKLSEYDYLTAFMLNSTDGLIRVIKLLDREKVEIIKLGFIVEDIAAEFG 699

Query: 345  PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT 404
             ++AT T              F    Y+  + E+ P G  ++++ A D D++  + Y + 
Sbjct: 700  KQTATTTLTIVVEDENDNNPKFRNSFYKRSIPENSPHGVTIMSVVADDMDKNKTIRYSLE 759

Query: 405  GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDA 462
            G               G I V+  +D++       TV ATDSG   RS  A V I + D 
Sbjct: 760  GPKEITELLHLDME-TGEIVVSNKIDYEIFPWLNFTVRATDSGHPPRSSLAEVFIQVIDE 818

Query: 463  NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522
            N+  P F       +V+E++ IGT +  + A D D G   +ITY L   +S         
Sbjct: 819  NDNNPYFPIDTTNFTVYENSMIGTRIATIQALDPDSGAFGKITY-LIDRVSASG------ 871

Query: 523  QFVINPQTGAITTNKLLDRETMSGYLLTVTARDG------GVPSLSDTTDVEISVVDVND 576
            +F I+P TG +     LDRE    Y++ + A D          S +    + ISV+D ND
Sbjct: 872  KFSIDPDTGLLVVADFLDREKQDSYMIVIEAWDNYQFGYLSGESRNAFKQIFISVLDEND 931

Query: 577  NEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL--NGRIHYELDPKDREEGSFVIDP 634
            N P+ +       + E   +   +  + ATDAD     NG I +++      +  F+   
Sbjct: 932  NAPIIQVPDGCVQVTEFHDIREPLLVLKATDADDPKTGNGLIGFDIIDVAGSDIFFLRQK 991

Query: 635  ASGV--IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC- 691
              GV  I ++++L+      + L  +A D G+PP +    + I + D ND  P F S   
Sbjct: 992  ERGVAEIFSSRSLNN-FYGNYSLLIMARDEGSPPNTVNEKIDICVLDFNDHAPEFVSPSS 1050

Query: 692  -LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG--DDSNSFSLETRQGSDKAEL 748
             +T  I EN+ +GT I ++ A D D GPNA V Y  K        SFS++   GS    +
Sbjct: 1051 NITIRIPENATVGTMIIQVMARDNDIGPNAAVRYRFKPDPLGSFRSFSIDEDTGS----I 1106

Query: 749  VTMVDLDYESPRKKYELVIRA----ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY 804
               + LD E  +K +EL + A       PL +D+ + I V +VND  P     +I  N  
Sbjct: 1107 TLKLPLDRER-QKVHELRVEAYDQGIPTPLSSDLDLTIYVRNVNDYEPQFLVEEISVNFT 1165

Query: 805  KDCFPVGPFGRVP-AYDADVTDKLQ-------YRILSGNNANLILLNETTGSMTLSPQLN 856
            +   P     ++P   D D  D L        Y I+ GN      L+  +  +T++ +L+
Sbjct: 1166 EHARPGLERRQLPDTIDRDEVDDLDDPPTMVCYFIVYGNENGHFHLDPYSHILTVTKELD 1225

Query: 857  TNVPKLATMEVSVTD 871
                   T+ V  T+
Sbjct: 1226 RESRSNHTLVVKATE 1240



 Score =  191 bits (465), Expect = 3e-46
 Identities = 191/721 (26%), Positives = 310/721 (42%), Gaps = 71/721 (9%)

Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295
           + + T  LL+ ++DV D  P F  +     V E+ PIG ++ +V+A D D GVN  + Y+
Sbjct: 13  TNTGTAALLVKVKDVEDQPPEFIVASTVIRVPEDAPIGTTVTQVKAIDGDRGVNNRIRYS 72

Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE-----TQAKYQLLVTATDGGD---PPRS 347
           +     + N+  P  ID   G + T+ +LDRE       A Y L + AT+      P  S
Sbjct: 73  I-----SRNISSPFRIDGSLGTISTTMKLDREDARNRANAAYILEIVATEQNSKIKPTPS 127

Query: 348 ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL-----TATDADEDNRLHYE 402
                             F    YE E+ E+    TPV  L        D D+ +   ++
Sbjct: 128 VRTEITIIITDVNDETPTFRSHSYESEINENAQENTPVSFLGFSRNEVFDYDQGHNGTFD 187

Query: 403 ITGGNTRGRFSITSQNGRGLITV------AQPLDFKQERRYVLTVSATDSG--GRSDTAM 454
           +      G F IT        T       +  LD+++ +    T+ A +    G+   A 
Sbjct: 188 LYLEPNNGLFEITPSRAVNEATFVLRVKDSTLLDYEKVKSMNFTIHAREIAPEGKHSMAT 247

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD---SDVGINAQITYSLSSE 511
           + ++I D N+  P F  A Y   + E++ +G  +  + A D    D G +     SLS  
Sbjct: 248 IVVHIRDQNDNFPEFSKASYECYLPENSGVGALLTQIQAVDVDSGDFGTSGIRFISLSGS 307

Query: 512 ISNEAVAHHDQQFVINPQTGAITT----NKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567
           I++           +NP TG IT        LDRE +  + LT+ ARD       ++  +
Sbjct: 308 IAD--------LLALNPLTGVITIKAPGGHALDRELVQKHYLTIEARDNLGRGNRNSVQL 359

Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG--LNGRIHYELDPKDR 625
            + ++DVNDN PVF Q +Y A +ME+ L   +   + A DAD+    N  I +E+  + +
Sbjct: 360 VVHILDVNDNAPVFLQSMYEARLMENKLSFETPLVLEARDADLNGTKNSEIKFEI-VEGQ 418

Query: 626 EEGSFVIDPASGVIRTNKALDRESVATHD-------LKAVAIDGGTPPQSSTVIVHIKIE 678
            + +F ID  SG +     +D E + +         L  +A D G P  S+ V V I ++
Sbjct: 419 FKDNFTIDAKSGKLVPLTPIDFELLTSGTFNIRPIFLTVLASDSGVPKLSTKVPVTIHVQ 478

Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSL 737
           D+ND PP F     T  + EN P G+ I E++A D D   PN  + Y I+ G  S+ F +
Sbjct: 479 DVNDHPPQFLHSVYTQSVPENLPSGSPILEVKAIDKDGSSPNNFIVYRIQSG-ASDKFVI 537

Query: 738 ETRQGSDKAELVTMVDLDYESPR-KKYELVIRA-----ASPPLWNDVRVEILVTDVNDNA 791
               G         +D D   P+  +Y L + A         L +  RV I + DVN+ +
Sbjct: 538 SPDTGIISVATGASLDPDMTDPKTTEYFLNVLALDGGIGEQQLQSFCRVNISIKDVNNKS 597

Query: 792 PVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVTDKLQYRILSGNNANLILLNETTGSMT 850
           P   +   I  + ++  PVG +  R+ A D D    L+Y +    ++N        G++ 
Sbjct: 598 PYFLEPGTI--SIRENTPVGTYAYRLLANDLDKEPILRYYM----DSNTSEARSEEGALV 651

Query: 851 LSPQLNTNVPKLATMEVSVTDG-VNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFL 909
              + +     L    ++ TDG +  IK + +  V +I    ++  I       TA   L
Sbjct: 652 KLSEYD----YLTAFMLNSTDGLIRVIKLLDREKVEIIKLGFIVEDIAAEFGKQTATTTL 707

Query: 910 S 910
           +
Sbjct: 708 T 708



 Score =  190 bits (464), Expect = 4e-46
 Identities = 190/666 (28%), Positives = 295/666 (44%), Gaps = 62/666 (9%)

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           + TA + V + D  D  P+F   +  + V ED  +     + ++KA D D G N+ IRY+
Sbjct: 15  TGTAALLVKVKDVEDQPPEFIVASTVIRVPEDAPI--GTTVTQVKAIDGDRGVNNRIRYS 72

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-----YRLVIRAQDGGS---PSRSNTTQ 242
           I   N    F ID   G +S    LD E  R+     Y L I A +  S   P+ S  T+
Sbjct: 73  I-SRNISSPFRIDGSLGTISTTMKLDREDARNRANAAYILEIVATEQNSKIKPTPSVRTE 131

Query: 243 LLINIRDVNDNAPRF----YTSLFQESVSENVPIGY-SIVRVQAYDADEGVNAELTYTMT 297
           + I I DVND  P F    Y S   E+  EN P+ +    R + +D D+G N      + 
Sbjct: 132 ITIIITDVNDETPTFRSHSYESEINENAQENTPVSFLGFSRNEVFDYDQGHNGTFDLYLE 191

Query: 298 DKDYTGNVDLPITIDPRSG--WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355
             +    +     ++  +    V  S  LD E        + A +     + + AT    
Sbjct: 192 PNNGLFEITPSRAVNEATFVLRVKDSTLLDYEKVKSMNFTIHAREIAPEGKHSMATIVVH 251

Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS-I 414
                     F    YE  L E+   G  +  + A D D  +     I   +  G  + +
Sbjct: 252 IRDQNDNFPEFSKASYECYLPENSGVGALLTQIQAVDVDSGDFGTSGIRFISLSGSIADL 311

Query: 415 TSQNG-RGLITVAQP----LDFKQERRYVLTVSATDSGGRSDTAMVQ--INITDANNYAP 467
            + N   G+IT+  P    LD +  +++ LT+ A D+ GR +   VQ  ++I D N+ AP
Sbjct: 312 LALNPLTGVITIKAPGGHALDRELVQKHYLTIEARDNLGRGNRNSVQLVVHILDVNDNAP 371

Query: 468 VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV-AHHDQQFVI 526
           VF  + Y A + E+     T LV+ A D+D      +  + +SEI  E V       F I
Sbjct: 372 VFLQSMYEARLMENKLSFETPLVLEARDAD------LNGTKNSEIKFEIVEGQFKDNFTI 425

Query: 527 NPQTGAITTNKLLDRETMSG-------YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP 579
           + ++G +     +D E ++          LTV A D GVP LS    V I V DVND+ P
Sbjct: 426 DAKSGKLVPLTPIDFELLTSGTFNIRPIFLTVLASDSGVPKLSTKVPVTIHVQDVNDHPP 485

Query: 580 VFKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGV 638
            F   +YT ++ E+   G+ + +V A D D    N  I Y +  +      FVI P +G+
Sbjct: 486 QFLHSVYTQSVPENLPSGSPILEVKAIDKDGSSPNNFIVYRI--QSGASDKFVISPDTGI 543

Query: 639 I--RTNKALDRE----SVATHDLKAVAIDGGTPPQ--SSTVIVHIKIEDINDSPPVFESD 690
           I   T  +LD +        + L  +A+DGG   Q   S   V+I I+D+N+  P F  +
Sbjct: 544 ISVATGASLDPDMTDPKTTEYFLNVLALDGGIGEQQLQSFCRVNISIKDVNNKSPYF-LE 602

Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750
             T  I EN+P+GT    + A+D D+ P  ++ Y +    DSN+    + +G+    LV 
Sbjct: 603 PGTISIRENTPVGTYAYRLLANDLDKEP--ILRYYM----DSNTSEARSEEGA----LVK 652

Query: 751 MVDLDY 756
           + + DY
Sbjct: 653 LSEYDY 658



 Score =  137 bits (331), Expect = 5e-30
 Identities = 176/694 (25%), Positives = 284/694 (40%), Gaps = 64/694 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V+D ND++P F +     +V E +  GT + T++A D D G   ++ Y I+ V+A   
Sbjct: 813  IQVIDENDNNPYFPIDTTNFTVYENSMIGTRIATIQALDPDSGAFGKITYLIDRVSAS-- 870

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD--QASPVS- 127
                               F ID  +G L+    LDREK   Y ++++A D  Q   +S 
Sbjct: 871  -----------------GKFSIDPDTGLLVVADFLDREKQDSYMIVIEAWDNYQFGYLSG 913

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD--VGANS 185
            +  ++   I ++++D+NDN P        V V E   + + P++  +KATDAD     N 
Sbjct: 914  ESRNAFKQIFISVLDENDNAPIIQVPDGCVQVTEFHDIRE-PLLV-LKATDADDPKTGNG 971

Query: 186  AIRYAIIG-GNTQMQFSIDSLSGDVSLVKTLDYEQVR-SYRLVIRAQDGGSPSRSNTTQL 243
             I + II    + + F      G   +  +        +Y L+I A+D GSP  +   ++
Sbjct: 972  LIGFDIIDVAGSDIFFLRQKERGVAEIFSSRSLNNFYGNYSLLIMARDEGSPPNTVNEKI 1031

Query: 244  LINIRDVNDNAPRFYT--SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
             I + D ND+AP F +  S     + EN  +G  I++V A D D G NA + Y     D 
Sbjct: 1032 DICVLDFNDHAPEFVSPSSNITIRIPENATVGTMIIQVMARDNDIGPNAAVRYRFKP-DP 1090

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSATATXXXXXXXXX 360
             G+     +ID  +G +     LDRE Q  ++L V A D G P P S+            
Sbjct: 1091 LGSFR-SFSIDEDTGSITLKLPLDRERQKVHELRVEAYDQGIPTPLSSDLDLTIYVRNVN 1149

Query: 361  XXXXXFMPGQYEVELAEDEPPGTPVVTLTAT-DADEDNRLHYEITGGNTRGRFSITSQNG 419
                 F+  +  V   E   PG     L  T D DE +    ++    T   + I   N 
Sbjct: 1150 DYEPQFLVEEISVNFTEHARPGLERRQLPDTIDRDEVD----DLDDPPTMVCYFIVYGNE 1205

Query: 420  RGLITVAQPLDFKQERRYVLTVSAT-DSGGRSDTAMVQINITDANNYAPVFE-NAPYTAS 477
             G   +  P        ++LTV+   D   RS+  +V     D  N  P    + P   +
Sbjct: 1206 NGHFHL-DPYS------HILTVTKELDRESRSNHTLVVKATEDCINTPPSINLSRPEAIA 1258

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            + +  P          T +       I        S +          I+ + GA++   
Sbjct: 1259 LQKPTPFKYHQRTTKPTTAVASQYVSIYDRYKKSRSFDTPGTE-----IDIKQGAVSWQS 1313

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVE--ISVVDVNDNEPVFKQQLYTANIMEDAL 595
              D    S  +       G +   +D T V   I V D+NDN PVF Q+++T  +    +
Sbjct: 1314 DADSAPSSLLMPRFEKYTGQLFYHNDNTLVRVLIHVQDINDNPPVFIQKIFTGGVTTSTV 1373

Query: 596  VGTSVSQVGATDADVGLNGRI-HYELD--PKDREEG-------SFVIDPASGVIRTNKAL 645
             GT   ++ A D D G NG++ +Y++    K   EG        F++D  +G ++ N   
Sbjct: 1374 FGTQFLKLTAIDRDHGANGQVSYYQIGDIKKTLTEGLENVQKPPFLVDRRTGAVQLNFDP 1433

Query: 646  DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679
             +      D K +A D       + V +++  ED
Sbjct: 1434 QKGMKGYFDFKVLANDSAGHSDEAHVFIYLLRED 1467



 Score = 72.5 bits (170), Expect = 2e-10
 Identities = 67/239 (28%), Positives = 111/239 (46%), Gaps = 29/239 (12%)

Query: 2    SVPFCIHQQIN--VLDCNDHSPVFEMQQYEASVR--EGASSGTTVLTLKATDQDIGKNAE 57
            S P  ++++I+  VLD NDH+P F       ++R  E A+ GT ++ + A D DIG NA 
Sbjct: 1022 SPPNTVNEKIDICVLDFNDHAPEFVSPSSNITIRIPENATVGTMIIQVMARDNDIGPNAA 1081

Query: 58   VEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLV 117
            V Y  +        P+                F ID  +G++  +  LDRE+   + + V
Sbjct: 1082 VRYRFK--------PDPLGSFRS---------FSIDEDTGSITLKLPLDRERQKVHELRV 1124

Query: 118  KATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE----DISVTDNP-VIA 172
            +A DQ  P    LSS   + + + + ND  PQF  +  +V+  E     +     P  I 
Sbjct: 1125 EAYDQGIPTP--LSSDLDLTIYVRNVNDYEPQFLVEEISVNFTEHARPGLERRQLPDTID 1182

Query: 173  KIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD 231
            + +  D D    + + Y I+ GN    F +D  S  +++ K LD E   ++ LV++A +
Sbjct: 1183 RDEVDDLD-DPPTMVCYFIVYGNENGHFHLDPYSHILTVTKELDRESRSNHTLVVKATE 1240



 Score = 44.0 bits (99), Expect = 0.061
 Identities = 47/173 (27%), Positives = 74/173 (42%), Gaps = 11/173 (6%)

Query: 455  VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS- 513
            V I++ D N+  PVF    +T  V      GT  L ++A D D G N Q++Y    +I  
Sbjct: 1345 VLIHVQDINDNPPVFIQKIFTGGVTTSTVFGTQFLKLTAIDRDHGANGQVSYYQIGDIKK 1404

Query: 514  --NEAVAH-HDQQFVINPQTGAITTNKLLDRETMSGYL-LTVTARDGGVPSLSDTTDVEI 569
               E + +     F+++ +TGA+  N    ++ M GY    V A D      SD   V I
Sbjct: 1405 TLTEGLENVQKPPFLVDRRTGAVQLN-FDPQKGMKGYFDFKVLANDSA--GHSDEAHVFI 1461

Query: 570  SVVDVNDNEPVFKQQLYTANIMEDALVGTSV-SQVGATDADVGLNGRIHYELD 621
             ++   D    F  +L    + E       V S V ++  ++  + RIH   D
Sbjct: 1462 YLLR-EDQRVKFVLRLQPTEVREKIFTFRDVLSNVSSSIVNID-DFRIHENRD 1512



 Score = 41.5 bits (93), Expect = 0.32
 Identities = 21/57 (36%), Positives = 32/57 (56%)

Query: 668  SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
            ++ V V I ++DIND+PPVF     T  ++ ++  GT   ++ A D D G N  V Y
Sbjct: 1340 NTLVRVLIHVQDINDNPPVFIQKIFTGGVTTSTVFGTQFLKLTAIDRDHGANGQVSY 1396


>UniRef50_UPI0000E81FAF Cluster: PREDICTED: similar to Protocadherin
           beta 1 precursor (PCDH-beta1); n=1; Gallus gallus|Rep:
           PREDICTED: similar to Protocadherin beta 1 precursor
           (PCDH-beta1) - Gallus gallus
          Length = 926

 Score =  244 bits (598), Expect = 2e-62
 Identities = 182/591 (30%), Positives = 276/591 (46%), Gaps = 29/591 (4%)

Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV----RSYRLVIRAQDGGSPSRSNT 240
           +A +  ++   ++  F +D  SG +++ +TLD E++     S  L+ +          N 
Sbjct: 143 AARKARVVSEGSEQHFRLDPHSGVLTVTETLDRERICPHSESCALLFKL------FFENP 196

Query: 241 TQLL---INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297
            QL+   + +RDVND++P F        +SE    G      +A D D G+N    Y+++
Sbjct: 197 VQLIRGEVEVRDVNDHSPVFPQKEMVLDISETASPGLRFPLEKAQDEDVGINGLQNYSLS 256

Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357
              +            +   +     LDRE Q +  L++TATDGG PPRS TA       
Sbjct: 257 PNSHFSLALGRGKDGDKYAELVLQRPLDREEQRELHLVLTATDGGSPPRSGTAQVRVVVL 316

Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSIT 415
                   F    YE+ +AE+ PPG  VV ++A D DE  + ++ Y  +    R R   +
Sbjct: 317 DANDNMPVFSREVYEIRVAENSPPGQLVVRVSAADPDEGSNGKVRYAFSQTTERTRQLFS 376

Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYT 475
              G G I V   LD +  + + + V ATD GG S    V + + D N+++P F      
Sbjct: 377 LDPGTGEIRVRGNLDCEDAKNHEMVVRATDGGGLSAHCRVHVEVRDVNDHSPEFPEKDVV 436

Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
             V E A  GT   + +A D DVGIN    YSLS   S+ ++A   ++     +   +  
Sbjct: 437 LDVPETASPGTRFPLEAARDKDVGINGLQDYSLSPN-SHFSLALETEKR--GGKYAELVL 493

Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
            K LDRE      L +TA DGG PS S T  V + V+D NDN PVF +++Y   + E++ 
Sbjct: 494 QKPLDREEQRELHLVLTATDGGSPSRSGTAQVRVVVLDANDNMPVFSREVYEVRVAENSP 553

Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGS---FVIDPASGVIRTNKALDRESVAT 652
            G  V +V A D D G  G++ Y        EGS   F ++  SGVIR +  LD E   +
Sbjct: 554 PGQLVVRVSAADPDEGSYGKVRYAFS--QTTEGSRQLFDLNADSGVIRVSGKLDFEEAKS 611

Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
           H+L   A DGG    S+   VH+++ D+ND+ P      ++  I E++P  T +  +   
Sbjct: 612 HELVVRATDGGG--LSAHCRVHVEVLDVNDNAPEMALSSVSASIPEDAPPRTVVALLSVR 669

Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY 763
           D D G N     +I+G      FSL T   ++  EL T   LD E+    Y
Sbjct: 670 DRDSGDNGRTECAIEG---DVPFSL-TAAFANHYELRTSAALDRETTALGY 716



 Score =  225 bits (550), Expect = 1e-56
 Identities = 168/552 (30%), Positives = 257/552 (46%), Gaps = 46/552 (8%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           I  ++ V D NDHSPVF  ++    + E AS G      KA D+D+G N    Y      
Sbjct: 200 IRGEVEVRDVNDHSPVFPQKEMVLDISETASPGLRFPLEKAQDEDVGINGLQNY------ 253

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASP 125
             +L+P                    DG +   L+ +  LDRE+     +++ ATD  SP
Sbjct: 254 --SLSPNSHFSLALGRGK--------DGDKYAELVLQRPLDREEQRELHLVLTATDGGSP 303

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
                S TA + V ++D NDN P FS + Y + V E  +     ++ ++ A D D G+N 
Sbjct: 304 PR---SGTAQVRVVVLDANDNMPVFSREVYEIRVAE--NSPPGQLVVRVSAADPDEGSNG 358

Query: 186 AIRYAI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
            +RYA       T+  FS+D  +G++ +   LD E  +++ +V+RA DGG  S     ++
Sbjct: 359 KVRYAFSQTTERTRQLFSLDPGTGEIRVRGNLDCEDAKNHEMVVRATDGGGLSAH--CRV 416

Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
            + +RDVND++P F        V E    G       A D D G+N    Y+++   +  
Sbjct: 417 HVEVRDVNDHSPEFPEKDVVLDVPETASPGTRFPLEAARDKDVGINGLQDYSLSPNSH-- 474

Query: 304 NVDLPITIDPRSG---WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
              L +  + R G    +     LDRE Q +  L++TATDGG P RS TA          
Sbjct: 475 -FSLALETEKRGGKYAELVLQKPLDREEQRELHLVLTATDGGSPSRSGTAQVRVVVLDAN 533

Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN----RLHYEITGGNTRGRFSITS 416
                F    YEV +AE+ PPG  VV ++A D DE +    R  +  T   +R  F + +
Sbjct: 534 DNMPVFSREVYEVRVAENSPPGQLVVRVSAADPDEGSYGKVRYAFSQTTEGSRQLFDLNA 593

Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA 476
            +  G+I V+  LDF++ + + L V ATD GG S    V + + D N+ AP    +  +A
Sbjct: 594 DS--GVIRVSGKLDFEEAKSHELVVRATDGGGLSAHCRVHVEVLDVNDNAPEMALSSVSA 651

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
           S+ EDAP  T V ++S  D D G N +   ++  ++     A     +        + T+
Sbjct: 652 SIPEDAPPRTVVALLSVRDRDSGDNGRTECAIEGDVPFSLTAAFANHY-------ELRTS 704

Query: 537 KLLDRETMS-GY 547
             LDRET + GY
Sbjct: 705 AALDRETTALGY 716



 Score =  223 bits (546), Expect = 4e-56
 Identities = 186/605 (30%), Positives = 276/605 (45%), Gaps = 40/605 (6%)

Query: 90  FRIDGRSGALLTRASLDREKVARYT---VLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146
           FR+D  SG L    +LDRE++  ++    L+      +PV           V + D ND+
Sbjct: 158 FRLDPHSGVLTVTETLDRERICPHSESCALLFKLFFENPVQ-----LIRGEVEVRDVNDH 212

Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIA--KIKATDADVGANSAIRYAIIGGNTQMQFSID- 203
            P F +K   +    DIS T +P +     KA D DVG N    Y++   N+    ++  
Sbjct: 213 SPVFPQKEMVL----DISETASPGLRFPLEKAQDEDVGINGLQNYSL-SPNSHFSLALGR 267

Query: 204 SLSGD----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259
              GD    + L + LD E+ R   LV+ A DGGSP RS T Q+ + + D NDN P F  
Sbjct: 268 GKDGDKYAELVLQRPLDREEQRELHLVLTATDGGSPPRSGTAQVRVVVLDANDNMPVFSR 327

Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319
            +++  V+EN P G  +VRV A D DEG N ++ Y  +    T       ++DP +G + 
Sbjct: 328 EVYEIRVAENSPPGQLVVRVSAADPDEGSNGKVRYAFSQT--TERTRQLFSLDPGTGEIR 385

Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE 379
             G LD E    ++++V ATDGG    SA                 F      +++ E  
Sbjct: 386 VRGNLDCEDAKNHEMVVRATDGGG--LSAHCRVHVEVRDVNDHSPEFPEKDVVLDVPETA 443

Query: 380 PPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQNGRGL---ITVAQPLDFKQER 435
            PGT      A D D   N L       N+    ++ ++   G    + + +PLD +++R
Sbjct: 444 SPGTRFPLEAARDKDVGINGLQDYSLSPNSHFSLALETEKRGGKYAELVLQKPLDREEQR 503

Query: 436 RYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
              L ++ATD G   RS TA V++ + DAN+  PVF    Y   V E++P G  V+ VSA
Sbjct: 504 ELHLVLTATDGGSPSRSGTAQVRVVVLDANDNMPVFSREVYEVRVAENSPPGQLVVRVSA 563

Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553
            D D G   ++ Y+ S            Q F +N  +G I  +  LD E    + L V A
Sbjct: 564 ADPDEGSYGKVRYAFSQTTEGSR-----QLFDLNADSGVIRVSGKLDFEEAKSHELVVRA 618

Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613
            DGG   LS    V + V+DVNDN P       +A+I EDA   T V+ +   D D G N
Sbjct: 619 TDGG--GLSAHCRVHVEVLDVNDNAPEMALSSVSASIPEDAPPRTVVALLSVRDRDSGDN 676

Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673
           GR    ++  D              +RT+ ALDRE+ A    ++ A    T P+  T+  
Sbjct: 677 GRTECAIE-GDVPFSLTAAFANHYELRTSAALDRETTALGYYRSEACH--TMPKKETLAA 733

Query: 674 HIKIE 678
           +  ++
Sbjct: 734 YAGVQ 738



 Score =  190 bits (464), Expect = 4e-46
 Identities = 129/378 (34%), Positives = 182/378 (48%), Gaps = 16/378 (4%)

Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480
           + + +PLD +++R   L ++ATD G   RS TA V++ + DAN+  PVF    Y   V E
Sbjct: 277 LVLQRPLDREEQRELHLVLTATDGGSPPRSGTAQVRVVVLDANDNMPVFSREVYEIRVAE 336

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           ++P G  V+ VSA D D G N ++ Y+ S     +      Q F ++P TG I     LD
Sbjct: 337 NSPPGQLVVRVSAADPDEGSNGKVRYAFS-----QTTERTRQLFSLDPGTGEIRVRGNLD 391

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
            E    + + V A DGG   LS    V + V DVND+ P F ++    ++ E A  GT  
Sbjct: 392 CEDAKNHEMVVRATDGG--GLSAHCRVHVEVRDVNDHSPEFPEKDVVLDVPETASPGTRF 449

Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV---IRTNKALDRESVATHDLKA 657
               A D DVG+NG   Y L P      +   +   G    +   K LDRE      L  
Sbjct: 450 PLEAARDKDVGINGLQDYSLSPNSHFSLALETEKRGGKYAELVLQKPLDREEQRELHLVL 509

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
            A DGG+P +S T  V + + D ND+ PVF  +     ++ENSP G  +  + A DPDEG
Sbjct: 510 TATDGGSPSRSGTAQVRVVVLDANDNMPVFSREVYEVRVAENSPPGQLVVRVSAADPDEG 569

Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWN 776
               V Y+     + +    +    +D   +     LD+E   K +ELV+RA     L  
Sbjct: 570 SYGKVRYAFSQTTEGSRQLFDL--NADSGVIRVSGKLDFEE-AKSHELVVRATDGGGLSA 626

Query: 777 DVRVEILVTDVNDNAPVM 794
             RV + V DVNDNAP M
Sbjct: 627 HCRVHVEVLDVNDNAPEM 644



 Score =  131 bits (317), Expect = 2e-28
 Identities = 115/400 (28%), Positives = 178/400 (44%), Gaps = 29/400 (7%)

Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY-- 547
           +V     D+G++     +  + + +E     +Q F ++P +G +T  + LDRE +  +  
Sbjct: 127 LVGNVAQDLGLSPSQLAARKARVVSEG---SEQHFRLDPHSGVLTVTETLDRERICPHSE 183

Query: 548 ---LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
              LL     +  V  +      E+ V DVND+ PVF Q+    +I E A  G       
Sbjct: 184 SCALLFKLFFENPVQLIRG----EVEVRDVNDHSPVFPQKEMVLDISETASPGLRFPLEK 239

Query: 605 ATDADVGLNGRIHYELDPKDREE---GSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
           A D DVG+NG  +Y L P        G          +   + LDRE      L   A D
Sbjct: 240 AQDEDVGINGLQNYSLSPNSHFSLALGRGKDGDKYAELVLQRPLDREEQRELHLVLTATD 299

Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
           GG+PP+S T  V + + D ND+ PVF  +     ++ENSP G  +  + A DPDEG N  
Sbjct: 300 GGSPPRSGTAQVRVVVLDANDNMPVFSREVYEIRVAENSPPGQLVVRVSAADPDEGSNGK 359

Query: 722 VHYSIKGGDDSNS--FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDV 778
           V Y+     +     FSL+   G    E+    +LD E   K +E+V+RA     L    
Sbjct: 360 VRYAFSQTTERTRQLFSLDPGTG----EIRVRGNLDCED-AKNHEMVVRATDGGGLSAHC 414

Query: 779 RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV-TDKLQ-YRILSGNN 836
           RV + V DVND++P   +  ++ +  +   P   F    A D DV  + LQ Y +   ++
Sbjct: 415 RVHVEVRDVNDHSPEFPEKDVVLDVPETASPGTRFPLEAARDKDVGINGLQDYSLSPNSH 474

Query: 837 ANLILLNETTG----SMTLSPQLNTNVPKLATMEVSVTDG 872
            +L L  E  G     + L   L+    +   + ++ TDG
Sbjct: 475 FSLALETEKRGGKYAELVLQKPLDREEQRELHLVLTATDG 514


>UniRef50_Q7QJ26 Cluster: ENSANGP00000009575; n=6; Culicidae|Rep:
            ENSANGP00000009575 - Anopheles gambiae str. PEST
          Length = 1424

 Score =  244 bits (597), Expect = 3e-62
 Identities = 359/1345 (26%), Positives = 556/1345 (41%), Gaps = 189/1345 (14%)

Query: 18   DHSPVF-EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAX 76
            +  P F E   Y+  ++E    GT VL + A DQD   N  +EY++     + +      
Sbjct: 13   NRKPTFNECDSYKPMLKEEQPVGTPVLHVNAIDQD--PNQIIEYSLMTTPGERVR----- 65

Query: 77   XXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYT---VLVKATDQASPVSDRLSST 133
                         FRID  +G + T    DR++  R     + V+ATD   P   RL   
Sbjct: 66   -------------FRIDKNTGEITTVHVFDRDEPIREKEIYISVRATDDGRP---RLDDV 109

Query: 134  ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG 193
             T+ V I+D NDN P F +  Y  SV +D+ V  N  +  I ATD D G NS I+Y ++ 
Sbjct: 110  CTLKVKIVDINDNSPVFDKVRYEESVAKDMKV--NQRVGTISATDMDDGDNSLIKYELLQ 167

Query: 194  GNTQMQF-SIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD---GGSPSRSNTTQLLINIRD 249
                  F  I+  +G V+LVK +D    + Y + +RA +    G P      ++ I + +
Sbjct: 168  SLPDSSFFQINENNGLVTLVKQIDRSPGQHYLIHVRAYNLNQQGEPVHHTDVEVKILVME 227

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA------ELTYTMTDKDYTG 303
             N  +P +++ L +E++  N         +  ++A+  +        EL    T++  + 
Sbjct: 228  SNKRSP-YFSKLPEETIVLNETFKDYSKPIAIFEANSAIPEKPEVIFELIQGRTEETNSK 286

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
            +  L   ++     +     LD E  A+Y L V+  +  D    A A             
Sbjct: 287  HTFLLEQLN-NVATIKLGKALDYEIIAEYTLTVSVKNSDD--LIAEAVLKIQVLDENDII 343

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQNGR 420
              F P      + E++PPGT V+ + A D D    +N + Y      ++  F I   N  
Sbjct: 344  PVF-PEMTSGAVLENDPPGTQVMVVKAYDLDGTPANNIVSYRFED-ESQHLFHI--DNIT 399

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSG-------GR--SDTAMVQINITDANNYAPVFEN 471
            G I     LD +Q   Y L V A D+        G+  S T ++ I + D N+  P F +
Sbjct: 400  GQIKTLAALDREQTDSYQLKVVAEDNSPSALYRNGKPNSITKLLFIKVMDKNDNKPAFTS 459

Query: 472  APYTAS-VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
              +    V ED  I T V+ V+A D D    + + Y++ S   NE +A     F I+  T
Sbjct: 460  QHFVVEGVPEDENINTPVIEVTARDPDA--TSLLHYTIVS--GNEGLA-----FKIDNNT 510

Query: 531  GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590
            G I+ N  LD ET+  Y L V   DG      D   V I V +VNDN P F   L    I
Sbjct: 511  GRISINNRLDYETVREYTLIVQVDDG---IFQDNATVSIKVKNVNDNPPRFTG-LRNVTI 566

Query: 591  MEDALVGTSVSQVGATDADV-GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES 649
             E+ +    +  V A D D+   +   H      D  + +  ID  SG +R  +ALDR+ 
Sbjct: 567  PEETIPSGCIMTVQAYDPDIENRSDPQHIRFFYVDEYDDAIEIDD-SGCLRLKRALDRDP 625

Query: 650  VATHD-----LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
                      + A   DG      +TVI  I +EDIND+ P   +     ++ EN P G 
Sbjct: 626  PLGSKRWQFIITATDEDGAGKKTPATVI--ISLEDINDNAPRLSNTMPVVWV-ENRPPGL 682

Query: 705  TIGEIRAHDPDEGPNAV-VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY 763
             + ++RA D DE  N    H+SI   D +  + ++ R      EL  +V+ D E  +K+Y
Sbjct: 683  IV-KLRADDVDEPQNGPPFHFSI---DPNARYEIKKRFKVQGEELHALVEFDREE-QKEY 737

Query: 764  EL--VIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD 820
            ++  +IR +   P+     + +++ D NDN       +I   NYK   P    GRV   D
Sbjct: 738  QIPILIRDSGEEPMSAVSMLHLVIGDDNDNKMRPGKSRIFVYNYKGESPNTEIGRVYVDD 797

Query: 821  ADVTDKLQYRILSGN-----NANLILLNETTGSMTLSPQLNTNVPKLA--TMEVSVTDGV 873
             D  D      +  +     +     LN  TG +T+         +L    +E S     
Sbjct: 798  PDDWDLPDKTFIWDDATRHQSVAFFDLNRDTGMITMLQGTRRGDYELNFHVIEHSRHFPR 857

Query: 874  NEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFI---DGLAAIIP----C 926
            + + A + ++V+ I EE +  S ++R +++TAE+F+S   G      D L A I      
Sbjct: 858  HNVTAKVTVTVKEIPEEAVDKSGSIRFHNVTAEEFVSRTPGQLTTPKDRLQASIANTLNV 917

Query: 927  PKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTL 986
             +EN+ +F+V    +  G  L+V FSA             SP+Y+P  L   +      L
Sbjct: 918  SRENVDVFTVLKRDNDNGTFLDVRFSAHG-----------SPYYAPERLNGMMGYQLHQL 966

Query: 987  ARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQC 1046
                 + VL    + C+ E       C    K           + L++   P+  +T   
Sbjct: 967  EEDVGLSVLMVGIDECIEEG----RNCELSCK-----------NTLYKSNVPIAVYTNT- 1010

Query: 1047 PEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQG-CSIDAAYTTAVCEL 1105
               F GVN      +A C       +C + S  +    GG L    CS    +    CE+
Sbjct: 1011 -SSFVGVNA---FVQAVC-------VCEAPSPSLTCLNGGFLVNDRCSCPEGFEGPHCEM 1059

Query: 1106 RARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNG--RYNER---HDFLALELV 1160
                F  S +  +P     +   + ++ + Q   GL++Y G   YN R    DFLALELV
Sbjct: 1060 LGIGFYGSGYALYPPTSPCNMTRISVELSPQQEDGLVMYIGPLNYNPRLPVPDFLALELV 1119

Query: 1161 SSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKVLS 1220
                   G P L   +  G G   I        G   TVEI    +TI MI+D+C   LS
Sbjct: 1120 K------GLPVLLLDY--GSGTIRIEHRHRFPQGKPFTVEIVLQPQTIEMIVDNCK--LS 1169

Query: 1221 LAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGG----LPNIPSSFQ- 1275
                        C +      P          +RFL++  PLQ+GG    L ++ S F  
Sbjct: 1170 -----------TCMSLDAPKGP----------NRFLNVNAPLQLGGAAVNLDSLGSLFNW 1208

Query: 1276 ---VKNKDFVGCISDFYIDHKFIDL 1297
                ++K F GC+ +  I+ +  DL
Sbjct: 1209 TYVPQDKGFSGCLRNLTINERTYDL 1233



 Score =  183 bits (446), Expect = 5e-44
 Identities = 195/732 (26%), Positives = 301/732 (41%), Gaps = 69/732 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ ++D ND+SPVF+  +YE SV +       V T+ ATD D G N+ ++Y +     D+
Sbjct: 113 KVKIVDINDNSPVFDKVRYEESVAKDMKVNQRVGTISATDMDDGDNSLIKYELLQSLPDS 172

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKA---TDQASPV 126
                               F+I+  +G +     +DR     Y + V+A     Q  PV
Sbjct: 173 ------------------SFFQINENNGLVTLVKQIDRSPGQHYLIHVRAYNLNQQGEPV 214

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
                +   + + +++ N   P FS+    T+ ++E       P IA  +A  A +    
Sbjct: 215 H---HTDVEVKILVMESNKRSPYFSKLPEETIVLNETFKDYSKP-IAIFEANSA-IPEKP 269

Query: 186 AIRYAIIGG-----NTQMQFSIDSLS--GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238
            + + +I G     N++  F ++ L+    + L K LDYE +  Y L +  ++  S    
Sbjct: 270 EVIFELIQGRTEETNSKHTFLLEQLNNVATIKLGKALDYEIIAEYTLTVSVKN--SDDLI 327

Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
               L I + D ND  P F   +   +V EN P G  ++ V+AYD D G  A    +   
Sbjct: 328 AEAVLKIQVLDENDIIPVF-PEMTSGAVLENDPPGTQVMVVKAYDLD-GTPANNIVSYRF 385

Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG-------GDPPRSATAT 351
           +D + ++     ID  +G + T   LDRE    YQL V A D           P S T  
Sbjct: 386 EDESQHL---FHIDNITGQIKTLAALDREQTDSYQLKVVAEDNSPSALYRNGKPNSITKL 442

Query: 352 XXXXXXXXXXXXXXFMPGQYEVE-LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG 410
                         F    + VE + EDE   TPV+ +TA D D  + LHY I  GN   
Sbjct: 443 LFIKVMDKNDNKPAFTSQHFVVEGVPEDENINTPVIEVTARDPDATSLLHYTIVSGNEGL 502

Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFE 470
            F I +  GR  I++   LD++  R Y L V   D G   D A V I + + N+  P F 
Sbjct: 503 AFKIDNNTGR--ISINNRLDYETVREYTLIVQ-VDDGIFQDNATVSIKVKNVNDNPPRFT 559

Query: 471 NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
                    E  P G  ++ V A D D+        S    I    V  +D    I+  +
Sbjct: 560 GLRNVTIPEETIPSG-CIMTVQAYDPDIE-----NRSDPQHIRFFYVDEYDDAIEID-DS 612

Query: 531 GAITTNKLLDRETMSG-----YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585
           G +   + LDR+   G     +++T T  DG       T  V IS+ D+NDN P     +
Sbjct: 613 GCLRLKRALDRDPPLGSKRWQFIITATDEDGAGKKTPAT--VIISLEDINDNAPRLSNTM 670

Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNG-RIHYELDPKDREEGSFVIDPASGVIRTNKA 644
               + E+   G  V ++ A D D   NG   H+ +DP  R E           +     
Sbjct: 671 PVVWV-ENRPPGLIV-KLRADDVDEPQNGPPFHFSIDPNARYEIKKRFKVQGEELHALVE 728

Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
            DRE    + +  +  D G  P S+  ++H+ I D ND+        +  Y  +     T
Sbjct: 729 FDREEQKEYQIPILIRDSGEEPMSAVSMLHLVIGDDNDNKMRPGKSRIFVYNYKGESPNT 788

Query: 705 TIGEIRAHDPDE 716
            IG +   DPD+
Sbjct: 789 EIGRVYVDDPDD 800



 Score = 99.5 bits (237), Expect = 1e-18
 Identities = 103/354 (29%), Positives = 153/354 (43%), Gaps = 23/354 (6%)

Query: 456 QINITDANNYAPVFENAP-YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           + +     N  P F     Y   + E+ P+GT VL V+A D D   N  I YSL +    
Sbjct: 5   EFSANQVENRKPTFNECDSYKPMLKEEQPVGTPVLHVNAIDQDP--NQIIEYSLMTT-PG 61

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETM---SGYLLTVTARDGGVPSLSDTTDVEISV 571
           E V     +F I+  TG ITT  + DR+         ++V A D G P L D   +++ +
Sbjct: 62  ERV-----RFRIDKNTGEITTVHVFDRDEPIREKEIYISVRATDDGRPRLDDVCTLKVKI 116

Query: 572 VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631
           VD+NDN PVF +  Y  ++ +D  V   V  + ATD D G N  I YEL     +   F 
Sbjct: 117 VDINDNSPVFDKVRYEESVAKDMKVNQRVGTISATDMDDGDNSLIKYELLQSLPDSSFFQ 176

Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAI----DGGTPPQSSTVIVHIKIEDINDSPPVF 687
           I+  +G++   K +DR S   H L  V        G P   + V V I + + N   P F
Sbjct: 177 INENNGLVTLVKQIDR-SPGQHYLIHVRAYNLNQQGEPVHHTDVEVKILVMESNKRSPYF 235

Query: 688 ES-DCLTFYISEN-SPIGTTIGEIRAHDPDEGPNAVVHYSIKG-GDDSNS-FSLETRQGS 743
                 T  ++E        I    A+        V+   I+G  +++NS  +    Q +
Sbjct: 236 SKLPEETIVLNETFKDYSKPIAIFEANSAIPEKPEVIFELIQGRTEETNSKHTFLLEQLN 295

Query: 744 DKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAPVMKD 796
           + A +     LDYE    +Y L +    S  L  +  ++I V D ND  PV  +
Sbjct: 296 NVATIKLGKALDYEI-IAEYTLTVSVKNSDDLIAEAVLKIQVLDENDIIPVFPE 348


>UniRef50_Q8MY75 Cluster: Pf1-cadherin; n=1; Ptychodera flava|Rep:
            Pf1-cadherin - Ptychodera flava
          Length = 1959

 Score =  244 bits (596), Expect = 4e-62
 Identities = 317/1262 (25%), Positives = 514/1262 (40%), Gaps = 156/1262 (12%)

Query: 377  EDEPPGTPVVTLTATDADEDNR-----LHYEI--TGGNTRGR--FSITSQNGRGLITVAQ 427
            E+  PG  V+T+ A D D+ N      + Y I     N+ G+  F+I S++   + T   
Sbjct: 579  ENGAPGVTVMTIQAEDLDDPNEGGNALVRYSILRNAQNSVGQAIFAIDSESAV-ITTQVG 637

Query: 428  PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
             LD ++   Y + V A D G  + T    I ++D N+  P F  A     + E+ P+ ++
Sbjct: 638  NLDREEIPSYDIVVKAVDGGAHTGTVTATIYVSDENDNPPEFPQAKSFVEISENVPVDSS 697

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG--AITTNKLLDRE-TM 544
            V  V A D DVGIN   +YS+ S    E       +   +P +G   +   K +D E   
Sbjct: 698  VFKVIAIDRDVGIN---SYSIISGNVGEKF-----RIETDPDSGYAIVKVAKKIDFELNE 749

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
            S ++LT+   D      + TT+++I V+D ND  P F Q  Y A   ED    T++  V 
Sbjct: 750  SKFVLTIEVDDS---KNTATTELDIRVMDANDEVPSFSQPRYLAEHPEDFAKWTTIGTVA 806

Query: 605  ATDADVGLN-GRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHD------- 654
            ATD D       I +E+   P+  +   F +  A+G +   K LDRE     D       
Sbjct: 807  ATDRDKSEKFSEIEFEVVRVPEFPDSSFFTVGSANGSVMAIKDLDREPYEDPDQIRENYI 866

Query: 655  LKAVAID-----GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
                A D      G    ++TV   + I D+ND+ P F     T  + EN+P G   G +
Sbjct: 867  FTVTATDNVRGQSGERRNTATVTFTVSITDVNDNAPEFLPG-YTLLVPENTPAGYEAGVV 925

Query: 710  RAHDPDEGPNA--VVHYSIKGGDDSNSFSLETRQG-SDKAELVTMVDLDYESPRKKYELV 766
               D D+  N     H  I      + F + +  G  D+  +V++ + D E+    Y  V
Sbjct: 926  EIIDRDDDSNGPPFTHRVIDDDGILSFFDVSSPIGVEDQLRVVSLEEFDREATPFYYIPV 985

Query: 767  IRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVT-- 824
            + +    +     + + + DVNDN P      I+  +YK   P    G V A D D+   
Sbjct: 986  VLSDKHGVSATQTLTVTIGDVNDNPPSPATKTILVYSYKGQIPRSAIGEVYAADEDIVKG 1045

Query: 825  DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884
            D + Y + +        +++ TG + +             +EV        I  ++ + V
Sbjct: 1046 DDISYTVTT--PIPQFSVDKDTGQIIIEENTKAGTYDF-KVEVDEKPWPPVICTVI-VEV 1101

Query: 885  RLITEEMLLNSITVRLNDMTAEQFL--SP-LLGFFIDGLAAIIPCPKENIYIFSVQDDTD 941
            + I EE + +S +VRL   +AE+F+  +P +   F D L  ++   KENI IFSV     
Sbjct: 1102 KDIPEEAVFSSGSVRLL-TSAEKFIRGTPSMKDRFHDILVDVLGAKKENIDIFSV----- 1155

Query: 942  VTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNI 1001
                 +NV     + D      G  SP+Y P  +  ++ L +  +     V       ++
Sbjct: 1156 -----INVPGEENQCDVRWSAHG--SPYYRPEKMNTQLLLAKDVIESQLGVSFGMVPIDM 1208

Query: 1002 CVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTK 1061
            C+ E       C            ++  +  F  +  +    C C     G     +  +
Sbjct: 1209 CLDEGICE-SSCTNYFNAITDPTIIDDGADTFVSVTTIQRAECVC-----GAK---LAPR 1259

Query: 1062 ASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCELRARSFPVSSFLTFPGL 1121
              C      + C +G QC+    G +    C  D  Y    CE  +R F  +SF  +P L
Sbjct: 1260 GPCA----SNPCLNGGQCIDTPSGYV----CQCDEKYGGPNCEDISRGFQSNSFAWYPPL 1311

Query: 1122 KRRHRIHLKLKFATQTTSGLLLYNG-----RYNERHDFLALELVSSEAGRGGGPGLRFSF 1176
             +       ++F T++  G++LYNG        +  DF+A+ELV      GG P  +   
Sbjct: 1312 SQCEETKTSIEFLTKSRDGIILYNGPIVPIDLGQPQDFMAIELV------GGKP--KLYM 1363

Query: 1177 SLGGGKSEITVEG-NVGDGSWHTVEIEYFNRTITMILDDCDK-VLSLAGAADFGLKYACA 1234
             LG G   +T++   + D  WHT+EI   ++ +  +LD C+  V++         +  C 
Sbjct: 1364 DLGSGMLPLTIDSPPLNDEKWHTLEIIRKSKHVEFVLDHCENAVITETERTSVSDESNC- 1422

Query: 1235 NFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLP-----NIPSSFQ-VKNKDFVGCISDF 1288
                     +    T   +RFL++  PLQ+GG+        P++F      DFVGCI + 
Sbjct: 1423 ---------KATDTTPGTNRFLNVNTPLQLGGIDMDSTYTYPNTFNFAPGGDFVGCIRNV 1473

Query: 1289 YIDHKFIDLNSYVADNGTLAGCPEKRSRC---SSAPCYNGAECSDLWDTYICDCKEGHTG 1345
              D K  DL +   +  +  GCP+    C       C NG   ++    Y C C  G  G
Sbjct: 1474 IQDGKVYDLGTPGREKNSEQGCPQTDLLCYVDGVYVCKNGLCVTESASVYTCVCDPGWGG 1533

Query: 1346 KDCADSTGPPWRFGGDGMLSFNPLLRPIQLPWLNALSI---RTRQRDAFVMSIQ------ 1396
            + C D   P + F  D  + ++     +   +++   I    T++ DA +M +Q      
Sbjct: 1534 EAC-DEELPSYDFLSDSYVIYDLEASLVSDKYMSDYQIMVGNTQEEDALLMHLQNVDGEE 1592

Query: 1397 -----LKSGLLHYSYN-GE-----TMYLPMATLSDGAWHRIEIKWLGTDISVTVD--YGL 1443
                 +K G     YN G+     ++ +   T++DG +H + +   G      VD   G+
Sbjct: 1593 YITMKMKEGNAFIEYNLGDPGMKYSLRVHNYTINDGNYHTVRLLRYGNIFRFEVDGGGGV 1652

Query: 1444 RTVLMPMLANKIQGQYI--GKILIGGLDTTAGLLASDVGFFEGCIQDVR-----IGTAQS 1496
            RTV     A  I  ++I   K +I G + +   +      + GC +D R     IG    
Sbjct: 1653 RTV---EKAQGIFKEFIPDPKSVIVGANVSLSEMRVLGDDYSGCAKDARISNSYIGFDGE 1709

Query: 1497 LLNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRV--GPQCVSACEL 1554
            +     V   V   C     C+LS C     CV +     C+C    V  G  CV   E 
Sbjct: 1710 IDGTIAVPNRVEKDCNI---CLLSPCIAPLVCVPTPSFYYCSCPGDLVFRGGACVK--EG 1764

Query: 1555 GP 1556
            GP
Sbjct: 1765 GP 1766



 Score =  175 bits (426), Expect = 1e-41
 Identities = 196/746 (26%), Positives = 307/746 (41%), Gaps = 73/746 (9%)

Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
           D    +  I++    DN  + +F++  Y  SV E+       V+   ++  A       +
Sbjct: 96  DAWKDSFNIYITKSGDNSEHLKFTQDRYEGSVLENSPA--GTVVYGFESISA-CSECDLV 152

Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
            Y+++G   + +F++++  G V++   + LD E   SY L + A    +   + TT LLI
Sbjct: 153 EYSLLGTGEE-KFNLENKDGIVTIQTNEVLDRESRASYNLTLVA--ASASLETETTDLLI 209

Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
            + DVNDNAP F     + +V E  P    +  V A D D G N ++ Y      YT   
Sbjct: 210 TVEDVNDNAPEFDPETCEVTVPEISPADAIVAYVHAVDPDAGKNGKVMY------YTDTN 263

Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA-----TXXXXXXXXX 360
           D+  ++ P +G V   G L  +   +Y L V A D G P   A+                
Sbjct: 264 DMTFSVHPDTGGVIIGGPLQAK---EYTLTVFARDRGKPSLEASTPGRVIITVTPVDQSL 320

Query: 361 XXXXXFMPG------------QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT 408
                  PG            + +V L ED P G+ V T+ A   D+ ++  + +     
Sbjct: 321 KFSSILGPGPVILQDDDEELPEIKVSLMEDAPKGSVVTTIKAPSNDKSSQYRF-LMNNPM 379

Query: 409 RGRFSITSQNGRGLITVAQPLDF--KQERRYVLTVSATD---SGGRSDTAMVQINITDAN 463
             RF +    G  ++T    +D    +E    +T    D      +    ++ I  ++ +
Sbjct: 380 NPRFHVQYYTGDIVLTGRLDIDAHPTEEINVGITKDFNDPLREAPKEQKVIITIIPSETD 439

Query: 464 NYAP---VFENAPYTAS--VFEDAPIGTTVLVVSATDSDVGI---NAQITYSLSSEISNE 515
             AP   V +     AS   F+      TV  V    S V        +T   + + SN 
Sbjct: 440 KPAPPNQVVKPRIRRASKPSFDQPSYEGTVEEVDGLASPVPAFVPREILTVRANGDPSNI 499

Query: 516 AV----AHHDQQFVINPQTGAITTNKLLDRETMSGYL--LTVTARDGGVPSLSDTTDVE- 568
                 A   + F I   +G I++ K LDRE   G +   TVTA +      + TT VE 
Sbjct: 500 QYRIQQAEFREDFAIGLTSGIISSRKHLDREDNKGQVREFTVTASNS-----AGTTSVEV 554

Query: 569 -ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD---VGLNGRIHYELDPKD 624
            I + DVNDN P F    Y  +  E+   G +V  + A D D    G N  + Y +    
Sbjct: 555 LIKIKDVNDNAPQFPYPPYIGSFPENGAPGVTVMTIQAEDLDDPNEGGNALVRYSILRNA 614

Query: 625 RE---EGSFVIDPASGVIRTNKA-LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680
           +    +  F ID  S VI T    LDRE + ++D+   A+DGG    + TV   I + D 
Sbjct: 615 QNSVGQAIFAIDSESAVITTQVGNLDREEIPSYDIVVKAVDGGA--HTGTVTATIYVSDE 672

Query: 681 NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR 740
           ND+PP F        ISEN P+ +++ ++ A D D G N+   YSI  G+    F +ET 
Sbjct: 673 NDNPPEFPQAKSFVEISENVPVDSSVFKVIAIDRDVGINS---YSIISGNVGEKFRIETD 729

Query: 741 QGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQII 800
             S  A +     +D+E    K+ L I            ++I V D ND  P     + +
Sbjct: 730 PDSGYAIVKVAKKIDFELNESKFVLTIEVDDSKNTATTELDIRVMDANDEVPSFSQPRYL 789

Query: 801 FNNYKDCFPVGPFGRVPAYDADVTDK 826
             + +D       G V A D D ++K
Sbjct: 790 AEHPEDFAKWTTIGTVAATDRDKSEK 815



 Score =  170 bits (413), Expect = 5e-40
 Identities = 175/612 (28%), Positives = 262/612 (42%), Gaps = 50/612 (8%)

Query: 148  PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN---SAIRYAIIGGNTQMQFSIDS 204
            P F + +Y  +V+E +    +PV A +      V AN   S I+Y I     +  F+I  
Sbjct: 458  PSFDQPSYEGTVEE-VDGLASPVPAFVPREILTVRANGDPSNIQYRIQQAEFREDFAIGL 516

Query: 205  LSGDVSLVKTLDYE----QVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260
             SG +S  K LD E    QVR +  V  +   G+ S     ++LI I+DVNDNAP+F   
Sbjct: 517  TSGIISSRKHLDREDNKGQVREF-TVTASNSAGTTS----VEVLIKIKDVNDNAPQFPYP 571

Query: 261  LFQESVSENVPIGYSIVRVQAYDAD---EGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317
             +  S  EN   G +++ +QA D D   EG NA + Y++              ID  S  
Sbjct: 572  PYIGSFPENGAPGVTVMTIQAEDLDDPNEGGNALVRYSILRNAQNSVGQAIFAIDSESAV 631

Query: 318  VYTS-GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376
            + T  G LDRE    Y ++V A DGG    + T T              F   +  VE++
Sbjct: 632  ITTQVGNLDREEIPSYDIVVKAVDGG--AHTGTVTATIYVSDENDNPPEFPQAKSFVEIS 689

Query: 377  EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITS--QNGRGLITVAQPLDFK-Q 433
            E+ P  + V  + A D D      Y I  GN   +F I +   +G  ++ VA+ +DF+  
Sbjct: 690  ENVPVDSSVFKVIAIDRDVGIN-SYSIISGNVGEKFRIETDPDSGYAIVKVAKKIDFELN 748

Query: 434  ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
            E ++VLT+   DS   + T +  I + DAN+  P F    Y A   ED    TT+  V+A
Sbjct: 749  ESKFVLTIEVDDSKNTATTEL-DIRVMDANDEVPSFSQPRYLAEHPEDFAKWTTIGTVAA 807

Query: 494  TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE-------TMSG 546
            TD D    ++    +  E+           F +    G++   K LDRE           
Sbjct: 808  TDRD---KSEKFSEIEFEVVRVPEFPDSSFFTVGSANGSVMAIKDLDREPYEDPDQIREN 864

Query: 547  YLLTVTARD-----GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
            Y+ TVTA D      G    + T    +S+ DVNDN P F    YT  + E+   G    
Sbjct: 865  YIFTVTATDNVRGQSGERRNTATVTFTVSITDVNDNAPEFLPG-YTLLVPENTPAGYEAG 923

Query: 602  QVGATDADVGLNGR--IHYELDPKDREEGSFVIDPASGV-----IRTNKALDRESVATHD 654
             V   D D   NG    H  +D  D     F +    GV     + + +  DRE+   + 
Sbjct: 924  VVEIIDRDDDSNGPPFTHRVID-DDGILSFFDVSSPIGVEDQLRVVSLEEFDREATPFYY 982

Query: 655  LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
            +  V  D      S+T  + + I D+ND+PP   +  +  Y  +     + IGE+ A D 
Sbjct: 983  IPVVLSD--KHGVSATQTLTVTIGDVNDNPPSPATKTILVYSYKGQIPRSAIGEVYAADE 1040

Query: 715  DEGPNAVVHYSI 726
            D      + Y++
Sbjct: 1041 DIVKGDDISYTV 1052



 Score =  161 bits (392), Expect = 2e-37
 Identities = 204/768 (26%), Positives = 321/768 (41%), Gaps = 88/768 (11%)

Query: 87  QDVFRIDGRSG--ALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDN 144
           ++ F ++ + G   + T   LDRE  A Y + + A   +       + T  + + + D N
Sbjct: 161 EEKFNLENKDGIVTIQTNEVLDRESRASYNLTLVAASASLE-----TETTDLLITVEDVN 215

Query: 145 DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS 204
           DN P+F  +T  V+V E IS  D  ++A + A D D G N  + Y        M FS+  
Sbjct: 216 DNAPEFDPETCEVTVPE-ISPAD-AIVAYVHAVDPDAGKNGKVMYYT--DTNDMTFSVHP 271

Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT--QLLINIRDVNDNAPRFYTSL- 261
            +G V +   L   Q + Y L + A+D G PS   +T  +++I +  V D + +F + L 
Sbjct: 272 DTGGVIIGGPL---QAKEYTLTVFARDRGKPSLEASTPGRVIITVTPV-DQSLKFSSILG 327

Query: 262 ---------------FQESVSENVPIGYSIVRVQAYDADEG------VNAELTYTMTDKD 300
                           + S+ E+ P G  +  ++A   D+       +N  +      + 
Sbjct: 328 PGPVILQDDDEELPEIKVSLMEDAPKGSVVTTIKAPSNDKSSQYRFLMNNPMNPRFHVQY 387

Query: 301 YTGNVDLP--ITIDPRS------GWVYTSGQLDRETQAKYQLLVT----ATDGGDPPRSA 348
           YTG++ L   + ID         G         RE   + ++++T     TD   PP   
Sbjct: 388 YTGDIVLTGRLDIDAHPTEEINVGITKDFNDPLREAPKEQKVIITIIPSETDKPAPPNQV 447

Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVE-LAEDEPPGTPVVTLTATDADEDNRLHYEITGGN 407
                            +     EV+ LA   P   P   LT     + + + Y I    
Sbjct: 448 VKPRIRRASKPSFDQPSYEGTVEEVDGLASPVPAFVPREILTVRANGDPSNIQYRIQQAE 507

Query: 408 TRGRFSITSQNGRGLITVAQPLDFKQERRYV--LTVSATDSGGRSDTAMVQINITDANNY 465
            R  F+I   +  G+I+  + LD +  +  V   TV+A++S G + +  V I I D N+ 
Sbjct: 508 FREDFAIGLTS--GIISSRKHLDREDNKGQVREFTVTASNSAG-TTSVEVLIKIKDVNDN 564

Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSD---VGINAQITYSLSSEISNEAVAHHDQ 522
           AP F   PY  S  E+   G TV+ + A D D    G NA + YS+     N        
Sbjct: 565 APQFPYPPYIGSFPENGAPGVTVMTIQAEDLDDPNEGGNALVRYSILRNAQNSV---GQA 621

Query: 523 QFVINPQTGAITTN-KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581
            F I+ ++  ITT    LDRE +  Y + V A DGG  + + T    I V D NDN P F
Sbjct: 622 IFAIDSESAVITTQVGNLDREEIPSYDIVVKAVDGG--AHTGTVTATIYVSDENDNPPEF 679

Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG--VI 639
            Q      I E+  V +SV +V A D DVG+N   +  +     E+     DP SG  ++
Sbjct: 680 PQAKSFVEISENVPVDSSVFKVIAIDRDVGINS--YSIISGNVGEKFRIETDPDSGYAIV 737

Query: 640 RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699
           +  K +D E   +  +  + +D      ++T  + I++ D ND  P F          E+
Sbjct: 738 KVAKKIDFELNESKFVLTIEVDDS--KNTATTELDIRVMDANDEVPSFSQPRYLAEHPED 795

Query: 700 SPIGTTIGEIRAHDPDEGPN-AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD--- 755
               TTIG + A D D+    + + + +    +    S  T  GS    ++ + DLD   
Sbjct: 796 FAKWTTIGTVAATDRDKSEKFSEIEFEVVRVPEFPDSSFFT-VGSANGSVMAIKDLDREP 854

Query: 756 YESP---RKKYELV------IRAASPPLWNDVRV--EILVTDVNDNAP 792
           YE P   R+ Y         +R  S    N   V   + +TDVNDNAP
Sbjct: 855 YEDPDQIRENYIFTVTATDNVRGQSGERRNTATVTFTVSITDVNDNAP 902



 Score =  151 bits (366), Expect = 3e-34
 Identities = 186/660 (28%), Positives = 284/660 (43%), Gaps = 70/660 (10%)

Query: 90   FRIDGRSGALLTRASLDRE----KVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145
            F I   SG + +R  LDRE    +V  +TV   A++ A   S        + + I D ND
Sbjct: 512  FAIGLTSGIISSRKHLDREDNKGQVREFTVT--ASNSAGTTS------VEVLIKIKDVND 563

Query: 146  NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD---VGANSAIRYAIIGG--NT--QM 198
            N PQF    Y  S  E+ +      +  I+A D D    G N+ +RY+I+    N+  Q 
Sbjct: 564  NAPQFPYPPYIGSFPENGA--PGVTVMTIQAEDLDDPNEGGNALVRYSILRNAQNSVGQA 621

Query: 199  QFSIDSLSGDVSL-VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF 257
             F+IDS S  ++  V  LD E++ SY +V++A DGG+   + T    I + D NDN P F
Sbjct: 622  IFAIDSESAVITTQVGNLDREEIPSYDIVVKAVDGGA--HTGTVTATIYVSDENDNPPEF 679

Query: 258  YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV--DLPITIDPRS 315
              +     +SENVP+  S+ +V A D D G+N   +Y++     +GNV     I  DP S
Sbjct: 680  PQAKSFVEISENVPVDSSVFKVIAIDRDVGIN---SYSI----ISGNVGEKFRIETDPDS 732

Query: 316  GW--VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373
            G+  V  + ++D E      +L    D  D   +AT                F   +Y  
Sbjct: 733  GYAIVKVAKKIDFELNESKFVLTIEVD--DSKNTATTELDIRVMDANDEVPSFSQPRYLA 790

Query: 374  ELAEDEPPGTPVVTLTATDADEDNR---LHYEIT---GGNTRGRFSITSQNGRGLITV-- 425
            E  ED    T + T+ ATD D+  +   + +E+           F++ S NG  +     
Sbjct: 791  EHPEDFAKWTTIGTVAATDRDKSEKFSEIEFEVVRVPEFPDSSFFTVGSANGSVMAIKDL 850

Query: 426  -AQPLDFKQERR--YVLTVSATD-----SGGRSDTAMV--QINITDANNYAPVFENAPYT 475
              +P +   + R  Y+ TV+ATD     SG R +TA V   ++ITD N+ AP F    YT
Sbjct: 851  DREPYEDPDQIRENYIFTVTATDNVRGQSGERRNTATVTFTVSITDVNDNAPEFLPG-YT 909

Query: 476  ASVFEDAPIGTTVLVVSATDSDVGINA-QITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
              V E+ P G    VV   D D   N    T+ +  +    +         +  Q   ++
Sbjct: 910  LLVPENTPAGYEAGVVEIIDRDDDSNGPPFTHRVIDDDGILSFFDVSSPIGVEDQLRVVS 969

Query: 535  TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
              +  DRE    Y + V   D     +S T  + +++ DVNDN P    +       +  
Sbjct: 970  LEE-FDREATPFYYIPVVLSD--KHGVSATQTLTVTIGDVNDNPPSPATKTILVYSYKGQ 1026

Query: 595  LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654
            +  +++ +V A D D+     I Y +     +   F +D  +G I      +     T+D
Sbjct: 1027 IPRSAIGEVYAADEDIVKGDDISYTVTTPIPQ---FSVDKDTGQIIIE---ENTKAGTYD 1080

Query: 655  LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI-GTTIGEIRAHD 713
             K    +   PP   TVIV +K  DI +   VF S  +    S    I GT   + R HD
Sbjct: 1081 FKVEVDEKPWPPVICTVIVEVK--DIPEE-AVFSSGSVRLLTSAEKFIRGTPSMKDRFHD 1137



 Score =  139 bits (337), Expect = 9e-31
 Identities = 151/553 (27%), Positives = 235/553 (42%), Gaps = 59/553 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVTA 67
            I + D ND++P F    Y  S  E  + G TV+T++A D D    G NA V Y+I     
Sbjct: 556  IKIKDVNDNAPQFPYPPYIGSFPENGAPGVTVMTIQAEDLDDPNEGGNALVRYSI----- 610

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR-ASLDREKVARYTVLVKATDQASPV 126
               N +++           Q +F ID  S  + T+  +LDRE++  Y ++VKA D  +  
Sbjct: 611  -LRNAQNSVG---------QAIFAIDSESAVITTQVGNLDREEIPSYDIVVKAVDGGAHT 660

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
                + TATI+V+  D+NDN P+F +    V + E++ V  +  + K+ A D DVG NS 
Sbjct: 661  G---TVTATIYVS--DENDNPPEFPQAKSFVEISENVPVDSS--VFKVIAIDRDVGINS- 712

Query: 187  IRYAIIGGNTQMQFSI----DSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGGSPSRSNTT 241
              Y+II GN   +F I    DS    V + K +D+E   S + L I   D      + TT
Sbjct: 713  --YSIISGNVGEKFRIETDPDSGYAIVKVAKKIDFELNESKFVLTIEVDDS---KNTATT 767

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN-AELTYTMTDKD 300
            +L I + D ND  P F    +     E+     +I  V A D D+    +E+ + +    
Sbjct: 768  ELDIRVMDANDEVPSFSQPRYLAEHPEDFAKWTTIGTVAATDRDKSEKFSEIEFEVVRVP 827

Query: 301  YTGNVDLPITIDPRSGWVYTSGQLDRE-------TQAKYQLLVTATD-----GGDPPRSA 348
               +     T+   +G V     LDRE        +  Y   VTATD      G+   +A
Sbjct: 828  EFPDSSF-FTVGSANGSVMAIKDLDREPYEDPDQIRENYIFTVTATDNVRGQSGERRNTA 886

Query: 349  TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR----LHYEIT 404
            T T              F+PG Y + + E+ P G     +   D D+D+      H  I 
Sbjct: 887  TVTFTVSITDVNDNAPEFLPG-YTLLVPENTPAGYEAGVVEIIDRDDDSNGPPFTHRVID 945

Query: 405  GGNTRGRFSITSQNG-RGLITVAQPLDFKQERR--YVLTVSATDSGGRSDTAMVQINITD 461
                   F ++S  G    + V    +F +E    Y + V  +D  G S T  + + I D
Sbjct: 946  DDGILSFFDVSSPIGVEDQLRVVSLEEFDREATPFYYIPVVLSDKHGVSATQTLTVTIGD 1005

Query: 462  ANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521
             N+  P           ++     + +  V A D D+     I+Y++++ I   +V    
Sbjct: 1006 VNDNPPSPATKTILVYSYKGQIPRSAIGEVYAADEDIVKGDDISYTVTTPIPQFSVDKDT 1065

Query: 522  QQFVINPQTGAIT 534
             Q +I   T A T
Sbjct: 1066 GQIIIEENTKAGT 1078



 Score = 92.3 bits (219), Expect = 2e-16
 Identities = 169/636 (26%), Positives = 246/636 (38%), Gaps = 79/636 (12%)

Query: 251 NDNAPRFYTSLFQESVSENVPIG---YSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
           N    +F    ++ SV EN P G   Y    + A    + V   L  T  +K    N D 
Sbjct: 112 NSEHLKFTQDRYEGSVLENSPAGTVVYGFESISACSECDLVEYSLLGTGEEKFNLENKDG 171

Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
            +TI        T+  LDRE++A Y L + A        + T                F 
Sbjct: 172 IVTIQ-------TNEVLDRESRASYNLTLVAASAS--LETETTDLLITVEDVNDNAPEFD 222

Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNR---LHYEITGGNTRGRFSITSQNGRGLIT 424
           P   EV + E  P    V  + A D D       ++Y  T   T   FS+    G G+I 
Sbjct: 223 PETCEVTVPEISPADAIVAYVHAVDPDAGKNGKVMYYTDTNDMT---FSVHPDTG-GVI- 277

Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAM----VQINITDANNY---------APVF-- 469
           +  PL   Q + Y LTV A D G  S  A     V I +T  +            PV   
Sbjct: 278 IGGPL---QAKEYTLTVFARDRGKPSLEASTPGRVIITVTPVDQSLKFSSILGPGPVILQ 334

Query: 470 ---ENAP-YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA-VAHHDQQF 524
              E  P    S+ EDAP G+ V  + A  +D   ++Q  + +++ ++    V ++    
Sbjct: 335 DDDEELPEIKVSLMEDAPKGSVVTTIKAPSNDK--SSQYRFLMNNPMNPRFHVQYYTGDI 392

Query: 525 VINPQ-------TGAITTNKLLD-----RETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572
           V+  +       T  I      D     RE      + +T     +PS +D       VV
Sbjct: 393 VLTGRLDIDAHPTEEINVGITKDFNDPLREAPKEQKVIITI----IPSETDKPAPPNQVV 448

Query: 573 DVN---DNEPVFKQQLYTANIME-DALVGTSVSQVGATDADVGLNG---RIHYELDPKDR 625
                  ++P F Q  Y   + E D L     + V      V  NG    I Y +   + 
Sbjct: 449 KPRIRRASKPSFDQPSYEGTVEEVDGLASPVPAFVPREILTVRANGDPSNIQYRIQQAEF 508

Query: 626 EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685
            E  F I   SG+I + K LDRE      ++   +       +++V V IKI+D+ND+ P
Sbjct: 509 RE-DFAIGLTSGIISSRKHLDRED-NKGQVREFTVTASNSAGTTSVEVLIKIKDVNDNAP 566

Query: 686 VFESDCLTFYISENSPIGTTIGEIRAH---DPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
            F          EN   G T+  I+A    DP+EG NA+V YSI     ++         
Sbjct: 567 QFPYPPYIGSFPENGAPGVTVMTIQAEDLDDPNEGGNALVRYSILRNAQNSVGQAIFAID 626

Query: 743 SDKAELVTMV-DLDYESPRKKYELVIRAASPPL-WNDVRVEILVTDVNDNAPVMKDFQII 800
           S+ A + T V +LD E     Y++V++A         V   I V+D NDN P     +  
Sbjct: 627 SESAVITTQVGNLDREE-IPSYDIVVKAVDGGAHTGTVTATIYVSDENDNPPEFPQAK-S 684

Query: 801 FNNYKDCFPV-GPFGRVPAYDADVTDKLQYRILSGN 835
           F    +  PV     +V A D DV     Y I+SGN
Sbjct: 685 FVEISENVPVDSSVFKVIAIDRDVGIN-SYSIISGN 719



 Score = 76.2 bits (179), Expect = 1e-11
 Identities = 67/248 (27%), Positives = 110/248 (44%), Gaps = 20/248 (8%)

Query: 421 GLITVAQPL-DFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479
           G+I   + L D+      V+     D     D+  + I  +  N+    F    Y  SV 
Sbjct: 69  GIIRSMEELTDYANRMFSVVVEQFLDDDAWKDSFNIYITKSGDNSEHLKFTQDRYEGSVL 128

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT--TNK 537
           E++P GT V    +  +    +  + YSL        +   +++F +  + G +T  TN+
Sbjct: 129 ENSPAGTVVYGFESISACSECDL-VEYSL--------LGTGEEKFNLENKDGIVTIQTNE 179

Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
           +LDRE+ + Y LT+ A    + +  +TTD+ I+V DVNDN P F  +     + E +   
Sbjct: 180 VLDRESRASYNLTLVAASASLET--ETTDLLITVEDVNDNAPEFDPETCEVTVPEISPAD 237

Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
             V+ V A D D G NG++ Y  D  D    +F + P +G +     L  +    + L  
Sbjct: 238 AIVAYVHAVDPDAGKNGKVMYYTDTNDM---TFSVHPDTGGVIIGGPLQAKE---YTLTV 291

Query: 658 VAIDGGTP 665
            A D G P
Sbjct: 292 FARDRGKP 299



 Score = 46.0 bits (104), Expect = 0.015
 Identities = 50/209 (23%), Positives = 85/209 (40%), Gaps = 17/209 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD-T 69
           I V D ND++P F+ +  E +V E + +   V  + A D D GKN +V Y  +      +
Sbjct: 209 ITVEDVNDNAPEFDPETCEVTVPEISPADAIVAYVHAVDPDAGKNGKVMYYTDTNDMTFS 268

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
           ++P+             +    +  R      + SL+     R  + V   DQ+   S  
Sbjct: 269 VHPDTGGVIIGGPLQAKEYTLTVFARDRG---KPSLEASTPGRVIITVTPVDQSLKFSSI 325

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           L     I   + DD++  P+       VS+ ED       V+  IKA   D   +S  R+
Sbjct: 326 LGPGPVI---LQDDDEELPEIK-----VSLMED--APKGSVVTTIKAPSND--KSSQYRF 373

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYE 218
            ++      +F +   +GD+ L   LD +
Sbjct: 374 -LMNNPMNPRFHVQYYTGDIVLTGRLDID 401


>UniRef50_UPI00015A41E3 Cluster: UPI00015A41E3 related cluster; n=2;
           Danio rerio|Rep: UPI00015A41E3 UniRef100 entry - Danio
           rerio
          Length = 1114

 Score =  243 bits (595), Expect = 5e-62
 Identities = 230/825 (27%), Positives = 364/825 (44%), Gaps = 75/825 (9%)

Query: 59  EYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVK 118
           EY  ++V  D   P+D               F ++  +G +  +  LDRE    +   + 
Sbjct: 44  EYAFKIVATD---PDDDPLTYKIAGTNA-GFFTVEEHTGIVTIKILLDRETTQHFKCTLV 99

Query: 119 ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178
           +T  A  +  ++  T  I++N+ D NDN P F+   Y   V E+ +V    V+    ATD
Sbjct: 100 STYNAPTLFIQVRKT--IYINVEDANDNIPIFNGLPYNKEVLENTTV--GFVLFTASATD 155

Query: 179 ADVGANSAIRYAI--IGGNTQMQFSIDSLSGDVSLVKTLDY-EQVRSYRLVIRAQDGGSP 235
           +D G    + Y I  +  + +  FSI + +G V+LV  L++ E+   Y++ I A DGG  
Sbjct: 156 SDFGQAGIVSYKIDEVVPDDKDMFSIVAATGVVTLVGNLNFTEKSPFYQIRINASDGGGE 215

Query: 236 S------RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN 289
                  +S++    I ++DV D  P+F       +V EN  +G ++  V+A D D GVN
Sbjct: 216 LYGEEVVQSSSAIAFITVKDVPDIDPQFLNLPNNAAVEENTGVGTTVFTVRARDPDTGVN 275

Query: 290 AELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET----QAKYQLLVTATDGGDPP 345
            ++T+++   D T   DL   ID  +G V  + ++DRE      A   L + A++     
Sbjct: 276 DKITFSI---DKTNASDL-FRIDTNTGIVSVNAEIDREELLNISATVVLKIKASETMPNV 331

Query: 346 RSATATXXXXXXXXXXXXXXFMPGQYEVE-------------LAEDEPPGTPVVTLTAT- 391
               A+                P  YE E             + E    G  V  L    
Sbjct: 332 NGVIASTIGELQISIKDENDNSPEFYECEGEACMKKDNFEGNVNEHSSTGLAVANLNIKV 391

Query: 392 ---DADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA------QPLDFKQERRYVLTVS 442
              D  E++  +  + G + +  F ++  +G G  TV       Q +D++ ++   + + 
Sbjct: 392 KDLDGGENSTFNLHLDGPD-KDAFRVSPTSGMGESTVQVLVKDPQAVDYEIKQIMNVQII 450

Query: 443 ATDSGGR-SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501
           A D+    + TA V I++ D N+  P FE   Y   VFE    GT V  + ATD+D    
Sbjct: 451 AVDANADFTSTATVTIHLNDTNDNFPTFEKELYKEKVFEHCENGTIVATIIATDADAFDE 510

Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL 561
            +ITY L  E        H++   I      +T    LD E    Y LT+ A D G  + 
Sbjct: 511 GKITYRLMPESIRSLFGVHEKTGTIY-----VTNGDTLDWEVTKSYTLTLQAFDSG--NN 563

Query: 562 SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG--LNGRIHYE 619
           + TT VEIS++D+NDN P   + +Y A + E+        Q+ ATD D    LN  + Y 
Sbjct: 564 TGTTVVEISILDINDNAPEMNRDIYEAFVQENE---DFKIQIQATDRDEPKTLNSEVQYR 620

Query: 620 LDPKDREEGSFVIDPASGVIRTNKALDRESV-----ATHDLKAVAIDGGTPPQSSTVIVH 674
           +  +     +F I   SG++     LDRE++         L  +A D GTP +SS+  V+
Sbjct: 621 ISEESTFSSNFTIGLESGLLTNKGDLDREAIDISQNGVIQLIVIASDLGTPSRSSSAKVN 680

Query: 675 IKIEDINDSPPVF-ESDCLTFYISENSPIGTTIGEIRAHDPDEGP-NAVVHYSIKGGDDS 732
           I + D ND+ P + +S    F + E S  G  +G + AHD D+   N  + +SI  G   
Sbjct: 681 ISVGDANDNAPRYLDSSPYEFRVKE-SVKGIYVGPVHAHDADQTDFNNRIFFSITDGSFG 739

Query: 733 NSFSLETRQGSDKAELVTM---VDLDYESPRKKYELVIRAASPPLWNDV-RVEILVTDVN 788
           +               +T+   V+LDYES RK+Y L ++A+     +DV  V I+V DVN
Sbjct: 740 SFIIYSEAFSKGYRGNITVDPSVELDYESNRKEYTLKVQASDLGQKSDVAEVHIIVEDVN 799

Query: 789 DNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILS 833
           D  P      I+  +     PV P   +   D D    L Y ++S
Sbjct: 800 DTPPEFPSGMILKVDENTTLPV-PVDTIKGKDVDTNHSLIYELVS 843



 Score =  206 bits (503), Expect = 7e-51
 Identities = 206/755 (27%), Positives = 330/755 (43%), Gaps = 89/755 (11%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           INV D ND+ P+F    Y   V E  + G  + T  ATD D G+   V Y I+ V     
Sbjct: 117 INVEDANDNIPIFNGLPYNKEVLENTTVGFVLFTASATDSDFGQAGIVSYKIDEVV---- 172

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLD-REKVARYTVLVKATDQASPVSDR 129
            P+D            +D+F I   +G +    +L+  EK   Y + + A+D    +   
Sbjct: 173 -PDD------------KDMFSIVAATGVVTLVGNLNFTEKSPFYQIRINASDGGGELYGE 219

Query: 130 ---LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
               SS+A   + + D  D  PQF       +V+E+  V     +  ++A D D G N  
Sbjct: 220 EVVQSSSAIAFITVKDVPDIDPQFLNLPNNAAVEENTGV--GTTVFTVRARDPDTGVNDK 277

Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT----- 241
           I ++I   N    F ID+ +G VS+   +D E++ +    +  +   S +  N       
Sbjct: 278 ITFSIDKTNASDLFRIDTNTGIVSVNAEIDREELLNISATVVLKIKASETMPNVNGVIAS 337

Query: 242 ---QLLINIRDVNDNAPRFYT---------SLFQESVSENVPIGYSI--VRVQAYDADEG 287
              +L I+I+D NDN+P FY            F+ +V+E+   G ++  + ++  D D G
Sbjct: 338 TIGELQISIKDENDNSPEFYECEGEACMKKDNFEGNVNEHSSTGLAVANLNIKVKDLDGG 397

Query: 288 VNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL--------DRETQAKYQLLVTAT 339
            N+     +   D          + P SG   ++ Q+        D E +    + + A 
Sbjct: 398 ENSTFNLHLDGPDKDA-----FRVSPTSGMGESTVQVLVKDPQAVDYEIKQIMNVQIIAV 452

Query: 340 DGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDN 397
           D  +   ++TAT              F    Y+ ++ E    GT V T+ ATDAD  ++ 
Sbjct: 453 DA-NADFTSTATVTIHLNDTNDNFPTFEKELYKEKVFEHCENGTIVATIIATDADAFDEG 511

Query: 398 RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQI 457
           ++ Y +   + R  F +  + G   +T    LD++  + Y LT+ A DSG  + T +V+I
Sbjct: 512 KITYRLMPESIRSLFGVHEKTGTIYVTNGDTLDWEVTKSYTLTLQAFDSGNNTGTTVVEI 571

Query: 458 NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD--VGINAQITYSLSSEISNE 515
           +I D N+ AP      Y A V E+       + + ATD D    +N+++ Y +S E    
Sbjct: 572 SILDINDNAPEMNRDIYEAFVQENEDF---KIQIQATDRDEPKTLNSEVQYRISEE---- 624

Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRE----TMSGYL-LTVTARDGGVPSLSDTTDVEIS 570
             +     F I  ++G +T    LDRE    + +G + L V A D G PS S +  V IS
Sbjct: 625 --STFSSNFTIGLESGLLTNKGDLDREAIDISQNGVIQLIVIASDLGTPSRSSSAKVNIS 682

Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGS 629
           V D NDN P +         +++++ G  V  V A DAD    N RI + +   D   GS
Sbjct: 683 VGDANDNAPRYLDSSPYEFRVKESVKGIYVGPVHAHDADQTDFNNRIFFSI--TDGSFGS 740

Query: 630 FVI--DPASGVIRTNKALD-------RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680
           F+I  +  S   R N  +D         +   + LK  A D G   +S    VHI +ED+
Sbjct: 741 FIIYSEAFSKGYRGNITVDPSVELDYESNRKEYTLKVQASDLG--QKSDVAEVHIIVEDV 798

Query: 681 NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
           ND+PP F S  +   + EN+ +   +  I+  D D
Sbjct: 799 NDTPPEFPSG-MILKVDENTTLPVPVDTIKGKDVD 832



 Score =  181 bits (441), Expect = 2e-43
 Identities = 187/648 (28%), Positives = 292/648 (45%), Gaps = 75/648 (11%)

Query: 10  QINVLDCNDHSPVF---------EMQQYEASVREGASSGTTV--LTLKATDQDIGKNAEV 58
           QI++ D ND+SP F         +   +E +V E +S+G  V  L +K  D D G+N+  
Sbjct: 343 QISIKDENDNSPEFYECEGEACMKKDNFEGNVNEHSSTGLAVANLNIKVKDLDGGENSTF 402

Query: 59  EYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVK 118
              ++    D                 VQ + +            ++D E      V + 
Sbjct: 403 NLHLDGPDKDAFR---VSPTSGMGESTVQVLVK---------DPQAVDYEIKQIMNVQII 450

Query: 119 ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178
           A D  +      +STAT+ +++ D NDN+P F ++ Y   V E     +  ++A I ATD
Sbjct: 451 AVDANAD----FTSTATVTIHLNDTNDNFPTFEKELYKEKVFEHCE--NGTIVATIIATD 504

Query: 179 ADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVK--TLDYEQVRSYRLVIRAQDGGSPS 236
           AD      I Y ++  + +  F +   +G + +    TLD+E  +SY L ++A D G+  
Sbjct: 505 ADAFDEGKITYRLMPESIRSLFGVHEKTGTIYVTNGDTLDWEVTKSYTLTLQAFDSGN-- 562

Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG--VNAELTY 294
            + TT + I+I D+NDNAP     +++  V EN       +++QA D DE   +N+E+ Y
Sbjct: 563 NTGTTVVEISILDINDNAPEMNRDIYEAFVQENEDFK---IQIQATDRDEPKTLNSEVQY 619

Query: 295 TMTDKD-YTGNVDLPITIDPRSGWVYTSGQLDRET-----QAKYQLLVTATDGGDPPRSA 348
            ++++  ++ N     TI   SG +   G LDRE          QL+V A+D G P RS+
Sbjct: 620 RISEESTFSSN----FTIGLESGLLTNKGDLDREAIDISQNGVIQLIVIASDLGTPSRSS 675

Query: 349 TATXXXXXXXXXXXXXXFMPGQ-YEVELAEDEPPGTPVVTLTATDADE---DNRLHYEIT 404
           +A               ++    YE  + E    G  V  + A DAD+   +NR+ + IT
Sbjct: 676 SAKVNISVGDANDNAPRYLDSSPYEFRVKESVK-GIYVGPVHAHDADQTDFNNRIFFSIT 734

Query: 405 GGNTRGRFSITSQ----NGRGLITV--AQPLDFKQERR-YVLTVSATDSGGRSDTAMVQI 457
            G+  G F I S+      RG ITV  +  LD++  R+ Y L V A+D G +SD A V I
Sbjct: 735 DGSF-GSFIIYSEAFSKGYRGNITVDPSVELDYESNRKEYTLKVQASDLGQKSDVAEVHI 793

Query: 458 NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS--NE 515
            + D N+  P F +      V E+  +   V  +   D D   N  + Y L S     N 
Sbjct: 794 IVEDVNDTPPEFPSG-MILKVDENTTLPVPVDTIKGKDVDT--NHSLIYELVSTKCQCNG 850

Query: 516 AVAHHDQQFVINPQTGAITTNK--LLDRETMSGYLLTVTARD----GGVPSLSDTTDVEI 569
            +    +++ I    G I  N   ++D E      LT    D     G  S   +  V I
Sbjct: 851 TIGPCPEEWFIVESNGDIIANTEYVIDYEKCDVVFLTARVVDIYTEVGSNSSEGSGVVTI 910

Query: 570 SVVDVNDNEP--VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615
           ++VD+NDN P  VF Q  Y   ++E    GTSV++  ATD D   N +
Sbjct: 911 NIVDINDNAPEFVFLQDFYVV-VIEKVDTGTSVARAYATDRDTADNNK 957



 Score =  155 bits (376), Expect = 2e-35
 Identities = 193/770 (25%), Positives = 323/770 (41%), Gaps = 71/770 (9%)

Query: 154 TYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVK 213
           T  V + ED+ + +     KI ATD D   +  + Y I G N    F+++  +G V++  
Sbjct: 31  TSVVILREDLRIGEYAF--KIVATDPD---DDPLTYKIAGTNAGF-FTVEEHTGIVTIKI 84

Query: 214 TLDYEQVRSYRL-VIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI 272
            LD E  + ++  ++   +  +        + IN+ D NDN P F    + + V EN  +
Sbjct: 85  LLDRETTQHFKCTLVSTYNAPTLFIQVRKTIYINVEDANDNIPIFNGLPYNKEVLENTTV 144

Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD-RETQAK 331
           G+ +    A D+D G    ++Y + D+    + D+  +I   +G V   G L+  E    
Sbjct: 145 GFVLFTASATDSDFGQAGIVSYKI-DEVVPDDKDM-FSIVAATGVVTLVGNLNFTEKSPF 202

Query: 332 YQLLVTATDGG------DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
           YQ+ + A+DGG      +  +S++A               F+       + E+   GT V
Sbjct: 203 YQIRINASDGGGELYGEEVVQSSSAIAFITVKDVPDIDPQFLNLPNNAAVEENTGVGTTV 262

Query: 386 VTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ----ERRYVL 439
            T+ A D D   ++++ + I   N    F I +    G+++V   +D ++        VL
Sbjct: 263 FTVRARDPDTGVNDKITFSIDKTNASDLFRIDTNT--GIVSVNAEIDREELLNISATVVL 320

Query: 440 TVSATDS----GG--RSDTAMVQINITDANNYAPVF---------ENAPYTASVFEDAPI 484
            + A+++     G   S    +QI+I D N+ +P F         +   +  +V E +  
Sbjct: 321 KIKASETMPNVNGVIASTIGELQISIKDENDNSPEFYECEGEACMKKDNFEGNVNEHSST 380

Query: 485 GTTV--LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
           G  V  L +   D D G N+     L     +            +     +   + +D E
Sbjct: 381 GLAVANLNIKVKDLDGGENSTFNLHLDGPDKDAFRVSPTSGMGESTVQVLVKDPQAVDYE 440

Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
                 + + A D      + T  V I + D NDN P F+++LY   + E    GT V+ 
Sbjct: 441 IKQIMNVQIIAVDANA-DFTSTATVTIHLNDTNDNFPTFEKELYKEKVFEHCENGTIVAT 499

Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN-KALDRESVATHDLKAVAID 661
           + ATDAD    G+I Y L P+       V +    +  TN   LD E   ++ L   A D
Sbjct: 500 IIATDADAFDEGKITYRLMPESIRSLFGVHEKTGTIYVTNGDTLDWEVTKSYTLTLQAFD 559

Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP--N 719
            G    + T +V I I DIND+ P    D    ++ EN        +I+A D DE    N
Sbjct: 560 SGN--NTGTTVVEISILDINDNAPEMNRDIYEAFVQENEDFKI---QIQATDRDEPKTLN 614

Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE----SPRKKYELVIRAA---SP 772
           + V Y I    + ++FS     G +   L    DLD E    S     +L++ A+   +P
Sbjct: 615 SEVQYRI---SEESTFSSNFTIGLESGLLTNKGDLDREAIDISQNGVIQLIVIASDLGTP 671

Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD---KLQY 829
              +  +V I V D NDNAP   D        K+       G V A+DAD TD   ++ +
Sbjct: 672 SRSSSAKVNISVGDANDNAPRYLDSSPYEFRVKESVKGIYVGPVHAHDADQTDFNNRIFF 731

Query: 830 RILSGNNANLILLNET-----TGSMTLSPQLNTNVP---KLATMEVSVTD 871
            I  G+  + I+ +E       G++T+ P +  +     K  T++V  +D
Sbjct: 732 SITDGSFGSFIIYSEAFSKGYRGNITVDPSVELDYESNRKEYTLKVQASD 781



 Score =  155 bits (375), Expect = 2e-35
 Identities = 207/765 (27%), Positives = 321/765 (41%), Gaps = 96/765 (12%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V D  D  P F      A+V E    GTTV T++A D D G N ++ ++I+   A   
Sbjct: 231 ITVKDVPDIDPQFLNLPNNAAVEENTGVGTTVFTVRARDPDTGVNDKITFSIDKTNAS-- 288

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKV----ARYTVLVKATDQASPV 126
                            D+FRID  +G +   A +DRE++    A   + +KA++    V
Sbjct: 289 -----------------DLFRIDTNTGIVSVNAEIDREELLNISATVVLKIKASETMPNV 331

Query: 127 SDRLSST-ATIHVNIIDDNDNYPQFSE---------KTYTVSVDEDISVTDNPVIAKIKA 176
           +  ++ST   + ++I D+NDN P+F E           +  +V+E  S         IK 
Sbjct: 332 NGVIASTIGELQISIKDENDNSPEFYECEGEACMKKDNFEGNVNEHSSTGLAVANLNIKV 391

Query: 177 TDADVGANSAIRYAIIGGNTQMQFSIDSLSG-DVSLVKTL-------DYEQVRSYRLVIR 228
            D D G NS     + G +    F +   SG   S V+ L       DYE  +   + I 
Sbjct: 392 KDLDGGENSTFNLHLDGPDKDA-FRVSPTSGMGESTVQVLVKDPQAVDYEIKQIMNVQII 450

Query: 229 AQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV 288
           A D  +   S  T + I++ D NDN P F   L++E V E+   G  +  + A DAD   
Sbjct: 451 AVDANADFTSTAT-VTIHLNDTNDNFPTFEKELYKEKVFEHCENGTIVATIIATDADAFD 509

Query: 289 NAELTYTMTDKDYTGNVDLPITIDPRSGWVY-TSGQ-LDRETQAKYQLLVTATDGGDPPR 346
             ++TY +  +    ++     +  ++G +Y T+G  LD E    Y L + A D G+   
Sbjct: 510 EGKITYRLMPE----SIRSLFGVHEKTGTIYVTNGDTLDWEVTKSYTLTLQAFDSGN--N 563

Query: 347 SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH----YE 402
           + T                     YE  + E+E      + + ATD DE   L+    Y 
Sbjct: 564 TGTTVVEISILDINDNAPEMNRDIYEAFVQENEDFK---IQIQATDRDEPKTLNSEVQYR 620

Query: 403 ITGGNT-RGRFSITSQNG----RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMV 455
           I+  +T    F+I  ++G    +G +   + +D  Q     L V A+D G   RS +A V
Sbjct: 621 ISEESTFSSNFTIGLESGLLTNKGDLD-REAIDISQNGVIQLIVIASDLGTPSRSSSAKV 679

Query: 456 QINITDANNYAPVF-ENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEIS 513
            I++ DAN+ AP + +++PY   V E    G  V  V A D+D    N +I +S++    
Sbjct: 680 NISVGDANDNAPRYLDSSPYEFRVKESVK-GIYVGPVHAHDADQTDFNNRIFFSITDGSF 738

Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSG---YLLTVTARDGGVPSLSDTTDVEIS 570
              + + +         G IT +  ++ +  S    Y L V A D G    SD  +V I 
Sbjct: 739 GSFIIYSEA--FSKGYRGNITVDPSVELDYESNRKEYTLKVQASDLG--QKSDVAEVHII 794

Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGS 629
           V DVND  P F   +    + E+  +   V  +   D D   N  + YEL   K +  G+
Sbjct: 795 VEDVNDTPPEFPSGMIL-KVDENTTLPVPVDTIKGKDVDT--NHSLIYELVSTKCQCNGT 851

Query: 630 --------FVIDPASGVI-RTNKALDRESVATHDLKAVAID----GGTPPQSSTVIVHIK 676
                   F+++    +I  T   +D E      L A  +D     G+     + +V I 
Sbjct: 852 IGPCPEEWFIVESNGDIIANTEYVIDYEKCDVVFLTARVVDIYTEVGSNSSEGSGVVTIN 911

Query: 677 IEDINDSPP--VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
           I DIND+ P  VF  D     I E    GT++    A D D   N
Sbjct: 912 IVDINDNAPEFVFLQDFYVVVI-EKVDTGTSVARAYATDRDTADN 955



 Score =  147 bits (355), Expect = 6e-33
 Identities = 151/553 (27%), Positives = 245/553 (44%), Gaps = 54/553 (9%)

Query: 373 VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432
           V L ED   G     + ATD D+D  L Y+I G N  G F++    G  ++T+   LD +
Sbjct: 34  VILREDLRIGEYAFKIVATDPDDDP-LTYKIAGTNA-GFFTVEEHTG--IVTIKILLDRE 89

Query: 433 QERRYVLTVSATDSGGRSDTAM---VQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
             + +  T+ +T +       +   + IN+ DAN+  P+F   PY   V E+  +G  + 
Sbjct: 90  TTQHFKCTLVSTYNAPTLFIQVRKTIYINVEDANDNIPIFNGLPYNKEVLENTTVGFVLF 149

Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT-TNKLLDRETMSGYL 548
             SATDSD G    ++Y +     +E V      F I   TG +T    L   E    Y 
Sbjct: 150 TASATDSDFGQAGIVSYKI-----DEVVPDDKDMFSIVAATGVVTLVGNLNFTEKSPFYQ 204

Query: 549 LTVTARDGGVPSL------SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
           + + A DGG          S +    I+V DV D +P F      A + E+  VGT+V  
Sbjct: 205 IRINASDGGGELYGEEVVQSSSAIAFITVKDVPDIDPQFLNLPNNAAVEENTGVGTTVFT 264

Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV----ATHDLKAV 658
           V A D D G+N +I + +D K      F ID  +G++  N  +DRE +    AT  LK  
Sbjct: 265 VRARDPDTGVNDKITFSID-KTNASDLFRIDTNTGIVSVNAEIDREELLNISATVVLKIK 323

Query: 659 AIDGGTPPQSSTVI------VHIKIEDINDSPPVF---------ESDCLTFYISENSPIG 703
           A +  T P  + VI      + I I+D ND+ P F         + D     ++E+S  G
Sbjct: 324 ASE--TMPNVNGVIASTIGELQISIKDENDNSPEFYECEGEACMKKDNFEGNVNEHSSTG 381

Query: 704 TTIG--EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD----LDYE 757
             +    I+  D D G N+  +  +  G D ++F +    G  ++ +  +V     +DYE
Sbjct: 382 LAVANLNIKVKDLDGGENSTFNLHL-DGPDKDAFRVSPTSGMGESTVQVLVKDPQAVDYE 440

Query: 758 SPR-KKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRV 816
             +    +++   A+    +   V I + D NDN P  +        ++ C        +
Sbjct: 441 IKQIMNVQIIAVDANADFTSTATVTIHLNDTNDNFPTFEKELYKEKVFEHCENGTIVATI 500

Query: 817 PAYDADVTD--KLQYRILSGNNANLILLNETTGS--MTLSPQLNTNVPKLATMEVSVTD- 871
            A DAD  D  K+ YR++  +  +L  ++E TG+  +T    L+  V K  T+ +   D 
Sbjct: 501 IATDADAFDEGKITYRLMPESIRSLFGVHEKTGTIYVTNGDTLDWEVTKSYTLTLQAFDS 560

Query: 872 GVNEIKAMMQLSV 884
           G N    ++++S+
Sbjct: 561 GNNTGTTVVEISI 573



 Score = 56.8 bits (131), Expect = 8e-06
 Identities = 61/205 (29%), Positives = 91/205 (44%), Gaps = 30/205 (14%)

Query: 113 YTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV-I 171
           YT+ V+A+D         S  A +H+ + D ND  P+F      + VDE+ ++   PV +
Sbjct: 773 YTLKVQASDLGQK-----SDVAEVHIIVEDVNDTPPEFPSGMI-LKVDENTTL---PVPV 823

Query: 172 AKIKATDADVGANSAIRYAIIGGNTQMQ----------FSIDSLSGDV--SLVKTLDYEQ 219
             IK  D D   N ++ Y ++    Q            F ++S +GD+  +    +DYE+
Sbjct: 824 DTIKGKDVDT--NHSLIYELVSTKCQCNGTIGPCPEEWFIVES-NGDIIANTEYVIDYEK 880

Query: 220 VRSYRLVIRAQD----GGSPSRSNTTQLLINIRDVNDNAPRF-YTSLFQESVSENVPIGY 274
                L  R  D     GS S   +  + INI D+NDNAP F +   F   V E V  G 
Sbjct: 881 CDVVFLTARVVDIYTEVGSNSSEGSGVVTINIVDINDNAPEFVFLQDFYVVVIEKVDTGT 940

Query: 275 SIVRVQAYDADEGVNAELTYTMTDK 299
           S+ R  A D D   N + T    +K
Sbjct: 941 SVARAYATDRDTADNNKKTKFQVNK 965



 Score = 36.7 bits (81), Expect = 9.2
 Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 2/58 (3%)

Query: 11  INVLDCNDHSPVFE-MQQYEASVREGASSGTTVLTLKATDQDIG-KNAEVEYTIELVT 66
           IN++D ND++P F  +Q +   V E   +GT+V    ATD+D    N + ++ +  +T
Sbjct: 910 INIVDINDNAPEFVFLQDFYVVVIEKVDTGTSVARAYATDRDTADNNKKTKFQVNKIT 967


>UniRef50_A7SHT2 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 470

 Score =  242 bits (593), Expect = 8e-62
 Identities = 169/491 (34%), Positives = 250/491 (50%), Gaps = 31/491 (6%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F ++  +G +    SLDRE  A Y+V V A+D       +  +   I V+I D ND YP 
Sbjct: 1   FAVNKTTGDIKVTRSLDRESNASYSVTVMASD------GKFQAFLEIDVHIQDINDQYPV 54

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209
           FS + Y+V++ E+ S    PV+ ++ A D D G+NS + Y+I+ GN+   FSID  +G +
Sbjct: 55  FSPQNYSVAISEE-SWVRLPVL-QVTAVDMDSGSNSQVTYSIVDGNS--SFSIDPNTGQI 110

Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPS--RSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
            + +TLD+E  RS+ L ++A+D G P+    +   + INI D NDN P F    +  S++
Sbjct: 111 IVHRTLDFEVTRSFILRVQARDNGKPALVSRDYAYVTINITDENDNNPVFDKRSYNFSIT 170

Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
           E+V  G     V+A DAD G NA+L+Y++ D+D    V     +D  +G +   G +DRE
Sbjct: 171 EDVAKGTVFGFVRANDADSGKNAKLSYSIPDED----VRKTFAVDEITGNLSVVGDIDRE 226

Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387
               Y  +V  TD G  PR   A               F P  Y V ++E    GT +V 
Sbjct: 227 RTGIYSFVVVVTDHGSSPRVGFAVVSVQVKDVNDNQPIFRPQNYTVRISEGTSVGTKIVW 286

Query: 388 LTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445
           + A D D   +  + Y I  GN    F I      G I +   LD +   +Y L + ATD
Sbjct: 287 VHAHDEDIGPNALITYHIDSGNKESIFDIED----GTIVLNGTLDREVMDQYTLGILATD 342

Query: 446 SGG----RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501
           +G       D A+V I I D N+  P F  + Y+ ++ ED  IGT VL V A+D D+G N
Sbjct: 343 NGEPPQLSRDPAIVVITIEDINDNYPEFNASVYSVNISEDTSIGTQVLSVYASDKDLGSN 402

Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG-YLLTVTARDGGVPS 560
           A + Y + +  +++      + F +N  TGAI+T   LD E+ +  +   V ARD G P+
Sbjct: 403 AHVQYFIIASANDDI----KRVFDVNKTTGAISTTSNLDFESANNRFQFQVEARDNGKPA 458

Query: 561 LSDTTDVEISV 571
           L   T VEI V
Sbjct: 459 LYSQTTVEIMV 469



 Score =  205 bits (501), Expect = 1e-50
 Identities = 146/489 (29%), Positives = 227/489 (46%), Gaps = 31/489 (6%)

Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259
           F+++  +GD+ + ++LD E   SY + + A DG   +     ++ ++I+D+ND  P F  
Sbjct: 1   FAVNKTTGDIKVTRSLDRESNASYSVTVMASDGKFQA---FLEIDVHIQDINDQYPVFSP 57

Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319
             +  ++SE   +   +++V A D D G N+++TY++ D    GN     +IDP +G + 
Sbjct: 58  QNYSVAISEESWVRLPVLQVTAVDMDSGSNSQVTYSIVD----GNSS--FSIDPNTGQII 111

Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRSAT--ATXXXXXXXXXXXXXXFMPGQYEVELAE 377
               LD E    + L V A D G P   +   A               F    Y   + E
Sbjct: 112 VHRTLDFEVTRSFILRVQARDNGKPALVSRDYAYVTINITDENDNNPVFDKRSYNFSITE 171

Query: 378 DEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435
           D   GT    + A DAD  ++ +L Y I   + R  F++    G   ++V   +D ++  
Sbjct: 172 DVAKGTVFGFVRANDADSGKNAKLSYSIPDEDVRKTFAVDEITGN--LSVVGDIDRERTG 229

Query: 436 RYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
            Y   V  TD G   R   A+V + + D N+  P+F    YT  + E   +GT ++ V A
Sbjct: 230 IYSFVVVVTDHGSSPRVGFAVVSVQVKDVNDNQPIFRPQNYTVRISEGTSVGTKIVWVHA 289

Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553
            D D+G NA ITY + S          +++ + + + G I  N  LDRE M  Y L + A
Sbjct: 290 HDEDIGPNALITYHIDS---------GNKESIFDIEDGTIVLNGTLDREVMDQYTLGILA 340

Query: 554 RDGG-VPSLS-DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG 611
            D G  P LS D   V I++ D+NDN P F   +Y+ NI ED  +GT V  V A+D D+G
Sbjct: 341 TDNGEPPQLSRDPAIVVITIEDINDNYPEFNASVYSVNISEDTSIGTQVLSVYASDKDLG 400

Query: 612 LNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATH-DLKAVAIDGGTPPQS 668
            N  + Y +     D  +  F ++  +G I T   LD ES       +  A D G P   
Sbjct: 401 SNAHVQYFIIASANDDIKRVFDVNKTTGAISTTSNLDFESANNRFQFQVEARDNGKPALY 460

Query: 669 STVIVHIKI 677
           S   V I +
Sbjct: 461 SQTTVEIMV 469



 Score =  200 bits (489), Expect = 3e-49
 Identities = 140/448 (31%), Positives = 220/448 (49%), Gaps = 30/448 (6%)

Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
           G I V + LD +    Y +TV A+D G       + ++I D N+  PVF    Y+ ++ E
Sbjct: 8   GDIKVTRSLDRESNASYSVTVMASD-GKFQAFLEIDVHIQDINDQYPVFSPQNYSVAISE 66

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           ++ +   VL V+A D D G N+Q+TYS         +   +  F I+P TG I  ++ LD
Sbjct: 67  ESWVRLPVLQVTAVDMDSGSNSQVTYS---------IVDGNSSFSIDPNTGQIIVHRTLD 117

Query: 541 RETMSGYLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            E    ++L V ARD G P+L   D   V I++ D NDN PVF ++ Y  +I ED   GT
Sbjct: 118 FEVTRSFILRVQARDNGKPALVSRDYAYVTINITDENDNNPVFDKRSYNFSITEDVAKGT 177

Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
               V A DAD G N ++ Y +  +D  + +F +D  +G +     +DRE    +    V
Sbjct: 178 VFGFVRANDADSGKNAKLSYSIPDEDVRK-TFAVDEITGNLSVVGDIDRERTGIYSFVVV 236

Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
             D G+ P+    +V ++++D+ND+ P+F     T  ISE + +GT I  + AHD D GP
Sbjct: 237 VTDHGSSPRVGFAVVSVQVKDVNDNQPIFRPQNYTVRISEGTSVGTKIVWVHAHDEDIGP 296

Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS----PPL 774
           NA++ Y I  G+  + F +E         +V    LD E    +Y L I A      P L
Sbjct: 297 NALITYHIDSGNKESIFDIE------DGTIVLNGTLDRE-VMDQYTLGILATDNGEPPQL 349

Query: 775 WNDVRVEIL-VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRI 831
             D  + ++ + D+NDN P         N  +D         V A D D+     +QY I
Sbjct: 350 SRDPAIVVITIEDINDNYPEFNASVYSVNISEDTSIGTQVLSVYASDKDLGSNAHVQYFI 409

Query: 832 LSGNNANL---ILLNETTGSMTLSPQLN 856
           ++  N ++     +N+TTG+++ +  L+
Sbjct: 410 IASANDDIKRVFDVNKTTGAISTTSNLD 437



 Score =  185 bits (450), Expect = 2e-44
 Identities = 130/443 (29%), Positives = 205/443 (46%), Gaps = 36/443 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           +++ D ND  PVF  Q Y  ++ E +     VL + A D D G N++V Y+I  V  ++ 
Sbjct: 43  VHIQDINDQYPVFSPQNYSVAISEESWVRLPVLQVTAVDMDSGSNSQVTYSI--VDGNS- 99

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                              F ID  +G ++   +LD E    + + V+A D   P     
Sbjct: 100 ------------------SFSIDPNTGQIIVHRTLDFEVTRSFILRVQARDNGKPALVS- 140

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
              A + +NI D+NDN P F +++Y  S+ ED  V    V   ++A DAD G N+ + Y+
Sbjct: 141 RDYAYVTINITDENDNNPVFDKRSYNFSITED--VAKGTVFGFVRANDADSGKNAKLSYS 198

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
           I   + +  F++D ++G++S+V  +D E+   Y  V+   D GS  R     + + ++DV
Sbjct: 199 IPDEDVRKTFAVDEITGNLSVVGDIDRERTGIYSFVVVVTDHGSSPRVGFAVVSVQVKDV 258

Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
           NDN P F    +   +SE   +G  IV V A+D D G NA +TY +     +GN +    
Sbjct: 259 NDNQPIFRPQNYTVRISEGTSVGTKIVWVHAHDEDIGPNALITYHID----SGNKE--SI 312

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA--TATXXXXXXXXXXXXXXFMP 368
            D   G +  +G LDRE   +Y L + ATD G+PP+ +   A               F  
Sbjct: 313 FDIEDGTIVLNGTLDREVMDQYTLGILATDNGEPPQLSRDPAIVVITIEDINDNYPEFNA 372

Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYE---ITGGNTRGRFSITSQNGRGLITV 425
             Y V ++ED   GT V+++ A+D D  +  H +   I   N   +         G I+ 
Sbjct: 373 SVYSVNISEDTSIGTQVLSVYASDKDLGSNAHVQYFIIASANDDIKRVFDVNKTTGAIST 432

Query: 426 AQPLDFKQ-ERRYVLTVSATDSG 447
              LDF+    R+   V A D+G
Sbjct: 433 TSNLDFESANNRFQFQVEARDNG 455



 Score =  158 bits (383), Expect = 2e-36
 Identities = 110/337 (32%), Positives = 167/337 (49%), Gaps = 30/337 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           IN+ D ND++PVF+ + Y  S+ E  + GT    ++A D D GKNA++ Y+I        
Sbjct: 148 INITDENDNNPVFDKRSYNFSITEDVAKGTVFGFVRANDADSGKNAKLSYSI-------- 199

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            P++           V+  F +D  +G L     +DRE+   Y+ +V  TD  S  S R+
Sbjct: 200 -PDE----------DVRKTFAVDEITGNLSVVGDIDRERTGIYSFVVVVTDHGS--SPRV 246

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
              A + V + D NDN P F  + YTV + E  SV     I  + A D D+G N+ I Y 
Sbjct: 247 -GFAVVSVQVKDVNDNQPIFRPQNYTVRISEGTSV--GTKIVWVHAHDEDIGPNALITYH 303

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR--SNTTQLLINIR 248
           I  GN +  F I+   G + L  TLD E +  Y L I A D G P +   +   ++I I 
Sbjct: 304 IDSGNKESIFDIE--DGTIVLNGTLDREVMDQYTLGILATDNGEPPQLSRDPAIVVITIE 361

Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
           D+NDN P F  S++  ++SE+  IG  ++ V A D D G NA + Y +       ++   
Sbjct: 362 DINDNYPEFNASVYSVNISEDTSIGTQVLSVYASDKDLGSNAHVQYFII-ASANDDIKRV 420

Query: 309 ITIDPRSGWVYTSGQLDRET-QAKYQLLVTATDGGDP 344
             ++  +G + T+  LD E+   ++Q  V A D G P
Sbjct: 421 FDVNKTTGAISTTSNLDFESANNRFQFQVEARDNGKP 457



 Score = 88.6 bits (210), Expect = 2e-15
 Identities = 75/249 (30%), Positives = 122/249 (48%), Gaps = 17/249 (6%)

Query: 630 FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES 689
           F ++  +G I+  ++LDRES A++ +  +A DG      + + + + I+DIND  PVF  
Sbjct: 1   FAVNKTTGDIKVTRSLDRESNASYSVTVMASDGKF---QAFLEIDVHIQDINDQYPVFSP 57

Query: 690 DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV 749
              +  ISE S +   + ++ A D D G N+ V YSI  G+  +SFS++   G    +++
Sbjct: 58  QNYSVAISEESWVRLPVLQVTAVDMDSGSNSQVTYSIVDGN--SSFSIDPNTG----QII 111

Query: 750 TMVDLDYESPRKKYELVIRA---ASPPLWND--VRVEILVTDVNDNAPVMKDFQIIFNNY 804
               LD+E  R  + L ++A     P L +     V I +TD NDN PV       F+  
Sbjct: 112 VHRTLDFEVTRS-FILRVQARDNGKPALVSRDYAYVTINITDENDNNPVFDKRSYNFSIT 170

Query: 805 KDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKL 862
           +D      FG V A DAD     KL Y I   +      ++E TG++++   ++     +
Sbjct: 171 EDVAKGTVFGFVRANDADSGKNAKLSYSIPDEDVRKTFAVDEITGNLSVVGDIDRERTGI 230

Query: 863 ATMEVSVTD 871
            +  V VTD
Sbjct: 231 YSFVVVVTD 239


>UniRef50_Q8N6Y1 Cluster: Protocadherin-20 precursor; n=28;
           Euteleostomi|Rep: Protocadherin-20 precursor - Homo
           sapiens (Human)
          Length = 924

 Score =  242 bits (593), Expect = 8e-62
 Identities = 186/669 (27%), Positives = 303/669 (45%), Gaps = 28/669 (4%)

Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195
           + + I D NDN PQF     +V V E+  V     I    A D DVG N    Y ++  +
Sbjct: 168 VKIAIRDINDNAPQFPVSQISVWVPENAPVNTRLAIEH-PAVDPDVGINGVQTYRLLDYH 226

Query: 196 TQMQFSID-SLSGD----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
                 ++ + +G+    + ++  LD E    Y  +I A+DGGSP    +  L I I D+
Sbjct: 227 GMFTLDVEENENGERTPYLIVMGALDRETQDQYVSIIIAEDGGSPPLLGSATLTIGISDI 286

Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
           NDN P F  S    +V  N  +G  I  VQA D D G NA++TY+ + K    + DL   
Sbjct: 287 NDNCPLFTDSQINVTVYGNATVGTPIAAVQAVDKDLGTNAQITYSYSQKVPQASKDL-FH 345

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX--XXXXXFMP 368
           +D  +G +    ++       ++L + A   G  P   TA                 ++ 
Sbjct: 346 LDENTGVIKLFSKIGGSVLESHKLTILANGPGCIPAVITALVSIIKVIFRPPEIVPRYIA 405

Query: 369 GQYE--VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
            + +  V L E EP  TP+   T  D +   +++  + G            N   L+   
Sbjct: 406 NEIDGVVYLKELEPVNTPIAFFTIRDPEGKYKVNCYLDGEGPFRLSPYKPYNNEYLLETT 465

Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
           +P+D++ ++ Y + V A +S G     ++++ + D N+ AP+F       ++ E+     
Sbjct: 466 KPMDYELQQFYEVAVVAWNSEGFHVKRVIKVQLLDDNDNAPIFLQPLIELTIEENNSPNA 525

Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
            +  + ATD+D     Q++Y L  +  +         F ++  TG +T +  LDRE    
Sbjct: 526 FLTKLYATDADSEERGQVSYFLGPDAPS--------YFSLDSVTGILTVSTQLDREEKEK 577

Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
           Y  TV A D G P       V ++V+D NDN P F  + ++  + E+      +  +  T
Sbjct: 578 YRYTVRAVDCGKPPRESVATVALTVLDKNDNSPRFINKDFSFFVPENFPGYGEIGVISVT 637

Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
           DAD G NG +   +     +   FVID   G++R   +LDRE  +++ L   A+DGG P 
Sbjct: 638 DADAGRNGWVALSV---VNQSDIFVIDTGKGMLRAKVSLDREQQSSYTLWVEAVDGGEPA 694

Query: 667 QSSTVIVHIKIEDINDSPP--VFESDCLTFYISENSPI-GTTIGEIRAHDPDEGPNAVVH 723
            SST  + I + DIND+PP  +F    +++ +   S + G+ + E+ A D D G NAV+ 
Sbjct: 695 LSSTAKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGSPVTEVYAVDKDTGMNAVIA 754

Query: 724 YSIKG--GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781
           YSI G  G    SF ++ + G+   E   ++  DY   R   ++       PL + V V 
Sbjct: 755 YSIIGRRGPRPESFRIDPKTGNITLE-EALLQTDYGLHRLLVKVSDHGYPEPLHSTVMVN 813

Query: 782 ILVTDVNDN 790
           + V D   N
Sbjct: 814 LFVNDTVSN 822



 Score =  182 bits (443), Expect = 1e-43
 Identities = 191/703 (27%), Positives = 302/703 (42%), Gaps = 66/703 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTV-LTLKATDQDIGKNAEVEYTI-ELVTA 67
           +I + D ND++P F + Q    V E A   T + +   A D D+G N    Y + +    
Sbjct: 169 KIAIRDINDNAPQFPVSQISVWVPENAPVNTRLAIEHPAVDPDVGINGVQTYRLLDYHGM 228

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
            TL+ E+                    R+  L+   +LDRE   +Y  ++ A D  SP  
Sbjct: 229 FTLDVEENENGE---------------RTPYLIVMGALDRETQDQYVSIIIAEDGGSPP- 272

Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
             L  +AT+ + I D NDN P F++    V+V  + +V     IA ++A D D+G N+ I
Sbjct: 273 --LLGSATLTIGISDINDNCPLFTDSQINVTVYGNATV--GTPIAAVQAVDKDLGTNAQI 328

Query: 188 RYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS-PSRSNTTQL 243
            Y+    +   ++  F +D  +G + L   +    + S++L I A   G  P+       
Sbjct: 329 TYSYSQKVPQASKDLFHLDENTGVIKLFSKIGGSVLESHKLTILANGPGCIPAVITALVS 388

Query: 244 LIN-IRDVNDNAPRFYTS------LFQESVSENVPIGYSIVR--VQAYDADEGVNAELTY 294
           +I  I    +  PR+  +        +E    N PI +  +R     Y  +  ++ E  +
Sbjct: 389 IIKVIFRPPEIVPRYIANEIDGVVYLKELEPVNTPIAFFTIRDPEGKYKVNCYLDGEGPF 448

Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354
            ++      N  L  T  P          +D E Q  Y++ V A +              
Sbjct: 449 RLSPYKPYNNEYLLETTKP----------MDYELQQFYEVAVVAWN--SEGFHVKRVIKV 496

Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYE-ITGGNTRGRFS 413
                      F+    E+ + E+  P   +  L ATDAD + R       G +    FS
Sbjct: 497 QLLDDNDNAPIFLQPLIELTIEENNSPNAFLTKLYATDADSEERGQVSYFLGPDAPSYFS 556

Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFEN 471
           + S    G++TV+  LD +++ +Y  TV A D G   R   A V + + D N+ +P F N
Sbjct: 557 LDSVT--GILTVSTQLDREEKEKYRYTVRAVDCGKPPRESVATVALTVLDKNDNSPRFIN 614

Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
             ++  V E+ P    + V+S TD+D G N  +  S         V +    FVI+   G
Sbjct: 615 KDFSFFVPENFPGYGEIGVISVTDADAGRNGWVALS---------VVNQSDIFVIDTGKG 665

Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP--VFKQ-QLYTA 588
            +     LDRE  S Y L V A DGG P+LS T  + I ++D+NDN P  +F Q  +   
Sbjct: 666 MLRAKVSLDREQQSSYTLWVEAVDGGEPALSSTAKITILLLDINDNPPLVLFPQSNMSYL 725

Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGVIRTNKALDR 647
            ++   L G+ V++V A D D G+N  I Y  +  +     SF IDP +G I   +AL +
Sbjct: 726 LVLPSTLPGSPVTEVYAVDKDTGMNAVIAYSIIGRRGPRPESFRIDPKTGNITLEEALLQ 785

Query: 648 ESVATHDLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFES 689
                H L     D G P P  STV+V++ + D   +    ES
Sbjct: 786 TDYGLHRLLVKVSDHGYPEPLHSTVMVNLFVNDTVSNESYIES 828



 Score =  169 bits (410), Expect = 1e-39
 Identities = 166/647 (25%), Positives = 271/647 (41%), Gaps = 37/647 (5%)

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSI-VRVQAYDADEGVNAELTYTMTDKDYTG 303
           I IRD+NDNAP+F  S     V EN P+   + +   A D D G+N   TY + D  Y G
Sbjct: 170 IAIRDINDNAPQFPVSQISVWVPENAPVNTRLAIEHPAVDPDVGINGVQTYRLLD--YHG 227

Query: 304 NVDLPITIDP---RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
              L +  +    R+ ++   G LDRETQ +Y  ++ A DGG PP   +AT         
Sbjct: 228 MFTLDVEENENGERTPYLIVMGALDRETQDQYVSIIIAEDGGSPPLLGSATLTIGISDIN 287

Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITS-Q 417
                F   Q  V +  +   GTP+  + A D D   + ++ Y  +    +    +    
Sbjct: 288 DNCPLFTDSQINVTVYGNATVGTPIAAVQAVDKDLGTNAQITYSYSQKVPQASKDLFHLD 347

Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQIN--ITDANNYAPVFENAP 473
              G+I +   +       + LT+ A   G      TA+V I   I       P +    
Sbjct: 348 ENTGVIKLFSKIGGSVLESHKLTILANGPGCIPAVITALVSIIKVIFRPPEIVPRYIANE 407

Query: 474 YTASVF--EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
               V+  E  P+ T +   +  D +        Y ++  +  E           N +  
Sbjct: 408 IDGVVYLKELEPVNTPIAFFTIRDPEG------KYKVNCYLDGEGPFRLSPYKPYNNEY- 460

Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
            + T K +D E    Y + V A +           +++ ++D NDN P+F Q L    I 
Sbjct: 461 LLETTKPMDYELQQFYEVAVVAWNS--EGFHVKRVIKVQLLDDNDNAPIFLQPLIELTIE 518

Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA 651
           E+      ++++ ATDAD    G++ Y L P       F +D  +G++  +  LDRE   
Sbjct: 519 ENNSPNAFLTKLYATDADSEERGQVSYFLGPD--APSYFSLDSVTGILTVSTQLDREEKE 576

Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711
            +     A+D G PP+ S   V + + D ND+ P F +   +F++ EN P    IG I  
Sbjct: 577 KYRYTVRAVDCGKPPRESVATVALTVLDKNDNSPRFINKDFSFFVPENFPGYGEIGVISV 636

Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771
            D D G N  V  S+   + S+ F ++T +G  +A++   +D + +S    +   +    
Sbjct: 637 TDADAGRNGWVALSVV--NQSDIFVIDTGKGMLRAKV--SLDREQQSSYTLWVEAVDGGE 692

Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN---YKDCFPVGPFGRVPAYDAD--VTDK 826
           P L +  ++ IL+ D+NDN P++   Q   +         P  P   V A D D  +   
Sbjct: 693 PALSSTAKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGSPVTEVYAVDKDTGMNAV 752

Query: 827 LQYRILS--GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
           + Y I+   G       ++  TG++TL   L      L  + V V+D
Sbjct: 753 IAYSIIGRRGPRPESFRIDPKTGNITLEEALLQTDYGLHRLLVKVSD 799



 Score = 89.8 bits (213), Expect = 9e-16
 Identities = 78/266 (29%), Positives = 126/266 (47%), Gaps = 33/266 (12%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + VLD ND+SP F  + +   V E       +  +  TD D G+N  V  ++       +
Sbjct: 600 LTVLDKNDNSPRFINKDFSFFVPENFPGYGEIGVISVTDADAGRNGWVALSV-------V 652

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           N  D              +F ID   G L  + SLDRE+ + YT+ V+A D   P    L
Sbjct: 653 NQSD--------------IFVIDTGKGMLRAKVSLDREQQSSYTLWVEAVDGGEPA---L 695

Query: 131 SSTATIHVNIIDDNDNYP--QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
           SSTA I + ++D NDN P   F +   +  +    ++  +PV  ++ A D D G N+ I 
Sbjct: 696 SSTAKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGSPV-TEVYAVDKDTGMNAVIA 754

Query: 189 YAIIG--GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           Y+IIG  G     F ID  +G+++L + L       +RL+++  D G P   ++T +++N
Sbjct: 755 YSIIGRRGPRPESFRIDPKTGNITLEEALLQTDYGLHRLLVKVSDHGYPEPLHST-VMVN 813

Query: 247 IRDVNDNAPR--FYTSLFQESVSENV 270
           +  VND      +  SL ++    N+
Sbjct: 814 L-FVNDTVSNESYIESLLRKEPEINI 838



 Score = 78.2 bits (184), Expect = 3e-12
 Identities = 62/226 (27%), Positives = 105/226 (46%), Gaps = 10/226 (4%)

Query: 671 VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG-EIRAHDPDEGPNAVVHYSIKGG 729
           V V I I DIND+ P F    ++ ++ EN+P+ T +  E  A DPD G N V  Y +   
Sbjct: 166 VKVKIAIRDINDNAPQFPVSQISVWVPENAPVNTRLAIEHPAVDPDVGINGVQTYRLLDY 225

Query: 730 DDSNSFSLETRQGSDKAE-LVTMVDLDYESPRKKYELVIR--AASPPLWNDVRVEILVTD 786
               +  +E  +  ++   L+ M  LD E+  +   ++I     SPPL     + I ++D
Sbjct: 226 HGMFTLDVEENENGERTPYLIVMGALDRETQDQYVSIIIAEDGGSPPLLGSATLTIGISD 285

Query: 787 VNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQY-----RILSGNNANLIL 841
           +NDN P+  D QI    Y +     P   V A D D+    Q      + +   + +L  
Sbjct: 286 INDNCPLFTDSQINVTVYGNATVGTPIAAVQAVDKDLGTNAQITYSYSQKVPQASKDLFH 345

Query: 842 LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887
           L+E TG + L  ++  +V +   + + + +G   I A++   V +I
Sbjct: 346 LDENTGVIKLFSKIGGSVLESHKLTI-LANGPGCIPAVITALVSII 390


>UniRef50_UPI000155BF0A Cluster: PREDICTED: similar to protocadherin
           gamma B5; n=2; Ornithorhynchus anatinus|Rep: PREDICTED:
           similar to protocadherin gamma B5 - Ornithorhynchus
           anatinus
          Length = 1443

 Score =  242 bits (592), Expect = 1e-61
 Identities = 188/608 (30%), Positives = 274/608 (45%), Gaps = 28/608 (4%)

Query: 87  QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146
           + +F +   SG LL    +DRE++   TV      +A  V +   +   ++V I D NDN
Sbjct: 72  KQLFTVSADSGDLLVSHRIDREQICGKTVRCSILLEA--VVENPLNVFHVNVEIQDINDN 129

Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206
            P+F      + + E  S       A   A D DVG NS   Y ++  N    F +    
Sbjct: 130 PPRFRRNHIDLEISE--SAVSGASFALEPAQDPDVGINSLKNY-LLSTNPNFSFDVKETK 186

Query: 207 -----GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261
                 ++ + K LD E   SY LV+ A DGG P  S T ++ IN+ D NDNAP F   +
Sbjct: 187 DGNKYAELIVGKPLDRETQNSYHLVLTAVDGGDPVLSGTVEIRINVTDANDNAPVFSQDV 246

Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321
           ++ S+ E++P G  ++RV+A D DEG NA +T+  ++   T  V     +DP SG + T 
Sbjct: 247 YKVSLRESLPPGSPVLRVEATDKDEGANARVTFAFSNVAQT--VRHAFALDPVSGEISTK 304

Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381
           G LD E    Y L++ A DGG      T                F        + ED   
Sbjct: 305 GILDFEGIKGYSLVLEAKDGGGLVTQCTVEIEILDENDNAPEVTFT--SISSPIPEDSEL 362

Query: 382 GTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440
           GT +  +   D D  DN        G    +   +S N   L+T    LD +Q   Y +T
Sbjct: 363 GTVIALIRTRDRDSGDNGAVTCRIEGEIPFKIVSSSNNYYKLMT-DSVLDREQTAEYNIT 421

Query: 441 VSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498
           ++ATD G    + +  + + + D N+  PVF +  Y A V E+   G ++  VSA+D D+
Sbjct: 422 ITATDRGNPPLTTSKTISLLVADVNDNPPVFPHTTYVAYVPENNRPGASIFRVSASDRDL 481

Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558
             NA+I+YSL    S+E+         IN  +G I   +  D E    + L V A+D G 
Sbjct: 482 DSNARISYSLLD--SSESELPLSSSVSINSHSGDIYAQRSFDYEQFRAFELHVQAQDSGS 539

Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQQLYTAN-------IMEDALVGTSVSQVGATDADVG 611
           P L     V + +VD NDN P         +       +   A  G  VS+V A DAD G
Sbjct: 540 PPLRANVTVRVFIVDQNDNAPRILYPALEPDGSALFDMVPRSAEPGYLVSKVVAVDADSG 599

Query: 612 LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671
            N  + Y +  +  + G F +   +G IRT +AL     + H L     DGG PP SSTV
Sbjct: 600 PNAWLAYHV-LQASDPGLFSLGLRTGEIRTARALADGDPSRHRLLVAVRDGGQPPLSSTV 658

Query: 672 IVHIKIED 679
            +H+   D
Sbjct: 659 ALHLVFAD 666



 Score =  219 bits (534), Expect = 1e-54
 Identities = 172/581 (29%), Positives = 270/581 (46%), Gaps = 36/581 (6%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQ---NGRG 421
           F     ++E++E    G       A D D   N L   +   N    F +      N   
Sbjct: 133 FRRNHIDLEISESAVSGASFALEPAQDPDVGINSLKNYLLSTNPNFSFDVKETKDGNKYA 192

Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVF 479
            + V +PLD + +  Y L ++A D G    S T  ++IN+TDAN+ APVF    Y  S+ 
Sbjct: 193 ELIVGKPLDRETQNSYHLVLTAVDGGDPVLSGTVEIRINVTDANDNAPVFSQDVYKVSLR 252

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           E  P G+ VL V ATD D G NA++T++ S+    + V H    F ++P +G I+T  +L
Sbjct: 253 ESLPPGSPVLRVEATDKDEGANARVTFAFSNVA--QTVRH---AFALDPVSGEISTKGIL 307

Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
           D E + GY L + A+DGG   L     VEI ++D NDN P       ++ I ED+ +GT 
Sbjct: 308 DFEGIKGYSLVLEAKDGG--GLVTQCTVEIEILDENDNAPEVTFTSISSPIPEDSELGTV 365

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG---VIRTNKALDRESVATHDLK 656
           ++ +   D D G NG +   ++     E  F I  +S     + T+  LDRE  A +++ 
Sbjct: 366 IALIRTRDRDSGDNGAVTCRIEG----EIPFKIVSSSNNYYKLMTDSVLDREQTAEYNIT 421

Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
             A D G PP +++  + + + D+ND+PPVF       Y+ EN+  G +I  + A D D 
Sbjct: 422 ITATDRGNPPLTTSKTISLLVADVNDNPPVFPHTTYVAYVPENNRPGASIFRVSASDRDL 481

Query: 717 GPNAVVHYSIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASP 772
             NA + YS+    +S    S      S   ++      DYE  R  +EL ++A    SP
Sbjct: 482 DSNARISYSLLDSSESELPLSSSVSINSHSGDIYAQRSFDYEQFR-AFELHVQAQDSGSP 540

Query: 773 PLWNDVRVEILVTDVNDNAP------VMKDFQIIFNNY-KDCFPVGPFGRVPAYDADVTD 825
           PL  +V V + + D NDNAP      +  D   +F+   +   P     +V A DAD   
Sbjct: 541 PLRANVTVRVFIVDQNDNAPRILYPALEPDGSALFDMVPRSAEPGYLVSKVVAVDADSGP 600

Query: 826 K--LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLS 883
              L Y +L  ++  L  L   TG +  +  L    P    + V+V DG  +      ++
Sbjct: 601 NAWLAYHVLQASDPGLFSLGLRTGEIRTARALADGDPSRHRLLVAVRDG-GQPPLSSTVA 659

Query: 884 VRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAII 924
           + L+  + L  ++   L+D +A       + FF+    AI+
Sbjct: 660 LHLVFADSLQEALP-ELSDRSAPSDSQSKVNFFLVIALAIV 699



 Score =  164 bits (398), Expect = 4e-38
 Identities = 136/468 (29%), Positives = 212/468 (45%), Gaps = 42/468 (8%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +INV D ND++PVF    Y+ S+RE    G+ VL ++ATD+D G NA V +    V A T
Sbjct: 229 RINVTDANDNAPVFSQDVYKVSLRESLPPGSPVLRVEATDKDEGANARVTFAFSNV-AQT 287

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                           V+  F +D  SG + T+  LD E +  Y+++++A D        
Sbjct: 288 ----------------VRHAFALDPVSGEISTKGILDFEGIKGYSLVLEAKDGGG----- 326

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           L +  T+ + I+D+NDN P+ +  + +  + ED  +    VIA I+  D D G N A+  
Sbjct: 327 LVTQCTVEIEILDENDNAPEVTFTSISSPIPEDSEL--GTVIALIRTRDRDSGDNGAVTC 384

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            I G   ++ F I S S +   + T   LD EQ   Y + I A D G+P  + +  + + 
Sbjct: 385 RIEG---EIPFKIVSSSNNYYKLMTDSVLDREQTAEYNITITATDRGNPPLTTSKTISLL 441

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NV 305
           + DVNDN P F  + +   V EN   G SI RV A D D   NA ++Y++ D   +   +
Sbjct: 442 VADVNDNPPVFPHTTYVAYVPENNRPGASIFRVSASDRDLDSNARISYSLLDSSESELPL 501

Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
              ++I+  SG +Y     D E    ++L V A D G PP  A  T              
Sbjct: 502 SSSVSINSHSGDIYAQRSFDYEQFRAFELHVQAQDSGSPPLRANVTVRVFIVDQNDNAPR 561

Query: 366 FMPGQYEVE-------LAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITS 416
            +    E +       +     PG  V  + A DAD      L Y +   +  G FS+  
Sbjct: 562 ILYPALEPDGSALFDMVPRSAEPGYLVSKVVAVDADSGPNAWLAYHVLQASDPGLFSLGL 621

Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANN 464
           + G   I  A+ L      R+ L V+  D G    ++ V +++  A++
Sbjct: 622 RTGE--IRTARALADGDPSRHRLLVAVRDGGQPPLSSTVALHLVFADS 667



 Score = 92.3 bits (219), Expect = 2e-16
 Identities = 69/228 (30%), Positives = 111/228 (48%), Gaps = 8/228 (3%)

Query: 601 SQVGATDADVGLNGR-IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK-AV 658
           S VG    D+GLN R +         E+  F +   SG +  +  +DRE +    ++ ++
Sbjct: 45  SVVGHLARDLGLNIREVSGRKLRVSAEKQLFTVSADSGDLLVSHRIDREQICGKTVRCSI 104

Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
            ++       +   V+++I+DIND+PP F  + +   ISE++  G +     A DPD G 
Sbjct: 105 LLEAVVENPLNVFHVNVEIQDINDNPPRFRRNHIDLEISESAVSGASFALEPAQDPDVGI 164

Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLW 775
           N++ +Y +    + +    ET+ G+  AEL+    LD E+ +  Y LV+ A     P L 
Sbjct: 165 NSLKNYLLSTNPNFSFDVKETKDGNKYAELIVGKPLDRET-QNSYHLVLTAVDGGDPVLS 223

Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD 822
             V + I VTD NDNAPV     +   + ++  P G P  RV A D D
Sbjct: 224 GTVEIRINVTDANDNAPVFSQ-DVYKVSLRESLPPGSPVLRVEATDKD 270



 Score = 91.5 bits (217), Expect = 3e-16
 Identities = 62/231 (26%), Positives = 113/231 (48%), Gaps = 20/231 (8%)

Query: 127  SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
            S  LSS  T+ +N+ D NDN P F  +++ V V E+       ++  + A+D D G N  
Sbjct: 1022 SPPLSSQRTVSLNVSDVNDNAPAFFRRSHEVFVQENNR--PGVLLCSLAASDPDSGLNGL 1079

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            I Y+++    +        +G V   ++ DYEQ ++ +  ++A+D G P  S+T  + + 
Sbjct: 1080 IAYSLLEPRGRE-------TGAVHAARSFDYEQTQTLQFEVQARDRGEPPLSSTVTVRLF 1132

Query: 247  IRDVNDNAPRFYT------SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
            I DVNDNAP          +L  +++  +   G+ + +V A D D G NA ++Y +    
Sbjct: 1133 ILDVNDNAPAVLRPQARPGALCPQALPPSASAGHLVTKVTAVDLDSGYNAWVSYQL---- 1188

Query: 301  YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
            +         +   +G + T+G +  +   + +L++   D G+PP S + T
Sbjct: 1189 FEAPDPTLFAVSRYAGEIRTAGPIPADLPPQ-RLVIMVQDSGNPPLSTSVT 1238



 Score = 89.4 bits (212), Expect = 1e-15
 Identities = 68/237 (28%), Positives = 106/237 (44%), Gaps = 19/237 (8%)

Query: 557  GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616
            G P LS    V ++V DVNDN P F ++ +   + E+   G  +  + A+D D GLNG I
Sbjct: 1021 GSPPLSSQRTVSLNVSDVNDNAPAFFRRSHEVFVQENNRPGVLLCSLAASDPDSGLNGLI 1080

Query: 617  HYE-LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675
             Y  L+P+ RE         +G +   ++ D E   T   +  A D G PP SSTV V +
Sbjct: 1081 AYSLLEPRGRE---------TGAVHAARSFDYEQTQTLQFEVQARDRGEPPLSSTVTVRL 1131

Query: 676  KIEDINDSPPVF------ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729
             I D+ND+ P                +  ++  G  + ++ A D D G NA V Y +   
Sbjct: 1132 FILDVNDNAPAVLRPQARPGALCPQALPPSASAGHLVTKVTAVDLDSGYNAWVSYQLFEA 1191

Query: 730  DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTD 786
             D   F++    G  +       DL    P++   +V  + +PPL   V + + + D
Sbjct: 1192 PDPTLFAVSRYAGEIRTAGPIPADL---PPQRLVIMVQDSGNPPLSTSVTLLVSLED 1245



 Score = 87.8 bits (208), Expect = 4e-15
 Identities = 72/244 (29%), Positives = 107/244 (43%), Gaps = 22/244 (9%)

Query: 442  SATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501
            S   S   S    V +N++D N+ AP F    +   V E+   G  +  ++A+D D G+N
Sbjct: 1018 STAGSPPLSSQRTVSLNVSDVNDNAPAFFRRSHEVFVQENNRPGVLLCSLAASDPDSGLN 1077

Query: 502  AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL 561
              I YSL      E              TGA+   +  D E        V ARD G P L
Sbjct: 1078 GLIAYSLLEPRGRE--------------TGAVHAARSFDYEQTQTLQFEVQARDRGEPPL 1123

Query: 562  SDTTDVEISVVDVNDNEP-VFKQQLYTANIMEDAL-----VGTSVSQVGATDADVGLNGR 615
            S T  V + ++DVNDN P V + Q     +   AL      G  V++V A D D G N  
Sbjct: 1124 SSTVTVRLFILDVNDNAPAVLRPQARPGALCPQALPPSASAGHLVTKVTAVDLDSGYNAW 1183

Query: 616  IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675
            + Y+L  +  +   F +   +G IRT   +  + +    L  +  D G PP S++V + +
Sbjct: 1184 VSYQLF-EAPDPTLFAVSRYAGEIRTAGPIPAD-LPPQRLVIMVQDSGNPPLSTSVTLLV 1241

Query: 676  KIED 679
             +ED
Sbjct: 1242 SLED 1245



 Score = 70.9 bits (166), Expect = 5e-10
 Identities = 62/243 (25%), Positives = 104/243 (42%), Gaps = 34/243 (13%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +NV D ND++P F  + +E  V+E    G  + +L A+D D G N  + Y++       L
Sbjct: 1033 LNVSDVNDNAPAFFRRSHEVFVQENNRPGVLLCSLAASDPDSGLNGLIAYSL-------L 1085

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             P                       +GA+    S D E+       V+A D+  P    L
Sbjct: 1086 EPRGR-------------------ETGAVHAARSFDYEQTQTLQFEVQARDRGEPP---L 1123

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSV--DEDI--SVTDNPVIAKIKATDADVGANSA 186
            SST T+ + I+D NDN P              + +  S +   ++ K+ A D D G N+ 
Sbjct: 1124 SSTVTVRLFILDVNDNAPAVLRPQARPGALCPQALPPSASAGHLVTKVTAVDLDSGYNAW 1183

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            + Y +        F++   +G++     +  + +   RLVI  QD G+P  S +  LL++
Sbjct: 1184 VSYQLFEAPDPTLFAVSRYAGEIRTAGPIPAD-LPPQRLVIMVQDSGNPPLSTSVTLLVS 1242

Query: 247  IRD 249
            + D
Sbjct: 1243 LED 1245



 Score = 68.5 bits (160), Expect = 2e-09
 Identities = 43/134 (32%), Positives = 66/134 (49%), Gaps = 13/134 (9%)

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
            G+PP SS   V + + D+ND+ P F       ++ EN+  G  +  + A DPD G N ++
Sbjct: 1021 GSPPLSSQRTVSLNVSDVNDNAPAFFRRSHEVFVQENNRPGVLLCSLAASDPDSGLNGLI 1080

Query: 723  HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIR-AASPPLWNDVRV 780
             YS+          LE R G +   +      DYE  +  ++E+  R    PPL + V V
Sbjct: 1081 AYSL----------LEPR-GRETGAVHAARSFDYEQTQTLQFEVQARDRGEPPLSSTVTV 1129

Query: 781  EILVTDVNDNAPVM 794
             + + DVNDNAP +
Sbjct: 1130 RLFILDVNDNAPAV 1143



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 49/171 (28%), Positives = 74/171 (43%), Gaps = 14/171 (8%)

Query: 181  VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240
            + A  A R A  G  T + F    L+  +S  +TL        +   +    GSP  S+ 
Sbjct: 972  LAAPRAKRAAAPGRQTSLPFG---LAARLSRGQTLKPALSSRCQTDSQRSTAGSPPLSSQ 1028

Query: 241  TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
              + +N+ DVNDNAP F+    +  V EN   G  +  + A D D G+N  + Y++ +  
Sbjct: 1029 RTVSLNVSDVNDNAPAFFRRSHEVFVQENNRPGVLLCSLAASDPDSGLNGLIAYSLLEP- 1087

Query: 301  YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
              G           +G V+ +   D E     Q  V A D G+PP S+T T
Sbjct: 1088 -RGR---------ETGAVHAARSFDYEQTQTLQFEVQARDRGEPPLSSTVT 1128



 Score = 56.0 bits (129), Expect = 1e-05
 Identities = 62/242 (25%), Positives = 96/242 (39%), Gaps = 27/242 (11%)

Query: 342  GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHY 401
            G PP S+  T              F    +EV + E+  PG  + +L A+D D       
Sbjct: 1021 GSPPLSSQRTVSLNVSDVNDNAPAFFRRSHEVFVQENNRPGVLLCSLAASDPD------- 1073

Query: 402  EITGGNTRGRFSITSQNGR--GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQI 457
              +G N    +S+    GR  G +  A+  D++Q +     V A D G    S T  V++
Sbjct: 1074 --SGLNGLIAYSLLEPRGRETGAVHAARSFDYEQTQTLQFEVQARDRGEPPLSSTVTVRL 1131

Query: 458  NITDANNYAPVF------ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE 511
             I D N+ AP          A    ++   A  G  V  V+A D D G NA ++Y L   
Sbjct: 1132 FILDVNDNAPAVLRPQARPGALCPQALPPSASAGHLVTKVTAVDLDSGYNAWVSYQLFE- 1190

Query: 512  ISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571
                  A     F ++   G I T   +  + +    L +  +D G P LS +  + +S+
Sbjct: 1191 ------APDPTLFAVSRYAGEIRTAGPIPAD-LPPQRLVIMVQDSGNPPLSTSVTLLVSL 1243

Query: 572  VD 573
             D
Sbjct: 1244 ED 1245


>UniRef50_UPI0000583D73 Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 1326

 Score =  242 bits (592), Expect = 1e-61
 Identities = 194/683 (28%), Positives = 311/683 (45%), Gaps = 42/683 (6%)

Query: 92  IDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQF 150
           +D ++G L T   LDRE++    + L +    A  +  R     T+ V I D ND+ P+F
Sbjct: 72  LDSQTGELTTVLDLDREELCPGSSALCEIEVNAIELGTR--EVITVKVTINDINDHAPEF 129

Query: 151 SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS------AIRYAIIGGNTQMQFSIDS 204
            +    +S+ E  SV          A+D D+G N+      +  YA   G  Q +F    
Sbjct: 130 RDDLTNMSIPE--SVVPGTRFPLSTASDEDIGENAIQGYRLSDEYAETFGLVQNEFPGGL 187

Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
           +   + ++ +LD E   +Y + + A DGG P  S  T L + + D +D++P F  + +Q 
Sbjct: 188 IIIQLEVIGSLDRENKDNYVMTLYADDGGDPVLSGVTTLNVTVLDSDDHSPVFDRTSYQV 247

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
           SV+EN+ +G  I++V+A D D G N ++ Y          ++L   ID  SGW+    +L
Sbjct: 248 SVAENIGVGQHIIQVRASDPDTGTNGQIIYDFGGSVSAKIIEL-FEIDSESGWLSVKSEL 306

Query: 325 DRETQAKYQLLVTATDG-GDP-PRSATATXXXXXXXXXXXXXXFMP----GQYEVELAED 378
           D E ++ +Q+ + AT+   +P P   T T                     G+++  +AE+
Sbjct: 307 DFEDESSHQVSIRATNNVPNPLPDFTTVTVNLIDVNDNKPRLTISALGDGGRFK-HIAEN 365

Query: 379 EPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITS-QNGRGLITVAQPLDFKQERRY 437
            P    V  +  TD D        +T  +  G F + S + G+  +  A  LD +    Y
Sbjct: 366 SPEDVDVAYVRVTDMDTGVNGQAILTLEDDFGHFYLESFREGQYFLKTAGVLDREDIDFY 425

Query: 438 VLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495
            +T+ A D G    S      + + D N+ +P+F ++ Y A++ E+   G  V  V A D
Sbjct: 426 NITILAEDRGSPVLSSRRRFAVFVDDENDNSPIFSSSVYHATISENNEPGHRVATVQAID 485

Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555
            D   N ++ YSL  +         D  F I+P  G +T N  LDRE      L + A D
Sbjct: 486 KDELENGEVVYSLLDD--------KDGSFGIHPFNGVLTANVSLDREDGESIDLMIRACD 537

Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615
            G P       + + V+D+NDN P F   L    I E+   GT V +  ATDAD G NGR
Sbjct: 538 RGQPQGCSDVPLTVRVLDMNDNGPTFGGDLIEMRIDENKPSGTIVGRAVATDADEGDNGR 597

Query: 616 IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675
           + Y +      +  F ID  SG I +   LDRE    +     A+D G  P+++T  V +
Sbjct: 598 LRYSI----LTDAVFRIDEDSGRIYSTAELDREIQELYHFTVRAVDDGLSPKTATATVVV 653

Query: 676 KIEDINDSPPVF---ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732
            + D ND  P F    +     +I  ++  G  I  + + D D+  NA V Y+I  G+ +
Sbjct: 654 TVNDGNDHSPEFIVPSAKNDIRFIPVSADPGLHIMTVESEDEDKDENAAVSYAISHGNTN 713

Query: 733 NSFSLETRQGSDKAELVTMVDLD 755
            +F ++        ++VT  DL+
Sbjct: 714 GAFGIQA-----NGQVVTAQDLE 731



 Score =  226 bits (552), Expect = 8e-57
 Identities = 202/687 (29%), Positives = 302/687 (43%), Gaps = 59/687 (8%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ + D NDH+P F       S+ E    GT      A+D+DIG+NA   Y +    A+T
Sbjct: 116 KVTINDINDHAPEFRDDLTNMSIPESVVPGTRFPLSTASDEDIGENAIQGYRLSDEYAET 175

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                           VQ+ F        L    SLDRE    Y + + A D   PV   
Sbjct: 176 FG-------------LVQNEFPGGLIIIQLEVIGSLDRENKDNYVMTLYADDGGDPV--- 219

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           LS   T++V ++D +D+ P F   +Y VSV E+I V  +  I +++A+D D G N  I Y
Sbjct: 220 LSGVTTLNVTVLDSDDHSPVFDRTSYQVSVAENIGVGQH--IIQVRASDPDTGTNGQIIY 277

Query: 190 AIIGGNTQMQ----FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
              GG+   +    F IDS SG +S+   LD+E   S+++ IRA +       + T + +
Sbjct: 278 DF-GGSVSAKIIELFEIDSESGWLSVKSELDFEDESSHQVSIRATNNVPNPLPDFTTVTV 336

Query: 246 NIRDVNDNAPRFYTSLFQES-----VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
           N+ DVNDN PR   S   +      ++EN P    +  V+  D D GVN +   T+ D D
Sbjct: 337 NLIDVNDNKPRLTISALGDGGRFKHIAENSPEDVDVAYVRVTDMDTGVNGQAILTLED-D 395

Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
           + G+  L  +      ++ T+G LDRE    Y + + A D G P  S+            
Sbjct: 396 F-GHFYLE-SFREGQYFLKTAGVLDREDIDFYNITILAEDRGSPVLSSRRRFAVFVDDEN 453

Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQN 418
                F    Y   ++E+  PG  V T+ A D DE  +  + Y +      G F I   N
Sbjct: 454 DNSPIFSSSVYHATISENNEPGHRVATVQAIDKDELENGEVVYSLLDDKD-GSFGIHPFN 512

Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYT 475
           G  ++T    LD +      L + A D G   G SD  +  + + D N+  P F      
Sbjct: 513 G--VLTANVSLDREDGESIDLMIRACDRGQPQGCSDVPLT-VRVLDMNDNGPTFGGDLIE 569

Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
             + E+ P GT V    ATD+D G N ++ YS+ +          D  F I+  +G I +
Sbjct: 570 MRIDENKPSGTIVGRAVATDADEGDNGRLRYSILT----------DAVFRIDEDSGRIYS 619

Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF-----KQQLYTANI 590
              LDRE    Y  TV A D G+   + T  V ++V D ND+ P F     K  +    +
Sbjct: 620 TAELDREIQELYHFTVRAVDDGLSPKTATATVVVTVNDGNDHSPEFIVPSAKNDIRFIPV 679

Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650
             D   G  +  V + D D   N  + Y +       G+F I  A+G + T + L+    
Sbjct: 680 SADP--GLHIMTVESEDEDKDENAAVSYAIS-HGNTNGAFGIQ-ANGQVVTAQDLEPMWE 735

Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKI 677
             HD+   A DGG P  SST ++ + I
Sbjct: 736 GVHDITIRATDGGNPSASSTAVLRVVI 762



 Score =  225 bits (550), Expect = 1e-56
 Identities = 190/657 (28%), Positives = 295/657 (44%), Gaps = 47/657 (7%)

Query: 160 DEDISVTDNPVIAKIKATDADVGANSAIRYAIIG-GNTQMQFSIDSLSGDVSLVKTLDYE 218
           D D  V    VI  + A D  +  ++   ++++G  N     S+DS +G+++ V  LD E
Sbjct: 30  DIDEGVGPGTVIGNV-ADDLAITIDANTEFSMLGVPNETAYVSLDSQTGELTTVLDLDRE 88

Query: 219 QV--RSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSI 276
           ++   S  L     +           + + I D+ND+AP F   L   S+ E+V  G   
Sbjct: 89  ELCPGSSALCEIEVNAIELGTREVITVKVTINDINDHAPEFRDDLTNMSIPESVVPGTRF 148

Query: 277 VRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS----GQLDRETQAKY 332
               A D D G NA   Y ++D +Y     L     P  G +       G LDRE +  Y
Sbjct: 149 PLSTASDEDIGENAIQGYRLSD-EYAETFGLVQNEFP-GGLIIIQLEVIGSLDRENKDNY 206

Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392
            + + A DGGDP  S   T              F    Y+V +AE+   G  ++ + A+D
Sbjct: 207 VMTLYADDGGDPVLSGVTTLNVTVLDSDDHSPVFDRTSYQVSVAENIGVGQHIIQVRASD 266

Query: 393 ADE--DNRLHYEITGGNTRGR----FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446
            D   + ++ Y+  GG+   +    F I S++G   ++V   LDF+ E  + +++ AT++
Sbjct: 267 PDTGTNGQIIYDF-GGSVSAKIIELFEIDSESG--WLSVKSELDFEDESSHQVSIRATNN 323

Query: 447 --GGRSDTAMVQINITDANNYAP-----VFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499
                 D   V +N+ D N+  P        +      + E++P    V  V  TD D G
Sbjct: 324 VPNPLPDFTTVTVNLIDVNDNKPRLTISALGDGGRFKHIAENSPEDVDVAYVRVTDMDTG 383

Query: 500 INAQITYSLSSEISNEAV-AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558
           +N Q   +L  +  +  + +  + Q+ +        T  +LDRE +  Y +T+ A D G 
Sbjct: 384 VNGQAILTLEDDFGHFYLESFREGQYFLK-------TAGVLDREDIDFYNITILAEDRGS 436

Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618
           P LS      + V D NDN P+F   +Y A I E+   G  V+ V A D D   NG + Y
Sbjct: 437 PVLSSRRRFAVFVDDENDNSPIFSSSVYHATISENNEPGHRVATVQAIDKDELENGEVVY 496

Query: 619 ELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678
            L   D ++GSF I P +GV+  N +LDRE   + DL   A D G P   S V + +++ 
Sbjct: 497 SL--LDDKDGSFGIHPFNGVLTANVSLDREDGESIDLMIRACDRGQPQGCSDVPLTVRVL 554

Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738
           D+ND+ P F  D +   I EN P GT +G   A D DEG N  + YSI        F ++
Sbjct: 555 DMNDNGPTFGGDLIEMRIDENKPSGTIVGRAVATDADEGDNGRLRYSIL---TDAVFRID 611

Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAP 792
                D   + +  +LD E  ++ Y   +RA      P      V + V D ND++P
Sbjct: 612 ----EDSGRIYSTAELDREI-QELYHFTVRAVDDGLSPKTATATVVVTVNDGNDHSP 663



 Score =  141 bits (342), Expect = 2e-31
 Identities = 112/369 (30%), Positives = 174/369 (47%), Gaps = 24/369 (6%)

Query: 439 LTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498
           + V+A + G R +   V++ I D N++AP F +     S+ E    GT   + +A+D D+
Sbjct: 100 IEVNAIELGTR-EVITVKVTINDINDHAPEFRDDLTNMSIPESVVPGTRFPLSTASDEDI 158

Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558
           G NA   Y LS E + E       +F        +     LDRE    Y++T+ A DGG 
Sbjct: 159 GENAIQGYRLSDEYA-ETFGLVQNEFPGGLIIIQLEVIGSLDRENKDNYVMTLYADDGGD 217

Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618
           P LS  T + ++V+D +D+ PVF +  Y  ++ E+  VG  + QV A+D D G NG+I Y
Sbjct: 218 PVLSGVTTLNVTVLDSDDHSPVFDRTSYQVSVAENIGVGQHIIQVRASDPDTGTNGQIIY 277

Query: 619 ELDPKDREE--GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676
           +       +    F ID  SG +     LD E  ++H +   A +    P      V + 
Sbjct: 278 DFGGSVSAKIIELFEIDSESGWLSVKSELDFEDESSHQVSIRATNNVPNPLPDFTTVTVN 337

Query: 677 IEDINDSPPVFESDCL----TF-YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD 731
           + D+ND+ P      L     F +I+ENSP    +  +R  D D G N     +++  DD
Sbjct: 338 LIDVNDNKPRLTISALGDGGRFKHIAENSPEDVDVAYVRVTDMDTGVNGQAILTLE--DD 395

Query: 732 SNSFSLET-RQGS---DKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILV 784
              F LE+ R+G      A ++   D+D+      Y + I A    SP L +  R  + V
Sbjct: 396 FGHFYLESFREGQYFLKTAGVLDREDIDF------YNITILAEDRGSPVLSSRRRFAVFV 449

Query: 785 TDVNDNAPV 793
            D NDN+P+
Sbjct: 450 DDENDNSPI 458


>UniRef50_Q8TAB3 Cluster: Protocadherin-19 precursor; n=31;
           Euteleostomi|Rep: Protocadherin-19 precursor - Homo
           sapiens (Human)
          Length = 1148

 Score =  241 bits (589), Expect = 3e-61
 Identities = 175/543 (32%), Positives = 248/543 (45%), Gaps = 33/543 (6%)

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           + I+D+NDNAP F  +  +  +SE    G  I    AYD D G     TY +T  +  G 
Sbjct: 117 VEIKDLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFG- 175

Query: 305 VDLPITID-PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
           +++    D  R   +     LDRETQ+ Y   +TA DGGDPPR  T              
Sbjct: 176 LEIKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNN 235

Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGG-NTRGRFSITSQNGR 420
             F    Y V + E+ PP TPV+ L A+D DE  + ++ Y   G  N R R         
Sbjct: 236 PVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHS 295

Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTAS- 477
           GL+TV   LD+++   Y L V A D G  S  A   V +++ D N+  PV       +  
Sbjct: 296 GLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSEL 355

Query: 478 --VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
             V E AP G  + +V  +D D G+N ++   L   + N  V    Q++        I  
Sbjct: 356 VEVSESAPPGYVIALVRVSDRDSGLNGRVQCRL---LGN--VPFRLQEY---ESFSTILV 407

Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
           +  LDRE    Y LT+ ARDGGVP L       + + D NDN P F +  Y   + E+  
Sbjct: 408 DGRLDREQHDQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNT 467

Query: 596 VGTSVSQVGATDADVGLNGRIHYELDP---KDREEGSFV-IDPASGVIRTNKALDRESVA 651
            G  +  V A D D+GLNG + Y++ P   +D    ++V I+P SG I   ++ + E   
Sbjct: 468 PGAYLLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTK 527

Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL-----TFYISENSPIGTTI 706
             + K +A DGG P   S   V + I D+ND+ PV  +  L       YI  NS IG  +
Sbjct: 528 AFEFKVLAKDGGLPSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLV 587

Query: 707 GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV 766
             ++A D DEG N  V Y +  G D   F ++   G      V       ES +  YEL+
Sbjct: 588 TVVKAEDYDEGENGRVTYDMTEG-DRGFFEIDQVNGE-----VRTTRTFGESSKSSYELI 641

Query: 767 IRA 769
           + A
Sbjct: 642 VVA 644



 Score =  212 bits (518), Expect = 1e-52
 Identities = 181/609 (29%), Positives = 268/609 (44%), Gaps = 31/609 (5%)

Query: 92  IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151
           I+  SG L+T+  +DR+ + R +   K       +S  +     I V I D NDN P F 
Sbjct: 74  INPSSGLLVTKQKIDRDLLCRQSP--KCIISLEVMSSSME-ICVIKVEIKDLNDNAPSFP 130

Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNT---QMQFSID-SLSG 207
                + + E  + +    I    A D D G+     Y +        +++   D S   
Sbjct: 131 AAQIELEISE--AASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSRFA 188

Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
           ++ + K+LD E    Y   I A DGG P R  T  L I + D NDN P F  S +  SV 
Sbjct: 189 ELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYAVSVP 248

Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
           EN P    ++R+ A D DEG N ++ Y+          +L   IDP SG V  +G LD E
Sbjct: 249 ENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTREL-FQIDPHSGLVTVTGALDYE 307

Query: 328 TQAKYQLLVTATDGG--DPPRSATATXXXXXXXXXXXXXXFMPGQYE-VELAEDEPPGTP 384
               Y+L V A D G    P     T               +    E VE++E  PPG  
Sbjct: 308 EGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYV 367

Query: 385 VVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
           +  +  +D D   + R+   + G      F +        I V   LD +Q  +Y LT+ 
Sbjct: 368 IALVRVSDRDSGLNGRVQCRLLGNVP---FRLQEYESFSTILVDGRLDREQHDQYNLTIQ 424

Query: 443 ATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
           A D G           + ITD N+  P F    Y   V E+   G  +L VSA D D+G+
Sbjct: 425 ARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGL 484

Query: 501 NAQITYSL-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
           N  ++Y +  S++ +  V  +     INP +G I   +  + E    +   V A+DGG+P
Sbjct: 485 NGSVSYQIVPSQVRDMPVFTY---VSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLP 541

Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLY---TAN--IMEDALVGTSVSQVGATDADVGLNG 614
           SL     V + ++DVNDN PV         TA   I  ++ +G  V+ V A D D G NG
Sbjct: 542 SLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGENG 601

Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674
           R+ Y++   DR  G F ID  +G +RT +     S ++++L  VA D G    S++ +V 
Sbjct: 602 RVTYDMTEGDR--GFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVL 659

Query: 675 IKIEDINDS 683
           I +    D+
Sbjct: 660 IYLSPALDA 668



 Score =  164 bits (399), Expect = 3e-38
 Identities = 130/443 (29%), Positives = 200/443 (45%), Gaps = 22/443 (4%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGL- 422
           F   Q E+E++E   PGT +   +A D D  +     YE+T     G    T  +G    
Sbjct: 129 FPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSRFA 188

Query: 423 -ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVF 479
            + V + LD + +  Y   ++A D G   R  T  + I +TD+N+  PVF  + Y  SV 
Sbjct: 189 ELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYAVSVP 248

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           E++P  T V+ ++A+D D G N Q+ YS    +++       + F I+P +G +T    L
Sbjct: 249 ENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRT----RELFQIDPHSGLVTVTGAL 304

Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME---DALV 596
           D E    Y L V A+D G  S+     V +SV+D NDN PV       + ++E    A  
Sbjct: 305 DYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPP 364

Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
           G  ++ V  +D D GLNGR+   L              +   I  +  LDRE    ++L 
Sbjct: 365 GYVIALVRVSDRDSGLNGRVQCRL--LGNVPFRLQEYESFSTILVDGRLDREQHDQYNLT 422

Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
             A DGG P   S     + I D ND+ P F        + EN+  G  +  + A DPD 
Sbjct: 423 IQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDL 482

Query: 717 GPNAVVHYSIKGGD--DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--- 771
           G N  V Y I      D   F+  +    +  ++  +   ++E   K +E  + A     
Sbjct: 483 GLNGSVSYQIVPSQVRDMPVFTYVSIN-PNSGDIYALRSFNHEQT-KAFEFKVLAKDGGL 540

Query: 772 PPLWNDVRVEILVTDVNDNAPVM 794
           P L ++  V +++ DVNDN PV+
Sbjct: 541 PSLQSNATVRVIILDVNDNTPVI 563



 Score =  147 bits (357), Expect = 3e-33
 Identities = 133/465 (28%), Positives = 201/465 (43%), Gaps = 38/465 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V D ND++PVF    Y  SV E +   T V+ L A+D D G N +V Y+      D  
Sbjct: 226 IKVTDSNDNNPVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDR- 284

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           +++F+ID  SG +    +LD E+   Y + V+A D   P S  +
Sbjct: 285 ---------------TRELFQIDPHSGLVTVTGALDYEEGHVYELDVQAKD-LGPNS--I 326

Query: 131 SSTATIHVNIIDDNDNYP---QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
            +   + V+++D NDN P     S  +  V V E  S     VIA ++ +D D G N  +
Sbjct: 327 PAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSE--SAPPGYVIALVRVSDRDSGLNGRV 384

Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
           +  ++ GN   +         + +   LD EQ   Y L I+A+DGG P   +     + I
Sbjct: 385 QCRLL-GNVPFRLQEYESFSTILVDGRLDREQHDQYNLTIQARDGGVPMLQSAKSFTVLI 443

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NVD 306
            D NDN P F    +Q  V EN   G  ++ V A D D G+N  ++Y +         V 
Sbjct: 444 TDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLNGSVSYQIVPSQVRDMPVF 503

Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT-----XXXXXXXXXX 361
             ++I+P SG +Y     + E    ++  V A DGG P   + AT               
Sbjct: 504 TYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQSNATVRVIILDVNDNTPVI 563

Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419
                + G  EV +  +   G  V  + A D D  E+ R+ Y++T G+ RG F I   NG
Sbjct: 564 TAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRVTYDMTEGD-RGFFEIDQVNG 622

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDA 462
              +   +      +  Y L V A D G    S +A+V I ++ A
Sbjct: 623 E--VRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVLIYLSPA 665



 Score =  123 bits (297), Expect = 6e-26
 Identities = 119/432 (27%), Positives = 188/432 (43%), Gaps = 31/432 (7%)

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
           SV E+   GT +  V+    + G       + +  + + +  H      INP +G + T 
Sbjct: 28  SVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVSNSAPHLVD---INPSSGLLVTK 84

Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
           + +DR+ +             + S  +   +++ + D+NDN P F        I E A  
Sbjct: 85  QKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKDLNDNAPSFPAAQIELEISEAASP 144

Query: 597 GTSVSQVGATDADVGLNGRIHYELDP--------KDREEGSFVIDPASGVIRTNKALDRE 648
           GT +    A D D G  G   YEL P        K R +GS   +     +   K+LDRE
Sbjct: 145 GTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSRFAE-----LVVEKSLDRE 199

Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
           + + +  +  A+DGG PP+  TV + IK+ D ND+ PVF        + ENSP  T +  
Sbjct: 200 TQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYAVSVPENSPPNTPVIR 259

Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVI 767
           + A DPDEG N  V YS  G    N  + E  Q    + LVT+   LDYE     YEL +
Sbjct: 260 LNASDPDEGTNGQVVYSFYG--YVNDRTRELFQIDPHSGLVTVTGALDYEEGH-VYELDV 316

Query: 768 RA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN--NYKDCFPVG---PFGRVPAY 819
           +A       +    +V + V D NDN PV+    +        +  P G      RV   
Sbjct: 317 QAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYVIALVRVSDR 376

Query: 820 DADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKA 878
           D+ +  ++Q R+L GN    +   E+  ++ +  +L+        + +   D GV  +++
Sbjct: 377 DSGLNGRVQCRLL-GNVPFRLQEYESFSTILVDGRLDREQHDQYNLTIQARDGGVPMLQS 435

Query: 879 MMQLSVRLITEE 890
               +V LIT+E
Sbjct: 436 AKSFTV-LITDE 446


>UniRef50_Q5CCS6 Cluster: Af1-cadherin; n=1; Artemia
           franciscana|Rep: Af1-cadherin - Artemia sanfranciscana
           (Brine shrimp) (Artemia franciscana)
          Length = 1566

 Score =  239 bits (586), Expect = 6e-61
 Identities = 192/665 (28%), Positives = 318/665 (47%), Gaps = 51/665 (7%)

Query: 171 IAKIKATDADVGANSAIRYAIIGGNT-QMQFSIDSLSGDVSLVKTLDYEQVRSYRLV--- 226
           + K++A D D G    +RY II   + + QF+++S +G+++  K  D ++ +  +L+   
Sbjct: 131 VTKVEAYDPDQGPAGKVRYEIIRSQSAEKQFNVNSYTGEITTAKVFDRDEPKREKLLYVT 190

Query: 227 IRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE 286
           ++A D G P+        + I D NDNAP F  + ++E++ ++  +  +++RV A D DE
Sbjct: 191 VKAVDEGFPALDVLCTFSVTITDKNDNAPIFDKNDYRETIPQDSKVNQTVMRVAATDIDE 250

Query: 287 GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE-TQAKYQLLVTATDGGDPP 345
           G NA +TY++       ++D    IDP+SG++     ++ E    +++L+  A DGG P 
Sbjct: 251 GENARITYSLRANRDESDLDY-FQIDPQSGFIKLVKAIEAEKVDYQFELVAAARDGGTPS 309

Query: 346 RSATATXXXXXXXXXXXXXXFMP-GQYEVELAED-EPPGTPVVTLTATDADEDNRLHYEI 403
              TA               F     + +++ E     G P+VTL A    E   +++ +
Sbjct: 310 NETTAQVNIKVVSSNRRAPEFTEVPDHIIDIEESFNDFGRPIVTLRAVSNIEKPVVYFSL 369

Query: 404 TGGNTRGR-----FSITSQ-NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQI 457
             G T        F +  + NG   I +A+ LD++    Y L +   +    S   +V++
Sbjct: 370 VNGQTEDTNKEETFRLVERANGTMDIFLARKLDYETVSNYQLNIRVQNDFDVSAETIVRL 429

Query: 458 NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEA 516
            + D+N+  P F +   + SV E++ + T VL + A D D    N ++TY L S      
Sbjct: 430 RVLDSNDEIPSFIDIE-SGSVLENSAVQTFVLRIRAIDKDGTSPNNKVTYRLLSNTDT-- 486

Query: 517 VAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL-SD------TTDVEI 569
                  F I+ +TG I T K LDRE  S Y +TV A+DG   SL SD          ++
Sbjct: 487 -------FSIDSETGEIRTLKRLDREETSSYAVTVQAQDGAPSSLRSDGLPNMYQKKFKV 539

Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629
            V+D NDN P F+Q  Y A I EDA + + V +V A D D      I Y++   +  + +
Sbjct: 540 EVLDQNDNPPRFEQPTYNAEIAEDADINSKVIEVTARDKDDF--AVIRYDITDGN-VDNA 596

Query: 630 FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES 689
           F+++  SGVIR N  LD E +  + L+  A DG     S    VH+ I ++ND+PP+FE+
Sbjct: 597 FMVEEKSGVIRVNNQLDYEKITDYYLRVRASDG---IHSDEATVHVSISNVNDNPPIFEN 653

Query: 690 ---DCLTFYISENSPIGTTIGEIRAHDPD---EGPNAVVHYSI-KGGDDSNSFSLETRQG 742
                +   I E       I +I   DPD    G N  + +S+ + G  +  F + T +G
Sbjct: 654 MQNPHVVRNIIEEEKRPDPIAKITVRDPDWDKGGKNPYITFSLDRTGQYAKHFRI-TPEG 712

Query: 743 SDKAELVTMVDLDYESPRKKYELVIRAASPPLW----NDVRVEILVTDVNDNAPVMKDFQ 798
               +     D     P+ +  ++      P      N + VEI + D+NDNAP +   Q
Sbjct: 713 ELFLDKGIDRDPPNGYPQARVNIIAEDRLEPNGKVQSNTLVVEIHLDDINDNAPFLNMEQ 772

Query: 799 -IIFN 802
            ++FN
Sbjct: 773 PVVFN 777



 Score =  234 bits (573), Expect = 2e-59
 Identities = 314/1247 (25%), Positives = 508/1247 (40%), Gaps = 138/1247 (11%)

Query: 29   EASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQD 88
            E S+ EG ++GT V  ++A D D G   +V Y  E++ + +   +               
Sbjct: 118  ETSIPEGENAGTFVTKVEAYDPDQGPAGKVRY--EIIRSQSAEKQ--------------- 160

Query: 89   VFRIDGRSGALLTRASLDREKVARYTVL---VKATDQASPVSDRLSSTATIHVNIIDDND 145
             F ++  +G + T    DR++  R  +L   VKA D+  P  D L    T  V I D ND
Sbjct: 161  -FNVNSYTGEITTAKVFDRDEPKREKLLYVTVKAVDEGFPALDVL---CTFSVTITDKND 216

Query: 146  NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ---FSI 202
            N P F +  Y  ++ +D  V  N  + ++ ATD D G N+ I Y++     +     F I
Sbjct: 217  NAPIFDKNDYRETIPQDSKV--NQTVMRVAATDIDEGENARITYSLRANRDESDLDYFQI 274

Query: 203  DSLSGDVSLVKTLDYEQV-RSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261
            D  SG + LVK ++ E+V   + LV  A+DGG+PS   T Q+ I +   N  AP F T +
Sbjct: 275  DPQSGFIKLVKAIEAEKVDYQFELVAAARDGGTPSNETTAQVNIKVVSSNRRAPEF-TEV 333

Query: 262  FQE--SVSENV-PIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW- 317
                  + E+    G  IV ++A    E      +      + T   +    ++  +G  
Sbjct: 334  PDHIIDIEESFNDFGRPIVTLRAVSNIEKPVVYFSLVNGQTEDTNKEETFRLVERANGTM 393

Query: 318  -VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376
             ++ + +LD ET + YQL +   +  D   SA                 F+  +    + 
Sbjct: 394  DIFLARKLDYETVSNYQLNIRVQNDFDV--SAETIVRLRVLDSNDEIPSFIDIE-SGSVL 450

Query: 377  EDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ 433
            E+    T V+ + A D D    +N++ Y +   NT   FSI S+ G   I   + LD ++
Sbjct: 451  ENSAVQTFVLRIRAIDKDGTSPNNKVTYRLL-SNT-DTFSIDSETGE--IRTLKRLDREE 506

Query: 434  ERRYVLTVSATD---SGGRSD------TAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
               Y +TV A D   S  RSD          ++ + D N+  P FE   Y A + EDA I
Sbjct: 507  TSSYAVTVQAQDGAPSSLRSDGLPNMYQKKFKVEVLDQNDNPPRFEQPTYNAEIAEDADI 566

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
             + V+ V+A D D    A I Y ++         + D  F++  ++G I  N  LD E +
Sbjct: 567  NSKVIEVTARDKD--DFAVIRYDITD-------GNVDNAFMVEEKSGVIRVNNQLDYEKI 617

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL---YTANIMEDALVGTSVS 601
            + Y L V A DG     SD   V +S+ +VNDN P+F+         NI+E+      ++
Sbjct: 618  TDYYLRVRASDG---IHSDEATVHVSISNVNDNPPIFENMQNPHVVRNIIEEEKRPDPIA 674

Query: 602  QVGATDAD---VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD---L 655
            ++   D D    G N  I + LD   +    F I P  G +  +K +DR+    +    +
Sbjct: 675  KITVRDPDWDKGGKNPYITFSLDRTGQYAKHFRITP-EGELFLDKGIDRDPPNGYPQARV 733

Query: 656  KAVAIDGGTP---PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
              +A D   P    QS+T++V I ++DIND+ P    +    +     P+   I  + A 
Sbjct: 734  NIIAEDRLEPNGKVQSNTLVVEIHLDDINDNAPFLNMEQPVVFNENQKPM--LITNLTAD 791

Query: 713  DPDE---GPNAVVHYSIKGGDDS---NSFSLETRQGSDKAELVTMVDLDYESPRKKYELV 766
            D D+   G        I    +     SF++  +  S   +L + V  D E  RK Y + 
Sbjct: 792  DNDDESVGNGPPFQMRIDPNAEPIILTSFAV-NKAPSGVWQLHSNVMFDREE-RKVYNIP 849

Query: 767  I----RAASPPLWNDV---RVEILVTDVNDNAPVMKDFQ--IIFNNYKDCFPVGPFGRVP 817
            I         P         +E+++ D NDN   MKD +  I   NYK+  P    GR  
Sbjct: 850  IVISDNGGGDPSRRQTGTSTLEVVIGDENDND--MKDGKSAITVYNYKNSLPDTMIGRAY 907

Query: 818  AYDADVTDKLQYRILSGNNANLILLN-ETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEI 876
              D D  D         +       +    G +T+         +L    + V D     
Sbjct: 908  VDDPDDWDLPDKEFTWFDTIQPTYFSLHPKGMITMKAGTPAGEYRL---RIKVYDQKWNS 964

Query: 877  KAMMQLSVRL--ITEEMLLNSITVRLNDMTAEQFLSPLLG-----FFIDGLAAIIPCPKE 929
            +A  ++ V    I EE +  S +VRL+ +T   F++P  G        D +A  +  P  
Sbjct: 965  QATAEVIVNSIEIPEEAVKKSGSVRLDGVTEVDFITPRGGESMREMLRDAVAKYLSVPLG 1024

Query: 930  NIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARL 989
            N+ +F+V+    V   I++  FS              SP++ P  +   +    T L   
Sbjct: 1025 NVDLFTVR---GVNKTIVDARFSVHN-----------SPYWDPVKINGLLGEKSTELKDT 1070

Query: 990  ATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEG 1049
               ++L    + C+ EP      C + L   +   F+  ++  F  +     + C C  G
Sbjct: 1071 LKAEILGIGIDECMKEPGPCDGPCTSFLTILDTPYFIYGNTSSFVGVNAYADYDCACRIG 1130

Query: 1050 FTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCELRARS 1109
               +N      +  CE       C +G  C+       L   C     +    CE    S
Sbjct: 1131 -PVLNSPRGPIRDQCE-----EYCFNGGTCILNG----LFPRCECPDNFEGPRCEALEAS 1180

Query: 1110 FPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRGGG 1169
            F   SF   P L       +  +F + T +GL+ YNG ++   D    + V+ E    G 
Sbjct: 1181 FNGVSFGWLPSLPACSDGSITFEFTSHTENGLMFYNGPHSIPSDKSITDFVAVELD-DGI 1239

Query: 1170 PGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNR-TITMILDDC 1215
            P    +   G  K ++    N GD   H +E+ + +R  + + LD C
Sbjct: 1240 PVAYINLGSGIRKLQLNDNKNYGDKESHLLELRWNDRQEVRLTLDGC 1286



 Score =  210 bits (513), Expect = 4e-52
 Identities = 195/746 (26%), Positives = 342/746 (45%), Gaps = 81/746 (10%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + + D ND++P+F+   Y  ++ + +    TV+ + ATD D G+NA + Y++        
Sbjct: 209 VTITDKNDNAPIFDKNDYRETIPQDSKVNQTVMRVAATDIDEGENARITYSLR------A 262

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKV-ARYTVLVKATDQASPVSDR 129
           N +++            D F+ID +SG +    +++ EKV  ++ ++  A D  +P ++ 
Sbjct: 263 NRDESDL----------DYFQIDPQSGFIKLVKAIEAEKVDYQFELVAAARDGGTPSNE- 311

Query: 130 LSSTATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             +TA +++ ++  N   P+F+E   + + ++E  +    P++     ++ +      + 
Sbjct: 312 --TTAQVNIKVVSSNRRAPEFTEVPDHIIDIEESFNDFGRPIVTLRAVSNIE---KPVVY 366

Query: 189 YAIIGGNTQMQFS------IDSLSG--DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240
           ++++ G T+          ++  +G  D+ L + LDYE V +Y+L IR Q+    S    
Sbjct: 367 FSLVNGQTEDTNKEETFRLVERANGTMDIFLARKLDYETVSNYQLNIRVQNDFDVSAETI 426

Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDK 299
            +L   + D ND  P F   +   SV EN  +   ++R++A D D    N ++TY +   
Sbjct: 427 VRL--RVLDSNDEIPSF-IDIESGSVLENSAVQTFVLRIRAIDKDGTSPNNKVTYRL--- 480

Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-------PRSATATX 352
               N D   +ID  +G + T  +LDRE  + Y + V A DG          P       
Sbjct: 481 --LSNTD-TFSIDSETGEIRTLKRLDREETSSYAVTVQAQDGAPSSLRSDGLPNMYQKKF 537

Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRF 412
                        F    Y  E+AED    + V+ +TA D D+   + Y+IT GN    F
Sbjct: 538 KVEVLDQNDNPPRFEQPTYNAEIAEDADINSKVIEVTARDKDDFAVIRYDITDGNVDNAF 597

Query: 413 SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENA 472
            +  ++  G+I V   LD+++   Y L V A+D G  SD A V ++I++ N+  P+FEN 
Sbjct: 598 MVEEKS--GVIRVNNQLDYEKITDYYLRVRASD-GIHSDEATVHVSISNVNDNPPIFENM 654

Query: 473 --PYTA-SVFEDAPIGTTVLVVSATDSD---VGINAQITYSLSSEISNEAVAHHDQQFVI 526
             P+   ++ E+      +  ++  D D    G N  IT+SL      +    + + F I
Sbjct: 655 QNPHVVRNIIEEEKRPDPIAKITVRDPDWDKGGKNPYITFSL------DRTGQYAKHFRI 708

Query: 527 NPQTGAITTNKLLDRETMSGY---LLTVTARDGGVPS---LSDTTDVEISVVDVNDNEPV 580
            P+ G +  +K +DR+  +GY    + + A D   P+    S+T  VEI + D+NDN P 
Sbjct: 709 TPE-GELFLDKGIDRDPPNGYPQARVNIIAEDRLEPNGKVQSNTLVVEIHLDDINDNAPF 767

Query: 581 FK-QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE--EGSFVIDPA-S 636
              +Q    N  +  ++ T+++     D  VG        +DP        SF ++ A S
Sbjct: 768 LNMEQPVVFNENQKPMLITNLTADDNDDESVGNGPPFQMRIDPNAEPIILTSFAVNKAPS 827

Query: 637 GV--IRTNKALDRESVATHDLKAVAID--GGTPP--QSSTVIVHIKIEDINDSPPVFESD 690
           GV  + +N   DRE    +++  V  D  GG P   Q+ T  + + I D ND+       
Sbjct: 828 GVWQLHSNVMFDREERKVYNIPIVISDNGGGDPSRRQTGTSTLEVVIGDENDNDMKDGKS 887

Query: 691 CLTFYISENSPIGTTIGEIRAHDPDE 716
            +T Y  +NS   T IG     DPD+
Sbjct: 888 AITVYNYKNSLPDTMIGRAYVDDPDD 913



 Score =  143 bits (346), Expect = 7e-32
 Identities = 149/499 (29%), Positives = 222/499 (44%), Gaps = 43/499 (8%)

Query: 398 RLHYEITGGNTRGRFS---ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM 454
           R H+E+       +F    +  Q GR    ++ P    Q+++ V + S         +  
Sbjct: 40  RSHFEVESIGEHLKFEKHHVRRQAGRQPYRLSDPQ--LQKQKMVNSESPEARAASMPSRG 97

Query: 455 VQINITDAN-NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513
           V  N T A  N  P F     T S+ E    GT V  V A D D G   ++ Y +    S
Sbjct: 98  VTPNPTAAAINTRPTFIKCNET-SIPEGENAGTFVTKVEAYDPDQGPAGKVRYEIIRSQS 156

Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL---TVTARDGGVPSLSDTTDVEIS 570
            E      +QF +N  TG ITT K+ DR+      L   TV A D G P+L       ++
Sbjct: 157 AE------KQFNVNSYTGEITTAKVFDRDEPKREKLLYVTVKAVDEGFPALDVLCTFSVT 210

Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS- 629
           + D NDN P+F +  Y   I +D+ V  +V +V ATD D G N RI Y L   +R+E   
Sbjct: 211 ITDKNDNAPIFDKNDYRETIPQDSKVNQTVMRVAATDIDEGENARITYSL-RANRDESDL 269

Query: 630 --FVIDPASGVIRTNKALDRESV-ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686
             F IDP SG I+  KA++ E V    +L A A DGGTP   +T  V+IK+   N   P 
Sbjct: 270 DYFQIDPQSGFIKLVKAIEAEKVDYQFELVAAARDGGTPSNETTAQVNIKVVSSNRRAPE 329

Query: 687 FES--DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD 744
           F    D +       +  G  I  +RA    E P  VV++S+  G   ++   ET +  +
Sbjct: 330 FTEVPDHIIDIEESFNDFGRPIVTLRAVSNIEKP--VVYFSLVNGQTEDTNKEETFRLVE 387

Query: 745 KA----ELVTMVDLDYESPRKKYELVIRAASP-PLWNDVRVEILVTDVNDNAPVMKDFQ- 798
           +A    ++     LDYE+    Y+L IR  +   +  +  V + V D ND  P   D + 
Sbjct: 388 RANGTMDIFLARKLDYETV-SNYQLNIRVQNDFDVSAETIVRLRVLDSNDEIPSFIDIES 446

Query: 799 --IIFNNYKDCFPVGPFGRVPAYDADVT---DKLQYRILSGNNANLILLNETTGSMTLSP 853
             ++ N+    F +    R+ A D D T   +K+ YR+LS  N +   ++  TG +    
Sbjct: 447 GSVLENSAVQTFVL----RIRAIDKDGTSPNNKVTYRLLS--NTDTFSIDSETGEIRTLK 500

Query: 854 QLNTNVPKLATMEVSVTDG 872
           +L+        + V   DG
Sbjct: 501 RLDREETSSYAVTVQAQDG 519


>UniRef50_UPI00006A1011 Cluster: FAT tumor suppressor homolog 3;
           n=1; Xenopus tropicalis|Rep: FAT tumor suppressor
           homolog 3 - Xenopus tropicalis
          Length = 978

 Score =  239 bits (584), Expect = 1e-60
 Identities = 175/533 (32%), Positives = 262/533 (49%), Gaps = 27/533 (5%)

Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYA 466
           G F++   +G  +I + QPLD + +  Y +TV A+D       S  A V I + D N+  
Sbjct: 17  GHFAVDMSSG--IIILEQPLDRELQSSYNITVKASDLSPVLTLSSLAFVTITVLDVNDNP 74

Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
           P+FE   Y  +V ED  +GT VL V A   D+G NA+I YS+ S   NE       QF I
Sbjct: 75  PIFERRDYWVTVAEDTTLGTKVLSVFAASKDIGTNAEILYSIRS--GNEHA-----QFFI 127

Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586
           NP+TGAI+    LD E    + L V A DGG PSLS  T V I++ DVNDN PVF Q++Y
Sbjct: 128 NPKTGAISVVNTLDYENCKHFYLVVEATDGGSPSLSAVTTVNINLTDVNDNAPVFSQEVY 187

Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646
           +A I EDA VG SV  V  T +    NG  ++  +            PA G  R   A  
Sbjct: 188 SAVISEDASVGDSVVMVSVTSSI--SNGLFYFAAN--FNHFFLLFTTPAEG--RQRGASA 241

Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706
           R  V+ + L   A D G P  SSTV V+I I D+ND+ P F     +  I EN P+GT+I
Sbjct: 242 RWKVSGYSLLVQARDSGAPALSSTVTVNIDISDVNDNSPQFTPANYSAVIQENKPVGTSI 301

Query: 707 GEIRAHDPDEGPNA-VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765
            ++   D D   N     ++I  G++   F L+ + G  ++ +V    +  E        
Sbjct: 302 VQLVVTDKDSFHNGPPFEFTIISGNEGGEFLLD-QSGVLRSAVVFQHTISDE--HLLCVQ 358

Query: 766 VIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD 825
           V  +  P L +   + I V + + + P     ++     +D FP G  G++ A D D+ D
Sbjct: 359 VKDSGKPALTSQSFLHIRVIEESVHKPSAIPLEVYIVTMEDDFPGGVIGKIHATDQDIYD 418

Query: 826 KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVR 885
            L Y  L     +L  +N   G +     L+       T+ VSV DG  ++   + + V 
Sbjct: 419 VLSYN-LKSEQKSLFKVNNHDGKLIALGGLDGG---KYTLNVSVNDGRYQVSIDVTVHVE 474

Query: 886 LITEEMLLNSITVRLNDMTAEQFLS-PLLGFFIDGLAAIIPCPKENIYIFSVQ 937
            + +EML N++T+R  +++ E F+   + GF      A++   ++++YI S+Q
Sbjct: 475 QLRQEMLQNAVTIRFENISPEDFVGLHMHGFRRTLRNAVLTQKEDSLYIISIQ 527



 Score =  186 bits (453), Expect = 8e-45
 Identities = 138/443 (31%), Positives = 209/443 (47%), Gaps = 26/443 (5%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F +D  SG ++    LDRE  + Y + VKA+D  SPV   LSS A + + ++D NDN P 
Sbjct: 19  FAVDMSSGIIILEQPLDRELQSSYNITVKASD-LSPVLT-LSSLAFVTITVLDVNDNPPI 76

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209
           F  + Y V+V ED ++     +  + A   D+G N+ I Y+I  GN   QF I+  +G +
Sbjct: 77  FERRDYWVTVAEDTTLGTK--VLSVFAASKDIGTNAEILYSIRSGNEHAQFFINPKTGAI 134

Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269
           S+V TLDYE  + + LV+ A DGGSPS S  T + IN+ DVNDNAP F   ++   +SE+
Sbjct: 135 SVVNTLDYENCKHFYLVVEATDGGSPSLSAVTTVNINLTDVNDNAPVFSQEVYSAVISED 194

Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329
             +G S+V V        ++  L Y   + ++       +   P  G     G   R   
Sbjct: 195 ASVGDSVVMV---SVTSSISNGLFYFAANFNHF----FLLFTTPAEG--RQRGASARWKV 245

Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389
           + Y LLV A D G P  S+T T              F P  Y   + E++P GT +V L 
Sbjct: 246 SGYSLLVQARDSGAPALSSTVTVNIDISDVNDNSPQFTPANYSAVIQENKPVGTSIVQLV 305

Query: 390 ATDADEDNR---LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446
            TD D  +      + I  GN  G F +      G++  A          ++L V   DS
Sbjct: 306 VTDKDSFHNGPPFEFTIISGNEGGEFLLDQS---GVLRSAVVFQHTISDEHLLCVQVKDS 362

Query: 447 G--GRSDTAMVQINITDANNYAP-VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503
           G    +  + + I + + + + P       Y  ++ +D P G  +  + ATD D  I   
Sbjct: 363 GKPALTSQSFLHIRVIEESVHKPSAIPLEVYIVTMEDDFP-GGVIGKIHATDQD--IYDV 419

Query: 504 ITYSLSSE-ISNEAVAHHDQQFV 525
           ++Y+L SE  S   V +HD + +
Sbjct: 420 LSYNLKSEQKSLFKVNNHDGKLI 442



 Score =  153 bits (372), Expect = 5e-35
 Identities = 136/500 (27%), Positives = 227/500 (45%), Gaps = 32/500 (6%)

Query: 182 GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP--SRSN 239
           G N  + Y+++  +    F++D  SG + L + LD E   SY + ++A D  SP  + S+
Sbjct: 2   GINRKVVYSLVD-SADGHFAVDMSSGIIILEQPLDRELQSSYNITVKASDL-SPVLTLSS 59

Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
              + I + DVNDN P F    +  +V+E+  +G  ++ V A   D G NAE+ Y++   
Sbjct: 60  LAFVTITVLDVNDNPPIFERRDYWVTVAEDTTLGTKVLSVFAASKDIGTNAEILYSIR-- 117

Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
             +GN      I+P++G +     LD E    + L+V ATDGG P  SA  T        
Sbjct: 118 --SGNEHAQFFINPKTGAISVVNTLDYENCKHFYLVVEATDGGSPSLSAVTTVNINLTDV 175

Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG 419
                 F    Y   ++ED   G  VV ++ T +   N L Y     N       T   G
Sbjct: 176 NDNAPVFSQEVYSAVISEDASVGDSVVMVSVT-SSISNGLFYFAANFNHFFLLFTTPAEG 234

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477
           R     A+     +   Y L V A DSG    S T  V I+I+D N+ +P F  A Y+A 
Sbjct: 235 RQRGASAR----WKVSGYSLLVQARDSGAPALSSTVTVNIDISDVNDNSPQFTPANYSAV 290

Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
           + E+ P+GT+++ +  TD D   N    +  +    NE       +F+++ Q+G + +  
Sbjct: 291 IQENKPVGTSIVQLVVTDKDSFHNGP-PFEFTIISGNEG-----GEFLLD-QSGVLRSAV 343

Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP-VFKQQLYTANIMEDALV 596
           +        +LL V  +D G P+L+  + + I V++ + ++P     ++Y    MED   
Sbjct: 344 VFQHTISDEHLLCVQVKDSGKPALTSQSFLHIRVIEESVHKPSAIPLEVYIVT-MEDDFP 402

Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
           G  + ++ ATD D+     + Y L  K  ++  F ++   G +     LD      +   
Sbjct: 403 GGVIGKIHATDQDI--YDVLSYNL--KSEQKSLFKVNNHDGKLIALGGLDGGKYTLN--- 455

Query: 657 AVAIDGGTPPQSSTVIVHIK 676
            V+++ G    S  V VH++
Sbjct: 456 -VSVNDGRYQVSIDVTVHVE 474



 Score =  147 bits (357), Expect = 3e-33
 Identities = 123/436 (28%), Positives = 207/436 (47%), Gaps = 41/436 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I VLD ND+ P+FE + Y  +V E  + GT VL++ A  +DIG NAE+ Y+I        
Sbjct: 65  ITVLDVNDNPPIFERRDYWVTVAEDTTLGTKVLSVFAASKDIGTNAEILYSIR------S 118

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             E A              F I+ ++GA+    +LD E    + ++V+ATD  SP    L
Sbjct: 119 GNEHAQ-------------FFINPKTGAISVVNTLDYENCKHFYLVVEATDGGSP---SL 162

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           S+  T+++N+ D NDN P FS++ Y+  + ED SV D+ V+  + ++     +N    +A
Sbjct: 163 SAVTTVNINLTDVNDNAPVFSQEVYSAVISEDASVGDSVVMVSVTSSI----SNGLFYFA 218

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
               N    F + +   +          +V  Y L+++A+D G+P+ S+T  + I+I DV
Sbjct: 219 ---ANFNHFFLLFTTPAEGRQRGASARWKVSGYSLLVQARDSGAPALSSTVTVNIDISDV 275

Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA-ELTYTMTDKDYTGNVDLPI 309
           NDN+P+F  + +   + EN P+G SIV++   D D   N     +T+     +GN     
Sbjct: 276 NDNSPQFTPANYSAVIQENKPVGTSIVQLVVTDKDSFHNGPPFEFTI----ISGNEGGEF 331

Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            +D +SG + ++         ++ L V   D G P  ++ +                +P 
Sbjct: 332 LLD-QSGVLRSAVVFQHTISDEHLLCVQVKDSGKPALTSQSFLHIRVIEESVHKPSAIPL 390

Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
           +  +   ED+ PG  +  + ATD D  + L Y +     +  F + + +G+ LI +   L
Sbjct: 391 EVYIVTMEDDFPGGVIGKIHATDQDIYDVLSYNLK-SEQKSLFKVNNHDGK-LIALG-GL 447

Query: 430 DFKQERRYVLTVSATD 445
           D     +Y L VS  D
Sbjct: 448 D---GGKYTLNVSVND 460



 Score = 70.9 bits (166), Expect = 5e-10
 Identities = 64/242 (26%), Positives = 115/242 (47%), Gaps = 19/242 (7%)

Query: 102 RASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE 161
           R +  R KV+ Y++LV+A D  +P    LSST T++++I D NDN PQF+   Y+  + E
Sbjct: 237 RGASARWKVSGYSLLVQARDSGAPA---LSSTVTVNIDISDVNDNSPQFTPANYSAVIQE 293

Query: 162 DISVTDNPVIAKIKATDADVGANS-AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV 220
           +  V  +  I ++  TD D   N     + II GN   +F +D  SG +       +   
Sbjct: 294 NKPVGTS--IVQLVVTDKDSFHNGPPFEFTIISGNEGGEFLLDQ-SGVLRSAVVFQHTIS 350

Query: 221 RSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP-RFYTSLFQESVSENVPIGYSIVRV 279
             + L ++ +D G P+ ++ + L I + + + + P      ++  ++ ++ P G  I ++
Sbjct: 351 DEHLLCVQVKDSGKPALTSQSFLHIRVIEESVHKPSAIPLEVYIVTMEDDFP-GGVIGKI 409

Query: 280 QAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTAT 339
            A D D  +   L+Y +  +  +        ++   G +   G LD     KY L V+  
Sbjct: 410 HATDQD--IYDVLSYNLKSEQKS-----LFKVNNHDGKLIALGGLD---GGKYTLNVSVN 459

Query: 340 DG 341
           DG
Sbjct: 460 DG 461



 Score = 39.1 bits (87), Expect = 1.7
 Identities = 12/39 (30%), Positives = 21/39 (53%)

Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348
            C E  + C    C NG  C +++ ++ C+C  G+ G+ C
Sbjct: 754  CEEDINECEREDCENGGTCVNVFGSFFCNCSHGYVGQYC 792


>UniRef50_Q4RKB4 Cluster: Chromosome 18 SCAF15030, whole genome
           shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 18
           SCAF15030, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1521

 Score =  239 bits (584), Expect = 1e-60
 Identities = 194/623 (31%), Positives = 284/623 (45%), Gaps = 54/623 (8%)

Query: 99  LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158
           L+ + +LDRE+   Y ++++  D  +P     SS A + V+I D NDN PQF   TY   
Sbjct: 358 LIVKGTLDREQKDSYELILRVRDGGNPPR---SSQALLRVSITDVNDNSPQFERSTYEAE 414

Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ---FSIDSLSGDVSLVKTL 215
           + E+ +    PV+ +++A+D DVG N  + Y + G  T+       +D  +G +S++  +
Sbjct: 415 MAEN-APPGTPVL-QVRASDRDVGVNGQVEY-VFGAATESVRRLLRLDEATGWLSVLHRI 471

Query: 216 DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP--------RFYTSLFQESVS 267
           D E+V   R  + A+D G P R++ T +++ +RD NDN P        R         V 
Sbjct: 472 DREEVAQLRFTVTARDRGQPPRTDRTTVVLAVRDENDNVPVVEIRKIGRIPVRDGAALVP 531

Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMT-DKDYT----GNVDLP-------ITIDPRS 315
           ENV +   +  VQ  D D+G N  +T T+  D  +T    G   LP          + + 
Sbjct: 532 ENVLVDTPVALVQVSDRDQGENGAVTCTVVGDVPFTLKPAGETVLPPLPAEDAFDRNKKK 591

Query: 316 GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375
            +++TS  LD ET  +Y + + A D G P  S+ ++              F     EV  
Sbjct: 592 YFLHTSALLDYETTKEYSVTIVAVDSGSPSLSSNSSLMVRVVDINDHPPIFAQSVVEVHF 651

Query: 376 AEDEPPGTPVVTLTATDADEDNRLHYEIT---GGNTRGRFSITSQNGRGLITVAQPLDFK 432
           AE+  PG  VVT+ ATDAD         +    GN  G F I + NG   I     LD +
Sbjct: 652 AENNSPGERVVTVVATDADSGKNAEIAFSLDPAGN--GPFYIDADNGD--IRATGVLDRE 707

Query: 433 QERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
           Q  RY L V A D G  S   +A V I +TD N+ AP F    +T  V E+    + V +
Sbjct: 708 QRERYELRVIAKDKGTPSLQGSATVVIQVTDRNDNAPKFAQEIFTFYVKENLLANSPVGM 767

Query: 491 VSATDSDVGINAQITY-----------SLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           V+ TD+D G NA+++             + S    +A    ++ F I   TG I ++   
Sbjct: 768 VTVTDADEGENAELSLFVEIGGPEERKMVGSTEDEDAEKGQEEMFSIENNTGTIFSSASF 827

Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF---KQQLYTANIMEDALV 596
           DRE +S Y   V A DGG P  + T  V + V D NDN P       + YT  +   +  
Sbjct: 828 DREKLSIYTFRVRAVDGGEPRKTATATVSLFVTDENDNAPSITSPANESYTL-LPPASSA 886

Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
            T V  V A D+D GLN  + Y L         F I   +GVI   + L+R     H L 
Sbjct: 887 RTVVRTVKAVDSDSGLNADLRYAL-VGGNPYRLFEIGHTNGVITLAEPLERRHRGLHRLV 945

Query: 657 AVAIDGGTPPQSSTVIVHIKIED 679
               D G P   +T +VHI I D
Sbjct: 946 VRVTDSGIPSLCATALVHIFIND 968



 Score =  229 bits (560), Expect = 8e-58
 Identities = 189/643 (29%), Positives = 281/643 (43%), Gaps = 51/643 (7%)

Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332
           G  I RV+A     G N E     +        D+P     +   +   G LDRE +  Y
Sbjct: 315 GSPITRVEALGDRRGRNGENGGARSTVFKLQVADIPD--GEKQPQLIVKGTLDREQKDSY 372

Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392
           +L++   DGG+PPRS+ A               F    YE E+AE+ PPGTPV+ + A+D
Sbjct: 373 ELILRVRDGGNPPRSSQALLRVSITDVNDNSPQFERSTYEAEMAENAPPGTPVLQVRASD 432

Query: 393 ADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG-- 448
            D   + ++ Y         R  +      G ++V   +D ++  +   TV+A D G   
Sbjct: 433 RDVGVNGQVEYVFGAATESVRRLLRLDEATGWLSVLHRIDREEVAQLRFTVTARDRGQPP 492

Query: 449 RSDTAMVQINITDANNYAPVFE-----NAPY---TASVFEDAPIGTTVLVVSATDSDVGI 500
           R+D   V + + D N+  PV E       P     A V E+  + T V +V  +D D G 
Sbjct: 493 RTDRTTVVLAVRDENDNVPVVEIRKIGRIPVRDGAALVPENVLVDTPVALVQVSDRDQGE 552

Query: 501 NAQITYSLSSEI------SNEAVAHH---DQQFVINPQTGAITTNKLLDRETMSGYLLTV 551
           N  +T ++  ++      + E V      +  F  N +   + T+ LLD ET   Y +T+
Sbjct: 553 NGAVTCTVVGDVPFTLKPAGETVLPPLPAEDAFDRNKKKYFLHTSALLDYETTKEYSVTI 612

Query: 552 TARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG 611
            A D G PSLS  + + + VVD+ND+ P+F Q +   +  E+   G  V  V ATDAD G
Sbjct: 613 VAVDSGSPSLSSNSSLMVRVVDINDHPPIFAQSVVEVHFAENNSPGERVVTVVATDADSG 672

Query: 612 LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671
            N  I + LDP     G F ID  +G IR    LDRE    ++L+ +A D GTP    + 
Sbjct: 673 KNAEIAFSLDPAG--NGPFYIDADNGDIRATGVLDREQRERYELRVIAKDKGTPSLQGSA 730

Query: 672 IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK-GGD 730
            V I++ D ND+ P F  +  TFY+ EN    + +G +   D DEG NA +   ++ GG 
Sbjct: 731 TVVIQVTDRNDNAPKFAQEIFTFYVKENLLANSPVGMVTVTDADEGENAELSLFVEIGGP 790

Query: 731 DSNSFSLETRQGSDKAELVTMVDLDYES---------PRKK---YELVIRA---ASPPLW 775
           +       T     +     M  ++  +          R+K   Y   +RA     P   
Sbjct: 791 EERKMVGSTEDEDAEKGQEEMFSIENNTGTIFSSASFDREKLSIYTFRVRAVDGGEPRKT 850

Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR-----VPAYDAD--VTDKLQ 828
               V + VTD NDNAP +       N      P     R     V A D+D  +   L+
Sbjct: 851 ATATVSLFVTDENDNAPSITS---PANESYTLLPPASSARTVVRTVKAVDSDSGLNADLR 907

Query: 829 YRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
           Y ++ GN   L  +  T G +TL+  L      L  + V VTD
Sbjct: 908 YALVGGNPYRLFEIGHTNGVITLAEPLERRHRGLHRLVVRVTD 950



 Score =  205 bits (500), Expect = 2e-50
 Identities = 192/649 (29%), Positives = 290/649 (44%), Gaps = 85/649 (13%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++++ D ND+SP FE   YEA + E A  GT VL ++A+D+D+G N +VEY     T   
Sbjct: 393  RVSITDVNDNSPQFERSTYEAEMAENAPPGTPVLQVRASDRDVGVNGQVEYVFGAATES- 451

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                            V+ + R+D  +G L     +DRE+VA+    V A D+  P   R
Sbjct: 452  ----------------VRRLLRLDEATGWLSVLHRIDREEVAQLRFTVTARDRGQP--PR 493

Query: 130  LSSTATIHVNIIDDNDNYP--------QFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181
               T T+ + + D+NDN P        +   +     V E++ V D PV A ++ +D D 
Sbjct: 494  TDRT-TVVLAVRDENDNVPVVEIRKIGRIPVRDGAALVPENVLV-DTPV-ALVQVSDRDQ 550

Query: 182  GANSAIRYAIIG---------GNTQMQ-------FSIDSLSGDVSLVKTLDYEQVRSYRL 225
            G N A+   ++G         G T +        F  +     +     LDYE  + Y +
Sbjct: 551  GENGAVTCTVVGDVPFTLKPAGETVLPPLPAEDAFDRNKKKYFLHTSALLDYETTKEYSV 610

Query: 226  VIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD 285
             I A D GSPS S+ + L++ + D+ND+ P F  S+ +   +EN   G  +V V A DAD
Sbjct: 611  TIVAVDSGSPSLSSNSSLMVRVVDINDHPPIFAQSVVEVHFAENNSPGERVVTVVATDAD 670

Query: 286  EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP 345
             G NAE+ +++   D  GN   P  ID  +G +  +G LDRE + +Y+L V A D G P 
Sbjct: 671  SGKNAEIAFSL---DPAGNG--PFYIDADNGDIRATGVLDREQRERYELRVIAKDKGTPS 725

Query: 346  RSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR----LHY 401
               +AT              F    +   + E+    +PV  +T TDADE       L  
Sbjct: 726  LQGSATVVIQVTDRNDNAPKFAQEIFTFYVKENLLANSPVGMVTVTDADEGENAELSLFV 785

Query: 402  EITG-------GNT------RGRFSITS-QNGRGLITVAQPLDFKQERRYVLTVSATDSG 447
            EI G       G+T      +G+  + S +N  G I  +   D ++   Y   V A D G
Sbjct: 786  EIGGPEERKMVGSTEDEDAEKGQEEMFSIENNTGTIFSSASFDREKLSIYTFRVRAVDGG 845

Query: 448  --GRSDTAMVQINITDANNYAP-VFENAPYTASVFEDAPIGTTVL-VVSATDSDVGINAQ 503
               ++ TA V + +TD N+ AP +   A  + ++   A    TV+  V A DSD G+NA 
Sbjct: 846  EPRKTATATVSLFVTDENDNAPSITSPANESYTLLPPASSARTVVRTVKAVDSDSGLNAD 905

Query: 504  ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD 563
            + Y+L          +  + F I    G IT  + L+R     + L V   D G+PSL  
Sbjct: 906  LRYALVG-------GNPYRLFEIGHTNGVITLAEPLERRHRGLHRLVVRVTDSGIPSLCA 958

Query: 564  TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612
            T  V I +     N+ +    L  A I        S+   G  D+D  L
Sbjct: 959  TALVHIFI-----NDSLANASLVEAQIARSLAAPLSLDIAGDPDSDRSL 1002



 Score =  156 bits (379), Expect = 7e-36
 Identities = 113/391 (28%), Positives = 183/391 (46%), Gaps = 37/391 (9%)

Query: 429 LDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
           LD++  + Y +T+ A DSG  S    + + + + D N++ P+F  +       E+   G 
Sbjct: 600 LDYETTKEYSVTIVAVDSGSPSLSSNSSLMVRVVDINDHPPIFAQSVVEVHFAENNSPGE 659

Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
            V+ V ATD+D G NA+I +SL    +          F I+   G I    +LDRE    
Sbjct: 660 RVVTVVATDADSGKNAEIAFSLDPAGNGP--------FYIDADNGDIRATGVLDREQRER 711

Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
           Y L V A+D G PSL  +  V I V D NDN P F Q+++T  + E+ L  + V  V  T
Sbjct: 712 YELRVIAKDKGTPSLQGSATVVIQVTDRNDNAPKFAQEIFTFYVKENLLANSPVGMVTVT 771

Query: 607 DADVGLNGRIHYELD---PKDR--------------EEGSFVIDPASGVIRTNKALDRES 649
           DAD G N  +   ++   P++R              +E  F I+  +G I ++ + DRE 
Sbjct: 772 DADEGENAELSLFVEIGGPEERKMVGSTEDEDAEKGQEEMFSIENNTGTIFSSASFDREK 831

Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY--ISENSPIGTTIG 707
           ++ +  +  A+DGG P +++T  V + + D ND+ P   S     Y  +   S   T + 
Sbjct: 832 LSIYTFRVRAVDGGEPRKTATATVSLFVTDENDNAPSITSPANESYTLLPPASSARTVVR 891

Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
            ++A D D G NA + Y++ GG+    F +    G     ++T+ +      R  + LV+
Sbjct: 892 TVKAVDSDSGLNADLRYALVGGNPYRLFEIGHTNG-----VITLAEPLERRHRGLHRLVV 946

Query: 768 RAAS---PPLWNDVRVEILVTDVNDNAPVMK 795
           R      P L     V I + D   NA +++
Sbjct: 947 RVTDSGIPSLCATALVHIFINDSLANASLVE 977


>UniRef50_UPI00006A0F39 Cluster: Protocadherin alpha 13 precursor
           (PCDH-alpha13).; n=6; Xenopus tropicalis|Rep:
           Protocadherin alpha 13 precursor (PCDH-alpha13). -
           Xenopus tropicalis
          Length = 779

 Score =  238 bits (583), Expect = 1e-60
 Identities = 175/608 (28%), Positives = 291/608 (47%), Gaps = 34/608 (5%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F ++  +G L     +DRE V   T +   + +A  V +   +   + + I D NDN P 
Sbjct: 85  FNVNLENGNLYVADRIDRESVCEMTPICSLSLEA--VVENPLNIFHVEIEIKDINDNSPS 142

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG-- 207
           FS+ T  + + E        ++    A D D G NS   Y I   N   + ++ + S   
Sbjct: 143 FSKDTMNLEITELTHPGTRFILGD--ALDPDDGMNSLQAYDI-SKNEYFKLNVKTSSDGR 199

Query: 208 ---DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
              ++ L + LD E+  + ++++ A DGG P+R+  + + I I D+NDN+P F   L+Q 
Sbjct: 200 MIPELVLERPLDREKQSALQIILTALDGGIPARTGISMIKIIISDINDNSPLFSQELYQV 259

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
           S++E+ P+   ++++ A DADEGVN  +TY ++    +       TID  +G + T G L
Sbjct: 260 SLTESAPVNTLVIQMNATDADEGVNGHITYYLS--RISKAAQQKFTIDTETGEIRTKGTL 317

Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
           D ET   Y+++V A DGG     + A                +       + E+  PGT 
Sbjct: 318 DFETTKAYEMIVEAQDGGG--LFSNAKVVIQIVDANDNAPEIILTSVSNSIPENSVPGTV 375

Query: 385 VVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGL-ITVAQPLDFKQERRYVLTV 441
           +  +   D D  E+  ++ +IT       F ITS +     +   + LD ++   Y +T+
Sbjct: 376 IALINIRDIDSGENGNVYCQIT---DLLPFEITSSSSNYFRLLTTRNLDREEMHEYNITI 432

Query: 442 SATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499
            ATD G    S T  +++ + D N+  PVF  A Y   + E+ P G++V  V A+D D+ 
Sbjct: 433 KATDRGSPSLSTTKTIKLVLLDVNDNPPVFGQASYVVYIPENNPSGSSVFQVQASDPDLD 492

Query: 500 INAQITYS-LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558
            NA+ITYS +++   N  V+ +     IN  TG +   +  D E +  + + V A+D G 
Sbjct: 493 DNAKITYSIMNTNTDNFPVSSY---ISINSMTGILYAQRPFDYEQLREFGIQVMAKDNGS 549

Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQQLYTAN-------IMEDALVGTSVSQVGATDADVG 611
           P L+ TT V I + D+NDN P       +A+       +   +  G  V++V A DAD G
Sbjct: 550 PPLNSTTTVTICITDLNDNSPKILYPSTSADDSAQFEIVPRTSNKGELVAKVVAVDADSG 609

Query: 612 LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671
            N  + YE   +  E  SF I   +G IRT +    +      L  +  D G+PP+S+T+
Sbjct: 610 HNAWLSYEF-LQVSESMSFTISRHTGEIRTLRVFPEKETLKQRLVVLVKDNGSPPRSATI 668

Query: 672 IVHIKIED 679
            +++ + D
Sbjct: 669 NLNLVVAD 676



 Score =  223 bits (546), Expect = 4e-56
 Identities = 167/604 (27%), Positives = 285/604 (47%), Gaps = 29/604 (4%)

Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ-DGGSPSRSNTTQLLINIRDVNDNAPRFY 258
           F+++  +G++ +   +D E V     +     +    +  N   + I I+D+NDN+P F 
Sbjct: 85  FNVNLENGNLYVADRIDRESVCEMTPICSLSLEAVVENPLNIFHVEIEIKDINDNSPSFS 144

Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS-GW 317
                  ++E    G   +   A D D+G+N+   Y ++  +Y   +++  + D R    
Sbjct: 145 KDTMNLEITELTHPGTRFILGDALDPDDGMNSLQAYDISKNEYF-KLNVKTSSDGRMIPE 203

Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377
           +     LDRE Q+  Q+++TA DGG P R+  +               F    Y+V L E
Sbjct: 204 LVLERPLDREKQSALQIILTALDGGIPARTGISMIKIIISDINDNSPLFSQELYQVSLTE 263

Query: 378 DEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435
             P  T V+ + ATDADE  +  + Y ++  +   +   T     G I     LDF+  +
Sbjct: 264 SAPVNTLVIQMNATDADEGVNGHITYYLSRISKAAQQKFTIDTETGEIRTKGTLDFETTK 323

Query: 436 RYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495
            Y + V A D GG    A V I I DAN+ AP       + S+ E++  GT + +++  D
Sbjct: 324 AYEMIVEAQDGGGLFSNAKVVIQIVDANDNAPEIILTSVSNSIPENSVPGTVIALINIRD 383

Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555
            D G N  +   ++  +  E  +     F        + T + LDRE M  Y +T+ A D
Sbjct: 384 IDSGENGNVYCQITDLLPFEITSSSSNYF-------RLLTTRNLDREEMHEYNITIKATD 436

Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615
            G PSLS T  +++ ++DVNDN PVF Q  Y   I E+   G+SV QV A+D D+  N +
Sbjct: 437 RGSPSLSTTKTIKLVLLDVNDNPPVFGQASYVVYIPENNPSGSSVFQVQASDPDLDDNAK 496

Query: 616 IHYELDPKDREE---GSFV-IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671
           I Y +   + +     S++ I+  +G++   +  D E +    ++ +A D G+PP +ST 
Sbjct: 497 ITYSIMNTNTDNFPVSSYISINSMTGILYAQRPFDYEQLREFGIQVMAKDNGSPPLNSTT 556

Query: 672 IVHIKIEDINDSPP--VFES----DCLTF-YISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
            V I I D+ND+ P  ++ S    D   F  +   S  G  + ++ A D D G NA + Y
Sbjct: 557 TVTICITDLNDNSPKILYPSTSADDSAQFEIVPRTSNKGELVAKVVAVDADSGHNAWLSY 616

Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTM-VDLDYESPRKKYELVIR-AASPPLWNDVRVEI 782
                 +S SF++    G    E+ T+ V  + E+ +++  ++++   SPP    + + +
Sbjct: 617 EFLQVSESMSFTISRHTG----EIRTLRVFPEKETLKQRLVVLVKDNGSPPRSATINLNL 672

Query: 783 LVTD 786
           +V D
Sbjct: 673 VVAD 676



 Score =  208 bits (507), Expect = 2e-51
 Identities = 143/439 (32%), Positives = 225/439 (51%), Gaps = 23/439 (5%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSI-TSQNGRGL- 422
           F      +E+ E   PGT  +   A D D+  N L       N   + ++ TS +GR + 
Sbjct: 143 FSKDTMNLEITELTHPGTRFILGDALDPDDGMNSLQAYDISKNEYFKLNVKTSSDGRMIP 202

Query: 423 -ITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVF 479
            + + +PLD +++    + ++A D G   R+  +M++I I+D N+ +P+F    Y  S+ 
Sbjct: 203 ELVLERPLDREKQSALQIILTALDGGIPARTGISMIKIIISDINDNSPLFSQELYQVSLT 262

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           E AP+ T V+ ++ATD+D G+N  ITY LS  IS  A     Q+F I+ +TG I T   L
Sbjct: 263 ESAPVNTLVIQMNATDADEGVNGHITYYLS-RISKAA----QQKFTIDTETGEIRTKGTL 317

Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
           D ET   Y + V A+DGG   L     V I +VD NDN P       + +I E+++ GT 
Sbjct: 318 DFETTKAYEMIVEAQDGG--GLFSNAKVVIQIVDANDNAPEIILTSVSNSIPENSVPGTV 375

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR--TNKALDRESVATHDLKA 657
           ++ +   D D G NG ++ ++      E   +   +S   R  T + LDRE +  +++  
Sbjct: 376 IALINIRDIDSGENGNVYCQITDLLPFE---ITSSSSNYFRLLTTRNLDREEMHEYNITI 432

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
            A D G+P  S+T  + + + D+ND+PPVF       YI EN+P G+++ +++A DPD  
Sbjct: 433 KATDRGSPSLSTTKTIKLVLLDVNDNPPVFGQASYVVYIPENNPSGSSVFQVQASDPDLD 492

Query: 718 PNAVVHYSIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPP 773
            NA + YSI   +  N   S      S    L      DYE  R+ + + + A    SPP
Sbjct: 493 DNAKITYSIMNTNTDNFPVSSYISINSMTGILYAQRPFDYEQLRE-FGIQVMAKDNGSPP 551

Query: 774 LWNDVRVEILVTDVNDNAP 792
           L +   V I +TD+NDN+P
Sbjct: 552 LNSTTTVTICITDLNDNSP 570



 Score =  167 bits (406), Expect = 4e-39
 Identities = 128/404 (31%), Positives = 193/404 (47%), Gaps = 21/404 (5%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           V+I I D N+ +P F        + E    GT  ++  A D D G+N+   Y +S    N
Sbjct: 129 VEIEIKDINDNSPSFSKDTMNLEITELTHPGTRFILGDALDPDDGMNSLQAYDISK---N 185

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
           E    + +          +   + LDRE  S   + +TA DGG+P+ +  + ++I + D+
Sbjct: 186 EYFKLNVKTSSDGRMIPELVLERPLDREKQSALQIILTALDGGIPARTGISMIKIIISDI 245

Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR-EEGSFVID 633
           NDN P+F Q+LY  ++ E A V T V Q+ ATDAD G+NG I Y L    +  +  F ID
Sbjct: 246 NDNSPLFSQELYQVSLTESAPVNTLVIQMNATDADEGVNGHITYYLSRISKAAQQKFTID 305

Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693
             +G IRT   LD E+   +++   A DGG    ++ V+  I+I D ND+ P      ++
Sbjct: 306 TETGEIRTKGTLDFETTKAYEMIVEAQDGGGLFSNAKVV--IQIVDANDNAPEIILTSVS 363

Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753
             I ENS  GT I  I   D D G N  V+  I    D   F + T   S+   L+T  +
Sbjct: 364 NSIPENSVPGTVIALINIRDIDSGENGNVYCQI---TDLLPFEI-TSSSSNYFRLLTTRN 419

Query: 754 LDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV 810
           LD E    +Y + I+A    SP L     +++++ DVNDN PV      +    ++    
Sbjct: 420 LDREE-MHEYNITIKATDRGSPSLSTTKTIKLVLLDVNDNPPVFGQASYVVYIPENNPSG 478

Query: 811 GPFGRVPAYDADVTD--KLQYRILSGNNANL-----ILLNETTG 847
               +V A D D+ D  K+ Y I++ N  N      I +N  TG
Sbjct: 479 SSVFQVQASDPDLDDNAKITYSIMNTNTDNFPVSSYISINSMTG 522



 Score =  161 bits (392), Expect = 2e-37
 Identities = 134/471 (28%), Positives = 213/471 (45%), Gaps = 46/471 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +I + D ND+SP+F  + Y+ S+ E A   T V+ + ATD D G N  + Y +  ++   
Sbjct: 239 KIIISDINDNSPLFSQELYQVSLTESAPVNTLVIQMNATDADEGVNGHITYYLSRISK-- 296

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                            Q  F ID  +G + T+ +LD E    Y ++V+A D        
Sbjct: 297 ---------------AAQQKFTIDTETGEIRTKGTLDFETTKAYEMIVEAQDGGG----- 336

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           L S A + + I+D NDN P+    + + S+ E+ SV    VIA I   D D G N  +  
Sbjct: 337 LFSNAKVVIQIVDANDNAPEIILTSVSNSIPEN-SVPGT-VIALINIRDIDSGENGNVYC 394

Query: 190 AIIGGNTQMQFSIDSLSGD---VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            I      + F I S S +   +   + LD E++  Y + I+A D GSPS S T  + + 
Sbjct: 395 QI---TDLLPFEITSSSSNYFRLLTTRNLDREEMHEYNITIKATDRGSPSLSTTKTIKLV 451

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN-- 304
           + DVNDN P F  + +   + EN P G S+ +VQA D D   NA++TY++ + + T N  
Sbjct: 452 LLDVNDNPPVFGQASYVVYIPENNPSGSSVFQVQASDPDLDDNAKITYSIMNTN-TDNFP 510

Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
           V   I+I+  +G +Y     D E   ++ + V A D G PP ++T T             
Sbjct: 511 VSSYISINSMTGILYAQRPFDYEQLREFGIQVMAKDNGSPPLNSTTTVTICITDLNDNSP 570

Query: 365 XFM--------PGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSI 414
             +          Q+E+ +      G  V  + A DAD  +   L YE    +    F+I
Sbjct: 571 KILYPSTSADDSAQFEI-VPRTSNKGELVAKVVAVDADSGHNAWLSYEFLQVSESMSFTI 629

Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNY 465
           +   G   I   +    K+  +  L V   D+G    +A + +N+  A+N+
Sbjct: 630 SRHTGE--IRTLRVFPEKETLKQRLVVLVKDNGSPPRSATINLNLVVADNF 678


>UniRef50_A7SSF2 Cluster: Predicted protein; n=2; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 814

 Score =  237 bits (581), Expect = 2e-60
 Identities = 141/428 (32%), Positives = 229/428 (53%), Gaps = 24/428 (5%)

Query: 164 SVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY 223
           +VT    +  + A D D G N  + Y I+  + +  F+ +S +G VSL   LD E V  Y
Sbjct: 400 NVTSGTQVLTLFAHDRDEGINGQVFYYIVTSSVKGVFTTNSTTGVVSLTAELDRESVYQY 459

Query: 224 RLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY- 282
            +++ AQDGGSP R+ +  + + + D NDN P F T  +   +SE   IG  I+RV A  
Sbjct: 460 NMLVVAQDGGSPPRTASAHVKVEVLDCNDNPPVFTTLYYTLQLSEATSIGTRILRVSAND 519

Query: 283 --DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD 340
             D DEGVNAE+ Y + D      V    +I+  +G +     +D E ++ Y   V A+D
Sbjct: 520 RDDKDEGVNAEIRYFLKD----AIVSKKFSINDTTGQITIKQAVDYEERSSYSFEVFASD 575

Query: 341 GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNR 398
           GG+   + +++              F+P +Y V+L E+   GTPV  +TA+D D   + +
Sbjct: 576 GGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTPVTQVTASDLDSSLNGK 635

Query: 399 LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG----GRSDTAM 454
           + + I GGN+ G+F +  QN  G++T  + LD++    Y L + ATD G      S   M
Sbjct: 636 VLFSILGGNSDGKF-VIDQN-TGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGM 693

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           + +++ + N+ +PVF    Y+AS+ E+  +G  +L V+A+D D  +N ++ +S+      
Sbjct: 694 LHVSVVNINDNSPVFSQKMYSASIDENTTVGHVILRVTASDLDSSLNGKVLFSILE---- 749

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD--VEISVV 572
               + D +FV++  TG +TTNK LD E ++ Y L + A D G P L+ +    + +SVV
Sbjct: 750 ---GNSDGKFVVDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVV 806

Query: 573 DVNDNEPV 580
           ++NDN PV
Sbjct: 807 NINDNSPV 814



 Score =  237 bits (579), Expect = 4e-60
 Identities = 154/438 (35%), Positives = 233/438 (53%), Gaps = 29/438 (6%)

Query: 370 QYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
           +YE E+ E+   GT V+TL A D DE  + ++ Y I   + +G F  T+ +  G++++  
Sbjct: 392 RYEFEMYENVTSGTQVLTLFAHDRDEGINGQVFYYIVTSSVKGVF--TTNSTTGVVSLTA 449

Query: 428 PLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
            LD +   +Y + V A D G   R+ +A V++ + D N+  PVF    YT  + E   IG
Sbjct: 450 ELDRESVYQYNMLVVAQDGGSPPRTASAHVKVEVLDCNDNPPVFTTLYYTLQLSEATSIG 509

Query: 486 TTVLVVSATD---SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
           T +L VSA D    D G+NA+I Y L   I ++       +F IN  TG IT  + +D E
Sbjct: 510 TRILRVSANDRDDKDEGVNAEIRYFLKDAIVSK-------KFSINDTTGQITIKQAVDYE 562

Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
             S Y   V A DGG   L+ ++ V I+++DVNDN P F    Y   ++E+  +GT V+Q
Sbjct: 563 ERSSYSFEVFASDGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTPVTQ 622

Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
           V A+D D  LNG++ + +      +G FVID  +GV+ TNK+LD E V  + L   A D 
Sbjct: 623 VTASDLDSSLNGKVLFSI-LGGNSDGKFVIDQNTGVVTTNKSLDYEDVTEYTLVIQATDC 681

Query: 663 GTPPQSSTV--IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
           G PP +S+   ++H+ + +IND+ PVF     +  I EN+ +G  I  + A D D   N 
Sbjct: 682 GDPPLNSSQPGMLHVSVVNINDNSPVFSQKMYSASIDENTTVGHVILRVTASDLDSSLNG 741

Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWND 777
            V +SI  G+    F ++   G     + T   LDYE    +Y LVI+A     PPL + 
Sbjct: 742 KVLFSILEGNSDGKFVVDQNTG----VVTTNKSLDYEDV-TEYTLVIQATDCGDPPLNSS 796

Query: 778 V--RVEILVTDVNDNAPV 793
               + + V ++NDN+PV
Sbjct: 797 QPGMLHVSVVNINDNSPV 814



 Score =  237 bits (579), Expect = 4e-60
 Identities = 143/436 (32%), Positives = 237/436 (54%), Gaps = 25/436 (5%)

Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321
           ++  + ENV  G  ++ + A+D DEG+N ++ Y +     T +V    T +  +G V  +
Sbjct: 393 YEFEMYENVTSGTQVLTLFAHDRDEGINGQVFYYIV----TSSVKGVFTTNSTTGVVSLT 448

Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381
            +LDRE+  +Y +LV A DGG PPR+A+A               F    Y ++L+E    
Sbjct: 449 AELDRESVYQYNMLVVAQDGGSPPRTASAHVKVEVLDCNDNPPVFTTLYYTLQLSEATSI 508

Query: 382 GTPVVTLTATDADEDN-----RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436
           GT ++ ++A D D+ +      + Y +       +FSI    G+  IT+ Q +D+++   
Sbjct: 509 GTRILRVSANDRDDKDEGVNAEIRYFLKDAIVSKKFSINDTTGQ--ITIKQAVDYEERSS 566

Query: 437 YVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494
           Y   V A+D G    + ++ V+I I D N+  P F    Y   + E+  IGT V  V+A+
Sbjct: 567 YSFEVFASDGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTPVTQVTAS 626

Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554
           D D  +N ++ +S+          + D +FVI+  TG +TTNK LD E ++ Y L + A 
Sbjct: 627 DLDSSLNGKVLFSILG-------GNSDGKFVIDQNTGVVTTNKSLDYEDVTEYTLVIQAT 679

Query: 555 DGGVPSLSDTTD--VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612
           D G P L+ +    + +SVV++NDN PVF Q++Y+A+I E+  VG  + +V A+D D  L
Sbjct: 680 DCGDPPLNSSQPGMLHVSVVNINDNSPVFSQKMYSASIDENTTVGHVILRVTASDLDSSL 739

Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV- 671
           NG++ + +  +   +G FV+D  +GV+ TNK+LD E V  + L   A D G PP +S+  
Sbjct: 740 NGKVLFSI-LEGNSDGKFVVDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQP 798

Query: 672 -IVHIKIEDINDSPPV 686
            ++H+ + +IND+ PV
Sbjct: 799 GMLHVSVVNINDNSPV 814



 Score =  202 bits (494), Expect = 8e-50
 Identities = 139/452 (30%), Positives = 223/452 (49%), Gaps = 37/452 (8%)

Query: 26  QQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXX 85
           ++YE  + E  +SGT VLTL A D+D G N +V Y I  VT+                  
Sbjct: 391 RRYEFEMYENVTSGTQVLTLFAHDRDEGINGQVFYYI--VTSS----------------- 431

Query: 86  VQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145
           V+ VF  +  +G +   A LDRE V +Y +LV A D  SP     +++A + V ++D ND
Sbjct: 432 VKGVFTTNSTTGVVSLTAELDRESVYQYNMLVVAQDGGSPPR---TASAHVKVEVLDCND 488

Query: 146 NYPQFSEKTYTVSVDEDISVTDNPV-IAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS 204
           N P F+   YT+ + E  S+    + ++     D D G N+ IRY +       +FSI+ 
Sbjct: 489 NPPVFTTLYYTLQLSEATSIGTRILRVSANDRDDKDEGVNAEIRYFLKDAIVSKKFSIND 548

Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
            +G +++ + +DYE+  SY   + A DGG    + ++ + I I DVNDN P F  + +  
Sbjct: 549 TTGQITIKQAVDYEERSSYSFEVFASDGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYV 608

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
            + ENV IG  + +V A D D  +N ++ +++      GN D    ID  +G V T+  L
Sbjct: 609 QLVENVAIGTPVTQVTASDLDSSLNGKVLFSILG----GNSDGKFVIDQNTGVVTTNKSL 664

Query: 325 DRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382
           D E   +Y L++ ATD GDPP   S                  F    Y   + E+   G
Sbjct: 665 DYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDNSPVFSQKMYSASIDENTTVG 724

Query: 383 TPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440
             ++ +TA+D D   + ++ + I  GN+ G+F +  QN  G++T  + LD++    Y L 
Sbjct: 725 HVILRVTASDLDSSLNGKVLFSILEGNSDGKF-VVDQN-TGVVTTNKSLDYEDVTEYTLV 782

Query: 441 VSATDSG----GRSDTAMVQINITDANNYAPV 468
           + ATD G      S   M+ +++ + N+ +PV
Sbjct: 783 IQATDCGDPPLNSSQPGMLHVSVVNINDNSPV 814



 Score =  190 bits (463), Expect = 5e-46
 Identities = 130/409 (31%), Positives = 201/409 (49%), Gaps = 25/409 (6%)

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ-FSIDSLS 206
           P F++  Y+  + ED +V     +  + A D D   N+ + Y+I+  +T+   F ID+++
Sbjct: 1   PIFNQTLYSAIIPEDFTV--GGTLLTVLARDQDAALNARVTYSIVSFSTESDYFVIDNIT 58

Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266
           G V   K  DYE  R Y   +RA+D GSP RS    + + I D NDN P F    ++  V
Sbjct: 59  GVVRSSKEFDYETQRMYSFSVRAEDRGSPIRSAIATIHVQITDTNDNRPIFQPMEYETRV 118

Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326
           SEN P+G  + RV+A D D   NA+L Y++ +    GN +   TID  +G + T  + D 
Sbjct: 119 SENTPLGTIVARVKAVDKDSTSNADLIYSIQN----GNNNGSFTIDNSTGEIMTRKEFDF 174

Query: 327 ETQAKYQLLVTATDGGDPPRSAT--ATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
           E   +Y L ++ +D G P  S+   A               F   +Y   + E+   GT 
Sbjct: 175 EKTERYNLTISVSDTGVPALSSLNFANVVIIVVDENDNPPEFAQKRYTATVYENFTVGTV 234

Query: 385 VVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
           V+ +TA D D   +  L Y I  GNT   F I + +G   I++ +PLD +    Y L + 
Sbjct: 235 VLRVTAHDKDSGPNAMLKYSIHSGNTDDAFVIIADSGD--ISLDKPLDKETIENYTLVLI 292

Query: 443 ATDSG----GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498
            TD G          +V + ++  N +AP F N  Y AS+ E+ P+GT+++ V A + DV
Sbjct: 293 VTDMGIPPLESIKRMVVNVIVSGVNEHAPRFLNEFYNASIPENLPLGTSIVRVRAVEDDV 352

Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
            + A+  Y +    S++        F++N QTG IT  + LD ET   Y
Sbjct: 353 SVGARFIYVIKDAASSKV-------FLVN-QTGDITLARELDYETRRRY 393



 Score =  187 bits (455), Expect = 4e-45
 Identities = 133/423 (31%), Positives = 198/423 (46%), Gaps = 36/423 (8%)

Query: 21  PVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXX 80
           P+F    Y A + E  + G T+LT+ A DQD   NA V Y+I   + ++           
Sbjct: 1   PIFNQTLYSAIIPEDFTVGGTLLTVLARDQDAALNARVTYSIVSFSTES----------- 49

Query: 81  XXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNI 140
                  D F ID  +G + +    D E    Y+  V+A D+ SP+    S+ ATIHV I
Sbjct: 50  -------DYFVIDNITGVVRSSKEFDYETQRMYSFSVRAEDRGSPIR---SAIATIHVQI 99

Query: 141 IDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQF 200
            D NDN P F    Y   V E+  +    ++A++KA D D  +N+ + Y+I  GN    F
Sbjct: 100 TDTNDNRPIFQPMEYETRVSENTPL--GTIVARVKAVDKDSTSNADLIYSIQNGNNNGSF 157

Query: 201 SIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS--NTTQLLINIRDVNDNAPRFY 258
           +ID+ +G++   K  D+E+   Y L I   D G P+ S  N   ++I + D NDN P F 
Sbjct: 158 TIDNSTGEIMTRKEFDFEKTERYNLTISVSDTGVPALSSLNFANVVIIVVDENDNPPEFA 217

Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV 318
              +  +V EN  +G  ++RV A+D D G NA L Y++    ++GN D    I   SG +
Sbjct: 218 QKRYTATVYENFTVGTVVLRVTAHDKDSGPNAMLKYSI----HSGNTDDAFVIIADSGDI 273

Query: 319 YTSGQLDRETQAKYQLLVTATDGGDPPRSA--TATXXXXXXXXXXXXXXFMPGQYEVELA 376
                LD+ET   Y L++  TD G PP  +                   F+   Y   + 
Sbjct: 274 SLDKPLDKETIENYTLVLIVTDMGIPPLESIKRMVVNVIVSGVNEHAPRFLNEFYNASIP 333

Query: 377 EDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434
           E+ P GT +V + A + D     R  Y I    +   F +   N  G IT+A+ LD++  
Sbjct: 334 ENLPLGTSIVRVRAVEDDVSVGARFIYVIKDAASSKVFLV---NQTGDITLARELDYETR 390

Query: 435 RRY 437
           RRY
Sbjct: 391 RRY 393



 Score =  186 bits (454), Expect = 6e-45
 Identities = 115/347 (33%), Positives = 188/347 (54%), Gaps = 33/347 (9%)

Query: 8   HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKAT---DQDIGKNAEVEYTIEL 64
           H ++ VLDCND+ PVF    Y   + E  S GT +L + A    D+D G NAE+ Y +  
Sbjct: 478 HVKVEVLDCNDNPPVFTTLYYTLQLSEATSIGTRILRVSANDRDDKDEGVNAEIRYFL-- 535

Query: 65  VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS 124
                   +DA          V   F I+  +G +  + ++D E+ + Y+  V A+D   
Sbjct: 536 --------KDA---------IVSKKFSINDTTGQITIKQAVDYEERSSYSFEVFASDGGE 578

Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184
               RL+ ++++ + IID NDN P F    Y V + E++++   PV  ++ A+D D   N
Sbjct: 579 A---RLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAI-GTPV-TQVTASDLDSSLN 633

Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQ 242
             + ++I+GGN+  +F ID  +G V+  K+LDYE V  Y LVI+A D G P  + S    
Sbjct: 634 GKVLFSILGGNSDGKFVIDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGM 693

Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
           L +++ ++NDN+P F   ++  S+ EN  +G+ I+RV A D D  +N ++ +++ +    
Sbjct: 694 LHVSVVNINDNSPVFSQKMYSASIDENTTVGHVILRVTASDLDSSLNGKVLFSILE---- 749

Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT 349
           GN D    +D  +G V T+  LD E   +Y L++ ATD GDPP +++
Sbjct: 750 GNSDGKFVVDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSS 796



 Score =  186 bits (452), Expect = 1e-44
 Identities = 133/418 (31%), Positives = 209/418 (50%), Gaps = 26/418 (6%)

Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
           P+F    Y+A + ED  +G T+L V A D D  +NA++TYS+ S  S E+       FVI
Sbjct: 1   PIFNQTLYSAIIPEDFTVGGTLLTVLARDQDAALNARVTYSIVS-FSTES-----DYFVI 54

Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586
           +  TG + ++K  D ET   Y  +V A D G P  S    + + + D NDN P+F+   Y
Sbjct: 55  DNITGVVRSSKEFDYETQRMYSFSVRAEDRGSPIRSAIATIHVQITDTNDNRPIFQPMEY 114

Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646
              + E+  +GT V++V A D D   N  + Y +       GSF ID ++G I T K  D
Sbjct: 115 ETRVSENTPLGTIVARVKAVDKDSTSNADLIYSIQ-NGNNNGSFTIDNSTGEIMTRKEFD 173

Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKI--EDINDSPPVFESDCLTFYISENSPIGT 704
            E    ++L     D G P  SS    ++ I   D ND+PP F     T  + EN  +GT
Sbjct: 174 FEKTERYNLTISVSDTGVPALSSLNFANVVIIVVDENDNPPEFAQKRYTATVYENFTVGT 233

Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764
            +  + AHD D GPNA++ YSI  G+  ++F +     +D  ++     LD E+  + Y 
Sbjct: 234 VVLRVTAHDKDSGPNAMLKYSIHSGNTDDAFVII----ADSGDISLDKPLDKET-IENYT 288

Query: 765 LVIRAAS---PPLWNDVR--VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPA 818
           LV+       PPL +  R  V ++V+ VN++AP   + +    +  +  P+G    RV A
Sbjct: 289 LVLIVTDMGIPPLESIKRMVVNVIVSGVNEHAPRFLN-EFYNASIPENLPLGTSIVRVRA 347

Query: 819 YDADVT--DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV--SVTDG 872
            + DV+   +  Y I    ++ + L+N+ TG +TL+ +L+    +    E+  +VT G
Sbjct: 348 VEDDVSVGARFIYVIKDAASSKVFLVNQ-TGDITLARELDYETRRRYEFEMYENVTSG 404



 Score =  179 bits (436), Expect = 9e-43
 Identities = 109/329 (33%), Positives = 175/329 (53%), Gaps = 31/329 (9%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           IH QI   D ND+ P+F+  +YE  V E    GT V  +KA D+D   NA++ Y+I+   
Sbjct: 95  IHVQIT--DTNDNRPIFQPMEYETRVSENTPLGTIVARVKAVDKDSTSNADLIYSIQ--- 149

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
               N  +               F ID  +G ++TR   D EK  RY + +  +D   P 
Sbjct: 150 ----NGNNNGS------------FTIDNSTGEIMTRKEFDFEKTERYNLTISVSDTGVPA 193

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
              L+  A + + ++D+NDN P+F++K YT +V E+ +V    V+ ++ A D D G N+ 
Sbjct: 194 LSSLNF-ANVVIIVVDENDNPPEFAQKRYTATVYENFTV--GTVVLRVTAHDKDSGPNAM 250

Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           ++Y+I  GNT   F I + SGD+SL K LD E + +Y LV+   D G P   +  ++++N
Sbjct: 251 LKYSIHSGNTDDAFVIIADSGDISLDKPLDKETIENYTLVLIVTDMGIPPLESIKRMVVN 310

Query: 247 --IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
             +  VN++APRF    +  S+ EN+P+G SIVRV+A + D  V A   Y + D      
Sbjct: 311 VIVSGVNEHAPRFLNEFYNASIPENLPLGTSIVRVRAVEDDVSVGARFIYVIKDA----- 365

Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQ 333
               + +  ++G +  + +LD ET+ +Y+
Sbjct: 366 ASSKVFLVNQTGDITLARELDYETRRRYE 394



 Score =  170 bits (414), Expect = 4e-40
 Identities = 129/410 (31%), Positives = 199/410 (48%), Gaps = 27/410 (6%)

Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
           Y   ++E+   GT VL + A D D GIN Q+ Y + +  S + V      F  N  TG +
Sbjct: 393 YEFEMYENVTSGTQVLTLFAHDRDEGINGQVFYYIVTS-SVKGV------FTTNSTTGVV 445

Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593
           +    LDRE++  Y + V A+DGG P  + +  V++ V+D NDN PVF    YT  + E 
Sbjct: 446 SLTAELDRESVYQYNMLVVAQDGGSPPRTASAHVKVEVLDCNDNPPVFTTLYYTLQLSEA 505

Query: 594 ALVGTSVSQVGATDAD---VGLNGRIHYELDPKDR-EEGSFVIDPASGVIRTNKALDRES 649
             +GT + +V A D D    G+N  I Y L  KD      F I+  +G I   +A+D E 
Sbjct: 506 TSIGTRILRVSANDRDDKDEGVNAEIRYFL--KDAIVSKKFSINDTTGQITIKQAVDYEE 563

Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
            +++  +  A DGG    + +  V I I D+ND+ P F        + EN  IGT + ++
Sbjct: 564 RSSYSFEVFASDGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTPVTQV 623

Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
            A D D   N  V +SI GG+    F ++   G     + T   LDYE   + Y LVI+A
Sbjct: 624 TASDLDSSLNGKVLFSILGGNSDGKFVIDQNTGV----VTTNKSLDYEDVTE-YTLVIQA 678

Query: 770 AS---PPLWNDV--RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDAD- 822
                PPL +     + + V ++NDN+PV    ++   +  +   VG    RV A D D 
Sbjct: 679 TDCGDPPLNSSQPGMLHVSVVNINDNSPVFSQ-KMYSASIDENTTVGHVILRVTASDLDS 737

Query: 823 -VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            +  K+ + IL GN+    ++++ TG +T +  L+       T+ +  TD
Sbjct: 738 SLNGKVLFSILEGNSDGKFVVDQNTGVVTTNKSLDYEDVTEYTLVIQATD 787



 Score =  157 bits (382), Expect = 3e-36
 Identities = 103/318 (32%), Positives = 169/318 (53%), Gaps = 15/318 (4%)

Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638
           P+F Q LY+A I ED  VG ++  V A D D  LN R+ Y +     E   FVID  +GV
Sbjct: 1   PIFNQTLYSAIIPEDFTVGGTLLTVLARDQDAALNARVTYSIVSFSTESDYFVIDNITGV 60

Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698
           +R++K  D E+   +     A D G+P +S+   +H++I D ND+ P+F+       +SE
Sbjct: 61  VRSSKEFDYETQRMYSFSVRAEDRGSPIRSAIATIHVQITDTNDNRPIFQPMEYETRVSE 120

Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758
           N+P+GT +  ++A D D   NA + YSI+ G+++ SF+++   G    E++T  + D+E 
Sbjct: 121 NTPLGTIVARVKAVDKDSTSNADLIYSIQNGNNNGSFTIDNSTG----EIMTRKEFDFEK 176

Query: 759 PRKKYELVIRAAS---PPL--WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF 813
             ++Y L I  +    P L   N   V I+V D NDN P     +     Y++ F VG  
Sbjct: 177 -TERYNLTISVSDTGVPALSSLNFANVVIIVVDENDNPPEFAQKRYTATVYEN-FTVGTV 234

Query: 814 G-RVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVT 870
             RV A+D D      L+Y I SGN  +  ++   +G ++L   L+    +  T+ + VT
Sbjct: 235 VLRVTAHDKDSGPNAMLKYSIHSGNTDDAFVIIADSGDISLDKPLDKETIENYTLVLIVT 294

Query: 871 D-GVNEIKAMMQLSVRLI 887
           D G+  ++++ ++ V +I
Sbjct: 295 DMGIPPLESIKRMVVNVI 312



 Score = 67.7 bits (158), Expect = 4e-09
 Identities = 45/147 (30%), Positives = 74/147 (50%), Gaps = 22/147 (14%)

Query: 2   SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
           S P  +H  ++V++ ND+SPVF  + Y AS+ E  + G  +L + A+D D   N +V ++
Sbjct: 689 SQPGMLH--VSVVNINDNSPVFSQKMYSASIDENTTVGHVILRVTASDLDSSLNGKVLFS 746

Query: 62  IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121
           I    +D                     F +D  +G + T  SLD E V  YT++++ATD
Sbjct: 747 ILEGNSD-------------------GKFVVDQNTGVVTTNKSLDYEDVTEYTLVIQATD 787

Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYP 148
              P  +  S    +HV++++ NDN P
Sbjct: 788 CGDPPLNS-SQPGMLHVSVVNINDNSP 813



 Score = 55.6 bits (128), Expect = 2e-05
 Identities = 55/201 (27%), Positives = 83/201 (41%), Gaps = 14/201 (6%)

Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753
           F + EN   GT +  + AHD DEG N  V Y I        F+  +  G     +    +
Sbjct: 395 FEMYENVTSGTQVLTLFAHDRDEGINGQVFYYIVTSSVKGVFTTNSTTGV----VSLTAE 450

Query: 754 LDYESPRKKYELVIR--AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811
           LD ES  +   LV+     SPP      V++ V D NDN PV            +   +G
Sbjct: 451 LDRESVYQYNMLVVAQDGGSPPRTASAHVKVEVLDCNDNPPVFTTLYYTLQ-LSEATSIG 509

Query: 812 P-FGRVPAYDADVTDK-----LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATM 865
               RV A D D  D+     ++Y +     +    +N+TTG +T+   ++       + 
Sbjct: 510 TRILRVSANDRDDKDEGVNAEIRYFLKDAIVSKKFSINDTTGQITIKQAVDYEERSSYSF 569

Query: 866 EVSVTDGVNEIKAMMQLSVRL 886
           EV  +DG  E +     SVR+
Sbjct: 570 EVFASDG-GEARLTGSSSVRI 589


>UniRef50_Q9VJB6 Cluster: Putative neural-cadherin 2 precursor; n=5;
            Diptera|Rep: Putative neural-cadherin 2 precursor -
            Drosophila melanogaster (Fruit fly)
          Length = 2215

 Score =  237 bits (581), Expect = 2e-60
 Identities = 297/1169 (25%), Positives = 468/1169 (40%), Gaps = 142/1169 (12%)

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDADEDN-----RLHYEITGG---NTRGRFSITSQ 417
            F  G Y   + E+   G+ V+T++A D D+ N     +L Y I         G      +
Sbjct: 422  FPQGIYFGNVTENGTAGSSVMTMSAVDYDDPNESTNAKLIYSIEKNVIEEETGAPIFEIE 481

Query: 418  NGRGLI-TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA 476
               GLI T    LD ++   Y + V A D GG   T    I + D N+  P F    +  
Sbjct: 482  PETGLIKTAVCCLDRERTPDYSIQVVAMDGGGLKGTGTASIRVKDLNDMPPQFTKDEWVT 541

Query: 477  SVFEDAPI---GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ-TGA 532
             V E        T +L V+  D D     Q  Y +   + N          V N   TG+
Sbjct: 542  EVDETNGTYIPETPILTVTVQDEDETNTFQ--YKV---VPNSGFGADKFAMVRNGDGTGS 596

Query: 533  ITTNKLLDRET---MSGYLLTVTARDGGV--PSLSDTTDVEISVV-----DVNDNEPVFK 582
            +   + LD E     SG+   +   D G   P  SD   V  S V     D+NDN P F 
Sbjct: 597  LKIIQPLDYEDPLQSSGFRFRIQVNDKGDDGPGGSDKYHVAYSWVVVKLRDINDNVPKFD 656

Query: 583  QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642
            ++    +I ED  VGT + Q  ATDAD G + ++ Y++      +  F I    G +   
Sbjct: 657  REHIEVSIYEDTKVGTILEQFKATDADQGGHSKVAYKIVRSTNRKRQFAISDR-GAVSIQ 715

Query: 643  KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
            + LDRE+   H ++ +AID G+P +++T  + + ++D+ND+ P F  D     + EN   
Sbjct: 716  RPLDRETQDRHHIQILAIDDGSPARTATATLTVIVKDVNDNAPTFAQDYKPT-LPENVS- 773

Query: 703  GTTIGEIRAHDPDE------GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD--- 753
            G  I E+ A DPD+      GP       +   +    F +E  +  D    V ++    
Sbjct: 774  GKKILEVAAKDPDDRLRGNGGPFTFRLDPLASDEIKAGFKVEYDRRGDNENGVAIISSLR 833

Query: 754  -LDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809
              D E+ +K Y + I      +P +     + + + DVNDN        ++  NY+    
Sbjct: 834  PFDREA-QKSYAIPIEIKDNGAPAMTGTSTLTVTIGDVNDNKMQPGSKSVLVYNYQGQSQ 892

Query: 810  VGPFGRVPAYDA---DVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATME 866
              P GRV   D    DV DK  Y  +  +      L+  TG +T+         +L    
Sbjct: 893  DTPIGRVYVNDPDDWDVPDKKYYWEVQEHQR--FKLDTDTGILTMRAGTRRGRYQLRFKV 950

Query: 867  VSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFL---SPL--------LGF 915
                 G  +I A + ++VR IT E +  + ++RL+ +T E F+   +P+        L  
Sbjct: 951  YDREHGQEDIPANLSVTVRDITAEAVQQAGSMRLSHITDEDFVRTWNPVKNQVEPSKLER 1010

Query: 916  FIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHL 975
            F + LA ++   ++N+ +FSVQ        + +V F+AR        +    P++    L
Sbjct: 1011 FRNKLAELLYTDRDNVDVFSVQLKEGSPYPLTDVHFAAR--------SATQQPYFKAVRL 1062

Query: 976  RERVYLHRTTLARLATVQVLPFDDNICVHE---PCLNFEECLTVLKFGNASGFVNSDSVL 1032
               V +HR  + +   + +   + N C+HE    C     C + ++ G     V+ +   
Sbjct: 1063 NGVVQMHREEIEKDVGLNITMVNINECLHEGKGKC-GSNSCTSKVELGKKPYTVSVNRTA 1121

Query: 1033 FRPIYPVTSFTCQC-PEGFT--GVNCETILTKASCEVDGDGSICRSGSQCVARREGGILC 1089
               +    S  C C    FT    NC T              +C +G +CV  R G   C
Sbjct: 1122 LVGVRLDISAQCVCRARNFTHQDHNCRT-------------HLCYNGGRCVETRNGP-KC 1167

Query: 1090 QGCSIDAAYTTAVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNG--- 1146
              C +   Y    C+   RSF  + +  +P L+     HL L+F T+   GL+LYNG   
Sbjct: 1168 VACPV--GYNGPRCQQSTRSFRGNGWAWYPPLQLCQESHLSLEFITRVADGLILYNGPIV 1225

Query: 1147 --RYNER--HDFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIE 1202
              +  E    DF+ALEL        G P L   F  G  +  +  +  + DG WH ++I 
Sbjct: 1226 PPKPEETVISDFIALEL------EQGYPRLLIDFGSGTLELRVKTKKTLDDGVWHRLDIF 1279

Query: 1203 YFNRTITMILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPL 1262
            +    + M++D C    +L    + G       F      AR +IP       L+L  PL
Sbjct: 1280 WDTENVRMVVDFCR--TALVSEMEDGTP---PEFDDNACQARGQIPPFA--ESLNLNQPL 1332

Query: 1263 QIGGLPN-------IPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRS 1315
            Q+GGL             +   +K F GCI +   + +  DL        +   CP+   
Sbjct: 1333 QLGGLYRQHFDQTLYNWQYAFSSKGFDGCIRNVIHNSEHYDLAFPALARNSFPACPQTDE 1392

Query: 1316 RC----SSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLR 1371
             C     +A C+    C        C C+ G  G  C   T  P  F     + F     
Sbjct: 1393 VCLKTEHTARCWEHGNCVASLVQAKCHCQPGWMGPGCNVPT-IPTTFKAQSYVKFALSFE 1451

Query: 1372 PIQLPWLNALSIRTRQR--DAFVMS---------IQLKSGLLHYSYNGETM-------YL 1413
            P +      L  RTR++  + F +S         ++L+ G L + YN  +M        L
Sbjct: 1452 PDRFSTQLQLRFRTREQGGELFRVSDQHHREYAILELRRGHLQFRYNLNSMRNEEQLLTL 1511

Query: 1414 PMATLSDGAWHRIEIKWLGTDISVTVDYG 1442
                ++DG WH I I   G+   + +D G
Sbjct: 1512 TAIAVNDGQWHVIRISRYGSAALMELDGG 1540



 Score =  196 bits (477), Expect = 1e-47
 Identities = 162/589 (27%), Positives = 272/589 (46%), Gaps = 58/589 (9%)

Query: 198 MQFSIDSLSGDVS---LVKTLDYEQVRS---YRLVIRAQDGGSPSRSNTTQLLINIRDVN 251
           MQF +D+   + S   L+  LD +Q      +R  + AQD G         + +N++D+N
Sbjct: 357 MQFRVDNSFNEKSNNRLLCPLDRDQPNGRPQWRFTVFAQDEGGEGLVGYADIQVNLKDIN 416

Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD---EGVNAELTYTMTDKDYTGNVDLP 308
           DNAP+F   ++  +V+EN   G S++ + A D D   E  NA+L Y++           P
Sbjct: 417 DNAPQFPQGIYFGNVTENGTAGSSVMTMSAVDYDDPNESTNAKLIYSIEKNVIEEETGAP 476

Query: 309 I-TIDPRSGWVYTS-GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
           I  I+P +G + T+   LDRE    Y + V A DGG      T T              F
Sbjct: 477 IFEIEPETGLIKTAVCCLDRERTPDYSIQVVAMDGGG--LKGTGTASIRVKDLNDMPPQF 534

Query: 367 MPGQYEVELAEDEP---PGTPVVTLTATDADEDNRLHYEITGGNTRG--RFS-ITSQNGR 420
              ++  E+ E      P TP++T+T  D DE N   Y++   +  G  +F+ + + +G 
Sbjct: 535 TKDEWVTEVDETNGTYIPETPILTVTVQDEDETNTFQYKVVPNSGFGADKFAMVRNGDGT 594

Query: 421 GLITVAQPLDFK---QERRYVLTVSATDSG----GRSDT-----AMVQINITDANNYAPV 468
           G + + QPLD++   Q   +   +   D G    G SD      + V + + D N+  P 
Sbjct: 595 GSLKIIQPLDYEDPLQSSGFRFRIQVNDKGDDGPGGSDKYHVAYSWVVVKLRDINDNVPK 654

Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528
           F+      S++ED  +GT +    ATD+D G ++++ Y +    + +      +QF I+ 
Sbjct: 655 FDREHIEVSIYEDTKVGTILEQFKATDADQGGHSKVAYKIVRSTNRK------RQFAISD 708

Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588
           + GA++  + LDRET   + + + A D G P+ + T  + + V DVNDN P F Q  Y  
Sbjct: 709 R-GAVSIQRPLDRETQDRHHIQILAIDDGSPARTATATLTVIVKDVNDNAPTFAQD-YKP 766

Query: 589 NIMEDALVGTSVSQVGATDADVGLNGR---IHYELDP--KDREEGSFVI------DPASG 637
            + E+ + G  + +V A D D  L G      + LDP   D  +  F +      D  +G
Sbjct: 767 TLPEN-VSGKKILEVAAKDPDDRLRGNGGPFTFRLDPLASDEIKAGFKVEYDRRGDNENG 825

Query: 638 V--IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695
           V  I + +  DRE+  ++ +     D G P  + T  + + I D+ND+     S  +  Y
Sbjct: 826 VAIISSLRPFDREAQKSYAIPIEIKDNGAPAMTGTSTLTVTIGDVNDNKMQPGSKSVLVY 885

Query: 696 ISENSPIGTTIGEIRAHDPDEG--PNAVVHYSIKGGDDSNSFSLETRQG 742
             +     T IG +  +DPD+   P+   ++ ++   +   F L+T  G
Sbjct: 886 NYQGQSQDTPIGRVYVNDPDDWDVPDKKYYWEVQ---EHQRFKLDTDTG 931



 Score =  128 bits (310), Expect = 2e-27
 Identities = 122/490 (24%), Positives = 217/490 (44%), Gaps = 61/490 (12%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDI---GKNAEVEYTIELVT 66
           Q+N+ D ND++P F    Y  +V E  ++G++V+T+ A D D      NA++ Y+IE   
Sbjct: 409 QVNLKDINDNAPQFPQGIYFGNVTENGTAGSSVMTMSAVDYDDPNESTNAKLIYSIE--- 465

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS-LDREKVARYTVLVKATDQASP 125
            + +  E               +F I+  +G + T    LDRE+   Y++ V A D    
Sbjct: 466 KNVIEEETGA-----------PIFEIEPETGLIKTAVCCLDRERTPDYSIQVVAMDGGG- 513

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
               L  T T  + + D ND  PQF++  +   VDE  + T  P    +  T  D    +
Sbjct: 514 ----LKGTGTASIRVKDLNDMPPQFTKDEWVTEVDE-TNGTYIPETPILTVTVQDEDETN 568

Query: 186 AIRYAII-----GGNTQMQFSIDSLSGDVSLVKTLDYE---QVRSYRLVIRAQDGG--SP 235
             +Y ++     G +          +G + +++ LDYE   Q   +R  I+  D G   P
Sbjct: 569 TFQYKVVPNSGFGADKFAMVRNGDGTGSLKIIQPLDYEDPLQSSGFRFRIQVNDKGDDGP 628

Query: 236 SRSNT-----TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290
             S+      + +++ +RD+NDN P+F     + S+ E+  +G  + + +A DAD+G ++
Sbjct: 629 GGSDKYHVAYSWVVVKLRDINDNVPKFDREHIEVSIYEDTKVGTILEQFKATDADQGGHS 688

Query: 291 ELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350
           ++ Y +     + N      I  R G V     LDRETQ ++ + + A D G P R+ATA
Sbjct: 689 KVAYKIV---RSTNRKRQFAISDR-GAVSIQRPLDRETQDRHHIQILAIDDGSPARTATA 744

Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH--------YE 402
           T              F    Y+  L E+   G  ++ + A D D+  R +          
Sbjct: 745 TLTVIVKDVNDNAPTFAQ-DYKPTLPEN-VSGKKILEVAAKDPDDRLRGNGGPFTFRLDP 802

Query: 403 ITGGNTRGRFSI------TSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAM 454
           +     +  F +       ++NG  +I+  +P D + ++ Y + +   D+G    + T+ 
Sbjct: 803 LASDEIKAGFKVEYDRRGDNENGVAIISSLRPFDREAQKSYAIPIEIKDNGAPAMTGTST 862

Query: 455 VQINITDANN 464
           + + I D N+
Sbjct: 863 LTVTIGDVND 872



 Score =  110 bits (264), Expect = 6e-22
 Identities = 120/478 (25%), Positives = 210/478 (43%), Gaps = 42/478 (8%)

Query: 134 ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV-IAKIKATDADVGANSAIRYAII 192
           A I VN+ D NDN PQF +  Y  +V E+ +   + + ++ +   D +   N+ + Y+I 
Sbjct: 406 ADIQVNLKDINDNAPQFPQGIYFGNVTENGTAGSSVMTMSAVDYDDPNESTNAKLIYSIE 465

Query: 193 GGNTQMQFS--IDSLSGDVSLVKT----LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
               + +    I  +  +  L+KT    LD E+   Y + + A DGG    + T    I 
Sbjct: 466 KNVIEEETGAPIFEIEPETGLIKTAVCCLDRERTPDYSIQVVAMDGGGLKGTGTAS--IR 523

Query: 247 IRDVNDNAPRFYTSLFQESVSEN----VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
           ++D+ND  P+F    +   V E     +P    I+ V   D DE  N      + +  + 
Sbjct: 524 VKDLNDMPPQFTKDEWVTEVDETNGTYIP-ETPILTVTVQDEDE-TNTFQYKVVPNSGFG 581

Query: 303 GNVDLPITIDPRSGWVYTSGQLDRE---TQAKYQLLVTATDGGD--PPRS-----ATATX 352
            +    +     +G +     LD E     + ++  +   D GD  P  S     A +  
Sbjct: 582 ADKFAMVRNGDGTGSLKIIQPLDYEDPLQSSGFRFRIQVNDKGDDGPGGSDKYHVAYSWV 641

Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRG 410
                        F     EV + ED   GT +    ATDAD+   +++ Y+I     R 
Sbjct: 642 VVKLRDINDNVPKFDREHIEVSIYEDTKVGTILEQFKATDADQGGHSKVAYKIVRSTNRK 701

Query: 411 R-FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAP 467
           R F+I+    RG +++ +PLD + + R+ + + A D G   R+ TA + + + D N+ AP
Sbjct: 702 RQFAISD---RGAVSIQRPLDRETQDRHHIQILAIDDGSPARTATATLTVIVKDVNDNAP 758

Query: 468 VFENAPYTASVFEDAPIGTTVLVVSATDSD---VGINAQITYSLSSEISNEAVA----HH 520
            F    Y  ++ E+   G  +L V+A D D    G     T+ L    S+E  A     +
Sbjct: 759 TFAQ-DYKPTLPENVS-GKKILEVAAKDPDDRLRGNGGPFTFRLDPLASDEIKAGFKVEY 816

Query: 521 DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578
           D++         I++ +  DRE    Y + +  +D G P+++ T+ + +++ DVNDN+
Sbjct: 817 DRRGDNENGVAIISSLRPFDREAQKSYAIPIEIKDNGAPAMTGTSTLTVTIGDVNDNK 874



 Score =  105 bits (253), Expect = 1e-20
 Identities = 104/396 (26%), Positives = 175/396 (44%), Gaps = 39/396 (9%)

Query: 523 QFVINPQTGAITTNKLL---DRETMSG---YLLTVTARDGGVPSLSDTTDVEISVVDVND 576
           QF ++      + N+LL   DR+  +G   +  TV A+D G   L    D+++++ D+ND
Sbjct: 358 QFRVDNSFNEKSNNRLLCPLDRDQPNGRPQWRFTVFAQDEGGEGLVGYADIQVNLKDIND 417

Query: 577 NEPVFKQQLYTANIMEDALVGTSVSQVGATDAD---VGLNGRIHYELDPK--DREEGS-- 629
           N P F Q +Y  N+ E+   G+SV  + A D D      N ++ Y ++    + E G+  
Sbjct: 418 NAPQFPQGIYFGNVTENGTAGSSVMTMSAVDYDDPNESTNAKLIYSIEKNVIEEETGAPI 477

Query: 630 FVIDPASGVIRTNK-ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688
           F I+P +G+I+T    LDRE    + ++ VA+DGG    + T    I+++D+ND PP F 
Sbjct: 478 FEIEPETGLIKTAVCCLDRERTPDYSIQVVAMDGGGLKGTGT--ASIRVKDLNDMPPQFT 535

Query: 689 SDCLTFYISENSPIGTTIGE-----IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
            D     + E +  GT I E     +   D DE            G  ++ F++  R G 
Sbjct: 536 KDEWVTEVDETN--GTYIPETPILTVTVQDEDETNTFQYKVVPNSGFGADKFAM-VRNGD 592

Query: 744 DKAELVTMVDLDYESP------RKKYELVIRAASPPLWNDVR------VEILVTDVNDNA 791
               L  +  LDYE P      R + ++  +    P  +D        V + + D+NDN 
Sbjct: 593 GTGSLKIIQPLDYEDPLQSSGFRFRIQVNDKGDDGPGGSDKYHVAYSWVVVKLRDINDNV 652

Query: 792 PVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSM 849
           P      I  + Y+D        +  A DAD     K+ Y+I+   N          G++
Sbjct: 653 PKFDREHIEVSIYEDTKVGTILEQFKATDADQGGHSKVAYKIVRSTNRKRQFAISDRGAV 712

Query: 850 TLSPQLNTNVPKLATMEV-SVTDGVNEIKAMMQLSV 884
           ++   L+        +++ ++ DG     A   L+V
Sbjct: 713 SIQRPLDRETQDRHHIQILAIDDGSPARTATATLTV 748



 Score =  103 bits (246), Expect = 9e-20
 Identities = 88/299 (29%), Positives = 136/299 (45%), Gaps = 27/299 (9%)

Query: 138 VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG-NT 196
           V + D NDN P+F  +   VS+ ED  V    ++ + KATDAD G +S + Y I+   N 
Sbjct: 643 VKLRDINDNVPKFDREHIEVSIYEDTKV--GTILEQFKATDADQGGHSKVAYKIVRSTNR 700

Query: 197 QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256
           + QF+I    G VS+ + LD E    + + I A D GSP+R+ T  L + ++DVNDNAP 
Sbjct: 701 KRQFAISD-RGAVSIQRPLDRETQDRHHIQILAIDDGSPARTATATLTVIVKDVNDNAPT 759

Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADE---GVNAELTYTM----TDKDYTG-NVDLP 308
           F    ++ ++ ENV  G  I+ V A D D+   G     T+ +    +D+   G  V+  
Sbjct: 760 FAQD-YKPTLPENVS-GKKILEVAAKDPDDRLRGNGGPFTFRLDPLASDEIKAGFKVEYD 817

Query: 309 ITIDPRSGWVYTSG--QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
              D  +G    S     DRE Q  Y + +   D G P  + T T               
Sbjct: 818 RRGDNENGVAIISSLRPFDREAQKSYAIPIEIKDNGAP--AMTGTSTLTVTIGDVNDNKM 875

Query: 367 MPGQYEVEL--AEDEPPGTPVVTLTATDADE----DNRLHYEITGGNTRGRFSITSQNG 419
            PG   V +   + +   TP+  +   D D+    D + ++E+       RF + +  G
Sbjct: 876 QPGSKSVLVYNYQGQSQDTPIGRVYVNDPDDWDVPDKKYYWEV---QEHQRFKLDTDTG 931



 Score = 77.4 bits (182), Expect = 5e-12
 Identities = 52/142 (36%), Positives = 75/142 (52%), Gaps = 8/142 (5%)

Query: 395 EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM 454
           E   + Y+ITGGN    F++  QN  G+I VA PLD++   RY L + AT +   + T +
Sbjct: 178 ESTNIRYQITGGNIGNAFAV--QNTTGVIYVASPLDYETRPRYELRLEATRNRKNNYTTV 235

Query: 455 VQINITDANNYAPVFENAPYTASVFE--DAPIGTTVLVVSATDSDVGINAQITYSLSSE- 511
           V IN+ D N+  PVF+   Y   + E  D  +   +L V+ATD DV     I Y L+ + 
Sbjct: 236 V-INVRDVNDNPPVFDRQTYRTQITEEDDRNLPKRILQVTATDGDVDRPINIVYFLTGQG 294

Query: 512 ISNEAVAHHDQQFVINPQTGAI 533
           I  +  A  + +F IN  TG I
Sbjct: 295 IDPDNPA--NSKFDINRTTGDI 314



 Score = 60.1 bits (139), Expect = 9e-07
 Identities = 38/115 (33%), Positives = 59/115 (51%), Gaps = 9/115 (7%)

Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           IRY I GGN    F++ + +G + +   LDYE    Y L + A       ++N T ++IN
Sbjct: 182 IRYQITGGNIGNAFAVQNTTGVIYVASPLDYETRPRYELRLEATRN---RKNNYTTVVIN 238

Query: 247 IRDVNDNAPRFYTSLFQESVSE----NVPIGYSIVRVQAYDADEGVNAELTYTMT 297
           +RDVNDN P F    ++  ++E    N+P    I++V A D D      + Y +T
Sbjct: 239 VRDVNDNPPVFDRQTYRTQITEEDDRNLP--KRILQVTATDGDVDRPINIVYFLT 291



 Score = 53.6 bits (123), Expect = 8e-05
 Identities = 42/166 (25%), Positives = 69/166 (41%), Gaps = 12/166 (7%)

Query: 54  KNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARY 113
           K AE   T      D L  E            + + F +   +G +   + LD E   RY
Sbjct: 159 KMAEQYDTFIKFNHDQLQRESTNIRYQITGGNIGNAFAVQNTTGVIYVASPLDYETRPRY 218

Query: 114 TVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK 173
            + ++AT       +R ++  T+ +N+ D NDN P F  +TY   + E+        I +
Sbjct: 219 ELRLEAT------RNRKNNYTTVVINVRDVNDNPPVFDRQTYRTQITEEDDRNLPKRILQ 272

Query: 174 IKATDADVGANSAIRYAIIG------GNTQMQFSIDSLSGDVSLVK 213
           + ATD DV     I Y + G           +F I+  +GD+ ++K
Sbjct: 273 VTATDGDVDRPINIVYFLTGQGIDPDNPANSKFDINRTTGDIFVLK 318



 Score = 52.0 bits (119), Expect = 2e-04
 Identities = 46/128 (35%), Positives = 57/128 (44%), Gaps = 10/128 (7%)

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583
           F +   TG I     LD ET   Y L + A        ++ T V I+V DVNDN PVF +
Sbjct: 195 FAVQNTTGVIYVASPLDYETRPRYELRLEATRN---RKNNYTTVVINVRDVNDNPPVFDR 251

Query: 584 QLYTANIME--DALVGTSVSQVGATDADVGLNGRIHYEL-----DPKDREEGSFVIDPAS 636
           Q Y   I E  D  +   + QV ATD DV     I Y L     DP +     F I+  +
Sbjct: 252 QTYRTQITEEDDRNLPKRILQVTATDGDVDRPINIVYFLTGQGIDPDNPANSKFDINRTT 311

Query: 637 GVIRTNKA 644
           G I   KA
Sbjct: 312 GDIFVLKA 319



 Score = 44.4 bits (100), Expect = 0.046
 Identities = 29/82 (35%), Positives = 41/82 (50%), Gaps = 5/82 (6%)

Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771
           HD  +  +  + Y I GG+  N+F+++   G     +     LDYE+ R +YEL + A  
Sbjct: 172 HDQLQRESTNIRYQITGGNIGNAFAVQNTTGV----IYVASPLDYET-RPRYELRLEATR 226

Query: 772 PPLWNDVRVEILVTDVNDNAPV 793
               N   V I V DVNDN PV
Sbjct: 227 NRKNNYTTVVINVRDVNDNPPV 248



 Score = 39.5 bits (88), Expect = 1.3
 Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 5/91 (5%)

Query: 11  INVLDCNDHSPVFEMQQYEASVRE--GASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68
           INV D ND+ PVF+ Q Y   + E    +    +L + ATD D+ +   + Y    +T  
Sbjct: 237 INVRDVNDNPPVFDRQTYRTQITEEDDRNLPKRILQVTATDGDVDRPINIVY---FLTGQ 293

Query: 69  TLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL 99
            ++P++             D+F +  ++  L
Sbjct: 294 GIDPDNPANSKFDINRTTGDIFVLKAKTKRL 324



 Score = 38.7 bits (86), Expect = 2.3
 Identities = 18/42 (42%), Positives = 24/42 (57%), Gaps = 3/42 (7%)

Query: 1309 GCPEKRSRCSSAPCYNGAECSDLWD--TYICDCKEGHTGKDC 1348
            GC + R+ C   PC NGA C +L     Y C C EG+ G++C
Sbjct: 1690 GCVD-RNECLDLPCLNGATCINLEPRLRYRCICPEGYWGENC 1730



 Score = 37.9 bits (84), Expect = 4.0
 Identities = 28/109 (25%), Positives = 54/109 (49%), Gaps = 6/109 (5%)

Query: 629 SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688
           +F +   +GVI     LD E+   ++L+  A         +TV+++++  D+ND+PPVF+
Sbjct: 194 AFAVQNTTGVIYVASPLDYETRPRYELRLEATRN-RKNNYTTVVINVR--DVNDNPPVFD 250

Query: 689 SDCLTFYISENSP--IGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNS 734
                  I+E     +   I ++ A D D + P  +V++    G D ++
Sbjct: 251 RQTYRTQITEEDDRNLPKRILQVTATDGDVDRPINIVYFLTGQGIDPDN 299


>UniRef50_A4KCK1 Cluster: Protocadherin 2A37; n=12;
           Clupeocephala|Rep: Protocadherin 2A37 - Fugu rubripes
           (Japanese pufferfish) (Takifugu rubripes)
          Length = 1013

 Score =  237 bits (579), Expect = 4e-60
 Identities = 183/627 (29%), Positives = 289/627 (46%), Gaps = 29/627 (4%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F I+ ++G L     +DRE +  +T       +   V +       + V I+D NDN PQ
Sbjct: 78  FAINHKNGKLTVSDRIDRETICEFTGTCSLNLEV--VLENPLDVHNVEVEILDVNDNAPQ 135

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG-- 207
           F    Y + V E  ++T      +  A DAD G+NS  +Y +   +     S+   S   
Sbjct: 136 FPRDEYQLEVSES-ALTGTRFHIE-GAQDADDGSNSVKQYRLSRNDHLTLDSVKQFSNNK 193

Query: 208 --DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265
             ++ L K  D E + S+ L++ A DGG+P RS T ++ + I D NDNAP F +S+++  
Sbjct: 194 HIELILKKPFDRELMPSHELILTAIDGGTPQRSGTARINVRILDANDNAPVFGSSVYKVK 253

Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT-GNVDLPITIDPRSGWVYTSGQL 324
           +SEN P G  ++++ A D DEG N ++ Y+ +   YT   V    ++D  +G +     +
Sbjct: 254 LSENSPKGALVIKLNAADIDEGSNGDVFYSFS--SYTPERVRQMFSLDTDTGEIRVKNNI 311

Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
           D E    Y++ + A D G  P +A                  +       + ED    T 
Sbjct: 312 DYEETNSYEMYIQAMDKGPAPVAANCKVVVDILDVNDNVPEIVLSSLSSPVREDARADTV 371

Query: 385 VVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
           V  ++  D D  ++ ++  EI G N    F+I S      I  +  LD +  + Y +TVS
Sbjct: 372 VALISVNDRDSGQNKQVTLEI-GPNL--PFAIKSFRNHYTIVTSAFLDRETIKSYNVTVS 428

Query: 443 ATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
           A D G    S      +++ D N+  P FE   YT  V E+   G ++ VV ATD+D   
Sbjct: 429 AVDGGTPPLSSQMSFMVDVADVNDNPPRFEQTSYTVYVTENNAPGASLCVVRATDADAAE 488

Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560
           NA+ITY++ S+  N           I P TG     +  D E +  +   V A+D GVP 
Sbjct: 489 NARITYTVISD--NNYGIPVASYVSIKPNTGEAYALRAFDFEKLREFHFQVKAQDNGVPP 546

Query: 561 LSDTTDVEISVVDVNDNEP-VF----KQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615
           LS    V + ++D ND+ P +F       L T  +M++A  G  VS+V A D D G N  
Sbjct: 547 LSRVVTVYLYIMDQNDHVPKIFYPPTNGSLTTEMLMKNAEAGVLVSKVVAWDGDAGQNAW 606

Query: 616 IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675
           + Y L   + +   F +   +G IRT + +  ++  +  L  +  D G PP S+T  +HI
Sbjct: 607 LMYTLKQTNTDLDLFKVHEYTGEIRTTRHVIEDNSTSFVLTVLVRDHGLPPLSTTATLHI 666

Query: 676 KIEDINDSPPVFESDCLTFYISENSPI 702
            + ++   PP    D     I  NSP+
Sbjct: 667 HVMEL---PPKMTPDPKRI-IRPNSPL 689



 Score =  215 bits (524), Expect = 2e-53
 Identities = 156/500 (31%), Positives = 230/500 (46%), Gaps = 28/500 (5%)

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           + I DVNDNAP+F    +Q  VSE+   G       A DAD+G N+   Y ++  D+   
Sbjct: 124 VEILDVNDNAPQFPRDEYQLEVSESALTGTRFHIEGAQDADDGSNSVKQYRLSRNDHLTL 183

Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
             +    + +   +      DRE    ++L++TA DGG P RS TA              
Sbjct: 184 DSVKQFSNNKHIELILKKPFDRELMPSHELILTAIDGGTPQRSGTARINVRILDANDNAP 243

Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEI---TGGNTRGRFSITSQNG 419
            F    Y+V+L+E+ P G  V+ L A D DE +   + Y     T    R  FS+ +  G
Sbjct: 244 VFGSSVYKVKLSENSPKGALVIKLNAADIDEGSNGDVFYSFSSYTPERVRQMFSLDTDTG 303

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTAS 477
              I V   +D+++   Y + + A D G     A   V ++I D N+  P    +  ++ 
Sbjct: 304 E--IRVKNNIDYEETNSYEMYIQAMDKGPAPVAANCKVVVDILDVNDNVPEIVLSSLSSP 361

Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
           V EDA   T V ++S  D D G N Q+T  +   +     +  +   ++        T+ 
Sbjct: 362 VREDARADTVVALISVNDRDSGQNKQVTLEIGPNLPFAIKSFRNHYTIV--------TSA 413

Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
            LDRET+  Y +TV+A DGG P LS      + V DVNDN P F+Q  YT  + E+   G
Sbjct: 414 FLDRETIKSYNVTVSAVDGGTPPLSSQMSFMVDVADVNDNPPRFEQTSYTVYVTENNAPG 473

Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEG----SFV-IDPASGVIRTNKALDRESVAT 652
            S+  V ATDAD   N RI Y +   D   G    S+V I P +G     +A D E +  
Sbjct: 474 ASLCVVRATDADAAENARITYTV-ISDNNYGIPVASYVSIKPNTGEAYALRAFDFEKLRE 532

Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDS-PPVF----ESDCLTFYISENSPIGTTIG 707
              +  A D G PP S  V V++ I D ND  P +F         T  + +N+  G  + 
Sbjct: 533 FHFQVKAQDNGVPPLSRVVTVYLYIMDQNDHVPKIFYPPTNGSLTTEMLMKNAEAGVLVS 592

Query: 708 EIRAHDPDEGPNAVVHYSIK 727
           ++ A D D G NA + Y++K
Sbjct: 593 KVVAWDGDAGQNAWLMYTLK 612



 Score =  207 bits (506), Expect = 3e-51
 Identities = 160/587 (27%), Positives = 260/587 (44%), Gaps = 47/587 (8%)

Query: 4   PFCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
           P  +H  ++ +LD ND++P F   +Y+  V E A +GT      A D D G N+  +Y  
Sbjct: 116 PLDVHNVEVEILDVNDNAPQFPRDEYQLEVSESALTGTRFHIEGAQDADDGSNSVKQY-- 173

Query: 63  ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122
            L   D L  +                   + +   L+ +   DRE +  + +++ A D 
Sbjct: 174 RLSRNDHLTLDSVKQFS-------------NNKHIELILKKPFDRELMPSHELILTAIDG 220

Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
            +P   + S TA I+V I+D NDN P F    Y V + E  +     ++ K+ A D D G
Sbjct: 221 GTP---QRSGTARINVRILDANDNAPVFGSSVYKVKLSE--NSPKGALVIKLNAADIDEG 275

Query: 183 ANSAIRYAIIG---GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239
           +N  + Y+         +  FS+D+ +G++ +   +DYE+  SY + I+A D G    + 
Sbjct: 276 SNGDVFYSFSSYTPERVRQMFSLDTDTGEIRVKNNIDYEETNSYEMYIQAMDKGPAPVAA 335

Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
             +++++I DVNDN P    S     V E+      +  +   D D G N ++T      
Sbjct: 336 NCKVVVDILDVNDNVPEIVLSSLSSPVREDARADTVVALISVNDRDSGQNKQVTL----- 390

Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
           +   N+   I        + TS  LDRET   Y + V+A DGG PP S+  +        
Sbjct: 391 EIGPNLPFAIKSFRNHYTIVTSAFLDRETIKSYNVTVSAVDGGTPPLSSQMSFMVDVADV 450

Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRG---RFSI 414
                 F    Y V + E+  PG  +  + ATDAD  E+ R+ Y +   N  G      +
Sbjct: 451 NDNPPRFEQTSYTVYVTENNAPGASLCVVRATDADAAENARITYTVISDNNYGIPVASYV 510

Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENA 472
           + +   G     +  DF++ R +   V A D+G    S    V + I D N++ P     
Sbjct: 511 SIKPNTGEAYALRAFDFEKLREFHFQVKAQDNGVPPLSRVVTVYLYIMDQNDHVPKIFYP 570

Query: 473 PYTAS-----VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527
           P   S     + ++A  G  V  V A D D G NA + Y+L    +N  +      F ++
Sbjct: 571 PTNGSLTTEMLMKNAEAGVLVSKVVAWDGDAGQNAWLMYTLKQ--TNTDL----DLFKVH 624

Query: 528 PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
             TG I T + +  +  + ++LTV  RD G+P LS T  + I V+++
Sbjct: 625 EYTGEIRTTRHVIEDNSTSFVLTVLVRDHGLPPLSTTATLHIHVMEL 671



 Score =  180 bits (438), Expect = 5e-43
 Identities = 128/440 (29%), Positives = 214/440 (48%), Gaps = 23/440 (5%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRL--HYEITGGNTRGRFSIT--SQNGRG 421
           F   +Y++E++E    GT      A DAD+ +     Y ++  +     S+   S N   
Sbjct: 136 FPRDEYQLEVSESALTGTRFHIEGAQDADDGSNSVKQYRLSRNDHLTLDSVKQFSNNKHI 195

Query: 422 LITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVF 479
            + + +P D +    + L ++A D G   RS TA + + I DAN+ APVF ++ Y   + 
Sbjct: 196 ELILKKPFDRELMPSHELILTAIDGGTPQRSGTARINVRILDANDNAPVFGSSVYKVKLS 255

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           E++P G  V+ ++A D D G N  + YS SS  + E V    Q F ++  TG I     +
Sbjct: 256 ENSPKGALVIKLNAADIDEGSNGDVFYSFSS-YTPERVR---QMFSLDTDTGEIRVKNNI 311

Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
           D E  + Y + + A D G   ++    V + ++DVNDN P       ++ + EDA   T 
Sbjct: 312 DYEETNSYEMYIQAMDKGPAPVAANCKVVVDILDVNDNVPEIVLSSLSSPVREDARADTV 371

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG--VIRTNKALDRESVATHDLKA 657
           V+ +   D D G N ++  E+ P       F I        I T+  LDRE++ ++++  
Sbjct: 372 VALISVNDRDSGQNKQVTLEIGPNL----PFAIKSFRNHYTIVTSAFLDRETIKSYNVTV 427

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
            A+DGGTPP SS +   + + D+ND+PP FE    T Y++EN+  G ++  +RA D D  
Sbjct: 428 SAVDGGTPPLSSQMSFMVDVADVNDNPPRFEQTSYTVYVTENNAPGASLCVVRATDADAA 487

Query: 718 PNAVVHYSIKGGDDSNSFSLETRQG--SDKAELVTMVDLDYESPRKKYELVIRAAS---P 772
            NA + Y++   D++    + +      +  E   +   D+E  R+ +   ++A     P
Sbjct: 488 ENARITYTVIS-DNNYGIPVASYVSIKPNTGEAYALRAFDFEKLRE-FHFQVKAQDNGVP 545

Query: 773 PLWNDVRVEILVTDVNDNAP 792
           PL   V V + + D ND+ P
Sbjct: 546 PLSRVVTVYLYIMDQNDHVP 565



 Score =  159 bits (386), Expect = 1e-36
 Identities = 134/474 (28%), Positives = 210/474 (44%), Gaps = 23/474 (4%)

Query: 374 ELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGR-FSITSQNGRGLITVAQPLDFK 432
           EL    P G  V  L   D  + +     +T   T  R F+I  +NG+  +TV+  +D +
Sbjct: 40  ELENGAPVGDIVQDL-GLDPRKLSARRIRVTSDGTHRRYFAINHKNGK--LTVSDRIDRE 96

Query: 433 QERRYVLTVSATDS---GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
               +  T S           D   V++ I D N+ AP F    Y   V E A  GT   
Sbjct: 97  TICEFTGTCSLNLEVVLENPLDVHNVEVEILDVNDNAPQFPRDEYQLEVSESALTGTRFH 156

Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
           +  A D+D G N+   Y LS   ++       +QF  N     I   K  DRE M  + L
Sbjct: 157 IEGAQDADDGSNSVKQYRLSR--NDHLTLDSVKQFSNNKHIELIL-KKPFDRELMPSHEL 213

Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
            +TA DGG P  S T  + + ++D NDN PVF   +Y   + E++  G  V ++ A D D
Sbjct: 214 ILTAIDGGTPQRSGTARINVRILDANDNAPVFGSSVYKVKLSENSPKGALVIKLNAADID 273

Query: 610 VGLNGRIHYELDP--KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
            G NG + Y       +R    F +D  +G IR    +D E   ++++   A+D G  P 
Sbjct: 274 EGSNGDVFYSFSSYTPERVRQMFSLDTDTGEIRVKNNIDYEETNSYEMYIQAMDKGPAPV 333

Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
           ++   V + I D+ND+ P      L+  + E++   T +  I  +D D G N  V   I 
Sbjct: 334 AANCKVVVDILDVNDNVPEIVLSSLSSPVREDARADTVVALISVNDRDSGQNKQVTLEI- 392

Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILV 784
               +  F++++ +  +   +VT   LD E+  K Y + + A    +PPL + +   + V
Sbjct: 393 --GPNLPFAIKSFR--NHYTIVTSAFLDRETI-KSYNVTVSAVDGGTPPLSSQMSFMVDV 447

Query: 785 TDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGNN 836
            DVNDN P  +         ++  P      V A DAD  +  ++ Y ++S NN
Sbjct: 448 ADVNDNPPRFEQTSYTVYVTENNAPGASLCVVRATDADAAENARITYTVISDNN 501


>UniRef50_Q7PT49 Cluster: ENSANGP00000019477; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000019477 - Anopheles gambiae
           str. PEST
          Length = 976

 Score =  235 bits (574), Expect = 2e-59
 Identities = 242/811 (29%), Positives = 367/811 (45%), Gaps = 82/811 (10%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +I VLD ND  PVF  +    ++ E    GT V+ ++A D D G  A     I     D 
Sbjct: 218 KIKVLDENDIIPVFT-EVTSGTIPEDEPPGTPVMQVRAYDLD-GTPAN---NIVSYRFDD 272

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            N               Q +F ID R+G + +R   DRE    Y + + A D  SP +  
Sbjct: 273 EN---------------QQLFHIDSRTGNITSRVEFDREATDSYHLKIIAEDN-SPSA-- 314

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTV-SVDEDISVTDNPVIAKIKATDADVGANSAIR 188
           L S   I + I D ND+ P+F +  +   +V ED ++  N V+ ++ A D D    S I 
Sbjct: 315 LISQLFI-IKISDKNDHQPKFVKDHFVAENVPEDANI--NTVVIEVTALDQDTA--SLIT 369

Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
           Y+II GN    F ID  +G +S+   LDYE +R Y L+++A DG    + N T + I I 
Sbjct: 370 YSIIEGNVGDAFKIDENTGRISVNSRLDYETIREYMLIVQADDG--IFQDNAT-VSIKIE 426

Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYD-----ADEGVNAELTYTMTDKDYT- 302
           +VNDN PRF          E +P G  I+ +QAYD      DE  +   ++   DK  + 
Sbjct: 427 NVNDNPPRFIDLRNVTIQEETIPPG-CIMTIQAYDPDIENRDEPQHIRFSFEAVDKSGSI 485

Query: 303 --GNVDLPITIDPRSGWVYTSG---QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357
              NV     +    G + T     Q          + V ATD G P      T      
Sbjct: 486 RFHNVTAEEFVSRTPGQLTTPKDRLQASIANTLNIYITVRATDNGRPRLDDVCTFKVMIL 545

Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DNR-LHYEITGGNTRGRFSIT 415
                   F   +YE  + +D      V T++ATD D+ DN  + YEI   N    +   
Sbjct: 546 DINDNPPVFDKVRYEESVTKDMKANLRVATISATDMDDGDNSIIKYEIVQQNPDSSYFKI 605

Query: 416 SQNGRGLITVAQP-LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPY 474
           ++N  GL+T+ +P LD++    Y LTVS  +S       +++I + D N+  PVF     
Sbjct: 606 NEN-NGLLTLTKPTLDYETVTEYTLTVSVKNSYNNVVETVLKIKVLDENDIIPVFTEVT- 663

Query: 475 TASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
           + ++ E+ P GT V+ V A D D    N  ++Y +  E        + Q F I+ +TG+I
Sbjct: 664 SGTIPENEPPGTPVMQVRAYDLDGTPANNIVSYRIEDE--------NQQLFHIDSRTGSI 715

Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSL-------SDTTDVEISVVDVNDNEPVF-KQQL 585
           T+    DRE    Y L + A D    +L       S +    I + D ND++P F K  L
Sbjct: 716 TSRVEFDREATDSYHLKIIAEDNSPSALYSNGKPNSCSQLFTIKISDKNDHKPRFVKGLL 775

Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645
            T ++ ED+ +  ++ +V A D D      I Y +  +     +F ID  +G I  N  L
Sbjct: 776 ATEDVSEDSDINMTLIEVKALDQDTA--SLITYSI-IEGNVGDAFKIDEHTGRISINNWL 832

Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT- 704
           D E++  + L  V  D G    S+T  V+IKI+++ND+PP F          E  P G  
Sbjct: 833 DYETIREYKL-IVQADDGIFQDSTT--VYIKIKNVNDNPPRFTGIRNVTIQEETIPSGPP 889

Query: 705 -TIGEIRAHDPDEGPNA-VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762
             I  + A D DE  N    H+SI   D +  + ++ R      EL  +V+ D E  +K+
Sbjct: 890 GLIVRLTAEDVDEAQNGPPFHFSI---DPNAPYEIKERFQVQNDELYALVEFDREE-QKE 945

Query: 763 YELVIR---AASPPLWNDVRVEILVTDVNDN 790
           Y + IR   +   P+ +   +++++ D NDN
Sbjct: 946 YRVPIRISDSGEEPMSDVSILQLVIGDDNDN 976



 Score =  226 bits (553), Expect = 6e-57
 Identities = 236/903 (26%), Positives = 401/903 (44%), Gaps = 91/903 (10%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ +LD ND+ PVF+  +YE SV +   +   V T+ ATD D G N+ ++Y  E+V    
Sbjct: 32  KVTILDINDNPPVFDKVRYEESVTKDMKANLRVATISATDMDDGDNSIIKY--EIVQQ-- 87

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            NP+ +              F+I+  +G L     +DR     Y++ V+A +        
Sbjct: 88  -NPDSSY-------------FKINENNGLLTLTKPVDRSPGQYYSIRVRAYN-------- 125

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
                      +D      Q +E    V V E   +   P   K++A  A +  N   + 
Sbjct: 126 -----------VDPQGEAVQDAEVDVKVRVVESNKLP--PYFTKVQA--AALVLNETFK- 169

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
                 T+     ++ S      +TLDYE V  Y L +  ++  S      T L I + D
Sbjct: 170 ----NYTESLAEFEAESNIPEKPETLDYETVTEYTLTVSVKN--SHDLVAETVLKIKVLD 223

Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYTGNVDLP 308
            ND  P F T +   ++ E+ P G  +++V+AYD D    N  ++Y   D+    N  L 
Sbjct: 224 ENDIIPVF-TEVTSGTIPEDEPPGTPVMQVRAYDLDGTPANNIVSYRFDDE----NQQL- 277

Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
             ID R+G + +  + DRE    Y L + A D   P    +                F+ 
Sbjct: 278 FHIDSRTGNITSRVEFDREATDSYHLKIIAEDNS-PSALISQLFIIKISDKNDHQPKFVK 336

Query: 369 GQYEVE-LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
             +  E + ED    T V+ +TA D D  + + Y I  GN    F I    GR  I+V  
Sbjct: 337 DHFVAENVPEDANINTVVIEVTALDQDTASLITYSIIEGNVGDAFKIDENTGR--ISVNS 394

Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
            LD++  R Y+L V A D G   D A V I I + N+  P F +        E  P G  
Sbjct: 395 RLDYETIREYMLIVQA-DDGIFQDNATVSIKIENVNDNPPRFIDLRNVTIQEETIPPGC- 452

Query: 488 VLVVSATDSDVGINAQ---ITYSLSSEISNEAVAHHD---QQFVINPQTGAITTNKLLDR 541
           ++ + A D D+    +   I +S  +   + ++  H+   ++FV +   G +TT K   +
Sbjct: 453 IMTIQAYDPDIENRDEPQHIRFSFEAVDKSGSIRFHNVTAEEFV-SRTPGQLTTPKDRLQ 511

Query: 542 ETMSGYL---LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            +++  L   +TV A D G P L D    ++ ++D+NDN PVF +  Y  ++ +D     
Sbjct: 512 ASIANTLNIYITVRATDNGRPRLDDVCTFKVMILDINDNPPVFDKVRYEESVTKDMKANL 571

Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR-TNKALDRESVATHDLKA 657
            V+ + ATD D G N  I YE+  ++ +   F I+  +G++  T   LD E+V  + L  
Sbjct: 572 RVATISATDMDDGDNSIIKYEIVQQNPDSSYFKINENNGLLTLTKPTLDYETVTEYTL-T 630

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
           V++         TV+  IK+ D ND  PVF ++  +  I EN P GT + ++RA+D D  
Sbjct: 631 VSVKNSYNNVVETVL-KIKVLDENDIIPVF-TEVTSGTIPENEPPGTPVMQVRAYDLDGT 688

Query: 718 P-NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP--L 774
           P N +V Y I+  ++   F +++R GS    + + V+ D E+    +  +I   + P  L
Sbjct: 689 PANNIVSYRIE-DENQQLFHIDSRTGS----ITSRVEFDREATDSYHLKIIAEDNSPSAL 743

Query: 775 WNDVR-------VEILVTDVNDNAP-VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK 826
           +++ +         I ++D ND+ P  +K      +  +D         V A D D    
Sbjct: 744 YSNGKPNSCSQLFTIKISDKNDHKPRFVKGLLATEDVSEDSDINMTLIEVKALDQDTASL 803

Query: 827 LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886
           + Y I+ GN  +   ++E TG ++++  L+    +   + V   DG+ +    + + ++ 
Sbjct: 804 ITYSIIEGNVGDAFKIDEHTGRISINNWLDYETIREYKLIVQADDGIFQDSTTVYIKIKN 863

Query: 887 ITE 889
           + +
Sbjct: 864 VND 866



 Score =  226 bits (552), Expect = 8e-57
 Identities = 223/754 (29%), Positives = 351/754 (46%), Gaps = 68/754 (9%)

Query: 104 SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI 163
           +LD E V  YT+ V   +     S  L +   + + ++D+ND  P F+E T + ++ ED 
Sbjct: 190 TLDYETVTEYTLTVSVKN-----SHDLVAETVLKIKVLDENDIIPVFTEVT-SGTIPED- 242

Query: 164 SVTDNPVIAKIKATDAD-VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222
                PV+ +++A D D   AN+ + Y     N Q+ F IDS +G+++     D E   S
Sbjct: 243 EPPGTPVM-QVRAYDLDGTPANNIVSYRFDDENQQL-FHIDSRTGNITSRVEFDREATDS 300

Query: 223 YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLF-QESVSENVPIGYSIVRVQA 281
           Y L I A+D  SPS   +   +I I D ND+ P+F    F  E+V E+  I   ++ V A
Sbjct: 301 YHLKIIAEDN-SPSALISQLFIIKISDKNDHQPKFVKDHFVAENVPEDANINTVVIEVTA 359

Query: 282 YDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341
            D D    + +TY++ +    GNV     ID  +G +  + +LD ET  +Y L+V A DG
Sbjct: 360 LDQDTA--SLITYSIIE----GNVGDAFKIDENTGRISVNSRLDYETIREYMLIVQADDG 413

Query: 342 GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--- 398
                   AT              F+  +      E  PPG  ++T+ A D D +NR   
Sbjct: 414 ---IFQDNATVSIKIENVNDNPPRFIDLRNVTIQEETIPPGC-IMTIQAYDPDIENRDEP 469

Query: 399 ----LHYEITGGNTRGRF-SITSQN--GRGLITVAQPLDFKQER-----RYVLTVSATDS 446
                 +E    +   RF ++T++    R    +  P D  Q          +TV ATD+
Sbjct: 470 QHIRFSFEAVDKSGSIRFHNVTAEEFVSRTPGQLTTPKDRLQASIANTLNIYITVRATDN 529

Query: 447 GGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504
           G     D    ++ I D N+  PVF+   Y  SV +D      V  +SATD D G N+ I
Sbjct: 530 GRPRLDDVCTFKVMILDINDNPPVFDKVRYEESVTKDMKANLRVATISATDMDDGDNSII 589

Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTGAITTNK-LLDRETMSGYLLTVTARDGGVPSLSD 563
            Y +  +  + +       F IN   G +T  K  LD ET++ Y LTV+ ++    ++ +
Sbjct: 590 KYEIVQQNPDSSY------FKINENNGLLTLTKPTLDYETVTEYTLTVSVKNS-YNNVVE 642

Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDP 622
           T  ++I V+D ND  PVF + + +  I E+   GT V QV A D D    N  + Y ++ 
Sbjct: 643 TV-LKIKVLDENDIIPVFTE-VTSGTIPENEPPGTPVMQVRAYDLDGTPANNIVSYRIE- 699

Query: 623 KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP-------PQSSTVIVHI 675
            D  +  F ID  +G I +    DRE+  ++ LK +A D           P S + +  I
Sbjct: 700 -DENQQLFHIDSRTGSITSRVEFDREATDSYHLKIIAEDNSPSALYSNGKPNSCSQLFTI 758

Query: 676 KIEDINDSPPVFESDCL-TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734
           KI D ND  P F    L T  +SE+S I  T+ E++A D D    +++ YSI  G+  ++
Sbjct: 759 KISDKNDHKPRFVKGLLATEDVSEDSDINMTLIEVKALDQDTA--SLITYSIIEGNVGDA 816

Query: 735 FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVM 794
           F ++   G     +     LDYE+ R+ Y+L+++A      +   V I + +VNDN P  
Sbjct: 817 FKIDEHTG----RISINNWLDYETIRE-YKLIVQADDGIFQDSTTVYIKIKNVNDNPPRF 871

Query: 795 KDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQ 828
              + +    ++  P GP G +    A+  D+ Q
Sbjct: 872 TGIRNV-TIQEETIPSGPPGLIVRLTAEDVDEAQ 904



 Score =  178 bits (434), Expect = 2e-42
 Identities = 216/767 (28%), Positives = 322/767 (41%), Gaps = 94/767 (12%)

Query: 115 VLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKI 174
           + V+ATD   P   RL    T  V I+D NDN P F +  Y  SV +D+    N  +A I
Sbjct: 13  ITVRATDNGRP---RLDDVCTFKVTILDINDNPPVFDKVRYEESVTKDMKA--NLRVATI 67

Query: 175 KATDADVGANSAIRYAIIGGNTQMQ-FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233
            ATD D G NS I+Y I+  N     F I+  +G ++L K +D    + Y + +RA +  
Sbjct: 68  SATDMDDGDNSIIKYEIVQQNPDSSYFKINENNGLLTLTKPVDRSPGQYYSIRVRAYNVD 127

Query: 234 SPSRS-NTTQLLINIRDVNDN-APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE 291
               +    ++ + +R V  N  P ++T                  +VQA        A 
Sbjct: 128 PQGEAVQDAEVDVKVRVVESNKLPPYFT------------------KVQA--------AA 161

Query: 292 LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
           L    T K+YT ++      +  S        LD ET  +Y L V+  +  D       T
Sbjct: 162 LVLNETFKNYTESL---AEFEAESNIPEKPETLDYETVTEYTLTVSVKNSHD---LVAET 215

Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNT 408
                                  + EDEPPGTPV+ + A D D    +N + Y     N 
Sbjct: 216 VLKIKVLDENDIIPVFTEVTSGTIPEDEPPGTPVMQVRAYDLDGTPANNIVSYRFDDENQ 275

Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD-SGGRSDTAMVQINITDANNYAP 467
           +  F I S+ G   IT     D +    Y L + A D S     + +  I I+D N++ P
Sbjct: 276 Q-LFHIDSRTGN--ITSRVEFDREATDSYHLKIIAEDNSPSALISQLFIIKISDKNDHQP 332

Query: 468 VFENAPYTA-SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
            F    + A +V EDA I T V+ V+A D D    + ITYS+      +A       F I
Sbjct: 333 KFVKDHFVAENVPEDANINTVVIEVTALDQDTA--SLITYSIIEGNVGDA-------FKI 383

Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586
           +  TG I+ N  LD ET+  Y+L V A DG      D   V I + +VNDN P F   L 
Sbjct: 384 DENTGRISVNSRLDYETIREYMLIVQADDG---IFQDNATVSIKIENVNDNPPRF-IDLR 439

Query: 587 TANIMEDALVGTSVSQVGATDADVGLNG---RIHYELDPKDREEGSF---------VIDP 634
              I E+ +    +  + A D D+        I +  +  D+  GS           +  
Sbjct: 440 NVTIQEETIPPGCIMTIQAYDPDIENRDEPQHIRFSFEAVDK-SGSIRFHNVTAEEFVSR 498

Query: 635 ASGVIRTNKALDRESVATH---DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691
             G + T K   + S+A      +   A D G P         + I DIND+PPVF+   
Sbjct: 499 TPGQLTTPKDRLQASIANTLNIYITVRATDNGRPRLDDVCTFKVMILDINDNPPVFDKVR 558

Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-KGGDDSNSFSLETRQGSDKAELVT 750
               ++++      +  I A D D+G N+++ Y I +   DS+ F +    G      +T
Sbjct: 559 YEESVTKDMKANLRVATISATDMDDGDNSIIKYEIVQQNPDSSYFKINENNG---LLTLT 615

Query: 751 MVDLDYESPRKKYELVIRAASPPLWNDV---RVEILVTDVNDNAPVMKDFQIIFNNYKDC 807
              LDYE+   +Y L +   +   +N+V    ++I V D ND  PV    ++      + 
Sbjct: 616 KPTLDYETV-TEYTLTVSVKNS--YNNVVETVLKIKVLDENDIIPVFT--EVTSGTIPEN 670

Query: 808 FPVG-PFGRVPAYDADVT---DKLQYRILSGNNANLILLNETTGSMT 850
            P G P  +V AYD D T   + + YRI    N  L  ++  TGS+T
Sbjct: 671 EPPGTPVMQVRAYDLDGTPANNIVSYRI-EDENQQLFHIDSRTGSIT 716



 Score = 65.7 bits (153), Expect = 2e-08
 Identities = 49/166 (29%), Positives = 76/166 (45%), Gaps = 11/166 (6%)

Query: 433 QERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
           +E+   +TV ATD+G     D    ++ I D N+  PVF+   Y  SV +D      V  
Sbjct: 7   REKEIYITVRATDNGRPRLDDVCTFKVTILDINDNPPVFDKVRYEESVTKDMKANLRVAT 66

Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550
           +SATD D G N+ I Y +  +  + +       F IN   G +T  K +DR     Y + 
Sbjct: 67  ISATDMDDGDNSIIKYEIVQQNPDSS------YFKINENNGLLTLTKPVDRSPGQYYSIR 120

Query: 551 VTAR--DGGVPSLSDT-TDVEISVVDVNDNEPVFKQQLYTANIMED 593
           V A   D    ++ D   DV++ VV+ N   P F +    A ++ +
Sbjct: 121 VRAYNVDPQGEAVQDAEVDVKVRVVESNKLPPYFTKVQAAALVLNE 166


>UniRef50_Q17NI9 Cluster: Protocadherin; n=3; Endopterygota|Rep:
           Protocadherin - Aedes aegypti (Yellowfever mosquito)
          Length = 605

 Score =  234 bits (573), Expect = 2e-59
 Identities = 173/533 (32%), Positives = 258/533 (48%), Gaps = 45/533 (8%)

Query: 92  IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151
           ID  +G + T+  LDREK A Y+++      A P+S        + + ++D+NDN P F 
Sbjct: 95  IDHTTGEIRTKVLLDREKRASYSLV------AIPLS---GENVRVVIRVLDENDNAPTFP 145

Query: 152 EKTYTVSVDE----DISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS--- 204
                +   E    D+  T NP      A D D+G  +  RY I+ GN    F + S   
Sbjct: 146 TALMNIEFPENTPRDVKRTLNP------ARDLDLGRYNTQRYNIVSGNVNNAFRLSSHRE 199

Query: 205 ----LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260
               L  D+ +   LD E   +Y LV+ A DGG+P       + I I+DVNDN P F  S
Sbjct: 200 RDGVLYLDLQINGFLDRETTPAYSLVVEALDGGNPPLRGQMTVNITIQDVNDNQPIFNQS 259

Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT 320
            +  +V EN  IG ++++V A D D G N  + Y +  +    + D    IDP +G +  
Sbjct: 260 RYFATVPENATIGTTVLQVYATDQDAGENGMVEYAINRRQ--SDKDQMFRIDPNTGLISV 317

Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX----XXFMPGQYEVELA 376
           +  LD ET+  ++L+V A D G  P   TA                   F+      +++
Sbjct: 318 NKPLDFETKELHELVVVAKDRGLQPLETTAFVSIRVTDVNDNQPIINVIFLSDDATPKIS 377

Query: 377 EDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQ-NGRGLITVAQPLDFK 432
           E   PG  V  ++  D D   E + ++  ++GG   G F +T++ N   L+ V+ PLD +
Sbjct: 378 ESAQPGEFVARISVNDPDSKTEYSNVNVTLSGGE--GHFGLTTRDNIIYLVIVSLPLDRE 435

Query: 433 QERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
            +  Y L+V ATD+G     A   + + +TD N+ AP FE   Y A+V E A  GT+V+ 
Sbjct: 436 IKPNYTLSVVATDTGNPPLHAAKTIFLTVTDINDNAPEFEKEIYHANVMEVADPGTSVIQ 495

Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550
           V+A D D G N+ I YSL           H Q F I+  +G ITT   +D ET     L 
Sbjct: 496 VTAIDKDEGNNSAIAYSLLDTPDT-----HSQWFQIDSNSGLITTRAHIDCETDPVPQLI 550

Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
           V A+D G P +S T  V +++ DVNDNEP+F Q  Y  ++ E+   G  + +V
Sbjct: 551 VVAKDNGFPPMSSTGTVLVTIHDVNDNEPIFDQSFYNVSVAENEPKGRCILKV 603



 Score =  221 bits (541), Expect = 2e-55
 Identities = 174/545 (31%), Positives = 242/545 (44%), Gaps = 36/545 (6%)

Query: 182 GANSAIRYAII---GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238
           G +S   Y I+   G       +ID  +G++     LD E+  SY LV        P   
Sbjct: 72  GVDSGPPYLIVPVPGSAVDTDLAIDHTTGEIRTKVLLDREKRASYSLV------AIPLSG 125

Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
              +++I + D NDNAP F T+L      EN P         A D D G      Y +  
Sbjct: 126 ENVRVVIRVLDENDNAPTFPTALMNIEFPENTPRDVKRTLNPARDLDLGRYNTQRYNIV- 184

Query: 299 KDYTGNVDLPITIDP---RSGWVYT----SGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
              +GNV+    +     R G +Y     +G LDRET   Y L+V A DGG+PP     T
Sbjct: 185 ---SGNVNNAFRLSSHRERDGVLYLDLQINGFLDRETTPAYSLVVEALDGGNPPLRGQMT 241

Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTR 409
                         F   +Y   + E+   GT V+ + ATD D  E+  + Y I    + 
Sbjct: 242 VNITIQDVNDNQPIFNQSRYFATVPENATIGTTVLQVYATDQDAGENGMVEYAINRRQSD 301

Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAP 467
                      GLI+V +PLDF+ +  + L V A D G +    TA V I +TD N+  P
Sbjct: 302 KDQMFRIDPNTGLISVNKPLDFETKELHELVVVAKDRGLQPLETTAFVSIRVTDVNDNQP 361

Query: 468 V----FENAPYTASVFEDAPIGTTVLVVSATDSDVGIN-AQITYSLSSEISNEAVAHHDQ 522
           +    F +   T  + E A  G  V  +S  D D     + +  +LS    +  +   D 
Sbjct: 362 IINVIFLSDDATPKISESAQPGEFVARISVNDPDSKTEYSNVNVTLSGGEGHFGLTTRDN 421

Query: 523 QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582
              +      +  +  LDRE    Y L+V A D G P L     + ++V D+NDN P F+
Sbjct: 422 IIYL------VIVSLPLDREIKPNYTLSVVATDTGNPPLHAAKTIFLTVTDINDNAPEFE 475

Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGVIRT 641
           +++Y AN+ME A  GTSV QV A D D G N  I Y  LD  D     F ID  SG+I T
Sbjct: 476 KEIYHANVMEVADPGTSVIQVTAIDKDEGNNSAIAYSLLDTPDTHSQWFQIDSNSGLITT 535

Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701
              +D E+     L  VA D G PP SST  V + I D+ND+ P+F+       ++EN P
Sbjct: 536 RAHIDCETDPVPQLIVVAKDNGFPPMSSTGTVLVTIHDVNDNEPIFDQSFYNVSVAENEP 595

Query: 702 IGTTI 706
            G  I
Sbjct: 596 KGRCI 600



 Score =  206 bits (503), Expect = 7e-51
 Identities = 164/546 (30%), Positives = 246/546 (45%), Gaps = 36/546 (6%)

Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325
           VSE VPIG+ I  +  +    GV++   Y +     +  VD  + ID  +G + T   LD
Sbjct: 53  VSEGVPIGHQIGFIGEFL--HGVDSGPPYLIVPVPGSA-VDTDLAIDHTTGEIRTKVLLD 109

Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
           RE +A Y L+     G +                      F      +E  E+ P     
Sbjct: 110 REKRASYSLVAIPLSGEN------VRVVIRVLDENDNAPTFPTALMNIEFPENTPRDVKR 163

Query: 386 VTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGR-GLITVAQP----LDFKQERRYV 438
               A D D    N   Y I  GN    F ++S   R G++ +       LD +    Y 
Sbjct: 164 TLNPARDLDLGRYNTQRYNIVSGNVNNAFRLSSHRERDGVLYLDLQINGFLDRETTPAYS 223

Query: 439 LTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496
           L V A D G       + +NIT  D N+  P+F  + Y A+V E+A IGTTVL V ATD 
Sbjct: 224 LVVEALDGGNPPLRGQMTVNITIQDVNDNQPIFNQSRYFATVPENATIGTTVLQVYATDQ 283

Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556
           D G N  + Y+++   S++     DQ F I+P TG I+ NK LD ET   + L V A+D 
Sbjct: 284 DAGENGMVEYAINRRQSDK-----DQMFRIDPNTGLISVNKPLDFETKELHELVVVAKDR 338

Query: 557 GVPSLSDTTDVEISVVDVNDNEPV----FKQQLYTANIMEDALVGTSVSQVGATDADVGL 612
           G+  L  T  V I V DVNDN+P+    F     T  I E A  G  V+++   D D   
Sbjct: 339 GLQPLETTAFVSIRVTDVNDNQPIINVIFLSDDATPKISESAQPGEFVARISVNDPDSKT 398

Query: 613 N-GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671
               ++  L   +   G    D    ++  +  LDRE    + L  VA D G PP  +  
Sbjct: 399 EYSNVNVTLSGGEGHFGLTTRDNIIYLVIVSLPLDREIKPNYTLSVVATDTGNPPLHAAK 458

Query: 672 IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD 731
            + + + DIND+ P FE +     + E +  GT++ ++ A D DEG N+ + YS+    D
Sbjct: 459 TIFLTVTDINDNAPEFEKEIYHANVMEVADPGTSVIQVTAIDKDEGNNSAIAYSLLDTPD 518

Query: 732 SNS--FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--PPLWNDVRVEILVTDV 787
           ++S  F +++  G     + T   +D E+      +V+   +  PP+ +   V + + DV
Sbjct: 519 THSQWFQIDSNSGL----ITTRAHIDCETDPVPQLIVVAKDNGFPPMSSTGTVLVTIHDV 574

Query: 788 NDNAPV 793
           NDN P+
Sbjct: 575 NDNEPI 580



 Score =  162 bits (394), Expect = 1e-37
 Identities = 143/494 (28%), Positives = 212/494 (42%), Gaps = 33/494 (6%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I VLD ND++P F          E            A D D+G+     Y I  V+ +  
Sbjct: 132 IRVLDENDNAPTFPTALMNIEFPENTPRDVKRTLNPARDLDLGRYNTQRYNI--VSGNVN 189

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           N                D+ +I+G          LDRE    Y+++V+A D  +P    L
Sbjct: 190 NAFRLSSHRERDGVLYLDL-QING---------FLDRETTPAYSLVVEALDGGNPP---L 236

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
               T+++ I D NDN P F++  Y  +V E+ ++     + ++ ATD D G N  + YA
Sbjct: 237 RGQMTVNITIQDVNDNQPIFNQSRYFATVPENATI--GTTVLQVYATDQDAGENGMVEYA 294

Query: 191 IIG--GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
           I     +    F ID  +G +S+ K LD+E    + LV+ A+D G      T  + I + 
Sbjct: 295 INRRQSDKDQMFRIDPNTGLISVNKPLDFETKELHELVVVAKDRGLQPLETTAFVSIRVT 354

Query: 249 DVNDNAPRFYTSLFQES----VSENVPIGYSIVRVQAYDADEGVN-AELTYTMTDKDYTG 303
           DVNDN P        +     +SE+   G  + R+   D D     + +  T++  +  G
Sbjct: 355 DVNDNQPIINVIFLSDDATPKISESAQPGEFVARISVNDPDSKTEYSNVNVTLSGGE--G 412

Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
           +  L  T D     V  S  LDRE +  Y L V ATD G+PP  A  T            
Sbjct: 413 HFGLT-TRDNIIYLVIVSLPLDREIKPNYTLSVVATDTGNPPLHAAKTIFLTVTDINDNA 471

Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGG-NTRGRFSITSQNGR 420
             F    Y   + E   PGT V+ +TA D DE N   + Y +    +T  ++     N  
Sbjct: 472 PEFEKEIYHANVMEVADPGTSVIQVTAIDKDEGNNSAIAYSLLDTPDTHSQWFQIDSNS- 530

Query: 421 GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASV 478
           GLIT    +D + +    L V A D+G    S T  V + I D N+  P+F+ + Y  SV
Sbjct: 531 GLITTRAHIDCETDPVPQLIVVAKDNGFPPMSSTGTVLVTIHDVNDNEPIFDQSFYNVSV 590

Query: 479 FEDAPIGTTVLVVS 492
            E+ P G  +L VS
Sbjct: 591 AENEPKGRCILKVS 604



 Score =  118 bits (285), Expect = 2e-24
 Identities = 89/290 (30%), Positives = 134/290 (46%), Gaps = 32/290 (11%)

Query: 521 DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580
           D    I+  TG I T  LLDRE  + Y L        +P   +   V I V+D NDN P 
Sbjct: 90  DTDLAIDHTTGEIRTKVLLDREKRASYSLVA------IPLSGENVRVVIRVLDENDNAPT 143

Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVG---------LNGRIH--YELDPKDREEGS 629
           F   L      E+       +   A D D+G         ++G ++  + L      +G 
Sbjct: 144 FPTALMNIEFPENTPRDVKRTLNPARDLDLGRYNTQRYNIVSGNVNNAFRLSSHRERDGV 203

Query: 630 FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES 689
             +D     ++ N  LDRE+   + L   A+DGG PP    + V+I I+D+ND+ P+F  
Sbjct: 204 LYLD-----LQINGFLDRETTPAYSLVVEALDGGNPPLRGQMTVNITIQDVNDNQPIFNQ 258

Query: 690 DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI--KGGDDSNSFSLETRQGSDKAE 747
                 + EN+ IGTT+ ++ A D D G N +V Y+I  +  D    F ++   G     
Sbjct: 259 SRYFATVPENATIGTTVLQVYATDQDAGENGMVEYAINRRQSDKDQMFRIDPNTGL---- 314

Query: 748 LVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVM 794
           +     LD+E+ ++ +ELV+ A      PL     V I VTDVNDN P++
Sbjct: 315 ISVNKPLDFET-KELHELVVVAKDRGLQPLETTAFVSIRVTDVNDNQPII 363


>UniRef50_Q4SJS0 Cluster: Chromosome 1 SCAF14573, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 1
           SCAF14573, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 734

 Score =  234 bits (572), Expect = 3e-59
 Identities = 197/706 (27%), Positives = 318/706 (45%), Gaps = 43/706 (6%)

Query: 100 LTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSV 159
           L R +L  E+      ++  T    P  D +     I     D NDN P F +    + V
Sbjct: 51  LDREALCPEETEAERCIILLTAVVGPSGDLIQFPVIIE----DVNDNEPYFEKSEIHLWV 106

Query: 160 DEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLV--KTLDY 217
            ED +V  + ++  ++A D D G NS + Y +   N     +       +SLV    LD 
Sbjct: 107 SEDATVGTS-LLLDVQAVDRDAGRNSEVHYRLEDPNGVFGLTFKEDGPIISLVVQTALDR 165

Query: 218 EQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE-SVSENVPIGYSI 276
           E    Y + + A D GS   S T  L++ + DV+DN P F     +  ++  + P    +
Sbjct: 166 ETRDFYEVKLEAADCGSNPLSATATLIVTVTDVDDNCPSFSPDNPRSVTIPGDSPRSMLV 225

Query: 277 VRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLV 336
            +V+A D D   NA + Y+++ K  +       ++D  +G +  +  L  +T  +  L V
Sbjct: 226 AQVRAIDPDSATNAAIIYSLSPK-VSERAKKLFSLDSLTGDIRLAQDLHSDTSEELLLKV 284

Query: 337 TATDGGDPPRSATATXXXXXXXXXXXXXXF-MPGQYEVELAEDEPPGTPVVTLTATDADE 395
            A+    PP     T                  G+++ + A   P   P   L   + + 
Sbjct: 285 LASSQHCPPADTLVTVSILPKAYRELMIKIAFIGEHQ-KGAMVLPENQPPTALAILELEG 343

Query: 396 DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV-----SATDSGGRS 450
           DN           +  FS++ QNG+ L++ ++PLD + +  Y + V     SA  S    
Sbjct: 344 DNSFISSSLTIENKVPFSLSPQNGKYLLSTSKPLDHEMKSDYSIGVVARGTSADGSASAP 403

Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510
              ++++ + D N+ AP F  + Y   V E+   G T+L VSA+D+D G N ++TY L +
Sbjct: 404 SRHILRVMVADVNDNAPNFLRSHYQLEVEENNRPGMTLLHVSASDADGGCNGRVTYRLGN 463

Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570
                   H    F ++P TG ++ +  LDRE  + +L+ V ARD G P L     V + 
Sbjct: 464 --------HTSTVFSVHPVTGRLSASTSLDREQQAAHLIRVFARDSGSPPLESAATVSVR 515

Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630
           V+D NDN PVF    +   + ED  + T V  V  +D D G NG +  EL  K+   G F
Sbjct: 516 VLDQNDNAPVFVTPHFIFFVPEDVPLFTEVGAVSVSDPDEGDNGNM--ELFFKN-NGGPF 572

Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPVF-- 687
            ++   G++ T   LD E    ++L  +A D G P   +ST  V I + D+ND+PP    
Sbjct: 573 CVNSTQGILHTTTNLDHEIEQRYELYLLASDRGYPSALTSTSRVTIFVVDVNDNPPKVIL 632

Query: 688 ---ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS---FSLETRQ 741
               S CLT  +  ++  GT + +I A D D G N+ V Y++   + + S   F +++R 
Sbjct: 633 PSSNSSCLT--VPADTIAGTVVTKIHAIDEDSGLNSEVTYTVVAPEPARSTAVFKVDSRS 690

Query: 742 GS-DKAELVTMVDLDYESPRKKYELVIRAASP-PLWNDVRVEILVT 785
           G+   AE +   DL        + +V     P PL+  V V +LV+
Sbjct: 691 GNITTAEQLLQKDL---GMHHLFVVVRDQGKPIPLYTTVWVNLLVS 733



 Score =  205 bits (501), Expect = 1e-50
 Identities = 198/689 (28%), Positives = 319/689 (46%), Gaps = 71/689 (10%)

Query: 15  DCNDHSPVFEMQQYEASVREGASSGTTVLT-LKATDQDIGKNAEVEYTIELVTADTLNPE 73
           D ND+ P FE  +    V E A+ GT++L  ++A D+D G+N+EV Y +E       +P 
Sbjct: 89  DVNDNEPYFEKSEIHLWVSEDATVGTSLLLDVQAVDRDAGRNSEVHYRLE-------DPN 141

Query: 74  DAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSST 133
                           F+ DG   +L+ + +LDRE    Y V ++A D     S+ LS+T
Sbjct: 142 GVFGL----------TFKEDGPIISLVVQTALDRETRDFYEVKLEAADCG---SNPLSAT 188

Query: 134 ATIHVNIIDDNDNYPQFS-EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI- 191
           AT+ V + D +DN P FS +   +V++  D     + ++A+++A D D   N+AI Y++ 
Sbjct: 189 ATLIVTVTDVDDNCPSFSPDNPRSVTIPGD--SPRSMLVAQVRAIDPDSATNAAIIYSLS 246

Query: 192 --IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             +    +  FS+DSL+GD+ L + L  +      L + A     P     T + ++I  
Sbjct: 247 PKVSERAKKLFSLDSLTGDIRLAQDLHSDTSEELLLKVLASSQHCPPAD--TLVTVSI-- 302

Query: 250 VNDNAPRFYTSLFQE--SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
                P+ Y  L  +   + E+      +   Q   A   +  E   +      T    +
Sbjct: 303 ----LPKAYRELMIKIAFIGEHQKGAMVLPENQPPTALAILELEGDNSFISSSLTIENKV 358

Query: 308 PITIDPRSG--WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX----XXXXXXXXX 361
           P ++ P++G   + TS  LD E ++ Y + V A  G     SA+A               
Sbjct: 359 PFSLSPQNGKYLLSTSKPLDHEMKSDYSIGVVAR-GTSADGSASAPSRHILRVMVADVND 417

Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNG 419
               F+   Y++E+ E+  PG  ++ ++A+DAD   + R+ Y + G +T   FS+    G
Sbjct: 418 NAPNFLRSHYQLEVEENNRPGMTLLHVSASDADGGCNGRVTYRL-GNHTSTVFSVHPVTG 476

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTAS 477
           R  ++ +  LD +Q+  +++ V A DSG       A V + + D N+ APVF    +   
Sbjct: 477 R--LSASTSLDREQQAAHLIRVFARDSGSPPLESAATVSVRVLDQNDNAPVFVTPHFIFF 534

Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
           V ED P+ T V  VS +D D G N  +              ++   F +N   G + T  
Sbjct: 535 VPEDVPLFTEVGAVSVSDPDEGDNGNMELFFK---------NNGGPFCVNSTQGILHTTT 585

Query: 538 LLDRETMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTAN-----IM 591
            LD E    Y L + A D G PS L+ T+ V I VVDVNDN P  K  L ++N     + 
Sbjct: 586 NLDHEIEQRYELYLLASDRGYPSALTSTSRVTIFVVDVNDNPP--KVILPSSNSSCLTVP 643

Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKD--REEGSFVIDPASGVIRTNKALDRES 649
            D + GT V+++ A D D GLN  + Y +   +  R    F +D  SG I T + L ++ 
Sbjct: 644 ADTIAGTVVTKIHAIDEDSGLNSEVTYTVVAPEPARSTAVFKVDSRSGNITTAEQLLQKD 703

Query: 650 VATHDLKAVAIDGGTP-PQSSTVIVHIKI 677
           +  H L  V  D G P P  +TV V++ +
Sbjct: 704 LGMHHLFVVVRDQGKPIPLYTTVWVNLLV 732



 Score =  197 bits (480), Expect = 4e-48
 Identities = 173/591 (29%), Positives = 262/591 (44%), Gaps = 37/591 (6%)

Query: 218 EQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277
           E+  + R +I       PS  +  Q  + I DVNDN P F  S     VSE+  +G S++
Sbjct: 59  EETEAERCIILLTAVVGPS-GDLIQFPVIIEDVNDNEPYFEKSEIHLWVSEDATVGTSLL 117

Query: 278 R-VQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLV 336
             VQA D D G N+E+ Y + D +  G   L    D     +     LDRET+  Y++ +
Sbjct: 118 LDVQAVDRDAGRNSEVHYRLEDPN--GVFGLTFKEDGPIISLVVQTALDRETRDFYEVKL 175

Query: 337 TATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ-YEVELAEDEPPGTPVVTLTATDADE 395
            A D G  P SATAT              F P     V +  D P    V  + A D D 
Sbjct: 176 EAADCGSNPLSATATLIVTVTDVDDNCPSFSPDNPRSVTIPGDSPRSMLVAQVRAIDPDS 235

Query: 396 DNR--LHYEIT---GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS 450
                + Y ++       +  FS+ S  G   I +AQ L        +L V A+      
Sbjct: 236 ATNAAIIYSLSPKVSERAKKLFSLDSLTGD--IRLAQDLHSDTSEELLLKVLASSQHCPP 293

Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510
              +V ++I         +       +   +   G  VL  +   + + I  ++    +S
Sbjct: 294 ADTLVTVSILPK-----AYRELMIKIAFIGEHQKGAMVLPENQPPTALAI-LELEGD-NS 346

Query: 511 EISNEAVAHHDQQFVINPQTGA--ITTNKLLDRETMSGYLLTVTARD---GGVPSLSDTT 565
            IS+     +   F ++PQ G   ++T+K LD E  S Y + V AR     G  S     
Sbjct: 347 FISSSLTIENKVPFSLSPQNGKYLLSTSKPLDHEMKSDYSIGVVARGTSADGSASAPSRH 406

Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625
            + + V DVNDN P F +  Y   + E+   G ++  V A+DAD G NGR+ Y L   + 
Sbjct: 407 ILRVMVADVNDNAPNFLRSHYQLEVEENNRPGMTLLHVSASDADGGCNGRVTYRLG--NH 464

Query: 626 EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685
               F + P +G +  + +LDRE  A H ++  A D G+PP  S   V +++ D ND+ P
Sbjct: 465 TSTVFSVHPVTGRLSASTSLDREQQAAHLIRVFARDSGSPPLESAATVSVRVLDQNDNAP 524

Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745
           VF +    F++ E+ P+ T +G +   DPDEG N  +    K  ++   F + + QG   
Sbjct: 525 VFVTPHFIFFVPEDVPLFTEVGAVSVSDPDEGDNGNMELFFK--NNGGPFCVNSTQGI-- 580

Query: 746 AELVTMVDLDYESPRKKYELVIRAAS----PPLWNDVRVEILVTDVNDNAP 792
             L T  +LD+E   ++YEL + A+       L +  RV I V DVNDN P
Sbjct: 581 --LHTTTNLDHEI-EQRYELYLLASDRGYPSALTSTSRVTIFVVDVNDNPP 628



 Score =  130 bits (313), Expect = 7e-28
 Identities = 99/339 (29%), Positives = 155/339 (45%), Gaps = 32/339 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ V D ND++P F    Y+  V E    G T+L + A+D D G N  V Y +   T+  
Sbjct: 409 RVMVADVNDNAPNFLRSHYQLEVEENNRPGMTLLHVSASDADGGCNGRVTYRLGNHTST- 467

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                              VF +   +G L    SLDRE+ A + + V A D  SP    
Sbjct: 468 -------------------VFSVHPVTGRLSASTSLDREQQAAHLIRVFARDSGSP---P 505

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           L S AT+ V ++D NDN P F    +   V ED+ +     +  +  +D D G N  +  
Sbjct: 506 LESAATVSVRVLDQNDNAPVFVTPHFIFFVPEDVPLFTE--VGAVSVSDPDEGDNGNME- 562

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR-SNTTQLLINIR 248
            +   N    F ++S  G +     LD+E  + Y L + A D G PS  ++T+++ I + 
Sbjct: 563 -LFFKNNGGPFCVNSTQGILHTTTNLDHEIEQRYELYLLASDRGYPSALTSTSRVTIFVV 621

Query: 249 DVNDNAPRFYTSLFQES---VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
           DVNDN P+        S   V  +   G  + ++ A D D G+N+E+TYT+   +   + 
Sbjct: 622 DVNDNPPKVILPSSNSSCLTVPADTIAGTVVTKIHAIDEDSGLNSEVTYTVVAPEPARST 681

Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP 344
            +   +D RSG + T+ QL ++    + L V   D G P
Sbjct: 682 AV-FKVDSRSGNITTAEQLLQKDLGMHHLFVVVRDQGKP 719



 Score =  122 bits (293), Expect = 2e-25
 Identities = 134/520 (25%), Positives = 217/520 (41%), Gaps = 27/520 (5%)

Query: 366 FMPGQYEVELAEDEPPGTPV---VTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422
           F   +  + ++ED   GT +   V     DA  ++ +HY +   N  G F +T +    +
Sbjct: 97  FEKSEIHLWVSEDATVGTSLLLDVQAVDRDAGRNSEVHYRLEDPN--GVFGLTFKEDGPI 154

Query: 423 ITVAQPLDFKQERR--YVLTVSATDSGGR--SDTAMVQINITDANNYAPVFE-NAPYTAS 477
           I++       +E R  Y + + A D G    S TA + + +TD ++  P F  + P + +
Sbjct: 155 ISLVVQTALDRETRDFYEVKLEAADCGSNPLSATATLIVTVTDVDDNCPSFSPDNPRSVT 214

Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
           +  D+P    V  V A D D   NA I YSLS ++S  A     + F ++  TG I   +
Sbjct: 215 IPGDSPRSMLVAQVRAIDPDSATNAAIIYSLSPKVSERA----KKLFSLDSLTGDIRLAQ 270

Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
            L  +T    LL V A     P  +DT  V +S++     E + K   +     + A+V 
Sbjct: 271 DLHSDTSEELLLKVLASSQHCPP-ADTL-VTVSILPKAYRELMIKIA-FIGEHQKGAMV- 326

Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEG-SFVIDPASG--VIRTNKALDRESVATHD 654
              +Q     A + L G   +       E    F + P +G  ++ T+K LD E  + + 
Sbjct: 327 LPENQPPTALAILELEGDNSFISSSLTIENKVPFSLSPQNGKYLLSTSKPLDHEMKSDYS 386

Query: 655 LKAVAID---GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711
           +  VA      G+    S  I+ + + D+ND+ P F        + EN+  G T+  + A
Sbjct: 387 IGVVARGTSADGSASAPSRHILRVMVADVNDNAPNFLRSHYQLEVEENNRPGMTLLHVSA 446

Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771
            D D G N  V Y + G   S  FS+    G   A   T +D + ++          + S
Sbjct: 447 SDADGGCNGRVTYRL-GNHTSTVFSVHPVTGRLSAS--TSLDREQQAAHLIRVFARDSGS 503

Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRI 831
           PPL +   V + V D NDNAPV      IF   +D       G V   D D  D     +
Sbjct: 504 PPLESAATVSVRVLDQNDNAPVFVTPHFIFFVPEDVPLFTEVGAVSVSDPDEGDNGNMEL 563

Query: 832 LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
              NN     +N T G +  +  L+  + +   + +  +D
Sbjct: 564 FFKNNGGPFCVNSTQGILHTTTNLDHEIEQRYELYLLASD 603



 Score = 72.1 bits (169), Expect = 2e-10
 Identities = 64/237 (27%), Positives = 104/237 (43%), Gaps = 31/237 (13%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + VLD ND++PVF    +   V E     T V  +  +D D G N  +E    L   +  
Sbjct: 514 VRVLDQNDNAPVFVTPHFIFFVPEDVPLFTEVGAVSVSDPDEGDNGNME----LFFKNNG 569

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            P                 F ++   G L T  +LD E   RY + + A+D+  P    L
Sbjct: 570 GP-----------------FCVNSTQGILHTTTNLDHEIEQRYELYLLASDRGYP--SAL 610

Query: 131 SSTATIHVNIIDDNDNYPQF---SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
           +ST+ + + ++D NDN P+    S  +  ++V  D       V+ KI A D D G NS +
Sbjct: 611 TSTSRVTIFVVDVNDNPPKVILPSSNSSCLTVPAD--TIAGTVVTKIHAIDEDSGLNSEV 668

Query: 188 RYAIIG---GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
            Y ++      +   F +DS SG+++  + L  + +  + L +  +D G P    TT
Sbjct: 669 TYTVVAPEPARSTAVFKVDSRSGNITTAEQLLQKDLGMHHLFVVVRDQGKPIPLYTT 725


>UniRef50_Q60H51 Cluster: Protocadherin2-gamma-v5-sCP1; n=11;
           Clupeocephala|Rep: Protocadherin2-gamma-v5-sCP1 - Danio
           rerio (Zebrafish) (Brachydanio rerio)
          Length = 969

 Score =  233 bits (570), Expect = 5e-59
 Identities = 157/570 (27%), Positives = 273/570 (47%), Gaps = 27/570 (4%)

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
           ++ + ++D+NDNAP F        +SEN  +G      +A D D G+N   +Y +   D 
Sbjct: 129 RVTVEVQDINDNAPLFPKESVNLEISENAVLGARFPLDRAMDTDVGLNGIQSYKLHPTDN 188

Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
                  +T   +   +    +LDRE + + +L++ ATDGG P +S T            
Sbjct: 189 FKLEVHSLTDGNKYIEMILQRELDREERDEIKLVLLATDGGSPQKSGTVKIHVTILDAND 248

Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH----YEITGGNTRGRFSITSQ 417
                    ++ E+ E+ P GT + T++A DADE    H    + +     R  F+I S+
Sbjct: 249 NAPVCKQSVFKTEVRENSPAGTVMGTVSAADADEGVNGHVSYYFALANKEERELFNINSE 308

Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTAS 477
            G   +T+   LD++ +  Y L ++A D GG SDT  + I++TD N+  P  +   ++ +
Sbjct: 309 TGE--VTLLAHLDYESQNSYQLNINARDKGGLSDTCKIVIDVTDENDNPPTIQLMSFSNT 366

Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
           + E++P+GTTV V++  D+D G N  + +S++  I  +  +   + +       ++ T+ 
Sbjct: 367 IAENSPVGTTVAVINVEDADSGKNGLVHFSINQNIPFKIESTFSEYY-------SLITDD 419

Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
           +LDRET++ Y +T+   D G P+      + + + DVNDN P F    Y   + E+   G
Sbjct: 420 MLDRETVTEYNITILVSDQGSPARHSNKTLNVKISDVNDNPPKFGSDEYKTFVNENNSPG 479

Query: 598 TSVSQVGATDADVGLNGRIHYELDPKD---REEGSFV-IDPASGVIRTNKALDRESVATH 653
            ++  V A DAD G N ++ Y L  +D       S V +D  +G +   K+ D E + + 
Sbjct: 480 VTILTVKANDADWGPNAQLSYFLKDEDIRGAPLSSLVSVDALTGTVHAVKSFDFEQLKSF 539

Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP--VFESDCLTFYISENSP----IGTTIG 707
                A DGG+PP SS V + I I+D ND+ P  ++        ++E  P    +G  + 
Sbjct: 540 SFNVTARDGGSPPLSSEVTITINIQDQNDNAPQVLYPVQTGASVVAEIVPRAVDVGYLVT 599

Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
           ++ A D D G NA + Y ++   D   F +  + G  +   V  V  D ++ ++K  +V+
Sbjct: 600 KVVAVDVDSGQNAWLSYKLQKAPDRALFEVGLQNG--EIRTVRQV-TDKDAVKQKLTVVV 656

Query: 768 RAASPPLWNDVRVEILVTDVNDNAPVMKDF 797
                P  + V V I V   +    V+ +F
Sbjct: 657 EDNGQPSRSAV-VSINVAVADSFPEVLSEF 685



 Score =  215 bits (526), Expect = 1e-53
 Identities = 174/600 (29%), Positives = 271/600 (45%), Gaps = 33/600 (5%)

Query: 97  GALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT 156
           G L+ +  +DRE++ + T     +     + +       + V + D NDN P F +++  
Sbjct: 93  GTLVVKERIDREELCKQTT--PCSFSFDLIVENPIQLHRVTVEVQDINDNAPLFPKESVN 150

Query: 157 VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG-----DVSL 211
           + + E+  +     + +  A D DVG N    Y +       +  + SL+      ++ L
Sbjct: 151 LEISENAVLGARFPLDR--AMDTDVGLNGIQSYKL-HPTDNFKLEVHSLTDGNKYIEMIL 207

Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271
            + LD E+    +LV+ A DGGSP +S T ++ + I D NDNAP    S+F+  V EN P
Sbjct: 208 QRELDREERDEIKLVLLATDGGSPQKSGTVKIHVTILDANDNAPVCKQSVFKTEVRENSP 267

Query: 272 IGYSIVRVQAYDADEGVNAELTY--TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329
            G  +  V A DADEGVN  ++Y   + +K+     +L   I+  +G V     LD E+Q
Sbjct: 268 AGTVMGTVSAADADEGVNGHVSYYFALANKE---EREL-FNINSETGEVTLLAHLDYESQ 323

Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389
             YQL + A D G    S T                     +   +AE+ P GT V  + 
Sbjct: 324 NSYQLNINARDKGG--LSDTCKIVIDVTDENDNPPTIQLMSFSNTIAENSPVGTTVAVIN 381

Query: 390 ATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447
             DAD  ++  +H+ I   N   +   T      LIT    LD +    Y +T+  +D G
Sbjct: 382 VEDADSGKNGLVHFSI-NQNIPFKIESTFSEYYSLIT-DDMLDRETVTEYNITILVSDQG 439

Query: 448 --GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505
              R     + + I+D N+  P F +  Y   V E+   G T+L V A D+D G NAQ++
Sbjct: 440 SPARHSNKTLNVKISDVNDNPPKFGSDEYKTFVNENNSPGVTILTVKANDADWGPNAQLS 499

Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTT 565
           Y L  E    A         ++  TG +   K  D E +  +   VTARDGG P LS   
Sbjct: 500 YFLKDEDIRGAPL--SSLVSVDALTGTVHAVKSFDFEQLKSFSFNVTARDGGSPPLSSEV 557

Query: 566 DVEISVVDVNDNEPVFKQQLYT-----ANIMEDAL-VGTSVSQVGATDADVGLNGRIHYE 619
            + I++ D NDN P     + T     A I+  A+ VG  V++V A D D G N  + Y+
Sbjct: 558 TITINIQDQNDNAPQVLYPVQTGASVVAEIVPRAVDVGYLVTKVVAVDVDSGQNAWLSYK 617

Query: 620 LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679
           L  K  +   F +   +G IRT + +  +      L  V  D G P +S+ V +++ + D
Sbjct: 618 LQ-KAPDRALFEVGLQNGEIRTVRQVTDKDAVKQKLTVVVEDNGQPSRSAVVSINVAVAD 676



 Score =  185 bits (450), Expect = 2e-44
 Identities = 142/470 (30%), Positives = 221/470 (47%), Gaps = 41/470 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + +LD ND++PV +   ++  VRE + +GT + T+ A D D G N  V Y   L      
Sbjct: 241 VTILDANDNAPVCKQSVFKTEVRENSPAGTVMGTVSAADADEGVNGHVSYYFALA----- 295

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           N E+            +++F I+  +G +   A LD E    Y + + A D+       L
Sbjct: 296 NKEE------------RELFNINSETGEVTLLAHLDYESQNSYQLNINARDKGG-----L 338

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           S T  I +++ D+NDN P     +++ ++ E+  V     +A I   DAD G N  + ++
Sbjct: 339 SDTCKIVIDVTDENDNPPTIQLMSFSNTIAENSPV--GTTVAVINVEDADSGKNGLVHFS 396

Query: 191 IIGGNTQMQFSIDSLSGDV-SLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
           I   N  + F I+S   +  SL+    LD E V  Y + I   D GSP+R +   L + I
Sbjct: 397 I---NQNIPFKIESTFSEYYSLITDDMLDRETVTEYNITILVSDQGSPARHSNKTLNVKI 453

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NVD 306
            DVNDN P+F +  ++  V+EN   G +I+ V+A DAD G NA+L+Y + D+D  G  + 
Sbjct: 454 SDVNDNPPKFGSDEYKTFVNENNSPGVTILTVKANDADWGPNAQLSYFLKDEDIRGAPLS 513

Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
             +++D  +G V+     D E    +   VTA DGG PP S+  T               
Sbjct: 514 SLVSVDALTGTVHAVKSFDFEQLKSFSFNVTARDGGSPPLSSEVTITINIQDQNDNAPQV 573

Query: 367 M-PGQYEVELAEDEPP-----GTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQN 418
           + P Q    +  +  P     G  V  + A D D      L Y++     R  F +  QN
Sbjct: 574 LYPVQTGASVVAEIVPRAVDVGYLVTKVVAVDVDSGQNAWLSYKLQKAPDRALFEVGLQN 633

Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468
           G  + TV Q  D K   +  LTV   D+G  S +A+V IN+  A+++  V
Sbjct: 634 GE-IRTVRQVTD-KDAVKQKLTVVVEDNGQPSRSAVVSINVAVADSFPEV 681


>UniRef50_Q9Y5H6 Cluster: Protocadherin alpha 8 precursor; n=204;
           Mammalia|Rep: Protocadherin alpha 8 precursor - Homo
           sapiens (Human)
          Length = 950

 Score =  231 bits (566), Expect = 2e-58
 Identities = 172/614 (28%), Positives = 277/614 (45%), Gaps = 25/614 (4%)

Query: 87  QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146
           +D+  +  ++G L   + +DRE++   +   + +     + DR      + V + D NDN
Sbjct: 72  RDLLEVSLQNGILFVNSRIDREELCGRSA--ECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129

Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206
            P F  K   + V E   + D+    +  A+DADVGANS + Y +   +      ++S +
Sbjct: 130 PPVFRVKDQKLFVSES-RMPDSRFPLE-GASDADVGANSVLTYRL-SSHDYFMLDVNSKN 186

Query: 207 GDVSLV-----KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261
            +  LV     K+LD E   ++ L + A DGG P  + T QLL+ + DVNDNAP F  S 
Sbjct: 187 DENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSE 246

Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321
           ++  + EN   G +++++ A D DEG N  ++Y+      T  +D   +ID  +G +   
Sbjct: 247 YEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVID-HFSIDRNTGEIVIR 305

Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381
           G LD E +  Y++L+ ATD G PP +   T                     + + ED   
Sbjct: 306 GNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQF 365

Query: 382 GTPVVTLTATDADEDNRLHYEIT-GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440
           GT +  ++  D D         +   +   +   T +N   L+ +   LD ++   Y L 
Sbjct: 366 GTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLV-LDSALDRERVSAYELV 424

Query: 441 VSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498
           V+A D G  S   TA + + + D N+ AP F    YT  V E+ P G  +  VSA D+D 
Sbjct: 425 VTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADA 484

Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558
             NA ++YSL      E          ++ ++G +   + LD E +      V+ARD GV
Sbjct: 485 QENALVSYSLVERRVGERSL--SSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGV 542

Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQQLY-----TANIMEDALVGTS--VSQVGATDADVG 611
           P L     +++ V+D NDN P   +         A+ +    VG    V++V A DAD G
Sbjct: 543 PPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSG 602

Query: 612 LNGRIHYELDP-KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST 670
            N  + YEL P        F +   +G I T + LD      H L  +  D G P  ++T
Sbjct: 603 YNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTAT 662

Query: 671 VIVHIKIEDINDSP 684
             V + + +   +P
Sbjct: 663 ATVLVSLVESGQAP 676



 Score =  211 bits (515), Expect = 2e-52
 Identities = 163/549 (29%), Positives = 242/549 (44%), Gaps = 32/549 (5%)

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           + ++DVNDN P F     +  VSE+           A DAD G N+ LTY ++  DY   
Sbjct: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYF-M 179

Query: 305 VDLPITIDPRS-GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
           +D+    D      +     LDRE    + L +TATDGG P  + T              
Sbjct: 180 LDVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNA 239

Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITG---GNTRGRFSITSQN 418
             F   +YEV + E+   GT V+ L A+D DE  +  + Y             FSI    
Sbjct: 240 PTFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNT 299

Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTA 476
           G   I +   LDF+QE  Y + + ATD G    +    V + I D N+  P       + 
Sbjct: 300 GE--IVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSL 357

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
            V EDA  GT + ++S  D D G N Q+T SL   +  + V+     +       ++  +
Sbjct: 358 PVREDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYY-------SLVLD 410

Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
             LDRE +S Y L VTARDGG PSL  T  + + V DVNDN P F Q  YT  + E+   
Sbjct: 411 SALDRERVSAYELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPP 470

Query: 597 GTSVSQVGATDADVGLNGRIHYELDPK---DREEGSFV-IDPASGVIRTNKALDRESVAT 652
           G  +  V A DAD   N  + Y L  +   +R   S++ +   SG +   + LD E +  
Sbjct: 471 GCHIFTVSARDADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELEL 530

Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF-------ESDCLTFYISENSPIGTT 705
              +  A D G PP  S V + + + D ND+ P              +  +  +   G  
Sbjct: 531 LQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHV 590

Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD-YESPRKKYE 764
           + ++RA D D G NA + Y ++    ++S  +  R G    E+ T   LD  +SPR +  
Sbjct: 591 VAKVRAVDADSGYNAWLSYELQPA--ASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLL 648

Query: 765 LVIRAASPP 773
           ++++    P
Sbjct: 649 VLVKDHGEP 657



 Score =  184 bits (449), Expect = 2e-44
 Identities = 118/378 (31%), Positives = 192/378 (50%), Gaps = 12/378 (3%)

Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFE 480
           + + + LD +    + L ++ATD G    T  VQ+ +T  D N+ AP FE + Y   +FE
Sbjct: 194 LVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFE 253

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           +A  GTTV+ ++A+D D G N  I+YS +S +    + H    F I+  TG I     LD
Sbjct: 254 NADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDH----FSIDRNTGEIVIRGNLD 309

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
            E  + Y + + A D G P ++    V + ++D NDN P       +  + EDA  GT +
Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369

Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
           + +   D D G NG++   L P    +          ++  + ALDRE V+ ++L   A 
Sbjct: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLV-LDSALDRERVSAYELVVTAR 428

Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
           DGG+P   +T  + +++ D+ND+ P F     T ++ EN+P G  I  + A D D   NA
Sbjct: 429 DGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488

Query: 721 VVHYSI---KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS-PPLWN 776
           +V YS+   + G+ S S  +     S K   +  +D + E    ++++  R A  PPL +
Sbjct: 489 LVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHE-ELELLQFQVSARDAGVPPLGS 547

Query: 777 DVRVEILVTDVNDNAPVM 794
           +V +++ V D NDNAP +
Sbjct: 548 NVTLQVFVLDENDNAPAL 565



 Score =  177 bits (430), Expect = 5e-42
 Identities = 140/463 (30%), Positives = 208/463 (44%), Gaps = 37/463 (7%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + VLD ND++P FE  +YE  + E A +GTTV+ L A+D D G N  + Y+   +  +T+
Sbjct: 230 VTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLV-ETM 288

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                          V D F ID  +G ++ R +LD E+   Y +L+ ATD+  P    +
Sbjct: 289 ---------------VIDHFSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHP---PM 330

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           +   T+ V I+D NDN P+ +  + ++ V ED       VIA I   D D GAN  +  +
Sbjct: 331 AGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQF--GTVIALISVNDLDSGANGQVTCS 388

Query: 191 IIGGNTQMQFS-IDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
           ++     + F  + +     SLV    LD E+V +Y LV+ A+DGGSPS   T  L + +
Sbjct: 389 LM---PHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARDGGSPSLWATASLSVEV 445

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY-TGNVD 306
            DVNDNAP F    +   V EN P G  I  V A DAD   NA ++Y++ ++     ++ 
Sbjct: 446 ADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERSLS 505

Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
             I++   SG VY    LD E     Q  V+A D G PP  +  T               
Sbjct: 506 SYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPAL 565

Query: 367 MP-------GQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQ 417
           +        G     +      G  V  + A DAD      L YE+    +  R      
Sbjct: 566 LEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPAASSPRIPFRVG 625

Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT 460
              G I+  + LD     R+ L V   D G  + TA   + ++
Sbjct: 626 LYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668



 Score =  151 bits (366), Expect = 3e-34
 Identities = 132/450 (29%), Positives = 202/450 (44%), Gaps = 25/450 (5%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE--I 512
           V + + D N+  PVF        V E     +   +  A+D+DVG N+ +TY LSS    
Sbjct: 119 VDVEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYF 178

Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572
             +  + +D+  ++      +   K LDRE    + L +TA DGG P L+ T  + ++V+
Sbjct: 179 MLDVNSKNDENKLVE-----LVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVL 233

Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP--KDREEGSF 630
           DVNDN P F+Q  Y   I E+A  GT+V ++ A+D D G NG I Y  +   +      F
Sbjct: 234 DVNDNAPTFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHF 293

Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690
            ID  +G I     LD E    + +   A D G PP +    V ++I D ND+ P     
Sbjct: 294 SIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALT 353

Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750
            L+  + E++  GT I  I  +D D G N  V  S+        F L      +   LV 
Sbjct: 354 SLSLPVREDAQFGTVIALISVNDLDSGANGQVTCSLM---PHVPFKL-VSTFKNYYSLVL 409

Query: 751 MVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC 807
              LD E     YELV+ A    SP LW    + + V DVNDNAP     +      ++ 
Sbjct: 410 DSALDRERV-SAYELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENN 468

Query: 808 FPVGPFGRVPAYDADVTDK-------LQYRILSGNNANLILLNETTGSMTLSPQLNTNVP 860
            P      V A DAD  +        ++ R+   + ++ I ++  +G +     L+    
Sbjct: 469 PPGCHIFTVSARDADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEEL 528

Query: 861 KLATMEVSVTD-GVNEIKAMMQLSVRLITE 889
           +L   +VS  D GV  + + + L V ++ E
Sbjct: 529 ELLQFQVSARDAGVPPLGSNVTLQVFVLDE 558



 Score =  122 bits (294), Expect = 1e-25
 Identities = 97/326 (29%), Positives = 148/326 (45%), Gaps = 21/326 (6%)

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
           SV E+A  GT V  ++    D+G+       L   +   A   H     ++ Q G +  N
Sbjct: 34  SVPEEAKHGTFVGRIA---QDLGLELA---ELVPRLFRVASKRHRDLLEVSLQNGILFVN 87

Query: 537 KLLDRETMSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
             +DRE + G     +   +  V        V++ V DVNDN PVF+ +     + E  +
Sbjct: 88  SRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDNPPVFRVKDQKLFVSESRM 147

Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKD---REEGSFVIDPASGVIRTNKALDRESVAT 652
             +     GA+DADVG N  + Y L   D    +  S   +     +   K+LDRE    
Sbjct: 148 PDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDENKLVELVLRKSLDREDAPA 207

Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
           H L   A DGG P  + TV + + + D+ND+ P FE       I EN+  GTT+ ++ A 
Sbjct: 208 HHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIKLNAS 267

Query: 713 DPDEGPNAVVHYSIKGGDDS---NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
           DPDEG N  + YS     ++   + FS++   G    E+V   +LD+E     Y+++I A
Sbjct: 268 DPDEGANGAISYSFNSLVETMVIDHFSIDRNTG----EIVIRGNLDFEQ-ENLYKILIDA 322

Query: 770 AS---PPLWNDVRVEILVTDVNDNAP 792
                PP+     V + + D NDN P
Sbjct: 323 TDKGHPPMAGHCTVLVRILDKNDNVP 348


>UniRef50_UPI0000E80F11 Cluster: PREDICTED: similar to protocadherin
            LKC; n=2; Gallus gallus|Rep: PREDICTED: similar to
            protocadherin LKC - Gallus gallus
          Length = 1497

 Score =  231 bits (565), Expect = 2e-58
 Identities = 234/819 (28%), Positives = 375/819 (45%), Gaps = 91/819 (11%)

Query: 36   ASSGTTVLTLKATDQDIGKNAEV-EYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDG 94
            A+SG T      T   + ++ ++ E+  +L+  D     D               F  + 
Sbjct: 218  AASGNTAPIFNMTIVYVAEDLQIGEFAFQLMAYDI----DGDTITYSISGSDSFYFTANA 273

Query: 95   RSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKT 154
            ++G +  R  LDRE  AR T+LV  +D    +++ +S    I V   D NDN P F    
Sbjct: 274  QTGVVTLRNLLDRESQARLTILVTVSDG---INEAVSRRLPIIVE--DRNDNAPVFQNLP 328

Query: 155  YTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI---IGGNTQMQ--FSIDSLSGDV 209
            Y  SV E+ +V    VI  + A D+D G  + + Y+I   I   T+    F I S SG V
Sbjct: 329  YETSVLENTTV--GSVIYTVFANDSDTGTAARVSYSIQEVIPDTTKNHRLFYILS-SGSV 385

Query: 210  SLVKTLDYEQVRSYRLVIRAQDGGSPSR------SNTTQLLINIRDVNDNAPRFYTSLFQ 263
             L  +LDY     ++L I AQDGG   R      S+TT L I + DV +  PRF    + 
Sbjct: 386  VLNNSLDYTMNTFFQLKILAQDGGGLLRNETVIQSSTTYLSITVIDVPNLDPRFLNEPYS 445

Query: 264  ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323
             SV E  P+G +++ V A D D GVN +++Y+ T      N  +P  I+  +G +  S  
Sbjct: 446  GSVPEGCPVGTTVLTVTAMDRDTGVNDKISYSFT------NASVPFAINDTTGTITVSQV 499

Query: 324  LDRETQAKYQLL--VTATDG-----GDPPRSATATXXXXXXXXXXXXXXFM--------- 367
            LDRE     ++L  V A +      G+  +++T                +          
Sbjct: 500  LDREQLPSEEVLLEVLARESNLDIYGNVAQASTLVTVLVTDVNDNKPQFYQCSSNCNFIH 559

Query: 368  -PGQYEVELAEDEPPGTPV--VTLTATDADEDNRLHYEI-TGGNTRGRFSITSQ----NG 419
                +   + E      PV  +++ A D D+     +E+   G +   F+++       G
Sbjct: 560  TQSNFTGSIIEHSSSKVPVSNLSIVARDPDKGTNGTFELYLQGTSASAFTVSPTRIVGTG 619

Query: 420  RGLITVAQP--LDFKQERRYVLTVSATDSGGRSD---TAMVQINITDANNYAPVFENAPY 474
               I V  P  +D++     V+ + A D+G  +D   TA V I++ D N++ P F  + Y
Sbjct: 620  EVQILVQNPSAVDYEITHVMVVQLIANDTGNPTDCCSTATVTIDLIDTNDHIPEFPQSTY 679

Query: 475  TASVFEDAPIGTTVLV-VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA- 532
               V E++P GT +   ++A D D G + QITY L  E   E        F++N  +GA 
Sbjct: 680  NLRVMENSPDGTIIATNITAYDPDSGASGQITYQLLPESIQEI-------FMVNATSGAV 732

Query: 533  -ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
             +    LLDRE    Y   + A+DGG  ++  TT +EI+V+D NDNEP+     Y  ++ 
Sbjct: 733  LVRNGSLLDREMRPVYYANLQAKDGG--NMMGTTLLEITVLDKNDNEPIIIGS-YFISVE 789

Query: 592  EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV- 650
            E   V T +  +   D +   N  + +++ P      +F I   +G +   + LDRE+V 
Sbjct: 790  EGQNVSTQIRAID-NDEEGTPNSELGFKIVP-GLYSNNFTISQTTGELHNIEPLDREAVD 847

Query: 651  --ATHDLKAVAI-DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
              A   +  V + D G P  S+ V V I + D+ND+ PVF      F I E+S  G+ +G
Sbjct: 848  DEAGQMVVTVEVYDHGVPQLSTMVNVTITVADVNDNTPVFLQQSYEFSIFESSD-GSFVG 906

Query: 708  EIRAHDPDEGP-NAVVHYSIKGGDDSNSFSL-ETRQG----SDKAELVTMVDLDYESPRK 761
            ++ A D D    N+ + + ++    S++F +  +R G    S +  L   V ++YE+ ++
Sbjct: 907  DVMATDADRTEINSRISFQLEKSTGSSNFLISSSRLGPGNYSGRLSLNPGVSVNYEAMQE 966

Query: 762  K-YELVIRA---ASPPLWNDVRVEILVT--DVNDNAPVM 794
            K + LV+ A   A+    N   V +LV   DVND  P +
Sbjct: 967  KLFSLVVLAENTAADNSGNIANVSVLVNILDVNDEPPTI 1005



 Score =  197 bits (481), Expect = 3e-48
 Identities = 228/874 (26%), Positives = 370/874 (42%), Gaps = 95/874 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V D ND++PVF+   YE SV E  + G+ + T+ A D D G  A V Y+I+ V  DT 
Sbjct: 312  IIVEDRNDNAPVFQNLPYETSVLENTTVGSVIYTVFANDSDTGTAARVSYSIQEVIPDTT 371

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                              +F I   SG+++   SLD      + + + A D    + +  
Sbjct: 372  KNHR--------------LFYILS-SGSVVLNNSLDYTMNTFFQLKILAQDGGGLLRNET 416

Query: 131  ---SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
               SST  + + +ID  +  P+F  + Y+ SV E   V     +  + A D D G N  I
Sbjct: 417  VIQSSTTYLSITVIDVPNLDPRFLNEPYSGSVPEGCPV--GTTVLTVTAMDRDTGVNDKI 474

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIR--AQDGGSPSRSNTTQ--- 242
             Y+    N  + F+I+  +G +++ + LD EQ+ S  +++   A++       N  Q   
Sbjct: 475  SYSFT--NASVPFAINDTTGTITVSQVLDREQLPSEEVLLEVLARESNLDIYGNVAQAST 532

Query: 243  -LLINIRDVNDNAPRFY---------------TSLFQESVSENVPIGYSIVRVQAYDADE 286
             + + + DVNDN P+FY               T    E  S  VP+  S + + A D D+
Sbjct: 533  LVTVLVTDVNDNKPQFYQCSSNCNFIHTQSNFTGSIIEHSSSKVPV--SNLSIVARDPDK 590

Query: 287  GVNA--ELTYTMTDKD-YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD 343
            G N   EL    T    +T +    +        V     +D E      + + A D G+
Sbjct: 591  GTNGTFELYLQGTSASAFTVSPTRIVGTGEVQILVQNPSAVDYEITHVMVVQLIANDTGN 650

Query: 344  PPR-SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT-LTATDADE--DNRL 399
            P    +TAT              F    Y + + E+ P GT + T +TA D D     ++
Sbjct: 651  PTDCCSTATVTIDLIDTNDHIPEFPQSTYNLRVMENSPDGTIIATNITAYDPDSGASGQI 710

Query: 400  HYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINI 459
             Y++   + +  F + + +G  L+     LD +    Y   + A D G    T +++I +
Sbjct: 711  TYQLLPESIQEIFMVNATSGAVLVRNGSLLDREMRPVYYANLQAKDGGNMMGTTLLEITV 770

Query: 460  TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAH 519
             D N+  P+   + Y  SV E   + T +  +   D +   N+++ + +   +       
Sbjct: 771  LDKNDNEPIIIGS-YFISVEEGQNVSTQIRAID-NDEEGTPNSELGFKIVPGL------- 821

Query: 520  HDQQFVINPQTGAITTNKLLDRETMSG----YLLTVTARDGGVPSLSDTTDVEISVVDVN 575
            +   F I+  TG +   + LDRE +       ++TV   D GVP LS   +V I+V DVN
Sbjct: 822  YSNNFTISQTTGELHNIEPLDREAVDDEAGQMVVTVEVYDHGVPQLSTMVNVTITVADVN 881

Query: 576  DNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDP 634
            DN PVF QQ Y  +I E +  G+ V  V ATDAD   +N RI ++L+ K     +F+I  
Sbjct: 882  DNTPVFLQQSYEFSIFESS-DGSFVGDVMATDADRTEINSRISFQLE-KSTGSSNFLISS 939

Query: 635  A-------SGVIRTNK--ALDRESVATHDLKAVAIDGGTPPQSS----TVIVHIKIEDIN 681
            +       SG +  N   +++ E++       V +   T   +S     V V + I D+N
Sbjct: 940  SRLGPGNYSGRLSLNPGVSVNYEAMQEKLFSLVVLAENTAADNSGNIANVSVLVNILDVN 999

Query: 682  DSPP-VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV-HYSI---KGGDDSNSFS 736
            D PP +  S      + EN      +  + A D D   + V    S+   KGG  +    
Sbjct: 1000 DEPPTIVPSSLEGVSVRENGTQQDLVHTVFASDRDTNHSLVFEELSVACYKGGSSAGEVC 1059

Query: 737  LE-TRQGSDKAELVTMVDLDYE------SPRKKYELVIRAASPPLWNDVRVEILVTDVND 789
             +      + + L    D+DYE         +  +L  +  +    N+  ++I + D+ND
Sbjct: 1060 WDWFVLLPNGSVLANSFDIDYELCDVVQLTMRVEDLYTQKGNQYSQNET-LQIRIIDIND 1118

Query: 790  NAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD 822
            NAPV       F    +  PV      V A DAD
Sbjct: 1119 NAPVFLPVSGTFVVVPEISPVDLQVATVKATDAD 1152



 Score =  177 bits (430), Expect = 5e-42
 Identities = 191/671 (28%), Positives = 295/671 (43%), Gaps = 81/671 (12%)

Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325
           V+E++ IG    ++ AYD D      +TY+++  D         T + ++G V     LD
Sbjct: 234 VAEDLQIGEFAFQLMAYDIDGDT---ITYSISGSD-----SFYFTANAQTGVVTLRNLLD 285

Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
           RE+QA+  +LVT +DG +   S                   +P  YE  + E+   G+ +
Sbjct: 286 RESQARLTILVTVSDGINEAVSRRLPIIVEDRNDNAPVFQNLP--YETSVLENTTVGSVI 343

Query: 386 VTLTATDADEDN--RLHY---EITGGNTRGR--FSITSQNGRGLITVAQPLDFKQERRYV 438
            T+ A D+D     R+ Y   E+    T+    F I S    G + +   LD+     + 
Sbjct: 344 YTVFANDSDTGTAARVSYSIQEVIPDTTKNHRLFYILSS---GSVVLNNSLDYTMNTFFQ 400

Query: 439 LTVSATDSGG--------RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
           L + A D GG        +S T  + I + D  N  P F N PY+ SV E  P+GTTVL 
Sbjct: 401 LKILAQDGGGLLRNETVIQSSTTYLSITVIDVPNLDPRFLNEPYSGSVPEGCPVGTTVLT 460

Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG--YL 548
           V+A D D G+N +I+YS     +N +V      F IN  TG IT +++LDRE +     L
Sbjct: 461 VTAMDRDTGVNDKISYS----FTNASV-----PFAINDTTGTITVSQVLDREQLPSEEVL 511

Query: 549 LTVTARDGGVPSLSD----TTDVEISVVDVNDNEPVF-----------KQQLYTANIMED 593
           L V AR+  +    +    +T V + V DVNDN+P F            Q  +T +I+E 
Sbjct: 512 LEVLARESNLDIYGNVAQASTLVTVLVTDVNDNKPQFYQCSSNCNFIHTQSNFTGSIIEH 571

Query: 594 ALVGTSVSQVG--ATDADVGLNGRIHYELDPKDREEGSFVIDP----ASG----VIRTNK 643
           +     VS +   A D D G NG   +EL  +     +F + P     +G    +++   
Sbjct: 572 SSSKVPVSNLSIVARDPDKGTNGT--FELYLQGTSASAFTVSPTRIVGTGEVQILVQNPS 629

Query: 644 ALDRESVATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
           A+D E      ++ +A D G P    ST  V I + D ND  P F        + ENSP 
Sbjct: 630 AVDYEITHVMVVQLIANDTGNPTDCCSTATVTIDLIDTNDHIPEFPQSTYNLRVMENSPD 689

Query: 703 GTTIG-EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761
           GT I   I A+DPD G +  + Y +        F +    G   A LV    L     R 
Sbjct: 690 GTIIATNITAYDPDSGASGQITYQLLPESIQEIFMVNATSG---AVLVRNGSLLDREMRP 746

Query: 762 KYELVIRAA-SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD 820
            Y   ++A     +     +EI V D NDN P++      F + ++   V    R    D
Sbjct: 747 VYYANLQAKDGGNMMGTTLLEITVLDKNDNEPII--IGSYFISVEEGQNVSTQIRAIDND 804

Query: 821 ADVT--DKLQYRILSGNNANLILLNETTGSM-TLSPQLNTNVPKLA---TMEVSVTD-GV 873
            + T   +L ++I+ G  +N   +++TTG +  + P     V   A    + V V D GV
Sbjct: 805 EEGTPNSELGFKIVPGLYSNNFTISQTTGELHNIEPLDREAVDDEAGQMVVTVEVYDHGV 864

Query: 874 NEIKAMMQLSV 884
            ++  M+ +++
Sbjct: 865 PQLSTMVNVTI 875



 Score =  158 bits (384), Expect = 2e-36
 Identities = 138/515 (26%), Positives = 244/515 (47%), Gaps = 52/515 (10%)

Query: 373 VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432
           V +AED   G     L A D D D  + Y I+G ++   F  T+    G++T+   LD +
Sbjct: 232 VYVAEDLQIGEFAFQLMAYDIDGDT-ITYSISGSDS---FYFTANAQTGVVTLRNLLDRE 287

Query: 433 QERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492
            + R  + V+ +D    + +  + I + D N+ APVF+N PY  SV E+  +G+ +  V 
Sbjct: 288 SQARLTILVTVSDGINEAVSRRLPIIVEDRNDNAPVFQNLPYETSVLENTTVGSVIYTVF 347

Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552
           A DSD G  A+++YS+  E+  +   +H   ++++  +G++  N  LD    + + L + 
Sbjct: 348 ANDSDTGTAARVSYSI-QEVIPDTTKNHRLFYILS--SGSVVLNNSLDYTMNTFFQLKIL 404

Query: 553 ARDGG------VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
           A+DGG          S TT + I+V+DV + +P F  + Y+ ++ E   VGT+V  V A 
Sbjct: 405 AQDGGGLLRNETVIQSSTTYLSITVIDVPNLDPRFLNEPYSGSVPEGCPVGTTVLTVTAM 464

Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD--LKAVAIDG-- 662
           D D G+N +I Y           F I+  +G I  ++ LDRE + + +  L+ +A +   
Sbjct: 465 DRDTGVNDKISYSF---TNASVPFAINDTTGTITVSQVLDREQLPSEEVLLEVLARESNL 521

Query: 663 ---GTPPQSSTVIVHIKIEDINDSPPVF---ESDCLTFYISEN----------SPIGTTI 706
              G   Q+ST +V + + D+ND+ P F    S+C   +   N          S +  + 
Sbjct: 522 DIYGNVAQAST-LVTVLVTDVNDNKPQFYQCSSNCNFIHTQSNFTGSIIEHSSSKVPVSN 580

Query: 707 GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD----LDYESPR-K 761
             I A DPD+G N      ++ G  +++F++   +     E+  +V     +DYE     
Sbjct: 581 LSIVARDPDKGTNGTFELYLQ-GTSASAFTVSPTRIVGTGEVQILVQNPSAVDYEITHVM 639

Query: 762 KYELVIRAASPP--LWNDVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVGPF--GRV 816
             +L+      P    +   V I + D ND+ P     Q  +N    +  P G      +
Sbjct: 640 VVQLIANDTGNPTDCCSTATVTIDLIDTNDHIPEFP--QSTYNLRVMENSPDGTIIATNI 697

Query: 817 PAYDAD--VTDKLQYRILSGNNANLILLNETTGSM 849
            AYD D   + ++ Y++L  +   + ++N T+G++
Sbjct: 698 TAYDPDSGASGQITYQLLPESIQEIFMVNATSGAV 732



 Score =  157 bits (381), Expect = 4e-36
 Identities = 194/770 (25%), Positives = 318/770 (41%), Gaps = 87/770 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I V+D  +  P F  + Y  SV EG   GTTVLT+ A D+D G N ++ Y+    +    
Sbjct: 427  ITVIDVPNLDPRFLNEPYSGSVPEGCPVGTTVLTVTAMDRDTGVNDKISYSFTNASVP-- 484

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS--PVSD 128
                               F I+  +G +     LDRE++    VL++   + S   +  
Sbjct: 485  -------------------FAINDTTGTITVSQVLDREQLPSEEVLLEVLARESNLDIYG 525

Query: 129  RLSSTAT-IHVNIIDDNDNYPQF-----------SEKTYTVSVDEDISVTDNPVIAKIKA 176
             ++  +T + V + D NDN PQF           ++  +T S+ E  S         I A
Sbjct: 526  NVAQASTLVTVLVTDVNDNKPQFYQCSSNCNFIHTQSNFTGSIIEHSSSKVPVSNLSIVA 585

Query: 177  TDADVGANSAIRYAIIGGNTQMQFSIDSL----SGDVSLV----KTLDYEQVRSYRLVIR 228
             D D G N       + G +   F++       +G+V ++      +DYE      + + 
Sbjct: 586  RDPDKGTNGTFEL-YLQGTSASAFTVSPTRIVGTGEVQILVQNPSAVDYEITHVMVVQLI 644

Query: 229  AQDGGSPSRS-NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV-RVQAYDADE 286
            A D G+P+   +T  + I++ D ND+ P F  S +   V EN P G  I   + AYD D 
Sbjct: 645  ANDTGNPTDCCSTATVTIDLIDTNDHIPEFPQSTYNLRVMENSPDGTIIATNITAYDPDS 704

Query: 287  GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT--SGQLDRETQAKYQLLVTATDGGDP 344
            G + ++TY +  +    ++     ++  SG V       LDRE +  Y   + A DGG+ 
Sbjct: 705  GASGQITYQLLPE----SIQEIFMVNATSGAVLVRNGSLLDREMRPVYYANLQAKDGGN- 759

Query: 345  PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN-RLHYEI 403
                  T               + G Y + + E +   T +  +   +    N  L ++I
Sbjct: 760  --MMGTTLLEITVLDKNDNEPIIIGSYFISVEEGQNVSTQIRAIDNDEEGTPNSELGFKI 817

Query: 404  TGGNTRGRFSITSQNGRGLITVAQPLDFK----QERRYVLTVSATDSGGRSDTAMVQINI 459
              G     F+I+   G   +   +PLD +    +  + V+TV   D G    + MV + I
Sbjct: 818  VPGLYSNNFTISQTTGE--LHNIEPLDREAVDDEAGQMVVTVEVYDHGVPQLSTMVNVTI 875

Query: 460  T--DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEA 516
            T  D N+  PVF    Y  S+FE +  G+ V  V ATD+D   IN++I++ L     +  
Sbjct: 876  TVADVNDNTPVFLQQSYEFSIFESSD-GSFVGDVMATDADRTEINSRISFQLEKSTGSSN 934

Query: 517  VAHHDQQFVINPQTGAITTNK--LLDRETMSGYL--LTVTARDGGVPSLSDTTDVEI--S 570
                  +      +G ++ N    ++ E M   L  L V A +    +  +  +V +  +
Sbjct: 935  FLISSSRLGPGNYSGRLSLNPGVSVNYEAMQEKLFSLVVLAENTAADNSGNIANVSVLVN 994

Query: 571  VVDVNDNEP-VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629
            ++DVND  P +    L   ++ E+      V  V A+D D   +  +  EL     + GS
Sbjct: 995  ILDVNDEPPTIVPSSLEGVSVRENGTQQDLVHTVFASDRDTN-HSLVFEELSVACYKGGS 1053

Query: 630  ---------FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP---QSSTVIVHIKI 677
                     FV+ P   V+  +  +D E      L     D  T      S    + I+I
Sbjct: 1054 SAGEVCWDWFVLLPNGSVLANSFDIDYELCDVVQLTMRVEDLYTQKGNQYSQNETLQIRI 1113

Query: 678  EDINDSPPVFESDCLTFYI-SENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
             DIND+ PVF     TF +  E SP+   +  ++A D D G    V ++I
Sbjct: 1114 IDINDNAPVFLPVSGTFVVVPEISPVDLQVATVKATDADSGLEGTVFFNI 1163



 Score =  122 bits (293), Expect = 2e-25
 Identities = 165/648 (25%), Positives = 278/648 (42%), Gaps = 85/648 (13%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-LKATDQDIGKNAEVEYTIELVTADT 69
            I+++D NDH P F    Y   V E +  GT + T + A D D G + ++ Y         
Sbjct: 662  IDLIDTNDHIPEFPQSTYNLRVMENSPDGTIIATNITAYDPDSGASGQITYQ-------- 713

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR--ASLDREKVARYTVLVKATDQASPVS 127
            L PE            +Q++F ++  SGA+L R  + LDRE    Y   ++A D  +   
Sbjct: 714  LLPES-----------IQEIFMVNATSGAVLVRNGSLLDREMRPVYYANLQAKDGGN--- 759

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA--NS 185
              +  T  + + ++D NDN P     +Y +SV+E  +V+      +I+A D D     NS
Sbjct: 760  --MMGTTLLEITVLDKNDNEPIIIG-SYFISVEEGQNVS-----TQIRAIDNDEEGTPNS 811

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQ--DGGSPSRSNTT 241
             + + I+ G     F+I   +G++  ++ LD E V   + ++V+  +  D G P  S   
Sbjct: 812  ELGFKIVPGLYSNNFTISQTTGELHNIEPLDREAVDDEAGQMVVTVEVYDHGVPQLSTMV 871

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG-VNAELTYTMTDKD 300
             + I + DVNDN P F    ++ S+ E+   G  +  V A DAD   +N+ +++ +    
Sbjct: 872  NVTITVADVNDNTPVFLQQSYEFSIFESSD-GSFVGDVMATDADRTEINSRISFQLEKS- 929

Query: 301  YTGNVDLPITIDPRSGWVYTSGQLD---------RETQAK-YQLLVTA--TDGGDPPRSA 348
             TG+ +  I+   R G    SG+L             Q K + L+V A  T   +    A
Sbjct: 930  -TGSSNFLIS-SSRLGPGNYSGRLSLNPGVSVNYEAMQEKLFSLVVLAENTAADNSGNIA 987

Query: 349  TATXXXXXXXXXXXXXXFMPGQYE-VELAEDEPPGTPVVTLTATDADEDNRLHYE----- 402
              +               +P   E V + E+      V T+ A+D D ++ L +E     
Sbjct: 988  NVSVLVNILDVNDEPPTIVPSSLEGVSVRENGTQQDLVHTVFASDRDTNHSLVFEELSVA 1047

Query: 403  -ITGGNTRGR----FSITSQNGRGLITVAQPLDFKQERRYVLTVSATD----SGGR-SDT 452
               GG++ G     + +   NG  ++  +  +D++      LT+   D     G + S  
Sbjct: 1048 CYKGGSSAGEVCWDWFVLLPNG-SVLANSFDIDYELCDVVQLTMRVEDLYTQKGNQYSQN 1106

Query: 453  AMVQINITDANNYAPVFENAPYTASVF-EDAPIGTTVLVVSATDSDVGINAQITYSLSSE 511
              +QI I D N+ APVF     T  V  E +P+   V  V ATD+D G+   + +++ S 
Sbjct: 1107 ETLQIRIIDINDNAPVFLPVSGTFVVVPEISPVDLQVATVKATDADSGLEGTVFFNIISV 1166

Query: 512  I--SNEAVAH-HDQQFVI------NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
            +    + V    +  F +      +   G+I     LD      Y +TV ARD   P  +
Sbjct: 1167 VLVQEDGVKRPFENLFKVVTSADQDSYIGSIQVASNLDSSLKGQYQVTVEARDSAAPQQA 1226

Query: 563  DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610
              T + I  VD   +  +  Q + T + ++  L    ++   AT A V
Sbjct: 1227 TQTTLIIFTVD--QSYRIHLQFVTTVDEVQSNLESIRLALTSATKAGV 1272



 Score = 67.3 bits (157), Expect = 6e-09
 Identities = 94/374 (25%), Positives = 162/374 (43%), Gaps = 43/374 (11%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGK-NAEVEYTIELV 65
            ++  I V D ND++PVF  Q YE S+ E +S G+ V  + ATD D  + N+ + + +E  
Sbjct: 871  VNVTITVADVNDNTPVFLQQSYEFSIFE-SSDGSFVGDVMATDADRTEINSRISFQLEKS 929

Query: 66   TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125
            T  +     +               R+    G  +   ++ +EK+  ++++V A + A+ 
Sbjct: 930  TGSSNFLISSSRLGPGNYSG-----RLSLNPGVSVNYEAM-QEKL--FSLVVLAENTAAD 981

Query: 126  VSDRLSSTATIHVNIIDDNDNYPQFSEKTYT-VSVDEDISVTDNPVIAKIKATDADVGAN 184
             S  +++ + + VNI+D ND  P     +   VSV E  + T   ++  + A+D D   +
Sbjct: 982  NSGNIANVSVL-VNILDVNDEPPTIVPSSLEGVSVRE--NGTQQDLVHTVFASDRDTNHS 1038

Query: 185  SAIRYAII----GGNTQMQFSIDSL----SGDVSLVK-TLDYEQVRSYRLVIRAQD---- 231
                   +    GG++  +   D      +G V      +DYE     +L +R +D    
Sbjct: 1039 LVFEELSVACYKGGSSAGEVCWDWFVLLPNGSVLANSFDIDYELCDVVQLTMRVEDLYTQ 1098

Query: 232  -GGSPSRSNTTQLLINIRDVNDNAPRFY-TSLFQESVSENVPIGYSIVRVQAYDADEGVN 289
             G   S++ T Q  I I D+NDNAP F   S     V E  P+   +  V+A DAD G+ 
Sbjct: 1099 KGNQYSQNETLQ--IRIIDINDNAPVFLPVSGTFVVVPEISPVDLQVATVKATDADSGLE 1156

Query: 290  AELTYTMTD---------KDYTGNVDLPITI---DPRSGWVYTSGQLDRETQAKYQLLVT 337
              + + +           K    N+   +T    D   G +  +  LD   + +YQ+ V 
Sbjct: 1157 GTVFFNIISVVLVQEDGVKRPFENLFKVVTSADQDSYIGSIQVASNLDSSLKGQYQVTVE 1216

Query: 338  ATDGGDPPRSATAT 351
            A D   P ++   T
Sbjct: 1217 ARDSAAPQQATQTT 1230



 Score = 44.4 bits (100), Expect = 0.046
 Identities = 47/173 (27%), Positives = 74/173 (42%), Gaps = 11/173 (6%)

Query: 10   QINVLDCNDHSPVF-EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68
            QI ++D ND++PVF  +      V E +     V T+KATD D G    V + I  V   
Sbjct: 1110 QIRIIDINDNAPVFLPVSGTFVVVPEISPVDLQVATVKATDADSGLEGTVFFNIISVV-- 1167

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
             L  ED           V      D   G++   ++LD     +Y V V+A D A+P   
Sbjct: 1168 -LVQEDGVKRPFENLFKVVTSADQDSYIGSIQVASNLDSSLKGQYQVTVEARDSAAP--- 1223

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181
            + ++  T+ +  +D +          +  +VDE  S  ++  +A   AT A V
Sbjct: 1224 QQATQTTLIIFTVDQSYRI----HLQFVTTVDEVQSNLESIRLALTSATKAGV 1272


>UniRef50_UPI0000E80EB1 Cluster: PREDICTED: similar to
           cadherin-related neuronal receptor 3; n=1; Gallus
           gallus|Rep: PREDICTED: similar to cadherin-related
           neuronal receptor 3 - Gallus gallus
          Length = 695

 Score =  230 bits (563), Expect = 4e-58
 Identities = 191/627 (30%), Positives = 294/627 (46%), Gaps = 55/627 (8%)

Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDG-GSPS 236
           + G   A R  ++    +    +   SG + +   LD E++  +S    +R +     P 
Sbjct: 53  EAGEAEARRLRLVARGRRASVEVSGASGALVVSSRLDREELCGKSAPCALRLEVLLDRPL 112

Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
           R     + + + D+NDNAPRF  +    SV EN P+        A DAD G NA+L+Y++
Sbjct: 113 R--VFHVEVEVTDINDNAPRFPNAYKNISVWENSPLNSRFPLEGASDADIGSNAQLSYSL 170

Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
           +  ++          +  S ++  +  LDRE+ ++++L++TA+DGG P  + T       
Sbjct: 171 SPSEHFALDVQRGEENLESLFLVLTKPLDRESLSEHRLVLTASDGGRPALTGTVQLVISV 230

Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGG---NTRGR 411
                    F    Y+V+L ED   GT V  + ATD DE  +    Y I      + R  
Sbjct: 231 LDANDNAPQFNQSVYKVQLPEDAAEGTLVGRVAATDPDEGINQEFSYSIVSSVPASQRDS 290

Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN 471
           FSI  + G   I +   LD++  R   L + A D+G                 + P+  +
Sbjct: 291 FSIDPRTGE--IRLRGLLDYEVVRLCELQIEARDNG-----------------FPPLSRH 331

Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
                 V +            A+D+D+G NAQ++YSLS    +E  A   +    N ++ 
Sbjct: 332 CKVVVQVLD-----------GASDADIGSNAQLSYSLSP---SEHFALDVKSPDDNLKSL 377

Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
            +     LDRE++S + L +TA DGG P+L+ T  + ISV+D NDN P F Q +Y   + 
Sbjct: 378 FLVLTHPLDRESLSEHRLVLTASDGGRPALTGTVQLVISVLDANDNAPQFNQSVYKVQLP 437

Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRES 649
           EDA  GT V +V ATD D G+N    Y +       +  SF IDP +G IR    LD E 
Sbjct: 438 EDAAEGTLVGRVAATDPDEGINQAFSYSIVSSVPASQRDSFSIDPRTGEIRLTGPLDFED 497

Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
           V  H+L+  A D GTPP S    V +++ D+ND+ P      L+  + E++ +GT +  +
Sbjct: 498 VHQHELQIEARDKGTPPLSGHCSVILEVLDVNDNAPEVWVTSLSVPVPEDAALGTVVALL 557

Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSL-ETRQGSDKAELVTMVDLDYESPRKKYELVIR 768
              D D GPN  V  +++     + F L  T  GS    LV    LD E    +YE+ + 
Sbjct: 558 SVSDRDSGPNGRVRCAVR---PPSPFGLVATFAGS--YSLVLREALDRERV-SEYEVEVG 611

Query: 769 A---ASPPLWNDVRVEILVTDVNDNAP 792
           A    +PPL     + + V+DVNDNAP
Sbjct: 612 AEDGGAPPLRASRGLRVPVSDVNDNAP 638



 Score =  217 bits (530), Expect = 4e-54
 Identities = 176/632 (27%), Positives = 284/632 (44%), Gaps = 69/632 (10%)

Query: 8   HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
           H ++ V D ND++P F       SV E +   +      A+D DIG NA++ Y++     
Sbjct: 116 HVEVEVTDINDNAPRFPNAYKNISVWENSPLNSRFPLEGASDADIGSNAQLSYSLS---- 171

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
                E            ++ +F +       LT+  LDRE ++ + +++ A+D   P  
Sbjct: 172 ---PSEHFALDVQRGEENLESLFLV-------LTK-PLDRESLSEHRLVLTASDGGRPA- 219

Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
             L+ T  + ++++D NDN PQF++  Y V + ED    +  ++ ++ ATD D G N   
Sbjct: 220 --LTGTVQLVISVLDANDNAPQFNQSVYKVQLPED--AAEGTLVGRVAATDPDEGINQEF 275

Query: 188 RYAIIGGNTQMQ---FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
            Y+I+      Q   FSID  +G++ L   LDYE VR   L I A+D G P  S   +++
Sbjct: 276 SYSIVSSVPASQRDSFSIDPRTGEIRLRGLLDYEVVRLCELQIEARDNGFPPLSRHCKVV 335

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           + + D   +A           +  N  + YS+   + +  D             K    N
Sbjct: 336 VQVLDGASDA----------DIGSNAQLSYSLSPSEHFALDV------------KSPDDN 373

Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
           +        +S ++  +  LDRE+ ++++L++TA+DGG P  + T               
Sbjct: 374 L--------KSLFLVLTHPLDRESLSEHRLVLTASDGGRPALTGTVQLVISVLDANDNAP 425

Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITG---GNTRGRFSITSQNG 419
            F    Y+V+L ED   GT V  + ATD DE  +    Y I      + R  FSI  + G
Sbjct: 426 QFNQSVYKVQLPEDAAEGTLVGRVAATDPDEGINQAFSYSIVSSVPASQRDSFSIDPRTG 485

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477
              I +  PLDF+   ++ L + A D G    S    V + + D N+ AP       +  
Sbjct: 486 E--IRLTGPLDFEDVHQHELQIEARDKGTPPLSGHCSVILEVLDVNDNAPEVWVTSLSVP 543

Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
           V EDA +GT V ++S +D D G N ++  ++        VA     +       ++   +
Sbjct: 544 VPEDAALGTVVALLSVSDRDSGPNGRVRCAVRPPSPFGLVATFAGSY-------SLVLRE 596

Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
            LDRE +S Y + V A DGG P L  +  + + V DVNDN P F Q +YT    E+   G
Sbjct: 597 ALDRERVSEYEVEVGAEDGGAPPLRASRGLRVPVSDVNDNAPAFAQAVYTVLARENNAAG 656

Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGS 629
             ++++ A D D   NGR+ Y +       GS
Sbjct: 657 AELARLWARDPDEAGNGRVSYSVAEGGAGSGS 688



 Score =  175 bits (425), Expect = 2e-41
 Identities = 110/315 (34%), Positives = 161/315 (51%), Gaps = 8/315 (2%)

Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ--INITDANNYAPVFENAPYTASVFE 480
           + +  PLD +    + L ++A+D G  + T  VQ  I++ DAN+ AP F  + Y   + E
Sbjct: 379 LVLTHPLDRESLSEHRLVLTASDGGRPALTGTVQLVISVLDANDNAPQFNQSVYKVQLPE 438

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           DA  GT V  V+ATD D GIN   +YS+ S +     A     F I+P+TG I     LD
Sbjct: 439 DAAEGTLVGRVAATDPDEGINQAFSYSIVSSVP----ASQRDSFSIDPRTGEIRLTGPLD 494

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
            E +  + L + ARD G P LS    V + V+DVNDN P       +  + EDA +GT V
Sbjct: 495 FEDVHQHELQIEARDKGTPPLSGHCSVILEVLDVNDNAPEVWVTSLSVPVPEDAALGTVV 554

Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
           + +  +D D G NGR+   + P     G       S  +   +ALDRE V+ ++++  A 
Sbjct: 555 ALLSVSDRDSGPNGRVRCAVRPPS-PFGLVATFAGSYSLVLREALDRERVSEYEVEVGAE 613

Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
           DGG PP  ++  + + + D+ND+ P F     T    EN+  G  +  + A DPDE  N 
Sbjct: 614 DGGAPPLRASRGLRVPVSDVNDNAPAFAQAVYTVLARENNAAGAELARLWARDPDEAGNG 673

Query: 721 VVHYSI-KGGDDSNS 734
            V YS+ +GG  S S
Sbjct: 674 RVSYSVAEGGAGSGS 688



 Score =  134 bits (324), Expect = 3e-29
 Identities = 86/263 (32%), Positives = 136/263 (51%), Gaps = 15/263 (5%)

Query: 92  IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151
           + G SGAL+  + LDRE++   +       +   + DR      + V + D NDN P+F 
Sbjct: 75  VSGASGALVVSSRLDREELCGKSA--PCALRLEVLLDRPLRVFHVEVEVTDINDNAPRFP 132

Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSL 211
                +SV E+  +  N       A+DAD+G+N+ + Y++   +    F++D   G+ +L
Sbjct: 133 NAYKNISVWENSPL--NSRFPLEGASDADIGSNAQLSYSL---SPSEHFALDVQRGEENL 187

Query: 212 -------VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
                   K LD E +  +RLV+ A DGG P+ + T QL+I++ D NDNAP+F  S+++ 
Sbjct: 188 ESLFLVLTKPLDRESLSEHRLVLTASDGGRPALTGTVQLVISVLDANDNAPQFNQSVYKV 247

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
            + E+   G  + RV A D DEG+N E +Y++         D   +IDPR+G +   G L
Sbjct: 248 QLPEDAAEGTLVGRVAATDPDEGINQEFSYSIVSSVPASQRD-SFSIDPRTGEIRLRGLL 306

Query: 325 DRETQAKYQLLVTATDGGDPPRS 347
           D E     +L + A D G PP S
Sbjct: 307 DYEVVRLCELQIEARDNGFPPLS 329



 Score =  118 bits (283), Expect = 3e-24
 Identities = 103/341 (30%), Positives = 155/341 (45%), Gaps = 31/341 (9%)

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV-INPQTGAITT 535
           SV E+A  GT   VV     D+G+ A    +    +    VA   +  V ++  +GA+  
Sbjct: 32  SVPEEAEAGT---VVGRLAQDLGLEAGEAEARRLRL----VARGRRASVEVSGASGALVV 84

Query: 536 NKLLDRETMSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
           +  LDRE + G       R +  +        VE+ V D+NDN P F       ++ E++
Sbjct: 85  SSRLDREELCGKSAPCALRLEVLLDRPLRVFHVEVEVTDINDNAPRFPNAYKNISVWENS 144

Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG-------VIRTNKALDR 647
            + +     GA+DAD+G N ++ Y L P +     F +D   G        +   K LDR
Sbjct: 145 PLNSRFPLEGASDADIGSNAQLSYSLSPSEH----FALDVQRGEENLESLFLVLTKPLDR 200

Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
           ES++ H L   A DGG P  + TV + I + D ND+ P F        + E++  GT +G
Sbjct: 201 ESLSEHRLVLTASDGGRPALTGTVQLVISVLDANDNAPQFNQSVYKVQLPEDAAEGTLVG 260

Query: 708 EIRAHDPDEGPNAVVHYSIKG---GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764
            + A DPDEG N    YSI         +SFS++ R G    E+     LDYE  R   E
Sbjct: 261 RVAATDPDEGINQEFSYSIVSSVPASQRDSFSIDPRTG----EIRLRGLLDYEVVR-LCE 315

Query: 765 LVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFN 802
           L I A     PPL    +V + V D   +A +  + Q+ ++
Sbjct: 316 LQIEARDNGFPPLSRHCKVVVQVLDGASDADIGSNAQLSYS 356


>UniRef50_Q60H55 Cluster: Protocadherin2-gamma-v12-sCP1; n=8; Danio
           rerio|Rep: Protocadherin2-gamma-v12-sCP1 - Danio rerio
           (Zebrafish) (Brachydanio rerio)
          Length = 955

 Score =  230 bits (562), Expect = 5e-58
 Identities = 173/606 (28%), Positives = 284/606 (46%), Gaps = 26/606 (4%)

Query: 88  DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
           +   ++  +G LL +  +DRE +   T       Q   + D      TI V I D NDN 
Sbjct: 69  EYIELNRNTGLLLIKEKMDRESLCAKTTPCALHLQM--ILDNPMELYTITVEITDINDNA 126

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNT---QMQFSID- 203
           P F ++ +   + E   V    ++ K  A D DVG NS   Y++   +    ++Q   D 
Sbjct: 127 PNFQKRDFKFEISESAMVGARFMLGK--AFDPDVGTNSLQSYSLKPTDKFRLELQSQADG 184

Query: 204 SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263
           S + ++ L K LD E   S+ L++ A DGG P  S T Q+ I + D+NDNAP F    ++
Sbjct: 185 SKNVEMILQKALDREMQSSFTLLLEAFDGGDPVLSGTVQIHIAVLDINDNAPVFMQKEYK 244

Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323
            + +E  P G  +  V A D DEG N+E+TY ++D   +   D+   ++ ++G +  +G 
Sbjct: 245 ATATEEAPKGSILTVVSATDTDEGSNSEVTYYISDTMDSVMADM-FLVNEQTGELILNGH 303

Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383
            D E  + Y+L + A D G    +                   +   + V  +E    GT
Sbjct: 304 FDYEKVSHYELTIHAKDQGGLSNACKVIIDVLDVNDNSPSINILSSSHSV--SEGSKFGT 361

Query: 384 PVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL-ITVAQPLDFKQERRYVLTVS 442
            +  L   D D       +    +    F I SQ+     +   Q LD ++E  Y ++V 
Sbjct: 362 VIAMLNVDDLDSGASGQVQCV-MSEEIPFVIKSQSSNFFSLQTEQELDRERETEYNISVI 420

Query: 443 ATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
            +D G    S +  + + I+D N+  PVF+ + Y A V E+   G ++  V A+D+D   
Sbjct: 421 CSDEGVPSLSSSVSLTVQISDVNDNPPVFKKSNYEAFVMENNTPGLSIFTVKASDADWNQ 480

Query: 501 NAQITYSL-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
           NA+++Y L  S +S  +V+ +     ++P +G IT  +  D ET+  +   V A+DGG P
Sbjct: 481 NARVSYILEDSTVSGVSVSSY---VSVHPDSGLITAVRSFDYETLKDFHFRVKAQDGGSP 537

Query: 560 SLSDTTDVEISVVDVNDNEP--VFKQQLYTANIME----DALVGTSVSQVGATDADVGLN 613
            LS    V+++V D NDN P  ++  Q  T+ + E     A VG  V++V A D D G N
Sbjct: 538 PLSSNVTVKVTVQDQNDNAPQVLYPVQTGTSVVAEIVPRAADVGYLVTKVVAVDVDSGQN 597

Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673
             + Y+L  K  +   F +   +G IRT + +  +      L  V  D G P +S+ V +
Sbjct: 598 AWLSYKLQ-KAPDRALFEVGLQNGEIRTVRQVTDKDAVKQKLTVVVEDNGQPSRSAVVSI 656

Query: 674 HIKIED 679
           ++ + D
Sbjct: 657 NVAVAD 662



 Score =  229 bits (561), Expect = 6e-58
 Identities = 168/574 (29%), Positives = 277/574 (48%), Gaps = 36/574 (6%)

Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302
           + + I D+NDNAP F    F+  +SE+  +G   +  +A+D D G N+  +Y++   D  
Sbjct: 115 ITVEITDINDNAPNFQKRDFKFEISESAMVGARFMLGKAFDPDVGTNSLQSYSLKPTDKF 174

Query: 303 GNVDLPITID-PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
             ++L    D  ++  +     LDRE Q+ + LL+ A DGGDP  S T            
Sbjct: 175 -RLELQSQADGSKNVEMILQKALDREMQSSFTLLLEAFDGGDPVLSGTVQIHIAVLDIND 233

Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITG---GNTRGRFSITS 416
               FM  +Y+    E+ P G+ +  ++ATD DE  ++ + Y I+          F +  
Sbjct: 234 NAPVFMQKEYKATATEEAPKGSILTVVSATDTDEGSNSEVTYYISDTMDSVMADMFLVNE 293

Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA 476
           Q G  ++      D+++   Y LT+ A D GG S+   V I++ D N+ +P       + 
Sbjct: 294 QTGELILN--GHFDYEKVSHYELTIHAKDQGGLSNACKVIIDVLDVNDNSPSINILSSSH 351

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG---AI 533
           SV E +  GT + +++  D D G + Q+   +S EI           FVI  Q+    ++
Sbjct: 352 SVSEGSKFGTVIAMLNVDDLDSGASGQVQCVMSEEIP----------FVIKSQSSNFFSL 401

Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593
            T + LDRE  + Y ++V   D GVPSLS +  + + + DVNDN PVFK+  Y A +ME+
Sbjct: 402 QTEQELDRERETEYNISVICSDEGVPSLSSSVSLTVQISDVNDNPPVFKKSNYEAFVMEN 461

Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDP---KDREEGSFV-IDPASGVIRTNKALDRES 649
              G S+  V A+DAD   N R+ Y L+          S+V + P SG+I   ++ D E+
Sbjct: 462 NTPGLSIFTVKASDADWNQNARVSYILEDSTVSGVSVSSYVSVHPDSGLITAVRSFDYET 521

Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP--VFESDCLTFYISENSP----IG 703
           +     +  A DGG+PP SS V V + ++D ND+ P  ++     T  ++E  P    +G
Sbjct: 522 LKDFHFRVKAQDGGSPPLSSNVTVKVTVQDQNDNAPQVLYPVQTGTSVVAEIVPRAADVG 581

Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY 763
             + ++ A D D G NA + Y ++   D   F +  + G  +   V  V  D ++ ++K 
Sbjct: 582 YLVTKVVAVDVDSGQNAWLSYKLQKAPDRALFEVGLQNG--EIRTVRQV-TDKDAVKQKL 638

Query: 764 ELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDF 797
            +V+     P  + V V I V   +    V+ +F
Sbjct: 639 TVVVEDNGQPSRSAV-VSINVAVADSFPEVLSEF 671



 Score =  200 bits (487), Expect = 6e-49
 Identities = 162/585 (27%), Positives = 265/585 (45%), Gaps = 61/585 (10%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + + D ND++P F+ + ++  + E A  G   +  KA D D+G N+   Y        +L
Sbjct: 117 VEITDINDNAPNFQKRDFKFEISESAMVGARFMLGKAFDPDVGTNSLQSY--------SL 168

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            P D                + DG ++  ++ + +LDRE  + +T+L++A D   PV   
Sbjct: 169 KPTDKFRLELQS--------QADGSKNVEMILQKALDREMQSSFTLLLEAFDGGDPV--- 217

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           LS T  IH+ ++D NDN P F +K Y  +  E+       ++  + ATD D G+NS + Y
Sbjct: 218 LSGTVQIHIAVLDINDNAPVFMQKEYKATATEE--APKGSILTVVSATDTDEGSNSEVTY 275

Query: 190 AIIGGNTQM---QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            I      +    F ++  +G++ L    DYE+V  Y L I A+D G    SN  +++I+
Sbjct: 276 YISDTMDSVMADMFLVNEQTGELILNGHFDYEKVSHYELTIHAKDQG--GLSNACKVIID 333

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
           + DVNDN+P         SVSE    G  I  +   D D G + ++   M++       +
Sbjct: 334 VLDVNDNSPSINILSSSHSVSEGSKFGTVIAMLNVDDLDSGASGQVQCVMSE-------E 386

Query: 307 LPITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
           +P  I  +S   +   T  +LDRE + +Y + V  +D G P  S++ +            
Sbjct: 387 IPFVIKSQSSNFFSLQTEQELDRERETEYNISVICSDEGVPSLSSSVSLTVQISDVNDNP 446

Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITS----Q 417
             F    YE  + E+  PG  + T+ A+DAD  ++ R+ Y +      G  S++S     
Sbjct: 447 PVFKKSNYEAFVMENNTPGLSIFTVKASDADWNQNARVSYILEDSTVSG-VSVSSYVSVH 505

Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAP--VFENAP 473
              GLIT  +  D++  + +   V A D G    S    V++ + D N+ AP  ++    
Sbjct: 506 PDSGLITAVRSFDYETLKDFHFRVKAQDGGSPPLSSNVTVKVTVQDQNDNAPQVLYPVQT 565

Query: 474 YTASVFEDAP----IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
            T+ V E  P    +G  V  V A D D G NA ++Y L         A     F +  Q
Sbjct: 566 GTSVVAEIVPRAADVGYLVTKVVAVDVDSGQNAWLSYKLQK-------APDRALFEVGLQ 618

Query: 530 TGAI-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
            G I T  ++ D++ +    LTV   D G PS S    + ++V D
Sbjct: 619 NGEIRTVRQVTDKDAVK-QKLTVVVEDNGQPSRSAVVSINVAVAD 662



 Score =  184 bits (448), Expect = 3e-44
 Identities = 143/470 (30%), Positives = 222/470 (47%), Gaps = 40/470 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I VLD ND++PVF  ++Y+A+  E A  G+ +  + ATD D G N+EV Y I    +DT+
Sbjct: 226 IAVLDINDNAPVFMQKEYKATATEEAPKGSILTVVSATDTDEGSNSEVTYYI----SDTM 281

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           +              + D+F ++ ++G L+     D EKV+ Y + + A DQ       L
Sbjct: 282 D------------SVMADMFLVNEQTGELILNGHFDYEKVSHYELTIHAKDQGG-----L 324

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           S+   + ++++D NDN P  +  + + SV E        VIA +   D D GA+  ++  
Sbjct: 325 SNACKVIIDVLDVNDNSPSINILSSSHSVSEGSKF--GTVIAMLNVDDLDSGASGQVQCV 382

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
           +   + ++ F I S S +   ++T   LD E+   Y + +   D G PS S++  L + I
Sbjct: 383 M---SEEIPFVIKSQSSNFFSLQTEQELDRERETEYNISVICSDEGVPSLSSSVSLTVQI 439

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NVD 306
            DVNDN P F  S ++  V EN   G SI  V+A DAD   NA ++Y + D   +G +V 
Sbjct: 440 SDVNDNPPVFKKSNYEAFVMENNTPGLSIFTVKASDADWNQNARVSYILEDSTVSGVSVS 499

Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
             +++ P SG +      D ET   +   V A DGG PP S+  T               
Sbjct: 500 SYVSVHPDSGLITAVRSFDYETLKDFHFRVKAQDGGSPPLSSNVTVKVTVQDQNDNAPQV 559

Query: 367 M-PGQYEVELAEDEPP-----GTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQN 418
           + P Q    +  +  P     G  V  + A D D      L Y++     R  F +  QN
Sbjct: 560 LYPVQTGTSVVAEIVPRAADVGYLVTKVVAVDVDSGQNAWLSYKLQKAPDRALFEVGLQN 619

Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468
           G  + TV Q  D K   +  LTV   D+G  S +A+V IN+  A+++  V
Sbjct: 620 GE-IRTVRQVTD-KDAVKQKLTVVVEDNGQPSRSAVVSINVAVADSFPEV 667


>UniRef50_UPI0000DB7673 Cluster: PREDICTED: similar to Cad74A
            CG6445-PA, isoform A; n=2; Apocrita|Rep: PREDICTED:
            similar to Cad74A CG6445-PA, isoform A - Apis mellifera
          Length = 1843

 Score =  229 bits (560), Expect = 8e-58
 Identities = 251/899 (27%), Positives = 393/899 (43%), Gaps = 93/899 (10%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD--IGKNAEVEYTIELVTAD 68
            I + D ND+ P FE ++Y  +VREGA+S    + ++ATD D  +  N +V Y+I    + 
Sbjct: 583  IELEDVNDNKPAFEQKEYTRTVREGATSFDPQMFVRATDADGPMQGNGKVTYSISSHNSM 642

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR--YTVLVKATDQASPV 126
            T                  DVF+I+  +G +    ++  +   R  Y + ++ATD  +P 
Sbjct: 643  T-----------------NDVFKINRDTGEVTMAKAVRSDDTERGIYELAIRATDAGTPP 685

Query: 127  ---SDRLSSTATIHVN---IIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD 180
                 RLS    +  N   I   N         TY   + E+ S      + ++ A D D
Sbjct: 686  LFSETRLSVRVGVPGNQKPIFRGNYKSNLPGPSTYRARLLENAS--PGTEVIRVVANDPD 743

Query: 181  VGANSAIRYAIIGGNTQMQFSIDSLSG--DVSLVKTLDYEQV-RSYRLVIRAQDGGSPSR 237
             G +S ++Y I  G  +  F IDS SG   VS    LD E     Y +++ A D G+P R
Sbjct: 744  -GRDSLLQYHIASG-AKDNFVIDSSSGVITVSPDARLDLESGGEKYEVIVYAIDSGTPVR 801

Query: 238  SN-TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
               TT + +N+ DVN+  P F  S +   VSE   IG  +++V A D D   +A L Y++
Sbjct: 802  ETATTTVTVNMIDVNNKPPTFNESTYLVYVSERAAIGEPVLKVAATDPDS--DAYLEYSI 859

Query: 297  TDK----DYTG---------NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG- 342
             +     D TG         +      I+  +G +  +  LD +  A   L V   D   
Sbjct: 860  VEPIRAVDKTGVALKNTAPYDYKTAFRINSTTGLITVNRVLDYQVAAVVILTVQVQDLNA 919

Query: 343  --DPPRSATATXXXXXXXXXXXXXXFM--PG------QYEVELAEDEPPGTPVVTLTATD 392
              D  R  T                    PG         + + E++P GT ++ L+A +
Sbjct: 920  VVDKERQITRVEVTIYIQAYSDDNPTFTNPGWSPNNPTIRISVPEEQPLGTTLLMLSARE 979

Query: 393  ADEDNRLH-YEITG-GNTRGRFSITSQNGRGLITVAQPLDFKQ-ERRYV---LTVSATDS 446
                  +  +E+    +  G  ++  Q+G   + +++ LD++   ++++   +   A D 
Sbjct: 980  PTTGYPVQRFELVREDDDEGYVNVGVQSGN--VVLSKRLDYEALNQKFIQFKVRALARDY 1037

Query: 447  G--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504
                +   A V + + D N+  PVF    Y  SV E       VL V ATD D     Q 
Sbjct: 1038 EITRKMSEANVIVEVQDTNDNNPVFAQKDYKISVLESEKPSKIVLNVKATDMDSSNTEQE 1097

Query: 505  TYSLSSEISNEAVAHHDQQFVINPQTG--AITTNKLLDRETMSGYLLTVTARD---GGVP 559
                  E+    +  +   F + P TG   I TN  LDRE  S     V A D   GG  
Sbjct: 1098 VRRGYGEVRYSLIGENANMFEVEPITGNIQIATNTTLDREKQSVLRFYVVASDMPQGGAE 1157

Query: 560  SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619
              S    V + V+DVNDN P F+Q+ YTA I E+A  G SV  + ATD D    G I+YE
Sbjct: 1158 QRSTRALVTVDVLDVNDNAPTFEQEAYTAVIPENAPSGVSVVNITATDPDEDKGGVINYE 1217

Query: 620  LDPKDREEGSFVIDPASGVIRTNKAL-DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678
            +  +    G F ID  +G I + +AL  +     + ++    DGG P   S VI+ + I 
Sbjct: 1218 IIDEGEASGLFEIDHKTGEIYSARALTGKGRTEPYIMRIRGEDGGEPELYSDVILTLYIG 1277

Query: 679  DI--NDSPPVFESDCL--TFYISENSPIGTTIGEIRAHDPDEG--PNAVVHYSIKGGDDS 732
            D+  ND  P+F    L    YISENS IG+ + ++ A DPD+   PN  + +      + 
Sbjct: 1278 DVVSNDGVPLFIRPTLEEVAYISENSTIGSPVFQVVASDPDDPNLPNGKITFKFLEDGNF 1337

Query: 733  NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVND 789
               +   R  S+   + T   LD E+ +  Y L++ A    +PP      ++++V D++D
Sbjct: 1338 GKDASAFRINSETGLITTRKLLDREA-KDSYTLILVAQDLGNPPQQATRVLQVIVNDIDD 1396

Query: 790  NAPVMK---DFQIIFNNYKDCFPVG-PFGRVPAYDADVTDK--LQYRILSGNNANLILL 842
            + P  K   D   +     +  P+G   G + A D D+ +   + Y I+ GN A L L+
Sbjct: 1397 HKPHFKRNLDSPPVELAVLEETPIGAKVGVIEAIDEDIGENGMIDYAIVYGNEAGLFLV 1455



 Score =  221 bits (541), Expect = 2e-55
 Identities = 239/846 (28%), Positives = 397/846 (46%), Gaps = 118/846 (13%)

Query: 28   YEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQ 87
            Y A + E AS GT V+ + A D D G+++ ++Y I                        +
Sbjct: 720  YRARLLENASPGTEVIRVVANDPD-GRDSLLQYHI--------------------ASGAK 758

Query: 88   DVFRIDGRSGALLTR--ASLDREKVA-RYTVLVKATDQASPVSDRLSSTATIHVNIIDDN 144
            D F ID  SG +     A LD E    +Y V+V A D  +PV  R ++T T+ VN+ID N
Sbjct: 759  DNFVIDSSSGVITVSPDARLDLESGGEKYEVIVYAIDSGTPV--RETATTTVTVNMIDVN 816

Query: 145  DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG---------- 194
            +  P F+E TY V V E  ++ + PV+ K+ ATD D  +++ + Y+I+            
Sbjct: 817  NKPPTFNESTYLVYVSERAAIGE-PVL-KVAATDPD--SDAYLEYSIVEPIRAVDKTGVA 872

Query: 195  --NT-----QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS---PSRSNT-TQL 243
              NT     +  F I+S +G +++ + LDY+      L ++ QD  +     R  T  ++
Sbjct: 873  LKNTAPYDYKTAFRINSTTGLITVNRVLDYQVAAVVILTVQVQDLNAVVDKERQITRVEV 932

Query: 244  LINIRDVNDNAPRFYTS-------LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
             I I+  +D+ P F            + SV E  P+G +++ + A +   G   +    +
Sbjct: 933  TIYIQAYSDDNPTFTNPGWSPNNPTIRISVPEEQPLGTTLLMLSAREPTTGYPVQRFELV 992

Query: 297  TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ----AKYQLLVTATDGGDPPRSATATX 352
             + D  G V++ +    +SG V  S +LD E       ++++   A D     + + A  
Sbjct: 993  REDDDEGYVNVGV----QSGNVVLSKRLDYEALNQKFIQFKVRALARDYEITRKMSEANV 1048

Query: 353  XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRF 412
                         F    Y++ + E E P   V+ + ATD D  N    E+  G    R+
Sbjct: 1049 IVEVQDTNDNNPVFAQKDYKISVLESEKPSKIVLNVKATDMDSSNT-EQEVRRGYGEVRY 1107

Query: 413  SITSQNGR--------GLITVAQPLDFKQERRYVLT--VSATD--SGG---RSDTAMVQI 457
            S+  +N          G I +A      +E++ VL   V A+D   GG   RS  A+V +
Sbjct: 1108 SLIGENANMFEVEPITGNIQIATNTTLDREKQSVLRFYVVASDMPQGGAEQRSTRALVTV 1167

Query: 458  NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517
            ++ D N+ AP FE   YTA + E+AP G +V+ ++ATD D      I Y    EI +E  
Sbjct: 1168 DVLDVNDNAPTFEQEAYTAVIPENAPSGVSVVNITATDPDEDKGGVINY----EIIDEGE 1223

Query: 518  AHHDQQFVINPQTGAI-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV-- 574
            A     F I+ +TG I +   L  +     Y++ +   DGG P L     + + + DV  
Sbjct: 1224 A--SGLFEIDHKTGEIYSARALTGKGRTEPYIMRIRGEDGGEPELYSDVILTLYIGDVVS 1281

Query: 575  NDNEPVFKQQLY--TANIMEDALVGTSVSQVGATDAD-VGL-NGRIHYE-LDPKD--REE 627
            ND  P+F +      A I E++ +G+ V QV A+D D   L NG+I ++ L+  +  ++ 
Sbjct: 1282 NDGVPLFIRPTLEEVAYISENSTIGSPVFQVVASDPDDPNLPNGKITFKFLEDGNFGKDA 1341

Query: 628  GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687
             +F I+  +G+I T K LDRE+  ++ L  VA D G PPQ +T ++ + + DI+D  P F
Sbjct: 1342 SAFRINSETGLITTRKLLDREAKDSYTLILVAQDLGNPPQQATRVLQVIVNDIDDHKPHF 1401

Query: 688  ----ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLET---- 739
                +S  +   + E +PIG  +G I A D D G N ++ Y+I  G+++  F +E     
Sbjct: 1402 KRNLDSPPVELAVLEETPIGAKVGVIEAIDEDIGENGMIDYAIVYGNEAGLFLVERLENN 1461

Query: 740  --------RQGSDKAE--LVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVND 789
                    R   ++A+  L+T+    Y +  KK ++V +  +    ++ +V + V D++D
Sbjct: 1462 SAVIRSNGRLDRERADHHLLTIKCFPYST--KKGDIVPKPYNRQDPSERQVLVKVLDIDD 1519

Query: 790  NAPVMK 795
            N P  K
Sbjct: 1520 NRPKFK 1525



 Score =  213 bits (520), Expect = 6e-53
 Identities = 213/808 (26%), Positives = 351/808 (43%), Gaps = 78/808 (9%)

Query: 88  DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
           + F ++  SG ++ R +LDRE      V++  TD+    S+  + +    + ++D+NDN 
Sbjct: 68  EYFTVNRDSGVVVLRKALDRESQDLIEVIISITDEGIAGSEPNTVSLRREIAVLDENDNP 127

Query: 148 PQFSEKTYTVSVDEDISVTDNPV-IAKIKATDADVGANSAIRYAIIGGNTQ------MQF 200
           P +  + Y   V E   V    V    I  TD D G N+ +    +  +           
Sbjct: 128 PVYHGRPYAARVPESAHVGGLLVPPGTITITDRDGGVNADVHVECVSASRDDDVCDVFNV 187

Query: 201 SIDSLSG-----DVSLVKTLDYEQVRSYRLVIRAQDGGSP-SR--SNTTQLLINIRDVND 252
           S + L+       +SL K+LDYE+  SY + + A DG S  SR       + +++ DV D
Sbjct: 188 STEKLAEGKYDVQISLAKSLDYERRNSYLINLLAIDGASDVSRRLQARATVAVDVLDVQD 247

Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI- 311
             P F  + +  ++ EN   G++I+ V+A D D G    L  T+ D+D +G+ DL ++  
Sbjct: 248 QPPVFLNAPYSAALPENTAAGHTILTVRARDGDTGEPRSLLLTLEDED-SGHFDLDVSRE 306

Query: 312 -DPRSG-WVYTSGQLDRE------TQAKYQLLVTATD---GGDPPRSATATXXXXXXXXX 360
            D   G  V T+  LDRE          Y   V AT+      P  +AT+          
Sbjct: 307 GDATVGKLVTTNVSLDREDPRILQNGGIYTFQVKATELINNEIPAETATSIVTIVVTDVD 366

Query: 361 XXXXXFMPGQYEVELAEDEPPGTPV--VTLTATDADEDNRLHYEITGGNTRG------RF 412
                F    + + ++ED    TP+  + +  +D D      Y +   +  G       F
Sbjct: 367 DLMPVFNQKYFNITISEDIGKDTPLPGLNMIVSDGDVGENAKYTLALRDDPGYPGISRAF 426

Query: 413 SITSQNGRGLITV------AQPLDFKQE----RRYVLTVSATDSGGRSDTAMVQINITDA 462
            +  +  +G + V         LD+  E    R+    V A  +     ++ V + + DA
Sbjct: 427 VVGPEEAQGRVPVVVKARNVSVLDYDVEDIARRQLEFEVVALVANQVVASSRVHVRLKDA 486

Query: 463 NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522
           N+++P F  + Y  S+ EDA IGT    V A D D G   ++TY+L              
Sbjct: 487 NDHSPEFSQSVYKLSLPEDAGIGTRFGDVFARDYDSGSFGELTYTLR--------GFGAD 538

Query: 523 QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582
           +F  NP+TG I+ +K LD E    Y LT+ A+DGG        ++ I + DVNDN+P F+
Sbjct: 539 KFATNPKTGGISVSKALDYEAQKSYSLTMEAKDGG--GRVSAVNILIELEDVNDNKPAFE 596

Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGL--NGRIHYELDPKDREEGS-FVIDPASGVI 639
           Q+ YT  + E A        V ATDAD  +  NG++ Y +   +      F I+  +G +
Sbjct: 597 QKEYTRTVREGATSFDPQMFVRATDADGPMQGNGKVTYSISSHNSMTNDVFKINRDTGEV 656

Query: 640 RTNKAL--DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD------- 690
              KA+  D      ++L   A D GTPP  S   + +++    +  P+F  +       
Sbjct: 657 TMAKAVRSDDTERGIYELAIRATDAGTPPLFSETRLSVRVGVPGNQKPIFRGNYKSNLPG 716

Query: 691 --CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAEL 748
                  + EN+  GT +  + A+DPD G ++++ Y I  G   N F +++  G     +
Sbjct: 717 PSTYRARLLENASPGTEVIRVVANDPD-GRDSLLQYHIASGAKDN-FVIDSSSG--VITV 772

Query: 749 VTMVDLDYESPRKKYELVIRA--ASPPLWNDVRVEILVT--DVNDNAPVMKDFQIIFNNY 804
                LD ES  +KYE+++ A  +  P+       + V   DVN+  P   +   +    
Sbjct: 773 SPDARLDLESGGEKYEVIVYAIDSGTPVRETATTTVTVNMIDVNNKPPTFNESTYLVYVS 832

Query: 805 KDCFPVGPFGRVPAYDADVTDKLQYRIL 832
           +      P  +V A D D    L+Y I+
Sbjct: 833 ERAAIGEPVLKVAATDPDSDAYLEYSIV 860



 Score =  213 bits (520), Expect = 6e-53
 Identities = 214/771 (27%), Positives = 347/771 (45%), Gaps = 76/771 (9%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVL---TLKATDQDIGKNAEVEYTIE 63
           + ++I VLD ND+ PV+  + Y A V E A  G  ++   T+  TD+D G NA+V   +E
Sbjct: 114 LRREIAVLDENDNPPVYHGRPYAARVPESAHVGGLLVPPGTITITDRDGGVNADVH--VE 171

Query: 64  LVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRA-SLDREKVARYTVLVKATDQ 122
            V+A     +D           +      +G+    ++ A SLD E+   Y + + A D 
Sbjct: 172 CVSAS--RDDDVCDVFNVSTEKL-----AEGKYDVQISLAKSLDYERRNSYLINLLAIDG 224

Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
           AS VS RL + AT+ V+++D  D  P F    Y+ ++ E+ +      I  ++A D D G
Sbjct: 225 ASDVSRRLQARATVAVDVLDVQDQPPVFLNAPYSAALPENTAA--GHTILTVRARDGDTG 282

Query: 183 ANSAIRYAIIGGNTQMQFSID-SLSGDVSLVK------TLDYEQVR------SYRLVIRA 229
              ++   +   ++   F +D S  GD ++ K      +LD E  R       Y   ++A
Sbjct: 283 EPRSLLLTLEDEDSG-HFDLDVSREGDATVGKLVTTNVSLDREDPRILQNGGIYTFQVKA 341

Query: 230 QD---GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSI--VRVQAYDA 284
            +      P+ + T+ + I + DV+D  P F    F  ++SE++     +  + +   D 
Sbjct: 342 TELINNEIPAETATSIVTIVVTDVDDLMPVFNQKYFNITISEDIGKDTPLPGLNMIVSDG 401

Query: 285 DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW----VYTSGQ------LDRETQAKYQL 334
           D G NA+ T  + D      +     + P        V    +       D E  A+ QL
Sbjct: 402 DVGENAKYTLALRDDPGYPGISRAFVVGPEEAQGRVPVVVKARNVSVLDYDVEDIARRQL 461

Query: 335 LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394
                        A++               F    Y++ L ED   GT    + A D D
Sbjct: 462 EFEVVALVANQVVASSRVHVRLKDANDHSPEFSQSVYKLSLPEDAGIGTRFGDVFARDYD 521

Query: 395 EDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT 452
             +   L Y + G     +F+   + G   I+V++ LD++ ++ Y LT+ A D GGR   
Sbjct: 522 SGSFGELTYTLRGFGA-DKFATNPKTGG--ISVSKALDYEAQKSYSLTMEAKDGGGRVSA 578

Query: 453 AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI--NAQITYSLSS 510
             + I + D N+  P FE   YT +V E A      + V ATD+D  +  N ++TYS+SS
Sbjct: 579 VNILIELEDVNDNKPAFEQKEYTRTVREGATSFDPQMFVRATDADGPMQGNGKVTYSISS 638

Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLL-DRETMSG-YLLTVTARDGGVPSLSDTTDVE 568
             S       +  F IN  TG +T  K +   +T  G Y L + A D G P L   T + 
Sbjct: 639 HNSMT-----NDVFKINRDTGEVTMAKAVRSDDTERGIYELAIRATDAGTPPLFSETRLS 693

Query: 569 ISVVDVNDNEPVFK---------QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619
           + V    + +P+F+            Y A ++E+A  GT V +V A D D G +  + Y 
Sbjct: 694 VRVGVPGNQKPIFRGNYKSNLPGPSTYRARLLENASPGTEVIRVVANDPD-GRDSLLQYH 752

Query: 620 LDPKDREEGSFVIDPASGVIRT--NKALDRESVA-THDLKAVAIDGGTP-PQSSTVIVHI 675
           +    ++  +FVID +SGVI    +  LD ES    +++   AID GTP  +++T  V +
Sbjct: 753 IASGAKD--NFVIDSSSGVITVSPDARLDLESGGEKYEVIVYAIDSGTPVRETATTTVTV 810

Query: 676 KIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
            + D+N+ PP F       Y+SE + IG  + ++ A DPD   +A + YSI
Sbjct: 811 NMIDVNNKPPTFNESTYLVYVSERAAIGEPVLKVAATDPDS--DAYLEYSI 859



 Score =  199 bits (485), Expect = 1e-48
 Identities = 205/756 (27%), Positives = 328/756 (43%), Gaps = 64/756 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +N++D N+  P F    Y   V E A+ G  VL + ATD D   +A +EY+I  V     
Sbjct: 810  VNMIDVNNKPPTFNESTYLVYVSERAAIGEPVLKVAATDPD--SDAYLEYSI--VEPIRA 865

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
              +             +  FRI+  +G +     LD + VA   +L       + V D+ 
Sbjct: 866  VDKTGVALKNTAPYDYKTAFRINSTTGLITVNRVLDYQ-VAAVVILTVQVQDLNAVVDKE 924

Query: 131  SSTATIHVNII-----DDNDNY--PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183
                 + V I      DDN  +  P +S    T+ +           +  + A +   G 
Sbjct: 925  RQITRVEVTIYIQAYSDDNPTFTNPGWSPNNPTIRISVPEEQPLGTTLLMLSAREPTTG- 983

Query: 184  NSAIRYAIIGGNTQMQF-SIDSLSGDVSLVKTLDYEQVR----SYRLVIRAQDGGSPSRS 238
                R+ ++  +    + ++   SG+V L K LDYE +      +++   A+D     + 
Sbjct: 984  YPVQRFELVREDDDEGYVNVGVQSGNVVLSKRLDYEALNQKFIQFKVRALARDYEITRKM 1043

Query: 239  NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMT 297
            +   +++ ++D NDN P F    ++ SV E+      ++ V+A D D      E+     
Sbjct: 1044 SEANVIVEVQDTNDNNPVFAQKDYKISVLESEKPSKIVLNVKATDMDSSNTEQEVRRGYG 1103

Query: 298  DKDYT--GNVDLPITIDPRSG--WVYTSGQLDRETQAKYQLLVTATD---GGDPPRSATA 350
            +  Y+  G       ++P +G   + T+  LDRE Q+  +  V A+D   GG   RS  A
Sbjct: 1104 EVRYSLIGENANMFEVEPITGNIQIATNTTLDREKQSVLRFYVVASDMPQGGAEQRSTRA 1163

Query: 351  TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITG-GN 407
                           F    Y   + E+ P G  VV +TATD DED    ++YEI   G 
Sbjct: 1164 LVTVDVLDVNDNAPTFEQEAYTAVIPENAPSGVSVVNITATDPDEDKGGVINYEIIDEGE 1223

Query: 408  TRGRFSITSQNGRGLITVAQPLDFK-QERRYVLTVSATDSGG---RSDTAM-VQINITDA 462
              G F I  + G   I  A+ L  K +   Y++ +   D G     SD  + + I    +
Sbjct: 1224 ASGLFEIDHKTGE--IYSARALTGKGRTEPYIMRIRGEDGGEPELYSDVILTLYIGDVVS 1281

Query: 463  NNYAPVF--ENAPYTASVFEDAPIGTTVLVVSATDSDVG--INAQITYSLSSEISNEAVA 518
            N+  P+F        A + E++ IG+ V  V A+D D     N +IT+     + +    
Sbjct: 1282 NDGVPLFIRPTLEEVAYISENSTIGSPVFQVVASDPDDPNLPNGKITFKF---LEDGNFG 1338

Query: 519  HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578
                 F IN +TG ITT KLLDRE    Y L + A+D G P    T  +++ V D++D++
Sbjct: 1339 KDASAFRINSETGLITTRKLLDREAKDSYTLILVAQDLGNPPQQATRVLQVIVNDIDDHK 1398

Query: 579  PVFKQQL----YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634
            P FK+ L        ++E+  +G  V  + A D D+G NG I Y +     E G F+++ 
Sbjct: 1399 PHFKRNLDSPPVELAVLEETPIGAKVGVIEAIDEDIGENGMIDYAI-VYGNEAGLFLVER 1457

Query: 635  A---SGVIRTNKALDRESVATHDLKAVAI------DGGTPPQ------SSTVIVHIKIED 679
                S VIR+N  LDRE  A H L  +         G   P+       S   V +K+ D
Sbjct: 1458 LENNSAVIRSNGRLDRER-ADHHLLTIKCFPYSTKKGDIVPKPYNRQDPSERQVLVKVLD 1516

Query: 680  INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
            I+D+ P F+ + +T  +  N PI T++  + A D D
Sbjct: 1517 IDDNRPKFKKENVTLGVRLNVPIDTSLITLEALDAD 1552



 Score =  140 bits (340), Expect = 4e-31
 Identities = 179/702 (25%), Positives = 306/702 (43%), Gaps = 90/702 (12%)

Query: 250 VNDNAPRFYTS--LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
           V + AP F     + + +VSE  P G  +  ++  D +    ++L Y+++ + +T N D 
Sbjct: 20  VINRAPHFVQGGDMARLAVSEGTPPGAPVYTLKGEDPE---GSKLHYSISGEYFTVNRD- 75

Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATD---GGDPPRSATATXXXXXXXXXXXXX 364
                  SG V     LDRE+Q   +++++ TD    G  P + +               
Sbjct: 76  -------SGVVVLRKALDRESQDLIEVIISITDEGIAGSEPNTVSLRREIAVLDENDNPP 128

Query: 365 XFMPGQYEVELAEDE-------PPGTPVVTLTATDADEDNRLHYEITGGNTRGR----FS 413
            +    Y   + E         PPGT  +T+T  D   +  +H E    +        F+
Sbjct: 129 VYHGRPYAARVPESAHVGGLLVPPGT--ITITDRDGGVNADVHVECVSASRDDDVCDVFN 186

Query: 414 ITSQN-GRGL----ITVAQPLDFKQERRYVLTVSATDSGGRSDT-------AMVQINITD 461
           ++++    G     I++A+ LD+++   Y++ + A D  G SD        A V +++ D
Sbjct: 187 VSTEKLAEGKYDVQISLAKSLDYERRNSYLINLLAID--GASDVSRRLQARATVAVDVLD 244

Query: 462 ANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521
             +  PVF NAPY+A++ E+   G T+L V A D D G    +  +L  E S        
Sbjct: 245 VQDQPPVFLNAPYSAALPENTAAGHTILTVRARDGDTGEPRSLLLTLEDEDSGHFDLDVS 304

Query: 522 QQFVINPQTG-AITTNKLLDRE----TMSGYLLTVTAR-----DGGVPSLSDTTDVEISV 571
           ++   +   G  +TTN  LDRE      +G + T   +     +  +P+ + T+ V I V
Sbjct: 305 REG--DATVGKLVTTNVSLDREDPRILQNGGIYTFQVKATELINNEIPAETATSIVTIVV 362

Query: 572 VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG--ATDADVGLNGRIHYELDPKDREEG- 628
            DV+D  PVF Q+ +   I ED    T +  +    +D DVG N +    L       G 
Sbjct: 363 TDVDDLMPVFNQKYFNITISEDIGKDTPLPGLNMIVSDGDVGENAKYTLALRDDPGYPGI 422

Query: 629 --SFVIDP--ASG----VIRTNKA----LDRESVATHDL--KAVAIDGGTPPQSSTVIVH 674
             +FV+ P  A G    V++         D E +A   L  + VA+       SS   VH
Sbjct: 423 SRAFVVGPEEAQGRVPVVVKARNVSVLDYDVEDIARRQLEFEVVALVANQVVASSR--VH 480

Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734
           ++++D ND  P F        + E++ IGT  G++ A D D G    + Y+++ G  ++ 
Sbjct: 481 VRLKDANDHSPEFSQSVYKLSLPEDAGIGTRFGDVFARDYDSGSFGELTYTLR-GFGADK 539

Query: 735 FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAPV 793
           F+   + G     +     LDYE+ +K Y L + A       + V + I + DVNDN P 
Sbjct: 540 FATNPKTGG----ISVSKALDYEA-QKSYSLTMEAKDGGGRVSAVNILIELEDVNDNKPA 594

Query: 794 MKDFQIIFNNYKDCFPVGPFGRVPAYDAD----VTDKLQYRILSGNNA--NLILLNETTG 847
            +  +      +      P   V A DAD       K+ Y I S N+   ++  +N  TG
Sbjct: 595 FEQKEYTRTVREGATSFDPQMFVRATDADGPMQGNGKVTYSISSHNSMTNDVFKINRDTG 654

Query: 848 SMTLSPQLNTNVPKLATMEVSV--TD-GVNEIKAMMQLSVRL 886
            +T++  + ++  +    E+++  TD G   + +  +LSVR+
Sbjct: 655 EVTMAKAVRSDDTERGIYELAIRATDAGTPPLFSETRLSVRV 696



 Score = 97.1 bits (231), Expect = 6e-18
 Identities = 77/288 (26%), Positives = 138/288 (47%), Gaps = 31/288 (10%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            FRI+  +G + TR  LDRE    YT+++ A D  +P      +T  + V + D +D+ P 
Sbjct: 1344 FRINSETGLITTRKLLDREAKDSYTLILVAQDLGNPPQQ---ATRVLQVIVNDIDDHKPH 1400

Query: 150  FSEKTYTVSVDEDISVTDNPVIAK---IKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206
            F     +  V+  + + + P+ AK   I+A D D+G N  I YAI+ GN    F ++ L 
Sbjct: 1401 FKRNLDSPPVELAV-LEETPIGAKVGVIEAIDEDIGENGMIDYAIVYGNEAGLFLVERLE 1459

Query: 207  GDVSLVKT---LDYEQVRSYRLVIRAQDGGS------PSRSNTT-----QLLINIRDVND 252
             + +++++   LD E+   + L I+     +      P   N       Q+L+ + D++D
Sbjct: 1460 NNSAVIRSNGRLDRERADHHLLTIKCFPYSTKKGDIVPKPYNRQDPSERQVLVKVLDIDD 1519

Query: 253  NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD------ 306
            N P+F        V  NVPI  S++ ++A DAD      + Y+M    +T  VD      
Sbjct: 1520 NRPKFKKENVTLGVRLNVPIDTSLITLEALDADSDA-LPINYSMGKASFTSLVDPSMSRR 1578

Query: 307  -LP--ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
             +P  ++++ ++G + T+G +        +++V+A +   P R    T
Sbjct: 1579 KIPSHLSLNSQTGELRTTGSMSSYADGYMEIIVSANNSVTPARETNIT 1626


>UniRef50_Q4SVM8 Cluster: Chromosome 1 SCAF13750, whole genome shotgun
            sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1
            SCAF13750, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 2845

 Score =  229 bits (560), Expect = 8e-58
 Identities = 170/580 (29%), Positives = 278/580 (47%), Gaps = 25/580 (4%)

Query: 180  DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ-DGGSPSRS 238
            DVG  +     ++ G  Q  F ++   G +S+ + +D E++ +      A       +  
Sbjct: 1820 DVGRLTDRNLRLLSGTKQDLFKVNPSDGVLSVKRRVDREELCAKMAPCVANLKAVVENPL 1879

Query: 239  NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
               Q++I I DVNDNAP+F    +   V E+  +G       A+D + G+N+  TY + +
Sbjct: 1880 EMHQVIIEILDVNDNAPKFPEENYTLEVLESAMVGSRFQIEGAHDLEVGINSLQTYKINN 1939

Query: 299  KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358
              Y          D +  ++    QLDRE  A++ L VTA DGG P +S           
Sbjct: 1940 NQYFRVETEEFGEDGKVPFLILHRQLDREQTAQHWLKVTALDGGKPIKSGNLNITVIVSD 1999

Query: 359  XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITG---GNTRGRFS 413
                       +Y V + E+ P GT ++T+ A+D DE  ++ + Y +     G     F+
Sbjct: 2000 INDNPPVCDKQKYVVTVKENAPEGTFLLTVNASDPDEGMNSAIEYSLRSKLRGIHSDPFN 2059

Query: 414  ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFEN 471
            + S  G+  +TV   LD+++++ Y + V A D G    S    V + + D N+  P  E 
Sbjct: 2060 LDSTTGK--LTVKAGLDYEEKQVYEIKVLAADKGSVSLSTHCNVVVRVEDVNDNPPEIEI 2117

Query: 472  APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
               ++S+ EDAP GT V ++  TD D G+N Q+  S+ + +  +     D        + 
Sbjct: 2118 TSLSSSIPEDAPPGTVVALMGVTDRDSGVNGQVICSVPAHLPFDLKPSPDGH------SY 2171

Query: 532  AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
            ++ T   LD+E+   Y + +TA+D G P+LS T  + + V+DVNDN P+F +  YT  + 
Sbjct: 2172 SLVTKDYLDKESTHMYDIQITAKDLGSPALSSTKVIHVDVLDVNDNRPLFSESPYTFYVP 2231

Query: 592  EDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFV-IDPASGVIRTNKALDRES 649
            E+   G+SV  V A+D D G N  + Y L   +D    SF+ I+ A+G I   K  D E+
Sbjct: 2232 ENNKAGSSVFTVSASDVDSGQNAALSYSLIRNQDLTITSFLNINEANGTISALKTFDFET 2291

Query: 650  VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF----ESDCLTFYISE---NSPI 702
            + T   + VA D G+P  SS V V + I D ND+ PV      S+     + E   N   
Sbjct: 2292 LKTFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNA 2351

Query: 703  GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
            G  + ++RA+D D G N  + ++++   D + F L+   G
Sbjct: 2352 GHLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTG 2391



 Score =  223 bits (544), Expect = 7e-56
 Identities = 178/607 (29%), Positives = 270/607 (44%), Gaps = 28/607 (4%)

Query: 87   QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146
            QD+F+++   G L  +  +DRE++        A  +A  V + L     I + I+D NDN
Sbjct: 1837 QDLFKVNPSDGVLSVKRRVDREELCAKMAPCVANLKAV-VENPLEMHQVI-IEILDVNDN 1894

Query: 147  YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206
             P+F E+ YT+ V E   V     I    A D +VG NS   Y I   N   +   +   
Sbjct: 1895 APKFPEENYTLEVLESAMVGSRFQIEG--AHDLEVGINSLQTYKI-NNNQYFRVETEEFG 1951

Query: 207  GD-----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261
             D     + L + LD EQ   + L + A DGG P +S    + + + D+NDN P      
Sbjct: 1952 EDGKVPFLILHRQLDREQTAQHWLKVTALDGGKPIKSGNLNITVIVSDINDNPPVCDKQK 2011

Query: 262  FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321
            +  +V EN P G  ++ V A D DEG+N+ + Y++  K   G    P  +D  +G +   
Sbjct: 2012 YVVTVKENAPEGTFLLTVNASDPDEGMNSAIEYSLRSK-LRGIHSDPFNLDSTTGKLTVK 2070

Query: 322  GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381
              LD E +  Y++ V A D G    S                           + ED PP
Sbjct: 2071 AGLDYEEKQVYEIKVLAADKGSVSLSTHCNVVVRVEDVNDNPPEIEITSLSSSIPEDAPP 2130

Query: 382  GTPVVTLTATDADEDNRLHYEITGGNTRGRFSI-TSQNGRGLITVAQP-LDFKQERRYVL 439
            GT V  +  TD D        I        F +  S +G     V +  LD +    Y +
Sbjct: 2131 GTVVALMGVTDRDSGVN-GQVICSVPAHLPFDLKPSPDGHSYSLVTKDYLDKESTHMYDI 2189

Query: 440  TVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497
             ++A D G    S T ++ +++ D N+  P+F  +PYT  V E+   G++V  VSA+D D
Sbjct: 2190 QITAKDLGSPALSSTKVIHVDVLDVNDNRPLFSESPYTFYVPENNKAGSSVFTVSASDVD 2249

Query: 498  VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG 557
             G NA ++YSL   I N+ +        IN   G I+  K  D ET+  +   V A D G
Sbjct: 2250 SGQNAALSYSL---IRNQDLT-ITSFLNINEANGTISALKTFDFETLKTFQFQVVASDSG 2305

Query: 558  VPSLSDTTDVEISVVDVNDNEPVFKQQLYT-------ANIMEDALVGTSVSQVGATDADV 610
             PSLS    V++ ++D NDN PV    + +         I  +   G  V++V A DAD+
Sbjct: 2306 SPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDADI 2365

Query: 611  GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST 670
            G NG + + L  +  +   F +D  +G IRT ++      A H L  +  D G    S+T
Sbjct: 2366 GYNGWLLFALQ-EVSDHSLFGLDRYTGQIRTLRSFTETDEAEHKLVILVKDNGNVSLSAT 2424

Query: 671  VIVHIKI 677
              V +K+
Sbjct: 2425 ATVLVKL 2431



 Score =  199 bits (486), Expect = 8e-49
 Identities = 160/558 (28%), Positives = 254/558 (45%), Gaps = 30/558 (5%)

Query: 136  IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195
            I V I D NDN P F   T  + + E  SV +    +   A D DVG+NS   Y +   +
Sbjct: 1119 IEVEITDINDNAPHFRRGTMHLDISESSSVGER--FSLNNAADPDVGSNSVKDYHL---S 1173

Query: 196  TQMQFSIDSLSG-------DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
                FSI+  +G       D+ L K LD E    + L++ A DGG P+R+ T  +++ + 
Sbjct: 1174 ASEHFSINIQTGRDGTKFADLILTKALDREMQAVHNLILTAVDGGVPTRTGTASIVVRVL 1233

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NVDL 307
            DVNDNAP F    +   V EN PIG  ++++ A D DEG N+++ Y+ +   YT      
Sbjct: 1234 DVNDNAPSFDREKYVVDVMENSPIGSLVLKLNATDLDEGSNSDIVYSYS--LYTSERTQQ 1291

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
               ++P +G +     ++ E    +++ V A+D G    S                    
Sbjct: 1292 VFHLNPENGEIRVREMINYEDLKLFEMEVIASDKGPNLLSGQCKLTIQVTDMNDNHPEIS 1351

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
               ++  + E+    T +  ++ +D D  DN +           +   +S N   L+ V+
Sbjct: 1352 IKSFQSPVKENIDVETVIAVVSVSDKDSGDNGVVDLHIPDKMPFKLRQSSDNYYELV-VS 1410

Query: 427  QPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
            +PLD ++   Y +T + TD G    SD   + + + D N+  P F  + YT  V E+   
Sbjct: 1411 EPLDREKVPEYDITFTVTDRGSPPLSDNETMTLELLDVNDNVPRFPQSFYTIRVTENNAP 1470

Query: 485  GTTVLVVSATDSDVGINAQITY-SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
            G  +  ++A D D+  N  + Y  L  EI+N +++     F INP+ G +   K  D E 
Sbjct: 1471 GALLSSLTAFDPDLHENQYLVYFILEKEIANTSMS---MLFSINPENGNLYALKTFDYEI 1527

Query: 544  MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT-ANIMEDAL-----VG 597
               +L  + ARD G P LS    V I +VD NDN PV         +++E+ +      G
Sbjct: 1528 EKEFLFHIEARDSGSPPLSSNVTVHIVIVDQNDNAPVIVSPWRAQGSVVEEKIPRSTDKG 1587

Query: 598  TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
            + V++V A D D   N RI Y+L  +  +   F +D  +G IRT +           L  
Sbjct: 1588 SLVAKVIALDVDSVHNSRITYQL-LQVTDATLFSLDQYNGEIRTMRMFSYRDPRHQRLVV 1646

Query: 658  VAIDGGTPPQSSTVIVHI 675
            VA D G P  S+TV + +
Sbjct: 1647 VAKDNGDPALSATVTIKL 1664



 Score =  196 bits (477), Expect = 1e-47
 Identities = 125/376 (33%), Positives = 198/376 (52%), Gaps = 21/376 (5%)

Query: 429  LDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
            LD +Q  ++ L V+A D G   +S    + + ++D N+  PV +   Y  +V E+AP GT
Sbjct: 1965 LDREQTAQHWLKVTALDGGKPIKSGNLNITVIVSDINDNPPVCDKQKYVVTVKENAPEGT 2024

Query: 487  TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
             +L V+A+D D G+N+ I YSL S++       H   F ++  TG +T    LD E    
Sbjct: 2025 FLLTVNASDPDEGMNSAIEYSLRSKLRGI----HSDPFNLDSTTGKLTVKAGLDYEEKQV 2080

Query: 547  YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
            Y + V A D G  SLS   +V + V DVNDN P  +    +++I EDA  GT V+ +G T
Sbjct: 2081 YEIKVLAADKGSVSLSTHCNVVVRVEDVNDNPPEIEITSLSSSIPEDAPPGTVVALMGVT 2140

Query: 607  DADVGLNGRI------HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
            D D G+NG++      H   D K   +G       S  + T   LD+ES   +D++  A 
Sbjct: 2141 DRDSGVNGQVICSVPAHLPFDLKPSPDGH------SYSLVTKDYLDKESTHMYDIQITAK 2194

Query: 661  DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
            D G+P  SST ++H+ + D+ND+ P+F     TFY+ EN+  G+++  + A D D G NA
Sbjct: 2195 DLGSPALSSTKVIHVDVLDVNDNRPLFSESPYTFYVPENNKAGSSVFTVSASDVDSGQNA 2254

Query: 721  VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIR-AASPPLWNDV 778
             + YS+    D    S           +  +   D+E+ +  ++++V   + SP L ++V
Sbjct: 2255 ALSYSLIRNQDLTITSF-LNINEANGTISALKTFDFETLKTFQFQVVASDSGSPSLSSNV 2313

Query: 779  RVEILVTDVNDNAPVM 794
             V++ + D NDNAPV+
Sbjct: 2314 TVKVFILDQNDNAPVI 2329



 Score =  190 bits (463), Expect = 5e-46
 Identities = 163/586 (27%), Positives = 259/586 (44%), Gaps = 59/586 (10%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ + D ND++P F        + E +S G       A D D+G N+  +Y +      +
Sbjct: 1120 EVEITDINDNAPHFRRGTMHLDISESSSVGERFSLNNAADPDVGSNSVKDYHLSASEHFS 1179

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            +N +                      +  +LT+A LDRE  A + +++ A D   P    
Sbjct: 1180 INIQTGRDGTKF--------------ADLILTKA-LDREMQAVHNLILTAVDGGVPTR-- 1222

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             + TA+I V ++D NDN P F  + Y V V E+  +    ++ K+ ATD D G+NS I Y
Sbjct: 1223 -TGTASIVVRVLDVNDNAPSFDREKYVVDVMENSPI--GSLVLKLNATDLDEGSNSDIVY 1279

Query: 190  A---IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            +        TQ  F ++  +G++ + + ++YE ++ + + + A D G    S   +L I 
Sbjct: 1280 SYSLYTSERTQQVFHLNPENGEIRVREMINYEDLKLFEMEVIASDKGPNLLSGQCKLTIQ 1339

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            + D+NDN P      FQ  V EN+ +   I  V   D D G N  +   + DK       
Sbjct: 1340 VTDMNDNHPEISIKSFQSPVKENIDVETVIAVVSVSDKDSGDNGVVDLHIPDK------- 1392

Query: 307  LPITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
            +P  +   S   Y    S  LDRE   +Y +  T TD G PP S   T            
Sbjct: 1393 MPFKLRQSSDNYYELVVSEPLDREKVPEYDITFTVTDRGSPPLSDNETMTLELLDVNDNV 1452

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHY-----EITGGNTRGRFSITS 416
              F    Y + + E+  PG  + +LTA D D  E+  L Y     EI   +    FSI  
Sbjct: 1453 PRFPQSFYTIRVTENNAPGALLSSLTAFDPDLHENQYLVYFILEKEIANTSMSMLFSINP 1512

Query: 417  QNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPY 474
            +NG   +   +  D++ E+ ++  + A DSG    S    V I I D N+ APV   +P+
Sbjct: 1513 ENGN--LYALKTFDYEIEKEFLFHIEARDSGSPPLSSNVTVHIVIVDQNDNAPVIV-SPW 1569

Query: 475  TA--SVFED-----APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527
             A  SV E+        G+ V  V A D D   N++ITY L  ++++  +      F ++
Sbjct: 1570 RAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQL-LQVTDATL------FSLD 1622

Query: 528  PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
               G I T ++          L V A+D G P+LS T  +++S V+
Sbjct: 1623 QYNGEIRTMRMFSYRDPRHQRLVVVAKDNGDPALSATVTIKLSTVE 1668



 Score =  189 bits (461), Expect = 8e-46
 Identities = 161/586 (27%), Positives = 263/586 (44%), Gaps = 46/586 (7%)

Query: 4    PFCIHQQI-NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
            P  +HQ I  +LD ND++P F  + Y   V E A  G+      A D ++G N+   Y I
Sbjct: 1878 PLEMHQVIIEILDVNDNAPKFPEENYTLEVLESAMVGSRFQIEGAHDLEVGINSLQTYKI 1937

Query: 63   ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122
                   +  E+               F  DG+   L+    LDRE+ A++ + V A D 
Sbjct: 1938 NNNQYFRVETEE---------------FGEDGKVPFLILHRQLDREQTAQHWLKVTALDG 1982

Query: 123  ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
              P+    S    I V + D NDN P   ++ Y V+V E+    +   +  + A+D D G
Sbjct: 1983 GKPIK---SGNLNITVIVSDINDNPPVCDKQKYVVTVKEN--APEGTFLLTVNASDPDEG 2037

Query: 183  ANSAIRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239
             NSAI Y++   + G     F++DS +G +++   LDYE+ + Y + + A D GS S S 
Sbjct: 2038 MNSAIEYSLRSKLRGIHSDPFNLDSTTGKLTVKAGLDYEEKQVYEIKVLAADKGSVSLST 2097

Query: 240  TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
               +++ + DVNDN P    +    S+ E+ P G  +  +   D D GVN ++  ++   
Sbjct: 2098 HCNVVVRVEDVNDNPPEIEITSLSSSIPEDAPPGTVVALMGVTDRDSGVNGQVICSVPAH 2157

Query: 300  DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
                  DL  + D  S  + T   LD+E+   Y + +TA D G P  S+T          
Sbjct: 2158 ---LPFDLKPSPDGHSYSLVTKDYLDKESTHMYDIQITAKDLGSPALSSTKVIHVDVLDV 2214

Query: 360  XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQ 417
                  F    Y   + E+   G+ V T++A+D D  ++  L Y +         S  + 
Sbjct: 2215 NDNRPLFSESPYTFYVPENNKAGSSVFTVSASDVDSGQNAALSYSLIRNQDLTITSFLNI 2274

Query: 418  N-GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVF---EN 471
            N   G I+  +  DF+  + +   V A+DSG    S    V++ I D N+ APV     +
Sbjct: 2275 NEANGTISALKTFDFETLKTFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVS 2334

Query: 472  APYTASVFEDAP----IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527
            +  +A   E+ P     G  V  V A D+D+G N  + ++L  E+S+ ++      F ++
Sbjct: 2335 SNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFAL-QEVSDHSL------FGLD 2387

Query: 528  PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
              TG I T +       + + L +  +D G  SLS T  V + +V+
Sbjct: 2388 RYTGQIRTLRSFTETDEAEHKLVILVKDNGNVSLSATATVLVKLVE 2433



 Score =  182 bits (442), Expect = 2e-43
 Identities = 148/578 (25%), Positives = 258/578 (44%), Gaps = 29/578 (5%)

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGR--- 420
            F  G   ++++E    G       A D D   ++   Y ++       FSI  Q GR   
Sbjct: 1133 FRRGTMHLDISESSSVGERFSLNNAADPDVGSNSVKDYHLSASE---HFSINIQTGRDGT 1189

Query: 421  --GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTA 476
                + + + LD + +  + L ++A D G   R+ TA + + + D N+ AP F+   Y  
Sbjct: 1190 KFADLILTKALDREMQAVHNLILTAVDGGVPTRTGTASIVVRVLDVNDNAPSFDREKYVV 1249

Query: 477  SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
             V E++PIG+ VL ++ATD D G N+ I YS S   S        Q F +NP+ G I   
Sbjct: 1250 DVMENSPIGSLVLKLNATDLDEGSNSDIVYSYSLYTSERT----QQVFHLNPENGEIRVR 1305

Query: 537  KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
            ++++ E +  + + V A D G   LS    + I V D+NDN P    + + + + E+  V
Sbjct: 1306 EMINYEDLKLFEMEVIASDKGPNLLSGQCKLTIQVTDMNDNHPEISIKSFQSPVKENIDV 1365

Query: 597  GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
             T ++ V  +D D G NG +   +  K   +     D    ++  ++ LDRE V  +D+ 
Sbjct: 1366 ETVIAVVSVSDKDSGDNGVVDLHIPDKMPFKLRQSSDNYYELV-VSEPLDREKVPEYDIT 1424

Query: 657  AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
                D G+PP S    + +++ D+ND+ P F     T  ++EN+  G  +  + A DPD 
Sbjct: 1425 FTVTDRGSPPLSDNETMTLELLDVNDNVPRFPQSFYTIRVTENNAPGALLSSLTAFDPDL 1484

Query: 717  GPNAVVHYSIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIR-AASPP 773
              N  + Y I   + +N S S+      +   L  +   DYE  ++  + +  R + SPP
Sbjct: 1485 HENQYLVYFILEKEIANTSMSMLFSINPENGNLYALKTFDYEIEKEFLFHIEARDSGSPP 1544

Query: 774  LWNDVRVEILVTDVNDNAPVM-----KDFQIIFNNYKDCFPVGPF-GRVPAYDADV--TD 825
            L ++V V I++ D NDNAPV+         ++          G    +V A D D     
Sbjct: 1545 LSSNVTVHIVIVDQNDNAPVIVSPWRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNS 1604

Query: 826  KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVR 885
            ++ Y++L   +A L  L++  G +      +   P+   + V   D   +      ++++
Sbjct: 1605 RITYQLLQVTDATLFSLDQYNGEIRTMRMFSYRDPRHQRLVVVAKDN-GDPALSATVTIK 1663

Query: 886  LITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAI 923
            L T E  + + +            S L  + + GL ++
Sbjct: 1664 LSTVETAVKAYSDMTEVPLEYDIFSDLNLYLVIGLGSV 1701



 Score =  173 bits (422), Expect = 4e-41
 Identities = 127/427 (29%), Positives = 198/427 (46%), Gaps = 17/427 (3%)

Query: 455  VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
            V I I D N+ AP F    YT  V E A +G+   +  A D +VGIN+  TY +++   N
Sbjct: 1884 VIIEILDVNDNAPKFPEENYTLEVLESAMVGSRFQIEGAHDLEVGINSLQTYKINN---N 1940

Query: 515  EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
            +      ++F  + +   +  ++ LDRE  + + L VTA DGG P  S   ++ + V D+
Sbjct: 1941 QYFRVETEEFGEDGKVPFLILHRQLDREQTAQHWLKVTALDGGKPIKSGNLNITVIVSDI 2000

Query: 575  NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR--EEGSFVI 632
            NDN PV  +Q Y   + E+A  GT +  V A+D D G+N  I Y L  K R      F +
Sbjct: 2001 NDNPPVCDKQKYVVTVKENAPEGTFLLTVNASDPDEGMNSAIEYSLRSKLRGIHSDPFNL 2060

Query: 633  DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692
            D  +G +     LD E    +++K +A D G+   S+   V +++ED+ND+PP  E   L
Sbjct: 2061 DSTTGKLTVKAGLDYEEKQVYEIKVLAADKGSVSLSTHCNVVVRVEDVNDNPPEIEITSL 2120

Query: 693  TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752
            +  I E++P GT +  +   D D G N  V  S+        F L+         LVT  
Sbjct: 2121 SSSIPEDAPPGTVVALMGVTDRDSGVNGQVICSVPA---HLPFDLKPSPDGHSYSLVTKD 2177

Query: 753  DLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809
             LD ES    Y++ I A    SP L +   + + V DVNDN P+  +    F   ++   
Sbjct: 2178 YLDKESTH-MYDIQITAKDLGSPALSSTKVIHVDVLDVNDNRPLFSESPYTFYVPENNKA 2236

Query: 810  VGPFGRVPAYDADVTDK--LQYRILSGNN---ANLILLNETTGSMTLSPQLNTNVPKLAT 864
                  V A D D      L Y ++   +    + + +NE  G+++     +    K   
Sbjct: 2237 GSSVFTVSASDVDSGQNAALSYSLIRNQDLTITSFLNINEANGTISALKTFDFETLKTFQ 2296

Query: 865  MEVSVTD 871
             +V  +D
Sbjct: 2297 FQVVASD 2303



 Score =  163 bits (396), Expect = 6e-38
 Identities = 178/710 (25%), Positives = 295/710 (41%), Gaps = 83/710 (11%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ + D ND++P F        + E +S G       A D D+G N+  +Y +      +
Sbjct: 321 EVEITDINDNAPHFRRGTMHLDISESSSVGERFSLNNAADPDVGSNSVKDYHLSASEHFS 380

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
           +N +                      +  +LT+A LDRE  A + +++ A D   P    
Sbjct: 381 INIQTGRDGTKF--------------ADLILTKA-LDREMQAVHNLILTAVDGGVP---- 421

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
              T T      D NDN+P+ S K++   V E+I V    VIA +  +D D G N  +  
Sbjct: 422 ---TRT------DMNDNHPEISIKSFQSPVKENIDV--ETVIAVVSVSDKDSGDNGVVDL 470

Query: 190 AIIGGNTQMQFSIDSLSG---DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            I     +M F +   S    ++ + + LD E+V  Y +     D GSP  S+   + + 
Sbjct: 471 HI---PDKMPFKLRQSSDNYYELVVSEPLDREKVPEYDITFTVTDRGSPPLSDNETMTLE 527

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NV 305
           + DVNDN PRF  S +   V+EN   G  +  + A+D D   N  L Y + +K+    ++
Sbjct: 528 LLDVNDNVPRFPQSFYTIRVTENNAPGALLSSLTAFDPDLHENQYLVYFILEKEIANTSM 587

Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
            +  +I+P +G +Y     D E + ++   + A D G PP S+  T              
Sbjct: 588 SMLFSINPENGNLYALKTFDYEIEKEFLFHIEARDSGSPPLSSNVTVHIVIVDQNDNAPV 647

Query: 366 FM-PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLIT 424
            + P + +      E P   V+ L   D+  ++R+ Y++        FS+   NG   I 
Sbjct: 648 IVSPWRAQGLCGGGEDP--QVIALD-VDSVHNSRITYKLLQVTDATLFSLDQYNGE--IR 702

Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN---APYTASVFED 481
             +   ++  R   L V A D+G  + +A V I ++        + +    P    +F D
Sbjct: 703 TMRMFSYRDPRHQRLVVVAKDNGDPALSATVTIKLSTVETAVKAYSDMTEVPLEYDIFSD 762

Query: 482 ----APIGTTVLVVSATDS----DVGINAQITYSLSSEISNEAVAH-------------- 519
                 IG  + V+SA  S     V      T + S+ +SN+A  +              
Sbjct: 763 LNLYLVIGAGLGVLSAAHSPSWNSVISERNSTIADSTLVSNDAYWYSLFLAETRKGKLVV 822

Query: 520 -----HDQQFVINP---QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571
                   +++++    + G +   K  D E    +L  + ARD G P LS    V I +
Sbjct: 823 RQPVPKGSRYIVSSIPRENGNLYALKTFDYEIEKEFLFHIEARDSGSPPLSSNVTVHIVI 882

Query: 572 VDVNDNEPVFKQQLYT-ANIMEDAL-----VGTSVSQVGATDADVGLNGRIHYELDPKDR 625
           VD NDN PV         +++E+ +      G+ V++V A D D   N RI Y+L  +  
Sbjct: 883 VDQNDNAPVIVSPWRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQL-LQVT 941

Query: 626 EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675
           +   F +D  +G IRT +           L  VA D G P  S+TV + +
Sbjct: 942 DATLFSLDQYNGEIRTMRMFSYRDPRHQRLVVVAKDNGDPALSATVTIKL 991



 Score =  153 bits (370), Expect = 9e-35
 Identities = 235/982 (23%), Positives = 387/982 (39%), Gaps = 104/982 (10%)

Query: 11   INVLDCNDHSPVF------EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIEL 64
            I ++D ND++PV       +    E  +      G+ V  + A D D   N+ + Y +  
Sbjct: 82   IVIVDQNDNAPVIVSPWRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQLLQ 141

Query: 65   VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS 124
            VT  TL   D               +R D R   L+  A  + +     TV +K +   +
Sbjct: 142  VTDATLFSLDQYNGEIRTMRMFS--YR-DPRHQRLVVVAKDNGDPALSATVTIKLSTVET 198

Query: 125  PVSDRLSSTAT-IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183
             V      T   +  +I  D + Y      + +  +   I VT   ++ K +   A   A
Sbjct: 199  AVKAYSDMTEVPLEYDIFSDLNLYLVIGLGSVSFLLLITILVT---IVIKCQKPKASKAA 255

Query: 184  NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT-- 241
              A R ++I            +S D     +L   + R  +LV+R Q     SR + T  
Sbjct: 256  -PACRNSVISERNSTIADSTLVSNDAYWY-SLFLAETRKGKLVVR-QPVPKGSRLDATIE 312

Query: 242  ------QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295
                   + + I D+NDNAP F        +SE+  +G       A D D G N+   Y 
Sbjct: 313  NPVRMFNIEVEITDINDNAPHFRRGTMHLDISESSSVGERFSLNNAADPDVGSNSVKDYH 372

Query: 296  MTDKDYTG-NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354
            ++  ++   N+         +  + T   LDRE QA + L++TA DGG P R+       
Sbjct: 373  LSASEHFSINIQTGRDGTKFADLILTKA-LDREMQAVHNLILTAVDGGVPTRTDMNDNHP 431

Query: 355  XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFS 413
                            ++  + E+    T +  ++ +D D  DN +           +  
Sbjct: 432  EISIKS----------FQSPVKENIDVETVIAVVSVSDKDSGDNGVVDLHIPDKMPFKLR 481

Query: 414  ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFEN 471
             +S N   L+ V++PLD ++   Y +T + TD G    SD   + + + D N+  P F  
Sbjct: 482  QSSDNYYELV-VSEPLDREKVPEYDITFTVTDRGSPPLSDNETMTLELLDVNDNVPRFPQ 540

Query: 472  APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS-LSSEISNEAVAHHDQQFVINPQT 530
            + YT  V E+   G  +  ++A D D+  N  + Y  L  EI+N +++     F INP+ 
Sbjct: 541  SFYTIRVTENNAPGALLSSLTAFDPDLHENQYLVYFILEKEIANTSMS---MLFSINPEN 597

Query: 531  GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590
            G +   K  D E    +L  + ARD G P LS    V I +VD NDN PV         +
Sbjct: 598  GNLYALKTFDYEIEKEFLFHIEARDSGSPPLSSNVTVHIVIVDQNDNAPVIVSPWRAQGL 657

Query: 591  MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650
                  G    QV A D D   N RI Y+L  +  +   F +D  +G IRT +       
Sbjct: 658  CG----GGEDPQVIALDVDSVHNSRITYKL-LQVTDATLFSLDQYNGEIRTMRMFSYRDP 712

Query: 651  ATHDLKAVAIDGGTPPQSSTVIVHIKI--------EDINDSPPVFE--SDCLTFYISENS 700
                L  VA D G P  S+TV + +           D+ + P  ++  SD L  Y+    
Sbjct: 713  RHQRLVVVAKDNGDPALSATVTIKLSTVETAVKAYSDMTEVPLEYDIFSD-LNLYLV--- 768

Query: 701  PIGTTIGEIRA-HDPDEGP-----NAVVHYSIKGGDDSNSFSL---ETRQGS-------- 743
             IG  +G + A H P         N+ +  S    +D+  +SL   ETR+G         
Sbjct: 769  -IGAGLGVLSAAHSPSWNSVISERNSTIADSTLVSNDAYWYSLFLAETRKGKLVVRQPVP 827

Query: 744  ------------DKAELVTMVDLDYESPRK-KYELVIR-AASPPLWNDVRVEILVTDVND 789
                        +   L  +   DYE  ++  + +  R + SPPL ++V V I++ D ND
Sbjct: 828  KGSRYIVSSIPRENGNLYALKTFDYEIEKEFLFHIEARDSGSPPLSSNVTVHIVIVDQND 887

Query: 790  NAPVM-----KDFQIIFNNYKDCFPVGPF-GRVPAYDADV--TDKLQYRILSGNNANLIL 841
            NAPV+         ++          G    +V A D D     ++ Y++L   +A L  
Sbjct: 888  NAPVIVSPWRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQLLQVTDATLFS 947

Query: 842  LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLN 901
            L++  G +      +   P+   + V   D   +      ++++L T E  + + +    
Sbjct: 948  LDQYNGEIRTMRMFSYRDPRHQRLVVVAKDN-GDPALSATVTIKLSTVETAVKAYSDMTE 1006

Query: 902  DMTAEQFLSPLLGFFIDGLAAI 923
                    S L  + + GL ++
Sbjct: 1007 VPLEYDIFSDLNLYLVIGLGSV 1028



 Score =  151 bits (366), Expect = 3e-34
 Identities = 93/279 (33%), Positives = 144/279 (51%), Gaps = 15/279 (5%)

Query: 524  FVINPQTGAITTNKLLDRETMSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVNDNEPVFK 582
            F +NP  G ++  + +DRE +   +    A     V +  +   V I ++DVNDN P F 
Sbjct: 1840 FKVNPSDGVLSVKRRVDREELCAKMAPCVANLKAVVENPLEMHQVIIEILDVNDNAPKFP 1899

Query: 583  QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR---EEGSFVIDPASGVI 639
            ++ YT  ++E A+VG+     GA D +VG+N    Y+++       E   F  D     +
Sbjct: 1900 EENYTLEVLESAMVGSRFQIEGAHDLEVGINSLQTYKINNNQYFRVETEEFGEDGKVPFL 1959

Query: 640  RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699
              ++ LDRE  A H LK  A+DGG P +S  + + + + DIND+PPV +       + EN
Sbjct: 1960 ILHRQLDREQTAQHWLKVTALDGGKPIKSGNLNITVIVSDINDNPPVCDKQKYVVTVKEN 2019

Query: 700  SPIGTTIGEIRAHDPDEGPNAVVHYSIKG---GDDSNSFSLETRQGSDKAELVTMVDLDY 756
            +P GT +  + A DPDEG N+ + YS++    G  S+ F+L++  G    +L     LDY
Sbjct: 2020 APEGTFLLTVNASDPDEGMNSAIEYSLRSKLRGIHSDPFNLDSTTG----KLTVKAGLDY 2075

Query: 757  ESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAP 792
            E  ++ YE+ + AA   S  L     V + V DVNDN P
Sbjct: 2076 EE-KQVYEIKVLAADKGSVSLSTHCNVVVRVEDVNDNPP 2113



 Score =  131 bits (317), Expect = 2e-28
 Identities = 137/534 (25%), Positives = 228/534 (42%), Gaps = 58/534 (10%)

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM-P 368
            +I   +G +Y     D E + ++   + A D G PP S+  T               + P
Sbjct: 836  SIPRENGNLYALKTFDYEIEKEFLFHIEARDSGSPPLSSNVTVHIVIVDQNDNAPVIVSP 895

Query: 369  GQYEVELAEDEPP-----GTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRG 421
             + +  + E++ P     G+ V  + A D D   ++R+ Y++        FS+   NG  
Sbjct: 896  WRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQLLQVTDATLFSLDQYNGE- 954

Query: 422  LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN---APYTASV 478
             I   +   ++  R   L V A D+G  + +A V I ++        + +    P    +
Sbjct: 955  -IRTMRMFSYRDPRHQRLVVVAKDNGDPALSATVTIKLSTVETAVKAYSDMTEVPLEYDI 1013

Query: 479  FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA-VAHHDQQFVINPQTGAITTNK 537
            F D  +   V+ + +    + I   +T  +  +    +  A   +  VI+ +   I  + 
Sbjct: 1014 FSDLNL-YLVIGLGSVSFLLLITILVTIVIKCQKPKASKAAPACRNSVISERNSTIADST 1072

Query: 538  LLDR----------ETMSGYLLTVTARDGGVPSLSDTTD-------VEISVVDVNDNEPV 580
            L+            ET  G L+       G P L  T +       +E+ + D+NDN P 
Sbjct: 1073 LVSNDAYWYSLFLAETRKGKLVVRQPVPKGSPRLDATIENPVRMFNIEVEITDINDNAPH 1132

Query: 581  FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640
            F++     +I E + VG   S   A D DVG N    Y L   +     F I+  +G   
Sbjct: 1133 FRRGTMHLDISESSSVGERFSLNNAADPDVGSNSVKDYHLSASEH----FSINIQTGRDG 1188

Query: 641  TN-------KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693
            T        KALDRE  A H+L   A+DGG P ++ T  + +++ D+ND+ P F+ +   
Sbjct: 1189 TKFADLILTKALDREMQAVHNLILTAVDGGVPTRTGTASIVVRVLDVNDNAPSFDREKYV 1248

Query: 694  FYISENSPIGTTIGEIRAHDPDEGPNA--VVHYSIKGGDDSNS-FSLETRQGSDKA-ELV 749
              + ENSPIG+ + ++ A D DEG N+  V  YS+   + +   F L    G  +  E++
Sbjct: 1249 VDVMENSPIGSLVLKLNATDLDEGSNSDIVYSYSLYTSERTQQVFHLNPENGEIRVREMI 1308

Query: 750  TMVDLDYESPRKKYEL-VIRAASPP--LWNDVRVEILVTDVNDNAP--VMKDFQ 798
               DL      K +E+ VI +   P  L    ++ I VTD+NDN P   +K FQ
Sbjct: 1309 NYEDL------KLFEMEVIASDKGPNLLSGQCKLTIQVTDMNDNHPEISIKSFQ 1356



 Score =  111 bits (268), Expect = 2e-22
 Identities = 142/565 (25%), Positives = 224/565 (39%), Gaps = 64/565 (11%)

Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM-PGQYEV 373
           +G +Y     D E + ++   + A D G PP S+  T               + P + + 
Sbjct: 43  NGNLYALKTFDYEIEKEFLFHIEARDSGSPPLSSNVTVHIVIVDQNDNAPVIVSPWRAQG 102

Query: 374 ELAEDEPP-----GTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
            + E++ P     G+ V  + A D D   ++R+ Y++        FS+   NG   I   
Sbjct: 103 SVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQLLQVTDATLFSLDQYNGE--IRTM 160

Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN---APYTASVFEDAP 483
           +   ++  R   L V A D+G  + +A V I ++        + +    P    +F D  
Sbjct: 161 RMFSYRDPRHQRLVVVAKDNGDPALSATVTIKLSTVETAVKAYSDMTEVPLEYDIFSDLN 220

Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEA-VAHHDQQFVINPQTGAITTNKLLDRE 542
           +   V+ + +    + I   +T  +  +    +  A   +  VI+ +   I  + L+  +
Sbjct: 221 L-YLVIGLGSVSFLLLITILVTIVIKCQKPKASKAAPACRNSVISERNSTIADSTLVSND 279

Query: 543 TMSGYLLTVTARDGG------VPSLS--DTT--------DVEISVVDVNDNEPVFKQQLY 586
                L     R G       VP  S  D T        ++E+ + D+NDN P F++   
Sbjct: 280 AYWYSLFLAETRKGKLVVRQPVPKGSRLDATIENPVRMFNIEVEITDINDNAPHFRRGTM 339

Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT----- 641
             +I E + VG   S   A D DVG N    Y L   +     F I+  +G   T     
Sbjct: 340 HLDISESSSVGERFSLNNAADPDVGSNSVKDYHLSASEH----FSINIQTGRDGTKFADL 395

Query: 642 --NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699
              KALDRE  A H+L   A+DGG P ++          D+ND+ P          + EN
Sbjct: 396 ILTKALDREMQAVHNLILTAVDGGVPTRT----------DMNDNHPEISIKSFQSPVKEN 445

Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK-AELVTMVDLDYES 758
             + T I  +   D D G N VV   I    D   F L  RQ SD   ELV    LD E 
Sbjct: 446 IDVETVIAVVSVSDKDSGDNGVVDLHI---PDKMPFKL--RQSSDNYYELVVSEPLDREK 500

Query: 759 PRKKYEL---VIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR 815
              +Y++   V    SPPL ++  + + + DVNDN P            ++  P      
Sbjct: 501 V-PEYDITFTVTDRGSPPLSDNETMTLELLDVNDNVPRFPQSFYTIRVTENNAPGALLSS 559

Query: 816 VPAYDADVTDK--LQYRILSGNNAN 838
           + A+D D+ +   L Y IL    AN
Sbjct: 560 LTAFDPDLHENQYLVYFILEKEIAN 584



 Score = 87.8 bits (208), Expect = 4e-15
 Identities = 64/201 (31%), Positives = 97/201 (48%), Gaps = 12/201 (5%)

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRET 543
            GT+V  V A D D   NA+++Y +  + S E   +    F+ IN +TG I   K  D ET
Sbjct: 2522 GTSVFAVKAFDRDENDNARVSYHILRDGSPE---NKLTSFLNINSETGDILALKSFDFET 2578

Query: 544  MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT-------ANIMEDALV 596
            +  +   V A D G PSLS    V++ ++D NDN PV    + +         I  +   
Sbjct: 2579 LKTFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNA 2638

Query: 597  GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
            G  V++V A DAD+G NG + + L  +  +   F +D  +G IRT ++      A H L 
Sbjct: 2639 GHLVTKVRAYDADIGYNGWLLFALQ-EVSDHSLFGLDRYTGQIRTLRSFTETDEAEHKLV 2697

Query: 657  AVAIDGGTPPQSSTVIVHIKI 677
             +  D G    S+T  V +K+
Sbjct: 2698 ILVKDNGNVSLSATATVLVKL 2718



 Score = 82.6 bits (195), Expect = 1e-13
 Identities = 55/191 (28%), Positives = 99/191 (51%), Gaps = 18/191 (9%)

Query: 174  IKATDADVGANSAIRYAII-GGNTQMQFS----IDSLSGDVSLVKTLDYEQVRSYRLVIR 228
            +KA D D   N+ + Y I+  G+ + + +    I+S +GD+  +K+ D+E +++++  + 
Sbjct: 2528 VKAFDRDENDNARVSYHILRDGSPENKLTSFLNINSETGDILALKSFDFETLKTFQFQVV 2587

Query: 229  AQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ-------ESVSENVPIGYSIVRVQA 281
            A D GSPS S+   + + I D NDNAP     +         E +  NV  G+ + +V+A
Sbjct: 2588 ASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVRA 2647

Query: 282  YDADEGVNAELTYTMTD-KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD 340
            YDAD G N  L + + +  D++        +D  +G + T        +A+++L++   D
Sbjct: 2648 YDADIGYNGWLLFALQEVSDHS-----LFGLDRYTGQIRTLRSFTETDEAEHKLVILVKD 2702

Query: 341  GGDPPRSATAT 351
             G+   SATAT
Sbjct: 2703 NGNVSLSATAT 2713



 Score = 75.8 bits (178), Expect = 2e-11
 Identities = 61/219 (27%), Positives = 100/219 (45%), Gaps = 22/219 (10%)

Query: 34   EGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRID 93
            E    GT+V  +KA D+D   NA V Y I     D  +PE+           +     I+
Sbjct: 2517 EANQPGTSVFAVKAFDRDENDNARVSYHI---LRDG-SPENK----------LTSFLNIN 2562

Query: 94   GRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN-----YP 148
              +G +L   S D E +  +   V A+D  SP    LSS  T+ V I+D NDN     YP
Sbjct: 2563 SETGDILALKSFDFETLKTFQFQVVASDSGSP---SLSSNVTVKVFILDQNDNAPVILYP 2619

Query: 149  QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
              S  +     +   +V    ++ K++A DAD+G N  + +A+   +    F +D  +G 
Sbjct: 2620 VSSNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTGQ 2679

Query: 209  VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            +  +++        ++LVI  +D G+ S S T  +L+ +
Sbjct: 2680 IRTLRSFTETDEAEHKLVILVKDNGNVSLSATATVLVKL 2718



 Score = 73.7 bits (173), Expect = 7e-11
 Identities = 47/155 (30%), Positives = 74/155 (47%), Gaps = 7/155 (4%)

Query: 96  SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSE--K 153
           +G L    + D E    +   ++A D  SP    LSS  T+H+ I+D NDN P      +
Sbjct: 43  NGNLYALKTFDYEIEKEFLFHIEARDSGSPP---LSSNVTVHIVIVDQNDNAPVIVSPWR 99

Query: 154 TYTVSVDEDI--SVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSL 211
                V+E I  S     ++AK+ A D D   NS I Y ++       FS+D  +G++  
Sbjct: 100 AQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQLLQVTDATLFSLDQYNGEIRT 159

Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           ++   Y   R  RLV+ A+D G P+ S T  + ++
Sbjct: 160 MRMFSYRDPRHQRLVVVAKDNGDPALSATVTIKLS 194



 Score = 67.7 bits (158), Expect = 4e-09
 Identities = 47/152 (30%), Positives = 72/152 (47%), Gaps = 10/152 (6%)

Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP------RFYT 259
           +G++  +KT DYE  + +   I A+D GSP  S+   + I I D NDNAP      R   
Sbjct: 43  NGNLYALKTFDYEIEKEFLFHIEARDSGSPPLSSNVTVHIVIVDQNDNAPVIVSPWRAQG 102

Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319
           S+ +E +  +   G  + +V A D D   N+ +TY +       +  L  ++D  +G + 
Sbjct: 103 SVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQLLQ---VTDATL-FSLDQYNGEIR 158

Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
           T            +L+V A D GDP  SAT T
Sbjct: 159 TMRMFSYRDPRHQRLVVVAKDNGDPALSATVT 190



 Score = 64.5 bits (150), Expect = 4e-08
 Identities = 48/153 (31%), Positives = 70/153 (45%), Gaps = 7/153 (4%)

Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT- 587
           + G +   K  D E    +L  + ARD G P LS    V I +VD NDN PV        
Sbjct: 42  ENGNLYALKTFDYEIEKEFLFHIEARDSGSPPLSSNVTVHIVIVDQNDNAPVIVSPWRAQ 101

Query: 588 ANIMEDAL-----VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642
            +++E+ +      G+ V++V A D D   N RI Y+L  +  +   F +D  +G IRT 
Sbjct: 102 GSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQL-LQVTDATLFSLDQYNGEIRTM 160

Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675
           +           L  VA D G P  S+TV + +
Sbjct: 161 RMFSYRDPRHQRLVVVAKDNGDPALSATVTIKL 193



 Score = 61.7 bits (143), Expect = 3e-07
 Identities = 48/157 (30%), Positives = 75/157 (47%), Gaps = 11/157 (7%)

Query: 597  GTSVSQVGATDADVGLNGRIHYEL----DPKDREEGSFVIDPASGVIRTNKALDRESVAT 652
            GTSV  V A D D   N R+ Y +     P+++      I+  +G I   K+ D E++ T
Sbjct: 2522 GTSVFAVKAFDRDENDNARVSYHILRDGSPENKLTSFLNINSETGDILALKSFDFETLKT 2581

Query: 653  HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF----ESDCLTFYISE---NSPIGTT 705
               + VA D G+P  SS V V + I D ND+ PV      S+     + E   N   G  
Sbjct: 2582 FQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHL 2641

Query: 706  IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
            + ++RA+D D G N  + ++++   D + F L+   G
Sbjct: 2642 VTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTG 2678



 Score = 60.5 bits (140), Expect = 7e-07
 Identities = 60/211 (28%), Positives = 98/211 (46%), Gaps = 21/211 (9%)

Query: 377  EDEPPGTPVVTLTATDADE-DN-RLHYEIT-GGNTRGRFS--ITSQNGRGLITVAQPLDF 431
            E   PGT V  + A D DE DN R+ Y I   G+   + +  +   +  G I   +  DF
Sbjct: 2517 EANQPGTSVFAVKAFDRDENDNARVSYHILRDGSPENKLTSFLNINSETGDILALKSFDF 2576

Query: 432  KQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVF---ENAPYTASVFEDAP--- 483
            +  + +   V A+DSG  S      V++ I D N+ APV     ++  +A   E+ P   
Sbjct: 2577 ETLKTFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNV 2636

Query: 484  -IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
              G  V  V A D+D+G N  + ++L  E+S+ ++      F ++  TG I T +     
Sbjct: 2637 NAGHLVTKVRAYDADIGYNGWLLFALQ-EVSDHSL------FGLDRYTGQIRTLRSFTET 2689

Query: 543  TMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
              + + L +  +D G  SLS T  V + +V+
Sbjct: 2690 DEAEHKLVILVKDNGNVSLSATATVLVKLVE 2720



 Score = 57.6 bits (133), Expect = 5e-06
 Identities = 33/103 (32%), Positives = 58/103 (56%), Gaps = 4/103 (3%)

Query: 695  YISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-KGGDDSNSFSLETRQGSDKAELVTMVD 753
            YI  N P GT++  ++A D DE  NA V Y I + G   N  +      S+  +++ +  
Sbjct: 2515 YIEANQP-GTSVFAVKAFDRDENDNARVSYHILRDGSPENKLTSFLNINSETGDILALKS 2573

Query: 754  LDYESPRK-KYELVIR-AASPPLWNDVRVEILVTDVNDNAPVM 794
             D+E+ +  ++++V   + SP L ++V V++ + D NDNAPV+
Sbjct: 2574 FDFETLKTFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVI 2616



 Score = 43.2 bits (97), Expect = 0.11
 Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 2/95 (2%)

Query: 258  YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY-TMTDKDYTGNVDLPITIDPRSG 316
            Y S  +  +  N P G S+  V+A+D DE  NA ++Y  + D      +   + I+  +G
Sbjct: 2508 YRSGDKRYIEANQP-GTSVFAVKAFDRDENDNARVSYHILRDGSPENKLTSFLNINSETG 2566

Query: 317  WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
             +      D ET   +Q  V A+D G P  S+  T
Sbjct: 2567 DILALKSFDFETLKTFQFQVVASDSGSPSLSSNVT 2601



 Score = 39.1 bits (87), Expect = 1.7
 Identities = 41/197 (20%), Positives = 81/197 (41%), Gaps = 11/197 (5%)

Query: 737 LETRQGSDKAELVTMVDLDYESPRK-KYELVIR-AASPPLWNDVRVEILVTDVNDNAPVM 794
           L +   ++   L  +   DYE  ++  + +  R + SPPL ++V V I++ D NDNAPV+
Sbjct: 35  LRSFYSAENGNLYALKTFDYEIEKEFLFHIEARDSGSPPLSSNVTVHIVIVDQNDNAPVI 94

Query: 795 -----KDFQIIFNNYKDCFPVGPF-GRVPAYDADV--TDKLQYRILSGNNANLILLNETT 846
                    ++          G    +V A D D     ++ Y++L   +A L  L++  
Sbjct: 95  VSPWRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQLLQVTDATLFSLDQYN 154

Query: 847 GSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAE 906
           G +      +   P+   + V   D   +      ++++L T E  + + +         
Sbjct: 155 GEIRTMRMFSYRDPRHQRLVVVAKDN-GDPALSATVTIKLSTVETAVKAYSDMTEVPLEY 213

Query: 907 QFLSPLLGFFIDGLAAI 923
              S L  + + GL ++
Sbjct: 214 DIFSDLNLYLVIGLGSV 230


>UniRef50_UPI00004F6742 Cluster: protocadherin 1 gamma 32; n=3;
           Danio rerio|Rep: protocadherin 1 gamma 32 - Danio rerio
          Length = 961

 Score =  229 bits (559), Expect = 1e-57
 Identities = 179/609 (29%), Positives = 285/609 (46%), Gaps = 34/609 (5%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F +D  SGAL+ + ++DRE +    +      Q S + + L   + + + I+D NDN PQ
Sbjct: 92  FNVDLTSGALVIKETMDREILCGGRLHCHIRIQIS-LQNPLEMHS-VSIEIVDVNDNAPQ 149

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD- 208
           F  +  ++ V E  +           A D DVG NS +R   +  N      ID+ S   
Sbjct: 150 FQSQNTSLEVSE--AAAPGTSFRLESAHDPDVGVNS-LRAYYLSQNDCFILKIDTKSDGS 206

Query: 209 ----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
               + L K LD E++  YRL++ A DGGS  +S  + + INI DVNDNAP F     + 
Sbjct: 207 KIPILVLNKPLDREKMSEYRLILTAVDGGSAEKSGNSAVFINILDVNDNAPHFLNPTKRV 266

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
           ++ EN P G  +  + A DAD G N E++YT  DK    +V    ++D  +G +  +G +
Sbjct: 267 TLLENSPHGTLVTLLNASDADHGQNGEISYTF-DKYTPDSVLKLFSVDSVTGEIRVTGLI 325

Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
           D E    + + V A D G PP   +                         ++ED   GT 
Sbjct: 326 DHELAKVHDVTVLARDKGMPPMEGSCNIKIEIIDVNDNTPEISINMVSSVISEDVTLGTV 385

Query: 385 VVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP--LDFKQERRYVLT 440
           +  +   D D  ++  ++  I  G     F I+S   +GL T+     LD +    Y +T
Sbjct: 386 IALIKVKDEDTGKNGEVNLHIPYGLP---FKISSPY-KGLFTLMADGLLDREAVAEYTIT 441

Query: 441 VSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498
           V+ATDSG   RS      + ++D N+  P+F    Y+  + E+      +L VSA+D DV
Sbjct: 442 VTATDSGSPPRSSQKSFVLCLSDVNDNPPIFSQPSYSVDIAENNAPNAPLLSVSASDPDV 501

Query: 499 GINAQITYSLSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETMSGYLLTVTARDGG 557
           G N+ I++S+   + +EA+      +V INP +G I   +  D E ++ +   V  +D G
Sbjct: 502 GENSTISFSI---LESEALGLSVSSYVYINPNSGQIYAIRKFDYEHLNAFQFVVQVQDRG 558

Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN------IMEDALVGTSVSQVGATDADVG 611
            PS S    V + + D ND+ P+      T++      I   A +G  V+++   D D G
Sbjct: 559 TPSQSSNATVHVFIKDQNDHPPILIYPAPTSDGTLHFFIPRTASIGHLVNRITFVDGDSG 618

Query: 612 LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE-SVATHDLKAVAIDGGTPPQSST 670
            N  + Y +   D E   F ID  +G +RT + L  E S +   L  +  D G P +S++
Sbjct: 619 HNAWLFYSILGPDAE--MFHIDAHTGELRTAQKLSEEDSKSVFSLNVIVKDNGRPSRSAS 676

Query: 671 VIVHIKIED 679
           V V+I + +
Sbjct: 677 VAVNITLAE 685



 Score =  212 bits (517), Expect = 1e-52
 Identities = 176/596 (29%), Positives = 269/596 (45%), Gaps = 38/596 (6%)

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLV--IRAQDG-GSPSRSNTTQLLINI 247
           II  +    F++D  SG + + +T+D E +   RL   IR Q    +P   ++    I I
Sbjct: 83  IISESNDKYFNVDLTSGALVIKETMDREILCGGRLHCHIRIQISLQNPLEMHSVS--IEI 140

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD-YTGNVD 306
            DVNDNAP+F +      VSE    G S     A+D D GVN+   Y ++  D +   +D
Sbjct: 141 VDVNDNAPQFQSQNTSLEVSEAAAPGTSFRLESAHDPDVGVNSLRAYYLSQNDCFILKID 200

Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
              +   +   +  +  LDRE  ++Y+L++TA DGG   +S  +               F
Sbjct: 201 TK-SDGSKIPILVLNKPLDREKMSEYRLILTAVDGGSAEKSGNSAVFINILDVNDNAPHF 259

Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHY---EITGGNTRGRFSITSQNGRG 421
           +     V L E+ P GT V  L A+DAD  ++  + Y   + T  +    FS+ S  G  
Sbjct: 260 LNPTKRVTLLENSPHGTLVTLLNASDADHGQNGEISYTFDKYTPDSVLKLFSVDSVTGE- 318

Query: 422 LITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVF 479
            I V   +D +  + + +TV A D G      +  ++I I D N+  P       ++ + 
Sbjct: 319 -IRVTGLIDHELAKVHDVTVLARDKGMPPMEGSCNIKIEIIDVNDNTPEISINMVSSVIS 377

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           ED  +GT + ++   D D G N ++   +   +  +  + +   F +         + LL
Sbjct: 378 EDVTLGTVIALIKVKDEDTGKNGEVNLHIPYGLPFKISSPYKGLFTL-------MADGLL 430

Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
           DRE ++ Y +TVTA D G P  S      + + DVNDN P+F Q  Y+ +I E+      
Sbjct: 431 DREAVAEYTITVTATDSGSPPRSSQKSFVLCLSDVNDNPPIFSQPSYSVDIAENNAPNAP 490

Query: 600 VSQVGATDADVGLNGRIHY---ELDPKDREEGSFV-IDPASGVIRTNKALDRESVATHDL 655
           +  V A+D DVG N  I +   E +       S+V I+P SG I   +  D E +     
Sbjct: 491 LLSVSASDPDVGENSTISFSILESEALGLSVSSYVYINPNSGQIYAIRKFDYEHLNAFQF 550

Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF-----ESD-CLTFYISENSPIGTTIGEI 709
                D GTP QSS   VH+ I+D ND PP+       SD  L F+I   + IG  +  I
Sbjct: 551 VVQVQDRGTPSQSSNATVHVFIKDQNDHPPILIYPAPTSDGTLHFFIPRTASIGHLVNRI 610

Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765
              D D G NA + YSI  G D+  F ++   G    EL T   L  E  +  + L
Sbjct: 611 TFVDGDSGHNAWLFYSIL-GPDAEMFHIDAHTG----ELRTAQKLSEEDSKSVFSL 661



 Score =  196 bits (479), Expect = 5e-48
 Identities = 162/592 (27%), Positives = 266/592 (44%), Gaps = 58/592 (9%)

Query: 4   PFCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
           P  +H   I ++D ND++P F+ Q     V E A+ GT+     A D D+G N+      
Sbjct: 130 PLEMHSVSIEIVDVNDNAPQFQSQNTSLEVSEAAAPGTSFRLESAHDPDVGVNS------ 183

Query: 63  ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122
             + A  L+  D             D      +   L+    LDREK++ Y +++ A D 
Sbjct: 184 --LRAYYLSQNDCFILKI-------DTKSDGSKIPILVLNKPLDREKMSEYRLILTAVDG 234

Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
            S      S  + + +NI+D NDN P F   T  V++ E  +     ++  + A+DAD G
Sbjct: 235 GSA---EKSGNSAVFINILDVNDNAPHFLNPTKRVTLLE--NSPHGTLVTLLNASDADHG 289

Query: 183 ANSAIRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239
            N  I Y        +    FS+DS++G++ +   +D+E  + + + + A+D G P    
Sbjct: 290 QNGEISYTFDKYTPDSVLKLFSVDSVTGEIRVTGLIDHELAKVHDVTVLARDKGMPPMEG 349

Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
           +  + I I DVNDN P    ++    +SE+V +G  I  ++  D D G N E+   +   
Sbjct: 350 SCNIKIEIIDVNDNTPEISINMVSSVISEDVTLGTVIALIKVKDEDTGKNGEVNLHIP-- 407

Query: 300 DYTGNVDLPITI-DPRSG--WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
                  LP  I  P  G   +   G LDRE  A+Y + VTATD G PPRS+  +     
Sbjct: 408 -----YGLPFKISSPYKGLFTLMADGLLDREAVAEYTITVTATDSGSPPRSSQKSFVLCL 462

Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSI 414
                    F    Y V++AE+  P  P+++++A+D D  E++ + + I      G  S+
Sbjct: 463 SDVNDNPPIFSQPSYSVDIAENNAPNAPLLSVSASDPDVGENSTISFSILESEALG-LSV 521

Query: 415 TS----QNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPV 468
           +S        G I   +  D++    +   V   D G   +S  A V + I D N++ P+
Sbjct: 522 SSYVYINPNSGQIYAIRKFDYEHLNAFQFVVQVQDRGTPSQSSNATVHVFIKDQNDHPPI 581

Query: 469 FENAPYTAS------VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522
                 T+       +   A IG  V  ++  D D G NA + YS+   +  +A     +
Sbjct: 582 LIYPAPTSDGTLHFFIPRTASIGHLVNRITFVDGDSGHNAWLFYSI---LGPDA-----E 633

Query: 523 QFVINPQTGAI-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
            F I+  TG + T  KL + ++ S + L V  +D G PS S +  V I++ +
Sbjct: 634 MFHIDAHTGELRTAQKLSEEDSKSVFSLNVIVKDNGRPSRSASVAVNITLAE 685



 Score =  180 bits (437), Expect = 7e-43
 Identities = 122/441 (27%), Positives = 215/441 (48%), Gaps = 20/441 (4%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSI-TSQNGRGL- 422
           F      +E++E   PGT     +A D D   N L       N      I T  +G  + 
Sbjct: 150 FQSQNTSLEVSEAAAPGTSFRLESAHDPDVGVNSLRAYYLSQNDCFILKIDTKSDGSKIP 209

Query: 423 -ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVF 479
            + + +PLD ++   Y L ++A D G   +S  + V INI D N+ AP F N     ++ 
Sbjct: 210 ILVLNKPLDREKMSEYRLILTAVDGGSAEKSGNSAVFINILDVNDNAPHFLNPTKRVTLL 269

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           E++P GT V +++A+D+D G N +I+Y+      +  +    + F ++  TG I    L+
Sbjct: 270 ENSPHGTLVTLLNASDADHGQNGEISYTFDKYTPDSVL----KLFSVDSVTGEIRVTGLI 325

Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
           D E    + +TV ARD G+P +  + +++I ++DVNDN P     + ++ I ED  +GT 
Sbjct: 326 DHELAKVHDVTVLARDKGMPPMEGSCNIKIEIIDVNDNTPEISINMVSSVISEDVTLGTV 385

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV--IRTNKALDRESVATHDLKA 657
           ++ +   D D G NG ++  + P        +  P  G+  +  +  LDRE+VA + +  
Sbjct: 386 IALIKVKDEDTGKNGEVNLHI-PYGLPFK--ISSPYKGLFTLMADGLLDREAVAEYTITV 442

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
            A D G+PP+SS     + + D+ND+PP+F     +  I+EN+     +  + A DPD G
Sbjct: 443 TATDSGSPPRSSQKSFVLCLSDVNDNPPIFSQPSYSVDIAENNAPNAPLLSVSASDPDVG 502

Query: 718 PNAVVHYSIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPP 773
            N+ + +SI   +    S S       +  ++  +   DYE     ++ V++     +P 
Sbjct: 503 ENSTISFSILESEALGLSVSSYVYINPNSGQIYAIRKFDYEH-LNAFQFVVQVQDRGTPS 561

Query: 774 LWNDVRVEILVTDVNDNAPVM 794
             ++  V + + D ND+ P++
Sbjct: 562 QSSNATVHVFIKDQNDHPPIL 582



 Score =  167 bits (406), Expect = 4e-39
 Identities = 123/376 (32%), Positives = 177/376 (47%), Gaps = 17/376 (4%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           V I I D N+ AP F++   +  V E A  GT+  + SA D DVG+N+   Y LS    N
Sbjct: 136 VSIEIVDVNDNAPQFQSQNTSLEVSEAAAPGTSFRLESAHDPDVGVNSLRAYYLSQ---N 192

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
           +             +   +  NK LDRE MS Y L +TA DGG    S  + V I+++DV
Sbjct: 193 DCFILKIDTKSDGSKIPILVLNKPLDREKMSEYRLILTAVDGGSAEKSGNSAVFINILDV 252

Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP--KDREEGSFVI 632
           NDN P F        ++E++  GT V+ + A+DAD G NG I Y  D    D     F +
Sbjct: 253 NDNAPHFLNPTKRVTLLENSPHGTLVTLLNASDADHGQNGEISYTFDKYTPDSVLKLFSV 312

Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692
           D  +G IR    +D E    HD+  +A D G PP   +  + I+I D+ND+ P    + +
Sbjct: 313 DSVTGEIRVTGLIDHELAKVHDVTVLARDKGMPPMEGSCNIKIEIIDVNDNTPEISINMV 372

Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752
           +  ISE+  +GT I  I+  D D G N  V+  I  G     F + +     K     M 
Sbjct: 373 SSVISEDVTLGTVIALIKVKDEDTGKNGEVNLHIPYG---LPFKISSPY---KGLFTLMA 426

Query: 753 D--LDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC 807
           D  LD E+   +Y + + A    SPP  +     + ++DVNDN P+        +  ++ 
Sbjct: 427 DGLLDREAV-AEYTITVTATDSGSPPRSSQKSFVLCLSDVNDNPPIFSQPSYSVDIAENN 485

Query: 808 FPVGPFGRVPAYDADV 823
            P  P   V A D DV
Sbjct: 486 APNAPLLSVSASDPDV 501



 Score =  157 bits (382), Expect = 3e-36
 Identities = 135/471 (28%), Positives = 205/471 (43%), Gaps = 40/471 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           IN+LD ND++P F       ++ E +  GT V  L A+D D G+N E+ YT +  T D+ 
Sbjct: 247 INILDVNDNAPHFLNPTKRVTLLENSPHGTLVTLLNASDADHGQNGEISYTFDKYTPDS- 305

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                          V  +F +D  +G +     +D E    + V V A D+  P    +
Sbjct: 306 ---------------VLKLFSVDSVTGEIRVTGLIDHELAKVHDVTVLARDKGMP---PM 347

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             +  I + IID NDN P+ S    +  + ED  VT   VIA IK  D D G N  +   
Sbjct: 348 EGSCNIKIEIIDVNDNTPEISINMVSSVISED--VTLGTVIALIKVKDEDTGKNGEVNLH 405

Query: 191 IIGGNTQMQFSIDS-LSGDVSLVK--TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
           I  G   + F I S   G  +L+    LD E V  Y + + A D GSP RS+    ++ +
Sbjct: 406 IPYG---LPFKISSPYKGLFTLMADGLLDREAVAEYTITVTATDSGSPPRSSQKSFVLCL 462

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NVD 306
            DVNDN P F    +   ++EN      ++ V A D D G N+ +++++ + +  G +V 
Sbjct: 463 SDVNDNPPIFSQPSYSVDIAENNAPNAPLLSVSASDPDVGENSTISFSILESEALGLSVS 522

Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
             + I+P SG +Y   + D E    +Q +V   D G P +S+ AT               
Sbjct: 523 SYVYINPNSGQIYAIRKFDYEHLNAFQFVVQVQDRGTPSQSSNATVHVFIKDQNDHPPIL 582

Query: 367 M------PGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQN 418
           +       G     +      G  V  +T  D D  +   L Y I G +    F I +  
Sbjct: 583 IYPAPTSDGTLHFFIPRTASIGHLVNRITFVDGDSGHNAWLFYSILGPDAE-MFHIDAHT 641

Query: 419 GRGLITVAQPLDFKQERR-YVLTVSATDSGGRSDTAMVQINITDANNYAPV 468
           G   +  AQ L  +  +  + L V   D+G  S +A V +NIT A   + V
Sbjct: 642 GE--LRTAQKLSEEDSKSVFSLNVIVKDNGRPSRSASVAVNITLAEKSSDV 690


>UniRef50_Q8IGX4 Cluster: RE10062p; n=6; Diptera|Rep: RE10062p -
           Drosophila melanogaster (Fruit fly)
          Length = 1820

 Score =  229 bits (559), Expect = 1e-57
 Identities = 224/806 (27%), Positives = 351/806 (43%), Gaps = 81/806 (10%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           VF +D  +G +  R  LDRE      V++  TD+    ++  + +    + +   NDN P
Sbjct: 67  VFSVDRETGVVRLRQELDRETQDTVEVIISITDEGIYGTEPNTVSQRRVIPVRYYNDNQP 126

Query: 149 QFSEKTYTVSVDEDISV-TDNPVIAKIKATDADVGANSAIRYAIIGGNT--------QMQ 199
            F  + YT SV E + V ++  V   I   D D G NS ++   +  N          ++
Sbjct: 127 TFLGRPYTASVSESLPVGSELSVEPPIVVVDRDEGINSEVQMKCLEENDICDIFEVRAVK 186

Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR-SNTTQLLINIRDVNDNAPRFY 258
            S  + +  V+L + LD+E   SY L I A D    +R S+   + IN+ D+ D  P F 
Sbjct: 187 ISDGNYTARVALKQQLDFESRPSYILTISASDSALDNRLSSLATISINVIDIQDQPPIFT 246

Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV 318
            + +  +V EN P G SI+ V+A D D G+  E+  ++ D+ + G+ +L    DPR G  
Sbjct: 247 NAPYSATVPENTPAGVSILTVKAVDGDVGIPREIFLSLEDEPF-GHFELVPFGDPRDGTA 305

Query: 319 Y---TSGQLDRETQ------AKYQLLVTAT---DGGDPPRSATATXXXXXXXXXXXXXXF 366
               TS  LDRE          Y   + AT   DG  P   +                 F
Sbjct: 306 VLQTTSEPLDRENAEILQNGGVYVFSIRATELIDGAIPAEHSLTRVTIVVTDVDDHQPTF 365

Query: 367 MPGQYEVELAEDEPPGTPV--VTLTATDADEDNRLHYEITGG---NTRGRFSI--TSQNG 419
               + V + E+   G P+  +++   D D      YE++     N    F +  T   G
Sbjct: 366 SGPHFNVSITENLANGMPLPGLSIFVDDRDMGENSRYELSLRDVFNAARVFEVSPTESQG 425

Query: 420 RGLITV----AQPLDFK----QERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN 471
           R  + V    A  LD+       R++   + A+  G       V+I++ DAN+ APVF+ 
Sbjct: 426 RTPVVVKVLNASRLDYDVVDPDLRKFEFDLVASVKGVEKAKTRVEIHLLDANDNAPVFDQ 485

Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
             Y  +  E+ P+   +  V ATD D G    + Y L    ++         F +NP+TG
Sbjct: 486 GTYRFTAAENLPVDAIIGHVKATDLDSGEFGHVRYVLKGFGADN--------FYVNPETG 537

Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
            +   K LD E  S Y LTV A DGG    +   ++ + V DVNDN P F+ + Y+  I 
Sbjct: 538 GVYLLKPLDYEKQSSYSLTVVAIDGGQREAN--ANLFVGVTDVNDNHPNFESKEYSRTIR 595

Query: 592 EDALVGTSVSQVGATDADVGL--NGRIHYELDPKDREEGS-FVIDPASGVIRTNKA---L 645
           E A +      V A DAD     NGR+ Y +  ++   G+ F I+P +G I   KA   +
Sbjct: 596 EGAALFEPQFFVRAHDADGPSQGNGRVKYSIVSENSIAGNVFRIEPDTGEIVIQKAARSM 655

Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY---------- 695
           D E    ++L   A D G PP S+T  V +++    +  P+F                  
Sbjct: 656 DTER-GEYELVVSATDFGIPPLSNTTRVLVRVGISGNQRPIFRGHFQNMENLPIIGPPSY 714

Query: 696 ---ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752
              I EN+  G+ +  + AHDPD G ++++ Y I G +D+  F ++   G         +
Sbjct: 715 RVSIPENAAAGSNVTSVSAHDPD-GLDSLLRYRIVGANDN--FEIDEISGLITVSPQARI 771

Query: 753 DLDYESPRKKYELVIRAASP----PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY-KDC 807
           D D  S    +E+++ A       P      V + V D+ND  P  +  Q  +  Y  + 
Sbjct: 772 DRD--SNMNSFEIIVNAVDSGTPIPETATTTVYVNVKDINDERPKFE--QNSYATYVSER 827

Query: 808 FPVGPFG-RVPAYDADVTDKLQYRIL 832
             VG    RV A D D+  KL+Y ++
Sbjct: 828 TAVGESVLRVKAIDKDLNSKLEYSMV 853



 Score =  219 bits (536), Expect = 7e-55
 Identities = 242/920 (26%), Positives = 405/920 (44%), Gaps = 114/920 (12%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGK--NAEVEYTIELVTAD 68
            + V D ND+ P FE ++Y  ++REGA+       ++A D D     N  V+Y+I  V+ +
Sbjct: 573  VGVTDVNDNHPNFESKEYSRTIREGAALFEPQFFVRAHDADGPSQGNGRVKYSI--VSEN 630

Query: 69   TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRA---SLDREKVARYTVLVKATDQASP 125
            ++                 +VFRI+  +G ++ +    S+D E+   Y ++V ATD   P
Sbjct: 631  SI---------------AGNVFRIEPDTGEIVIQKAARSMDTER-GEYELVVSATDFGIP 674

Query: 126  VSDRLSSTATIHVNI-IDDN------------DNYPQFSEKTYTVSVDEDISVTDNPVIA 172
                LS+T  + V + I  N            +N P     +Y VS+ E+ +   N  + 
Sbjct: 675  P---LSNTTRVLVRVGISGNQRPIFRGHFQNMENLPIIGPPSYRVSIPENAAAGSN--VT 729

Query: 173  KIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG--DVSLVKTLDYEQ-VRSYRLVIRA 229
             + A D D G +S +RY I+G N    F ID +SG   VS    +D +  + S+ +++ A
Sbjct: 730  SVSAHDPD-GLDSLLRYRIVGANDN--FEIDEISGLITVSPQARIDRDSNMNSFEIIVNA 786

Query: 230  QDGGSP-SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV 288
             D G+P   + TT + +N++D+ND  P+F  + +   VSE   +G S++RV+A D D  +
Sbjct: 787  VDSGTPIPETATTTVYVNVKDINDERPKFEQNSYATYVSERTAVGESVLRVKAIDKD--L 844

Query: 289  NAELTYTMTDK-DYTGNVDLPIT------------IDPRSGWVYTSGQLDRETQAKYQLL 335
            N++L Y+M      T    + I             +D +SG ++ +G L  +  A     
Sbjct: 845  NSKLEYSMVGPVAATTKAGVSIANRSNYRLQEAFRVDSQSGEIFVNGTLRHDVAAIIIFT 904

Query: 336  VTATDGG---DPPRSATATXXXXXXXXXXXXXXFMPGQ--------YEVELAEDEPPGTP 384
            V   D     DP      T                            +V++ E+ P  + 
Sbjct: 905  VGVRDLNAEVDPEGQVDTTEVTVYVQSFQDTNPVFKNTGWTSSRPVIDVKIKEEMPIDSA 964

Query: 385  VVTLTATDADEDNRL-HYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ----ERRYVL 439
            +  L A D      +  +E+        F +  + G   + + + LD++        + L
Sbjct: 965  LFILQAEDPVTRQPITSFELIEPKQVDYFQVAERTGE--VILKKRLDYEALGDTGPEFEL 1022

Query: 440  TVSATDSGG-RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498
             V A  +   RS  + V I + + N+ +P FE   Y A++ E+ P    V+ V A D D 
Sbjct: 1023 QVRANSADRQRSTVSRVNITVENVNDNSPRFERNSYQATIIENRPHPERVIRVRALDKDA 1082

Query: 499  GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI--TTNKLLDRETMSGYLLTVTARDG 556
             +NA+       +I       H   F IN  TG I   + + +DRE      L + A D 
Sbjct: 1083 VLNARDERLGYHKIIYSLQGEHAMLFDINNTTGEIIVASGQTIDRERTPRIQLQIKAEDS 1142

Query: 557  -GVPS--LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613
             G P+       +++I V+DVNDN P F Q+ Y+  I E+A + + V Q+ A DAD GL 
Sbjct: 1143 PGRPTDAKQSVVELQIEVLDVNDNAPEFTQKKYSTVIPENAQIDSFVLQLEAVDADEGLG 1202

Query: 614  GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA-THDLKAVAIDGGT-----PPQ 667
            G + YEL  +    G F ID  SG+I T + L  +  A  + L   A D G      P  
Sbjct: 1203 GEVRYELVNEGEANGLFKIDTKSGLISTRRNLTGKGRAHPYVLIVRAQDNGNQMPKQPTL 1262

Query: 668  SSTVIVHIKIEDI--NDSPPVFESDCL--TFYISENSPIGTTIGEIRAHDPDE--GPNAV 721
            S+   V I I D+  ND  P F S  +     ++EN+  G  + ++ A DPD+   P+  
Sbjct: 1263 STDTDVRIYIGDVSANDGVPYFLSPRVGQMANVTENAVTGAPVFQVIASDPDDESTPSGT 1322

Query: 722  VHYSI-KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA--SPPLWNDV 778
            + Y I     D+ +F ++   G     + T   +D E+ +  Y +++  +    P  +  
Sbjct: 1323 ITYRILPDTPDAEAFVIDAHSGL----ITTRQSMDRET-KDMYRILLEVSDNGQPKQSAT 1377

Query: 779  RV-EILVTDVNDNAPVM---KDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDK--LQYRI 831
            R+ +I + DV+D+ P          +  + ++  P G   G   A D D+ +   + Y I
Sbjct: 1378 RILQIAILDVDDHEPRFAREAGAGPLSMSVREEEPAGTIVGNFSALDEDLGENAAIDYVI 1437

Query: 832  LSGNNANLILLNETTGSMTL 851
            + GNN  L  +     S+ +
Sbjct: 1438 IDGNNEQLFTIERNNESLAI 1457



 Score =  217 bits (530), Expect = 4e-54
 Identities = 210/761 (27%), Positives = 338/761 (44%), Gaps = 67/761 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +NV D ND  P FE   Y   V E  + G +VL +KA D+D+  N+++EY++    A T 
Sbjct: 803  VNVKDINDERPKFEQNSYATYVSERTAVGESVLRVKAIDKDL--NSKLEYSMVGPVAAT- 859

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS-DR 129
              +            +Q+ FR+D +SG +    +L  +  A     V   D  + V  + 
Sbjct: 860  -TKAGVSIANRSNYRLQEAFRVDSQSGEIFVNGTLRHDVAAIIIFTVGVRDLNAEVDPEG 918

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE-DISVTDN-PVIAKIKATDAD--VGANS 185
               T  + V +    D  P F    +T S    D+ + +  P+ + +    A+  V    
Sbjct: 919  QVDTTEVTVYVQSFQDTNPVFKNTGWTSSRPVIDVKIKEEMPIDSALFILQAEDPVTRQP 978

Query: 186  AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV----RSYRLVIRAQDGGSPSRSNTT 241
               + +I       F +   +G+V L K LDYE +      + L +RA +     RS  +
Sbjct: 979  ITSFELIEPKQVDYFQVAERTGEVILKKRLDYEALGDTGPEFELQVRA-NSADRQRSTVS 1037

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA---ELTYTMTD 298
            ++ I + +VNDN+PRF  + +Q ++ EN P    ++RV+A D D  +NA    L Y    
Sbjct: 1038 RVNITVENVNDNSPRFERNSYQATIIENRPHPERVIRVRALDKDAVLNARDERLGYHKII 1097

Query: 299  KDYTGNVDLPITIDPRSG-WVYTSGQ-LDRETQAKYQLLVTATDGGDPP---RSATATXX 353
                G   +   I+  +G  +  SGQ +DRE   + QL + A D    P   + +     
Sbjct: 1098 YSLQGEHAMLFDINNTTGEIIVASGQTIDRERTPRIQLQIKAEDSPGRPTDAKQSVVELQ 1157

Query: 354  XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITG-GNTRG 410
                        F   +Y   + E+    + V+ L A DADE     + YE+   G   G
Sbjct: 1158 IEVLDVNDNAPEFTQKKYSTVIPENAQIDSFVLQLEAVDADEGLGGEVRYELVNEGEANG 1217

Query: 411  RFSITSQNGRGLITVAQPLDFK-QERRYVLTVSATDSGGR--------SDT-AMVQINIT 460
             F I +++  GLI+  + L  K +   YVL V A D+G +        +DT   + I   
Sbjct: 1218 LFKIDTKS--GLISTRRNLTGKGRAHPYVLIVRAQDNGNQMPKQPTLSTDTDVRIYIGDV 1275

Query: 461  DANNYAPVF--ENAPYTASVFEDAPIGTTVLVVSATDSD--VGINAQITYSLSSEISNEA 516
             AN+  P F        A+V E+A  G  V  V A+D D     +  ITY +  +  +  
Sbjct: 1276 SANDGVPYFLSPRVGQMANVTENAVTGAPVFQVIASDPDDESTPSGTITYRILPDTPDA- 1334

Query: 517  VAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVND 576
                 + FVI+  +G ITT + +DRET   Y + +   D G P  S T  ++I+++DV+D
Sbjct: 1335 -----EAFVIDAHSGLITTRQSMDRETKDMYRILLEVSDNGQPKQSATRILQIAILDVDD 1389

Query: 577  NEPVFKQQL----YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632
            +EP F ++      + ++ E+   GT V    A D D+G N  I Y +   + E+  F I
Sbjct: 1390 HEPRFAREAGAGPLSMSVREEEPAGTIVGNFSALDEDLGENAAIDYVIIDGNNEQ-LFTI 1448

Query: 633  D---PASGVIRTNKALDRESVATHDLKAVAIDGGTP-------PQSSTVIVHIKIE---- 678
            +    +  +++T K +DRE V +  L    +  G P       P     + H++I     
Sbjct: 1449 ERNNESLAILKTKKPIDREQVESFTLTIKCLKLGEPGYKFIGDPYDRQDLSHLRINVRVL 1508

Query: 679  DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-EGP 718
            DI+D+ P FE    T  I  N PI T +  ++A D D E P
Sbjct: 1509 DIDDNLPKFEQPDPTVGIRINVPIDTVVTTLKASDADAEAP 1549



 Score =  200 bits (488), Expect = 4e-49
 Identities = 210/763 (27%), Positives = 337/763 (44%), Gaps = 81/763 (10%)

Query: 17  NDHSPVFEMQQYEASVREGASSGTTVLT---LKATDQDIGKNAEVEYTIELVTADTLNPE 73
           ND+ P F  + Y ASV E    G+ +     +   D+D G N+EV+          L   
Sbjct: 122 NDNQPTFLGRPYTASVSESLPVGSELSVEPPIVVVDRDEGINSEVQMKC-------LEEN 174

Query: 74  DAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSST 133
           D           + D       +  +  +  LD E    Y + + A+D A  + +RLSS 
Sbjct: 175 DICDIFEVRAVKISD----GNYTARVALKQQLDFESRPSYILTISASDSA--LDNRLSSL 228

Query: 134 ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG 193
           ATI +N+ID  D  P F+   Y+ +V E+     +  I  +KA D DVG    I  ++  
Sbjct: 229 ATISINVIDIQDQPPIFTNAPYSATVPENTPAGVS--ILTVKAVDGDVGIPREIFLSLED 286

Query: 194 ---GNTQMQFSIDSLSGDVSLVKT---LDYEQVRS------YRLVIRAQ---DGGSPSRS 238
              G+ ++    D   G   L  T   LD E          Y   IRA    DG  P+  
Sbjct: 287 EPFGHFELVPFGDPRDGTAVLQTTSEPLDRENAEILQNGGVYVFSIRATELIDGAIPAEH 346

Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY--DADEGVNAELTYTM 296
           + T++ I + DV+D+ P F    F  S++EN+  G  +  +  +  D D G N+    ++
Sbjct: 347 SLTRVTIVVTDVDDHQPTFSGPHFNVSITENLANGMPLPGLSIFVDDRDMGENSRYELSL 406

Query: 297 TDKDYTGNVD--LPITIDPRSGWVY---TSGQLDRETQ----AKYQLLVTATDGGDPPRS 347
            D      V    P     R+  V     + +LD +       K++  + A+  G     
Sbjct: 407 RDVFNAARVFEVSPTESQGRTPVVVKVLNASRLDYDVVDPDLRKFEFDLVASVKG--VEK 464

Query: 348 ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYE-ITGG 406
           A                 F  G Y    AE+ P    +  + ATD D     H   +  G
Sbjct: 465 AKTRVEIHLLDANDNAPVFDQGTYRFTAAENLPVDAIIGHVKATDLDSGEFGHVRYVLKG 524

Query: 407 NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYA 466
                F +  + G   + + +PLD++++  Y LTV A D G R   A + + +TD N+  
Sbjct: 525 FGADNFYVNPETGG--VYLLKPLDYEKQSSYSLTVVAIDGGQREANANLFVGVTDVNDNH 582

Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI--NAQITYSLSSEISNEAVAHHDQQF 524
           P FE+  Y+ ++ E A +      V A D+D     N ++ YS+ SE S   +A +   F
Sbjct: 583 PNFESKEYSRTIREGAALFEPQFFVRAHDADGPSQGNGRVKYSIVSENS---IAGN--VF 637

Query: 525 VINPQTGAITTNKLL-DRETMSG-YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582
            I P TG I   K     +T  G Y L V+A D G+P LS+TT V + V    +  P+F+
Sbjct: 638 RIEPDTGEIVIQKAARSMDTERGEYELVVSATDFGIPPLSNTTRVLVRVGISGNQRPIFR 697

Query: 583 QQL-------------YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629
                           Y  +I E+A  G++V+ V A D D GL+  + Y +   +    +
Sbjct: 698 GHFQNMENLPIIGPPSYRVSIPENAAAGSNVTSVSAHDPD-GLDSLLRYRIVGAN---DN 753

Query: 630 FVIDPASGVIRTNKA--LDRES-VATHDLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPP 685
           F ID  SG+I  +    +DR+S + + ++   A+D GTP P+++T  V++ ++DIND  P
Sbjct: 754 FEIDEISGLITVSPQARIDRDSNMNSFEIIVNAVDSGTPIPETATTTVYVNVKDINDERP 813

Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
            FE +    Y+SE + +G ++  ++A D D   N+ + YS+ G
Sbjct: 814 KFEQNSYATYVSERTAVGESVLRVKAIDKD--LNSKLEYSMVG 854



 Score =  196 bits (477), Expect = 1e-47
 Identities = 235/944 (24%), Positives = 402/944 (42%), Gaps = 127/944 (13%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I++LD ND++PVF+   Y  +  E       +  +KATD D G+   V Y ++   AD 
Sbjct: 470  EIHLLDANDNAPVFDQGTYRFTAAENLPVDAIIGHVKATDLDSGEFGHVRYVLKGFGADN 529

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                                F ++  +G +     LD EK + Y++ V A D       +
Sbjct: 530  --------------------FYVNPETGGVYLLKPLDYEKQSSYSLTVVAID-----GGQ 564

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
              + A + V + D NDN+P F  K Y+ ++ E  ++ +     +    D     N  ++Y
Sbjct: 565  REANANLFVGVTDVNDNHPNFESKEYSRTIREGAALFEPQFFVRAHDADGPSQGNGRVKY 624

Query: 190  AIIGGNT--QMQFSIDSLSGDVSLVK---TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
            +I+  N+     F I+  +G++ + K   ++D E+   Y LV+ A D G P  SNTT++L
Sbjct: 625  SIVSENSIAGNVFRIEPDTGEIVIQKAARSMDTER-GEYELVVSATDFGIPPLSNTTRVL 683

Query: 245  I------NIRDV-------NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE 291
            +      N R +        +N P      ++ S+ EN   G ++  V A+D D G+++ 
Sbjct: 684  VRVGISGNQRPIFRGHFQNMENLPIIGPPSYRVSIPENAAAGSNVTSVSAHDPD-GLDSL 742

Query: 292  LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ--LDRETQA-KYQLLVTATDGGDP-PRS 347
            L Y +   +   N +    ID  SG +  S Q  +DR++    ++++V A D G P P +
Sbjct: 743  LRYRIVGAN--DNFE----IDEISGLITVSPQARIDRDSNMNSFEIIVNAVDSGTPIPET 796

Query: 348  ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITG-- 405
            AT T              F    Y   ++E    G  V+ + A D D +++L Y + G  
Sbjct: 797  ATTTVYVNVKDINDERPKFEQNSYATYVSERTAVGESVLRVKAIDKDLNSKLEYSMVGPV 856

Query: 406  -GNTRGRFSITSQNG------------RGLITVAQPLDFKQERRYVLTV------SATDS 446
               T+   SI +++              G I V   L        + TV      +  D 
Sbjct: 857  AATTKAGVSIANRSNYRLQEAFRVDSQSGEIFVNGTLRHDVAAIIIFTVGVRDLNAEVDP 916

Query: 447  GGRSDTAMVQINITDANNYAPVFENAPYTAS-------VFEDAPIGTTVLVVSATDSDVG 499
             G+ DT  V + +    +  PVF+N  +T+S       + E+ PI + + ++ A D    
Sbjct: 917  EGQVDTTEVTVYVQSFQDTNPVFKNTGWTSSRPVIDVKIKEEMPIDSALFILQAEDP--- 973

Query: 500  INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM--SGYLLTVTARDGG 557
            +  Q   S    I  + V +    F +  +TG +   K LD E +  +G    +  R   
Sbjct: 974  VTRQPITSFEL-IEPKQVDY----FQVAERTGEVILKKRLDYEALGDTGPEFELQVRANS 1028

Query: 558  VPSLSDTTD-VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR- 615
                  T   V I+V +VNDN P F++  Y A I+E+      V +V A D D  LN R 
Sbjct: 1029 ADRQRSTVSRVNITVENVNDNSPRFERNSYQATIIENRPHPERVIRVRALDKDAVLNARD 1088

Query: 616  ----IHYELDPKDREEGS-FVIDPASG--VIRTNKALDRESVATHDLKAVAIDG-GTPPQ 667
                 H  +     E    F I+  +G  ++ + + +DRE      L+  A D  G P  
Sbjct: 1089 ERLGYHKIIYSLQGEHAMLFDINNTTGEIIVASGQTIDRERTPRIQLQIKAEDSPGRPTD 1148

Query: 668  SSTVIVHIKIE--DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
            +   +V ++IE  D+ND+ P F     +  I EN+ I + + ++ A D DEG    V Y 
Sbjct: 1149 AKQSVVELQIEVLDVNDNAPEFTQKKYSTVIPENAQIDSFVLQLEAVDADEGLGGEVRYE 1208

Query: 726  -IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA--------ASPPLWN 776
             +  G+ +  F ++T+ G     + T  +L  +     Y L++RA          P L  
Sbjct: 1209 LVNEGEANGLFKIDTKSGL----ISTRRNLTGKGRAHPYVLIVRAQDNGNQMPKQPTLST 1264

Query: 777  DVRVEILVTDV--NDNAPVMKDFQI--IFNNYKDCFPVGPFGRVPAYDAD----VTDKLQ 828
            D  V I + DV  ND  P     ++  + N  ++     P  +V A D D     +  + 
Sbjct: 1265 DTDVRIYIGDVSANDGVPYFLSPRVGQMANVTENAVTGAPVFQVIASDPDDESTPSGTIT 1324

Query: 829  YRILSGN-NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            YRIL    +A   +++  +G +T    ++     +  + + V+D
Sbjct: 1325 YRILPDTPDAEAFVIDAHSGLITTRQSMDRETKDMYRILLEVSD 1368



 Score =  182 bits (443), Expect = 1e-43
 Identities = 219/851 (25%), Positives = 348/851 (40%), Gaps = 101/851 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            INV+D  D  P+F    Y A+V E   +G ++LT+KA D D+G   E+  ++E       
Sbjct: 233  INVIDIQDQPPIFTNAPYSATVPENTPAGVSILTVKAVDGDVGIPREIFLSLE------- 285

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLD-REKVARYTVLVKATDQASPVSDR 129
              E             +D   +   +   L R + +  +    Y   ++AT+        
Sbjct: 286  -DEPFGHFELVPFGDPRDGTAVLQTTSEPLDRENAEILQNGGVYVFSIRATELIDGAIPA 344

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
              S   + + + D +D+ P FS   + VS+ E+++         I   D D+G NS    
Sbjct: 345  EHSLTRVTIVVTDVDDHQPTFSGPHFNVSITENLANGMPLPGLSIFVDDRDMGENSRYEL 404

Query: 190  A---IIGGNTQMQFSIDSLSGDVSLV------KTLDYEQV----RSYRLVIRAQDGGSPS 236
            +   +       + S     G   +V        LDY+ V    R +   + A   G   
Sbjct: 405  SLRDVFNAARVFEVSPTESQGRTPVVVKVLNASRLDYDVVDPDLRKFEFDLVASVKGVEK 464

Query: 237  RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
                T++ I++ D NDNAP F    ++ + +EN+P+   I  V+A D D G    + Y +
Sbjct: 465  AK--TRVEIHLLDANDNAPVFDQGTYRFTAAENLPVDAIIGHVKATDLDSGEFGHVRYVL 522

Query: 297  TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
              K +  +      ++P +G VY    LD E Q+ Y L V A DGG   R A A      
Sbjct: 523  --KGFGAD---NFYVNPETGGVYLLKPLDYEKQSSYSLTVVAIDGGQ--REANANLFVGV 575

Query: 357  XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD----EDNRLHYEITGGNT-RGR 411
                     F   +Y   + E      P   + A DAD     + R+ Y I   N+  G 
Sbjct: 576  TDVNDNHPNFESKEYSRTIREGAALFEPQFFVRAHDADGPSQGNGRVKYSIVSENSIAGN 635

Query: 412  -FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPV 468
             F I    G  +I  A      +   Y L VSATD G    S+T  V + +  + N  P+
Sbjct: 636  VFRIEPDTGEIVIQKAARSMDTERGEYELVVSATDFGIPPLSNTTRVLVRVGISGNQRPI 695

Query: 469  F-------ENAP------YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515
            F       EN P      Y  S+ E+A  G+ V  VSA D D G+++ + Y +     N 
Sbjct: 696  FRGHFQNMENLPIIGPPSYRVSIPENAAAGSNVTSVSAHDPD-GLDSLLRYRIVGANDNF 754

Query: 516  AVAHHDQQFVINPQTGAITTNKLLDRET-MSGYLLTVTARDGGVP-SLSDTTDVEISVVD 573
             +        ++PQ         +DR++ M+ + + V A D G P   + TT V ++V D
Sbjct: 755  EIDEISGLITVSPQA-------RIDRDSNMNSFEIIVNAVDSGTPIPETATTTVYVNVKD 807

Query: 574  VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL------------- 620
            +ND  P F+Q  Y   + E   VG SV +V A D D  LN ++ Y +             
Sbjct: 808  INDERPKFEQNSYATYVSERTAVGESVLRVKAIDKD--LNSKLEYSMVGPVAATTKAGVS 865

Query: 621  ---DPKDREEGSFVIDPASGVIRTNKALDRESVA----THDLKAVAIDGGTPPQSSTVIV 673
                   R + +F +D  SG I  N  L  +  A    T  ++ +  +     Q  T  V
Sbjct: 866  IANRSNYRLQEAFRVDSQSGEIFVNGTLRHDVAAIIIFTVGVRDLNAEVDPEGQVDTTEV 925

Query: 674  HIKIEDINDSPPVFES-------DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
             + ++   D+ PVF++         +   I E  PI + +  ++A DP      +  + +
Sbjct: 926  TVYVQSFQDTNPVFKNTGWTSSRPVIDVKIKEEMPIDSALFILQAEDP-VTRQPITSFEL 984

Query: 727  KGGDDSNSFSLETRQGSDKAELVTMVDLDYES---PRKKYELVIRAASPPLWNDV--RVE 781
                  + F +  R G    E++    LDYE+      ++EL +RA S         RV 
Sbjct: 985  IEPKQVDYFQVAERTG----EVILKKRLDYEALGDTGPEFELQVRANSADRQRSTVSRVN 1040

Query: 782  ILVTDVNDNAP 792
            I V +VNDN+P
Sbjct: 1041 ITVENVNDNSP 1051



 Score =  169 bits (411), Expect = 1e-39
 Identities = 182/675 (26%), Positives = 294/675 (43%), Gaps = 76/675 (11%)

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
           S+SEN P+G  + +++  D + G    L Y+++     G V    ++D  +G V    +L
Sbjct: 35  SLSENTPVGSPVFQLKGTDPEGG---RLKYSIS-----GPV---FSVDRETGVVRLRQEL 83

Query: 325 DRETQAKYQLLVTATDGG---DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381
           DRETQ   +++++ TD G     P + +                F+   Y   ++E  P 
Sbjct: 84  DRETQDTVEVIISITDEGIYGTEPNTVSQRRVIPVRYYNDNQPTFLGRPYTASVSESLPV 143

Query: 382 GTPVVT---LTATDADE--DNRLHYEITGGNTR------GRFSITSQNGRGLITVAQPLD 430
           G+ +     +   D DE  ++ +  +    N            I+  N    + + Q LD
Sbjct: 144 GSELSVEPPIVVVDRDEGINSEVQMKCLEENDICDIFEVRAVKISDGNYTARVALKQQLD 203

Query: 431 FKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
           F+    Y+LT+SA+DS      S  A + IN+ D  +  P+F NAPY+A+V E+ P G +
Sbjct: 204 FESRPSYILTISASDSALDNRLSSLATISINVIDIQDQPPIFTNAPYSATVPENTPAGVS 263

Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI---TTNKLLDRET- 543
           +L V A D DVGI  +I  SL     +E   H +     +P+ G     TT++ LDRE  
Sbjct: 264 ILTVKAVDGDVGIPREIFLSL----EDEPFGHFELVPFGDPRDGTAVLQTTSEPLDRENA 319

Query: 544 ---MSG--YLLTVTAR---DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
               +G  Y+ ++ A    DG +P+    T V I V DV+D++P F    +  +I E+  
Sbjct: 320 EILQNGGVYVFSIRATELIDGAIPAEHSLTRVTIVVTDVDDHQPTFSGPHFNVSITENLA 379

Query: 596 VGTSVS--QVGATDADVGLNGRIHYELDPKDREEGS--FVIDPASGVIRTN---KALDRE 648
            G  +    +   D D+G N R  YEL  +D    +  F + P     RT    K L+  
Sbjct: 380 NGMPLPGLSIFVDDRDMGENSR--YELSLRDVFNAARVFEVSPTESQGRTPVVVKVLNAS 437

Query: 649 ----SVATHDLKAVAID---GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701
                V   DL+    D        + +   V I + D ND+ PVF+     F  +EN P
Sbjct: 438 RLDYDVVDPDLRKFEFDLVASVKGVEKAKTRVEIHLLDANDNAPVFDQGTYRFTAAENLP 497

Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761
           +   IG ++A D D G    V Y +KG    N F +    G     +  +  LDYE  + 
Sbjct: 498 VDAIIGHVKATDLDSGEFGHVRYVLKGFGADN-FYVNPETGG----VYLLKPLDYEK-QS 551

Query: 762 KYELVIRAASPPLWN-DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD 820
            Y L + A        +  + + VTDVNDN P  +  +      +      P   V A+D
Sbjct: 552 SYSLTVVAIDGGQREANANLFVGVTDVNDNHPNFESKEYSRTIREGAALFEPQFFVRAHD 611

Query: 821 AD----VTDKLQYRILSGNN--ANLILLNETTGSMTLSPQLNTNVPKLATME--VSVTD- 871
           AD       +++Y I+S N+   N+  +   TG + +     +   +    E  VS TD 
Sbjct: 612 ADGPSQGNGRVKYSIVSENSIAGNVFRIEPDTGEIVIQKAARSMDTERGEYELVVSATDF 671

Query: 872 GVNEIKAMMQLSVRL 886
           G+  +    ++ VR+
Sbjct: 672 GIPPLSNTTRVLVRV 686



 Score =  116 bits (279), Expect = 9e-24
 Identities = 104/353 (29%), Positives = 158/353 (44%), Gaps = 37/353 (10%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            +  QI VLD ND++P F  ++Y   + E A   + VL L+A D D G   EV Y  ELV 
Sbjct: 1154 VELQIEVLDVNDNAPEFTQKKYSTVIPENAQIDSFVLQLEAVDADEGLGGEVRY--ELVN 1211

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASL-DREKVARYTVLVKATDQAS- 124
                N                 +F+ID +SG + TR +L  + +   Y ++V+A D  + 
Sbjct: 1212 EGEAN----------------GLFKIDTKSGLISTRRNLTGKGRAHPYVLIVRAQDNGNQ 1255

Query: 125  -PVSDRLSSTATIHVNI--IDDNDNYPQF-SEKTYTVSVDEDISVTDNPVIAKIKATDAD 180
             P    LS+   + + I  +  ND  P F S +   ++   + +VT  PV   I +   D
Sbjct: 1256 MPKQPTLSTDTDVRIYIGDVSANDGVPYFLSPRVGQMANVTENAVTGAPVFQVIASDPDD 1315

Query: 181  VGANS-AIRYAIIGGNTQMQ-FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238
                S  I Y I+      + F ID+ SG ++  +++D E    YR+++   D G P +S
Sbjct: 1316 ESTPSGTITYRILPDTPDAEAFVIDAHSGLITTRQSMDRETKDMYRILLEVSDNGQPKQS 1375

Query: 239  NTTQLLINIRDVNDNAPRFYTSL----FQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294
             T  L I I DV+D+ PRF           SV E  P G  +    A D D G NA + Y
Sbjct: 1376 ATRILQIAILDVDDHEPRFAREAGAGPLSMSVREEEPAGTIVGNFSALDEDLGENAAIDY 1435

Query: 295  TMTDKDYTGNVDLPITIDPRS---GWVYTSGQLDRETQAKYQLLVTATDGGDP 344
             + D    GN +   TI+  +     + T   +DRE    + L +     G+P
Sbjct: 1436 VIID----GNNEQLFTIERNNESLAILKTKKPIDREQVESFTLTIKCLKLGEP 1484



 Score =  106 bits (254), Expect = 1e-20
 Identities = 80/288 (27%), Positives = 136/288 (47%), Gaps = 30/288 (10%)

Query: 88   DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
            + F ID  SG + TR S+DRE    Y +L++ +D   P   + S+T  + + I+D +D+ 
Sbjct: 1335 EAFVIDAHSGLITTRQSMDRETKDMYRILLEVSDNGQP---KQSATRILQIAILDVDDHE 1391

Query: 148  PQFSEKTYTVSVDEDISVTD--NPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205
            P+F+ +     +   +   +    ++    A D D+G N+AI Y II GN +  F+I+  
Sbjct: 1392 PRFAREAGAGPLSMSVREEEPAGTIVGNFSALDEDLGENAAIDYVIIDGNNEQLFTIERN 1451

Query: 206  SGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPS---------RSNTTQLLINIR--DVN 251
            +  ++++KT   +D EQV S+ L I+    G P          R + + L IN+R  D++
Sbjct: 1452 NESLAILKTKKPIDREQVESFTLTIKCLKLGEPGYKFIGDPYDRQDLSHLRINVRVLDID 1511

Query: 252  DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE-----GVNAELT------YTMTDKD 300
            DN P+F        +  NVPI   +  ++A DAD      G++ E        Y  +   
Sbjct: 1512 DNLPKFEQPDPTVGIRINVPIDTVVTTLKASDADAEAPPVGLSIENVTFVPQFYKRSRSL 1571

Query: 301  YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348
              GN+    T++ R+G + T G         + + V A +   P R A
Sbjct: 1572 AVGNLHNLFTLNNRTGELRTGGSFADYVDGYFLMRVMANNSVQPKRQA 1619


>UniRef50_Q9Y5I4 Cluster: Protocadherin alpha C2 precursor; n=23;
           Euteleostomi|Rep: Protocadherin alpha C2 precursor -
           Homo sapiens (Human)
          Length = 1007

 Score =  228 bits (558), Expect = 1e-57
 Identities = 173/584 (29%), Positives = 266/584 (45%), Gaps = 56/584 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ +LD ND+SP F    Y+  V E  + G       A D D+G N+   Y         
Sbjct: 135 EVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTY--------E 186

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
           L+P +              V         L+ R  LDRE+ A + +++ A D   P    
Sbjct: 187 LSPSEHFELDLKPLQENSKVLE-------LVLRKGLDREQAALHHLVLTAVDGGIPAR-- 237

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            S TA I V ++D NDN P F + TY V + ED       ++ K+ A+D D G+N  +RY
Sbjct: 238 -SGTAQISVRVLDTNDNSPAFDQSTYRVQLRED--SPPGTLVVKLNASDPDEGSNGELRY 294

Query: 190 AIIGGNTQMQ---FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           ++    +  +   FSID+ +G+V ++  LDYE+  SY++ ++A D G    +   ++L++
Sbjct: 295 SLSSYTSDRERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVD 354

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
           I DVNDNAP    +     V EN      +  +   D D G N +++  +          
Sbjct: 355 IVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGL-------EAT 407

Query: 307 LPITID--PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
           LP  ++    S  +  SG LDRE  A Y + VTATDGG P  ++  T             
Sbjct: 408 LPFRLNGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPP 467

Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR-------LHYEITGGNTRGRFSITSQ 417
            F+   Y + + E+  PG  + T+ ATD DE          L  EI G       SI S 
Sbjct: 468 SFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSA 527

Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAP--VFENAP 473
           +G   +      D+++ R + +TV A D G    S T    + + D N++AP  ++  + 
Sbjct: 528 SGS--LYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPTST 585

Query: 474 YTASVFE----DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
            +++ FE     AP G  V  V A DSD G NA + Y L+     +        F +   
Sbjct: 586 NSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTSDLDL-------FKVELH 638

Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
           TG I T + +  E+ S + LTV  RD G PSLS +  + ++VVD
Sbjct: 639 TGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVD 682



 Score =  228 bits (557), Expect = 2e-57
 Identities = 177/603 (29%), Positives = 275/603 (45%), Gaps = 27/603 (4%)

Query: 92  IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151
           +D  SGAL     +DRE +       +       ++    + + + V I+D NDN P+F 
Sbjct: 92  LDLTSGALFVNERIDREALCEQRP--RCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFP 149

Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG---- 207
              Y + V E  SV          A D DVGANS   Y +   +   +  +  L      
Sbjct: 150 RPNYQLQVSE--SVAPGARFHIESAQDPDVGANSVQTYEL-SPSEHFELDLKPLQENSKV 206

Query: 208 -DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266
            ++ L K LD EQ   + LV+ A DGG P+RS T Q+ + + D NDN+P F  S ++  +
Sbjct: 207 LELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQL 266

Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI-TIDPRSGWVYTSGQLD 325
            E+ P G  +V++ A D DEG N EL Y+++   YT + +  + +ID  +G V   G LD
Sbjct: 267 REDSPPGTLVVKLNASDPDEGSNGELRYSLS--SYTSDRERQLFSIDASTGEVRVIGGLD 324

Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
            E  + YQ+ V ATD G  P +                   +       + E+  P T V
Sbjct: 325 YEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIV 384

Query: 386 VTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445
             L+  D D        + G      F +        + V+ PLD ++   Y +TV+ATD
Sbjct: 385 AVLSVNDQDSGPNRKVSL-GLEATLPFRLNGFGNSYTLVVSGPLDRERVAVYNITVTATD 443

Query: 446 SGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503
            G    T++  +++ I+D N+  P F    Y+  + E+   G  +  V ATD D   NA+
Sbjct: 444 GGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAE 503

Query: 504 ITYS-LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
           +TYS L  EI    V  +     IN  +G++      D E    + +TV A+D G P LS
Sbjct: 504 VTYSLLEREIQGLPVTSY---VSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLS 560

Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTAN------IMEDALVGTSVSQVGATDADVGLNGRI 616
            T    + VVD+ND+ P       T +      +   A  G  V++V A D+D G N  +
Sbjct: 561 STVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWL 620

Query: 617 HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676
            Y L  +  +   F ++  +G IRT + +  ES +T +L  V  D G P  S++V + + 
Sbjct: 621 FYHL-AQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVA 679

Query: 677 IED 679
           + D
Sbjct: 680 VVD 682



 Score =  183 bits (446), Expect = 5e-44
 Identities = 166/604 (27%), Positives = 279/604 (46%), Gaps = 37/604 (6%)

Query: 309 ITIDPRSGWVYTSGQLDRET--QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
           + +D  SG ++ + ++DRE   + + + L++       P + +A                
Sbjct: 90  LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFP 149

Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADED-NRLH-YEITGG-NTRGRFSITSQNGRGL- 422
            P  Y+++++E   PG      +A D D   N +  YE++   +         +N + L 
Sbjct: 150 RPN-YQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVLE 208

Query: 423 ITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
           + + + LD +Q   + L ++A D G   RS TA + + + D N+ +P F+ + Y   + E
Sbjct: 209 LVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLRE 268

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           D+P GT V+ ++A+D D G N ++ YSLSS  S+       Q F I+  TG +     LD
Sbjct: 269 DSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDR----ERQLFSIDASTGEVRVIGGLD 324

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP-VFKQQLYTANIMEDALVGTS 599
            E  S Y + V A D G   ++    V + +VDVNDN P V    LY+  + E+A   T 
Sbjct: 325 YEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSP-VPENATPNTI 383

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
           V+ +   D D G N ++   L+       +   +  + V+  +  LDRE VA +++   A
Sbjct: 384 VAVLSVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYTLVV--SGPLDRERVAVYNITVTA 441

Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
            DGG P  +S   + ++I DIND+PP F  D  + YI EN+  G  +  ++A DPDE  N
Sbjct: 442 TDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKEN 501

Query: 720 AVVHYS-----IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR--AASP 772
           A V YS     I+G   ++  S+ +  GS    L  +   DYE  R+ +  V      SP
Sbjct: 502 AEVTYSLLEREIQGLPVTSYVSINSASGS----LYAVNSFDYEKFREFFVTVEAQDKGSP 557

Query: 773 PLWNDVRVEILVTDVNDNA-----PVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDK 826
           PL + V   + V D+ND+A     P   +    F       P G    +V A D+D    
Sbjct: 558 PLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQN 617

Query: 827 --LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLS 883
             L Y +   ++ +L  +   TG +  + ++         + V V D G   + A + ++
Sbjct: 618 AWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAIT 677

Query: 884 VRLI 887
           V ++
Sbjct: 678 VAVV 681


>UniRef50_Q9Y5H7 Cluster: Protocadherin alpha 5 precursor; n=15;
           Eutheria|Rep: Protocadherin alpha 5 precursor - Homo
           sapiens (Human)
          Length = 936

 Score =  228 bits (558), Expect = 1e-57
 Identities = 171/617 (27%), Positives = 283/617 (45%), Gaps = 33/617 (5%)

Query: 88  DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
           D+  ++ ++G L   + +DRE++ R     + +     + DR      + V + D NDN 
Sbjct: 72  DLLEVNLQNGILFVNSRIDREELCRRRA--ECSIHLEVIVDRPLQVFHVEVAVKDINDNP 129

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
           P+FS +   + + E   + D+    +  A+D D+GAN+ +RY +   N    F +D  + 
Sbjct: 130 PRFSRQEQRLFILES-RMPDSRFPLE-GASDLDIGANAQLRYRL---NPNEYFDLDVKTN 184

Query: 208 D-------VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260
           +       + L K+LD E+ + +RL++ A DGG P  + T QLLIN+ D NDNAP F  S
Sbjct: 185 EEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKS 244

Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT 320
           ++   + EN P G  ++++ A DADEG+N E+ Y  ++     +V     I+  +G +  
Sbjct: 245 IYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNL-VLDDVKSKFIINSNTGEIKV 303

Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380
           +G+LD E    Y++ + A D    P S                         + + ED P
Sbjct: 304 NGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAP 363

Query: 381 PGTPVVTLTATDADEDNRLHYEITGG---NTRGRFSITSQNGRGLITVAQPLDFKQERRY 437
             T +  ++   +D D+  + ++T     +   +   T +N   L+ +   LD +    Y
Sbjct: 364 LSTVIALISV--SDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLV-LDSALDRESVSVY 420

Query: 438 VLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495
            L V+A D G  S   TA V + + D N+ AP F    YT  V E+ P G  +  VSA D
Sbjct: 421 ELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARD 480

Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555
           +D   NA ++YSL      E          ++ ++G +   + LD E +      V+ARD
Sbjct: 481 ADAQENALVSYSLVERRVGERPL--SSYVSVHAESGKVYALQPLDHEEVELLQFQVSARD 538

Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLY--TANIMEDAL-----VGTSVSQVGATDA 608
            GVP L     +++ V+D NDN P         T   + + +      G  V++V A D 
Sbjct: 539 AGVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDP 598

Query: 609 DVGLNGRIHYELDPKDREEG-SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
           D G N  + YEL P        F +   +G I T ++LD      H L  +  D G PP 
Sbjct: 599 DSGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPL 658

Query: 668 SSTVIVHIKIEDINDSP 684
           ++T  V + + +   +P
Sbjct: 659 TATATVLVSLVESGQAP 675



 Score =  214 bits (523), Expect = 3e-53
 Identities = 165/553 (29%), Positives = 249/553 (45%), Gaps = 37/553 (6%)

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           + ++D+NDN PRF     +  + E+           A D D G NA+L Y +   +Y   
Sbjct: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEY--- 176

Query: 305 VDLPI-TIDPRSGWV--YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
            DL + T +  + ++       LDRE   +++LLV ATDGG P  + T            
Sbjct: 177 FDLDVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDAND 236

Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITG---GNTRGRFSITS 416
               F    Y V L E+ P GT V+ L A+DADE  +  + Y  +     + + +F I S
Sbjct: 237 NAPEFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINS 296

Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPY 474
             G   I V   LD++    Y + + A D      S    V + + D N+  P       
Sbjct: 297 NTGE--IKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTL 354

Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
              V EDAP+ T + ++S +D D G N Q+T SL   +  + V+     +       ++ 
Sbjct: 355 FLPVKEDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYY-------SLV 407

Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
            +  LDRE++S Y L VTARDGG PSL  T  V + V DVNDN P F Q  YT  + E+ 
Sbjct: 408 LDSALDRESVSVYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENN 467

Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPK---DREEGSFV-IDPASGVIRTNKALDRESV 650
             G  +  V A DAD   N  + Y L  +   +R   S+V +   SG +   + LD E V
Sbjct: 468 PPGCHIFTVSARDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEV 527

Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF-------ESDCLTFYISENSPIG 703
                +  A D G PP  S V + + + D ND+ P             ++  +  +   G
Sbjct: 528 ELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAG 587

Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD-YESPRKK 762
             + ++RA DPD G NA + Y ++      S  +  R G    E+ T   LD  E+PR +
Sbjct: 588 HVVAKVRAVDPDSGYNAWLSYELQPA--PGSARIPFRVGLYTGEISTTRSLDETEAPRHR 645

Query: 763 YELVIR-AASPPL 774
             ++++    PPL
Sbjct: 646 LLVLVKDHGEPPL 658



 Score =  192 bits (469), Expect = 9e-47
 Identities = 119/377 (31%), Positives = 196/377 (51%), Gaps = 10/377 (2%)

Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ--INITDANNYAPVFENAPYTASVFE 480
           + + + LD ++ + + L V ATD G    T  VQ  IN+ DAN+ AP F+ + Y   + E
Sbjct: 193 LVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVRLLE 252

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           +AP GT V+ ++A+D+D GIN +I Y  S+ + ++  +    +F+IN  TG I  N  LD
Sbjct: 253 NAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKS----KFIINSNTGEIKVNGELD 308

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
            E  + Y + + A D     LS    V + ++DVNDN P          + EDA + T +
Sbjct: 309 YEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVI 368

Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
           + +  +D D G NG++   L P    +          ++  + ALDRESV+ ++L   A 
Sbjct: 369 ALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLV-LDSALDRESVSVYELVVTAR 427

Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
           DGG+P   +T  V +++ D+ND+ P F     T ++ EN+P G  I  + A D D   NA
Sbjct: 428 DGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQENA 487

Query: 721 VVHYS-IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR-KKYELVIR-AASPPLWND 777
           +V YS ++        S      ++  ++  +  LD+E     ++++  R A  PPL ++
Sbjct: 488 LVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSN 547

Query: 778 VRVEILVTDVNDNAPVM 794
           V +++ V D NDNAP +
Sbjct: 548 VTLQVFVLDENDNAPAL 564



 Score =  154 bits (373), Expect = 4e-35
 Identities = 114/346 (32%), Positives = 164/346 (47%), Gaps = 30/346 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           INVLD ND++P F+   Y   + E A SGT V+ L A+D D G N E+ Y    +  D  
Sbjct: 229 INVLDANDNAPEFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLD-- 286

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                          V+  F I+  +G +     LD E    Y + + A D++   +  L
Sbjct: 287 --------------DVKSKFIINSNTGEIKVNGELDYEDYNSYEINIDAMDKS---TFPL 329

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           S    + V ++D NDN P+ +  T  + V ED  +  + VIA I  +D D GAN  +  +
Sbjct: 330 SGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPL--STVIALISVSDRDSGANGQVTCS 387

Query: 191 IIGGNTQMQFS-IDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
           ++     + F  + +     SLV    LD E V  Y LV+ A+DGGSPS   T  + + +
Sbjct: 388 LM---PHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDGGSPSLWATASVSVEV 444

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            DVNDNAP F    +   V EN P G  I  V A DAD   NA ++Y++ ++   G   L
Sbjct: 445 ADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVER-RVGERPL 503

Query: 308 P--ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
              +++   SG VY    LD E     Q  V+A D G PP  +  T
Sbjct: 504 SSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVT 549



 Score = 57.2 bits (132), Expect = 6e-06
 Identities = 67/281 (23%), Positives = 123/281 (43%), Gaps = 18/281 (6%)

Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV-IDPASGVIRTNKALDR 647
           +I E+A  GT V ++ A D  + L   +        +  G  + ++  +G++  N  +DR
Sbjct: 33  SIPEEAKHGTFVGRI-AQDLGLELAELVPRLFRVASKGRGDLLEVNLQNGILFVNSRIDR 91

Query: 648 ESVATHDLK-AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706
           E +     + ++ ++           V + ++DIND+PP F       +I E+    +  
Sbjct: 92  EELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNPPRFSRQEQRLFILESRMPDSRF 151

Query: 707 GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA---ELVTMVDLDYESPRKKY 763
               A D D G NA + Y +   + +  F L+ +   ++    ELV    LD E  ++  
Sbjct: 152 PLEGASDLDIGANAQLRYRL---NPNEYFDLDVKTNEEETNFLELVLRKSLDREETQEHR 208

Query: 764 ELVIR--AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYD 820
            LVI      P L   V++ I V D NDNAP   D  I      +  P G    ++ A D
Sbjct: 209 LLVIATDGGKPELTGTVQLLINVLDANDNAPEF-DKSIYNVRLLENAPSGTLVIKLNASD 267

Query: 821 AD--VTDKLQY---RILSGNNANLILLNETTGSMTLSPQLN 856
           AD  +  ++ Y    ++  +  +  ++N  TG + ++ +L+
Sbjct: 268 ADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELD 308


>UniRef50_P34616 Cluster: Cadherin-3 precursor; n=13; root|Rep:
            Cadherin-3 precursor - Caenorhabditis elegans
          Length = 3343

 Score =  228 bits (557), Expect = 2e-57
 Identities = 199/751 (26%), Positives = 342/751 (45%), Gaps = 72/751 (9%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            F I    G + T + LD E +  Y   + A            ST+ + +++ D+ND  P+
Sbjct: 1598 FTISPFDGTIFTNSPLDFENIKTYRFNITAG----------KSTSQVIIHVTDENDEAPR 1647

Query: 150  F-SEKTYTVSVDEDISVTDNP-VIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
            F +     + V E++     P +I    A D D G N  + Y+I+ GNT + F+++S +G
Sbjct: 1648 FITGDVVNLKVLEELDTVSYPLIIGSSIAEDLDEGQNGLVTYSILSGNTSL-FAVNSTTG 1706

Query: 208  DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
            D+  +  LD E+   + L+I A+D G PS S T+++LI++ D+NDN P F  S +   +S
Sbjct: 1707 DILSLIPLDREESSLHELLIEAKDAGIPSLSATSKILIHVGDINDNTPEFELSSYFIKIS 1766

Query: 268  ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
            EN  IG  I+R+ A D D+  +AEL Y++   D    + +P  I+  +GW+  +G+++RE
Sbjct: 1767 ENSKIGSKIIRILATDKDK--DAELQYSLESND---EITIPFRINVATGWITVAGKVNRE 1821

Query: 328  TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387
               +++  V  TDG    +S+                       ++ + +       +  
Sbjct: 1822 ENEEFRFFVKVTDG---EKSSKVIVEIHVEDFNDNHPMINDRNSDIFVPDPTRSVEIIHV 1878

Query: 388  LTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447
            +   D D+ + L + +   N        S+NG   IT+  PL    +    + V+ +D  
Sbjct: 1879 INVHDLDKSDHLKFSLNNSNLN-----LSENGE--ITLKSPL----QTAVPVRVTVSDDA 1927

Query: 448  GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507
            G     M  +    +  + PVF     T SV E        L V   + D      I YS
Sbjct: 1928 GHV-AFMEYLFHPHSRKHFPVFVEKLDTVSVREH---DEQELAVFKANGD-----SIRYS 1978

Query: 508  LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG-GVPSLSDTTD 566
            + S  S+    H + +      TG + T   LD E  S  L+ + A        LS  T 
Sbjct: 1979 IVSRCSD----HLEME----KSTGILKTKSSLDAEEYSECLVFIIATTYFDNKPLSTITK 2030

Query: 567  VEISVVDVNDNEPVFKQQLYTANIMEDA---LVGTSVSQVGATDADVGLNGRIHYELDPK 623
              I +VD+NDN P F QQLY  N+ E++   L+G  +++      D+  + R+ YE+   
Sbjct: 2031 ATIKIVDINDNSPRFDQQLYRFNVTENSGPKLIGHVIAR------DIDRSSRVFYEIVGG 2084

Query: 624  DREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS 683
            D      V +  SG I + + LDRE+ + + L   AID G P +     V + + D +D+
Sbjct: 2085 DANHEFMVTE--SGQIESVRDLDRETKSEYHLIVEAIDDGKPRRRGNTTVIVTVLDEDDN 2142

Query: 684  PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
             P F S      + E+  IG  + ++ A D DE  N    + + GG +   F ++   G 
Sbjct: 2143 APRF-SRIFHVEVPEDVRIGEPVIQLSASDADEHSNH--RFELDGGGEGIPFRVDENTG- 2198

Query: 744  DKAELVTMVD-LDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN 802
                +V + D LD+E  ++ Y + ++        +  + + V DVNDNAP+ +  + +F 
Sbjct: 2199 ----MVFVNDSLDFEK-KQSYRIKVKLTDGAWLIETSLFVNVKDVNDNAPIFEKPEYLFI 2253

Query: 803  NYKDCFPVGPFGRVPAYDADVTDKLQYRILS 833
            + ++   +G F      D++   K++Y + S
Sbjct: 2254 SEENSAEIGQF-HASDMDSENNGKIRYSVTS 2283



 Score =  157 bits (380), Expect = 5e-36
 Identities = 168/700 (24%), Positives = 309/700 (44%), Gaps = 67/700 (9%)

Query: 200  FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259
            F+I    G +     LD+E +++YR  I A         +T+Q++I++ D ND APRF T
Sbjct: 1598 FTISPFDGTIFTNSPLDFENIKTYRFNITAG-------KSTSQVIIHVTDENDEAPRFIT 1650

Query: 260  S-LFQESVSENVP-IGYSIVRVQ--AYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315
              +    V E +  + Y ++     A D DEG N  +TY++     +GN  L   ++  +
Sbjct: 1651 GDVVNLKVLEELDTVSYPLIIGSSIAEDLDEGQNGLVTYSIL----SGNTSL-FAVNSTT 1705

Query: 316  GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375
            G + +   LDRE  + ++LL+ A D G P  SAT+               F    Y +++
Sbjct: 1706 GDILSLIPLDREESSLHELLIEAKDAGIPSLSATSKILIHVGDINDNTPEFELSSYFIKI 1765

Query: 376  AEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435
            +E+   G+ ++ + ATD D+D  L Y +   N             G ITVA  ++ ++  
Sbjct: 1766 SENSKIGSKIIRILATDKDKDAELQYSLES-NDEITIPFRINVATGWITVAGKVNREENE 1824

Query: 436  RYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495
             +   V  TD G +S   +V+I++ D N+  P+  +    + +F   P  +  ++     
Sbjct: 1825 EFRFFVKVTD-GEKSSKVIVEIHVEDFNDNHPMINDR--NSDIFVPDPTRSVEIIHVINV 1881

Query: 496  SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555
             D+  +  + +SL++   N +            + G IT    L  +T     +TV+   
Sbjct: 1882 HDLDKSDHLKFSLNNSNLNLS------------ENGEITLKSPL--QTAVPVRVTVSDDA 1927

Query: 556  GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615
            G V  +       +       + PVF ++L T ++ E      +V +         +  R
Sbjct: 1928 GHVAFME-----YLFHPHSRKHFPVFVEKLDTVSVREHDEQELAVFKANGDSIRYSIVSR 1982

Query: 616  IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG-GTPPQSSTVIVH 674
                L+          ++ ++G+++T  +LD E  +   +  +A       P S+     
Sbjct: 1983 CSDHLE----------MEKSTGILKTKSSLDAEEYSECLVFIIATTYFDNKPLSTITKAT 2032

Query: 675  IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734
            IKI DIND+ P F+     F ++ENS     IG + A D D      V Y I GGD ++ 
Sbjct: 2033 IKIVDINDNSPRFDQQLYRFNVTENSG-PKLIGHVIARDIDRSSR--VFYEIVGGDANHE 2089

Query: 735  FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNA 791
            F +     ++  ++ ++ DLD E+ + +Y L++ A     P    +  V + V D +DNA
Sbjct: 2090 FMV-----TESGQIESVRDLDRET-KSEYHLIVEAIDDGKPRRRGNTTVIVTVLDEDDNA 2143

Query: 792  PVMKDFQIIFN-NYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSM 849
            P    F  IF+    +   +G P  ++ A DAD     ++ +  G       ++E TG +
Sbjct: 2144 P---RFSRIFHVEVPEDVRIGEPVIQLSASDADEHSNHRFELDGGGEGIPFRVDENTGMV 2200

Query: 850  TLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889
             ++  L+    +   ++V +TDG   I+  + ++V+ + +
Sbjct: 2201 FVNDSLDFEKKQSYRIKVKLTDGAWLIETSLFVNVKDVND 2240



 Score =  153 bits (370), Expect = 9e-35
 Identities = 191/751 (25%), Positives = 314/751 (41%), Gaps = 70/751 (9%)

Query: 2   SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEV--- 58
           S P  IH  I+VLD ND+SP+F +      + E A  G  V    ATD D GKN  +   
Sbjct: 96  SPPSIIHILIDVLDVNDNSPIFPIDVQRVEIPETAPIGWRVQISGATDPDEGKNGTIGKY 155

Query: 59  EYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVK 118
           E    L T DT++P                + + DG     +T   LDRE    Y++ + 
Sbjct: 156 ELVDSLATVDTMSPFG--------------IVQSDGFLFLEVT-GKLDRETRDLYSMRLT 200

Query: 119 ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178
           A DQ  P    LSS+  +++ I+D NDN P F  ++ T++ +       N  +  + ATD
Sbjct: 201 AIDQGVP---ELSSSCHLNILILDINDNPPNFGIRSLTLNWNG----LPNTKLFSLNATD 253

Query: 179 ADVGANSAIRYAII-GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237
            D   NS + Y I+  G T   FSI   S +  LV   + E ++    V+ A+D G P  
Sbjct: 254 LDSNENSLLTYRILPSGPTSEMFSI---SDENILVTQNNTECLQRCEFVVEARDSGVPPL 310

Query: 238 SNTTQLLINIRDVNDNAP----RFYTSLFQESVSENVPI-GYSIVRVQAYDADEGVNAEL 292
           S T  +++N+   N++ P    RFY S +   + +   + G ++  +   D+D  + A  
Sbjct: 311 STTLNIVVNMEYGNEHEPNINIRFYPSDYPFIIVQPEDVNGKTLAILSITDSDGPLGANS 370

Query: 293 TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSATAT 351
           T  + + +      L   I  +S  + T   ++   Q +Y L   A DG  P  R     
Sbjct: 371 TIWIENGNEQSIFSL---ISRQSINILTVKHVENANQEQYILEFRANDGQSPADRITRKE 427

Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGR 411
                          +  +  V + +D  PG+ V  +     D      +E+   +    
Sbjct: 428 LKIFFKKYVKSTQIHVERESHVTVEKDTVPGSFVAHVETNCTD---MCSFELANSDV--- 481

Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVF-E 470
           F I   NG   I V   +  +    Y L +       R         + +A+ +  V  E
Sbjct: 482 FKIDPFNG---IIVTSSILPEGVTSYHLPI-------RIHLPPPSTQLVEADVFVKVIQE 531

Query: 471 NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
           + P       ++PI         T  DV +   I     ++I   +      +  + P  
Sbjct: 532 SVPKNLIRSSESPIHLKRAYTFTTWQDVSLGTVIGRLPKAQI--YSTIDTVSELGVFPD- 588

Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590
           G++   K +  + ++   L VT  +      S  T   + V  +N + P+   Q+   ++
Sbjct: 589 GSVFVGKTITSDFVT---LPVTLVNRNTTQTSIIT---LIVKPLNQHSPIC--QITEIHV 640

Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGVIRTNKALDRES 649
           +E+A +GT   ++ A D D GL+G + Y+ L   D  +G F +D  SG +R+ KA D E 
Sbjct: 641 LENAPIGTIFGRIQARDEDSGLSGVVSYKILTKSDDYDGIFHLDSTSGSLRSLKAFDAEK 700

Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
             ++  +  A D GTP +++     I IED+ND+ P F S   T  IS  S    T+  +
Sbjct: 701 KRSYTFEYEAKDLGTPSKTTNCPATIFIEDVNDNVPKFGSRYYTATISGKS--NETVAIV 758

Query: 710 RAHDPD-EGPNAVVHYSIKGGDDSNSFSLET 739
           +A+D D +  N  + Y +    D      ET
Sbjct: 759 QANDNDVDVKNQKLQYHLLNYHDFFQLDKET 789



 Score =  135 bits (327), Expect = 1e-29
 Identities = 129/423 (30%), Positives = 196/423 (46%), Gaps = 46/423 (10%)

Query: 146  NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205
            ++P F EK  TVSV E     D   +A  KA         +IRY+I+   +     ++  
Sbjct: 1944 HFPVFVEKLDTVSVREH----DEQELAVFKAN------GDSIRYSIVSRCSD-HLEMEKS 1992

Query: 206  SGDVSLVKTLDYEQVRSYRLVIRAQDG-GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
            +G +    +LD E+     + I A     +   S  T+  I I D+NDN+PRF   L++ 
Sbjct: 1993 TGILKTKSSLDAEEYSECLVFIIATTYFDNKPLSTITKATIKIVDINDNSPRFDQQLYRF 2052

Query: 265  SVSENVPIGYSIV-RVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323
            +V+EN   G  ++  V A D D   ++ + Y +   D   N +  +T    SG + +   
Sbjct: 2053 NVTENS--GPKLIGHVIARDIDR--SSRVFYEIVGGD--ANHEFMVT---ESGQIESVRD 2103

Query: 324  LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383
            LDRET+++Y L+V A D G P R    T              F    + VE+ ED   G 
Sbjct: 2104 LDRETKSEYHLIVEAIDDGKPRRRGNTTVIVTVLDEDDNAPRFSR-IFHVEVPEDVRIGE 2162

Query: 384  PVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443
            PV+ L+A+DADE +   +E+ GG     F +      G++ V   LDF++++ Y + V  
Sbjct: 2163 PVIQLSASDADEHSNHRFELDGGGEGIPFRV--DENTGMVFVNDSLDFEKKQSYRIKVKL 2220

Query: 444  TDSGGRSDTAMVQINITDANNYAPVFENAPYT-ASVFEDAPIGTTVLVVSATDSDVGINA 502
            TD     +T++  +N+ D N+ AP+FE   Y   S    A IG       A+D D   N 
Sbjct: 2221 TDGAWLIETSLF-VNVKDVNDNAPIFEKPEYLFISEENSAEIGQ----FHASDMDSENNG 2275

Query: 503  QITYSLSSEISNEAVAHHDQQFVINPQTGAITT-NKLLDRETMSGYLLTVTARDGGVPSL 561
            +I YS++S             F I P TG ++   + L +  MS   L VTA D GVP L
Sbjct: 2276 KIRYSVTS-----------PYFKIEPSTGVLSRFRQQLPQPLMS---LKVTATDHGVPRL 2321

Query: 562  SDT 564
              T
Sbjct: 2322 QKT 2324



 Score =  131 bits (316), Expect = 3e-28
 Identities = 161/669 (24%), Positives = 284/669 (42%), Gaps = 87/669 (13%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I+V D ND++P FE+  Y   + E +  G+ ++ + ATD+D  K+AE++Y++E       
Sbjct: 1744 IHVGDINDNTPEFELSSYFIKISENSKIGSKIIRILATDKD--KDAELQYSLES------ 1795

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            N E            +   FRI+  +G +     ++RE+   +   VK TD         
Sbjct: 1796 NDE------------ITIPFRINVATGWITVAGKVNREENEEFRFFVKVTDGEK------ 1837

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            SS   + +++ D NDN+P  +++   + V +     +  +I  I   D D   +  ++++
Sbjct: 1838 SSKVIVEIHVEDFNDNHPMINDRNSDIFVPDPTRSVE--IIHVINVHDLD--KSDHLKFS 1893

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            +   N  +     S +G+++L   L  +     R+ + + D G  +     + L +    
Sbjct: 1894 LNNSNLNL-----SENGEITLKSPL--QTAVPVRVTV-SDDAGHVA---FMEYLFHPHS- 1941

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
              + P F   L   SV E+     ++ +       + +   +    +D          + 
Sbjct: 1942 RKHFPVFVEKLDTVSVREHDEQELAVFKANG----DSIRYSIVSRCSDH---------LE 1988

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD-PPRSATATXXXXXXXXXXXXXXFMPG 369
            ++  +G + T   LD E  ++  + + AT   D  P S                  F   
Sbjct: 1989 MEKSTGILKTKSSLDAEEYSECLVFIIATTYFDNKPLSTITKATIKIVDINDNSPRFDQQ 2048

Query: 370  QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
             Y   + E+  P   +  + A D D  +R+ YEI GG+    F +T     G I   + L
Sbjct: 2049 LYRFNVTENSGPKL-IGHVIARDIDRSSRVFYEIVGGDANHEFMVTES---GQIESVRDL 2104

Query: 430  DFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
            D + +  Y L V A D G   R     V + + D ++ AP F    +   V ED  IG  
Sbjct: 2105 DRETKSEYHLIVEAIDDGKPRRRGNTTVIVTVLDEDDNAPRFSRI-FHVEVPEDVRIGEP 2163

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
            V+ +SA+D+D   N +  + L      E +      F ++  TG +  N  LD E    Y
Sbjct: 2164 VIQLSASDADEHSNHR--FELDG--GGEGIP-----FRVDENTGMVFVNDSLDFEKKQSY 2214

Query: 548  LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
             + V   DG    L +T+ + ++V DVNDN P+F++  Y     E++     + Q  A+D
Sbjct: 2215 RIKVKLTDGAW--LIETS-LFVNVKDVNDNAPIFEKPEYLFISEENS---AEIGQFHASD 2268

Query: 608  ADVGLNGRIHYELDPKDREEGSFVIDPASGVI-RTNKALDRESVATHDLKAVAIDGGTPP 666
             D   NG+I Y +         F I+P++GV+ R  + L +  ++   LK  A D G P 
Sbjct: 2269 MDSENNGKIRYSVTSP-----YFKIEPSTGVLSRFRQQLPQPLMS---LKVTATDHGVPR 2320

Query: 667  QSSTVIVHI 675
               TV+ H+
Sbjct: 2321 LQKTVLAHL 2329



 Score =  118 bits (285), Expect = 2e-24
 Identities = 147/551 (26%), Positives = 246/551 (44%), Gaps = 56/551 (10%)

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
           QFSE+T   SV ED  +  N +I  +   +A++G      Y +  GN++++F   +L  +
Sbjct: 26  QFSEETIKFSVSEDAKL--NTIIGHL---EAEIGYT----YRLSRGNSKIKFDEQTL--E 74

Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268
           +S+   LD E   +  ++I        S  +   +LI++ DVNDN+P F   + +  + E
Sbjct: 75  LSVSSPLDRESENAIDMLIIT------SPPSIIHILIDVLDVNDNSPIFPIDVQRVEIPE 128

Query: 269 NVPIGYSIVRVQAYDADEGVNAEL-TYTMTDKDYTGNVDLPITIDPRSGWVY--TSGQLD 325
             PIG+ +    A D DEG N  +  Y + D   T +   P  I    G+++   +G+LD
Sbjct: 129 TAPIGWRVQISGATDPDEGKNGTIGKYELVDSLATVDTMSPFGIVQSDGFLFLEVTGKLD 188

Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
           RET+  Y + +TA D G P  S++                F  G   + L  +  P T +
Sbjct: 189 RETRDLYSMRLTAIDQGVPELSSSCHLNILILDINDNPPNF--GIRSLTLNWNGLPNTKL 246

Query: 386 VTLTATDAD--EDNRLHYEI-TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
            +L ATD D  E++ L Y I   G T   FSI+ +N   ++      +  Q   +V  V 
Sbjct: 247 FSLNATDLDSNENSLLTYRILPSGPTSEMFSISDEN---ILVTQNNTECLQRCEFV--VE 301

Query: 443 ATDSG--GRSDTAMVQINITDANNYAP----VFENAPYTASVFEDAPI-GTTVLVVSATD 495
           A DSG    S T  + +N+   N + P     F  + Y   + +   + G T+ ++S TD
Sbjct: 302 ARDSGVPPLSTTLNIVVNMEYGNEHEPNINIRFYPSDYPFIIVQPEDVNGKTLAILSITD 361

Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555
           SD  + A  T  +  E  NE         +I+ Q+  I T K ++      Y+L   A D
Sbjct: 362 SDGPLGANSTIWI--ENGNEQSIFS----LISRQSINILTVKHVENANQEQYILEFRAND 415

Query: 556 GGVPSLSDT-TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614
           G  P+   T  +++I       +  +  ++     + +D + G+ V+ V     D+    
Sbjct: 416 GQSPADRITRKELKIFFKKYVKSTQIHVERESHVTVEKDTVPGSFVAHVETNCTDM---- 471

Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674
              +EL   D     F IDP +G+I T+  L  E V ++ L  + I    PP +  V   
Sbjct: 472 -CSFELANSD----VFKIDPFNGIIVTSSILP-EGVTSYHL-PIRIH-LPPPSTQLVEAD 523

Query: 675 IKIEDINDSPP 685
           + ++ I +S P
Sbjct: 524 VFVKVIQESVP 534



 Score =  116 bits (278), Expect = 1e-23
 Identities = 108/375 (28%), Positives = 165/375 (44%), Gaps = 38/375 (10%)

Query: 517  VAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVND 576
            +  +D  F I+P  G I TN  LD E +  Y   +TA          T+ V I V D ND
Sbjct: 1591 IQDNDYNFTISPFDGTIFTNSPLDFENIKTYRFNITAG-------KSTSQVIIHVTDEND 1643

Query: 577  NEPVF-KQQLYTANIMED-------ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG 628
              P F    +    ++E+        ++G+S+    A D D G NG + Y +        
Sbjct: 1644 EAPRFITGDVVNLKVLEELDTVSYPLIIGSSI----AEDLDEGQNGLVTYSI--LSGNTS 1697

Query: 629  SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688
             F ++  +G I +   LDRE  + H+L   A D G P  S+T  + I + DIND+ P FE
Sbjct: 1698 LFAVNSTTGDILSLIPLDREESSLHELLIEAKDAGIPSLSATSKILIHVGDINDNTPEFE 1757

Query: 689  SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD-SNSFSLETRQGSDKAE 747
                   ISENS IG+ I  I A D D+  +A + YS++  D+ +  F +    G     
Sbjct: 1758 LSSYFIKISENSKIGSKIIRILATDKDK--DAELQYSLESNDEITIPFRINVATG----- 1810

Query: 748  LVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC 807
             +T+         +++   ++       + V VEI V D NDN P++ D           
Sbjct: 1811 WITVAGKVNREENEEFRFFVKVTDGEKSSKVIVEIHVEDFNDNHPMINDRNSDIFVPDPT 1870

Query: 808  FPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867
              V     +  +D D +D L++ +   NN+NL L     G +TL   L T VP    + V
Sbjct: 1871 RSVEIIHVINVHDLDKSDHLKFSL---NNSNLNL--SENGEITLKSPLQTAVP----VRV 1921

Query: 868  SVTDGVNEIKAMMQL 882
            +V+D    +  M  L
Sbjct: 1922 TVSDDAGHVAFMEYL 1936



 Score =  111 bits (268), Expect = 2e-22
 Identities = 181/743 (24%), Positives = 291/743 (39%), Gaps = 80/743 (10%)

Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI-RYAIIGG 194
           I ++++D NDN P F      V + E   +     I+   ATD D G N  I +Y ++  
Sbjct: 103 ILIDVLDVNDNSPIFPIDVQRVEIPETAPIGWRVQISG--ATDPDEGKNGTIGKYELVDS 160

Query: 195 ----NTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
               +T   F I    G + L  T  LD E    Y + + A D G P  S++  L I I 
Sbjct: 161 LATVDTMSPFGIVQSDGFLFLEVTGKLDRETRDLYSMRLTAIDQGVPELSSSCHLNILIL 220

Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
           D+NDN P F   +   +++ N      +  + A D D   N+ LTY +     T  +   
Sbjct: 221 DINDNPPNF--GIRSLTLNWNGLPNTKLFSLNATDLDSNENSLLTYRILPSGPTSEM--- 275

Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX----X 364
            +I   +  V    Q + E   + + +V A D G PP S T                   
Sbjct: 276 FSISDENILVT---QNNTECLQRCEFVVEARDSGVPPLSTTLNIVVNMEYGNEHEPNINI 332

Query: 365 XFMPGQYEVELAEDEPP-GTPVVTLTATDADEDNRLHYEI--TGGNTRGRFSITSQNGRG 421
            F P  Y   + + E   G  +  L+ TD+D     +  I    GN +  FS+ S+    
Sbjct: 333 RFYPSDYPFIIVQPEDVNGKTLAILSITDSDGPLGANSTIWIENGNEQSIFSLISRQSIN 392

Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
           ++TV    +  QE+ Y+L   A D    +D       IT        F+    +  +  +
Sbjct: 393 ILTVKHVENANQEQ-YILEFRANDGQSPAD------RIT-RKELKIFFKKYVKSTQIHVE 444

Query: 482 APIGTTVLVVSATDSDVG-INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
                TV   +   S V  +    T   S E++N  V      F I+P  G I T+ +L 
Sbjct: 445 RESHVTVEKDTVPGSFVAHVETNCTDMCSFELANSDV------FKIDPFNGIIVTSSILP 498

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVD-------VNDNE-PVFKQQLYTANIME 592
            E ++ Y L +        +     DV + V+        +  +E P+  ++ YT    +
Sbjct: 499 -EGVTSYHLPIRIHLPPPSTQLVEADVFVKVIQESVPKNLIRSSESPIHLKRAYTFTTWQ 557

Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652
           D  +GT + ++           +I+  +D    E G F      G +   K +  + V  
Sbjct: 558 DVSLGTVIGRLP--------KAQIYSTIDTVS-ELGVF----PDGSVFVGKTITSDFVT- 603

Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
             L    ++  T   + T I+ + ++ +N   P+ +      ++ EN+PIGT  G I+A 
Sbjct: 604 --LPVTLVNRNT---TQTSIITLIVKPLNQHSPICQ--ITEIHVLENAPIGTIFGRIQAR 656

Query: 713 DPDEGPNAVVHYSI--KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIR- 768
           D D G + VV Y I  K  D    F L++  GS    L ++   D E  R   +E   + 
Sbjct: 657 DEDSGLSGVVSYKILTKSDDYDGIFHLDSTSGS----LRSLKAFDAEKKRSYTFEYEAKD 712

Query: 769 AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV-TDKL 827
             +P    +    I + DVNDN P                      +    D DV   KL
Sbjct: 713 LGTPSKTTNCPATIFIEDVNDNVPKFGSRYYTATISGKSNETVAIVQANDNDVDVKNQKL 772

Query: 828 QYRILSGNNANLILLNETTGSMT 850
           QY +L  N  +   L++ TG +T
Sbjct: 773 QYHLL--NYHDFFQLDKETGKVT 793



 Score =  103 bits (247), Expect = 7e-20
 Identities = 95/350 (27%), Positives = 153/350 (43%), Gaps = 26/350 (7%)

Query: 401 YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT 460
           Y ++ GN++ +F   +      ++V+ PLD + E    + +  +          + I++ 
Sbjct: 57  YRLSRGNSKIKFDEQTLE----LSVSSPLDRESENAIDMLIITSPPS----IIHILIDVL 108

Query: 461 DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI-TYSLSSEISNEAVAH 519
           D N+ +P+F        + E APIG  V +  ATD D G N  I  Y L   + + A   
Sbjct: 109 DVNDNSPIFPIDVQRVEIPETAPIGWRVQISGATDPDEGKNGTIGKYEL---VDSLATVD 165

Query: 520 HDQQFVINPQTGAI---TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVND 576
               F I    G +    T KL DRET   Y + +TA D GVP LS +  + I ++D+ND
Sbjct: 166 TMSPFGIVQSDGFLFLEVTGKL-DRETRDLYSMRLTAIDQGVPELSSSCHLNILILDIND 224

Query: 577 NEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS 636
           N P F  +  T N   + L  T +  + ATD D   N  + Y + P       F I   +
Sbjct: 225 NPPNFGIRSLTLN--WNGLPNTKLFSLNATDLDSNENSLLTYRILPSGPTSEMFSISDEN 282

Query: 637 GVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP-----VFESDC 691
            ++  N   + E +   +    A D G PP S+T+ + + +E  N+  P      + SD 
Sbjct: 283 ILVTQN---NTECLQRCEFVVEARDSGVPPLSTTLNIVVNMEYGNEHEPNINIRFYPSDY 339

Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741
               +      G T+  +   D D    A     I+ G++ + FSL +RQ
Sbjct: 340 PFIIVQPEDVNGKTLAILSITDSDGPLGANSTIWIENGNEQSIFSLISRQ 389



 Score = 85.8 bits (203), Expect = 2e-14
 Identities = 110/435 (25%), Positives = 185/435 (42%), Gaps = 39/435 (8%)

Query: 468  VFENAPYTASVFEDAPIGTTVL----VVSATDSDVGI---NAQITYSLSSEISNEAVAHH 520
            +++N P     F+D  I   V      V+  D++  +   N  +   ++SEI    +   
Sbjct: 1434 IYDNRPPFKVHFDDVTIEFQVTQKLRAVTCEDAEFWMFFGNEDVGMLIASEIVTWRIVPQ 1493

Query: 521  --DQQFVINPQTGAI-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577
                 F I+P TG I +T        ++   +   + DG      D   + I      +N
Sbjct: 1494 IGSDSFKIDPITGIIQSTPNTKPTSDIAKLKIQAISYDGERVGFCDVK-IHIDKAAFVEN 1552

Query: 578  EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637
              V     +  NI E A   T V ++    A  GL G + + +   D    +F I P  G
Sbjct: 1553 V-VLSNGTFEFNISETADRFTEVGKIVILGA--GLEGSV-FRIQDNDY---NFTISPFDG 1605

Query: 638  VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697
             I TN  LD E++ T+     A        +S VI+H+  E+ +++P     D +   + 
Sbjct: 1606 TIFTNSPLDFENIKTYRFNITA-----GKSTSQVIIHVTDEN-DEAPRFITGDVVNLKVL 1659

Query: 698  ENSPIGT---TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDL 754
            E     +    IG   A D DEG N +V YSI  G+ S  F++ +  G    ++++++ L
Sbjct: 1660 EELDTVSYPLIIGSSIAEDLDEGQNGLVTYSILSGNTS-LFAVNSTTG----DILSLIPL 1714

Query: 755  DYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811
            D E     +EL+I A     P L    ++ I V D+NDN P   +    F    +   +G
Sbjct: 1715 DREES-SLHELLIEAKDAGIPSLSATSKILIHVGDINDNTPEF-ELSSYFIKISENSKIG 1772

Query: 812  P-FGRVPAYDADVTDKLQYRILSGNNANL-ILLNETTGSMTLSPQLNTNVPKLATMEVSV 869
                R+ A D D   +LQY + S +   +   +N  TG +T++ ++N    +     V V
Sbjct: 1773 SKIIRILATDKDKDAELQYSLESNDEITIPFRINVATGWITVAGKVNREENEEFRFFVKV 1832

Query: 870  TDGVNEIKAMMQLSV 884
            TDG    K ++++ V
Sbjct: 1833 TDGEKSSKVIVEIHV 1847



 Score = 83.4 bits (197), Expect = 8e-14
 Identities = 81/287 (28%), Positives = 130/287 (45%), Gaps = 29/287 (10%)

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
            D   TI P  G ++T+  LD E    Y+  +TA         +T+               
Sbjct: 1595 DYNFTISPFDGTIFTNSPLDFENIKTYRFNITA-------GKSTSQVIIHVTDENDEAPR 1647

Query: 366  FMPGQ-YEVELAED-EPPGTPVV--TLTATDADE--DNRLHYEITGGNTRGRFSITSQNG 419
            F+ G    +++ E+ +    P++  +  A D DE  +  + Y I  GNT   F++ S  G
Sbjct: 1648 FITGDVVNLKVLEELDTVSYPLIIGSSIAEDLDEGQNGLVTYSILSGNT-SLFAVNSTTG 1706

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477
              L  +  PLD ++   + L + A D+G    S T+ + I++ D N+  P FE + Y   
Sbjct: 1707 DILSLI--PLDREESSLHELLIEAKDAGIPSLSATSKILIHVGDINDNTPEFELSSYFIK 1764

Query: 478  VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            + E++ IG+ ++ + ATD D   +A++ YSL    SN+ +      F IN  TG IT   
Sbjct: 1765 ISENSKIGSKIIRILATDKDK--DAELQYSLE---SNDEIT---IPFRINVATGWITVAG 1816

Query: 538  LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584
             ++RE    +   V   DG     S    VEI V D NDN P+   +
Sbjct: 1817 KVNREENEEFRFFVKVTDG---EKSSKVIVEIHVEDFNDNHPMINDR 1860



 Score = 69.3 bits (162), Expect = 1e-09
 Identities = 60/187 (32%), Positives = 91/187 (48%), Gaps = 21/187 (11%)

Query: 170 VIAKIKATDADVGANSAIRYAIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVI 227
           +  +I+A D D G +  + Y I+  +      F +DS SG +  +K  D E+ RSY    
Sbjct: 649 IFGRIQARDEDSGLSGVVSYKILTKSDDYDGIFHLDSTSGSLRSLKAFDAEKKRSYTFEY 708

Query: 228 RAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG 287
            A+D G+PS++      I I DVNDN P+F +  +  ++S       ++  VQA D D  
Sbjct: 709 EAKDLGTPSKTTNCPATIFIEDVNDNVPKFGSRYYTATISGK--SNETVAIVQANDNDVD 766

Query: 288 V-NAELTYTM--------TDKDYTGNV----DLPITIDPRSGWVYTSGQLDRE--TQAKY 332
           V N +L Y +         DK+ TG V    D+P+T   R     ++  +D E   Q+K 
Sbjct: 767 VKNQKLQYHLLNYHDFFQLDKE-TGKVTTIQDVPMTWQ-RLNISISAVNMDSERFLQSKT 824

Query: 333 QLLVTAT 339
            LLVT T
Sbjct: 825 FLLVTVT 831



 Score = 66.1 bits (154), Expect = 1e-08
 Identities = 59/198 (29%), Positives = 92/198 (46%), Gaps = 29/198 (14%)

Query: 17  NDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAX 76
           N HSP+ ++   E  V E A  GT    ++A D+D G +  V Y I L  +D  +     
Sbjct: 627 NQHSPICQIT--EIHVLENAPIGTIFGRIQARDEDSGLSGVVSYKI-LTKSDDYD----- 678

Query: 77  XXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATI 136
                       +F +D  SG+L +  + D EK   YT   +A D  +P S   +  ATI
Sbjct: 679 -----------GIFHLDSTSGSLRSLKAFDAEKKRSYTFEYEAKDLGTP-SKTTNCPATI 726

Query: 137 HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA-NSAIRYAIIGGN 195
            +   D NDN P+F  + YT +    IS   N  +A ++A D DV   N  ++Y ++  N
Sbjct: 727 FIE--DVNDNVPKFGSRYYTAT----ISGKSNETVAIVQANDNDVDVKNQKLQYHLL--N 778

Query: 196 TQMQFSIDSLSGDVSLVK 213
               F +D  +G V+ ++
Sbjct: 779 YHDFFQLDKETGKVTTIQ 796



 Score = 64.9 bits (151), Expect = 3e-08
 Identities = 79/317 (24%), Positives = 127/317 (40%), Gaps = 34/317 (10%)

Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640
           F ++    ++ EDA + T +   G  +A++G   R+        R       D  +  + 
Sbjct: 27  FSEETIKFSVSEDAKLNTII---GHLEAEIGYTYRL-------SRGNSKIKFDEQTLELS 76

Query: 641 TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE--DINDSPPVFESDCLTFYISE 698
            +  LDRES    D+  +     +PP     I+HI I+  D+ND+ P+F  D     I E
Sbjct: 77  VSSPLDRESENAIDMLIIT----SPPS----IIHILIDVLDVNDNSPIFPIDVQRVEIPE 128

Query: 699 NSPIGTTIGEIRAHDPDEGPNAVV-HY----SIKGGDDSNSFSLETRQGSDKAELVTMVD 753
            +PIG  +    A DPDEG N  +  Y    S+   D  + F +    G    E+   +D
Sbjct: 129 TAPIGWRVQISGATDPDEGKNGTIGKYELVDSLATVDTMSPFGIVQSDGFLFLEVTGKLD 188

Query: 754 LDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF 813
            +           I    P L +   + IL+ D+NDN P      +  N   +  P    
Sbjct: 189 RETRDLYSMRLTAIDQGVPELSSSCHLNILILDINDNPPNFGIRSLTLN--WNGLPNTKL 246

Query: 814 GRVPAYDADVTDK--LQYRIL-SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVT 870
             + A D D  +   L YRIL SG  + +  +++      L  Q NT   +     V   
Sbjct: 247 FSLNATDLDSNENSLLTYRILPSGPTSEMFSISDEN---ILVTQNNTECLQRCEFVVEAR 303

Query: 871 D-GVNEIKAMMQLSVRL 886
           D GV  +   + + V +
Sbjct: 304 DSGVPPLSTTLNIVVNM 320



 Score = 50.8 bits (116), Expect = 5e-04
 Identities = 55/256 (21%), Positives = 98/256 (38%), Gaps = 15/256 (5%)

Query: 239 NTTQ---LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295
           NTTQ   + + ++ +N ++P     + +  V EN PIG    R+QA D D G++  ++Y 
Sbjct: 612 NTTQTSIITLIVKPLNQHSP--ICQITEIHVLENAPIGTIFGRIQARDEDSGLSGVVSYK 669

Query: 296 MTDK--DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353
           +  K  DY G   L    D  SG + +    D E +  Y     A D G P ++      
Sbjct: 670 ILTKSDDYDGIFHL----DSTSGSLRSLKAFDAEKKRSYTFEYEAKDLGTPSKTTNCPAT 725

Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN-RLHYEITGGNTRGRF 412
                       F    Y   ++        +V     D D  N +L Y +   N    F
Sbjct: 726 IFIEDVNDNVPKFGSRYYTATISGKSNETVAIVQANDNDVDVKNQKLQYHLL--NYHDFF 783

Query: 413 SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENA 472
            +  + G+       P+ +++    +  V+            + + +T ++  A V  N+
Sbjct: 784 QLDKETGKVTTIQDVPMTWQRLNISISAVNMDSERFLQSKTFLLVTVTSSSKLA-VQLNS 842

Query: 473 PYTASVFEDAPIGTTV 488
                +F++  IG  V
Sbjct: 843 GNLIRIFKNDKIGEKV 858


>UniRef50_Q0V9M2 Cluster: Putative uncharacterized protein
           MGC146652; n=1; Xenopus tropicalis|Rep: Putative
           uncharacterized protein MGC146652 - Xenopus tropicalis
           (Western clawed frog) (Silurana tropicalis)
          Length = 911

