BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000467-TA|BGIBMGA000467-PA|IPR002126|Cadherin, IPR006209|EGF-like, IPR012680|Laminin G, subdomain 2, IPR002049|EGF-like, laminin, IPR001879|Hormone receptor, extracellular, IPR000203|GPS, IPR000152|Aspartic acid and asparagine hydroxylation site, IPR013032|EGF-like region, IPR000005|Helix-turn-helix, AraC type, IPR000083|Fibronectin, type I, IPR006210|EGF, IPR001791|Laminin G, IPR001881|EGF-like calcium-binding, IPR000742|EGF-like, type 3 (2796 letters) Database: uniref50 1,657,284 sequences; 575,637,011 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value UniRef50_Q9V5N8 Cluster: Protocadherin-like wing polarity protei... 2285 0.0 UniRef50_Q7PPU8 Cluster: ENSANGP00000001238; n=2; Culicidae|Rep:... 1495 0.0 UniRef50_UPI0000DB794E Cluster: PREDICTED: similar to Protocadhe... 1433 0.0 UniRef50_Q4S7X0 Cluster: Chromosome 9 SCAF14710, whole genome sh... 1381 0.0 UniRef50_Q9NYQ6 Cluster: Cadherin EGF LAG seven-pass G-type rece... 922 0.0 UniRef50_Q9NYQ7 Cluster: Cadherin EGF LAG seven-pass G-type rece... 903 0.0 UniRef50_Q9HCU4 Cluster: Cadherin EGF LAG seven-pass G-type rece... 901 0.0 UniRef50_Q4RXP0 Cluster: Chromosome 11 SCAF14979, whole genome s... 810 0.0 UniRef50_A7RKF4 Cluster: Predicted protein; n=2; Nematostella ve... 617 e-174 UniRef50_Q16QV0 Cluster: Cadherin; n=10; Eukaryota|Rep: Cadherin... 491 e-136 UniRef50_Q4SDW5 Cluster: Chromosome undetermined SCAF14629, whol... 479 e-133 UniRef50_UPI0000E473B7 Cluster: PREDICTED: similar to KIAA0279 p... 475 e-132 UniRef50_Q8MY78 Cluster: Ap-cadherin; n=1; Patiria pectinifera|R... 472 e-131 UniRef50_A7RQM0 Cluster: Predicted protein; n=2; Nematostella ve... 471 e-130 UniRef50_Q6W4W6 Cluster: CHz-cadherin; n=19; Euteleostomi|Rep: C... 468 e-129 UniRef50_UPI00015B6261 Cluster: PREDICTED: similar to CG7749-PA;... 462 e-128 UniRef50_Q14517 Cluster: Cadherin-related tumor suppressor homol... 459 e-127 UniRef50_Q9VW71 Cluster: Putative fat-like cadherin-related tumo... 443 e-122 UniRef50_A6NIM4 Cluster: Uncharacterized protein FAT3; n=43; Eut... 433 e-119 UniRef50_A7S3G3 Cluster: Predicted protein; n=2; Nematostella ve... 429 e-118 UniRef50_UPI00006A0F37 Cluster: dachsous 2 isoform 1; n=1; Xenop... 420 e-115 UniRef50_O15943 Cluster: Neural-cadherin precursor; n=42; Arthro... 409 e-112 UniRef50_UPI00006A0F32 Cluster: dachsous 2 isoform 1; n=1; Xenop... 407 e-111 UniRef50_UPI00004D1B71 Cluster: SH3 adapter protein SPIN90 (NCK-... 407 e-111 UniRef50_Q4SRY5 Cluster: Chromosome 18 SCAF14485, whole genome s... 407 e-111 UniRef50_UPI0000E46DFB Cluster: PREDICTED: hypothetical protein;... 398 e-108 UniRef50_Q6V0I7 Cluster: FAT tumor suppressor homolog 4; n=35; E... 397 e-108 UniRef50_UPI0000E48843 Cluster: PREDICTED: similar to Fat4; n=2;... 396 e-108 UniRef50_Q4SFW8 Cluster: Chromosome 7 SCAF14601, whole genome sh... 394 e-107 UniRef50_A7T100 Cluster: Predicted protein; n=1; Nematostella ve... 385 e-104 UniRef50_A7S751 Cluster: Predicted protein; n=1; Nematostella ve... 385 e-104 UniRef50_UPI00015A700B Cluster: UPI00015A700B related cluster; n... 378 e-103 UniRef50_UPI00006A0F38 Cluster: dachsous 2 isoform 1; n=1; Xenop... 378 e-103 UniRef50_UPI0000F1F871 Cluster: PREDICTED: similar to FAT tumor ... 376 e-102 UniRef50_A7SN97 Cluster: Predicted protein; n=1; Nematostella ve... 376 e-102 UniRef50_Q7Q3K5 Cluster: ENSANGP00000007226; n=1; Anopheles gamb... 374 e-101 UniRef50_Q4S3T8 Cluster: Chromosome 20 SCAF14744, whole genome s... 373 e-101 UniRef50_A7SLK9 Cluster: Predicted protein; n=1; Nematostella ve... 373 e-101 UniRef50_UPI00006A0F33 Cluster: dachsous 2 isoform 1; n=1; Xenop... 372 e-100 UniRef50_Q17NI8 Cluster: Cadherin; n=3; cellular organisms|Rep: ... 372 e-100 UniRef50_UPI00015A7221 Cluster: UPI00015A7221 related cluster; n... 370 e-100 UniRef50_UPI0000F200F1 Cluster: PREDICTED: similar to Fat4; n=3;... 369 e-100 UniRef50_A7SLL0 Cluster: Predicted protein; n=2; Nematostella ve... 367 2e-99 UniRef50_Q24292 Cluster: Protein dachsous precursor; n=3; Drosop... 359 5e-97 UniRef50_A7RQ19 Cluster: Predicted protein; n=5; Nematostella ve... 356 6e-96 UniRef50_UPI000065D51F Cluster: Homolog of Homo sapiens "Fat-lik... 355 1e-95 UniRef50_Q9H251 Cluster: Cadherin-23 precursor; n=51; Euteleosto... 355 1e-95 UniRef50_Q6V1P9 Cluster: Dachsous-2; n=9; Eutheria|Rep: Dachsous... 352 7e-95 UniRef50_UPI0000F3174E Cluster: dachsous 2 isoform 1; n=9; Theri... 351 1e-94 UniRef50_UPI000069E6F8 Cluster: dachsous 2 isoform 1; n=1; Xenop... 349 5e-94 UniRef50_A7SAP5 Cluster: Predicted protein; n=1; Nematostella ve... 347 3e-93 UniRef50_UPI0000E7FC61 Cluster: PREDICTED: similar to dachsous 1... 345 1e-92 UniRef50_Q4S3T6 Cluster: Chromosome 20 SCAF14744, whole genome s... 340 4e-91 UniRef50_P33450 Cluster: Cadherin-related tumor suppressor precu... 340 4e-91 UniRef50_UPI0000E49AEF Cluster: PREDICTED: similar to Fat4; n=5;... 339 5e-91 UniRef50_Q9NYQ8 Cluster: Protocadherin Fat 2 precursor; n=19; Am... 339 7e-91 UniRef50_UPI0000F1D37C Cluster: PREDICTED: hypothetical protein;... 336 4e-90 UniRef50_Q4SRZ9 Cluster: Chromosome 18 SCAF14485, whole genome s... 334 3e-89 UniRef50_A7S5N5 Cluster: Predicted protein; n=1; Nematostella ve... 333 5e-89 UniRef50_UPI00006610B3 Cluster: Homolog of Brachydanio rerio "Ca... 327 3e-87 UniRef50_UPI00006A2595 Cluster: Protocadherin-16 precursor (Dach... 322 7e-86 UniRef50_UPI0000660D80 Cluster: Homolog of Brachydanio rerio "Pr... 321 2e-85 UniRef50_A7RI52 Cluster: Predicted protein; n=1; Nematostella ve... 318 1e-84 UniRef50_Q17LY6 Cluster: Cadherin; n=6; Culicidae|Rep: Cadherin ... 314 3e-83 UniRef50_Q96JQ0 Cluster: Protocadherin-16 precursor; n=12; Amnio... 314 3e-83 UniRef50_Q4SVG4 Cluster: Chromosome 1 SCAF13759, whole genome sh... 313 4e-83 UniRef50_UPI000155CE87 Cluster: PREDICTED: similar to FAT tumor ... 311 2e-82 UniRef50_Q60YX0 Cluster: Putative uncharacterized protein CBG180... 310 3e-82 UniRef50_A7S5P0 Cluster: Predicted protein; n=3; Nematostella ve... 309 6e-82 UniRef50_Q7YWB9 Cluster: Cadherin-like protein cad2; n=1; Aplysi... 303 3e-80 UniRef50_Q7PTV6 Cluster: ENSANGP00000002131; n=1; Anopheles gamb... 303 3e-80 UniRef50_Q4SYV0 Cluster: Chromosome undetermined SCAF11948, whol... 296 6e-78 UniRef50_UPI0000E81ED5 Cluster: PREDICTED: similar to protocadhe... 295 9e-78 UniRef50_UPI00015B6339 Cluster: PREDICTED: similar to ENSANGP000... 294 2e-77 UniRef50_Q08174 Cluster: Protocadherin-1 precursor; n=52; Eutele... 294 3e-77 UniRef50_A7S9Y3 Cluster: Predicted protein; n=2; Nematostella ve... 293 3e-77 UniRef50_UPI0000E7FFCA Cluster: PREDICTED: similar to FAT tumor ... 293 6e-77 UniRef50_A7RQ21 Cluster: Predicted protein; n=2; Nematostella ve... 288 2e-75 UniRef50_Q4SVN1 Cluster: Chromosome 1 SCAF13750, whole genome sh... 287 4e-75 UniRef50_Q19319 Cluster: Cadherin-4 precursor; n=1; Caenorhabdit... 285 1e-74 UniRef50_UPI000065CB4F Cluster: Protocadherin-9 precursor.; n=2;... 285 2e-74 UniRef50_Q4SVM9 Cluster: Chromosome 1 SCAF13750, whole genome sh... 281 3e-73 UniRef50_Q9BZA7 Cluster: Protocadherin-11 X-linked precursor; n=... 281 3e-73 UniRef50_Q4S3N9 Cluster: Chromosome 17 SCAF14747, whole genome s... 280 3e-73 UniRef50_Q4RPF4 Cluster: Chromosome 1 SCAF15008, whole genome sh... 278 2e-72 UniRef50_Q4T0W6 Cluster: Chromosome 1 SCAF10821, whole genome sh... 277 2e-72 UniRef50_Q4SFY8 Cluster: Chromosome 7 SCAF14601, whole genome sh... 277 2e-72 UniRef50_A7SN99 Cluster: Predicted protein; n=1; Nematostella ve... 276 7e-72 UniRef50_UPI0000660C02 Cluster: Homolog of Brachydanio rerio "Pr... 273 4e-71 UniRef50_UPI0000E4A946 Cluster: PREDICTED: similar to cadherin 2... 272 7e-71 UniRef50_A7SN98 Cluster: Predicted protein; n=2; Nematostella ve... 272 7e-71 UniRef50_UPI0000DB71FC Cluster: PREDICTED: similar to Cad87A CG6... 272 9e-71 UniRef50_Q96QU1 Cluster: Protocadherin-15 precursor; n=69; Eutel... 272 9e-71 UniRef50_UPI0000F2053F Cluster: PREDICTED: similar to FAT tumor ... 268 1e-69 UniRef50_UPI00006A1F6A Cluster: UPI00006A1F6A related cluster; n... 260 3e-67 UniRef50_A6VVW9 Cluster: Autotransporter-associated beta strand ... 260 4e-67 UniRef50_UPI0000D5573F Cluster: PREDICTED: similar to CG3389-PA;... 260 5e-67 UniRef50_Q967F4 Cluster: Cadherin-related hmr-1 precursor; n=3; ... 258 1e-66 UniRef50_Q4S488 Cluster: Chromosome undetermined SCAF14743, whol... 258 2e-66 UniRef50_Q5F4W0 Cluster: Putative uncharacterized protein; n=3; ... 256 8e-66 UniRef50_UPI0000DB7905 Cluster: PREDICTED: similar to Cad99C CG3... 255 1e-65 UniRef50_Q60I71 Cluster: Cadherin-related neuronal receptor vari... 255 1e-65 UniRef50_Q7PUW9 Cluster: ENSANGP00000018135; n=2; Anopheles gamb... 254 3e-65 UniRef50_Q9VGG5 Cluster: Cadherin 87A precursor; n=2; Diptera|Re... 254 3e-65 UniRef50_Q9Y5F6 Cluster: Protocadherin gamma C5 precursor; n=49;... 252 8e-65 UniRef50_Q5ICW6 Cluster: Protocadherin 15a; n=8; Clupeocephala|R... 248 1e-63 UniRef50_Q9VAF5 Cluster: CG31009-PA; n=9; Diptera|Rep: CG31009-P... 246 9e-63 UniRef50_O60245 Cluster: Protocadherin-7 precursor; n=52; Eutele... 245 1e-62 UniRef50_Q174A5 Cluster: Cadherin; n=1; Aedes aegypti|Rep: Cadhe... 245 2e-62 UniRef50_UPI0000E81FAF Cluster: PREDICTED: similar to Protocadhe... 244 2e-62 UniRef50_Q7QJ26 Cluster: ENSANGP00000009575; n=6; Culicidae|Rep:... 244 3e-62 UniRef50_Q8MY75 Cluster: Pf1-cadherin; n=1; Ptychodera flava|Rep... 244 4e-62 UniRef50_UPI00015A41E3 Cluster: UPI00015A41E3 related cluster; n... 243 5e-62 UniRef50_A7SHT2 Cluster: Predicted protein; n=1; Nematostella ve... 242 8e-62 UniRef50_Q8N6Y1 Cluster: Protocadherin-20 precursor; n=28; Eutel... 242 8e-62 UniRef50_UPI000155BF0A Cluster: PREDICTED: similar to protocadhe... 242 1e-61 UniRef50_UPI0000583D73 Cluster: PREDICTED: hypothetical protein;... 242 1e-61 UniRef50_Q8TAB3 Cluster: Protocadherin-19 precursor; n=31; Eutel... 241 3e-61 UniRef50_Q5CCS6 Cluster: Af1-cadherin; n=1; Artemia franciscana|... 239 6e-61 UniRef50_UPI00006A1011 Cluster: FAT tumor suppressor homolog 3; ... 239 1e-60 UniRef50_Q4RKB4 Cluster: Chromosome 18 SCAF15030, whole genome s... 239 1e-60 UniRef50_UPI00006A0F39 Cluster: Protocadherin alpha 13 precursor... 238 1e-60 UniRef50_A7SSF2 Cluster: Predicted protein; n=2; Nematostella ve... 237 2e-60 UniRef50_Q9VJB6 Cluster: Putative neural-cadherin 2 precursor; n... 237 2e-60 UniRef50_A4KCK1 Cluster: Protocadherin 2A37; n=12; Clupeocephala... 237 4e-60 UniRef50_Q7PT49 Cluster: ENSANGP00000019477; n=1; Anopheles gamb... 235 2e-59 UniRef50_Q17NI9 Cluster: Protocadherin; n=3; Endopterygota|Rep: ... 234 2e-59 UniRef50_Q4SJS0 Cluster: Chromosome 1 SCAF14573, whole genome sh... 234 3e-59 UniRef50_Q60H51 Cluster: Protocadherin2-gamma-v5-sCP1; n=11; Clu... 233 5e-59 UniRef50_Q9Y5H6 Cluster: Protocadherin alpha 8 precursor; n=204;... 231 2e-58 UniRef50_UPI0000E80F11 Cluster: PREDICTED: similar to protocadhe... 231 2e-58 UniRef50_UPI0000E80EB1 Cluster: PREDICTED: similar to cadherin-r... 230 4e-58 UniRef50_Q60H55 Cluster: Protocadherin2-gamma-v12-sCP1; n=8; Dan... 230 5e-58 UniRef50_UPI0000DB7673 Cluster: PREDICTED: similar to Cad74A CG6... 229 8e-58 UniRef50_Q4SVM8 Cluster: Chromosome 1 SCAF13750, whole genome sh... 229 8e-58 UniRef50_UPI00004F6742 Cluster: protocadherin 1 gamma 32; n=3; D... 229 1e-57 UniRef50_Q8IGX4 Cluster: RE10062p; n=6; Diptera|Rep: RE10062p - ... 229 1e-57 UniRef50_Q9Y5I4 Cluster: Protocadherin alpha C2 precursor; n=23;... 228 1e-57 UniRef50_Q9Y5H7 Cluster: Protocadherin alpha 5 precursor; n=15; ... 228 1e-57 UniRef50_P34616 Cluster: Cadherin-3 precursor; n=13; root|Rep: C... 228 2e-57 UniRef50_Q0V9M2 Cluster: Putative uncharacterized protein MGC146... 227 3e-57 UniRef50_UPI0000E821D2 Cluster: PREDICTED: similar to protocadhe... 227 3e-57 UniRef50_A4KCM6 Cluster: Protocadherin 2G25; n=4; Takifugu rubri... 227 3e-57 UniRef50_UPI0000F1FBA8 Cluster: PREDICTED: hypothetical protein;... 226 6e-57 UniRef50_A1L1W7 Cluster: LOC555688 protein; n=6; Euteleostomi|Re... 226 8e-57 UniRef50_Q60I64 Cluster: Cadherin-related neuronal receptor cons... 225 1e-56 UniRef50_Q9Y5F3 Cluster: Protocadherin beta 1 precursor; n=260; ... 225 2e-56 UniRef50_Q60H65 Cluster: Protocadherin1-alpha-av15-vCP; n=75; Eu... 224 2e-56 UniRef50_Q4SNX9 Cluster: Chromosome 15 SCAF14542, whole genome s... 221 2e-55 UniRef50_Q3V7B0 Cluster: Protocadherin alpha; n=22; Tetrapoda|Re... 221 2e-55 UniRef50_UPI0000F2DF7E Cluster: PREDICTED: similar to protocadhe... 220 4e-55 UniRef50_UPI000069E759 Cluster: UPI000069E759 related cluster; n... 220 4e-55 UniRef50_Q75QY0 Cluster: KIAA0811 protein; n=4; Eukaryota|Rep: K... 219 7e-55 UniRef50_Q86N71 Cluster: Cadherin-related protein; n=1; Aplysia ... 219 9e-55 UniRef50_O14917 Cluster: Protocadherin-17 precursor; n=23; Eutel... 219 9e-55 UniRef50_Q9HCL0 Cluster: Protocadherin-18 precursor; n=33; Eutel... 219 1e-54 UniRef50_Q60H59 Cluster: Protocadherin2-gamma-c6-sCP1; n=37; Clu... 217 3e-54 UniRef50_Q32PS9 Cluster: Pcdh1g18 protein; n=35; Clupeocephala|R... 217 4e-54 UniRef50_UPI00006614A3 Cluster: Homolog of Brachydanio rerio "Pr... 216 8e-54 UniRef50_Q24298 Cluster: DE-cadherin precursor; n=5; Neoptera|Re... 216 8e-54 UniRef50_UPI000065EB3B Cluster: Homolog of Brachydanio rerio "Pa... 215 1e-53 UniRef50_Q95YK1 Cluster: Protocadherin; n=1; Ciona savignyi|Rep:... 215 2e-53 UniRef50_Q9Y5H3 Cluster: Protocadherin gamma A10 precursor; n=11... 215 2e-53 UniRef50_UPI00004F6724 Cluster: protocadherin 1 gamma 1; n=3; Da... 214 3e-53 UniRef50_P73089 Cluster: Fat protein; n=1; Synechocystis sp. PCC... 214 3e-53 UniRef50_UPI0000E80EB2 Cluster: PREDICTED: hypothetical protein;... 213 4e-53 UniRef50_Q9VFH5 Cluster: CG3389-PA; n=2; Sophophora|Rep: CG3389-... 213 4e-53 UniRef50_Q9H158 Cluster: Protocadherin alpha C1 precursor; n=12;... 213 8e-53 UniRef50_UPI0000EB26D2 Cluster: UPI0000EB26D2 related cluster; n... 212 1e-52 UniRef50_Q5CCS8 Cluster: Fc1-cadherin; n=2; Hexapoda|Rep: Fc1-ca... 212 1e-52 UniRef50_UPI0000F1EDA6 Cluster: PREDICTED: hypothetical protein;... 211 2e-52 UniRef50_UPI0000E20B47 Cluster: PREDICTED: similar to Protocadhe... 210 3e-52 UniRef50_A7SSF1 Cluster: Predicted protein; n=1; Nematostella ve... 210 3e-52 UniRef50_Q9BYE9 Cluster: Protocadherin LKC precursor; n=17; Ther... 210 3e-52 UniRef50_Q47W44 Cluster: Cadherin domain protein; n=1; Colwellia... 210 4e-52 UniRef50_Q4S0C3 Cluster: Chromosome 2 SCAF14781, whole genome sh... 209 1e-51 UniRef50_UPI000069E7C3 Cluster: Protocadherin beta 11 precursor ... 206 5e-51 UniRef50_Q4S489 Cluster: Chromosome 1 SCAF14742, whole genome sh... 206 9e-51 UniRef50_Q9Y5H0 Cluster: Protocadherin gamma A3 precursor; n=173... 204 2e-50 UniRef50_UPI00006A0F40 Cluster: Protocadherin gamma C3 precursor... 204 3e-50 UniRef50_O93509 Cluster: Paraxial protocadherin; n=11; Xenopus|R... 204 4e-50 UniRef50_Q6EI13 Cluster: GammaA-like protocadherin precursor; n=... 203 5e-50 UniRef50_UPI0000E80EAB Cluster: PREDICTED: similar to Protocadhe... 203 6e-50 UniRef50_UPI00015B46FC Cluster: PREDICTED: similar to CG14900-PA... 202 8e-50 UniRef50_UPI0000E48BDB Cluster: PREDICTED: similar to FAT tumor ... 202 1e-49 UniRef50_Q9P2E7 Cluster: Protocadherin-10 precursor; n=34; Eutel... 202 1e-49 UniRef50_Q9HBT6 Cluster: Cadherin-20 precursor; n=261; Euteleost... 201 3e-49 UniRef50_Q6R0I8 Cluster: Cadherin-related neuronal receptor 3; n... 200 6e-49 UniRef50_O93508 Cluster: Paraxial protocadherin; n=6; Danio reri... 200 6e-49 UniRef50_UPI0000660F9A Cluster: Homolog of Brachydanio rerio "Ca... 199 8e-49 UniRef50_UPI0000DB7642 Cluster: PREDICTED: similar to Cad89D CG1... 198 2e-48 UniRef50_UPI000069FDB0 Cluster: Protocadherin LKC precursor (PC-... 198 2e-48 UniRef50_UPI0000F2B47D Cluster: PREDICTED: similar to matrix met... 196 5e-48 UniRef50_Q9UJ99 Cluster: Cadherin-22 precursor; n=19; Euteleosto... 196 1e-47 UniRef50_Q66S83 Cluster: Protocadherin 10-like protein; n=1; Oik... 195 2e-47 UniRef50_UPI000069ECF7 Cluster: UPI000069ECF7 related cluster; n... 194 3e-47 UniRef50_UPI0000ECABB6 Cluster: Protocadherin-12 precursor (Vasc... 194 4e-47 UniRef50_Q4T6J0 Cluster: Chromosome undetermined SCAF8736, whole... 192 9e-47 UniRef50_Q4RRF3 Cluster: Chromosome 16 SCAF15002, whole genome s... 191 3e-46 UniRef50_Q9NPG4 Cluster: Protocadherin-12 precursor; n=16; Theri... 190 5e-46 UniRef50_Q6R0H9 Cluster: Cadherin-related neuronal receptor c01;... 188 2e-45 UniRef50_Q4SM61 Cluster: Chromosome 13 SCAF14555, whole genome s... 188 2e-45 UniRef50_UPI000069E6F7 Cluster: UPI000069E6F7 related cluster; n... 188 3e-45 UniRef50_A7S9Y2 Cluster: Predicted protein; n=1; Nematostella ve... 187 3e-45 UniRef50_Q96JP9 Cluster: Protocadherin-21; n=30; Euteleostomi|Re... 187 4e-45 UniRef50_UPI0000660953 Cluster: Protocadherin-12 precursor (Vasc... 186 6e-45 UniRef50_UPI000054713A Cluster: PREDICTED: hypothetical protein;... 185 1e-44 UniRef50_Q7YZI2 Cluster: PRCDH1; n=1; Proterospongia sp. ATCC 50... 185 1e-44 UniRef50_UPI000065EA2C Cluster: Homolog of Homo sapiens "Protoca... 185 2e-44 UniRef50_Q9UN73-2 Cluster: Isoform 2 of Q9UN73 ; n=6; Mammalia|R... 184 4e-44 UniRef50_UPI0000E486F2 Cluster: PREDICTED: hypothetical protein;... 182 1e-43 UniRef50_Q4S490 Cluster: Chromosome 1 SCAF14742, whole genome sh... 182 2e-43 UniRef50_UPI00006A195F Cluster: Cadherin-16 precursor (Kidney-sp... 181 2e-43 UniRef50_Q4S1I3 Cluster: Chromosome 6 SCAF14768, whole genome sh... 180 5e-43 UniRef50_P55288 Cluster: Cadherin-11 precursor; n=28; Tetrapoda|... 179 9e-43 UniRef50_UPI0000F20039 Cluster: PREDICTED: hypothetical protein;... 177 4e-42 UniRef50_UPI0000E20B3B Cluster: PREDICTED: similar to Protocadhe... 172 1e-40 UniRef50_Q6V1P8 Cluster: Protocadherin protein; n=6; Catarrhini|... 172 1e-40 UniRef50_Q9H159 Cluster: Cadherin-19 precursor; n=15; Tetrapoda|... 171 2e-40 UniRef50_UPI0000D57279 Cluster: PREDICTED: similar to CG14900-PA... 170 5e-40 UniRef50_Q7UY44 Cluster: Fat protein-possibly involved in cell-c... 169 7e-40 UniRef50_Q4RIZ0 Cluster: Chromosome undetermined SCAF15040, whol... 167 3e-39 UniRef50_Q95YK9 Cluster: Type II cadherin; n=1; Ciona savignyi|R... 167 3e-39 UniRef50_Q5NUI3 Cluster: Cadherin19; n=12; Mammalia|Rep: Cadheri... 167 4e-39 UniRef50_A4GJB0 Cluster: Hypothetical cadherin domain containing... 166 9e-39 UniRef50_UPI000065CB52 Cluster: Homolog of Homo sapiens "Protoca... 164 3e-38 UniRef50_Q4RZD6 Cluster: Chromosome undetermined SCAF14942, whol... 163 5e-38 UniRef50_P33151 Cluster: Cadherin-5 precursor; n=34; Tetrapoda|R... 163 6e-38 UniRef50_UPI0000F1E792 Cluster: PREDICTED: hypothetical protein;... 163 8e-38 UniRef50_Q0YH47 Cluster: Cadherin; n=1; Geobacter sp. FRC-32|Rep... 161 2e-37 UniRef50_Q12864 Cluster: Cadherin-17 precursor; n=25; Tetrapoda|... 161 2e-37 UniRef50_P55283 Cluster: Cadherin-4 precursor; n=74; cellular or... 160 4e-37 UniRef50_Q9VEU1 Cluster: Cadherin 89D precursor; n=3; Sophophora... 157 4e-36 UniRef50_UPI000065EA0C Cluster: Cadherin-20 precursor.; n=1; Tak... 156 9e-36 UniRef50_UPI0000E81ECF Cluster: PREDICTED: similar to protocadhe... 155 2e-35 UniRef50_P12830 Cluster: Epithelial cadherin precursor (E-cadher... 154 4e-35 UniRef50_Q96LQ7 Cluster: CDNA FLJ25193 fis, clone JTH00761; n=13... 153 5e-35 UniRef50_P55290 Cluster: Cadherin-13 precursor; n=40; Euteleosto... 153 5e-35 UniRef50_Q4SS36 Cluster: Chromosome 11 SCAF14479, whole genome s... 153 7e-35 UniRef50_A7RRZ9 Cluster: Predicted protein; n=1; Nematostella ve... 151 2e-34 UniRef50_UPI0000660AA1 Cluster: Cadherin-7 precursor.; n=1; Taki... 151 4e-34 UniRef50_A6E164 Cluster: Large exoprotein; n=2; cellular organis... 149 8e-34 UniRef50_A7T102 Cluster: Predicted protein; n=1; Nematostella ve... 149 1e-33 UniRef50_Q6R8F2 Cluster: Epithelial cadherin precursor (E-cadher... 149 1e-33 UniRef50_UPI0000E473B6 Cluster: PREDICTED: similar to cadherin; ... 149 1e-33 UniRef50_Q4SF84 Cluster: Chromosome undetermined SCAF14607, whol... 149 1e-33 UniRef50_Q7SZW3 Cluster: Novel protein similar to zebrafish epit... 148 2e-33 UniRef50_Q90Z37 Cluster: E-cadherin; n=19; Danio rerio|Rep: E-ca... 145 1e-32 UniRef50_Q7PQL1 Cluster: ENSANGP00000011254; n=2; Culicidae|Rep:... 144 2e-32 UniRef50_A0NBP5 Cluster: ENSANGP00000031609; n=1; Anopheles gamb... 143 5e-32 UniRef50_Q1LX34 Cluster: Novel cadherin domain containing protei... 143 7e-32 UniRef50_O75309 Cluster: Cadherin-16 precursor; n=21; Theria|Rep... 142 1e-31 UniRef50_Q0E9Q8 Cluster: Protocadherin-17; n=6; Clupeocephala|Re... 141 2e-31 UniRef50_Q68SP4 Cluster: Cadherin 5; n=3; Danio rerio|Rep: Cadhe... 141 3e-31 UniRef50_UPI0000F1F8F4 Cluster: PREDICTED: hypothetical protein;... 140 5e-31 UniRef50_Q4S7A3 Cluster: Chromosome 1 SCAF14716, whole genome sh... 140 7e-31 UniRef50_Q676D4 Cluster: Cadherin; n=1; Oikopleura dioica|Rep: C... 140 7e-31 UniRef50_Q088L7 Cluster: Putative outer membrane adhesin like pr... 139 1e-30 UniRef50_Q1KKR4 Cluster: Cadherin 5; n=5; Tetraodontidae|Rep: Ca... 138 2e-30 UniRef50_Q86UP0 Cluster: Cadherin-24 precursor; n=17; Euteleosto... 138 2e-30 UniRef50_A3VZY4 Cluster: VCBS; n=6; Roseovarius|Rep: VCBS - Rose... 136 6e-30 UniRef50_UPI0000E49DF5 Cluster: PREDICTED: similar to protocadhe... 135 2e-29 UniRef50_A7T9P1 Cluster: Predicted protein; n=1; Nematostella ve... 134 3e-29 UniRef50_Q6T1F3 Cluster: M-cadherin; n=6; Danio rerio|Rep: M-cad... 134 4e-29 UniRef50_UPI0000DB741F Cluster: PREDICTED: similar to Cad96Cb CG... 133 6e-29 UniRef50_Q5DYB4 Cluster: Iron-regulated protein FrpC; n=1; Vibri... 133 6e-29 UniRef50_UPI00015A57B8 Cluster: UPI00015A57B8 related cluster; n... 132 2e-28 UniRef50_Q5W7K5 Cluster: Protocadherin-gamma; n=27; Clupeocephal... 132 2e-28 UniRef50_Q4S1I4 Cluster: Chromosome 6 SCAF14768, whole genome sh... 132 2e-28 UniRef50_A6QP71 Cluster: MGC155243 protein; n=2; Bos taurus|Rep:... 132 2e-28 UniRef50_UPI0000ECAEAF Cluster: Epithelial-cadherin precursor (E... 130 7e-28 UniRef50_Q172R3 Cluster: Cadherin, putative; n=1; Aedes aegypti|... 130 7e-28 UniRef50_Q32P55 Cluster: CDH23 protein; n=1; Homo sapiens|Rep: C... 130 7e-28 UniRef50_UPI000155655F Cluster: PREDICTED: similar to hCG1685761... 129 9e-28 UniRef50_UPI0000F1D9C2 Cluster: PREDICTED: hypothetical protein;... 129 1e-27 UniRef50_Q6P3M3 Cluster: Cadherin 17, LI cadherin; n=4; Danio re... 129 1e-27 UniRef50_Q17281 Cluster: Cadherin homolog; n=1; Botryllus schlos... 129 1e-27 UniRef50_UPI00015A74B2 Cluster: UPI00015A74B2 related cluster; n... 128 2e-27 UniRef50_UPI000155C764 Cluster: PREDICTED: similar to protocadhe... 128 3e-27 UniRef50_Q4SVQ0 Cluster: Chromosome undetermined SCAF13747, whol... 128 3e-27 UniRef50_Q4RE65 Cluster: Chromosome 2 SCAF15135, whole genome sh... 128 3e-27 UniRef50_Q8MY76 Cluster: Se-cadherin; n=1; Sexostrea echinata|Re... 128 3e-27 UniRef50_Q5TAN1 Cluster: Protocadherin 8; n=14; Tetrapoda|Rep: P... 128 3e-27 UniRef50_O95206 Cluster: Protocadherin-8 precursor; n=16; Tetrap... 128 3e-27 UniRef50_Q08BK3 Cluster: Dsc2l protein; n=5; Danio rerio|Rep: Ds... 127 4e-27 UniRef50_Q7PT75 Cluster: ENSANGP00000005839; n=2; Anopheles gamb... 126 9e-27 UniRef50_P55291 Cluster: Cadherin-15 precursor; n=11; Tetrapoda|... 126 9e-27 UniRef50_UPI0000E80331 Cluster: PREDICTED: similar to cadherin p... 126 1e-26 UniRef50_Q4SKV9 Cluster: Chromosome undetermined SCAF14565, whol... 126 1e-26 UniRef50_UPI0000D9A8A3 Cluster: PREDICTED: similar to fat tumor ... 125 2e-26 UniRef50_Q9NL47 Cluster: Cadherin; n=1; Ciona intestinalis|Rep: ... 125 2e-26 UniRef50_Q4S7A7 Cluster: Chromosome 1 SCAF14716, whole genome sh... 124 3e-26 UniRef50_A7RYP6 Cluster: Predicted protein; n=1; Nematostella ve... 123 6e-26 UniRef50_UPI0000ECD04C Cluster: CDNA FLJ44366 fis, clone TRACH30... 123 8e-26 UniRef50_Q7YWB8 Cluster: Cadherin-like protein cad3; n=1; Aplysi... 123 8e-26 UniRef50_Q1YNS7 Cluster: Cadherin domain protein; n=3; gamma pro... 121 3e-25 UniRef50_UPI00015A73E8 Cluster: UPI00015A73E8 related cluster; n... 120 4e-25 UniRef50_UPI00015B58A5 Cluster: PREDICTED: similar to GA18227-PA... 120 6e-25 UniRef50_Q4SGA8 Cluster: Chromosome 17 SCAF14597, whole genome s... 120 6e-25 UniRef50_Q0ALR4 Cluster: Serralysin precursor; n=1; Maricaulis m... 120 8e-25 UniRef50_Q96AU6 Cluster: FAT3 protein; n=13; Eukaryota|Rep: FAT3... 120 8e-25 UniRef50_UPI000065D984 Cluster: Homolog of Brachydanio rerio "E-... 119 1e-24 UniRef50_UPI000155D19D Cluster: PREDICTED: similar to cadherin-l... 119 1e-24 UniRef50_UPI0000660666 Cluster: Homolog of Brachydanio rerio "E-... 118 2e-24 UniRef50_Q4SM63 Cluster: Chromosome 13 SCAF14555, whole genome s... 118 2e-24 UniRef50_Q86T00 Cluster: Full-length cDNA clone CS0DK003YO17 of ... 118 2e-24 UniRef50_Q9UII7 Cluster: E-cadherin; n=5; Catarrhini|Rep: E-cadh... 118 2e-24 UniRef50_Q4T518 Cluster: Chromosome undetermined SCAF9471, whole... 117 4e-24 UniRef50_Q19194 Cluster: Cadherin family protein 5, isoform a; n... 117 4e-24 UniRef50_A5F7Q5 Cluster: Cadherin domain protein; n=23; Vibrio c... 117 5e-24 UniRef50_Q9VBV6 Cluster: CG13664-PA; n=5; Sophophora|Rep: CG1366... 116 7e-24 UniRef50_A7SLT3 Cluster: Predicted protein; n=2; Nematostella ve... 116 7e-24 UniRef50_Q8MY74 Cluster: Pf2-cadherin; n=1; Ptychodera flava|Rep... 116 9e-24 UniRef50_A7S5N8 Cluster: Predicted protein; n=1; Nematostella ve... 116 9e-24 UniRef50_P33545 Cluster: Desmocollin-2 precursor; n=7; Theria|Re... 116 9e-24 UniRef50_UPI0000F20971 Cluster: PREDICTED: hypothetical protein,... 115 2e-23 UniRef50_Q9YGQ8 Cluster: Cadherin; n=3; Coelomata|Rep: Cadherin ... 115 2e-23 UniRef50_Q4S7A6 Cluster: Chromosome 1 SCAF14716, whole genome sh... 115 2e-23 UniRef50_Q16Z56 Cluster: Cadherin, putative; n=1; Aedes aegypti|... 115 2e-23 UniRef50_UPI000155CE9C Cluster: PREDICTED: similar to reproducti... 114 3e-23 UniRef50_Q02413 Cluster: Desmoglein-1 precursor; n=19; Mammalia|... 114 3e-23 UniRef50_Q89NW9 Cluster: Bll3714 protein; n=2; cellular organism... 114 4e-23 UniRef50_Q8IXH8 Cluster: Cadherin-like protein 26 precursor; n=2... 113 7e-23 UniRef50_Q86SJ6 Cluster: Desmoglein-4 precursor; n=16; Mammalia|... 113 9e-23 UniRef50_Q02487 Cluster: Desmocollin-2 precursor; n=70; Mammalia... 113 9e-23 UniRef50_Q14126 Cluster: Desmoglein-2 precursor; n=18; Theria|Re... 112 1e-22 UniRef50_UPI0000E7FEEA Cluster: PREDICTED: similar to desmoglein... 112 2e-22 UniRef50_UPI0000E48655 Cluster: PREDICTED: similar to cadherin E... 111 2e-22 UniRef50_UPI0000ECCE39 Cluster: Desmoglein-1 precursor (Desmosom... 111 2e-22 UniRef50_Q4SDX5 Cluster: Chromosome undetermined SCAF14628, whol... 111 2e-22 UniRef50_Q4T0W5 Cluster: Chromosome 1 SCAF10821, whole genome sh... 111 3e-22 UniRef50_Q7UWZ8 Cluster: Putative uncharacterized protein; n=1; ... 111 3e-22 UniRef50_Q9VGW1 Cluster: Putative cadherin CG4509 precursor; n=3... 111 3e-22 UniRef50_Q5HZ99 Cluster: MGC85083 protein; n=2; Xenopus|Rep: MGC... 109 1e-21 UniRef50_UPI000155CFDF Cluster: PREDICTED: similar to protocadhe... 107 4e-21 UniRef50_UPI00004D6FF9 Cluster: Crumbs homolog 1 precursor.; n=2... 107 6e-21 UniRef50_Q4SDH3 Cluster: Chromosome undetermined SCAF14638, whol... 107 6e-21 UniRef50_Q7TSF1 Cluster: Desmoglein-1 beta precursor; n=4; Theri... 106 1e-20 UniRef50_Q7QAN5 Cluster: ENSANGP00000011927; n=1; Anopheles gamb... 105 2e-20 UniRef50_Q7TSF0 Cluster: Desmoglein-1 gamma precursor; n=5; Muri... 104 3e-20 UniRef50_A0NBP4 Cluster: ENSANGP00000031608; n=1; Anopheles gamb... 103 5e-20 UniRef50_UPI0000F20007 Cluster: PREDICTED: hypothetical protein;... 103 7e-20 UniRef50_Q7ULP1 Cluster: Probable G-cadherin-possibly involved i... 103 7e-20 UniRef50_UPI000155D1D0 Cluster: PREDICTED: hypothetical protein,... 103 9e-20 UniRef50_Q4SF34 Cluster: Chromosome 1 SCAF14609, whole genome sh... 103 9e-20 UniRef50_Q7UZ67 Cluster: Lipoprotein receptor-related protein; n... 103 9e-20 UniRef50_UPI0000F1D53E Cluster: PREDICTED: similar to cadherin 2... 102 1e-19 UniRef50_A4A1I4 Cluster: Fat protein-possibly involved in cell-c... 102 1e-19 UniRef50_UPI0000E8124F Cluster: PREDICTED: similar to oko meduzy... 101 2e-19 UniRef50_UPI0000E7FEE8 Cluster: PREDICTED: similar to desmocolli... 101 2e-19 UniRef50_UPI0001556456 Cluster: PREDICTED: similar to fat protei... 101 3e-19 UniRef50_UPI0000F2B3CC Cluster: PREDICTED: similar to crumbs hom... 100 7e-19 UniRef50_Q7QEU4 Cluster: ENSANGP00000019269; n=1; Anopheles gamb... 100 7e-19 UniRef50_Q1A5L1 Cluster: Crumbs-like protein 2b; n=5; Euteleosto... 99 9e-19 UniRef50_Q6ZTQ4 Cluster: Cadherin-like protein 28 precursor; n=1... 99 9e-19 UniRef50_UPI00006A1DB7 Cluster: Cadherin-like protein 26 precurs... 100 1e-18 UniRef50_UPI00004D822A Cluster: Cadherin-related tumor suppresso... 100 1e-18 UniRef50_Q4S5J7 Cluster: Chromosome 9 SCAF14729, whole genome sh... 99 2e-18 UniRef50_P32926 Cluster: Desmoglein-3 precursor; n=18; Eukaryota... 99 2e-18 UniRef50_Q7Q1N1 Cluster: ENSANGP00000013153; n=1; Anopheles gamb... 98 3e-18 UniRef50_O62328 Cluster: Putative uncharacterized protein cdh-7;... 98 3e-18 UniRef50_A7S4B9 Cluster: Predicted protein; n=1; Nematostella ve... 98 3e-18 UniRef50_Q5IJ48 Cluster: Crumbs homolog 2 precursor; n=17; Euthe... 98 4e-18 UniRef50_UPI00006600BE Cluster: Homolog of Homo sapiens "Desmogl... 97 6e-18 UniRef50_Q4SI11 Cluster: Chromosome 5 SCAF14581, whole genome sh... 97 6e-18 UniRef50_A7S9Y1 Cluster: Predicted protein; n=1; Nematostella ve... 97 6e-18 UniRef50_UPI0000D67092 Cluster: PREDICTED: hypothetical protein;... 97 8e-18 UniRef50_A4D0S4 Cluster: Laminin, beta 4; n=14; Eutheria|Rep: La... 97 8e-18 UniRef50_Q4SI27 Cluster: Chromosome 5 SCAF14581, whole genome sh... 96 1e-17 UniRef50_UPI0000660079 Cluster: Homolog of Homo sapiens "Laminin... 95 2e-17 UniRef50_A0YV99 Cluster: Cadherin domain protein; n=1; Lyngbya s... 95 2e-17 UniRef50_Q3B7G9 Cluster: Si:busm1-71b9.3 protein; n=5; Danio rer... 95 3e-17 UniRef50_Q8I722 Cluster: FAT-like cadherin CDH-3; n=3; Bilateria... 95 3e-17 UniRef50_Q21035 Cluster: Cadherin family protein 9; n=2; Caenorh... 95 3e-17 UniRef50_Q4SDX7 Cluster: Chromosome undetermined SCAF14628, whol... 94 4e-17 UniRef50_UPI0000DA2660 Cluster: PREDICTED: similar to FAT tumor ... 93 8e-17 UniRef50_UPI0000D5721D Cluster: PREDICTED: similar to CG4655-PA,... 93 8e-17 UniRef50_P55268 Cluster: Laminin subunit beta-2 precursor; n=69;... 93 1e-16 UniRef50_UPI00005C16EA Cluster: PREDICTED: similar to Protocadhe... 93 1e-16 UniRef50_Q58EP9 Cluster: LOC553337 protein; n=4; Danio rerio|Rep... 92 2e-16 UniRef50_Q4SNR1 Cluster: Chromosome 15 SCAF14542, whole genome s... 92 2e-16 UniRef50_O15230 Cluster: Laminin subunit alpha-5 precursor; n=16... 91 4e-16 UniRef50_Q21313 Cluster: Laminin-like protein epi-1 precursor; n... 91 5e-16 UniRef50_UPI000155C727 Cluster: PREDICTED: similar to laminin be... 89 1e-15 UniRef50_UPI0000F21093 Cluster: PREDICTED: similar to cadherin-l... 89 1e-15 UniRef50_UPI0000660623 Cluster: Homolog of Homo sapiens "Splice ... 89 2e-15 UniRef50_Q566L0 Cluster: Cdh26 protein; n=2; Xenopus tropicalis|... 89 2e-15 UniRef50_Q7YZI1 Cluster: MBCDH1; n=1; Monosiga brevicollis|Rep: ... 89 2e-15 UniRef50_Q61F88 Cluster: Putative uncharacterized protein CBG117... 89 2e-15 UniRef50_A2A3A3 Cluster: Protocadherin 15; n=10; Euarchontoglire... 89 2e-15 UniRef50_Q86DU3 Cluster: Cadherin-like protein; n=65; Ditrysia|R... 88 3e-15 UniRef50_Q171X1 Cluster: Putative uncharacterized protein; n=1; ... 88 3e-15 UniRef50_UPI0000D563F0 Cluster: PREDICTED: similar to CG15288-PB... 88 4e-15 UniRef50_Q9TVQ2 Cluster: Putative uncharacterized protein; n=2; ... 87 5e-15 UniRef50_UPI0000F1F39B Cluster: PREDICTED: similar to CDH26; n=2... 87 7e-15 UniRef50_Q6AX88 Cluster: MGC81969 protein; n=1; Xenopus laevis|R... 87 9e-15 UniRef50_UPI0000D5583D Cluster: PREDICTED: similar to Cadherin E... 86 1e-14 UniRef50_Q4SXH1 Cluster: Chromosome undetermined SCAF12413, whol... 86 1e-14 UniRef50_A2I7R3 Cluster: MadA; n=1; Mesorhizobium sp. R88B|Rep: ... 86 1e-14 UniRef50_Q4S162 Cluster: Chromosome 13 SCAF14769, whole genome s... 86 2e-14 UniRef50_Q09EY8 Cluster: Cadherin-like protein; n=4; Helicoverpa... 85 2e-14 UniRef50_UPI0000F2080D Cluster: PREDICTED: similar to Dsg2 prote... 85 3e-14 UniRef50_Q4RJQ1 Cluster: Chromosome 13 SCAF15035, whole genome s... 85 3e-14 UniRef50_A6ANU4 Cluster: Calx-beta domain family; n=1; Vibrio ha... 85 4e-14 UniRef50_UPI0000F1F613 Cluster: PREDICTED: similar to Desmoglein... 84 5e-14 UniRef50_Q1A5L2 Cluster: Oko meduzy; n=3; Clupeocephala|Rep: Oko... 84 6e-14 UniRef50_Q4S5K3 Cluster: Chromosome 9 SCAF14729, whole genome sh... 83 8e-14 UniRef50_Q32LQ8 Cluster: Pcdh2g6 protein; n=9; Clupeocephala|Rep... 83 8e-14 UniRef50_A0NQR0 Cluster: Fat protein-possibly involved in cell-c... 83 8e-14 UniRef50_UPI0000DA24E5 Cluster: PREDICTED: similar to FAT tumor ... 83 1e-13 UniRef50_UPI0000EBD4D8 Cluster: PREDICTED: similar to Laminin al... 83 1e-13 UniRef50_UPI0000DA3D77 Cluster: PREDICTED: similar to FAT tumor ... 82 2e-13 UniRef50_Q6TM00 Cluster: Protocadherin-like protein; n=3; Tetrao... 82 2e-13 UniRef50_A7S7D3 Cluster: Predicted protein; n=1; Nematostella ve... 82 2e-13 UniRef50_UPI00015B61BF Cluster: PREDICTED: similar to laminin A ... 82 2e-13 UniRef50_UPI00015B59C9 Cluster: PREDICTED: similar to laminin al... 81 3e-13 UniRef50_UPI0000DB6CE4 Cluster: PREDICTED: similar to wing blist... 81 3e-13 UniRef50_Q967S8 Cluster: Laminin beta chain; n=1; Schistocerca g... 81 3e-13 UniRef50_Q4S5A4 Cluster: Chromosome 19 SCAF14731, whole genome s... 81 4e-13 UniRef50_A0LXF0 Cluster: Secreted protein containing cadherin do... 80 8e-13 UniRef50_UPI0000DA41C0 Cluster: PREDICTED: similar to desmocolli... 80 1e-12 UniRef50_UPI000155551A Cluster: PREDICTED: similar to Ksp-cadher... 79 1e-12 UniRef50_Q8JHV6 Cluster: Laminin beta 4; n=7; Clupeocephala|Rep:... 79 1e-12 UniRef50_UPI0000E814A8 Cluster: PREDICTED: similar to MEGF6; n=1... 79 2e-12 UniRef50_Q5BYL9 Cluster: SJCHGC04271 protein; n=1; Schistosoma j... 78 3e-12 UniRef50_Q2Q1W5 Cluster: Laminin alpha 5; n=7; Clupeocephala|Rep... 78 4e-12 UniRef50_UPI0000D5583E Cluster: PREDICTED: similar to CG3389-PA;... 77 5e-12 UniRef50_O75093 Cluster: Slit homolog 1 protein precursor; n=144... 77 5e-12 UniRef50_UPI0000E4A0C7 Cluster: PREDICTED: similar to fibropelli... 77 7e-12 UniRef50_UPI0000DB7BBA Cluster: PREDICTED: similar to Laminin B1... 77 9e-12 UniRef50_Q4T7X6 Cluster: Chromosome undetermined SCAF7949, whole... 77 9e-12 UniRef50_Q9BPS2 Cluster: Laminin; n=1; Bombyx mori|Rep: Laminin ... 77 9e-12 UniRef50_UPI0000F2DD8E Cluster: PREDICTED: hypothetical protein;... 76 1e-11 UniRef50_UPI000051A338 Cluster: PREDICTED: similar to agrin isof... 76 1e-11 UniRef50_Q0APJ1 Cluster: Cadherin precursor; n=1; Maricaulis mar... 76 1e-11 UniRef50_Q60JK4 Cluster: Putative uncharacterized protein CBG244... 76 2e-11 UniRef50_Q8NHD4 Cluster: SREC-3; n=6; Theria|Rep: SREC-3 - Homo ... 76 2e-11 UniRef50_Q14162 Cluster: Endothelial cells scavenger receptor pr... 76 2e-11 UniRef50_UPI0000EBD4DB Cluster: PREDICTED: similar to cadherin 4... 75 2e-11 UniRef50_Q304D6 Cluster: Putative uncharacterized protein; n=4; ... 75 3e-11 UniRef50_A7SQA1 Cluster: Predicted protein; n=1; Nematostella ve... 75 3e-11 UniRef50_A7SD81 Cluster: Predicted protein; n=1; Nematostella ve... 75 3e-11 UniRef50_UPI0000E7F7D9 Cluster: PREDICTED: hypothetical protein;... 75 4e-11 UniRef50_A7SIF3 Cluster: Predicted protein; n=1; Nematostella ve... 75 4e-11 UniRef50_O75445 Cluster: Usherin precursor; n=34; Eukaryota|Rep:... 75 4e-11 UniRef50_UPI00015B51E9 Cluster: PREDICTED: similar to laminin ga... 74 5e-11 UniRef50_UPI00005A0191 Cluster: PREDICTED: similar to protocadhe... 74 5e-11 UniRef50_A0NB14 Cluster: ENSANGP00000025533; n=1; Anopheles gamb... 74 5e-11 UniRef50_UPI0000E4975D Cluster: PREDICTED: similar to ENSANGP000... 74 7e-11 UniRef50_UPI0000660B21 Cluster: Homolog of Brachydanio rerio "E-... 74 7e-11 UniRef50_Q4SW86 Cluster: Chromosome undetermined SCAF13670, whol... 74 7e-11 UniRef50_A4A585 Cluster: Repeat domain protein; n=1; Congregibac... 74 7e-11 UniRef50_P25391 Cluster: Laminin subunit alpha-1 precursor; n=34... 74 7e-11 UniRef50_UPI0000D9CA40 Cluster: PREDICTED: similar to Cadherin E... 73 9e-11 UniRef50_Q45H72 Cluster: Laminin alpha 1; n=9; Euteleostomi|Rep:... 73 9e-11 UniRef50_A7SYG4 Cluster: Predicted protein; n=1; Nematostella ve... 73 9e-11 UniRef50_O75095 Cluster: Multiple epidermal growth factor-like d... 73 9e-11 UniRef50_Q00174 Cluster: Laminin subunit alpha precursor; n=7; D... 73 9e-11 UniRef50_UPI0000E4A783 Cluster: PREDICTED: similar to laminin ga... 73 1e-10 UniRef50_O45614 Cluster: Putative uncharacterized protein lam-3;... 73 1e-10 UniRef50_A7SSY8 Cluster: Predicted protein; n=1; Nematostella ve... 73 1e-10 UniRef50_UPI0000DB7F08 Cluster: PREDICTED: similar to Laminin A ... 73 2e-10 UniRef50_Q4C8Z4 Cluster: VCBS; n=1; Crocosphaera watsonii WH 850... 73 2e-10 UniRef50_Q18823 Cluster: Laminin-like protein lam-2 precursor; n... 73 2e-10 UniRef50_UPI0000DA39A7 Cluster: PREDICTED: similar to Crumbs hom... 72 2e-10 UniRef50_A6BZA6 Cluster: VCBS; n=1; Planctomyces maris DSM 8797|... 72 2e-10 UniRef50_UPI0000F203FC Cluster: PREDICTED: similar to usherin; n... 72 3e-10 UniRef50_UPI0000D9C9E0 Cluster: PREDICTED: similar to Cadherin E... 71 4e-10 UniRef50_A7S9Y4 Cluster: Predicted protein; n=1; Nematostella ve... 71 4e-10 UniRef50_Q4S226 Cluster: Chromosome undetermined SCAF14764, whol... 71 5e-10 UniRef50_A7SIF6 Cluster: Predicted protein; n=1; Nematostella ve... 71 5e-10 UniRef50_A7RRT9 Cluster: Predicted protein; n=1; Nematostella ve... 71 5e-10 UniRef50_A7RNY3 Cluster: Predicted protein; n=4; Nematostella ve... 71 5e-10 UniRef50_UPI0000F204F9 Cluster: PREDICTED: hypothetical protein;... 