 Score =  227 bits (556), Expect = 3e-57
 Identities = 179/615 (29%), Positives = 288/615 (46%), Gaps = 33/615 (5%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F +D ++GAL  R  +DRE +   ++      +     ++     ++ + I+D NDN P 
Sbjct: 74  FFVDQKTGALTVRDRIDRESLCGSSLSCLLPLELG--IEKPFELFSVDIEILDVNDNSPS 131

Query: 150 FSEKTYTVSVDEDISVTDNPVI--AKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS- 206
           F      + +   I +  NP +      A D+DVG N   +Y  I  N     S+ +L  
Sbjct: 132 FLSDNQIIQI---IEIFANPGVRFPLDTAEDSDVGINGINQYK-INPNPFFSLSVKNLKD 187

Query: 207 ----GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLF 262
                ++ L K LD E+   + L++ A DGG   RS +T + I + DVNDNAP F    +
Sbjct: 188 GTLIAELVLEKKLDREEKGQHELLLTAFDGGEQPRSGSTLITIIVLDVNDNAPVFDQPSY 247

Query: 263 QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322
           + ++ EN+P+   ++++ A D DEGVNAE++Y       T    +   ++P +G +Y  G
Sbjct: 248 KITLHENLPLTTVVMKLNATDLDEGVNAEISYLFDHHTSTAAKGI-FGLNPNTGEIYIKG 306

Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382
            +D E    Y+L V A DGG P +                    +      E+ ED P G
Sbjct: 307 FVDFEKTHFYELFVKAVDGGTPRQEGRCLIQVEVEDINDNSPEIIFTSNANEVPEDAPIG 366

Query: 383 TPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
           T V  +T  D D       ++ G +    F I     R  +  ++ LD ++  +Y + ++
Sbjct: 367 TVVGFITVRDKDSGKNGDVQL-GVSPDLPFKIQPFKNRYSLVTSEHLDREKTPQYTIQLT 425

Query: 443 ATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
           A+D G    S+  ++ +N++D N+  PVF  + Y A + E+   GT +  VSATD DVG 
Sbjct: 426 ASDLGSPALSNQTVILLNVSDVNDNRPVFSQSVYNAHIKENIEPGTLLCTVSATDPDVGS 485

Query: 501 NAQITYSLS-SEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558
           N+ +TYS+S S+I   +V+     FV IN  TG I   +  D E      +T    D G 
Sbjct: 486 NSDLTYSISESQIDGSSVS----SFVFINSNTGDIYAQRSFDYEQFQVLTITARVEDSGS 541

Query: 559 PSLSDTTDVEISVVDVNDNEPVF------KQQLYTANIMEDALVGTSVSQVGATDADVGL 612
           P L     V I ++D NDN P        K  +    I + A  G  V+++ A D D G 
Sbjct: 542 PKLFSNVSVHIFILDTNDNAPSVLYPGDSKGFIAQEKIPQSASAGYLVTKISAIDPDSGH 601

Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKA-LDRESVATHDLKAVAIDGGTPPQSSTV 671
           N  + Y +  +   +  F I   +G IR  ++ L+ ++   H + +V+ D G P  S+TV
Sbjct: 602 NAWLSYRV-VEPIGQTLFEISQYTGEIRIIRSFLEIDNTEQHLVISVS-DHGEPALSATV 659

Query: 672 IVHI-KIEDINDSPP 685
            V I  +E+I    P
Sbjct: 660 TVIINSVENIAQELP 674



 Score =  196 bits (477), Expect = 1e-47
 Identities = 166/572 (29%), Positives = 252/572 (44%), Gaps = 37/572 (6%)

Query: 180 DVGANSAI----RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRL-VIRAQDGGS 234
           D+G N A     R ++  G     F +D  +G +++   +D E +    L  +   + G 
Sbjct: 50  DLGLNMADIEKRRLSLRSGANGRYFFVDQKTGALTVRDRIDRESLCGSSLSCLLPLELGI 109

Query: 235 PSRSNTTQLLINIRDVNDNAPRFYT-SLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293
                   + I I DVNDN+P F + +   + +      G       A D+D G+N    
Sbjct: 110 EKPFELFSVDIEILDVNDNSPSFLSDNQIIQIIEIFANPGVRFPLDTAEDSDVGINGINQ 169

Query: 294 YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353
           Y +    +       +        +    +LDRE + +++LL+TA DGG+ PRS +    
Sbjct: 170 YKINPNPFFSLSVKNLKDGTLIAELVLEKKLDREEKGQHELLLTAFDGGEQPRSGSTLIT 229

Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED-----NRLHYEITGGNT 408
                       F    Y++ L E+ P  T V+ L ATD DE      + L    T    
Sbjct: 230 IIVLDVNDNAPVFDQPSYKITLHENLPLTTVVMKLNATDLDEGVNAEISYLFDHHTSTAA 289

Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYA 466
           +G F +    G   I +   +DF++   Y L V A D G   +    ++Q+ + D N+ +
Sbjct: 290 KGIFGLNPNTGE--IYIKGFVDFEKTHFYELFVKAVDGGTPRQEGRCLIQVEVEDINDNS 347

Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
           P          V EDAPIGT V  ++  D D G N  +   +S ++           F I
Sbjct: 348 PEIIFTSNANEVPEDAPIGTVVGFITVRDKDSGKNGDVQLGVSPDLP----------FKI 397

Query: 527 NPQTG--AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584
            P     ++ T++ LDRE    Y + +TA D G P+LS+ T + ++V DVNDN PVF Q 
Sbjct: 398 QPFKNRYSLVTSEHLDREKTPQYTIQLTASDLGSPALSNQTVILLNVSDVNDNRPVFSQS 457

Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD---REEGSFV-IDPASGVIR 640
           +Y A+I E+   GT +  V ATD DVG N  + Y +           SFV I+  +G I 
Sbjct: 458 VYNAHIKENIEPGTLLCTVSATDPDVGSNSDLTYSISESQIDGSSVSSFVFINSNTGDIY 517

Query: 641 TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP--VFESDCLTFYISE 698
             ++ D E      + A   D G+P   S V VHI I D ND+ P  ++  D   F   E
Sbjct: 518 AQRSFDYEQFQVLTITARVEDSGSPKLFSNVSVHIFILDTNDNAPSVLYPGDSKGFIAQE 577

Query: 699 NSP----IGTTIGEIRAHDPDEGPNAVVHYSI 726
             P     G  + +I A DPD G NA + Y +
Sbjct: 578 KIPQSASAGYLVTKISAIDPDSGHNAWLSYRV 609



 Score =  182 bits (444), Expect = 1e-43
 Identities = 120/380 (31%), Positives = 191/380 (50%), Gaps = 21/380 (5%)

Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480
           + + + LD +++ ++ L ++A D G   RS + ++ I + D N+ APVF+   Y  ++ E
Sbjct: 194 LVLEKKLDREEKGQHELLLTAFDGGEQPRSGSTLITIIVLDVNDNAPVFDQPSYKITLHE 253

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           + P+ T V+ ++ATD D G+NA+I+Y      S  A       F +NP TG I     +D
Sbjct: 254 NLPLTTVVMKLNATDLDEGVNAEISYLFDHHTSTAAKGI----FGLNPNTGEIYIKGFVD 309

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN---IMEDALVG 597
            E    Y L V A DGG P       +++ V D+NDN P   + ++T+N   + EDA +G
Sbjct: 310 FEKTHFYELFVKAVDGGTPRQEGRCLIQVEVEDINDNSP---EIIFTSNANEVPEDAPIG 366

Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG--VIRTNKALDRESVATHDL 655
           T V  +   D D G NG +   + P    +  F I P      + T++ LDRE    + +
Sbjct: 367 TVVGFITVRDKDSGKNGDVQLGVSP----DLPFKIQPFKNRYSLVTSEHLDREKTPQYTI 422

Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
           +  A D G+P  S+  ++ + + D+ND+ PVF       +I EN   GT +  + A DPD
Sbjct: 423 QLTASDLGSPALSNQTVILLNVSDVNDNRPVFSQSVYNAHIKENIEPGTLLCTVSATDPD 482

Query: 716 EGPNAVVHYSIKGGD-DSNSFSLETRQGSDKAELVTMVDLDYESPRKKY--ELVIRAASP 772
            G N+ + YSI     D +S S      S+  ++      DYE  +       V  + SP
Sbjct: 483 VGSNSDLTYSISESQIDGSSVSSFVFINSNTGDIYAQRSFDYEQFQVLTITARVEDSGSP 542

Query: 773 PLWNDVRVEILVTDVNDNAP 792
            L+++V V I + D NDNAP
Sbjct: 543 KLFSNVSVHIFILDTNDNAP 562



 Score =  162 bits (394), Expect = 1e-37
 Identities = 152/527 (28%), Positives = 232/527 (44%), Gaps = 34/527 (6%)

Query: 366 FMPGQYEVELAEDEPPGTPVVT----LTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421
           ++ GQ    +AE+  PGT V      L    AD + R     +G N  GR+    Q   G
Sbjct: 25  WVSGQLRYSIAEESEPGTLVGNVAQDLGLNMADIEKRRLSLRSGAN--GRYFFVDQK-TG 81

Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGRS---DTAMVQINITDANNYAPVFENAPYTASV 478
            +TV   +D +      L+       G     +   V I I D N+ +P F +      +
Sbjct: 82  ALTVRDRIDRESLCGSSLSCLLPLELGIEKPFELFSVDIEILDVNDNSPSFLSDNQIIQI 141

Query: 479 FED-APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
            E  A  G    + +A DSDVGIN    Y ++    N   +   +          +   K
Sbjct: 142 IEIFANPGVRFPLDTAEDSDVGINGINQYKINP---NPFFSLSVKNLKDGTLIAELVLEK 198

Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
            LDRE    + L +TA DGG    S +T + I V+DVNDN PVF Q  Y   + E+  + 
Sbjct: 199 KLDREEKGQHELLLTAFDGGEQPRSGSTLITIIVLDVNDNAPVFDQPSYKITLHENLPLT 258

Query: 598 TSVSQVGATDADVGLNGRIHYELD--PKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655
           T V ++ ATD D G+N  I Y  D       +G F ++P +G I     +D E    ++L
Sbjct: 259 TVVMKLNATDLDEGVNAEISYLFDHHTSTAAKGIFGLNPNTGEIYIKGFVDFEKTHFYEL 318

Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
              A+DGGTP Q    ++ +++EDIND+ P          + E++PIGT +G I   D D
Sbjct: 319 FVKAVDGGTPRQEGRCLIQVEVEDINDNSPEIIFTSNANEVPEDAPIGTVVGFITVRDKD 378

Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPRKKYELVIR-AASPP 773
            G N  V   +     S     + +   ++  LVT   LD E +P+   +L      SP 
Sbjct: 379 SGKNGDVQLGV-----SPDLPFKIQPFKNRYSLVTSEHLDREKTPQYTIQLTASDLGSPA 433

Query: 774 LWNDVRVEILVTDVNDNAPVMKDFQIIFNNY--KDCFPVGPFGRVPAYDADV--TDKLQY 829
           L N   + + V+DVNDN PV    Q ++N +  ++  P      V A D DV     L Y
Sbjct: 434 LSNQTVILLNVSDVNDNRPVFS--QSVYNAHIKENIEPGTLLCTVSATDPDVGSNSDLTY 491

Query: 830 RI----LSGNN-ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            I    + G++ ++ + +N  TG +      +    ++ T+   V D
Sbjct: 492 SISESQIDGSSVSSFVFINSNTGDIYAQRSFDYEQFQVLTITARVED 538



 Score =  160 bits (389), Expect = 4e-37
 Identities = 131/493 (26%), Positives = 214/493 (43%), Gaps = 37/493 (7%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I VLD ND++PVF+   Y+ ++ E     T V+ L ATD D G NAE+ Y  +  T+   
Sbjct: 230 IIVLDVNDNAPVFDQPSYKITLHENLPLTTVVMKLNATDLDEGVNAEISYLFDHHTS--- 286

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           + +F ++  +G +  +  +D EK   Y + VKA D  +P   R 
Sbjct: 287 -------------TAAKGIFGLNPNTGEIYIKGFVDFEKTHFYELFVKAVDGGTP---RQ 330

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
                I V + D NDN P+    +    V ED  +    V+  I   D D G N  ++  
Sbjct: 331 EGRCLIQVEVEDINDNSPEIIFTSNANEVPEDAPI--GTVVGFITVRDKDSGKNGDVQ-- 386

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            +G +  + F I       SLV +  LD E+   Y + + A D GSP+ SN T +L+N+ 
Sbjct: 387 -LGVSPDLPFKIQPFKNRYSLVTSEHLDREKTPQYTIQLTASDLGSPALSNQTVILLNVS 445

Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NVDL 307
           DVNDN P F  S++   + EN+  G  +  V A D D G N++LTY++++    G +V  
Sbjct: 446 DVNDNRPVFSQSVYNAHIKENIEPGTLLCTVSATDPDVGSNSDLTYSISESQIDGSSVSS 505

Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR-SATATXXXXXXXXXXXXXXF 366
            + I+  +G +Y     D E      +     D G P   S  +                
Sbjct: 506 FVFINSNTGDIYAQRSFDYEQFQVLTITARVEDSGSPKLFSNVSVHIFILDTNDNAPSVL 565

Query: 367 MPGQYEVELAEDEPP-----GTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNG 419
            PG  +  +A+++ P     G  V  ++A D D  +   L Y +     +  F I+   G
Sbjct: 566 YPGDSKGFIAQEKIPQSASAGYLVTKISAIDPDSGHNAWLSYRVVEPIGQTLFEISQYTG 625

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479
             +  +   L+     ++ L +S +D G  + +A V + I    N A    ++       
Sbjct: 626 E-IRIIRSFLEIDNTEQH-LVISVSDHGEPALSATVTVIINSVENIAQELPHSQDMIPHS 683

Query: 480 EDAPIGTTVLVVS 492
           + +P  T  L++S
Sbjct: 684 QTSPNLTLYLIIS 696



 Score =  105 bits (253), Expect = 1e-20
 Identities = 73/277 (26%), Positives = 125/277 (45%), Gaps = 25/277 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           +NV D ND+ PVF    Y A ++E    GT + T+ ATD D+G N+++ Y+I     D  
Sbjct: 442 LNVSDVNDNRPVFSQSVYNAHIKENIEPGTLLCTVSATDPDVGSNSDLTYSISESQID-- 499

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                          V     I+  +G +  + S D E+    T+  +  D  SP   +L
Sbjct: 500 ------------GSSVSSFVFINSNTGDIYAQRSFDYEQFQVLTITARVEDSGSP---KL 544

Query: 131 SSTATIHVNIIDDNDNYPQF----SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
            S  ++H+ I+D NDN P        K +        S +   ++ KI A D D G N+ 
Sbjct: 545 FSNVSVHIFILDTNDNAPSVLYPGDSKGFIAQEKIPQSASAGYLVTKISAIDPDSGHNAW 604

Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
           + Y ++    Q  F I   +G++ ++++ L+ +    + LVI   D G P+ S T  ++I
Sbjct: 605 LSYRVVEPIGQTLFEISQYTGEIRIIRSFLEIDNTEQH-LVISVSDHGEPALSATVTVII 663

Query: 246 N-IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA 281
           N + ++    P     +     S N+ + Y I+ + A
Sbjct: 664 NSVENIAQELPHSQDMIPHSQTSPNLTL-YLIISLVA 699


>UniRef50_UPI0000E821D2 Cluster: PREDICTED: similar to protocadherin
           gamma B5, partial; n=2; Gallus gallus|Rep: PREDICTED:
           similar to protocadherin gamma B5, partial - Gallus
           gallus
          Length = 850

 Score =  227 bits (555), Expect = 3e-57
 Identities = 160/564 (28%), Positives = 263/564 (46%), Gaps = 28/564 (4%)

Query: 197 QMQFSIDSLSGDVSLVKTLDYEQV-RSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP 255
           ++ F++   +G++ + + LD E++ R       + +    +  N   + + I D+NDN+P
Sbjct: 74  KLYFAVSGENGNLYVSERLDREELCRESESCAVSFEAVVQNPLNVFHVEVAIHDINDNSP 133

Query: 256 RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315
            F  ++    + E    G       A D D G N+ LTY +T+ D + ++ + ++   + 
Sbjct: 134 AFSKAVLDLEIGEWTIPGARFPLEVAQDPDVGSNSLLTYQLTE-DSSFSLAMKVSKGGKQ 192

Query: 316 G-WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374
              +     LDRE Q+ +Q+++TATDGGD  +S +                F    Y+ +
Sbjct: 193 QPELVLERALDREKQSSFQMVLTATDGGDSAKSGSVHIRVNVSDANDNAPVFNKNAYDAQ 252

Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT----RGRFSITSQNGRGLITVAQPLD 430
           + E+ P G+ V+ + A DAD  +        GN     R  FSI +++G   +  A PLD
Sbjct: 253 MRENLPVGSLVLQVRAADADAGSNGRVSYFFGNVPESVRSLFSIDAESGE--VRTAGPLD 310

Query: 431 FKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
           F++  +Y   +   D GG +    VQI+I D N+ AP       ++ V EDAP GT V +
Sbjct: 311 FEERSKYSFGLEGRDGGGLTGHCEVQIDIIDENDNAPEITTLSLSSRVPEDAPPGTVVAL 370

Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550
           +   D D G N Q+   LS +   + VA     +        + T   LDRE  S + +T
Sbjct: 371 LKVRDRDSGENGQVRCELSGDTPLQIVASSGGSY-------KVVTAGALDRERASEHRVT 423

Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610
           V A D G P+LS   D+ + V DVNDN PVF++  Y+A + E+   G  V +V A DAD 
Sbjct: 424 VIATDRGSPALSSRADLVLEVSDVNDNAPVFEEAAYSAYVPENNAAGEPVLRVSARDADA 483

Query: 611 GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST 670
           G NGR+ Y L     +     +   +G +   ++ D E      ++  A DGGTP +S+T
Sbjct: 484 GANGRVSYALAGGGADAAFVSVRAETGELYAQRSFDYERCREFSVEVRARDGGTPARSAT 543

Query: 671 VIVHIKIEDINDSPPVF-----------ESDCLTF-YISENSPIGTTIGEIRAHDPDEGP 718
             V + + D ND+ P              +    F  +  ++  G  + ++ A D D G 
Sbjct: 544 ATVRVFVLDRNDNAPRVLWPAAGGAEGGGAGAGPFEVVPRSAEAGYLVAKVVAVDADAGR 603

Query: 719 NAVVHYSIKGGDDSNSFSLETRQG 742
           NA + Y +    +   F +E R G
Sbjct: 604 NAWLSYELLQAPEPALFRVEARSG 627



 Score =  225 bits (549), Expect = 2e-56
 Identities = 184/618 (29%), Positives = 287/618 (46%), Gaps = 46/618 (7%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F + G +G L     LDRE++ R +     + +A  V     +   + V I D NDN P 
Sbjct: 77  FAVSGENGNLYVSERLDREELCRESESCAVSFEA--VVQNPLNVFHVEVAIHDINDNSPA 134

Query: 150 FSEKTYTVSVDE-DISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG- 207
           FS+    + + E  I     P+     A D DVG+NS + Y +   ++       S  G 
Sbjct: 135 FSKAVLDLEIGEWTIPGARFPLEV---AQDPDVGSNSLLTYQLTEDSSFSLAMKVSKGGK 191

Query: 208 ---DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
              ++ L + LD E+  S+++V+ A DGG  ++S +  + +N+ D NDNAP F  + +  
Sbjct: 192 QQPELVLERALDREKQSSFQMVLTATDGGDSAKSGSVHIRVNVSDANDNAPVFNKNAYDA 251

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
            + EN+P+G  +++V+A DAD G N  ++Y     +   +V    +ID  SG V T+G L
Sbjct: 252 QMRENLPVGSLVLQVRAADADAGSNGRVSYFF--GNVPESVRSLFSIDAESGEVRTAGPL 309

Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
           D E ++KY   +   DGG                        +       + ED PPGT 
Sbjct: 310 DFEERSKYSFGLEGRDGGGLTGHCEVQIDIIDENDNAPEITTL--SLSSRVPEDAPPGTV 367

Query: 385 VVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
           V  L   D D  E+ ++  E++G        + S  G   +  A  LD ++   + +TV 
Sbjct: 368 VALLKVRDRDSGENGQVRCELSGDTPLQ--IVASSGGSYKVVTAGALDRERASEHRVTVI 425

Query: 443 ATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
           ATD G    S  A + + ++D N+ APVFE A Y+A V E+   G  VL VSA D+D G 
Sbjct: 426 ATDRGSPALSSRADLVLEVSDVNDNAPVFEEAAYSAYVPENNAAGEPVLRVSARDADAGA 485

Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560
           N +++Y+L+   ++ A         +  +TG +   +  D E    + + V ARDGG P+
Sbjct: 486 NGRVSYALAGGGADAAFVS------VRAETGELYAQRSFDYERCREFSVEVRARDGGTPA 539

Query: 561 LSDTTDVEISVVDVNDNEP-VFKQQLYTAN-----------IMEDALVGTSVSQVGATDA 608
            S T  V + V+D NDN P V       A            +   A  G  V++V A DA
Sbjct: 540 RSATATVRVFVLDRNDNAPRVLWPAAGGAEGGGAGAGPFEVVPRSAEAGYLVAKVVAVDA 599

Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
           D G N  + YEL  +  E   F ++  SG +RT +A   +    H L   A   G P  S
Sbjct: 600 DAGRNAWLSYEL-LQAPEPALFRVEARSGEVRTARA---KKQRPHPL---ATGHGQPALS 652

Query: 669 STVIVHIKI-EDINDSPP 685
           +T  +H+ + E + D+ P
Sbjct: 653 ATATLHVVLAESVRDALP 670



 Score =  192 bits (467), Expect = 2e-46
 Identities = 131/436 (30%), Positives = 216/436 (49%), Gaps = 21/436 (4%)

Query: 366 FMPGQYEVELAEDEPPGT--PVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL- 422
           F     ++E+ E   PG   P+      D   ++ L Y++T  ++       S+ G+   
Sbjct: 135 FSKAVLDLEIGEWTIPGARFPLEVAQDPDVGSNSLLTYQLTEDSSFSLAMKVSKGGKQQP 194

Query: 423 -ITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVF 479
            + + + LD +++  + + ++ATD G   +S +  +++N++DAN+ APVF    Y A + 
Sbjct: 195 ELVLERALDREKQSSFQMVLTATDGGDSAKSGSVHIRVNVSDANDNAPVFNKNAYDAQMR 254

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           E+ P+G+ VL V A D+D G N +++Y   +    E+V      F I+ ++G + T   L
Sbjct: 255 ENLPVGSLVLQVRAADADAGSNGRVSYFFGNV--PESVR---SLFSIDAESGEVRTAGPL 309

Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
           D E  S Y   +  RDGG   L+   +V+I ++D NDN P       ++ + EDA  GT 
Sbjct: 310 DFEERSKYSFGLEGRDGG--GLTGHCEVQIDIIDENDNAPEITTLSLSSRVPEDAPPGTV 367

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
           V+ +   D D G NG++  EL   D           S  + T  ALDRE  + H +  +A
Sbjct: 368 VALLKVRDRDSGENGQVRCELSG-DTPLQIVASSGGSYKVVTAGALDRERASEHRVTVIA 426

Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
            D G+P  SS   + +++ D+ND+ PVFE    + Y+ EN+  G  +  + A D D G N
Sbjct: 427 TDRGSPALSSRADLVLEVSDVNDNAPVFEEAAYSAYVPENNAAGEPVLRVSARDADAGAN 486

Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776
             V Y++ GG    +F +  R  ++  EL      DYE  R ++ + +RA    +P    
Sbjct: 487 GRVSYALAGGGADAAF-VSVR--AETGELYAQRSFDYERCR-EFSVEVRARDGGTPARSA 542

Query: 777 DVRVEILVTDVNDNAP 792
              V + V D NDNAP
Sbjct: 543 TATVRVFVLDRNDNAP 558



 Score =  181 bits (440), Expect = 3e-43
 Identities = 146/523 (27%), Positives = 234/523 (44%), Gaps = 53/523 (10%)

Query: 8   HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
           H ++ + D ND+SP F     +  + E    G       A D D+G N+ + Y +     
Sbjct: 120 HVEVAIHDINDNSPAFSKAVLDLEIGEWTIPGARFPLEVAQDPDVGSNSLLTYQLT---- 175

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
                ED+             V +   +   L+   +LDREK + + +++ ATD      
Sbjct: 176 -----EDSSFSLA------MKVSKGGKQQPELVLERALDREKQSSFQMVLTATDGGDSAK 224

Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
              S +  I VN+ D NDN P F++  Y   + E++ V    ++ +++A DAD G+N  +
Sbjct: 225 ---SGSVHIRVNVSDANDNAPVFNKNAYDAQMRENLPV--GSLVLQVRAADADAGSNGRV 279

Query: 188 RYAI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
            Y    +  + +  FSID+ SG+V     LD+E+   Y   +  +DGG    +   ++ I
Sbjct: 280 SYFFGNVPESVRSLFSIDAESGEVRTAGPLDFEERSKYSFGLEGRDGG--GLTGHCEVQI 337

Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
           +I D NDNAP   T      V E+ P G  +  ++  D D G N ++   ++        
Sbjct: 338 DIIDENDNAPEITTLSLSSRVPEDAPPGTVVALLKVRDRDSGENGQVRCELSG------- 390

Query: 306 DLPITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
           D P+ I   SG  Y   T+G LDRE  +++++ V ATD G P  S+ A            
Sbjct: 391 DTPLQIVASSGGSYKVVTAGALDRERASEHRVTVIATDRGSPALSSRADLVLEVSDVNDN 450

Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRF-SITSQNG 419
              F    Y   + E+   G PV+ ++A DAD   + R+ Y + GG     F S+ ++ G
Sbjct: 451 APVFEEAAYSAYVPENNAAGEPVLRVSARDADAGANGRVSYALAGGGADAAFVSVRAETG 510

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVF-------- 469
              +   +  D+++ R + + V A D G   RS TA V++ + D N+ AP          
Sbjct: 511 E--LYAQRSFDYERCREFSVEVRARDGGTPARSATATVRVFVLDRNDNAPRVLWPAAGGA 568

Query: 470 ENAPYTASVFEDAP----IGTTVLVVSATDSDVGINAQITYSL 508
           E     A  FE  P     G  V  V A D+D G NA ++Y L
Sbjct: 569 EGGGAGAGPFEVVPRSAEAGYLVAKVVAVDADAGRNAWLSYEL 611



 Score =  171 bits (417), Expect = 2e-40
 Identities = 113/348 (32%), Positives = 173/348 (49%), Gaps = 33/348 (9%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           +H ++NV D ND++PVF    Y+A +RE    G+ VL ++A D D G N  V Y    V 
Sbjct: 228 VHIRVNVSDANDNAPVFNKNAYDAQMRENLPVGSLVLQVRAADADAGSNGRVSYFFGNV- 286

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
                PE            V+ +F ID  SG + T   LD E+ ++Y+  ++  D     
Sbjct: 287 -----PE-----------SVRSLFSIDAESGEVRTAGPLDFEERSKYSFGLEGRDGGG-- 328

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
              L+    + ++IID+NDN P+ +  + +  V ED       V+A +K  D D G N  
Sbjct: 329 ---LTGHCEVQIDIIDENDNAPEITTLSLSSRVPED--APPGTVVALLKVRDRDSGENGQ 383

Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVK--TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
           +R   + G+T +Q  + S  G   +V    LD E+   +R+ + A D GSP+ S+   L+
Sbjct: 384 VR-CELSGDTPLQI-VASSGGSYKVVTAGALDRERASEHRVTVIATDRGSPALSSRADLV 441

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           + + DVNDNAP F  + +   V EN   G  ++RV A DAD G N  ++Y +      G 
Sbjct: 442 LEVSDVNDNAPVFEEAAYSAYVPENNAAGEPVLRVSARDADAGANGRVSYALAG----GG 497

Query: 305 VDLP-ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
            D   +++   +G +Y     D E   ++ + V A DGG P RSATAT
Sbjct: 498 ADAAFVSVRAETGELYAQRSFDYERCREFSVEVRARDGGTPARSATAT 545



 Score =  159 bits (385), Expect = 1e-36
 Identities = 121/422 (28%), Positives = 190/422 (45%), Gaps = 11/422 (2%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           V++ I D N+ +P F  A     + E    G    +  A D DVG N+ +TY L+ + S 
Sbjct: 121 VEVAIHDINDNSPAFSKAVLDLEIGEWTIPGARFPLEVAQDPDVGSNSLLTYQLTEDSSF 180

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
                  +     P+   +   + LDRE  S + + +TA DGG  + S +  + ++V D 
Sbjct: 181 SLAMKVSKGGKQQPE---LVLERALDREKQSSFQMVLTATDGGDSAKSGSVHIRVNVSDA 237

Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFVID 633
           NDN PVF +  Y A + E+  VG+ V QV A DAD G NGR+ Y   +  +     F ID
Sbjct: 238 NDNAPVFNKNAYDAQMRENLPVGSLVLQVRAADADAGSNGRVSYFFGNVPESVRSLFSID 297

Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693
             SG +RT   LD E  + +       DGG    +    V I I D ND+ P   +  L+
Sbjct: 298 AESGEVRTAGPLDFEERSKYSFGLEGRDGGG--LTGHCEVQIDIIDENDNAPEITTLSLS 355

Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753
             + E++P GT +  ++  D D G N  V   + G  D+    + +  GS K      +D
Sbjct: 356 SRVPEDAPPGTVVALLKVRDRDSGENGQVRCELSG--DTPLQIVASSGGSYKVVTAGALD 413

Query: 754 LDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF 813
            +  S  +   +     SP L +   + + V+DVNDNAPV ++        ++     P 
Sbjct: 414 RERASEHRVTVIATDRGSPALSSRADLVLEVSDVNDNAPVFEEAAYSAYVPENNAAGEPV 473

Query: 814 GRVPAYDAD--VTDKLQYRILSGN-NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVT 870
            RV A DAD     ++ Y +  G  +A  + +   TG +      +    +  ++EV   
Sbjct: 474 LRVSARDADAGANGRVSYALAGGGADAAFVSVRAETGELYAQRSFDYERCREFSVEVRAR 533

Query: 871 DG 872
           DG
Sbjct: 534 DG 535



 Score = 65.3 bits (152), Expect = 2e-08
 Identities = 65/242 (26%), Positives = 103/242 (42%), Gaps = 10/242 (4%)

Query: 601 SQVGATDADVGLN-GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK-AV 658
           S VG    D+GL+   +         E+  F +   +G +  ++ LDRE +       AV
Sbjct: 47  SLVGPLARDLGLSPAELPARQLRLSSEKLYFAVSGENGNLYVSERLDREELCRESESCAV 106

Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
           + +       +   V + I DIND+ P F    L   I E +  G       A DPD G 
Sbjct: 107 SFEAVVQNPLNVFHVEVAIHDINDNSPAFSKAVLDLEIGEWTIPGARFPLEVAQDPDVGS 166

Query: 719 NAVVHYSIKGGDDSNSFSLE-TRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPL 774
           N+++ Y +   D S S +++ ++ G  + ELV    LD E  +  +++V+ A        
Sbjct: 167 NSLLTYQLT-EDSSFSLAMKVSKGGKQQPELVLERALDREK-QSSFQMVLTATDGGDSAK 224

Query: 775 WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVTDKLQYRILS 833
              V + + V+D NDNAPV           ++  PVG    +V A DAD     +     
Sbjct: 225 SGSVHIRVNVSDANDNAPVFNK-NAYDAQMRENLPVGSLVLQVRAADADAGSNGRVSYFF 283

Query: 834 GN 835
           GN
Sbjct: 284 GN 285


>UniRef50_A4KCM6 Cluster: Protocadherin 2G25; n=4; Takifugu
           rubripes|Rep: Protocadherin 2G25 - Fugu rubripes
           (Japanese pufferfish) (Takifugu rubripes)
          Length = 950

 Score =  227 bits (555), Expect = 3e-57
 Identities = 154/510 (30%), Positives = 241/510 (47%), Gaps = 21/510 (4%)

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           + I D+NDN P F     +  +SE+   G   V  +A D D G+N+  +YT+   D    
Sbjct: 123 VEITDINDNPPTFERDEIRYDISESALTGARFVLEKAIDDDVGLNSLKSYTLKPSDNFVL 182

Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
             +      +   +    QLDRE Q    L++TA DGG+P  S T               
Sbjct: 183 KTVNRGDGSKHVEMVLQKQLDRENQNHVSLILTALDGGEPQLSGTMQIIVTVLDANDNPP 242

Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGL 422
                +Y+  + E+ P GT + T++ATD DE N   + Y I+     G F I + +G  +
Sbjct: 243 VCSKPEYKASVRENAPIGTRITTVSATDKDEGNNGIVTYMISKSGAAGLFRIDATDG--V 300

Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
           +T++  +D+++ + Y L V  +D GG SD   V +++TD N+  P       + +V E+ 
Sbjct: 301 LTLSGNVDYEKRKHYELDVQVSDQGGLSDACRVTVDVTDTNDNPPSINIMSKSQTVSENT 360

Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
             GT + +++  D D   N ++   L   I      H   +   N     IT ++L DRE
Sbjct: 361 KPGTVITMLNVQDPDSNENGRVMCVLDENI------HFTIRSTTNNFFTVITDSEL-DRE 413

Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
             S Y +TV+  D GVPSLS +  + + + DVNDN PVF++  Y A I+E+   G SV  
Sbjct: 414 RESEYNITVSCSDEGVPSLSSSVTLTLQISDVNDNPPVFERSSYEAYIVENNTPGLSVFT 473

Query: 603 VGATDADVGLNGRIHYELDPKDRE---EGSFV-IDPASGVIRTNKALDRESVATHDLKAV 658
           V A DAD   N R+ Y L+          S+V +   SGV+   ++ D E +        
Sbjct: 474 VKARDADWNQNARVSYILEDSSVNGVPVSSYVSVSADSGVVHAVRSFDYEQIKDFHFLVK 533

Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVF------ESDCLTFYISENSPIGTTIGEIRAH 712
           A DGG+PP SS V V I I+D ND+PP            +   +  ++ +G  + ++ A 
Sbjct: 534 AQDGGSPPLSSNVSVKILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAV 593

Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
           D D G NA + Y ++   D   F +  + G
Sbjct: 594 DVDSGQNAWLSYKLQKATDRALFEVGLQNG 623



 Score =  221 bits (541), Expect = 2e-55
 Identities = 174/597 (29%), Positives = 268/597 (44%), Gaps = 29/597 (4%)

Query: 97  GALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT 156
           G LL +  +DRE +   T+      Q   + +      T+ V I D NDN P F      
Sbjct: 84  GVLLIKDRIDREALCGQTMPCALHFQM--ILENPMEFYTVTVEITDINDNPPTFERDEIR 141

Query: 157 VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG----DVSLV 212
             + E  ++T    + + KA D DVG NS   Y +   +  +  +++   G    ++ L 
Sbjct: 142 YDISES-ALTGARFVLE-KAIDDDVGLNSLKSYTLKPSDNFVLKTVNRGDGSKHVEMVLQ 199

Query: 213 KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI 272
           K LD E      L++ A DGG P  S T Q+++ + D NDN P      ++ SV EN PI
Sbjct: 200 KQLDRENQNHVSLILTALDGGEPQLSGTMQIIVTVLDANDNPPVCSKPEYKASVRENAPI 259

Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332
           G  I  V A D DEG N  +TY ++     G       ID   G +  SG +D E +  Y
Sbjct: 260 GTRITTVSATDKDEGNNGIVTYMISKSGAAG----LFRIDATDGVLTLSGNVDYEKRKHY 315

Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392
           +L V  +D G    +   T               M     V  +E+  PGT +  L   D
Sbjct: 316 ELDVQVSDQGGLSDACRVTVDVTDTNDNPPSINIMSKSQTV--SENTKPGTVITMLNVQD 373

Query: 393 AD-EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GR 449
            D  +N     +   N       T+ N   +IT ++ LD ++E  Y +TVS +D G    
Sbjct: 374 PDSNENGRVMCVLDENIHFTIRSTTNNFFTVITDSE-LDRERESEYNITVSCSDEGVPSL 432

Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL- 508
           S +  + + I+D N+  PVFE + Y A + E+   G +V  V A D+D   NA+++Y L 
Sbjct: 433 SSSVTLTLQISDVNDNPPVFERSSYEAYIVENNTPGLSVFTVKARDADWNQNARVSYILE 492

Query: 509 SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568
            S ++   V+ +     ++  +G +   +  D E +  +   V A+DGG P LS    V+
Sbjct: 493 DSSVNGVPVSSY---VSVSADSGVVHAVRSFDYEQIKDFHFLVKAQDGGSPPLSSNVSVK 549

Query: 569 ISVVDVNDNEPVFKQQLYTANIM------EDALVGTSVSQVGATDADVGLNGRIHYELDP 622
           I + D NDN P     + T   M        A VG  V++V A D D G N  + Y+L  
Sbjct: 550 ILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLQ- 608

Query: 623 KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679
           K  +   F +   +G IRT + +  +      L  +  D G P +S+TVIV++ + D
Sbjct: 609 KATDRALFEVGLQNGEIRTIRQVTDKDAVKQRLSVIVEDNGQPSRSATVIVNVAVAD 665



 Score =  184 bits (449), Expect = 2e-44
 Identities = 157/578 (27%), Positives = 249/578 (43%), Gaps = 50/578 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + + D ND+ P FE  +    + E A +G   +  KA D D+G N+   Y        TL
Sbjct: 123 VEITDINDNPPTFERDEIRYDISESALTGARFVLEKAIDDDVGLNSLKSY--------TL 174

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            P D           ++ V R DG +   ++ +  LDRE     ++++ A D   P   +
Sbjct: 175 KPSD--------NFVLKTVNRGDGSKHVEMVLQKQLDRENQNHVSLILTALDGGEP---Q 223

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           LS T  I V ++D NDN P  S+  Y  SV E+  +     I  + ATD D G N  + Y
Sbjct: 224 LSGTMQIIVTVLDANDNPPVCSKPEYKASVRENAPIGTR--ITTVSATDKDEGNNGIVTY 281

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            I        F ID+  G ++L   +DYE+ + Y L ++  D G    S+  ++ +++ D
Sbjct: 282 MISKSGAAGLFRIDATDGVLTLSGNVDYEKRKHYELDVQVSDQG--GLSDACRVTVDVTD 339

Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            NDN P        ++VSEN   G  I  +   D D   N  +   + +     N+   I
Sbjct: 340 TNDNPPSINIMSKSQTVSENTKPGTVITMLNVQDPDSNENGRVMCVLDE-----NIHFTI 394

Query: 310 TIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
                + + V T  +LDRE +++Y + V+ +D G P  S++ T              F  
Sbjct: 395 RSTTNNFFTVITDSELDRERESEYNITVSCSDEGVPSLSSSVTLTLQISDVNDNPPVFER 454

Query: 369 GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRG---RFSITSQNGRGLI 423
             YE  + E+  PG  V T+ A DAD  ++ R+ Y +   +  G      ++     G++
Sbjct: 455 SSYEAYIVENNTPGLSVFTVKARDADWNQNARVSYILEDSSVNGVPVSSYVSVSADSGVV 514

Query: 424 TVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTAS---- 477
              +  D++Q + +   V A D G    S    V+I I D N+  P       T      
Sbjct: 515 HAVRSFDYEQIKDFHFLVKAQDGGSPPLSSNVSVKILIQDQNDNPPQVLYPVQTGGSMVA 574

Query: 478 --VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
             V   A +G  V  V A D D G NA ++Y L  + ++ A+      F +  Q G I T
Sbjct: 575 EMVPRSADVGYLVTKVVAVDVDSGQNAWLSYKL-QKATDRAL------FEVGLQNGEIRT 627

Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
            + +  +      L+V   D G PS S T  V ++V D
Sbjct: 628 IRQVTDKDAVKQRLSVIVEDNGQPSRSATVIVNVAVAD 665



 Score =  171 bits (416), Expect = 2e-40
 Identities = 122/379 (32%), Positives = 181/379 (47%), Gaps = 23/379 (6%)

Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFE 480
           + + + LD + +    L ++A D G    S T  + + + DAN+  PV     Y ASV E
Sbjct: 196 MVLQKQLDRENQNHVSLILTALDGGEPQLSGTMQIIVTVLDANDNPPVCSKPEYKASVRE 255

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           +APIGT +  VSATD D G N  +TY +S   S  A       F I+   G +T +  +D
Sbjct: 256 NAPIGTRITTVSATDKDEGNNGIVTYMISK--SGAAGL-----FRIDATDGVLTLSGNVD 308

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
            E    Y L V   D G   LSD   V + V D NDN P       +  + E+   GT +
Sbjct: 309 YEKRKHYELDVQVSDQG--GLSDACRVTVDVTDTNDNPPSINIMSKSQTVSENTKPGTVI 366

Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG---VIRTNKALDRESVATHDLKA 657
           + +   D D   NGR+   LD    E   F I   +     + T+  LDRE  + +++  
Sbjct: 367 TMLNVQDPDSNENGRVMCVLD----ENIHFTIRSTTNNFFTVITDSELDRERESEYNITV 422

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
              D G P  SS+V + ++I D+ND+PPVFE      YI EN+  G ++  ++A D D  
Sbjct: 423 SCSDEGVPSLSSSVTLTLQISDVNDNPPVFERSSYEAYIVENNTPGLSVFTVKARDADWN 482

Query: 718 PNAVVHYSIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPP 773
            NA V Y ++    +    S      +D   +  +   DYE   K +  +++A    SPP
Sbjct: 483 QNARVSYILEDSSVNGVPVSSYVSVSADSGVVHAVRSFDYEQI-KDFHFLVKAQDGGSPP 541

Query: 774 LWNDVRVEILVTDVNDNAP 792
           L ++V V+IL+ D NDN P
Sbjct: 542 LSSNVSVKILIQDQNDNPP 560



 Score =  165 bits (402), Expect = 1e-38
 Identities = 138/470 (29%), Positives = 205/470 (43%), Gaps = 43/470 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + VLD ND+ PV    +Y+ASVRE A  GT + T+ ATD+D G N  V Y I    A  L
Sbjct: 232 VTVLDANDNPPVCSKPEYKASVRENAPIGTRITTVSATDKDEGNNGIVTYMISKSGAAGL 291

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                              FRID   G L    ++D EK   Y + V+ +DQ       L
Sbjct: 292 -------------------FRIDATDGVLTLSGNVDYEKRKHYELDVQVSDQGG-----L 327

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           S    + V++ D NDN P  +  + + +V E  +     VI  +   D D   N  +   
Sbjct: 328 SDACRVTVDVTDTNDNPPSINIMSKSQTVSE--NTKPGTVITMLNVQDPDSNENGRVMCV 385

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
           +   +  + F+I S + +   V T   LD E+   Y + +   D G PS S++  L + I
Sbjct: 386 L---DENIHFTIRSTTNNFFTVITDSELDRERESEYNITVSCSDEGVPSLSSSVTLTLQI 442

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NVD 306
            DVNDN P F  S ++  + EN   G S+  V+A DAD   NA ++Y + D    G  V 
Sbjct: 443 SDVNDNPPVFERSSYEAYIVENNTPGLSVFTVKARDADWNQNARVSYILEDSSVNGVPVS 502

Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
             +++   SG V+     D E    +  LV A DGG PP S+  +               
Sbjct: 503 SYVSVSADSGVVHAVRSFDYEQIKDFHFLVKAQDGGSPPLSSNVSVKILIQDQNDNPPQV 562

Query: 367 M-PGQYEVELAEDEPP-----GTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQN 418
           + P Q    +  +  P     G  V  + A D D      L Y++     R  F +  QN
Sbjct: 563 LYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLQKATDRALFEVGLQN 622

Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468
           G  + T+ Q  D K   +  L+V   D+G  S +A V +N+  A+++  V
Sbjct: 623 GE-IRTIRQVTD-KDAVKQRLSVIVEDNGQPSRSATVIVNVAVADSFPEV 670



 Score =  150 bits (364), Expect = 5e-34
 Identities = 106/346 (30%), Positives = 166/346 (47%), Gaps = 18/346 (5%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL--SSEI 512
           V + ITD N+  P FE       + E A  G   ++  A D DVG+N+  +Y+L  S   
Sbjct: 121 VTVEITDINDNPPTFERDEIRYDISESALTGARFVLEKAIDDDVGLNSLKSYTLKPSDNF 180

Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572
             + V   D    +      +   K LDRE  +   L +TA DGG P LS T  + ++V+
Sbjct: 181 VLKTVNRGDGSKHVE-----MVLQKQLDRENQNHVSLILTALDGGEPQLSGTMQIIVTVL 235

Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632
           D NDN PV  +  Y A++ E+A +GT ++ V ATD D G NG + Y +  K    G F I
Sbjct: 236 DANDNPPVCSKPEYKASVRENAPIGTRITTVSATDKDEGNNGIVTYMIS-KSGAAGLFRI 294

Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692
           D   GV+  +  +D E    ++L     D G    S    V + + D ND+PP       
Sbjct: 295 DATDGVLTLSGNVDYEKRKHYELDVQVSDQGG--LSDACRVTVDVTDTNDNPPSINIMSK 352

Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752
           +  +SEN+  GT I  +   DPD   N  V   +   D++  F++ +   ++   ++T  
Sbjct: 353 SQTVSENTKPGTVITMLNVQDPDSNENGRVMCVL---DENIHFTIRSTT-NNFFTVITDS 408

Query: 753 DLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMK 795
           +LD E    +Y + +  +    P L + V + + ++DVNDN PV +
Sbjct: 409 ELDRER-ESEYNITVSCSDEGVPSLSSSVTLTLQISDVNDNPPVFE 453



 Score = 78.6 bits (185), Expect = 2e-12
 Identities = 60/205 (29%), Positives = 99/205 (48%), Gaps = 8/205 (3%)

Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732
           V ++I DIND+PP FE D + + ISE++  G      +A D D G N++  Y++K  D+ 
Sbjct: 121 VTVEITDINDNPPTFERDEIRYDISESALTGARFVLEKAIDDDVGLNSLKSYTLKPSDNF 180

Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVND 789
              ++    GS   E+V    LD E+ +    L++ A     P L   +++ + V D ND
Sbjct: 181 VLKTVNRGDGSKHVEMVLQKQLDREN-QNHVSLILTALDGGEPQLSGTMQIIVTVLDAND 239

Query: 790 NAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADVTDK--LQYRILSGNNANLILLNETT 846
           N PV    +    + ++  P+G     V A D D  +   + Y I     A L  ++ T 
Sbjct: 240 NPPVCSKPE-YKASVRENAPIGTRITTVSATDKDEGNNGIVTYMISKSGAAGLFRIDATD 298

Query: 847 GSMTLSPQLNTNVPKLATMEVSVTD 871
           G +TLS  ++    K   ++V V+D
Sbjct: 299 GVLTLSGNVDYEKRKHYELDVQVSD 323


>UniRef50_UPI0000F1FBA8 Cluster: PREDICTED: hypothetical protein;
           n=2; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 841

 Score =  226 bits (553), Expect = 6e-57
 Identities = 194/715 (27%), Positives = 321/715 (44%), Gaps = 31/715 (4%)

Query: 91  RIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQF 150
           R+D  +G L T+  LDRE +       + T   + V         + + + D NDN P F
Sbjct: 65  RVDEITGDLFTKDRLDRETLCPSHQDGECTFLNTAVVSPHLDVVPMVIVVNDINDNAPVF 124

Query: 151 SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVS 210
                 + + ED S+     +   +A D D   N  I Y + G N       +    ++ 
Sbjct: 125 ERNEIPLRIPEDTSI-GTTFLLDDQAQDKDTANNGLIHYHLEGSNGFFGIRQEDYGLELI 183

Query: 211 LVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENV 270
           + K LD E   +Y LV+ A D GS   S T  L + + DV+DN P F      +++   +
Sbjct: 184 VQKELDRETQDNYFLVLVAVDRGSMPLSATANLSVTVTDVDDNCPEFDDDSPIKAIVPGL 243

Query: 271 PI-GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329
            I G ++ +++A D D G NA++T++ + +  +        +D  +G +  +  +  ++ 
Sbjct: 244 GIKGTAVAQLKATDKDLGQNAQITFSFS-RQISDRAKTLFYMDRHTGLISLAVDVHTDSP 302

Query: 330 AKYQLLVTATDGGDPPRSATATXXX--XXXXXXXXXXXFMPGQYE--VELAEDEPPGTPV 385
            ++ L V A     PP  A  T                F+       + L E+EPP T +
Sbjct: 303 EEHMLKVFANGPLCPPAQAQVTVYIQPMVSSEPTIKIRFVTEHKNQVIMLQENEPP-TVL 361

Query: 386 VTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445
             L   D   D      ++       FS+  Q G  L++ ++ LDF+    Y +TV  +D
Sbjct: 362 ALLELEDTSSDKG---TLSLETDSMPFSLKQQAGSYLLSTSKALDFELCGEYDVTVVISD 418

Query: 446 SGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503
             G       ++++ + D N+ AP FE   Y   + E+   G  +L V ATD+D     +
Sbjct: 419 PHGARLHGREVIKVVVQDLNDNAPKFEQTRYETDIKENNKPGEFLLKVQATDADSHQFGK 478

Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD 563
           + Y ++          +   F I  +TG I   + LDRE    Y+LTV A+DGG PS   
Sbjct: 479 VEYRIT----------NGSPFRIQEETGVILVTEPLDREQQGTYILTVLAQDGGDPSQEA 528

Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK 623
              V ++V+D+NDN P F    +   + E     + V +V  +DAD G NGRI   +D +
Sbjct: 529 FAIVFVNVLDMNDNPPAFPTPHFYFFVSESLPHLSQVGKVTVSDADDGDNGRI---VDLR 585

Query: 624 D-REEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND 682
              ++  FVID + G++R+   +DRE    ++L  VA+DGG+P  S+TV + + +EDIND
Sbjct: 586 ILNDKAPFVIDMSQGMLRSTGEVDREKQDRYELLVVAVDGGSPVLSTTVKMTVFVEDIND 645

Query: 683 SPP---VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLET 739
           + P   +  S+     IS  +  G+ I +I A D D G N+ + Y I   + +     + 
Sbjct: 646 NQPQVLLPSSNLSCLTISPATQAGSMITKIYAIDEDSGMNSDITYQIIASEPALQSPFQI 705

Query: 740 RQGSDKAELVTMVDLDYESPRKKYELVIRAASP-PLWNDVRVEILVTDVNDNAPV 793
            Q S    LV  +  +       + +V     P PL   + V +LV +  +   V
Sbjct: 706 DQHSGNITLVQHLRGEDYGMHHLFIVVRDGGKPDPLQTTIWVNLLVNETLEKCHV 760



 Score =  189 bits (461), Expect = 8e-46
 Identities = 183/687 (26%), Positives = 304/687 (44%), Gaps = 63/687 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTT-VLTLKATDQDIGKNAEVEYTIELVTADT 69
           I V D ND++PVFE  +    + E  S GTT +L  +A D+D   N  + Y +E      
Sbjct: 112 IVVNDINDNAPVFERNEIPLRIPEDTSIGTTFLLDDQAQDKDTANNGLIHYHLE------ 165

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                            Q+ + ++     L+ +  LDRE    Y +++ A D+ S     
Sbjct: 166 --------GSNGFFGIRQEDYGLE-----LIVQKELDRETQDNYFLVLVAVDRGSM---P 209

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           LS+TA + V + D +DN P+F + +   ++   + +     +A++KATD D+G N+ I +
Sbjct: 210 LSATANLSVTVTDVDDNCPEFDDDSPIKAIVPGLGI-KGTAVAQLKATDKDLGQNAQITF 268

Query: 190 AI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           +    I    +  F +D  +G +SL   +  +    + L + A     P      Q+ + 
Sbjct: 269 SFSRQISDRAKTLFYMDRHTGLISLAVDVHTDSPEEHMLKVFANGPLCPPAQ--AQVTVY 326

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN-AELTYTMTDKDYTG-- 303
           I+ +  + P        E  ++       ++ +Q  +    +   EL  T +DK      
Sbjct: 327 IQPMVSSEPTIKIRFVTEHKNQ-------VIMLQENEPPTVLALLELEDTSSDKGTLSLE 379

Query: 304 NVDLPITIDPRSG--WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
              +P ++  ++G   + TS  LD E   +Y + V  +D                     
Sbjct: 380 TDSMPFSLKQQAGSYLLSTSKALDFELCGEYDVTVVISDPHGARLHGREVIKVVVQDLND 439

Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419
               F   +YE ++ E+  PG  ++ + ATDAD  +  ++ Y IT G+    F I  Q  
Sbjct: 440 NAPKFEQTRYETDIKENNKPGEFLLKVQATDADSHQFGKVEYRITNGSP---FRI--QEE 494

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDT--AMVQINITDANNYAPVFENAPYTAS 477
            G+I V +PLD +Q+  Y+LTV A D G  S    A+V +N+ D N+  P F    +   
Sbjct: 495 TGVILVTEPLDREQQGTYILTVLAQDGGDPSQEAFAIVFVNVLDMNDNPPAFPTPHFYFF 554

Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
           V E  P  + V  V+ +D+D G N +I   +   I N+        FVI+   G + +  
Sbjct: 555 VSESLPHLSQVGKVTVSDADDGDNGRI---VDLRILNDKA-----PFVIDMSQGMLRSTG 606

Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP---VFKQQLYTANIMEDA 594
            +DRE    Y L V A DGG P LS T  + + V D+NDN+P   +    L    I    
Sbjct: 607 EVDREKQDRYELLVVAVDGGSPVLSTTVKMTVFVEDINDNQPQVLLPSSNLSCLTISPAT 666

Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNKALDRESVATH 653
             G+ ++++ A D D G+N  I Y++   +   +  F ID  SG I   + L  E    H
Sbjct: 667 QAGSMITKIYAIDEDSGMNSDITYQIIASEPALQSPFQIDQHSGNITLVQHLRGEDYGMH 726

Query: 654 DLKAVAIDGGTP-PQSSTVIVHIKIED 679
            L  V  DGG P P  +T+ V++ + +
Sbjct: 727 HLFIVVRDGGKPDPLQTTIWVNLLVNE 753



 Score =  168 bits (409), Expect = 2e-39
 Identities = 170/672 (25%), Positives = 293/672 (43%), Gaps = 48/672 (7%)

Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYS-IVRVQAYDADEGVNAELTYTMTDKDY 301
           ++I + D+NDNAP F  +     + E+  IG + ++  QA D D   N  + Y +     
Sbjct: 110 MVIVVNDINDNAPVFERNEIPLRIPEDTSIGTTFLLDDQAQDKDTANNGLIHYHLEGS-- 167

Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
             N    I  +     +    +LDRETQ  Y L++ A D G  P SATA           
Sbjct: 168 --NGFFGIRQEDYGLELIVQKELDRETQDNYFLVLVAVDRGSMPLSATANLSVTVTDVDD 225

Query: 362 XXXXFMPGQYEVELAEDEP-PGTPVVTLTATDAD--EDNRLHYEITGG-NTRGRFSITSQ 417
               F        +       GT V  L ATD D  ++ ++ +  +   + R +      
Sbjct: 226 NCPEFDDDSPIKAIVPGLGIKGTAVAQLKATDKDLGQNAQITFSFSRQISDRAKTLFYMD 285

Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTAS 477
              GLI++A  +       ++L V A  +G     A  Q+ +       P+  + P T  
Sbjct: 286 RHTGLISLAVDVHTDSPEEHMLKVFA--NGPLCPPAQAQVTVY----IQPMVSSEP-TIK 338

Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA--ITT 535
           +         V+++   +    +        SS+    ++      F +  Q G+  ++T
Sbjct: 339 IRFVTEHKNQVIMLQENEPPTVLALLELEDTSSDKGTLSLETDSMPFSLKQQAGSYLLST 398

Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
           +K LD E    Y +TV   D     L     +++ V D+NDN P F+Q  Y  +I E+  
Sbjct: 399 SKALDFELCGEYDVTVVISDPHGARLHGREVIKVVVQDLNDNAPKFEQTRYETDIKENNK 458

Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKALDRESVATHD 654
            G  + +V ATDAD    G++ Y +       GS F I   +GVI   + LDRE   T+ 
Sbjct: 459 PGEFLLKVQATDADSHQFGKVEYRIT-----NGSPFRIQEETGVILVTEPLDREQQGTYI 513

Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
           L  +A DGG P Q +  IV + + D+ND+PP F +    F++SE+ P  + +G++   D 
Sbjct: 514 LTVLAQDGGDPSQEAFAIVFVNVLDMNDNPPAFPTPHFYFFVSESLPHLSQVGKVTVSDA 573

Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---AS 771
           D+G N  +   ++  +D   F ++  QG     L +  ++D E  + +YEL++ A    S
Sbjct: 574 DDGDNGRI-VDLRILNDKAPFVIDMSQGM----LRSTGEVDREK-QDRYELLVVAVDGGS 627

Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-------FGRVPAYDAD-- 822
           P L   V++ + V D+NDN P +    ++ ++   C  + P         ++ A D D  
Sbjct: 628 PVLSTTVKMTVFVEDINDNQPQV----LLPSSNLSCLTISPATQAGSMITKIYAIDEDSG 683

Query: 823 VTDKLQYRILSGNNA--NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMM 880
           +   + Y+I++   A  +   +++ +G++TL   L      +  + + V DG        
Sbjct: 684 MNSDITYQIIASEPALQSPFQIDQHSGNITLVQHLRGEDYGMHHLFIVVRDGGKPDPLQT 743

Query: 881 QLSVRLITEEML 892
            + V L+  E L
Sbjct: 744 TIWVNLLVNETL 755



 Score =  132 bits (318), Expect = 2e-28
 Identities = 100/338 (29%), Positives = 155/338 (45%), Gaps = 33/338 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ V D ND++P FE  +YE  ++E    G  +L ++ATD D  +  +VEY I       
Sbjct: 431 KVVVQDLNDNAPKFEQTRYETDIKENNKPGEFLLKVQATDADSHQFGKVEYRI-----TN 485

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            +P                 FRI   +G +L    LDRE+   Y + V A D   P  + 
Sbjct: 486 GSP-----------------FRIQEETGVILVTEPLDREQQGTYILTVLAQDGGDPSQE- 527

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             + A + VN++D NDN P F    +   V E  S+     + K+  +DAD G N  I  
Sbjct: 528 --AFAIVFVNVLDMNDNPPAFPTPHFYFFVSE--SLPHLSQVGKVTVSDADDGDNGRIVD 583

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             I  N +  F ID   G +     +D E+   Y L++ A DGGSP  S T ++ + + D
Sbjct: 584 LRI-LNDKAPFVIDMSQGMLRSTGEVDREKQDRYELLVVAVDGGSPVLSTTVKMTVFVED 642

Query: 250 VNDNAPRFY---TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
           +NDN P+     ++L   ++S     G  I ++ A D D G+N+++TY +   +    + 
Sbjct: 643 INDNQPQVLLPSSNLSCLTISPATQAGSMITKIYAIDEDSGMNSDITYQIIASEPA--LQ 700

Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP 344
            P  ID  SG +     L  E    + L +   DGG P
Sbjct: 701 SPFQIDQHSGNITLVQHLRGEDYGMHHLFIVVRDGGKP 738



 Score = 77.8 bits (183), Expect = 4e-12
 Identities = 78/286 (27%), Positives = 133/286 (46%), Gaps = 21/286 (7%)

Query: 632 IDPASGVIRTNKALDRESVA-TH-DLKAVAIDGGT-PPQSSTVIVHIKIEDINDSPPVFE 688
           +D  +G + T   LDRE++  +H D +   ++     P    V + I + DIND+ PVFE
Sbjct: 66  VDEITGDLFTKDRLDRETLCPSHQDGECTFLNTAVVSPHLDVVPMVIVVNDINDNAPVFE 125

Query: 689 SDCLTFYISENSPIGTT-IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747
            + +   I E++ IGTT + + +A D D   N ++HY ++G   SN F    RQ     E
Sbjct: 126 RNEIPLRIPEDTSIGTTFLLDDQAQDKDTANNGLIHYHLEG---SNGF-FGIRQEDYGLE 181

Query: 748 LVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY 804
           L+   +LD E+ +  Y LV+ A    S PL     + + VTDV+DN P   D   I    
Sbjct: 182 LIVQKELDRET-QDNYFLVLVAVDRGSMPLSATANLSVTVTDVDDNCPEFDDDSPIKAIV 240

Query: 805 KDCFPVG-PFGRVPAYDADVTDKLQY-----RILSGNNANLILLNETTGSMTLSPQLNTN 858
                 G    ++ A D D+    Q      R +S     L  ++  TG ++L+  ++T+
Sbjct: 241 PGLGIKGTAVAQLKATDKDLGQNAQITFSFSRQISDRAKTLFYMDRHTGLISLAVDVHTD 300

Query: 859 VPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMT 904
            P+   ++V        +    Q  V +  + M+ +  T+++  +T
Sbjct: 301 SPEEHMLKVFAN---GPLCPPAQAQVTVYIQPMVSSEPTIKIRFVT 343


>UniRef50_A1L1W7 Cluster: LOC555688 protein; n=6; Euteleostomi|Rep:
           LOC555688 protein - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 1078

 Score =  226 bits (552), Expect = 8e-57
 Identities = 164/506 (32%), Positives = 239/506 (47%), Gaps = 32/506 (6%)

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           I I DVNDNAPRF T+     +SEN   G       A D D G N   TYT+T  D  G 
Sbjct: 108 IEIIDVNDNAPRFPTNHIDIEISENAAPGTRFPLEGASDPDSGSNGIQTYTITPNDIFG- 166

Query: 305 VDLPITID-PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
           +++    D  +   +     LDRETQ++Y   +TA DGGDPP+S T              
Sbjct: 167 LEIKTRGDGSKIAELVVEKTLDRETQSRYTFELTAEDGGDPPKSGTVQLNIKVIDSNDNN 226

Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI---TGGNTRGRFSITSQN 418
             F    Y V + E+ P  T V+ L ATD DE  +  + Y         T+  F I  + 
Sbjct: 227 PVFDEPVYTVNVLENSPINTLVIDLNATDPDEGTNGEVVYSFINFVSNLTKQMFKIDPKT 286

Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAP----VFENA 472
           G  +ITV   LD ++   + + V A D G  S  A   V +N+ D N+ AP    + EN+
Sbjct: 287 G--VITVNGVLDHEELHIHEIDVQAKDLGPNSIPAHCKVIVNVIDINDNAPEIKLLSENS 344

Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
                V E+AP+G  + +V  +D+D G N ++   L   +      +  + F        
Sbjct: 345 EMV-EVSENAPLGYVIALVRVSDNDSGANGKVQCRLQGNVPFRL--NEFESF------ST 395

Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592
           +  +  LDRE    Y LT+ A D G P L  +    + V D NDN P F +  Y A ++E
Sbjct: 396 LLVDGRLDREQRDMYNLTILAEDSGYPPLRSSKSFAVKVTDENDNPPYFTKPHYQAMVLE 455

Query: 593 DALVGTSVSQVGATDADVGLNGRIHYEL---DPKDREEGSFVIDPASGVIRTNKALDRES 649
           + + G  +  V A D D+G+NG + YE+   + +     S+V   ++G I   +A + E 
Sbjct: 456 NNVPGAFLLAVSARDPDLGMNGTVSYEIIKSEVRGMSVESYVTVNSNGEIYGVRAFNHED 515

Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT-----FYISENSPIGT 704
             T + K  A DGG PP +S   V I + D+ND+ PV  +  L        I +N+ +G 
Sbjct: 516 TRTFEFKVSAKDGGDPPLTSNATVRIVVLDVNDNTPVMTTPPLVNGTAEVSIPKNAGVGY 575

Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGD 730
            + +I+A D DEG N  + YSI  GD
Sbjct: 576 LVTQIKADDYDEGENGRLTYSISEGD 601



 Score =  213 bits (520), Expect = 6e-53
 Identities = 173/600 (28%), Positives = 271/600 (45%), Gaps = 58/600 (9%)

Query: 2   SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
           S+  C+ + I ++D ND++P F     +  + E A+ GT      A+D D G N    YT
Sbjct: 100 SMEICVIK-IEIIDVNDNAPRFPTNHIDIEISENAAPGTRFPLEGASDPDSGSNGIQTYT 158

Query: 62  IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKAT 120
           I         P D           ++   R DG +   L+   +LDRE  +RYT  + A 
Sbjct: 159 I--------TPND--------IFGLEIKTRGDGSKIAELVVEKTLDRETQSRYTFELTAE 202

Query: 121 DQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD 180
           D   P     S T  +++ +ID NDN P F E  YTV+V E+  +  N ++  + ATD D
Sbjct: 203 DGGDPPK---SGTVQLNIKVIDSNDNNPVFDEPVYTVNVLENSPI--NTLVIDLNATDPD 257

Query: 181 VGANSAIRYAII---GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237
            G N  + Y+ I      T+  F ID  +G +++   LD+E++  + + ++A+D G  S 
Sbjct: 258 EGTNGEVVYSFINFVSNLTKQMFKIDPKTGVITVNGVLDHEELHIHEIDVQAKDLGPNSI 317

Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQES-----VSENVPIGYSIVRVQAYDADEGVNAEL 292
               ++++N+ D+NDNAP     L  E+     VSEN P+GY I  V+  D D G N ++
Sbjct: 318 PAHCKVIVNVIDINDNAPEI--KLLSENSEMVEVSENAPLGYVIALVRVSDNDSGANGKV 375

Query: 293 TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352
              +      GNV   +        +   G+LDRE +  Y L + A D G PP  ++ + 
Sbjct: 376 QCRL-----QGNVPFRLNEFESFSTLLVDGRLDREQRDMYNLTILAEDSGYPPLRSSKSF 430

Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRG 410
                        F    Y+  + E+  PG  ++ ++A D D   +  + YEI     RG
Sbjct: 431 AVKVTDENDNPPYFTKPHYQAMVLENNVPGAFLLAVSARDPDLGMNGTVSYEIIKSEVRG 490

Query: 411 RF--SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYA 466
               S  + N  G I   +  + +  R +   VSA D G    +  A V+I + D N+  
Sbjct: 491 MSVESYVTVNSNGEIYGVRAFNHEDTRTFEFKVSAKDGGDPPLTSNATVRIVVLDVNDNT 550

Query: 467 PVFENAPYT-----ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521
           PV    P        S+ ++A +G  V  + A D D G N ++TYS    IS   +A+  
Sbjct: 551 PVMTTPPLVNGTAEVSIPKNAGVGYLVTQIKADDYDEGENGRLTYS----ISEGDMAY-- 604

Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV-VDVNDNEPV 580
             F I+   G + T K         Y +TV A D G  SLS +  + I +  D+N  E +
Sbjct: 605 --FEIDQINGEVRTTKTFGENAKPSYQITVVAHDHGQTSLSASAYIVIYLSPDLNAQEQI 662



 Score =  212 bits (517), Expect = 1e-52
 Identities = 176/606 (29%), Positives = 273/606 (45%), Gaps = 37/606 (6%)

Query: 96  SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155
           +G L+T+  +DR+ V R T   K       +S+ +     I + IID NDN P+F     
Sbjct: 69  AGLLITKQKIDRDAVCRQTP--KCFISLEVMSNSME-ICVIKIEIIDVNDNAPRFPTNHI 125

Query: 156 TVSVDEDISV-TDNPVIAKIKATDADVGANSAIRYAIIGGNT---QMQFSID-SLSGDVS 210
            + + E+ +  T  P+     A+D D G+N    Y I   +    +++   D S   ++ 
Sbjct: 126 DIEISENAAPGTRFPLEG---ASDPDSGSNGIQTYTITPNDIFGLEIKTRGDGSKIAELV 182

Query: 211 LVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENV 270
           + KTLD E    Y   + A+DGG P +S T QL I + D NDN P F   ++  +V EN 
Sbjct: 183 VEKTLDRETQSRYTFELTAEDGGDPPKSGTVQLNIKVIDSNDNNPVFDEPVYTVNVLENS 242

Query: 271 PIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI-TIDPRSGWVYTSGQLDRETQ 329
           PI   ++ + A D DEG N E+ Y+    ++  N+   +  IDP++G +  +G LD E  
Sbjct: 243 PINTLVIDLNATDPDEGTNGEVVYSFI--NFVSNLTKQMFKIDPKTGVITVNGVLDHEEL 300

Query: 330 AKYQLLVTATDGGD---PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386
             +++ V A D G    P                            VE++E+ P G  + 
Sbjct: 301 HIHEIDVQAKDLGPNSIPAHCKVIVNVIDINDNAPEIKLLSENSEMVEVSENAPLGYVIA 360

Query: 387 TLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444
            +  +D D   + ++   + G      F +        + V   LD +Q   Y LT+ A 
Sbjct: 361 LVRVSDNDSGANGKVQCRLQGNVP---FRLNEFESFSTLLVDGRLDREQRDMYNLTILAE 417

Query: 445 DSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501
           DSG    RS  +   + +TD N+  P F    Y A V E+   G  +L VSA D D+G+N
Sbjct: 418 DSGYPPLRSSKSFA-VKVTDENDNPPYFTKPHYQAMVLENNVPGAFLLAVSARDPDLGMN 476

Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL 561
             ++Y +   I +E      + +V     G I   +  + E    +   V+A+DGG P L
Sbjct: 477 GTVSYEI---IKSEVRGMSVESYVTVNSNGEIYGVRAFNHEDTRTFEFKVSAKDGGDPPL 533

Query: 562 SDTTDVEISVVDVNDNEPVFK-----QQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616
           +    V I V+DVNDN PV             +I ++A VG  V+Q+ A D D G NGR+
Sbjct: 534 TSNATVRIVVLDVNDNTPVMTTPPLVNGTAEVSIPKNAGVGYLVTQIKADDYDEGENGRL 593

Query: 617 HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID-GGTPPQSSTVIVHI 675
            Y +   D     F ID  +G +RT K     +  ++ +  VA D G T   +S  IV  
Sbjct: 594 TYSISEGDM--AYFEIDQINGEVRTTKTFGENAKPSYQITVVAHDHGQTSLSASAYIVIY 651

Query: 676 KIEDIN 681
              D+N
Sbjct: 652 LSPDLN 657



 Score =  192 bits (469), Expect = 9e-47
 Identities = 137/443 (30%), Positives = 217/443 (48%), Gaps = 23/443 (5%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADE-DNRLH-YEITGGNTRGRFSITSQNGRGL- 422
           F     ++E++E+  PGT      A+D D   N +  Y IT  +  G    T  +G  + 
Sbjct: 120 FPTNHIDIEISENAAPGTRFPLEGASDPDSGSNGIQTYTITPNDIFGLEIKTRGDGSKIA 179

Query: 423 -ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVF 479
            + V + LD + + RY   ++A D G   +S T  + I + D+N+  PVF+   YT +V 
Sbjct: 180 ELVVEKTLDRETQSRYTFELTAEDGGDPPKSGTVQLNIKVIDSNDNNPVFDEPVYTVNVL 239

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           E++PI T V+ ++ATD D G N ++ YS  + +SN       Q F I+P+TG IT N +L
Sbjct: 240 ENSPINTLVIDLNATDPDEGTNGEVVYSFINFVSNLT----KQMFKIDPKTGVITVNGVL 295

Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK---QQLYTANIMEDALV 596
           D E +  + + V A+D G  S+     V ++V+D+NDN P  K   +      + E+A +
Sbjct: 296 DHEELHIHEIDVQAKDLGPNSIPAHCKVIVNVIDINDNAPEIKLLSENSEMVEVSENAPL 355

Query: 597 GTSVSQVGATDADVGLNGRIHYELDPK-DREEGSFVIDPASGVIRTNKALDRESVATHDL 655
           G  ++ V  +D D G NG++   L          F    +   +  +  LDRE    ++L
Sbjct: 356 GYVIALVRVSDNDSGANGKVQCRLQGNVPFRLNEF---ESFSTLLVDGRLDREQRDMYNL 412

Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
             +A D G PP  S+    +K+ D ND+PP F        + EN+  G  +  + A DPD
Sbjct: 413 TILAEDSGYPPLRSSKSFAVKVTDENDNPPYFTKPHYQAMVLENNVPGAFLLAVSARDPD 472

Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQG-SDKAELVTMVDLDYESPRKKYELVIRA---AS 771
            G N  V Y I   +     S+E+    +   E+  +   ++E  R  +E  + A     
Sbjct: 473 LGMNGTVSYEIIKSE-VRGMSVESYVTVNSNGEIYGVRAFNHEDTRT-FEFKVSAKDGGD 530

Query: 772 PPLWNDVRVEILVTDVNDNAPVM 794
           PPL ++  V I+V DVNDN PVM
Sbjct: 531 PPLTSNATVRIVVLDVNDNTPVM 553



 Score =  165 bits (400), Expect = 2e-38
 Identities = 140/482 (29%), Positives = 209/482 (43%), Gaps = 35/482 (7%)

Query: 370 QYEVELAEDEPPGTPVVTLTATDADE-----DNRLHYEITGGNTRGRFSITSQNGRGLIT 424
           +Y VE  E+   GT +  +TA DA        NR  Y     N+  R+   + +  GL+ 
Sbjct: 19  KYTVE--EELRAGTKIANVTA-DAKVAGFALGNRQPYLRVISNSEPRW--VNLSPAGLLI 73

Query: 425 VAQPLDFKQERRYV--LTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
             Q +D     R      +S        +  +++I I D N+ AP F        + E+A
Sbjct: 74  TKQKIDRDAVCRQTPKCFISLEVMSNSMEICVIKIEIIDVNDNAPRFPTNHIDIEISENA 133

Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
             GT   +  A+D D G N   TY+++    N+      +      +   +   K LDRE
Sbjct: 134 APGTRFPLEGASDPDSGSNGIQTYTITP---NDIFGLEIKTRGDGSKIAELVVEKTLDRE 190

Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
           T S Y   +TA DGG P  S T  + I V+D NDN PVF + +YT N++E++ + T V  
Sbjct: 191 TQSRYTFELTAEDGGDPPKSGTVQLNIKVIDSNDNNPVFDEPVYTVNVLENSPINTLVID 250

Query: 603 VGATDADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
           + ATD D G NG + Y       +  +  F IDP +GVI  N  LD E +  H++   A 
Sbjct: 251 LNATDPDEGTNGEVVYSFINFVSNLTKQMFKIDPKTGVITVNGVLDHEELHIHEIDVQAK 310

Query: 661 DGGTPPQSSTVIVHIKIEDINDSPP---VFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
           D G     +   V + + DIND+ P   +   +     +SEN+P+G  I  +R  D D G
Sbjct: 311 DLGPNSIPAHCKVIVNVIDINDNAPEIKLLSENSEMVEVSENAPLGYVIALVRVSDNDSG 370

Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPL 774
            N  V   ++G     +      +    + L+    LD E  R  Y L I A     PPL
Sbjct: 371 ANGKVQCRLQG-----NVPFRLNEFESFSTLLVDGRLDREQ-RDMYNLTILAEDSGYPPL 424

Query: 775 WNDVRVEILVTDVNDNAPVMK----DFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYR 830
            +     + VTD NDN P          ++ NN    F +    R P  D  +   + Y 
Sbjct: 425 RSSKSFAVKVTDENDNPPYFTKPHYQAMVLENNVPGAFLLAVSARDP--DLGMNGTVSYE 482

Query: 831 IL 832
           I+
Sbjct: 483 II 484



 Score =  155 bits (376), Expect = 2e-35
 Identities = 136/499 (27%), Positives = 223/499 (44%), Gaps = 37/499 (7%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           +   I V+D ND++PVF+   Y  +V E +   T V+ L ATD D G N EV Y+     
Sbjct: 213 VQLNIKVIDSNDNNPVFDEPVYTVNVLENSPINTLVIDLNATDPDEGTNGEVVYSF---- 268

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
              +N               + +F+ID ++G +     LD E++  + + V+A D   P 
Sbjct: 269 ---IN---------FVSNLTKQMFKIDPKTGVITVNGVLDHEELHIHEIDVQAKD-LGPN 315

Query: 127 SDRLSSTATIHVNIIDDNDNYPQ---FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183
           S  + +   + VN+ID NDN P+    SE +  V V E+  +    VIA ++ +D D GA
Sbjct: 316 S--IPAHCKVIVNVIDINDNAPEIKLLSENSEMVEVSENAPL--GYVIALVRVSDNDSGA 371

Query: 184 NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
           N  ++   + GN   + +       + +   LD EQ   Y L I A+D G P   ++   
Sbjct: 372 NGKVQ-CRLQGNVPFRLNEFESFSTLLVDGRLDREQRDMYNLTILAEDSGYPPLRSSKSF 430

Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
            + + D NDN P F    +Q  V EN   G  ++ V A D D G+N  ++Y +   +  G
Sbjct: 431 AVKVTDENDNPPYFTKPHYQAMVLENNVPGAFLLAVSARDPDLGMNGTVSYEIIKSEVRG 490

Query: 304 -NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT-----XXXXXX 357
            +V+  +T++  +G +Y     + E    ++  V+A DGGDPP ++ AT           
Sbjct: 491 MSVESYVTVN-SNGEIYGVRAFNHEDTRTFEFKVSAKDGGDPPLTSNATVRIVVLDVNDN 549

Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSIT 415
                    + G  EV + ++   G  V  + A D D  E+ RL Y I+ G+    F I 
Sbjct: 550 TPVMTTPPLVNGTAEVSIPKNAGVGYLVTQIKADDYDEGENGRLTYSISEGD-MAYFEID 608

Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYT 475
             NG   +   +      +  Y +TV A D G  S +A   I I  + +     +  P  
Sbjct: 609 QINGE--VRTTKTFGENAKPSYQITVVAHDHGQTSLSASAYIVIYLSPDLNAQEQIGPVN 666

Query: 476 ASVFEDAPIGTTVLVVSAT 494
            S+     +G+  +++  T
Sbjct: 667 LSLIFIIALGSIAVILFVT 685


>UniRef50_Q60I64 Cluster: Cadherin-related neuronal receptor
           constant; n=6; Clupeocephala|Rep: Cadherin-related
           neuronal receptor constant - Danio rerio (Zebrafish)
           (Brachydanio rerio)
          Length = 1009

 Score =  225 bits (550), Expect = 1e-56
 Identities = 171/592 (28%), Positives = 269/592 (45%), Gaps = 57/592 (9%)

Query: 4   PFCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
           PF  H   + +LD ND+SP+F   +Y+  + EGA  G       A D D   N+   Y +
Sbjct: 115 PFEQHSVDVEILDANDNSPLFPRDEYQLEISEGAQPGARFSIEGAQDSDDASNSVRHYRL 174

Query: 63  ---ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKA 119
              E +  D+  P                    DG+   L+ +   DRE +  +  L+ A
Sbjct: 175 TPNEHLALDSTKPP------------------ADGKQVELVLKKPFDRELLQSHQFLITA 216

Query: 120 TDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA 179
           TD  SP     S TA I+V ++D NDN P F    Y V + E+  V    ++ K+ ATD 
Sbjct: 217 TDGGSPPR---SGTARINVRVLDTNDNVPVFDSSVYKVKLRENSPV--GALVIKLNATDR 271

Query: 180 DVGANSAIRYAIIG---GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS 236
           D G+N  + Y+         +  FS+D+ SG++ +   +DYE+  SY + I+A D G  +
Sbjct: 272 DEGSNGEVYYSFSSYTPDKVRQMFSVDADSGEIRVKSNVDYEETNSYEMYIQAADRGQGA 331

Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
            +   ++++ + DVNDN P    S     V E+      +  +   D D G N +++  +
Sbjct: 332 VAVHCKVVVEVLDVNDNPPEIVLSSLSSPVREDARADTVVALISINDKDSGQNKQVSLDI 391

Query: 297 TDKDYTGNVDLPITIDP-RSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354
                    DLP  I   R+ + + TS  LDRET + Y + VTATDGG PP S++ T   
Sbjct: 392 IPP------DLPFKIKSFRNHYTIVTSALLDRETISSYNVTVTATDGGTPPLSSSMTVRV 445

Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRG-- 410
                      F    Y V ++E+  P  P+  + ATD D  E+ R+ Y I   N  G  
Sbjct: 446 EVADINDNPPRFKQTSYTVYVSENNAPSAPLCVIKATDPDAGENARITYTILTDNNHGVS 505

Query: 411 -RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAP 467
               ++ +   G +   +  DF++ R +   V A D+G    S  A V I I D+N+++P
Sbjct: 506 VGSYVSVKPATGEVYALRSFDFEKLREFHFQVKAQDNGVPPLSRVATVYIYIMDSNDHSP 565

Query: 468 VFENA-----PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522
            F  A       T ++   +  G  V    A D D G NA + Y+L         A    
Sbjct: 566 QFARAVANGSHSTETILRHSEAGVLVSRALAWDLDAGENAWLLYNLHH-------APELD 618

Query: 523 QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
            F I+  TG I T + +  +  + + LTV  RD G P+ S +T + ++V+++
Sbjct: 619 LFKIHEHTGEIRTTRRVIEDNSTVFSLTVHVRDHGSPARSASTTINVAVMEL 670



 Score =  223 bits (546), Expect = 4e-56
 Identities = 171/575 (29%), Positives = 254/575 (44%), Gaps = 26/575 (4%)

Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR-LVIRAQDGGSPSRSNTTQL 243
           SA R  I     +  F+I+  +G + +   +D E +  +      + D    S      +
Sbjct: 62  SARRIRISSDTARRYFNINHKTGKLVISDRIDRETLCEFSGTCTLSLDVVLESPFEQHSV 121

Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
            + I D NDN+P F    +Q  +SE    G       A D+D+  N+   Y +T  ++  
Sbjct: 122 DVEILDANDNSPLFPRDEYQLEISEGAQPGARFSIEGAQDSDDASNSVRHYRLTPNEHLA 181

Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
                   D +   +      DRE    +Q L+TATDGG PPRS TA             
Sbjct: 182 LDSTKPPADGKQVELVLKKPFDRELLQSHQFLITATDGGSPPRSGTARINVRVLDTNDNV 241

Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI---TGGNTRGRFSITSQN 418
             F    Y+V+L E+ P G  V+ L ATD DE  +  ++Y     T    R  FS+ + +
Sbjct: 242 PVFDSSVYKVKLRENSPVGALVIKLNATDRDEGSNGEVYYSFSSYTPDKVRQMFSVDADS 301

Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTA 476
           G   I V   +D+++   Y + + A D G  +      V + + D N+  P    +  ++
Sbjct: 302 GE--IRVKSNVDYEETNSYEMYIQAADRGQGAVAVHCKVVVEVLDVNDNPPEIVLSSLSS 359

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
            V EDA   T V ++S  D D G N Q+    S +I    +    + F  N  T  I T+
Sbjct: 360 PVREDARADTVVALISINDKDSGQNKQV----SLDIIPPDLPFKIKSFR-NHYT--IVTS 412

Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
            LLDRET+S Y +TVTA DGG P LS +  V + V D+NDN P FKQ  YT  + E+   
Sbjct: 413 ALLDRETISSYNVTVTATDGGTPPLSSSMTVRVEVADINDNPPRFKQTSYTVYVSENNAP 472

Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDR---EEGSFV-IDPASGVIRTNKALDRESVAT 652
              +  + ATD D G N RI Y +   +      GS+V + PA+G +   ++ D E +  
Sbjct: 473 SAPLCVIKATDPDAGENARITYTILTDNNHGVSVGSYVSVKPATGEVYALRSFDFEKLRE 532

Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF-----ESDCLTFYISENSPIGTTIG 707
              +  A D G PP S    V+I I D ND  P F          T  I  +S  G  + 
Sbjct: 533 FHFQVKAQDNGVPPLSRVATVYIYIMDSNDHSPQFARAVANGSHSTETILRHSEAGVLVS 592

Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
              A D D G NA + Y++    + + F +    G
Sbjct: 593 RALAWDLDAGENAWLLYNLHHAPELDLFKIHEHTG 627



 Score =  208 bits (507), Expect = 2e-51
 Identities = 158/603 (26%), Positives = 264/603 (43%), Gaps = 21/603 (3%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F I+ ++G L+    +DRE +  ++     T     V +      ++ V I+D NDN P 
Sbjct: 77  FNINHKTGKLVISDRIDRETLCEFSGT--CTLSLDVVLESPFEQHSVDVEILDANDNSPL 134

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN----TQMQFSIDSL 205
           F    Y + + E          +   A D+D  +NS   Y +           +   D  
Sbjct: 135 FPRDEYQLEISE--GAQPGARFSIEGAQDSDDASNSVRHYRLTPNEHLALDSTKPPADGK 192

Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265
             ++ L K  D E ++S++ +I A DGGSP RS T ++ + + D NDN P F +S+++  
Sbjct: 193 QVELVLKKPFDRELLQSHQFLITATDGGSPPRSGTARINVRVLDTNDNVPVFDSSVYKVK 252

Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT-GNVDLPITIDPRSGWVYTSGQL 324
           + EN P+G  ++++ A D DEG N E+ Y+ +   YT   V    ++D  SG +     +
Sbjct: 253 LRENSPVGALVIKLNATDRDEGSNGEVYYSFS--SYTPDKVRQMFSVDADSGEIRVKSNV 310

Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
           D E    Y++ + A D G    +                   +       + ED    T 
Sbjct: 311 DYEETNSYEMYIQAADRGQGAVAVHCKVVVEVLDVNDNPPEIVLSSLSSPVREDARADTV 370

Query: 385 VVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444
           V  ++  D D        +        F I S      I  +  LD +    Y +TV+AT
Sbjct: 371 VALISINDKDSGQNKQVSLDIIPPDLPFKIKSFRNHYTIVTSALLDRETISSYNVTVTAT 430

Query: 445 DSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502
           D G    S +  V++ + D N+  P F+   YT  V E+      + V+ ATD D G NA
Sbjct: 431 DGGTPPLSSSMTVRVEVADINDNPPRFKQTSYTVYVSENNAPSAPLCVIKATDPDAGENA 490

Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
           +ITY++ ++ +N  V+       + P TG +   +  D E +  +   V A+D GVP LS
Sbjct: 491 RITYTILTD-NNHGVS-VGSYVSVKPATGEVYALRSFDFEKLREFHFQVKAQDNGVPPLS 548

Query: 563 DTTDVEISVVDVNDNEPVFKQQL-----YTANIMEDALVGTSVSQVGATDADVGLNGRIH 617
               V I ++D ND+ P F + +      T  I+  +  G  VS+  A D D G N  + 
Sbjct: 549 RVATVYIYIMDSNDHSPQFARAVANGSHSTETILRHSEAGVLVSRALAWDLDAGENAWLL 608

Query: 618 YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
           Y L     E   F I   +G IRT + +  ++     L     D G+P +S++  +++ +
Sbjct: 609 YNLHHAP-ELDLFKIHEHTGEIRTTRRVIEDNSTVFSLTVHVRDHGSPARSASTTINVAV 667

Query: 678 EDI 680
            ++
Sbjct: 668 MEL 670



 Score =  200 bits (487), Expect = 6e-49
 Identities = 130/440 (29%), Positives = 225/440 (51%), Gaps = 22/440 (5%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRL--HYEITGGNTRGRFSITSQ-NGRGL 422
           F   +Y++E++E   PG       A D+D+ +    HY +T        S     +G+ +
Sbjct: 135 FPRDEYQLEISEGAQPGARFSIEGAQDSDDASNSVRHYRLTPNEHLALDSTKPPADGKQV 194

Query: 423 -ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVF 479
            + + +P D +  + +   ++ATD G   RS TA + + + D N+  PVF+++ Y   + 
Sbjct: 195 ELVLKKPFDRELLQSHQFLITATDGGSPPRSGTARINVRVLDTNDNVPVFDSSVYKVKLR 254

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           E++P+G  V+ ++ATD D G N ++ YS SS   ++      Q F ++  +G I     +
Sbjct: 255 ENSPVGALVIKLNATDRDEGSNGEVYYSFSSYTPDKV----RQMFSVDADSGEIRVKSNV 310

Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
           D E  + Y + + A D G  +++    V + V+DVNDN P       ++ + EDA   T 
Sbjct: 311 DYEETNSYEMYIQAADRGQGAVAVHCKVVVEVLDVNDNPPEIVLSSLSSPVREDARADTV 370

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG--VIRTNKALDRESVATHDLKA 657
           V+ +   D D G N ++  ++ P D     F I        I T+  LDRE+++++++  
Sbjct: 371 VALISINDKDSGQNKQVSLDIIPPDLP---FKIKSFRNHYTIVTSALLDRETISSYNVTV 427

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
            A DGGTPP SS++ V +++ DIND+PP F+    T Y+SEN+     +  I+A DPD G
Sbjct: 428 TATDGGTPPLSSSMTVRVEVADINDNPPRFKQTSYTVYVSENNAPSAPLCVIKATDPDAG 487

Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKA--ELVTMVDLDYESPRKKYELVIRAAS---P 772
            NA + Y+I   D+++  S+ +      A  E+  +   D+E  R+ +   ++A     P
Sbjct: 488 ENARITYTILT-DNNHGVSVGSYVSVKPATGEVYALRSFDFEKLRE-FHFQVKAQDNGVP 545

Query: 773 PLWNDVRVEILVTDVNDNAP 792
           PL     V I + D ND++P
Sbjct: 546 PLSRVATVYIYIMDSNDHSP 565



 Score =  160 bits (388), Expect = 6e-37
 Identities = 111/389 (28%), Positives = 176/389 (45%), Gaps = 15/389 (3%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           V + I DAN+ +P+F    Y   + E A  G    +  A DSD   N+   Y L+    N
Sbjct: 121 VDVEILDANDNSPLFPRDEYQLEISEGAQPGARFSIEGAQDSDDASNSVRHYRLTP---N 177

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
           E +A    +   + +   +   K  DRE +  +   +TA DGG P  S T  + + V+D 
Sbjct: 178 EHLALDSTKPPADGKQVELVLKKPFDRELLQSHQFLITATDGGSPPRSGTARINVRVLDT 237

Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP--KDREEGSFVI 632
           NDN PVF   +Y   + E++ VG  V ++ ATD D G NG ++Y       D+    F +
Sbjct: 238 NDNVPVFDSSVYKVKLRENSPVGALVIKLNATDRDEGSNGEVYYSFSSYTPDKVRQMFSV 297

Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692
           D  SG IR    +D E   ++++   A D G    +    V +++ D+ND+PP      L
Sbjct: 298 DADSGEIRVKSNVDYEETNSYEMYIQAADRGQGAVAVHCKVVVEVLDVNDNPPEIVLSSL 357

Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752
           +  + E++   T +  I  +D D G N  V   I   D       + +   +   +VT  
Sbjct: 358 SSPVREDARADTVVALISINDKDSGQNKQVSLDIIPPD----LPFKIKSFRNHYTIVTSA 413

Query: 753 DLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809
            LD E+    Y + + A    +PPL + + V + V D+NDN P  K         ++  P
Sbjct: 414 LLDRETI-SSYNVTVTATDGGTPPLSSSMTVRVEVADINDNPPRFKQTSYTVYVSENNAP 472

Query: 810 VGPFGRVPAYDADVTD--KLQYRILSGNN 836
             P   + A D D  +  ++ Y IL+ NN
Sbjct: 473 SAPLCVIKATDPDAGENARITYTILTDNN 501



 Score = 58.4 bits (135), Expect = 3e-06
 Identities = 48/185 (25%), Positives = 76/185 (41%), Gaps = 4/185 (2%)

Query: 630 FVIDPASGVIRTNKALDRESVATHD-LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688
           F I+  +G +  +  +DRE++        +++D           V ++I D ND+ P+F 
Sbjct: 77  FNINHKTGKLVISDRIDRETLCEFSGTCTLSLDVVLESPFEQHSVDVEILDANDNSPLFP 136

Query: 689 SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAEL 748
            D     ISE +  G       A D D+  N+V HY +   +     S +      + EL
Sbjct: 137 RDEYQLEISEGAQPGARFSIEGAQDSDDASNSVRHYRLTPNEHLALDSTKPPADGKQVEL 196

Query: 749 VTMVDLDYESPRKKYELVIR--AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKD 806
           V     D E  +    L+      SPP     R+ + V D NDN PV  D  +     ++
Sbjct: 197 VLKKPFDRELLQSHQFLITATDGGSPPRSGTARINVRVLDTNDNVPVF-DSSVYKVKLRE 255

Query: 807 CFPVG 811
             PVG
Sbjct: 256 NSPVG 260


>UniRef50_Q9Y5F3 Cluster: Protocadherin beta 1 precursor; n=260;
           Amniota|Rep: Protocadherin beta 1 precursor - Homo
           sapiens (Human)
          Length = 818

 Score =  225 bits (549), Expect = 2e-56
 Identities = 175/629 (27%), Positives = 289/629 (45%), Gaps = 40/629 (6%)

Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDG-GSPS 236
           +VG  +A    ++    +M F +   +GD+ + + LD E +  ++   V+  +     P 
Sbjct: 55  EVGKLAARGARLVSEGNKMHFRLHRKTGDLFVKEKLDRESLCGKADPCVLHFEVVLVEPL 114

Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
           +S   +  + + D+NDNAP F        + E+ P+G       A D D G+N    YT+
Sbjct: 115 QSFRAE--VRVFDINDNAPVFLNKEPLLKIPESTPLGSRFPLQSAQDLDVGLNGLQNYTL 172

Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
           +   Y        +  P+   +  +  LDRE Q +  L +TA DGG PP+S TA      
Sbjct: 173 SANGYFHLHTRFCSHGPKYAELVLNKPLDREEQPEVNLTITAVDGGSPPKSGTAHIHVVV 232

Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTR--GRF 412
                    F    Y  +++E+ P G+ V T+TA D DE  +  + Y +          F
Sbjct: 233 LDVNDHVPQFSRLVYRAQVSENSPNGSLVATVTAVDLDEGTNKAITYSLAQNPEAILKTF 292

Query: 413 SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENA 472
            I  QNG   + +  PLDF+    Y + + ATD GG S  + V + + D N+  P    +
Sbjct: 293 QIDPQNGE--VRLRGPLDFEAIETYDIDIQATDGGGLSAHSKVLVEVVDVNDNPPEVMVS 350

Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG- 531
             ++ + ED+P  T V + +  D D+ +  ++T  L            D  FVI P  G 
Sbjct: 351 SVSSPLPEDSPPQTVVALFTIRDRDIRVGGKVTCFL----------REDLPFVIKPTFGN 400

Query: 532 --AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589
             ++ T++ LDRE +SGY +T+ A D G PSLS  T +E+ + DVNDN P+F++  Y   
Sbjct: 401 SYSLVTDRSLDREEVSGYNITIVAMDTGPPSLSAETMIEVLISDVNDNPPIFREDSYILT 460

Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYE-LDPKDREEGSFV---IDPASGVIRTNKAL 645
           + E+      + +V A D D+G N +I Y  L PK+ +   F    I+  +G +   + +
Sbjct: 461 VRENNSPAVFIGKVHAEDLDLGENAQITYSLLPPKNGDLSVFAYISINSGNGKLYALRTM 520

Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV----FESDCL--TFYISEN 699
           D E++        A DGG    SS V V + + D ND+ P+     ++  L     +  +
Sbjct: 521 DYEAIQDFQFVVKATDGGFLSLSSQVTVRVVVLDDNDNRPMILYPLQNGTLPCNDLVPRS 580

Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759
           +  G  + ++ A D D G N+ + Y +    D   FS++ + G    E+ T+  +    P
Sbjct: 581 AEAGYLVTKVVAVDGDSGQNSWLSYHLLKATDLGLFSVQRQNG----EIHTLRQISERDP 636

Query: 760 --RKKYELVIRAASPPLWNDVRVEILVTD 786
             +K   LV     P L   V + IL+ D
Sbjct: 637 MMQKLIILVQDHGQPALSTTVSLNILLVD 665



 Score =  203 bits (496), Expect = 5e-50
 Identities = 180/605 (29%), Positives = 262/605 (43%), Gaps = 29/605 (4%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           FR+  ++G L  +  LDRE +           +   V    S  A   V + D NDN P 
Sbjct: 75  FRLHRKTGDLFVKEKLDRESLCGKADPCVLHFEVVLVEPLQSFRA--EVRVFDINDNAPV 132

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG---NTQMQF-SIDSL 205
           F  K   + + E   +     +    A D DVG N    Y +      +   +F S    
Sbjct: 133 FLNKEPLLKIPESTPLGSRFPLQ--SAQDLDVGLNGLQNYTLSANGYFHLHTRFCSHGPK 190

Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265
             ++ L K LD E+     L I A DGGSP +S T  + + + DVND+ P+F   +++  
Sbjct: 191 YAELVLNKPLDREEQPEVNLTITAVDGGSPPKSGTAHIHVVVLDVNDHVPQFSRLVYRAQ 250

Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325
           VSEN P G  +  V A D DEG N  +TY++        +     IDP++G V   G LD
Sbjct: 251 VSENSPNGSLVATVTAVDLDEGTNKAITYSLAQNPEA--ILKTFQIDPQNGEVRLRGPLD 308

Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
            E    Y + + ATDGG    SA +                M       L ED PP T V
Sbjct: 309 FEAIETYDIDIQATDGGG--LSAHSKVLVEVVDVNDNPPEVMVSSVSSPLPEDSPPQTVV 366

Query: 386 VTLTATDADEDNRLHYEITGGNTRG-RFSI--TSQNGRGLITVAQPLDFKQERRYVLTVS 442
              T    D D R+  ++T        F I  T  N   L+T  + LD ++   Y +T+ 
Sbjct: 367 ALFTI--RDRDIRVGGKVTCFLREDLPFVIKPTFGNSYSLVT-DRSLDREEVSGYNITIV 423

Query: 443 ATDSGGRSDTA--MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
           A D+G  S +A  M+++ I+D N+  P+F    Y  +V E+      +  V A D D+G 
Sbjct: 424 AMDTGPPSLSAETMIEVLISDVNDNPPIFREDSYILTVRENNSPAVFIGKVHAEDLDLGE 483

Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560
           NAQITYSL    + +          IN   G +   + +D E +  +   V A DGG  S
Sbjct: 484 NAQITYSLLPPKNGDLSVF--AYISINSGNGKLYALRTMDYEAIQDFQFVVKATDGGFLS 541

Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV------GTSVSQVGATDADVGLNG 614
           LS    V + V+D NDN P+    L    +  + LV      G  V++V A D D G N 
Sbjct: 542 LSSQVTVRVVVLDDNDNRPMILYPLQNGTLPCNDLVPRSAEAGYLVTKVVAVDGDSGQNS 601

Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674
            + Y L  K  + G F +   +G I T + +         L  +  D G P  S+TV ++
Sbjct: 602 WLSYHL-LKATDLGLFSVQRQNGEIHTLRQISERDPMMQKLIILVQDHGQPALSTTVSLN 660

Query: 675 IKIED 679
           I + D
Sbjct: 661 ILLVD 665



 Score =  172 bits (418), Expect = 1e-40
 Identities = 133/443 (30%), Positives = 209/443 (47%), Gaps = 22/443 (4%)

Query: 456 QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515
           ++ + D N+ APVF N      + E  P+G+   + SA D DVG+N    Y+LS+   N 
Sbjct: 120 EVRVFDINDNAPVFLNKEPLLKIPESTPLGSRFPLQSAQDLDVGLNGLQNYTLSA---NG 176

Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575
               H +     P+   +  NK LDRE      LT+TA DGG P  S T  + + V+DVN
Sbjct: 177 YFHLHTRFCSHGPKYAELVLNKPLDREEQPEVNLTITAVDGGSPPKSGTAHIHVVVLDVN 236

Query: 576 DNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE-GSFVIDP 634
           D+ P F + +Y A + E++  G+ V+ V A D D G N  I Y L         +F IDP
Sbjct: 237 DHVPQFSRLVYRAQVSENSPNGSLVATVTAVDLDEGTNKAITYSLAQNPEAILKTFQIDP 296

Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694
            +G +R    LD E++ T+D+   A DGG     S V+V  ++ D+ND+PP      ++ 
Sbjct: 297 QNGEVRLRGPLDFEAIETYDIDIQATDGGGLSAHSKVLV--EVVDVNDNPPEVMVSSVSS 354

Query: 695 YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDL 754
            + E+SP  T +      D D      V   ++   +   F ++   G+  + LVT   L
Sbjct: 355 PLPEDSPPQTVVALFTIRDRDIRVGGKVTCFLR---EDLPFVIKPTFGNSYS-LVTDRSL 410

Query: 755 DYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811
           D E     Y + I A     P L  +  +E+L++DVNDN P+ ++   I    ++  P  
Sbjct: 411 DREEV-SGYNITIVAMDTGPPSLSAETMIEVLISDVNDNPPIFREDSYILTVRENNSPAV 469

Query: 812 PFGRVPAYDADVTDKLQ--YRILSGNNANL-----ILLNETTGSMTLSPQLNTNVPKLAT 864
             G+V A D D+ +  Q  Y +L   N +L     I +N   G +     ++    +   
Sbjct: 470 FIGKVHAEDLDLGENAQITYSLLPPKNGDLSVFAYISINSGNGKLYALRTMDYEAIQDFQ 529

Query: 865 MEVSVTDGVNEIKAMMQLSVRLI 887
             V  TDG   +    Q++VR++
Sbjct: 530 FVVKATDG-GFLSLSSQVTVRVV 551



 Score =  163 bits (397), Expect = 5e-38
 Identities = 161/595 (27%), Positives = 250/595 (42%), Gaps = 59/595 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ V D ND++PVF  ++    + E    G+      A D D+G N    YT+       
Sbjct: 120 EVRVFDINDNAPVFLNKEPLLKIPESTPLGSRFPLQSAQDLDVGLNGLQNYTLS------ 173

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGA-LLTRASLDREKVARYTVLVKATDQASPVSD 128
                           +   F   G   A L+    LDRE+     + + A D  SP   
Sbjct: 174 ----------ANGYFHLHTRFCSHGPKYAELVLNKPLDREEQPEVNLTITAVDGGSPPK- 222

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             S TA IHV ++D ND+ PQFS   Y   V E  +  +  ++A + A D D G N AI 
Sbjct: 223 --SGTAHIHVVVLDVNDHVPQFSRLVYRAQVSE--NSPNGSLVATVTAVDLDEGTNKAIT 278

Query: 189 YAIIGGNTQM--QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           Y++      +   F ID  +G+V L   LD+E + +Y + I+A DGG  S    +++L+ 
Sbjct: 279 YSLAQNPEAILKTFQIDPQNGEVRLRGPLDFEAIETYDIDIQATDGGGLSAH--SKVLVE 336

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
           + DVNDN P    S     + E+ P    +      D D  V  ++T  + +       D
Sbjct: 337 VVDVNDNPPEVMVSSVSSPLPEDSPPQTVVALFTIRDRDIRVGGKVTCFLRE-------D 389

Query: 307 LPITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
           LP  I P  G  Y   T   LDRE  + Y + + A D G P  SA               
Sbjct: 390 LPFVIKPTFGNSYSLVTDRSLDREEVSGYNITIVAMDTGPPSLSAETMIEVLISDVNDNP 449

Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEI---TGGNTRGRFSITSQN 418
             F    Y + + E+  P   +  + A D D  E+ ++ Y +     G+      I+  +
Sbjct: 450 PIFREDSYILTVRENNSPAVFIGKVHAEDLDLGENAQITYSLLPPKNGDLSVFAYISINS 509

Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPV----FENA 472
           G G +   + +D++  + +   V ATD G    S    V++ + D N+  P+     +N 
Sbjct: 510 GNGKLYALRTMDYEAIQDFQFVVKATDGGFLSLSSQVTVRVVVLDDNDNRPMILYPLQNG 569

Query: 473 --PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
             P    V   A  G  V  V A D D G N+ ++Y L         A     F +  Q 
Sbjct: 570 TLPCNDLVPRSAEAGYLVTKVVAVDGDSGQNSWLSYHLLK-------ATDLGLFSVQRQN 622

Query: 531 GAI-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584
           G I T  ++ +R+ M   L+ +  +D G P+LS T  + I +VD   +EP  + Q
Sbjct: 623 GEIHTLRQISERDPMMQKLI-ILVQDHGQPALSTTVSLNILLVD-GFSEPYLQFQ 675



 Score =  142 bits (344), Expect = 1e-31
 Identities = 132/464 (28%), Positives = 201/464 (43%), Gaps = 41/464 (8%)

Query: 8   HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
           H  + VLD NDH P F    Y A V E + +G+ V T+ A D D G N  + Y++     
Sbjct: 227 HIHVVVLDVNDHVPQFSRLVYRAQVSENSPNGSLVATVTAVDLDEGTNKAITYSL----- 281

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
              NPE            +   F+ID ++G +  R  LD E +  Y + ++ATD      
Sbjct: 282 -AQNPE-----------AILKTFQIDPQNGEVRLRGPLDFEAIETYDIDIQATDGGG--- 326

Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
             LS+ + + V ++D NDN P+    + +  + ED       V+A     D D+     +
Sbjct: 327 --LSAHSKVLVEVVDVNDNPPEVMVSSVSSPLPED--SPPQTVVALFTIRDRDIRVGGKV 382

Query: 188 RYAIIGGNTQMQFSIDSLSGD-VSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
              +      + F I    G+  SLV  ++LD E+V  Y + I A D G PS S  T + 
Sbjct: 383 TCFL---REDLPFVIKPTFGNSYSLVTDRSLDREEVSGYNITIVAMDTGPPSLSAETMIE 439

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT-MTDKDYTG 303
           + I DVNDN P F    +  +V EN      I +V A D D G NA++TY+ +  K+   
Sbjct: 440 VLISDVNDNPPIFREDSYILTVRENNSPAVFIGKVHAEDLDLGENAQITYSLLPPKNGDL 499

Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
           +V   I+I+  +G +Y    +D E    +Q +V ATDGG    S+  T            
Sbjct: 500 SVFAYISINSGNGKLYALRTMDYEAIQDFQFVVKATDGGFLSLSSQVTVRVVVLDDNDNR 559

Query: 364 XXFM-PGQYEVELAEDEPP-----GTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSIT 415
              + P Q       D  P     G  V  + A D D  +++ L Y +      G FS+ 
Sbjct: 560 PMILYPLQNGTLPCNDLVPRSAEAGYLVTKVVAVDGDSGQNSWLSYHLLKATDLGLFSVQ 619

Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINI 459
            QNG   I   + +  +      L +   D G  + +  V +NI
Sbjct: 620 RQNGE--IHTLRQISERDPMMQKLIILVQDHGQPALSTTVSLNI 661


>UniRef50_Q60H65 Cluster: Protocadherin1-alpha-av15-vCP; n=75;
           Eukaryota|Rep: Protocadherin1-alpha-av15-vCP - Danio
           rerio (Zebrafish) (Brachydanio rerio)
          Length = 939

 Score =  224 bits (548), Expect = 2e-56
 Identities = 171/612 (27%), Positives = 280/612 (45%), Gaps = 36/612 (5%)

Query: 87  QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIH---VNIIDD 143
           + +F ++   G L  +  LDRE V       ++T     +   L +   IH   V++ID 
Sbjct: 74  ESMFSVNQNDGVLYVKGKLDRENVCE-----RSTPCLINLKIALENPLEIHYVTVDVIDV 128

Query: 144 NDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSID 203
           ND+ P F E+   + + E  +V          A D D G+NS   Y +       +  I 
Sbjct: 129 NDHAPMFPEQEKRLEISE--TVLPGARFQLQAARDPDSGSNSVQTYKL-SHTEYFRIEIK 185

Query: 204 SLSGD-----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY 258
               D     + L K LD E  +S +L + A DGG P +S    ++I++ D+NDNAP F 
Sbjct: 186 DRYEDGKVPVLILQKPLDREVTKSIKLQLTALDGGRPPKSGKMTIIIDVLDINDNAPVFI 245

Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV 318
             ++  +++EN P+G +I+RV A D DEG N  + Y++   D    +     ++P +G +
Sbjct: 246 KEVYSVTLNENTPVGTTILRVNATDLDEGQNGVVVYSL-GHDVNDKLRKLFNVNPVTGEI 304

Query: 319 YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAED 378
             +G LD E +  Y++ + A+D G  P +   +                       + ED
Sbjct: 305 VVTGLLDFEVKDIYEIDIQASDKGIAPLTTDKSVTIKIADVNDNEPQIEVTSLSSTIPED 364

Query: 379 EPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436
             PGT V  ++ +D D   + R+   ++          + +N   L+T +  LD +    
Sbjct: 365 SKPGTTVALISVSDLDSGINGRVTCSLSENIPFQLMPSSQENTYSLVTTS-ALDRETIAH 423

Query: 437 YVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494
           Y +T+ A D+G    S    V + I+D N+ +P F ++PY   V E+   G ++  VSA+
Sbjct: 424 YDITLEAKDAGQPPLSSVKSVTVQISDVNDNSPEFSSSPYAFYVMENNAPGKSLFSVSAS 483

Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETMSGYLLTVTA 553
           D D G N+ ++Y +  +   E   +    F+ IN + G I   K  D ET   +   + A
Sbjct: 484 DKDTGENSAVSYQIWRDGGAE---NKFTSFININSENGEIYALKSFDFETSKTFQFHILA 540

Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN--------IMEDALVGTSVSQVGA 605
            D G PSLS    V + ++D NDN PV    + +AN        I  +   G  V++V A
Sbjct: 541 TDSGSPSLSSNVTVNVFILDQNDNVPVILYPV-SANGSAEGVEEIPRNVNAGHLVTKVRA 599

Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
            DAD+G NG + + L  +  E   F +D  +G IRT ++      A H L  +  D G  
Sbjct: 600 YDADIGYNGWLLFSLQ-EVSEHSLFALDRYTGQIRTLRSFTETDEAQHKLVILVKDNGNV 658

Query: 666 PQSSTVIVHIKI 677
             S+T  V +K+
Sbjct: 659 SLSATATVIVKV 670



 Score =  217 bits (531), Expect = 3e-54
 Identities = 150/500 (30%), Positives = 239/500 (47%), Gaps = 24/500 (4%)

Query: 310 TIDPRSGWVYTSGQLDRET--QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
           +++   G +Y  G+LDRE   +     L+      + P                    F 
Sbjct: 78  SVNQNDGVLYVKGKLDRENVCERSTPCLINLKIALENPLEIHYVTVDVIDVNDHAPM-FP 136

Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG-RFSITSQNGRGLITVA 426
             +  +E++E   PG       A D D  +         +T   R  I  +   G + V 
Sbjct: 137 EQEKRLEISETVLPGARFQLQAARDPDSGSNSVQTYKLSHTEYFRIEIKDRYEDGKVPVL 196

Query: 427 ---QPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFED 481
              +PLD +  +   L ++A D G   +S    + I++ D N+ APVF    Y+ ++ E+
Sbjct: 197 ILQKPLDREVTKSIKLQLTALDGGRPPKSGKMTIIIDVLDINDNAPVFIKEVYSVTLNEN 256

Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
            P+GTT+L V+ATD D G N  + YSL  +++++      + F +NP TG I    LLD 
Sbjct: 257 TPVGTTILRVNATDLDEGQNGVVVYSLGHDVNDKL----RKLFNVNPVTGEIVVTGLLDF 312

Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
           E    Y + + A D G+  L+    V I + DVNDNEP  +    ++ I ED+  GT+V+
Sbjct: 313 EVKDIYEIDIQASDKGIAPLTTDKSVTIKIADVNDNEPQIEVTSLSSTIPEDSKPGTTVA 372

Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV----IRTNKALDRESVATHDLKA 657
            +  +D D G+NGR+   L     E   F + P+S      + T  ALDRE++A +D+  
Sbjct: 373 LISVSDLDSGINGRVTCSLS----ENIPFQLMPSSQENTYSLVTTSALDRETIAHYDITL 428

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
            A D G PP SS   V ++I D+ND+ P F S    FY+ EN+  G ++  + A D D G
Sbjct: 429 EAKDAGQPPLSSVKSVTVQISDVNDNSPEFSSSPYAFYVMENNAPGKSLFSVSASDKDTG 488

Query: 718 PNAVVHYSI-KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR--KKYELVIRAASPPL 774
            N+ V Y I + G   N F+      S+  E+  +   D+E+ +  + + L   + SP L
Sbjct: 489 ENSAVSYQIWRDGGAENKFTSFININSENGEIYALKSFDFETSKTFQFHILATDSGSPSL 548

Query: 775 WNDVRVEILVTDVNDNAPVM 794
            ++V V + + D NDN PV+
Sbjct: 549 SSNVTVNVFILDQNDNVPVI 568



 Score =  213 bits (520), Expect = 6e-53
 Identities = 168/574 (29%), Positives = 260/574 (45%), Gaps = 29/574 (5%)

Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDGGSPSRSNTTQLLIN 246
           + I+  + +  FS++   G + +   LD E V  RS   +I  +     +      + ++
Sbjct: 66  FRIVSTSGESMFSVNQNDGVLYVKGKLDRENVCERSTPCLINLKIA-LENPLEIHYVTVD 124

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
           + DVND+AP F     +  +SE V  G       A D D G N+  TY ++  +Y     
Sbjct: 125 VIDVNDHAPMFPEQEKRLEISETVLPGARFQLQAARDPDSGSNSVQTYKLSHTEYFRIEI 184

Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
                D +   +     LDRE     +L +TA DGG PP+S   T              F
Sbjct: 185 KDRYEDGKVPVLILQKPLDREVTKSIKLQLTALDGGRPPKSGKMTIIIDVLDINDNAPVF 244

Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEI---TGGNTRGRFSITSQNGRG 421
           +   Y V L E+ P GT ++ + ATD DE     + Y +        R  F++    G  
Sbjct: 245 IKEVYSVTLNENTPVGTTILRVNATDLDEGQNGVVVYSLGHDVNDKLRKLFNVNPVTGE- 303

Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTASVF 479
            I V   LDF+ +  Y + + A+D G    T    V I I D N+  P  E    ++++ 
Sbjct: 304 -IVVTGLLDFEVKDIYEIDIQASDKGIAPLTTDKSVTIKIADVNDNEPQIEVTSLSSTIP 362

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           ED+  GTTV ++S +D D GIN ++T SLS  I  + +    +       T ++ T   L
Sbjct: 363 EDSKPGTTVALISVSDLDSGINGRVTCSLSENIPFQLMPSSQEN------TYSLVTTSAL 416

Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
           DRET++ Y +T+ A+D G P LS    V + + DVNDN P F    Y   +ME+   G S
Sbjct: 417 DRETIAHYDITLEAKDAGQPPLSSVKSVTVQISDVNDNSPEFSSSPYAFYVMENNAPGKS 476

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFV----IDPASGVIRTNKALDRESVATHDL 655
           +  V A+D D G N  + Y++      E  F     I+  +G I   K+ D E+  T   
Sbjct: 477 LFSVSASDKDTGENSAVSYQIWRDGGAENKFTSFININSENGEIYALKSFDFETSKTFQF 536

Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF-------ESDCLTFYISENSPIGTTIGE 708
             +A D G+P  SS V V++ I D ND+ PV         S      I  N   G  + +
Sbjct: 537 HILATDSGSPSLSSNVTVNVFILDQNDNVPVILYPVSANGSAEGVEEIPRNVNAGHLVTK 596

Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
           +RA+D D G N  + +S++   + + F+L+   G
Sbjct: 597 VRAYDADIGYNGWLLFSLQEVSEHSLFALDRYTG 630



 Score =  195 bits (475), Expect = 2e-47
 Identities = 157/594 (26%), Positives = 270/594 (45%), Gaps = 60/594 (10%)

Query: 4   PFCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
           P  IH   ++V+D NDH+P+F  Q+    + E    G       A D D G N+   Y +
Sbjct: 115 PLEIHYVTVDVIDVNDHAPMFPEQEKRLEISETVLPGARFQLQAARDPDSGSNSVQTYKL 174

Query: 63  ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122
                                  ++D +  DG+   L+ +  LDRE      + + A D 
Sbjct: 175 S--------------HTEYFRIEIKDRYE-DGKVPVLILQKPLDREVTKSIKLQLTALDG 219

Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
             P     S   TI ++++D NDN P F ++ Y+V+++E+  V     I ++ ATD D G
Sbjct: 220 GRPPK---SGKMTIIIDVLDINDNAPVFIKEVYSVTLNENTPV--GTTILRVNATDLDEG 274

Query: 183 ANSAIRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239
            N  + Y++   +    +  F+++ ++G++ +   LD+E    Y + I+A D G    + 
Sbjct: 275 QNGVVVYSLGHDVNDKLRKLFNVNPVTGEIVVTGLLDFEVKDIYEIDIQASDKGIAPLTT 334

Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
              + I I DVNDN P+   +    ++ E+   G ++  +   D D G+N  +T ++++ 
Sbjct: 335 DKSVTIKIADVNDNEPQIEVTSLSSTIPEDSKPGTTVALISVSDLDSGINGRVTCSLSE- 393

Query: 300 DYTGNVDLPITIDPRSGW----VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355
                 ++P  + P S      + T+  LDRET A Y + + A D G PP S+  +    
Sbjct: 394 ------NIPFQLMPSSQENTYSLVTTSALDRETIAHYDITLEAKDAGQPPLSSVKSVTVQ 447

Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEI-TGGNTRGRF 412
                     F    Y   + E+  PG  + +++A+D D  E++ + Y+I   G    +F
Sbjct: 448 ISDVNDNSPEFSSSPYAFYVMENNAPGKSLFSVSASDKDTGENSAVSYQIWRDGGAENKF 507

Query: 413 S----ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYA 466
           +    I S+NG   I   +  DF+  + +   + ATDSG  S ++ V +N  I D N+  
Sbjct: 508 TSFININSENGE--IYALKSFDFETSKTFQFHILATDSGSPSLSSNVTVNVFILDQNDNV 565

Query: 467 PVF---ENAPYTASVFEDAP----IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAH 519
           PV     +A  +A   E+ P     G  V  V A D+D+G N  + +SL  E+S  ++  
Sbjct: 566 PVILYPVSANGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQ-EVSEHSL-- 622

Query: 520 HDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
               F ++  TG I T +       + + L +  +D G  SLS T  V + VV+
Sbjct: 623 ----FALDRYTGQIRTLRSFTETDEAQHKLVILVKDNGNVSLSATATVIVKVVE 672



 Score =  161 bits (392), Expect = 2e-37
 Identities = 126/429 (29%), Positives = 191/429 (44%), Gaps = 19/429 (4%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           V +++ D N++AP+F        + E    G    + +A D D G N+  TY LS     
Sbjct: 121 VTVDVIDVNDHAPMFPEQEKRLEISETVLPGARFQLQAARDPDSGSNSVQTYKLSH---T 177

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
           E      +    + +   +   K LDRE      L +TA DGG P  S    + I V+D+
Sbjct: 178 EYFRIEIKDRYEDGKVPVLILQKPLDREVTKSIKLQLTALDGGRPPKSGKMTIIIDVLDI 237

Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDREEGSFVI 632
           NDN PVF +++Y+  + E+  VGT++ +V ATD D G NG + Y L  D  D+    F +
Sbjct: 238 NDNAPVFIKEVYSVTLNENTPVGTTILRVNATDLDEGQNGVVVYSLGHDVNDKLRKLFNV 297

Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692
           +P +G I     LD E    +++   A D G  P ++   V IKI D+ND+ P  E   L
Sbjct: 298 NPVTGEIVVTGLLDFEVKDIYEIDIQASDKGIAPLTTDKSVTIKIADVNDNEPQIEVTSL 357

Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752
           +  I E+S  GTT+  I   D D G N  V  S+    ++  F L      +   LVT  
Sbjct: 358 SSTIPEDSKPGTTVALISVSDLDSGINGRVTCSLS---ENIPFQLMPSSQENTYSLVTTS 414

Query: 753 DLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809
            LD E+    Y++ + A     PPL +   V + ++DVNDN+P        F   ++  P
Sbjct: 415 ALDRETIAH-YDITLEAKDAGQPPLSSVKSVTVQISDVNDNSPEFSSSPYAFYVMENNAP 473

Query: 810 VGPFGRVPAYDADVTDK--LQYRILSGNNA-----NLILLNETTGSMTLSPQLNTNVPKL 862
                 V A D D  +   + Y+I     A     + I +N   G +      +    K 
Sbjct: 474 GKSLFSVSASDKDTGENSAVSYQIWRDGGAENKFTSFININSENGEIYALKSFDFETSKT 533

Query: 863 ATMEVSVTD 871
               +  TD
Sbjct: 534 FQFHILATD 542



 Score =  123 bits (297), Expect = 6e-26
 Identities = 100/323 (30%), Positives = 148/323 (45%), Gaps = 15/323 (4%)

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
           S+ E+   GT V  V+    D+GI+ +        I + +    +  F +N   G +   
Sbjct: 36  SISEEQKDGTAVGNVA---KDLGIDPKTLKERGFRIVSTS---GESMFSVNQNDGVLYVK 89

Query: 537 KLLDRETMSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
             LDRE +              + +  +   V + V+DVND+ P+F +Q     I E  L
Sbjct: 90  GKLDRENVCERSTPCLINLKIALENPLEIHYVTVDVIDVNDHAPMFPEQEKRLEISETVL 149

Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDR---EEGSFVIDPASGVIRTNKALDRESVAT 652
            G       A D D G N    Y+L   +    E      D    V+   K LDRE   +
Sbjct: 150 PGARFQLQAARDPDSGSNSVQTYKLSHTEYFRIEIKDRYEDGKVPVLILQKPLDREVTKS 209

Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
             L+  A+DGG PP+S  + + I + DIND+ PVF  +  +  ++EN+P+GTTI  + A 
Sbjct: 210 IKLQLTALDGGRPPKSGKMTIIIDVLDINDNAPVFIKEVYSVTLNENTPVGTTILRVNAT 269

Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS- 771
           D DEG N VV YS+ G D ++             E+V    LD+E  +  YE+ I+A+  
Sbjct: 270 DLDEGQNGVVVYSL-GHDVNDKLRKLFNVNPVTGEIVVTGLLDFE-VKDIYEIDIQASDK 327

Query: 772 --PPLWNDVRVEILVTDVNDNAP 792
              PL  D  V I + DVNDN P
Sbjct: 328 GIAPLTTDKSVTIKIADVNDNEP 350


>UniRef50_Q4SNX9 Cluster: Chromosome 15 SCAF14542, whole genome
           shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 15
           SCAF14542, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1074

 Score =  221 bits (541), Expect = 2e-55
 Identities = 179/618 (28%), Positives = 281/618 (45%), Gaps = 38/618 (6%)

Query: 91  RIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQF 150
           R+    G L     +DRE++ ++T            S        + V + D NDN P+F
Sbjct: 73  RLRESDGQLSIGERIDRERICKHTSQCLIAFDVVSFSKEQFKLIHVEVEVKDINDNTPEF 132

Query: 151 SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS---- 206
             K  ++ + E+ +V     I    A D DVG+N    Y I   +    FSID LS    
Sbjct: 133 PRKESSLEISENTAVGTR--IPLDFAADDDVGSNYIQSYQI---SVNSHFSIDVLSRADG 187

Query: 207 ---GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263
               ++ L+K LD E   SY L + A DGGSPSR+ TT++ + ++D NDN+P F  + F 
Sbjct: 188 VKYAELVLMKELDRETQASYALELVAVDGGSPSRTGTTRVNVRVKDYNDNSPVFDRNSFS 247

Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323
             + E+ P+G  ++ + A D DEG+N E+ Y    +  T  +     +D +SG +    Q
Sbjct: 248 VDLPEDAPVGTLLLDLNAEDPDEGLNGEVVYGFGHQVPT-EIRQLFRVDRKSGRLTLESQ 306

Query: 324 LDRETQAKYQLLVTATDGGDPPRSATA--------TXXXXXXXXXXXXXXFMPGQYEVEL 375
           +D E++  Y+  V ATD G  P  A                            G   +  
Sbjct: 307 IDFESKNTYEFDVQATDLGPNPSPAVCKIVVQVQDVNDNAPEISITPMTSITAGIAYITE 366

Query: 376 AEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435
           A        +V+ +  D+  + ++H  +  G+   R     ++   +I    PLD ++  
Sbjct: 367 AAARESFVALVSTSDRDSGANGQVHCTLY-GHDHFRLQQAYEDS-FMIVSTSPLDREKIP 424

Query: 436 RYVLTVSATDSGGRSDTAMVQ--INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
            Y LTV A D G      + Q  I +TD N+ APVF    Y  S+ E+   G  +  V A
Sbjct: 425 EYNLTVVAEDLGSPPFRTITQYTIRLTDENDNAPVFSKPVYEVSMVENNAPGAYIATVVA 484

Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETMSGYLLTVT 552
            D D G+N +++Y L+    +  +      FV ++P +G++   +  + E M    L +T
Sbjct: 485 RDLDTGLNGKVSYKLA---DSYFMGSPISTFVSLDPASGSLYALRSFNYEVMKQLELRIT 541

Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ-QLYTAN----IMEDALVGTSVSQVGATD 607
           A D G P LS T +V + +VD NDN P+  Q  L+  +    +  DA  G  V++V A D
Sbjct: 542 ASDAGSPPLSGTANVYVKMVDQNDNAPLITQPPLHNGSAEVLLPRDAPSGYVVTRVEARD 601

Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
           AD G+N  + Y L     E   F I+  +G I  ++AL+ +   T  +     DGG P  
Sbjct: 602 ADEGMNSAVSYAL--AAGELSVFSINKDTGEIYLSQALNHDVDQTLSVTVTVSDGGRPAL 659

Query: 668 SSTVIVHIKIEDINDSPP 685
           +ST  +H  +  I  SPP
Sbjct: 660 TSTATLHFLV--IEGSPP 675



 Score =  212 bits (517), Expect = 1e-52
 Identities = 158/523 (30%), Positives = 245/523 (46%), Gaps = 38/523 (7%)

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           + ++D+NDN P F        +SEN  +G  I    A D D G N   +Y ++   +  +
Sbjct: 120 VEVKDINDNTPEFPRKESSLEISENTAVGTRIPLDFAADDDVGSNYIQSYQISVNSHF-S 178

Query: 305 VDLPITIDP-RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
           +D+    D  +   +    +LDRETQA Y L + A DGG P R+ T              
Sbjct: 179 IDVLSRADGVKYAELVLMKELDRETQASYALELVAVDGGSPSRTGTTRVNVRVKDYNDNS 238

Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG-------NTRGRFSITS 416
             F    + V+L ED P GT ++ L A D DE   L+ E+  G         R  F +  
Sbjct: 239 PVFDRNSFSVDLPEDAPVGTLLLDLNAEDPDEG--LNGEVVYGFGHQVPTEIRQLFRVDR 296

Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPY 474
           ++GR  +T+   +DF+ +  Y   V ATD G     A+  + + + D N+ AP     P 
Sbjct: 297 KSGR--LTLESQIDFESKNTYEFDVQATDLGPNPSPAVCKIVVQVQDVNDNAPEISITPM 354

Query: 475 T------ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528
           T      A + E A   + V +VS +D D G N Q+  +L           ++  F+I  
Sbjct: 355 TSITAGIAYITEAAARESFVALVSTSDRDSGANGQVHCTLYGHDHFRLQQAYEDSFMI-- 412

Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588
               ++T+  LDRE +  Y LTV A D G P     T   I + D NDN PVF + +Y  
Sbjct: 413 ----VSTSP-LDREKIPEYNLTVVAEDLGSPPFRTITQYTIRLTDENDNAPVFSKPVYEV 467

Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK---DREEGSFV-IDPASGVIRTNKA 644
           +++E+   G  ++ V A D D GLNG++ Y+L           +FV +DPASG +   ++
Sbjct: 468 SMVENNAPGAYIATVVARDLDTGLNGKVSYKLADSYFMGSPISTFVSLDPASGSLYALRS 527

Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL-----TFYISEN 699
            + E +   +L+  A D G+PP S T  V++K+ D ND+ P+     L        +  +
Sbjct: 528 FNYEVMKQLELRITASDAGSPPLSGTANVYVKMVDQNDNAPLITQPPLHNGSAEVLLPRD 587

Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
           +P G  +  + A D DEG N+ V Y++  G+ S  FS+    G
Sbjct: 588 APSGYVVTRVEARDADEGMNSAVSYALAAGELS-VFSINKDTG 629



 Score =  182 bits (443), Expect = 1e-43
 Identities = 153/590 (25%), Positives = 257/590 (43%), Gaps = 57/590 (9%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           IH ++ V D ND++P F  ++    + E  + GT +    A D D+G N    Y I +  
Sbjct: 116 IHVEVEVKDINDNTPEFPRKESSLEISENTAVGTRIPLDFAADDDVGSNYIQSYQISV-- 173

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASP 125
                              +  + R DG +   L+    LDRE  A Y + + A D  SP
Sbjct: 174 --------------NSHFSIDVLSRADGVKYAELVLMKELDRETQASYALELVAVDGGSP 219

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
                + T  ++V + D NDN P F   +++V + ED  V    ++  + A D D G N 
Sbjct: 220 SR---TGTTRVNVRVKDYNDNSPVFDRNSFSVDLPEDAPV--GTLLLDLNAEDPDEGLNG 274

Query: 186 AIRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
            + Y     +    +  F +D  SG ++L   +D+E   +Y   ++A D G        +
Sbjct: 275 EVVYGFGHQVPTEIRQLFRVDRKSGRLTLESQIDFESKNTYEFDVQATDLGPNPSPAVCK 334

Query: 243 LLINIRDVNDNAPRF----YTSLFQ--ESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
           +++ ++DVNDNAP       TS+      ++E       +  V   D D G N ++  T+
Sbjct: 335 IVVQVQDVNDNAPEISITPMTSITAGIAYITEAAARESFVALVSTSDRDSGANGQVHCTL 394

Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
              D+     L    +  S  + ++  LDRE   +Y L V A D G PP           
Sbjct: 395 YGHDH---FRLQQAYED-SFMIVSTSPLDREKIPEYNLTVVAEDLGSPPFRTITQYTIRL 450

Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGR--- 411
                    F    YEV + E+  PG  + T+ A D D   + ++ Y++      G    
Sbjct: 451 TDENDNAPVFSKPVYEVSMVENNAPGAYIATVVARDLDTGLNGKVSYKLADSYFMGSPIS 510

Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVF 469
             ++     G +   +  +++  ++  L ++A+D+G    S TA V + + D N+ AP+ 
Sbjct: 511 TFVSLDPASGSLYALRSFNYEVMKQLELRITASDAGSPPLSGTANVYVKMVDQNDNAPLI 570

Query: 470 ENAPY---TASVF--EDAPIGTTVLVVSATDSDVGINAQITYSLSS-EISNEAVAHHDQQ 523
              P    +A V    DAP G  V  V A D+D G+N+ ++Y+L++ E+S          
Sbjct: 571 TQPPLHNGSAEVLLPRDAPSGYVVTRVEARDADEGMNSAVSYALAAGELS---------V 621

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
           F IN  TG I  ++ L+ +      +TVT  DGG P+L+ T  +   V++
Sbjct: 622 FSINKDTGEIYLSQALNHDVDQTLSVTVTVSDGGRPALTSTATLHFLVIE 671



 Score =  177 bits (430), Expect = 5e-42
 Identities = 140/473 (29%), Positives = 223/473 (47%), Gaps = 34/473 (7%)

Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480
           + + + LD + +  Y L + A D G   R+ T  V + + D N+ +PVF+   ++  + E
Sbjct: 193 LVLMKELDRETQASYALELVAVDGGSPSRTGTTRVNVRVKDYNDNSPVFDRNSFSVDLPE 252

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           DAP+GT +L ++A D D G+N ++ Y    ++  E      Q F ++ ++G +T    +D
Sbjct: 253 DAPVGTLLLDLNAEDPDEGLNGEVVYGFGHQVPTEI----RQLFRVDRKSGRLTLESQID 308

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT------ANIMEDA 594
            E+ + Y   V A D G         + + V DVNDN P       T      A I E A
Sbjct: 309 FESKNTYEFDVQATDLGPNPSPAVCKIVVQVQDVNDNAPEISITPMTSITAGIAYITEAA 368

Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654
              + V+ V  +D D G NG++H  L   D        + +  ++ T+  LDRE +  ++
Sbjct: 369 ARESFVALVSTSDRDSGANGQVHCTLYGHDHFRLQQAYEDSFMIVSTS-PLDREKIPEYN 427

Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
           L  VA D G+PP  +     I++ D ND+ PVF        + EN+  G  I  + A D 
Sbjct: 428 LTVVAEDLGSPPFRTITQYTIRLTDENDNAPVFSKPVYEVSMVENNAPGAYIATVVARDL 487

Query: 715 DEGPNAVVHYSI-----KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
           D G N  V Y +      G   S   SL+   GS    L  +   +YE   K+ EL I A
Sbjct: 488 DTGLNGKVSYKLADSYFMGSPISTFVSLDPASGS----LYALRSFNYE-VMKQLELRITA 542

Query: 770 A---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP-VGPFG----RVPAYDA 821
           +   SPPL     V + + D NDNAP++    +   + +   P   P G    RV A DA
Sbjct: 543 SDAGSPPLSGTANVYVKMVDQNDNAPLITQPPLHNGSAEVLLPRDAPSGYVVTRVEARDA 602

Query: 822 D--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
           D  +   + Y + +G   ++  +N+ TG + LS  LN +V +  ++ V+V+DG
Sbjct: 603 DEGMNSAVSYALAAG-ELSVFSINKDTGEIYLSQALNHDVDQTLSVTVTVSDG 654



 Score =  157 bits (380), Expect = 5e-36
 Identities = 125/456 (27%), Positives = 207/456 (45%), Gaps = 31/456 (6%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS--SEI 512
           V++ + D N+  P F     +  + E+  +GT + +  A D DVG N   +Y +S  S  
Sbjct: 118 VEVEVKDINDNTPEFPRKESSLEISENTAVGTRIPLDFAADDDVGSNYIQSYQISVNSHF 177

Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572
           S + ++  D       +   +   K LDRET + Y L + A DGG PS + TT V + V 
Sbjct: 178 SIDVLSRAD-----GVKYAELVLMKELDRETQASYALELVAVDGGSPSRTGTTRVNVRVK 232

Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE--GSF 630
           D NDN PVF +  ++ ++ EDA VGT +  + A D D GLNG + Y    +   E    F
Sbjct: 233 DYNDNSPVFDRNSFSVDLPEDAPVGTLLLDLNAEDPDEGLNGEVVYGFGHQVPTEIRQLF 292

Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690
            +D  SG +     +D ES  T++    A D G  P  +   + ++++D+ND+ P     
Sbjct: 293 RVDRKSGRLTLESQIDFESKNTYEFDVQATDLGPNPSPAVCKIVVQVQDVNDNAPEISIT 352

Query: 691 CLT------FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD 744
            +T       YI+E +   + +  +   D D G N  VH ++ G D    F L+ +   D
Sbjct: 353 PMTSITAGIAYITEAAARESFVALVSTSDRDSGANGQVHCTLYGHD---HFRLQ-QAYED 408

Query: 745 KAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801
              +V+   LD E    +Y L + A    SPP     +  I +TD NDNAPV        
Sbjct: 409 SFMIVSTSPLDREK-IPEYNLTVVAEDLGSPPFRTITQYTIRLTDENDNAPVFSKPVYEV 467

Query: 802 NNYKDCFPVGPFGRVPAYDAD--VTDKLQYRI-----LSGNNANLILLNETTGSMTLSPQ 854
           +  ++  P      V A D D  +  K+ Y++     +    +  + L+  +GS+     
Sbjct: 468 SMVENNAPGAYIATVVARDLDTGLNGKVSYKLADSYFMGSPISTFVSLDPASGSLYALRS 527

Query: 855 LNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITE 889
            N  V K   + ++ +D G   +     + V+++ +
Sbjct: 528 FNYEVMKQLELRITASDAGSPPLSGTANVYVKMVDQ 563



 Score = 78.2 bits (184), Expect = 3e-12
 Identities = 76/283 (26%), Positives = 127/283 (44%), Gaps = 15/283 (5%)

Query: 635 ASGVIRTNKALDRESVATHDLKA-VAIDGGTPPQSSTVIVHIKIE--DINDSPPVFESDC 691
           + G +   + +DRE +  H  +  +A D  +  +    ++H+++E  DIND+ P F    
Sbjct: 77  SDGQLSIGERIDRERICKHTSQCLIAFDVVSFSKEQFKLIHVEVEVKDINDNTPEFPRKE 136

Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751
            +  ISEN+ +GT I    A D D G N +  Y I      +   L    G   AELV M
Sbjct: 137 SSLEISENTAVGTRIPLDFAADDDVGSNYIQSYQISVNSHFSIDVLSRADGVKYAELVLM 196

Query: 752 VDLDYESPRK-KYELV-IRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809
            +LD E+      ELV +   SP      RV + V D NDN+PV        +  +D  P
Sbjct: 197 KELDRETQASYALELVAVDGGSPSRTGTTRVNVRVKDYNDNSPVFDRNSFSVDLPEDA-P 255

Query: 810 VGP-FGRVPAYDAD--VTDKLQYRI---LSGNNANLILLNETTGSMTLSPQLNTNVPKLA 863
           VG     + A D D  +  ++ Y     +      L  ++  +G +TL  Q++       
Sbjct: 256 VGTLLLDLNAEDPDEGLNGEVVYGFGHQVPTEIRQLFRVDRKSGRLTLESQIDFESKNTY 315

Query: 864 TMEVSVTD-GVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTA 905
             +V  TD G N   A+ ++ V++  +++  N+  + +  MT+
Sbjct: 316 EFDVQATDLGPNPSPAVCKIVVQV--QDVNDNAPEISITPMTS 356


>UniRef50_Q3V7B0 Cluster: Protocadherin alpha; n=22; Tetrapoda|Rep:
           Protocadherin alpha - Macaca fuscata (Japanese macaque)
          Length = 937

 Score =  221 bits (541), Expect = 2e-55
 Identities = 173/616 (28%), Positives = 280/616 (45%), Gaps = 31/616 (5%)

Query: 88  DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
           D+  ++ ++G L   + +DRE++   +   + +     + DR      + V + D NDN 
Sbjct: 73  DLLEVNLQNGILFVNSRIDREELCGRSA--ECSIHLEVIVDRPLQVFHVDVEVKDINDNP 130

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
           P F      + + E   +     +    A+DAD+G N+ + Y +   N      + + + 
Sbjct: 131 PVFPATQKNLFIAESRPLDSRFPLEG--ASDADIGENALLTYRL-SPNEYFSLDVPTSNQ 187

Query: 208 DVS-----LVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLF 262
            V      L K LD E+     L++ A DGG P  + T QLLI + DVNDNAP F  +L+
Sbjct: 188 QVKPLGLVLRKPLDREETPELHLLLTATDGGKPELTGTVQLLITVLDVNDNAPVFDRTLY 247

Query: 263 QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322
              + ENV IG  ++   A D DEG+N ++ Y+ +  D + ++     +DP SG +   G
Sbjct: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFS-SDVSPDIKSKFHMDPVSGAITVIG 306

Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382
            +D E    +++ V A D G  P +   T                     + ++ED  PG
Sbjct: 307 HMDFEESRAHKIPVEAVDKGFLPLAGHCTVLVEVVDVNDNAPQLTLTSLFLPISEDAQPG 366

Query: 383 TPVVTLTATDADEDNRLHYEITGGNT-RGRFSITS--QNGRGLITVAQPLDFKQERRYVL 439
           T V+TL +   D D  ++ ++T   T    F + S  +N   L+ +   LD +    Y L
Sbjct: 367 T-VITLISV-FDRDFGVNGQVTCSLTPHVPFKLVSTFKNYYSLV-LDSVLDRESVSAYEL 423

Query: 440 TVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497
            V+A D G  S   TA V + + D N+ AP F  + YT  V E+ P G  +  VSA D+D
Sbjct: 424 VVTARDGGSPSLWATASVSVEVADVNDNAPAFTQSEYTVFVKENNPPGCHIFTVSARDAD 483

Query: 498 VGINAQITYSL-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556
              NA ++YSL    +   A++ +     ++ ++G +   + LD E +      V+ARD 
Sbjct: 484 AQENALVSYSLVERRVGERALSSY---VSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQ-------LYTANIMEDALVGTSVSQVGATDAD 609
           GVPSLS    +++ V+D NDN PV             +  +      G  V++V A DAD
Sbjct: 541 GVPSLSSNATLQVFVLDENDNAPVLLAPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600

Query: 610 VGLNGRIHYELDP-KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
            G N  + YE  P        F +   +G I T +AL       H L  +  D G P  +
Sbjct: 601 SGYNAWLSYEFQPVAVSARIPFRVGLYTGEISTTRALGETDAPRHRLLVLVKDHGEPSLT 660

Query: 669 STVIVHIKIEDINDSP 684
           +T  V + + +   +P
Sbjct: 661 ATATVLVSLVESAQAP 676



 Score =  204 bits (498), Expect = 3e-50
 Identities = 157/549 (28%), Positives = 254/549 (46%), Gaps = 32/549 (5%)

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           + ++D+NDN P F  +     ++E+ P+        A DAD G NA LTY ++  +Y  +
Sbjct: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYF-S 179

Query: 305 VDLPITIDP-RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
           +D+P +    +   +     LDRE   +  LL+TATDGG P  + T              
Sbjct: 180 LDVPTSNQQVKPLGLVLRKPLDREETPELHLLLTATDGGKPELTGTVQLLITVLDVNDNA 239

Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGG---NTRGRFSITSQN 418
             F    Y V+L E+   GT V+   A+D DE  +  + Y  +     + + +F +   +
Sbjct: 240 PVFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPVS 299

Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTA 476
           G   ITV   +DF++ R + + V A D G    +    V + + D N+ AP         
Sbjct: 300 GA--ITVIGHMDFEESRAHKIPVEAVDKGFLPLAGHCTVLVEVVDVNDNAPQLTLTSLFL 357

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
            + EDA  GT + ++S  D D G+N Q+T SL+  +  + V+     +       ++  +
Sbjct: 358 PISEDAQPGTVITLISVFDRDFGVNGQVTCSLTPHVPFKLVSTFKNYY-------SLVLD 410

Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
            +LDRE++S Y L VTARDGG PSL  T  V + V DVNDN P F Q  YT  + E+   
Sbjct: 411 SVLDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFTQSEYTVFVKENNPP 470

Query: 597 GTSVSQVGATDADVGLNGRIHYELDPK---DREEGSFV-IDPASGVIRTNKALDRESVAT 652
           G  +  V A DAD   N  + Y L  +   +R   S+V +   SG +   + LD E +  
Sbjct: 471 GCHIFTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELEL 530

Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES-------DCLTFYISENSPIGTT 705
              +  A D G P  SS   + + + D ND+ PV  +         ++  +  +   G  
Sbjct: 531 LQFQVSARDAGVPSLSSNATLQVFVLDENDNAPVLLAPRVGGIGGAVSELVPRSVGAGHV 590

Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDL-DYESPRKKYE 764
           + ++RA D D G NA + Y  +    + S  +  R G    E+ T   L + ++PR +  
Sbjct: 591 VAKVRAVDADSGYNAWLSYEFQ--PVAVSARIPFRVGLYTGEISTTRALGETDAPRHRLL 648

Query: 765 LVIRAASPP 773
           ++++    P
Sbjct: 649 VLVKDHGEP 657



 Score =  187 bits (456), Expect = 3e-45
 Identities = 137/440 (31%), Positives = 220/440 (50%), Gaps = 18/440 (4%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGR--- 420
           F   Q  + +AE  P  +      A+DAD  E+  L Y ++  N      + + N +   
Sbjct: 133 FPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSP-NEYFSLDVPTSNQQVKP 191

Query: 421 -GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTAS 477
            GL+ + +PLD ++     L ++ATD G    T  VQ+ IT  D N+ APVF+   YT  
Sbjct: 192 LGLV-LRKPLDREETPELHLLLTATDGGKPELTGTVQLLITVLDVNDNAPVFDRTLYTVK 250

Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
           + E+  IGT V+  +A+D D G+N  I YS SS++S +  +    +F ++P +GAIT   
Sbjct: 251 LPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKS----KFHMDPVSGAITVIG 306

Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
            +D E    + + V A D G   L+    V + VVDVNDN P          I EDA  G
Sbjct: 307 HMDFEESRAHKIPVEAVDKGFLPLAGHCTVLVEVVDVNDNAPQLTLTSLFLPISEDAQPG 366

Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
           T ++ +   D D G+NG++   L P    +          ++  +  LDRESV+ ++L  
Sbjct: 367 TVITLISVFDRDFGVNGQVTCSLTPHVPFKLVSTFKNYYSLV-LDSVLDRESVSAYELVV 425

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
            A DGG+P   +T  V +++ D+ND+ P F     T ++ EN+P G  I  + A D D  
Sbjct: 426 TARDGGSPSLWATASVSVEVADVNDNAPAFTQSEYTVFVKENNPPGCHIFTVSARDADAQ 485

Query: 718 PNAVVHYS-IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIRAAS-PPL 774
            NA+V YS ++      + S      ++  ++  +  LD+E     ++++  R A  P L
Sbjct: 486 ENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPSL 545

Query: 775 WNDVRVEILVTDVNDNAPVM 794
            ++  +++ V D NDNAPV+
Sbjct: 546 SSNATLQVFVLDENDNAPVL 565



 Score =  169 bits (412), Expect = 7e-40
 Identities = 141/449 (31%), Positives = 208/449 (46%), Gaps = 23/449 (5%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS-SEIS 513
           V + + D N+  PVF        + E  P+ +   +  A+D+D+G NA +TY LS +E  
Sbjct: 119 VDVEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYF 178

Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
           +  V   +QQ  + P    +   K LDRE      L +TA DGG P L+ T  + I+V+D
Sbjct: 179 SLDVPTSNQQ--VKPL--GLVLRKPLDREETPELHLLLTATDGGKPELTGTVQLLITVLD 234

Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDREEGSFV 631
           VNDN PVF + LYT  + E+  +GT V    A+D D GLNG I Y    D     +  F 
Sbjct: 235 VNDNAPVFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFH 294

Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691
           +DP SG I     +D E    H +   A+D G  P +    V +++ D+ND+ P      
Sbjct: 295 MDPVSGAITVIGHMDFEESRAHKIPVEAVDKGFLPLAGHCTVLVEVVDVNDNAPQLTLTS 354

Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751
           L   ISE++  GT I  I   D D G N  V  S+        F L +   +  + ++  
Sbjct: 355 LFLPISEDAQPGTVITLISVFDRDFGVNGQVTCSLT---PHVPFKLVSTFKNYYSLVLDS 411

Query: 752 VDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCF 808
           V LD ES    YELV+ A    SP LW    V + V DVNDNAP     +      ++  
Sbjct: 412 V-LDRESV-SAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFTQSEYTVFVKENNP 469

Query: 809 PVGPFGRVPAYDADVTDK--LQYRILS---GNNA--NLILLNETTGSMTLSPQLNTNVPK 861
           P      V A DAD  +   + Y ++    G  A  + + ++  +G +     L+    +
Sbjct: 470 PGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELE 529

Query: 862 LATMEVSVTD-GVNEIKAMMQLSVRLITE 889
           L   +VS  D GV  + +   L V ++ E
Sbjct: 530 LLQFQVSARDAGVPSLSSNATLQVFVLDE 558



 Score =  146 bits (354), Expect = 8e-33
 Identities = 108/345 (31%), Positives = 164/345 (47%), Gaps = 28/345 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I VLD ND++PVF+   Y   + E  S GT V+   A+D D G N ++ Y+     +  +
Sbjct: 230 ITVLDVNDNAPVFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSF----SSDV 285

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           +P+            ++  F +D  SGA+     +D E+   + + V+A D+       L
Sbjct: 286 SPD------------IKSKFHMDPVSGAITVIGHMDFEESRAHKIPVEAVDKGFL---PL 330

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           +   T+ V ++D NDN PQ +  +  + + ED       VI  I   D D G N  +  +
Sbjct: 331 AGHCTVLVEVVDVNDNAPQLTLTSLFLPISED--AQPGTVITLISVFDRDFGVNGQVTCS 388

Query: 191 IIGGNTQMQFS-IDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
           +      + F  + +     SLV    LD E V +Y LV+ A+DGGSPS   T  + + +
Sbjct: 389 L---TPHVPFKLVSTFKNYYSLVLDSVLDRESVSAYELVVTARDGGSPSLWATASVSVEV 445

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN-VD 306
            DVNDNAP F  S +   V EN P G  I  V A DAD   NA ++Y++ ++      + 
Sbjct: 446 ADVNDNAPAFTQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALS 505

Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
             +++   SG VY    LD E     Q  V+A D G P  S+ AT
Sbjct: 506 SYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPSLSSNAT 550



 Score = 66.1 bits (154), Expect = 1e-08
 Identities = 55/212 (25%), Positives = 101/212 (47%), Gaps = 11/212 (5%)

Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV-IDPASGVIRTNKALDR 647
           ++ E+A  GT V ++ A D  + L+  +        +  G  + ++  +G++  N  +DR
Sbjct: 34  SVPEEAKHGTFVGRI-AQDLGLELSELVPRLFRAVCKFRGDLLEVNLQNGILFVNSRIDR 92

Query: 648 ESVATHDLK-AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706
           E +     + ++ ++           V ++++DIND+PPVF +     +I+E+ P+ +  
Sbjct: 93  EELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPPVFPATQKNLFIAESRPLDSRF 152

Query: 707 GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE---LVTMVDLDYESPRKKY 763
               A D D G NA++ Y +     +  FSL+    + + +   LV    LD E   + +
Sbjct: 153 PLEGASDADIGENALLTYRL---SPNEYFSLDVPTSNQQVKPLGLVLRKPLDREETPELH 209

Query: 764 ELVIR--AASPPLWNDVRVEILVTDVNDNAPV 793
            L+       P L   V++ I V DVNDNAPV
Sbjct: 210 LLLTATDGGKPELTGTVQLLITVLDVNDNAPV 241


>UniRef50_UPI0000F2DF7E Cluster: PREDICTED: similar to protocadherin
           8; n=1; Monodelphis domestica|Rep: PREDICTED: similar to
           protocadherin 8 - Monodelphis domestica
          Length = 955

 Score =  220 bits (538), Expect = 4e-55
 Identities = 168/552 (30%), Positives = 260/552 (47%), Gaps = 45/552 (8%)

Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295
           S S    + + +RD+ND++PRF  S     VSE+  +G  I    A D D G NA  +  
Sbjct: 176 SFSQLIHVEVEVRDINDHSPRFPRSQILVEVSESAAVGTRIPLEVAVDEDVGSNALQSLR 235

Query: 296 MTDKDYTGNVDLPITID-PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354
           + +      V+L    D  ++  +    +LDRE+QA Y L + A DGGDPPRSATA    
Sbjct: 236 LVEPHSFFRVELQTRADGAKNADLLLLQELDRESQANYSLELVAQDGGDPPRSATAVLSV 295

Query: 355 XXXXXXXXXXXFMPGQY-EVELAEDEPPGTPVVTLTATDADEDNRLHYEIT-GGNT--RG 410
                      F  G + EVE++ED P G+ ++ + ATD DE        + GG T    
Sbjct: 296 RVLDANDHSPVFPLGSFIEVEVSEDSPEGSLLLDIDATDPDEGPSGDVVFSFGGRTPPEA 355

Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS--GGRSDTAMVQINITDANNYAPV 468
           +         G +T+ +PLD++Q+  Y L V A D   G R  T  V ++I D N+ APV
Sbjct: 356 QLPFHLDPRSGHLTLTRPLDYEQKETYELDVMAQDQGPGSRVSTCKVIVHILDVNDNAPV 415

Query: 469 FENAPY-----TASVFED---API------------GTTVLVV---SATDSDVGINAQIT 505
               P      TAS +     AP+            G  + ++   +A +S V + + + 
Sbjct: 416 ITIIPLVMAVNTASDYSSSFAAPVSASWEEPGGPQSGVALSLIPEGAAQESLVALVSTLD 475

Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGA---ITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
               S        +  + F + P       + T   LDRE +  Y LT+ A+D G P LS
Sbjct: 476 RDSDSNGQVHCALYGHEHFRLQPAYAGSYLVLTTTPLDRERIPEYNLTLVAQDLGSPPLS 535

Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE-LD 621
                 + V D NDN P+F + +Y  +++E+   G  ++ V A D D+G NG++ Y  L+
Sbjct: 536 TMRPYTVRVADENDNAPLFARPVYEVSVLENNFPGAYLTTVVARDPDLGRNGKVTYRLLE 595

Query: 622 PKDREEGSFV-----IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676
            K+ ++   V     +D  SGV+R  +  DRE++A  ++   A DGG+P Q    +V + 
Sbjct: 596 TKEGQDRDLVSAYVSVDSDSGVLRARRRFDREALAELEVALEARDGGSPSQWGQTVVRLV 655

Query: 677 IEDIND-SP----PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD- 730
           +ED ND +P    P+  +      +    P G  +  ++A D DEGPNA + YS+   D 
Sbjct: 656 VEDQNDHAPEVIFPLLSNGSALVPLPRGVPPGFLVTRVQARDEDEGPNAELTYSLTHSDG 715

Query: 731 DSNSFSLETRQG 742
           D  + +L    G
Sbjct: 716 DPGALALHPHTG 727



 Score =  184 bits (448), Expect = 3e-44
 Identities = 177/616 (28%), Positives = 268/616 (43%), Gaps = 76/616 (12%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           IH ++ V D NDHSP F   Q    V E A+ GT +    A D+D+G NA       L +
Sbjct: 181 IHVEVEVRDINDHSPRFPRSQILVEVSESAAVGTRIPLEVAVDEDVGSNA-------LQS 233

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGA-LLTRASLDREKVARYTVLVKATDQASP 125
              + P             V+   R DG   A LL    LDRE  A Y++ + A D   P
Sbjct: 234 LRLVEPHS--------FFRVELQTRADGAKNADLLLLQELDRESQANYSLELVAQDGGDP 285

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYT-VSVDEDISVTDNPVIAKIKATDADVGAN 184
                S+TA + V ++D ND+ P F   ++  V V ED    +  ++  I ATD D G +
Sbjct: 286 PR---SATAVLSVRVLDANDHSPVFPLGSFIEVEVSEDSP--EGSLLLDIDATDPDEGPS 340

Query: 185 SAIRYAIIGGNT----QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240
             + ++  GG T    Q+ F +D  SG ++L + LDYEQ  +Y L + AQD G  SR +T
Sbjct: 341 GDVVFSF-GGRTPPEAQLPFHLDPRSGHLTLTRPLDYEQKETYELDVMAQDQGPGSRVST 399

Query: 241 TQLLINIRDVNDNAPRF--------------YTSLFQESVSEN------VPIGYSIVRVQ 280
            +++++I DVNDNAP                Y+S F   VS +         G ++  + 
Sbjct: 400 CKVIVHILDVNDNAPVITIIPLVMAVNTASDYSSSFAAPVSASWEEPGGPQSGVALSLIP 459

Query: 281 AYDADEGVNAELTYTMTDKDYTGNVDLPI------TIDPR---SGWVYTSGQLDRETQAK 331
              A E + A ++    D D  G V   +       + P    S  V T+  LDRE   +
Sbjct: 460 EGAAQESLVALVSTLDRDSDSNGQVHCALYGHEHFRLQPAYAGSYLVLTTTPLDRERIPE 519

Query: 332 YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTAT 391
           Y L + A D G PP S                  F    YEV + E+  PG  + T+ A 
Sbjct: 520 YNLTLVAQDLGSPPLSTMRPYTVRVADENDNAPLFARPVYEVSVLENNFPGAYLTTVVAR 579

Query: 392 DAD--EDNRLHY---EITGGNTRGRFS--ITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444
           D D   + ++ Y   E   G  R   S  ++  +  G++   +  D +      + + A 
Sbjct: 580 DPDLGRNGKVTYRLLETKEGQDRDLVSAYVSVDSDSGVLRARRRFDREALAELEVALEAR 639

Query: 445 DSGGRSD--TAMVQINITDANNYA-----PVFENAPYTASVFEDAPIGTTVLVVSATDSD 497
           D G  S     +V++ + D N++A     P+  N      +    P G  V  V A D D
Sbjct: 640 DGGSPSQWGQTVVRLVVEDQNDHAPEVIFPLLSNGSALVPLPRGVPPGFLVTRVQARDED 699

Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG 557
            G NA++TYSL+    +           ++P TG ++  + L    +    L VT +D G
Sbjct: 700 EGPNAELTYSLTHSDGDPGA------LALHPHTGELSLRRQLSPWPIDPLTLVVTVQDNG 753

Query: 558 VPSLSDTTDVEISVVD 573
            PSLS TT + +S+ +
Sbjct: 754 RPSLSCTTTLMLSLAE 769



 Score =  121 bits (292), Expect = 3e-25
 Identities = 89/248 (35%), Positives = 125/248 (50%), Gaps = 16/248 (6%)

Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617
           V S S    VE+ V D+ND+ P F +      + E A VGT +    A D DVG N    
Sbjct: 174 VVSFSQLIHVEVEVRDINDHSPRFPRSQILVEVSESAAVGTRIPLEVAVDEDVGSNALQS 233

Query: 618 YEL-DPKD--REEGSFVIDPASGV-IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673
             L +P    R E     D A    +   + LDRES A + L+ VA DGG PP+S+T ++
Sbjct: 234 LRLVEPHSFFRVELQTRADGAKNADLLLLQELDRESQANYSLELVAQDGGDPPRSATAVL 293

Query: 674 HIKIEDINDSPPVFE-SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732
            +++ D ND  PVF     +   +SE+SP G+ + +I A DPDEGP+  V +S  G    
Sbjct: 294 SVRVLDANDHSPVFPLGSFIEVEVSEDSPEGSLLLDIDATDPDEGPSGDVVFSFGGRTPP 353

Query: 733 NS---FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDV---RVEILVTD 786
            +   F L+ R G     L     LDYE  ++ YEL + A      + V   +V + + D
Sbjct: 354 EAQLPFHLDPRSG----HLTLTRPLDYEQ-KETYELDVMAQDQGPGSRVSTCKVIVHILD 408

Query: 787 VNDNAPVM 794
           VNDNAPV+
Sbjct: 409 VNDNAPVI 416



 Score =  117 bits (281), Expect = 5e-24
 Identities = 168/655 (25%), Positives = 268/655 (40%), Gaps = 73/655 (11%)

Query: 377 EDEPPGTPVVTLTA-TDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP-LDFKQE 434
           E+E PGT +  L+A T AD    +              I      G +TV +  +D +Q 
Sbjct: 102 EEEIPGTVIGVLSAHTRADSPGMVPRNFRLMKQFNTSLIRLSEDDGQLTVGENGIDREQL 161

Query: 435 RRYVLTVSAT-DSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
            +     + T D    S    V++ + D N+++P F  +     V E A +GT + +  A
Sbjct: 162 CQQSQQCTLTFDVVSFSQLIHVEVEVRDINDHSPRFPRSQILVEVSESAAVGTRIPLEVA 221

Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553
            D DVG NA  +  L    S   V    Q      +   +   + LDRE+ + Y L + A
Sbjct: 222 VDEDVGSNALQSLRLVEPHSFFRVEL--QTRADGAKNADLLLLQELDRESQANYSLELVA 279

Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFK-QQLYTANIMEDALVGTSVSQVGATDADVGL 612
           +DGG P  S T  + + V+D ND+ PVF         + ED+  G+ +  + ATD D G 
Sbjct: 280 QDGGDPPRSATAVLSVRVLDANDHSPVFPLGSFIEVEVSEDSPEGSLLLDIDATDPDEGP 339

Query: 613 NGRIHYELDPKDREEGS--FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST 670
           +G + +    +   E    F +DP SG +   + LD E   T++L  +A D G   + ST
Sbjct: 340 SGDVVFSFGGRTPPEAQLPFHLDPRSGHLTLTRPLDYEQKETYELDVMAQDQGPGSRVST 399

Query: 671 VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE--GPNAVVHYSI-- 726
             V + I D+ND+ PV     L   ++  S   ++     +   +E  GP + V  S+  
Sbjct: 400 CKVIVHILDVNDNAPVITIIPLVMAVNTASDYSSSFAAPVSASWEEPGGPQSGVALSLIP 459

Query: 727 KGG---------------DDSNS-----------FSLETRQGSDKAELVTMVDLDYES-P 759
           +G                 DSN            F L+         L T   LD E  P
Sbjct: 460 EGAAQESLVALVSTLDRDSDSNGQVHCALYGHEHFRLQPAYAGSYLVLTT-TPLDRERIP 518

Query: 760 RKKYELVIR-AASPPLWNDVRVEILVTDVNDNAPV----MKDFQIIFNNYKDCFPVGPFG 814
                LV +   SPPL       + V D NDNAP+    + +  ++ NN+   +      
Sbjct: 519 EYNLTLVAQDLGSPPLSTMRPYTVRVADENDNAPLFARPVYEVSVLENNFPGAYLTTVVA 578

Query: 815 RVPAYDADVTDKLQYRIL---SGNNANLI--LLNETTGSMTLSPQLNTNVPKLATMEVSV 869
           R P  D     K+ YR+L    G + +L+   ++  + S  L  +   +   LA +EV++
Sbjct: 579 RDP--DLGRNGKVTYRLLETKEGQDRDLVSAYVSVDSDSGVLRARRRFDREALAELEVAL 636

Query: 870 --TDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCP 927
              DG        Q  VRL+ E+          ND  A + + PLL    +G +A++P P
Sbjct: 637 EARDG-GSPSQWGQTVVRLVVEDQ---------ND-HAPEVIFPLLS---NG-SALVPLP 681

Query: 928 K---ENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERV 979
           +       +  VQ   +  G    +++S    D + G      PH     LR ++
Sbjct: 682 RGVPPGFLVTRVQARDEDEGPNAELTYSLTHSDGDPGALA-LHPHTGELSLRRQL 735



 Score =  106 bits (254), Expect = 1e-20
 Identities = 77/242 (31%), Positives = 120/242 (49%), Gaps = 11/242 (4%)

Query: 116 LVKATDQASPVSDRLSSTATIHVNII--DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK 173
           L + + Q +   D +S +  IHV +   D ND+ P+F      V V E  +V     I  
Sbjct: 161 LCQQSQQCTLTFDVVSFSQLIHVEVEVRDINDHSPRFPRSQILVEVSESAAVGTR--IPL 218

Query: 174 IKATDADVGANSAIRYAIIGGNT----QMQFSIDSL-SGDVSLVKTLDYEQVRSYRLVIR 228
             A D DVG+N+     ++  ++    ++Q   D   + D+ L++ LD E   +Y L + 
Sbjct: 219 EVAVDEDVGSNALQSLRLVEPHSFFRVELQTRADGAKNADLLLLQELDRESQANYSLELV 278

Query: 229 AQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE-SVSENVPIGYSIVRVQAYDADEG 287
           AQDGG P RS T  L + + D ND++P F    F E  VSE+ P G  ++ + A D DEG
Sbjct: 279 AQDGGDPPRSATAVLSVRVLDANDHSPVFPLGSFIEVEVSEDSPEGSLLLDIDATDPDEG 338

Query: 288 VNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRS 347
            + ++ ++   +       LP  +DPRSG +  +  LD E +  Y+L V A D G   R 
Sbjct: 339 PSGDVVFSFGGRT-PPEAQLPFHLDPRSGHLTLTRPLDYEQKETYELDVMAQDQGPGSRV 397

Query: 348 AT 349
           +T
Sbjct: 398 ST 399



 Score =  104 bits (250), Expect = 3e-20
 Identities = 123/487 (25%), Positives = 196/487 (40%), Gaps = 42/487 (8%)

Query: 11  INVLDCNDHSPVFEMQQY-EASVREGASSGTTVLTLKATDQDIGKNAEVEYTI------E 63
           + VLD NDHSPVF +  + E  V E +  G+ +L + ATD D G + +V ++       E
Sbjct: 295 VRVLDANDHSPVFPLGSFIEVEVSEDSPEGSLLLDIDATDPDEGPSGDVVFSFGGRTPPE 354

Query: 64  LVTADTLNPEDAXXXXXXXXXXVQ------DVFRIDGRSGALLTRAS-----LDREKVAR 112
                 L+P              Q      DV   D   G+ ++        LD    A 
Sbjct: 355 AQLPFHLDPRSGHLTLTRPLDYEQKETYELDVMAQDQGPGSRVSTCKVIVHILDVNDNAP 414

Query: 113 YTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIA 172
              ++      +  SD  SS A   V+   +    PQ       +S+  + +  ++ ++A
Sbjct: 415 VITIIPLVMAVNTASDYSSSFAA-PVSASWEEPGGPQSG---VALSLIPEGAAQES-LVA 469

Query: 173 KIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRA 229
            +   D D  +N  +  A+ G      F +        LV T   LD E++  Y L + A
Sbjct: 470 LVSTLDRDSDSNGQVHCALYGHE---HFRLQPAYAGSYLVLTTTPLDRERIPEYNLTLVA 526

Query: 230 QDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN 289
           QD GSP  S      + + D NDNAP F   +++ SV EN   G  +  V A D D G N
Sbjct: 527 QDLGSPPLSTMRPYTVRVADENDNAPLFARPVYEVSVLENNFPGAYLTTVVARDPDLGRN 586

Query: 290 AELTYTMTDKDYTGNVDLP---ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR 346
            ++TY + +     + DL    +++D  SG +    + DRE  A+ ++ + A DGG P +
Sbjct: 587 GKVTYRLLETKEGQDRDLVSAYVSVDSDSGVLRARRRFDREALAELEVALEARDGGSPSQ 646

Query: 347 -SATATXXXXXXXXXXXXXXFMP----GQYEVELAEDEPPGTPVVTLTATDADE--DNRL 399
              T                  P    G   V L    PPG  V  + A D DE  +  L
Sbjct: 647 WGQTVVRLVVEDQNDHAPEVIFPLLSNGSALVPLPRGVPPGFLVTRVQARDEDEGPNAEL 706

Query: 400 HYEIT-GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN 458
            Y +T      G  ++    G   +++ + L         L V+  D+G  S +    + 
Sbjct: 707 TYSLTHSDGDPGALALHPHTGE--LSLRRQLSPWPIDPLTLVVTVQDNGRPSLSCTTTLM 764

Query: 459 ITDANNY 465
           ++ A +Y
Sbjct: 765 LSLAESY 771



 Score = 98.7 bits (235), Expect = 2e-18
 Identities = 78/302 (25%), Positives = 129/302 (42%), Gaps = 9/302 (2%)

Query: 385 VVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444
           +V+    D+D + ++H  + G +   R    +  G  L+    PLD ++   Y LT+ A 
Sbjct: 470 LVSTLDRDSDSNGQVHCALYG-HEHFRLQ-PAYAGSYLVLTTTPLDRERIPEYNLTLVAQ 527

Query: 445 DSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502
           D G    + M    + + D N+ AP+F    Y  SV E+   G  +  V A D D+G N 
Sbjct: 528 DLGSPPLSTMRPYTVRVADENDNAPLFARPVYEVSVLENNFPGAYLTTVVARDPDLGRNG 587

Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
           ++TY L      +          ++  +G +   +  DRE ++   + + ARDGG PS  
Sbjct: 588 KVTYRLLETKEGQDRDLVSAYVSVDSDSGVLRARRRFDREALAELEVALEARDGGSPSQW 647

Query: 563 DTTDVEISVVDVNDNEP-VFKQQLYTANIM----EDALVGTSVSQVGATDADVGLNGRIH 617
             T V + V D ND+ P V    L   + +         G  V++V A D D G N  + 
Sbjct: 648 GQTVVRLVVEDQNDHAPEVIFPLLSNGSALVPLPRGVPPGFLVTRVQARDEDEGPNAELT 707

Query: 618 YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
           Y L   D + G+  + P +G +   + L    +    L     D G P  S T  + + +
Sbjct: 708 YSLTHSDGDPGALALHPHTGELSLRRQLSPWPIDPLTLVVTVQDNGRPSLSCTTTLMLSL 767

Query: 678 ED 679
            +
Sbjct: 768 AE 769



 Score = 84.6 bits (200), Expect = 4e-14
 Identities = 96/343 (27%), Positives = 150/343 (43%), Gaps = 25/343 (7%)

Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM-EDALVGTSVSQVGAT 606
           ++T+      V + SD +    + V  +  EP   Q     +++ E A   + V+ V   
Sbjct: 415 VITIIPLVMAVNTASDYSSSFAAPVSASWEEPGGPQSGVALSLIPEGAAQESLVALVSTL 474

Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPA---SGVIRTNKALDRESVATHDLKAVAIDGG 663
           D D   NG++H  L   +     F + PA   S ++ T   LDRE +  ++L  VA D G
Sbjct: 475 DRDSDSNGQVHCALYGHEH----FRLQPAYAGSYLVLTTTPLDRERIPEYNLTLVAQDLG 530

Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
           +PP S+     +++ D ND+ P+F        + EN+  G  +  + A DPD G N  V 
Sbjct: 531 SPPLSTMRPYTVRVADENDNAPLFARPVYEVSVLENNFPGAYLTTVVARDPDLGRNGKVT 590

Query: 724 YSI---KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWND 777
           Y +   K G D +  S      SD   L      D E+   + E+ + A    SP  W  
Sbjct: 591 YRLLETKEGQDRDLVSAYVSVDSDSGVLRARRRFDREA-LAELEVALEARDGGSPSQWGQ 649

Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDC-FPVG-PFG----RVPAYDAD--VTDKLQY 829
             V ++V D ND+AP +  F ++ N       P G P G    RV A D D     +L Y
Sbjct: 650 TVVRLVVEDQNDHAPEV-IFPLLSNGSALVPLPRGVPPGFLVTRVQARDEDEGPNAELTY 708

Query: 830 RIL-SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            +  S  +   + L+  TG ++L  QL+       T+ V+V D
Sbjct: 709 SLTHSDGDPGALALHPHTGELSLRRQLSPWPIDPLTLVVTVQD 751


>UniRef50_UPI000069E759 Cluster: UPI000069E759 related cluster; n=4;
           Xenopus tropicalis|Rep: UPI000069E759 UniRef100 entry -
           Xenopus tropicalis
          Length = 818

 Score =  220 bits (538), Expect = 4e-55
 Identities = 181/648 (27%), Positives = 293/648 (45%), Gaps = 27/648 (4%)

Query: 90  FRIDGRSGALLTRA-SLDREKVARYTVLVKATDQ--ASPVSDRLSSTATIHVNIIDDNDN 146
           F +D ++G L T A  LDRE +     L +   +  A   S   S  A I + I+D ND+
Sbjct: 65  FHLDKQTGDLYTTAFKLDREHLCPQDTLNQCFVEIDAFVSSQEHSEIAKIKIFILDINDH 124

Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206
            P F+++  T+SV ED +V     I    A+D D G NS + Y +   +       +S  
Sbjct: 125 APFFTDRIITISVQEDTAVGTIFSIDH-SASDPDAGQNSILLYHLNSIDNVFTLGNNSQL 183

Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266
             ++L + LD+E    Y + + A D G P  S +  +++ I DVNDN P F TS     +
Sbjct: 184 LSLTLQQPLDHESKSEYYMDLIASDKGQPPLSGSALIIVQITDVNDNCPVFLTSNMFIIL 243

Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326
             N  +  ++ +++A D D G N+ + Y  +++    +  L   ++  +G +  +  +  
Sbjct: 244 QRNSSVNSTVTQLEAVDEDTGENSIIQYVYSNRVPAESKKL-FHLESMTGILRLAAPIPE 302

Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF----MPGQYEVELAEDEPPG 382
           ++   ++L V A   G  P  AT                F      G+  V + ED P  
Sbjct: 303 DSPNNHKLTVLAIGPGCAPAVATVKLAIQELKRKEPRMEFRVIGAQGEEGVSVKEDVPIN 362

Query: 383 TPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV- 441
           T +  L   D D        I G          +     L+  +  LDF+ E++Y + V 
Sbjct: 363 TIIAILEIKDTDYSILRPVYINGTIPFALKVSENSPDTYLLLTSGILDFELEQKYTIQVL 422

Query: 442 -SATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
            +AT        A + + + D N+ AP F  +    SV E+   G  +L +SA D D G 
Sbjct: 423 GNATFDNLIVYQASLNVKLEDVNDNAPQFPQSVLEVSVEENNSPGAVILELSAFDRDSGS 482

Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560
           N  I YS  +E+  E        F I+   G +T +   DRE  + Y + V A D G P+
Sbjct: 483 NGIIDYSFGAELPME--------FFIDASHGILTASVSFDREQKTSYTVIVLASDHGSPA 534

Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620
            + +  V I+++D NDN P+F    +T ++ E+     +V  +  TDAD GLNG I   +
Sbjct: 535 QNGSCTVIITILDQNDNMPIFLTNEFTFSVPENLSRHGTVGIINVTDADSGLNGEISLSM 594

Query: 621 DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680
                    F +D    +I     LD ES   ++L   A D G PP SSTV V+I + D+
Sbjct: 595 ---LNTTMPFSVD--KNIILLEGYLDYESEYKYELWIEAHDKGNPPLSSTVKVNIMVLDM 649

Query: 681 NDSPPVF---ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
           ND+ P+    +S+     +  ++  G+++ ++ A D D G N  + YS
Sbjct: 650 NDNAPLILLPDSNFSYVLVPPDTLKGSSVTKVHAVDYDAGMNGAIQYS 697



 Score =  181 bits (440), Expect = 3e-43
 Identities = 177/648 (27%), Positives = 285/648 (43%), Gaps = 54/648 (8%)

Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIG--YSIVRVQAYDADEGVNAE 291
           S   S   ++ I I D+ND+AP F   +   SV E+  +G  +SI    A D D G N+ 
Sbjct: 105 SQEHSEIAKIKIFILDINDHAPFFTDRIITISVQEDTAVGTIFSIDH-SASDPDAGQNSI 163

Query: 292 LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGGDPPRSAT 349
           L Y      +  ++D   T+   S  +  + Q  LD E++++Y + + A+D G PP S +
Sbjct: 164 LLY------HLNSIDNVFTLGNNSQLLSLTLQQPLDHESKSEYYMDLIASDKGQPPLSGS 217

Query: 350 ATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITG-- 405
           A               F+     + L  +    + V  L A D D  E++ + Y  +   
Sbjct: 218 ALIIVQITDVNDNCPVFLTSNMFIILQRNSSVNSTVTQLEAVDEDTGENSIIQYVYSNRV 277

Query: 406 -GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANN 464
              ++  F + S  G  ++ +A P+       + LTV A   G     A V++ I +   
Sbjct: 278 PAESKKLFHLESMTG--ILRLAAPIPEDSPNNHKLTVLAIGPGCAPAVATVKLAIQELKR 335

Query: 465 YAPVFENAPYTA------SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518
             P  E     A      SV ED PI T + ++   D+D  I       L     N  + 
Sbjct: 336 KEPRMEFRVIGAQGEEGVSVKEDVPINTIIAILEIKDTDYSI-------LRPVYINGTIP 388

Query: 519 HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578
              +    +P T  + T+ +LD E    Y + V         +     + + + DVNDN 
Sbjct: 389 FALKVSENSPDTYLLLTSGILDFELEQKYTIQVLGNATFDNLIVYQASLNVKLEDVNDNA 448

Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638
           P F Q +   ++ E+   G  + ++ A D D G NG I Y    +   E  F ID + G+
Sbjct: 449 PQFPQSVLEVSVEENNSPGAVILELSAFDRDSGSNGIIDYSFGAELPME--FFIDASHGI 506

Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698
           +  + + DRE   ++ +  +A D G+P Q+ +  V I I D ND+ P+F ++  TF + E
Sbjct: 507 LTASVSFDREQKTSYTVIVLASDHGSPAQNGSCTVIITILDQNDNMPIFLTNEFTFSVPE 566

Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758
           N     T+G I   D D G N  +  S+   + +  FS+      DK  ++    LDYES
Sbjct: 567 NLSRHGTVGIINVTDADSGLNGEISLSML--NTTMPFSV------DKNIILLEGYLDYES 618

Query: 759 PRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVM----KDFQIIFNNYKDCFPVG 811
              KYEL I A    +PPL + V+V I+V D+NDNAP++     +F  +     D     
Sbjct: 619 -EYKYELWIEAHDKGNPPLSSTVKVNIMVLDMNDNAPLILLPDSNFSYVLVP-PDTLKGS 676

Query: 812 PFGRVPA--YDADVTDKLQYRILS--GNNANLILLNETTGSMTLSPQL 855
              +V A  YDA +   +QY      G   +L  ++  TG++TL   +
Sbjct: 677 SVTKVHAVDYDAGMNGAIQYSGFGELGPLGDLFTIDNITGNITLKESI 724



 Score =  177 bits (430), Expect = 5e-42
 Identities = 184/687 (26%), Positives = 299/687 (43%), Gaps = 74/687 (10%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTV-LTLKATDQDIGKNAEVEYTIELVTAD 68
           +I +LD NDH+P F  +    SV+E  + GT   +   A+D D G+N+ + Y +      
Sbjct: 115 KIFILDINDHAPFFTDRIITISVQEDTAVGTIFSIDHSASDPDAGQNSILLYHLN----- 169

Query: 69  TLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LT-RASLDREKVARYTVLVKATDQASPV 126
                            + +VF +   S  L LT +  LD E  + Y + + A+D+  P 
Sbjct: 170 ----------------SIDNVFTLGNNSQLLSLTLQQPLDHESKSEYYMDLIASDKGQPP 213

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
              LS +A I V I D NDN P F      + +  + SV  N  + +++A D D G NS 
Sbjct: 214 ---LSGSALIIVQITDVNDNCPVFLTSNMFIILQRNSSV--NSTVTQLEAVDEDTGENSI 268

Query: 187 IRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
           I+Y     +   ++  F ++S++G + L   +  +   +++L + A   G      T +L
Sbjct: 269 IQYVYSNRVPAESKKLFHLESMTGILRLAAPIPEDSPNNHKLTVLAIGPGCAPAVATVKL 328

Query: 244 LINIRDVNDNAPRFYTSLF----QESVS--ENVPIGYSIVRVQAYDADEGVNAELTYTMT 297
            I  +++    PR    +     +E VS  E+VPI   I  ++  D D        Y++ 
Sbjct: 329 AI--QELKRKEPRMEFRVIGAQGEEGVSVKEDVPINTIIAILEIKDTD--------YSIL 378

Query: 298 DKDY-TGNVDLPITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353
              Y  G +   + +   S   Y   TSG LD E + KY + V      D      A+  
Sbjct: 379 RPVYINGTIPFALKVSENSPDTYLLLTSGILDFELEQKYTIQVLGNATFDNLIVYQASLN 438

Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGR 411
                       F     EV + E+  PG  ++ L+A D D  +   + Y   G      
Sbjct: 439 VKLEDVNDNAPQFPQSVLEVSVEENNSPGAVILELSAFDRDSGSNGIIDYSF-GAELPME 497

Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVF 469
           F I + +G  ++T +   D +Q+  Y + V A+D G   ++ +  V I I D N+  P+F
Sbjct: 498 FFIDASHG--ILTASVSFDREQKTSYTVIVLASDHGSPAQNGSCTVIITILDQNDNMPIF 555

Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
               +T SV E+     TV +++ TD+D G+N +I+ S+ +     +V   D+  ++   
Sbjct: 556 LTNEFTFSVPENLSRHGTVGIINVTDADSGLNGEISLSMLNTTMPFSV---DKNIIL--- 609

Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF---KQQLY 586
                    LD E+   Y L + A D G P LS T  V I V+D+NDN P+         
Sbjct: 610 -----LEGYLDYESEYKYELWIEAHDKGNPPLSSTVKVNIMVLDMNDNAPLILLPDSNFS 664

Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKAL 645
              +  D L G+SV++V A D D G+NG I Y    +    G  F ID  +G I   +++
Sbjct: 665 YVLVPPDTLKGSSVTKVHAVDYDAGMNGAIQYSGFGELGPLGDLFTIDNITGNITLKESI 724

Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVI 672
                  +     A D G P   ST++
Sbjct: 725 IGHHCGLYQFMVKASDQGYPEALSTIV 751



 Score =  138 bits (335), Expect = 2e-30
 Identities = 110/367 (29%), Positives = 173/367 (47%), Gaps = 20/367 (5%)

Query: 99  LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158
           LLT   LD E   +YT+ V      +   + +   A+++V + D NDN PQF +    VS
Sbjct: 403 LLTSGILDFELEQKYTIQVLGN---ATFDNLIVYQASLNVKLEDVNDNAPQFPQSVLEVS 459

Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYE 218
           V+E+ S     VI ++ A D D G+N  I Y+  G    M+F ID+  G ++   + D E
Sbjct: 460 VEENNS--PGAVILELSAFDRDSGSNGIIDYSF-GAELPMEFFIDASHGILTASVSFDRE 516

Query: 219 QVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR 278
           Q  SY +++ A D GSP+++ +  ++I I D NDN P F T+ F  SV EN+    ++  
Sbjct: 517 QKTSYTVIVLASDHGSPAQNGSCTVIITILDQNDNMPIFLTNEFTFSVPENLSRHGTVGI 576

Query: 279 VQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA 338
           +   DAD G+N E++ +M       N  +P ++D     +   G LD E++ KY+L + A
Sbjct: 577 INVTDADSGLNGEISLSML------NTTMPFSVD--KNIILLEGYLDYESEYKYELWIEA 628

Query: 339 TDGGDPPRSATA-TXXXXXXXXXXXXXXFMPGQ--YEVELAEDEPPGTPVVTLTATDADE 395
            D G+PP S+T                  +P      V +  D   G+ V  + A D D 
Sbjct: 629 HDKGNPPLSSTVKVNIMVLDMNDNAPLILLPDSNFSYVLVPPDTLKGSSVTKVHAVDYDA 688

Query: 396 DNRLHYEITGGNTRGRFS--ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG-GRSDT 452
                 + +G    G      T  N  G IT+ + +       Y   V A+D G   + +
Sbjct: 689 GMNGAIQYSGFGELGPLGDLFTIDNITGNITLKESIIGHHCGLYQFMVKASDQGYPEALS 748

Query: 453 AMVQINI 459
            +V+INI
Sbjct: 749 TIVRINI 755


>UniRef50_Q75QY0 Cluster: KIAA0811 protein; n=4; Eukaryota|Rep:
           KIAA0811 protein - Homo sapiens (Human)
          Length = 1123

 Score =  219 bits (536), Expect = 7e-55
 Identities = 143/445 (32%), Positives = 215/445 (48%), Gaps = 20/445 (4%)

Query: 285 DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP 344
           D+G NA++ Y++ D     + +   +ID  +G +     L    QA  +L V A+D G P
Sbjct: 1   DQGANAQVVYSLPD-----SAEGHFSIDATTGVIRLEKPLQVRPQAPLELTVRASDLGTP 55

Query: 345 -PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEI 403
            P S   T              F+  ++ V++ ED PPGT V+ L         +  Y +
Sbjct: 56  IPLSTLGTVTVSVVGLEDYLPVFLNTEHSVQVPEDAPPGTEVLQLATLTRPGAEKTGYRV 115

Query: 404 TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV--SATDSGGRSDTAMVQINITD 461
             GN +GRF + ++   G++ V   LDF+   +Y L++  S   S   SD   V +NITD
Sbjct: 116 VSGNEQGRFRLDART--GILYVNASLDFETSPKYFLSIECSRKSSSSLSDVTTVMVNITD 173

Query: 462 ANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521
            N + P F   PY+  V E+A +G  +L VSATD D  +N+ ITYSL   I    + H  
Sbjct: 174 VNEHRPQFPQDPYSTRVLENALVGDVILTVSATDEDGPLNSDITYSL---IGGNQLGH-- 228

Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581
             F I+P+ G +   K LDRE  S Y L + A D G P L + TD+ I V DVNDN P F
Sbjct: 229 --FTIHPKKGELQVAKALDREQASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPPRF 286

Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641
            Q  Y+  + E++ +G+ V Q+  +D D   NG  +     K     +F + P  G + T
Sbjct: 287 FQLNYSTTVQENSPIGSKVLQLILSDPDSPENGPPYSFRITKGNNGSAFRVTP-DGWLVT 345

Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701
            + L R +   + L+  A D G PP SS   VH+ + + +   P      +   + E+  
Sbjct: 346 AEGLSRRAQEWYQLQIQASDSGIPPLSSLTSVHVHVTEQSHYAPSALPLEIFITVGEDEF 405

Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSI 726
            G  +G+I A D D  P   + YS+
Sbjct: 406 QGGMVGKIHATDRD--PQDTLTYSL 428



 Score =  187 bits (456), Expect = 3e-45
 Identities = 127/374 (33%), Positives = 184/374 (49%), Gaps = 16/374 (4%)

Query: 87  QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146
           Q  FR+D R+G L   ASLD E   +Y + ++ + ++S     LS   T+ VNI D N++
Sbjct: 121 QGRFRLDARTGILYVNASLDFETSPKYFLSIECSRKSS---SSLSDVTTVMVNITDVNEH 177

Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206
            PQF +  Y+  V E+  V D  VI  + ATD D   NS I Y++IGGN    F+I    
Sbjct: 178 RPQFPQDPYSTRVLENALVGD--VILTVSATDEDGPLNSDITYSLIGGNQLGHFTIHPKK 235

Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266
           G++ + K LD EQ  SY L +RA D G P     T + I + DVNDN PRF+   +  +V
Sbjct: 236 GELQVAKALDREQASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPPRFFQLNYSTTV 295

Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326
            EN PIG  ++++   D D   N    Y+   +   GN      + P  GW+ T+  L R
Sbjct: 296 QENSPIGSKVLQLILSDPDSPENGP-PYSF--RITKGNNGSAFRVTP-DGWLVTAEGLSR 351

Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386
             Q  YQL + A+D G PP S+  +               +P +  + + EDE  G  V 
Sbjct: 352 RAQEWYQLQIQASDSGIPPLSSLTSVHVHVTEQSHYAPSALPLEIFITVGEDEFQGGMVG 411

Query: 387 TLTATDADEDNRLHYEITGGNTRGR-FSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445
            + ATD D  + L Y +    T GR FS+ + +G+  I  AQ L       Y   V+ +D
Sbjct: 412 KIHATDRDPQDTLTYSLAEEETLGRHFSVGAPDGK--IIAAQGL---PRGHYSFNVTVSD 466

Query: 446 SGGRSDTAMVQINI 459
            G  + TA V + +
Sbjct: 467 -GTFTTTAGVHVYV 479



 Score =  166 bits (404), Expect = 7e-39
 Identities = 134/472 (28%), Positives = 210/472 (44%), Gaps = 29/472 (6%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F ID  +G +     L     A   + V+A+D  +P+   LS+  T+ V+++   D  P 
Sbjct: 20  FSIDATTGVIRLEKPLQVRPQAPLELTVRASDLGTPIP--LSTLGTVTVSVVGLEDYLPV 77

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209
           F    ++V V ED        + ++ AT    GA     Y ++ GN Q +F +D+ +G +
Sbjct: 78  FLNTEHSVQVPED--APPGTEVLQL-ATLTRPGAEKT-GYRVVSGNEQGRFRLDARTGIL 133

Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269
            +  +LD+E    Y L I      S S S+ T +++NI DVN++ P+F    +   V EN
Sbjct: 134 YVNASLDFETSPKYFLSIECSRKSSSSLSDVTTVMVNITDVNEHRPQFPQDPYSTRVLEN 193

Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329
             +G  I+ V A D D  +N+++TY++   +  G+     TI P+ G +  +  LDRE  
Sbjct: 194 ALVGDVILTVSATDEDGPLNSDITYSLIGGNQLGH----FTIHPKKGELQVAKALDREQA 249

Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389
           + Y L + ATD G PP                    F    Y   + E+ P G+ V+ L 
Sbjct: 250 SSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPPRFFQLNYSTTVQENSPIGSKVLQLI 309

Query: 390 ATDADEDNR---LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446
            +D D         + IT GN    F +T     G +  A+ L  + +  Y L + A+DS
Sbjct: 310 LSDPDSPENGPPYSFRITKGNNGSAFRVTPD---GWLVTAEGLSRRAQEWYQLQIQASDS 366

Query: 447 G--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504
           G    S    V +++T+ ++YAP         +V ED   G  V  + ATD D      +
Sbjct: 367 GIPPLSSLTSVHVHVTEQSHYAPSALPLEIFITVGEDEFQGGMVGKIHATDRDP--QDTL 424

Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556
           TYSL+ E   E +  H   F +    G I   + L R     Y   VT  DG
Sbjct: 425 TYSLAEE---ETLGRH---FSVGAPDGKIIAAQGLPR---GHYSFNVTVSDG 467



 Score =  124 bits (300), Expect = 3e-26
 Identities = 132/486 (27%), Positives = 212/486 (43%), Gaps = 38/486 (7%)

Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556
           D G NAQ+ YSL     + A  H    F I+  TG I   K L     +   LTV A D 
Sbjct: 1   DQGANAQVVYSLP----DSAEGH----FSIDATTGVIRLEKPLQVRPQAPLELTVRASDL 52

Query: 557 GVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615
           G P  LS    V +SVV + D  PVF    ++  + EDA  GT V Q+ AT    G   +
Sbjct: 53  GTPIPLSTLGTVTVSVVGLEDYLPVFLNTEHSVQVPEDAPPGTEVLQL-ATLTRPGAE-K 110

Query: 616 IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675
             Y +     E+G F +D  +G++  N +LD E+   + L        +   S    V +
Sbjct: 111 TGYRV-VSGNEQGRFRLDARTGILYVNASLDFETSPKYFLSIECSRKSSSSLSDVTTVMV 169

Query: 676 KIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735
            I D+N+  P F  D  +  + EN+ +G  I  + A D D   N+ + YS+ GG+    F
Sbjct: 170 NITDVNEHRPQFPQDPYSTRVLENALVGDVILTVSATDEDGPLNSDITYSLIGGNQLGHF 229

Query: 736 SLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792
           ++  ++G    EL     LD E     Y L +RA     PPL  D  + I V DVNDN P
Sbjct: 230 TIHPKKG----ELQVAKALDREQ-ASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPP 284

Query: 793 VMKDFQIIFN-NYKDCFPVG-PFGRVPAYDADVTDK---LQYRILSGNNANLILLNETTG 847
             + FQ+ ++   ++  P+G    ++   D D  +      +RI  GNN +   +    G
Sbjct: 285 --RFFQLNYSTTVQENSPIGSKVLQLILSDPDSPENGPPYSFRITKGNNGSAFRVT-PDG 341

Query: 848 SMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAE 906
            +  +  L+    +   +++  +D G+  + ++  + V  +TE+       + L ++   
Sbjct: 342 WLVTAEGLSRRAQEWYQLQIQASDSGIPPLSSLTSVHVH-VTEQSHYAPSALPL-EIFIT 399

Query: 907 QFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVA-GD 965
                  G  +  + A    P++ +     +++T      L   FS   PD ++  A G 
Sbjct: 400 VGEDEFQGGMVGKIHATDRDPQDTLTYSLAEEET------LGRHFSVGAPDGKIIAAQGL 453

Query: 966 PSPHYS 971
           P  HYS
Sbjct: 454 PRGHYS 459



 Score = 93.9 bits (223), Expect = 6e-17
 Identities = 83/332 (25%), Positives = 144/332 (43%), Gaps = 34/332 (10%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           +N+ D N+H P F    Y   V E A  G  +LT+ ATD+D   N+++ Y+  L+  + L
Sbjct: 169 VNITDVNEHRPQFPQDPYSTRVLENALVGDVILTVSATDEDGPLNSDITYS--LIGGNQL 226

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                              F I  + G L    +LDRE+ + Y++ ++ATD   P    L
Sbjct: 227 GH-----------------FTIHPKKGELQVAKALDREQASSYSLKLRATDSGQP---PL 266

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS-AIRY 189
                I + + D NDN P+F +  Y+ +V E+  +     + ++  +D D   N     +
Sbjct: 267 HEDTDIAIQVADVNDNPPRFFQLNYSTTVQENSPIGSK--VLQLILSDPDSPENGPPYSF 324

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            I  GN    F + +  G +   + L       Y+L I+A D G P  S+ T + +++ +
Sbjct: 325 RITKGNNGSAFRV-TPDGWLVTAEGLSRRAQEWYQLQIQASDSGIPPLSSLTSVHVHVTE 383

Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            +  AP         +V E+   G  + ++ A D D      LTY++ +++  G      
Sbjct: 384 QSHYAPSALPLEIFITVGEDEFQGGMVGKIHATDRDP--QDTLTYSLAEEETLGR---HF 438

Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341
           ++    G +  +  L R     Y   VT +DG
Sbjct: 439 SVGAPDGKIIAAQGLPR---GHYSFNVTVSDG 467



 Score = 36.7 bits (81), Expect = 9.2
 Identities = 24/80 (30%), Positives = 33/80 (41%), Gaps = 7/80 (8%)

Query: 1276 VKNKDFVGCISDFYIDHKFIDL---NSYVA---DNGTLAGCPEKRSRCSSAPCYNGAECS 1329
            V  K F GC+    ++ + +DL      VA   +   L  C      CS   C NG +CS
Sbjct: 678  VSLKGFEGCLDAVVVNEEALDLLAPGKTVAGLLETQALTQCCLHSDYCSQNTCLNGGKCS 737

Query: 1330 DLWDT-YICDCKEGHTGKDC 1348
                  Y+C C    +GK C
Sbjct: 738  WTHGAGYVCKCPPQFSGKHC 757


>UniRef50_Q86N71 Cluster: Cadherin-related protein; n=1; Aplysia
           californica|Rep: Cadherin-related protein - Aplysia
           californica (California sea hare)
          Length = 1172

 Score =  219 bits (535), Expect = 9e-55
 Identities = 190/691 (27%), Positives = 317/691 (45%), Gaps = 59/691 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           IN+ D ND+ P F+  +    + E  + G T     A D+D G+N+   YT+       L
Sbjct: 154 INITDINDNMPTFKPSEITLDIPENNAVGLTKPLPTAMDRDTGQNSVQHYTL-------L 206

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            P  +          + + FR+     +L+  ASLDRE    YT+LV A D  +P    L
Sbjct: 207 EP--SGPFSLDVERRLNNRFRL-----SLVADASLDRELQGHYTLLVVAEDGGAP---SL 256

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           + T T+HVN+ D+NDN P F+++ Y+ SV E   V +  V+ K+ ATD D+G N+ +RY+
Sbjct: 257 TGTMTVHVNVTDENDNSPVFTQEEYSYSVGETERVGE--VVGKLTATDVDLGKNADVRYS 314

Query: 191 IIGGNTQMQ----FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           +I      +    F+++ L+G++++   L+Y+   ++  V+ A+D G  +R    +L ++
Sbjct: 315 LIFSTKDQRGGELFAVEQLTGEITIKAPLEYDAGSTFSAVVEARDRGDIARLTEARLSLS 374

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
           I +V +NAPR   +L Q++V  N       VR+     ++    +LT T  D   +G V 
Sbjct: 375 IVNVGNNAPRLSITL-QKTVRANT------VRISEGARNKTFVGKLTATDNDPGDSGKVQ 427

Query: 307 LPIT--------IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358
                       I P    +  +G LDRE Q    + +  +D G P ++++++       
Sbjct: 428 CHSAHPNFQTNRIGPHEFTIIMNGTLDRERQDTIDVTLVCSDAGAPRKTSSSSFRVVVTD 487

Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT-GGNTRGRFSITSQ 417
                  F    Y V + E+   G  ++ L A D D      +  +        F I S+
Sbjct: 488 VNDNPPRFSQETYVVNVTEENIVGKHILKLRAEDPDYGVNKEFSYSLFPKENDVFGIDSK 547

Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYT 475
           +  G++T     D + ER+  + V+ATD G  S   TA V +NI D N+  P  E     
Sbjct: 548 D--GILTARTTFDHELERKVNVIVTATDRGTPSLVSTATVVVNILDINDNYP--ELTTTE 603

Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSL--SSEISNEAVAHHDQQFVINPQTGAI 533
             V E+      V  +  TD D G NA++ +S+  +S+I+        Q F ++P  G +
Sbjct: 604 LRVPEEGGKMMLVGTLEGTDKDSGRNARLIFSMPPTSDITG-------QMFKVDPD-GRV 655

Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF---KQQLYTANI 590
              + LDRE+ S Y L++  RD GV        V + V DVND+ P F     +  T + 
Sbjct: 656 FAIQNLDRESRSFYSLSIELRDDGVEPKVVYGTVNVIVEDVNDHAPSFHFPTPKNKTVSF 715

Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650
           +        ++++ ATD D G N  I Y +   D+ +  F ++  +G +   + +     
Sbjct: 716 VWSLPTYVPITRLNATDGDAGENQTISYYIFSGDKTD-LFRLEKDTGNLFLRRKVKATDD 774

Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681
               L   A D G   Q S   + + I+  N
Sbjct: 775 QLQTLMVAAHDWGVDQQESQTFIDLVIDITN 805



 Score =  209 bits (511), Expect = 7e-52
 Identities = 181/679 (26%), Positives = 300/679 (44%), Gaps = 43/679 (6%)

Query: 89  VFRIDGRSGALLTRASLDREKVAR---YTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145
           +F I+ RSGAL +   +DRE V       ++       S V+D       +++NI D ND
Sbjct: 103 LFSINRRSGALSSHTMIDRETVCEGMDECIISFDVTVTSDVTD-FFRLVVVNINITDIND 161

Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205
           N P F     T+ + E+ +V     +    A D D G NS   Y ++  +      ++  
Sbjct: 162 NMPTFKPSEITLDIPENNAVGLTKPLPT--AMDRDTGQNSVQHYTLLEPSGPFSLDVERR 219

Query: 206 SGD---VSLVK--TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260
             +   +SLV   +LD E    Y L++ A+DGG+PS + T  + +N+ D NDN+P F   
Sbjct: 220 LNNRFRLSLVADASLDRELQGHYTLLVVAEDGGAPSLTGTMTVHVNVTDENDNSPVFTQE 279

Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM--TDKDYTGNVDLPITIDPRSGWV 318
            +  SV E   +G  + ++ A D D G NA++ Y++  + KD  G  +L   ++  +G +
Sbjct: 280 EYSYSVGETERVGEVVGKLTATDVDLGKNADVRYSLIFSTKDQRGG-EL-FAVEQLTGEI 337

Query: 319 YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE------ 372
                L+ +  + +  +V A D GD  R   A                     +      
Sbjct: 338 TIKAPLEYDAGSTFSAVVEARDRGDIARLTEARLSLSIVNVGNNAPRLSITLQKTVRANT 397

Query: 373 VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ--PLD 430
           V ++E     T V  LTATD D  +    +    +   +   T++ G    T+     LD
Sbjct: 398 VRISEGARNKTFVGKLTATDNDPGDSGKVQCHSAHPNFQ---TNRIGPHEFTIIMNGTLD 454

Query: 431 FKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
            +++    +T+  +D+G   ++ ++  ++ +TD N+  P F    Y  +V E+  +G  +
Sbjct: 455 RERQDTIDVTLVCSDAGAPRKTSSSSFRVVVTDVNDNPPRFSQETYVVNVTEENIVGKHI 514

Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
           L + A D D G+N + +YSL  +         +  F I+ + G +T     D E      
Sbjct: 515 LKLRAEDPDYGVNKEFSYSLFPK--------ENDVFGIDSKDGILTARTTFDHELERKVN 566

Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
           + VTA D G PSL  T  V ++++D+NDN P  +       + E+      V  +  TD 
Sbjct: 567 VIVTATDRGTPSLVSTATVVVNILDINDNYP--ELTTTELRVPEEGGKMMLVGTLEGTDK 624

Query: 609 DVGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
           D G N R+ + + P     G  F +DP  G +   + LDRES + + L     D G  P+
Sbjct: 625 DSGRNARLIFSMPPTSDITGQMFKVDP-DGRVFAIQNLDRESRSFYSLSIELRDDGVEPK 683

Query: 668 SSTVIVHIKIEDINDSPPVFESDC---LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
                V++ +ED+ND  P F        T     + P    I  + A D D G N  + Y
Sbjct: 684 VVYGTVNVIVEDVNDHAPSFHFPTPKNKTVSFVWSLPTYVPITRLNATDGDAGENQTISY 743

Query: 725 SIKGGDDSNSFSLETRQGS 743
            I  GD ++ F LE   G+
Sbjct: 744 YIFSGDKTDLFRLEKDTGN 762



 Score =  208 bits (508), Expect = 2e-51
 Identities = 187/654 (28%), Positives = 273/654 (41%), Gaps = 40/654 (6%)

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           INI D+NDN P F  S     + EN  +G +     A D D G N+   YT+ +     +
Sbjct: 154 INITDINDNMPTFKPSEITLDIPENNAVGLTKPLPTAMDRDTGQNSVQHYTLLEPSGPFS 213

Query: 305 VDLPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
           +D+   ++ R    +     LDRE Q  Y LLV A DGG P  + T T            
Sbjct: 214 LDVERRLNNRFRLSLVADASLDRELQGHYTLLVVAEDGGAPSLTGTMTVHVNVTDENDNS 273

Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDAD----EDNRLHYEITGGNTRGRFSITSQNG 419
             F   +Y   + E E  G  V  LTATD D     D R     +  + RG      +  
Sbjct: 274 PVFTQEEYSYSVGETERVGEVVGKLTATDVDLGKNADVRYSLIFSTKDQRGGELFAVEQL 333

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENA----- 472
            G IT+  PL++     +   V A D G   R   A + ++I +  N AP          
Sbjct: 334 TGEITIKAPLEYDAGSTFSAVVEARDRGDIARLTEARLSLSIVNVGNNAPRLSITLQKTV 393

Query: 473 -PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
              T  + E A   T V  ++ATD+D G         S ++   +   + Q   I P   
Sbjct: 394 RANTVRISEGARNKTFVGKLTATDNDPGD--------SGKVQCHSAHPNFQTNRIGPHEF 445

Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
            I  N  LDRE      +T+   D G P  + ++   + V DVNDN P F Q+ Y  N+ 
Sbjct: 446 TIIMNGTLDRERQDTIDVTLVCSDAGAPRKTSSSSFRVVVTDVNDNPPRFSQETYVVNVT 505

Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA 651
           E+ +VG  + ++ A D D G+N    Y L PK  E   F ID   G++      D E   
Sbjct: 506 EENIVGKHILKLRAEDPDYGVNKEFSYSLFPK--ENDVFGIDSKDGILTARTTFDHELER 563

Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711
             ++   A D GTP   ST  V + I DIND+ P  E       + E       +G +  
Sbjct: 564 KVNVIVTATDRGTPSLVSTATVVVNILDINDNYP--ELTTTELRVPEEGGKMMLVGTLEG 621

Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771
            D D G NA + +S+    D      +         +  + +LD ES R  Y L I    
Sbjct: 622 TDKDSGRNARLIFSMPPTSDITGQMFKV---DPDGRVFAIQNLDRES-RSFYSLSIELRD 677

Query: 772 PPLWNDV---RVEILVTDVNDNAPVMKDFQIIFN---NYKDCFPV-GPFGRVPAYDADVT 824
             +   V    V ++V DVND+AP    F    N   ++    P   P  R+ A D D  
Sbjct: 678 DGVEPKVVYGTVNVIVEDVNDHAPSF-HFPTPKNKTVSFVWSLPTYVPITRLNATDGDAG 736

Query: 825 DK--LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNE 875
           +   + Y I SG+  +L  L + TG++ L  ++     +L T+ V+  D GV++
Sbjct: 737 ENQTISYYIFSGDKTDLFRLEKDTGNLFLRRKVKATDDQLQTLMVAAHDWGVDQ 790



 Score =  128 bits (308), Expect = 3e-27
 Identities = 116/435 (26%), Positives = 192/435 (44%), Gaps = 29/435 (6%)

Query: 454 MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL---SS 510
           +V INITD N+  P F+ +  T  + E+  +G T  + +A D D G N+   Y+L   S 
Sbjct: 151 VVNINITDINDNMPTFKPSEITLDIPENNAVGLTKPLPTAMDRDTGQNSVQHYTLLEPSG 210

Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570
             S +     + +F ++     +  +  LDRE    Y L V A DGG PSL+ T  V ++
Sbjct: 211 PFSLDVERRLNNRFRLS-----LVADASLDRELQGHYTLLVVAEDGGAPSLTGTMTVHVN 265

Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDREEG 628
           V D NDN PVF Q+ Y+ ++ E   VG  V ++ ATD D+G N  + Y L    KD+  G
Sbjct: 266 VTDENDNSPVFTQEEYSYSVGETERVGEVVGKLTATDVDLGKNADVRYSLIFSTKDQRGG 325

Query: 629 S-FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687
             F ++  +G I     L+ ++ +T      A D G   + +   + + I ++ ++ P  
Sbjct: 326 ELFAVEQLTGEITIKAPLEYDAGSTFSAVVEARDRGDIARLTEARLSLSIVNVGNNAPRL 385

Query: 688 ESD------CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH-YSIKGGDDSNSFSLETR 740
                      T  ISE +   T +G++ A D D G +  V  +S      +N      R
Sbjct: 386 SITLQKTVRANTVRISEGARNKTFVGKLTATDNDPGDSGKVQCHSAHPNFQTN------R 439

Query: 741 QGSDKAELVTMVDLDYE-SPRKKYELVIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQ 798
            G  +  ++    LD E        LV   A +P   +     ++VTDVNDN P      
Sbjct: 440 IGPHEFTIIMNGTLDRERQDTIDVTLVCSDAGAPRKTSSSSFRVVVTDVNDNPPRFSQET 499

Query: 799 IIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
            + N  ++        ++ A D D  V  +  Y +    N ++  ++   G +T     +
Sbjct: 500 YVVNVTEENIVGKHILKLRAEDPDYGVNKEFSYSLFPKEN-DVFGIDSKDGILTARTTFD 558

Query: 857 TNVPKLATMEVSVTD 871
             + +   + V+ TD
Sbjct: 559 HELERKVNVIVTATD 573



 Score =  115 bits (276), Expect = 2e-23
 Identities = 103/346 (29%), Positives = 161/346 (46%), Gaps = 38/346 (10%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ V D ND+ P F  + Y  +V E    G  +L L+A D D G N E  Y        +
Sbjct: 482 RVVVTDVNDNPPRFSQETYVVNVTEENIVGKHILKLRAEDPDYGVNKEFSY--------S 533

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
           L P++             DVF ID + G L  R + D E   +  V+V ATD+ +P    
Sbjct: 534 LFPKE------------NDVFGIDSKDGILTARTTFDHELERKVNVIVTATDRGTP---S 578

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           L STAT+ VNI+D NDNYP+ +  T  + V E+       ++  ++ TD D G N+ + +
Sbjct: 579 LVSTATVVVNILDINDNYPELT--TTELRVPEEGG--KMMLVGTLEGTDKDSGRNARLIF 634

Query: 190 AI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
           ++      T   F +D   G V  ++ LD E    Y L I  +D G   +     + + +
Sbjct: 635 SMPPTSDITGQMFKVDP-DGRVFAIQNLDRESRSFYSLSIELRDDGVEPKVVYGTVNVIV 693

Query: 248 RDVNDNAPRF-YTSLFQESVS--ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
            DVND+AP F + +   ++VS   ++P    I R+ A D D G N  ++Y +   D T  
Sbjct: 694 EDVNDHAPSFHFPTPKNKTVSFVWSLPTYVPITRLNATDGDAGENQTISYYIFSGDKT-- 751

Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPPRSAT 349
            DL   ++  +G ++   ++         L+V A D G D   S T
Sbjct: 752 -DL-FRLEKDTGNLFLRRKVKATDDQLQTLMVAAHDWGVDQQESQT 795



 Score =  111 bits (268), Expect = 2e-22
 Identities = 88/291 (30%), Positives = 140/291 (48%), Gaps = 33/291 (11%)

Query: 524 FVINPQTGAITTNKLLDRETM-SGYLLTVTARDGGVPSLSDTTD------VEISVVDVND 576
           F IN ++GA++++ ++DRET+  G    + + D  V   SD TD      V I++ D+ND
Sbjct: 104 FSINRRSGALSSHTMIDRETVCEGMDECIISFD--VTVTSDVTDFFRLVVVNINITDIND 161

Query: 577 NEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPA 635
           N P FK    T +I E+  VG +     A D D G N   HY  L+P     G F +D  
Sbjct: 162 NMPTFKPSEITLDIPENNAVGLTKPLPTAMDRDTGQNSVQHYTLLEP----SGPFSLDVE 217

Query: 636 SGV-------IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688
             +       +  + +LDRE    + L  VA DGG P  + T+ VH+ + D ND+ PVF 
Sbjct: 218 RRLNNRFRLSLVADASLDRELQGHYTLLVVAEDGGAPSLTGTMTVHVNVTDENDNSPVFT 277

Query: 689 SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI----KGGDDSNSFSLETRQGSD 744
            +  ++ + E   +G  +G++ A D D G NA V YS+    K       F++E   G  
Sbjct: 278 QEEYSYSVGETERVGEVVGKLTATDVDLGKNADVRYSLIFSTKDQRGGELFAVEQLTG-- 335

Query: 745 KAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792
             E+     L+Y++    +  V+ A          + R+ + + +V +NAP
Sbjct: 336 --EITIKAPLEYDA-GSTFSAVVEARDRGDIARLTEARLSLSIVNVGNNAP 383



 Score = 82.2 bits (194), Expect = 2e-13
 Identities = 76/268 (28%), Positives = 118/268 (44%), Gaps = 18/268 (6%)

Query: 620 LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST-----VIVH 674
           LDP + E   F I+  SG + ++  +DRE+V     + +     T     T     V+V+
Sbjct: 94  LDPNNAETHLFSINRRSGALSSHTMIDRETVCEGMDECIISFDVTVTSDVTDFFRLVVVN 153

Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734
           I I DIND+ P F+   +T  I EN+ +G T     A D D G N+V HY++       S
Sbjct: 154 INITDINDNMPTFKPSEITLDIPENNAVGLTKPLPTAMDRDTGQNSVQHYTLLEPSGPFS 213

Query: 735 FSLETRQGSD-KAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDN 790
             +E R  +  +  LV    LD E  +  Y L++ A    +P L   + V + VTD NDN
Sbjct: 214 LDVERRLNNRFRLSLVADASLDREL-QGHYTLLVVAEDGGAPSLTGTMTVHVNVTDENDN 272

Query: 791 APVMKDFQIIFNNYKDCFPVGP-FGRVPAYD------ADVTDKLQYRILSGNNANLILLN 843
           +PV    +  + +  +   VG   G++ A D      ADV   L +         L  + 
Sbjct: 273 SPVFTQEEYSY-SVGETERVGEVVGKLTATDVDLGKNADVRYSLIFSTKDQRGGELFAVE 331

Query: 844 ETTGSMTLSPQLNTNVPKLATMEVSVTD 871
           + TG +T+   L  +     +  V   D
Sbjct: 332 QLTGEITIKAPLEYDAGSTFSAVVEARD 359


>UniRef50_O14917 Cluster: Protocadherin-17 precursor; n=23;
           Euteleostomi|Rep: Protocadherin-17 precursor - Homo
           sapiens (Human)
          Length = 1159

 Score =  219 bits (535), Expect = 9e-55
 Identities = 167/591 (28%), Positives = 263/591 (44%), Gaps = 34/591 (5%)

Query: 182 GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
           G + +  Y ++  +      +D+ SG +   + +D E +  +    +       +     
Sbjct: 57  GRSKSGSYRVLENSAPHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDKEIC 116

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
            + + I+D+NDNAP F +   +  +SEN   G       A+D D G N   TY +T  D+
Sbjct: 117 MIKVEIQDINDNAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDH 176

Query: 302 -TGNVDLPITID-PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
               +D+    D  +   +     LDRE Q  + L++TA DGG+PPRSAT          
Sbjct: 177 GLFGLDVKSRGDGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDS 236

Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITG---GNTRGRFSI 414
                 F    Y VEL E+ P GT V+ L ATDADE  +  + Y  +       R  FSI
Sbjct: 237 NDNSPVFEAPSYLVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSI 296

Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENA 472
             + G  LI V   LD+++     + V A D G     A   V + + D N+ AP     
Sbjct: 297 DPKTG--LIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFV 354

Query: 473 PYT-ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE----------AVAHHD 521
                ++ E AP GT + +V  TD D G N Q+   +                 +V    
Sbjct: 355 SVRQGALSEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKL 414

Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581
           ++   N  T  + T++ LDRET   Y +T+ ARDGG P L+ T    I ++D NDN P F
Sbjct: 415 EENYDNFYT--VVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRF 472

Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV----IDPASG 637
            + LY   + E+ + G  +  V A D D+G NG + Y + P    + S      ++P +G
Sbjct: 473 TKGLYVLQVHENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNG 532

Query: 638 VIRTNKALDRESVATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPV-----FESDC 691
            I   ++ + E     + K +A D G P    S   V + + D+ND+ PV      ++D 
Sbjct: 533 AIYALRSFNFEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDT 592

Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
               +  N+ +G  +  +RA D D G +  + Y I  G+D + F ++   G
Sbjct: 593 AELQVPRNAGLGYLVSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSG 643



 Score =  210 bits (513), Expect = 4e-52
 Identities = 187/629 (29%), Positives = 285/629 (45%), Gaps = 51/629 (8%)

Query: 92  IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151
           +D  SG L T+  +DRE + R+    + + +    +D+      I V I D NDN P FS
Sbjct: 77  VDADSGLLYTKQRIDRESLCRHNAKCQLSLEVF-ANDK--EICMIKVEIQDINDNAPSFS 133

Query: 152 EKTYTVSVDEDISV-TDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS-GD- 208
                + + E+ +  T  P+ +   A D D G N    Y +   +  + F +D  S GD 
Sbjct: 134 SDQIEMDISENAAPGTRFPLTS---AHDPDAGENGLRTYLLTRDDHGL-FGLDVKSRGDG 189

Query: 209 -----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263
                + + K LD EQ   + LV+ A DGG P RS T Q+ + + D NDN+P F    + 
Sbjct: 190 TKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYL 249

Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323
             + EN P+G  ++ + A DADEG N E+ Y+ +       V    +IDP++G +   G 
Sbjct: 250 VELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSY-VPDRVRELFSIDPKTGLIRVKGN 308

Query: 324 LDRETQAKYQLLVTATD-GGDP-PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381
           LD E     ++ V A D G +P P     T              F+  + +  L+E  PP
Sbjct: 309 LDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVR-QGALSEAAPP 367

Query: 382 GTPVVTLTATDAD--EDNRLHYEITGGNTRGR------------FSITSQNGRGLITVA- 426
           GT +  +  TD D  ++ +L   + GG   G             F +  +N     TV  
Sbjct: 368 GTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKL-EENYDNFYTVVT 426

Query: 427 -QPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
            +PLD + +  Y +T+ A D G    + T    I I D N+  P F    Y   V E+  
Sbjct: 427 DRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNI 486

Query: 484 IGTTVLVVSATDSDVGINAQITYS-LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
            G  +  V A D D+G N  ++YS L S I + ++  +     +NP  GAI   +  + E
Sbjct: 487 PGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVS---VNPTNGAIYALRSFNFE 543

Query: 543 TMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVF---KQQLYTANIM--EDALV 596
               +   V A+D G P+ L     V ++V+DVNDN PV      Q  TA +    +A +
Sbjct: 544 QTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAELQVPRNAGL 603

Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
           G  VS V A D+D G +GR+ YE+     ++  F IDP+SG IRT      +     +L 
Sbjct: 604 GYLVSTVRALDSDFGESGRLTYEI-VDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELV 662

Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPP 685
               D G P  S+  +  + I  ++ S P
Sbjct: 663 VKVTDHGKPTLSA--VAKLIIRSVSGSLP 689



 Score =  194 bits (474), Expect = 2e-47
 Identities = 167/616 (27%), Positives = 280/616 (45%), Gaps = 41/616 (6%)

Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
           + +D  SG +YT  ++DRE+  ++      +                          F  
Sbjct: 75  LDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDKEICMIKVEIQDINDNAPSFSS 134

Query: 369 GQYEVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSI-TSQNGRGL---- 422
            Q E++++E+  PGT     +A D D  +N L   +   +  G F +     G G     
Sbjct: 135 DQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDGTKFPE 194

Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFE 480
           + + + LD +Q+  + L ++A D G    +A VQIN+   D+N+ +PVFE   Y   + E
Sbjct: 195 LVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYLVELPE 254

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           +AP+GT V+ ++ATD+D G N ++ YS SS + +       + F I+P+TG I     LD
Sbjct: 255 NAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRV----RELFSIDPKTGLIRVKGNLD 310

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP-VFKQQLYTANIMEDALVGTS 599
            E      + V ARD G   +     V + ++D NDN P +    +    + E A  GT 
Sbjct: 311 YEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGALSEAAPPGTV 370

Query: 600 VSQVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGV-------------IRTNKAL 645
           ++ V  TD D G NG++    L       G  +  P   V             + T++ L
Sbjct: 371 IALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDRPL 430

Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
           DRE+   +++  VA DGG+PP +ST    IKI D ND+PP F        + EN+  G  
Sbjct: 431 DRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIPGEY 490

Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRK-KY 763
           +G + A DPD G N  V YSI      + S             +  +   ++E  +  ++
Sbjct: 491 LGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAFEF 550

Query: 764 ELVIRAASPP--LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG------R 815
           +++ + +  P  L ++  V + V DVNDNAPV+     + N+  +       G       
Sbjct: 551 KVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIV-LPTLQNDTAELQVPRNAGLGYLVST 609

Query: 816 VPAYDADVTD--KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-G 872
           V A D+D  +  +L Y I+ GN+ +L  ++ ++G +        +V  +  + V VTD G
Sbjct: 610 VRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVTDHG 669

Query: 873 VNEIKAMMQLSVRLIT 888
              + A+ +L +R ++
Sbjct: 670 KPTLSAVAKLIIRSVS 685



 Score =  180 bits (438), Expect = 5e-43
 Identities = 161/582 (27%), Positives = 256/582 (43%), Gaps = 55/582 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ + D ND++P F   Q E  + E A+ GT      A D D G+N    Y   L+T D 
Sbjct: 119 KVEIQDINDNAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTY---LLTRD- 174

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
                           +    R DG +   L+ + +LDRE+   +T+++ A D   P   
Sbjct: 175 ----------DHGLFGLDVKSRGDGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPR- 223

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             S+T  I+V +ID NDN P F   +Y V + E+  +    V+  + ATDAD G N  + 
Sbjct: 224 --SATVQINVKVIDSNDNSPVFEAPSYLVELPENAPL--GTVVIDLNATDADEGPNGEVL 279

Query: 189 YAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
           Y+    +    +  FSID  +G + +   LDYE+     + ++A+D G        ++ +
Sbjct: 280 YSFSSYVPDRVRELFSIDPKTGLIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTV 339

Query: 246 NIRDVNDNAPRF-YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG- 303
            + D NDNAP   + S+ Q ++SE  P G  I  V+  D D G N +L   +     TG 
Sbjct: 340 KLIDRNDNAPSIGFVSVRQGALSEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGG 399

Query: 304 -------NVDLPITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353
                     +P  ++      Y   T   LDRETQ +Y + + A DGG PP ++T +  
Sbjct: 400 GGGLGGPGGSVPFKLEENYDNFYTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFA 459

Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTR-- 409
                       F  G Y +++ E+  PG  + ++ A D D  ++  + Y I   +    
Sbjct: 460 IKILDENDNPPRFTKGLYVLQVHENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDV 519

Query: 410 GRFSITSQN-GRGLITVAQPLDFKQERRYVLTVSATDSGGRS---DTAMVQINITDANNY 465
             ++  S N   G I   +  +F+Q + +   V A DSG  +     A V++ + D N+ 
Sbjct: 520 SIYTYVSVNPTNGAIYALRSFNFEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDN 579

Query: 466 APV-----FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520
           APV      +N      V  +A +G  V  V A DSD G + ++TY +          + 
Sbjct: 580 APVIVLPTLQNDTAELQVPRNAGLGYLVSTVRALDSDFGESGRLTYEIVD-------GND 632

Query: 521 DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
           D  F I+P +G I T      +      L V   D G P+LS
Sbjct: 633 DHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVTDHGKPTLS 674



 Score =  150 bits (364), Expect = 5e-34
 Identities = 145/548 (26%), Positives = 231/548 (42%), Gaps = 52/548 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + V+D ND+SPVFE   Y   + E A  GT V+ L ATD D G N EV Y+      D  
Sbjct: 231 VKVIDSNDNSPVFEAPSYLVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDR- 289

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                          V+++F ID ++G +  + +LD E+     + V+A D      + +
Sbjct: 290 ---------------VRELFSIDPKTGLIRVKGNLDYEENGMLEIDVQARDLGP---NPI 331

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +   + V +ID NDN P     +       + +     VIA ++ TD D G N  ++  
Sbjct: 332 PAHCKVTVKLIDRNDNAPSIGFVSVRQGALSE-AAPPGTVIALVRVTDRDSGKNGQLQCR 390

Query: 191 IIGGNT------------QMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSP 235
           ++GG               + F ++    +   V T   LD E    Y + I A+DGGSP
Sbjct: 391 VLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDRPLDRETQDEYNVTIVARDGGSP 450

Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295
             ++T    I I D NDN PRF   L+   V EN   G  +  V A D D G N  ++Y+
Sbjct: 451 PLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIPGEYLGSVLAQDPDLGQNGTVSYS 510

Query: 296 MTDKDYTGNVDL--PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR-SATATX 352
           +    + G+V +   ++++P +G +Y     + E    ++  V A D G P    + AT 
Sbjct: 511 IL-PSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAFEFKVLAKDSGAPAHLESNATV 569

Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPP-----GTPVVTLTATDAD--EDNRLHYEITG 405
                         +    + + AE + P     G  V T+ A D+D  E  RL YEI  
Sbjct: 570 RVTVLDVNDNAPVIVLPTLQNDTAELQVPRNAGLGYLVSTVRALDSDFGESGRLTYEIVD 629

Query: 406 GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNY 465
           GN    F I   +G   I    P          L V  TD G  + +A+ ++ I   +  
Sbjct: 630 GNDDHLFEIDPSSGE--IRTLHPFWEDVTPVVELVVKVTDHGKPTLSAVAKLIIRSVSGS 687

Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525
            P  E  P          +   ++V  +T S + + A IT ++  +  N+ +  ++ +  
Sbjct: 688 LP--EGVPRVNGEQHHWDMSLPLIVTLSTISIILLAAMITIAVKCKRENKEIRTYNCRIA 745

Query: 526 --INPQTG 531
              +PQ G
Sbjct: 746 EYSHPQLG 753


>UniRef50_Q9HCL0 Cluster: Protocadherin-18 precursor; n=33;
           Euteleostomi|Rep: Protocadherin-18 precursor - Homo
           sapiens (Human)
          Length = 1128

 Score =  219 bits (534), Expect = 1e-54
 Identities = 183/631 (29%), Positives = 297/631 (47%), Gaps = 50/631 (7%)

Query: 170 VIAKIKATDADVGAN----SAIRY-AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR 224
           VIA++    ADV       S +R+ A+  GN+ +   ++  +G++S+  T+D EQ+    
Sbjct: 36  VIARLSEDVADVLLKLPNPSTVRFRAMQRGNSPL-LVVNEDNGEISIGATIDREQLCQKN 94

Query: 225 LVIRAQDGGSPSRSNTTQLL---INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA 281
           L    +       +   QL    + + D+NDN+P+F  SL    +SE+  +G  I    A
Sbjct: 95  LNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQFSRSLIPIEISESAAVGTRIPLDSA 154

Query: 282 YDADEGVNAELTYTMTDKDYTGNVDLPITID-PRSGWVYTSGQLDRETQAKYQLLVTATD 340
           +D D G N+  TY+++  D+  N+++    D  +   +    +LDRE ++ Y+L +TA+D
Sbjct: 155 FDPDVGENSLHTYSLSANDFF-NIEVRTRTDGAKYAELIVVRELDRELKSSYELQLTASD 213

Query: 341 GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNR 398
            G P RS ++               F    Y ++L E+ P GT ++ L ATD DE  + +
Sbjct: 214 MGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSPVGTLLLDLNATDPDEGANGK 273

Query: 399 LHYEIT---GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA-- 453
           + Y  +          F I S+  RG +T+ + +D++  + Y + V A D G  S  A  
Sbjct: 274 IVYSFSSHVSPKIMETFKIDSE--RGHLTLFKQVDYEITKSYEIDVQAQDLGPNSIPAHC 331

Query: 454 MVQINITDANNYAP------VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507
            + I + D N+  P      +       + +FE  PI T V +V   D D G+N +I   
Sbjct: 332 KIIIKVVDVNDNKPEININLMSPGKEEISYIFEGDPIDTFVALVRVQDKDSGLNGEIVCK 391

Query: 508 LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567
           L      +    ++  ++       I TN  LDRE  S Y LTV A D G PSLS     
Sbjct: 392 LHGHGHFKLQKTYENNYL-------ILTNATLDREKRSEYSLTVIAEDRGTPSLSTVKHF 444

Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627
            + + D+NDN P F++  Y   I E+   G  ++ V ATD D+G NG++ Y +       
Sbjct: 445 TVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLGENGQVTYTILESFILG 504

Query: 628 GSF----VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ--SSTVIVHIKIEDIN 681
            S      IDP++G I   +  D E V+       A DGG+P Q  S+T +V + I D N
Sbjct: 505 SSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGSPKQLVSNTTVV-LTIIDEN 563

Query: 682 DSPPV-----FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736
           D+ PV       ++     I + +  G  +  IRA D D G NA +  +I  G++ N F 
Sbjct: 564 DNVPVVIGPALRNNTAEITIPKGAESGFHVTRIRAIDRDSGVNAELSCAIVAGNEENIFI 623

Query: 737 LETRQGSDKAELVTMVDLDYESPRKKYELVI 767
           ++ R      ++ T V +D   P  ++EL +
Sbjct: 624 IDPR----SCDIHTNVSMD-SVPYTEWELSV 649



 Score =  207 bits (506), Expect = 3e-51
 Identities = 174/611 (28%), Positives = 273/611 (44%), Gaps = 34/611 (5%)

Query: 96  SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155
           +G +   A++DRE++ +  +          +         I V ++D NDN PQFS    
Sbjct: 76  NGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQFSRSLI 135

Query: 156 TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG---NTQMQFSIDSLS-GDVSL 211
            + + E  +V     I    A D DVG NS   Y++      N +++   D     ++ +
Sbjct: 136 PIEISESAAVGTR--IPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKYAELIV 193

Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271
           V+ LD E   SY L + A D G P RS ++ L I+I D NDN+P F    +   + EN P
Sbjct: 194 VRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSP 253

Query: 272 IGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK 331
           +G  ++ + A D DEG N ++ Y+ +    +  +     ID   G +    Q+D E    
Sbjct: 254 VGTLLLDLNATDPDEGANGKIVYSFSSH-VSPKIMETFKIDSERGHLTLFKQVDYEITKS 312

Query: 332 YQLLVTATDGGDPPRSATA-------TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
           Y++ V A D G  P S  A                        PG+ E+    +  P   
Sbjct: 313 YEIDVQAQDLG--PNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEGDPIDT 370

Query: 385 VVTLTATDADEDNRLHYEITGG-NTRGRFSI--TSQNGRGLITVAQPLDFKQERRYVLTV 441
            V L     D+D+ L+ EI    +  G F +  T +N   ++T A  LD ++   Y LTV
Sbjct: 371 FVALVRVQ-DKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTNAT-LDREKRSEYSLTV 428

Query: 442 SATDSGGRSDTAMVQ--INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499
            A D G  S + +    + I D N+  P F+ + Y   + E+   G  +  V+ATD D+G
Sbjct: 429 IAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLG 488

Query: 500 INAQITYS-LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558
            N Q+TY+ L S I   ++  +     I+P  GAI   ++ D E +S     V ARDGG 
Sbjct: 489 ENGQVTYTILESFILGSSITTY---VTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGS 545

Query: 559 PS-LSDTTDVEISVVDVNDNEPV-----FKQQLYTANIMEDALVGTSVSQVGATDADVGL 612
           P  L   T V ++++D NDN PV      +       I + A  G  V+++ A D D G+
Sbjct: 546 PKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAESGFHVTRIRAIDRDSGV 605

Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672
           N  +   +     EE  F+IDP S  I TN ++D       +L  +  D G P   + V+
Sbjct: 606 NAELSCAI-VAGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLHTKVL 664

Query: 673 VHIKIEDINDS 683
           +   I +  +S
Sbjct: 665 LKCMIFEYAES 675



 Score =  189 bits (460), Expect = 1e-45
 Identities = 163/578 (28%), Positives = 261/578 (45%), Gaps = 57/578 (9%)

Query: 8   HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
           H ++ VLD ND+SP F        + E A+ GT +    A D D+G+N+   +T  L   
Sbjct: 115 HIEVEVLDINDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENS--LHTYSLSAN 172

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGA-LLTRASLDREKVARYTVLVKATDQASPV 126
           D  N E                 R DG   A L+    LDRE  + Y + + A+D   P 
Sbjct: 173 DFFNIEVRT--------------RTDGAKYAELIVVRELDRELKSSYELQLTASDMGVP- 217

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
             + S ++ + ++I D NDN P F +++Y + + E+  V    ++  + ATD D GAN  
Sbjct: 218 --QRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSPV--GTLLLDLNATDPDEGANGK 273

Query: 187 IRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
           I Y+    +       F IDS  G ++L K +DYE  +SY + ++AQD G  S     ++
Sbjct: 274 IVYSFSSHVSPKIMETFKIDSERGHLTLFKQVDYEITKSYEIDVQAQDLGPNSIPAHCKI 333

Query: 244 LINIRDVNDNAPRFYTSLF---QESVS---ENVPIGYSIVRVQAYDADEGVNAELTYTMT 297
           +I + DVNDN P    +L    +E +S   E  PI   +  V+  D D G+N E+   + 
Sbjct: 334 IIKVVDVNDNKPEININLMSPGKEEISYIFEGDPIDTFVALVRVQDKDSGLNGEIVCKLH 393

Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357
                G+  L  T +  +  + T+  LDRE +++Y L V A D G P  S          
Sbjct: 394 GH---GHFKLQKTYE-NNYLILTNATLDREKRSEYSLTVIAEDRGTPSLSTVKHFTVQIN 449

Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRG---RF 412
                   F   +YE  ++E+  PG  + T+TATD D  E+ ++ Y I      G     
Sbjct: 450 DINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLGENGQVTYTILESFILGSSITT 509

Query: 413 SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR----SDTAMVQINITDANNYAPV 468
            +T     G I   +  D ++  +    V A D G      S+T +V + I D N+  PV
Sbjct: 510 YVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGSPKQLVSNTTVV-LTIIDENDNVPV 568

Query: 469 -----FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523
                  N     ++ + A  G  V  + A D D G+NA+++ ++          + +  
Sbjct: 569 VIGPALRNNTAEITIPKGAESGFHVTRIRAIDRDSGVNAELSCAI-------VAGNEENI 621

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL 561
           F+I+P++  I TN  +D    + + L+V  +D G P L
Sbjct: 622 FIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQL 659



 Score =  184 bits (449), Expect = 2e-44
 Identities = 152/498 (30%), Positives = 240/498 (48%), Gaps = 36/498 (7%)

Query: 373 VELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSI-TSQNGRGL--ITVAQP 428
           +E++E    GT +   +A D D  +N LH      N      + T  +G     + V + 
Sbjct: 137 IEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKYAELIVVRE 196

Query: 429 LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
           LD + +  Y L ++A+D G   RS +++++I+I+D+N+ +P FE   Y   + E++P+GT
Sbjct: 197 LDRELKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSPVGT 256

Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
            +L ++ATD D G N +I YS SS +S + +    + F I+ + G +T  K +D E    
Sbjct: 257 LLLDLNATDPDEGANGKIVYSFSSHVSPKIM----ETFKIDSERGHLTLFKQVDYEITKS 312

Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT------ANIMEDALVGTSV 600
           Y + V A+D G  S+     + I VVDVNDN+P     L +      + I E   + T V
Sbjct: 313 YEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEGDPIDTFV 372

Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA---SGVIRTNKALDRESVATHDLKA 657
           + V   D D GLNG I  +L       G F +      + +I TN  LDRE  + + L  
Sbjct: 373 ALVRVQDKDSGLNGEIVCKL----HGHGHFKLQKTYENNYLILTNATLDREKRSEYSLTV 428

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
           +A D GTP  S+     ++I DIND+PP F+     F ISEN+  G  I  + A DPD G
Sbjct: 429 IAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLG 488

Query: 718 PNAVVHYSI-KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASP- 772
            N  V Y+I +     +S +           +  +   D+E    +   V+ A    SP 
Sbjct: 489 ENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEV-SQITFVVEARDGGSPK 547

Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-----FGRVPAYDAD--VTD 825
            L ++  V + + D NDN PV+    +  N  +   P G        R+ A D D  V  
Sbjct: 548 QLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAESGFHVTRIRAIDRDSGVNA 607

Query: 826 KLQYRILSGNNANLILLN 843
           +L   I++GN  N+ +++
Sbjct: 608 ELSCAIVAGNEENIFIID 625



 Score =  151 bits (367), Expect = 2e-34
 Identities = 121/414 (29%), Positives = 196/414 (47%), Gaps = 29/414 (7%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           +++ + D N+ +P F  +     + E A +GT + + SA D DVG N+  TYSLS+   N
Sbjct: 116 IEVEVLDINDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSA---N 172

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
           +      +      +   +   + LDRE  S Y L +TA D GVP  S ++ ++IS+ D 
Sbjct: 173 DFFNIEVRTRTDGAKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDS 232

Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY----ELDPKDREEGSF 630
           NDN P F+QQ Y   ++E++ VGT +  + ATD D G NG+I Y     + PK  E  +F
Sbjct: 233 NDNSPAFEQQSYIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIME--TF 290

Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690
            ID   G +   K +D E   ++++   A D G     +   + IK+ D+ND+ P    +
Sbjct: 291 KIDSERGHLTLFKQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININ 350

Query: 691 CLT------FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD 744
            ++       YI E  PI T +  +R  D D G N  +   + G      F L+ +   +
Sbjct: 351 LMSPGKEEISYIFEGDPIDTFVALVRVQDKDSGLNGEIVCKLHG---HGHFKLQ-KTYEN 406

Query: 745 KAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801
              ++T   LD E  R +Y L + A    +P L       + + D+NDN P  +  +  F
Sbjct: 407 NYLILTNATLDREK-RSEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEF 465

Query: 802 NNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGNNANLILLNETTGSMTLSP 853
              ++  P      V A D D+ +  ++ Y IL     + IL +  T  +T+ P
Sbjct: 466 VISENNSPGAYITTVTATDPDLGENGQVTYTILE----SFILGSSITTYVTIDP 515


>UniRef50_Q60H59 Cluster: Protocadherin2-gamma-c6-sCP1; n=37;
           Clupeocephala|Rep: Protocadherin2-gamma-c6-sCP1 - Danio
           rerio (Zebrafish) (Brachydanio rerio)
          Length = 966

 Score =  217 bits (531), Expect = 3e-54
 Identities = 174/607 (28%), Positives = 271/607 (44%), Gaps = 30/607 (4%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIH---VNIIDDNDN 146
           F +D   G L+    +DRE     T+  ++     P+   + +   +H   + I D NDN
Sbjct: 72  FSVDSGKGDLVVNGRIDRE-----TLCGQSASCLMPLQIVIENPLQLHRVEIEIQDINDN 126

Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206
            P F  K   + + E   V      +   A D DV +NS   Y  +  N   + ++ +L 
Sbjct: 127 PPTFHTKDVILKISE--LVAPGTRFSLESAEDLDVSSNSLKTYT-LNNNDFFRLNVKTLK 183

Query: 207 G-----DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261
                 ++ + K LD E+   + L++ A DGG+P +S T+ L I ++D+NDN P+F  + 
Sbjct: 184 NGRKVPELVVEKALDREKQSIHELILTALDGGNPVKSGTSLLQIIVQDINDNEPKFEVAS 243

Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321
           ++ SV E      S+++++A D DEG+N E+ Y         +V     ++  +G +   
Sbjct: 244 YKASVVEKATFDLSVLKIKATDPDEGLNGEIEYLFA-AHTPESVRNVFRVNVETGEIKVI 302

Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381
           G LD ET+  Y   V A D G+P     ++               +       + E+   
Sbjct: 303 GGLDYETKKSYTFDVCAKDKGNPELEGQSSVQIDIIDENDNPPEIILTSLPSPVPENATV 362

Query: 382 GTPVVTLTATDADEDNRLHYEITGGNTRGRFSITS-QNGRGLITVAQPLDFKQERRYVLT 440
           GT V  +   D D  N    E+T         ITS +N   LIT +  LD +    Y + 
Sbjct: 363 GTVVALINVKDLDSGNNGKVELTISTGAPFKIITSFENHYSLITDSF-LDRELNSEYNIE 421

Query: 441 VSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498
           + A D G  S   T  V + + D N+ +PVF  + Y   + E+   G ++  VSATDSD 
Sbjct: 422 ILARDLGVPSLITTKAVNVKVLDVNDNSPVFSQSSYNVYINENNLAGFSLFSVSATDSDQ 481

Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558
             NA +TYS+     N   A     F IN + G I +    D E M    + V A+D G 
Sbjct: 482 DKNAMLTYSVLDLSPNHVPA--SSYFYINSENGTIYSMSSFDYEKMKLISIVVQAKDQGS 539

Query: 559 PSLSDTTDVEISVVDVNDNEP-VFKQQLYTANIMED-----ALVGTSVSQVGATDADVGL 612
           PSLS    V + ++D NDN P V        ++        A  G  V++V A DAD G 
Sbjct: 540 PSLSSNATVHVFILDQNDNAPAVIYPSTSMGSVSHQRMPRFAKAGHLVTKVTAVDADSGH 599

Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672
           N  + Y L  +  +   F ++  +G +RT +A+     ++  L     D G P QS+TV 
Sbjct: 600 NAWLFYRL-AEATDASLFSVNLHTGEVRTKRAVSEHDDSSQRLVLEIKDNGDPIQSTTVT 658

Query: 673 VHIKIED 679
           V I IED
Sbjct: 659 VDILIED 665



 Score =  211 bits (516), Expect = 2e-52
 Identities = 173/628 (27%), Positives = 285/628 (45%), Gaps = 35/628 (5%)

Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDG-GSPS 236
           D+   +  +  I   + +  FS+DS  GD+ +   +D E +  +S   ++  Q    +P 
Sbjct: 52  DISDIAERKLRIASESNRQYFSVDSGKGDLVVNGRIDRETLCGQSASCLMPLQIVIENPL 111

Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
           + +  +  I I+D+NDN P F+T      +SE V  G       A D D   N+  TYT+
Sbjct: 112 QLHRVE--IEIQDINDNPPTFHTKDVILKISELVAPGTRFSLESAEDLDVSSNSLKTYTL 169

Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
            + D+       +    +   +     LDRE Q+ ++L++TA DGG+P +S T+      
Sbjct: 170 NNNDFFRLNVKTLKNGRKVPELVVEKALDREKQSIHELILTALDGGNPVKSGTSLLQIIV 229

Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI---TGGNTRGR 411
                    F    Y+  + E       V+ + ATD DE  +  + Y     T  + R  
Sbjct: 230 QDINDNEPKFEVASYKASVVEKATFDLSVLKIKATDPDEGLNGEIEYLFAAHTPESVRNV 289

Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVF 469
           F +  + G   I V   LD++ ++ Y   V A D G       + VQI+I D N+  P  
Sbjct: 290 FRVNVETGE--IKVIGGLDYETKKSYTFDVCAKDKGNPELEGQSSVQIDIIDENDNPPEI 347

Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
                 + V E+A +GT V +++  D D G N ++  ++S+    + +   +  +     
Sbjct: 348 ILTSLPSPVPENATVGTVVALINVKDLDSGNNGKVELTISTGAPFKIITSFENHY----- 402

Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589
             ++ T+  LDRE  S Y + + ARD GVPSL  T  V + V+DVNDN PVF Q  Y   
Sbjct: 403 --SLITDSFLDRELNSEYNIEILARDLGVPSLITTKAVNVKVLDVNDNSPVFSQSSYNVY 460

Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHY---ELDPKDREEGS-FVIDPASGVIRTNKAL 645
           I E+ L G S+  V ATD+D   N  + Y   +L P      S F I+  +G I +  + 
Sbjct: 461 INENNLAGFSLFSVSATDSDQDKNAMLTYSVLDLSPNHVPASSYFYINSENGTIYSMSSF 520

Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP--VFESDCLTFYISENSP-- 701
           D E +    +   A D G+P  SS   VH+ I D ND+ P  ++ S  +     +  P  
Sbjct: 521 DYEKMKLISIVVQAKDQGSPSLSSNATVHVFILDQNDNAPAVIYPSTSMGSVSHQRMPRF 580

Query: 702 --IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759
              G  + ++ A D D G NA + Y +    D++ FS+    G  + +       +++  
Sbjct: 581 AKAGHLVTKVTAVDADSGHNAWLFYRLAEATDASLFSVNLHTGEVRTKRAVS---EHDDS 637

Query: 760 RKKYELVIRAASPPLWN-DVRVEILVTD 786
            ++  L I+    P+ +  V V+IL+ D
Sbjct: 638 SQRLVLEIKDNGDPIQSTTVTVDILIED 665



 Score =  191 bits (465), Expect = 3e-46
 Identities = 152/536 (28%), Positives = 259/536 (48%), Gaps = 25/536 (4%)

Query: 373 VELAEDEPPGTPVVTLTATDAD-EDNRLHYEITGGNTRGRFSI-TSQNGRGL--ITVAQP 428
           ++++E   PGT     +A D D   N L       N   R ++ T +NGR +  + V + 
Sbjct: 137 LKISELVAPGTRFSLESAEDLDVSSNSLKTYTLNNNDFFRLNVKTLKNGRKVPELVVEKA 196

Query: 429 LDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
           LD +++  + L ++A D G   +S T+++QI + D N+  P FE A Y ASV E A    
Sbjct: 197 LDREKQSIHELILTALDGGNPVKSGTSLLQIIVQDINDNEPKFEVASYKASVVEKATFDL 256

Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
           +VL + ATD D G+N +I Y  ++  + E+V +    F +N +TG I     LD ET   
Sbjct: 257 SVLKIKATDPDEGLNGEIEYLFAAH-TPESVRN---VFRVNVETGEIKVIGGLDYETKKS 312

Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
           Y   V A+D G P L   + V+I ++D NDN P        + + E+A VGT V+ +   
Sbjct: 313 YTFDVCAKDKGNPELEGQSSVQIDIIDENDNPPEIILTSLPSPVPENATVGTVVALINVK 372

Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
           D D G NG++   +      +     +    +I T+  LDRE  + ++++ +A D G P 
Sbjct: 373 DLDSGNNGKVELTISTGAPFKIITSFENHYSLI-TDSFLDRELNSEYNIEILARDLGVPS 431

Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
             +T  V++K+ D+ND+ PVF       YI+EN+  G ++  + A D D+  NA++ YS+
Sbjct: 432 LITTKAVNVKVLDVNDNSPVFSQSSYNVYINENNLAGFSLFSVSATDSDQDKNAMLTYSV 491

Query: 727 KGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEI 782
                ++   S      S+   + +M   DYE   K   +V++A    SP L ++  V +
Sbjct: 492 LDLSPNHVPASSYFYINSENGTIYSMSSFDYEK-MKLISIVVQAKDQGSPSLSSNATVHV 550

Query: 783 LVTDVNDNAPVM----KDFQIIFNNYKDCFPVGP--FGRVPAYDADVTDK--LQYRILSG 834
            + D NDNAP +         + +     F        +V A DAD      L YR+   
Sbjct: 551 FILDQNDNAPAVIYPSTSMGSVSHQRMPRFAKAGHLVTKVTAVDADSGHNAWLFYRLAEA 610

Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEE 890
            +A+L  +N  TG +     ++ +      + + + D  + I++   ++V ++ E+
Sbjct: 611 TDASLFSVNLHTGEVRTKRAVSEHDDSSQRLVLEIKDNGDPIQS-TTVTVDILIED 665



 Score =  176 bits (428), Expect = 8e-42
 Identities = 165/596 (27%), Positives = 252/596 (42%), Gaps = 53/596 (8%)

Query: 4   PFCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
           P  +H+ +I + D ND+ P F  +     + E  + GT      A D D+  N+   YT 
Sbjct: 110 PLQLHRVEIEIQDINDNPPTFHTKDVILKISELVAPGTRFSLESAEDLDVSSNSLKTYT- 168

Query: 63  ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122
                  LN  D            + V         L+   +LDREK + + +++ A D 
Sbjct: 169 -------LNNNDFFRLNVKTLKNGRKV-------PELVVEKALDREKQSIHELILTALDG 214

Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
            +PV    S T+ + + + D NDN P+F   +Y  SV E    T +  + KIKATD D G
Sbjct: 215 GNPVK---SGTSLLQIIVQDINDNEPKFEVASYKASVVE--KATFDLSVLKIKATDPDEG 269

Query: 183 ANSAIRY---AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239
            N  I Y   A    + +  F ++  +G++ ++  LDYE  +SY   + A+D G+P    
Sbjct: 270 LNGEIEYLFAAHTPESVRNVFRVNVETGEIKVIGGLDYETKKSYTFDVCAKDKGNPELEG 329

Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
            + + I+I D NDN P    +     V EN  +G  +  +   D D G N ++  T++  
Sbjct: 330 QSSVQIDIIDENDNPPEIILTSLPSPVPENATVGTVVALINVKDLDSGNNGKVELTIS-- 387

Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
             TG     IT       + T   LDRE  ++Y + + A D G P    T          
Sbjct: 388 --TGAPFKIITSFENHYSLITDSFLDRELNSEYNIEILARDLGVPSLITTKAVNVKVLDV 445

Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGN-----TRGRF 412
                 F    Y V + E+   G  + +++ATD+D+D    L Y +   +         F
Sbjct: 446 NDNSPVFSQSSYNVYINENNLAGFSLFSVSATDSDQDKNAMLTYSVLDLSPNHVPASSYF 505

Query: 413 SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAP-VF 469
            I S+N  G I      D+++ +   + V A D G    S  A V + I D N+ AP V 
Sbjct: 506 YINSEN--GTIYSMSSFDYEKMKLISIVVQAKDQGSPSLSSNATVHVFILDQNDNAPAVI 563

Query: 470 ENAPYTASVFED-----APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524
             +    SV        A  G  V  V+A D+D G NA + Y L       A A     F
Sbjct: 564 YPSTSMGSVSHQRMPRFAKAGHLVTKVTAVDADSGHNAWLFYRL-------AEATDASLF 616

Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580
            +N  TG + T + +     S   L +  +D G P  S T  V+I + D   +EPV
Sbjct: 617 SVNLHTGEVRTKRAVSEHDDSSQRLVLEIKDNGDPIQSTTVTVDILIED-GFHEPV 671


>UniRef50_Q32PS9 Cluster: Pcdh1g18 protein; n=35; Clupeocephala|Rep:
           Pcdh1g18 protein - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 868

 Score =  217 bits (530), Expect = 4e-54
 Identities = 171/602 (28%), Positives = 280/602 (46%), Gaps = 28/602 (4%)

Query: 92  IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151
           +D  +G L+ +  +DRE++         +     + +       + V+I D NDN P F 
Sbjct: 58  LDKENGHLVIKNKIDREELCGEISACSVSFDV--ILENPMELYRVTVDIQDINDNSPAFL 115

Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN---TQMQFSID-SLSG 207
           +      + E + +     +    A D DVG N+  +Y +   +     +Q + D S + 
Sbjct: 116 KSKIEQEISELVLIGARFPLES--AVDPDVGVNALQKYTLQPTDHFKLNVQNAEDGSKNV 173

Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
           ++ L   LD E+   + L++ A DGG P RS T  + I I DVNDNAP F  S ++ S+ 
Sbjct: 174 EIVLHSPLDREKKNHHSLILTAFDGGKPQRSATLHINIIILDVNDNAPVFSQSSYKTSIV 233

Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
           EN P    ++RV A DADE  +    Y    +  T  V    +ID  SG V  +GQ+D E
Sbjct: 234 ENAPKSTVVIRVSATDADESSHGIQYYF---EHATPTVKALFSIDADSGDVKVTGQIDYE 290

Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387
              ++++ V A D G    S+                  M   +   ++ED  PGT +  
Sbjct: 291 KHKQFKIKVKAKDHGGLTDSSEIIIDVIDVNDNKPKITIM--SFSSAVSEDAAPGTVIAM 348

Query: 388 LTATDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446
           +   D D  DN         N+  +   +  N   L+T ++ LD +Q   Y +T++A D 
Sbjct: 349 INVQDLDSGDNSKISCSIDLNSPFKIISSLTNYYNLVTDSE-LDREQTAEYNITITAVDG 407

Query: 447 GG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504
           G    S   ++ + I+D N++AP F    Y A + E+ P  TT+L V A D D G NA++
Sbjct: 408 GNPPLSVKEILNLKISDVNDHAPQFVQESYNAFIAENNPPSTTILTVKAEDMDWGPNAKV 467

Query: 505 TYSL-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD 563
           +Y L  ++++   +A +     IN ++G +   K  D E +  + + V A+DGG P LS 
Sbjct: 468 SYFLIDADLNGAPLASY---ISINSESGVVYAEKSFDYEQLKSFKMQVKAQDGGSPPLSS 524

Query: 564 TTDVEISVVDVNDNEPVFKQQLYT-ANIMED-----ALVGTSVSQVGATDADVGLNGRIH 617
              + I + D NDN P     + T A+++ +     A VG  V++V A D D G N  + 
Sbjct: 525 NVTLNIIIQDQNDNAPQVLYPVQTGASVVAEIVPRAADVGYLVTKVVAVDVDSGQNAWLS 584

Query: 618 YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
           Y+L  K  +   F +   +G IRT + +  +      L  V  D G P +S+ V +++ +
Sbjct: 585 YKLQ-KAADRALFEVGLQNGEIRTVRQVTDKDAVKQKLTVVVEDNGQPSRSAVVSINVAV 643

Query: 678 ED 679
            D
Sbjct: 644 AD 645



 Score =  206 bits (502), Expect = 9e-51
 Identities = 164/582 (28%), Positives = 281/582 (48%), Gaps = 57/582 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           +++ D ND+SP F   + E  + E    G       A D D+G NA  +YT++      L
Sbjct: 102 VDIQDINDNSPAFLKSKIEQEISELVLIGARFPLESAVDPDVGVNALQKYTLQPTDHFKL 161

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           N ++A           +D      ++  ++  + LDREK   +++++ A D   P     
Sbjct: 162 NVQNA-----------ED----GSKNVEIVLHSPLDREKKNHHSLILTAFDGGKP----- 201

Query: 131 SSTATIHVNII--DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             +AT+H+NII  D NDN P FS+ +Y  S+ E  +   + V+ ++ ATDAD  ++    
Sbjct: 202 QRSATLHINIIILDVNDNAPVFSQSSYKTSIVE--NAPKSTVVIRVSATDADESSHGIQY 259

Query: 189 YAIIGGNT-QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
           Y      T +  FSID+ SGDV +   +DYE+ + +++ ++A+D G    +++++++I++
Sbjct: 260 YFEHATPTVKALFSIDADSGDVKVTGQIDYEKHKQFKIKVKAKDHG--GLTDSSEIIIDV 317

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            DVNDN P+     F  +VSE+   G  I  +   D D G N++++ ++   D      +
Sbjct: 318 IDVNDNKPKITIMSFSSAVSEDAAPGTVIAMINVQDLDSGDNSKISCSI---DLNSPFKI 374

Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
             ++      V T  +LDRE  A+Y + +TA DGG+PP S                  F+
Sbjct: 375 ISSLTNYYNLV-TDSELDREQTAEYNITITAVDGGNPPLSVKEILNLKISDVNDHAPQFV 433

Query: 368 PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHY-----EITGGNTRGRFSITSQNGR 420
              Y   +AE+ PP T ++T+ A D D   + ++ Y     ++ G       SI S++  
Sbjct: 434 QESYNAFIAENNPPSTTILTVKAEDMDWGPNAKVSYFLIDADLNGAPLASYISINSES-- 491

Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYAP-VFENAPYTAS 477
           G++   +  D++Q + + + V A D G    ++ V +N  I D N+ AP V       AS
Sbjct: 492 GVVYAEKSFDYEQLKSFKMQVKAQDGGSPPLSSNVTLNIIIQDQNDNAPQVLYPVQTGAS 551

Query: 478 VFED-----APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
           V  +     A +G  V  V A D D G NA ++Y L  + ++ A+      F +  Q G 
Sbjct: 552 VVAEIVPRAADVGYLVTKVVAVDVDSGQNAWLSYKL-QKAADRAL------FEVGLQNGE 604

Query: 533 I-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
           I T  ++ D++ +    LTV   D G PS S    + ++V D
Sbjct: 605 IRTVRQVTDKDAVK-QKLTVVVEDNGQPSRSAVVSINVAVAD 645



 Score =  189 bits (461), Expect = 8e-46
 Identities = 120/376 (31%), Positives = 196/376 (52%), Gaps = 16/376 (4%)

Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480
           I +  PLD +++  + L ++A D G   RS T  + I I D N+ APVF  + Y  S+ E
Sbjct: 175 IVLHSPLDREKKNHHSLILTAFDGGKPQRSATLHINIIILDVNDNAPVFSQSSYKTSIVE 234

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           +AP  T V+ VSATD+D   +    Y   +  + +A+      F I+  +G +     +D
Sbjct: 235 NAPKSTVVIRVSATDADESSHGIQYYFEHATPTVKAL------FSIDADSGDVKVTGQID 288

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
            E    + + V A+D G   L+D++++ I V+DVNDN+P      +++ + EDA  GT +
Sbjct: 289 YEKHKQFKIKVKAKDHG--GLTDSSEIIIDVIDVNDNKPKITIMSFSSAVSEDAAPGTVI 346

Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
           + +   D D G N +I   +D     +    +     ++ T+  LDRE  A +++   A+
Sbjct: 347 AMINVQDLDSGDNSKISCSIDLNSPFKIISSLTNYYNLV-TDSELDREQTAEYNITITAV 405

Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
           DGG PP S   I+++KI D+ND  P F  +    +I+EN+P  TTI  ++A D D GPNA
Sbjct: 406 DGGNPPLSVKEILNLKISDVNDHAPQFVQESYNAFIAENNPPSTTILTVKAEDMDWGPNA 465

Query: 721 VVHYSIKGGD-DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776
            V Y +   D +    +      S+   +      DYE   K +++ ++A    SPPL +
Sbjct: 466 KVSYFLIDADLNGAPLASYISINSESGVVYAEKSFDYEQ-LKSFKMQVKAQDGGSPPLSS 524

Query: 777 DVRVEILVTDVNDNAP 792
           +V + I++ D NDNAP
Sbjct: 525 NVTLNIIIQDQNDNAP 540



 Score =  184 bits (449), Expect = 2e-44
 Identities = 148/473 (31%), Positives = 222/473 (46%), Gaps = 40/473 (8%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           +H  I +LD ND++PVF    Y+ S+ E A   T V+ + ATD D   +  ++Y  E  T
Sbjct: 207 LHINIIILDVNDNAPVFSQSSYKTSIVENAPKSTVVIRVSATDADESSHG-IQYYFEHAT 265

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
                              V+ +F ID  SG +     +D EK  ++ + VKA D     
Sbjct: 266 P-----------------TVKALFSIDADSGDVKVTGQIDYEKHKQFKIKVKAKDHGG-- 306

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
              L+ ++ I +++ID NDN P+ +  +++ +V ED +     VIA I   D D G NS 
Sbjct: 307 ---LTDSSEIIIDVIDVNDNKPKITIMSFSSAVSEDAA--PGTVIAMINVQDLDSGDNSK 361

Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
           I  +I   N+  +  I SL+   +LV    LD EQ   Y + I A DGG+P  S    L 
Sbjct: 362 ISCSI-DLNSPFKI-ISSLTNYYNLVTDSELDREQTAEYNITITAVDGGNPPLSVKEILN 419

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG- 303
           + I DVND+AP+F    +   ++EN P   +I+ V+A D D G NA+++Y + D D  G 
Sbjct: 420 LKISDVNDHAPQFVQESYNAFIAENNPPSTTILTVKAEDMDWGPNAKVSYFLIDADLNGA 479

Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
            +   I+I+  SG VY     D E    +++ V A DGG PP S+  T            
Sbjct: 480 PLASYISINSESGVVYAEKSFDYEQLKSFKMQVKAQDGGSPPLSSNVTLNIIIQDQNDNA 539

Query: 364 XXFM-PGQYEVELAEDEPP-----GTPVVTLTATDADEDNR--LHYEITGGNTRGRFSIT 415
              + P Q    +  +  P     G  V  + A D D      L Y++     R  F + 
Sbjct: 540 PQVLYPVQTGASVVAEIVPRAADVGYLVTKVVAVDVDSGQNAWLSYKLQKAADRALFEVG 599

Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468
            QNG  + TV Q  D K   +  LTV   D+G  S +A+V IN+  A+++  V
Sbjct: 600 LQNGE-IRTVRQVTD-KDAVKQKLTVVVEDNGQPSRSAVVSINVAVADSFPEV 650



 Score =  144 bits (350), Expect = 2e-32
 Identities = 113/345 (32%), Positives = 164/345 (47%), Gaps = 21/345 (6%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           V ++I D N+ +P F  +     + E   IG    + SA D DVG+NA   Y+L      
Sbjct: 100 VTVDIQDINDNSPAFLKSKIEQEISELVLIGARFPLESAVDPDVGVNALQKYTLQP---- 155

Query: 515 EAVAHHDQQFVINPQTGA----ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570
                H +  V N + G+    I  +  LDRE  + + L +TA DGG P  S T  + I 
Sbjct: 156 ---TDHFKLNVQNAEDGSKNVEIVLHSPLDREKKNHHSLILTAFDGGKPQRSATLHINII 212

Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630
           ++DVNDN PVF Q  Y  +I+E+A   T V +V ATDAD   +G  +Y        +  F
Sbjct: 213 ILDVNDNAPVFSQSSYKTSIVENAPKSTVVIRVSATDADESSHGIQYYFEHATPTVKALF 272

Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690
            ID  SG ++    +D E      +K  A D G    SS +I  I + D+ND+ P     
Sbjct: 273 SIDADSGDVKVTGQIDYEKHKQFKIKVKAKDHGGLTDSSEII--IDVIDVNDNKPKITIM 330

Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750
             +  +SE++  GT I  I   D D G N+ +  SI    D NS        ++   LVT
Sbjct: 331 SFSSAVSEDAAPGTVIAMINVQDLDSGDNSKISCSI----DLNSPFKIISSLTNYYNLVT 386

Query: 751 MVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792
             +LD E    +Y + I A    +PPL     + + ++DVND+AP
Sbjct: 387 DSELDREQ-TAEYNITITAVDGGNPPLSVKEILNLKISDVNDHAP 430



 Score = 62.5 bits (145), Expect = 2e-07
 Identities = 56/203 (27%), Positives = 85/203 (41%), Gaps = 6/203 (2%)

Query: 632 IDPASGVIRTNKALDRESVATH-DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690
           +D  +G +     +DRE +       +V+ D           V + I+DIND+ P F   
Sbjct: 58  LDKENGHLVIKNKIDREELCGEISACSVSFDVILENPMELYRVTVDIQDINDNSPAFLKS 117

Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750
            +   ISE   IG       A DPD G NA+  Y+++  D           GS   E+V 
Sbjct: 118 KIEQEISELVLIGARFPLESAVDPDVGVNALQKYTLQPTDHFKLNVQNAEDGSKNVEIVL 177

Query: 751 MVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC 807
              LD E  +  + L++ A     P     + + I++ DVNDNAPV        +  ++ 
Sbjct: 178 HSPLDREK-KNHHSLILTAFDGGKPQRSATLHINIIILDVNDNAPVFSQSSYKTSIVENA 236

Query: 808 FPVGPFGRVPAYDADVTDK-LQY 829
                  RV A DAD +   +QY
Sbjct: 237 PKSTVVIRVSATDADESSHGIQY 259


>UniRef50_UPI00006614A3 Cluster: Homolog of Brachydanio rerio
           "Protocadherin2-gamma-v5-A.; n=3; Clupeocephala|Rep:
           Homolog of Brachydanio rerio "Protocadherin2-gamma-v5-A.
           - Takifugu rubripes
          Length = 715

 Score =  216 bits (527), Expect = 8e-54
 Identities = 171/559 (30%), Positives = 266/559 (47%), Gaps = 47/559 (8%)

Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195
           I V ++D ND+ P F  +   VS++   S           A D DVG N+   Y +    
Sbjct: 122 ITVEVLDINDHAPVFPNQDKHVSLEISESALTGTQFPLQGADDMDVGQNALQNYVLSQNE 181

Query: 196 TQMQFSIDSLSG----DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251
             +     +  G    ++ L K LD E+     L + A DGG+P RS T  + I + D N
Sbjct: 182 NFILKQHANPDGSKYVEMVLQKPLDRERHPHLSLKLIAVDGGTPQRSGTVNIDITVLDAN 241

Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311
           DN P F  S+++ S+ EN  IG ++V V A DAD G+   +TY+++ K   G  ++  TI
Sbjct: 242 DNVPVFNQSVYKASIMENTKIGTNVVTVNATDADSGIYGLITYSLS-KMKGGAAEI-FTI 299

Query: 312 DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371
           D  +G +  SG +D E   KY++ V A D G      T T                   +
Sbjct: 300 DESTGAITVSGPIDYEKDRKYEVRVEARDRG----GLTGTSKVV---------------F 340

Query: 372 EVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ--NGRGLITVAQPL 429
           +V    D PP   V+ +   D+D++ ++   +   + +  F I S   N   LI+  Q  
Sbjct: 341 DVSDVNDNPP---VINVIDADSDKNGQIKCSL---DRKLPFKIESSLTNYYNLIS-DQFF 393

Query: 430 DFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
           D +   +Y +TV+ATDSG    S +  + + I+D N+ AP+FE   Y+A + E+   GT+
Sbjct: 394 DRESVSKYNITVTATDSGTPPLSTSTTLHLIISDVNDNAPLFEKQSYSAYIVENNSPGTS 453

Query: 488 VLVVSATDSDVGINAQITYSL-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
           +  VSA DSD   NA+I+Y L  + IS   ++ +     +N + G I+  +  D E +  
Sbjct: 454 IFTVSARDSDWNQNARISYILEETHISGSPISSY---LSLNSENGVISAARSFDYEQIKE 510

Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM------EDALVGTSV 600
             + V A+DGG P LS    V+I + D NDN P     + T   M        A VG  V
Sbjct: 511 LQIVVKAQDGGSPPLSSNVSVKILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYLV 570

Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
           ++V A D D G N  + Y+L  K  +   F +   +G IRT + +  +      L  +  
Sbjct: 571 TKVVAVDVDSGQNAWLSYKLQ-KATDRALFEVGLQNGEIRTIRQVTDKDAVKQRLSVIVE 629

Query: 661 DGGTPPQSSTVIVHIKIED 679
           D G P +S+TVIV++ + D
Sbjct: 630 DNGQPSRSATVIVNVAVAD 648



 Score =  190 bits (462), Expect = 6e-46
 Identities = 151/519 (29%), Positives = 239/519 (46%), Gaps = 51/519 (9%)

Query: 242 QLLINIRDVNDNAPRFYTSLFQES--VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
           ++ + + D+ND+AP F       S  +SE+   G       A D D G NA   Y ++  
Sbjct: 121 RITVEVLDINDHAPVFPNQDKHVSLEISESALTGTQFPLQGADDMDVGQNALQNYVLSQN 180

Query: 300 DYTGNVDLPITIDPR-SGWVYTSGQ--LDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
           +   N  L    +P  S +V    Q  LDRE      L + A DGG P RS T       
Sbjct: 181 E---NFILKQHANPDGSKYVEMVLQKPLDRERHPHLSLKLIAVDGGTPQRSGTVNIDITV 237

Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSI 414
                    F    Y+  + E+   GT VVT+ ATDAD      + Y ++          
Sbjct: 238 LDANDNVPVFNQSVYKASIMENTKIGTNVVTVNATDADSGIYGLITYSLSKMKGGAAEIF 297

Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPY 474
           T     G ITV+ P+D++++R+Y + V A D GG + T+ V  +++D N+  P       
Sbjct: 298 TIDESTGAITVSGPIDYEKDRKYEVRVEARDRGGLTGTSKVVFDVSDVNDNPP------- 350

Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
                          V++  D+D   N QI  SL  ++  +  +     +        + 
Sbjct: 351 ---------------VINVIDADSDKNGQIKCSLDRKLPFKIESSLTNYY-------NLI 388

Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
           +++  DRE++S Y +TVTA D G P LS +T + + + DVNDN P+F++Q Y+A I+E+ 
Sbjct: 389 SDQFFDRESVSKYNITVTATDSGTPPLSTSTTLHLIISDVNDNAPLFEKQSYSAYIVENN 448

Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV-----IDPASGVIRTNKALDRES 649
             GTS+  V A D+D   N RI Y L+ +    GS +     ++  +GVI   ++ D E 
Sbjct: 449 SPGTSIFTVSARDSDWNQNARISYILE-ETHISGSPISSYLSLNSENGVISAARSFDYEQ 507

Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF------ESDCLTFYISENSPIG 703
           +    +   A DGG+PP SS V V I I+D ND+PP            +   +  ++ +G
Sbjct: 508 IKELQIVVKAQDGGSPPLSSNVSVKILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVG 567

Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
             + ++ A D D G NA + Y ++   D   F +  + G
Sbjct: 568 YLVTKVVAVDVDSGQNAWLSYKLQKATDRALFEVGLQNG 606



 Score =  181 bits (441), Expect = 2e-43
 Identities = 131/376 (34%), Positives = 190/376 (50%), Gaps = 37/376 (9%)

Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480
           + + +PLD ++     L + A D G   RS T  + I + DAN+  PVF  + Y AS+ E
Sbjct: 199 MVLQKPLDRERHPHLSLKLIAVDGGTPQRSGTVNIDITVLDANDNVPVFNQSVYKASIME 258

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           +  IGT V+ V+ATD+D GI   ITYSLS      A     + F I+  TGAIT +  +D
Sbjct: 259 NTKIGTNVVTVNATDADSGIYGLITYSLSKMKGGAA-----EIFTIDESTGAITVSGPID 313

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
            E    Y + V ARD G   L+ T+ V   V DVNDN PV                    
Sbjct: 314 YEKDRKYEVRVEARDRG--GLTGTSKVVFDVSDVNDNPPV-------------------- 351

Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
             +   DAD   NG+I   LD K   +    +     +I +++  DRESV+ +++   A 
Sbjct: 352 --INVIDADSDKNGQIKCSLDRKLPFKIESSLTNYYNLI-SDQFFDRESVSKYNITVTAT 408

Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
           D GTPP S++  +H+ I D+ND+ P+FE    + YI EN+  GT+I  + A D D   NA
Sbjct: 409 DSGTPPLSTSTTLHLIISDVNDNAPLFEKQSYSAYIVENNSPGTSIFTVSARDSDWNQNA 468

Query: 721 VVHYSIKGGDDSNS-FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776
            + Y ++    S S  S      S+   +      DYE   K+ ++V++A    SPPL +
Sbjct: 469 RISYILEETHISGSPISSYLSLNSENGVISAARSFDYEQI-KELQIVVKAQDGGSPPLSS 527

Query: 777 DVRVEILVTDVNDNAP 792
           +V V+IL+ D NDN P
Sbjct: 528 NVSVKILIQDQNDNPP 543



 Score =  173 bits (422), Expect = 4e-41
 Identities = 162/595 (27%), Positives = 264/595 (44%), Gaps = 87/595 (14%)

Query: 4   PFCIHQ-QINVLDCNDHSPVFEMQQYEAS--VREGASSGTTVLTLKATDQDIGKNAEVEY 60
           P  +H+  + VLD NDH+PVF  Q    S  + E A +GT      A D D+G+NA   Y
Sbjct: 116 PLELHRITVEVLDINDHAPVFPNQDKHVSLEISESALTGTQFPLQGADDMDVGQNALQNY 175

Query: 61  TIE----LVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVL 116
            +      +     NP+ +                       ++ +  LDRE+    ++ 
Sbjct: 176 VLSQNENFILKQHANPDGSKYVE-------------------MVLQKPLDRERHPHLSLK 216

Query: 117 VKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKA 176
           + A D  +P   + S T  I + ++D NDN P F++  Y  S+ E+  +  N  +  + A
Sbjct: 217 LIAVDGGTP---QRSGTVNIDITVLDANDNVPVFNQSVYKASIMENTKIGTN--VVTVNA 271

Query: 177 TDADVGANSAIRYAI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS 234
           TDAD G    I Y++  + G     F+ID  +G +++   +DYE+ R Y + + A+D G 
Sbjct: 272 TDADSGIYGLITYSLSKMKGGAAEIFTIDESTGAITVSGPIDYEKDRKYEVRVEARDRG- 330

Query: 235 PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294
              + T++++ ++ DVNDN P                    ++ V   DAD   N ++  
Sbjct: 331 -GLTGTSKVVFDVSDVNDNPP--------------------VINV--IDADSDKNGQIKC 367

Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATDGGDPPRSATATXX 353
           ++ D+     ++  +T    + +   S Q  DRE+ +KY + VTATD G PP S + T  
Sbjct: 368 SL-DRKLPFKIESSLT----NYYNLISDQFFDRESVSKYNITVTATDSGTPPLSTSTTLH 422

Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHY-----EITGG 406
                       F    Y   + E+  PGT + T++A D+D  ++ R+ Y      I+G 
Sbjct: 423 LIISDVNDNAPLFEKQSYSAYIVENNSPGTSIFTVSARDSDWNQNARISYILEETHISGS 482

Query: 407 NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANN 464
                 S+ S+N  G+I+ A+  D++Q +   + V A D G    S    V+I I D N+
Sbjct: 483 PISSYLSLNSEN--GVISAARSFDYEQIKELQIVVKAQDGGSPPLSSNVSVKILIQDQND 540

Query: 465 YAPVFENAPYTAS------VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518
             P       T        V   A +G  V  V A D D G NA ++Y L  + ++ A+ 
Sbjct: 541 NPPQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQNAWLSYKL-QKATDRAL- 598

Query: 519 HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
                F +  Q G I T + +  +      L+V   D G PS S T  V ++V D
Sbjct: 599 -----FEVGLQNGEIRTIRQVTDKDAVKQRLSVIVEDNGQPSRSATVIVNVAVAD 648



 Score =  140 bits (339), Expect = 5e-31
 Identities = 128/474 (27%), Positives = 208/474 (43%), Gaps = 63/474 (13%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           ++  I VLD ND+ PVF    Y+AS+ E    GT V+T+ ATD D G    + Y++  + 
Sbjct: 231 VNIDITVLDANDNVPVFNQSVYKASIMENTKIGTNVVTVNATDADSGIYGLITYSLSKMK 290

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
                                ++F ID  +GA+     +D EK  +Y V V+A D+    
Sbjct: 291 GGAA-----------------EIFTIDESTGAITVSGPIDYEKDRKYEVRVEARDRGG-- 331

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
              L+ T+ +  ++ D                      V DNP +  I   DAD   N  
Sbjct: 332 ---LTGTSKVVFDVSD----------------------VNDNPPV--INVIDADSDKNGQ 364

Query: 187 IRYAIIGGNTQMQFSIDS-LSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
           I+ ++   + ++ F I+S L+   +L+     D E V  Y + + A D G+P  S +T L
Sbjct: 365 IKCSL---DRKLPFKIESSLTNYYNLISDQFFDRESVSKYNITVTATDSGTPPLSTSTTL 421

Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
            + I DVNDNAP F    +   + EN   G SI  V A D+D   NA ++Y + +   +G
Sbjct: 422 HLIISDVNDNAPLFEKQSYSAYIVENNSPGTSIFTVSARDSDWNQNARISYILEETHISG 481

Query: 304 N-VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
           + +   ++++  +G +  +   D E   + Q++V A DGG PP S+  +           
Sbjct: 482 SPISSYLSLNSENGVISAARSFDYEQIKELQIVVKAQDGGSPPLSSNVSVKILIQDQNDN 541

Query: 363 XXXFM-PGQYEVELAEDEPP-----GTPVVTLTATDADEDNR--LHYEITGGNTRGRFSI 414
               + P Q    +  +  P     G  V  + A D D      L Y++     R  F +
Sbjct: 542 PPQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLQKATDRALFEV 601

Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468
             QNG  + T+ Q  D K   +  L+V   D+G  S +A V +N+  A+++  V
Sbjct: 602 GLQNGE-IRTIRQVTD-KDAVKQRLSVIVEDNGQPSRSATVIVNVAVADSFPEV 653



 Score =  139 bits (337), Expect = 9e-31
 Identities = 110/347 (31%), Positives = 163/347 (46%), Gaps = 38/347 (10%)

Query: 455 VQINITDANNYAPVFENAPYTAS--VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512
           + + + D N++APVF N     S  + E A  GT   +  A D DVG NA   Y LS   
Sbjct: 122 ITVEVLDINDHAPVFPNQDKHVSLEISESALTGTQFPLQGADDMDVGQNALQNYVLSQN- 180

Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572
            N  +  H        +   +   K LDRE      L + A DGG P  S T +++I+V+
Sbjct: 181 ENFILKQHANPD--GSKYVEMVLQKPLDRERHPHLSLKLIAVDGGTPQRSGTVNIDITVL 238

Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP-KDREEGSFV 631
           D NDN PVF Q +Y A+IME+  +GT+V  V ATDAD G+ G I Y L   K      F 
Sbjct: 239 DANDNVPVFNQSVYKASIMENTKIGTNVVTVNATDADSGIYGLITYSLSKMKGGAAEIFT 298

Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691
           ID ++G I  +  +D E    ++++  A D G    +S V+    + D+ND+PPV     
Sbjct: 299 IDESTGAITVSGPIDYEKDRKYEVRVEARDRGGLTGTSKVV--FDVSDVNDNPPV----- 351

Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751
                            I   D D   N  +  S+   D    F +E+   ++   L++ 
Sbjct: 352 -----------------INVIDADSDKNGQIKCSL---DRKLPFKIESSL-TNYYNLISD 390

Query: 752 VDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMK 795
              D ES   KY + + A    +PPL     + ++++DVNDNAP+ +
Sbjct: 391 QFFDRESV-SKYNITVTATDSGTPPLSTSTTLHLIISDVNDNAPLFE 436



 Score =  119 bits (287), Expect = 1e-24
 Identities = 90/279 (32%), Positives = 136/279 (48%), Gaps = 16/279 (5%)

Query: 526 INPQTGAITTNKLLDRETMSGYLLTVT-ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584
           +N   G +  N+ +DRE + G +   + + +  + +  +   + + V+D+ND+ PVF  Q
Sbjct: 80  LNTDKGILVVNERIDREQLCGDVTPCSFSIEVILENPLELHRITVEVLDINDHAPVFPNQ 139

Query: 585 --LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP-ASGVIRT 641
               +  I E AL GT     GA D DVG N   +Y L   +        +P  S  +  
Sbjct: 140 DKHVSLEISESALTGTQFPLQGADDMDVGQNALQNYVLSQNENFILKQHANPDGSKYVEM 199

Query: 642 --NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699
              K LDRE      LK +A+DGGTP +S TV + I + D ND+ PVF        I EN
Sbjct: 200 VLQKPLDRERHPHLSLKLIAVDGGTPQRSGTVNIDITVLDANDNVPVFNQSVYKASIMEN 259

Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSI---KGGDDSNSFSLETRQGSDKAELVTMVDLDY 756
           + IGT +  + A D D G   ++ YS+   KGG  +  F+++   G+    +     +DY
Sbjct: 260 TKIGTNVVTVNATDADSGIYGLITYSLSKMKGG-AAEIFTIDESTGA----ITVSGPIDY 314

Query: 757 ESPRKKYELVIRAAS-PPLWNDVRVEILVTDVNDNAPVM 794
           E  R KYE+ + A     L    +V   V+DVNDN PV+
Sbjct: 315 EKDR-KYEVRVEARDRGGLTGTSKVVFDVSDVNDNPPVI 352


>UniRef50_Q24298 Cluster: DE-cadherin precursor; n=5; Neoptera|Rep:
            DE-cadherin precursor - Drosophila melanogaster (Fruit
            fly)
          Length = 1507

 Score =  216 bits (527), Expect = 8e-54
 Identities = 302/1140 (26%), Positives = 476/1140 (41%), Gaps = 105/1140 (9%)

Query: 61   TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYT---VLV 117
            T+E V  D   P+             +  F I+  +G + T  + DR++        V V
Sbjct: 109  TVEAVDPD---PDQVIRYSIVQSPFERPKFFINPSTGVIFTTHTFDRDEPIHEKFVFVTV 165

Query: 118  KATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKAT 177
            +ATD   P  D      T +V I D NDN P F++  Y  S+ E+     + V+  I A+
Sbjct: 166  QATDNGLPPLD---DVCTFNVTIEDINDNAPAFNKARYDESMSENAQ--PDAVVMTISAS 220

Query: 178  DADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237
            D D G NS + Y I+       F ID  SG + L + +D    +SY +++RA +   P  
Sbjct: 221  DFDDGNNSLVEYEILRERDFQYFKIDKESGIIYLKRPIDKRPGQSYAIIVRAYNV-VPDP 279

Query: 238  SNTTQLLINIRDVNDNA--PRFY----TSLFQESVSENVPIGYSIVRVQAYDADEG-VNA 290
                Q+ + IR V  +   P F     T ++ +   +N     + +R  +   D+  V  
Sbjct: 280  PQDAQIEVRIRVVESSIKPPSFVNPIDTPIYLKENLKNFTHPIATLRAVSNMPDKPEVIF 339

Query: 291  ELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350
            EL    T++  + N  +   I      +     LD E    Y L +   +  +     T 
Sbjct: 340  ELNTGRTEQTNSKNTFVFNQIG-NEVTISLGKTLDYEAITDYTLTMIVRNTHE---LGTE 395

Query: 351  TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGN 407
                           +        + E+EPPGTPV+ + A D D    +N + +E+   +
Sbjct: 396  HQIKIQVEDVNDNIPYYTEVKSGTILENEPPGTPVMQVRAFDMDGTSANNIVSFELA--D 453

Query: 408  TRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTA-------MVQIN 458
             R  F+I    G   IT     D ++   Y + V A+D+   S  D         + +I+
Sbjct: 454  NREYFTIDPNTGN--ITALTTFDREERDFYNVKVIASDNSPSSLFDNGEPNRGHQVFRIS 511

Query: 459  ITDANNYAPVFENAPYTAS-VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517
            I D N++ P F+   Y A  + EDA   T V+ V A D D    +QI YS+ S    +A 
Sbjct: 512  IGDKNDHKPHFQQDKYLAERLLEDANTNTEVIEVKAEDEDNA--SQILYSIESGNVGDA- 568

Query: 518  AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577
                  F I  +TG IT N+ LD ET++ Y L V A DG      D T V I + DVNDN
Sbjct: 569  ------FKIGLKTGKITVNQKLDYETITEYELKVRAFDG---IYDDYTTVVIKIEDVNDN 619

Query: 578  EPVFKQQLYTANIMEDALVGTSVSQVGATDADV-GLNGRIHYELDPKDREEGSFVIDPAS 636
             PVFKQ  Y+  I+E+      +  V A D D+   N   H        +   + ID  S
Sbjct: 620  PPVFKQD-YSVTILEETTYDDCILTVEAYDPDIKDRNADQHIVYSIHQNDGNRWTIDN-S 677

Query: 637  GVIRTNKALDRESVATHD-----LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691
            G +R  K LDR+    H      +KA   DG     S+   V + ++DIND+ P   ++ 
Sbjct: 678  GCLRLVKTLDRDPPNGHKNWQVLIKANDEDGVGTTVSTVKEVTVTLKDINDNAPFLINE- 736

Query: 692  LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751
            +  Y  EN   G  + +++A+D D+ P A  +++  G D   +  ++T+   D   L   
Sbjct: 737  MPVYWQENRNPGHVV-QLQANDYDDTPGAG-NFTF-GIDSEATPDIKTKFSMDGDYLHAN 793

Query: 752  VDLDYESPRKKYELVIRAASPPLWNDVRVEIL---VTDVNDNAPVMKDFQIIFNNYKDCF 808
            V  D E+ +K+Y + IR +   +     V IL   + DVNDNA      +I   NYK   
Sbjct: 794  VQFDREA-QKEYFIPIRISDSGVPRQSAVSILHLVIGDVNDNAMSEGSSRIFIYNYKGEA 852

Query: 809  PVGPFGRVPAYDADVTD-KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLA--TM 865
            P    GRV   D D  D + +Y        +   LN +TG +T+          L+    
Sbjct: 853  PETDIGRVFVDDLDDWDLEDKYFEWKDLPHDQFRLNPSTGMITMLVHTAEGEYDLSFVVT 912

Query: 866  EVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIP 925
            E S+    + + A + + VR + EE +  S ++R  ++T E+F+S    F      ++  
Sbjct: 913  EDSMFVPRHSVDAYVTVVVRELPEEAVDKSGSIRFINVTKEEFISVPRDFQSPDALSL-- 970

Query: 926  CPKENIYI-FSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRT 984
              K+ + +  +   +T V+   +           +V  +   SP+Y+P  L   V  ++ 
Sbjct: 971  --KDRLQLSLAKLFNTSVSNVDVFTVLQNENHTLDVRFSAHGSPYYAPEKLNGIVAQNQQ 1028

Query: 985  TLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTC 1044
             L     +Q+L            +N +ECL + KF       N       P Y + S T 
Sbjct: 1029 RLENELDLQML-----------MVNIDECL-IEKFKCEESCTNELHKSSVP-YMIYSNT- 1074

Query: 1045 QCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCE 1104
                 F GVN   +  +  CE          GS      +   +C  C ID  +T   CE
Sbjct: 1075 ---TSFVGVNA-FVQAQCVCEAPLMRRCLNGGSPRYGEND---VCD-C-ID-GFTGPHCE 1124

Query: 1105 LRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNER-----HDFLALEL 1159
            L + +F  S +  +  +   +   + L+   Q   GL++Y G  N        DFLALEL
Sbjct: 1125 LVSVAFYGSGYAFYEPIAACNNTKISLEITPQIDQGLIMYLGPLNFNPLLAISDFLALEL 1184



 Score =  200 bits (489), Expect = 3e-49
 Identities = 182/658 (27%), Positives = 304/658 (46%), Gaps = 57/658 (8%)

Query: 167 DNPVIAKIKATDADVGANSAIRYAIIGGNTQM-QFSIDSLSGDVSLVKTLDYEQVRSYRL 225
           +N  +  ++A D D   +  IRY+I+    +  +F I+  +G +    T D ++    + 
Sbjct: 103 ENTYVLTVEAVDPD--PDQVIRYSIVQSPFERPKFFINPSTGVIFTTHTFDRDEPIHEKF 160

Query: 226 V---IRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY 282
           V   ++A D G P   +     + I D+NDNAP F  + + ES+SEN      ++ + A 
Sbjct: 161 VFVTVQATDNGLPPLDDVCTFNVTIEDINDNAPAFNKARYDESMSENAQPDAVVMTISAS 220

Query: 283 DADEGVNAELTY-TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD- 340
           D D+G N+ + Y  + ++D+         ID  SG +Y    +D+     Y ++V A + 
Sbjct: 221 DFDDGNNSLVEYEILRERDFQ-----YFKIDKESGIIYLKRPIDKRPGQSYAIIVRAYNV 275

Query: 341 GGDPPRSATATXXXXXXXXXXXXXXFM-PGQYEVELAEDEPPGT-PVVTLTATDADEDN- 397
             DPP+ A                 F+ P    + L E+    T P+ TL A     D  
Sbjct: 276 VPDPPQDAQIEVRIRVVESSIKPPSFVNPIDTPIYLKENLKNFTHPIATLRAVSNMPDKP 335

Query: 398 RLHYEITGG-----NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT 452
            + +E+  G     N++  F          I++ + LD++    Y LT+   ++      
Sbjct: 336 EVIFELNTGRTEQTNSKNTFVFNQIGNEVTISLGKTLDYEAITDYTLTMIVRNTHELGTE 395

Query: 453 AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512
             ++I + D N+  P +     + ++ E+ P GT V+ V A D D G +A       + I
Sbjct: 396 HQIKIQVEDVNDNIPYYTEVK-SGTILENEPPGTPVMQVRAFDMD-GTSA-------NNI 446

Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD------ 566
            +  +A + + F I+P TG IT     DRE    Y + V A D    SL D  +      
Sbjct: 447 VSFELADNREYFTIDPNTGNITALTTFDREERDFYNVKVIASDNSPSSLFDNGEPNRGHQ 506

Query: 567 -VEISVVDVNDNEPVFKQQLYTA-NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624
              IS+ D ND++P F+Q  Y A  ++EDA   T V +V A D D     +I Y ++  +
Sbjct: 507 VFRISIGDKNDHKPHFQQDKYLAERLLEDANTNTEVIEVKAEDEDNA--SQILYSIESGN 564

Query: 625 REEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP 684
             + +F I   +G I  N+ LD E++  ++LK  A DG     ++ V   IKIED+ND+P
Sbjct: 565 VGD-AFKIGLKTGKITVNQKLDYETITEYELKVRAFDGIYDDYTTVV---IKIEDVNDNP 620

Query: 685 PVFESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAVVH--YSIKGGDDSNSFSLETRQ 741
           PVF+ D  +  I E +     I  + A+DPD +  NA  H  YSI   +D N ++++   
Sbjct: 621 PVFKQD-YSVTILEETTYDDCILTVEAYDPDIKDRNADQHIVYSIH-QNDGNRWTID--- 675

Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRA-----ASPPLWNDVRVEILVTDVNDNAPVM 794
            S    LV  +D D  +  K ++++I+A         +     V + + D+NDNAP +
Sbjct: 676 NSGCLRLVKTLDRDPPNGHKNWQVLIKANDEDGVGTTVSTVKEVTVTLKDINDNAPFL 733



 Score =  189 bits (461), Expect = 8e-46
 Identities = 189/735 (25%), Positives = 318/735 (43%), Gaps = 79/735 (10%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + + D ND++P F   +Y+ S+ E A     V+T+ A+D D G N+ VEY I       L
Sbjct: 183 VTIEDINDNAPAFNKARYDESMSENAQPDAVVMTISASDFDDGNNSLVEYEI-------L 235

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQA-SPVSDR 129
              D               F+ID  SG +  +  +D+     Y ++V+A +    P  D 
Sbjct: 236 RERDF------------QYFKIDKESGIIYLKRPIDKRPGQSYAIIVRAYNVVPDPPQD- 282

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYT-VSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             +   + + +++ +   P F     T + + E++    +P IA ++A  +++     + 
Sbjct: 283 --AQIEVRIRVVESSIKPPSFVNPIDTPIYLKENLKNFTHP-IATLRAV-SNMPDKPEVI 338

Query: 189 YAIIGGNTQMQ-----FSIDSLSGDV--SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
           + +  G T+       F  + +  +V  SL KTLDYE +  Y L +  ++  +       
Sbjct: 339 FELNTGRTEQTNSKNTFVFNQIGNEVTISLGKTLDYEAITDYTLTMIVRN--THELGTEH 396

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTD-K 299
           Q+ I + DVNDN P +YT +   ++ EN P G  +++V+A+D D    N  +++ + D +
Sbjct: 397 QIKIQVEDVNDNIP-YYTEVKSGTILENEPPGTPVMQVRAFDMDGTSANNIVSFELADNR 455

Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG--------GDPPRSATAT 351
           +Y        TIDP +G +      DRE +  Y + V A+D         G+P R     
Sbjct: 456 EY-------FTIDPNTGNITALTTFDREERDFYNVKVIASDNSPSSLFDNGEPNRGHQV- 507

Query: 352 XXXXXXXXXXXXXXFMPGQYEVE-LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG 410
                         F   +Y  E L ED    T V+ + A D D  +++ Y I  GN   
Sbjct: 508 FRISIGDKNDHKPHFQQDKYLAERLLEDANTNTEVIEVKAEDEDNASQILYSIESGNVGD 567

Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFE 470
            F I  + G+  ITV Q LD++    Y L V A D G   D   V I I D N+  PVF+
Sbjct: 568 AFKIGLKTGK--ITVNQKLDYETITEYELKVRAFD-GIYDDYTTVVIKIEDVNDNPPVFK 624

Query: 471 NAPYTASVFEDAPIGTTVLVVSATDSDV---GINAQITYSLSSEISNEAVAHHDQQFVIN 527
              Y+ ++ E+      +L V A D D+     +  I YS+     N        ++ I+
Sbjct: 625 Q-DYSVTILEETTYDDCILTVEAYDPDIKDRNADQHIVYSIHQNDGN--------RWTID 675

Query: 528 PQTGAITTNKLLDRETMSGY-----LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582
             +G +   K LDR+  +G+     L+     DG   ++S   +V +++ D+NDN P   
Sbjct: 676 -NSGCLRLVKTLDRDPPNGHKNWQVLIKANDEDGVGTTVSTVKEVTVTLKDINDNAPFLI 734

Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLN-GRIHYELDPKDREEGSFVIDPASGVIRT 641
            ++      E+   G  V Q+ A D D     G   + +D +   +           +  
Sbjct: 735 NEM-PVYWQENRNPG-HVVQLQANDYDDTPGAGNFTFGIDSEATPDIKTKFSMDGDYLHA 792

Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701
           N   DRE+   + +     D G P QS+  I+H+ I D+ND+     S  +  Y  +   
Sbjct: 793 NVQFDREAQKEYFIPIRISDSGVPRQSAVSILHLVIGDVNDNAMSEGSSRIFIYNYKGEA 852

Query: 702 IGTTIGEIRAHDPDE 716
             T IG +   D D+
Sbjct: 853 PETDIGRVFVDDLDD 867



 Score =  121 bits (291), Expect = 3e-25
 Identities = 112/401 (27%), Positives = 179/401 (44%), Gaps = 26/401 (6%)

Query: 463 NNYAPVFEN-APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521
           +N  P F+N A Y   V E+ P  T VL V A D D   +  I YS+             
Sbjct: 81  DNRKPAFKNCAGYAPKVKEEQPENTYVLTVEAVDPDP--DQVIRYSIVQS------PFER 132

Query: 522 QQFVINPQTGAITTNKLLDRETM---SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578
            +F INP TG I T    DR+         +TV A D G+P L D     +++ D+NDN 
Sbjct: 133 PKFFINPSTGVIFTTHTFDRDEPIHEKFVFVTVQATDNGLPPLDDVCTFNVTIEDINDNA 192

Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638
           P F +  Y  ++ E+A     V  + A+D D G N  + YE+  ++R+   F ID  SG+
Sbjct: 193 PAFNKARYDESMSENAQPDAVVMTISASDFDDGNNSLVEYEI-LRERDFQYFKIDKESGI 251

Query: 639 IRTNKALDRESVATHDLKAVAID-GGTPPQSSTVIVHIKIEDINDSPPVFESDCLT-FYI 696
           I   + +D+    ++ +   A +    PPQ + + V I++ + +  PP F +   T  Y+
Sbjct: 252 IYLKRPIDKRPGQSYAIIVRAYNVVPDPPQDAQIEVRIRVVESSIKPPSFVNPIDTPIYL 311

Query: 697 SENSPIGT-TIGEIRA--HDPDEGPNAVVHYSIKGGDDSNS-FSLETRQGSDKAELVTMV 752
            EN    T  I  +RA  + PD+ P  +   +    + +NS  +    Q  ++  +    
Sbjct: 312 KENLKNFTHPIATLRAVSNMPDK-PEVIFELNTGRTEQTNSKNTFVFNQIGNEVTISLGK 370

Query: 753 DLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQ--IIFNNYKDCFPV 810
            LDYE+       +I   +  L  + +++I V DVNDN P   + +   I  N     P 
Sbjct: 371 TLDYEAITDYTLTMIVRNTHELGTEHQIKIQVEDVNDNIPYYTEVKSGTILENEP---PG 427

Query: 811 GPFGRVPAYDADVTDKLQYRILS-GNNANLILLNETTGSMT 850
            P  +V A+D D T           +N     ++  TG++T
Sbjct: 428 TPVMQVRAFDMDGTSANNIVSFELADNREYFTIDPNTGNIT 468



 Score =  114 bits (274), Expect = 4e-23
 Identities = 130/527 (24%), Positives = 226/527 (42%), Gaps = 41/527 (7%)

Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGN-TRGRFSITSQNGRGLITVAQPL 429
           Y  ++ E++P  T V+T+ A D D D  + Y I      R +F I    G    T     
Sbjct: 93  YAPKVKEEQPENTYVLTVEAVDPDPDQVIRYSIVQSPFERPKFFINPSTGVIFTTHTFDR 152

Query: 430 DFKQERRYV-LTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
           D     ++V +TV ATD+G     D     + I D N+ AP F  A Y  S+ E+A    
Sbjct: 153 DEPIHEKFVFVTVQATDNGLPPLDDVCTFNVTIEDINDNAPAFNKARYDESMSENAQPDA 212

Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
            V+ +SA+D D G N+ + Y +  E          Q F I+ ++G I   + +D+     
Sbjct: 213 VVMTISASDFDDGNNSLVEYEILRE-------RDFQYFKIDKESGIIYLKRPIDKRPGQS 265

Query: 547 YLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS--VSQV 603
           Y + V A +    P      +V I VV+ +   P F   + T   +++ L   +  ++ +
Sbjct: 266 YAIIVRAYNVVPDPPQDAQIEVRIRVVESSIKPPSFVNPIDTPIYLKENLKNFTHPIATL 325

Query: 604 GATDADVGLNGRIHYELDPKDREE----GSFVIDPASG--VIRTNKALDRESVATHDLKA 657
            A  +++     + +EL+    E+     +FV +       I   K LD E++  + L  
Sbjct: 326 RAV-SNMPDKPEVIFELNTGRTEQTNSKNTFVFNQIGNEVTISLGKTLDYEAITDYTLTM 384

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
           +     T    +   + I++ED+ND+ P + ++  +  I EN P GT + ++RA D D G
Sbjct: 385 IV--RNTHELGTEHQIKIQVEDVNDNIPYY-TEVKSGTILENEPPGTPVMQVRAFDMD-G 440

Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA--SP--- 772
            +A    S +  D+   F+++   G+    +  +   D E  R  Y + + A+  SP   
Sbjct: 441 TSANNIVSFELADNREYFTIDPNTGN----ITALTTFDREE-RDFYNVKVIASDNSPSSL 495

Query: 773 -----PLWNDVRVEILVTDVNDNAP-VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK 826
                P        I + D ND+ P   +D  +     +D         V A D D   +
Sbjct: 496 FDNGEPNRGHQVFRISIGDKNDHKPHFQQDKYLAERLLEDANTNTEVIEVKAEDEDNASQ 555

Query: 827 LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGV 873
           + Y I SGN  +   +   TG +T++ +L+        ++V   DG+
Sbjct: 556 ILYSIESGNVGDAFKIGLKTGKITVNQKLDYETITEYELKVRAFDGI 602


>UniRef50_UPI000065EB3B Cluster: Homolog of Brachydanio rerio
           "Paraxial protocadherin.; n=1; Takifugu rubripes|Rep:
           Homolog of Brachydanio rerio "Paraxial protocadherin. -
           Takifugu rubripes
          Length = 980

 Score =  215 bits (526), Expect = 1e-53
 Identities = 172/631 (27%), Positives = 289/631 (45%), Gaps = 40/631 (6%)

Query: 91  RIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQF 150
           R+    G L     +DRE++ R+T     T      S        + V I D NDN P+F
Sbjct: 53  RVRESDGELTVGERIDRERICRHTPQCLITFDVVNFSKDRYKLIHVAVEIRDINDNSPEF 112

Query: 151 SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS---- 206
             K   V + E+ +V     +    A DADVG+N    Y I   +    F+ID L     
Sbjct: 113 PNKESIVEISENAAVGSR--VPLDPAADADVGSNYIQSYQI---SVNSHFTIDVLLRADG 167

Query: 207 ---GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263
               ++ L+K LD E   SY + + A DGG P RS +T++ I + D NDN+P F  + F 
Sbjct: 168 VKYAELVLMKELDRETQSSYTVDLVATDGGHPFRSGSTKITILVTDFNDNSPVFDQNSFS 227

Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323
            ++ E+ P+G  I+ + A DAD+G+N E+ Y    K  +  +     +D +SG +     
Sbjct: 228 VTLPEDAPVGTVILNLNAVDADDGLNGEVVYGF-GKQVSHEIRQLFQVDHKSGRLTLRSP 286

Query: 324 LDRETQAKYQLLVTATD-GGDPPRS-------ATATXXXXXXXXXXXXXXFMPGQYEVEL 375
           +D E +  Y+L V ATD G +P  S        T                   G   +  
Sbjct: 287 VDFEEKTTYELDVQATDLGANPSPSLCKIIIHITDVNDNAPEISITPMTSMTTGIAYISE 346

Query: 376 AEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSI-TSQNGRGLITVAQPLDFKQE 434
           A D+     +++    D+  ++++H  + G      F +  +     +I  A  LD ++ 
Sbjct: 347 AADKDSLVALISTQDRDSGVNSQVHCSLYG---HDHFKLRQAYEDSYMIVTAASLDRERI 403

Query: 435 RRYVLTVSATDSGGRSDTAMVQ--INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492
             Y LTV A D G      ++Q  I ++D N+ AP F       SV E+ P G  +  V 
Sbjct: 404 SEYNLTVMAEDFGSPPMRKIIQYTIRLSDENDNAPHFARGVTEVSVVENNPPGAYITTVE 463

Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETMSGYLLTV 551
           A+D+D+  N +ITY L   + +  +      FV +N  +G++   +  + E M    + V
Sbjct: 464 ASDADLANNGKITYRL---VDSVIMGSPVNTFVSLNSVSGSLYALRSFNYEVMKQLDVHV 520

Query: 552 TARDGGVPSLSDTTDVEISVVDVNDNEP-VFKQQLYTAN----IMEDALVGTSVSQVGAT 606
            A DGG P L  T  + + ++D NDN+P + +  LY  +    + +D+  G  ++Q+ AT
Sbjct: 521 QASDGGSPQLQTTAVIRLKILDQNDNQPLIVEPPLYKGSAEVFLPKDSPGGYVLTQIKAT 580

Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
           DAD G+N ++ Y++   +     F I+  +G +  ++ L  +   T  +     D G+P 
Sbjct: 581 DADEGINAQLSYKI--IEGGHLGFSINKDTGKVHVSRQLTYDLSDTVKVTVAVSDNGSPS 638

Query: 667 QSSTVIVHIKIED--INDSPPVFESDCLTFY 695
            +ST I+H+   +  +   P + ++D   F+
Sbjct: 639 LTSTAIIHVSFTEGTLPSVPSLAQNDSEVFF 669



 Score =  213 bits (520), Expect = 6e-53
 Identities = 169/579 (29%), Positives = 268/579 (46%), Gaps = 42/579 (7%)

Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293
           S  R     + + IRD+NDN+P F        +SEN  +G  +    A DAD G N   +
Sbjct: 89  SKDRYKLIHVAVEIRDINDNSPEFPNKESIVEISENAAVGSRVPLDPAADADVGSNYIQS 148

Query: 294 YTMTDKDYTGNVDLPITIDP-RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352
           Y ++   +   +D+ +  D  +   +    +LDRETQ+ Y + + ATDGG P RS +   
Sbjct: 149 YQISVNSHF-TIDVLLRADGVKYAELVLMKELDRETQSSYTVDLVATDGGHPFRSGSTKI 207

Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG------ 406
                        F    + V L ED P GT ++ L A DAD+   L+ E+  G      
Sbjct: 208 TILVTDFNDNSPVFDQNSFSVTLPEDAPVGTVILNLNAVDADDG--LNGEVVYGFGKQVS 265

Query: 407 -NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQI--NITDAN 463
              R  F +  ++GR  +T+  P+DF+++  Y L V ATD G     ++ +I  +ITD N
Sbjct: 266 HEIRQLFQVDHKSGR--LTLRSPVDFEEKTTYELDVQATDLGANPSPSLCKIIIHITDVN 323

Query: 464 NYAPVFENAPYT------ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517
           + AP     P T      A + E A   + V ++S  D D G+N+Q+  SL      +  
Sbjct: 324 DNAPEISITPMTSMTTGIAYISEAADKDSLVALISTQDRDSGVNSQVHCSLYGHDHFKLR 383

Query: 518 AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577
             ++  ++I        T   LDRE +S Y LTV A D G P +       I + D NDN
Sbjct: 384 QAYEDSYMI-------VTAASLDRERISEYNLTVMAEDFGSPPMRKIIQYTIRLSDENDN 436

Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK---DREEGSFV-ID 633
            P F + +   +++E+   G  ++ V A+DAD+  NG+I Y L           +FV ++
Sbjct: 437 APHFARGVTEVSVVENNPPGAYITTVEASDADLANNGKITYRLVDSVIMGSPVNTFVSLN 496

Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS------PPVF 687
             SG +   ++ + E +   D+   A DGG+P   +T ++ +KI D ND+      PP++
Sbjct: 497 SVSGSLYALRSFNYEVMKQLDVHVQASDGGSPQLQTTAVIRLKILDQNDNQPLIVEPPLY 556

Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747
           +     F + ++SP G  + +I+A D DEG NA + Y I  G     FS+    G  K  
Sbjct: 557 KGSAEVF-LPKDSPGGYVLTQIKATDADEGINAQLSYKIIEGGHL-GFSINKDTG--KVH 612

Query: 748 LVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTD 786
           +   +  D     K    V    SP L +   + +  T+
Sbjct: 613 VSRQLTYDLSDTVKVTVAVSDNGSPSLTSTAIIHVSFTE 651



 Score =  198 bits (483), Expect = 2e-48
 Identities = 160/589 (27%), Positives = 267/589 (45%), Gaps = 55/589 (9%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           IH  + + D ND+SP F  ++    + E A+ G+ V    A D D+G N    Y I + +
Sbjct: 96  IHVAVEIRDINDNSPEFPNKESIVEISENAAVGSRVPLDPAADADVGSNYIQSYQISVNS 155

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASP 125
             T++                 + R DG +   L+    LDRE  + YTV + ATD   P
Sbjct: 156 HFTIDV----------------LLRADGVKYAELVLMKELDRETQSSYTVDLVATDGGHP 199

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
                S +  I + + D NDN P F + +++V++ ED  V    VI  + A DAD G N 
Sbjct: 200 FR---SGSTKITILVTDFNDNSPVFDQNSFSVTLPEDAPV--GTVILNLNAVDADDGLNG 254

Query: 186 AIRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
            + Y     +    +  F +D  SG ++L   +D+E+  +Y L ++A D G+    +  +
Sbjct: 255 EVVYGFGKQVSHEIRQLFQVDHKSGRLTLRSPVDFEEKTTYELDVQATDLGANPSPSLCK 314

Query: 243 LLINIRDVNDNAPRF----YTSLFQ--ESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
           ++I+I DVNDNAP       TS+      +SE       +  +   D D GVN+++  ++
Sbjct: 315 IIIHITDVNDNAPEISITPMTSMTTGIAYISEAADKDSLVALISTQDRDSGVNSQVHCSL 374

Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
              D+     L    +  S  + T+  LDRE  ++Y L V A D G PP           
Sbjct: 375 YGHDH---FKLRQAYED-SYMIVTAASLDRERISEYNLTVMAEDFGSPPMRKIIQYTIRL 430

Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRG---R 411
                    F  G  EV + E+ PPG  + T+ A+DAD   + ++ Y +      G    
Sbjct: 431 SDENDNAPHFARGVTEVSVVENNPPGAYITTVEASDADLANNGKITYRLVDSVIMGSPVN 490

Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVF 469
             ++  +  G +   +  +++  ++  + V A+D G      TA++++ I D N+  P+ 
Sbjct: 491 TFVSLNSVSGSLYALRSFNYEVMKQLDVHVQASDGGSPQLQTTAVIRLKILDQNDNQPLI 550

Query: 470 ENAPY---TASVF--EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524
              P    +A VF  +D+P G  +  + ATD+D GINAQ++Y +        +      F
Sbjct: 551 VEPPLYKGSAEVFLPKDSPGGYVLTQIKATDADEGINAQLSYKI--------IEGGHLGF 602

Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
            IN  TG +  ++ L  +      +TV   D G PSL+ T  + +S  +
Sbjct: 603 SINKDTGKVHVSRQLTYDLSDTVKVTVAVSDNGSPSLTSTAIIHVSFTE 651



 Score =  177 bits (430), Expect = 5e-42
 Identities = 160/529 (30%), Positives = 240/529 (45%), Gaps = 51/529 (9%)

Query: 377 EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS---ITSQNGRGLITVAQPLDFKQ 433
           E+  PGT + TL     D    L    T      +F+   I  +   G +TV + +D ++
Sbjct: 15  EEGAPGTVIGTLAK---DMSLSLSSSKTNFRMMKQFNDSFIRVRESDGELTVGERIDRER 71

Query: 434 ERRY----VLTVSATD-SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
             R+    ++T    + S  R     V + I D N+ +P F N      + E+A +G+ V
Sbjct: 72  ICRHTPQCLITFDVVNFSKDRYKLIHVAVEIRDINDNSPEFPNKESIVEISENAAVGSRV 131

Query: 489 LVVSATDSDVGINAQITYSLS--SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
            +  A D+DVG N   +Y +S  S  + + +   D       +   +   K LDRET S 
Sbjct: 132 PLDPAADADVGSNYIQSYQISVNSHFTIDVLLRAD-----GVKYAELVLMKELDRETQSS 186

Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
           Y + + A DGG P  S +T + I V D NDN PVF Q  ++  + EDA VGT +  + A 
Sbjct: 187 YTVDLVATDGGHPFRSGSTKITILVTDFNDNSPVFDQNSFSVTLPEDAPVGTVILNLNAV 246

Query: 607 DADVGLNGRIHYELDPKDREE--GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
           DAD GLNG + Y    +   E    F +D  SG +     +D E   T++L   A D G 
Sbjct: 247 DADDGLNGEVVYGFGKQVSHEIRQLFQVDHKSGRLTLRSPVDFEEKTTYELDVQATDLGA 306

Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLT------FYISENSPIGTTIGEIRAHDPDEGP 718
            P  S   + I I D+ND+ P      +T       YISE +   + +  I   D D G 
Sbjct: 307 NPSPSLCKIIIHITDVNDNAPEISITPMTSMTTGIAYISEAADKDSLVALISTQDRDSGV 366

Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLW 775
           N+ VH S+ G D    F L  +   D   +VT   LD E    +Y L + A    SPP+ 
Sbjct: 367 NSQVHCSLYGHD---HFKLR-QAYEDSYMIVTAASLDRER-ISEYNLTVMAEDFGSPPMR 421

Query: 776 NDVRVEILVTDVNDNAP----VMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTD--KLQ 828
             ++  I ++D NDNAP     + +  ++ NN     P G +   V A DAD+ +  K+ 
Sbjct: 422 KIIQYTIRLSDENDNAPHFARGVTEVSVVENN-----PPGAYITTVEASDADLANNGKIT 476

Query: 829 YR----ILSGNNAN-LILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
           YR    ++ G+  N  + LN  +GS+      N  V K   + V  +DG
Sbjct: 477 YRLVDSVIMGSPVNTFVSLNSVSGSLYALRSFNYEVMKQLDVHVQASDG 525



 Score =  176 bits (429), Expect = 6e-42
 Identities = 145/500 (29%), Positives = 227/500 (45%), Gaps = 43/500 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V D ND+SPVF+   +  ++ E A  GT +L L A D D G N EV Y          
Sbjct: 209 ILVTDFNDNSPVFDQNSFSVTLPEDAPVGTVILNLNAVDADDGLNGEVVYGF-------- 260

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                          ++ +F++D +SG L  R+ +D E+   Y + V+ATD  +  S   
Sbjct: 261 --------GKQVSHEIRQLFQVDHKSGRLTLRSPVDFEEKTTYELDVQATDLGANPS--- 309

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTD----NPVIAKIKATDADVGANSA 186
            S   I ++I D NDN P+ S    T        +++    + ++A I   D D G NS 
Sbjct: 310 PSLCKIIIHITDVNDNAPEISITPMTSMTTGIAYISEAADKDSLVALISTQDRDSGVNSQ 369

Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
           +  ++ G +    F +     D  ++ T   LD E++  Y L + A+D GSP      Q 
Sbjct: 370 VHCSLYGHD---HFKLRQAYEDSYMIVTAASLDRERISEYNLTVMAEDFGSPPMRKIIQY 426

Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
            I + D NDNAP F   + + SV EN P G  I  V+A DAD   N ++TY + D    G
Sbjct: 427 TIRLSDENDNAPHFARGVTEVSVVENNPPGAYITTVEASDADLANNGKITYRLVDSVIMG 486

Query: 304 N-VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
           + V+  ++++  SG +Y     + E   +  + V A+DGG P    TA            
Sbjct: 487 SPVNTFVSLNSVSGSLYALRSFNYEVMKQLDVHVQASDGGSPQLQTTAVIRLKILDQNDN 546

Query: 363 XXXFM-----PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSIT 415
               +      G  EV L +D P G  +  + ATDADE  + +L Y+I  G   G FSI 
Sbjct: 547 QPLIVEPPLYKGSAEVFLPKDSPGGYVLTQIKATDADEGINAQLSYKIIEGGHLG-FSIN 605

Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAP 473
              G+  + V++ L +       +TV+ +D+G  S   TA++ ++ T+      V   A 
Sbjct: 606 KDTGK--VHVSRQLTYDLSDTVKVTVAVSDNGSPSLTSTAIIHVSFTE-GTLPSVPSLAQ 662

Query: 474 YTASVFEDAPIGTTVLVVSA 493
             + VF +      +++V A
Sbjct: 663 NDSEVFFEWDTSIAIIIVLA 682



 Score =  172 bits (418), Expect = 1e-40
 Identities = 145/526 (27%), Positives = 252/526 (47%), Gaps = 38/526 (7%)

Query: 373 VELAEDEPPGTPVVTLTATDADEDNRL--HYEITGGNTRGRFSITSQNG--RGLITVAQP 428
           VE++E+   G+ V    A DAD  +     Y+I+  +      +   +G     + + + 
Sbjct: 119 VEISENAAVGSRVPLDPAADADVGSNYIQSYQISVNSHFTIDVLLRADGVKYAELVLMKE 178

Query: 429 LDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
           LD + +  Y + + ATD G   RS +  + I +TD N+ +PVF+   ++ ++ EDAP+GT
Sbjct: 179 LDRETQSSYTVDLVATDGGHPFRSGSTKITILVTDFNDNSPVFDQNSFSVTLPEDAPVGT 238

Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
            +L ++A D+D G+N ++ Y    ++S+E      Q F ++ ++G +T    +D E  + 
Sbjct: 239 VILNLNAVDADDGLNGEVVYGFGKQVSHEI----RQLFQVDHKSGRLTLRSPVDFEEKTT 294

Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT------ANIMEDALVGTSV 600
           Y L V A D G         + I + DVNDN P       T      A I E A   + V
Sbjct: 295 YELDVQATDLGANPSPSLCKIIIHITDVNDNAPEISITPMTSMTTGIAYISEAADKDSLV 354

Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
           + +   D D G+N ++H  L   D  +     +  S +I T  +LDRE ++ ++L  +A 
Sbjct: 355 ALISTQDRDSGVNSQVHCSLYGHDHFKLRQAYED-SYMIVTAASLDRERISEYNLTVMAE 413

Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
           D G+PP    +   I++ D ND+ P F        + EN+P G  I  + A D D   N 
Sbjct: 414 DFGSPPMRKIIQYTIRLSDENDNAPHFARGVTEVSVVENNPPGAYITTVEASDADLANNG 473

Query: 721 VVHY----SIKGGDDSNSF-SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SP 772
            + Y    S+  G   N+F SL +  GS    L  +   +YE   K+ ++ ++A+   SP
Sbjct: 474 KITYRLVDSVIMGSPVNTFVSLNSVSGS----LYALRSFNYEV-MKQLDVHVQASDGGSP 528

Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFG----RVPAYDAD--VTD 825
            L     + + + D NDN P++ +  +   + +   P   P G    ++ A DAD  +  
Sbjct: 529 QLQTTAVIRLKILDQNDNQPLIVEPPLYKGSAEVFLPKDSPGGYVLTQIKATDADEGINA 588

Query: 826 KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
           +L Y+I+ G +     +N+ TG + +S QL  ++     + V+V+D
Sbjct: 589 QLSYKIIEGGHLG-FSINKDTGKVHVSRQLTYDLSDTVKVTVAVSD 633


>UniRef50_Q95YK1 Cluster: Protocadherin; n=1; Ciona savignyi|Rep:
           Protocadherin - Ciona savignyi (Pacific transparent sea
           squirt)
          Length = 1177

 Score =  215 bits (524), Expect = 2e-53
 Identities = 188/636 (29%), Positives = 281/636 (44%), Gaps = 50/636 (7%)

Query: 88  DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
           D   +   SG +  R  +DRE             QA  +  R+ S   + + I D NDN 
Sbjct: 84  DAVDLGTSSGLITLRRRVDRETECGQAKECIIKVQAVMLPQRVFSLLNLEIVITDTNDNA 143

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNT--QMQFSIDSL 205
           P F  K   V+V E ++V D   +   +A D D G NSAI Y I         Q+  ++ 
Sbjct: 144 PTFPHKPIIVNVSESVTVNDIINLDSFQARDLDSGNNSAITYTIAPSQPFGVNQYIDEAG 203

Query: 206 SGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263
              + L+ T  LDYE  + + L + A D G+P  SN   L I + D ND++P F  S F 
Sbjct: 204 RPHLQLIVTSELDYETKQVHHLTLYATDNGTPPLSNNVALRILVTDANDHSPVFAQSEFV 263

Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323
           + + EN P G+ I RV A D D G N  + Y + D+    +  L +T+D  +G V     
Sbjct: 264 KELKENQPPGF-ITRVHAVDRDSGNNGRVQYFLGDESEAVSHQL-VTVDKDTGDVTLVQN 321

Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE-------LA 376
           LDRET    ++L+ A D     + ++                 +   + V+       ++
Sbjct: 322 LDRETHDGMRILIEARDSAPTNQRSSRMWLVLRIDDDNDNAPTINMNFIVDADGQTAYIS 381

Query: 377 EDEPPGTPVVTLTATDADEDNRLHYEIT----------GGNTRGRFSITSQNGRGLITVA 426
           E  P GT V  ++A+DAD       +I+            NT G F + +    GLI   
Sbjct: 382 EASPIGTYVAYVSASDADHGKNSEVDISIRTLVFGEPEYANT-GHFVLAAD---GLIGTG 437

Query: 427 QPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
             LD + +  Y + V A D+G   RS    + + I D N+ APVF+   Y  ++ E   +
Sbjct: 438 LELDREIQNSYKVVVEARDAGDVPRSSFNNITVIILDENDNAPVFQKPVYPVTLSEADGV 497

Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEI---SNEAVAH----HDQQFVINPQTGAITTNK 537
           GTTV  VSATD D       T +   EI    N  V +     D  F IN +TG IT  +
Sbjct: 498 GTTVTTVSATDKDALFPPVWTKNKKKEIVPSMNGKVTYLIDSDDNTFSINAETGEITLVR 557

Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF-KQQLYTANIMEDALV 596
            LDRE  S + +T+ ARDGG P    T  +++ V DVNDN P+F    +  +      L 
Sbjct: 558 PLDREGQSDWEVTIIARDGGSPYKESTCILKVVVSDVNDNRPLFINPAIDNSTAYATILR 617

Query: 597 GTSVSQVGATDADVGLNGRIHYEL----DPKDREE-------GSFVIDPASGVIRTNKAL 645
              ++++ A D D  +  ++   L      K  +E         FV+D A+G +R N + 
Sbjct: 618 DDVITRIQAVDYDSPMFSKVEISLLSVDGLKSTQETDGVEPYSFFVLDRATGDLRLNMST 677

Query: 646 D--RESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679
               + V +H +   A D G PP  S   + I + D
Sbjct: 678 ADLNDIVGSHVIVVKATDNGQPPLESRTSITIIVSD 713



 Score =  194 bits (472), Expect = 4e-47
 Identities = 176/620 (28%), Positives = 282/620 (45%), Gaps = 50/620 (8%)

Query: 206 SGDVSLVKTLDYEQV--RSYRLVIRAQDGGSPSRS-NTTQLLINIRDVNDNAPRFYTSLF 262
           SG ++L + +D E    ++   +I+ Q    P R  +   L I I D NDNAP F     
Sbjct: 92  SGLITLRRRVDRETECGQAKECIIKVQAVMLPQRVFSLLNLEIVITDTNDNAPTFPHKPI 151

Query: 263 QESVSENVPIG--YSIVRVQAYDADEGVNAELTYTMTDKDYTG-NVDLPITIDPRSGWVY 319
             +VSE+V +    ++   QA D D G N+ +TYT+      G N  +     P    + 
Sbjct: 152 IVNVSESVTVNDIINLDSFQARDLDSGNNSAITYTIAPSQPFGVNQYIDEAGRPHLQLIV 211

Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE 379
           TS +LD ET+  + L + ATD G PP S                  F   ++  EL E++
Sbjct: 212 TS-ELDYETKQVHHLTLYATDNGTPPLSNNVALRILVTDANDHSPVFAQSEFVKELKENQ 270

Query: 380 PPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS---ITSQNGRGLITVAQPLDFKQERR 436
           PPG  +  + A D D  N    +   G+     S   +T     G +T+ Q LD +    
Sbjct: 271 PPGF-ITRVHAVDRDSGNNGRVQYFLGDESEAVSHQLVTVDKDTGDVTLVQNLDRETHDG 329

Query: 437 YVLTVSATDSGG---RSDTAMVQINITDANNYAP------VFENAPYTASVFEDAPIGTT 487
             + + A DS     RS    + + I D N+ AP      + +    TA + E +PIGT 
Sbjct: 330 MRILIEARDSAPTNQRSSRMWLVLRIDDDNDNAPTINMNFIVDADGQTAYISEASPIGTY 389

Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
           V  VSA+D+D G N+++  S+ + +  E    +   FV+    G I T   LDRE  + Y
Sbjct: 390 VAYVSASDADHGKNSEVDISIRTLVFGEPEYANTGHFVLAAD-GLIGTGLELDREIQNSY 448

Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
            + V ARD G    S   ++ + ++D NDN PVF++ +Y   + E   VGT+V+ V ATD
Sbjct: 449 KVVVEARDAGDVPRSSFNNITVIILDENDNAPVFQKPVYPVTLSEADGVGTTVTTVSATD 508

Query: 608 ADV----------------GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA 651
            D                  +NG++ Y +D  D    +F I+  +G I   + LDRE  +
Sbjct: 509 KDALFPPVWTKNKKKEIVPSMNGKVTYLIDSDD---NTFSINAETGEITLVRPLDREGQS 565

Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI-GTTIGEIR 710
             ++  +A DGG+P + ST I+ + + D+ND+ P+F +  +    +  + +    I  I+
Sbjct: 566 DWEVTIIARDGGSPYKESTCILKVVVSDVNDNRPLFINPAIDNSTAYATILRDDVITRIQ 625

Query: 711 AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770
           A D D    + V  S+   D      L++ Q +D  E  +   LD    R   +L +  +
Sbjct: 626 AVDYDSPMFSKVEISLLSVD-----GLKSTQETDGVEPYSFFVLD----RATGDLRLNMS 676

Query: 771 SPPLWNDVRVEILVTDVNDN 790
           +  L + V   ++V    DN
Sbjct: 677 TADLNDIVGSHVIVVKATDN 696



 Score =  157 bits (381), Expect = 4e-36
 Identities = 155/609 (25%), Positives = 265/609 (43%), Gaps = 67/609 (11%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVL--TLKATDQDIGKNAEVEYTIEL 64
           ++ +I + D ND++P F  +    +V E  +    +   + +A D D G N+ + YTI  
Sbjct: 130 LNLEIVITDTNDNAPTFPHKPIIVNVSESVTVNDIINLDSFQARDLDSGNNSAITYTIAP 189

Query: 65  VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS 124
                +N               Q +         L+  + LD E    + + + ATD  +
Sbjct: 190 SQPFGVN---------------QYIDEAGRPHLQLIVTSELDYETKQVHHLTLYATDNGT 234

Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184
           P    LS+   + + + D ND+ P F++  +   + E+        I ++ A D D G N
Sbjct: 235 PP---LSNNVALRILVTDANDHSPVFAQSEFVKELKEN---QPPGFITRVHAVDRDSGNN 288

Query: 185 SAIRYAIIGGNTQ----MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG-SPSRSN 239
             ++Y  +G  ++       ++D  +GDV+LV+ LD E     R++I A+D   +  RS+
Sbjct: 289 GRVQY-FLGDESEAVSHQLVTVDKDTGDVTLVQNLDRETHDGMRILIEARDSAPTNQRSS 347

Query: 240 TTQLLINIRDVNDNAPRFYTSLFQES------VSENVPIGYSIVRVQAYDADEGVNAEL- 292
              L++ I D NDNAP    +   ++      +SE  PIG  +  V A DAD G N+E+ 
Sbjct: 348 RMWLVLRIDDDNDNAPTINMNFIVDADGQTAYISEASPIGTYVAYVSASDADHGKNSEVD 407

Query: 293 ----TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348
               T    + +Y       +  D   G + T  +LDRE Q  Y+++V A D GD PRS+
Sbjct: 408 ISIRTLVFGEPEYANTGHFVLAAD---GLIGTGLELDREIQNSYKVVVEARDAGDVPRSS 464

Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD-------EDNRLHY 401
                            F    Y V L+E +  GT V T++ATD D         N+   
Sbjct: 465 FNNITVIILDENDNAPVFQKPVYPVTLSEADGVGTTVTTVSATDKDALFPPVWTKNKKKE 524

Query: 402 EITGGNTRGRFSITSQNG-------RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDT 452
            +   N +  + I S +         G IT+ +PLD + +  + +T+ A D G   +  T
Sbjct: 525 IVPSMNGKVTYLIDSDDNTFSINAETGEITLVRPLDREGQSDWEVTIIARDGGSPYKEST 584

Query: 453 AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV-VSATDSDVGINAQITYSLSSE 511
            ++++ ++D N+  P+F N     S      +   V+  + A D D  + +++  SL S 
Sbjct: 585 CILKVVVSDVNDNRPLFINPAIDNSTAYATILRDDVITRIQAVDYDSPMFSKVEISLLSV 644

Query: 512 ISNEAVAHHD-----QQFVINPQTGAITTN-KLLD-RETMSGYLLTVTARDGGVPSLSDT 564
              ++    D       FV++  TG +  N    D  + +  +++ V A D G P L   
Sbjct: 645 DGLKSTQETDGVEPYSFFVLDRATGDLRLNMSTADLNDIVGSHVIVVKATDNGQPPLESR 704

Query: 565 TDVEISVVD 573
           T + I V D
Sbjct: 705 TSITIIVSD 713



 Score =  137 bits (331), Expect = 5e-30
 Identities = 122/400 (30%), Positives = 197/400 (49%), Gaps = 34/400 (8%)

Query: 421 GLITVAQPLDFKQE----RRYVLTVSATDSGGRSDTAM-VQINITDANNYAPVFENAPYT 475
           GLIT+ + +D + E    +  ++ V A     R  + + ++I ITD N+ AP F + P  
Sbjct: 93  GLITLRRRVDRETECGQAKECIIKVQAVMLPQRVFSLLNLEIVITDTNDNAPTFPHKPII 152

Query: 476 ASVFEDAPIGTTVLVVS--ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
            +V E   +   + + S  A D D G N+ ITY+++         + D+     P    I
Sbjct: 153 VNVSESVTVNDIINLDSFQARDLDSGNNSAITYTIAPSQPFGVNQYIDEAG--RPHLQLI 210

Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593
            T++L D ET   + LT+ A D G P LS+   + I V D ND+ PVF Q  +   + E+
Sbjct: 211 VTSEL-DYETKQVHHLTLYATDNGTPPLSNNVALRILVTDANDHSPVFAQSEFVKELKEN 269

Query: 594 ALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFV-IDPASGVIRTNKALDRESVA 651
              G  +++V A D D G NGR+ Y L D  +      V +D  +G +   + LDRE   
Sbjct: 270 QPPGF-ITRVHAVDRDSGNNGRVQYFLGDESEAVSHQLVTVDKDTGDVTLVQNLDRE--- 325

Query: 652 THDLKAVAIDGG----TPPQSSTVIVHIKIEDINDSPP------VFESDCLTFYISENSP 701
           THD   + I+      T  +SS + + ++I+D ND+ P      + ++D  T YISE SP
Sbjct: 326 THDGMRILIEARDSAPTNQRSSRMWLVLRIDDDNDNAPTINMNFIVDADGQTAYISEASP 385

Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKG---GDDSNSFSLETRQGSDKAELVTMVDLDYES 758
           IGT +  + A D D G N+ V  SI+    G+   + +      +D   + T ++LD E 
Sbjct: 386 IGTYVAYVSASDADHGKNSEVDISIRTLVFGEPEYANTGHFVLAADGL-IGTGLELDREI 444

Query: 759 PRKKYELVIRAASP---PLWNDVRVEILVTDVNDNAPVMK 795
            +  Y++V+ A      P  +   + +++ D NDNAPV +
Sbjct: 445 -QNSYKVVVEARDAGDVPRSSFNNITVIILDENDNAPVFQ 483



 Score = 81.0 bits (191), Expect = 4e-13
 Identities = 79/309 (25%), Positives = 136/309 (44%), Gaps = 23/309 (7%)

Query: 612 LNGRIHYE--LDPKDREEGSFVID--PASGVIRTNKALDRESVATHDLKAVA-IDGGTPP 666
           LN + H      P  R      +D   +SG+I   + +DRE+      + +  +     P
Sbjct: 64  LNQKFHSSSMFSPSARRHRPDAVDLGTSSGLITLRRRVDRETECGQAKECIIKVQAVMLP 123

Query: 667 QS--STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG--EIRAHDPDEGPNAVV 722
           Q   S + + I I D ND+ P F    +   +SE+  +   I     +A D D G N+ +
Sbjct: 124 QRVFSLLNLEIVITDTNDNAPTFPHKPIIVNVSESVTVNDIINLDSFQARDLDSGNNSAI 183

Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVR 779
            Y+I               G    +L+   +LDYE+ ++ + L + A    +PPL N+V 
Sbjct: 184 TYTIAPSQPFGVNQYIDEAGRPHLQLIVTSELDYET-KQVHHLTLYATDNGTPPLSNNVA 242

Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNA 837
           + ILVTD ND++PV    + +    K+  P G   RV A D D     ++QY +   + A
Sbjct: 243 LRILVTDANDHSPVFAQSEFV-KELKENQPPGFITRVHAVDRDSGNNGRVQYFLGDESEA 301

Query: 838 ---NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG--VNEIKAMMQLSVRLITEEML 892
               L+ +++ TG +TL   L+        + +   D    N+  + M L +R+  +   
Sbjct: 302 VSHQLVTVDKDTGDVTLVQNLDRETHDGMRILIEARDSAPTNQRSSRMWLVLRIDDDND- 360

Query: 893 LNSITVRLN 901
            N+ T+ +N
Sbjct: 361 -NAPTINMN 368


>UniRef50_Q9Y5H3 Cluster: Protocadherin gamma A10 precursor; n=119;
           Amniota|Rep: Protocadherin gamma A10 precursor - Homo
           sapiens (Human)
          Length = 936

 Score =  215 bits (524), Expect = 2e-53
 Identities = 179/608 (29%), Positives = 272/608 (44%), Gaps = 32/608 (5%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           +F ++ RSG+L+T   +DRE++   +     +     V DR+     I + + D NDN P
Sbjct: 78  LFSLNPRSGSLITAGRIDREELCAQSARCVVSFNIL-VEDRVKLFG-IEIEVTDINDNAP 135

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
           +F  +   V ++E+++      + +  A D DVG NS   Y +   N      + S +  
Sbjct: 136 KFQAENLDVKINENVAAGMRFPLPE--AIDPDVGVNSLQSYQL-SPNKHFSLRVQSRANG 192

Query: 209 VS-----LVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263
           V      L  +LD E+   + LV+ A DGG P RS T  + + + D NDNAP F    ++
Sbjct: 193 VKYPELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYR 252

Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323
            SV EN+P+G  ++ V A D DEG N E+TY+   +       L   ++  +G +  S  
Sbjct: 253 VSVPENLPVGTQLLTVTATDRDEGANGEVTYSF--RKLPDTQLLKFQLNKYTGEIKISEN 310

Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383
           LD E    Y++ + A DGG     ATA                        + ED P GT
Sbjct: 311 LDYEETGFYEIEIQAEDGG--AYLATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGT 368

Query: 384 PVVTLTATDADEDNRLHYEITGGNTRG-RFSI-TSQNGRGLITVAQPLDFKQERRYVLTV 441
            V  L   D D +   + ++T        F +  S +    + + + LD +Q   Y +TV
Sbjct: 369 VVALLNVHDLDSEQ--NGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITV 426

Query: 442 SATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499
           +ATD G    S  A   + + D N+  P F    Y   + E+   G ++  V+A D D  
Sbjct: 427 TATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSK 486

Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
            NAQI YSL+ +              IN  TG +   +  D E      + VTA D G P
Sbjct: 487 ENAQIIYSLAEDTIQGVPL--SSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDP 544

Query: 560 SLSDTTDVEISVVDVNDNEP-VFKQQLYTAN------IMEDALVGTSVSQVGATDADVGL 612
            LS    + + V+D NDN P +    L T            A  G  V++V A D D G 
Sbjct: 545 PLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQ 604

Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKA-LDRESVATHDLKAVAIDGGTPPQSSTV 671
           N  + Y L  K  E G F +   +G +RT +A LDR+++    + AV  D G PP S+TV
Sbjct: 605 NAWLSYRL-LKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQ-DHGQPPLSATV 662

Query: 672 IVHIKIED 679
            + + + D
Sbjct: 663 TLTVAVAD 670



 Score =  214 bits (522), Expect = 3e-53
 Identities = 171/611 (27%), Positives = 280/611 (45%), Gaps = 32/611 (5%)

Query: 194 GNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251
           G TQ+ FS++  SG +     +D E++  +S R V+ + +     R     + I + D+N
Sbjct: 74  GRTQL-FSLNPRSGSLITAGRIDREELCAQSARCVV-SFNILVEDRVKLFGIEIEVTDIN 131

Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT-DKDYTGNVDLPIT 310
           DNAP+F        ++ENV  G      +A D D GVN+  +Y ++ +K ++  V     
Sbjct: 132 DNAPKFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRAN 191

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
              +   +     LDRE +A + L++TA+DGGDP RS T                F   +
Sbjct: 192 -GVKYPELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPE 250

Query: 371 YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
           Y V + E+ P GT ++T+TATD DE  +  + Y                   G I +++ 
Sbjct: 251 YRVSVPENLPVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLLKFQLNKYTGEIKISEN 310

Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
           LD+++   Y + + A D G    TA V I + D N+ +P        + V ED+P+GT V
Sbjct: 311 LDYEETGFYEIEIQAEDGGAYLATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGTVV 370

Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
            +++  D D   N Q+T S+ + +  +     D  +        +  ++ LDRE +S Y 
Sbjct: 371 ALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYY-------RLVIHRALDREQVSSYN 423

Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
           +TVTA DGG P LS      + V D+NDN P F Q  Y   I E+   G S+  V A D 
Sbjct: 424 ITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDP 483

Query: 609 DVGLNGRIHYELDPKDREEG----SFV-IDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
           D   N +I Y L  +D  +G    S++ I+  +GV+   ++ D E      ++  A D G
Sbjct: 484 DSKENAQIIYSL-AEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSG 542

Query: 664 TPPQSSTVIVHIKIEDINDSP-----PVFESDCLT--FYISENSPIGTTIGEIRAHDPDE 716
            PP SS V + + + D ND+      P   +D  T       ++  G  + ++ A D D 
Sbjct: 543 DPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDS 602

Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR-AASPPLW 775
           G NA + Y +    +   F++    G  +        LD ++ ++   + ++    PPL 
Sbjct: 603 GQNAWLSYRLLKASEPGLFAVGEHTGEVRTARAL---LDRDALKQSLVVAVQDHGQPPLS 659

Query: 776 NDVRVEILVTD 786
             V + + V D
Sbjct: 660 ATVTLTVAVAD 670



 Score =  192 bits (469), Expect = 9e-47
 Identities = 170/597 (28%), Positives = 269/597 (45%), Gaps = 32/597 (5%)

Query: 310 TIDPRSGWVYTSGQLDRETQ-AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
           +++PRSG + T+G++DRE   A+    V + +     R                   F  
Sbjct: 80  SLNPRSGSLITAGRIDREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAPKFQA 139

Query: 369 GQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQ-NGRGL--IT 424
              +V++ E+   G       A D D   N L       N      + S+ NG     + 
Sbjct: 140 ENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKYPELV 199

Query: 425 VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
           +   LD ++E  + L ++A+D G   RS T +V + + DAN+ APVF    Y  SV E+ 
Sbjct: 200 LEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVPENL 259

Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
           P+GT +L V+ATD D G N ++TYS       + +     +F +N  TG I  ++ LD E
Sbjct: 260 PVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLL-----KFQLNKYTGEIKISENLDYE 314

Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
               Y + + A DGG  +   T  V I+V DVNDN P        + + ED+ +GT V+ 
Sbjct: 315 ETGFYEIEIQAEDGG--AYLATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVAL 372

Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
           +   D D   NG++   +      +    ID    ++  ++ALDRE V+++++   A DG
Sbjct: 373 LNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLV-IHRALDREQVSSYNITVTATDG 431

Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
           G+PP S+     +++ DIND+PP F       YI EN+  G +I  + A DPD   NA +
Sbjct: 432 GSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENAQI 491

Query: 723 HYSIKGGDDSNSFSLET--RQGSDKAELVTMVDLDYESPRKKYELVIRAAS--PPLWNDV 778
            YS+   D      L +     SD   L  +   DYE   +    V  + S  PPL ++V
Sbjct: 492 IYSL-AEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPLSSNV 550

Query: 779 RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY----------DADVTDKLQ 828
            + + V D NDNAP +  +  +  +      + P    P Y          D+     L 
Sbjct: 551 SLSLFVLDQNDNAPEIL-YPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLS 609

Query: 829 YRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSV 884
           YR+L  +   L  + E TG +  +  L        ++ V+V D G   + A + L+V
Sbjct: 610 YRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTV 666



 Score =  191 bits (466), Expect = 2e-46
 Identities = 168/583 (28%), Positives = 268/583 (45%), Gaps = 55/583 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +I V D ND++P F+ +  +  + E  ++G      +A D D+G N+   Y         
Sbjct: 124 EIEVTDINDNAPKFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSY--------Q 175

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
           L+P             VQ   R +G +   L+   SLDRE+ A + +++ A+D   P+  
Sbjct: 176 LSPN------KHFSLRVQS--RANGVKYPELVLEHSLDREEEAIHHLVLTASDGGDPLR- 226

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             S T  + V + D NDN P F+   Y VSV E++ V     +  + ATD D GAN  + 
Sbjct: 227 --SGTVLVSVTVFDANDNAPVFTLPEYRVSVPENLPV--GTQLLTVTATDRDEGANGEVT 282

Query: 189 YAI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           Y+   +     ++F ++  +G++ + + LDYE+   Y + I+A+DGG  +   T ++LI 
Sbjct: 283 YSFRKLPDTQLLKFQLNKYTGEIKISENLDYEETGFYEIEIQAEDGG--AYLATAKVLIT 340

Query: 247 IRDVNDNAPRF-YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
           + DVNDN+P    TSLF   V+E+ P+G  +  +  +D D   N ++T ++    Y    
Sbjct: 341 VEDVNDNSPELTITSLF-SPVTEDSPLGTVVALLNVHDLDSEQNGQVTCSIL--AYL-PF 396

Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
            L  +ID     V     LDRE  + Y + VTATDGG PP S  A               
Sbjct: 397 KLEKSIDSYYRLVIHRA-LDREQVSSYNITVTATDGGSPPLSTEAHFMLQVADINDNPPT 455

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRG---RFSITSQNGR 420
           F    Y   + E+   G  + ++TA D D  E+ ++ Y +     +G      I+  +  
Sbjct: 456 FSQVSYFTYIPENNARGASIFSVTALDPDSKENAQIIYSLAEDTIQGVPLSSYISINSDT 515

Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAP--VFENAPYTA 476
           G++   +  D++Q     + V+A+DSG    S    + + + D N+ AP  ++   P   
Sbjct: 516 GVLYALRSFDYEQFHELQMQVTASDSGDPPLSSNVSLSLFVLDQNDNAPEILYPALPTDG 575

Query: 477 SV-FEDAP----IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
           S   E AP     G  V  V A D D G NA ++Y L         A     F +   TG
Sbjct: 576 STGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLK-------ASEPGLFAVGEHTG 628

Query: 532 AI-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
            + T   LLDR+ +    L V  +D G P LS T  + ++V D
Sbjct: 629 EVRTARALLDRDALK-QSLVVAVQDHGQPPLSATVTLTVAVAD 670



 Score =  156 bits (378), Expect = 9e-36
 Identities = 129/469 (27%), Positives = 208/469 (44%), Gaps = 38/469 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + V D ND++PVF + +Y  SV E    GT +LT+ ATD+D G N EV Y+   +    L
Sbjct: 234 VTVFDANDNAPVFTLPEYRVSVPENLPVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQL 293

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                              F+++  +G +    +LD E+   Y + ++A D  + ++   
Sbjct: 294 LK-----------------FQLNKYTGEIKISENLDYEETGFYEIEIQAEDGGAYLA--- 333

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             TA + + + D NDN P+ +  +    V ED  +    V+A +   D D   N  +  +
Sbjct: 334 --TAKVLITVEDVNDNSPELTITSLFSPVTEDSPL--GTVVALLNVHDLDSEQNGQVTCS 389

Query: 191 IIGGNT-QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
           I+     +++ SIDS    V + + LD EQV SY + + A DGGSP  S     ++ + D
Sbjct: 390 ILAYLPFKLEKSIDSYYRLV-IHRALDREQVSSYNITVTATDGGSPPLSTEAHFMLQVAD 448

Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NVDLP 308
           +NDN P F    +   + EN   G SI  V A D D   NA++ Y++ +    G  +   
Sbjct: 449 INDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENAQIIYSLAEDTIQGVPLSSY 508

Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM- 367
           I+I+  +G +Y     D E   + Q+ VTA+D GDPP S+  +               + 
Sbjct: 509 ISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPLSSNVSLSLFVLDQNDNAPEILY 568

Query: 368 -----PGQYEVELA-EDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNG 419
                 G   VELA     PG  V  + A D D      L Y +   +  G F++    G
Sbjct: 569 PALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTG 628

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468
              +  A+ L  +   +  L V+  D G    +A V + +  A++   V
Sbjct: 629 E--VRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPQV 675



 Score = 78.2 bits (184), Expect = 3e-12
 Identities = 58/247 (23%), Positives = 101/247 (40%), Gaps = 22/247 (8%)

Query: 8   HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
           H  + V D ND+ P F    Y   + E  + G ++ ++ A D D  +NA++ Y++     
Sbjct: 441 HFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENAQIIYSL---AE 497

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
           DT+               +     I+  +G L    S D E+     + V A+D   P  
Sbjct: 498 DTIQ-----------GVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDP-- 544

Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI-----SVTDNPVIAKIKATDADVG 182
             LSS  ++ + ++D NDN P+             +     S     ++ K+ A D D G
Sbjct: 545 -PLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSG 603

Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
            N+ + Y ++  +    F++   +G+V   + L         LV+  QD G P  S T  
Sbjct: 604 QNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVT 663

Query: 243 LLINIRD 249
           L + + D
Sbjct: 664 LTVAVAD 670


>UniRef50_UPI00004F6724 Cluster: protocadherin 1 gamma 1; n=3; Danio
           rerio|Rep: protocadherin 1 gamma 1 - Danio rerio
          Length = 932

 Score =  214 bits (522), Expect = 3e-53
 Identities = 164/561 (29%), Positives = 256/561 (45%), Gaps = 33/561 (5%)

Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195
           I + + D NDN P F + +  + + E         +   +A D DVG NS   Y +   +
Sbjct: 116 IALEVQDVNDNPPVFPKGSIKLEISEGAPTGSK--LQLTRARDLDVGINSVQTYIL---S 170

Query: 196 TQMQFSIDSLSG-----DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
               F +D+ S      D+ L  +LD E    + L++ A DGG+P  S T  + + + D+
Sbjct: 171 QNKHFVLDTKSSKDRYVDIVLKNSLDRETRGEHSLILSAVDGGNPPNSGTVVIEVVVIDM 230

Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
           NDNAP F   L+   +SEN  +G S++++ A D DEG N E+ Y +     + N      
Sbjct: 231 NDNAPLFSQPLYNARLSENSALGTSVIKITATDEDEGANGEIKYYI--NHLSDNTKQLFK 288

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
           ID   G +   GQLD E  + Y++ V A DGG   ++                       
Sbjct: 289 IDENYGEISVIGQLDHEKASSYEVEVQAEDGGG--QTGHCKVVIEIDDVNDNAPVISVKS 346

Query: 371 YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQ-NGRGLITVAQ 427
            + ++ E+  PGT +  +   D D  E++R+   I+       F +        ++T + 
Sbjct: 347 LKNKIPENTTPGTEIAVINVKDQDSGENSRISCSISPNLP---FQLQPYIKSYFILTTSS 403

Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAMVQINI--TDANNYAPVFENAPYTASVFEDAPIG 485
            LD +Q   Y +T+ ATD G     + + +NI  +D N+ +P FE   Y   + E+   G
Sbjct: 404 SLDREQIDNYNVTIIATDGGIPPLFSNISLNIQVSDVNDNSPRFELHSYFIYISENKQAG 463

Query: 486 TTVLVVSATDSDVGINAQITYSL-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
           T+V  VSA D D   N  + YSL  SE++   ++       IN  TG I T +  D E  
Sbjct: 464 TSVCSVSANDPDWRQNGTVLYSLVPSEVNGVPMSSF---LSINGDTGVIHTVRSFDYEQF 520

Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF------KQQLYTANIMEDALVGT 598
             + + V ARD G P LS    V++ + D NDN P         + L T  + +  L G+
Sbjct: 521 RNFSVKVVARDNGSPPLSSNVTVKVFITDENDNSPQILYPVPDGKSLMTEMVPKATLSGS 580

Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
            VS+V A DAD G N  + Y++  K  + G F I   SG I+T + +        +L   
Sbjct: 581 LVSKVIAVDADSGQNAWLSYQI-LKSTDPGLFTIGLHSGEIKTQRDISESDNMKQNLVIS 639

Query: 659 AIDGGTPPQSSTVIVHIKIED 679
             D G P  S+T +V++ I D
Sbjct: 640 VKDNGQPSLSTTCVVNLLISD 660



 Score =  209 bits (511), Expect = 7e-52
 Identities = 171/605 (28%), Positives = 281/605 (46%), Gaps = 57/605 (9%)

Query: 4   PFCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
           P  +H   + V D ND+ PVF     +  + EGA +G+ +   +A D D+G N+   Y +
Sbjct: 110 PLELHNIALEVQDVNDNPPVFPKGSIKLEISEGAPTGSKLQLTRARDLDVGINSVQTYIL 169

Query: 63  ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122
                  L+ + +           +D + +D     ++ + SLDRE    +++++ A D 
Sbjct: 170 SQNKHFVLDTKSS-----------KDRY-VD-----IVLKNSLDRETRGEHSLILSAVDG 212

Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
            +P +   S T  I V +ID NDN P FS+  Y   + E+ ++  +  + KI ATD D G
Sbjct: 213 GNPPN---SGTVVIEVVVIDMNDNAPLFSQPLYNARLSENSALGTS--VIKITATDEDEG 267

Query: 183 ANSAIRYAI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240
           AN  I+Y I  +  NT+  F ID   G++S++  LD+E+  SY + ++A+DGG   ++  
Sbjct: 268 ANGEIKYYINHLSDNTKQLFKIDENYGEISVIGQLDHEKASSYEVEVQAEDGG--GQTGH 325

Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
            +++I I DVNDNAP       +  + EN   G  I  +   D D G N+ ++ +++   
Sbjct: 326 CKVVIEIDDVNDNAPVISVKSLKNKIPENTTPGTEIAVINVKDQDSGENSRISCSISP-- 383

Query: 301 YTGNVDLPITIDP--RSGWVY-TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357
                +LP  + P  +S ++  TS  LDRE    Y + + ATDGG PP  +  +      
Sbjct: 384 -----NLPFQLQPYIKSYFILTTSSSLDREQIDNYNVTIIATDGGIPPLFSNISLNIQVS 438

Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRG--RFS 413
                   F    Y + ++E++  GT V +++A D D  ++  + Y +      G    S
Sbjct: 439 DVNDNSPRFELHSYFIYISENKQAGTSVCSVSANDPDWRQNGTVLYSLVPSEVNGVPMSS 498

Query: 414 ITSQNG-RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAP-VF 469
             S NG  G+I   +  D++Q R + + V A D+G    S    V++ ITD N+ +P + 
Sbjct: 499 FLSINGDTGVIHTVRSFDYEQFRNFSVKVVARDNGSPPLSSNVTVKVFITDENDNSPQIL 558

Query: 470 ENAPYTASVF-EDAP----IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524
              P   S+  E  P     G+ V  V A D+D G NA ++Y +               F
Sbjct: 559 YPVPDGKSLMTEMVPKATLSGSLVSKVIAVDADSGQNAWLSYQILKSTD-------PGLF 611

Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584
            I   +G I T + +         L ++ +D G PSLS T  V + + D     P  K  
Sbjct: 612 TIGLHSGEIKTQRDISESDNMKQNLVISVKDNGQPSLSTTCVVNLLISDNLSEVPELKDM 671

Query: 585 LYTAN 589
            Y  N
Sbjct: 672 SYEDN 676



 Score =  206 bits (502), Expect = 9e-51
 Identities = 163/573 (28%), Positives = 260/573 (45%), Gaps = 26/573 (4%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQNGRGL-I 423
           F  G  ++E++E  P G+ +    A D D   N +   I   N        S   R + I
Sbjct: 130 FPKGSIKLEISEGAPTGSKLQLTRARDLDVGINSVQTYILSQNKHFVLDTKSSKDRYVDI 189

Query: 424 TVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFED 481
            +   LD +    + L +SA D G    S T ++++ + D N+ AP+F    Y A + E+
Sbjct: 190 VLKNSLDRETRGEHSLILSAVDGGNPPNSGTVVIEVVVIDMNDNAPLFSQPLYNARLSEN 249

Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
           + +GT+V+ ++ATD D G N +I Y ++    N       Q F I+   G I+    LD 
Sbjct: 250 SALGTSVIKITATDEDEGANGEIKYYINHLSDNTK-----QLFKIDENYGEISVIGQLDH 304

Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
           E  S Y + V A DGG    +    V I + DVNDN PV   +     I E+   GT ++
Sbjct: 305 EKASSYEVEVQAEDGG--GQTGHCKVVIEIDDVNDNAPVISVKSLKNKIPENTTPGTEIA 362

Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
            +   D D G N RI   + P    +    I  +  ++ T+ +LDRE +  +++  +A D
Sbjct: 363 VINVKDQDSGENSRISCSISPNLPFQLQPYIK-SYFILTTSSSLDREQIDNYNVTIIATD 421

Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
           GG PP  S + ++I++ D+ND+ P FE      YISEN   GT++  + A+DPD   N  
Sbjct: 422 GGIPPLFSNISLNIQVSDVNDNSPRFELHSYFIYISENKQAGTSVCSVSANDPDWRQNGT 481

Query: 722 VHYSIKGGD-DSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIR-AASPPLWNDV 778
           V YS+   + +    S       D   + T+   DYE  R    ++V R   SPPL ++V
Sbjct: 482 VLYSLVPSEVNGVPMSSFLSINGDTGVIHTVRSFDYEQFRNFSVKVVARDNGSPPLSSNV 541

Query: 779 RVEILVTDVNDNAP----VMKDFQIIFNNY--KDCFPVGPFGRVPAYDADVTDK--LQYR 830
            V++ +TD NDN+P     + D + +      K         +V A DAD      L Y+
Sbjct: 542 TVKVFITDENDNSPQILYPVPDGKSLMTEMVPKATLSGSLVSKVIAVDADSGQNAWLSYQ 601

Query: 831 ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEE 890
           IL   +  L  +   +G +     ++ +      + +SV D   +        V L+  +
Sbjct: 602 ILKSTDPGLFTIGLHSGEIKTQRDISESDNMKQNLVISVKDN-GQPSLSTTCVVNLLISD 660

Query: 891 MLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAI 923
            L  S    L DM+ E   S L  + I  L ++
Sbjct: 661 NL--SEVPELKDMSYEDNNSKLTSYLIIALVSV 691



 Score =  171 bits (416), Expect = 2e-40
 Identities = 118/342 (34%), Positives = 171/342 (50%), Gaps = 16/342 (4%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           + + + D N+  PVF        + E AP G+ + +  A D DVGIN+  TY LS     
Sbjct: 116 IALEVQDVNDNPPVFPKGSIKLEISEGAPTGSKLQLTRARDLDVGINSVQTYILSQNKHF 175

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
                  +   ++     I     LDRET   + L ++A DGG P  S T  +E+ V+D+
Sbjct: 176 VLDTKSSKDRYVD-----IVLKNSLDRETRGEHSLILSAVDGGNPPNSGTVVIEVVVIDM 230

Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP-KDREEGSFVID 633
           NDN P+F Q LY A + E++ +GTSV ++ ATD D G NG I Y ++   D  +  F ID
Sbjct: 231 NDNAPLFSQPLYNARLSENSALGTSVIKITATDEDEGANGEIKYYINHLSDNTKQLFKID 290

Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693
              G I     LD E  ++++++  A DGG   Q+    V I+I+D+ND+ PV     L 
Sbjct: 291 ENYGEISVIGQLDHEKASSYEVEVQAEDGG--GQTGHCKVVIEIDDVNDNAPVISVKSLK 348

Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753
             I EN+  GT I  I   D D G N+ +  SI     +  F L+    S    L T   
Sbjct: 349 NKIPENTTPGTEIAVINVKDQDSGENSRISCSI---SPNLPFQLQPYIKS-YFILTTSSS 404

Query: 754 LDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAP 792
           LD E     Y + I A     PPL++++ + I V+DVNDN+P
Sbjct: 405 LDREQ-IDNYNVTIIATDGGIPPLFSNISLNIQVSDVNDNSP 445



 Score =  123 bits (296), Expect = 8e-26
 Identities = 87/278 (31%), Positives = 135/278 (48%), Gaps = 18/278 (6%)

Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584
           I+  +G +  ++ +DRE + G         +  + +  +  ++ + V DVNDN PVF + 
Sbjct: 74  IDLDSGDLFVSERIDREMLCGTASPCIMHFEFILENPLELHNIALEVQDVNDNPPVFPKG 133

Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR---- 640
                I E A  G+ +    A D DVG+N    Y L     +   FV+D  S   R    
Sbjct: 134 SIKLEISEGAPTGSKLQLTRARDLDVGINSVQTYILS----QNKHFVLDTKSSKDRYVDI 189

Query: 641 -TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699
               +LDRE+   H L   A+DGG PP S TV++ + + D+ND+ P+F        +SEN
Sbjct: 190 VLKNSLDRETRGEHSLILSAVDGGNPPNSGTVVIEVVVIDMNDNAPLFSQPLYNARLSEN 249

Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS--FSLETRQGSDKAELVTMVDLDYE 757
           S +GT++ +I A D DEG N  + Y I    D+    F ++   G    E+  +  LD+E
Sbjct: 250 SALGTSVIKITATDEDEGANGEIKYYINHLSDNTKQLFKIDENYG----EISVIGQLDHE 305

Query: 758 SPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAPVM 794
                YE+ ++A          +V I + DVNDNAPV+
Sbjct: 306 K-ASSYEVEVQAEDGGGQTGHCKVVIEIDDVNDNAPVI 342



 Score = 95.1 bits (226), Expect = 2e-17
 Identities = 76/268 (28%), Positives = 118/268 (44%), Gaps = 25/268 (9%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           I   I V D ND+SP FE+  Y   + E   +GT+V ++ A D D  +N  V Y+     
Sbjct: 431 ISLNIQVSDVNDNSPRFELHSYFIYISENKQAGTSVCSVSANDPDWRQNGTVLYS----- 485

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
              L P +           +     I+G +G + T  S D E+   ++V V A D  SP 
Sbjct: 486 ---LVPSEVNGVP------MSSFLSINGDTGVIHTVRSFDYEQFRNFSVKVVARDNGSPP 536

Query: 127 SDRLSSTATIHVNIIDDNDNYPQF------SEKTYTVSVDEDISVTDNPVIAKIKATDAD 180
              LSS  T+ V I D+NDN PQ        +   T  V +  +     +++K+ A DAD
Sbjct: 537 ---LSSNVTVKVFITDENDNSPQILYPVPDGKSLMTEMVPK--ATLSGSLVSKVIAVDAD 591

Query: 181 VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240
            G N+ + Y I+       F+I   SG++   + +         LVI  +D G PS S T
Sbjct: 592 SGQNAWLSYQILKSTDPGLFTIGLHSGEIKTQRDISESDNMKQNLVISVKDNGQPSLSTT 651

Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSE 268
             + + I D     P      ++++ S+
Sbjct: 652 CVVNLLISDNLSEVPELKDMSYEDNNSK 679


>UniRef50_P73089 Cluster: Fat protein; n=1; Synechocystis sp. PCC
            6803|Rep: Fat protein - Synechocystis sp. (strain PCC
            6803)
          Length = 1965

 Score =  214 bits (522), Expect = 3e-53
 Identities = 201/789 (25%), Positives = 355/789 (44%), Gaps = 41/789 (5%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            F + G+S  L     L+ E  A YTV V   D     +  L++   + +N +D+    P 
Sbjct: 684  FEVIGQSLFLKAGTVLNFESKASYTVTVNVDDDTVGSTPDLTADFKLTINNLDEVA--PT 741

Query: 150  FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209
             +      ++ E+     N +I ++KATD D   ++ I + +  G+    F I++ +G+V
Sbjct: 742  ITSGDTAKAIAENSGA--NQIIYQVKATD-DGDISAGITFGLKPGDDADSFIINATTGEV 798

Query: 210  SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIRDVNDNAPRFYTSLFQESVSE 268
             L+   D+E   SY+  + A DG +P+   T QL+ + I D+++ AP   +    ++++E
Sbjct: 799  KLIGNPDFETQSSYKFTVTADDGVNPA---TEQLVNLAIIDLDEIAPTITSGDTAKAIAE 855

Query: 269  NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328
            N      I +V A D D  V+A +T+ +   +   + DL I I+  +G V  +   D ET
Sbjct: 856  NSGANQVIYQVTATD-DADVSAGITFGLKPGN---DADLFI-INSTTGQVILTENPDFET 910

Query: 329  QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388
            Q+ Y+  VTA+DG +P      T                 G     + E+      +  +
Sbjct: 911  QSSYKFTVTASDGVNPATEKIVT--LAIIDLDEIAPTITSGDTAKAITENSGANQVIYEV 968

Query: 389  TAT-DADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447
             AT DAD    + + +  GN  G F+I    G+  +T+    DF+ +  Y  TV+A+D  
Sbjct: 969  IATDDADVSAGITFGLKPGNDAGSFTINPITGK--VTLIDDPDFETQSSYKFTVTASDGV 1026

Query: 448  GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507
              +   +V + I D +  AP   +     ++ E++     +  V ATD D  ++A IT+ 
Sbjct: 1027 NLATEQLVNLTIIDLDEIAPTITSGDTAKAIAENSGANQVIYEVIATD-DADVSAGITFG 1085

Query: 508  LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567
            L     N+A       F INP TG +T     D ET S Y  TVTA DG   +L+    V
Sbjct: 1086 LKP--GNDA-----GSFTINPITGKVTLIDDPDFETQSSYKFTVTASDG--VNLATEQLV 1136

Query: 568  EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627
             ++++D+++  P          I E++     + Q  A D +  ++  + + L P D + 
Sbjct: 1137 NLTIIDLDEIAPTITSGDTAKAITENSGANQIIYQATADD-NADISAGVTFGLKPGD-DA 1194

Query: 628  GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687
             SF+I+  +G +      D E+ +++     A DG  P      +V++ I D+++  P  
Sbjct: 1195 DSFIINAITGQVTLLDNPDFETQSSYKFTVTASDGVNPVTEQ--VVNLTIIDLDEIAPTI 1252

Query: 688  ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747
             S      I+ENS     I ++ A D D   +A V + +K GDD+ SFS+++  G  K  
Sbjct: 1253 TSGNTAKAIAENSGANQVIYQVTATD-DADISAEVTFGLKLGDDATSFSIDSTTG--KVT 1309

Query: 748  LVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMK--DFQIIFNNYK 805
            L+   D + +S  K         +P    +  V + + ++++  P +   D     +   
Sbjct: 1310 LINNPDFESQSSYKFTVTASDGVNPA--TEKIVTLAINNLDEIGPTITSGDTATPIDENS 1367

Query: 806  DCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATM 865
                +  +  +   DADV+  + + +  GN+A    +N  TG +TL    +         
Sbjct: 1368 GANQL-IYQVIATDDADVSAGITFGLKPGNDAGSFTINPITGEVTLIDDPDFETQSSYKF 1426

Query: 866  EVSVTDGVN 874
             V+ +DGVN
Sbjct: 1427 TVTASDGVN 1435



 Score =  210 bits (513), Expect = 4e-52
 Identities = 213/861 (24%), Positives = 392/861 (45%), Gaps = 49/861 (5%)

Query: 43   LTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR 102
            +T   T + I +N+     I  VTA       A            D+F I+  +G ++  
Sbjct: 844  ITSGDTAKAIAENSGANQVIYQVTATDDADVSAGITFGLKPGNDADLFIINSTTGQVILT 903

Query: 103  ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162
             + D E  + Y   V A+D  +P ++++ + A     IID ++  P  +      ++ E+
Sbjct: 904  ENPDFETQSSYKFTVTASDGVNPATEKIVTLA-----IIDLDEIAPTITSGDTAKAITEN 958

Query: 163  ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222
                 N VI ++ ATD D   ++ I + +  GN    F+I+ ++G V+L+   D+E   S
Sbjct: 959  SGA--NQVIYEVIATD-DADVSAGITFGLKPGNDAGSFTINPITGKVTLIDDPDFETQSS 1015

Query: 223  YRLVIRAQDGGSPSRSNTTQLL-INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA 281
            Y+  + A DG + +   T QL+ + I D+++ AP   +    ++++EN      I  V A
Sbjct: 1016 YKFTVTASDGVNLA---TEQLVNLTIIDLDEIAPTITSGDTAKAIAENSGANQVIYEVIA 1072

Query: 282  YDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341
             D D  V+A +T+ +   +  G+     TI+P +G V      D ETQ+ Y+  VTA+DG
Sbjct: 1073 TD-DADVSAGITFGLKPGNDAGS----FTINPITGKVTLIDDPDFETQSSYKFTVTASDG 1127

Query: 342  GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD-ADEDNRLH 400
             +   +                     G     + E+      +   TA D AD    + 
Sbjct: 1128 VN--LATEQLVNLTIIDLDEIAPTITSGDTAKAITENSGANQIIYQATADDNADISAGVT 1185

Query: 401  YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT 460
            + +  G+    F I +  G+  +T+    DF+ +  Y  TV+A+D        +V + I 
Sbjct: 1186 FGLKPGDDADSFIINAITGQ--VTLLDNPDFETQSSYKFTVTASDGVNPVTEQVVNLTII 1243

Query: 461  DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520
            D +  AP   +     ++ E++     +  V+ATD D  I+A++T+ L  ++ ++A +  
Sbjct: 1244 DLDEIAPTITSGNTAKAIAENSGANQVIYQVTATD-DADISAEVTFGL--KLGDDATS-- 1298

Query: 521  DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580
               F I+  TG +T     D E+ S Y  TVTA DG  P+      V +++ ++++  P 
Sbjct: 1299 ---FSIDSTTGKVTLINNPDFESQSSYKFTVTASDGVNPATEKI--VTLAINNLDEIGPT 1353

Query: 581  FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640
                     I E++     + QV ATD D  ++  I + L P + + GSF I+P +G + 
Sbjct: 1354 ITSGDTATPIDENSGANQLIYQVIATD-DADVSAGITFGLKPGN-DAGSFTINPITGEVT 1411

Query: 641  TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700
                 D E+ +++     A DG  P  ++  IV + I D+++  P   SD +   I+ENS
Sbjct: 1412 LIDDPDFETQSSYKFTVTASDGVNP--ATEKIVTLTINDLDELGPNITSDNIATAINENS 1469

Query: 701  PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDL-DYESP 759
                 I ++ A D D+  +A V + +K GD++N FS++   G      VT++D  D+E+ 
Sbjct: 1470 GANQIIYQVTADDGDD-ISAGVTFGLKPGDNANQFSIDPTTGQ-----VTLLDNPDFET- 1522

Query: 760  RKKYELVIRAASP--PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVP 817
            +  Y+  + A+    P    + V + + D+++ AP +          ++        +V 
Sbjct: 1523 QSSYKFTVTASDGVNPATEQL-VNLTIIDLDEIAPTITSGDTAKAIAENSGANQVIYQVT 1581

Query: 818  AYD-ADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEI 876
            A D AD +  + + +  G +AN   +N  TG + L    +          V+ +DGVN +
Sbjct: 1582 ATDDADTSAGVTFGLKPGEDANSFTINAATGEVELIGNPDFETQSSYKFTVTASDGVNPV 1641

Query: 877  KAMMQLSVRLITEEMLLNSIT 897
               + +++ +I  + +  +IT
Sbjct: 1642 TEQV-VNLTIIDLDEIAPTIT 1661



 Score =  209 bits (511), Expect = 7e-52
 Identities = 201/792 (25%), Positives = 355/792 (44%), Gaps = 46/792 (5%)

Query: 88   DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
            D F I+  +G +    + D E  + Y   V A D  +P +++L     +++ IID ++  
Sbjct: 787  DSFIINATTGEVKLIGNPDFETQSSYKFTVTADDGVNPATEQL-----VNLAIIDLDEIA 841

Query: 148  PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
            P  +      ++ E+     N VI ++ ATD D   ++ I + +  GN    F I+S +G
Sbjct: 842  PTITSGDTAKAIAENSGA--NQVIYQVTATD-DADVSAGITFGLKPGNDADLFIINSTTG 898

Query: 208  DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
             V L +  D+E   SY+  + A DG +P+      L   I D+++ AP   +    ++++
Sbjct: 899  QVILTENPDFETQSSYKFTVTASDGVNPATEKIVTLA--IIDLDEIAPTITSGDTAKAIT 956

Query: 268  ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
            EN      I  V A D D  V+A +T+ +   +  G+     TI+P +G V      D E
Sbjct: 957  ENSGANQVIYEVIATD-DADVSAGITFGLKPGNDAGS----FTINPITGKVTLIDDPDFE 1011

Query: 328  TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387
            TQ+ Y+  VTA+DG +   +                     G     +AE+      +  
Sbjct: 1012 TQSSYKFTVTASDGVN--LATEQLVNLTIIDLDEIAPTITSGDTAKAIAENSGANQVIYE 1069

Query: 388  LTAT-DADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446
            + AT DAD    + + +  GN  G F+I    G+  +T+    DF+ +  Y  TV+A+D 
Sbjct: 1070 VIATDDADVSAGITFGLKPGNDAGSFTINPITGK--VTLIDDPDFETQSSYKFTVTASDG 1127

Query: 447  GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT-DSDVGINAQIT 505
               +   +V + I D +  AP   +     ++ E++  G   ++  AT D +  I+A +T
Sbjct: 1128 VNLATEQLVNLTIIDLDEIAPTITSGDTAKAITENS--GANQIIYQATADDNADISAGVT 1185

Query: 506  YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTT 565
            + L     ++A       F+IN  TG +T     D ET S Y  TVTA DG  P      
Sbjct: 1186 FGLKP--GDDA-----DSFIINAITGQVTLLDNPDFETQSSYKFTVTASDGVNPVTEQV- 1237

Query: 566  DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625
             V ++++D+++  P          I E++     + QV ATD D  ++  + + L   D 
Sbjct: 1238 -VNLTIIDLDEIAPTITSGNTAKAIAENSGANQVIYQVTATD-DADISAEVTFGLKLGD- 1294

Query: 626  EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685
            +  SF ID  +G +      D ES +++     A DG  P  ++  IV + I ++++  P
Sbjct: 1295 DATSFSIDSTTGKVTLINNPDFESQSSYKFTVTASDGVNP--ATEKIVTLAINNLDEIGP 1352

Query: 686  VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745
               S      I ENS     I ++ A D D   +A + + +K G+D+ SF++    G   
Sbjct: 1353 TITSGDTATPIDENSGANQLIYQVIATD-DADVSAGITFGLKPGNDAGSFTINPITG--- 1408

Query: 746  AELVTMVDLDYESPRKKYELVIRAAS--PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN 803
             E+  + D D+E+ +  Y+  + A+    P    + V + + D+++  P +    I    
Sbjct: 1409 -EVTLIDDPDFET-QSSYKFTVTASDGVNPATEKI-VTLTINDLDELGPNITSDNIATAI 1465

Query: 804  YKDCFPVGPFGRVPAYDA-DVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKL 862
             ++        +V A D  D++  + + +  G+NAN   ++ TTG +TL    +      
Sbjct: 1466 NENSGANQIIYQVTADDGDDISAGVTFGLKPGDNANQFSIDPTTGQVTLLDNPDFETQSS 1525

Query: 863  ATMEVSVTDGVN 874
                V+ +DGVN
Sbjct: 1526 YKFTVTASDGVN 1537



 Score =  202 bits (492), Expect = 1e-49
 Identities = 198/805 (24%), Positives = 362/805 (44%), Gaps = 43/805 (5%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            F I+  +G +      D E  + Y   V A+D  +  +++L     +++ IID ++  P 
Sbjct: 993  FTINPITGKVTLIDDPDFETQSSYKFTVTASDGVNLATEQL-----VNLTIIDLDEIAPT 1047

Query: 150  FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209
             +      ++ E+     N VI ++ ATD D   ++ I + +  GN    F+I+ ++G V
Sbjct: 1048 ITSGDTAKAIAENSGA--NQVIYEVIATD-DADVSAGITFGLKPGNDAGSFTINPITGKV 1104

Query: 210  SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIRDVNDNAPRFYTSLFQESVSE 268
            +L+   D+E   SY+  + A DG + +   T QL+ + I D+++ AP   +    ++++E
Sbjct: 1105 TLIDDPDFETQSSYKFTVTASDGVNLA---TEQLVNLTIIDLDEIAPTITSGDTAKAITE 1161

Query: 269  NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328
            N      I +  A D +  ++A +T+ +   D   +      I+  +G V      D ET
Sbjct: 1162 NSGANQIIYQATA-DDNADISAGVTFGLKPGDDADS----FIINAITGQVTLLDNPDFET 1216

Query: 329  QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388
            Q+ Y+  VTA+DG +P                        G     +AE+      +  +
Sbjct: 1217 QSSYKFTVTASDGVNPVTEQVVNLTIIDLDEIAPTIT--SGNTAKAIAENSGANQVIYQV 1274

Query: 389  TATD-ADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447
            TATD AD    + + +  G+    FSI S  G+  +T+    DF+ +  Y  TV+A+D  
Sbjct: 1275 TATDDADISAEVTFGLKLGDDATSFSIDSTTGK--VTLINNPDFESQSSYKFTVTASDGV 1332

Query: 448  GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507
              +   +V + I + +   P   +      + E++     +  V ATD D  ++A IT+ 
Sbjct: 1333 NPATEKIVTLAINNLDEIGPTITSGDTATPIDENSGANQLIYQVIATD-DADVSAGITFG 1391

Query: 508  LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567
            L     N+A +     F INP TG +T     D ET S Y  TVTA DG  P+      V
Sbjct: 1392 LKP--GNDAGS-----FTINPITGEVTLIDDPDFETQSSYKFTVTASDGVNPATEKI--V 1442

Query: 568  EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627
             +++ D+++  P          I E++     + QV A D D  ++  + + L P D   
Sbjct: 1443 TLTINDLDELGPNITSDNIATAINENSGANQIIYQVTADDGD-DISAGVTFGLKPGDNAN 1501

Query: 628  GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687
              F IDP +G +      D E+ +++     A DG  P  ++  +V++ I D+++  P  
Sbjct: 1502 -QFSIDPTTGQVTLLDNPDFETQSSYKFTVTASDGVNP--ATEQLVNLTIIDLDEIAPTI 1558

Query: 688  ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747
             S      I+ENS     I ++ A D D   +A V + +K G+D+NSF++    G  + E
Sbjct: 1559 TSGDTAKAIAENSGANQVIYQVTATD-DADTSAGVTFGLKPGEDANSFTINAATG--EVE 1615

Query: 748  LVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC 807
            L+   D + +S  K + +       P+   V V + + D+++ AP +          ++ 
Sbjct: 1616 LIGNPDFETQSSYK-FTVTASDGVNPVTEQV-VNLTIIDLDEIAPTITSGNTAKAIAENS 1673

Query: 808  FPVGPFGRVPAYD-ADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATME 866
                   +V A D AD++  + + +  G++A    ++ TTG +TL    +          
Sbjct: 1674 GANQVIYQVTATDDADISAGVTFGLKPGDDATSFSIDSTTGKVTLINNPDFESQSSYRFT 1733

Query: 867  VSVTDGVNEIKAMMQLSVRLITEEM 891
            V+  DGVN +    Q+++ ++ + +
Sbjct: 1734 VTADDGVNPV-TEQQIALEILDDNV 1757



 Score =  192 bits (468), Expect = 1e-46
 Identities = 178/709 (25%), Positives = 316/709 (44%), Gaps = 43/709 (6%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            F I+  +G +      D E  + Y   V A+D  +  +++L     +++ IID ++  P 
Sbjct: 1095 FTINPITGKVTLIDDPDFETQSSYKFTVTASDGVNLATEQL-----VNLTIIDLDEIAPT 1149

Query: 150  FSEKTYTVSVDEDISVTDNPVIAKIKATD-ADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
             +      ++ E+     N +I +  A D AD+ A   + + +  G+    F I++++G 
Sbjct: 1150 ITSGDTAKAITENSGA--NQIIYQATADDNADISAG--VTFGLKPGDDADSFIINAITGQ 1205

Query: 209  VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268
            V+L+   D+E   SY+  + A DG +P       L   I D+++ AP   +    ++++E
Sbjct: 1206 VTLLDNPDFETQSSYKFTVTASDGVNPVTEQVVNL--TIIDLDEIAPTITSGNTAKAIAE 1263

Query: 269  NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328
            N      I +V A D D  ++AE+T+ +      G+     +ID  +G V      D E+
Sbjct: 1264 NSGANQVIYQVTATD-DADISAEVTFGLK----LGDDATSFSIDSTTGKVTLINNPDFES 1318

Query: 329  QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388
            Q+ Y+  VTA+DG +P      T                 G     + E+      +  +
Sbjct: 1319 QSSYKFTVTASDGVNPATEKIVTLAINNLDEIGPTIT--SGDTATPIDENSGANQLIYQV 1376

Query: 389  TATD-ADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447
             ATD AD    + + +  GN  G F+I    G   +T+    DF+ +  Y  TV+A+D  
Sbjct: 1377 IATDDADVSAGITFGLKPGNDAGSFTINPITGE--VTLIDDPDFETQSSYKFTVTASDGV 1434

Query: 448  GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507
              +   +V + I D +   P   +     ++ E++     +  V+A D D  I+A +T+ 
Sbjct: 1435 NPATEKIVTLTINDLDELGPNITSDNIATAINENSGANQIIYQVTADDGD-DISAGVTFG 1493

Query: 508  LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567
            L           +  QF I+P TG +T     D ET S Y  TVTA DG  P+      V
Sbjct: 1494 LKP-------GDNANQFSIDPTTGQVTLLDNPDFETQSSYKFTVTASDGVNPATEQL--V 1544

Query: 568  EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627
             ++++D+++  P          I E++     + QV ATD D   +  + + L P + + 
Sbjct: 1545 NLTIIDLDEIAPTITSGDTAKAIAENSGANQVIYQVTATD-DADTSAGVTFGLKPGE-DA 1602

Query: 628  GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687
             SF I+ A+G +      D E+ +++     A DG  P      +V++ I D+++  P  
Sbjct: 1603 NSFTINAATGEVELIGNPDFETQSSYKFTVTASDGVNPVTEQ--VVNLTIIDLDEIAPTI 1660

Query: 688  ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747
             S      I+ENS     I ++ A D D   +A V + +K GDD+ SFS+++  G  K  
Sbjct: 1661 TSGNTAKAIAENSGANQVIYQVTATD-DADISAGVTFGLKPGDDATSFSIDSTTG--KVT 1717

Query: 748  LVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKD 796
            L+   D + +S  +         +P     + +EIL    +DN  V+++
Sbjct: 1718 LINNPDFESQSSYRFTVTADDGVNPVTEQQIALEIL----DDNVAVIEN 1762



 Score =  173 bits (422), Expect = 4e-41
 Identities = 158/639 (24%), Positives = 275/639 (43%), Gaps = 32/639 (5%)

Query: 43   LTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR 102
            +T   T + I +N+     I   TAD      A            D F I+  +G +   
Sbjct: 1150 ITSGDTAKAITENSGANQIIYQATADDNADISAGVTFGLKPGDDADSFIINAITGQVTLL 1209

Query: 103  ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162
             + D E  + Y   V A+D  +PV++++     +++ IID ++  P  +      ++ E+
Sbjct: 1210 DNPDFETQSSYKFTVTASDGVNPVTEQV-----VNLTIIDLDEIAPTITSGNTAKAIAEN 1264

Query: 163  ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222
                 N VI ++ ATD D   ++ + + +  G+    FSIDS +G V+L+   D+E   S
Sbjct: 1265 SGA--NQVIYQVTATD-DADISAEVTFGLKLGDDATSFSIDSTTGKVTLINNPDFESQSS 1321

Query: 223  YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY 282
            Y+  + A DG +P+      L IN  ++++  P   +      + EN      I +V A 
Sbjct: 1322 YKFTVTASDGVNPATEKIVTLAIN--NLDEIGPTITSGDTATPIDENSGANQLIYQVIAT 1379

Query: 283  DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG 342
            D D  V+A +T+ +   +  G+     TI+P +G V      D ETQ+ Y+  VTA+DG 
Sbjct: 1380 D-DADVSAGITFGLKPGNDAGS----FTINPITGEVTLIDDPDFETQSSYKFTVTASDGV 1434

Query: 343  DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR-LHY 401
            +P      T                       + E+      +  +TA D D+ +  + +
Sbjct: 1435 NPATEKIVT--LTINDLDELGPNITSDNIATAINENSGANQIIYQVTADDGDDISAGVTF 1492

Query: 402  EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITD 461
             +  G+   +FSI    G+  +T+    DF+ +  Y  TV+A+D    +   +V + I D
Sbjct: 1493 GLKPGDNANQFSIDPTTGQ--VTLLDNPDFETQSSYKFTVTASDGVNPATEQLVNLTIID 1550

Query: 462  ANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521
             +  AP   +     ++ E++     +  V+ATD D   +A +T+ L             
Sbjct: 1551 LDEIAPTITSGDTAKAIAENSGANQVIYQVTATD-DADTSAGVTFGLKP-------GEDA 1602

Query: 522  QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581
              F IN  TG +      D ET S Y  TVTA DG  P       V ++++D+++  P  
Sbjct: 1603 NSFTINAATGEVELIGNPDFETQSSYKFTVTASDGVNPVTEQV--VNLTIIDLDEIAPTI 1660

Query: 582  KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641
                    I E++     + QV ATD D  ++  + + L P D +  SF ID  +G +  
Sbjct: 1661 TSGNTAKAIAENSGANQVIYQVTATD-DADISAGVTFGLKPGD-DATSFSIDSTTGKVTL 1718

Query: 642  NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680
                D ES +++     A DG  P     + + I  +++
Sbjct: 1719 INNPDFESQSSYRFTVTADDGVNPVTEQQIALEILDDNV 1757



 Score =  137 bits (332), Expect = 4e-30
 Identities = 139/580 (23%), Positives = 258/580 (44%), Gaps = 31/580 (5%)

Query: 324  LDRETQAKYQLLVTATDG--GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381
            L+ E++A Y + V   D   G  P   TA                  G     +AE+   
Sbjct: 699  LNFESKASYTVTVNVDDDTVGSTP-DLTADFKLTINNLDEVAPTITSGDTAKAIAENSGA 757

Query: 382  GTPVVTLTATD-ADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440
               +  + ATD  D    + + +  G+    F I +  G   + +  P DF+ +  Y  T
Sbjct: 758  NQIIYQVKATDDGDISAGITFGLKPGDDADSFIINATTGEVKL-IGNP-DFETQSSYKFT 815

Query: 441  VSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
            V+A D    +   +V + I D +  AP   +     ++ E++     +  V+ATD D  +
Sbjct: 816  VTADDGVNPATEQLVNLAIIDLDEIAPTITSGDTAKAIAENSGANQVIYQVTATD-DADV 874

Query: 501  NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560
            +A IT+ L     N+A       F+IN  TG +   +  D ET S Y  TVTA DG  P+
Sbjct: 875  SAGITFGLKP--GNDA-----DLFIINSTTGQVILTENPDFETQSSYKFTVTASDGVNPA 927

Query: 561  LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620
                  V ++++D+++  P          I E++     + +V ATD D  ++  I + L
Sbjct: 928  TEKI--VTLAIIDLDEIAPTITSGDTAKAITENSGANQVIYEVIATD-DADVSAGITFGL 984

Query: 621  DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680
             P + + GSF I+P +G +      D E+ +++     A DG     ++  +V++ I D+
Sbjct: 985  KPGN-DAGSFTINPITGKVTLIDDPDFETQSSYKFTVTASDGVN--LATEQLVNLTIIDL 1041

Query: 681  NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR 740
            ++  P   S      I+ENS     I E+ A D D   +A + + +K G+D+ SF++   
Sbjct: 1042 DEIAPTITSGDTAKAIAENSGANQVIYEVIATD-DADVSAGITFGLKPGNDAGSFTINPI 1100

Query: 741  QGSDKAELVTMVD-LDYESPRKKYELVIRAASPP-LWNDVRVEILVTDVNDNAPVMKDFQ 798
             G      VT++D  D+E+ +  Y+  + A+    L  +  V + + D+++ AP +    
Sbjct: 1101 TGK-----VTLIDDPDFET-QSSYKFTVTASDGVNLATEQLVNLTIIDLDEIAPTITSGD 1154

Query: 799  IIFNNYKDCFPVGPFGRVPAYD-ADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNT 857
                  ++        +  A D AD++  + + +  G++A+  ++N  TG +TL    + 
Sbjct: 1155 TAKAITENSGANQIIYQATADDNADISAGVTFGLKPGDDADSFIINAITGQVTLLDNPDF 1214

Query: 858  NVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSIT 897
                     V+ +DGVN +   + +++ +I  + +  +IT
Sbjct: 1215 ETQSSYKFTVTASDGVNPVTEQV-VNLTIIDLDEIAPTIT 1253


>UniRef50_UPI0000E80EB2 Cluster: PREDICTED: hypothetical protein;
           n=1; Gallus gallus|Rep: PREDICTED: hypothetical protein
           - Gallus gallus
          Length = 1259

 Score =  213 bits (521), Expect = 4e-53
 Identities = 166/584 (28%), Positives = 268/584 (45%), Gaps = 27/584 (4%)

Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195
           + V ++D ND+ P F  + Y + V E  S           A D DVG NS   Y +   N
Sbjct: 420 VEVEVLDINDHAPTFPWQEYVLEVAE--SAVLGARFPLESAQDPDVGTNSVHTYQL-SPN 476

Query: 196 TQMQFSIDSLS-----GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
           +     + + S      ++ L + LD EQ R++RL++ A DGG P RS T  +L+ + D 
Sbjct: 477 SFFSLEVHTRSDASKFAELVLERALDREQQRTHRLLLTALDGGIPRRSGTAHVLVTVLDA 536

Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
           NDN P F    +  S+ E+ P G  ++++ A D DEG N E+ Y+ +        +L   
Sbjct: 537 NDNIPAFDQPSYGVSLPEDAPAGTLVIQLNATDLDEGPNGEIEYSFSGHAPPSVREL-FR 595

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
           ++PRSG V   G LD E  + ++L V A D G    +                       
Sbjct: 596 VEPRSGQVLLKGPLDYERASLHELYVQAKDRGPSAVAVHCRVLVHLLDVNDNAPEVTLTS 655

Query: 371 YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
               + ED PPGT +  ++  D D  ++ R+  E++  +       + ++   L+T  +P
Sbjct: 656 VSTPVQEDAPPGTVIAVISVLDRDSGDNGRVSCELS-PSVPFELRSSFRDYYTLVT-TEP 713

Query: 429 LDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
           LD +    Y ++++A D G  +    + + + ++D N+ AP F    Y+  V E+   G 
Sbjct: 714 LDREAVSEYNISITARDMGSPALLTRSTLTVPVSDVNDNAPHFLQPSYSVYVMENNAPGA 773

Query: 487 TVLVVSATDSDVGINAQITYSLS-SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
           ++  VSA D D   NA ++YS++   I    V  +     IN  +G +   + LD E + 
Sbjct: 774 SICSVSALDPDCQQNAYLSYSITDGHIHGMPVGTY---VSINSDSGHMYALRSLDYEQIR 830

Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF------KQQLYTANIMEDALVGTS 599
            + + V A+D G P LS    V I V+D NDN PV          + T  +   A  G  
Sbjct: 831 SFQIQVQAQDAGFPPLSANVTVHIFVLDQNDNAPVIVSPMPRNGSVATELVPRSAGPGYL 890

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
           V  V A DAD GLN R+ Y+L  +  +   F + P +G +RT ++   +  A   L    
Sbjct: 891 VGTVSAVDADAGLNSRLSYQL-LQATDFTLFSLAPDTGELRTLRSFLEQDAARQRLVVQV 949

Query: 660 IDGGTPPQSSTVIVHIK-IEDINDSPPVFESDCLTFYISENSPI 702
            DGG P  S+TV + +  +E +  +   F +  L    S +SP+
Sbjct: 950 RDGGQPALSATVSLLLSVVETMPQTLSDFSNFSLPPEASSSSPL 993



 Score =  209 bits (511), Expect = 7e-52
 Identities = 169/583 (28%), Positives = 264/583 (45%), Gaps = 53/583 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ VLD NDH+P F  Q+Y   V E A  G       A D D+G N+   Y         
Sbjct: 421 EVEVLDINDHAPTFPWQEYVLEVAESAVLGARFPLESAQDPDVGTNSVHTYQ-------- 472

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
           L+P                      +   L+   +LDRE+   + +L+ A D   P   R
Sbjct: 473 LSPNSFFSLEVHTRSDAS-------KFAELVLERALDREQQRTHRLLLTALDGGIP---R 522

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            S TA + V ++D NDN P F + +Y VS+ ED       ++ ++ ATD D G N  I Y
Sbjct: 523 RSGTAHVLVTVLDANDNIPAFDQPSYGVSLPEDAPA--GTLVIQLNATDLDEGPNGEIEY 580

Query: 190 AIIG---GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           +  G    + +  F ++  SG V L   LDYE+   + L ++A+D G  + +   ++L++
Sbjct: 581 SFSGHAPPSVRELFRVEPRSGQVLLKGPLDYERASLHELYVQAKDRGPSAVAVHCRVLVH 640

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
           + DVNDNAP    +     V E+ P G  I  +   D D G N  ++  ++      +V 
Sbjct: 641 LLDVNDNAPEVTLTSVSTPVQEDAPPGTVIAVISVLDRDSGDNGRVSCELSP-----SVP 695

Query: 307 LPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
             +    R  + + T+  LDRE  ++Y + +TA D G P     +T              
Sbjct: 696 FELRSSFRDYYTLVTTEPLDREAVSEYNISITARDMGSPALLTRSTLTVPVSDVNDNAPH 755

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGR-----FSITSQN 418
           F+   Y V + E+  PG  + +++A D D  ++  L Y IT G+  G       SI S +
Sbjct: 756 FLQPSYSVYVMENNAPGASICSVSALDPDCQQNAYLSYSITDGHIHGMPVGTYVSINSDS 815

Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFEN-APYT 475
           G   +   + LD++Q R + + V A D+G    S    V I + D N+ APV  +  P  
Sbjct: 816 GH--MYALRSLDYEQIRSFQIQVQAQDAGFPPLSANVTVHIFVLDQNDNAPVIVSPMPRN 873

Query: 476 ASVFED-----APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
            SV  +     A  G  V  VSA D+D G+N++++Y L         A     F + P T
Sbjct: 874 GSVATELVPRSAGPGYLVGTVSAVDADAGLNSRLSYQLLQ-------ATDFTLFSLAPDT 926

Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
           G + T +    +  +   L V  RDGG P+LS T  + +SVV+
Sbjct: 927 GELRTLRSFLEQDAARQRLVVQVRDGGQPALSATVSLLLSVVE 969



 Score =  194 bits (474), Expect = 2e-47
 Identities = 158/522 (30%), Positives = 245/522 (46%), Gaps = 26/522 (4%)

Query: 370 QYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQNGRGL---ITV 425
           +Y +E+AE    G      +A D D   N +H      N+     + +++       + +
Sbjct: 438 EYVLEVAESAVLGARFPLESAQDPDVGTNSVHTYQLSPNSFFSLEVHTRSDASKFAELVL 497

Query: 426 AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
            + LD +Q+R + L ++A D G   RS TA V + + DAN+  P F+   Y  S+ EDAP
Sbjct: 498 ERALDREQQRTHRLLLTALDGGIPRRSGTAHVLVTVLDANDNIPAFDQPSYGVSLPEDAP 557

Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
            GT V+ ++ATD D G N +I YS S      A     + F + P++G +     LD E 
Sbjct: 558 AGTLVIQLNATDLDEGPNGEIEYSFSGH----APPSVRELFRVEPRSGQVLLKGPLDYER 613

Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
            S + L V A+D G  +++    V + ++DVNDN P       +  + EDA  GT ++ +
Sbjct: 614 ASLHELYVQAKDRGPSAVAVHCRVLVHLLDVNDNAPEVTLTSVSTPVQEDAPPGTVIAVI 673

Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
              D D G NGR+  EL P    E          ++ T + LDRE+V+ +++   A D G
Sbjct: 674 SVLDRDSGDNGRVSCELSPSVPFELRSSFRDYYTLV-TTEPLDREAVSEYNISITARDMG 732

Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
           +P   +   + + + D+ND+ P F     + Y+ EN+  G +I  + A DPD   NA + 
Sbjct: 733 SPALLTRSTLTVPVSDVNDNAPHFLQPSYSVYVMENNAPGASICSVSALDPDCQQNAYLS 792

Query: 724 YSIKGGD-DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVR 779
           YSI  G              SD   +  +  LDYE  R  +++ ++A     PPL  +V 
Sbjct: 793 YSITDGHIHGMPVGTYVSINSDSGHMYALRSLDYEQIR-SFQIQVQAQDAGFPPLSANVT 851

Query: 780 VEILVTDVNDNAPV-MKDFQIIFNNYKDCFP--VGP---FGRVPAYDAD--VTDKLQYRI 831
           V I V D NDNAPV +       +   +  P   GP    G V A DAD  +  +L Y++
Sbjct: 852 VHIFVLDQNDNAPVIVSPMPRNGSVATELVPRSAGPGYLVGTVSAVDADAGLNSRLSYQL 911

Query: 832 LSGNNANLILLNETTGSM-TLSPQLNTNVPKLATMEVSVTDG 872
           L   +  L  L   TG + TL   L  +  +   + V V DG
Sbjct: 912 LQATDFTLFSLAPDTGELRTLRSFLEQDAAR-QRLVVQVRDG 952



 Score =  173 bits (420), Expect = 8e-41
 Identities = 152/486 (31%), Positives = 220/486 (45%), Gaps = 45/486 (9%)

Query: 8   HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
           H  + VLD ND+ P F+   Y  S+ E A +GT V+ L ATD D G N E+EY+      
Sbjct: 528 HVLVTVLDANDNIPAFDQPSYGVSLPEDAPAGTLVIQLNATDLDEGPNGEIEYSFS---- 583

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
                             V+++FR++ RSG +L +  LD E+ + + + V+A D+  P +
Sbjct: 584 ------------GHAPPSVRELFRVEPRSGQVLLKGPLDYERASLHELYVQAKDR-GPSA 630

Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
             +     +H  ++D NDN P+ +  + +  V ED       VIA I   D D G N  +
Sbjct: 631 VAVHCRVLVH--LLDVNDNAPEVTLTSVSTPVQED--APPGTVIAVISVLDRDSGDNGRV 686

Query: 188 RYAIIGGNTQMQFSIDSLSGD-VSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
              +   +  + F + S   D  +LV T  LD E V  Y + I A+D GSP+    + L 
Sbjct: 687 SCEL---SPSVPFELRSSFRDYYTLVTTEPLDREAVSEYNISITARDMGSPALLTRSTLT 743

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG- 303
           + + DVNDNAP F    +   V EN   G SI  V A D D   NA L+Y++TD    G 
Sbjct: 744 VPVSDVNDNAPHFLQPSYSVYVMENNAPGASICSVSALDPDCQQNAYLSYSITDGHIHGM 803

Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
            V   ++I+  SG +Y    LD E    +Q+ V A D G PP SA  T            
Sbjct: 804 PVGTYVSINSDSGHMYALRSLDYEQIRSFQIQVQAQDAGFPPLSANVTVHIFVLDQNDNA 863

Query: 364 XXF---MP--GQYEVELA-EDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSIT 415
                 MP  G    EL      PG  V T++A DAD   ++RL Y++        FS+ 
Sbjct: 864 PVIVSPMPRNGSVATELVPRSAGPGYLVGTVSAVDADAGLNSRLSYQLLQATDFTLFSLA 923

Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYT 475
              G  L T+   L+ +   R  L V   D G  + +A V + ++       V E  P T
Sbjct: 924 PDTGE-LRTLRSFLE-QDAARQRLVVQVRDGGQPALSATVSLLLS-------VVETMPQT 974

Query: 476 ASVFED 481
            S F +
Sbjct: 975 LSDFSN 980



 Score =  162 bits (393), Expect = 1e-37
 Identities = 121/348 (34%), Positives = 163/348 (46%), Gaps = 23/348 (6%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS--SEI 512
           V++ + D N++AP F    Y   V E A +G    + SA D DVG N+  TY LS  S  
Sbjct: 420 VEVEVLDINDHAPTFPWQEYVLEVAESAVLGARFPLESAQDPDVGTNSVHTYQLSPNSFF 479

Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572
           S E     D       +   +   + LDRE    + L +TA DGG+P  S T  V ++V+
Sbjct: 480 SLEVHTRSDAS-----KFAELVLERALDREQQRTHRLLLTALDGGIPRRSGTAHVLVTVL 534

Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD----PKDREEG 628
           D NDN P F Q  Y  ++ EDA  GT V Q+ ATD D G NG I Y       P  RE  
Sbjct: 535 DANDNIPAFDQPSYGVSLPEDAPAGTLVIQLNATDLDEGPNGEIEYSFSGHAPPSVRE-- 592

Query: 629 SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688
            F ++P SG +     LD E  + H+L   A D G    +    V + + D+ND+ P   
Sbjct: 593 LFRVEPRSGQVLLKGPLDYERASLHELYVQAKDRGPSAVAVHCRVLVHLLDVNDNAPEVT 652

Query: 689 SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG-SDKAE 747
              ++  + E++P GT I  I   D D G N  V   +     S S   E R    D   
Sbjct: 653 LTSVSTPVQEDAPPGTVIAVISVLDRDSGDNGRVSCEL-----SPSVPFELRSSFRDYYT 707

Query: 748 LVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792
           LVT   LD E+   +Y + I A    SP L     + + V+DVNDNAP
Sbjct: 708 LVTTEPLDREAV-SEYNISITARDMGSPALLTRSTLTVPVSDVNDNAP 754


>UniRef50_Q9VFH5 Cluster: CG3389-PA; n=2; Sophophora|Rep: CG3389-PA
           - Drosophila melanogaster (Fruit fly)
          Length = 2002

 Score =  213 bits (521), Expect = 4e-53
 Identities = 206/745 (27%), Positives = 325/745 (43%), Gaps = 78/745 (10%)

Query: 88  DVFRID---GRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDN 144
           ++ RI+   G    +     LDRE    Y +++  TD  S  SD    T +  + + D N
Sbjct: 109 EIIRIENTGGNEAKIFLAKELDRELQDEYAIVLTLTD--SHYSDHNYVTQSFLLLVEDIN 166

Query: 145 DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY---AIIGGNTQMQFS 201
           DN P F      + + E  +     V++ ++ATDAD GA   + Y    + G N     +
Sbjct: 167 DNVPTFLPYQNAIEIPEGSAPG---VVSTLEATDADEGAYGQVVYYLQELDGDNDVFSIA 223

Query: 202 IDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS--PSRSNTTQLLINIRDVNDNAPRFYT 259
                G + L K LDYE+   Y+L + A D  +  P  + T  +L+ ++D+ D  P F  
Sbjct: 224 THQGKGILRLQKELDYERKSLYQLRVLAIDRANQGPINTGTAAILVKVKDLEDQPPEFVE 283

Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319
                 ++E+ P+G  ++RV+A D D G+N  + Y++   D          I+P +G V+
Sbjct: 284 VQAVARIAEDAPVGTKVLRVRAIDGDRGINNPIAYSLEANDL-------FDINPHTGIVH 336

Query: 320 TSGQLDRETQA-----KYQLLVTATD-GGDPPRSATATXXXXXXXXXXXXXXFMP--GQ- 370
           T  +LDRE Q+      + L ++AT+      + A  T               +P  G+ 
Sbjct: 337 TLTKLDREEQSDQVNGAHILRISATELSKSNTQMAPTTVRTEVTVIVSDVNDEIPTFGET 396

Query: 371 -YEVELAEDEPPGTPV------VTLTATDADEDNRLHYEITGGNTRGRFSITSQ------ 417
            Y  E+ E+    TP+      V     D DE N   + +        F I  +      
Sbjct: 397 VYRCEVNENAQTNTPLNFIDEEVQNVVFDHDEGNNGTFRLFLDPPNDLFEIVPELAVNEA 456

Query: 418 NGRGLITVAQPLDFKQ--ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYT 475
           N    +  ++ LDF+Q  E  + +     D   R  +A VQI I D N+  P F    Y 
Sbjct: 457 NFMLRVKNSKSLDFEQFTEVNFTIFAREVDEPSRWSSAHVQIFIRDQNDNFPEFSQTIYN 516

Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
           ASV E++   T +  V A D D G     T  +        +AH      +NP TG IT 
Sbjct: 517 ASVLENSEQDTIITHVQAVDVDSGDYG--TMGIRYTNLRGGIAH---LLNLNPITGVITI 571

Query: 536 NK----LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
            +      DRE +S + LTV A D       +T  + + ++DVNDN P F Q+ Y   ++
Sbjct: 572 KQAGGTAFDREIISRHYLTVEAIDNAGQGNRNTAQIIVDILDVNDNAPTFPQRQYETKLL 631

Query: 592 EDALVGTSVSQVGATDADVG--LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE- 648
           E+     +  Q+ A DAD+    N ++ YE+  +     +F IDP SG++R   + D E 
Sbjct: 632 ENQAEFETPLQLEARDADLNGTENSQVTYEI-VEGLYRSNFTIDPQSGLLRPVHSFDFEE 690

Query: 649 -----------------SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691
                            S+   DL   A D G P  S+ V V I ++D+ND+ P+F+   
Sbjct: 691 LVDGSSRRSDPYTGGSFSIREIDLLVRARDSGIPMLSTVVPVLIYVQDVNDNAPIFQQSF 750

Query: 692 LTFYISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750
               + E+ P G+++ ++ A D D   PN VV Y I+ G   + F + +  G        
Sbjct: 751 YAKTVPEDLPGGSSVLQVTAIDRDGSAPNNVVVYRIQTG-AGDKFIINSETGVISVAHGA 809

Query: 751 MVDLDY-ESPRKKYEL-VIRAASPP 773
            +D D  ES R  Y L V+R+   P
Sbjct: 810 NLDPDLTESKRSLYTLSVVRSKEIP 834



 Score =  212 bits (517), Expect = 1e-52
 Identities = 210/783 (26%), Positives = 354/783 (45%), Gaps = 77/783 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTADT 69
            I V D ND++P+F+   Y  +V E    G++VL + A D+D    N  V Y I+    D 
Sbjct: 734  IYVQDVNDNAPIFQQSFYAKTVPEDLPGGSSVLQVTAIDRDGSAPNNVVVYRIQTGAGDK 793

Query: 70   --LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV- 126
              +N E              D+      S   L   S+ R K   +  ++K      P  
Sbjct: 794  FIINSETGVISVAHGANLDPDLTE----SKRSLYTLSVVRSKEIPFCRILKPFRNCLPQI 849

Query: 127  -------SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA 179
                   + +L +T T++++I D N+  P   E    + + E+  V    ++ +I+ATD 
Sbjct: 850  ALDGGLGNSQLMTTCTVNISIQDVNNKPPVLKEMP-ALQILENTPV--GTLVYRIQATDL 906

Query: 180  DVGANSAIRYAI----IGGNTQM-------------QFSIDSLSGDVSLVKTLDYEQVRS 222
            D  A   +RY +      G T+               F +DS+ G + +VK LD E+V  
Sbjct: 907  DHKA--ILRYKLNPEHCEGRTEEGALVKSSEYDFLGAFEVDSIEGTLKVVKLLDRERVEH 964

Query: 223  YRLVIRAQDGGSPSRSNTTQ--LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQ 280
             +L I  +D  +       +  L I + D NDN P+F    +++S++EN   G  IV V 
Sbjct: 965  IKLAITVEDLAAAKGRQIAEGFLSIQVLDENDNNPKFRLPFYRQSITENSINGAMIVNVL 1024

Query: 281  AYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD 340
            A D D+  N  +TY +       ++   + +DP++G +  + ++D E        V ATD
Sbjct: 1025 ASDVDK--NRTITYALEGNPTYRSL---MHLDPQTGEIVVASKIDHEQHQWLNFSVRATD 1079

Query: 341  GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--R 398
             G P RS+                 F+ G     ++E+  PGT V TL A DAD  +  +
Sbjct: 1080 SGIPARSSLVDVYITVLDENDNNPYFVGGSKNYTISENAAPGTRVATLQAGDADSGDFGK 1139

Query: 399  LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS------GGRSDT 452
            + + +   +++G+F+I +    G++TVA  LD + +  Y L + A D+       G S  
Sbjct: 1140 ITFLMDRISSQGKFTIDADT--GVLTVADRLDRESKDSYNLVIEAWDNYQFGFLAGESRN 1197

Query: 453  AMVQ--INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD--VGINAQITYSL 508
            A  Q  I+I D N+  P  +       + E   +   V  +   D+D     N ++ +++
Sbjct: 1198 AFKQVFISILDENDNPPEVDLPMSCVLITEYHELHERVASIVGKDADDPTTPNGRLDFAI 1257

Query: 509  SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568
            +    N+      +Q  I+     I  +K L R     Y LT+T RD G+P+      ++
Sbjct: 1258 TR--GNKDGMFELRQ--IDAWNAQIFASKSL-RNRYGNYSLTITTRDMGLPANIVHNTLD 1312

Query: 569  ISVVDVNDNEPVFKQQLY--TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD-R 625
            I V D ND+ PVF + L+  T  I E+A VGT + Q  A+D D+G N  + Y L P    
Sbjct: 1313 ICVSDFNDHAPVFVRPLHNTTVRIPENATVGTLILQAYASDGDMGQNALVRYRLKPDPLG 1372

Query: 626  EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSP 684
                F +D ++G +   + L+RE    H+++  A D G P   SS + + I + ++ND  
Sbjct: 1373 SYKMFEVDGSTGELFLKEQLNREKQKIHEIRIEAYDQGLPTSLSSDLDLTIYVRNVNDYE 1432

Query: 685  PVFESDCLTFYISENSPIGT-------TI--GEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735
            P F  + ++   +E+S  G+       TI   ++   DP++ P+ V  Y I  G+++  F
Sbjct: 1433 PQFMVNEISVNFTEHSDPGSERIKLPDTIDKDQLELDDPNDTPSQVC-YFIVNGNEAGYF 1491

Query: 736  SLE 738
             L+
Sbjct: 1492 RLD 1494



 Score =  202 bits (493), Expect = 1e-49
 Identities = 206/739 (27%), Positives = 321/739 (43%), Gaps = 96/739 (12%)

Query: 104  SLDREKVAR--YTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE 161
            SLD E+     +T+  +  D+ S    R SS A + + I D NDN+P+FS+  Y  SV E
Sbjct: 467  SLDFEQFTEVNFTIFAREVDEPS----RWSS-AHVQIFIRDQNDNFPEFSQTIYNASVLE 521

Query: 162  DISVTDNPVIAKIKATDADVG--ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT----L 215
            +     + +I  ++A D D G      IRY  + G      +++ ++G +++ +      
Sbjct: 522  NSE--QDTIITHVQAVDVDSGDYGTMGIRYTNLRGGIAHLLNLNPITGVITIKQAGGTAF 579

Query: 216  DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275
            D E +  + L + A D       NT Q++++I DVNDNAP F    ++  + EN     +
Sbjct: 580  DREIISRHYLTVEAIDNAGQGNRNTAQIIVDILDVNDNAPTFPQRQYETKLLENQAEFET 639

Query: 276  IVRVQAYDAD-EGV-NAELTYTMTDKDYTGNVDLPITIDPRSGWVY-------------T 320
             ++++A DAD  G  N+++TY + +  Y  N     TIDP+SG +              +
Sbjct: 640  PLQLEARDADLNGTENSQVTYEIVEGLYRSN----FTIDPQSGLLRPVHSFDFEELVDGS 695

Query: 321  SGQLDRETQAKYQ-----LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375
            S + D  T   +      LLV A D G P  S                  F    Y   +
Sbjct: 696  SRRSDPYTGGSFSIREIDLLVRARDSGIPMLSTVVPVLIYVQDVNDNAPIFQQSFYAKTV 755

Query: 376  AEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL--- 429
             ED P G+ V+ +TA D D    +N + Y I  G    +F I S+ G  +I+VA      
Sbjct: 756  PEDLPGGSSVLQVTAIDRDGSAPNNVVVYRIQTG-AGDKFIINSETG--VISVAHGANLD 812

Query: 430  -DFKQERRYVLTVS-----------------------ATDSG-GRSD---TAMVQINITD 461
             D  + +R + T+S                       A D G G S    T  V I+I D
Sbjct: 813  PDLTESKRSLYTLSVVRSKEIPFCRILKPFRNCLPQIALDGGLGNSQLMTTCTVNISIQD 872

Query: 462  ANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD------VGINAQITYSLSSEISNE 515
             NN  PV +  P    + E+ P+GT V  + ATD D        +N +     + E +  
Sbjct: 873  VNNKPPVLKEMP-ALQILENTPVGTLVYRIQATDLDHKAILRYKLNPEHCEGRTEEGALV 931

Query: 516  AVAHHD--QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD--VEISV 571
              + +D    F ++   G +   KLLDRE +    L +T  D          +  + I V
Sbjct: 932  KSSEYDFLGAFEVDSIEGTLKVVKLLDRERVEHIKLAITVEDLAAAKGRQIAEGFLSIQV 991

Query: 572  VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631
            +D NDN P F+   Y  +I E+++ G  +  V A+D D   N  I Y L+          
Sbjct: 992  LDENDNNPKFRLPFYRQSITENSINGAMIVNVLASDVD--KNRTITYALEGNPTYRSLMH 1049

Query: 632  IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691
            +DP +G I     +D E     +    A D G P +SS V V+I + D ND+ P F    
Sbjct: 1050 LDPQTGEIVVASKIDHEQHQWLNFSVRATDSGIPARSSLVDVYITVLDENDNNPYFVGGS 1109

Query: 692  LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751
              + ISEN+  GT +  ++A D D G    + + +        F+++   G     ++T+
Sbjct: 1110 KNYTISENAAPGTRVATLQAGDADSGDFGKITFLMDRISSQGKFTIDADTG-----VLTV 1164

Query: 752  VD-LDYESPRKKYELVIRA 769
             D LD ES +  Y LVI A
Sbjct: 1165 ADRLDRES-KDSYNLVIEA 1182



 Score =  192 bits (469), Expect = 9e-47
 Identities = 251/934 (26%), Positives = 388/934 (41%), Gaps = 121/934 (12%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V D  D  P F   Q  A + E A  GT VL ++A D D G N  + Y++E      +
Sbjct: 269  VKVKDLEDQPPEFVEVQAVARIAEDAPVGTKVLRVRAIDGDRGINNPIAYSLEANDLFDI 328

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            NP              +   + D  +GA + R S         T L K+  Q +P + R 
Sbjct: 329  NPHTGIVHTLTKLDREE---QSDQVNGAHILRISA--------TELSKSNTQMAPTTVRT 377

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTD--NPVIAKIKAT--DADVGANSA 186
              T    V + D ND  P F E  Y   V+E+       N +  +++    D D G N  
Sbjct: 378  EVT----VIVSDVNDEIPTFGETVYRCEVNENAQTNTPLNFIDEEVQNVVFDHDEGNNGT 433

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLV------KTLDYEQVRSYRLVIRAQDGGSPSRSNT 240
             R  +   N   +   +    + + +      K+LD+EQ       I A++   PSR ++
Sbjct: 434  FRLFLDPPNDLFEIVPELAVNEANFMLRVKNSKSLDFEQFTEVNFTIFAREVDEPSRWSS 493

Query: 241  TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
              + I IRD NDN P F  +++  SV EN      I  VQA D D G    +    T  +
Sbjct: 494  AHVQIFIRDQNDNFPEFSQTIYNASVLENSEQDTIITHVQAVDVDSGDYGTMGIRYT--N 551

Query: 301  YTGNVDLPITIDPRSGWVYTSGQ-----LDRETQAKYQLLVTATDGGDPPRSATATXXXX 355
              G +   + ++P +G V T  Q      DRE  +++ L V A D        TA     
Sbjct: 552  LRGGIAHLLNLNPITG-VITIKQAGGTAFDREIISRHYLTVEAIDNAGQGNRNTAQIIVD 610

Query: 356  XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD----EDNRLHYEITGGNTRGR 411
                      F   QYE +L E++      + L A DAD    E++++ YEI  G  R  
Sbjct: 611  ILDVNDNAPTFPQRQYETKLLENQAEFETPLQLEARDADLNGTENSQVTYEIVEGLYRSN 670

Query: 412  FSITSQNGRGLITVAQPLDFKQ-----ERR---YV----------LTVSATDSG--GRSD 451
            F+I  Q+  GL+      DF++      RR   Y           L V A DSG    S 
Sbjct: 671  FTIDPQS--GLLRPVHSFDFEELVDGSSRRSDPYTGGSFSIREIDLLVRARDSGIPMLST 728

Query: 452  TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI-NAQITYSLSS 510
               V I + D N+ AP+F+ + Y  +V ED P G++VL V+A D D    N  + Y + +
Sbjct: 729  VVPVLIYVQDVNDNAPIFQQSFYAKTVPEDLPGGSSVLQVTAIDRDGSAPNNVVVYRIQT 788

Query: 511  EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT------------------ 552
               ++ +  + +  VI+   GA   +  L     S Y L+V                   
Sbjct: 789  GAGDKFII-NSETGVISVAHGA-NLDPDLTESKRSLYTLSVVRSKEIPFCRILKPFRNCL 846

Query: 553  ---ARDGGV--PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
               A DGG+    L  T  V IS+ DVN+  PV K ++    I+E+  VGT V ++ ATD
Sbjct: 847  PQIALDGGLGNSQLMTTCTVNISIQDVNNKPPVLK-EMPALQILENTPVGTLVYRIQATD 905

Query: 608  ADVGLNGRIHYELDPKDREE----------------GSFVIDPASGVIRTNKALDRESVA 651
             D      + Y+L+P+  E                 G+F +D   G ++  K LDRE V 
Sbjct: 906  LD--HKAILRYKLNPEHCEGRTEEGALVKSSEYDFLGAFEVDSIEGTLKVVKLLDRERV- 962

Query: 652  THDLKAVAID---GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
             H   A+ ++        Q +   + I++ D ND+ P F        I+ENS  G  I  
Sbjct: 963  EHIKLAITVEDLAAAKGRQIAEGFLSIQVLDENDNNPKFRLPFYRQSITENSINGAMIVN 1022

Query: 709  IRAHDPDEGPNAVVHYSIKGGDDSNS-FSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
            + A D D+  N  + Y+++G     S   L+ + G    E+V    +D+E   +     +
Sbjct: 1023 VLASDVDK--NRTITYALEGNPTYRSLMHLDPQTG----EIVVASKIDHEQ-HQWLNFSV 1075

Query: 768  RAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVT 824
            RA     P   + V V I V D NDN P        +   ++  P      + A DAD  
Sbjct: 1076 RATDSGIPARSSLVDVYITVLDENDNNPYFVGGSKNYTISENAAPGTRVATLQAGDADSG 1135

Query: 825  D--KLQYRILSGNNANLILLNETTGSMTLSPQLN 856
            D  K+ + +   ++     ++  TG +T++ +L+
Sbjct: 1136 DFGKITFLMDRISSQGKFTIDADTGVLTVADRLD 1169



 Score =  161 bits (392), Expect = 2e-37
 Identities = 160/567 (28%), Positives = 248/567 (43%), Gaps = 52/567 (9%)

Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326
           S    +G  I  ++ YD D   N  LT+   +   +  + +  T       ++ + +LDR
Sbjct: 76  SPETKVGTLIYTLKGYDPD---NDPLTFGKRNSHDSEIIRIENT-GGNEAKIFLAKELDR 131

Query: 327 ETQAKYQLLVTATDGGDPPRS-ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
           E Q +Y +++T TD      +  T +              F+P Q  +E+ E   PG  V
Sbjct: 132 ELQDEYAIVLTLTDSHYSDHNYVTQSFLLLVEDINDNVPTFLPYQNAIEIPEGSAPGV-V 190

Query: 386 VTLTATDADED---NRLHY--EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440
            TL ATDADE      ++Y  E+ G N    FSI +  G+G++ + + LD++++  Y L 
Sbjct: 191 STLEATDADEGAYGQVVYYLQELDGDNDV--FSIATHQGKGILRLQKELDYERKSLYQLR 248

Query: 441 VSATDSGGR----SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496
           V A D   +    + TA + + + D  +  P F      A + EDAP+GT VL V A D 
Sbjct: 249 VLAIDRANQGPINTGTAAILVKVKDLEDQPPEFVEVQAVARIAEDAPVGTKVLRVRAIDG 308

Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS-----GYLLTV 551
           D GIN  I YSL +          +  F INP TG + T   LDRE  S      ++L +
Sbjct: 309 DRGINNPIAYSLEA----------NDLFDINPHTGIVHTLTKLDREEQSDQVNGAHILRI 358

Query: 552 TARDGGVPS--LSDTT---DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
           +A +    +  ++ TT   +V + V DVND  P F + +Y   + E+A   T ++ +   
Sbjct: 359 SATELSKSNTQMAPTTVRTEVTVIVSDVNDEIPTFGETVYRCEVNENAQTNTPLNFIDEE 418

Query: 607 ------DADVGLNGRIHYELDP-KDREE--GSFVIDPASGVIRT--NKALDRESVATHDL 655
                 D D G NG     LDP  D  E      ++ A+ ++R   +K+LD E     + 
Sbjct: 419 VQNVVFDHDEGNNGTFRLFLDPPNDLFEIVPELAVNEANFMLRVKNSKSLDFEQFTEVNF 478

Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
              A +   P + S+  V I I D ND+ P F        + ENS   T I  ++A D D
Sbjct: 479 TIFAREVDEPSRWSSAHVQIFIRDQNDNFPEFSQTIYNASVLENSEQDTIITHVQAVDVD 538

Query: 716 EGPNAV--VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV--IRAAS 771
            G      + Y+   G  ++  +L    G    +       D E   + Y  V  I  A 
Sbjct: 539 SGDYGTMGIRYTNLRGGIAHLLNLNPITGVITIKQAGGTAFDREIISRHYLTVEAIDNAG 598

Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQ 798
               N  ++ + + DVNDNAP     Q
Sbjct: 599 QGNRNTAQIIVDILDVNDNAPTFPQRQ 625



 Score =  159 bits (387), Expect = 8e-37
 Identities = 185/678 (27%), Positives = 289/678 (42%), Gaps = 87/678 (12%)

Query: 13  VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72
           V D ND+ P F   Q    + EG++ G  V TL+ATD D G   +V Y ++ +  D    
Sbjct: 162 VEDINDNVPTFLPYQNAIEIPEGSAPG-VVSTLEATDADEGAYGQVVYYLQELDGD---- 216

Query: 73  EDAXXXXXXXXXXVQDVFRIDGR--SGALLTRASLDREKVARYTVLVKATDQAS--PVSD 128
                          DVF I      G L  +  LD E+ + Y + V A D+A+  P++ 
Sbjct: 217 --------------NDVFSIATHQGKGILRLQKELDYERKSLYQLRVLAIDRANQGPIN- 261

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             + TA I V + D  D  P+F E      + ED  V     + +++A D D G N+ I 
Sbjct: 262 --TGTAAILVKVKDLEDQPPEFVEVQAVARIAEDAPV--GTKVLRVRAIDGDRGINNPIA 317

Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY--RLVIRAQDGGSPSRSNT------ 240
           Y++   +    F I+  +G V  +  LD E+         I        S+SNT      
Sbjct: 318 YSLEANDL---FDINPHTGIVHTLTKLDREEQSDQVNGAHILRISATELSKSNTQMAPTT 374

Query: 241 --TQLLINIRDVNDNAPRFYTSLFQESVSE----NVPIGYSIVRVQ--AYDADEGVNAEL 292
             T++ + + DVND  P F  ++++  V+E    N P+ +    VQ   +D DEG N   
Sbjct: 375 VRTEVTVIVSDVNDEIPTFGETVYRCEVNENAQTNTPLNFIDEEVQNVVFDHDEGNNGTF 434

Query: 293 TYTMTDKDYTGNVDLPITIDPRSGW--VYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350
              +   +    +   + ++  +    V  S  LD E   +    + A +  +P R ++A
Sbjct: 435 RLFLDPPNDLFEIVPELAVNEANFMLRVKNSKSLDFEQFTEVNFTIFAREVDEPSRWSSA 494

Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG 410
                          F    Y   + E+    T +  + A D D  +     I   N RG
Sbjct: 495 HVQIFIRDQNDNFPEFSQTIYNASVLENSEQDTIITHVQAVDVDSGDYGTMGIRYTNLRG 554

Query: 411 RFS-ITSQNG-RGLITVAQP--LDFKQE--RRYVLTVSATDSGGRS--DTAMVQINITDA 462
             + + + N   G+IT+ Q     F +E   R+ LTV A D+ G+   +TA + ++I D 
Sbjct: 555 GIAHLLNLNPITGVITIKQAGGTAFDREIISRHYLTVEAIDNAGQGNRNTAQIIVDILDV 614

Query: 463 NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG--INAQITYSLSSEISNEAVAHH 520
           N+ AP F    Y   + E+     T L + A D+D+    N+Q+TY +   +       +
Sbjct: 615 NDNAPTFPQRQYETKLLENQAEFETPLQLEARDADLNGTENSQVTYEIVEGL-------Y 667

Query: 521 DQQFVINPQTGAITTNKLLD-RETMSG-------YL----------LTVTARDGGVPSLS 562
              F I+PQ+G +      D  E + G       Y           L V ARD G+P LS
Sbjct: 668 RSNFTIDPQSGLLRPVHSFDFEELVDGSSRRSDPYTGGSFSIREIDLLVRARDSGIPMLS 727

Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL-NGRIHYELD 621
               V I V DVNDN P+F+Q  Y   + ED   G+SV QV A D D    N  + Y + 
Sbjct: 728 TVVPVLIYVQDVNDNAPIFQQSFYAKTVPEDLPGGSSVLQVTAIDRDGSAPNNVVVYRIQ 787

Query: 622 PKDREEGSFVIDPASGVI 639
               ++  F+I+  +GVI
Sbjct: 788 TGAGDK--FIINSETGVI 803



 Score =  155 bits (375), Expect = 2e-35
 Identities = 189/718 (26%), Positives = 299/718 (41%), Gaps = 72/718 (10%)

Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ-LLINIRDVNDNAPRFYTSLFQESVS 267
           + L K LD E    Y +V+   D      +  TQ  L+ + D+NDN P F        + 
Sbjct: 123 IFLAKELDRELQDEYAIVLTLTDSHYSDHNYVTQSFLLLVEDINDNVPTFLPYQNAIEIP 182

Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
           E    G  +  ++A DADEG   ++ Y + + D   +V   I      G +    +LD E
Sbjct: 183 EGSAPGV-VSTLEATDADEGAYGQVVYYLQELDGDNDV-FSIATHQGKGILRLQKELDYE 240

Query: 328 TQAKYQLLVTATDGGD--PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
            ++ YQL V A D  +  P  + TA               F+  Q    +AED P GT V
Sbjct: 241 RKSLYQLRVLAIDRANQGPINTGTAAILVKVKDLEDQPPEFVEVQAVARIAEDAPVGTKV 300

Query: 386 VTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER-----RYV 438
           + + A D D   +N + Y +   +    F I    G  ++     LD +++       ++
Sbjct: 301 LRVRAIDGDRGINNPIAYSLEANDL---FDINPHTG--IVHTLTKLDREEQSDQVNGAHI 355

Query: 439 LTVSATDSGGRSDTAM--------VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
           L +SAT+   +S+T M        V + ++D N+  P F    Y   V E+A   T +  
Sbjct: 356 LRISATELS-KSNTQMAPTTVRTEVTVIVSDVNDEIPTFGETVYRCEVNENAQTNTPLNF 414

Query: 491 VSAT------DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA--ITTNKLLDRE 542
           +         D D G N   T+ L  +  N+ +     +  +N       +  +K LD E
Sbjct: 415 IDEEVQNVVFDHDEGNNG--TFRLFLDPPND-LFEIVPELAVNEANFMLRVKNSKSLDFE 471

Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
             +    T+ AR+   PS   +  V+I + D NDN P F Q +Y A+++E++   T ++ 
Sbjct: 472 QFTEVNFTIFAREVDEPSRWSSAHVQIFIRDQNDNFPEFSQTIYNASVLENSEQDTIITH 531

Query: 603 VGATDADVGLNGR--IHYELDPKDREEGSFVIDPASGVIRTNK----ALDRESVATHDLK 656
           V A D D G  G   I Y  + +        ++P +GVI   +    A DRE ++ H L 
Sbjct: 532 VQAVDVDSGDYGTMGIRY-TNLRGGIAHLLNLNPITGVITIKQAGGTAFDREIISRHYLT 590

Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
             AID       +T  + + I D+ND+ P F        + EN     T  ++ A D D 
Sbjct: 591 VEAIDNAGQGNRNTAQIIVDILDVNDNAPTFPQRQYETKLLENQAEFETPLQLEARDADL 650

Query: 717 G--PNAVVHYSIKGGDDSNSFSLETRQG-------SDKAELV---TMVDLDYESPR---K 761
               N+ V Y I  G   ++F+++ + G        D  ELV   +     Y       +
Sbjct: 651 NGTENSQVTYEIVEGLYRSNFTIDPQSGLLRPVHSFDFEELVDGSSRRSDPYTGGSFSIR 710

Query: 762 KYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVP 817
           + +L++RA     P L   V V I V DVNDNAP+ +          +  P G    +V 
Sbjct: 711 EIDLLVRARDSGIPMLSTVVPVLIYVQDVNDNAPIFQQ-SFYAKTVPEDLPGGSSVLQVT 769

Query: 818 AYDAD---VTDKLQYRILSGNNANLILLNET-----TGSMTLSPQLNTNVPKLATMEV 867
           A D D     + + YRI +G     I+ +ET          L P L  +   L T+ V
Sbjct: 770 AIDRDGSAPNNVVVYRIQTGAGDKFIINSETGVISVAHGANLDPDLTESKRSLYTLSV 827



 Score =  152 bits (369), Expect = 1e-34
 Identities = 175/737 (23%), Positives = 312/737 (42%), Gaps = 85/737 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I VLD ND++P F +  Y  S+ E + +G  ++ + A+D D  KN  + Y +E       
Sbjct: 989  IQVLDENDNNPKFRLPFYRQSITENSINGAMIVNVLASDVD--KNRTITYALEG------ 1040

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            NP              + +  +D ++G ++  + +D E+       V+ATD   P     
Sbjct: 1041 NP------------TYRSLMHLDPQTGEIVVASKIDHEQHQWLNFSVRATDSGIPAR--- 1085

Query: 131  SSTATIHVNIIDDNDNYPQF--SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            SS   +++ ++D+NDN P F    K YT+S +          +A ++A DAD G    I 
Sbjct: 1086 SSLVDVYITVLDENDNNPYFVGGSKNYTISEN----AAPGTRVATLQAGDADSGDFGKIT 1141

Query: 189  YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG------GSPSRSNTTQ 242
            + +   ++Q +F+ID+ +G +++   LD E   SY LVI A D          SR+   Q
Sbjct: 1142 FLMDRISSQGKFTIDADTGVLTVADRLDRESKDSYNLVIEAWDNYQFGFLAGESRNAFKQ 1201

Query: 243  LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV--NAELTYTMTDKD 300
            + I+I D NDN P     +    ++E   +   +  +   DAD+    N  L + +T  +
Sbjct: 1202 VFISILDENDNPPEVDLPMSCVLITEYHELHERVASIVGKDADDPTTPNGRLDFAITRGN 1261

Query: 301  YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
              G  +L   ID  +  ++ S  L R     Y L +T  D G P      T         
Sbjct: 1262 KDGMFELR-QIDAWNAQIFASKSL-RNRYGNYSLTITTRDMGLPANIVHNTLDICVSDFN 1319

Query: 361  XXXXXFMPGQYE--VELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITS 416
                 F+   +   V + E+   GT ++   A+D D  ++  + Y +   +  G + +  
Sbjct: 1320 DHAPVFVRPLHNTTVRIPENATVGTLILQAYASDGDMGQNALVRYRLKP-DPLGSYKMFE 1378

Query: 417  QNGR-GLITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENA 472
             +G  G + + + L+ ++++ + + + A D G     S    + I + + N+Y P F   
Sbjct: 1379 VDGSTGELFLKEQLNREKQKIHEIRIEAYDQGLPTSLSSDLDLTIYVRNVNDYEPQFMVN 1438

Query: 473  PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ-QFVINPQTG 531
              + +  E +  G+  + +  T     +         S++    V  ++   F ++P+T 
Sbjct: 1439 EISVNFTEHSDPGSERIKLPDTIDKDQLELDDPNDTPSQVCYFIVNGNEAGYFRLDPETH 1498

Query: 532  AITTNKLLDRETMSGYLLTVTARDG-GVPSLSDTTDVEISVVDVND--NEPVFKQQL-YT 587
             +T ++ LDRE ++ + L V A +     S+S         +++N+     V  QQ  Y 
Sbjct: 1499 ILTVDRELDREVIANFTLYVRATENCRNDSISGGEKRRRMGIEINNRLGGIVHNQQFGYD 1558

Query: 588  ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647
                   L  T  ++ G  DA++     + YE     +E      DP  G+  T+  LD 
Sbjct: 1559 RFKHSRQLRSTESNEYGPEDAEL-----LSYEAYDSSQE------DPTGGLATTHPELD- 1606

Query: 648  ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
                                S+ + V +++ DIND+PP F S   T  I+ N+  G    
Sbjct: 1607 --------------------STVIKVKVRVLDINDNPPRFRSKIFTGGITTNADFGLKFM 1646

Query: 708  EIRAHDPDEGPNAVVHY 724
             + A D DEG N  + Y
Sbjct: 1647 RVEATDADEGDNGRIGY 1663



 Score =  134 bits (325), Expect = 3e-29
 Identities = 142/535 (26%), Positives = 226/535 (42%), Gaps = 48/535 (8%)

Query: 373  VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRF---------------SITSQ 417
            +++ E+ P GT V  + ATD D    L Y++   +  GR                +    
Sbjct: 886  LQILENTPVGTLVYRIQATDLDHKAILRYKLNPEHCEGRTEEGALVKSSEYDFLGAFEVD 945

Query: 418  NGRGLITVAQPLDFKQERRYVLTVSATD----SGGRSDTAMVQINITDANNYAPVFENAP 473
            +  G + V + LD ++     L ++  D     G +     + I + D N+  P F    
Sbjct: 946  SIEGTLKVVKLLDRERVEHIKLAITVEDLAAAKGRQIAEGFLSIQVLDENDNNPKFRLPF 1005

Query: 474  YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
            Y  S+ E++  G   ++V+   SDV  N  ITY+L    +  ++ H D      PQTG I
Sbjct: 1006 YRQSITENSINGA--MIVNVLASDVDKNRTITYALEGNPTYRSLMHLD------PQTGEI 1057

Query: 534  TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593
                 +D E       +V A D G+P+ S   DV I+V+D NDN P F        I E+
Sbjct: 1058 VVASKIDHEQHQWLNFSVRATDSGIPARSSLVDVYITVLDENDNNPYFVGGSKNYTISEN 1117

Query: 594  ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653
            A  GT V+ + A DAD G  G+I + +D +   +G F ID  +GV+     LDRES  ++
Sbjct: 1118 AAPGTRVATLQAGDADSGDFGKITFLMD-RISSQGKFTIDADTGVLTVADRLDRESKDSY 1176

Query: 654  DLKAVAID----GGTPPQSSTVI--VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
            +L   A D    G    +S      V I I D ND+PP  +       I+E   +   + 
Sbjct: 1177 NLVIEAWDNYQFGFLAGESRNAFKQVFISILDENDNPPEVDLPMSCVLITEYHELHERVA 1236

Query: 708  EIRAHDPDE--GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765
             I   D D+   PN  + ++I  G+    F  E RQ  D             +    Y L
Sbjct: 1237 SIVGKDADDPTTPNGRLDFAITRGNKDGMF--ELRQ-IDAWNAQIFASKSLRNRYGNYSL 1293

Query: 766  VIRAASPPLWNDV---RVEILVTDVNDNAPV-MKDFQIIFNNYKDCFPVGP-FGRVPAYD 820
             I      L  ++    ++I V+D ND+APV ++          +   VG    +  A D
Sbjct: 1294 TITTRDMGLPANIVHNTLDICVSDFNDHAPVFVRPLHNTTVRIPENATVGTLILQAYASD 1353

Query: 821  ADVTDK--LQYRILSG--NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
             D+     ++YR+      +  +  ++ +TG + L  QLN    K+  + +   D
Sbjct: 1354 GDMGQNALVRYRLKPDPLGSYKMFEVDGSTGELFLKEQLNREKQKIHEIRIEAYD 1408



 Score =  122 bits (295), Expect = 1e-25
 Identities = 144/523 (27%), Positives = 216/523 (41%), Gaps = 56/523 (10%)

Query: 369 GQYEVELAEDEPPGTPVVTL--TATDADEDNR-LHYEITGGNTRGRFSITSQNGR-GLIT 424
           GQ E+ L   E P T V TL  T    D DN  L +     +      I +  G    I 
Sbjct: 65  GQSEIVLRLKESPETKVGTLIYTLKGYDPDNDPLTFGKRNSHDSEIIRIENTGGNEAKIF 124

Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ---INITDANNYAPVFENAPYTASVFED 481
           +A+ LD + +  Y + ++ TDS       + Q   + + D N+  P F   PY  ++  +
Sbjct: 125 LAKELDRELQDEYAIVLTLTDSHYSDHNYVTQSFLLLVEDINDNVPTF--LPYQNAI--E 180

Query: 482 APIGTTVLVVS---ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
            P G+   VVS   ATD+D G   Q+ Y L     +  V         +   G +   K 
Sbjct: 181 IPEGSAPGVVSTLEATDADEGAYGQVVYYLQELDGDNDVF----SIATHQGKGILRLQKE 236

Query: 539 LDRETMSGYLLTVTARDGGV--PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
           LD E  S Y L V A D     P  + T  + + V D+ D  P F +    A I EDA V
Sbjct: 237 LDYERKSLYQLRVLAIDRANQGPINTGTAAILVKVKDLEDQPPEFVEVQAVARIAEDAPV 296

Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA----- 651
           GT V +V A D D G+N  I Y L+  D     F I+P +G++ T   LDRE  +     
Sbjct: 297 GTKVLRVRAIDGDRGINNPIAYSLEANDL----FDINPHTGIVHTLTKLDREEQSDQVNG 352

Query: 652 THDLKAVAID---GGTPPQSSTVIVHIKI--EDINDSPPVFESDCLTFYISENSPIGTTI 706
            H L+  A +     T    +TV   + +   D+ND  P F        ++EN+   T +
Sbjct: 353 AHILRISATELSKSNTQMAPTTVRTEVTVIVSDVNDEIPTFGETVYRCEVNENAQTNTPL 412

Query: 707 G----EIR--AHDPDEGPNAVVHYSIKGGDDSNSF--SLETRQGSDKAELVTMVDLDYES 758
                E++    D DEG N      +   +D       L   + +    +     LD+E 
Sbjct: 413 NFIDEEVQNVVFDHDEGNNGTFRLFLDPPNDLFEIVPELAVNEANFMLRVKNSKSLDFEQ 472

Query: 759 -PRKKYELVIRAASPPL-WNDVRVEILVTDVNDNAP----VMKDFQIIFNNYKDCFPVGP 812
                + +  R    P  W+   V+I + D NDN P     + +  ++ N+ +D      
Sbjct: 473 FTEVNFTIFAREVDEPSRWSSAHVQIFIRDQNDNFPEFSQTIYNASVLENSEQDTI---- 528

Query: 813 FGRVPAYDADVTD----KLQYRILSGNNANLILLNETTGSMTL 851
              V A D D  D     ++Y  L G  A+L+ LN  TG +T+
Sbjct: 529 ITHVQAVDVDSGDYGTMGIRYTNLRGGIAHLLNLNPITGVITI 571



 Score = 52.4 bits (120), Expect = 2e-04
 Identities = 31/110 (28%), Positives = 51/110 (46%), Gaps = 7/110 (6%)

Query: 238  SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY--- 294
            S   ++ + + D+NDN PRF + +F   ++ N   G   +RV+A DADEG N  + Y   
Sbjct: 1607 STVIKVKVRVLDINDNPPRFRSKIFTGGITTNADFGLKFMRVEATDADEGDNGRIGYYQV 1666

Query: 295  ---TMTDKDYTGNV-DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD 340
                 T  +   NV   P  +D  +G V  +    +  +  +  +V A D
Sbjct: 1667 GEIRQTLSEGLENVRKAPFLLDQETGEVQLNFDPQKGMKGYFDFVVLAND 1716



 Score = 42.7 bits (96), Expect = 0.14
 Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 6/111 (5%)

Query: 450  SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509
            S    V++ + D N+  P F +  +T  +  +A  G   + V ATD+D G N +I Y   
Sbjct: 1607 STVIKVKVRVLDINDNPPRFRSKIFTGGITTNADFGLKFMRVEATDADEGDNGRIGYYQV 1666

Query: 510  SEIS---NEAVAH-HDQQFVINPQTGAITTNKLLDRETMSGYL-LTVTARD 555
             EI    +E + +     F+++ +TG +  N    ++ M GY    V A D
Sbjct: 1667 GEIRQTLSEGLENVRKAPFLLDQETGEVQLN-FDPQKGMKGYFDFVVLAND 1716



 Score = 39.1 bits (87), Expect = 1.7
 Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 6/65 (9%)

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYT--VSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            S+   + V ++D NDN P+F  K +T  ++ + D  +       +++ATDAD G N  I 
Sbjct: 1607 STVIKVKVRVLDINDNPPRFRSKIFTGGITTNADFGLK----FMRVEATDADEGDNGRIG 1662

Query: 189  YAIIG 193
            Y  +G
Sbjct: 1663 YYQVG 1667



 Score = 37.9 bits (84), Expect = 4.0
 Identities = 17/54 (31%), Positives = 27/54 (50%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEY 60
            I  ++ VLD ND+ P F  + +   +   A  G   + ++ATD D G N  + Y
Sbjct: 1610 IKVKVRVLDINDNPPRFRSKIFTGGITTNADFGLKFMRVEATDADEGDNGRIGY 1663


>UniRef50_Q9H158 Cluster: Protocadherin alpha C1 precursor; n=12;
           Amniota|Rep: Protocadherin alpha C1 precursor - Homo
           sapiens (Human)
          Length = 963

 Score =  213 bits (519), Expect = 8e-53
 Identities = 174/640 (27%), Positives = 290/640 (45%), Gaps = 38/640 (5%)

Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV-RSYRLVIRAQDGGSPSRSNTT 241
           A S+  +  +  + ++ F +D  SG++ + +  D EQ+ R+    +   D          
Sbjct: 49  AMSSRNFRFLSSHRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELH 108

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
           ++ I++ D NDN+P F     Q  + E +  G       A D DEG N  L+Y+++   +
Sbjct: 109 KIRIHVLDTNDNSPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQH 168

Query: 302 TGNVDLPITIDPRS-GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
              +D+   +D      +     LDRE +A + L++TA DGG P RS  A          
Sbjct: 169 F-RLDMGSRVDGSEYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTN 227

Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI---TGGNTRGRFSIT 415
                F    Y  ++ E  P GT +  + A D DE  +  + Y +   T    R RF + 
Sbjct: 228 DNAPVFERSVYRTKVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVH 287

Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAP 473
            ++G   + VA  L    E      + A D G  G + TA + + +TD N++AP  +   
Sbjct: 288 PKSGE--VQVAASLG-PPETLLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLT 344

Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
            +  V EDA  GT + + S  D D+  N ++   +SS    +  A  D  +       ++
Sbjct: 345 LSNPVPEDAAPGTVIALFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYY-------SL 397

Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593
             +  LDRE +S Y + +TA D G P LS    + +SV DVNDN P F Q      + E+
Sbjct: 398 LIDGPLDREQISEYQVLITASDSGSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAEN 457

Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS----FVIDPASGVIRTNKALDRES 649
              G S+ +V A D D+G NG + YEL     E  S      ++ +SG I    + D E 
Sbjct: 458 NGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQ 517

Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF------ESDCLTFYISENSPIG 703
           +     +    DGG PP+S+TV +++ + D ND+ PV               +  ++  G
Sbjct: 518 LRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTG 577

Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK-AELVTMVDLDYESPRKK 762
             + ++ A D D G NA + Y I    DS+ F +    G  + A LV    L  ++ +++
Sbjct: 578 HLVTKVVAEDADSGSNAWLSYHISRASDSSLFRISANIGELRTARLV----LPTDAVKQR 633

Query: 763 YELVIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801
             +V+R    PPL + V + +L++  N    ++ DF+ ++
Sbjct: 634 VVVVVRDHGDPPLSSSVTLGVLLS--NSVPQLLPDFEDVW 671



 Score =  204 bits (498), Expect = 3e-50
 Identities = 170/603 (28%), Positives = 264/603 (43%), Gaps = 23/603 (3%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F +D  SG L+ R   DRE++ R       T     + D L     I ++++D NDN P 
Sbjct: 66  FGVDLPSGNLVVREPADREQLCRAKAACVLTYDLV-LEDPLE-LHKIRIHVLDTNDNSPL 123

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN---TQMQFSID-SL 205
           F      + + E +  T         A D D G+N  + Y++         M   +D S 
Sbjct: 124 FPAGDVQLHIPEFL--TPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSE 181

Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265
             ++ L K LD EQ  ++ LV+ A+DGG P+RS   Q+ I + D NDNAP F  S+++  
Sbjct: 182 YPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTK 241

Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325
           V E  P G  + RVQA D DEG N E+ Y++++      +     + P+SG V  +  L 
Sbjct: 242 VPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNST-QAELRHRFHVHPKSGEVQVAASLG 300

Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
              +   +  + A D G    ++TA                        + ED  PGT +
Sbjct: 301 -PPETLLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVI 359

Query: 386 VTLTATDADEDNRLHYEITGGNTRGRFSIT-SQNGRGLITVAQPLDFKQERRYVLTVSAT 444
              +  D D D+     I G ++ G F +T S +    + +  PLD +Q   Y + ++A+
Sbjct: 360 ALFSVKDEDLDSNGRV-ICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITAS 418

Query: 445 DSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502
           DSG    S    + +++ D N+  P F        V E+   G ++  V A D D+G N 
Sbjct: 419 DSGSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNG 478

Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
            ++Y L   IS    A       +   +GAIT     D E + G+   V  RDGG+P  S
Sbjct: 479 LVSYELLDVISEGPSA--SSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRS 536

Query: 563 DTTDVEISVVDVNDNEPVF------KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616
            T  + + VVD NDN PV          +    +   A  G  V++V A DAD G N  +
Sbjct: 537 ATVTINLFVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWL 596

Query: 617 HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676
            Y +  +  +   F I    G +RT + +         +  V  D G PP SS+V + + 
Sbjct: 597 SYHIS-RASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVL 655

Query: 677 IED 679
           + +
Sbjct: 656 LSN 658



 Score =  165 bits (402), Expect = 1e-38
 Identities = 157/585 (26%), Positives = 248/585 (42%), Gaps = 53/585 (9%)

Query: 4   PFCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
           P  +H+ +I+VLD ND+SP+F     +  + E  + G       A D D G N  + Y  
Sbjct: 104 PLELHKIRIHVLDTNDNSPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSY-- 161

Query: 63  ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRS-GALLTRASLDREKVARYTVLVKATD 121
                 +L+P                  R+DG     L+   +LDRE+ A + +++ A D
Sbjct: 162 ------SLSPSQHFRLDMGS--------RVDGSEYPELVLEKALDREQRATHLLVLTARD 207

Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181
              P     S  A + + ++D NDN P F    Y   V E  +  +  V+ +++A D D 
Sbjct: 208 GGLPAR---SGDAQVTIIVVDTNDNAPVFERSVYRTKVPE--TAPNGTVLFRVQALDPDE 262

Query: 182 GANSAIRYAIIGGNTQMQ----FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237
           G+N  ++Y+ +  +TQ +    F +   SG+V +  +L   +       I A+D G    
Sbjct: 263 GSNGEVQYS-LSNSTQAELRHRFHVHPKSGEVQVAASLGPPET-LLEAYIEARDEGVFGL 320

Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297
           ++T +LL+ + DVND+AP          V E+   G  I      D D   N  +   M+
Sbjct: 321 ASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDLDSNGRVICGMS 380

Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357
                G   L  + D     +   G LDRE  ++YQ+L+TA+D G PP S   T      
Sbjct: 381 S---AGPFQLTASFDNYYS-LLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITVSVA 436

Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFS-- 413
                   F   Q E+ +AE+  PG  +  + A D D  ++  + YE+    + G  +  
Sbjct: 437 DVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPSASS 496

Query: 414 -ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDAN-NYAPVF 469
            +  ++  G IT     DF+Q R +   V   D G   RS T  + + + D N NY  + 
Sbjct: 497 LLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYPVIL 556

Query: 470 ENAPYTASV-FEDAP----IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524
              P   SV  E  P     G  V  V A D+D G NA ++Y +S        A     F
Sbjct: 557 FPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISR-------ASDSSLF 609

Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569
            I+   G + T +L+         + V  RD G P LS +  + +
Sbjct: 610 RISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGV 654



 Score =  137 bits (331), Expect = 5e-30
 Identities = 119/408 (29%), Positives = 187/408 (45%), Gaps = 21/408 (5%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           ++I++ D N+ +P+F        + E    G    + +A D D G N  ++YSLS    +
Sbjct: 110 IRIHVLDTNDNSPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSP---S 166

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
           +         V   +   +   K LDRE  + +LL +TARDGG+P+ S    V I VVD 
Sbjct: 167 QHFRLDMGSRVDGSEYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDT 226

Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE--GSFVI 632
           NDN PVF++ +Y   + E A  GT + +V A D D G NG + Y L    + E    F +
Sbjct: 227 NDNAPVFERSVYRTKVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHV 286

Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692
            P SG ++   +L        +    A D G    +ST  + +++ D+ND  P  +   L
Sbjct: 287 HPKSGEVQVAASLGPPETLL-EAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTL 345

Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752
           +  + E++  GT I      D D   N  V   I G   +  F L T    +   L+   
Sbjct: 346 SNPVPEDAAPGTVIALFSVKDEDLDSNGRV---ICGMSSAGPFQL-TASFDNYYSLLIDG 401

Query: 753 DLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809
            LD E    +Y+++I A+   SPPL     + + V DVNDN P     Q      ++  P
Sbjct: 402 PLDREQ-ISEYQVLITASDSGSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGP 460

Query: 810 VGPFGRVPAYDADV--TDKLQYRIL----SGNNA-NLILLNETTGSMT 850
               GRV A D D+     + Y +L     G +A +L+ +  ++G++T
Sbjct: 461 GASLGRVFAQDPDLGKNGLVSYELLDVISEGPSASSLLAVESSSGAIT 508



 Score =  135 bits (326), Expect = 2e-29
 Identities = 128/465 (27%), Positives = 197/465 (42%), Gaps = 37/465 (7%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V+D ND++PVFE   Y   V E A +GT +  ++A D D G N EV+Y++   T   L
Sbjct: 221 IIVVDTNDNAPVFERSVYRTKVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAEL 280

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                              F +  +SG +   ASL   +       ++A D+       L
Sbjct: 281 RHR----------------FHVHPKSGEVQVAASLGPPETL-LEAYIEARDEG---VFGL 320

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           +STA + V + D ND+ P+    T +  V ED       VIA     D D+ +N  +   
Sbjct: 321 ASTAKLLVEVTDVNDHAPELDFLTLSNPVPED--AAPGTVIALFSVKDEDLDSNGRVICG 378

Query: 191 I-IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
           +   G  Q+  S D+    + +   LD EQ+  Y+++I A D GSP  S    + +++ D
Sbjct: 379 MSSAGPFQLTASFDNYY-SLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITVSVAD 437

Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NVDLP 308
           VNDN P F     +  V+EN   G S+ RV A D D G N  ++Y + D    G +    
Sbjct: 438 VNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPSASSL 497

Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM- 367
           + ++  SG +      D E    +   V   DGG PPRSAT T               + 
Sbjct: 498 LAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYPVILF 557

Query: 368 ----PGQYEVELA-EDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGR 420
                G   VE+       G  V  + A DAD  +   L Y I+  +    F I++  G 
Sbjct: 558 PLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSLFRISANIGE 617

Query: 421 -GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANN 464
                +  P D  ++R   + V   D G    ++ V + +  +N+
Sbjct: 618 LRTARLVLPTDAVKQR---VVVVVRDHGDPPLSSSVTLGVLLSNS 659


>UniRef50_UPI0000EB26D2 Cluster: UPI0000EB26D2 related cluster; n=1;
           Canis lupus familiaris|Rep: UPI0000EB26D2 UniRef100
           entry - Canis familiaris
          Length = 599

 Score =  212 bits (518), Expect = 1e-52
 Identities = 169/524 (32%), Positives = 248/524 (47%), Gaps = 38/524 (7%)

Query: 88  DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
           D F +   +G + T   LDRE+  RY     AT         L +   + + + D ND+ 
Sbjct: 95  DDFHVHADTGIIRTARRLDRERRDRYG-FAAAT--------LLGAVVQVEIRVNDVNDHS 145

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
           P+F   +  + V E +S     V     A D D G      Y ++    Q+++     S 
Sbjct: 146 PRFPRDSLRLDVSE-LSPPGTAVRLP-GAHDPDAGLFGTQGYTLL--LFQLRYGTPGSSP 201

Query: 208 ----DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263
               D+ L++ LD E   ++ L I A DGG P R+   ++ + + D NDN P F    ++
Sbjct: 202 PEPLDLVLLRRLDREAAAAHELHIEAWDGGRPPRTGHLRVELRVLDENDNPPVFERGEYR 261

Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323
            +V E+ P G  + RV+A D D G N  + Y++  +        P  ++  SG V     
Sbjct: 262 AAVREDAPPGAEVCRVRATDRDLGRNGLVRYSLRARQ------APFAVEELSGVVRVRRP 315

Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX----XXXXXFMPGQYEVELAEDE 379
           LDRE QA +QLLV A DGG PP  AT                     +       ++E  
Sbjct: 316 LDREAQAWHQLLVEARDGGAPPEVATVRLSVAVLDVNDNPPAIHLLLLTDGGAARVSEGA 375

Query: 380 PPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL--ITVAQPLDFKQERRY 437
            PG  V  ++ +DAD D      ++     G F++ +    G+  + VA PLD +    Y
Sbjct: 376 APGDYVARVSVSDADGDPEPRDSLSLEGGEGAFALRAGGSPGVFFLCVAGPLDREARDLY 435

Query: 438 VLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495
            L + ATD+G    +A   + + + D N+  PVF    Y  SV E A  GT VL VSATD
Sbjct: 436 DLRLVATDAGSPPLSAEETLLLRVADLNDRPPVFGRERYVGSVSEAAAPGTAVLRVSATD 495

Query: 496 SD-VGIN-AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553
           +D  G + A++ Y+L       A A     F I+P++G I+T++ LDRE      L V A
Sbjct: 496 ADEAGTDHARLRYALVHLPGRCAPA-----FAIDPESGVISTSRSLDREVQEAVELRVVA 550

Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
           +D G P LS T  V I+V DVNDNEPVF++Q+Y A + E A VG
Sbjct: 551 QDLGAPPLSATCLVSITVDDVNDNEPVFRRQVYNATLAEHAPVG 594



 Score =  198 bits (483), Expect = 2e-48
 Identities = 152/473 (32%), Positives = 227/473 (47%), Gaps = 22/473 (4%)

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
           Q+ I + DVND++PRF     +  VSE  P G ++    A+D D G+     YT+    +
Sbjct: 133 QVEIRVNDVNDHSPRFPRDSLRLDVSELSPPGTAVRLPGAHDPDAGLFGTQGYTLLL--F 190

Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
                 P +  P    +    +LDRE  A ++L + A DGG PPR+              
Sbjct: 191 QLRYGTPGSSPPEPLDLVLLRRLDREAAAAHELHIEAWDGGRPPRTGHLRVELRVLDEND 250

Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419
               F  G+Y   + ED PPG  V  + ATD D   +  + Y +     +  F++   +G
Sbjct: 251 NPPVFERGEYRAAVREDAPPGAEVCRVRATDRDLGRNGLVRYSLRA--RQAPFAVEELSG 308

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYT-- 475
             ++ V +PLD + +  + L V A D G   + A V++++   D N+  P       T  
Sbjct: 309 --VVRVRRPLDREAQAWHQLLVEARDGGAPPEVATVRLSVAVLDVNDNPPAIHLLLLTDG 366

Query: 476 --ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
             A V E A  G  V  VS +D+D   + +   SLS E    A A        +P    +
Sbjct: 367 GAARVSEGAAPGDYVARVSVSDADG--DPEPRDSLSLEGGEGAFALRAGG---SPGVFFL 421

Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593
                LDRE    Y L + A D G P LS    + + V D+ND  PVF ++ Y  ++ E 
Sbjct: 422 CVAGPLDREARDLYDLRLVATDAGSPPLSAEETLLLRVADLNDRPPVFGRERYVGSVSEA 481

Query: 594 ALVGTSVSQVGATDAD-VGLN-GRIHYEL-DPKDREEGSFVIDPASGVIRTNKALDRESV 650
           A  GT+V +V ATDAD  G +  R+ Y L     R   +F IDP SGVI T+++LDRE  
Sbjct: 482 AAPGTAVLRVSATDADEAGTDHARLRYALVHLPGRCAPAFAIDPESGVISTSRSLDREVQ 541

Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703
              +L+ VA D G PP S+T +V I ++D+ND+ PVF        ++E++P+G
Sbjct: 542 EAVELRVVAQDLGAPPLSATCLVSITVDDVNDNEPVFRRQVYNATLAEHAPVG 594



 Score =  163 bits (395), Expect = 8e-38
 Identities = 151/516 (29%), Positives = 228/516 (44%), Gaps = 43/516 (8%)

Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374
           +G + T+ +LDRE + +Y        G      A                 F      ++
Sbjct: 103 TGIIRTARRLDRERRDRYGFAAATLLG------AVVQVEIRVNDVNDHSPRFPRDSLRLD 156

Query: 375 LAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432
           ++E  PPGT V    A D D        Y +     R     +S      + + + LD +
Sbjct: 157 VSELSPPGTAVRLPGAHDPDAGLFGTQGYTLLLFQLRYGTPGSSPPEPLDLVLLRRLDRE 216

Query: 433 QERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
               + L + A D G   R+    V++ + D N+  PVFE   Y A+V EDAP G  V  
Sbjct: 217 AAAAHELHIEAWDGGRPPRTGHLRVELRVLDENDNPPVFERGEYRAAVREDAPPGAEVCR 276

Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550
           V ATD D+G N  + YSL +             F +   +G +   + LDRE  + + L 
Sbjct: 277 VRATDRDLGRNGLVRYSLRAR---------QAPFAVEELSGVVRVRRPLDREAQAWHQLL 327

Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT----ANIMEDALVGTSVSQVGAT 606
           V ARDGG P    T  + ++V+DVNDN P     L T    A + E A  G  V++V  +
Sbjct: 328 VEARDGGAPPEVATVRLSVAVLDVNDNPPAIHLLLLTDGGAARVSEGAAPGDYVARVSVS 387

Query: 607 DADVGLNGRIHYELDPKDREEGSFVI----DPASGVIRTNKALDRESVATHDLKAVAIDG 662
           DAD     R    L+     EG+F +     P    +     LDRE+   +DL+ VA D 
Sbjct: 388 DADGDPEPRDSLSLEGG---EGAFALRAGGSPGVFFLCVAGPLDREARDLYDLRLVATDA 444

Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG--PNA 720
           G+PP S+   + +++ D+ND PPVF  +     +SE +  GT +  + A D DE    +A
Sbjct: 445 GSPPLSAEETLLLRVADLNDRPPVFGRERYVGSVSEAAAPGTAVLRVSATDADEAGTDHA 504

Query: 721 VVHYSI--KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLW 775
            + Y++    G  + +F+++   G     + T   LD E  ++  EL + A    +PPL 
Sbjct: 505 RLRYALVHLPGRCAPAFAIDPESG----VISTSRSLDRE-VQEAVELRVVAQDLGAPPLS 559

Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811
               V I V DVNDN PV +  Q+      +  PVG
Sbjct: 560 ATCLVSITVDDVNDNEPVFRR-QVYNATLAEHAPVG 594



 Score =  147 bits (355), Expect = 6e-33
 Identities = 120/379 (31%), Positives = 164/379 (43%), Gaps = 32/379 (8%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ VLD ND+ PVFE  +Y A+VRE A  G  V  ++ATD+D+G+N  V Y++       
Sbjct: 242 ELRVLDENDNPPVFERGEYRAAVREDAPPGAEVCRVRATDRDLGRNGLVRYSLR------ 295

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                            Q  F ++  SG +  R  LDRE  A + +LV+A D  +P    
Sbjct: 296 ---------------ARQAPFAVEELSGVVRVRRPLDREAQAWHQLLVEARDGGAPPE-- 338

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP--VIAKIKATDADVGANSAI 187
             +T  + V ++D NDN P       T      +S    P   +A++  +DAD       
Sbjct: 339 -VATVRLSVAVLDVNDNPPAIHLLLLTDGGAARVSEGAAPGDYVARVSVSDADGDPEPRD 397

Query: 188 RYAIIGGNTQMQFSIDSLSG--DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
             ++ GG            G   + +   LD E    Y L + A D GSP  S    LL+
Sbjct: 398 SLSLEGGEGAFALRAGGSPGVFFLCVAGPLDREARDLYDLRLVATDAGSPPLSAEETLLL 457

Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG--VNAELTYTMTDKDYTG 303
            + D+ND  P F    +  SVSE    G +++RV A DADE    +A L Y +      G
Sbjct: 458 RVADLNDRPPVFGRERYVGSVSEAAAPGTAVLRVSATDADEAGTDHARLRYALV--HLPG 515

Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
                  IDP SG + TS  LDRE Q   +L V A D G PP SAT              
Sbjct: 516 RCAPAFAIDPESGVISTSRSLDREVQEAVELRVVAQDLGAPPLSATCLVSITVDDVNDNE 575

Query: 364 XXFMPGQYEVELAEDEPPG 382
             F    Y   LAE  P G
Sbjct: 576 PVFRRQVYNATLAEHAPVG 594



 Score =  121 bits (291), Expect = 3e-25
 Identities = 92/277 (33%), Positives = 135/277 (48%), Gaps = 21/277 (7%)

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583
           F ++  TG I T + LDRE    Y        G V        VEI V DVND+ P F +
Sbjct: 97  FHVHADTGIIRTARRLDRERRDRYGFAAATLLGAV------VQVEIRVNDVNDHSPRFPR 150

Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL---DPKDREEGSFVIDPASGVIR 640
                ++ E +  GT+V   GA D D GL G   Y L     +    GS   +P   V+ 
Sbjct: 151 DSLRLDVSELSPPGTAVRLPGAHDPDAGLFGTQGYTLLLFQLRYGTPGSSPPEPLDLVLL 210

Query: 641 TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700
             + LDRE+ A H+L   A DGG PP++  + V +++ D ND+PPVFE       + E++
Sbjct: 211 --RRLDREAAAAHELHIEAWDGGRPPRTGHLRVELRVLDENDNPPVFERGEYRAAVREDA 268

Query: 701 PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760
           P G  +  +RA D D G N +V YS++       F++E   G  +        LD E+ +
Sbjct: 269 PPGAEVCRVRATDRDLGRNGLVRYSLRA--RQAPFAVEELSGVVRVRR----PLDREA-Q 321

Query: 761 KKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVM 794
             ++L++ A    +PP    VR+ + V DVNDN P +
Sbjct: 322 AWHQLLVEARDGGAPPEVATVRLSVAVLDVNDNPPAI 358



 Score = 96.3 bits (229), Expect = 1e-17
 Identities = 83/280 (29%), Positives = 127/280 (45%), Gaps = 30/280 (10%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYE----ASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
           +   + VLD ND+ P   +        A V EGA+ G  V  +  +D D     + E   
Sbjct: 342 VRLSVAVLDVNDNPPAIHLLLLTDGGAARVSEGAAPGDYVARVSVSDAD----GDPE--- 394

Query: 63  ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122
                D+L+ E               VF        L     LDRE    Y + + ATD 
Sbjct: 395 ---PRDSLSLEGGEGAFALRAGGSPGVF-------FLCVAGPLDREARDLYDLRLVATDA 444

Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-V 181
            SP    LS+  T+ + + D ND  P F  + Y  SV E  +      + ++ ATDAD  
Sbjct: 445 GSPP---LSAEETLLLRVADLNDRPPVFGRERYVGSVSE--AAAPGTAVLRVSATDADEA 499

Query: 182 GANSA-IRYAIIG--GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238
           G + A +RYA++   G     F+ID  SG +S  ++LD E   +  L + AQD G+P  S
Sbjct: 500 GTDHARLRYALVHLPGRCAPAFAIDPESGVISTSRSLDREVQEAVELRVVAQDLGAPPLS 559

Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR 278
            T  + I + DVNDN P F   ++  +++E+ P+G+  ++
Sbjct: 560 ATCLVSITVDDVNDNEPVFRRQVYNATLAEHAPVGHCFLQ 599


>UniRef50_Q5CCS8 Cluster: Fc1-cadherin; n=2; Hexapoda|Rep:
           Fc1-cadherin - Folsomia candida
          Length = 1565

 Score =  212 bits (517), Expect = 1e-52
 Identities = 195/722 (27%), Positives = 320/722 (44%), Gaps = 64/722 (8%)

Query: 17  NDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAX 76
           ++++P  +  +Y+ S+ +  + G  V+ + ATD D G N  V Y  E       NP D  
Sbjct: 231 HEYNPHLDKYEYKESMPQDLALGQVVMRISATDIDDGNNGTVVYACE---PHPQNPNDV- 286

Query: 77  XXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATI 136
                      + F I   SG +  +  +  ++  ++ + + A+D   P +  ++  + +
Sbjct: 287 -----------EFFDISSASGEITLKKRIGNQQ--KFQLRIVASDLGVPPNSAITDLSIV 333

Query: 137 HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNT 196
              + + +   P+F      + +DE I     PV      ++AD   +  + + ++ G T
Sbjct: 334 ---VAEPSQRPPEFINPPTLIHLDEYIYNLSVPVATLSARSNAD---DELVFFELVNGQT 387

Query: 197 QMQ-----FSIDSL---SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
           Q       F++++    +  + L + LDYE    Y L IRAQ+    + +  T L + + 
Sbjct: 388 QPTNKEAIFTLETEGRNTAHIKLDRQLDYESTTRYTLTIRAQN--KYNLAAETLLTVMVN 445

Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYTGNVDL 307
           D ND  P ++T +   +V EN PIG S++RV+A D D    N E+TY +   D   N   
Sbjct: 446 DKNDEKP-YFTEVTTGTVLENEPIGTSVMRVRAIDTDGTAPNNEVTYHLKS-DEEDN--- 500

Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-------PRSATATXXXXXXXXX 360
             +ID  SG + T    DRE +  YQ++V A DG          P     T         
Sbjct: 501 -FSIDAISGEIKTRKMFDREEKDTYQVIVYAKDGAPSVKLNNGQPNERPQTLKIVIADKN 559

Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420
                F+   YE E++ED      VV + A DAD  + L Y IT GN    F+I S +  
Sbjct: 560 DNGPVFVRDLYEAEMSEDADLNRVVVEVRAKDADTASVLQYTITEGNIDDAFAIRSTSTS 619

Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
           G+ITV   LDF+  R+Y LTV  +DS   + T  V+I I + N+  P FE      ++ E
Sbjct: 620 GVITVKNKLDFESIRQYELTVRVSDSVHEAKT-KVKIYIQNVNDEPPKFEPMNSNTTIVE 678

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           +      +  V A D D+G +  +  ++S  I         + F + P  G +   K LD
Sbjct: 679 EFIPSDCIFRVKAYDPDIG-DRTVPQNISYFILT-----GKEHFSVGPDDGCVKVIKPLD 732

Query: 541 RETMSGYLLTVTARD--GGVPSLSD-TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
           RE    Y + V A D  G  P+  D   ++ ++++D+NDN PV   Q     +  +    
Sbjct: 733 REDKPFYQMVVGASDEWGLAPTKLDFYKELIVNLIDINDNAPVLSSQ--NPVVWNENQPR 790

Query: 598 TSVSQVGATDADVGLNG-RIHYELDPKDREEGSFVIDPASGVIRTNK-ALDRESVATHDL 655
             ++Q+ ATDAD   NG    + +DPK   +   +       ++ NK   DRE V  + +
Sbjct: 791 GPITQLDATDADSPENGPPFTFSIDPKADMKIKELFSIEGKTLKANKDDFDREEVKQYVV 850

Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSP-PVFESDCLTFYISENSPIGTTIGEIRAHDP 714
                D G   ++ T  + + I D ND+     ES    +   E +P    IG +   DP
Sbjct: 851 PIAISDSGRERKTGTSYLTVIIGDQNDNDMQDGESRIFVYKYKERNPF--PIGRVYVKDP 908

Query: 715 DE 716
           D+
Sbjct: 909 DD 910



 Score =  210 bits (513), Expect = 4e-52
 Identities = 331/1370 (24%), Positives = 547/1370 (39%), Gaps = 180/1370 (13%)

Query: 17   NDHSPVF-EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDA 75
            N H P F +   Y  S+ EG    T V+ +KA DQD  ++     T  +V+ + +  +  
Sbjct: 99   NLHKPDFVDCGSYRPSIPEGEPVDTPVIQVKALDQDPPESGGT-VTYSIVSGNEMLAD-- 155

Query: 76   XXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYT---VLVKATDQASPVSDRLSS 132
                          F +D  +G + TR   DR++ A+     V V+A+D  +P   RL +
Sbjct: 156  --------------FAVDEHTGWISTRKIFDRDEPAKEKEVYVTVQASDNGNP---RLDA 198

Query: 133  TATIHVNIIDDNDNYPQF---------------------SEKTYTVSVDEDISVTDNPVI 171
              T+ V I D NDN  QF                      +  Y  S+ +D+++    V+
Sbjct: 199  VCTLKVKITDINDNTAQFLLSRRFNQGSYVPEHEYNPHLDKYEYKESMPQDLAL--GQVV 256

Query: 172  AKIKATDADVGANSAIRYAII----GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVI 227
             +I ATD D G N  + YA        N    F I S SG+++L K +  +Q   ++L I
Sbjct: 257  MRISATDIDDGNNGTVVYACEPHPQNPNDVEFFDISSASGEITLKKRIGNQQ--KFQLRI 314

Query: 228  RAQDGGSPSRSNTTQLLINIRDVNDNAPRFY---TSLFQESVSENVPIGYSIVRVQAYDA 284
             A D G P  S  T L I + + +   P F    T +  +    N+ +  + +  ++   
Sbjct: 315  VASDLGVPPNSAITDLSIVVAEPSQRPPEFINPPTLIHLDEYIYNLSVPVATLSARSNAD 374

Query: 285  DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP 344
            DE V  EL    T       +    T    +  +    QLD E+  +Y L + A +  + 
Sbjct: 375  DELVFFELVNGQTQPTNKEAIFTLETEGRNTAHIKLDRQLDYESTTRYTLTIRAQNKYN- 433

Query: 345  PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHY 401
               A  T              +        + E+EP GT V+ + A D D    +N + Y
Sbjct: 434  --LAAETLLTVMVNDKNDEKPYFTEVTTGTVLENEPIGTSVMRVRAIDTDGTAPNNEVTY 491

Query: 402  EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD-------SGGRSDTA- 453
             +   +    FSI + +G   I   +  D +++  Y + V A D       + G+ +   
Sbjct: 492  HLKS-DEEDNFSIDAISGE--IKTRKMFDREEKDTYQVIVYAKDGAPSVKLNNGQPNERP 548

Query: 454  -MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512
              ++I I D N+  PVF    Y A + EDA +   V+ V A D+D    + + Y+++   
Sbjct: 549  QTLKIVIADKNDNGPVFVRDLYEAEMSEDADLNRVVVEVRAKDADTA--SVLQYTITEGN 606

Query: 513  SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572
             ++A A           +G IT    LD E++  Y LTV   D    +    T V+I + 
Sbjct: 607  IDDAFAIRSTS-----TSGVITVKNKLDFESIRQYELTVRVSDSVHEA---KTKVKIYIQ 658

Query: 573  DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG---LNGRIHYELDPKDREEGS 629
            +VND  P F+       I+E+ +    + +V A D D+G   +   I Y +    +E   
Sbjct: 659  NVNDEPPKFEPMNSNTTIVEEFIPSDCIFRVKAYDPDIGDRTVPQNISYFI-LTGKEH-- 715

Query: 630  FVIDPASGVIRTNKALDRESVATHDLKAVAIDG-GTPPQSSTVIVHIKIE--DINDSPPV 686
            F + P  G ++  K LDRE    + +   A D  G  P        + +   DIND+ PV
Sbjct: 716  FSVGPDDGCVKVIKPLDREDKPFYQMVVGASDEWGLAPTKLDFYKELIVNLIDINDNAPV 775

Query: 687  FESDCLTFYISENSPIG--TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD 744
              S     + +EN P G  T +    A  P+ GP     +SI    D     L + +G  
Sbjct: 776  LSSQNPVVW-NENQPRGPITQLDATDADSPENGPPFT--FSIDPKADMKIKELFSIEG-- 830

Query: 745  KAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE---ILVTDVNDNAPVMKDFQIIF 801
            K       D D E   K+Y + I  +              +++ D NDN     + +I  
Sbjct: 831  KTLKANKDDFDREEV-KQYVVPIAISDSGRERKTGTSYLTVIIGDQNDNDMQDGESRIFV 889

Query: 802  NNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPK 861
              YK+  P  P GRV   D D  D          + +   ++  TG + +      +   
Sbjct: 890  YKYKERNPF-PIGRVYVKDPDDWDLPDKTFTLTTSNSHFTVDSDTGYINMKSTAEPS-DH 947

Query: 862  LATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSP--LLGFFIDG 919
            + T +V  +   + + A + ++V+ IT+E + NS ++R    T EQF+      G     
Sbjct: 948  VLTFKVEDSRWGSTVNAKVTVTVKEITDEAVDNSGSIRFMGTTKEQFIKVDRTTGLSKKD 1007

Query: 920  -----LAAIIPCPKENIYIFSVQDDTDVTG-NILNVSFSARRPDAEVGVAGDPSPHYSPT 973
                 LA I   P EN+ +F+V +   ++  N  +V +S              SP++   
Sbjct: 1008 KLQRELARIFEVPIENVDVFTVGNSPSISDMNFFDVRYSVHN-----------SPYWKAE 1056

Query: 974  HLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLF 1033
             L  ++   +  L +   + ++    + C+ E       C   L   +    + ++   F
Sbjct: 1057 KLNGKLAESKDLLEKHLELNIVMIGIDECLKEKHFCESSCSNTLAKSDIPLKIFTNETSF 1116

Query: 1034 RPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCS 1093
              ++ +    C C       NC        C  +G   IC SG        GG+    C 
Sbjct: 1117 VGVHAIVQPVCNCSSFQPPNNC----LPNPCLNNG---ICTSG--------GGLDGFKCE 1161

Query: 1094 IDAAYTTAVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERH- 1152
             DA +    CE+ + +     F  FP L   +   L+++F   + SGL+ YNG   +   
Sbjct: 1162 CDAPFDGPRCEITSIALDGVGFAWFPSLTVCNDSSLQVEFMA-SKSGLIFYNGPIYQSSV 1220

Query: 1153 -DFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMI 1211
             DF++LEL      R G P L   +  G  + EI     + DG  H V I +    I+M 
Sbjct: 1221 TDFMSLEL------RDGKPMLLMDYGTGVSRLEIEHSPMLADGLSHKVHITWNPSAISMR 1274

Query: 1212 LDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIP 1271
            +D+C K            +  C    R         PT T +  L++ GP Q+GG+   P
Sbjct: 1275 VDECRK-----------NEPTCYRTAR---------PTGT-NSQLNVNGPFQLGGISFDP 1313

Query: 1272 SSF-------QVKNKDFV-GCISDFYIDHKFIDLN--SYVADNGTLAGCP 1311
                      Q+ +K+F  GCI++   + ++++L   SY   N T    P
Sbjct: 1314 KRLQNSMKWSQIPSKEFFQGCIANLTFNGEYVNLGNPSYSTLNVTTCDSP 1363


>UniRef50_UPI0000F1EDA6 Cluster: PREDICTED: hypothetical protein;
           n=2; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 970

 Score =  211 bits (516), Expect = 2e-52
 Identities = 167/605 (27%), Positives = 270/605 (44%), Gaps = 36/605 (5%)

Query: 97  GALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT 156
           G L     +DRE++ +       T   + VS        + V ++D NDN P+F     T
Sbjct: 82  GRLTAEERVDRERICKRNPRCVITFDVAFVSAEQFELFHVEVEVLDVNDNSPEFPRAECT 141

Query: 157 VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS-------GDV 209
           V + E  ++     IA   A D+DVG+NS   Y +   +    FSID ++        ++
Sbjct: 142 VEISESAALGTR--IALDAAEDSDVGSNSIQSYEL---SENSHFSIDVITRVDGVKYAEL 196

Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269
            LVK LD E    + L + A DGG P RS +T + + ++D NDN+P F  S +   V E+
Sbjct: 197 VLVKELDREARAFFALKLVAADGGHPPRSGSTNVTVKVKDANDNSPLFDHSHYSVDVPED 256

Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329
            P+   ++ + A D DEG+N ++ Y    K  T  +     +D ++G++     +D E +
Sbjct: 257 TPVEALLLDLNAIDPDEGLNGQVVYEF-GKQVTTEIRQLFKLDYKTGYLTLQSPVDYEDE 315

Query: 330 AKYQLLVTATD-GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV-----ELAEDEPPGT 383
             Y++ V ATD G +P  S                   +     V      ++E   P  
Sbjct: 316 TTYEIDVQATDLGHNPVPSVCKIIINIRDVNDNPPEIIITSITSVTDGVAHVSEATGPDI 375

Query: 384 PVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441
            V  ++  D D   + ++   + GG+   R     +    ++T+A PLD ++   Y LTV
Sbjct: 376 LVALISIKDKDTGANGQVSCTLNGGHGNFRLKRAYEGSYTIVTMA-PLDREKIAEYNLTV 434

Query: 442 SATDSGGRSDTAMVQ--INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499
            A D G      + Q  + +TD N+ AP F    Y   + E+   GT +  + A+D D G
Sbjct: 435 VAEDFGVPPLRTVTQYIVRLTDVNDNAPAFSAKIYEGFIEENQLPGTYITTILASDQDSG 494

Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
           +N +ITY L    +N        +F I  Q G +   +  + E      L V A D G P
Sbjct: 495 LNGEITYELFDSDTNSV-----SRFAIMNQAGNVYALQSFNYEVTKRLDLRVQASDRGWP 549

Query: 560 SLSDTTDVEISVVDVNDNEP-VFKQQLYTAN----IMEDALVGTSVSQVGATDADVGLNG 614
            L +   + I+VVD NDN P +    L   +    +  DA  G  V+++ A D+D GLN 
Sbjct: 550 QLHNNAILIINVVDQNDNTPFITHPPLINGSAEIQLPRDAPPGYIVTRIIAKDSDAGLNA 609

Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674
            + Y++   D  +  F IDP +G I  N+ +  +      +     D G P Q+ST  +H
Sbjct: 610 ELTYKI--YDGGDFGFAIDPNTGEIYINRKITYDEYDLWKVLVTVNDNGQPSQTSTATIH 667

Query: 675 IKIED 679
             + +
Sbjct: 668 FTLTE 672



 Score =  198 bits (484), Expect = 1e-48
 Identities = 163/587 (27%), Positives = 255/587 (43%), Gaps = 55/587 (9%)

Query: 8   HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
           H ++ VLD ND+SP F   +    + E A+ GT +    A D D+G N+   Y +     
Sbjct: 120 HVEVEVLDVNDNSPEFPRAECTVEISESAALGTRIALDAAEDSDVGSNSIQSYELS---- 175

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASPV 126
                             +  + R+DG +   L+    LDRE  A + + + A D   P 
Sbjct: 176 ------------ENSHFSIDVITRVDGVKYAELVLVKELDREARAFFALKLVAADGGHPP 223

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
               S +  + V + D NDN P F    Y+V V ED  V    ++  + A D D G N  
Sbjct: 224 R---SGSTNVTVKVKDANDNSPLFDHSHYSVDVPEDTPV--EALLLDLNAIDPDEGLNGQ 278

Query: 187 IRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
           + Y     +    +  F +D  +G ++L   +DYE   +Y + ++A D G     +  ++
Sbjct: 279 VVYEFGKQVTTEIRQLFKLDYKTGYLTLQSPVDYEDETTYEIDVQATDLGHNPVPSVCKI 338

Query: 244 LINIRDVNDNAPRFY-TSLFQES-----VSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297
           +INIRDVNDN P    TS+   +     VSE       +  +   D D G N +++ T+ 
Sbjct: 339 IINIRDVNDNPPEIIITSITSVTDGVAHVSEATGPDILVALISIKDKDTGANGQVSCTLN 398

Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357
                GN  L    +  S  + T   LDRE  A+Y L V A D G PP            
Sbjct: 399 GGH--GNFRLKRAYEG-SYTIVTMAPLDREKIAEYNLTVVAEDFGVPPLRTVTQYIVRLT 455

Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRG--RFS 413
                   F    YE  + E++ PGT + T+ A+D D   +  + YE+   +T    RF+
Sbjct: 456 DVNDNAPAFSAKIYEGFIEENQLPGTYITTILASDQDSGLNGEITYELFDSDTNSVSRFA 515

Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFEN 471
           I +Q G   +   Q  +++  +R  L V A+D G     + A++ IN+ D N+  P   +
Sbjct: 516 IMNQAGN--VYALQSFNYEVTKRLDLRVQASDRGWPQLHNNAILIINVVDQNDNTPFITH 573

Query: 472 APYTASVFE-----DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
            P      E     DAP G  V  + A DSD G+NA++TY +            D  F I
Sbjct: 574 PPLINGSAEIQLPRDAPPGYIVTRIIAKDSDAGLNAELTYKIYDG--------GDFGFAI 625

Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
           +P TG I  N+ +  +    + + VT  D G PS + T  +  ++ +
Sbjct: 626 DPNTGEIYINRKITYDEYDLWKVLVTVNDNGQPSQTSTATIHFTLTE 672



 Score =  198 bits (483), Expect = 2e-48
 Identities = 164/577 (28%), Positives = 255/577 (44%), Gaps = 29/577 (5%)

Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDGG-SPSRSNTTQL 243
           IR+ ++  +T          G ++  + +D E++  R+ R VI       S  +     +
Sbjct: 62  IRFKLMSPSTGSFIRFRESDGRLTAEERVDRERICKRNPRCVITFDVAFVSAEQFELFHV 121

Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
            + + DVNDN+P F  +     +SE+  +G  I    A D+D G N+  +Y +++  +  
Sbjct: 122 EVEVLDVNDNSPEFPRAECTVEISESAALGTRIALDAAEDSDVGSNSIQSYELSENSHF- 180

Query: 304 NVDLPITIDP-RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
           ++D+   +D  +   +    +LDRE +A + L + A DGG PPRS +             
Sbjct: 181 SIDVITRVDGVKYAELVLVKELDREARAFFALKLVAADGGHPPRSGSTNVTVKVKDANDN 240

Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGG-NTRGRFSITSQNG 419
              F    Y V++ ED P    ++ L A D DE  + ++ YE      T  R        
Sbjct: 241 SPLFDHSHYSVDVPEDTPVEALLLDLNAIDPDEGLNGQVVYEFGKQVTTEIRQLFKLDYK 300

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYT-- 475
            G +T+  P+D++ E  Y + V ATD G         + INI D N+  P       T  
Sbjct: 301 TGYLTLQSPVDYEDETTYEIDVQATDLGHNPVPSVCKIIINIRDVNDNPPEIIITSITSV 360

Query: 476 ----ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
               A V E       V ++S  D D G N Q++ +L+    N  +    +       + 
Sbjct: 361 TDGVAHVSEATGPDILVALISIKDKDTGANGQVSCTLNGGHGNFRLKRAYEG------SY 414

Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
            I T   LDRE ++ Y LTV A D GVP L   T   + + DVNDN P F  ++Y   I 
Sbjct: 415 TIVTMAPLDREKIAEYNLTVVAEDFGVPPLRTVTQYIVRLTDVNDNAPAFSAKIYEGFIE 474

Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKALDRESV 650
           E+ L GT ++ + A+D D GLNG I YEL   D    S F I   +G +   ++ + E  
Sbjct: 475 ENQLPGTYITTILASDQDSGLNGEITYELFDSDTNSVSRFAIMNQAGNVYALQSFNYEVT 534

Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL-----TFYISENSPIGTT 705
              DL+  A D G P   +  I+ I + D ND+ P      L        +  ++P G  
Sbjct: 535 KRLDLRVQASDRGWPQLHNNAILIINVVDQNDNTPFITHPPLINGSAEIQLPRDAPPGYI 594

Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
           +  I A D D G NA + Y I  G D   F+++   G
Sbjct: 595 VTRIIAKDSDAGLNAELTYKIYDGGDF-GFAIDPNTG 630



 Score =  157 bits (380), Expect = 5e-36
 Identities = 117/375 (31%), Positives = 177/375 (47%), Gaps = 23/375 (6%)

Query: 432 KQERRYVLTVS-ATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
           K+  R V+T   A  S  + +   V++ + D N+ +P F  A  T  + E A +GT + +
Sbjct: 97  KRNPRCVITFDVAFVSAEQFELFHVEVEVLDVNDNSPEFPRAECTVEISESAALGTRIAL 156

Query: 491 VSATDSDVGINAQITYSLS--SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
            +A DSDVG N+  +Y LS  S  S + +   D       +   +   K LDRE  + + 
Sbjct: 157 DAAEDSDVGSNSIQSYELSENSHFSIDVITRVD-----GVKYAELVLVKELDREARAFFA 211

Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
           L + A DGG P  S +T+V + V D NDN P+F    Y+ ++ ED  V   +  + A D 
Sbjct: 212 LKLVAADGGHPPRSGSTNVTVKVKDANDNSPLFDHSHYSVDVPEDTPVEALLLDLNAIDP 271

Query: 609 DVGLNGRIHYELDPKDREE--GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666
           D GLNG++ YE   +   E    F +D  +G +     +D E   T+++   A D G  P
Sbjct: 272 DEGLNGQVVYEFGKQVTTEIRQLFKLDYKTGYLTLQSPVDYEDETTYEIDVQATDLGHNP 331

Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTF------YISENSPIGTTIGEIRAHDPDEGPNA 720
             S   + I I D+ND+PP      +T       ++SE +     +  I   D D G N 
Sbjct: 332 VPSVCKIIINIRDVNDNPPEIIITSITSVTDGVAHVSEATGPDILVALISIKDKDTGANG 391

Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWND 777
            V  ++ GG    +F L+ R       +VTM  LD E   + Y L + A     PPL   
Sbjct: 392 QVSCTLNGGH--GNFRLK-RAYEGSYTIVTMAPLDREKIAE-YNLTVVAEDFGVPPLRTV 447

Query: 778 VRVEILVTDVNDNAP 792
            +  + +TDVNDNAP
Sbjct: 448 TQYIVRLTDVNDNAP 462



 Score =  137 bits (332), Expect = 4e-30
 Identities = 98/302 (32%), Positives = 145/302 (48%), Gaps = 22/302 (7%)

Query: 96  SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155
           S  ++T A LDREK+A Y + V A D   P    L +     V + D NDN P FS K Y
Sbjct: 413 SYTIVTMAPLDREKIAEYNLTVVAEDFGVPP---LRTVTQYIVRLTDVNDNAPAFSAKIY 469

Query: 156 TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQM--QFSIDSLSGDVSLVK 213
              ++E+        I  I A+D D G N  I Y +   +T    +F+I + +G+V  ++
Sbjct: 470 EGFIEEN--QLPGTYITTILASDQDSGLNGEITYELFDSDTNSVSRFAIMNQAGNVYALQ 527

Query: 214 TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF-YTSLFQESVS----E 268
           + +YE  +   L ++A D G P   N   L+IN+ D NDN P   +  L   S       
Sbjct: 528 SFNYEVTKRLDLRVQASDRGWPQLHNNAILIINVVDQNDNTPFITHPPLINGSAEIQLPR 587

Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328
           + P GY + R+ A D+D G+NAELTY    K Y G  D    IDP +G +Y + ++  + 
Sbjct: 588 DAPPGYIVTRIIAKDSDAGLNAELTY----KIYDGG-DFGFAIDPNTGEIYINRKITYDE 642

Query: 329 QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388
              +++LVT  D G P +++TAT                 G +  E  EDEP    +V +
Sbjct: 643 YDLWKVLVTVNDNGQPSQTSTATIHFTLTESAPSN-----GNFYDEREEDEPKQWTLVLI 697

Query: 389 TA 390
            A
Sbjct: 698 LA 699



 Score = 69.3 bits (162), Expect = 1e-09
 Identities = 75/291 (25%), Positives = 134/291 (46%), Gaps = 25/291 (8%)

Query: 628 GSFV-IDPASGVIRTNKALDRESVATHDLKAV-AIDGGTPPQSSTVIVHIKIE--DINDS 683
           GSF+    + G +   + +DRE +   + + V   D          + H+++E  D+ND+
Sbjct: 72  GSFIRFRESDGRLTAEERVDRERICKRNPRCVITFDVAFVSAEQFELFHVEVEVLDVNDN 131

Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE--TR- 740
            P F     T  ISE++ +GT I    A D D G N++  Y +    +++ FS++  TR 
Sbjct: 132 SPEFPRAECTVEISESAALGTRIALDAAEDSDVGSNSIQSYEL---SENSHFSIDVITRV 188

Query: 741 QGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDF 797
            G   AELV + +LD E+ R  + L + AA    PP      V + V D NDN+P+    
Sbjct: 189 DGVKYAELVLVKELDREA-RAFFALKLVAADGGHPPRSGSTNVTVKVKDANDNSPLFDHS 247

Query: 798 QIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRI---LSGNNANLILLNETTGSMTLS 852
               +  +D         + A D D  +  ++ Y     ++     L  L+  TG +TL 
Sbjct: 248 HYSVDVPEDTPVEALLLDLNAIDPDEGLNGQVVYEFGKQVTTEIRQLFKLDYKTGYLTLQ 307

Query: 853 PQLNTNVPKLATMEVSVTD-GVNEIKAMMQ--LSVRLITE---EMLLNSIT 897
             ++        ++V  TD G N + ++ +  +++R + +   E+++ SIT
Sbjct: 308 SPVDYEDETTYEIDVQATDLGHNPVPSVCKIIINIRDVNDNPPEIIITSIT 358


>UniRef50_UPI0000E20B47 Cluster: PREDICTED: similar to Protocadherin
           gamma B4 precursor (PCDH-gamma-B4) isoform 20; n=2;
           Catarrhini|Rep: PREDICTED: similar to Protocadherin
           gamma B4 precursor (PCDH-gamma-B4) isoform 20 - Pan
           troglodytes
          Length = 749

 Score =  210 bits (514), Expect = 3e-52
 Identities = 127/424 (29%), Positives = 213/424 (50%), Gaps = 16/424 (3%)

Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ-DGGSPSRSNTTQLLINIRDVNDNAPRFY 258
           F++ + SG++ +   LD E++   +     + +  + +  N   + + I D+ND+ P+F 
Sbjct: 75  FTVSAESGELLVSSRLDREEICGKKPACALEFEAVAENPLNFYHVNVEIEDINDHTPKFT 134

Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV 318
            + F+  +SE+   G   +   A+DAD G N    Y ++  D+   ++   +   +   +
Sbjct: 135 QNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHFSLINKEKSDGSKYPEM 194

Query: 319 YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAED 378
                LDRE Q  Y L +TA D G PP S+TA               F    Y V L+E+
Sbjct: 195 VLKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDIYRVSLSEN 254

Query: 379 EPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436
             PGT V+ +TATD DE  +  + +  +  +   +F + S  G   ITV   LDF++ + 
Sbjct: 255 VYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQFDLNSNTGE--ITVLNTLDFEEVKE 312

Query: 437 YVLTVSATDSGGRSDTAMVQINITDANNYAP--VFENAPYTASVFEDAPIGTTVLVVSAT 494
           Y + + A D GG      V++ + D N+ AP  +F++ P    + EDA +GT + ++   
Sbjct: 313 YSIVLEARDGGGMIAQCTVEVEVIDENDNAPEVIFQSLPNL--IMEDAELGTHIALLKVR 370

Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554
           D D   N ++T  L  ++  + +         +  T  + T+ +LDRE    Y +TVTAR
Sbjct: 371 DKDSRHNGEVTCKLEGDVPFKILTS-------SRNTYKLVTDAVLDREQNPEYNITVTAR 423

Query: 555 DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614
           D G P LS ++ + + + DVNDN PVF Q  Y  ++ E+   G S+SQV A+D D+G NG
Sbjct: 424 DRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVSASDPDLGPNG 483

Query: 615 RIHY 618
           ++ Y
Sbjct: 484 QVSY 487



 Score =  196 bits (479), Expect = 5e-48
 Identities = 127/367 (34%), Positives = 191/367 (52%), Gaps = 16/367 (4%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDAD-EDNRL-HYEITGGNTRGRFSITSQNGRGL- 422
           F    +E++++E   PGT  +  +A DAD   N L +Y+++  +     +    +G    
Sbjct: 133 FTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHFSLINKEKSDGSKYP 192

Query: 423 -ITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVF 479
            + +  PLD ++++ Y LT++A D G    S TA + + +TDAN+ APVF    Y  S+ 
Sbjct: 193 EMVLKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDIYRVSLS 252

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           E+   GTTVL V+ATD D G+NA+IT+S S        A    QF +N  TG IT    L
Sbjct: 253 ENVYPGTTVLQVTATDQDEGVNAEITFSFSE-------ASQITQFDLNSNTGEITVLNTL 305

Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
           D E +  Y + + ARDGG   +     VE+ V+D NDN P    Q     IMEDA +GT 
Sbjct: 306 DFEEVKEYSIVLEARDGG--GMIAQCTVEVEVIDENDNAPEVIFQSLPNLIMEDAELGTH 363

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
           ++ +   D D   NG +  +L+  D           +  + T+  LDRE    +++   A
Sbjct: 364 IALLKVRDKDSRHNGEVTCKLEG-DVPFKILTSSRNTYKLVTDAVLDREQNPEYNITVTA 422

Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
            D G PP SS+  + + I D+ND+ PVF       +++EN+P G +I ++ A DPD GPN
Sbjct: 423 RDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVSASDPDLGPN 482

Query: 720 AVVHYSI 726
             V Y I
Sbjct: 483 GQVSYCI 489



 Score =  182 bits (444), Expect = 1e-43
 Identities = 119/389 (30%), Positives = 187/389 (48%), Gaps = 30/389 (7%)

Query: 8   HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
           H  + + D NDH+P F    +E  + E A  GT  +   A D DIG N    Y       
Sbjct: 118 HVNVEIEDINDHTPKFTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNY------- 170

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASPV 126
             L+P D           + +  + DG +   ++ +  LDREK   Y + + A D  +P 
Sbjct: 171 -QLSPSD--------HFSLINKEKSDGSKYPEMVLKTPLDREKQKSYHLTLTALDFGAP- 220

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
              LSSTA IHV + D NDN P FS+  Y VS+ E  +V     + ++ ATD D G N+ 
Sbjct: 221 --PLSSTAQIHVLVTDANDNAPVFSQDIYRVSLSE--NVYPGTTVLQVTATDQDEGVNAE 276

Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           I ++    +   QF ++S +G+++++ TLD+E+V+ Y +V+ A+DGG      T +  + 
Sbjct: 277 ITFSFSEASQITQFDLNSNTGEITVLNTLDFEEVKEYSIVLEARDGGGMIAQCTVE--VE 334

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
           + D NDNAP          + E+  +G  I  ++  D D   N E+T  +      G+V 
Sbjct: 335 VIDENDNAPEVIFQSLPNLIMEDAELGTHIALLKVRDKDSRHNGEVTCKL-----EGDVP 389

Query: 307 LPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
             I    R+ + + T   LDRE   +Y + VTA D G PP S++++              
Sbjct: 390 FKILTSSRNTYKLVTDAVLDREQNPEYNITVTARDRGKPPLSSSSSITLHIGDVNDNAPV 449

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDAD 394
           F    Y V +AE+ PPG  +  ++A+D D
Sbjct: 450 FSQSSYIVHVAENNPPGASISQVSASDPD 478



 Score =  175 bits (425), Expect = 2e-41
 Identities = 126/430 (29%), Positives = 212/430 (49%), Gaps = 22/430 (5%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F +   SG LL  + LDRE++           +A  V++   +   ++V I D ND+ P+
Sbjct: 75  FTVSAESGELLVSSRLDREEICGKKPACALEFEA--VAENPLNFYHVNVEIEDINDHTPK 132

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG-- 207
           F++ ++ + + E        ++    A DAD+G+N+   Y +   +     + +   G  
Sbjct: 133 FTQNSFELQISESAQPGTRFILGS--AHDADIGSNTLQNYQLSPSDHFSLINKEKSDGSK 190

Query: 208 --DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265
             ++ L   LD E+ +SY L + A D G+P  S+T Q+ + + D NDNAP F   +++ S
Sbjct: 191 YPEMVLKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDIYRVS 250

Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325
           +SENV  G ++++V A D DEGVNAE+T++ ++       DL    +  +G +     LD
Sbjct: 251 LSENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQFDL----NSNTGEITVLNTLD 306

Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
            E   +Y +++ A DGG      T                F        + ED   GT +
Sbjct: 307 FEEVKEYSIVLEARDGGGMIAQCTVEVEVIDENDNAPEVIFQ--SLPNLIMEDAELGTHI 364

Query: 386 VTLTATDADEDNRLHYEIT---GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
             L   D  +D+R + E+T    G+   +   +S+N   L+T A  LD +Q   Y +TV+
Sbjct: 365 ALLKVRD--KDSRHNGEVTCKLEGDVPFKILTSSRNTYKLVTDAV-LDREQNPEYNITVT 421

Query: 443 ATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
           A D G    S ++ + ++I D N+ APVF  + Y   V E+ P G ++  VSA+D D+G 
Sbjct: 422 ARDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVSASDPDLGP 481

Query: 501 NAQITYSLSS 510
           N Q++Y + S
Sbjct: 482 NGQVSYCIVS 491



 Score =  157 bits (380), Expect = 5e-36
 Identities = 117/384 (30%), Positives = 173/384 (45%), Gaps = 16/384 (4%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           V + I D N++ P F    +   + E A  GT  ++ SA D+D+G N    Y LS     
Sbjct: 119 VNVEIEDINDHTPKFTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHF 178

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
             +          P+    T    LDRE    Y LT+TA D G P LS T  + + V D 
Sbjct: 179 SLINKEKSDGSKYPEMVLKTP---LDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDA 235

Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634
           NDN PVF Q +Y  ++ E+   GT+V QV ATD D G+N  I +      +    F ++ 
Sbjct: 236 NDNAPVFSQDIYRVSLSENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQIT-QFDLNS 294

Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694
            +G I     LD E V  + +   A DGG      TV   +++ D ND+ P      L  
Sbjct: 295 NTGEITVLNTLDFEEVKEYSIVLEARDGGGMIAQCTV--EVEVIDENDNAPEVIFQSLPN 352

Query: 695 YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDL 754
            I E++ +GT I  ++  D D   N  V   ++G      F + T    +  +LVT   L
Sbjct: 353 LIMEDAELGTHIALLKVRDKDSRHNGEVTCKLEG---DVPFKILT-SSRNTYKLVTDAVL 408

Query: 755 DYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811
           D E    +Y + + A     PPL +   + + + DVNDNAPV      I +  ++  P  
Sbjct: 409 DREQ-NPEYNITVTARDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGA 467

Query: 812 PFGRVPAYDADV--TDKLQYRILS 833
              +V A D D+    ++ Y I+S
Sbjct: 468 SISQVSASDPDLGPNGQVSYCIVS 491



 Score =  132 bits (320), Expect = 1e-28
 Identities = 99/320 (30%), Positives = 148/320 (46%), Gaps = 22/320 (6%)

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           E+ P G+   VV    +D+G + Q   +    +S+E        F ++ ++G +  +  L
Sbjct: 39  EEMPKGS---VVGNLATDLGFSVQELPTRKLRVSSEK-----PYFTVSAESGELLVSSRL 90

Query: 540 DRETMSGYLLTVTARDGGVPSLS-DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
           DRE + G           V     +   V + + D+ND+ P F Q  +   I E A  GT
Sbjct: 91  DREEICGKKPACALEFEAVAENPLNFYHVNVEIEDINDHTPKFTQNSFELQISESAQPGT 150

Query: 599 SVSQVGATDADVGLNGRIHYELDPKDR-----EEGSFVIDPASGVIRTNKALDRESVATH 653
                 A DAD+G N   +Y+L P D      +E S        V++T   LDRE   ++
Sbjct: 151 RFILGSAHDADIGSNTLQNYQLSPSDHFSLINKEKSDGSKYPEMVLKT--PLDREKQKSY 208

Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713
            L   A+D G PP SST  +H+ + D ND+ PVF  D     +SEN   GTT+ ++ A D
Sbjct: 209 HLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDIYRVSLSENVYPGTTVLQVTATD 268

Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SP 772
            DEG NA + +S         F L +  G    E+  +  LD+E   K+Y +V+ A    
Sbjct: 269 QDEGVNAEITFSFSEASQITQFDLNSNTG----EITVLNTLDFEEV-KEYSIVLEARDGG 323

Query: 773 PLWNDVRVEILVTDVNDNAP 792
            +     VE+ V D NDNAP
Sbjct: 324 GMIAQCTVEVEVIDENDNAP 343



 Score =  126 bits (303), Expect = 1e-26
 Identities = 93/296 (31%), Positives = 146/296 (49%), Gaps = 34/296 (11%)

Query: 4   PFCIHQQINVL--DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
           P     QI+VL  D ND++PVF    Y  S+ E    GTTVL + ATDQD G NAE+ ++
Sbjct: 221 PLSSTAQIHVLVTDANDNAPVFSQDIYRVSLSENVYPGTTVLQVTATDQDEGVNAEITFS 280

Query: 62  IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121
               +  T                    F ++  +G +    +LD E+V  Y+++++A D
Sbjct: 281 FSEASQIT-------------------QFDLNSNTGEITVLNTLDFEEVKEYSIVLEARD 321

Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181
               ++       T+ V +ID+NDN P+   ++    + ED  +  +  IA +K  D D 
Sbjct: 322 GGGMIAQ-----CTVEVEVIDENDNAPEVIFQSLPNLIMEDAELGTH--IALLKVRDKDS 374

Query: 182 GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRS 238
             N  +   + G    + F I + S +   + T   LD EQ   Y + + A+D G P  S
Sbjct: 375 RHNGEVTCKLEG---DVPFKILTSSRNTYKLVTDAVLDREQNPEYNITVTARDRGKPPLS 431

Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294
           +++ + ++I DVNDNAP F  S +   V+EN P G SI +V A D D G N +++Y
Sbjct: 432 SSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVSASDPDLGPNGQVSY 487



 Score = 98.3 bits (234), Expect = 3e-18
 Identities = 77/271 (28%), Positives = 121/271 (44%), Gaps = 10/271 (3%)

Query: 626 EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI--KIEDINDS 683
           E+  F +   SG +  +  LDRE +      A A++     ++     H+  +IEDIND 
Sbjct: 71  EKPYFTVSAESGELLVSSRLDREEICGKK-PACALEFEAVAENPLNFYHVNVEIEDINDH 129

Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
            P F  +     ISE++  GT      AHD D G N + +Y +   D  +  + E   GS
Sbjct: 130 TPKFTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHFSLINKEKSDGS 189

Query: 744 DKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQII 800
              E+V    LD E  +K Y L + A    +PPL +  ++ +LVTD NDNAPV       
Sbjct: 190 KYPEMVLKTPLDREK-QKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDIYR 248

Query: 801 FNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTN 858
            +  ++ +P     +V A D D  V  ++ +     +      LN  TG +T+   L+  
Sbjct: 249 VSLSENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQFDLNSNTGEITVLNTLDFE 308

Query: 859 VPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889
             K  ++ +   DG   I A   + V +I E
Sbjct: 309 EVKEYSIVLEARDGGGMI-AQCTVEVEVIDE 338



 Score = 58.8 bits (136), Expect = 2e-06
 Identities = 44/116 (37%), Positives = 60/116 (51%), Gaps = 11/116 (9%)

Query: 243 LLINIRDVNDNAPR-FYTSLFQE--SVSENVPI----GYSIVRVQAYDADEGVNAELTYT 295
           L + + D NDNAPR  Y +L  +  ++ + VP     GY + +V A DAD G NA L+Y 
Sbjct: 492 LRVLVDDRNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYH 551

Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
           +      G   L +    R+G V T+  L      + +LLV   DGG PP SATAT
Sbjct: 552 VLQASEPGLFSLGL----RTGEVRTARALGDRDAVRQRLLVAVRDGGQPPLSATAT 603



 Score = 49.2 bits (112), Expect = 0.002
 Identities = 33/84 (39%), Positives = 47/84 (55%), Gaps = 3/84 (3%)

Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL-DRESVATHDL 655
           G  V++V A DAD G N  + Y +  +  E G F +   +G +RT +AL DR++V    L
Sbjct: 529 GYLVTKVVAVDADSGHNAWLSYHV-LQASEPGLFSLGLRTGEVRTARALGDRDAVRQRLL 587

Query: 656 KAVAIDGGTPPQSSTVIVHIKIED 679
            AV  DGG PP S+T  +H+   D
Sbjct: 588 VAVR-DGGQPPLSATATLHLVFAD 610



 Score = 44.8 bits (101), Expect = 0.035
 Identities = 26/81 (32%), Positives = 43/81 (53%), Gaps = 2/81 (2%)

Query: 170 VIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTL-DYEQVRSYRLVIR 228
           ++ K+ A DAD G N+ + Y ++  +    FS+   +G+V   + L D + VR  RL++ 
Sbjct: 531 LVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAVRQ-RLLVA 589

Query: 229 AQDGGSPSRSNTTQLLINIRD 249
            +DGG P  S T  L +   D
Sbjct: 590 VRDGGQPPLSATATLHLVFAD 610



 Score = 43.6 bits (98), Expect = 0.080
 Identities = 18/52 (34%), Positives = 29/52 (55%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
           +++ D ND++PVF    Y   V E    G ++  + A+D D+G N +V Y I
Sbjct: 438 LHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVSASDPDLGPNGQVSYCI 489



 Score = 37.5 bits (83), Expect = 5.3
 Identities = 39/127 (30%), Positives = 60/127 (47%), Gaps = 16/127 (12%)

Query: 455 VQINITDANNYAP-VFENA--PYTASVFEDAPI----GTTVLVVSATDSDVGINAQITYS 507
           +++ + D N+ AP V   A  P  +++F+  P     G  V  V A D+D G NA ++Y 
Sbjct: 492 LRVLVDDRNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYH 551

Query: 508 LSSEISNEAVAHHDQQFVINPQTGAITTNKLL-DRETMSGYLLTVTARDGGVPSLSDTTD 566
           +         A     F +  +TG + T + L DR+ +   LL V  RDGG P LS T  
Sbjct: 552 VLQ-------ASEPGLFSLGLRTGEVRTARALGDRDAVRQRLL-VAVRDGGQPPLSATAT 603

Query: 567 VEISVVD 573
           + +   D
Sbjct: 604 LHLVFAD 610


>UniRef50_A7SSF1 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 479

 Score =  210 bits (514), Expect = 3e-52
 Identities = 145/491 (29%), Positives = 233/491 (47%), Gaps = 34/491 (6%)

Query: 97  GALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT 156
           G +    SLD E+   + + + A D+  P S   ++ A + ++++D NDN P F    Y 
Sbjct: 7   GVITLTKSLDSERNTTFNLTITAHDKGMP-SLETATRAIVVIDVVDTNDNNPIFELSLYE 65

Query: 157 VSVDEDISVTDN-------PV---IAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206
            ++ E+ +   +       PV   I ++  +D D   NS +   ++ G+    F + S S
Sbjct: 66  TTILENTTAGSSVMVSEYAPVGQTILRLTVSDNDTAENSQLNLRVVSGDPNSTFFL-SNS 124

Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
           G++S+ + LDYE+++ Y L + A D G P         ++I IRD NDN P F   L++ 
Sbjct: 125 GEISIARKLDYERLQMYNLTVVAWDSGKPVLQSLKPANVVIRIRDDNDNQPVFSRDLYEA 184

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
            V EN+  G  +V+V+A DAD   N  L Y+M         +    ++  +G +Y S  L
Sbjct: 185 WVLENITAGQFVVQVKAKDADYQQNGRLVYSMVRN------NSKFRVNETTGEIYLSESL 238

Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
           D E   +Y   + A+D G  P+S++ +              F    Y+  + E+ P GT 
Sbjct: 239 DFEETKEYVFGIIASDSGVEPKSSSTSVRVIVMDVNDNVPTFDRFLYKSTVRENSPVGTT 298

Query: 385 VVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
            + + A D D   + ++ Y I  GNT   F I   +  G +TV + +DF+  + Y LT+ 
Sbjct: 299 AIKVQAIDTDTGSNAKIEYIIASGNTNNSFDI---DNHGFVTVNKAIDFETRKIYNLTIM 355

Query: 443 ATDSGGRSDTAMVQI--NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
           A D G    T++V +   I D N+  PVF+   Y   ++E+  I   ++ V A+DSD G 
Sbjct: 356 ARDCGDPVLTSIVSVVLLIEDENDNPPVFDLPYYFVRMYENVSIRADIIRVHASDSDSGF 415

Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560
           N++I YS         V    + F IN  TG I T   +D E    Y  +V A D G+P 
Sbjct: 416 NSEIRYSF-------PVGFVVKPFAINANTGMIYTRHEIDFEEKRVYEFSVIASDQGIPV 468

Query: 561 LSDTTDVEISV 571
           L D   V + V
Sbjct: 469 LRDVAIVRVDV 479



 Score =  210 bits (513), Expect = 4e-52
 Identities = 154/489 (31%), Positives = 239/489 (48%), Gaps = 34/489 (6%)

Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ--LLINIRDVNDNAPRFYTSLFQE 264
           G ++L K+LD E+  ++ L I A D G PS    T+  ++I++ D NDN P F  SL++ 
Sbjct: 7   GVITLTKSLDSERNTTFNLTITAHDKGMPSLETATRAIVVIDVVDTNDNNPIFELSLYET 66

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI---DPRS------ 315
           ++ EN   G S++ V  Y A  G    L  T++D D   N  L + +   DP S      
Sbjct: 67  TILENTTAGSSVM-VSEY-APVGQTI-LRLTVSDNDTAENSQLNLRVVSGDPNSTFFLSN 123

Query: 316 -GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT--ATXXXXXXXXXXXXXXFMPGQYE 372
            G +  + +LD E    Y L V A D G P   +   A               F    YE
Sbjct: 124 SGEISIARKLDYERLQMYNLTVVAWDSGKPVLQSLKPANVVIRIRDDNDNQPVFSRDLYE 183

Query: 373 VELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
             + E+   G  VV + A DAD  ++ RL Y +   N++ R + T+    G I +++ LD
Sbjct: 184 AWVLENITAGQFVVQVKAKDADYQQNGRLVYSMVRNNSKFRVNETT----GEIYLSESLD 239

Query: 431 FKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
           F++ + YV  + A+DSG   +S +  V++ + D N+  P F+   Y ++V E++P+GTT 
Sbjct: 240 FEETKEYVFGIIASDSGVEPKSSSTSVRVIVMDVNDNVPTFDRFLYKSTVRENSPVGTTA 299

Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
           + V A D+D G NA+I Y ++S  +N +       F I+   G +T NK +D ET   Y 
Sbjct: 300 IKVQAIDTDTGSNAKIEYIIASGNTNNS-------FDID-NHGFVTVNKAIDFETRKIYN 351

Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
           LT+ ARD G P L+    V + + D NDN PVF    Y   + E+  +   + +V A+D+
Sbjct: 352 LTIMARDCGDPVLTSIVSVVLLIEDENDNPPVFDLPYYFVRMYENVSIRADIIRVHASDS 411

Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
           D G N  I Y   P       F I+  +G+I T   +D E    ++   +A D G P   
Sbjct: 412 DSGFNSEIRYSF-PVGFVVKPFAINANTGMIYTRHEIDFEEKRVYEFSVIASDQGIPVLR 470

Query: 669 STVIVHIKI 677
              IV + +
Sbjct: 471 DVAIVRVDV 479



 Score =  194 bits (474), Expect = 2e-47
 Identities = 131/454 (28%), Positives = 226/454 (49%), Gaps = 26/454 (5%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI-ELVTADT 69
           I+V+D ND++P+FE+  YE ++ E  ++G++V+        + + A V  TI  L  +D 
Sbjct: 47  IDVVDTNDNNPIFELSLYETTILENTTAGSSVM--------VSEYAPVGQTILRLTVSDN 98

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
              E++              F +   SG +     LD E++  Y + V A D   PV   
Sbjct: 99  DTAENSQLNLRVVSGDPNSTFFLSN-SGEISIARKLDYERLQMYNLTVVAWDSGKPVLQS 157

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           L   A + + I DDNDN P FS   Y   V E+I  T    + ++KA DAD   N  + Y
Sbjct: 158 LKP-ANVVIRIRDDNDNQPVFSRDLYEAWVLENI--TAGQFVVQVKAKDADYQQNGRLVY 214

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
           +++  N++  F ++  +G++ L ++LD+E+ + Y   I A D G   +S++T + + + D
Sbjct: 215 SMVRNNSK--FRVNETTGEIYLSESLDFEETKEYVFGIIASDSGVEPKSSSTSVRVIVMD 272

Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
           VNDN P F   L++ +V EN P+G + ++VQA D D G NA++ Y +     +GN +   
Sbjct: 273 VNDNVPTFDRFLYKSTVRENSPVGTTAIKVQAIDTDTGSNAKIEYIIA----SGNTNNSF 328

Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            ID   G+V  +  +D ET+  Y L + A D GDP  ++  +              F   
Sbjct: 329 DID-NHGFVTVNKAIDFETRKIYNLTIMARDCGDPVLTSIVSVVLLIEDENDNPPVFDLP 387

Query: 370 QYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
            Y V + E+      ++ + A+D+D   ++ + Y    G     F+I +    G+I    
Sbjct: 388 YYFVRMYENVSIRADIIRVHASDSDSGFNSEIRYSFPVGFVVKPFAINANT--GMIYTRH 445

Query: 428 PLDFKQERRYVLTVSATDSG--GRSDTAMVQINI 459
            +DF+++R Y  +V A+D G     D A+V++++
Sbjct: 446 EIDFEEKRVYEFSVIASDQGIPVLRDVAIVRVDV 479



 Score =  194 bits (473), Expect = 3e-47
 Identities = 147/478 (30%), Positives = 232/478 (48%), Gaps = 42/478 (8%)

Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGRS----DTAMVQINITDANNYAPVFENAP 473
           N  G+IT+ + LD ++   + LT++A D G  S      A+V I++ D N+  P+FE + 
Sbjct: 4   NDYGVITLTKSLDSERNTTFNLTITAHDKGMPSLETATRAIVVIDVVDTNDNNPIFELSL 63

Query: 474 YTASVFED------------APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521
           Y  ++ E+            AP+G T+L ++ +D+D   N+Q+   + S   N       
Sbjct: 64  YETTILENTTAGSSVMVSEYAPVGQTILRLTVSDNDTAENSQLNLRVVSGDPNSTF---- 119

Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT--TDVEISVVDVNDNEP 579
             F+ N  +G I+  + LD E +  Y LTV A D G P L      +V I + D NDN+P
Sbjct: 120 --FLSN--SGEISIARKLDYERLQMYNLTVVAWDSGKPVLQSLKPANVVIRIRDDNDNQP 175

Query: 580 VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639
           VF + LY A ++E+   G  V QV A DAD   NGR+ Y +    R    F ++  +G I
Sbjct: 176 VFSRDLYEAWVLENITAGQFVVQVKAKDADYQQNGRLVYSMV---RNNSKFRVNETTGEI 232

Query: 640 RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699
             +++LD E    +    +A D G  P+SS+  V + + D+ND+ P F+       + EN
Sbjct: 233 YLSESLDFEETKEYVFGIIASDSGVEPKSSSTSVRVIVMDVNDNVPTFDRFLYKSTVREN 292

Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM-VDLDYES 758
           SP+GTT  +++A D D G NA + Y I  G+ +NSF +      D    VT+   +D+E+
Sbjct: 293 SPVGTTAIKVQAIDTDTGSNAKIEYIIASGNTNNSFDI------DNHGFVTVNKAIDFET 346

Query: 759 PRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR 815
            RK Y L I A     P L + V V +L+ D NDN PV          Y++        R
Sbjct: 347 -RKIYNLTIMARDCGDPVLTSIVSVVLLIEDENDNPPVFDLPYYFVRMYENVSIRADIIR 405

Query: 816 VPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
           V A D+D     +++Y    G       +N  TG +    +++    ++    V  +D
Sbjct: 406 VHASDSDSGFNSEIRYSFPVGFVVKPFAINANTGMIYTRHEIDFEEKRVYEFSVIASD 463



 Score = 98.7 bits (235), Expect = 2e-18
 Identities = 70/226 (30%), Positives = 115/226 (50%), Gaps = 25/226 (11%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ V+D ND+ P F+   Y+++VRE +  GTT + ++A D D G NA++EY I   + +T
Sbjct: 267 RVIVMDVNDNVPTFDRFLYKSTVRENSPVGTTAIKVQAIDTDTGSNAKIEYII--ASGNT 324

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            N                  F ID   G +    ++D E    Y + + A D   PV   
Sbjct: 325 NNS-----------------FDIDNH-GFVTVNKAIDFETRKIYNLTIMARDCGDPV--- 363

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           L+S  ++ + I D+NDN P F    Y V + E++S+  +  I ++ A+D+D G NS IRY
Sbjct: 364 LTSIVSVVLLIEDENDNPPVFDLPYYFVRMYENVSIRAD--IIRVHASDSDSGFNSEIRY 421

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP 235
           +   G     F+I++ +G +     +D+E+ R Y   + A D G P
Sbjct: 422 SFPVGFVVKPFAINANTGMIYTRHEIDFEEKRVYEFSVIASDQGIP 467



 Score = 71.7 bits (168), Expect = 3e-10
 Identities = 79/278 (28%), Positives = 126/278 (45%), Gaps = 34/278 (12%)

Query: 637 GVIRTNKALDRESVATHDLKAVAIDGGTPP--QSSTVIVHIKIEDINDSPPVFESDCL-- 692
           GVI   K+LD E   T +L   A D G P    ++  IV I + D ND+ P+FE      
Sbjct: 7   GVITLTKSLDSERNTTFNLTITAHDKGMPSLETATRAIVVIDVVDTNDNNPIFELSLYET 66

Query: 693 ----------TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
                     +  +SE +P+G TI  +   D D   N+ ++  +  GD +++F L     
Sbjct: 67  TILENTTAGSSVMVSEYAPVGQTILRLTVSDNDTAENSQLNLRVVSGDPNSTFFL----- 121

Query: 743 SDKAELVTMVDLDYESPRKKYELVIRA--ASPPLWNDVR---VEILVTDVNDNAPVMKDF 797
           S+  E+     LDYE   + Y L + A  +  P+   ++   V I + D NDN PV    
Sbjct: 122 SNSGEISIARKLDYER-LQMYNLTVVAWDSGKPVLQSLKPANVVIRIRDDNDNQPVFS-- 178

Query: 798 QIIFNNYK-DCFPVGPFG-RVPAYDADVTD--KLQYRILSGNNANLILLNETTGSMTLSP 853
           + ++  +  +    G F  +V A DAD     +L Y ++  N+     +NETTG + LS 
Sbjct: 179 RDLYEAWVLENITAGQFVVQVKAKDADYQQNGRLVYSMVRNNSK--FRVNETTGEIYLSE 236

Query: 854 QLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEM 891
            L+    K     +  +D   E K+    SVR+I  ++
Sbjct: 237 SLDFEETKEYVFGIIASDSGVEPKS-SSTSVRVIVMDV 273


>UniRef50_Q9BYE9 Cluster: Protocadherin LKC precursor; n=17;
           Theria|Rep: Protocadherin LKC precursor - Homo sapiens
           (Human)
          Length = 1310

 Score =  210 bits (514), Expect = 3e-52
 Identities = 214/767 (27%), Positives = 354/767 (46%), Gaps = 90/767 (11%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F +  ++G +   ++LD E +  + V +  +D    V   +       V + D NDN P 
Sbjct: 70  FAVTPKTGEVKLASALDYETLYTFKVTISVSDPYIQVQREML------VIVEDRNDNAPV 123

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI-----IGGNTQMQFSIDS 204
           F    ++ S++E + V    V+  + A D D+G+   + Y+I       G+++  F I +
Sbjct: 124 FQNTAFSTSINETLPV--GSVVFSVLAVDKDMGSAGMVVYSIEKVIPSTGDSEHLFRILA 181

Query: 205 LSGDVSLVKTLDYEQVRS-YRLVIRAQD-GGSPSRSNTTQ------LLINIRDVNDNAPR 256
            +G + L  +L Y    + Y+L ++A D GG    + T Q      L I++ D  D  P+
Sbjct: 182 -NGSIVLNGSLSYNNKSAFYQLELKACDLGGMYHNTFTIQCSLPVFLSISVVDQPDLDPQ 240

Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316
           F    +  SV+E+   G S++ V+A D D+G+N  + Y+++     G  D+        G
Sbjct: 241 FVREFYSASVAEDAAKGTSVLTVEAVDGDKGINDPVIYSISYSTRPGWFDIGA-----DG 295

Query: 317 WVYTSGQLDRE----TQAKYQLLVTATD------GGDPPRSATATXXXXXXXX------- 359
            +  +G LDRE       + QL VTAT+      G +   S   T               
Sbjct: 296 VIRVNGSLDREQLLEADEEVQLQVTATETHLNIYGQEAKVSIWVTVRVMDVNDHKPEFYN 355

Query: 360 -XXXXXXFMPGQYEVELA----EDEPPGTPV--VTLTATDADEDNRLHYEIT-GGNTRGR 411
                  F P + +V       E   P  P+  +T+   D D+ +   + ++ GG     
Sbjct: 356 CSLPACTFTPEEAQVNFTGYVDEHASPRIPIDDLTMVVYDPDKGSNGTFLLSLGGPDAEA 415

Query: 412 FSITSQNGRG------LITVAQPLDFKQERRYVLTVSATDSGGRS-DTAMVQINITDANN 464
           FS++ +   G      L+ V+  +D++++    + V ATDS  ++   AMV I++ D N+
Sbjct: 416 FSVSPERAAGSASVQVLVRVSALVDYERQTAMAVQVVATDSVSQNFSVAMVTIHLRDIND 475

Query: 465 YAPVFENAPYTASVFEDAPIGTTVL-VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523
           + P F  + Y  +V E +  G+ V   + ATD D G   QITYSL     N A       
Sbjct: 476 HRPTFPQSLYVLTVPEHSATGSVVTDSIHATDPDTGAWGQITYSLLP--GNGA-----DL 528

Query: 524 FVINPQTGAITTN--KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581
           F ++P +G +T    +LLDRE+ + Y LT+ A DGG  +LS +T ++I ++D+NDN PV 
Sbjct: 529 FQVDPVSGTVTVRNGELLDRESQAVYYLTLQATDGG--NLSSSTTLQIHLLDINDNAPVV 586

Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641
               Y   + E+    +   Q    D     N R+ + L P      +F +DP +G++R 
Sbjct: 587 SGS-YNIFVQEEEGNVSVTIQAHDNDEPGTNNSRLLFNLLPGPYSH-NFSLDPDTGLLRN 644

Query: 642 NKALDRESV-----ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696
              LDRE++         L  +  D G P   + V V I +EDIND+ P+F      F +
Sbjct: 645 LGPLDREAIDPALEGRIVLTVLVSDCGEPVLGTKVNVTITVEDINDNLPIFNQSSYNFTV 704

Query: 697 SENSPIGTTIGEIRAHDPDEGP-NAVVHYSIKGGDDSNSFSLETRQ-GSDKAE----LVT 750
            E  P G  +G ++A D D+   N  + +S+ G   +N F +     G+  AE    L  
Sbjct: 705 KEEDP-GVLVGVVKAWDADQTEANNRISFSLSGSG-ANYFMIRGLVLGAGWAEGYLRLPP 762

Query: 751 MVDLDYESPRKKYELVIRAASP-PLWNDVRVEILVT--DVNDNAPVM 794
            V LDYE+ +  + L + A +P P   +  V++ V   DVNDN P +
Sbjct: 763 DVSLDYET-QPVFNLTVSAENPDPQGGETIVDVCVNVKDVNDNPPTL 808



 Score =  190 bits (463), Expect = 5e-46
 Identities = 208/747 (27%), Positives = 330/747 (44%), Gaps = 78/747 (10%)

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
           P+F     +V + ED+     PV A+     A+   N  + Y +   N    F++   +G
Sbjct: 24  PKFLANMTSVILPEDL-----PVGAQAFWLVAEDQDNDPLTYGMSSPNAYF-FAVTPKTG 77

Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
           +V L   LDYE + ++++ I   D   P      ++L+ + D NDNAP F  + F  S++
Sbjct: 78  EVKLASALDYETLYTFKVTISVSD---PYIQVQREMLVIVEDRNDNAPVFQNTAFSTSIN 134

Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDK-DYTGNVDLPITIDPRSGWVYTSGQLDR 326
           E +P+G  +  V A D D G    + Y++      TG+ +    I   +G +  +G L  
Sbjct: 135 ETLPVGSVVFSVLAVDKDMGSAGMVVYSIEKVIPSTGDSEHLFRI-LANGSIVLNGSLSY 193

Query: 327 ETQ-AKYQLLVTATD-GGDPPRSATATXXXXXXXXXXXXXX------FMPGQYEVELAED 378
             + A YQL + A D GG    + T                      F+   Y   +AED
Sbjct: 194 NNKSAFYQLELKACDLGGMYHNTFTIQCSLPVFLSISVVDQPDLDPQFVREFYSASVAED 253

Query: 379 EPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ--- 433
              GT V+T+ A D D+  ++ + Y I+     G F I +    G+I V   LD +Q   
Sbjct: 254 AAKGTSVLTVEAVDGDKGINDPVIYSISYSTRPGWFDIGAD---GVIRVNGSLDREQLLE 310

Query: 434 -ERRYVLTVSATDS-----GGRSDTAM-VQINITDANNYAPVFENAPYTASVF--EDAPI 484
            +    L V+AT++     G  +  ++ V + + D N++ P F N    A  F  E+A +
Sbjct: 311 ADEEVQLQVTATETHLNIYGQEAKVSIWVTVRVMDVNDHKPEFYNCSLPACTFTPEEAQV 370

Query: 485 GTTVLVVSATDSDVGIN--AQITYSLSSEISNE---AVAHHDQQ-FVINPQTGA------ 532
             T  V       + I+    + Y      +     ++   D + F ++P+  A      
Sbjct: 371 NFTGYVDEHASPRIPIDDLTMVVYDPDKGSNGTFLLSLGGPDAEAFSVSPERAAGSASVQ 430

Query: 533 --ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590
             +  + L+D E  +   + V A D    + S    V I + D+ND+ P F Q LY   +
Sbjct: 431 VLVRVSALVDYERQTAMAVQVVATDSVSQNFS-VAMVTIHLRDINDHRPTFPQSLYVLTV 489

Query: 591 MEDALVGTSVSQ-VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI--RTNKALDR 647
            E +  G+ V+  + ATD D G  G+I Y L P +  +  F +DP SG +  R  + LDR
Sbjct: 490 PEHSATGSVVTDSIHATDPDTGAWGQITYSLLPGNGAD-LFQVDPVSGTVTVRNGELLDR 548

Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
           ES A + L   A DGG    S+T+ +H+   DIND+ PV       F   E   +  TI 
Sbjct: 549 ESQAVYYLTLQATDGGNLSSSTTLQIHLL--DINDNAPVVSGSYNIFVQEEEGNVSVTI- 605

Query: 708 EIRAHDPDEGP--NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE- 764
             +AHD DE    N+ + +++  G  S++FSL+     D   L  +  LD E+     E 
Sbjct: 606 --QAHDNDEPGTNNSRLLFNLLPGPYSHNFSLDP----DTGLLRNLGPLDREAIDPALEG 659

Query: 765 ------LVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA 818
                 LV     P L   V V I V D+NDN P+       F   K+  P    G V A
Sbjct: 660 RIVLTVLVSDCGEPVLGTKVNVTITVEDINDNLPIFNQSSYNF-TVKEEDPGVLVGVVKA 718

Query: 819 YDADVTD---KLQYRILSGNNANLILL 842
           +DAD T+   ++ +  LSG+ AN  ++
Sbjct: 719 WDADQTEANNRISFS-LSGSGANYFMI 744



 Score =  174 bits (423), Expect = 3e-41
 Identities = 221/775 (28%), Positives = 342/775 (44%), Gaps = 94/775 (12%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I+V+D  D  P F  + Y ASV E A+ GT+VLT++A D D G N  V Y+I   T    
Sbjct: 229 ISVVDQPDLDPQFVREFYSASVAEDAAKGTSVLTVEAVDGDKGINDPVIYSISYSTRPGW 288

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR----YTVLVKATDQASPV 126
                              F I G  G +    SLDRE++        + V AT+    +
Sbjct: 289 -------------------FDI-GADGVIRVNGSLDREQLLEADEEVQLQVTATETHLNI 328

Query: 127 SDRLSSTAT-IHVNIIDDNDNYPQF--------------SEKTYTVSVDEDISVTDNPVI 171
             + +  +  + V ++D ND+ P+F              ++  +T  VDE  S       
Sbjct: 329 YGQEAKVSIWVTVRVMDVNDHKPEFYNCSLPACTFTPEEAQVNFTGYVDEHASPRIPIDD 388

Query: 172 AKIKATDADVGANSAIRYAIIGGNTQMQFSI--DSLSGDVS---LVKT---LDYEQVRSY 223
             +   D D G+N     ++ GG     FS+  +  +G  S   LV+    +DYE+  + 
Sbjct: 389 LTMVVYDPDKGSNGTFLLSL-GGPDAEAFSVSPERAAGSASVQVLVRVSALVDYERQTAM 447

Query: 224 RLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV-RVQAY 282
            + + A D  S + S    + I++RD+ND+ P F  SL+  +V E+   G  +   + A 
Sbjct: 448 AVQVVATDSVSQNFS-VAMVTIHLRDINDHRPTFPQSLYVLTVPEHSATGSVVTDSIHAT 506

Query: 283 DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT-SGQL-DRETQAKYQLLVTATD 340
           D D G   ++TY++   +     DL   +DP SG V   +G+L DRE+QA Y L + ATD
Sbjct: 507 DPDTGAWGQITYSLLPGN---GADL-FQVDPVSGTVTVRNGELLDRESQAVYYLTLQATD 562

Query: 341 GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE----D 396
           GG+    +++T               + G Y + + E+E  G   VT+ A D DE    +
Sbjct: 563 GGN---LSSSTTLQIHLLDINDNAPVVSGSYNIFVQEEE--GNVSVTIQAHDNDEPGTNN 617

Query: 397 NRLHYEITGGNTRGRFSITSQNG--RGLITV-AQPLDFKQERRYVLTVSATDSGGRSDTA 453
           +RL + +  G     FS+    G  R L  +  + +D   E R VLTV  +D G      
Sbjct: 618 SRLLFNLLPGPYSHNFSLDPDTGLLRNLGPLDREAIDPALEGRIVLTVLVSDCGEPVLGT 677

Query: 454 MVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSS 510
            V + IT  D N+  P+F  + Y  +V E+ P G  V VV A D+D    N +I++SLS 
Sbjct: 678 KVNVTITVEDINDNLPIFNQSSYNFTVKEEDP-GVLVGVVKAWDADQTEANNRISFSLSG 736

Query: 511 EISNEAVAHHDQQFVINPQTGA----ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566
             +N  +    +  V+          +  +  LD ET   + LTV+A +          D
Sbjct: 737 SGANYFMI---RGLVLGAGWAEGYLRLPPDVSLDYETQPVFNLTVSAENPDPQGGETIVD 793

Query: 567 VEISVVDVNDNEPVFK-QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE------ 619
           V ++V DVNDN P      L    + E+      V+ V A+D D      I         
Sbjct: 794 VCVNVKDVNDNPPTLDVASLRGIRVAENGSQHGQVAVVVASDVDTSAQLEIQLVNILCTK 853

Query: 620 --LDPKDREEGSFVIDPASGV-IRTNKALDRES--VATHDLKA--VAIDGGTPPQSSTVI 672
             +D      G F +     V I  +KA+D E+  + T  ++A  +A D G    S+   
Sbjct: 854 AGVDVGSLCWGWFSVAANGSVYINQSKAIDYEACDLVTLVVRACDLATDPGFQAYSNNGS 913

Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPI-GTTIGEIRAHDPDEGPNAVVHYSI 726
           + I IED+ND+ P F  +  TF I     +    +  +RA D D G N V+ +SI
Sbjct: 914 LLITIEDVNDNAPYFLPENKTFVIIPELVLPNREVASVRARDDDSGNNGVILFSI 968



 Score =  167 bits (407), Expect = 3e-39
 Identities = 215/845 (25%), Positives = 342/845 (40%), Gaps = 97/845 (11%)

Query: 13  VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72
           V D ND++PVF+   +  S+ E    G+ V ++ A D+D+G    V Y+IE V   T + 
Sbjct: 114 VEDRNDNAPVFQNTAFSTSINETLPVGSVVFSVLAVDKDMGSAGMVVYSIEKVIPSTGDS 173

Query: 73  EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD---- 128
           E               +FRI      +L  +     K A Y + +KA D      +    
Sbjct: 174 EH--------------LFRILANGSIVLNGSLSYNNKSAFYQLELKACDLGGMYHNTFTI 219

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
           + S    + ++++D  D  PQF  + Y+ SV ED +   +  +  ++A D D G N  + 
Sbjct: 220 QCSLPVFLSISVVDQPDLDPQFVREFYSASVAEDAAKGTS--VLTVEAVDGDKGINDPVI 277

Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN--------T 240
           Y+I        F I +  G + +  +LD EQ+      ++ Q   + +  N        +
Sbjct: 278 YSISYSTRPGWFDIGA-DGVIRVNGSLDREQLLEADEEVQLQVTATETHLNIYGQEAKVS 336

Query: 241 TQLLINIRDVNDNAPRFY------------------TSLFQESVSENVPIGYSIVRVQAY 282
             + + + DVND+ P FY                  T    E  S  +PI    + +  Y
Sbjct: 337 IWVTVRVMDVNDHKPEFYNCSLPACTFTPEEAQVNFTGYVDEHASPRIPI--DDLTMVVY 394

Query: 283 DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG---WVYTSGQLDRETQAKYQLLVTAT 339
           D D+G N     ++   D       P      +     V  S  +D E Q    + V AT
Sbjct: 395 DPDKGSNGTFLLSLGGPDAEAFSVSPERAAGSASVQVLVRVSALVDYERQTAMAVQVVAT 454

Query: 340 DGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV-TLTATDADED-- 396
           D      S  A               F    Y + + E    G+ V  ++ ATD D    
Sbjct: 455 DSVSQNFSV-AMVTIHLRDINDHRPTFPQSLYVLTVPEHSATGSVVTDSIHATDPDTGAW 513

Query: 397 NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ 456
            ++ Y +  GN    F +   +G   +   + LD + +  Y LT+ ATD G  S +  +Q
Sbjct: 514 GQITYSLLPGNGADLFQVDPVSGTVTVRNGELLDRESQAVYYLTLQATDGGNLSSSTTLQ 573

Query: 457 INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNE 515
           I++ D N+ APV   + Y   V E+   G   + + A D+D  G N       S  + N 
Sbjct: 574 IHLLDINDNAPVVSGS-YNIFVQEEE--GNVSVTIQAHDNDEPGTNN------SRLLFNL 624

Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMSGYL-----LTVTARDGGVPSLSDTTDVEIS 570
               +   F ++P TG +     LDRE +   L     LTV   D G P L    +V I+
Sbjct: 625 LPGPYSHNFSLDPDTGLLRNLGPLDREAIDPALEGRIVLTVLVSDCGEPVLGTKVNVTIT 684

Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREE-- 627
           V D+NDN P+F Q  Y   + E+   G  V  V A DAD    N RI + L         
Sbjct: 685 VEDINDNLPIFNQSSYNFTVKEED-PGVLVGVVKAWDADQTEANNRISFSLSGSGANYFM 743

Query: 628 -GSFVIDP--ASGVIR--TNKALDRESVATHDLKAVAIDGGTPPQSSTVI-VHIKIEDIN 681
               V+    A G +R   + +LD E+    +L  V+ +   P    T++ V + ++D+N
Sbjct: 744 IRGLVLGAGWAEGYLRLPPDVSLDYETQPVFNL-TVSAENPDPQGGETIVDVCVNVKDVN 802

Query: 682 DSPPVFESDCLT-FYISENSPIGTTIGEIRAHDPDEGPNAVVH----YSIKGGDDSNS-- 734
           D+PP  +   L    ++EN      +  + A D D      +        K G D  S  
Sbjct: 803 DNPPTLDVASLRGIRVAENGSQHGQVAVVVASDVDTSAQLEIQLVNILCTKAGVDVGSLC 862

Query: 735 FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLW----NDVRVEILVTDV 787
           +   +   +    +     +DYE+      LV+RA   A+ P +    N+  + I + DV
Sbjct: 863 WGWFSVAANGSVYINQSKAIDYEA-CDLVTLVVRACDLATDPGFQAYSNNGSLLITIEDV 921

Query: 788 NDNAP 792
           NDNAP
Sbjct: 922 NDNAP 926



 Score =  154 bits (374), Expect = 3e-35
 Identities = 155/564 (27%), Positives = 256/564 (45%), Gaps = 54/564 (9%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV 425
           F+     V L ED P G     L A D D D  L Y ++  N    F++T + G   + +
Sbjct: 26  FLANMTSVILPEDLPVGAQAFWLVAEDQDNDP-LTYGMSSPNAYF-FAVTPKTGE--VKL 81

Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
           A  LD++    + +T+S +D   +    M+ I + D N+ APVF+N  ++ S+ E  P+G
Sbjct: 82  ASALDYETLYTFKVTISVSDPYIQVQREMLVI-VEDRNDNAPVFQNTAFSTSINETLPVG 140

Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
           + V  V A D D+G    + YS+   I +   + H  + + N   G+I  N  L     S
Sbjct: 141 SVVFSVLAVDKDMGSAGMVVYSIEKVIPSTGDSEHLFRILAN---GSIVLNGSLSYNNKS 197

Query: 546 G-YLLTVTARD-GGVPSLSDTTD------VEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
             Y L + A D GG+   + T        + ISVVD  D +P F ++ Y+A++ EDA  G
Sbjct: 198 AFYQLELKACDLGGMYHNTFTIQCSLPVFLSISVVDQPDLDPQFVREFYSASVAEDAAKG 257

Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD--- 654
           TSV  V A D D G+N  + Y +    R  G F I  A GVIR N +LDRE +   D   
Sbjct: 258 TSVLTVEAVDGDKGINDPVIYSISYSTR-PGWFDIG-ADGVIRVNGSLDREQLLEADEEV 315

Query: 655 -LKAVAIDGGT----PPQSSTVIVHIKIEDINDSPPVFESDCL--------------TFY 695
            L+  A +            ++ V +++ D+ND  P F +  L              T Y
Sbjct: 316 QLQVTATETHLNIYGQEAKVSIWVTVRVMDVNDHKPEFYNCSLPACTFTPEEAQVNFTGY 375

Query: 696 ISENSPIGTTIGEIR--AHDPDEGPNAVVHYSIKGGDDSNSFSL--ETRQGSDKAELVTM 751
           + E++     I ++    +DPD+G N     S+ GG D+ +FS+  E   GS   +++  
Sbjct: 376 VDEHASPRIPIDDLTMVVYDPDKGSNGTFLLSL-GGPDAEAFSVSPERAAGSASVQVLVR 434

Query: 752 VD--LDYE-SPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVM-KDFQIIFNNYKDC 807
           V   +DYE       ++V   +    ++   V I + D+ND+ P   +   ++       
Sbjct: 435 VSALVDYERQTAMAVQVVATDSVSQNFSVAMVTIHLRDINDHRPTFPQSLYVLTVPEHSA 494

Query: 808 FPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTL--SPQLNTNVPKLA 863
                   + A D D     ++ Y +L GN A+L  ++  +G++T+     L+     + 
Sbjct: 495 TGSVVTDSIHATDPDTGAWGQITYSLLPGNGADLFQVDPVSGTVTVRNGELLDRESQAVY 554

Query: 864 TMEVSVTDGVNEIKAMMQLSVRLI 887
            + +  TDG N + +   L + L+
Sbjct: 555 YLTLQATDGGN-LSSSTTLQIHLL 577



 Score =  117 bits (281), Expect = 5e-24
 Identities = 154/596 (25%), Positives = 239/596 (40%), Gaps = 73/596 (12%)

Query: 254 APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313
           AP+F  ++    + E++P+G     + A D D   N  LTY M+  +          + P
Sbjct: 23  APKFLANMTSVILPEDLPVGAQAFWLVAEDQD---NDPLTYGMSSPN-----AYFFAVTP 74

Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373
           ++G V  +  LD ET   +++ ++ +   DP                     F    +  
Sbjct: 75  KTGEVKLASALDYETLYTFKVTISVS---DPYIQVQREMLVIVEDRNDNAPVFQNTAFST 131

Query: 374 ELAEDEPPGTPVVTLTATDAD--EDNRLHYEI-----TGGNTRGRFSITSQNGRGLITVA 426
            + E  P G+ V ++ A D D      + Y I     + G++   F I +    G I + 
Sbjct: 132 SINETLPVGSVVFSVLAVDKDMGSAGMVVYSIEKVIPSTGDSEHLFRILA---NGSIVLN 188

Query: 427 QPLDFKQERR-YVLTVSATDSGGR-SDTAMVQ--------INITDANNYAPVFENAPYTA 476
             L +  +   Y L + A D GG   +T  +Q        I++ D  +  P F    Y+A
Sbjct: 189 GSLSYNNKSAFYQLELKACDLGGMYHNTFTIQCSLPVFLSISVVDQPDLDPQFVREFYSA 248

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
           SV EDA  GT+VL V A D D GIN  + YS+S        +     F I    G I  N
Sbjct: 249 SVAEDAAKGTSVLTVEAVDGDKGINDPVIYSIS-------YSTRPGWFDIGAD-GVIRVN 300

Query: 537 KLLDRETM----SGYLLTVTARDGGVPSLSDTTDVEI----SVVDVNDNEPVF------- 581
             LDRE +        L VTA +  +        V I     V+DVND++P F       
Sbjct: 301 GSLDREQLLEADEEVQLQVTATETHLNIYGQEAKVSIWVTVRVMDVNDHKPEFYNCSLPA 360

Query: 582 -------KQQLYTANIMEDALVGTSVSQVGAT--DADVGLNGRIHYELDPKDREEGSFVI 632
                   Q  +T  + E A     +  +     D D G NG     L   D E  S   
Sbjct: 361 CTFTPEEAQVNFTGYVDEHASPRIPIDDLTMVVYDPDKGSNGTFLLSLGGPDAEAFSVSP 420

Query: 633 DPASG------VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686
           + A+G      ++R +  +D E      ++ VA D       S  +V I + DIND  P 
Sbjct: 421 ERAAGSASVQVLVRVSALVDYERQTAMAVQVVATD-SVSQNFSVAMVTIHLRDINDHRPT 479

Query: 687 FESDCLTFYISENSPIGTTIGE-IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745
           F        + E+S  G+ + + I A DPD G    + YS+  G+ ++ F ++   G+  
Sbjct: 480 FPQSLYVLTVPEHSATGSVVTDSIHATDPDTGAWGQITYSLLPGNGADLFQVDPVSGTVT 539

Query: 746 AELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801
                +  LD ES    Y  +       L +   ++I + D+NDNAPV+     IF
Sbjct: 540 VRNGEL--LDRESQAVYYLTLQATDGGNLSSSTTLQIHLLDINDNAPVVSGSYNIF 593



 Score = 92.3 bits (219), Expect = 2e-16
 Identities = 123/520 (23%), Positives = 218/520 (41%), Gaps = 47/520 (9%)

Query: 459 ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518
           ++ A N AP F     +  + ED P+G     + A D D   N  +TY +SS        
Sbjct: 16  VSVAANVAPKFLANMTSVILPEDLPVGAQAFWLVAEDQD---NDPLTYGMSSP------- 65

Query: 519 HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578
            +   F + P+TG +     LD ET+  + +T++  D   P +    ++ + V D NDN 
Sbjct: 66  -NAYFFAVTPKTGEVKLASALDYETLYTFKVTISVSD---PYIQVQREMLVIVEDRNDNA 121

Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD---PKDREEGSFVIDPA 635
           PVF+   ++ +I E   VG+ V  V A D D+G  G + Y ++   P   +        A
Sbjct: 122 PVFQNTAFSTSINETLPVGSVVFSVLAVDKDMGSAGMVVYSIEKVIPSTGDSEHLFRILA 181

Query: 636 SGVIRTNKALD-RESVATHDLKAVAID-GG------TPPQSSTVIVHIKIEDINDSPPVF 687
           +G I  N +L      A + L+  A D GG      T   S  V + I + D  D  P F
Sbjct: 182 NGSIVLNGSLSYNNKSAFYQLELKACDLGGMYHNTFTIQCSLPVFLSISVVDQPDLDPQF 241

Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK-----GGDDSNSFSLETRQG 742
             +  +  ++E++  GT++  + A D D+G N  V YSI      G  D  +  +    G
Sbjct: 242 VREFYSASVAEDAAKGTSVLTVEAVDGDKGINDPVIYSISYSTRPGWFDIGADGVIRVNG 301

Query: 743 S-DKAELVTM---VDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQ 798
           S D+ +L+     V L   +      +  + A   +W  VR    V DVND+ P   +F 
Sbjct: 302 SLDREQLLEADEEVQLQVTATETHLNIYGQEAKVSIWVTVR----VMDVNDHKP---EF- 353

Query: 799 IIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSM-TLSPQLNT 857
             +N         P      +   V +    RI   ++  +++ +   GS  T    L  
Sbjct: 354 --YNCSLPACTFTPEEAQVNFTGYVDEHASPRI-PIDDLTMVVYDPDKGSNGTFLLSLGG 410

Query: 858 NVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFI 917
              +  ++      G   ++ ++++S  +  E     ++ V   D  ++ F   ++   +
Sbjct: 411 PDAEAFSVSPERAAGSASVQVLVRVSALVDYERQTAMAVQVVATDSVSQNFSVAMVTIHL 470

Query: 918 DGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPD 957
             +    P   +++Y+ +V + +  TG+++  S  A  PD
Sbjct: 471 RDINDHRPTFPQSLYVLTVPEHS-ATGSVVTDSIHATDPD 509



 Score = 50.8 bits (116), Expect = 5e-04
 Identities = 62/254 (24%), Positives = 105/254 (41%), Gaps = 32/254 (12%)

Query: 11   INVLDCNDHSPVFEMQQYEA-SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +NV D ND+ P  ++       V E  S    V  + A+D D     E++    L T   
Sbjct: 796  VNVKDVNDNPPTLDVASLRGIRVAENGSQHGQVAVVVASDVDTSAQLEIQLVNILCTKAG 855

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRA-SLDREKVARYTVLVKATDQAS-PVS 127
            ++                  F +       + ++ ++D E     T++V+A D A+ P  
Sbjct: 856  VD----------VGSLCWGWFSVAANGSVYINQSKAIDYEACDLVTLVVRACDLATDPGF 905

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
               S+  ++ + I D NDN P F  +  T  +  ++ V  N  +A ++A D D G N  I
Sbjct: 906  QAYSNNGSLLITIEDVNDNAPYFLPENKTFVIIPEL-VLPNREVASVRARDDDSGNNGVI 964

Query: 188  RYAII--------GGNTQMQ--FSI------DSLSGDVSLVKTLDYEQVRSYRLVIRAQD 231
             ++I+        G     Q  FSI      D  +G +  V +LD     +Y++ ++A+D
Sbjct: 965  LFSILRVDFISKDGATIPFQGVFSIFTSSEADVFAGSIQPVTSLDSTLQGTYQVTVQARD 1024

Query: 232  GGS--PSRSNTTQL 243
              S  P    TT L
Sbjct: 1025 RPSLGPFLEATTTL 1038


>UniRef50_Q47W44 Cluster: Cadherin domain protein; n=1; Colwellia
            psychrerythraea 34H|Rep: Cadherin domain protein -
            Colwellia psychrerythraea (strain 34H / ATCC BAA-681)
            (Vibriopsychroerythus)
          Length = 2193

 Score =  210 bits (513), Expect = 4e-52
 Identities = 217/884 (24%), Positives = 370/884 (41%), Gaps = 50/884 (5%)

Query: 34   EGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQD--VFR 91
            E A + T+     A D++ G + +V YT+      T N + A            D  +F 
Sbjct: 1099 EVAPTITSASIAAAIDENSGAS-QVVYTV----TSTDNGDIATGATVYSLKAGDDAALFT 1153

Query: 92   IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151
            I+  +GA+   A+ D E  A Y   V A+D A       S+   I ++I D +D  P  +
Sbjct: 1154 INSSTGAVTLTANPDDESKADYNFTVVASDAAGN-----STEQAITLDITDLDDVAPTIT 1208

Query: 152  EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSL 211
              T   ++DE+       V+  + +TD+   A     Y++  G+    F+I+S SG V+L
Sbjct: 1209 SATTATALDENSGA--GQVVYTVTSTDSGDIATGVTVYSLKAGDDAALFTINSSSGAVTL 1266

Query: 212  VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271
                D E    Y   + A DG   S    T L  +I D+++ AP   ++    ++ EN  
Sbjct: 1267 TANPDDESKADYNFTVVASDGAGNSSEKVTTL--DITDLDEVAPTITSASSATALDENSG 1324

Query: 272  IGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK 331
             G  +  V + D+ +       Y++   D         TI+  +G V  +   D E++A 
Sbjct: 1325 AGQVVYTVTSTDSGDIATGATAYSLKASDDAAL----FTINSSTGAVTLTANPDDESKAD 1380

Query: 332  YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTAT 391
            Y   V A+DG     S                         + L E+   G  V T+T+T
Sbjct: 1381 YNFTVVASDGAG--NSTEQAITLDIIDLDDVAPTITSASSAIALDENSGAGQVVYTVTST 1438

Query: 392  DADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR 449
            D  +       Y +  G+    F+I S  G   +T A P D + +  Y  TV A+D  G 
Sbjct: 1439 DNGDIATGATTYSLKAGDDAALFTINSSTGAVTLT-ANP-DDESKADYNFTVVASDGAGN 1496

Query: 450  SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509
            S    + ++ITD +   P+  +A    ++ E++  G  V  V++TD+        TYSL 
Sbjct: 1497 SSEKAITLDITDLDEVGPIITSASSATALDENSGAGQVVYTVTSTDNGDIATGATTYSLK 1556

Query: 510  SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569
               S + VA     F IN  TGA+T     D E+ + Y  TV A DG     S    + +
Sbjct: 1557 ---SGDDVA----LFTINSSTGAVTLTADPDDESKADYNFTVVASDGA--GNSSEKAITL 1607

Query: 570  SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD-ADVGLNGRIHYELDPKDREEG 628
             ++D+++  P        A I E++  G  V  V +TD  D+  +    Y L   D +  
Sbjct: 1608 DIIDLDEVAPTITSAAIAAAIDENSGAGQVVYTVMSTDNGDIATDATT-YSLKSGD-DAA 1665

Query: 629  SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688
             F I+ ++G +      D E  A ++   VA DG     SS   + + I D+++  P   
Sbjct: 1666 LFTINSSTGAVTLTANPDDEGKANYNFTVVASDGA--GNSSEKAITLDITDLDEVAPTIT 1723

Query: 689  SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAEL 748
            S      I ENS  G  +  + + D  +       YS+K  DD+  F++ +  G+     
Sbjct: 1724 SASSATAIDENSGAGQVVYTVTSTDSGDIATGATLYSLKAVDDAALFTINSTSGA----- 1778

Query: 749  VTMVDLDYESPRKKYELVIRAASPPLWNDVR-VEILVTDVNDNAPVMKDFQIIFNNYKDC 807
            VT+     +  +  Y   + A   P  N  + V + +TD+++ AP +          ++ 
Sbjct: 1779 VTLTANPNDETKADYNFTVVATDSPGNNSEKAVTLDITDLDEIAPTITSAATATAIDENS 1838

Query: 808  FPVGPFGRVPAYDA-DVT-DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATM 865
                    V + D+ DV      Y + +G++A L  +N +TG++TL+   +       + 
Sbjct: 1839 GAGQVVYTVTSTDSGDVAIGATVYSLKTGDDAALFTINSSTGAVTLTANPDDETKADYSF 1898

Query: 866  EVSVTD-GVNEIKAMMQLSVRLITE-EMLLNSITVRLNDMTAEQ 907
             V  TD G N  + ++ L +  + E   ++NS+ +   D+   +
Sbjct: 1899 IVVATDTGNNSSEQVVTLDINDLDEVAPIINSVVLSDTDLAKSE 1942



 Score =  209 bits (511), Expect = 7e-52
 Identities = 208/849 (24%), Positives = 359/849 (42%), Gaps = 62/849 (7%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            ++++D +D +P         ++ E + +G  V T+ +TD D   +   +Y+++  T D  
Sbjct: 680  LDIIDLDDVAPTITSASSATALDENSGAGQVVYTVTSTDSDDVSSGSTDYSLK--TGD-- 735

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
               DA             +F I+  +GA+   A  D E  A Y   V A+D A       
Sbjct: 736  ---DAA------------LFTINSSTGAVTLSADPDDETKADYNFTVVASDSAGN----- 775

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S+   I ++IID ++  P  +      ++DE+       V+  + +TD+   A  A  Y+
Sbjct: 776  STEQAITLDIIDLDEVAPTITSTAIAAALDENSGA--GQVVYTVTSTDSGDIATGATAYS 833

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            +  G+    F+I+S +G+V+L+   D E    Y   + A D  S   S    + ++I D+
Sbjct: 834  LKIGDDAALFTINSGTGEVTLIANPDDETKADYNFTVVASD--SAGNSTEQAITLDITDL 891

Query: 251  NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
            +D AP   +S+   ++ EN  +G  +  V + D+ +       Y++      G+     T
Sbjct: 892  DDVAPTITSSVTATAIDENSGVGQVVYTVTSTDSGDIATGVTAYSLK----AGDDAALFT 947

Query: 311  IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
            I+  +G V  +   D ET+A Y   V ATD      S+                      
Sbjct: 948  INSSTGAVTLTANPDDETKADYSFTVVATDTAG--NSSEQVITLDITDLDEVAPTITSAS 1005

Query: 371  YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
                L E+   G  V T+T+TD+ +       Y +   +    F+I S  G   +T A P
Sbjct: 1006 SATALDENSGAGQVVYTVTSTDSGDIATGATAYSLKTSDDAALFTINSSTGAVTLT-ANP 1064

Query: 429  LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
             D +    Y  TV ATD+ G S    + ++ITD +  AP   +A   A++ E++     V
Sbjct: 1065 -DDEIRADYNFTVVATDTAGNSREQSITLDITDLDEVAPTITSASIAAAIDENSGASQVV 1123

Query: 489  LVVSATDS-DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
              V++TD+ D+   A + YSL +   ++A       F IN  TGA+T     D E+ + Y
Sbjct: 1124 YTVTSTDNGDIATGATV-YSLKA--GDDAAL-----FTINSSTGAVTLTANPDDESKADY 1175

Query: 548  LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
              TV A D    S      + + + D++D  P          + E++  G  V  V +TD
Sbjct: 1176 NFTVVASDAAGNSTEQA--ITLDITDLDDVAPTITSATTATALDENSGAGQVVYTVTSTD 1233

Query: 608  ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
            +     G   Y L   D +   F I+ +SG +      D ES A ++   VA DG     
Sbjct: 1234 SGDIATGVTVYSLKAGD-DAALFTINSSSGAVTLTANPDDESKADYNFTVVASDGAG--N 1290

Query: 668  SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
            SS  +  + I D+++  P   S      + ENS  G  +  + + D  +       YS+K
Sbjct: 1291 SSEKVTTLDITDLDEVAPTITSASSATALDENSGAGQVVYTVTSTDSGDIATGATAYSLK 1350

Query: 728  GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEIL--VT 785
              DD+  F++ +  G+     VT+     +  +  Y   +  AS    N     I   + 
Sbjct: 1351 ASDDAALFTINSSTGA-----VTLTANPDDESKADYNFTV-VASDGAGNSTEQAITLDII 1404

Query: 786  DVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD-ADV-TDKLQYRILSGNNANLILLN 843
            D++D AP +          ++         V + D  D+ T    Y + +G++A L  +N
Sbjct: 1405 DLDDVAPTITSASSAIALDENSGAGQVVYTVTSTDNGDIATGATTYSLKAGDDAALFTIN 1464

Query: 844  ETTGSMTLS 852
             +TG++TL+
Sbjct: 1465 SSTGAVTLT 1473



 Score =  200 bits (487), Expect = 6e-49
 Identities = 197/817 (24%), Positives = 346/817 (42%), Gaps = 40/817 (4%)

Query: 40   TTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL 99
            T+ +T  A D++ G   +V YT+   + D+ +                 +F I+  +GA+
Sbjct: 899  TSSVTATAIDENSGVG-QVVYTV--TSTDSGDIATGVTAYSLKAGDDAALFTINSSTGAV 955

Query: 100  LTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSV 159
               A+ D E  A Y+  V ATD A   S+++     I ++I D ++  P  +  +   ++
Sbjct: 956  TLTANPDDETKADYSFTVVATDTAGNSSEQV-----ITLDITDLDEVAPTITSASSATAL 1010

Query: 160  DEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQ 219
            DE+       V+  + +TD+   A  A  Y++   +    F+I+S +G V+L    D E 
Sbjct: 1011 DENSGA--GQVVYTVTSTDSGDIATGATAYSLKTSDDAALFTINSSTGAVTLTANPDDEI 1068

Query: 220  VRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRV 279
               Y   + A D    SR  +  + ++I D+++ AP   ++    ++ EN      +  V
Sbjct: 1069 RADYNFTVVATDTAGNSREQS--ITLDITDLDEVAPTITSASIAAAIDENSGASQVVYTV 1126

Query: 280  QAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTAT 339
             + D  +       Y++      G+     TI+  +G V  +   D E++A Y   V A+
Sbjct: 1127 TSTDNGDIATGATVYSLK----AGDDAALFTINSSTGAVTLTANPDDESKADYNFTVVAS 1182

Query: 340  DGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DN 397
            D      S                           L E+   G  V T+T+TD+ +    
Sbjct: 1183 DAAG--NSTEQAITLDITDLDDVAPTITSATTATALDENSGAGQVVYTVTSTDSGDIATG 1240

Query: 398  RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQI 457
               Y +  G+    F+I S +G   +T A P D + +  Y  TV A+D  G S   +  +
Sbjct: 1241 VTVYSLKAGDDAALFTINSSSGAVTLT-ANP-DDESKADYNFTVVASDGAGNSSEKVTTL 1298

Query: 458  NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517
            +ITD +  AP   +A    ++ E++  G  V  V++TDS         YSL +  S++A 
Sbjct: 1299 DITDLDEVAPTITSASSATALDENSGAGQVVYTVTSTDSGDIATGATAYSLKA--SDDAA 1356

Query: 518  AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577
                  F IN  TGA+T     D E+ + Y  TV A DG   S      + + ++D++D 
Sbjct: 1357 L-----FTINSSTGAVTLTANPDDESKADYNFTVVASDGAGNSTEQA--ITLDIIDLDDV 1409

Query: 578  EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637
             P          + E++  G  V  V +TD      G   Y L   D +   F I+ ++G
Sbjct: 1410 APTITSASSAIALDENSGAGQVVYTVTSTDNGDIATGATTYSLKAGD-DAALFTINSSTG 1468

Query: 638  VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697
             +      D ES A ++   VA DG     SS   + + I D+++  P+  S      + 
Sbjct: 1469 AVTLTANPDDESKADYNFTVVASDGAG--NSSEKAITLDITDLDEVGPIITSASSATALD 1526

Query: 698  ENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757
            ENS  G  +  + + D  +       YS+K GDD   F++ +  G+    +    D D E
Sbjct: 1527 ENSGAGQVVYTVTSTDNGDIATGATTYSLKSGDDVALFTINSSTGA----VTLTADPDDE 1582

Query: 758  SPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVP 817
            S       V+ +      ++  + + + D+++ AP +    I     ++         V 
Sbjct: 1583 SKADYNFTVVASDGAGNSSEKAITLDIIDLDEVAPTITSAAIAAAIDENSGAGQVVYTVM 1642

Query: 818  AYD-ADV-TDKLQYRILSGNNANLILLNETTGSMTLS 852
            + D  D+ TD   Y + SG++A L  +N +TG++TL+
Sbjct: 1643 STDNGDIATDATTYSLKSGDDAALFTINSSTGAVTLT 1679



 Score =  197 bits (480), Expect = 4e-48
 Identities = 205/854 (24%), Positives = 356/854 (41%), Gaps = 46/854 (5%)

Query: 34   EGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRID 93
            E A + T+  +  A D++ G   +V YT+   + D+ +                 +F I+
Sbjct: 996  EVAPTITSASSATALDENSGAG-QVVYTV--TSTDSGDIATGATAYSLKTSDDAALFTIN 1052

Query: 94   GRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEK 153
              +GA+   A+ D E  A Y   V ATD A       S   +I ++I D ++  P  +  
Sbjct: 1053 SSTGAVTLTANPDDEIRADYNFTVVATDTAGN-----SREQSITLDITDLDEVAPTITSA 1107

Query: 154  TYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVK 213
            +   ++DE+   +   V+  + +TD    A  A  Y++  G+    F+I+S +G V+L  
Sbjct: 1108 SIAAAIDENSGASQ--VVYTVTSTDNGDIATGATVYSLKAGDDAALFTINSSTGAVTLTA 1165

Query: 214  TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIG 273
              D E    Y   + A D    S      + ++I D++D AP   ++    ++ EN   G
Sbjct: 1166 NPDDESKADYNFTVVASDAAGNSTEQA--ITLDITDLDDVAPTITSATTATALDENSGAG 1223

Query: 274  YSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQ 333
              +  V + D+ +       Y++      G+     TI+  SG V  +   D E++A Y 
Sbjct: 1224 QVVYTVTSTDSGDIATGVTVYSLK----AGDDAALFTINSSSGAVTLTANPDDESKADYN 1279

Query: 334  LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393
              V A+DG     S+                          L E+   G  V T+T+TD+
Sbjct: 1280 FTVVASDGAG--NSSEKVTTLDITDLDEVAPTITSASSATALDENSGAGQVVYTVTSTDS 1337

Query: 394  DE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSD 451
             +       Y +   +    F+I S  G   +T A P D + +  Y  TV A+D  G S 
Sbjct: 1338 GDIATGATAYSLKASDDAALFTINSSTGAVTLT-ANP-DDESKADYNFTVVASDGAGNST 1395

Query: 452  TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE 511
               + ++I D ++ AP   +A    ++ E++  G  V  V++TD+        TYSL + 
Sbjct: 1396 EQAITLDIIDLDDVAPTITSASSAIALDENSGAGQVVYTVTSTDNGDIATGATTYSLKA- 1454

Query: 512  ISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571
              ++A       F IN  TGA+T     D E+ + Y  TV A DG     S    + + +
Sbjct: 1455 -GDDAAL-----FTINSSTGAVTLTANPDDESKADYNFTVVASDGA--GNSSEKAITLDI 1506

Query: 572  VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631
             D+++  P+         + E++  G  V  V +TD      G   Y L   D +   F 
Sbjct: 1507 TDLDEVGPIITSASSATALDENSGAGQVVYTVTSTDNGDIATGATTYSLKSGD-DVALFT 1565

Query: 632  IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691
            I+ ++G +      D ES A ++   VA DG     SS   + + I D+++  P   S  
Sbjct: 1566 INSSTGAVTLTADPDDESKADYNFTVVASDGAG--NSSEKAITLDIIDLDEVAPTITSAA 1623

Query: 692  LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751
            +   I ENS  G  +  + + D  +       YS+K GDD+  F++ +  G+     VT+
Sbjct: 1624 IAAAIDENSGAGQVVYTVMSTDNGDIATDATTYSLKSGDDAALFTINSSTGA-----VTL 1678

Query: 752  VDLDYESPRKKYELVIRAASPPLWN--DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809
                 +  +  Y   +  AS    N  +  + + +TD+++ AP +          ++   
Sbjct: 1679 TANPDDEGKANYNFTV-VASDGAGNSSEKAITLDITDLDEVAPTITSASSATAIDENSGA 1737

Query: 810  VGPFGRVPAYDA-DV-TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867
                  V + D+ D+ T    Y + + ++A L  +N T+G++TL+   N          V
Sbjct: 1738 GQVVYTVTSTDSGDIATGATLYSLKAVDDAALFTINSTSGAVTLTANPNDETKADYNFTV 1797

Query: 868  SVTD--GVNEIKAM 879
              TD  G N  KA+
Sbjct: 1798 VATDSPGNNSEKAV 1811



 Score =  196 bits (478), Expect = 7e-48
 Identities = 184/770 (23%), Positives = 329/770 (42%), Gaps = 41/770 (5%)

Query: 89   VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
            +F I+  +G ++  A+ D E  A Y   + A+D A  +S++     ++  +I D ++  P
Sbjct: 533  LFAINSSTGTVILTANPDYESKADYNFTLVASDPAGNISEQ-----SVTFDITDLDEVAP 587

Query: 149  QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
              +  +   ++DE+       V+  + +TD+      A  Y++  G+    F+I+S +G 
Sbjct: 588  TITSASTASTIDENSG--SGQVVYTVTSTDSSDITTGATSYSLKAGDDAALFNINSSTGA 645

Query: 209  VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268
            V+L    D E    Y   + A D    SR     + ++I D++D AP   ++    ++ E
Sbjct: 646  VTLTADPDDETKADYNFTVLASDAAGNSREQA--ITLDIIDLDDVAPTITSASSATALDE 703

Query: 269  NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328
            N   G  +  V + D+D+  +    Y++     TG+     TI+  +G V  S   D ET
Sbjct: 704  NSGAGQVVYTVTSTDSDDVSSGSTDYSLK----TGDDAALFTINSSTGAVTLSADPDDET 759

Query: 329  QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388
            +A Y   V A+D      S                           L E+   G  V T+
Sbjct: 760  KADYNFTVVASDSAG--NSTEQAITLDIIDLDEVAPTITSTAIAAALDENSGAGQVVYTV 817

Query: 389  TATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446
            T+TD+ +       Y +  G+    F+I S  G G +T+    D + +  Y  TV A+DS
Sbjct: 818  TSTDSGDIATGATAYSLKIGDDAALFTINS--GTGEVTLIANPDDETKADYNFTVVASDS 875

Query: 447  GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506
             G S    + ++ITD ++ AP   ++    ++ E++ +G  V  V++TDS         Y
Sbjct: 876  AGNSTEQAITLDITDLDDVAPTITSSVTATAIDENSGVGQVVYTVTSTDSGDIATGVTAY 935

Query: 507  SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566
            SL +   ++A       F IN  TGA+T     D ET + Y  TV A D      S    
Sbjct: 936  SLKA--GDDAAL-----FTINSSTGAVTLTANPDDETKADYSFTVVATD--TAGNSSEQV 986

Query: 567  VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE 626
            + + + D+++  P          + E++  G  V  V +TD+     G   Y L   D +
Sbjct: 987  ITLDITDLDEVAPTITSASSATALDENSGAGQVVYTVTSTDSGDIATGATAYSLKTSD-D 1045

Query: 627  EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686
               F I+ ++G +      D E  A ++   VA D  T   S    + + I D+++  P 
Sbjct: 1046 AALFTINSSTGAVTLTANPDDEIRADYNFTVVATD--TAGNSREQSITLDITDLDEVAPT 1103

Query: 687  FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746
              S  +   I ENS     +  + + D  +       YS+K GDD+  F++ +  G+   
Sbjct: 1104 ITSASIAAAIDENSGASQVVYTVTSTDNGDIATGATVYSLKAGDDAALFTINSSTGA--- 1160

Query: 747  ELVTMVDLDYESPRKKYELVIRAASPPLWNDVR--VEILVTDVNDNAPVMKDFQIIFNNY 804
              VT+     +  +  Y   +  AS    N     + + +TD++D AP +          
Sbjct: 1161 --VTLTANPDDESKADYNFTV-VASDAAGNSTEQAITLDITDLDDVAPTITSATTATALD 1217

Query: 805  KDCFPVGPFGRVPAYDA-DV-TDKLQYRILSGNNANLILLNETTGSMTLS 852
            ++         V + D+ D+ T    Y + +G++A L  +N ++G++TL+
Sbjct: 1218 ENSGAGQVVYTVTSTDSGDIATGVTVYSLKAGDDAALFTINSSSGAVTLT 1267



 Score =  175 bits (425), Expect = 2e-41
 Identities = 164/671 (24%), Positives = 285/671 (42%), Gaps = 35/671 (5%)

Query: 188  RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD-GGSPSRSNTTQLLIN 246
            R+++ G +  + F+I+S +G V L    DYE    Y   + A D  G+ S  + T    +
Sbjct: 523  RFSLTGDDASL-FAINSSTGTVILTANPDYESKADYNFTLVASDPAGNISEQSVT---FD 578

Query: 247  IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            I D+++ AP   ++    ++ EN   G  +  V + D+ +      +Y++      G+  
Sbjct: 579  ITDLDEVAPTITSASTASTIDENSGSGQVVYTVTSTDSSDITTGATSYSLK----AGDDA 634

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
                I+  +G V  +   D ET+A Y   V A+D     R    T               
Sbjct: 635  ALFNINSSTGAVTLTADPDDETKADYNFTVLASDAAGNSREQAIT--LDIIDLDDVAPTI 692

Query: 367  MPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLIT 424
                    L E+   G  V T+T+TD+D+       Y +  G+    F+I S    G +T
Sbjct: 693  TSASSATALDENSGAGQVVYTVTSTDSDDVSSGSTDYSLKTGDDAALFTINSST--GAVT 750

Query: 425  VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
            ++   D + +  Y  TV A+DS G S    + ++I D +  AP   +    A++ E++  
Sbjct: 751  LSADPDDETKADYNFTVVASDSAGNSTEQAITLDIIDLDEVAPTITSTAIAAALDENSGA 810

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
            G  V  V++TDS         YSL  +I ++A       F IN  TG +T     D ET 
Sbjct: 811  GQVVYTVTSTDSGDIATGATAYSL--KIGDDAAL-----FTINSGTGEVTLIANPDDETK 863

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
            + Y  TV A D    S      + + + D++D  P     +    I E++ VG  V  V 
Sbjct: 864  ADYNFTVVASDSAGNSTEQA--ITLDITDLDDVAPTITSSVTATAIDENSGVGQVVYTVT 921

Query: 605  ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            +TD+     G   Y L   D +   F I+ ++G +      D E+ A +    VA D  T
Sbjct: 922  STDSGDIATGVTAYSLKAGD-DAALFTINSSTGAVTLTANPDDETKADYSFTVVATD--T 978

Query: 665  PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
               SS  ++ + I D+++  P   S      + ENS  G  +  + + D  +       Y
Sbjct: 979  AGNSSEQVITLDITDLDEVAPTITSASSATALDENSGAGQVVYTVTSTDSGDIATGATAY 1038

Query: 725  SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL-VIRAASPPLWNDVRVEIL 783
            S+K  DD+  F++ +  G+     VT+     +  R  Y   V+   +     +  + + 
Sbjct: 1039 SLKTSDDAALFTINSSTGA-----VTLTANPDDEIRADYNFTVVATDTAGNSREQSITLD 1093

Query: 784  VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD-ADV-TDKLQYRILSGNNANLIL 841
            +TD+++ AP +    I     ++         V + D  D+ T    Y + +G++A L  
Sbjct: 1094 ITDLDEVAPTITSASIAAAIDENSGASQVVYTVTSTDNGDIATGATVYSLKAGDDAALFT 1153

Query: 842  LNETTGSMTLS 852
            +N +TG++TL+
Sbjct: 1154 INSSTGAVTLT 1164



 Score =  141 bits (342), Expect = 2e-31
 Identities = 137/575 (23%), Positives = 242/575 (42%), Gaps = 26/575 (4%)

Query: 302  TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
            TG+      I+  +G V  +   D E++A Y   + A+D        + T          
Sbjct: 527  TGDDASLFAINSSTGTVILTANPDYESKADYNFTLVASDPAGNISEQSVTFDITDLDEVA 586

Query: 362  XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNG 419
                       ++  E+   G  V T+T+TD+ +       Y +  G+    F+I S  G
Sbjct: 587  PTITSASTASTID--ENSGSGQVVYTVTSTDSSDITTGATSYSLKAGDDAALFNINSSTG 644

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479
               +T A P D + +  Y  TV A+D+ G S    + ++I D ++ AP   +A    ++ 
Sbjct: 645  AVTLT-ADP-DDETKADYNFTVLASDAAGNSREQAITLDIIDLDDVAPTITSASSATALD 702

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
            E++  G  V  V++TDSD   +    YSL +   ++A       F IN  TGA+T +   
Sbjct: 703  ENSGAGQVVYTVTSTDSDDVSSGSTDYSLKT--GDDAAL-----FTINSSTGAVTLSADP 755

Query: 540  DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
            D ET + Y  TV A D    S      + + ++D+++  P        A + E++  G  
Sbjct: 756  DDETKADYNFTVVASDSAGNSTEQA--ITLDIIDLDEVAPTITSTAIAAALDENSGAGQV 813

Query: 600  VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
            V  V +TD+     G   Y L   D +   F I+  +G +      D E+ A ++   VA
Sbjct: 814  VYTVTSTDSGDIATGATAYSLKIGD-DAALFTINSGTGEVTLIANPDDETKADYNFTVVA 872

Query: 660  IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
             D      S+   + + I D++D  P   S      I ENS +G  +  + + D  +   
Sbjct: 873  SDSAG--NSTEQAITLDITDLDDVAPTITSSVTATAIDENSGVGQVVYTVTSTDSGDIAT 930

Query: 720  AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR 779
             V  YS+K GDD+  F++ +  G+     VT+     +  +  Y   + A      +  +
Sbjct: 931  GVTAYSLKAGDDAALFTINSSTGA-----VTLTANPDDETKADYSFTVVATDTAGNSSEQ 985

Query: 780  VEIL-VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDA-DV-TDKLQYRILSGNN 836
            V  L +TD+++ AP +          ++         V + D+ D+ T    Y + + ++
Sbjct: 986  VITLDITDLDEVAPTITSASSATALDENSGAGQVVYTVTSTDSGDIATGATAYSLKTSDD 1045

Query: 837  ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            A L  +N +TG++TL+   +  +       V  TD
Sbjct: 1046 AALFTINSSTGAVTLTANPDDEIRADYNFTVVATD 1080



 Score =  139 bits (336), Expect = 1e-30
 Identities = 127/497 (25%), Positives = 222/497 (44%), Gaps = 25/497 (5%)

Query: 378 DEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437
           DE  GT  V   A   DE+ R  + +TG +    F+I S  G  ++T A P D++ +  Y
Sbjct: 503 DENSGTHQVVYQAVTNDENAR--FSLTGDDA-SLFAINSSTGTVILT-ANP-DYESKADY 557

Query: 438 VLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497
             T+ A+D  G      V  +ITD +  AP   +A   +++ E++  G  V  V++TDS 
Sbjct: 558 NFTLVASDPAGNISEQSVTFDITDLDEVAPTITSASTASTIDENSGSGQVVYTVTSTDSS 617

Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG 557
                  +YSL +   ++A       F IN  TGA+T     D ET + Y  TV A D  
Sbjct: 618 DITTGATSYSLKA--GDDAAL-----FNINSSTGAVTLTADPDDETKADYNFTVLASDAA 670

Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617
             S      + + ++D++D  P          + E++  G  V  V +TD+D   +G   
Sbjct: 671 GNSREQA--ITLDIIDLDDVAPTITSASSATALDENSGAGQVVYTVTSTDSDDVSSGSTD 728

Query: 618 YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
           Y L   D +   F I+ ++G +  +   D E+ A ++   VA D      S+   + + I
Sbjct: 729 YSLKTGD-DAALFTINSSTGAVTLSADPDDETKADYNFTVVASDSAG--NSTEQAITLDI 785

Query: 678 EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL 737
            D+++  P   S  +   + ENS  G  +  + + D  +       YS+K GDD+  F++
Sbjct: 786 IDLDEVAPTITSTAIAAALDENSGAGQVVYTVTSTDSGDIATGATAYSLKIGDDAALFTI 845

Query: 738 ETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDF 797
            +  G    E+  + + D E+       V+ + S     +  + + +TD++D AP +   
Sbjct: 846 NSGTG----EVTLIANPDDETKADYNFTVVASDSAGNSTEQAITLDITDLDDVAPTITS- 900

Query: 798 QIIFNNYKDCFPVGPFG-RVPAYDA-DV-TDKLQYRILSGNNANLILLNETTGSMTLSPQ 854
            +      +   VG     V + D+ D+ T    Y + +G++A L  +N +TG++TL+  
Sbjct: 901 SVTATAIDENSGVGQVVYTVTSTDSGDIATGVTAYSLKAGDDAALFTINSSTGAVTLTAN 960

Query: 855 LNTNVPKLATMEVSVTD 871
            +       +  V  TD
Sbjct: 961 PDDETKADYSFTVVATD 977


>UniRef50_Q4S0C3 Cluster: Chromosome 2 SCAF14781, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 2
           SCAF14781, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 881

 Score =  209 bits (510), Expect = 1e-51
 Identities = 175/581 (30%), Positives = 268/581 (46%), Gaps = 38/581 (6%)

Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDG-GSPSRSNTTQLLI 245
           + ++  N      +  + G +S+   +D EQ+  RS R +I       +  +     + I
Sbjct: 59  FRLMQENNSSVIQMREVDGLLSVADVIDREQLCPRSLRCLITFDIVVRAKEKFQLIHVEI 118

Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
            ++D+ND+ PRF  +     + ENVP+G       A D D G N   +Y ++   +   V
Sbjct: 119 EVKDINDHPPRFPHNETHLEIVENVPLGSRFPLEIALDQDVGENYIQSYNISPSSHF-EV 177

Query: 306 DLPITIDP-RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
           ++    D  +   +    +LDRE +  Y + VTATDGG   RS +               
Sbjct: 178 EVRDQEDGLKFAELVLVRELDREVEDSYTIKVTATDGGVHARSGSMLVNIKVLDSNDNSP 237

Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTR--GR-FSITSQNG 419
            F      VEL ED P G  V+ + A D DE  +  + Y +  G +   GR F +    G
Sbjct: 238 SFEHSSLTVELDEDSPVGHRVLRVHAFDPDEGVNGEVTYALAAGFSPEVGRLFHVDPYTG 297

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYT-- 475
              +T+   +DF++ R Y L + A+D G  S   T  V I++ D N+ AP     P T  
Sbjct: 298 E--VTLKGLVDFERRRLYELVIKASDMGANSVPSTCKVHIDVVDVNDNAPEISIKPMTPG 355

Query: 476 ----ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
               AS+ E A   + V ++S +D D G N  +  SL   + +E   H   Q        
Sbjct: 356 SDGVASITEAAAADSFVALISTSDRDSGSNGYVRVSL---LGHE---HFSLQQAYGDSFM 409

Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
            ITT   LDRE +  Y LTV A D G P         + V D NDN P+F + LY  +++
Sbjct: 410 IITTT-ALDRERIPEYNLTVVAEDLGNPPFKTVRQYTVRVKDENDNPPLFSKTLYEVSVL 468

Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV-----IDPASGVIRTNKALD 646
           E+ + G+ V+ V A D DVG N ++ Y++   +   GS V     +D  SG + T ++ D
Sbjct: 469 ENNIPGSYVTTVVARDPDVGENAKVSYKVLDAEVPGGSPVSTYVSVDSHSGSLYTLRSFD 528

Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS-P----PVFESDCLTFYISENSP 701
            E++   DL   A D G+P  SST  + IK+ D ND+ P    PV ++D     +  N+P
Sbjct: 529 YETLQQIDLVIQAEDRGSPSLSSTSTIRIKVVDQNDNYPYFTFPVLQNDSADVPLPFNAP 588

Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
            G     + A D DEG N V+ + I  G D+N F ++   G
Sbjct: 589 AGYLALRVSAEDEDEGMNKVLSFQIFQG-DTNLFRVDKDSG 628



 Score =  204 bits (499), Expect = 2e-50
 Identities = 151/473 (31%), Positives = 236/473 (49%), Gaps = 35/473 (7%)

Query: 423 ITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
           + + + LD + E  Y + V+ATD G   RS + +V I + D+N+ +P FE++  T  + E
Sbjct: 191 LVLVRELDREVEDSYTIKVTATDGGVHARSGSMLVNIKVLDSNDNSPSFEHSSLTVELDE 250

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           D+P+G  VL V A D D G+N ++TY+L++  S E      + F ++P TG +T   L+D
Sbjct: 251 DSPVGHRVLRVHAFDPDEGVNGEVTYALAAGFSPEV----GRLFHVDPYTGEVTLKGLVD 306

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT------ANIMEDA 594
            E    Y L + A D G  S+  T  V I VVDVNDN P    +  T      A+I E A
Sbjct: 307 FERRRLYELVIKASDMGANSVPSTCKVHIDVVDVNDNAPEISIKPMTPGSDGVASITEAA 366

Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG---VIRTNKALDRESVA 651
              + V+ +  +D D G NG +   L   +     F +  A G   +I T  ALDRE + 
Sbjct: 367 AADSFVALISTSDRDSGSNGYVRVSLLGHEH----FSLQQAYGDSFMIITTTALDRERIP 422

Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711
            ++L  VA D G PP  +     ++++D ND+PP+F        + EN+  G+ +  + A
Sbjct: 423 EYNLTVVAEDLGNPPFKTVRQYTVRVKDENDNPPLFSKTLYEVSVLENNIPGSYVTTVVA 482

Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK--AELVTMVDLDYESPRKKYELVIRA 769
            DPD G NA V Y +   +      + T    D     L T+   DYE+  ++ +LVI+A
Sbjct: 483 RDPDVGENAKVSYKVLDAEVPGGSPVSTYVSVDSHSGSLYTLRSFDYET-LQQIDLVIQA 541

Query: 770 ---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC-FPV-GPFG----RVPAYD 820
               SP L +   + I V D NDN P    F ++ N+  D   P   P G    RV A D
Sbjct: 542 EDRGSPSLSSTSTIRIKVVDQNDNYPYF-TFPVLQNDSADVPLPFNAPAGYLALRVSAED 600

Query: 821 AD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            D  +   L ++I  G + NL  +++ +G + L   L+  +  +  +++SV+D
Sbjct: 601 EDEGMNKVLSFQIFQG-DTNLFRVDKDSGEIVLKQWLSAEIGDVLEIKISVSD 652



 Score =  187 bits (456), Expect = 3e-45
 Identities = 155/566 (27%), Positives = 247/566 (43%), Gaps = 25/566 (4%)

Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195
           + + + D ND+ P+F      + + E++ +     +    A D DVG N    Y I   +
Sbjct: 116 VEIEVKDINDHPPRFPHNETHLEIVENVPLGSRFPLEI--ALDQDVGENYIQSYNISPSS 173

Query: 196 ---TQMQFSIDSLS-GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251
               +++   D L   ++ LV+ LD E   SY + + A DGG  +RS +  + I + D N
Sbjct: 174 HFEVEVRDQEDGLKFAELVLVRELDREVEDSYTIKVTATDGGVHARSGSMLVNIKVLDSN 233

Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311
           DN+P F  S     + E+ P+G+ ++RV A+D DEGVN E+TY +    ++  V     +
Sbjct: 234 DNSPSFEHSSLTVELDEDSPVGHRVLRVHAFDPDEGVNGEVTYALA-AGFSPEVGRLFHV 292

Query: 312 DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA-----TXXXXXXXXXXXXXXF 366
           DP +G V   G +D E +  Y+L++ A+D G     +T                      
Sbjct: 293 DPYTGEVTLKGLVDFERRRLYELVIKASDMGANSVPSTCKVHIDVVDVNDNAPEISIKPM 352

Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG-LITV 425
            PG   V    +       V L +T   +     Y          FS+    G   +I  
Sbjct: 353 TPGSDGVASITEAAAADSFVALISTSDRDSGSNGYVRVSLLGHEHFSLQQAYGDSFMIIT 412

Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAMVQ--INITDANNYAPVFENAPYTASVFEDAP 483
              LD ++   Y LTV A D G      + Q  + + D N+  P+F    Y  SV E+  
Sbjct: 413 TTALDRERIPEYNLTVVAEDLGNPPFKTVRQYTVRVKDENDNPPLFSKTLYEVSVLENNI 472

Query: 484 IGTTVLVVSATDSDVGINAQITYS-LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
            G+ V  V A D DVG NA+++Y  L +E+   +         ++  +G++ T +  D E
Sbjct: 473 PGSYVTTVVARDPDVGENAKVSYKVLDAEVPGGSPV--STYVSVDSHSGSLYTLRSFDYE 530

Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME-----DALVG 597
           T+    L + A D G PSLS T+ + I VVD NDN P F   +   +  +     +A  G
Sbjct: 531 TLQQIDLVIQAEDRGSPSLSSTSTIRIKVVDQNDNYPYFTFPVLQNDSADVPLPFNAPAG 590

Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
               +V A D D G+N  + +++   D     F +D  SG I   + L  E     ++K 
Sbjct: 591 YLALRVSAEDEDEGMNKVLSFQIFQGD--TNLFRVDKDSGEIVLKQWLSAEIGDVLEIKI 648

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDS 683
              D G  P SS+  +   + D   S
Sbjct: 649 SVSDNGRSPLSSSATIRFLVSDTEPS 674



 Score =  175 bits (427), Expect = 1e-41
 Identities = 163/591 (27%), Positives = 254/591 (42%), Gaps = 58/591 (9%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           IH +I V D NDH P F   +    + E    G+      A DQD+G+N    Y I    
Sbjct: 114 IHVEIEVKDINDHPPRFPHNETHLEIVENVPLGSRFPLEIALDQDVGENYIQSYNI---- 169

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGA-LLTRASLDREKVARYTVLVKATDQASP 125
               +P             V+D  + DG   A L+    LDRE    YT+ V ATD    
Sbjct: 170 ----SPSS------HFEVEVRD--QEDGLKFAELVLVRELDREVEDSYTIKVTATDGG-- 215

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
           V  R S +  +++ ++D NDN P F   + TV +DED  V     + ++ A D D G N 
Sbjct: 216 VHAR-SGSMLVNIKVLDSNDNSPSFEHSSLTVELDEDSPVGHR--VLRVHAFDPDEGVNG 272

Query: 186 AIRYAIIGG---NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
            + YA+  G        F +D  +G+V+L   +D+E+ R Y LVI+A D G+ S  +T +
Sbjct: 273 EVTYALAAGFSPEVGRLFHVDPYTGEVTLKGLVDFERRRLYELVIKASDMGANSVPSTCK 332

Query: 243 LLINIRDVNDNAPRFYTSLFQ------ESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
           + I++ DVNDNAP               S++E       +  +   D D G N  +  ++
Sbjct: 333 VHIDVVDVNDNAPEISIKPMTPGSDGVASITEAAAADSFVALISTSDRDSGSNGYVRVSL 392

Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
              ++     L       S  + T+  LDRE   +Y L V A D G+PP           
Sbjct: 393 LGHEH---FSLQQAYGD-SFMIITTTALDRERIPEYNLTVVAEDLGNPPFKTVRQYTVRV 448

Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHY-----EITGGNTR 409
                    F    YEV + E+  PG+ V T+ A D D  E+ ++ Y     E+ GG+  
Sbjct: 449 KDENDNPPLFSKTLYEVSVLENNIPGSYVTTVVARDPDVGENAKVSYKVLDAEVPGGSPV 508

Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDAN-NYA 466
             +     +   L T+ +  D++  ++  L + A D G    S T+ ++I + D N NY 
Sbjct: 509 STYVSVDSHSGSLYTL-RSFDYETLQQIDLVIQAEDRGSPSLSSTSTIRIKVVDQNDNYP 567

Query: 467 ----PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522
               PV +N      +  +AP G   L VSA D D G+N  +++ +    +N        
Sbjct: 568 YFTFPVLQNDSADVPLPFNAPAGYLALRVSAEDEDEGMNKVLSFQIFQGDTN-------- 619

Query: 523 QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
            F ++  +G I   + L  E      + ++  D G   LS +  +   V D
Sbjct: 620 LFRVDKDSGEIVLKQWLSAEIGDVLEIKISVSDNGRSPLSSSATIRFLVSD 670



 Score =  142 bits (345), Expect = 9e-32
 Identities = 126/430 (29%), Positives = 195/430 (45%), Gaps = 26/430 (6%)

Query: 421 GLITVAQPLDFKQ----ERRYVLTVS-ATDSGGRSDTAMVQINITDANNYAPVFENAPYT 475
           GL++VA  +D +Q      R ++T      +  +     V+I + D N++ P F +    
Sbjct: 77  GLLSVADVIDREQLCPRSLRCLITFDIVVRAKEKFQLIHVEIEVKDINDHPPRFPHNETH 136

Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
             + E+ P+G+   +  A D DVG N   +Y++S   S+  V   DQ+  +  +   +  
Sbjct: 137 LEIVENVPLGSRFPLEIALDQDVGENYIQSYNISPS-SHFEVEVRDQEDGL--KFAELVL 193

Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
            + LDRE    Y + VTA DGGV + S +  V I V+D NDN P F+    T  + ED+ 
Sbjct: 194 VRELDREVEDSYTIKVTATDGGVHARSGSMLVNIKVLDSNDNSPSFEHSSLTVELDEDSP 253

Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGS--FVIDPASGVIRTNKALDRESVATH 653
           VG  V +V A D D G+NG + Y L      E    F +DP +G +     +D E    +
Sbjct: 254 VGHRVLRVHAFDPDEGVNGEVTYALAAGFSPEVGRLFHVDPYTGEVTLKGLVDFERRRLY 313

Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT------FYISENSPIGTTIG 707
           +L   A D G     ST  VHI + D+ND+ P      +T        I+E +   + + 
Sbjct: 314 ELVIKASDMGANSVPSTCKVHIDVVDVNDNAPEISIKPMTPGSDGVASITEAAAADSFVA 373

Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
            I   D D G N  V  S+ G +    FSL+   G D   ++T   LD E    +Y L +
Sbjct: 374 LISTSDRDSGSNGYVRVSLLGHE---HFSLQQAYG-DSFMIITTTALDRER-IPEYNLTV 428

Query: 768 RA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVT 824
            A    +PP     +  + V D NDN P+        +  ++  P      V A D DV 
Sbjct: 429 VAEDLGNPPFKTVRQYTVRVKDENDNPPLFSKTLYEVSVLENNIPGSYVTTVVARDPDVG 488

Query: 825 D--KLQYRIL 832
           +  K+ Y++L
Sbjct: 489 ENAKVSYKVL 498



 Score =  104 bits (249), Expect = 4e-20
 Identities = 72/254 (28%), Positives = 117/254 (46%), Gaps = 20/254 (7%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + V D ND+ P+F    YE SV E    G+ V T+ A D D+G+NA+V Y +        
Sbjct: 446 VRVKDENDNPPLFSKTLYEVSVLENNIPGSYVTTVVARDPDVGENAKVSYKVLDAEVPGG 505

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           +P             V     +D  SG+L T  S D E + +  ++++A D+ SP    L
Sbjct: 506 SP-------------VSTYVSVDSHSGSLYTLRSFDYETLQQIDLVIQAEDRGSP---SL 549

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTY---TVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
           SST+TI + ++D NDNYP F+       +  V    +     +  ++ A D D G N  +
Sbjct: 550 SSTSTIRIKVVDQNDNYPYFTFPVLQNDSADVPLPFNAPAGYLALRVSAEDEDEGMNKVL 609

Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            + I  G+T + F +D  SG++ L + L  E      + I   D G    S++  +   +
Sbjct: 610 SFQIFQGDTNL-FRVDKDSGEIVLKQWLSAEIGDVLEIKISVSDNGRSPLSSSATIRFLV 668

Query: 248 RDVNDNAPRFYTSL 261
            D   +A + +  L
Sbjct: 669 SDTEPSADQVFLVL 682


>UniRef50_UPI000069E7C3 Cluster: Protocadherin beta 11 precursor
           (PCDH-beta11).; n=9; Xenopus tropicalis|Rep:
           Protocadherin beta 11 precursor (PCDH-beta11). - Xenopus
           tropicalis
          Length = 795

 Score =  206 bits (504), Expect = 5e-51
 Identities = 163/564 (28%), Positives = 263/564 (46%), Gaps = 34/564 (6%)

Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194
           +I V I D NDN P F + +  + + E  S           A D D+G NS   Y +   
Sbjct: 119 SIKVEIQDINDNAPSFPKNSLKIVISE--SALPGVRFGLGYAQDPDLGINSVQSYGLSTN 176

Query: 195 NTQMQFSIDSLSG----DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
           +  +     S  G    ++ L K+LD EQ  S  L + A DGG P ++ TT + I + D 
Sbjct: 177 DYFILGERTSSDGSKYPELVLEKSLDREQQSSIELSLSASDGGRPMKTGTTLIRIVVYDA 236

Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310
           NDN P F    +Q ++ ENV   +S++++QA D DEG N ++TY+ T      N     +
Sbjct: 237 NDNHPVFSQDNYQVNIYENVANNFSVLQIQATDIDEGANGQITYSFT--HIPENALHIFS 294

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
           ID ++G +   G LD E   KY L V A DGG+       +                   
Sbjct: 295 IDSQTGQITKIGDLDYEVTKKYTLTVEAKDGGELVSHCKVSIQVIDANDNAPEIQI--NS 352

Query: 371 YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
           +   + ED PP T +  +   D D  E+  +  +I   N   +    +++   L+T+++ 
Sbjct: 353 FLGTVPEDSPPETVIAIIYVHDLDSGENGEVVCQIP-ENLPFQLITLTESYYKLVTLSR- 410

Query: 429 LDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGT 486
           +D ++   Y ++++A D G  S +++  +++ +TD N+  PVFE   Y   V E+   G 
Sbjct: 411 MDRERTSEYNISITAKDKGTPSLSSLKTIRVALTDVNDNIPVFEKTHYVTYVPENNQPGM 470

Query: 487 TVLVVSATDSDVGINAQITYS-LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
           ++L V+A D D+  N  ITYS +S+ I N  ++ H     IN  TG I      D E + 
Sbjct: 471 SILHVNALDFDINDNGFITYSVISTAIQNIPISSH---VSINSATGVIYALHAFDYEQIR 527

Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV--------- 596
            +   V A D G PSLS  + + + ++D NDN P   + LY ++  E   +         
Sbjct: 528 EFQFQVMATDNGSPSLSSNSTIRVCIIDKNDNAP---EILYPSSDTEGTALYEFIPHSSD 584

Query: 597 -GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655
            G  V++V A DAD G N  + Y L  + +E   F I  ++G IR  +       +   +
Sbjct: 585 RGYLVTKVIAVDADSGHNAWLSYHL-LQAQEPSVFTIGQSTGEIRLARGFQETDSSRQKV 643

Query: 656 KAVAIDGGTPPQSSTVIVHIKIED 679
             +  D G P  S+TV +++ I +
Sbjct: 644 VVMVKDNGEPTLSATVTLNLIIAE 667



 Score =  174 bits (423), Expect = 3e-41
 Identities = 155/582 (26%), Positives = 251/582 (43%), Gaps = 53/582 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ + D ND++P F     +  + E A  G       A D D+G N+   Y +       
Sbjct: 121 KVEIQDINDNAPSFPKNSLKIVISESALPGVRFGLGYAQDPDLGINSVQSYGLSTNDYFI 180

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
           L    +                 DG +   L+   SLDRE+ +   + + A+D   P+  
Sbjct: 181 LGERTSS----------------DGSKYPELVLEKSLDREQQSSIELSLSASDGGRPMK- 223

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             + T  I + + D NDN+P FS+  Y V++ E  +V +N  + +I+ATD D GAN  I 
Sbjct: 224 --TGTTLIRIVVYDANDNHPVFSQDNYQVNIYE--NVANNFSVLQIQATDIDEGANGQIT 279

Query: 189 YAI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           Y+   I  N    FSIDS +G ++ +  LDYE  + Y L + A+DGG     +  ++ I 
Sbjct: 280 YSFTHIPENALHIFSIDSQTGQITKIGDLDYEVTKKYTLTVEAKDGG--ELVSHCKVSIQ 337

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
           + D NDNAP    + F  +V E+ P    I  +  +D D G N E+   + +     N+ 
Sbjct: 338 VIDANDNAPEIQINSFLGTVPEDSPPETVIAIIYVHDLDSGENGEVVCQIPE-----NLP 392

Query: 307 LP-ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
              IT+      + T  ++DRE  ++Y + +TA D G P  S+  T              
Sbjct: 393 FQLITLTESYYKLVTLSRMDRERTSEYNISITAKDKGTPSLSSLKTIRVALTDVNDNIPV 452

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDAD-EDNR-LHYEITG---GNTRGRFSITSQNGR 420
           F    Y   + E+  PG  ++ + A D D  DN  + Y +      N      ++  +  
Sbjct: 453 FEKTHYVTYVPENNQPGMSILHVNALDFDINDNGFITYSVISTAIQNIPISSHVSINSAT 512

Query: 421 GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVF---ENAPYT 475
           G+I      D++Q R +   V ATD+G    S  + +++ I D N+ AP      +    
Sbjct: 513 GVIYALHAFDYEQIREFQFQVMATDNGSPSLSSNSTIRVCIIDKNDNAPEILYPSSDTEG 572

Query: 476 ASVFEDAP----IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
            +++E  P     G  V  V A D+D G NA ++Y L         A     F I   TG
Sbjct: 573 TALYEFIPHSSDRGYLVTKVIAVDADSGHNAWLSYHLLQ-------AQEPSVFTIGQSTG 625

Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
            I   +       S   + V  +D G P+LS T  + + + +
Sbjct: 626 EIRLARGFQETDSSRQKVVVMVKDNGEPTLSATVTLNLIIAE 667



 Score =  166 bits (404), Expect = 7e-39
 Identities = 116/376 (30%), Positives = 183/376 (48%), Gaps = 15/376 (3%)

Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480
           + + + LD +Q+    L++SA+D G   ++ T +++I + DAN+  PVF    Y  +++E
Sbjct: 195 LVLEKSLDREQQSSIELSLSASDGGRPMKTGTTLIRIVVYDANDNHPVFSQDNYQVNIYE 254

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           +     +VL + ATD D G N QITYS +    N   A H   F I+ QTG IT    LD
Sbjct: 255 NVANNFSVLQIQATDIDEGANGQITYSFTHIPEN---ALHI--FSIDSQTGQITKIGDLD 309

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
            E    Y LTV A+DGG   L     V I V+D NDN P  +   +   + ED+   T +
Sbjct: 310 YEVTKKYTLTVEAKDGG--ELVSHCKVSIQVIDANDNAPEIQINSFLGTVPEDSPPETVI 367

Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
           + +   D D G NG +  ++ P++       +  +   + T   +DRE  + +++   A 
Sbjct: 368 AIIYVHDLDSGENGEVVCQI-PENLPFQLITLTESYYKLVTLSRMDRERTSEYNISITAK 426

Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
           D GTP  SS   + + + D+ND+ PVFE      Y+ EN+  G +I  + A D D   N 
Sbjct: 427 DKGTPSLSSLKTIRVALTDVNDNIPVFEKTHYVTYVPENNQPGMSILHVNALDFDINDNG 486

Query: 721 VVHYSIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776
            + YS+      N   S      S    +  +   DYE  R +++  + A    SP L +
Sbjct: 487 FITYSVISTAIQNIPISSHVSINSATGVIYALHAFDYEQIR-EFQFQVMATDNGSPSLSS 545

Query: 777 DVRVEILVTDVNDNAP 792
           +  + + + D NDNAP
Sbjct: 546 NSTIRVCIIDKNDNAP 561



 Score =  145 bits (351), Expect = 2e-32
 Identities = 126/404 (31%), Positives = 182/404 (45%), Gaps = 21/404 (5%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           +++ I D N+ AP F        + E A  G    +  A D D+GIN+  +Y LS+   N
Sbjct: 120 IKVEIQDINDNAPSFPKNSLKIVISESALPGVRFGLGYAQDPDLGINSVQSYGLST---N 176

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
           +     ++      +   +   K LDRE  S   L+++A DGG P  + TT + I V D 
Sbjct: 177 DYFILGERTSSDGSKYPELVLEKSLDREQQSSIELSLSASDGGRPMKTGTTLIRIVVYDA 236

Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP-KDREEGSFVID 633
           NDN PVF Q  Y  NI E+     SV Q+ ATD D G NG+I Y      +     F ID
Sbjct: 237 NDNHPVFSQDNYQVNIYENVANNFSVLQIQATDIDEGANGQITYSFTHIPENALHIFSID 296

Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693
             +G I     LD E    + L   A DGG     S   V I++ D ND+ P  + +   
Sbjct: 297 SQTGQITKIGDLDYEVTKKYTLTVEAKDGGE--LVSHCKVSIQVIDANDNAPEIQINSFL 354

Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753
             + E+SP  T I  I  HD D G N  V   I    ++  F L T   S   +LVT+  
Sbjct: 355 GTVPEDSPPETVIAIIYVHDLDSGENGEVVCQIP---ENLPFQLITLTES-YYKLVTLSR 410

Query: 754 LDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV 810
           +D E    +Y + I A    +P L +   + + +TDVNDN PV +    +    ++  P 
Sbjct: 411 MDRERT-SEYNISITAKDKGTPSLSSLKTIRVALTDVNDNIPVFEKTHYVTYVPENNQPG 469

Query: 811 GPFGRVPAYDADVTDK--LQYRILSGNNANL-----ILLNETTG 847
                V A D D+ D   + Y ++S    N+     + +N  TG
Sbjct: 470 MSILHVNALDFDINDNGFITYSVISTAIQNIPISSHVSINSATG 513



 Score =  114 bits (274), Expect = 4e-23
 Identities = 88/290 (30%), Positives = 138/290 (47%), Gaps = 14/290 (4%)

Query: 512 ISNEAVAHHDQ-QFV-INPQTGAITTNKLLDRETMSGY-LLTVTARDGGVPSLSDTTDVE 568
           + N  +A HD+ Q+V +N + G +   + +DRE + G     +      + +      ++
Sbjct: 62  LRNLHIASHDKKQYVNVNLENGDLVITEKIDREALCGTEQQCILNLKAMIENPLQIFSIK 121

Query: 569 ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE- 627
           + + D+NDN P F +      I E AL G       A D D+G+N    Y L   D    
Sbjct: 122 VEIQDINDNAPSFPKNSLKIVISESALPGVRFGLGYAQDPDLGINSVQSYGLSTNDYFIL 181

Query: 628 GSFVIDPASGV--IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685
           G       S    +   K+LDRE  ++ +L   A DGG P ++ T ++ I + D ND+ P
Sbjct: 182 GERTSSDGSKYPELVLEKSLDREQQSSIELSLSASDGGRPMKTGTTLIRIVVYDANDNHP 241

Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS--NSFSLETRQGS 743
           VF  D     I EN     ++ +I+A D DEG N  + YS     ++  + FS++++ G 
Sbjct: 242 VFSQDNYQVNIYENVANNFSVLQIQATDIDEGANGQITYSFTHIPENALHIFSIDSQTG- 300

Query: 744 DKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAP 792
              ++  + DLDYE   KKY L + A     L +  +V I V D NDNAP
Sbjct: 301 ---QITKIGDLDYE-VTKKYTLTVEAKDGGELVSHCKVSIQVIDANDNAP 346



 Score = 74.9 bits (176), Expect = 3e-11
 Identities = 63/223 (28%), Positives = 102/223 (45%), Gaps = 11/223 (4%)

Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732
           + ++I+DIND+ P F  + L   ISE++  G   G   A DPD G N+V  Y +   D  
Sbjct: 120 IKVEIQDINDNAPSFPKNSLKIVISESALPGVRFGLGYAQDPDLGINSVQSYGLSTNDYF 179

Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVND 789
                 +  GS   ELV    LD E  +   EL + A+    P       + I+V D ND
Sbjct: 180 ILGERTSSDGSKYPELVLEKSLDREQ-QSSIELSLSASDGGRPMKTGTTLIRIVVYDAND 238

Query: 790 NAPVMK--DFQI-IFNNYKDCFPVGPFGRVPAYDADVTDKLQYRI--LSGNNANLILLNE 844
           N PV    ++Q+ I+ N  + F V    +    D     ++ Y    +  N  ++  ++ 
Sbjct: 239 NHPVFSQDNYQVNIYENVANNFSVLQI-QATDIDEGANGQITYSFTHIPENALHIFSIDS 297

Query: 845 TTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887
            TG +T    L+  V K  T+ V   DG  E+ +  ++S+++I
Sbjct: 298 QTGQITKIGDLDYEVTKKYTLTVEAKDG-GELVSHCKVSIQVI 339


>UniRef50_Q4S489 Cluster: Chromosome 1 SCAF14742, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 1 SCAF14742, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 891

 Score =  206 bits (502), Expect = 9e-51
 Identities = 158/538 (29%), Positives = 252/538 (46%), Gaps = 38/538 (7%)

Query: 279 VQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA 338
           V+A DAD G+N E+ Y+      T  V   + ID  +G +Y  GQ+DRE +   +  V A
Sbjct: 333 VRANDADTGINGEIDYSFHQASDT--VQRLLRIDRFTGIIYVKGQVDREEENFLKFFVAA 390

Query: 339 TDGGDPPRSATATXXXXXXXXXXXXXXF-MPGQYEV-------ELAEDEPPGTPVVTLTA 390
            D G   +++                   + G   V        ++ED P GTPV  +  
Sbjct: 391 RDRGPNSKTSKVLVTITVKDQNDNSPSIEIRGIGLVTHRNGVANISEDMPVGTPVALVQV 450

Query: 391 TDADE-DNRLHYEITGGNT--RGRFSITSQNGRG---LITVAQPLDFKQERRYVLTVSAT 444
           +D DE +N +   +  G+   + R +  S N R     +     LD+++ + Y + + A 
Sbjct: 451 SDRDEGENAVVTCVVAGDVPFQLRPASESSNDRKRKYFLQTTTLLDYERVKDYRIEIVAV 510

Query: 445 DSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502
           DSG    S T  +++ +TD N+  P+F          E    G  VL V ATD+D G NA
Sbjct: 511 DSGNPALSSTNFLKVQVTDVNDNIPIFSPPLLKVDFAEGNYPGDKVLDVLATDADSGSNA 570

Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
           ++TYS+S   + E        F ++  +G +    +L+RE    Y   V A D GVP  +
Sbjct: 571 ELTYSISEPAALEL-------FEVDANSGEVRVRAVLNREQREHYRFHVAAADKGVPGKT 623

Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP 622
            T  VEI+V+DVNDN+P F    Y+ ++ E+      V  V  TD D G N R+   ++P
Sbjct: 624 GTATVEITVLDVNDNDPKFMLDDYSFSVNENMAPLNPVGVVTVTDGDKGENARVTLLVEP 683

Query: 623 KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND 682
              + G FVI   +G I ++ + DRE  +T+  +  A+D G PP++S V V I + D ND
Sbjct: 684 ---DNGKFVIQNGTGTILSSISFDREKESTYTFRLKAVDAGDPPRTSYVAVTINVLDEND 740

Query: 683 SPP-VFESDCLTF-YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR 740
           + P V +    TF ++  ++P  T +  + A D D G NA + Y++ GG+    F +   
Sbjct: 741 NAPYVTKPSNSTFTHLLPDTPPDTRVAVVEAEDIDSGLNAELVYTLAGGNPFGLFRIAPG 800

Query: 741 QGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMK 795
            G      +T+      S R  + LV+R +    PP      V + V +   N  +++
Sbjct: 801 SGE-----ITLAQKLAGSHRGLHRLVVRVSDRGKPPRHTTALVHVFVNETKYNTSLIE 853



 Score =  193 bits (470), Expect = 7e-47
 Identities = 200/757 (26%), Positives = 319/757 (42%), Gaps = 55/757 (7%)

Query: 138 VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQ 197
           + ++D NDN PQFS    T+S+ E+  V    + A   ATD D GAN    Y +  G   
Sbjct: 102 IEVLDINDNTPQFSSPILTLSIPENTQV--GALFAIPMATDRDAGANGVAEYTLTAGPDA 159

Query: 198 MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP-R 256
            Q          SL   +D ++ +  +LV+     G+  R       +NIR V+   P R
Sbjct: 160 DQL--------FSLQVAVDSDE-KVPQLVVM----GNLDREKKDSYDLNIRVVDGGRPAR 206

Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316
             ++L + SV++         R   Y+A+   N+   Y++       +   P+     S 
Sbjct: 207 ASSALLRVSVTDQNDNQPKFERSH-YEAELTENSPQGYSVLQPRPPAS---PVCSGSASW 262

Query: 317 WVYTSGQLDRETQAKYQLLVTATDGGDPPR------SATATXXXXXXXXXXXXXXFMPGQ 370
           +++ S ++  + Q+ +   ++   G  PPR       A                    G 
Sbjct: 263 FLFLS-RVSPDAQSGF---ISQPGGTSPPRWLLVNQRANTGWKAVALGAQPTGSALQDGW 318

Query: 371 YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
             V         + V    A DAD   +  + Y     +   +  +      G+I V   
Sbjct: 319 ISVSNRRRRLVASEV---RANDADTGINGEIDYSFHQASDTVQRLLRIDRFTGIIYVKGQ 375

Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFE--------NAPYTASV 478
           +D ++E      V+A D G  S T+ V + IT  D N+ +P  E        +    A++
Sbjct: 376 VDREEENFLKFFVAARDRGPNSKTSKVLVTITVKDQNDNSPSIEIRGIGLVTHRNGVANI 435

Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
            ED P+GT V +V  +D D G NA +T  ++ ++  + +    +      +   + T  L
Sbjct: 436 SEDMPVGTPVALVQVSDRDEGENAVVTCVVAGDVPFQ-LRPASESSNDRKRKYFLQTTTL 494

Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
           LD E +  Y + + A D G P+LS T  +++ V DVNDN P+F   L   +  E    G 
Sbjct: 495 LDYERVKDYRIEIVAVDSGNPALSSTNFLKVQVTDVNDNIPIFSPPLLKVDFAEGNYPGD 554

Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
            V  V ATDAD G N  + Y +      E  F +D  SG +R    L+RE    +     
Sbjct: 555 KVLDVLATDADSGSNAELTYSISEPAALE-LFEVDANSGEVRVRAVLNREQREHYRFHVA 613

Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
           A D G P ++ T  V I + D+ND+ P F  D  +F ++EN      +G +   D D+G 
Sbjct: 614 AADKGVPGKTGTATVEITVLDVNDNDPKFMLDDYSFSVNENMAPLNPVGVVTVTDGDKGE 673

Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDV 778
           NA V   ++   D+  F ++   G+  + +    D + ES        + A  PP  + V
Sbjct: 674 NARVTLLVE--PDNGKFVIQNGTGTILSSI--SFDREKESTYTFRLKAVDAGDPPRTSYV 729

Query: 779 RVEILVTDVNDNAP-VMKDFQIIFNNY-KDCFPVGPFGRVPAYDAD--VTDKLQYRILSG 834
            V I V D NDNAP V K     F +   D  P      V A D D  +  +L Y +  G
Sbjct: 730 AVTINVLDENDNAPYVTKPSNSTFTHLLPDTPPDTRVAVVEAEDIDSGLNAELVYTLAGG 789

Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
           N   L  +   +G +TL+ +L  +   L  + V V+D
Sbjct: 790 NPFGLFRIAPGSGEITLAQKLAGSHRGLHRLVVRVSD 826



 Score =  193 bits (470), Expect = 7e-47
 Identities = 158/538 (29%), Positives = 246/538 (45%), Gaps = 30/538 (5%)

Query: 170 VIAKIKATDADVGANSAIRYAIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVI 227
           V ++++A DAD G N  I Y+    +  +Q    ID  +G + +   +D E+    +  +
Sbjct: 329 VASEVRANDADTGINGEIDYSFHQASDTVQRLLRIDRFTGIIYVKGQVDREEENFLKFFV 388

Query: 228 RAQDGGSPSRSNTTQLLINIRDVNDNAPRFY---TSLFQE-----SVSENVPIGYSIVRV 279
            A+D G  S+++   + I ++D NDN+P        L        ++SE++P+G  +  V
Sbjct: 389 AARDRGPNSKTSKVLVTITVKDQNDNSPSIEIRGIGLVTHRNGVANISEDMPVGTPVALV 448

Query: 280 QAYDADEGVNAELTYTMT-DKDYTGNVDLPITID-PRSGWVYTSGQLDRETQAKYQLLVT 337
           Q  D DEG NA +T  +  D  +        + D  R  ++ T+  LD E    Y++ + 
Sbjct: 449 QVSDRDEGENAVVTCVVAGDVPFQLRPASESSNDRKRKYFLQTTTLLDYERVKDYRIEIV 508

Query: 338 ATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN 397
           A D G+P  S+T                F P   +V+ AE   PG  V+ + ATDAD  +
Sbjct: 509 AVDSGNPALSSTNFLKVQVTDVNDNIPIFSPPLLKVDFAEGNYPGDKVLDVLATDADSGS 568

Query: 398 --RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTA 453
              L Y I+       F + + +G   + V   L+ +Q   Y   V+A D G  G++ TA
Sbjct: 569 NAELTYSISEPAALELFEVDANSGE--VRVRAVLNREQREHYRFHVAAADKGVPGKTGTA 626

Query: 454 MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513
            V+I + D N+  P F    Y+ SV E+      V VV+ TD D G NA++T  +  +  
Sbjct: 627 TVEITVLDVNDNDPKFMLDDYSFSVNENMAPLNPVGVVTVTDGDKGENARVTLLVEPD-- 684

Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
                  + +FVI   TG I ++   DRE  S Y   + A D G P  +    V I+V+D
Sbjct: 685 -------NGKFVIQNGTGTILSSISFDREKESTYTFRLKAVDAGDPPRTSYVAVTINVLD 737

Query: 574 VNDNEP-VFKQQLYT-ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631
            NDN P V K    T  +++ D    T V+ V A D D GLN  + Y L       G F 
Sbjct: 738 ENDNAPYVTKPSNSTFTHLLPDTPPDTRVAVVEAEDIDSGLNAELVYTL-AGGNPFGLFR 796

Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES 689
           I P SG I   + L       H L     D G PP+ +T +VH+ + +   +  + E+
Sbjct: 797 IAPGSGEITLAQKLAGSHRGLHRLVVRVSDRGKPPRHTTALVHVFVNETKYNTSLIEA 854



 Score =  186 bits (453), Expect = 8e-45
 Identities = 167/567 (29%), Positives = 251/567 (44%), Gaps = 61/567 (10%)

Query: 45  LKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS 104
           ++A D D G N E++Y+    + DT                VQ + RID  +G +  +  
Sbjct: 333 VRANDADTGINGEIDYSFHQAS-DT----------------VQRLLRIDRFTGIIYVKGQ 375

Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQF--------SEKTYT 156
           +DRE+       V A D+  P S   +S   + + + D NDN P          + +   
Sbjct: 376 VDREEENFLKFFVAARDR-GPNSK--TSKVLVTITVKDQNDNSPSIEIRGIGLVTHRNGV 432

Query: 157 VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD-------V 209
            ++ ED+ V   PV A ++ +D D G N+ +   ++ G+   Q    S S +       +
Sbjct: 433 ANISEDMPV-GTPV-ALVQVSDRDEGENAVVT-CVVAGDVPFQLRPASESSNDRKRKYFL 489

Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269
                LDYE+V+ YR+ I A D G+P+ S+T  L + + DVNDN P F   L +   +E 
Sbjct: 490 QTTTLLDYERVKDYRIEIVAVDSGNPALSSTNFLKVQVTDVNDNIPIFSPPLLKVDFAEG 549

Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329
              G  ++ V A DAD G NAELTY++++      ++L   +D  SG V     L+RE +
Sbjct: 550 NYPGDKVLDVLATDADSGSNAELTYSISE---PAALEL-FEVDANSGEVRVRAVLNREQR 605

Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389
             Y+  V A D G P ++ TAT              FM   Y   + E+  P  PV  +T
Sbjct: 606 EHYRFHVAAADKGVPGKTGTATVEITVLDVNDNDPKFMLDDYSFSVNENMAPLNPVGVVT 665

Query: 390 ATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG- 448
            TD D+       +      G+F I  QNG G I  +   D ++E  Y   + A D+G  
Sbjct: 666 VTDGDKGENARVTLLVEPDNGKFVI--QNGTGTILSSISFDREKESTYTFRLKAVDAGDP 723

Query: 449 -RSDTAMVQINITDANNYAPVF---ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504
            R+    V IN+ D N+ AP      N+ +T  +  D P  T V VV A D D G+NA++
Sbjct: 724 PRTSYVAVTINVLDENDNAPYVTKPSNSTFT-HLLPDTPPDTRVAVVEAEDIDSGLNAEL 782

Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT 564
            Y+L       A  +    F I P +G IT  + L       + L V   D G P    T
Sbjct: 783 VYTL-------AGGNPFGLFRIAPGSGEITLAQKLAGSHRGLHRLVVRVSDRGKPPRHTT 835

Query: 565 TDVEISVVDVNDN----EPVFKQQLYT 587
             V + V +   N    E +    LYT
Sbjct: 836 ALVHVFVNETKYNTSLIEALVGHSLYT 862



 Score =  144 bits (348), Expect = 4e-32
 Identities = 108/344 (31%), Positives = 166/344 (48%), Gaps = 34/344 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ V D ND+ P+F     +    EG   G  VL + ATD D G NAE+ Y+I       
Sbjct: 524 KVQVTDVNDNIPIFSPPLLKVDFAEGNYPGDKVLDVLATDADSGSNAELTYSIS------ 577

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
              E A            ++F +D  SG +  RA L+RE+   Y   V A D+  P    
Sbjct: 578 ---EPAAL----------ELFEVDANSGEVRVRAVLNREQREHYRFHVAAADKGVPGK-- 622

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            + TAT+ + ++D NDN P+F    Y+ SV+E+++   NPV   +  TD D G N+ +  
Sbjct: 623 -TGTATVEITVLDVNDNDPKFMLDDYSFSVNENMAPL-NPV-GVVTVTDGDKGENARVTL 679

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            +   N   +F I + +G +    + D E+  +Y   ++A D G P R++   + IN+ D
Sbjct: 680 LVEPDNG--KFVIQNGTGTILSSISFDREKESTYTFRLKAVDAGDPPRTSYVAVTINVLD 737

Query: 250 VNDNAP---RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            NDNAP   +   S F   + +  P    +  V+A D D G+NAEL YT+      GN  
Sbjct: 738 ENDNAPYVTKPSNSTFTHLLPDTPP-DTRVAVVEAEDIDSGLNAELVYTLAG----GNPF 792

Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350
               I P SG +  + +L    +  ++L+V  +D G PPR  TA
Sbjct: 793 GLFRIAPGSGEITLAQKLAGSHRGLHRLVVRVSDRGKPPRHTTA 836



 Score = 79.0 bits (186), Expect = 2e-12
 Identities = 53/179 (29%), Positives = 84/179 (46%), Gaps = 10/179 (5%)

Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
           N L   +    + +++T    G+ S     +  I V+D+NDN P F   + T +I E+  
Sbjct: 69  NPLAGDKCFLEFEVSITDMVKGLGSGPRLIEGRIEVLDINDNTPQFSSPILTLSIPENTQ 128

Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG--------VIRTNKALDR 647
           VG   +   ATD D G NG   Y L      +  F +  A          V+  N  LDR
Sbjct: 129 VGALFAIPMATDRDAGANGVAEYTLTAGPDADQLFSLQVAVDSDEKVPQLVVMGN--LDR 186

Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706
           E   ++DL    +DGG P ++S+ ++ + + D ND+ P FE       ++ENSP G ++
Sbjct: 187 EKKDSYDLNIRVVDGGRPARASSALLRVSVTDQNDNQPKFERSHYEAELTENSPQGYSV 245



 Score = 73.7 bits (173), Expect = 7e-11
 Identities = 42/147 (28%), Positives = 70/147 (47%)

Query: 456 QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515
           +I + D N+  P F +   T S+ E+  +G    +  ATD D G N    Y+L++    +
Sbjct: 101 RIEVLDINDNTPQFSSPILTLSIPENTQVGALFAIPMATDRDAGANGVAEYTLTAGPDAD 160

Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575
            +         + +   +     LDRE    Y L +   DGG P+ + +  + +SV D N
Sbjct: 161 QLFSLQVAVDSDEKVPQLVVMGNLDREKKDSYDLNIRVVDGGRPARASSALLRVSVTDQN 220

Query: 576 DNEPVFKQQLYTANIMEDALVGTSVSQ 602
           DN+P F++  Y A + E++  G SV Q
Sbjct: 221 DNQPKFERSHYEAELTENSPQGYSVLQ 247



 Score = 66.5 bits (155), Expect = 1e-08
 Identities = 47/161 (29%), Positives = 69/161 (42%), Gaps = 15/161 (9%)

Query: 2   SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
           S P  I  +I VLD ND++P F       S+ E    G       ATD+D G N   EYT
Sbjct: 93  SGPRLIEGRIEVLDINDNTPQFSSPILTLSIPENTQVGALFAIPMATDRDAGANGVAEYT 152

Query: 62  IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121
           +      T  P+            +Q     D +   L+   +LDREK   Y + ++  D
Sbjct: 153 L------TAGPD------ADQLFSLQVAVDSDEKVPQLVVMGNLDREKKDSYDLNIRVVD 200

Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162
              P     +S+A + V++ D NDN P+F    Y   + E+
Sbjct: 201 GGRPAR---ASSALLRVSVTDQNDNQPKFERSHYEAELTEN 238


>UniRef50_Q9Y5H0 Cluster: Protocadherin gamma A3 precursor; n=173;
           Mammalia|Rep: Protocadherin gamma A3 precursor - Homo
           sapiens (Human)
          Length = 932

 Score =  204 bits (499), Expect = 2e-50
 Identities = 166/611 (27%), Positives = 275/611 (45%), Gaps = 32/611 (5%)

Query: 194 GNTQMQFSIDSLSGDVSLVKTLDYEQV-RSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252
           G TQ+ FS++  SG +   + +D E++     L +   +     +    ++ I I+D+ND
Sbjct: 70  GRTQL-FSLNPQSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDIND 128

Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312
           NAP F T   +  + E    G       A+D D G+N+   Y ++  DY       ++  
Sbjct: 129 NAPNFPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEG 188

Query: 313 PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE 372
            +   +     LDRE +  +QL++ A+DGGDP  S                  F   +Y 
Sbjct: 189 AKYPELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYR 248

Query: 373 VELAEDEPPGTPVVTLTATDADE--DNRLHYEITG--GNTRGRFSITSQNGRGLITVAQP 428
           V + E+ P GT ++T+ ATD DE  + ++ Y +    G     F + S +G   +++ + 
Sbjct: 249 VSVWENVPVGTRLLTVNATDPDEGFNAQVSYILDKMPGKIAEIFHLNSVSGE--VSILKS 306

Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
           LD++    Y + + A D  G    A + + + D N+ AP       T+SV E+  +G  +
Sbjct: 307 LDYEDAMFYEIKIEAQDGPGLLSRAKILVTVLDVNDNAPEITITSLTSSVPEEGTVGREI 366

Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
            ++   D D G N Q+   +   +  +     DQ +        + T   LDRE +S Y 
Sbjct: 367 ALIDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYY-------RLVTATSLDREQISEYN 419

Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
           +++ A DGG P LS  T + + V+D+NDN P F    Y+A I E+   G S+  V A D 
Sbjct: 420 ISLRASDGGSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDP 479

Query: 609 DVGLNGRIHYELDPKDREEG----SFV-IDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
           D   N RI Y L  +D  +G    SFV I+  +GV+   ++ D E      L   A D G
Sbjct: 480 DSNNNARITYALT-EDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSG 538

Query: 664 TPPQSSTVIVHIKIEDINDSPP-----VFESDCLTFY--ISENSPIGTTIGEIRAHDPDE 716
            PP SS V +++ + D ND+ P        +D  T       ++  G  + ++ A D D 
Sbjct: 539 NPPLSSNVSLNLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDS 598

Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR-AASPPLW 775
           G NA + Y +    +   FS+    G  +        LD ++ ++   + I+    PPL 
Sbjct: 599 GQNAWLSYRLLKASEPGLFSVGLHTGEVRTARAL---LDRDALKQSLVVAIQDHGQPPLS 655

Query: 776 NDVRVEILVTD 786
             V + + V D
Sbjct: 656 ATVTLIVAVAD 666



 Score =  201 bits (490), Expect = 3e-49
 Identities = 176/608 (28%), Positives = 275/608 (45%), Gaps = 32/608 (5%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           +F ++ +SG+L+T   +DRE++     L         V D+L     + + I D NDN P
Sbjct: 74  LFSLNPQSGSLVTAERIDREELCAQIPLCLVKINIL-VEDKLK-IFEVEIEIKDINDNAP 131

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG- 207
            F  +   + + E ++V       K  A D DVG NS   Y +   N     +++S+S  
Sbjct: 132 NFPTEELEIKIGE-LTVPGTRFPIKT-AFDPDVGINSLQNYKL-SPNDYFSLAVNSVSEG 188

Query: 208 ----DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263
               ++ L + LD E+   ++LV+ A DGG P  S    + + + D NDN P F    ++
Sbjct: 189 AKYPELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYR 248

Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323
            SV ENVP+G  ++ V A D DEG NA+++Y + DK   G +     ++  SG V     
Sbjct: 249 VSVWENVPVGTRLLTVNATDPDEGFNAQVSYIL-DK-MPGKIAEIFHLNSVSGEVSILKS 306

Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383
           LD E    Y++ + A DG  P   + A                        + E+   G 
Sbjct: 307 LDYEDAMFYEIKIEAQDG--PGLLSRAKILVTVLDVNDNAPEITITSLTSSVPEEGTVGR 364

Query: 384 PVVTLTATDADEDNRLHYEI-TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
            +  +   D D       E+   GN   +   +      L+T A  LD +Q   Y +++ 
Sbjct: 365 EIALIDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVT-ATSLDREQISEYNISLR 423

Query: 443 ATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
           A+D G    S    + +++ D N+  P F +  Y+A + E+ P G ++  V+A D D   
Sbjct: 424 ASDGGSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNN 483

Query: 501 NAQITYSLSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
           NA+ITY+L+ +    A       FV IN  TG +   +  D E      L VTA D G P
Sbjct: 484 NARITYALTEDTLQGAPL---SSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNP 540

Query: 560 SLSDTTDVEISVVDVNDNEP-VFKQQLYTAN------IMEDALVGTSVSQVGATDADVGL 612
            LS    + + V+D NDN P +    L T            A  G  V++V A D D G 
Sbjct: 541 PLSSNVSLNLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQ 600

Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKA-LDRESVATHDLKAVAIDGGTPPQSSTV 671
           N  + Y L  K  E G F +   +G +RT +A LDR+++    + A+  D G PP S+TV
Sbjct: 601 NAWLSYRL-LKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAIQ-DHGQPPLSATV 658

Query: 672 IVHIKIED 679
            + + + D
Sbjct: 659 TLIVAVAD 666



 Score =  188 bits (459), Expect = 1e-45
 Identities = 141/493 (28%), Positives = 231/493 (46%), Gaps = 18/493 (3%)

Query: 310 TIDPRSGWVYTSGQLDRETQ-AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
           +++P+SG + T+ ++DRE   A+  L +   +     +                   F  
Sbjct: 76  SLNPQSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDINDNAPNFPT 135

Query: 369 GQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQNGRGL---IT 424
            + E+++ E   PGT     TA D D   N L       N     ++ S +       + 
Sbjct: 136 EELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEGAKYPELV 195

Query: 425 VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
           + + LD +++  + L + A+D G    S    +Q+ + DAN+  P+F    Y  SV+E+ 
Sbjct: 196 LERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRVSVWENV 255

Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
           P+GT +L V+ATD D G NAQ++Y L       A   H     +N  +G ++  K LD E
Sbjct: 256 PVGTRLLTVNATDPDEGFNAQVSYILDKMPGKIAEIFH-----LNSVSGEVSILKSLDYE 310

Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
               Y + + A+DG  P L     + ++V+DVNDN P       T+++ E+  VG  ++ 
Sbjct: 311 DAMFYEIKIEAQDG--PGLLSRAKILVTVLDVNDNAPEITITSLTSSVPEEGTVGREIAL 368

Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
           +   D D G NG++   +      +    ID    ++ T  +LDRE ++ +++   A DG
Sbjct: 369 IDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLV-TATSLDREQISEYNISLRASDG 427

Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
           G+PP S+   + + + DIND+PP F     + YI EN+P G +I  + A DPD   NA +
Sbjct: 428 GSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNNNARI 487

Query: 723 HYSIKGGD-DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--PPLWNDVR 779
            Y++          S      S+   L  +   DYE  R    LV  + S  PPL ++V 
Sbjct: 488 TYALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNVS 547

Query: 780 VEILVTDVNDNAP 792
           + + V D NDNAP
Sbjct: 548 LNLFVLDQNDNAP 560



 Score =  177 bits (432), Expect = 3e-42
 Identities = 140/468 (29%), Positives = 213/468 (45%), Gaps = 38/468 (8%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           +H Q+ VLD ND+ P+F   +Y  SV E    GT +LT+ ATD D G NA+V Y ++ + 
Sbjct: 226 LHIQVIVLDANDNPPMFTQPEYRVSVWENVPVGTRLLTVNATDPDEGFNAQVSYILDKMP 285

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
                              + ++F ++  SG +    SLD E    Y + ++A D     
Sbjct: 286 GK-----------------IAEIFHLNSVSGEVSILKSLDYEDAMFYEIKIEAQDGPG-- 326

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
              L S A I V ++D NDN P+ +  + T SV E+ +V     IA I   D D G N  
Sbjct: 327 ---LLSRAKILVTVLDVNDNAPEITITSLTSSVPEEGTVGRE--IALIDVHDRDSGQNGQ 381

Query: 187 IRYAIIGGNT-QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
           +   ++G    +++ SID     V+   +LD EQ+  Y + +RA DGGSP  S  T + +
Sbjct: 382 VEVFVLGNLPFKLEKSIDQYYRLVTAT-SLDREQISEYNISLRASDGGSPPLSTETHITL 440

Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-N 304
           ++ D+NDN P F    +   + EN P G SI  V A D D   NA +TY +T+    G  
Sbjct: 441 HVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNNNARITYALTEDTLQGAP 500

Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
           +   ++I+  +G +Y     D E     +LLVTA+D G+PP S+  +             
Sbjct: 501 LSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNVSLNLFVLDQNDNAP 560

Query: 365 XFM------PGQYEVELA-EDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSIT 415
             +       G   VELA     PG  V  + A D D      L Y +   +  G FS+ 
Sbjct: 561 EILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVG 620

Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDAN 463
              G   +  A+ L  +   +  L V+  D G    +A V + +  A+
Sbjct: 621 LHTGE--VRTARALLDRDALKQSLVVAIQDHGQPPLSATVTLIVAVAD 666



 Score =  133 bits (321), Expect = 8e-29
 Identities = 96/280 (34%), Positives = 138/280 (49%), Gaps = 16/280 (5%)

Query: 522 QQFVINPQTGAITTNKLLDRETMSGYL-LTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580
           Q F +NPQ+G++ T + +DRE +   + L +   +  V       +VEI + D+NDN P 
Sbjct: 73  QLFSLNPQSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDINDNAPN 132

Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS-GV- 638
           F  +     I E  + GT      A D DVG+N   +Y+L P D    S  ++  S G  
Sbjct: 133 FPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPND--YFSLAVNSVSEGAK 190

Query: 639 ---IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695
              +   +ALDRE    H L  VA DGG P  S  + + + + D ND+PP+F        
Sbjct: 191 YPELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRVS 250

Query: 696 ISENSPIGTTIGEIRAHDPDEGPNAVVHYSI--KGGDDSNSFSLETRQGSDKAELVTMVD 753
           + EN P+GT +  + A DPDEG NA V Y +    G  +  F L +  G    E+  +  
Sbjct: 251 VWENVPVGTRLLTVNATDPDEGFNAQVSYILDKMPGKIAEIFHLNSVSG----EVSILKS 306

Query: 754 LDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAP 792
           LDYE     YE+ I A   P L +  ++ + V DVNDNAP
Sbjct: 307 LDYED-AMFYEIKIEAQDGPGLLSRAKILVTVLDVNDNAP 345



 Score = 72.9 bits (171), Expect = 1e-10
 Identities = 75/284 (26%), Positives = 129/284 (45%), Gaps = 14/284 (4%)

Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGS---FVIDPASGVIRTNKALDRESVATH-DLK 656
           S VG    D+GL  R   E   +    G    F ++P SG + T + +DRE +     L 
Sbjct: 43  SFVGNIANDLGLEPRELAERGVRIVSRGRTQLFSLNPQSGSLVTAERIDREELCAQIPLC 102

Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
            V I+     +     V I+I+DIND+ P F ++ L   I E +  GT      A DPD 
Sbjct: 103 LVKINILVEDKLKIFEVEIEIKDINDNAPNFPTEELEIKIGELTVPGTRFPIKTAFDPDV 162

Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PP 773
           G N++ +Y +   D  +       +G+   ELV    LD E  ++ ++LV+ A+    P 
Sbjct: 163 GINSLQNYKLSPNDYFSLAVNSVSEGAKYPELVLERALDREK-KEIHQLVLVASDGGDPV 221

Query: 774 LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDAD--VTDKLQYR 830
              ++ ++++V D NDN P+    +   + +++  PVG     V A D D     ++ Y 
Sbjct: 222 HSGNLHIQVIVLDANDNPPMFTQPEYRVSVWEN-VPVGTRLLTVNATDPDEGFNAQVSYI 280

Query: 831 I--LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
           +  + G  A +  LN  +G +++   L+        +++   DG
Sbjct: 281 LDKMPGKIAEIFHLNSVSGEVSILKSLDYEDAMFYEIKIEAQDG 324


>UniRef50_UPI00006A0F40 Cluster: Protocadherin gamma C3 precursor
           (PCDH-gamma-C3) (Protocadherin 43) (PC-43)
           (Protocadherin 2).; n=2; Xenopus tropicalis|Rep:
           Protocadherin gamma C3 precursor (PCDH-gamma-C3)
           (Protocadherin 43) (PC-43) (Protocadherin 2). - Xenopus
           tropicalis
          Length = 932

 Score =  204 bits (498), Expect = 3e-50
 Identities = 167/584 (28%), Positives = 270/584 (46%), Gaps = 55/584 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ +LD ND+SP F+  +    + E AS G   L   A D DIG NA  EY         
Sbjct: 122 EVEILDINDNSPRFQGDELTLKINELASPGARFLIPNAQDPDIGSNALQEY--------H 173

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
           L+P +                R DG +   L+   +LDRE+ A + +++KA D   P   
Sbjct: 174 LSPSENFALIVKK--------RTDGSKFPELILEKALDREQTAVHHLVLKAEDGGVP--- 222

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             SST  I+V ++D NDN+P F + +Y V + E  +   N ++ K+ ATD D G N  I 
Sbjct: 223 SRSSTMQINVIVLDANDNHPAFDQPSYNVQLKE--NAPKNSLVIKLNATDLDEGPNGEIE 280

Query: 189 YAIIGGNTQMQ---FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
           Y     N+      F ++S +G++ ++  LD+E+V  Y + I A+D G+P       +++
Sbjct: 281 YFFSSHNSDALSNIFQLNSETGEIRVLGNLDFEEVSVYEIDIEARDKGTPIMEEHCSVIV 340

Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
           +I DVNDN P    S F  SV E+ P G  +  +   D D G N  +     DK    N+
Sbjct: 341 HIIDVNDNTPEMTISAFSSSVPEDSPAGTVVAVITIKDKDHGDNGRV-QCQVDK----NI 395

Query: 306 DLPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
              +  D    + + TS  LDRE+ ++Y + +TA D G+PP S                 
Sbjct: 396 PFTVREDFEHQFSLITSDNLDRESVSEYHITITAKDMGNPPLSTEKVISVVVSDVNDNAP 455

Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTAT--DADEDNRLHYEITGG-----NTRGRFSITSQ 417
            F+   YEV + E+   G  + T++A+  D D+++RL Y I         +     I S+
Sbjct: 456 QFVEPVYEVFVEENNKAGELLCTVSASDPDLDQNSRLSYTIIQNPKEDYASSSHIYINSE 515

Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYT 475
           NG+  + +  PLD+++   +   +   D+G     +  +V + + D N+ APV       
Sbjct: 516 NGQ--VYLKFPLDYERINYFRFQIEVADAGSPPLKNKTVVHVFVLDQNDNAPVVVFPIVG 573

Query: 476 ASVFEDAPI----GTTVLV--VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
           A+      I    G  V+V  +SA D D G NA ++Y+L         A     F +  +
Sbjct: 574 ANSVAHCKIPLLTGPNVMVSKISAVDYDSGRNAWLSYNLLD-------ATDPTLFSVVLR 626

Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
           TG I T + +     + + L +  +D G P LS +  V +++ D
Sbjct: 627 TGEIKTKRAIQDIDPTIHELLLLVKDSGDPCLSTSVTVMMTLED 670



 Score =  204 bits (497), Expect = 4e-50
 Identities = 164/607 (27%), Positives = 271/607 (44%), Gaps = 30/607 (4%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F I+  +GA+L    +DRE +   +V      + +   +       I V I+D NDN P+
Sbjct: 77  FSINVNNGAILVNDRIDRELLCAQSVTCILNLKFA--IENPVEVYRIEVEILDINDNSPR 134

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG-- 207
           F     T+ ++E  S     +I    A D D+G+N+   Y +               G  
Sbjct: 135 FQGDELTLKINELASPGARFLIPN--AQDPDIGSNALQEYHLSPSENFALIVKKRTDGSK 192

Query: 208 --DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265
             ++ L K LD EQ   + LV++A+DGG PSRS+T Q+ + + D NDN P F    +   
Sbjct: 193 FPELILEKALDREQTAVHHLVLKAEDGGVPSRSSTMQINVIVLDANDNHPAFDQPSYNVQ 252

Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMT--DKDYTGNVDLPITIDPRSGWVYTSGQ 323
           + EN P    ++++ A D DEG N E+ Y  +  + D   N+     ++  +G +   G 
Sbjct: 253 LKENAPKNSLVIKLNATDLDEGPNGEIEYFFSSHNSDALSNI---FQLNSETGEIRVLGN 309

Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383
           LD E  + Y++ + A D G P      +                   +   + ED P GT
Sbjct: 310 LDFEEVSVYEIDIEARDKGTPIMEEHCSVIVHIIDVNDNTPEMTISAFSSSVPEDSPAGT 369

Query: 384 PVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441
            V  +T  D D  ++ R+  ++   N         ++   LIT +  LD +    Y +T+
Sbjct: 370 VVAVITIKDKDHGDNGRVQCQV-DKNIPFTVREDFEHQFSLIT-SDNLDRESVSEYHITI 427

Query: 442 SATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499
           +A D G    S   ++ + ++D N+ AP F    Y   V E+   G  +  VSA+D D+ 
Sbjct: 428 TAKDMGNPPLSTEKVISVVVSDVNDNAPQFVEPVYEVFVEENNKAGELLCTVSASDPDLD 487

Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
            N++++Y++      +  +       IN + G +     LD E ++ +   +   D G P
Sbjct: 488 QNSRLSYTIIQNPKEDYAS--SSHIYINSENGQVYLKFPLDYERINYFRFQIEVADAGSP 545

Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA----LVGTS--VSQVGATDADVGLN 613
            L + T V + V+D NDN PV    +  AN +       L G +  VS++ A D D G N
Sbjct: 546 PLKNKTVVHVFVLDQNDNAPVVVFPIVGANSVAHCKIPLLTGPNVMVSKISAVDYDSGRN 605

Query: 614 GRIHYE-LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672
             + Y  LD  D    S V+   +G I+T +A+       H+L  +  D G P  S++V 
Sbjct: 606 AWLSYNLLDATDPTLFSVVL--RTGEIKTKRAIQDIDPTIHELLLLVKDSGDPCLSTSVT 663

Query: 673 VHIKIED 679
           V + +ED
Sbjct: 664 VMMTLED 670



 Score =  188 bits (457), Expect = 3e-45
 Identities = 135/463 (29%), Positives = 227/463 (49%), Gaps = 20/463 (4%)

Query: 423 ITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
           + + + LD +Q   + L + A D G   RS T  + + + DAN+  P F+   Y   + E
Sbjct: 196 LILEKALDREQTAVHHLVLKAEDGGVPSRSSTMQINVIVLDANDNHPAFDQPSYNVQLKE 255

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           +AP  + V+ ++ATD D G N +I Y  SS  +++A+++    F +N +TG I     LD
Sbjct: 256 NAPKNSLVIKLNATDLDEGPNGEIEYFFSSH-NSDALSNI---FQLNSETGEIRVLGNLD 311

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
            E +S Y + + ARD G P + +   V + ++DVNDN P      +++++ ED+  GT V
Sbjct: 312 FEEVSVYEIDIEARDKGTPIMEEHCSVIVHIIDVNDNTPEMTISAFSSSVPEDSPAGTVV 371

Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
           + +   D D G NGR+  ++D           +    +I T+  LDRESV+ + +   A 
Sbjct: 372 AVITIKDKDHGDNGRVQCQVDKNIPFTVREDFEHQFSLI-TSDNLDRESVSEYHITITAK 430

Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
           D G PP S+  ++ + + D+ND+ P F       ++ EN+  G  +  + A DPD   N+
Sbjct: 431 DMGNPPLSTEKVISVVVSDVNDNAPQFVEPVYEVFVEENNKAGELLCTVSASDPDLDQNS 490

Query: 721 VVHYS-IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYEL-VIRAASPPLWND 777
            + Y+ I+   +  + S      S+  ++     LDYE     ++++ V  A SPPL N 
Sbjct: 491 RLSYTIIQNPKEDYASSSHIYINSENGQVYLKFPLDYERINYFRFQIEVADAGSPPLKNK 550

Query: 778 VRVEILVTDVNDNAPVMKDFQII-FNNYKDC-FPV--GP---FGRVPA--YDADVTDKLQ 828
             V + V D NDNAPV+  F I+  N+   C  P+  GP     ++ A  YD+     L 
Sbjct: 551 TVVHVFVLDQNDNAPVVV-FPIVGANSVAHCKIPLLTGPNVMVSKISAVDYDSGRNAWLS 609

Query: 829 YRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
           Y +L   +  L  +   TG +     +    P +  + + V D
Sbjct: 610 YNLLDATDPTLFSVVLRTGEIKTKRAIQDIDPTIHELLLLVKD 652



 Score =  128 bits (308), Expect = 3e-27
 Identities = 86/282 (30%), Positives = 134/282 (47%), Gaps = 13/282 (4%)

Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLT-VTARDGGVPSLSDTTDVEISVVDVNDNEPV 580
           Q F IN   GAI  N  +DRE +    +T +      + +  +   +E+ ++D+NDN P 
Sbjct: 75  QYFSINVNNGAILVNDRIDRELLCAQSVTCILNLKFAIENPVEVYRIEVEILDINDNSPR 134

Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640
           F+    T  I E A  G       A D D+G N    Y L P   E  + ++   +   +
Sbjct: 135 FQGDELTLKINELASPGARFLIPNAQDPDIGSNALQEYHLSPS--ENFALIVKKRTDGSK 192

Query: 641 -----TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695
                  KALDRE  A H L   A DGG P +SST+ +++ + D ND+ P F+       
Sbjct: 193 FPELILEKALDREQTAVHHLVLKAEDGGVPSRSSTMQINVIVLDANDNHPAFDQPSYNVQ 252

Query: 696 ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755
           + EN+P  + + ++ A D DEGPN  + Y      +S++ S   +  S+  E+  + +LD
Sbjct: 253 LKENAPKNSLVIKLNATDLDEGPNGEIEYFF-SSHNSDALSNIFQLNSETGEIRVLGNLD 311

Query: 756 YESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVM 794
           +E     YE+ I A    +P +     V + + DVNDN P M
Sbjct: 312 FEEV-SVYEIDIEARDKGTPIMEEHCSVIVHIIDVNDNTPEM 352


>UniRef50_O93509 Cluster: Paraxial protocadherin; n=11; Xenopus|Rep:
           Paraxial protocadherin - Xenopus laevis (African clawed
           frog)
          Length = 979

 Score =  204 bits (497), Expect = 4e-50
 Identities = 173/606 (28%), Positives = 280/606 (46%), Gaps = 39/606 (6%)

Query: 207 GDVSLVKTLDYEQVRSYRLVIR-AQDGGSPSRSNTTQL--LINIRDVNDNAPRFYTSLFQ 263
           G +S+++ +D EQ+    L    A D  S S+ +   L   + +RD+ND++P F + +  
Sbjct: 76  GQLSIMERIDREQICRQSLHCNLALDVVSFSKGHFKLLNVKVEVRDINDHSPHFPSEIMH 135

Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP-RSGWVYTSG 322
             VSE+  +G  I    A D D G N+   + +++  +  ++D+    D  +   +    
Sbjct: 136 VEVSESSSVGTRIPLEIAIDEDVGSNSIQNFQISNNSHF-SIDVLTRADGVKYADLVLMR 194

Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382
           +LDRE Q  Y + + A DGG P  S TA               F      V+L ED P G
Sbjct: 195 ELDREIQPTYIMELLAMDGGVPSLSGTAVVNIRVLDFNDNSPVFERSTIAVDLVEDAPLG 254

Query: 383 TPVVTLTATDADE--DNRLHY---EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437
             ++ L ATD DE  +  + Y    +     R  F I S+ G   +T+   +DF+ ++ Y
Sbjct: 255 YLLLELHATDDDEGVNGEIVYGFSTLASQEVRQLFKINSRTGS--VTLEGQVDFETKQTY 312

Query: 438 VLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYT------ASVFEDAPIGTTVL 489
              V A D G    + T  V ++I D N+  P     P T      A + E A     + 
Sbjct: 313 EFEVQAQDLGPNPLTATCKVTVHILDVNDNTPAITITPLTTVNAGVAYIPETATKENFIA 372

Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
           ++S TD   G N Q+  +L      +    ++  ++       I T   LDRE ++ Y L
Sbjct: 373 LISTTDRASGSNGQVRCTLYGHEHFKLQQAYEDSYM-------IVTTSTLDRENIAAYSL 425

Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
           TV A D G PSL       + V D NDN PVF +  Y A+I+E+   G+ ++ V A D+D
Sbjct: 426 TVVAEDLGFPSLKTKKYYTVKVSDENDNAPVFSKPQYEASILENNAPGSYITTVIARDSD 485

Query: 610 VGLNGRIHYEL-DPKDREEG--SFV-IDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
              NG+++Y L D K   +   +FV +D  SGV+R  ++LD E +   D +  A D G P
Sbjct: 486 SDQNGKVNYRLVDAKVMGQSLTTFVSLDADSGVLRAVRSLDYEKLKQLDFEIEAADNGIP 545

Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISE-----NSPIGTTIGEIRAHDPDEGPNA 720
             S+ V ++++I D ND+ PV  +  L     E     ++P    + +++A D DEG N+
Sbjct: 546 QLSTRVQLNLRIVDQNDNCPVITNPLLNNGSGEVLLPISAPQNYLVFQLKAEDSDEGHNS 605

Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRV 780
            + Y+I   D S  F++    G  +  L   ++ D+         V     P L  +  V
Sbjct: 606 QLFYTIL-RDPSRLFAINKESG--EVFLKKQLNSDHSEDLSIVVAVYDLGRPSLSTNATV 662

Query: 781 EILVTD 786
           + ++TD
Sbjct: 663 KFILTD 668



 Score =  178 bits (433), Expect = 2e-42
 Identities = 167/608 (27%), Positives = 255/608 (41%), Gaps = 40/608 (6%)

Query: 97  GALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT 156
           G L     +DRE++ R ++           S        + V + D ND+ P F  +   
Sbjct: 76  GQLSIMERIDREQICRQSLHCNLALDVVSFSKGHFKLLNVKVEVRDINDHSPHFPSEIMH 135

Query: 157 VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS-------GDV 209
           V V E  SV     I    A D DVG+NS   + I   +    FSID L+        D+
Sbjct: 136 VEVSESSSVGTR--IPLEIAIDEDVGSNSIQNFQI---SNNSHFSIDVLTRADGVKYADL 190

Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269
            L++ LD E   +Y + + A DGG PS S T  + I + D NDN+P F  S     + E+
Sbjct: 191 VLMRELDREIQPTYIMELLAMDGGVPSLSGTAVVNIRVLDFNDNSPVFERSTIAVDLVED 250

Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329
            P+GY ++ + A D DEGVN E+ Y  +    +  V     I+ R+G V   GQ+D ET+
Sbjct: 251 APLGYLLLELHATDDDEGVNGEIVYGFSTL-ASQEVRQLFKINSRTGSVTLEGQVDFETK 309

Query: 330 AKYQLLVTATDGGDPPRSAT--ATXXXXXXXXXXXXXXFMP----GQYEVELAEDEPPGT 383
             Y+  V A D G  P +AT   T                P          + E      
Sbjct: 310 QTYEFEVQAQDLGPNPLTATCKVTVHILDVNDNTPAITITPLTTVNAGVAYIPETATKEN 369

Query: 384 PVVTLTATDADEDNRLHYEIT-GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
            +  ++ TD    +      T  G+   +     ++   ++T +  LD +    Y LTV 
Sbjct: 370 FIALISTTDRASGSNGQVRCTLYGHEHFKLQQAYEDSYMIVTTS-TLDRENIAAYSLTVV 428

Query: 443 ATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
           A D G  S        + ++D N+ APVF    Y AS+ E+   G+ +  V A DSD   
Sbjct: 429 AEDLGFPSLKTKKYYTVKVSDENDNAPVFSKPQYEASILENNAPGSYITTVIARDSDSDQ 488

Query: 501 NAQITYSLSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
           N ++ Y L   +  + +      FV ++  +G +   + LD E +      + A D G+P
Sbjct: 489 NGKVNYRL---VDAKVMGQSLTTFVSLDADSGVLRAVRSLDYEKLKQLDFEIEAADNGIP 545

Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS------VSQVGATDADVGLN 613
            LS    + + +VD NDN PV    L   N   + L+  S      V Q+ A D+D G N
Sbjct: 546 QLSTRVQLNLRIVDQNDNCPVITNPLLN-NGSGEVLLPISAPQNYLVFQLKAEDSDEGHN 604

Query: 614 GRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671
            ++ Y +  DP       F I+  SG +   K L+ +      +     D G P  S+  
Sbjct: 605 SQLFYTILRDP----SRLFAINKESGEVFLKKQLNSDHSEDLSIVVAVYDLGRPSLSTNA 660

Query: 672 IVHIKIED 679
            V   + D
Sbjct: 661 TVKFILTD 668



 Score =  172 bits (419), Expect = 1e-40
 Identities = 156/590 (26%), Positives = 252/590 (42%), Gaps = 57/590 (9%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           ++ ++ V D NDHSP F  +     V E +S GT +    A D+D+G N+   + I    
Sbjct: 113 LNVKVEVRDINDHSPHFPSEIMHVEVSESSSVGTRIPLEIAIDEDVGSNSIQNFQI---- 168

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASP 125
                              +  + R DG +   L+    LDRE    Y + + A D   P
Sbjct: 169 ------------SNNSHFSIDVLTRADGVKYADLVLMRELDREIQPTYIMELLAMDGGVP 216

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
               LS TA +++ ++D NDN P F   T  V + ED  +    ++ ++ ATD D G N 
Sbjct: 217 ---SLSGTAVVNIRVLDFNDNSPVFERSTIAVDLVEDAPL--GYLLLELHATDDDEGVNG 271

Query: 186 AIRY---AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
            I Y    +     +  F I+S +G V+L   +D+E  ++Y   ++AQD G    + T +
Sbjct: 272 EIVYGFSTLASQEVRQLFKINSRTGSVTLEGQVDFETKQTYEFEVQAQDLGPNPLTATCK 331

Query: 243 LLINIRDVNDNAPRF-YTSLFQES-----VSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
           + ++I DVNDN P    T L   +     + E       I  +   D   G N ++  T+
Sbjct: 332 VTVHILDVNDNTPAITITPLTTVNAGVAYIPETATKENFIALISTTDRASGSNGQVRCTL 391

Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
              ++     L    +  S  + T+  LDRE  A Y L V A D G P            
Sbjct: 392 YGHEH---FKLQQAYED-SYMIVTTSTLDRENIAAYSLTVVAEDLGFPSLKTKKYYTVKV 447

Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSI 414
                    F   QYE  + E+  PG+ + T+ A D+D D   +++Y +      G+ S+
Sbjct: 448 SDENDNAPVFSKPQYEASILENNAPGSYITTVIARDSDSDQNGKVNYRLVDAKVMGQ-SL 506

Query: 415 TS----QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYAPV 468
           T+        G++   + LD+++ ++    + A D+G    +  VQ+N  I D N+  PV
Sbjct: 507 TTFVSLDADSGVLRAVRSLDYEKLKQLDFEIEAADNGIPQLSTRVQLNLRIVDQNDNCPV 566

Query: 469 FENAPYTASVFE-----DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523
             N        E      AP    V  + A DSD G N+Q+ Y++  + S        + 
Sbjct: 567 ITNPLLNNGSGEVLLPISAPQNYLVFQLKAEDSDEGHNSQLFYTILRDPS--------RL 618

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
           F IN ++G +   K L+ +      + V   D G PSLS    V+  + D
Sbjct: 619 FAINKESGEVFLKKQLNSDHSEDLSIVVAVYDLGRPSLSTNATVKFILTD 668



 Score =  155 bits (375), Expect = 2e-35
 Identities = 154/574 (26%), Positives = 254/574 (44%), Gaps = 47/574 (8%)

Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS---ITSQNGRGLITVA 426
           QY ++  E+EPPGT +  L+       N      T      +F+   I  +   G +++ 
Sbjct: 26  QYYID--EEEPPGTVIAVLSQHSIF--NTTDIPATNFRLMKQFNNSLIGVRESDGQLSIM 81

Query: 427 QPLDFKQERRYVLTVS-ATD----SGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
           + +D +Q  R  L  + A D    S G      V++ + D N+++P F +      V E 
Sbjct: 82  ERIDREQICRQSLHCNLALDVVSFSKGHFKLLNVKVEVRDINDHSPHFPSEIMHVEVSES 141

Query: 482 APIGTTVLVVSATDSDVGINAQITYSLS--SEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           + +GT + +  A D DVG N+   + +S  S  S + +   D       +   +   + L
Sbjct: 142 SSVGTRIPLEIAIDEDVGSNSIQNFQISNNSHFSIDVLTRAD-----GVKYADLVLMREL 196

Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
           DRE    Y++ + A DGGVPSLS T  V I V+D NDN PVF++     +++EDA +G  
Sbjct: 197 DREIQPTYIMELLAMDGGVPSLSGTAVVNIRVLDFNDNSPVFERSTIAVDLVEDAPLGYL 256

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREE--GSFVIDPASGVIRTNKALDRESVATHDLKA 657
           + ++ ATD D G+NG I Y       +E    F I+  +G +     +D E+  T++ + 
Sbjct: 257 LLELHATDDDEGVNGEIVYGFSTLASQEVRQLFKINSRTGSVTLEGQVDFETKQTYEFEV 316

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT------FYISENSPIGTTIGEIRA 711
            A D G  P ++T  V + I D+ND+ P      LT       YI E +     I  I  
Sbjct: 317 QAQDLGPNPLTATCKVTVHILDVNDNTPAITITPLTTVNAGVAYIPETATKENFIALIST 376

Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771
            D   G N  V  ++ G +    F L+ +   D   +VT   LD E+    Y L + A  
Sbjct: 377 TDRASGSNGQVRCTLYGHE---HFKLQ-QAYEDSYMIVTTSTLDREN-IAAYSLTVVAED 431

Query: 772 ---PPLWNDVRVEILVTDVNDNAPVMK----DFQIIFNNYKDCFPVGPFGRVPAYDADVT 824
              P L       + V+D NDNAPV      +  I+ NN    +      R    D+D  
Sbjct: 432 LGFPSLKTKKYYTVKVSDENDNAPVFSKPQYEASILENNAPGSYITTVIAR--DSDSDQN 489

Query: 825 DKLQYR-----ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKA 878
            K+ YR     ++  +    + L+  +G +     L+    K    E+   D G+ ++  
Sbjct: 490 GKVNYRLVDAKVMGQSLTTFVSLDADSGVLRAVRSLDYEKLKQLDFEIEAADNGIPQLST 549

Query: 879 MMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPL 912
            +QL++R++ +      IT  L +  + + L P+
Sbjct: 550 RVQLNLRIVDQNDNCPVITNPLLNNGSGEVLLPI 583



 Score =  134 bits (324), Expect = 3e-29
 Identities = 128/466 (27%), Positives = 199/466 (42%), Gaps = 36/466 (7%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I VLD ND+SPVFE       + E A  G  +L L ATD D G N E+ Y        TL
Sbjct: 226 IRVLDFNDNSPVFERSTIAVDLVEDAPLGYLLLELHATDDDEGVNGEIVYGFS-----TL 280

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             ++           V+ +F+I+ R+G++     +D E    Y   V+A D      + L
Sbjct: 281 ASQE-----------VRQLFKINSRTGSVTLEGQVDFETKQTYEFEVQAQDLGP---NPL 326

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS-----VTDNPVIAKIKATDADVGANS 185
           ++T  + V+I+D NDN P  +    T +V+  ++      T    IA I  TD   G+N 
Sbjct: 327 TATCKVTVHILDVNDNTPAITITPLT-TVNAGVAYIPETATKENFIALISTTDRASGSNG 385

Query: 186 AIRYAIIGG-NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
            +R  + G  + ++Q + +  S  +    TLD E + +Y L + A+D G PS        
Sbjct: 386 QVRCTLYGHEHFKLQQAYED-SYMIVTTSTLDRENIAAYSLTVVAEDLGFPSLKTKKYYT 444

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG- 303
           + + D NDNAP F    ++ S+ EN   G  I  V A D+D   N ++ Y + D    G 
Sbjct: 445 VKVSDENDNAPVFSKPQYEASILENNAPGSYITTVIARDSDSDQNGKVNYRLVDAKVMGQ 504

Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX---- 359
           ++   +++D  SG +     LD E   +    + A D G P  S                
Sbjct: 505 SLTTFVSLDADSGVLRAVRSLDYEKLKQLDFEIEAADNGIPQLSTRVQLNLRIVDQNDNC 564

Query: 360 -XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITS 416
                     G  EV L    P    V  L A D+DE  +++L Y I    +R  F+I  
Sbjct: 565 PVITNPLLNNGSGEVLLPISAPQNYLVFQLKAEDSDEGHNSQLFYTILRDPSR-LFAINK 623

Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDA 462
           ++G   +      D  ++   V+ V        S  A V+  +TD+
Sbjct: 624 ESGEVFLKKQLNSDHSEDLSIVVAVYDLGRPSLSTNATVKFILTDS 669



 Score = 99.5 bits (237), Expect = 1e-18
 Identities = 82/272 (30%), Positives = 127/272 (46%), Gaps = 27/272 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + V D ND++PVF   QYEAS+ E  + G+ + T+ A D D  +N +V Y   LV A  +
Sbjct: 445 VKVSDENDNAPVFSKPQYEASILENNAPGSYITTVIARDSDSDQNGKVNY--RLVDAKVM 502

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                          +     +D  SG L    SLD EK+ +    ++A D   P   +L
Sbjct: 503 GQS------------LTTFVSLDADSGVLRAVRSLDYEKLKQLDFEIEAADNGIP---QL 547

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDE---DISVTDNPVIAKIKATDADVGANSAI 187
           S+   +++ I+D NDN P  +         E    IS   N ++ ++KA D+D G NS +
Sbjct: 548 STRVQLNLRIVDQNDNCPVITNPLLNNGSGEVLLPISAPQNYLVFQLKAEDSDEGHNSQL 607

Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS-NTTQLLIN 246
            Y I+   +++ F+I+  SG+V L K L+ +      +V+   D G PS S N T   I 
Sbjct: 608 FYTILRDPSRL-FAINKESGEVFLKKQLNSDHSEDLSIVVAVYDLGRPSLSTNATVKFI- 665

Query: 247 IRDVNDNAP-RFYTSLFQESVSENVPIGYSIV 277
              + D+ P      + Q S  E   I  SI+
Sbjct: 666 ---LTDSFPSNVEVVILQPSAEEQHQIDMSII 694


>UniRef50_Q6EI13 Cluster: GammaA-like protocadherin precursor; n=5;
           Gallus gallus|Rep: GammaA-like protocadherin precursor -
           Gallus gallus (Chicken)
          Length = 811

 Score =  203 bits (496), Expect = 5e-50
 Identities = 162/549 (29%), Positives = 244/549 (44%), Gaps = 23/549 (4%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F +   SG L+T   +DRE++ R  +L K   +   + +       I V I D NDN P 
Sbjct: 76  FVLHASSGHLVTAERIDREQLCR--LLEKCVLRCELIVEGEMKVYPIEVEITDINDNTPS 133

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG---NTQMQFSIDSLS 206
           F E    +  +E   +     + +  A D D+G NS   YA+ G    +  +Q   D   
Sbjct: 134 FGEGQIELRTNEMAVIGMRYALRR--AHDPDMGTNSLQSYALSGDEHFSLSVQAGADGEK 191

Query: 207 G-DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265
             ++ L K LD E+   + L++RA DGG P+R+ T ++ + + D NDNAP F  +++   
Sbjct: 192 RPELVLAKALDREEAAFHELLLRASDGGDPARTGTARIRVAVLDANDNAPAFSQAVYTVR 251

Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325
           V E+VP+G +++RV A D D+G N ++ Y    ++    +     I+P++G +     LD
Sbjct: 252 VPEDVPVGSTLLRVTATDPDDGTNGDVKYLF--QEVLEQISNTFHIEPKTGAIRLVRNLD 309

Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
            E    Y+ LV A DGG     A  T                    E+  +ED  PGT V
Sbjct: 310 FEEADFYEFLVQAHDGGGLSDDAKITVSVTDVNDNAPEISVRSALSEI--SEDAAPGTVV 367

Query: 386 VTLTATDADEDNRLHYEIT-GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444
             L   D D         + G     R      +   ++T A+ LD ++   Y +TV A 
Sbjct: 368 ALLHVQDRDSGANGEVRCSLGEGVPFRLERALDDYYSVVT-ARELDRERASEYNVTVRAA 426

Query: 445 DSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502
           D G  +    A++ + + D N+ APVF  A Y+A + E+   G  VL V A D+D G NA
Sbjct: 427 DGGSPALRSGAVLALRVLDVNDNAPVFAEARYSARLPENNAEGALVLTVRAWDADWGQNA 486

Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
           ++ Y L         A       +  +TGA+   +  D E +    L V A DGG P LS
Sbjct: 487 RVRYRLRE--GRLRGAPLSSYVSVQAETGALYALRSFDYEEVREVELWVRAEDGGAPPLS 544

Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP 622
               V + + D NDN P   Q LY            S + VGA  +  G       EL P
Sbjct: 545 SNVSVRLLIADENDNAP---QVLYPPAAPGPG--PGSGAGVGAWGSASGAWSWAGVELAP 599

Query: 623 KDREEGSFV 631
           +  E G+ V
Sbjct: 600 RSAEPGALV 608



 Score =  202 bits (492), Expect = 1e-49
 Identities = 147/440 (33%), Positives = 215/440 (48%), Gaps = 25/440 (5%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLH-YEITGGNTRGRFSITSQNG---- 419
           F  GQ E+   E    G       A D D   N L  Y ++G      FS++ Q G    
Sbjct: 134 FGEGQIELRTNEMAVIGMRYALRRAHDPDMGTNSLQSYALSGDE---HFSLSVQAGADGE 190

Query: 420 -RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTA 476
            R  + +A+ LD ++   + L + A+D G   R+ TA +++ + DAN+ AP F  A YT 
Sbjct: 191 KRPELVLAKALDREEAAFHELLLRASDGGDPARTGTARIRVAVLDANDNAPAFSQAVYTV 250

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
            V ED P+G+T+L V+ATD D G N  + Y     +  E +      F I P+TGAI   
Sbjct: 251 RVPEDVPVGSTLLRVTATDPDDGTNGDVKY-----LFQEVLEQISNTFHIEPKTGAIRLV 305

Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
           + LD E    Y   V A DGG   LSD   + +SV DVNDN P    +   + I EDA  
Sbjct: 306 RNLDFEEADFYEFLVQAHDGG--GLSDDAKITVSVTDVNDNAPEISVRSALSEISEDAAP 363

Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
           GT V+ +   D D G NG +   L           +D    V+ T + LDRE  + +++ 
Sbjct: 364 GTVVALLHVQDRDSGANGEVRCSLGEGVPFRLERALDDYYSVV-TARELDRERASEYNVT 422

Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
             A DGG+P   S  ++ +++ D+ND+ PVF     +  + EN+  G  +  +RA D D 
Sbjct: 423 VRAADGGSPALRSGAVLALRVLDVNDNAPVFAEARYSARLPENNAEGALVLTVRAWDADW 482

Query: 717 GPNAVVHYSIKGGDDSNS-FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASP 772
           G NA V Y ++ G    +  S      ++   L  +   DYE  R + EL +RA    +P
Sbjct: 483 GQNARVRYRLREGRLRGAPLSSYVSVQAETGALYALRSFDYEEVR-EVELWVRAEDGGAP 541

Query: 773 PLWNDVRVEILVTDVNDNAP 792
           PL ++V V +L+ D NDNAP
Sbjct: 542 PLSSNVSVRLLIADENDNAP 561



 Score =  158 bits (383), Expect = 2e-36
 Identities = 119/386 (30%), Positives = 184/386 (47%), Gaps = 16/386 (4%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           +++ ITD N+  P F          E A IG    +  A D D+G N+  +Y+LS +   
Sbjct: 120 IEVEITDINDNTPSFGEGQIELRTNEMAVIGMRYALRRAHDPDMGTNSLQSYALSGD--- 176

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
           E  +   Q      +   +   K LDRE  + + L + A DGG P+ + T  + ++V+D 
Sbjct: 177 EHFSLSVQAGADGEKRPELVLAKALDREEAAFHELLLRASDGGDPARTGTARIRVAVLDA 236

Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFVID 633
           NDN P F Q +YT  + ED  VG+++ +V ATD D G NG + Y   +  ++   +F I+
Sbjct: 237 NDNAPAFSQAVYTVRVPEDVPVGSTLLRVTATDPDDGTNGDVKYLFQEVLEQISNTFHIE 296

Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693
           P +G IR  + LD E    ++    A DGG     + + V   + D+ND+ P        
Sbjct: 297 PKTGAIRLVRNLDFEEADFYEFLVQAHDGGGLSDDAKITV--SVTDVNDNAPEISVRSAL 354

Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753
             ISE++  GT +  +   D D G N  V  S+  G     F LE R   D   +VT  +
Sbjct: 355 SEISEDAAPGTVVALLHVQDRDSGANGEVRCSLGEGVP---FRLE-RALDDYYSVVTARE 410

Query: 754 LDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV 810
           LD E    +Y + +RAA   SP L +   + + V DVNDNAPV  + +      ++    
Sbjct: 411 LDRERA-SEYNVTVRAADGGSPALRSGAVLALRVLDVNDNAPVFAEARYSARLPENNAEG 469

Query: 811 GPFGRVPAYDAD--VTDKLQYRILSG 834
                V A+DAD     +++YR+  G
Sbjct: 470 ALVLTVRAWDADWGQNARVRYRLREG 495



 Score =  153 bits (371), Expect = 7e-35
 Identities = 104/344 (30%), Positives = 168/344 (48%), Gaps = 27/344 (7%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ VLD ND++P F    Y   V E    G+T+L + ATD D G N +V+Y  + V    
Sbjct: 230 RVAVLDANDNAPAFSQAVYTVRVPEDVPVGSTLLRVTATDPDDGTNGDVKYLFQEVLEQ- 288

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                           + + F I+ ++GA+    +LD E+   Y  LV+A D        
Sbjct: 289 ----------------ISNTFHIEPKTGAIRLVRNLDFEEADFYEFLVQAHDGGG----- 327

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           LS  A I V++ D NDN P+ S ++    + ED       V+A +   D D GAN  +R 
Sbjct: 328 LSDDAKITVSVTDVNDNAPEISVRSALSEISED--AAPGTVVALLHVQDRDSGANGEVRC 385

Query: 190 AI-IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
           ++  G   +++ ++D     V+  + LD E+   Y + +RA DGGSP+  +   L + + 
Sbjct: 386 SLGEGVPFRLERALDDYYSVVT-ARELDRERASEYNVTVRAADGGSPALRSGAVLALRVL 444

Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NVDL 307
           DVNDNAP F  + +   + EN   G  ++ V+A+DAD G NA + Y + +    G  +  
Sbjct: 445 DVNDNAPVFAEARYSARLPENNAEGALVLTVRAWDADWGQNARVRYRLREGRLRGAPLSS 504

Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
            +++   +G +Y     D E   + +L V A DGG PP S+  +
Sbjct: 505 YVSVQAETGALYALRSFDYEEVREVELWVRAEDGGAPPLSSNVS 548



 Score =  124 bits (300), Expect = 3e-26
 Identities = 90/279 (32%), Positives = 135/279 (48%), Gaps = 14/279 (5%)

Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVNDNEPV 580
           Q FV++  +G + T + +DRE +   L     R +  V        +E+ + D+NDN P 
Sbjct: 74  QYFVLHASSGHLVTAERIDREQLCRLLEKCVLRCELIVEGEMKVYPIEVEITDINDNTPS 133

Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640
           F +        E A++G   +   A D D+G N    Y L   D      V   A G  R
Sbjct: 134 FGEGQIELRTNEMAVIGMRYALRRAHDPDMGTNSLQSYALSG-DEHFSLSVQAGADGEKR 192

Query: 641 TN----KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696
                 KALDRE  A H+L   A DGG P ++ T  + + + D ND+ P F     T  +
Sbjct: 193 PELVLAKALDREEAAFHELLLRASDGGDPARTGTARIRVAVLDANDNAPAFSQAVYTVRV 252

Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG--GDDSNSFSLETRQGSDKAELVTMVDL 754
            E+ P+G+T+  + A DPD+G N  V Y  +      SN+F +E + G+    LV   +L
Sbjct: 253 PEDVPVGSTLLRVTATDPDDGTNGDVKYLFQEVLEQISNTFHIEPKTGA--IRLVR--NL 308

Query: 755 DYESPRKKYELVIRA-ASPPLWNDVRVEILVTDVNDNAP 792
           D+E     YE +++A     L +D ++ + VTDVNDNAP
Sbjct: 309 DFEE-ADFYEFLVQAHDGGGLSDDAKITVSVTDVNDNAP 346


>UniRef50_UPI0000E80EAB Cluster: PREDICTED: similar to Protocadherin
           beta 15 precursor (PCDH-beta15); n=6; Gallus gallus|Rep:
           PREDICTED: similar to Protocadherin beta 15 precursor
           (PCDH-beta15) - Gallus gallus
          Length = 927

 Score =  203 bits (495), Expect = 6e-50
 Identities = 144/501 (28%), Positives = 230/501 (45%), Gaps = 23/501 (4%)

Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV----RSYRLVIRAQDGGSPSRSNT 240
           +A +  ++   ++  F +D  SG +++ +TLD E++     S  L+ +          N 
Sbjct: 418 AARKARVVSEGSEQHFRLDPHSGVLTVTETLDRERICPHSESCALLFKL------FFENP 471

Query: 241 TQLL---INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297
            QL+   + +RDVND++P F        V E    G       A D D G+N    Y+++
Sbjct: 472 VQLIRGEVEVRDVNDHSPVFPQKEVVLEVLETASPGSRFSLESAQDEDVGINGLQNYSLS 531

Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357
              Y                +     LDRE Q +  L++TATDGG PPRS TA       
Sbjct: 532 PNPYFSLALEKWKGGAEFVKLVLQKPLDREEQRELHLVLTATDGGSPPRSGTAQVRVVVL 591

Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSIT 415
                   F    YEV +AE+ PPG  VV ++A D DE  + ++ Y  T  + + +    
Sbjct: 592 DANDNMPVFSREVYEVRVAENSPPGQLVVRVSAADPDEGSNGKVRYTFTEMSEQSQQLYE 651

Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYT 475
                G I V+  LD+++E+ + L V A D GG S    V + + D N+ AP    +  +
Sbjct: 652 LNPETGEIRVSGNLDYEEEKMHELVVRAMDGGGLSAHCRVHVEVLDVNDNAPEIALSSVS 711

Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
           AS+ EDAP  T V ++S  D D G N +   ++  ++     A     + +        T
Sbjct: 712 ASIPEDAPPRTVVALLSVRDRDSGDNGRTECAIEGDVPFSLTAAFANHYELR-------T 764

Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
           +  LDRET + Y +++ A D G   LS    V + + DVNDN P F Q  Y+ ++ E+  
Sbjct: 765 SAALDRETTAEYNVSIVATDWGRARLSARESVSVRIADVNDNAPRFTQAAYSMSVSENEA 824

Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV-IDPASGVIRTNKALDRESVATHD 654
               +  V ATDAD G NGR+ Y L  ++ EE   V +   S  +   +++D + V    
Sbjct: 825 GAVRIGSVKATDADAGANGRVRYALVREEGEERPDVSLYAESRPLSVVRSVDIDDVGAVK 884

Query: 655 LKAVAIDGGTPPQSSTVIVHI 675
                  GG+PP+S+  ++ +
Sbjct: 885 ATLRTAKGGSPPRSAATLLRL 905



 Score =  171 bits (415), Expect = 3e-40
 Identities = 116/353 (32%), Positives = 173/353 (49%), Gaps = 10/353 (2%)

Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480
           + + +PLD +++R   L ++ATD G   RS TA V++ + DAN+  PVF    Y   V E
Sbjct: 552 LVLQKPLDREEQRELHLVLTATDGGSPPRSGTAQVRVVVLDANDNMPVFSREVYEVRVAE 611

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           ++P G  V+ VSA D D G N ++ Y+ + E+S ++     Q + +NP+TG I  +  LD
Sbjct: 612 NSPPGQLVVRVSAADPDEGSNGKVRYTFT-EMSEQS----QQLYELNPETGEIRVSGNLD 666

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
            E    + L V A DGG   LS    V + V+DVNDN P       +A+I EDA   T V
Sbjct: 667 YEEEKMHELVVRAMDGG--GLSAHCRVHVEVLDVNDNAPEIALSSVSASIPEDAPPRTVV 724

Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
           + +   D D G NGR    ++  D              +RT+ ALDRE+ A +++  VA 
Sbjct: 725 ALLSVRDRDSGDNGRTECAIEG-DVPFSLTAAFANHYELRTSAALDRETTAEYNVSIVAT 783

Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
           D G    S+   V ++I D+ND+ P F     +  +SEN      IG ++A D D G N 
Sbjct: 784 DWGRARLSARESVSVRIADVNDNAPRFTQAAYSMSVSENEAGAVRIGSVKATDADAGANG 843

Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP 773
            V Y++   +      +     S    +V  VD+D     K      +  SPP
Sbjct: 844 RVRYALVREEGEERPDVSLYAESRPLSVVRSVDIDDVGAVKATLRTAKGGSPP 896



 Score =  170 bits (413), Expect = 5e-40
 Identities = 141/489 (28%), Positives = 212/489 (43%), Gaps = 33/489 (6%)

Query: 90  FRIDGRSGALLTRASLDREKVARYT---VLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146
           FR+D  SG L    +LDRE++  ++    L+      +PV           V + D ND+
Sbjct: 433 FRLDPHSGVLTVTETLDRERICPHSESCALLFKLFFENPVQ-----LIRGEVEVRDVNDH 487

Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206
            P F +K   + V E  S       +   A D DVG N    Y++   N     +++   
Sbjct: 488 SPVFPQKEVVLEVLETASPGSR--FSLESAQDEDVGINGLQNYSL-SPNPYFSLALEKWK 544

Query: 207 GDVSLVKT-----LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261
           G    VK      LD E+ R   LV+ A DGGSP RS T Q+ + + D NDN P F   +
Sbjct: 545 GGAEFVKLVLQKPLDREEQRELHLVLTATDGGSPPRSGTAQVRVVVLDANDNMPVFSREV 604

Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321
           ++  V+EN P G  +VRV A D DEG N ++ YT T  + +        ++P +G +  S
Sbjct: 605 YEVRVAENSPPGQLVVRVSAADPDEGSNGKVRYTFT--EMSEQSQQLYELNPETGEIRVS 662

Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381
           G LD E +  ++L+V A DGG    SA                          + ED PP
Sbjct: 663 GNLDYEEEKMHELVVRAMDGGG--LSAHCRVHVEVLDVNDNAPEIALSSVSASIPEDAPP 720

Query: 382 GTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGL-ITVAQPLDFKQERRYV 438
            T V  L+  D D  ++ R    I G      FS+T+       +  +  LD +    Y 
Sbjct: 721 RTVVALLSVRDRDSGDNGRTECAIEGDVP---FSLTAAFANHYELRTSAALDRETTAEYN 777

Query: 439 LTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496
           +++ ATD G    S    V + I D N+ AP F  A Y+ SV E+      +  V ATD+
Sbjct: 778 VSIVATDWGRARLSARESVSVRIADVNDNAPRFTQAAYSMSVSENEAGAVRIGSVKATDA 837

Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556
           D G N ++ Y+L  E   E          +  ++  ++  + +D + +     T+    G
Sbjct: 838 DAGANGRVRYALVREEGEER-----PDVSLYAESRPLSVVRSVDIDDVGAVKATLRTAKG 892

Query: 557 GVPSLSDTT 565
           G P  S  T
Sbjct: 893 GSPPRSAAT 901



 Score =  158 bits (384), Expect = 2e-36
 Identities = 116/374 (31%), Positives = 177/374 (47%), Gaps = 20/374 (5%)

Query: 456 QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515
           ++ + D N+++PVF        V E A  G+   + SA D DVGIN    YSLS    N 
Sbjct: 478 EVEVRDVNDHSPVFPQKEVVLEVLETASPGSRFSLESAQDEDVGINGLQNYSLSP---NP 534

Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575
             +   +++    +   +   K LDRE      L +TA DGG P  S T  V + V+D N
Sbjct: 535 YFSLALEKWKGGAEFVKLVLQKPLDREEQRELHLVLTATDGGSPPRSGTAQVRVVVLDAN 594

Query: 576 DNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFVIDP 634
           DN PVF +++Y   + E++  G  V +V A D D G NG++ Y   +  ++ +  + ++P
Sbjct: 595 DNMPVFSREVYEVRVAENSPPGQLVVRVSAADPDEGSNGKVRYTFTEMSEQSQQLYELNP 654

Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694
            +G IR +  LD E    H+L   A+DGG    S+   VH+++ D+ND+ P      ++ 
Sbjct: 655 ETGEIRVSGNLDYEEEKMHELVVRAMDGGG--LSAHCRVHVEVLDVNDNAPEIALSSVSA 712

Query: 695 YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDL 754
            I E++P  T +  +   D D G N     +I+G      FSL T   ++  EL T   L
Sbjct: 713 SIPEDAPPRTVVALLSVRDRDSGDNGRTECAIEG---DVPFSL-TAAFANHYELRTSAAL 768

Query: 755 DYESPRKKYELVIRAASPPLWNDVR------VEILVTDVNDNAPVMKDFQIIFNNYKDCF 808
           D E+  + Y + I A     W   R      V + + DVNDNAP         +  ++  
Sbjct: 769 DRETTAE-YNVSIVATD---WGRARLSARESVSVRIADVNDNAPRFTQAAYSMSVSENEA 824

Query: 809 PVGPFGRVPAYDAD 822
                G V A DAD
Sbjct: 825 GAVRIGSVKATDAD 838



 Score =  155 bits (376), Expect = 2e-35
 Identities = 117/416 (28%), Positives = 189/416 (45%), Gaps = 39/416 (9%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           I  ++ V D NDHSPVF  ++    V E AS G+      A D+D+G N    Y++    
Sbjct: 475 IRGEVEVRDVNDHSPVFPQKEVVLEVLETASPGSRFSLESAQDEDVGINGLQNYSL---- 530

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
             + NP               + ++       L+ +  LDRE+     +++ ATD  SP 
Sbjct: 531 --SPNP---------YFSLALEKWKGGAEFVKLVLQKPLDREEQRELHLVLTATDGGSPP 579

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
               S TA + V ++D NDN P FS + Y V V E  +     ++ ++ A D D G+N  
Sbjct: 580 R---SGTAQVRVVVLDANDNMPVFSREVYEVRVAE--NSPPGQLVVRVSAADPDEGSNGK 634

Query: 187 IRYAI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
           +RY    +   +Q  + ++  +G++ +   LDYE+ + + LV+RA DGG  S     ++ 
Sbjct: 635 VRYTFTEMSEQSQQLYELNPETGEIRVSGNLDYEEEKMHELVVRAMDGGGLSAH--CRVH 692

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           + + DVNDNAP    S    S+ E+ P    +  +   D D G N       T+    G+
Sbjct: 693 VEVLDVNDNAPEIALSSVSASIPEDAPPRTVVALLSVRDRDSGDNGR-----TECAIEGD 747

Query: 305 VDLPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
           V   +T    + + + TS  LDRET A+Y + + ATD G    SA  +            
Sbjct: 748 VPFSLTAAFANHYELRTSAALDRETTAEYNVSIVATDWGRARLSARESVSVRIADVNDNA 807

Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG 419
             F    Y + ++E+E     + ++ ATDAD          G N R R+++  + G
Sbjct: 808 PRFTQAAYSMSVSENEAGAVRIGSVKATDAD---------AGANGRVRYALVREEG 854



 Score =  135 bits (326), Expect = 2e-29
 Identities = 103/342 (30%), Positives = 158/342 (46%), Gaps = 32/342 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ VLD ND+ PVF  + YE  V E +  G  V+ + A D D G N +V YT   ++  +
Sbjct: 587 RVVVLDANDNMPVFSREVYEVRVAENSPPGQLVVRVSAADPDEGSNGKVRYTFTEMSEQS 646

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                            Q ++ ++  +G +    +LD E+   + ++V+A D        
Sbjct: 647 -----------------QQLYELNPETGEIRVSGNLDYEEEKMHELVVRAMDGGG----- 684

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           LS+   +HV ++D NDN P+ +  + + S+ ED       V+A +   D D G N     
Sbjct: 685 LSAHCRVHVEVLDVNDNAPEIALSSVSASIPED--APPRTVVALLSVRDRDSGDNGRTEC 742

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           AI G    + FS+ +   +   ++T   LD E    Y + I A D G    S    + + 
Sbjct: 743 AIEG---DVPFSLTAAFANHYELRTSAALDRETTAEYNVSIVATDWGRARLSARESVSVR 799

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
           I DVNDNAPRF  + +  SVSEN      I  V+A DAD G N  + Y +  ++     D
Sbjct: 800 IADVNDNAPRFTQAAYSMSVSENEAGAVRIGSVKATDADAGANGRVRYALVREEGEERPD 859

Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348
           + +  + R   V  S  +D +  A    L TA  GG PPRSA
Sbjct: 860 VSLYAESRPLSVVRSVDID-DVGAVKATLRTA-KGGSPPRSA 899



 Score = 81.4 bits (192), Expect = 3e-13
 Identities = 81/285 (28%), Positives = 125/285 (43%), Gaps = 16/285 (5%)

Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGS---FVIDPASGVIRTNKALDRESVATHDLK- 656
           S VG    D+GL+         +   EGS   F +DP SGV+   + LDRE +  H    
Sbjct: 401 SLVGNVAQDLGLSPSQLAARKARVVSEGSEQHFRLDPHSGVLTVTETLDRERICPHSESC 460

Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
           A+            +   +++ D+ND  PVF    +   + E +  G+      A D D 
Sbjct: 461 ALLFKLFFENPVQLIRGEVEVRDVNDHSPVFPQKEVVLEVLETASPGSRFSLESAQDEDV 520

Query: 717 GPNAVVHYSIKGGDDSNSFSLET-RQGSDKAELVTMVDLDYESPRKKYELVIRAA---SP 772
           G N + +YS+   +   S +LE  + G++  +LV    LD E  R+ + LV+ A    SP
Sbjct: 521 GINGLQNYSLSP-NPYFSLALEKWKGGAEFVKLVLQKPLDREEQRELH-LVLTATDGGSP 578

Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDAD--VTDKLQY 829
           P     +V ++V D NDN PV    ++      +  P G    RV A D D     K++Y
Sbjct: 579 PRSGTAQVRVVVLDANDNMPVFSR-EVYEVRVAENSPPGQLVVRVSAADPDEGSNGKVRY 637

Query: 830 RI--LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
               +S  +  L  LN  TG + +S  L+    K+  + V   DG
Sbjct: 638 TFTEMSEQSQQLYELNPETGEIRVSGNLDYEEEKMHELVVRAMDG 682


>UniRef50_UPI00015B46FC Cluster: PREDICTED: similar to CG14900-PA;
            n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
            CG14900-PA - Nasonia vitripennis
          Length = 2225

 Score =  202 bits (494), Expect = 8e-50
 Identities = 212/823 (25%), Positives = 365/823 (44%), Gaps = 92/823 (11%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-LKATDQDIGK--NAEVEYTIELVTA 67
            + V D NDH+P F    Y  +V E   +G T+   + A D+D     N++V Y I     
Sbjct: 370  VYVEDVNDHAPQFVDAPYHVTVDELTPTGLTIFRGIHAFDKDKPNTPNSDVHYAI----- 424

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRID-GRSGALLTRASLDREKVAR-YTVLVKATDQASP 125
                               Q  F ++ G   AL+ R  LD +   R Y +++ A D+ +P
Sbjct: 425  --------------IKGNEQGKFSLESGHRTALILRKPLDYDIGDREYVLIISANDRGTP 470

Query: 126  VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV------IAKIKATDA 179
                 S+  TI + ++D++D  P+F+++ Y   + E   +  +P+         I+A D 
Sbjct: 471  PK---STNTTITITVVDNDDLDPKFTQEVYRTEIFEFYPMPSHPIHKEIEFATPIRAIDQ 527

Query: 180  DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-----YRLVIRAQDGGS 234
            D   +  + Y II GN +  F +D  +G + L + +D +  R+     + L I A    +
Sbjct: 528  DRDIDVPVLYDIISGNERGLFHLDPRNGTLFLDRAIDLDAERNLPGNTFVLQIHASQIDN 587

Query: 235  PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294
            P +  + ++ + + D+NDN P F    +  S+ EN+P G+S+++V AYD D+GVN E TY
Sbjct: 588  PLKVASARVEVEVLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVIAYDRDQGVNGEFTY 647

Query: 295  TMTDKDYTGNVDLPITIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGGDP-----PRS 347
             + D   +G      ++DP SGW+    Q  LDRE ++  Q+ V A +           S
Sbjct: 648  ELNDP--SG----AFSVDPISGWLTVQDQSVLDREQKSFLQMKVLAVEKQPSVVKPYNGS 701

Query: 348  ATATXXXXXXXXXXXXXXFMPGQ-YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEI- 403
            ++                F+PG   E+    D   GT +  + A D D   +  + Y++ 
Sbjct: 702  SSVEVEVTLLDANDNNPVFVPGNLLELVAQSDFKVGTILGQVHAVDNDLGTNGLVRYKLQ 761

Query: 404  TGGNTRGRFSITSQNGRGLITVA-QPLDFKQERRYVLTVSATD-----SGGRSDTAMVQI 457
              GN  G+      +  G+ITVA  P+    E R+ + + A D     S  R   A+V I
Sbjct: 762  RPGNFTGKMPFAVNSDTGVITVADSPI---LEGRHAIFIEAADQPANPSERRFSLAVVTI 818

Query: 458  NI-TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA 516
            ++     + AP F  APY   V  + P+GT+V  +   ++  G   ++ Y L        
Sbjct: 819  DVFRPEGSKAPDFIGAPYEFWVGANVPVGTSVGQIRVNEAVNG--NEVVYDLLHSY---- 872

Query: 517  VAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVND 576
              H    F +  ++G IT    ++R   S Y       +    SLS  T+V I VVD ND
Sbjct: 873  --HEGVPFAVEERSGTITVVDEIERYKQSSYDFEAVVTN--EKSLSLVTNVSIHVVDPND 928

Query: 577  NEPVFKQQLYTANI---MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633
               +F +    A +   + +   G  +  V   +A   L   +H+ +   ++++ + +  
Sbjct: 929  ESGIFAKGTTKAPLVFHVRENAAGAFIGHVVPANASDSLK-NVHFLI--ANQQDVAEIAI 985

Query: 634  PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693
              +GV+ T   L+RE    + L A+A    +P       V I ++D +D+ P+F +    
Sbjct: 986  TDTGVLYTPTGLNREKRQNYSLTAIA---ESPRGVGVFQVMIIVDDEDDNAPIFSASAYE 1042

Query: 694  FYISENSPIGTTI---GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750
              ISENS  GT +     + A DPDE  + +  ++++ G+ S+ F ++   G     +  
Sbjct: 1043 GRISENSQTGTEVIMTNHVSARDPDEDSSFM--FTLR-GEGSDLFRIDRNTGR-VFFIGN 1098

Query: 751  MVDLDYESPRKKYEL-VIRAASPPLWNDVRVEILVTDVNDNAP 792
              +L     +  Y L ++        ++V + I V D NDN P
Sbjct: 1099 ATELLDREEKPLYNLQIVAGERKKKSSNVSLTIHVDDENDNPP 1141



 Score =  171 bits (417), Expect = 2e-40
 Identities = 167/606 (27%), Positives = 266/606 (43%), Gaps = 56/606 (9%)

Query: 223 YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR-VQA 281
           +RL     DG     S+   + + + DVND+AP+F  + +  +V E  P G +I R + A
Sbjct: 348 FRLGCDYSDGSDSLVSSHLSVTVYVEDVNDHAPQFVDAPYHVTVDELTPTGLTIFRGIHA 407

Query: 282 YDADE--GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET-QAKYQLLVTA 338
           +D D+    N+++ Y +   +  G   L      R+  +     LD +    +Y L+++A
Sbjct: 408 FDKDKPNTPNSDVHYAIIKGNEQGKFSL--ESGHRTALILRK-PLDYDIGDREYVLIISA 464

Query: 339 TDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP-PGTPV-------VTLTA 390
            D G PP+S   T              F    Y  E+ E  P P  P+         + A
Sbjct: 465 NDRGTPPKSTNTTITITVVDNDDLDPKFTQEVYRTEIFEFYPMPSHPIHKEIEFATPIRA 524

Query: 391 TDADEDNRLH--YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE---RRYVLTVSAT- 444
            D D D  +   Y+I  GN RG F +  +NG   +  A  LD ++      +VL + A+ 
Sbjct: 525 IDQDRDIDVPVLYDIISGNERGLFHLDPRNGTLFLDRAIDLDAERNLPGNTFVLQIHASQ 584

Query: 445 -DSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503
            D+  +  +A V++ + D N+  P FE   Y  S+ E+ P G +VL V A D D G+N +
Sbjct: 585 IDNPLKVASARVEVEVLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVIAYDRDQGVNGE 644

Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITT--NKLLDRETMSGYLLTVTARDGGVPSL 561
            TY L+              F ++P +G +T     +LDRE  S   + V A +   PS+
Sbjct: 645 FTYELNDP---------SGAFSVDPISGWLTVQDQSVLDREQKSFLQMKVLAVE-KQPSV 694

Query: 562 ------SDTTDVEISVVDVNDNEPVF-KQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614
                 S + +VE++++D NDN PVF    L       D  VGT + QV A D D+G NG
Sbjct: 695 VKPYNGSSSVEVEVTLLDANDNNPVFVPGNLLELVAQSDFKVGTILGQVHAVDNDLGTNG 754

Query: 615 RIHYELDPKDREEGS--FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS---S 669
            + Y+L       G   F ++  +GVI    +   E    H +   A D    P     S
Sbjct: 755 LVRYKLQRPGNFTGKMPFAVNSDTGVITVADSPILE--GRHAIFIEAADQPANPSERRFS 812

Query: 670 TVIVHIKI-EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
             +V I +        P F      F++  N P+GT++G+IR ++   G N VV+  +  
Sbjct: 813 LAVVTIDVFRPEGSKAPDFIGAPYEFWVGANVPVGTSVGQIRVNEAVNG-NEVVYDLLHS 871

Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL-VIRAASPPLWNDVRVEILVTDV 787
             +   F++E R G+     +T+VD      +  Y+   +      L     V I V D 
Sbjct: 872 YHEGVPFAVEERSGT-----ITVVDEIERYKQSSYDFEAVVTNEKSLSLVTNVSIHVVDP 926

Query: 788 NDNAPV 793
           ND + +
Sbjct: 927 NDESGI 932



 Score =  169 bits (412), Expect = 7e-40
 Identities = 196/760 (25%), Positives = 321/760 (42%), Gaps = 65/760 (8%)

Query: 127  SDRL-SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV--GA 183
            SD L SS  ++ V + D ND+ PQF +  Y V+VDE ++ T   +   I A D D     
Sbjct: 358  SDSLVSSHLSVTVYVEDVNDHAPQFVDAPYHVTVDE-LTPTGLTIFRGIHAFDKDKPNTP 416

Query: 184  NSAIRYAIIGGNTQMQFSIDSLSGDVSLV-KTLDYE-QVRSYRLVIRAQDGGSPSRSNTT 241
            NS + YAII GN Q +FS++S      ++ K LDY+   R Y L+I A D G+P +S  T
Sbjct: 417  NSDVHYAIIKGNEQGKFSLESGHRTALILRKPLDYDIGDREYVLIISANDRGTPPKSTNT 476

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR--------VQAYDADEGVNAELT 293
             + I + D +D  P+F   +++  + E  P+    +         ++A D D  ++  + 
Sbjct: 477  TITITVVDNDDLDPKFTQEVYRTEIFEFYPMPSHPIHKEIEFATPIRAIDQDRDIDVPVL 536

Query: 294  YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK-----YQLLVTATDGGDPPRSA 348
            Y +     +GN      +DPR+G ++    +D + +       + L + A+   +P + A
Sbjct: 537  YDI----ISGNERGLFHLDPRNGTLFLDRAIDLDAERNLPGNTFVLQIHASQIDNPLKVA 592

Query: 349  TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT 408
            +A               F    Y + + E+ P G  V+ + A D D+     +     + 
Sbjct: 593  SARVEVEVLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVIAYDRDQGVNGEFTYELNDP 652

Query: 409  RGRFSITSQNGRGLITVAQPLDFKQE---RRYVLTV----SATDSGGRSDTAMVQINITD 461
             G FS+   +G   +     LD +Q+   +  VL V    S       S +  V++ + D
Sbjct: 653  SGAFSVDPISGWLTVQDQSVLDREQKSFLQMKVLAVEKQPSVVKPYNGSSSVEVEVTLLD 712

Query: 462  ANNYAPVFENAPYTASVFE-DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520
            AN+  PVF        V + D  +GT +  V A D+D+G N  + Y L    +       
Sbjct: 713  ANDNNPVFVPGNLLELVAQSDFKVGTILGQVHAVDNDLGTNGLVRYKLQRPGNFTG---- 768

Query: 521  DQQFVINPQTGAITTNKLLDRETMSG-YLLTVTARDGGVPSLSDTTDVEISVVDV----N 575
               F +N  TG IT   + D   + G + + + A D           + +  +DV     
Sbjct: 769  KMPFAVNSDTGVIT---VADSPILEGRHAIFIEAADQPANPSERRFSLAVVTIDVFRPEG 825

Query: 576  DNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA 635
               P F    Y   +  +  VGTSV Q+   +A  G    + Y+L     E   F ++  
Sbjct: 826  SKAPDFIGAPYEFWVGANVPVGTSVGQIRVNEAVNG--NEVVYDLLHSYHEGVPFAVEER 883

Query: 636  SGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC---- 691
            SG I     ++R   +++D +AV  +  +    + V +H  + D ND   +F        
Sbjct: 884  SGTITVVDEIERYKQSSYDFEAVVTNEKSLSLVTNVSIH--VVDPNDESGIFAKGTTKAP 941

Query: 692  LTFYISENSPIGTTIGE-IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750
            L F++ EN+  G  IG  + A+  D   N  VH+ I    D    ++     +D   L T
Sbjct: 942  LVFHVRENA-AGAFIGHVVPANASDSLKN--VHFLIANQQDVAEIAI-----TDTGVLYT 993

Query: 751  MVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQI---IFNNYKDC 807
               L+ E  R+ Y L   A SP      +V I+V D +DNAP+         I  N +  
Sbjct: 994  PTGLNREK-RQNYSLTAIAESPRGVGVFQVMIIVDDEDDNAPIFSASAYEGRISENSQTG 1052

Query: 808  FPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTG 847
              V     V A D D      +  L G  ++L  ++  TG
Sbjct: 1053 TEVIMTNHVSARDPDEDSSFMF-TLRGEGSDLFRIDRNTG 1091



 Score =  153 bits (372), Expect = 5e-35
 Identities = 159/600 (26%), Positives = 243/600 (40%), Gaps = 77/600 (12%)

Query: 32   VREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFR 91
            V E  + G  ++ L A D D GKNAE+ Y I       +    +          V+  F 
Sbjct: 1185 VPENVTIGIPIIRLVARDPDDGKNAEITYNI----LSEIGGRTSFDSKTKSSSVVKRYFV 1240

Query: 92   IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151
            +D RSG +    +L  E      + + A D        L    TI V+  D ND+ P F 
Sbjct: 1241 MDSRSGEISVAGALPAE--TDIVLEIAARDHGG-----LMDNVTIRVHAFDVNDHAPVFK 1293

Query: 152  EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN--TQMQFSIDSLSGDV 209
            +  Y   V E         + + +ATDAD G N+ I Y ++  N    ++F +    G  
Sbjct: 1294 QSWYLFDVPEGNFKRFE--MGRFEATDADFGDNANITYELVPTNLDNSVKFEVSRYQGTF 1351

Query: 210  SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY----------- 258
            SL   LD E    Y   + A+DGG    S++  + I+++DVNDN PRFY           
Sbjct: 1352 SLGGNLDRETRDLYNFKVIAKDGGKIKMSSSVDIEIHVQDVNDNPPRFYGFQEMGRLPSN 1411

Query: 259  -------------TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
                           ++  SV EN  +G  + ++ A D+D   N             G +
Sbjct: 1412 LVDVYRKDSKQVLVPIYYASVPENSQVGTIVTKIHANDSDFAGNGNGVILFDIPHVRGQM 1471

Query: 306  DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX---- 361
                +ID + G V T G LD ETQ  + L + A+D G P  ++TA               
Sbjct: 1472 QY-FSIDNKEGLVTTVGNLDYETQNVHNLTIVASDLGSPSLTSTALLIVRILDVDEGPDE 1530

Query: 362  -XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEI--TGGNTRGRFSITSQN 418
                 F    YEVE+ E+ P    ++ L  +D ++D ++ Y I    G+ R  FS+  +N
Sbjct: 1531 PKRPVFQHRYYEVEVEENSPVPMRILDLNVSDNNKDEQIRYSIILDEGDGREHFSLDPKN 1590

Query: 419  GRGLITVAQPLDFKQERRYVLTVSA----TDSG---------GR------SDTAMVQINI 459
            G  L  +  P D +   RY L V      T  G         G+       + A + + +
Sbjct: 1591 G-SLFLLTSP-DREVRDRYELKVRVDKVKTSRGMPVMIYPVVGKRLNGLGPNEAKIILKV 1648

Query: 460  TDANNYAPVFE--NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517
             D N+ AP F+    P  A +   A  G  V+ V A D D G N Q+ Y +      ++ 
Sbjct: 1649 KDVNDNAPRFKTNGRPILAVLPTSAYYGYNVIKVEAEDPDEGANGQVRYQILGGREQDS- 1707

Query: 518  AHHDQQFVINPQTGAITT--NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575
                 +F I+P +G +    N   D   + G+ +  T R G     S   +V + V+D N
Sbjct: 1708 ----PKFAIDPVSGQVQAAGNFARDAGRVFGFDVKATDRAGAEDGRSSIANVFVYVLDDN 1763



 Score =  148 bits (359), Expect = 2e-33
 Identities = 217/908 (23%), Positives = 366/908 (40%), Gaps = 103/908 (11%)

Query: 57   EVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRA-SLDREKVARYT 114
            E+E+   +   D     D            + +F +D R+G L L RA  LD E+     
Sbjct: 515  EIEFATPIRAIDQDRDIDVPVLYDIISGNERGLFHLDPRNGTLFLDRAIDLDAERNLPGN 574

Query: 115  VLVKATDQASPVSDRLS-STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK 173
              V     AS + + L  ++A + V ++D NDN P+F    Y +S+ E++   +   + +
Sbjct: 575  TFVLQI-HASQIDNPLKVASARVEVEVLDLNDNLPEFEVDFYNISIVENLP--NGFSVLQ 631

Query: 174  IKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLV--KTLDYEQVRSYRLVIRAQD 231
            + A D D G N    Y +   +    FS+D +SG +++     LD EQ    ++ + A +
Sbjct: 632  VIAYDRDQGVNGEFTYEL--NDPSGAFSVDPISGWLTVQDQSVLDREQKSFLQMKVLAVE 689

Query: 232  GGSPS------RSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN-VPIGYSIVRVQAYDA 284
               PS       S++ ++ + + D NDN P F      E V+++   +G  + +V A D 
Sbjct: 690  K-QPSVVKPYNGSSSVEVEVTLLDANDNNPVFVPGNLLELVAQSDFKVGTILGQVHAVDN 748

Query: 285  DEGVNAELTYTMTDK-DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD 343
            D G N  + Y +    ++TG   +P  ++  +G +  +     E   ++ + + A D   
Sbjct: 749  DLGTNGLVRYKLQRPGNFTGK--MPFAVNSDTGVITVADSPILE--GRHAIFIEAADQPA 804

Query: 344  PPR----SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRL 399
             P     S                  F+   YE  +  + P GT V  +   +A   N +
Sbjct: 805  NPSERRFSLAVVTIDVFRPEGSKAPDFIGAPYEFWVGANVPVGTSVGQIRVNEAVNGNEV 864

Query: 400  HYEITGGNTRG-RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN 458
             Y++      G  F++  ++G   ITV   ++  ++  Y      T+    S    V I+
Sbjct: 865  VYDLLHSYHEGVPFAVEERSGT--ITVVDEIERYKQSSYDFEAVVTNEKSLSLVTNVSIH 922

Query: 459  ITDANNYAPVFEN----APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
            + D N+ + +F      AP    V E+A       VV A  SD   N     +   +++ 
Sbjct: 923  VVDPNDESGIFAKGTTKAPLVFHVRENAAGAFIGHVVPANASDSLKNVHFLIANQQDVAE 982

Query: 515  EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
             A+            TG + T   L+RE    Y LT  A     P       V I V D 
Sbjct: 983  IAIT----------DTGVLYTPTGLNREKRQNYSLTAIAES---PRGVGVFQVMIIVDDE 1029

Query: 575  NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA-DVGLNGRIHYELDPKDREEGS--FV 631
            +DN P+F    Y   I E++  GT V       A D   +    + L    R EGS  F 
Sbjct: 1030 DDNAPIFSASAYEGRISENSQTGTEVIMTNHVSARDPDEDSSFMFTL----RGEGSDLFR 1085

Query: 632  IDPASGVI----RTNKALDRESVATHDLKAVA---------------ID--GGTPPQSST 670
            ID  +G +       + LDRE    ++L+ VA               +D     PP    
Sbjct: 1086 IDRNTGRVFFIGNATELLDREEKPLYNLQIVAGERKKKSSNVSLTIHVDDENDNPPSFVQ 1145

Query: 671  VIV----HIKI-EDINDSPP-------VFESDCLT--FYISENSPIGTTIGEIRAHDPDE 716
            +++     I++ +D  D  P       V  SD  +   Y+ EN  IG  I  + A DPD+
Sbjct: 1146 MVILPDQGIRVSKDKTDKDPAPTQLTSVTNSDYRSPLLYVPENVTIGIPIIRLVARDPDD 1205

Query: 717  GPNAVVHYSIKGG-DDSNSFSLETRQGSDKAELVTMVDLDYE-----SPRKKYELVIRAA 770
            G NA + Y+I        SF  +T+  S       M     E     +   + ++V+  A
Sbjct: 1206 GKNAEITYNILSEIGGRTSFDSKTKSSSVVKRYFVMDSRSGEISVAGALPAETDIVLEIA 1265

Query: 771  SPP---LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD-- 825
            +     L ++V + +   DVND+APV K    +F+  +  F     GR  A DAD  D  
Sbjct: 1266 ARDHGGLMDNVTIRVHAFDVNDHAPVFKQSWYLFDVPEGNFKRFEMGRFEATDADFGDNA 1325

Query: 826  KLQYRILSGNNANLIL--LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLS 883
             + Y ++  N  N +   ++   G+ +L   L+     L   +V   DG  +IK    + 
Sbjct: 1326 NITYELVPTNLDNSVKFEVSRYQGTFSLGGNLDRETRDLYNFKVIAKDG-GKIKMSSSVD 1384

Query: 884  VRLITEEM 891
            + +  +++
Sbjct: 1385 IEIHVQDV 1392



 Score =  147 bits (355), Expect = 6e-33
 Identities = 130/421 (30%), Positives = 196/421 (46%), Gaps = 53/421 (12%)

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
            G I+VA  L    E   VL ++A D GG  D   ++++  D N++APVF+ + Y   V E
Sbjct: 1246 GEISVAGALP--AETDIVLEIAARDHGGLMDNVTIRVHAFDVNDHAPVFKQSWYLFDVPE 1303

Query: 481  DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
                   +    ATD+D G NA ITY L     + +V     +F ++   G  +    LD
Sbjct: 1304 GNFKRFEMGRFEATDADFGDNANITYELVPTNLDNSV-----KFEVSRYQGTFSLGGNLD 1358

Query: 541  RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF------------------- 581
            RET   Y   V A+DGG   +S + D+EI V DVNDN P F                   
Sbjct: 1359 RETRDLYNFKVIAKDGGKIKMSSSVDIEIHVQDVNDNPPRFYGFQEMGRLPSNLVDVYRK 1418

Query: 582  --KQQL---YTANIMEDALVGTSVSQVGATDADVGLNGR--IHYELDPKDREEGSFVIDP 634
              KQ L   Y A++ E++ VGT V+++ A D+D   NG   I +++     +   F ID 
Sbjct: 1419 DSKQVLVPIYYASVPENSQVGTIVTKIHANDSDFAGNGNGVILFDIPHVRGQMQYFSIDN 1478

Query: 635  ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP-----PVFES 689
              G++ T   LD E+   H+L  VA D G+P  +ST ++ ++I D+++ P     PVF+ 
Sbjct: 1479 KEGLVTTVGNLDYETQNVHNLTIVASDLGSPSLTSTALLIVRILDVDEGPDEPKRPVFQH 1538

Query: 690  DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS------ 743
                  + ENSP+   I ++   D ++         +  GD    FSL+ + GS      
Sbjct: 1539 RYYEVEVEENSPVPMRILDLNVSDNNKDEQIRYSIILDEGDGREHFSLDPKNGSLFLLTS 1598

Query: 744  ------DKAELVTMVDLDYES---PRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVM 794
                  D+ EL   VD    S   P   Y +V +  +    N+ ++ + V DVNDNAP  
Sbjct: 1599 PDREVRDRYELKVRVDKVKTSRGMPVMIYPVVGKRLNGLGPNEAKIILKVKDVNDNAPRF 1658

Query: 795  K 795
            K
Sbjct: 1659 K 1659



 Score =  142 bits (344), Expect = 1e-31
 Identities = 207/856 (24%), Positives = 339/856 (39%), Gaps = 116/856 (13%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++ VLD ND+ P FE+  Y  S+ E   +G +VL + A D+D G N E  Y +       
Sbjct: 597  EVEVLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVIAYDRDQGVNGEFTYELN------ 650

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR--ASLDREKVARYTVLVKATDQASPVS 127
             +P  A              F +D  SG L  +  + LDRE+ +   + V A ++   V 
Sbjct: 651  -DPSGA--------------FSVDPISGWLTVQDQSVLDREQKSFLQMKVLAVEKQPSVV 695

Query: 128  DRL--SSTATIHVNIIDDNDNYPQFSEKTYTVSVDE-DISVTDNPVIAKIKATDADVGAN 184
                 SS+  + V ++D NDN P F        V + D  V    ++ ++ A D D+G N
Sbjct: 696  KPYNGSSSVEVEVTLLDANDNNPVFVPGNLLELVAQSDFKV--GTILGQVHAVDNDLGTN 753

Query: 185  SAIRYAIIG-GNT--QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
              +RY +   GN   +M F+++S +G +++  +   E  R    +  A    +PS    +
Sbjct: 754  GLVRYKLQRPGNFTGKMPFAVNSDTGVITVADSPILEG-RHAIFIEAADQPANPSERRFS 812

Query: 242  QLLINI---RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
              ++ I   R     AP F  + ++  V  NVP+G S+ +++  +A  G   E+ Y +  
Sbjct: 813  LAVVTIDVFRPEGSKAPDFIGAPYEFWVGANVPVGTSVGQIRVNEAVNG--NEVVYDLLH 870

Query: 299  KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358
              + G   +P  ++ RSG +    +++R  Q+ Y      T+  +   S           
Sbjct: 871  SYHEG---VPFAVEERSGTITVVDEIERYKQSSYDFEAVVTN--EKSLSLVTNVSIHVVD 925

Query: 359  XXXXXXXFMPGQYEVELA---EDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSI 414
                   F  G  +  L     +   G  +  +   +A +    +H+ I         +I
Sbjct: 926  PNDESGIFAKGTTKAPLVFHVRENAAGAFIGHVVPANASDSLKNVHFLIANQQDVAEIAI 985

Query: 415  TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPY 474
            T     G++     L+ ++ + Y LT  A    G      V I + D ++ AP+F  + Y
Sbjct: 986  TDT---GVLYTPTGLNREKRQNYSLTAIAESPRGVG-VFQVMIIVDDEDDNAPIFSASAY 1041

Query: 475  TASVFEDAPIGTTVLV---VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
               + E++  GT V++   VSA D D   ++   ++L  E S+         F I+  TG
Sbjct: 1042 EGRISENSQTGTEVIMTNHVSARDPDE--DSSFMFTLRGEGSD--------LFRIDRNTG 1091

Query: 532  AI----TTNKLLDRETMSGYLLTVTARDGGVPS--------LSDTTDVEISVV------- 572
             +       +LLDRE    Y L + A +    S        + D  D   S V       
Sbjct: 1092 RVFFIGNATELLDREEKPLYNLQIVAGERKKKSSNVSLTIHVDDENDNPPSFVQMVILPD 1151

Query: 573  -------DVNDNEPVFKQQLYTAN---------IMEDALVGTSVSQVGATDADVGLNGRI 616
                   D  D +P   Q     N         + E+  +G  + ++ A D D G N  I
Sbjct: 1152 QGIRVSKDKTDKDPAPTQLTSVTNSDYRSPLLYVPENVTIGIPIIRLVARDPDDGKNAEI 1211

Query: 617  HYEL----------DPKDREEGS----FVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
             Y +          D K +        FV+D  SG I    AL  E+     L+  A D 
Sbjct: 1212 TYNILSEIGGRTSFDSKTKSSSVVKRYFVMDSRSGEISVAGALPAETDIV--LEIAARDH 1269

Query: 663  GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722
            G    + T+ VH    D+ND  PVF+     F + E +     +G   A D D G NA +
Sbjct: 1270 GGLMDNVTIRVHAF--DVNDHAPVFKQSWYLFDVPEGNFKRFEMGRFEATDADFGDNANI 1327

Query: 723  HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEI 782
             Y +   +  NS   E  +      L   +D +         +        + + V +EI
Sbjct: 1328 TYELVPTNLDNSVKFEVSRYQGTFSLGGNLDRETRDLYNFKVIAKDGGKIKMSSSVDIEI 1387

Query: 783  LVTDVNDNAPVMKDFQ 798
             V DVNDN P    FQ
Sbjct: 1388 HVQDVNDNPPRFYGFQ 1403



 Score =  126 bits (305), Expect = 7e-27
 Identities = 191/777 (24%), Positives = 305/777 (39%), Gaps = 118/777 (15%)

Query: 71   NPEDAXXXXXXXXXXVQDVFRID-GRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            N  D+           QDV  I    +G L T   L+REK   Y++   A       S R
Sbjct: 962  NASDSLKNVHFLIANQQDVAEIAITDTGVLYTPTGLNREKRQNYSLTAIAE------SPR 1015

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
                  + + + D++DN P FS   Y   + E+ S T   VI     +  D   +S+  +
Sbjct: 1016 GVGVFQVMIIVDDEDDNAPIFSASAYEGRISEN-SQTGTEVIMTNHVSARDPDEDSSFMF 1074

Query: 190  AIIGGNTQMQFSIDSLSGDVSLV----KTLDYEQVRSYR----------------LVIRA 229
             + G  + + F ID  +G V  +    + LD E+   Y                 L I  
Sbjct: 1075 TLRGEGSDL-FRIDRNTGRVFFIGNATELLDREEKPLYNLQIVAGERKKKSSNVSLTIHV 1133

Query: 230  QDGGSPSRSNTTQLLINIRDVN--------DNAPRFYTSLFQES-------VSENVPIGY 274
             D      S    +++  + +         D AP   TS+           V ENV IG 
Sbjct: 1134 DDENDNPPSFVQMVILPDQGIRVSKDKTDKDPAPTQLTSVTNSDYRSPLLYVPENVTIGI 1193

Query: 275  SIVRVQAYDADEGVNAELTYTMTDK-----------DYTGNVDLPITIDPRSGWVYTSGQ 323
             I+R+ A D D+G NAE+TY +  +             +  V     +D RSG +  +G 
Sbjct: 1194 PIIRLVARDPDDGKNAEITYNILSEIGGRTSFDSKTKSSSVVKRYFVMDSRSGEISVAGA 1253

Query: 324  LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383
            L  ET    +  + A D G        T              F    Y  ++ E      
Sbjct: 1254 LPAETDIVLE--IAARDHGG--LMDNVTIRVHAFDVNDHAPVFKQSWYLFDVPEGNFKRF 1309

Query: 384  PVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441
             +    ATDAD  ++  + YE+   N            +G  ++   LD +    Y   V
Sbjct: 1310 EMGRFEATDADFGDNANITYELVPTNLDNSVKFEVSRYQGTFSLGGNLDRETRDLYNFKV 1369

Query: 442  SATDSGG--RSDTAMVQINITDANNYAPVFEN-----------------------AP-YT 475
             A D G    S +  ++I++ D N+  P F                          P Y 
Sbjct: 1370 IAKDGGKIKMSSSVDIEIHVQDVNDNPPRFYGFQEMGRLPSNLVDVYRKDSKQVLVPIYY 1429

Query: 476  ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
            ASV E++ +GT V  + A DSD   N      +  +I +  V    Q F I+ + G +TT
Sbjct: 1430 ASVPENSQVGTIVTKIHANDSDFAGNGNGV--ILFDIPH--VRGQMQYFSIDNKEGLVTT 1485

Query: 536  NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN-----EPVFKQQLYTANI 590
               LD ET + + LT+ A D G PSL+ T  + + ++DV++       PVF+ + Y   +
Sbjct: 1486 VGNLDYETQNVHNLTIVASDLGSPSLTSTALLIVRILDVDEGPDEPKRPVFQHRYYEVEV 1545

Query: 591  MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650
             E++ V   +  +  +D +     R    LD  D  E  F +DP +G +    + DRE  
Sbjct: 1546 EENSPVPMRILDLNVSDNNKDEQIRYSIILDEGDGRE-HFSLDPKNGSLFLLTSPDREVR 1604

Query: 651  ATHDLKA----VAIDGGTPPQSSTVI-------------VHIKIEDINDSPPVFESDC-- 691
              ++LK     V    G P     V+             + +K++D+ND+ P F+++   
Sbjct: 1605 DRYELKVRVDKVKTSRGMPVMIYPVVGKRLNGLGPNEAKIILKVKDVNDNAPRFKTNGRP 1664

Query: 692  LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG--DDSNSFSLETRQGSDKA 746
            +   +  ++  G  + ++ A DPDEG N  V Y I GG   DS  F+++   G  +A
Sbjct: 1665 ILAVLPTSAYYGYNVIKVEAEDPDEGANGQVRYQILGGREQDSPKFAIDPVSGQVQA 1721



 Score =  120 bits (290), Expect = 4e-25
 Identities = 106/350 (30%), Positives = 168/350 (48%), Gaps = 50/350 (14%)

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN--------EAVAHHDQQFVINPQTG 531
            E+  IG  ++ + A D D G NA+ITY++ SEI          ++ +   + FV++ ++G
Sbjct: 1187 ENVTIGIPIIRLVARDPDDGKNAEITYNILSEIGGRTSFDSKTKSSSVVKRYFVMDSRSG 1246

Query: 532  AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
             I+    L  ET    +L + ARD G   L D   + +   DVND+ PVFKQ  Y  ++ 
Sbjct: 1247 EISVAGALPAET--DIVLEIAARDHG--GLMDNVTIRVHAFDVNDHAPVFKQSWYLFDVP 1302

Query: 592  EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG-SFVIDPASGVIRTNKALDRESV 650
            E       + +  ATDAD G N  I YEL P + +    F +    G       LDRE+ 
Sbjct: 1303 EGNFKRFEMGRFEATDADFGDNANITYELVPTNLDNSVKFEVSRYQGTFSLGGNLDRETR 1362

Query: 651  ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF---------ESDCLTFY------ 695
              ++ K +A DGG    SS+V + I ++D+ND+PP F          S+ +  Y      
Sbjct: 1363 DLYNFKVIAKDGGKIKMSSSVDIEIHVQDVNDNPPRFYGFQEMGRLPSNLVDVYRKDSKQ 1422

Query: 696  ---------ISENSPIGTTIGEIRAHDPD--EGPNAVVHYSIKG-GDDSNSFSLETRQGS 743
                     + ENS +GT + +I A+D D     N V+ + I         FS++ ++G 
Sbjct: 1423 VLVPIYYASVPENSQVGTIVTKIHANDSDFAGNGNGVILFDIPHVRGQMQYFSIDNKEG- 1481

Query: 744  DKAELVTMV-DLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVND 789
                LVT V +LDYE+ +  + L I A+   SP L +   + + + DV++
Sbjct: 1482 ----LVTTVGNLDYET-QNVHNLTIVASDLGSPSLTSTALLIVRILDVDE 1526



 Score =  119 bits (287), Expect = 1e-24
 Identities = 188/753 (24%), Positives = 311/753 (41%), Gaps = 95/753 (12%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVL-TLKATDQDIGKNAEVEYTIELVTADT 69
            I V D +D++P+F    YE  + E + +GT V+ T   + +D  +++   +T+    +D 
Sbjct: 1024 IIVDDEDDNAPIFSASAYEGRISENSQTGTEVIMTNHVSARDPDEDSSFMFTLRGEGSDL 1083

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ----ASP 125
               +             + + R +     L   A   ++K +  ++ +   D+     S 
Sbjct: 1084 FRIDRNTGRVFFIGNATELLDREEKPLYNLQIVAGERKKKSSNVSLTIHVDDENDNPPSF 1143

Query: 126  VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED---ISVTDNPVIA----KIKATD 178
            V   +     I V+  D  D  P  ++ T   + D     + V +N  I     ++ A D
Sbjct: 1144 VQMVILPDQGIRVSK-DKTDKDPAPTQLTSVTNSDYRSPLLYVPENVTIGIPIIRLVARD 1202

Query: 179  ADVGANSAIRYAI---IGGNTQMQ------------FSIDSLSGDVSLVKTLDYEQVRSY 223
             D G N+ I Y I   IGG T               F +DS SG++S+   L  E     
Sbjct: 1203 PDDGKNAEITYNILSEIGGRTSFDSKTKSSSVVKRYFVMDSRSGEISVAGALPAET--DI 1260

Query: 224  RLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYD 283
             L I A+D G     N T + ++  DVND+AP F  S +   V E     + + R +A D
Sbjct: 1261 VLEIAARDHGG-LMDNVT-IRVHAFDVNDHAPVFKQSWYLFDVPEGNFKRFEMGRFEATD 1318

Query: 284  ADEGVNAELTYTM--TDKD---------YTGNVDLPITIDPRSGWVYTSGQLDRE----- 327
            AD G NA +TY +  T+ D         Y G   L   +D  +  +Y    + ++     
Sbjct: 1319 ADFGDNANITYELVPTNLDNSVKFEVSRYQGTFSLGGNLDRETRDLYNFKVIAKDGGKIK 1378

Query: 328  TQAKYQLLVTATDGGD-PPR------SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380
              +   + +   D  D PPR                          +P  Y   + E+  
Sbjct: 1379 MSSSVDIEIHVQDVNDNPPRFYGFQEMGRLPSNLVDVYRKDSKQVLVPIYY-ASVPENSQ 1437

Query: 381  PGTPVVTLTATDADEDNRLHYEITGG--NTRGRFSITS-QNGRGLITVAQPLDFKQERRY 437
             GT V  + A D+D     +  I     + RG+    S  N  GL+T    LD++ +  +
Sbjct: 1438 VGTIVTKIHANDSDFAGNGNGVILFDIPHVRGQMQYFSIDNKEGLVTTVGNLDYETQNVH 1497

Query: 438  VLTVSATDSGGRS--DTAMVQINITDANN-----YAPVFENAPYTASVFEDAPIGTTVLV 490
             LT+ A+D G  S   TA++ + I D +        PVF++  Y   V E++P+   +L 
Sbjct: 1498 NLTIVASDLGSPSLTSTALLIVRILDVDEGPDEPKRPVFQHRYYEVEVEENSPVPMRILD 1557

Query: 491  VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550
            ++ +D++   + QI YS+   I +E      + F ++P+ G++      DRE    Y L 
Sbjct: 1558 LNVSDNNK--DEQIRYSI---ILDEGDGR--EHFSLDPKNGSLFLLTSPDREVRDRYELK 1610

Query: 551  VTA----RDGGVPSL-------------SDTTDVEISVVDVNDNEPVFKQ--QLYTANIM 591
            V         G+P +              +   + + V DVNDN P FK   +   A + 
Sbjct: 1611 VRVDKVKTSRGMPVMIYPVVGKRLNGLGPNEAKIILKVKDVNDNAPRFKTNGRPILAVLP 1670

Query: 592  EDALVGTSVSQVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGVIRT--NKALDRE 648
              A  G +V +V A D D G NG++ Y+ L  ++++   F IDP SG ++   N A D  
Sbjct: 1671 TSAYYGYNVIKVEAEDPDEGANGQVRYQILGGREQDSPKFAIDPVSGQVQAAGNFARDAG 1730

Query: 649  SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681
             V   D+KA    G    +SS   V + + D N
Sbjct: 1731 RVFGFDVKATDRAGAEDGRSSIANVFVYVLDDN 1763


>UniRef50_UPI0000E48BDB Cluster: PREDICTED: similar to FAT tumor
            suppressor homolog 4, partial; n=3; Strongylocentrotus
            purpuratus|Rep: PREDICTED: similar to FAT tumor
            suppressor homolog 4, partial - Strongylocentrotus
            purpuratus
          Length = 1282

 Score =  202 bits (492), Expect = 1e-49
 Identities = 214/810 (26%), Positives = 354/810 (43%), Gaps = 106/810 (13%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I+V D N+H+P F     E  + E   + ++V T++A D D+  +A +EY+I     +T 
Sbjct: 547  IDVTDVNEHAPTFAEGVVEVDIEEEVPTDSSVYTVQANDLDV--DAILEYSI----GETA 600

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREK-VARYTVLVKATDQASPVSDR 129
             P                 F ID ++G + T   LDR++    Y + V   D  +     
Sbjct: 601  GP-----------------FAIDSKTGEISTDGRLDRDEGTTAYNITVVVMDGTN----- 638

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
                  + + + D NDN P+F+  +  +SV E+   TD  ++  I+ATD D G N+ I Y
Sbjct: 639  -EDDCLVTITLTDINDNAPEFTGGSQALSVSEN--TTDTEMLQVIEATDIDEGVNAEIVY 695

Query: 190  AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             +   +  + FS+D+ +G +      DYE V+ Y LVI A D    + +  T   + I D
Sbjct: 696  VLESPDDGL-FSVDNETGMLYAHGPFDYEAVKEYTLVISASDSKFLTLTTVT---VTITD 751

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            VNDNAP F +      V E+V +   I  V A D D      + Y++       + D+P 
Sbjct: 752  VNDNAPVFISFCLNIEVLEDVGVDDVICTVGAVDDDGDGEDTVLYSLDPS----SGDVPF 807

Query: 310  TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
             ++  +G + T G LDRET+  Y + + A D G+PP S+  T              F   
Sbjct: 808  NVNQLTGEIKTDGTLDRETEDIYIITIIAEDSGEPPLSSNTTITVIVLDVNDNIPMFAKT 867

Query: 370  QYEVELAEDEPPGTPVVTLTATDADED----NRLHYEITGGNTRGRFSITSQNGRGLITV 425
               V L  D+    PV+       D+D    N    E TGG       +T Q+G   I  
Sbjct: 868  SITVRLQTDDLADPPVLLSRVKATDDDLAPWNITQCEKTGGED-SFVVLTGQDGSCEIYA 926

Query: 426  AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
             + L    +   V   +         +A V + +   +    V          FE+    
Sbjct: 927  YEELPLSTDPYSVSFYAFNPDNRDRPSANVTLTVDIRDTVCDV---------TFENEADD 977

Query: 486  TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
              +++ S  +++V +   +T +++S  +++ +            TG +    ++    M 
Sbjct: 978  DVIVLKSELETNVPV---VTLNVTSNCNSDDI------------TGEVFPTDIV----ME 1018

Query: 546  G-YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604
            G Y+L V A +   P +S+TT+V I V   N   P F++  YT +I ED++  T V  +G
Sbjct: 1019 GKYILLVRAYNQSDPEVSETTEVTIVVTGEN-TAPAFEEPFYTVDITEDSM--TMVIDLG 1075

Query: 605  --ATDADVG--LNGRIHY----ELDPKDREEGSFVIDPASGVIRTNKA-LDRESVATHDL 655
               TD D     NG + +    E D        F +  +SG++ T +A L+     T  +
Sbjct: 1076 PEVTDVDTPSFANGELSFSKVSETDGSGSSTDYFEVS-SSGIVTTTQANLNLIKSGTFQV 1134

Query: 656  KAVAIDGGTPPQSST--VIVHIKIEDIND---SPPVFESDCL-TFYISENSPIGTTIGEI 709
              + IDG   P S+T  VI+++ I+D ++   SPP+   DC  T  I E +     I  +
Sbjct: 1135 DVMVIDGAIEPLSNTTVVIINVDIDDQSNPVVSPPMITKDCPDTVEIEEETASPVDICRV 1194

Query: 710  RAHDPDEGPNAVVHYSIKGGDDS-NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768
                   G +A     + G + +   F++ T  G    E+ T   +DYE+  + Y L++ 
Sbjct: 1195 ------SGSSAYDDEVVFGLESALEYFNIGTVSG----EITTTKKIDYETDERSYTLLVY 1244

Query: 769  A--ASPPLWNDVRVEILVTDVNDNAPVMKD 796
            A   +  L N     ++VTD+NDNAPV  +
Sbjct: 1245 AEGTTSKLRNYTSFTVIVTDINDNAPVFSE 1274



 Score =  194 bits (472), Expect = 4e-47
 Identities = 150/488 (30%), Positives = 232/488 (47%), Gaps = 35/488 (7%)

Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI---R 188
           S   + V ++ D    P F++ +Y  +V E+    +   I +++A ++D+ +   +   +
Sbjct: 434 SVTNVTVRLMPDG-LAPNFTQSSYLGNVSEN--APEGTDIIQVEAINSDMTSEGIVYLLQ 490

Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDG-GSPSRSNTTQLLIN 246
            A  GG     FS+D+ SGDVS+V+  LD E+V+ Y L++ A D  G+  R + T ++I+
Sbjct: 491 MASDGGEDV--FSVDAESGDVSVVEDGLDAEKVKQYTLIVEAVDERGTYYRYSITSVIID 548

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
           + DVN++AP F   + +  + E VP   S+  VQA D D  V+A L Y++      G   
Sbjct: 549 VTDVNEHAPTFAEGVVEVDIEEEVPTDSSVYTVQANDLD--VDAILEYSI------GETA 600

Query: 307 LPITIDPRSGWVYTSGQLDR-ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
            P  ID ++G + T G+LDR E    Y + V   DG +                      
Sbjct: 601 GPFAIDSKTGEISTDGRLDRDEGTTAYNITVVVMDGTNED---DCLVTITLTDINDNAPE 657

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQNGRGLIT 424
           F  G   + ++E+      +  + ATD DE  N     +      G FS+   N  G++ 
Sbjct: 658 FTGGSQALSVSENTTDTEMLQVIEATDIDEGVNAEIVYVLESPDDGLFSV--DNETGMLY 715

Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
              P D++  + Y L +SA+DS   + T  V + ITD N+ APVF +      V ED  +
Sbjct: 716 AHGPFDYEAVKEYTLVISASDSKFLTLTT-VTVTITDVNDNAPVFISFCLNIEVLEDVGV 774

Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
              +  V A D D      + YSL            D  F +N  TG I T+  LDRET 
Sbjct: 775 DDVICTVGAVDDDGDGEDTVLYSLDPSSG-------DVPFNVNQLTGEIKTDGTLDRETE 827

Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV--SQ 602
             Y++T+ A D G P LS  T + + V+DVNDN P+F +   T  +  D L    V  S+
Sbjct: 828 DIYIITIIAEDSGEPPLSSNTTITVIVLDVNDNIPMFAKTSITVRLQTDDLADPPVLLSR 887

Query: 603 VGATDADV 610
           V ATD D+
Sbjct: 888 VKATDDDL 895



 Score =  193 bits (470), Expect = 7e-47
 Identities = 149/494 (30%), Positives = 228/494 (46%), Gaps = 26/494 (5%)

Query: 245 INIRDVNDN-APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303
           + +R + D  AP F  S +  +VSEN P G  I++V+A ++D  + +E    +      G
Sbjct: 438 VTVRLMPDGLAPNFTQSSYLGNVSENAPEGTDIIQVEAINSD--MTSEGIVYLLQMASDG 495

Query: 304 NVDLPITIDPRSGWV-YTSGQLDRETQAKYQLLVTATDG-GDPPRSATATXXXXXXXXXX 361
             D+  ++D  SG V      LD E   +Y L+V A D  G   R +  +          
Sbjct: 496 GEDV-FSVDAESGDVSVVEDGLDAEKVKQYTLIVEAVDERGTYYRYSITSVIIDVTDVNE 554

Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421
               F  G  EV++ E+ P  + V T+ A D D D  L Y I  G T G F+I S+ G  
Sbjct: 555 HAPTFAEGVVEVDIEEEVPTDSSVYTVQANDLDVDAILEYSI--GETAGPFAIDSKTGE- 611

Query: 422 LITVAQPLDFKQ-ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
            I+    LD  +    Y +TV   D G   D  +V I +TD N+ AP F       SV E
Sbjct: 612 -ISTDGRLDRDEGTTAYNITVVVMD-GTNEDDCLVTITLTDINDNAPEFTGGSQALSVSE 669

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           +      + V+ ATD D G+NA+I Y L S          D  F ++ +TG +  +   D
Sbjct: 670 NTTDTEMLQVIEATDIDEGVNAEIVYVLESP--------DDGLFSVDNETGMLYAHGPFD 721

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
            E +  Y L ++A D    +L   T V +++ DVNDN PVF        ++ED  V   +
Sbjct: 722 YEAVKEYTLVISASDSKFLTL---TTVTVTITDVNDNAPVFISFCLNIEVLEDVGVDDVI 778

Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
             VGA D D      + Y LDP   +   F ++  +G I+T+  LDRE+   + +  +A 
Sbjct: 779 CTVGAVDDDGDGEDTVLYSLDPSSGDV-PFNVNQLTGEIKTDGTLDRETEDIYIITIIAE 837

Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN--SPIGTTIGEIRAHDPDEGP 718
           D G PP SS   + + + D+ND+ P+F    +T  +  +  +     +  ++A D D  P
Sbjct: 838 DSGEPPLSSNTTITVIVLDVNDNIPMFAKTSITVRLQTDDLADPPVLLSRVKATDDDLAP 897

Query: 719 NAVVHYSIKGGDDS 732
             +      GG+DS
Sbjct: 898 WNITQCEKTGGEDS 911



 Score =  182 bits (443), Expect = 1e-43
 Identities = 188/746 (25%), Positives = 313/746 (41%), Gaps = 52/746 (6%)

Query: 99  LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158
           L    ++D E    Y   + A D      +      T+ V +ID +D  P FS+  Y V+
Sbjct: 181 LRLNGTVDFEDQEFYNFTLIAEDGCKSGFNSREGYVTVIVQVIDTDDEPPAFSQDNYDVT 240

Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ----FSIDSLSGDVSLVKT 214
           + E  S     V   + A++ D   N+ +RY+ I    +        ID L+ DV++   
Sbjct: 241 IPERNSTF---VYTGLSASNGD-SFNTPLRYSFIEQRGEWSCLYYLKIDPLTADVTIRNE 296

Query: 215 LDYEQVRSYRLV-IRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI- 272
           LD+E      ++ ++A      +   TT L + + +V +  P F    +   ++E+ P  
Sbjct: 297 LDFETSPGTCIITVQAVQENDFNMVGTTNLTVTVMNVEE-CPSFILQSYSGQLTEDDPFV 355

Query: 273 ---GYSIVRVQAYDADEGVNAELTYTM-TDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328
              G S   +     ++GV    +Y    D      +++P     R   +        E+
Sbjct: 356 ITDGGSERLIMGMTDEDGVFGGPSYIEPNDTIELVEMNMPEGTMTRFFLIKFLDPASIES 415

Query: 329 QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388
             K Q+ ++  D  D     + T              F    Y   ++E+ P GT ++ +
Sbjct: 416 DTKIQIFLS-NDTADM-ECDSVTNVTVRLMPDGLAPNFTQSSYLGNVSENAPEGTDIIQV 473

Query: 389 TATDADEDNR-LHYEITGGNTRGR--FSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445
            A ++D  +  + Y +   +  G   FS+ +++G  +  V   LD ++ ++Y L V A D
Sbjct: 474 EAINSDMTSEGIVYLLQMASDGGEDVFSVDAESG-DVSVVEDGLDAEKVKQYTLIVEAVD 532

Query: 446 SGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502
             G   R     V I++TD N +AP F        + E+ P  ++V  V A D DV  +A
Sbjct: 533 ERGTYYRYSITSVIIDVTDVNEHAPTFAEGVVEVDIEEEVPTDSSVYTVQANDLDV--DA 590

Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR-ETMSGYLLTVTARDGGVPSL 561
            + YS+               F I+ +TG I+T+  LDR E  + Y +TV   DG   + 
Sbjct: 591 ILEYSIGETAG---------PFAIDSKTGEISTDGRLDRDEGTTAYNITVVVMDG---TN 638

Query: 562 SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621
            D   V I++ D+NDN P F       ++ E+      +  + ATD D G+N  I Y L+
Sbjct: 639 EDDCLVTITLTDINDNAPEFTGGSQALSVSENTTDTEMLQVIEATDIDEGVNAEIVYVLE 698

Query: 622 PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681
             D  +G F +D  +G++  +   D E+V  + L   A D       +   V + I D+N
Sbjct: 699 SPD--DGLFSVDNETGMLYAHGPFDYEAVKEYTLVISASDSKF---LTLTTVTVTITDVN 753

Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741
           D+ PVF S CL   + E+  +   I  + A D D      V YS+        F++    
Sbjct: 754 DNAPVFISFCLNIEVLEDVGVDDVICTVGAVDDDGDGEDTVLYSLDPSSGDVPFNVNQLT 813

Query: 742 GSDKAELVTMVDLDYESPRKKYELVIR--AASPPLWNDVRVEILVTDVNDNAPVMKDFQI 799
           G    E+ T   LD E+       +I   +  PPL ++  + ++V DVNDN P+     I
Sbjct: 814 G----EIKTDGTLDRETEDIYIITIIAEDSGEPPLSSNTTITVIVLDVNDNIPMFAKTSI 869

Query: 800 IFNNYKDCFPVGP--FGRVPAYDADV 823
                 D     P    RV A D D+
Sbjct: 870 TVRLQTDDLADPPVLLSRVKATDDDL 895


>UniRef50_Q9P2E7 Cluster: Protocadherin-10 precursor; n=34;
           Euteleostomi|Rep: Protocadherin-10 precursor - Homo
           sapiens (Human)
          Length = 1040

 Score =  202 bits (492), Expect = 1e-49
 Identities = 182/625 (29%), Positives = 270/625 (43%), Gaps = 55/625 (8%)

Query: 96  SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155
           +G L     +DRE++ + +             +       + + ++D NDN P F E   
Sbjct: 70  TGVLYVNEKIDREQICKQSP--SCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEPDL 127

Query: 156 TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSID-SLSGD------ 208
           TV + E  S T         A D DVG NS   Y I   +    FS+D    GD      
Sbjct: 128 TVEISE--SATPGTRFPLESAFDPDVGTNSLRDYEITPNS---YFSLDVQTQGDGNRFAE 182

Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGS-------------------PSRSNTTQLLINIRD 249
           + L K LD EQ   +R V+ A DGG                      R+ T  L I + D
Sbjct: 183 LVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLD 242

Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            NDN P F   ++  S+ EN P G  ++++ A D DEG N E+ Y+ +        +L  
Sbjct: 243 SNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL-F 301

Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
            + PR+G +  SG+LD E    YQ+ V A D G     A                     
Sbjct: 302 GLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFS 361

Query: 370 QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
             +  ++E   PGT V   + TD D  E+ ++  E+  G+   R   + +N   ++T A 
Sbjct: 362 TVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELL-GDVPFRLKSSFKNYYTIVTEA- 419

Query: 428 PLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
           PLD +    Y LTV A D G    S +  +Q+ ++D N+ AP F    Y   V E+   G
Sbjct: 420 PLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPG 479

Query: 486 TTVLVVSATDSDVGINAQITYS-LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
             +  VSATD D G NAQ+ YS L  +I   +V  +     IN + G +   +  D E +
Sbjct: 480 AYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTY---VSINSENGYLYALRSFDYEQL 536

Query: 545 SGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTAN-------IMEDALV 596
             +   V ARD G P +L+    V I +VD NDN P     L   N       +   A  
Sbjct: 537 KDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEP 596

Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL--DRESVATHD 654
           G  +++V A DAD G N R+ Y +  +  E   F +D  +G +RT + +   R+    ++
Sbjct: 597 GYLLTRVAAVDADDGENARLTYSI-VRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYE 655

Query: 655 LKAVAIDGGTPPQSSTVIVHIKIED 679
           L     D G PP SST  + +++ D
Sbjct: 656 LVIEVRDHGQPPLSSTATLVVQLVD 680



 Score =  191 bits (465), Expect = 3e-46
 Identities = 167/587 (28%), Positives = 255/587 (43%), Gaps = 55/587 (9%)

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
           Q+ I + D+NDN P F        +SE+   G       A+D D G N+   Y +T   Y
Sbjct: 107 QVEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSY 166

Query: 302 TGNVDLPITIDP-RSGWVYTSGQLDRETQAKYQLLVTATDGGD----------------P 344
             ++D+    D  R   +     LDRE QA ++ ++TA DGG                 P
Sbjct: 167 F-SLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLP 225

Query: 345 P---RSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRL 399
           P   R+ TA               F    Y V L E+ PPGT V+ L ATD DE  +  +
Sbjct: 226 PQQQRTGTALLTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEV 285

Query: 400 HYEITGG---NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA--M 454
            Y  +       R  F ++ + GR  + V+  LD+++   Y + V A D G  +  A   
Sbjct: 286 VYSFSSHISPRARELFGLSPRTGR--LEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCK 343

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           V + + DAN+ AP    +    +V E A  GT V + S TD D   N Q+   L  ++  
Sbjct: 344 VLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPF 403

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
              +     + I        T   LDRE    Y LTV ARD G P+LS +  +++ V DV
Sbjct: 404 RLKSSFKNYYTI-------VTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDV 456

Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY---ELDPKDREEGSFV 631
           NDN P F Q +Y   + E+ + G  +  V ATD D G N ++ Y   E   +     ++V
Sbjct: 457 NDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYV 516

Query: 632 -IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPVFES 689
            I+  +G +   ++ D E +     +  A D G+P   +    V+I I D ND+ P   +
Sbjct: 517 SINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVA 576

Query: 690 DC-------LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
                        +  ++  G  +  + A D D+G NA + YSI  G++ N F ++ R G
Sbjct: 577 PLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTG 636

Query: 743 SDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTD 786
             +         D   P++ YELVI       PPL +   + + + D
Sbjct: 637 ELRTARRVPAKRD---PQRPYELVIEVRDHGQPPLSSTATLVVQLVD 680



 Score =  181 bits (440), Expect = 3e-43
 Identities = 162/518 (31%), Positives = 236/518 (45%), Gaps = 49/518 (9%)

Query: 373 VELAEDEPPGTPVVTLTATDADED-NRLH-YEITGGNTRGRFSITSQNGRGL--ITVAQP 428
           VE++E   PGT     +A D D   N L  YEIT  +       T  +G     + + +P
Sbjct: 129 VEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVLEKP 188

Query: 429 LDFKQE--RRYVLTVSATDSGG-------------------RSDTAMVQINITDANNYAP 467
           LD +Q+   RYVLT      GG                   R+ TA++ I + D+N+  P
Sbjct: 189 LDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVP 248

Query: 468 VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527
            F+   YT S+ E++P GT V+ ++ATD D G N ++ YS SS IS  A     + F ++
Sbjct: 249 AFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRA----RELFGLS 304

Query: 528 PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT 587
           P+TG +  +  LD E    Y + V A+D G  ++     V + V+D NDN P        
Sbjct: 305 PRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVK 364

Query: 588 ANIMEDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKAL 645
             + E A  GT V+    TD D   NG++  EL  D   R + SF        I T   L
Sbjct: 365 EAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSF---KNYYTIVTEAPL 421

Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
           DRE+  ++ L  VA D G P  S++  + +++ D+ND+ P F       Y++EN+  G  
Sbjct: 422 DREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAY 481

Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGD-DSNSFSLETRQGSDKAELVTMVDLDYESPRK-KY 763
           I  + A D DEG NA + YSI        S        S+   L  +   DYE  +   +
Sbjct: 482 IYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSF 541

Query: 764 ELVIRAASPP--LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP--------F 813
           ++  R A  P  L  +  V IL+ D NDNAP +    +   N      V P         
Sbjct: 542 QVEARDAGSPQALAGNATVNILIVDQNDNAPAIV-APLPGRNGTPAREVLPRSAEPGYLL 600

Query: 814 GRVPAYDADVTD--KLQYRILSGNNANLILLNETTGSM 849
            RV A DAD  +  +L Y I+ GN  NL  ++  TG +
Sbjct: 601 TRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGEL 638



 Score =  167 bits (406), Expect = 4e-39
 Identities = 158/602 (26%), Positives = 257/602 (42%), Gaps = 68/602 (11%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +I VLD ND+ P F        + E A+ GT      A D D+G N+  +Y I   +  +
Sbjct: 109 EIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFS 168

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQAS---- 124
           L+ +                   DG R   L+    LDRE+ A +  ++ A D       
Sbjct: 169 LDVQTQG----------------DGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGV 212

Query: 125 ------------PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIA 172
                       P   + + TA + + ++D NDN P F +  YTVS+ E  +     ++ 
Sbjct: 213 GEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVYTVSLPE--NSPPGTLVI 270

Query: 173 KIKATDADVGANSAIRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA 229
           ++ ATD D G N  + Y+    I    +  F +   +G + +   LDYE+   Y++ ++A
Sbjct: 271 QLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQA 330

Query: 230 QDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN 289
           +D G  +     ++L+ + D NDNAP    S  +E+VSE    G  +      D D   N
Sbjct: 331 KDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEEN 390

Query: 290 AELTYTMTDKDYTGNVDLPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348
            ++       +  G+V   +    ++ + + T   LDRE    Y L V A D G+P  S 
Sbjct: 391 GQV-----QCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALST 445

Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGG 406
           + +              F    Y+V + E+  PG  +  ++ATD DE  + +L Y I   
Sbjct: 446 SKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILEC 505

Query: 407 NTRGR--FSITSQNG-RGLITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINIT 460
             +G   F+  S N   G +   +  D++Q + +   V A D+G     +  A V I I 
Sbjct: 506 QIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIV 565

Query: 461 DANNYAPVF-------ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513
           D N+ AP            P    +   A  G  +  V+A D+D G NA++TYS+     
Sbjct: 566 DQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVR--G 623

Query: 514 NEAVAHHDQQFVINPQTGAITTNKLL--DRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571
           NE        F ++ +TG + T + +   R+    Y L +  RD G P LS T  + + +
Sbjct: 624 NEM-----NLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQL 678

Query: 572 VD 573
           VD
Sbjct: 679 VD 680



 Score =  148 bits (358), Expect = 3e-33
 Identities = 116/365 (31%), Positives = 180/365 (49%), Gaps = 43/365 (11%)

Query: 2   SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
           +VP      + VLD ND++P       + +V EGA+ GT V     TD+D  +N +V+  
Sbjct: 337 AVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQ-- 394

Query: 62  IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121
            EL+                    ++  F+       ++T A LDRE    YT+ V A D
Sbjct: 395 CELL--------------GDVPFRLKSSFK---NYYTIVTEAPLDREAGDSYTLTVVARD 437

Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181
           +  P    LS++ +I V + D NDN P+FS+  Y V V E  +      I  + ATD D 
Sbjct: 438 RGEPA---LSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTE--NNVPGAYIYAVSATDRDE 492

Query: 182 GANSAIRYAII-----GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP- 235
           GAN+ + Y+I+     G +     SI+S +G +  +++ DYEQ++ +   + A+D GSP 
Sbjct: 493 GANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQ 552

Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSL-------FQESVSENVPIGYSIVRVQAYDADEGV 288
           + +    + I I D NDNAP     L        +E +  +   GY + RV A DAD+G 
Sbjct: 553 ALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGE 612

Query: 289 NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL--DRETQAKYQLLVTATDGGDPPR 346
           NA LTY++      GN      +D R+G + T+ ++   R+ Q  Y+L++   D G PP 
Sbjct: 613 NARLTYSIV----RGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPL 668

Query: 347 SATAT 351
           S+TAT
Sbjct: 669 SSTAT 673



 Score =  103 bits (247), Expect = 7e-20
 Identities = 93/299 (31%), Positives = 131/299 (43%), Gaps = 40/299 (13%)

Query: 526 INPQTGAITTNKLLDRETMSGYLLT-VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584
           +N +TG +  N+ +DRE +     + V   +  + +  +   VEI V+D+NDN P F + 
Sbjct: 66  LNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEP 125

Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS-------G 637
             T  I E A  GT      A D DVG N    YE+ P       F +D  +        
Sbjct: 126 DLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITP----NSYFSLDVQTQGDGNRFA 181

Query: 638 VIRTNKALDRESVATHDLKAVAIDG----------------GTPPQ---SSTVIVHIKIE 678
            +   K LDRE  A H     A+DG                G PPQ   + T ++ I++ 
Sbjct: 182 ELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVL 241

Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS---F 735
           D ND+ P F+    T  + ENSP GT + ++ A DPDEG N  V YS        +   F
Sbjct: 242 DSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELF 301

Query: 736 SLETRQGSDKAELVTMVDLDY-ESPRKKYELVIRAASP-PLWNDVRVEILVTDVNDNAP 792
            L  R G     L    +LDY ESP  +  +  +   P  +    +V + V D NDNAP
Sbjct: 302 GLSPRTG----RLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAP 356



 Score = 57.2 bits (132), Expect = 6e-06
 Identities = 55/185 (29%), Positives = 82/185 (44%), Gaps = 11/185 (5%)

Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGAT-DADVGLNGRIHYELDPKDREEGSFVIDPAS 636
           E VF Q  YT  + E+   GT V  +      D+       ++  P  R      ++  +
Sbjct: 14  EGVFSQLHYT--VQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTP-YLDLNLET 70

Query: 637 GVIRTNKALDRESVATHDLKAVA-IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695
           GV+  N+ +DRE +       V  ++           V I++ DIND+PP F    LT  
Sbjct: 71  GVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEPDLTVE 130

Query: 696 ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR---QGSDKAELVTMV 752
           ISE++  GT      A DPD G N++  Y I     ++ FSL+ +    G+  AELV   
Sbjct: 131 ISESATPGTRFPLESAFDPDVGTNSLRDYEI---TPNSYFSLDVQTQGDGNRFAELVLEK 187

Query: 753 DLDYE 757
            LD E
Sbjct: 188 PLDRE 192


>UniRef50_Q9HBT6 Cluster: Cadherin-20 precursor; n=261;
           Euteleostomi|Rep: Cadherin-20 precursor - Homo sapiens
           (Human)
          Length = 801

 Score =  201 bits (490), Expect = 3e-49
 Identities = 164/549 (29%), Positives = 263/549 (47%), Gaps = 46/549 (8%)

Query: 161 EDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV 220
           E+ + TD   + K+ + D D G  S I+Y + G    + F+ID  +GD+  ++ LD E+ 
Sbjct: 70  EEYTGTDPLYVGKLHS-DMDRGDGS-IKYILSGEGAGIVFTIDDTTGDIHAIQRLDREER 127

Query: 221 RSYRLVIRAQD--GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR 278
             Y L  +A D   G P     ++ +I I+D+NDN P+F    +  +V E  P+G S+++
Sbjct: 128 AQYTLRAQALDRRTGRPMEPE-SEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQ 186

Query: 279 VQAYDADE---GVNAELTYT-MTDKDYTGNVDLPITIDPRSGWVYTS-GQLDRETQAKYQ 333
           V A DAD+   G +A + Y+ +  + Y        ++D ++G + T+   +DRE +  Y+
Sbjct: 187 VTATDADDPTYGNSARVVYSILQGQPY-------FSVDSKTGVIRTALMNMDREAKEYYE 239

Query: 334 LLVTATD-GGD-PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTAT 391
           +++ A D GG     + T T              F    Y++ + E  P  + V  + A 
Sbjct: 240 VIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAK 299

Query: 392 DADE--DNRLHYEITGGNTRGRFSI-TSQNGR-GLITVAQPLDFKQERRYVLTVSATDS- 446
           D DE  +  + Y I  G+    F I T  N + G+ITV +PL F+ ++ Y L V   +  
Sbjct: 300 DLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPH 359

Query: 447 --------GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498
                   G   DT  V I++ D +   PVFE   Y   V ED  IGTT+ ++SA D DV
Sbjct: 360 LEMRFLNLGPFQDTTTVHISVEDVDE-PPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDV 418

Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558
             N  I YS+      +  +   + F ++  TGA+ T + LDRE  S + +TV A +   
Sbjct: 419 -TNNSIRYSI------DRSSDPGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNN 471

Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR-IH 617
           PS   +  V I V+DVNDN P F  + Y A + E+A  G  +  V A D D   NG+  +
Sbjct: 472 PSQVGSVPVTIKVLDVNDNAPEF-PRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFY 530

Query: 618 YELDPKDREEGSFVI----DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673
           Y L P+     +F I    D  + ++       ++  +   L  +  D G P  SST  +
Sbjct: 531 YSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTL 590

Query: 674 HIKIEDIND 682
            I++   +D
Sbjct: 591 TIQVCSCDD 599



 Score =  188 bits (457), Expect = 3e-45
 Identities = 152/506 (30%), Positives = 226/506 (44%), Gaps = 30/506 (5%)

Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSATATXXXXXXXXXXXXXXFMP 368
           TID  +G ++   +LDRE +A+Y L   A D     P    +               F+ 
Sbjct: 108 TIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLD 167

Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDN-----RLHYEITGGNTRGRFSITSQNGRGLI 423
           G Y   + E  P GT V+ +TATDAD+       R+ Y I  G     FS+ S+ G  + 
Sbjct: 168 GPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQPY--FSVDSKTGV-IR 224

Query: 424 TVAQPLDFKQERRYVLTVSATDSGGR----SDTAMVQINITDANNYAPVFENAPYTASVF 479
           T    +D + +  Y + + A D GG+    + T  V I ++D N+  P F    Y  SV 
Sbjct: 225 TALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVL 284

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           E API +TV  V A D D GINA++ Y++   +  +     D     N Q G IT  K L
Sbjct: 285 ESAPISSTVGRVFAKDLDEGINAEMKYTI---VDGDGADAFDISTDPNFQVGIITVKKPL 341

Query: 540 DRETMSGYLLTVTARDG-------GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592
             E+   Y L V   +         +    DTT V ISV DV D  PVF+   Y   + E
Sbjct: 342 SFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDV-DEPPVFEPGFYFVEVPE 400

Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652
           D  +GT++  + A D DV  N  I Y +D        F +D  +G + T + LDRE  + 
Sbjct: 401 DVAIGTTIQIISAKDPDV-TNNSIRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSW 459

Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
           H++  +A++   P Q  +V V IK+ D+ND+ P F      F + EN+  G  I  + A 
Sbjct: 460 HNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAF-VCENAKAGQLIQTVSAV 518

Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK-AELVTMVDLDYESPRKKYELVIRAA- 770
           D D+  N    Y     + +N+ +   R   D  A ++T      +  +  + L I  A 
Sbjct: 519 DQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIAD 578

Query: 771 --SPPLWNDVRVEILVTDVNDNAPVM 794
              P L +   + I V   +D+  VM
Sbjct: 579 SGQPVLSSTGTLTIQVCSCDDDGHVM 604



 Score =  184 bits (449), Expect = 2e-44
 Identities = 159/507 (31%), Positives = 237/507 (46%), Gaps = 30/507 (5%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           VF ID  +G +     LDRE+ A+YT+  +A D+ +     +   +   + I D NDN P
Sbjct: 106 VFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRT--GRPMEPESEFIIKIQDINDNEP 163

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDAD---VGANSAIRYAIIGGNTQMQFSIDSL 205
           +F +  Y  +V E +S     VI ++ ATDAD    G ++ + Y+I+ G  Q  FS+DS 
Sbjct: 164 KFLDGPYVATVPE-MSPVGTSVI-QVTATDADDPTYGNSARVVYSILQG--QPYFSVDSK 219

Query: 206 SGDV-SLVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQLLINIRDVNDNAPRFYTSLF 262
           +G + + +  +D E    Y ++I+A+D G      + TT + I + DVNDN PRF    +
Sbjct: 220 TGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHY 279

Query: 263 QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322
           Q SV E+ PI  ++ RV A D DEG+NAE+ YT+ D D     D+    + + G +    
Sbjct: 280 QMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKK 339

Query: 323 QLDRETQAKYQLLVTATDGGDPPRSAT------ATXXXXXXXXXXXXXXFMPGQYEVELA 376
            L  E++  Y L V   +     R          T              F PG Y VE+ 
Sbjct: 340 PLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVP 399

Query: 377 EDEPPGTPVVTLTATDAD-EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435
           ED   GT +  ++A D D  +N + Y I   +  GRF         L+T A+PLD ++  
Sbjct: 400 EDVAIGTTIQIISAKDPDVTNNSIRYSIDRSSDPGRFFYVDITTGALMT-ARPLDREEFS 458

Query: 436 RYVLTVSATDSGGRSD--TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
            + +TV A +    S   +  V I + D N+ AP F    Y A V E+A  G  +  VSA
Sbjct: 459 WHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRF-YEAFVCENAKAGQLIQTVSA 517

Query: 494 TDSDVGINAQ-ITYSLSSEISNEA-VAHHDQQFVINPQTGAITTNKL-LDRETMSGYLLT 550
            D D   N Q   YSL+ E +N       D Q      T  I T +    ++  S + L 
Sbjct: 518 VDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQ----DNTARILTRRSGFRQQEQSVFHLP 573

Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDN 577
           +   D G P LS T  + I V   +D+
Sbjct: 574 ILIADSGQPVLSSTGTLTIQVCSCDDD 600



 Score =  164 bits (399), Expect = 3e-38
 Identities = 142/434 (32%), Positives = 207/434 (47%), Gaps = 40/434 (9%)

Query: 391 TDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG-G 448
           +D D  D  + Y ++G      F+I    G   I   Q LD ++  +Y L   A D   G
Sbjct: 85  SDMDRGDGSIKYILSGEGAGIVFTIDDTTGD--IHAIQRLDREERAQYTLRAQALDRRTG 142

Query: 449 R--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506
           R     +   I I D N+  P F + PY A+V E +P+GT+V+ V+ATD+D       TY
Sbjct: 143 RPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDAD-----DPTY 197

Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAITTNKL-LDRETMSGYLLTVTARD--GGVPSLSD 563
             S+ +   ++      F ++ +TG I T  + +DRE    Y + + A+D  G +  L+ 
Sbjct: 198 GNSARVVY-SILQGQPYFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAG 256

Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK 623
           TT V I++ DVNDN P F Q+ Y  +++E A + ++V +V A D D G+N  + Y +   
Sbjct: 257 TTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDG 316

Query: 624 DREEGSFV-IDP--ASGVIRTNKALDRESVATHDLKAVAIDGGTP----------PQSST 670
           D  +   +  DP    G+I   K L  ES  ++ LK   ++G  P          P   T
Sbjct: 317 DGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLK---VEGANPHLEMRFLNLGPFQDT 373

Query: 671 VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-KGG 729
             VHI +ED+ D PPVFE       + E+  IGTTI  I A DPD   N++  YSI +  
Sbjct: 374 TTVHISVEDV-DEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNSI-RYSIDRSS 431

Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYE--SPRKKYELVIRAASPPLWNDVRVEILVTDV 787
           D    F ++   G+    L+T   LD E  S      L +   +P     V V I V DV
Sbjct: 432 DPGRFFYVDITTGA----LMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDV 487

Query: 788 NDNAPVMKDFQIIF 801
           NDNAP    F   F
Sbjct: 488 NDNAPEFPRFYEAF 501



 Score =  133 bits (321), Expect = 8e-29
 Identities = 123/391 (31%), Positives = 183/391 (46%), Gaps = 35/391 (8%)

Query: 485 GTTVLVVSATDSDVGI-NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
           GT  L V    SD+   +  I Y LS E +          F I+  TG I   + LDRE 
Sbjct: 74  GTDPLYVGKLHSDMDRGDGSIKYILSGEGAGIV-------FTIDDTTGDIHAIQRLDREE 126

Query: 544 MSGYLLTVTARDG--GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
            + Y L   A D   G P +   ++  I + D+NDNEP F    Y A + E + VGTSV 
Sbjct: 127 RAQYTLRAQALDRRTGRP-MEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVI 185

Query: 602 QVGATDAD---VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA-LDRESVATHD--L 655
           QV ATDAD    G + R+ Y +    + +  F +D  +GVIRT    +DRE+   ++  +
Sbjct: 186 QVTATDADDPTYGNSARVVYSIL---QGQPYFSVDSKTGVIRTALMNMDREAKEYYEVII 242

Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
           +A  + G     + T  V+I + D+ND+PP F        + E++PI +T+G + A D D
Sbjct: 243 QAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLD 302

Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP--- 772
           EG NA + Y+I  GD +++F + T        +     L +ES +K Y L +  A+P   
Sbjct: 303 EGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFES-KKSYTLKVEGANPHLE 361

Query: 773 -------PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVT- 824
                  P  +   V I V DV D  PV +         +D         + A D DVT 
Sbjct: 362 MRFLNLGPFQDTTTVHISVEDV-DEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTN 420

Query: 825 DKLQYRI-LSGNNANLILLNETTGS-MTLSP 853
           + ++Y I  S +      ++ TTG+ MT  P
Sbjct: 421 NSIRYSIDRSSDPGRFFYVDITTGALMTARP 451



 Score =  120 bits (290), Expect = 4e-25
 Identities = 122/486 (25%), Positives = 209/486 (43%), Gaps = 53/486 (10%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVTA 67
           I + D ND+ P F    Y A+V E +  GT+V+ + ATD D    G +A V Y+I     
Sbjct: 153 IKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSI----- 207

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR-ASLDREKVARYTVLVKATDQASPV 126
                              Q  F +D ++G + T   ++DRE    Y V+++A D    +
Sbjct: 208 ----------------LQGQPYFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQL 251

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
              L+ T T+++ + D NDN P+F +K Y +SV E   ++    + ++ A D D G N+ 
Sbjct: 252 GG-LAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISS--TVGRVFAKDLDEGINAE 308

Query: 187 IRYAIIGGNTQMQFSIDS----LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR----- 237
           ++Y I+ G+    F I +      G +++ K L +E  +SY L +   +     R     
Sbjct: 309 MKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLG 368

Query: 238 --SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295
              +TT + I++ DV D  P F    +   V E+V IG +I  + A D D   N  + Y+
Sbjct: 369 PFQDTTTVHISVEDV-DEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDV-TNNSIRYS 426

Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355
           +      G       +D  +G + T+  LDRE  + + + V A +  +P +  +      
Sbjct: 427 IDRSSDPGRF---FYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIK 483

Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEIT---GGNTRGR 411
                     F P  YE  + E+   G  + T++A D D+  N  H+  +          
Sbjct: 484 VLDVNDNAPEF-PRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPN 542

Query: 412 FSITSQNGRGLITVAQPLDFKQERRYV--LTVSATDSGG--RSDTAMVQINITDANNYAP 467
           F+I          + +   F+Q+ + V  L +   DSG    S T  + I +   ++   
Sbjct: 543 FTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGH 602

Query: 468 VFENAP 473
           V   +P
Sbjct: 603 VMSCSP 608



 Score = 46.0 bits (104), Expect = 0.015
 Identities = 47/164 (28%), Positives = 75/164 (45%), Gaps = 23/164 (14%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I VLD ND++P F  + YEA V E A +G  + T+ A DQD  +N +  Y        +L
Sbjct: 482 IKVLDVNDNAPEFP-RFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYY-------SL 533

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            PE A            +  RI      L  R+   +++ + + + +   D   PV   L
Sbjct: 534 APEAANNPNFTIRDNQDNTARI------LTRRSGFRQQEQSVFHLPILIADSGQPV---L 584

Query: 131 SSTATIHVNI--IDDNDNYPQFSEKTYTVSVDEDISVTDNPVIA 172
           SST T+ + +   DD+ +    S + Y + V    S++  P+IA
Sbjct: 585 SSTGTLTIQVCSCDDDGHVMSCSPEAYMLPV----SLSRGPLIA 624


>UniRef50_Q6R0I8 Cluster: Cadherin-related neuronal receptor 3;
           n=23; Gallus gallus|Rep: Cadherin-related neuronal
           receptor 3 - Gallus gallus (Chicken)
          Length = 1000

 Score =  200 bits (487), Expect = 6e-49
 Identities = 143/445 (32%), Positives = 216/445 (48%), Gaps = 23/445 (5%)

Query: 368 PGQYE-VELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGR-FSITSQNGRGLI 423
           P  Y+ + +AE   PG+      A+DAD   + +L Y ++              N + L 
Sbjct: 132 PAAYKNISIAESSLPGSRFPLEGASDADIGSNAQLSYSLSPSEHFALDVKSPDDNLKSLF 191

Query: 424 TV-AQPLDFKQERRYVLTVSATDSGGRSDTAMVQ--INITDANNYAPVFENAPYTASVFE 480
            V   PLD +    + L ++A+D G  + T  VQ  I++ DAN+ AP F  + Y   + E
Sbjct: 192 LVLTHPLDRESLSEHRLVLTASDGGRPALTGTVQLVISVLDANDNAPQFNQSVYKVQLPE 251

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           DA  GT V  V+ATD DVG N + +YS+ S +     A     F I+P+TG I     LD
Sbjct: 252 DAAEGTLVARVAATDPDVGFNQEFSYSIVSSVP----ASQSDAFSIDPRTGEIRLTGPLD 307

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
            E +  + L + ARD G P LS    V + V+DVNDN P       +  + EDA +GT V
Sbjct: 308 FEDVHQHELQIEARDKGTPPLSGHCSVILEVLDVNDNAPEVWVTSLSVPVPEDAALGTVV 367

Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
           + +  +D D G NGR+   + P     G       S  +   +ALDRE V+ ++++  A 
Sbjct: 368 ALLSVSDRDSGPNGRVRCAVRPPS-PFGLVATFAGSYSLVLREALDRERVSEYEVEVRAE 426

Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
           DGG PP  ++  + + + D+ND+ P F     T    EN+  G  +  + A DPDE  N 
Sbjct: 427 DGGAPPLRASRGLRVPVSDVNDNAPAFAQAVYTVLARENNAAGAELARLWARDPDEAGNG 486

Query: 721 VVHYSI-KGGDDSNS--------FSLETRQGSDKAELVTMVDLDYESPR-KKYEL-VIRA 769
            V YS+ +GG  + S         S      ++   L  +  LDYE  +  ++E+  + A
Sbjct: 487 RVSYSVAEGGAGTGSGSGSGWRPASSYVSVDAESGRLRALRPLDYEELQVLQFEVRAVDA 546

Query: 770 ASPPLWNDVRVEILVTDVNDNAPVM 794
             PPL  +  V++ V D NDNAP +
Sbjct: 547 GEPPLCGNATVQLFVVDENDNAPAL 571



 Score =  189 bits (460), Expect = 1e-45
 Identities = 125/344 (36%), Positives = 184/344 (53%), Gaps = 15/344 (4%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           V++ +TD N+ AP F  A    S+ E +  G+   +  A+D+D+G NAQ++YSLS    +
Sbjct: 117 VEVEVTDINDNAPRFPAAYKNISIAESSLPGSRFPLEGASDADIGSNAQLSYSLSP---S 173

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
           E  A   +    N ++  +     LDRE++S + L +TA DGG P+L+ T  + ISV+D 
Sbjct: 174 EHFALDVKSPDDNLKSLFLVLTHPLDRESLSEHRLVLTASDGGRPALTGTVQLVISVLDA 233

Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDREEGSFVI 632
           NDN P F Q +Y   + EDA  GT V++V ATD DVG N    Y +       +  +F I
Sbjct: 234 NDNAPQFNQSVYKVQLPEDAAEGTLVARVAATDPDVGFNQEFSYSIVSSVPASQSDAFSI 293

Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692
           DP +G IR    LD E V  H+L+  A D GTPP S    V +++ D+ND+ P      L
Sbjct: 294 DPRTGEIRLTGPLDFEDVHQHELQIEARDKGTPPLSGHCSVILEVLDVNDNAPEVWVTSL 353

Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL-ETRQGSDKAELVTM 751
           +  + E++ +GT +  +   D D GPN  V  +++     + F L  T  GS    LV  
Sbjct: 354 SVPVPEDAALGTVVALLSVSDRDSGPNGRVRCAVR---PPSPFGLVATFAGS--YSLVLR 408

Query: 752 VDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792
             LD E    +YE+ +RA    +PPL     + + V+DVNDNAP
Sbjct: 409 EALDRERV-SEYEVEVRAEDGGAPPLRASRGLRVPVSDVNDNAP 451



 Score =  186 bits (454), Expect = 6e-45
 Identities = 147/527 (27%), Positives = 239/527 (45%), Gaps = 31/527 (5%)

Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDG-GSPS 236
           + G   A R  ++    +    +   SG + +   LD E++  +S    +R +     P 
Sbjct: 53  EAGEAEARRLRLVARGRRASVEVSGASGALVVSSRLDREELCGKSAPCALRLEVLLDRPL 112

Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
           R     + + + D+NDNAPRF  +    S++E+   G       A DAD G NA+L+Y++
Sbjct: 113 R--VFHVEVEVTDINDNAPRFPAAYKNISIAESSLPGSRFPLEGASDADIGSNAQLSYSL 170

Query: 297 TDKDYTGNVDLPITIDP-RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355
           +  ++   +D+    D  +S ++  +  LDRE+ ++++L++TA+DGG P  + T      
Sbjct: 171 SPSEHFA-LDVKSPDDNLKSLFLVLTHPLDRESLSEHRLVLTASDGGRPALTGTVQLVIS 229

Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFS 413
                     F    Y+V+L ED   GT V  + ATD D   +    Y I       +  
Sbjct: 230 VLDANDNAPQFNQSVYKVQLPEDAAEGTLVARVAATDPDVGFNQEFSYSIVSSVPASQSD 289

Query: 414 ITSQNGR-GLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFE 470
             S + R G I +  PLDF+   ++ L + A D G    S    V + + D N+ AP   
Sbjct: 290 AFSIDPRTGEIRLTGPLDFEDVHQHELQIEARDKGTPPLSGHCSVILEVLDVNDNAPEVW 349

Query: 471 NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
               +  V EDA +GT V ++S +D D G N ++  ++        VA     +      
Sbjct: 350 VTSLSVPVPEDAALGTVVALLSVSDRDSGPNGRVRCAVRPPSPFGLVATFAGSY------ 403

Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590
            ++   + LDRE +S Y + V A DGG P L  +  + + V DVNDN P F Q +YT   
Sbjct: 404 -SLVLREALDRERVSEYEVEVRAEDGGAPPLRASRGLRVPVSDVNDNAPAFAQAVYTVLA 462

Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKD-----------REEGSFV-IDPASGV 638
            E+   G  ++++ A D D   NGR+ Y +               R   S+V +D  SG 
Sbjct: 463 RENNAAGAELARLWARDPDEAGNGRVSYSVAEGGAGTGSGSGSGWRPASSYVSVDAESGR 522

Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685
           +R  + LD E +     +  A+D G PP      V + + D ND+ P
Sbjct: 523 LRALRPLDYEELQVLQFEVRAVDAGEPPLCGNATVQLFVVDENDNAP 569



 Score =  182 bits (442), Expect = 2e-43
 Identities = 139/505 (27%), Positives = 228/505 (45%), Gaps = 27/505 (5%)

Query: 92  IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151
           + G SGAL+  + LDRE++   +       +   + DR      + V + D NDN P+F 
Sbjct: 75  VSGASGALVVSSRLDREELCGKSA--PCALRLEVLLDRPLRVFHVEVEVTDINDNAPRFP 132

Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD--- 208
                +S+ E  S           A+DAD+G+N+ + Y++   +    F++D  S D   
Sbjct: 133 AAYKNISIAE--SSLPGSRFPLEGASDADIGSNAQLSYSL---SPSEHFALDVKSPDDNL 187

Query: 209 ----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
               + L   LD E +  +RLV+ A DGG P+ + T QL+I++ D NDNAP+F  S+++ 
Sbjct: 188 KSLFLVLTHPLDRESLSEHRLVLTASDGGRPALTGTVQLVISVLDANDNAPQFNQSVYKV 247

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
            + E+   G  + RV A D D G N E +Y++         D   +IDPR+G +  +G L
Sbjct: 248 QLPEDAAEGTLVARVAATDPDVGFNQEFSYSIVSSVPASQSD-AFSIDPRTGEIRLTGPL 306

Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
           D E   +++L + A D G PP S   +                     V + ED   GT 
Sbjct: 307 DFEDVHQHELQIEARDKGTPPLSGHCSVILEVLDVNDNAPEVWVTSLSVPVPEDAALGTV 366

Query: 385 VVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
           V  L+ +D D   + R+   +   +  G   + +  G   + + + LD ++   Y + V 
Sbjct: 367 VALLSVSDRDSGPNGRVRCAVRPPSPFG--LVATFAGSYSLVLREALDRERVSEYEVEVR 424

Query: 443 ATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
           A D G     A   +++ ++D N+ AP F  A YT    E+   G  +  + A D D   
Sbjct: 425 AEDGGAPPLRASRGLRVPVSDVNDNAPAFAQAVYTVLARENNAAGAELARLWARDPDEAG 484

Query: 501 NAQITYSL------SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554
           N +++YS+      +   S            ++ ++G +   + LD E +      V A 
Sbjct: 485 NGRVSYSVAEGGAGTGSGSGSGWRPASSYVSVDAESGRLRALRPLDYEELQVLQFEVRAV 544

Query: 555 DGGVPSLSDTTDVEISVVDVNDNEP 579
           D G P L     V++ VVD NDN P
Sbjct: 545 DAGEPPLCGNATVQLFVVDENDNAP 569



 Score =  174 bits (423), Expect = 3e-41
 Identities = 134/481 (27%), Positives = 216/481 (44%), Gaps = 48/481 (9%)

Query: 8   HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI---EL 64
           H ++ V D ND++P F       S+ E +  G+      A+D DIG NA++ Y++   E 
Sbjct: 116 HVEVEVTDINDNAPRFPAAYKNISIAESSLPGSRFPLEGASDADIGSNAQLSYSLSPSEH 175

Query: 65  VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS 124
              D  +P+D           ++ +F        L+    LDRE ++ + +++ A+D   
Sbjct: 176 FALDVKSPDD----------NLKSLF--------LVLTHPLDRESLSEHRLVLTASDGGR 217

Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184
           P    L+ T  + ++++D NDN PQF++  Y V + ED    +  ++A++ ATD DVG N
Sbjct: 218 PA---LTGTVQLVISVLDANDNAPQFNQSVYKVQLPED--AAEGTLVARVAATDPDVGFN 272

Query: 185 SAIRYAIIGGNTQMQ---FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
               Y+I+      Q   FSID  +G++ L   LD+E V  + L I A+D G+P  S   
Sbjct: 273 QEFSYSIVSSVPASQSDAFSIDPRTGEIRLTGPLDFEDVHQHELQIEARDKGTPPLSGHC 332

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
            +++ + DVNDNAP  + +     V E+  +G  +  +   D D G N  +   +     
Sbjct: 333 SVILEVLDVNDNAPEVWVTSLSVPVPEDAALGTVVALLSVSDRDSGPNGRVRCAVRPPSP 392

Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
            G   L  T       V     LDRE  ++Y++ V A DGG PP  A+            
Sbjct: 393 FG---LVATFAGSYSLVLREA-LDRERVSEYEVEVRAEDGGAPPLRASRGLRVPVSDVND 448

Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI----------TGGNTR 409
               F    Y V   E+   G  +  L A D DE  + R+ Y +          +G   R
Sbjct: 449 NAPAFAQAVYTVLARENNAAGAELARLWARDPDEAGNGRVSYSVAEGGAGTGSGSGSGWR 508

Query: 410 GRFSITSQNGR-GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYA 466
              S  S +   G +   +PLD+++ +     V A D+G       A VQ+ + D N+ A
Sbjct: 509 PASSYVSVDAESGRLRALRPLDYEELQVLQFEVRAVDAGEPPLCGNATVQLFVVDENDNA 568

Query: 467 P 467
           P
Sbjct: 569 P 569



 Score = 54.0 bits (124), Expect = 6e-05
 Identities = 30/81 (37%), Positives = 43/81 (53%), Gaps = 4/81 (4%)

Query: 271 PIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA 330
           P G  + +++A DAD G NA L Y + +    G    P  +   SG V T+  L+     
Sbjct: 622 PAGQVVAKIRAVDADSGYNAWLRYELREPRGEG----PFRVGLYSGEVSTARALEEADGP 677

Query: 331 KYQLLVTATDGGDPPRSATAT 351
           + +LL+   D G+PPRSATAT
Sbjct: 678 RQRLLIVVRDHGEPPRSATAT 698



 Score = 52.4 bits (120), Expect = 2e-04
 Identities = 28/78 (35%), Positives = 43/78 (55%)

Query: 170 VIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA 229
           V+AKI+A DAD G N+ +RY +     +  F +   SG+VS  + L+       RL+I  
Sbjct: 626 VVAKIRAVDADSGYNAWLRYELREPRGEGPFRVGLYSGEVSTARALEEADGPRQRLLIVV 685

Query: 230 QDGGSPSRSNTTQLLINI 247
           +D G P RS T  L +++
Sbjct: 686 RDHGEPPRSATATLSVSL 703



 Score = 49.2 bits (112), Expect = 0.002
 Identities = 29/84 (34%), Positives = 43/84 (51%), Gaps = 1/84 (1%)

Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653
           A  G  V+++ A DAD G N  + YEL  + R EG F +   SG + T +AL+       
Sbjct: 621 APAGQVVAKIRAVDADSGYNAWLRYELR-EPRGEGPFRVGLYSGEVSTARALEEADGPRQ 679

Query: 654 DLKAVAIDGGTPPQSSTVIVHIKI 677
            L  V  D G PP+S+T  + + +
Sbjct: 680 RLLIVVRDHGEPPRSATATLSVSL 703



 Score = 38.3 bits (85), Expect = 3.0
 Identities = 25/92 (27%), Positives = 40/92 (43%), Gaps = 7/92 (7%)

Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
           AP G  V  + A D+D G NA + Y L            +  F +   +G ++T + L+ 
Sbjct: 621 APAGQVVAKIRAVDADSGYNAWLRYELRE-------PRGEGPFRVGLYSGEVSTARALEE 673

Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
                  L +  RD G P  S T  + +S+V+
Sbjct: 674 ADGPRQRLLIVVRDHGEPPRSATATLSVSLVE 705


>UniRef50_O93508 Cluster: Paraxial protocadherin; n=6; Danio
           rerio|Rep: Paraxial protocadherin - Danio rerio
           (Zebrafish) (Brachydanio rerio)
          Length = 950

 Score =  200 bits (487), Expect = 6e-49
 Identities = 160/566 (28%), Positives = 263/566 (46%), Gaps = 37/566 (6%)

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           I ++D+ND++P+F  +     +SE+ P+        A D D G N   +Y ++   +   
Sbjct: 113 IEVKDINDHSPQFTRNETHLDISEDAPLNSRFPLDVAVDHDVGDNYIQSYHISHNSHFV- 171

Query: 305 VDLPITID-PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
           V++    D  +S  +     LDRET+  Y + VTATDGG P +S + T            
Sbjct: 172 VEVSTREDGEKSAELVLIKSLDRETEDFYTIEVTATDGGAPQKSGSTTLYIRVLDFNDNS 231

Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR--- 420
             F     +VEL+ED P G+ V+ + A D D    ++ EI  G   G  S  ++  +   
Sbjct: 232 PTFEHSSLKVELSEDSPIGSRVLKVHAFDPDAG--INGEIVYGFVEGSPSEVTRVFQIDL 289

Query: 421 --GLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTA 476
             G +T+   +D++ ++ Y L + A+D G  S   T    ++I D N+ AP     P T+
Sbjct: 290 ISGEVTLKDIVDYETKKSYELHIQASDLGANSVSSTCRAIVDIIDVNDNAPEIIIKPMTS 349

Query: 477 S------VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
           +      + E A   + V ++S +D D G N  +  SL      E   H   Q   +  T
Sbjct: 350 TSDGVAFITEAAAEESFVALISTSDKDSGPNGYVRTSL------EGHEHFKLQQAYS-DT 402

Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590
             I T   LDRE++S Y LTV + D G P         I + D NDN P+F + +Y  ++
Sbjct: 403 FMIITTTTLDRESISEYNLTVISEDLGTPPFKTVKHYTIRITDENDNPPLFSKSIYDVSV 462

Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV-----IDPASGVIRTNKAL 645
           +E+ + G+ ++ V A D D G NG++ Y L      +GS +     +DP SG + T ++ 
Sbjct: 463 IENNIPGSYMTTVVARDLDAGKNGKVSYSLVESKAPDGSSISTFVSVDPHSGSLYTLRSF 522

Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS-P----PVFESDCLTFYISENS 700
           D E++        A D G P  SST ++ +++ D ND+ P    PV  ++     I  N+
Sbjct: 523 DFETLKDVQFSVKATDKGFPSLSSTTLIQVRVVDDNDNFPYFTYPVLRNNSAEIPIPMNA 582

Query: 701 PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760
             G    ++ A D D G N+ ++Y I   D++  FS++   G  +  L   +        
Sbjct: 583 NTGYLALKVAAKDEDSGINSELNYHIL-EDEAKLFSIDKNTG--EIILKRKLTASCGEIL 639

Query: 761 KKYELVIRAASPPLWNDVRVEILVTD 786
           + Y  V+  A  PL +   +  +VTD
Sbjct: 640 QIYVSVVDGAREPLSSSANIRFIVTD 665



 Score =  195 bits (475), Expect = 2e-47
 Identities = 167/602 (27%), Positives = 254/602 (42%), Gaps = 27/602 (4%)

Query: 97  GALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT 156
           G L     +DREK+ + +     T      S        + + + D ND+ PQF+     
Sbjct: 72  GLLTVGEVIDREKLCQRSPQCLITFDVVAFSKEKFQLIHVEIEVKDINDHSPQFTRNETH 131

Query: 157 VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL-----SGDVSL 211
           + + ED  +  N       A D DVG N    Y I   N+     + +      S ++ L
Sbjct: 132 LDISEDAPL--NSRFPLDVAVDHDVGDNYIQSYHI-SHNSHFVVEVSTREDGEKSAELVL 188

Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271
           +K+LD E    Y + + A DGG+P +S +T L I + D NDN+P F  S  +  +SE+ P
Sbjct: 189 IKSLDRETEDFYTIEVTATDGGAPQKSGSTTLYIRVLDFNDNSPTFEHSSLKVELSEDSP 248

Query: 272 IGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK 331
           IG  +++V A+D D G+N E+ Y   +      V     ID  SG V     +D ET+  
Sbjct: 249 IGSRVLKVHAFDPDAGINGEIVYGFVEGS-PSEVTRVFQIDLISGEVTLKDIVDYETKKS 307

Query: 332 YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF----MPGQYE-VELAEDEPPGTPVV 386
           Y+L + A+D G    S+T                     M    + V    +       V
Sbjct: 308 YELHIQASDLGANSVSSTCRAIVDIIDVNDNAPEIIIKPMTSTSDGVAFITEAAAEESFV 367

Query: 387 TLTATDADEDNRLHYEITGGNTRGRFSI-TSQNGRGLITVAQPLDFKQERRYVLTVSATD 445
            L +T   +     Y  T       F +  + +   +I     LD +    Y LTV + D
Sbjct: 368 ALISTSDKDSGPNGYVRTSLEGHEHFKLQQAYSDTFMIITTTTLDRESISEYNLTVISED 427

Query: 446 SGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503
            G           I ITD N+  P+F  + Y  SV E+   G+ +  V A D D G N +
Sbjct: 428 LGTPPFKTVKHYTIRITDENDNPPLFSKSIYDVSVIENNIPGSYMTTVVARDLDAGKNGK 487

Query: 504 ITYSLSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
           ++YSL    S          FV ++P +G++ T +  D ET+     +V A D G PSLS
Sbjct: 488 VSYSLVE--SKAPDGSSISTFVSVDPHSGSLYTLRSFDFETLKDVQFSVKATDKGFPSLS 545

Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIME-----DALVGTSVSQVGATDADVGLNGRIH 617
            TT +++ VVD NDN P F   +   N  E     +A  G    +V A D D G+N  ++
Sbjct: 546 STTLIQVRVVDDNDNFPYFTYPVLRNNSAEIPIPMNANTGYLALKVAAKDEDSGINSELN 605

Query: 618 YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
           Y +   + E   F ID  +G I   + L         +    +DG   P SS+  +   +
Sbjct: 606 YHI--LEDEAKLFSIDKNTGEIILKRKLTASCGEILQIYVSVVDGAREPLSSSANIRFIV 663

Query: 678 ED 679
            D
Sbjct: 664 TD 665



 Score =  188 bits (457), Expect = 3e-45
 Identities = 150/535 (28%), Positives = 248/535 (46%), Gaps = 33/535 (6%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSI-TSQNGR--G 421
           F   +  ++++ED P  +      A D D  DN +       N+     + T ++G    
Sbjct: 125 FTRNETHLDISEDAPLNSRFPLDVAVDHDVGDNYIQSYHISHNSHFVVEVSTREDGEKSA 184

Query: 422 LITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVF 479
            + + + LD + E  Y + V+ATD G   +S +  + I + D N+ +P FE++     + 
Sbjct: 185 ELVLIKSLDRETEDFYTIEVTATDGGAPQKSGSTTLYIRVLDFNDNSPTFEHSSLKVELS 244

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           ED+PIG+ VL V A D D GIN +I Y       +E      + F I+  +G +T   ++
Sbjct: 245 EDSPIGSRVLKVHAFDPDAGINGEIVYGFVEGSPSEVT----RVFQIDLISGEVTLKDIV 300

Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP--VFKQQLYTAN----IMED 593
           D ET   Y L + A D G  S+S T    + ++DVNDN P  + K    T++    I E 
Sbjct: 301 DYETKKSYELHIQASDLGANSVSSTCRAIVDIIDVNDNAPEIIIKPMTSTSDGVAFITEA 360

Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653
           A   + V+ +  +D D G NG +   L+  +  +          +I T   LDRES++ +
Sbjct: 361 AAEESFVALISTSDKDSGPNGYVRTSLEGHEHFKLQQAYSDTFMIITTT-TLDRESISEY 419

Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713
           +L  ++ D GTPP  +     I+I D ND+PP+F        + EN+  G+ +  + A D
Sbjct: 420 NLTVISEDLGTPPFKTVKHYTIRITDENDNPPLFSKSIYDVSVIENNIPGSYMTTVVARD 479

Query: 714 PDEGPNAVVHYSI--KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771
            D G N  V YS+      D +S S           L T+   D+E+  K  +  ++A  
Sbjct: 480 LDAGKNGKVSYSLVESKAPDGSSISTFVSVDPHSGSLYTLRSFDFET-LKDVQFSVKATD 538

Query: 772 ---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC-FPVGPFG-----RVPAYDAD 822
              P L +   +++ V D NDN P    + ++ NN  +   P+         +V A D D
Sbjct: 539 KGFPSLSSTTLIQVRVVDDNDNFPYFT-YPVLRNNSAEIPIPMNANTGYLALKVAAKDED 597

Query: 823 --VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE 875
             +  +L Y IL  + A L  +++ TG + L  +L  +  ++  + VSV DG  E
Sbjct: 598 SGINSELNYHILE-DEAKLFSIDKNTGEIILKRKLTASCGEILQIYVSVVDGARE 651



 Score =  184 bits (447), Expect = 4e-44
 Identities = 165/595 (27%), Positives = 254/595 (42%), Gaps = 56/595 (9%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           IH +I V D NDHSP F   +    + E A   +      A D D+G N    Y I    
Sbjct: 109 IHVEIEVKDINDHSPQFTRNETHLDISEDAPLNSRFPLDVAVDHDVGDNYIQSYHIS--- 165

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASP 125
                              V+   R DG +S  L+   SLDRE    YT+ V ATD  +P
Sbjct: 166 -------------HNSHFVVEVSTREDGEKSAELVLIKSLDRETEDFYTIEVTATDGGAP 212

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
              + S + T+++ ++D NDN P F   +  V + ED  +     + K+ A D D G N 
Sbjct: 213 ---QKSGSTTLYIRVLDFNDNSPTFEHSSLKVELSEDSPIGSR--VLKVHAFDPDAGING 267

Query: 186 AIRYAIIGGNTQ---MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
            I Y  + G+       F ID +SG+V+L   +DYE  +SY L I+A D G+ S S+T +
Sbjct: 268 EIVYGFVEGSPSEVTRVFQIDLISGEVTLKDIVDYETKKSYELHIQASDLGANSVSSTCR 327

Query: 243 LLINIRDVNDNAPRFY------TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
            +++I DVNDNAP         TS     ++E       +  +   D D G N    Y  
Sbjct: 328 AIVDIIDVNDNAPEIIIKPMTSTSDGVAFITEAAAEESFVALISTSDKDSGPNG---YVR 384

Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
           T  +   +  L       +  + T+  LDRE+ ++Y L V + D G PP           
Sbjct: 385 TSLEGHEHFKLQQAYSD-TFMIITTTTLDRESISEYNLTVISEDLGTPPFKTVKHYTIRI 443

Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSI 414
                    F    Y+V + E+  PG+ + T+ A D D  ++ ++ Y +         SI
Sbjct: 444 TDENDNPPLFSKSIYDVSVIENNIPGSYMTTVVARDLDAGKNGKVSYSLVESKAPDGSSI 503

Query: 415 TS----QNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDAN-NYA- 466
           ++        G +   +  DF+  +    +V ATD G    S T ++Q+ + D N N+  
Sbjct: 504 STFVSVDPHSGSLYTLRSFDFETLKDVQFSVKATDKGFPSLSSTTLIQVRVVDDNDNFPY 563

Query: 467 ---PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523
              PV  N      +  +A  G   L V+A D D GIN+++ Y +   + +EA     + 
Sbjct: 564 FTYPVLRNNSAEIPIPMNANTGYLALKVAAKDEDSGINSELNYHI---LEDEA-----KL 615

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578
           F I+  TG I   + L         + V+  DG    LS + ++   V D    E
Sbjct: 616 FSIDKNTGEIILKRKLTASCGEILQIYVSVVDGAREPLSSSANIRFIVTDTGAQE 670



 Score =  149 bits (362), Expect = 8e-34
 Identities = 147/546 (26%), Positives = 238/546 (43%), Gaps = 49/546 (8%)

Query: 377 EDEPPGTPVVTLTAT---DADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD--- 430
           E++ PGT +  L+     D  ED    ++    +      I  +   GL+TV + +D   
Sbjct: 28  EEDAPGTEIGNLSQDLKIDPSEDPETSFKFIQTSNS---IIDMRQMDGLLTVGEVIDREK 84

Query: 431 -FKQERRYVLTVSATD-SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
             ++  + ++T      S  +     V+I + D N+++P F        + EDAP+ +  
Sbjct: 85  LCQRSPQCLITFDVVAFSKEKFQLIHVEIEVKDINDHSPQFTRNETHLDISEDAPLNSRF 144

Query: 489 LVVSATDSDVGINAQITYSLS--SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
            +  A D DVG N   +Y +S  S    E     D +     ++  +   K LDRET   
Sbjct: 145 PLDVAVDHDVGDNYIQSYHISHNSHFVVEVSTREDGE-----KSAELVLIKSLDRETEDF 199

Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
           Y + VTA DGG P  S +T + I V+D NDN P F+       + ED+ +G+ V +V A 
Sbjct: 200 YTIEVTATDGGAPQKSGSTTLYIRVLDFNDNSPTFEHSSLKVELSEDSPIGSRVLKVHAF 259

Query: 607 DADVGLNGRIHYELDPKDREEGS--FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
           D D G+NG I Y        E +  F ID  SG +     +D E+  +++L   A D G 
Sbjct: 260 DPDAGINGEIVYGFVEGSPSEVTRVFQIDLISGEVTLKDIVDYETKKSYELHIQASDLGA 319

Query: 665 PPQSSTVIVHIKIEDINDSPP-------VFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
              SST    + I D+ND+ P          SD + F I+E +   + +  I   D D G
Sbjct: 320 NSVSSTCRAIVDIIDVNDNAPEIIIKPMTSTSDGVAF-ITEAAAEESFVALISTSDKDSG 378

Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPL 774
           PN  V  S++G +    F L+ +  SD   ++T   LD ES   +Y L + +    +PP 
Sbjct: 379 PNGYVRTSLEGHE---HFKLQ-QAYSDTFMIITTTTLDRES-ISEYNLTVISEDLGTPPF 433

Query: 775 WNDVRVEILVTDVNDNAPVMK----DFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYR 830
                  I +TD NDN P+      D  +I NN    +      R    DA    K+ Y 
Sbjct: 434 KTVKHYTIRITDENDNPPLFSKSIYDVSVIENNIPGSYMTTVVAR--DLDAGKNGKVSYS 491

Query: 831 IL-----SGNN-ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLS 883
           ++      G++ +  + ++  +GS+      +    K     V  TD G   + +   + 
Sbjct: 492 LVESKAPDGSSISTFVSVDPHSGSLYTLRSFDFETLKDVQFSVKATDKGFPSLSSTTLIQ 551

Query: 884 VRLITE 889
           VR++ +
Sbjct: 552 VRVVDD 557


>UniRef50_UPI0000660F9A Cluster: Homolog of Brachydanio rerio
           "Cadherin-related neuronal receptor variable 7.; n=1;
           Takifugu rubripes|Rep: Homolog of Brachydanio rerio
           "Cadherin-related neuronal receptor variable 7. -
           Takifugu rubripes
          Length = 718

 Score =  199 bits (486), Expect = 8e-49
 Identities = 168/583 (28%), Positives = 264/583 (45%), Gaps = 56/583 (9%)

Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG- 194
           I V ++D NDN PQF      + + E  +       +   A D D+G+NS   Y +    
Sbjct: 21  IEVELLDINDNAPQFRRDAIHLDISE--ATPRGERFSLSNAVDPDIGSNSVKTYQLSEND 78

Query: 195 --NTQMQFSIDSLS-GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251
             N ++Q   +     D+ L  TLD EQ   + L++ A DGG P+RS T  +++++ D N
Sbjct: 79  YFNIEVQTGREGTKFADLILKTTLDREQQSVHNLILTAVDGGKPARSGTASVIVHVMDTN 138

Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY---------TMTDK--- 299
           DN+P F    +   + EN PIG  ++ + A D DEG N++LTY         T+  +   
Sbjct: 139 DNSPTFDQINYNLEIMENSPIGSLVIHLNATDLDEGSNSDLTYSYNLGLDVKTLNQRKMR 198

Query: 300 -DYTGNVDLPITIDPRSGWVYTSGQLDRE----TQAK-YQLLVTATDGGDPPRSATATXX 353
            D   N    + ++  +G +Y   ++DRE    T+A  Y  L    D   P R       
Sbjct: 199 LDIIANKKY-LDVNKETGELYVVEKIDREYICSTKASCYLKLEVILD--SPVR--IFNIE 253

Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS 413
                       F      ++++E  P G       A D D  +    +    +    F+
Sbjct: 254 VEILDINDNAPQFRRDIIHLDISEATPRGERFSLSNAVDPDVGSN-SVKTYYLSESEYFN 312

Query: 414 ITSQNGR-----GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYA 466
           I  Q GR       + + + LD +Q+  + L ++A D G   RS TA V + + D N+ +
Sbjct: 313 IEVQTGRDGSKFSELILKRALDREQQSVHNLILTAVDGGKPARSGTASVIVRVLDTNDNS 372

Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
           P F+ + Y   + E++PIG+ V+ ++ATD D G N+ +TYS S   + +      + F +
Sbjct: 373 PTFDKSNYNLEIMENSPIGSLVIHLNATDLDEGSNSDLTYSYSLYTAEKT----QETFYL 428

Query: 527 NPQTGAITTN--------KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578
           NP TG IT          K+ D E    +L  + ARD G P LS    V I +VD NDN 
Sbjct: 429 NPSTGEITVKGLLNYEDFKIYDMEIEKEFLFHIEARDSGSPPLSSNVSVHIIIVDQNDNA 488

Query: 579 PVFKQQLYT-ANIMEDAL-----VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632
           PV         +++E+ +      G+ V++V A D D   N RI Y+L  +  +   F +
Sbjct: 489 PVIVSPWRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQL-LQVTDATLFSL 547

Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675
           D  +G IRT +           L  VA D G P  S+TV + +
Sbjct: 548 DQYNGEIRTMRMFSYRDPRHQRLVVVAKDNGNPALSATVTIKL 590



 Score =  174 bits (424), Expect = 3e-41
 Identities = 163/602 (27%), Positives = 270/602 (44%), Gaps = 67/602 (11%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ +LD ND++P F        + E    G       A D DIG N+   Y  +L   D 
Sbjct: 22  EVELLDINDNAPQFRRDAIHLDISEATPRGERFSLSNAVDPDIGSNSVKTY--QLSENDY 79

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            N E            VQ   R   +   L+ + +LDRE+ + + +++ A D   P    
Sbjct: 80  FNIE------------VQ-TGREGTKFADLILKTTLDREQQSVHNLILTAVDGGKPAR-- 124

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            S TA++ V+++D NDN P F +  Y + + E+  +    ++  + ATD D G+NS + Y
Sbjct: 125 -SGTASVIVHVMDTNDNSPTFDQINYNLEIMENSPI--GSLVIHLNATDLDEGSNSDLTY 181

Query: 190 AI-----IGGNTQMQFSIDSL-----------SGDVSLVKTLDYEQVRSYRLVIRAQ-DG 232
           +      +    Q +  +D +           +G++ +V+ +D E + S +     + + 
Sbjct: 182 SYNLGLDVKTLNQRKMRLDIIANKKYLDVNKETGELYVVEKIDREYICSTKASCYLKLEV 241

Query: 233 GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292
              S      + + I D+NDNAP+F   +    +SE  P G       A D D G N+  
Sbjct: 242 ILDSPVRIFNIEVEILDINDNAPQFRRDIIHLDISEATPRGERFSLSNAVDPDVGSNSVK 301

Query: 293 TYTMTDKDYTGNVDLPITID-PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
           TY +++ +Y  N+++    D  +   +     LDRE Q+ + L++TA DGG P RS TA+
Sbjct: 302 TYYLSESEYF-NIEVQTGRDGSKFSELILKRALDREQQSVHNLILTAVDGGKPARSGTAS 360

Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE----DNRLHYEI-TGG 406
                         F    Y +E+ E+ P G+ V+ L ATD DE    D    Y + T  
Sbjct: 361 VIVRVLDTNDNSPTFDKSNYNLEIMENSPIGSLVIHLNATDLDEGSNSDLTYSYSLYTAE 420

Query: 407 NTRGRFSITSQNG----RGLITVA--QPLDFKQERRYVLTVSATDSGG--RSDTAMVQIN 458
            T+  F +    G    +GL+     +  D + E+ ++  + A DSG    S    V I 
Sbjct: 421 KTQETFYLNPSTGEITVKGLLNYEDFKIYDMEIEKEFLFHIEARDSGSPPLSSNVSVHII 480

Query: 459 ITDANNYAPVFENAPYTA--SVFED-----APIGTTVLVVSATDSDVGINAQITYSLSSE 511
           I D N+ APV   +P+ A  SV E+        G+ V  V A D D   N++ITY L  +
Sbjct: 481 IVDQNDNAPVIV-SPWRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQL-LQ 538

Query: 512 ISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571
           +++  +      F ++   G I T ++          L V A+D G P+LS T  +++S 
Sbjct: 539 VTDATL------FSLDQYNGEIRTMRMFSYRDPRHQRLVVVAKDNGNPALSATVTIKLST 592

Query: 572 VD 573
           V+
Sbjct: 593 VE 594



 Score =  167 bits (406), Expect = 4e-39
 Identities = 161/599 (26%), Positives = 272/599 (45%), Gaps = 61/599 (10%)

Query: 373 VELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGR-----GLITV 425
           ++++E  P G       A D D   ++   Y+++  +    F+I  Q GR       + +
Sbjct: 42  LDISEATPRGERFSLSNAVDPDIGSNSVKTYQLSENDY---FNIEVQTGREGTKFADLIL 98

Query: 426 AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
              LD +Q+  + L ++A D G   RS TA V +++ D N+ +P F+   Y   + E++P
Sbjct: 99  KTTLDREQQSVHNLILTAVDGGKPARSGTASVIVHVMDTNDNSPTFDQINYNLEIMENSP 158

Query: 484 IGTTVLVVSATDSDVGINAQITYS----LSSEISNEAVAHHD-----QQFVINPQTGAIT 534
           IG+ V+ ++ATD D G N+ +TYS    L  +  N+     D     +   +N +TG + 
Sbjct: 159 IGSLVIHLNATDLDEGSNSDLTYSYNLGLDVKTLNQRKMRLDIIANKKYLDVNKETGELY 218

Query: 535 TNKLLDRETM-----SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589
             + +DRE +     S YL      D  V   +    +E+ ++D+NDN P F++ +   +
Sbjct: 219 VVEKIDREYICSTKASCYLKLEVILDSPVRIFN----IEVEILDINDNAPQFRRDIIHLD 274

Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG-------VIRTN 642
           I E    G   S   A D DVG N    Y L     E   F I+  +G        +   
Sbjct: 275 ISEATPRGERFSLSNAVDPDVGSNSVKTYYLS----ESEYFNIEVQTGRDGSKFSELILK 330

Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
           +ALDRE  + H+L   A+DGG P +S T  V +++ D ND+ P F+       I ENSPI
Sbjct: 331 RALDREQQSVHNLILTAVDGGKPARSGTASVIVRVLDTNDNSPTFDKSNYNLEIMENSPI 390

Query: 703 GTTIGEIRAHDPDEGPNAVVHYSIK---GGDDSNSFSLETRQGSDKAE-LVTMVDLD-YE 757
           G+ +  + A D DEG N+ + YS           +F L    G    + L+   D   Y+
Sbjct: 391 GSLVIHLNATDLDEGSNSDLTYSYSLYTAEKTQETFYLNPSTGEITVKGLLNYEDFKIYD 450

Query: 758 SPRKK---YELVIR-AASPPLWNDVRVEILVTDVNDNAPVM-----KDFQIIFNNYKDCF 808
              +K   + +  R + SPPL ++V V I++ D NDNAPV+         ++        
Sbjct: 451 MEIEKEFLFHIEARDSGSPPLSSNVSVHIIIVDQNDNAPVIVSPWRAQGSVVEEKIPRST 510

Query: 809 PVGPF-GRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATM 865
             G    +V A D D     ++ Y++L   +A L  L++  G +      +   P+   +
Sbjct: 511 DKGSLVAKVIALDVDSVHNSRITYQLLQVTDATLFSLDQYNGEIRTMRMFSYRDPRHQRL 570

Query: 866 EVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAE-QFLSPLLGFFIDGLAAI 923
            V   D  N   +   ++++L T E  + + +  L ++  E    S L  + + GL ++
Sbjct: 571 VVVAKDNGNPALS-ATVTIKLSTVETAVKAYS-DLTEVPLEYDIFSDLNLYLVIGLGSV 627



 Score =  160 bits (388), Expect = 6e-37
 Identities = 128/496 (25%), Positives = 216/496 (43%), Gaps = 37/496 (7%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIEL-VTADT 69
           ++V+D ND+SP F+   Y   + E +  G+ V+ L ATD D G N+++ Y+  L +   T
Sbjct: 132 VHVMDTNDNSPTFDQINYNLEIMENSPIGSLVIHLNATDLDEGSNSDLTYSYNLGLDVKT 191

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
           LN              +     ++  +G L     +DRE +   +       +   + D 
Sbjct: 192 LNQRKMRLDIIANKKYLD----VNKETGELYVVEKIDREYIC--STKASCYLKLEVILDS 245

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
                 I V I+D NDN PQF      + + E  +       +   A D DVG+NS   Y
Sbjct: 246 PVRIFNIEVEILDINDNAPQFRRDIIHLDISE--ATPRGERFSLSNAVDPDVGSNSVKTY 303

Query: 190 AIIGG---NTQMQFSID-SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
            +      N ++Q   D S   ++ L + LD EQ   + L++ A DGG P+RS T  +++
Sbjct: 304 YLSESEYFNIEVQTGRDGSKFSELILKRALDREQQSVHNLILTAVDGGKPARSGTASVIV 363

Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-N 304
            + D NDN+P F  S +   + EN PIG  ++ + A D DEG N++LTY+ +   YT   
Sbjct: 364 RVLDTNDNSPTFDKSNYNLEIMENSPIGSLVIHLNATDLDEGSNSDLTYSYS--LYTAEK 421

Query: 305 VDLPITIDPRSGWVYTSGQL--------DRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
                 ++P +G +   G L        D E + ++   + A D G PP S+  +     
Sbjct: 422 TQETFYLNPSTGEITVKGLLNYEDFKIYDMEIEKEFLFHIEARDSGSPPLSSNVSVHIII 481

Query: 357 XXXXXXXXXFM-PGQYEVELAEDEPP-----GTPVVTLTATDAD--EDNRLHYEITGGNT 408
                     + P + +  + E++ P     G+ V  + A D D   ++R+ Y++     
Sbjct: 482 VDQNDNAPVIVSPWRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQLLQVTD 541

Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468
              FS+   NG   I   +   ++  R   L V A D+G  + +A V I ++        
Sbjct: 542 ATLFSLDQYNGE--IRTMRMFSYRDPRHQRLVVVAKDNGNPALSATVTIKLSTVETAVKA 599

Query: 469 FEN---APYTASVFED 481
           + +    P    +F D
Sbjct: 600 YSDLTEVPLEYDIFSD 615



 Score =  130 bits (315), Expect = 4e-28
 Identities = 119/438 (27%), Positives = 182/438 (41%), Gaps = 30/438 (6%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           +++ + D N+ AP F        + E  P G    + +A D D+G N+  TY LS    N
Sbjct: 21  IEVELLDINDNAPQFRRDAIHLDISEATPRGERFSLSNAVDPDIGSNSVKTYQLS---EN 77

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
           +      Q      +   +     LDRE  S + L +TA DGG P+ S T  V + V+D 
Sbjct: 78  DYFNIEVQTGREGTKFADLILKTTLDREQQSVHNLILTAVDGGKPARSGTASVIVHVMDT 137

Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE----LDPKDREEGSF 630
           NDN P F Q  Y   IME++ +G+ V  + ATD D G N  + Y     LD K   +   
Sbjct: 138 NDNSPTFDQINYNLEIMENSPIGSLVIHLNATDLDEGSNSDLTYSYNLGLDVKTLNQRKM 197

Query: 631 VID-----------PASGVIRTNKALDRESVATHDLKA-VAIDGGTPPQSSTVIVHIKIE 678
            +D             +G +   + +DRE + +      + ++           + ++I 
Sbjct: 198 RLDIIANKKYLDVNKETGELYVVEKIDREYICSTKASCYLKLEVILDSPVRIFNIEVEIL 257

Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738
           DIND+ P F  D +   ISE +P G       A DPD G N+V  Y +   +  N     
Sbjct: 258 DINDNAPQFRRDIIHLDISEATPRGERFSLSNAVDPDVGSNSVKTYYLSESEYFNIEVQT 317

Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMK 795
            R GS  +EL+    LD E  +  + L++ A     P       V + V D NDN+P   
Sbjct: 318 GRDGSKFSELILKRALDREQ-QSVHNLILTAVDGGKPARSGTASVIVRVLDTNDNSPTFD 376

Query: 796 DFQIIFNNYKDCFPVGPFG-RVPAYDADVTDK----LQYRILSGNNA-NLILLNETTGSM 849
                    ++  P+G     + A D D          Y + +         LN +TG +
Sbjct: 377 KSNYNLEIMENS-PIGSLVIHLNATDLDEGSNSDLTYSYSLYTAEKTQETFYLNPSTGEI 435

Query: 850 TLSPQLNTNVPKLATMEV 867
           T+   LN    K+  ME+
Sbjct: 436 TVKGLLNYEDFKIYDMEI 453



 Score =  105 bits (253), Expect = 1e-20
 Identities = 86/281 (30%), Positives = 130/281 (46%), Gaps = 28/281 (9%)

Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625
           ++E+ ++D+NDN P F++     +I E    G   S   A D D+G N    Y+L   D 
Sbjct: 20  NIEVELLDINDNAPQFRRDAIHLDISEATPRGERFSLSNAVDPDIGSNSVKTYQLSENDY 79

Query: 626 -----EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680
                + G      A  +++T   LDRE  + H+L   A+DGG P +S T  V + + D 
Sbjct: 80  FNIEVQTGREGTKFADLILKT--TLDREQQSVHNLILTAVDGGKPARSGTASVIVHVMDT 137

Query: 681 NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD--------- 731
           ND+ P F+       I ENSPIG+ +  + A D DEG N+ + YS   G D         
Sbjct: 138 NDNSPTFDQINYNLEIMENSPIGSLVIHLNATDLDEGSNSDLTYSYNLGLDVKTLNQRKM 197

Query: 732 -----SNSFSLETRQGSDKAELVTMVDLDYESPRKK---YELVIRAASPPLWNDVRVEIL 783
                +N   L+  + + +  +V  +D +Y    K     +L +   SP    ++ VEIL
Sbjct: 198 RLDIIANKKYLDVNKETGELYVVEKIDREYICSTKASCYLKLEVILDSPVRIFNIEVEIL 257

Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADV 823
             D+NDNAP  +   II  +  +  P G  F    A D DV
Sbjct: 258 --DINDNAPQFRR-DIIHLDISEATPRGERFSLSNAVDPDV 295


>UniRef50_UPI0000DB7642 Cluster: PREDICTED: similar to Cad89D
           CG14900-PA; n=1; Apis mellifera|Rep: PREDICTED: similar
           to Cad89D CG14900-PA - Apis mellifera
          Length = 1730

 Score =  198 bits (483), Expect = 2e-48
 Identities = 222/831 (26%), Positives = 362/831 (43%), Gaps = 97/831 (11%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + V D NDH+P F    Y  +V E    G T+                   I  V  D  
Sbjct: 108 VYVEDINDHAPQFVDAPYHVTVDELTPVGVTIFR----------------GIHAVDGDKP 151

Query: 71  NPEDAXXXXXXXXXXVQDVFRID-GRSGALLTRASLDREKVAR-YTVLVKATDQASPVSD 128
           N  ++           +  F ++ G   AL+ R  +D +   R +T+++ ATD+ +P   
Sbjct: 152 NTPNSDVHYAIVKGNEEGKFSLESGHRTALILREPVDYDNGDREFTLVIAATDRGAPA-- 209

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKI------KATDADVG 182
           R ++T T+ + ++D++D  P+F+   Y   + E   + ++P+  +I      +ATD D  
Sbjct: 210 RTTNT-TVRITVLDNDDLDPKFTRDVYKAKIYEFYPMPEHPIFVRINFSTPIQATDRDRD 268

Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-----YRLVIRAQDGGSPSR 237
            ++ IRY I  GN +  F +D  +  + L + +D +  R+     + L I A    +P R
Sbjct: 269 IDAPIRYDIASGNERGFFHLDPKNATLYLKRAIDLDAERNLPSNTFTLQIHASQVDNPLR 328

Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297
           S   ++ + + D+NDN P F   L+  S+ EN+P G+S+++V A D D+G N +  Y + 
Sbjct: 329 SGVARVEVEVLDLNDNLPEFEVDLYNISIVENLPNGFSVLQVIARDRDQGENGQFDYELV 388

Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGGD---PPRSATATX 352
           D   +G      ++D RSGW+    Q  LDRE + + ++ V A +       PR+ +++ 
Sbjct: 389 DP--SG----AFSVDARSGWLTVRDQSVLDRERRDRLRMRVVAVEKRPSVVAPRNGSSSS 442

Query: 353 XXXXXXXXXXXX-----XFMPGQ-YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEI- 403
                             F+PG  YE+    D   GT +  + A D D   +  + Y + 
Sbjct: 443 SSVDVDVTLLDANDNNPIFVPGNLYELVARSDSKVGTVLGQVHAVDDDLGPNGMVRYRLQ 502

Query: 404 -TGGNTRGRFSITSQNGRGLITVAQ-PLDFKQERRYVLTVSATD-----SGGRSDTAMVQ 456
             G +T            G I+V++ P+    E R+ + V A D     S  R   A+V 
Sbjct: 503 KPGNSTARTPPFAVDEVTGTISVSESPI---LEGRHAIFVEAADQPANPSERRISLAVVT 559

Query: 457 INI--TDA-NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513
           +++  +D   +  P F  APY   V  + P+GT+V  +   D+ V  N  + Y L     
Sbjct: 560 VDVFRSDGPESLEPDFVGAPYEFWVGANVPVGTSVGQIRLNDA-VKTN-DLIYDLLHSY- 616

Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
            E V      F +  ++G IT  + ++R   S Y       D     L   T+V I VVD
Sbjct: 617 EEGV-----PFAVEERSGTITVVEEIERFDRSIYDFEAIVTD--ERDLMLITNVSIHVVD 669

Query: 574 VNDNEPVFKQQLYTANI-------MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE 626
            ND   +F +   TA +       M  A +G  + Q G   A         + ++ +D  
Sbjct: 670 PNDERGIFTRGTTTAPLVFHARENMAGAYIGQILPQNGTGSATPATR---FFIVNQQDVP 726

Query: 627 EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686
           + S   D   G +   K LDRE+   + +  +A    +        V + + D ND  P 
Sbjct: 727 DISITED---GALYAPKGLDREARQNYSITVIA---ESQRGVGVFQVSVIVLDENDHAPE 780

Query: 687 FESDCLTFYISENSPIGTTIG---EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
           F S      I+ENSP GT +     I A D DEG N    +++  G+ S  F +    G 
Sbjct: 781 FTSPLYEGRITENSPPGTKVNLSIPITATDKDEGINQNFVFTLH-GERSELFRIHPTTGL 839

Query: 744 DKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAPV 793
              E +    LD E+ R  Y   I A  +  L ++ R+ I VTDVNDN+PV
Sbjct: 840 VYFEGIDDRTLDREA-RANYSFTIVAKDNGGLTSESRLRITVTDVNDNSPV 889



 Score =  168 bits (409), Expect = 2e-39
 Identities = 202/761 (26%), Positives = 329/761 (43%), Gaps = 107/761 (14%)

Query: 13   VLDCNDHSPVFEMQQYEASVREGASSGTTV---LTLKATDQDIGKNAEVEYTIELVTADT 69
            VLD NDH+P F    YE  + E +  GT V   + + ATD+D G N    +T+    ++ 
Sbjct: 771  VLDENDHAPEFTSPLYEGRITENSPPGTKVNLSIPITATDKDEGINQNFVFTLHGERSEL 830

Query: 70   --LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
              ++P               D       S  ++ + +      +R  + V   +  SPV 
Sbjct: 831  FRIHPTTGLVYFEGIDDRTLDREARANYSFTIVAKDNGGLTSESRLRITVTDVNDNSPVF 890

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS-----------------VTDNPV 170
             R+       V + ++ D    F          +D S                 V +N  
Sbjct: 891  IRMIVLPEQGVRVSNEADTEASFEGNDVVADTADDTSGAGGDRAASGRRSPLLLVPENAT 950

Query: 171  IA----KIKATDADVGANSAIRYAII-----GGNTQMQ----------FSIDSLSGDVSL 211
            I     ++ A D D G N+AI Y+++     G  T ++          F +D  SG++S+
Sbjct: 951  IGAPIIRLLAEDRDEGTNAAITYSLVNETVSGDETVVESRLDTTNRRYFHLDPRSGEISV 1010

Query: 212  VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271
             + L  E   + R +  A+D G    + T +  I++ DVND+ P F  S +   V+E   
Sbjct: 1011 ARGLTAET--NVRFLALAKDPGGLFDNITVR--IHVVDVNDHPPSFDKSWYTFDVAEGTY 1066

Query: 272  IGYSIVRVQAYDADEGVNAELTYTMTDKDYTG--NVDLPITIDPRSGWVYTSGQLDRETQ 329
             GY++ RV+A DAD G NA +TY +T +D +G  NV     + P  G +  +G LDRET 
Sbjct: 1067 KGYTLGRVRAVDADHGRNANVTYELTTRDDSGVGNVSRIFEVGPGEGVIRVTGVLDRETV 1126

Query: 330  AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ-------------YEVELA 376
              ++LLVTA D G P  S+T                F                 Y   + 
Sbjct: 1127 PVHRLLVTARDNGVPRLSSTVEVEVNVLDVNDNPPVFHDYDEIEKDENGDPLPVYHASVL 1186

Query: 377  EDEPPGTPVVTLTATDAD----EDNRLHYEIT--GGNTRGRFSITSQNGRGLITVAQPLD 430
            E+ P G+ V+ + A D D     +  + +++   G   +  F+I S+ G  +ITV   LD
Sbjct: 1187 ENSPVGSRVIKVRADDTDFAGNGNGLILFDLNHPGKLEKQWFAIDSKEG--VITVVGDLD 1244

Query: 431  FKQERRYVLTVSATDSGGR---SDTAMVQINITDANN-------YAPVFENAPYTASVFE 480
            ++++R + L V+A+D G     + TA V + +++ ++        AP F++  Y   V E
Sbjct: 1245 YERQRSHRLVVTASDLGSPVSLTSTAAVIVAVSNEDDGEEGTTERAPTFKHRYYEVEVEE 1304

Query: 481  DAPIGTTVLVVS-ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
            +  +   V  +  A DSDV  +  + YS+   +++E  A   Q F I+P+ G++     +
Sbjct: 1305 NVEVPVLVARLELADDSDVR-DEHVRYSI---VADETKAR--QLFSIDPRNGSLYLTTGV 1358

Query: 540  DRETMSGYLLTVTA---RDG-GVPSL-------------SDTTDVEISVVDVNDNEPVFK 582
            DRE    Y   V     + G G+P +              +   V + V DVNDN P FK
Sbjct: 1359 DREVNDRYEAKVRVDRVKIGRGMPVMIYPVVGERLNGLAPNEARVVVRVKDVNDNAPRFK 1418

Query: 583  Q--QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640
               +   A +   A  G  V +V A D D G N  I Y++  ++ +   F IDP SG +R
Sbjct: 1419 SRGRPILAAVPTTAHYGYEVVKVEAEDPDEGANAEIRYQILGRE-DAPRFAIDPLSGQVR 1477

Query: 641  TNKALDRES--VATHDLKAVAIDGGTPPQSSTVIVHIKIED 679
            +  +  R++  V   D+KA    G    +SS   V + + D
Sbjct: 1478 SVASFGRDAGRVFGFDVKATDRRGAEDGRSSIANVFVYVLD 1518



 Score =  168 bits (408), Expect = 2e-39
 Identities = 161/555 (29%), Positives = 247/555 (44%), Gaps = 63/555 (11%)

Query: 377  EDEPPGTPVVTLTATDADEDNR-------LHYEITGGNTRGRFSITSQNGR--------G 421
            E+   G P++ L A D DE          ++  ++G  T     + + N R        G
Sbjct: 947  ENATIGAPIIRLLAEDRDEGTNAAITYSLVNETVSGDETVVESRLDTTNRRYFHLDPRSG 1006

Query: 422  LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
             I+VA+ L  +   R++    A D GG  D   V+I++ D N++ P F+ + YT  V E 
Sbjct: 1007 EISVARGLTAETNVRFLAL--AKDPGGLFDNITVRIHVVDVNDHPPSFDKSWYTFDVAEG 1064

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
               G T+  V A D+D G NA +TY L++   +  V +  + F + P  G I    +LDR
Sbjct: 1065 TYKGYTLGRVRAVDADHGRNANVTYELTTR-DDSGVGNVSRIFEVGPGEGVIRVTGVLDR 1123

Query: 542  ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ-------------QLYTA 588
            ET+  + L VTARD GVP LS T +VE++V+DVNDN PVF                +Y A
Sbjct: 1124 ETVPVHRLLVTARDNGVPRLSSTVEVEVNVLDVNDNPPVFHDYDEIEKDENGDPLPVYHA 1183

Query: 589  NIMEDALVGTSVSQVGATDADVGLNGR--IHYELD-PKDREEGSFVIDPASGVIRTNKAL 645
            +++E++ VG+ V +V A D D   NG   I ++L+ P   E+  F ID   GVI     L
Sbjct: 1184 SVLENSPVGSRVIKVRADDTDFAGNGNGLILFDLNHPGKLEKQWFAIDSKEGVITVVGDL 1243

Query: 646  DRESVATHDLKAVAIDGGTP---PQSSTVIVHIKIED-----INDSPPVFESDCLTFYIS 697
            D E   +H L   A D G+P     ++ VIV +  ED       +  P F+       + 
Sbjct: 1244 DYERQRSHRLVVTASDLGSPVSLTSTAAVIVAVSNEDDGEEGTTERAPTFKHRYYEVEVE 1303

Query: 698  ENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS--NSFSLETRQGS------------ 743
            EN  +   +  +   D  +  +  V YSI   +      FS++ R GS            
Sbjct: 1304 ENVEVPVLVARLELADDSDVRDEHVRYSIVADETKARQLFSIDPRNGSLYLTTGVDREVN 1363

Query: 744  DKAELVTMVD---LDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKD-FQI 799
            D+ E    VD   +    P   Y +V    +    N+ RV + V DVNDNAP  K   + 
Sbjct: 1364 DRYEAKVRVDRVKIGRGMPVMIYPVVGERLNGLAPNEARVVVRVKDVNDNAPRFKSRGRP 1423

Query: 800  IFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
            I          G    +V A D D     +++Y+IL   +A    ++  +G +       
Sbjct: 1424 ILAAVPTTAHYGYEVVKVEAEDPDEGANAEIRYQILGREDAPRFAIDPLSGQVRSVASFG 1483

Query: 857  TNVPKLATMEVSVTD 871
             +  ++   +V  TD
Sbjct: 1484 RDAGRVFGFDVKATD 1498



 Score =  166 bits (403), Expect = 9e-39
 Identities = 186/722 (25%), Positives = 313/722 (43%), Gaps = 69/722 (9%)

Query: 112 RYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVI 171
           ++ V+   +D+   V+  LS T    V + D ND+ PQF +  Y V+VDE ++     + 
Sbjct: 86  KFRVVCDYSDEKFIVTSHLSVT----VYVEDINDHAPQFVDAPYHVTVDE-LTPVGVTIF 140

Query: 172 AKIKATDADV--GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVK-TLDYEQ-VRSYRLVI 227
             I A D D     NS + YAI+ GN + +FS++S      +++  +DY+   R + LVI
Sbjct: 141 RGIHAVDGDKPNTPNSDVHYAIVKGNEEGKFSLESGHRTALILREPVDYDNGDREFTLVI 200

Query: 228 RAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP---------IGYSIVR 278
            A D G+P+R+  T + I + D +D  P+F   +++  + E  P         I +S   
Sbjct: 201 AATDRGAPARTTNTTVRITVLDNDDLDPKFTRDVYKAKIYEFYPMPEHPIFVRINFS-TP 259

Query: 279 VQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK-----YQ 333
           +QA D D  ++A + Y +     +GN      +DP++  +Y    +D + +       + 
Sbjct: 260 IQATDRDRDIDAPIRYDIA----SGNERGFFHLDPKNATLYLKRAIDLDAERNLPSNTFT 315

Query: 334 LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393
           L + A+   +P RS  A               F    Y + + E+ P G  V+ + A D 
Sbjct: 316 LQIHASQVDNPLRSGVARVEVEVLDLNDNLPEFEVDLYNISIVENLPNGFSVLQVIARDR 375

Query: 394 D--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS----- 446
           D  E+ +  YE+   +  G FS+ +++G   +     LD ++  R  + V A +      
Sbjct: 376 DQGENGQFDYELV--DPSGAFSVDARSGWLTVRDQSVLDRERRDRLRMRVVAVEKRPSVV 433

Query: 447 ---GGRSDTAMVQINIT--DANNYAPVF-ENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
               G S ++ V +++T  DAN+  P+F     Y      D+ +GT +  V A D D+G 
Sbjct: 434 APRNGSSSSSSVDVDVTLLDANDNNPIFVPGNLYELVARSDSKVGTVLGQVHAVDDDLGP 493

Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560
           N  + Y L    ++ A       F ++  TG I+ ++    E    + + V A D     
Sbjct: 494 NGMVRYRLQKPGNSTA---RTPPFAVDEVTGTISVSESPILE--GRHAIFVEAADQPANP 548

Query: 561 LSDTTDVEISVVDV--NDN----EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614
                 + +  VDV  +D     EP F    Y   +  +  VGTSV Q+   DA V  N 
Sbjct: 549 SERRISLAVVTVDVFRSDGPESLEPDFVGAPYEFWVGANVPVGTSVGQIRLNDA-VKTND 607

Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674
            I Y+L     E   F ++  SG I   + ++R   + +D +A+  D       + V +H
Sbjct: 608 LI-YDLLHSYEEGVPFAVEERSGTITVVEEIERFDRSIYDFEAIVTDERDLMLITNVSIH 666

Query: 675 IKIEDINDSPPVFESDC----LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD 730
             + D ND   +F        L F+  EN   G  IG+I   +          + I    
Sbjct: 667 --VVDPNDERGIFTRGTTTAPLVFHARENM-AGAYIGQILPQNGTGSATPATRFFIVNQQ 723

Query: 731 DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDN 790
           D    S+ T  G+    L     LD E+ R+ Y + + A S       +V ++V D ND+
Sbjct: 724 DVPDISI-TEDGA----LYAPKGLDREA-RQNYSITVIAESQRGVGVFQVSVIVLDENDH 777

Query: 791 AP 792
           AP
Sbjct: 778 AP 779



 Score =  150 bits (363), Expect = 6e-34
 Identities = 160/601 (26%), Positives = 262/601 (43%), Gaps = 74/601 (12%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ VLD ND+ P FE+  Y  S+ E   +G +VL + A D+D G+N + +Y  ELV    
Sbjct: 335 EVEVLDLNDNLPEFEVDLYNISIVENLPNGFSVLQVIARDRDQGENGQFDY--ELV---- 388

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR--ASLDREKVARYTVLVKATD-QASPV 126
            +P  A              F +D RSG L  R  + LDRE+  R  + V A + + S V
Sbjct: 389 -DPSGA--------------FSVDARSGWLTVRDQSVLDRERRDRLRMRVVAVEKRPSVV 433

Query: 127 SDR----LSSTATIHVNIIDDNDNYPQF-SEKTYTVSVDEDISVTDNPVIAKIKATDADV 181
           + R     SS+  + V ++D NDN P F     Y +    D  V    V+ ++ A D D+
Sbjct: 434 APRNGSSSSSSVDVDVTLLDANDNNPIFVPGNLYELVARSDSKV--GTVLGQVHAVDDDL 491

Query: 182 GANSAIRYAI-IGGNTQMQ---FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237
           G N  +RY +   GN+  +   F++D ++G +S+ ++   E  R    V  A    +PS 
Sbjct: 492 GPNGMVRYRLQKPGNSTARTPPFAVDEVTGTISVSESPILEG-RHAIFVEAADQPANPSE 550

Query: 238 SNTTQLLINIRDVNDNAPR-----FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292
              +  ++ +     + P      F  + ++  V  NVP+G S+ +++  DA +    +L
Sbjct: 551 RRISLAVVTVDVFRSDGPESLEPDFVGAPYEFWVGANVPVGTSVGQIRLNDAVK--TNDL 608

Query: 293 TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352
            Y +      G   +P  ++ RSG +    +++R  ++ Y      TD  D         
Sbjct: 609 IYDLLHSYEEG---VPFAVEERSGTITVVEEIERFDRSIYDFEAIVTDERD--LMLITNV 663

Query: 353 XXXXXXXXXXXXXFMPGQYEVEL---AEDEPPGTPVVTLTATD--ADEDNRLHYEITGGN 407
                        F  G     L   A +   G  +  +   +          + I    
Sbjct: 664 SIHVVDPNDERGIFTRGTTTAPLVFHARENMAGAYIGQILPQNGTGSATPATRFFIVNQQ 723

Query: 408 TRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAP 467
                SIT     G +   + LD +  + Y +TV A    G      V + + D N++AP
Sbjct: 724 DVPDISITED---GALYAPKGLDREARQNYSITVIAESQRG-VGVFQVSVIVLDENDHAP 779

Query: 468 VFENAPYTASVFEDAPIGTTV---LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524
            F +  Y   + E++P GT V   + ++ATD D GIN    ++L  E S        + F
Sbjct: 780 EFTSPLYEGRITENSPPGTKVNLSIPITATDKDEGINQNFVFTLHGERS--------ELF 831

Query: 525 VINPQTGAI----TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580
            I+P TG +      ++ LDRE  + Y  T+ A+D G   L+  + + I+V DVNDN PV
Sbjct: 832 RIHPTTGLVYFEGIDDRTLDREARANYSFTIVAKDNG--GLTSESRLRITVTDVNDNSPV 889

Query: 581 F 581
           F
Sbjct: 890 F 890



 Score =  139 bits (337), Expect = 9e-31
 Identities = 114/351 (32%), Positives = 173/351 (49%), Gaps = 43/351 (12%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +I+V+D NDH P F+   Y   V EG   G T+  ++A D D G+NA V Y  EL T D 
Sbjct: 1039 RIHVVDVNDHPPSFDKSWYTFDVAEGTYKGYTLGRVRAVDADHGRNANVTY--ELTTRD- 1095

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                            V  +F +    G +     LDRE V  + +LV A D   P   R
Sbjct: 1096 ----------DSGVGNVSRIFEVGPGEGVIRVTGVLDRETVPVHRLLVTARDNGVP---R 1142

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED--------ISVTDN-PV---IAKIKAT 177
            LSST  + VN++D NDN P F +    +  DE+         SV +N PV   + K++A 
Sbjct: 1143 LSSTVEVEVNVLDVNDNPPVFHDYD-EIEKDENGDPLPVYHASVLENSPVGSRVIKVRAD 1201

Query: 178  DADV--GANSAIRYAI-IGGNTQMQ-FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233
            D D     N  I + +   G  + Q F+IDS  G +++V  LDYE+ RS+RLV+ A D G
Sbjct: 1202 DTDFAGNGNGLILFDLNHPGKLEKQWFAIDSKEGVITVVGDLDYERQRSHRLVVTASDLG 1261

Query: 234  SP-SRSNTTQLLINIRDVND-------NAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD 285
            SP S ++T  +++ + + +D        AP F    ++  V ENV +   + R++  D  
Sbjct: 1262 SPVSLTSTAAVIVAVSNEDDGEEGTTERAPTFKHRYYEVEVEENVEVPVLVARLELADDS 1321

Query: 286  EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLV 336
            +  +  + Y++   D T    L  +IDPR+G +Y +  +DRE   +Y+  V
Sbjct: 1322 DVRDEHVRYSIV-ADETKARQL-FSIDPRNGSLYLTTGVDREVNDRYEAKV 1370



 Score =  134 bits (323), Expect = 4e-29
 Identities = 172/710 (24%), Positives = 283/710 (39%), Gaps = 68/710 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +I VLD +D  P F    Y+A + E        + ++           + ++  +   D 
Sbjct: 217 RITVLDNDDLDPKFTRDVYKAKIYEFYPMPEHPIFVR-----------INFSTPIQATDR 265

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRA-SLDREKVA---RYTVLVKATDQAS 124
               DA           +  F +D ++  L L RA  LD E+      +T+ + A+   +
Sbjct: 266 DRDIDAPIRYDIASGNERGFFHLDPKNATLYLKRAIDLDAERNLPSNTFTLQIHASQVDN 325

Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184
           P+    S  A + V ++D NDN P+F    Y +S+ E++   +   + ++ A D D G N
Sbjct: 326 PLR---SGVARVEVEVLDLNDNLPEFEVDLYNISIVENLP--NGFSVLQVIARDRDQGEN 380

Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIR-----------AQDGG 233
               Y ++  +    FS+D+ SG +++      ++ R  RL +R           A   G
Sbjct: 381 GQFDYELV--DPSGAFSVDARSGWLTVRDQSVLDRERRDRLRMRVVAVEKRPSVVAPRNG 438

Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN-VPIGYSIVRVQAYDADEGVNAEL 292
           S S S++  + + + D NDN P F      E V+ +   +G  + +V A D D G N  +
Sbjct: 439 SSS-SSSVDVDVTLLDANDNNPIFVPGNLYELVARSDSKVGTVLGQVHAVDDDLGPNGMV 497

Query: 293 TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352
            Y +     +     P  +D  +G +  S     E   ++ + V A D    P     + 
Sbjct: 498 RYRLQKPGNSTARTPPFAVDEVTGTISVSESPILE--GRHAIFVEAADQPANPSERRISL 555

Query: 353 XXXXXXXXXXXX------XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG 406
                              F+   YE  +  + P GT V  +   DA + N L Y++   
Sbjct: 556 AVVTVDVFRSDGPESLEPDFVGAPYEFWVGANVPVGTSVGQIRLNDAVKTNDLIYDLLHS 615

Query: 407 NTRG-RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNY 465
              G  F++  ++G   ITV + ++      Y      TD         V I++ D N+ 
Sbjct: 616 YEEGVPFAVEERSGT--ITVVEEIERFDRSIYDFEAIVTDERDLMLITNVSIHVVDPNDE 673

Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525
             +F     TA +   A        +       G     T S +       V   D   +
Sbjct: 674 RGIFTRGTTTAPLVFHARENMAGAYIGQILPQNG-----TGSATPATRFFIVNQQDVPDI 728

Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEPVFKQQ 584
              + GA+   K LDRE    Y +TV A    GV        V + V+D ND+ P F   
Sbjct: 729 SITEDGALYAPKGLDREARQNYSITVIAESQRGV----GVFQVSVIVLDENDHAPEFTSP 784

Query: 585 LYTANIMEDALVGTSVS---QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR- 640
           LY   I E++  GT V+    + ATD D G+N    + L  +  E   F I P +G++  
Sbjct: 785 LYEGRITENSPPGTKVNLSIPITATDKDEGINQNFVFTLHGERSE--LFRIHPTTGLVYF 842

Query: 641 ---TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687
               ++ LDRE+ A +    VA D G     S +   I + D+ND+ PVF
Sbjct: 843 EGIDDRTLDREARANYSFTIVAKDNGGLTSESRL--RITVTDVNDNSPVF 890


>UniRef50_UPI000069FDB0 Cluster: Protocadherin LKC precursor
           (PC-LKC).; n=3; Xenopus tropicalis|Rep: Protocadherin
           LKC precursor (PC-LKC). - Xenopus tropicalis
          Length = 1312

 Score =  198 bits (483), Expect = 2e-48
 Identities = 226/864 (26%), Positives = 372/864 (43%), Gaps = 97/864 (11%)

Query: 13  VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72
           V D ND+ PVF    YEAS+RE    G+ V ++ A D D      V Y+I     D + P
Sbjct: 116 VEDRNDNDPVFLGIPYEASIREDQPLGSIVFSVSAVDFDDDGRVPVTYSI-----DEIIP 170

Query: 73  EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL-- 130
            D             ++F I      +L       EK   Y + + ATD+     +    
Sbjct: 171 NDLQS---------NNLFYILLNGSIILNDTLNYNEKSIFYQMTINATDKGGLFHNHFMY 221

Query: 131 -SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            S+ A + + +ID  D  PQF    Y+VS++E+I++     I ++ A D D G N  I+Y
Sbjct: 222 RSTLAYVSLKVIDLPDLDPQFINAPYSVSIEENIAL--GTTIFRVTAIDGDRGINDEIQY 279

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV----RSYRLVIRAQDG----GSPSRSNTT 241
           +I   +    F I+S SG++ +   +D E +        L + AQ+      +   ++TT
Sbjct: 280 SIQDSSRHGLFDINSKSGEIFVTAKIDREALVQDGEQVLLTVMAQEKNLNVNAEKATSTT 339

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT--MTDK 299
            + + + D+NDN P FY     +      P    +  ++ + +     A+L  T    DK
Sbjct: 340 TVTVRVLDINDNKPNFYNCEIDDCDFSAAPTLSFLGEIEEHSSIRVPVAKLKITGHDPDK 399

Query: 300 DYTGNVDLPI--------TIDP----RSGWVYT----SGQLDRETQAKYQL-LVTATDGG 342
           D  GN +L +        T+ P     +G +      S  +D E   + ++  + A D G
Sbjct: 400 DKNGNFNLYLRGKDQDCFTVSPARVQNTGLIQVLVKDSVAIDYEKVHQMEVEQIVANDTG 459

Query: 343 DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLH 400
                + AT              F    Y +E+ E+ P GT + T+TATD D  E  ++ 
Sbjct: 460 LQDCCSYATVTIDIIDINDHTPEFSQDTYYLEVMENCPDGTQIGTITATDLDSGELGKIT 519

Query: 401 YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT 460
           Y++   + R  F + S +G         LD ++   Y  T+ A D    + TA+++I I 
Sbjct: 520 YQLLPESIRQIFHVDSDSGEITAVNGNLLDRERRSLYYATLQAADGLNATGTALLEITIL 579

Query: 461 DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV--GINAQITYSLSSEISNEAVA 518
           D N+  P    A  + ++F +       + + A D+D     N++I + L   + +    
Sbjct: 580 DENDEIP---TAIGSYNIFVNENTDDVRIQIEAFDADEPNTNNSRIEFELLPSVLS---- 632

Query: 519 HHDQQFVINPQTGAITTNKLLDRETMSG-----YLLTVTARDGGVPSLSDTTDVEISVVD 573
                F +N  TG IT+   LDRE +        +LTV   D GVPSLS   +V I+V D
Sbjct: 633 ---SNFSVNVTTGLITSIGPLDREAIDEKDNGCIVLTVKLYDLGVPSLSSEVNVTINVED 689

Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVI 632
           +NDN PVF + +Y    + ++ +   V  +  +D D   LN R+ + +       G+F+I
Sbjct: 690 LNDNVPVFSKTVYDF-FVNESTIAAQVGILLVSDQDQTELNNRVSFRI--SQGGSGNFII 746

Query: 633 ---DPASGV------IRTNKALDRESVATHDLKAVAIDGGT--PPQSSTVIVHIKIEDIN 681
                 SG+      +  +  LD E+   + L   A D G      ++T    +++ D+N
Sbjct: 747 RNQKVESGLYNGILSLDPDVMLDYETQKNYTLIIEAQDNGLHGVSHTATATASVQVLDLN 806

Query: 682 DSPPVFESDCL-TFYISENSPIG-TTIGEIRAHDPDE----GPNAVVHYSIKGGDDSNSF 735
           D PP  +   L   ++ EN  +G   +  ++AHDPD        A+     K G+D  + 
Sbjct: 807 DEPPYVDPSSLNNLFLLENRTVGLELLTTLKAHDPDTIHELEFQALSLQCFKNGNDIGNI 866

Query: 736 SLETRQGSDKAEL-VTMVD-LDYE-------SPRKKYELVIRAASPPLWNDVRVEILVTD 786
             +    +   EL V   + +DYE         R + +L +          +RV+IL  D
Sbjct: 867 CYDWIWLAPNGELFVNDTEVVDYELCDVMVMMLRVEDKLTLIGDRYSKNESLRVDIL--D 924

Query: 787 VNDNAPVMKDFQIIFNNYKDCFPV 810
           VNDNAP   D   +F    D  P+
Sbjct: 925 VNDNAPEFLDVDEVFVVVPDVAPI 948



 Score =  184 bits (447), Expect = 4e-44
 Identities = 207/760 (27%), Positives = 331/760 (43%), Gaps = 84/760 (11%)

Query: 138 VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI---IGG 194
           V + D NDN P F    Y  S+ ED  +    ++  + A D D      + Y+I   I  
Sbjct: 114 VIVEDRNDNDPVFLGIPYEASIREDQPL--GSIVFSVSAVDFDDDGRVPVTYSIDEIIPN 171

Query: 195 NTQMQ--FSIDSLSGDVSLVKTLDY-EQVRSYRLVIRAQDGGS------PSRSNTTQLLI 245
           + Q    F I  L+G + L  TL+Y E+   Y++ I A D G         RS    + +
Sbjct: 172 DLQSNNLFYI-LLNGSIILNDTLNYNEKSIFYQMTINATDKGGLFHNHFMYRSTLAYVSL 230

Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
            + D+ D  P+F  + +  S+ EN+ +G +I RV A D D G+N E+ Y++ D    G  
Sbjct: 231 KVIDLPDLDPQFINAPYSVSIEENIALGTTIFRVTAIDGDRGINDEIQYSIQDSSRHGLF 290

Query: 306 DLPITIDPRSGWVYTSGQLDRE--TQAKYQLLVT--ATDGGDPPRSATATXXXXXXXXXX 361
           D    I+ +SG ++ + ++DRE   Q   Q+L+T  A +      +  AT          
Sbjct: 291 D----INSKSGEIFVTAKIDREALVQDGEQVLLTVMAQEKNLNVNAEKATSTTTVTVRVL 346

Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVT-------------------LTATDADEDNRLHYE 402
                 P  Y  E+ + +    P ++                   +T  D D+D   ++ 
Sbjct: 347 DINDNKPNFYNCEIDDCDFSAAPTLSFLGEIEEHSSIRVPVAKLKITGHDPDKDKNGNFN 406

Query: 403 I-TGGNTRGRFSITSQ--NGRGLITV----AQPLDF-KQERRYVLTVSATDSGGRS--DT 452
           +   G  +  F+++       GLI V    +  +D+ K  +  V  + A D+G +     
Sbjct: 407 LYLRGKDQDCFTVSPARVQNTGLIQVLVKDSVAIDYEKVHQMEVEQIVANDTGLQDCCSY 466

Query: 453 AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512
           A V I+I D N++ P F    Y   V E+ P GT +  ++ATD D G   +ITY L  E 
Sbjct: 467 ATVTIDIIDINDHTPEFSQDTYYLEVMENCPDGTQIGTITATDLDSGELGKITYQLLPE- 525

Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572
           S   + H D     + +  A+  N LLDRE  S Y  T+ A DG   + + T  +EI+++
Sbjct: 526 SIRQIFHVDSD---SGEITAVNGN-LLDRERRSLYYATLQAADG--LNATGTALLEITIL 579

Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV--GLNGRIHYELDPKDREEGSF 630
           D ND  P     + + NI  +        Q+ A DAD     N RI +EL P      +F
Sbjct: 580 DENDEIPT---AIGSYNIFVNENTDDVRIQIEAFDADEPNTNNSRIEFELLPSVL-SSNF 635

Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAI-----DGGTPPQSSTVIVHIKIEDINDSPP 685
            ++  +G+I +   LDRE++   D   + +     D G P  SS V V I +ED+ND+ P
Sbjct: 636 SVNVTTGLITSIGPLDREAIDEKDNGCIVLTVKLYDLGVPSLSSEVNVTINVEDLNDNVP 695

Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGP-NAVVHYSIKGGDDSNSFSLETRQGSD 744
           VF      F+++E S I   +G +   D D+   N  V + I  G   N      +  S 
Sbjct: 696 VFSKTVYDFFVNE-STIAAQVGILLVSDQDQTELNNRVSFRISQGGSGNFIIRNQKVESG 754

Query: 745 KAELVTMVD----LDYESPRKKYELVIRAASPPLWN-----DVRVEILVTDVNDNAPVMK 795
               +  +D    LDYE+ +K Y L+I A    L            + V D+ND  P + 
Sbjct: 755 LYNGILSLDPDVMLDYET-QKNYTLIIEAQDNGLHGVSHTATATASVQVLDLNDEPPYVD 813

Query: 796 DFQI--IFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILS 833
              +  +F        +     + A+D D   +L+++ LS
Sbjct: 814 PSSLNNLFLLENRTVGLELLTTLKAHDPDTIHELEFQALS 853



 Score =  156 bits (378), Expect = 9e-36
 Identities = 178/652 (27%), Positives = 283/652 (43%), Gaps = 81/652 (12%)

Query: 252 DNAPRFYTSLFQESVSENVP-IGYSIVRVQAYDADEGVNAELTYTMTDKD-YTGNVDLPI 309
           + AP F +++    + E+ P +G  +  + A DAD   N  LTY+M  +D Y  NV+L  
Sbjct: 22  NTAPEFASNMTSAFIPEDTPLVGKCVFWIVARDAD---NDPLTYSMEGQDSYYFNVNL-- 76

Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369
                +G V  +  LD E   +Y + +       P                     F+  
Sbjct: 77  ----MTGEVQLALPLDYEVGFQYLVQLLRNI---PALQVIRQFPVIVEDRNDNDPVFLGI 129

Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITG--GNTRGRFSITSQNGRGLITV 425
            YE  + ED+P G+ V +++A D D+D R+   Y I     N     ++      G I +
Sbjct: 130 PYEASIREDQPLGSIVFSVSAVDFDDDGRVPVTYSIDEIIPNDLQSNNLFYILLNGSIIL 189

Query: 426 AQPLDFKQERR-YVLTVSATDSGG--------RSDTAMVQINITDANNYAPVFENAPYTA 476
              L++ ++   Y +T++ATD GG        RS  A V + + D  +  P F NAPY+ 
Sbjct: 190 NDTLNYNEKSIFYQMTINATDKGGLFHNHFMYRSTLAYVSLKVIDLPDLDPQFINAPYSV 249

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
           S+ E+  +GTT+  V+A D D GIN +I YS+         + H   F IN ++G I   
Sbjct: 250 SIEENIALGTTIFRVTAIDGDRGINDEIQYSIQDS------SRHG-LFDINSKSGEIFVT 302

Query: 537 KLLDRETM----SGYLLTVTARDGGV----PSLSDTTDVEISVVDVNDNEPVF------- 581
             +DRE +       LLTV A++  +       + TT V + V+D+NDN+P F       
Sbjct: 303 AKIDREALVQDGEQVLLTVMAQEKNLNVNAEKATSTTTVTVRVLDINDNKPNFYNCEIDD 362

Query: 582 ------KQQLYTANIMEDALVGTSVSQVGAT--DADVGLNGRIHYELDPKDREEGSFVID 633
                     +   I E + +   V+++  T  D D   NG  +  L  KD++   F + 
Sbjct: 363 CDFSAAPTLSFLGEIEEHSSIRVPVAKLKITGHDPDKDKNGNFNLYLRGKDQD--CFTVS 420

Query: 634 PA----SGVI----RTNKALDRESVATHDL-KAVAIDGGTPPQSSTVIVHIKIEDINDSP 684
           PA    +G+I    + + A+D E V   ++ + VA D G     S   V I I DIND  
Sbjct: 421 PARVQNTGLIQVLVKDSVAIDYEKVHQMEVEQIVANDTGLQDCCSYATVTIDIIDINDHT 480

Query: 685 PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD 744
           P F  D     + EN P GT IG I A D D G    + Y +        F +++  G  
Sbjct: 481 PEFSQDTYYLEVMENCPDGTQIGTITATDLDSGELGKITYQLLPESIRQIFHVDSDSGEI 540

Query: 745 KAELVTMVDLDYESPRKKYELVIRAASP-PLWNDVRVEILVTDVNDNAP-VMKDFQIIFN 802
            A    ++D      R  Y   ++AA          +EI + D ND  P  +  + I  N
Sbjct: 541 TAVNGNLLD---RERRSLYYATLQAADGLNATGTALLEITILDENDEIPTAIGSYNIFVN 597

Query: 803 NYKDCFPVGPFGRVPAYDADV----TDKLQYRILSGNNANLILLNETTGSMT 850
              D   +    ++ A+DAD       ++++ +L    ++   +N TTG +T
Sbjct: 598 ENTDDVRI----QIEAFDADEPNTNNSRIEFELLPSVLSSNFSVNVTTGLIT 645



 Score =  150 bits (364), Expect = 5e-34
 Identities = 186/758 (24%), Positives = 312/758 (41%), Gaps = 72/758 (9%)

Query: 141 IDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQF 200
           +   +  P+F+    +  + ED  +    V   I A DAD   N  + Y++ G ++   F
Sbjct: 18  VSSQNTAPEFASNMTSAFIPEDTPLVGKCVFW-IVARDAD---NDPLTYSMEGQDSYY-F 72

Query: 201 SIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260
           +++ ++G+V L   LDYE    Y + +       P+     Q  + + D NDN P F   
Sbjct: 73  NVNLMTGEVQLALPLDYEVGFQYLVQLLRN---IPALQVIRQFPVIVEDRNDNDPVFLGI 129

Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD---KDYTGNVDLPITIDPRSGW 317
            ++ S+ E+ P+G  +  V A D D+     +TY++ +    D   N    I ++   G 
Sbjct: 130 PYEASIREDQPLGSIVFSVSAVDFDDDGRVPVTYSIDEIIPNDLQSNNLFYILLN---GS 186

Query: 318 VYTSGQLD-RETQAKYQLLVTATDGGD------PPRSATATXXXXXXXXXXXXXXFMPGQ 370
           +  +  L+  E    YQ+ + ATD G         RS  A               F+   
Sbjct: 187 IILNDTLNYNEKSIFYQMTINATDKGGLFHNHFMYRSTLAYVSLKVIDLPDLDPQFINAP 246

Query: 371 YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLIT--VA 426
           Y V + E+   GT +  +TA D D   ++ + Y I   +  G F I S++G   +T  + 
Sbjct: 247 YSVSIEENIALGTTIFRVTAIDGDRGINDEIQYSIQDSSRHGLFDINSKSGEIFVTAKID 306

Query: 427 QPLDFKQERRYVLTVSATDSG------GRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
           +    +   + +LTV A +          + T  V + + D N+  P F N       F 
Sbjct: 307 REALVQDGEQVLLTVMAQEKNLNVNAEKATSTTTVTVRVLDINDNKPNFYNCEIDDCDFS 366

Query: 481 DAPIGTTVLVVSATDS------DVGINAQITYSLSSEISNEAVAHHDQQ-FVINP----Q 529
            AP  + +  +    S       + I         +   N  +   DQ  F ++P     
Sbjct: 367 AAPTLSFLGEIEEHSSIRVPVAKLKITGHDPDKDKNGNFNLYLRGKDQDCFTVSPARVQN 426

Query: 530 TGAITT----NKLLDRETMSGYLLT-VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584
           TG I      +  +D E +    +  + A D G+        V I ++D+ND+ P F Q 
Sbjct: 427 TGLIQVLVKDSVAIDYEKVHQMEVEQIVANDTGLQDCCSYATVTIDIIDINDHTPEFSQD 486

Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR--TN 642
            Y   +ME+   GT +  + ATD D G  G+I Y+L P+   +  F +D  SG I     
Sbjct: 487 TYYLEVMENCPDGTQIGTITATDLDSGELGKITYQLLPESIRQ-IFHVDSDSGEITAVNG 545

Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
             LDRE  + +     A DG     + T ++ I I D ND  P         +++EN+  
Sbjct: 546 NLLDRERRSLYYATLQAADGLN--ATGTALLEITILDENDEIPT-AIGSYNIFVNENTD- 601

Query: 703 GTTIGEIRAHDPDE--GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV-DLDYESP 759
              I +I A D DE    N+ + + +     S++FS+    G     L+T +  LD E+ 
Sbjct: 602 DVRI-QIEAFDADEPNTNNSRIEFELLPSVLSSNFSVNVTTG-----LITSIGPLDREAI 655

Query: 760 RKK----YELVIR---AASPPLWNDVRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPV 810
            +K      L ++      P L ++V V I V D+NDN PV     +    N       V
Sbjct: 656 DEKDNGCIVLTVKLYDLGVPSLSSEVNVTINVEDLNDNVPVFSKTVYDFFVNESTIAAQV 715

Query: 811 GPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGS 848
           G          ++ +++ +RI  G + N I+ N+   S
Sbjct: 716 GILLVSDQDQTELNNRVSFRISQGGSGNFIIRNQKVES 753



 Score =  147 bits (356), Expect = 4e-33
 Identities = 207/839 (24%), Positives = 344/839 (41%), Gaps = 104/839 (12%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + V+D  D  P F    Y  S+ E  + GTT+  + A D D G N E++Y+I+       
Sbjct: 230  LKVIDLPDLDPQFINAPYSVSIEENIALGTTIFRVTAIDGDRGINDEIQYSIQ------- 282

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR----YTVLVKATDQASPV 126
               D+             +F I+ +SG +   A +DRE + +      + V A ++   V
Sbjct: 283  ---DSSR---------HGLFDINSKSGEIFVTAKIDREALVQDGEQVLLTVMAQEKNLNV 330

Query: 127  S-DRLSSTATIHVNIIDDNDNYPQFSE-------------KTYTVSVDEDISVTDNPVIA 172
            + ++ +ST T+ V ++D NDN P F                ++   ++E  S+       
Sbjct: 331  NAEKATSTTTVTVRVLDINDNKPNFYNCEIDDCDFSAAPTLSFLGEIEEHSSIRVPVAKL 390

Query: 173  KIKATDADVGANSAIRYAIIGGNTQMQFSIDSL----SGDVS-LVK---TLDYEQVRSYR 224
            KI   D D   N       + G  Q  F++       +G +  LVK    +DYE+V    
Sbjct: 391  KITGHDPDKDKNGNFNL-YLRGKDQDCFTVSPARVQNTGLIQVLVKDSVAIDYEKVHQME 449

Query: 225  LV-IRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYD 283
            +  I A D G     +   + I+I D+ND+ P F    +   V EN P G  I  + A D
Sbjct: 450  VEQIVANDTGLQDCCSYATVTIDIIDINDHTPEFSQDTYYLEVMENCPDGTQIGTITATD 509

Query: 284  ADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV--YTSGQLDRETQAKYQLLVTATDG 341
             D G   ++TY +  +    ++     +D  SG +       LDRE ++ Y   + A DG
Sbjct: 510  LDSGELGKITYQLLPE----SIRQIFHVDSDSGEITAVNGNLLDRERRSLYYATLQAADG 565

Query: 342  GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN---- 397
             +   +A                    G Y + + E+       + + A DADE N    
Sbjct: 566  LNATGTALLEITILDENDEIPTAI---GSYNIFVNENTDDVR--IQIEAFDADEPNTNNS 620

Query: 398  RLHYEITGGNTRGRFSITSQNGRGLITVAQPL-----DFKQERRYVLTVSATDSG--GRS 450
            R+ +E+        FS+      GLIT   PL     D K     VLTV   D G    S
Sbjct: 621  RIEFELLPSVLSSNFSVNVTT--GLITSIGPLDREAIDEKDNGCIVLTVKLYDLGVPSLS 678

Query: 451  DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLS 509
                V IN+ D N+  PVF    Y   V  ++ I   V ++  +D D   +N ++++ +S
Sbjct: 679  SEVNVTINVEDLNDNVPVFSKTVYDFFV-NESTIAAQVGILLVSDQDQTELNNRVSFRIS 737

Query: 510  SEISNEAVAHHDQQFVINPQTGAITTNK--LLDRETMSGYLLTVTARDGGVPSLSD--TT 565
               S   +   +Q+       G ++ +   +LD ET   Y L + A+D G+  +S   T 
Sbjct: 738  QGGSGNFII-RNQKVESGLYNGILSLDPDVMLDYETQKNYTLIIEAQDNGLHGVSHTATA 796

Query: 566  DVEISVVDVNDNEP-VFKQQLYTANIMEDALVGTS-VSQVGATDADV--GLNGR-IHYEL 620
               + V+D+ND  P V    L    ++E+  VG   ++ + A D D    L  + +  + 
Sbjct: 797  TASVQVLDLNDEPPYVDPSSLNNLFLLENRTVGLELLTTLKAHDPDTIHELEFQALSLQC 856

Query: 621  DPKDREEGSFVID----PASGVIRTN--KALDRESVATHDLKAVAIDGGT---PPQSSTV 671
                 + G+   D      +G +  N  + +D E      +     D  T      S   
Sbjct: 857  FKNGNDIGNICYDWIWLAPNGELFVNDTEVVDYELCDVMVMMLRVEDKLTLIGDRYSKNE 916

Query: 672  IVHIKIEDINDSPPVF-ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD 730
             + + I D+ND+ P F + D +   + + +PI   +  ++A D D G NAV+ +SI    
Sbjct: 917  SLRVDILDVNDNAPEFLDVDEVFVVVPDVAPIDYQVALVKATDKDSGLNAVLKFSIA--- 973

Query: 731  DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTD 786
                 S+E   G     L+ +  +   S ++ Y+  IR AS     L  + RV ++  D
Sbjct: 974  -----SVEFISGDSTRPLLNIFTIVTTSEKEIYQGSIRVASSLDATLKGNYRVTVIAED 1027



 Score =  142 bits (344), Expect = 1e-31
 Identities = 162/606 (26%), Positives = 267/606 (44%), Gaps = 74/606 (12%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I+++D NDH+P F    Y   V E    GT + T+ ATD D G+  ++ Y         L
Sbjct: 471  IDIIDINDHTPEFSQDTYYLEVMENCPDGTQIGTITATDLDSGELGKITYQ--------L 522

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGAL--LTRASLDREKVARYTVLVKATDQASPVSD 128
             PE            ++ +F +D  SG +  +    LDRE+ + Y   ++A D  +    
Sbjct: 523  LPES-----------IRQIFHVDSDSGEITAVNGNLLDRERRSLYYATLQAADGLNA--- 568

Query: 129  RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA--NSA 186
              + TA + + I+D+ND  P  +  +Y + V+E+   TD+ V  +I+A DAD     NS 
Sbjct: 569  --TGTALLEITILDENDEIPT-AIGSYNIFVNEN---TDD-VRIQIEAFDADEPNTNNSR 621

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR-----LVIRAQDGGSPSRSNTT 241
            I + ++       FS++  +G ++ +  LD E +         L ++  D G PS S+  
Sbjct: 622  IEFELLPSVLSSNFSVNVTTGLITSIGPLDREAIDEKDNGCIVLTVKLYDLGVPSLSSEV 681

Query: 242  QLLINIRDVNDNAPRFYTSLFQESVSEN-VPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
             + IN+ D+NDN P F  +++   V+E+ +     I+ V   D  E +N  +++ ++   
Sbjct: 682  NVTINVEDLNDNVPVFSKTVYDFFVNESTIAAQVGILLVSDQDQTE-LNNRVSFRISQGG 740

Query: 301  YTGNVDL---PITIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGG--DPPRSATATXX 353
             +GN  +    +     +G +       LD ETQ  Y L++ A D G      +ATAT  
Sbjct: 741  -SGNFIIRNQKVESGLYNGILSLDPDVMLDYETQKNYTLIIEAQDNGLHGVSHTATATAS 799

Query: 354  XXXXXXXXXXXXFMPGQYE-VELAEDEPPGTPVVT-LTATDADEDNRLHYE------ITG 405
                          P     + L E+   G  ++T L A D D  + L ++         
Sbjct: 800  VQVLDLNDEPPYVDPSSLNNLFLLENRTVGLELLTTLKAHDPDTIHELEFQALSLQCFKN 859

Query: 406  GNTRGRFSIT----SQNGRGLITVAQPLDFKQERRYVLTVSATDS----GGR-SDTAMVQ 456
            GN  G         + NG   +   + +D++     V+ +   D     G R S    ++
Sbjct: 860  GNDIGNICYDWIWLAPNGELFVNDTEVVDYELCDVMVMMLRVEDKLTLIGDRYSKNESLR 919

Query: 457  INITDANNYAPVFENAPYTASVFED-APIGTTVLVVSATDSDVGINAQITYSLSSE--IS 513
            ++I D N+ AP F +      V  D API   V +V ATD D G+NA + +S++S   IS
Sbjct: 920  VDILDVNDNAPEFLDVDEVFVVVPDVAPIDYQVALVKATDKDSGLNAVLKFSIASVEFIS 979

Query: 514  NEAVAHHDQQFVINPQT------GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567
             ++       F I   +      G+I     LD      Y +TV A D G PSL+ T  +
Sbjct: 980  GDSTRPLLNIFTIVTTSEKEIYQGSIRVASSLDATLKGNYRVTVIAEDSGNPSLTATRVL 1039

Query: 568  EISVVD 573
            +I  VD
Sbjct: 1040 DIFAVD 1045



 Score =  134 bits (325), Expect = 3e-29
 Identities = 146/574 (25%), Positives = 259/574 (45%), Gaps = 53/574 (9%)

Query: 375 LAEDEP-PGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ 433
           + ED P  G  V  + A DAD D  L Y + G ++   F++    G   + +A PLD++ 
Sbjct: 36  IPEDTPLVGKCVFWIVARDADNDP-LTYSMEGQDSY-YFNVNLMTGE--VQLALPLDYEV 91

Query: 434 ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
             +Y++ +   +           + + D N+  PVF   PY AS+ ED P+G+ V  VSA
Sbjct: 92  GFQYLVQL-LRNIPALQVIRQFPVIVEDRNDNDPVFLGIPYEASIREDQPLGSIVFSVSA 150

Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD-RETMSGYLLTVT 552
            D D      +TYS+   I N+  +++    ++N   G+I  N  L+  E    Y +T+ 
Sbjct: 151 VDFDDDGRVPVTYSIDEIIPNDLQSNNLFYILLN---GSIILNDTLNYNEKSIFYQMTIN 207

Query: 553 ARD-GGV-----PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
           A D GG+        S    V + V+D+ D +P F    Y+ +I E+  +GT++ +V A 
Sbjct: 208 ATDKGGLFHNHFMYRSTLAYVSLKVIDLPDLDPQFINAPYSVSIEENIALGTTIFRVTAI 267

Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD----LKAVA--- 659
           D D G+N  I Y +    R  G F I+  SG I     +DRE++        L  +A   
Sbjct: 268 DGDRGINDEIQYSIQDSSR-HGLFDINSKSGEIFVTAKIDREALVQDGEQVLLTVMAQEK 326

Query: 660 -IDGGTPPQSSTVIVHIKIEDINDSPPVFES----DC-------LTFY--ISENSPIGTT 705
            ++      +ST  V +++ DIND+ P F +    DC       L+F   I E+S I   
Sbjct: 327 NLNVNAEKATSTTTVTVRVLDINDNKPNFYNCEIDDCDFSAAPTLSFLGEIEEHSSIRVP 386

Query: 706 IGEIR--AHDPDEGPNAVVHYSIKGGD-DSNSFSLETRQGSDKAELVT--MVDLDYESPR 760
           + +++   HDPD+  N   +  ++G D D  + S    Q +   +++    V +DYE   
Sbjct: 387 VAKLKITGHDPDKDKNGNFNLYLRGKDQDCFTVSPARVQNTGLIQVLVKDSVAIDYEKVH 446

Query: 761 K-KYELVIR--AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVP 817
           + + E ++          +   V I + D+ND+ P            ++C      G + 
Sbjct: 447 QMEVEQIVANDTGLQDCCSYATVTIDIIDINDHTPEFSQDTYYLEVMENCPDGTQIGTIT 506

Query: 818 AYDADVTD--KLQYRILSGNNANLILLNETTGSMTL--SPQLNTNVPKLATMEVSVTDGV 873
           A D D  +  K+ Y++L  +   +  ++  +G +T      L+     L    +   DG+
Sbjct: 507 ATDLDSGELGKITYQLLPESIRQIFHVDSDSGEITAVNGNLLDRERRSLYYATLQAADGL 566

Query: 874 NEI-KAMMQLSVRLITEEM--LLNSITVRLNDMT 904
           N    A++++++    +E+   + S  + +N+ T
Sbjct: 567 NATGTALLEITILDENDEIPTAIGSYNIFVNENT 600



 Score = 45.2 bits (102), Expect = 0.026
 Identities = 34/139 (24%), Positives = 69/139 (49%), Gaps = 14/139 (10%)

Query: 10   QINVLDCNDHSPVF-EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI---ELV 65
            ++++LD ND++P F ++ +    V + A     V  +KATD+D G NA ++++I   E +
Sbjct: 919  RVDILDVNDNAPEFLDVDEVFVVVPDVAPIDYQVALVKATDKDSGLNAVLKFSIASVEFI 978

Query: 66   TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125
            + D+  P              +++++     G++   +SLD      Y V V A D  +P
Sbjct: 979  SGDSTRP--LLNIFTIVTTSEKEIYQ-----GSIRVASSLDATLKGNYRVTVIAEDSGNP 1031

Query: 126  VSDRLSSTATIHVNIIDDN 144
                L++T  + +  +D++
Sbjct: 1032 ---SLTATRVLDIFAVDES 1047


>UniRef50_UPI0000F2B47D Cluster: PREDICTED: similar to matrix
           metalloproteinase 13; n=8; Theria|Rep: PREDICTED:
           similar to matrix metalloproteinase 13 - Monodelphis
           domestica
          Length = 860

 Score =  196 bits (479), Expect = 5e-48
 Identities = 177/612 (28%), Positives = 263/612 (42%), Gaps = 29/612 (4%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           FR+  ++G L  +  LDRE++           +   V +    +    V + D NDN P 
Sbjct: 87  FRLHRKTGDLFVKEKLDREELCGKAD--PCVLRFEIVLEEPLQSFRAEVRVFDINDNAPM 144

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG---NTQMQF-SIDSL 205
           F      + + E   +     +    A D DVG N    Y +      +   +F S    
Sbjct: 145 FPNHGPVLKIPESTPLGSRFPLQS--AQDLDVGLNGLQNYTLSANAYFHLHTRFRSHGPK 202

Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265
             ++ L+K LD E+     L + A DGGSP++S T Q+LI + DVNDN P+F   +++  
Sbjct: 203 YAELVLIKPLDREEQPQVCLTLTAVDGGSPAKSGTAQILIVVLDVNDNVPQFSRLVYRAQ 262

Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325
           + EN P G  +  V A D DEG N E+ Y++        +     I+  +G +   G +D
Sbjct: 263 ILENSPNGSLVTSVSATDLDEGTNREIVYSLAQN--PEGILQTFHINFENGEIRLRGPVD 320

Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
            E    Y + V A DGG    SA +                +       + ED P  T V
Sbjct: 321 FEAIENYDIDVQAIDGGG--LSAHSKVLVEVMDVNDNAPDVLITSISNRIPEDSPLNT-V 377

Query: 386 VTLTATDADEDNRLHYEIT---GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442
           V L     D D R+  +IT    G+       T +N   L+T    LD ++   Y LT+ 
Sbjct: 378 VALFGV-RDRDIRVGGKITCFIQGDLPFTIKQTFRNSYSLVT-GGTLDREKVAGYNLTIV 435

Query: 443 ATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
           A DSG    S   ++++ I+D N+  PVF+ A YT +V E+      +  V A D D   
Sbjct: 436 AMDSGTPRLSSETIIEVVISDINDNPPVFKEASYTMTVRENNSPAVFIGKVQAEDLDSEE 495

Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560
           NAQITYSL    S +          IN   G +   + +D E +  +   V A +GG   
Sbjct: 496 NAQITYSLLPPESGDLSVF--SYISINSNNGKLYALRSMDYEAIQAFQFVVKAVNGGPLP 553

Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTAN------IMEDALVGTSVSQVGATDADVGLNG 614
           LS    V + V+DVNDN P+    L  +       +   A VG  V++V A D D G N 
Sbjct: 554 LSSQIIVRVVVLDVNDNLPMILYPLQNSTSPCNDLVPRVAEVGYLVTKVVAVDGDSGQNS 613

Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674
            + YEL  K  + G F +   SG IRT + +         +     D G P  S+T  ++
Sbjct: 614 WLSYEL-LKATDLGLFSVGRQSGEIRTLRLISERDSMKQKMVIAVRDHGQPSLSTTATLN 672

Query: 675 IKIEDINDSPPV 686
           I + D    P V
Sbjct: 673 ILLVDGFSDPYV 684



 Score =  191 bits (466), Expect = 2e-46
 Identities = 160/534 (29%), Positives = 258/534 (48%), Gaps = 41/534 (7%)

Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480
           + + +PLD +++ +  LT++A D G   +S TA + I + D N+  P F    Y A + E
Sbjct: 206 LVLIKPLDREEQPQVCLTLTAVDGGSPAKSGTAQILIVVLDVNDNVPQFSRLVYRAQILE 265

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           ++P G+ V  VSATD D G N +I YSL+   + E +    Q F IN + G I     +D
Sbjct: 266 NSPNGSLVTSVSATDLDEGTNREIVYSLAQ--NPEGIL---QTFHINFENGEIRLRGPVD 320

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
            E +  Y + V A DGG   LS  + V + V+DVNDN P       +  I ED+ + T V
Sbjct: 321 FEAIENYDIDVQAIDGG--GLSAHSKVLVEVMDVNDNAPDVLITSISNRIPEDSPLNTVV 378

Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA---SGVIRTNKALDRESVATHDLKA 657
           +  G  D D+ + G+I   +    + +  F I      S  + T   LDRE VA ++L  
Sbjct: 379 ALFGVRDRDIRVGGKITCFI----QGDLPFTIKQTFRNSYSLVTGGTLDREKVAGYNLTI 434

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
           VA+D GTP  SS  I+ + I DIND+PPVF+    T  + EN+     IG+++A D D  
Sbjct: 435 VAMDSGTPRLSSETIIEVVISDINDNPPVFKEASYTMTVRENNSPAVFIGKVQAEDLDSE 494

Query: 718 PNAVVHYSI--KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP--- 772
            NA + YS+      D + FS      S+  +L  +  +DYE+  + ++ V++A +    
Sbjct: 495 ENAQITYSLLPPESGDLSVFSY-ISINSNNGKLYALRSMDYEA-IQAFQFVVKAVNGGPL 552

Query: 773 PLWNDVRVEILVTDVNDNAP-VMKDFQIIFNNYKDCFP-VGPFG----RVPAYDADVTDK 826
           PL + + V ++V DVNDN P ++   Q   +   D  P V   G    +V A D D    
Sbjct: 553 PLSSQIIVRVVVLDVNDNLPMILYPLQNSTSPCNDLVPRVAEVGYLVTKVVAVDGDSGQN 612

Query: 827 --LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLS 883
             L Y +L   +  L  +   +G +     ++        M ++V D G   +     L+
Sbjct: 613 SWLSYELLKATDLGLFSVGRQSGEIRTLRLISERDSMKQKMVIAVRDHGQPSLSTTATLN 672

Query: 884 VRLITEEMLLNSITVRLNDMT-AEQFLSPLLGFFIDGLAAIIPCPKENIYIFSV 936
           + L+      +   V+L D +  E+  +P   + +  LA +      ++++FSV
Sbjct: 673 ILLVDG---FSDPYVQLRDHSKRERKTNPSTKYLVISLAVL-----SSLFLFSV 718



 Score =  141 bits (341), Expect = 3e-31
 Identities = 128/462 (27%), Positives = 205/462 (44%), Gaps = 43/462 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I VLD ND+ P F    Y A + E + +G+ V ++ ATD D G N E+ Y++        
Sbjct: 242 IVVLDVNDNVPQFSRLVYRAQILENSPNGSLVTSVSATDLDEGTNREIVYSL------AQ 295

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           NPE            +   F I+  +G +  R  +D E +  Y + V+A D        L
Sbjct: 296 NPE-----------GILQTFHINFENGEIRLRGPVDFEAIENYDIDVQAIDGGG-----L 339

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           S+ + + V ++D NDN P     + +  + ED  +  N V+A     D D+     I   
Sbjct: 340 SAHSKVLVEVMDVNDNAPDVLITSISNRIPEDSPL--NTVVALFGVRDRDIRVGGKITCF 397

Query: 191 IIGGNTQMQFSI-DSLSGDVSLVK--TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
           I G    + F+I  +     SLV   TLD E+V  Y L I A D G+P  S+ T + + I
Sbjct: 398 IQG---DLPFTIKQTFRNSYSLVTGGTLDREKVAGYNLTIVAMDSGTPRLSSETIIEVVI 454

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            D+NDN P F  + +  +V EN      I +VQA D D   NA++TY++   + +G++ +
Sbjct: 455 SDINDNPPVFKEASYTMTVRENNSPAVFIGKVQAEDLDSEENAQITYSLLPPE-SGDLSV 513

Query: 308 --PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
              I+I+  +G +Y    +D E    +Q +V A +GG  P S+                 
Sbjct: 514 FSYISINSNNGKLYALRSMDYEAIQAFQFVVKAVNGGPLPLSSQIIVRVVVLDVNDNLPM 573

Query: 366 FM-PGQYEVELAEDEPP-----GTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQ 417
            + P Q       D  P     G  V  + A D D  +++ L YE+      G FS+  Q
Sbjct: 574 ILYPLQNSTSPCNDLVPRVAEVGYLVTKVVAVDGDSGQNSWLSYELLKATDLGLFSVGRQ 633

Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINI 459
           +G   I   + +  +   +  + ++  D G  S +    +NI
Sbjct: 634 SGE--IRTLRLISERDSMKQKMVIAVRDHGQPSLSTTATLNI 673



 Score = 99.5 bits (237), Expect = 1e-18
 Identities = 82/278 (29%), Positives = 124/278 (44%), Gaps = 12/278 (4%)

Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVNDNEPV 580
           Q F ++ +TG +   + LDRE + G       R +  +     +   E+ V D+NDN P+
Sbjct: 85  QHFRLHRKTGDLFVKEKLDREELCGKADPCVLRFEIVLEEPLQSFRAEVRVFDINDNAPM 144

Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK---DREEGSFVIDPASG 637
           F        I E   +G+      A D DVGLNG  +Y L                P   
Sbjct: 145 FPNHGPVLKIPESTPLGSRFPLQSAQDLDVGLNGLQNYTLSANAYFHLHTRFRSHGPKYA 204

Query: 638 VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697
            +   K LDRE      L   A+DGG+P +S T  + I + D+ND+ P F        I 
Sbjct: 205 ELVLIKPLDREEQPQVCLTLTAVDGGSPAKSGTAQILIVVLDVNDNVPQFSRLVYRAQIL 264

Query: 698 ENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS--NSFSLETRQGSDKAELVTMVDLD 755
           ENSP G+ +  + A D DEG N  + YS+    +    +F +    G    E+     +D
Sbjct: 265 ENSPNGSLVTSVSATDLDEGTNREIVYSLAQNPEGILQTFHINFENG----EIRLRGPVD 320

Query: 756 YESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAP 792
           +E+  + Y++ ++A     L    +V + V DVNDNAP
Sbjct: 321 FEA-IENYDIDVQAIDGGGLSAHSKVLVEVMDVNDNAP 357



 Score = 82.2 bits (194), Expect = 2e-13
 Identities = 66/244 (27%), Positives = 110/244 (45%), Gaps = 21/244 (8%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ + D ND+ PVF+   Y  +VRE  S    +  ++A D D  +NA++ Y++       
Sbjct: 451 EVVISDINDNPPVFKEASYTMTVRENNSPAVFIGKVQAEDLDSEENAQITYSL------- 503

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
           L PE            V     I+  +G L    S+D E +  +  +VKA +   P+   
Sbjct: 504 LPPESG-------DLSVFSYISINSNNGKLYALRSMDYEAIQAFQFVVKAVN-GGPLP-- 553

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTY-TVSVDEDI--SVTD-NPVIAKIKATDADVGANS 185
           LSS   + V ++D NDN P        + S   D+   V +   ++ K+ A D D G NS
Sbjct: 554 LSSQIIVRVVVLDVNDNLPMILYPLQNSTSPCNDLVPRVAEVGYLVTKVVAVDGDSGQNS 613

Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
            + Y ++       FS+   SG++  ++ +        ++VI  +D G PS S T  L I
Sbjct: 614 WLSYELLKATDLGLFSVGRQSGEIRTLRLISERDSMKQKMVIAVRDHGQPSLSTTATLNI 673

Query: 246 NIRD 249
            + D
Sbjct: 674 LLVD 677


>UniRef50_Q9UJ99 Cluster: Cadherin-22 precursor; n=19;
           Euteleostomi|Rep: Cadherin-22 precursor - Homo sapiens
           (Human)
          Length = 828

 Score =  196 bits (477), Expect = 1e-47
 Identities = 166/575 (28%), Positives = 269/575 (46%), Gaps = 44/575 (7%)

Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYE 218
           V E+ + T+   + KI + D+D G + AI+Y I G      F ID L+GD+  ++ LD E
Sbjct: 71  VVEEYTGTEPLYVGKIHS-DSDEG-DGAIKYTISGEGAGTIFLIDELTGDIHAMERLDRE 128

Query: 219 QVRSYRLVIRAQDGGSPS-RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277
           Q   Y L  +A+D  +       ++ +I ++D+ND+ PRF    +  SV+E  P G S++
Sbjct: 129 QKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHGPYIGSVAELSPTGTSVM 188

Query: 278 RVQAYDADE---GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS-GQLDRETQAKYQ 333
           +V A DAD+   G +A L Y++ D ++        T+DP++G + T+   LDRE+Q +Y+
Sbjct: 189 QVMASDADDPTYGSSARLVYSVLDGEH------HFTVDPKTGVIRTAVPDLDRESQERYE 242

Query: 334 LLVTATD--GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTAT 391
           +++ ATD  G     S + T              F    Y+  + E  P GT V  + A 
Sbjct: 243 VVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQESAPIGTAVGRVKAE 302

Query: 392 DAD--EDNRLHYEITGGNTRGR--FSIT--SQNGRGLITVAQPLDFKQERRYVLTVSA-- 443
           D+D  E+  + Y +   ++ G   F +T  S     +I V + LDF+ +  + + + A  
Sbjct: 303 DSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIVVQKRLDFESQPVHTVILEALN 362

Query: 444 -------TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496
                   D G   D A+V++ +TD +   P F        V EDA +G+ V VV+A D 
Sbjct: 363 KFVDPRFADLGTFRDQAIVRVAVTDVDE-PPEFRPPSGLLEVQEDAQVGSLVGVVTARDP 421

Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556
           D   N  + Y++  E      +  DQ F I+  TGAI T K LDRET   + +TV A + 
Sbjct: 422 DAA-NRPVRYAIDRE------SDLDQIFDIDADTGAIVTGKGLDRETAGWHNITVLAMEA 474

Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG-R 615
              +      + I ++DVNDN P      Y A + EDA  G  +  +   D D    G R
Sbjct: 475 DNHAQLSRASLRIRILDVNDNPPELATP-YEAAVCEDAKPGQLIQTISVVDRDEPQGGHR 533

Query: 616 IHYELDPKDREEGSF----VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671
            ++ L P+      F    + D  + V   +   +R+      L  + +D G P  SST 
Sbjct: 534 FYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVFFLPILVVDSGPPTLSSTG 593

Query: 672 IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706
            + I+I   + S  +   +   F ++ +   G  I
Sbjct: 594 TLTIRICGCDSSGTIQSCNTTAFVMAASLSPGALI 628



 Score =  161 bits (390), Expect = 3e-37
 Identities = 143/503 (28%), Positives = 236/503 (46%), Gaps = 32/503 (6%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           +F ID  +G +     LDRE+   YT+  +A D+A+  +  L   +   + + D ND+ P
Sbjct: 109 IFLIDELTGDIHAMERLDREQKTFYTLRAQARDRAT--NRLLEPESEFIIKVQDINDSEP 166

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDAD---VGANSAIRYAIIGGNTQMQFSIDSL 205
           +F    Y  SV E +S T   V+ ++ A+DAD    G+++ + Y+++ G  +  F++D  
Sbjct: 167 RFLHGPYIGSVAE-LSPTGTSVM-QVMASDADDPTYGSSARLVYSVLDG--EHHFTVDPK 222

Query: 206 SGDV-SLVKTLDYEQVRSYRLVIRAQD--GGSPSRSNTTQLLINIRDVNDNAPRFYTSLF 262
           +G + + V  LD E    Y +VI+A D  G     S +T + I + DVNDN PRF   ++
Sbjct: 223 TGVIRTAVPDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMY 282

Query: 263 QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI--DPRSGWVYT 320
           Q S+ E+ PIG ++ RV+A D+D G N ++TY + D+  +G     +T   D +   +  
Sbjct: 283 QFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIVV 342

Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX------XFMPGQYEVE 374
             +LD E+Q  + +++ A +    PR A                       F P    +E
Sbjct: 343 QKRLDFESQPVHTVILEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLE 402

Query: 375 LAEDEPPGTPVVTLTATDADEDNR-LHYEITGGNTRGR-FSITSQNGRGLITVAQPLDFK 432
           + ED   G+ V  +TA D D  NR + Y I   +   + F I +    G I   + LD +
Sbjct: 403 VQEDAQVGSLVGVVTARDPDAANRPVRYAIDRESDLDQIFDIDADT--GAIVTGKGLDRE 460

Query: 433 QERRYVLTVSA--TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
               + +TV A   D+  +   A ++I I D N+  P     PY A+V EDA  G  +  
Sbjct: 461 TAGWHNITVLAMEADNHAQLSRASLRIRILDVNDNPPELA-TPYEAAVCEDAKPGQLIQT 519

Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAH-HDQQFVINPQTGAITTNKL-LDRETMSGYL 548
           +S  D D     Q  +     +  EA ++ H     I   T A+ T  +  +R+    + 
Sbjct: 520 ISVVDRD---EPQGGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVFF 576

Query: 549 LTVTARDGGVPSLSDTTDVEISV 571
           L +   D G P+LS T  + I +
Sbjct: 577 LPILVVDSGPPTLSSTGTLTIRI 599



 Score =  154 bits (374), Expect = 3e-35
 Identities = 134/427 (31%), Positives = 202/427 (47%), Gaps = 42/427 (9%)

Query: 391 TDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR 449
           +D+DE D  + Y I+G      F I    G   I   + LD +Q+  Y L   A D    
Sbjct: 88  SDSDEGDGAIKYTISGEGAGTIFLIDELTGD--IHAMERLDREQKTFYTLRAQARDRATN 145

Query: 450 ---SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD---VGINAQ 503
                 +   I + D N+  P F + PY  SV E +P GT+V+ V A+D+D    G +A+
Sbjct: 146 RLLEPESEFIIKVQDINDSEPRFLHGPYIGSVAELSPTGTSVMQVMASDADDPTYGSSAR 205

Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL-LDRETMSGYLLTVTARD--GGVPS 560
           + YS+   +  E   HH   F ++P+TG I T    LDRE+   Y + + A D  G +  
Sbjct: 206 LVYSV---LDGE---HH---FTVDPKTGVIRTAVPDLDRESQERYEVVIQATDMAGQLGG 256

Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620
           LS +T V I V DVNDN P F Q++Y  +I E A +GT+V +V A D+DVG N  + Y L
Sbjct: 257 LSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHL 316

Query: 621 DPKDREEGS-FVI----DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV---- 671
             +    G  F +    D    +I   K LD ES   H +   A++    P+ + +    
Sbjct: 317 KDESSSGGDVFKVTTDSDTQEAIIVVQKRLDFESQPVHTVILEALNKFVDPRFADLGTFR 376

Query: 672 ---IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-K 727
              IV + + D+ D PP F        + E++ +G+ +G + A DPD   N  V Y+I +
Sbjct: 377 DQAIVRVAVTDV-DEPPEFRPPSGLLEVQEDAQVGSLVGVVTARDPD-AANRPVRYAIDR 434

Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESP--RKKYELVIRAASPPLWNDVRVEILVT 785
             D    F ++    +D   +VT   LD E+        L + A +    +   + I + 
Sbjct: 435 ESDLDQIFDID----ADTGAIVTGKGLDRETAGWHNITVLAMEADNHAQLSRASLRIRIL 490

Query: 786 DVNDNAP 792
           DVNDN P
Sbjct: 491 DVNDNPP 497



 Score = 99.1 bits (236), Expect = 2e-18
 Identities = 92/349 (26%), Positives = 150/349 (42%), Gaps = 27/349 (7%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V D ND+ P F  + Y+ S++E A  GT V  +KA D D+G+N ++ Y +        
Sbjct: 265 IVVTDVNDNPPRFPQKMYQFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHL-------- 316

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
             +D             D    D +   ++ +  LD E    +TV+++A ++   V  R 
Sbjct: 317 --KDESSSGGDVFKVTTD---SDTQEAIIVVQKRLDFESQPVHTVILEALNKF--VDPRF 369

Query: 131 SSTATIH----VNI-IDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
           +   T      V + + D D  P+F   +  + V ED  V    ++  + A D D  AN 
Sbjct: 370 ADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLEVQEDAQV--GSLVGVVTARDPD-AANR 426

Query: 186 AIRYAIIGGNTQMQ-FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
            +RYAI   +   Q F ID+ +G +   K LD E    + + + A +  + ++ +   L 
Sbjct: 427 PVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRETAGWHNITVLAMEADNHAQLSRASLR 486

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           I I DVNDN P   T  ++ +V E+   G  I  +   D DE       Y     +   N
Sbjct: 487 IRILDVNDNPPELATP-YEAAVCEDAKPGQLIQTISVVDRDEPQGGHRFYFRLVPEAPSN 545

Query: 305 VDLP-ITIDPRSGWVYTSG-QLDRETQAKYQLLVTATDGGDPPRSATAT 351
                + I   +  V+T     +R+ Q  + L +   D G P  S+T T
Sbjct: 546 PHFSLLDIQDNTAAVHTQHVGFNRQEQDVFFLPILVVDSGPPTLSSTGT 594



 Score = 46.8 bits (106), Expect = 0.009
 Identities = 49/204 (24%), Positives = 86/204 (42%), Gaps = 13/204 (6%)

Query: 51  DIGKNAEVEYTIELVTA-DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREK 109
           ++ ++A+V   + +VTA D                 +  +F ID  +GA++T   LDRE 
Sbjct: 402 EVQEDAQVGSLVGVVTARDPDAANRPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRET 461

Query: 110 VARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP 169
              + + V A +  +       S A++ + I+D NDN P+ +   Y  +V ED       
Sbjct: 462 AGWHNITVLAMEADNHAQ---LSRASLRIRILDVNDNPPELA-TPYEAAVCED--AKPGQ 515

Query: 170 VIAKIKATDAD--VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT----LDYEQVRSY 223
           +I  I   D D   G +      +    +   FS+  +  + + V T     + ++   +
Sbjct: 516 LIQTISVVDRDEPQGGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVF 575

Query: 224 RLVIRAQDGGSPSRSNTTQLLINI 247
            L I   D G P+ S+T  L I I
Sbjct: 576 FLPILVVDSGPPTLSSTGTLTIRI 599


>UniRef50_Q66S83 Cluster: Protocadherin 10-like protein; n=1;
           Oikopleura dioica|Rep: Protocadherin 10-like protein -
           Oikopleura dioica (Tunicate)
          Length = 900

 Score =  195 bits (475), Expect = 2e-47
 Identities = 153/529 (28%), Positives = 250/529 (47%), Gaps = 33/529 (6%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLI 423
           F    + + L E    GT +    ATD D  +     Y +        F I   +G   I
Sbjct: 210 FSESTFHLSLPESAEIGTILRLSPATDDDTFQYQVKKYFLESEQKPIFFKIAENSGNFQI 269

Query: 424 T---VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
               + + LD  +  R+VL + A D GGR   A + I I D N+++P+FE++     V E
Sbjct: 270 PQVELIRELDVNKRARHVLKIIAEDGGGRRGEAELIIEIEDINDHSPIFESSQIKVDVSE 329

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           +A I + +  + A+D+D GIN ++ YS    ++  +V    ++F +N  TG +T  K LD
Sbjct: 330 NASIASQITTLYASDADKGINGEVVYSFQENVNPISVT---EKFNLNRSTGELTIAKSLD 386

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK-QQLYTA--NIMEDALVG 597
            E+   ++L V A D GV S    T V I+++D NDN P  +   L +A   I EDA +G
Sbjct: 387 FESAEKFVLHVKAEDKGVGSSPAYTTVVINLIDENDNSPQIRISWLGSAPEKIAEDADLG 446

Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG---VIRTNKALDRESVATHD 654
             ++ V   D D   N  IH E+    +    F ++  S    +++T   LDRE +  ++
Sbjct: 447 AYIALVNVQDDD---NDEIHLEI----QNSSDFELENNSRNRYILKTKSYLDRERIKNYN 499

Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
           LK +A D G P + +   + I +ED+ND+ P F       +I EN+  G  I +I A D 
Sbjct: 500 LKLIARDSGFPVRETIENLKIIVEDVNDNAPFFRHGQYNVHIDENNEPGAVILQILAEDQ 559

Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--- 771
           DEG NA + Y++   D S  F +++  G+  A  +  +D +  +    +   I  AS   
Sbjct: 560 DEGQNAELSYAL--DDSSGLFEIDSENGNIIA--LESIDAEKHTNGTDFVSFIIIASDHG 615

Query: 772 -PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYR 830
            P L     V++ + D+N+  P        F+  K+       G++ A D D T K+ + 
Sbjct: 616 QPSLSGFTEVKVFINDLNEFQPSFMSRNYNFSIEKNSKIGASVGQLEANDMDKTAKMHFS 675

Query: 831 ILSGNNANLILLNETTGSMTLSPQL--NTNVPKLATMEVSVTDGVNEIK 877
           +   N      +N+ TG ++LS  L   +++P      V+VTD    +K
Sbjct: 676 LERENLP--FSINDRTGEISLSRSLLNFSDIPVFYQFRVAVTDSEKRLK 722



 Score =  194 bits (474), Expect = 2e-47
 Identities = 157/575 (27%), Positives = 265/575 (46%), Gaps = 41/575 (7%)

Query: 88  DVFRIDGRSGALLTRASLDREKVA--RYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145
           +   ID  SG L T+  +DREK+   +    ++    ASP   +  +   I + I+D ND
Sbjct: 148 EYLEIDAHSGDLTTKKEIDREKICGIKKECALEIEVLASP--QQFFNVFNIRLLILDLND 205

Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205
           N P+FSE T+ +S+ E   +    ++    ATD D       +Y +      + F I   
Sbjct: 206 NSPKFSESTFHLSLPESAEI--GTILRLSPATDDDTFQYQVKKYFLESEQKPIFFKIAEN 263

Query: 206 SGD-----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260
           SG+     V L++ LD  +   + L I A+DGG   R    +L+I I D+ND++P F +S
Sbjct: 264 SGNFQIPQVELIRELDVNKRARHVLKIIAEDGGG--RRGEAELIIEIEDINDHSPIFESS 321

Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT 320
             +  VSEN  I   I  + A DAD+G+N E+ Y+  +     +V     ++  +G +  
Sbjct: 322 QIKVDVSENASIASQITTLYASDADKGINGEVVYSFQENVNPISVTEKFNLNRSTGELTI 381

Query: 321 SGQLDRETQAKYQLLVTATD---GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377
           +  LD E+  K+ L V A D   G  P  +                     G    ++AE
Sbjct: 382 AKSLDFESAEKFVLHVKAEDKGVGSSPAYTTVVINLIDENDNSPQIRISWLGSAPEKIAE 441

Query: 378 DEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSI-TSQNGRGLITVAQPLDFKQERR 436
           D   G  +  +   D D+++ +H EI   +    F +  +   R ++     LD ++ + 
Sbjct: 442 DADLGAYIALVNVQD-DDNDEIHLEIQNSSD---FELENNSRNRYILKTKSYLDRERIKN 497

Query: 437 YVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494
           Y L + A DSG   R     ++I + D N+ AP F +  Y   + E+   G  +L + A 
Sbjct: 498 YNLKLIARDSGFPVRETIENLKIIVEDVNDNAPFFRHGQYNVHIDENNEPGAVILQILAE 557

Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG----YLLT 550
           D D G NA+++Y+L               F I+ + G I   + +D E  +         
Sbjct: 558 DQDEGQNAELSYALDDS---------SGLFEIDSENGNIIALESIDAEKHTNGTDFVSFI 608

Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610
           + A D G PSLS  T+V++ + D+N+ +P F  + Y  +I +++ +G SV Q+ A D D 
Sbjct: 609 IIASDHGQPSLSGFTEVKVFINDLNEFQPSFMSRNYNFSIEKNSKIGASVGQLEANDMD- 667

Query: 611 GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645
               ++H+ L   +RE   F I+  +G I  +++L
Sbjct: 668 -KTAKMHFSL---ERENLPFSINDRTGEISLSRSL 698



 Score =  179 bits (435), Expect = 1e-42
 Identities = 159/577 (27%), Positives = 259/577 (44%), Gaps = 48/577 (8%)

Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR--LVIRAQDGGSPSR-SNTTQLLI 245
           + II G       ID+ SGD++  K +D E++   +    +  +   SP +  N   + +
Sbjct: 139 FKIIEGQNHEYLEIDAHSGDLTTKKEIDREKICGIKKECALEIEVLASPQQFFNVFNIRL 198

Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
            I D+NDN+P+F  S F  S+ E+  IG +I+R+     D+    ++     + +     
Sbjct: 199 LILDLNDNSPKFSESTFHLSLPESAEIG-TILRLSPATDDDTFQYQVKKYFLESE---QK 254

Query: 306 DLPITIDPRSG-----WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
            +   I   SG      V    +LD   +A++ L + A DGG   R   A          
Sbjct: 255 PIFFKIAENSGNFQIPQVELIRELDVNKRARHVLKIIAEDGGG--RRGEAELIIEIEDIN 312

Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ--- 417
                F   Q +V+++E+    + + TL A+DAD+        +        S+T +   
Sbjct: 313 DHSPIFESSQIKVDVSENASIASQITTLYASDADKGINGEVVYSFQENVNPISVTEKFNL 372

Query: 418 -NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFE---- 470
               G +T+A+ LDF+   ++VL V A D G  S  A   V IN+ D N+ +P       
Sbjct: 373 NRSTGELTIAKSLDFESAEKFVLHVKAEDKGVGSSPAYTTVVINLIDENDNSPQIRISWL 432

Query: 471 -NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
            +AP    + EDA +G  + +V+  D D   N +I   + +    E   +   ++++   
Sbjct: 433 GSAP--EKIAEDADLGAYIALVNVQDDD---NDEIHLEIQNSSDFELENNSRNRYILK-- 485

Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589
                T   LDRE +  Y L + ARD G P      +++I V DVNDN P F+   Y  +
Sbjct: 486 -----TKSYLDRERIKNYNLKLIARDSGFPVRETIENLKIIVEDVNDNAPFFRHGQYNVH 540

Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES 649
           I E+   G  + Q+ A D D G N  + Y LD      G F ID  +G I   +++D E 
Sbjct: 541 IDENNEPGAVILQILAEDQDEGQNAELSYALDD---SSGLFEIDSENGNIIALESIDAEK 597

Query: 650 VATH----DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
                       +A D G P  S    V + I D+N+  P F S    F I +NS IG +
Sbjct: 598 HTNGTDFVSFIIIASDHGQPSLSGFTEVKVFINDLNEFQPSFMSRNYNFSIEKNSKIGAS 657

Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
           +G++ A+D D+   A +H+S++   ++  FS+  R G
Sbjct: 658 VGQLEANDMDK--TAKMHFSLE--RENLPFSINDRTG 690



 Score =  158 bits (383), Expect = 2e-36
 Identities = 139/496 (28%), Positives = 222/496 (44%), Gaps = 45/496 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I + D NDHSP+FE  Q +  V E AS  + + TL A+D D G N EV Y+ +    + +
Sbjct: 306 IEIEDINDHSPIFESSQIKVDVSENASIASQITTLYASDADKGINGEVVYSFQ----ENV 361

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           NP             V + F ++  +G L    SLD E   ++ + VKA D+    S   
Sbjct: 362 NP-----------ISVTEKFNLNRSTGELTIAKSLDFESAEKFVLHVKAEDKGVGSSPAY 410

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           +   T+ +N+ID+NDN PQ    ++  S  E I+  D  + A I   +     N  I   
Sbjct: 411 T---TVVINLIDENDNSPQI-RISWLGSAPEKIA-EDADLGAYIALVNVQDDDNDEIHLE 465

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
           I        F +++ S +  ++KT   LD E++++Y L + A+D G P R     L I +
Sbjct: 466 I---QNSSDFELENNSRNRYILKTKSYLDRERIKNYNLKLIARDSGFPVRETIENLKIIV 522

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            DVNDNAP F    +   + EN   G  I+++ A D DEG NAEL+Y + D   +G  + 
Sbjct: 523 EDVNDNAPFFRHGQYNVHIDENNEPGAVILQILAEDQDEGQNAELSYALDDS--SGLFE- 579

Query: 308 PITIDPRSGWVYTSGQLDRETQAK----YQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
              ID  +G +     +D E           ++ A+D G P  S                
Sbjct: 580 ---IDSENGNIIALESIDAEKHTNGTDFVSFIIIASDHGQPSLSGFTEVKVFINDLNEFQ 636

Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423
             FM   Y   + ++   G  V  L A D D+  ++H+ +   N    FSI  + G   I
Sbjct: 637 PSFMSRNYNFSIEKNSKIGASVGQLEANDMDKTAKMHFSLERENL--PFSINDRTGE--I 692

Query: 424 TVAQP-LDFKQ-ERRYVLTVSATDSGGR---SDTAMVQINITDANNYAPVFENAPYTASV 478
           ++++  L+F      Y   V+ TDS  R    D A V + ++++       ++A   A V
Sbjct: 693 SLSRSLLNFSDIPVFYQFRVAVTDSEKRLKTKDLAEVVVYVSESFRSLENIDDASKAAVV 752

Query: 479 FEDAPIGTTVLVVSAT 494
                 G  +++++ T
Sbjct: 753 LVGIFAGAVIILITIT 768



 Score = 66.1 bits (154), Expect = 1e-08
 Identities = 56/210 (26%), Positives = 98/210 (46%), Gaps = 34/210 (16%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +I V D ND++P F   QY   + E    G  +L + A DQD G+NAE+ Y ++    D+
Sbjct: 519 KIIVEDVNDNAPFFRHGQYNVHIDENNEPGAVILQILAEDQDEGQNAELSYALD----DS 574

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYT----VLVKATDQASP 125
                              +F ID  +G ++   S+D EK    T     ++ A+D   P
Sbjct: 575 -----------------SGLFEIDSENGNIIALESIDAEKHTNGTDFVSFIIIASDHGQP 617

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
               LS    + V I D N+  P F  + Y  S++++  +     + +++A D D  A  
Sbjct: 618 ---SLSGFTEVKVFINDLNEFQPSFMSRNYNFSIEKNSKI--GASVGQLEANDMDKTAK- 671

Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTL 215
            + +++   N  + FSI+  +G++SL ++L
Sbjct: 672 -MHFSLEREN--LPFSINDRTGEISLSRSL 698



 Score = 63.7 bits (148), Expect = 7e-08
 Identities = 65/281 (23%), Positives = 118/281 (41%), Gaps = 13/281 (4%)

Query: 632 IDPASGVIRTNKALDRESVATHDLK-AVAIDGGTPPQSSTVIVHIK--IEDINDSPPVFE 688
           ID  SG + T K +DRE +     + A+ I+    PQ    + +I+  I D+ND+ P F 
Sbjct: 152 IDAHSGDLTTKKEIDREKICGIKKECALEIEVLASPQQFFNVFNIRLLILDLNDNSPKFS 211

Query: 689 SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAEL 748
                  + E++ IGT +    A D D     V  Y ++       F +    G+ +   
Sbjct: 212 ESTFHLSLPESAEIGTILRLSPATDDDTFQYQVKKYFLESEQKPIFFKIAENSGNFQIPQ 271

Query: 749 VTMV-DLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC 807
           V ++ +LD     +    +I         +  + I + D+ND++P+ +  QI  +  ++ 
Sbjct: 272 VELIRELDVNKRARHVLKIIAEDGGGRRGEAELIIEIEDINDHSPIFESSQIKVDVSENA 331

Query: 808 FPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLIL----LNETTGSMTLSPQLNTNVPK 861
                   + A DAD  +  ++ Y      N   +     LN +TG +T++  L+    +
Sbjct: 332 SIASQITTLYASDADKGINGEVVYSFQENVNPISVTEKFNLNRSTGELTIAKSLDFESAE 391

Query: 862 LATMEVSVTD-GVNEIKAMMQLSVRLITEEMLLNSITVRLN 901
              + V   D GV    A   + + LI E    NS  +R++
Sbjct: 392 KFVLHVKAEDKGVGSSPAYTTVVINLIDEND--NSPQIRIS 430


>UniRef50_UPI000069ECF7 Cluster: UPI000069ECF7 related cluster; n=1;
           Xenopus tropicalis|Rep: UPI000069ECF7 UniRef100 entry -
           Xenopus tropicalis
          Length = 714

 Score =  194 bits (473), Expect = 3e-47
 Identities = 161/510 (31%), Positives = 247/510 (48%), Gaps = 43/510 (8%)

Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239
           D GA+ +++Y++ G      F+ID   G+V + K LD E+   +R V+ A D      + 
Sbjct: 1   DNGAHGSLKYSLHGKGANNIFTIDEERGNVFVQKALDREEHGLWRFVVLATDEEGEGLTG 60

Query: 240 TTQLLINIRDVNDNAPRFYTSL--FQESVSENVPIGYSIVRVQAYDAD---EGVNAELTY 294
              ++I + D+NDNAP+F  +L     +V ENVP   +++ + A DAD   E +NA LTY
Sbjct: 61  FADVIIYVVDINDNAPQFTCALSSCNANVYENVPPNTTVLEMTAVDADDKNEEINAILTY 120

Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354
           +M +   T N+    +I+  +G +YT G LDRE   KY LLV   DGG    + TAT   
Sbjct: 121 SMLNN--TMNL---FSINANTGTIYTLGNLDREKNDKYVLLVKVIDGGGLATTGTAT--I 173

Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRF 412
                      F    +   + E     T V+ ++A+D D  E+  L + I  G+   +F
Sbjct: 174 SVLDINDHVPRFTQDSWNSVILETNDINTKVLEVSASDEDIGENALLTFSIIDGDPDQKF 233

Query: 413 SITS--QNGRGLITVAQPLDFK--QERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468
           +I S     +  I + + LD++  QER + LT+   D    S  +   I + D N+ APV
Sbjct: 234 TIESDRMTNQAEIKLKKKLDYENPQERWFNLTIKVEDP-DFSSLSFCFIELQDCNDNAPV 292

Query: 469 FENAPYT--ASVFEDAPIGTTVLVVSATDSDVGINAQITYSL--SSEISNEAVAHHDQQF 524
           F  AP+   + V E+  IGT +  V A+D+D GIN QI YS+  SS++  E        F
Sbjct: 293 F-LAPFVQLSPVLENVTIGTVLTQVIASDADSGINGQIRYSIWPSSDVLGE--------F 343

Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584
            ++P  G +   K LDRE  S Y L + A D G PS + +  V  S++DVNDN P   + 
Sbjct: 344 FVDP-AGFVKVKKALDREVDSQYHLVILASDEGFPSQTGSATVSFSLLDVNDNGP---EN 399

Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNG-RIHYELDPKDREEGSFVIDP---ASGVIR 640
                I+    +  S   + A+D D   NG    + L  +      F+++     +  + 
Sbjct: 400 TAWPQIVH---MNESSDLLYASDYDTLENGPPFRFSLPSEYTNSTDFLLNDNGNNTATVH 456

Query: 641 TNKALDRESVATHDLKAVAIDGGTPPQSST 670
             +A DRE      L  +  D G PP S+T
Sbjct: 457 ALRAFDREKDKEFYLPIIITDSGNPPMSAT 486



 Score =  174 bits (423), Expect = 3e-41
 Identities = 132/415 (31%), Positives = 195/415 (46%), Gaps = 32/415 (7%)

Query: 285 DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP 344
           D G +  L Y++  K    N+    TID   G V+    LDRE    ++ +V ATD    
Sbjct: 1   DNGAHGSLKYSLHGKG-ANNI---FTIDEERGNVFVQKALDREEHGLWRFVVLATDEEGE 56

Query: 345 PRSATATXXXXXXXXXXXXXXFMPG--QYEVELAEDEPPGTPVVTLTATDADEDNR---- 398
             +  A               F          + E+ PP T V+ +TA DAD+ N     
Sbjct: 57  GLTGFADVIIYVVDINDNAPQFTCALSSCNANVYENVPPNTTVLEMTAVDADDKNEEINA 116

Query: 399 -LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQI 457
            L Y +   NT   FSI +  G  + T+   LD ++  +YVL V   D GG + T    I
Sbjct: 117 ILTYSMLN-NTMNLFSINANTGT-IYTLGN-LDREKNDKYVLLVKVIDGGGLATTGTATI 173

Query: 458 NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517
           ++ D N++ P F    + + + E   I T VL VSA+D D+G NA +T+S+   I  +  
Sbjct: 174 SVLDINDHVPRFTQDSWNSVILETNDINTKVLEVSASDEDIGENALLTFSI---IDGDP- 229

Query: 518 AHHDQQFVIN----PQTGAITTNKLLDRETMS--GYLLTVTARDGGVPSLSDTTDVEISV 571
              DQ+F I          I   K LD E      + LT+   D   P  S  +   I +
Sbjct: 230 ---DQKFTIESDRMTNQAEIKLKKKLDYENPQERWFNLTIKVED---PDFSSLSFCFIEL 283

Query: 572 VDVNDNEPVFKQQ-LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630
            D NDN PVF    +  + ++E+  +GT ++QV A+DAD G+NG+I Y + P     G F
Sbjct: 284 QDCNDNAPVFLAPFVQLSPVLENVTIGTVLTQVIASDADSGINGQIRYSIWPSSDVLGEF 343

Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685
            +DPA G ++  KALDRE  + + L  +A D G P Q+ +  V   + D+ND+ P
Sbjct: 344 FVDPA-GFVKVKKALDREVDSQYHLVILASDEGFPSQTGSATVSFSLLDVNDNGP 397



 Score =  160 bits (389), Expect = 4e-37
 Identities = 139/475 (29%), Positives = 226/475 (47%), Gaps = 57/475 (12%)

Query: 11  INVLDCNDHSPVFE--MQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68
           I V+D ND++P F   +    A+V E     TTVL + A D D  KN E+     ++T  
Sbjct: 66  IYVVDINDNAPQFTCALSSCNANVYENVPPNTTVLEMTAVDAD-DKNEEIN---AILTYS 121

Query: 69  TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
            LN                ++F I+  +G + T  +LDREK  +Y +LVK  D       
Sbjct: 122 MLN-------------NTMNLFSINANTGTIYTLGNLDREKNDKYVLLVKVIDGGG---- 164

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            L++T T  ++++D ND+ P+F++ ++   + E   +  N  + ++ A+D D+G N+ + 
Sbjct: 165 -LATTGTATISVLDINDHVPRFTQDSWNSVILETNDI--NTKVLEVSASDEDIGENALLT 221

Query: 189 YAIIGGNTQMQFSIDS----LSGDVSLVKTLDYE--QVRSYRLVIRAQDGGSPSRSNTTQ 242
           ++II G+   +F+I+S       ++ L K LDYE  Q R + L I+ +D   P  S+ + 
Sbjct: 222 FSIIDGDPDQKFTIESDRMTNQAEIKLKKKLDYENPQERWFNLTIKVED---PDFSSLSF 278

Query: 243 LLINIRDVNDNAPRFYTSLFQES-VSENVPIGYSIVRVQAYDADEGVNAELTYTM-TDKD 300
             I ++D NDNAP F     Q S V ENV IG  + +V A DAD G+N ++ Y++    D
Sbjct: 279 CFIELQDCNDNAPVFLAPFVQLSPVLENVTIGTVLTQVIASDADSGINGQIRYSIWPSSD 338

Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
             G       +DP +G+V     LDRE  ++Y L++ A+D G P ++ +AT         
Sbjct: 339 VLGE----FFVDP-AGFVKVKKALDREVDSQYHLVILASDEGFPSQTGSATVSFSLLDVN 393

Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DN--RLHYEITGGNTRGRFSITSQ 417
                       V + E          L A+D D  +N     + +    T     + + 
Sbjct: 394 DNGPENTAWPQIVHMNESSD------LLYASDYDTLENGPPFRFSLPSEYTNSTDFLLND 447

Query: 418 NGRGLITV--AQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINIT--DANNYA 466
           NG    TV   +  D ++++ + L +  TDSG    S T M+ IN     +N YA
Sbjct: 448 NGNNTATVHALRAFDREKDKEFYLPIIITDSGNPPMSATNMLLINYVCHCSNGYA 502



 Score =  145 bits (351), Expect = 2e-32
 Identities = 131/409 (32%), Positives = 189/409 (46%), Gaps = 34/409 (8%)

Query: 399 LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT--AMVQ 456
           L Y + G      F+I  +  RG + V + LD ++   +   V ATD  G   T  A V 
Sbjct: 8   LKYSLHGKGANNIFTIDEE--RGNVFVQKALDREEHGLWRFVVLATDEEGEGLTGFADVI 65

Query: 457 INITDANNYAPVFENA--PYTASVFEDAPIGTTVLVVSATDSD---VGINAQITYSLSSE 511
           I + D N+ AP F  A     A+V+E+ P  TTVL ++A D+D     INA +TYS+ + 
Sbjct: 66  IYVVDINDNAPQFTCALSSCNANVYENVPPNTTVLEMTAVDADDKNEEINAILTYSMLNN 125

Query: 512 ISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571
             N         F IN  TG I T   LDRE    Y+L V   DGG   L+ T    ISV
Sbjct: 126 TMN--------LFSINANTGTIYTLGNLDREKNDKYVLLVKVIDGG--GLATTGTATISV 175

Query: 572 VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631
           +D+ND+ P F Q  + + I+E   + T V +V A+D D+G N  + + +   D ++  F 
Sbjct: 176 LDINDHVPRFTQDSWNSVILETNDINTKVLEVSASDEDIGENALLTFSIIDGDPDQ-KFT 234

Query: 632 IDPA----SGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687
           I+         I+  K LD E+        + I    P  SS     I+++D ND+ PVF
Sbjct: 235 IESDRMTNQAEIKLKKKLDYENPQERWFN-LTIKVEDPDFSSLSFCFIELQDCNDNAPVF 293

Query: 688 ESDCLTFY-ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746
            +  +    + EN  IGT + ++ A D D G N  + YSI    D          G  K 
Sbjct: 294 LAPFVQLSPVLENVTIGTVLTQVIASDADSGINGQIRYSIWPSSDVLGEFFVDPAGFVKV 353

Query: 747 ELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAP 792
           +    +D + +S   +Y LVI A+    P       V   + DVNDN P
Sbjct: 354 K--KALDREVDS---QYHLVILASDEGFPSQTGSATVSFSLLDVNDNGP 397



 Score =  130 bits (313), Expect = 7e-28
 Identities = 99/303 (32%), Positives = 146/303 (48%), Gaps = 17/303 (5%)

Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556
           D G +  + YSL  + +N         F I+ + G +   K LDRE    +   V A D 
Sbjct: 1   DNGAHGSLKYSLHGKGANNI-------FTIDEERGNVFVQKALDREEHGLWRFVVLATDE 53

Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYT--ANIMEDALVGTSVSQVGATDAD---VG 611
               L+   DV I VVD+NDN P F   L +  AN+ E+    T+V ++ A DAD     
Sbjct: 54  EGEGLTGFADVIIYVVDINDNAPQFTCALSSCNANVYENVPPNTTVLEMTAVDADDKNEE 113

Query: 612 LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671
           +N  + Y +   +     F I+  +G I T   LDRE    + L    IDGG    + T 
Sbjct: 114 INAILTYSM--LNNTMNLFSINANTGTIYTLGNLDREKNDKYVLLVKVIDGGGLATTGTA 171

Query: 672 IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD 731
              I + DIND  P F  D     I E + I T + E+ A D D G NA++ +SI  GD 
Sbjct: 172 T--ISVLDINDHVPRFTQDSWNSVILETNDINTKVLEVSASDEDIGENALLTFSIIDGDP 229

Query: 732 SNSFSLETRQGSDKAELVTMVDLDYESPRKK-YELVIRAASPPLWNDVRVEILVTDVNDN 790
              F++E+ + +++AE+     LDYE+P+++ + L I+   P   +     I + D NDN
Sbjct: 230 DQKFTIESDRMTNQAEIKLKKKLDYENPQERWFNLTIKVEDPDFSSLSFCFIELQDCNDN 289

Query: 791 APV 793
           APV
Sbjct: 290 APV 292



 Score =  129 bits (312), Expect = 9e-28
 Identities = 126/499 (25%), Positives = 225/499 (45%), Gaps = 37/499 (7%)

Query: 88  DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
           ++F ID   G +  + +LDRE+   +  +V ATD+     + L+  A + + ++D NDN 
Sbjct: 19  NIFTIDEERGNVFVQKALDREEHGLWRFVVLATDEEG---EGLTGFADVIIYVVDINDNA 75

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD---VGANSAIRYAIIGGNTQMQFSIDS 204
           PQF+    + + +   +V  N  + ++ A DAD      N+ + Y+++  NT   FSI++
Sbjct: 76  PQFTCALSSCNANVYENVPPNTTVLEMTAVDADDKNEEINAILTYSML-NNTMNLFSINA 134

Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
            +G +  +  LD E+   Y L+++  DGG  + + T    I++ D+ND+ PRF    +  
Sbjct: 135 NTGTIYTLGNLDREKNDKYVLLVKVIDGGGLATTGTA--TISVLDINDHVPRFTQDSWNS 192

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
            + E   I   ++ V A D D G NA LT+++ D D      +          +    +L
Sbjct: 193 VILETNDINTKVLEVSASDEDIGENALLTFSIIDGDPDQKFTIESDRMTNQAEIKLKKKL 252

Query: 325 DRET-QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE-LAEDEPPG 382
           D E  Q ++  L    +  DP  S+ +               F+    ++  + E+   G
Sbjct: 253 DYENPQERWFNLTIKVE--DPDFSSLSFCFIELQDCNDNAPVFLAPFVQLSPVLENVTIG 310

Query: 383 TPVVTLTATDADE--DNRLHYEI-TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL 439
           T +  + A+DAD   + ++ Y I    +  G F +   +  G + V + LD + + +Y L
Sbjct: 311 TVLTQVIASDADSGINGQIRYSIWPSSDVLGEFFV---DPAGFVKVKKALDREVDSQYHL 367

Query: 440 TVSATDSGGRSDT--AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497
            + A+D G  S T  A V  ++ D N+  P  EN  +   V     +  +  ++ A+D D
Sbjct: 368 VILASDEGFPSQTGSATVSFSLLDVNDNGP--ENTAWPQIVH----MNESSDLLYASDYD 421

Query: 498 VGINA-QITYSLSSEISNEAVAHHDQQFVINP---QTGAITTNKLLDRETMSGYLLTVTA 553
              N     +SL SE +N         F++N     T  +   +  DRE    + L +  
Sbjct: 422 TLENGPPFRFSLPSEYTNST------DFLLNDNGNNTATVHALRAFDREKDKEFYLPIII 475

Query: 554 RDGGVPSLSDTTDVEISVV 572
            D G P +S T  + I+ V
Sbjct: 476 TDSGNPPMSATNMLLINYV 494



 Score = 63.3 bits (147), Expect = 9e-08
 Identities = 67/251 (26%), Positives = 117/251 (46%), Gaps = 39/251 (15%)

Query: 2   SVPFCIHQQINVLDCNDHSPVFEMQQYEAS-VREGASSGTTVLTLKATDQDIGKNAEVEY 60
           S+ FC    I + DCND++PVF     + S V E  + GT +  + A+D D G N ++ Y
Sbjct: 275 SLSFCF---IELQDCNDNAPVFLAPFVQLSPVLENVTIGTVLTQVIASDADSGINGQIRY 331

Query: 61  TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT 120
           +I   ++D L                   F +D  +G +  + +LDRE  ++Y +++ A+
Sbjct: 332 SI-WPSSDVLGE-----------------FFVD-PAGFVKVKKALDREVDSQYHLVILAS 372

Query: 121 DQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD 180
           D+  P     + +AT+  +++D NDN P+ +     V ++E   +        + A+D D
Sbjct: 373 DEGFPSQ---TGSATVSFSLLDVNDNGPENTAWPQIVHMNESSDL--------LYASDYD 421

Query: 181 VGANS-AIRYAIIGGNT-QMQFSIDSLSGDVSLVKTL---DYEQVRSYRLVIRAQDGGSP 235
              N    R+++    T    F ++    + + V  L   D E+ + + L I   D G+P
Sbjct: 422 TLENGPPFRFSLPSEYTNSTDFLLNDNGNNTATVHALRAFDREKDKEFYLPIIITDSGNP 481

Query: 236 SRSNTTQLLIN 246
             S T  LLIN
Sbjct: 482 PMSATNMLLIN 492


>UniRef50_UPI0000ECABB6 Cluster: Protocadherin-12 precursor
           (Vascular cadherin-2) (Vascular endothelial cadherin-2)
           (VE-cadherin-2) (VE-cad-2).; n=2; Gallus gallus|Rep:
           Protocadherin-12 precursor (Vascular cadherin-2)
           (Vascular endothelial cadherin-2) (VE-cadherin-2)
           (VE-cad-2). - Gallus gallus
          Length = 1099

 Score =  194 bits (472), Expect = 4e-47
 Identities = 183/627 (29%), Positives = 275/627 (43%), Gaps = 60/627 (9%)

Query: 92  IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151
           ++   G L T   +DRE++ R++     +      +++L+    + V ++D ND+ P+F 
Sbjct: 78  VESGDGELSTAGRVDREQLCRHSDPCWVSFDVL-AAEQLA-LIHVEVQVLDINDHAPRFP 135

Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG---- 207
                + + E  S+  +  I   +A DAD G N+   YA+   +    F+++ +SG    
Sbjct: 136 TPELELEMSESASLQMH--IPLDRALDADTGPNAHCSYAL---SPSEHFALEVVSGSDGT 190

Query: 208 ---DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
              ++ ++K +D E   S+ LV+ A D G P RS T  + + + D NDN+P F  S    
Sbjct: 191 KHAELVVIKEVDRELHSSFDLVLTAADHGEPPRSGTALIKVIVLDSNDNSPVFAESSLVV 250

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
            V E+  +G  +V V A D D+G N E+ Y+++ K     V     ID R G V     L
Sbjct: 251 EVREDALLGTLLVTVTATDPDQGPNGEIEYSLS-KHAPPEVLSTFAIDARMGSVVLRRPL 309

Query: 325 DRETQAKYQLLVTATD-GGDP-PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382
           D E    Y+L V A D G +P P                             L+E  P  
Sbjct: 310 DYEETHAYELDVQARDLGANPIPAHCKVLVRVLDVNDNAPDVRVTWAARAPVLSEAVPKD 369

Query: 383 TPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440
           + V  +TA+D D  N  R+H  ++ G+   R   T+ +   L+T A  LD +    Y LT
Sbjct: 370 SFVALVTASDPDSGNNGRVHCSLSPGDEHFRLKQTNSHSYLLMTNAM-LDRELRAEYNLT 428

Query: 441 VSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498
           + A D G  S      + I I+D N+ AP FE   Y  +V E+  +   +L V ATD D+
Sbjct: 429 LVARDQGEHSLAVWKHLTICISDVNDNAPSFERTSYERAVEENGDVPAFLLTVRATDPDL 488

Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558
           G N ++TYS+        V+       I+P +G IT  +  D E MS     VTA DGG 
Sbjct: 489 GFNGKVTYSIRDSTVLGLVS-------IDPISGDITALRAFDHEQMSSLEFLVTAEDGGH 541

Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQQ-----------LYTA------------NIMEDAL 595
           P L+    V + V+D NDN PV  +            L +A            + ME  L
Sbjct: 542 PVLASNVTVRLEVLDQNDNAPVVTEPPLVRGMATLSVLVSAETGCVWVTSGNGSAMETVL 601

Query: 596 VGTSVSQ------VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES 649
              S S       + A D D G NG + Y++   D   G  V+DP SG    N +     
Sbjct: 602 ANVSCSDTPLLFTIVARDGDSGRNGALRYDIMGGD-AAGLVVLDPLSGQAFLNASNASRL 660

Query: 650 VATHDLKAVAI-DGGTPPQSSTVIVHI 675
             T    AV I DGG  P  +   V +
Sbjct: 661 AGTQQDLAVRISDGGDEPLHTQACVRL 687



 Score =  176 bits (428), Expect = 8e-42
 Identities = 155/556 (27%), Positives = 249/556 (44%), Gaps = 24/556 (4%)

Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312
           +A    T   Q  + E VP G +++   A   + G + E+          G    P+ ++
Sbjct: 23  DAQEVATITVQYRLFEEVPEG-TVIGTLAEHFEHGESGEMGENFRLLQSPGM--FPLHVE 79

Query: 313 PRSGWVYTSGQLDRETQAKYQ-LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371
              G + T+G++DRE   ++      + D     + A                 F   + 
Sbjct: 80  SGDGELSTAGRVDREQLCRHSDPCWVSFDVLAAEQLALIHVEVQVLDINDHAPRFPTPEL 139

Query: 372 EVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNG--RGLITVAQ 427
           E+E++E       +    A DAD     H  Y ++         ++  +G     + V +
Sbjct: 140 ELEMSESASLQMHIPLDRALDADTGPNAHCSYALSPSEHFALEVVSGSDGTKHAELVVIK 199

Query: 428 PLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485
            +D +    + L ++A D G   RS TA++++ + D+N+ +PVF  +     V EDA +G
Sbjct: 200 EVDRELHSSFDLVLTAADHGEPPRSGTALIKVIVLDSNDNSPVFAESSLVVEVREDALLG 259

Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
           T ++ V+ATD D G N +I YSLS     E ++     F I+ + G++   + LD E   
Sbjct: 260 TLLVTVTATDPDQGPNGEIEYSLSKHAPPEVLS----TFAIDARMGSVVLRRPLDYEETH 315

Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP-VFKQQLYTANIMEDALVGTS-VSQV 603
            Y L V ARD G   +     V + V+DVNDN P V       A ++ +A+   S V+ V
Sbjct: 316 AYELDVQARDLGANPIPAHCKVLVRVLDVNDNAPDVRVTWAARAPVLSEAVPKDSFVALV 375

Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
            A+D D G NGR+H  L P D        +  S ++ TN  LDRE  A ++L  VA D G
Sbjct: 376 TASDPDSGNNGRVHCSLSPGDEHFRLKQTNSHSYLLMTNAMLDRELRAEYNLTLVARDQG 435

Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
               +    + I I D+ND+ P FE       + EN  +   +  +RA DPD G N  V 
Sbjct: 436 EHSLAVWKHLTICISDVNDNAPSFERTSYERAVEENGDVPAFLLTVRATDPDLGFNGKVT 495

Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRV 780
           YSI+        S++   G    ++  +   D+E      E ++ A     P L ++V V
Sbjct: 496 YSIRDSTVLGLVSIDPISG----DITALRAFDHEQ-MSSLEFLVTAEDGGHPVLASNVTV 550

Query: 781 EILVTDVNDNAPVMKD 796
            + V D NDNAPV+ +
Sbjct: 551 RLEVLDQNDNAPVVTE 566



 Score =  159 bits (386), Expect = 1e-36
 Identities = 150/550 (27%), Positives = 238/550 (43%), Gaps = 42/550 (7%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           IH ++ VLD NDH+P F   + E  + E AS    +   +A D D G NA   Y      
Sbjct: 118 IHVEVQVLDINDHAPRFPTPELELEMSESASLQMHIPLDRALDADTGPNAHCSY------ 171

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGA-LLTRASLDREKVARYTVLVKATDQASP 125
              L+P +           ++ V   DG   A L+    +DRE  + + +++ A D   P
Sbjct: 172 --ALSPSE--------HFALEVVSGSDGTKHAELVVIKEVDRELHSSFDLVLTAADHGEP 221

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
                S TA I V ++D NDN P F+E +  V V ED  +    ++  + ATD D G N 
Sbjct: 222 PR---SGTALIKVIVLDSNDNSPVFAESSLVVEVREDALL--GTLLVTVTATDPDQGPNG 276

Query: 186 AIRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
            I Y++           F+ID+  G V L + LDYE+  +Y L ++A+D G+       +
Sbjct: 277 EIEYSLSKHAPPEVLSTFAIDARMGSVVLRRPLDYEETHAYELDVQARDLGANPIPAHCK 336

Query: 243 LLINIRDVNDNAP--RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
           +L+ + DVNDNAP  R   +     +SE VP    +  V A D D G N  +  +++  D
Sbjct: 337 VLVRVLDVNDNAPDVRVTWAARAPVLSEAVPKDSFVALVTASDPDSGNNGRVHCSLSPGD 396

Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
              +  L  T +  S  + T+  LDRE +A+Y L + A D G+   +             
Sbjct: 397 --EHFRLKQT-NSHSYLLMTNAMLDRELRAEYNLTLVARDQGEHSLAVWKHLTICISDVN 453

Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQN 418
                F    YE  + E+      ++T+ ATD D   + ++ Y I      G  SI   +
Sbjct: 454 DNAPSFERTSYERAVEENGDVPAFLLTVRATDPDLGFNGKVTYSIRDSTVLGLVSIDPIS 513

Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTA 476
           G   IT  +  D +Q       V+A D G    +    V++ + D N+ APV    P   
Sbjct: 514 GD--ITALRAFDHEQMSSLEFLVTAEDGGHPVLASNVTVRLEVLDQNDNAPVVTEPPLVR 571

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
                  + T  ++VSA    V + +    ++ + ++N + +     F I  + G    N
Sbjct: 572 G------MATLSVLVSAETGCVWVTSGNGSAMETVLANVSCSDTPLLFTIVARDGDSGRN 625

Query: 537 KLLDRETMSG 546
             L  + M G
Sbjct: 626 GALRYDIMGG 635



 Score = 83.4 bits (197), Expect = 8e-14
 Identities = 74/269 (27%), Positives = 124/269 (46%), Gaps = 17/269 (6%)

Query: 632 IDPASGVIRTNKALDRESVATH-DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690
           ++   G + T   +DRE +  H D   V+ D     Q + + V +++ DIND  P F + 
Sbjct: 78  VESGDGELSTAGRVDREQLCRHSDPCWVSFDVLAAEQLALIHVEVQVLDINDHAPRFPTP 137

Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD---KAE 747
            L   +SE++ +   I   RA D D GPNA   Y++     S  F+LE   GSD    AE
Sbjct: 138 ELELEMSESASLQMHIPLDRALDADTGPNAHCSYAL---SPSEHFALEVVSGSDGTKHAE 194

Query: 748 LVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY 804
           LV + ++D E     ++LV+ AA    PP      ++++V D NDN+PV  +  ++    
Sbjct: 195 LVVIKEVDREL-HSSFDLVLTAADHGEPPRSGTALIKVIVLDSNDNSPVFAESSLVVEVR 253

Query: 805 KDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLI---LLNETTGSMTLSPQLNTNV 859
           +D         V A D D     +++Y +       ++    ++   GS+ L   L+   
Sbjct: 254 EDALLGTLLVTVTATDPDQGPNGEIEYSLSKHAPPEVLSTFAIDARMGSVVLRRPLDYEE 313

Query: 860 PKLATMEVSVTD-GVNEIKAMMQLSVRLI 887
                ++V   D G N I A  ++ VR++
Sbjct: 314 THAYELDVQARDLGANPIPAHCKVLVRVL 342



 Score = 81.0 bits (191), Expect = 4e-13
 Identities = 73/254 (28%), Positives = 109/254 (42%), Gaps = 50/254 (19%)

Query: 8   HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
           H  I + D ND++P FE   YE +V E       +LT++ATD D+G N +V Y+I     
Sbjct: 444 HLTICISDVNDNAPSFERTSYERAVEENGDVPAFLLTVRATDPDLGFNGKVTYSIR---- 499

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
                             V  +  ID  SG +    + D E+++    LV A D   PV 
Sbjct: 500 ---------------DSTVLGLVSIDPISGDITALRAFDHEQMSSLEFLVTAEDGGHPV- 543

Query: 128 DRLSSTATIHVNIIDDNDNYPQFSE-------KTYTVSVDED------------------ 162
             L+S  T+ + ++D NDN P  +E        T +V V  +                  
Sbjct: 544 --LASNVTVRLEVLDQNDNAPVVTEPPLVRGMATLSVLVSAETGCVWVTSGNGSAMETVL 601

Query: 163 --ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV 220
             +S +D P++  I A D D G N A+RY I+GG+      +D LSG   L  +      
Sbjct: 602 ANVSCSDTPLLFTIVARDGDSGRNGALRYDIMGGDAAGLVVLDPLSGQAFLNASNASRLA 661

Query: 221 RSYR-LVIRAQDGG 233
            + + L +R  DGG
Sbjct: 662 GTQQDLAVRISDGG 675


>UniRef50_Q4T6J0 Cluster: Chromosome undetermined SCAF8736, whole
           genome shotgun sequence; n=2; Tetraodontidae|Rep:
           Chromosome undetermined SCAF8736, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 1582

 Score =  192 bits (469), Expect = 9e-47
 Identities = 154/575 (26%), Positives = 263/575 (45%), Gaps = 34/575 (5%)

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
           ++ + I D+NDN+P F        +SE+   G   V  +A DAD GVN    Y++   D+
Sbjct: 91  RITVEITDINDNSPVFKYEEKLFEISESAVPGSKFVLDRAVDADIGVNGLKNYSLKPSDH 150

Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
                   T       +    QLDRE + +  LL+TA DGG+P  S T            
Sbjct: 151 FQLRMQHHTDGNNKVEMVLHKQLDREKEEEMSLLLTAVDGGEPQMSGTVKIFVTVLDVND 210

Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS-ITSQNGR 420
               F+   Y+  +AE+   GT +  ++ATDAD+        +  +T    S I + + +
Sbjct: 211 NAPVFVQPVYKAAIAENSQKGTTLTRVSATDADKGRNGEVSYSVSSTMDSVSDIFTVDEK 270

Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
           G + +   +DF++ + Y + + A DSGG SD++ V +++ D N+ AP+      + ++ E
Sbjct: 271 GDVILLGAIDFEKAKYYQIDIEARDSGGLSDSSKVIVDVIDINDNAPLISILTKSDNIPE 330

Query: 481 DAPIGTTVLVVSATDSDVGINAQ-----------ITYSLSSEISNEAVAHHDQQFVINPQ 529
           ++P  T +++ S +D D   N Q           IT  ++ +I++ A +    + VI   
Sbjct: 331 NSPPNTVIVMFSVSDPDSSNNGQMILENPMELFRITIEIT-DINDNAPSFASNEKVIEIS 389

Query: 530 TGAITTNKL-----LDRETMSGYLLTVTAR--DGGVPSLSDTTDVEISVVDVNDNEPVFK 582
             A+T +K      LD +  +  L + + +  D       +  D    + DVNDN PVF+
Sbjct: 390 ESAVTGSKFVLEKALDADIGTNGLQSYSLKPTDNFALKYENQADGGKRISDVNDNAPVFE 449

Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE---EGSFV-IDPASGV 638
           +  Y A I+E+   G S+  V A DAD   N R+ Y L+          S+V +   SGV
Sbjct: 450 RSSYQAYIVENNTPGLSIFTVRARDADWNQNARVSYILEESSVNGVPVSSYVSVSADSGV 509

Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF------ESDCL 692
           +   ++ D E +        A DGG+PP SS V V I I+D ND+PP            +
Sbjct: 510 VHAVRSFDYEQIKDFQFLVRAQDGGSPPLSSNVSVRILIQDQNDNPPQVLYPVQTGGSMV 569

Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752
              +  ++ +G  + ++ A D D G NA + Y ++   D   F +  + G  +   V  V
Sbjct: 570 AEMVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLQKATDRALFEVGLQNG--EIRTVRQV 627

Query: 753 DLDYESPRKKYELVIRAASPPLWN-DVRVEILVTD 786
             D ++ +++  +++     P  +  V V + V D
Sbjct: 628 S-DKDAVKQRLSVIVEDNGQPSRSATVIVNVAVAD 661



 Score =  178 bits (433), Expect = 2e-42
 Identities = 159/620 (25%), Positives = 263/620 (42%), Gaps = 50/620 (8%)

Query: 97  GALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT 156
           G LL +  +DRE + + T       Q   + +       I V I D NDN P F  +   
Sbjct: 55  GVLLVKDRIDREMLCKQTTPCALHLQI--ILENPMELFRITVEITDINDNSPVFKYEEKL 112

Query: 157 VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN---TQMQFSIDSLSG-DVSLV 212
             + E  S          +A DAD+G N    Y++   +    +MQ   D  +  ++ L 
Sbjct: 113 FEISE--SAVPGSKFVLDRAVDADIGVNGLKNYSLKPSDHFQLRMQHHTDGNNKVEMVLH 170

Query: 213 KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI 272
           K LD E+     L++ A DGG P  S T ++ + + DVNDNAP F   +++ +++EN   
Sbjct: 171 KQLDREKEEEMSLLLTAVDGGEPQMSGTVKIFVTVLDVNDNAPVFVQPVYKAAIAENSQK 230

Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332
           G ++ RV A DAD+G N E++Y+++      +V    T+D + G V   G +D E    Y
Sbjct: 231 GTTLTRVSATDADKGRNGEVSYSVSST--MDSVSDIFTVDEK-GDVILLGAIDFEKAKYY 287

Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392
           Q+ + A D G    S+                  +     +   E+ PP T +V  + +D
Sbjct: 288 QIDIEARDSGGLSDSSKVIVDVIDINDNAPLISILTKSDNI--PENSPPNTVIVMFSVSD 345

Query: 393 ADEDNRLHYEITGGNTRGRFSI----TSQNGRGLITVAQPLDFKQE----RRYVLTVSAT 444
            D  N     +       R +I     + N     +  + ++  +      ++VL  +  
Sbjct: 346 PDSSNNGQMILENPMELFRITIEITDINDNAPSFASNEKVIEISESAVTGSKFVLEKALD 405

Query: 445 DSGGRSDTAMVQINITD------------ANNYAPVFENAP------YTASVFEDAPIGT 486
              G +      +  TD                + V +NAP      Y A + E+   G 
Sbjct: 406 ADIGTNGLQSYSLKPTDNFALKYENQADGGKRISDVNDNAPVFERSSYQAYIVENNTPGL 465

Query: 487 TVLVVSATDSDVGINAQITYSL-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
           ++  V A D+D   NA+++Y L  S ++   V+ +     ++  +G +   +  D E + 
Sbjct: 466 SIFTVRARDADWNQNARVSYILEESSVNGVPVSSY---VSVSADSGVVHAVRSFDYEQIK 522

Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM------EDALVGTS 599
            +   V A+DGG P LS    V I + D NDN P     + T   M        A VG  
Sbjct: 523 DFQFLVRAQDGGSPPLSSNVSVRILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYL 582

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
           V++V A D D G N  + Y+L  K  +   F +   +G IRT + +  +      L  + 
Sbjct: 583 VTKVVAVDVDSGQNAWLSYKLQ-KATDRALFEVGLQNGEIRTVRQVSDKDAVKQRLSVIV 641

Query: 660 IDGGTPPQSSTVIVHIKIED 679
            D G P +S+TVIV++ + D
Sbjct: 642 EDNGQPSRSATVIVNVAVAD 661



 Score =  144 bits (350), Expect = 2e-32
 Identities = 132/453 (29%), Positives = 215/453 (47%), Gaps = 44/453 (9%)

Query: 374 ELAEDEPPGTPVVTLTATDADED-NRL-HYEIT-GGNTRGRFSI-TSQNGRGLITVAQPL 429
           E++E   PG+  V   A DAD   N L +Y +    + + R    T  N +  + + + L
Sbjct: 114 EISESAVPGSKFVLDRAVDADIGVNGLKNYSLKPSDHFQLRMQHHTDGNNKVEMVLHKQL 173

Query: 430 DFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
           D ++E    L ++A D G    S T  + + + D N+ APVF    Y A++ E++  GTT
Sbjct: 174 DREKEEEMSLLLTAVDGGEPQMSGTVKIFVTVLDVNDNAPVFVQPVYKAAIAENSQKGTT 233

Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
           +  VSATD+D G N +++YS+SS + + +       F ++ + G +     +D E    Y
Sbjct: 234 LTRVSATDADKGRNGEVSYSVSSTMDSVS-----DIFTVD-EKGDVILLGAIDFEKAKYY 287

Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
            + + ARD G   LSD++ V + V+D+NDN P+      + NI E++   T +     +D
Sbjct: 288 QIDIEARDSG--GLSDSSKVIVDVIDINDNAPLISILTKSDNIPENSPPNTVIVMFSVSD 345

Query: 608 ADVGLNG-----------RIHYELDPKDREEGSF-----VIDPASGVIRTNK-----ALD 646
            D   NG           RI  E+   +    SF     VI+ +   +  +K     ALD
Sbjct: 346 PDSSNNGQMILENPMELFRITIEITDINDNAPSFASNEKVIEISESAVTGSKFVLEKALD 405

Query: 647 RESVATHDLKAVAI---DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703
            + + T+ L++ ++   D       +      +I D+ND+ PVFE      YI EN+  G
Sbjct: 406 AD-IGTNGLQSYSLKPTDNFALKYENQADGGKRISDVNDNAPVFERSSYQAYIVENNTPG 464

Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKK 762
            +I  +RA D D   NA V Y ++    +    S      +D   +  +   DYE   K 
Sbjct: 465 LSIFTVRARDADWNQNARVSYILEESSVNGVPVSSYVSVSADSGVVHAVRSFDYEQI-KD 523

Query: 763 YELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792
           ++ ++RA    SPPL ++V V IL+ D NDN P
Sbjct: 524 FQFLVRAQDGGSPPLSSNVSVRILIQDQNDNPP 556



 Score =  137 bits (332), Expect = 4e-30
 Identities = 89/269 (33%), Positives = 129/269 (47%), Gaps = 6/269 (2%)

Query: 455  VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
            V + ITD N+ AP FE +     + E A +G   ++  A D D G N+   Y L      
Sbjct: 1293 VTVEITDINDNAPFFEKSEIRFKISESAVVGAKFVLQRAVDLDAGTNSLQGYVLKPSDHF 1352

Query: 515  EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
                H+      N +   +   K LDRE      L +TA DGG P +S T  + ++V+D 
Sbjct: 1353 ILKLHNQPDGTKNIE---MVLQKPLDREENEFISLALTAVDGGEPQMSGTMQILVTVLDA 1409

Query: 575  NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFVID 633
            NDN PVF Q +Y  +I E+A  GT V+ V A+D D  LN +I Y + +  D     F ++
Sbjct: 1410 NDNAPVFTQPVYKGSIAENAAKGTIVTSVSASDNDHDLNSKITYSITNTLDDVRRLFEVN 1469

Query: 634  PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693
              +G +R    LD E    + +   A+D G    S  VIV   + D+ND+ P+ +    +
Sbjct: 1470 EDNGEVRLTGHLDYEKKRNYQINVQAVDHGGLTDSCKVIV--DVIDVNDNKPMIKIMSKS 1527

Query: 694  FYISENSPIGTTIGEIRAHDPDEGPNAVV 722
              ISEN+   T +  I   DPD G N  V
Sbjct: 1528 AIISENATPETVVTMINIQDPDSGENGRV 1556



 Score =  135 bits (327), Expect = 1e-29
 Identities = 141/493 (28%), Positives = 213/493 (43%), Gaps = 64/493 (12%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + VLD ND++PVF    Y+A++ E +  GTT+  + ATD D G+N EV Y++   T D+ 
Sbjct: 203 VTVLDVNDNAPVFVQPVYKAAIAENSQKGTTLTRVSATDADKGRNGEVSYSVSS-TMDS- 260

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                          V D+F +D +   +L  A +D EK   Y + ++A D     S  L
Sbjct: 261 ---------------VSDIFTVDEKGDVILLGA-IDFEKAKYYQIDIEARD-----SGGL 299

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS----- 185
           S ++ + V++ID NDN P  S  T + ++ E+     N VI     +D D   N      
Sbjct: 300 SDSSKVIVDVIDINDNAPLISILTKSDNIPENSP--PNTVIVMFSVSDPDSSNNGQMILE 357

Query: 186 --------AIRYAIIGGNTQ--------MQFSIDSLSGD-VSLVKTLDYE----QVRSYR 224
                    I    I  N          ++ S  +++G    L K LD +     ++SY 
Sbjct: 358 NPMELFRITIEITDINDNAPSFASNEKVIEISESAVTGSKFVLEKALDADIGTNGLQSYS 417

Query: 225 LVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA 284
           L  +  D  +    N       I DVNDNAP F  S +Q  + EN   G SI  V+A DA
Sbjct: 418 L--KPTDNFALKYENQADGGKRISDVNDNAPVFERSSYQAYIVENNTPGLSIFTVRARDA 475

Query: 285 DEGVNAELTYTMTDKDYTG-NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD 343
           D   NA ++Y + +    G  V   +++   SG V+     D E    +Q LV A DGG 
Sbjct: 476 DWNQNARVSYILEESSVNGVPVSSYVSVSADSGVVHAVRSFDYEQIKDFQFLVRAQDGGS 535

Query: 344 PPRSATATXXXXXXXXXXXXXXFM-PGQYEVELAEDEPP-----GTPVVTLTATDADEDN 397
           PP S+  +               + P Q    +  +  P     G  V  + A D D   
Sbjct: 536 PPLSSNVSVRILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQ 595

Query: 398 R--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMV 455
              L Y++     R  F +  QNG  + TV Q  D K   +  L+V   D+G  S +A V
Sbjct: 596 NAWLSYKLQKATDRALFEVGLQNGE-IRTVRQVSD-KDAVKQRLSVIVEDNGQPSRSATV 653

Query: 456 QINITDANNYAPV 468
            +N+  A+++  V
Sbjct: 654 IVNVAVADSFPEV 666



 Score =  126 bits (303), Expect = 1e-26
 Identities = 80/232 (34%), Positives = 121/232 (52%), Gaps = 8/232 (3%)

Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE 626
           + + + D+NDN PVFK +     I E A+ G+      A DAD+G+NG  +Y L P D  
Sbjct: 92  ITVEITDINDNSPVFKYEEKLFEISESAVPGSKFVLDRAVDADIGVNGLKNYSLKPSDHF 151

Query: 627 EGSFV--IDPASGV-IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS 683
           +       D  + V +  +K LDRE      L   A+DGG P  S TV + + + D+ND+
Sbjct: 152 QLRMQHHTDGNNKVEMVLHKQLDREKEEEMSLLLTAVDGGEPQMSGTVKIFVTVLDVNDN 211

Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
            PVF        I+ENS  GTT+  + A D D+G N  V YS+    DS S   +     
Sbjct: 212 APVFVQPVYKAAIAENSQKGTTLTRVSATDADKGRNGEVSYSVSSTMDSVS---DIFTVD 268

Query: 744 DKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAPVM 794
           +K +++ +  +D+E   K Y++ I A  S  L +  +V + V D+NDNAP++
Sbjct: 269 EKGDVILLGAIDFEK-AKYYQIDIEARDSGGLSDSSKVIVDVIDINDNAPLI 319



 Score =  118 bits (284), Expect = 2e-24
 Identities = 79/285 (27%), Positives = 138/285 (48%), Gaps = 27/285 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + + D ND+SPVF+ ++    + E A  G+  +  +A D DIG N    Y        +L
Sbjct: 94  VEITDINDNSPVFKYEEKLFEISESAVPGSKFVLDRAVDADIGVNGLKNY--------SL 145

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGA-LLTRASLDREKVARYTVLVKATDQASPVSDR 129
            P D           ++     DG +   ++    LDREK    ++L+ A D   P   +
Sbjct: 146 KPSD--------HFQLRMQHHTDGNNKVEMVLHKQLDREKEEEMSLLLTAVDGGEP---Q 194

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
           +S T  I V ++D NDN P F +  Y  ++ E+        + ++ ATDAD G N  + Y
Sbjct: 195 MSGTVKIFVTVLDVNDNAPVFVQPVYKAAIAENSQ--KGTTLTRVSATDADKGRNGEVSY 252

Query: 190 AIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
           ++      +   F++D   GDV L+  +D+E+ + Y++ I A+D G    S+++++++++
Sbjct: 253 SVSSTMDSVSDIFTVDE-KGDVILLGAIDFEKAKYYQIDIEARDSG--GLSDSSKVIVDV 309

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292
            D+NDNAP        +++ EN P    IV     D D   N ++
Sbjct: 310 IDINDNAPLISILTKSDNIPENSPPNTVIVMFSVSDPDSSNNGQM 354



 Score =  117 bits (282), Expect = 4e-24
 Identities = 100/350 (28%), Positives = 154/350 (44%), Gaps = 13/350 (3%)

Query: 455  VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ-ITYSLSS-EI 512
            V + ITD N+ AP F+NA     +   A +  +V    A  S VG  AQ +   +   ++
Sbjct: 1177 VTVEITDINDNAPNFKNAEKRFEIIS-AQVSYSVPEEMAKGSLVGNIAQDLGLDVKRFKV 1235

Query: 513  SNEAVAHHDQ-QFV-INPQTGAITTNKLLDRETMSGYLLTVTARDGGV-PSLSDTTDVEI 569
             N  V   D  +++ ++   G +   + +DRE + G +         V  +  +   V +
Sbjct: 1236 GNARVYSGDSMEYIELDRDRGVLLIKERIDREALCGEVTPCAVHFQIVLENPMEFYSVTV 1295

Query: 570  SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629
             + D+NDN P F++      I E A+VG       A D D G N    Y L P D     
Sbjct: 1296 EITDINDNAPFFEKSEIRFKISESAVVGAKFVLQRAVDLDAGTNSLQGYVLKPSDHFILK 1355

Query: 630  FVIDPASGV---IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686
                P       +   K LDRE      L   A+DGG P  S T+ + + + D ND+ PV
Sbjct: 1356 LHNQPDGTKNIEMVLQKPLDREENEFISLALTAVDGGEPQMSGTMQILVTVLDANDNAPV 1415

Query: 687  FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746
            F        I+EN+  GT +  + A D D   N+ + YSI    D      E  +  D  
Sbjct: 1416 FTQPVYKGSIAENAAKGTIVTSVSASDNDHDLNSKITYSITNTLDDVRRLFEVNE--DNG 1473

Query: 747  ELVTMVDLDYESPRKKYELVIRAAS-PPLWNDVRVEILVTDVNDNAPVMK 795
            E+     LDYE  ++ Y++ ++A     L +  +V + V DVNDN P++K
Sbjct: 1474 EVRLTGHLDYEK-KRNYQINVQAVDHGGLTDSCKVIVDVIDVNDNKPMIK 1522



 Score =  116 bits (279), Expect = 9e-24
 Identities = 77/273 (28%), Positives = 130/273 (47%), Gaps = 8/273 (2%)

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
            + I D+NDNAP F  S  +  +SE+  +G   V  +A D D G N+   Y +   D+   
Sbjct: 1295 VEITDINDNAPFFEKSEIRFKISESAVVGAKFVLQRAVDLDAGTNSLQGYVLKPSDHF-I 1353

Query: 305  VDLPITID-PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
            + L    D  ++  +     LDRE      L +TA DGG+P  S T              
Sbjct: 1354 LKLHNQPDGTKNIEMVLQKPLDREENEFISLALTAVDGGEPQMSGTMQILVTVLDANDNA 1413

Query: 364  XXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITG--GNTRGRFSITSQNG 419
              F    Y+  +AE+   GT V +++A+D D D  +++ Y IT    + R  F +   NG
Sbjct: 1414 PVFTQPVYKGSIAENAAKGTIVTSVSASDNDHDLNSKITYSITNTLDDVRRLFEVNEDNG 1473

Query: 420  RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479
               + +   LD++++R Y + V A D GG +D+  V +++ D N+  P+ +    +A + 
Sbjct: 1474 E--VRLTGHLDYEKKRNYQINVQAVDHGGLTDSCKVIVDVIDVNDNKPMIKIMSKSAIIS 1531

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512
            E+A   T V +++  D D G N ++   ++  I
Sbjct: 1532 ENATPETVVTMINIQDPDSGENGRVQCFITENI 1564



 Score =  110 bits (265), Expect = 5e-22
 Identities = 67/196 (34%), Positives = 105/196 (53%), Gaps = 9/196 (4%)

Query: 423  ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480
            + + +PLD ++     L ++A D G    S T  + + + DAN+ APVF    Y  S+ E
Sbjct: 1368 MVLQKPLDREENEFISLALTAVDGGEPQMSGTMQILVTVLDANDNAPVFTQPVYKGSIAE 1427

Query: 481  DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
            +A  GT V  VSA+D+D  +N++ITYS+++ + +       + F +N   G +     LD
Sbjct: 1428 NAAKGTIVTSVSASDNDHDLNSKITYSITNTLDDVR-----RLFEVNEDNGEVRLTGHLD 1482

Query: 541  RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
             E    Y + V A D G   L+D+  V + V+DVNDN+P+ K    +A I E+A   T V
Sbjct: 1483 YEKKRNYQINVQAVDHG--GLTDSCKVIVDVIDVNDNKPMIKIMSKSAIISENATPETVV 1540

Query: 601  SQVGATDADVGLNGRI 616
            + +   D D G NGR+
Sbjct: 1541 TMINIQDPDSGENGRV 1556



 Score =  108 bits (259), Expect = 2e-21
 Identities = 70/230 (30%), Positives = 112/230 (48%), Gaps = 11/230 (4%)

Query: 457  INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL-SSEISNE 515
            + I+D N+ APVFE + Y A + E+   G ++  V A D+D   NA+++Y L  S ++  
Sbjct: 800  LEISDVNDNAPVFERSSYQAYIVENNSPGLSIFTVRARDADWSQNARVSYILEESSVNGV 859

Query: 516  AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575
             V+ +     ++  +G +   +  D E +  +   V A+DGG P LS    V I + D N
Sbjct: 860  PVSSY---VSVSADSGVVHAVRSFDYEQIKDFHFLVRAQDGGSPPLSSNVSVRILIQDQN 916

Query: 576  DNEPVFKQQLYTANIM------EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629
            DN P     + T   M        A VG  V++V A D D G N  + Y+L  K  +   
Sbjct: 917  DNPPQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLQ-KATDRAL 975

Query: 630  FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679
            F +   +G IRT + +  +      L  +  D G P +S+TVIV++ + D
Sbjct: 976  FEVGLQNGEIRTVRQVSDKDAVKQRLSVIVEDNGQPSRSATVIVNVAVAD 1025



 Score =  105 bits (252), Expect = 2e-20
 Identities = 71/223 (31%), Positives = 110/223 (49%), Gaps = 17/223 (7%)

Query: 138  VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY-----AII 192
            + I D NDN P F   +Y   + E+ S      I  ++A DAD   N+ + Y     ++ 
Sbjct: 800  LEISDVNDNAPVFERSSYQAYIVENNS--PGLSIFTVRARDADWSQNARVSYILEESSVN 857

Query: 193  GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252
            G       S+ + SG V  V++ DYEQ++ +  ++RAQDGGSP  S+   + I I+D ND
Sbjct: 858  GVPVSSYVSVSADSGVVHAVRSFDYEQIKDFHFLVRAQDGGSPPLSSNVSVRILIQDQND 917

Query: 253  NAPR-FYT-----SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
            N P+  Y      S+  E V  +  +GY + +V A D D G NA L+Y +         +
Sbjct: 918  NPPQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLQKATDRALFE 977

Query: 307  LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT 349
            + +    ++G + T  Q+  +   K +L V   D G P RSAT
Sbjct: 978  VGL----QNGEIRTVRQVSDKDAVKQRLSVIVEDNGQPSRSAT 1016



 Score =  103 bits (248), Expect = 5e-20
 Identities = 75/259 (28%), Positives = 118/259 (45%), Gaps = 10/259 (3%)

Query: 88   DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
            +   +D   G LL +  +DRE +           Q   V +      ++ V I D NDN 
Sbjct: 1247 EYIELDRDRGVLLIKERIDREALCGEVTPCAVHFQI--VLENPMEFYSVTVEITDINDNA 1304

Query: 148  PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN---TQMQFSIDS 204
            P F +      + E   V    V+ +  A D D G NS   Y +   +    ++    D 
Sbjct: 1305 PFFEKSEIRFKISESAVVGAKFVLQR--AVDLDAGTNSLQGYVLKPSDHFILKLHNQPDG 1362

Query: 205  LSG-DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263
                ++ L K LD E+     L + A DGG P  S T Q+L+ + D NDNAP F   +++
Sbjct: 1363 TKNIEMVLQKPLDREENEFISLALTAVDGGEPQMSGTMQILVTVLDANDNAPVFTQPVYK 1422

Query: 264  ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323
             S++EN   G  +  V A D D  +N+++TY++T+     +V     ++  +G V  +G 
Sbjct: 1423 GSIAENAAKGTIVTSVSASDNDHDLNSKITYSITNT--LDDVRRLFEVNEDNGEVRLTGH 1480

Query: 324  LDRETQAKYQLLVTATDGG 342
            LD E +  YQ+ V A D G
Sbjct: 1481 LDYEKKRNYQINVQAVDHG 1499



 Score =  102 bits (244), Expect = 2e-19
 Identities = 75/291 (25%), Positives = 133/291 (45%), Gaps = 26/291 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + + D ND++P FE  +    + E A  G   +  +A D D G N+   Y         L
Sbjct: 1295 VEITDINDNAPFFEKSEIRFKISESAVVGAKFVLQRAVDLDAGTNSLQGYV--------L 1346

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGA-LLTRASLDREKVARYTVLVKATDQASPVSDR 129
             P D                + DG     ++ +  LDRE+    ++ + A D   P   +
Sbjct: 1347 KPSDHFILKLHN--------QPDGTKNIEMVLQKPLDREENEFISLALTAVDGGEP---Q 1395

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            +S T  I V ++D NDN P F++  Y  S+ E+ +     ++  + A+D D   NS I Y
Sbjct: 1396 MSGTMQILVTVLDANDNAPVFTQPVYKGSIAENAA--KGTIVTSVSASDNDHDLNSKITY 1453

Query: 190  AIIG--GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            +I     + +  F ++  +G+V L   LDYE+ R+Y++ ++A D G    +++ ++++++
Sbjct: 1454 SITNTLDDVRRLFEVNEDNGEVRLTGHLDYEKKRNYQINVQAVDHGG--LTDSCKVIVDV 1511

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
             DVNDN P          +SEN      +  +   D D G N  +   +T+
Sbjct: 1512 IDVNDNKPMIKIMSKSAIISENATPETVVTMINIQDPDSGENGRVQCFITE 1562



 Score = 95.1 bits (226), Expect = 2e-17
 Identities = 69/238 (28%), Positives = 112/238 (47%), Gaps = 14/238 (5%)

Query: 560  SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619
            S+ D  D  + + DVNDN PVF++  Y A I+E+   G S+  V A DAD   N R+ Y 
Sbjct: 791  SILDEPDSPLEISDVNDNAPVFERSSYQAYIVENNSPGLSIFTVRARDADWSQNARVSYI 850

Query: 620  LDPKDRE---EGSFV-IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675
            L+          S+V +   SGV+   ++ D E +        A DGG+PP SS V V I
Sbjct: 851  LEESSVNGVPVSSYVSVSADSGVVHAVRSFDYEQIKDFHFLVRAQDGGSPPLSSNVSVRI 910

Query: 676  KIEDINDSPPVF------ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729
             I+D ND+PP            +   +  ++ +G  + ++ A D D G NA + Y ++  
Sbjct: 911  LIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLQKA 970

Query: 730  DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN-DVRVEILVTD 786
             D   F +  + G  +   V  V  D ++ +++  +++     P  +  V V + V D
Sbjct: 971  TDRALFEVGLQNG--EIRTVRQVS-DKDAVKQRLSVIVEDNGQPSRSATVIVNVAVAD 1025



 Score = 95.1 bits (226), Expect = 2e-17
 Identities = 67/243 (27%), Positives = 113/243 (46%), Gaps = 21/243 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            + + D ND++PVFE   Y+A + E  S G ++ T++A D D  +NA V Y +E  + + +
Sbjct: 800  LEISDVNDNAPVFERSSYQAYIVENNSPGLSIFTVRARDADWSQNARVSYILEESSVNGV 859

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           V     +   SG +    S D E++  +  LV+A D  SP    L
Sbjct: 860  P--------------VSSYVSVSADSGVVHAVRSFDYEQIKDFHFLVRAQDGGSPP---L 902

Query: 131  SSTATIHVNIIDDNDNYPQ--FSEKTYTVSVDEDI--SVTDNPVIAKIKATDADVGANSA 186
            SS  ++ + I D NDN PQ  +  +T    V E +  S     ++ K+ A D D G N+ 
Sbjct: 903  SSNVSVRILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQNAW 962

Query: 187  IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
            + Y +     +  F +   +G++  V+ +  +     RL +  +D G PSRS T  + + 
Sbjct: 963  LSYKLQKATDRALFEVGLQNGEIRTVRQVSDKDAVKQRLSVIVEDNGQPSRSATVIVNVA 1022

Query: 247  IRD 249
            + D
Sbjct: 1023 VAD 1025



 Score = 84.2 bits (199), Expect = 5e-14
 Identities = 70/233 (30%), Positives = 102/233 (43%), Gaps = 11/233 (4%)

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG- 303
            + I DVNDNAP F  S +Q  + EN   G SI  V+A DAD   NA ++Y + +    G 
Sbjct: 800  LEISDVNDNAPVFERSSYQAYIVENNSPGLSIFTVRARDADWSQNARVSYILEESSVNGV 859

Query: 304  NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363
             V   +++   SG V+     D E    +  LV A DGG PP S+  +            
Sbjct: 860  PVSSYVSVSADSGVVHAVRSFDYEQIKDFHFLVRAQDGGSPPLSSNVSVRILIQDQNDNP 919

Query: 364  XXFM-PGQYEVELAEDEPP-----GTPVVTLTATDADEDNR--LHYEITGGNTRGRFSIT 415
               + P Q    +  +  P     G  V  + A D D      L Y++     R  F + 
Sbjct: 920  PQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLQKATDRALFEVG 979

Query: 416  SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468
             QNG  + TV Q  D K   +  L+V   D+G  S +A V +N+  A+++  V
Sbjct: 980  LQNGE-IRTVRQVSD-KDAVKQRLSVIVEDNGQPSRSATVIVNVAVADSFPEV 1030



 Score = 68.5 bits (160), Expect = 2e-09
 Identities = 43/122 (35%), Positives = 62/122 (50%), Gaps = 5/122 (4%)

Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN- 733
           ++I D+ND+ PVFE      YI EN+  G +I  +RA D D   NA V Y ++    +  
Sbjct: 800 LEISDVNDNAPVFERSSYQAYIVENNSPGLSIFTVRARDADWSQNARVSYILEESSVNGV 859

Query: 734 SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDN 790
             S      +D   +  +   DYE   K +  ++RA    SPPL ++V V IL+ D NDN
Sbjct: 860 PVSSYVSVSADSGVVHAVRSFDYEQI-KDFHFLVRAQDGGSPPLSSNVSVRILIQDQNDN 918

Query: 791 AP 792
            P
Sbjct: 919 PP 920



 Score = 37.9 bits (84), Expect = 4.0
 Identities = 27/100 (27%), Positives = 47/100 (47%), Gaps = 6/100 (6%)

Query: 779 RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNN 836
           R+ + +TD+NDN+PV K  + +F   +   P   F    A DAD  V     Y +   ++
Sbjct: 91  RITVEITDINDNSPVFKYEEKLFEISESAVPGSKFVLDRAVDADIGVNGLKNYSLKPSDH 150

Query: 837 ANLILLNETTGS----MTLSPQLNTNVPKLATMEVSVTDG 872
             L + + T G+    M L  QL+    +  ++ ++  DG
Sbjct: 151 FQLRMQHHTDGNNKVEMVLHKQLDREKEEEMSLLLTAVDG 190


>UniRef50_Q4RRF3 Cluster: Chromosome 16 SCAF15002, whole genome
           shotgun sequence; n=5; Clupeocephala|Rep: Chromosome 16
           SCAF15002, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 421

 Score =  191 bits (465), Expect = 3e-46
 Identities = 140/421 (33%), Positives = 211/421 (50%), Gaps = 27/421 (6%)

Query: 176 ATDADVGANSAIRYAIIGGNTQMQFSIDSLSG-------DVSLVKTLDYEQVRSYRLVIR 228
           A DAD G  +   Y I  GN    F++++  G       D+ +   LD E+  +Y L + 
Sbjct: 11  AVDADQGQLTTQGYLIKDGNVGQAFTLETRRGSNGVLYLDLVVNTILDREKRSTYTLSLE 70

Query: 229 AQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV 288
           A DGGSP R++   L I ++D+NDNAP F  S +   +SEN+  G +I++V A D DEG 
Sbjct: 71  AFDGGSPKRTDVMSLDITVQDINDNAPVFNQSRYHAIISENLQPGSNILQVFATDDDEGD 130

Query: 289 NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348
           N ++ Y +  +    + D    ID +SG +  +  LD E +  ++L+V A D    P  +
Sbjct: 131 NGKVLYEINRRQ--SDPDRYFVIDSQSGVITLNKPLDFEMKRVHELVVQAQDNATQPEVS 188

Query: 349 TATXXXXXXXXX----XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYE 402
            A                   F+       ++E   PG  V  ++ TD D  E   ++  
Sbjct: 189 NAFVTIHVRDYNDNQPTMTIIFLSEDGSPRVSEGAQPGQYVARISVTDPDYGEYANVNVS 248

Query: 403 ITGGNTRGRFSITSQ-NGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQIN 458
           + GG+  G+F++T++ N   LI V + LD ++   Y L V ATDSG    R++++ + I 
Sbjct: 249 LEGGD--GKFALTTKDNIIYLICVDRILDREERDTYELRVMATDSGTPPLRAESSFI-IQ 305

Query: 459 ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518
           +TD N+  P+F+   Y   + E    G+ VL V+A D D G N  ITYSL  +       
Sbjct: 306 VTDVNDNPPLFDQPVYRQVIPEVVFPGSFVLQVTARDKDHGPNGDITYSLFQD-----QG 360

Query: 519 HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578
            H + F I+  TG ITT+  LD E      +TV A DGG P +S T  V I + D+NDNE
Sbjct: 361 AHSKWFSIDSVTGIITTDSQLDYEKNPNPSITVVATDGGKPPMSSTALVNIVLQDINDNE 420

Query: 579 P 579
           P
Sbjct: 421 P 421



 Score =  187 bits (456), Expect = 3e-45
 Identities = 144/423 (34%), Positives = 204/423 (48%), Gaps = 30/423 (7%)

Query: 281 AYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR---SGWVY----TSGQLDRETQAKYQ 333
           A DAD+G      Y + D    GNV    T++ R   +G +Y     +  LDRE ++ Y 
Sbjct: 11  AVDADQGQLTTQGYLIKD----GNVGQAFTLETRRGSNGVLYLDLVVNTILDREKRSTYT 66

Query: 334 LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393
           L + A DGG P R+   +              F   +Y   ++E+  PG+ ++ + ATD 
Sbjct: 67  LSLEAFDGGSPKRTDVMSLDITVQDINDNAPVFNQSRYHAIISENLQPGSNILQVFATDD 126

Query: 394 DE-DN-RLHYEITG--GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR 449
           DE DN ++ YEI     +    F I SQ+G  +IT+ +PLDF+ +R + L V A D+  +
Sbjct: 127 DEGDNGKVLYEINRRQSDPDRYFVIDSQSG--VITLNKPLDFEMKRVHELVVQAQDNATQ 184

Query: 450 SDT--AMVQINITDANNYAP----VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503
            +   A V I++ D N+  P    +F +   +  V E A  G  V  +S TD D G  A 
Sbjct: 185 PEVSNAFVTIHVRDYNDNQPTMTIIFLSEDGSPRVSEGAQPGQYVARISVTDPDYGEYAN 244

Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD 563
           +  SL       A+   D    +      I  +++LDRE    Y L V A D G P L  
Sbjct: 245 VNVSLEGGDGKFALTTKDNIIYL------ICVDRILDREERDTYELRVMATDSGTPPLRA 298

Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DP 622
            +   I V DVNDN P+F Q +Y   I E    G+ V QV A D D G NG I Y L   
Sbjct: 299 ESSFIIQVTDVNDNPPLFDQPVYRQVIPEVVFPGSFVLQVTARDKDHGPNGDITYSLFQD 358

Query: 623 KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND 682
           +      F ID  +G+I T+  LD E      +  VA DGG PP SST +V+I ++DIND
Sbjct: 359 QGAHSKWFSIDSVTGIITTDSQLDYEKNPNPSITVVATDGGKPPMSSTALVNIVLQDIND 418

Query: 683 SPP 685
           + P
Sbjct: 419 NEP 421



 Score =  182 bits (442), Expect = 2e-43
 Identities = 133/428 (31%), Positives = 206/428 (48%), Gaps = 26/428 (6%)

Query: 382 GTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNG-RGLI----TVAQPLDFKQE 434
           GT      A DAD+       Y I  GN    F++ ++ G  G++     V   LD ++ 
Sbjct: 3   GTRFPLEPAVDADQGQLTTQGYLIKDGNVGQAFTLETRRGSNGVLYLDLVVNTILDREKR 62

Query: 435 RRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492
             Y L++ A D G   R+D   + I + D N+ APVF  + Y A + E+   G+ +L V 
Sbjct: 63  STYTLSLEAFDGGSPKRTDVMSLDITVQDINDNAPVFNQSRYHAIISENLQPGSNILQVF 122

Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552
           ATD D G N ++ Y ++   S+      D+ FVI+ Q+G IT NK LD E    + L V 
Sbjct: 123 ATDDDEGDNGKVLYEINRRQSDP-----DRYFVIDSQSGVITLNKPLDFEMKRVHELVVQ 177

Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEP----VFKQQLYTANIMEDALVGTSVSQVGATDA 608
           A+D           V I V D NDN+P    +F  +  +  + E A  G  V+++  TD 
Sbjct: 178 AQDNATQPEVSNAFVTIHVRDYNDNQPTMTIIFLSEDGSPRVSEGAQPGQYVARISVTDP 237

Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
           D G    ++  L+  D +      D    +I  ++ LDRE   T++L+ +A D GTPP  
Sbjct: 238 DYGEYANVNVSLEGGDGKFALTTKDNIIYLICVDRILDREERDTYELRVMATDSGTPPLR 297

Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-- 726
           +     I++ D+ND+PP+F+       I E    G+ + ++ A D D GPN  + YS+  
Sbjct: 298 AESSFIIQVTDVNDNPPLFDQPVYRQVIPEVVFPGSFVLQVTARDKDHGPNGDITYSLFQ 357

Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPRKKYELVIR-AASPPLWNDVRVEILV 784
             G  S  FS+++  G     + T   LDYE +P     +V      PP+ +   V I++
Sbjct: 358 DQGAHSKWFSIDSVTGI----ITTDSQLDYEKNPNPSITVVATDGGKPPMSSTALVNIVL 413

Query: 785 TDVNDNAP 792
            D+NDN P
Sbjct: 414 QDINDNEP 421



 Score =  169 bits (411), Expect = 1e-39
 Identities = 124/354 (35%), Positives = 178/354 (50%), Gaps = 20/354 (5%)

Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592
           +  N +LDRE  S Y L++ A DGG P  +D   ++I+V D+NDN PVF Q  Y A I E
Sbjct: 51  LVVNTILDREKRSTYTLSLEAFDGGSPKRTDVMSLDITVQDINDNAPVFNQSRYHAIISE 110

Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNKALDRESVA 651
           +   G+++ QV ATD D G NG++ YE++ +  + +  FVID  SGVI  NK LD E   
Sbjct: 111 NLQPGSNILQVFATDDDEGDNGKVLYEINRRQSDPDRYFVIDSQSGVITLNKPLDFEMKR 170

Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP----VFESDCLTFYISENSPIGTTIG 707
            H+L   A D  T P+ S   V I + D ND+ P    +F S+  +  +SE +  G  + 
Sbjct: 171 VHELVVQAQDNATQPEVSNAFVTIHVRDYNDNQPTMTIIFLSEDGSPRVSEGAQPGQYVA 230

Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
            I   DPD G  A V+ S++GGD    F+L T+        V  + LD E  R  YEL +
Sbjct: 231 RISVTDPDYGEYANVNVSLEGGD--GKFALTTKDNIIYLICVDRI-LDREE-RDTYELRV 286

Query: 768 RA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY--KDCFPVGPFGRVPAYDAD 822
            A    +PPL  +    I VTDVNDN P+    Q ++     +  FP     +V A D D
Sbjct: 287 MATDSGTPPLRAESSFIIQVTDVNDNPPLFD--QPVYRQVIPEVVFPGSFVLQVTARDKD 344

Query: 823 --VTDKLQYRIL--SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
                 + Y +    G ++    ++  TG +T   QL+       ++ V  TDG
Sbjct: 345 HGPNGDITYSLFQDQGAHSKWFSIDSVTGIITTDSQLDYEKNPNPSITVVATDG 398



 Score =  144 bits (350), Expect = 2e-32
 Identities = 118/382 (30%), Positives = 177/382 (46%), Gaps = 24/382 (6%)

Query: 99  LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158
           L+    LDREK + YT+ ++A D  SP   + +   ++ + + D NDN P F++  Y   
Sbjct: 51  LVVNTILDREKRSTYTLSLEAFDGGSP---KRTDVMSLDITVQDINDNAPVFNQSRYHAI 107

Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAI--IGGNTQMQFSIDSLSGDVSLVKTLD 216
           + E++    N  I ++ ATD D G N  + Y I     +    F IDS SG ++L K LD
Sbjct: 108 ISENLQPGSN--ILQVFATDDDEGDNGKVLYEINRRQSDPDRYFVIDSQSGVITLNKPLD 165

Query: 217 YEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES----VSENVPI 272
           +E  R + LV++AQD  +    +   + I++RD NDN P        E     VSE    
Sbjct: 166 FEMKRVHELVVQAQDNATQPEVSNAFVTIHVRDYNDNQPTMTIIFLSEDGSPRVSEGAQP 225

Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332
           G  + R+   D D G  A +  ++   D  G   L  T D     +     LDRE +  Y
Sbjct: 226 GQYVARISVTDPDYGEYANVNVSLEGGD--GKFAL-TTKDNIIYLICVDRILDREERDTY 282

Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392
           +L V ATD G PP  A ++              F    Y   + E   PG+ V+ +TA D
Sbjct: 283 ELRVMATDSGTPPLRAESSFIIQVTDVNDNPPLFDQPVYRQVIPEVVFPGSFVLQVTARD 342

Query: 393 ADE--DNRLHYEI---TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447
            D   +  + Y +    G +++  FSI S    G+IT    LD+++     +TV ATD G
Sbjct: 343 KDHGPNGDITYSLFQDQGAHSKW-FSIDSVT--GIITTDSQLDYEKNPNPSITVVATDGG 399

Query: 448 --GRSDTAMVQINITDANNYAP 467
               S TA+V I + D N+  P
Sbjct: 400 KPPMSSTALVNIVLQDINDNEP 421



 Score =  143 bits (347), Expect = 5e-32
 Identities = 104/343 (30%), Positives = 165/343 (48%), Gaps = 25/343 (7%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V D ND++PVF   +Y A + E    G+ +L + ATD D G N +V Y I    +D  
Sbjct: 87  ITVQDINDNAPVFNQSRYHAIISENLQPGSNILQVFATDDDEGDNGKVLYEINRRQSD-- 144

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            P+                F ID +SG +     LD E    + ++V+A D A+   +  
Sbjct: 145 -PD--------------RYFVIDSQSGVITLNKPLDFEMKRVHELVVQAQDNATQ-PEVS 188

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP--VIAKIKATDADVGANSAIR 188
           ++  TIHV   D NDN P  +    +      +S    P   +A+I  TD D G  + + 
Sbjct: 189 NAFVTIHVR--DYNDNQPTMTIIFLSEDGSPRVSEGAQPGQYVARISVTDPDYGEYANVN 246

Query: 189 YAIIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            ++ GG+ +   +  D++   + + + LD E+  +Y L + A D G+P     +  +I +
Sbjct: 247 VSLEGGDGKFALTTKDNIIYLICVDRILDREERDTYELRVMATDSGTPPLRAESSFIIQV 306

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            DVNDN P F   ++++ + E V  G  +++V A D D G N ++TY++      G    
Sbjct: 307 TDVNDNPPLFDQPVYRQVIPEVVFPGSFVLQVTARDKDHGPNGDITYSLFQDQ--GAHSK 364

Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350
             +ID  +G + T  QLD E      + V ATDGG PP S+TA
Sbjct: 365 WFSIDSVTGIITTDSQLDYEKNPNPSITVVATDGGKPPMSSTA 407



 Score = 56.4 bits (130), Expect = 1e-05
 Identities = 53/184 (28%), Positives = 84/184 (45%), Gaps = 11/184 (5%)

Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA---ELVTMVDLDYES 758
           IGT      A D D+G      Y IK G+   +F+LETR+GS+     +LV    LD E 
Sbjct: 2   IGTRFPLEPAVDADQGQLTTQGYLIKDGNVGQAFTLETRRGSNGVLYLDLVVNTILDREK 61

Query: 759 PRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR 815
            R  Y L + A    SP   + + ++I V D+NDNAPV    +      ++  P     +
Sbjct: 62  -RSTYTLSLEAFDGGSPKRTDVMSLDITVQDINDNAPVFNQSRYHAIISENLQPGSNILQ 120

Query: 816 VPAYDADVTD--KLQYRI--LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
           V A D D  D  K+ Y I     +     +++  +G +TL+  L+  + ++  + V   D
Sbjct: 121 VFATDDDEGDNGKVLYEINRRQSDPDRYFVIDSQSGVITLNKPLDFEMKRVHELVVQAQD 180

Query: 872 GVNE 875
              +
Sbjct: 181 NATQ 184


>UniRef50_Q9NPG4 Cluster: Protocadherin-12 precursor; n=16;
           Theria|Rep: Protocadherin-12 precursor - Homo sapiens
           (Human)
          Length = 1184

 Score =  190 bits (463), Expect = 5e-46
 Identities = 143/500 (28%), Positives = 235/500 (47%), Gaps = 23/500 (4%)

Query: 198 MQFSIDSLSGDVSLVKTLDYEQV-RSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256
           +   +DS  G +S  + LD EQ+ R +   + + D  +        + I + D+ND+ PR
Sbjct: 75  LPIQVDSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPR 134

Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP-RS 315
           F     +  +SE+  +   I   +A D D G N   TYT++  ++   +D+ +  D  + 
Sbjct: 135 FPKGEQELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFA-LDVIVGPDETKH 193

Query: 316 GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375
             +    +LDRE  + + L++TA D G+PP+S T+               F      +E+
Sbjct: 194 AELIVVKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEI 253

Query: 376 AEDEPPGTPVVTLTATDADEDNRLHYEI-----TGGNTRGRFSITSQNGRGLITVAQPLD 430
            ED  PGT ++ LTATD D+      E              FSI ++ G+  + + +PLD
Sbjct: 254 QEDAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQ--VILRRPLD 311

Query: 431 FKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFEN--APYTASVFEDAPIGT 486
           +++   Y + V A D G     A   V I + D N+  P      A   + V E  P  +
Sbjct: 312 YEKNPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDS 371

Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546
            + +V A D D G N  +   LS E+       H +    N  T  + TN  LDRE    
Sbjct: 372 FIALVMADDLDSGHNGLVHCWLSQELG------HFRLKRTNGNTYMLLTNATLDREQWPK 425

Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
           Y LT+ A+D G+  LS    + I + D+NDN PVF++  Y  +  E+ L    +  + A 
Sbjct: 426 YTLTLLAQDQGLQPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAH 485

Query: 607 DADVGLNGRIHYELDPKDREEGSFV-IDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
           DAD+G+NG++ Y +  +D      V ID  +G +   ++L+ E +A  + + +A D G P
Sbjct: 486 DADLGINGKVSYRI--QDSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQP 543

Query: 666 PQSSTVIVHIKIEDINDSPP 685
             +S+V V + + D ND+ P
Sbjct: 544 MLASSVSVWVSLLDANDNAP 563



 Score =  173 bits (422), Expect = 4e-41
 Identities = 141/503 (28%), Positives = 227/503 (45%), Gaps = 31/503 (6%)

Query: 91  RIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNI--IDDNDNYP 148
           ++D   G L T   LDRE++ R       +       D     A IHV I  +D ND+ P
Sbjct: 78  QVDSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGD----LALIHVEIQVLDINDHQP 133

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG- 207
           +F +    + + E  S+     I   +A D D G N+   Y +   +    F++D + G 
Sbjct: 134 RFPKGEQELEISESASLRTR--IPLDRALDPDTGPNTLHTYTL---SPSEHFALDVIVGP 188

Query: 208 ------DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261
                 ++ +VK LD E    + LV+ A D G+P +S T+ + +N+ D NDN+P F  S 
Sbjct: 189 DETKHAELIVVKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESS 248

Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321
               + E+   G  ++++ A D D+G N E+ + ++ K     V    +ID ++G V   
Sbjct: 249 LALEIQEDAAPGTLLIKLTATDPDQGPNGEVEFFLS-KHMPPEVLDTFSIDAKTGQVILR 307

Query: 322 GQLDRETQAKYQLLVTATD-GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380
             LD E    Y++ V A D G +P  +                   +    +  L  +  
Sbjct: 308 RPLDYEKNPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEAL 367

Query: 381 PGTPVVTLT-ATDADEDNRLHYEITGGNTRGRFSITSQNGRG-LITVAQPLDFKQERRYV 438
           P    + L  A D D  +            G F +   NG   ++     LD +Q  +Y 
Sbjct: 368 PKDSFIALVMADDLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYT 427

Query: 439 LTVSATDSGGRSDTAMVQ--INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496
           LT+ A D G +  +A  Q  I I+D N+ APVFE + Y  S  E+      ++ + A D+
Sbjct: 428 LTLLAQDQGLQPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDA 487

Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556
           D+GIN +++Y     I +  VAH      I+  TG +T  + L+ E M+G+   V A D 
Sbjct: 488 DLGINGKVSY----RIQDSPVAH---LVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDS 540

Query: 557 GVPSLSDTTDVEISVVDVNDNEP 579
           G P L+ +  V +S++D NDN P
Sbjct: 541 GQPMLASSVSVWVSLLDANDNAP 563



 Score =  164 bits (399), Expect = 3e-38
 Identities = 140/500 (28%), Positives = 229/500 (45%), Gaps = 25/500 (5%)

Query: 307 LPITIDPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
           LPI +D   G + T  +LDRE   + +   + + D       A                 
Sbjct: 75  LPIQVDSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPR 134

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSIT---SQNGRG 421
           F  G+ E+E++E     T +    A D D   N LH      +      +     +    
Sbjct: 135 FPKGEQELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHA 194

Query: 422 LITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVF 479
            + V + LD +    + L ++A D+G   +S T++V++N+ D+N+ +P F  +     + 
Sbjct: 195 ELIVVKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQ 254

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           EDA  GT ++ ++ATD D G N ++ + LS  +  E +      F I+ +TG +   + L
Sbjct: 255 EDAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVL----DTFSIDAKTGQVILRRPL 310

Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP-VFKQQLYTANIMEDALVGT 598
           D E    Y + V ARD G   +     V I V+DVNDN P +        +++ +AL   
Sbjct: 311 DYEKNPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKD 370

Query: 599 S-VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG---VIRTNKALDRESVATHD 654
           S ++ V A D D G NG +H  L    +E G F +   +G   ++ TN  LDRE    + 
Sbjct: 371 SFIALVMADDLDSGHNGLVHCWLS---QELGHFRLKRTNGNTYMLLTNATLDREQWPKYT 427

Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
           L  +A D G  P S+   + I+I DIND+ PVFE         EN+     +  I+AHD 
Sbjct: 428 LTLLAQDQGLQPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDA 487

Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIR-AASP 772
           D G N  V Y I+    ++  ++++  G    E+     L+YE     +++++   +  P
Sbjct: 488 DLGINGKVSYRIQDSPVAHLVAIDSNTG----EVTAQRSLNYEEMAGFEFQVIAEDSGQP 543

Query: 773 PLWNDVRVEILVTDVNDNAP 792
            L + V V + + D NDNAP
Sbjct: 544 MLASSVSVWVSLLDANDNAP 563



 Score =  163 bits (396), Expect = 6e-38
 Identities = 141/497 (28%), Positives = 222/497 (44%), Gaps = 39/497 (7%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           IH +I VLD NDH P F   + E  + E AS  T +   +A D D G N    YT     
Sbjct: 119 IHVEIQVLDINDHQPRFPKGEQELEISESASLRTRIPLDRALDPDTGPNTLHTYT----- 173

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
              L+P +              V   + +   L+    LDRE  + + +++ A D  +P 
Sbjct: 174 ---LSPSEHFALDVI-------VGPDETKHAELIVVKELDREIHSFFDLVLTAYDNGNPP 223

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
               S T+ + VN++D NDN P F+E +  + + ED       ++ K+ ATD D G N  
Sbjct: 224 K---SGTSLVKVNVLDSNDNSPAFAESSLALEIQED--AAPGTLLIKLTATDPDQGPNGE 278

Query: 187 IRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243
           + + +   +       FSID+ +G V L + LDYE+  +Y + ++A+D G        ++
Sbjct: 279 VEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAYEVDVQARDLGPNPIPAHCKV 338

Query: 244 LINIRDVNDNAPRFYTSLFQES--VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
           LI + DVNDN P  + +   +   VSE +P    I  V A D D G N  L +    ++ 
Sbjct: 339 LIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIALVMADDLDSGHNG-LVHCWLSQE- 396

Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
            G+  L  T +  +  + T+  LDRE   KY L + A D G  P SA             
Sbjct: 397 LGHFRLKRT-NGNTYMLLTNATLDREQWPKYTLTLLAQDQGLQPLSAKKQLSIQISDIND 455

Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419
               F   +YEV   E+  P   ++T+ A DAD   + ++ Y I         +I S  G
Sbjct: 456 NAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSYRIQDSPVAHLVAIDSNTG 515

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTAS 477
              +T  + L++++   +   V A DSG    + +  V +++ DAN+ AP          
Sbjct: 516 E--VTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWVSLLDANDNAP-----EVVQP 568

Query: 478 VFEDAPIGTTVLVVSAT 494
           V  D     +VLV ++T
Sbjct: 569 VLSDGKASLSVLVNAST 585



 Score =  161 bits (390), Expect = 3e-37
 Identities = 133/451 (29%), Positives = 208/451 (46%), Gaps = 25/451 (5%)

Query: 421 GLITVAQPLDFKQE-RRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTAS 477
           GL++  + LD +Q  R++   + + D     D A+  V+I + D N++ P F        
Sbjct: 84  GLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGEQELE 143

Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT---GAIT 534
           + E A + T + +  A D D G N   TY+LS         H     ++ P       + 
Sbjct: 144 ISESASLRTRIPLDRALDPDTGPNTLHTYTLSPS------EHFALDVIVGPDETKHAELI 197

Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
             K LDRE  S + L +TA D G P  S T+ V+++V+D NDN P F +      I EDA
Sbjct: 198 VVKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDA 257

Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREE--GSFVIDPASGVIRTNKALDRESVAT 652
             GT + ++ ATD D G NG + + L      E   +F ID  +G +   + LD E    
Sbjct: 258 APGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPA 317

Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT--FYISENSPIGTTIGEIR 710
           +++   A D G  P  +   V IK+ D+ND+ P       +    +SE  P  + I  + 
Sbjct: 318 YEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIALVM 377

Query: 711 AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770
           A D D G N +VH  +    +   F L+   G+    L+T   LD E    KY L + A 
Sbjct: 378 ADDLDSGHNGLVHCWLS--QELGHFRLKRTNGNTYM-LLTNATLDREQ-WPKYTLTLLAQ 433

Query: 771 SP---PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTD 825
                PL    ++ I ++D+NDNAPV +  +   +  ++  P      + A+DAD  +  
Sbjct: 434 DQGLQPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGING 493

Query: 826 KLQYRILSGNNANLILLNETTGSMTLSPQLN 856
           K+ YRI     A+L+ ++  TG +T    LN
Sbjct: 494 KVSYRIQDSPVAHLVAIDSNTGEVTAQRSLN 524



 Score =  100 bits (240), Expect = 5e-19
 Identities = 62/195 (31%), Positives = 104/195 (53%), Gaps = 10/195 (5%)

Query: 91  RIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQF 150
           R +G +  LLT A+LDRE+  +YT+ + A DQ       LS+   + + I D NDN P F
Sbjct: 404 RTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGL---QPLSAKKQLSIQISDINDNAPVF 460

Query: 151 SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVS 210
            +  Y VS  E+ ++    +I  IKA DAD+G N  + Y I         +IDS +G+V+
Sbjct: 461 EKSRYEVSTREN-NLPSLHLIT-IKAHDADLGINGKVSYRIQDSPVAHLVAIDSNTGEVT 518

Query: 211 LVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE-----S 265
             ++L+YE++  +   + A+D G P  +++  + +++ D NDNAP     +  +     S
Sbjct: 519 AQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWVSLLDANDNAPEVVQPVLSDGKASLS 578

Query: 266 VSENVPIGYSIVRVQ 280
           V  N   G+ +V ++
Sbjct: 579 VLVNASTGHLLVPIE 593


>UniRef50_Q6R0H9 Cluster: Cadherin-related neuronal receptor c01;
           n=4; Gallus gallus|Rep: Cadherin-related neuronal
           receptor c01 - Gallus gallus (Chicken)
          Length = 948

 Score =  188 bits (458), Expect = 2e-45
 Identities = 145/508 (28%), Positives = 241/508 (47%), Gaps = 30/508 (5%)

Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLV-IRAQDGGSPSRS 238
           +  A SA ++ +I G+++  F+I++ +G +S+ + +D EQ+   +   +   +    +  
Sbjct: 302 NAAALSARKFRMIIGSSKQYFNINATTGVLSVNEPIDREQLCELKSTCLLNYELVLENPL 361

Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
              ++   + DVNDN+P F  S ++ SV E +  G       A D DEG N    Y +  
Sbjct: 362 ELYRMEFKVLDVNDNSPSFPLSEYRVSVPEFLSPGARFALPNAQDLDEGTNGVQNYILNP 421

Query: 299 KDYTGNVDLPITIDPRSGWVYTS----GQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354
            ++  ++++ +  D   G VY        LDRE QA ++L++ A DGGDPPRS       
Sbjct: 422 DEHF-HLEMQMRGD---GSVYPELVLKKALDREQQATHRLVLIAEDGGDPPRSGDVPVIV 477

Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI---TGGNTR 409
                      F    Y   + E+ P GT VV + ATD DE  +  + Y     T  + +
Sbjct: 478 TVLDTNDNAPEFEQSVYRASVLENSPSGTLVVRVHATDLDEGPNGEVRYSFSNATAADLQ 537

Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAP 467
             F I    G   +TV+  L  ++    +L + A D G    S TA + + ITD NN+ P
Sbjct: 538 QMFLIHPHTGE--VTVSGDLAVQRPLLEML-IEARDKGAFALSSTAKLLVEITDVNNHGP 594

Query: 468 VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527
               A  +  + EDA  GT + ++S  D D G N ++T  +   +  +     +  +   
Sbjct: 595 EITIASLSNPIPEDAVPGTVIALLSIVDKDPGENGKVTCQIPDNLPFQLKPSLENYY--- 651

Query: 528 PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT 587
               ++ T+ LLDRE +SGY +T+TA D G P ++    + + + DVNDN PVF    + 
Sbjct: 652 ----SLITSGLLDRELISGYNITITATDLGSPPITTQQTLWVQISDVNDNPPVFAADTFD 707

Query: 588 ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG---SFV-IDPASGVIRTNK 643
             + E+  +G  + QV A+D D+G NG+I Y L           SF+ +   +G I   +
Sbjct: 708 VFVEENNPLGAFLYQVSASDLDIGENGQISYILRNSTVAGSALTSFLSVSLVNGSIYAKR 767

Query: 644 ALDRESVATHDLKAVAIDGGTPPQSSTV 671
           A D E + +   +  A D G+P  S+ +
Sbjct: 768 AFDFEQLRSFHFQVEAKDNGSPALSAAM 795



 Score =  184 bits (449), Expect = 2e-44
 Identities = 145/482 (30%), Positives = 225/482 (46%), Gaps = 20/482 (4%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F I+  +G L     +DRE++           +   V +       +   ++D NDN P 
Sbjct: 322 FNINATTGVLSVNEPIDREQLCELKSTCLLNYEL--VLENPLELYRMEFKVLDVNDNSPS 379

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG---NTQMQFSID-SL 205
           F    Y VSV E +S       A   A D D G N    Y +      + +MQ   D S+
Sbjct: 380 FPLSEYRVSVPEFLS--PGARFALPNAQDLDEGTNGVQNYILNPDEHFHLEMQMRGDGSV 437

Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265
             ++ L K LD EQ  ++RLV+ A+DGG P RS    +++ + D NDNAP F  S+++ S
Sbjct: 438 YPELVLKKALDREQQATHRLVLIAEDGGDPPRSGDVPVIVTVLDTNDNAPEFEQSVYRAS 497

Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325
           V EN P G  +VRV A D DEG N E+ Y+ ++     ++     I P +G V  SG L 
Sbjct: 498 VLENSPSGTLVVRVHATDLDEGPNGEVRYSFSNAT-AADLQQMFLIHPHTGEVTVSGDLA 556

Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
            + +   ++L+ A D G    S+TA                        + ED  PGT +
Sbjct: 557 VQ-RPLLEMLIEARDKGAFALSSTAKLLVEITDVNNHGPEITIASLSNPIPEDAVPGTVI 615

Query: 386 VTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443
             L+  D D  E+ ++  +I   N   +   + +N   LIT +  LD +    Y +T++A
Sbjct: 616 ALLSIVDKDPGENGKVTCQIP-DNLPFQLKPSLENYYSLIT-SGLLDRELISGYNITITA 673

Query: 444 TDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501
           TD G    T    + + I+D N+  PVF    +   V E+ P+G  +  VSA+D D+G N
Sbjct: 674 TDLGSPPITTQQTLWVQISDVNDNPPVFAADTFDVFVEENNPLGAFLYQVSASDLDIGEN 733

Query: 502 AQITYSL-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560
            QI+Y L +S ++  A+       ++N   G+I   +  D E +  +   V A+D G P+
Sbjct: 734 GQISYILRNSTVAGSALTSFLSVSLVN---GSIYAKRAFDFEQLRSFHFQVEAKDNGSPA 790

Query: 561 LS 562
           LS
Sbjct: 791 LS 792



 Score =  167 bits (407), Expect = 3e-39
 Identities = 116/377 (30%), Positives = 188/377 (49%), Gaps = 16/377 (4%)

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQ-NGRGLI 423
           F   +Y V + E   PG       A D DE  N +   I   N    F +  Q  G G +
Sbjct: 380 FPLSEYRVSVPEFLSPGARFALPNAQDLDEGTNGVQNYIL--NPDEHFHLEMQMRGDGSV 437

Query: 424 ----TVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTAS 477
                + + LD +Q+  + L + A D G   RS    V + + D N+ AP FE + Y AS
Sbjct: 438 YPELVLKKALDREQQATHRLVLIAEDGGDPPRSGDVPVIVTVLDTNDNAPEFEQSVYRAS 497

Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537
           V E++P GT V+ V ATD D G N ++ YS S    N   A   Q F+I+P TG +T + 
Sbjct: 498 VLENSPSGTLVVRVHATDLDEGPNGEVRYSFS----NATAADLQQMFLIHPHTGEVTVSG 553

Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597
            L  +     +L + ARD G  +LS T  + + + DVN++ P       +  I EDA+ G
Sbjct: 554 DLAVQRPLLEML-IEARDKGAFALSSTAKLLVEITDVNNHGPEITIASLSNPIPEDAVPG 612

Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657
           T ++ +   D D G NG++  ++      +    ++    +I T+  LDRE ++ +++  
Sbjct: 613 TVIALLSIVDKDPGENGKVTCQIPDNLPFQLKPSLENYYSLI-TSGLLDRELISGYNITI 671

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
            A D G+PP ++   + ++I D+ND+PPVF +D    ++ EN+P+G  + ++ A D D G
Sbjct: 672 TATDLGSPPITTQQTLWVQISDVNDNPPVFAADTFDVFVEENNPLGAFLYQVSASDLDIG 731

Query: 718 PNAVVHYSIKGGDDSNS 734
            N  + Y ++    + S
Sbjct: 732 ENGQISYILRNSTVAGS 748



 Score =  149 bits (362), Expect = 8e-34
 Identities = 126/452 (27%), Positives = 202/452 (44%), Gaps = 45/452 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +  VLD ND+SP F + +Y  SV E  S G       A D D G N    Y         
Sbjct: 367 EFKVLDVNDNSPSFPLSEYRVSVPEFLSPGARFALPNAQDLDEGTNGVQNY--------I 418

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGR-SGALLTRASLDREKVARYTVLVKATDQASPVSD 128
           LNP++           ++   R DG     L+ + +LDRE+ A + +++ A D   P   
Sbjct: 419 LNPDE--------HFHLEMQMRGDGSVYPELVLKKALDREQQATHRLVLIAEDGGDPPR- 469

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             S    + V ++D NDN P+F +  Y  SV E  +     ++ ++ ATD D G N  +R
Sbjct: 470 --SGDVPVIVTVLDTNDNAPEFEQSVYRASVLE--NSPSGTLVVRVHATDLDEGPNGEVR 525

Query: 189 YAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
           Y+       + Q  F I   +G+V++   L  ++     ++I A+D G+ + S+T +LL+
Sbjct: 526 YSFSNATAADLQQMFLIHPHTGEVTVSGDLAVQR-PLLEMLIEARDKGAFALSSTAKLLV 584

Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305
            I DVN++ P    +     + E+   G  I  +   D D G N ++T  + D       
Sbjct: 585 EITDVNNHGPEITIASLSNPIPEDAVPGTVIALLSIVDKDPGENGKVTCQIPD------- 637

Query: 306 DLPITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
           +LP  + P     Y   TSG LDRE  + Y + +TATD G PP +   T           
Sbjct: 638 NLPFQLKPSLENYYSLITSGLLDRELISGYNITITATDLGSPPITTQQTLWVQISDVNDN 697

Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGR-----FSIT 415
              F    ++V + E+ P G  +  ++A+D D  E+ ++ Y +      G       S++
Sbjct: 698 PPVFAADTFDVFVEENNPLGAFLYQVSASDLDIGENGQISYILRNSTVAGSALTSFLSVS 757

Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447
             NG   I   +  DF+Q R +   V A D+G
Sbjct: 758 LVNGS--IYAKRAFDFEQLRSFHFQVEAKDNG 787



 Score =  139 bits (336), Expect = 1e-30
 Identities = 108/344 (31%), Positives = 157/344 (45%), Gaps = 27/344 (7%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + VLD ND++P FE   Y ASV E + SGT V+ + ATD D G N EV Y+    TA  L
Sbjct: 477 VTVLDTNDNAPEFEQSVYRASVLENSPSGTLVVRVHATDLDEGPNGEVRYSFSNATAADL 536

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           Q +F I   +G +     L  ++     +L++A D+    +  L
Sbjct: 537 ----------------QQMFLIHPHTGEVTVSGDLAVQR-PLLEMLIEARDKG---AFAL 576

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           SSTA + V I D N++ P+ +  + +  + ED       VIA +   D D G N  +   
Sbjct: 577 SSTAKLLVEITDVNNHGPEITIASLSNPIPED--AVPGTVIALLSIVDKDPGENGKVT-C 633

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            I  N   Q    SL    SL+ +  LD E +  Y + I A D GSP  +    L + I 
Sbjct: 634 QIPDNLPFQLK-PSLENYYSLITSGLLDRELISGYNITITATDLGSPPITTQQTLWVQIS 692

Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN-VDL 307
           DVNDN P F    F   V EN P+G  + +V A D D G N +++Y + +    G+ +  
Sbjct: 693 DVNDNPPVFAADTFDVFVEENNPLGAFLYQVSASDLDIGENGQISYILRNSTVAGSALTS 752

Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
            +++   +G +Y     D E    +   V A D G P  SA  T
Sbjct: 753 FLSVSLVNGSIYAKRAFDFEQLRSFHFQVEAKDNGSPALSAAMT 796



 Score =  127 bits (307), Expect = 4e-27
 Identities = 103/326 (31%), Positives = 148/326 (45%), Gaps = 22/326 (6%)

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
           S+ E    GT V  V+    D+GINA    +LS+      +    Q F IN  TG ++ N
Sbjct: 281 SIAEGTDRGTFVGNVA---KDLGINAA---ALSARKFRMIIGSSKQYFNINATTGVLSVN 334

Query: 537 KLLDRETMSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
           + +DRE +     T     +  + +  +   +E  V+DVNDN P F    Y  ++ E   
Sbjct: 335 EPIDREQLCELKSTCLLNYELVLENPLELYRMEFKVLDVNDNSPSFPLSEYRVSVPEFLS 394

Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV---IRTNKALDRESVAT 652
            G   +   A D D G NG  +Y L+P +       +     V   +   KALDRE  AT
Sbjct: 395 PGARFALPNAQDLDEGTNGVQNYILNPDEHFHLEMQMRGDGSVYPELVLKKALDREQQAT 454

Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
           H L  +A DGG PP+S  V V + + D ND+ P FE       + ENSP GT +  + A 
Sbjct: 455 HRLVLIAEDGGDPPRSGDVPVIVTVLDTNDNAPEFEQSVYRASVLENSPSGTLVVRVHAT 514

Query: 713 DPDEGPNAVVHYSIK---GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
           D DEGPN  V YS       D    F +    G    E+    DL  + P    E++I A
Sbjct: 515 DLDEGPNGEVRYSFSNATAADLQQMFLIHPHTG----EVTVSGDLAVQRP--LLEMLIEA 568

Query: 770 ASP---PLWNDVRVEILVTDVNDNAP 792
                  L +  ++ + +TDVN++ P
Sbjct: 569 RDKGAFALSSTAKLLVEITDVNNHGP 594



 Score =  126 bits (304), Expect = 9e-27
 Identities = 112/389 (28%), Positives = 176/389 (45%), Gaps = 18/389 (4%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           ++  + D N+ +P F  + Y  SV E    G    + +A D D G N    Y L+ +   
Sbjct: 366 MEFKVLDVNDNSPSFPLSEYRVSVPEFLSPGARFALPNAQDLDEGTNGVQNYILNPDEHF 425

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
                      + P+   +   K LDRE  + + L + A DGG P  S    V ++V+D 
Sbjct: 426 HLEMQMRGDGSVYPE---LVLKKALDREQQATHRLVLIAEDGGDPPRSGDVPVIVTVLDT 482

Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE--GSFVI 632
           NDN P F+Q +Y A+++E++  GT V +V ATD D G NG + Y        +    F+I
Sbjct: 483 NDNAPEFEQSVYRASVLENSPSGTLVVRVHATDLDEGPNGEVRYSFSNATAADLQQMFLI 542

Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692
            P +G +  +  L  +     ++   A D G    SST  + ++I D+N+  P      L
Sbjct: 543 HPHTGEVTVSGDLAVQRPLL-EMLIEARDKGAFALSSTAKLLVEITDVNNHGPEITIASL 601

Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752
           +  I E++  GT I  +   D D G N  V   I    D+  F L+     +   L+T  
Sbjct: 602 SNPIPEDAVPGTVIALLSIVDKDPGENGKVTCQIP---DNLPFQLKPSL-ENYYSLITSG 657

Query: 753 DLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVM-KDFQIIFNNYKDCF 808
            LD E     Y + I A    SPP+     + + ++DVNDN PV   D   +F   ++  
Sbjct: 658 LLDRELI-SGYNITITATDLGSPPITTQQTLWVQISDVNDNPPVFAADTFDVF--VEENN 714

Query: 809 PVGPF-GRVPAYDADVTDKLQYRILSGNN 836
           P+G F  +V A D D+ +  Q   +  N+
Sbjct: 715 PLGAFLYQVSASDLDIGENGQISYILRNS 743


>UniRef50_Q4SM61 Cluster: Chromosome 13 SCAF14555, whole genome
            shotgun sequence; n=5; Clupeocephala|Rep: Chromosome 13
            SCAF14555, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 1382

 Score =  188 bits (458), Expect = 2e-45
 Identities = 224/879 (25%), Positives = 363/879 (41%), Gaps = 97/879 (11%)

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLI 423
            F    YE  + E    GT V+ ++A D D   + ++ Y +   ++            G+I
Sbjct: 9    FTSSIYEASVTEGAQIGTSVLQVSAHDKDLGLNGQITYTLLSDSSGDHSLFRIDPELGII 68

Query: 424  TVAQPLDFKQERRYVLTVSATDSG-----GR-----SDTAMVQINITDANNYAPVFENAP 473
                  D +    Y+L V + D       G+     SDTA V++ I+D N+  PVF    
Sbjct: 69   YTEAVFDREARSSYLLEVQSEDGQESARPGKNKQPNSDTAYVRVFISDVNDNKPVFAQRL 128

Query: 474  YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533
            Y   V EDA +G  V+ VSATD D G NA++ Y ++S        +    F I P+ G I
Sbjct: 129  YEVGVDEDADVGLAVVTVSATDEDEGANAKLRYQITS-------GNKGGVFDIEPEVGTI 181

Query: 534  TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593
               + LD E    Y L V A DG      D   + ++VV+ ND  PVF    Y  ++ E+
Sbjct: 182  FVAQPLDYEQQKRYKLLVLASDG---RWEDYAAIVVTVVNKNDEAPVFSMNEYYGSVTEE 238

Query: 594  ALVGTSVSQVGATDA-----DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648
             L G+ V  +   D      +   +  +   L P+D   G+ +I   +    T+  L+ E
Sbjct: 239  -LDGSPVFVLQIDDENDNAPEFASSSHLLPPL-PEDVPVGTSIIQVVA--TDTDSGLNGE 294

Query: 649  SVAT----HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
             + +     D        GTP  +++V VH+ + D ND+ P  E+      + ENSP   
Sbjct: 295  ILYSILPQSDPHGHFATAGTPALTASVTVHLLLLDTNDNGPELET-AYAPVLWENSPAPQ 353

Query: 705  TI----GEIRAH--DPDEGPNAVVHYSIKGGDDSNSFSLETR-QGSDKAELVTMVDLDYE 757
             +         H  D D   N   +Y       S  F L+    GS     + M D + +
Sbjct: 354  VVWLNQSSTLLHVVDRDSPENGPPYYLSLPSLYSVDFHLQDHGNGSAMLTALRMFDRERQ 413

Query: 758  SPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVP 817
            S      +++ +  PP+     + I + D NDNA    +  +  ++ K        G+V 
Sbjct: 414  SEFHLPVIMVDSGDPPMTATNTLTITIGDQNDNAHQAGEKDVYVHSRKGRVGNAALGKVY 473

Query: 818  AYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLAT-MEVSVTDGV-NE 875
            A D D  D   Y  L  + A    LN+++G +T+      N P  +  + V V+DGV  +
Sbjct: 474  APDPDDWDNKTYT-LETSAAKYFSLNQSSGELTI----RQNAPAGSYWLRVGVSDGVWPD 528

Query: 876  IKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPL------LGFFIDGLAAIIPCPKE 929
            + + +++ VR + E+ +L+S ++RL  +TA  F+         L  F D L+  +     
Sbjct: 529  VISGIRVHVRDLEEKAVLSSASLRLTGLTARDFIDSRIEGKSRLETFWDFLSETLSVRTG 588

Query: 930  NIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARL 989
            +I IFSV D    T   ++V F      AE G       +  P  L   +  H+  L  L
Sbjct: 589  SINIFSVADREQKT---VDVHFYVL---AENG-------YLHPEKLHAVLAAHKRKLQSL 635

Query: 990  ATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEG 1049
              V V   + + CVH  C     C T L   N+   ++S ++    +       C C   
Sbjct: 636  LRVNVSQVEVDECVHADCRASGGCFTQLSVSNSPSLLDSGALSLVSVKVTPVAVCGC--- 692

Query: 1050 FTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCELRARS 1109
                     +T   C     G+ C +G  C+  + G      C     +    C+    S
Sbjct: 693  -----AAREMTYRIC-ASYPGNPCLNGGTCMDTKNG----YRCHCPPQFDGPDCQQTRLS 742

Query: 1110 FPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRY-----NERHDFLALELVSSEA 1164
            F  + +   P ++     HL L+F T    GLLLY G        +  D++A+EL+    
Sbjct: 743  FLGNGYAWLPPIRPCFDSHLSLEFMTDEDDGLLLYAGPLATLLPGDTEDYMAIELI---- 798

Query: 1165 GRGGGPGLRFSFSLGGGKSEITVEGNVG--DGSWHTVEI 1201
              GG P L+ +   G G   + +  N+G  +G WH +++
Sbjct: 799  --GGTPSLKMNH--GSGTLVLQLNHNIGVANGRWHRLDV 833



 Score =  182 bits (442), Expect = 2e-43
 Identities = 151/496 (30%), Positives = 231/496 (46%), Gaps = 39/496 (7%)

Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
           DVNDN P F +S+++ SV+E   IG S+++V A+D D G+N ++TYT+   D +G+  L 
Sbjct: 1   DVNDNVPFFTSSIYEASVTEGAQIGTSVLQVSAHDKDLGLNGQITYTLLS-DSSGDHSL- 58

Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD--------PPRSATATXXXXXXXXX 360
             IDP  G +YT    DRE ++ Y L V + DG +         P S TA          
Sbjct: 59  FRIDPELGIIYTEAVFDREARSSYLLEVQSEDGQESARPGKNKQPNSDTAYVRVFISDVN 118

Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQN 418
                F    YEV + ED   G  VVT++ATD DE  + +L Y+IT GN  G F I  + 
Sbjct: 119 DNKPVFAQRLYEVGVDEDADVGLAVVTVSATDEDEGANAKLRYQITSGNKGGVFDIEPE- 177

Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASV 478
             G I VAQPLD++Q++RY L V A+D G   D A + + + + N+ APVF    Y  SV
Sbjct: 178 -VGTIFVAQPLDYEQQKRYKLLVLASD-GRWEDYAAIVVTVVNKNDEAPVFSMNEYYGSV 235

Query: 479 FEDAPIGTTVLVVSATDSDVGIN--AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
            E+   G+ V V+   D +      A  ++ L     +  V     Q V       +   
Sbjct: 236 TEELD-GSPVFVLQIDDENDNAPEFASSSHLLPPLPEDVPVGTSIIQVVATDTDSGLNGE 294

Query: 537 ---KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593
               +L +    G+  T      G P+L+ +  V + ++D NDN P   +  Y   + E+
Sbjct: 295 ILYSILPQSDPHGHFAT-----AGTPALTASVTVHLLLLDTNDNGPEL-ETAYAPVLWEN 348

Query: 594 A------LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG--VIRTNKAL 645
           +       +  S + +   D D   NG  +Y   P        + D  +G  ++   +  
Sbjct: 349 SPAPQVVWLNQSSTLLHVVDRDSPENGPPYYLSLPSLYSVDFHLQDHGNGSAMLTALRMF 408

Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP-PVFESDCLTFYISENSPIG- 703
           DRE  +   L  + +D G PP ++T  + I I D ND+     E D   +  S    +G 
Sbjct: 409 DRERQSEFHLPVIMVDSGDPPMTATNTLTITIGDQNDNAHQAGEKD--VYVHSRKGRVGN 466

Query: 704 TTIGEIRAHDPDEGPN 719
             +G++ A DPD+  N
Sbjct: 467 AALGKVYAPDPDDWDN 482



 Score =  137 bits (332), Expect = 4e-30
 Identities = 91/261 (34%), Positives = 135/261 (51%), Gaps = 27/261 (10%)

Query: 15  DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
           D ND+ P F    YEASV EGA  GT+VL + A D+D+G N ++ YT+    +D+     
Sbjct: 1   DVNDNVPFFTSSIYEASVTEGAQIGTSVLQVSAHDKDLGLNGQITYTL---LSDSSGD-- 55

Query: 75  AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD---QASPVSDRL- 130
                         +FRID   G + T A  DRE  + Y + V++ D    A P  ++  
Sbjct: 56  ------------HSLFRIDPELGIIYTEAVFDREARSSYLLEVQSEDGQESARPGKNKQP 103

Query: 131 -SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            S TA + V I D NDN P F+++ Y V VDED  V     +  + ATD D GAN+ +RY
Sbjct: 104 NSDTAYVRVFISDVNDNKPVFAQRLYEVGVDEDADV--GLAVVTVSATDEDEGANAKLRY 161

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            I  GN    F I+   G + + + LDYEQ + Y+L++ A DG      +   +++ + +
Sbjct: 162 QITSGNKGGVFDIEPEVGTIFVAQPLDYEQQKRYKLLVLASDG---RWEDYAAIVVTVVN 218

Query: 250 VNDNAPRFYTSLFQESVSENV 270
            ND AP F  + +  SV+E +
Sbjct: 219 KNDEAPVFSMNEYYGSVTEEL 239



 Score =  136 bits (330), Expect = 6e-30
 Identities = 83/231 (35%), Positives = 119/231 (51%), Gaps = 16/231 (6%)

Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFV 631
           DVNDN P F   +Y A++ E A +GTSV QV A D D+GLNG+I Y L      +   F 
Sbjct: 1   DVNDNVPFFTSSIYEASVTEGAQIGTSVLQVSAHDKDLGLNGQITYTLLSDSSGDHSLFR 60

Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDG--------GTPPQSSTVIVHIKIEDINDS 683
           IDP  G+I T    DRE+ +++ L+  + DG           P S T  V + I D+ND+
Sbjct: 61  IDPELGIIYTEAVFDREARSSYLLEVQSEDGQESARPGKNKQPNSDTAYVRVFISDVNDN 120

Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
            PVF        + E++ +G  +  + A D DEG NA + Y I  G+    F +E   G+
Sbjct: 121 KPVFAQRLYEVGVDEDADVGLAVVTVSATDEDEGANAKLRYQITSGNKGGVFDIEPEVGT 180

Query: 744 DKAELVTMVDLDYESPRKKYELVIRAASPPLWND-VRVEILVTDVNDNAPV 793
               +     LDYE  +K+Y+L++  AS   W D   + + V + ND APV
Sbjct: 181 ----IFVAQPLDYEQ-QKRYKLLV-LASDGRWEDYAAIVVTVVNKNDEAPV 225



 Score =  126 bits (303), Expect = 1e-26
 Identities = 144/562 (25%), Positives = 236/562 (41%), Gaps = 51/562 (9%)

Query: 142 DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNT--QMQ 199
           D NDN P F+   Y  SV E   +  +  + ++ A D D+G N  I Y ++  ++     
Sbjct: 1   DVNDNVPFFTSSIYEASVTEGAQIGTS--VLQVSAHDKDLGLNGQITYTLLSDSSGDHSL 58

Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR--------SNTTQLLINIRDVN 251
           F ID   G +      D E   SY L ++++DG   +R        S+T  + + I DVN
Sbjct: 59  FRIDPELGIIYTEAVFDREARSSYLLEVQSEDGQESARPGKNKQPNSDTAYVRVFISDVN 118

Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311
           DN P F   L++  V E+  +G ++V V A D DEG NA+L Y +T    +GN      I
Sbjct: 119 DNKPVFAQRLYEVGVDEDADVGLAVVTVSATDEDEGANAKLRYQIT----SGNKGGVFDI 174

Query: 312 DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371
           +P  G ++ +  LD E Q +Y+LLV A+DG     +A                 F   +Y
Sbjct: 175 EPEVGTIFVAQPLDYEQQKRYKLLVLASDGRWEDYAAIVV---TVVNKNDEAPVFSMNEY 231

Query: 372 EVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI-TVAQPLD 430
              + E E  G+PV  L   D + DN   +  +  +           G  +I  VA   D
Sbjct: 232 YGSVTE-ELDGSPVFVLQIDD-ENDNAPEF-ASSSHLLPPLPEDVPVGTSIIQVVATDTD 288

Query: 431 FKQERRYVLTV-SATDSGGRSDTA---------MVQINITDANNYAPVFENAPYTASVFE 480
                  + ++   +D  G   TA          V + + D N+  P  E A Y   ++E
Sbjct: 289 SGLNGEILYSILPQSDPHGHFATAGTPALTASVTVHLLLLDTNDNGPELETA-YAPVLWE 347

Query: 481 DAP------IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534
           ++P      +  +  ++   D D   N    Y LS   S  +V  H Q       +  +T
Sbjct: 348 NSPAPQVVWLNQSSTLLHVVDRDSPENGP-PYYLSLP-SLYSVDFHLQDH--GNGSAMLT 403

Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
             ++ DRE  S + L V   D G P ++ T  + I++ D NDN     ++    +  +  
Sbjct: 404 ALRMFDRERQSEFHLPVIMVDSGDPPMTATNTLTITIGDQNDNAHQAGEKDVYVHSRKGR 463

Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654
           +   ++ +V A D D   N    Y L+    +   F ++ +SG +   +        ++ 
Sbjct: 464 VGNAALGKVYAPDPDDWDNKT--YTLETSAAK--YFSLNQSSGELTIRQ---NAPAGSYW 516

Query: 655 LKAVAIDGGTPPQSSTVIVHIK 676
           L+    DG  P   S + VH++
Sbjct: 517 LRVGVSDGVWPDVISGIRVHVR 538



 Score = 83.4 bits (197), Expect = 8e-14
 Identities = 93/352 (26%), Positives = 146/352 (41%), Gaps = 37/352 (10%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ + D ND+ PVF  + YE  V E A  G  V+T+ ATD+D G NA++ Y I       
Sbjct: 111 RVFISDVNDNKPVFAQRLYEVGVDEDADVGLAVVTVSATDEDEGANAKLRYQI------- 163

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                              VF I+   G +     LD E+  RY +LV A+D       R
Sbjct: 164 ------------TSGNKGGVFDIEPEVGTIFVAQPLDYEQQKRYKLLVLASD------GR 205

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD-ADVGANSAIR 188
               A I V +++ ND  P FS   Y  SV E++  +   V+      D A   A+S+  
Sbjct: 206 WEDYAAIVVTVVNKNDEAPVFSMNEYYGSVTEELDGSPVFVLQIDDENDNAPEFASSSHL 265

Query: 189 YAIIGGNTQMQFSIDSL---SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
              +  +  +  SI  +     D  L   + Y  +            G+P+ + +  + +
Sbjct: 266 LPPLPEDVPVGTSIIQVVATDTDSGLNGEILYSILPQSDPHGHFATAGTPALTASVTVHL 325

Query: 246 NIRDVNDNAPRFYTS----LFQESVSENVP-IGYSIVRVQAYDADEGVNAELTYTMTDKD 300
            + D NDN P   T+    L++ S +  V  +  S   +   D D   N    Y      
Sbjct: 326 LLLDTNDNGPELETAYAPVLWENSPAPQVVWLNQSSTLLHVVDRDSPENGPPYYLSLPSL 385

Query: 301 YTGNVDLPITIDPRSGWVYTSGQL-DRETQAKYQLLVTATDGGDPPRSATAT 351
           Y  +VD  +        + T+ ++ DRE Q+++ L V   D GDPP +AT T
Sbjct: 386 Y--SVDFHLQDHGNGSAMLTALRMFDRERQSEFHLPVIMVDSGDPPMTATNT 435



 Score = 65.7 bits (153), Expect = 2e-08
 Identities = 68/253 (26%), Positives = 110/253 (43%), Gaps = 16/253 (6%)

Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738
           D+ND+ P F S      ++E + IGT++ ++ AHD D G N  + Y++   D S   SL 
Sbjct: 1   DVNDNVPFFTSSIYEASVTEGAQIGTSVLQVSAHDKDLGLNGQITYTLLS-DSSGDHSL- 58

Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRA------ASP-----PLWNDVRVEILVTDV 787
            R   +   + T    D E+ R  Y L +++      A P     P  +   V + ++DV
Sbjct: 59  FRIDPELGIIYTEAVFDREA-RSSYLLEVQSEDGQESARPGKNKQPNSDTAYVRVFISDV 117

Query: 788 NDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNET 845
           NDN PV           +D         V A D D     KL+Y+I SGN   +  +   
Sbjct: 118 NDNKPVFAQRLYEVGVDEDADVGLAVVTVSATDEDEGANAKLRYQITSGNKGGVFDIEPE 177

Query: 846 TGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTA 905
            G++ ++  L+    K   + V  +DG  E  A + ++V    +E  + S+      +T 
Sbjct: 178 VGTIFVAQPLDYEQQKRYKLLVLASDGRWEDYAAIVVTVVNKNDEAPVFSMNEYYGSVTE 237

Query: 906 EQFLSPLLGFFID 918
           E   SP+    ID
Sbjct: 238 ELDGSPVFVLQID 250



 Score = 64.9 bits (151), Expect = 3e-08
 Identities = 63/214 (29%), Positives = 91/214 (42%), Gaps = 29/214 (13%)

Query: 1387 QRDAFVMSIQLKSGLLHYSYN-GETMY---LPMATLSDGAWHRIEIKWLGTDISVTVDYG 1442
            Q+ + V+S Q+  GLL   YN G+  Y   LP   LSDG WH +E+   G + ++ +D G
Sbjct: 901  QQSSPVLS-QVIQGLLAVFYNLGDGDYNLTLPHQHLSDGEWHELELDRYGREFTLRLDGG 959

Query: 1443 LRTVLMPMLANKIQGQYIGKILIGGLDTTAG--LLASDVGFFEGCIQDVRIGTAQSLLN- 1499
                   + A++ QGQ   +I++       G    +     F GC++D+R       L+ 
Sbjct: 960  --GGRREVTASRGQGQ---EIVVDPTTVMLGNSFPSGHNHSFLGCMRDLRFNGHSIPLDP 1014

Query: 1500 -------RPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRV------GP 1546
                   +    + V  GC S A C    C P   CV  W    C C  G +      G 
Sbjct: 1015 EQTSDRLQVVAVQGVSPGCSSEA-CRQHQCSPPLVCVDLWRHHECRCPPGHITRETTQGK 1073

Query: 1547 QCV-SACELGPCGAARCVPDQTPKGYSCACEPGY 1579
             C+ + C   PC    CV   +P  YSC C  GY
Sbjct: 1074 VCMYTLCASRPCRHGTCVA-HSPSRYSCHCSEGY 1106



 Score = 52.0 bits (119), Expect = 2e-04
 Identities = 64/254 (25%), Positives = 103/254 (40%), Gaps = 30/254 (11%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + V++ ND +PVF M +Y  SV E    G+ V  L+  D++   NA  E+         L
Sbjct: 214 VTVVNKNDEAPVFSMNEYYGSVTEELD-GSPVFVLQIDDEN--DNAP-EFASSSHLLPPL 269

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ---ASPVS 127
            PED             D     G +G +L            Y++L ++      A+  +
Sbjct: 270 -PEDVPVGTSIIQVVATDTD--SGLNGEIL------------YSILPQSDPHGHFATAGT 314

Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTD----NPVIAKIKATDADVGA 183
             L+++ T+H+ ++D NDN P+  E  Y   + E+         N     +   D D   
Sbjct: 315 PALTASVTVHLLLLDTNDNGPEL-ETAYAPVLWENSPAPQVVWLNQSSTLLHVVDRDSPE 373

Query: 184 NSAIRYAIIGGNTQMQFSI-DSLSGDVSL--VKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240
           N    Y  +     + F + D  +G   L  ++  D E+   + L +   D G P  + T
Sbjct: 374 NGPPYYLSLPSLYSVDFHLQDHGNGSAMLTALRMFDRERQSEFHLPVIMVDSGDPPMTAT 433

Query: 241 TQLLINIRDVNDNA 254
             L I I D NDNA
Sbjct: 434 NTLTITIGDQNDNA 447



 Score = 38.3 bits (85), Expect = 3.0
 Identities = 20/66 (30%), Positives = 26/66 (39%), Gaps = 4/66 (6%)

Query: 1287 DFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSA----PCYNGAECSDLWDTYICDCKEG 1342
            D   + K  DL S    + T+ GC      C+      PC     C   W +Y C C+ G
Sbjct: 832  DVRSNSKLYDLGSPAEASNTVPGCTLIDGHCTDGEPRPPCGLRGHCHSHWGSYSCLCQPG 891

Query: 1343 HTGKDC 1348
             TG  C
Sbjct: 892  FTGPQC 897


>UniRef50_UPI000069E6F7 Cluster: UPI000069E6F7 related cluster; n=1;
           Xenopus tropicalis|Rep: UPI000069E6F7 UniRef100 entry -
           Xenopus tropicalis
          Length = 602

 Score =  188 bits (457), Expect = 3e-45
 Identities = 166/565 (29%), Positives = 259/565 (45%), Gaps = 55/565 (9%)

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
           +V E +P G  +  ++A    EG   E  + ++++D    V     +D  +G V T   L
Sbjct: 9   AVDEGLPPGTLVGDIRA-GLPEGSPGE-GFFLSEEDGESLVLRDFQVDSETGIVSTLQVL 66

Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
           DRE +  Y   V AT  G+                      F     +++++E  PPGT 
Sbjct: 67  DRERREHYSF-VAATLQGE-----VVQVDILVRDVNDHSPTFPVHSLQLQVSELTPPGTS 120

Query: 385 VVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGR----------GLITVAQPLDF- 431
                A D D  E     Y +  G+    F I   +G+          G  +   PLD  
Sbjct: 121 FRLPAAWDPDIGEHGLKGYALLRGSQEAPFIIRYGHGKTHNKRMVEGVGADSTLHPLDLV 180

Query: 432 -------KQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
                  ++   Y L V A D G   R+   +V I + DAN+  PVF+   Y   V+E+A
Sbjct: 181 LIQWLDREELDNYQLEVEAFDGGNPRRTGRLIVDIVVMDANDNPPVFDQLDYKGWVWENA 240

Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
           PIGT+V  V ATD D+G N ++ YSL            +  F ++ ++G I+ ++ LDRE
Sbjct: 241 PIGTSVCTVHATDPDLGSNGEVRYSLR---------FGEGYFTVDEESGEISVSRPLDRE 291

Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN----IMEDALVGT 598
            +S + L V ARDGG      +  + + V+DVNDN P     L T +    + E A  G 
Sbjct: 292 QISIHQLVVQARDGGDQPEVTSILLTVKVLDVNDNSPGIHITLITESGRPEVSEGARTGE 351

Query: 599 SVSQVGATDADVGLNGRIHYELDPKDR-----EEGSFVIDPASGVIR---TNKALDRESV 650
            ++++  +D D+     +  E D + R      EGSF + PA   +     N  LDRE  
Sbjct: 352 YLARIFVSDPDLESEDEVWVEGDTERRLILEGGEGSFSLQPAGPQLYFLCVNAPLDRELK 411

Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF-ESDCLTFYISENSPIGTTIGEI 709
             ++L+ +A D G+PP  S   + + + D+ND PP+F + +     ISE + IGT +  +
Sbjct: 412 DMYELQILAWDTGSPPLQSHKTLLLSVTDLNDQPPMFLQPEGYQATISEATSIGTAVLML 471

Query: 710 RAHDPDE-GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768
           +A D DE GPN+ V YS++   +S+SF LE   G+    +  ++D +         +   
Sbjct: 472 KAQDLDEDGPNSRVTYSLQESQNSSSFILEP--GTGVLSIAQLLDHESAPVLNLVAVATD 529

Query: 769 AASPPLWNDVRVEILVTDVNDNAPV 793
             SPPL +   + I V D NDN P+
Sbjct: 530 HGSPPLSSSCTITITVEDTNDNDPI 554



 Score =  181 bits (441), Expect = 2e-43
 Identities = 158/542 (29%), Positives = 241/542 (44%), Gaps = 45/542 (8%)

Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259
           F +DS +G VS ++ LD E+   Y  V     G         Q+ I +RDVND++P F  
Sbjct: 51  FQVDSETGIVSTLQVLDRERREHYSFVAATLQG------EVVQVDILVRDVNDHSPTFPV 104

Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT------------------DKDY 301
              Q  VSE  P G S     A+D D G +    Y +                   +K  
Sbjct: 105 HSLQLQVSELTPPGTSFRLPAAWDPDIGEHGLKGYALLRGSQEAPFIIRYGHGKTHNKRM 164

Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361
              V    T+ P    +     LDRE    YQL V A DGG+P R+              
Sbjct: 165 VEGVGADSTLHPLD--LVLIQWLDREELDNYQLEVEAFDGGNPRRTGRLIVDIVVMDAND 222

Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419
               F    Y+  + E+ P GT V T+ ATD D   +  + Y +  G   G F++  ++G
Sbjct: 223 NPPVFDQLDYKGWVWENAPIGTSVCTVHATDPDLGSNGEVRYSLRFGE--GYFTVDEESG 280

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTAS 477
              I+V++PLD +Q   + L V A D G + +    ++ + + D N+ +P       T S
Sbjct: 281 E--ISVSRPLDREQISIHQLVVQARDGGDQPEVTSILLTVKVLDVNDNSPGIHITLITES 338

Query: 478 ----VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP---QT 530
               V E A  G  +  +  +D D+    ++     +E     +   +  F + P   Q 
Sbjct: 339 GRPEVSEGARTGEYLARIFVSDPDLESEDEVWVEGDTE-RRLILEGGEGSFSLQPAGPQL 397

Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ-QLYTAN 589
             +  N  LDRE    Y L + A D G P L     + +SV D+ND  P+F Q + Y A 
Sbjct: 398 YFLCVNAPLDRELKDMYELQILAWDTGSPPLQSHKTLLLSVTDLNDQPPMFLQPEGYQAT 457

Query: 590 IMEDALVGTSVSQVGATDADV-GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648
           I E   +GT+V  + A D D  G N R+ Y L  + +   SF+++P +GV+   + LD E
Sbjct: 458 ISEATSIGTAVLMLKAQDLDEDGPNSRVTYSLQ-ESQNSSSFILEPGTGVLSIAQLLDHE 516

Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
           S    +L AVA D G+PP SS+  + I +ED ND+ P+F        + E++ +G    +
Sbjct: 517 SAPVLNLVAVATDHGSPPLSSSCTITITVEDTNDNDPIFLQQFYNVSLQEHTVLGHCFLQ 576

Query: 709 IR 710
           +R
Sbjct: 577 LR 578



 Score =  181 bits (441), Expect = 2e-43
 Identities = 156/547 (28%), Positives = 248/547 (45%), Gaps = 65/547 (11%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F++D  +G + T   LDRE+   Y+  V AT Q   V         + + + D ND+ P 
Sbjct: 51  FQVDSETGIVSTLQVLDRERREHYS-FVAATLQGEVVQ--------VDILVRDVNDHSPT 101

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKAT-DADVGANSAIRYAIIGGNTQMQFSIDSLSG- 207
           F   +  + V E   +T      ++ A  D D+G +    YA++ G+ +  F I    G 
Sbjct: 102 FPVHSLQLQVSE---LTPPGTSFRLPAAWDPDIGEHGLKGYALLRGSQEAPFIIRYGHGK 158

Query: 208 -------------------DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
                              D+ L++ LD E++ +Y+L + A DGG+P R+    + I + 
Sbjct: 159 THNKRMVEGVGADSTLHPLDLVLIQWLDREELDNYQLEVEAFDGGNPRRTGRLIVDIVVM 218

Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT-DKDYTGNVDL 307
           D NDN P F    ++  V EN PIG S+  V A D D G N E+ Y++   + Y      
Sbjct: 219 DANDNPPVFDQLDYKGWVWENAPIGTSVCTVHATDPDLGSNGEVRYSLRFGEGY------ 272

Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA----TATXXXXXXXXXXXX 363
             T+D  SG +  S  LDRE  + +QL+V A DGGD P       T              
Sbjct: 273 -FTVDEESGEISVSRPLDREQISIHQLVVQARDGGDQPEVTSILLTVKVLDVNDNSPGIH 331

Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTR--------GRFSIT 415
              +      E++E    G  +  +  +D D ++     + G   R        G FS+ 
Sbjct: 332 ITLITESGRPEVSEGARTGEYLARIFVSDPDLESEDEVWVEGDTERRLILEGGEGSFSLQ 391

Query: 416 SQNGR-GLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVF-EN 471
               +   + V  PLD + +  Y L + A D+G         + +++TD N+  P+F + 
Sbjct: 392 PAGPQLYFLCVNAPLDRELKDMYELQILAWDTGSPPLQSHKTLLLSVTDLNDQPPMFLQP 451

Query: 472 APYTASVFEDAPIGTTVLVVSATDSDV-GINAQITYSLSSEISNEAVAHHDQQFVINPQT 530
             Y A++ E   IGT VL++ A D D  G N+++TYSL         + +   F++ P T
Sbjct: 452 EGYQATISEATSIGTAVLMLKAQDLDEDGPNSRVTYSLQE-------SQNSSSFILEPGT 504

Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590
           G ++  +LLD E+     L   A D G P LS +  + I+V D NDN+P+F QQ Y  ++
Sbjct: 505 GVLSIAQLLDHESAPVLNLVAVATDHGSPPLSSSCTITITVEDTNDNDPIFLQQFYNVSL 564

Query: 591 MEDALVG 597
            E  ++G
Sbjct: 565 QEHTVLG 571



 Score =  164 bits (398), Expect = 4e-38
 Identities = 157/552 (28%), Positives = 248/552 (44%), Gaps = 50/552 (9%)

Query: 371 YEVELAEDE--PPGTPVVTLTA--TDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
           Y + LA DE  PPGT V  + A   +             G +         +  G+++  
Sbjct: 4   YNLSLAVDEGLPPGTLVGDIRAGLPEGSPGEGFFLSEEDGESLVLRDFQVDSETGIVSTL 63

Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486
           Q LD ++ R +   V+AT  G   +   V I + D N+++P F        V E  P GT
Sbjct: 64  QVLD-RERREHYSFVAATLQG---EVVQVDILVRDVNDHSPTFPVHSLQLQVSELTPPGT 119

Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEA-----VAH---HDQQFVINPQTGA------ 532
           +  + +A D D+G +    Y+L    S EA       H   H+++ V      +      
Sbjct: 120 SFRLPAAWDPDIGEHGLKGYALLRG-SQEAPFIIRYGHGKTHNKRMVEGVGADSTLHPLD 178

Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592
           +   + LDRE +  Y L V A DGG P  +    V+I V+D NDN PVF Q  Y   + E
Sbjct: 179 LVLIQWLDREELDNYQLEVEAFDGGNPRRTGRLIVDIVVMDANDNPPVFDQLDYKGWVWE 238

Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652
           +A +GTSV  V ATD D+G NG + Y L      EG F +D  SG I  ++ LDRE ++ 
Sbjct: 239 NAPIGTSVCTVHATDPDLGSNGEVRYSL---RFGEGYFTVDEESGEISVSRPLDREQISI 295

Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF----YISENSPIGTTIGE 708
           H L   A DGG  P+ +++++ +K+ D+ND+ P      +T      +SE +  G  +  
Sbjct: 296 HQLVVQARDGGDQPEVTSILLTVKVLDVNDNSPGIHITLITESGRPEVSEGARTGEYLAR 355

Query: 709 IRAHDPD-EGPNAV-------VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760
           I   DPD E  + V           ++GG+   SFSL+   G     L     LD E  +
Sbjct: 356 IFVSDPDLESEDEVWVEGDTERRLILEGGE--GSFSLQP-AGPQLYFLCVNAPLDREL-K 411

Query: 761 KKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRV 816
             YEL I A    SPPL +   + + VTD+ND  P+    +       +   +G     +
Sbjct: 412 DMYELQILAWDTGSPPLQSHKTLLLSVTDLNDQPPMFLQPEGYQATISEATSIGTAVLML 471

Query: 817 PAYDAD---VTDKLQYRILSGNNANLILLNETTGSMTLSPQL-NTNVPKLATMEVSVTDG 872
            A D D      ++ Y +    N++  +L   TG ++++  L + + P L  + V+   G
Sbjct: 472 KAQDLDEDGPNSRVTYSLQESQNSSSFILEPGTGVLSIAQLLDHESAPVLNLVAVATDHG 531

Query: 873 VNEIKAMMQLSV 884
              + +   +++
Sbjct: 532 SPPLSSSCTITI 543



 Score =  127 bits (306), Expect = 5e-27
 Identities = 104/383 (27%), Positives = 172/383 (44%), Gaps = 47/383 (12%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V+D ND+ PVF+   Y+  V E A  GT+V T+ ATD D+G N EV Y++        
Sbjct: 215 IVVMDANDNPPVFDQLDYKGWVWENAPIGTSVCTVHATDPDLGSNGEVRYSLRF------ 268

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                           +  F +D  SG +     LDRE+++ + ++V+A D         
Sbjct: 269 ---------------GEGYFTVDEESGEISVSRPLDREQISIHQLVVQARDGGDQPE--- 310

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS--VTDNPVIAKIKATDADVGANSAIR 188
            ++  + V ++D NDN P       T S   ++S        +A+I  +D D+ +   + 
Sbjct: 311 VTSILLTVKVLDVNDNSPGIHITLITESGRPEVSEGARTGEYLARIFVSDPDLESEDEV- 369

Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKT------------LDYEQVRSYRLVIRAQDGGSPS 236
              + G+T+ +  ++   G  SL               LD E    Y L I A D GSP 
Sbjct: 370 --WVEGDTERRLILEGGEGSFSLQPAGPQLYFLCVNAPLDRELKDMYELQILAWDTGSPP 427

Query: 237 RSNTTQLLINIRDVNDNAPRF-YTSLFQESVSENVPIGYSIVRVQAYDADE-GVNAELTY 294
             +   LL+++ D+ND  P F     +Q ++SE   IG +++ ++A D DE G N+ +TY
Sbjct: 428 LQSHKTLLLSVTDLNDQPPMFLQPEGYQATISEATSIGTAVLMLKAQDLDEDGPNSRVTY 487

Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354
           ++ +   + +      ++P +G +  +  LD E+     L+  ATD G PP S++ T   
Sbjct: 488 SLQESQNSSS----FILEPGTGVLSIAQLLDHESAPVLNLVAVATDHGSPPLSSSCTITI 543

Query: 355 XXXXXXXXXXXFMPGQYEVELAE 377
                      F+   Y V L E
Sbjct: 544 TVEDTNDNDPIFLQQFYNVSLQE 566



 Score = 93.1 bits (221), Expect = 1e-16
 Identities = 76/275 (27%), Positives = 123/275 (44%), Gaps = 19/275 (6%)

Query: 11  INVLDCNDHSPVFEMQQYEAS----VREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           + VLD ND+SP   +     S    V EGA +G  +  +  +D D+   +E E  +E  T
Sbjct: 318 VKVLDVNDNSPGIHITLITESGRPEVSEGARTGEYLARIFVSDPDL--ESEDEVWVEGDT 375

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
              L  E             Q  F        L   A LDRE    Y + + A D  SP 
Sbjct: 376 ERRLILEGGEGSFSLQPAGPQLYF--------LCVNAPLDRELKDMYELQILAWDTGSPP 427

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
              L S  T+ +++ D ND  P F + + Y  ++ E  S+    ++ K +  D D G NS
Sbjct: 428 ---LQSHKTLLLSVTDLNDQPPMFLQPEGYQATISEATSIGTAVLMLKAQDLDED-GPNS 483

Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
            + Y++        F ++  +G +S+ + LD+E      LV  A D GSP  S++  + I
Sbjct: 484 RVTYSLQESQNSSSFILEPGTGVLSIAQLLDHESAPVLNLVAVATDHGSPPLSSSCTITI 543

Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQ 280
            + D NDN P F    +  S+ E+  +G+  ++++
Sbjct: 544 TVEDTNDNDPIFLQQFYNVSLQEHTVLGHCFLQLR 578


>UniRef50_A7S9Y2 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 459

 Score =  187 bits (456), Expect = 3e-45
 Identities = 153/489 (31%), Positives = 235/489 (48%), Gaps = 38/489 (7%)

Query: 254 APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313
           +P F  + F  +++EN PIG ++++V A D D      L+Y+++     G+      I  
Sbjct: 1   SPVFSGTPFSATLTENDPIGTTVLKVIAIDEDSADT--LSYSLS-----GSNSAHFAIGS 53

Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373
            +G + T+  LDRET   Y L V+ +DG      A +               F    Y  
Sbjct: 54  STGVITTAQLLDRETVNSYSLTVSVSDGTATVNQALSVTINDANDAPL----FTNAPYNA 109

Query: 374 ELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ 433
            + E+   G+ V T++ATDAD D  + Y I G  +  +FSI S +G  L+T+A  +DF+ 
Sbjct: 110 TVNENAGSGS-VYTVSATDADSDV-IAYSIYGHGS-DKFSIHSSSG--LVTLASAVDFET 164

Query: 434 ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
           +  +VLTV A D+ G   T  + +++ + N+ +P F   PY+ S+ E    GTTV    A
Sbjct: 165 KSSFVLTVQAADTNGAIATTSLYVDVVNQND-SPAFMGTPYSTSIIESVSFGTTVFRAQA 223

Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553
            D D      ++YSLS   +N A     + F I+P +G ++    LD E  S Y+LTV  
Sbjct: 224 VDEDTA--DTLSYSLSG--TNNAHFAIGELFSIHPTSGVVSVTSALDAEVTSLYVLTVRV 279

Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613
            DG      +T+ + ++V+DVND  P F    Y A++ E    GT V  + ATD D    
Sbjct: 280 SDG--KGGVNTSSLSVTVIDVND-RPAFVGAPYAASVSERLPSGTGVVTLIATDQD---G 333

Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673
             + Y +       G F I P++G+I+T + LD ESV ++ L A   DG     + T  V
Sbjct: 334 DSLTYSI--SGTNHGHFSISPSTGLIQTAQILDYESVNSYTLTASVTDGSV---TVTTSV 388

Query: 674 HIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN 733
            I + + ND PP   S      I+EN    + I +I   D D      + YS+  G  S 
Sbjct: 389 TISVTNTND-PPTLSSSYYNVSINENDAALSVI-DITGSDSD---GDTLTYSLT-GTGSG 442

Query: 734 SFSLETRQG 742
            FS+ +  G
Sbjct: 443 DFSMNSATG 451



 Score =  170 bits (413), Expect = 5e-40
 Identities = 151/502 (30%), Positives = 228/502 (45%), Gaps = 48/502 (9%)

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
           P FS   ++ ++ E+  +     + K+ A D D  +   + Y++ G N+   F+I S +G
Sbjct: 2   PVFSGTPFSATLTENDPI--GTTVLKVIAIDED--SADTLSYSLSGSNSA-HFAIGSSTG 56

Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
            ++  + LD E V SY L +   DG   + +    L + I D ND AP F  + +  +V+
Sbjct: 57  VITTAQLLDRETVNSYSLTVSVSDG---TATVNQALSVTINDAND-APLFTNAPYNATVN 112

Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
           EN   G S+  V A DAD  V A   Y        G+     +I   SG V  +  +D E
Sbjct: 113 ENAGSG-SVYTVSATDADSDVIAYSIY--------GHGSDKFSIHSSSGLVTLASAVDFE 163

Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387
           T++ + L V A D      +   T              FM   Y   + E    GT V  
Sbjct: 164 TKSSFVLTVQAADTNG---AIATTSLYVDVVNQNDSPAFMGTPYSTSIIESVSFGTTVFR 220

Query: 388 LTATDADEDNRLHYEITGGNTRGRFSI----TSQNGRGLITVAQPLDFKQERRYVLTVSA 443
             A D D  + L Y ++G N    F+I    +     G+++V   LD +    YVLTV  
Sbjct: 221 AQAVDEDTADTLSYSLSGTN-NAHFAIGELFSIHPTSGVVSVTSALDAEVTSLYVLTVRV 279

Query: 444 TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503
           +D  G  +T+ + + + D N+  P F  APY ASV E  P GT V+ + ATD D      
Sbjct: 280 SDGKGGVNTSSLSVTVIDVND-RPAFVGAPYAASVSERLPSGTGVVTLIATDQD---GDS 335

Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD 563
           +TYS+S         +H   F I+P TG I T ++LD E+++ Y LT +  DG   S++ 
Sbjct: 336 LTYSISG-------TNHG-HFSISPSTGLIQTAQILDYESVNSYTLTASVTDG---SVTV 384

Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK 623
           TT V ISV + ND  P      Y  +I E+     SV  +  +D+D      + Y L   
Sbjct: 385 TTSVTISVTNTND-PPTLSSSYYNVSINEND-AALSVIDITGSDSD---GDTLTYSL--T 437

Query: 624 DREEGSFVIDPASGVIRTNKAL 645
               G F ++ A+G+I    AL
Sbjct: 438 GTGSGDFSMNSATGLITLATAL 459



 Score =  124 bits (300), Expect = 3e-26
 Identities = 135/458 (29%), Positives = 208/458 (45%), Gaps = 33/458 (7%)

Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525
           +PVF   P++A++ E+ PIGTTVL V A D D      ++YSLS   SN A       F 
Sbjct: 1   SPVFSGTPFSATLTENDPIGTTVLKVIAIDEDSADT--LSYSLSG--SNSA------HFA 50

Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585
           I   TG ITT +LLDRET++ Y LTV+  DG   + +    + +++ D ND  P+F    
Sbjct: 51  IGSSTGVITTAQLLDRETVNSYSLTVSVSDG---TATVNQALSVTINDAND-APLFTNAP 106

Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645
           Y A + E+A  G SV  V ATDAD  +   I Y +     ++  F I  +SG++    A+
Sbjct: 107 YNATVNENAGSG-SVYTVSATDADSDV---IAYSIYGHGSDK--FSIHSSSGLVTLASAV 160

Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
           D E+ ++  L   A D  T    +T  +++ + + NDS P F     +  I E+   GTT
Sbjct: 161 DFETKSSFVLTVQAAD--TNGAIATTSLYVDVVNQNDS-PAFMGTPYSTSIIESVSFGTT 217

Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765
           +   RA   DE     + YS+ G ++++    E       + +V++           Y L
Sbjct: 218 V--FRAQAVDEDTADTLSYSLSGTNNAHFAIGELFSIHPTSGVVSVTSALDAEVTSLYVL 275

Query: 766 VIRAASPPLW-NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVT 824
            +R +      N   + + V DVND  P          +  +  P G  G V     D  
Sbjct: 276 TVRVSDGKGGVNTSSLSVTVIDVNDR-PAFVGAPYA-ASVSERLPSGT-GVVTLIATDQD 332

Query: 825 -DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLS 883
            D L Y I SG N     ++ +TG +  +  L+       T+  SVTDG   +   + +S
Sbjct: 333 GDSLTYSI-SGTNHGHFSISPSTGLIQTAQILDYESVNSYTLTASVTDGSVTVTTSVTIS 391

Query: 884 VRLITEEMLLNS--ITVRLNDMTAEQFLSPLLGFFIDG 919
           V    +   L+S    V +N+  A   +  + G   DG
Sbjct: 392 VTNTNDPPTLSSSYYNVSINENDAALSVIDITGSDSDG 429



 Score = 94.7 bits (225), Expect = 3e-17
 Identities = 87/287 (30%), Positives = 135/287 (47%), Gaps = 37/287 (12%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           ++V++ ND SP F    Y  S+ E  S GTTV   +A D+D              TADTL
Sbjct: 188 VDVVNQND-SPAFMGTPYSTSIIESVSFGTTVFRAQAVDED--------------TADTL 232

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           +   +          + ++F I   SG +   ++LD E  + Y + V+ +D    V+   
Sbjct: 233 SY--SLSGTNNAHFAIGELFSIHPTSGVVSVTSALDAEVTSLYVLTVRVSDGKGGVN--- 287

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
             T+++ V +ID ND  P F    Y  SV E +  +   V+  I ATD D     ++ Y+
Sbjct: 288 --TSSLSVTVIDVNDR-PAFVGAPYAASVSERLP-SGTGVVTLI-ATDQD---GDSLTYS 339

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
           I G N    FSI   +G +   + LDYE V SY L     DG   S + TT + I++ + 
Sbjct: 340 ISGTN-HGHFSISPSTGLIQTAQILDYESVNSYTLTASVTDG---SVTVTTSVTISVTNT 395

Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297
           ND  P   +S +  S++EN     S++ +   D+D      LTY++T
Sbjct: 396 ND-PPTLSSSYYNVSINEN-DAALSVIDITGSDSD---GDTLTYSLT 437


>UniRef50_Q96JP9 Cluster: Protocadherin-21; n=30; Euteleostomi|Rep:
           Protocadherin-21 - Homo sapiens (Human)
          Length = 858

 Score =  187 bits (455), Expect = 4e-45
 Identities = 180/605 (29%), Positives = 259/605 (42%), Gaps = 53/605 (8%)

Query: 167 DNPVIAKIKATDADVGANSAIRYAI-IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRL 225
           D PV + +   +        I Y I    +T+  FS+D   G+++LV+ LD E+      
Sbjct: 46  DTPVGSHVYTLNGTDPEGDPISYHISFDPSTRSVFSVDPTFGNITLVEELDREREDEIEA 105

Query: 226 VIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD 285
           +I   DG         +++I + D ND APRF    +   V E++P G  I +V A D D
Sbjct: 106 IISISDG---LNLVAEKVVILVTDANDEAPRFIQEPYVALVPEDIPAGSIIFKVHAVDRD 162

Query: 286 EGVNAELTYTMTDKDYTGNVDLPITIDPRSG--WVYTSGQLDRETQAKYQLLVTATDGG- 342
            G    +TY      +  N+  P  +D  SG   +     LD E    + + V A DGG 
Sbjct: 163 TGSGGSVTY------FLQNLHSPFAVDRHSGVLRLQAGATLDYERSRTHYITVVAKDGGG 216

Query: 343 -----DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--E 395
                D   SAT T              F+   Y   + ED  PG+ V+ + A D D  +
Sbjct: 217 RLHGADVVFSATTTVTVNVEDVQDMAPVFVGTPYYGYVYEDTLPGSEVLKVVAMDGDRGK 276

Query: 396 DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD-----SGGRS 450
            NR+ Y +  GN  G F I   +  G I++ Q     Q   Y L V  T+     S    
Sbjct: 277 PNRILYSLVNGND-GAFEINETS--GAISITQSPAQLQREVYELHVQVTEMSPAGSPAAQ 333

Query: 451 DTAMVQINITDANNYAPVF--ENAP---YTASVFEDAPIGTTV--LVVSATDSDVGINAQ 503
            T  V I I D NN+ P F  E+ P   +  S+ E  P G  +  L ++  DSD G NA+
Sbjct: 334 ATVPVTIRIVDLNNHPPTFYGESGPQNRFELSMNEHPPQGEILRGLKITVNDSDQGANAK 393

Query: 504 ITYSLSSEISNEAVAHHDQQFVIN-PQTGAITTNK-LLDRETMSGYLLTVTARDGGVP-S 560
               L   +    +     Q V+N  Q   I  N   +D E        + A +   P  
Sbjct: 394 FNLQL---VGPRGIFRVVPQTVLNEAQVTIIVENSAAIDFEKSKVLTFKLLAVEVNTPEK 450

Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620
            S T DV I ++D NDN P F    Y A I E+A  G+SV  V A D D G  G + Y  
Sbjct: 451 FSSTADVVIQLLDTNDNVPKFDSLYYVARIPENAPGGSSVVAVTAVDPDTGPWGEVKYST 510

Query: 621 DPKDREEGSFVIDPASGVIRTN--KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678
                +   F+I P++G+I T    +LD E+ A ++    A D     + S   V I + 
Sbjct: 511 YGTGAD--LFLIHPSTGLIYTQPWASLDAEATARYNFYVKAED--MEGKYSVAEVFITLL 566

Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSL 737
           D+ND PP F          +   +GT + +I A D D E PN +V YSI   + +N F +
Sbjct: 567 DVNDHPPQFGKSVQ----KKTMVLGTPV-KIEAIDEDAEEPNNLVDYSITHAEPANVFDI 621

Query: 738 ETRQG 742
            +  G
Sbjct: 622 NSHTG 626



 Score =  159 bits (387), Expect = 8e-37
 Identities = 150/504 (29%), Positives = 228/504 (45%), Gaps = 40/504 (7%)

Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434
           L ED P G+ V TL  TD + D   ++     +TR  FS+    G   IT+ + LD ++E
Sbjct: 43  LPEDTPVGSHVYTLNGTDPEGDPISYHISFDPSTRSVFSVDPTFGN--ITLVEELDRERE 100

Query: 435 RRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494
                 +S +D G       V I +TDAN+ AP F   PY A V ED P G+ +  V A 
Sbjct: 101 DEIEAIISISD-GLNLVAEKVVILVTDANDEAPRFIQEPYVALVPEDIPAGSIIFKVHAV 159

Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554
           D D G    +TY L +  S  AV  H    V+  Q GA      LD E    + +TV A+
Sbjct: 160 DRDTGSGGSVTYFLQNLHSPFAVDRHSG--VLRLQAGA-----TLDYERSRTHYITVVAK 212

Query: 555 DGG------VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
           DGG          S TT V ++V DV D  PVF    Y   + ED L G+ V +V A D 
Sbjct: 213 DGGGRLHGADVVFSATTTVTVNVEDVQDMAPVFVGTPYYGYVYEDTLPGSEVLKVVAMDG 272

Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA---LDRESVATHDLKAVAIDGGTP 665
           D G   RI Y L   +  +G+F I+  SG I   ++   L RE    H         G+P
Sbjct: 273 DRGKPNRILYSL--VNGNDGAFEINETSGAISITQSPAQLQREVYELHVQVTEMSPAGSP 330

Query: 666 PQSSTVIVHIKIEDINDSPPVFESDC-----LTFYISENSPIGTTIG--EIRAHDPDEGP 718
              +TV V I+I D+N+ PP F  +          ++E+ P G  +   +I  +D D+G 
Sbjct: 331 AAQATVPVTIRIVDLNNHPPTFYGESGPQNRFELSMNEHPPQGEILRGLKITVNDSDQGA 390

Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD----LDYESPR-KKYELV-IRAASP 772
           NA  +  + G      F +  +   ++A++  +V+    +D+E  +   ++L+ +   +P
Sbjct: 391 NAKFNLQLVG--PRGIFRVVPQTVLNEAQVTIIVENSAAIDFEKSKVLTFKLLAVEVNTP 448

Query: 773 PLWNDVR-VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQY 829
             ++    V I + D NDN P       +    ++         V A D D     +++Y
Sbjct: 449 EKFSSTADVVIQLLDTNDNVPKFDSLYYVARIPENAPGGSSVVAVTAVDPDTGPWGEVKY 508

Query: 830 RILSGNNANLILLNETTGSMTLSP 853
               G  A+L L++ +TG +   P
Sbjct: 509 STY-GTGADLFLIHPSTGLIYTQP 531



 Score =  157 bits (381), Expect = 4e-36
 Identities = 172/679 (25%), Positives = 295/679 (43%), Gaps = 77/679 (11%)

Query: 66  TADTLNPE-DAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS 124
           T +  +PE D            + VF +D   G +     LDRE+      ++  +D  +
Sbjct: 55  TLNGTDPEGDPISYHISFDPSTRSVFSVDPTFGNITLVEELDREREDEIEAIISISDGLN 114

Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184
            V+++      + + + D ND  P+F ++ Y   V EDI      +I K+ A D D G+ 
Sbjct: 115 LVAEK------VVILVTDANDEAPRFIQEPYVALVPEDIPA--GSIIFKVHAVDRDTGSG 166

Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSR----- 237
            ++ Y +   N    F++D  SG + L    TLDYE+ R++ + + A+DGG         
Sbjct: 167 GSVTYFL--QNLHSPFAVDRHSGVLRLQAGATLDYERSRTHYITVVAKDGGGRLHGADVV 224

Query: 238 -SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
            S TT + +N+ DV D AP F  + +   V E+   G  +++V A D D G    + Y++
Sbjct: 225 FSATTTVTVNVEDVQDMAPVFVGTPYYGYVYEDTLPGSEVLKVVAMDGDRGKPNRILYSL 284

Query: 297 TDKDYTGNVDLPITIDPRSGWV---YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353
            +    GN D    I+  SG +    +  QL RE    +  +   +  G P   AT    
Sbjct: 285 VN----GN-DGAFEINETSGAISITQSPAQLQREVYELHVQVTEMSPAGSPAAQATVPVT 339

Query: 354 XXXXXXXXXXXXFM-----PGQYEVELAEDEPPGTPV--VTLTATDADEDNRLHYEITGG 406
                       F        ++E+ + E  P G  +  + +T  D+D+     + +   
Sbjct: 340 IRIVDLNNHPPTFYGESGPQNRFELSMNEHPPQGEILRGLKITVNDSDQGANAKFNLQLV 399

Query: 407 NTRGRFSITSQN--GRGLITV----AQPLDFKQERRY---VLTVSATDSGGRSDTAMVQI 457
             RG F +  Q       +T+    +  +DF++ +     +L V        S TA V I
Sbjct: 400 GPRGIFRVVPQTVLNEAQVTIIVENSAAIDFEKSKVLTFKLLAVEVNTPEKFSSTADVVI 459

Query: 458 NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517
            + D N+  P F++  Y A + E+AP G++V+ V+A D D G   ++ YS     ++   
Sbjct: 460 QLLDTNDNVPKFDSLYYVARIPENAPGGSSVVAVTAVDPDTGPWGEVKYSTYGTGAD--- 516

Query: 518 AHHDQQFVINPQTGAITTN--KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575
                 F+I+P TG I T     LD E  + Y   V A D  +       +V I+++DVN
Sbjct: 517 -----LFLIHPSTGLIYTQPWASLDAEATARYNFYVKAED--MEGKYSVAEVFITLLDVN 569

Query: 576 DNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV-GLNGRIHYELDPKDREEGSFVIDP 634
           D+ P F + +    +    ++GT V ++ A D D    N  + Y +   +     F I+ 
Sbjct: 570 DHPPQFGKSVQKKTM----VLGTPV-KIEAIDEDAEEPNNLVDYSITHAE-PANVFDINS 623

Query: 635 ASGVIRTNKALDRESVATHD----------LKAVAIDGGTPPQSSTVIVHIKIEDINDSP 684
            +G I    ++ R   A H+          L+  A D G+P  S+T ++ I   DI D+ 
Sbjct: 624 HTGEIWLKNSI-RSLDALHNITPGRDCLWSLEVQAKDRGSPSFSTTALLKI---DITDAE 679

Query: 685 PVFESDCLTFYI-SENSPI 702
            +  S    F I ++++P+
Sbjct: 680 TLSRSPMAAFLIQTKDNPM 698



 Score =  126 bits (304), Expect = 9e-27
 Identities = 141/584 (24%), Positives = 236/584 (40%), Gaps = 49/584 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V D ND +P F  + Y A V E   +G+ +  + A D+D G    V Y ++       
Sbjct: 122 ILVTDANDEAPRFIQEPYVALVPEDIPAGSIIFKVHAVDRDTGSGGSVTYFLQ------- 174

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR--ASLDREKVARYTVLVKATDQASPVSD 128
                          +   F +D  SG L  +  A+LD E+   + + V A D    +  
Sbjct: 175 --------------NLHSPFAVDRHSGVLRLQAGATLDYERSRTHYITVVAKDGGGRLHG 220

Query: 129 R---LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
                S+T T+ VN+ D  D  P F    Y   V ED        + K+ A D D G  +
Sbjct: 221 ADVVFSATTTVTVNVEDVQDMAPVFVGTPYYGYVYED--TLPGSEVLKVVAMDGDRGKPN 278

Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD---GGSPSRSNTTQ 242
            I Y+++ GN    F I+  SG +S+ ++    Q   Y L ++  +    GSP+   T  
Sbjct: 279 RILYSLVNGN-DGAFEINETSGAISITQSPAQLQREVYELHVQVTEMSPAGSPAAQATVP 337

Query: 243 LLINIRDVNDNAPRFY-----TSLFQESVSENVPIGYSI--VRVQAYDADEGVNAELTYT 295
           + I I D+N++ P FY      + F+ S++E+ P G  +  +++   D+D+G NA+    
Sbjct: 338 VTIRIVDLNNHPPTFYGESGPQNRFELSMNEHPPQGEILRGLKITVNDSDQGANAKFNLQ 397

Query: 296 MTDKDYTGNVDLPITIDPRSG---WVYTSGQLDRETQAKYQLLVTATDGGDPPR-SATAT 351
           +        V +P T+   +     V  S  +D E        + A +   P + S+TA 
Sbjct: 398 LVGPRGIFRV-VPQTVLNEAQVTIIVENSAAIDFEKSKVLTFKLLAVEVNTPEKFSSTAD 456

Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTR 409
                         F    Y   + E+ P G+ VV +TA D D      + Y  T G   
Sbjct: 457 VVIQLLDTNDNVPKFDSLYYVARIPENAPGGSSVVAVTAVDPDTGPWGEVKYS-TYGTGA 515

Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVF 469
             F I    G         LD +   RY   V A D  G+   A V I + D N++ P F
Sbjct: 516 DLFLIHPSTGLIYTQPWASLDAEATARYNFYVKAEDMEGKYSVAEVFITLLDVNDHPPQF 575

Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
             +    ++    P+    +   A + +  ++  IT++  + + +  +  H  +  +   
Sbjct: 576 GKSVQKKTMVLGTPVKIEAIDEDAEEPNNLVDYSITHAEPANVFD--INSHTGEIWLKNS 633

Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
             ++     +       + L V A+D G PS S T  ++I + D
Sbjct: 634 IRSLDALHNITPGRDCLWSLEVQAKDRGSPSFSTTALLKIDITD 677



 Score =  111 bits (267), Expect = 3e-22
 Identities = 99/331 (29%), Positives = 156/331 (47%), Gaps = 37/331 (11%)

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
           S+ ED P+G+ V  ++ TD +      I+Y +S + S  +V      F ++P  G IT  
Sbjct: 42  SLPEDTPVGSHVYTLNGTDPE---GDPISYHISFDPSTRSV------FSVDPTFGNITLV 92

Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
           + LDRE        ++  D G+  +++   V I V D ND  P F Q+ Y A + ED   
Sbjct: 93  EELDREREDEIEAIISISD-GLNLVAE--KVVILVTDANDEAPRFIQEPYVALVPEDIPA 149

Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR--TNKALDRESVATHD 654
           G+ + +V A D D G  G + Y L         F +D  SGV+R      LD E   TH 
Sbjct: 150 GSIIFKVHAVDRDTGSGGSVTYFL---QNLHSPFAVDRHSGVLRLQAGATLDYERSRTHY 206

Query: 655 LKAVAIDGGTPPQ------SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
           +  VA DGG          S+T  V + +ED+ D  PVF       Y+ E++  G+ + +
Sbjct: 207 ITVVAKDGGGRLHGADVVFSATTTVTVNVEDVQDMAPVFVGTPYYGYVYEDTLPGSEVLK 266

Query: 709 IRAHDPDEG-PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
           + A D D G PN ++ YS+  G+D  +F +    G+     +++     +  R+ YEL +
Sbjct: 267 VVAMDGDRGKPNRIL-YSLVNGND-GAFEINETSGA-----ISITQSPAQLQREVYELHV 319

Query: 768 R------AASPPLWNDVRVEILVTDVNDNAP 792
           +      A SP     V V I + D+N++ P
Sbjct: 320 QVTEMSPAGSPAAQATVPVTIRIVDLNNHPP 350


>UniRef50_UPI0000660953 Cluster: Protocadherin-12 precursor
           (Vascular cadherin-2) (Vascular endothelial cadherin-2)
           (VE-cadherin-2) (VE-cad-2).; n=1; Takifugu rubripes|Rep:
           Protocadherin-12 precursor (Vascular cadherin-2)
           (Vascular endothelial cadherin-2) (VE-cadherin-2)
           (VE-cad-2). - Takifugu rubripes
          Length = 1134

 Score =  186 bits (454), Expect = 6e-45
 Identities = 143/489 (29%), Positives = 226/489 (46%), Gaps = 29/489 (5%)

Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
           N  ++ + + D ND++P+F  +     +SE   +   I   +A D D G N   TY+++ 
Sbjct: 88  NCLRVRVEVMDQNDHSPQFPNAEQDVEISEIAGLRMRIPLERAVDPDAGPNGLQTYSLSV 147

Query: 299 KDYTGNVDLPITIDP---RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355
             Y     L +T+ P   +   +    +LDRE Q    L + A D GDPPRS +      
Sbjct: 148 NRYFA---LDVTVGPEGTKQAELVIIRELDREVQDSVDLSLVAWDKGDPPRSGSTLIHVR 204

Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI---TGGNTRG 410
                     F      VEL E+   GT +++L ATD D+  +  + Y +   T    + 
Sbjct: 205 IQDSNDNSPTFEDSAPTVELPENTARGTTIISLKATDPDQGVNGEVVYSLSKHTQPEVQR 264

Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPV 468
             ++  Q     +++  PLD++ +  Y + V A D G  +  A  +++I   D N+ AP 
Sbjct: 265 LIAVDPQTAA--VSLKAPLDYEVQTSYEVVVEARDRGPNAIPAYCKLHIKLLDVNDNAPR 322

Query: 469 ----FENAPYTA-SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523
               ++ + +   +V E AP  T + +V+  D+D G N ++   +       ++ H    
Sbjct: 323 ILADWDRSSFPGPTVLEGAPKDTFLSLVTVLDADSGQNGKVKAQILEGSGPFSLKH---- 378

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583
             +      I TN  LDRE ++ Y LT+ A+D G P LS    + + VVD NDN PVF  
Sbjct: 379 --MQGGNYKIVTNGTLDREQVTWYNLTLLAQDYGDPPLSSVKHMSVQVVDENDNAPVFST 436

Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE--EGSFVIDPASGVIRT 641
            +Y A+  E    G  + +V A D D+ L+GR+ Y +        +  F I   SGVIR 
Sbjct: 437 NIYKASFEETNRTGYQMLKVEAHDVDLDLSGRVSYFIRNVTGADVDAYFSIHQTSGVIRA 496

Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF-ESDCLTFYISENS 700
              LD E   +H     AID G PP SS+  V I+++D+ND+ PV  E        S + 
Sbjct: 497 QHRLDYEESRSHSFIVEAIDQGHPPLSSSATVQIQVQDVNDNYPVIKEPKPRKGVASLSV 556

Query: 701 PIGTTIGEI 709
           P+    GEI
Sbjct: 557 PVNADKGEI 565



 Score =  182 bits (442), Expect = 2e-43
 Identities = 149/511 (29%), Positives = 225/511 (44%), Gaps = 29/511 (5%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F +  R G L T+  LDRE++ R + L +             +   + V ++D ND+ PQ
Sbjct: 46  FSVGARDGVLATQGRLDREELCRGSDLCEVAFSVLYRKSGAMNCLRVRVEVMDQNDHSPQ 105

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG-- 207
           F      V + E   +     I   +A D D G N    Y++   +    F++D   G  
Sbjct: 106 FPNAEQDVEISEIAGLRMR--IPLERAVDPDAGPNGLQTYSL---SVNRYFALDVTVGPE 160

Query: 208 -----DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLF 262
                ++ +++ LD E   S  L + A D G P RS +T + + I+D NDN+P F  S  
Sbjct: 161 GTKQAELVIIRELDREVQDSVDLSLVAWDKGDPPRSGSTLIHVRIQDSNDNSPTFEDSAP 220

Query: 263 QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322
              + EN   G +I+ ++A D D+GVN E+ Y+++ K     V   I +DP++  V    
Sbjct: 221 TVELPENTARGTTIISLKATDPDQGVNGEVVYSLS-KHTQPEVQRLIAVDPQTAAVSLKA 279

Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE-----LAE 377
            LD E Q  Y+++V A D G     A                  +            + E
Sbjct: 280 PLDYEVQTSYEVVVEARDRGPNAIPAYCKLHIKLLDVNDNAPRILADWDRSSFPGPTVLE 339

Query: 378 DEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSIT-SQNGRGLITVAQPLDFKQE 434
             P  T +  +T  DAD  ++ ++  +I  G+  G FS+   Q G   I     LD +Q 
Sbjct: 340 GAPKDTFLSLVTVLDADSGQNGKVKAQILEGS--GPFSLKHMQGGNYKIVTNGTLDREQV 397

Query: 435 RRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492
             Y LT+ A D G    S    + + + D N+ APVF    Y AS  E    G  +L V 
Sbjct: 398 TWYNLTLLAQDYGDPPLSSVKHMSVQVVDENDNAPVFSTNIYKASFEETNRTGYQMLKVE 457

Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552
           A D D+ ++ +++Y     I N   A  D  F I+  +G I     LD E    +   V 
Sbjct: 458 AHDVDLDLSGRVSYF----IRNVTGADVDAYFSIHQTSGVIRAQHRLDYEESRSHSFIVE 513

Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583
           A D G P LS +  V+I V DVNDN PV K+
Sbjct: 514 AIDQGHPPLSSSATVQIQVQDVNDNYPVIKE 544



 Score =  172 bits (419), Expect = 1e-40
 Identities = 122/389 (31%), Positives = 191/389 (49%), Gaps = 26/389 (6%)

Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480
           + + + LD + +    L++ A D G   RS + ++ + I D+N+ +P FE++  T  + E
Sbjct: 167 LVIIRELDREVQDSVDLSLVAWDKGDPPRSGSTLIHVRIQDSNDNSPTFEDSAPTVELPE 226

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           +   GTT++ + ATD D G+N ++ YSLS     E      +   ++PQT A++    LD
Sbjct: 227 NTARGTTIISLKATDPDQGVNGEVVYSLSKHTQPEV----QRLIAVDPQTAAVSLKAPLD 282

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF-----KQQLYTANIMEDAL 595
            E  + Y + V ARD G  ++     + I ++DVNDN P       +       ++E A 
Sbjct: 283 YEVQTSYEVVVEARDRGPNAIPAYCKLHIKLLDVNDNAPRILADWDRSSFPGPTVLEGAP 342

Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG---VIRTNKALDRESVAT 652
             T +S V   DAD G NG++  ++       G F +    G    I TN  LDRE V  
Sbjct: 343 KDTFLSLVTVLDADSGQNGKVKAQIL---EGSGPFSLKHMQGGNYKIVTNGTLDREQVTW 399

Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
           ++L  +A D G PP SS   + +++ D ND+ PVF ++       E +  G  + ++ AH
Sbjct: 400 YNLTLLAQDYGDPPLSSVKHMSVQVVDENDNAPVFSTNIYKASFEETNRTGYQMLKVEAH 459

Query: 713 DPDEGPNAVVHYSIK---GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV--I 767
           D D   +  V Y I+   G D    FS+    G  +A+      LDYE  R    +V  I
Sbjct: 460 DVDLDLSGRVSYFIRNVTGADVDAYFSIHQTSGVIRAQ----HRLDYEESRSHSFIVEAI 515

Query: 768 RAASPPLWNDVRVEILVTDVNDNAPVMKD 796
               PPL +   V+I V DVNDN PV+K+
Sbjct: 516 DQGHPPLSSSATVQIQVQDVNDNYPVIKE 544



 Score =  154 bits (374), Expect = 3e-35
 Identities = 107/348 (30%), Positives = 175/348 (50%), Gaps = 30/348 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + + D ND+SP FE       + E  + GTT+++LKATD D G N EV Y++   T    
Sbjct: 203 VRIQDSNDNSPTFEDSAPTVELPENTARGTTIISLKATDPDQGVNGEVVYSLSKHT---- 258

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            PE            VQ +  +D ++ A+  +A LD E    Y V+V+A D+     + +
Sbjct: 259 QPE------------VQRLIAVDPQTAAVSLKAPLDYEVQTSYEVVVEARDRGP---NAI 303

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP---VIAKIKATDADVGANSAI 187
            +   +H+ ++D NDN P+        S      +   P    ++ +   DAD G N  +
Sbjct: 304 PAYCKLHIKLLDVNDNAPRILADWDRSSFPGPTVLEGAPKDTFLSLVTVLDADSGQNGKV 363

Query: 188 RYAIIGGNTQMQFSIDSLSG-DVSLVK--TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
           +  I+ G+    FS+  + G +  +V   TLD EQV  Y L + AQD G P  S+   + 
Sbjct: 364 KAQILEGSGP--FSLKHMQGGNYKIVTNGTLDREQVTWYNLTLLAQDYGDPPLSSVKHMS 421

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG- 303
           + + D NDNAP F T++++ S  E    GY +++V+A+D D  ++  ++Y +  ++ TG 
Sbjct: 422 VQVVDENDNAPVFSTNIYKASFEETNRTGYQMLKVEAHDVDLDLSGRVSYFI--RNVTGA 479

Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
           +VD   +I   SG +    +LD E    +  +V A D G PP S++AT
Sbjct: 480 DVDAYFSIHQTSGVIRAQHRLDYEESRSHSFIVEAIDQGHPPLSSSAT 527



 Score =  151 bits (366), Expect = 3e-34
 Identities = 164/620 (26%), Positives = 249/620 (40%), Gaps = 81/620 (13%)

Query: 6   CIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIEL- 64
           C+  ++ V+D NDHSP F   + +  + E A     +   +A D D G N    Y++ + 
Sbjct: 89  CLRVRVEVMDQNDHSPQFPNAEQDVEISEIAGLRMRIPLERAVDPDAGPNGLQTYSLSVN 148

Query: 65  --VTAD-TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121
                D T+ PE                     +   L+    LDRE      + + A D
Sbjct: 149 RYFALDVTVGPEGT-------------------KQAELVIIRELDREVQDSVDLSLVAWD 189

Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181
           +  P     S +  IHV I D NDN P F +   TV + E  +      I  +KATD D 
Sbjct: 190 KGDPPR---SGSTLIHVRIQDSNDNSPTFEDSAPTVELPE--NTARGTTIISLKATDPDQ 244

Query: 182 GANSAIRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238
           G N  + Y++        Q   ++D  +  VSL   LDYE   SY +V+ A+D G  +  
Sbjct: 245 GVNGEVVYSLSKHTQPEVQRLIAVDPQTAAVSLKAPLDYEVQTSYEVVVEARDRGPNAIP 304

Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQES-----VSENVPIGYSIVRVQAYDADEGVNAELT 293
              +L I + DVNDNAPR      + S     V E  P    +  V   DAD G N ++ 
Sbjct: 305 AYCKLHIKLLDVNDNAPRILADWDRSSFPGPTVLEGAPKDTFLSLVTVLDADSGQNGKVK 364

Query: 294 YTMTDKDYTGNVDLPITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATA 350
             + +   +G    P ++    G  Y   T+G LDRE    Y L + A D GDPP S+  
Sbjct: 365 AQILEG--SG----PFSLKHMQGGNYKIVTNGTLDREQVTWYNLTLLAQDYGDPPLSSVK 418

Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHY---EITG 405
                          F    Y+    E    G  ++ + A D D D   R+ Y    +TG
Sbjct: 419 HMSVQVVDENDNAPVFSTNIYKASFEETNRTGYQMLKVEAHDVDLDLSGRVSYFIRNVTG 478

Query: 406 GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDAN 463
            +    FSI   +  G+I     LD+++ R +   V A D G    S +A VQI + D N
Sbjct: 479 ADVDAYFSIHQTS--GVIRAQHRLDYEESRSHSFIVEAIDQGHPPLSSSATVQIQVQDVN 536

Query: 464 -NYAPVFENAPYTASVFEDAPIGT---TVLVVSATDSDVGINAQITYS-------LSSEI 512
            NY  + E  P         P+      ++    T  D G  A            L+S I
Sbjct: 537 DNYPVIKEPKPRKGVASLSVPVNADKGEIVTELGTHLD-GTAASFPVDPRTRSGFLASTI 595

Query: 513 SNE--------------AVAHHDQQFVINPQTGAITTNKLLDRETM-SGYLLTVTARDGG 557
             E              A  +H++ F ++  TG +  N     + +   + L +   D G
Sbjct: 596 KAEDADSGPNGALSYRIAKGNHNRLFWLHEATGQLFVNATNATQLIGQNFKLDIAVSDMG 655

Query: 558 VPSLSDTTDVEISVVDVNDN 577
            P L+ T  +E++ +++ D+
Sbjct: 656 SPRLTTTMTLEVTFINLRDH 675



 Score =  135 bits (326), Expect = 2e-29
 Identities = 117/425 (27%), Positives = 193/425 (45%), Gaps = 24/425 (5%)

Query: 448 GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507
           G  +   V++ + D N+++P F NA     + E A +   + +  A D D G N   TYS
Sbjct: 85  GAMNCLRVRVEVMDQNDHSPQFPNAEQDVEISEIAGLRMRIPLERAVDPDAGPNGLQTYS 144

Query: 508 LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567
           LS    N   A          +   +   + LDRE      L++ A D G P  S +T +
Sbjct: 145 LS---VNRYFALDVTVGPEGTKQAELVIIRELDREVQDSVDLSLVAWDKGDPPRSGSTLI 201

Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627
            + + D NDN P F+    T  + E+   GT++  + ATD D G+NG + Y L    + E
Sbjct: 202 HVRIQDSNDNSPTFEDSAPTVELPENTARGTTIISLKATDPDQGVNGEVVYSLSKHTQPE 261

Query: 628 GS--FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685
                 +DP +  +     LD E   ++++   A D G     +   +HIK+ D+ND+ P
Sbjct: 262 VQRLIAVDPQTAAVSLKAPLDYEVQTSYEVVVEARDRGPNAIPAYCKLHIKLLDVNDNAP 321

Query: 686 --VFESDCLTF---YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR 740
             + + D  +F    + E +P  T +  +   D D G N  V   I  G  S  FSL+  
Sbjct: 322 RILADWDRSSFPGPTVLEGAPKDTFLSLVTVLDADSGQNGKVKAQILEG--SGPFSLKHM 379

Query: 741 QGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDF 797
           QG +  ++VT   LD E     Y L + A     PPL +   + + V D NDNAPV    
Sbjct: 380 QGGN-YKIVTNGTLDREQV-TWYNLTLLAQDYGDPPLSSVKHMSVQVVDENDNAPVFST- 436

Query: 798 QIIFNNYKDCFPVG-PFGRVPAYDA--DVTDKLQYRILSGNNANL---ILLNETTGSMTL 851
            I   ++++    G    +V A+D   D++ ++ Y I +   A++     +++T+G +  
Sbjct: 437 NIYKASFEETNRTGYQMLKVEAHDVDLDLSGRVSYFIRNVTGADVDAYFSIHQTSGVIRA 496

Query: 852 SPQLN 856
             +L+
Sbjct: 497 QHRLD 501



 Score =  105 bits (252), Expect = 2e-20
 Identities = 89/287 (31%), Positives = 127/287 (44%), Gaps = 29/287 (10%)

Query: 524 FVINPQTGAITTNKLLDRETMSG------YLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577
           F +  + G + T   LDRE +           +V  R  G     +   V + V+D ND+
Sbjct: 46  FSVGARDGVLATQGRLDREELCRGSDLCEVAFSVLYRKSGA---MNCLRVRVEVMDQNDH 102

Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637
            P F        I E A +   +    A D D G NG   Y L         F +D   G
Sbjct: 103 SPQFPNAEQDVEISEIAGLRMRIPLERAVDPDAGPNGLQTYSLSVNRY----FALDVTVG 158

Query: 638 VIRTNKA-------LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690
              T +A       LDRE   + DL  VA D G PP+S + ++H++I+D ND+ P FE  
Sbjct: 159 PEGTKQAELVIIRELDREVQDSVDLSLVAWDKGDPPRSGSTLIHVRIQDSNDNSPTFEDS 218

Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750
             T  + EN+  GTTI  ++A DPD+G N  V YS+          L        A +  
Sbjct: 219 APTVELPENTARGTTIISLKATDPDQGVNGEVVYSLSKHTQPEVQRL-IAVDPQTAAVSL 277

Query: 751 MVDLDYESPRKKYELVIRAA-----SPPLWNDVRVEILVTDVNDNAP 792
              LDYE  +  YE+V+ A      + P +  + +++L  DVNDNAP
Sbjct: 278 KAPLDYE-VQTSYEVVVEARDRGPNAIPAYCKLHIKLL--DVNDNAP 321


>UniRef50_UPI000054713A Cluster: PREDICTED: hypothetical protein;
           n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 1026

 Score =  185 bits (451), Expect = 1e-44
 Identities = 141/483 (29%), Positives = 231/483 (47%), Gaps = 29/483 (6%)

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           + + D+ND+ P F + L +  +SE   +   I   +A D D G N   TYT++   +   
Sbjct: 100 VEVMDLNDHNPVFPSLLQEVEISETASLRMRIPLDRAADPDAGPNGLQTYTLSSNQHFA- 158

Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
           +D+      +   +  + +LDRE QA  +L + A D G+PP+S +               
Sbjct: 159 LDVRSFGGAKQAELVVTKELDRELQASLELELIAWDKGNPPKSGSTKIIVTILDSNDNSP 218

Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGN---TRGRFSITSQNG 419
            F      +ELAE+   GT V+ L ATD D+  +  + Y ++  +    +  FSI  + G
Sbjct: 219 IFEEAPSVIELAENTIRGTIVLNLRATDPDQGANGEVEYSLSKHSPLEVQRLFSIHPKTG 278

Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFE------N 471
              +T+  PLDF+++  Y + + A D G  G      +QI + D N+ AP         +
Sbjct: 279 A--LTLQGPLDFEEKNVYEVDIQARDLGPNGIPSHHKLQIKLQDINDNAPRIHITWTPPD 336

Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531
           +P  A+V E AP  T + +V  +D+D G N Q+   +   ++        Q   I+    
Sbjct: 337 SP-VATVTEGAPNETFLALVMVSDADYGANGQVQVHI---LTGSGPFRLKQ---IHGDNY 389

Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
            I TN  LDRE    Y LT+ A+D G PSLS    + + V+D NDN P+F +  Y + + 
Sbjct: 390 MIVTNGTLDREKQMEYNLTLLAQDSGDPSLSCIKHLTVHVLDENDNPPIFTKSHYRSILK 449

Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS----FVIDPASGVIRTNKALDR 647
           E+   G     V A D D+GL+G++ + +  +  E G+    F + P+SG +   ++LD 
Sbjct: 450 ENNTPGFHFLTVEAHDVDLGLSGQVSFSI-RESNELGTPTAFFSVHPSSGEVTVQQSLDY 508

Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS-ENSPIGTTI 706
           E    +     A+D G PP +S   V ++I+D+ND+ P+         I+  N P+    
Sbjct: 509 EESRVYSFIVEAVDQGYPPMTSIAAVLVEIQDVNDNYPIIYEPLPKKGIALLNVPVNVDK 568

Query: 707 GEI 709
           GEI
Sbjct: 569 GEI 571



 Score =  161 bits (391), Expect = 3e-37
 Identities = 134/508 (26%), Positives = 228/508 (44%), Gaps = 23/508 (4%)

Query: 92  IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151
           +  R G + T   LDRE++   T L +                ++ V ++D ND+ P F 
Sbjct: 54  VASRDGTVSTFGRLDREELCWGTELCELAFNVLYRKGGAMHLLSVRVEVMDLNDHNPVFP 113

Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG---- 207
                V + E  S+     I   +A D D G N    Y +   N      + S  G    
Sbjct: 114 SLLQEVEISETASLRMR--IPLDRAADPDAGPNGLQTYTL-SSNQHFALDVRSFGGAKQA 170

Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
           ++ + K LD E   S  L + A D G+P +S +T++++ I D NDN+P F  +     ++
Sbjct: 171 ELVVTKELDRELQASLELELIAWDKGNPPKSGSTKIIVTILDSNDNSPIFEEAPSVIELA 230

Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
           EN   G  ++ ++A D D+G N E+ Y+++ K     V    +I P++G +   G LD E
Sbjct: 231 ENTIRGTIVLNLRATDPDQGANGEVEYSLS-KHSPLEVQRLFSIHPKTGALTLQGPLDFE 289

Query: 328 TQAKYQLLVTATD---GGDPP-RSATATXXXXXXXXXXXXXXFMPGQYEV-ELAEDEPPG 382
            +  Y++ + A D    G P                      + P    V  + E  P  
Sbjct: 290 EKNVYEVDIQARDLGPNGIPSHHKLQIKLQDINDNAPRIHITWTPPDSPVATVTEGAPNE 349

Query: 383 TPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ-PLDFKQERRYVL 439
           T +  +  +DAD   + ++   I  G+  G F +   +G   + V    LD +++  Y L
Sbjct: 350 TFLALVMVSDADYGANGQVQVHILTGS--GPFRLKQIHGDNYMIVTNGTLDREKQMEYNL 407

Query: 440 TVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497
           T+ A DSG  S + +  + +++ D N+  P+F  + Y + + E+   G   L V A D D
Sbjct: 408 TLLAQDSGDPSLSCIKHLTVHVLDENDNPPIFTKSHYRSILKENNTPGFHFLTVEAHDVD 467

Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG 557
           +G++ Q+++S+    SNE +      F ++P +G +T  + LD E    Y   V A D G
Sbjct: 468 LGLSGQVSFSIRE--SNE-LGTPTAFFSVHPSSGEVTVQQSLDYEESRVYSFIVEAVDQG 524

Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQL 585
            P ++    V + + DVNDN P+  + L
Sbjct: 525 YPPMTSIAAVLVEIQDVNDNYPIIYEPL 552



 Score =  161 bits (390), Expect = 3e-37
 Identities = 140/507 (27%), Positives = 218/507 (42%), Gaps = 27/507 (5%)

Query: 307 LPITIDPRSGWVYTSGQLDRE-----TQ-AKYQLLVTATDGGDPPRSATATXXXXXXXXX 360
           LP+T+  R G V T G+LDRE     T+  +    V    GG     +            
Sbjct: 50  LPVTVASRDGTVSTFGRLDREELCWGTELCELAFNVLYRKGGAMHLLSVRVEVMDLNDHN 109

Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQNG 419
                 +    EVE++E       +    A D D   N L       N      + S  G
Sbjct: 110 PVFPSLLQ---EVEISETASLRMRIPLDRAADPDAGPNGLQTYTLSSNQHFALDVRSFGG 166

Query: 420 --RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYT 475
             +  + V + LD + +    L + A D G   +S +  + + I D+N+ +P+FE AP  
Sbjct: 167 AKQAELVVTKELDRELQASLELELIAWDKGNPPKSGSTKIIVTILDSNDNSPIFEEAPSV 226

Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
             + E+   GT VL + ATD D G N ++ YSLS     E      + F I+P+TGA+T 
Sbjct: 227 IELAENTIRGTIVLNLRATDPDQGANGEVEYSLSKHSPLEV----QRLFSIHPKTGALTL 282

Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK-----QQLYTANI 590
              LD E  + Y + + ARD G   +     ++I + D+NDN P             A +
Sbjct: 283 QGPLDFEEKNVYEVDIQARDLGPNGIPSHHKLQIKLQDINDNAPRIHITWTPPDSPVATV 342

Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650
            E A   T ++ V  +DAD G NG++   +           I   + +I TN  LDRE  
Sbjct: 343 TEGAPNETFLALVMVSDADYGANGQVQVHILTGSGPFRLKQIHGDNYMIVTNGTLDREKQ 402

Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710
             ++L  +A D G P  S    + + + D ND+PP+F        + EN+  G     + 
Sbjct: 403 MEYNLTLLAQDSGDPSLSCIKHLTVHVLDENDNPPIFTKSHYRSILKENNTPGFHFLTVE 462

Query: 711 AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770
           AHD D G +  V +SI+  ++  + +          E+     LDYE  R  Y  ++ A 
Sbjct: 463 AHDVDLGLSGQVSFSIRESNELGTPTAFFSVHPSSGEVTVQQSLDYEESR-VYSFIVEAV 521

Query: 771 S---PPLWNDVRVEILVTDVNDNAPVM 794
               PP+ +   V + + DVNDN P++
Sbjct: 522 DQGYPPMTSIAAVLVEIQDVNDNYPII 548



 Score =  157 bits (382), Expect = 3e-36
 Identities = 140/494 (28%), Positives = 214/494 (43%), Gaps = 47/494 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ V+D NDH+PVF     E  + E AS    +   +A D D G N    YT+      +
Sbjct: 99  RVEVMDLNDHNPVFPSLLQEVEISETASLRMRIPLDRAADPDAGPNGLQTYTL------S 152

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
            N   A            DV    G +   L+    LDRE  A   + + A D+ +P   
Sbjct: 153 SNQHFAL-----------DVRSFGGAKQAELVVTKELDRELQASLELELIAWDKGNPPK- 200

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             S +  I V I+D NDN P F E    + + E  +     ++  ++ATD D GAN  + 
Sbjct: 201 --SGSTKIIVTILDSNDNSPIFEEAPSVIELAE--NTIRGTIVLNLRATDPDQGANGEVE 256

Query: 189 YAIIGGN---TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
           Y++   +    Q  FSI   +G ++L   LD+E+   Y + I+A+D G     +  +L I
Sbjct: 257 YSLSKHSPLEVQRLFSIHPKTGALTLQGPLDFEEKNVYEVDIQARDLGPNGIPSHHKLQI 316

Query: 246 NIRDVNDNAPRFYTSLFQ-----ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
            ++D+NDNAPR + +         +V+E  P    +  V   DAD G N ++   +    
Sbjct: 317 KLQDINDNAPRIHITWTPPDSPVATVTEGAPNETFLALVMVSDADYGANGQVQVHI---- 372

Query: 301 YTGNVDLPI-TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
            TG+    +  I   +  + T+G LDRE Q +Y L + A D GDP  S            
Sbjct: 373 LTGSGPFRLKQIHGDNYMIVTNGTLDREKQMEYNLTLLAQDSGDPSLSCIKHLTVHVLDE 432

Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGR----FS 413
                 F    Y   L E+  PG   +T+ A D D     ++ + I   N  G     FS
Sbjct: 433 NDNPPIFTKSHYRSILKENNTPGFHFLTVEAHDVDLGLSGQVSFSIRESNELGTPTAFFS 492

Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDAN-NYAPVFE 470
           +   +G   +TV Q LD+++ R Y   V A D G    +  A V + I D N NY  ++E
Sbjct: 493 VHPSSGE--VTVQQSLDYEESRVYSFIVEAVDQGYPPMTSIAAVLVEIQDVNDNYPIIYE 550

Query: 471 NAPYTASVFEDAPI 484
             P       + P+
Sbjct: 551 PLPKKGIALLNVPV 564



 Score =  106 bits (255), Expect = 8e-21
 Identities = 89/294 (30%), Positives = 137/294 (46%), Gaps = 25/294 (8%)

Query: 515 EAVAH-HDQQFVINPQTGAITTNKLLDRETMSG------YLLTVTARDGGVPSLSDTTDV 567
           + V H H     +  + G ++T   LDRE +            V  R GG   L     V
Sbjct: 42  QVVQHGHALPVTVASRDGTVSTFGRLDREELCWGTELCELAFNVLYRKGGAMHL---LSV 98

Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR-- 625
            + V+D+ND+ PVF   L    I E A +   +    A D D G NG   Y L       
Sbjct: 99  RVEVMDLNDHNPVFPSLLQEVEISETASLRMRIPLDRAADPDAGPNGLQTYTLSSNQHFA 158

Query: 626 -EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP 684
            +  SF     + ++ T K LDRE  A+ +L+ +A D G PP+S +  + + I D ND+ 
Sbjct: 159 LDVRSFGGAKQAELVVT-KELDRELQASLELELIAWDKGNPPKSGSTKIIVTILDSNDNS 217

Query: 685 PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG---DDSNSFSLETRQ 741
           P+FE       ++EN+  GT +  +RA DPD+G N  V YS+      +    FS+  + 
Sbjct: 218 PIFEEAPSVIELAENTIRGTIVLNLRATDPDQGANGEVEYSLSKHSPLEVQRLFSIHPKT 277

Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792
           G+    L     LD+E  +  YE+ I+A       + +  +++I + D+NDNAP
Sbjct: 278 GA----LTLQGPLDFEE-KNVYEVDIQARDLGPNGIPSHHKLQIKLQDINDNAP 326



 Score = 70.1 bits (164), Expect = 8e-10
 Identities = 57/224 (25%), Positives = 105/224 (46%), Gaps = 13/224 (5%)

Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732
           V +++ D+ND  PVF S      ISE + +   I   RA DPD GPN +  Y++     +
Sbjct: 98  VRVEVMDLNDHNPVFPSLLQEVEISETASLRMRIPLDRAADPDAGPNGLQTYTLSS---N 154

Query: 733 NSFSLETRQ--GSDKAELVTMVDLDYESPRK-KYELVI-RAASPPLWNDVRVEILVTDVN 788
             F+L+ R   G+ +AELV   +LD E     + EL+     +PP     ++ + + D N
Sbjct: 155 QHFALDVRSFGGAKQAELVVTKELDRELQASLELELIAWDKGNPPKSGSTKIIVTILDSN 214

Query: 789 DNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNN---ANLILLN 843
           DN+P+ ++   +    ++         + A D D     +++Y +   +      L  ++
Sbjct: 215 DNSPIFEEAPSVIELAENTIRGTIVLNLRATDPDQGANGEVEYSLSKHSPLEVQRLFSIH 274

Query: 844 ETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRL 886
             TG++TL   L+     +  +++   D G N I +  +L ++L
Sbjct: 275 PKTGALTLQGPLDFEEKNVYEVDIQARDLGPNGIPSHHKLQIKL 318



 Score = 64.1 bits (149), Expect = 5e-08
 Identities = 66/266 (24%), Positives = 118/266 (44%), Gaps = 25/266 (9%)

Query: 6   CI-HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIEL 64
           CI H  ++VLD ND+ P+F    Y + ++E  + G   LT++A D D+G + +V ++I  
Sbjct: 421 CIKHLTVHVLDENDNPPIFTKSHYRSILKENNTPGFHFLTVEAHDVDLGLSGQVSFSIR- 479

Query: 65  VTADTLNPEDAXXXXXXXXXXV---QDVFRIDGRSGALLTRASLDR-----EKVARYTVL 116
             ++ L    A          V   Q +   + R  + +  A +D+       +A   V 
Sbjct: 480 -ESNELGTPTAFFSVHPSSGEVTVQQSLDYEESRVYSFIVEA-VDQGYPPMTSIAAVLVE 537

Query: 117 VKATDQASPVS-DRLSSTATIHVNI---IDDNDNYPQFSEKTYTVSVDE--DISVTDNP- 169
           ++  +   P+  + L       +N+   +D  +   +  +K    +  +  + S  + P 
Sbjct: 538 IQDVNDNYPIIYEPLPKKGIALLNVPVNVDKGEIVTELGDKAMEDNFHKHRNYSSLNKPE 597

Query: 170 --VIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV-RSYRLV 226
             +   I+A+D D G N  + + I GGN    F +D  SG+  +  T   E + R+++L 
Sbjct: 598 GFLATTIRASDPDSGLNGRLNFGITGGNPSNIFFLDKTSGEFYVNTTNATELIGRTFKLG 657

Query: 227 IRAQDGGSPSRSNTTQL---LINIRD 249
           I   D G+P  S  T L    IN RD
Sbjct: 658 IEVSDMGTPILSTRTTLEVTFINFRD 683



 Score = 41.9 bits (94), Expect = 0.25
 Identities = 21/48 (43%), Positives = 26/48 (54%)

Query: 695 YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742
           Y S N P G     IRA DPD G N  +++ I GG+ SN F L+   G
Sbjct: 590 YSSLNKPEGFLATTIRASDPDSGLNGRLNFGITGGNPSNIFFLDKTSG 637


>UniRef50_Q7YZI2 Cluster: PRCDH1; n=1; Proterospongia sp. ATCC
           50818|Rep: PRCDH1 - Proterospongia sp. ATCC 50818
          Length = 496

 Score =  185 bits (451), Expect = 1e-44
 Identities = 155/523 (29%), Positives = 254/523 (48%), Gaps = 44/523 (8%)

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ-FSIDSLS 206
           P F++    V++ E  S+ D   + +++ATD D    + IRY ++ G+T    F +D++ 
Sbjct: 8   PVFTQDLVRVTLLETASLGD--YVTRVEATDQDCADEAEIRYRVVSGDTTPPTFDLDTVG 65

Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266
           G ++LV+ LD+ +  S+ L + A DG     S+T  +LIN+ + + + P F +S +   +
Sbjct: 66  GVITLVRELDFAERSSFSLQLSASDG---DLSDTMYVLINVVETSPDFPLFTSSRYTADL 122

Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326
           +E+  IG ++  V       G+    ++++T     GN      +D  SG +    ++  
Sbjct: 123 AESASIGTTVATVATNRT--GI---ASFSITG----GNSAGKFAVDANSGAITLMSRVCA 173

Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386
            ++  Y L V A     P   +                 F   QY V ++E    G+ ++
Sbjct: 174 ASEDAYSLQVQAQSKTRPDLQSYTLVDVSVVPANTAAPAFSQAQYSVNVSETGSVGSVLL 233

Query: 387 TLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE----RRYVLTVS 442
            L ATDAD  + + Y ITGGN+ G F+I  + G   + V QPL+         ++ LTV+
Sbjct: 234 QLQATDADCRDAVTYRITGGNSNGLFAINRETGE--LAVVQPLNADVSSGGAAQHTLTVA 291

Query: 443 ATD---SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499
           ATD   S  R+ TA V + + + N YAPVF  A Y+ +  +    GT +++V ATD+D G
Sbjct: 292 ATDDFASSPRTSTATVLVTVLNVNQYAPVFA-ATYSGTFADSVSTGTELVLVGATDAD-G 349

Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
            N  I Y+++S        +    F I+  TG++T    +   T S Y L VTA D G P
Sbjct: 350 DN--IAYAITS-------GNTGNVFAIDAVTGSLTLAAPVCSRTQSSYTLVVTATDDGQP 400

Query: 560 -SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618
            + S  T V++S    N   PVF+Q  Y  +   D+ +     +V ATDAD   +  I Y
Sbjct: 401 EARSAGTVVQLSFSASNAASPVFEQASY--SFTADSSLNAYAGRVRATDAD--CDDSITY 456

Query: 619 ELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
            L+     + +F I P +GVI     L +++   + L AVA D
Sbjct: 457 TLN--RNTQFAFTIHPTTGVITVVAPLTQDT--PYVLDAVATD 495



 Score =  167 bits (407), Expect = 3e-39
 Identities = 154/544 (28%), Positives = 253/544 (46%), Gaps = 63/544 (11%)

Query: 20  SPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXX 79
           +PVF       ++ E AS G  V  ++ATDQD    AE+ Y +  V+ DT  P       
Sbjct: 7   APVFTQDLVRVTLLETASLGDYVTRVEATDQDCADEAEIRYRV--VSGDTTPP------- 57

Query: 80  XXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVN 139
                     F +D   G +     LD  + + +++ + A+D        LS T  + +N
Sbjct: 58  ---------TFDLDTVGGVITLVRELDFAERSSFSLQLSASD------GDLSDTMYVLIN 102

Query: 140 IIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ 199
           +++ + ++P F+   YT  + E  S+     +A +      + +     ++I GGN+  +
Sbjct: 103 VVETSPDFPLFTSSRYTADLAESASI--GTTVATVATNRTGIAS-----FSITGGNSAGK 155

Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259
           F++D+ SG ++L+  +      +Y L ++AQ    P   + T + +++   N  AP F  
Sbjct: 156 FAVDANSGAITLMSRVCAASEDAYSLQVQAQSKTRPDLQSYTLVDVSVVPANTAAPAFSQ 215

Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319
           + +  +VSE   +G  ++++QA DAD      +TY +T     GN +    I+  +G + 
Sbjct: 216 AQYSVNVSETGSVGSVLLQLQATDAD--CRDAVTYRITG----GNSNGLFAINRETGELA 269

Query: 320 TSGQLDRETQ----AKYQLLVTATDG-GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374
               L+ +      A++ L V ATD     PR++TAT              F    Y   
Sbjct: 270 VVQPLNADVSSGGAAQHTLTVAATDDFASSPRTSTATVLVTVLNVNQYAPVF-AATYSGT 328

Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434
            A+    GT +V + ATDAD DN + Y IT GNT   F+I +  G   +T+A P+  + +
Sbjct: 329 FADSVSTGTELVLVGATDADGDN-IAYAITSGNTGNVFAIDAVTGS--LTLAAPVCSRTQ 385

Query: 435 RRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491
             Y L V+ATD G    RS   +VQ++ + +N  +PVFE A Y  S   D+ +      V
Sbjct: 386 SSYTLVVTATDDGQPEARSAGTVVQLSFSASNAASPVFEQASY--SFTADSSLNAYAGRV 443

Query: 492 SATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTV 551
            ATD+D   +  ITY+L+    N   A     F I+P TG IT    L ++T   Y+L  
Sbjct: 444 RATDAD--CDDSITYTLN---RNTQFA-----FTIHPTTGVITVVAPLTQDT--PYVLDA 491

Query: 552 TARD 555
            A D
Sbjct: 492 VATD 495



 Score =  144 bits (350), Expect = 2e-32
 Identities = 139/499 (27%), Positives = 227/499 (45%), Gaps = 40/499 (8%)

Query: 373 VELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
           V L E    G  V  + ATD D  ++  + Y +  G+T          G G+IT+ + LD
Sbjct: 17  VTLLETASLGDYVTRVEATDQDCADEAEIRYRVVSGDTTPPTFDLDTVG-GVITLVRELD 75

Query: 431 FKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
           F +   + L +SA+D G  SDT  V IN+ + +   P+F ++ YTA + E A IGTTV  
Sbjct: 76  FAERSSFSLQLSASD-GDLSDTMYVLINVVETSPDFPLFTSSRYTADLAESASIGTTVAT 134

Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550
           V+   + +      ++S++    N A      +F ++  +GAIT    +   +   Y L 
Sbjct: 135 VATNRTGIA-----SFSITG--GNSA-----GKFAVDANSGAITLMSRVCAASEDAYSLQ 182

Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610
           V A+    P L   T V++SVV  N   P F Q  Y+ N+ E   VG+ + Q+ ATDAD 
Sbjct: 183 VQAQSKTRPDLQSYTLVDVSVVPANTAAPAFSQAQYSVNVSETGSVGSVLLQLQATDAD- 241

Query: 611 GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE----SVATHDLKAVAIDG-GTP 665
                + Y +       G F I+  +G +   + L+ +      A H L   A D   + 
Sbjct: 242 -CRDAVTYRI-TGGNSNGLFAINRETGELAVVQPLNADVSSGGAAQHTLTVAATDDFASS 299

Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
           P++ST  V + + ++N   PVF +   +   +++   GT +  + A D D G N  + Y+
Sbjct: 300 PRTSTATVLVTVLNVNQYAPVFAA-TYSGTFADSVSTGTELVLVGATDAD-GDN--IAYA 355

Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN-DVRVE 781
           I  G+  N F+++   GS     +T+        +  Y LV+ A     P   +    V+
Sbjct: 356 ITSGNTGNVFAIDAVTGS-----LTLAAPVCSRTQSSYTLVVTATDDGQPEARSAGTVVQ 410

Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLIL 841
           +  +  N  +PV +  Q  ++   D       GRV A DAD  D + Y  L+ N      
Sbjct: 411 LSFSASNAASPVFE--QASYSFTADSSLNAYAGRVRATDADCDDSITY-TLNRNTQFAFT 467

Query: 842 LNETTGSMTLSPQLNTNVP 860
           ++ TTG +T+   L  + P
Sbjct: 468 IHPTTGVITVVAPLTQDTP 486



 Score =  144 bits (348), Expect = 4e-32
 Identities = 130/471 (27%), Positives = 206/471 (43%), Gaps = 37/471 (7%)

Query: 254 APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313
           AP F   L + ++ E   +G  + RV+A D D    AE+ Y +   D T        +D 
Sbjct: 7   APVFTQDLVRVTLLETASLGDYVTRVEATDQDCADEAEIRYRVVSGDTTPPT---FDLDT 63

Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373
             G +    +LD   ++ + L ++A+DG     S T                F   +Y  
Sbjct: 64  VGGVITLVRELDFAERSSFSLQLSASDG---DLSDTMYVLINVVETSPDFPLFTSSRYTA 120

Query: 374 ELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ 433
           +LAE    GT V T+     +      + ITGGN+ G+F++ + +  G IT+   +    
Sbjct: 121 DLAESASIGTTVATVA---TNRTGIASFSITGGNSAGKFAVDANS--GAITLMSRVCAAS 175

Query: 434 ERRYVLTVSATDSGGRSDT---AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
           E  Y L V A  S  R D     +V +++  AN  AP F  A Y+ +V E   +G+ +L 
Sbjct: 176 EDAYSLQVQA-QSKTRPDLQSYTLVDVSVVPANTAAPAFSQAQYSVNVSETGSVGSVLLQ 234

Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG---- 546
           + ATD+D      +TY ++   SN         F IN +TG +   + L+ +  SG    
Sbjct: 235 LQATDAD--CRDAVTYRITGGNSNGL-------FAINRETGELAVVQPLNADVSSGGAAQ 285

Query: 547 YLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605
           + LTV A D    S  + T  V ++V++VN   PVF    Y+    +    GT +  VGA
Sbjct: 286 HTLTVAATDDFASSPRTSTATVLVTVLNVNQYAPVF-AATYSGTFADSVSTGTELVLVGA 344

Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665
           TDAD      I Y +         F ID  +G +     +   + +++ L   A D G P
Sbjct: 345 TDAD---GDNIAYAI-TSGNTGNVFAIDAVTGSLTLAAPVCSRTQSSYTLVVTATDDGQP 400

Query: 666 -PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
             +S+  +V +     N + PVFE    +F  + +S +    G +RA D D
Sbjct: 401 EARSAGTVVQLSFSASNAASPVFEQASYSF--TADSSLNAYAGRVRATDAD 449



 Score =  128 bits (308), Expect = 3e-27
 Identities = 116/413 (28%), Positives = 185/413 (44%), Gaps = 28/413 (6%)

Query: 465 YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524
           +APVF       ++ E A +G  V  V ATD D    A+I Y +   +S +        F
Sbjct: 6   FAPVFTQDLVRVTLLETASLGDYVTRVEATDQDCADEAEIRYRV---VSGDTTP---PTF 59

Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584
            ++   G IT  + LD    S + L ++A DG    LSDT  V I+VV+ + + P+F   
Sbjct: 60  DLDTVGGVITLVRELDFAERSSFSLQLSASDG---DLSDTMYVLINVVETSPDFPLFTSS 116

Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA 644
            YTA++ E A +GT+V+ V AT+      G   + +   +   G F +D  SG I     
Sbjct: 117 RYTADLAESASIGTTVATV-ATNR----TGIASFSITGGN-SAGKFAVDANSGAITLMSR 170

Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
           +   S   + L+  A     P   S  +V + +   N + P F     +  +SE   +G+
Sbjct: 171 VCAASEDAYSLQVQAQSKTRPDLQSYTLVDVSVVPANTAAPAFSQAQYSVNVSETGSVGS 230

Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP-RKKY 763
            + +++A D D      V Y I GG+ +  F++    G  +  +V  ++ D  S    ++
Sbjct: 231 VLLQLQATDAD--CRDAVTYRITGGNSNGLFAINRETG--ELAVVQPLNADVSSGGAAQH 286

Query: 764 ELVIRA----ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPA 818
            L + A    AS P  +   V + V +VN  APV          + D    G     V A
Sbjct: 287 TLTVAATDDFASSPRTSTATVLVTVLNVNQYAPVFA--ATYSGTFADSVSTGTELVLVGA 344

Query: 819 YDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            DAD  D + Y I SGN  N+  ++  TGS+TL+  + +      T+ V+ TD
Sbjct: 345 TDAD-GDNIAYAITSGNTGNVFAIDAVTGSLTLAAPVCSRTQSSYTLVVTATD 396



 Score =  107 bits (256), Expect = 6e-21
 Identities = 90/346 (26%), Positives = 151/346 (43%), Gaps = 22/346 (6%)

Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638
           PVF Q L    ++E A +G  V++V ATD D      I Y +   D    +F +D   GV
Sbjct: 8   PVFTQDLVRVTLLETASLGDYVTRVEATDQDCADEAEIRYRVVSGDTTPPTFDLDTVGGV 67

Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698
           I   + LD    ++  L+  A DG     S T+ V I + + +   P+F S   T  ++E
Sbjct: 68  ITLVRELDFAERSSFSLQLSASDGDL---SDTMYVLINVVETSPDFPLFTSSRYTADLAE 124

Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758
           ++ IGTT+  +  +        +  +SI GG+ +  F+++   G+     +T++     +
Sbjct: 125 SASIGTTVATVATN-----RTGIASFSITGGNSAGKFAVDANSGA-----ITLMSRVCAA 174

Query: 759 PRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR 815
               Y L ++A S   P L +   V++ V   N  AP     Q   N  +         +
Sbjct: 175 SEDAYSLQVQAQSKTRPDLQSYTLVDVSVVPANTAAPAFSQAQYSVNVSETGSVGSVLLQ 234

Query: 816 VPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE 875
           + A DAD  D + YRI  GN+  L  +N  TG + +   LN +V      + ++T    +
Sbjct: 235 LQATDADCRDAVTYRITGGNSNGLFAINRETGELAVVQPLNADVSSGGAAQHTLTVAATD 294

Query: 876 IKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLA 921
             A    S R  T  +L+  + V   +  A  F +   G F D ++
Sbjct: 295 DFAS---SPRTSTATVLVTVLNV---NQYAPVFAATYSGTFADSVS 334



 Score = 95.9 bits (228), Expect = 1e-17
 Identities = 102/331 (30%), Positives = 155/331 (46%), Gaps = 37/331 (11%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           ++V+  N  +P F   QY  +V E  S G+ +L L+ATD D  ++A V Y I   T    
Sbjct: 201 VSVVPANTAAPAFSQAQYSVNVSETGSVGSVLLQLQATDADC-RDA-VTYRI---TGGNS 255

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
           N   A          VQ +   D  SG             A++T+ V ATD  +  S   
Sbjct: 256 NGLFAINRETGELAVVQPL-NADVSSGG-----------AAQHTLTVAATDDFA--SSPR 301

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           +STAT+ V +++ N   P F+  TY+ +  + +S     V+  + ATDAD G N  I YA
Sbjct: 302 TSTATVLVTVLNVNQYAPVFA-ATYSGTFADSVSTGTELVL--VGATDAD-GDN--IAYA 355

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP-SRSNTTQLLINIRD 249
           I  GNT   F+ID+++G ++L   +      SY LV+ A D G P +RS  T + ++   
Sbjct: 356 ITSGNTGNVFAIDAVTGSLTLAAPVCSRTQSSYTLVVTATDDGQPEARSAGTVVQLSFSA 415

Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309
            N  +P F  + +  S + +  +     RV+A DAD   +  +TYT+       N     
Sbjct: 416 SNAASPVFEQASY--SFTADSSLNAYAGRVRATDAD--CDDSITYTL-----NRNTQFAF 466

Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATD 340
           TI P +G +     L ++T   Y L   ATD
Sbjct: 467 TIHPTTGVITVVAPLTQDT--PYVLDAVATD 495


>UniRef50_UPI000065EA2C Cluster: Homolog of Homo sapiens
           "Protocadherin LKC precursor; n=1; Takifugu
           rubripes|Rep: Homolog of Homo sapiens "Protocadherin LKC
           precursor - Takifugu rubripes
          Length = 1174

 Score =  185 bits (450), Expect = 2e-44
 Identities = 166/544 (30%), Positives = 260/544 (47%), Gaps = 47/544 (8%)

Query: 104 SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI 163
           +LD E   +  + V A D+      +  STAT+ ++IID NDN P+F + TY +SV E  
Sbjct: 401 NLDYEVKQQMILKVVAIDEGE---SKFRSTATVTISIIDTNDNSPKFPKDTYKLSVPEHA 457

Query: 164 SVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLV-KTLDYEQVRS 222
           S  +  VIA I A D D      IRY ++  +    F +D+ +G V +   TL   +VRS
Sbjct: 458 S--NGMVIANITAEDPDTMDRGNIRYRLLPDSILQYFGVDNRTGAVFVKNSTLLDREVRS 515

Query: 223 -YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA 281
            + + ++A+D  S  ++ +T+L I + D+ND  P      +Q  V E    G   ++++A
Sbjct: 516 LHSVTLQARD--SEDKTGSTELEITVTDINDQYPVINRDSYQVFVKEG---GDFNLKIEA 570

Query: 282 YDAD--EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE-----TQAKYQL 334
            DAD    +N+++ Y ++   Y+ N     TIDP SG +  SG LDRE      Q + +L
Sbjct: 571 TDADMPNTLNSQIVYAISPSTYSDN----FTIDPNSGVLTNSGNLDREFLDSKLQGRVEL 626

Query: 335 LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394
           +VTATD G PP S+  T              F    Y   + E +  G  V ++ A D D
Sbjct: 627 IVTATDKGTPPLSSNVTVIVNIEDINDNIPQFSNASYTFSVKEGQ-KGAYVGSVYAEDLD 685

Query: 395 ---EDNRLHYEITGGNTRGRFSITS--QNGRGL-----ITVAQPLDFKQERRYVLTVSAT 444
              E NR+ + I  G++ G F I S  ++GRG      +     LD++  R   L + A 
Sbjct: 686 QTTEFNRISFSIVDGSS-GSFIIRSFAEDGRGYRGDIRVDPDVELDYESIRNQTLRIEAA 744

Query: 445 DSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504
           D   RS  A+V++N+ D N+  P F       SV E+     TV   +A D D   N  +
Sbjct: 745 DLEQRSAEAVVKVNVLDVNDERPEF-GPIEPVSVKENTNNTETVGKFTAYDRDG--NHSL 801

Query: 505 TYSLSSE--ISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD----GGV 558
            Y L S     N+++   +   +       +  N L+D E     L+     D     G 
Sbjct: 802 LYELESIQCKCNDSMTSCNSFILDTTGEVRVNPNDLVDYEKCDQVLIEAQVVDQFTEKGE 861

Query: 559 PSLSDTTDVEISVVDVNDNEP--VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616
            + + T  + I++ DVNDN P  ++   ++   + E A  GTSV+ V ATD D GLN ++
Sbjct: 862 NNSAKTGLMVINIEDVNDNAPEFIYSDSVFVV-VSESASKGTSVAGVTATDRDSGLNRQM 920

Query: 617 HYEL 620
            +++
Sbjct: 921 EFKV 924



 Score =  159 bits (386), Expect = 1e-36
 Identities = 188/725 (25%), Positives = 309/725 (42%), Gaps = 86/725 (11%)

Query: 178 DADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRL-VIRAQDGGSPS 236
           DA    N  + + +IG N+   FS++  +G V + +TLD E +  Y   V + Q      
Sbjct: 8   DASDPENDPLTFELIGPNSGF-FSVEQGTGRVFIDQTLDREWIIYYVCGVFQIQ------ 60

Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
                 L I +++ NDN P F  S +     E+  +G S+    A D D      + Y++
Sbjct: 61  ----RDLTIFLKEANDNKPIFQQSSYDTKTPEDTAVGASLFTALAEDRDLSNAGAVRYSI 116

Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDPP-------RSA 348
            +   +  V+L   I+  SG V+ +G L+  T +  YQL + ATDGG           S 
Sbjct: 117 DEVIPSSGVNL-FRIN-ASGVVWLNGSLNYNTLSTFYQLKINATDGGGRCFYNETNFWSN 174

Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGG 406
                            F+   Y   + E+ P    V T+ A D D+  ++ + Y I G 
Sbjct: 175 VVFSFITIVDVPDLNPMFLGLPYVASVEENSPVNHSVFTVNAFDQDKGINDAIIYSIEGS 234

Query: 407 NTRGRFSITSQNGRGLITVAQPLDFKQERRYV-LTVSATDSGG------RSDTAMVQINI 459
            T G F I+S +  G+I+VA P+D +     V LTV AT+S         + T  VQINI
Sbjct: 235 TTEGLFKISSDD--GVISVAGPIDREVTGDTVNLTVKATESKQDVHGVFANTTVQVQINI 292

Query: 460 TDANNYAPVF--------ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE 511
            D N+  P F          + +T  V E   +G+  + ++  D D    + IT +   +
Sbjct: 293 QDVNDNGPEFYKCGFYCVNTSHFTGEVLEHF-LGSISINMTVKDPDRVSRSTITRTPEPK 351

Query: 512 I-------------SNEAVAHHDQQ--FVINPQTGAITTNKLL--------DRETMSGYL 548
           +               + +   + +  F + P++     N  L        D E     +
Sbjct: 352 VWLRVTLTIFPKTPRTQLILEGEDKDVFSVQPESLVSGINVQLQVKQPQNLDYEVKQQMI 411

Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
           L V A D G      T  V IS++D NDN P F +  Y  ++ E A  G  ++ + A D 
Sbjct: 412 LKVVAIDEGESKFRSTATVTISIIDTNDNSPKFPKDTYKLSVPEHASNGMVIANITAEDP 471

Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGV--IRTNKALDRESVATHDLKAVAIDGGTPP 666
           D    G I Y L P D     F +D  +G   ++ +  LDRE  + H +   A D  +  
Sbjct: 472 DTMDRGNIRYRLLP-DSILQYFGVDNRTGAVFVKNSTLLDREVRSLHSVTLQARD--SED 528

Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
           ++ +  + I + DIND  PV   D    ++ E       I    A  P+   N+ + Y+I
Sbjct: 529 KTGSTELEITVTDINDQYPVINRDSYQVFVKEGGDFNLKIEATDADMPNT-LNSQIVYAI 587

Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYE----SPRKKYELVIRA---ASPPLWNDVR 779
                S++F+++   G     L    +LD E      + + EL++ A    +PPL ++V 
Sbjct: 588 SPSTYSDNFTIDPNSG----VLTNSGNLDREFLDSKLQGRVELIVTATDKGTPPLSSNVT 643

Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVT---DKLQYRILSGNN 836
           V + + D+NDN P   +    F + K+       G V A D D T   +++ + I+ G++
Sbjct: 644 VIVNIEDINDNIPQFSNASYTF-SVKEGQKGAYVGSVYAEDLDQTTEFNRISFSIVDGSS 702

Query: 837 ANLIL 841
            + I+
Sbjct: 703 GSFII 707



 Score =  149 bits (360), Expect = 1e-33
 Identities = 172/604 (28%), Positives = 267/604 (44%), Gaps = 80/604 (13%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I+++D ND+SP F    Y+ SV E AS+G  +  + A D D      + Y         L
Sbjct: 432 ISIIDTNDNSPKFPKDTYKLSVPEHASNGMVIANITAEDPDTMDRGNIRYR--------L 483

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS--LDREKVARYTVLVKATDQASPVSD 128
            P+            +   F +D R+GA+  + S  LDRE  + ++V ++A D      D
Sbjct: 484 LPDS-----------ILQYFGVDNRTGAVFVKNSTLLDREVRSLHSVTLQARDS----ED 528

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG--ANSA 186
           +  ST  + + + D ND YP  +  +Y V V E           KI+ATDAD+    NS 
Sbjct: 529 KTGSTE-LEITVTDINDQYPVINRDSYQVFVKEGGDFN-----LKIEATDADMPNTLNSQ 582

Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-----YRLVIRAQDGGSPSRSNTT 241
           I YAI        F+ID  SG ++    LD E + S       L++ A D G+P  S+  
Sbjct: 583 IVYAISPSTYSDNFTIDPNSGVLTNSGNLDREFLDSKLQGRVELIVTATDKGTPPLSSNV 642

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE-LTYTMTDKD 300
            +++NI D+NDN P+F  + +  SV E     Y +  V A D D+      +++++ D  
Sbjct: 643 TVIVNIEDINDNIPQFSNASYTFSVKEGQKGAY-VGSVYAEDLDQTTEFNRISFSIVDGS 701

Query: 301 YTGNVDLPITIDPRSGW-----VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355
            +G+  +    +   G+     V    +LD E+     L + A D     RSA A     
Sbjct: 702 -SGSFIIRSFAEDGRGYRGDIRVDPDVELDYESIRNQTLRIEAADLEQ--RSAEAVVKVN 758

Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSIT 415
                     F P +  V + E+      V   TA D D ++ L YE+     +   S+T
Sbjct: 759 VLDVNDERPEFGPIE-PVSVKENTNNTETVGKFTAYDRDGNHSLLYELESIQCKCNDSMT 817

Query: 416 SQNGRGLITVAQP-------LDFKQERRYVLTVSATDS------GGRSDTAMVQINITDA 462
           S N   L T  +        +D+++  + ++     D          + T ++ INI D 
Sbjct: 818 SCNSFILDTTGEVRVNPNDLVDYEKCDQVLIEAQVVDQFTEKGENNSAKTGLMVINIEDV 877

Query: 463 NNYAPVFENAPYTASVF----EDAPIGTTVLVVSATDSDVGINAQITYSLSS---EISNE 515
           N+ AP F    Y+ SVF    E A  GT+V  V+ATD D G+N Q+ + +++     +N+
Sbjct: 878 NDNAPEFI---YSDSVFVVVSESASKGTSVAGVTATDRDSGLNRQMEFKVTAVQFRDNND 934

Query: 516 AVAHHDQQF-VINPQ-----TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569
                   F  I  Q      G I T + LD +    Y++TVTA D G   LS  T++EI
Sbjct: 935 QTNTMRILFEAITTQQKDSYVGIIQTTEGLDMKLKGKYVVTVTATDTG--GLSTNTELEI 992

Query: 570 SVVD 573
             VD
Sbjct: 993 FTVD 996



 Score =  136 bits (328), Expect = 1e-29
 Identities = 136/499 (27%), Positives = 219/499 (43%), Gaps = 48/499 (9%)

Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383
           LD E + +  L V A D G+    +TAT              F    Y++ + E    G 
Sbjct: 402 LDYEVKQQMILKVVAIDEGESKFRSTATVTISIIDTNDNSPKFPKDTYKLSVPEHASNGM 461

Query: 384 PVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441
            +  +TA D D  +R  + Y +   +    F + ++ G   +  +  LD +    + +T+
Sbjct: 462 VIANITAEDPDTMDRGNIRYRLLPDSILQYFGVDNRTGAVFVKNSTLLDREVRSLHSVTL 521

Query: 442 SATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG-- 499
            A DS  ++ +  ++I +TD N+  PV     Y   V E    G   L + ATD+D+   
Sbjct: 522 QARDSEDKTGSTELEITVTDINDQYPVINRDSYQVFVKEG---GDFNLKIEATDADMPNT 578

Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL-----LTVTAR 554
           +N+QI Y++S          +   F I+P +G +T +  LDRE +   L     L VTA 
Sbjct: 579 LNSQIVYAISPST-------YSDNFTIDPNSGVLTNSGNLDREFLDSKLQGRVELIVTAT 631

Query: 555 DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN- 613
           D G P LS    V +++ D+NDN P F    YT ++ E    G  V  V A D D     
Sbjct: 632 DKGTPPLSSNVTVIVNIEDINDNIPQFSNASYTFSVKEGQK-GAYVGSVYAEDLDQTTEF 690

Query: 614 GRIHYELDPKDREEGSFVIDPAS-------GVIRTNK--ALDRESVATHDLKAVAIDGGT 664
            RI + +   D   GSF+I   +       G IR +    LD ES+    L+  A D   
Sbjct: 691 NRISFSI--VDGSSGSFIIRSFAEDGRGYRGDIRVDPDVELDYESIRNQTLRIEAAD--L 746

Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH- 723
             +S+  +V + + D+ND  P F        + EN+    T+G+  A+D D G +++++ 
Sbjct: 747 EQRSAEAVVKVNVLDVNDERPEF-GPIEPVSVKENTNNTETVGKFTAYDRD-GNHSLLYE 804

Query: 724 ---YSIKGGDDS---NSFSLETRQGSDKAELVTMVDLDY-ESPRKKYELVIRAASPPLWN 776
                 K  D     NSF L+T  G  +     +VD +  +    + ++V +       N
Sbjct: 805 LESIQCKCNDSMTSCNSFILDTT-GEVRVNPNDLVDYEKCDQVLIEAQVVDQFTEKGENN 863

Query: 777 DVRVEILVT---DVNDNAP 792
             +  ++V    DVNDNAP
Sbjct: 864 SAKTGLMVINIEDVNDNAP 882



 Score =  123 bits (296), Expect = 8e-26
 Identities = 142/540 (26%), Positives = 235/540 (43%), Gaps = 41/540 (7%)

Query: 213 KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI 272
           + LDYE  +   L + A D G     +T  + I+I D NDN+P+F    ++ SV E+   
Sbjct: 400 QNLDYEVKQQMILKVVAIDEGESKFRSTATVTISIIDTNDNSPKFPKDTYKLSVPEHASN 459

Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY--TSGQLDRETQA 330
           G  I  + A D D      + Y +       ++     +D R+G V+   S  LDRE ++
Sbjct: 460 GMVIANITAEDPDTMDRGNIRYRL----LPDSILQYFGVDNRTGAVFVKNSTLLDREVRS 515

Query: 331 KYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTA 390
            + + + A D  D  ++ +                     Y+V + E    G   + + A
Sbjct: 516 LHSVTLQARDSED--KTGSTELEITVTDINDQYPVINRDSYQVFVKEG---GDFNLKIEA 570

Query: 391 TDADEDNRLHYEITGGNTRGRFS--ITSQNGRGLITVA-----QPLDFKQERRYVLTVSA 443
           TDAD  N L+ +I    +   +S   T     G++T +     + LD K + R  L V+A
Sbjct: 571 TDADMPNTLNSQIVYAISPSTYSDNFTIDPNSGVLTNSGNLDREFLDSKLQGRVELIVTA 630

Query: 444 TDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501
           TD G    S    V +NI D N+  P F NA YT SV ++   G  V  V A D D    
Sbjct: 631 TDKGTPPLSSNVTVIVNIEDINDNIPQFSNASYTFSV-KEGQKGAYVGSVYAEDLDQTTE 689

Query: 502 -AQITYSLSSEISNEAVAHHDQQFVINPQTG-AITTNKLLDRETMSGYLLTVTARDGGVP 559
             +I++S+    S   +     +     +    +  +  LD E++    L + A D  + 
Sbjct: 690 FNRISFSIVDGSSGSFIIRSFAEDGRGYRGDIRVDPDVELDYESIRNQTLRIEAAD--LE 747

Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619
             S    V+++V+DVND  P F   +   ++ E+     +V +  A D D   N  + YE
Sbjct: 748 QRSAEAVVKVNVLDVNDERPEF-GPIEPVSVKENTNNTETVGKFTAYDRDG--NHSLLYE 804

Query: 620 LDP---KDREE----GSFVIDPASGV-IRTNKALDRESVATHDLKAVAID----GGTPPQ 667
           L+    K  +      SF++D    V +  N  +D E      ++A  +D     G    
Sbjct: 805 LESIQCKCNDSMTSCNSFILDTTGEVRVNPNDLVDYEKCDQVLIEAQVVDQFTEKGENNS 864

Query: 668 SSTVIVHIKIEDINDSPPVF-ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
           + T ++ I IED+ND+ P F  SD +   +SE++  GT++  + A D D G N  + + +
Sbjct: 865 AKTGLMVINIEDVNDNAPEFIYSDSVFVVVSESASKGTSVAGVTATDRDSGLNRQMEFKV 924



 Score =  101 bits (241), Expect = 4e-19
 Identities = 117/420 (27%), Positives = 186/420 (44%), Gaps = 42/420 (10%)

Query: 382 GTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441
           G     + A+D + D  L +E+ G N+ G FS+  + G G + + Q LD +    YV  V
Sbjct: 1   GEVAFVIDASDPENDP-LTFELIGPNS-GFFSV--EQGTGRVFIDQTLDREWIIYYVCGV 56

Query: 442 SATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501
                        + I + +AN+  P+F+ + Y     ED  +G ++    A D D+   
Sbjct: 57  FQIQRD-------LTIFLKEANDNKPIFQQSSYDTKTPEDTAVGASLFTALAEDRDLSNA 109

Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG-YLLTVTARDGGVPS 560
             + YS+   I +  V      F IN  +G +  N  L+  T+S  Y L + A DGG   
Sbjct: 110 GAVRYSIDEVIPSSGV----NLFRIN-ASGVVWLNGSLNYNTLSTFYQLKINATDGGGRC 164

Query: 561 LSDTTDV-------EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613
             + T+         I++VDV D  P+F    Y A++ E++ V  SV  V A D D G+N
Sbjct: 165 FYNETNFWSNVVFSFITIVDVPDLNPMFLGLPYVASVEENSPVNHSVFTVNAFDQDKGIN 224

Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA-THDLKAVAIDGGTPPQ----S 668
             I Y ++     EG F I    GVI     +DRE    T +L   A +          +
Sbjct: 225 DAIIYSIE-GSTTEGLFKISSDDGVISVAGPIDREVTGDTVNLTVKATESKQDVHGVFAN 283

Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
           +TV V I I+D+ND+ P F   C  FY    S      GE+  H      +  ++ ++K 
Sbjct: 284 TTVQVQINIQDVNDNGPEFYK-C-GFYCVNTSHF---TGEVLEHFLG---SISINMTVK- 334

Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVN 788
             D  S S  TR    K  L   + +  ++PR   +L++      +++ V+ E LV+ +N
Sbjct: 335 DPDRVSRSTITRTPEPKVWLRVTLTIFPKTPRT--QLILEGEDKDVFS-VQPESLVSGIN 391



 Score = 90.6 bits (215), Expect = 5e-16
 Identities = 88/319 (27%), Positives = 141/319 (44%), Gaps = 41/319 (12%)

Query: 15  DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
           + ND+ P+F+   Y+    E  + G ++ T  A D+D+     V Y+I     D + P  
Sbjct: 69  EANDNKPIFQQSSYDTKTPEDTAVGASLFTALAEDRDLSNAGAVRYSI-----DEVIPSS 123

Query: 75  AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPV----SDR 129
                        ++FRI+  SG +    SL+   ++  Y + + ATD         ++ 
Sbjct: 124 GV-----------NLFRINA-SGVVWLNGSLNYNTLSTFYQLKINATDGGGRCFYNETNF 171

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
            S+     + I+D  D  P F    Y  SV+E+  V  N  +  + A D D G N AI Y
Sbjct: 172 WSNVVFSFITIVDVPDLNPMFLGLPYVASVEENSPV--NHSVFTVNAFDQDKGINDAIIY 229

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVR-SYRLVIRA----QDGGSPSRSNTTQLL 244
           +I G  T+  F I S  G +S+   +D E    +  L ++A    QD      + T Q+ 
Sbjct: 230 SIEGSTTEGLFKISSDDGVISVAGPIDREVTGDTVNLTVKATESKQDVHGVFANTTVQVQ 289

Query: 245 INIRDVNDNAPRFY--------TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
           INI+DVNDN P FY        TS F   V E+  +G   + +   D D    + +T T 
Sbjct: 290 INIQDVNDNGPEFYKCGFYCVNTSHFTGEVLEHF-LGSISINMTVKDPDRVSRSTITRTP 348

Query: 297 TDKDYTGNVDLPITIDPRS 315
             K +   + + +TI P++
Sbjct: 349 EPKVW---LRVTLTIFPKT 364



 Score = 75.8 bits (178), Expect = 2e-11
 Identities = 67/209 (32%), Positives = 96/209 (45%), Gaps = 19/209 (9%)

Query: 144 NDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI---IGGNTQMQF 200
           NDN P F + +Y     ED +V  +   A   A D D+    A+RY+I   I  +    F
Sbjct: 71  NDNKPIFQQSSYDTKTPEDTAVGASLFTAL--AEDRDLSNAGAVRYSIDEVIPSSGVNLF 128

Query: 201 SIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGGSPSRSNTTQL-------LINIRDVND 252
            I++ SG V L  +L+Y  + + Y+L I A DGG     N T          I I DV D
Sbjct: 129 RINA-SGVVWLNGSLNYNTLSTFYQLKINATDGGGRCFYNETNFWSNVVFSFITIVDVPD 187

Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312
             P F    +  SV EN P+ +S+  V A+D D+G+N  + Y++      G       I 
Sbjct: 188 LNPMFLGLPYVASVEENSPVNHSVFTVNAFDQDKGINDAIIYSIEGSTTEG----LFKIS 243

Query: 313 PRSGWVYTSGQLDRE-TQAKYQLLVTATD 340
              G +  +G +DRE T     L V AT+
Sbjct: 244 SDDGVISVAGPIDREVTGDTVNLTVKATE 272



 Score = 52.4 bits (120), Expect = 2e-04
 Identities = 43/142 (30%), Positives = 63/142 (44%), Gaps = 21/142 (14%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I ++D  D +P+F    Y ASV E +    +V T+ A DQD G N  + Y+IE  T + L
Sbjct: 180 ITIVDVPDLNPMFLGLPYVASVEENSPVNHSVFTVNAFDQDKGINDAIIYSIEGSTTEGL 239

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA-RYTVLVKATDQASPVSDR 129
                              F+I    G +     +DRE       + VKAT+    V   
Sbjct: 240 -------------------FKISSDDGVISVAGPIDREVTGDTVNLTVKATESKQDVHGV 280

Query: 130 LSSTAT-IHVNIIDDNDNYPQF 150
            ++T   + +NI D NDN P+F
Sbjct: 281 FANTTVQVQINIQDVNDNGPEF 302



 Score = 51.2 bits (117), Expect = 4e-04
 Identities = 48/172 (27%), Positives = 70/172 (40%), Gaps = 13/172 (7%)

Query: 11   INVLDCNDHSPVF-EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            IN+ D ND++P F         V E AS GT+V  + ATD+D G N ++E+ +  V    
Sbjct: 872  INIEDVNDNAPEFIYSDSVFVVVSESASKGTSVAGVTATDRDSGLNRQMEFKVTAVQFRD 931

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
             N +             Q   + D   G + T   LD +   +Y V V ATD        
Sbjct: 932  NNDQTNTMRILFEAITTQ---QKDSYVGIIQTTEGLDMKLKGKYVVTVTATDTGG----- 983

Query: 130  LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181
            LS+   + +  +D+        E  +T S  E     D  + A   AT A V
Sbjct: 984  LSTNTELEIFTVDETYKV----ELEFTSSEQEVEQKLDEIINALTAATKAAV 1031


>UniRef50_Q9UN73-2 Cluster: Isoform 2 of Q9UN73 ; n=6; Mammalia|Rep:
           Isoform 2 of Q9UN73 - Homo sapiens (Human)
          Length = 686

 Score =  184 bits (447), Expect = 4e-44
 Identities = 130/419 (31%), Positives = 195/419 (46%), Gaps = 24/419 (5%)

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQ-AYDADEGVNAELTYTMTDKDYTG 303
           + +RD+NDN P F     +  + E+  +  S+  ++ A DAD G N+ LTY ++  +Y G
Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYES-RLPDSVFPLEGASDADVGSNSILTYKLSSSEYFG 179

Query: 304 NVDLPITIDPRSG-WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
            +D+ I  D      +     LDRE    + L +TATDGG P  + T             
Sbjct: 180 -LDVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDN 238

Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYE---ITGGNTRGRFSITSQ 417
              F   +YEV + E+   GT V+ L A+D DE  +  + Y    +        FSI   
Sbjct: 239 APTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRN 298

Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYT 475
            G   I +   LDF+QE  Y + + ATD G    +    V + I D N+  P       +
Sbjct: 299 TGE--IVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLS 356

Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535
             V EDA  GT + ++S  D D G N Q+  SL+  +  + V+     +       ++  
Sbjct: 357 LPVREDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYY-------SLVL 409

Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
           +  LDRE++S Y L VTARDGG PSL  T  + + V D+NDN P F Q  YT  + E+  
Sbjct: 410 DSALDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNP 469

Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPK---DREEGSFV-IDPASGVIRTNKALDRESV 650
            G  +  V A DAD   N  + Y L  +   +R   S++ +   SG +   + LD E +
Sbjct: 470 PGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEEL 528



 Score =  178 bits (433), Expect = 2e-42
 Identities = 130/468 (27%), Positives = 222/468 (47%), Gaps = 21/468 (4%)

Query: 87  QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146
           +D+  ++ ++G L   + +DRE++   +   + +     + DR      + V + D NDN
Sbjct: 72  EDLLEVNLQNGILFVNSRIDREELCGRSA--ECSIHLEVIVDRPLQVFHVDVEVRDINDN 129

Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI-----IGGNTQMQFS 201
            P F  +   V + E  S   + V     A+DADVG+NS + Y +      G + ++  S
Sbjct: 130 PPLFPVEEQRVLIYE--SRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKIN-S 186

Query: 202 IDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261
            D+    + L K+LD E+  ++ L + A DGG P  + T QLL+ + DVNDNAP F  S 
Sbjct: 187 DDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSE 246

Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321
           ++  + EN   G +++R+ A D DEG N  ++Y+         +D   +ID  +G +   
Sbjct: 247 YEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVID-HFSIDRNTGEIVIR 305

Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381
           G LD E +  Y++L+ ATD G PP +   T                     + + ED   
Sbjct: 306 GNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQF 365

Query: 382 GTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL 439
           GT +  ++  D D   + +++  +T  +   +   T +N   L+ +   LD +    Y L
Sbjct: 366 GTVIALISVNDLDSGANGQVNCSLT-PHVPFKLVSTFKNYYSLV-LDSALDRESVSAYEL 423

Query: 440 TVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497
            V+A D G  S   TA + + + D N+ AP F    YT  V E+ P G  +  VSA D+D
Sbjct: 424 VVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDAD 483

Query: 498 VGINAQITYSL-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
              NA ++YSL    +   A++ +     ++ ++G +   + LD E +
Sbjct: 484 AQENALVSYSLVERRVGERALSSY---ISVHAESGKVYALQPLDHEEL 528



 Score =  169 bits (412), Expect = 7e-40
 Identities = 108/343 (31%), Positives = 178/343 (51%), Gaps = 11/343 (3%)

Query: 390 ATDAD--EDNRLHYEITGGNTRGR-FSITSQNGRGL-ITVAQPLDFKQERRYVLTVSATD 445
           A+DAD   ++ L Y+++     G    I S + + + + + + LD ++   + L ++ATD
Sbjct: 157 ASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATD 216

Query: 446 SGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503
            G    T  VQ+ +T  D N+ AP FE + Y   +FE+A  GTTV+ ++A+D D G N  
Sbjct: 217 GGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGA 276

Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD 563
           I+YS +S ++   + H    F I+  TG I     LD E  + Y + + A D G P ++ 
Sbjct: 277 ISYSFNSLVAAMVIDH----FSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAG 332

Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK 623
              V + ++D NDN P       +  + EDA  GT ++ +   D D G NG+++  L P 
Sbjct: 333 HCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLTPH 392

Query: 624 DREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS 683
              +          ++  + ALDRESV+ ++L   A DGG+P   +T  + +++ D+ND+
Sbjct: 393 VPFKLVSTFKNYYSLV-LDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDN 451

Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
            P F     T ++ EN+P G  I  + A D D   NA+V YS+
Sbjct: 452 APAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494



 Score =  163 bits (395), Expect = 8e-38
 Identities = 109/321 (33%), Positives = 160/321 (49%), Gaps = 28/321 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + VLD ND++P FE  +YE  + E A +GTTV+ L A+D+D G N  + Y+   + A   
Sbjct: 230 VTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVA--- 286

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                          V D F ID  +G ++ R +LD E+   Y +L+ ATD+  P    +
Sbjct: 287 -------------AMVIDHFSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHP---PM 330

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           +   T+ V I+D NDN P+ +  + ++ V ED       VIA I   D D GAN  +  +
Sbjct: 331 AGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQF--GTVIALISVNDLDSGANGQVNCS 388

Query: 191 IIGGNTQMQFS-IDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
           +      + F  + +     SLV    LD E V +Y LV+ A+DGGSPS   T  L + +
Sbjct: 389 L---TPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEV 445

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN-VD 306
            D+NDNAP F    +   V EN P G  I  V A DAD   NA ++Y++ ++      + 
Sbjct: 446 ADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALS 505

Query: 307 LPITIDPRSGWVYTSGQLDRE 327
             I++   SG VY    LD E
Sbjct: 506 SYISVHAESGKVYALQPLDHE 526



 Score =  151 bits (366), Expect = 3e-34
 Identities = 114/345 (33%), Positives = 162/345 (46%), Gaps = 17/345 (4%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE--I 512
           V + + D N+  P+F        ++E     +   +  A+D+DVG N+ +TY LSS    
Sbjct: 119 VDVEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYF 178

Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572
             +   + D     N Q G +   K LDRE    + L +TA DGG P L+ T  + ++V+
Sbjct: 179 GLDVKINSDD----NKQIGLLL-KKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVL 233

Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP--KDREEGSF 630
           DVNDN P F+Q  Y   I E+A  GT+V ++ A+D D G NG I Y  +          F
Sbjct: 234 DVNDNAPTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHF 293

Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690
            ID  +G I     LD E    + +   A D G PP +    V ++I D ND+ P     
Sbjct: 294 SIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALT 353

Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750
            L+  + E++  GT I  I  +D D G N  V+ S+        F L      +   LV 
Sbjct: 354 SLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSL---TPHVPFKL-VSTFKNYYSLVL 409

Query: 751 MVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792
              LD ES    YELV+ A    SP LW    + + V D+NDNAP
Sbjct: 410 DSALDRESV-SAYELVVTARDGGSPSLWATASLSVEVADMNDNAP 453



 Score =  116 bits (278), Expect = 1e-23
 Identities = 96/326 (29%), Positives = 145/326 (44%), Gaps = 21/326 (6%)

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
           SV E+A  GT V  ++    D+G+       L   +   A    +    +N Q G +  N
Sbjct: 34  SVPEEAKHGTFVGRIA---QDLGLELA---ELVPRLFRMASKDREDLLEVNLQNGILFVN 87

Query: 537 KLLDRETMSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
             +DRE + G     +   +  V        V++ V D+NDN P+F  +     I E  L
Sbjct: 88  SRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLFPVEEQRVLIYESRL 147

Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI---DPASGVIRTNKALDRESVAT 652
             +     GA+DADVG N  + Y+L   +       I   D     +   K+LDRE    
Sbjct: 148 PDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIGLLLKKSLDREEAPA 207

Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712
           H+L   A DGG P  + TV + + + D+ND+ P FE       I EN+  GTT+  + A 
Sbjct: 208 HNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIRLNAS 267

Query: 713 DPDEGPNAVVHY---SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769
           D DEG N  + Y   S+      + FS++   G    E+V   +LD+E     Y+++I A
Sbjct: 268 DRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG----EIVIRGNLDFEQ-ENLYKILIDA 322

Query: 770 AS---PPLWNDVRVEILVTDVNDNAP 792
                PP+     V + + D NDN P
Sbjct: 323 TDKGHPPMAGHCTVLVRILDKNDNVP 348



 Score = 60.5 bits (140), Expect = 7e-07
 Identities = 57/226 (25%), Positives = 106/226 (46%), Gaps = 16/226 (7%)

Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIH--YELDPKDREEGSFVIDPASGVIRTNKALD 646
           ++ E+A  GT V ++ A D  + L   +   + +  KDRE+    ++  +G++  N  +D
Sbjct: 34  SVPEEAKHGTFVGRI-AQDLGLELAELVPRLFRMASKDRED-LLEVNLQNGILFVNSRID 91

Query: 647 RESVATHDLK-AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
           RE +     + ++ ++           V +++ DIND+PP+F  +     I E+    + 
Sbjct: 92  REELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLFPVEEQRVLIYESRLPDSV 151

Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV---DLDYE-SPRK 761
                A D D G N+++ Y +     S  F L+ +  SD  + + ++    LD E +P  
Sbjct: 152 FPLEGASDADVGSNSILTYKLSS---SEYFGLDVKINSDDNKQIGLLLKKSLDREEAPAH 208

Query: 762 KYELVIR-AASPPLWNDVRVEILVTDVNDNAPVMK--DFQI-IFNN 803
              L       P L   V++ + V DVNDNAP  +  ++++ IF N
Sbjct: 209 NLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFEN 254


>UniRef50_UPI0000E486F2 Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 1139

 Score =  182 bits (443), Expect = 1e-43
 Identities = 166/558 (29%), Positives = 259/558 (46%), Gaps = 35/558 (6%)

Query: 119 ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178
           A  Q+S    R +STA +H+ + D N+  P F    Y  ++ ED  V  N  I +++A D
Sbjct: 163 AIAQSSSGGVRSTSTAEVHIVVQDVNEQPPLFLRGNYAATISEDYPVFSN--IIQVEAHD 220

Query: 179 ADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD------G 232
           +D G N  + Y+        QF+I + +G VSL + LD++Q  SY L + A+D      G
Sbjct: 221 SDSGTNGEVYYSF--RQQTDQFAIHTTTGVVSLTRPLDFDQQSSYTLTVVAKDRGFTPYG 278

Query: 233 GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292
           G P  S   QL I ++ VN ++P       Q +VS N  IG     V   D D GVN E+
Sbjct: 279 GLPLTS-PVQLRIYVQQVNKHSPEIRIEK-QPTVSRNSEIGTVFAVVGVTDEDGGVNGEI 336

Query: 293 -TYTMTDKDYTGNVDLPITIDP-RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350
               + D D  G   +  +  P R         L       + + V A+D G  P+S + 
Sbjct: 337 AALDIIDGDPGGFFRVQPSPSPGRYQLQIARSLLSSSLPHAFNVTVAASDRGLSPKSTSL 396

Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG 410
                          F    +   + E  P  TP +++    A  +    Y IT  +   
Sbjct: 397 VVGVVLDGAMNYEAYFTNDFFNTTINELMPVNTPFLSVAPRSAVGNTGFSYVITDSSL-- 454

Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPV 468
            FSI +    G+++VA  LD +    Y  TV+  ++  +  +DT +V I ++DAN+  P 
Sbjct: 455 PFSIGTHT--GMLSVAFDLDRETTPEYEFTVAVRNAKQQTIADTRVVVI-LSDANDNNPS 511

Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528
           FE   YT  V E+ P  + VLVV A+D D+G N  I+YS++   +  AV      F I+ 
Sbjct: 512 FEEEIYTVEVEENRPAHSQVLVVRASDPDLGENGFISYSIA---NLNAV-----PFTIDH 563

Query: 529 QTGAITTNKLLDRETM-SGYLLTVTARDGGVPSLSDTTDVEI-SVVDVNDNEPVFKQQLY 586
           +TG+I T+K+LD ETM   Y L V A D G P   +   V I +++++NDN P F++   
Sbjct: 564 ETGSINTSKVLDYETMRHQYRLRVRASDWGSPFRREAKAVVIVNLINLNDNRPKFEKINC 623

Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646
              I +    G +++ + A D D     R  Y +   +  +  F I+P SG +  ++ + 
Sbjct: 624 VGAIAKSFPSGRAIALISALDFD---ENRPRYWITSGNVND-LFSINPQSGNLTLSRPVA 679

Query: 647 RESVATHDLKAVAIDGGT 664
                 + L+  A DG T
Sbjct: 680 DSDPLFYSLRIEARDGPT 697



 Score =  179 bits (435), Expect = 1e-42
 Identities = 124/342 (36%), Positives = 178/342 (52%), Gaps = 22/342 (6%)

Query: 462  ANNYAPVFENAPYTA-SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520
            +N + P FE    T+  V EDAP+G TVL V+A D D G N ++ Y++S    N+  +H 
Sbjct: 763  SNVHEPEFETGFRTSVEVPEDAPVGGTVLTVNANDLDHGFNGKLLYAISD--GNDK-SHF 819

Query: 521  DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580
               F    +TG +     LDRET S Y +TV   D G P  +  + + I++ DVNDN P 
Sbjct: 820  QMDF----ETGELKVLMPLDRETQSTYDVTVKISDMGKPQHTRKSPLTITLTDVNDNAPQ 875

Query: 581  FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640
            F  + Y   I EDA VG S   V A+D D G N  + Y +     +  SF ID  +G + 
Sbjct: 876  FDLKQYDVAIPEDAEVGLSFLAVHASDRDEGRNQEVRYSI---ISDSPSFDIDIITGELS 932

Query: 641  TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700
                LDRE+   H+++  A D    P SS+VIV + ++DIND+PP          I E+ 
Sbjct: 933  VAGPLDRETNPVHEIRVQATDLSDSPLSSSVIVRVSLDDINDNPPRCLLPEYKVKIREDL 992

Query: 701  PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760
            P G  +  ++AHDPD  PN  V Y +     S+ FS++T  G+    LV M  LDYE   
Sbjct: 993  PTGAAVLSVQAHDPDNPPNGTVRYRL-DTSGSSKFSIDTDYGT--LRLVEM--LDYE-VT 1046

Query: 761  KKYELVIRAAS---PPLWNDVRVEILVTDVNDN--APVMKDF 797
            + YE+V+       P + +  R+ + V DVN+N  APV  ++
Sbjct: 1047 QLYEIVVAIRDEGIPAMSSTCRIVVEVVDVNENTHAPVFPNY 1088



 Score =  176 bits (429), Expect = 6e-42
 Identities = 140/531 (26%), Positives = 243/531 (45%), Gaps = 45/531 (8%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +N+++ ND+ P FE      ++ +   SG  +  + A D D  +      +  +    ++
Sbjct: 606  VNLINLNDNRPKFEKINCVGAIAKSFPSGRAIALISALDFDENRPRYWITSGNVNDLFSI 665

Query: 71   NPEDAXXXXXXXXXXVQDVF---RIDGRSG-----------ALLTRASLDREKVAR-YTV 115
            NP+               +F   RI+ R G            +   A+   +  AR   V
Sbjct: 666  NPQSGNLTLSRPVADSDPLFYSLRIEARDGPTSVSYMRTNMTITNNANPSPQAHARGLKV 725

Query: 116  LVKATDQASPVSD-----RLSSTATIHV-----NIIDDNDNYPQFSEKTYT-VSVDEDIS 164
              + TD A  + +       S+    H+      +   N + P+F     T V V ED  
Sbjct: 726  TCQETDVAEEIEELYGQLEASNQEVEHLPPNYAELYSSNVHEPEFETGFRTSVEVPEDAP 785

Query: 165  VTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR 224
            V     +  + A D D G N  + YAI  GN +  F +D  +G++ ++  LD E   +Y 
Sbjct: 786  V--GGTVLTVNANDLDHGFNGKLLYAISDGNDKSHFQMDFETGELKVLMPLDRETQSTYD 843

Query: 225  LVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA 284
            + ++  D G P  +  + L I + DVNDNAP+F    +  ++ E+  +G S + V A D 
Sbjct: 844  VTVKISDMGKPQHTRKSPLTITLTDVNDNAPQFDLKQYDVAIPEDAEVGLSFLAVHASDR 903

Query: 285  DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP 344
            DEG N E+ Y++     + ++D+ IT     G +  +G LDRET   +++ V ATD  D 
Sbjct: 904  DEGRNQEVRYSIISDSPSFDIDI-IT-----GELSVAGPLDRETNPVHEIRVQATDLSDS 957

Query: 345  PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYE 402
            P S++                 +  +Y+V++ ED P G  V+++ A D D   +  + Y 
Sbjct: 958  PLSSSVIVRVSLDDINDNPPRCLLPEYKVKIREDLPTGAAVLSVQAHDPDNPPNGTVRYR 1017

Query: 403  I-TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINI 459
            + T G++  +FSI +    G + + + LD++  + Y + V+  D G    S T  + + +
Sbjct: 1018 LDTSGSS--KFSIDTD--YGTLRLVEMLDYEVTQLYEIVVAIRDEGIPAMSSTCRIVVEV 1073

Query: 460  TDA--NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508
             D   N +APVF N   T SV E     T V+ +SA D D+GI+ +++Y++
Sbjct: 1074 VDVNENTHAPVFPNYVLTGSVHEGHINDTEVMTISAADMDMGIDGEVSYTI 1124



 Score =  172 bits (419), Expect = 1e-40
 Identities = 120/373 (32%), Positives = 180/373 (48%), Gaps = 19/373 (5%)

Query: 373  VELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430
            VE+ ED P G  V+T+ A D D   + +L Y I+ GN +  F +  + G   + V  PLD
Sbjct: 778  VEVPEDAPVGGTVLTVNANDLDHGFNGKLLYAISDGNDKSHFQMDFETGE--LKVLMPLD 835

Query: 431  FKQERRYVLTVSATDSGGRSDT--AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
             + +  Y +TV  +D G    T  + + I +TD N+ AP F+   Y  ++ EDA +G + 
Sbjct: 836  RETQSTYDVTVKISDMGKPQHTRKSPLTITLTDVNDNAPQFDLKQYDVAIPEDAEVGLSF 895

Query: 489  LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
            L V A+D D G N ++ YS+ S+            F I+  TG ++    LDRET   + 
Sbjct: 896  LAVHASDRDEGRNQEVRYSIISD---------SPSFDIDIITGELSVAGPLDRETNPVHE 946

Query: 549  LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
            + V A D     LS +  V +S+ D+NDN P      Y   I ED   G +V  V A D 
Sbjct: 947  IRVQATDLSDSPLSSSVIVRVSLDDINDNPPRCLLPEYKVKIREDLPTGAAVLSVQAHDP 1006

Query: 609  DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
            D   NG + Y LD        F ID   G +R  + LD E    +++     D G P  S
Sbjct: 1007 DNPPNGTVRYRLDTSG--SSKFSIDTDYGTLRLVEMLDYEVTQLYEIVVAIRDEGIPAMS 1064

Query: 669  STVIVHIKIEDINDS--PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
            ST  + +++ D+N++   PVF +  LT  + E     T +  I A D D G +  V Y+I
Sbjct: 1065 STCRIVVEVVDVNENTHAPVFPNYVLTGSVHEGHINDTEVMTISAADMDMGIDGEVSYTI 1124

Query: 727  KGGDDSNSFSLET 739
            + G     FS+++
Sbjct: 1125 RDGSGLGRFSIDS 1137



 Score =  161 bits (390), Expect = 3e-37
 Identities = 144/535 (26%), Positives = 240/535 (44%), Gaps = 37/535 (6%)

Query: 223 YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY 282
           Y   I     G    ++T ++ I ++DVN+  P F    +  ++SE+ P+  +I++V+A+
Sbjct: 160 YLTAIAQSSSGGVRSTSTAEVHIVVQDVNEQPPLFLRGNYAATISEDYPVFSNIIQVEAH 219

Query: 283 DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG 342
           D+D G N E+ Y+     +    D    I   +G V  +  LD + Q+ Y L V A D G
Sbjct: 220 DSDSGTNGEVYYS-----FRQQTD-QFAIHTTTGVVSLTRPLDFDQQSSYTLTVVAKDRG 273

Query: 343 DPPRSATATXXXXXXXXXXXXXXFMPGQYEVE----LAEDEPPGTPVVTLTATDAD---E 395
             P                        +  +E    ++ +   GT    +  TD D    
Sbjct: 274 FTPYGGLPLTSPVQLRIYVQQVNKHSPEIRIEKQPTVSRNSEIGTVFAVVGVTDEDGGVN 333

Query: 396 DNRLHYEITGGNTRGRFSI--TSQNGRGLITVAQP-LDFKQERRYVLTVSATDSG--GRS 450
                 +I  G+  G F +  +   GR  + +A+  L       + +TV+A+D G   +S
Sbjct: 334 GEIAALDIIDGDPGGFFRVQPSPSPGRYQLQIARSLLSSSLPHAFNVTVAASDRGLSPKS 393

Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510
            + +V + +  A NY   F N  +  ++ E  P+ T  L V A  S VG N   +Y    
Sbjct: 394 TSLVVGVVLDGAMNYEAYFTNDFFNTTINELMPVNTPFLSV-APRSAVG-NTGFSY---- 447

Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570
                 +      F I   TG ++    LDRET   Y  TV  R+    +++DT  V + 
Sbjct: 448 -----VITDSSLPFSIGTHTGMLSVAFDLDRETTPEYEFTVAVRNAKQQTIADTR-VVVI 501

Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630
           + D NDN P F++++YT  + E+    + V  V A+D D+G NG I Y +   +     F
Sbjct: 502 LSDANDNNPSFEEEIYTVEVEENRPAHSQVLVVRASDPDLGENGFISYSI--ANLNAVPF 559

Query: 631 VIDPASGVIRTNKALDRESVA-THDLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFE 688
            ID  +G I T+K LD E++   + L+  A D G+P  + +  +V + + ++ND+ P FE
Sbjct: 560 TIDHETGSINTSKVLDYETMRHQYRLRVRASDWGSPFRREAKAVVIVNLINLNDNRPKFE 619

Query: 689 SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
                  I+++ P G  I  I A D DE       Y I  G+ ++ FS+  + G+
Sbjct: 620 KINCVGAIAKSFPSGRAIALISALDFDENR---PRYWITSGNVNDLFSINPQSGN 671



 Score =  151 bits (365), Expect = 4e-34
 Identities = 147/571 (25%), Positives = 242/571 (42%), Gaps = 32/571 (5%)

Query: 323 QLDRETQAKYQLLVTATDGGDPPRS-ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381
           +++RE + +Y L   A       RS +TA               F+ G Y   ++ED P 
Sbjct: 150 KVNREVRPEYYLTAIAQSSSGGVRSTSTAEVHIVVQDVNEQPPLFLRGNYAATISEDYPV 209

Query: 382 GTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441
            + ++ + A D+D         +      +F+I +  G  ++++ +PLDF Q+  Y LTV
Sbjct: 210 FSNIIQVEAHDSDSGTNGEVYYSFRQQTDQFAIHTTTG--VVSLTRPLDFDQQSSYTLTV 267

Query: 442 SATDSG-----GRSDTAMVQINI--TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494
            A D G     G   T+ VQ+ I     N ++P         +V  ++ IGT   VV  T
Sbjct: 268 VAKDRGFTPYGGLPLTSPVQLRIYVQQVNKHSPEIR-IEKQPTVSRNSEIGTVFAVVGVT 326

Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT-TNKLLDRETMSGYLLTVTA 553
           D D G+N +I  +    I  +       Q   +P    +     LL       + +TV A
Sbjct: 327 DEDGGVNGEI--AALDIIDGDPGGFFRVQPSPSPGRYQLQIARSLLSSSLPHAFNVTVAA 384

Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613
            D G+   S +  V + +    + E  F    +   I E   V T    V    A VG  
Sbjct: 385 SDRGLSPKSTSLVVGVVLDGAMNYEAYFTNDFFNTTINELMPVNTPFLSVAPRSA-VGNT 443

Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673
           G  +   D        F I   +G++     LDRE+   ++   VA+        +   V
Sbjct: 444 GFSYVITD----SSLPFSIGTHTGMLSVAFDLDRETTPEYEF-TVAVRNAKQQTIADTRV 498

Query: 674 HIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN 733
            + + D ND+ P FE +  T  + EN P  + +  +RA DPD G N  + YSI    ++ 
Sbjct: 499 VVILSDANDNNPSFEEEIYTVEVEENRPAHSQVLVVRASDPDLGENGFISYSI-ANLNAV 557

Query: 734 SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--PPLWNDVRVEILVT--DVND 789
            F+++   GS     V    LDYE+ R +Y L +RA+    P   + +  ++V   ++ND
Sbjct: 558 PFTIDHETGSINTSKV----LDYETMRHQYRLRVRASDWGSPFRREAKAVVIVNLINLND 613

Query: 790 NAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGS 848
           N P  +    +    K  FP G     + A D D  ++ +Y I SGN  +L  +N  +G+
Sbjct: 614 NRPKFEKINCVGAIAKS-FPSGRAIALISALDFD-ENRPRYWITSGNVNDLFSINPQSGN 671

Query: 849 MTLSPQLNTNVPKLATMEVSVTDGVNEIKAM 879
           +TLS  +  + P   ++ +   DG   +  M
Sbjct: 672 LTLSRPVADSDPLFYSLRIEARDGPTSVSYM 702



 Score =  134 bits (323), Expect = 4e-29
 Identities = 91/299 (30%), Positives = 153/299 (51%), Gaps = 29/299 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I + D ND++P F+++QY+ ++ E A  G + L + A+D+D G+N EV Y+I    +D+ 
Sbjct: 864  ITLTDVNDNAPQFDLKQYDVAIPEDAEVGLSFLAVHASDRDEGRNQEVRYSI---ISDSP 920

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            +                  F ID  +G L     LDRE    + + V+ATD +      L
Sbjct: 921  S------------------FDIDIITGELSVAGPLDRETNPVHEIRVQATDLSD---SPL 959

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            SS+  + V++ D NDN P+     Y V + ED+       +  ++A D D   N  +RY 
Sbjct: 960  SSSVIVRVSLDDINDNPPRCLLPEYKVKIREDLPT--GAAVLSVQAHDPDNPPNGTVRYR 1017

Query: 191  IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
            +    +  +FSID+  G + LV+ LDYE  + Y +V+  +D G P+ S+T ++++ + DV
Sbjct: 1018 LDTSGSS-KFSIDTDYGTLRLVEMLDYEVTQLYEIVVAIRDEGIPAMSSTCRIVVEVVDV 1076

Query: 251  NDN--APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            N+N  AP F   +   SV E       ++ + A D D G++ E++YT+ D    G   +
Sbjct: 1077 NENTHAPVFPNYVLTGSVHEGHINDTEVMTISAADMDMGIDGEVSYTIRDGSGLGRFSI 1135



 Score = 93.5 bits (222), Expect = 8e-17
 Identities = 88/302 (29%), Positives = 142/302 (47%), Gaps = 31/302 (10%)

Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGI-----NAQITYSLS-SEISNEAVAHH-- 520
           F  + Y A++ E++PI T +    +T+  +G+     +A + Y+L  S++S+   A    
Sbjct: 71  FTRSIYNATIAENSPIRTFI----STEQKMGVYLPDPSATVRYTLQESDVSDLFSARPEV 126

Query: 521 --DQQFV---INP-QTGAITTNKLLDRETMSGYLLTVTARD--GGVPSLSDTTDVEISVV 572
             D  F+     P +  +   N  ++RE    Y LT  A+   GGV S S T +V I V 
Sbjct: 127 VGDFAFLRIRTRPCRNKSQCPNLKVNREVRPEYYLTAIAQSSSGGVRSTS-TAEVHIVVQ 185

Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632
           DVN+  P+F +  Y A I ED  V +++ QV A D+D G NG ++Y      ++   F I
Sbjct: 186 DVNEQPPLFLRGNYAATISEDYPVFSNIIQVEAHDSDSGTNGEVYYSF---RQQTDQFAI 242

Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGG-TP----PQSSTVIVHIKIEDINDSPPVF 687
              +GV+   + LD +  +++ L  VA D G TP    P +S V + I ++ +N   P  
Sbjct: 243 HTTTGVVSLTRPLDFDQQSSYTLTVVAKDRGFTPYGGLPLTSPVQLRIYVQQVNKHSPEI 302

Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA-VVHYSIKGGDDSNSFSLETRQGSDKA 746
             +     +S NS IGT    +   D D G N  +    I  GD    F ++      + 
Sbjct: 303 RIEKQP-TVSRNSEIGTVFAVVGVTDEDGGVNGEIAALDIIDGDPGGFFRVQPSPSPGRY 361

Query: 747 EL 748
           +L
Sbjct: 362 QL 363



 Score = 81.0 bits (191), Expect = 4e-13
 Identities = 71/234 (30%), Positives = 110/234 (47%), Gaps = 29/234 (12%)

Query: 15  DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
           D ND++P FE + Y   V E   + + VL ++A+D D+G+N  + Y+I  + A       
Sbjct: 504 DANDNNPSFEEEIYTVEVEENRPAHSQVLVVRASDPDLGENGFISYSIANLNAVP----- 558

Query: 75  AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA-RYTVLVKATDQASPVSDRLSST 133
                          F ID  +G++ T   LD E +  +Y + V+A+D  SP   R  + 
Sbjct: 559 ---------------FTIDHETGSINTSKVLDYETMRHQYRLRVRASDWGSPF--RREAK 601

Query: 134 ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG 193
           A + VN+I+ NDN P+F +     ++ +  S      IA I A D D    +  RY I  
Sbjct: 602 AVVIVNLINLNDNRPKFEKINCVGAIAK--SFPSGRAIALISALDFD---ENRPRYWITS 656

Query: 194 GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG-GSPSRSNTTQLLIN 246
           GN    FSI+  SG+++L + +       Y L I A+DG  S S   T   + N
Sbjct: 657 GNVNDLFSINPQSGNLTLSRPVADSDPLFYSLRIEARDGPTSVSYMRTNMTITN 710



 Score = 68.9 bits (161), Expect = 2e-09
 Identities = 50/163 (30%), Positives = 82/163 (50%), Gaps = 16/163 (9%)

Query: 642 NKALDRESVATHDLKAVA-IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700
           N  ++RE    + L A+A    G    +ST  VHI ++D+N+ PP+F        ISE+ 
Sbjct: 148 NLKVNREVRPEYYLTAIAQSSSGGVRSTSTAEVHIVVQDVNEQPPLFLRGNYAATISEDY 207

Query: 701 PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760
           P+ + I ++ AHD D G N  V+YS +    ++ F++ T  G     L   +D D +S  
Sbjct: 208 PVFSNIIQVEAHDSDSGTNGEVYYSFR--QQTDQFAIHTTTG--VVSLTRPLDFDQQS-- 261

Query: 761 KKYELVI----RAASP----PLWNDVRVEILVTDVNDNAPVMK 795
             Y L +    R  +P    PL + V++ I V  VN ++P ++
Sbjct: 262 -SYTLTVVAKDRGFTPYGGLPLTSPVQLRIYVQQVNKHSPEIR 303



 Score = 66.1 bits (154), Expect = 1e-08
 Identities = 59/197 (29%), Positives = 87/197 (44%), Gaps = 27/197 (13%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            ++++ D ND+ P   + +Y+  +RE   +G  VL+++A D D   N  V Y +     DT
Sbjct: 966  RVSLDDINDNPPRCLLPEYKVKIREDLPTGAAVLSVQAHDPDNPPNGTVRYRL-----DT 1020

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                                F ID   G L     LD E    Y ++V   D+  P    
Sbjct: 1021 SGSSK---------------FSIDTDYGTLRLVEMLDYEVTQLYEIVVAIRDEGIPA--- 1062

Query: 130  LSSTATIHVNIIDDNDNY--PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
            +SST  I V ++D N+N   P F     T SV E   + D  V+  I A D D+G +  +
Sbjct: 1063 MSSTCRIVVEVVDVNENTHAPVFPNYVLTGSVHEG-HINDTEVMT-ISAADMDMGIDGEV 1120

Query: 188  RYAIIGGNTQMQFSIDS 204
             Y I  G+   +FSIDS
Sbjct: 1121 SYTIRDGSGLGRFSIDS 1137


>UniRef50_Q4S490 Cluster: Chromosome 1 SCAF14742, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 1 SCAF14742, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 1105

 Score =  182 bits (442), Expect = 2e-43
 Identities = 164/625 (26%), Positives = 275/625 (44%), Gaps = 68/625 (10%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F +  R G L T+  LDRE++ R + L +             +   + V ++D ND+ P+
Sbjct: 46  FSVSARDGVLSTQGRLDREELCRGSDLCEVLLSVLYRRSGAMTCLRVRVEVMDQNDHSPR 105

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209
           F         ++D+ +++              G    I +   G          S   ++
Sbjct: 106 FPR------AEQDLEISEM------------AGLRMRIPFGASG----------SKQAEL 137

Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269
            ++K LD E   S  L++ A D G P RS +T + + I D NDN+P F  S     + E+
Sbjct: 138 VIIKELDREVQESVELILVAWDKGDPPRSGSTSIHVRILDSNDNSPTFEDSSPTLELPED 197

Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329
              G +++R++A D D+G+N E+ Y+++ +     V   + +DP++  V     LD E Q
Sbjct: 198 TARGTTVIRLKATDPDQGLNGEVAYSLS-RHTRPEVQRLLAVDPQTAAVSLKAPLDYEVQ 256

Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM-----PGQYEVELAEDEPPGTP 384
           + Y+++V A D G     A                  +     PG     + E  P  T 
Sbjct: 257 SSYEVVVEARDRGPNAVPAYCKLHIKLLDVNDNAPRILFIWDRPGSPGPTVLEGAPRDTF 316

Query: 385 VVTLTATDAD--EDNRLHYEITGGNTRGRFSITS-QNGRGLITVAQPLDFKQERRYVLTV 441
           +  +   DAD   + ++  EI  G+  G F +   Q+G   I     LD ++   Y +T+
Sbjct: 317 LSLVMVLDADSGRNGQVKAEILDGS--GPFRLKHVQDGSYTIVTNGTLDREKVTHYNITL 374

Query: 442 SATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499
            A D G    S    + +++ D N+ APVF  + Y AS  E    G  VL V A D D+ 
Sbjct: 375 LARDHGDPPLSTLGQLTVHVLDENDNAPVFSTSLYKASFEETNSTGYQVLKVQARDVDLE 434

Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
           ++ +++Y + +    +A  +    F ++P +G +   + LD ET   Y   V A D G P
Sbjct: 435 LSGRVSYFIRNATRAQAATY----FSVHPTSGLVRALRPLDYETSRSYWFLVEAVDQGHP 490

Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQ-----LYTANIMEDALVGTSVSQVG---------- 604
            LS T  V+I + DVNDN PV K+      + + +I  +A  G  V+++G          
Sbjct: 491 PLSSTATVQIEIRDVNDNYPVVKEPAPRRGVASLSIPVNADKGEIVTELGMSTREGRAAF 550

Query: 605 ------ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA-THDLKA 657
                 A DAD GLNG++ Y+L  +      F +D A+G +  N     + +  T  L  
Sbjct: 551 LVSTIQAEDADSGLNGQLTYQL-TRAEPNPLFWLDAATGQLFVNTTNATQLIGQTFRLDI 609

Query: 658 VAIDGGTPPQSSTVIVHIKIEDIND 682
              DGG P  S+ + + +   ++ D
Sbjct: 610 SVSDGGRPSLSTGLTLEVTFINLRD 634



 Score =  176 bits (428), Expect = 8e-42
 Identities = 124/401 (30%), Positives = 193/401 (48%), Gaps = 21/401 (5%)

Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382
           +LDRE Q   +L++ A D GDPPRS + +              F      +EL ED   G
Sbjct: 142 ELDREVQESVELILVAWDKGDPPRSGSTSIHVRILDSNDNSPTFEDSSPTLELPEDTARG 201

Query: 383 TPVVTLTATDADE--DNRLHYEITGGNTRGRFS--ITSQNGRGLITVAQPLDFKQERRYV 438
           T V+ L ATD D+  +  + Y ++  +TR      +        +++  PLD++ +  Y 
Sbjct: 202 TTVIRLKATDPDQGLNGEVAYSLSR-HTRPEVQRLLAVDPQTAAVSLKAPLDYEVQSSYE 260

Query: 439 LTVSATDSGGRSDTAMVQINIT--DANNYAP----VFENAPYTA-SVFEDAPIGTTVLVV 491
           + V A D G  +  A  +++I   D N+ AP    +++       +V E AP  T + +V
Sbjct: 261 VVVEARDRGPNAVPAYCKLHIKLLDVNDNAPRILFIWDRPGSPGPTVLEGAPRDTFLSLV 320

Query: 492 SATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTV 551
              D+D G N Q+   +        + H      +   +  I TN  LDRE ++ Y +T+
Sbjct: 321 MVLDADSGRNGQVKAEILDGSGPFRLKH------VQDGSYTIVTNGTLDREKVTHYNITL 374

Query: 552 TARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG 611
            ARD G P LS    + + V+D NDN PVF   LY A+  E    G  V +V A D D+ 
Sbjct: 375 LARDHGDPPLSTLGQLTVHVLDENDNAPVFSTSLYKASFEETNSTGYQVLKVQARDVDLE 434

Query: 612 LNGRIHYELDPKDREEGS--FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669
           L+GR+ Y +    R + +  F + P SG++R  + LD E+  ++     A+D G PP SS
Sbjct: 435 LSGRVSYFIRNATRAQAATYFSVHPTSGLVRALRPLDYETSRSYWFLVEAVDQGHPPLSS 494

Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENS-PIGTTIGEI 709
           T  V I+I D+ND+ PV +       ++  S P+    GEI
Sbjct: 495 TATVQIEIRDVNDNYPVVKEPAPRRGVASLSIPVNADKGEI 535



 Score =  167 bits (405), Expect = 5e-39
 Identities = 130/417 (31%), Positives = 203/417 (48%), Gaps = 24/417 (5%)

Query: 393 ADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RS 450
           A++D  +  E+ G   R  F  +      L+ + + LD + +    L + A D G   RS
Sbjct: 109 AEQDLEIS-EMAGLRMRIPFGASGSKQAELVIIKE-LDREVQESVELILVAWDKGDPPRS 166

Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510
            +  + + I D+N+ +P FE++  T  + ED   GTTV+ + ATD D G+N ++ YSLS 
Sbjct: 167 GSTSIHVRILDSNDNSPTFEDSSPTLELPEDTARGTTVIRLKATDPDQGLNGEVAYSLSR 226

Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570
               E      +   ++PQT A++    LD E  S Y + V ARD G  ++     + I 
Sbjct: 227 HTRPEV----QRLLAVDPQTAAVSLKAPLDYEVQSSYEVVVEARDRGPNAVPAYCKLHIK 282

Query: 571 VVDVNDNEP--VF---KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE-LDPKD 624
           ++DVNDN P  +F   +       ++E A   T +S V   DAD G NG++  E LD   
Sbjct: 283 LLDVNDNAPRILFIWDRPGSPGPTVLEGAPRDTFLSLVMVLDADSGRNGQVKAEILDGSG 342

Query: 625 REEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP 684
                 V D  S  I TN  LDRE V  +++  +A D G PP S+   + + + D ND+ 
Sbjct: 343 PFRLKHVQD-GSYTIVTNGTLDREKVTHYNITLLARDHGDPPLSTLGQLTVHVLDENDNA 401

Query: 685 PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS---FSLETRQ 741
           PVF +        E +  G  + +++A D D   +  V Y I+    + +   FS+    
Sbjct: 402 PVFSTSLYKASFEETNSTGYQVLKVQARDVDLELSGRVSYFIRNATRAQAATYFSVHPTS 461

Query: 742 GSDKAELVTMVDLDYESPRKKYELV--IRAASPPLWNDVRVEILVTDVNDNAPVMKD 796
           G  +A    +  LDYE+ R  + LV  +    PPL +   V+I + DVNDN PV+K+
Sbjct: 462 GLVRA----LRPLDYETSRSYWFLVEAVDQGHPPLSSTATVQIEIRDVNDNYPVVKE 514



 Score =  166 bits (404), Expect = 7e-39
 Identities = 151/520 (29%), Positives = 224/520 (43%), Gaps = 54/520 (10%)

Query: 95  RSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKT 154
           +   L+    LDRE      +++ A D+  P     S + +IHV I+D NDN P F + +
Sbjct: 133 KQAELVIIKELDREVQESVELILVAWDKGDPPR---SGSTSIHVRILDSNDNSPTFEDSS 189

Query: 155 YTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI---IGGNTQMQFSIDSLSGDVSL 211
            T+ + ED +      + ++KATD D G N  + Y++        Q   ++D  +  VSL
Sbjct: 190 PTLELPEDTA--RGTTVIRLKATDPDQGLNGEVAYSLSRHTRPEVQRLLAVDPQTAAVSL 247

Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE-----SV 266
              LDYE   SY +V+ A+D G  +     +L I + DVNDNAPR      +      +V
Sbjct: 248 KAPLDYEVQSSYEVVVEARDRGPNAVPAYCKLHIKLLDVNDNAPRILFIWDRPGSPGPTV 307

Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326
            E  P    +  V   DAD G N ++   + D   +G   L    D  S  + T+G LDR
Sbjct: 308 LEGAPRDTFLSLVMVLDADSGRNGQVKAEILDG--SGPFRLKHVQDG-SYTIVTNGTLDR 364

Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386
           E    Y + + A D GDPP S                  F    Y+    E    G  V+
Sbjct: 365 EKVTHYNITLLARDHGDPPLSTLGQLTVHVLDENDNAPVFSTSLYKASFEETNSTGYQVL 424

Query: 387 TLTATDADED--NRLHYEI---TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441
            + A D D +   R+ Y I   T       FS+   +  GL+   +PLD++  R Y   V
Sbjct: 425 KVQARDVDLELSGRVSYFIRNATRAQAATYFSVHPTS--GLVRALRPLDYETSRSYWFLV 482

Query: 442 SATDSG--GRSDTAMVQINITDAN-NYAPVFENAPYTASVFEDAPI-------------- 484
            A D G    S TA VQI I D N NY  V E AP         P+              
Sbjct: 483 EAVDQGHPPLSSTATVQIEIRDVNDNYPVVKEPAPRRGVASLSIPVNADKGEIVTELGMS 542

Query: 485 ---GTTVLVVS---ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538
              G    +VS   A D+D G+N Q+TY L+        A  +  F ++  TG +  N  
Sbjct: 543 TREGRAAFLVSTIQAEDADSGLNGQLTYQLTR-------AEPNPLFWLDAATGQLFVNTT 595

Query: 539 LDRETM-SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577
              + +   + L ++  DGG PSLS    +E++ +++ D+
Sbjct: 596 NATQLIGQTFRLDISVSDGGRPSLSTGLTLEVTFINLRDH 635



 Score =  158 bits (383), Expect = 2e-36
 Identities = 107/345 (31%), Positives = 168/345 (48%), Gaps = 24/345 (6%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + +LD ND+SP FE       + E  + GTTV+ LKATD D G N EV Y++   T    
Sbjct: 173 VRILDSNDNSPTFEDSSPTLELPEDTARGTTVIRLKATDPDQGLNGEVAYSLSRHT---- 228

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            PE            VQ +  +D ++ A+  +A LD E  + Y V+V+A D+     + +
Sbjct: 229 RPE------------VQRLLAVDPQTAAVSLKAPLDYEVQSSYEVVVEARDRGP---NAV 273

Query: 131 SSTATIHVNIIDDNDNYPQFS---EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
            +   +H+ ++D NDN P+     ++  +           +  ++ +   DAD G N  +
Sbjct: 274 PAYCKLHIKLLDVNDNAPRILFIWDRPGSPGPTVLEGAPRDTFLSLVMVLDADSGRNGQV 333

Query: 188 RYAIIGGNTQMQFS-IDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           +  I+ G+   +   +   S  +    TLD E+V  Y + + A+D G P  S   QL ++
Sbjct: 334 KAEILDGSGPFRLKHVQDGSYTIVTNGTLDREKVTHYNITLLARDHGDPPLSTLGQLTVH 393

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
           + D NDNAP F TSL++ S  E    GY +++VQA D D  ++  ++Y + +        
Sbjct: 394 VLDENDNAPVFSTSLYKASFEETNSTGYQVLKVQARDVDLELSGRVSYFIRNAT-RAQAA 452

Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
              ++ P SG V     LD ET   Y  LV A D G PP S+TAT
Sbjct: 453 TYFSVHPTSGLVRALRPLDYETSRSYWFLVEAVDQGHPPLSSTAT 497



 Score =  109 bits (263), Expect = 8e-22
 Identities = 111/381 (29%), Positives = 173/381 (45%), Gaps = 59/381 (15%)

Query: 2   SVPFCIHQQINVLDCNDHSP--VFEMQQYEA---SVREGASSGTTVLTLKATDQDIGKNA 56
           +VP      I +LD ND++P  +F   +  +   +V EGA   T +  +   D D G+N 
Sbjct: 272 AVPAYCKLHIKLLDVNDNAPRILFIWDRPGSPGPTVLEGAPRDTFLSLVMVLDADSGRNG 331

Query: 57  EVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVL 116
           +V+  I     D   P             VQD       S  ++T  +LDREKV  Y + 
Sbjct: 332 QVKAEI----LDGSGP--------FRLKHVQD------GSYTIVTNGTLDREKVTHYNIT 373

Query: 117 VKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKA 176
           + A D   P    LS+   + V+++D+NDN P FS   Y  S +E  S T   V+ K++A
Sbjct: 374 LLARDHGDPP---LSTLGQLTVHVLDENDNAPVFSTSLYKASFEETNS-TGYQVL-KVQA 428

Query: 177 TDADVGANSAIRYAIIGGNTQMQ----FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232
            D D+  +  + Y  I   T+ Q    FS+   SG V  ++ LDYE  RSY  ++ A D 
Sbjct: 429 RDVDLELSGRVSY-FIRNATRAQAATYFSVHPTSGLVRALRPLDYETSRSYWFLVEAVDQ 487

Query: 233 GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV-SENVPI------------------- 272
           G P  S+T  + I IRDVNDN P       +  V S ++P+                   
Sbjct: 488 GHPPLSSTATVQIEIRDVNDNYPVVKEPAPRRGVASLSIPVNADKGEIVTELGMSTREGR 547

Query: 273 -GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK 331
             + +  +QA DAD G+N +LTY +T        +    +D  +G ++ +     +   +
Sbjct: 548 AAFLVSTIQAEDADSGLNGQLTYQLT----RAEPNPLFWLDAATGQLFVNTTNATQLIGQ 603

Query: 332 -YQLLVTATDGGDPPRSATAT 351
            ++L ++ +DGG P  S   T
Sbjct: 604 TFRLDISVSDGGRPSLSTGLT 624


>UniRef50_UPI00006A195F Cluster: Cadherin-16 precursor
           (Kidney-specific cadherin) (Ksp-cadherin).; n=4; Xenopus
           tropicalis|Rep: Cadherin-16 precursor (Kidney-specific
           cadherin) (Ksp-cadherin). - Xenopus tropicalis
          Length = 804

 Score =  181 bits (441), Expect = 2e-43
 Identities = 201/719 (27%), Positives = 310/719 (43%), Gaps = 62/719 (8%)

Query: 87  QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146
           +++F +D  SG L      DRE+ A YT+ V        V + LS   TIH+ + D+NDN
Sbjct: 59  EEIFGVDPESGFLYALKPFDRERKASYTLQVTLR---KGVEEILSQMVTIHIMVKDENDN 115

Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA--NSAIRYAII----GGNTQMQF 200
            P F+E T+   V +            + ATD D  +  N+ +RY +I      + +  F
Sbjct: 116 MPVFTENTFYGIVSK--GTKQGVAFMHVNATDLDDSSTPNADLRYKLISRYPARSYENMF 173

Query: 201 SIDSLSGDVSL----VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256
            +D  +G +SL    V +L   +V+ ++L ++ +D G      T+   + I    +    
Sbjct: 174 QVDPKTGSISLTEQGVSSLSKLEVKYFKLEVQVKDFGDEPMGYTSVANLEISVAENTWIA 233

Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316
               L QE+     P   S V+          + EL Y++   D++  V     ID   G
Sbjct: 234 ESPVLLQENQKGGYPRIISEVKWN--------STELHYSLKG-DFSEEV---FRID-EDG 280

Query: 317 WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376
            +Y   +LDRETQA+YQ+ V+A +  D P +                  F    Y VE+ 
Sbjct: 281 KIYIMSELDRETQAEYQIEVSAMNDEDIPYADHLLIVIKVIDENDNTPTFPQDTYHVEVT 340

Query: 377 EDEPPGTPVVTLTATDADEDN----RLHYEITGGNTR--GRFSITSQNGRGLITVAQ-PL 429
           E    GT +V LTATDAD+ N    ++ Y+IT    +    F    +   G +T+    L
Sbjct: 341 ERTTKGTLLVHLTATDADDRNTKNAQIRYKITSQEPKLPKDFLFHLEEHTGHLTLQDAKL 400

Query: 430 DFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNYAPVFENAPYTASVF-EDAPI 484
                ++Y L +SATD G    G S T  V IN+ D N+  PVF    +   +  EDA  
Sbjct: 401 KASIAKKYKLEISATDLGGDPEGLSSTCFVFINVIDVNDSPPVFVKNKFAPFLIPEDAQT 460

Query: 485 GTTVLVVSATDSDVGI-NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
           G  ++ ++ATD D  I N  I + + S   +        Q      T  I   K LD E 
Sbjct: 461 GMLIITLTATDEDEQIENKIIDFYIQSGNEDGTFGITTNQ---EQSTMTIFLEKDLDYEQ 517

Query: 544 MSGYLLTVTARD-----GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
              Y L +T R+     G   S + T  + I VV+VN+  PVF Q+ Y   + E A  G+
Sbjct: 518 TQEYNLIITVRNRAELLGTEYSPTSTAAIHIMVVNVNE-APVFTQKKYEVRVPESAQAGS 576

Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA-THDLKA 657
            +  V A+D    ++  + Y +  ++  +    I   SG I+   +LDRE    T+ ++ 
Sbjct: 577 VILAVEASDP---VSSFLSYSI--RNDSKRCLSIQEHSGKIQLLHSLDREVFEDTYTVQV 631

Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717
           +  + G    S+T  V I I D+ND+ P+   D    Y          I  IRA D D  
Sbjct: 632 LVQEKGDRGLSATADVVIYILDVNDNIPILVGDYSEEYFCTPRRDNQRI-IIRAFDLDSV 690

Query: 718 PN-AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI--RAASPP 773
            N A   +++       S    T      A L   + + Y  PR  Y L+I   + +PP
Sbjct: 691 ENSAPFTFTLSNEPTLQSRWRVTALNGTHAYL--SMGISYLEPRVHYVLIIITDSGTPP 747