71 6e-10 UniRef50_UPI0000EBE0CA Cluster: PREDICTED: similar to laminin be... 71 6e-10 UniRef50_UPI0000E48844 Cluster: PREDICTED: similar to Usher synd... 71 6e-10 UniRef50_Q4TB23 Cluster: Chromosome 15 SCAF7210, whole genome sh... 71 6e-10 UniRef50_A7SV36 Cluster: Predicted protein; n=1; Nematostella ve... 71 6e-10 UniRef50_A7RIY4 Cluster: Predicted protein; n=1; Nematostella ve... 70 8e-10 UniRef50_P15215 Cluster: Laminin subunit gamma-1 precursor; n=16... 70 8e-10 UniRef50_P11046 Cluster: Laminin subunit beta-1 precursor; n=6; ... 70 8e-10 UniRef50_UPI00006A069F Cluster: MEGF11 protein; n=2; Xenopus tro... 70 1e-09 UniRef50_Q4T0S1 Cluster: Chromosome undetermined SCAF10875, whol... 70 1e-09 UniRef50_UPI0000E45F7B Cluster: PREDICTED: similar to MEGF6; n=4... 69 1e-09 UniRef50_UPI0000D99687 Cluster: PREDICTED: similar to agrin; n=1... 69 1e-09 UniRef50_UPI0000F3484D Cluster: UPI0000F3484D related cluster; n... 69 1e-09 UniRef50_Q8IQ18 Cluster: CG33196-PB; n=10; Endopterygota|Rep: CG... 69 1e-09 UniRef50_Q9Y6N6 Cluster: Laminin subunit gamma-3 precursor; n=31... 69 1e-09 UniRef50_UPI00006A00A9 Cluster: Laminin subunit gamma-2 precurso... 69 2e-09 UniRef50_A1XQX6 Cluster: Neurexin 2b alpha; n=4; Clupeocephala|R... 69 2e-09 UniRef50_UPI00015B4CFA Cluster: PREDICTED: similar to IP15264p; ... 68 3e-09 UniRef50_UPI00015A7BCD Cluster: UPI00015A7BCD related cluster; n... 68 3e-09 UniRef50_P46531 Cluster: Neurogenic locus notch homolog protein ... 68 3e-09 UniRef50_UPI0000E4975E Cluster: PREDICTED: similar to laminin A ... 68 4e-09 UniRef50_UPI0000519B12 Cluster: PREDICTED: similar to wing blist... 68 4e-09 UniRef50_UPI000065F871 Cluster: Homolog of Homo sapiens "MEGF10 ... 68 4e-09 UniRef50_Q4SLY2 Cluster: Chromosome 13 SCAF14555, whole genome s... 68 4e-09 UniRef50_Q4RVG6 Cluster: Chromosome 15 SCAF14992, whole genome s... 68 4e-09 UniRef50_Q17L45 Cluster: Laminin alpha-1, 2 chain; n=3; Culicida... 68 4e-09 UniRef50_UPI000155D0E5 Cluster: PREDICTED: similar to intestinal... 67 6e-09 >UniRef50_Q9V5N8 Cluster: Protocadherin-like wing polarity protein stan precursor; n=10; Sophophora|Rep: Protocadherin-like wing polarity protein stan precursor - Drosophila melanogaster (Fruit fly) Length = 3574 Score = 2285 bits (5668), Expect = 0.0 Identities = 1104/1828 (60%), Positives = 1339/1828 (73%), Gaps = 84/1828 (4%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 Q+NVLDCNDHSP FE +Q+EAS+REGA+ G+TV+TL+ATDQDIGKNAE+EY IE VT Sbjct: 451 QVNVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGA 510 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 +D +FRID RSG + TR+SLDRE Y +LV A D AS S+R Sbjct: 511 GLAQDQE----------MPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSER 560 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI-SVTDNPVIAKIKATDADVGANSAIR 188 ++TA++ V ++DDNDNYPQFSE+TYTV V ED T++ +A I+ATDAD G N+AIR Sbjct: 561 RTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIR 620 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 YAIIGGNTQ QFSIDS+SGDVSLVK LDYE VRSYRLVIRAQDGGSPSRSNTTQLL+N+ Sbjct: 621 YAIIGGNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVI 680 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D NDNAPRFYTS FQESV ENVP+GY+I+RVQAYD+DEG NAE+TY+++++D + P Sbjct: 681 DANDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDD----NFP 736 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 + +DPR+GWV T LDRE Q ++ V A DGG PP+SA+++ F P Sbjct: 737 LAVDPRTGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNP 796 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 YE + ED+PPGTPV T+TATD DED+RLHYEIT GNTRGRF+ITSQNGRGLIT+AQ Sbjct: 797 KYYEANVGEDQPPGTPVTTVTATDPDEDSRLHYEITTGNTRGRFAITSQNGRGLITIAQS 856 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 LD+KQE+R++LTV+ATDSGGRSDTA V INITDANN+AP+FENAPY+ASVFEDAP+GTTV Sbjct: 857 LDYKQEKRFLLTVAATDSGGRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVGTTV 916 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 LVVSATDSDVG+NAQITYSL+ E N + D F INPQTGAI TN LDRET SGYL Sbjct: 917 LVVSATDSDVGVNAQITYSLNEESIN-GLGSPDP-FSINPQTGAIVTNAPLDRETTSGYL 974 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 LTVTA+DGG PSLSDTTDVEI V DVNDN P FK LY A+I+EDALVGTSV QV A+D Sbjct: 975 LTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDP 1034 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 DVGLNGRI Y L +D E+GSFVIDP SG IRTNK LDRESVA L A+A+D G+PP S Sbjct: 1035 DVGLNGRIKYLLSDRDIEDGSFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLS 1094 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 STV V I++ED+NDSPP F SD +T Y+ ENSP+G+ +GEI AHDPDEG NAVVHYSI G Sbjct: 1095 STVEVQIRLEDVNDSPPTFASDKITLYVPENSPVGSVVGEIHAHDPDEGVNAVVHYSIIG 1154 Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVN 788 GDDSN+FSL TR GS++A+L+TM +LDYES RK++ELV+RAASPPL ND +EILVTDVN Sbjct: 1155 GDDSNAFSLVTRPGSERAQLLTMTELDYESTRKRFELVVRAASPPLRNDAHIEILVTDVN 1214 Query: 789 DNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGS 848 DNAPV++DFQ+IFNN++D FP G GR+PA+DADV+DKL YRILSGNNANL+ LN ++G Sbjct: 1215 DNAPVLRDFQVIFNNFRDHFPSGEIGRIPAFDADVSDKLHYRILSGNNANLLRLNSSSGG 1274 Query: 849 MTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQF 908 + LSPQLNTNVPK ATMEVSV+DG+NE KA+MQLSVRLITE+ML NS+TVRLN+MT E F Sbjct: 1275 LVLSPQLNTNVPKFATMEVSVSDGINEAKAIMQLSVRLITEDMLFNSVTVRLNEMTEEAF 1334 Query: 909 LSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSP 968 LSPLL FF+DGLAAIIPCPKE+I++FS+QDDTDV+ ILNVSFSARRPD Sbjct: 1335 LSPLLNFFLDGLAAIIPCPKEHIFVFSIQDDTDVSSRILNVSFSARRPDVS------HEE 1388 Query: 969 HYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNS 1028 Y+P +L+ERVYL+R LARLATV+VLPFDDN+CV EPCLNFEECLTVLKFGNAS F++S Sbjct: 1389 FYTPQYLQERVYLNRAILARLATVEVLPFDDNLCVREPCLNFEECLTVLKFGNASEFIHS 1448 Query: 1029 DSVLFRPIYPVTSFTCQCPEGFTGVN----CETILTKASCEVDGDGSIC---RSGSQCVA 1081 D+VLFRPIYPV +F C CPEGFTG C+T + + +G C G CV Sbjct: 1449 DTVLFRPIYPVNTFACSCPEGFTGSKEHYLCDTEVDLCYSDPCQNGGTCVRREGGYTCVC 1508 Query: 1082 RR----------------------EGGILCQGC--SIDAAYTTAVCELRARSFPVSSFLT 1117 EGG+ C S TA CELRAR+F +SFLT Sbjct: 1509 PSTHTGQNCETGVGHLRPCPSETCEGGLSCLSNYPSSQPPPYTATCELRARAFGRNSFLT 1568 Query: 1118 FPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRGGGPGLRFSFS 1177 F LK+RHR +LKL+FAT +GLLLYNGRYNE HDF+ALE+ FSFS Sbjct: 1569 FESLKQRHRFNLKLRFATVQENGLLLYNGRYNELHDFIALEIHEGHVS--------FSFS 1620 Query: 1178 LGGGKSEITV--EGNVGDGSWHTVEIEYFNRTITMILDDCDKVLSLAGAADFGLKYACAN 1235 LG I+V E V DG WH VE+ Y NR++T++LD+CD ++L+G G +++CAN Sbjct: 1621 LGDHSERISVIQEAKVSDGKWHQVEVVYLNRSVTLVLDNCDTAIALSG--QLGDRWSCAN 1678 Query: 1236 FTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNKDFVGCISDFYIDHKFI 1295 T L RC + TETCHRFLDLTGPLQ+GGLP IP+ F V N+DFVGCISD ID +F+ Sbjct: 1679 RTTLKLDKRCSLLTETCHRFLDLTGPLQVGGLPRIPAHFPVTNRDFVGCISDLRIDDRFV 1738 Query: 1296 DLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPP 1355 DLNSYVADNGTLAGCP+K C S PC+NG C + W TY C+C EG+ G C D+ P Sbjct: 1739 DLNSYVADNGTLAGCPQKAPLCQSEPCFNGGTCREGWGTYSCECPEGYAGNSCQDNIPAP 1798 Query: 1356 WRFGGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMSIQ----------LKSGLLHYS 1405 WRF GDG LSFNPLLRPIQLPW + S+RTRQ++AF++ IQ L+ G+L+Y Sbjct: 1799 WRFSGDGSLSFNPLLRPIQLPWTTSFSLRTRQKEAFLLQIQIGQNSSAAVCLRQGVLYYI 1858 Query: 1406 YNGETMYLPMATLSDGAWHRIEIKW-LGTDISVTVDYGLRTVLMPMLANKIQGQYIGKIL 1464 ++GE MYL A LSDG WHR+EI+W G++I +VDYG R+ +PM + K+QG Y+GKI+ Sbjct: 1859 FDGEPMYLAGAFLSDGEWHRVEIRWQQGSEIHFSVDYGQRSGSVPM-SQKVQGLYVGKIV 1917 Query: 1465 IGGLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRPTVRENVRDGCQSRADCMLSICPP 1524 +G D + G + + FEGCIQDVRIG QS+L+RPT+RENV DGC+SRA C CP Sbjct: 1918 MGSPDGSIGAV-PEASPFEGCIQDVRIGAGQSVLSRPTIRENVEDGCESRAQCP-DHCPN 1975 Query: 1525 YSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARCVPDQT-PKGYSCACEPGYTLTT 1583 +S C +SWD STC C++G VG C C + PC + C + + P+GY C C + Sbjct: 1976 HSSCQSSWDLSTCECDSGYVGTDCAPICTVRPCASGVCRANTSLPRGYDCECNSS-SRHG 2034 Query: 1584 SGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLP 1643 C + ++ CPGGWWG CGPC CD+ +GYHP CNK G+C+CK NHY+P CL Sbjct: 2035 DYCEKELQQPCPGGWWGERVCGPCRCDLAQGYHPDCNKTTGQCYCKTNHYQPPNETACLS 2094 Query: 1644 CQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAG 1703 C CY+ GS + +C TGQC CR GVIGR CD+C+N YAEVT SGCEVVYD CPRSFAG Sbjct: 2095 CDCYSIGSFSGACNPLTGQCECREGVIGRRCDSCSNPYAEVT-LSGCEVVYDACPRSFAG 2153 Query: 1704 GVWWPRTKFGVETITDCPPGSSGRATRTCDETKDVPWQDPDMFNCTTATFYQLRKQLHKI 1763 GVWWPRT G I CPP + G+ R+CD + W PDM+NCT+ F +LR+QL ++ Sbjct: 2154 GVWWPRTPLGGVAIEGCPPPARGKGQRSCD-VQSGSWNTPDMYNCTSEPFVELRRQLSQL 2212 Query: 1764 ETGELTMNTFVGVRVAADLSTACANTPR 1791 E EL +N+FV +++A L AC R Sbjct: 2213 EKLELELNSFVAIKMAEQLRKACEAVDR 2240 Score = 363 bits (893), Expect = 4e-98 Identities = 275/861 (31%), Positives = 417/861 (48%), Gaps = 69/861 (8%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 + + SP FE Y ASV E +G V T++A D + ++ V Y++ L+ Sbjct: 351 ELRNQSPYFEQALYVASVLEEQPAGAAVTTVRARDPE---DSPVVYSM----VSLLDSRS 403 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134 Q +F++D R+G + T ASLDRE + + V ATD + P S T Sbjct: 404 ------------QSLFKVDSRTGVVTTSASLDRELMDVHYFRVVATDDSFPPR---SGTT 448 Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII-- 192 T+ VN++D ND+ P F + + S+ E +V + ++ATD D+G N+ I Y I Sbjct: 449 TLQVNVLDCNDHSPTFEAEQFEASIREGATV--GSTVITLRATDQDIGKNAEIEYGIEAV 506 Query: 193 ---GGNTQMQ----FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD---GGSPSRSNTTQ 242 G Q Q F IDS SG +S +LD E SY L++ A D S R+ T Sbjct: 507 TDGAGLAQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATAS 566 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIG---YSIVRVQAYDADEGVNAELTYTMTDK 299 + + + D NDN P+F + V E+ G ++ ++A DAD+G NA + Y + Sbjct: 567 VQVKVLDDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIG- 625 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 GN +ID SG V LD E+ Y+L++ A DGG P RS T Sbjct: 626 ---GNTQSQFSIDSMSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDA 682 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG 419 F Q++ + E+ P G ++ + A D+DE + F + Sbjct: 683 NDNAPRFYTSQFQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLAVDPR 742 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477 G + +PLD +++ R+ V A D G +S ++ V I + D N+ P F Y A+ Sbjct: 743 TGWVQTIKPLDREEQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEAN 802 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 V ED P GT V V+ATD D ++++ Y +++ + A Q G IT + Sbjct: 803 VGEDQPPGTPVTTVTATDPDE--DSRLHYEITTGNTRGRFAITSQN-----GRGLITIAQ 855 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LD + +LLTV A D G SDT V I++ D N+ P+F+ Y+A++ EDA VG Sbjct: 856 SLDYKQEKRFLLTVAATDSG--GRSDTATVHINITDANNFAPIFENAPYSASVFEDAPVG 913 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKD-REEGS---FVIDPASGVIRTNKALDRESVATH 653 T+V V ATD+DVG+N +I Y L+ + GS F I+P +G I TN LDRE+ + + Sbjct: 914 TTVLVVSATDSDVGVNAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGY 973 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713 L A DGG P S T V I + D+ND+ P F+S I E++ +GT++ ++ A D Sbjct: 974 LLTVTAKDGGNPSLSDTTDVEIGVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASD 1033 Query: 714 PDEGPNAVVHYSIKGGD-DSNSFSLETRQGSDKAELVTMVDLDYESPRKKY--ELVIRAA 770 PD G N + Y + D + SF ++ G+ + T LD ES + + + Sbjct: 1034 PDVGLNGRIKYLLSDRDIEDGSFVIDPTSGT----IRTNKGLDRESVAVFHLTAIAVDKG 1089 Query: 771 SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDAD--VTDKL 827 SPPL + V V+I + DVND+ P +I + PVG G + A+D D V + Sbjct: 1090 SPPLSSTVEVQIRLEDVNDSPPTFASDKITL-YVPENSPVGSVVGEIHAHDPDEGVNAVV 1148 Query: 828 QYRILSGNNANLILLNETTGS 848 Y I+ G+++N L GS Sbjct: 1149 HYSIIGGDDSNAFSLVTRPGS 1169 Score = 358 bits (880), Expect = 1e-96 Identities = 257/769 (33%), Positives = 391/769 (50%), Gaps = 52/769 (6%) Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 P F + Y SV E+ + ++A D + +++ +Q F +DS +G Sbjct: 357 PYFEQALYVASVLEEQPA--GAAVTTVRARDPEDSPVVYSMVSLLDSRSQSLFKVDSRTG 414 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 V+ +LD E + + + A D P RS TT L +N+ D ND++P F F+ S+ Sbjct: 415 VVTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFEAEQFEASIR 474 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTY---TMTD-KDYTGNVDLPI-TIDPRSGWVYTSG 322 E +G +++ ++A D D G NAE+ Y +TD + ++PI ID RSG + T Sbjct: 475 EGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDSRSGVISTRS 534 Query: 323 QLDRETQAKYQLLVTATD---GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE 379 LDRET Y LLVTA D R+ATA+ F Y V++ ED+ Sbjct: 535 SLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSERTYTVQVPEDQ 594 Query: 380 PPGT---PVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434 GT V + ATDAD+ N + Y I GGNT+ +FSI S +G +++ +PLD++ Sbjct: 595 WGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQFSIDSMSGD--VSLVKPLDYESV 652 Query: 435 RRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492 R Y L + A D G RS+T + +N+ DAN+ AP F + + SV E+ P+G ++ V Sbjct: 653 RSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQESVLENVPVGYNIIRVQ 712 Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552 A DSD G NA+ITYS+S N +A ++P+TG + T K LDRE + V Sbjct: 713 AYDSDEGANAEITYSISERDDNFPLA-------VDPRTGWVQTIKPLDREEQGRFAFQVV 765 Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612 A+DGGVP S ++ V I+V DVNDN+P F + Y AN+ ED GT V+ V ATD D Sbjct: 766 AKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTTVTATDPDE-- 823 Query: 613 NGRIHYELDPKDREEGSFVIDPAS--GVIRTNKALDRESVATHDLKAVAIDGGTPPQSST 670 + R+HYE+ G F I + G+I ++LD + L A D G +S T Sbjct: 824 DSRLHYEI-TTGNTRGRFAITSQNGRGLITIAQSLDYKQEKRFLLTVAATDSG--GRSDT 880 Query: 671 VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY-----S 725 VHI I D N+ P+FE+ + + E++P+GTT+ + A D D G NA + Y S Sbjct: 881 ATVHINITDANNFAPIFENAPYSASVFEDAPVGTTVLVVSATDSDVGVNAQITYSLNEES 940 Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEI 782 I G + FS+ + G+ +VT LD E+ Y L + A +P L + VEI Sbjct: 941 INGLGSPDPFSINPQTGA----IVTNAPLDRET-TSGYLLTVTAKDGGNPSLSDTTDVEI 995 Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNA--N 838 VTDVNDNAP K + +D +V A D DV +++Y +LS + Sbjct: 996 GVTDVNDNAPAFKSPLYQASILEDALVGTSVIQVAASDPDVGLNGRIKY-LLSDRDIEDG 1054 Query: 839 LILLNETTGSMTLSPQLN-TNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886 +++ T+G++ + L+ +V ++V G + + +++ +RL Sbjct: 1055 SFVIDPTSGTIRTNKGLDRESVAVFHLTAIAVDKGSPPLSSTVEVQIRL 1103 Score = 268 bits (656), Expect = 2e-69 Identities = 203/656 (30%), Positives = 322/656 (49%), Gaps = 50/656 (7%) Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 R++ + +P F +L+ SV E P G ++ V+A D ++ + + Y+M + + L Sbjct: 350 RELRNQSPYFEQALYVASVLEEQPAGAAVTTVRARDPED---SPVVYSMVSLLDSRSQSL 406 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 +D R+G V TS LDRE + V ATD PPRS T T F Sbjct: 407 -FKVDSRTGVVTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQVNVLDCNDHSPTFE 465 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHY---EITGGNTRGR------FSITS 416 Q+E + E G+ V+TL ATD D ++ + Y +T G + F I S Sbjct: 466 AEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGLAQDQEMPIFRIDS 525 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATD-----SGGRSDTAMVQINITDANNYAPVFEN 471 ++ G+I+ LD + Y L V+A D S R+ TA VQ+ + D N+ P F Sbjct: 526 RS--GVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVLDDNDNYPQFSE 583 Query: 472 APYTASVFEDAPIGT---TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528 YT V ED GT TV + ATD+D G NA I Y++ + QF I+ Sbjct: 584 RTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIG-------GNTQSQFSIDS 636 Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588 +G ++ K LD E++ Y L + A+DGG PS S+TT + ++V+D NDN P F + Sbjct: 637 MSGDVSLVKPLDYESVRSYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAPRFYTSQFQE 696 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648 +++E+ VG ++ +V A D+D G N I Y + +D + +DP +G ++T K LDRE Sbjct: 697 SVLENVPVGYNIIRVQAYDSDEGANAEITYSISERD-DNFPLAVDPRTGWVQTIKPLDRE 755 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 + VA DGG PP+S++ V I ++D+ND+ P F + E+ P GT + Sbjct: 756 EQGRFAFQVVAKDGGVPPKSASSSVVITVQDVNDNDPAFNPKYYEANVGEDQPPGTPVTT 815 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVI 767 + A DPDE ++ +HY I G+ F++ ++ G L+T+ LDY+ K++ L + Sbjct: 816 VTATDPDE--DSRLHYEITTGNTRGRFAITSQNGRG---LITIAQSLDYKQ-EKRFLLTV 869 Query: 768 RAASPPLWND-VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR-VPAYDADV-- 823 A +D V I +TD N+ AP+ ++ + ++D PVG V A D+DV Sbjct: 870 AATDSGGRSDTATVHINITDANNFAPIFENAPYSASVFEDA-PVGTTVLVVSATDSDVGV 928 Query: 824 ----TDKLQYRILSG-NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN 874 T L ++G + + +N TG++ + L+ + V+ DG N Sbjct: 929 NAQITYSLNEESINGLGSPDPFSINPQTGAIVTNAPLDRETTSGYLLTVTAKDGGN 984 Score = 231 bits (566), Expect = 2e-58 Identities = 122/282 (43%), Positives = 186/282 (65%), Gaps = 31/282 (10%) Query: 1791 RLYGADVVVAEGILLELMDYELRQAGLNLTHSQDKDYVRNLLKSTNTILNVEYEREWKRI 1850 RLYGAD++V EG+L EL++YEL Q+GLNL+HSQDK +++NL+ + + IL+ +YE EW+R Sbjct: 2293 RLYGADLLVTEGLLQELINYELMQSGLNLSHSQDKYFIKNLVDAASVILDRKYEAEWRRA 2352 Query: 1851 RELTGHGAELLVQKFDEYIAVLAESQHDTYTSPFEIVTKDVVISVDTVTSESIYGFEPTQ 1910 EL G + LV F++Y+ VLA SQHDTYTSPFEIV ++ + +D VT+ES++G+EP Q Sbjct: 2353 TELIQRGPDDLVDAFNKYLVVLARSQHDTYTSPFEIVQPNMALGLDIVTTESLFGYEPEQ 2412 Query: 1911 LNR------LNVDSYTTERVVALPDTSAFI-HSPIQAXXXXXXXXXXXXXXXXXXXVSFP 1963 L+ L +++TTE VV LPDTS F+ HS Q +SFP Sbjct: 2413 LSEYHRSKYLKPNAFTTESVV-LPDTSGFLQHSARQ-----------------RPVISFP 2454 Query: 1964 KYNNYVRSKNKFDKYTRVLLPLDLLGISNNNLQDITD-----TNYETRAVFGYVQYSRNS 2018 KYNNY+ + KFD++T+VL+PL++LGI+ +I+ ++++ RA+ Y QY ++ Sbjct: 2455 KYNNYILDRRKFDQHTKVLVPLEMLGITPPESDEISQSGRRGSSHDHRAIVAYAQY-KDV 2513 Query: 2019 SQLMPLRMDDSVSLRWGVNITIGSPILQIAVFVPESIWTRET 2060 QL+P D++++ RWGV++ + +PIL + + VP +ET Sbjct: 2514 GQLLPDLYDETITRRWGVDVELATPILSLQILVPSMEREQET 2555 Score = 200 bits (488), Expect = 4e-49 Identities = 146/445 (32%), Positives = 225/445 (50%), Gaps = 34/445 (7%) Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509 +DT + + + N +P FE A Y ASV E+ P G V V A D + ++ + YS+ Sbjct: 340 NDTDIARRVRRELRNQSPYFEQALYVASVLEEQPAGAAVTTVRARDPE---DSPVVYSMV 396 Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569 S + + + F ++ +TG +TT+ LDRE M + V A D P S TT +++ Sbjct: 397 SLLDSRS----QSLFKVDSRTGVVTTSASLDRELMDVHYFRVVATDDSFPPRSGTTTLQV 452 Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD-------- 621 +V+D ND+ P F+ + + A+I E A VG++V + ATD D+G N I Y ++ Sbjct: 453 NVLDCNDHSPTFEAEQFEASIREGATVGSTVITLRATDQDIGKNAEIEYGIEAVTDGAGL 512 Query: 622 PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID---GGTPPQSSTVIVHIKIE 678 +D+E F ID SGVI T +LDRE+ ++ L A D + +++T V +K+ Sbjct: 513 AQDQEMPIFRIDSRSGVISTRSSLDRETSDSYHLLVTAADLASAQSERRTATASVQVKVL 572 Query: 679 DINDSPPVFESDCLTFYISENSPIGT---TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735 D ND+ P F T + E+ GT T+ IRA D D+G NA + Y+I GG+ + F Sbjct: 573 DDNDNYPQFSERTYTVQVPEDQWGGTEDNTVAHIRATDADQGNNAAIRYAIIGGNTQSQF 632 Query: 736 SLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792 S+++ G ++ + LDYES R Y LVIRA SP N ++ + V D NDNAP Sbjct: 633 SIDSMSG----DVSLVKPLDYESVR-SYRLVIRAQDGGSPSRSNTTQLLVNVIDANDNAP 687 Query: 793 VMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTG-S 848 Q + + PVG RV AYD+D ++ Y I ++ + ++ TG Sbjct: 688 RFYTSQ-FQESVLENVPVGYNIIRVQAYDSDEGANAEITYSISERDDNFPLAVDPRTGWV 746 Query: 849 MTLSPQLNTNVPKLATMEVSVTDGV 873 T+ P + A V+ GV Sbjct: 747 QTIKPLDREEQGRFAFQVVAKDGGV 771 Score = 176 bits (429), Expect = 6e-42 Identities = 80/167 (47%), Positives = 123/167 (73%), Gaps = 6/167 (3%) Query: 2167 MYRSLSGIRLKKPIRLQIWLDINRETFGSRTNPQCVHWSTLRGSGEWSRVGCHTEI---D 2223 +YRSL L +PI+LQ+WLD++ FG R+NPQCV W++ + +W+R+GC TEI D Sbjct: 2713 VYRSLGSPHLAQPIKLQMWLDVDSARFGPRSNPQCVRWNSF--TNQWTRLGCQTEIPDFD 2770 Query: 2224 YDWSPYSEEPLLINCTCNHLSTFAVLVDEVDVEFIPEPSLLESVTSYTAFSISLPLLLTS 2283 D++P +++ +L+NC+C H+S++AV+VD +D E IPEPSLL +TSY+AF +SLPLLL Sbjct: 2771 GDFNPAAQQAILVNCSCTHISSYAVIVDVIDPEDIPEPSLLVQITSYSAFLVSLPLLLGV 2830 Query: 2284 WAALCLIRGGAATVSNSIHKHLIFSVFMAELLYLIALKARTSLVQNE 2330 AL L+R G T SN+IH++++ VF AELL+ + +++R L+++E Sbjct: 2831 LLALALLR-GQQTNSNTIHQNIVLCVFCAELLFFVGMQSRRQLLESE 2876 Score = 142 bits (344), Expect = 1e-31 Identities = 105/326 (32%), Positives = 150/326 (46%), Gaps = 18/326 (5%) Query: 2330 EPVVWWVVIPXXXXXXXXXXXXXXXXXXXFTVRDHVTGFGNLRMLLAVSIVCLPLLCVAW 2389 EPVVWW+V P FT++DHV GFGNLR LL +S+V LPL+ V W Sbjct: 2957 EPVVWWLVGPIAGMSVVNLLILFVSVKAAFTLKDHVLGFGNLRTLLWLSVVSLPLMGVMW 3016 Query: 2390 ASALLLGSEAGGRRXXXXXXXXXXXXXXXIAASLGYIAFNVRVRDNLKRTVLRCMGKKVP 2449 A+L SE + +GY N RVR+NL+RT LRCMG+KVP Sbjct: 3017 VLAVLAASE---HSQLLSLLLSGVVLLHALFCLIGYCIINKRVRENLQRTCLRCMGRKVP 3073 Query: 2450 LADTSVIISSSAHNLSQVNRSSLAYHSSTEPGRQMRNIGIXXXXXXXXXXXXXXXXXXXX 2509 L D+S+++S+S+HN++ R S + +S RNIGI Sbjct: 3074 LLDSSMVVSNSSHNVNAAARPS-NFLASGYDTTTRRNIGI--SASSTTSRSTAKTSSSPY 3130 Query: 2510 XDGQLRHXXXXXXXXXXXASDMPAYLRGFDSSLHTR-KDGERIAS--GSANSYLPNITEG 2566 DGQLR ASD P++LRGF+SS R + GE S +S + T+G Sbjct: 3131 SDGQLRQ-TSTSTSNYNSASDAPSFLRGFESSTTGRSRGGEEKPSRRQRKDSDSGSETDG 3189 Query: 2567 APLAMSPRWPSHVREDQSRPEMGRWSQETGSDNEGANMGIATPSPNPLPNPDLTSDVYLN 2626 L ++ SH +D + R ++ +G+ A PN + T+ LN Sbjct: 3190 RSLELA---SSHSSDD----DESRTARSSGTHRSTAVSSTPAYLPNITEHVQATTPPELN 3242 Query: 2627 RHRLKPSILENVHDTYVASVDASRLP 2652 + P + +V+ A +S+LP Sbjct: 3243 VVQ-SPQLFPSVNKPVYAPRWSSQLP 3267 Score = 101 bits (241), Expect = 4e-19 Identities = 97/307 (31%), Positives = 132/307 (42%), Gaps = 40/307 (13%) Query: 2511 DGQLRHXXXXXXXXXXXASDMPAYLRGFDSSLHTRKDGERIASGSANSYLPNITEGAPLA 2570 D + R S PAYL + E S + P++ + P+ Sbjct: 3202 DDESRTARSSGTHRSTAVSSTPAYLPNITEHVQATTPPELNVVQSPQLF-PSVNK--PV- 3257 Query: 2571 MSPRWPSHVRED--QSRPEMGRWSQETGSDNEGAN-MGIATPSPNPLPNPDLTSDVYLNR 2627 +PRW S + + QS P +GRWSQ+TGSDNE + T SPNPLPNPDLT YL + Sbjct: 3258 YAPRWSSQLPDAYLQSPPNIGRWSQDTGSDNEHVHGQAKMTISPNPLPNPDLTDTSYLQQ 3317 Query: 2628 HRLK----PSILENVHDT---YVASVDASRLPLDNRYGVMEDELMYGVLPIDREKQMP-- 2678 H K PSILEN+ D Y S+ R ++YG + YG EK P Sbjct: 3318 HHNKINMPPSILENIRDAREGYEDSLYGRRGEYPDKYGSYKPPSHYG-----SEKDYPGG 3372 Query: 2679 YDPNYPISPTMYRLPGNPY-GSKTYLSSRTSDYGY----SPTKYMN----DTNVYGSRDF 2729 + I P Y Y RT GY S + Y++ ++YGS Sbjct: 3373 GSGSQTIGHMRSFHPDAAYLSDNIYDKQRTLGSGYLGAKSESPYLSKDRITPDIYGS--- 3429 Query: 2730 RDSGVSTRDHDGYPPRDFRDSGIATMLKNDY-QRKMDGHYGEYNDRMSEGSEKHHGHDKY 2788 RD S + Y + ++LKNDY Q++ DR+SEGS+K+ H Sbjct: 3430 RDGHYSLKRQPAYATDSLH--SVHSLLKNDYHQQQQQQQQHHLQDRLSEGSDKNGYH--- 3484 Query: 2789 LFPYTGK 2795 FPYT + Sbjct: 3485 -FPYTAE 3490 >UniRef50_Q7PPU8 Cluster: ENSANGP00000001238; n=2; Culicidae|Rep: ENSANGP00000001238 - Anopheles gambiae str. PEST Length = 3543 Score = 1495 bits (3706), Expect = 0.0 Identities = 727/1103 (65%), Positives = 870/1103 (78%), Gaps = 27/1103 (2%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 Q+NVLDCNDH+P FE +Q+ A+VREG S G+TV+T++ATDQDIGKNA++EY I + + Sbjct: 455 QVNVLDCNDHTPTFEAEQFHATVREGVSVGSTVITIRATDQDIGKNADIEYAITSILGEN 514 Query: 70 LNPEDAXXXXXXXXXXVQ-------DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122 V+ FRID RS + TR++LDRE YT++V ATD Sbjct: 515 QEQSGTAANGSNEGNPVEGDSNGSSQKFRIDARSCTISTRSALDREVSGMYTIMVTATDM 574 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 A+P S+R S+T T+ V I+DDNDNYPQFSE+TYTV V ED +N VIA I+A+DAD G Sbjct: 575 ATPQSERKSATTTVLVKILDDNDNYPQFSERTYTVQVREDQWANENNVIAHIQASDADQG 634 Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 N+AIRYAIIGGNTQ QFSIDS+SGDVSLVK LDYE VRSYRLVIRAQDGGSPSRSNTTQ Sbjct: 635 NNAAIRYAIIGGNTQSQFSIDSMSGDVSLVKPLDYENVRSYRLVIRAQDGGSPSRSNTTQ 694 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 LL+N+ D NDNAPRFYTS FQE+V E+VP+GY+IVRVQAYD+DEG N+E+TY++ ++D Sbjct: 695 LLVNVLDANDNAPRFYTSQFQEAVLESVPVGYNIVRVQAYDSDEGANSEITYSIQNRDD- 753 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 +P+ +DPR+GW++T+ LDRE Q++Y V A DGG PP+SA+ + Sbjct: 754 ---GMPLAVDPRTGWIHTTKALDREEQSRYSFQVVAVDGGIPPKSASTSVIVTIQDVNDN 810 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422 F P YE LAED+PPGTPV T+TATD DED+RLHYEIT GNTRGRF+ITSQNGRGL Sbjct: 811 DPTFSPKYYEAMLAEDQPPGTPVTTVTATDPDEDSRLHYEITAGNTRGRFAITSQNGRGL 870 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 IT+AQPLD+KQERR+ LT++ATDSG R+DTA+V INITDANN+APVFENAPY+ASVFEDA Sbjct: 871 ITIAQPLDYKQERRFALTITATDSGQRTDTAIVNINITDANNFAPVFENAPYSASVFEDA 930 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 PIGTTVLVVSA+DSDVGINAQITY L+ E N A+ + F IN QTGAI TN LDRE Sbjct: 931 PIGTTVLVVSASDSDVGINAQITYLLNDESVNGLGAN--EPFTINAQTGAIITNAKLDRE 988 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 + SGYLLTVTA+DGG PSLSDTTDVEISV DVNDN PVFK LY A I EDAL+GTSV Q Sbjct: 989 STSGYLLTVTAKDGGNPSLSDTTDVEISVTDVNDNAPVFKVPLYQATIPEDALIGTSVVQ 1048 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 + ATD D+GLNGR+ Y L KD +EGSFV+DP SGVIRTNK LDRES+ + L A+A D Sbjct: 1049 IAATDLDMGLNGRVKYALGQKDMDEGSFVVDPISGVIRTNKGLDRESIPVYHLTAIASDK 1108 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 GTP SS+V V I+++D+NDSPP F SD LT Y+ ENSP+G+ +GEI AHDPDEG NA+V Sbjct: 1109 GTPTMSSSVEVQIRLDDVNDSPPTFASDKLTLYVPENSPVGSVVGEIYAHDPDEGVNAIV 1168 Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEI 782 HYSI GGDDSNSFSL TR GSD+A+L+TM +LDYESPRK++EL+IRAASPPL NDV VEI Sbjct: 1169 HYSIIGGDDSNSFSLVTRPGSDRAQLLTMTELDYESPRKRFELIIRAASPPLRNDVYVEI 1228 Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILL 842 LVTDVNDNAPV++DFQ+IFNN++DCFP G GR+PA+DADVTDKL YRILSGNNANL+ L Sbjct: 1229 LVTDVNDNAPVLRDFQVIFNNFRDCFPSGVIGRIPAFDADVTDKLTYRILSGNNANLLRL 1288 Query: 843 NETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLND 902 N +TG +TLSPQLNTNVPK ATMEVSVTDG+NE KA+MQL VRLITE+ML NS+TVRL++ Sbjct: 1289 NSSTGGLTLSPQLNTNVPKFATMEVSVTDGINEAKAIMQLIVRLITEDMLFNSVTVRLDE 1348 Query: 903 MTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGV 962 MT E FLSPLL FF+DGLAAIIPCPKENI++FS+Q+D DV+G ILNVSFSARRPD Sbjct: 1349 MTEEAFLSPLLSFFLDGLAAIIPCPKENIFLFSIQEDIDVSGKILNVSFSARRPDVAF-- 1406 Query: 963 AGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNA 1022 +YS +L+ER+YL+R LARLATV+VLPFDDN+CV EPCLN+E+CL+VLKFGNA Sbjct: 1407 ----EEYYSSQYLQERIYLNRAILARLATVRVLPFDDNLCVREPCLNYEQCLSVLKFGNA 1462 Query: 1023 SGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVD-GDGSICRSGSQCVA 1081 SGF++SD+VLFRPI+PV +F C+CPEGFTG + E L EVD C++G C+ Sbjct: 1463 SGFIHSDTVLFRPIHPVNTFACKCPEGFTG-SREHYL--CDTEVDLCYSDPCQNGGSCM- 1518 Query: 1082 RREGGILCQGCSIDAAYTTAVCE 1104 RREGG C C+ YT CE Sbjct: 1519 RREGGYSCV-CT--EQYTGVNCE 1538 Score = 830 bits (2054), Expect = 0.0 Identities = 389/761 (51%), Positives = 504/761 (66%), Gaps = 44/761 (5%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 ++C C E +TGVNCET + + +C G C+ +GG YT Sbjct: 1524 YSCVCTEQYTGVNCETSIAGLKPCIS---EVCGDGYSCLTSGQGGHW-------PPYTKT 1573 Query: 1102 VCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVS 1161 CEL +RSF +SFLTFPG+++RHR +++LKFAT SGLLLYNGRYNE+HDF+ALE+++ Sbjct: 1574 -CELMSRSFTRNSFLTFPGMRQRHRFNIRLKFATVRDSGLLLYNGRYNEQHDFIALEIIN 1632 Query: 1162 SEAGRGGGPGLRFSFSLGGGKSEITV--EGNVGDGSWHTVEIEYFNRTITMILDDCDKVL 1219 + + FSFSLG +T+ + V DG+WHTVE++YFNRT+ + LD+CD Sbjct: 1633 GK--------VVFSFSLGDKVETVTINQQRKVSDGNWHTVEVKYFNRTVLLSLDNCDTAT 1684 Query: 1220 SLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNK 1279 +LAG G ++ CAN T VL RC E CHRF DLTGPLQIGGLP IP+ FQ+++ Sbjct: 1685 ALAG---LGERWNCANQTTLVLDRRCASLVEPCHRFFDLTGPLQIGGLPKIPAYFQIRSH 1741 Query: 1280 DFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLW-DTYICD 1338 FVGCISD YID +++DL +Y+ADNGT+AGCP+K + C+S PC+NG C + W + + CD Sbjct: 1742 SFVGCISDLYIDQRYVDLGAYIADNGTVAGCPQKAASCASEPCFNGGTCREGWGEGWECD 1801 Query: 1339 CKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMSIQ-- 1396 C +G TG C +S PWRF GDG+LSFNPLLRPIQLPWL A S+RTR+RD+FVM IQ Sbjct: 1802 CPDGFTGNACQESVALPWRFHGDGILSFNPLLRPIQLPWLTAFSLRTRKRDSFVMEIQVG 1861 Query: 1397 --------LKSGLLHYSYNGETMYLPMATLSDGAWHRIEIKWLGTDISVTVDYGLRTVLM 1448 L+ G+L Y YNGE + L A L+DG WHR+EIKW+GT++S+TVDYG R+ ++ Sbjct: 1862 QNSSAVVSLRDGILQYLYNGEPLQLAGADLADGRWHRVEIKWMGTEVSLTVDYGQRSGVL 1921 Query: 1449 PMLANKIQGQYIGKILIGGLDTTAGL-LASDVGFFEGCIQDVRIGTAQSLLNRPTVRENV 1507 P + KIQG Y+G+I+IGGL+ T G FEGCIQDVR+G QS+L RPTVRENV Sbjct: 1922 P-VTQKIQGLYVGRIVIGGLEGTIGQHYGGPSENFEGCIQDVRVGGVQSVLKRPTVRENV 1980 Query: 1508 RDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPCG-AARCVPDQ 1566 DGC S A C CP S CV++WD + C C G VG +C C + PC C D Sbjct: 1981 LDGCASNAKCPEG-CPEESVCVSNWDEAYCECLHGFVGGECKPVCTVKPCSDNGICRADT 2039 Query: 1567 -TPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGK 1625 KGY C C + + C + ++ CP GWWG +CGPC C+V +GYHP+C+K G+ Sbjct: 2040 VNTKGYRCECNSSLS-SGEYCENTVQQPCPAGWWGERSCGPCKCNVKQGYHPNCDKSTGQ 2098 Query: 1626 CHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVT 1685 C+C+ENHY+P CLPC+CY GS SC ++GQC CR GVIGR CD+C+N YAEVT Sbjct: 2099 CYCRENHYQPVNDTVCLPCECYTVGSYGKSCN-SSGQCECREGVIGRRCDSCSNPYAEVT 2157 Query: 1686 PNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSGRATRTCDETKDVPWQDPDM 1745 N GCEVVYDGCP+S + G+WWPRT FG + +CP + G+ TR CD+ + W PDM Sbjct: 2158 LN-GCEVVYDGCPKSHSAGLWWPRTAFGELAVENCPAPARGKGTRRCDQVQS-GWGAPDM 2215 Query: 1746 FNCTTATFYQLRKQLHKIETGELTMNTFVGVRVAADLSTAC 1786 FNCT+ F LRKQL +IE L +NTF+ V+VAA L AC Sbjct: 2216 FNCTSEAFLDLRKQLSQIEVDGLELNTFISVKVAASLQQAC 2256 Score = 331 bits (813), Expect = 2e-88 Identities = 232/689 (33%), Positives = 346/689 (50%), Gaps = 62/689 (8%) Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 P F + Y SV E+ N + ++A D + +++ +Q F +DS +G Sbjct: 361 PYFEQALYVASVLEEQPPGAN--VITVRARDPEDSPVVYSLVSLLDSRSQAMFKVDSRTG 418 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 V+ TLD E + + + A D P RS TT L +N+ D ND+ P F F +V Sbjct: 419 VVTTSSTLDRELMDVHYFRVIATDDSFPPRSGTTTLQVNVLDCNDHTPTFEAEQFHATVR 478 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMT-----DKDYTG------NVDLPI------- 309 E V +G +++ ++A D D G NA++ Y +T +++ +G N P+ Sbjct: 479 EGVSVGSTVITIRATDQDIGKNADIEYAITSILGENQEQSGTAANGSNEGNPVEGDSNGS 538 Query: 310 ----TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP---RSATATXXXXXXXXXXX 362 ID RS + T LDRE Y ++VTATD P +SAT T Sbjct: 539 SQKFRIDARSCTISTRSALDREVSGMYTIMVTATDMATPQSERKSATTTVLVKILDDNDN 598 Query: 363 XXXFMPGQYEVELAEDE--PPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQN 418 F Y V++ ED+ + + A+DAD+ N + Y I GGNT+ +FSI S + Sbjct: 599 YPQFSERTYTVQVREDQWANENNVIAHIQASDADQGNNAAIRYAIIGGNTQSQFSIDSMS 658 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTA 476 G +++ +PLD++ R Y L + A D G RS+T + +N+ DAN+ AP F + + Sbjct: 659 GD--VSLVKPLDYENVRSYRLVIRAQDGGSPSRSNTTQLLVNVLDANDNAPRFYTSQFQE 716 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 +V E P+G ++ V A DSD G N++ITYS+ + +A ++P+TG I T Sbjct: 717 AVLESVPVGYNIVRVQAYDSDEGANSEITYSIQNRDDGMPLA-------VDPRTGWIHTT 769 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 K LDRE S Y V A DGG+P S +T V +++ DVNDN+P F + Y A + ED Sbjct: 770 KALDREEQSRYSFQVVAVDGGIPPKSASTSVIVTIQDVNDNDPTFSPKYYEAMLAEDQPP 829 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS--GVIRTNKALDRESVATHD 654 GT V+ V ATD D + R+HYE+ G F I + G+I + LD + Sbjct: 830 GTPVTTVTATDPDE--DSRLHYEI-TAGNTRGRFAITSQNGRGLITIAQPLDYKQERRFA 886 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 L A D G ++ T IV+I I D N+ PVFE+ + + E++PIGTT+ + A D Sbjct: 887 LTITATDSG--QRTDTAIVNINITDANNFAPVFENAPYSASVFEDAPIGTTVLVVSASDS 944 Query: 715 DEGPNAVVHY-----SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 D G NA + Y S+ G + F++ + G+ ++T LD ES Y L + A Sbjct: 945 DVGINAQITYLLNDESVNGLGANEPFTINAQTGA----IITNAKLDRES-TSGYLLTVTA 999 Query: 770 ---ASPPLWNDVRVEILVTDVNDNAPVMK 795 +P L + VEI VTDVNDNAPV K Sbjct: 1000 KDGGNPSLSDTTDVEISVTDVNDNAPVFK 1028 Score = 328 bits (806), Expect = 1e-87 Identities = 271/877 (30%), Positives = 410/877 (46%), Gaps = 85/877 (9%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 + + SP FE Y ASV E G V+T++A D + ++ V Y++ L+ Sbjct: 355 ELRNQSPYFEQALYVASVLEEQPPGANVITVRARDPE---DSPVVYSL----VSLLDSRS 407 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134 Q +F++D R+G + T ++LDRE + + V ATD + P S T Sbjct: 408 ------------QAMFKVDSRTGVVTTSSTLDRELMDVHYFRVIATDDSFPPR---SGTT 452 Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA---I 191 T+ VN++D ND+ P F + + +V E +SV + I+ATD D+G N+ I YA I Sbjct: 453 TLQVNVLDCNDHTPTFEAEQFHATVREGVSV--GSTVITIRATDQDIGKNADIEYAITSI 510 Query: 192 IGGN-----------------------TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIR 228 +G N + +F ID+ S +S LD E Y +++ Sbjct: 511 LGENQEQSGTAANGSNEGNPVEGDSNGSSQKFRIDARSCTISTRSALDREVSGMYTIMVT 570 Query: 229 AQDGGSPS---RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS--IVRVQAYD 283 A D +P +S TT +L+ I D NDN P+F + V E+ + I +QA D Sbjct: 571 ATDMATPQSERKSATTTVLVKILDDNDNYPQFSERTYTVQVREDQWANENNVIAHIQASD 630 Query: 284 ADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD 343 AD+G NA + Y + GN +ID SG V LD E Y+L++ A DGG Sbjct: 631 ADQGNNAAIRYAIIG----GNTQSQFSIDSMSGDVSLVKPLDYENVRSYRLVIRAQDGGS 686 Query: 344 PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEI 403 P RS T F Q++ + E P G +V + A D+DE Sbjct: 687 PSRSNTTQLLVNVLDANDNAPRFYTSQFQEAVLESVPVGYNIVRVQAYDSDEGANSEITY 746 Query: 404 TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITD 461 + N + G I + LD +++ RY V A D G +S + V + I D Sbjct: 747 SIQNRDDGMPLAVDPRTGWIHTTKALDREEQSRYSFQVVAVDGGIPPKSASTSVIVTIQD 806 Query: 462 ANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521 N+ P F Y A + ED P GT V V+ATD D ++++ Y +++ + A Sbjct: 807 VNDNDPTFSPKYYEAMLAEDQPPGTPVTTVTATDPDE--DSRLHYEITAGNTRGRFAITS 864 Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581 Q G IT + LD + + LT+TA D G +DT V I++ D N+ PVF Sbjct: 865 QN-----GRGLITIAQPLDYKQERRFALTITATDSG--QRTDTAIVNINITDANNFAPVF 917 Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD----REEGSFVIDPASG 637 + Y+A++ EDA +GT+V V A+D+DVG+N +I Y L+ + F I+ +G Sbjct: 918 ENAPYSASVFEDAPIGTTVLVVSASDSDVGINAQITYLLNDESVNGLGANEPFTINAQTG 977 Query: 638 VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697 I TN LDRES + + L A DGG P S T V I + D+ND+ PVF+ I Sbjct: 978 AIITNAKLDRESTSGYLLTVTAKDGGNPSLSDTTDVEISVTDVNDNAPVFKVPLYQATIP 1037 Query: 698 ENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD-DSNSFSLETRQGSDKAELVTMVDLDY 756 E++ IGT++ +I A D D G N V Y++ D D SF ++ G + T LD Sbjct: 1038 EDALIGTSVVQIAATDLDMGLNGRVKYALGQKDMDEGSFVVDPISG----VIRTNKGLDR 1093 Query: 757 ESPRKKYELVIRA--ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-F 813 ES + I + +P + + V V+I + DVND+ P ++ + PVG Sbjct: 1094 ESIPVYHLTAIASDKGTPTMSSSVEVQIRLDDVNDSPPTFASDKLTL-YVPENSPVGSVV 1152 Query: 814 GRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGS 848 G + A+D D V + Y I+ G+++N L GS Sbjct: 1153 GEIYAHDPDEGVNAIVHYSIIGGDDSNSFSLVTRPGS 1189 Score = 253 bits (619), Expect = 6e-65 Identities = 200/671 (29%), Positives = 316/671 (47%), Gaps = 64/671 (9%) Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 R++ + +P F +L+ SV E P G +++ V+A D ++ + + Y++ Sbjct: 354 RELRNQSPYFEQALYVASVLEEQPPGANVITVRARDPED---SPVVYSLVSL-LDSRSQA 409 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 +D R+G V TS LDRE + V ATD PPRS T T F Sbjct: 410 MFKVDSRTGVVTTSSTLDRELMDVHYFRVIATDDSFPPRSGTTTLQVNVLDCNDHTPTFE 469 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEIT--------------GGNTRGR 411 Q+ + E G+ V+T+ ATD D ++ + Y IT G+ G Sbjct: 470 AEQFHATVREGVSVGSTVITIRATDQDIGKNADIEYAITSILGENQEQSGTAANGSNEGN 529 Query: 412 FSITSQNGRG----------LITVAQPLDFKQERRYVLTVSATD-----SGGRSDTAMVQ 456 NG I+ LD + Y + V+ATD S +S T V Sbjct: 530 PVEGDSNGSSQKFRIDARSCTISTRSALDREVSGMYTIMVTATDMATPQSERKSATTTVL 589 Query: 457 INITDANNYAPVFENAPYTASVFED--APIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 + I D N+ P F YT V ED A + + A+D+D G NA I Y++ Sbjct: 590 VKILDDNDNYPQFSERTYTVQVREDQWANENNVIAHIQASDADQGNNAAIRYAIIG---- 645 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 + QF I+ +G ++ K LD E + Y L + A+DGG PS S+TT + ++V+D Sbjct: 646 ---GNTQSQFSIDSMSGDVSLVKPLDYENVRSYRLVIRAQDGGSPSRSNTTQLLVNVLDA 702 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG-SFVID 633 NDN P F + ++E VG ++ +V A D+D G N I Y + ++R++G +D Sbjct: 703 NDNAPRFYTSQFQEAVLESVPVGYNIVRVQAYDSDEGANSEITYSI--QNRDDGMPLAVD 760 Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693 P +G I T KALDRE + + + VA+DGG PP+S++ V + I+D+ND+ P F Sbjct: 761 PRTGWIHTTKALDREEQSRYSFQVVAVDGGIPPKSASTSVIVTIQDVNDNDPTFSPKYYE 820 Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753 ++E+ P GT + + A DPDE ++ +HY I G+ F++ ++ G L+T+ Sbjct: 821 AMLAEDQPPGTPVTTVTATDPDE--DSRLHYEITAGNTRGRFAITSQNGRG---LITIAQ 875 Query: 754 -LDYESPRKKYELVIRAASPPLWNDVR-VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811 LDY+ R ++ L I A D V I +TD N+ APV ++ + ++D P+G Sbjct: 876 PLDYKQER-RFALTITATDSGQRTDTAIVNINITDANNFAPVFENAPYSASVFEDA-PIG 933 Query: 812 PFGR-VPAYDADV------TDKLQYRILSGNNAN-LILLNETTGSMTLSPQLNTNVPKLA 863 V A D+DV T L ++G AN +N TG++ + +L+ Sbjct: 934 TTVLVVSASDSDVGINAQITYLLNDESVNGLGANEPFTINAQTGAIITNAKLDRESTSGY 993 Query: 864 TMEVSVTDGVN 874 + V+ DG N Sbjct: 994 LLTVTAKDGGN 1004 Score = 229 bits (560), Expect = 8e-58 Identities = 119/273 (43%), Positives = 179/273 (65%), Gaps = 28/273 (10%) Query: 1791 RLYGADVVVAEGILLELMDYELRQAGLNLTHSQDKDYVRNLLKSTNTILNVEYEREWKRI 1850 +LYGAD+++ + +L ELM YE Q GLNL+HSQDK YVRNL++S IL+ Y EWKR+ Sbjct: 2317 KLYGADLLITDRLLHELMRYEAYQHGLNLSHSQDKHYVRNLVESAGEILDRRYASEWKRV 2376 Query: 1851 RELTGHGAELLVQKFDEYIAVLAESQHDTYTSPFEIVTKDVVISVDTVTSESIYGFEPTQ 1910 ++LTG G + LV F++Y+ VLA SQHDTYT+PFEIV K++V+ +D VT+ES++G+E Sbjct: 2377 QDLTGRGPDDLVDAFNQYMIVLARSQHDTYTNPFEIVHKNMVLGMDIVTTESLFGYESQM 2436 Query: 1911 LNRL---------NVDSYTTERVVALPDTSAFI-HSPIQAXXXXXXXXXXXXXXXXXXXV 1960 + + ++ + E V+ LPDTS+F+ +SP Q + Sbjct: 2437 VKQQQFKQAKGHPDLHGHPAETVI-LPDTSSFLQNSPKQ----------------KQPLI 2479 Query: 1961 SFPKYNNYVRSKNKFDKYTRVLLPLDLLGISNNNLQDITDTNYETRAVFGYVQYSRNSSQ 