 Score =  173 bits (420), Expect = 8e-41
 Identities = 171/628 (27%), Positives = 275/628 (43%), Gaps = 45/628 (7%)

Query: 192 IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251
           + GN +  F +D  SG +  +K  D E+  SY L +  + G     S    + I ++D N
Sbjct: 54  LAGNDEEIFGVDPESGFLYALKPFDRERKASYTLQVTLRKGVEEILSQMVTIHIMVKDEN 113

Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG--VNAELTYTMTDKDYTGNVDLPI 309
           DN P F  + F   VS+    G + + V A D D+    NA+L Y +  +    + +   
Sbjct: 114 DNMPVFTENTFYGIVSKGTKQGVAFMHVNATDLDDSSTPNADLRYKLISRYPARSYENMF 173

Query: 310 TIDPRSGWVYTSGQ----LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
            +DP++G +  + Q    L +     ++L V   D GD P   T+               
Sbjct: 174 QVDPKTGSISLTEQGVSSLSKLEVKYFKLEVQVKDFGDEPMGYTSVANLEISVAENTWIA 233

Query: 366 FMPGQYEVELAEDEPPGTP-VVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLIT 424
             P    V L E++  G P +++    ++ E   LHY + G  +   F I      G I 
Sbjct: 234 ESP----VLLQENQKGGYPRIISEVKWNSTE---LHYSLKGDFSEEVFRIDED---GKIY 283

Query: 425 VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
           +   LD + +  Y + VSA +      +D  ++ I + D N+  P F    Y   V E  
Sbjct: 284 IMSELDRETQAEYQIEVSAMNDEDIPYADHLLIVIKVIDENDNTPTFPQDTYHVEVTERT 343

Query: 483 PIGTTVLVVSATDSD--VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT-TNKLL 539
             GT ++ ++ATD+D     NAQI Y ++S+   E     D  F +   TG +T  +  L
Sbjct: 344 TKGTLLVHLTATDADDRNTKNAQIRYKITSQ---EPKLPKDFLFHLEEHTGHLTLQDAKL 400

Query: 540 DRETMSGYLLTVTARD-GGVP-SLSDTTDVEISVVDVNDNEPVF-KQQLYTANIMEDALV 596
                  Y L ++A D GG P  LS T  V I+V+DVND+ PVF K +     I EDA  
Sbjct: 401 KASIAKKYKLEISATDLGGDPEGLSSTCFVFINVIDVNDSPPVFVKNKFAPFLIPEDAQT 460

Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI----DPASGVIRTNKALDRESVAT 652
           G  +  + ATD D  +  +I         E+G+F I    + ++  I   K LD E    
Sbjct: 461 GMLIITLTATDEDEQIENKIIDFYIQSGNEDGTFGITTNQEQSTMTIFLEKDLDYEQTQE 520

Query: 653 HDL-----KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707
           ++L         + G     +ST  +HI + ++N++ PVF        + E++  G+ I 
Sbjct: 521 YNLIITVRNRAELLGTEYSPTSTAAIHIMVVNVNEA-PVFTQKKYEVRVPESAQAGSVIL 579

Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD-YESPRKKYELV 766
            + A DP    ++ + YSI+  D     S++   G  K +L+  +D + +E       LV
Sbjct: 580 AVEASDP---VSSFLSYSIR-NDSKRCLSIQEHSG--KIQLLHSLDREVFEDTYTVQVLV 633

Query: 767 IRAASPPLWNDVRVEILVTDVNDNAPVM 794
                  L     V I + DVNDN P++
Sbjct: 634 QEKGDRGLSATADVVIYILDVNDNIPIL 661



 Score =  130 bits (313), Expect = 7e-28
 Identities = 164/645 (25%), Positives = 277/645 (42%), Gaps = 57/645 (8%)

Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
           +  GN +    +DP SG++Y     DRE +A Y L VT   G +   S   T        
Sbjct: 53  ELAGNDEEIFGVDPESGFLYALKPFDRERKASYTLQVTLRKGVEEILSQMVTIHIMVKDE 112

Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR----LHYEI----TGGNTRGR 411
                 F    +   +++    G   + + ATD D+ +     L Y++       +    
Sbjct: 113 NDNMPVFTENTFYGIVSKGTKQGVAFMHVNATDLDDSSTPNADLRYKLISRYPARSYENM 172

Query: 412 FSITSQNGRGLITV--AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVF 469
           F +  + G   +T      L   + + + L V   D G   D  M   ++  AN    V 
Sbjct: 173 FQVDPKTGSISLTEQGVSSLSKLEVKYFKLEVQVKDFG---DEPMGYTSV--ANLEISVA 227

Query: 470 ENAPYTAS--VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527
           EN     S  + ++   G    ++S    +   + ++ YSL  + S E        F I+
Sbjct: 228 ENTWIAESPVLLQENQKGGYPRIISEVKWN---STELHYSLKGDFSEEV-------FRID 277

Query: 528 PQTGAITTNKLLDRETMSGYLLTVTA-RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586
            + G I     LDRET + Y + V+A  D  +P  +D   + I V+D NDN P F Q  Y
Sbjct: 278 -EDGKIYIMSELDRETQAEYQIEVSAMNDEDIP-YADHLLIVIKVIDENDNTPTFPQDTY 335

Query: 587 TANIMEDALVGTSVSQVGATDAD--VGLNGRIHYEL---DPKDREEGSFVIDPASGVIRT 641
              + E    GT +  + ATDAD     N +I Y++   +PK  ++  F ++  +G +  
Sbjct: 336 HVEVTERTTKGTLLVHLTATDADDRNTKNAQIRYKITSQEPKLPKDFLFHLEEHTGHLTL 395

Query: 642 NKALDRESVA-THDLKAVAIDGGTPPQ--SSTVIVHIKIEDINDSPPVF-ESDCLTFYIS 697
             A  + S+A  + L+  A D G  P+  SST  V I + D+NDSPPVF ++    F I 
Sbjct: 396 QDAKLKASIAKKYKLEISATDLGGDPEGLSSTCFVFINVIDVNDSPPVFVKNKFAPFLIP 455

Query: 698 ENSPIGTTIGEIRAHDPDEG-PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756
           E++  G  I  + A D DE   N ++ + I+ G++  +F + T Q      +    DLDY
Sbjct: 456 EDAQTGMLIITLTATDEDEQIENKIIDFYIQSGNEDGTFGITTNQEQSTMTIFLEKDLDY 515

Query: 757 ESPRKKYELVI--RAASPPLWND------VRVEILVTDVNDNAPVMKDFQIIFNNYKDCF 808
           E   ++Y L+I  R  +  L  +        + I+V +VN+ APV    +      +   
Sbjct: 516 EQ-TQEYNLIITVRNRAELLGTEYSPTSTAAIHIMVVNVNE-APVFTQKKYEVRVPESAQ 573

Query: 809 PVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNV-PKLATMEV 867
                  V A D  V+  L Y I   ++   + + E +G + L   L+  V     T++V
Sbjct: 574 AGSVILAVEASD-PVSSFLSYSI-RNDSKRCLSIQEHSGKIQLLHSLDREVFEDTYTVQV 631

Query: 868 SVTD-GVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSP 911
            V + G   + A   + + ++    + ++I + + D + E F +P
Sbjct: 632 LVQEKGDRGLSATADVVIYILD---VNDNIPILVGDYSEEYFCTP 673



 Score =  104 bits (250), Expect = 3e-20
 Identities = 122/466 (26%), Positives = 203/466 (43%), Gaps = 50/466 (10%)

Query: 3   VPFCIHQQI--NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD--IGKNAEV 58
           +P+  H  I   V+D ND++P F    Y   V E  + GT ++ L ATD D    KNA++
Sbjct: 308 IPYADHLLIVIKVIDENDNTPTFPQDTYHVEVTERTTKGTLLVHLTATDADDRNTKNAQI 367

Query: 59  EYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLV 117
            Y  ++ + +   P+D              +F ++  +G L L  A L      +Y + +
Sbjct: 368 RY--KITSQEPKLPKDF-------------LFHLEEHTGHLTLQDAKLKASIAKKYKLEI 412

Query: 118 KATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT-VSVDEDISVTDNPVIAKIKA 176
            ATD      + LSST  + +N+ID ND+ P F +  +    + ED       +I  + A
Sbjct: 413 SATDLGGD-PEGLSSTCFVFINVIDVNDSPPVFVKNKFAPFLIPEDAQT--GMLIITLTA 469

Query: 177 TDADVG-ANSAIRYAIIGGNTQMQFSI----DSLSGDVSLVKTLDYEQVRSYRLVIRAQD 231
           TD D    N  I + I  GN    F I    +  +  + L K LDYEQ + Y L+I  ++
Sbjct: 470 TDEDEQIENKIIDFYIQSGNEDGTFGITTNQEQSTMTIFLEKDLDYEQTQEYNLIITVRN 529

Query: 232 -----GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE 286
                G   S ++T  + I + +VN+ AP F    ++  V E+   G  I+ V+A D   
Sbjct: 530 RAELLGTEYSPTSTAAIHIMVVNVNE-APVFTQKKYEVRVPESAQAGSVILAVEASDP-- 586

Query: 287 GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET-QAKYQLLVTATDGGDPP 345
            V++ L+Y++ +     +    ++I   SG +     LDRE  +  Y + V   + GD  
Sbjct: 587 -VSSFLSYSIRN-----DSKRCLSIQEHSGKIQLLHSLDREVFEDTYTVQVLVQEKGDRG 640

Query: 346 RSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DNRLHYEIT 404
            SATA                + G Y  E           + + A D D  +N   +  T
Sbjct: 641 LSATA-DVVIYILDVNDNIPILVGDYSEEYFCTPRRDNQRIIIRAFDLDSVENSAPFTFT 699

Query: 405 GGN---TRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447
             N    + R+ +T+ NG     ++  + + + R + + +  TDSG
Sbjct: 700 LSNEPTLQSRWRVTALNGTHAY-LSMGISYLEPRVHYVLIIITDSG 744



 Score = 93.5 bits (222), Expect = 8e-17
 Identities = 100/392 (25%), Positives = 170/392 (43%), Gaps = 39/392 (9%)

Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
           +I  +   + + E   + ++ F ++P++G +   K  DRE  + Y L VT R G    LS
Sbjct: 41  KIILATDGQYNTELAGNDEEIFGVDPESGFLYALKPFDRERKASYTLQVTLRKGVEEILS 100

Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL--NGRIHYEL 620
               + I V D NDN PVF +  +   + +    G +   V ATD D     N  + Y+L
Sbjct: 101 QMVTIHIMVKDENDNMPVFTENTFYGIVSKGTKQGVAFMHVNATDLDDSSTPNADLRYKL 160

Query: 621 ---DPKDREEGSFVIDPASGVIRTNK----ALDRESVATHDLKAVAIDGGTPPQSSTVIV 673
               P    E  F +DP +G I   +    +L +  V    L+    D G  P   T + 
Sbjct: 161 ISRYPARSYENMFQVDPKTGSISLTEQGVSSLSKLEVKYFKLEVQVKDFGDEPMGYTSVA 220

Query: 674 HIKIEDINDSPPVFESDCLTFYISENSPIG--TTIGEIRAHDPDEGPNAVVHYSIKGGDD 731
           +++I  + ++  + ES  L   + EN   G    I E++ +  +      +HYS+KG   
Sbjct: 221 NLEI-SVAENTWIAESPVL---LQENQKGGYPRIISEVKWNSTE------LHYSLKG--- 267

Query: 732 SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP---PLWNDVRVEILVTDVN 788
              FS E  +  +  ++  M +LD E+ + +Y++ + A +    P  + + + I V D N
Sbjct: 268 --DFSEEVFRIDEDGKIYIMSELDRET-QAEYQIEVSAMNDEDIPYADHLLIVIKVIDEN 324

Query: 789 DNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD----KLQYRILSGN----NANLI 840
           DN P            +          + A DAD  +    +++Y+I S         L 
Sbjct: 325 DNTPTFPQDTYHVEVTERTTKGTLLVHLTATDADDRNTKNAQIRYKITSQEPKLPKDFLF 384

Query: 841 LLNETTGSMTL-SPQLNTNVPKLATMEVSVTD 871
            L E TG +TL   +L  ++ K   +E+S TD
Sbjct: 385 HLEEHTGHLTLQDAKLKASIAKKYKLEISATD 416



 Score = 90.6 bits (215), Expect = 5e-16
 Identities = 90/345 (26%), Positives = 155/345 (44%), Gaps = 29/345 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEAS-VREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           INV+D ND  PVF   ++    + E A +G  ++TL ATD+D     ++E  I      +
Sbjct: 432 INVIDVNDSPPVFVKNKFAPFLIPEDAQTGMLIITLTATDED----EQIENKIIDFYIQS 487

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
            N +               +F              LD E+   Y +++   ++A  +   
Sbjct: 488 GNEDGTFGITTNQEQSTMTIF----------LEKDLDYEQTQEYNLIITVRNRAELLGTE 537

Query: 130 LS--STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
            S  STA IH+ +++ N+  P F++K Y V V E  S     VI  ++A+D     +S +
Sbjct: 538 YSPTSTAAIHIMVVNVNEA-PVFTQKKYEVRVPE--SAQAGSVILAVEASDP---VSSFL 591

Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVR-SYRLVIRAQDGGSPSRSNTTQLLIN 246
            Y+I   +++   SI   SG + L+ +LD E    +Y + +  Q+ G    S T  ++I 
Sbjct: 592 SYSI-RNDSKRCLSIQEHSGKIQLLHSLDREVFEDTYTVQVLVQEKGDRGLSATADVVIY 650

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN-AELTYTMTDKDYTGNV 305
           I DVNDN P       +E           I+ ++A+D D   N A  T+T++++    + 
Sbjct: 651 ILDVNDNIPILVGDYSEEYFCTPRRDNQRII-IRAFDLDSVENSAPFTFTLSNEPTLQSR 709

Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350
                ++    ++ + G    E +  Y L++  TD G PP+S  A
Sbjct: 710 WRVTALNGTHAYL-SMGISYLEPRVHYVLIII-TDSGTPPQSKLA 752


>UniRef50_Q4S1I3 Cluster: Chromosome 6 SCAF14768, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 6
           SCAF14768, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 697

 Score =  180 bits (438), Expect = 5e-43
 Identities = 135/444 (30%), Positives = 219/444 (49%), Gaps = 38/444 (8%)

Query: 378 DEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436
           +E P   V+    +D+D  ++ + Y ++G      F I    G   I + + LD +++  
Sbjct: 18  EEDPTPQVIGQLRSDSDRGESSIRYILSGEGAGDLFQIDESTGE--IWMLRKLDREEKAS 75

Query: 437 YVLTVSATDSGGRSDTAMVQ---INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
           YVL   A +        +     I + D N+  P+F+N PY +S+ E  P+GTTV  V+A
Sbjct: 76  YVLQAQAINRRSSQPEELQSEFIITVQDINDNVPLFQNEPYESSIPEMCPLGTTVARVTA 135

Query: 494 TDSD---VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN-KLLDRETMSGYLL 549
           TD+D    G NA++ YS         +   +  F + P+TG I T+   +DRE    YL+
Sbjct: 136 TDADDPMFGNNAKLIYS---------ILQGEPYFSVEPKTGIIVTSWPNMDREARDQYLV 186

Query: 550 TVTARD--GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
            V A+D  G     S +T V +S+ DVNDN P F+  +Y   + E+A VGT+V ++ A D
Sbjct: 187 VVQAKDMLGLSGGHSSSTTVTVSLTDVNDNGPTFQHHVYAFGVPENAAVGTTVGRIMAED 246

Query: 608 ADVGLNGRIHYELDPKDREEGSFVI--DPAS--GVIRTNKALDRESVATHDLKAVAIDGG 663
            D+G+N ++ Y L+    E G+F+I  DP +  GV+   K LD E+     L A A++  
Sbjct: 247 GDIGINAKMSYSLEDSLEESGTFIIRTDPVTQEGVVLLAKPLDFETKRRFVLAAEAVNDY 306

Query: 664 TPPQ-------SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
              +          + + I +ED+ D PPVF      + + EN  +GT +G + A D D 
Sbjct: 307 PDTRFLPLDKFRDRMTLKIIVEDV-DEPPVFLHPLYEWKVPENVVVGTAVGSVSARDGDA 365

Query: 717 GPNAVVHYSI-KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW 775
             N  V YSI +  D  ++F ++   G+    +V  +D +  +           A   L 
Sbjct: 366 FDNP-VRYSIDRRSDAISAFRIDPNNGT--VTVVQPLDRETSAWHNFSAEAKETAQGRLS 422

Query: 776 NDVRVEILVTDVNDNAP-VMKDFQ 798
           + V++ I V D+NDN P + +D+Q
Sbjct: 423 SSVKLFIKVLDINDNVPRLARDYQ 446



 Score =  173 bits (420), Expect = 8e-41
 Identities = 148/482 (30%), Positives = 222/482 (46%), Gaps = 34/482 (7%)

Query: 283 DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG- 341
           D+D G  + + Y ++ +   G  DL   ID  +G ++   +LDRE +A Y L   A +  
Sbjct: 32  DSDRG-ESSIRYILSGE---GAGDL-FQIDESTGEIWMLRKLDREEKASYVLQAQAINRR 86

Query: 342 GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-----D 396
              P    +               F    YE  + E  P GT V  +TATDAD+     +
Sbjct: 87  SSQPEELQSEFIITVQDINDNVPLFQNEPYESSIPEMCPLGTTVARVTATDADDPMFGNN 146

Query: 397 NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD----SGGRSDT 452
            +L Y I  G     FS+  + G  ++T    +D +   +Y++ V A D    SGG S +
Sbjct: 147 AKLIYSILQGEPY--FSVEPKTGI-IVTSWPNMDREARDQYLVVVQAKDMLGLSGGHSSS 203

Query: 453 AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512
             V +++TD N+  P F++  Y   V E+A +GTTV  + A D D+GINA+++YSL   +
Sbjct: 204 TTVTVSLTDVNDNGPTFQHHVYAFGVPENAAVGTTVGRIMAEDGDIGINAKMSYSLEDSL 263

Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA-------RDGGVPSLSDTT 565
                       V   Q G +   K LD ET   ++L   A       R   +    D  
Sbjct: 264 EESGTFIIRTDPVT--QEGVVLLAKPLDFETKRRFVLAAEAVNDYPDTRFLPLDKFRDRM 321

Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625
            ++I V DV D  PVF   LY   + E+ +VGT+V  V A D D   +  + Y +D +  
Sbjct: 322 TLKIIVEDV-DEPPVFLHPLYEWKVPENVVVGTAVGSVSARDGDA-FDNPVRYSIDRRSD 379

Query: 626 EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685
              +F IDP +G +   + LDRE+ A H+  A A +      SS+V + IK+ DIND+ P
Sbjct: 380 AISAFRIDPNNGTVTVVQPLDRETSAWHNFSAEAKETAQGRLSSSVKLFIKVLDINDNVP 439

Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN---SFSLETRQG 742
               D    YI E +  G  +  I A DPDE P    H+      D +   +F+L   QG
Sbjct: 440 RLARDYQP-YICEGTQPGEPVQLISAVDPDE-PVEGHHFYFSMVPDRHINPNFTLRDNQG 497

Query: 743 SD 744
            +
Sbjct: 498 PE 499



 Score =  158 bits (384), Expect = 2e-36
 Identities = 133/470 (28%), Positives = 223/470 (47%), Gaps = 38/470 (8%)

Query: 170 VIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA 229
           VI ++++ D+D G  S+IRY + G      F ID  +G++ +++ LD E+  SY L  +A
Sbjct: 25  VIGQLRS-DSDRG-ESSIRYILSGEGAGDLFQIDESTGEIWMLRKLDREEKASYVLQAQA 82

Query: 230 -QDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE-- 286
                S      ++ +I ++D+NDN P F    ++ S+ E  P+G ++ RV A DAD+  
Sbjct: 83  INRRSSQPEELQSEFIITVQDINDNVPLFQNEPYESSIPEMCPLGTTVARVTATDADDPM 142

Query: 287 -GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS-GQLDRETQAKYQLLVTATD--GG 342
            G NA+L Y++   +         +++P++G + TS   +DRE + +Y ++V A D  G 
Sbjct: 143 FGNNAKLIYSILQGEPY------FSVEPKTGIIVTSWPNMDREARDQYLVVVQAKDMLGL 196

Query: 343 DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLH 400
               S++ T              F    Y   + E+   GT V  + A D D   + ++ 
Sbjct: 197 SGGHSSSTTVTVSLTDVNDNGPTFQHHVYAFGVPENAAVGTTVGRIMAEDGDIGINAKMS 256

Query: 401 YEITGG-NTRGRFSITSQ--NGRGLITVAQPLDFKQERRYVLTVSATDSGGRS------- 450
           Y +       G F I +      G++ +A+PLDF+ +RR+VL   A +    +       
Sbjct: 257 YSLEDSLEESGTFIIRTDPVTQEGVVLLAKPLDFETKRRFVLAAEAVNDYPDTRFLPLDK 316

Query: 451 --DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508
             D   ++I + D +   PVF +  Y   V E+  +GT V  VSA D D   N  + YS+
Sbjct: 317 FRDRMTLKIIVEDVDE-PPVFLHPLYEWKVPENVVVGTAVGSVSARDGDAFDN-PVRYSI 374

Query: 509 SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568
                ++A++     F I+P  G +T  + LDRET + +  +  A++     LS +  + 
Sbjct: 375 DRR--SDAIS----AFRIDPNNGTVTVVQPLDRETSAWHNFSAEAKETAQGRLSSSVKLF 428

Query: 569 ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618
           I V+D+NDN P   +  Y   I E    G  V  + A D D  + G   Y
Sbjct: 429 IKVLDINDNVPRLARD-YQPYICEGTQPGEPVQLISAVDPDEPVEGHHFY 477



 Score =  143 bits (347), Expect = 5e-32
 Identities = 122/436 (27%), Positives = 200/436 (45%), Gaps = 26/436 (5%)

Query: 88  DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
           D+F+ID  +G +     LDRE+ A Y +  +A ++ S   + L S   I V   D NDN 
Sbjct: 51  DLFQIDESTGEIWMLRKLDREEKASYVLQAQAINRRSSQPEELQSEFIITVQ--DINDNV 108

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD---VGANSAIRYAIIGGNTQMQFSIDS 204
           P F  + Y  S+ E   +     +A++ ATDAD    G N+ + Y+I+ G  +  FS++ 
Sbjct: 109 PLFQNEPYESSIPEMCPL--GTTVARVTATDADDPMFGNNAKLIYSILQG--EPYFSVEP 164

Query: 205 LSGD-VSLVKTLDYEQVRSYRLVIRAQD--GGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261
            +G  V+    +D E    Y +V++A+D  G S   S++T + +++ DVNDN P F   +
Sbjct: 165 KTGIIVTSWPNMDREARDQYLVVVQAKDMLGLSGGHSSSTTVTVSLTDVNDNGPTFQHHV 224

Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK-DYTGNVDLPITIDPRSGWVYT 320
           +   V EN  +G ++ R+ A D D G+NA+++Y++ D  + +G   +      + G V  
Sbjct: 225 YAFGVPENAAVGTTVGRIMAEDGDIGINAKMSYSLEDSLEESGTFIIRTDPVTQEGVVLL 284

Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX------XFMPGQYEVE 374
           +  LD ET+ ++ L   A +     R                         F+   YE +
Sbjct: 285 AKPLDFETKRRFVLAAEAVNDYPDTRFLPLDKFRDRMTLKIIVEDVDEPPVFLHPLYEWK 344

Query: 375 LAEDEPPGTPVVTLTATDADE-DNRLHYEI-TGGNTRGRFSITSQNGRGLITVAQPLDFK 432
           + E+   GT V +++A D D  DN + Y I    +    F I   N  G +TV QPLD +
Sbjct: 345 VPENVVVGTAVGSVSARDGDAFDNPVRYSIDRRSDAISAFRIDPNN--GTVTVVQPLDRE 402

Query: 433 QERRYVLTVSA--TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
               +  +  A  T  G  S +  + I + D N+  P      Y   + E    G  V +
Sbjct: 403 TSAWHNFSAEAKETAQGRLSSSVKLFIKVLDINDNVPRLAR-DYQPYICEGTQPGEPVQL 461

Query: 491 VSATDSDVGINAQITY 506
           +SA D D  +     Y
Sbjct: 462 ISAVDPDEPVEGHHFY 477



 Score =  120 bits (288), Expect = 8e-25
 Identities = 115/407 (28%), Positives = 180/407 (44%), Gaps = 46/407 (11%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVTA 67
           I V D ND+ P+F+ + YE+S+ E    GTTV  + ATD D    G NA++ Y+I     
Sbjct: 99  ITVQDINDNVPLFQNEPYESSIPEMCPLGTTVARVTATDADDPMFGNNAKLIYSI----- 153

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR-ASLDREKVARYTVLVKATDQASPV 126
             L  E                F ++ ++G ++T   ++DRE   +Y V+V+A D    +
Sbjct: 154 --LQGE--------------PYFSVEPKTGIIVTSWPNMDREARDQYLVVVQAKDMLG-L 196

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
           S   SS+ T+ V++ D NDN P F    Y   V E+ +V     + +I A D D+G N+ 
Sbjct: 197 SGGHSSSTTVTVSLTDVNDNGPTFQHHVYAFGVPENAAV--GTTVGRIMAEDGDIGINAK 254

Query: 187 IRYAI-----IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR---- 237
           + Y++       G   ++    +  G V L K LD+E  R + L   A +    +R    
Sbjct: 255 MSYSLEDSLEESGTFIIRTDPVTQEGVVLLAKPLDFETKRRFVLAAEAVNDYPDTRFLPL 314

Query: 238 ---SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294
               +   L I + DV D  P F   L++  V ENV +G ++  V A D D   N  + Y
Sbjct: 315 DKFRDRMTLKIIVEDV-DEPPVFLHPLYEWKVPENVVVGTAVGSVSARDGDAFDN-PVRY 372

Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354
           ++   D   +      IDP +G V     LDRET A +     A +     R +++    
Sbjct: 373 SI---DRRSDAISAFRIDPNNGTVTVVQPLDRETSAWHNFSAEAKETAQ-GRLSSSVKLF 428

Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHY 401
                       +   Y+  + E   PG PV  ++A D DE    H+
Sbjct: 429 IKVLDINDNVPRLARDYQPYICEGTQPGEPVQLISAVDPDEPVEGHH 475



 Score = 95.9 bits (228), Expect = 1e-17
 Identities = 79/289 (27%), Positives = 128/289 (44%), Gaps = 24/289 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           +++ D ND+ P F+   Y   V E A+ GTTV  + A D DIG NA++ Y++E    D+L
Sbjct: 208 VSLTDVNDNGPTFQHHVYAFGVPENAAVGTTVGRIMAEDGDIGINAKMSYSLE----DSL 263

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS--- 127
             E++           Q+        G +L    LD E   R+ +  +A +         
Sbjct: 264 --EESGTFIIRTDPVTQE--------GVVLLAKPLDFETKRRFVLAAEAVNDYPDTRFLP 313

Query: 128 -DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
            D+     T+ + I++D D  P F    Y   V E++ V     +  + A D D   N  
Sbjct: 314 LDKFRDRMTLKI-IVEDVDEPPVFLHPLYEWKVPENVVV--GTAVGSVSARDGDAFDN-P 369

Query: 187 IRYAIIGGNTQMQ-FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
           +RY+I   +  +  F ID  +G V++V+ LD E    +     A++      S++ +L I
Sbjct: 370 VRYSIDRRSDAISAFRIDPNNGTVTVVQPLDRETSAWHNFSAEAKETAQGRLSSSVKLFI 429

Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294
            + D+NDN PR     +Q  + E    G  +  + A D DE V     Y
Sbjct: 430 KVLDINDNVPRLARD-YQPYICEGTQPGEPVQLISAVDPDEPVEGHHFY 477



 Score = 79.4 bits (187), Expect = 1e-12
 Identities = 69/227 (30%), Positives = 114/227 (50%), Gaps = 17/227 (7%)

Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG-GT 664
           +D+D G    I Y L  +   +  F ID ++G I   + LDRE  A++ L+A AI+   +
Sbjct: 31  SDSDRG-ESSIRYILSGEGAGD-LFQIDESTGEIWMLRKLDREEKASYVLQAQAINRRSS 88

Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE---GPNAV 721
            P+       I ++DIND+ P+F+++     I E  P+GTT+  + A D D+   G NA 
Sbjct: 89  QPEELQSEFIITVQDINDNVPLFQNEPYESSIPEMCPLGTTVARVTATDADDPMFGNNAK 148

Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-----SPPLWN 776
           + YSI  G+    FS+E + G     + +  ++D E+ R +Y +V++A      S    +
Sbjct: 149 LIYSILQGEPY--FSVEPKTG---IIVTSWPNMDREA-RDQYLVVVQAKDMLGLSGGHSS 202

Query: 777 DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV 823
              V + +TDVNDN P  +     F   ++       GR+ A D D+
Sbjct: 203 STTVTVSLTDVNDNGPTFQHHVYAFGVPENAAVGTTVGRIMAEDGDI 249


>UniRef50_P55288 Cluster: Cadherin-11 precursor; n=28;
           Tetrapoda|Rep: Cadherin-11 precursor - Mus musculus
           (Mouse)
          Length = 796

 Score =  179 bits (436), Expect = 9e-43
 Identities = 157/540 (29%), Positives = 248/540 (45%), Gaps = 47/540 (8%)

Query: 168 NPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVI 227
           +PV+     +D D G  + I+Y + G      F ID  SG++   KTLD E+   Y L+ 
Sbjct: 70  DPVLVGRLHSDIDSGDGN-IKYILSGEGAGTIFVIDDKSGNIHATKTLDREERAQYTLMA 128

Query: 228 RAQD-GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE 286
           +A D   +      ++ ++ ++D+NDN P F   ++  +V E   +G S+++V A DAD+
Sbjct: 129 QAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHEIYHANVPERSNVGTSVIQVTASDADD 188

Query: 287 ---GVNAELTYTMTD-KDYTGNVDLPITIDPRSGWVYTS-GQLDRETQAKYQLLVTATDG 341
              G +A+L Y++ + + Y        +++ ++G + T+   +DRE + +Y +++ A D 
Sbjct: 189 PTYGNSAKLVYSILEGQPY-------FSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDM 241

Query: 342 GD--PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDN 397
           G      S T                F    Y++ ++E   PG  V  + A D D  E+ 
Sbjct: 242 GGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENG 301

Query: 398 RLHYEITGGNTRGRFSITS--QNGRGLITVAQPLDFKQERRYVLTVSATD---------S 446
            + Y I  G+    F IT+  +   G++ + +P+DF+ +R Y L + A +         +
Sbjct: 302 LVTYNIVDGDGIELFEITTDYETQDGVVKLKKPVDFETKRAYSLKIEAANVHIDPKFISN 361

Query: 447 GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506
           G   DT  V+I++ DA+   P+F    Y   V E+A  GT V  V A D D   N+ I Y
Sbjct: 362 GPFKDTVTVKISVEDADE-PPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAA-NSPIRY 419

Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566
           S+            D+ F INP+ G I T K LDRE  +   ++V A +           
Sbjct: 420 SIDRH------TDLDRFFTINPEDGFIKTTKPLDREETAWLNISVFAAEIHNRHQETKVP 473

Query: 567 VEISVVDVNDNEPVFKQQLYTANIMED----ALVGTSVSQVGATDADVGLNG-RIHYELD 621
           V I V+DVNDN P F    Y   I E     AL    +  V A D D   NG R  + L 
Sbjct: 474 VAIRVLDVNDNAPKFAAP-YEGFICESDHPKALSNQPIVTVSADDQDDTANGPRFIFSLP 532

Query: 622 PKDREEGSFVI----DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
           P+     +F +    D  +GV        R+    + L  V  DGG PP SST  + IK+
Sbjct: 533 PEIMHNPNFTVRDNRDNTAGVYARRGGFSRQKQDFYLLPIVISDGGIPPMSSTNTLTIKV 592



 Score =  167 bits (406), Expect = 4e-39
 Identities = 150/513 (29%), Positives = 237/513 (46%), Gaps = 40/513 (7%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           +F ID +SG +    +LDRE+ A+YT++ +A D+ +  +  L   +   V + D NDN P
Sbjct: 100 IFVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDT--NRPLEPPSEFIVKVQDINDNPP 157

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDAD---VGANSAIRYAIIGGNTQMQFSIDSL 205
           +F  + Y  +V E  +V  +  + ++ A+DAD    G ++ + Y+I+ G  Q  FS+++ 
Sbjct: 158 EFLHEIYHANVPERSNVGTS--VIQVTASDADDPTYGNSAKLVYSILEG--QPYFSVEAQ 213

Query: 206 SGDV-SLVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQLLINIRDVNDNAPRFYTSLF 262
           +G + + +  +D E    Y +VI+A+D G      S TT++ I + DVNDN P+F  S++
Sbjct: 214 TGIIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVY 273

Query: 263 QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322
           Q SVSE    G  + RV+A D D G N  +TY + D D     ++    + + G V    
Sbjct: 274 QMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVDGDGIELFEITTDYETQDGVVKLKK 333

Query: 323 QLDRETQAKYQLLVTATDGGDPPRSAT------ATXXXXXXXXXXXXXXFMPGQYEVELA 376
            +D ET+  Y L + A +    P+  +                      F+   Y  E+ 
Sbjct: 334 PVDFETKRAYSLKIEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQ 393

Query: 377 EDEPPGTPVVTLTATDADEDNR-LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435
           E+   GT V  + A D D  N  + Y I       RF  T     G I   +PLD ++  
Sbjct: 394 ENAAAGTVVGRVHAKDPDAANSPIRYSIDRHTDLDRF-FTINPEDGFIKTTKPLDREETA 452

Query: 436 RYVLTVSATDSGGR-SDTAM-VQINITDANNYAPVFENAPYTASVFE-DAPIGTT---VL 489
              ++V A +   R  +T + V I + D N+ AP F  APY   + E D P   +   ++
Sbjct: 453 WLNISVFAAEIHNRHQETKVPVAIRVLDVNDNAPKFA-APYEGFICESDHPKALSNQPIV 511

Query: 490 VVSATDSDVGINA-QITYSLSSEISNEAVAHHDQQFVINPQ----TGAITTNKLLDRETM 544
            VSA D D   N  +  +SL  EI       H+  F +        G         R+  
Sbjct: 512 TVSADDQDDTANGPRFIFSLPPEIM------HNPNFTVRDNRDNTAGVYARRGGFSRQKQ 565

Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISV--VDVN 575
             YLL +   DGG+P +S T  + I V   DVN
Sbjct: 566 DFYLLPIVISDGGIPPMSSTNTLTIKVCGCDVN 598



 Score =  156 bits (378), Expect = 9e-36
 Identities = 128/430 (29%), Positives = 190/430 (44%), Gaps = 30/430 (6%)

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPPRSATATXXXXXXXXXXXXXXFMPG 369
           ID +SG ++ +  LDRE +A+Y L+  A D   + P    +               F+  
Sbjct: 103 IDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHE 162

Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDN-----RLHYEITGGNTRGRFSITSQNGRGLIT 424
            Y   + E    GT V+ +TA+DAD+       +L Y I  G     FS+ +Q G  +I 
Sbjct: 163 IYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPY--FSVEAQTG--IIR 218

Query: 425 VAQP-LDFKQERRYVLTVSATDSGGR----SDTAMVQINITDANNYAPVFENAPYTASVF 479
            A P +D + +  Y + + A D GG     S T  V I +TD N+  P F  + Y  SV 
Sbjct: 219 TALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVS 278

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           E A  G  V  V A D D+G N  +TY++   +  + +   +       Q G +   K +
Sbjct: 279 EAAVPGEEVGRVKAKDPDIGENGLVTYNI---VDGDGIELFEITTDYETQDGVVKLKKPV 335

Query: 540 DRETMSGYLLTVTARDGGVPS-------LSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592
           D ET   Y L + A +  +           DT  V+ISV D  D  P+F    Y   + E
Sbjct: 336 DFETKRAYSLKIEAANVHIDPKFISNGPFKDTVTVKISVEDA-DEPPMFLAPSYIHEVQE 394

Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652
           +A  GT V +V A D D   N  I Y +D     +  F I+P  G I+T K LDRE  A 
Sbjct: 395 NAAAGTVVGRVHAKDPDAA-NSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAW 453

Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT---IGEI 709
            ++   A +     Q + V V I++ D+ND+ P F +    F    + P   +   I  +
Sbjct: 454 LNISVFAAEIHNRHQETKVPVAIRVLDVNDNAPKFAAPYEGFICESDHPKALSNQPIVTV 513

Query: 710 RAHDPDEGPN 719
            A D D+  N
Sbjct: 514 SADDQDDTAN 523



 Score =  148 bits (359), Expect = 2e-33
 Identities = 130/432 (30%), Positives = 198/432 (45%), Gaps = 34/432 (7%)

Query: 381 PGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL 439
           P   +V    +D D  D  + Y ++G      F I  ++G   I   + LD ++  +Y L
Sbjct: 69  PDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGN--IHATKTLDREERAQYTL 126

Query: 440 TVSATDSGGR---SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496
              A D          +   + + D N+  P F +  Y A+V E + +GT+V+ V+A+D+
Sbjct: 127 MAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHEIYHANVPERSNVGTSVIQVTASDA 186

Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN-KLLDRETMSGYLLTVTARD 555
           D       TY  S+++   ++      F +  QTG I T    +DRE    Y + + A+D
Sbjct: 187 D-----DPTYGNSAKLVY-SILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKD 240

Query: 556 --GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613
             G +  LS TT V I++ DVNDN P F Q +Y  ++ E A+ G  V +V A D D+G N
Sbjct: 241 MGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGEN 300

Query: 614 GRIHYEL---DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ--- 667
           G + Y +   D  +  E +   +   GV++  K +D E+   + LK  A +    P+   
Sbjct: 301 GLVTYNIVDGDGIELFEITTDYETQDGVVKLKKPVDFETKRAYSLKIEAANVHIDPKFIS 360

Query: 668 ----SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
                 TV V I +ED  D PP+F +      + EN+  GT +G + A DPD   N+ + 
Sbjct: 361 NGPFKDTVTVKISVEDA-DEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPD-AANSPIR 418

Query: 724 YSI-KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND--VRV 780
           YSI +  D    F++    G  K    T   LD E        V  A       +  V V
Sbjct: 419 YSIDRHTDLDRFFTINPEDGFIK----TTKPLDREETAWLNISVFAAEIHNRHQETKVPV 474

Query: 781 EILVTDVNDNAP 792
            I V DVNDNAP
Sbjct: 475 AIRVLDVNDNAP 486



 Score =  124 bits (300), Expect = 3e-26
 Identities = 102/324 (31%), Positives = 152/324 (46%), Gaps = 19/324 (5%)

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTA--RDGGVPSLSDTTDVEISVVDVNDNEPVF 581
           FVI+ ++G I   K LDRE  + Y L   A  RD   P L   ++  + V D+NDN P F
Sbjct: 101 FVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRP-LEPPSEFIVKVQDINDNPPEF 159

Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641
             ++Y AN+ E + VGTSV QV A+DAD    G     +      +  F ++  +G+IRT
Sbjct: 160 LHEIYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRT 219

Query: 642 NKA-LDRESVATHDLKAVAID--GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698
               +DRE+   + +   A D  G     S T  V I + D+ND+PP F        +SE
Sbjct: 220 ALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSE 279

Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758
            +  G  +G ++A DPD G N +V Y+I  GD    F + T   +    +     +D+E+
Sbjct: 280 AAVPGEEVGRVKAKDPDIGENGLVTYNIVDGDGIELFEITTDYETQDGVVKLKKPVDFET 339

Query: 759 PRKKYELVIRAA----------SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCF 808
            ++ Y L I AA          + P  + V V+I V D  D  P+      I    ++  
Sbjct: 340 -KRAYSLKIEAANVHIDPKFISNGPFKDTVTVKISVEDA-DEPPMFLAPSYIHEVQENAA 397

Query: 809 PVGPFGRVPAYDADVTDK-LQYRI 831
                GRV A D D  +  ++Y I
Sbjct: 398 AGTVVGRVHAKDPDAANSPIRYSI 421



 Score =  122 bits (294), Expect = 1e-25
 Identities = 109/405 (26%), Positives = 181/405 (44%), Gaps = 51/405 (12%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVTA 67
           + V D ND+ P F  + Y A+V E ++ GT+V+ + A+D D    G +A++ Y+I     
Sbjct: 147 VKVQDINDNPPEFLHEIYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSI----- 201

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR-ASLDREKVARYTVLVKATDQASPV 126
                              Q  F ++ ++G + T   ++DRE    Y V+++A D    +
Sbjct: 202 ----------------LEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGHM 245

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
              LS T  + + + D NDN P+F +  Y +SV E  +      + ++KA D D+G N  
Sbjct: 246 GG-LSGTTKVTITLTDVNDNPPKFPQSVYQMSVSE--AAVPGEEVGRVKAKDPDIGENGL 302

Query: 187 IRYAIIGGNTQMQFSI----DSLSGDVSLVKTLDYEQVRSYRLVIRAQD--------GGS 234
           + Y I+ G+    F I    ++  G V L K +D+E  R+Y L I A +           
Sbjct: 303 VTYNIVDGDGIELFEITTDYETQDGVVKLKKPVDFETKRAYSLKIEAANVHIDPKFISNG 362

Query: 235 PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294
           P + +T  + I++ D  D  P F    +   V EN   G  + RV A D D   N+ + Y
Sbjct: 363 PFK-DTVTVKISVEDA-DEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPD-AANSPIRY 419

Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354
           ++   D   ++D   TI+P  G++ T+  LDRE  A   + V A +  +  +        
Sbjct: 420 SI---DRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNISVFAAEIHNRHQETKVPVAI 476

Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPP----GTPVVTLTATDADE 395
                      F    YE  + E + P      P+VT++A D D+
Sbjct: 477 RVLDVNDNAPKF-AAPYEGFICESDHPKALSNQPIVTVSADDQDD 520



 Score =  101 bits (241), Expect = 4e-19
 Identities = 97/352 (27%), Positives = 146/352 (41%), Gaps = 31/352 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I + D ND+ P F    Y+ SV E A  G  V  +KA D DIG+N  V Y I  V  D +
Sbjct: 256 ITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYNI--VDGDGI 313

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT----DQASPV 126
                           QD        G +  +  +D E    Y++ ++A     D     
Sbjct: 314 E-----LFEITTDYETQD--------GVVKLKKPVDFETKRAYSLKIEAANVHIDPKFIS 360

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
           +     T T+ ++ ++D D  P F   +Y   V E+ +     V+ ++ A D D  ANS 
Sbjct: 361 NGPFKDTVTVKIS-VEDADEPPMFLAPSYIHEVQENAAA--GTVVGRVHAKDPD-AANSP 416

Query: 187 IRYAIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
           IRY+ I  +T +   F+I+   G +   K LD E+     + + A +  +  +     + 
Sbjct: 417 IRYS-IDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNISVFAAEIHNRHQETKVPVA 475

Query: 245 INIRDVNDNAPRF---YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
           I + DVNDNAP+F   Y     ES          IV V A D D+  N          + 
Sbjct: 476 IRVLDVNDNAPKFAAPYEGFICESDHPKALSNQPIVTVSADDQDDTANGPRFIFSLPPEI 535

Query: 302 TGNVDLPI--TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
             N +  +    D  +G     G   R+ Q  Y L +  +DGG PP S+T T
Sbjct: 536 MHNPNFTVRDNRDNTAGVYARRGGFSRQKQDFYLLPIVISDGGIPPMSSTNT 587


>UniRef50_UPI0000F20039 Cluster: PREDICTED: hypothetical protein;
           n=4; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 997

 Score =  177 bits (431), Expect = 4e-42
 Identities = 184/645 (28%), Positives = 284/645 (44%), Gaps = 69/645 (10%)

Query: 10  QINVLDCNDHSPVF---------EMQQYEASVREGASSGTTV--LTLKATDQDIGKNAEV 58
           QI++ D ND+SP F         +   +E +V E +S+G  +  L +K  D D G+N+  
Sbjct: 34  QISIKDENDNSPEFYECEGEACMKKDNFEGNVDEHSSTGLAIANLNIKVKDLDGGENSRF 93

Query: 59  EYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVK 118
              ++    D                 VQ + +            ++D E      V + 
Sbjct: 94  NLHLDGPDKDAFR---VSPTSGMGESTVQVLVK---------DPQAVDYEIKQIMNVQII 141

Query: 119 ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178
           A D  +      +STAT+ +++ D NDN+P F ++ Y   V E     +  ++A I ATD
Sbjct: 142 AVDANAD----FTSTATVTIHLNDTNDNFPTFEKELYKEKVFEHCE--NGTIVATITATD 195

Query: 179 ADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVK--TLDYEQVRSYRLVIRAQDGGSPS 236
           AD      I Y ++  + +  F +   +G + +    TLD E  +SY L ++A D G+  
Sbjct: 196 ADAFDEGKITYKLMPESIRSLFGVHEKTGTIYVTNGDTLDREVTKSYTLTLQAFDSGN-- 253

Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYT 295
            + TT + I I D+NDNAP     +++  V EN      I      D D +  N  + Y 
Sbjct: 254 NTGTTVVEILILDINDNAPEMNRDIYEAFVQENEDFKIQIQATDRDDPDPDTQNNIVQYR 313

Query: 296 MTDK-DYTGNVDLPITIDPRSGWVYTSGQLDRET-----QAKYQLLVTATDGGDPPRSAT 349
           ++++  ++ N     +ID   GW+   G LDRE          QL+V A+D G P  S++
Sbjct: 314 ISEESSFSSN----FSIDLEHGWLTNKGDLDREAIDISQNGVIQLIVIASDLGTPSLSSS 369

Query: 350 ATXXXXXXXXXXXXXXFM-PGQYEVELAEDEPPGTPVVTLTATDADE---DNRLHYEITG 405
           A               ++ P  YE  + E    G  V  + A DAD+   +NR+ + IT 
Sbjct: 370 AKVNISVGDANDNAPRYLDPSPYEFRVKE-SVKGIYVGPVHAHDADQTDFNNRIFFSITD 428

Query: 406 GNTRGRFSITSQ----NGRGLITV--AQPLDFKQERR-YVLTVSATDSGGRSDTAMVQIN 458
           G+  G F I S+      RG ITV  +  LD++  R+ Y L V A+D G +SD A V I 
Sbjct: 429 GSF-GSFIIYSEAFSKGYRGNITVDPSVELDYESNRKEYTLKVQASDLGQKSDVAEVHII 487

Query: 459 ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE--ISNEA 516
           + D N+  P F +      V E+  +   V  +   D D   N  + Y L S     N  
Sbjct: 488 VEDVNDTPPEFPSG-MILKVDENTTLPVPVDTIKGKDVDT--NHSLIYELVSTKCQCNGT 544

Query: 517 VAHHDQQFVINPQTGAITTNK--LLDRETMSGYLLTVTARD--GGVPSLSDTTDVEISVV 572
           +    +++ I    G I  N   ++D E      LT    D    V S S    V I++V
Sbjct: 545 IGPCPEEWFIVESNGDIIANTEYVIDYEKCDVVFLTARVVDIYTEVGSNSSEGVVTINIV 604

Query: 573 DVNDNEP--VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615
           D+NDN P  VF Q  Y   ++E    GTSV++  ATD D   N +
Sbjct: 605 DINDNAPEFVFLQDFYVV-VIEKVDTGTSVARAYATDRDTADNNK 648



 Score =  167 bits (407), Expect = 3e-39
 Identities = 132/460 (28%), Positives = 206/460 (44%), Gaps = 27/460 (5%)

Query: 392 DADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA------QPLDFKQERRYVLTVSATD 445
           D  E++R +  + G + +  F ++  +G G  TV       Q +D++ ++   + + A D
Sbjct: 86  DGGENSRFNLHLDGPD-KDAFRVSPTSGMGESTVQVLVKDPQAVDYEIKQIMNVQIIAVD 144

Query: 446 SGGR-SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504
           +    + TA V I++ D N+  P FE   Y   VFE    GT V  ++ATD+D     +I
Sbjct: 145 ANADFTSTATVTIHLNDTNDNFPTFEKELYKEKVFEHCENGTIVATITATDADAFDEGKI 204

Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT 564
           TY L  E        H++   I      +T    LDRE    Y LT+ A D G  + + T
Sbjct: 205 TYKLMPESIRSLFGVHEKTGTIY-----VTNGDTLDREVTKSYTLTLQAFDSG--NNTGT 257

Query: 565 TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL-NGRIHYELDPK 623
           T VEI ++D+NDN P   + +Y A + E+      +      D D    N  + Y +  +
Sbjct: 258 TVVEILILDINDNAPEMNRDIYEAFVQENEDFKIQIQATDRDDPDPDTQNNIVQYRISEE 317

Query: 624 DREEGSFVIDPASGVIRTNKALDRESV-----ATHDLKAVAIDGGTPPQSSTVIVHIKIE 678
                +F ID   G +     LDRE++         L  +A D GTP  SS+  V+I + 
Sbjct: 318 SSFSSNFSIDLEHGWLTNKGDLDREAIDISQNGVIQLIVIASDLGTPSLSSSAKVNISVG 377

Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP-NAVVHYSIKGGDDSNSFSL 737
           D ND+ P +       +  + S  G  +G + AHD D+   N  + +SI  G   +    
Sbjct: 378 DANDNAPRYLDPSPYEFRVKESVKGIYVGPVHAHDADQTDFNNRIFFSITDGSFGSFIIY 437

Query: 738 ETRQGSDKAELVTM---VDLDYESPRKKYELVIRAASPPLWNDV-RVEILVTDVNDNAPV 793
                      +T+   V+LDYES RK+Y L ++A+     +DV  V I+V DVND  P 
Sbjct: 438 SEAFSKGYRGNITVDPSVELDYESNRKEYTLKVQASDLGQKSDVAEVHIIVEDVNDTPPE 497

Query: 794 MKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILS 833
                I+  +     PV P   +   D D    L Y ++S
Sbjct: 498 FPSGMILKVDENTTLPV-PVDTIKGKDVDTNHSLIYELVS 536



 Score =  145 bits (352), Expect = 1e-32
 Identities = 146/515 (28%), Positives = 224/515 (43%), Gaps = 54/515 (10%)

Query: 238 SNTTQLLINIRDVNDNAPRFYT---------SLFQESVSENVPIGYSI--VRVQAYDADE 286
           S   +L I+I+D NDN+P FY            F+ +V E+   G +I  + ++  D D 
Sbjct: 28  STIGELQISIKDENDNSPEFYECEGEACMKKDNFEGNVDEHSSTGLAIANLNIKVKDLDG 87

Query: 287 GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL--------DRETQAKYQLLVTA 338
           G N+     +   D          + P SG   ++ Q+        D E +    + + A
Sbjct: 88  GENSRFNLHLDGPDKDA-----FRVSPTSGMGESTVQVLVKDPQAVDYEIKQIMNVQIIA 142

Query: 339 TDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--ED 396
            D  +   ++TAT              F    Y+ ++ E    GT V T+TATDAD  ++
Sbjct: 143 VDA-NADFTSTATVTIHLNDTNDNFPTFEKELYKEKVFEHCENGTIVATITATDADAFDE 201

Query: 397 NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ 456
            ++ Y++   + R  F +  + G   +T    LD +  + Y LT+ A DSG  + T +V+
Sbjct: 202 GKITYKLMPESIRSLFGVHEKTGTIYVTNGDTLDREVTKSYTLTLQAFDSGNNTGTTVVE 261

Query: 457 INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI-NAQITYSLSSEISNE 515
           I I D N+ AP      Y A V E+      +      D D    N  + Y +S E S  
Sbjct: 262 ILILDINDNAPEMNRDIYEAFVQENEDFKIQIQATDRDDPDPDTQNNIVQYRISEESS-- 319

Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRE----TMSGYL-LTVTARDGGVPSLSDTTDVEIS 570
                   F I+ + G +T    LDRE    + +G + L V A D G PSLS +  V IS
Sbjct: 320 ----FSSNFSIDLEHGWLTNKGDLDREAIDISQNGVIQLIVIASDLGTPSLSSSAKVNIS 375

Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGS 629
           V D NDN P +         +++++ G  V  V A DAD    N RI + +   D   GS
Sbjct: 376 VGDANDNAPRYLDPSPYEFRVKESVKGIYVGPVHAHDADQTDFNNRIFFSI--TDGSFGS 433

Query: 630 FVI--DPASGVIRTNKALD-------RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680
           F+I  +  S   R N  +D         +   + LK  A D G   +S    VHI +ED+
Sbjct: 434 FIIYSEAFSKGYRGNITVDPSVELDYESNRKEYTLKVQASDLG--QKSDVAEVHIIVEDV 491

Query: 681 NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
           ND+PP F S  +   + EN+ +   +  I+  D D
Sbjct: 492 NDTPPEFPSG-MILKVDENTTLPVPVDTIKGKDVD 525



 Score =  128 bits (308), Expect = 3e-27
 Identities = 171/619 (27%), Positives = 270/619 (43%), Gaps = 104/619 (16%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I++ D ND+ P FE + Y+  V E   +GT V T+ ATD D     ++ Y         L
Sbjct: 157 IHLNDTNDNFPTFEKELYKEKVFEHCENGTIVATITATDADAFDEGKITYK--------L 208

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRA-SLDREKVARYTVLVKATDQASPVSD 128
            PE            ++ +F +  ++G + +T   +LDRE    YT+ ++A D     S 
Sbjct: 209 MPES-----------IRSLFGVHEKTGTIYVTNGDTLDREVTKSYTLTLQAFD-----SG 252

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD----VGAN 184
             + T  + + I+D NDN P+ +   Y   V E+    D  +  +I+ATD D       N
Sbjct: 253 NNTGTTVVEILILDINDNAPEMNRDIYEAFVQEN---EDFKI--QIQATDRDDPDPDTQN 307

Query: 185 SAIRYAIIGGNT-QMQFSID------SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237
           + ++Y I   ++    FSID      +  GD+   + +D  Q    +L++ A D G+PS 
Sbjct: 308 NIVQYRISEESSFSSNFSIDLEHGWLTNKGDLDR-EAIDISQNGVIQLIVIASDLGTPSL 366

Query: 238 SNTTQLLINIRDVNDNAPRFY-TSLFQESVSENVPIGYSIVRVQAYDADE-GVNAELTYT 295
           S++ ++ I++ D NDNAPR+   S ++  V E+V  G  +  V A+DAD+   N  + ++
Sbjct: 367 SSSAKVNISVGDANDNAPRYLDPSPYEFRVKESVK-GIYVGPVHAHDADQTDFNNRIFFS 425

Query: 296 MTD--------------KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK-YQLLVTATD 340
           +TD              K Y GN    IT+DP       S +LD E+  K Y L V A+D
Sbjct: 426 ITDGSFGSFIIYSEAFSKGYRGN----ITVDP-------SVELDYESNRKEYTLKVQASD 474

Query: 341 GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH 400
            G   +S  A               F  G   +++ E+     PV T+   D D ++ L 
Sbjct: 475 LGQ--KSDVAEVHIIVEDVNDTPPEFPSGMI-LKVDENTTLPVPVDTIKGKDVDTNHSLI 531

Query: 401 YEI---------TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA----TDSG 447
           YE+         T G     + I   NG  +      +D+++     LT       T+ G
Sbjct: 532 YELVSTKCQCNGTIGPCPEEWFIVESNGDIIANTEYVIDYEKCDVVFLTARVVDIYTEVG 591

Query: 448 GRSDTAMVQINITDANNYAPVFE-NAPYTASVFEDAPIGTTVLVVSATDSDVGIN----- 501
             S   +V INI D N+ AP F     +   V E    GT+V    ATD D   N     
Sbjct: 592 SNSSEGVVTINIVDINDNAPEFVFLQDFYVVVIEKVDTGTSVARAYATDRDTADNNKKTK 651

Query: 502 ---AQITYSLSSEISNEAV----AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554
               +IT+  S   + E++     + DQ+      T  I + K +D      +++ V A 
Sbjct: 652 FQVNKITFIGSEGNTTESLFLYADNFDQEDAEGRYTAYIRSQKAMDNNKRGKFMVEVEAV 711

Query: 555 DGGVPSLSDTTDVEISVVD 573
           +G    LS T  VE+  VD
Sbjct: 712 NG---KLSTTGVVELLTVD 727



 Score =  124 bits (298), Expect = 5e-26
 Identities = 185/700 (26%), Positives = 287/700 (41%), Gaps = 71/700 (10%)

Query: 119 ATDQASPVSDRLSST-ATIHVNIIDDNDNYPQFSE---------KTYTVSVDEDISVTDN 168
           A++    V++ ++ST   + ++I D+NDN P+F E           +  +VDE  S    
Sbjct: 15  ASETMPNVNEVIASTIGELQISIKDENDNSPEFYECEGEACMKKDNFEGNVDEHSSTGLA 74

Query: 169 PVIAKIKATDADVGANSAIRYAIIGGNTQ-MQFSIDSLSGDVS---LVK---TLDYEQVR 221
                IK  D D G NS     + G +    + S  S  G+ +   LVK    +DYE  +
Sbjct: 75  IANLNIKVKDLDGGENSRFNLHLDGPDKDAFRVSPTSGMGESTVQVLVKDPQAVDYEIKQ 134

Query: 222 SYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA 281
              + I A D  +   S  T + I++ D NDN P F   L++E V E+   G  +  + A
Sbjct: 135 IMNVQIIAVDANADFTSTAT-VTIHLNDTNDNFPTFEKELYKEKVFEHCENGTIVATITA 193

Query: 282 YDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY-TSGQ-LDRETQAKYQLLVTAT 339
            DAD     ++TY +  +    ++     +  ++G +Y T+G  LDRE    Y L + A 
Sbjct: 194 TDADAFDEGKITYKLMPE----SIRSLFGVHEKTGTIYVTNGDTLDREVTKSYTLTLQAF 249

Query: 340 DGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--- 396
           D G+   + T                     YE  + E+E     +      D D D   
Sbjct: 250 DSGN--NTGTTVVEILILDINDNAPEMNRDIYEAFVQENEDFKIQIQATDRDDPDPDTQN 307

Query: 397 NRLHYEITGGNT-RGRFSITSQNG----RGLITVAQPLDFKQERRYVLTVSATDSG--GR 449
           N + Y I+  ++    FSI  ++G    +G +   + +D  Q     L V A+D G    
Sbjct: 308 NIVQYRISEESSFSSNFSIDLEHGWLTNKGDLD-REAIDISQNGVIQLIVIASDLGTPSL 366

Query: 450 SDTAMVQINITDANNYAPVF-ENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYS 507
           S +A V I++ DAN+ AP + + +PY   V E    G  V  V A D+D    N +I +S
Sbjct: 367 SSSAKVNISVGDANDNAPRYLDPSPYEFRVKESVK-GIYVGPVHAHDADQTDFNNRIFFS 425

Query: 508 LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG---YLLTVTARDGGVPSLSDT 564
           ++       + +   +       G IT +  ++ +  S    Y L V A D G    SD 
Sbjct: 426 ITDGSFGSFIIY--SEAFSKGYRGNITVDPSVELDYESNRKEYTLKVQASDLG--QKSDV 481

Query: 565 TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPK 623
            +V I V DVND  P F   +    + E+  +   V  +   D D   N  + YEL   K
Sbjct: 482 AEVHIIVEDVNDTPPEFPSGM-ILKVDENTTLPVPVDTIKGKDVDT--NHSLIYELVSTK 538

Query: 624 DREEGS--------FVIDPASGVI-RTNKALDRESVATHDLKAVAIDGGTP--PQSSTVI 672
            +  G+        F+++    +I  T   +D E      L A  +D  T     SS  +
Sbjct: 539 CQCNGTIGPCPEEWFIVESNGDIIANTEYVIDYEKCDVVFLTARVVDIYTEVGSNSSEGV 598

Query: 673 VHIKIEDINDSPP--VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD 730
           V I I DIND+ P  VF  D     I E    GT++    A D D   N     + K   
Sbjct: 599 VTINIVDINDNAPEFVFLQDFYVVVI-EKVDTGTSVARAYATDRDTADN-----NKKTKF 652

Query: 731 DSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVIRA 769
             N  +    +G+    L    D  D E    +Y   IR+
Sbjct: 653 QVNKITFIGSEGNTTESLFLYADNFDQEDAEGRYTAYIRS 692



 Score = 41.5 bits (93), Expect = 0.32
 Identities = 34/137 (24%), Positives = 65/137 (47%), Gaps = 11/137 (8%)

Query: 11  INVLDCNDHSPVFE-MQQYEASVREGASSGTTVLTLKATDQDIG-KNAEVEYTIELVTAD 68
           IN++D ND++P F  +Q +   V E   +GT+V    ATD+D    N + ++ +  +T  
Sbjct: 601 INIVDINDNAPEFVFLQDFYVVVIEKVDTGTSVARAYATDRDTADNNKKTKFQVNKIT-- 658

Query: 69  TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALL-TRASLDREKVARYTVLVKATDQASPVS 127
            +  E              D    +GR  A + ++ ++D  K  ++ V V+A      V+
Sbjct: 659 FIGSEGNTTESLFLYADNFDQEDAEGRYTAYIRSQKAMDNNKRGKFMVEVEA------VN 712

Query: 128 DRLSSTATIHVNIIDDN 144
            +LS+T  + +  +D +
Sbjct: 713 GKLSTTGVVELLTVDSS 729


>UniRef50_UPI0000E20B3B Cluster: PREDICTED: similar to Protocadherin
           gamma A2 precursor (PCDH-gamma-A2) isoform 4; n=3;
           Catarrhini|Rep: PREDICTED: similar to Protocadherin
           gamma A2 precursor (PCDH-gamma-A2) isoform 4 - Pan
           troglodytes
          Length = 878

 Score =  172 bits (418), Expect = 1e-40
 Identities = 113/362 (31%), Positives = 180/362 (49%), Gaps = 14/362 (3%)

Query: 370 QYEVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQ---NGRGLITV 425
           + E++++E   PG  +    A DAD  +N L       N      + S    N    + +
Sbjct: 137 ELELKISETTTPGFRIPLKNAHDADVGENALQKYALNPNDHFSLDVRSGADGNKYPELVL 196

Query: 426 AQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
            + LD ++E  + L + A+D G    S T+ + + + DAN+ APVF    Y  S+ E+ P
Sbjct: 197 ERALDREEEAVHHLVLVASDGGDPVLSGTSRICVKVLDANDNAPVFTQPEYRISIPENTP 256

Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
           +GT +L V+ATD+D G  AQ+ Y L      ++     + F +   +G +T  K LD E 
Sbjct: 257 VGTRILTVTATDADEGYYAQVVYFLE-----KSPGETSEVFELKSTSGELTIIKDLDYED 311

Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
            + + + + A+DG  P L     V ++V+DVNDN P F     T+++ ED+L GT +   
Sbjct: 312 ATFHEIDIEAQDG--PGLLTRAKVIVTVLDVNDNAPEFYMTSATSSVSEDSLPGTIIGLF 369

Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
              D D G N      L      +    +D    ++ T +ALDRE  + +++   A DGG
Sbjct: 370 NVHDRDSGQNAFTTCSLPENLPFKLEKSVDNYYRLV-TTRALDREQFSFYNITLTAKDGG 428

Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
            P  S+   + +++ DIND+ P F     + YI EN+P G ++  + AHDPD   NA V 
Sbjct: 429 NPSLSTDAHILLQVADINDNAPAFSRTSYSTYIPENNPRGASVFSVTAHDPDSNDNAHVT 488

Query: 724 YS 725
           YS
Sbjct: 489 YS 490



 Score =  167 bits (407), Expect = 3e-39
 Identities = 124/403 (30%), Positives = 192/403 (47%), Gaps = 48/403 (11%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ + D ND++P F +++ E  + E  + G  +    A D D+G+NA  +Y         
Sbjct: 120 EVEITDINDNAPRFGVEELELKISETTTPGFRIPLKNAHDADVGENALQKY--------A 171

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGA-------LLTRASLDREKVARYTVLVKATDQ 122
           LNP D               F +D RSGA       L+   +LDRE+ A + +++ A+D 
Sbjct: 172 LNPNDH--------------FSLDVRSGADGNKYPELVLERALDREEEAVHHLVLVASDG 217

Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
             PV   LS T+ I V ++D NDN P F++  Y +S+ E+  V     I  + ATDAD G
Sbjct: 218 GDPV---LSGTSRICVKVLDANDNAPVFTQPEYRISIPENTPVGTR--ILTVTATDADEG 272

Query: 183 ANSAIRYAI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240
             + + Y +    G T   F + S SG+++++K LDYE    + + I AQDG  P     
Sbjct: 273 YYAQVVYFLEKSPGETSEVFELKSTSGELTIIKDLDYEDATFHEIDIEAQDG--PGLLTR 330

Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300
            ++++ + DVNDNAP FY +    SVSE+   G  I     +D D G NA  T ++ +  
Sbjct: 331 AKVIVTVLDVNDNAPEFYMTSATSSVSEDSLPGTIIGLFNVHDRDSGQNAFTTCSLPE-- 388

Query: 301 YTGNVDLPITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357
                +LP  ++      Y   T+  LDRE  + Y + +TA DGG+P  S  A       
Sbjct: 389 -----NLPFKLEKSVDNYYRLVTTRALDREQFSFYNITLTAKDGGNPSLSTDAHILLQVA 443

Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH 400
                   F    Y   + E+ P G  V ++TA D D ++  H
Sbjct: 444 DINDNAPAFSRTSYSTYIPENNPRGASVFSVTAHDPDSNDNAH 486



 Score =  159 bits (386), Expect = 1e-36
 Identities = 139/484 (28%), Positives = 216/484 (44%), Gaps = 27/484 (5%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           +F ++ RSG+L+T   +DRE++   +           + D+L+   ++ V I D NDN P
Sbjct: 74  LFALNPRSGSLVTANRIDREELCAQSAPCLLNFNIL-LEDKLT-IYSVEVEITDINDNAP 131

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG- 207
           +F  +   + + E  + T    I    A DADVG N+  +YA+   N    FS+D  SG 
Sbjct: 132 RFGVEELELKISE--TTTPGFRIPLKNAHDADVGENALQKYAL---NPNDHFSLDVRSGA 186

Query: 208 ------DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261
                 ++ L + LD E+   + LV+ A DGG P  S T+++ + + D NDNAP F    
Sbjct: 187 DGNKYPELVLERALDREEEAVHHLVLVASDGGDPVLSGTSRICVKVLDANDNAPVFTQPE 246

Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321
           ++ S+ EN P+G  I+ V A DADEG  A++ Y +  +   G       +   SG +   
Sbjct: 247 YRISIPENTPVGTRILTVTATDADEGYYAQVVYFL--EKSPGETSEVFELKSTSGELTII 304

Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381
             LD E    +++ + A DG  P     A               F        ++ED  P
Sbjct: 305 KDLDYEDATFHEIDIEAQDG--PGLLTRAKVIVTVLDVNDNAPEFYMTSATSSVSEDSLP 362

Query: 382 GTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440
           GT +      D D   N         N   +   +  N   L+T  + LD +Q   Y +T
Sbjct: 363 GTIIGLFNVHDRDSGQNAFTTCSLPENLPFKLEKSVDNYYRLVT-TRALDREQFSFYNIT 421

Query: 441 VSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498
           ++A D G    S  A + + + D N+ AP F    Y+  + E+ P G +V  V+A D D 
Sbjct: 422 LTAKDGGNPSLSTDAHILLQVADINDNAPAFSRTSYSTYIPENNPRGASVFSVTAHDPDS 481

Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINP--QTGAITTNKLLDRETMSGYLLT-VTA-- 553
             NA +TYS   +       + +   ++ P   T   T  +L  R    GYL+T V A  
Sbjct: 482 NDNAHVTYSFVEDTVLVLDQNDNPPEILYPAFPTDGSTGVELAPRSAEPGYLVTKVVAVD 541

Query: 554 RDGG 557
           RD G
Sbjct: 542 RDSG 545



 Score =  150 bits (364), Expect = 5e-34
 Identities = 112/342 (32%), Positives = 163/342 (47%), Gaps = 14/342 (4%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
           V++ ITD N+ AP F        + E    G  + + +A D+DVG NA   Y+L+    N
Sbjct: 119 VEVEITDINDNAPRFGVEELELKISETTTPGFRIPLKNAHDADVGENALQKYALNP---N 175

Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
           +  +   +      +   +   + LDRE  + + L + A DGG P LS T+ + + V+D 
Sbjct: 176 DHFSLDVRSGADGNKYPELVLERALDREEEAVHHLVLVASDGGDPVLSGTSRICVKVLDA 235

Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS-FVID 633
           NDN PVF Q  Y  +I E+  VGT +  V ATDAD G   ++ Y L+    E    F + 
Sbjct: 236 NDNAPVFTQPEYRISIPENTPVGTRILTVTATDADEGYYAQVVYFLEKSPGETSEVFELK 295

Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693
             SG +   K LD E    H++   A DG  P   +   V + + D+ND+ P F     T
Sbjct: 296 STSGELTIIKDLDYEDATFHEIDIEAQDG--PGLLTRAKVIVTVLDVNDNAPEFYMTSAT 353

Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753
             +SE+S  GT IG    HD D G NA    S+    ++  F LE +   +   LVT   
Sbjct: 354 SSVSEDSLPGTIIGLFNVHDRDSGQNAFTTCSL---PENLPFKLE-KSVDNYYRLVTTRA 409

Query: 754 LDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792
           LD E     Y + + A    +P L  D  + + V D+NDNAP
Sbjct: 410 LDREQ-FSFYNITLTAKDGGNPSLSTDAHILLQVADINDNAP 450



 Score =  136 bits (329), Expect = 8e-30
 Identities = 105/312 (33%), Positives = 142/312 (45%), Gaps = 20/312 (6%)

Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTT-DVEISVVDVNDNEPV 580
           Q F +NP++G++ T   +DRE +             +     T   VE+ + D+NDN P 
Sbjct: 73  QLFALNPRSGSLVTANRIDREELCAQSAPCLLNFNILLEDKLTIYSVEVEITDINDNAPR 132

Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV-- 638
           F  +     I E    G  +    A DADVG N    Y L+P D     F +D  SG   
Sbjct: 133 FGVEELELKISETTTPGFRIPLKNAHDADVGENALQKYALNPNDH----FSLDVRSGADG 188

Query: 639 -----IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693
                +   +ALDRE  A H L  VA DGG P  S T  + +K+ D ND+ PVF      
Sbjct: 189 NKYPELVLERALDREEEAVHHLVLVASDGGDPVLSGTSRICVKVLDANDNAPVFTQPEYR 248

Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK--GGDDSNSFSLETRQGSDKAELVTM 751
             I EN+P+GT I  + A D DEG  A V Y ++   G+ S  F L++  G    EL  +
Sbjct: 249 ISIPENTPVGTRILTVTATDADEGYYAQVVYFLEKSPGETSEVFELKSTSG----ELTII 304

Query: 752 VDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV 810
            DLDYE     +E+ I A   P L    +V + V DVNDNAP         +  +D  P 
Sbjct: 305 KDLDYED-ATFHEIDIEAQDGPGLLTRAKVIVTVLDVNDNAPEFYMTSATSSVSEDSLPG 363

Query: 811 GPFGRVPAYDAD 822
              G    +D D
Sbjct: 364 TIIGLFNVHDRD 375



 Score =  134 bits (325), Expect = 3e-29
 Identities = 90/289 (31%), Positives = 139/289 (48%), Gaps = 26/289 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           + VLD ND++PVF   +Y  S+ E    GT +LT+ ATD D G  A+V Y +E    +T 
Sbjct: 230 VKVLDANDNAPVFTQPEYRISIPENTPVGTRILTVTATDADEGYYAQVVYFLEKSPGET- 288

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                            +VF +   SG L     LD E    + + ++A D        L
Sbjct: 289 ----------------SEVFELKSTSGELTIIKDLDYEDATFHEIDIEAQDGPG-----L 327

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            + A + V ++D NDN P+F   + T SV ED       +I      D D G N+    +
Sbjct: 328 LTRAKVIVTVLDVNDNAPEFYMTSATSSVSEDS--LPGTIIGLFNVHDRDSGQNAFTTCS 385

Query: 191 IIGGNT-QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
           +      +++ S+D+    V+  + LD EQ   Y + + A+DGG+PS S    +L+ + D
Sbjct: 386 LPENLPFKLEKSVDNYYRLVT-TRALDREQFSFYNITLTAKDGGNPSLSTDAHILLQVAD 444

Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
           +NDNAP F  + +   + EN P G S+  V A+D D   NA +TY+  +
Sbjct: 445 INDNAPAFSRTSYSTYIPENNPRGASVFSVTAHDPDSNDNAHVTYSFVE 493



 Score = 46.4 bits (105), Expect = 0.011
 Identities = 28/117 (23%), Positives = 49/117 (41%), Gaps = 5/117 (4%)

Query: 138 VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP-----VIAKIKATDADVGANSAIRYAII 192
           V ++D NDN P+     +       + +         ++ K+ A D D G N+ + Y ++
Sbjct: 496 VLVLDQNDNPPEILYPAFPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYHLL 555

Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
             +    FS+   +G+V   + L         LV+  QD G P  S T  L + + D
Sbjct: 556 KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVAD 612



 Score = 45.2 bits (102), Expect = 0.026
 Identities = 39/136 (28%), Positives = 54/136 (39%), Gaps = 15/136 (11%)

Query: 227 IRAQDGGSPSRSNTTQLLIN----IRDVNDNAPRFYTSLFQESVSENVPI-------GYS 275
           + A D  S   ++ T   +     + D NDN P      F    S  V +       GY 
Sbjct: 474 VTAHDPDSNDNAHVTYSFVEDTVLVLDQNDNPPEILYPAFPTDGSTGVELAPRSAEPGYL 533

Query: 276 IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL 335
           + +V A D D G NA L+Y +      G   + +     +G V T+  L      K  L+
Sbjct: 534 VTKVVAVDRDSGQNAWLSYHLLKASEPGLFSVGL----HTGEVRTARALLDRDALKQSLV 589

Query: 336 VTATDGGDPPRSATAT 351
           V   D G PP SAT T
Sbjct: 590 VAVQDHGQPPLSATVT 605



 Score = 45.2 bits (102), Expect = 0.026
 Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 10/119 (8%)

Query: 569 ISVVDVNDNEPVFKQQLYTAN-------IMEDALVGTSVSQVGATDADVGLNGRIHYELD 621
           + V+D NDN P      +  +           A  G  V++V A D D G N  + Y L 
Sbjct: 496 VLVLDQNDNPPEILYPAFPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYHL- 554

Query: 622 PKDREEGSFVIDPASGVIRTNKAL-DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679
            K  E G F +   +G +RT +AL DR+++    + AV  D G PP S+TV + + + D
Sbjct: 555 LKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQ-DHGQPPLSATVTLTVAVAD 612



 Score = 40.7 bits (91), Expect = 0.57
 Identities = 21/67 (31%), Positives = 30/67 (44%)

Query: 8   HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
           H  + V D ND++P F    Y   + E    G +V ++ A D D   NA V Y+    T 
Sbjct: 437 HILLQVADINDNAPAFSRTSYSTYIPENNPRGASVFSVTAHDPDSNDNAHVTYSFVEDTV 496

Query: 68  DTLNPED 74
             L+  D
Sbjct: 497 LVLDQND 503



 Score = 37.1 bits (82), Expect = 7.0
 Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 9/90 (10%)

Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK-LLDRET 543
           G  V  V A D D G NA ++Y L         A     F +   TG + T + LLDR+ 
Sbjct: 531 GYLVTKVVAVDRDSGQNAWLSYHLLK-------ASEPGLFSVGLHTGEVRTARALLDRDA 583

Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
           +   L+ V  +D G P LS T  + ++V D
Sbjct: 584 LKQSLV-VAVQDHGQPPLSATVTLTVAVAD 612


>UniRef50_Q6V1P8 Cluster: Protocadherin protein; n=6;
           Catarrhini|Rep: Protocadherin protein - Homo sapiens
           (Human)
          Length = 702

 Score =  172 bits (418), Expect = 1e-40
 Identities = 141/433 (32%), Positives = 203/433 (46%), Gaps = 43/433 (9%)

Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
           D+ L++ LD E+  ++RL I A DGG P R+    + + + D NDN P F    ++ +V 
Sbjct: 240 DLVLLRRLDREEAAAHRLQIEAWDGGRPRRTGLLSVELRVLDENDNPPVFEQDEYRAAVR 299

Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD--------LPITIDPRSGWVY 319
           E+   G  + RV+A D D G N  + Y++  +   G               ++  SG V 
Sbjct: 300 EDAQPGAEVCRVRATDRDLGPNGFVRYSVRARQVPGAGSGGGALGDAAYFAVEELSGVVR 359

Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX----XXXXXFMPGQYEVEL 375
               LDRE QA +QL+V A DGG  P  AT                    F+       +
Sbjct: 360 VWRPLDREAQAWHQLVVEARDGGAEPEVATVRVSIAVLDVNDNRPAIHVLFLTEGGVARV 419

Query: 376 AEDEPPGTPVVTLTATDADEDNRLHYEITG----GNTRGRFSITSQNGRG---------- 421
           +E   PG  V  ++ +DAD D     E TG    G   G  S++ + G G          
Sbjct: 420 SEGARPGDYVARVSVSDADGDWEKEDEATGELGVGLGDGSISLSLEGGEGDFALLPGGPP 479

Query: 422 ---LITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTA 476
               + V  PLD +    Y L + ATD+G    S    + + + D N+  P+F    Y A
Sbjct: 480 GVFFLCVEGPLDRESRDLYELLLVATDAGSPPLSTEETLLLRVADLNDQPPLFSQQHYKA 539

Query: 477 SVFEDAPIGTTVLVVSATDSDVG--INAQITYS---LSS-----EISNEAV--AHHDQQF 524
           SV E A  GT V+ VSA+D+D     +A + Y+   LS+      + ++ V  A     F
Sbjct: 540 SVSEAAAPGTVVMWVSASDADEAGSDHAWLRYTVVQLSAPCNLGSLQSKMVHTAECGPSF 599

Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584
            I+ ++GAI+T + LDRE      L V A+D G P LS T  V I+V DVNDNEP+F +Q
Sbjct: 600 AIDSESGAISTIRTLDREVQEAVELKVVAQDLGEPPLSATCLVSITVDDVNDNEPIFWRQ 659

Query: 585 LYTANIMEDALVG 597
           +Y A I E A VG
Sbjct: 660 VYNATIAEHAPVG 672



 Score =  161 bits (392), Expect = 2e-37
 Identities = 149/543 (27%), Positives = 233/543 (42%), Gaps = 61/543 (11%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           +  +I V D NDHSP F +   +  V E +  GT      A D D G  +   YT+   +
Sbjct: 144 VQVEIRVNDVNDHSPRFPLDSLQLDVSELSPPGTAFRLPVAHDPDAGLFSTQGYTLVQPS 203

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-----LTRASLDREKVARYTVLVKATD 121
               +P                   + G S  L     +    LDRE+ A + + ++A D
Sbjct: 204 DLPKDPAGPFFQLRYRTPGPLPSPLLPGSSSPLEPLDLVLLRRLDREEAAAHRLQIEAWD 263

Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181
              P   R +   ++ + ++D+NDN P F +  Y  +V ED        + +++ATD D+
Sbjct: 264 GGRP---RRTGLLSVELRVLDENDNPPVFEQDEYRAAVREDAQ--PGAEVCRVRATDRDL 318

Query: 182 GANSAIRYAI---------IGGNT---QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA 229
           G N  +RY++          GG        F+++ LSG V + + LD E    ++LV+ A
Sbjct: 319 GPNGFVRYSVRARQVPGAGSGGGALGDAAYFAVEELSGVVRVWRPLDREAQAWHQLVVEA 378

Query: 230 QDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES----VSENVPIGYSIVRVQAYDAD 285
           +DGG+     T ++ I + DVNDN P  +     E     VSE    G  + RV   DAD
Sbjct: 379 RDGGAEPEVATVRVSIAVLDVNDNRPAIHVLFLTEGGVARVSEGARPGDYVARVSVSDAD 438

Query: 286 ------EGVNAELTYTMTDKDYT-----GNVDLPITIDPRSG--WVYTSGQLDRETQAKY 332
                 +    EL   + D   +     G  D  +      G  ++   G LDRE++  Y
Sbjct: 439 GDWEKEDEATGELGVGLGDGSISLSLEGGEGDFALLPGGPPGVFFLCVEGPLDRESRDLY 498

Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392
           +LL+ ATD G PP S   T              F    Y+  ++E   PGT V+ ++A+D
Sbjct: 499 ELLLVATDAGSPPLSTEETLLLRVADLNDQPPLFSQQHYKASVSEAAAPGTVVMWVSASD 558

Query: 393 ADEDNR----LHYEITG-------GNTRGRFSITSQNG--------RGLITVAQPLDFKQ 433
           ADE       L Y +         G+ + +   T++ G         G I+  + LD + 
Sbjct: 559 ADEAGSDHAWLRYTVVQLSAPCNLGSLQSKMVHTAECGPSFAIDSESGAISTIRTLDREV 618

Query: 434 ERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL-V 490
           +    L V A D G    S T +V I + D N+  P+F    Y A++ E AP+G   L +
Sbjct: 619 QEAVELKVVAQDLGEPPLSATCLVSITVDDVNDNEPIFWRQVYNATIAEHAPVGHCFLQL 678

Query: 491 VSA 493
           +SA
Sbjct: 679 ISA 681



 Score =  156 bits (379), Expect = 7e-36
 Identities = 162/570 (28%), Positives = 242/570 (42%), Gaps = 72/570 (12%)

Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259
           F +   +G +   + LD E+   Y  V     G         Q+ I + DVND++PRF  
Sbjct: 109 FHVHPDTGIIRTARRLDRERRDHYSFVAATLLGA------VVQVEIRVNDVNDHSPRFPL 162

Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD-----KDYTGNV--------- 305
              Q  VSE  P G +     A+D D G+ +   YT+       KD  G           
Sbjct: 163 DSLQLDVSELSPPGTAFRLPVAHDPDAGLFSTQGYTLVQPSDLPKDPAGPFFQLRYRTPG 222

Query: 306 DLPITIDPRSGW------VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
            LP  + P S        +    +LDRE  A ++L + A DGG P R+   +        
Sbjct: 223 PLPSPLLPGSSSPLEPLDLVLLRRLDREEAAAHRLQIEAWDGGRPRRTGLLSVELRVLDE 282

Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEI---------TGGNT 408
                 F   +Y   + ED  PG  V  + ATD D   +  + Y +         +GG  
Sbjct: 283 NDNPPVFEQDEYRAAVREDAQPGAEVCRVRATDRDLGPNGFVRYSVRARQVPGAGSGGGA 342

Query: 409 RGRFSITS-QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNY 465
            G  +  + +   G++ V +PLD + +  + L V A D G   + A V+++I   D N+ 
Sbjct: 343 LGDAAYFAVEELSGVVRVWRPLDREAQAWHQLVVEARDGGAEPEVATVRVSIAVLDVNDN 402

Query: 466 AP----VFENAPYTASVFEDAPIGTTVLVVSATDSDVG------INAQITYSLSSEISNE 515
            P    +F      A V E A  G  V  VS +D+D           ++   L     + 
Sbjct: 403 RPAIHVLFLTEGGVARVSEGARPGDYVARVSVSDADGDWEKEDEATGELGVGLGDGSISL 462

Query: 516 AVAHHDQQFVINP--QTGA--ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571
           ++   +  F + P    G   +     LDRE+   Y L + A D G P LS    + + V
Sbjct: 463 SLEGGEGDFALLPGGPPGVFFLCVEGPLDRESRDLYELLLVATDAGSPPLSTEETLLLRV 522

Query: 572 VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD-------------VGLN----- 613
            D+ND  P+F QQ Y A++ E A  GT V  V A+DAD             V L+     
Sbjct: 523 ADLNDQPPLFSQQHYKASVSEAAAPGTVVMWVSASDADEAGSDHAWLRYTVVQLSAPCNL 582

Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673
           G +  ++        SF ID  SG I T + LDRE     +LK VA D G PP S+T +V
Sbjct: 583 GSLQSKMVHTAECGPSFAIDSESGAISTIRTLDREVQEAVELKVVAQDLGEPPLSATCLV 642

Query: 674 HIKIEDINDSPPVFESDCLTFYISENSPIG 703
            I ++D+ND+ P+F        I+E++P+G
Sbjct: 643 SITVDDVNDNEPIFWRQVYNATIAEHAPVG 672



 Score =  139 bits (336), Expect = 1e-30
 Identities = 129/419 (30%), Positives = 191/419 (45%), Gaps = 52/419 (12%)

Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFE 480
           + + + LD ++   + L + A D G    T +  V++ + D N+  PVFE   Y A+V E
Sbjct: 241 LVLLRRLDREEAAAHRLQIEAWDGGRPRRTGLLSVELRVLDENDNPPVFEQDEYRAAVRE 300

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEI-----SNEAVAHHDQQFVINPQTGAITT 535
           DA  G  V  V ATD D+G N  + YS+ +       S          F +   +G +  
Sbjct: 301 DAQPGAEVCRVRATDRDLGPNGFVRYSVRARQVPGAGSGGGALGDAAYFAVEELSGVVRV 360

Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT----ANIM 591
            + LDRE  + + L V ARDGG      T  V I+V+DVNDN P       T    A + 
Sbjct: 361 WRPLDREAQAWHQLVVEARDGGAEPEVATVRVSIAVLDVNDNRPAIHVLFLTEGGVARVS 420

Query: 592 EDALVGTSVSQVGATDAD--------------VGL-NGRIHYELDPKDREEGSFVIDPAS 636
           E A  G  V++V  +DAD              VGL +G I   L+     EG F + P  
Sbjct: 421 EGARPGDYVARVSVSDADGDWEKEDEATGELGVGLGDGSISLSLEGG---EGDFALLPGG 477

Query: 637 --GV--IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692
             GV  +     LDRES   ++L  VA D G+PP S+   + +++ D+ND PP+F     
Sbjct: 478 PPGVFFLCVEGPLDRESRDLYELLLVATDAGSPPLSTEETLLLRVADLNDQPPLFSQQHY 537

Query: 693 TFYISENSPIGTTIGEIRAHDPDE--GPNAVVHYS-IKGGDDSNSFSLETRQ-------- 741
              +SE +  GT +  + A D DE    +A + Y+ ++     N  SL+++         
Sbjct: 538 KASVSEAAAPGTVVMWVSASDADEAGSDHAWLRYTVVQLSAPCNLGSLQSKMVHTAECGP 597

Query: 742 ----GSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPV 793
                S+   + T+  LD E  ++  EL + A     PPL     V I V DVNDN P+
Sbjct: 598 SFAIDSESGAISTIRTLDRE-VQEAVELKVVAQDLGEPPLSATCLVSITVDDVNDNEPI 655



 Score =   99 bits (238), Expect = 9e-19
 Identities = 99/307 (32%), Positives = 135/307 (43%), Gaps = 45/307 (14%)

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583
           F ++P TG I T + LDRE    Y        G V        VEI V DVND+ P F  
Sbjct: 109 FHVHPDTGIIRTARRLDRERRDHYSFVAATLLGAV------VQVEIRVNDVNDHSPRFPL 162

Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD-----PKD----------REEG 628
                ++ E +  GT+     A D D GL     Y L      PKD          R  G
Sbjct: 163 DSLQLDVSELSPPGTAFRLPVAHDPDAGLFSTQGYTLVQPSDLPKDPAGPFFQLRYRTPG 222

Query: 629 ----------SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678
                     S  ++P   V+   + LDRE  A H L+  A DGG P ++  + V +++ 
Sbjct: 223 PLPSPLLPGSSSPLEPLDLVLL--RRLDREEAAAHRLQIEAWDGGRPRRTGLLSVELRVL 280

Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG----GDDSNS 734
           D ND+PPVFE D     + E++  G  +  +RA D D GPN  V YS++     G  S  
Sbjct: 281 DENDNPPVFEQDEYRAAVREDAQPGAEVCRVRATDRDLGPNGFVRYSVRARQVPGAGSGG 340

Query: 735 FSLETRQGSDKAELVTMV----DLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDV 787
            +L         EL  +V     LD E+ +  ++LV+ A    + P    VRV I V DV
Sbjct: 341 GALGDAAYFAVEELSGVVRVWRPLDREA-QAWHQLVVEARDGGAEPEVATVRVSIAVLDV 399

Query: 788 NDNAPVM 794
           NDN P +
Sbjct: 400 NDNRPAI 406


>UniRef50_Q9H159 Cluster: Cadherin-19 precursor; n=15;
           Tetrapoda|Rep: Cadherin-19 precursor - Homo sapiens
           (Human)
          Length = 772

 Score =  171 bits (417), Expect = 2e-40
 Identities = 145/505 (28%), Positives = 240/505 (47%), Gaps = 35/505 (6%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F ID R+G +     LDRE+ + Y +  +  D A+  +    S   I V+  D NDN P+
Sbjct: 90  FIIDERTGDIYAIQKLDREERSLYILRAQVIDIATGRAVEPESEFVIKVS--DINDNEPK 147

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDAD---VGANSAIRYAIIGGNTQMQFSIDSLS 206
           F ++ Y   V E     +  ++ ++ A+DAD    G N+ + Y+++ G  Q  FS++  +
Sbjct: 148 FLDEPYEAIVPE--MSPEGTLVIQVTASDADDPSSGNNARLLYSLLQG--QPYFSVEPTT 203

Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDG-GSPSR-SNTTQLLINIRDVNDNAPRFYTSLFQE 264
           G + +   +D E    Y ++I+A+D  G P   S TT +LI + DVNDN P F  SL++ 
Sbjct: 204 GVIRISSKMDRELQDEYWVIIQAKDMIGQPGALSGTTSVLIKLSDVNDNKPIFKESLYRL 263

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
           +VSE+ P G SI  + AYD D G NAE+ Y++ ++D +   D+    + + G V    ++
Sbjct: 264 TVSESAPTGTSIGTIMAYDNDIGENAEMDYSI-EEDDSQTFDIITNHETQEGIVILKKKV 322

Query: 325 DRETQAKYQLLVTATDGGDPPR------SATATXXXXXXXXXXXXXXFMPGQYEVELAED 378
           D E Q  Y +     +   P +       A+ T              F+   Y  E+ E+
Sbjct: 323 DFEHQNHYGIRAKVKNHHVPEQLMKYHTEASTTFIKIQVEDVDEPPLFLLPYYVFEVFEE 382

Query: 379 EPPGTPVVTLTATDAD-EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437
            P G+ V  ++ATD D   + + Y IT      R  + + N  G IT +  LD +    Y
Sbjct: 383 TPQGSFVGVVSATDPDNRKSPIRYSIT------RSKVFNINDNGTITTSNSLDREISAWY 436

Query: 438 VLTVSATDSGGRSDTAMV--QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495
            L+++AT+       + +   + + + N++AP F    Y   V E+A  G  +  +SA D
Sbjct: 437 NLSITATEKYNIEQISSIPLYVQVLNINDHAPEFSQY-YETYVCENAGSGQVIQTISAVD 495

Query: 496 SDVGINAQITY-SLSSE-ISNEAVAHHDQQFVINPQTGAITTNKL-LDRETMSGYLLTVT 552
            D  I     Y +LS E  +N +    D Q      T  I TN+   + +    + +++ 
Sbjct: 496 RDESIEEHHFYFNLSVEDTNNSSFTIIDNQ----DNTAVILTNRTGFNLQEEPVFYISIL 551

Query: 553 ARDGGVPSLSDTTDVEISVVDVNDN 577
             D G+PSL+ T  + I V D  D+
Sbjct: 552 IADNGIPSLTSTNTLTIHVCDCGDS 576



 Score =  156 bits (378), Expect = 9e-36
 Identities = 124/427 (29%), Positives = 201/427 (47%), Gaps = 41/427 (9%)

Query: 391 TDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD-SGG 448
           +D D  +N   Y++ G      F I  + G   I   Q LD ++   Y+L     D + G
Sbjct: 68  SDLDNGNNSFQYKLLGAGAGSTFIIDERTGD--IYAIQKLDREERSLYILRAQVIDIATG 125

Query: 449 RS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD---VGINAQ 503
           R+    +   I ++D N+  P F + PY A V E +P GT V+ V+A+D+D    G NA+
Sbjct: 126 RAVEPESEFVIKVSDINDNEPKFLDEPYEAIVPEMSPEGTLVIQVTASDADDPSSGNNAR 185

Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD--GGVPSL 561
           + YSL               F + P TG I  +  +DRE    Y + + A+D  G   +L
Sbjct: 186 LLYSL---------LQGQPYFSVEPTTGVIRISSKMDRELQDEYWVIIQAKDMIGQPGAL 236

Query: 562 SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621
           S TT V I + DVNDN+P+FK+ LY   + E A  GTS+  + A D D+G N  + Y ++
Sbjct: 237 SGTTSVLIKLSDVNDNKPIFKESLYRLTVSESAPTGTSIGTIMAYDNDIGENAEMDYSIE 296

Query: 622 PKDREEGSFVI--DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ-------SSTVI 672
             D +    +   +   G++   K +D E    + ++A   +   P Q       +ST  
Sbjct: 297 EDDSQTFDIITNHETQEGIVILKKKVDFEHQNHYGIRAKVKNHHVPEQLMKYHTEASTTF 356

Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD-- 730
           + I++ED+ D PP+F      F + E +P G+ +G + A DPD    + + YSI      
Sbjct: 357 IKIQVEDV-DEPPLFLLPYYVFEVFEETPQGSFVGVVSATDPD-NRKSPIRYSITRSKVF 414

Query: 731 DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDN 790
           + N     T   S   E+    +L   +  +KY  + + +S PL+      + V ++ND+
Sbjct: 415 NINDNGTITTSNSLDREISAWYNLSI-TATEKYN-IEQISSIPLY------VQVLNINDH 466

Query: 791 APVMKDF 797
           AP    +
Sbjct: 467 APEFSQY 473



 Score =  147 bits (355), Expect = 6e-33
 Identities = 129/461 (27%), Positives = 210/461 (45%), Gaps = 43/461 (9%)

Query: 311 IDPRSGWVYTSGQLDRETQAKY----QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366
           ID R+G +Y   +LDRE ++ Y    Q++  AT     P S                  F
Sbjct: 92  IDERTGDIYAIQKLDREERSLYILRAQVIDIATGRAVEPESEFVIKVSDINDNEPK---F 148

Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDN-----RLHYEITGGNTRGRFSITSQNGRG 421
           +   YE  + E  P GT V+ +TA+DAD+ +     RL Y +  G     FS+    G  
Sbjct: 149 LDEPYEAIVPEMSPEGTLVIQVTASDADDPSSGNNARLLYSLLQGQPY--FSVEPTTG-- 204

Query: 422 LITVAQPLDFKQERRYVLTVSATDS----GGRSDTAMVQINITDANNYAPVFENAPYTAS 477
           +I ++  +D + +  Y + + A D     G  S T  V I ++D N+  P+F+ + Y  +
Sbjct: 205 VIRISSKMDRELQDEYWVIIQAKDMIGQPGALSGTTSVLIKLSDVNDNKPIFKESLYRLT 264

Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN--EAVAHHDQQFVINPQTGAITT 535
           V E AP GT++  + A D+D+G NA++ YS+  + S   + + +H+ Q       G +  
Sbjct: 265 VSESAPTGTSIGTIMAYDNDIGENAEMDYSIEEDDSQTFDIITNHETQ------EGIVIL 318

Query: 536 NKLLDRETMSGYLLTVTARDGGVPSL-------SDTTDVEISVVDVNDNEPVFKQQLYTA 588
            K +D E  + Y +    ++  VP         + TT ++I V DV D  P+F    Y  
Sbjct: 319 KKKVDFEHQNHYGIRAKVKNHHVPEQLMKYHTEASTTFIKIQVEDV-DEPPLFLLPYYVF 377

Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648
            + E+   G+ V  V ATD D      I Y +    R +   + D  +G I T+ +LDRE
Sbjct: 378 EVFEETPQGSFVGVVSATDPD-NRKSPIRYSIT---RSKVFNIND--NGTITTSNSLDRE 431

Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
             A ++L   A +     Q S++ +++++ +IND  P F S     Y+ EN+  G  I  
Sbjct: 432 ISAWYNLSITATEKYNIEQISSIPLYVQVLNINDHAPEF-SQYYETYVCENAGSGQVIQT 490

Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV 749
           I A D DE       Y     +D+N+ S       D   ++
Sbjct: 491 ISAVDRDESIEEHHFYFNLSVEDTNNSSFTIIDNQDNTAVI 531



 Score =  110 bits (265), Expect = 5e-22
 Identities = 119/476 (25%), Positives = 207/476 (43%), Gaps = 58/476 (12%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVTA 67
           I V D ND+ P F  + YEA V E +  GT V+ + A+D D    G NA + Y++     
Sbjct: 136 IKVSDINDNEPKFLDEPYEAIVPEMSPEGTLVIQVTASDADDPSSGNNARLLYSL----- 190

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
                              Q  F ++  +G +   + +DRE    Y V+++A D      
Sbjct: 191 ----------------LQGQPYFSVEPTTGVIRISSKMDRELQDEYWVIIQAKDMIGQ-P 233

Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
             LS T ++ + + D NDN P F E  Y ++V E  S      I  I A D D+G N+ +
Sbjct: 234 GALSGTTSVLIKLSDVNDNKPIFKESLYRLTVSE--SAPTGTSIGTIMAYDNDIGENAEM 291

Query: 188 RYAIIGGNTQMQFSI----DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP-------S 236
            Y+I   ++Q  F I    ++  G V L K +D+E    Y +  + ++   P       +
Sbjct: 292 DYSIEEDDSQ-TFDIITNHETQEGIVILKKKVDFEHQNHYGIRAKVKNHHVPEQLMKYHT 350

Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
            ++TT + I + DV D  P F    +   V E  P G  +  V A D D    + + Y++
Sbjct: 351 EASTTFIKIQVEDV-DEPPLFLLPYYVFEVFEETPQGSFVGVVSATDPDNR-KSPIRYSI 408

Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
           T +    N++        +G + TS  LDRE  A Y L +TAT+  +  + ++       
Sbjct: 409 T-RSKVFNIN-------DNGTITTSNSLDREISAWYNLSITATEKYNIEQISSIPLYVQV 460

Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNT-RGRF 412
                    F    YE  + E+   G  + T++A D D   E++  ++ ++  +T    F
Sbjct: 461 LNINDHAPEFSQ-YYETYVCENAGSGQVIQTISAVDRDESIEEHHFYFNLSVEDTNNSSF 519

Query: 413 SI--TSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANN 464
           +I     N   ++T     + ++E  + +++   D+G    + T  + I++ D  +
Sbjct: 520 TIIDNQDNTAVILTNRTGFNLQEEPVFYISILIADNGIPSLTSTNTLTIHVCDCGD 575


>UniRef50_UPI0000D57279 Cluster: PREDICTED: similar to CG14900-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG14900-PA - Tribolium castaneum
          Length = 1761

 Score =  170 bits (413), Expect = 5e-40
 Identities = 212/833 (25%), Positives = 354/833 (42%), Gaps = 97/833 (11%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-LKATDQDIGK--NAEVEYTIELVTA 67
           + V D NDH+PVF    Y+ +V E    G T+   ++A+D+D     N++V+Y I     
Sbjct: 123 VYVEDVNDHAPVFVGAPYQLAVDELTPVGLTIFRGIRASDRDKPNTPNSDVQYAI----- 177

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGA-LLTRASLDREKVAR-YTVLVKATDQASP 125
                              +  F +D    A L+ +  LD +   R + + + A+D+  P
Sbjct: 178 --------------ISGNERGKFALDSSQQAFLILKRPLDYDTGDREFLLTIAASDRGIP 223

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIA------KIKATDA 179
                S+  TI + + D++D  P+F++  Y   ++E   +T   +         I A D 
Sbjct: 224 PR---STNTTIRITVNDNDDLSPKFTKGVYRTRINEFYPITGERIHKLLTFDPAIHAFDQ 280

Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-----YRLVIRAQDGGS 234
           D+  ++ IRY II GN +  FS+D ++G + + + +D +  RS     + L I+A    +
Sbjct: 281 DIAIDAPIRYDIIAGNERHIFSLDHVNGSLFIEREIDIDSERSLPGNTFVLQIQASQVDN 340

Query: 235 PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294
           P+++   ++ + I D+NDN P F    +  S+ EN+P G+S++++ A D D+G NAE +Y
Sbjct: 341 PAKTGVARVEVEIMDLNDNLPEFEVDFYNISIVENLPNGFSVLQIIAVDQDQGDNAEFSY 400

Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDG-----GDPPRS 347
            +  +D TG      T+D R+GW+    Q  LDRE ++  ++ V A +           +
Sbjct: 401 QL--EDNTG----AFTLDSRTGWLTVRDQSVLDREKRSTLRMQVYAKEKVPSVVSSKLGA 454

Query: 348 ATATXXXXXXXXXXXXXXFMPGQ-YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEI- 403
           +                 F+P   Y      D   G  V  + A D D   +  + Y I 
Sbjct: 455 SAVNIEVTLLDANDNNPTFIPNNLYNFITNSDLKIGDVVGQIHAIDPDLGRNGIVTYSIQ 514

Query: 404 TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD-----SGGRSDTAMVQIN 458
              N    F +  ++G+  I+V Q +      R++L V A+D     S  RS  A+V I 
Sbjct: 515 KAPNNTVPFKVDPKSGK--ISVNQKV--VTPGRHLLFVEASDQPLNPSERRSSLAVVTIE 570

Query: 459 ITDANNYA-----PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513
           +            P F  APY   V  +  +GT+V  +    +DV     I Y L     
Sbjct: 571 VQQQTGKGTVKGLPDFIGAPYEFWVGGNVGVGTSVGQIRV--ADVPDRRTIIYDLLHSY- 627

Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573
                H    F +  ++G IT    L+      Y       +    +L   T+V I VVD
Sbjct: 628 -----HEGVPFAVEERSGTITVVDNLENYNRQNYEFEAVVTNEKEMTL--VTNVTIHVVD 680

Query: 574 VNDNEPVFKQQLYTANI---MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630
             D + +   +  TA I   +++      + ++G  +A+   +G +    + KD  E   
Sbjct: 681 PKDEKTIL-MKAGTAPIEFHVKENAGNLLIGRLGFKNAN--SSGLVFSIANQKDVTE--H 735

Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVA-IDGGTPPQSSTVIVHIKIEDINDSPPVFES 689
           +   + G + T K LDRE+   + L  +A    G    +    V I ++D ND+ P FE 
Sbjct: 736 ISITSDGSLYTVKPLDRETRDVYRLTVLAEYSKGAITGTGIYQVTIHVDDENDNKPTFEH 795

Query: 690 DCLTFYISENSPIGTTIG---EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746
                 ++EN   GT +     I   D D G N     +I  G+ S  F L+   G    
Sbjct: 796 SKYEGKVTENCISGTEVDLNYLIHVSDKDTGDNGQFGVTI-FGNGSEKFRLDRNTGK--- 851

Query: 747 ELVTMVD--LDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDF 797
              T  D  LD E        ++      L+++  + I+V D NDNAP    F
Sbjct: 852 IFFTSADSPLDREETGIFNLRLVAKDQGGLYDEAILIIMVEDENDNAPTFVQF 904



 Score =  169 bits (412), Expect = 7e-40
 Identities = 154/573 (26%), Positives = 254/573 (44%), Gaps = 63/573 (10%)

Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR-VQAYDADEG-- 287
           D G    +++  + + + DVND+AP F  + +Q +V E  P+G +I R ++A D D+   
Sbjct: 109 DDGEDIITSSLSVTVYVEDVNDHAPVFVGAPYQLAVDELTPVGLTIFRGIRASDRDKPNT 168

Query: 288 VNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET-QAKYQLLVTATDGGDPPR 346
            N+++ Y +   +  G   L  +   +  ++     LD +T   ++ L + A+D G PPR
Sbjct: 169 PNSDVQYAIISGNERGKFALDSS---QQAFLILKRPLDYDTGDREFLLTIAASDRGIPPR 225

Query: 347 SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP----------PGTPVVTLTATDADED 396
           S   T              F  G Y   + E  P             P +     D   D
Sbjct: 226 STNTTIRITVNDNDDLSPKFTKGVYRTRINEFYPITGERIHKLLTFDPAIHAFDQDIAID 285

Query: 397 NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR-----YVLTVSAT--DSGGR 449
             + Y+I  GN R  FS+   NG   + + + +D   ER      +VL + A+  D+  +
Sbjct: 286 APIRYDIIAGNERHIFSLDHVNGS--LFIEREIDIDSERSLPGNTFVLQIQASQVDNPAK 343

Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509
           +  A V++ I D N+  P FE   Y  S+ E+ P G +VL + A D D G NA+ +Y L 
Sbjct: 344 TGVARVEVEIMDLNDNLPEFEVDFYNISIVENLPNGFSVLQIIAVDQDQGDNAEFSYQLE 403

Query: 510 SEISNEAVAHHDQQFVINPQTGAITTN--KLLDRETMSGYLLTVTARDGGVPSL------ 561
                         F ++ +TG +T     +LDRE  S   + V A++  VPS+      
Sbjct: 404 DNTG---------AFTLDSRTGWLTVRDQSVLDREKRSTLRMQVYAKEK-VPSVVSSKLG 453

Query: 562 SDTTDVEISVVDVNDNEPVF-KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620
           +   ++E++++D NDN P F    LY      D  +G  V Q+ A D D+G NG + Y +
Sbjct: 454 ASAVNIEVTLLDANDNNPTFIPNNLYNFITNSDLKIGDVVGQIHAIDPDLGRNGIVTYSI 513

Query: 621 DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP---QSSTVIVHIKI 677
                    F +DP SG I  N+ +   +   H L   A D    P   +SS  +V I++
Sbjct: 514 QKAPNNTVPFKVDPKSGKISVNQKV--VTPGRHLLFVEASDQPLNPSERRSSLAVVTIEV 571

Query: 678 EDINDSP-----PVFESDCLTFYISENSPIGTTIGEIRAHD-PDEGPNAVVHYSIKGGDD 731
           +           P F      F++  N  +GT++G+IR  D PD     +++  +    +
Sbjct: 572 QQQTGKGTVKGLPDFIGAPYEFWVGGNVGVGTSVGQIRVADVPDR--RTIIYDLLHSYHE 629

Query: 732 SNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764
              F++E R G+     +T+VD      R+ YE
Sbjct: 630 GVPFAVEERSGT-----ITVVDNLENYNRQNYE 657



 Score =  149 bits (362), Expect = 8e-34
 Identities = 181/767 (23%), Positives = 328/767 (42%), Gaps = 72/767 (9%)

Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV--GANS 185
           D ++S+ ++ V + D ND+ P F    Y ++VDE ++     +   I+A+D D     NS
Sbjct: 113 DIITSSLSVTVYVEDVNDHAPVFVGAPYQLAVDE-LTPVGLTIFRGIRASDRDKPNTPNS 171

Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVK-TLDYEQ-VRSYRLVIRAQDGGSPSRSNTTQL 243
            ++YAII GN + +F++DS      ++K  LDY+   R + L I A D G P RS  T +
Sbjct: 172 DVQYAIISGNERGKFALDSSQQAFLILKRPLDYDTGDREFLLTIAASDRGIPPRSTNTTI 231

Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPI-GYSIVR-------VQAYDADEGVNAELTYT 295
            I + D +D +P+F   +++  ++E  PI G  I +       + A+D D  ++A + Y 
Sbjct: 232 RITVNDNDDLSPKFTKGVYRTRINEFYPITGERIHKLLTFDPAIHAFDQDIAIDAPIRYD 291

Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK-----YQLLVTATDGGDPPRSATA 350
           +      GN     ++D  +G ++   ++D +++       + L + A+   +P ++  A
Sbjct: 292 I----IAGNERHIFSLDHVNGSLFIEREIDIDSERSLPGNTFVLQIQASQVDNPAKTGVA 347

Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG 410
                          F    Y + + E+ P G  V+ + A D D+ +   +     +  G
Sbjct: 348 RVEVEIMDLNDNLPEFEVDFYNISIVENLPNGFSVLQIIAVDQDQGDNAEFSYQLEDNTG 407

Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTV---------SATDSGGRSDTAMVQINITD 461
            F++ S+   G +TV       +E+R  L +         S   S   +    +++ + D
Sbjct: 408 AFTLDSRT--GWLTVRDQSVLDREKRSTLRMQVYAKEKVPSVVSSKLGASAVNIEVTLLD 465

Query: 462 ANNYAPVF-ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520
           AN+  P F  N  Y      D  IG  V  + A D D+G N  +TYS+    +N      
Sbjct: 466 ANDNNPTFIPNNLYNFITNSDLKIGDVVGQIHAIDPDLGRNGIVTYSIQKAPNNTV---- 521

Query: 521 DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE-- 578
              F ++P++G I+ N+ +   T   +LL V A D  +      + + +  ++V      
Sbjct: 522 --PFKVDPKSGKISVNQKV--VTPGRHLLFVEASDQPLNPSERRSSLAVVTIEVQQQTGK 577

Query: 579 ------PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632
                 P F    Y   +  +  VGTSV Q+    ADV     I Y+L     E   F +
Sbjct: 578 GTVKGLPDFIGAPYEFWVGGNVGVGTSVGQIRV--ADVPDRRTIIYDLLHSYHEGVPFAV 635

Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC- 691
           +  SG I     L+  +   ++ +AV  +       + V +H+ ++  ++   + ++   
Sbjct: 636 EERSGTITVVDNLENYNRQNYEFEAVVTNEKEMTLVTNVTIHV-VDPKDEKTILMKAGTA 694

Query: 692 -LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750
            + F++ EN+     IG +   + +   ++ + +SI    D       T  GS    L T
Sbjct: 695 PIEFHVKENAG-NLLIGRLGFKNAN---SSGLVFSIANQKDVTEHISITSDGS----LYT 746

Query: 751 MVDLDYESPRKKYELVIRA----ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKD 806
           +  LD E+ R  Y L + A     +       +V I V D NDN P  +  +      ++
Sbjct: 747 VKPLDRET-RDVYRLTVLAEYSKGAITGTGIYQVTIHVDDENDNKPTFEHSKYEGKVTEN 805

Query: 807 CF---PVGPFGRVPAYDADVTDKLQYRI-LSGNNANLILLNETTGSM 849
           C     V     +   D D  D  Q+ + + GN +    L+  TG +
Sbjct: 806 CISGTEVDLNYLIHVSDKDTGDNGQFGVTIFGNGSEKFRLDRNTGKI 852



 Score =  144 bits (349), Expect = 3e-32
 Identities = 170/664 (25%), Positives = 280/664 (42%), Gaps = 82/664 (12%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ ++D ND+ P FE+  Y  S+ E   +G +VL + A DQD G NAE  Y +E  T   
Sbjct: 350 EVEIMDLNDNLPEFEVDFYNISIVENLPNGFSVLQIIAVDQDQGDNAEFSYQLEDNTG-- 407

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR--ASLDREKVARYTVLVKATDQA-SPV 126
                               F +D R+G L  R  + LDREK +   + V A ++  S V
Sbjct: 408 -------------------AFTLDSRTGWLTVRDQSVLDREKRSTLRMQVYAKEKVPSVV 448

Query: 127 SDRLSSTA-TIHVNIIDDNDNYPQF-SEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184
           S +L ++A  I V ++D NDN P F     Y    + D+ + D  V+ +I A D D+G N
Sbjct: 449 SSKLGASAVNIEVTLLDANDNNPTFIPNNLYNFITNSDLKIGD--VVGQIHAIDPDLGRN 506

Query: 185 SAIRYAI-IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD---GGSPSRSNT 240
             + Y+I    N  + F +D  SG +S+ + +       + L + A D     S  RS+ 
Sbjct: 507 GIVTYSIQKAPNNTVPFKVDPKSGKISVNQKV--VTPGRHLLFVEASDQPLNPSERRSSL 564

Query: 241 TQLLINIRDVNDNA-----PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295
             + I ++           P F  + ++  V  NV +G S+ +++  D  +     + Y 
Sbjct: 565 AVVTIEVQQQTGKGTVKGLPDFIGAPYEFWVGGNVGVGTSVGQIRVADVPD--RRTIIYD 622

Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355
           +    + G   +P  ++ RSG +     L+   +  Y+     T+  +     T      
Sbjct: 623 LLHSYHEG---VPFAVEERSGTITVVDNLENYNRQNYEFEAVVTNEKE-MTLVTNVTIHV 678

Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITG-GNTRGRFSI 414
                        G   +E    E  G  ++          + L + I    +     SI
Sbjct: 679 VDPKDEKTILMKAGTAPIEFHVKENAGNLLIGRLGFKNANSSGLVFSIANQKDVTEHISI 738

Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDS-GGRSDTAMVQ--INITDANNYAPVFEN 471
           TS    G +   +PLD +    Y LTV A  S G  + T + Q  I++ D N+  P FE+
Sbjct: 739 TSD---GSLYTVKPLDRETRDVYRLTVLAEYSKGAITGTGIYQVTIHVDDENDNKPTFEH 795

Query: 472 APYTASVFEDAPIGTTV---LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528
           + Y   V E+   GT V    ++  +D D G N Q   ++          +  ++F ++ 
Sbjct: 796 SKYEGKVTENCISGTEVDLNYLIHVSDKDTGDNGQFGVTI--------FGNGSEKFRLDR 847

Query: 529 QTGAI---TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585
            TG I   + +  LDRE    + L + A+D G   L D   + I V D NDN P F Q +
Sbjct: 848 NTGKIFFTSADSPLDREETGIFNLRLVAKDQG--GLYDEAILIIMVEDENDNAPTFVQFI 905

Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645
               + ED  +G  V +       +G     H+E   ++  +G++V+ PA    R  KA 
Sbjct: 906 ----VYED--IGAEVEEYDKLGNRIG-----HFE-QLENSTKGTYVLTPA--YTRAKKAK 951

Query: 646 DRES 649
            + S
Sbjct: 952 SKMS 955



 Score =  135 bits (326), Expect = 2e-29
 Identities = 132/438 (30%), Positives = 195/438 (44%), Gaps = 73/438 (16%)

Query: 373  VELAEDEPPGTPVVTLTATDAD-EDNR-LHYE------ITGGNTRGRFSITS----QNGR 420
            V L ED   GTPV+ L A D D  DN  + YE      I    +   F +T         
Sbjct: 958  VVLKEDVGVGTPVIKLVAEDRDFGDNAVVKYEMVSETYIPNEYSAEPFHLTQYFMVHATN 1017

Query: 421  GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480
            G I+V++ L  + E R  L +SA+D GG  D   V++ I D N++ PVF  + Y     E
Sbjct: 1018 GEISVSRTLPPESEFR--LNISASDKGGLKDHISVRLTIEDVNDHPPVFSKSWYNFDAEE 1075

Query: 481  DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
             +     +  V A D D G NA ITY +  +            F I PQ G +T + +LD
Sbjct: 1076 ASYSRNIIGRVEAIDGDFGPNANITYKIQEK-------DPKLPFAITPQGGVLTIDGVLD 1128

Query: 541  RETMSGYLLTVTARDGGV--PSLSDTTDVEISVVDVNDNEPVF----------------- 581
            RET   Y   V A+D      SLS   +VE++V+DVNDN P F                 
Sbjct: 1129 RETKDKYNFVVVAKDNPTKGESLSSFVNVEVNVLDVNDNPPSFYGYDDLLPNPESNTYSN 1188

Query: 582  --KQQ---LYTANIMEDALVGTSVSQVGATDADV--GLNGRIHYELDPKDREEGSFVIDP 634
               Q+   +Y A + E++ +GT V+++ A D+D     NG + +++  K   +  F ID 
Sbjct: 1189 HNYQEDIPVYYATVAENSPIGTPVTRIFANDSDFTGNGNGLLLFDIPYKKNRQNLFTIDS 1248

Query: 635  ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND-----SPPVFES 689
              G++ T   LD E+   H++  VA D G+P  SST ++ + + D+ +       PVF  
Sbjct: 1249 KEGIVTTIGKLDFENQNMHNITIVASDLGSPSLSSTALLVVTVIDVPEDLQSMEHPVFAH 1308

Query: 690  DCLTFYISENSPI-------------------GTTIGEIRAHDPDEGPNAVVHYSIKGGD 730
                  + EN P+                   G  I  ++A DPD G N  V Y I G  
Sbjct: 1309 RYYEVEVEENVPVPLKVLTLNVTESYSTTASYGHHIVRLQAKDPDLGLNGEVRYQILGRA 1368

Query: 731  D--SNSFSLETRQGSDKA 746
            D  +  F+++   G  +A
Sbjct: 1369 DEAARRFTIDPITGQVRA 1386



 Score =  123 bits (296), Expect = 8e-26
 Identities = 104/350 (29%), Positives = 169/350 (48%), Gaps = 43/350 (12%)

Query: 480  EDAPIGTTVLVVSATDSDVGINAQITYSLSSE--ISNEAVA---HHDQQFVINPQTGAIT 534
            ED  +GT V+ + A D D G NA + Y + SE  I NE  A   H  Q F+++   G I+
Sbjct: 962  EDVGVGTPVIKLVAEDRDFGDNAVVKYEMVSETYIPNEYSAEPFHLTQYFMVHATNGEIS 1021

Query: 535  TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594
             ++ L  E  S + L ++A D G   L D   V +++ DVND+ PVF +  Y  +  E +
Sbjct: 1022 VSRTLPPE--SEFRLNISASDKG--GLKDHISVRLTIEDVNDHPPVFSKSWYNFDAEEAS 1077

Query: 595  LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654
                 + +V A D D G N  I Y++  KD  +  F I P  GV+  +  LDRE+   ++
Sbjct: 1078 YSRNIIGRVEAIDGDFGPNANITYKIQEKD-PKLPFAITPQGGVLTIDGVLDRETKDKYN 1136

Query: 655  LKAVAIDGGTPPQ--SSTVIVHIKIEDINDSPPVF--------------------ESDCL 692
               VA D  T  +  SS V V + + D+ND+PP F                    + D  
Sbjct: 1137 FVVVAKDNPTKGESLSSFVNVEVNVLDVNDNPPSFYGYDDLLPNPESNTYSNHNYQEDIP 1196

Query: 693  TFY--ISENSPIGTTIGEIRAHDPD--EGPNAVVHYSIK-GGDDSNSFSLETRQGSDKAE 747
             +Y  ++ENSPIGT +  I A+D D     N ++ + I    +  N F++++++G     
Sbjct: 1197 VYYATVAENSPIGTPVTRIFANDSDFTGNGNGLLLFDIPYKKNRQNLFTIDSKEGI---- 1252

Query: 748  LVTMVDLDYESPRKKYELVIRA--ASPPLWNDVRVEILVTDVNDNAPVMK 795
            + T+  LD+E+       ++ +   SP L +   + + V DV ++   M+
Sbjct: 1253 VTTIGKLDFENQNMHNITIVASDLGSPSLSSTALLVVTVIDVPEDLQSME 1302



 Score =  118 bits (284), Expect = 2e-24
 Identities = 110/391 (28%), Positives = 175/391 (44%), Gaps = 46/391 (11%)

Query: 32   VREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFR 91
            ++E    GT V+ L A D+D G NA V+Y  E+V+ +T  P +           +   F 
Sbjct: 960  LKEDVGVGTPVIKLVAEDRDFGDNAVVKY--EMVS-ETYIPNE----YSAEPFHLTQYFM 1012

Query: 92   IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151
            +   +G +    +L  E  + + + + A+D+   + D +S   TI     D ND+ P FS
Sbjct: 1013 VHATNGEISVSRTLPPE--SEFRLNISASDKGG-LKDHISVRLTIE----DVNDHPPVFS 1065

Query: 152  EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSL 211
            +  Y    +E  S + N +I +++A D D G N+ I Y I   + ++ F+I    G +++
Sbjct: 1066 KSWYNFDAEE-ASYSRN-IIGRVEAIDGDFGPNANITYKIQEKDPKLPFAITPQGGVLTI 1123

Query: 212  VKTLDYEQVRSYRLVIRAQDGGS--PSRSNTTQLLINIRDVNDNAPRFY----------- 258
               LD E    Y  V+ A+D  +   S S+   + +N+ DVNDN P FY           
Sbjct: 1124 DGVLDRETKDKYNFVVVAKDNPTKGESLSSFVNVEVNVLDVNDNPPSFYGYDDLLPNPES 1183

Query: 259  -----------TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
                         ++  +V+EN PIG  + R+ A D+D   N      + D  Y  N   
Sbjct: 1184 NTYSNHNYQEDIPVYYATVAENSPIGTPVTRIFANDSDFTGNGN-GLLLFDIPYKKNRQN 1242

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX-----XXXXXXX 362
              TID + G V T G+LD E Q  + + + A+D G P  S+TA                 
Sbjct: 1243 LFTIDSKEGIVTTIGKLDFENQNMHNITIVASDLGSPSLSSTALLVVTVIDVPEDLQSME 1302

Query: 363  XXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393
               F    YEVE+ E+ P    V+TL  T++
Sbjct: 1303 HPVFAHRYYEVEVEENVPVPLKVLTLNVTES 1333



 Score =  111 bits (266), Expect = 4e-22
 Identities = 115/393 (29%), Positives = 167/393 (42%), Gaps = 71/393 (18%)

Query: 7    IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
            I  ++ + D NDH PVF    Y     E + S   +  ++A D D G NA + Y I+   
Sbjct: 1048 ISVRLTIEDVNDHPPVFSKSWYNFDAEEASYSRNIIGRVEAIDGDFGPNANITYKIQ--E 1105

Query: 67   ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
             D   P                 F I  + G L     LDRE   +Y  +V A D  +  
Sbjct: 1106 KDPKLP-----------------FAITPQGGVLTIDGVLDRETKDKYNFVVVAKDNPTK- 1147

Query: 127  SDRLSSTATIHVNIIDDNDNYPQF----------SEKTYTV-SVDEDISV------TDNP 169
             + LSS   + VN++D NDN P F             TY+  +  EDI V       ++P
Sbjct: 1148 GESLSSFVNVEVNVLDVNDNPPSFYGYDDLLPNPESNTYSNHNYQEDIPVYYATVAENSP 1207

Query: 170  V---IAKIKATDADV--GANSAIRYAI-IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY 223
            +   + +I A D+D     N  + + I    N Q  F+IDS  G V+ +  LD+E    +
Sbjct: 1208 IGTPVTRIFANDSDFTGNGNGLLLFDIPYKKNRQNLFTIDSKEGIVTTIGKLDFENQNMH 1267

Query: 224  RLVIRAQDGGSPSRSNTTQLLINIRDVNDNA-----PRFYTSLFQESVSENVPI------ 272
             + I A D GSPS S+T  L++ + DV ++      P F    ++  V ENVP+      
Sbjct: 1268 NITIVASDLGSPSLSSTALLVVTVIDVPEDLQSMEHPVFAHRYYEVEVEENVPVPLKVLT 1327

Query: 273  -------------GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319
                         G+ IVR+QA D D G+N E+ Y +  +          TIDP +G V 
Sbjct: 1328 LNVTESYSTTASYGHHIVRLQAKDPDLGLNGEVRYQILGR--ADEAARRFTIDPITGQVR 1385

Query: 320  TSGQLDRETQAKYQLLVTATD--GGDPPRSATA 350
                  R+    Y   V ATD  G D  +S+ A
Sbjct: 1386 AIANFARDAGKVYGFDVKATDRRGADDGKSSIA 1418



 Score = 94.7 bits (225), Expect = 3e-17
 Identities = 122/477 (25%), Positives = 201/477 (42%), Gaps = 73/477 (15%)

Query: 266  VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN--------VDLPITIDPRSGW 317
            + E+V +G  ++++ A D D G NA + Y M  + Y  N        +     +   +G 
Sbjct: 960  LKEDVGVGTPVIKLVAEDRDFGDNAVVKYEMVSETYIPNEYSAEPFHLTQYFMVHATNGE 1019

Query: 318  VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377
            +  S  L  E++  ++L ++A+D G      +                F    Y  +  E
Sbjct: 1020 ISVSRTLPPESE--FRLNISASDKGGLKDHISVRLTIEDVNDHPPV--FSKSWYNFDAEE 1075

Query: 378  DEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435
                   +  + A D D   +  + Y+I   + +  F+IT Q G  ++T+   LD + + 
Sbjct: 1076 ASYSRNIIGRVEAIDGDFGPNANITYKIQEKDPKLPFAITPQGG--VLTIDGVLDRETKD 1133

Query: 436  RYVLTVSATDSGGRSDTAM----VQINITDANNYAPVF---------------------E 470
            +Y   V A D+  + ++      V++N+ D N+  P F                     E
Sbjct: 1134 KYNFVVVAKDNPTKGESLSSFVNVEVNVLDVNDNPPSFYGYDDLLPNPESNTYSNHNYQE 1193

Query: 471  NAP-YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529
            + P Y A+V E++PIGT V  + A DSD   N      L  +I  +   +    F I+ +
Sbjct: 1194 DIPVYYATVAENSPIGTPVTRIFANDSDFTGNGNGL--LLFDIPYKK--NRQNLFTIDSK 1249

Query: 530  TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN-----EPVFKQQ 584
             G +TT   LD E  + + +T+ A D G PSLS T  + ++V+DV ++      PVF  +
Sbjct: 1250 EGIVTTIGKLDFENQNMHNITIVASDLGSPSLSSTALLVVTVIDVPEDLQSMEHPVFAHR 1309

Query: 585  LY---------------TANIMED----ALVGTSVSQVGATDADVGLNGRIHYE-LDPKD 624
             Y               T N+ E     A  G  + ++ A D D+GLNG + Y+ L   D
Sbjct: 1310 YYEVEVEENVPVPLKVLTLNVTESYSTTASYGHHIVRLQAKDPDLGLNGEVRYQILGRAD 1369

Query: 625  REEGSFVIDPASGVIR--TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679
                 F IDP +G +R   N A D   V   D+KA    G    +SS   V + + D
Sbjct: 1370 EAARRFTIDPITGQVRAIANFARDAGKVYGFDVKATDRRGADDGKSSIANVFVYVLD 1426



 Score = 92.3 bits (219), Expect = 2e-16
 Identities = 89/334 (26%), Positives = 148/334 (44%), Gaps = 23/334 (6%)

Query: 555 DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ-VGATDADVGL- 612
           D G   ++ +  V + V DVND+ PVF    Y   + E   VG ++ + + A+D D    
Sbjct: 109 DDGEDIITSSLSVTVYVEDVNDHAPVFVGAPYQLAVDELTPVGLTIFRGIRASDRDKPNT 168

Query: 613 -NGRIHYELDPKDREEGSFVIDPAS-GVIRTNKALDRESVATHDLKAVAI-DGGTPPQSS 669
            N  + Y +     E G F +D +    +   + LD ++     L  +A  D G PP+S+
Sbjct: 169 PNSDVQYAII-SGNERGKFALDSSQQAFLILKRPLDYDTGDREFLLTIAASDRGIPPRST 227

Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPI-GTTIGEIRAHDP-------DEGPNAV 721
              + I + D +D  P F        I+E  PI G  I ++   DP       D   +A 
Sbjct: 228 NTTIRITVNDNDDLSPKFTKGVYRTRINEFYPITGERIHKLLTFDPAIHAFDQDIAIDAP 287

Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDV 778
           + Y I  G++ + FSL+   GS   E    +D +   P   + L I+A+   +P      
Sbjct: 288 IRYDIIAGNERHIFSLDHVNGSLFIEREIDIDSERSLPGNTFVLQIQASQVDNPAKTGVA 347

Query: 779 RVEILVTDVNDNAPVMKDFQIIFNNYK--DCFPVG-PFGRVPAYDADVTDKLQYRILSGN 835
           RVE+ + D+NDN P   +F++ F N    +  P G    ++ A D D  D  ++     +
Sbjct: 348 RVEVEIMDLNDNLP---EFEVDFYNISIVENLPNGFSVLQIIAVDQDQGDNAEFSYQLED 404

Query: 836 NANLILLNETTGSMTLSPQLNTNVPKLATMEVSV 869
           N     L+  TG +T+  Q   +  K +T+ + V
Sbjct: 405 NTGAFTLDSRTGWLTVRDQSVLDREKRSTLRMQV 438



 Score = 83.4 bits (197), Expect = 8e-14
 Identities = 66/202 (32%), Positives = 97/202 (48%), Gaps = 22/202 (10%)

Query: 151  SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG------------NTQM 198
            S+ +  V + ED+ V   PVI K+ A D D G N+ ++Y ++              +   
Sbjct: 952  SKMSPLVVLKEDVGV-GTPVI-KLVAEDRDFGDNAVVKYEMVSETYIPNEYSAEPFHLTQ 1009

Query: 199  QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY 258
             F + + +G++S+ +TL  E    +RL I A D G      + +L   I DVND+ P F 
Sbjct: 1010 YFMVHATNGEISVSRTLPPES--EFRLNISASDKGGLKDHISVRL--TIEDVNDHPPVFS 1065

Query: 259  TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV 318
             S +     E       I RV+A D D G NA +TY + +KD      LP  I P+ G +
Sbjct: 1066 KSWYNFDAEEASYSRNIIGRVEAIDGDFGPNANITYKIQEKD----PKLPFAITPQGGVL 1121

Query: 319  YTSGQLDRETQAKYQLLVTATD 340
               G LDRET+ KY  +V A D
Sbjct: 1122 TIDGVLDRETKDKYNFVVVAKD 1143



 Score = 78.2 bits (184), Expect = 3e-12
 Identities = 74/232 (31%), Positives = 103/232 (44%), Gaps = 29/232 (12%)

Query: 590  IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP-----------ASGV 638
            + ED  VGT V ++ A D D G N  + YE+  +      +  +P            +G 
Sbjct: 960  LKEDVGVGTPVIKLVAEDRDFGDNAVVKYEMVSETYIPNEYSAEPFHLTQYFMVHATNGE 1019

Query: 639  IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698
            I  ++ L  ES    ++ A +  GG     S   V + IED+ND PPVF      F   E
Sbjct: 1020 ISVSRTLPPESEFRLNISA-SDKGGLKDHIS---VRLTIEDVNDHPPVFSKSWYNFDAEE 1075

Query: 699  NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD--LDY 756
             S     IG + A D D GPNA + Y I+  D    F++ T QG      V  +D  LD 
Sbjct: 1076 ASYSRNIIGRVEAIDGDFGPNANITYKIQEKDPKLPFAI-TPQGG-----VLTIDGVLDR 1129

Query: 757  ESPRKKYELVIRAASPP-----LWNDVRVEILVTDVNDNAPVMKDFQIIFNN 803
            E+ + KY  V+ A   P     L + V VE+ V DVNDN P    +  +  N
Sbjct: 1130 ET-KDKYNFVVVAKDNPTKGESLSSFVNVEVNVLDVNDNPPSFYGYDDLLPN 1180



 Score = 64.1 bits (149), Expect = 5e-08
 Identities = 66/278 (23%), Positives = 121/278 (43%), Gaps = 41/278 (14%)

Query: 7    IHQQINVLDCNDHSPVFE-----MQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61
            ++ ++NVLD ND+ P F      +   E++     +    +    AT   + +N+ +   
Sbjct: 1155 VNVEVNVLDVNDNPPSFYGYDDLLPNPESNTYSNHNYQEDIPVYYAT---VAENSPIGTP 1211

Query: 62   IELVTAD----TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLV 117
            +  + A+    T N               Q++F ID + G + T   LD E    + + +
Sbjct: 1212 VTRIFANDSDFTGNGNGLLLFDIPYKKNRQNLFTIDSKEGIVTTIGKLDFENQNMHNITI 1271

Query: 118  KATDQASPVSDRLSSTATIHVNIIDDNDN-----YPQFSEKTYTVSVDEDISV-----TD 167
             A+D  SP    LSSTA + V +ID  ++     +P F+ + Y V V+E++ V     T 
Sbjct: 1272 VASDLGSP---SLSSTALLVVTVIDVPEDLQSMEHPVFAHRYYEVEVEENVPVPLKVLTL 1328

Query: 168  NPV------------IAKIKATDADVGANSAIRYAIIG--GNTQMQFSIDSLSGDVSLVK 213
            N              I +++A D D+G N  +RY I+G       +F+ID ++G V  + 
Sbjct: 1329 NVTESYSTTASYGHHIVRLQAKDPDLGLNGEVRYQILGRADEAARRFTIDPITGQVRAIA 1388

Query: 214  TLDYEQVRSYRLVIRAQD--GGSPSRSNTTQLLINIRD 249
                +  + Y   ++A D  G    +S+   + + + D
Sbjct: 1389 NFARDAGKVYGFDVKATDRRGADDGKSSIANVFVYVLD 1426



 Score = 37.5 bits (83), Expect = 5.3
 Identities = 36/126 (28%), Positives = 50/126 (39%), Gaps = 5/126 (3%)

Query: 21   PVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT---LNPEDAXX 77
            PVF  + YE  V E       VLTL  T+      +   + + L   D    LN E    
Sbjct: 1304 PVFAHRYYEVEVEENVPVPLKVLTLNVTESYSTTASYGHHIVRLQAKDPDLGLNGEVRYQ 1363

Query: 78   XXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIH 137
                     +  F ID  +G +   A+  R+    Y   VKATD+     D  SS A + 
Sbjct: 1364 ILGRADEAARR-FTIDPITGQVRAIANFARDAGKVYGFDVKATDRRG-ADDGKSSIANVF 1421

Query: 138  VNIIDD 143
            V ++DD
Sbjct: 1422 VYVLDD 1427


>UniRef50_Q7UY44 Cluster: Fat protein-possibly involved in cell-cell
            attachment; n=1; Pirellula sp.|Rep: Fat protein-possibly
            involved in cell-cell attachment - Rhodopirellula baltica
          Length = 2009

 Score =  169 bits (412), Expect = 7e-40
 Identities = 199/807 (24%), Positives = 329/807 (40%), Gaps = 65/807 (8%)

Query: 37   SSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQD--VFRIDG 94
            S+      +   + D+ +NA++  T+  ++    N  D+            D   F IDG
Sbjct: 905  STNVAPTAIAIDNNDVEENADIGTTVGTLSTTDANTMDSFVYTLVSGTGDTDNASFAIDG 964

Query: 95   RSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKT 154
             +  L+T ASLD E  + Y+V +++TD        LS+  T  +   + ND     +   
Sbjct: 965  NN--LVTAASLDFETQSSYSVRIQSTDPFG-----LSTVETFTITATNVNDAPTAIAIDN 1017

Query: 155  YTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD-VSLVK 213
             T++ D     T    +     TD D  A+    YA++ G+     +  ++SG+ +    
Sbjct: 1018 STIAEDTASGTT----VGSFTTTDDD--ASDTFTYALVSGDGDTDNAAFTISGNNLVTAT 1071

Query: 214  TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIG 273
            T D+E   SY   IR Q   S   +    L I + D N+       SL   S+SE+   G
Sbjct: 1072 TFDFETQSSYS--IRVQTTDSAGATFEQVLTITVTDTNEVPTAI--SLDNSSISEDAASG 1127

Query: 274  YSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD-LPITIDPRSGWVYTSGQLDRETQAKY 332
             ++      DAD   +   TYT+   +  G+ D    TI    G + T+   D +TQ+ Y
Sbjct: 1128 TTVGAFSTTDAD--ASDTFTYTLVSGE--GDTDNAAFTIS--GGNLVTATTFDFDTQSSY 1181

Query: 333  QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392
             + V   D          T                    ++E  E    GT V +L+ TD
Sbjct: 1182 SIRVQTEDSAGATFEQVLTITITENEANQTPTAISIDNTDIE--EHATVGTTVGSLSTTD 1239

Query: 393  ADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT 452
            A+  +   Y +  G      +  + +G  L+T A   DF+ +  Y + V  TDSGG +  
Sbjct: 1240 ANASDTFTYALVSGEGDTDNAAFTISGSNLVT-ATTFDFETQSSYSIRVQTTDSGGATFE 1298

Query: 453  AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512
             ++ ++ITD+N+ AP    A   A++ ED   GT V  +S TD+D G     TY+L   +
Sbjct: 1299 QILTLSITDSND-APT-SLAIDNATISEDVASGTVVGALSTTDADAG--DTFTYAL---V 1351

Query: 513  SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572
            S E     +  F I+     + T    D +T S Y + V + D    +++    + I+  
Sbjct: 1352 SGEGDT-DNAAFSIDGSN--LVTATTFDFDTQSSYSVRVQSTDSAGATITQVLTITIT-- 1406

Query: 573  DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632
                N       +    I ED   GT V  +  TDAD G            D +  +F I
Sbjct: 1407 --GTNAVPTAIAIDNDTIAEDVASGTVVGALSTTDADAGDTFTYALVSGDGDTDNAAFTI 1464

Query: 633  DPASGVIRTNKALDRESVATHDLKAVAID--GGTPPQSSTVIVHIKIEDINDSPPVFESD 690
            D ++ V  T    D E+  ++ ++    D  G T  Q    ++ I + D+N++P     D
Sbjct: 1465 DGSNLVTAT--TFDFETQDSYSVRVQTTDSAGATFEQ----VLTISVTDVNETPTAIAID 1518

Query: 691  CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750
                 ++E+   GT +G +   D D G      Y++  GD     +  T  GS+   LVT
Sbjct: 1519 --NSSVAEDVASGTVVGALSTTDADAGDTFT--YALVSGDGDTDNASFTIDGSN---LVT 1571

Query: 751  MVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCF 808
                D+E+       V    S     +  + I +TDVN+ AP  +     ++  +     
Sbjct: 1572 ATTFDFETQDSYSVRVQTTDSDGATFEQTLTISITDVNE-APTAISISSSVVTEDSTSGT 1630

Query: 809  PVGPFGRVPAYDADVTDKLQYRILSGN 835
             VG F      D D +D   Y +++G+
Sbjct: 1631 TVGSFSTT---DVDASDTFTYTLVAGD 1654



 Score =  167 bits (406), Expect = 4e-39
 Identities = 205/851 (24%), Positives = 336/851 (39%), Gaps = 78/851 (9%)

Query: 30   ASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDV 89
            +++ E  +SGTTV +   TD D    A   +T  LV+ D  + ++A              
Sbjct: 1018 STIAEDTASGTTVGSFTTTDDD----ASDTFTYALVSGDG-DTDNAA------------- 1059

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
            F I G +  L+T  + D E  + Y++ V+ TD A    +++     + + + D N+    
Sbjct: 1060 FTISGNN--LVTATTFDFETQSSYSIRVQTTDSAGATFEQV-----LTITVTDTNEVPTA 1112

Query: 150  FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG-D 208
             S    ++S D     T    +     TDAD  A+    Y ++ G      +  ++SG +
Sbjct: 1113 ISLDNSSISEDAASGTT----VGAFSTTDAD--ASDTFTYTLVSGEGDTDNAAFTISGGN 1166

Query: 209  VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268
            +    T D++   SY + ++ +D    +      + I   + N        S+    + E
Sbjct: 1167 LVTATTFDFDTQSSYSIRVQTEDSAGATFEQVLTITITENEANQTPTAI--SIDNTDIEE 1224

Query: 269  NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328
            +  +G ++  +   DA    NA  T+T       G+ D        S  V T+   D ET
Sbjct: 1225 HATVGTTVGSLSTTDA----NASDTFTYALVSGEGDTDNAAFTISGSNLV-TATTFDFET 1279

Query: 329  QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388
            Q+ Y + V  TD G        T                       ++ED   GT V  L
Sbjct: 1280 QSSYSIRVQTTDSGGATFEQILTLSITDSNDAPTSLAID----NATISEDVASGTVVGAL 1335

Query: 389  TATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG 448
            + TDAD  +   Y +  G      +  S +G  L+T A   DF  +  Y + V +TDS G
Sbjct: 1336 STTDADAGDTFTYALVSGEGDTDNAAFSIDGSNLVT-ATTFDFDTQSSYSVRVQSTDSAG 1394

Query: 449  RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508
             + T ++ I IT  N        A    ++ ED   GT V  +S TD+D G     TY+L
Sbjct: 1395 ATITQVLTITITGTNAVPTAI--AIDNDTIAEDVASGTVVGALSTTDADAGDT--FTYAL 1450

Query: 509  SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568
             S   +   A     F I+     + T    D ET   Y + V   D    +      + 
Sbjct: 1451 VSGDGDTDNA----AFTIDGSN--LVTATTFDFETQDSYSVRVQTTDSAGATFEQV--LT 1502

Query: 569  ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG 628
            ISV DVN+        +  +++ ED   GT V  +  TDAD G            D +  
Sbjct: 1503 ISVTDVNETPTAIA--IDNSSVAEDVASGTVVGALSTTDADAGDTFTYALVSGDGDTDNA 1560

Query: 629  SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688
            SF ID ++ V  T    + +   +  ++    DG T  Q+ T    I I D+N++P    
Sbjct: 1561 SFTIDGSNLVTATTFDFETQDSYSVRVQTTDSDGATFEQTLT----ISITDVNEAPTAIS 1616

Query: 689  SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAEL 748
                +  ++E+S  GTT+G     D D        Y++  GD     +  T  G +   L
Sbjct: 1617 IS--SSVVTEDSTSGTTVGSFSTTDVDASDTFT--YTLVAGDGDTDNASFTIDGGN---L 1669

Query: 749  VTMVDLDYESPRKKYELVIRAASPP-LWNDVRVEILVTDVNDNAP--VMKDFQIIFNNYK 805
            VT   LD ++ +  Y + +R+      + +    I VT+ N +AP  +  D   I  N  
Sbjct: 1670 VTATTLDMDT-QSSYSIRVRSTDAGGSFVEQTFTITVTETN-SAPTAIALDDATIAENAA 1727

Query: 806  DCFPVGPFGRVPAYDADVTDKLQYRILSG-NNANLILLNETTGSMTLSPQLNTNVPKLAT 864
                VG        DADV D   Y ++SG  + +  L     G++  +   +       +
Sbjct: 1728 IGTVVGALSTT---DADVADTFTYSLVSGVGDTDNALFAIDGGNLVTAATFDFETQSSYS 1784

Query: 865  MEVSVTDGVNE 875
            + +  +D V E
Sbjct: 1785 VRIQSSDAVGE 1795



 Score =  150 bits (364), Expect = 5e-34
 Identities = 185/730 (25%), Positives = 301/730 (41%), Gaps = 71/730 (9%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            +++ D ND      +    A++ E  +SGT V  L  TD D G      +T  LV+ +  
Sbjct: 1303 LSITDSNDAPTSLAIDN--ATISEDVASGTVVGALSTTDADAGDT----FTYALVSGEG- 1355

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            + ++A              F IDG +  L+T  + D +  + Y+V V++TD A       
Sbjct: 1356 DTDNAA-------------FSIDGSN--LVTATTFDFDTQSSYSVRVQSTDSAGA----- 1395

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            + T  + + I   N      +    T++ D    V    V+  +  TDAD G      YA
Sbjct: 1396 TITQVLTITITGTNAVPTAIAIDNDTIAED----VASGTVVGALSTTDADAG--DTFTYA 1449

Query: 191  IIGGNTQMQFSIDSLSG-DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
            ++ G+     +  ++ G ++    T D+E   SY   +R Q   S   +    L I++ D
Sbjct: 1450 LVSGDGDTDNAAFTIDGSNLVTATTFDFETQDSYS--VRVQTTDSAGATFEQVLTISVTD 1507

Query: 250  VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD-LP 308
            VN+       ++   SV+E+V  G  +  +   DAD G     TY +   D  G+ D   
Sbjct: 1508 VNETPTAI--AIDNSSVAEDVASGTVVGALSTTDADAGDT--FTYALVSGD--GDTDNAS 1561

Query: 309  ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368
             TID  +  + T+   D ETQ  Y + V  TD        T T                 
Sbjct: 1562 FTIDGSN--LVTATTFDFETQDSYSVRVQTTDSDGATFEQTLTISITDVNEAPTAISISS 1619

Query: 369  GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428
                  + ED   GT V + + TD D  +   Y +  G+     +  + +G  L+T A  
Sbjct: 1620 SV----VTEDSTSGTTVGSFSTTDVDASDTFTYTLVAGDGDTDNASFTIDGGNLVT-ATT 1674

Query: 429  LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
            LD   +  Y + V +TD+GG        I +T+ N+ AP    A   A++ E+A IGT V
Sbjct: 1675 LDMDTQSSYSIRVRSTDAGGSFVEQTFTITVTETNS-APT-AIALDDATIAENAAIGTVV 1732

Query: 489  LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
              +S TD+DV      TYSL S + +      +  F I+   G + T    D ET S Y 
Sbjct: 1733 GALSTTDADVA--DTFTYSLVSGVGDT----DNALFAID--GGNLVTAATFDFETQSSYS 1784

Query: 549  LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
            + + + D    ++S +    I+VVD+ND  P      + A I      G  V  +GA D 
Sbjct: 1785 VRIQSSDAVGETVSQS--FVITVVDIND-APTGLTLPFPA-IASGQASGFLVGNLGAEDQ 1840

Query: 609  DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
            D G      +     D +   F +    G +RT +A D    A + ++    D       
Sbjct: 1841 DAGDTFTFEFVSGEGDLDNDKFTL--VDGALRTAEATDDAIQALYSIRVRVTDSDGLTFE 1898

Query: 669  STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728
             T  + +  E++  +P     D  T  +++ +  GTT+G   A D ++       +    
Sbjct: 1899 DTADLIVTEENV--APTAILLDATT--VADGAASGTTVGTFTATDANDFDEHTFEFVAGE 1954

Query: 729  GD-DSNSFSL 737
            GD D+ SF++
Sbjct: 1955 GDTDNASFTI 1964



 Score =  139 bits (336), Expect = 1e-30
 Identities = 199/801 (24%), Positives = 314/801 (39%), Gaps = 73/801 (9%)

Query: 45   LKATDQDIGKNAEVEYTI-ELVTADTLNPEDAXXXXXXXXXXVQDV-FRIDGRSGALLTR 102
            +  +D  I +N     ++ +L T D+   +              D  F I G S  L+  
Sbjct: 515  ISLSDTSIAENEAASTSVGDLSTTDSNTGDTFTYSIVSIDGSTTDTTFAISGNS--LVAT 572

Query: 103  ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162
             SLD E  + YTV+V+ TDQ       LS   T  +N+ D N       E    +++ +D
Sbjct: 573  ESLDFETKSSYTVVVRTTDQGG-----LSFDQTFTINVDDIN-------EAPTAIALSDD 620

Query: 163  ISVTDNPVIAKI--KATDADVGANSAIRYAIIGGNTQM-QFSIDSLSGDVSLVKTLDYEQ 219
             SV D+ V   +    T  DV A+    YA++ G       S   +  ++    T+D++ 
Sbjct: 621  -SVADDSVSGTVVGSFTTTDVDASDTFTYALVSGTGDTDNASFTIVGNELRTATTIDFDT 679

Query: 220  VRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRV 279
              SY + I+  D G      T + +  I  V  N      SL   +V+EN   G ++   
Sbjct: 680  QSSYSIRIQTTDSG----GETFEQVFTI--VQSNEGPTAISLSDSTVAENGSAGDTVGTF 733

Query: 280  QAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTAT 339
             + D   G     T+   + D   N    I  D     + T+G LD ETQ    + V +T
Sbjct: 734  SSTDPTSGDTFTYTFVTGEGD-DDNALFQIDGDE----LQTAGSLDAETQGTLTIRVRST 788

Query: 340  DGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRL 399
            D        T T               + G +   +A  EP GT V TL   D D  + +
Sbjct: 789  DSTGEFTEETFTITVSSVNEAPTTIT-LSGTH---VATGEPSGTTVGTLGTDDPDSGDTI 844

Query: 400  HYE-ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN 458
             Y  ++G       S T  NG  L+T A   + + +  Y + V A D+ G S      I 
Sbjct: 845  TYTLVSGTGDTDNASFTISNGE-LVT-AFAANQQTQSSYSVRVRAQDADGLSTEETFTIT 902

Query: 459  ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518
            IT + N AP    A     V E+A IGTTV  +S TD++        Y+L S   +    
Sbjct: 903  IT-STNVAPT-AIAIDNNDVEENADIGTTVGTLSTTDANT--MDSFVYTLVSGTGDT--- 955

Query: 519  HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578
              +  F I+     + T   LD ET S Y + + + D     LS      I+  +VND  
Sbjct: 956  -DNASFAIDGNN--LVTAASLDFETQSSYSVRIQSTDPF--GLSTVETFTITATNVNDAP 1010

Query: 579  PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638
                  +  + I ED   GT+V     TD D   +    Y L   D +  +     +   
Sbjct: 1011 TAI--AIDNSTIAEDTASGTTVGSFTTTDDDA--SDTFTYALVSGDGDTDNAAFTISGNN 1066

Query: 639  IRTNKALDRESVATHDLKAVAID--GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696
            + T    D E+ +++ ++    D  G T  Q    ++ I + D N+ P     D     I
Sbjct: 1067 LVTATTFDFETQSSYSIRVQTTDSAGATFEQ----VLTITVTDTNEVPTAISLD--NSSI 1120

Query: 697  SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756
            SE++  GTT+G     D D        Y++  G+     +  T  G +   LVT    D+
Sbjct: 1121 SEDAASGTTVGAFSTTDADASDTFT--YTLVSGEGDTDNAAFTISGGN---LVTATTFDF 1175

Query: 757  ESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN--YKDCFPVG-PF 813
            ++ +  Y   IR  +         ++L   + +N        I  +N   ++   VG   
Sbjct: 1176 DT-QSSYS--IRVQTEDSAGATFEQVLTITITENEANQTPTAISIDNTDIEEHATVGTTV 1232

Query: 814  GRVPAYDADVTDKLQYRILSG 834
            G +   DA+ +D   Y ++SG
Sbjct: 1233 GSLSTTDANASDTFTYALVSG 1253



 Score =  132 bits (319), Expect = 1e-28
 Identities = 204/830 (24%), Positives = 328/830 (39%), Gaps = 87/830 (10%)

Query: 12   NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71
            N+ D  D      +     +V E  + GT+V T    D D G      Y +   T DT N
Sbjct: 402  NIPDLPDAQAPTNISLSSTTVAENVAVGTSVGTFSTMDPDSGDTHT--YALVSGTGDTDN 459

Query: 72   PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131
                              F I G +  LLT    D      YT+ V+ TD      +R+ 
Sbjct: 460  SS----------------FTISGNT--LLTAEVFDSSVQDTYTIRVQTTDSTGRTLERVF 501

Query: 132  STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191
            +     + + D N      S    +++ +E  S +    +  +  TD++ G      Y+I
Sbjct: 502  T-----LTVTDQNVAPTGISLSDTSIAENEAASTS----VGDLSTTDSNTG--DTFTYSI 550

Query: 192  I---GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
            +   G  T   F+I   S  +   ++LD+E   SY +V+R  D G  S   T    IN+ 
Sbjct: 551  VSIDGSTTDTTFAISGNS--LVATESLDFETKSSYTVVVRTTDQGGLSFDQT--FTINVD 606

Query: 249  DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD-L 307
            D+N+ AP    +L  +SV+++   G  +      D D    A  T+T      TG+ D  
Sbjct: 607  DINE-APT-AIALSDDSVADDSVSGTVVGSFTTTDVD----ASDTFTYALVSGTGDTDNA 660

Query: 308  PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367
              TI      + T+  +D +TQ+ Y + +  TD G        T                
Sbjct: 661  SFTIVGNE--LRTATTIDFDTQSSYSIRIQTTDSGGETFEQVFTIVQSNEGPTAISLS-- 716

Query: 368  PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427
                +  +AE+   G  V T ++TD    +   Y    G      ++   +G  L T A 
Sbjct: 717  ----DSTVAENGSAGDTVGTFSSTDPTSGDTFTYTFVTGEGDDDNALFQIDGDELQT-AG 771

Query: 428  PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
             LD + +    + V +TDS G        I ++  N  AP       T  V    P GTT
Sbjct: 772  SLDAETQGTLTIRVRSTDSTGEFTEETFTITVSSVNE-APTTITLSGT-HVATGEPSGTT 829

Query: 488  VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
            V  +   D D G    ITY+L S   +      +  F I+   G + T    +++T S Y
Sbjct: 830  VGTLGTDDPDSG--DTITYTLVSGTGDT----DNASFTIS--NGELVTAFAANQQTQSSY 881

Query: 548  LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
             + V A+D    S  +T  + I+  +V              ++ E+A +GT+V  +  TD
Sbjct: 882  SVRVRAQDADGLSTEETFTITITSTNVAPTAIAIDNN----DVEENADIGTTVGTLSTTD 937

Query: 608  ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667
            A+   +          D +  SF ID  + V  T  +LD E+ +++ ++  + D   P  
Sbjct: 938  ANTMDSFVYTLVSGTGDTDNASFAIDGNNLV--TAASLDFETQSSYSVRIQSTD---PFG 992

Query: 668  SSTV-IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
             STV    I   ++ND+P     D  T  I+E++  GTT+G     D D        Y++
Sbjct: 993  LSTVETFTITATNVNDAPTAIAIDNST--IAEDTASGTTVGSFTTTDDDASDTFT--YAL 1048

Query: 727  KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVT 785
              GD     +  T  G++   LVT    D+E+ +  Y + ++   S     +  + I VT
Sbjct: 1049 VSGDGDTDNAAFTISGNN---LVTATTFDFET-QSSYSIRVQTTDSAGATFEQVLTITVT 1104

Query: 786  DVND-NAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSG 834
            D N+    +  D   I  +      VG F      DAD +D   Y ++SG
Sbjct: 1105 DTNEVPTAISLDNSSISEDAASGTTVGAFSTT---DADASDTFTYTLVSG 1151



 Score =  115 bits (276), Expect = 2e-23
 Identities = 151/620 (24%), Positives = 249/620 (40%), Gaps = 57/620 (9%)

Query: 227 IRAQDGGSP-SRSNTTQLLI-----NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQ 280
           +  QDG SP   S+  + ++     NI D+ D       SL   +V+ENV +G S+    
Sbjct: 377 VTGQDGLSPLDASDLLRRVVGLSTPNIPDLPDAQAPTNISLSSTTVAENVAVGTSVGTFS 436

Query: 281 AYDADEGVNAELTYTMTDKDYTGNVD-LPITIDPRSGWVYTSGQLDRETQAKYQLLVTAT 339
             D D G     T+T      TG+ D    TI   +  + T+   D   Q  Y + V  T
Sbjct: 437 TMDPDSGD----THTYALVSGTGDTDNSSFTISGNT--LLTAEVFDSSVQDTYTIRVQTT 490

Query: 340 DGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRL 399
           D          T                    +  +AE+E   T V  L+ TD++  +  
Sbjct: 491 DSTGRTLERVFTLTVTDQNVAPTGISLS----DTSIAENEAASTSVGDLSTTDSNTGDTF 546

Query: 400 HYEIT---GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ 456
            Y I    G  T   F+I+   G  L+   + LDF+ +  Y + V  TD GG S      
Sbjct: 547 TYSIVSIDGSTTDTTFAIS---GNSLVAT-ESLDFETKSSYTVVVRTTDQGGLSFDQTFT 602

Query: 457 INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA 516
           IN+ D N  AP    A    SV +D+  GT  +V S T +DV  +   TY+L   +S   
Sbjct: 603 INVDDINE-APT-AIALSDDSVADDSVSGT--VVGSFTTTDVDASDTFTYAL---VSGTG 655

Query: 517 VAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVND 576
              +    ++  +    TT   +D +T S Y + +   D G     +T +   ++V  N+
Sbjct: 656 DTDNASFTIVGNELRTATT---IDFDTQSSYSIRIQTTDSG----GETFEQVFTIVQSNE 708

Query: 577 NEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS 636
                   L  + + E+   G +V    +TD   G      +     D +   F ID   
Sbjct: 709 GPTAI--SLSDSTVAENGSAGDTVGTFSSTDPTSGDTFTYTFVTGEGDDDNALFQID--G 764

Query: 637 GVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696
             ++T  +LD E+  T  ++  + D        T    I +  +N++P          ++
Sbjct: 765 DELQTAGSLDAETQGTLTIRVRSTDSTGEFTEETFT--ITVSSVNEAPTTITLS--GTHV 820

Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756
           +   P GTT+G +   DPD G + + +  + G  D+++ S     G    ELVT    + 
Sbjct: 821 ATGEPSGTTVGTLGTDDPDSG-DTITYTLVSGTGDTDNASFTISNG----ELVTAFAANQ 875

Query: 757 ESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFG 814
           ++ +  Y + +RA  +  L  +    I +T  N  AP      I  N+ ++   +G   G
Sbjct: 876 QT-QSSYSVRVRAQDADGLSTEETFTITITSTN-VAPTA--IAIDNNDVEENADIGTTVG 931

Query: 815 RVPAYDADVTDKLQYRILSG 834
            +   DA+  D   Y ++SG
Sbjct: 932 TLSTTDANTMDSFVYTLVSG 951



 Score = 90.6 bits (215), Expect = 5e-16
 Identities = 136/553 (24%), Positives = 222/553 (40%), Gaps = 72/553 (13%)

Query: 11   INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
            I+V D N+      +    +SV E  +SGT V  L  TD D G      +T  LV+ D  
Sbjct: 1503 ISVTDVNETPTAIAIDN--SSVAEDVASGTVVGALSTTDADAGDT----FTYALVSGDG- 1555

Query: 71   NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            + ++A              F IDG +  L+T  + D E    Y+V V+ TD     SD  
Sbjct: 1556 DTDNAS-------------FTIDGSN--LVTATTFDFETQDSYSVRVQTTD-----SDGA 1595

Query: 131  SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            +   T+ ++I D N+     S  +  V+ D     T    +     TD D  A+    Y 
Sbjct: 1596 TFEQTLTISITDVNEAPTAISISSSVVTEDS----TSGTTVGSFSTTDVD--ASDTFTYT 1649

Query: 191  IIGGN---TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
            ++ G+       F+ID   G++    TLD +   SY + +R+ D G      T    I +
Sbjct: 1650 LVAGDGDTDNASFTIDG--GNLVTATTLDMDTQSSYSIRVRSTDAGGSFVEQT--FTITV 1705

Query: 248  RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
             + N +AP    +L   +++EN  IG  +  +   DAD  V    TY++      G+ D 
Sbjct: 1706 TETN-SAPTAI-ALDDATIAENAAIGTVVGALSTTDAD--VADTFTYSLVSG--VGDTDN 1759

Query: 308  PI-TIDPRSGWVYTSGQLDRETQAKYQLLVTATDG-GDPPRSATATXXXXXXXXXXXXXX 365
             +  ID   G + T+   D ETQ+ Y + + ++D  G+    +                 
Sbjct: 1760 ALFAID--GGNLVTAATFDFETQSSYSVRIQSSDAVGETVSQSFVITVVDINDAPTGLTL 1817

Query: 366  FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGN---TRGRFSITSQNGRGL 422
              P      +A  +  G  V  L A D D  +   +E   G       +F++      G 
Sbjct: 1818 PFPA-----IASGQASGFLVGNLGAEDQDAGDTFTFEFVSGEGDLDNDKFTLVD----GA 1868

Query: 423  ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
            +  A+  D   +  Y + V  TDS G +      + +T+  N AP       T +V + A
Sbjct: 1869 LRTAEATDDAIQALYSIRVRVTDSDGLTFEDTADLIVTE-ENVAPTAILLDAT-TVADGA 1926

Query: 483  PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
              GTTV   +ATD++        +     ++ E    +    +++   G +TTN   D  
Sbjct: 1927 ASGTTVGTFTATDANDFDEHTFEF-----VAGEGDTDNASFTIVD---GVLTTNFEADAS 1978

Query: 543  TMSGYLLTVTARD 555
            T S Y + V + D
Sbjct: 1979 TQSSYSIRVLSTD 1991


>UniRef50_Q4RIZ0 Cluster: Chromosome undetermined SCAF15040, whole
           genome shotgun sequence; n=3; Tetraodontidae|Rep:
           Chromosome undetermined SCAF15040, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 839

 Score =  167 bits (407), Expect = 3e-39
 Identities = 146/547 (26%), Positives = 247/547 (45%), Gaps = 49/547 (8%)

Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYE 218
           + E+ + +D   I K+++ D D G N  ++Y + G      F ID  +GD+   + LD E
Sbjct: 31  LQEEYTGSDYQYIGKLQS-DQDHG-NGLVKYVLSGEGAGNIFIIDENNGDLHATRRLDRE 88

Query: 219 QVRSYRL---VIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275
           +   Y L   V+  + G        T+  I + D+NDN P F   ++  SV E   IG S
Sbjct: 89  EKAYYILKATVVNKRTG--QKLEPETEFTIKLHDINDNEPHFSQEVYTGSVPERSDIGTS 146

Query: 276 IVRVQAYDADEGV---NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS---GQLDRETQ 329
           +++V A DAD+G+   +A+L Y+++     G+     ++DP +G + T+   G +DRE +
Sbjct: 147 VIQVTATDADDGMYGNSAKLVYSISQ----GHP--YFSVDPNTGVIRTALGPGDMDREQR 200

Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX--XFMPGQYEVELAEDEPPGTPVVT 387
             YQ+++ A D        T T                F    Y+  + E    GTPV  
Sbjct: 201 EHYQVVIEAKDMAGQRGGLTGTTVVNITLTDVNDNPPRFTQSIYQFRVPESSESGTPVGR 260

Query: 388 LTATDAD--EDNRLHYEITGGNTRGRFSITSQNG--RGLITVAQPLDFKQERRYVLTVSA 443
           + A D D  E+  +++ I  G+    F I +      G+ITV++PLD++++  Y + +  
Sbjct: 261 IRAADKDIGENAEMYFTIVSGDGLDTFDIFTDKATQEGVITVSKPLDYEKKPSYTVEIQV 320

Query: 444 TD--------SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495
            +        S G  D A V+I + D +   P+F+ A Y   V EDA +G  +  VSA D
Sbjct: 321 QNTQIDPRFMSPGSKDVATVRIAVEDVDE-PPLFDKASYLMEVKEDAAVGVALGSVSAID 379

Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555
            D G    + Y++            D  F ++P  G++   K LDRE  + + ++V A +
Sbjct: 380 PD-GARNIVKYAIDRR------TDMDHLFNVHPGNGSVFLLKSLDREESAWHNISVIATE 432

Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG- 614
                 S    V I ++DVNDN P     +Y   +         +  V A D D    G 
Sbjct: 433 LHNSRQSSHVPVFIHLLDVNDNAPTL-ATVYETFVSRPN--QNRIQTVRAVDVDEPSAGH 489

Query: 615 RIHYELDPKDREEGSFVI----DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST 670
           + ++ L P+     +F I    D  + ++    +  R   + + +  V  DG  P QSST
Sbjct: 490 KFYFSLAPEGTYRSNFTIRDNGDNTASILTRRASYSRLQQSMYLVPVVITDGDYPMQSST 549

Query: 671 VIVHIKI 677
             + +++
Sbjct: 550 GTLTVRV 556



 Score =  152 bits (369), Expect = 1e-34
 Identities = 136/486 (27%), Positives = 217/486 (44%), Gaps = 33/486 (6%)

Query: 283 DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG 342
           D D G N  + Y ++ +   GN+ +   ID  +G ++ + +LDRE +A Y L  T  +  
Sbjct: 49  DQDHG-NGLVKYVLSGEG-AGNIFI---IDENNGDLHATRRLDREEKAYYILKATVVNKR 103

Query: 343 DPPRSATATXXXXXXXXXXXXX-XFMPGQYEVELAEDEPPGTPVVTLTATDADE-----D 396
              +    T               F    Y   + E    GT V+ +TATDAD+      
Sbjct: 104 TGQKLEPETEFTIKLHDINDNEPHFSQEVYTGSVPERSDIGTSVIQVTATDADDGMYGNS 163

Query: 397 NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR--YVLTVSATDS----GGRS 450
            +L Y I+ G+    FS+    G  + T   P D  +E+R  Y + + A D     GG +
Sbjct: 164 AKLVYSISQGHPY--FSVDPNTGV-IRTALGPGDMDREQREHYQVVIEAKDMAGQRGGLT 220

Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510
            T +V I +TD N+  P F  + Y   V E +  GT V  + A D D+G NA++ +++  
Sbjct: 221 GTTVVNITLTDVNDNPPRFTQSIYQFRVPESSESGTPVGRIRAADKDIGENAEMYFTI-- 278

Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV------PSLSDT 564
            +S + +   D       Q G IT +K LD E    Y + +  ++  +      P   D 
Sbjct: 279 -VSGDGLDTFDIFTDKATQEGVITVSKPLDYEKKPSYTVEIQVQNTQIDPRFMSPGSKDV 337

Query: 565 TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624
             V I+V DV D  P+F +  Y   + EDA VG ++  V A D D G    + Y +D + 
Sbjct: 338 ATVRIAVEDV-DEPPLFDKASYLMEVKEDAAVGVALGSVSAIDPD-GARNIVKYAIDRRT 395

Query: 625 REEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP 684
             +  F + P +G +   K+LDRE  A H++  +A +     QSS V V I + D+ND+ 
Sbjct: 396 DMDHLFNVHPGNGSVFLLKSLDREESAWHNISVIATELHNSRQSSHVPVFIHLLDVNDNA 455

Query: 685 PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD 744
           P   +   TF    N     T+  +   +P  G       + +G   SN F++    G +
Sbjct: 456 PTLATVYETFVSRPNQNRIQTVRAVDVDEPSAGHKFYFSLAPEGTYRSN-FTIRD-NGDN 513

Query: 745 KAELVT 750
            A ++T
Sbjct: 514 TASILT 519



 Score =  146 bits (353), Expect = 1e-32
 Identities = 123/424 (29%), Positives = 197/424 (46%), Gaps = 33/424 (7%)

Query: 391 TDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL--TVSATDSGG 448
           +D D  N L   +  G   G   I  +N  G +   + LD +++  Y+L  TV    +G 
Sbjct: 48  SDQDHGNGLVKYVLSGEGAGNIFIIDENN-GDLHATRRLDREEKAYYILKATVVNKRTGQ 106

Query: 449 RSDTAM-VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI---NAQI 504
           + +      I + D N+  P F    YT SV E + IGT+V+ V+ATD+D G+   +A++
Sbjct: 107 KLEPETEFTIKLHDINDNEPHFSQEVYTGSVPERSDIGTSVIQVTATDADDGMYGNSAKL 166

Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL---LDRETMSGYLLTVTARD--GGVP 559
            YS+S         H    F ++P TG I T      +DRE    Y + + A+D  G   
Sbjct: 167 VYSISQ-------GH--PYFSVDPNTGVIRTALGPGDMDREQREHYQVVIEAKDMAGQRG 217

Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619
            L+ TT V I++ DVNDN P F Q +Y   + E +  GT V ++ A D D+G N  +++ 
Sbjct: 218 GLTGTTVVNITLTDVNDNPPRFTQSIYQFRVPESSESGTPVGRIRAADKDIGENAEMYFT 277

Query: 620 LDPKDR-EEGSFVIDPAS--GVIRTNKALDRESVATHDLKA----VAIDGG--TPPQSST 670
           +   D  +      D A+  GVI  +K LD E   ++ ++       ID    +P     
Sbjct: 278 IVSGDGLDTFDIFTDKATQEGVITVSKPLDYEKKPSYTVEIQVQNTQIDPRFMSPGSKDV 337

Query: 671 VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD 730
             V I +ED+ D PP+F+       + E++ +G  +G + A DPD G   +V Y+I    
Sbjct: 338 ATVRIAVEDV-DEPPLFDKASYLMEVKEDAAVGVALGSVSAIDPD-GARNIVKYAIDRRT 395

Query: 731 DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDN 790
           D +        G+    L+  +D +  +      +     +    + V V I + DVNDN
Sbjct: 396 DMDHL-FNVHPGNGSVFLLKSLDREESAWHNISVIATELHNSRQSSHVPVFIHLLDVNDN 454

Query: 791 APVM 794
           AP +
Sbjct: 455 APTL 458



 Score =  144 bits (350), Expect = 2e-32
 Identities = 109/343 (31%), Positives = 162/343 (47%), Gaps = 23/343 (6%)

Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553
           +D D G N  + Y LS E +          F+I+   G +   + LDRE  + Y+L  T 
Sbjct: 48  SDQDHG-NGLVKYVLSGEGAGNI-------FIIDENNGDLHATRRLDREEKAYYILKATV 99

Query: 554 RDGGV-PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612
            +      L   T+  I + D+NDNEP F Q++YT ++ E + +GTSV QV ATDAD G+
Sbjct: 100 VNKRTGQKLEPETEFTIKLHDINDNEPHFSQEVYTGSVPERSDIGTSVIQVTATDADDGM 159

Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKA---LDRESVATHDLKAVAID--GGTPPQ 667
            G     +    +    F +DP +GVIRT      +DRE    + +   A D  G     
Sbjct: 160 YGNSAKLVYSISQGHPYFSVDPNTGVIRTALGPGDMDREQREHYQVVIEAKDMAGQRGGL 219

Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727
           + T +V+I + D+ND+PP F      F + E+S  GT +G IRA D D G NA ++++I 
Sbjct: 220 TGTTVVNITLTDVNDNPPRFTQSIYQFRVPESSESGTPVGRIRAADKDIGENAEMYFTIV 279

Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPRKKYELVI-------RAASPPLWNDVR 779
            GD  ++F + T + + +  +     LDYE  P    E+ +       R  SP   +   
Sbjct: 280 SGDGLDTFDIFTDKATQEGVITVSKPLDYEKKPSYTVEIQVQNTQIDPRFMSPGSKDVAT 339

Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD 822
           V I V DV D  P+      +    +D       G V A D D
Sbjct: 340 VRIAVEDV-DEPPLFDKASYLMEVKEDAAVGVALGSVSAIDPD 381



 Score =  137 bits (332), Expect = 4e-30
 Identities = 139/504 (27%), Positives = 215/504 (42%), Gaps = 35/504 (6%)

Query: 88  DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
           ++F ID  +G L     LDRE+ A Y  ++KAT        +L       + + D NDN 
Sbjct: 68  NIFIIDENNGDLHATRRLDREEKAYY--ILKATVVNKRTGQKLEPETEFTIKLHDINDNE 125

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG--ANSA-IRYAIIGGNTQMQFSIDS 204
           P FS++ YT SV E   +  +  + ++ ATDAD G   NSA + Y+I  G+    FS+D 
Sbjct: 126 PHFSQEVYTGSVPERSDIGTS--VIQVTATDADDGMYGNSAKLVYSISQGHPY--FSVDP 181

Query: 205 LSGDVSLVK---TLDYEQVRSYRLVIRAQD--GGSPSRSNTTQLLINIRDVNDNAPRFYT 259
            +G +        +D EQ   Y++VI A+D  G     + TT + I + DVNDN PRF  
Sbjct: 182 NTGVIRTALGPGDMDREQREHYQVVIEAKDMAGQRGGLTGTTVVNITLTDVNDNPPRFTQ 241

Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319
           S++Q  V E+   G  + R++A D D G NAE+ +T+   D     D+      + G + 
Sbjct: 242 SIYQFRVPESSESGTPVGRIRAADKDIGENAEMYFTIVSGDGLDTFDIFTDKATQEGVIT 301

Query: 320 TSGQLDRETQAKYQLLVTATDGG-DP----PRSATATXXXXXXXXXXXXXXFMPGQYEVE 374
            S  LD E +  Y + +   +   DP    P S                  F    Y +E
Sbjct: 302 VSKPLDYEKKPSYTVEIQVQNTQIDPRFMSPGSKDVATVRIAVEDVDEPPLFDKASYLME 361

Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434
           + ED   G  + +++A D D    +        T          G G + + + LD ++ 
Sbjct: 362 VKEDAAVGVALGSVSAIDPDGARNIVKYAIDRRTDMDHLFNVHPGNGSVFLLKSLDREES 421

Query: 435 RRYVLTVSATD--SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492
             + ++V AT+  +  +S    V I++ D N+ AP       T   F   P    +  V 
Sbjct: 422 AWHNISVIATELHNSRQSSHVPVFIHLLDVNDNAPTLATVYET---FVSRPNQNRIQTVR 478

Query: 493 ATDSD-VGINAQITYSLSSEISNEAVAHHDQQFVI---NPQTGAITTNKL-LDRETMSGY 547
           A D D      +  +SL+ E        +   F I      T +I T +    R   S Y
Sbjct: 479 AVDVDEPSAGHKFYFSLAPE------GTYRSNFTIRDNGDNTASILTRRASYSRLQQSMY 532

Query: 548 LLTVTARDGGVPSLSDTTDVEISV 571
           L+ V   DG  P  S T  + + V
Sbjct: 533 LVPVVITDGDYPMQSSTGTLTVRV 556



 Score =  116 bits (279), Expect = 9e-24
 Identities = 117/457 (25%), Positives = 199/457 (43%), Gaps = 54/457 (11%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVTA 67
           I + D ND+ P F  + Y  SV E +  GT+V+ + ATD D    G +A++ Y+I     
Sbjct: 116 IKLHDINDNEPHFSQEVYTGSVPERSDIGTSVIQVTATDADDGMYGNSAKLVYSI----- 170

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR---ASLDREKVARYTVLVKATDQAS 124
                                 F +D  +G + T      +DRE+   Y V+++A D A 
Sbjct: 171 ----------------SQGHPYFSVDPNTGVIRTALGPGDMDREQREHYQVVIEAKDMAG 214

Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184
                L+ T  +++ + D NDN P+F++  Y   V E  S +  PV  +I+A D D+G N
Sbjct: 215 Q-RGGLTGTTVVNITLTDVNDNPPRFTQSIYQFRVPES-SESGTPV-GRIRAADKDIGEN 271

Query: 185 SAIRYAIIGGNTQMQFSI----DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG------S 234
           + + + I+ G+    F I     +  G +++ K LDYE+  SY + I+ Q+        S
Sbjct: 272 AEMYFTIVSGDGLDTFDIFTDKATQEGVITVSKPLDYEKKPSYTVEIQVQNTQIDPRFMS 331

Query: 235 PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294
           P   +   + I + DV D  P F  + +   V E+  +G ++  V A D D G    + Y
Sbjct: 332 PGSKDVATVRIAVEDV-DEPPLFDKASYLMEVKEDAAVGVALGSVSAIDPD-GARNIVKY 389

Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354
            +   D   ++D    + P +G V+    LDRE  A + + V AT+  +  R ++     
Sbjct: 390 AI---DRRTDMDHLFNVHPGNGSVFLLKSLDREESAWHNISVIATELHN-SRQSSHVPVF 445

Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE---DNRLHYEIT-GGNTRG 410
                       +   YE  ++   P    + T+ A D DE    ++ ++ +   G  R 
Sbjct: 446 IHLLDVNDNAPTLATVYETFVS--RPNQNRIQTVRAVDVDEPSAGHKFYFSLAPEGTYRS 503

Query: 411 RFSI--TSQNGRGLITVAQPLDFKQERRYVLTVSATD 445
            F+I     N   ++T        Q+  Y++ V  TD
Sbjct: 504 NFTIRDNGDNTASILTRRASYSRLQQSMYLVPVVITD 540



 Score =  115 bits (277), Expect = 2e-23
 Identities = 102/348 (29%), Positives = 161/348 (46%), Gaps = 30/348 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I + D ND+ P F    Y+  V E + SGT V  ++A D+DIG+NAE+ +TI  V+ D L
Sbjct: 227 ITLTDVNDNPPRFTQSIYQFRVPESSESGTPVGRIRAADKDIGENAEMYFTI--VSGDGL 284

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD-QASP--VS 127
           +  D                    + G +     LD EK   YTV ++  + Q  P  +S
Sbjct: 285 DTFDIFTDKAT-------------QEGVITVSKPLDYEKKPSYTVEIQVQNTQIDPRFMS 331

Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
                 AT+ +  ++D D  P F + +Y + V ED +V     +  + A D D GA + +
Sbjct: 332 PGSKDVATVRI-AVEDVDEPPLFDKASYLMEVKEDAAV--GVALGSVSAIDPD-GARNIV 387

Query: 188 RYAIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
           +YA I   T M   F++   +G V L+K+LD E+   + + + A +  +  +S+   + I
Sbjct: 388 KYA-IDRRTDMDHLFNVHPGNGSVFLLKSLDREESAWHNISVIATELHNSRQSSHVPVFI 446

Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY--TMTDKDYTG 303
           ++ DVNDNAP   T +++  VS   P    I  V+A D DE       Y     +  Y  
Sbjct: 447 HLLDVNDNAPTLAT-VYETFVSR--PNQNRIQTVRAVDVDEPSAGHKFYFSLAPEGTYRS 503

Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
           N  +    D  +  +       R  Q+ Y + V  TDG  P +S+T T
Sbjct: 504 NFTIRDNGDNTASILTRRASYSRLQQSMYLVPVVITDGDYPMQSSTGT 551


>UniRef50_Q95YK9 Cluster: Type II cadherin; n=1; Ciona savignyi|Rep:
           Type II cadherin - Ciona savignyi (Pacific transparent
           sea squirt)
          Length = 910

 Score =  167 bits (407), Expect = 3e-39
 Identities = 144/479 (30%), Positives = 213/479 (44%), Gaps = 36/479 (7%)

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
           I+P SG ++   +LDRE Q+ Y+L V+A DG   P    +               F PG 
Sbjct: 185 IEPLSGHLFLKQKLDREMQSSYKLNVSAHDGNGVPLEPASEITIDVLDENDNPPEFAPGP 244

Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEI------TGGNTRGRFSITSQNGRGLIT 424
           +   + E  P GT V  + A DAD+  + + +I      + G+   +F I  + G  + T
Sbjct: 245 HHARVKERSPSGTKVADVIARDADDPQQPYGQIRYSLLPSPGDATNKFMIHHERGT-VST 303

Query: 425 VAQPLDFKQERRYVLTVSATDSGGR----SDTAMVQINITDANNYAPVFENAPYTASVFE 480
           +   LD ++   Y L + A D        S T  + I++ D N+  PVF N PY   V E
Sbjct: 304 ITSNLDREESATYELVIQARDDPNARLSFSATTTLTISVIDVNDSPPVFVNEPYKPIVAE 363

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           DA IG+ ++ +S TD+DVG NAQ  Y +      +  A    + + N   G +   K LD
Sbjct: 364 DAKIGSEIVRLSTTDADVGENAQSIYVIED---GDDSAMFSIEAIDN--LGVLKVKKRLD 418

Query: 541 RETMSG--YLLTVTARD-------GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
            ET     Y + V AR+         + S+ D TDV I+V DVN+  P F +  Y  ++ 
Sbjct: 419 YETAPDHKYSVRVRARNTHPDPNLAYLGSMDDVTDVVITVTDVNE-PPEFTEVNYEFSVR 477

Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA 651
           EDA+ G  +  V A D +        Y L  +D E   F ID  SG+I     LDRE  A
Sbjct: 478 EDAIRGFPIRAVTAVDPE---GDSFSYFL--RD-ESKRFAIDAVSGMISVAGELDRELQA 531

Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP-VFESDCLTFYISENSPIGTTI--GE 708
           T+D+   A   G     ST  V I I D+ND+PP   + D +   + +N      I   +
Sbjct: 532 TYDVTVYAGSPGDLDFRSTARVTISISDVNDNPPHPLDGDTVQVVLCDNQHEKGQILHPK 591

Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
           I+  DPD   N    ++    +  N    E     D    +      Y S  ++YEL +
Sbjct: 592 IKFTDPDSPING-QPFTYYSTEHDNYKHFELVNNDDGTASLRTAHRGYSSSIREYELPV 649



 Score =  149 bits (362), Expect = 8e-34
 Identities = 145/536 (27%), Positives = 234/536 (43%), Gaps = 45/536 (8%)

Query: 167 DNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLV 226
           ++ +IA+++++  +      + Y+I G      F I+ LSG + L + LD E   SY+L 
Sbjct: 152 EDQLIARLRSSYDNY--TGTVIYSISGRGADSLFQIEPLSGHLFLKQKLDREMQSSYKLN 209

Query: 227 IRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE 286
           + A DG        +++ I++ D NDN P F        V E  P G  +  V A DAD+
Sbjct: 210 VSAHDGNGVPLEPASEITIDVLDENDNPPEFAPGPHHARVKERSPSGTKVADVIARDADD 269

Query: 287 GVN--AELTYTMTDKDYTGNVDLPITIDPRSGWVYT-SGQLDRETQAKYQLLVTATDGGD 343
                 ++ Y++      G+      I    G V T +  LDRE  A Y+L++ A D  +
Sbjct: 270 PQQPYGQIRYSLLPSP--GDATNKFMIHHERGTVSTITSNLDREESATYELVIQARDDPN 327

Query: 344 PPRS--ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRL 399
              S  AT T              F+   Y+  +AED   G+ +V L+ TDAD  E+ + 
Sbjct: 328 ARLSFSATTTLTISVIDVNDSPPVFVNEPYKPIVAEDAKIGSEIVRLSTTDADVGENAQS 387

Query: 400 HYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ--ERRYVLTVSATDS---------GG 448
            Y I  G+    FSI + +  G++ V + LD++   + +Y + V A ++         G 
Sbjct: 388 IYVIEDGDDSAMFSIEAIDNLGVLKVKKRLDYETAPDHKYSVRVRARNTHPDPNLAYLGS 447

Query: 449 RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508
             D   V I +TD N   P F    Y  SV EDA  G  +  V+A D +       +Y L
Sbjct: 448 MDDVTDVVITVTDVNE-PPEFTEVNYEFSVREDAIRGFPIRAVTAVDPE---GDSFSYFL 503

Query: 509 SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568
             E          ++F I+  +G I+    LDRE  + Y +TV A   G      T  V 
Sbjct: 504 RDE---------SKRFAIDAVSGMISVAGELDRELQATYDVTVYAGSPGDLDFRSTARVT 554

Query: 569 ISVVDVNDNEPV-----FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR--IHYELD 621
           IS+ DVNDN P        Q +   N  E   +     ++  TD D  +NG+   +Y  +
Sbjct: 555 ISISDVNDNPPHPLDGDTVQVVLCDNQHEKGQI--LHPKIKFTDPDSPINGQPFTYYSTE 612

Query: 622 PKDREEGSFVI-DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676
             + +    V  D  +  +RT       S+  ++L  +  D G+P  ++T  + ++
Sbjct: 613 HDNYKHFELVNNDDGTASLRTAHRGYSSSIREYELPVIVEDNGSPKLNATYTITVR 668



 Score =  144 bits (349), Expect = 3e-32
 Identities = 130/415 (31%), Positives = 195/415 (46%), Gaps = 44/415 (10%)

Query: 401 YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQIN 458
           Y I+G      F I   +G   + + Q LD + +  Y L VSA D  G      + + I+
Sbjct: 172 YSISGRGADSLFQIEPLSGH--LFLKQKLDREMQSSYKLNVSAHDGNGVPLEPASEITID 229

Query: 459 ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN--AQITYSL---SSEIS 513
           + D N+  P F   P+ A V E +P GT V  V A D+D       QI YSL     + +
Sbjct: 230 VLDENDNPPEFAPGPHHARVKERSPSGTKVADVIARDADDPQQPYGQIRYSLLPSPGDAT 289

Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD--GGVPSLSDTTDVEISV 571
           N+ + HH++  V       IT+N  LDRE  + Y L + ARD      S S TT + ISV
Sbjct: 290 NKFMIHHERGTV-----STITSN--LDREESATYELVIQARDDPNARLSFSATTTLTISV 342

Query: 572 VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631
           +DVND+ PVF  + Y   + EDA +G+ + ++  TDADVG N +  Y ++  D +   F 
Sbjct: 343 IDVNDSPPVFVNEPYKPIVAEDAKIGSEIVRLSTTDADVGENAQSIYVIEDGD-DSAMFS 401

Query: 632 IDPAS--GVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI---------VHIKIEDI 680
           I+     GV++  K LD E+   H          T P  +            V I + D+
Sbjct: 402 IEAIDNLGVLKVKKRLDYETAPDHKYSVRVRARNTHPDPNLAYLGSMDDVTDVVITVTDV 461

Query: 681 NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR 740
           N+ PP F      F + E++  G  I  + A DP EG +    Y ++  D+S  F+++  
Sbjct: 462 NE-PPEFTEVNYEFSVREDAIRGFPIRAVTAVDP-EGDS--FSYFLR--DESKRFAIDAV 515

Query: 741 QGSDKAELVTMVDLDYESPRKKYELVIRAASP---PLWNDVRVEILVTDVNDNAP 792
            G     +    +LD E  +  Y++ + A SP      +  RV I ++DVNDN P
Sbjct: 516 SGM----ISVAGELDREL-QATYDVTVYAGSPGDLDFRSTARVTISISDVNDNPP 565



 Score =  137 bits (331), Expect = 5e-30
 Identities = 122/370 (32%), Positives = 180/370 (48%), Gaps = 27/370 (7%)

Query: 521 DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEP 579
           D  F I P +G +   + LDRE  S Y L V+A DG GVP L   +++ I V+D NDN P
Sbjct: 180 DSLFQIEPLSGHLFLKQKLDREMQSSYKLNVSAHDGNGVP-LEPASEITIDVLDENDNPP 238

Query: 580 VFKQQLYTANIMEDALVGTSVSQVGATDADVGLN--GRIHYELDPKDRE-EGSFVIDPAS 636
            F    + A + E +  GT V+ V A DAD      G+I Y L P   +    F+I    
Sbjct: 239 EFAPGPHHARVKERSPSGTKVADVIARDADDPQQPYGQIRYSLLPSPGDATNKFMIHHER 298

Query: 637 GVIRT-NKALDRESVATHDLKAVAID--GGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693
           G + T    LDRE  AT++L   A D        S+T  + I + D+NDSPPVF ++   
Sbjct: 299 GTVSTITSNLDREESATYELVIQARDDPNARLSFSATTTLTISVIDVNDSPPVFVNEPYK 358

Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753
             ++E++ IG+ I  +   D D G NA   Y I+ GDDS  FS+E     +   L     
Sbjct: 359 PIVAEDAKIGSEIVRLSTTDADVGENAQSIYVIEDGDDSAMFSIEAI--DNLGVLKVKKR 416

Query: 754 LDYE-SPRKKYELVIRAAS----PPL-----WNDVR-VEILVTDVNDNAPVMKDFQIIFN 802
           LDYE +P  KY + +RA +    P L      +DV  V I VTDVN+  P   +    F+
Sbjct: 417 LDYETAPDHKYSVRVRARNTHPDPNLAYLGSMDDVTDVVITVTDVNE-PPEFTEVNYEFS 475

Query: 803 NYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKL 862
             +D     P   V A D +  D   Y +   + +    ++  +G ++++ +L+  +   
Sbjct: 476 VREDAIRGFPIRAVTAVDPE-GDSFSYFL--RDESKRFAIDAVSGMISVAGELDRELQ-- 530

Query: 863 ATMEVSVTDG 872
           AT +V+V  G
Sbjct: 531 ATYDVTVYAG 540



 Score =  134 bits (323), Expect = 4e-29
 Identities = 144/501 (28%), Positives = 222/501 (44%), Gaps = 35/501 (6%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           +F+I+  SG L  +  LDRE  + Y + V A D  + V   L   + I ++++D+NDN P
Sbjct: 182 LFQIEPLSGHLFLKQKLDREMQSSYKLNVSAHD-GNGVP--LEPASEITIDVLDENDNPP 238

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN--SAIRYAII--GGNTQMQFSIDS 204
           +F+   +   V E         +A + A DAD        IRY+++   G+   +F I  
Sbjct: 239 EFAPGPHHARVKE--RSPSGTKVADVIARDADDPQQPYGQIRYSLLPSPGDATNKFMIHH 296

Query: 205 LSGDVS-LVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQLLINIRDVNDNAPRFYTSL 261
             G VS +   LD E+  +Y LVI+A+D  +   S S TT L I++ DVND+ P F    
Sbjct: 297 ERGTVSTITSNLDREESATYELVIQARDDPNARLSFSATTTLTISVIDVNDSPPVFVNEP 356

Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321
           ++  V+E+  IG  IVR+   DAD G NA+  Y + D D +    +   ID   G +   
Sbjct: 357 YKPIVAEDAKIGSEIVRLSTTDADVGENAQSIYVIEDGDDSAMFSIE-AID-NLGVLKVK 414

Query: 322 GQLDRET--QAKYQLLVTATDGGDPPRSA------TATXXXXXXXXXXXXXXFMPGQYEV 373
            +LD ET    KY + V A +    P  A        T              F    YE 
Sbjct: 415 KRLDYETAPDHKYSVRVRARNTHPDPNLAYLGSMDDVTDVVITVTDVNEPPEFTEVNYEF 474

Query: 374 ELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ 433
            + ED   G P+  +TA D + D+  ++     +   RF+I + +  G+I+VA  LD + 
Sbjct: 475 SVREDAIRGFPIRAVTAVDPEGDSFSYFL---RDESKRFAIDAVS--GMISVAGELDREL 529

Query: 434 ERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV- 490
           +  Y +TV A   G      TA V I+I+D N+  P   +      V  D       ++ 
Sbjct: 530 QATYDVTVYAGSPGDLDFRSTARVTISISDVNDNPPHPLDGDTVQVVLCDNQHEKGQILH 589

Query: 491 --VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
             +  TD D  IN Q     S+E  N     H +    +  T ++ T       ++  Y 
Sbjct: 590 PKIKFTDPDSPINGQPFTYYSTEHDN---YKHFELVNNDDGTASLRTAHRGYSSSIREYE 646

Query: 549 LTVTARDGGVPSLSDTTDVEI 569
           L V   D G P L+ T  + +
Sbjct: 647 LPVIVEDNGSPKLNATYTITV 667



 Score = 93.1 bits (221), Expect = 1e-16
 Identities = 95/350 (27%), Positives = 158/350 (45%), Gaps = 34/350 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I+V+D ND  PVF  + Y+  V E A  G+ ++ L  TD D+G+NA+  Y I        
Sbjct: 340 ISVIDVNDSPPVFVNEPYKPIVAEDAKIGSEIVRLSTTDADVGENAQSIYVI-------- 391

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA--RYTVLVKATD-QASPVS 127
             ED           + ++       G L  +  LD E     +Y+V V+A +    P  
Sbjct: 392 --EDGDDSAMFSIEAIDNL-------GVLKVKKRLDYETAPDHKYSVRVRARNTHPDPNL 442

Query: 128 DRLSS--TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
             L S    T  V  + D +  P+F+E  Y  SV ED ++   P+ A + A D +     
Sbjct: 443 AYLGSMDDVTDVVITVTDVNEPPEFTEVNYEFSVRED-AIRGFPIRA-VTAVDPE---GD 497

Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245
           +  Y +   +   +F+ID++SG +S+   LD E   +Y + + A   G     +T ++ I
Sbjct: 498 SFSYFL--RDESKRFAIDAVSGMISVAGELDRELQATYDVTVYAGSPGDLDFRSTARVTI 555

Query: 246 NIRDVNDNAPR-FYTSLFQESVSENVPIGYSIV--RVQAYDADEGVNAE-LTYTMTDKDY 301
           +I DVNDN P        Q  + +N      I+  +++  D D  +N +  TY  T+ D 
Sbjct: 556 SISDVNDNPPHPLDGDTVQVVLCDNQHEKGQILHPKIKFTDPDSPINGQPFTYYSTEHDN 615

Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
             + +L +  D  +  + T+ +    +  +Y+L V   D G P  +AT T
Sbjct: 616 YKHFEL-VNNDDGTASLRTAHRGYSSSIREYELPVIVEDNGSPKLNATYT 664


>UniRef50_Q5NUI3 Cluster: Cadherin19; n=12; Mammalia|Rep: Cadherin19
           - Rattus norvegicus (Rat)
          Length = 770

 Score =  167 bits (406), Expect = 4e-39
 Identities = 144/507 (28%), Positives = 235/507 (46%), Gaps = 39/507 (7%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F ID ++G +     LDREK + Y +  +  D  + +   +   +   + + D NDN P+
Sbjct: 88  FSIDEKTGDIFAMQKLDREKQSLYILRAQVID--TTIGKAVEPESEFVIRVSDVNDNEPR 145

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDAD---VGANSAIRYAIIGGNTQMQFSIDSLS 206
           F ++ Y   V E     +   + K+ A DAD    G ++ I Y +  G  Q  FS++  +
Sbjct: 146 FLDEPYEAIVPE--MSPEGTFVIKVTANDADDPTSGYHARILYNLEQG--QPYFSVEPTT 201

Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDG-GSPSR-SNTTQLLINIRDVNDNAPRFYTSLFQE 264
           G + +   +D E   +Y ++I+A+D  G P   S TT + I + D+NDN P F  S ++ 
Sbjct: 202 GVIRISSKMDRELQDTYCVIIQAKDMLGQPGALSGTTTISIKLSDINDNKPIFKESFYRF 261

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
           ++SE+ P G +I ++ AYD D G NAE+ Y++ D D +   D+ I  + + G V    ++
Sbjct: 262 TISESAPSGTTIGKIMAYDDDIGENAEMDYSIED-DESQIFDIVIDNETQEGIVILKKKV 320

Query: 325 DRETQAKYQLLVTA----TDGGDPPR--SATATXXXXXXXXXXXXXXFMPGQYEVELAED 378
           D E Q  Y + V       D    P   +A+ T              F+   Y  E+ E 
Sbjct: 321 DFEHQNHYGIRVKVKNCHVDEELAPAHVNASTTYIKVQVEDEDEPPTFLLPYYIFEIPEG 380

Query: 379 EPPGTPVVTLTATDAD-EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437
           +P GT V T++A D D   + + Y + G      F I   NG G I     LD +    Y
Sbjct: 381 KPYGTMVGTVSAVDPDRRQSPMRYSLIGSK---MFDI---NGNGTIVTTNLLDREVSAWY 434

Query: 438 VLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495
            L+V+AT++    +  +A V + + + N++AP F    Y   V E+A  G  +  +SA D
Sbjct: 435 NLSVTATETYNVQQISSAHVYVQVLNINDHAPEFSQL-YETYVCENAESGEIIQTISAID 493

Query: 496 SDVGINAQITYSLSS--EISNEAVAHHDQQFVINPQTGAITTNKL---LDRETMSGYLLT 550
            D  I     Y   S  + +N +    D Q      T  I +N+    L  ET+  + + 
Sbjct: 494 RDESIEDHHFYFNHSVEDTNNSSFILTDNQ----DNTAVILSNRAGFSLKEETV--FYMI 547

Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDN 577
           +   D G+P L+ T  + I V D  D+
Sbjct: 548 ILIADNGIPPLTSTNTLTIQVCDCGDS 574



 Score =  150 bits (364), Expect = 5e-34
 Identities = 140/530 (26%), Positives = 233/530 (43%), Gaps = 45/530 (8%)

Query: 177 TDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG-SP 235
           +D D G NS  +Y ++G      FSID  +GD+  ++ LD E+   Y L  +  D     
Sbjct: 67  SDLDNGNNS-FQYKLLGTGDG-SFSIDEKTGDIFAMQKLDREKQSLYILRAQVIDTTIGK 124

Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE---GVNAEL 292
           +    ++ +I + DVNDN PRF    ++  V E  P G  +++V A DAD+   G +A +
Sbjct: 125 AVEPESEFVIRVSDVNDNEPRFLDEPYEAIVPEMSPEGTFVIKVTANDADDPTSGYHARI 184

Query: 293 TYTMTD-KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG-GDPPR-SAT 349
            Y +   + Y        +++P +G +  S ++DRE Q  Y +++ A D  G P   S T
Sbjct: 185 LYNLEQGQPY-------FSVEPTTGVIRISSKMDRELQDTYCVIIQAKDMLGQPGALSGT 237

Query: 350 ATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGN 407
            T              F    Y   ++E  P GT +  + A D D  E+  + Y I    
Sbjct: 238 TTISIKLSDINDNKPIFKESFYRFTISESAPSGTTIGKIMAYDDDIGENAEMDYSIEDDE 297

Query: 408 TR-GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT------ 460
           ++     I ++   G++ + + +DF+ +  Y + V   +     + A   +N +      
Sbjct: 298 SQIFDIVIDNETQEGIVILKKKVDFEHQNHYGIRVKVKNCHVDEELAPAHVNASTTYIKV 357

Query: 461 --DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518
             +  +  P F    Y   + E  P GT V  VSA D D    + + YSL          
Sbjct: 358 QVEDEDEPPTFLLPYYIFEIPEGKPYGTMVGTVSAVDPDRR-QSPMRYSLIGS------- 409

Query: 519 HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578
              + F IN   G I T  LLDRE  + Y L+VTA +        +  V + V+++ND+ 
Sbjct: 410 ---KMFDINGN-GTIVTTNLLDREVSAWYNLSVTATETYNVQQISSAHVYVQVLNINDHA 465

Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGL-NGRIHYELDPKDREEGSFVI---DP 634
           P F  QLY   + E+A  G  +  + A D D  + +   ++    +D    SF++     
Sbjct: 466 PEF-SQLYETYVCENAESGEIIQTISAIDRDESIEDHHFYFNHSVEDTNNSSFILTDNQD 524

Query: 635 ASGVIRTNKA-LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS 683
            + VI +N+A    +      +  +  D G PP +ST  + I++ D  DS
Sbjct: 525 NTAVILSNRAGFSLKEETVFYMIILIADNGIPPLTSTNTLTIQVCDCGDS 574



 Score =  142 bits (343), Expect = 2e-31
 Identities = 136/506 (26%), Positives = 213/506 (42%), Gaps = 31/506 (6%)

Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPPRSATATXXXXXXXXXX 361
           G  D   +ID ++G ++   +LDRE Q+ Y L     D          +           
Sbjct: 82  GTGDGSFSIDEKTGDIFAMQKLDREKQSLYILRAQVIDTTIGKAVEPESEFVIRVSDVND 141

Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR-LHYEITGGNTRGRFSITSQNGR 420
               F+   YE  + E  P GT V+ +TA DAD+     H  I     +G+   + +   
Sbjct: 142 NEPRFLDEPYEAIVPEMSPEGTFVIKVTANDADDPTSGYHARILYNLEQGQPYFSVEPTT 201

Query: 421 GLITVAQPLDFKQERRYVLTVSATDS----GGRSDTAMVQINITDANNYAPVFENAPYTA 476
           G+I ++  +D + +  Y + + A D     G  S T  + I ++D N+  P+F+ + Y  
Sbjct: 202 GVIRISSKMDRELQDTYCVIIQAKDMLGQPGALSGTTTISIKLSDINDNKPIFKESFYRF 261

Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536
           ++ E AP GTT+  + A D D+G NA++ YS+  + S       D +     Q G +   
Sbjct: 262 TISESAPSGTTIGKIMAYDDDIGENAEMDYSIEDDESQIFDIVIDNE----TQEGIVILK 317

Query: 537 KLLDRETMSGYLLTVTARDGGVPSL-------SDTTDVEISVVDVNDNEPVFKQQLYTAN 589
           K +D E  + Y + V  ++  V          + TT +++ V D  D  P F    Y   
Sbjct: 318 KKVDFEHQNHYGIRVKVKNCHVDEELAPAHVNASTTYIKVQVED-EDEPPTFLLPYYIFE 376

Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID-PASGVIRTNKALDRE 648
           I E    GT V  V A D D      + Y L       GS + D   +G I T   LDRE
Sbjct: 377 IPEGKPYGTMVGTVSAVDPD-RRQSPMRYSLI------GSKMFDINGNGTIVTTNLLDRE 429

Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
             A ++L   A +     Q S+  V++++ +IND  P F S     Y+ EN+  G  I  
Sbjct: 430 VSAWYNLSVTATETYNVQQISSAHVYVQVLNINDHAPEF-SQLYETYVCENAESGEIIQT 488

Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSN--SFSLETRQGSDKAELVTMVDLDYESPRKKYELV 766
           I A D DE       Y     +D+N  SF L   Q +    L        +     Y ++
Sbjct: 489 ISAIDRDESIEDHHFYFNHSVEDTNNSSFILTDNQDNTAVILSNRAGFSLKEETVFYMII 548

Query: 767 IRAAS--PPLWNDVRVEILVTDVNDN 790
           + A +  PPL +   + I V D  D+
Sbjct: 549 LIADNGIPPLTSTNTLTIQVCDCGDS 574



 Score =  112 bits (269), Expect = 2e-22
 Identities = 118/457 (25%), Positives = 194/457 (42%), Gaps = 56/457 (12%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVTA 67
           I V D ND+ P F  + YEA V E +  GT V+ + A D D    G +A + Y +E    
Sbjct: 134 IRVSDVNDNEPRFLDEPYEAIVPEMSPEGTFVIKVTANDADDPTSGYHARILYNLE---- 189

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
                              Q  F ++  +G +   + +DRE    Y V+++A D      
Sbjct: 190 -----------------QGQPYFSVEPTTGVIRISSKMDRELQDTYCVIIQAKDMLGQ-P 231

Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
             LS T TI + + D NDN P F E  Y  ++ E  S      I KI A D D+G N+ +
Sbjct: 232 GALSGTTTISIKLSDINDNKPIFKESFYRFTISE--SAPSGTTIGKIMAYDDDIGENAEM 289

Query: 188 RYAIIGGNTQMQFSI----DSLSGDVSLVKTLDYEQVRSYRLVIRAQ-----DGGSPSRS 238
            Y+I    +Q+ F I    ++  G V L K +D+E    Y + ++ +     +  +P+  
Sbjct: 290 DYSIEDDESQI-FDIVIDNETQEGIVILKKKVDFEHQNHYGIRVKVKNCHVDEELAPAHV 348

Query: 239 N--TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
           N  TT + + + D  D  P F    +   + E  P G  +  V A D D    + + Y++
Sbjct: 349 NASTTYIKVQVED-EDEPPTFLLPYYIFEIPEGKPYGTMVGTVSAVDPDRR-QSPMRYSL 406

Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356
                 G+    I     +G + T+  LDRE  A Y L VTAT+  +  + ++A      
Sbjct: 407 -----IGSKMFDIN---GNGTIVTTNLLDREVSAWYNLSVTATETYNVQQISSAHVYVQV 458

Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNT-RGRF 412
                    F    YE  + E+   G  + T++A D D   ED+  ++  +  +T    F
Sbjct: 459 LNINDHAPEFSQ-LYETYVCENAESGEIIQTISAIDRDESIEDHHFYFNHSVEDTNNSSF 517

Query: 413 SITSQNGRGLITVAQPLDF--KQERRYVLTVSATDSG 447
            +T       + ++    F  K+E  + + +   D+G
Sbjct: 518 ILTDNQDNTAVILSNRAGFSLKEETVFYMIILIADNG 554



 Score =  100 bits (240), Expect = 5e-19
 Identities = 87/347 (25%), Positives = 152/347 (43%), Gaps = 31/347 (8%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I + D ND+ P+F+   Y  ++ E A SGTT+  + A D DIG+NAE++Y+IE       
Sbjct: 242 IKLSDINDNKPIFKESFYRFTISESAPSGTTIGKIMAYDDDIGENAEMDYSIE------- 294

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKA----TDQASPV 126
             +D              V   + + G ++ +  +D E    Y + VK      D+    
Sbjct: 295 --DDESQIFDI-------VIDNETQEGIVILKKKVDFEHQNHYGIRVKVKNCHVDEELAP 345

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
           +   +ST  I V  ++D D  P F    Y   + E        ++  + A D D    S 
Sbjct: 346 AHVNASTTYIKVQ-VEDEDEPPTFLLPYYIFEIPE--GKPYGTMVGTVSAVDPD-RRQSP 401

Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           +RY++IG      F I+  +G +     LD E    Y L + A +  +  + ++  + + 
Sbjct: 402 MRYSLIGSK---MFDING-NGTIVTTNLLDREVSAWYNLSVTATETYNVQQISSAHVYVQ 457

Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306
           + ++ND+AP F + L++  V EN   G  I  + A D DE +     Y     + T N  
Sbjct: 458 VLNINDHAPEF-SQLYETYVCENAESGEIIQTISAIDRDESIEDHHFYFNHSVEDTNNSS 516

Query: 307 LPITIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGGDPPRSATAT 351
             +T +  +  V  S +     + +  + +++   D G PP ++T T
Sbjct: 517 FILTDNQDNTAVILSNRAGFSLKEETVFYMIILIADNGIPPLTSTNT 563



 Score = 72.1 bits (169), Expect = 2e-10
 Identities = 71/264 (26%), Positives = 128/264 (48%), Gaps = 29/264 (10%)

Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
           ++  VG   +D+  NG   ++       +GSF ID  +G I   + LDRE  + + L+A 
Sbjct: 58  TIQHVGRLRSDLD-NGNNSFQYKLLGTGDGSFSIDEKTGDIFAMQKLDREKQSLYILRAQ 116

Query: 659 AIDG----GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
            ID        P+S  VI   ++ D+ND+ P F  +     + E SP GT + ++ A+D 
Sbjct: 117 VIDTTIGKAVEPESEFVI---RVSDVNDNEPRFLDEPYEAIVPEMSPEGTFVIKVTANDA 173

Query: 715 DE---GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA-- 769
           D+   G +A + Y+++ G     FS+E   G  +  + + +D + +     Y ++I+A  
Sbjct: 174 DDPTSGYHARILYNLEQGQPY--FSVEPTTGVIR--ISSKMDRELQDT---YCVIIQAKD 226

Query: 770 --ASP-PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTD 825
               P  L     + I ++D+NDN P+ K+    F    +  P G   G++ AYD D+ +
Sbjct: 227 MLGQPGALSGTTTISIKLSDINDNKPIFKESFYRF-TISESAPSGTTIGKIMAYDDDIGE 285

Query: 826 --KLQYRILSGNNA--NLILLNET 845
             ++ Y I    +   ++++ NET
Sbjct: 286 NAEMDYSIEDDESQIFDIVIDNET 309



 Score = 41.1 bits (92), Expect = 0.43
 Identities = 20/44 (45%), Positives = 26/44 (59%), Gaps = 1/44 (2%)

Query: 8   HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD 51
           H  + VL+ NDH+P F  Q YE  V E A SG  + T+ A D+D
Sbjct: 453 HVYVQVLNINDHAPEFS-QLYETYVCENAESGEIIQTISAIDRD 495


>UniRef50_A4GJB0 Cluster: Hypothetical cadherin domain containing
            protein; n=1; uncultured marine bacterium EB0_49D07|Rep:
            Hypothetical cadherin domain containing protein -
            uncultured marine bacterium EB0_49D07
          Length = 2204

 Score =  166 bits (403), Expect = 9e-39
 Identities = 169/603 (28%), Positives = 272/603 (45%), Gaps = 64/603 (10%)

Query: 88   DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
            D F ID  SG +   + LD E    Y + V A D         +ST  I +++ D N+  
Sbjct: 662  DNFSIDA-SGNITLASGLDYETATSYELTVVADDGT------YASTEVITISVADVNEAP 714

Query: 148  PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
               S   +   ++   + T    IA   +TD + GA   I Y++ G  ++  FS+ S  G
Sbjct: 715  TLSSTVAFNTFLENTATGT---TIATSSSTDPEAGA---ISYSLSGTGSE-NFSVSS-DG 766

Query: 208  DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
             V+L   LDYE    Y + + A DG + S S T  L IN+ D+N+ AP    SL   + +
Sbjct: 767  TVTLASALDYETTTEYAITLTASDGAN-SVSET--LTINVGDINE-APSLTNSLAASTFA 822

Query: 268  ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
            ENV  G +I    A D +   +  +TY+++    TG+ +  +     +G +  S  LD E
Sbjct: 823  ENVSTGTTIATASASDPE---SQAITYSLSG---TGSENFAVD---SAGNITLSSALDYE 873

Query: 328  TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387
            T   Y L +TA+DG +    +T+                +     + L+E    GT V T
Sbjct: 874  TTTSYSLTLTASDGAN----STSNTINISVDDVTELSIALASS-SISLSEAATSGTSVTT 928

Query: 388  LTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447
             TAT  D    + Y ++G ++  +FS++S    G IT A  LD++    Y LT++ATD G
Sbjct: 929  -TATTTDGSATVTYSLSGTDS-DKFSVSSN---GTITTAASLDYETTTSYSLTLTATD-G 982

Query: 448  GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507
              + T  + INITD +       N    +   E+   GT+++  SA+    G    ++YS
Sbjct: 983  TNTVTDSLTINITDVDL---TVTNTLAASGQAENISTGTSIMTASAS----GAEGTMSYS 1035

Query: 508  LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567
            ++           D +F IN  TG +T    LD ET + +  TVTA D GV ++  T + 
Sbjct: 1036 ITDS---------DNKFSINSSTGEVTLANALDYETKTSHTFTVTATD-GVTTV--TEEF 1083

Query: 568  EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627
             +SV D+  N          A + E +  GTSV     ++ D   +  + Y L       
Sbjct: 1084 TLSVTDMIINTLAVSLANSGAALAESSSSGTSVGSSSISNPD---SETVSYSL--SGTGS 1138

Query: 628  GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687
             +F +D +SG + TN  LD E+  ++ L   A  GG     +  +    +E++  +   +
Sbjct: 1139 SNFAVD-SSGNVTTNATLDFETAKSYSLTLTATAGGNTTTDAFTVNVGNVEELESAVLRY 1197

Query: 688  ESD 690
             +D
Sbjct: 1198 SAD 1200



 Score =  147 bits (356), Expect = 4e-33
 Identities = 170/603 (28%), Positives = 275/603 (45%), Gaps = 72/603 (11%)

Query: 157  VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLD 216
            V+V E  +V    V+A   ATD +    +A+ Y++  G T  +    S +G+V+L   LD
Sbjct: 531  VNVSE--TVPAGTVVATFSATDPE---GNALTYSL--GGTGSELMTVSETGEVTLTGNLD 583

Query: 217  YEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP-RFYTSLFQESVSENVPIGYS 275
            +E   +  +V+   DG     +NTT   I I  +ND+ P     +L   S +E   +G +
Sbjct: 584  FETNSTLVMVLEVSDG-----TNTTIEEITINVINDDEPATIAATLSAASFAETSAVGAA 638

Query: 276  IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL 335
            I  + A D +    + + Y+++    TG+ +  I     SG +  +  LD ET   Y+L 
Sbjct: 639  IASINATDPE---GSAMNYSLSG---TGSDNFSI---DASGNITLASGLDYETATSYELT 689

Query: 336  VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395
            V A DG     ++T                     +   L E+   GT + T ++TD  E
Sbjct: 690  VVADDG---TYASTEVITISVADVNEAPTLSSTVAFNTFL-ENTATGTTIATSSSTD-PE 744

Query: 396  DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMV 455
               + Y ++G  +   FS++S    G +T+A  LD++    Y +T++A+D G  S +  +
Sbjct: 745  AGAISYSLSGTGSE-NFSVSSD---GTVTLASALDYETTTEYAITLTASD-GANSVSETL 799

Query: 456  QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515
             IN+ D N  AP   N+   ++  E+   GTT+   SA+D +   +  ITYSLS   S  
Sbjct: 800  TINVGDINE-APSLTNSLAASTFAENVSTGTTIATASASDPE---SQAITYSLSGTGS-- 853

Query: 516  AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575
                  + F ++   G IT +  LD ET + Y LT+TA D G  S S+T  + ISV DV 
Sbjct: 854  ------ENFAVD-SAGNITLSSALDYETTTSYSLTLTASD-GANSTSNT--INISVDDVT 903

Query: 576  DNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA 635
            +          + ++ E A  GTSV+   AT  D   +  + Y L   D ++ S     +
Sbjct: 904  ELSIALASS--SISLSEAATSGTSVTTT-ATTTDG--SATVTYSLSGTDSDKFSV---SS 955

Query: 636  SGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695
            +G I T  +LD E+  ++ L   A D GT   + ++ ++I   D+  +  +  S      
Sbjct: 956  NGTITTAASLDYETTTSYSLTLTATD-GTNTVTDSLTINITDVDLTVTNTLAASG----- 1009

Query: 696  ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755
             +EN   GT+I    A     G    + YSI   D  N FS+ +  G    E+     LD
Sbjct: 1010 QAENISTGTSIMTASA----SGAEGTMSYSIT--DSDNKFSINSSTG----EVTLANALD 1059

Query: 756  YES 758
            YE+
Sbjct: 1060 YET 1062



 Score =  128 bits (309), Expect = 2e-27
 Identities = 163/660 (24%), Positives = 277/660 (41%), Gaps = 75/660 (11%)

Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
           D  +N     T   QE+  E  PI + +   +  +  +    +++ T       G  +  
Sbjct: 386 DSTENVTEEVTETTQETTVEVAPI-FEVEASEVVENVDENTTDISLTQFAIVNPGEQNYT 444

Query: 309 ITIDPRSGWVYTSGQ----------LDRETQAKYQLLVT-ATDGGDPPRSATATXXXXXX 357
           +TI+      +T  Q          LD E+Q   +L VT  +D GD    A A       
Sbjct: 445 VTIEGEGSEAFTYNQETNSLEVIQELDHESQESVELTVTFVSDNGDTQELALALDVTDVD 504

Query: 358 XXX--------XXXXXFMPGQY---EVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG 406
                            + G+    +V ++E  P GT V T +ATD  E N L Y +  G
Sbjct: 505 EAVVLAVEPVNTISEVAISGELIANQVNVSETVPAGTVVATFSATD-PEGNALTYSL--G 561

Query: 407 NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYA 466
            T       S+ G   +T+   LDF+     V+ +  +D    ++T + +I I   N+  
Sbjct: 562 GTGSELMTVSETGE--VTLTGNLDFETNSTLVMVLEVSDG---TNTTIEEITINVINDDE 616

Query: 467 PVFENAPYTASVF-EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525
           P    A  +A+ F E + +G  +  ++ATD +    + + YSLS   S+         F 
Sbjct: 617 PATIAATLSAASFAETSAVGAAIASINATDPE---GSAMNYSLSGTGSD--------NFS 665

Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585
           I+  +G IT    LD ET + Y LTV A DG   + + T  + ISV DVN+  P     +
Sbjct: 666 ID-ASGNITLASGLDYETATSYELTVVADDG---TYASTEVITISVADVNE-APTLSSTV 720

Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645
                +E+   GT+++   +TD +    G I Y L     E  S   D   G +    AL
Sbjct: 721 AFNTFLENTATGTTIATSSSTDPEA---GAISYSLSGTGSENFSVSSD---GTVTLASAL 774

Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
           D E+   + +   A DG     S +  + I + DIN++P +  S   + + +EN   GTT
Sbjct: 775 DYETTTEYAITLTASDGA---NSVSETLTINVGDINEAPSLTNSLAASTF-AENVSTGTT 830

Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYE 764
           I    A DP+   +  + YS+  G  S +F++      D A  +T+   LDYE+    Y 
Sbjct: 831 IATASASDPE---SQAITYSL-SGTGSENFAV------DSAGNITLSSALDYET-TTSYS 879

Query: 765 LVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVT 824
           L + A+         + I V DV + +  +    I   +  +    G      A   D +
Sbjct: 880 LTLTASDGANSTSNTINISVDDVTELSIALASSSI---SLSEAATSGTSVTTTATTTDGS 936

Query: 825 DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884
             + Y  LSG +++   ++ + G++T +  L+       ++ ++ TDG N +   + +++
Sbjct: 937 ATVTYS-LSGTDSDKFSVS-SNGTITTAASLDYETTTSYSLTLTATDGTNTVTDSLTINI 994



 Score =  117 bits (281), Expect = 5e-24
 Identities = 136/546 (24%), Positives = 243/546 (44%), Gaps = 60/546 (10%)

Query: 374 ELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ 433
           E+ E+    T  ++LT          +Y +T     G  + T       + V Q LD + 
Sbjct: 416 EVVENVDENTTDISLTQFAIVNPGEQNYTVTIEG-EGSEAFTYNQETNSLEVIQELDHES 474

Query: 434 ERRYVLTVSATDSGGRSDTAMVQINITDA-----------NNYAPVFENAPYTAS---VF 479
           +    LTV+     G +    + +++TD            N  + V  +    A+   V 
Sbjct: 475 QESVELTVTFVSDNGDTQELALALDVTDVDEAVVLAVEPVNTISEVAISGELIANQVNVS 534

Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
           E  P GT V   SATD +   NA +TYSL    S         + +   +TG +T    L
Sbjct: 535 ETVPAGTVVATFSATDPEG--NA-LTYSLGGTGS---------ELMTVSETGEVTLTGNL 582

Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV-FKQQLYTANIMEDALVGT 598
           D ET S  ++ +   DG     ++TT  EI++  +ND+EP      L  A+  E + VG 
Sbjct: 583 DFETNSTLVMVLEVSDG-----TNTTIEEITINVINDDEPATIAATLSAASFAETSAVGA 637

Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658
           +++ + ATD +      ++Y L     +  +F ID ASG I     LD E+  +++L  V
Sbjct: 638 AIASINATDPE---GSAMNYSLSGTGSD--NFSID-ASGNITLASGLDYETATSYELTVV 691

Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
           A DG     +ST ++ I + D+N++P +  +     ++ EN+  GTTI    + DP+ G 
Sbjct: 692 ADDG---TYASTEVITISVADVNEAPTLSSTVAFNTFL-ENTATGTTIATSSSTDPEAG- 746

Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVIRAASPPLWND 777
              + YS+ G    N FS+ +  G+     VT+   LDYE+  + Y + + A+       
Sbjct: 747 --AISYSLSGTGSEN-FSVSS-DGT-----VTLASALDYETTTE-YAITLTASDGANSVS 796

Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNA 837
             + I V D+N+ AP + +  +  + + +    G      +     +  + Y +    + 
Sbjct: 797 ETLTINVGDINE-APSLTN-SLAASTFAENVSTGTTIATASASDPESQAITYSLSGTGSE 854

Query: 838 NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE-EMLLNSI 896
           N  +  ++ G++TLS  L+       ++ ++ +DG N     + +SV  +TE  + L S 
Sbjct: 855 NFAV--DSAGNITLSSALDYETTTSYSLTLTASDGANSTSNTINISVDDVTELSIALASS 912

Query: 897 TVRLND 902
           ++ L++
Sbjct: 913 SISLSE 918


>UniRef50_UPI000065CB52 Cluster: Homolog of Homo sapiens
           "Protocadherin 20; n=2; Clupeocephala|Rep: Homolog of
           Homo sapiens "Protocadherin 20 - Takifugu rubripes
          Length = 406

 Score =  164 bits (399), Expect = 3e-38
 Identities = 127/419 (30%), Positives = 192/419 (45%), Gaps = 24/419 (5%)

Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268
           V +   LD E    Y   I A+DGG+P       L I I DVNDN P+F  S    ++  
Sbjct: 5   VIVTDALDRETQAEYITDIIAEDGGTPPLLGAATLKIVIADVNDNCPQFTESQINVTLHG 64

Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328
           N   G  + R+ A+D D G NA+++Y  +++       L   +D  +G +  + + D  T
Sbjct: 65  NASKGTHLARLHAFDPDLGANAQISYAYSERVPKDTRSL-FHLDRITGVIKLARKTDTGT 123

Query: 329 QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388
              Y+L V A   G  P  AT                F     ++ + E+  P T +  L
Sbjct: 124 ATFYKLTVLANGPGCIPAVAT----IHVLDENDNAPVFEKSLVKISIDENNSPNTFLAQL 179

Query: 389 TATDADEDNRLH-YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447
            ATD D + R     + GG+    F +      G++ VA  LD +++  Y   V A D G
Sbjct: 180 QATDQDSEGRGEVIYLLGGDAPEIFIL--DRVTGVLIVAASLDREEKETYRFIVRAVDQG 237

Query: 448 --GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505
              R   A V + + D N+ +P F N  +T  V E+ P    + V+S TD+D G N  + 
Sbjct: 238 TPRRESIATVVLTVQDRNDNSPRFLNKDFTFFVPENFPGYGEIGVISVTDADAGENGWVA 297

Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTT 565
            S         + +    F+I+   G +     LDRE    Y L + A DGG P+LS  T
Sbjct: 298 LS---------IINGSDTFMIDTGRGTLRAKTSLDREQQGTYQLWIEAADGGEPALSCIT 348

Query: 566 DVEISVVDVNDNEP--VFKQ--QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620
            + + ++DVNDN P  +F Q  Q Y   ++ + L GTS+++V A D D G+N  I Y +
Sbjct: 349 MITVLLLDVNDNPPTVLFPQSNQSYML-VLPNTLPGTSITEVYAVDRDTGMNAVIAYSI 406



 Score =  164 bits (398), Expect = 4e-38
 Identities = 128/418 (30%), Positives = 187/418 (44%), Gaps = 23/418 (5%)

Query: 317 WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376
           +V  +  LDRETQA+Y   + A DGG PP    AT              F   Q  V L 
Sbjct: 4   FVIVTDALDRETQAEYITDIIAEDGGTPPLLGAATLKIVIADVNDNCPQFTESQINVTLH 63

Query: 377 EDEPPGTPVVTLTATDAD--EDNRLHY---EITGGNTRGRFSITSQNGRGLITVAQPLDF 431
            +   GT +  L A D D   + ++ Y   E    +TR  F +      G+I +A+  D 
Sbjct: 64  GNASKGTHLARLHAFDPDLGANAQISYAYSERVPKDTRSLFHL--DRITGVIKLARKTDT 121

Query: 432 KQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491
                Y LTV A   G     A+  I++ D N+ APVFE +    S+ E+    T +  +
Sbjct: 122 GTATFYKLTVLANGPG--CIPAVATIHVLDENDNAPVFEKSLVKISIDENNSPNTFLAQL 179

Query: 492 SATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTV 551
            ATD D     ++ Y L  +          + F+++  TG +     LDRE    Y   V
Sbjct: 180 QATDQDSEGRGEVIYLLGGDA--------PEIFILDRVTGVLIVAASLDREEKETYRFIV 231

Query: 552 TARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG 611
            A D G P       V ++V D NDN P F  + +T  + E+      +  +  TDAD G
Sbjct: 232 RAVDQGTPRRESIATVVLTVQDRNDNSPRFLNKDFTFFVPENFPGYGEIGVISVTDADAG 291

Query: 612 LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671
            NG +   +        +F+ID   G +R   +LDRE   T+ L   A DGG P  S   
Sbjct: 292 ENGWVALSI---INGSDTFMIDTGRGTLRAKTSLDREQQGTYQLWIEAADGGEPALSCIT 348

Query: 672 IVHIKIEDINDSPPVF---ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
           ++ + + D+ND+PP     +S+     +  N+  GT+I E+ A D D G NAV+ YSI
Sbjct: 349 MITVLLLDVNDNPPTVLFPQSNQSYMLVLPNTLPGTSITEVYAVDRDTGMNAVIAYSI 406



 Score =  158 bits (384), Expect = 2e-36
 Identities = 121/378 (32%), Positives = 186/378 (49%), Gaps = 24/378 (6%)

Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFE 480
           + V   LD + +  Y+  + A D G       A ++I I D N+  P F  +    ++  
Sbjct: 5   VIVTDALDRETQAEYITDIIAEDGGTPPLLGAATLKIVIADVNDNCPQFTESQINVTLHG 64

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           +A  GT +  + A D D+G NAQI+Y+ S  +  +  +     F ++  TG I   +  D
Sbjct: 65  NASKGTHLARLHAFDPDLGANAQISYAYSERVPKDTRS----LFHLDRITGVIKLARKTD 120

Query: 541 RETMSGYLLTVTARDGG-VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599
             T + Y LTV A   G +P+++      I V+D NDN PVF++ L   +I E+    T 
Sbjct: 121 TGTATFYKLTVLANGPGCIPAVAT-----IHVLDENDNAPVFEKSLVKISIDENNSPNTF 175

Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659
           ++Q+ ATD D    G + Y L     E   F++D  +GV+    +LDRE   T+     A
Sbjct: 176 LAQLQATDQDSEGRGEVIYLLGGDAPE--IFILDRVTGVLIVAASLDREEKETYRFIVRA 233

Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
           +D GTP + S   V + ++D ND+ P F +   TF++ EN P    IG I   D D G N
Sbjct: 234 VDQGTPRRESIATVVLTVQDRNDNSPRFLNKDFTFFVPENFPGYGEIGVISVTDADAGEN 293

Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWN 776
             V  SI  G D  +F ++T +G+ +A+      LD E  +  Y+L I AA    P L  
Sbjct: 294 GWVALSIINGSD--TFMIDTGRGTLRAK----TSLDREQ-QGTYQLWIEAADGGEPALSC 346

Query: 777 DVRVEILVTDVNDNAPVM 794
              + +L+ DVNDN P +
Sbjct: 347 ITMITVLLLDVNDNPPTV 364



 Score =  149 bits (362), Expect = 8e-34
 Identities = 106/340 (31%), Positives = 163/340 (47%), Gaps = 36/340 (10%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI-ELVTAD 68
           +I + D ND+ P F   Q   ++   AS GT +  L A D D+G NA++ Y   E V  D
Sbjct: 40  KIVIADVNDNCPQFTESQINVTLHGNASKGTHLARLHAFDPDLGANAQISYAYSERVPKD 99

Query: 69  TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128
           T                 + +F +D  +G +      D      Y + V A         
Sbjct: 100 T-----------------RSLFHLDRITGVIKLARKTDTGTATFYKLTVLANGPGC---- 138

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
            + + ATIHV  +D+NDN P F +    +S+DE+ S   N  +A+++ATD D      + 
Sbjct: 139 -IPAVATIHV--LDENDNAPVFEKSLVKISIDENNS--PNTFLAQLQATDQDSEGRGEVI 193

Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248
           Y ++GG+    F +D ++G + +  +LD E+  +YR ++RA D G+P R +   +++ ++
Sbjct: 194 Y-LLGGDAPEIFILDRVTGVLIVAASLDREEKETYRFIVRAVDQGTPRRESIATVVLTVQ 252

Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRV-QAYDADEGVNAELTYTMTDKDYTGNVDL 307
           D NDN+PRF    F   V EN P GY  + V    DAD G N  +  ++ +   T     
Sbjct: 253 DRNDNSPRFLNKDFTFFVPENFP-GYGEIGVISVTDADAGENGWVALSIINGSDT----- 306

Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRS 347
              ID   G +     LDRE Q  YQL + A DGG+P  S
Sbjct: 307 -FMIDTGRGTLRAKTSLDREQQGTYQLWIEAADGGEPALS 345



 Score =  149 bits (360), Expect = 1e-33
 Identities = 120/414 (28%), Positives = 185/414 (44%), Gaps = 26/414 (6%)

Query: 104 SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI 163
           +LDRE  A Y   + A D  +P    L   AT+ + I D NDN PQF+E    V++  + 
Sbjct: 10  ALDRETQAEYITDIIAEDGGTPP---LLGAATLKIVIADVNDNCPQFTESQINVTLHGNA 66

Query: 164 SVTDNPVIAKIKATDADVGANSAIRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQV 220
           S   +  +A++ A D D+GAN+ I YA    +  +T+  F +D ++G + L +  D    
Sbjct: 67  SKGTH--LARLHAFDPDLGANAQISYAYSERVPKDTRSLFHLDRITGVIKLARKTDTGTA 124

Query: 221 RSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQ 280
             Y+L + A   G      T    I++ D NDNAP F  SL + S+ EN      + ++Q
Sbjct: 125 TFYKLTVLANGPGCIPAVAT----IHVLDENDNAPVFEKSLVKISIDENNSPNTFLAQLQ 180

Query: 281 AYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD 340
           A D D     E+ Y +      G+      +D  +G +  +  LDRE +  Y+ +V A D
Sbjct: 181 ATDQDSEGRGEVIYLL-----GGDAPEIFILDRVTGVLIVAASLDREEKETYRFIVRAVD 235

Query: 341 GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH 400
            G P R + AT              F+   +   + E+ P    +  ++ TDAD      
Sbjct: 236 QGTPRRESIATVVLTVQDRNDNSPRFLNKDFTFFVPENFPGYGEIGVISVTDADAGENGW 295

Query: 401 YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQIN 458
             ++  N    F I    GRG +     LD +Q+  Y L + A D G    S   M+ + 
Sbjct: 296 VALSIINGSDTFMI--DTGRGTLRAKTSLDREQQGTYQLWIEAADGGEPALSCITMITVL 353

Query: 459 ITDANNYAPVF----ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508
           + D N+  P       N  Y   +    P GT++  V A D D G+NA I YS+
Sbjct: 354 LLDVNDNPPTVLFPQSNQSYMLVLPNTLP-GTSITEVYAVDRDTGMNAVIAYSI 406



 Score =  143 bits (347), Expect = 5e-32
 Identities = 109/292 (37%), Positives = 148/292 (50%), Gaps = 36/292 (12%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I+VLD ND++PVFE    + S+ E  S  T +  L+ATDQD     EV Y   L+  D  
Sbjct: 145 IHVLDENDNAPVFEKSLVKISIDENNSPNTFLAQLQATDQDSEGRGEVIY---LLGGDA- 200

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
            PE               +F +D  +G L+  ASLDRE+   Y  +V+A DQ +P   R 
Sbjct: 201 -PE---------------IFILDRVTGVLIVAASLDREEKETYRFIVRAVDQGTP---RR 241

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
            S AT+ + + D NDN P+F  K +T  V E+        I  I  TDAD G N  +  +
Sbjct: 242 ESIATVVLTVQDRNDNSPRFLNKDFTFFVPENFPGYGE--IGVISVTDADAGENGWVALS 299

Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250
           II G+    F ID+  G +    +LD EQ  +Y+L I A DGG P+ S  T + + + DV
Sbjct: 300 IINGSDT--FMIDTGRGTLRAKTSLDREQQGTYQLWIEAADGGEPALSCITMITVLLLDV 357

Query: 251 NDNAPRFYTSLFQES------VSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
           NDN P   T LF +S      V  N   G SI  V A D D G+NA + Y++
Sbjct: 358 NDNPP---TVLFPQSNQSYMLVLPNTLPGTSITEVYAVDRDTGMNAVIAYSI 406



 Score =  124 bits (298), Expect = 5e-26
 Identities = 100/353 (28%), Positives = 160/353 (45%), Gaps = 25/353 (7%)

Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589
           T  +     LDRET + Y+  + A DGG P L     ++I + DVNDN P F +      
Sbjct: 2   TPFVIVTDALDRETQAEYITDIIAEDGGTPPLLGAATLKIVIADVNDNCPQFTESQINVT 61

Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHY---ELDPKDREEGSFVIDPASGVIRTNKALD 646
           +  +A  GT ++++ A D D+G N +I Y   E  PKD     F +D  +GVI+  +  D
Sbjct: 62  LHGNASKGTHLARLHAFDPDLGANAQISYAYSERVPKD-TRSLFHLDRITGVIKLARKTD 120

Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706
             +   + L  +A   G  P  +T    I + D ND+ PVFE   +   I EN+   T +
Sbjct: 121 TGTATFYKLTVLANGPGCIPAVAT----IHVLDENDNAPVFEKSLVKISIDENNSPNTFL 176

Query: 707 GEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765
            +++A D D EG   V++  + GGD    F L+   G     L+    LD E  ++ Y  
Sbjct: 177 AQLQATDQDSEGRGEVIY--LLGGDAPEIFILDRVTG----VLIVAASLDREE-KETYRF 229

Query: 766 VIRA---ASPPLWNDVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFP-VGPFGRVPAY 819
           ++RA    +P   +   V + V D NDN+P  + KDF        + FP  G  G +   
Sbjct: 230 IVRAVDQGTPRRESIATVVLTVQDRNDNSPRFLNKDFTFF---VPENFPGYGEIGVISVT 286

Query: 820 DADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
           DAD  +     +   N ++  +++   G++     L+        + +   DG
Sbjct: 287 DADAGENGWVALSIINGSDTFMIDTGRGTLRAKTSLDREQQGTYQLWIEAADG 339


>UniRef50_Q4RZD6 Cluster: Chromosome undetermined SCAF14942, whole
            genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
            Chromosome undetermined SCAF14942, whole genome shotgun
            sequence - Tetraodon nigroviridis (Green puffer)
          Length = 630

 Score =  163 bits (397), Expect = 5e-38
 Identities = 157/551 (28%), Positives = 245/551 (44%), Gaps = 51/551 (9%)

Query: 521  DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580
            + +F+I+  TG I   + LDRE  + +   V A D G   L+  TDV I+V D+NDNEPV
Sbjct: 2    ESEFIIDEVTGKIYAQRTLDREERAVWRFVVLATDEGGEGLTGFTDVIINVWDINDNEPV 61

Query: 581  FK-QQLYTANIMEDALVGTSVSQVGATDAD---VGLNGRIHYEL-------DPKDREEGS 629
            F        ++ E++LVGTSV ++ ATD D   VG N  + Y +       +  DR   S
Sbjct: 62   FTCAPSCHGSVAENSLVGTSVMEMTATDLDDSAVGQNAVLSYRIMGSLDGANFHDRGVPS 121

Query: 630  ----FVIDPASGVIRTN-KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP 684
                F I+P++G I    + LDRE V ++ +   A DGG     +T  + IK  D+ND  
Sbjct: 122  SSEMFTINPSTGTISVAMEGLDREQVESYLIFVEARDGGGLAGIATATIQIK--DLNDHA 179

Query: 685  PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD 744
            P F  D     ISEN+     + E+ A D D G NA + +S+  GD    F + + +   
Sbjct: 180  PKFTDDTCAVQISENTETNAEVLELAAEDRDIGENAQLTFSVVAGDQEQKFYIVSHKQEQ 239

Query: 745  KAELVTMVDLDYE-SPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN 803
            +  L     LDYE    +++ L ++     L     +  L T   +     K+F I    
Sbjct: 240  RGTLRLKKKLDYERHGEQRFNLTLK---DNLNGTATLTALRTFDRER---QKEFFIPV-- 291

Query: 804  YKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLA 863
                 P    G+V + D D  D   Y +  GN  N  +LN+ TG + +    NT  P   
Sbjct: 292  IMSRLPTTVIGKVFSPDPDEWDNKTY-VFEGNVPNYFVLNKRTGFLIIKE--NT-PPGTY 347

Query: 864  TMEVSVTDGV-NEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLG------FF 916
              +V V D V  +  + + + VR + +E + NS ++RL D+TA +F+    G        
Sbjct: 348  QFQVRVADDVWPDAVSSVSVHVRELRDEAIYNSGSLRLADITAREFIELRRGQRSRYDLL 407

Query: 917  IDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLR 976
             D L+ ++  P  ++ IFS+   TDV   +L+V F+ R     VG     S    P  + 
Sbjct: 408  GDFLSEMLSVPPNDVNIFSL---TDVKDRMLDVRFAVR-----VG-----SSFLQPEKMH 454

Query: 977  ERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPI 1036
              +  H+  L     + V     + C    C     C  VL   +    V+  ++    +
Sbjct: 455  GYLAAHKQKLQSFLQIVVFQIRVDECPSSGCAGASGCTNVLNVRDTPMVVDCGTMSLVSV 514

Query: 1037 YPVTSFTCQCP 1047
               ++  C CP
Sbjct: 515  TLESTAVCSCP 525



 Score =  100 bits (239), Expect = 7e-19
 Identities = 81/278 (29%), Positives = 137/278 (49%), Gaps = 23/278 (8%)

Query: 197 QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256
           + +F ID ++G +   +TLD E+   +R V+ A D G    +  T ++IN+ D+NDN P 
Sbjct: 2   ESEFIIDEVTGKIYAQRTLDREERAVWRFVVLATDEGGEGLTGFTDVIINVWDINDNEPV 61

Query: 257 FYTS-LFQESVSENVPIGYSIVRVQAYDADE---GVNAELTYTMT---------DKDYTG 303
           F  +     SV+EN  +G S++ + A D D+   G NA L+Y +          D+    
Sbjct: 62  FTCAPSCHGSVAENSLVGTSVMEMTATDLDDSAVGQNAVLSYRIMGSLDGANFHDRGVPS 121

Query: 304 NVDLPITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
           + ++  TI+P +G +  + + LDRE    Y + V A DGG     ATAT           
Sbjct: 122 SSEM-FTINPSTGTISVAMEGLDREQVESYLIFVEARDGGGLAGIATAT--IQIKDLNDH 178

Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITS--QN 418
              F      V+++E+      V+ L A D D  E+ +L + +  G+   +F I S  Q 
Sbjct: 179 APKFTDDTCAVQISENTETNAEVLELAAEDRDIGENAQLTFSVVAGDQEQKFYIVSHKQE 238

Query: 419 GRGLITVAQPLDFKQ--ERRYVLTVSATDSGGRSDTAM 454
            RG + + + LD+++  E+R+ LT+    +G  + TA+
Sbjct: 239 QRGTLRLKKKLDYERHGEQRFNLTLKDNLNGTATLTAL 276



 Score = 96.3 bits (229), Expect = 1e-17
 Identities = 79/278 (28%), Positives = 136/278 (48%), Gaps = 24/278 (8%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F ID  +G +  + +LDRE+ A +  +V ATD+     + L+    + +N+ D NDN P 
Sbjct: 5   FIIDEVTGKIYAQRTLDREERAVWRFVVLATDEG---GEGLTGFTDVIINVWDINDNEPV 61

Query: 150 FS-EKTYTVSVDEDISVTDNPVIAKIKATDAD---VGANSAIRYAIIGG----------- 194
           F+   +   SV E+  V  +  + ++ ATD D   VG N+ + Y I+G            
Sbjct: 62  FTCAPSCHGSVAENSLVGTS--VMEMTATDLDDSAVGQNAVLSYRIMGSLDGANFHDRGV 119

Query: 195 -NTQMQFSIDSLSGDVSL-VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252
            ++   F+I+  +G +S+ ++ LD EQV SY + + A+DGG  +   T    I I+D+ND
Sbjct: 120 PSSSEMFTINPSTGTISVAMEGLDREQVESYLIFVEARDGGGLAGIATA--TIQIKDLND 177

Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312
           +AP+F        +SEN      ++ + A D D G NA+LT+++   D      +     
Sbjct: 178 HAPKFTDDTCAVQISENTETNAEVLELAAEDRDIGENAQLTFSVVAGDQEQKFYIVSHKQ 237

Query: 313 PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350
            + G +    +LD E   + +  +T  D  +   + TA
Sbjct: 238 EQRGTLRLKKKLDYERHGEQRFNLTLKDNLNGTATLTA 275



 Score = 93.5 bits (222), Expect = 8e-17
 Identities = 70/230 (30%), Positives = 114/230 (49%), Gaps = 23/230 (10%)

Query: 11  INVLDCNDHSPVFEMQ-QYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVT 66
           INV D ND+ PVF        SV E +  GT+V+ + ATD D   +G+NA + Y I + +
Sbjct: 50  INVWDINDNEPVFTCAPSCHGSVAENSLVGTSVMEMTATDLDDSAVGQNAVLSYRI-MGS 108

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLVKATDQASP 125
            D  N  D             ++F I+  +G + +    LDRE+V  Y + V+A D    
Sbjct: 109 LDGANFHDRGVPSSS------EMFTINPSTGTISVAMEGLDREQVESYLIFVEARDGGG- 161

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
               L+  AT  + I D ND+ P+F++ T  V + E+     N  + ++ A D D+G N+
Sbjct: 162 ----LAGIATATIQIKDLNDHAPKFTDDTCAVQISENTET--NAEVLELAAEDRDIGENA 215

Query: 186 AIRYAIIGGNTQMQFSIDS----LSGDVSLVKTLDYEQVRSYRLVIRAQD 231
            + ++++ G+ + +F I S      G + L K LDYE+    R  +  +D
Sbjct: 216 QLTFSVVAGDQEQKFYIVSHKQEQRGTLRLKKKLDYERHGEQRFNLTLKD 265



 Score = 85.0 bits (201), Expect = 3e-14
 Identities = 98/385 (25%), Positives = 158/385 (41%), Gaps = 40/385 (10%)

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATD-GGDPPRSATATXXXXXXXXXXXXXXFMPG 369
           ID  +G +Y    LDRE +A ++ +V ATD GG+     T                    
Sbjct: 7   IDEVTGKIYAQRTLDREERAVWRFVVLATDEGGEGLTGFTDVIINVWDINDNEPVFTCAP 66

Query: 370 QYEVELAEDEPPGTPVVTLTATDADED----NR-LHYEITGGNTRGRFS----------I 414
                +AE+   GT V+ +TATD D+     N  L Y I G      F            
Sbjct: 67  SCHGSVAENSLVGTSVMEMTATDLDDSAVGQNAVLSYRIMGSLDGANFHDRGVPSSSEMF 126

Query: 415 TSQNGRGLITVA-QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAP 473
           T     G I+VA + LD +Q   Y++ V A D GG +  A   I I D N++AP F +  
Sbjct: 127 TINPSTGTISVAMEGLDREQVESYLIFVEARDGGGLAGIATATIQIKDLNDHAPKFTDDT 186

Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA--VAHHDQQFVINPQTG 531
               + E+      VL ++A D D+G NAQ+T+S+ +    +   +  H Q+     Q G
Sbjct: 187 CAVQISENTETNAEVLELAAEDRDIGENAQLTFSVVAGDQEQKFYIVSHKQE-----QRG 241

Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
            +   K LD E        +T +D    +L+ T    ++ +   D E   +Q+ +   ++
Sbjct: 242 TLRLKKKLDYERHGEQRFNLTLKD----NLNGT--ATLTALRTFDRE---RQKEFFIPVI 292

Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA 651
              L  T + +V + D D   N    +E          FV++  +G +      +     
Sbjct: 293 MSRLPTTVIGKVFSPDPDEWDNKTYVFE----GNVPNYFVLNKRTGFLIIK---ENTPPG 345

Query: 652 THDLKAVAIDGGTPPQSSTVIVHIK 676
           T+  +    D   P   S+V VH++
Sbjct: 346 TYQFQVRVADDVWPDAVSSVSVHVR 370


>UniRef50_P33151 Cluster: Cadherin-5 precursor; n=34; Tetrapoda|Rep:
           Cadherin-5 precursor - Homo sapiens (Human)
          Length = 784

 Score =  163 bits (396), Expect = 6e-38
 Identities = 164/550 (29%), Positives = 253/550 (46%), Gaps = 51/550 (9%)

Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYE 218
           +DE+ + +    + KIK++   V   +A +Y + G      F +D+ +GDV  ++ LD E
Sbjct: 56  IDEEKNTSLPHHVGKIKSS---VSRKNA-KYLLKGEYVGKVFRVDAETGDVFAIERLDRE 111

Query: 219 QVRSYRL--VIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSI 276
            +  Y L  VI  +D G  +    +   I + DVNDN P F   LF  SV E+  +G S+
Sbjct: 112 NISEYHLTAVIVDKDTGE-NLETPSSFTIKVHDVNDNWPVFTHRLFNASVPESSAVGTSV 170

Query: 277 VRVQAYDADE---GVNAELTY-TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332
           + V A DAD+   G +A + Y  +  K+Y         ID     +  +  LDRE QA+Y
Sbjct: 171 ISVTAVDADDPTVGDHASVMYQILKGKEY-------FAIDNSGRIITITKSLDREKQARY 223

Query: 333 QLLVTATDG-GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTAT 391
           +++V A D  G    S TAT              F   +Y   + ED   GT V +L   
Sbjct: 224 EIVVEARDAQGLRGDSGTATVLVTLQDINDNFPFFTQTKYTFVVPEDTRVGTSVGSLFVE 283

Query: 392 DADE-DNRL-HYEITGGNTRGRFSITSQ--NGRGLITVAQPLDFKQERRYVLTVSATD-- 445
           D DE  NR+  Y I  G+ +  F+I +   +  G+I   +PLD++  ++Y   V ATD  
Sbjct: 284 DPDEPQNRMTKYSILRGDYQDAFTIETNPAHNEGIIKPMKPLDYEYIQQYSFIVEATDPT 343

Query: 446 ------SGGRSDTAMVQINITDANNYAPVFENAPYTASVFED--APIGTTVLVVSATDSD 497
                 S    + A V INITD +   P+F+   Y   + E+   P+  TVL   A D D
Sbjct: 344 IDLRYMSPPAGNRAQVIINITDVDE-PPIFQQPFYHFQLKENQKKPLIGTVL---AMDPD 399

Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD-- 555
              ++ I YS+    S++       QF    + G I   K LDRE    Y LTV A++  
Sbjct: 400 AARHS-IGYSI-RRTSDKG------QFFRVTKKGDIYNEKELDREVYPWYNLTVEAKELD 451

Query: 556 -GGVPSLSDT-TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV-GL 612
             G P+  ++   V I V+D NDN P F +  Y   + E+A+ G  V Q+ A D D+   
Sbjct: 452 STGTPTGKESIVQVHIEVLDENDNAPEFAKP-YQPKVCENAVHGQLVLQISAIDKDITPR 510

Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672
           N +  + L+ ++    +   D  + +       DRE    H L  V  D G P ++ T  
Sbjct: 511 NVKFKFTLNTENNFTLTDNHDNTANITVKYGQFDREHTKVHFLPVVISDNGMPSRTGTST 570

Query: 673 VHIKIEDIND 682
           + + +   N+
Sbjct: 571 LTVAVCKCNE 580



 Score =  160 bits (389), Expect = 4e-37
 Identities = 134/507 (26%), Positives = 230/507 (45%), Gaps = 31/507 (6%)

Query: 86  VQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145
           V  VFR+D  +G +     LDRE ++ Y +     D+ +   + L + ++  + + D ND
Sbjct: 89  VGKVFRVDAETGDVFAIERLDRENISEYHLTAVIVDKDT--GENLETPSSFTIKVHDVND 146

Query: 146 NYPQFSEKTYTVSVDEDISVTDNPV-IAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS 204
           N+P F+ + +  SV E  +V  + + +  + A D  VG ++++ Y I+ G     F+ID+
Sbjct: 147 NWPVFTHRLFNASVPESSAVGTSVISVTAVDADDPTVGDHASVMYQILKGKEY--FAIDN 204

Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDG-GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263
               +++ K+LD E+   Y +V+ A+D  G    S T  +L+ ++D+NDN P F  + + 
Sbjct: 205 SGRIITITKSLDREKQARYEIVVEARDAQGLRGDSGTATVLVTLQDINDNFPFFTQTKYT 264

Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323
             V E+  +G S+  +   D DE  N    Y++   DY     +        G +     
Sbjct: 265 FVVPEDTRVGTSVGSLFVEDPDEPQNRMTKYSILRGDYQDAFTIETNPAHNEGIIKPMKP 324

Query: 324 LDRETQAKYQLLVTATDGG-----DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAED 378
           LD E   +Y  +V ATD         P +                  F    Y  +L E+
Sbjct: 325 LDYEYIQQYSFIVEATDPTIDLRYMSPPAGNRAQVIINITDVDEPPIFQQPFYHFQLKEN 384

Query: 379 EPPGTPVV-TLTATDAD-EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436
           +    P++ T+ A D D   + + Y I   + +G+F   ++  +G I   + LD +    
Sbjct: 385 QK--KPLIGTVLAMDPDAARHSIGYSIRRTSDKGQFFRVTK--KGDIYNEKELDREVYPW 440

Query: 437 YVLTVSATD---SG---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490
           Y LTV A +   +G   G+     V I + D N+ AP F   PY   V E+A  G  VL 
Sbjct: 441 YNLTVEAKELDSTGTPTGKESIVQVHIEVLDENDNAPEFAK-PYQPKVCENAVHGQLVLQ 499

Query: 491 VSATDSDV-GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549
           +SA D D+   N +  ++L++E +     +HD    I  + G        DRE    + L
Sbjct: 500 ISAIDKDITPRNVKFKFTLNTENNFTLTDNHDNTANITVKYGQ------FDREHTKVHFL 553

Query: 550 TVTARDGGVPSLSDTTDVEISVVDVND 576
            V   D G+PS + T+ + ++V   N+
Sbjct: 554 PVVISDNGMPSRTGTSTLTVAVCKCNE 580



 Score =  151 bits (365), Expect = 4e-34
 Identities = 101/287 (35%), Positives = 154/287 (53%), Gaps = 21/287 (7%)

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLT--VTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581
           F ++ +TG +   + LDRE +S Y LT  +  +D G  +L   +   I V DVNDN PVF
Sbjct: 93  FRVDAETGDVFAIERLDRENISEYHLTAVIVDKDTG-ENLETPSSFTIKVHDVNDNWPVF 151

Query: 582 KQQLYTANIMEDALVGTSVSQVGATDAD---VGLNGRIHYELDPKDREEGSFVIDPASGV 638
             +L+ A++ E + VGTSV  V A DAD   VG +  + Y++  K +E   F ID +  +
Sbjct: 152 THRLFNASVPESSAVGTSVISVTAVDADDPTVGDHASVMYQI-LKGKEY--FAIDNSGRI 208

Query: 639 IRTNKALDRESVATHDLKAVAIDG-GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697
           I   K+LDRE  A +++   A D  G    S T  V + ++DIND+ P F     TF + 
Sbjct: 209 ITITKSLDREKQARYEIVVEARDAQGLRGDSGTATVLVTLQDINDNFPFFTQTKYTFVVP 268

Query: 698 ENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757
           E++ +GT++G +   DPDE  N +  YSI  GD  ++F++ET    ++  +  M  LDYE
Sbjct: 269 EDTRVGTSVGSLFVEDPDEPQNRMTKYSILRGDYQDAFTIETNPAHNEGIIKPMKPLDYE 328

Query: 758 SPRKKYELVIRAA---------SPPLWNDVRVEILVTDVNDNAPVMK 795
              ++Y  ++ A          SPP  N  +V I +TDV D  P+ +
Sbjct: 329 Y-IQQYSFIVEATDPTIDLRYMSPPAGNRAQVIINITDV-DEPPIFQ 373



 Score =  128 bits (310), Expect = 2e-27
 Identities = 132/474 (27%), Positives = 207/474 (43%), Gaps = 54/474 (11%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVTA 67
           I V D ND+ PVF  + + ASV E ++ GT+V+++ A D D   +G +A V Y I     
Sbjct: 139 IKVHDVNDNWPVFTHRLFNASVPESSAVGTSVISVTAVDADDPTVGDHASVMYQI----- 193

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
                              ++ F ID     +    SLDREK ARY ++V+A D      
Sbjct: 194 ----------------LKGKEYFAIDNSGRIITITKSLDREKQARYEIVVEARDAQGLRG 237

Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187
           D  S TAT+ V + D NDN+P F++  YT  V ED  V  +  +  +   D D   N   
Sbjct: 238 D--SGTATVLVTLQDINDNFPFFTQTKYTFVVPEDTRVGTS--VGSLFVEDPDEPQNRMT 293

Query: 188 RYAIIGGNTQMQFSIDS----LSGDVSLVKTLDYEQVRSYRLVIRAQDGG------SPSR 237
           +Y+I+ G+ Q  F+I++      G +  +K LDYE ++ Y  ++ A D        SP  
Sbjct: 294 KYSILRGDYQDAFTIETNPAHNEGIIKPMKPLDYEYIQQYSFIVEATDPTIDLRYMSPPA 353

Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297
            N  Q++INI DV D  P F    +   + EN      I  V A D D      + Y++ 
Sbjct: 354 GNRAQVIINITDV-DEPPIFQQPFYHFQLKENQKKPL-IGTVLAMDPD-AARHSIGYSIR 410

Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD---GGDPPRSATATXXX 354
                G     +T   + G +Y   +LDRE    Y L V A +    G P    +     
Sbjct: 411 RTSDKGQF-FRVT---KKGDIYNEKELDREVYPWYNLTVEAKELDSTGTPTGKESIVQVH 466

Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR-LHYEITGGNTRGRFS 413
                           Y+ ++ E+   G  V+ ++A D D   R + ++ T  NT   F+
Sbjct: 467 IEVLDENDNAPEFAKPYQPKVCENAVHGQLVLQISAIDKDITPRNVKFKFT-LNTENNFT 525

Query: 414 IT-SQNGRGLITVAQ-PLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDAN 463
           +T + +    ITV     D +  + + L V  +D+G   R+ T+ + + +   N
Sbjct: 526 LTDNHDNTANITVKYGQFDREHTKVHFLPVVISDNGMPSRTGTSTLTVAVCKCN 579



 Score =  119 bits (286), Expect = 1e-24
 Identities = 124/442 (28%), Positives = 186/442 (42%), Gaps = 36/442 (8%)

Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
           +Y G V     +D  +G V+   +LDRE  ++Y L     D        T +        
Sbjct: 87  EYVGKV---FRVDAETGDVFAIERLDRENISEYHLTAVIVDKDTGENLETPSSFTIKVHD 143

Query: 360 XXXXX-XFMPGQYEVELAEDEPPGTPVVTLTATDADEDN-RLHYEITGGNTRGRFSITSQ 417
                  F    +   + E    GT V+++TA DAD+     H  +     +G+      
Sbjct: 144 VNDNWPVFTHRLFNASVPESSAVGTSVISVTAVDADDPTVGDHASVMYQILKGKEYFAID 203

Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGG-RSD--TAMVQINITDANNYAPVFENAPY 474
           N   +IT+ + LD +++ RY + V A D+ G R D  TA V + + D N+  P F    Y
Sbjct: 204 NSGRIITITKSLDREKQARYEIVVEARDAQGLRGDSGTATVLVTLQDINDNFPFFTQTKY 263

Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP--QTGA 532
           T  V ED  +GT+V  +   D D   N    YS+      +A          NP    G 
Sbjct: 264 TFVVPEDTRVGTSVGSLFVEDPDEPQNRMTKYSILRGDYQDAFT-----IETNPAHNEGI 318

Query: 533 ITTNKLLDRETMSGYLLTVTARDGGV------PSLSDTTDVEISVVDVNDNEPVFKQQLY 586
           I   K LD E +  Y   V A D  +      P   +   V I++ DV D  P+F+Q  Y
Sbjct: 319 IKPMKPLDYEYIQQYSFIVEATDPTIDLRYMSPPAGNRAQVIINITDV-DEPPIFQQPFY 377

Query: 587 TANIMEDA---LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK 643
              + E+    L+GT    V A D D   +  I Y +  +  ++G F      G I   K
Sbjct: 378 HFQLKENQKKPLIGT----VLAMDPDAARHS-IGYSIR-RTSDKGQFFRVTKKGDIYNEK 431

Query: 644 ALDRESVATHDL--KAVAIDG-GTPPQSSTVI-VHIKIEDINDSPPVFESDCLTFYISEN 699
            LDRE    ++L  +A  +D  GTP    +++ VHI++ D ND+ P F        + EN
Sbjct: 432 ELDREVYPWYNLTVEAKELDSTGTPTGKESIVQVHIEVLDENDNAPEFAKPYQP-KVCEN 490

Query: 700 SPIGTTIGEIRAHDPDEGPNAV 721
           +  G  + +I A D D  P  V
Sbjct: 491 AVHGQLVLQISAIDKDITPRNV 512


>UniRef50_UPI0000F1E792 Cluster: PREDICTED: hypothetical protein;
           n=2; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 826

 Score =  163 bits (395), Expect = 8e-38
 Identities = 176/630 (27%), Positives = 282/630 (44%), Gaps = 70/630 (11%)

Query: 96  SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155
           SG L     LDREK   Y++ V  T          + + T+ V +ID NDN P F E++ 
Sbjct: 69  SGFLYALKPLDREKQPSYSLQVSFTKSMH------TQSFTVEVCVIDKNDNVPVFLEESM 122

Query: 156 TVSVDEDISVTDNPVIAKIKATDADVG--ANSAIRYAIIGGNTQM----QFSIDSLSGDV 209
             SV   + +       +++A D D    A++ +R++++    ++     FSIDS++G+V
Sbjct: 123 RGSVQ--LGLLKGIPFMQVEALDRDDRNTAHADLRFSLLDQIPRIPASHMFSIDSITGEV 180

Query: 210 SLVK----TLDYEQVRSYRLVIRAQD--GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263
           SL +    TLD E    Y+L +  QD  G + +  +T  +L+   +V  NA   + S   
Sbjct: 181 SLTEDGASTLDPEMCGRYKLSVMVQDMAGKANAFFSTGTVLV---EVTGNA---WASPDP 234

Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323
             + EN+P  Y I   Q   +   V   L     +  +T N         R G +Y +  
Sbjct: 235 VRLQENLPGPYPIPISQVKWSGSPVEYSLEGEFPEMLFTIN---------REGIIYLNAP 285

Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383
           LDRETQ ++ + +          +                  F   QY   + E    GT
Sbjct: 286 LDRETQDQFHIDIVVERPDGREIAKPVELRVMVGDANDNRPTFPQMQYHTVVKELATKGT 345

Query: 384 PVVTLTATDADE---DN-RLHYEITGG---NTRGRFSITSQNGRGLITVAQPLDFKQERR 436
            ++T+ A D D+   DN R+ Y + G      R  F +   +G  +ITV          +
Sbjct: 346 EILTVQAADNDDPKTDNVRIFYRLVGQMPETPRNLFRVDRDSG--VITVQADSMEGTAPQ 403

Query: 437 YVLTVSATDSGGRSDT-------AMVQINITDANNYAPVFENAPYTA-SVFEDAPIGTTV 488
           Y LT++A D+ GR +T         V + + D NN  P+F +  Y    + ED+ +GTTV
Sbjct: 404 YTLTITAEDAKGRHNTDQWLNSSCTVIVKVLDENNNPPIFSHLEYGPFHLAEDSSVGTTV 463

Query: 489 LVVSATDSDV--GINAQITYSLSSEISNEAVAH-HDQQFVINPQTGAITTNKLLDRETMS 545
            VVSA D+D   G + Q+ Y L S    E     +D+Q        A+  +K+LD E  +
Sbjct: 464 TVVSAWDADEWGGDSWQVDYRLESGNEEEVFTLLNDRQ----TNEAALILDKVLDFEREN 519

Query: 546 GYLLTVTARDG-----GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600
            Y+L ++A++      G    + T  V I + D+N+  PV  Q  Y   + E    G  +
Sbjct: 520 EYILVLSAQNPVALVRGRYGPASTATVTIFIDDINEG-PVLSQSHYEVTVREGEEPGRVI 578

Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660
           + +   D D   +  I Y L  +   +  F I   SG ++T +ALDRE   T+ ++ VA 
Sbjct: 579 ATIRGYDPD---SHPIRYSL--RGDTKRYFSIGKYSGELKTVQALDREENHTYTMEVVAE 633

Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESD 690
           DG     S++ +V + I D+ND+ PV   D
Sbjct: 634 DGRNSSLSASTLVTVHILDVNDNSPVLVGD 663



 Score =  136 bits (330), Expect = 6e-30
 Identities = 170/631 (26%), Positives = 272/631 (43%), Gaps = 55/631 (8%)

Query: 192 IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251
           + G+ +  F ++S  G +  +K LD E+  SY L +        ++S T ++ +   D N
Sbjct: 57  VNGDDEGIFGVES--GFLYALKPLDREKQPSYSLQVSFTKS-MHTQSFTVEVCVI--DKN 111

Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG--VNAELTYTMTDKDYTGNVDLPI 309
           DN P F     + SV   +  G   ++V+A D D+    +A+L +++ D+          
Sbjct: 112 DNVPVFLEESMRGSVQLGLLKGIPFMQVEALDRDDRNTAHADLRFSLLDQIPRIPASHMF 171

Query: 310 TIDPRSGWVYTS----GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365
           +ID  +G V  +      LD E   +Y+L V   D      +  +T              
Sbjct: 172 SIDSITGEVSLTEDGASTLDPEMCGRYKLSVMVQDMAGKANAFFSTGTVLVEVTGNAWAS 231

Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV 425
             P    V L E+ P   P+       +     + Y + G      F+I   N  G+I +
Sbjct: 232 PDP----VRLQENLPGPYPIPISQVKWSGSP--VEYSLEGEFPEMLFTI---NREGIIYL 282

Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAP 483
             PLD + + ++ + +      GR     V++ +   DAN+  P F    Y   V E A 
Sbjct: 283 NAPLDRETQDQFHIDIVVERPDGREIAKPVELRVMVGDANDNRPTFPQMQYHTVVKELAT 342

Query: 484 IGTTVLVVSATDSD--VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
            GT +L V A D+D     N +I Y L  ++           F ++  +G IT       
Sbjct: 343 KGTEILTVQAADNDDPKTDNVRIFYRLVGQMPETP----RNLFRVDRDSGVITVQADSME 398

Query: 542 ETMSGYLLTVTARDG-GVPS----LSDTTDVEISVVDVNDNEPVFKQQLYTA-NIMEDAL 595
            T   Y LT+TA D  G  +    L+ +  V + V+D N+N P+F    Y   ++ ED+ 
Sbjct: 399 GTAPQYTLTITAEDAKGRHNTDQWLNSSCTVIVKVLDENNNPPIFSHLEYGPFHLAEDSS 458

Query: 596 VGTSVSQVGATDADV--GLNGRIHYELDPKDREEGSFVIDPAS---GVIRTNKALD--RE 648
           VGT+V+ V A DAD   G + ++ Y L+  + EE   +++        +  +K LD  RE
Sbjct: 459 VGTTVTVVSAWDADEWGGDSWQVDYRLESGNEEEVFTLLNDRQTNEAALILDKVLDFERE 518

Query: 649 SVATHDLKA---VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
           +     L A   VA+  G    +ST  V I I+DIN+ P + +S      + E    G  
Sbjct: 519 NEYILVLSAQNPVALVRGRYGPASTATVTIFIDDINEGPVLSQSH-YEVTVREGEEPGRV 577

Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYE 764
           I  IR +DPD  P   + YS++G D    FS+    G    EL T+  LD E       E
Sbjct: 578 IATIRGYDPDSHP---IRYSLRG-DTKRYFSI----GKYSGELKTVQALDREENHTYTME 629

Query: 765 LVIR-AASPPLWNDVRVEILVTDVNDNAPVM 794
           +V     +  L     V + + DVNDN+PV+
Sbjct: 630 VVAEDGRNSSLSASTLVTVHILDVNDNSPVL 660



 Score =  132 bits (319), Expect = 1e-28
 Identities = 153/592 (25%), Positives = 243/592 (41%), Gaps = 57/592 (9%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ V+D ND+ PVF  +    SV+ G   G   + ++A D+D    A  +    L+  D 
Sbjct: 104 EVCVIDKNDNVPVFLEESMRGSVQLGLLKGIPFMQVEALDRDDRNTAHADLRFSLL--DQ 161

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
           +    A           +     DG S       +LD E   RY + V   D A   ++ 
Sbjct: 162 IPRIPASHMFSIDSITGEVSLTEDGAS-------TLDPEMCGRYKLSVMVQDMAGK-ANA 213

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             ST T+ V +  +    P        V + E++       I+++K       + S + Y
Sbjct: 214 FFSTGTVLVEVTGNAWASPD------PVRLQENLPGPYPIPISQVK------WSGSPVEY 261

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
           ++ G   +M F+I+   G + L   LD E    + + I  +       +   +L + + D
Sbjct: 262 SLEGEFPEMLFTINR-EGIIYLNAPLDRETQDQFHIDIVVERPDGREIAKPVELRVMVGD 320

Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV--NAELTYTMTDKDYTGNVDL 307
            NDN P F    +   V E    G  I+ VQA D D+    N  + Y +  +      +L
Sbjct: 321 ANDNRPTFPQMQYHTVVKELATKGTEILTVQAADNDDPKTDNVRIFYRLVGQMPETPRNL 380

Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATD-----GGDPPRSATATXXXXXXXXXXX 362
              +D  SG +         T  +Y L +TA D       D   +++ T           
Sbjct: 381 -FRVDRDSGVITVQADSMEGTAPQYTLTITAEDAKGRHNTDQWLNSSCTVIVKVLDENNN 439

Query: 363 XXXFMPGQY-EVELAEDEPPGTPVVTLTATDADE---DN-RLHYEITGGNTRGRFSITS- 416
              F   +Y    LAED   GT V  ++A DADE   D+ ++ Y +  GN    F++ + 
Sbjct: 440 PPIFSHLEYGPFHLAEDSSVGTTVTVVSAWDADEWGGDSWQVDYRLESGNEEEVFTLLND 499

Query: 417 -QNGRGLITVAQPLDFKQERRYVLTVSATD-------SGGRSDTAMVQINITDANNYAPV 468
            Q     + + + LDF++E  Y+L +SA +         G + TA V I I D N   PV
Sbjct: 500 RQTNEAALILDKVLDFERENEYILVLSAQNPVALVRGRYGPASTATVTIFIDDINE-GPV 558

Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528
              + Y  +V E    G  +  +   D D   +  I YSL  +          + F I  
Sbjct: 559 LSQSHYEVTVREGEEPGRVIATIRGYDPD---SHPIRYSLRGDTK--------RYFSIGK 607

Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580
            +G + T + LDRE    Y + V A DG   SLS +T V + ++DVNDN PV
Sbjct: 608 YSGELKTVQALDREENHTYTMEVVAEDGRNSSLSASTLVTVHILDVNDNSPV 659



 Score =  117 bits (281), Expect = 5e-24
 Identities = 155/627 (24%), Positives = 251/627 (40%), Gaps = 60/627 (9%)

Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355
           +T  D T N D        SG++Y    LDRE Q  Y L V+ T       + + T    
Sbjct: 50  LTYSDLTVNGDDEGIFGVESGFLYALKPLDREKQPSYSLQVSFTKS---MHTQSFTVEVC 106

Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG--------N 407
                     F+       +      G P + + A D D+ N  H ++            
Sbjct: 107 VIDKNDNVPVFLEESMRGSVQLGLLKGIPFMQVEALDRDDRNTAHADLRFSLLDQIPRIP 166

Query: 408 TRGRFSITSQNGRGLITV--AQPLDFKQERRYVLTVSATDSGGRSD----TAMVQINITD 461
               FSI S  G   +T   A  LD +   RY L+V   D  G+++    T  V + +T 
Sbjct: 167 ASHMFSIDSITGEVSLTEDGASTLDPEMCGRYKLSVMVQDMAGKANAFFSTGTVLVEVT- 225

Query: 462 ANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521
            N +A     +P    + E+ P G   + +S         + + YSL  E         +
Sbjct: 226 GNAWA-----SPDPVRLQENLP-GPYPIPISQVKWS---GSPVEYSLEGEFP-------E 269

Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581
             F IN + G I  N  LDRET   + + +         ++   ++ + V D NDN P F
Sbjct: 270 MLFTINRE-GIIYLNAPLDRETQDQFHIDIVVERPDGREIAKPVELRVMVGDANDNRPTF 328

Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGL--NGRIHYEL--DPKDREEGSFVIDPASG 637
            Q  Y   + E A  GT +  V A D D     N RI Y L     +     F +D  SG
Sbjct: 329 PQMQYHTVVKELATKGTEILTVQAADNDDPKTDNVRIFYRLVGQMPETPRNLFRVDRDSG 388

Query: 638 VIRTNKALDRESVATHDLKAVAIDGGTPPQS-----STVIVHIKIEDINDSPPVFES-DC 691
           VI         +   + L   A D      +     S+  V +K+ D N++PP+F   + 
Sbjct: 389 VITVQADSMEGTAPQYTLTITAEDAKGRHNTDQWLNSSCTVIVKVLDENNNPPIFSHLEY 448

Query: 692 LTFYISENSPIGTTIGEIRAHDPDE--GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV 749
             F+++E+S +GTT+  + A D DE  G +  V Y ++ G++   F+L   + +++A L+
Sbjct: 449 GPFHLAEDSSVGTTVTVVSAWDADEWGGDSWQVDYRLESGNEEEVFTLLNDRQTNEAALI 508

Query: 750 TMVDLDYESPRKKYELVIRAASPPLW--------NDVRVEILVTDVNDNAPVMKDFQIIF 801
               LD+E    +Y LV+ A +P           +   V I + D+N+  PV+       
Sbjct: 509 LDKVLDFER-ENEYILVLSAQNPVALVRGRYGPASTATVTIFIDDINE-GPVLSQSHYEV 566

Query: 802 NNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPK 861
              +   P      +  YD D +  ++Y  L G+      + + +G +     L+     
Sbjct: 567 TVREGEEPGRVIATIRGYDPD-SHPIRYS-LRGDTKRYFSIGKYSGELKTVQALDREENH 624

Query: 862 LATMEVSVTDGVN-EIKAMMQLSVRLI 887
             TMEV   DG N  + A   ++V ++
Sbjct: 625 TYTMEVVAEDGRNSSLSASTLVTVHIL 651



 Score =  108 bits (260), Expect = 2e-21
 Identities = 101/357 (28%), Positives = 166/357 (46%), Gaps = 39/357 (10%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           +  ++ V D ND+ P F   QY   V+E A+ GT +LT++A D D  K   V     LV 
Sbjct: 312 VELRVMVGDANDNRPTFPQMQYHTVVKELATKGTEILTVQAADNDDPKTDNVRIFYRLVG 371

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD-QASP 125
                P              +++FR+D  SG +  +A        +YT+ + A D +   
Sbjct: 372 QMPETP--------------RNLFRVDRDSGVITVQADSMEGTAPQYTLTITAEDAKGRH 417

Query: 126 VSDR-LSSTATIHVNIIDDNDNYPQFSEKTY-TVSVDEDISVTDNPVIAKIKATDADV-- 181
            +D+ L+S+ T+ V ++D+N+N P FS   Y    + ED SV     +  + A DAD   
Sbjct: 418 NTDQWLNSSCTVIVKVLDENNNPPIFSHLEYGPFHLAEDSSV--GTTVTVVSAWDADEWG 475

Query: 182 GANSAIRYAIIGGNTQMQFSI--DSLSGDVSLV--KTLDYEQVRSYRLVIRAQD-----G 232
           G +  + Y +  GN +  F++  D  + + +L+  K LD+E+   Y LV+ AQ+      
Sbjct: 476 GDSWQVDYRLESGNEEEVFTLLNDRQTNEAALILDKVLDFERENEYILVLSAQNPVALVR 535

Query: 233 GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292
           G    ++T  + I I D+N+  P    S ++ +V E    G  I  ++ YD D   +  +
Sbjct: 536 GRYGPASTATVTIFIDDINE-GPVLSQSHYEVTVREGEEPGRVIATIRGYDPD---SHPI 591

Query: 293 TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT 349
            Y++      G+     +I   SG + T   LDRE    Y + V A DG +   SA+
Sbjct: 592 RYSL-----RGDTKRYFSIGKYSGELKTVQALDREENHTYTMEVVAEDGRNSSLSAS 643


>UniRef50_Q0YH47 Cluster: Cadherin; n=1; Geobacter sp. FRC-32|Rep:
           Cadherin - Geobacter sp. FRC-32
          Length = 1129

 Score =  161 bits (392), Expect = 2e-37
 Identities = 134/439 (30%), Positives = 203/439 (46%), Gaps = 42/439 (9%)

Query: 366 FMP--GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423
           FMP  G Y V LAE+   GTPV  ++ATDAD D  + Y I  GN  G F+I + +G   +
Sbjct: 173 FMPNLGNYAVTLAENSAKGTPVGKVSATDADGDT-ITYTIIAGNDNGAFAIDAASGAITV 231

Query: 424 TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
             A  LDF+  R + LTV A+D G  SDT  V IN+ D N+ APV  +   + +V E+AP
Sbjct: 232 ADASKLDFEATREFTLTVQASD-GRLSDTGTVTINLVDRNDNAPVITSGS-SGTVAENAP 289

Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
             T +   +A D+D      ITYSL                 I+P +G +T N   D ET
Sbjct: 290 TDTVIYQAAARDADT--ETTITYSLKP-------GEDTSLLTIDPGSGTVTLNNSADFET 340

Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
            + Y  TV A DG     S    V +SV+++NDN P+        ++ E+A + T + Q 
Sbjct: 341 KTSYTFTVIAGDG---VNSSEQAVTVSVLNLNDNSPILTSGA-GGSVAENAPISTVIYQA 396

Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
            A+DAD   +    Y L P   +     +D A+G +      D ES   +       DG 
Sbjct: 397 AASDADG--DASFTYSLKP-GGDADLLHVDSATGAVTLRSLADFESKPGYSFTVAVSDGI 453

Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESD---CLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
              +     + + + D+N++P +  +         +SEN    TT   + A D D G + 
Sbjct: 454 HTTEQE---IAVSVTDVNEAPVITSNGGEATAAISVSENQAAVTT---VTATDVDAGDSR 507

Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP-----RKKYELVIRAASPPLW 775
              +SI GG D+  F+++   G+    L  +   D E P        Y++ +        
Sbjct: 508 T--FSITGGADAALFAIDAETGA----LTFLAAPDREKPADVDHNNIYDVQVAVTDRGGL 561

Query: 776 NDVR-VEILVTDVNDNAPV 793
           +DV+ + + VTDV ++  V
Sbjct: 562 SDVQDLAVSVTDVREHVVV 580



 Score =  140 bits (340), Expect = 4e-31
 Identities = 128/431 (29%), Positives = 192/431 (44%), Gaps = 41/431 (9%)

Query: 155 YTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSL--V 212
           Y V++ E+ S    PV  K+ ATDAD      I Y II GN    F+ID+ SG +++   
Sbjct: 180 YAVTLAEN-SAKGTPV-GKVSATDAD---GDTITYTIIAGNDNGAFAIDAASGAITVADA 234

Query: 213 KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI 272
             LD+E  R + L ++A DG     S+T  + IN+ D NDNAP   TS    +V+EN P 
Sbjct: 235 SKLDFEATREFTLTVQASDG---RLSDTGTVTINLVDRNDNAP-VITSGSSGTVAENAPT 290

Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332
              I +  A DAD      +TY++   + T      +TIDP SG V  +   D ET+  Y
Sbjct: 291 DTVIYQAAARDAD--TETTITYSLKPGEDTS----LLTIDPGSGTVTLNNSADFETKTSY 344

Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392
              V A DG +    A                    G     +AE+ P  T +    A+D
Sbjct: 345 TFTVIAGDGVNSSEQAVTVSVLNLNDNSPILTSGAGG----SVAENAPISTVIYQAAASD 400

Query: 393 ADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT 452
           AD D    Y +  G       + S    G +T+    DF+ +  Y  TV+ +D G  +  
Sbjct: 401 ADGDASFTYSLKPGGDADLLHVDS--ATGAVTLRSLADFESKPGYSFTVAVSD-GIHTTE 457

Query: 453 AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512
             + +++TD N    +  N     +    +     V  V+ATD D G +   T+S++   
Sbjct: 458 QEIAVSVTDVNEAPVITSNGGEATAAISVSENQAAVTTVTATDVDAGDSR--TFSITGG- 514

Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG------YLLTVTARDGGVPSLSDTTD 566
           ++ A+      F I+ +TGA+T     DRE  +       Y + V   D G   LSD  D
Sbjct: 515 ADAAL------FAIDAETGALTFLAAPDREKPADVDHNNIYDVQVAVTDRG--GLSDVQD 566

Query: 567 VEISVVDVNDN 577
           + +SV DV ++
Sbjct: 567 LAVSVTDVREH 577



 Score =  133 bits (321), Expect = 8e-29
 Identities = 114/385 (29%), Positives = 177/385 (45%), Gaps = 30/385 (7%)

Query: 90  FRIDGRSGALLTR--ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
           F ID  SGA+     + LD E    +T+ V+A+D       RLS T T+ +N++D NDN 
Sbjct: 220 FAIDAASGAITVADASKLDFEATREFTLTVQASD------GRLSDTGTVTINLVDRNDNA 273

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
           P  +  + + +V E+ + TD  VI +  A DAD    + I Y++  G      +ID  SG
Sbjct: 274 PVITSGS-SGTVAEN-APTDT-VIYQAAARDADT--ETTITYSLKPGEDTSLLTIDPGSG 328

Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
            V+L  + D+E   SY   + A DG + S    T   +++ ++NDN+P   TS    SV+
Sbjct: 329 TVTLNNSADFETKTSYTFTVIAGDGVNSSEQAVT---VSVLNLNDNSP-ILTSGAGGSVA 384

Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
           EN PI   I +  A DAD   +A  TY++      G+ DL + +D  +G V      D E
Sbjct: 385 ENAPISTVIYQAAASDADG--DASFTYSLKP---GGDADL-LHVDSATGAVTLRSLADFE 438

Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387
           ++  Y   V  +DG        A                      + ++E++     V T
Sbjct: 439 SKPGYSFTVAVSDGIHTTEQEIAVSVTDVNEAPVITSNGGEATAAISVSENQ---AAVTT 495

Query: 388 LTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA----QPLDFKQERRYVLTVSA 443
           +TATD D  +   + ITGG     F+I ++ G      A    +P D      Y + V+ 
Sbjct: 496 VTATDVDAGDSRTFSITGGADAALFAIDAETGALTFLAAPDREKPADVDHNNIYDVQVAV 555

Query: 444 TDSGGRSDTAMVQINITDANNYAPV 468
           TD GG SD   + +++TD   +  V
Sbjct: 556 TDRGGLSDVQDLAVSVTDVREHVVV 580



 Score =  125 bits (301), Expect = 2e-26
 Identities = 126/443 (28%), Positives = 204/443 (46%), Gaps = 43/443 (9%)

Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523
           N+ P   N  Y  ++ E++  GT V  VSATD+D      ITY++ +   N A       
Sbjct: 172 NFMPNLGN--YAVTLAENSAKGTPVGKVSATDAD---GDTITYTIIAGNDNGA------- 219

Query: 524 FVINPQTGAITTNKL--LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581
           F I+  +GAIT      LD E    + LTV A DG    LSDT  V I++VD NDN PV 
Sbjct: 220 FAIDAASGAITVADASKLDFEATREFTLTVQASDG---RLSDTGTVTINLVDRNDNAPVI 276

Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641
                +  + E+A   T + Q  A DAD      I Y L P + +     IDP SG +  
Sbjct: 277 TSGS-SGTVAENAPTDTVIYQAAARDADTETT--ITYSLKPGE-DTSLLTIDPGSGTVTL 332

Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701
           N + D E+  ++    +A DG     SS   V + + ++ND+ P+  S      ++EN+P
Sbjct: 333 NNSADFETKTSYTFTVIAGDG---VNSSEQAVTVSVLNLNDNSPILTSGA-GGSVAENAP 388

Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDL-DYESPR 760
           I T I +  A D D   +A   YS+K G D++   +++  G+     VT+  L D+ES +
Sbjct: 389 ISTVIYQAAASDADG--DASFTYSLKPGGDADLLHVDSATGA-----VTLRSLADFES-K 440

Query: 761 KKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD 820
             Y   +  +      +  + + VTDVN+   +  +                   V A D
Sbjct: 441 PGYSFTVAVSDGIHTTEQEIAVSVTDVNEAPVITSNGGEATAAISVSENQAAVTTVTATD 500

Query: 821 ADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVP------KLATMEVSVTD--G 872
            D  D   + I  G +A L  ++  TG++T     +   P       +  ++V+VTD  G
Sbjct: 501 VDAGDSRTFSITGGADAALFAIDAETGALTFLAAPDREKPADVDHNNIYDVQVAVTDRGG 560

Query: 873 VNEIKAMMQLSVRLITEEMLLNS 895
           +++++  + +SV  + E +++ +
Sbjct: 561 LSDVQD-LAVSVTDVREHVVVEA 582


>UniRef50_Q12864 Cluster: Cadherin-17 precursor; n=25;
           Tetrapoda|Rep: Cadherin-17 precursor - Homo sapiens
           (Human)
          Length = 832

 Score =  161 bits (392), Expect = 2e-37
 Identities = 204/724 (28%), Positives = 318/724 (43%), Gaps = 74/724 (10%)

Query: 88  DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
           ++F I+ R G L    +LDRE  + + + V A D    +   +     I + + D NDN 
Sbjct: 68  NIFVIE-REGLLYYNRALDRETRSTHNLQVAALDANGII---VEGPVPITIKVKDINDNR 123

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA--NSAIRYAIIGG----NTQMQFS 201
           P F +  Y  SV ++ S    P +  + ATD D  A  N  + Y I+      N  M F 
Sbjct: 124 PTFLQSKYEGSVRQN-SRPGKPFL-YVNATDLDDPATPNGQLYYQIVIQLPMINNVMYFQ 181

Query: 202 IDSLSGDVSLVK----TLDYEQVRSYRLVIRAQDGGSPSR---SNTTQLLINIRDVNDNA 254
           I++ +G +SL +     L+  +  SY LVI  +D G  S    S+TT + I + +    A
Sbjct: 182 INNKTGAISLTREGSQELNPAKNPSYNLVISVKDMGGQSENSFSDTTSVDIIVTENIWKA 241

Query: 255 PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR 314
           P+    +  E+ ++  PI  + VR      D G      Y++ DK+       P +ID +
Sbjct: 242 PKPVEMV--ENSTDPHPIKITQVRWN----DPGAQ----YSLVDKEKLPR--FPFSID-Q 288

Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374
            G +Y +  LDRE +  Y     A D    P S                          E
Sbjct: 289 EGDIYVTQPLDREEKDAYVFYAVAKDEYGKPLSYPLEIHVKVKDINDNPPTCPSPVTVFE 348

Query: 375 LAEDEPPGTPVVTLTATDADEDNR----LHYEITGGNTR----GRFSITSQNGRGLITVA 426
           + E+E  G  + TLTA D DE+N     L+Y I     +    G F I  Q   G++ +A
Sbjct: 349 VQENERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDGLFLI--QTYAGMLQLA 406

Query: 427 -QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPY-TASVFEDAPI 484
            Q L  +   +Y LT+  +D   ++    VQIN+ D N+  P+FE + Y   ++ ED  I
Sbjct: 407 KQSLKKQDTPQYNLTIEVSDKDFKT-LCFVQINVIDINDQIPIFEKSDYGNLTLAEDTNI 465

Query: 485 GTTVLVVSATDSDVGI--NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542
           G+T+L + ATD+D     +++I Y +   I  ++          +  TG +   K LD E
Sbjct: 466 GSTILTIQATDADEPFTGSSKILYHI---IKGDSEGRLGVDTDPHTNTGYVIIKKPLDFE 522

Query: 543 TMSGYLLTVTARD------GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596
           T +   +   A +      G   + S      + V DVN+  P F Q ++ A + ED  +
Sbjct: 523 TAAVSNIVFKAENPEPLVFGVKYNASSFAKFTLIVTDVNE-APQFSQHVFQAKVSEDVAI 581

Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
           GT V  V A D + GL+  I Y L    R  G   ID  +G I +   LDRE+ + + ++
Sbjct: 582 GTKVGNVTAKDPE-GLD--ISYSLRGDTR--GWLKIDHVTGEIFSVAPLDREAGSPYRVQ 636

Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL-TFYISENSPIGTTIGEIRAHDPD 715
            VA + G    SS    H+ + D+ND+PP    D    F+    S  G+ I E    D  
Sbjct: 637 VVATEVGGSSLSSVSEFHLILMDVNDNPPRLAKDYTGLFFCHPLSAPGSLIFEATDDDQH 696

Query: 716 --EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR---AA 770
              GP+    +S+  G   N + +    G+  A L T    D+E   ++Y ++IR     
Sbjct: 697 LFRGPHFT--FSLGSGSLQNDWEVSKINGT-HARLSTR-HTDFE--EREYVVLIRINDGG 750

Query: 771 SPPL 774
            PPL
Sbjct: 751 RPPL 754



 Score =  134 bits (325), Expect = 3e-29
 Identities = 178/693 (25%), Positives = 289/693 (41%), Gaps = 80/693 (11%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD--IGKNAEVEYTIELVTAD 68
           I V D ND+ P F   +YE SVR+ +  G   L + ATD D     N ++ Y I ++   
Sbjct: 114 IKVKDINDNRPTFLQSKYEGSVRQNSRPGKPFLYVNATDLDDPATPNGQLYYQI-VIQLP 172

Query: 69  TLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTR---ASLDREKVARYTVLVKATDQAS 124
            +N              V   F+I+ ++GA+ LTR     L+  K   Y +++   D   
Sbjct: 173 MIN-------------NVM-YFQINNKTGAISLTREGSQELNPAKNPSYNLVISVKDMGG 218

Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV-IAKIKATDADVGA 183
              +  S T ++ + + ++    P+       V + E+ S   +P+ I +++  D   GA
Sbjct: 219 QSENSFSDTTSVDIIVTENIWKAPK------PVEMVEN-STDPHPIKITQVRWNDP--GA 269

Query: 184 NSAIRYAIIGGN--TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
               +Y+++      +  FSID   GD+ + + LD E+  +Y     A+D      S   
Sbjct: 270 ----QYSLVDKEKLPRFPFSIDQ-EGDIYVTQPLDREEKDAYVFYAVAKDEYGKPLSYPL 324

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE--GVNAELTYTMTDK 299
           ++ + ++D+NDN P   + +    V EN  +G SI  + A+D DE    N+ L Y + ++
Sbjct: 325 EIHVKVKDINDNPPTCPSPVTVFEVQENERLGNSIGTLTAHDRDEENTANSFLNYRIVEQ 384

Query: 300 DYTGNVDLPITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358
                +D    I   +G +  + Q L ++   +Y L +  +   D               
Sbjct: 385 TPKLPMDGLFLIQTYAGMLQLAKQSLKKQDTPQYNLTIEVS---DKDFKTLCFVQINVID 441

Query: 359 XXXXXXXFMPGQY-EVELAEDEPPGTPVVTLTATDADE----DNRLHYEITGGNTRGRFS 413
                  F    Y  + LAED   G+ ++T+ ATDADE     +++ Y I  G++ GR  
Sbjct: 442 INDQIPIFEKSDYGNLTLAEDTNIGSTILTIQATDADEPFTGSSKILYHIIKGDSEGRLG 501

Query: 414 ITS--QNGRGLITVAQPLDFKQERRYVLTVSATD--------SGGRSDTAMVQINITDAN 463
           + +      G + + +PLDF+      +   A +            S  A   + +TD N
Sbjct: 502 VDTDPHTNTGYVIIKKPLDFETAAVSNIVFKAENPEPLVFGVKYNASSFAKFTLIVTDVN 561

Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523
             AP F    + A V ED  IGT V  V+A D + G++  I+YSL  +        H   
Sbjct: 562 E-APQFSQHVFQAKVSEDVAIGTKVGNVTAKDPE-GLD--ISYSLRGDTRGWLKIDH--- 614

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583
                 TG I +   LDRE  S Y + V A + G  SLS  ++  + ++DVNDN P   +
Sbjct: 615 -----VTGEIFSVAPLDREAGSPYRVQVVATEVGGSSLSSVSEFHLILMDVNDNPPRLAK 669

Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID-PASGVIRTN 642
             YT       L         ATD D  L    H+         GS   D   S +  T+
Sbjct: 670 D-YTGLFFCHPLSAPGSLIFEATDDDQHLFRGPHFTF---SLGSGSLQNDWEVSKINGTH 725

Query: 643 KALDRESVATHDLKAVAI----DGGTPPQSSTV 671
             L        + + V +    DGG PP    V
Sbjct: 726 ARLSTRHTDFEEREYVVLIRINDGGRPPLEGIV 758



 Score =  131 bits (317), Expect = 2e-28
 Identities = 158/636 (24%), Positives = 269/636 (42%), Gaps = 52/636 (8%)

Query: 194 GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDN 253
           G T   F I+   G +   + LD E   ++ L + A D           + I ++D+NDN
Sbjct: 64  GETDNIFVIER-EGLLYYNRALDRETRSTHNLQVAALDANGIIVEGPVPITIKVKDINDN 122

Query: 254 APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV--NAELTYTMTDKDYTGNVDLPITI 311
            P F  S ++ SV +N   G   + V A D D+    N +L Y +  +    N  +   I
Sbjct: 123 RPTFLQSKYEGSVRQNSRPGKPFLYVNATDLDDPATPNGQLYYQIVIQLPMINNVMYFQI 182

Query: 312 DPRSGWVYT----SGQLDRETQAKYQLLVTATD-GGDPPRSATATXXXXXXXXXXXXXXF 366
           + ++G +      S +L+      Y L+++  D GG    S + T               
Sbjct: 183 NNKTGAISLTREGSQELNPAKNPSYNLVISVKDMGGQSENSFSDTTSVDIIVTENIWKAP 242

Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426
            P    VE+ E+     P + +T    + D    Y +       RF   S +  G I V 
Sbjct: 243 KP----VEMVENSTDPHP-IKITQVRWN-DPGAQYSLVDKEKLPRFPF-SIDQEGDIYVT 295

Query: 427 QPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
           QPLD +++  YV    A D  G+  S    + + + D N+  P   +      V E+  +
Sbjct: 296 QPLDREEKDAYVFYAVAKDEYGKPLSYPLEIHVKVKDINDNPPTCPSPVTVFEVQENERL 355

Query: 485 GTTVLVVSATDSDV--GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK-LLDR 541
           G ++  ++A D D     N+ + Y +  +     +   D  F+I    G +   K  L +
Sbjct: 356 GNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPM---DGLFLIQTYAGMLQLAKQSLKK 412

Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY-TANIMEDALVGTSV 600
           +    Y LT+   D    +L     V+I+V+D+ND  P+F++  Y    + ED  +G+++
Sbjct: 413 QDTPQYNLTIEVSDKDFKTL---CFVQINVIDINDQIPIFEKSDYGNLTLAEDTNIGSTI 469

Query: 601 SQVGATDADVGLNG--RIHYELDPKDREEGSFVID----PASGVIRTNKALDRESVATHD 654
             + ATDAD    G  +I Y +   D  EG   +D      +G +   K LD E+ A  +
Sbjct: 470 LTIQATDADEPFTGSSKILYHIIKGD-SEGRLGVDTDPHTNTGYVIIKKPLDFETAAVSN 528

Query: 655 LKAVA------IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708
           +   A      + G     SS     + + D+N++P  F        +SE+  IGT +G 
Sbjct: 529 IVFKAENPEPLVFGVKYNASSFAKFTLIVTDVNEAPQ-FSQHVFQAKVSEDVAIGTKVGN 587

Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE--SPRKKYELV 766
           + A DP EG +  + YS++ GD      ++   G    E+ ++  LD E  SP +   + 
Sbjct: 588 VTAKDP-EGLD--ISYSLR-GDTRGWLKIDHVTG----EIFSVAPLDREAGSPYRVQVVA 639

Query: 767 IRAASPPLWNDVRVEILVTDVNDNAP-VMKDFQIIF 801
                  L +     +++ DVNDN P + KD+  +F
Sbjct: 640 TEVGGSSLSSVSEFHLILMDVNDNPPRLAKDYTGLF 675



 Score =  104 bits (250), Expect = 3e-20
 Identities = 114/412 (27%), Positives = 182/412 (44%), Gaps = 38/412 (9%)

Query: 401 YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQIN 458
           +E+TG  T   F I  +   GL+   + LD +    + L V+A D+ G        + I 
Sbjct: 60  FELTG-ETDNIFVIERE---GLLYYNRALDRETRSTHNLQVAALDANGIIVEGPVPITIK 115

Query: 459 ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD--VGINAQITYSLSSEISNEA 516
           + D N+  P F  + Y  SV +++  G   L V+ATD D     N Q+ Y +  ++    
Sbjct: 116 VKDINDNRPTFLQSKYEGSVRQNSRPGKPFLYVNATDLDDPATPNGQLYYQIVIQLP--- 172

Query: 517 VAHHDQQFVINPQTGAITTNKLLDRETMSG----YLLTVTARD-GGVP--SLSDTTDVEI 569
           + ++   F IN +TGAI+  +   +E        Y L ++ +D GG    S SDTT V+I
Sbjct: 173 MINNVMYFQINNKTGAISLTREGSQELNPAKNPSYNLVISVKDMGGQSENSFSDTTSVDI 232

Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629
            V      E ++K       ++E++   T    +  T       G  +  +D +      
Sbjct: 233 IVT-----ENIWKAPK-PVEMVENS---TDPHPIKITQVRWNDPGAQYSLVDKEKLPRFP 283

Query: 630 FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES 689
           F ID   G I   + LDRE    +   AVA D    P S  + +H+K++DIND+PP   S
Sbjct: 284 FSIDQ-EGDIYVTQPLDREEKDAYVFYAVAKDEYGKPLSYPLEIHVKVKDINDNPPTCPS 342

Query: 690 DCLTFYISENSPIGTTIGEIRAHDPDE--GPNAVVHYSIKGGDD----SNSFSLETRQGS 743
               F + EN  +G +IG + AHD DE    N+ ++Y I            F ++T  G 
Sbjct: 343 PVTVFEVQENERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDGLFLIQTYAG- 401

Query: 744 DKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMK 795
              +L        ++P  +Y L I  +         V+I V D+ND  P+ +
Sbjct: 402 -MLQLAKQSLKKQDTP--QYNLTIEVSDKDFKTLCFVQINVIDINDQIPIFE 450



 Score =  101 bits (243), Expect = 2e-19
 Identities = 116/477 (24%), Positives = 205/477 (42%), Gaps = 50/477 (10%)