2020 SFPKYNNY++ ++KFD+ T+VL+PLD+LGI+ + ++ + E RA+F Y QY +++ + Sbjct: 2480 SFPKYNNYIQDRSKFDRSTKVLVPLDMLGITAPDKNEVVNQIAEHRAIFTYAQY-KDAGE 2538 Query: 2021 LMPLRMDDSVSLRWGVNITIGSPILQIAVFVPE 2053 L P D++V+ RWGV + I S +L IA+ PE Sbjct: 2539 LFPTNFDETVTRRWGVEMQIASSVLSIAIVTPE 2571 Score = 182 bits (442), Expect = 2e-43 Identities = 142/459 (30%), Positives = 218/459 (47%), Gaps = 49/459 (10%) Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509 +DT + + + N +P FE A Y ASV E+ P G V+ V A D + ++ + YSL Sbjct: 344 NDTDIAKRVRRELRNQSPYFEQALYVASVLEEQPPGANVITVRARDPE---DSPVVYSLV 400 Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569 S + + + A F ++ +TG +TT+ LDRE M + V A D P S TT +++ Sbjct: 401 SLLDSRSQA----MFKVDSRTGVVTTSSTLDRELMDVHYFRVIATDDSFPPRSGTTTLQV 456 Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE----LDPKDR 625 +V+D ND+ P F+ + + A + E VG++V + ATD D+G N I Y L Sbjct: 457 NVLDCNDHTPTFEAEQFHATVREGVSVGSTVITIRATDQDIGKNADIEYAITSILGENQE 516 Query: 626 EEGS---------------------FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 + G+ F ID S I T ALDRE + + A D T Sbjct: 517 QSGTAANGSNEGNPVEGDSNGSSQKFRIDARSCTISTRSALDREVSGMYTIMVTATDMAT 576 Query: 665 PP---QSSTVIVHIKIEDINDSPPVFESDCLTFYISEN--SPIGTTIGEIRAHDPDEGPN 719 P +S+T V +KI D ND+ P F T + E+ + I I+A D D+G N Sbjct: 577 PQSERKSATTTVLVKILDDNDNYPQFSERTYTVQVREDQWANENNVIAHIQASDADQGNN 636 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776 A + Y+I GG+ + FS+++ G ++ + LDYE+ R Y LVIRA SP N Sbjct: 637 AAIRYAIIGGNTQSQFSIDSMSG----DVSLVKPLDYENVR-SYRLVIRAQDGGSPSRSN 691 Query: 777 DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILS 833 ++ + V D NDNAP Q + PVG RV AYD+D ++ Y I + Sbjct: 692 TTQLLVNVLDANDNAPRFYTSQ-FQEAVLESVPVGYNIVRVQAYDSDEGANSEITYSIQN 750 Query: 834 GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 ++ + ++ TG + + L+ + +V DG Sbjct: 751 RDDGMPLAVDPRTGWIHTTKALDREEQSRYSFQVVAVDG 789 Score = 166 bits (404), Expect = 7e-39 Identities = 87/189 (46%), Positives = 128/189 (67%), Gaps = 13/189 (6%) Query: 2143 DGPKVMALVMDGETRSNATGVGKKMYRSLSGIRLKKPIRLQIWLDINRETFGSRTNPQCV 2202 DG ++ MD +R+N +G+ LK+ I+LQ+WL+I R F SR+NPQCV Sbjct: 2696 DGGIPESVEMDSASRTNYVPLGQP--------HLKQAIKLQMWLNIPRNRFVSRSNPQCV 2747 Query: 2203 HWSTLRGSGEWSRVGCHTEI-DYDWSPYSEEPLLINCTCNHLSTFAVLVDEVDVEFIPEP 2261 W+T + W+R+GC TEI +Y+ +++ +++NCTCN L+T+AVLVD +D E IPEP Sbjct: 2748 RWNT--HANLWTRIGCQTEIPNYEMIGHNDT-IVVNCTCNQLATYAVLVDIIDPEDIPEP 2804 Query: 2262 SLLESVTSYTAFSISLPLLLTSWAALCLIRGGAATVSNSIHKHLIFSVFMAELLYLIALK 2321 SLL +TSY+AF +SLP+L +L L+R G T SNSIH++L+F +F AELL+ +A++ Sbjct: 2805 SLLVQITSYSAFLLSLPILFAVIVSLALLR-GLQTNSNSIHQNLLFCIFTAELLFFVAIQ 2863 Query: 2322 ARTSLVQNE 2330 AR L+ NE Sbjct: 2864 ARRDLLDNE 2872 Score = 120 bits (289), Expect = 6e-25 Identities = 73/232 (31%), Positives = 102/232 (43%), Gaps = 8/232 (3%) Query: 2330 EPVVWWVVIPXXXXXXXXXXXXXXXXXXXFTVRDHVTGFGNLRMLLAVSIVCLPLLCVAW 2389 E V+WW+V P FT++DHV GFGNLR LL +S+V LPLL + W Sbjct: 2953 ESVIWWMVGPIAIVSVFDLFILFLSVKAAFTIKDHVLGFGNLRTLLWLSVVSLPLLGIMW 3012 Query: 2390 ASALLLGSEAGGRRXXXXXXXXXXXXXXXIAASLGYIAFNVRVRDNLKRTVLRCMGKKVP 2449 A+L SE + + +GY N RVR+NL LRCMG+KVP Sbjct: 3013 VLAVLSASE---NSQLLNMLLSAVVIMHSLFSIIGYCIINKRVRENLHNAFLRCMGRKVP 3069 Query: 2450 LADTSVIISSSAHNLSQVNRSSLAYHSSTEPGRQMRNIGIXXXXXXXXXXXXXXXXXXXX 2509 L ++S+ IS+S+ N+ A S + RNIGI Sbjct: 3070 LLESSIAISNSSQNVGSPKTPGFAGSSGGQYDTARRNIGI-STSSTTSRSTAKTSSSPYR 3128 Query: 2510 XDGQLRHXXXXXXXXXXXASDMPAYLRGF--DSSLHTRKDGERIASGSANSY 2559 DGQ RH + + +Y+RG +S+L K+G + G S+ Sbjct: 3129 SDGQFRH--TSTSTSNYNSDGVASYMRGHYEESALRKIKNGGQGRDGERRSH 3178 Score = 95.9 bits (228), Expect = 1e-17 Identities = 53/168 (31%), Positives = 87/168 (51%), Gaps = 5/168 (2%) Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620 L+DT + ++ + P F+Q LY A+++E+ G +V V A D + + + Y L Sbjct: 343 LNDTDIAKRVRRELRNQSPYFEQALYVASVLEEQPPGANVITVRARDPE---DSPVVYSL 399 Query: 621 DP--KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678 R + F +D +GV+ T+ LDRE + H + +A D PP+S T + + + Sbjct: 400 VSLLDSRSQAMFKVDSRTGVVTTSSTLDRELMDVHYFRVIATDDSFPPRSGTTTLQVNVL 459 Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 D ND P FE++ + E +G+T+ IRA D D G NA + Y+I Sbjct: 460 DCNDHTPTFEAEQFHATVREGVSVGSTVITIRATDQDIGKNADIEYAI 507 Score = 91.5 bits (217), Expect = 3e-16 Identities = 83/265 (31%), Positives = 113/265 (42%), Gaps = 33/265 (12%) Query: 2556 ANSYLPNITEGAP-------LAMSP---------RWPSHVREDQSRPEMGRWSQETGSDN 2599 + SYLPNITE + SP RWP+ + P GRWSQET SDN Sbjct: 3225 STSYLPNITEHVATTPPELHVVQSPQLFPNVTPTRWPNQNANNYMPPGNGRWSQETASDN 3284 Query: 2600 EGANMGIATPSPNPLPNPDLTSDVYL--NRHRLKPSILENVHDTYVASVDASRLPLDNRY 2657 E A+ + + LPNPD+T YL NR + PSILEN+ + Y + L D Y Sbjct: 3285 E-AHPHKSPTNGGSLPNPDITETSYLHQNRMNMPPSILENIQENYNIGYSNTDLHSDRNY 3343 Query: 2658 GVMEDELMYGVLPIDREKQMPYDPNYPISPTMYRLPGNPYGSKTYLSSRTSDYGYSPTKY 2717 + Y V P D K+ Y+ NPY K L R+ GY + Sbjct: 3344 SNYGNADNY-VPPADYAKRHTGSMQVINHMRAYQ-HENPYALKESLYERSRTLGYGTSAG 3401 Query: 2718 MNDTNVYGSRDFRDSGVSTRDHDGYPPRDFRDSGIATMLKNDYQRKMDGHY-------GE 2770 ++ + F+ S + ++LKNDYQ++ Y G Sbjct: 3402 GAESPYHAGHPLTAPNDLYSPPGAIHGMSFK-SSVQSLLKNDYQQQQRQQYKHHQTGNGG 3460 Query: 2771 YNDRMSEGSEKHHGHDKYLFPYTGK 2795 +DRMSEGS+K + Y FPYT + Sbjct: 3461 ESDRMSEGSDK----NPYNFPYTAE 3481 Score = 42.7 bits (96), Expect = 0.14 Identities = 37/160 (23%), Positives = 62/160 (38%), Gaps = 7/160 (4%) Query: 638 VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697 +I N DR+ + D + + + + ++ E N SP FE + Sbjct: 315 IITYNVRCDRKDIIDADHRLKIVYHHQELNDTDIAKRVRRELRNQSP-YFEQALYVASVL 373 Query: 698 ENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757 E P G + +RA DP++ P S+ F +++R G + T LD E Sbjct: 374 EEQPPGANVITVRARDPEDSPVVYSLVSLLDSRSQAMFKVDSRTG----VVTTSSTLDRE 429 Query: 758 SPRKKYELVIRA--ASPPLWNDVRVEILVTDVNDNAPVMK 795 Y VI + PP +++ V D ND+ P + Sbjct: 430 LMDVHYFRVIATDDSFPPRSGTTTLQVNVLDCNDHTPTFE 469 Score = 37.1 bits (82), Expect = 7.0 Identities = 16/42 (38%), Positives = 19/42 (45%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADS 1351 C + C S PC NG C Y C C E +TG +C S Sbjct: 1499 CDTEVDLCYSDPCQNGGSCMRREGGYSCVCTEQYTGVNCETS 1540 >UniRef50_UPI0000DB794E Cluster: PREDICTED: similar to Protocadherin-like wing polarity protein stan precursor (Protein starry night) (Protein flamingo); n=2; Apocrita|Rep: PREDICTED: similar to Protocadherin-like wing polarity protein stan precursor (Protein starry night) (Protein flamingo) - Apis mellifera Length = 3166 Score = 1433 bits (3550), Expect = 0.0 Identities = 700/1088 (64%), Positives = 856/1088 (78%), Gaps = 31/1088 (2%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD- 68 Q+NVLD NDH+P FE + EAS+REG G+TV+T+KATDQD G+NAEVEY+I T+ Sbjct: 353 QVNVLDTNDHAPSFEWPEEEASIREGVPVGSTVVTVKATDQDAGRNAEVEYSILSTTSSS 412 Query: 69 -TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 T N EDA +FRID R+G + TR LDREK YTV++ +DQA+P S Sbjct: 413 GTANTEDAL------------IFRIDPRTGVVTTRTPLDREKTEVYTVILSVSDQATPPS 460 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 R ++ AT+ V ++DDNDNYPQF+E+TY+ + ED+ T NPVIA+I+ATDAD G N+A+ Sbjct: 461 ARKTANATLVVRVLDDNDNYPQFTERTYSAWIPEDLDYTANPVIARIRATDADSGNNAAV 520 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 RYAIIGGNTQ FSIDS+ GDV+LVK LDYE RSY++VIRAQDGGSP+RSNTTQLL+++ Sbjct: 521 RYAIIGGNTQNTFSIDSMVGDVALVKPLDYESTRSYKIVIRAQDGGSPARSNTTQLLVHV 580 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG--NV 305 DVNDNAPRFYTS FQESVSENVP+GYSI+R+QAYDADEG NA++ YT+ +D+TG Sbjct: 581 GDVNDNAPRFYTSHFQESVSENVPVGYSILRIQAYDADEGANAQIKYTIGARDFTGASTE 640 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 + PIT++ +GW+YT+ QLDRE ++YQ V A D G+ +SA+AT Sbjct: 641 NFPITVNTETGWLYTTKQLDREQCSRYQFTVIAADSGEISKSASATVILTVTDVNDNDPY 700 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV 425 F P YE ++ED+PPGTPV ++TATD DED R+HYEIT GNTRGRF+I SQNGRGLIT+ Sbjct: 701 FDPKNYESVVSEDDPPGTPVTSVTATDPDEDARIHYEITAGNTRGRFAIASQNGRGLITI 760 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 AQPLD+KQE+R+VLTV+A+DSGGR+DTA+V +NI+DANN++PVFENAPY+ SVFEDAPIG Sbjct: 761 AQPLDYKQEKRFVLTVTASDSGGRTDTALVYVNISDANNFSPVFENAPYSVSVFEDAPIG 820 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 TTVLVVSATDSDVG NAQ+TYSL ++ ++ + +F+INPQTGAITT K LDRE + Sbjct: 821 TTVLVVSATDSDVGKNAQVTYSLDTDNGDQTAS----EFIINPQTGAITTTKPLDREIVP 876 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 YLLTVTARDGG+P LSDTTDVEISV DVNDN PVF+ Y +I ED LVGTSV +V A Sbjct: 877 AYLLTVTARDGGIPPLSDTTDVEISVTDVNDNAPVFEAPQYQGSIPEDVLVGTSVLRVSA 936 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 TDAD LNGR+ Y L+ D +G+F +D +G+IRT K LDRESVA + LKAVA+D G+P Sbjct: 937 TDADTDLNGRVRYALE--DDGDGAFAVDSTTGIIRTAKPLDRESVAKYILKAVAMDRGSP 994 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 S+ V V IKIED+NDSPP FE+D + YI+ENSPIG+T+GEI AHDPDEGPNAVV YS Sbjct: 995 SLSTVVPVTIKIEDVNDSPPAFENDKIILYIAENSPIGSTVGEIYAHDPDEGPNAVVQYS 1054 Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVT 785 + GG+DSNSF+L R G+D+AEL+T+ +LDYESP+KK+ELV+RAASPPL +D V+ILVT Sbjct: 1055 VIGGEDSNSFALNIRPGADRAELITLEELDYESPKKKFELVVRAASPPLRSDALVQILVT 1114 Query: 786 DVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNET 845 DVNDNAPV+KDFQIIFNN+KD FP P G++PA DADVTDKL Y IL+GNNANLI LN T Sbjct: 1115 DVNDNAPVLKDFQIIFNNFKDFFPTAPIGKIPAIDADVTDKLTYTILAGNNANLIDLNRT 1174 Query: 846 TGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTA 905 +G + LSPQLNTNVP++ATMEVSVTDG+NE+KA M LSVRLIT++MLLNSITVRL+DMTA Sbjct: 1175 SGEIRLSPQLNTNVPRVATMEVSVTDGINEVKATMTLSVRLITDKMLLNSITVRLDDMTA 1234 Query: 906 EQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGD 965 E FLSPLLG+F+DGLAAIIPCP+ENI++FS+Q+D +V G ILNVSFSAR+ E GV + Sbjct: 1235 EAFLSPLLGYFLDGLAAIIPCPRENIFLFSIQEDANVNGKILNVSFSARK--VEPGVTDE 1292 Query: 966 PSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGF 1025 YSP L+ERVYL+R LARLATV VLPFDDN+CV EPCLNFEECLTVLKFGNASGF Sbjct: 1293 ---FYSPQFLQERVYLNRGILARLATVTVLPFDDNLCVREPCLNFEECLTVLKFGNASGF 1349 Query: 1026 VNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG 1085 +SD+VLFRPIYPVT+F C+C GFTG + E+ L + C +G C RREG Sbjct: 1350 ASSDTVLFRPIYPVTTFACRCARGFTG-SKESYLCDTEVNLCYSNP-CVNGGTCY-RREG 1406 Query: 1086 GILCQGCS 1093 G C CS Sbjct: 1407 GYAC-SCS 1413 Score = 1054 bits (2609), Expect = 0.0 Identities = 497/1035 (48%), Positives = 665/1035 (64%), Gaps = 60/1035 (5%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYT-T 1100 + C C F G NCE L K SC IC+ GSQC + GG C+GC + T Sbjct: 1408 YACSCSPEFGGENCEISLDKNSCAP----GICKGGSQCTMKTTGGFTCEGCPVTTLENVT 1463 Query: 1101 AVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELV 1160 +CEL+ARSF ++FLTF L++RHR+ +KL+FAT+ +GLLLYNGRYNE+HDF+ALE++ Sbjct: 1464 PLCELKARSFGPATFLTFASLRQRHRLQIKLRFATEAANGLLLYNGRYNEKHDFIALEII 1523 Query: 1161 SSEAGRGGGPGLRFSFSLGGG--KSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKV 1218 SE ++FSFSLG ++ ++ G V DG WH VE+ Y N+T+T+ LD+CD Sbjct: 1524 DSE--------VQFSFSLGDEITRTSASIPGGVSDGQWHEVEVSYINKTVTISLDNCDVA 1575 Query: 1219 LSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKN 1278 L+L G K++CA + +VL RC I TETCHRFLDLTGPLQ+GGLP IPSSF+++N Sbjct: 1576 LALEYGDRLGRKWSCAGRSEQVLEERCSIVTETCHRFLDLTGPLQLGGLPAIPSSFRIRN 1635 Query: 1279 KDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICD 1338 KDFVGC+SD YIDH FIDLNS+VADNGT GCPEK S CSS+PC N +C ++W ++C+ Sbjct: 1636 KDFVGCVSDLYIDHIFIDLNSFVADNGTNPGCPEKVSFCSSSPCKNNGKCREIWAGFVCE 1695 Query: 1339 CKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMS---- 1394 C+E G CAD G PW F GDGM+SFNPLLRPIQLPWL ALS+RTR R AFVMS Sbjct: 1696 CEENFAGPTCADEVGKPWNFHGDGMISFNPLLRPIQLPWLTALSLRTRSRQAFVMSVQIG 1755 Query: 1395 ------IQLKSGLLHYSYNGETMYLPMATLSDGAWHRIEIKWLGTDISVTVDYGLRTVLM 1448 IQ++ G L +G + + ++DG WHR+EI W +S+ +DY R +L Sbjct: 1756 QNSSALIQIREGKLVALLDGADIIQTLNDIADGEWHRVEIVWQSGHVSLDIDYRSRPILS 1815 Query: 1449 PMLANKIQGQYIGKILIGGLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRPTVRENVR 1508 + A K+QG YIG+IL+GG + + + ++ +F+GC+QD+RIG+ QS+L RPTV+ENV Sbjct: 1816 SLPA-KLQGLYIGRILVGGPEQSMNI---ELPYFDGCLQDIRIGSNQSVLLRPTVQENVA 1871 Query: 1509 DGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPC-GAARCVPDQT 1567 GC S A+C + CP S CV W + C C GRVG C C+L PC + C+ D T Sbjct: 1872 TGCSSEAECNVD-CPEASICVPKWKAGECVCATGRVGRNCERVCDLNPCNNSGACIEDAT 1930 Query: 1568 P-KGYSCAC-EPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGK 1625 +GY C C P Y + + C + CP WWG CGPC CD ++GY P CNK G+ Sbjct: 1931 SRRGYRCECNSPEY--SGNYCEIKADQPCPATWWGSPVCGPCHCDESKGYDPACNKTTGE 1988 Query: 1626 CHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVT 1685 C+CKENHY+P G EC+PC+CYA GS C+ TGQC CR GVIGR+C AC N YAEVT Sbjct: 1989 CYCKENHYQPSGKKECIPCECYATGSFGPRCDTETGQCRCRVGVIGRSCTACPNPYAEVT 2048 Query: 1686 PNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSGRATRTCDETKDVPWQDPDM 1745 GCEVVYDGCPRS++ G+WWPRTKFG+ + DCP + G+ +R+CD+ K WQ+PD+ Sbjct: 2049 LR-GCEVVYDGCPRSYSEGLWWPRTKFGMIAVEDCPDMAEGKTSRSCDD-KLGGWQEPDL 2106 Query: 1746 FNCTTATFYQLRKQLHKIETGELTMNTFVGVRVAADLSTACANTPRLYGADVVVAEGILL 1805 FNCT+ F + R QL +ET ELT+NT+V V++A D+ A T LYGAD++VAE +L+ Sbjct: 2107 FNCTSEAFIEQRHQLAALETKELTLNTYVAVKIAKDVYRAVNVTKELYGADLLVAESLLV 2166 Query: 1806 ELMDYELRQAGLNLTHSQDKDYVRNLLKSTNTILNVEYEREWKRIRELTGHGAELLVQKF 1865 L+ YE GLNLTHSQDKDYV L+ + IL +Y +W RI L G + ++ Sbjct: 2167 ALLQYEESLVGLNLTHSQDKDYVSYLVGIASNILKSKYLEKWSRIETLNGDTPDKVLNAM 2226 Query: 1866 DEYIAVLAESQHDTYTSPFEIVTKDVVISVDTVTSESIYGFEPTQL----NRLNVDSYTT 1921 Y+ L SQHDT+T+PFEIV +VV+ +D VTSES++G+E + + Sbjct: 2227 GNYLKTLTASQHDTFTNPFEIVDINVVLGLDVVTSESLFGYETAEYTEDPSASTARPTEA 2286 Query: 1922 ERVVALPDTSAFIHSPIQAXXXXXXXXXXXXXXXXXXXVSFPKYNNYVRSKNKFDKYTRV 1981 ++ V LPDTSAF+ SP ++FPKYNNY+ N+FD Y+++ Sbjct: 2287 DQKVVLPDTSAFLSSP----------------AHFGPSITFPKYNNYMADPNRFDPYSKI 2330 Query: 1982 LLPLDLLGISN--NNLQDITDTNYETRAVFGYVQYSRNSSQLMPLRMDDSVSLRWGVNIT 2039 +PLD+LGI ++ + +AV YVQY + L+P R DDSVS+RWGV + Sbjct: 2331 RVPLDILGIKTLMQGELNVKKSLVNRKAVLSYVQY-KQLGALLPQRFDDSVSVRWGVEVA 2389 Query: 2040 IGSPILQIAVFVPES 2054 +GSP++ ++V VP + Sbjct: 2390 VGSPVITVSVLVPSN 2404 Score = 351 bits (864), Expect = 1e-94 Identities = 272/864 (31%), Positives = 417/864 (48%), Gaps = 74/864 (8%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 + + SP FE Y A V E G V +++A D + G V Y++ + D Sbjct: 253 ELKNQSPYFEQSLYVAVVEEEKEPGVYVTSVRARDPEGGT---VRYSMSSLL-------D 302 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134 A Q + +D +G + TRA LDRE V + V A D + P + T Sbjct: 303 ARS---------QALLVLDPVTGRVTTRARLDRESVDVHYFRVLAVDDSFPPR---TGTT 350 Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG- 193 T+ VN++D ND+ P F S+ E + V + +KATD D G N+ + Y+I+ Sbjct: 351 TLQVNVLDTNDHAPSFEWPEEEASIREGVPV--GSTVVTVKATDQDAGRNAEVEYSILST 408 Query: 194 ------GNTQ--MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT---Q 242 NT+ + F ID +G V+ LD E+ Y +++ D +P + T Sbjct: 409 TSSSGTANTEDALIFRIDPRTGVVTTRTPLDREKTEVYTVILSVSDQATPPSARKTANAT 468 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYS--IVRVQAYDADEGVNAELTYTMTDKD 300 L++ + D NDN P+F + + E++ + I R++A DAD G NA + Y + Sbjct: 469 LVVRVLDDNDNYPQFTERTYSAWIPEDLDYTANPVIARIRATDADSGNNAAVRYAIIG-- 526 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 GN +ID G V LD E+ Y++++ A DGG P RS T Sbjct: 527 --GNTQNTFSIDSMVGDVALVKPLDYESTRSYKIVIRAQDGGSPARSNTTQLLVHVGDVN 584 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI-----TGGNTRGRFS 413 F ++ ++E+ P G ++ + A DADE + ++ Y I TG +T F Sbjct: 585 DNAPRFYTSHFQESVSENVPVGYSILRIQAYDADEGANAQIKYTIGARDFTGASTE-NFP 643 Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFEN 471 IT G + + LD +Q RY TV A DSG +S +A V + +TD N+ P F+ Sbjct: 644 ITVNTETGWLYTTKQLDREQCSRYQFTVIAADSGEISKSASATVILTVTDVNDNDPYFDP 703 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 Y + V ED P GT V V+ATD D +A+I Y +++ + A Q G Sbjct: 704 KNYESVVSEDDPPGTPVTSVTATDPDE--DARIHYEITAGNTRGRFAIASQN-----GRG 756 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 IT + LD + ++LTVTA D G +DT V +++ D N+ PVF+ Y+ ++ Sbjct: 757 LITIAQPLDYKQEKRFVLTVTASDSG--GRTDTALVYVNISDANNFSPVFENAPYSVSVF 814 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPK--DREEGSFVIDPASGVIRTNKALDRES 649 EDA +GT+V V ATD+DVG N ++ Y LD D+ F+I+P +G I T K LDRE Sbjct: 815 EDAPIGTTVLVVSATDSDVGKNAQVTYSLDTDNGDQTASEFIINPQTGAITTTKPLDREI 874 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 V + L A DGG PP S T V I + D+ND+ PVFE+ I E+ +GT++ + Sbjct: 875 VPAYLLTVTARDGGIPPLSDTTDVEISVTDVNDNAPVFEAPQYQGSIPEDVLVGTSVLRV 934 Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY--ELVI 767 A D D N V Y+++ D +F++++ G + T LD ES K + + Sbjct: 935 SATDADTDLNGRVRYALE-DDGDGAFAVDSTTGI----IRTAKPLDRESVAKYILKAVAM 989 Query: 768 RAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDK 826 SP L V V I + DVND+ P ++ +II ++ P+G G + A+D D Sbjct: 990 DRGSPSLSTVVPVTIKIEDVNDSPPAFENDKIILYIAENS-PIGSTVGEIYAHDPDEGPN 1048 Query: 827 --LQYRILSGNNANLILLNETTGS 848 +QY ++ G ++N LN G+ Sbjct: 1049 AVVQYSVIGGEDSNSFALNIRPGA 1072 Score = 336 bits (825), Expect = 7e-90 Identities = 245/764 (32%), Positives = 376/764 (49%), Gaps = 41/764 (5%) Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 P F + Y V+E+ + ++A D + G +++ +Q +D ++G Sbjct: 259 PYFEQSLYVAVVEEEKE--PGVYVTSVRARDPEGGTVRYSMSSLLDARSQALLVLDPVTG 316 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 V+ LD E V + + A D P R+ TT L +N+ D ND+AP F + S+ Sbjct: 317 RVTTRARLDRESVDVHYFRVLAVDDSFPPRTGTTTLQVNVLDTNDHAPSFEWPEEEASIR 376 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTM---TDKDYTGNVD--LPITIDPRSGWVYTSG 322 E VP+G ++V V+A D D G NAE+ Y++ T T N + L IDPR+G V T Sbjct: 377 EGVPVGSTVVTVKATDQDAGRNAEVEYSILSTTSSSGTANTEDALIFRIDPRTGVVTTRT 436 Query: 323 QLDRETQAKYQLLVTATDGGDPP---RSATATXXXXXXXXXXXXXXFMPGQYEVELAED- 378 LDRE Y ++++ +D PP ++A AT F Y + ED Sbjct: 437 PLDREKTEVYTVILSVSDQATPPSARKTANATLVVRVLDDNDNYPQFTERTYSAWIPEDL 496 Query: 379 EPPGTPVVT-LTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435 + PV+ + ATDAD N + Y I GGNT+ FSI S G + + +PLD++ R Sbjct: 497 DYTANPVIARIRATDADSGNNAAVRYAIIGGNTQNTFSIDSMVGD--VALVKPLDYESTR 554 Query: 436 RYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 Y + + A D G RS+T + +++ D N+ AP F + + SV E+ P+G ++L + A Sbjct: 555 SYKIVIRAQDGGSPARSNTTQLLVHVGDVNDNAPRFYTSHFQESVSENVPVGYSILRIQA 614 Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553 D+D G NAQI Y++ + A + + +N +TG + T K LDRE S Y TV A Sbjct: 615 YDADEGANAQIKYTIGARDFTGA-STENFPITVNTETGWLYTTKQLDREQCSRYQFTVIA 673 Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613 D G S S + V ++V DVNDN+P F + Y + + ED GT V+ V ATD D + Sbjct: 674 ADSGEISKSASATVILTVTDVNDNDPYFDPKNYESVVSEDDPPGTPVTSVTATDPDE--D 731 Query: 614 GRIHYELDPKDREEGSFVI--DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671 RIHYE+ G F I G+I + LD + L A D G ++ T Sbjct: 732 ARIHYEI-TAGNTRGRFAIASQNGRGLITIAQPLDYKQEKRFVLTVTASDSG--GRTDTA 788 Query: 672 IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI---KG 728 +V++ I D N+ PVFE+ + + E++PIGTT+ + A D D G NA V YS+ G Sbjct: 789 LVYVNISDANNFSPVFENAPYSVSVFEDAPIGTTVLVVSATDSDVGKNAQVTYSLDTDNG 848 Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVT 785 ++ F + + G+ + T LD E Y L + A PPL + VEI VT Sbjct: 849 DQTASEFIINPQTGA----ITTTKPLDREIV-PAYLLTVTARDGGIPPLSDTTDVEISVT 903 Query: 786 DVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDA--DVTDKLQYRILSGNNANLILLN 843 DVNDNAPV + Q + +D RV A DA D+ +++Y L + ++ Sbjct: 904 DVNDNAPVFEAPQYQGSIPEDVLVGTSVLRVSATDADTDLNGRVRY-ALEDDGDGAFAVD 962 Query: 844 ETTGSM-TLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886 TTG + T P +V K V++ G + ++ +++++ Sbjct: 963 STTGIIRTAKPLDRESVAKYILKAVAMDRGSPSLSTVVPVTIKI 1006 Score = 235 bits (574), Expect = 2e-59 Identities = 179/654 (27%), Positives = 303/654 (46%), Gaps = 47/654 (7%) Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 R++ + +P F SL+ V E G + V+A D + G + Y+M+ Sbjct: 252 RELKNQSPYFEQSLYVAVVEEEKEPGVYVTSVRARDPEGGT---VRYSMSSL-LDARSQA 307 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 + +DP +G V T +LDRE+ + V A D PPR+ T T F Sbjct: 308 LLVLDPVTGRVTTRARLDRESVDVHYFRVLAVDDSFPPRTGTTTLQVNVLDTNDHAPSFE 367 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITG-------GNTRGRFSITSQN 418 + E + E P G+ VVT+ ATD D + + Y I NT Sbjct: 368 WPEEEASIREGVPVGSTVVTVKATDQDAGRNAEVEYSILSTTSSSGTANTEDALIFRIDP 427 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATD-----SGGRSDTAMVQINITDANNYAPVFENAP 473 G++T PLD ++ Y + +S +D S ++ A + + + D N+ P F Sbjct: 428 RTGVVTTRTPLDREKTEVYTVILSVSDQATPPSARKTANATLVVRVLDDNDNYPQFTERT 487 Query: 474 YTASVFEDAPIGTTVLV--VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 Y+A + ED ++ + ATD+D G NA + Y++ + F I+ G Sbjct: 488 YSAWIPEDLDYTANPVIARIRATDADSGNNAAVRYAIIG-------GNTQNTFSIDSMVG 540 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 + K LD E+ Y + + A+DGG P+ S+TT + + V DVNDN P F + ++ Sbjct: 541 DVALVKPLDYESTRSYKIVIRAQDGGSPARSNTTQLLVHVGDVNDNAPRFYTSHFQESVS 600 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKD-----REEGSFVIDPASGVIRTNKALD 646 E+ VG S+ ++ A DAD G N +I Y + +D E ++ +G + T K LD Sbjct: 601 ENVPVGYSILRIQAYDADEGANAQIKYTIGARDFTGASTENFPITVNTETGWLYTTKQLD 660 Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706 RE + + +A D G +S++ V + + D+ND+ P F+ +SE+ P GT + Sbjct: 661 REQCSRYQFTVIAADSGEISKSASATVILTVTDVNDNDPYFDPKNYESVVSEDDPPGTPV 720 Query: 707 GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYEL 765 + A DPDE +A +HY I G+ F++ ++ G L+T+ LDY+ K++ L Sbjct: 721 TSVTATDPDE--DARIHYEITAGNTRGRFAIASQNGRG---LITIAQPLDYKQ-EKRFVL 774 Query: 766 VIRAASPPLWNDVR-VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR-VPAYDADV 823 + A+ D V + ++D N+ +PV ++ + ++D P+G V A D+DV Sbjct: 775 TVTASDSGGRTDTALVYVNISDANNFSPVFENAPYSVSVFEDA-PIGTTVLVVSATDSDV 833 Query: 824 TDKLQ--YRILSGN---NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 Q Y + + N A+ ++N TG++T + L+ + + V+ DG Sbjct: 834 GKNAQVTYSLDTDNGDQTASEFIINPQTGAITTTKPLDREIVPAYLLTVTARDG 887 Score = 193 bits (470), Expect = 7e-47 Identities = 93/163 (57%), Positives = 121/163 (74%), Gaps = 5/163 (3%) Query: 2168 YRSLSGIRLKKPIRLQIWLDINRETFGSRTNPQCVHWSTLRGSGEWSRVGCHTEIDYDWS 2227 Y SL+GI L+ P+++ +WL ++ +RTNPQCVHWST RG GEWSR+GC TE + D Sbjct: 2407 YMSLTGIPLQSPVQISLWLS-EKDDIKTRTNPQCVHWSTARGVGEWSRMGCTTESEDDSL 2465 Query: 2228 PYSEEPLLINCTCNHLSTFAVLVDEVDVEFIPEPSLLESVTSYTAFSISLPLLLTSWAAL 2287 + ++NC+C LSTFA+L D +D E++PEPSLLE VTSY+AF ++LPLLL++ L Sbjct: 2466 SFGT---IVNCSCFQLSTFAILTDVLDPEYVPEPSLLEDVTSYSAFMLALPLLLSALLIL 2522 Query: 2288 CLIRGGAATVSNSIHKHLIFSVFMAELLYLIALKARTSLVQNE 2330 LIRGG T SNSIHK+L+ VF AE+LYLIALKAR+ LV NE Sbjct: 2523 ALIRGG-GTNSNSIHKNLVMCVFFAEVLYLIALKARSPLVSNE 2564 Score = 111 bits (266), Expect = 4e-22 Identities = 91/328 (27%), Positives = 145/328 (44%), Gaps = 22/328 (6%) Query: 563 DTTDVEISVV-DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621 D TD+ V ++ + P F+Q LY A + E+ G V+ V A D + G + Y + Sbjct: 242 DDTDLGRRVRRELKNQSPYFEQSLYVAVVEEEKEPGVYVTSVRARDPE---GGTVRYSMS 298 Query: 622 P--KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679 R + V+DP +G + T LDRESV H + +A+D PP++ T + + + D Sbjct: 299 SLLDARSQALLVLDPVTGRVTTRARLDRESVDVHYFRVLAVDDSFPPRTGTTTLQVNVLD 358 Query: 680 INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-----KGGDDSNS 734 ND P FE I E P+G+T+ ++A D D G NA V YSI G + Sbjct: 359 TNDHAPSFEWPEEEASIREGVPVGSTVVTVKATDQDAGRNAEVEYSILSTTSSSGTANTE 418 Query: 735 FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN---DVRVEILVTDVN 788 +L R + T LD E + Y +++ A+PP + + + V D N Sbjct: 419 DALIFRIDPRTGVVTTRTPLDREK-TEVYTVILSVSDQATPPSARKTANATLVVRVLDDN 477 Query: 789 DNAPVMKDFQIIFNNYKDC-FPVGP-FGRVPAYDADVTDK--LQYRILSGNNANLILLNE 844 DN P + +D + P R+ A DAD + ++Y I+ GN N ++ Sbjct: 478 DNYPQFTERTYSAWIPEDLDYTANPVIARIRATDADSGNNAAVRYAIIGGNTQNTFSIDS 537 Query: 845 TTGSMTLSPQLNTNVPKLATMEVSVTDG 872 G + L L+ + + + DG Sbjct: 538 MVGDVALVKPLDYESTRSYKIVIRAQDG 565 Score = 91.9 bits (218), Expect = 2e-16 Identities = 67/223 (30%), Positives = 96/223 (43%), Gaps = 12/223 (5%) Query: 2330 EPVVWWVVIPXXXXXXXXXXXXXXXXXXXFTVRDHVTGFGNLRMLLAVSIVCLPLLCVAW 2389 E V+W ++ P FT+++H+ GFGNLR LL +S+ LPLL W Sbjct: 2645 ETVIWSLIGPICLAIFVNFCILVMSIRAAFTLKEHIMGFGNLRTLLWLSVASLPLLGSTW 2704 Query: 2390 ASALLLGSEAGGRRXXXXXXXXXXXXXXXIAASLGYIAFNVRVRDNLKRTVLRCMGKKVP 2449 +L SE + +GY N RVR NL ++LRC+GKK P Sbjct: 2705 TLTVLNASENSPTLSYLLSIAVVVHASFSL---IGYCFINGRVRRNLYLSLLRCIGKKTP 2761 Query: 2450 LADTSVIISSSAHNLSQVNRSSLAYHSSTEPGRQ--MRNIGIXXXXXXXXXXXXXXXXXX 2507 L + S+ SS+ N++ +RS+LAY SST G + R + + Sbjct: 2762 LLEGSMGNGSSSQNVNGHSRSALAY-SSTYSGAESVCRRVHVGVSTSSTTSRSTNKTGSS 2820 Query: 2508 -XXXDGQLRHXXXXXXXXXXXASDMPAYL--RGFDSSLHTRKD 2547 D LRH SD YL R S+LH+R++ Sbjct: 2821 PYRSDTHLRHTSTSTSNYN---SDRDPYLSSRSHRSTLHSRQE 2860 Score = 36.7 bits (81), Expect = 9.2 Identities = 25/55 (45%), Positives = 30/55 (54%), Gaps = 7/55 (12%) Query: 2572 SPRWPSHVREDQ-SRPEM----GRWSQETGSDNEGANMGIATPSPNPLPNPDLTS 2621 +PRW S + E S M +WS T SDNE A+ T SPNPLP PD+ S Sbjct: 2950 APRWSSQLPEAYLSSNAMDVRGSQWSGGTISDNEMASN--KTSSPNPLPYPDMNS 3002 >UniRef50_Q4S7X0 Cluster: Chromosome 9 SCAF14710, whole genome shotgun sequence; n=6; Clupeocephala|Rep: Chromosome 9 SCAF14710, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 4006 Score = 1381 bits (3421), Expect = 0.0 Identities = 775/1980 (39%), Positives = 1107/1980 (55%), Gaps = 191/1980 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D NDHSP+FE +Y ++RE G +L L+ATD D NA + Y D + Sbjct: 1024 ITVSDRNDHSPIFEQTEYRETIRENVEEGYPILQLRATDSDSPTNANIRYRF---IGDMV 1080 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F ID RSG + TR +DRE YT+ V+A+DQ R Sbjct: 1081 -------------AVARAAFEIDPRSGLITTRGVVDRELNEHYTLQVEASDQGKEPGPR- 1126 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+T + + ++D+NDN PQFSEK Y V+V E+ V + I ++ ATD D +N+A+ Y Sbjct: 1127 SATVKVFITVLDENDNVPQFSEKRYVVAVKEN--VRPHSEILRVSATDRDKDSNAAVHYN 1184 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIRD 249 II GN++ QFSIDS++G++ +V LDYE R Y L +RAQD G P SN T ++ + + D Sbjct: 1185 IISGNSRGQFSIDSVTGEIQVVAPLDYEAEREYTLRVRAQDNGRPPLSNNTGIVSVQVTD 1244 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 VNDN P F ++ FQ SV E+ P+G SI+ +QA D D G NA L Y +T + D P Sbjct: 1245 VNDNPPIFVSTPFQASVLESSPVGSSILHIQAIDTDSGDNARLEYKLTGT----SSDTPF 1300 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 I+ +GWV LDRE+ Y V A D G PP SATA+ F+ Sbjct: 1301 IINSATGWVTVRSTLDRESVEHYFFGVEARDYGTPPLSATASVTITVMDVNDNHPEFLQK 1360 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 +Y L ED GT VVT+TA D D ++ + Y+ITGGNTR RF+I++ G GL+++A PL Sbjct: 1361 EYYARLNEDAAVGTSVVTVTAVDRDVNSAVTYQITGGNTRNRFAISTAGGAGLLSLALPL 1420 Query: 430 DFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 D+KQERRYVLTV+A+D DT V INITDAN + PVF++A Y+ SV ED+P G+ V+ Sbjct: 1421 DYKQERRYVLTVTASDR-TLHDTCQVHINITDANTHRPVFQSAHYSVSVNEDSPPGSLVV 1479 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 ++SATD DVG NA+ITY L I QF I+ TGAIT LD E Y L Sbjct: 1480 MISATDDDVGENARITYLLEDNI---------PQFRIDSATGAITLQAELDYEDQMTYTL 1530 Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 +TA+D G+P SDTT VE++V DVNDN P F Y ++ EDA TSV Q+ ATD D Sbjct: 1531 AITAKDNGIPQKSDTTYVEVNVNDVNDNAPQFLSPRYQGSVSEDAPPFTSVLQISATDRD 1590 Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669 NGR+ Y + +G F I+P SG++RT +A PPQ + Sbjct: 1591 AHANGRVQYTFQNGEDGDGDFTIEPTSGILRTIEA-------------------CPPQRT 1631 Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729 V + + + D+ND PVF +D + ENS +G+ + +I A DPDEG NA + Y I G Sbjct: 1632 PVHIQVTVLDVNDKAPVFPADDFEVLVKENSAVGSVVAQITATDPDEGANAQIMYQIVEG 1691 Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVND 789 + F ++ G EL +++DLDYE+ R +Y +V++A S PL + V I + D ND Sbjct: 1692 NIPEIFQMDIFSG----ELTSLIDLDYET-RNEYVIVVQATSAPLVSRATVRIKLVDQND 1746 Query: 790 NAPVMKDFQIIFNNY----KDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNET 845 N P ++DFQIIFNN+ + FP G GR+PA+D DV+D+L Y I GN +L+LLN T Sbjct: 1747 NRPTLQDFQIIFNNFVSNRSNSFPSGVIGRIPAHDPDVSDRLYYTIDRGNELHLLLLNHT 1806 Query: 846 TGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTA 905 +G + LS +L+ N P +A M ++VTDG++ I A L V +ITE+ML +S+TVRL +M+ Sbjct: 1807 SGEIRLSRKLDNNRPLVAPMLITVTDGIHSISAQCVLRVLIITEDMLGSSVTVRLQNMSQ 1866 Query: 906 EQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVT-GNILNVSFSARRPDAEVGVAG 964 E FLSPLLG F++G++A++ P E+++IF++Q D D G ILNVSFSA P G Sbjct: 1867 EHFLSPLLGNFLEGVSAVLSVPVEDVFIFNIQPDLDAAPGRILNVSFSAALP----GGLF 1922 Query: 965 DPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASG 1024 PS L E++YL+R L L ++VLPFDDN+C+ EPC N+ +C++VL+F +++ Sbjct: 1923 FPS-----EALEEQLYLNRPRLTSLTQMEVLPFDDNVCLREPCKNYMKCVSVLRFNSSAP 1977 Query: 1025 FVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSIC---RSGSQCVA 1081 F++S S+LFRPI+P+ C+CP GFTG CET + +G +C G C+ Sbjct: 1978 FISSPSILFRPIHPIAGLRCRCPVGFTGDYCETEINLCYSNPCLNGGVCAPREGGFTCIC 2037 Query: 1082 R------------REGGI---LCQG-------------CSI-DAAYTTAVCELRARSFPV 1112 R R+GG +C+ C + AY C + ARSFP Sbjct: 2038 RENYTGDRCEFDHRQGGCVPGVCRNGGTCLELSRGGFRCECPEGAYEPPYCAVTARSFPP 2097 Query: 1113 SSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRGGGPGL 1172 SF F GL++R + + L FAT SGLL YNGR+NE+HDF+ALE+ + + Sbjct: 2098 KSFAMFRGLRQRFHLTISLTFATLENSGLLFYNGRFNEKHDFIALEIQEGQ--------V 2149 Query: 1173 RFSFSLGGGKSEIT--VEGNVGDGSWHTVEIEYFNRTITMI----------------LDD 1214 +S G +++T + G V DG+WH+V I Y+N+ I +DD Sbjct: 2150 VLKYSTGESSTQVTPFLPGGVSDGNWHSVHIHYYNKPKRSIGGEAQGPSDEKIAVVRVDD 2209 Query: 1215 CDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSF 1274 CD LSL + G Y+CA + + + LDLTGPL +GG+PN +F Sbjct: 2210 CDAALSLRFSTQLG-NYSCA----------AQGKQSSSKKSLDLTGPLFLGGVPNGADNF 2258 Query: 1275 QVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDT 1334 +++F+GC+ DF+ID+K +DL ++A+NGT AGC K C+S PC NG C W+T Sbjct: 2259 PFSSREFIGCLKDFHIDNKQLDLAGFIANNGTTAGCSAKTPFCNSNPCQNGGTCRVGWET 2318 Query: 1335 YICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLR-PIQLPWLNALSIRTRQRDAFVM 1393 ++CDC G+ GKDC+ P RF G+ + ++ I PW L RTR R+ ++ Sbjct: 2319 FLCDCPLGYGGKDCSHVMPHPHRFLGNSVQWWDLKNEVTISTPWYLGLVFRTRSREGTLL 2378 Query: 1394 SIQL--KSGLLHYSYNGETMY-------------LPMATLSDGAWH--RIEIKWLGTD-- 1434 Q + LL N + ++ L ++DG WH ++E++ + +D Sbjct: 2379 QAQAGQYTSLLFQVVNSQLVFSVTRGAARPVRLRLDQVLVADGRWHDLQLELRDVRSDRE 2438 Query: 1435 ----ISVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGLLASDVGFFEGCIQDVR 1490 ++ +D+G+ + ++ N+I G + + +GG+ +G + + + GCIQ VR Sbjct: 2439 TRYVATLRLDFGIYQGTV-IVGNEIHGLKVKHLHVGGV-FGSGKVQNGI---RGCIQGVR 2493 Query: 1491 IGTAQSL--LNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC 1548 +G L PT NV GC C+ S CP +S+C W+ TC C+ G G C Sbjct: 2494 LGVRPDAPPLRPPTRTVNVEAGCNVGNYCVSSPCPTHSRCADQWERHTCVCDPGYYGKSC 2553 Query: 1549 VSACELGPC-GAARC-VPDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGP 1606 AC L PC A+C + GY C C G C +CP GWWG CGP Sbjct: 2554 TDACHLNPCENEAQCHRKPSSSHGYVCDC--GDNHFGQYCQHRSDHQCPRGWWGSPTCGP 2611 Query: 1607 CACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCR 1666 C CD +G+ P+CNK +G CHCKE HY P G+ CLPC CY GS + SC+A TGQC CR Sbjct: 2612 CDCDTDKGFDPNCNKTSGHCHCKEFHYHPRGSDTCLPCDCYPVGSFSRSCDAETGQCQCR 2671 Query: 1667 PGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSG 1726 PGVIGR C+AC N +AEVT NSGCEV+YDGCP++ G+WWPRTKF P G Sbjct: 2672 PGVIGRQCNACDNPFAEVT-NSGCEVIYDGCPKTITQGIWWPRTKF--------TPACGG 2722 Query: 1727 RATRTCDETKDVPWQDPDMFNCTTATFYQLRKQLHKIETGELTMNTFVGVRVAADLSTAC 1786 A R CD + W +P+++NCT+ F +L L +E E ++T + ++A L Sbjct: 2723 AAIRHCDVERG--WLEPELYNCTSPPFVELNAALDSLERNETELSTIMEKKLAHQLRDVT 2780 Query: 1787 ANTPRLYGADVVVAEGILLELMDYELRQAGLNLTHSQDKDYVRNLLKSTNTILNVEYERE 1846 T RLYG D+ +AE +L L+++E +Q+G LT +QD + NL+++ + +L Sbjct: 2781 EATARLYGNDLHIAERLLSRLLNFETQQSGFGLTATQDAYFNENLIRACSALLGPGTSGL 2840 Query: 1847 WKRI----RELTGHGAELLVQKFDEYIAVLAESQHDTYTSPFEIVTKDVVISVDTVTSES 1902 W+ + + G G L +Y LA++ TY +P +V ++V+++D V +++ Sbjct: 2841 WRALIQSQNHIQGGGPAELTGLLRQYSQNLAKNMKLTYLNPVALVAPNLVMNLDRVETQT 2900 Score = 345 bits (849), Expect = 8e-93 Identities = 238/711 (33%), Positives = 360/711 (50%), Gaps = 42/711 (5%) Query: 145 DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA---IIGGNTQMQFS 201 + +P F + Y V V E+ + ++ + A+D D G + Y+ ++ + F Sbjct: 923 NRHPFFPQYNYQVQVAENQPPGTSVIL--MSASDPDPGDAGRVSYSMAPLMNSRSSDYFH 980 Query: 202 IDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261 I +G ++ +TLD E + + + A D GS S TT + I + D ND++P F + Sbjct: 981 IHPETGLITTTQTLDREHMDLHYFRVTATDYGSSRLSGTTMVAITVSDRNDHSPIFEQTE 1040 Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321 ++E++ ENV GY I++++A D+D NA + Y D IDPRSG + T Sbjct: 1041 YRETIRENVEEGYPILQLRATDSDSPTNANIRYRFIG-DMVAVARAAFEIDPRSGLITTR 1099 Query: 322 GQLDRETQAKYQLLVTATDGG-DP-PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE 379 G +DRE Y L V A+D G +P PRSAT F +Y V + E+ Sbjct: 1100 GVVDRELNEHYTLQVEASDQGKEPGPRSATVKVFITVLDENDNVPQFSEKRYVVAVKENV 1159 Query: 380 PPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437 P + ++ ++ATD D+D+ +HY I GN+RG+FSI S G I V PLD++ ER Y Sbjct: 1160 RPHSEILRVSATDRDKDSNAAVHYNIISGNSRGQFSIDSVTGE--IQVVAPLDYEAEREY 1217 Query: 438 VLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494 L V A D+G ++T +V + +TD N+ P+F + P+ ASV E +P+G+++L + A Sbjct: 1218 TLRVRAQDNGRPPLSNNTGIVSVQVTDVNDNPPIFVSTPFQASVLESSPVGSSILHIQAI 1277 Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554 D+D G NA++ Y L+ S D F+IN TG +T LDRE++ Y V AR Sbjct: 1278 DTDSGDNARLEYKLTGTSS-------DTPFIINSATGWVTVRSTLDRESVEHYFFGVEAR 1330 Query: 555 DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614 D G P LS T V I+V+DVNDN P F Q+ Y A + EDA VGTSV V A D DV N Sbjct: 1331 DYGTPPLSATASVTITVMDVNDNHPEFLQKEYYARLNEDAAVGTSVVTVTAVDRDV--NS 1388 Query: 615 RIHYELDPKDREEGSFVIDPA--SGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672 + Y++ + F I A +G++ LD + + L A D T Sbjct: 1389 AVTYQITGGNTRN-RFAISTAGGAGLLSLALPLDYKQERRYVLTVTASDRTL---HDTCQ 1444 Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732 VHI I D N PVF+S + ++E+SP G+ + I A D D G NA + Y ++ D+ Sbjct: 1445 VHINITDANTHRPVFQSAHYSVSVNEDSPPGSLVVMISATDDDVGENARITYLLE--DNI 1502 Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVND 789 F +++ G+ + +LDYE + Y L I A P + VE+ V DVND Sbjct: 1503 PQFRIDSATGA----ITLQAELDYED-QMTYTLAITAKDNGIPQKSDTTYVEVNVNDVND 1557 Query: 790 NAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNAN 838 NAP + + +D P ++ A D D ++QY +G + + Sbjct: 1558 NAPQFLSPRYQGSVSEDAPPFTSVLQISATDRDAHANGRVQYTFQNGEDGD 1608 Score = 330 bits (812), Expect = 2e-88 Identities = 264/852 (30%), Positives = 400/852 (46%), Gaps = 85/852 (9%) Query: 17 NDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAX 76 N H P F Y+ V E GT+V+ + A+D D G V Y++ A +N + Sbjct: 923 NRH-PFFPQYNYQVQVAENQPPGTSVILMSASDPDPGDAGRVSYSM----APLMNSRSS- 976 Query: 77 XXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATI 136 D F I +G + T +LDRE + + V ATD S RLS T + Sbjct: 977 -----------DYFHIHPETGLITTTQTLDREHMDLHYFRVTATDYGS---SRLSGTTMV 1022 Query: 137 HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNT 196 + + D ND+ P F + Y ++ E++ + I +++ATD+D N+ IRY IG Sbjct: 1023 AITVSDRNDHSPIFEQTEYRETIRENVE--EGYPILQLRATDSDSPTNANIRYRFIGDMV 1080 Query: 197 QMQ---FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS--RSNTTQLLINIRDVN 251 + F ID SG ++ +D E Y L + A D G RS T ++ I + D N Sbjct: 1081 AVARAAFEIDPRSGLITTRGVVDRELNEHYTLQVEASDQGKEPGPRSATVKVFITVLDEN 1140 Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311 DN P+F + +V ENV I+RV A D D+ NA + Y + +GN +I Sbjct: 1141 DNVPQFSEKRYVVAVKENVRPHSEILRVSATDRDKDSNAAVHYNII----SGNSRGQFSI 1196 Query: 312 DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA-TATXXXXXXXXXXXXXXFMPGQ 370 D +G + LD E + +Y L V A D G PP S T F+ Sbjct: 1197 DSVTGEIQVVAPLDYEAEREYTLRVRAQDNGRPPLSNNTGIVSVQVTDVNDNPPIFVSTP 1256 Query: 371 YEVELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 ++ + E P G+ ++ + A D D DN RL Y++TG ++ F I S G +TV Sbjct: 1257 FQASVLESSPVGSSILHIQAIDTDSGDNARLEYKLTGTSSDTPFIINSATG--WVTVRST 1314 Query: 429 LDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD + Y V A D G S TA V I + D N+ P F Y A + EDA +GT Sbjct: 1315 LDRESVEHYFFGVEARDYGTPPLSATASVTITVMDVNDNHPEFLQKEYYARLNEDAAVGT 1374 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA--ITTNKLLDRETM 544 +V+ V+A D DV N+ +TY ++ + +F I+ GA ++ LD + Sbjct: 1375 SVVTVTAVDRDV--NSAVTYQITG-------GNTRNRFAISTAGGAGLLSLALPLDYKQE 1425 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 Y+LTVTA D +L DT V I++ D N + PVF+ Y+ ++ ED+ G+ V + Sbjct: 1426 RRYVLTVTASDR---TLHDTCQVHINITDANTHRPVFQSAHYSVSVNEDSPPGSLVVMIS 1482 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 ATD DVG N RI Y L+ + F ID A+G I LD E T+ L A D G Sbjct: 1483 ATDDDVGENARITYLLEDNIPQ---FRIDSATGAITLQAELDYEDQMTYTLAITAKDNGI 1539 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 P +S T V + + D+ND+ P F S +SE++P T++ +I A D D N V Y Sbjct: 1540 PQKSDTTYVEVNVNDVNDNAPQFLSPRYQGSVSEDAPPFTSVLQISATDRDAHANGRVQY 1599 Query: 725 SIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEIL 783 + + G+D + F++E G ++ ++ A PP V +++ Sbjct: 1600 TFQNGEDGDGDFTIEPTSG-----ILRTIE----------------ACPPQRTPVHIQVT 1638 Query: 784 VTDVNDNAPVM--KDFQIIFNNYKDCFPVGP-FGRVPAYDAD--VTDKLQYRILSGNNAN 838 V DVND APV DF+++ K+ VG ++ A D D ++ Y+I+ GN Sbjct: 1639 VLDVNDKAPVFPADDFEVL---VKENSAVGSVVAQITATDPDEGANAQIMYQIVEGNIPE 1695 Query: 839 LILLNETTGSMT 850 + ++ +G +T Sbjct: 1696 IFQMDIFSGELT 1707 Score = 270 bits (662), Expect = 4e-70 Identities = 203/666 (30%), Positives = 305/666 (45%), Gaps = 28/666 (4%) Query: 218 EQVRSYRLVIRAQDGGSPSRSNTTQLLI--NIRDVNDNAPRFYTSLFQESVSENVPIGYS 275 EQ RL+I D S ++ R + P F +Q V+EN P G S Sbjct: 887 EQSSLERLIIAGDDKTSQGEGEEKNRMLWSRSRRAANRHPFFPQYNYQVQVAENQPPGTS 946 Query: 276 IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL 335 ++ + A D D G ++Y+M + + D I P +G + T+ LDRE + Sbjct: 947 VILMSASDPDPGDAGRVSYSMAPLMNSRSSDY-FHIHPETGLITTTQTLDREHMDLHYFR 1005 Query: 336 VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395 VTATD G S T F +Y + E+ G P++ L ATD+D Sbjct: 1006 VTATDYGSSRLSGTTMVAITVSDRNDHSPIFEQTEYRETIRENVEEGYPILQLRATDSDS 1065 Query: 396 