Query: 1   MSVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEY 60
           +S P  IH  + V D ND+ P          V+E    G ++ TL A D+D    A    
Sbjct: 320 LSYPLEIH--VKVKDINDNPPTCPSPVTVFEVQENERLGNSIGTLTAHDRDEENTANSFL 377

Query: 61  TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLVKA 119
              +V      P D              +F I   +G L L + SL ++   +Y + ++ 
Sbjct: 378 NYRIVEQTPKLPMDG-------------LFLIQTYAGMLQLAKQSLKKQDTPQYNLTIEV 424

Query: 120 TDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY-TVSVDEDISVTDNPVIAKIKATD 178
           +D+         +   + +N+ID ND  P F +  Y  +++ ED ++     I  I+ATD
Sbjct: 425 SDK------DFKTLCFVQINVIDINDQIPIFEKSDYGNLTLAEDTNI--GSTILTIQATD 476

Query: 179 AD--VGANSAIRYAIIGGNTQMQFSID----SLSGDVSLVKTLDYEQVRSYRLVIRAQD- 231
           AD     +S I Y II G+++ +  +D    + +G V + K LD+E      +V +A++ 
Sbjct: 477 ADEPFTGSSKILYHIIKGDSEGRLGVDTDPHTNTGYVIIKKPLDFETAAVSNIVFKAENP 536

Query: 232 -----GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE 286
                G   + S+  +  + + DVN+ AP+F   +FQ  VSE+V IG  +  V A D  E
Sbjct: 537 EPLVFGVKYNASSFAKFTLIVTDVNE-APQFSQHVFQAKVSEDVAIGTKVGNVTAKD-PE 594

Query: 287 GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR 346
           G+  +++Y++      G+    + ID  +G +++   LDRE  + Y++ V AT+ G    
Sbjct: 595 GL--DISYSL-----RGDTRGWLKIDHVTGEIFSVAPLDREAGSPYRVQVVATEVGGSSL 647

Query: 347 SATATXXXXXXXXXXXXXXFMPGQYEVELAED-EPPGTPVVTLTATDADEDNRLH--YEI 403
           S+ +                      +        PG+ +   T  D       H  + +
Sbjct: 648 SSVSEFHLILMDVNDNPPRLAKDYTGLFFCHPLSAPGSLIFEATDDDQHLFRGPHFTFSL 707

Query: 404 TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT 460
             G+ +  + ++  NG       +  DF +ER YV+ +   D G      +V + +T
Sbjct: 708 GSGSLQNDWEVSKINGTHARLSTRHTDF-EEREYVVLIRINDGGRPPLEGIVSLPVT 763


>UniRef50_P55283 Cluster: Cadherin-4 precursor; n=74; cellular
           organisms|Rep: Cadherin-4 precursor - Homo sapiens
           (Human)
          Length = 916

 Score =  160 bits (389), Expect = 4e-37
 Identities = 160/549 (29%), Positives = 244/549 (44%), Gaps = 50/549 (9%)

Query: 187 IRYAIIG-GNTQ--MQ-FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242
           IRY+I G G  Q  M+ FSIDS+SG + + + +D E+  SY L   A D       N   
Sbjct: 203 IRYSITGVGADQPPMEVFSIDSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNKVENPID 262

Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG--VNAELTYTMTDKD 300
           L I + D+NDN P F   ++  SV E    G  ++ V A DAD+    N  + Y +  + 
Sbjct: 263 LYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQT 322

Query: 301 YTGNVDLPITIDPRSGWVYT-SGQLDRETQAKYQLLVTATD--GG-DPPRSATATXXXXX 356
                    TI+  +G + T +  LDRE   +Y ++V ATD  G  +   S TAT     
Sbjct: 323 PQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITV 382

Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH----YEITGGNTRGRF 412
                    F    +  E+ E+    T V  LT  D D+ +  +    Y I  G+  G F
Sbjct: 383 TDVNDNPPEFTASTFAGEVPENRVE-TVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHF 441

Query: 413 SITSQ--NGRGLITVAQPLDFKQERRYVLTVSATD-----SG---GRSDTAMVQINITDA 462
           S+ +      G++TV + +D++  R ++LTV  ++     SG       TA V I+I D 
Sbjct: 442 SVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPLASGIQMSFQSTAGVTISIMDI 501

Query: 463 NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522
           N  AP F +      + E  P GT +   SA D D  +   + Y   S++S+ A   H  
Sbjct: 502 NE-APYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAVRY---SKLSDPASWLH-- 555

Query: 523 QFVINPQTGAITTNKLLDRETM----SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578
              IN   G ITT  +LDRE++    + Y  T  A D G+P  S T  ++I ++D+NDN 
Sbjct: 556 ---INATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGTLQIYLIDINDNA 612

Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN-GRIHYELD--PKDREEGSFVIDPA 635
           P    +   A I E      +   + A DADV  N G   +EL   P    +   +    
Sbjct: 613 PELLPK--EAQICEKP--NLNAINITAADADVDPNIGPYVFELPFVPAAVRKNWTITRLN 668

Query: 636 SGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695
               + +  +       +D+  +  D G PP S+T I+ +K+   +D+      DC T  
Sbjct: 669 GDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCDDN-----GDCTTIG 723

Query: 696 ISENSPIGT 704
               + +GT
Sbjct: 724 AVAAAGLGT 732



 Score =  149 bits (360), Expect = 1e-33
 Identities = 135/473 (28%), Positives = 218/473 (46%), Gaps = 51/473 (10%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I V+D ND+ P F  Q Y  SV EG+  GT V+T+ A D D    A       +VT    
Sbjct: 265 IYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQ 324

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLT-RASLDREKVARYTVLVKATDQASPVSDR 129
           +P              Q++F I+  +G ++T  A LDREKV +YTV+V+ATD    ++  
Sbjct: 325 SPS-------------QNMFTINSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLNYG 371

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV--GANSAI 187
           LS+TAT  + + D NDN P+F+  T+   V E+   T   V+A +   D D     N   
Sbjct: 372 LSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVET---VVANLTVMDRDQPHSPNWNA 428

Query: 188 RYAIIGGNTQMQFSI--DSLS--GDVSLVKTLDYEQVRSYRLVIRAQD------GGSPSR 237
            Y II G+    FS+  D ++  G V++VK +DYE  R++ L +   +      G   S 
Sbjct: 429 VYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPLASGIQMSF 488

Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297
            +T  + I+I D+N+ AP F ++     + E VP G  +    A D D  +   + Y+  
Sbjct: 489 QSTAGVTISIMDINE-APYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAVRYSKL 547

Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRET----QAKYQLLVTATDGGDPPRSATATXX 353
               +      + I+  +G + T+  LDRE+       Y+    A D G PP S T T  
Sbjct: 548 SDPASW-----LHINATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGTLQ 602

Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH---YEI--TGGNT 408
                        +P + ++     E P    + +TA DAD D  +    +E+       
Sbjct: 603 IYLIDINDNAPELLPKEAQI----CEKPNLNAINITAADADVDPNIGPYVFELPFVPAAV 658

Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINI 459
           R  ++IT  NG     ++  + + +   Y + +  TDSG    S+T+++++ +
Sbjct: 659 RKNWTITRLNG-DYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKV 710



 Score =  136 bits (328), Expect = 1e-29
 Identities = 138/514 (26%), Positives = 217/514 (42%), Gaps = 39/514 (7%)

Query: 88  DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147
           +VF ID  SG +     +DRE+ A Y +   A D      +++ +   +++ +ID NDN 
Sbjct: 218 EVFSIDSMSGRMYVTRPMDREEHASYHLRAHAVDMNG---NKVENPIDLYIYVIDMNDNR 274

Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD--VGANSAIRYAII----GGNTQMQFS 201
           P+F  + Y  SVDE         +  + A DAD    AN  +RY I+       +Q  F+
Sbjct: 275 PEFINQVYNGSVDE--GSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFT 332

Query: 202 IDSLSGD-VSLVKTLDYEQVRSYRLVIRAQD--GG-SPSRSNTTQLLINIRDVNDNAPRF 257
           I+S +GD V++   LD E+V+ Y ++++A D  G  +   SNT   +I + DVNDN P F
Sbjct: 333 INSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEF 392

Query: 258 YTSLFQESVSEN-VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316
             S F   V EN V    + + V   D     N    Y +   D +G+  +        G
Sbjct: 393 TASTFAGEVPENRVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEG 452

Query: 317 WVYTSGQLDRETQAKYQLLVTATD----GGDPPRSATATXXXXXXXXXXXXXXFMPGQYE 372
            V     +D E    + L V  ++          S  +T              + P  ++
Sbjct: 453 MVTVVKAVDYELNRAFMLTVMVSNQAPLASGIQMSFQSTAGVTISIMDINEAPYFPSNHK 512

Query: 373 -VELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429
            + L E  PPGT + T +A D D      + Y     +      I + NG+  IT A  L
Sbjct: 513 LIRLEEGVPPGTVLTTFSAVDPDRFMQQAVRYSKL-SDPASWLHINATNGQ--ITTAAVL 569

Query: 430 D----FKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
           D    + +   Y  T  A D+G    S T  +QI + D N+ AP  E  P  A + E   
Sbjct: 570 DRESLYTKNNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAP--ELLPKEAQICEKPN 627

Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
           +    + ++A D+DV  N    Y         AV  +     +N     ++   L     
Sbjct: 628 L--NAINITAADADVDPNIG-PYVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAG 684

Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577
           M  Y + +   D G P LS+T+ +++ V   +DN
Sbjct: 685 M--YDVPIIVTDSGNPPLSNTSIIKVKVCPCDDN 716



 Score =  126 bits (305), Expect = 7e-27
 Identities = 137/442 (30%), Positives = 192/442 (43%), Gaps = 47/442 (10%)

Query: 391 TDADEDNRLHYEITGGNTRGR----FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446
           +D D D  + Y ITG          FSI S +GR  +T  +P+D ++   Y L   A D 
Sbjct: 195 SDKDNDIPIRYSITGVGADQPPMEVFSIDSMSGRMYVT--RPMDREEHASYHLRAHAVDM 252

Query: 447 GGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD--VGINA 502
            G    +   + I + D N+  P F N  Y  SV E +  GT V+ V+A D+D     N 
Sbjct: 253 NGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADDSTTANG 312

Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL-LDRETMSGYLLTVTARD--GGVP 559
            + Y +   ++    +     F IN +TG I T    LDRE +  Y + V A D  G + 
Sbjct: 313 MVRYRI---VTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLN 369

Query: 560 -SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV--GLNGRI 616
             LS+T    I+V DVNDN P F    +   + E+  V T V+ +   D D     N   
Sbjct: 370 YGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENR-VETVVANLTVMDRDQPHSPNWNA 428

Query: 617 HYELDPKDREEGSFVI--DPAS--GVIRTNKALDRESVATHDLKAVAIDGGTPPQS---- 668
            Y +   D   G F +  DP +  G++   KA+D E      L  V +    P  S    
Sbjct: 429 VYRIISGD-PSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFML-TVMVSNQAPLASGIQM 486

Query: 669 ---STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
              ST  V I I DIN++P  F S+     + E  P GT +    A DPD      V YS
Sbjct: 487 SFQSTAGVTISIMDINEAP-YFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAVRYS 545

Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK---YELVIRAAS---PPLWNDVR 779
            K  D ++   +    G    ++ T   LD ES   K   YE    AA    PP      
Sbjct: 546 -KLSDPASWLHINATNG----QITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGT 600

Query: 780 VEILVTDVNDNAPVM--KDFQI 799
           ++I + D+NDNAP +  K+ QI
Sbjct: 601 LQIYLIDINDNAPELLPKEAQI 622



 Score =  106 bits (255), Expect = 8e-21
 Identities = 97/354 (27%), Positives = 160/354 (45%), Gaps = 24/354 (6%)

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583
           F I+  +G +   + +DRE  + Y L   A D     + +  D+ I V+D+NDN P F  
Sbjct: 220 FSIDSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFIN 279

Query: 584 QLYTANIMEDALVGTSVSQVGATDAD--VGLNGRIHYEL---DPKDREEGSFVIDPASGV 638
           Q+Y  ++ E +  GT V  V A DAD     NG + Y +    P+   +  F I+  +G 
Sbjct: 280 QVYNGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGD 339

Query: 639 IRTNKA-LDRESVATHDL--KAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTF 694
           I T  A LDRE V  + +  +A  ++G      S+T    I + D+ND+PP F +     
Sbjct: 340 IVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAG 399

Query: 695 YISENSPIGTTIGEIRAHDPDE--GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752
            + EN  + T +  +   D D+   PN    Y I  GD S  FS+ T   +++  +  + 
Sbjct: 400 EVPENR-VETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVK 458

Query: 753 DLDYESPRKKYELVIRAASPPLWNDVR--------VEILVTDVNDNAPVMKDFQIIFNNY 804
            +DYE  R     V+ +   PL + ++        V I + D+N+ AP       +    
Sbjct: 459 AVDYELNRAFMLTVMVSNQAPLASGIQMSFQSTAGVTISIMDINE-APYFPSNHKLIRLE 517

Query: 805 KDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
           +   P        A D D  +   ++Y  LS + A+ + +N T G +T +  L+
Sbjct: 518 EGVPPGTVLTTFSAVDPDRFMQQAVRYSKLS-DPASWLHINATNGQITTAAVLD 570


>UniRef50_Q9VEU1 Cluster: Cadherin 89D precursor; n=3;
           Sophophora|Rep: Cadherin 89D precursor - Drosophila
           melanogaster (Fruit fly)
          Length = 2240

 Score =  157 bits (381), Expect = 4e-36
 Identities = 160/561 (28%), Positives = 249/561 (44%), Gaps = 55/561 (9%)

Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR-VQAYDADEG--VNAELTYTMTDK 299
           + + I DVNDNAP F    +   V EN  I   I   VQA+D D+    N+E+ ++M+  
Sbjct: 165 ITVYIEDVNDNAPEFLNVPYVVDVDENTSIESIIFEGVQAFDRDKPNTPNSEVHFSMSTV 224

Query: 300 DYTGNVD-LPITI--DPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDPPRSATATXXXX 355
               + D  P      P    +    +LD +   + ++L + A D G P   A  T    
Sbjct: 225 PEQLSADGSPYFALKSPHRPLLILKRELDFDNGIRQFKLPIFAWDRGTPANQANTTITIN 284

Query: 356 XXXXXXXXXXFMPGQYEVELAEDEP-PGTPV-------VTLTATDADEDNR-LHYEITGG 406
                     F  G Y   + E  P  G P+         + A D D  N  L Y+I  G
Sbjct: 285 VRDVDDLPPKFTEGVYRTRINEFYPMTGVPIRIPLYFAPPIMAFDQDSLNASLVYDIISG 344

Query: 407 NTRGRFSITSQNGRGLITVAQPLDFKQE----RRYVLTVSAT--DSGGRSDTAMVQINIT 460
           N R  F +   NG  ++ + + +D ++E      +VL + A   D+  +   A +++ + 
Sbjct: 345 NERQLFRVNPHNG--VMYLQKEIDLEEESLPGNTFVLQLEARQKDNPLKKALARIEVEVL 402

Query: 461 DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520
           D N+  P FE   Y  S+ E+ P G +VL V+A D D G N++  Y+L  E  + A A  
Sbjct: 403 DLNDNVPEFEADYYNISIVENLPTGFSVLQVNAVDRDQGENSEFLYNLV-ETKDAAGA-- 459

Query: 521 DQQFVINPQTGAITT--NKLLDRETMSGYLLTVTARDGGVPSLSDT---------TDVEI 569
              F I+ +TG IT   ++LLDRE      L V A +     L D            VEI
Sbjct: 460 ---FRIDSRTGWITVRDDRLLDREQRRSIQLNVEALERNPSYLDDKHLKKPGPSKVQVEI 516

Query: 570 SVVDVNDNEPVFKQ-QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD-PKDREE 627
           +++D NDN P F+   LY   +  +A  G  + QV A D D G NG + YEL  PK    
Sbjct: 517 TLLDTNDNTPKFEHGNLYEFKVPINAPTGYVIGQVVAHDPDEGPNGHLLYELQRPKGSGY 576

Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS---STVIVHIKI-EDINDS 683
             F +D  +G I     L R  +A       A D  T P     S  ++ I++   I+D 
Sbjct: 577 IPFRLDNKNGTIYVGGPLRRGRIAVF---VEATDQPTNPSERRFSLAVITIEVYATIDDQ 633

Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
              F      F++  N+P+GT++G++R     EG + +++  +    +   F++E R G 
Sbjct: 634 AIDFVGAPYEFWVGANTPLGTSVGQVRTTLIYEGGDEIMYDLLHTYSEGVPFAIEERSG- 692

Query: 744 DKAELVTMVDLDYESPRKKYE 764
               ++T++    E  RK Y+
Sbjct: 693 ----IITVIRELSEFKRKVYQ 709



 Score =  128 bits (310), Expect = 2e-27
 Identities = 133/519 (25%), Positives = 221/519 (42%), Gaps = 58/519 (11%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-LKATDQDIGK--NAEVEYTIELVTA 67
           + + D ND++P F    Y   V E  S  + +   ++A D+D     N+EV +++  V  
Sbjct: 167 VYIEDVNDNAPEFLNVPYVVDVDENTSIESIIFEGVQAFDRDKPNTPNSEVHFSMSTV-- 224

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREK-VARYTVLVKATDQASPV 126
               PE                         L+ +  LD +  + ++ + + A D+ +P 
Sbjct: 225 ----PEQLSADGSPYFALKSP------HRPLLILKRELDFDNGIRQFKLPIFAWDRGTPA 274

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV------IAKIKATDAD 180
           +    +  TI +N+ D +D  P+F+E  Y   ++E   +T  P+         I A D D
Sbjct: 275 NQ---ANTTITINVRDVDDLPPKFTEGVYRTRINEFYPMTGVPIRIPLYFAPPIMAFDQD 331

Query: 181 VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV----RSYRLVIRAQDGGSPS 236
              N+++ Y II GN +  F ++  +G + L K +D E+      ++ L + A+   +P 
Sbjct: 332 -SLNASLVYDIISGNERQLFRVNPHNGVMYLQKEIDLEEESLPGNTFVLQLEARQKDNPL 390

Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
           +    ++ + + D+NDN P F    +  S+ EN+P G+S+++V A D D+G N+E  Y +
Sbjct: 391 KKALARIEVEVLDLNDNVPEFEADYYNISIVENLPTGFSVLQVNAVDRDQGENSEFLYNL 450

Query: 297 TD-KDYTGNVDLPITIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGG---------DP 344
            + KD  G       ID R+GW+       LDRE +   QL V A +             
Sbjct: 451 VETKDAAG----AFRIDSRTGWITVRDDRLLDREQRRSIQLNVEALERNPSYLDDKHLKK 506

Query: 345 PRSATATXXXXXXXXXXXXXXFMPGQ-YEVELAEDEPPGTPVVTLTATDADE--DNRLHY 401
           P  +                 F  G  YE ++  + P G  +  + A D DE  +  L Y
Sbjct: 507 PGPSKVQVEITLLDTNDNTPKFEHGNLYEFKVPINAPTGYVIGQVVAHDPDEGPNGHLLY 566

Query: 402 EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD-----SGGRSDTAMVQ 456
           E+      G       N  G I V  PL   +  R  + V ATD     S  R   A++ 
Sbjct: 567 ELQRPKGSGYIPFRLDNKNGTIYVGGPL---RRGRIAVFVEATDQPTNPSERRFSLAVIT 623

Query: 457 INI-TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494
           I +    ++ A  F  APY   V  + P+GT+V  V  T
Sbjct: 624 IEVYATIDDQAIDFVGAPYEFWVGANTPLGTSVGQVRTT 662



 Score =  122 bits (294), Expect = 1e-25
 Identities = 138/565 (24%), Positives = 237/565 (41%), Gaps = 48/565 (8%)

Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV--GANSAIRY 189
           S  +I V I D NDN P+F    Y V VDE+ S+ ++ +   ++A D D     NS + +
Sbjct: 161 SYLSITVYIEDVNDNAPEFLNVPYVVDVDENTSI-ESIIFEGVQAFDRDKPNTPNSEVHF 219

Query: 190 AI------IGGNTQMQFSIDSLSGDVSLVK-TLDYEQ-VRSYRLVIRAQDGGSPSRSNTT 241
           ++      +  +    F++ S    + ++K  LD++  +R ++L I A D G+P+    T
Sbjct: 220 SMSTVPEQLSADGSPYFALKSPHRPLLILKRELDFDNGIRQFKLPIFAWDRGTPANQANT 279

Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA-------DEGVNAELTY 294
            + IN+RDV+D  P+F   +++  ++E  P+    +R+  Y A        + +NA L Y
Sbjct: 280 TITINVRDVDDLPPKFTEGVYRTRINEFYPMTGVPIRIPLYFAPPIMAFDQDSLNASLVY 339

Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA----KYQLLVTATDGGDPPRSATA 350
            +     +GN      ++P +G +Y   ++D E ++     + L + A    +P + A A
Sbjct: 340 DI----ISGNERQLFRVNPHNGVMYLQKEIDLEEESLPGNTFVLQLEARQKDNPLKKALA 395

Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR---LHYEITGGN 407
                          F    Y + + E+ P G  V+ + A D D+      L+  +   +
Sbjct: 396 RIEVEVLDLNDNVPEFEADYYNISIVENLPTGFSVLQVNAVDRDQGENSEFLYNLVETKD 455

Query: 408 TRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG---------GRSDTAMVQIN 458
             G F I S+ G   +   + LD +Q R   L V A +            +   + VQ+ 
Sbjct: 456 AAGAFRIDSRTGWITVRDDRLLDREQRRSIQLNVEALERNPSYLDDKHLKKPGPSKVQVE 515

Query: 459 IT--DANNYAPVFENAP-YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515
           IT  D N+  P FE+   Y   V  +AP G  +  V A D D G N  + Y L     + 
Sbjct: 516 ITLLDTNDNTPKFEHGNLYEFKVPINAPTGYVIGQVVAHDPDEGPNGHLLYELQRPKGSG 575

Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575
            +      F ++ + G I     L R  ++ ++                  + I V    
Sbjct: 576 YI-----PFRLDNKNGTIYVGGPLRRGRIAVFVEATDQPTNPSERRFSLAVITIEVYATI 630

Query: 576 DNEPV-FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634
           D++ + F    Y   +  +  +GTSV QV  T    G    I Y+L     E   F I+ 
Sbjct: 631 DDQAIDFVGAPYEFWVGANTPLGTSVGQVRTTLIYEG-GDEIMYDLLHTYSEGVPFAIEE 689

Query: 635 ASGVIRTNKALDRESVATHDLKAVA 659
            SG+I   + L       +  +AVA
Sbjct: 690 RSGIITVIRELSEFKRKVYQFEAVA 714



 Score =  107 bits (258), Expect = 3e-21
 Identities = 100/373 (26%), Positives = 173/373 (46%), Gaps = 38/373 (10%)

Query: 87  QDVFRIDGRSGALLTRASLDREKVA----RYTVLVKATDQASPVSDRLSSTATIHVNIID 142
           + +FR++  +G +  +  +D E+ +     + + ++A  + +P+   L   A I V ++D
Sbjct: 347 RQLFRVNPHNGVMYLQKEIDLEEESLPGNTFVLQLEARQKDNPLKKAL---ARIEVEVLD 403

Query: 143 DNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQM-QFS 201
            NDN P+F    Y +S+ E++    +  + ++ A D D G NS   Y ++        F 
Sbjct: 404 LNDNVPEFEADYYNISIVENLPTGFS--VLQVNAVDRDQGENSEFLYNLVETKDAAGAFR 461

Query: 202 IDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGG----------SPSRSNTTQLLINIRD 249
           IDS +G +++   + LD EQ RS +L + A +             P  S   Q+ I + D
Sbjct: 462 IDSRTGWITVRDDRLLDREQRRSIQLNVEALERNPSYLDDKHLKKPGPSKV-QVEITLLD 520

Query: 250 VNDNAPRF-YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308
            NDN P+F + +L++  V  N P GY I +V A+D DEG N  L Y +     +G +  P
Sbjct: 521 TNDNTPKFEHGNLYEFKVPINAPTGYVIGQVVAHDPDEGPNGHLLYELQRPKGSGYI--P 578

Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR----SATATXXXXXXXXXXXXX 364
             +D ++G +Y  G L R    +  + V ATD    P     S                 
Sbjct: 579 FRLDNKNGTIYVGGPLRR---GRIAVFVEATDQPTNPSERRFSLAVITIEVYATIDDQAI 635

Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRG-RFSITSQNGRGL 422
            F+   YE  +  + P GT V  +  T   E  + + Y++    + G  F+I  ++  G+
Sbjct: 636 DFVGAPYEFWVGANTPLGTSVGQVRTTLIYEGGDEIMYDLLHTYSEGVPFAIEERS--GI 693

Query: 423 ITVAQPL-DFKQE 434
           ITV + L +FK++
Sbjct: 694 ITVIRELSEFKRK 706



 Score =  107 bits (257), Expect = 4e-21
 Identities = 74/219 (33%), Positives = 107/219 (48%), Gaps = 15/219 (6%)

Query: 477  SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA------HHDQQFVINPQT 530
            +++ED P+GT VL +SA+D D G NA + Y L  E             H  + F I+  +
Sbjct: 1178 AIYEDTPVGTKVLQLSASDEDFGKNALLHYELQGEQVERTPGMPMLRVHGVKYFAIDKLS 1237

Query: 531  GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590
            G ++ N  L         LTVT  DG    L D+T +  +V+DVN++ P FK+  Y+ + 
Sbjct: 1238 GELSVNYPLSANIEIMLNLTVTDIDG----LKDSTCLRFTVMDVNNHAPTFKKSWYSFDT 1293

Query: 591  MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650
             E     + + Q+ A D D G N  I Y L         F I PASGV++    LDRE  
Sbjct: 1294 PEGEYKDSVLGQLTAIDMDFGENANITYTLSDSHL---PFTIKPASGVLKIGGQLDRELK 1350

Query: 651  ATHDLKAVAIDGGTPPQ--SSTVIVHIKIEDINDSPPVF 687
              +  + +A D     Q  SS+V V + + DIND+ P F
Sbjct: 1351 DKYSFQVIATDNAPVMQRMSSSVDVEVNVLDINDNRPEF 1389



 Score =  106 bits (254), Expect = 1e-20
 Identities = 104/351 (29%), Positives = 161/351 (45%), Gaps = 56/351 (15%)

Query: 377  EDEPPGTPVVTLTATDAD--EDNRLHYEITGGN---TRGR----------FSITSQNGRG 421
            ED P GT V+ L+A+D D  ++  LHYE+ G     T G           F+I   +G  
Sbjct: 1181 EDTPVGTKVLQLSASDEDFGKNALLHYELQGEQVERTPGMPMLRVHGVKYFAIDKLSGE- 1239

Query: 422  LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
             ++V  PL    E   +L ++ TD  G  D+  ++  + D NN+AP F+ + Y+    E 
Sbjct: 1240 -LSVNYPLSANIE--IMLNLTVTDIDGLKDSTCLRFTVMDVNNHAPTFKKSWYSFDTPEG 1296

Query: 482  APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541
                + +  ++A D D G NA ITY+LS        +H    F I P +G +     LDR
Sbjct: 1297 EYKDSVLGQLTAIDMDFGENANITYTLSD-------SH--LPFTIKPASGVLKIGGQLDR 1347

Query: 542  ETMSGYLLTVTARDGG--VPSLSDTTDVEISVVDVNDNEPVF------------------ 581
            E    Y   V A D    +  +S + DVE++V+D+NDN P F                  
Sbjct: 1348 ELKDKYSFQVIATDNAPVMQRMSSSVDVEVNVLDINDNRPEFIGYDDQTKAVKFIPSVAD 1407

Query: 582  ---KQQLYTANIMEDALVGTSVSQVGATDAD-VGL-NGRIHYELDPKDREEGSFVIDPAS 636
                  +Y A +      GT V Q+ A D D VG  NG + Y +  ++ +   F ID   
Sbjct: 1408 RTLMLPVYKAYLDRSTQPGTFVRQLTAIDKDNVGNGNGLVLYSIRHQEMQAPLFQIDSRD 1467

Query: 637  GVIRTNKALDRESVATH-DLKAVAIDGGTPPQSST--VIVHIKIEDINDSP 684
            G I T   ++  +   H ++  +A D G+P  S+T  VIV+++ + + D P
Sbjct: 1468 GTISTISRINGYNDYEHLNVSVIASDVGSPALSATAIVIVNLQGQAVTDPP 1518



 Score =  105 bits (252), Expect = 2e-20
 Identities = 104/396 (26%), Positives = 180/396 (45%), Gaps = 31/396 (7%)

Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV-VSATDSDVGI--NAQITYSLSSE 511
           + + I D N+ AP F N PY   V E+  I + +   V A D D     N+++ +S+S+ 
Sbjct: 165 ITVYIEDVNDNAPEFLNVPYVVDVDENTSIESIIFEGVQAFDRDKPNTPNSEVHFSMST- 223

Query: 512 ISNEAVAHHDQQFVI-NPQTGAITTNKLLDRET-MSGYLLTVTARDGGVPSLSDTTDVEI 569
           +  +  A     F + +P    +   + LD +  +  + L + A D G P+    T + I
Sbjct: 224 VPEQLSADGSPYFALKSPHRPLLILKRELDFDNGIRQFKLPIFAWDRGTPANQANTTITI 283

Query: 570 SVVDVNDNEPVFKQQLYTANIMED-ALVGTSVS-------QVGATDADVGLNGRIHYELD 621
           +V DV+D  P F + +Y   I E   + G  +         + A D D  LN  + Y++ 
Sbjct: 284 NVRDVDDLPPKFTEGVYRTRINEFYPMTGVPIRIPLYFAPPIMAFDQD-SLNASLVYDII 342

Query: 622 PKDREEGSFVIDPASGVIRTNKALDRESVA----THDLKAVAIDGGTPPQSSTVIVHIKI 677
               E   F ++P +GV+   K +D E  +    T  L+  A     P + +   + +++
Sbjct: 343 -SGNERQLFRVNPHNGVMYLQKEIDLEEESLPGNTFVLQLEARQKDNPLKKALARIEVEV 401

Query: 678 EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS-IKGGDDSNSFS 736
            D+ND+ P FE+D     I EN P G ++ ++ A D D+G N+   Y+ ++  D + +F 
Sbjct: 402 LDLNDNVPEFEADYYNISIVENLPTGFSVLQVNAVDRDQGENSEFLYNLVETKDAAGAFR 461

Query: 737 LETRQG-----SDKA---ELVTMVDLDYES-PRKKYELVIRAASPPLWNDVRVEILVTDV 787
           +++R G      D+    E    + L+ E+  R    L  +    P  + V+VEI + D 
Sbjct: 462 IDSRTGWITVRDDRLLDREQRRSIQLNVEALERNPSYLDDKHLKKPGPSKVQVEITLLDT 521

Query: 788 NDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD 822
           NDN P  +   +         P G   G+V A+D D
Sbjct: 522 NDNTPKFEHGNLYEFKVPINAPTGYVIGQVVAHDPD 557



 Score = 87.8 bits (208), Expect = 4e-15
 Identities = 97/369 (26%), Positives = 160/369 (43%), Gaps = 65/369 (17%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
            +  V+D N+H+P F+   Y     EG    + +  L A D D G+NA + YT+    +D+
Sbjct: 1271 RFTVMDVNNHAPTFKKSWYSFDTPEGEYKDSVLGQLTAIDMDFGENANITYTL----SDS 1326

Query: 70   LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
              P                 F I   SG L     LDRE   +Y+  V ATD A PV  R
Sbjct: 1327 HLP-----------------FTIKPASGVLKIGGQLDRELKDKYSFQVIATDNA-PVMQR 1368

Query: 130  LSSTATIHVNIIDDNDNYPQF----------------SEKTYTVSVDE---DISVTDNPV 170
            +SS+  + VN++D NDN P+F                +++T  + V +   D S      
Sbjct: 1369 MSSSVDVEVNVLDINDNRPEFIGYDDQTKAVKFIPSVADRTLMLPVYKAYLDRSTQPGTF 1428

Query: 171  IAKIKATDAD-VG-ANSAIRYAIIGGNTQMQ-FSIDSLSGDVSLVKTLD-YEQVRSYRLV 226
            + ++ A D D VG  N  + Y+I     Q   F IDS  G +S +  ++ Y       + 
Sbjct: 1429 VRQLTAIDKDNVGNGNGLVLYSIRHQEMQAPLFQIDSRDGTISTISRINGYNDYEHLNVS 1488

Query: 227  IRAQDGGSPSRSNTTQLLINIRD--VND------------NAPRFYTSLFQESVSENVPI 272
            + A D GSP+ S T  +++N++   V D            N   F  + ++  ++EN   
Sbjct: 1489 VIASDVGSPALSATAIVIVNLQGQAVTDPPKSTPKPEPPANVTVFQHAYYEVKLTENNEA 1548

Query: 273  GYSIVRVQAYDADEGVNAE-LTYTMTDKDYTGNVDL--PITIDPRSGWVYTSGQLDRETQ 329
               ++R+   +   G+N E   +++  ++     D   P   D ++  +Y     DRE  
Sbjct: 1549 PIEVMRL---NLSAGLNPENYRWSLWLEEGLDETDAHPPFEYDAKNMLLYALKPFDREHI 1605

Query: 330  AKYQLLVTA 338
            ++YQL + A
Sbjct: 1606 SRYQLRIRA 1614



 Score = 85.0 bits (201), Expect = 3e-14
 Identities = 88/341 (25%), Positives = 150/341 (43%), Gaps = 36/341 (10%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++ VLD ND+ P FE   Y  S+ E   +G +VL + A D+D G+N+E  Y +       
Sbjct: 398 EVEVLDLNDNVPEFEADYYNISIVENLPTGFSVLQVNAVDRDQGENSEFLYNL------- 450

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS--LDREKVARYTVLVKATDQ-ASPV 126
           +  +DA              FRID R+G +  R    LDRE+     + V+A ++  S +
Sbjct: 451 VETKDAA-----------GAFRIDSRTGWITVRDDRLLDREQRRSIQLNVEALERNPSYL 499

Query: 127 SDRL-----SSTATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDAD 180
            D+       S   + + ++D NDN P+F     Y   V   I+     VI ++ A D D
Sbjct: 500 DDKHLKKPGPSKVQVEITLLDTNDNTPKFEHGNLYEFKV--PINAPTGYVIGQVVAHDPD 557

Query: 181 VGANSAIRYAI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238
            G N  + Y +    G+  + F +D+ +G + +   L   ++  +          S  R 
Sbjct: 558 EGPNGHLLYELQRPKGSGYIPFRLDNKNGTIYVGGPLRRGRIAVFVEATDQPTNPSERRF 617

Query: 239 NTTQLLINI-RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297
           +   + I +   ++D A  F  + ++  V  N P+G S+ +V+     EG   E+ Y   
Sbjct: 618 SLAVITIEVYATIDDQAIDFVGAPYEFWVGANTPLGTSVGQVRTTLIYEG-GDEIMY--- 673

Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA 338
           D  +T +  +P  I+ RSG +    +L    +  YQ    A
Sbjct: 674 DLLHTYSEGVPFAIEERSGIITVIRELSEFKRKVYQFEAVA 714



 Score = 75.8 bits (178), Expect = 2e-11
 Identities = 60/190 (31%), Positives = 87/190 (45%), Gaps = 26/190 (13%)

Query: 167  DNPV---IAKIKATDADVGANSAIRYAIIGGNTQMQ-------------FSIDSLSGDVS 210
            D PV   + ++ A+D D G N+ + Y + G   +               F+ID LSG++S
Sbjct: 1182 DTPVGTKVLQLSASDEDFGKNALLHYELQGEQVERTPGMPMLRVHGVKYFAIDKLSGELS 1241

Query: 211  LVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENV 270
            +   L         L +   DG      ++T L   + DVN++AP F  S +     E  
Sbjct: 1242 VNYPLSANIEIMLNLTVTDIDG----LKDSTCLRFTVMDVNNHAPTFKKSWYSFDTPEGE 1297

Query: 271  PIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA 330
                 + ++ A D D G NA +TYT++D        LP TI P SG +   GQLDRE + 
Sbjct: 1298 YKDSVLGQLTAIDMDFGENANITYTLSDSH------LPFTIKPASGVLKIGGQLDRELKD 1351

Query: 331  KYQLLVTATD 340
            KY   V ATD
Sbjct: 1352 KYSFQVIATD 1361



 Score = 72.9 bits (171), Expect = 1e-10
 Identities = 97/380 (25%), Positives = 157/380 (41%), Gaps = 55/380 (14%)

Query: 429  LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
            LD ++++ Y L + A D+GG S  A + + + D N+ AP+FE      SVF+D+ +    
Sbjct: 1047 LDREKQQLYNLKIIAADTGGLSGYAHLTVLVADVNDNAPMFER----ISVFKDSRL---E 1099

Query: 489  LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
            +    TD ++    + +  +++  +  A+      + I    G+   N  +DRE   G  
Sbjct: 1100 IREYTTDMEIYF-VESSSGMTAPQATAAMMLAPPPYHI---PGSPRFN--VDRERSVGAG 1153

Query: 549  LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
            L V AR      +      +  +  + ++ PV                GT V Q+ A+D 
Sbjct: 1154 LGVVARAKSRRRMVRALTTKCPLFAIYEDTPV----------------GTKVLQLSASDE 1197

Query: 609  DVGLNGRIHYELD----------PKDREEG--SFVIDPASGVIRTNKALDRESVATHDLK 656
            D G N  +HYEL           P  R  G   F ID  SG +  N  L        +L 
Sbjct: 1198 DFGKNALLHYELQGEQVERTPGMPMLRVHGVKYFAIDKLSGELSVNYPLSANIEIMLNLT 1257

Query: 657  AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716
               IDG       +  +   + D+N+  P F+    +F   E     + +G++ A D D 
Sbjct: 1258 VTDIDG----LKDSTCLRFTVMDVNNHAPTFKKSWYSFDTPEGEYKDSVLGQLTAIDMDF 1313

Query: 717  GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW- 775
            G NA + Y++   D    F+++   G     L     LD E   K    VI   + P+  
Sbjct: 1314 GENANITYTL--SDSHLPFTIKPASG----VLKIGGQLDRELKDKYSFQVIATDNAPVMQ 1367

Query: 776  ---NDVRVEILVTDVNDNAP 792
               + V VE+ V D+NDN P
Sbjct: 1368 RMSSSVDVEVNVLDINDNRP 1387



 Score = 70.9 bits (166), Expect = 5e-10
 Identities = 87/345 (25%), Positives = 142/345 (41%), Gaps = 44/345 (12%)

Query: 31   SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDV- 89
            ++ E    GT VL L A+D+D GKNA + Y ++         E            V  V 
Sbjct: 1178 AIYEDTPVGTKVLQLSASDEDFGKNALLHYELQ--------GEQVERTPGMPMLRVHGVK 1229

Query: 90   -FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
             F ID  SG L     L     A   +++  T   + + D L  +  +   ++D N++ P
Sbjct: 1230 YFAIDKLSGELSVNYPLS----ANIEIMLNLT--VTDI-DGLKDSTCLRFTVMDVNNHAP 1282

Query: 149  QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208
             F +  Y+    E     D+ V+ ++ A D D G N+ I Y +   ++ + F+I   SG 
Sbjct: 1283 TFKKSWYSFDTPEG-EYKDS-VLGQLTAIDMDFGENANITYTL--SDSHLPFTIKPASGV 1338

Query: 209  VSLVKTLDYEQVRSYRLVIRAQDGGSPSR--SNTTQLLINIRDVNDNAPRFYTSLFQESV 266
            + +   LD E    Y   + A D     +  S++  + +N+ D+NDN P F     Q   
Sbjct: 1339 LKIGGQLDRELKDKYSFQVIATDNAPVMQRMSSSVDVEVNVLDINDNRPEFIGYDDQTKA 1398

Query: 267  SENVP-IGYSIVRVQAYDA--DEGVNAEL---TYTMTDKDYTGN-------------VDL 307
             + +P +    + +  Y A  D            T  DKD  GN             +  
Sbjct: 1399 VKFIPSVADRTLMLPVYKAYLDRSTQPGTFVRQLTAIDKDNVGNGNGLVLYSIRHQEMQA 1458

Query: 308  PI-TIDPRSGWVYTSGQLDRETQAKY-QLLVTATDGGDPPRSATA 350
            P+  ID R G + T  +++     ++  + V A+D G P  SATA
Sbjct: 1459 PLFQIDSRDGTISTISRINGYNDYEHLNVSVIASDVGSPALSATA 1503



 Score = 62.1 bits (144), Expect = 2e-07
 Identities = 76/285 (26%), Positives = 122/285 (42%), Gaps = 27/285 (9%)

Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV--DVNDNEPVFKQQLYTAN 589
           A +  +L+DR+     L       G    L + + + I+V   DVNDN P F    Y  +
Sbjct: 128 ARSLERLVDRDVPRNLLKFRILCAGKQEKLEEGSYLSITVYIEDVNDNAPEFLNVPYVVD 187

Query: 590 IMEDALVGTSVSQ-VGATDADVGL--NGRIHYELDPKDRE---EGS--FVI-DPASGVIR 640
           + E+  + + + + V A D D     N  +H+ +     +   +GS  F +  P   ++ 
Sbjct: 188 VDENTSIESIIFEGVQAFDRDKPNTPNSEVHFSMSTVPEQLSADGSPYFALKSPHRPLLI 247

Query: 641 TNKALDRES-VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699
             + LD ++ +    L   A D GTP   +   + I + D++D PP F        I+E 
Sbjct: 248 LKRELDFDNGIRQFKLPIFAWDRGTPANQANTTITINVRDVDDLPPKFTEGVYRTRINEF 307

Query: 700 SPI-GTTIG-------EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751
            P+ G  I         I A D D   NA + Y I  G++   F +    G     L   
Sbjct: 308 YPMTGVPIRIPLYFAPPIMAFDQDS-LNASLVYDIISGNERQLFRVNPHNGV--MYLQKE 364

Query: 752 VDLDYES-PRKKYELVIRAASP--PLWNDV-RVEILVTDVNDNAP 792
           +DL+ ES P   + L + A     PL   + R+E+ V D+NDN P
Sbjct: 365 IDLEEESLPGNTFVLQLEARQKDNPLKKALARIEVEVLDLNDNVP 409



 Score = 60.9 bits (141), Expect = 5e-07
 Identities = 93/382 (24%), Positives = 157/382 (41%), Gaps = 53/382 (13%)

Query: 10   QINVLDCNDHSPVF-EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA- 67
            ++NVLD ND+ P F        +V+   S     L L      + ++ +    +  +TA 
Sbjct: 1376 EVNVLDINDNRPEFIGYDDQTKAVKFIPSVADRTLMLPVYKAYLDRSTQPGTFVRQLTAI 1435

Query: 68   --DTLNPEDAXXXXXXXXXXVQ-DVFRIDGRSGALLTRASLDR-EKVARYTVLVKATDQA 123
              D +   +           +Q  +F+ID R G + T + ++         V V A+D  
Sbjct: 1436 DKDNVGNGNGLVLYSIRHQEMQAPLFQIDSRDGTISTISRINGYNDYEHLNVSVIASDVG 1495

Query: 124  SPVSDRLSSTATIHVNI----IDDNDNYPQFSEKTYTVSVDE----DISVTDN-PVIAKI 174
            SP    LS+TA + VN+    + D        E    V+V +    ++ +T+N     ++
Sbjct: 1496 SPA---LSATAIVIVNLQGQAVTDPPKSTPKPEPPANVTVFQHAYYEVKLTENNEAPIEV 1552

Query: 175  KATDADVGANSA-------IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVI 227
               +   G N         +   +   +    F  D+ +  +  +K  D E +  Y+L I
Sbjct: 1553 MRLNLSAGLNPENYRWSLWLEEGLDETDAHPPFEYDAKNMLLYALKPFDREHISRYQLRI 1612

Query: 228  RAQDGGSPSRS------------------NTTQLLINIRDVNDNAPRFYTS--LFQESVS 267
            RA      +R+                  N  ++L++I D NDNAP+F  +       + 
Sbjct: 1613 RADRLSREARNYARVSYPVVDERIEGLSLNECRILVHIADENDNAPKFRGNGQPIVAVLP 1672

Query: 268  ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327
            ++   GY + RV+A D DEG+NAE+ Y + ++           ID  SG +   G+L R 
Sbjct: 1673 QSASFGYPVTRVEANDLDEGLNAEIRYRLLNEPAR-----LFGIDELSGNIRLLGELSR- 1726

Query: 328  TQAKYQLLVTATD--GGDPPRS 347
            T+  Y   V ATD  G D  RS
Sbjct: 1727 TEHIYGFDVKATDRMGADDGRS 1748



 Score = 57.2 bits (132), Expect = 6e-06
 Identities = 36/111 (32%), Positives = 56/111 (50%), Gaps = 5/111 (4%)

Query: 637 GVIRTNKALDRESVATHDLKAVA-IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695
           G + T   LDRE   +++L  +     G    +    V+IK++D+ND+ P F +      
Sbjct: 876 GTLLTLTGLDREQQPSYELTVIVEYSTGLVSGAGIYQVNIKVDDVNDNAPKFNALTYVGL 935

Query: 696 ISENSPIGTTIG---EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743
           I+EN  +GT +     I   D DEGPNA     ++ GD S+ FS+E   G+
Sbjct: 936 INENCVVGTELSMNHAILIQDADEGPNAEFRVQLQ-GDYSDEFSIEYVNGT 985



 Score = 54.0 bits (124), Expect = 6e-05
 Identities = 49/176 (27%), Positives = 80/176 (45%), Gaps = 21/176 (11%)

Query: 90   FRIDGRSGALLTRASLDREKVARYTVLVKATDQAS-----------PVSDR----LS-ST 133
            F  D ++  L      DRE ++RY + ++A D+ S           PV D     LS + 
Sbjct: 1585 FEYDAKNMLLYALKPFDREHISRYQLRIRA-DRLSREARNYARVSYPVVDERIEGLSLNE 1643

Query: 134  ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG 193
              I V+I D+NDN P+F      +      S +    + +++A D D G N+ IRY ++ 
Sbjct: 1644 CRILVHIADENDNAPKFRGNGQPIVAVLPQSASFGYPVTRVEANDLDEGLNAEIRYRLLN 1703

Query: 194  GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD--GGSPSRSNTTQLLINI 247
               ++ F ID LSG++ L+  L   +   Y   ++A D  G    RS    + + I
Sbjct: 1704 EPARL-FGIDELSGNIRLLGELSRTE-HIYGFDVKATDRMGADDGRSGIVNVFVYI 1757



 Score = 53.2 bits (122), Expect = 1e-04
 Identities = 56/212 (26%), Positives = 102/212 (48%), Gaps = 26/212 (12%)

Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE-IRAHDPDE--GPNAVVH 723
           + S + + + IED+ND+ P F +      + EN+ I + I E ++A D D+   PN+ VH
Sbjct: 159 EGSYLSITVYIEDVNDNAPEFLNVPYVVDVDENTSIESIIFEGVQAFDRDKPNTPNSEVH 218

Query: 724 YSIK------GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPL 774
           +S+         D S  F+L++     +  L+   +LD+++  ++++L I A    +P  
Sbjct: 219 FSMSTVPEQLSADGSPYFALKS---PHRPLLILKRELDFDNGIRQFKLPIFAWDRGTPAN 275

Query: 775 WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVP--------AYDAD-VT 824
             +  + I V DV+D  P   +  +      + +P+ G   R+P        A+D D + 
Sbjct: 276 QANTTITINVRDVDDLPPKFTE-GVYRTRINEFYPMTGVPIRIPLYFAPPIMAFDQDSLN 334

Query: 825 DKLQYRILSGNNANLILLNETTGSMTLSPQLN 856
             L Y I+SGN   L  +N   G M L  +++
Sbjct: 335 ASLVYDIISGNERQLFRVNPHNGVMYLQKEID 366



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 43/115 (37%), Positives = 58/115 (50%), Gaps = 8/115 (6%)

Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRL-VIRAQDGGSPSRSN 239
           AN  +RY I   N Q   +  S++ D +L+    LD EQ  SY L VI     G  S + 
Sbjct: 852 ANIKLRYII--ANQQEVVNKISITEDGTLLTLTGLDREQQPSYELTVIVEYSTGLVSGAG 909

Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA---YDADEGVNAE 291
             Q+ I + DVNDNAP+F    +   ++EN  +G  +    A    DADEG NAE
Sbjct: 910 IYQVNIKVDDVNDNAPKFNALTYVGLINENCVVGTELSMNHAILIQDADEGPNAE 964



 Score = 52.8 bits (121), Expect = 1e-04
 Identities = 45/130 (34%), Positives = 58/130 (44%), Gaps = 10/130 (7%)

Query: 521 DQQFVINP----QTGAITTNKLLDRETMSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVN 575
           +QQ V+N     + G + T   LDRE    Y LTV      G+ S +    V I V DVN
Sbjct: 862 NQQEVVNKISITEDGTLLTLTGLDREQQPSYELTVIVEYSTGLVSGAGIYQVNIKVDDVN 921

Query: 576 DNEPVFKQQLYTANIMEDALVGTSVSQVGA---TDADVGLNGRIHYELDPKDREEGSFVI 632
           DN P F    Y   I E+ +VGT +S   A    DAD G N     +L     +E  F I
Sbjct: 922 DNAPKFNALTYVGLINENCVVGTELSMNHAILIQDADEGPNAEFRVQLQGDYSDE--FSI 979

Query: 633 DPASGVIRTN 642
           +  +G    N
Sbjct: 980 EYVNGTSSEN 989



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 36/115 (31%), Positives = 57/115 (49%), Gaps = 4/115 (3%)

Query: 97  GALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT 156
           G LLT   LDRE+   Y + V        VS   +    +++ + D NDN P+F+  TY 
Sbjct: 876 GTLLTLTGLDREQQPSYELTVIVEYSTGLVSG--AGIYQVNIKVDDVNDNAPKFNALTYV 933

Query: 157 VSVDEDISV-TDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVS 210
             ++E+  V T+  +   I   DAD G N+  R  + G  +  +FSI+ ++G  S
Sbjct: 934 GLINENCVVGTELSMNHAILIQDADEGPNAEFRVQLQGDYSD-EFSIEYVNGTSS 987



 Score = 48.8 bits (111), Expect = 0.002
 Identities = 113/548 (20%), Positives = 206/548 (37%), Gaps = 77/548 (14%)

Query: 265  SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI---------TIDPRS 315
            ++ E+ P+G  ++++ A D D G NA L Y +  +       +P+          ID  S
Sbjct: 1178 AIYEDTPVGTKVLQLSASDEDFGKNALLHYELQGEQVERTPGMPMLRVHGVKYFAIDKLS 1237

Query: 316  GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375
            G +  +  L    +    L VT  DG       +                F    Y  + 
Sbjct: 1238 GELSVNYPLSANIEIMLNLTVTDIDG----LKDSTCLRFTVMDVNNHAPTFKKSWYSFDT 1293

Query: 376  AEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435
             E E   + +  LTA D D     +   T  ++   F+I  +   G++ +   LD + + 
Sbjct: 1294 PEGEYKDSVLGQLTAIDMDFGENANITYTLSDSHLPFTI--KPASGVLKIGGQLDRELKD 1351

Query: 436  RYVLTVSATDSG----GRSDTAMVQINITDANNYAPVF---ENAPYTASVFEDAPIGTTV 488
            +Y   V ATD+       S +  V++N+ D N+  P F   ++              T +
Sbjct: 1352 KYSFQVIATDNAPVMQRMSSSVDVEVNVLDINDNRPEFIGYDDQTKAVKFIPSVADRTLM 1411

Query: 489  LVVSATDSDVGIN-----AQITYSLSSEISN------EAVAHHDQQ---FVINPQTGAIT 534
            L V     D          Q+T      + N       ++ H + Q   F I+ + G I+
Sbjct: 1412 LPVYKAYLDRSTQPGTFVRQLTAIDKDNVGNGNGLVLYSIRHQEMQAPLFQIDSRDGTIS 1471

Query: 535  TNKLLDRETMSGYL-LTVTARDGGVPSLSDTTDVEI-----SVVDVNDNEP--------- 579
            T   ++      +L ++V A D G P+LS T  V +     +V D   + P         
Sbjct: 1472 TISRINGYNDYEHLNVSVIASDVGSPALSATAIVIVNLQGQAVTDPPKSTPKPEPPANVT 1531

Query: 580  VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR----IHYELDPKDREEGSFVIDPA 635
            VF+   Y   + E+      V ++  +      N R    +   LD  D     F  D  
Sbjct: 1532 VFQHAYYEVKLTENNEAPIEVMRLNLSAGLNPENYRWSLWLEEGLDETDAHP-PFEYDAK 1590

Query: 636  SGVIRTNKALDRESVATHDLK----AVAIDGGTPPQSSTVIVHIKIE------------- 678
            + ++   K  DRE ++ + L+     ++ +     + S  +V  +IE             
Sbjct: 1591 NMLLYALKPFDREHISRYQLRIRADRLSREARNYARVSYPVVDERIEGLSLNECRILVHI 1650

Query: 679  -DINDSPPVFESD--CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735
             D ND+ P F  +   +   + +++  G  +  + A+D DEG NA + Y +   + +  F
Sbjct: 1651 ADENDNAPKFRGNGQPIVAVLPQSASFGYPVTRVEANDLDEGLNAEIRYRLL-NEPARLF 1709

Query: 736  SLETRQGS 743
             ++   G+
Sbjct: 1710 GIDELSGN 1717



 Score = 46.4 bits (105), Expect = 0.011
 Identities = 41/196 (20%), Positives = 81/196 (41%), Gaps = 7/196 (3%)

Query: 691  CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE-TRQGSDKAELV 749
            C  F I E++P+GT + ++ A D D G NA++HY ++G     +  +   R    K   +
Sbjct: 1174 CPLFAIYEDTPVGTKVLQLSASDEDFGKNALLHYELQGEQVERTPGMPMLRVHGVKYFAI 1233

Query: 750  TMV--DLDYESP-RKKYELVIRAASPP---LWNDVRVEILVTDVNDNAPVMKDFQIIFNN 803
              +  +L    P     E+++         L +   +   V DVN++AP  K     F+ 
Sbjct: 1234 DKLSGELSVNYPLSANIEIMLNLTVTDIDGLKDSTCLRFTVMDVNNHAPTFKKSWYSFDT 1293

Query: 804  YKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLA 863
             +  +     G++ A D D  +         ++     +   +G + +  QL+  +    
Sbjct: 1294 PEGEYKDSVLGQLTAIDMDFGENANITYTLSDSHLPFTIKPASGVLKIGGQLDRELKDKY 1353

Query: 864  TMEVSVTDGVNEIKAM 879
            + +V  TD    ++ M
Sbjct: 1354 SFQVIATDNAPVMQRM 1369



 Score = 42.7 bits (96), Expect = 0.14
 Identities = 38/129 (29%), Positives = 57/129 (44%), Gaps = 10/129 (7%)

Query: 394 DEDNRLHYEITGGN-TRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR-SD 451
           D + +L Y I        + SIT     G +     LD +Q+  Y LTV    S G  S 
Sbjct: 851 DANIKLRYIIANQQEVVNKISITED---GTLLTLTGLDREQQPSYELTVIVEYSTGLVSG 907

Query: 452 TAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVLV---VSATDSDVGINAQITY 506
             + Q+NI   D N+ AP F    Y   + E+  +GT + +   +   D+D G NA+   
Sbjct: 908 AGIYQVNIKVDDVNDNAPKFNALTYVGLINENCVVGTELSMNHAILIQDADEGPNAEFRV 967

Query: 507 SLSSEISNE 515
            L  + S+E
Sbjct: 968 QLQGDYSDE 976


>UniRef50_UPI000065EA0C Cluster: Cadherin-20 precursor.; n=1;
           Takifugu rubripes|Rep: Cadherin-20 precursor. - Takifugu
           rubripes
          Length = 878

 Score =  156 bits (378), Expect = 9e-36
 Identities = 109/349 (31%), Positives = 176/349 (50%), Gaps = 28/349 (8%)

Query: 391 TDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA----TD 445
           +D D+ D  + Y +TG      F+I    G   I   Q LD + + +YVL   A    TD
Sbjct: 37  SDMDKGDGSIKYILTGEGAGTTFTIDDNTGD--IHAIQRLDREMKAQYVLRAQARNRLTD 94

Query: 446 SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505
                ++  + + I D N+  P F + PY A+V E + IGT+V+ ++ATD+D       T
Sbjct: 95  RPLEPESEFI-VKIQDINDNEPRFLDGPYWATVPEMSQIGTSVIQLTATDAD-----DPT 148

Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGAITTNKL-LDRETMSGYLLTVTARD--GGVPSLS 562
           Y  S+ +   ++      F ++ +TG +  +   +DRET   Y + + A+D  G +  L+
Sbjct: 149 YGNSARVVY-SILEGQPYFSVDAKTGVLRVSLADMDRETRENYSVVIQAKDMGGQMGGLA 207

Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-D 621
            TT V I++ D+NDN P+F Q+LY  +I E A +G+ V ++ A D D+G+N  + Y + D
Sbjct: 208 GTTTVNITLTDINDNPPMFDQRLYQMSIPEAAPMGSVVGRIWAKDRDIGINAEMRYSIID 267

Query: 622 PKDREEGSFVIDPAS--GVIRTNKALDRESVATHDLKAVAIDGGTPPQ-------SSTVI 672
              R+      DP +  G+I   K LD E+  ++ LK    +    P            I
Sbjct: 268 GDGRDTFDVSTDPTNLFGIITVKKPLDFETKPSYTLKVEGANTQVDPLFHHHGPFKDVTI 327

Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721
           VH+ +ED+ D PP+F+S      + E++ IGT +  + A DPD   N V
Sbjct: 328 VHVSVEDV-DEPPLFDSPGYYIELPEDAEIGTVVKTVSARDPDSANNTV 375



 Score =  144 bits (349), Expect = 3e-32
 Identities = 161/626 (25%), Positives = 276/626 (44%), Gaps = 78/626 (12%)

Query: 177 TDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG-GSP 235
           +D D G  S I+Y + G      F+ID  +GD+  ++ LD E    Y L  +A++     
Sbjct: 37  SDMDKGDGS-IKYILTGEGAGTTFTIDDNTGDIHAIQRLDREMKAQYVLRAQARNRLTDR 95

Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE---GVNAEL 292
                ++ ++ I+D+NDN PRF    +  +V E   IG S++++ A DAD+   G +A +
Sbjct: 96  PLEPESEFIVKIQDINDNEPRFLDGPYWATVPEMSQIGTSVIQLTATDADDPTYGNSARV 155

Query: 293 TYTMTD-KDYTGNVDLPITIDPRSGWVYTS-GQLDRETQAKYQLLVTATD-GGDPPRSA- 348
            Y++ + + Y        ++D ++G +  S   +DRET+  Y +++ A D GG     A 
Sbjct: 156 VYSILEGQPY-------FSVDAKTGVLRVSLADMDRETRENYSVVIQAKDMGGQMGGLAG 208

Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGG 406
           T T              F    Y++ + E  P G+ V  + A D D   +  + Y I  G
Sbjct: 209 TTTVNITLTDINDNPPMFDQRLYQMSIPEAAPMGSVVGRIWAKDRDIGINAEMRYSIIDG 268

Query: 407 NTRGRFSITSQ--NGRGLITVAQPLDFKQERRYVLTVSATDS---------GGRSDTAMV 455
           + R  F +++   N  G+ITV +PLDF+ +  Y L V   ++         G   D  +V
Sbjct: 269 DGRDTFDVSTDPTNLFGIITVKKPLDFETKPSYTLKVEGANTQVDPLFHHHGPFKDVTIV 328

Query: 456 QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515
            +++ D +   P+F++  Y   + EDA IGT V  VSA D D   N     S   ++ N 
Sbjct: 329 HVSVEDVDE-PPLFDSPGYYIELPEDAEIGTVVKTVSARDPDSANNT--VRSPPQDVIN- 384

Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV-VDV 574
              +  Q+  +  +   +T       E ++G  L V    GGV  +    D  + + + +
Sbjct: 385 --CYTTQRLKVKER--LVTLTGYTRAEMVNG--LVVLGLGGGVVLIKTINDYALRLSLRL 438

Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI------HYELDPKDREEG 628
           +    V +Q   + +        TS ++ GA   +  +NG +       Y ++  +  + 
Sbjct: 439 SIIWGVGQQAAASLSGF------TSWNRDGAGGWEALMNGCMCCFGVCRYSIERTNDLDK 492

Query: 629 SFVIDPASGVIRTNKALDRESVATHDLKAVAID------------GGT------------ 664
            F ID  SG + T + LDRE ++ H++  +A++             G+            
Sbjct: 493 YFYIDITSGALMTVRTLDREEMSWHNITVLAMEMRLGPGKWTLAPSGSLVIRVCVCVSTD 552

Query: 665 -PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
            P Q ++V V IKI D+ND+PP   +  L  Y+ EN+  G  I  + A D DE       
Sbjct: 553 NPSQIASVSVAIKITDVNDNPPSL-THYLEAYVCENAKAGQLIQMVTAVDVDEPQGGQHF 611

Query: 724 YSIKGGDDSNSFSLETRQGSDKAELV 749
           Y     + +N+ +   R   D    V
Sbjct: 612 YYSLAPEAANNPNFTLRDNQDNTAWV 637



 Score =  124 bits (300), Expect = 3e-26
 Identities = 106/324 (32%), Positives = 159/324 (49%), Gaps = 26/324 (8%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR-LSSTATIHVNIIDDNDNYP 148
           F ID  +G +     LDRE  A+Y +  +A ++   ++DR L   +   V I D NDN P
Sbjct: 59  FTIDDNTGDIHAIQRLDREMKAQYVLRAQARNR---LTDRPLEPESEFIVKIQDINDNEP 115

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDAD---VGANSAIRYAIIGGNTQMQFSIDSL 205
           +F +  Y  +V E +S     VI ++ ATDAD    G ++ + Y+I+ G  Q  FS+D+ 
Sbjct: 116 RFLDGPYWATVPE-MSQIGTSVI-QLTATDADDPTYGNSARVVYSILEG--QPYFSVDAK 171

Query: 206 SGDVSL-VKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQLLINIRDVNDNAPRFYTSLF 262
           +G + + +  +D E   +Y +VI+A+D G      + TT + I + D+NDN P F   L+
Sbjct: 172 TGVLRVSLADMDRETRENYSVVIQAKDMGGQMGGLAGTTTVNITLTDINDNPPMFDQRLY 231

Query: 263 QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS--GWVYT 320
           Q S+ E  P+G  + R+ A D D G+NAE+ Y++ D D  G     ++ DP +  G +  
Sbjct: 232 QMSIPEAAPMGSVVGRIWAKDRDIGINAEMRYSIIDGD--GRDTFDVSTDPTNLFGIITV 289

Query: 321 SGQLDRETQAKYQLLVT-ATDGGDP------PRSATATXXXXXXXXXXXXXXFMPGQYEV 373
              LD ET+  Y L V  A    DP      P                      PG Y +
Sbjct: 290 KKPLDFETKPSYTLKVEGANTQVDPLFHHHGPFKDVTIVHVSVEDVDEPPLFDSPGYY-I 348

Query: 374 ELAEDEPPGTPVVTLTATDADEDN 397
           EL ED   GT V T++A D D  N
Sbjct: 349 ELPEDAEIGTVVKTVSARDPDSAN 372



 Score =  120 bits (290), Expect = 4e-25
 Identities = 84/255 (32%), Positives = 131/255 (51%), Gaps = 11/255 (4%)

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFK 582
           F I+  TG I   + LDRE  + Y+L   AR+      L   ++  + + D+NDNEP F 
Sbjct: 59  FTIDDNTGDIHAIQRLDREMKAQYVLRAQARNRLTDRPLEPESEFIVKIQDINDNEPRFL 118

Query: 583 QQLYTANIMEDALVGTSVSQVGATDAD---VGLNGRIHYELDPKDREEGSFVIDPASGVI 639
              Y A + E + +GTSV Q+ ATDAD    G + R+ Y +      +  F +D  +GV+
Sbjct: 119 DGPYWATVPEMSQIGTSVIQLTATDADDPTYGNSARVVYSIL---EGQPYFSVDAKTGVL 175

Query: 640 RTNKA-LDRESVATHDLKAVAID--GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696
           R + A +DRE+   + +   A D  G     + T  V+I + DIND+PP+F+       I
Sbjct: 176 RVSLADMDRETRENYSVVIQAKDMGGQMGGLAGTTTVNITLTDINDNPPMFDQRLYQMSI 235

Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756
            E +P+G+ +G I A D D G NA + YSI  GD  ++F + T   +    +     LD+
Sbjct: 236 PEAAPMGSVVGRIWAKDRDIGINAEMRYSIIDGDGRDTFDVSTDPTNLFGIITVKKPLDF 295

Query: 757 ESPRKKYELVIRAAS 771
           E+ +  Y L +  A+
Sbjct: 296 ET-KPSYTLKVEGAN 309



 Score =  102 bits (245), Expect = 1e-19
 Identities = 85/294 (28%), Positives = 140/294 (47%), Gaps = 40/294 (13%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVTA 67
           + + D ND+ P F    Y A+V E +  GT+V+ L ATD D    G +A V Y+I     
Sbjct: 105 VKIQDINDNEPRFLDGPYWATVPEMSQIGTSVIQLTATDADDPTYGNSARVVYSI----- 159

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLVKATDQASPV 126
                              Q  F +D ++G L ++ A +DRE    Y+V+++A D    +
Sbjct: 160 ----------------LEGQPYFSVDAKTGVLRVSLADMDRETRENYSVVIQAKDMGGQM 203

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
              L+ T T+++ + D NDN P F ++ Y +S+ E  +     V+ +I A D D+G N+ 
Sbjct: 204 GG-LAGTTTVNITLTDINDNPPMFDQRLYQMSIPE--AAPMGSVVGRIWAKDRDIGINAE 260

Query: 187 IRYAIIGGNTQMQFSID----SLSGDVSLVKTLDYEQVRSYRLVIR-AQDGGSP------ 235
           +RY+II G+ +  F +     +L G +++ K LD+E   SY L +  A     P      
Sbjct: 261 MRYSIIDGDGRDTFDVSTDPTNLFGIITVKKPLDFETKPSYTLKVEGANTQVDPLFHHHG 320

Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN 289
              + T + +++ DV D  P F +  +   + E+  IG  +  V A D D   N
Sbjct: 321 PFKDVTIVHVSVEDV-DEPPLFDSPGYYIELPEDAEIGTVVKTVSARDPDSANN 373



 Score = 80.2 bits (189), Expect = 8e-13
 Identities = 79/245 (32%), Positives = 124/245 (50%), Gaps = 27/245 (11%)

Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA----ID 661
           +D D G +G I Y L  +     +F ID  +G I   + LDRE  A + L+A A     D
Sbjct: 37  SDMDKG-DGSIKYILTGEGAGT-TFTIDDNTGDIHAIQRLDREMKAQYVLRAQARNRLTD 94

Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE---GP 718
               P+S  ++   KI+DIND+ P F        + E S IGT++ ++ A D D+   G 
Sbjct: 95  RPLEPESEFIV---KIQDINDNEPRFLDGPYWATVPEMSQIGTSVIQLTATDADDPTYGN 151

Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP----- 773
           +A V YSI  G     FS++ + G  +   V++ D+D E+ R+ Y +VI+A         
Sbjct: 152 SARVVYSILEGQPY--FSVDAKTGVLR---VSLADMDRET-RENYSVVIQAKDMGGQMGG 205

Query: 774 LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDAD--VTDKLQYR 830
           L     V I +TD+NDN P M D ++   +  +  P+G   GR+ A D D  +  +++Y 
Sbjct: 206 LAGTTTVNITLTDINDNPP-MFDQRLYQMSIPEAAPMGSVVGRIWAKDRDIGINAEMRYS 264

Query: 831 ILSGN 835
           I+ G+
Sbjct: 265 IIDGD 269



 Score = 61.7 bits (143), Expect = 3e-07
 Identities = 51/182 (28%), Positives = 83/182 (45%), Gaps = 23/182 (12%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I + D ND+ P+F+ + Y+ S+ E A  G+ V  + A D+DIG NAE+ Y+I  +  D  
Sbjct: 214 ITLTDINDNPPMFDQRLYQMSIPEAAPMGSVVGRIWAKDRDIGINAEMRYSI--IDGDGR 271

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVK-ATDQASPVSDR 129
           +  D             ++F      G +  +  LD E    YT+ V+ A  Q  P+   
Sbjct: 272 DTFDVSTDPT-------NLF------GIITVKKPLDFETKPSYTLKVEGANTQVDPLFHH 318

Query: 130 ---LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
                    +HV+ ++D D  P F    Y + + ED  +    V+  + A D D  AN+ 
Sbjct: 319 HGPFKDVTIVHVS-VEDVDEPPLFDSPGYYIELPEDAEI--GTVVKTVSARDPD-SANNT 374

Query: 187 IR 188
           +R
Sbjct: 375 VR 376



 Score = 40.7 bits (91), Expect = 0.57
 Identities = 30/109 (27%), Positives = 46/109 (42%), Gaps = 3/109 (2%)

Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293
           +PS+  +  + I I DVNDN P   T   +  V EN   G  I  V A D DE    +  
Sbjct: 553 NPSQIASVSVAIKITDVNDNPPSL-THYLEAYVCENAKAGQLIQMVTAVDVDEPQGGQHF 611

Query: 294 YTMTDKDYTGNVDLPITID-PRSGWVYT-SGQLDRETQAKYQLLVTATD 340
           Y     +   N +  +  +   + WV T  G   ++ Q  + L +  +D
Sbjct: 612 YYSLAPEAANNPNFTLRDNQDNTAWVLTRRGGWSQQQQTVFHLPIIISD 660


>UniRef50_UPI0000E81ECF Cluster: PREDICTED: similar to protocadherin
           beta 20; n=2; Gallus gallus|Rep: PREDICTED: similar to
           protocadherin beta 20 - Gallus gallus
          Length = 808

 Score =  155 bits (376), Expect = 2e-35
 Identities = 121/387 (31%), Positives = 189/387 (48%), Gaps = 18/387 (4%)

Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM---VQINITDANNYA 466
           GR     + G G + VA+ LD ++      T +       +D      +++++ D N+++
Sbjct: 226 GRQHFRLERGSGRLVVAERLDREEMCGRSRTCTLAFELLLADPLQFFPIEVSVEDINDHS 285

Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526
           PVF +   T  + E +  GT   V +A D D+G N    YS+  E  NE      Q    
Sbjct: 286 PVFPDERVTFKIPETSDPGTRFPVGAAQDLDIGSNDIQAYSIIPE--NEFFTVFTQSE-- 341

Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586
           + +   +   K LDRE  S    T+ A DGG P  + +T++ I V+D+NDN PVF Q+LY
Sbjct: 342 SSKYVELVLEKPLDREEQSELDFTLVATDGGSPPRTGSTEIHIVVLDINDNVPVFTQKLY 401

Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKAL 645
             +++E+A  G+ V +V A DAD G+NG I Y+         S F I+  +G I   K L
Sbjct: 402 IGHVLENAPEGSVVLRVVANDADEGVNGDISYQFSQSAGHSHSLFTINSRTGEIVIAKPL 461

Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
           D E+   H+    AIDGG    SS   V +++ D+ND+ P          I EN   GT 
Sbjct: 462 DFETAQKHEFTVQAIDGG--GFSSMCNVVVEVLDVNDNAPEIAVTSFNSPILENVEPGTV 519

Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765
           +  +   D D G N  +  ++   ++   F+L      +  ELVT+  LD E  R ++ +
Sbjct: 520 VALLAVSDQDSGVNGEITCAL---EEQLYFALRP-AFKNYYELVTVSTLDREE-RAQHMV 574

Query: 766 VIRAA---SPPLWNDVRVEILVTDVND 789
           V+ AA   SPPL +     + ++DVN+
Sbjct: 575 VVTAADAGSPPLTSTHTFSVDISDVNE 601



 Score =  149 bits (360), Expect = 1e-33
 Identities = 107/347 (30%), Positives = 167/347 (48%), Gaps = 35/347 (10%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           +++V D NDHSPVF  ++    + E +  GT      A D DIG N         + A +
Sbjct: 275 EVSVEDINDHSPVFPDERVTFKIPETSDPGTRFPVGAAQDLDIGSND--------IQAYS 326

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
           + PE+            + V         L+    LDRE+ +     + ATD  SP   R
Sbjct: 327 IIPENEFFTVFTQSESSKYV--------ELVLEKPLDREEQSELDFTLVATDGGSP--PR 376

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             ST  IH+ ++D NDN P F++K Y   V E  +  +  V+ ++ A DAD G N  I Y
Sbjct: 377 TGST-EIHIVVLDINDNVPVFTQKLYIGHVLE--NAPEGSVVLRVVANDADEGVNGDISY 433

Query: 190 AI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
                 G++   F+I+S +G++ + K LD+E  + +   ++A DGG    S+   +++ +
Sbjct: 434 QFSQSAGHSHSLFTINSRTGEIVIAKPLDFETAQKHEFTVQAIDGG--GFSSMCNVVVEV 491

Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307
            DVNDNAP    + F   + ENV  G  +  +   D D GVN E+T  + ++ Y      
Sbjct: 492 LDVNDNAPEIAVTSFNSPILENVEPGTVVALLAVSDQDSGVNGEITCALEEQLY------ 545

Query: 308 PITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351
              + P     Y   T   LDRE +A++ ++VTA D G PP ++T T
Sbjct: 546 -FALRPAFKNYYELVTVSTLDREERAQHMVVVTAADAGSPPLTSTHT 591



 Score =  145 bits (351), Expect = 2e-32
 Identities = 104/318 (32%), Positives = 153/318 (48%), Gaps = 19/318 (5%)

Query: 374 ELAEDEPPGT--PVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL-ITVAQPLD 430
           ++ E   PGT  PV      D   ++   Y I   N        S++ + + + + +PLD
Sbjct: 296 KIPETSDPGTRFPVGAAQDLDIGSNDIQAYSIIPENEFFTVFTQSESSKYVELVLEKPLD 355

Query: 431 FKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTV 488
            +++     T+ ATD G    T   +I+I   D N+  PVF    Y   V E+AP G+ V
Sbjct: 356 REEQSELDFTLVATDGGSPPRTGSTEIHIVVLDINDNVPVFTQKLYIGHVLENAPEGSVV 415

Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548
           L V A D+D G+N  I+Y  S     ++  H    F IN +TG I   K LD ET   + 
Sbjct: 416 LRVVANDADEGVNGDISYQFS-----QSAGHSHSLFTINSRTGEIVIAKPLDFETAQKHE 470

Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608
            TV A DGG    S   +V + V+DVNDN P      + + I+E+   GT V+ +  +D 
Sbjct: 471 FTVQAIDGG--GFSSMCNVVVEVLDVNDNAPEIAVTSFNSPILENVEPGTVVALLAVSDQ 528

Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASG---VIRTNKALDRESVATHDLKAVAIDGGTP 665
           D G+NG I   L+    E+  F + PA      + T   LDRE  A H +   A D G+P
Sbjct: 529 DSGVNGEITCALE----EQLYFALRPAFKNYYELVTVSTLDREERAQHMVVVTAADAGSP 584

Query: 666 PQSSTVIVHIKIEDINDS 683
           P +ST    + I D+N++
Sbjct: 585 PLTSTHTFSVDISDVNEA 602



 Score =  134 bits (325), Expect = 3e-29
 Identities = 96/345 (27%), Positives = 156/345 (45%), Gaps = 25/345 (7%)

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           +++ D+ND++P F        + E    G       A D D G N    Y++  ++    
Sbjct: 276 VSVEDINDHSPVFPDERVTFKIPETSDPGTRFPVGAAQDLDIGSNDIQAYSIIPENEFFT 335

Query: 305 VDLPITIDPRSGWV--YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362
           V    T    S +V       LDRE Q++    + ATDGG PPR+ +             
Sbjct: 336 V---FTQSESSKYVELVLEKPLDREEQSELDFTLVATDGGSPPRTGSTEIHIVVLDINDN 392

Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADE----DNRLHYEITGGNTRGRFSITSQN 418
              F    Y   + E+ P G+ V+ + A DADE    D    +  + G++   F+I S+ 
Sbjct: 393 VPVFTQKLYIGHVLENAPEGSVVLRVVANDADEGVNGDISYQFSQSAGHSHSLFTINSRT 452

Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASV 478
           G   I +A+PLDF+  +++  TV A D GG S    V + + D N+ AP      + + +
Sbjct: 453 GE--IVIAKPLDFETAQKHEFTVQAIDGGGFSSMCNVVVEVLDVNDNAPEIAVTSFNSPI 510

Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP---QTGAITT 535
            E+   GT V +++ +D D G+N +IT +L  ++           F + P       + T
Sbjct: 511 LENVEPGTVVALLAVSDQDSGVNGEITCALEEQL----------YFALRPAFKNYYELVT 560

Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVND-NEP 579
              LDRE  + +++ VTA D G P L+ T    + + DVN+  EP
Sbjct: 561 VSTLDREERAQHMVVVTAADAGSPPLTSTHTFSVDISDVNEATEP 605



 Score =  134 bits (324), Expect = 3e-29
 Identities = 119/384 (30%), Positives = 187/384 (48%), Gaps = 23/384 (5%)

Query: 90  FRIDGRSGALLTRASLDREKVA-RYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           FR++  SG L+    LDRE++  R      A +    ++D L     I V++ D ND+ P
Sbjct: 230 FRLERGSGRLVVAERLDREEMCGRSRTCTLAFELL--LADPLQFFP-IEVSVEDINDHSP 286

Query: 149 QFSEKTYTVSVDEDISV-TDNPVIAKIKATDADVGANSAIRYAIIGGN---TQMQFSIDS 204
            F ++  T  + E     T  PV A   A D D+G+N    Y+II  N   T    S  S
Sbjct: 287 VFPDERVTFKIPETSDPGTRFPVGA---AQDLDIGSNDIQAYSIIPENEFFTVFTQSESS 343

Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
              ++ L K LD E+       + A DGGSP R+ +T++ I + D+NDN P F   L+  
Sbjct: 344 KYVELVLEKPLDREEQSELDFTLVATDGGSPPRTGSTEIHIVVLDINDNVPVFTQKLYIG 403

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
            V EN P G  ++RV A DADEGVN +++Y  +     G+     TI+ R+G +  +  L
Sbjct: 404 HVLENAPEGSVVLRVVANDADEGVNGDISYQFSQS--AGHSHSLFTINSRTGEIVIAKPL 461

Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
           D ET  K++  V A DGG    S+                      +   + E+  PGT 
Sbjct: 462 DFETAQKHEFTVQAIDGGG--FSSMCNVVVEVLDVNDNAPEIAVTSFNSPILENVEPGT- 518

Query: 385 VVTLTATDADEDNRLHYEITGG-NTRGRFSI--TSQNGRGLITVAQPLDFKQERRYVLTV 441
           VV L A  +D+D+ ++ EIT     +  F++    +N   L+TV+  LD ++  ++++ V
Sbjct: 519 VVALLAV-SDQDSGVNGEITCALEEQLYFALRPAFKNYYELVTVS-TLDREERAQHMVVV 576

Query: 442 SATDSGG--RSDTAMVQINITDAN 463
           +A D+G    + T    ++I+D N
Sbjct: 577 TAADAGSPPLTSTHTFSVDISDVN 600



 Score =  134 bits (323), Expect = 4e-29
 Identities = 101/326 (30%), Positives = 158/326 (48%), Gaps = 17/326 (5%)

Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532
           P   SV E+   G+ V  V+    D G+      +  + I++ A   H   F +   +G 
Sbjct: 185 PIRYSVAEEGESGSVVADVA---EDAGLAPAQLSARRARIASPAGRQH---FRLERGSGR 238

Query: 533 ITTNKLLDRETMSGYLLTVT-ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591
           +   + LDRE M G   T T A +  +        +E+SV D+ND+ PVF  +  T  I 
Sbjct: 239 LVVAERLDREEMCGRSRTCTLAFELLLADPLQFFPIEVSVEDINDHSPVFPDERVTFKIP 298

Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT--NKALDRES 649
           E +  GT      A D D+G N    Y + P++     F    +S  +     K LDRE 
Sbjct: 299 ETSDPGTRFPVGAAQDLDIGSNDIQAYSIIPENEFFTVFTQSESSKYVELVLEKPLDREE 358

Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709
            +  D   VA DGG+PP++ +  +HI + DIND+ PVF       ++ EN+P G+ +  +
Sbjct: 359 QSELDFTLVATDGGSPPRTGSTEIHIVVLDINDNVPVFTQKLYIGHVLENAPEGSVVLRV 418

Query: 710 RAHDPDEGPNAVVHY--SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767
            A+D DEG N  + Y  S   G   + F++ +R G    E+V    LD+E+ +K +E  +
Sbjct: 419 VANDADEGVNGDISYQFSQSAGHSHSLFTINSRTG----EIVIAKPLDFETAQK-HEFTV 473

Query: 768 RAASPPLWNDV-RVEILVTDVNDNAP 792
           +A     ++ +  V + V DVNDNAP
Sbjct: 474 QAIDGGGFSSMCNVVVEVLDVNDNAP 499



 Score = 86.6 bits (205), Expect = 9e-15
 Identities = 67/245 (27%), Positives = 110/245 (44%), Gaps = 30/245 (12%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70
           I VLD ND+ PVF  + Y   V E A  G+ VL + A D D G N ++ Y        + 
Sbjct: 384 IVVLDINDNVPVFTQKLYIGHVLENAPEGSVVLRVVANDADEGVNGDISYQFSQSAGHS- 442

Query: 71  NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130
                             +F I+ R+G ++    LD E   ++   V+A D         
Sbjct: 443 ----------------HSLFTINSRTGEIVIAKPLDFETAQKHEFTVQAIDGGG-----F 481

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190
           SS   + V ++D NDN P+ +  ++   + E++      V+A +  +D D G N  I  A
Sbjct: 482 SSMCNVVVEVLDVNDNAPEIAVTSFNSPILENVE--PGTVVALLAVSDQDSGVNGEITCA 539

Query: 191 IIGGNTQMQFSIDSLSG---DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247
           +     Q+ F++        ++  V TLD E+   + +V+ A D GSP  ++T    ++I
Sbjct: 540 L---EEQLYFALRPAFKNYYELVTVSTLDREERAQHMVVVTAADAGSPPLTSTHTFSVDI 596

Query: 248 RDVND 252
            DVN+
Sbjct: 597 SDVNE 601



 Score = 83.0 bits (196), Expect = 1e-13
 Identities = 84/296 (28%), Positives = 131/296 (44%), Gaps = 18/296 (6%)

Query: 589 NIMEDALVGTSVSQVGATDADVG---LNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645
           ++ E+   G+ V+ V A DA +    L+ R      P  R+   F ++  SG +   + L
Sbjct: 189 SVAEEGESGSVVADV-AEDAGLAPAQLSARRARIASPAGRQH--FRLERGSGRLVVAERL 245

Query: 646 DRESVATHDLKA-VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
           DRE +        +A +           + + +EDIND  PVF  + +TF I E S  GT
Sbjct: 246 DREEMCGRSRTCTLAFELLLADPLQFFPIEVSVEDINDHSPVFPDERVTFKIPETSDPGT 305

Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK-AELVTMVDLDYESPRK-K 762
                 A D D G N +  YSI    ++  F++ T+  S K  ELV    LD E   +  
Sbjct: 306 RFPVGAAQDLDIGSNDIQAYSII--PENEFFTVFTQSESSKYVELVLEKPLDREEQSELD 363

Query: 763 YELVIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYD 820
           + LV     SPP      + I+V D+NDN PV    ++   +  +  P G    RV A D
Sbjct: 364 FTLVATDGGSPPRTGSTEIHIVVLDINDNVPVFTQ-KLYIGHVLENAPEGSVVLRVVAND 422

Query: 821 AD--VTDKLQYRI--LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
           AD  V   + Y+    +G++ +L  +N  TG + ++  L+    +     V   DG
Sbjct: 423 ADEGVNGDISYQFSQSAGHSHSLFTINSRTGEIVIAKPLDFETAQKHEFTVQAIDG 478


>UniRef50_P12830 Cluster: Epithelial cadherin precursor (E-cadherin)
           (Uvomorulin) (Cadherin-1) (CAM 120/80) (CD324 antigen)
           [Contains: E-Cad/CTF1; E-Cad/CTF2; E- Cad/CTF3]; n=52;
           Tetrapoda|Rep: Epithelial cadherin precursor
           (E-cadherin) (Uvomorulin) (Cadherin-1) (CAM 120/80)
           (CD324 antigen) [Contains: E-Cad/CTF1; E-Cad/CTF2; E-
           Cad/CTF3] - Homo sapiens (Human)
          Length = 882

 Score =  154 bits (373), Expect = 4e-35
 Identities = 122/401 (30%), Positives = 189/401 (47%), Gaps = 31/401 (7%)

Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259
           F I+  +G + + + LD E++ +Y L   A      +  +  ++LI + D NDN P F  
Sbjct: 205 FIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQ 264

Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGV---NAELTYTMTDKDYTGNVDLPITIDPRSG 316
            +F+ SV E    G S++ V A DAD+ V   NA + YT+  +D         TI+  +G
Sbjct: 265 EVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTG 324

Query: 317 --WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374
              V T+G LDRE+   Y L+V A D      S TAT              F P  Y+ +
Sbjct: 325 VISVVTTG-LDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQ 383

Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITG---GNTRGRFSITSQ--NGRGLITVAQPL 429
           + E+E     + TL  TDAD  N   +E       +  G+F +T+   N  G++  A+ L
Sbjct: 384 VPENE-ANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGL 442

Query: 430 DFKQERRYVLTVSAT-----DSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
           DF+ +++Y+L V+ T     +    + TA V +++ D N  AP+F        V ED  +
Sbjct: 443 DFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNE-APIFVPPEKRVEVSEDFGV 501

Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
           G  +   +A + D  +  +ITY +  + +N           INP TGAI+T   LDRE  
Sbjct: 502 GQEITSYTAQEPDTFMEQKITYRIWRDTAN--------WLEINPDTGAISTRAELDREDF 553

Query: 545 -----SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580
                S Y   + A D G P  + T  + + + DVNDN P+
Sbjct: 554 EHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPI 594



 Score =  136 bits (328), Expect = 1e-29
 Identities = 122/430 (28%), Positives = 192/430 (44%), Gaps = 26/430 (6%)

Query: 391 TDADEDNRLHYEITGGNTR----GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446
           ++ D++ ++ Y ITG        G F I  + G   + V +PLD ++   Y L   A  S
Sbjct: 180 SNKDKEGKVFYSITGQGADTPPVGVFIIERETG--WLKVTEPLDRERIATYTLFSHAVSS 237

Query: 447 GGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504
            G +  D   + I +TD N+  P F    +  SV E A  GT+V+ V+ATD+D  +N   
Sbjct: 238 NGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYN 297

Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL-LDRETMSGYLLTVTARDGGVPSLSD 563
                + +S +        F IN  TG I+     LDRE+   Y L V A D     LS 
Sbjct: 298 AAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLST 357

Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK 623
           T    I+V D NDN P+F    Y   + E+      ++ +  TDAD              
Sbjct: 358 TATAVITVTDTNDNPPIFNPTTYKGQVPENE-ANVVITTLKVTDADAPNTPAWEAVYTIL 416

Query: 624 DREEGSFVI--DPAS--GVIRTNKALDRESVATHDLKAVAIDGGTPPQ----SSTVIVHI 675
           + + G FV+  +P +  G+++T K LD E+   + L  VA+    P +    +ST  V +
Sbjct: 417 NDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILH-VAVTNVVPFEVSLTTSTATVTV 475

Query: 676 KIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735
            + D+N++P +F        +SE+  +G  I    A +PD      + Y I   D +N  
Sbjct: 476 DVLDVNEAP-IFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRI-WRDTANWL 533

Query: 736 SLETRQG--SDKAELVTMVDLDYESPRKKYELVIRA--ASPPLWNDVRVEILVTDVNDNA 791
            +    G  S +AEL    D ++        L+I     SP       + ++++DVNDNA
Sbjct: 534 EINPDTGAISTRAEL-DREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNA 592

Query: 792 PVMKDFQIIF 801
           P+ +   I F
Sbjct: 593 PIPEPRTIFF 602



 Score =  118 bits (285), Expect = 2e-24
 Identities = 139/531 (26%), Positives = 233/531 (43%), Gaps = 44/531 (8%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           VF I+  +G L     LDRE++A YT+   A    S   + +     I + + D NDN P
Sbjct: 204 VFIIERETGWLKVTEPLDRERIATYTLFSHA---VSSNGNAVEDPMEILITVTDQNDNKP 260

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA---NSAIRYAIIGGNTQM----QFS 201
           +F+++ +  SV E         + ++ ATDAD      N+AI Y I+  + ++     F+
Sbjct: 261 EFTQEVFKGSVME--GALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFT 318

Query: 202 IDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260
           I+  +G +S+V T LD E   +Y LV++A D      S T   +I + D NDN P F  +
Sbjct: 319 INRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPT 378

Query: 261 LFQESVSEN-VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP--RSGW 317
            ++  V EN   +  + ++V   DA      E  YT+ + D        +T +P    G 
Sbjct: 379 TYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDD---GGQFVVTTNPVNNDGI 435

Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX--FMPGQYEVEL 375
           + T+  LD E + +Y L V  T+      S T +                F+P +  VE+
Sbjct: 436 LKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEV 495

Query: 376 AEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQ--PLDF 431
           +ED   G  + + TA + D   + ++ Y I   +T     I    G  + T A+    DF
Sbjct: 496 SEDFGVGQEITSYTAQEPDTFMEQKITYRI-WRDTANWLEINPDTG-AISTRAELDREDF 553

Query: 432 KQERR--YVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487
           +  +   Y   + ATD+G    + T  + + ++D N+ AP+ E  P T    E  P    
Sbjct: 554 EHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPE--PRTIFFCERNP---K 608

Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
             V++  D+D+  N   T   ++E+++ A A+   Q+    Q   I   K+     +  Y
Sbjct: 609 PQVINIIDADLPPN---TSPFTAELTHGASANWTIQYNDPTQESIILKPKM--ALEVGDY 663

Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF-KQQLYTANIMEDALVG 597
            + +   D    +    T +E+SV D      V  K Q   A +   A++G
Sbjct: 664 KINLKLMDN--QNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILG 712



 Score =  118 bits (284), Expect = 2e-24
 Identities = 131/493 (26%), Positives = 213/493 (43%), Gaps = 48/493 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKN---AEVEYTIELVTA 67
           I V D ND+ P F  + ++ SV EGA  GT+V+ + ATD D   N   A + YTI  ++ 
Sbjct: 250 ITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTI--LSQ 307

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLVKATDQASPV 126
           D   P+             +++F I+  +G + +    LDRE    YT++V+A D     
Sbjct: 308 DPELPD-------------KNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQG-- 352

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
            + LS+TAT  + + D NDN P F+  TY   V E+ +   N VI  +K TDAD     A
Sbjct: 353 -EGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEA---NVVITTLKVTDADAPNTPA 408

Query: 187 IR--YAII---GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241
               Y I+   GG   +  +  +  G +   K LD+E  + Y L +   +      S TT
Sbjct: 409 WEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTT 468

Query: 242 Q---LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298
               + +++ DVN+ AP F     +  VSE+  +G  I    A + D  +  ++TY +  
Sbjct: 469 STATVTVDVLDVNE-APIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIW- 526

Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRE-----TQAKYQLLVTATDGGDPPRSATATXX 353
           +D T N    + I+P +G + T  +LDRE       + Y  L+ ATD G P   AT T  
Sbjct: 527 RD-TANW---LEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSP--VATGTGT 580

Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS 413
                        +P    +   E  P    +  + A      +    E+T G     ++
Sbjct: 581 LLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHG-ASANWT 639

Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENA- 472
           I   +      + +P    +   Y + +   D+  +     +++++ D    A V   A 
Sbjct: 640 IQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQ 699

Query: 473 PYTASVFEDAPIG 485
           P  A +   A +G
Sbjct: 700 PVEAGLQIPAILG 712



 Score =  118 bits (283), Expect = 3e-24
 Identities = 106/353 (30%), Positives = 168/353 (47%), Gaps = 28/353 (7%)

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583
           F+I  +TG +   + LDRE ++ Y L   A      ++ D  ++ I+V D NDN+P F Q
Sbjct: 205 FIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQ 264

Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGL---NGRIHYEL---DPKDREEGSFVIDPASG 637
           +++  ++ME AL GTSV +V ATDAD  +   N  I Y +   DP+  ++  F I+  +G
Sbjct: 265 EVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTG 324

Query: 638 VIR-TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696
           VI      LDRES  T+ L   A D      S+T    I + D ND+PP+F        +
Sbjct: 325 VISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQV 384

Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG--GDDSNSFSLETRQGSDKAELVTMVDL 754
            EN      I  ++  D D  PN     ++     DD   F + T   ++   L T   L
Sbjct: 385 PENE-ANVVITTLKVTDAD-APNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGL 442

Query: 755 DYESPRKKYELVIRAAS-PPL-----WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCF 808
           D+E+ +++Y L +   +  P       +   V + V DVN+ AP+    +      +D F
Sbjct: 443 DFEA-KQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNE-APIFVPPEKRVEVSED-F 499

Query: 809 PVGPFGRVPAYDADVTD-----KLQYRILSGNNANLILLNETTGSMTLSPQLN 856
            VG    + +Y A   D     K+ YRI   + AN + +N  TG+++   +L+
Sbjct: 500 GVGQ--EITSYTAQEPDTFMEQKITYRIWR-DTANWLEINPDTGAISTRAELD 549



 Score =  111 bits (266), Expect = 4e-22
 Identities = 119/468 (25%), Positives = 196/468 (41%), Gaps = 33/468 (7%)

Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326
           +E  P   ++V++++    EG   ++ Y++T +           I+  +GW+  +  LDR
Sbjct: 166 NEKGPFPKNLVQIKSNKDKEG---KVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDR 222

Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386
           E  A Y L   A                           F    ++  + E   PGT V+
Sbjct: 223 ERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVM 282

Query: 387 TLTATDADEDNRLH-----YEITGGNTR--GRFSITSQNGRGLITVAQP-LDFKQERRYV 438
            +TATDAD+D   +     Y I   +     +   T     G+I+V    LD +    Y 
Sbjct: 283 EVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYT 342

Query: 439 LTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFE-DAPIGTTVLVVSATD 495
           L V A D  G   S TA   I +TD N+  P+F    Y   V E +A +  T L V+  D
Sbjct: 343 LVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDAD 402

Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555
           +      +  Y++ ++   + V   +    +N   G + T K LD E    Y+L V   +
Sbjct: 403 APNTPAWEAVYTILNDDGGQFVVTTNP---VN-NDGILKTAKGLDFEAKQQYILHVAVTN 458

Query: 556 G---GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612
                V   + T  V + V+DVN+  P+F        + ED  VG  ++   A + D  +
Sbjct: 459 VVPFEVSLTTSTATVTVDVLDVNE-APIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFM 517

Query: 613 NGRIHYELDPKDREEGSFV-IDPASGVIRTNKALDRESV-----ATHDLKAVAIDGGTPP 666
             +I Y +    R+  +++ I+P +G I T   LDRE       +T+    +A D G+P 
Sbjct: 518 EQKITYRIW---RDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPV 574

Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714
            + T  + + + D+ND+ P+ E    T +  E +P    I  I A  P
Sbjct: 575 ATGTGTLLLILSDVNDNAPIPEP--RTIFFCERNPKPQVINIIDADLP 620


>UniRef50_Q96LQ7 Cluster: CDNA FLJ25193 fis, clone JTH00761; n=13;
           Euteleostomi|Rep: CDNA FLJ25193 fis, clone JTH00761 -
           Homo sapiens (Human)
          Length = 493

 Score =  153 bits (372), Expect = 5e-35
 Identities = 135/415 (32%), Positives = 197/415 (47%), Gaps = 41/415 (9%)

Query: 169 PVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIR 228
           PV+     +D D G     +Y + G      F ID  +G++ + K+LD E+   Y L+ +
Sbjct: 62  PVLIGKLHSDVDRGEGRT-KYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLLAQ 120

Query: 229 AQDGGSPSRSNT-TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE- 286
           A D  S       ++ +I ++D+NDN P F    +  +V E   +G S+++V A+DAD+ 
Sbjct: 121 AVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDP 180

Query: 287 --GVNAELTYTMTDKDYTGNVDLPI-TIDPRSGWVYTS-GQLDRETQAKYQLLVTATDGG 342
             G +A+L YT+ D        LP  ++DP++G V T+   +DRETQ ++ +++ A D G
Sbjct: 181 SYGNSAKLVYTVLD-------GLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMG 233

Query: 343 DPPR--SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD-EDNRL 399
                 S + T              F    Y+  + E   PGT V  L A D D  DN L
Sbjct: 234 GHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNAL 293

Query: 400 H-YEITGGNTRGRFSI-TSQNGR-GLITVAQPLDFKQERRYVLTVSATDS---------G 447
             Y I  G     FSI T   GR GL+TV +PLDF+ +R Y   V AT++         G
Sbjct: 294 MAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRG 353

Query: 448 GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507
              D A V++ + DA    P F  A Y  +V E+   GT V  +SA D D         S
Sbjct: 354 PFKDVASVRVAVQDAPE-PPAFTQAAYHLTVPENKAPGTLVGQISAADLD---------S 403

Query: 508 LSSEISNEAVAHHDQQ--FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560
            +S I    + H D +  F I P+ G I T   LDRE  + + LTV A + G  S
Sbjct: 404 PASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGEDS 458



 Score =  138 bits (335), Expect = 2e-30
 Identities = 114/374 (30%), Positives = 178/374 (47%), Gaps = 34/374 (9%)

Query: 391 TDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR 449
           +D D  + R  Y +TG      F I    G   I V + LD +++ +YVL   A D    
Sbjct: 70  SDVDRGEGRTKYLLTGEGAGTVFVIDEATGN--IHVTKSLDREEKAQYVLLAQAVDRASN 127

Query: 450 ---SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD---VGINAQ 503
                 +   I + D N+  P+F   PY A+V E + +GT+V+ V+A D+D    G +A+
Sbjct: 128 RPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAK 187

Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTN-KLLDRETMSGYLLTVTARD--GGVPS 560
           + Y++   +           F ++PQTG + T    +DRET   +L+ + A+D  G +  
Sbjct: 188 LVYTVLDGLPF---------FSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGG 238

Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE- 619
           LS +T V +++ DVNDN P F Q LY  +++E A  GT V ++ A D D+G N  + Y  
Sbjct: 239 LSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSI 298

Query: 620 LDPKDREEGSFVID--PASGVIRTNKALDRESVATHDLKAVA----IDGG---TPPQSST 670
           LD +  E  S   D     G++   K LD ES  ++  +  A    ID       P    
Sbjct: 299 LDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDV 358

Query: 671 VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-KGG 729
             V + ++D  + PP F        + EN   GT +G+I A D D  P + + YSI    
Sbjct: 359 ASVRVAVQDAPE-PPAFTQAAYHLTVPENKAPGTLVGQISAADLD-SPASPIRYSILPHS 416

Query: 730 DDSNSFSLETRQGS 743
           D    FS++  +G+
Sbjct: 417 DPERCFSIQPEEGT 430



 Score =  128 bits (309), Expect = 2e-27
 Identities = 111/371 (29%), Positives = 172/371 (46%), Gaps = 18/371 (4%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           VF ID  +G +    SLDRE+ A+Y +L +A D+AS  +  L   +   + + D NDN P
Sbjct: 91  VFVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRAS--NRPLEPPSEFIIKVQDINDNPP 148

Query: 149 QFSEKTYTVSVDEDISVTDNPV-IAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207
            F    Y  +V E  +V  + + +    A D   G ++ + Y ++ G     FS+D  +G
Sbjct: 149 IFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPF--FSVDPQTG 206

Query: 208 DV-SLVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQLLINIRDVNDNAPRFYTSLFQE 264
            V + +  +D E    + +VI+A+D G      S +T + + + DVNDN P+F  SL+Q 
Sbjct: 207 VVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQF 266

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
           SV E    G  + R++A D D G NA + Y++ D + +    +   +  R G +     L
Sbjct: 267 SVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPL 326

Query: 325 DRETQAKYQLLVTATDG-GDPPRSATATXXXXXXXXXXXXX-----XFMPGQYEVELAED 378
           D E+Q  Y   V AT+   DP                          F    Y + + E+
Sbjct: 327 DFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPEN 386

Query: 379 EPPGTPVVTLTATDADED-NRLHYEITGGNTRGR-FSITSQNGRGLITVAQPLDFKQERR 436
           + PGT V  ++A D D   + + Y I   +   R FSI  Q   G I  A PLD +    
Sbjct: 387 KAPGTLVGQISAADLDSPASPIRYSILPHSDPERCFSI--QPEEGTIHTAAPLDREARAW 444

Query: 437 YVLTVSATDSG 447
           + LTV AT+ G
Sbjct: 445 HNLTVLATELG 455



 Score =  128 bits (308), Expect = 3e-27
 Identities = 116/399 (29%), Positives = 174/399 (43%), Gaps = 32/399 (8%)

Query: 283 DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD-G 341
           D D G      Y +T +   G V     ID  +G ++ +  LDRE +A+Y LL  A D  
Sbjct: 71  DVDRG-EGRTKYLLTGEG-AGTV---FVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRA 125

Query: 342 GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN---- 397
            + P    +               F  G Y   + E    GT V+ +TA DAD+ +    
Sbjct: 126 SNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNS 185

Query: 398 -RLHYEITGGNTRGRFSITSQNGRGLITVAQP-LDFKQERRYVLTVSATDSGGR----SD 451
            +L Y +  G     FS+  Q G  ++  A P +D + +  +++ + A D GG     S 
Sbjct: 186 AKLVYTVLDGLPF--FSVDPQTG--VVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSG 241

Query: 452 TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE 511
           +  V + ++D N+  P F  + Y  SV E A  GT V  + A D D+G NA + YS+   
Sbjct: 242 STTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDG 301

Query: 512 ISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV-PS------LSDT 564
             +EA +       +  + G +T  K LD E+   Y   V A +  + P+        D 
Sbjct: 302 EGSEAFSISTD---LQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDV 358

Query: 565 TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624
             V ++V D  +  P F Q  Y   + E+   GT V Q+ A D D   +  I Y + P  
Sbjct: 359 ASVRVAVQDAPE-PPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPAS-PIRYSILPHS 416

Query: 625 REEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663
             E  F I P  G I T   LDRE+ A H+L  +A + G
Sbjct: 417 DPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELG 455



 Score =  127 bits (306), Expect = 5e-27
 Identities = 94/257 (36%), Positives = 131/257 (50%), Gaps = 15/257 (5%)

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFK 582
           FVI+  TG I   K LDRE  + Y+L   A D      L   ++  I V D+NDN P+F 
Sbjct: 92  FVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFP 151

Query: 583 QQLYTANIMEDALVGTSVSQVGATDAD---VGLNGRIHYE-LDPKDREEGSFVIDPASGV 638
              Y A + E + VGTSV QV A DAD    G + ++ Y  LD        F +DP +GV
Sbjct: 152 LGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP----FFSVDPQTGV 207

Query: 639 IRTN-KALDRESVATH--DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695
           +RT    +DRE+       ++A  + G     S +  V + + D+ND+PP F      F 
Sbjct: 208 VRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFS 267

Query: 696 ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLET-RQGSDKAELVTMVDL 754
           + E +  GT +G +RA DPD G NA++ YSI  G+ S +FS+ T  QG D   L     L
Sbjct: 268 VVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRD-GLLTVRKPL 326

Query: 755 DYESPRKKYELVIRAAS 771
           D+ES R  Y   + A +
Sbjct: 327 DFESQR-SYSFRVEATN 342



 Score =  111 bits (266), Expect = 4e-22
 Identities = 99/354 (27%), Positives = 171/354 (48%), Gaps = 42/354 (11%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVTA 67
           I V D ND+ P+F +  Y A+V E ++ GT+V+ + A D D    G +A++ YT+     
Sbjct: 138 IKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTV----L 193

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRA-SLDREKVARYTVLVKATDQASPV 126
           D L                   F +D ++G + T   ++DRE    + V+++A D    +
Sbjct: 194 DGL-----------------PFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHM 236

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
              LS + T+ V + D NDN P+F +  Y  SV E  +     ++ +++A D D+G N+ 
Sbjct: 237 GG-LSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVE--TAGPGTLVGRLRAQDPDLGDNAL 293

Query: 187 IRYAIIGGNTQMQFSIDS-LSGDVSLV---KTLDYEQVRSYRLVIRAQDGG-SPS--RSN 239
           + Y+I+ G     FSI + L G   L+   K LD+E  RSY   + A +    P+  R  
Sbjct: 294 MAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRG 353

Query: 240 TTQLLINIRDVNDNAPR---FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
             + + ++R    +AP    F  + +  +V EN   G  + ++ A D D   +  + Y++
Sbjct: 354 PFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPASP-IRYSI 412

Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350
                  + +   +I P  G ++T+  LDRE +A + L V AT+ G+  R+  A
Sbjct: 413 LPHS---DPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGEDSRAHKA 463



 Score = 84.6 bits (200), Expect = 4e-14
 Identities = 75/244 (30%), Positives = 121/244 (49%), Gaps = 21/244 (8%)

Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT- 664
           +D D G  GR  Y L  +      FVID A+G I   K+LDRE  A + L A A+D  + 
Sbjct: 70  SDVDRG-EGRTKYLLTGEGAGT-VFVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASN 127

Query: 665 -PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE---GPNA 720
            P +  +  + IK++DIND+PP+F        + E S +GT++ ++ AHD D+   G +A
Sbjct: 128 RPLEPPSEFI-IKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSA 186

Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP-----LW 775
            + Y++  G     FS++ + G  +  +  M   D E+ ++++ +VI+A         L 
Sbjct: 187 KLVYTVLDG--LPFFSVDPQTGVVRTAIPNM---DRET-QEEFLVVIQAKDMGGHMGGLS 240

Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILS 833
               V + ++DVNDN P        F+  +   P    GR+ A D D+ D   + Y IL 
Sbjct: 241 GSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILD 300

Query: 834 GNNA 837
           G  +
Sbjct: 301 GEGS 304


>UniRef50_P55290 Cluster: Cadherin-13 precursor; n=40;
           Euteleostomi|Rep: Cadherin-13 precursor - Homo sapiens
           (Human)
          Length = 713

 Score =  153 bits (372), Expect = 5e-35
 Identities = 147/533 (27%), Positives = 230/533 (43%), Gaps = 44/533 (8%)

Query: 175 KATDADVGANSAIRYAIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232
           K  D+D    S  R    G + + +  F I+  +G VS+ +TLD E +  Y+L +   D 
Sbjct: 161 KVVDSDRPERSKFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDV 220

Query: 233 GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV--NA 290
              +      L + + D NDN P F    +   V E  P G +++R+ A+DAD+    NA
Sbjct: 221 NGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNA 280

Query: 291 ELTYTMTDKDYTGNVDLPITIDPRSGWVYT---SGQLDRET--QAKYQLLVTATD--GGD 343
            L Y +  +           IDP  G + T      LDRET    KY+L++ A D  G D
Sbjct: 281 LLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLD 340

Query: 344 PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN----RL 399
              + TAT              F   +++  + E+   G  +V LT  D D+      R 
Sbjct: 341 VGLTGTATATIMIDDKNDHSPKFTKKEFQATV-EEGAVGV-IVNLTVEDKDDPTTGAWRA 398

Query: 400 HYEITGGNTRGRFSI--TSQNGRGLITVAQPLDFKQERRYVLTVSATD--------SGGR 449
            Y I  GN    F I    Q   G+++V +PLD++    + L +   +        S G 
Sbjct: 399 AYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGP 458

Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509
           S TA V I + D N   PVF   P   +  ED  +G+ +L V+ATD D   +  I YS+ 
Sbjct: 459 SSTATVHITVLDVNE-GPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVY 517

Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRET----MSGYLLTVTARDGGVPSLSDTT 565
            + +            INP  G + T  +LDRE+     S Y     A D G P  + T 
Sbjct: 518 KDPAG--------WLNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPATGTG 569

Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN-GRIHYELDPKD 624
            + I++ DVNDN P     +  A + +DA    SV  +GA+D D+  N     +E+  + 
Sbjct: 570 TLLITLEDVNDNAPFIYPTV--AEVCDDA-KNLSVVILGASDKDLHPNTDPFKFEIHKQA 626

Query: 625 REEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
             +  + I   +        L   + A ++L  +  D G PP ++   + +++
Sbjct: 627 VPDKVWKISKINNTHALVSLLQNLNKANYNLPIMVTDSGKPPMTNITDLRVQV 679



 Score =  125 bits (302), Expect = 2e-26
 Identities = 136/478 (28%), Positives = 214/478 (44%), Gaps = 60/478 (12%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD--IGKNAEVEYTIELVTA 67
           ++ V+D ND+ P+F    Y   V EG+ +GTTV+ + A D D     NA + Y I   T 
Sbjct: 232 EVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTP 291

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS---LDREKV--ARYTVLVKATDQ 122
           D  +P               ++F ID   G ++T  S   LDRE +   +Y ++++A D 
Sbjct: 292 DKPSP---------------NMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDM 336

Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182
           A  +   L+ TAT  + I D ND+ P+F++K +  +V+E        VI  +   D D  
Sbjct: 337 AG-LDVGLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGAV----GVIVNLTVEDKDDP 391

Query: 183 ANSAIR--YAIIGGNTQMQFSI----DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG--- 233
              A R  Y II GN    F I     +  G +S+VK LDYE    + L+I+ ++     
Sbjct: 392 TTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLV 451

Query: 234 ---SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290
              S   S+T  + I + DVN+  P FY      +  E++ +G  ++ V A D D   + 
Sbjct: 452 PDVSYGPSSTATVHITVLDVNE-GPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQ 510

Query: 291 ELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET----QAKYQLLVTATDGGDPPR 346
            + Y++  KD  G     + I+P +G V T+  LDRE+     + Y  L  A D G+PP 
Sbjct: 511 TIRYSVY-KDPAG----WLNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPA 565

Query: 347 SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEI 403
           + T T                P   EV    D+     VV L A+D D     +   +EI
Sbjct: 566 TGTGTLLITLEDVNDNAPFIYPTVAEV---CDDAKNLSVVILGASDKDLHPNTDPFKFEI 622

Query: 404 TGGNTRGR-FSITS-QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINI 459
                  + + I+   N   L+++ Q L+   +  Y L +  TDSG    T +  + +
Sbjct: 623 HKQAVPDKVWKISKINNTHALVSLLQNLN---KANYNLPIMVTDSGKPPMTNITDLRV 677



 Score =  123 bits (296), Expect = 8e-26
 Identities = 127/434 (29%), Positives = 196/434 (45%), Gaps = 47/434 (10%)

Query: 392 DADEDNRLHYEITGGNT----RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447
           D+D   R  + +TG       +G F I    G   ++V + LD +    Y L V  TD  
Sbjct: 164 DSDRPERSKFRLTGKGVDQEPKGIFRINENTGS--VSVTRTLDREVIAVYQLFVETTDVN 221

Query: 448 GRSDTAMV--QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD--VGINAQ 503
           G++    V  ++ + D N+  P+F   PY   V E +P GTTV+ ++A D+D     NA 
Sbjct: 222 GKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNAL 281

Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITT---NKLLDRETMSG--YLLTVTARD--G 556
           + Y++  +  ++   +    F I+P+ G I T     LLDRET+    Y L + A+D  G
Sbjct: 282 LRYNIRQQTPDKPSPN---MFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAG 338

Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG-- 614
               L+ T    I + D ND+ P F ++ + A + E A VG  V+ +   D D    G  
Sbjct: 339 LDVGLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGA-VGVIVN-LTVEDKDDPTTGAW 396

Query: 615 RIHYEL---DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP--PQ-- 667
           R  Y +   +P    E         G++   K LD E  A H L  + ++   P  P   
Sbjct: 397 RAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTL-LIKVENEDPLVPDVS 455

Query: 668 ---SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724
              SST  VHI + D+N+ P VF  D +     E+  +G+ +  + A DPD   +  + Y
Sbjct: 456 YGPSSTATVHITVLDVNEGP-VFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRY 514

Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP---RKKYE---LVIRAASPPLWNDV 778
           S+   D +   ++    G+    + T   LD ESP      Y    L I + +PP     
Sbjct: 515 SVYK-DPAGWLNINPINGT----VDTTAVLDRESPFVDNSVYTALFLAIDSGNPPATGTG 569

Query: 779 RVEILVTDVNDNAP 792
            + I + DVNDNAP
Sbjct: 570 TLLITLEDVNDNAP 583



 Score =  118 bits (285), Expect = 2e-24
 Identities = 123/404 (30%), Positives = 175/404 (43%), Gaps = 39/404 (9%)

Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
           I+  +G V  +  LDRE  A YQL V  TD                         F  G 
Sbjct: 190 INENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGP 249

Query: 371 YEVELAEDEPPGTPVVTLTATDADE---DNRL-HYEITGGN----TRGRFSITSQNGRGL 422
           Y   + E  P GT V+ +TA DAD+   DN L  Y I        +   F I  + G  +
Sbjct: 250 YIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKG-DI 308

Query: 423 ITVAQPLDFKQER----RYVLTVSATDSGGR----SDTAMVQINITDANNYAPVFENAPY 474
           +TV  P    +E     +Y L + A D  G     + TA   I I D N+++P F    +
Sbjct: 309 VTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEF 368

Query: 475 TASVFEDAPIGTTV-LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT--G 531
            A+V E+  +G  V L V   D       +  Y++ +    ++   H      NPQT  G
Sbjct: 369 QATV-EEGAVGVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHT-----NPQTNEG 422

Query: 532 AITTNKLLDRETMSGY--LLTVTARDGGVPSLS----DTTDVEISVVDVNDNEPVFKQQL 585
            ++  K LD E  + +  L+ V   D  VP +S     T  V I+V+DVN+  PVF    
Sbjct: 423 MLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVNEG-PVFYPDP 481

Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645
                 ED  VG+ +  V ATD D   +  I Y +  KD   G   I+P +G + T   L
Sbjct: 482 MMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVY-KD-PAGWLNINPINGTVDTTAVL 539

Query: 646 DRESV----ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685
           DRES     + +    +AID G PP + T  + I +ED+ND+ P
Sbjct: 540 DRESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAP 583



 Score =  116 bits (279), Expect = 9e-24
 Identities = 142/518 (27%), Positives = 218/518 (42%), Gaps = 46/518 (8%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           +FRI+  +G++    +LDRE +A Y + V+ TD        L     + V +ID NDN P
Sbjct: 187 IFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKT---LEGPVPLEVIVIDQNDNRP 243

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA--NSAIRYAIIGGN----TQMQFSI 202
            F E  Y   V E  S T   V+ ++ A DAD  A  N+ +RY I        +   F I
Sbjct: 244 IFREGPYIGHVMEG-SPTGTTVM-RMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYI 301

Query: 203 DSLSGDVSLVKT---LDYEQVRS--YRLVIRAQD--GGSPSRSNTTQLLINIRDVNDNAP 255
           D   GD+  V +   LD E + +  Y L+I AQD  G     + T    I I D ND++P
Sbjct: 302 DPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSP 361

Query: 256 RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA--ELTYTMTDKDYTGNVDLPITIDP 313
           +F    FQ +V E   +G  IV +   D D+         YT+ + +   + ++      
Sbjct: 362 KFTKKEFQATVEEGA-VGV-IVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQT 419

Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDP-------PRSATATXXXXXXXXXXXXXXF 366
             G +     LD E  A + LL+   +  DP         S+TAT              F
Sbjct: 420 NEGMLSVVKPLDYEISAFHTLLI-KVENEDPLVPDVSYGPSSTAT-VHITVLDVNEGPVF 477

Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLIT 424
            P    V   ED   G+ ++T+ ATD D  +   + Y +   +  G  +I   NG    T
Sbjct: 478 YPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVY-KDPAGWLNINPINGTVDTT 536

Query: 425 VA--QPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480
               +   F     Y     A DSG    + T  + I + D N+ AP     P  A V +
Sbjct: 537 AVLDRESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFI--YPTVAEVCD 594

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540
           DA    +V+++ A+D D+  N   T     EI  +AV   D+ + I+          LL 
Sbjct: 595 DAK-NLSVVILGASDKDLHPN---TDPFKFEIHKQAVP--DKVWKISKINNTHALVSLLQ 648

Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578
               + Y L +   D G P +++ TD+ + V    +++
Sbjct: 649 NLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSCRNSK 686



 Score = 94.7 bits (225), Expect = 3e-17
 Identities = 97/361 (26%), Positives = 152/361 (42%), Gaps = 28/361 (7%)

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583
           F IN  TG+++  + LDRE ++ Y L V   D    +L     +E+ V+D NDN P+F++
Sbjct: 188 FRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFRE 247

Query: 584 QLYTANIMEDALVGTSVSQVGATDAD--VGLNGRIHYEL---DPKDREEGSFVIDPASGV 638
             Y  ++ME +  GT+V ++ A DAD     N  + Y +    P       F IDP  G 
Sbjct: 248 GPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGD 307

Query: 639 IRT---NKALDRESVAT--HDLKAVAID--GGTPPQSSTVIVHIKIEDINDSPPVFESDC 691
           I T      LDRE++    ++L   A D  G     + T    I I+D ND  P F    
Sbjct: 308 IVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKE 367

Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAV--VHYSIKGGDDSNSFSLETRQGSDKAELV 749
               + E + +G  +  +   D D+         Y+I  G+   SF + T   +++  L 
Sbjct: 368 FQATVEEGA-VGVIV-NLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLS 425

Query: 750 TMVDLDYESPRKKYELVIRAASPPLWNDV--------RVEILVTDVNDNAPVMKDFQIIF 801
            +  LDYE       L+      PL  DV         V I V DVN+  PV     ++ 
Sbjct: 426 VVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVNE-GPVFYPDPMMV 484

Query: 802 NNYKDCFPVGPFGRVPAYDADVT--DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNV 859
              +D         V A D D      ++Y +   + A  + +N   G++  +  L+   
Sbjct: 485 TRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYK-DPAGWLNINPINGTVDTTAVLDRES 543

Query: 860 P 860
           P
Sbjct: 544 P 544



 Score = 68.1 bits (159), Expect = 3e-09
 Identities = 55/190 (28%), Positives = 89/190 (46%), Gaps = 16/190 (8%)

Query: 624 DRE-EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND 682
           D+E +G F I+  +G +   + LDRE +A + L     D         V + + + D ND
Sbjct: 181 DQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQND 240

Query: 683 SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE--GPNAVVHYSIK----GGDDSNSFS 736
           + P+F       ++ E SP GTT+  + A D D+    NA++ Y+I+         N F 
Sbjct: 241 NRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFY 300

Query: 737 LETRQGSDKAELVTMVDLDYES-PRKKYELVIRAASPP-----LWNDVRVEILVTDVNDN 790
           ++  +G D   +V+   LD E+    KYEL+I A         L       I++ D ND+
Sbjct: 301 IDPEKG-DIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDH 359

Query: 791 AP--VMKDFQ 798
           +P    K+FQ
Sbjct: 360 SPKFTKKEFQ 369


>UniRef50_Q4SS36 Cluster: Chromosome 11 SCAF14479, whole genome
           shotgun sequence; n=2; Euteleostomi|Rep: Chromosome 11
           SCAF14479, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 908

 Score =  153 bits (371), Expect = 7e-35
 Identities = 154/525 (29%), Positives = 234/525 (44%), Gaps = 51/525 (9%)

Query: 178 DADVGANSAIRYAIIGGNTQMQ----FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233
           D DVG    IRY+I G          ++ID +SG++ + + LD E   S+ L   A D  
Sbjct: 223 DKDVG----IRYSITGAGADQPPSGIYNIDPISGNMFVTQPLDREDRASFHLRAHAVDMN 278

Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG--VNAE 291
                N  +L I + D+NDN P F   ++  SV+E    G S+++V A D+D+    N  
Sbjct: 279 GNQVENPIELYIYVIDMNDNRPEFQNQVYNGSVAEGSKPGSSVMQVTATDSDDSTTANGM 338

Query: 292 LTYTMTDKDYTGNVDLPITIDPRSGWVYT-SGQLDRETQAKYQLLVTATD--GG-DPPRS 347
           + Y +  +     +    TI+  +G + T S  LDRE  ++Y ++V ATD  G  +   S
Sbjct: 339 VRYRILSQTPHNPIPNMFTINSETGDIVTVSAGLDREKVSQYTIIVQATDMEGNLNFGLS 398

Query: 348 ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH----YEI 403
            TAT                   +  E+ E++     V  LT  D D+ +  +    Y I
Sbjct: 399 NTATALISITDINDNPPELTVRTFSGEVPENK-VNVVVTNLTVVDRDQPHSPNWNAVYRI 457

Query: 404 TGGNTRGRFSITSQ--NGRGLITVAQPLDFKQERRYVLTVSATD-----SGGRS---DTA 453
            GG+  G F+I +      G++TV +P+DF+  R + LTV  ++     SG +S    TA
Sbjct: 458 VGGDPTGHFTIHTNPITNEGMLTVIKPVDFEMNRAFGLTVVVSNQAHLASGIQSSLQSTA 517

Query: 454 MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513
            V I++ D N   PVF   P      E  P GTT+ V +A D D  I+  + YS  S+ +
Sbjct: 518 GVTISVQDVNE-PPVFPVNPKMIRFEEGVPAGTTLTVFAAQDPDRFIHQIVRYSKLSDPA 576

Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETM----SGYLLTVTARD---GGVPSLSDTTD 566
           N           IN   G ITT  LLDRE+M    + Y  T  A D    G P  S T  
Sbjct: 577 N--------WLKINRTNGQITTMALLDRESMFVKNNVYEATFLAFDNGKSGSPPASGTGT 628

Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN-GRIHYELDPKDR 625
           ++I ++DVNDN P    +   A + +     + ++ + A D D   N G   +EL     
Sbjct: 629 LQIYLIDVNDNAPELIPR--EAQLCDRPRPNSRIN-ITAADGDADPNVGPFVFELPSFPA 685

Query: 626 E-EGSFVIDPASG-VIRTNKALDRESVATHDLKAVAIDGGTPPQS 668
               ++ I   +G   +    L       +D+  +  D G PP S
Sbjct: 686 SVRRNWTISRLNGDYAQLKLRLSYLEAGVYDIPVIVSDSGNPPLS 730



 Score =  137 bits (331), Expect = 5e-30
 Identities = 132/435 (30%), Positives = 195/435 (44%), Gaps = 46/435 (10%)

Query: 391 TDADEDNRLHYEITGGNT----RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446
           +D D+D  + Y ITG        G ++I   +G   +T  QPLD +    + L   A D 
Sbjct: 220 SDQDKDVGIRYSITGAGADQPPSGIYNIDPISGNMFVT--QPLDREDRASFHLRAHAVDM 277

Query: 447 GGRSDTAMVQ--INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD--VGINA 502
            G      ++  I + D N+  P F+N  Y  SV E +  G++V+ V+ATDSD     N 
Sbjct: 278 NGNQVENPIELYIYVIDMNDNRPEFQNQVYNGSVAEGSKPGSSVMQVTATDSDDSTTANG 337

Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL-LDRETMSGYLLTVTARD--GGVP 559
            + Y + S+  +  + +    F IN +TG I T    LDRE +S Y + V A D  G + 
Sbjct: 338 MVRYRILSQTPHNPIPN---MFTINSETGDIVTVSAGLDREKVSQYTIIVQATDMEGNLN 394

Query: 560 -SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV--GLNGRI 616
             LS+T    IS+ D+NDN P    + ++  + E+  V   V+ +   D D     N   
Sbjct: 395 FGLSNTATALISITDINDNPPELTVRTFSGEVPENK-VNVVVTNLTVVDRDQPHSPNWNA 453

Query: 617 HYELDPKDREEGSFVI--DPAS--GVIRTNKALDRESVATHDLKAVAID------GGTPP 666
            Y +   D   G F I  +P +  G++   K +D E      L  V  +      G    
Sbjct: 454 VYRIVGGD-PTGHFTIHTNPITNEGMLTVIKPVDFEMNRAFGLTVVVSNQAHLASGIQSS 512

Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726
             ST  V I ++D+N+ PPVF  +       E  P GTT+    A DPD   + +V YS 
Sbjct: 513 LQSTAGVTISVQDVNE-PPVFPVNPKMIRFEEGVPAGTTLTVFAAQDPDRFIHQIVRYS- 570

Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK---YELVI------RAASPPLWND 777
           K  D +N   +    G    ++ TM  LD ES   K   YE         ++ SPP    
Sbjct: 571 KLSDPANWLKINRTNG----QITTMALLDRESMFVKNNVYEATFLAFDNGKSGSPPASGT 626

Query: 778 VRVEILVTDVNDNAP 792
             ++I + DVNDNAP
Sbjct: 627 GTLQIYLIDVNDNAP 641



 Score =  132 bits (319), Expect = 1e-28
 Identities = 125/466 (26%), Positives = 209/466 (44%), Gaps = 51/466 (10%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           I   I V+D ND+ P F+ Q Y  SV EG+  G++V+ + ATD D    A       +++
Sbjct: 286 IELYIYVIDMNDNRPEFQNQVYNGSVAEGSKPGSSVMQVTATDSDDSTTANGMVRYRILS 345

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLT-RASLDREKVARYTVLVKATDQASP 125
               NP             + ++F I+  +G ++T  A LDREKV++YT++V+ATD    
Sbjct: 346 QTPHNP-------------IPNMFTINSETGDIVTVSAGLDREKVSQYTIIVQATDMEGN 392

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV--GA 183
           ++  LS+TAT  ++I D NDN P+ + +T++  V E+     N V+  +   D D     
Sbjct: 393 LNFGLSNTATALISITDINDNPPELTVRTFSGEVPEN---KVNVVVTNLTVVDRDQPHSP 449

Query: 184 NSAIRYAIIGGNTQMQFSID----SLSGDVSLVKTLDYEQVRSYRLVI------RAQDGG 233
           N    Y I+GG+    F+I     +  G ++++K +D+E  R++ L +          G 
Sbjct: 450 NWNAVYRIVGGDPTGHFTIHTNPITNEGMLTVIKPVDFEMNRAFGLTVVVSNQAHLASGI 509

Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293
             S  +T  + I+++DVN+  P F  +       E VP G ++    A D D  ++  + 
Sbjct: 510 QSSLQSTAGVTISVQDVNE-PPVFPVNPKMIRFEEGVPAGTTLTVFAAQDPDRFIHQIVR 568

Query: 294 YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET----QAKYQLLVTATD---GGDPPR 346
           Y+             + I+  +G + T   LDRE+       Y+    A D    G PP 
Sbjct: 569 YSKLSDPANW-----LKINRTNGQITTMALLDRESMFVKNNVYEATFLAFDNGKSGSPPA 623

Query: 347 SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH---YEI 403
           S T T               +P   E +L  D P     + +TA D D D  +    +E+
Sbjct: 624 SGTGTLQIYLIDVNDNAPELIP--REAQLC-DRPRPNSRINITAADGDADPNVGPFVFEL 680

Query: 404 TG--GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447
                + R  ++I+  NG     +   L + +   Y + V  +DSG
Sbjct: 681 PSFPASVRRNWTISRLNG-DYAQLKLRLSYLEAGVYDIPVIVSDSG 725



 Score =  107 bits (256), Expect = 6e-21
 Identities = 104/385 (27%), Positives = 179/385 (46%), Gaps = 33/385 (8%)

Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547
           V + S  D DVGI   IT + + +  +         + I+P +G +   + LDRE  + +
Sbjct: 216 VRIRSDQDKDVGIRYSITGAGADQPPSGI-------YNIDPISGNMFVTQPLDREDRASF 268

Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607
            L   A D     + +  ++ I V+D+NDN P F+ Q+Y  ++ E +  G+SV QV ATD
Sbjct: 269 HLRAHAVDMNGNQVENPIELYIYVIDMNDNRPEFQNQVYNGSVAEGSKPGSSVMQVTATD 328

Query: 608 AD--VGLNGRIHYEL---DPKDREEGSFVIDPASG-VIRTNKALDRESVATHDL--KAVA 659
           +D     NG + Y +    P +     F I+  +G ++  +  LDRE V+ + +  +A  
Sbjct: 329 SDDSTTANGMVRYRILSQTPHNPIPNMFTINSETGDIVTVSAGLDREKVSQYTIIVQATD 388

Query: 660 IDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE-- 716
           ++G      S+T    I I DIND+PP       +  + EN  +   +  +   D D+  
Sbjct: 389 MEGNLNFGLSNTATALISITDINDNPPELTVRTFSGEVPENK-VNVVVTNLTVVDRDQPH 447

Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN 776
            PN    Y I GGD +  F++ T   +++  L  +  +D+E  R     V+ +    L +
Sbjct: 448 SPNWNAVYRIVGGDPTGHFTIHTNPITNEGMLTVIKPVDFEMNRAFGLTVVVSNQAHLAS 507

Query: 777 DVR--------VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRV-PAYDAD--VTD 825
            ++        V I V DVN+      + ++I   +++  P G    V  A D D  +  
Sbjct: 508 GIQSSLQSTAGVTISVQDVNEPPVFPVNPKMI--RFEEGVPAGTTLTVFAAQDPDRFIHQ 565

Query: 826 KLQYRILSGNNANLILLNETTGSMT 850
            ++Y  LS + AN + +N T G +T
Sbjct: 566 IVRYSKLS-DPANWLKINRTNGQIT 589



 Score = 99.5 bits (237), Expect = 1e-18
 Identities = 115/442 (26%), Positives = 179/442 (40%), Gaps = 42/442 (9%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           ++ ID  SG +     LDRE  A + +   A D      +++ +   +++ +ID NDN P
Sbjct: 244 IYNIDPISGNMFVTQPLDREDRASFHLRAHAVDMNG---NQVENPIELYIYVIDMNDNRP 300

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDAD--VGANSAIRYAIIGGNTQ----MQFSI 202
           +F  + Y  SV E      +  + ++ ATD+D    AN  +RY I+           F+I
Sbjct: 301 EFQNQVYNGSVAEGSKPGSS--VMQVTATDSDDSTTANGMVRYRILSQTPHNPIPNMFTI 358

Query: 203 DSLSGDVSLVKT-LDYEQVRSYRLVIRAQD--GG-SPSRSNTTQLLINIRDVNDNAPRFY 258
           +S +GD+  V   LD E+V  Y ++++A D  G  +   SNT   LI+I D+NDN P   
Sbjct: 359 NSETGDIVTVSAGLDREKVSQYTIIVQATDMEGNLNFGLSNTATALISITDINDNPPELT 418

Query: 259 TSLFQESVSEN-VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317
              F   V EN V +  + + V   D     N    Y +   D TG+  +        G 
Sbjct: 419 VRTFSGEVPENKVNVVVTNLTVVDRDQPHSPNWNAVYRIVGGDPTGHFTIHTNPITNEGM 478

Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV---- 373
           +     +D E    + L V  ++         ++                P  + V    
Sbjct: 479 LTVIKPVDFEMNRAFGLTVVVSNQAHLASGIQSSLQSTAGVTISVQDVNEPPVFPVNPKM 538

Query: 374 -ELAEDEPPGTPVVTLTATDADEDNRLHYEITG----GNTRGRFSITSQNGRGLITVAQP 428
               E  P GT   TLT   A + +R  ++I       +      I   NG+  IT    
Sbjct: 539 IRFEEGVPAGT---TLTVFAAQDPDRFIHQIVRYSKLSDPANWLKINRTNGQ--ITTMAL 593

Query: 429 LD----FKQERRYVLTVSATDSG-----GRSDTAMVQINITDANNYAPVFENAPYTASVF 479
           LD    F +   Y  T  A D+G       S T  +QI + D N+ AP  E  P  A + 
Sbjct: 594 LDRESMFVKNNVYEATFLAFDNGKSGSPPASGTGTLQIYLIDVNDNAP--ELIPREAQLC 651

Query: 480 EDAPIGTTVLVVSATDSDVGIN 501
            D P   + + ++A D D   N
Sbjct: 652 -DRPRPNSRINITAADGDADPN 672


>UniRef50_A7RRZ9 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 550

 Score =  151 bits (367), Expect = 2e-34
 Identities = 137/507 (27%), Positives = 223/507 (43%), Gaps = 44/507 (8%)

Query: 89  VFRIDGRSGALLTRASLDREKVAR------YTVLVKATDQASPVSDRLSSTATIHVNIID 142
           +F I+  +G L T+  L+REK+        + + +K T     VS    +T    V ++D
Sbjct: 64  IFEINAATGVLRTKILLNREKLPPSAQGDIFQIQIKVTTDTGGVS----ATIPTEVRVLD 119

Query: 143 DNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI 202
            ND+ P+F +    + + E  S  +       +A DAD+G NS   Y I+ GN    FS+
Sbjct: 120 INDHSPKFPQDFEELQISE--SAPERSKFPLQRALDADIGNNSIQEYRIVRGNEDGLFSL 177

Query: 203 D--SLSGDVSLV-----KTLDYEQVRSYRLVIRAQDGGSP-SRSNTTQLLINIRDVNDNA 254
                S D+  V     K LD E    Y+LVI A DGG P  RS   ++ I I D ND++
Sbjct: 178 SLKRFSPDMIYVYLVNTKRLDRETRDFYQLVIVAVDGGFPLPRSGRKEVNITILDSNDHS 237

Query: 255 PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR 314
           P F    +  SV EN P G  ++RV A D D G N E+ + + +    G       +D  
Sbjct: 238 PEFSKDFYTASVPENAPNGTYLLRVTAIDQDIGKNGEIMFYLDESPERG----LFRMDEY 293

Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGGD---PPRS-ATATXXXXXXXXXXXXXXFMPGQ 370
           +G ++T+  LD E +++Y+L V A D G    P R+  T                 +P  
Sbjct: 294 TGEIWTNAVLDYEVKSEYRLTVVAQDQGPDSIPVRAQVTIKDKNDNAPTIQVKLLQVPNA 353

Query: 371 YEVELA-EDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITS-QNGRGLITVA 426
               L  ED   G+ V  +   D D    ++   ++T  + +  F++    N    + V 
Sbjct: 354 ARPGLVPEDITTGSNVAIVEVRDRDSSLTVNSVVDVTLLHHKHDFALRRIFNTFYNLEVQ 413

Query: 427 QPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
           +PL+  ++  Y +   A D G         + ++I D N + P +       ++ ++   
Sbjct: 414 RPLNLTRQSIYKIDFIARDRGVPTLETNNSLTLHIEDKNRHTPTYPTPSRDITIIDNTQP 473

Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
           G  V+ + ATD D G+N +I YSL          + D+ F+++   G +    + +    
Sbjct: 474 GDEVVTIRATDPDSGLNGKIQYSL-------IAGNDDKTFILDKDRGELV---VFNYMFQ 523

Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISV 571
           S Y+LT+ A D G P       + I V
Sbjct: 524 SSYVLTIKASDSGNPPSESLVRIRIRV 550



 Score =  151 bits (365), Expect = 4e-34
 Identities = 124/463 (26%), Positives = 198/463 (42%), Gaps = 31/463 (6%)

Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290
           D G  S +  T+  + + D+ND++P+F     +  +SE+ P        +A DAD G N+
Sbjct: 103 DTGGVSATIPTE--VRVLDINDHSPKFPQDFEELQISESAPERSKFPLQRALDADIGNNS 160

Query: 291 ELTYTMTDKDYTGNVDLPIT-IDPRSGWVY--TSGQLDRETQAKYQLLVTATDGGDP-PR 346
              Y +   +  G   L +    P   +VY   + +LDRET+  YQL++ A DGG P PR
Sbjct: 161 IQEYRIVRGNEDGLFSLSLKRFSPDMIYVYLVNTKRLDRETRDFYQLVIVAVDGGFPLPR 220

Query: 347 SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEIT 404
           S                  F    Y   + E+ P GT ++ +TA D D  ++  + + + 
Sbjct: 221 SGRKEVNITILDSNDHSPEFSKDFYTASVPENAPNGTYLLRVTAIDQDIGKNGEIMFYLD 280

Query: 405 GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANN 464
               RG F +    G   I     LD++ +  Y LTV A D G  S     Q+ I D N+
Sbjct: 281 ESPERGLFRMDEYTGE--IWTNAVLDYEVKSEYRLTVVAQDQGPDSIPVRAQVTIKDKND 338

Query: 465 YAPVFE-------NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517
            AP  +       NA     V ED   G+ V +V   D D  +         + + +  +
Sbjct: 339 NAPTIQVKLLQVPNAARPGLVPEDITTGSNVAIVEVRDRDSSLTV-------NSVVDVTL 391

Query: 518 AHHDQQFVINPQTGA---ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
            HH   F +         +   + L+    S Y +   ARD GVP+L     + + + D 
Sbjct: 392 LHHKHDFALRRIFNTFYNLEVQRPLNLTRQSIYKIDFIARDRGVPTLETNNSLTLHIEDK 451

Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634
           N + P +        I+++   G  V  + ATD D GLNG+I Y L     ++ +F++D 
Sbjct: 452 NRHTPTYPTPSRDITIIDNTQPGDEVVTIRATDPDSGLNGKIQYSL-IAGNDDKTFILDK 510

Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
             G +     + + S   + L   A D G PP  S V + I++
Sbjct: 511 DRGELVVFNYMFQSS---YVLTIKASDSGNPPSESLVRIRIRV 550



 Score =  141 bits (342), Expect = 2e-31
 Identities = 118/462 (25%), Positives = 192/462 (41%), Gaps = 33/462 (7%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66
           I  ++ VLD NDHSP F     E  + E A   +     +A D DIG N+  EY I    
Sbjct: 111 IPTEVRVLDINDHSPKFPQDFEELQISESAPERSKFPLQRALDADIGNNSIQEYRIVRGN 170

Query: 67  ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126
            D L                 D+  +      L+    LDRE    Y +++ A D   P+
Sbjct: 171 EDGL-------FSLSLKRFSPDMIYV-----YLVNTKRLDRETRDFYQLVIVAVDGGFPL 218

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
               S    +++ I+D ND+ P+FS+  YT SV E+    +   + ++ A D D+G N  
Sbjct: 219 PR--SGRKEVNITILDSNDHSPEFSKDFYTASVPEN--APNGTYLLRVTAIDQDIGKNGE 274

Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246
           I + +     +  F +D  +G++     LDYE    YRL + AQD G  S     Q  + 
Sbjct: 275 IMFYLDESPERGLFRMDEYTGEIWTNAVLDYEVKSEYRLTVVAQDQGPDSIPVRAQ--VT 332

Query: 247 IRDVNDNAPRFYTSLFQES-------VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
           I+D NDNAP     L Q         V E++  G ++  V+  D D  +       +T  
Sbjct: 333 IKDKNDNAPTIQVKLLQVPNAARPGLVPEDITTGSNVAIVEVRDRDSSLTVNSVVDVTLL 392

Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359
            +  +  L    +     +     L+   Q+ Y++   A D G P      +        
Sbjct: 393 HHKHDFALRRIFNTFYN-LEVQRPLNLTRQSIYKIDFIARDRGVPTLETNNSLTLHIEDK 451

Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQ 417
                 +     ++ + ++  PG  VVT+ ATD D   + ++ Y +  GN    F +   
Sbjct: 452 NRHTPTYPTPSRDITIIDNTQPGDEVVTIRATDPDSGLNGKIQYSLIAGNDDKTFILDKD 511

Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINI 459
            G  ++      ++  +  YVLT+ A+DSG     ++V+I I
Sbjct: 512 RGELVV-----FNYMFQSSYVLTIKASDSGNPPSESLVRIRI 548



 Score =  140 bits (340), Expect = 4e-31
 Identities = 138/474 (29%), Positives = 208/474 (43%), Gaps = 42/474 (8%)

Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392
           Q+ VT   GG    SAT                F     E++++E  P  +      A D
Sbjct: 97  QIKVTTDTGGV---SATIPTEVRVLDINDHSPKFPQDFEELQISESAPERSKFPLQRALD 153

Query: 393 ADEDNRL--HYEITGGNTRGRFSITSQN-GRGLITV----AQPLDFKQERRYVLTVSATD 445
           AD  N     Y I  GN  G FS++ +     +I V     + LD +    Y L + A D
Sbjct: 154 ADIGNNSIQEYRIVRGNEDGLFSLSLKRFSPDMIYVYLVNTKRLDRETRDFYQLVIVAVD 213

Query: 446 SG---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502
            G    RS    V I I D+N+++P F    YTASV E+AP GT +L V+A D D+G N 
Sbjct: 214 GGFPLPRSGRKEVNITILDSNDHSPEFSKDFYTASVPENAPNGTYLLRVTAIDQDIGKNG 273

Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562
           +I + L               F ++  TG I TN +LD E  S Y LTV A+D G  S+ 
Sbjct: 274 EIMFYLDESPERGL-------FRMDEYTGEIWTNAVLDYEVKSEYRLTVVAQDQGPDSI- 325

Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTAN-------IMEDALVGTSVSQVGATDADVGL--N 613
                ++++ D NDN P  + +L           + ED   G++V+ V   D D  L  N
Sbjct: 326 -PVRAQVTIKDKNDNAPTIQVKLLQVPNAARPGLVPEDITTGSNVAIVEVRDRDSSLTVN 384

Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673
             +   L     +     I      +   + L+    + + +  +A D G P   +   +
Sbjct: 385 SVVDVTLLHHKHDFALRRIFNTFYNLEVQRPLNLTRQSIYKIDFIARDRGVPTLETNNSL 444

Query: 674 HIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN 733
            + IED N   P + +      I +N+  G  +  IRA DPD G N  + YS+  G+D  
Sbjct: 445 TLHIEDKNRHTPTYPTPSRDITIIDNTQPGDEVVTIRATDPDSGLNGKIQYSLIAGNDDK 504

Query: 734 SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILV 784
           +F L+     D+ ELV + +  ++S    Y L I+A+   +PP  + VR+ I V
Sbjct: 505 TFILD----KDRGELV-VFNYMFQS---SYVLTIKASDSGNPPSESLVRIRIRV 550



 Score =  136 bits (329), Expect = 8e-30
 Identities = 134/503 (26%), Positives = 225/503 (44%), Gaps = 33/503 (6%)

Query: 374 ELAEDEPPGTPVVTLTATDADEDNRL-----HYEITGGNTRGRFSITSQNG--RGLITVA 426
           ++ E++ PG  V  ++ TD  +  RL      Y+I G    G F I +  G  R  I + 
Sbjct: 23  QVKEEQDPGALVGDVSQTDIPKRLRLSFGKIRYQIQGP-ADGIFEINAATGVLRTKILLN 81

Query: 427 Q---PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483
           +   P   + +   +     TD+GG S T   ++ + D N+++P F        + E AP
Sbjct: 82  REKLPPSAQGDIFQIQIKVTTDTGGVSATIPTEVRVLDINDHSPKFPQDFEELQISESAP 141

Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
             +   +  A D+D+G N+   Y +     +   +   ++F  +     +   K LDRET
Sbjct: 142 ERSKFPLQRALDADIGNNSIQEYRIVRGNEDGLFSLSLKRFSPDMIYVYLVNTKRLDRET 201

Query: 544 MSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602
              Y L + A DGG P   S   +V I+++D ND+ P F +  YTA++ E+A  GT + +
Sbjct: 202 RDFYQLVIVAVDGGFPLPRSGRKEVNITILDSNDHSPEFSKDFYTASVPENAPNGTYLLR 261

Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662
           V A D D+G NG I + LD +  E G F +D  +G I TN  LD E  + + L  VA D 
Sbjct: 262 VTAIDQDIGKNGEIMFYLD-ESPERGLFRMDEYTGEIWTNAVLDYEVKSEYRLTVVAQDQ 320

Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTF-------YISENSPIGTTIG--EIRAHD 713
           G  P S  V   + I+D ND+ P  +   L          + E+   G+ +   E+R  D
Sbjct: 321 G--PDSIPVRAQVTIKDKNDNAPTIQVKLLQVPNAARPGLVPEDITTGSNVAIVEVRDRD 378

Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQGSD-KAELVTMVDLDYESPRKKYELVIRAASP 772
                N+VV  ++      + F+L     +    E+   ++L  +S  K   +      P
Sbjct: 379 SSLTVNSVVDVTLL--HHKHDFALRRIFNTFYNLEVQRPLNLTRQSIYKIDFIARDRGVP 436

Query: 773 PLWNDVRVEILVTDVNDNAPVM----KDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQ 828
            L  +  + + + D N + P      +D  II N       V      P  D+ +  K+Q
Sbjct: 437 TLETNNSLTLHIEDKNRHTPTYPTPSRDITIIDNTQPGDEVVTIRATDP--DSGLNGKIQ 494

Query: 829 YRILSGNNANLILLNETTGSMTL 851
           Y +++GN+    +L++  G + +
Sbjct: 495 YSLIAGNDDKTFILDKDRGELVV 517


>UniRef50_UPI0000660AA1 Cluster: Cadherin-7 precursor.; n=1;
           Takifugu rubripes|Rep: Cadherin-7 precursor. - Takifugu
           rubripes
          Length = 784

 Score =  151 bits (365), Expect = 4e-34
 Identities = 170/583 (29%), Positives = 261/583 (44%), Gaps = 79/583 (13%)

Query: 161 EDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV 220
           E+ +  D   + K+ + D D G +  +RY + G      FSID  +GD+   + LD EQ 
Sbjct: 17  EEFTGNDPLYVGKLHS-DVDKG-DGQVRYVLTGEGAASIFSIDESTGDIHATRRLDREQQ 74

Query: 221 RSYRLVIRAQDGGSPSRSNT-TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRV 279
             Y L  +A++  +       +Q +I ++DVNDN P+F    +   V+E  P+G S+V V
Sbjct: 75  AYYTLRAQARNRDTNRLVEPESQFIIKVQDVNDNEPKFLDGPYTARVAERSPVGTSVVTV 134

Query: 280 QAYDADE---GVNAELTYTMTD-KDYTGNVDLPITIDPRSGWVYTS-GQLDRETQAKYQL 334
            A DAD+   G +A L Y++   + Y        +++P++G V T+   LDRE +  + L
Sbjct: 135 VATDADDPTYGNSARLMYSILQGQPY-------FSVEPKTGVVRTALPDLDREVRDSHLL 187

Query: 335 LVTATD--GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392
           +V A D  G     S + +              F    Y+  + E E   T V  + A D
Sbjct: 188 VVQAKDMIGQIGGLSGSTSVTVILTDVNDNPPHFPRRSYQFSVRESELVSTVVAKIRAVD 247

Query: 393 ADE--DNRLHYEITGGNTRGRFSIT--SQNGRGLITVAQPLDFKQERRYVLTVSATD--- 445
            DE  +  L Y I  G+  G FSIT  S    GLIT+ + LDF+ +  Y+L V A++   
Sbjct: 248 PDEGPNAELDYRILDGDGLGIFSITTDSHTQEGLITLHKNLDFETKSSYMLRVEASNLYV 307

Query: 446 ------SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV-----SAT 494
                 SG  SD A V++ + + +   PVF ++     V E A +GT V  V      AT
Sbjct: 308 DARFLSSGPFSDVATVRLLVQNVDE-PPVFHSSVSWMMVSEAAAVGTEVGSVLARDPDAT 366

Query: 495 DSDVGINAQITYSL-----------SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543
           +S + I+A     L           S   S +  ++ ++ F I+  TG ITT + LDRET
Sbjct: 367 NSPIRISADAAPPLTRCWCPNSLGSSCRYSIDRQSNLERYFHIDSGTGVITTAQPLDRET 426

Query: 544 MSGYLLTVTARDGG-----------------------VPSLSDTTDVEISVVDVNDNEPV 580
           ++ + +TV A +                          PSL+    V ISV DVNDN P 
Sbjct: 427 VAVHNITVVATERQHFLAVHSCLFSAWVTSCLVLMPVDPSLTGKAVVLISVTDVNDNPPS 486

Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG-SFVI-----DP 634
                Y   + E++  G  V  + A D D    G+ H+     +  +  SF +     + 
Sbjct: 487 LAID-YDTFVCENSEPGQIVQTLSAVDRDEPEEGQ-HFLFSLSEAGQNLSFTLRDNKDNT 544

Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
           AS + R    L R+ +  H L  V  D   PP SST  + I +
Sbjct: 545 ASILTRPGGFLQRDQL-LHLLPVVISDSSRPPLSSTNTLSITV 586



 Score =  148 bits (359), Expect = 2e-33
 Identities = 110/343 (32%), Positives = 169/343 (49%), Gaps = 28/343 (8%)

Query: 391 TDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR 449
           +D D+ D ++ Y +TG      FSI    G   I   + LD +Q+  Y L   A +    
Sbjct: 32  SDVDKGDGQVRYVLTGEGAASIFSIDESTGD--IHATRRLDREQQAYYTLRAQARNRDTN 89

Query: 450 ---SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506
                 +   I + D N+  P F + PYTA V E +P+GT+V+ V ATD+D       TY
Sbjct: 90  RLVEPESQFIIKVQDVNDNEPKFLDGPYTARVAERSPVGTSVVTVVATDAD-----DPTY 144

Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAI-TTNKLLDRETMSGYLLTVTARD--GGVPSLSD 563
             S+ +   ++      F + P+TG + T    LDRE    +LL V A+D  G +  LS 
Sbjct: 145 GNSARLM-YSILQGQPYFSVEPKTGVVRTALPDLDREVRDSHLLVVQAKDMIGQIGGLSG 203

Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK 623
           +T V + + DVNDN P F ++ Y  ++ E  LV T V+++ A D D G N  + Y +   
Sbjct: 204 STSVTVILTDVNDNPPHFPRRSYQFSVRESELVSTVVAKIRAVDPDEGPNAELDYRILDG 263

Query: 624 DREEGSFVIDPAS----GVIRTNKALDRESVATHDLKAVA----IDG---GTPPQSSTVI 672
           D   G F I   S    G+I  +K LD E+ +++ L+  A    +D     + P S    
Sbjct: 264 D-GLGIFSITTDSHTQEGLITLHKNLDFETKSSYMLRVEASNLYVDARFLSSGPFSDVAT 322

Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
           V + ++++ D PPVF S      +SE + +GT +G + A DPD
Sbjct: 323 VRLLVQNV-DEPPVFHSSVSWMMVSEAAAVGTEVGSVLARDPD 364



 Score =  140 bits (340), Expect = 4e-31
 Identities = 154/533 (28%), Positives = 222/533 (41%), Gaps = 81/533 (15%)

Query: 283 DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG 342
           D D+G + ++ Y +T +   G   +  +ID  +G ++ + +LDRE QA Y L   A +  
Sbjct: 33  DVDKG-DGQVRYVLTGE---GAASI-FSIDESTGDIHATRRLDREQQAYYTLRAQARNR- 86

Query: 343 DPPR--SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--- 397
           D  R     +               F+ G Y   +AE  P GT VVT+ ATDAD+     
Sbjct: 87  DTNRLVEPESQFIIKVQDVNDNEPKFLDGPYTARVAERSPVGTSVVTVVATDADDPTYGN 146

Query: 398 --RLHYEITGGNTRGRFSITSQNGRGLITVAQP-LDFKQERRYVLTVSATDS----GGRS 450
             RL Y I  G     FS+  + G  ++  A P LD +    ++L V A D     GG S
Sbjct: 147 SARLMYSILQGQPY--FSVEPKTG--VVRTALPDLDREVRDSHLLVVQAKDMIGQIGGLS 202

Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510
            +  V + +TD N+  P F    Y  SV E   + T V  + A D D G NA++ Y +  
Sbjct: 203 GSTSVTVILTDVNDNPPHFPRRSYQFSVRESELVSTVVAKIRAVDPDEGPNAELDYRI-- 260

Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS-------LSD 563
            +  + +         + Q G IT +K LD ET S Y+L V A +  V +        SD
Sbjct: 261 -LDGDGLGIFSITTDSHTQEGLITLHKNLDFETKSSYMLRVEASNLYVDARFLSSGPFSD 319

Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV------------- 610
              V + V +V D  PVF   +    + E A VGT V  V A D D              
Sbjct: 320 VATVRLLVQNV-DEPPVFHSSVSWMMVSEAAAVGTEVGSVLARDPDATNSPIRISADAAP 378

Query: 611 ---------GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661
                     L     Y +D +   E  F ID  +GVI T + LDRE+VA H++  VA +
Sbjct: 379 PLTRCWCPNSLGSSCRYSIDRQSNLERYFHIDSGTGVITTAQPLDRETVAVHNITVVATE 438

Query: 662 GG-----------------------TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698
                                     P  +   +V I + D+ND+PP    D  TF + E
Sbjct: 439 RQHFLAVHSCLFSAWVTSCLVLMPVDPSLTGKAVVLISVTDVNDNPPSLAIDYDTF-VCE 497

Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK-AELVT 750
           NS  G  +  + A D DE P    H+     +   + S   R   D  A ++T
Sbjct: 498 NSEPGQIVQTLSAVDRDE-PEEGQHFLFSLSEAGQNLSFTLRDNKDNTASILT 549



 Score =  133 bits (321), Expect = 8e-29
 Identities = 109/320 (34%), Positives = 155/320 (48%), Gaps = 24/320 (7%)

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT-TDVEISVVDVNDNEPVFK 582
           F I+  TG I   + LDRE  + Y L   AR+     L +  +   I V DVNDNEP F 
Sbjct: 54  FSIDESTGDIHATRRLDREQQAYYTLRAQARNRDTNRLVEPESQFIIKVQDVNDNEPKFL 113

Query: 583 QQLYTANIMEDALVGTSVSQVGATDAD---VGLNGRIHYELDPKDREEGSFVIDPASGVI 639
              YTA + E + VGTSV  V ATDAD    G + R+ Y +    + +  F ++P +GV+
Sbjct: 114 DGPYTARVAERSPVGTSVVTVVATDADDPTYGNSARLMYSIL---QGQPYFSVEPKTGVV 170

Query: 640 RTNKA-LDRESVATHDLKAVAID--GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696
           RT    LDRE   +H L   A D  G     S +  V + + D+ND+PP F      F +
Sbjct: 171 RTALPDLDREVRDSHLLVVQAKDMIGQIGGLSGSTSVTVILTDVNDNPPHFPRRSYQFSV 230

Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756
            E+  + T + +IRA DPDEGPNA + Y I  GD    FS+ T   + +  +    +LD+
Sbjct: 231 RESELVSTVVAKIRAVDPDEGPNAELDYRILDGDGLGIFSITTDSHTQEGLITLHKNLDF 290

Query: 757 ESPRKKYELVIRA----------ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKD 806
           E+ +  Y L + A          +S P  +   V +LV +V D  PV     + +    +
Sbjct: 291 ET-KSSYMLRVEASNLYVDARFLSSGPFSDVATVRLLVQNV-DEPPVFHS-SVSWMMVSE 347

Query: 807 CFPVG-PFGRVPAYDADVTD 825
              VG   G V A D D T+
Sbjct: 348 AAAVGTEVGSVLARDPDATN 367



 Score =  113 bits (273), Expect = 5e-23
 Identities = 81/258 (31%), Positives = 133/258 (51%), Gaps = 12/258 (4%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           +F ID  +G +     LDRE+ A YT+  +A ++ +  +  +   +   + + D NDN P
Sbjct: 53  IFSIDESTGDIHATRRLDREQQAYYTLRAQARNRDT--NRLVEPESQFIIKVQDVNDNEP 110

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDAD---VGANSAIRYAIIGGNTQMQFSIDSL 205
           +F +  YT  V E   V  +  +  + ATDAD    G ++ + Y+I+ G  Q  FS++  
Sbjct: 111 KFLDGPYTARVAERSPVGTS--VVTVVATDADDPTYGNSARLMYSILQG--QPYFSVEPK 166

Query: 206 SGDV-SLVKTLDYEQVRSYRLVIRAQD--GGSPSRSNTTQLLINIRDVNDNAPRFYTSLF 262
           +G V + +  LD E   S+ LV++A+D  G     S +T + + + DVNDN P F    +
Sbjct: 167 TGVVRTALPDLDREVRDSHLLVVQAKDMIGQIGGLSGSTSVTVILTDVNDNPPHFPRRSY 226

Query: 263 QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322
           Q SV E+  +   + +++A D DEG NAEL Y + D D  G   +      + G +    
Sbjct: 227 QFSVRESELVSTVVAKIRAVDPDEGPNAELDYRILDGDGLGIFSITTDSHTQEGLITLHK 286

Query: 323 QLDRETQAKYQLLVTATD 340
            LD ET++ Y L V A++
Sbjct: 287 NLDFETKSSYMLRVEASN 304



 Score = 99.1 bits (236), Expect = 2e-18
 Identities = 106/364 (29%), Positives = 167/364 (45%), Gaps = 59/364 (16%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVTA 67
           I V D ND+ P F    Y A V E +  GT+V+T+ ATD D    G +A + Y+I     
Sbjct: 100 IKVQDVNDNEPKFLDGPYTARVAERSPVGTSVVTVVATDADDPTYGNSARLMYSI----- 154

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR-ASLDREKVARYTVLVKATDQASPV 126
                              Q  F ++ ++G + T    LDRE    + ++V+A D    +
Sbjct: 155 ----------------LQGQPYFSVEPKTGVVRTALPDLDREVRDSHLLVVQAKDMIGQI 198

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
              LS + ++ V + D NDN P F  ++Y  SV E   V  + V+AKI+A D D G N+ 
Sbjct: 199 GG-LSGSTSVTVILTDVNDNPPHFPRRSYQFSVRESELV--STVVAKIRAVDPDEGPNAE 255

Query: 187 IRYAIIGGNTQMQFSIDSLS----GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR----- 237
           + Y I+ G+    FSI + S    G ++L K LD+E   SY L + A +    +R     
Sbjct: 256 LDYRILDGDGLGIFSITTDSHTQEGLITLHKNLDFETKSSYMLRVEASNLYVDARFLSSG 315

Query: 238 --SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE-----GVNA 290
             S+   + + +++V D  P F++S+    VSE   +G  +  V A D D       ++A
Sbjct: 316 PFSDVATVRLLVQNV-DEPPVFHSSVSWMMVSEAAAVGTEVGSVLARDPDATNSPIRISA 374

Query: 291 ELTYTMT--------------DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLV 336
           +    +T                D   N++    ID  +G + T+  LDRET A + + V
Sbjct: 375 DAAPPLTRCWCPNSLGSSCRYSIDRQSNLERYFHIDSGTGVITTAQPLDRETVAVHNITV 434

Query: 337 TATD 340
            AT+
Sbjct: 435 VATE 438



 Score = 56.4 bits (130), Expect = 1e-05
 Identities = 89/386 (23%), Positives = 145/386 (37%), Gaps = 66/386 (17%)

Query: 15  DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74
           D ND+ P F  + Y+ SVRE     T V  ++A D D G NAE++Y I       L+ + 
Sbjct: 213 DVNDNPPHFPRRSYQFSVRESELVSTVVAKIRAVDPDEGPNAELDYRI-------LDGDG 265

Query: 75  AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT----DQASPVSDRL 130
                       Q+        G +    +LD E  + Y + V+A+    D     S   
Sbjct: 266 LGIFSITTDSHTQE--------GLITLHKNLDFETKSSYMLRVEASNLYVDARFLSSGPF 317

Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDE--------------DISVTDNPVIAKIKA 176
           S  AT+ + ++ + D  P F      + V E              D   T++P+     A
Sbjct: 318 SDVATVRL-LVQNVDEPPVFHSSVSWMMVSEAAAVGTEVGSVLARDPDATNSPIRISADA 376

Query: 177 TD------ADVGANSAIRYAI-IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA 229
                         S+ RY+I    N +  F IDS +G ++  + LD E V  + + + A
Sbjct: 377 APPLTRCWCPNSLGSSCRYSIDRQSNLERYFHIDSGTGVITTAQPLDRETVAVHNITVVA 436

Query: 230 QDGG-----------------------SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266
            +                          PS +    +LI++ DVNDN P      +   V
Sbjct: 437 TERQHFLAVHSCLFSAWVTSCLVLMPVDPSLTGKAVVLISVTDVNDNPPSLAID-YDTFV 495

Query: 267 SENVPIGYSIVRVQAYDADEGVNAE-LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325
            EN   G  +  + A D DE    +   +++++     +  L    D  +  +   G   
Sbjct: 496 CENSEPGQIVQTLSAVDRDEPEEGQHFLFSLSEAGQNLSFTLRDNKDNTASILTRPGGFL 555

Query: 326 RETQAKYQLLVTATDGGDPPRSATAT 351
           +  Q  + L V  +D   PP S+T T
Sbjct: 556 QRDQLLHLLPVVISDSSRPPLSSTNT 581


>UniRef50_A6E164 Cluster: Large exoprotein; n=2; cellular
            organisms|Rep: Large exoprotein - Roseovarius sp. TM1035
          Length = 5082

 Score =  149 bits (362), Expect = 8e-34
 Identities = 130/434 (29%), Positives = 207/434 (47%), Gaps = 37/434 (8%)

Query: 373  VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432
            V +AED    T + T + TD D  + L Y I+ GN  G F I +  G   +   Q LD +
Sbjct: 2949 VTVAEDLDAATVIATASGTDVDLSDVLSYSISAGNDAGLFEIDATTGDISLVAGQSLDAE 3008

Query: 433  QERRYVLTVSATDSGGRSDTAMVQINITDANN---YAPVFENAPYTASVFEDAPIGTTVL 489
             +  +VLTV+ +D  G +DT  + +N+TD ++    APV  +     SV E+A +GT  +
Sbjct: 3009 TDIEHVLTVTVSDGNGGTDTQEITVNVTDVDDNLTTAPVDADGVAGGSVDENAALGTVGI 3068

Query: 490  VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG--AITTNKLLDRETMSGY 547
              ++TD+D+   A ITY++   +      +    FVI+ +TG  ++ +   +DRET S  
Sbjct: 3069 TAASTDADITSGA-ITYAI---VGGTGATN----FVIDAETGVVSVASGANIDRETGSSL 3120

Query: 548  LLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV-GA 605
             + V A    G  S++ T  + I+ V+  D             + E+A  GT V  V  A
Sbjct: 3121 TIDVQATPANGAASVTSTFTITINDVNEFDVTTPVDSNAAANEVSENAGPGTLVGIVASA 3180

Query: 606  TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL-----DRESVATHDL--KAV 658
            +DAD   NG + Y L   D   G F ID A+G +R + A      D E+  +H +  +A+
Sbjct: 3181 SDADATTNG-VTYSL--TDSAGGIFEIDAATGEVRLSTAAMAPRPDFETAESHTITVQAM 3237

Query: 659  AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
            + DG T  +  T    I I D ND+ PVF  +     ++EN    T++  + A D D   
Sbjct: 3238 SADGSTSTEDFT----ITILDANDTAPVFAINAAQ-SVAENE---TSVVRLSATDVDTDQ 3289

Query: 719  NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP---RKKYELVIRAASPPLW 775
            +  + ++I GGDD  +F +   +G    E V+  D +  +       Y +V+ A      
Sbjct: 3290 SG-ISFTIVGGDDQAAFRVVEDEGVYTLEFVSAPDFEMPTDMGGNNIYNVVVEAFDGTNM 3348

Query: 776  NDVRVEILVTDVND 789
             +    I VTDVN+
Sbjct: 3349 TEQAFAITVTDVNE 3362



 Score =  122 bits (293), Expect = 2e-25
 Identities = 141/516 (27%), Positives = 231/516 (44%), Gaps = 34/516 (6%)

Query: 114  TVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK 173
            T++V  T  A  +S+  S+T T  V I     N    +     V+V ED+      VIA 
Sbjct: 2906 TLVVTYTLTADDLSETDSATDTQTVTITITGTNDSPVASAADGVTVAEDLDAAT--VIAT 2963

Query: 174  IKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLV--KTLDYEQVRSYRLVIRAQD 231
               TD D+  +  + Y+I  GN    F ID+ +GD+SLV  ++LD E    + L +   D
Sbjct: 2964 ASGTDVDL--SDVLSYSISAGNDAGLFEIDATTGDISLVAGQSLDAETDIEHVLTVTVSD 3021

Query: 232  GGSPSRSNTTQLLINIRDVNDN---APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV 288
            G     ++T ++ +N+ DV+DN   AP     +   SV EN  +G   +   + DAD   
Sbjct: 3022 GN--GGTDTQEITVNVTDVDDNLTTAPVDADGVAGGSVDENAALGTVGITAASTDADI-T 3078

Query: 289  NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD-GGDPPRS 347
            +  +TY +     TG  +  I  +     V +   +DRET +   + V AT   G    +
Sbjct: 3079 SGAITYAIVGG--TGATNFVIDAETGVVSVASGANIDRETGSSLTIDVQATPANGAASVT 3136

Query: 348  ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV-VTLTATDAD-EDNRLHYEITG 405
            +T T                      E++E+  PGT V +  +A+DAD   N + Y +T 
Sbjct: 3137 STFTITINDVNEFDVTTPVDSNAAANEVSENAGPGTLVGIVASASDADATTNGVTYSLT- 3195

Query: 406  GNTRGRFSITSQNGRGLITVAQPL---DFKQERRYVLTVSATDSGGRSDTAMVQINITDA 462
             +  G F I +  G   ++ A      DF+    + +TV A  + G + T    I I DA
Sbjct: 3196 DSAGGIFEIDAATGEVRLSTAAMAPRPDFETAESHTITVQAMSADGSTSTEDFTITILDA 3255

Query: 463  NNYAPVFE-NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521
            N+ APVF  NA    SV E+    T+V+ +SATD D    + I++++       A    +
Sbjct: 3256 NDTAPVFAINA--AQSVAENE---TSVVRLSATDVDTD-QSGISFTIVGGDDQAAFRVVE 3309

Query: 522  QQFVINPQ-TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580
             + V   +   A       D    + Y + V A DG   ++++     I+V DVN+    
Sbjct: 3310 DEGVYTLEFVSAPDFEMPTDMGGNNIYNVVVEAFDG--TNMTEQA-FAITVTDVNEAPTA 3366

Query: 581  FKQQLYTANIMEDALVGT--SVSQVGATDADVGLNG 614
                  T+ + E++++G+   V+ +  TD  +G+NG
Sbjct: 3367 VSLDNTTSTLAENSVIGSGIKVADITITDDALGVNG 3402



 Score = 97.1 bits (231), Expect = 6e-18
 Identities = 143/571 (25%), Positives = 228/571 (39%), Gaps = 47/571 (8%)

Query: 265  SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV-YTSGQ 323
            S ++ V +   +          G + +L+  ++     GN      ID  +G +   +GQ
Sbjct: 2944 SAADGVTVAEDLDAATVIATASGTDVDLSDVLSYSISAGNDAGLFEIDATTGDISLVAGQ 3003

Query: 324  -LDRETQAKYQLLVTATDG-GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381
             LD ET  ++ L VT +DG G                          G     + E+   
Sbjct: 3004 SLDAETDIEHVLTVTVSDGNGGTDTQEITVNVTDVDDNLTTAPVDADGVAGGSVDENAAL 3063

Query: 382  GTPVVTLTATDAD-EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440
            GT  +T  +TDAD     + Y I GG     F I ++ G  +++VA   +  +E    LT
Sbjct: 3064 GTVGITAASTDADITSGAITYAIVGGTGATNFVIDAETG--VVSVASGANIDRETGSSLT 3121

Query: 441  --VSATDSGGRSD-TAMVQINITDANNY---APVFENAPYTASVFEDAPIGTTV-LVVSA 493
              V AT + G +  T+   I I D N +    PV  NA     V E+A  GT V +V SA
Sbjct: 3122 IDVQATPANGAASVTSTFTITINDVNEFDVTTPVDSNAAAN-EVSENAGPGTLVGIVASA 3180

Query: 494  TDSDVGINAQITYSLSSEISNEAVAHHDQQF-VINPQTGAITTNKLLDRETMSGYLLTVT 552
            +D+D   N  +TYSL+   S   +   D     +   T A+      D ET   + +TV 
Sbjct: 3181 SDADATTNG-VTYSLTD--SAGGIFEIDAATGEVRLSTAAMAPRP--DFETAESHTITVQ 3235

Query: 553  ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612
            A        + T D  I+++D ND  PVF       ++ E+    TSV ++ ATD D   
Sbjct: 3236 AMSAD--GSTSTEDFTITILDANDTAPVFAINA-AQSVAENE---TSVVRLSATDVDTDQ 3289

Query: 613  NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE---SVATHDLKAVAIDGGTPPQSS 669
            +G     +   D+     V D     +    A D E    +  +++  V ++       +
Sbjct: 3290 SGISFTIVGGDDQAAFRVVEDEGVYTLEFVSAPDFEMPTDMGGNNIYNVVVEAFDGTNMT 3349

Query: 670  TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT--TIGEIRAHDPDEGPNAVVHYSIK 727
                 I + D+N++P     D  T  ++ENS IG+   + +I   D   G N V   ++ 
Sbjct: 3350 EQAFAITVTDVNEAPTAVSLDNTTSTLAENSVIGSGIKVADITITDDALGVNGV---TLT 3406

Query: 728  GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDV 787
            G D +    + T  G         ++L Y      +E    A +   +N V VE+    V
Sbjct: 3407 GADAAFFAVVSTDTG---------LELHYVGEAPNFEAPADAGADNSFN-VTVEVDDGTV 3456

Query: 788  NDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA 818
             D      DF +   +  +  PV    +VPA
Sbjct: 3457 GDTPDATTDFTLTVTDVNEA-PVA--NQVPA 3484



 Score = 76.6 bits (180), Expect = 9e-12
 Identities = 135/565 (23%), Positives = 224/565 (39%), Gaps = 68/565 (12%)

Query: 126  VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
            V+D    T T+ VN+  +  N    ++    +S  ED +++       + ATD D     
Sbjct: 4277 VTDGNGGTDTVVVNVTVNAVNDAPVAQADAAISTGEDQAISGT-----VTATDVD---GD 4328

Query: 186  AIRYAIIGGNTQMQFSID-SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
            ++ +A+  G      S+  S +G  +     D+    ++ + +   +GG+    +T  + 
Sbjct: 4329 SLSFALATGGAPANGSVTISANGGYTYTPDADFNGTDAFTVSVTDGNGGT----DTVVVN 4384

Query: 245  INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
            + +  VND AP         S  E+  I  ++    A D D      L++ +       N
Sbjct: 4385 VTVNAVND-APVAQADA-AISTGEDQAISGTVT---ATDVD---GDSLSFALASGGAPAN 4436

Query: 305  VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364
                +TI    G+ YT    D +        V+ TDG       T T             
Sbjct: 4437 GS--VTISANGGYTYTP---DADFNGTDAFTVSVTDGN----GGTDTVVVNVTVNAVNDA 4487

Query: 365  XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLIT 424
                    +   ED+       T+TATD D D+ L + +  G      S+T  +  G  T
Sbjct: 4488 PVAQADAAISTGEDQAISG---TVTATDVDGDS-LSFALATGGAPANGSVTV-SANGGYT 4542

Query: 425  VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
                 DF     +  TVS TD  G +DT +V + + +A N APV + A    S  ED  I
Sbjct: 4543 YTPDADFNGTDAF--TVSVTDGNGGTDTVVVNVTV-NAVNDAPVAQ-ADAAISTGEDQAI 4598

Query: 485  GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
              T   V+ATD D      ++++L+   +  A A+       N   G  T     D    
Sbjct: 4599 SGT---VTATDVD---GDSLSFALA---TGGAPANGSVTVSAN---GGYTYTPDADFNGT 4646

Query: 545  SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT--SVSQ 602
              + ++VT  +GG    +DT  V ++V  VND  PV      T ++ EDA   +   V+ 
Sbjct: 4647 DAFTVSVTDGNGG----TDTVVVNVTVNAVND-APVVTLANVTTDVDEDADTTSRIKVAD 4701

Query: 603  VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID- 661
            +  +D + G+N      L     +   F I   +  +R   +LD E+ A  D+     D 
Sbjct: 4702 IVVSDDEQGIN-----TLALAGADAALFEIVGTALFLRAGASLDFETKAQLDVSVTVNDA 4756

Query: 662  --GGTPPQSSTVIVHIKIEDINDSP 684
              GGTP    T  + + + D+++ P
Sbjct: 4757 SVGGTP--DGTASLSLTVNDVDEGP 4779



 Score = 72.9 bits (171), Expect = 1e-10
 Identities = 166/704 (23%), Positives = 265/704 (37%), Gaps = 79/704 (11%)

Query: 36   ASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGR 95
            A+  T+  T + T QD G           VT D   P              +D  RI   
Sbjct: 4072 AAGVTSTATFQYTVQDSGSAQSTTTVTVQVTGDNDAPTAVQVTLLASN---EDTVRIITE 4128

Query: 96   SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155
            +  L   + +D   V   T L   +   S V D    T T   ++ D+ D    FS   Y
Sbjct: 4129 AQLLSGASDVDTGAVLEITALALTSGNGSLV-DNEDGTWTYTPDLNDNGD--VTFS---Y 4182

Query: 156  TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQM---QFSIDSLSGDVSLV 212
            TVS D  ++ T +  +  +   DA V    A   AI  G  Q      +   + GD SL 
Sbjct: 4183 TVS-DGLLTATASATLDLLPVNDAPVAQADA---AISTGEDQAISGTVTATDVDGD-SLS 4237

Query: 213  KTLDYEQVRSYRLVIRAQDGG---SPSR--SNTTQLLINIRDVNDNAPRFYTSLFQESVS 267
              L      +   V  + +GG   +P    + T    +++ D N        ++   +V+
Sbjct: 4238 FALASGGAPANGSVTISANGGYTYTPDADFNGTDAFTVSVTDGNGGTDTVVVNVTVNAVN 4297

Query: 268  ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY------TGNVDL--PITIDPRSGWVY 319
            +  P+  +   +   + D+ ++  +T T  D D       TG       +TI    G+ Y
Sbjct: 4298 D-APVAQADAAISTGE-DQAISGTVTATDVDGDSLSFALATGGAPANGSVTISANGGYTY 4355

Query: 320  TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE 379
            T    D +        V+ TDG       T T                     +   ED+
Sbjct: 4356 TP---DADFNGTDAFTVSVTDGN----GGTDTVVVNVTVNAVNDAPVAQADAAISTGEDQ 4408

Query: 380  PPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL 439
                   T+TATD D D+ L + +  G      S+T  +  G  T     DF     +  
Sbjct: 4409 AISG---TVTATDVDGDS-LSFALASGGAPANGSVTI-SANGGYTYTPDADFNGTDAF-- 4461

Query: 440  TVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499
            TVS TD  G +DT +V + +   N+ APV + A    S  ED  I  TV   +ATD D  
Sbjct: 4462 TVSVTDGNGGTDTVVVNVTVNAVND-APVAQ-ADAAISTGEDQAISGTV---TATDVD-- 4514

Query: 500  INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559
                ++++L++     A A+       N   G  T     D      + ++VT  +GG  
Sbjct: 4515 -GDSLSFALAT---GGAPANGSVTVSAN---GGYTYTPDADFNGTDAFTVSVTDGNGG-- 4565

Query: 560  SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619
              +DT  V ++V  VND  PV +     +   + A+ GT    V ATD D      + + 
Sbjct: 4566 --TDTVVVNVTVNAVND-APVAQADAAISTGEDQAISGT----VTATDVD---GDSLSFA 4615

Query: 620  LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679
            L          V   A+G        D        +     +GGT     TV+V++ +  
Sbjct: 4616 LATGGAPANGSVTVSANGGYTYTPDADFNGTDAFTVSVTDGNGGT----DTVVVNVTVNA 4671

Query: 680  INDSPPVFESDCLTFYISENSPIGTTI--GEIRAHDPDEGPNAV 721
            +ND+P V  ++ +T  + E++   + I   +I   D ++G N +
Sbjct: 4672 VNDAPVVTLAN-VTTDVDEDADTTSRIKVADIVVSDDEQGINTL 4714



 Score = 71.7 bits (168), Expect = 3e-10
 Identities = 176/719 (24%), Positives = 265/719 (36%), Gaps = 84/719 (11%)

Query: 160  DEDISVTDNPVI--AKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVK--TL 215
            D D+ + D P I  A    T   V      R   I G   +  ++ S +GD +L    +L
Sbjct: 4016 DTDVDINDIPTIVDASSSVTATAVATADGFRITTIDG---VVVNL-SANGDYTLTAPDSL 4071

Query: 216  DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275
                  +       QD GS    +TT + + +   ND       +L   +      I  +
Sbjct: 4072 AAGVTSTATFQYTVQDSGSAQ--STTTVTVQVTGDNDAPTAVQVTLLASNEDTVRIITEA 4129

Query: 276  IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG-WVYTSGQLDRETQAKYQL 334
             +   A D D G   E+T        +GN  L   +D   G W YT    D         
Sbjct: 4130 QLLSGASDVDTGAVLEITALALT---SGNGSL---VDNEDGTWTYTP---DLNDNGDVTF 4180

Query: 335  LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394
              T +DG       TAT                     +   ED+       T+TATD D
Sbjct: 4181 SYTVSDG-----LLTATASATLDLLPVNDAPVAQADAAISTGEDQAISG---TVTATDVD 4232

Query: 395  EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM 454
             D+ L + +  G      S+T  +  G  T     DF     +  TVS TD  G +DT +
Sbjct: 4233 GDS-LSFALASGGAPANGSVTI-SANGGYTYTPDADFNGTDAF--TVSVTDGNGGTDTVV 4288

Query: 455  VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514
            V + + +A N APV + A    S  ED  I  T   V+ATD D      ++++L+   + 
Sbjct: 4289 VNVTV-NAVNDAPVAQ-ADAAISTGEDQAISGT---VTATDVD---GDSLSFALA---TG 4337

Query: 515  EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574
             A A+       N   G  T     D      + ++VT  +GG    +DT  V ++V  V
Sbjct: 4338 GAPANGSVTISAN---GGYTYTPDADFNGTDAFTVSVTDGNGG----TDTVVVNVTVNAV 4390

Query: 575  NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634
            ND  PV +     +   + A+ GT    V ATD D      + + L          V   
Sbjct: 4391 ND-APVAQADAAISTGEDQAISGT----VTATDVD---GDSLSFALASGGAPANGSVTIS 4442

Query: 635  ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694
            A+G        D        +     +GGT     TV+V++ +  +ND+ PV ++D    
Sbjct: 4443 ANGGYTYTPDADFNGTDAFTVSVTDGNGGT----DTVVVNVTVNAVNDA-PVAQADA-AI 4496

Query: 695  YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDL 754
               E+  I    G + A D D G +     +  G   + S ++    G          D 
Sbjct: 4497 STGEDQAIS---GTVTATDVD-GDSLSFALATGGAPANGSVTVSANGG-----YTYTPDA 4547

Query: 755  DYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG 814
            D+      + + +   +    + V V + V  VND APV +    I             G
Sbjct: 4548 DFNG-TDAFTVSVTDGNGGT-DTVVVNVTVNAVND-APVAQADAAISTGEDQAIS----G 4600

Query: 815  RVPAYDADVTDKLQYRILSGN-NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872
             V A D D  D L + + +G   AN  +     G  T +P  + N     T  VSVTDG
Sbjct: 4601 TVTATDVD-GDSLSFALATGGAPANGSVTVSANGGYTYTPDADFNGTDAFT--VSVTDG 4656



 Score = 49.6 bits (113), Expect = 0.001
 Identities = 90/379 (23%), Positives = 143/379 (37%), Gaps = 43/379 (11%)

Query: 225  LVIRAQDGGSPSR----SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQ 280
            L +   DGGS       ++   + I +  VND AP     +  E   +      +++   
Sbjct: 2260 LTMTTDDGGSTGEGGALTDIDTVTITVNPVND-APVVEGPVSAEQTEDAEGFTVNLLS-G 2317

Query: 281  AYDADEGVNAELTYTMTDKDYTGNVDLP-----ITIDPRSGWVYTSGQLDRETQAKYQLL 335
            A D D G    ++  M D      V +      +T+DP +   YT+  +       Y   
Sbjct: 2318 ASDVDTGDVLTVSGLMLDSGDDSGVTVSMDGNSLTVDPDA---YTALAVGESAVITYSYT 2374

Query: 336  VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395
            VT  +GG+  ++AT T                P    V+ A D+   +   TL  +D D 
Sbjct: 2375 VTDGNGGEVSQTATITITGANDGPVLEDVTTAPAI--VDTAGDDTLSSVSDTLVGSDVDN 2432

Query: 396  DNRLHYEITG-----GNT--RGRFSITSQNGRGLITVA------QPLDFKQERRYVLTVS 442
               L Y I+G     G T   G++   +    G  T        Q L    E     T+ 
Sbjct: 2433 GAVLTYAISGQEPVMGETSLEGKYGTLTVLSDGSYTYTPDAAKLQGLAADAEPNETFTIV 2492

Query: 443  ATDSGGRSDTAMVQINITDANNYAPVFE----NAPYTASVFEDAPIGTTVLVVSATDSDV 498
             TD  G  DTA + ++IT AN+   +      N   TA+  + A  G T   +SATD D 
Sbjct: 2493 VTDEHGAFDTATLTVDITPANDTPELASVDAINITDTAAADDFAAQGGT---LSATDRDS 2549

Query: 499  GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558
            G    + YS++ +   E      Q F  +    A+ T   L+   +     T+T +  G 
Sbjct: 2550 GHVDAMVYSIAGQEVAEGAT--SQTFYFDRVGNAVVTEAPLNGVELG----TLTVQSSGA 2603

Query: 559  PSLSDTTDVEISVVDVNDN 577
             S  +  D  I+ +  + N
Sbjct: 2604 YSF-EPNDAGINSLRADQN 2621



 Score = 39.1 bits (87), Expect = 1.7
 Identities = 35/127 (27%), Positives = 55/127 (43%), Gaps = 9/127 (7%)

Query: 376  AEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435
            AEDE  G    T+ A D D+   L + I  G++    S+T     G  +     +F    
Sbjct: 3621 AEDE--GAITGTIVADDVDDGAILGFSIEDGDSAANGSVTVDPNTGTWSYTPDANFNGVD 3678

Query: 436  RYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN----APYTASVFEDAPIGTTVLV- 490
             + +TVS  D  G S T +V + +T  N+   +  +    A +  +V   AP+ T +   
Sbjct: 3679 SFTVTVS--DGLGGSVTQVVDVTVTAVNDATEIDVSSQVAATHVEAVDAAAPVATLIAAQ 3736

Query: 491  VSATDSD 497
             S TD D
Sbjct: 3737 ASLTDVD 3743



 Score = 37.5 bits (83), Expect = 5.3
 Identities = 97/471 (20%), Positives = 175/471 (37%), Gaps = 42/471 (8%)

Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332
           G   + V   DAD+   A +  T++D   T    L    D  +    ++ QLD  +    
Sbjct: 190 GDQTLTVTGIDADQ---ASVVVTVSDGTTTVTATLGAITDGSATATLSAAQLDTLSDGTL 246

Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392
              VT TD      ++T T                     V+ +         V  +  D
Sbjct: 247 TATVTVTDVSTNVATSTDTIALDTIADAAPNLSVAFEGAGVDDSTFNAGEAIQVAFSGID 306

Query: 393 ADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT 452
           AD    L    TGG +     +TS +   +   +  +D   +    +T+  TD+ G  +T
Sbjct: 307 ADATGTLTITSTGGGSVVVAGLTSVSSSPISLDSMQMDALSDGTLSVTLDVTDTAG--NT 364

Query: 453 AMVQINITDANNYAPVFENAPYT------ASVFEDAPIGTTVLVVSATDS-DVGINAQIT 505
           A VQ N  D +  AP+  +           +V +    G+  L ++  ++ D  ++  +T
Sbjct: 365 AQVQSNGFDLDASAPMIASVTLAGGSGVEGTVIDGDVDGSVTLTIAFNEAMDTAVDPTVT 424

Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT-ARDGGVPSLSDT 564
              +S  S       ++ + ++  +  IT   +     ++   + V+ A+D     +S  
Sbjct: 425 LDTASASS---FTEAERAWSMDGLSLTITYTVVDQNVDLAAITVGVSGAQDVAGNVISAV 481

Query: 565 TDVEISVVDVNDNEPVFKQQLYTANIMED--ALVGTSV---SQVGATDADVGLNG----R 615
           ++V        ++     + +  A I +   A  GT +      GA      L G     
Sbjct: 482 SEVATGTAIDTESTASETESVTIAEIPDQNAATTGTPIVLAKLSGADGTTYALTGEAAVN 541

Query: 616 IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675
            H E+   D E+G  V    +   R    L+ E+  + D+     D      +S  ++ I
Sbjct: 542 AHVEI-VSDGEDGFMVQIIDTEAARGFFDLE-ENGPSFDISVTGTDNAGNTTAS--VLSI 597

Query: 676 KIEDINDSPPVF--ESDCLTFYISEN---------SPIGTTIGEIRAHDPD 715
            + D+ND+P +   E+D LT  ++E          +P GTT G    HD D
Sbjct: 598 TLTDLNDAPELVPGEND-LTGTVTEREDGVLGENATPFGTT-GTFGVHDDD 646


>UniRef50_A7T102 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 341

 Score =  149 bits (361), Expect = 1e-33
 Identities = 110/359 (30%), Positives = 166/359 (46%), Gaps = 32/359 (8%)

Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259
           FS++S++G+++L   LD+E  RSY LV+ A+D G P   + T ++I + D++D  PRF  
Sbjct: 4   FSLNSVNGELTLGGPLDFEVARSYMLVVIAEDLGVPKLESRTTVIIEVTDISDMPPRFLQ 63

Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319
           S + + + EN PI               V   + Y +   D      +   IDP SG +Y
Sbjct: 64  SSYLKEIEENTPIP--------------VFRRVLYHLVGAD-----SVKFAIDPTSGTLY 104

Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPR-SATATXXXXXXXXXXXXXXFMPGQYEVELAED 378
            +  LD E Q  +   V AT+     + SA A+              F    Y   + E+
Sbjct: 105 INKTLDYEKQINFTFDVVATETDTSEKFSANASVTLTLININDNKPMFAKSSYNYTMDEE 164

Query: 379 EPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436
             PGT +  +TATDAD      L YE+ GG     FS+ + NG   I+ AQ LD+    +
Sbjct: 165 ITPGTHIADITATDADLGTFGALTYELRGGQA-AYFSVNADNGT--ISAAQILDYDTLPQ 221

Query: 437 YVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
           Y  ++ A D GG       A V + + D N+  P F   PYT+ + E+ P GT V  V+A
Sbjct: 222 YQFSLMAKDGGGFYQEIAIATVTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTA 281

Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552
           TD D G N ++    S+        H D Q  +N       T ++ D  T++  +  VT
Sbjct: 282 TDKDSGENGRV----SAYDHGVPSRHRDVQLTVNVLDENDNTPQITDGLTITTNISEVT 336



 Score =  127 bits (307), Expect = 4e-27
 Identities = 92/316 (29%), Positives = 151/316 (47%), Gaps = 32/316 (10%)

Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPV 468
           FS+ S NG   +T+  PLDF+  R Y+L V A D G     S T ++ I +TD ++  P 
Sbjct: 4   FSLNSVNGE--LTLGGPLDFEVARSYMLVVIAEDLGVPKLESRTTVI-IEVTDISDMPPR 60

Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528
           F  + Y   + E+ PI               +  ++ Y L        V     +F I+P
Sbjct: 61  FLQSSYLKEIEENTPIP--------------VFRRVLYHL--------VGADSVKFAIDP 98

Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYT 587
            +G +  NK LD E    +   V A +       S    V ++++++NDN+P+F +  Y 
Sbjct: 99  TSGTLYINKTLDYEKQINFTFDVVATETDTSEKFSANASVTLTLININDNKPMFAKSSYN 158

Query: 588 ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647
             + E+   GT ++ + ATDAD+G  G + YEL  +  +   F ++  +G I   + LD 
Sbjct: 159 YTMDEEITPGTHIADITATDADLGTFGALTYEL--RGGQAAYFSVNADNGTISAAQILDY 216

Query: 648 ESVATHDLKAVAIDGGTPPQSSTV-IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706
           +++  +    +A DGG   Q   +  V + ++D+ND+ P F     T  I+EN P GT +
Sbjct: 217 DTLPQYQFSLMAKDGGGFYQEIAIATVTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIV 276

Query: 707 GEIRAHDPDEGPNAVV 722
            ++ A D D G N  V
Sbjct: 277 FQVTATDKDSGENGRV 292



 Score =  125 bits (302), Expect = 2e-26
 Identities = 70/205 (34%), Positives = 115/205 (56%), Gaps = 6/205 (2%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F ID  SG L    +LD EK   +T  V AT+  +  S++ S+ A++ + +I+ NDN P 
Sbjct: 94  FAIDPTSGTLYINKTLDYEKQINFTFDVVATE--TDTSEKFSANASVTLTLININDNKPM 151

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209
           F++ +Y  ++DE+I  T    IA I ATDAD+G   A+ Y + GG     FS+++ +G +
Sbjct: 152 FAKSSYNYTMDEEI--TPGTHIADITATDADLGTFGALTYELRGGQAAY-FSVNADNGTI 208

Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT-TQLLINIRDVNDNAPRFYTSLFQESVSE 268
           S  + LDY+ +  Y+  + A+DGG   +      + + ++DVNDN P F    +   ++E
Sbjct: 209 SAAQILDYDTLPQYQFSLMAKDGGGFYQEIAIATVTVTLQDVNDNDPEFTGMPYTSDIAE 268

Query: 269 NVPIGYSIVRVQAYDADEGVNAELT 293
           N+P G  + +V A D D G N  ++
Sbjct: 269 NLPAGTIVFQVTATDKDSGENGRVS 293



 Score =  114 bits (275), Expect = 3e-23
 Identities = 88/307 (28%), Positives = 148/307 (48%), Gaps = 29/307 (9%)

Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374
           +G +   G LD E    Y L+V A D G P   +  T              F+   Y  E
Sbjct: 10  NGELTLGGPLDFEVARSYMLVVIAEDLGVPKLESRTTVIIEVTDISDMPPRFLQSSYLKE 69

Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434
           + E+ P   PV            R+ Y + G ++  +F+I   +G   + + + LD++++
Sbjct: 70  IEENTP--IPVF----------RRVLYHLVGADSV-KFAIDPTSGT--LYINKTLDYEKQ 114

Query: 435 RRYVLTVSATDSGGR---SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491
             +   V AT++      S  A V + + + N+  P+F  + Y  ++ E+   GT +  +
Sbjct: 115 INFTFDVVATETDTSEKFSANASVTLTLININDNKPMFAKSSYNYTMDEEITPGTHIADI 174

Query: 492 SATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTV 551
           +ATD+D+G    +TY    E+     A+    F +N   G I+  ++LD +T+  Y  ++
Sbjct: 175 TATDADLGTFGALTY----ELRGGQAAY----FSVNADNGTISAAQILDYDTLPQYQFSL 226

Query: 552 TARDGG--VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609
            A+DGG     ++  T V +++ DVNDN+P F    YT++I E+   GT V QV ATD D
Sbjct: 227 MAKDGGGFYQEIAIAT-VTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKD 285

Query: 610 VGLNGRI 616
            G NGR+
Sbjct: 286 SGENGRV 292



 Score =  101 bits (243), Expect = 2e-19
 Identities = 82/307 (26%), Positives = 139/307 (45%), Gaps = 27/307 (8%)

Query: 90  FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149
           F ++  +G L     LD E    Y ++V A D   P   +L S  T+ + + D +D  P+
Sbjct: 4   FSLNSVNGELTLGGPLDFEVARSYMLVVIAEDLGVP---KLESRTTVIIEVTDISDMPPR 60

Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209
           F + +Y   ++E+  +   PV  ++              Y ++G ++ ++F+ID  SG +
Sbjct: 61  FLQSSYLKEIEENTPI---PVFRRVL-------------YHLVGADS-VKFAIDPTSGTL 103

Query: 210 SLVKTLDYEQVRSYRL-VIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268
            + KTLDYE+  ++   V+  +   S   S    + + + ++NDN P F  S +  ++ E
Sbjct: 104 YINKTLDYEKQINFTFDVVATETDTSEKFSANASVTLTLININDNKPMFAKSSYNYTMDE 163

Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328
            +  G  I  + A DAD G    LTY     +  G      +++  +G +  +  LD +T
Sbjct: 164 EITPGTHIADITATDADLGTFGALTY-----ELRGGQAAYFSVNADNGTISAAQILDYDT 218

Query: 329 QAKYQLLVTATDGGD-PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387
             +YQ  + A DGG      A AT              F    Y  ++AE+ P GT V  
Sbjct: 219 LPQYQFSLMAKDGGGFYQEIAIATVTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQ 278

Query: 388 LTATDAD 394
           +TATD D
Sbjct: 279 VTATDKD 285



 Score =  100 bits (240), Expect = 5e-19
 Identities = 97/355 (27%), Positives = 146/355 (41%), Gaps = 37/355 (10%)

Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583
           F +N   G +T    LD E    Y+L V A D GVP L   T V I V D++D  P F Q
Sbjct: 4   FSLNSVNGELTLGGPLDFEVARSYMLVVIAEDLGVPKLESRTTVIIEVTDISDMPPRFLQ 63

Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK 643
             Y   I E+                + +  R+ Y L   D  +  F IDP SG +  NK
Sbjct: 64  SSYLKEIEENT--------------PIPVFRRVLYHLVGADSVK--FAIDPTSGTLYINK 107

Query: 644 ALDRESVATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702
            LD E         VA +  T  + S+   V + + +IND+ P+F      + + E    
Sbjct: 108 TLDYEKQINFTFDVVATETDTSEKFSANASVTLTLININDNKPMFAKSSYNYTMDEEITP 167

Query: 703 GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES-PRK 761
           GT I +I A D D G    + Y ++GG  +  FS+    G+  A  +    LDY++ P+ 
Sbjct: 168 GTHIADITATDADLGTFGALTYELRGG-QAAYFSVNADNGTISAAQI----LDYDTLPQY 222

Query: 762 KYELVIRAASPPLWNDV---RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA 818
           ++ L+ +      + ++    V + + DVNDN P         ++  +  P G       
Sbjct: 223 QFSLMAKDGG-GFYQEIAIATVTVTLQDVNDNDPEFTGMPYT-SDIAENLPAGTI----V 276

Query: 819 YDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGV 873
           +    TDK      SG N  +   +    S     QL  NV         +TDG+
Sbjct: 277 FQVTATDK-----DSGENGRVSAYDHGVPSRHRDVQLTVNVLDENDNTPQITDGL 326



 Score = 39.9 bits (89), Expect = 0.99
 Identities = 17/48 (35%), Positives = 26/48 (54%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEV 58
           + + D ND+ P F    Y + + E   +GT V  + ATD+D G+N  V
Sbjct: 245 VTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRV 292


>UniRef50_Q6R8F2 Cluster: Epithelial cadherin precursor (E-cadherin)
           (Cadherin-1) (CD324 antigen) [Contains: E-Cad/CTF1;
           E-Cad/CTF2; E-Cad/CTF3]; n=7; Laurasiatheria|Rep:
           Epithelial cadherin precursor (E-cadherin) (Cadherin-1)
           (CD324 antigen) [Contains: E-Cad/CTF1; E-Cad/CTF2;
           E-Cad/CTF3] - Bos taurus (Bovine)
          Length = 882

 Score =  149 bits (361), Expect = 1e-33
 Identities = 120/401 (29%), Positives = 185/401 (46%), Gaps = 31/401 (7%)

Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259
           F I+  +G + + + LD EQ+  Y L   A      +     +++I + D NDN P+F  
Sbjct: 205 FIIERETGWLKVTQPLDREQIAKYILFSHAVSSNGQAIEEPMEIVITVTDQNDNKPQFTQ 264

Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVN---AELTYTMTDKDYTGNVDLPITIDPRSG 316
            +F+ S  E    G S+++V A D D+ VN   A + YT+  +D     +   TI+  +G
Sbjct: 265 EVFKASALEGALPGTSVMQVTATDIDDEVNTYTAAIGYTIPAQDPMLPHNKMFTINKETG 324

Query: 317 --WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374
              V T+G LDRE+   Y L+V A D      S TAT              F P  Y   
Sbjct: 325 VISVLTTG-LDRESFPTYTLMVQAADLNGEGLSTTATAVITVLDTNDNAPRFNPTTYVGS 383

Query: 375 LAEDEPPGTPVVTLTATDADEDN----RLHYEITGGNTRGRFSITSQ-NGRGLITVAQPL 429
           + E+E     + TLT TDAD+ N       Y +   N +    +T      G +  A+ L
Sbjct: 384 VPENE-ANVAITTLTVTDADDPNTPAWEAVYTVLNDNEKQFIVVTDPVTNEGTLKTAKGL 442

Query: 430 DFKQERRYVLTVSATDSGG-----RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
           DF+ +++Y+L V+ T+         + TA V +++ D N  AP+F        V ED  +
Sbjct: 443 DFEAKQQYILYVAVTNVAPFEVTLPTSTATVTVDVIDVNE-APIFVPPQKRVEVPEDFGV 501

Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544
           G  +   +A + D  +  +ITY +  + +N           INP+TGAI+T   LDRE +
Sbjct: 502 GLEITSYTAREPDTFMEQKITYRIWRDTAN--------WLEINPETGAISTRAELDREDV 553

Query: 545 -----SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580
                S Y   + A D G P  + T  + + + DVNDN PV
Sbjct: 554 DHVKNSTYTALIIATDNGSPPATGTGTLLLFLDDVNDNGPV 594



 Score =  140 bits (339), Expect = 5e-31
 Identities = 148/520 (28%), Positives = 235/520 (45%), Gaps = 51/520 (9%)

Query: 391 TDADEDNRLHYEITGGNTR----GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446
           ++ +++ ++ Y ITG        G F I  + G   + V QPLD +Q  +Y+L   A  S
Sbjct: 180 SNKEKETQVFYSITGQRADTPPVGVFIIERETG--WLKVTQPLDREQIAKYILFSHAVSS 237

Query: 447 GGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN--- 501
            G++  +   + I +TD N+  P F    + AS  E A  GT+V+ V+ATD D  +N   
Sbjct: 238 NGQAIEEPMEIVITVTDQNDNKPQFTQEVFKASALEGALPGTSVMQVTATDIDDEVNTYT 297

Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL-LDRETMSGYLLTVTARDGGVPS 560
           A I Y++ ++   + +  H++ F IN +TG I+     LDRE+   Y L V A D     
Sbjct: 298 AAIGYTIPAQ---DPMLPHNKMFTINKETGVISVLTTGLDRESFPTYTLMVQAADLNGEG 354

Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620
           LS T    I+V+D NDN P F    Y  ++ E+     +++ +  TDAD           
Sbjct: 355 LSTTATAVITVLDTNDNAPRFNPTTYVGSVPENE-ANVAITTLTVTDADDPNTPAWEAVY 413

Query: 621 DPKDREEGSFVI--DPAS--GVIRTNKALDRESVATHDLKAVAIDGGTPPQ----SSTVI 672
              +  E  F++  DP +  G ++T K LD E+   + L  VA+    P +    +ST  
Sbjct: 414 TVLNDNEKQFIVVTDPVTNEGTLKTAKGLDFEAKQQYILY-VAVTNVAPFEVTLPTSTAT 472

Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732
           V + + D+N++P +F        + E+  +G  I    A +PD      + Y I   D +
Sbjct: 473 VTVDVIDVNEAP-IFVPPQKRVEVPEDFGVGLEITSYTAREPDTFMEQKITYRI-WRDTA 530

Query: 733 NSFSLETRQG--SDKAELVTMVDLDYESPRKKYELVIRA--ASPPLWNDVRVEILVTDVN 788
           N   +    G  S +AEL    D+D+        L+I     SPP      + + + DVN
Sbjct: 531 NWLEINPETGAISTRAEL-DREDVDHVKNSTYTALIIATDNGSPPATGTGTLLLFLDDVN 589

Query: 789 DNAPVMK----DF-------QIIFNNYKDCFP-VGPFGRVPAYDADVTDKLQYRILSGNN 836
           DN PV +    DF        II  N  D  P   PF     + A V   ++Y       
Sbjct: 590 DNGPVPEPRTMDFCQRNPEPHIININDPDLPPNTSPFTAELTHGASVNWTIEYN--DQER 647

Query: 837 ANLILLNETT---GSMTLSPQL--NTNVPKLATMEVSVTD 871
            +LIL  + T   G   ++ +L  N N  ++ T++V V D
Sbjct: 648 ESLILKPKKTLELGDHKINLKLIDNQNKDQVTTLDVHVCD 687



 Score =  120 bits (288), Expect = 8e-25
 Identities = 111/360 (30%), Positives = 174/360 (48%), Gaps = 48/360 (13%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKN---AEVEYTIELVTA 67
           I V D ND+ P F  + ++AS  EGA  GT+V+ + ATD D   N   A + YTI     
Sbjct: 250 ITVTDQNDNKPQFTQEVFKASALEGALPGTSVMQVTATDIDDEVNTYTAAIGYTIP--AQ 307

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLVKATDQASPV 126
           D + P +              +F I+  +G + +    LDRE    YT++V+A D     
Sbjct: 308 DPMLPHNK-------------MFTINKETGVISVLTTGLDRESFPTYTLMVQAADLNG-- 352

Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186
            + LS+TAT  + ++D NDN P+F+  TY  SV E+ +   N  I  +  TDAD     A
Sbjct: 353 -EGLSTTATAVITVLDTNDNAPRFNPTTYVGSVPENEA---NVAITTLTVTDADDPNTPA 408

Query: 187 IR--YAIIGGNTQMQFSI--DSLS--GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR--- 237
               Y ++  N + QF +  D ++  G +   K LD+E  + Y L + A    +P     
Sbjct: 409 WEAVYTVLNDN-EKQFIVVTDPVTNEGTLKTAKGLDFEAKQQYILYV-AVTNVAPFEVTL 466

Query: 238 -SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296
            ++T  + +++ DVN+ AP F     +  V E+  +G  I    A + D  +  ++TY +
Sbjct: 467 PTSTATVTVDVIDVNE-APIFVPPQKRVEVPEDFGVGLEITSYTAREPDTFMEQKITYRI 525

Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRE-----TQAKYQLLVTATDGGDPPRSATAT 351
             +D T N    + I+P +G + T  +LDRE       + Y  L+ ATD G PP + T T
Sbjct: 526 W-RD-TANW---LEINPETGAISTRAELDREDVDHVKNSTYTALIIATDNGSPPATGTGT 580



 Score =  119 bits (286), Expect = 1e-24
 Identities = 126/474 (26%), Positives = 200/474 (42%), Gaps = 38/474 (8%)

Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMT-DKDYTGNVDLPITIDPRSGWVYTSGQLD 325
           +E  P   S+V++++    E    ++ Y++T  +  T  V + I I+  +GW+  +  LD
Sbjct: 166 NEKGPFPKSLVQIKSNKEKE---TQVFYSITGQRADTPPVGVFI-IERETGWLKVTQPLD 221

Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385
           RE  AKY L   A                           F    ++    E   PGT V
Sbjct: 222 REQIAKYILFSHAVSSNGQAIEEPMEIVITVTDQNDNKPQFTQEVFKASALEGALPGTSV 281

Query: 386 VTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR-------GLITVAQP-LDFKQERRY 437
           + +TATD D++   +    G     +  +   N         G+I+V    LD +    Y
Sbjct: 282 MQVTATDIDDEVNTYTAAIGYTIPAQDPMLPHNKMFTINKETGVISVLTTGLDRESFPTY 341

Query: 438 VLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFE-DAPIGTTVLVVSAT 494
            L V A D  G   S TA   I + D N+ AP F    Y  SV E +A +  T L V+  
Sbjct: 342 TLMVQAADLNGEGLSTTATAVITVLDTNDNAPRFNPTTYVGSVPENEANVAITTLTVTDA 401

Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554
           D       +  Y++ ++   + +   D   V N   G + T K LD E    Y+L V   
Sbjct: 402 DDPNTPAWEAVYTVLNDNEKQFIVVTDP--VTNE--GTLKTAKGLDFEAKQQYILYVAVT 457

Query: 555 DGG---VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG 611
           +     V   + T  V + V+DVN+  P+F        + ED  VG  ++   A + D  
Sbjct: 458 NVAPFEVTLPTSTATVTVDVIDVNE-APIFVPPQKRVEVPEDFGVGLEITSYTAREPDTF 516

Query: 612 LNGRIHYELDPKDREEGSFV-IDPASGVIRTNKALDRESV-----ATHDLKAVAIDGGTP 665
           +  +I Y +    R+  +++ I+P +G I T   LDRE V     +T+    +A D G+P
Sbjct: 517 MEQKITYRIW---RDTANWLEINPETGAISTRAELDREDVDHVKNSTYTALIIATDNGSP 573

Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719
           P + T  + + ++D+ND+ PV E   + F      P       I  +DPD  PN
Sbjct: 574 PATGTGTLLLFLDDVNDNGPVPEPRTMDFCQRNPEP-----HIININDPDLPPN 622



 Score =  111 bits (266), Expect = 4e-22
 Identities = 125/463 (26%), Positives = 203/463 (43%), Gaps = 48/463 (10%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           VF I+  +G L     LDRE++A+Y +   A    S     +     I + + D NDN P
Sbjct: 204 VFIIERETGWLKVTQPLDREQIAKYILFSHAV---SSNGQAIEEPMEIVITVTDQNDNKP 260

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN---SAIRYAIIGGNTQM----QFS 201
           QF+++ +  S  E         + ++ ATD D   N   +AI Y I   +  +     F+
Sbjct: 261 QFTQEVFKASALE--GALPGTSVMQVTATDIDDEVNTYTAAIGYTIPAQDPMLPHNKMFT 318

Query: 202 IDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260
           I+  +G +S++ T LD E   +Y L+++A D      S T   +I + D NDNAPRF  +
Sbjct: 319 INKETGVISVLTTGLDRESFPTYTLMVQAADLNGEGLSTTATAVITVLDTNDNAPRFNPT 378

Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNA--ELTYTM---TDKDYTGNVDLPITIDPRS 315
            +  SV EN     +I  +   DAD+      E  YT+    +K +    D P+T     
Sbjct: 379 TYVGSVPEN-EANVAITTLTVTDADDPNTPAWEAVYTVLNDNEKQFIVVTD-PVT---NE 433

Query: 316 GWVYTSGQLDRETQAKYQLLVTATDGGD-----PPRSATATXXXXXXXXXXXXXXFMPGQ 370
           G + T+  LD E + +Y L V  T+        P  +AT T              F+P Q
Sbjct: 434 GTLKTAKGLDFEAKQQYILYVAVTNVAPFEVTLPTSTATVT---VDVIDVNEAPIFVPPQ 490

Query: 371 YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVA-- 426
             VE+ ED   G  + + TA + D   + ++ Y I   +T     I  + G  + T A  
Sbjct: 491 KRVEVPEDFGVGLEITSYTAREPDTFMEQKITYRI-WRDTANWLEINPETG-AISTRAEL 548

Query: 427 --QPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
             + +D  +   Y   + ATD+G    + T  + + + D N+  PV E  P T    +  
Sbjct: 549 DREDVDHVKNSTYTALIIATDNGSPPATGTGTLLLFLDDVNDNGPVPE--PRTMDFCQRN 606

Query: 483 PIGTTVLVVSATDSDVGIN-AQITYSLSSEIS-NEAVAHHDQQ 523
           P      +++  D D+  N +  T  L+   S N  + ++DQ+
Sbjct: 607 P---EPHIININDPDLPPNTSPFTAELTHGASVNWTIEYNDQE 646


>UniRef50_UPI0000E473B6 Cluster: PREDICTED: similar to cadherin; n=1;
            Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
            cadherin - Strongylocentrotus purpuratus
          Length = 211

 Score =  149 bits (360), Expect = 1e-33
 Identities = 72/172 (41%), Positives = 110/172 (63%), Gaps = 12/172 (6%)

Query: 886  LITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGN 945
            ++T +ML +S+TV++ DM + +FL+P L  FID LA IIP  ++ +Y+FS++D+  +   
Sbjct: 12   MVTHDMLFSSVTVQVEDMQSHEFLTPKLLQFIDALAGIIPANQDLVYLFSIKDEETM--- 68

Query: 946  ILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHE 1005
            ILN++F+A+RPD            +S  +L+ERVYL R+ L+      VLPF DN+C++E
Sbjct: 69   ILNITFAAQRPDGSF---------FSSQYLQERVYLKRSQLSEALGATVLPFGDNLCLNE 119

Query: 1006 PCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCET 1057
             C +F +C+  L F    GF+ + SV+FR I+P T + C CP GFTG  C T
Sbjct: 120  ICSDFYQCIAPLVFWTPGGFIATTSVIFRSIHPETIYKCDCPPGFTGNYCMT 171


>UniRef50_Q4SF84 Cluster: Chromosome undetermined SCAF14607, whole
           genome shotgun sequence; n=2; Tetraodontidae|Rep:
           Chromosome undetermined SCAF14607, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 684

 Score =  149 bits (360), Expect = 1e-33
 Identities = 151/520 (29%), Positives = 231/520 (44%), Gaps = 69/520 (13%)

Query: 177 TDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS 236
           TD DVG  S I+Y + G      F+I+ L+GD+  +K LD E+   Y L  +  +  +  
Sbjct: 164 TDLDVGGKS-IKYILTGEGAGTIFAINELTGDIHAMKRLDREEKAEYTLTAQVINADTDE 222

Query: 237 RSNT-TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY---------SIVRVQAYDADE 286
                ++ +I ++D+NDN P+F  + +  SV E   +G           + RV A DAD+
Sbjct: 223 PLEPPSEFIIKVQDINDNPPQFIEAPYHSSVPEMSAVGCVRALHASGTPVTRVTATDADD 282

Query: 287 ---GVNAELTYTMTD-KDYTGNVDLPITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATDG 341
              G +A+L Y++ + + Y        +IDP S  +  + Q +DRE + +Y +++ A D 
Sbjct: 283 PVYGNSAKLVYSILEGQPY-------FSIDPNSATIKVALQGMDREMREEYLVVIQAKDM 335

Query: 342 GDPPR--SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDN 397
           G      S T T              F    YE  + ED P G     + A D D  E++
Sbjct: 336 GGHMGGLSGTTTVTITLTDINDNPPKFSKNLYEFVIPEDLPTGKMGGKVKANDRDTGENS 395

Query: 398 RLHYEITGGNTRGRFSIT--SQNGRGLITVAQPLDFKQERRYVLTVSATD------SGGR 449
           +  Y I  G+ +G F I   SQ   G++ + +PLD++ +R Y L V AT+      SGG 
Sbjct: 396 KSTYGIVEGDDQGVFEIVTDSQTQEGILRLKKPLDYESKRAYTLKVEATNIRSEPGSGGP 455

Query: 450 -SDTAMVQINITDANNYAPVF----------ENAPYTA---SVFEDAPIGTTVLVVSATD 495
             DTA V+I + D++   PVF          ENAP      SV    P  T   V   T 
Sbjct: 456 FKDTATVKIAVEDSDE-PPVFSKPIYQLEVNENAPINTVIGSVMARDPDSTGSQVSPETS 514

Query: 496 SDVGINAQITYSLSSEISNEA--------------VAHH---DQQFVINPQTGAITTNKL 538
           + + +  Q+ +  + E  +                +  H   ++QF IN   G IT  K 
Sbjct: 515 AILKLLGQVRWFGTQETDSPVGVLNASSQQGFRYFIDRHTDLERQFNINVDDGKITLAKP 574

Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
           LDRET   + +TVTA +    S      V I V+D NDN P F  + Y   + E+   G 
Sbjct: 575 LDRETDMWHNITVTATEVRNHSQISRAIVAIRVMDYNDNAPEFATE-YETFLCENGKPGQ 633

Query: 599 SVSQVGATDADVGLNGR-IHYELDPKDREEGSFVIDPASG 637
            +  + A D D  + G   +Y L P+     +F I    G
Sbjct: 634 VIQTISAVDKDDPIQGHYFNYRLAPEMLNNPNFTIKNNQG 673



 Score =  118 bits (285), Expect = 2e-24
 Identities = 97/324 (29%), Positives = 155/324 (47%), Gaps = 23/324 (7%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           +F I+  +G +     LDRE+ A YT+  +  +  +   + L   +   + + D NDN P
Sbjct: 185 IFAINELTGDIHAMKRLDREEKAEYTLTAQVIN--ADTDEPLEPPSEFIIKVQDINDNPP 242

Query: 149 QFSEKTYTVSVDEDISV-------TDNPVIAKIKATDAD--VGANSA-IRYAIIGGNTQM 198
           QF E  Y  SV E  +V            + ++ ATDAD  V  NSA + Y+I+ G  Q 
Sbjct: 243 QFIEAPYHSSVPEMSAVGCVRALHASGTPVTRVTATDADDPVYGNSAKLVYSILEG--QP 300

Query: 199 QFSIDSLSGDVSL-VKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQLLINIRDVNDNAP 255
            FSID  S  + + ++ +D E    Y +VI+A+D G      S TT + I + D+NDN P
Sbjct: 301 YFSIDPNSATIKVALQGMDREMREEYLVVIQAKDMGGHMGGLSGTTTVTITLTDINDNPP 360

Query: 256 RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315
           +F  +L++  + E++P G    +V+A D D G N++ TY + + D  G  ++      + 
Sbjct: 361 KFSKNLYEFVIPEDLPTGKMGGKVKANDRDTGENSKSTYGIVEGDDQGVFEIVTDSQTQE 420

Query: 316 GWVYTSGQLDRETQAKYQLLVTATD-----GGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370
           G +     LD E++  Y L V AT+     G   P   TAT                P  
Sbjct: 421 GILRLKKPLDYESKRAYTLKVEATNIRSEPGSGGPFKDTATVKIAVEDSDEPPVFSKP-I 479

Query: 371 YEVELAEDEPPGTPVVTLTATDAD 394
           Y++E+ E+ P  T + ++ A D D
Sbjct: 480 YQLEVNENAPINTVIGSVMARDPD 503



 Score =  112 bits (269), Expect = 2e-22
 Identities = 111/354 (31%), Positives = 156/354 (44%), Gaps = 35/354 (9%)

Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553
           TD DVG    I Y L+ E +          F IN  TG I   K LDRE  + Y LT   
Sbjct: 164 TDLDVG-GKSIKYILTGEGAGTI-------FAINELTGDIHAMKRLDREEKAEYTLTAQV 215

Query: 554 RDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG---------TSVSQV 603
            +      L   ++  I V D+NDN P F +  Y +++ E + VG         T V++V
Sbjct: 216 INADTDEPLEPPSEFIIKVQDINDNPPQFIEAPYHSSVPEMSAVGCVRALHASGTPVTRV 275

Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN-KALDRESVATH--DLKAVAI 660
            ATDAD  + G     +      +  F IDP S  I+   + +DRE    +   ++A  +
Sbjct: 276 TATDADDPVYGNSAKLVYSILEGQPYFSIDPNSATIKVALQGMDREMREEYLVVIQAKDM 335

Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720
            G     S T  V I + DIND+PP F  +   F I E+ P G   G+++A+D D G N+
Sbjct: 336 GGHMGGLSGTTTVTITLTDINDNPPKFSKNLYEFVIPEDLPTGKMGGKVKANDRDTGENS 395

Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA--------ASP 772
              Y I  GDD   F + T   + +  L     LDYES ++ Y L + A        +  
Sbjct: 396 KSTYGIVEGDDQGVFEIVTDSQTQEGILRLKKPLDYES-KRAYTLKVEATNIRSEPGSGG 454

Query: 773 PLWNDVRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPAYDADVT 824
           P  +   V+I V D +D  PV     +Q+  N       V   G V A D D T
Sbjct: 455 PFKDTATVKIAVED-SDEPPVFSKPIYQLEVNENAPINTV--IGSVMARDPDST 505



 Score =  100 bits (239), Expect = 7e-19
 Identities = 145/552 (26%), Positives = 224/552 (40%), Gaps = 83/552 (15%)

Query: 230 QDGGSPSRSNTTQLLINIRDVNDNAPRFYT--SLFQESVSENVPIGYSIVRVQAY-DADE 286
           Q  G   R  TT  L   +  + +  + Y+  ++F+E  ++    G+     Q + D D 
Sbjct: 112 QSAGLQHRPATTPTLQTTQTFSSSIKQLYSLITVFEELSNQG---GHYFGYCQLHTDLDV 168

Query: 287 GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPP 345
           G    + Y +T +   G +     I+  +G ++   +LDRE +A+Y L     +   D P
Sbjct: 169 G-GKSIKYILTGEG-AGTI---FAINELTGDIHAMKRLDREEKAEYTLTAQVINADTDEP 223

Query: 346 RSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP---------PGTPVVTLTATDADE- 395
               +               F+   Y   + E             GTPV  +TATDAD+ 
Sbjct: 224 LEPPSEFIIKVQDINDNPPQFIEAPYHSSVPEMSAVGCVRALHASGTPVTRVTATDADDP 283

Query: 396 ----DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR-- 449
                 +L Y I  G     FSI   N   +    Q +D +    Y++ + A D GG   
Sbjct: 284 VYGNSAKLVYSILEGQPY--FSI-DPNSATIKVALQGMDREMREEYLVVIQAKDMGGHMG 340

Query: 450 --SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507
             S T  V I +TD N+  P F    Y   + ED P G     V A D D G N++ TY 
Sbjct: 341 GLSGTTTVTITLTDINDNPPKFSKNLYEFVIPEDLPTGKMGGKVKANDRDTGENSKSTYG 400

Query: 508 LSSEISNEAVAHHDQQFVINPQT--GAITTNKLLDRETMSGYLLTVTARD-----GGVPS 560
           +  E  ++ V     + V + QT  G +   K LD E+   Y L V A +     G    
Sbjct: 401 IV-EGDDQGVF----EIVTDSQTQEGILRLKKPLDYESKRAYTLKVEATNIRSEPGSGGP 455

Query: 561 LSDTTDVEISVVDVND----NEPVFKQQLYTANIMEDALVGTSV--------SQVGA--- 605
             DT  V+I+V D ++    ++P+++ ++   N   + ++G+ +        SQV     
Sbjct: 456 FKDTATVKIAVEDSDEPPVFSKPIYQLEV-NENAPINTVIGSVMARDPDSTGSQVSPETS 514

Query: 606 ----------------TDADVG-LNGR----IHYELDPKDREEGSFVIDPASGVIRTNKA 644
                           TD+ VG LN        Y +D     E  F I+   G I   K 
Sbjct: 515 AILKLLGQVRWFGTQETDSPVGVLNASSQQGFRYFIDRHTDLERQFNINVDDGKITLAKP 574

Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704
           LDRE+   H++   A +     Q S  IV I++ D ND+ P F ++  TF + EN   G 
Sbjct: 575 LDRETDMWHNITVTATEVRNHSQISRAIVAIRVMDYNDNAPEFATEYETF-LCENGKPGQ 633

Query: 705 TIGEIRAHDPDE 716
            I  I A D D+
Sbjct: 634 VIQTISAVDKDD 645


>UniRef50_Q7SZW3 Cluster: Novel protein similar to zebrafish
           epithelial cadherin 1; n=5; Danio rerio|Rep: Novel
           protein similar to zebrafish epithelial cadherin 1 -
           Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 677

 Score =  148 bits (359), Expect = 2e-33
 Identities = 128/466 (27%), Positives = 207/466 (44%), Gaps = 38/466 (8%)

Query: 163 ISVTDN---PVIAKIKATDADVGANSAIRYAIIGGNTQMQ----FSIDSLSGDVSLVKTL 215
           +SV +N   P   ++    +D  +   + Y I G          F ID LSG +++ + L
Sbjct: 102 VSVFENSKGPFPMRLVQIKSDSASEYQMAYKITGEGADQDPKGIFKIDRLSGWINVTQQL 161

Query: 216 DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275
           D E+  SY+LV  A            + ++ + D NDN P F  + F  +V E +  G  
Sbjct: 162 DREEKASYKLVAHATGVDVNIVEKPFEFIVTVTDQNDNKPVFTQNPFNANVPEALEKGEV 221

Query: 276 IVRVQAYDADEGVN---AELTYTMTDKDYTGNVDLPITIDPRSGWVYT-SGQLDRETQAK 331
            + V A DAD+  N   A+++Y +  +D      +   I+P SG +      LDRE  ++
Sbjct: 222 FMTVTATDADDKENTDNADISYAIISQDPPSAKPIMFAINPVSGGISVLETGLDREQWSR 281

Query: 332 YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTAT 391
           Y L++TATD      S T T              F    + V + E++  G  V  L  T
Sbjct: 282 YTLVITATDMNGEGGSTTGTAVITVMDSNDNAPLFEQTSHTVSVPENQV-GAQVANLPVT 340

Query: 392 DADEDNRL----HYEITGGNTRGRFSITSQNGR--GLITVAQPLDFKQERRYVLTVSATD 445
           D DE         Y + GG+  G F++++   R  G+IT  +PLD+++ ++Y+L V   +
Sbjct: 341 DGDEPESTAWSTKYRVIGGDKGGFFNVSTGPSRLEGVITTVKPLDYEKTKQYILFVIVVN 400

Query: 446 SGG-----RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
                    + TA V +N+ D N   P F       S  ED P+G+ +++ +ATD D   
Sbjct: 401 DDKFVGSLPTSTATVTVNVEDVNE-PPEFIPKEKFISKPEDLPVGSNLVIYTATDVDTEK 459

Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS----GYLLTVTARDG 556
             +ITY +  + S          ++    +G I     +DRE+ +     Y   + A D 
Sbjct: 460 KQKITYRIDYDPSG---------WLSITDSGQIQVKTAMDRESSNVKDGKYKALILALDD 510

Query: 557 GVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
            V S  + T  + I + DVNDN PV  ++       E ALV  S++
Sbjct: 511 DVESPATGTGTLVIELQDVNDNAPVINERTIKLCNRESALVLLSIT 556



 Score =  127 bits (306), Expect = 5e-27
 Identities = 127/430 (29%), Positives = 199/430 (46%), Gaps = 36/430 (8%)

Query: 391 TDADEDNRLHYEITGGNT----RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT-- 444
           +D+  + ++ Y+ITG       +G F I   +G   I V Q LD +++  Y L   AT  
Sbjct: 121 SDSASEYQMAYKITGEGADQDPKGIFKIDRLSG--WINVTQQLDREEKASYKLVAHATGV 178

Query: 445 DSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN--- 501
           D           + +TD N+  PVF   P+ A+V E    G   + V+ATD+D   N   
Sbjct: 179 DVNIVEKPFEFIVTVTDQNDNKPVFTQNPFNANVPEALEKGEVFMTVTATDADDKENTDN 238

Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL-LDRETMSGYLLTVTARDGGVPS 560
           A I+Y++   IS +  +     F INP +G I+  +  LDRE  S Y L +TA D     
Sbjct: 239 ADISYAI---ISQDPPSAKPIMFAINPVSGGISVLETGLDREQWSRYTLVITATDMNGEG 295

Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620
            S T    I+V+D NDN P+F+Q  +T ++ E+  VG  V+ +  TD D   +     + 
Sbjct: 296 GSTTGTAVITVMDSNDNAPLFEQTSHTVSVPENQ-VGAQVANLPVTDGDEPESTAWSTKY 354

Query: 621 DPKDREEGSFV---IDPA--SGVIRTNKALDRESVATHDLKAVAIDG----GTPPQSSTV 671
                ++G F      P+   GVI T K LD E    + L  + ++     G+ P +ST 
Sbjct: 355 RVIGGDKGGFFNVSTGPSRLEGVITTVKPLDYEKTKQYILFVIVVNDDKFVGSLP-TSTA 413

Query: 672 IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD 731
            V + +ED+N+ PP F          E+ P+G+ +    A D D      + Y I   D 
Sbjct: 414 TVTVNVEDVNE-PPEFIPKEKFISKPEDLPVGSNLVIYTATDVDTEKKQKITYRIDY-DP 471

Query: 732 SNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIRA----ASPPLWNDVRVEILVTD 786
           S   S+     S + ++ T +D +  + +  KY+ +I A       P      + I + D
Sbjct: 472 SGWLSITD---SGQIQVKTAMDRESSNVKDGKYKALILALDDDVESPATGTGTLVIELQD 528

Query: 787 VNDNAPVMKD 796
           VNDNAPV+ +
Sbjct: 529 VNDNAPVINE 538



 Score =  126 bits (304), Expect = 9e-27
 Identities = 132/476 (27%), Positives = 213/476 (44%), Gaps = 54/476 (11%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAE-VEYTIELVTADT 69
           + V D ND+ PVF    + A+V E    G   +T+ ATD D  +N +  + +  +++ D 
Sbjct: 191 VTVTDQNDNKPVFTQNPFNANVPEALEKGEVFMTVTATDADDKENTDNADISYAIISQD- 249

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLVKATDQASPVSD 128
             P  A             +F I+  SG + +    LDRE+ +RYT+++ ATD      +
Sbjct: 250 --PPSAKPI----------MFAINPVSGGISVLETGLDREQWSRYTLVITATDMN---GE 294

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA-- 186
             S+T T  + ++D NDN P F + ++TVSV E+        +A +  TD D   ++A  
Sbjct: 295 GGSTTGTAVITVMDSNDNAPLFEQTSHTVSVPEN---QVGAQVANLPVTDGDEPESTAWS 351

Query: 187 IRYAIIGGNTQMQFSIDS----LSGDVSLVKTLDYEQVRSYRL-VIRAQD----GGSPSR 237
            +Y +IGG+    F++ +    L G ++ VK LDYE+ + Y L VI   D    G  P  
Sbjct: 352 TKYRVIGGDKGGFFNVSTGPSRLEGVITTVKPLDYEKTKQYILFVIVVNDDKFVGSLP-- 409

Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297
           ++T  + +N+ DVN+  P F       S  E++P+G ++V   A D D     ++TY + 
Sbjct: 410 TSTATVTVNVEDVNE-PPEFIPKEKFISKPEDLPVGSNLVIYTATDVDTEKKQKITYRI- 467

Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRET----QAKYQLLVTATDGGDPPRSATATXX 353
             DY  +  L IT    SG +     +DRE+      KY+ L+ A D  D    AT T  
Sbjct: 468 --DYDPSGWLSIT---DSGQIQVKTAMDRESSNVKDGKYKALILALD-DDVESPATGTGT 521

Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED---NRLHYEITGGNTRG 410
                        +  +  ++L   E   + +V L+ TD D          E  G  ++ 
Sbjct: 522 LVIELQDVNDNAPVINERTIKLCNRE---SALVLLSITDNDGPPFAGPFSVEPQGDTSKN 578

Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYA 466
                ++ G  L   +Q    + E   VL V  TD  G S    +Q ++ D    A
Sbjct: 579 WSVFFNETGHYLSLKSQSRLDQGEYNVVLRV--TDREGESQENTIQASVCDCKGEA 632



 Score =  120 bits (288), Expect = 8e-25
 Identities = 138/524 (26%), Positives = 225/524 (42%), Gaps = 38/524 (7%)

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
           SV EN   G   +R+    +D     ++ Y +T +    +      ID  SGW+  + QL
Sbjct: 103 SVFENSK-GPFPMRLVQIKSDSASEYQMAYKITGEGADQDPKGIFKIDRLSGWINVTQQL 161

Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
           DRE +A Y+L+  AT                          F    +   + E    G  
Sbjct: 162 DREEKASYKLVAHATGVDVNIVEKPFEFIVTVTDQNDNKPVFTQNPFNANVPEALEKGEV 221

Query: 385 VVTLTATDADE----DNR-LHYEITGGNTRGR----FSITSQNGRGLITVAQPLDFKQER 435
            +T+TATDAD+    DN  + Y I   +        F+I   +G G+  +   LD +Q  
Sbjct: 222 FMTVTATDADDKENTDNADISYAIISQDPPSAKPIMFAINPVSG-GISVLETGLDREQWS 280

Query: 436 RYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
           RY L ++ATD  G   S T    I + D+N+ AP+FE   +T SV E+  +G  V  +  
Sbjct: 281 RYTLVITATDMNGEGGSTTGTAVITVMDSNDNAPLFEQTSHTVSVPENQ-VGAQVANLPV 339

Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553
           TD D   +   +      I  +     +     +   G ITT K LD E    Y+L V  
Sbjct: 340 TDGDEPESTAWSTKYRV-IGGDKGGFFNVSTGPSRLEGVITTVKPLDYEKTKQYILFVIV 398

Query: 554 --RDGGVPSL-SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610
              D  V SL + T  V ++V DVN+      ++ + +   ED  VG+++    ATD D 
Sbjct: 399 VNDDKFVGSLPTSTATVTVNVEDVNEPPEFIPKEKFISK-PEDLPVGSNLVIYTATDVDT 457

Query: 611 GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI-----DGGTP 665
               +I Y +   D +   ++    SG I+   A+DRES    D K  A+     D    
Sbjct: 458 EKKQKITYRI---DYDPSGWLSITDSGQIQVKTAMDRESSNVKDGKYKALILALDDDVES 514

Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725
           P + T  + I+++D+ND+ PV     +     E++ +  +I +      ++GP     +S
Sbjct: 515 PATGTGTLVIELQDVNDNAPVINERTIKLCNRESALVLLSITD------NDGPPFAGPFS 568

Query: 726 IK-GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768
           ++  GD S ++S+   +      L +   LD    + +Y +V+R
Sbjct: 569 VEPQGDTSKNWSVFFNETGHYLSLKSQSRLD----QGEYNVVLR 608



 Score =  115 bits (276), Expect = 2e-23
 Identities = 123/433 (28%), Positives = 187/433 (43%), Gaps = 42/433 (9%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           +F+ID  SG +     LDRE+ A Y ++  AT     + ++        V + D NDN P
Sbjct: 145 IFKIDRLSGWINVTQQLDREEKASYKLVAHATGVDVNIVEK---PFEFIVTVTDQNDNKP 201

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA---IRYAIIGGNTQ----MQFS 201
            F++  +  +V E  ++    V   + ATDAD   N+    I YAII  +      + F+
Sbjct: 202 VFTQNPFNANVPE--ALEKGEVFMTVTATDADDKENTDNADISYAIISQDPPSAKPIMFA 259

Query: 202 IDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260
           I+ +SG +S+++T LD EQ   Y LVI A D      S T   +I + D NDNAP F  +
Sbjct: 260 INPVSGGISVLETGLDREQWSRYTLVITATDMNGEGGSTTGTAVITVMDSNDNAPLFEQT 319

Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNA--ELTYTMTDKDYTGNVDLPITIDPRSGWV 318
               SV EN  +G  +  +   D DE  +      Y +   D  G  ++        G +
Sbjct: 320 SHTVSVPEN-QVGAQVANLPVTDGDEPESTAWSTKYRVIGGDKGGFFNVSTGPSRLEGVI 378

Query: 319 YTSGQLDRETQAKYQLLVTATD-----GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373
            T   LD E   +Y L V   +     G  P  +AT T              F+P +  +
Sbjct: 379 TTVKPLDYEKTKQYILFVIVVNDDKFVGSLPTSTATVT---VNVEDVNEPPEFIPKEKFI 435

Query: 374 ELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431
              ED P G+ +V  TATD D +   ++ Y I   +  G  SIT     G I V   +D 
Sbjct: 436 SKPEDLPVGSNLVIYTATDVDTEKKQKITYRI-DYDPSGWLSITDS---GQIQVKTAMDR 491

Query: 432 K----QERRYVLTVSATDSGGRS---DTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484
           +    ++ +Y   + A D    S    T  + I + D N+ APV           E A  
Sbjct: 492 ESSNVKDGKYKALILALDDDVESPATGTGTLVIELQDVNDNAPVINERTIKLCNRESA-- 549

Query: 485 GTTVLVVSATDSD 497
              ++++S TD+D
Sbjct: 550 ---LVLLSITDND 559


>UniRef50_Q90Z37 Cluster: E-cadherin; n=19; Danio rerio|Rep:
           E-cadherin - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 864

 Score =  145 bits (352), Expect = 1e-32
 Identities = 129/466 (27%), Positives = 207/466 (44%), Gaps = 38/466 (8%)

Query: 163 ISVTDN---PVIAKIKATDADVGANSAIRYAIIGGNTQMQ----FSIDSLSGDVSLVKTL 215
           ISV++N   P   ++    +D    + + Y I G    +     F+ID LSG VS+ + L
Sbjct: 147 ISVSENSKGPFPMRLVQIKSDYAIETRLAYKITGEGADLDPKGIFTIDRLSGWVSVTQLL 206

Query: 216 DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275
           D E+  SY+L   A    +        +++ + D NDN P F  + F  +V E +  G  
Sbjct: 207 DREKKASYKLRAHANGVDADVTEKPMDIIVTVTDQNDNKPVFTQNPFNGNVPEALEKGEV 266

Query: 276 IVRVQAYDADEGV---NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ-LDRETQAK 331
            + V A DAD+     NA+++Y +  +D          I+P SG +    + LDRE   +
Sbjct: 267 FMTVTATDADDKENTDNADISYVIISQDPPSPKPNMFAINPVSGGISVLEKGLDREQWFR 326

Query: 332 YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTAT 391
           Y L++TATD      S T T              F    Y   + E++  G  V  L  T
Sbjct: 327 YTLVITATDMNGEGLSTTGTAVITVTDSNDNAPLFEQSSYTASVPENQ-VGVEVAKLPVT 385

Query: 392 DADEDN----RLHYEITGGNTRGRFSITSQNGR--GLITVAQPLDFKQERRYVLTVSATD 445
           D DE         Y+I  G+  G F+I++   R  G+IT  +PLD+++ ++Y+L+V   +
Sbjct: 386 DGDEPESTAWSTKYQIIAGDKGGFFNISTGPSRLEGIITTVKPLDYEKTKQYILSVIVVN 445

Query: 446 SGG-----RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500
                    + TA V +N+ D N   P F       S  E+ P+G+ ++  +A D D   
Sbjct: 446 DDKFVGPLPTSTATVTVNVKDVNE-PPEFIPKEKFISRPENLPVGSNLIPFTAIDPDTEK 504

Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS----GYLLTVTARDG 556
              ITY + ++ S+         ++    +G I     LDRE+ +     Y   + A D 
Sbjct: 505 KQNITYRIGNDPSD---------WLNITGSGQIQVKNALDRESSNVKDGKYKALILALDN 555

Query: 557 GVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601
            V S  + T  + I + DVNDN PV  ++       E A V  S++
Sbjct: 556 DVESPATGTGTLVIELQDVNDNAPVINERTIKLCNRESAPVLLSIT 601



 Score =  144 bits (350), Expect = 2e-32
 Identities = 133/439 (30%), Positives = 205/439 (46%), Gaps = 37/439 (8%)

Query: 396 DNRLHYEITGGNT----RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT--DSGGR 449
           + RL Y+ITG       +G F+I   +G   ++V Q LD +++  Y L   A   D+   
Sbjct: 171 ETRLAYKITGEGADLDPKGIFTIDRLSG--WVSVTQLLDREKKASYKLRAHANGVDADVT 228

Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN---AQITY 506
                + + +TD N+  PVF   P+  +V E    G   + V+ATD+D   N   A I+Y
Sbjct: 229 EKPMDIIVTVTDQNDNKPVFTQNPFNGNVPEALEKGEVFMTVTATDADDKENTDNADISY 288

Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAITT-NKLLDRETMSGYLLTVTARDGGVPSLSDTT 565
            +   IS +  +     F INP +G I+   K LDRE    Y L +TA D     LS T 
Sbjct: 289 VI---ISQDPPSPKPNMFAINPVSGGISVLEKGLDREQWFRYTLVITATDMNGEGLSTTG 345

Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV--GLNGRIHYELDPK 623
              I+V D NDN P+F+Q  YTA++ E+  VG  V+++  TD D          Y++   
Sbjct: 346 TAVITVTDSNDNAPLFEQSSYTASVPENQ-VGVEVAKLPVTDGDEPESTAWSTKYQIIAG 404

Query: 624 DREEGSFVIDPA----SGVIRTNKALDRESVATHDLKAVAIDGGT---PPQSSTVIVHIK 676
           D+  G F I        G+I T K LD E    + L  + ++      P  +ST  V + 
Sbjct: 405 DKG-GFFNISTGPSRLEGIITTVKPLDYEKTKQYILSVIVVNDDKFVGPLPTSTATVTVN 463

Query: 677 IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736
           ++D+N+ PP F          EN P+G+ +    A DPD      + Y I G D S+  +
Sbjct: 464 VKDVNE-PPEFIPKEKFISRPENLPVGSNLIPFTAIDPDTEKKQNITYRI-GNDPSDWLN 521

Query: 737 LETRQGSDKAELVTMVDLDYESPRK-KYELVIRA----ASPPLWNDVRVEILVTDVNDNA 791
           +    GS + ++   +D +  + +  KY+ +I A       P      + I + DVNDNA
Sbjct: 522 IT---GSGQIQVKNALDRESSNVKDGKYKALILALDNDVESPATGTGTLVIELQDVNDNA 578

Query: 792 PVMKDFQIIFNNYKDCFPV 810
           PV+ +  I   N ++  PV
Sbjct: 579 PVINERTIKLCN-RESAPV 596



 Score =  131 bits (317), Expect = 2e-28
 Identities = 128/473 (27%), Positives = 211/473 (44%), Gaps = 48/473 (10%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAE-VEYTIELVTADT 69
           + V D ND+ PVF    +  +V E    G   +T+ ATD D  +N +  + +  +++ D 
Sbjct: 236 VTVTDQNDNKPVFTQNPFNGNVPEALEKGEVFMTVTATDADDKENTDNADISYVIISQDP 295

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLVKATDQASPVSD 128
            +P+              ++F I+  SG + +    LDRE+  RYT+++ ATD      +
Sbjct: 296 PSPK-------------PNMFAINPVSGGISVLEKGLDREQWFRYTLVITATDMN---GE 339

Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA-- 186
            LS+T T  + + D NDN P F + +YT SV E+    +   +AK+  TD D   ++A  
Sbjct: 340 GLSTTGTAVITVTDSNDNAPLFEQSSYTASVPENQVGVE---VAKLPVTDGDEPESTAWS 396

Query: 187 IRYAIIGGNTQMQFSIDS----LSGDVSLVKTLDYEQVRSYRL-VIRAQDGG--SPSRSN 239
            +Y II G+    F+I +    L G ++ VK LDYE+ + Y L VI   D     P  ++
Sbjct: 397 TKYQIIAGDKGGFFNISTGPSRLEGIITTVKPLDYEKTKQYILSVIVVNDDKFVGPLPTS 456

Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299
           T  + +N++DVN+  P F       S  EN+P+G +++   A D D      +TY +   
Sbjct: 457 TATVTVNVKDVNE-PPEFIPKEKFISRPENLPVGSNLIPFTAIDPDTEKKQNITYRI--- 512

Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRET----QAKYQLLVTATDGGDPPRSATATXXXX 355
              GN          SG +     LDRE+      KY+ L+ A D  D    AT T    
Sbjct: 513 ---GNDPSDWLNITGSGQIQVKNALDRESSNVKDGKYKALILALD-NDVESPATGTGTLV 568

Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD-EDNRLHYEI-TGGNTRGRFS 413
                      +  +  ++L   E    PV+ L+ TD D       +++   G+T   +S
Sbjct: 569 IELQDVNDNAPVINERTIKLCNRE--SAPVL-LSITDKDLPPFAGPFKVEPQGDTSKNWS 625

Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYA 466
           +   N  G     +P    ++  Y + +   D  G S   ++Q ++ D    A
Sbjct: 626 VFF-NETGHFLNIKPQSQLEQGEYKVVLRVADREGESQENIIQASVCDCKGEA 677



 Score =  124 bits (298), Expect = 5e-26
 Identities = 132/475 (27%), Positives = 206/475 (43%), Gaps = 32/475 (6%)

Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324
           SVSEN   G   +R+    +D  +   L Y +T +    +     TID  SGWV  +  L
Sbjct: 148 SVSENSK-GPFPMRLVQIKSDYAIETRLAYKITGEGADLDPKGIFTIDRLSGWVSVTQLL 206

Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384
           DRE +A Y+L   A                           F    +   + E    G  
Sbjct: 207 DREKKASYKLRAHANGVDADVTEKPMDIIVTVTDQNDNKPVFTQNPFNGNVPEALEKGEV 266

Query: 385 VVTLTATDADE----DNR-LHYEITGGNTRG----RFSITSQNGRGLITVAQPLDFKQER 435
            +T+TATDAD+    DN  + Y I   +        F+I   +G G+  + + LD +Q  
Sbjct: 267 FMTVTATDADDKENTDNADISYVIISQDPPSPKPNMFAINPVSG-GISVLEKGLDREQWF 325

Query: 436 RYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493
           RY L ++ATD  G   S T    I +TD+N+ AP+FE + YTASV E+  +G  V  +  
Sbjct: 326 RYTLVITATDMNGEGLSTTGTAVITVTDSNDNAPLFEQSSYTASVPENQ-VGVEVAKLPV 384

Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553
           TD D   +   +      I+ +     +     +   G ITT K LD E    Y+L+V  
Sbjct: 385 TDGDEPESTAWSTKYQI-IAGDKGGFFNISTGPSRLEGIITTVKPLDYEKTKQYILSVIV 443

Query: 554 RDGGV---PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610
            +      P  + T  V ++V DVN+      ++ + +   E+  VG+++    A D D 
Sbjct: 444 VNDDKFVGPLPTSTATVTVNVKDVNEPPEFIPKEKFISR-PENLPVGSNLIPFTAIDPDT 502

Query: 611 GLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK----AVAIDGGT 664
                I Y +  DP D     ++    SG I+   ALDRES    D K     +A+D   
Sbjct: 503 EKKQNITYRIGNDPSD-----WLNITGSGQIQVKNALDRESSNVKDGKYKALILALDNDV 557

Query: 665 P-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718
             P + T  + I+++D+ND+ PV     +     E++P+  +I + +   P  GP
Sbjct: 558 ESPATGTGTLVIELQDVNDNAPVINERTIKLCNRESAPVLLSITD-KDLPPFAGP 611



 Score =  116 bits (280), Expect = 7e-24
 Identities = 118/429 (27%), Positives = 180/429 (41%), Gaps = 32/429 (7%)

Query: 89  VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148
           +F ID  SG +     LDREK A Y +   A    + V+++      I V + D NDN P
Sbjct: 190 IFTIDRLSGWVSVTQLLDREKKASYKLRAHANGVDADVTEK---PMDIIVTVTDQNDNKP 246

Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA---NSAIRYAIIGGNTQM----QFS 201
            F++  +  +V E  ++    V   + ATDAD      N+ I Y II  +        F+
Sbjct: 247 VFTQNPFNGNVPE--ALEKGEVFMTVTATDADDKENTDNADISYVIISQDPPSPKPNMFA 304

Query: 202 IDSLSGDVS-LVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260
           I+ +SG +S L K LD EQ   Y LVI A D      S T   +I + D NDNAP F  S
Sbjct: 305 INPVSGGISVLEKGLDREQWFRYTLVITATDMNGEGLSTTGTAVITVTDSNDNAPLFEQS 364

Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNA--ELTYTMTDKDYTGNVDLPITIDPRSGWV 318
            +  SV EN  +G  + ++   D DE  +      Y +   D  G  ++        G +
Sbjct: 365 SYTASVPEN-QVGVEVAKLPVTDGDEPESTAWSTKYQIIAGDKGGFFNISTGPSRLEGII 423

Query: 319 YTSGQLDRETQAKY--QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376
            T   LD E   +Y   ++V   D    P   +                F+P +  +   
Sbjct: 424 TTVKPLDYEKTKQYILSVIVVNDDKFVGPLPTSTATVTVNVKDVNEPPEFIPKEKFISRP 483

Query: 377 EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK---- 432
           E+ P G+ ++  TA D D + + +     GN    +   +  G G I V   LD +    
Sbjct: 484 ENLPVGSNLIPFTAIDPDTEKKQNITYRIGNDPSDW--LNITGSGQIQVKNALDRESSNV 541

Query: 433 QERRYVLTVSATDSGGRS---DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489
           ++ +Y   + A D+   S    T  + I + D N+ APV           E AP+     
Sbjct: 542 KDGKYKALILALDNDVESPATGTGTLVIELQDVNDNAPVINERTIKLCNRESAPV----- 596

Query: 490 VVSATDSDV 498
           ++S TD D+
Sbjct: 597 LLSITDKDL 605



 Score =  109 bits (261), Expect = 1e-21
 Identities = 100/354 (28%), Positives = 148/354 (41%), Gaps = 25/354 (7%)

Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555
           SD  I  ++ Y ++ E    A       F I+  +G ++  +LLDRE  + Y L   A  
Sbjct: 166 SDYAIETRLAYKITGE---GADLDPKGIFTIDRLSGWVSVTQLLDREKKASYKLRAHANG 222

Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL--- 612
                     D+ ++V D NDN+PVF Q  +  N+ E    G     V ATDAD      
Sbjct: 223 VDADVTEKPMDIIVTVTDQNDNKPVFTQNPFNGNVPEALEKGEVFMTVTATDADDKENTD 282

Query: 613 NGRIHYEL---DPKDREEGSFVIDPASGVIRT-NKALDRESVATHDLKAVAIDGGTPPQS 668
           N  I Y +   DP   +   F I+P SG I    K LDRE    + L   A D      S
Sbjct: 283 NADISYVIISQDPPSPKPNMFAINPVSGGISVLEKGLDREQWFRYTLVITATDMNGEGLS 342

Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV--VHYSI 726
           +T    I + D ND+ P+FE    T  + EN  +G  + ++   D DE  +      Y I
Sbjct: 343 TTGTAVITVTDSNDNAPLFEQSSYTASVPENQ-VGVEVAKLPVTDGDEPESTAWSTKYQI 401

Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI-----RAASPPLWNDVRVE 781
             GD    F++ T     +  + T+  LDYE  ++    VI     +   P   +   V 
Sbjct: 402 IAGDKGGFFNISTGPSRLEGIITTVKPLDYEKTKQYILSVIVVNDDKFVGPLPTSTATVT 461

Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVG----PFGRVPAYDADVTDKLQYRI 831
           + V DVN+    +   + I  +  +  PVG    PF  +   D +    + YRI
Sbjct: 462 VNVKDVNEPPEFIPKEKFI--SRPENLPVGSNLIPFTAIDP-DTEKKQNITYRI 512


>UniRef50_Q7PQL1 Cluster: ENSANGP00000011254; n=2; Culicidae|Rep:
            ENSANGP00000011254 - Anopheles gambiae str. PEST
          Length = 1821

 Score =  144 bits (350), Expect = 2e-32
 Identities = 166/570 (29%), Positives = 253/570 (44%), Gaps = 87/570 (15%)

Query: 370  QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITG------GNTRGRFSITSQNGRG 421
            Q +  L E+   G  +  LTA D D  +++++ YE+ G      G     F I   NG  
Sbjct: 1097 QLKFALPENVEVGKVIFKLTANDDDFEKNSKVFYEVVGQTELNSGERVSYFRIDRNNGE- 1155

Query: 422  LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481
             + VA  L    E    L ++A D GG SD   VQ  + D N+ APVFE   YT +V E 
Sbjct: 1156 -LRVANRLP--PETDVKLNITAKDVGGLSDMLQVQFRVYDVNDNAPVFEKQWYTFNVDEG 1212

Query: 482  A-PI-GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539
            + PI G  +  V A D D G+N  +TY L ++   +        F I+P  G I  +  +
Sbjct: 1213 SYPITGKKIGQVRANDEDTGMNGNVTYMLITDGDQKI------PFSISPLDGTIRVSGEI 1266

Query: 540  DRETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVF--------------KQQ 584
            DRE ++ Y   V A D      LS   DVE+ V+D NDN P F              +  
Sbjct: 1267 DREMIASYRFRVLASDNNFDLKLSAMVDVEVIVMDRNDNNPEFTAYDDLRSDRNNIKRLP 1326

Query: 585  LYTANIMEDALVGTSVSQVGATDADVGLNGR--IHYELDPKDREEGSFVIDPASGVIRT- 641
            +Y A +  +A VGT V QV A D+D   NG   + Y L  +  +   F IDP  GV+ T 
Sbjct: 1327 VYVAYLDVNAKVGTFVKQVMARDSDFRENGNGLVIYSLTGQS-DVLQFSIDPKDGVVTTA 1385

Query: 642  -----NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE-------DINDSPPVFES 689
                 ++A  R++    ++  VA D GTPP+SS  ++ + ++        + + PP+F  
Sbjct: 1386 SKFTPSEAGTRKTYEHLNVTVVASDFGTPPRSSMALLIVNLQGDTLQQHPVEERPPLFPY 1445

Query: 690  DCLTFYISENSP-----IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS- 743
                  + EN P     +  T+ +  A+DP         + I G    + F ++ R GS 
Sbjct: 1446 KYYEIELRENDPAPRIVLNVTLSKRYANDP-------FRWEIVGDTFDDQFRIDERNGSL 1498

Query: 744  ------DKAE------LVTMVDLDYES---PRKKYEL--VIRAASPPLW-NDVRVEILVT 785
                  D+ E       + +  +  E+   P   Y L   ++  S  L+ N+V + I V 
Sbjct: 1499 WLLRPLDREERDSYDVRIRVQKIKRETRNIPSVLYALENPVKRKSHRLFDNEVEIMIKVV 1558

Query: 786  DVNDNAPVMKD-FQIIFNNYKDCFPVG-PFGRVPAYDADV--TDKLQYRILSGNNANLIL 841
            DVNDNAPV +D +  I +   D    G    +V A D D     +++Y +L+     L  
Sbjct: 1559 DVNDNAPVFRDNYGPIISVVPDTANYGYAVMKVEATDDDAGSNGEVRYTLLN-EPPRLFA 1617

Query: 842  LNETTGSMTLSPQLNTNVPKLATMEVSVTD 871
            ++  TG + L   L +   K+   +V  TD
Sbjct: 1618 IDSLTGQIRLLNSLASFKEKVFGFDVKATD 1647



 Score =  140 bits (340), Expect = 4e-31
 Identities = 159/650 (24%), Positives = 274/650 (42%), Gaps = 51/650 (7%)

Query: 106 DREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISV 165
           D + + +++V    T   S   D  SS  TI V I D NDN P+F    Y V++DE   +
Sbjct: 83  DPQSILKFSVFCSGTSATSAKQDN-SSFFTITVYIEDINDNDPEFINLPYVVTLDESTPI 141

Query: 166 TDNPVIAKIKATDADV--GANSAIRYAIIGGNTQ---MQFSID-SLSGDVSLVKTLDYEQ 219
            +  V  +IKA D D     NS + YA+   + +     F ++ S    + L + LDY+ 
Sbjct: 142 -ETVVFNRIKAIDRDKPNTPNSDLEYALAAKHMKSGDFPFRLEGSQRPSLVLQRALDYDA 200

Query: 220 -VRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIG----- 273
             RS  + I A D G+P R+    + +N+RDV+D  P F  + ++  + E+ P+      
Sbjct: 201 GWRSMSVQIVASDRGNPPRTANATIRVNLRDVDDLPPIFTRAQYRTRIKESFPLTGKPIH 260

Query: 274 ---YSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA 330
              Y    + A+D D  +N  L Y +      GN      I P +G ++   ++D ++++
Sbjct: 261 IPLYIEPPIMAFDQD-SLNETLVYGIV----AGNERQLFWISPETGVLFLQKEIDLDSES 315

Query: 331 ----KYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386
                + L + A    DP +SA A               F    Y + + E+ P G  ++
Sbjct: 316 LPDNTFTLQIEAQQINDPTKSAFARVDIEVIDLNDNVPEFEVDLYNISIIENLPKGFSIL 375

Query: 387 TLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444
            + A D D  E+   +Y +     +G F I   +G  ++     LD +Q     + V A 
Sbjct: 376 QVNAIDRDQGENAEFYYYLMDEEPKGAFMIDHGSGWIVVRDETFLDKEQRSSLKMNVHAV 435

Query: 445 DSGGRSDTA------MVQINITDANNYAPVFENAP-YTASVFEDAPIGTTVLVVSATDSD 497
           +   + D +       V+I + D N+  P FE    Y      +A IG+ V  + A D D
Sbjct: 436 ERVEQYDRSRNYGKVQVEITLLDTNDNTPEFEQGTLYEFKTHCNASIGSKVGQIRALDPD 495

Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG 557
              N +I YS+ +   N  +      F+++P TG I  ++ L   T       V ARD  
Sbjct: 496 DLGNGKIQYSIKNVRPNLVI-----PFLLDPDTGDIRVSEAL---TYGKIAFFVEARDQP 547

Query: 558 V-PSLS--DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614
             PS S  +   V I +V  +  +  F    Y   +  DA +G+SV Q+  T  D+  + 
Sbjct: 548 QNPSESRFNVALVTIDIVCQSIEDIEFIGAPYEFWVGADAAIGSSVGQI-RTTFDMVSDE 606

Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674
            I ++L     E   F I+  SG++   +++++     ++ + V      P  +   +  
Sbjct: 607 EIFFDLLHSYPEGVPFAIEERSGIVTVIESMEKFDRRCYEFETVV--SYLPDSAGKNVEQ 664

Query: 675 IKIEDINDSPPVFESDCLTFYISENSPI--GTTIGEIRAHDPDEGPNAVV 722
           +  E  N    +  ++     I  N  +  GT    I     +  PN ++
Sbjct: 665 LTPEAYNSLEKIIVTNVTIHVIKHNFMLLRGTNATPIEFRVKENKPNTMI 714



 Score =  137 bits (331), Expect = 5e-30
 Identities = 159/609 (26%), Positives = 249/609 (40%), Gaps = 92/609 (15%)

Query: 22   VFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXX 81
            V +  Q + ++ E    G  +  L A D D  KN++V Y  E+V    LN  +       
Sbjct: 1092 VAKKSQLKFALPENVEVGKVIFKLTANDDDFEKNSKVFY--EVVGQTELNSGERVSY--- 1146

Query: 82   XXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNII 141
                    FRID  +G L     L  E   +  +  K       +SD L     +   + 
Sbjct: 1147 --------FRIDRNNGELRVANRLPPETDVKLNITAK---DVGGLSDMLQ----VQFRVY 1191

Query: 142  DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII-GGNTQMQF 200
            D NDN P F ++ YT +VDE         I +++A D D G N  + Y +I  G+ ++ F
Sbjct: 1192 DVNDNAPVFEKQWYTFNVDEGSYPITGKKIGQVRANDEDTGMNGNVTYMLITDGDQKIPF 1251

Query: 201  SIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR-SNTTQLLINIRDVNDNAPRF-- 257
            SI  L G + +   +D E + SYR  + A D     + S    + + + D NDN P F  
Sbjct: 1252 SISPLDGTIRVSGEIDREMIASYRFRVLASDNNFDLKLSAMVDVEVIVMDRNDNNPEFTA 1311

Query: 258  YTSL------------FQESVSENVPIGYSIVRVQAYDAD--EGVNAELTYTMTDKDYTG 303
            Y  L            +   +  N  +G  + +V A D+D  E  N  + Y++T +    
Sbjct: 1312 YDDLRSDRNNIKRLPVYVAYLDVNAKVGTFVKQVMARDSDFRENGNGLVIYSLTGQSDV- 1370

Query: 304  NVDLPITIDPRSGWVYTSGQL------DRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357
               L  +IDP+ G V T+ +        R+T     + V A+D G PPRS+ A       
Sbjct: 1371 ---LQFSIDPKDGVVTTASKFTPSEAGTRKTYEHLNVTVVASDFGTPPRSSMALLIVNLQ 1427

Query: 358  XXXXXXX-------XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG 410
                           F    YE+EL E++P    V+ +T +    ++   +EI G     
Sbjct: 1428 GDTLQQHPVEERPPLFPYKYYEIELRENDPAPRIVLNVTLSKRYANDPFRWEIVGDTFDD 1487

Query: 411  RFSITSQNGRGLITVAQPLD---------------FKQERR------YVLTVSATDSGGR 449
            +F I  +NG   + + +PLD                K+E R      Y L         R
Sbjct: 1488 QFRIDERNGS--LWLLRPLDREERDSYDVRIRVQKIKRETRNIPSVLYALENPVKRKSHR 1545

Query: 450  --SDTAMVQINITDANNYAPVFEN--APYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505
               +   + I + D N+ APVF +   P  + V + A  G  V+ V ATD D G N ++ 
Sbjct: 1546 LFDNEVEIMIKVVDVNDNAPVFRDNYGPIISVVPDTANYGYAVMKVEATDDDAGSNGEVR 1605

Query: 506  YSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKLLD-RETMSGYLLTVTARDGGVPSLSD 563
            Y+L +E          + F I+  TG I   N L   +E + G+ +  T R+G     S 
Sbjct: 1606 YTLLNE--------PPRLFAIDSLTGQIRLLNSLASFKEKVFGFDVKATDREGADDGKST 1657

Query: 564  TTDVEISVV 572
              +V + V+
Sbjct: 1658 IANVFVYVL 1666



 Score =  133 bits (322), Expect = 6e-29
 Identities = 114/379 (30%), Positives = 184/379 (48%), Gaps = 24/379 (6%)

Query: 371 YEVELAEDEPPGTPVVT-LTATDADEDNR----LHYEITGGNTR-GRFSITSQNG-RGLI 423
           Y V L E  P  T V   + A D D+ N     L Y +   + + G F    +   R  +
Sbjct: 131 YVVTLDESTPIETVVFNRIKAIDRDKPNTPNSDLEYALAAKHMKSGDFPFRLEGSQRPSL 190

Query: 424 TVAQPLDFKQERRYV-LTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480
            + + LD+    R + + + A+D G   R+  A +++N+ D ++  P+F  A Y   + E
Sbjct: 191 VLQRALDYDAGWRSMSVQIVASDRGNPPRTANATIRVNLRDVDDLPPIFTRAQYRTRIKE 250

Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ-FVINPQTGAITTNKLL 539
             P+    + +     +  I A    SL+  +    VA +++Q F I+P+TG +   K +
Sbjct: 251 SFPLTGKPIHIPLY-IEPPIMAFDQDSLNETLVYGIVAGNERQLFWISPETGVLFLQKEI 309

Query: 540 DRETMS----GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595
           D ++ S     + L + A+    P+ S    V+I V+D+NDN P F+  LY  +I+E+  
Sbjct: 310 DLDSESLPDNTFTLQIEAQQINDPTKSAFARVDIEVIDLNDNVPEFEVDLYNISIIENLP 369

Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG--VIRTNKALDRESVATH 653
            G S+ QV A D D G N   +Y L   +  +G+F+ID  SG  V+R    LD+E  ++ 
Sbjct: 370 KGFSILQVNAIDRDQGENAEFYYYL-MDEEPKGAFMIDHGSGWIVVRDETFLDKEQRSSL 428

Query: 654 DLKAVAIDGGTPPQSS----TVIVHIKIEDINDSPPVFESDCL-TFYISENSPIGTTIGE 708
            +   A++       S     V V I + D ND+ P FE   L  F    N+ IG+ +G+
Sbjct: 429 KMNVHAVERVEQYDRSRNYGKVQVEITLLDTNDNTPEFEQGTLYEFKTHCNASIGSKVGQ 488

Query: 709 IRAHDPDEGPNAVVHYSIK 727
           IRA DPD+  N  + YSIK
Sbjct: 489 IRALDPDDLGNGKIQYSIK 507



 Score =  120 bits (289), Expect = 6e-25
 Identities = 134/510 (26%), Positives = 221/510 (43%), Gaps = 50/510 (9%)

Query: 11  INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-LKATDQDIGK--NAEVEYTIELVTA 67
           + + D ND+ P F    Y  ++ E     T V   +KA D+D     N+++EY +    A
Sbjct: 114 VYIEDINDNDPEFINLPYVVTLDESTPIETVVFNRIKAIDRDKPNTPNSDLEYAL---AA 170

Query: 68  DTLNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVAR-YTVLVKATDQASP 125
             +   D               FR++G +  +L+ + +LD +   R  +V + A+D+ +P
Sbjct: 171 KHMKSGDFP-------------FRLEGSQRPSLVLQRALDYDAGWRSMSVQIVASDRGNP 217

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK------IKATDA 179
                ++ ATI VN+ D +D  P F+   Y   + E   +T  P+         I A D 
Sbjct: 218 PR---TANATIRVNLRDVDDLPPIFTRAQYRTRIKESFPLTGKPIHIPLYIEPPIMAFDQ 274

Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV----RSYRLVIRAQDGGSP 235
           D   N  + Y I+ GN +  F I   +G + L K +D +       ++ L I AQ    P
Sbjct: 275 D-SLNETLVYGIVAGNERQLFWISPETGVLFLQKEIDLDSESLPDNTFTLQIEAQQINDP 333

Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295
           ++S   ++ I + D+NDN P F   L+  S+ EN+P G+SI++V A D D+G NAE  Y 
Sbjct: 334 TKSAFARVDIEVIDLNDNVPEFEVDLYNISIIENLPKGFSILQVNAIDRDQGENAEFYYY 393

Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGGDP-PRS---AT 349
           + D++  G       ID  SGW+    +  LD+E ++  ++ V A +  +   RS     
Sbjct: 394 LMDEEPKG----AFMIDHGSGWIVVRDETFLDKEQRSSLKMNVHAVERVEQYDRSRNYGK 449

Query: 350 ATXXXXXXXXXXXXXXFMPGQ-YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGG 406
                           F  G  YE +   +   G+ V  + A D D+  + ++ Y I   
Sbjct: 450 VQVEITLLDTNDNTPEFEQGTLYEFKTHCNASIGSKVGQIRALDPDDLGNGKIQYSIKNV 509

Query: 407 NTRGRFSITSQNGRGLITVAQPLDFKQERRYV--LTVSATDSGGRSDTAMVQINITDANN 464
                         G I V++ L + +   +V         S  R + A+V I+I   + 
Sbjct: 510 RPNLVIPFLLDPDTGDIRVSEALTYGKIAFFVEARDQPQNPSESRFNVALVTIDIVCQSI 569

Query: 465 YAPVFENAPYTASVFEDAPIGTTVLVVSAT 494
               F  APY   V  DA IG++V  +  T
Sbjct: 570 EDIEFIGAPYEFWVGADAAIGSSVGQIRTT 599



 Score =  116 bits (279), Expect = 9e-24
 Identities = 155/576 (26%), Positives = 243/576 (42%), Gaps = 89/576 (15%)

Query: 170  VIAKIKATDADVGANSAIRYAIIG------GNTQMQFSIDSLSGDVSLVKTLDYEQVRSY 223
            VI K+ A D D   NS + Y ++G      G     F ID  +G++ +   L  E     
Sbjct: 1111 VIFKLTANDDDFEKNSKVFYEVVGQTELNSGERVSYFRIDRNNGELRVANRLPPET--DV 1168

Query: 224  RLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE-NVPI-GYSIVRVQA 281
            +L I A+D G    S+  Q+   + DVNDNAP F    +  +V E + PI G  I +V+A
Sbjct: 1169 KLNITAKDVGG--LSDMLQVQFRVYDVNDNAPVFEKQWYTFNVDEGSYPITGKKIGQVRA 1226

Query: 282  YDADEGVNAELTYTM-TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD 340
             D D G+N  +TY + TD    G+  +P +I P  G +  SG++DRE  A Y+  V A+D
Sbjct: 1227 NDEDTGMNGNVTYMLITD----GDQKIPFSISPLDGTIRVSGEIDREMIASYRFRVLASD 1282

Query: 341  GG-DPPRSATATXXXXXXXXXXXXXXFMPGQ--------------YEVELAEDEPPGTPV 385
               D   SA                 F                  Y   L  +   GT V
Sbjct: 1283 NNFDLKLSAMVDVEVIVMDRNDNNPEFTAYDDLRSDRNNIKRLPVYVAYLDVNAKVGTFV 1342

Query: 386  VTLTATDAD----EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ---PLDFKQERRYV 438
              + A D+D     +  + Y +TG +   +FSI  ++G  ++T A    P +    + Y 
Sbjct: 1343 KQVMARDSDFRENGNGLVIYSLTGQSDVLQFSIDPKDG--VVTTASKFTPSEAGTRKTYE 1400

Query: 439  ---LTVSATDSGG--RSDTAMVQINIT-DANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492
               +TV A+D G   RS  A++ +N+  D     PV E  P     + +         + 
Sbjct: 1401 HLNVTVVASDFGTPPRSSMALLIVNLQGDTLQQHPVEERPPLFPYKYYE---------IE 1451

Query: 493  ATDSDVGINAQITYSLSSEISNEAVAHH------DQQFVINPQTGAITTNKLLDRETMSG 546
              ++D      +  +LS   +N+           D QF I+ + G++   + LDRE    
Sbjct: 1452 LRENDPAPRIVLNVTLSKRYANDPFRWEIVGDTFDDQFRIDERNGSLWLLRPLDREERDS 1511

Query: 547  YLLTVTARD-----GGVPSL----------------SDTTDVEISVVDVNDNEPVFKQQL 585
            Y + +  +        +PS+                 +  ++ I VVDVNDN PVF+   
Sbjct: 1512 YDVRIRVQKIKRETRNIPSVLYALENPVKRKSHRLFDNEVEIMIKVVDVNDNAPVFRDNY 1571

Query: 586  --YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK 643
                + + + A  G +V +V ATD D G NG + Y L   +     F ID  +G IR   
Sbjct: 1572 GPIISVVPDTANYGYAVMKVEATDDDAGSNGEVRYTL--LNEPPRLFAIDSLTGQIRLLN 1629

Query: 644  ALD--RESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677
            +L   +E V   D+KA   +G    +S+   V + +
Sbjct: 1630 SLASFKEKVFGFDVKATDREGADDGKSTIANVFVYV 1665



 Score =  109 bits (263), Expect = 8e-22
 Identities = 134/520 (25%), Positives = 218/520 (41%), Gaps = 44/520 (8%)

Query: 373 VELAEDEPPGTPVVTLTATDADE------DNRLHYE---ITGGNTRGRFSITSQNGRGLI 423
           + L ED P G  +V+L A   +       +N   YE   +   N+     I +++  GL+
Sbjct: 20  LRLKEDFPVGGEIVSLYAYPRNSILIPRTENSSDYEYFKLKEINSTVVSVILNRSLDGLV 79

Query: 424 TVAQPLDFKQERRYVLTVSATDSG-GRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482
               P    +   +    SAT +    S    + + I D N+  P F N PY  ++ E  
Sbjct: 80  DSDDPQSILKFSVFCSGTSATSAKQDNSSFFTITVYIEDINDNDPEFINLPYVVTLDEST 139

Query: 483 PIGTTVLV-VSATDSDVGI--NAQITYSLSSEISNEAVAHHDQQFVIN-PQTGAITTNKL 538
           PI T V   + A D D     N+ + Y+L+++         D  F +   Q  ++   + 
Sbjct: 140 PIETVVFNRIKAIDRDKPNTPNSDLEYALAAKHMKSG----DFPFRLEGSQRPSLVLQRA 195

Query: 539 LDRET-MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED-ALV 596
           LD +       + + A D G P  +    + +++ DV+D  P+F +  Y   I E   L 
Sbjct: 196 LDYDAGWRSMSVQIVASDRGNPPRTANATIRVNLRDVDDLPPIFTRAQYRTRIKESFPLT 255

Query: 597 GTSVS-------QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES 649
           G  +         + A D D  LN  + Y +     E   F I P +GV+   K +D +S
Sbjct: 256 GKPIHIPLYIEPPIMAFDQD-SLNETLVYGI-VAGNERQLFWISPETGVLFLQKEIDLDS 313

Query: 650 VATHD----LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705
            +  D    L+  A     P +S+   V I++ D+ND+ P FE D     I EN P G +
Sbjct: 314 ESLPDNTFTLQIEAQQINDPTKSAFARVDIEVIDLNDNVPEFEVDLYNISIIENLPKGFS 373

Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK---- 761
           I ++ A D D+G NA  +Y +   +   +F ++   G       T +D +  S  K    
Sbjct: 374 ILQVNAIDRDQGENAEFYYYLMDEEPKGAFMIDHGSGWIVVRDETFLDKEQRSSLKMNVH 433

Query: 762 KYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQII-FNNYKDCFPVGPFGRVPAYD 820
             E V +      +  V+VEI + D NDN P  +   +  F  + +       G++ A D
Sbjct: 434 AVERVEQYDRSRNYGKVQVEITLLDTNDNTPEFEQGTLYEFKTHCNASIGSKVGQIRALD 493

Query: 821 AD--VTDKLQYRILSGNNANLI---LLNETTGSMTLSPQL 855
            D     K+QY I      NL+   LL+  TG + +S  L
Sbjct: 494 PDDLGNGKIQYSI-KNVRPNLVIPFLLDPDTGDIRVSEAL 532



 Score = 95.5 bits (227), Expect = 2e-17
 Identities = 104/440 (23%), Positives = 182/440 (41%), Gaps = 35/440 (7%)

Query: 10  QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           ++N+ D +D  P+F   QY   ++E         +   T + I     +E  I     D+
Sbjct: 226 RVNLRDVDDLPPIFTRAQYRTRIKE---------SFPLTGKPIHIPLYIEPPIMAFDQDS 276

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
           LN               + +F I   +G L  +  +D +  +          +A  ++D 
Sbjct: 277 LN---ETLVYGIVAGNERQLFWISPETGVLFLQKEIDLDSESLPDNTFTLQIEAQQINDP 333

Query: 130 LSST-ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188
             S  A + + +ID NDN P+F    Y +S+ E++    +  I ++ A D D G N+   
Sbjct: 334 TKSAFARVDIEVIDLNDNVPEFEVDLYNISIIENLPKGFS--ILQVNAIDRDQGENAEFY 391

Query: 189 YAIIGGNTQMQFSIDSLSGDVSL--VKTLDYEQVRSYRL----VIRAQDGGSPSRSNTTQ 242
           Y ++    +  F ID  SG + +     LD EQ  S ++    V R +           Q
Sbjct: 392 YYLMDEEPKGAFMIDHGSGWIVVRDETFLDKEQRSSLKMNVHAVERVEQYDRSRNYGKVQ 451

Query: 243 LLINIRDVNDNAPRF-YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301
           + I + D NDN P F   +L++     N  IG  + +++A D D+  N ++ Y++  K+ 
Sbjct: 452 VEITLLDTNDNTPEFEQGTLYEFKTHCNASIGSKVGQIRALDPDDLGNGKIQYSI--KNV 509

Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP---RSATATXXXXXXX 358
             N+ +P  +DP +G +  S  L   T  K    V A D    P   R   A        
Sbjct: 510 RPNLVIPFLLDPDTGDIRVSEAL---TYGKIAFFVEARDQPQNPSESRFNVALVTIDIVC 566

Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTAT-DADEDNRLHYEITGGNTRG-RFSITS 416
                  F+   YE  +  D   G+ V  +  T D   D  + +++      G  F+I  
Sbjct: 567 QSIEDIEFIGAPYEFWVGADAAIGSSVGQIRTTFDMVSDEEIFFDLLHSYPEGVPFAIEE 626

Query: 417 QNGRGLITVAQPLDFKQERR 436
           ++  G++TV + ++ K +RR
Sbjct: 627 RS--GIVTVIESME-KFDRR 643



 Score = 83.0 bits (196), Expect = 1e-13
 Identities = 88/356 (24%), Positives = 150/356 (42%), Gaps = 55/356 (15%)

Query: 10   QINVLDCNDHSPVFEMQQYEASVREGA--SSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67
            Q  V D ND++PVFE Q Y  +V EG+   +G  +  ++A D+D G N  V Y + +   
Sbjct: 1187 QFRVYDVNDNAPVFEKQWYTFNVDEGSYPITGKKIGQVRANDEDTGMNGNVTYML-ITDG 1245

Query: 68   DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127
            D   P                 F I    G +     +DRE +A Y   V A+D    + 
Sbjct: 1246 DQKIP-----------------FSISPLDGTIRVSGEIDREMIASYRFRVLASDNNFDL- 1287

Query: 128  DRLSSTATIHVNIIDDNDNYPQFSE-----------KTYTVSVDE-DISVTDNPVIAKIK 175
             +LS+   + V ++D NDN P+F+            K   V V   D++      + ++ 
Sbjct: 1288 -KLSAMVDVEVIVMDRNDNNPEFTAYDDLRSDRNNIKRLPVYVAYLDVNAKVGTFVKQVM 1346

Query: 176  ATDADV--GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV---RSY---RLVI 227
            A D+D     N  + Y++ G +  +QFSID   G V+        +    ++Y    + +
Sbjct: 1347 ARDSDFRENGNGLVIYSLTGQSDVLQFSIDPKDGVVTTASKFTPSEAGTRKTYEHLNVTV 1406

Query: 228  RAQDGGSPSRSNTTQLLINIR-------DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQ 280
             A D G+P RS+   L++N++        V +  P F    ++  + EN P    ++ V 
Sbjct: 1407 VASDFGTPPRSSMALLIVNLQGDTLQQHPVEERPPLFPYKYYEIELRENDPAPRIVLNVT 1466

Query: 281  AYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLV 336
               +    N    + +    +    D    ID R+G ++    LDRE +  Y + +
Sbjct: 1467 L--SKRYANDPFRWEIVGDTF----DDQFRIDERNGSLWLLRPLDREERDSYDVRI 1516



 Score = 72.5 bits (170), Expect = 2e-10
 Identities = 98/380 (25%), Positives = 157/380 (41%), Gaps = 55/380 (14%)

Query: 429  LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488
            LD ++     L + ATD         ++I I D N+ APVFE      ++F  +      
Sbjct: 967  LDREEIESLTLKMMATDRDNLMSEVELKILILDVNDCAPVFERI----AIFRKS---RCE 1019

Query: 489  LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE--TMSG 546
            ++ + +D ++    +I   +  E  +  +   + +       G++  N+  DRE  TM  
Sbjct: 1020 MIENTSDLELMYLDEIETEVLPEFLDAGLMEMNSRV----SYGSVMVNRTADREHLTMRR 1075

Query: 547  YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606
             L     R  G                 N      K QL  A + E+  VG  + ++ A 
Sbjct: 1076 KLYKQKVRQRGR----------------NTRAVAKKSQLKFA-LPENVEVGKVIFKLTAN 1118

Query: 607  DADVGLNGRIHYEL----DPKDREEGS-FVIDPASGVIRTNKALDRESVATHDLKAVAID 661
            D D   N ++ YE+    +    E  S F ID  +G +R    L  E+    ++ A  + 
Sbjct: 1119 DDDFEKNSKVFYEVVGQTELNSGERVSYFRIDRNNGELRVANRLPPETDVKLNITAKDVG 1178

Query: 662  GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS-PI-GTTIGEIRAHDPDEGPN 719
            G     S  + V  ++ D+ND+ PVFE    TF + E S PI G  IG++RA+D D G N
Sbjct: 1179 G----LSDMLQVQFRVYDVNDNAPVFEKQWYTFNVDEGSYPITGKKIGQVRANDEDTGMN 1234

Query: 720  AVVHYS-IKGGDDSNSFSLETRQGSDKA------ELVTMVDLDYESPRKKYELVIRAASP 772
              V Y  I  GD    FS+    G+ +       E++        +    ++L + A   
Sbjct: 1235 GNVTYMLITDGDQKIPFSISPLDGTIRVSGEIDREMIASYRFRVLASDNNFDLKLSAM-- 1292

Query: 773  PLWNDVRVEILVTDVNDNAP 792
                 V VE++V D NDN P
Sbjct: 1293 -----VDVEVIVMDRNDNNP 1307



 Score = 52.4 bits (120), Expect = 2e-04
 Identities = 78/358 (21%), Positives = 148/358 (41%), Gaps = 35/358 (9%)

Query: 539  LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598
            LDRE +    L + A D    +L    +++I ++DVND  PVF++         + +  T
Sbjct: 967  LDREEIESLTLKMMATDRD--NLMSEVELKILILDVNDCAPVFERIAIFRKSRCEMIENT 1024

Query: 599  SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP--ASGVIRTNKALDRESVATHDLK 656
            S       D ++     I  E+ P+  + G   ++   + G +  N+  DRE +      
Sbjct: 1025 S-------DLELMYLDEIETEVLPEFLDAGLMEMNSRVSYGSVMVNRTADREHLTMR--- 1074

Query: 657  AVAIDGGTPPQSSTVIVHIKIEDIN-DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715
                           +   K+     ++  V +   L F + EN  +G  I ++ A+D D
Sbjct: 1075 -------------RKLYKQKVRQRGRNTRAVAKKSQLKFALPENVEVGKVIFKLTANDDD 1121

Query: 716  EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW 775
               N+ V Y + G  + NS    +    D+      V  +   P    +L I A      
Sbjct: 1122 FEKNSKVFYEVVGQTELNSGERVSYFRIDRNNGELRV-ANRLPPETDVKLNITAKDVGGL 1180

Query: 776  NDV-RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV--GPFGRVPAYDAD--VTDKLQYR 830
            +D+ +V+  V DVNDNAPV +     FN  +  +P+     G+V A D D  +   + Y 
Sbjct: 1181 SDMLQVQFRVYDVNDNAPVFEKQWYTFNVDEGSYPITGKKIGQVRANDEDTGMNGNVTYM 1240

Query: 831  ILSGNNANL-ILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887
            +++  +  +   ++   G++ +S +++  +       V  +D   ++K    + V +I
Sbjct: 1241 LITDGDQKIPFSISPLDGTIRVSGEIDREMIASYRFRVLASDNNFDLKLSAMVDVEVI 1298



 Score = 48.0 bits (109), Expect = 0.004
 Identities = 50/219 (22%), Positives = 103/219 (47%), Gaps = 25/219 (11%)

Query: 7   IHQQINVLDCNDHSPVFEMQQ-YEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELV 65
           +  +I +LD ND++P FE    YE      AS G+ V  ++A D D   N +++Y+I+ V
Sbjct: 450 VQVEITLLDTNDNTPEFEQGTLYEFKTHCNASIGSKVGQIRALDPDDLGNGKIQYSIKNV 509

Query: 66  TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125
             + + P                 F +D  +G +    +L   K+A +   V+A DQ   
Sbjct: 510 RPNLVIP-----------------FLLDPDTGDIRVSEALTYGKIAFF---VEARDQPQN 549

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185
            S+   + A + ++I+  +    +F    Y   V  D ++  +  + +I+ T  D+ ++ 
Sbjct: 550 PSESRFNVALVTIDIVCQSIEDIEFIGAPYEFWVGADAAIGSS--VGQIRTT-FDMVSDE 606

Query: 186 AIRYAIIGGNTQ-MQFSIDSLSGDVSLVKTLDYEQVRSY 223
            I + ++    + + F+I+  SG V+++++++    R Y
Sbjct: 607 EIFFDLLHSYPEGVPFAIEERSGIVTVIESMEKFDRRCY 645



 Score = 42.7 bits (96), Expect = 0.14
 Identities = 29/67 (43%), Positives = 35/67 (52%), Gaps = 6/67 (8%)

Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTI---GEIRAHDPD-EGPNAVVHYSIKG 728
           V I +ED ND+PP F        I+ENSPIGT I     I   D D  GPN+   Y +  
Sbjct: 838 VVIVVEDENDNPPTFNQPFFLGVIAENSPIGTEIVLNNPIIISDMDAAGPNS--EYELLL 895

Query: 729 GDDSNSF 735
             +SNSF
Sbjct: 896 SGESNSF 902



 Score = 41.9 bits (94), Expect = 0.25
 Identities = 22/54 (40%), Positives = 32/54 (59%), Gaps = 2/54 (3%)

Query: 11   INVLDCNDHSPVFEMQQYE--ASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62
            I V+D ND++PVF        + V + A+ G  V+ ++ATD D G N EV YT+
Sbjct: 1555 IKVVDVNDNAPVFRDNYGPIISVVPDTANYGYAVMKVEATDDDAGSNGEVRYTL 1608



 Score = 36.7 bits (81), Expect = 9.2
 Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 1/72 (1%)

Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR-SNTTQLLINIRDVNDNAPRFYTSLFQES 265
           G +  +K LD E+    R+ I A+        +   Q++I + D NDN P F    F   
Sbjct: 801 GKLMTIKGLDREKQDVIRVTIIAEYFYKQRTFAGIYQVVIVVEDENDNPPTFNQPFFLGV 860

Query: 266 VSENVPIGYSIV 277
           ++EN PIG  IV
Sbjct: 861 IAENSPIGTEIV 872


>UniRef50_A0NBP5 Cluster: ENSANGP00000031609; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000031609 - Anopheles gambiae
           str. PEST
          Length = 369

 Score =  143 bits (347), Expect = 5e-32
 Identities = 129/396 (32%), Positives = 204/396 (51%), Gaps = 37/396 (9%)

Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMV--QINITDANNYAPVFENAPYTAS-VFEDAPIG 485
           L+ +    +V+ V A D+ G S   +V  ++ + D N++ P FE   Y  + + EDA I 
Sbjct: 2   LEHEPADTFVMQVKAHDNDGTSAHNIVSYRLEVLDKNDHPPRFEEQYYEVNNIPEDADIN 61

Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545
           T+V+ V ATD D   + +I YS+   I N       + F I+  TG I+ NK LD E++ 
Sbjct: 62  TSVIKVKATDLDK--DPKIQYSI---IENNI----GKAFKIDEDTGLISVNKKLDYESIQ 112

Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN-IMEDALVGTSVSQVG 604
            Y L V A DG   S   TT++ I V+D ND+ P F++Q Y  N I EDA + TSV +V 
Sbjct: 113 EYDLVVQAHDGLFKS---TTNLFIRVLDKNDHPPRFEEQYYEVNNIPEDADINTSVIKVK 169

Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664
            TD D   + +I Y +   +  + ++ ID  +G+I  NK LD ES+  +DL   A DG  
Sbjct: 170 TTDLDK--DPKIKYSIIENNIGK-AYKIDEDTGLISVNKKLDYESIQEYDLVVQAHDGLF 226

Query: 665 PPQSSTVIVHIKIEDIND-SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723
               ST  V I+I+++ND +P +     +T  I EN+     I  + A+DPD     + +
Sbjct: 227 ---KSTTNVRIEIKNLNDIAPQILTLTNVT--IKENTIPSDCIANLWAYDPD-----IEN 276

Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY--ELVIR-AASPPLWNDVRV 780
           + +   D      ++ R  +   EL ++V+ D E  +K+Y   ++IR +   P+    ++
Sbjct: 277 FDV---DPDAPTEIKNRFQTVGDELYSLVEFDREQ-QKQYLVPILIRDSGHKPMSAVSKL 332

Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRV 816
            +++ D NDN   M    I+ NNY+  F     GRV
Sbjct: 333 LVVIGDKNDNEMQMGQSHILVNNYEGKFADTQIGRV 368



 Score =  134 bits (324), Expect = 3e-29
 Identities = 104/346 (30%), Positives = 165/346 (47%), Gaps = 45/346 (13%)

Query: 7   IHQQINVLDCNDHSPVFEMQQYEAS-VREGASSGTTVLTLKATDQDIGKNAEVEYTIELV 65
           +  ++ VLD NDH P FE Q YE + + E A   T+V+ +KATD D  K+ +++Y+I   
Sbjct: 28  VSYRLEVLDKNDHPPRFEEQYYEVNNIPEDADINTSVIKVKATDLD--KDPKIQYSI--- 82

Query: 66  TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125
                               +   F+ID  +G +     LD E +  Y ++V+A D    
Sbjct: 83  ----------------IENNIGKAFKIDEDTGLISVNKKLDYESIQEYDLVVQAHDGL-- 124

Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS-VDEDISVTDNPVIAKIKATDADVGAN 184
                 ST  + + ++D ND+ P+F E+ Y V+ + ED  +  N  + K+K TD D   +
Sbjct: 125 ----FKSTTNLFIRVLDKNDHPPRFEEQYYEVNNIPEDADI--NTSVIKVKTTDLD--KD 176

Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244
             I+Y+II  N    + ID  +G +S+ K LDYE ++ Y LV++A DG   S   TT + 
Sbjct: 177 PKIKYSIIENNIGKAYKIDEDTGLISVNKKLDYESIQEYDLVVQAHDGLFKS---TTNVR 233

Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304
           I I+++ND AP+  T L   ++ EN      I  + AYD D            D D    
Sbjct: 234 IEIKNLNDIAPQILT-LTNVTIKENTIPSDCIANLWAYDPD--------IENFDVDPDAP 284

Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350
            ++          +Y+  + DRE Q +Y + +   D G  P SA +
Sbjct: 285 TEIKNRFQTVGDELYSLVEFDREQQKQYLVPILIRDSGHKPMSAVS 330



 Score =  116 bits (280), Expect = 7e-24
 Identities = 95/355 (26%), Positives = 167/355 (47%), Gaps = 26/355 (7%)

Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTV-SVDEDI 163
           L+ E    + + VKA D     +  + S     + ++D ND+ P+F E+ Y V ++ ED 
Sbjct: 2   LEHEPADTFVMQVKAHDNDGTSAHNIVS---YRLEVLDKNDHPPRFEEQYYEVNNIPEDA 58

Query: 164 SVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY 223
            +  N  + K+KATD D   +  I+Y+II  N    F ID  +G +S+ K LDYE ++ Y
Sbjct: 59  DI--NTSVIKVKATDLD--KDPKIQYSIIENNIGKAFKIDEDTGLISVNKKLDYESIQEY 114

Query: 224 RLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ-ESVSENVPIGYSIVRVQAY 282
            LV++A DG   S   TT L I + D ND+ PRF    ++  ++ E+  I  S+++V+  
Sbjct: 115 DLVVQAHDGLFKS---TTNLFIRVLDKNDHPPRFEEQYYEVNNIPEDADINTSVIKVKTT 171

Query: 283 DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG 342
           D D+  + ++ Y++ +     N+     ID  +G +  + +LD E+  +Y L+V A DG 
Sbjct: 172 DLDK--DPKIKYSIIE----NNIGKAYKIDEDTGLISVNKKLDYESIQEYDLVVQAHDG- 224

Query: 343 DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYE 402
                 + T               +     V + E+  P   +  L A D D +N     
Sbjct: 225 ---LFKSTTNVRIEIKNLNDIAPQILTLTNVTIKENTIPSDCIANLWAYDPDIENFDVDP 281

Query: 403 ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQI 457
                 + RF         L+      D +Q+++Y++ +   DSG +  +A+ ++
Sbjct: 282 DAPTEIKNRFQTVGDELYSLV----EFDREQQKQYLVPILIRDSGHKPMSAVSKL 332



 Score =  109 bits (263), Expect = 8e-22
 Identities = 97/391 (24%), Positives = 168/391 (42%), Gaps = 26/391 (6%)

Query: 215 LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ-ESVSENVPIG 273
           L++E   ++ + ++A D    S  N     + + D ND+ PRF    ++  ++ E+  I 
Sbjct: 2   LEHEPADTFVMQVKAHDNDGTSAHNIVSYRLEVLDKNDHPPRFEEQYYEVNNIPEDADIN 61

Query: 274 YSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQ 333
            S+++V+A D D+  + ++ Y++ +     N+     ID  +G +  + +LD E+  +Y 
Sbjct: 62  TSVIKVKATDLDK--DPKIQYSIIEN----NIGKAFKIDEDTGLISVNKKLDYESIQEYD 115

Query: 334 LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE-LAEDEPPGTPVVTLTATD 392
           L+V A DG      +T                F    YEV  + ED    T V+ +  TD
Sbjct: 116 LVVQAHDG---LFKSTTNLFIRVLDKNDHPPRFEEQYYEVNNIPEDADINTSVIKVKTTD 172

Query: 393 ADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT 452
            D+D ++ Y I   N    + I    G  LI+V + LD++  + Y L V A D   +S T
Sbjct: 173 LDKDPKIKYSIIENNIGKAYKIDEDTG--LISVNKKLDYESIQEYDLVVQAHDGLFKS-T 229

Query: 453 AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512
             V+I I + N+ AP         ++ E+      +  + A D D+  N  +     +EI
Sbjct: 230 TNVRIEIKNLNDIAPQILTLT-NVTIKENTIPSDCIANLWAYDPDIE-NFDVDPDAPTEI 287

Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572
            N      D+ + +             DRE    YL+ +  RD G   +S  + + + + 
Sbjct: 288 KNRFQTVGDELYSLVE----------FDREQQKQYLVPILIRDSGHKPMSAVSKLLVVIG 337

Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603
           D NDNE    Q     N  E     T + +V
Sbjct: 338 DKNDNEMQMGQSHILVNNYEGKFADTQIGRV 368



 Score =  108 bits (260), Expect = 2e-21
 Identities = 86/288 (29%), Positives = 142/288 (49%), Gaps = 16/288 (5%)

Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA-NIMEDALV 596
           +L+ E    +++ V A D    S  +     + V+D ND+ P F++Q Y   NI EDA +
Sbjct: 1   ILEHEPADTFVMQVKAHDNDGTSAHNIVSYRLEVLDKNDHPPRFEEQYYEVNNIPEDADI 60

Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656
            TSV +V ATD D   + +I Y +   +  + +F ID  +G+I  NK LD ES+  +DL 
Sbjct: 61  NTSVIKVKATDLD--KDPKIQYSIIENNIGK-AFKIDEDTGLISVNKKLDYESIQEYDLV 117

Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF-YISENSPIGTTIGEIRAHDPD 715
             A DG      ST  + I++ D ND PP FE        I E++ I T++ +++  D D
Sbjct: 118 VQAHDG---LFKSTTNLFIRVLDKNDHPPRFEEQYYEVNNIPEDADINTSVIKVKTTDLD 174

Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW 775
           + P   + YSI   +   ++ ++     D   +     LDYES  ++Y+LV++A      
Sbjct: 175 KDPK--IKYSIIENNIGKAYKID----EDTGLISVNKKLDYES-IQEYDLVVQAHDGLFK 227

Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV 823
           +   V I + ++ND AP +     +    ++  P      + AYD D+
Sbjct: 228 STTNVRIEIKNLNDIAPQILTLTNV-TIKENTIPSDCIANLWAYDPDI 274



 Score = 68.5 bits (160), Expect = 2e-09
 Identities = 72/244 (29%), Positives = 108/244 (44%), Gaps = 35/244 (14%)

Query: 11  INVLDCNDHSPVFEMQQYEAS-VREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69
           I VLD NDH P FE Q YE + + E A   T+V+ +K TD D  K+ +++Y+I       
Sbjct: 133 IRVLDKNDHPPRFEEQYYEVNNIPEDADINTSVIKVKTTDLD--KDPKIKYSI------- 183

Query: 70  LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129
                           +   ++ID  +G +     LD E +  Y ++V+A D        
Sbjct: 184 ------------IENNIGKAYKIDEDTGLISVNKKLDYESIQEYDLVVQAHDGL------ 225

Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189
             ST  + + I + ND  PQ    T  V++ E+   +D   IA + A D D+        
Sbjct: 226 FKSTTNVRIEIKNLNDIAPQILTLT-NVTIKENTIPSD--CIANLWAYDPDIENFDVDPD 282

Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249
           A      + Q   D L    SLV+  D EQ + Y + I  +D G    S  ++LL+ I D
Sbjct: 283 APTEIKNRFQTVGDEL---YSLVE-FDREQQKQYLVPILIRDSGHKPMSAVSKLLVVIGD 338

Query: 250 VNDN 253
            NDN
Sbjct: 339 KNDN 342



 Score = 37.5 bits (83), Expect = 5.3
 Identities = 28/113 (24%), Positives = 52/113 (46%), Gaps = 3/113 (2%)

Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVTDKLQYRILSG 834
           N V   + V D ND+ P  ++     NN  +   +     +V A D D   K+QY I+  
Sbjct: 26  NIVSYRLEVLDKNDHPPRFEEQYYEVNNIPEDADINTSVIKVKATDLDKDPKIQYSIIEN 85

Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887
           N      ++E TG ++++ +L+    +   + V   DG+   K+   L +R++
Sbjct: 86  NIGKAFKIDEDTGLISVNKKLDYESIQEYDLVVQAHDGL--FKSTTNLFIRVL 136


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.317    0.134    0.404 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 3,126,570,439
Number of Sequences: 1657284
Number of extensions: 138148970
Number of successful extensions: 382967
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 923
Number of HSP's successfully gapped in prelim test: 1082
Number of HSP's that attempted gapping in prelim test: 323038
Number of HSP's gapped (non-prelim): 31612
length of query: 2796
length of database: 575,637,011
effective HSP length: 114
effective length of query: 2682
effective length of database: 386,706,635
effective search space: 1037147195070
effective search space used: 1037147195070
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 81 (36.7 bits)

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