DNR--LHYEITGGNT---RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG-- 448 + Y G R F I ++G LIT +D + Y L V A+D G Sbjct: 1066 PTNANIRYRFIGDMVAVARAAFEIDPRSG--LITTRGVVDRELNEHYTLQVEASDQGKEP 1123 Query: 449 --RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506 RS T V I + D N+ P F Y +V E+ + +L VSATD D NA + Y Sbjct: 1124 GPRSATVKVFITVLDENDNVPQFSEKRYVVAVKENVRPHSEILRVSATDRDKDSNAAVHY 1183 Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566 ++ S S QF I+ TG I LD E Y L V A+D G P LS+ T Sbjct: 1184 NIISGNSRG-------QFSIDSVTGEIQVVAPLDYEAEREYTLRVRAQDNGRPPLSNNTG 1236 Query: 567 -VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625 V + V DVNDN P+F + A+++E + VG+S+ + A D D G N R+ Y+L Sbjct: 1237 IVSVQVTDVNDNPPIFVSTPFQASVLESSPVGSSILHIQAIDTDSGDNARLEYKLTGTSS 1296 Query: 626 EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685 + F+I+ A+G + LDRESV + A D GTPP S+T V I + D+ND+ P Sbjct: 1297 DT-PFIINSATGWVTVRSTLDRESVEHYFFGVEARDYGTPPLSATASVTITVMDVNDNHP 1355 Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745 F ++E++ +GT++ + A D D N+ V Y I GG+ N F++ T G+ Sbjct: 1356 EFLQKEYYARLNEDAAVGTSVVTVTAVDRDV--NSAVTYQITGGNTRNRFAISTAGGAGL 1413 Query: 746 AELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYK 805 L + LDY+ R+ Y L + A+ L + +V I +TD N + PV + + + Sbjct: 1414 LSLA--LPLDYKQERR-YVLTVTASDRTLHDTCQVHINITDANTHRPVFQSAHYSVSVNE 1470 Query: 806 DCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATM 865 D P + A D DV + + L +N ++ TG++TL +L+ T+ Sbjct: 1471 DSPPGSLVVMISATDDDVGENARITYLLEDNIPQFRIDSATGAITLQAELDYEDQMTYTL 1530 Query: 866 EVSVTD 871 ++ D Sbjct: 1531 AITAKD 1536 Score = 239 bits (585), Expect = 8e-61 Identities = 169/527 (32%), Positives = 255/527 (48%), Gaps = 21/527 (3%) Query: 371 YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITG-GNTRGRFSITSQNGRGLITVAQ 427 Y+V++AE++PPGT V+ ++A+D D + R+ Y + N+R GLIT Q Sbjct: 933 YQVQVAENQPPGTSVILMSASDPDPGDAGRVSYSMAPLMNSRSSDYFHIHPETGLITTTQ 992 Query: 428 PLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 LD + + V+ATD G S T MV I ++D N+++P+FE Y ++ E+ G Sbjct: 993 TLDREHMDLHYFRVTATDYGSSRLSGTTMVAITVSDRNDHSPIFEQTEYRETIRENVEEG 1052 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 +L + ATDSD NA I Y ++ AVA F I+P++G ITT ++DRE Sbjct: 1053 YPILQLRATDSDSPTNANIRYRFIGDMV--AVAR--AAFEIDPRSGLITTRGVVDRELNE 1108 Query: 546 GYLLTVTARDGGVPS--LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 Y L V A D G S T V I+V+D NDN P F ++ Y + E+ + + +V Sbjct: 1109 HYTLQVEASDQGKEPGPRSATVKVFITVLDENDNVPQFSEKRYVVAVKENVRPHSEILRV 1168 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 ATD D N +HY + G F ID +G I+ LD E+ + L+ A D G Sbjct: 1169 SATDRDKDSNAAVHYNII-SGNSRGQFSIDSVTGEIQVVAPLDYEAEREYTLRVRAQDNG 1227 Query: 664 TPPQSS-TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 PP S+ T IV +++ D+ND+PP+F S + E+SP+G++I I+A D D G NA + Sbjct: 1228 RPPLSNNTGIVSVQVTDVNDNPPIFVSTPFQASVLESSPVGSSILHIQAIDTDSGDNARL 1287 Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVR 779 Y + G F + + G + LD ES + Y + A +PPL Sbjct: 1288 EYKLTGTSSDTPFIINSATGW----VTVRSTLDRESV-EHYFFGVEARDYGTPPLSATAS 1342 Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANL 839 V I V DVNDN P + +D V A D DV + Y+I GN N Sbjct: 1343 VTITVMDVNDNHPEFLQKEYYARLNEDAAVGTSVVTVTAVDRDVNSAVTYQITGGNTRNR 1402 Query: 840 ILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886 ++ G+ LS L + + ++VT + Q+ + + Sbjct: 1403 FAISTAGGAGLLSLALPLDYKQERRYVLTVTASDRTLHDTCQVHINI 1449 Score = 86.6 bits (205), Expect = 9e-15 Identities = 67/230 (29%), Positives = 107/230 (46%), Gaps = 33/230 (14%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 +H Q+ VLD ND +PVF +E V+E ++ G+ V + ATD D G NA++ Y I Sbjct: 1633 VHIQVTVLDVNDKAPVFPADDFEVLVKENSAVGSVVAQITATDPDEGANAQIMYQI---- 1688 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 + ++F++D SG L + LD E Y ++V+AT Sbjct: 1689 ---------------VEGNIPEIFQMDIFSGELTSLIDLDYETRNEYVIVVQAT------ 1727 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP----VIAKIKATDADVG 182 S L S AT+ + ++D NDN P + + + + +S N VI +I A D DV Sbjct: 1728 SAPLVSRATVRIKLVDQNDNRPTLQD--FQIIFNNFVSNRSNSFPSGVIGRIPAHDPDV- 1784 Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232 + + Y I GN ++ SG++ L + LD + ++I DG Sbjct: 1785 -SDRLYYTIDRGNELHLLLLNHTSGEIRLSRKLDNNRPLVAPMLITVTDG 1833 Score = 50.8 bits (116), Expect = 5e-04 Identities = 23/54 (42%), Positives = 34/54 (62%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIE 63 ++NV D ND++P F +Y+ SV E A T+VL + ATD+D N V+YT + Sbjct: 1549 EVNVNDVNDNAPQFLSPRYQGSVSEDAPPFTSVLQISATDRDAHANGRVQYTFQ 1602 Score = 48.8 bits (111), Expect = 0.002 Identities = 41/146 (28%), Positives = 68/146 (46%), Gaps = 12/146 (8%) Query: 2176 LKKPIRLQIWLDINRETFGSRTNPQCVHWSTLRGSGEWSRVGCHTEIDYDWSPYSEEPLL 2235 L +P+ L+ L ET +R+ P CV W+ S + GC T D Sbjct: 3049 LDQPVLLEFKL---LET-ANRSKPLCVQWNH---SSQHDLGGCWTV--RDCMVVYRNTSH 3099 Query: 2236 INCTCNHLSTFAVLVDEVDVEFIPEPSLLESVTSYTAFSIS-LPLLLTSWAALCLIRGGA 2294 + C C L TF VL+D E + ++ +Y+ +S L L+LT CL G Sbjct: 3100 VRCQCQRLGTFGVLMDSSQREQLEGDLETLALVTYSTLCLSMLALILTVLVLSCL--RGL 3157 Query: 2295 ATVSNSIHKHLIFSVFMAELLYLIAL 2320 + + SIH + ++F++EL++L+ + Sbjct: 3158 KSNTRSIHSNTAAAMFLSELVFLLGI 3183 >UniRef50_Q9NYQ6 Cluster: Cadherin EGF LAG seven-pass G-type receptor 1 precursor; n=45; Eukaryota|Rep: Cadherin EGF LAG seven-pass G-type receptor 1 precursor - Homo sapiens (Human) Length = 3014 Score = 922 bits (2281), Expect = 0.0 Identities = 494/1116 (44%), Positives = 688/1116 (61%), Gaps = 73/1116 (6%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72 V D NDHSPVFE +Y VRE G VLT++A+D+D NA + Y + Sbjct: 343 VKDTNDHSPVFEQSEYRERVRENLEVGYEVLTIRASDRDSPINANLRYRV---------- 392 Query: 73 EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132 DVF+++ SG + TRA LDRE+ A Y +LV+A DQ LS+ Sbjct: 393 ----------LGGAWDVFQLNESSGVVSTRAVLDREEAAEYQLLVEANDQGRNPGP-LSA 441 Query: 133 TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192 TAT+++ + D+NDNYPQFSE+ Y V V ED+ + N + +++ATD D G N+AI Y+I+ Sbjct: 442 TATVYIEVEDENDNYPQFSEQNYVVQVPEDVGL--NTAVLRVQATDRDQGQNAAIHYSIL 499 Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIRDVN 251 GN QF + SLSG + ++ LD+E V+ Y L I+AQDGG P N++ ++ + + DVN Sbjct: 500 SGNVAGQFYLHSLSGILDVINPLDFEDVQKYSLSIKAQDGGRPPLINSSGVVSVQVLDVN 559 Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD------------- 298 DN P F +S FQ +V ENVP+GY +V +QA DAD G NA L Y + D Sbjct: 560 DNEPIFVSSPFQATVLENVPLGYPVVHIQAVDADSGENARLHYRLVDTASTFLGGGSAGP 619 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358 K+ D P I SGW+ +LDRE Y V A D G PP S++ + Sbjct: 620 KNPAPTPDFPFQIHNSSGWITVCAELDREEVEHYSFGVEAVDHGSPPMSSSTSVSITVLD 679 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQN 418 F YE+ L ED G+ V+TL A D D ++ + Y++TGGNTR RF+++SQ Sbjct: 680 VNDNDPVFTQPTYELRLNEDAAVGSSVLTLQARDRDANSVITYQLTGGNTRNRFALSSQR 739 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASV 478 G GLIT+A PLD+KQE++YVL V+A+D G RS TA V IN+TDAN + PVF+++ YT SV Sbjct: 740 GGGLITLALPLDYKQEQQYVLAVTASD-GTRSHTAHVLINVTDANTHRPVFQSSHYTVSV 798 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 ED P+GT++ +SA D D G NA+ITY + + QF I+P +G + T Sbjct: 799 SEDRPVGTSIATLSANDEDTGENARITYVIQDPVP---------QFRIDPDSGTMYTMME 849 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 LD E Y LT+ A+D G+P SDTT +EI ++D NDN P F Y +I EDA T Sbjct: 850 LDYENQVAYTLTIMAQDNGIPQKSDTTTLEILILDANDNAPQFLWDFYQGSIFEDAPPST 909 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 S+ QV ATD D G NGR+ Y D +G F I+P SGVIRT + LDRE+VA ++L A+ Sbjct: 910 SILQVSATDRDSGPNGRLLYTFQGGDDGDGDFYIEPTSGVIRTQRRLDRENVAVYNLWAL 969 Query: 659 AIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A+D G+P P S++V + + I DIND+ P+FE D L ++ EN+P+G+ + +IRA+DPDEG Sbjct: 970 AVDRGSPTPLSASVEIQVTILDINDNAPMFEKDELELFVEENNPVGSVVAKIRANDPDEG 1029 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND 777 PNA + Y I GD + F L+ G +L MV+LD+E R++Y LV++A S PL + Sbjct: 1030 PNAQIMYQIVEGDMRHFFQLDLLNG----DLRAMVELDFEV-RREYVLVVQATSAPLVSR 1084 Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNY----KDCFPVGPFGRVPAYDADVTDKLQYRILS 833 V IL+ D NDN PV+ DFQI+FNNY + FP G G +PA+D DV+D L Y + Sbjct: 1085 ATVHILLVDQNDNPPVLPDFQILFNNYVTNKSNSFPTGVIGCIPAHDPDVSDSLNYTFVQ 1144 Query: 834 GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLL 893 GN L+LL+ TG + LS L+ N P A MEVSV+DG++ + A L V +IT++ML Sbjct: 1145 GNELRLLLLDPATGELQLSRDLDNNRPLEALMEVSVSDGIHSVTAFCTLRVTIITDDMLT 1204 Query: 894 NSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSA 953 NSITVRL +M+ E+FLSPLL F++G+AA++ K+++++F+VQ+DTDV+ NILNV+FSA Sbjct: 1205 NSITVRLENMSQEKFLSPLLALFVEGVAAVLSTTKDDVFVFNVQNDTDVSSNILNVTFSA 1264 Query: 954 RRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEEC 1013 P GV G + L+E++YL+RT L ++T +VLPFDDNIC+ EPC N+ +C Sbjct: 1265 LLPG---GVRGQ---FFPSEDLQEQIYLNRTLLTTISTQRVLPFDDNICLREPCENYMKC 1318 Query: 1014 LTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSIC 1073 ++VL+F +++ F++S +VLFRPI+P+ C+CP GFTG CET + + G C Sbjct: 1319 VSVLRFDSSAPFLSSTTVLFRPIHPINGLRCRCPPGFTGDYCETEIDLCYSDPCGANGRC 1378 Query: 1074 RSGSQCVARREGGILCQGCSIDAAYTTAVCELRARS 1109 RS REGG C+ C D +T CE+ ARS Sbjct: 1379 RS-------REGGYTCE-CFED--FTGEHCEVDARS 1404 Score = 591 bits (1460), Expect = e-167 Identities = 319/903 (35%), Positives = 479/903 (53%), Gaps = 84/903 (9%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 +TC+C E FTG +CE C +C++G CV GG C C Y Sbjct: 1385 YTCECFEDFTGEHCEVDARSGRCA----NGVCKNGGTCVNLLIGGFHCV-CP-PGEYERP 1438 Query: 1102 VCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVS 1161 CE+ RSFP SF+TF GL++R + L FATQ +GLLLYNGR+NE+HDF+ALE+V Sbjct: 1439 YCEVTTRSFPPQSFVTFRGLRQRFHFTISLTFATQERNGLLLYNGRFNEKHDFIALEIVD 1498 Query: 1162 SEAGRGGGPGLRFSFSLGGGKSEIT--VEGNVGDGSWHTVEIEYFNRT------------ 1207 + ++ +FS G + + V V DG WH+V+++Y+N+ Sbjct: 1499 EQ--------VQLTFSAGETTTTVAPKVPSGVSDGRWHSVQVQYYNKPNIGHLGLPHGPS 1550 Query: 1208 ----ITMILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTET-CHRFLDLTGPL 1262 + +DDCD +++ D G Y+CA T+T + LDLTGPL Sbjct: 1551 GEKMAVVTVDDCDTTMAVRFGKDIG-NYSCA-----------AQGTQTGSKKSLDLTGPL 1598 Query: 1263 QIGGLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPC 1322 +GG+PN+P F V N+ FVGC+ + +D K +D+ ++A+NGT GC +R+ C C Sbjct: 1599 LLGGVPNLPEDFPVHNRQFVGCMRNLSVDGKNVDMAGFIANNGTREGCAARRNFCDGRRC 1658 Query: 1323 YNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLRPIQLPWLNALS 1382 NG C + W+ Y+C+C GK+C + P F G+ ++S++ L I +PW L Sbjct: 1659 QNGGTCVNRWNMYLCECPLRFGGKNCEQAMPHPQLFSGESVVSWSDLNIIISVPWYLGLM 1718 Query: 1383 IRTRQRDAFVMS----------IQLKSGLLHYSYNG-----ETMYLPMATLSDGAWHR-- 1425 RTR+ D+ +M +Q+ + L + + E++ L ++DG WH Sbjct: 1719 FRTRKEDSVLMEATSGGPTSFRLQILNNYLQFEVSHGPSDVESVMLSGLRVTDGEWHHLL 1778 Query: 1426 IEIKWLGTD------ISVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGLLASDV 1479 IE+K + D +++T+DYG+ + + G + +++GG + Sbjct: 1779 IELKNVKEDSEMKHLVTMTLDYGMDQNKAD-IGGMLPGLTVRSVVVGGASEDKVSVRRG- 1836 Query: 1480 GFFEGCIQDVRIG---TAQSLLN-RPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSS 1535 F GC+Q VR+G T + LN ++ V+DGC C S CPP S+C +W+ Sbjct: 1837 --FRGCMQGVRMGGTPTNVATLNMNNALKVRVKDGCDVDDPCTSSPCPPNSRCHDAWEDY 1894 Query: 1536 TCTCEAGRVGPQCVSACELGPC-GAARCVPDQ-TPKGYSCACEPGYTLTTSGCIESGKEE 1593 +C C+ G +G CV AC L PC CV +P+GY C C P + C Sbjct: 1895 SCVCDKGYLGINCVDACHLNPCENMGACVRSPGSPQGYVCECGPSHY--GPYCENKLDLP 1952 Query: 1594 CPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSEN 1653 CP GWWG CGPC C V++G+ P CNK NG+C CKEN+YK CLPC C+ GS + Sbjct: 1953 CPRGWWGNPVCGPCHCAVSKGFDPDCNKTNGQCQCKENYYKLLAQDTCLPCDCFPHGSHS 2012 Query: 1654 SSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFG 1713 +C+ ATGQC C+PGVIGR C+ C N +AEVT GCEV+Y+GCP++F G+WWP+TKFG Sbjct: 2013 RTCDMATGQCACKPGVIGRQCNRCDNPFAEVT-TLGCEVIYNGCPKAFEAGIWWPQTKFG 2071 Query: 1714 VETITDCPPGSSGRATRTCDETKDVPWQDPDMFNCTTATFYQLRKQLHKIETGELTMNTF 1773 CP GS G A R C K W P++FNCTT +F LR K+ E ++ Sbjct: 2072 QPAAVPCPKGSVGNAVRHCSGEKG--WLPPELFNCTTISFVDLRAMNEKLSRNETQVDGA 2129 Query: 1774 VGVRVAADLSTACANTPRLYGADVVVAEGILLELMDYELRQAGLNLTHSQDKDYVRNLLK 1833 +++ L +A +T L+G DV A +L ++ +E Q G +L +QD D+ +++ Sbjct: 2130 RALQLVRALRSATQHTGTLFGNDVRTAYQLLGHVLQHESWQQGFDLAATQDADFHEDVIH 2189 Query: 1834 STNTILNVEYEREWKRIRELTGHGAELLVQKFDEYIAVLAESQHDTYTSPFEIVTKDVVI 1893 S + +L W++I+ G A+LL ++ + Y + +A + TY PF IVT ++++ Sbjct: 2190 SGSALLAPATRAAWEQIQRSEGGTAQLL-RRLEGYFSNVARNVRRTYLRPFVIVTANMIL 2248 Query: 1894 SVD 1896 +VD Sbjct: 2249 AVD 2251 Score = 348 bits (856), Expect = 1e-93 Identities = 278/877 (31%), Positives = 418/877 (47%), Gaps = 73/877 (8%) Query: 23 FEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXX 82 F M Y+ ++ E +GT +L L A G+ V Y +E L E + Sbjct: 245 FPMPNYQVALFENEPAGTLILQLHAHYTIEGEEERVSYYME-----GLFDERS------- 292 Query: 83 XXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIID 142 + FRID +GA+ T + LDRE + + VKA D ++P S+T I V + D Sbjct: 293 ----RGYFRIDSATGAVSTDSVLDRETKETHVLRVKAVDYSTPPR---SATTYITVLVKD 345 Query: 143 DNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI 202 ND+ P F + Y V E++ V + I+A+D D N+ +RY ++GG + F + Sbjct: 346 TNDHSPVFEQSEYRERVRENLEV--GYEVLTIRASDRDSPINANLRYRVLGGAWDV-FQL 402 Query: 203 DSLSGDVSLVKTLDYEQVRSYRLVIRAQD-GGSPS-RSNTTQLLINIRDVNDNAPRFYTS 260 + SG VS LD E+ Y+L++ A D G +P S T + I + D NDN P+F Sbjct: 403 NESSGVVSTRAVLDREEAAEYQLLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQ 462 Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT 320 + V E+V + +++RVQA D D+G NA + Y++ +GNV + SG + Sbjct: 463 NYVVQVPEDVGLNTAVLRVQATDRDQGQNAAIHYSI----LSGNVAGQFYLHSLSGILDV 518 Query: 321 SGQLDRETQAKYQLLVTATDGGDPPR-SATATXXXXXXXXXXXXXXFMPGQYEVELAEDE 379 LD E KY L + A DGG PP +++ F+ ++ + E+ Sbjct: 519 INPLDFEDVQKYSLSIKAQDGGRPPLINSSGVVSVQVLDVNDNEPIFVSSPFQATVLENV 578 Query: 380 PPGTPVVTLTATDAD--EDNRLHYEIT-------GGNTRG--------RFSITSQNGRGL 422 P G PVV + A DAD E+ RLHY + GG + G F N G Sbjct: 579 PLGYPVVHIQAVDADSGENARLHYRLVDTASTFLGGGSAGPKNPAPTPDFPFQIHNSSGW 638 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480 ITV LD ++ Y V A D G S + V I + D N+ PVF Y + E Sbjct: 639 ITVCAELDREEVEHYSFGVEAVDHGSPPMSSSTSVSITVLDVNDNDPVFTQPTYELRLNE 698 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 DA +G++VL + A D D N+ ITY L+ + A Q+ G IT LD Sbjct: 699 DAAVGSSVLTLQARDRDA--NSVITYQLTGGNTRNRFALSSQR-----GGGLITLALPLD 751 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 + Y+L VTA DG + S T V I+V D N + PVF+ YT ++ ED VGTS+ Sbjct: 752 YKQEQQYVLAVTASDG---TRSHTAHVLINVTDANTHRPVFQSSHYTVSVSEDRPVGTSI 808 Query: 601 SQVGATDADVGLNGRIHYEL-DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 + + A D D G N RI Y + DP + F IDP SG + T LD E+ + L +A Sbjct: 809 ATLSANDEDTGENARITYVIQDPVPQ----FRIDPDSGTMYTMMELDYENQVAYTLTIMA 864 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 D G P +S T + I I D ND+ P F D I E++P T+I ++ A D D GPN Sbjct: 865 QDNGIPQKSDTTTLEILILDANDNAPQFLWDFYQGSIFEDAPPSTSILQVSATDRDSGPN 924 Query: 720 AVVHYSIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP-PLWND 777 + Y+ +GGDD + F +E G + + +D + + + L + SP PL Sbjct: 925 GRLLYTFQGGDDGDGDFYIEPTSGVIRTQ--RRLDRENVAVYNLWALAVDRGSPTPLSAS 982 Query: 778 VRVEILVTDVNDNAPVM-KDFQIIFNNYKDCFPVGP-FGRVPAYDAD--VTDKLQYRILS 833 V +++ + D+NDNAP+ KD +F ++ PVG ++ A D D ++ Y+I+ Sbjct: 983 VEIQVTILDINDNAPMFEKDELELF--VEENNPVGSVVAKIRANDPDEGPNAQIMYQIVE 1040 Query: 834 GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVT 870 G+ + L+ G + +L+ V + + V T Sbjct: 1041 GDMRHFFQLDLLNGDLRAMVELDFEVRREYVLVVQAT 1077 Score = 310 bits (761), Expect = 4e-82 Identities = 246/776 (31%), Positives = 379/776 (48%), Gaps = 78/776 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+ P F Q Y V E T VL ++ATD+D G+NA + Y+I Sbjct: 447 IEVEDENDNYPQFSEQNYVVQVPEDVGLNTAVLRVQATDRDQGQNAAIHYSI-------- 498 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 V F + SG L LD E V +Y++ +KA D P + Sbjct: 499 -----------LSGNVAGQFYLHSLSGILDVINPLDFEDVQKYSLSIKAQDGGRP--PLI 545 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +S+ + V ++D NDN P F + +V E++ + PV+ I+A DAD G N+ + Y Sbjct: 546 NSSGVVSVQVLDVNDNEPIFVSSPFQATVLENVPL-GYPVV-HIQAVDADSGENARLHYR 603 Query: 191 II-------GGNT----------QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233 ++ GG + F I + SG +++ LD E+V Y + A D G Sbjct: 604 LVDTASTFLGGGSAGPKNPAPTPDFPFQIHNSSGWITVCAELDREEVEHYSFGVEAVDHG 663 Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293 SP S++T + I + DVNDN P F ++ ++E+ +G S++ +QA D D N+ +T Sbjct: 664 SPPMSSSTSVSITVLDVNDNDPVFTQPTYELRLNEDAAVGSSVLTLQARDRD--ANSVIT 721 Query: 294 YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353 Y +T + T N ++ G + + LD + + +Y L VTA+DG RS TA Sbjct: 722 YQLTGGN-TRN-RFALSSQRGGGLITLALPLDYKQEQQYVLAVTASDG---TRSHTAHVL 776 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGR 411 F Y V ++ED P GT + TL+A D D E+ R+ Y I + + Sbjct: 777 INVTDANTHRPVFQSSHYTVSVSEDRPVGTSIATLSANDEDTGENARITYVIQ--DPVPQ 834 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVF 469 F I +G + T+ + LD++ + Y LT+ A D+G +SDT ++I I DAN+ AP F Sbjct: 835 FRIDPDSGT-MYTMME-LDYENQVAYTLTIMAQDNGIPQKSDTTTLEILILDANDNAPQF 892 Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 Y S+FEDAP T++L VSATD D G N ++ Y+ D F I P Sbjct: 893 LWDFYQGSIFEDAPPSTSILQVSATDRDSGPNGRLLYTFQGGDDG------DGDFYIEPT 946 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTA 588 +G I T + LDRE ++ Y L A D G P+ LS + +++++++D+NDN P+F++ Sbjct: 947 SGVIRTQRRLDRENVAVYNLWALAVDRGSPTPLSASVEIQVTILDINDNAPMFEKDELEL 1006 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648 + E+ VG+ V+++ A D D G N +I Y++ D F +D +G +R LD E Sbjct: 1007 FVEENNPVGSVVAKIRANDPDEGPNAQIMYQIVEGDMRH-FFQLDLLNGDLRAMVELDFE 1065 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF--YISENS---PIG 703 + + + + P S VHI + D ND+PPV + F Y++ S P G Sbjct: 1066 VRREY---VLVVQATSAPLVSRATVHILLVDQNDNPPVLPDFQILFNNYVTNKSNSFPTG 1122 Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759 IG I AHDPD + ++Y+ G++ L+ G EL DLD P Sbjct: 1123 -VIGCIPAHDPDVSDS--LNYTFVQGNELRLLLLDPATG----ELQLSRDLDNNRP 1171 Score = 289 bits (708), Expect = 1e-75 Identities = 219/683 (32%), Positives = 332/683 (48%), Gaps = 46/683 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND+ P+F ++A+V E G V+ ++A D D G+NA + Y + + L Sbjct: 553 VQVLDVNDNEPIFVSSPFQATVLENVPLGYPVVHIQAVDADSGENARLHYRLVDTASTFL 612 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 A F+I SG + A LDRE+V Y+ V+A D SP + Sbjct: 613 GGGSAGPKNPAPTPDFP--FQIHNSSGWITVCAELDREEVEHYSFGVEAVDHGSP---PM 667 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SS+ ++ + ++D NDN P F++ TY + ++ED +V + + ++A D D ANS I Y Sbjct: 668 SSSTSVSITVLDVNDNDPVFTQPTYELRLNEDAAVGSS--VLTLQARDRD--ANSVITYQ 723 Query: 191 IIGGNTQMQFSIDSLSGD--VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 + GGNT+ +F++ S G ++L LDY+Q + Y L + A DG +RS+T +LIN+ Sbjct: 724 LTGGNTRNRFALSSQRGGGLITLALPLDYKQEQQYVLAVTASDG---TRSHTAHVLINVT 780 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D N + P F +S + SVSE+ P+G SI + A D D G NA +TY + D +P Sbjct: 781 DANTHRPVFQSSHYTVSVSEDRPVGTSIATLSANDEDTGENARITYVIQD-------PVP 833 Query: 309 -ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 IDP SG +YT +LD E Q Y L + A D G P +S T T F+ Sbjct: 834 QFRIDPDSGTMYTMMELDYENQVAYTLTIMAQDNGIPQKSDTTTLEILILDANDNAPQFL 893 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNT-RGRFSITSQNGRGLIT 424 Y+ + ED PP T ++ ++ATD D + RL Y GG+ G F I + G+I Sbjct: 894 WDFYQGSIFEDAPPSTSILQVSATDRDSGPNGRLLYTFQGGDDGDGDFYIEPTS--GVIR 951 Query: 425 VAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFED 481 + LD + Y L A D G S + +Q+ I D N+ AP+FE V E+ Sbjct: 952 TQRRLDRENVAVYNLWALAVDRGSPTPLSASVEIQVTILDINDNAPMFEKDELELFVEEN 1011 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 P+G+ V + A D D G NAQI Y +I + H Q ++N A+ LD Sbjct: 1012 NPVGSVVAKIRANDPDEGPNAQIMY----QIVEGDMRHFFQLDLLNGDLRAMVE---LDF 1064 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ-QLYTANIMEDALVGTSV 600 E Y+L V A P +S T V I +VD NDN PV Q+ N + + Sbjct: 1065 EVRREYVLVVQAT--SAPLVSRAT-VHILLVDQNDNPPVLPDFQILFNNYVTNKSNSFPT 1121 Query: 601 SQVGATDA-DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 +G A D ++ ++Y + E ++DPA+G ++ ++ LD L V+ Sbjct: 1122 GVIGCIPAHDPDVSDSLNYTF-VQGNELRLLLLDPATGELQLSRDLDNNR-PLEALMEVS 1179 Query: 660 IDGGTPPQSSTVIVHIKIEDIND 682 + G S T +++ I D Sbjct: 1180 VSDGI--HSVTAFCTLRVTIITD 1200 Score = 177 bits (430), Expect = 5e-42 Identities = 139/457 (30%), Positives = 208/457 (45%), Gaps = 38/457 (8%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 H INV D N H PVF+ Y SV E GT++ TL A D+D G+NA + Y I+ Sbjct: 774 HVLINVTDANTHRPVFQSSHYTVSVSEDRPVGTSIATLSANDEDTGENARITYVIQ---- 829 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 D + P+ FRID SG + T LD E YT+ + A D P Sbjct: 830 DPV-PQ----------------FRIDPDSGTMYTMMELDYENQVAYTLTIMAQDNGIP-- 870 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 + S T T+ + I+D NDN PQF Y S+ ED + + I ++ ATD D G N + Sbjct: 871 -QKSDTTTLEILILDANDNAPQFLWDFYQGSIFEDAPPSTS--ILQVSATDRDSGPNGRL 927 Query: 188 RYAIIGGNT-QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLI 245 Y GG+ F I+ SG + + LD E V Y L A D GSP+ S + ++ + Sbjct: 928 LYTFQGGDDGDGDFYIEPTSGVIRTQRRLDRENVAVYNLWALAVDRGSPTPLSASVEIQV 987 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 I D+NDNAP F + V EN P+G + +++A D DEG NA++ Y + + G++ Sbjct: 988 TILDINDNAPMFEKDELELFVEENNPVGSVVAKIRANDPDEGPNAQIMYQIVE----GDM 1043 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 +D +G + +LD E + +Y L+V AT R+ Sbjct: 1044 RHFFQLDLLNGDLRAMVELDFEVRREYVLVVQATSAPLVSRATVHILLVDQNDNPPVLPD 1103 Query: 366 F--MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423 F + Y + P G + + A D D + L+Y GN + G + Sbjct: 1104 FQILFNNYVTNKSNSFPTGV-IGCIPAHDPDVSDSLNYTFVQGNELRLLLLDPATGE--L 1160 Query: 424 TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT 460 +++ LD + ++ VS +D G S TA + +T Sbjct: 1161 QLSRDLDNNRPLEALMEVSVSD-GIHSVTAFCTLRVT 1196 Score = 112 bits (270), Expect = 1e-22 Identities = 91/301 (30%), Positives = 136/301 (45%), Gaps = 15/301 (4%) Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP--KDREEGSFVIDPASGV 638 F Y + E+ GT + Q+ A G R+ Y ++ +R G F ID A+G Sbjct: 245 FPMPNYQVALFENEPAGTLILQLHAHYTIEGEEERVSYYMEGLFDERSRGYFRIDSATGA 304 Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698 + T+ LDRE+ TH L+ A+D TPP+S+T + + ++D ND PVFE + E Sbjct: 305 VSTDSVLDRETKETHVLRVKAVDYSTPPRSATTYITVLVKDTNDHSPVFEQSEYRERVRE 364 Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758 N +G + IRA D D NA + Y + GG + F L G + T LD E Sbjct: 365 NLEVGYEVLTIRASDRDSPINANLRYRVLGG-AWDVFQLNESSG----VVSTRAVLDREE 419 Query: 759 PRKKYELVIRA----ASP-PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF 813 +Y+L++ A +P PL V I V D NDN P + + +D Sbjct: 420 -AAEYQLLVEANDQGRNPGPLSATATVYIEVEDENDNYPQFSEQNYVVQVPEDVGLNTAV 478 Query: 814 GRVPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 RV A D D + Y ILSGN A L+ +G + + L+ + ++ + D Sbjct: 479 LRVQATDRDQGQNAAIHYSILSGNVAGQFYLHSLSGILDVINPLDFEDVQKYSLSIKAQD 538 Query: 872 G 872 G Sbjct: 539 G 539 Score = 68.5 bits (160), Expect = 2e-09 Identities = 47/151 (31%), Positives = 78/151 (51%), Gaps = 14/151 (9%) Query: 2173 GIRLKKPIRLQIWLDINRETFGSRTNPQCVHWS---TLRGSGEWSRVGCHTEIDYDWSPY 2229 G L +P+ + ++ RT P CV W+ + G+G WS GC Sbjct: 2383 GAPLPRPLERPVLVEFALLEVEERTKPVCVFWNHSLAVGGTGGWSARGCEL--------L 2434 Query: 2230 SEEPLLINCTCNHLSTFAVLVDEVDVEFIPEPSLLESVTSYTAFSISLPLLLTSWAALCL 2289 S + C C+H ++FAVL+D + E L+ VT Y A S+SL LL ++ L L Sbjct: 2435 SRNRTHVACQCSHTASFAVLMD-ISRRENGEVLPLKIVT-YAAVSLSLAALLVAFVLLSL 2492 Query: 2290 IRGGAATVSNSIHKHLIFSVFMAELLYLIAL 2320 +R + + +SIHKHL ++F+++L+++I + Sbjct: 2493 VRMLRSNL-HSIHKHLAVALFLSQLVFVIGI 2522 >UniRef50_Q9NYQ7 Cluster: Cadherin EGF LAG seven-pass G-type receptor 3 precursor; n=60; Eukaryota|Rep: Cadherin EGF LAG seven-pass G-type receptor 3 precursor - Homo sapiens (Human) Length = 3312 Score = 903 bits (2234), Expect = 0.0 Identities = 477/1085 (43%), Positives = 665/1085 (61%), Gaps = 52/1085 (4%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D NDHSPVFE QY ++RE G +L L+ATD D NA + Y + Sbjct: 421 VTVADRNDHSPVFEQAQYRETLRENVEEGYPILQLRATDGDAPPNANLRYRF-------V 473 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P A F ID RSG + T +DRE + Y ++V+A+DQ R Sbjct: 474 GPPAARAAAAAA-------FEIDPRSGLISTSGRVDREHMESYELVVEASDQGQEPGPR- 525 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+T +H+ ++D+NDN PQFSEK Y V ED V + V+ ++ ATD D AN + Y Sbjct: 526 SATVRVHITVLDENDNAPQFSEKRYVAQVRED--VRPHTVVLRVTATDRDKDANGLVHYN 583 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIRD 249 II GN++ F+IDSL+G++ +V LD+E R Y L IRAQD G P SN T L I + D Sbjct: 584 IISGNSRGHFAIDSLTGEIQVVAPLDFEAEREYALRIRAQDAGRPPLSNNTGLASIQVVD 643 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 +ND+ P F ++ FQ SV EN P+G+S++ +QA DAD G NA L Y++T D P Sbjct: 644 INDHIPIFVSTPFQVSVLENAPLGHSVIHIQAVDADHGENARLEYSLTGVA----PDTPF 699 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 I+ +GWV SG LDRE+ Y V A D G PP SA+A+ F Sbjct: 700 VINSATGWVSVSGPLDRESVEHYFFGVEARDHGSPPLSASASVTVTVLDVNDNRPEFTMK 759 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 +Y + L ED GT VV++TA D D ++ + Y+ITGGNTR RF+I++Q G GL+T+A PL Sbjct: 760 EYHLRLNEDAAVGTSVVSVTAVDRDANSAISYQITGGNTRNRFAISTQGGVGLVTLALPL 819 Query: 430 DFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 D+KQER + L ++A+D D V INITDAN + PVF++A Y+ SV ED P+G+T++ Sbjct: 820 DYKQERYFKLVLTASDRA-LHDHCYVHINITDANTHRPVFQSAHYSVSVNEDRPMGSTIV 878 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 V+SA+D DVG NA+ITY L + QF I+ +GAIT LD E Y L Sbjct: 879 VISASDDDVGENARITYLLEDNLP---------QFRIDADSGAITLQAPLDYEDQVTYTL 929 Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 +TARD G+P +DTT VE+ V DVNDN P F YT + EDA TSV Q+ ATD D Sbjct: 930 AITARDNGIPQKADTTYVEVMVNDVNDNAPQFVASHYTGLVSEDAPPFTSVLQISATDRD 989 Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669 NGR+ Y + +G F I+P SG++RT + LDRE+V+ ++L A A+D G PP + Sbjct: 990 AHANGRVQYTFQNGEDGDGDFTIEPTSGIVRTVRRLDREAVSVYELTAYAVDRGVPPLRT 1049 Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729 V + + ++D+ND+ PVF ++ + ENS +G+ + +I A DPDEGPNA + Y I G Sbjct: 1050 PVSIQVMVQDVNDNAPVFPAEEFEVRVKENSIVGSVVAQITAVDPDEGPNAHIMYQIVEG 1109 Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVND 789 + F ++ G EL ++DLDYE+ R++Y +V++A S PL + V + + D ND Sbjct: 1110 NIPELFQMDIFSG----ELTALIDLDYEA-RQEYVIVVQATSAPLVSRATVHVRLVDQND 1164 Query: 790 NAPVMKDFQIIFNNY----KDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNET 845 N+PV+ +FQI+FNNY D FP G GR+PAYD DV+D L Y GN L+++N+T Sbjct: 1165 NSPVLNNFQILFNNYVSNRSDTFPSGIIGRIPAYDPDVSDHLFYSFERGNELQLLVVNQT 1224 Query: 846 TGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTA 905 +G + LS +L+ N P +A+M V+VTDG++ + A L V +ITEE+L NS+TVRL +M Sbjct: 1225 SGELRLSRKLDNNRPLVASMLVTVTDGLHSVTAQCVLRVVIITEELLANSLTVRLENMWQ 1284 Query: 906 EQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRP-DAEVGVAG 964 E+FLSPLLG F++G+AA++ P E+++IF++Q+DTDV G +LNVSFSA P A G AG Sbjct: 1285 ERFLSPLLGRFLEGVAAVLATPAEDVFIFNIQNDTDVGGTVLNVSFSALAPRGAGAGAAG 1344 Query: 965 DPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASG 1024 P +S L+E++Y+ R LA + + VLPFDDN+C+ EPC N+ +C++VL+F +++ Sbjct: 1345 ---PWFSSEELQEQLYVRRAALAARSLLDVLPFDDNVCLREPCENYMKCVSVLRFDSSAP 1401 Query: 1025 FVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARRE 1084 F+ S S LFRPI P+ C+CP GFTG CET L + CR+G C ARRE Sbjct: 1402 FLASASTLFRPIQPIAGLRCRCPPGFTGDFCETELDLCY------SNPCRNGGAC-ARRE 1454 Query: 1085 GGILC 1089 GG C Sbjct: 1455 GGYTC 1459 Score = 628 bits (1551), Expect = e-178 Identities = 348/912 (38%), Positives = 488/912 (53%), Gaps = 84/912 (9%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 +TC C FTG +CE C V G +CR+G C GG CQ C A+ Sbjct: 1457 YTCVCRPRFTGEDCELDTEAGRC-VPG---VCRNGGTCTDAPNGGFRCQ-CPAGGAFEGP 1511 Query: 1102 VCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVS 1161 CE+ ARSFP SSF+ F GL++R + L L FAT SGLL YNGR NE+HDFLALELV+ Sbjct: 1512 RCEVAARSFPPSSFVMFRGLRQRFHLTLSLSFATVQQSGLLFYNGRLNEKHDFLALELVA 1571 Query: 1162 SEAGRGGGPGLRFSFSLGGGKSEI--TVEGNVGDGSWHTVEIEYFNRTIT---------- 1209 + +R ++S G + + TV G + DG WHTV + Y+N+ T Sbjct: 1572 GQ--------VRLTYSTGESNTVVSPTVPGGLSDGQWHTVHLRYYNKPRTDALGGAQGPS 1623 Query: 1210 ------MILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQ 1263 + +DDCD ++L A+ G Y+C A + T + + LDLTGPL Sbjct: 1624 KDKVAVLSVDDCDVAVALQFGAEIG-NYSC---------AAAGVQTSS-KKSLDLTGPLL 1672 Query: 1264 IGGLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCY 1323 +GG+PN+P +F V +KDF+GC+ D +ID + +D+ ++VA+NGT+AGC K C S PC Sbjct: 1673 LGGVPNLPENFPVSHKDFIGCMRDLHIDGRRVDMAAFVANNGTMAGCQAKLHFCDSGPCK 1732 Query: 1324 NGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFN-PLLRPIQLPWLNALS 1382 N CS+ W ++ CDC G GKDC + P F G+G LS+N + +PW L+ Sbjct: 1733 NSGFCSERWGSFSCDCPVGFGGKDCQLTMAHPHHFRGNGTLSWNFGSDMAVSVPWYLGLA 1792 Query: 1383 IRTRQRDAFVMSI----------QLKSGLLHY-----SYNGETMYLPMATLSDGAWH--R 1425 RTR +M + QL GLL S + L T+SDG WH R Sbjct: 1793 FRTRATQGVLMQVQAGPHSTLLCQLDRGLLSVTVTRGSGRASHLLLDQVTVSDGRWHDLR 1852 Query: 1426 IEIK-----WLGTDI-SVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGLLASDV 1479 +E++ G + V++D+ L M + +++QG + ++ +GGL + A Sbjct: 1853 LELQEEPGGRRGHHVLMVSLDFSLFQDTM-AVGSELQGLKVKQLHVGGLPPGSAEEAPQ- 1910 Query: 1480 GFFEGCIQDVRIGTAQS---LLNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSST 1536 G GCIQ V +G+ S L P+ R N GC C CPP++ C W + + Sbjct: 1911 GLV-GCIQGVWLGSTPSGSPALLPPSHRVNAEPGCVVTNACASGPCPPHADCRDLWQTFS 1969 Query: 1537 CTCEAGRVGPQCVSACELGPC---GAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKEE 1593 CTC+ G GP CV AC L PC G+ R +P P GY+C C GY C ++ Sbjct: 1970 CTCQPGYYGPGCVDACLLNPCQNQGSCRHLPG-APHGYTCDCVGGY--FGHHCEHRMDQQ 2026 Query: 1594 CPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSEN 1653 CP GWWG CGPC CDV +G+ P+CNK NG+CHCKE HY+P G+ CLPC CY GS + Sbjct: 2027 CPRGWWGSPTCGPCNCDVHKGFDPNCNKTNGQCHCKEFHYRPRGSDSCLPCDCYPVGSTS 2086 Query: 1654 SSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFG 1713 SC +GQC CRPG +GR C++C + +AEVT SGC V+YD CP+S GVWWP+TKFG Sbjct: 2087 RSCAPHSGQCPCRPGALGRQCNSCDSPFAEVTA-SGCRVLYDACPKSLRSGVWWPQTKFG 2145 Query: 1714 VETITDCPPGSSGRATRTCDETKDVPWQDPDMFNCTTATFYQLRKQLHKIETGELTMNTF 1773 V CP G+ G A R CDE + W +PD+FNCT+ F +L L +E + ++T Sbjct: 2146 VLATVPCPRGALGAAVRLCDEAQG--WLEPDLFNCTSPAFRELSLLLDGLELNKTALDTM 2203 Query: 1774 VGVRVAADLSTACANTPRLYGADVVVAEGILLELMDYELRQAGLNLTHSQDKDYVRNLLK 1833 ++A L +T + DV V +L L+ +E Q G LT +QD + NLL Sbjct: 2204 EAKKLAQRLREVTGHTDHYFSQDVRVTARLLAHLLAFESHQQGFGLTATQDAHFNENLLW 2263 Query: 1834 STNTILNVEYEREWKRIRELT---GHGAELLVQKFDEYIAVLAESQHDTYTSPFEIVTKD 1890 + + +L E W + + G+ LV+ +EY A LA + TY +P +VT + Sbjct: 2264 AGSALLAPETGDLWAALGQRAPGGSPGSAGLVRHLEEYAATLARNMELTYLNPMGLVTPN 2323 Query: 1891 VVISVDTVTSES 1902 +++S+D + S Sbjct: 2324 IMLSIDRMEHPS 2335 Score = 355 bits (872), Expect = 1e-95 Identities = 255/807 (31%), Positives = 390/807 (48%), Gaps = 42/807 (5%) Query: 145 DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY---AIIGGNTQMQFS 201 + +PQF + Y V E+ + + ++ A D D G + Y A++ + FS Sbjct: 320 NRHPQFPQYNYQTLVPENEAA--GTAVLRVVAQDPDAGEAGRLVYSLAALMNSRSLELFS 377 Query: 202 IDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261 ID SG + LD E + + L + AQD GSP S TT + + + D ND++P F + Sbjct: 378 IDPQSGLIRTAAALDRESMERHYLRVTAQDHGSPRLSATTMVAVTVADRNDHSPVFEQAQ 437 Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT-GNVDLPITIDPRSGWVYT 320 ++E++ ENV GY I++++A D D NA L Y IDPRSG + T Sbjct: 438 YRETLRENVEEGYPILQLRATDGDAPPNANLRYRFVGPPAARAAAAAAFEIDPRSGLIST 497 Query: 321 SGQLDRETQAKYQLLVTATD-GGDP-PRSATATXXXXXXXXXXXXXXFMPGQYEVELAED 378 SG++DRE Y+L+V A+D G +P PRSAT F +Y ++ ED Sbjct: 498 SGRVDREHMESYELVVEASDQGQEPGPRSATVRVHITVLDENDNAPQFSEKRYVAQVRED 557 Query: 379 EPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436 P T V+ +TATD D+D +HY I GN+RG F+I S G I V PLDF+ ER Sbjct: 558 VRPHTVVLRVTATDRDKDANGLVHYNIISGNSRGHFAIDSLTGE--IQVVAPLDFEAERE 615 Query: 437 YVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 Y L + A D+G ++T + I + D N++ P+F + P+ SV E+AP+G +V+ + A Sbjct: 616 YALRIRAQDAGRPPLSNNTGLASIQVVDINDHIPIFVSTPFQVSVLENAPLGHSVIHIQA 675 Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553 D+D G NA++ YSL+ VA D FVIN TG ++ + LDRE++ Y V A Sbjct: 676 VDADHGENARLEYSLT------GVA-PDTPFVINSATGWVSVSGPLDRESVEHYFFGVEA 728 Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613 RD G P LS + V ++V+DVNDN P F + Y + EDA VGTSV V A D D N Sbjct: 729 RDHGSPPLSASASVTVTVLDVNDNRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRDA--N 786 Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673 I Y++ F I GV AL + K V + V Sbjct: 787 SAISYQI-TGGNTRNRFAISTQGGVGLVTLALPLDYKQERYFKLV-LTASDRALHDHCYV 844 Query: 674 HIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN 733 HI I D N PVF+S + ++E+ P+G+TI I A D D G NA + Y ++ D+ Sbjct: 845 HINITDANTHRPVFQSAHYSVSVNEDRPMGSTIVVISASDDDVGENARITYLLE--DNLP 902 Query: 734 SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDN 790 F ++ +D + LDYE + Y L I A P + VE++V DVNDN Sbjct: 903 QFRID----ADSGAITLQAPLDYED-QVTYTLAITARDNGIPQKADTTYVEVMVNDVNDN 957 Query: 791 APVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNAN-LILLNETTG 847 AP +D P ++ A D D ++QY +G + + + T+G Sbjct: 958 APQFVASHYTGLVSEDAPPFTSVLQISATDRDAHANGRVQYTFQNGEDGDGDFTIEPTSG 1017 Query: 848 SMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAE 906 + +L+ + + D GV ++ +S++++ +++ N+ + Sbjct: 1018 IVRTVRRLDREAVSVYELTAYAVDRGVPPLRT--PVSIQVMVQDVNDNAPVFPAEEFEVR 1075 Query: 907 QFLSPLLGFFIDGLAAIIPCPKENIYI 933 + ++G + + A+ P N +I Sbjct: 1076 VKENSIVGSVVAQITAVDPDEGPNAHI 1102 Score = 343 bits (843), Expect = 4e-92 Identities = 272/912 (29%), Positives = 428/912 (46%), Gaps = 69/912 (7%) Query: 17 NDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAX 76 N H P F Y+ V E ++GT VL + A D D G+ + Y++ A +N Sbjct: 320 NRH-PQFPQYNYQTLVPENEAAGTAVLRVVAQDPDAGEAGRLVYSL----AALMNSRSL- 373 Query: 77 XXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATI 136 ++F ID +SG + T A+LDRE + R+ + V A D SP RLS+T + Sbjct: 374 -----------ELFSIDPQSGLIRTAAALDRESMERHYLRVTAQDHGSP---RLSATTMV 419 Query: 137 HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG--- 193 V + D ND+ P F + Y ++ E +V + I +++ATD D N+ +RY +G Sbjct: 420 AVTVADRNDHSPVFEQAQYRETLRE--NVEEGYPILQLRATDGDAPPNANLRYRFVGPPA 477 Query: 194 --GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQLLINIRD 249 F ID SG +S +D E + SY LV+ A D G RS T ++ I + D Sbjct: 478 ARAAAAAAFEIDPRSGLISTSGRVDREHMESYELVVEASDQGQEPGPRSATVRVHITVLD 537 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 NDNAP+F + V E+V ++RV A D D+ N + Y + +GN Sbjct: 538 ENDNAPQFSEKRYVAQVREDVRPHTVVLRVTATDRDKDANGLVHYNI----ISGNSRGHF 593 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRS-ATATXXXXXXXXXXXXXXFMP 368 ID +G + LD E + +Y L + A D G PP S T F+ Sbjct: 594 AIDSLTGEIQVVAPLDFEAEREYALRIRAQDAGRPPLSNNTGLASIQVVDINDHIPIFVS 653 Query: 369 GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 ++V + E+ P G V+ + A DAD E+ RL Y +TG F I S G ++V+ Sbjct: 654 TPFQVSVLENAPLGHSVIHIQAVDADHGENARLEYSLTGVAPDTPFVINS--ATGWVSVS 711 Query: 427 QPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 PLD + Y V A D G S +A V + + D N+ P F Y + EDA + Sbjct: 712 GPLDRESVEHYFFGVEARDHGSPPLSASASVTVTVLDVNDNRPEFTMKEYHLRLNEDAAV 771 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 GT+V+ V+A D D N+ I+Y ++ + A Q V G +T LD + Sbjct: 772 GTSVVSVTAVDRDA--NSAISYQITGGNTRNRFAISTQGGV-----GLVTLALPLDYKQE 824 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 + L +TA D +L D V I++ D N + PVF+ Y+ ++ ED +G+++ + Sbjct: 825 RYFKLVLTASD---RALHDHCYVHINITDANTHRPVFQSAHYSVSVNEDRPMGSTIVVIS 881 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 A+D DVG N RI Y L+ + F ID SG I LD E T+ L A D G Sbjct: 882 ASDDDVGENARITYLLEDNLPQ---FRIDADSGAITLQAPLDYEDQVTYTLAITARDNGI 938 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 P ++ T V + + D+ND+ P F + T +SE++P T++ +I A D D N V Y Sbjct: 939 PQKADTTYVEVMVNDVNDNAPQFVASHYTGLVSEDAPPFTSVLQISATDRDAHANGRVQY 998 Query: 725 SIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEIL 783 + + G+D + F++E G V +D + S + + PPL V ++++ Sbjct: 999 TFQNGEDGDGDFTIEPTSGI--VRTVRRLDREAVSVYELTAYAVDRGVPPLRTPVSIQVM 1056 Query: 784 VTDVNDNAPVM--KDFQIIFNNYKDCFPVGP-FGRVPAYDAD--VTDKLQYRILSGNNAN 838 V DVNDNAPV ++F++ K+ VG ++ A D D + Y+I+ GN Sbjct: 1057 VQDVNDNAPVFPAEEFEV---RVKENSIVGSVVAQITAVDPDEGPNAHIMYQIVEGNIPE 1113 Query: 839 LILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE---EMLLNS 895 L ++ +G +T L+ + + V T + + + VRL+ + +LN+ Sbjct: 1114 LFQMDIFSGELTALIDLDYEARQEYVIVVQATSA--PLVSRATVHVRLVDQNDNSPVLNN 1171 Query: 896 ITVRLNDMTAEQ 907 + N+ + + Sbjct: 1172 FQILFNNYVSNR 1183 Score = 309 bits (758), Expect = 9e-82 Identities = 227/734 (30%), Positives = 358/734 (48%), Gaps = 56/734 (7%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 + I VLD ND++P F ++Y A VRE T VL + ATD+D N V Y I ++ Sbjct: 529 VRVHITVLDENDNAPQFSEKRYVAQVREDVRPHTVVLRVTATDRDKDANGLVHYNI--IS 586 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 ++ + F ID +G + A LD E Y + ++A D P Sbjct: 587 GNS-----------------RGHFAIDSLTGEIQVVAPLDFEAEREYALRIRAQDAGRPP 629 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 ++T + ++D ND+ P F + VSV E+ + + + I+A DAD G N+ Sbjct: 630 LS--NNTGLASIQVVDINDHIPIFVSTPFQVSVLENAPLGHS--VIHIQAVDADHGENAR 685 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 + Y++ G F I+S +G VS+ LD E V Y + A+D GSP S + + + Sbjct: 686 LEYSLTGVAPDTPFVINSATGWVSVSGPLDRESVEHYFFGVEARDHGSPPLSASASVTVT 745 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + DVNDN P F + ++E+ +G S+V V A D D N+ ++Y +T + T N Sbjct: 746 VLDVNDNRPEFTMKEYHLRLNEDAAVGTSVVSVTAVDRD--ANSAISYQITGGN-TRN-R 801 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 I+ G V + LD + + ++L++TA+D F Sbjct: 802 FAISTQGGVGLVTLALPLDYKQERYFKLVLTASDRA---LHDHCYVHINITDANTHRPVF 858 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLIT 424 Y V + ED P G+ +V ++A+D D E+ R+ Y + + R S G IT Sbjct: 859 QSAHYSVSVNEDRPMGSTIVVISASDDDVGENARITYLLEDNLPQFRIDADS----GAIT 914 Query: 425 VAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 + PLD++ + Y L ++A D+G ++DT V++ + D N+ AP F + YT V EDA Sbjct: 915 LQAPLDYEDQVTYTLAITARDNGIPQKADTTYVEVMVNDVNDNAPQFVASHYTGLVSEDA 974 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 P T+VL +SATD D N ++ Y+ + D F I P +G + T + LDRE Sbjct: 975 PPFTSVLQISATDRDAHANGRVQYTFQNGEDG------DGDFTIEPTSGIVRTVRRLDRE 1028 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 +S Y LT A D GVP L +++ V DVNDN PVF + + + E+++VG+ V+Q Sbjct: 1029 AVSVYELTAYAVDRGVPPLRTPVSIQVMVQDVNDNAPVFPAEEFEVRVKENSIVGSVVAQ 1088 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 + A D D G N I Y++ + E F +D SG + LD E+ + + + Sbjct: 1089 ITAVDPDEGPNAHIMYQIVEGNIPE-LFQMDIFSGELTALIDLDYEARQEY---VIVVQA 1144 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTF--YISENS---PIGTTIGEIRAHDPDEG 717 + P S VH+++ D ND+ PV + + F Y+S S P G IG I A+DPD Sbjct: 1145 TSAPLVSRATVHVRLVDQNDNSPVLNNFQILFNNYVSNRSDTFPSG-IIGRIPAYDPDVS 1203 Query: 718 PNAVVHYSIKGGDD 731 + + YS + G++ Sbjct: 1204 DH--LFYSFERGNE 1215 Score = 271 bits (665), Expect = 2e-70 Identities = 202/648 (31%), Positives = 310/648 (47%), Gaps = 28/648 (4%) Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295 +R T+ R + P+F +Q V EN G +++RV A D D G L Y+ Sbjct: 304 ARKVTSANRARFRRAANRHPQFPQYNYQTLVPENEAAGTAVLRVVAQDPDAGEAGRLVYS 363 Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355 + + +++L +IDP+SG + T+ LDRE+ ++ L VTA D G P SAT Sbjct: 364 LAALMNSRSLEL-FSIDPQSGLIRTAAALDRESMERHYLRVTAQDHGSPRLSATTMVAVT 422 Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITG---GNTRG 410 F QY L E+ G P++ L ATD D + L Y G Sbjct: 423 VADRNDHSPVFEQAQYRETLRENVEEGYPILQLRATDGDAPPNANLRYRFVGPPAARAAA 482 Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS----GGRSDTAMVQINITDANNYA 466 + GLI+ + +D + Y L V A+D G RS T V I + D N+ A Sbjct: 483 AAAFEIDPRSGLISTSGRVDREHMESYELVVEASDQGQEPGPRSATVRVHITVLDENDNA 542 Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 P F Y A V ED T VL V+ATD D N + Y++ IS + H F I Sbjct: 543 PQFSEKRYVAQVREDVRPHTVVLRVTATDRDKDANGLVHYNI---ISGNSRGH----FAI 595 Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV-EISVVDVNDNEPVFKQQL 585 + TG I LD E Y L + A+D G P LS+ T + I VVD+ND+ P+F Sbjct: 596 DSLTGEIQVVAPLDFEAEREYALRIRAQDAGRPPLSNNTGLASIQVVDINDHIPIFVSTP 655 Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645 + +++E+A +G SV + A DAD G N R+ Y L + FVI+ A+G + + L Sbjct: 656 FQVSVLENAPLGHSVIHIQAVDADHGENARLEYSLTGV-APDTPFVINSATGWVSVSGPL 714 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 DRESV + A D G+PP S++ V + + D+ND+ P F ++E++ +GT+ Sbjct: 715 DRESVEHYFFGVEARDHGSPPLSASASVTVTVLDVNDNRPEFTMKEYHLRLNEDAAVGTS 774 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM-VDLDYESPRKKYE 764 + + A D D N+ + Y I GG+ N F++ T+ G LVT+ + LDY+ R ++ Sbjct: 775 VVSVTAVDRD--ANSAISYQITGGNTRNRFAISTQGG---VGLVTLALPLDYKQER-YFK 828 Query: 765 LVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADV 823 LV+ A+ L + V I +TD N + PV + + +D P+G + A D DV Sbjct: 829 LVLTASDRALHDHCYVHINITDANTHRPVFQSAHYSVSVNED-RPMGSTIVVISASDDDV 887 Query: 824 TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + + L +N ++ +G++TL L+ T+ ++ D Sbjct: 888 GENARITYLLEDNLPQFRIDADSGAITLQAPLDYEDQVTYTLAITARD 935 Score = 79.8 bits (188), Expect = 1e-12 Identities = 62/225 (27%), Positives = 102/225 (45%), Gaps = 29/225 (12%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 Q+ V D ND++PVF +++E V+E + G+ V + A D D G NA + Y I Sbjct: 1054 QVMVQDVNDNAPVFPAEEFEVRVKENSIVGSVVAQITAVDPDEGPNAHIMYQI------- 1106 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + ++F++D SG L LD E Y ++V+AT S Sbjct: 1107 ------------VEGNIPELFQMDIFSGELTALIDLDYEARQEYVIVVQAT------SAP 1148 Query: 130 LSSTATIHVNIIDDNDNYPQFS--EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 L S AT+HV ++D NDN P + + + V + +I +I A D DV + + Sbjct: 1149 LVSRATVHVRLVDQNDNSPVLNNFQILFNNYVSNRSDTFPSGIIGRIPAYDPDV--SDHL 1206 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232 Y+ GN ++ SG++ L + LD + +++ DG Sbjct: 1207 FYSFERGNELQLLVVNQTSGELRLSRKLDNNRPLVASMLVTVTDG 1251 Score = 37.9 bits (84), Expect = 4.0 Identities = 15/39 (38%), Positives = 19/39 (48%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C S PC NG C+ Y C C+ TG+DC Sbjct: 1432 CETELDLCYSNPCRNGGACARREGGYTCVCRPRFTGEDC 1470 Score = 37.9 bits (84), Expect = 4.0 Identities = 23/83 (27%), Positives = 44/83 (53%), Gaps = 1/83 (1%) Query: 2238 CTCNHLSTFAVLVDEVDVEFIPEPSLLESVTSYTAFSISLPLLLTSWAALCLIRGGAATV 2297 C C+ TF VL+D E + L +V ++ ++S+ L+ + A L +R + V Sbjct: 2512 CRCSRTGTFGVLMDASPRERLEGDLELLAVFTHVVVAVSVAALVLTAAILLSLRSLKSNV 2571 Query: 2298 SNSIHKHLIFSVFMAELLYLIAL 2320 IH ++ ++ +AELL+L+ + Sbjct: 2572 -RGIHANVAAALGVAELLFLLGI 2593 >UniRef50_Q9HCU4 Cluster: Cadherin EGF LAG seven-pass G-type receptor 2 precursor; n=38; Euteleostomi|Rep: Cadherin EGF LAG seven-pass G-type receptor 2 precursor - Homo sapiens (Human) Length = 2923 Score = 901 bits (2230), Expect = 0.0 Identities = 492/1105 (44%), Positives = 668/1105 (60%), Gaps = 58/1105 (5%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D NDH PVFE Q+Y+ S+RE G VLT++ATD D NA + Y L+ Sbjct: 277 ILVTDTNDHDPVFEQQEYKESLRENLEVGYEVLTVRATDGDAPPNANILY--RLLEGSGG 334 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +P + VF ID RSG + TR +DRE+V Y + V+A+DQ R Sbjct: 335 SPSE--------------VFEIDPRSGVIRTRGPVDREEVESYQLTVEASDQGRDPGPR- 379 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+TA + +++ DDNDN PQFSEK Y V V ED VT + ++ A+D D G+N+ + Y+ Sbjct: 380 STTAAVFLSVEDDNDNAPQFSEKRYVVQVRED--VTPGAPVLRVTASDRDKGSNAVVHYS 437 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIRD 249 I+ GN + QF +D+ +G + +V LDYE + Y L +RAQDGG P SN + L+ + + D Sbjct: 438 IMSGNARGQFYLDAQTGALDVVSPLDYETTKEYTLRVRAQDGGRPPLSNVSGLVTVQVLD 497 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 +NDNAP F ++ FQ +V E+VP+GY ++ VQA DAD G NA L Y + + D P Sbjct: 498 INDNAPIFVSTPFQATVLESVPLGYLVLHVQAIDADAGDNARLEYRLAGVGH----DFPF 553 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 TI+ +GW+ + +LDRE Y V A D G P +A+A+ F Sbjct: 554 TINNGTGWISVAAELDREEVDFYSFGVEARDHGTPALTASASVSVTVLDVNDNNPTFTQP 613 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 +Y V L ED GT VVT++A D D + + Y+IT GNTR RFSITSQ+G GL+++A PL Sbjct: 614 EYTVRLNEDAAVGTSVVTVSAVDRDAHSVITYQITSGNTRNRFSITSQSGGGLVSLALPL 673 Query: 430 DFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 D+K ER+YVL V+A+D G R DTA + +N+TDAN + PVF+++ YT +V ED P GTTV+ Sbjct: 674 DYKLERQYVLAVTASD-GTRQDTAQIVVNVTDANTHRPVFQSSHYTVNVNEDRPAGTTVV 732 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 ++SATD D G NA+ITY + I QF I+ TGA+TT LD E Y L Sbjct: 733 LISATDEDTGENARITYFMEDSIP---------QFRIDADTGAVTTQAELDYEDQVSYTL 783 Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 +TARD G+P SDTT +EI V DVNDN P F + Y ++ ED TSV Q+ ATD D Sbjct: 784 AITARDNGIPQKSDTTYLEILVNDVNDNAPQFLRDSYQGSVYEDVPPFTSVLQISATDRD 843 Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669 GLNGR+ Y D +G F+++ SG++RT + LDRE+VA + L+A A+D G PP + Sbjct: 844 SGLNGRVFYTFQGGDDGDGDFIVESTSGIVRTLRRLDRENVAQYVLRAYAVDKGMPPART 903 Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729 + V + + D+ND+PPVFE D ++ ENSPIG + + A DPDEG NA + Y I G Sbjct: 904 PMEVTVTVLDVNDNPPVFEQDEFDVFVEENSPIGLAVARVTATDPDEGTNAQIMYQIVEG 963 Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVND 789 + F L+ G EL +VDLDYE R +Y LVI+A S PL + V + + D ND Sbjct: 964 NIPEVFQLDIFSG----ELTALVDLDYED-RPEYVLVIQATSAPLVSRATVHVRLLDRND 1018 Query: 790 NAPVMKDFQIIFNNY----KDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNET 845 N PV+ +F+I+FNNY FP G GRVPA+D D++D L Y GN +L+LLN + Sbjct: 1019 NPPVLGNFEILFNNYVTNRSSSFPGGAIGRVPAHDPDISDSLTYSFERGNELSLVLLNAS 1078 Query: 846 TGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTA 905 TG + LS L+ N P A M V V+DGV+ + A L V +IT+EML +SIT+RL DM+ Sbjct: 1079 TGELKLSRALDNNRPLEAIMSVLVSDGVHSVTAQCALRVTIITDEMLTHSITLRLEDMSP 1138 Query: 906 EQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVT-GNILNVSFSARRPDAEVGVAG 964 E+FLSPLLG FI +AA + P +++ +F+VQ DTD G+ILNVS S +P G G Sbjct: 1139 ERFLSPLLGLFIQAVAATLATPPDHVVVFNVQRDTDAPGGHILNVSLSVGQPP---GPGG 1195 Query: 965 DPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASG 1024 P P L+ER+YL+R+ L ++ +VLPFDDNIC+ EPC N+ C++VL+F +++ Sbjct: 1196 GP-PFLPSEDLQERLYLNRSLLTAISAQRVLPFDDNICLREPCENYMRCVSVLRFDSSAP 1254 Query: 1025 FVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARRE 1084 F+ S SVLFRPI+PV C+CP GFTG CET + G CRS RE Sbjct: 1255 FIASSSVLFRPIHPVGGLRCRCPPGFTGDYCETEVDLCYSRPCGPHGRCRS-------RE 1307 Query: 1085 GGILCQGCSIDAAYTTAVCELRARS 1109 GG C C YT CE+ ARS Sbjct: 1308 GGYTCL-CR--DGYTGEHCEVSARS 1329 Score = 626 bits (1547), Expect = e-177 Identities = 337/941 (35%), Positives = 499/941 (53%), Gaps = 82/941 (8%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 +TC C +G+TG +CE C +C++G CV GG C S D + Sbjct: 1310 YTCLCRDGYTGEHCEVSARSGRCTP----GVCKNGGTCVNLLVGGFKCDCPSGD--FEKP 1363 Query: 1102 VCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVS 1161 C++ RSFP SF+TF GL++R L L FAT+ GLLLYNGR+NE+HDF+ALE++ Sbjct: 1364 YCQVTTRSFPAHSFITFRGLRQRFHFTLALSFATKERDGLLLYNGRFNEKHDFVALEVIQ 1423 Query: 1162 SEAGRGGGPGLRFSFSLGGGKSEIT--VEGNVGDGSWHTVEIEYFNRTI----------- 1208 + ++ +FS G + ++ V G V DG WHTV+++Y+N+ + Sbjct: 1424 EQ--------VQLTFSAGESTTTVSPFVPGGVSDGQWHTVQLKYYNKPLLGQTGLPQGPS 1475 Query: 1209 -----TMILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQ 1263 + +D CD ++L + G Y+CA + + LDLTGPL Sbjct: 1476 EQKVAVVTVDGCDTGVALRFGSVLG-NYSCA----------AQGTQGGSKKSLDLTGPLL 1524 Query: 1264 IGGLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCY 1323 +GG+P++P SF V+ + FVGC+ + +D + ID+ ++A+NGT+ GCP K++ C S C+ Sbjct: 1525 LGGVPDLPESFPVRMRQFVGCMRNLQVDSRHIDMADFIANNGTVPGCPAKKNVCDSNTCH 1584 Query: 1324 NGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLRPIQLPWLNALSI 1383 NG C + WD + C+C G GK CA P F G +++++ L PI PW +L Sbjct: 1585 NGGTCVNQWDAFSCECPLGFGGKSCAQEMANPQHFLGSSLVAWHGLSLPISQPWYLSLMF 1644 Query: 1384 RTRQRDAFVM----------SIQLKSGLLHYSYNG-----ETMYLPMATLSDGAWHRIEI 1428 RTRQ D ++ ++QL+ G + S G ++ L +DG WH ++ Sbjct: 1645 RTRQADGVLLQAITRGRSTITLQLREGHVMLSVEGTGLQASSLRLEPGRANDGDWHHAQL 1704 Query: 1429 KWLGTD-----ISVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGLLASDVGFFE 1483 LG ++ DYG + L ++ G ++ I +GG+ AG +A F Sbjct: 1705 A-LGASGGPGHAILSFDYGQQRA-EGNLGPRLHGLHLSNITVGGIPGPAGGVARG---FR 1759 Query: 1484 GCIQDVRIGTAQSLLNR--PTVRE--NVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTC 1539 GC+Q VR+ +N P+ E NV GC C + CP S C WDS +C+C Sbjct: 1760 GCLQGVRVSDTPEGVNSLDPSHGESINVEQGCSLPDPCDSNPCPANSYCSNDWDSYSCSC 1819 Query: 1540 EAGRVGPQCVSACELGPCG-AARCV-PDQTPKGYSCACEPGYTLTTSGCIESGKEECPGG 1597 + G G C + C+L PC + C P GY+C C P Y C + CP G Sbjct: 1820 DPGYYGDNCTNVCDLNPCEHQSVCTRKPSAPHGYTCECPPNYL--GPYCETRIDQPCPRG 1877 Query: 1598 WWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCE 1657 WWG CGPC CDV++G+ P CNK +G+CHCKENHY+P G+ CL C CY GS + C+ Sbjct: 1878 WWGHPTCGPCNCDVSKGFDPDCNKTSGECHCKENHYRPPGSPTCLLCDCYPTGSLSRVCD 1937 Query: 1658 AATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETI 1717 GQC C+PGVIGR CD C N +AEVT N GCEV YD CPR+ G+WWPRT+FG+ Sbjct: 1938 PEDGQCPCKPGVIGRQCDRCDNPFAEVTTN-GCEVNYDSCPRAIEAGIWWPRTRFGLPAA 1996 Query: 1718 TDCPPGSSGRATRTCDETKDVPWQDPDMFNCTTATFYQLRKQLHKIETGELTMNTFVGVR 1777 CP GS G A R CDE + W P++FNCT+ TF +L+ +++ E +++ + Sbjct: 1997 APCPKGSFGTAVRHCDEHRG--WLPPNLFNCTSITFSELKGFAERLQRNESGLDSGRSQQ 2054 Query: 1778 VAADLSTACANTPRLYGADVVVAEGILLELMDYELRQAGLNLTHSQDKDYVRNLLKSTNT 1837 +A L A +T +G+DV VA + L+ +E Q G L+ +QD + NLL+ + Sbjct: 2055 LALLLRNATQHTAGYFGSDVKVAYQLATRLLAHESTQRGFGLSATQDVHFTENLLRVGSA 2114 Query: 1838 ILNVEYEREWKRIRELTGHGAELLVQKFDEYIAVLAESQHDTYTSPFEIVTKDVVISVDT 1897 +L+ +R W+ I++ G G L+Q ++ Y + LA++ TY SPF IVT ++VISV Sbjct: 2115 LLDTANKRHWELIQQTEG-GTAWLLQHYEAYASALAQNMRHTYLSPFTIVTPNIVISVVR 2173 Query: 1898 VTSESIYGFEPTQLNRLNVDS-YTTERVVALPDTSAFIHSP 1937 + + G + + L + E V LP+ S F +P Sbjct: 2174 LDKGNFAGAKLPRYEALRGEQPPDLETTVILPE-SVFRETP 2213 Score = 363 bits (892), Expect = 5e-98 Identities = 253/759 (33%), Positives = 374/759 (49%), Gaps = 44/759 (5%) Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY---AIIGGNTQMQFSIDS 204 PQF +Y +V E+ PV A ++A D D G + Y A+ + FS+D Sbjct: 179 PQFQPPSYQATVPEN-QPAGTPV-ASLRAIDPDEGEAGRLEYTMDALFDSRSNQFFSLDP 236 Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 ++G V+ + LD E ++ + AQD G P RS L I + D ND+ P F ++E Sbjct: 237 VTGAVTTAEELDRETKSTHVFRVTAQDHGMPRRSALATLTILVTDTNDHDPVFEQQEYKE 296 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 S+ EN+ +GY ++ V+A D D NA + Y + + G+ IDPRSG + T G + Sbjct: 297 SLRENLEVGYEVLTVRATDGDAPPNANILYRLLEGS-GGSPSEVFEIDPRSGVIRTRGPV 355 Query: 325 DRETQAKYQLLVTATD-GGDP-PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382 DRE YQL V A+D G DP PRS TA F +Y V++ ED PG Sbjct: 356 DREEVESYQLTVEASDQGRDPGPRSTTAAVFLSVEDDNDNAPQFSEKRYVVQVREDVTPG 415 Query: 383 TPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440 PV+ +TA+D D+ + +HY I GN RG+F + +Q G + V PLD++ + Y L Sbjct: 416 APVLRVTASDRDKGSNAVVHYSIMSGNARGQFYLDAQT--GALDVVSPLDYETTKEYTLR 473 Query: 441 VSATDSGGR----SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496 V A D GGR + + +V + + D N+ AP+F + P+ A+V E P+G VL V A D+ Sbjct: 474 VRAQD-GGRPPLSNVSGLVTVQVLDINDNAPIFVSTPFQATVLESVPLGYLVLHVQAIDA 532 Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556 D G NA++ Y L A HD F IN TG I+ LDRE + Y V ARD Sbjct: 533 DAGDNARLEYRL-------AGVGHDFPFTINNGTGWISVAAELDREEVDFYSFGVEARDH 585 Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616 G P+L+ + V ++V+DVNDN P F Q YT + EDA VGTSV V A D D + I Sbjct: 586 GTPALTASASVSVTVLDVNDNNPTFTQPEYTVRLNEDAAVGTSVVTVSAVDRDA--HSVI 643 Query: 617 HYEL-DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675 Y++ R S G++ LD + + L A DG + T + + Sbjct: 644 TYQITSGNTRNRFSITSQSGGGLVSLALPLDYKLERQYVLAVTASDG---TRQDTAQIVV 700 Query: 676 KIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735 + D N PVF+S T ++E+ P GTT+ I A D D G NA + Y ++ D F Sbjct: 701 NVTDANTHRPVFQSSHYTVNVNEDRPAGTTVVLISATDEDTGENARITYFME--DSIPQF 758 Query: 736 SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAP 792 ++ +D + T +LDYE + Y L I A P + +EILV DVNDNAP Sbjct: 759 RID----ADTGAVTTQAELDYED-QVSYTLAITARDNGIPQKSDTTYLEILVNDVNDNAP 813 Query: 793 VMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSM- 849 + Y+D P ++ A D D + ++ Y G++ + + E+T + Sbjct: 814 QFLRDSYQGSVYEDVPPFTSVLQISATDRDSGLNGRVFYTFQGGDDGDGDFIVESTSGIV 873 Query: 850 -TLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887 TL NV + +V G+ + M+++V ++ Sbjct: 874 RTLRRLDRENVAQYVLRAYAVDKGMPPARTPMEVTVTVL 912 Score = 361 bits (888), Expect = 2e-97 Identities = 273/851 (32%), Positives = 414/851 (48%), Gaps = 69/851 (8%) Query: 20 SPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXX 79 +P F+ Y+A+V E +GT V +L+A D D G+ +EYT++ + N Sbjct: 178 APQFQPPSYQATVPENQPAGTPVASLRAIDPDEGEAGRLEYTMDALFDSRSN-------- 229 Query: 80 XXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVN 139 F +D +GA+ T LDRE + + V A D P R S+ AT+ + Sbjct: 230 --------QFFSLDPVTGAVTTAEELDRETKSTHVFRVTAQDHGMP---RRSALATLTIL 278 Query: 140 IIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII---GGNT 196 + D ND+ P F ++ Y S+ E++ V + ++ATD D N+ I Y ++ GG+ Sbjct: 279 VTDTNDHDPVFEQQEYKESLRENLEV--GYEVLTVRATDGDAPPNANILYRLLEGSGGSP 336 Query: 197 QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD-GGSPS-RSNTTQLLINIRDVNDNA 254 F ID SG + +D E+V SY+L + A D G P RS T + +++ D NDNA Sbjct: 337 SEVFEIDPRSGVIRTRGPVDREEVESYQLTVEASDQGRDPGPRSTTAAVFLSVEDDNDNA 396 Query: 255 PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR 314 P+F + V E+V G ++RV A D D+G NA + Y++ +GN +D + Sbjct: 397 PQFSEKRYVVQVREDVTPGAPVLRVTASDRDKGSNAVVHYSI----MSGNARGQFYLDAQ 452 Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRS-ATATXXXXXXXXXXXXXXFMPGQYEV 373 +G + LD ET +Y L V A DGG PP S + F+ ++ Sbjct: 453 TGALDVVSPLDYETTKEYTLRVRAQDGGRPPLSNVSGLVTVQVLDINDNAPIFVSTPFQA 512 Query: 374 ELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431 + E P G V+ + A DAD DN RL Y + G F T NG G I+VA LD Sbjct: 513 TVLESVPLGYLVLHVQAIDADAGDNARLEYRLAG--VGHDFPFTINNGTGWISVAAELDR 570 Query: 432 KQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVL 489 ++ Y V A D G + TA +++T D N+ P F YT + EDA +GT+V+ Sbjct: 571 EEVDFYSFGVEARDHGTPALTASASVSVTVLDVNDNNPTFTQPEYTVRLNEDAAVGTSVV 630 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA--ITTNKLLDRETMSGY 547 VSA D D ++ ITY ++S + +F I Q+G ++ LD + Y Sbjct: 631 TVSAVDRDA--HSVITYQITS-------GNTRNRFSITSQSGGGLVSLALPLDYKLERQY 681 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 +L VTA DG + DT + ++V D N + PVF+ YT N+ ED GT+V + ATD Sbjct: 682 VLAVTASDG---TRQDTAQIVVNVTDANTHRPVFQSSHYTVNVNEDRPAGTTVVLISATD 738 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 D G N RI Y ++ + F ID +G + T LD E ++ L A D G P + Sbjct: 739 EDTGENARITYFMEDSIPQ---FRIDADTGAVTTQAELDYEDQVSYTLAITARDNGIPQK 795 Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 S T + I + D+ND+ P F D + E+ P T++ +I A D D G N V Y+ + Sbjct: 796 SDTTYLEILVNDVNDNAPQFLRDSYQGSVYEDVPPFTSVLQISATDRDSGLNGRVFYTFQ 855 Query: 728 GGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKKYEL---VIRAASPPLWNDVRVEIL 783 GGDD + F +E+ G + T+ LD E+ +Y L + PP + V + Sbjct: 856 GGDDGDGDFIVESTSGIVR----TLRRLDRENV-AQYVLRAYAVDKGMPPARTPMEVTVT 910 Query: 784 VTDVNDNAPVMKDFQI-IFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILSGNNANL 839 V DVNDN PV + + +F ++ P+G RV A D D ++ Y+I+ GN + Sbjct: 911 VLDVNDNPPVFEQDEFDVF--VEENSPIGLAVARVTATDPDEGTNAQIMYQIVEGNIPEV 968 Query: 840 ILLNETTGSMT 850 L+ +G +T Sbjct: 969 FQLDIFSGELT 979 Score = 281 bits (688), Expect = 3e-73 Identities = 203/635 (31%), Positives = 311/635 (48%), Gaps = 29/635 (4%) Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 R+VN AP+F +Q +V EN P G + ++A D DEG L YTM D + + Sbjct: 173 RNVN-TAPQFQPPSYQATVPENQPAGTPVASLRAIDPDEGEAGRLEYTM-DALFDSRSNQ 230 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 ++DP +G V T+ +LDRET++ + VTA D G P RSA AT F Sbjct: 231 FFSLDPVTGAVTTAEELDRETKSTHVFRVTAQDHGMPRRSALATLTILVTDTNDHDPVFE 290 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLH--YEITGGNTRGRFSITSQNGRGL 422 +Y+ L E+ G V+T+ ATD D N L+ E +GG+ F I ++ G+ Sbjct: 291 QQEYKESLRENLEVGYEVLTVRATDGDAPPNANILYRLLEGSGGSPSEVFEIDPRS--GV 348 Query: 423 ITVAQPLDFKQERRYVLTVSATDS----GGRSDTAMVQINITDANNYAPVFENAPYTASV 478 I P+D ++ Y LTV A+D G RS TA V +++ D N+ AP F Y V Sbjct: 349 IRTRGPVDREEVESYQLTVEASDQGRDPGPRSTTAAVFLSVEDDNDNAPQFSEKRYVVQV 408 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 ED G VL V+A+D D G NA + YS+ S + QF ++ QTGA+ Sbjct: 409 REDVTPGAPVLRVTASDRDKGSNAVVHYSIMS-------GNARGQFYLDAQTGALDVVSP 461 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTD-VEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LD ET Y L V A+DGG P LS+ + V + V+D+NDN P+F + A ++E +G Sbjct: 462 LDYETTKEYTLRVRAQDGGRPPLSNVSGLVTVQVLDINDNAPIFVSTPFQATVLESVPLG 521 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 V V A DAD G N R+ Y L + F I+ +G I LDRE V + Sbjct: 522 YLVLHVQAIDADAGDNARLEYRLAGVG-HDFPFTINNGTGWISVAAELDREEVDFYSFGV 580 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A D GTP +++ V + + D+ND+ P F T ++E++ +GT++ + A D D Sbjct: 581 EARDHGTPALTASASVSVTVLDVNDNNPTFTQPEYTVRLNEDAAVGTSVVTVSAVDRD-- 638 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND 777 ++V+ Y I G+ N FS+ ++ G L + LDY+ R +Y L + A+ + Sbjct: 639 AHSVITYQITSGNTRNRFSITSQSGGGLVSLA--LPLDYKLER-QYVLAVTASDGTRQDT 695 Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNN 836 ++ + VTD N + PV + N +D P G + A D D + + ++ Sbjct: 696 AQIVVNVTDANTHRPVFQSSHYTVNVNED-RPAGTTVVLISATDEDTGENARITYFMEDS 754 Query: 837 ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 ++ TG++T +L+ T+ ++ D Sbjct: 755 IPQFRIDADTGAVTTQAELDYEDQVSYTLAITARD 789 Score = 214 bits (523), Expect = 3e-53 Identities = 155/438 (35%), Positives = 223/438 (50%), Gaps = 26/438 (5%) Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523 N AP F+ Y A+V E+ P GT V + A D D G ++ Y++ + + + +Q Sbjct: 176 NTAPQFQPPSYQATVPENQPAGTPVASLRAIDPDEGEAGRLEYTMDALFDSRS----NQF 231 Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583 F ++P TGA+TT + LDRET S ++ VTA+D G+P S + I V D ND++PVF+Q Sbjct: 232 FSLDPVTGAVTTAEELDRETKSTHVFRVTAQDHGMPRRSALATLTILVTDTNDHDPVFEQ 291 Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS--FVIDPASGVIRT 641 Q Y ++ E+ VG V V ATD D N I Y L S F IDP SGVIRT Sbjct: 292 QEYKESLRENLEVGYEVLTVRATDGDAPPNANILYRLLEGSGGSPSEVFEIDPRSGVIRT 351 Query: 642 NKALDRESVATHDLKAVAIDGGTP--PQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699 +DRE V ++ L A D G P+S+T V + +ED ND+ P F + E+ Sbjct: 352 RGPVDREEVESYQLTVEASDQGRDPGPRSTTAAVFLSVEDDNDNAPQFSEKRYVVQVRED 411 Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759 G + + A D D+G NAVVHYSI G+ F L+ + G+ L + LDYE+ Sbjct: 412 VTPGAPVLRVTASDRDKGSNAVVHYSIMSGNARGQFYLDAQTGA----LDVVSPLDYET- 466 Query: 760 RKKYELVIRA---ASPPLWN-DVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFPVGPF 813 K+Y L +RA PPL N V + V D+NDNAP V FQ + P+G Sbjct: 467 TKEYTLRVRAQDGGRPPLSNVSGLVTVQVLDINDNAPIFVSTPFQA---TVLESVPLGYL 523 Query: 814 G-RVPAYDADVTD--KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVT 870 V A DAD D +L+YR+ + +N TG ++++ +L+ + V Sbjct: 524 VLHVQAIDADAGDNARLEYRLAGVGHDFPFTINNGTGWISVAAELDREEVDFYSFGVEAR 583 Query: 871 D-GVNEIKAMMQLSVRLI 887 D G + A +SV ++ Sbjct: 584 DHGTPALTASASVSVTVL 601 Score = 125 bits (301), Expect = 2e-26 Identities = 104/337 (30%), Positives = 159/337 (47%), Gaps = 38/337 (11%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I V D ND++P F Y+ SV E T+VL + ATD+D G N V YT + Sbjct: 802 EILVNDVNDNAPQFLRDSYQGSVYEDVPPFTSVLQISATDRDSGLNGRVFYTFQ------ 855 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 +D F ++ SG + T LDRE VA+Y + A D+ P + Sbjct: 856 -GGDDGDGD-----------FIVESTSGIVRTLRRLDRENVAQYVLRAYAVDKGMPPA-- 901 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + + V ++D NDN P F + + V V+E+ + +A++ ATD D G N+ I Y Sbjct: 902 -RTPMEVTVTVLDVNDNPPVFEQDEFDVFVEENSPI--GLAVARVTATDPDEGTNAQIMY 958 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I+ GN F +D SG+++ + LDYE Y LVI+A SR+ + + + D Sbjct: 959 QIVEGNIPEVFQLDIFSGELTALVDLDYEDRPEYVLVIQATSAPLVSRAT---VHVRLLD 1015 Query: 250 VNDNAPRF--YTSLFQESV---SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 NDN P + LF V S + P G +I RV A+D D ++ LTY+ GN Sbjct: 1016 RNDNPPVLGNFEILFNNYVTNRSSSFP-GGAIGRVPAHDPD--ISDSLTYSFE----RGN 1068 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341 + ++ +G + S LD + + V +DG Sbjct: 1069 ELSLVLLNASTGELKLSRALDNNRPLEAIMSVLVSDG 1105 Score = 54.8 bits (126), Expect = 3e-05 Identities = 45/148 (30%), Positives = 79/148 (53%), Gaps = 18/148 (12%) Query: 2176 LKKPIRLQIWLDINRETFGSRTNPQCVHWS---TLRGSGEWSRVGCHTEIDYDWSPYSEE 2232 L KP+ +Q L E RT P CV W+ + G+G WS GC E+ + + Sbjct: 2298 LDKPVTVQFRLLETEE----RTKPICVFWNHSILVSGTGGWSARGC--EVVFRNESH--- 2348 Query: 2233 PLLINCTCNHLSTFAVLVDEVDVEFIPEPSLLESVTSYTAFSISLPLLLTSWAALCLIRG 2292 ++C CNH+++FAVL+D V E L+++T Y A ++L LL ++ L L+R Sbjct: 2349 ---VSCQCNHMTSFAVLMD-VSRRENGEILPLKTLT-YVALGVTLAALLLTFFFLTLLR- 2402 Query: 2293 GAATVSNSIHKHLIFSVFMAELLYLIAL 2320 + + I ++L ++ +A+L++L+ + Sbjct: 2403 ILRSNQHGIRRNLTAALGLAQLVFLLGI 2430 Score = 37.5 bits (83), Expect = 5.3 Identities = 23/76 (30%), Positives = 30/76 (39%), Gaps = 6/76 (7%) Query: 1509 DGCQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC-VSA----CELGPCGAARC 1562 D C++ D C C P+ +C + TC C G G C VSA C G C Sbjct: 1283 DYCETEVDLCYSRPCGPHGRCRSREGGYTCLCRDGYTGEHCEVSARSGRCTPGVCKNGGT 1342 Query: 1563 VPDQTPKGYSCACEPG 1578 + G+ C C G Sbjct: 1343 CVNLLVGGFKCDCPSG 1358 >UniRef50_Q4RXP0 Cluster: Chromosome 11 SCAF14979, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 11 SCAF14979, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 2982 Score = 810 bits (2004), Expect = 0.0 Identities = 434/943 (46%), Positives = 593/943 (62%), Gaps = 45/943 (4%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D NDH+PVFE Q Y+ ++RE G VLT++ATD D N + Y I + Sbjct: 257 ITVSDTNDHNPVFEQQDYKENIRENLEIGYEVLTVRATDGDAPVNGNILYRI-------I 309 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N + DVF ID RSG + TR +DRE+V Y +LV+A DQ R Sbjct: 310 NGNGS-----------NDVFEIDSRSGVIRTRGLVDREQVEAYMLLVEANDQGRDPGPR- 357 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+TAT+H+ + DDNDN PQFSEK Y V V ED++ N I ++ ATD D G+N+ + ++ Sbjct: 358 SATATVHIVVEDDNDNAPQFSEKRYVVQVPEDMA--PNTEILQVTATDEDRGSNAVVHFS 415 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIRD 249 I+ GNT+ QF ID+ +G + LV LDYE + Y L IRAQDGG P SN + L+ + + D Sbjct: 416 IMSGNTRGQFYIDAQTGKMDLVSHLDYEANKEYTLRIRAQDGGRPPLSNISGLVTVQVLD 475 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 VNDNAP F ++ FQ +V ENVP+GYSI+ +QA DAD G N+ L Y +T T N P Sbjct: 476 VNDNAPIFVSTPFQATVLENVPLGYSIIHIQAVDADSGDNSRLEYRLTST--TPN--FPF 531 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 I+ +GW+ + +LDRE+ Y V A D G P S++A+ F Sbjct: 532 AINNSTGWIVVAAELDRESVDFYNFGVEARDQGYPVMSSSASISMTVLDVNDNNPEFTQK 591 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 Y + L ED GT V+T++A D D ++ + Y+I+ GNTR RFSITSQ+G GLIT+A PL Sbjct: 592 AYYMRLNEDAAVGTSVLTVSAVDQDINSVVTYQISSGNTRNRFSITSQSGGGLITLALPL 651 Query: 430 DFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 D+K ER+YVLT++A+D G DTA V +N+TDAN + PVF+++ YT ++ ED P+GTTV+ Sbjct: 652 DYKLERQYVLTITASD-GTLFDTAKVFVNVTDANTHRPVFQSSHYTVNINEDRPMGTTVV 710 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 ++SATD D G NA+ITY + I QF I+P +GA+TT LD E Y L Sbjct: 711 LISATDEDTGENARITYFMDDSIP---------QFDIDPDSGAVTTQMELDYEDQVSYTL 761 Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 +TARD G+P SDTT +EI V DVNDN P F + Y ++MED V TSV QV ATD D Sbjct: 762 AITARDNGIPQKSDTTYLEILVNDVNDNGPRFLRDHYVGSVMEDVPVFTSVVQVSATDRD 821 Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669 GLNGR+ Y + +G F+I+ SG++RT + LDRE+V ++L+A A+D G P + Sbjct: 822 SGLNGRVFYTFQGGEDGDGDFIIESTSGIVRTLRRLDRENVPVYNLQAFAVDKGVPALKT 881 Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729 V +H+ I D+ND+PPVFE D L + ENSPIG +G + A DPDEG NA + Y I G Sbjct: 882 PVNIHVTILDVNDNPPVFEKDELDIMVEENSPIGLVVGHVSATDPDEGSNAQIMYQIVEG 941 Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVND 789 + F L+ G EL +++DLDYE+ R +Y +V++A S PL + V I + D ND Sbjct: 942 NIPEVFQLDIFSG----ELTSLIDLDYET-RNEYVIVVQATSAPLVSRATVHIKLVDKND 996 Query: 790 NAPVMKDFQIIFNNY----KDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNET 845 N PV+K+FQIIFNNY FP G GR+PA+D DV+D+L Y GN NL+LLN++ Sbjct: 997 NVPVLKNFQIIFNNYVTNKYSSFPSGVIGRIPAHDPDVSDQLHYSFEVGNELNLVLLNQS 1056 Query: 846 TGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTA 905 TG + LS L+ N P A+M +SV+DGV+ + A L V +IT+EML NSIT+RL + + Sbjct: 1057 TGEIQLSQALDNNRPLEASMRISVSDGVHAVSAQCLLQVTIITDEMLSNSITLRLANTSQ 1116 Query: 906 EQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILN 948 EQFLS LL F+DG+A ++ ++++ IF++QDDTDV+ ILN Sbjct: 1117 EQFLSLLLAQFLDGVARVLSASRQDVVIFNIQDDTDVSARILN 1159 Score = 395 bits (973), Expect = e-108 Identities = 200/503 (39%), Positives = 273/503 (54%), Gaps = 39/503 (7%) Query: 1256 LDLTGPLQIGGLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRS 1315 LDLTGPL +GG+P +P F V+N+ F+GCI + +D++ +D+ S++A+NGTL GC KR Sbjct: 1524 LDLTGPLLLGGVPKLPEDFPVRNRQFMGCIRNLRVDNQHVDMASFIANNGTLPGCSAKRH 1583 Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLRPIQ- 1374 C++ PC NG C +LW ++ CDC G GK C P RF G+ +L +N + Sbjct: 1584 FCNTNPCLNGGTCVNLWGSFSCDCPLGFGGKSCERVMASPQRFLGNSLLQWNNMAAVASS 1643 Query: 1375 LPWLNALSIRTRQRDAFVMSI----------QLKSGL----LHYSYNGETMYLPMATLSD 1420 +PW L +RTRQ A ++ I QL+ G LH N L ++D Sbjct: 1644 VPWHVELMLRTRQASAILLHISSGLQHNLTLQLRDGSVLMGLHQGENSTLSRLEEVLVND 1703 Query: 1421 GAWH--RIEIKWLGTDIS-----VTVDYGL--RTVLMPMLAN-----KIQGQYIGKILIG 1466 G WH +++I LG +S +++D GL R P A+ K++ + + +G Sbjct: 1704 GEWHHLQLDISSLGRPLSHHKAVLSLDQGLYLREAAAPFQASMEVDGKLRESKLKTVSVG 1763 Query: 1467 GLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRPTVRENVRDGCQSRADCMLSICPPYS 1526 GL G + F GCIQ +RIG A SL V NV GC C + CP S Sbjct: 1764 GLAAPGGKILQG---FRGCIQGLRIGGALSLSQARKV--NVEPGCSVPDPCSSNPCPANS 1818 Query: 1527 KCVTSWDSSTCTCEAGRVGPQCVSACELGPCG-AARCVPD-QTPKGYSCACEPGYTLTTS 1584 C WDS +CTC G G C AC L PC + C + +GY+C C Y Sbjct: 1819 YCRDDWDSHSCTCLTGFYGNNCTDACSLNPCEHESVCTRRLSSSRGYTCDCSRNYF--GH 1876 Query: 1585 GCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPC 1644 C + CP G WG CGPC C +G+ CNK +G+C CK+NHY+PEG+ CL C Sbjct: 1877 YCEKKTDLPCPRGQWGHKTCGPCNCQTDKGFDFDCNKTSGECRCKDNHYRPEGSGGCLLC 1936 Query: 1645 QCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTPNSGCEVVYDGCPRSFAGG 1704 CY GS + +C+ +GQC C+PGVIGR CD C N +AEV+ N GCEV+YD CP++ G Sbjct: 1937 DCYPLGSFSRACDRDSGQCQCKPGVIGRQCDRCDNPFAEVSAN-GCEVIYDSCPQAIEAG 1995 Query: 1705 VWWPRTKFGVETITDCPPGSSGR 1727 +WWPRTKFG+ CP G+ GR Sbjct: 1996 IWWPRTKFGLPAAVSCPRGTLGR 2018 Score = 353 bits (869), Expect = 3e-95 Identities = 263/832 (31%), Positives = 395/832 (47%), Gaps = 59/832 (7%) Query: 33 REGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRI 92 R + G L LKA D D G+ +EY IE + N +F + Sbjct: 171 RRTSQPGRPSLVLKAVDADEGEAGRLEYFIEALFDSRSN----------------SLFAV 214 Query: 93 DGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSE 152 D +GA+ T LDRE + V A D +P R ++ AT+ + + D ND+ P F + Sbjct: 215 DPANGAVSTVEVLDRETKDTHVFRVTAVDHGAP---RRTAMATLTITVSDTNDHNPVFEQ 271 Query: 153 KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN-TQMQFSIDSLSGDVSL 211 + Y ++ E++ + + ++ATD D N I Y II GN + F IDS SG + Sbjct: 272 QDYKENIRENLEI--GYEVLTVRATDGDAPVNGNILYRIINGNGSNDVFEIDSRSGVIRT 329 Query: 212 VKTLDYEQVRSYRLVIRAQD-GGSPS-RSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269 +D EQV +Y L++ A D G P RS T + I + D NDNAP+F + V E+ Sbjct: 330 RGLVDREQVEAYMLLVEANDQGRDPGPRSATATVHIVVEDDNDNAPQFSEKRYVVQVPED 389 Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329 + I++V A D D G NA + +++ +GN ID ++G + LD E Sbjct: 390 MAPNTEILQVTATDEDRGSNAVVHFSI----MSGNTRGQFYIDAQTGKMDLVSHLDYEAN 445 Query: 330 AKYQLLVTATDGGDPPRS-ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388 +Y L + A DGG PP S + F+ ++ + E+ P G ++ + Sbjct: 446 KEYTLRIRAQDGGRPPLSNISGLVTVQVLDVNDNAPIFVSTPFQATVLENVPLGYSIIHI 505 Query: 389 TATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446 A DAD +++RL Y +T +T F N G I VA LD + Y V A D Sbjct: 506 QAVDADSGDNSRLEYRLT--STTPNFPFAINNSTGWIVVAAELDRESVDFYNFGVEARDQ 563 Query: 447 G--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504 G S +A + + + D N+ P F Y + EDA +GT+VL VSA D D IN+ + Sbjct: 564 GYPVMSSSASISMTVLDVNDNNPEFTQKAYYMRLNEDAAVGTSVLTVSAVDQD--INSVV 621 Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTGA--ITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 TY +SS + +F I Q+G IT LD + Y+LT+TA DG +L Sbjct: 622 TYQISS-------GNTRNRFSITSQSGGGLITLALPLDYKLERQYVLTITASDG---TLF 671 Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP 622 DT V ++V D N + PVF+ YT NI ED +GT+V + ATD D G N RI Y +D Sbjct: 672 DTAKVFVNVTDANTHRPVFQSSHYTVNINEDRPMGTTVVLISATDEDTGENARITYFMDD 731 Query: 623 KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND 682 + F IDP SG + T LD E ++ L A D G P +S T + I + D+ND Sbjct: 732 SIPQ---FDIDPDSGAVTTQMELDYEDQVSYTLAITARDNGIPQKSDTTYLEILVNDVND 788 Query: 683 SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN-SFSLETRQ 741 + P F D + E+ P+ T++ ++ A D D G N V Y+ +GG+D + F +E+ Sbjct: 789 NGPRFLRDHYVGSVMEDVPVFTSVVQVSATDRDSGLNGRVFYTFQGGEDGDGDFIIESTS 848 Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801 G + +D + + P L V + + + DVNDN PV + ++ Sbjct: 849 GI--VRTLRRLDRENVPVYNLQAFAVDKGVPALKTPVNIHVTILDVNDNPPVFEKDELDI 906 Query: 802 NNYKDCFPVG-PFGRVPAYDADVTDKLQ--YRILSGNNANLILLNETTGSMT 850 ++ P+G G V A D D Q Y+I+ GN + L+ +G +T Sbjct: 907 -MVEENSPIGLVVGHVSATDPDEGSNAQIMYQIVEGNIPEVFQLDIFSGELT 957 Score = 343 bits (843), Expect = 4e-92 Identities = 239/733 (32%), Positives = 361/733 (49%), Gaps = 44/733 (6%) Query: 174 IKATDADVGANSAIRY---AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ 230 +KA DAD G + Y A+ + F++D +G VS V+ LD E ++ + A Sbjct: 183 LKAVDADEGEAGRLEYFIEALFDSRSNSLFAVDPANGAVSTVEVLDRETKDTHVFRVTAV 242 Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290 D G+P R+ L I + D ND+ P F ++E++ EN+ IGY ++ V+A D D VN Sbjct: 243 DHGAPRRTAMATLTITVSDTNDHNPVFEQQDYKENIRENLEIGYEVLTVRATDGDAPVNG 302 Query: 291 ELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD-GGDP-PRSA 348 + Y + + + + +V ID RSG + T G +DRE Y LLV A D G DP PRSA Sbjct: 303 NILYRIINGNGSNDV---FEIDSRSGVIRTRGLVDREQVEAYMLLVEANDQGRDPGPRSA 359 Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGG 406 TAT F +Y V++ ED P T ++ +TATD D + +H+ I G Sbjct: 360 TATVHIVVEDDNDNAPQFSEKRYVVQVPEDMAPNTEILQVTATDEDRGSNAVVHFSIMSG 419 Query: 407 NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR----SDTAMVQINITDA 462 NTRG+F I +Q G+ + + LD++ + Y L + A D GGR + + +V + + D Sbjct: 420 NTRGQFYIDAQTGK--MDLVSHLDYEANKEYTLRIRAQD-GGRPPLSNISGLVTVQVLDV 476 Query: 463 NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522 N+ AP+F + P+ A+V E+ P+G +++ + A D+D G N+++ Y L+S N Sbjct: 477 NDNAPIFVSTPFQATVLENVPLGYSIIHIQAVDADSGDNSRLEYRLTSTTPN-------F 529 Query: 523 QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582 F IN TG I LDRE++ Y V ARD G P +S + + ++V+DVNDN P F Sbjct: 530 PFAINNSTGWIVVAAELDRESVDFYNFGVEARDQGYPVMSSSASISMTVLDVNDNNPEFT 589 Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP-KDREEGSFVIDPASGVIRT 641 Q+ Y + EDA VGTSV V A D D+ N + Y++ R S G+I Sbjct: 590 QKAYYMRLNEDAAVGTSVLTVSAVDQDI--NSVVTYQISSGNTRNRFSITSQSGGGLITL 647 Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701 LD + + L A DG T V + + D N PVF+S T I+E+ P Sbjct: 648 ALPLDYKLERQYVLTITASDG---TLFDTAKVFVNVTDANTHRPVFQSSHYTVNINEDRP 704 Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761 +GTT+ I A D D G NA + Y + D F ++ D + T ++LDYE + Sbjct: 705 MGTTVVLISATDEDTGENARITYFM--DDSIPQFDID----PDSGAVTTQMELDYED-QV 757 Query: 762 KYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA 818 Y L I A P + +EILV DVNDN P + + +D +V A Sbjct: 758 SYTLAITARDNGIPQKSDTTYLEILVNDVNDNGPRFLRDHYVGSVMEDVPVFTSVVQVSA 817 Query: 819 YDAD--VTDKLQYRILSGNNANLILLNETTGSM--TLSPQLNTNVPKLATMEVSVTDGVN 874 D D + ++ Y G + + + E+T + TL NVP +V GV Sbjct: 818 TDRDSGLNGRVFYTFQGGEDGDGDFIIESTSGIVRTLRRLDRENVPVYNLQAFAVDKGVP 877 Query: 875 EIKAMMQLSVRLI 887 +K + + V ++ Sbjct: 878 ALKTPVNIHVTIL 890 Score = 215 bits (526), Expect = 1e-53 Identities = 156/505 (30%), Positives = 235/505 (46%), Gaps = 25/505 (4%) Query: 381 PGTPVVTLTATDADED--NRLHYEITG-GNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437 PG P + L A DADE RL Y I ++R G ++ + LD + + + Sbjct: 176 PGRPSLVLKAVDADEGEAGRLEYFIEALFDSRSNSLFAVDPANGAVSTVEVLDRETKDTH 235 Query: 438 VLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495 V V+A D G TAM + IT D N++ PVFE Y ++ E+ IG VL V ATD Sbjct: 236 VFRVTAVDHGAPRRTAMATLTITVSDTNDHNPVFEQQDYKENIRENLEIGYEVLTVRATD 295 Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555 D +N I Y + + + V F I+ ++G I T L+DRE + Y+L V A D Sbjct: 296 GDAPVNGNILYRIINGNGSNDV------FEIDSRSGVIRTRGLVDREQVEAYMLLVEAND 349 Query: 556 GG--VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613 G S T V I V D NDN P F ++ Y + ED T + QV ATD D G N Sbjct: 350 QGRDPGPRSATATVHIVVEDDNDNAPQFSEKRYVVQVPEDMAPNTEILQVTATDEDRGSN 409 Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS-TVI 672 +H+ + G F ID +G + LD E+ + L+ A DGG PP S+ + + Sbjct: 410 AVVHFSI-MSGNTRGQFYIDAQTGKMDLVSHLDYEANKEYTLRIRAQDGGRPPLSNISGL 468 Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732 V +++ D+ND+ P+F S + EN P+G +I I+A D D G N+ + Y + + Sbjct: 469 VTVQVLDVNDNAPIFVSTPFQATVLENVPLGYSIIHIQAVDADSGDNSRLEYRLTSTTPN 528 Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVND 789 F++ G +V +LD ES Y + A P + + + + V DVND Sbjct: 529 FPFAINNSTG----WIVVAAELDRESV-DFYNFGVEARDQGYPVMSSSASISMTVLDVND 583 Query: 790 NAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGS- 848 N P +D V A D D+ + Y+I SGN N + +G Sbjct: 584 NNPEFTQKAYYMRLNEDAAVGTSVLTVSAVDQDINSVVTYQISSGNTRNRFSITSQSGGG 643 Query: 849 -MTLSPQLNTNVPKLATMEVSVTDG 872 +TL+ L+ + + + ++ +DG Sbjct: 644 LITLALPLDYKLERQYVLTITASDG 668 Score = 132 bits (319), Expect = 1e-28 Identities = 64/169 (37%), Positives = 96/169 (56%), Gaps = 16/169 (9%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 +TC+C E +TG +C+ C +CR+G CV GG C+ C Y Sbjct: 1220 YTCECLEDYTGEHCQLSSRSGRCAP----GVCRNGGTCVNLLVGGFKCE-CP-SGGYEKP 1273 Query: 1102 VCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVS 1161 CE+ R+FP SFLTF GL++R L L FAT+ +GLLLYNGR+NE+HDF+A+E++ Sbjct: 1274 YCEMTTRNFPPHSFLTFKGLRQRFHFTLSLTFATREPNGLLLYNGRFNEKHDFIAMEIID 1333 Query: 1162 SEAGRGGGPGLRFSFSLGGGKSEIT--VEGNVGDGSWHTVEIEYFNRTI 1208 + ++ ++S G K+ + + G V DG WH VE+ Y+N+ + Sbjct: 1334 EQ--------IQLTYSAGETKTTVAPRIPGGVSDGQWHVVEVHYYNKGV 1374 Score = 122 bits (294), Expect = 1e-25 Identities = 102/337 (30%), Positives = 156/337 (46%), Gaps = 38/337 (11%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I V D ND+ P F Y SV E T+V+ + ATD+D G N V YT + Sbjct: 780 EILVNDVNDNGPRFLRDHYVGSVMEDVPVFTSVVQVSATDRDSGLNGRVFYTFQ------ 833 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 ED F I+ SG + T LDRE V Y + A D+ P Sbjct: 834 -GGEDGDGD-----------FIIESTSGIVRTLRRLDRENVPVYNLQAFAVDKGVPA--- 878 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L + IHV I+D NDN P F + + V+E+ + V+ + ATD D G+N+ I Y Sbjct: 879 LKTPVNIHVTILDVNDNPPVFEKDELDIMVEENSPI--GLVVGHVSATDPDEGSNAQIMY 936 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I+ GN F +D SG+++ + LDYE Y +V++A SR+ + I + D Sbjct: 937 QIVEGNIPEVFQLDIFSGELTSLIDLDYETRNEYVIVVQATSAPLVSRAT---VHIKLVD 993 Query: 250 VNDNAP--RFYTSLFQESVS---ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 NDN P + + +F V+ + P G I R+ A+D D V+ +L Y+ GN Sbjct: 994 KNDNVPVLKNFQIIFNNYVTNKYSSFPSGV-IGRIPAHDPD--VSDQLHYSFE----VGN 1046 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341 + ++ +G + S LD + + ++ +DG Sbjct: 1047 ELNLVLLNQSTGEIQLSQALDNNRPLEASMRISVSDG 1083 Score = 85.8 bits (203), Expect = 2e-14 Identities = 74/241 (30%), Positives = 105/241 (43%), Gaps = 35/241 (14%) Query: 1722 PGSSGRATRTCDETKDVPWQDPDMFNCTTATFYQLRKQLHKIETGELTMNTFVGVRVAAD 1781 P S G A R CDE K W P +FNCT++TF +L+ K ++ + AA Sbjct: 2055 PPSPGTAIRHCDEHKG--WLPPSLFNCTSSTFSRLQTLAEKFSHNASLLDAGHVRQTAAM 2112 Query: 1782 LSTACANTPRLYGADVVVAEGILLELMDYELRQAGLNLTHSQDKDYVRNLLKSTNTILNV 1841 L+ A +T YG+DV V ++ L+ +E Q G NLT +QD + + + T+T + Sbjct: 2113 LANATLHTETFYGSDVKVVYRLVRSLLQHESHQQGFNLTATQDVHFT-EVTRRTHTHTHT 2171 Query: 1842 EYERE-----WKRIR-----------------------ELTGH---GAELLVQKFDEYIA 1870 R W+ IR EL H G L++ F+EY Sbjct: 2172 HTHRWGRGVCWELIRPVNTQNLVRVSSAVLSPDTRPHWELIQHSEGGTAALLRCFEEYTN 2231 Query: 1871 VLAESQHDTYTSPFEIVTKDVVISVDTVTSESIYGFEPTQLNRL-NVDSYTTERVVALPD 1929 LA++ TY SPF IVT +VISVD + G + L E V LPD Sbjct: 2232 TLAQNMRKTYLSPFTIVTPHIVISVDRLKKLGFAGARLPRFQALRGPRPADLETTVTLPD 2291 Query: 1930 T 1930 + Sbjct: 2292 S 2292 Score = 81.8 bits (193), Expect = 2e-13 Identities = 67/234 (28%), Positives = 104/234 (44%), Gaps = 31/234 (13%) Query: 1 MSVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEY 60 + P IH + +LD ND+ PVFE + + V E + G V + ATD D G NA++ Y Sbjct: 879 LKTPVNIH--VTILDVNDNPPVFEKDELDIMVEENSPIGLVVGHVSATDPDEGSNAQIMY 936 Query: 61 TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT 120 I + +VF++D SG L + LD E Y ++V+AT Sbjct: 937 QI-------------------VEGNIPEVFQLDIFSGELTSLIDLDYETRNEYVIVVQAT 977 Query: 121 DQASPVSDRLSSTATIHVNIIDDNDNYPQFS--EKTYTVSVDEDISVTDNPVIAKIKATD 178 S L S AT+H+ ++D NDN P + + V S + VI +I A D Sbjct: 978 ------SAPLVSRATVHIKLVDKNDNVPVLKNFQIIFNNYVTNKYSSFPSGVIGRIPAHD 1031 Query: 179 ADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232 DV + + Y+ GN ++ +G++ L + LD + + I DG Sbjct: 1032 PDV--SDQLHYSFEVGNELNLVLLNQSTGEIQLSQALDNNRPLEASMRISVSDG 1083 Score = 57.6 bits (133), Expect = 5e-06 Identities = 32/78 (41%), Positives = 42/78 (53%), Gaps = 10/78 (12%) Query: 1032 LFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQG 1091 +FRPI+P+ C+CP GFTG CET + + G +CRS REGG C+ Sbjct: 1172 MFRPIHPIAGLRCRCPTGFTGDYCETEIDLCYSKPCGAHGVCRS-------REGGYTCE- 1223 Query: 1092 CSIDAAYTTAVCELRARS 1109 C D YT C+L +RS Sbjct: 1224 CLED--YTGEHCQLSSRS 1239 Score = 48.0 bits (109), Expect = 0.004 Identities = 43/147 (29%), Positives = 71/147 (48%), Gaps = 17/147 (11%) Query: 2176 LKKPIRLQIWLDINRETFGSRTNPQCVHWS--TLRGSGEWSRVGCHTEIDYDWSPYSEEP 2233 L KPI +Q L E R+ P CV W+ L G G WS GC E+ + S + Sbjct: 2386 LDKPISVQFRLVATEE----RSKPICVLWNHTILGGRGGWSAKGC--EVVFRNSSH---- 2435 Query: 2234 LLINCTCNHLSTFAVLVDEVDVEFIPEPSLLESVTSYTAFSISLPLLLTSWAALCLIRGG 2293 I+C C H+++FAVL+D E L V +++ ++L LL + L +R Sbjct: 2436 --ISCQCYHMTSFAVLMDVSRRE--NGEILPIKVLTWSTVGVTLGFLLLTTVFLLCLRAM 2491 Query: 2294 AATVSNSIHKHLIFSVFMAELLYLIAL 2320 SI + ++F++EL++++ + Sbjct: 2492 KCN-KTSIINNGATALFLSELIFILGI 2517 >UniRef50_A7RKF4 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 2493 Score = 617 bits (1525), Expect = e-174 Identities = 370/1118 (33%), Positives = 580/1118 (51%), Gaps = 73/1118 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 INVLD ND+ P+FE Y A + E S G VL ++A+D D G N EV+Y I L Sbjct: 116 INVLDVNDNGPIFERNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCI-------L 168 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N + F I SGA+ LDREKV YT+ V+A DQ +P Sbjct: 169 NSDGD-----------NSAFSIGEVSGAVTVMKKLDREKVPTYTLQVQAQDQGNPPR--- 214 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+T T+ + ++D ND PQFS+K Y+ ++ ED+ V N ++ ++ATD D G+N + + Sbjct: 215 SATVTVKITLLDVNDCTPQFSKKVYSATIREDVPV--NQLVTTVRATDCDQGSNGEVFFE 272 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I+ GN FSI+ ++G+V + + LDYE + + L++ AQD G P N T + I + DV Sbjct: 273 IVSGNDMNFFSINRINGEVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDV 332 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDNAP+F +S FQ + EN +G RVQAYD D G N E+T++ D LP + Sbjct: 333 NDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKDHGTNGEITFSFMQND------LPFS 386 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I+ +G + +LDRE K+ + A D G P + TA F + Sbjct: 387 INENTGGISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEE 446 Query: 371 YEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGR-FSITSQNGRGLITVAQP 428 Y +AE+ GT V+ + A D D + Y I + R F I N +GLIT++ Sbjct: 447 YHTSIAENSRWGTSVLQVKAIDPDSGPTNVVYSIVSSSGHDRCFRI---NPQGLITLSCT 503 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 L++ + YV +VSA+D G S TA+V +N+TD+N +AP F+ Y+A V EDA +GT+V Sbjct: 504 LNYNTKHVYVFSVSASD-GMLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSV 562 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 L V ATD D G NA+I+YS+++ + +F ++ TG I T LDRE + Y Sbjct: 563 LTVLATDRDTGSNAKISYSIATLVP---------EFSVDETTGVIKTAGSLDREKVDTYR 613 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 VTA D G+P L + V I + DVNDN+PVF + Y A + ED G V +V A+DA Sbjct: 614 FEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDA 673 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 D+G N +I Y +G+F ID G+IRT K LDRE++ ++L VA D GTPP Sbjct: 674 DIGKNAQIIYSFASNGDGQGTFTIDSTQGIIRTLKPLDRETIPEYELTVVATDQGTPPGQ 733 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 ++V V + +ED+ DSPP+FE + E++P + + ++A D P + YSI Sbjct: 734 ASVKVKVILEDVKDSPPLFEKPLYEVTVPEDTPPRSPVITVKAKSQDLSPETGMMYSIVR 793 Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVN 788 G+ F + G+ + T++ LDYE+ + +Y L +RA P + + V + + D+N Sbjct: 794 GNSPQVFDINPNTGA----IQTLMKLDYET-QSEYRLTVRATLSPFFTETTVMVYLKDIN 848 Query: 789 DNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGS 848 DN PV++ F + N + P ++PAYD DV+DKL ++++ GN + LN T+G Sbjct: 849 DNTPVLEAFHMNINVQEGKVPPEARYKIPAYDPDVSDKLTFKVMEGNAKEWVTLNATSGE 908 Query: 849 MTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQF 908 ++++ +L K A ++++VTDG+ A + + +T EM+ SI + ++DM +F Sbjct: 909 LSVNKKL-IQASKPANIKIAVTDGLRTASATGSIMMTSVTTEMIQQSIQLEIDDMEVLEF 967 Query: 909 LSPLLGFFIDGLAAIIPCPKENIYIFSVQ-------DDTDVTGNILNVSFSARRPDAEVG 961 + + ++ I+ C + + +F + D + L + R+ + + Sbjct: 968 FNTAYEKLRESVSQIVKCKPDQVLMFDITSRVILPVSSADYSKTRLTIWLVLRKKNEKEA 1027 Query: 962 VAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPC-----LNFEECLTV 1016 G ++ + +R +YLHR +A+ + ++ F D++C +PC ++ +C T Sbjct: 1028 FVG----YFDASFVRYVIYLHREQIAKEVGINLMAFPDDVCSKKPCNYLKPNSYYDCNTY 1083 Query: 1017 LKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRS- 1075 F ++S V+FR + F C CP + G +C+T L G+ C S Sbjct: 1084 TYFSGEPQVLSSLKVVFRTVPVDMKFNCSCPADYRGQDCDTHLNLCYSNPCGNHGECVSV 1143 Query: 1076 --GSQCVARREGGILCQGCSIDAAYTTAVCELRARSFP 1111 G C + + G +A T C L+ R P Sbjct: 1144 EQGFYCRCKADR----VGSRCEANVTRDFCPLKPRELP 1177 Score = 458 bits (1130), Expect = e-127 Identities = 284/938 (30%), Positives = 442/938 (47%), Gaps = 96/938 (10%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDG---------DGSICRSGSQCVARREGGILCQGC 1092 F C+C G CE +T+ C + + C +G+QC+ + GG C C Sbjct: 1147 FYCRCKADRVGSRCEANVTRDFCPLKPRELPKVNQMKWNPCMNGAQCINQPGGGFGCL-C 1205 Query: 1093 SIDAAYTTAVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERH 1152 T CEL SF + F L ++ R+H+ L+F T + LLLYNG++N++ Sbjct: 1206 EDSNKADTPFCELTTLSFRDGDYAAFTALSQKWRLHISLQFTTLQSDALLLYNGQFNDKQ 1265 Query: 1153 DFLALELVSSEAGRGGGPGLRFSFSLGGGKSEIT--VEGNVGDGSWHTVEIEYFNR---- 1206 DF+A+EL G +RF+ S GG + T V+G + DG WH++ Y N+ Sbjct: 1266 DFIAIEL--------SGGQIRFTVSTGGTPASATSRVDGGLNDGRWHSLTAVYKNKHVIL 1317 Query: 1207 -----------TITMILDDCDKVLSLAGAADFGLK---YACANFTRKVLPARCEIPTETC 1252 T +I+DDC LA A FG + Y CA R + Sbjct: 1318 TSVHQTQTSPNTAIVIIDDC----KLAVAVQFGTQEGSYGCAAAKRL---------NQQA 1364 Query: 1253 HRFLDLTGPLQIGGLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPE 1312 R L LT PL +GGL ++ S + + +K + GC+ + IDHK +DL + + GT C Sbjct: 1365 ARSLQLTSPLMLGGLHSLRSEYPITSKRYTGCLRNVSIDHKRLDLAAPIWKRGTSPKCSI 1424 Query: 1313 KRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLRP 1372 K C ++PC G C++ W TY+C C E + GK C RF G +L N Sbjct: 1425 KVDFCRNSPCKRG-NCTNTWGTYLCRCPENYGGKQCDKEMKSTMRFIGQSILIKNYRTTS 1483 Query: 1373 IQLPWLNALSIRTRQ----------RDAFVMS-----IQLKSGLLHYSYNGE-TMYLPMA 1416 I+LPW +L RTR+ R F ++ +Q+ +G L Y +N + T+ L Sbjct: 1484 IKLPWSQSLMFRTRKSLGILIETRFRLCFYLNKNTLDLQVVNGRLSYQFNQQLTVNLSQL 1543 Query: 1417 TLSDGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIGG---LDTTAG 1473 + DGAWH +++ WL + VT DY + K++ + ++++GG L+T+A Sbjct: 1544 RVDDGAWHHVDVTWLRGMVRVTGDYIYQATATHQ-GEKLE--FTSELIMGGRQSLNTSAP 1600 Query: 1474 LLASDVGF-FEGCIQD-----VRIGTAQSLLNRPTVRENVRDGCQSRADCMLSICPPYSK 1527 + + F GC+ + + +Q ++ T +++V GC + C S C Sbjct: 1601 QPKAYIEEGFVGCMMGKWYFCIAVDGSQIDTSQAT-KQSVFTGCSMPSHCQSSPCLGGGT 1659 Query: 1528 CVTSWDSSTCTCEAGRVGPQCVSACELGPCGAARC-VPDQTPKGYSCACEPGYTLTTSGC 1586 CV WD+ +C C G VG +C + C+L PC C + TPKGY C C P YT C Sbjct: 1660 CVEGWDTFSCRCRPGYVGKRCTNVCDLKPCQNGNCELSSATPKGYKCKCPPQYT--GEYC 1717 Query: 1587 IESGKEECPGGWWGGS---ACGPCACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLP 1643 + C ++ S CGPC C V ++P CNK G+C+C HY+ ECL Sbjct: 1718 ETRKETPCQDKFFSASNIGLCGPCNCPVGANFNPVCNKTTGECYCNPYHYRSHKGNECLK 1777 Query: 1644 CQCYAAGSENSSCEAATGQCHCRPG------VIGRACDACANAYAEVTPNSGCEVVYDGC 1697 C C GS + C + GQC C G VIGR CD C + +E+T GC V+ C Sbjct: 1778 CNCEEIGSLSLQCRVSDGQCPCIKGSSTGARVIGRRCDRCEDHQSEITAGKGCVVINTSC 1837 Query: 1698 PRSFAGGVWWPRTKFGVETITDCPPGSSGRATRTCDETKDVPWQDPDMFNCTTATFYQLR 1757 PRS A +WW R F CP G+SG A R CD+ K WQ PD+ +C + +F LR Sbjct: 1838 PRSIAEDIWWKRGAFDKTAEQKCPFGASGTARRICDKNKG--WQKPDLMDCVSNSFLNLR 1895 Query: 1758 KQLHKIETGELTMNTFVGVRVAADLSTACANTPRLYGADVVVAEGILLELMDYELRQAGL 1817 K+L ++E G+L + + + +A L A RLY D+ +A + L DYE +Q Sbjct: 1896 KKLKRLEEGKLLWSPSIAMDLARQLDLAITLATRLYPNDIDIALKAITVLFDYESQQNES 1955 Query: 1818 NLTHSQDKDYVRNLLKSTNTILNVEYEREWKRIRELTGHGAELLVQKFDEYIAVLAESQH 1877 L +++ ++ + L++S + + N E + W ++ + A+L+ +K + + LA + Sbjct: 1956 TLVSAKNHEFAQILVQSASMLFNAENKNVWSVVQRNSAGTADLM-EKMENFSGTLANNLA 2014 Query: 1878 DTYTSPFEIVTKDVVISVDTVTSESIYGFEPTQLNRLN 1915 + + + ++ +T + P + N Sbjct: 2015 HLKRARYRRNVESIIPPYTVITPNILMELHPVTIRNFN 2052 Score = 371 bits (912), Expect = e-100 Identities = 264/841 (31%), Positives = 414/841 (49%), Gaps = 55/841 (6%) Query: 18 DHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXX 77 ++ P F Q +ASV E A GT V T+ A+D D G N + Y+ ++P Sbjct: 15 NNPPQFSRLQEDASVSEDAEVGTVVATVSASDPDSGSNGMIRYS--------MSPSQNLM 66 Query: 78 XXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIH 137 F ID +G + T+ LDRE + R+ VKA D P L + Sbjct: 67 SATY--------FSIDQITGVITTKRGLDREFLDRHFFRVKAEDGGEP---SLEGYMDLT 115 Query: 138 VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN-T 196 +N++D NDN P F Y + ED S+ D + ++A+DAD G+N ++Y I+ + Sbjct: 116 INVLDVNDNGPIFERNIYAADIPEDKSIGD--FVLAVRASDADSGSNGEVKYCILNSDGD 173 Query: 197 QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256 FSI +SG V+++K LD E+V +Y L ++AQD G+P RS T + I + DVND P+ Sbjct: 174 NSAFSIGEVSGAVTVMKKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQ 233 Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316 F ++ ++ E+VP+ + V+A D D+G N E+ + + +GN +I+ +G Sbjct: 234 FSKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFFEIV----SGNDMNFFSINRING 289 Query: 317 WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376 V +LD E + LLVTA D G P T F+ ++ + Sbjct: 290 EVRVKQKLDYEMIGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIP 349 Query: 377 EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436 E+ G + A D+D+ + EIT + + G I++ + LD ++ + Sbjct: 350 ENYAVGQEFYRVQA--YDKDHGTNGEITFSFMQNDLPFSINENTGGISIKEELDREKVPK 407 Query: 437 YVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494 + + A D G + TA + I + D N+ P F Y S+ E++ GT+VL V A Sbjct: 408 FTFGIKARDKGVPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAI 467 Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554 D D G + YS+ S + HD+ F INPQ G IT + L+ T Y+ +V+A Sbjct: 468 DPDSG-PTNVVYSIVSS------SGHDRCFRINPQ-GLITLSCTLNYNTKHVYVFSVSAS 519 Query: 555 DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614 DG LS T V ++V D N + P FK++ Y+A + EDA +GTSV V ATD D G N Sbjct: 520 DG---MLSSTALVYVNVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNA 576 Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674 +I Y + E F +D +GVI+T +LDRE V T+ + A D G P + V+ Sbjct: 577 KISYSIATLVPE---FSVDETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKAKSFVY 633 Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-KGGDDSN 733 I I D+ND+ PVF + E+ G + E+ A D D G NA + YS GD Sbjct: 634 IHIADVNDNDPVFLKPSYEAKVREDIRPGGRVIEVSASDADIGKNAQIIYSFASNGDGQG 693 Query: 734 SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDN 790 +F++++ QG + T+ LD E+ +YEL + A +PP V+V++++ DV D+ Sbjct: 694 TFTIDSTQGI----IRTLKPLDRET-IPEYELTVVATDQGTPPGQASVKVKVILEDVKDS 748 Query: 791 APVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNNANLILLNETTGS 848 P+ + +D P P V A D++ + + Y I+ GN+ + +N TG+ Sbjct: 749 PPLFEKPLYEVTVPEDTPPRSPVITVKAKSQDLSPETGMMYSIVRGNSPQVFDINPNTGA 808 Query: 849 M 849 + Sbjct: 809 I 809 Score = 309 bits (758), Expect = 9e-82 Identities = 239/756 (31%), Positives = 349/756 (46%), Gaps = 42/756 (5%) Query: 145 DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ---FS 201 +N PQFS SV ED V V+A + A+D D G+N IRY++ M FS Sbjct: 15 NNPPQFSRLQEDASVSEDAEV--GTVVATVSASDPDSGSNGMIRYSMSPSQNLMSATYFS 72 Query: 202 IDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261 ID ++G ++ + LD E + + ++A+DGG PS L IN+ DVNDN P F ++ Sbjct: 73 IDQITGVITTKRGLDREFLDRHFFRVKAEDGGEPSLEGYMDLTINVLDVNDNGPIFERNI 132 Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321 + + E+ IG ++ V+A DAD G N E+ Y + + D + +I SG V Sbjct: 133 YAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDNSA---FSIGEVSGAVTVM 189 Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381 +LDRE Y L V A D G+PPRSAT T F Y + ED P Sbjct: 190 KKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPV 249 Query: 382 GTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL 439 V T+ ATD D+ + + +EI GN FSI NG + V Q LD++ + L Sbjct: 250 NQLVTTVRATDCDQGSNGEVFFEIVSGNDMNFFSINRINGE--VRVKQKLDYEMIGVFNL 307 Query: 440 TVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497 V+A D G + V I + D N+ AP F ++ + + E+ +G V A D D Sbjct: 308 LVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRVQAYDKD 367 Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG 557 G N +IT+S +D F IN TG I+ + LDRE + + + ARD G Sbjct: 368 HGTNGEITFSF---------MQNDLPFSINENTGGISIKEELDREKVPKFTFGIKARDKG 418 Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617 VP T + I+++D+NDN P F Q+ Y +I E++ GTSV QV A D D G + Sbjct: 419 VPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSGPT-NVV 477 Query: 618 YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 Y + + F I+P G+I + L+ + + A DG SST +V++ + Sbjct: 478 YSIVSSSGHDRCFRINP-QGLITLSCTLNYNTKHVYVFSVSASDG---MLSSTALVYVNV 533 Query: 678 EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL 737 D N P F+ + + E++ +GT++ + A D D G NA + YSI FS+ Sbjct: 534 TDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSI--ATLVPEFSV 591 Query: 738 ETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVM 794 + G K T LD E Y + A P L V I + DVNDN PV Sbjct: 592 DETTGVIK----TAGSLDREKV-DTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVF 646 Query: 795 KDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQ--YRILS-GNNANLILLNETTGSM-T 850 +D P G V A DAD+ Q Y S G+ ++ T G + T Sbjct: 647 LKPSYEAKVREDIRPGGRVIEVSASDADIGKNAQIIYSFASNGDGQGTFTIDSTQGIIRT 706 Query: 851 LSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886 L P +P+ V+ G +A +++ V L Sbjct: 707 LKPLDRETIPEYELTVVATDQGTPPGQASVKVKVIL 742 Score = 287 bits (705), Expect = 2e-75 Identities = 216/708 (30%), Positives = 338/708 (47%), Gaps = 48/708 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I +LD ND +P F + Y A++RE V T++ATD D G N EV + E+V+ + Sbjct: 221 KITLLDVNDCTPQFSKKVYSATIREDVPVNQLVTTVRATDCDQGSNGEVFF--EIVSGND 278 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 +N F I+ +G + + LD E + + +LV A D+ P Sbjct: 279 MN-----------------FFSINRINGEVRVKQKLDYEMIGVFNLLVTAQDKGQPF--- 318 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L + T+ + +ID NDN PQF + + E+ +V +++A D D G N I + Sbjct: 319 LYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQE--FYRVQAYDKDHGTNGEITF 376 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 + + + FSI+ +G +S+ + LD E+V + I+A+D G P + T Q+ I + D Sbjct: 377 SFM--QNDLPFSINENTGGISIKEELDREKVPKFTFGIKARDKGVPFKEGTAQITITLLD 434 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 +NDN P+F + S++EN G S+++V+A D D G + Y++ +G+ D Sbjct: 435 INDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSG-PTNVVYSIVSS--SGH-DRCF 490 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 I+P+ G + S L+ T+ Y V+A+DG S+TA F Sbjct: 491 RINPQ-GLITLSCTLNYNTKHVYVFSVSASDG---MLSSTALVYVNVTDSNTHAPEFKRR 546 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 Y E+ ED GT V+T+ ATD D + + FS+ G+I A L Sbjct: 547 SYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSIATLVPEFSVDETT--GVIKTAGSL 604 Query: 430 DFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 D ++ Y V+ATD G + V I+I D N+ PVF Y A V ED G Sbjct: 605 DREKVDTYRFEVTATDHGIPQLKAKSFVYIHIADVNDNDPVFLKPSYEAKVREDIRPGGR 664 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 V+ VSA+D+D+G NAQI YS +S + F I+ G I T K LDRET+ Y Sbjct: 665 VIEVSASDADIGKNAQIIYSFASNGDGQGT------FTIDSTQGIIRTLKPLDRETIPEY 718 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 LTV A D G P + V++ + DV D+ P+F++ LY + ED + V V A Sbjct: 719 ELTVVATDQGTPPGQASVKVKVILEDVKDSPPLFEKPLYEVTVPEDTPPRSPVITVKAKS 778 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 D+ + Y + + F I+P +G I+T LD E+ + + L + P Sbjct: 779 QDLSPETGMMYSI-VRGNSPQVFDINPNTGAIQTLMKLDYETQSEYRL---TVRATLSPF 834 Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 + V + ++DIND+ PV E+ + + E +I A+DPD Sbjct: 835 FTETTVMVYLKDINDNTPVLEAFHMNINVQEGKVPPEARYKIPAYDPD 882 Score = 239 bits (585), Expect = 8e-61 Identities = 159/432 (36%), Positives = 222/432 (51%), Gaps = 21/432 (4%) Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523 N P F ASV EDA +GT V VSA+D D G N I YS+S + + + Sbjct: 15 NNPPQFSRLQEDASVSEDAEVGTVVATVSASDPDSGSNGMIRYSMSPSQNLMSATY---- 70 Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583 F I+ TG ITT + LDRE + + V A DGG PSL D+ I+V+DVNDN P+F++ Sbjct: 71 FSIDQITGVITTKRGLDREFLDRHFFRVKAEDGGEPSLEGYMDLTINVLDVNDNGPIFER 130 Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK 643 +Y A+I ED +G V V A+DAD G NG + Y + D + +F I SG + K Sbjct: 131 NIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDNSAFSIGEVSGAVTVMK 190 Query: 644 ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703 LDRE V T+ L+ A D G PP+S+TV V I + D+ND P F + I E+ P+ Sbjct: 191 KLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPVN 250 Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY 763 + +RA D D+G N V + I G+D N FS+ G E+ LDYE + Sbjct: 251 QLVTTVRATDCDQGSNGEVFFEIVSGNDMNFFSINRING----EVRVKQKLDYEM-IGVF 305 Query: 764 ELVIRA---ASPPLWNDVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFPVG-PFGRVP 817 L++ A P L+N V+I + DVNDNAP V FQ + + + VG F RV Sbjct: 306 NLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMI---PENYAVGQEFYRVQ 362 Query: 818 AYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN-TNVPKLATMEVSVTD-GVNE 875 AYD D + N +NE TG +++ +L+ VPK T + D GV Sbjct: 363 AYDKDHGTNGEITFSFMQNDLPFSINENTGGISIKEELDREKVPKF-TFGIKARDKGVPF 421 Query: 876 IKAMMQLSVRLI 887 + Q+++ L+ Sbjct: 422 KEGTAQITITLL 433 Score = 235 bits (574), Expect = 2e-59 Identities = 190/637 (29%), Positives = 282/637 (44%), Gaps = 25/637 (3%) Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 R +N P+F SVSE+ +G + V A D D G N + Y+M+ + Sbjct: 11 RAPTNNPPQFSRLQEDASVSEDAEVGTVVATVSASDPDSGSNGMIRYSMSPSQNLMSATY 70 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 +ID +G + T LDRE ++ V A DGG+P F Sbjct: 71 -FSIDQITGVITTKRGLDREFLDRHFFRVKAEDGGEPSLEGYMDLTINVLDVNDNGPIFE 129 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITS-QNGRGLITVA 426 Y ++ ED+ G V+ + A+DAD + + N+ G S S G +TV Sbjct: 130 RNIYAADIPEDKSIGDFVLAVRASDADSGSNGEVKYCILNSDGDNSAFSIGEVSGAVTVM 189 Query: 427 QPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 + LD ++ Y L V A D G RS T V+I + D N+ P F Y+A++ ED P+ Sbjct: 190 KKLDREKVPTYTLQVQAQDQGNPPRSATVTVKITLLDVNDCTPQFSKKVYSATIREDVPV 249 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRET 543 V V ATD D G N ++ + E V+ +D F IN G + + LD E Sbjct: 250 NQLVTTVRATDCDQGSNGEVFF--------EIVSGNDMNFFSINRINGEVRVKQKLDYEM 301 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 + + L VTA+D G P L + T V+I+++DVNDN P F + I E+ VG +V Sbjct: 302 IGVFNLLVTAQDKGQPFLYNQTTVDIALIDVNDNAPQFVSSHFQTMIPENYAVGQEFYRV 361 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 A D D G NG I + D F I+ +G I + LDRE V A D G Sbjct: 362 QAYDKDHGTNGEITFSFMQNDL---PFSINENTGGISIKEELDREKVPKFTFGIKARDKG 418 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 P + T + I + DIND+PP F + I+ENS GT++ +++A DPD GP VV+ Sbjct: 419 VPFKEGTAQITITLLDINDNPPKFSQEEYHTSIAENSRWGTSVLQVKAIDPDSGPTNVVY 478 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTM-VDLDYESPRKKYELVIRAASPPLWNDVRVEI 782 + F + QG L+T+ L+Y + + Y + A+ L + V + Sbjct: 479 SIVSSSGHDRCFRINP-QG-----LITLSCTLNYNT-KHVYVFSVSASDGMLSSTALVYV 531 Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILL 842 VTD N +AP K +D V A D D + + Sbjct: 532 NVTDSNTHAPEFKRRSYSAEVKEDASLGTSVLTVLATDRDTGSNAKISYSIATLVPEFSV 591 Query: 843 NETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKA 878 +ETTG + + L+ EV+ TD G+ ++KA Sbjct: 592 DETTGVIKTAGSLDREKVDTYRFEVTATDHGIPQLKA 628 Score = 74.1 bits (174), Expect = 5e-11 Identities = 48/166 (28%), Positives = 91/166 (54%), Gaps = 20/166 (12%) Query: 2159 NATGVGKKMYRSLSGIRLKKPIRLQIWLDINRETFGSRTNPQCVHWS----TLRGSGEWS 2214 N+ V KM + ++L +PI + + NR+ +R+ CV W+ RG G WS Sbjct: 2142 NSDVVSVKM-PGMEDVQLAEPIHITFY---NRQV--NRSEYLCVFWNYSVPNTRGGG-WS 2194 Query: 2215 RVGCHTEIDYDWSPYSEEPLLINCTCNHLSTFAVLVDEVDVEFIPEPSLLESVTSYTAFS 2274 GC I +W+ + C CNH+++FAVL D +++EF P+ + + +Y + Sbjct: 2195 TNGCR-RIAINWTHTT-------CACNHMTSFAVLSD-LNLEFPPQVAFALRIGTYIGIA 2245 Query: 2275 ISLPLLLTSWAALCLIRGGAATVSNSIHKHLIFSVFMAELLYLIAL 2320 +S+ +LL ++ + +RG + +N IHK+L+ ++ +AE+++L + Sbjct: 2246 VSVAILLIAFVSFVCLRGLKKSNANDIHKNLVAAIVIAEIIFLAGI 2291 >UniRef50_Q16QV0 Cluster: Cadherin; n=10; Eukaryota|Rep: Cadherin - Aedes aegypti (Yellowfever mosquito) Length = 2413 Score = 491 bits (1211), Expect = e-136 Identities = 401/1390 (28%), Positives = 636/1390 (45%), Gaps = 117/1390 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 ++V D ND++P+FE Y S+ E G++++ L A D D G N ++ Y++ D + Sbjct: 557 LHVQDENDNTPMFESNPYSFSLAENIEKGSSIMKLTARDSDSGSNGDIRYSLSTEVGDIV 616 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N +F ID +G + T LD+EK Y V ATD P + Sbjct: 617 N-----------------IFDIDAYTGWITTLVPLDKEKREDYKFQVIATDNGQP---KH 656 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+ T+ + + D ND P F E Y SV ED V+ +I+ TD DV + I Y Sbjct: 657 STRTTVIIRLKDYNDCPPTFKESHYKASVSED--ALPGTVVLQIETTDKDVDLKTNIEYY 714 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 II G+ QF I + SG+V +VKTLD E + Y L + DG S +N + + + D Sbjct: 715 IISGDPLSQFQIKN-SGEVFVVKTLDRESISQYELGVIVTDGKFTSTANIS---VTVLDA 770 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P ++E +SE V G ++++QA D DE N+ L + +T GN Sbjct: 771 NDNPPYCLKYRYREQLSEGVHPGTYVLQIQANDIDEPANSRLRFYLT-----GNGAEDFN 825 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 +D SG + T+ QLDRETQ+K+ L+ D P ++ F Sbjct: 826 LDKDSGQLKTARQLDRETQSKFHLVAHVQDRDHPGWECSSQIEITITDLNDNPPDFSMNP 885 Query: 371 YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 Y V L ED GT V + ATDAD + ++ Y + R F I +G ++T+A+P Sbjct: 886 YSVTLPEDAEVGTLVTKIHATDADIGINRKIKYSFID-SYRDHFKIAPDSG--IVTLAKP 942 Query: 429 LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD + + Y LTV ATD G S++A + +N+ D N+ P F + Y ASV E++ IGT Sbjct: 943 LDREVKAVYNLTVRATDQGKPSLSNSAFLVVNVQDINDNPPEFTSKHYFASVLENSSIGT 1002 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 VL V AT D GINA+ITYS+ NE ++F ++ +TG + ++D E Sbjct: 1003 EVLRVLATSKDTGINAEITYSIIG--GNE-----HRKFAMHNKTGVLYLADVVDYERAKD 1055 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y LT+ A DGG P LS+ V ISV D NDN P F YTA I EDA G + Q+ A Sbjct: 1056 YFLTIQAVDGGTPPLSNLATVNISVADCNDNPPQFTANSYTATIREDAQKGDKMLQIRAN 1115 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D D G N R+ Y ++ DR G F I+ +G I LDRES++++ L+ A D G+P Sbjct: 1116 DMDSGENSRVSYRIERGDRM-GQFDIEEDTGYISVAGTLDRESISSYVLEVQARDHGSPS 1174 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH-YS 725 S+ V+V+I+I D ND+PP+F S+ T + E+ IG T+ + D D PNA + + Sbjct: 1175 LSTYVLVNIEISDANDNPPLFTSNNYTAVVQEDKQIGFTLLKFEVTDADAAPNAAPYTFD 1234 Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEI 782 ++ G+D +F +E + G ++ + Y L IR SPPL++D V I Sbjct: 1235 VRSGNDGGAFRIE-QDG-----ILRTASRFNSKIKDTYLLGIRVFDNGSPPLYSDTWVSI 1288 Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRIL--SG---NNA 837 V + + PV+ + N+++D +P G G+V A D D D L + + +G + Sbjct: 1289 KVIEESQYPPVITPLDVSINSFQDEYPGGVIGKVYATDQDQYDTLTFSLAPTAGVLYSPM 1348 Query: 838 NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSIT 897 NL ++ G + P+L+ ++ ++V+DG +++++V L+T+EML NSI Sbjct: 1349 NLFNISRNDGVLYAFPRLDVGDYRV---NITVSDGKFSSYTIVKVAVELVTDEMLANSIV 1405 Query: 898 VRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQ---DDTDVTGNILNVSFSAR 954 +R ++ E F+ FI + + C ++I I SVQ DD ++ + L Sbjct: 1406 IRFTKISPESFILSHRKGFIRSVRNSMGCKIKDIIIISVQKSNDDINLIHHRLRRELGTL 1465 Query: 955 RP-DAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEEC 1013 D V +YS +R+ + + + +Q+ + C+ C++ EC Sbjct: 1466 HDLDVLFTVRKGQLGYYSAYEIRKAIDDNLEEIEDATKLQIDEVVKSKCLPNFCIH-GEC 1524 Query: 1014 LTVLKFG-NASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSI 1072 L +++D F V C C EG+ G C+ + + S + Sbjct: 1525 EDKLVLDPKIVNPISTDVTSFVSARHVHKMECSCKEGYGGDKCQHAVNECSKSPCPNYKN 1584 Query: 1073 C-----RSGSQCVA-RREGGILC----QGCSIDAAYTTA-VCELRARSFP---VSSFLTF 1118 C G C+ R G C C+ + YT +S+ V + Sbjct: 1585 CIPDSSDQGYHCICPERFAGPKCDRDISKCNDETCYTPRNPVSFSGKSYAQYRVEKEIAK 1644 Query: 1119 PGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRGGGPGLRFSFSL 1178 L+ + + L+++ Q T ++ G+ D+ LE+V+ +++ F L Sbjct: 1645 KNLEDQLMLSLRIR-TVQPTGNIMFSAGKV----DYNILEIVNGV--------VQYRFDL 1691 Query: 1179 GGGKSEITVEG-NVGDGSWHTVEIEYFNRTITMILDDCDKVLSLAGAAD--FGLKYACAN 1235 G G+ ++V V DG WH V +E + + +I+D+ A + L+ Sbjct: 1692 GSGEGMVSVTSIFVSDGLWHEVRLERESNSARVIVDNKHVASGNAPGVNGVLNLQSDDIF 1751 Query: 1236 FTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNKDFVGCISDFYIDHKFI 1295 F +V + E R G + L +P + V + F Sbjct: 1752 FGAEVKQHPTVLGFEDIQR--GYMGCMDDIKLSKVPVPLHMNGASSVASLRRFANVEFSC 1809 Query: 1296 DLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLW-DTYICDCKEGHTGKDCADSTGP 1354 D +S + G C + PC+NG C+D+ + C C +G C + P Sbjct: 1810 DASSILVPLGV----------CGTQPCWNGGTCTDIGAGNFECLCHSRFSGPFCKEDLDP 1859 Query: 1355 ----PWRFGG 1360 P +GG Sbjct: 1860 CASSPCLYGG 1869 Score = 344 bits (846), Expect = 2e-92 Identities = 248/814 (30%), Positives = 399/814 (49%), Gaps = 44/814 (5%) Query: 97 GALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT 156 G L +LDRE + + + A +SP ++ T+HV D+NDN P F Y+ Sbjct: 519 GELRLAKTLDRELKDVHLIAILAETDSSPPLTAVTDV-TLHVQ--DENDNTPMFESNPYS 575 Query: 157 VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG--GNTQMQFSIDSLSGDVSLVKT 214 S+ E+I + I K+ A D+D G+N IRY++ G+ F ID+ +G ++ + Sbjct: 576 FSLAENIEKGSS--IMKLTARDSDSGSNGDIRYSLSTEVGDIVNIFDIDAYTGWITTLVP 633 Query: 215 LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY 274 LD E+ Y+ + A D G P S T ++I ++D ND P F S ++ SVSE+ G Sbjct: 634 LDKEKREDYKFQVIATDNGQPKHSTRTTVIIRLKDYNDCPPTFKESHYKASVSEDALPGT 693 Query: 275 SIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQL 334 +++++ D D + + Y + D + SG V+ LDRE+ ++Y+L Sbjct: 694 VVLQIETTDKDVDLKTNIEYYIISGDPLSQFQIK-----NSGEVFVVKTLDRESISQYEL 748 Query: 335 LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394 V TDG ++TA + +Y +L+E PGT V+ + A D D Sbjct: 749 GVIVTDG---KFTSTANISVTVLDANDNPPYCLKYRYREQLSEGVHPGTYVLQIQANDID 805 Query: 395 E--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT--VSATDSGGRS 450 E ++RL + +TG F++ +G+ + A+ LD + + ++ L V D G Sbjct: 806 EPANSRLRFYLTGNGAED-FNLDKDSGQ--LKTARQLDRETQSKFHLVAHVQDRDHPGWE 862 Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510 ++ ++I ITD N+ P F PY+ ++ EDA +GT V + ATD+D+GIN +I YS Sbjct: 863 CSSQIEITITDLNDNPPDFSMNPYSVTLPEDAEVGTLVTKIHATDADIGINRKIKYSF-- 920 Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570 + + F I P +G +T K LDRE + Y LTV A D G PSLS++ + ++ Sbjct: 921 ------IDSYRDHFKIAPDSGIVTLAKPLDREVKAVYNLTVRATDQGKPSLSNSAFLVVN 974 Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630 V D+NDN P F + Y A+++E++ +GT V +V AT D G+N I Y + E F Sbjct: 975 VQDINDNPPEFTSKHYFASVLENSSIGTEVLRVLATSKDTGINAEITYSI-IGGNEHRKF 1033 Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690 + +GV+ +D E + L A+DGGTPP S+ V+I + D ND+PP F ++ Sbjct: 1034 AMHNKTGVLYLADVVDYERAKDYFLTIQAVDGGTPPLSNLATVNISVADCNDNPPQFTAN 1093 Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750 T I E++ G + +IRA+D D G N+ V Y I+ GD F +E D + Sbjct: 1094 SYTATIREDAQKGDKMLQIRANDMDSGENSRVSYRIERGDRMGQFDIE----EDTGYISV 1149 Query: 751 MVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVM--KDFQIIFNNYK 805 LD ES Y L ++A SP L V V I ++D NDN P+ ++ + K Sbjct: 1150 AGTLDRES-ISSYVLEVQARDHGSPSLSTYVLVNIEISDANDNPPLFTSNNYTAVVQEDK 1208 Query: 806 DC-FPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLAT 864 F + F A A + + SGN+ + E G + + + N+ + Sbjct: 1209 QIGFTLLKFEVTDADAAPNAAPYTFDVRSGNDGGAFRI-EQDGILRTASRFNSKIKDTYL 1267 Query: 865 MEVSVTD-GVNEIKAMMQLSVRLITEEMLLNSIT 897 + + V D G + + +S+++I E IT Sbjct: 1268 LGIRVFDNGSPPLYSDTWVSIKVIEESQYPPVIT 1301 Score = 289 bits (710), Expect = 6e-76 Identities = 254/878 (28%), Positives = 401/878 (45%), Gaps = 73/878 (8%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 H ++V+D ND+ P FE Y + E A+ G V + A+D D + + YTI Sbjct: 141 HVWVSVMDMNDNPPKFEQPSYTCVLSEHATRGQFVTVVSASDPDYIDHDRLTYTI--AQG 198 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVL-VKATDQASPV 126 + L D I+ SG ++T ++ T+L V TD Sbjct: 199 NELQTYD-----------------INPVSG-IITLVNMQNFAEKHVTILNVSVTDGV--- 237 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 +S + + I+ N + P F Y V V+E+ ++ +KA D D G Sbjct: 238 ---YTSFTRVKITILPANLHNPTFEHLFYDVKVNENQLA--GRLVTTVKAQDKDFGEFGR 292 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 + Y II Q FSID G++ K LD E+ + Y + I A D G R+ T + +N Sbjct: 293 LTYFIISDEIQEYFSIDKDKGEIVTKKKLDREERKLYEVPIMAMDSG--GRAGFTTVRVN 350 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + D NDN P F ++ + N+ + RV+A D+D+ NA + Y++ D +G + Sbjct: 351 VGDENDNPPVFLLREYKALIQGNLTTNTTFFRVKAVDSDDNQNAVVKYSIFDSQNSGIKE 410 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 L ID +G +Y R +Q + A DGG P F Sbjct: 411 L-FGIDENTGGIYLRKSAVRWENQLFQFFIRANDGGVPSLYTDVPIDIYIMSSAENPPVF 469 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGN-TRGRFSITSQNGRGLITV 425 + + L+E PGT + L + + Y I +FSI N G + + Sbjct: 470 EKKEKLLFLSESSLPGTVITRLKLSG---NVTAKYRILSDELEEPQFSI---NNVGELRL 523 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAP 483 A+ LD + + +++ + A TA+ V +++ D N+ P+FE+ PY+ S+ E+ Sbjct: 524 AKTLDRELKDVHLIAILAETDSSPPLTAVTDVTLHVQDENDNTPMFESNPYSFSLAENIE 583 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 G++++ ++A DSD G N I YSLS+E+ + F I+ TG ITT LD+E Sbjct: 584 KGSSIMKLTARDSDSGSNGDIRYSLSTEVGDIV-----NIFDIDAYTGWITTLVPLDKEK 638 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 Y V A D G P S T V I + D ND P FK+ Y A++ EDAL GT V Q+ Sbjct: 639 REDYKFQVIATDNGQPKHSTRTTVIIRLKDYNDCPPTFKESHYKASVSEDALPGTVVLQI 698 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 TD DV L I Y + D F I SG + K LDRES++ ++L + DG Sbjct: 699 ETTDKDVDLKTNIEYYIISGD-PLSQFQI-KNSGEVFVVKTLDRESISQYELGVIVTDG- 755 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 +ST + + + D ND+PP +SE GT + +I+A+D DE N+ + Sbjct: 756 --KFTSTANISVTVLDANDNPPYCLKYRYREQLSEGVHPGTYVLQIQANDIDEPANSRLR 813 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV--IRAASPPLWN-DVRV 780 + + G+ + F+L+ D +L T LD E+ + K+ LV ++ P W ++ Sbjct: 814 FYLT-GNGAEDFNLD----KDSGQLKTARQLDRET-QSKFHLVAHVQDRDHPGWECSSQI 867 Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFP----VGPF-GRVPAYDAD--VTDKLQYRILS 833 EI +TD+NDN P DF + N Y P VG ++ A DAD + K++Y + Sbjct: 868 EITITDLNDNPP---DFSM--NPYSVTLPEDAEVGTLVTKIHATDADIGINRKIKYSFID 922 Query: 834 GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + + + +G +TL+ L+ V + + V TD Sbjct: 923 SYRDHFKIAPD-SGIVTLAKPLDREVKAVYNLTVRATD 959 Score = 267 bits (655), Expect = 3e-69 Identities = 223/780 (28%), Positives = 360/780 (46%), Gaps = 44/780 (5%) Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS 164 LD E+ Y +L++ATD S VS + + V + D ND P+ + +Y ++V E Sbjct: 8 LDYEQRQSYELLIRATDSVSGVS----AEVPVSVLVQDVNDCPPEIEQDSYNITVSERAQ 63 Query: 165 VTDNPVIAKIKATDADVGANSAIRYAII--GGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222 I K++A D D G N + YA+ NT F +D G + L K+LD+E + Sbjct: 64 F--GTAILKVQAKDNDTGINQVVTYALQTDSKNTSEYFHMDPTDGVIYLKKSLDHETLSH 121 Query: 223 YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY 282 + + A D G PS S+T + +++ D+NDN P+F + +SE+ G + V A Sbjct: 122 HHFTVIASDKGVPSLSSTAHVWVSVMDMNDNPPKFEQPSYTCVLSEHATRGQFVTVVSAS 181 Query: 283 DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL-VTATDG 341 D D + LTYT+ GN I+P SG + T + + +L V+ TDG Sbjct: 182 DPDYIDHDRLTYTIAQ----GNELQTYDINPVSG-IITLVNMQNFAEKHVTILNVSVTDG 236 Query: 342 GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRL 399 ++ F Y+V++ E++ G V T+ A D D E RL Sbjct: 237 ---VYTSFTRVKITILPANLHNPTFEHLFYDVKVNENQLAGRLVTTVKAQDKDFGEFGRL 293 Query: 400 HYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINI 459 Y I + FSI G I + LD ++ + Y + + A DSGGR+ V++N+ Sbjct: 294 TYFIISDEIQEYFSIDKDKGE--IVTKKKLDREERKLYEVPIMAMDSGGRAGFTTVRVNV 351 Query: 460 TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAH 519 D N+ PVF Y A + + TT V A DSD NA + YS+ + N + Sbjct: 352 GDENDNPPVFLLREYKALIQGNLTTNTTFFRVKAVDSDDNQNAVVKYSI-FDSQNSGI-- 408 Query: 520 HDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP 579 + F I+ TG I K R + + A DGGVPSL ++I ++ +N P Sbjct: 409 -KELFGIDENTGGIYLRKSAVRWENQLFQFFIRANDGGVPSLYTDVPIDIYIMSSAENPP 467 Query: 580 VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639 VF+++ + E +L GT ++++ + N Y + + EE F I+ G + Sbjct: 468 VFEKKEKLLFLSESSLPGTVITRLKLSG-----NVTAKYRILSDELEEPQFSINNV-GEL 521 Query: 640 RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699 R K LDRE H + +A +PP ++ V + ++D ND+ P+FES+ +F ++EN Sbjct: 522 RLAKTLDRELKDVHLIAILAETDSSPPLTAVTDVTLHVQDENDNTPMFESNPYSFSLAEN 581 Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSI--KGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757 G++I ++ A D D G N + YS+ + GD N F ++ G + T+V LD E Sbjct: 582 IEKGSSIMKLTARDSDSGSNGDIRYSLSTEVGDIVNIFDIDAYTG----WITTLVPLDKE 637 Query: 758 SPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG 814 R+ Y+ + A P V I + D ND P K+ + +D P Sbjct: 638 K-REDYKFQVIATDNGQPKHSTRTTVIIRLKDYNDCPPTFKESHYKASVSEDALPGTVVL 696 Query: 815 RVPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 ++ D DV K ++Y I+SG+ + + + +G + + L+ + V VTDG Sbjct: 697 QIETTDKDVDLKTNIEYYIISGDPLSQFQI-KNSGEVFVVKTLDRESISQYELGVIVTDG 755 Score = 257 bits (629), Expect = 4e-66 Identities = 224/853 (26%), Positives = 369/853 (43%), Gaps = 60/853 (7%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72 V D ND P E Y +V E A GT +L ++A D D G N V Y ++ + +T Sbjct: 39 VQDVNDCPPEIEQDSYNITVSERAQFGTAILKVQAKDNDTGINQVVTYALQTDSKNT--- 95 Query: 73 EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132 + F +D G + + SLD E ++ + V A+D+ P LSS Sbjct: 96 --------------SEYFHMDPTDGVIYLKKSLDHETLSHHHFTVIASDKGVP---SLSS 138 Query: 133 TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192 TA + V+++D NDN P+F + +YT + E T + + A+D D + + Y I Sbjct: 139 TAHVWVSVMDMNDNPPKFEQPSYTCVLSE--HATRGQFVTVVSASDPDYIDHDRLTYTIA 196 Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252 GN + I+ +SG ++LV ++ + L + DG ++ T++ I I N Sbjct: 197 QGNELQTYDINPVSGIITLVNMQNFAEKHVTILNVSVTDG---VYTSFTRVKITILPANL 253 Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312 + P F + V+EN G + V+A D D G LTY + + + +ID Sbjct: 254 HNPTFEHLFYDVKVNENQLAGRLVTTVKAQDKDFGEFGRLTYFIISDE----IQEYFSID 309 Query: 313 PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE 372 G + T +LDRE + Y++ + A D G R+ T F+ +Y+ Sbjct: 310 KDKGEIVTKKKLDREERKLYEVPIMAMDSGG--RAGFTTVRVNVGDENDNPPVFLLREYK 367 Query: 373 VELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRG---RFSITSQNGRGLITVAQ 427 + + T + A D+D++ + Y I G F I G G+ Sbjct: 368 ALIQGNLTTNTTFFRVKAVDSDDNQNAVVKYSIFDSQNSGIKELFGIDENTG-GIYLRKS 426 Query: 428 PLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 + + + + + + A D G S + I I + PVFE + E + G Sbjct: 427 AVRW-ENQLFQFFIRANDGGVPSLYTDVPIDIYIMSSAENPPVFEKKEKLLFLSESSLPG 485 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 T + T + N Y + +S+E + QF IN G + K LDRE Sbjct: 486 TVI-----TRLKLSGNVTAKYRI---LSDEL---EEPQFSIN-NVGELRLAKTLDRELKD 533 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 +L+ + A P L+ TDV + V D NDN P+F+ Y+ ++ E+ G+S+ ++ A Sbjct: 534 VHLIAILAETDSSPPLTAVTDVTLHVQDENDNTPMFESNPYSFSLAENIEKGSSIMKLTA 593 Query: 606 TDADVGLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 D+D G NG I Y L + + F ID +G I T LD+E + + +A D G Sbjct: 594 RDSDSGSNGDIRYSLSTEVGDIVNIFDIDAYTGWITTLVPLDKEKREDYKFQVIATDNGQ 653 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 P S+ V I+++D ND PP F+ +SE++ GT + +I D D + Y Sbjct: 654 PKHSTRTTVIIRLKDYNDCPPTFKESHYKASVSEDALPGTVVLQIETTDKDVDLKTNIEY 713 Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILV 784 I GD + F ++ + E+ + LD ES +YEL + + + + V Sbjct: 714 YIISGDPLSQFQIK-----NSGEVFVVKTLDRES-ISQYELGVIVTDGKFTSTANISVTV 767 Query: 785 TDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRI-LSGNNANLILLN 843 D NDN P ++ + P ++ A D D + R L+GN A L+ Sbjct: 768 LDANDNPPYCLKYRYREQLSEGVHPGTYVLQIQANDIDEPANSRLRFYLTGNGAEDFNLD 827 Query: 844 ETTGSMTLSPQLN 856 + +G + + QL+ Sbjct: 828 KDSGQLKTARQLD 840 Score = 218 bits (532), Expect = 2e-54 Identities = 195/673 (28%), Positives = 295/673 (43%), Gaps = 34/673 (5%) Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268 + +V LDYEQ +SY L+IRA D S S + + ++DVND P + +VSE Sbjct: 2 IYVVDELDYEQRQSYELLIRATDSVS-GVSAEVPVSVLVQDVNDCPPEIEQDSYNITVSE 60 Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTM-TDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 G +I++VQA D D G+N +TY + TD T +DP G +Y LD E Sbjct: 61 RAQFGTAILKVQAKDNDTGINQVVTYALQTDSKNTSEY---FHMDPTDGVIYLKKSLDHE 117 Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387 T + + V A+D G P S+TA F Y L+E G V Sbjct: 118 TLSHHHFTVIASDKGVPSLSSTAHVWVSVMDMNDNPPKFEQPSYTCVLSEHATRGQFVTV 177 Query: 388 LTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445 ++A+D D + +RL Y I GN + I + G+IT+ +F ++ +L VS TD Sbjct: 178 VSASDPDYIDHDRLTYTIAQGNELQTYDINPVS--GIITLVNMQNFAEKHVTILNVSVTD 235 Query: 446 SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505 G + V+I I AN + P FE+ Y V E+ G V V A D D G ++T Sbjct: 236 -GVYTSFTRVKITILPANLHNPTFEHLFYDVKVNENQLAGRLVTTVKAQDKDFGEFGRLT 294 Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTT 565 Y + IS+E + F I+ G I T K LDRE Y + + A D G + T Sbjct: 295 YFI---ISDEI----QEYFSIDKDKGEIVTKKKLDREERKLYEVPIMAMDSG--GRAGFT 345 Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625 V ++V D NDN PVF + Y A I + T+ +V A D+D N + Y + Sbjct: 346 TVRVNVGDENDNPPVFLLREYKALIQGNLTTNTTFFRVKAVDSDDNQNAVVKYSIFDSQN 405 Query: 626 E--EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS 683 + F ID +G I K+ R A DGG P + V + I I ++ Sbjct: 406 SGIKELFGIDENTGGIYLRKSAVRWENQLFQFFIRANDGGVPSLYTDVPIDIYIMSSAEN 465 Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD-DSNSFSLETRQG 742 PPVFE ++SE+S GT I ++ N Y I + + FS+ Sbjct: 466 PPVFEKKEKLLFLSESSLPGTVITRLKL-----SGNVTAKYRILSDELEEPQFSI---NN 517 Query: 743 SDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN 802 + L +D + + L +SPPL V + V D NDN P+ + F+ Sbjct: 518 VGELRLAKTLDRELKDVHLIAILAETDSSPPLTAVTDVTLHVQDENDNTPMFESNPYSFS 577 Query: 803 NYKDCFPVGPFGRVPAYDAD--VTDKLQYRILS--GNNANLILLNETTGSMTLSPQLNTN 858 ++ ++ A D+D ++Y + + G+ N+ ++ TG +T L+ Sbjct: 578 LAENIEKGSSIMKLTARDSDSGSNGDIRYSLSTEVGDIVNIFDIDAYTGWITTLVPLDKE 637 Query: 859 VPKLATMEVSVTD 871 + +V TD Sbjct: 638 KREDYKFQVIATD 650 Score = 83.0 bits (196), Expect = 1e-13 Identities = 70/236 (29%), Positives = 106/236 (44%), Gaps = 13/236 (5%) Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 LD E +++L A D S+ V V + ++D+ND PP E D +SE + GT Sbjct: 8 LDYEQRQSYELLIRATDS-VSGVSAEVPVSVLVQDVNDCPPEIEQDSYNITVSERAQFGT 66 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764 I +++A D D G N VV Y+++ DS + S + LD+E+ + Sbjct: 67 AILKVQAKDNDTGINQVVTYALQ--TDSKNTSEYFHMDPTDGVIYLKKSLDHETLSHHHF 124 Query: 765 LVIRAAS--PPLWNDVRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRV-PAY 819 VI + P L + V + V D+NDN P + + + + + G F V A Sbjct: 125 TVIASDKGVPSLSSTAHVWVSVMDMNDNPPKFEQPSYTCVLSEHATR---GQFVTVVSAS 181 Query: 820 DADVTD--KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGV 873 D D D +L Y I GN +N +G +TL N + + VSVTDGV Sbjct: 182 DPDYIDHDRLTYTIAQGNELQTYDINPVSGIITLVNMQNFAEKHVTILNVSVTDGV 237 Score = 40.7 bits (91), Expect = 0.57 Identities = 24/75 (32%), Positives = 35/75 (46%), Gaps = 10/75 (13%) Query: 1511 CQSRADCMLSICPPYSKCVTSWDSST------CTCEAGRVGPQC---VSACELGPC-GAA 1560 C+ + I P S VTS+ S+ C+C+ G G +C V+ C PC Sbjct: 1524 CEDKLVLDPKIVNPISTDVTSFVSARHVHKMECSCKEGYGGDKCQHAVNECSKSPCPNYK 1583 Query: 1561 RCVPDQTPKGYSCAC 1575 C+PD + +GY C C Sbjct: 1584 NCIPDSSDQGYHCIC 1598 >UniRef50_Q4SDW5 Cluster: Chromosome undetermined SCAF14629, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF14629, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1957 Score = 479 bits (1181), Expect = e-133 Identities = 249/691 (36%), Positives = 368/691 (53%), Gaps = 65/691 (9%) Query: 1256 LDLTGPLQIGGLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRS 1315 LDLTGPL +GG+PN+P F V N+DFVGC+ ID K ID++S++A+NGT GC K++ Sbjct: 457 LDLTGPLLLGGVPNLPEDFPVSNRDFVGCMKKLSIDSKPIDMDSHIANNGTTPGCSAKKN 516 Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLRPIQL 1375 C C+NG C W+TYICDC G+ GK+C P F G ++S++ + + Sbjct: 517 FCVKQVCHNGGVCVSKWNTYICDCPTGYGGKNCEQVMPSPQFFNGQALVSWSDPDITVAV 576 Query: 1376 PWLNALSIRTRQRDAFVMSI---------------QLKSGLLHYSYNGETMYLPMATLSD 1420 PW L RTRQ +M QL+ ++ T+ P + D Sbjct: 577 PWYMGLMFRTRQPAGTLMQANAGLSSTINLMVSEQQLRMEVMSRHQLVATLGFPQVRVDD 636 Query: 1421 GAWHR--IEIKWL--GTDI----SVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTA 1472 G WH +E++ + G DI +V++DY + + + + G + + +GGL Sbjct: 637 GEWHHLLVELRSVKEGKDIKYMAAVSLDYDMYQKSVE-IGYDLPGLKLQTLYVGGLPAAD 695 Query: 1473 GLLASDVGFFEGCIQDVRIG-TAQSLLN---RPTVRENVRDGCQSRADCMLSICPPYSKC 1528 ++ F GCIQ VR+G T+ ++ N ++ V+DGC C + CP S C Sbjct: 696 NHVSKG---FVGCIQGVRMGETSTNVANVNMAQGLKIRVKDGCDVADPCDSNTCPENSHC 752 Query: 1529 VTSWDSSTCTCEAGRV--------------------------GPQCVSACELGPCG-AAR 1561 W + TC C+ G + G +C AC+L PC + Sbjct: 753 SDDWSTHTCVCDPGNMHVHKPLSSSLKLLHITSCPLFPTGYFGKECTDACQLNPCEHVST 812 Query: 1562 CV-PDQTPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCN 1620 CV + GY+C C Y C ++ CP GWWG CGPC+CD +RG+H CN Sbjct: 813 CVRKPSSSHGYTCECGQNYY--GQYCENKVEKPCPHGWWGSPMCGPCSCDTSRGFHKDCN 870 Query: 1621 KENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANA 1680 K +G+C CK+NHY+PEG C PC+C++ GSE+ +C+A TGQC C+ GVIGR C+ C N Sbjct: 871 KTSGECRCKDNHYRPEGEDVCYPCECFSLGSESRTCDAVTGQCPCKGGVIGRQCNRCDNP 930 Query: 1681 YAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSGRATRTCDETKDVPW 1740 +AEVT ++GCEVVY+GCP++F G+WWP+T+FG T CP GS G A R C + K W Sbjct: 931 FAEVT-STGCEVVYEGCPKAFDAGIWWPKTRFGRPAATQCPKGSVGTAIRHCSDEKG--W 987 Query: 1741 QDPDMFNCTTATFYQLRKQLHKIETGELTMNTFVGVRVAADLSTACANTPRLYGADVVVA 1800 D+FNCTT TF L+K ++ M++ L +A N P +G DV A Sbjct: 988 LQADLFNCTTVTFTHLKKMNDELRRNISRMDSEHSKAAVRLLHSATTNMPHYFGNDVRTA 1047 Query: 1801 EGILLELMDYELRQAGLNLTHSQDKDYVRNLLKSTNTILNVEYEREWKRIRELTGHGAEL 1860 +L ++ YE +QAG LT +D ++ NL+++ +++L+ + W +I+ G A L Sbjct: 1048 AELLNHVLQYESQQAGFELTAMKDSEFNENLVRAGSSLLDPSNKEHWDQIQRTEGGTAHL 1107 Query: 1861 LVQKFDEYIAVLAESQHDTYTSPFEIVTKDV 1891 L + F++Y LA++ TY PF IVT ++ Sbjct: 1108 L-RNFEDYANTLAQNVRKTYLKPFTIVTDNM 1137 Score = 213 bits (520), Expect = 6e-53 Identities = 105/244 (43%), Positives = 162/244 (66%), Gaps = 16/244 (6%) Query: 867 VSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPC 926 + +TDG++ + + L V +IT++ML NSITVRL +M+ E+FLSPLL F++G+AA++ Sbjct: 14 IELTDGLHHVTVVCTLRVTIITDDMLTNSITVRLENMSQERFLSPLLSLFLEGVAAVLST 73 Query: 927 PKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTL 986 +E +++F++Q+DTDV G+ILNV+FSA +P G + L+E++YL+RT L Sbjct: 74 RREGVFLFNIQNDTDVQGSILNVTFSAMQPGGSQG----KGTFFPSEELQEQIYLNRTLL 129 Query: 987 ARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQC 1046 +++ +VLPFDDNIC+ EPC N+ +C++VLKF ++ F++S++VLFRPI+P+ C+C Sbjct: 130 RLISSQEVLPFDDNICLREPCENYMKCVSVLKFDSSPPFISSETVLFRPIHPINGLRCRC 189 Query: 1047 PEGFTGVNCETILTKASCEVD-GDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCEL 1105 P GFTG CET E+D C++ +C REGG C+ C D +T CE+ Sbjct: 190 PLGFTGDYCET-------EIDLCYSGPCKNNGRC-RSREGGYTCE-CMDD--FTGENCEV 238 Query: 1106 RARS 1109 A S Sbjct: 239 NASS 242 Score = 131 bits (317), Expect = 2e-28 Identities = 63/174 (36%), Positives = 103/174 (59%), Gaps = 16/174 (9%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 +TC+C + FTG NCE + C + G +C++G CV R GG +C+ C Y Sbjct: 223 YTCECMDDFTGENCEVNASSGRC-IPG---VCKNGGVCVNRLAGGFMCE-CP-PGEYEKP 276 Query: 1102 VCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVS 1161 CE+ RSFP SF+TF GL++R + FAT+ + LLLYNGR+N++HDF+A+E++ Sbjct: 277 YCEMTTRSFPGQSFITFRGLRQRFHFTVSFMFATRERNALLLYNGRFNQKHDFIAVEIID 336 Query: 1162 SEAGRGGGPGLRFSFSLGGGKSEIT--VEGNVGDGSWHTVEIEYFNRTITMILD 1213 + ++ +FS G ++ ++ V G V DG WH++++ Y+N+ ++D Sbjct: 337 EQ--------IQLTFSGGETRTTVSPYVPGGVSDGQWHSIQLHYYNKEGGSLVD 382 Score = 69.3 bits (162), Expect = 1e-09 Identities = 43/128 (33%), Positives = 71/128 (55%), Gaps = 14/128 (10%) Query: 2196 RTNPQCVHWS---TLRGSGEWSRVGCHTEIDYDWSPYSEEPLLINCTCNHLSTFAVLVDE 2252 RT P CV W+ + G+G WS GC + I+C CNH+++FAVL+D Sbjct: 1315 RTKPVCVFWNHSLAVGGTGGWSSKGCEL--------LNRNNSHISCQCNHMTSFAVLMDI 1366 Query: 2253 VDVEFIPEPSLLESVTSYTAFSISLPLLLTSWAALCLIRGGAATVSNSIHKHLIFSVFMA 2312 E L + +YT S+SL LLL + LCL+R + + ++IH++L+ ++F + Sbjct: 1367 SKREH--GDVLPLKIVTYTTVSVSLFLLLITLILLCLLRRLRSNL-HAIHRNLVAALFFS 1423 Query: 2313 ELLYLIAL 2320 EL++L+ + Sbjct: 1424 ELVFLLGI 1431 Score = 36.7 bits (81), Expect = 9.2 Identities = 13/39 (33%), Positives = 18/39 (46%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + C S PC N C Y C+C + TG++C Sbjct: 198 CETEIDLCYSGPCKNNGRCRSREGGYTCECMDDFTGENC 236 >UniRef50_UPI0000E473B7 Cluster: PREDICTED: similar to KIAA0279 protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to KIAA0279 protein - Strongylocentrotus purpuratus Length = 1428 Score = 475 bits (1171), Expect = e-132 Identities = 263/749 (35%), Positives = 385/749 (51%), Gaps = 52/749 (6%) Query: 1204 FNRTITMILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQ 1263 F T +ILDDCD ++L F + CA A + E RFLDL GP Sbjct: 10 FMITARIILDDCDPAVALDNGHQFD-DFTCA--------AETQFLGEL--RFLDLNGPFI 58 Query: 1264 IGGLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCY 1323 IGGLP +PS F V+N DF GC+ D YI+++ +DL + V D T GCP K + C S PC+ Sbjct: 59 IGGLPELPSEFPVENTDFDGCLRDIYINNELLDLATNVEDYNTEPGCPHKANFCESDPCH 118 Query: 1324 NGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLRPIQLPWLNALSI 1383 G C + WD Y C C G G +C ++ P RF G+ + F+ L + LPW N + Sbjct: 119 TGGSCENGWDRYHCHCSSGSGGVNCQEALSTPIRFIGESYMRFD-LTHTVSLPWTNRVVF 177 Query: 1384 RTRQRDAFVMSIQLKS----------GLLHYSYNGETMYLPMATLSDGAWHRIEIKWLGT 1433 RT Q + +M IQL + G LHY + + L T +D WH I+ +W Sbjct: 178 RTGQPNGVLMFIQLSNNINIRIELVEGHLHYVTSSVDVQLDQVTFNDREWHDIKAEWKND 237 Query: 1434 DISVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGLLASDVGFFEGCIQDVRIGT 1493 I ++ D+ + + I G+ + ++ +GG T G+ + F GC+Q + IG Sbjct: 238 KIKLSSDFD-KYKTSVRATDAINGKTVERVDLGGRLTDNGMYNA----FTGCMQGMSIG- 291 Query: 1494 AQSLLNRPTVR-ENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSAC 1552 + L+ TV N+ +GC C + CP +S CV WD++ C C G VGP CVSAC Sbjct: 292 -ERPLDPSTVEGVNIEEGCNVPRACETAKCPIHSVCVDLWDANECQCNKGYVGPDCVSAC 350 Query: 1553 ELGPC-GAARCVPDQTPK-GYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACD 1610 +L C + C D + + GY+C+C Y C E+ EC WWG CGPC CD Sbjct: 351 DLRVCEHGSSCTLDSSSEFGYTCSCSDLY--YGDHC-ENIINECADDWWGHQICGPCECD 407 Query: 1611 VTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVI 1670 G+ CNK +C+C E+ Y+P + C PC CY GS C TG C C+ G I Sbjct: 408 EEMGFESACNKTTSECYCAEHSYRPSDSDTCFPCNCYEIGSLGQDCNQETGACTCKRGAI 467 Query: 1671 GRACDACANAYAEVTPNSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSGRATR 1730 GR CD C + +AEVT GCEVVYD CP+ FA +WWPRTKFG DCP S G ATR Sbjct: 468 GRRCDECVDPHAEVTLR-GCEVVYDSCPKRFAEALWWPRTKFGKTATLDCPGESYGFATR 526 Query: 1731 TCDETKDVPWQDPDMFNCTTATFYQLRKQLHKIETGELTMNTFVGVRVAADLSTACANTP 1790 CD + WQ P +FNCT+ F +L+ L ++ G+ + V +A L A T Sbjct: 527 YCD--IETNWQTPSLFNCTSDNFLRLQNILQTLQNGQ-KLYPEVSFNIAMQLQEATNETD 583 Query: 1791 RLYGADVVVAEGILLELMDYELRQAGLNLTHSQDKDYVRNLLKSTNTILNVEYEREWKRI 1850 +G D+ +A +L L+ +E +Q GLN+T + K + +N++++ + + + W+ I Sbjct: 584 LFHGNDINIAYQVLGYLLRHESKQVGLNVTATIMKSFTKNIVETVSRLFEPQNRIHWEMI 643 Query: 1851 RELTGHGAELL--VQKFDEYIAVLAESQHDTYTSPFEIVTKDVVISVDTVTSESIYGFEP 1908 ++ + AE++ ++KF IA S +YT F I+T ++++ D + ++ Sbjct: 644 QQTSRGTAEIMEDMEKFALNIAKFTNS--FSYTPEFSIITPNIIMHHDIILRDN------ 695 Query: 1909 TQLNRLNVDSYTTERVVALPDTSAFIHSP 1937 + V Y E +++L D S +H P Sbjct: 696 --FSMRAVPEYEMETLLSLEDNSQ-VHIP 721 Score = 67.3 bits (157), Expect = 6e-09 Identities = 44/165 (26%), Positives = 77/165 (46%), Gaps = 11/165 (6%) Query: 2163 VGKKMYRSLSGIRLKKPIRLQIWLDINRETFGSRTNPQCVHWSTL--RGSGEWSRVGCHT 2220 V +Y L+ L P+ + ++ +R+ PQCV+W G+G WS GC Sbjct: 782 VSFSIYDELANGTLPDPLLTPVIVEFQSIDAVNRSGPQCVYWDFEFNNGTGGWSTYGC-- 839 Query: 2221 EIDYDWSPYSEEPLLINCTCNHLSTFAVLVDEVDVEFIPEPSLLESVTSYTAFSISLPLL 2280 + S Y+ INC+C+HL+ AV++D ++ E + S+ Y I++ L Sbjct: 840 ----ELSGYNRTH--INCSCSHLTNIAVIMDNAPYMYVEEVMITLSIAVYIGVGIAILCL 893 Query: 2281 LTSWAALCLIRGGAATVSNSIHKHLIFSVFMAELLYLIALKARTS 2325 L ++ L + T NSIH +L F + AE+ + + + + Sbjct: 894 LITFLTLLGV-SNLHTNLNSIHINLCFVLIAAEVTFGVGISTENN 937 >UniRef50_Q8MY78 Cluster: Ap-cadherin; n=1; Patiria pectinifera|Rep: Ap-cadherin - Asterina pectinifera (Starfish) Length = 2909 Score = 472 bits (1164), Expect = e-131 Identities = 451/1653 (27%), Positives = 703/1653 (42%), Gaps = 175/1653 (10%) Query: 9 QQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAE-VEYTIELVTA 67 Q++NV D ND +P F + + + E + V ++A D D + + Y+++ + Sbjct: 1150 QRVNVQDVNDETPQFPVTNFFVAFPEDVDAPFLVTRVQAEDADTETAFKTITYSLDQTFS 1209 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 D FRID +G L + DRE Y+V V ATD A Sbjct: 1210 DA------------------QYFRIDPTTGDLTSTIKFDRESEDSYSVQVIATDGAPSSL 1251 Query: 128 DRLSST----ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183 + +N++D NDN P F YT ++ ED V + ++ ATD D Sbjct: 1252 PSAGGPNKGYLRVVINVVDKNDNPPVFDRPMYTRTIREDEPVGYE--VIQVTATDVD--P 1307 Query: 184 NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 +S RY I NT F +D +G +S+ LDYE R Y L+ A DG + + +T + Sbjct: 1308 DSIPRYLITANNTGGAFEVDPATGAISIASPLDYETQREYWLMYSANDGLNVA---STVI 1364 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVP-IGYSIVRVQAYDAD-EGVNAELTYTMTDKDY 301 I + +VND P F ++ VSEN P + +++V A D D + V A++ Y++ + Sbjct: 1365 RIQLENVNDEKPEFELPVYTAEVSENDPNVPRQLLQVTAVDGDADAVQADIRYSL---EG 1421 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 TG TID +G + + LDRE+ + ++LLV ATDGG S T Sbjct: 1422 TG-AGTTFTIDAVTGQITLTEMLDRESVSIWKLLVKATDGGGTGTSLTGYADLEVTVLDE 1480 Query: 362 XXXX-FMPG-QYEVELAEDEPPGTPVVTLTATDADEDN---RLHYEITGGNT-----RGR 411 F P +Y + E+ P GTPV+ +TA D D+ N R+ Y + G Sbjct: 1481 NDNSPFFPELEYRGSVPENSPGGTPVMQVTAIDYDDPNQFGRITYSTISSSEIPNDGSGL 1540 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN 471 F I G + LD ++ Y L + A+D I I D N+ APVF Sbjct: 1541 FQIDGSTGWVTVKSGAVLDREKNDTYTLRIRASDVPNSEALTDAIIQILDVNDNAPVFVG 1600 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT- 530 PY SV E P+G TV VS TD+DV N ++ + + N + + V +P T Sbjct: 1601 GPYATSVEETQPVGATVWEVSVTDADVDFNEEVQFGIIG--GNVGGSF---EIVADPLTL 1655 Query: 531 -GAITTNKLLDRETMSG-YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY-T 587 G I + LD E+ + Y LT+T D P T + I V+DVND P F Y + Sbjct: 1656 IGIIRIARPLDYESPNKLYTLTITVDDNSGPGSQSQTTITIDVLDVNDVAPTFNPAEYVS 1715 Query: 588 ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV-------IR 640 AN++E VGTS+ V A+D + G+ G+ + +DP +G F I+ S + ++ Sbjct: 1716 ANVLESVDVGTSIGTVSASDPEAGVFGQFTFSIDPASDPDGLFSIEEISPIGAVRRADVK 1775 Query: 641 TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700 T K LDRE+V TH L A D G PP + +++ ++D+ND+PP F +D I EN Sbjct: 1776 TAKPLDRENVETHVLTLRATDLGVPPLTGYATLNLTLDDVNDTPPTFATDYRP-TIKENL 1834 Query: 701 PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS---LETRQGSDKAELVTMVDLDYE 757 +G I A D D ++ D++SF+ + G++ + + D E Sbjct: 1835 AEVQFVGYISAKDEDPTGGPPFTLVVEPNTDTDSFTWFDVGGTTGNNLSISSKAISFDRE 1894 Query: 758 SPRKKYELVIRAASPPLWNDVRVEILVTDV---NDNAPVMKDFQIIFNNYKDCFPVGPFG 814 + + Y + IR + V L+ ++ NDN +++ +++ P P G Sbjct: 1895 T-QATYSIPIRITDRAPNGNSGVNYLIVEIEDENDNPHFGTTKEMLVYSFEGNIPDSPIG 1953 Query: 815 RVPAYDAD-VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-G 872 V D D + DK Y LS ++E TG +T+ L +V V+D G Sbjct: 1954 YVGVDDKDTLEDKTYYPELSDVYKQYFRVDEDTGQVTI---LAGTPAGTYEFDVRVSDGG 2010 Query: 873 VN-EIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLG------FFIDG-LAAII 924 V+ + + + + VR I EE + +S + R +TAE+ +S G + G LA II Sbjct: 2011 VHADQTSTVIVDVRDIPEEAVRSSGSFRFEGVTAEELISVPSGGGQTKLDILKGILAEII 2070 Query: 925 PCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRT 984 P EN+ IFSV +NV D G SP+Y P + +R Sbjct: 2071 PAKPENVDIFSV----------INVPNQPTTVDVRYSAHG--SPYYPPEQMDGAALANRD 2118 Query: 985 TLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTC 1044 +A+ V + ++C+ E C VL+ +N+ S F + T C Sbjct: 2119 RIAQALGVTIGMIKIDMCLLESACE-SACTNVLEIDPQPTVINTPSASFTAVTTSTVAKC 2177 Query: 1045 QCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCE 1104 C G N + C+ D C +G C + GG CQ C Y C+ Sbjct: 2178 VC-----GANTQ---QPGLCDFDA----CLNGGTCTETQGGGHTCQ-C--PTGYDGPDCQ 2222 Query: 1105 LRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRY-----NERHDFLALEL 1159 R F F F L++ H L+F T G+LLYNG + DF+ ++L Sbjct: 2223 QTTREFK-DGFAHFGTLQQCEETHTSLEFITTAAEGVLLYNGPMIPVTGDMPEDFMLIQL 2281 Query: 1160 VSSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKVL 1219 + GG P L + G + N+GDG WH +++ + + +LD C Sbjct: 2282 L------GGQPVLEINLGSGTLSLSLPATTNLGDGKWHRLDVYRNGKDVEFMLDRC---- 2331 Query: 1220 SLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNK 1279 D + A + +R+ + ++FL++ PLQ+GG+ Sbjct: 2332 -----KDAAVAEASTSSSRQTDQCKITGQAPGDNKFLNVNTPLQLGGIDKSAGFTYPDGI 2386 Query: 1280 DFV----GCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTY 1335 F GC+ + D DL + G+ AGC S+ C NG C + TY Sbjct: 2387 TFAASYDGCMKNLEQDSTLYDLETPGKAVGSEAGC----SKLVCGECNNGT-CEGDFSTY 2441 Query: 1336 ICDCKEGHTGKDCADSTGPPWRFGGDGMLSF--NPLLRPIQLPWLNALSIRTRQRDAFVM 1393 C C G+TG+ C D T P + F + + + P + +S RTR+ + + Sbjct: 2442 TCLCDPGYTGEKC-DQTTPAYDFATESYVRYQLKPTIVIDSREGNYQVSFRTREDEGLLW 2500 Query: 1394 SI-----------QLKSGLLHYSYN---GE-TMYLPMATLSDGAWHRIEIKWLGTDISVT 1438 +I +L +G + +N GE +MYL ++DG WH + ++ I+V Sbjct: 2501 TITNLNGLEFTTLELINGYIRSRWNLGDGEHSMYLDQYAVNDGDWHMVHLERFDFYITVR 2560 Query: 1439 VDYGLRTVLMPMLANKIQGQYI--GKILIGGLDTTAGLLASDVGFFEGCIQDVRIGT--- 1493 +D G M + + +L+G ++ D F+GC+ D RI Sbjct: 2561 IDGGGGVRQMESRESTFSTLEVDPNSLLLGAFVVHVVDISQD---FQGCMNDPRINNYYL 2617 Query: 1494 ---AQSLLNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAG--RVGPQC 1548 +S P +V +GC S C + CP C W C C+ G +G C Sbjct: 2618 GFETESDYAIPQPTASVTEGCPSYDPCASNPCPVPFICKDVWRKYICICKPGFEELGNTC 2677 Query: 1549 VSA--CELGPCGAARCVPDQTPKGYSCACEPGY 1579 V+ C+ PC D+ G+ C C GY Sbjct: 2678 VAIDDCDPNPCLNGGICTDR-DSGFECECPDGY 2709 Score = 205 bits (501), Expect = 1e-50 Identities = 235/887 (26%), Positives = 371/887 (41%), Gaps = 78/887 (8%) Query: 7 IHQQINVLDCNDHSPVFEMQQYE-ASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELV 65 + + V D ND P FE + Y +V E + T + T+ ATD D N + Y+ L+ Sbjct: 631 VRVNVEVTDINDCVPKFERETYSFRNVIETIDTTTPIGTVAATDCDADPNNILTYS--LI 688 Query: 66 TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKV-ARYTVLVKATDQAS 124 A D FR+D + G L LD + Y + + DQA Sbjct: 689 GAQA------------------DKFRLDSQ-GVLYAATELDYDVGDGSYELEAQVRDQAG 729 Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS-VDEDISVTDNPVIAKIKATDADVGA 183 + TAT+ V + D ND P F +V +DED + +I + A+DAD Sbjct: 730 G-----ADTATVWVYLTDVNDEGPVFLNTDGSVYYIDEDAPL--GYIIGTVYASDAD--K 780 Query: 184 NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 I + I G +T F ID +G +S + T + + SYR + A DG ++ ++ Sbjct: 781 TDTITFGIQGSST---FQIDPQTGVISRIGTGNLPEA-SYRFNVTATDG---KYTSDAEV 833 Query: 244 LINIRDVNDNAPRFYT-SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 I + D+NDN P F + + S+SE+ IG +++VQA DAD+GVNAE+ Y D Sbjct: 834 EIQVNDINDNTPIFPDCNSYAPSISESAAIGTFLIKVQATDADKGVNAEIAY-----DIA 888 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD--GGDPPRSATATXXXXXXXXX 360 G+ + P TID +G + T LDRET ++VTA D G Sbjct: 889 GS-NNPFTIDAVTGDISTQDPLDRETTPTIDIVVTAQDNPGSIFSNQGFCIITVNITDVN 947 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420 F Y V ++ P P++ + DAD + T G T + N Sbjct: 948 DNRPTFPLEDYVVIISNTAPQFAPILKVEVEDADLPTPAGF--TYGLTTQNPVLFEINQN 1005 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDAN-NYAPVFENAPYTASVF 479 G I L + + V A D R+ + VQ+ + + P + + +V Sbjct: 1006 GEIFPVADLSVYDDNTFNFKVEAEDGPNRA-KSNVQVKVLATGVDQPPEWVSTFPDITVM 1064 Query: 480 EDAPIGTTVLVVSA-TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 E+ I + + A + S G+ ++ + ++E Q V + + + Sbjct: 1065 ENISINDVIGTLQAQSRSGNGVGYRVVQGQIPQTNSE--GQFAVQNVGDSMIANLYISAP 1122 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 LD ET Y L V A D G LS ++V DVND P F + ED Sbjct: 1123 LDYETTKFYTLQVEAYDDG-NRLSILGTQRVNVQDVNDETPQFPVTNFFVAFPEDVDAPF 1181 Query: 599 SVSQVGATDADVGLNGR-IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 V++V A DAD + I Y LD + F IDP +G + + DRES ++ ++ Sbjct: 1182 LVTRVQAEDADTETAFKTITYSLDQTFSDAQYFRIDPTTGDLTSTIKFDRESEDSYSVQV 1241 Query: 658 VAIDGGTP-------PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710 +A DG P + V I + D ND+PPVF+ T I E+ P+G + ++ Sbjct: 1242 IATDGAPSSLPSAGGPNKGYLRVVINVVDKNDNPPVFDRPMYTRTIREDEPVGYEVIQVT 1301 Query: 711 AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770 A D D P+++ Y I + +F ++ G+ + LDYE+ R +Y L+ A Sbjct: 1302 ATDVD--PDSIPRYLITANNTGGAFEVDPATGA----ISIASPLDYETQR-EYWLMYSAN 1354 Query: 771 SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP--FGRVPAYDAD---VTD 825 + I + +VND P + + + P P +V A D D V Sbjct: 1355 DGLNVASTVIRIQLENVNDEKPEF-ELPVYTAEVSENDPNVPRQLLQVTAVDGDADAVQA 1413 Query: 826 KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 ++Y + ++ TG +TL+ L+ + + V TDG Sbjct: 1414 DIRYSLEGTGAGTTFTIDAVTGQITLTEMLDRESVSIWKLLVKATDG 1460 Score = 187 bits (455), Expect = 4e-45 Identities = 220/808 (27%), Positives = 346/808 (42%), Gaps = 72/808 (8%) Query: 89 VFRIDGRSGALLTRASLDR--EKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146 +F +D SG + T S + ++ +Y + V A D+ S+ VNI + + Sbjct: 487 LFTVDEESGWIKTSLSEGQGYQQGQKYILSVYAQDENG-------SSIPAEVNIFGGS-H 538 Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQM---QFSID 203 PQF+++ Y V+V E++ N + DA +N A+ +A++ T + SID Sbjct: 539 PPQFTQEVYNVAVTEEVIGEQNVI-----DIDAFSFSNVAVTFALLNSETNQPIPRHSID 593 Query: 204 SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263 SG + L++ +D E + SY L ++A + S T ++ + + D+ND P+F + Sbjct: 594 PSSGQIKLLEKVDREVLDSYFLEVQATEDVQDGLSTTVRVNVEVTDINDCVPKFERETYS 653 Query: 264 -ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322 +V E + I V A D D N LTY++ G +D + G +Y + Sbjct: 654 FRNVIETIDTTTPIGTVAATDCDADPNNILTYSL-----IGAQADKFRLDSQ-GVLYAAT 707 Query: 323 QLDRET-QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ-YEVELAEDEP 380 +LD + Y+L D +AT G Y ++ ED P Sbjct: 708 ELDYDVGDGSYELEAQVRDQAGGADTATVWVYLTDVNDEGPVFLNTDGSVYYID--EDAP 765 Query: 381 PGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440 G + T+ A+DAD+ + + + I G +T F I Q G + E Y Sbjct: 766 LGYIIGTVYASDADKTDTITFGIQGSST---FQIDPQTG---VISRIGTGNLPEASYRFN 819 Query: 441 VSATDSGGRSDTAMVQINITDANNYAPVFENA-PYTASVFEDAPIGTTVLVVSATDSDVG 499 V+ATD SD A V+I + D N+ P+F + Y S+ E A IGT ++ V ATD+D G Sbjct: 820 VTATDGKYTSD-AEVEIQVNDINDNTPIFPDCNSYAPSISESAAIGTFLIKVQATDADKG 878 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD--GG 557 +NA+I Y +A + F I+ TG I+T LDRET + VTA+D G Sbjct: 879 VNAEIAYD---------IAGSNNPFTIDAVTGDISTQDPLDRETTPTIDIVVTAQDNPGS 929 Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617 + S + +++ DVNDN P F + Y I A + +V DAD+ Sbjct: 930 IFSNQGFCIITVNITDVNDNRPTFPLEDYVVIISNTAPQFAPILKVEVEDADLPTPAGFT 989 Query: 618 YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 Y L ++ F I+ +G I L T + K A DG +S+ V V + Sbjct: 990 YGLTTQN--PVLFEIN-QNGEIFPVADLSVYDDNTFNFKVEAEDGPNRAKSN-VQVKVLA 1045 Query: 678 EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD-PDEGPN-AVVHYSIKGGDDSNSF 735 + D PP + S + EN I IG ++A G VV I + F Sbjct: 1046 TGV-DQPPEWVSTFPDITVMENISINDVIGTLQAQSRSGNGVGYRVVQGQIPQTNSEGQF 1104 Query: 736 SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDV--RVEILVTDVNDNAPV 793 +++ S A L LDYE+ K Y L + A + + V DVND P Sbjct: 1105 AVQNVGDSMIANLYISAPLDYET-TKFYTLQVEAYDDGNRLSILGTQRVNVQDVNDETP- 1162 Query: 794 MKDFQIIFNNYKDCFPV---GPF--GRVPAYDADVT---DKLQYRI-LSGNNANLILLNE 844 Q N+ FP PF RV A DAD + Y + + ++A ++ Sbjct: 1163 ----QFPVTNFFVAFPEDVDAPFLVTRVQAEDADTETAFKTITYSLDQTFSDAQYFRIDP 1218 Query: 845 TTGSMTLSPQLNTNVPKLATMEVSVTDG 872 TTG +T + + + +++V TDG Sbjct: 1219 TTGDLTSTIKFDRESEDSYSVQVIATDG 1246 Score = 177 bits (431), Expect = 4e-42 Identities = 230/904 (25%), Positives = 397/904 (43%), Gaps = 119/904 (13%) Query: 19 HSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXX 78 H PVF + S+ E + GT T+ ATD+D+G+N V Y + Sbjct: 221 HPPVFAFSSFIYSIAENSPVGTIAGTVFATDEDMGENGRVTYHL---------------- 264 Query: 79 XXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHV 138 + F + SG + + V YT+ V A D +P + S+ + + Sbjct: 265 -----LKLNRYFTVGQESGLVTVT---EPTPVGEYTMQVVARDAGTPFQE--SAPVPLQI 314 Query: 139 NIIDDNDNY----------PQFS-EKTYTVSV--DEDISVTDNPVIAKIKATDADVGANS 185 ++I + N P + K + V +E + V ++ I + T + + N Sbjct: 315 SVISSSSNMIPYGNDMMFAPDYKPSKRFRREVLPEERVPVNEDTAINTVIFTVSSL--ND 372 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 R+A +G + F ++ +G+V L+ L++EQ + + + + + +T +++I Sbjct: 373 TDRFAYVGTPNPL-FGLNETTGEVKLLDQLNFEQATVHEFEVEITNVENTDKRDTQRIII 431 Query: 246 NIRDVNDNAPRFYTSLFQ--ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 +++VN+ P++ ++ E V + P G SI ++A D + +++ + + +G Sbjct: 432 EVQNVNE-PPQWEIGVYPYIEVVPVDAPTGASIFHLRASDPE---GSDVRFYLN----SG 483 Query: 304 NVDLPITIDPRSGWVYTS---GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 L T+D SGW+ TS GQ ++ Q KY L V A D + ++ Sbjct: 484 GSGL-FTVDEESGWIKTSLSEGQGYQQGQ-KYILSVYAQD-----ENGSSIPAEVNIFGG 536 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTR---GRFSITSQ 417 F Y V + E+ V+ + A + + + + + T R SI Sbjct: 537 SHPPQFTQEVYNVAVTEEVIGEQNVIDIDAF-SFSNVAVTFALLNSETNQPIPRHSIDPS 595 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATD--SGGRSDTAMVQINITDANNYAPVFENAPYT 475 +G+ I + + +D + Y L V AT+ G S T V + +TD N+ P FE Y+ Sbjct: 596 SGQ--IKLLEKVDREVLDSYFLEVQATEDVQDGLSTTVRVNVEVTDINDCVPKFERETYS 653 Query: 476 -ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 +V E T + V+ATD D N +TYSL + +F ++ Q G + Sbjct: 654 FRNVIETIDTTTPIGTVAATDCDADPNNILTYSL--------IGAQADKFRLDSQ-GVLY 704 Query: 535 TNKLLDRETMSG-YLLTVTARD--GGVPSLSDTTDVEISVVDVNDNEPVF-KQQLYTANI 590 LD + G Y L RD GG +DT V + + DVND PVF I Sbjct: 705 AATELDYDVGDGSYELEAQVRDQAGG----ADTATVWVYLTDVNDEGPVFLNTDGSVYYI 760 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650 EDA +G + V A+DAD I + + + +F IDP +GVI + Sbjct: 761 DEDAPLGYIIGTVYASDAD--KTDTITFGI----QGSSTFQIDPQTGVI-SRIGTGNLPE 813 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF--YISENSPIGTTIGE 708 A++ A DG +S V I++ DIND+ P+F DC ++ ISE++ IGT + + Sbjct: 814 ASYRFNVTATDG---KYTSDAEVEIQVNDINDNTPIF-PDCNSYAPSISESAAIGTFLIK 869 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768 ++A D D+G NA + Y I G +N F+++ G ++ T LD E+ ++V+ Sbjct: 870 VQATDADKGVNAEIAYDIAG--SNNPFTIDAVTG----DISTQDPLDRET-TPTIDIVVT 922 Query: 769 AASPP--LWND---VRVEILVTDVNDNAPV--MKDFQIIFNNYKDCFPVGPFGRVPAYDA 821 A P ++++ + + +TDVNDN P ++D+ +I +N F P +V DA Sbjct: 923 AQDNPGSIFSNQGFCIITVNITDVNDNRPTFPLEDYVVIISNTAPQF--APILKVEVEDA 980 Query: 822 DVTDKLQYRI-LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMM 880 D+ + L+ N L +N+ G + L+ +V DG N K+ + Sbjct: 981 DLPTPAGFTYGLTTQNPVLFEINQ-NGEIFPVADLSVYDDNTFNFKVEAEDGPNRAKSNV 1039 Query: 881 QLSV 884 Q+ V Sbjct: 1040 QVKV 1043 Score = 77.8 bits (183), Expect = 4e-12 Identities = 88/403 (21%), Positives = 170/403 (42%), Gaps = 40/403 (9%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDA-----DEDNRLHYEITG-GNTRGRFSITSQNG 419 F +Y+ ++E+ P G V L+ + + YE+ G G+ ++ + Sbjct: 119 FADSRYQGVISENSPLGEKVRGLSDLRVVVPIYAQGMPVQYELLGQGSDNFHLEVSEDDS 178 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479 + PL ++ Y LT+ A + + AM ++ I + PVF + + S+ Sbjct: 179 TVGVYADAPLQVAEKEFYKLTLEAVVN---DEVAMTEVQIWVLGLHPPVFAFSSFIYSIA 235 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E++P+GT V ATD D+G N ++TY L ++ F + ++G +T + Sbjct: 236 ENSPVGTIAGTVFATDEDMGENGRVTYHL---------LKLNRYFTVGQESGLVT---VT 283 Query: 540 DRETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNE-PVFKQQLYTANIMEDALVG 597 + + Y + V ARD G P S ++ISV+ + N P ++ + Sbjct: 284 EPTPVGEYTMQVVARDAGTPFQESAPVPLQISVISSSSNMIPYGNDMMFAPDYKPSKRFR 343 Query: 598 TSV--SQVGATDADVGLNGRIHYELDPKDREEGSFV--------IDPASGVIRTNKALDR 647 V + + D +N I D + ++V ++ +G ++ L+ Sbjct: 344 REVLPEERVPVNEDTAINTVIFTVSSLNDTDRFAYVGTPNPLFGLNETTGEVKLLDQLNF 403 Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF--YISENSPIGTT 705 E H+ + + + T + I+++++N+ PP +E + + ++P G + Sbjct: 404 EQATVHEFEVEITNVENTDKRDTQRIIIEVQNVNE-PPQWEIGVYPYIEVVPVDAPTGAS 462 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAEL 748 I +RA DP EG + V Y GG S F+++ G K L Sbjct: 463 IFHLRASDP-EGSD-VRFYLNSGG--SGLFTVDEESGWIKTSL 501 Score = 64.9 bits (151), Expect = 3e-08 Identities = 148/642 (23%), Positives = 248/642 (38%), Gaps = 59/642 (9%) Query: 245 INIRDVN---DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE---LTYTMTD 298 IN+R VN D+ F S +Q +SEN P+G + + + A+ + Y + Sbjct: 104 INVRIVNTGRDSKLHFADSRYQGVISENSPLGEKVRGLSDLRVVVPIYAQGMPVQYELLG 163 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358 + + N L ++ D + VY L + Y+L + A + A Sbjct: 164 QG-SDNFHLEVSEDDSTVGVYADAPLQVAEKEFYKLTLEAVVNDE-----VAMTEVQIWV 217 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITS 416 F + +AE+ P GT T+ ATD D E+ R+ Y + N R+ Sbjct: 218 LGLHPPVFAFSSFIYSIAENSPVGTIAGTVFATDEDMGENGRVTYHLLKLN---RYFTVG 274 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQIN-ITDANNYAPVFENA 472 Q GL+TV +P + Y + V A D+G S +QI+ I+ ++N P + Sbjct: 275 QES-GLVTVTEPTPVGE---YTMQVVARDAGTPFQESAPVPLQISVISSSSNMIPYGNDM 330 Query: 473 PYTASVFEDAPIGTTVLVVS--ATDSDVGINAQI-TYSLSSEISNEA-VAHHDQQFVINP 528 + VL + D IN I T S ++ A V + F +N Sbjct: 331 MFAPDYKPSKRFRREVLPEERVPVNEDTAINTVIFTVSSLNDTDRFAYVGTPNPLFGLNE 390 Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL--Y 586 TG + L+ E + + V + DT + I V +VN+ P ++ + Y Sbjct: 391 TTGEVKLLDQLNFEQATVHEFEVEITNVENTDKRDTQRIIIEVQNVNE-PPQWEIGVYPY 449 Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646 + DA G S+ + A+D + G + R + G F +D SG I+T +L Sbjct: 450 IEVVPVDAPTGASIFHLRASDPE-GSDVRFYL----NSGGSGLFTVDEESGWIKT--SLS 502 Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706 K + S++ + I PP F + ++E I Sbjct: 503 EGQGYQQGQKYILSVYAQDENGSSIPAEVNIFG-GSHPPQFTQEVYNVAVTEE-----VI 556 Query: 707 GEIRAHDPD--EGPNAVVHYSIKGGDDSNSFSLET-RQGSDKAELVTMVDLDYESPRKKY 763 GE D D N V +++ + + + S + +L+ VD + Y Sbjct: 557 GEQNVIDIDAFSFSNVAVTFALLNSETNQPIPRHSIDPSSGQIKLLEKVDREV---LDSY 613 Query: 764 ELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCF-PVGPFGRVPA- 818 L ++A L VRV + VTD+ND P + F N + P G V A Sbjct: 614 FLEVQATEDVQDGLSTTVRVNVEVTDINDCVPKFERETYSFRNVIETIDTTTPIGTVAAT 673 Query: 819 -YDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNV 859 DAD + L Y ++ G A+ L ++ G + + +L+ +V Sbjct: 674 DCDADPNNILTYSLI-GAQADKFRL-DSQGVLYAATELDYDV 713 >UniRef50_A7RQM0 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1852 Score = 471 bits (1161), Expect = e-130 Identities = 315/895 (35%), Positives = 465/895 (51%), Gaps = 62/895 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ V D ND+ P F Y +V E ++G V + ATD D G N ++ Y+I Sbjct: 672 KVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSI------- 724 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L+ + F +D +G + TR LDRE +A Y++ + A D S V R Sbjct: 725 LSGNENMA------------FAMDRFTGEITTRVPLDRETIASYSLTINA-DDGSLV--R 769 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + T++++I D+NDN P F+ + ++ ED S T V ++ ATD D+G N A+ Y Sbjct: 770 FMAATTVNISIADENDNQPTFTGPS-RFNISED-SPTGTRV-GQLTATDRDIGPNGAVTY 826 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 AII GN F +D SG +S+ TLD E + SY LV++A D GSP +S T + +++ D Sbjct: 827 AIISGNQGNSFQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSPQQSITASIHVSVLD 886 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 VNDNAPRF SLF + E+ + ++++V+ D DEG N +T ++ +G Sbjct: 887 VNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITLSL-----SGEGSDNF 941 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 TID +G+V + LD ET A YQL VTA DGG P +SATA F+ Sbjct: 942 TID-STGFVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSP 1000 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 + ED T VV L ATD+D L ++I GN F I + GLI+VA+ L Sbjct: 1001 AQVTSIPEDVAINTHVVKLNATDSD-GTPLTFDIVEGNAGSSFKIDQSS--GLISVAKRL 1057 Query: 430 DFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 D + Y L V AT++G + ++ I + D N+ APVF Y S+ E+ PIG T Sbjct: 1058 DRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQT 1117 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 V V+ATD D G NA++TY LS +F +NP TG +TT + LDRE + Y Sbjct: 1118 VAKVTATDRDEGENAKVTYELS--------VGDTSKFEVNPATGLVTTKRPLDREDQASY 1169 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 L VTA D G PS S + +++ D+NDN P F Q YT + E+ G+++ +V A+D Sbjct: 1170 SLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASD 1229 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 D G NGR+ Y + +F ID +G I +DRE++A+++L A D G PP Sbjct: 1230 PDAGANGRVTYSI-ISGNHGNAFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPPW 1288 Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 ST V I + D ND+ P+F S+ ++ I E IG+ + + A D DEG NA V YSI Sbjct: 1289 VSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIV 1348 Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILV 784 GD S +F++ G L +++ E+ Y L IRA+ SP + +D + ++V Sbjct: 1349 RGDTS-AFAINAMNG----VLTVKKEINRETV-PTYTLTIRASDRGSPMMTSDKELTVVV 1402 Query: 785 TDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILL 842 DVNDN PV I + ++ V A D+DV L+Y I+SGN+ + Sbjct: 1403 NDVNDNPPVFNSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGNDEKRFKI 1462 Query: 843 NETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSIT 897 N T+G + + L+ +EV+ TD ++ A +++R+I LN IT Sbjct: 1463 NSTSGVIMTTTPLDFEEKSQYGLEVTATD--SKYTAKTNVTIRVIN----LNDIT 1511 Score = 447 bits (1102), Expect = e-123 Identities = 291/789 (36%), Positives = 405/789 (51%), Gaps = 59/789 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND++P F + Y+ V E + G+ V L A D D+G NA + Y+ LV+ DT Sbjct: 156 ITVDDVNDNAPFFALSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYS--LVSGDT- 212 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F +D + G + T+ + DRE A Y V ++A D SP Sbjct: 213 -----------------SYFTVDSQ-GVIRTKGAFDRETKASYQVALRAQDGGSPSR--- 251 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S AT+ + I+D NDN P FS YT SVDED+++ + + A+D D G N+ +RY+ Sbjct: 252 SGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAI--GAAMVTVTASDKDNGNNADLRYS 309 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 GNT F++D+++G V++ ++LD+EQ SY L + D GSP ++T+ LLIN+ D+ Sbjct: 310 FTSGNTNHAFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDI 369 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F S +Q V EN P G +V A D D N L + + GN D T Sbjct: 370 NDNPPVFSPSAYQSRVKENTPAG---TQVSATDRDSSTNGALVFGIIK----GNDDGVFT 422 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 ID +G + + D E + +Y L V A D G P + TA F P Sbjct: 423 IDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSN 482 Query: 371 YEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 Y ++ E G+ VVT+TATD D RL Y + GN +G F+I + +G I V+ Sbjct: 483 YSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRLISGNVKGAFNIDANSGS--IRVSSE 540 Query: 429 LDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD + Y L V A D G RS + V I + D N+ +P+F+ PY V E + G Sbjct: 541 LDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQG-PYVFRVSESSSPGH 599 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 + V+ATD+D N + Y+LS + F IN TG IT LD E + Sbjct: 600 QIGQVAATDADDSSNGDVRYALSD---------NTDVFSINTSTGLITLKTQLDYEKKTQ 650 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y++TVTA+DGG PS S T V++ V DVNDN P F + LYT + E+ G +V V AT Sbjct: 651 YMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTAT 710 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 DAD G NG+I Y + E +F +D +G I T LDRE++A++ L A DG Sbjct: 711 DADSGANGKISYSI-LSGNENMAFAMDRFTGEITTRVPLDRETIASYSLTINADDGSLVR 769 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 + V+I I D ND+ P F F ISE+SP GT +G++ A D D GPN V Y+I Sbjct: 770 FMAATTVNISIADENDNQPTFTGPS-RFNISEDSPTGTRVGQLTATDRDIGPNGAVTYAI 828 Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEIL 783 G+ NSF L+ R G L LD E+ Y LV++A+ SP + + Sbjct: 829 ISGNQGNSFQLDPRSGI----LSVRSTLDRET-IPSYTLVVKASDAGSPQQSITASIHVS 883 Query: 784 VTDVNDNAP 792 V DVNDNAP Sbjct: 884 VLDVNDNAP 892 Score = 446 bits (1099), Expect = e-123 Identities = 292/884 (33%), Positives = 457/884 (51%), Gaps = 56/884 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I++ D ND+ P F ++ E + +GT V L ATD+DIG N V Y I ++ + Sbjct: 778 ISIADENDNQPTFTGPS-RFNISEDSPTGTRVGQLTATDRDIGPNGAVTYAI--ISGNQG 834 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N F++D RSG L R++LDRE + YT++VKA+D SP + Sbjct: 835 NS-----------------FQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSP---QQ 874 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S TA+IHV+++D NDN P+F + ++ + ED SV + + ++K D D G+N AI + Sbjct: 875 SITASIHVSVLDVNDNAPRFEKSLFSGEIREDASV--HSTVLQVKVEDKDEGSNGAITLS 932 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + G + F+IDS +G V LDYE +Y+L + A+DGGSPS+S T Q+ I I +V Sbjct: 933 LSGEGSD-NFTIDS-TGFVLSKTPLDYETTAAYQLTVTARDGGSPSKSATAQVKITIINV 990 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F + S+ E+V I +V++ A D+D LT+ + + GN Sbjct: 991 NDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDSD---GTPLTFDIVE----GNAGSSFK 1043 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 ID SG + + +LDRET A Y L+V AT+ G S F PG Sbjct: 1044 IDQSSGLISVAKRLDRETTANYTLVVRATETGSQGESVYNNATIRVLDVNDNAPVFNPGS 1103 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 Y L E+ P G V +TATD DE ++ YE++ G+T +F + G L+T +P Sbjct: 1104 YAKSLHENLPIGQTVAKVTATDRDEGENAKVTYELSVGDT-SKFEVNPATG--LVTTKRP 1160 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGT 486 LD + + Y L V+A D G S +A+ I +T D N+ +P F + YT +V E+ G+ Sbjct: 1161 LDREDQASYSLRVTAMDHGKPSQSAVAAITLTINDLNDNSPQFSQSKYTLTVTENTANGS 1220 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 +L V A+D D G N ++TYS+ S +H F I+ TG IT ++DRE ++ Sbjct: 1221 NILRVLASDPDAGANGRVTYSIIS-------GNHGNAFRIDSTTGRITVVGVVDREALAS 1273 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y LT++A+D GVP T V I+V D NDN P+F + I E +G+ V+ V AT Sbjct: 1274 YNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSRVAVVTAT 1333 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D D G N ++ Y + D +F I+ +GV+ K ++RE+V T+ L A D G+P Sbjct: 1334 DRDEGSNAQVFYSIVRGDTS--AFAINAMNGVLTVKKEINRETVPTYTLTIRASDRGSPM 1391 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 +S + + + D+ND+PPVF S + ENS T++ + A D D G NAV+ YSI Sbjct: 1392 MTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSI 1451 Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTD 786 G+D F + + G ++T LD+E + +Y L + A V I V + Sbjct: 1452 ISGNDEKRFKINSTSGV----IMTTTPLDFEE-KSQYGLEVTATDSKYTAKTNVTIRVIN 1506 Query: 787 VNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETT 846 +ND P + ++ +V A D D L Y I+ G +++ +++ + Sbjct: 1507 LNDITPAFTQQNYTASVRENSPTSTSVVKVSASDRDSFGSLSYSIVGGKDSDKFSIDQRS 1566 Query: 847 GSMTLSPQLNTNVPKLATMEVSVTDGVN-EIKAMMQLSVRLITE 889 G ++ + L+ + L ++V VTD N + + ++++++ E Sbjct: 1567 GIISTADVLDRELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDE 1610 Score = 440 bits (1085), Expect = e-121 Identities = 283/867 (32%), Positives = 447/867 (51%), Gaps = 56/867 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I +LD ND+ PVF QY ASV E + G ++T+ A+D+D G NA++ Y+ T+ Sbjct: 258 EIEILDVNDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSF---TSGN 314 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N F +D +G + SLD E+ + Y + + TD+ SP Sbjct: 315 TN----------------HAFTLDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSP---P 355 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L+ T+ + +N+ D NDN P FS Y V E + P ++ ATD D N A+ + Sbjct: 356 LTDTSHLLINVNDINDNPPVFSPSAYQSRVKE-----NTPAGTQVSATDRDSSTNGALVF 410 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 II GN F+ID +G +S+ K+ DYE Y L ++A+D G P + +T Q+ I I D Sbjct: 411 GIIKGNDDGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVKYDTAQVTIFIED 470 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 VND++P F S + + + E+ IG ++V V A D D G L Y + +GNV Sbjct: 471 VNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRL----ISGNVKGAF 526 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 ID SG + S +LDRET Y L V A DGG RS++ F G Sbjct: 527 NIDANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDINDNSPIFQ-G 585 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 Y ++E PG + + ATDAD+ + + FSI + GLIT+ L Sbjct: 586 PYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSDNTDVFSINTST--GLITLKTQL 643 Query: 430 DFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 D++++ +Y++TV+A D G RS +V++ + D N+ P F + YT +V E+ G Sbjct: 644 DYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVA 703 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 V V+ATD+D G N +I+YS+ S NE +A F ++ TG ITT LDRET++ Y Sbjct: 704 VCYVTATDADSGANGKISYSILS--GNENMA-----FAMDRFTGEITTRVPLDRETIASY 756 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 LT+ A DG + T V IS+ D NDN+P F NI ED+ GT V Q+ ATD Sbjct: 757 SLTINADDGSLVRFMAATTVNISIADENDNQPTFTGP-SRFNISEDSPTGTRVGQLTATD 815 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 D+G NG + Y + + SF +DP SG++ LDRE++ ++ L A D G+P Q Sbjct: 816 RDIGPNGAVTYAI-ISGNQGNSFQLDPRSGILSVRSTLDRETIPSYTLVVKASDAGSPQQ 874 Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 S T +H+ + D+ND+ P FE + I E++ + +T+ +++ D DEG N + S+ Sbjct: 875 SITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITLSL- 933 Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILV 784 G+ S++F++++ +++ LDYE+ Y+L + A SP +V+I + Sbjct: 934 SGEGSDNFTIDS-----TGFVLSKTPLDYET-TAAYQLTVTARDGGSPSKSATAQVKITI 987 Query: 785 TDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNE 844 +VNDN P + + +D ++ A D+D T L + I+ GN + +++ Sbjct: 988 INVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDSDGT-PLTFDIVEGNAGSSFKIDQ 1046 Query: 845 TTGSMTLSPQLNTNVPKLATMEVSVTD 871 ++G ++++ +L+ T+ V T+ Sbjct: 1047 SSGLISVAKRLDRETTANYTLVVRATE 1073 Score = 416 bits (1024), Expect = e-114 Identities = 290/861 (33%), Positives = 431/861 (50%), Gaps = 63/861 (7%) Query: 2 SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 S+ IH ++VLD ND++P FE + +RE AS +TVL +K D+D G N + Sbjct: 875 SITASIH--VSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQVKVEDKDEGSNGAITL- 931 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121 +L+ E + D F ID +G +L++ LD E A Y + V A D Sbjct: 932 -------SLSGEGS------------DNFTIDS-TGFVLSKTPLDYETTAAYQLTVTARD 971 Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181 SP S+TA + + II+ NDN P F S+ ED+++ N + K+ ATD+D Sbjct: 972 GGSPSK---SATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAI--NTHVVKLNATDSD- 1025 Query: 182 GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 + + + I+ GN F ID SG +S+ K LD E +Y LV+RA + GS S Sbjct: 1026 --GTPLTFDIVEGNAGSSFKIDQSSGLISVAKRLDRETTANYTLVVRATETGSQGESVYN 1083 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 I + DVNDNAP F + +S+ EN+PIG ++ +V A D DEG NA++TY ++ D Sbjct: 1084 NATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTYELSVGDT 1143 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 + ++P +G V T LDRE QA Y L VTA D G P +SA A Sbjct: 1144 S-----KFEVNPATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQSAVAAITLTINDLND 1198 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419 F +Y + + E+ G+ ++ + A+D D + R+ Y I GN F I S G Sbjct: 1199 NSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSIISGNHGNAFRIDSTTG 1258 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTAS 477 R ITV +D + Y LT+SA DSG TA V I + D N+ +P+F + + Sbjct: 1259 R--ITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASNETSYG 1316 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 + E IG+ V VV+ATD D G NAQ+ YS+ V F IN G +T K Sbjct: 1317 IDEGVSIGSRVAVVTATDRDEGSNAQVFYSI--------VRGDTSAFAINAMNGVLTVKK 1368 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 ++RET+ Y LT+ A D G P ++ ++ + V DVNDN PVF Q Y ++ E++ Sbjct: 1369 EINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQS 1428 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 TSV V A D+DVG N + Y + +E F I+ SGVI T LD E + + L+ Sbjct: 1429 TSVLTVAADDSDVGANAVLRYSI-ISGNDEKRFKINSTSGVIMTTTPLDFEEKSQYGLEV 1487 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A D +++ V I++ ++ND P F T + ENSP T++ ++ A D D Sbjct: 1488 TATDSKYTAKTN---VTIRVINLNDITPAFTQQNYTASVRENSPTSTSVVKVSASDRDSF 1544 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND 777 + + YSI GG DS+ FS++ R G ++D + S V A +PPL N Sbjct: 1545 GS--LSYSIVGGKDSDKFSIDQRSGI--ISTADVLDRELVSLYAIQVRVTDAGNPPLSNL 1600 Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGN 835 V I + D NDN+P + ++ P ++ A DAD ++ Y LS N Sbjct: 1601 TWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDADEGTNARITYN-LSRN 1659 Query: 836 NANLILLNETTGSMTLSPQLN 856 +A ++ ++G +TL+ L+ Sbjct: 1660 DA--FMIGASSGVITLAQPLD 1678 Score = 413 bits (1018), Expect = e-113 Identities = 289/850 (34%), Positives = 430/850 (50%), Gaps = 62/850 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D NDHSPVF Y + E G+TV+T+ ATD D G +EY L++ + Sbjct: 466 IFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEY--RLISGN-- 521 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 V+ F ID SG++ + LDRE Y++ V+A D S + R Sbjct: 522 ---------------VKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARDGGS--TSRS 564 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SST + + + D NDN P F + Y V E S + I ++ ATDAD +N +RYA Sbjct: 565 SST-RVTIALQDINDNSPIF-QGPYVFRVSE--SSSPGHQIGQVAATDADDSSNGDVRYA 620 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + NT + FSI++ +G ++L LDYE+ Y + + A+DGG+PSRS+ T + + + DV Sbjct: 621 -LSDNTDV-FSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDV 678 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P+F SL+ +V EN+ G ++ V A DAD G N +++Y++ +GN ++ Sbjct: 679 NDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSI----LSGNENMAFA 734 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 +D +G + T LDRET A Y L + A D G R AT G Sbjct: 735 MDRFTGEITTRVPLDRETIASYSLTINA-DDGSLVRFMAATTVNISIADENDNQPTFTGP 793 Query: 371 YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 ++ED P GT V LTATD D + + Y I GN F + ++ G+++V Sbjct: 794 SRFNISEDSPTGTRVGQLTATDRDIGPNGAVTYAIISGNQGNSFQLDPRS--GILSVRST 851 Query: 429 LDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD + Y L V A+D+G +S TA + +++ D N+ AP FE + ++ + EDA + + Sbjct: 852 LDRETIPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHS 911 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 TVL V D D G N IT SLS E S+ F I+ TG + + LD ET + Sbjct: 912 TVLQVKVEDKDEGSNGAITLSLSGEGSD--------NFTID-STGFVLSKTPLDYETTAA 962 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y LTVTARDGG PS S T V+I++++VNDN P F +I ED + T V ++ AT Sbjct: 963 YQLTVTARDGGSPSKSATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNAT 1022 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D+D + +++ + SF ID +SG+I K LDRE+ A + L A + G+ Sbjct: 1023 DSD---GTPLTFDI-VEGNAGSSFKIDQSSGLISVAKRLDRETTANYTLVVRATETGSQG 1078 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 +S I++ D+ND+ PVF + EN PIG T+ ++ A D DEG NA V Y + Sbjct: 1079 ESVYNNATIRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTYEL 1138 Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEIL 783 GD S F + G + T LD E + Y L + A P + + Sbjct: 1139 SVGDTS-KFEVNPATGL----VTTKRPLDRED-QASYSLRVTAMDHGKPSQSAVAAITLT 1192 Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLIL 841 + D+NDN+P + ++ RV A D D ++ Y I+SGN+ N Sbjct: 1193 INDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSIISGNHGNAFR 1252 Query: 842 LNETTGSMTL 851 ++ TTG +T+ Sbjct: 1253 IDSTTGRITV 1262 Score = 412 bits (1015), Expect = e-113 Identities = 289/869 (33%), Positives = 433/869 (49%), Gaps = 66/869 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+V D ND++P F + Y ++RE + V + ATD+D G NA + Y++ Sbjct: 58 IDVKDENDNAPEFPLNSYVFNIREN-TPAAQVAIVTATDRDSGTNAAITYSL-------- 108 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 ++ F ++ ++G + T LD E YT+ + A D Sbjct: 109 -------------FSGENKFMMNSKTGEIRTVTPLDHETKDSYTMRISAFDGK------- 148 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +T + + D NDN P F+ Y V ED++V ++ ++ A D DVG N+ + Y+ Sbjct: 149 HTTFVPLITVDDVNDNAPFFALSVYKTGVYEDVAV--GSIVRQLTAVDLDVGINARLSYS 206 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 ++ G+T F++DS G + D E SY++ +RAQDGGSPSRS + I I DV Sbjct: 207 LVSGDTS-YFTVDS-QGVIRTKGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDV 264 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F ++ + SV E+V IG ++V V A D D G NA+L Y+ T +GN + T Sbjct: 265 NDNRPVFSSAQYTASVDEDVAIGAAMVTVTASDKDNGNNADLRYSFT----SGNTNHAFT 320 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 +D +G V S LD E ++ Y L ++ TD G PP + T+ F P Sbjct: 321 LDAVTGVVTVSRSLDFEQRSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSA 380 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 Y+ + E+ P GT V+ T D+ + L + I GN G F+I G+I++A+ D Sbjct: 381 YQSRVKENTPAGTQ-VSATDRDSSTNGALVFGIIKGNDDGVFTI--DGSTGIISIAKSPD 437 Query: 431 FKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 ++ + RY LTV A D G + DTA V I I D N+++PVF + Y+ + E IG+TV Sbjct: 438 YENKTRYDLTVQARDRGVPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTV 497 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 + V+ATD D G ++ Y L S A F I+ +G+I + LDRET Y Sbjct: 498 VTVTATDLDSGPRGRLEYRLISGNVKGA-------FNIDANSGSIRVSSELDRETTPSYS 550 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 L V ARDGG S S +T V I++ D+NDN P+F Q Y + E + G + QV ATDA Sbjct: 551 LQVEARDGGSTSRSSSTRVTIALQDINDNSPIF-QGPYVFRVSESSSPGHQIGQVAATDA 609 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 D NG + Y L D + F I+ ++G+I LD E + + A DGGTP +S Sbjct: 610 DDSSNGDVRYAL--SDNTD-VFSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRS 666 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 S +V + ++D+ND+PP F T + EN G + + A D D G N + YSI Sbjct: 667 SLTVVKVMVDDVNDNPPQFAKSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILS 726 Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL---WNDVRVEILVT 785 G+++ +F+++ G E+ T V LD E+ Y L I A L V I + Sbjct: 727 GNENMAFAMDRFTG----EITTRVPLDRET-IASYSLTINADDGSLVRFMAATTVNISIA 781 Query: 786 DVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADV--TDKLQYRILSGNNANLILL 842 D NDN P FN +D P G G++ A D D+ + Y I+SGN N L Sbjct: 782 DENDNQPTFTG-PSRFNISEDS-PTGTRVGQLTATDRDIGPNGAVTYAIISGNQGNSFQL 839 Query: 843 NETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + +G +++ L+ T+ V +D Sbjct: 840 DPRSGILSVRSTLDRETIPSYTLVVKASD 868 Score = 407 bits (1001), Expect = e-111 Identities = 274/797 (34%), Positives = 409/797 (51%), Gaps = 51/797 (6%) Query: 87 QDVFRIDGRSGALLTRA-SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145 Q +F ID +G++ T DRE +RY + V A D A+ + +++ D+ND Sbjct: 9 QGMFTIDSSTGSITTTGRKFDRESESRYRLTVLAQDAANRCH---KGRTVVVIDVKDEND 65 Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205 N P+F +Y ++ E+ T +A + ATD D G N+AI Y++ G + F ++S Sbjct: 66 NAPEFPLNSYVFNIREN---TPAAQVAIVTATDRDSGTNAAITYSLFSGENK--FMMNSK 120 Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265 +G++ V LD+E SY + I A DG + T LI + DVNDNAP F S+++ Sbjct: 121 TGEIRTVTPLDHETKDSYTMRISAFDG----KHTTFVPLITVDDVNDNAPFFALSVYKTG 176 Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325 V E+V +G + ++ A D D G+NA L+Y++ D + T+D + G + T G D Sbjct: 177 VYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGDTS-----YFTVDSQ-GVIRTKGAFD 230 Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 RET+A YQ+ + A DGG P RS AT F QY + ED G + Sbjct: 231 RETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVAIGAAM 290 Query: 386 VTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443 VT+TA+D D N L Y T GNT F++ + G++TV++ LDF+Q Y L +S Sbjct: 291 VTVTASDKDNGNNADLRYSFTSGNTNHAFTLDAVT--GVVTVSRSLDFEQRSSYALGLSV 348 Query: 444 TDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501 TD G +DT+ + IN+ D N+ PVF + Y + V E+ P GT VSATD D N Sbjct: 349 TDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGTQ---VSATDRDSSTN 405 Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL 561 + + + + D F I+ TG I+ K D E + Y LTV ARD GVP Sbjct: 406 GALVFGIIK-------GNDDGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVK 458 Query: 562 SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621 DT V I + DVND+ PVF Y+ I E ++G++V V ATD D G GR+ Y L Sbjct: 459 YDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLEYRL- 517 Query: 622 PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681 +G+F ID SG IR + LDRE+ ++ L+ A DGG+ +SS+ V I ++DIN Sbjct: 518 ISGNVKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIALQDIN 577 Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741 D+ P+F+ F +SE+S G IG++ A D D+ N V Y++ D+++ FS+ T Sbjct: 578 DNSPIFQGP-YVFRVSESSSPGHQIGQVAATDADDSSNGDVRYAL--SDNTDVFSINTST 634 Query: 742 GSDKAELVTM-VDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDF 797 G L+T+ LDYE + +Y + + A +P + V+++V DVNDN P Sbjct: 635 G-----LITLKTQLDYEK-KTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFAKS 688 Query: 798 QIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQL 855 ++ V A DAD K+ Y ILSGN ++ TG +T L Sbjct: 689 LYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNENMAFAMDRFTGEITTRVPL 748 Query: 856 NTNVPKLATMEVSVTDG 872 + ++ ++ DG Sbjct: 749 DRETIASYSLTINADDG 765 Score = 402 bits (991), Expect = e-110 Identities = 274/787 (34%), Positives = 405/787 (51%), Gaps = 56/787 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I VLD ND++PVF Y S+ E G TV + ATD+D G+NA+V Y EL DT Sbjct: 1087 IRVLDVNDNAPVFNPGSYAKSLHENLPIGQTVAKVTATDRDEGENAKVTY--ELSVGDTS 1144 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F ++ +G + T+ LDRE A Y++ V A D P Sbjct: 1145 K------------------FEVNPATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQ--- 1183 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+ A I + I D NDN PQFS+ YT++V E+ + N I ++ A+D D GAN + Y+ Sbjct: 1184 SAVAAITLTINDLNDNSPQFSQSKYTLTVTENTANGSN--ILRVLASDPDAGANGRVTYS 1241 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 II GN F IDS +G +++V +D E + SY L I A+D G P +T + I + D Sbjct: 1242 IISGNHGNAFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADE 1301 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN+P F ++ + E V IG + V A D DEG NA++ Y++ D + Sbjct: 1302 NDNSPIFASNETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIVRGDTSA-----FA 1356 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I+ +G + +++RET Y L + A+D G P ++ F Sbjct: 1357 INAMNGVLTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQS 1416 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQP 428 Y + E+ T V+T+ A D+D L Y I GN RF I S +G +I P Sbjct: 1417 YIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSIISGNDEKRFKINSTSG--VIMTTTP 1474 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 LDF+++ +Y L V+ATDS + T V I + + N+ P F YTASV E++P T+V Sbjct: 1475 LDFEEKSQYGLEVTATDSKYTAKTN-VTIRVINLNDITPAFTQQNYTASVRENSPTSTSV 1533 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 + VSA+D D ++YS+ ++ +F I+ ++G I+T +LDRE +S Y Sbjct: 1534 VKVSASDRDSF--GSLSYSIVGGKDSD-------KFSIDQRSGIISTADVLDRELVSLYA 1584 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 + V D G P LS+ T V I ++D NDN P F Y+++I+E++ + ++ ATDA Sbjct: 1585 IQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDA 1644 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 D G N RI Y L D +F+I +SGVI + LDRE+ +T+DL A D GTPPQ+ Sbjct: 1645 DEGTNARITYNLSRND----AFMIGASSGVITLAQPLDRENKSTYDLAIQARDHGTPPQA 1700 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 S++ + + + DIND P+ S L + EN P T + I A D D G NA + +S+ Sbjct: 1701 SSITIRVTVIDINDHRPLINSSSLRGSVRENQPKETHVMRILASDADTGLNAELTFSLLS 1760 Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVT 785 + + F+L+ G ++ T V LD E + Y L I A +P L + V I V Sbjct: 1761 NEHKSVFTLDNTTG----DISTKVPLDREQ-QAVYTLRIGVADKGNPSLSSVADVIIDVI 1815 Query: 786 DVNDNAP 792 D +DN P Sbjct: 1816 DEDDNCP 1822 Score = 384 bits (945), Expect = e-104 Identities = 281/877 (32%), Positives = 429/877 (48%), Gaps = 73/877 (8%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 H INV D ND+ PVF Y++ V+E +GT V ATD+D N + + I Sbjct: 361 HLLINVNDINDNPPVFSPSAYQSRVKENTPAGTQV---SATDRDSSTNGALVFGI----- 412 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 + D VF IDG +G + S D E RY + V+A D+ PV Sbjct: 413 --IKGND------------DGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRGVPVK 458 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 TA + + I D ND+ P FS Y+ + E S + + ATD D G + Sbjct: 459 ---YDTAQVTIFIEDVNDHSPVFSPSNYSKQIPE--STVIGSTVVTVTATDLDSGPRGRL 513 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 Y +I GN + F+ID+ SG + + LD E SY L + A+DGGS SRS++T++ I + Sbjct: 514 EYRLISGNVKGAFNIDANSGSIRVSSELDRETTPSYSLQVEARDGGSTSRSSSTRVTIAL 573 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 +D+NDN+P + + VSE+ G+ I +V A DAD+ N ++ Y ++D N D+ Sbjct: 574 QDINDNSP-IFQGPYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSD-----NTDV 627 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 +I+ +G + QLD E + +Y + VTA DGG P RS+ F Sbjct: 628 -FSINTSTGLITLKTQLDYEKKTQYMVTVTAKDGGTPSRSSLTVVKVMVDDVNDNPPQFA 686 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITV 425 Y + E+ G V +TATDAD + ++ Y I GN F++ G IT Sbjct: 687 KSLYTCTVGENLAAGVAVCYVTATDADSGANGKISYSILSGNENMAFAMDRFTGE--ITT 744 Query: 426 AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 PLD + Y LT++A D V I+I D N+ P F P ++ ED+P Sbjct: 745 RVPLDRETIASYSLTINADDGSLVRFMAATTVNISIADENDNQPTF-TGPSRFNISEDSP 803 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 GT V ++ATD D+G N +TY++ S + F ++P++G ++ LDRET Sbjct: 804 TGTRVGQLTATDRDIGPNGAVTYAIIS-------GNQGNSFQLDPRSGILSVRSTLDRET 856 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 + Y L V A D G P S T + +SV+DVNDN P F++ L++ I EDA V ++V QV Sbjct: 857 IPSYTLVVKASDAGSPQQSITASIHVSVLDVNDNAPRFEKSLFSGEIREDASVHSTVLQV 916 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 D D G NG I L + + +F ID ++G + + LD E+ A + L A DGG Sbjct: 917 KVEDKDEGSNGAITLSLSGEGSD--NFTID-STGFVLSKTPLDYETTAAYQLTVTARDGG 973 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 +P +S+T V I I ++ND+ P F S I E+ I T + ++ A D D P + Sbjct: 974 SPSKSATAQVKITIINVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDSDGTP---LT 1030 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVIRAA-----SPPLWND 777 + I G+ +SF ++ G L+++ LD E+ Y LV+RA ++N+ Sbjct: 1031 FDIVEGNAGSSFKIDQSSG-----LISVAKRLDRET-TANYTLVVRATETGSQGESVYNN 1084 Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTD--KLQYRILSG 834 + +L DVNDNAPV + +++ P+G +V A D D + K+ Y + G Sbjct: 1085 ATIRVL--DVNDNAPVFNPGSYAKSLHEN-LPIGQTVAKVTATDRDEGENAKVTYELSVG 1141 Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + + +N TG +T L+ ++ V+ D Sbjct: 1142 DTSK-FEVNPATGLVTTKRPLDREDQASYSLRVTAMD 1177 Score = 382 bits (941), Expect = e-104 Identities = 277/891 (31%), Positives = 447/891 (50%), Gaps = 66/891 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I +++ ND+ P F S+ E + T V+ L ATD D T ++V + Sbjct: 984 KITIINVNDNVPSFVSPAQVTSIPEDVAINTHVVKLNATDSD-----GTPLTFDIVEGNA 1038 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + F+ID SG + LDRE A YT++V+AT+ S + Sbjct: 1039 GSS-----------------FKIDQSSGLISVAKRLDRETTANYTLVVRATETGSQ-GES 1080 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + + ATI V +D NDN P F+ +Y S+ E++ + +AK+ ATD D G N+ + Y Sbjct: 1081 VYNNATIRV--LDVNDNAPVFNPGSYAKSLHENLPI--GQTVAKVTATDRDEGENAKVTY 1136 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 + G+T +F ++ +G V+ + LD E SY L + A D G PS+S + + I D Sbjct: 1137 ELSVGDTS-KFEVNPATGLVTTKRPLDREDQASYSLRVTAMDHGKPSQSAVAAITLTIND 1195 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 +NDN+P+F S + +V+EN G +I+RV A D D G N +TY++ +GN Sbjct: 1196 LNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSII----SGNHGNAF 1251 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 ID +G + G +DRE A Y L ++A D G PP +TA F Sbjct: 1252 RIDSTTGRITVVGVVDREALASYNLTISAKDSGVPPWVSTAFVAITVADENDNSPIFASN 1311 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 + + E G+ V +TATD DE + ++ Y I G+T F+I + NG ++TV + Sbjct: 1312 ETSYGIDEGVSIGSRVAVVTATDRDEGSNAQVFYSIVRGDTSA-FAINAMNG--VLTVKK 1368 Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIG 485 ++ + Y LT+ A+D G T+ ++ + D N+ PVF + Y SV E++ Sbjct: 1369 EINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDVNDNPPVFNSQSYIGSVRENSAQS 1428 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 T+VL V+A DSDVG NA + YS+ S + +++F IN +G I T LD E S Sbjct: 1429 TSVLTVAADDSDVGANAVLRYSIIS-------GNDEKRFKINSTSGVIMTTTPLDFEEKS 1481 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 Y L VTA D + T+V I V+++ND P F QQ YTA++ E++ TSV +V A Sbjct: 1482 QYGLEVTATDS---KYTAKTNVTIRVINLNDITPAFTQQNYTASVRENSPTSTSVVKVSA 1538 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 +D D G + Y + ++ F ID SG+I T LDRE V+ + ++ D G P Sbjct: 1539 SDRDSF--GSLSYSI-VGGKDSDKFSIDQRSGIISTADVLDRELVSLYAIQVRVTDAGNP 1595 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 P S+ V IKI D ND+ P F+S + I ENS + ++ A D DEG NA + Y+ Sbjct: 1596 PLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFSFKLAATDADEGTNARITYN 1655 Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEI 782 + D +F + G+ + LD E+ + Y+L I+A +PP + + + + Sbjct: 1656 LSRND---AFMI----GASSGVITLAQPLDREN-KSTYDLAIQARDHGTPPQASSITIRV 1707 Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLI 840 V D+ND+ P++ + + ++ R+ A DAD + +L + +LS + ++ Sbjct: 1708 TVIDINDHRPLINSSSLRGSVRENQPKETHVMRILASDADTGLNAELTFSLLSNEHKSVF 1767 Query: 841 LLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEE 890 L+ TTG ++ L+ + T+ + V D G + ++ + + +I E+ Sbjct: 1768 TLDNTTGDISTKVPLDREQQAVYTLRIGVADKGNPSLSSVADVIIDVIDED 1818 Score = 351 bits (862), Expect = 2e-94 Identities = 227/707 (32%), Positives = 363/707 (51%), Gaps = 47/707 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND+SP F +Y +V E ++G+ +L + A+D D G N V Y+I ++ + Sbjct: 1191 LTINDLNDNSPQFSQSKYTLTVTENTANGSNILRVLASDPDAGANGRVTYSI--ISGNHG 1248 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N FRID +G + +DRE +A Y + + A D P Sbjct: 1249 N-----------------AFRIDSTTGRITVVGVVDREALASYNLTISAKDSGVPP---W 1288 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 STA + + + D+NDN P F+ + +DE +S+ +A + ATD D G+N+ + Y+ Sbjct: 1289 VSTAFVAITVADENDNSPIFASNETSYGIDEGVSIGSR--VAVVTATDRDEGSNAQVFYS 1346 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I+ G+T F+I++++G +++ K ++ E V +Y L IRA D GSP ++ +L + + DV Sbjct: 1347 IVRGDTSA-FAINAMNGVLTVKKEINRETVPTYTLTIRASDRGSPMMTSDKELTVVVNDV 1405 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F + + SV EN S++ V A D+D G NA L Y++ +GN + Sbjct: 1406 NDNPPVFNSQSYIGSVRENSAQSTSVLTVAADDSDVGANAVLRYSII----SGNDEKRFK 1461 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I+ SG + T+ LD E +++Y L VTATD +A F Sbjct: 1462 INSTSGVIMTTTPLDFEEKSQYGLEVTATDS---KYTAKTNVTIRVINLNDITPAFTQQN 1518 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 Y + E+ P T VV ++A+D D L Y I GG +FSI ++G +I+ A LD Sbjct: 1519 YTASVRENSPTSTSVVKVSASDRDSFGSLSYSIVGGKDSDKFSIDQRSG--IISTADVLD 1576 Query: 431 FKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 + Y + V TD+G S+ V I I D N+ +P F+++ Y++S+ E++ + Sbjct: 1577 RELVSLYAIQVRVTDAGNPPLSNLTWVTIKILDENDNSPKFDSSSYSSSILENSAPSSFS 1636 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 ++ATD+D G NA+ITY+LS N+A F+I +G IT + LDRE S Y Sbjct: 1637 FKLAATDADEGTNARITYNLSR---NDA-------FMIGASSGVITLAQPLDRENKSTYD 1686 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 L + ARD G P + + + ++V+D+ND+ P+ ++ E+ T V ++ A+DA Sbjct: 1687 LAIQARDHGTPPQASSITIRVTVIDINDHRPLINSSSLRGSVRENQPKETHVMRILASDA 1746 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 D GLN + + L + + F +D +G I T LDRE A + L+ D G P S Sbjct: 1747 DTGLNAELTFSL-LSNEHKSVFTLDNTTGDISTKVPLDREQQAVYTLRIGVADKGNPSLS 1805 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 S V I + D +D+ P F+ ISE+ P G +I ++ A D D Sbjct: 1806 SVADVIIDVIDEDDNCPRFQPTEYNVTISESLPRGASIVQVTARDID 1852 Score = 329 bits (809), Expect = 6e-88 Identities = 224/692 (32%), Positives = 346/692 (50%), Gaps = 40/692 (5%) Query: 189 YAIIGGNTQMQFSIDSLSGDVSLV-KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 Y+I+ GN Q F+IDS +G ++ + D E YRL + AQD + T ++I++ Sbjct: 1 YSIMDGNDQGMFTIDSSTGSITTTGRKFDRESESRYRLTVLAQDAANRCHKGRTVVVIDV 60 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 +D NDNAP F + + ++ EN P + V A D D G NA +TY++ ++G + Sbjct: 61 KDENDNAPEFPLNSYVFNIRENTPAA-QVAIVTATDRDSGTNAAITYSL----FSG--EN 113 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 ++ ++G + T LD ET+ Y + ++A DG + T F Sbjct: 114 KFMMNSKTGEIRTVTPLDHETKDSYTMRISAFDG----KHTTFVPLITVDDVNDNAPFFA 169 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITV 425 Y+ + ED G+ V LTA D D + RL Y + G+T F++ SQ G+I Sbjct: 170 LSVYKTGVYEDVAVGSIVRQLTAVDLDVGINARLSYSLVSGDT-SYFTVDSQ---GVIRT 225 Query: 426 AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 D + + Y + + A D G RS A V+I I D N+ PVF +A YTASV ED Sbjct: 226 KGAFDRETKASYQVALRAQDGGSPSRSGQATVEIEILDVNDNRPVFSSAQYTASVDEDVA 285 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 IG ++ V+A+D D G NA + YS +S +N A F ++ TG +T ++ LD E Sbjct: 286 IGAAMVTVTASDKDNGNNADLRYSFTSGNTNHA-------FTLDAVTGVVTVSRSLDFEQ 338 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 S Y L ++ D G P L+DT+ + I+V D+NDN PVF Y + + E+ GT QV Sbjct: 339 RSSYALGLSVTDRGSPPLTDTSHLLINVNDINDNPPVFSPSAYQSRVKENTPAGT---QV 395 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 ATD D NG + + + K ++G F ID ++G+I K+ D E+ +DL A D G Sbjct: 396 SATDRDSSTNGALVFGI-IKGNDDGVFTIDGSTGIISIAKSPDYENKTRYDLTVQARDRG 454 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 P + T V I IED+ND PVF + I E++ IG+T+ + A D D GP + Sbjct: 455 VPVKYDTAQVTIFIEDVNDHSPVFSPSNYSKQIPESTVIGSTVVTVTATDLDSGPRGRLE 514 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRV 780 Y + G+ +F+++ GS + +LD E+ Y L + A S + RV Sbjct: 515 YRLISGNVKGAFNIDANSGSIRVS----SELDRET-TPSYSLQVEARDGGSTSRSSSTRV 569 Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLI 840 I + D+NDN+P+ + +F + P G+V A DAD + R +N ++ Sbjct: 570 TIALQDINDNSPIFQG-PYVFRVSESSSPGHQIGQVAATDADDSSNGDVRYALSDNTDVF 628 Query: 841 LLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 +N +TG +TL QL+ + V+ DG Sbjct: 629 SINTSTGLITLKTQLDYEKKTQYMVTVTAKDG 660 >UniRef50_Q6W4W6 Cluster: CHz-cadherin; n=19; Euteleostomi|Rep: CHz-cadherin - Gallus gallus (Chicken) Length = 2819 Score = 468 bits (1153), Expect = e-129 Identities = 452/1650 (27%), Positives = 712/1650 (43%), Gaps = 161/1650 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NV D ND+ P F YE SV EGA GT+V+ + ATD D G + +V Y I L A Sbjct: 1031 VNVTDVNDNVPFFVSSNYEVSVPEGADVGTSVVQVLATDLDSGLHGQVRYFI-LKDAS-- 1087 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 ED F I+ +G + T AS DREK A Y + V++ D + + Sbjct: 1088 --ED------------YQFFTIEPETGIISTHASFDREKRASYLIEVQSQDSSESARPGV 1133 Query: 131 -----SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 + TA + + + D NDN P F + Y VSVDED V +PV+ A D D GAN+ Sbjct: 1134 HGHPNTDTAYVRIFVSDVNDNAPAFPQPVYEVSVDEDRDV-GSPVVT-ATADDRDEGANA 1191 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 +RY I GNT+ F ++ +G V +V++LDYE+ + Y L + A DG N T ++I Sbjct: 1192 KLRYQITSGNTKGVFDVEPEAGTVFIVQSLDYEEEQRYELRLVASDG---KWENHTLIII 1248 Query: 246 NIRDVNDNAPRFYTSLFQESVSENV-PIGYSIVRVQAYDADEGVNAE-LTYTMTDKDYTG 303 N+ + ND AP F + + S+ E + + +++V A D D+ + L+Y++ + Sbjct: 1249 NVVNKNDEAPVFTQNEYHGSILEELTDLPVFVLKVSATDPDQEADQNALSYSL----HGQ 1304 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 +I+ +G + + +LDRE ++ ++ LV ATD + A Sbjct: 1305 GAGSEFSINENTGEISANRRLDREKRSTWRFLVLATDESGEGLTGFADVVIEVRDTNDNA 1364 Query: 364 XXFM---PGQYEVELAEDEPPGTPVVTLTATDADEDN---------RLHYEITGGNTRGR 411 F+ + + ED P T V+ +TA D D+ R+ + Sbjct: 1365 PLFLCVSDDCFMGYVPEDSPADTAVMEMTAVDLDDPKASTHAVLTYRIIQNVQNEINLNL 1424 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN 471 FSI +G + TV LD ++ +Y+L V A D GG + T I +TD N++APVF Sbjct: 1425 FSINPVSGT-ICTVLGSLDREKVDKYLLVVEARDGGGLTGTGTATILVTDVNDHAPVFLQ 1483 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 YTA V E+A I T V VVSA D D G NA +T+S+ + + + G Sbjct: 1484 RIYTAFVSENASINTEVAVVSAMDRDEGENAMVTFSI---LDGDNDCKFSIETDKGNNCG 1540 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY-TANI 590 I K +D E + +T + + S V I V D ND+ PVF Q Y A++ Sbjct: 1541 FIHLRKQIDFEKPHERVFNLTLKAEDMDFFSIAHCV-IYVEDANDHAPVFYPQFYEVASL 1599 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650 ED VGT V QV A D D GLNGR + L K G F + + G + LD E+V Sbjct: 1600 AEDVPVGTKVVQVSAVDLDSGLNGRFSFHLLNKSDPGGQFSV-ASDGWVIVAGVLDHETV 1658 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN--SPIGTTIGE 708 + L +A D G PP + + V + ++D+ND+ P FE+ + EN SP + E Sbjct: 1659 TQYQLIVIATDMGQPPLACSATVLVTLQDVNDNGPEFEAH-YNPVVWENTASPQSVQMNE 1717 Query: 709 ----IRAHDPDEGPNAV--VHYSIKGGDDSNSFSLET-RQGSDKAELVTMVDLDYESPRK 761 + A D D N + + D +F L+ GS + D + Sbjct: 1718 TSTLLYAKDRDTAANGAPFSFHLLSNFDSLGNFHLQDFHNGSALLTALHTFDREVHKVFH 1777 Query: 762 KYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDA 821 L+ + PP+ + + + + D ND+ + + +Y P G+V A D Sbjct: 1778 LPILITDSGIPPMSSTNTLTVNIGDQNDHPHSAGYMECLIYSYDGILPTTVLGQVLAPDG 1837 Query: 822 DVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGV-NEIKAMM 880 D D+ Y+ G + +LN+ +G +T+ P ++V V DGV ++ + + Sbjct: 1838 DDWDRKIYQ-FEGKTSRYFILNDNSGLLTIK---EGTPPGTYNIKVRVIDGVWPDVVSTV 1893 Query: 881 QLSVRLITEEMLLNSITVRLNDMTAEQFLSPL------LGFFIDGLAAIIPCPKENIYIF 934 ++ V+ I ++ L N+ ++++ D T E+F+S L+ II EN++IF Sbjct: 1894 KVIVKEIKDDALHNAGSLQIKDTTPEEFISQFPEKESKYNQLKKLLSEIISVQLENVHIF 1953 Query: 935 SVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQV 994 SV + G ++V F+ P P+Y L V R L + + + Sbjct: 1954 SVLKSSQTRG--VDVWFAVYGP-----------PYYKAEKLNGNVAASRAWLENILDINI 2000 Query: 995 LPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQC-PEGFTGV 1053 + CV C + C++ + + + S+ + ++S C C + Sbjct: 2001 TQIGIDECVTANCTHSSGCISKYEHSHVPTITTAGSISLVSVTVLSSALCSCAARESPHL 2060 Query: 1054 NCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCELRARSFPVS 1113 +C + T C +G CV + G C+ CS A + C+ SF Sbjct: 2061 SCSSYQTNP----------CLNGGTCV-DTDLGYRCR-CS--ANFHGPDCQQTKHSFKGH 2106 Query: 1114 SFLTFPGLKRRHRIHLKLKFATQTTSGLLLY-----NGRYNERHDFLALELVSSEAGRGG 1168 + FP LK + L+F T+ GLLLY G+ + DF+ALEL GG Sbjct: 2107 GYAWFPPLKPCFESRISLEFITEVADGLLLYQGPVARGQPGQLEDFIALEL------SGG 2160 Query: 1169 GPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKVLSLAGAADFG 1228 P L S S G +++ + NV D WH ++I+ + + ++LD C S+ + Sbjct: 2161 VPALTVSHSSGELFLQLSKKVNVADRRWHNIKIKSDGKKVKLVLDHCTNG-SVRHSGSVD 2219 Query: 1229 LKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNI-P-SSFQVKNKDFVGCIS 1286 K + + + + + T + R PLQ+GG+ I P Q + + FVGCI Sbjct: 2220 KKISQVDLS-ACEASEETMGTWSMSRIFSGHQPLQLGGVKKILPYRDSQKRFRGFVGCIR 2278 Query: 1287 DFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSA---PCYNGAECSDLWDTYICDCKEGH 1343 + +D K DL + GC C SA C C W + CDC G+ Sbjct: 2279 NVVVDTKVYDLEHPAESLNSSPGCILTDEMCQSAGMVSCGVHGRCVGDWGFFHCDCAPGY 2338 Query: 1344 TGKDCADSTGPPWRFGGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMSIQLKSG--- 1400 G C D P W FG D + + P L L +RTR + ++S+ G Sbjct: 2339 AGPAC-DKVLPEWAFGRDSWIHYEPRNTLSTLSTRIQLMVRTRISRSTLLSLASADGSSF 2397 Query: 1401 ----------LLHYSYNGETMYLPMATL--SDGAWHRIEIKWLGTDISVTVDY--GLRTV 1446 +++S G++ L M TL ++G W + ++ + ++ V+ G + V Sbjct: 2398 IRLEVDEGYFCVNFSLGGKSHSLRMKTLRINNGQWVLLTMERYNNEFTLRVNSGGGDQEV 2457 Query: 1447 LMPMLANKIQGQYIGKILIGGLDTTAGLLASDVGFFEGCIQDVRIGTAQSLL--NRPTV- 1503 + ++ +++G L + F+GC++DV++ Q LL R T Sbjct: 2458 TSVLGTDRWFEMDWASVVLGN-----RLPSHSESDFQGCLRDVQL-NGQPLLVEGRSTEF 2511 Query: 1504 -----RENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRV----GPQCVSACEL 1554 R+ V GC S A C C CV W C C AG+V + C Sbjct: 2512 GFVLRRQGVTMGCHSSA-CSSHPCYSPFLCVDLWRKYECRCPAGKVEVTDNLTGLRHCSS 2570 Query: 1555 GPCGAARCVPDQTPKGYS-----CACEPGY 1579 PCG C T S C C GY Sbjct: 2571 SPCGHWTCRNGGTCVAQSQHKTICQCPEGY 2600 Score = 315 bits (774), Expect = 1e-83 Identities = 262/849 (30%), Positives = 411/849 (48%), Gaps = 82/849 (9%) Query: 10 QINVL--DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 QI VL D ND+ P FE +Y+ + E GT+ L + A D D G NA + Y++ Sbjct: 816 QITVLIADVNDNDPKFENSRYQYFLSEDTPIGTSFLRVTAHDSDQGVNAAITYSM----- 870 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 VQ F+I+ +G + + + R + + ATD Sbjct: 871 --------------LAHQVQ-YFQINPSTGWVYVNHRI--SQTTRISHYIVATD-----G 908 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 SST + V I + P++ + Y V+V E+ ++ D ++ IKAT + +G + + Sbjct: 909 GNRSSTVELTVTITNALSQPPRWEQSRYWVTVPEN-TIRDTRIVT-IKAT-SPLG-DPRV 964 Query: 188 RYAIIGG-----NTQMQFSI--DSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRS 238 Y + G N ++F + + G SL+ + LD+E + + L +RAQ+ + Sbjct: 965 TYNLEEGQVPETNMPIRFYLRPNRADGSASLLVAEPLDFETTKFFSLTVRAQNVAMIPLA 1024 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 + T + +N+ DVNDN P F +S ++ SV E +G S+V+V A D D G++ ++ Y + Sbjct: 1025 SFTIVYVNVTDVNDNVPFFVSSNYEVSVPEGADVGTSVVQVLATDLDSGLHGQVRYFIL- 1083 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP--------PRSATA 350 KD + + TI+P +G + T DRE +A Y + V + D + P + TA Sbjct: 1084 KDASEDYQF-FTIEPETGIISTHASFDREKRASYLIEVQSQDSSESARPGVHGHPNTDTA 1142 Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNT 408 F YEV + ED G+PVVT TA D DE + +L Y+IT GNT Sbjct: 1143 YVRIFVSDVNDNAPAFPQPVYEVSVDEDRDVGSPVVTATADDRDEGANAKLRYQITSGNT 1202 Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468 +G F + + G + + Q LD+++E+RY L + A+D + T ++ IN+ + N+ APV Sbjct: 1203 KGVFDVEPE--AGTVFIVQSLDYEEEQRYELRLVASDGKWENHTLII-INVVNKNDEAPV 1259 Query: 469 FENAPYTASVFED-APIGTTVLVVSATDSDVGINAQ-ITYSLSSEISNEAVAHHDQQFVI 526 F Y S+ E+ + VL VSATD D + ++YSL + + +F I Sbjct: 1260 FTQNEYHGSILEELTDLPVFVLKVSATDPDQEADQNALSYSLHGQGAG-------SEFSI 1312 Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF---KQ 583 N TG I+ N+ LDRE S + V A D L+ DV I V D NDN P+F Sbjct: 1313 NENTGEISANRRLDREKRSTWRFLVLATDESGEGLTGFADVVIEVRDTNDNAPLFLCVSD 1372 Query: 584 QLYTANIMEDALVGTSVSQVGATDAD---VGLNGRIHYELDPKDREE---GSFVIDPASG 637 + + ED+ T+V ++ A D D + + Y + + E F I+P SG Sbjct: 1373 DCFMGYVPEDSPADTAVMEMTAVDLDDPKASTHAVLTYRIIQNVQNEINLNLFSINPVSG 1432 Query: 638 VIRT-NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696 I T +LDRE V + L A DGG + T I + D+ND PVF T ++ Sbjct: 1433 TICTVLGSLDREKVDKYLLVVEARDGGGLTGTGTAT--ILVTDVNDHAPVFLQRIYTAFV 1490 Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756 SEN+ I T + + A D DEG NA+V +SI GD+ FS+ET +G++ + +D+ Sbjct: 1491 SENASINTEVAVVSAMDRDEGENAMVTFSILDGDNDCKFSIETDKGNNCGFIHLRKQIDF 1550 Query: 757 ESPRKK-YELVIRAASPPLWNDVRVEILVTDVNDNAPVM-KDFQIIFNNYKDCFPVG-PF 813 E P ++ + L ++A ++ I V D ND+APV F + + +D PVG Sbjct: 1551 EKPHERVFNLTLKAEDMDFFSIAHCVIYVEDANDHAPVFYPQFYEVASLAED-VPVGTKV 1609 Query: 814 GRVPAYDAD 822 +V A D D Sbjct: 1610 VQVSAVDLD 1618 Score = 289 bits (709), Expect = 7e-76 Identities = 253/895 (28%), Positives = 409/895 (45%), Gaps = 80/895 (8%) Query: 11 INVLDCNDHSPVFEMQQYEA-SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +++ D ND SP F+ Y ++ E GT++L + ATD D G N+E+ Y I+ + D Sbjct: 501 VHITDENDCSPEFQNSIYSRDNIPETIPIGTSLLQVLATDCDSGSNSEISYFIQ--STD- 557 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSD 128 F I R G + + L+ E+ Y +V A D+ P Sbjct: 558 --------------------FSIT-RHGVISSNQRLNFERANHMYEFVVIAVDKGHPPR- 595 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 + TA++ + + + ND P FS+ Y + ED + ++A ++A D D + Sbjct: 596 --TGTASVRIQMANVNDEAPVFSQPVYRTFLSEDAG--PSTLVATVRAKDPD---GDGVL 648 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQD----GGSPSRSNTTQL 243 Y I GGN + F +DS G + L ++ + Y L I A D GG S+ ++ Sbjct: 649 YLIAGGNEEGNFELDSQKGIIKLRRSPAPNLKGPQYILNITAIDDNVSGGPTPLSSFAEV 708 Query: 244 LINIRDVNDNAPRFYTSLFQES---VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 ++ + D+N+N P F + V EN P G +++V+AYDAD GVN E+ Y + +D Sbjct: 709 IVGVNDINNNKPVFRECTYYSDSTWVLENQPPGTYVLQVEAYDADLGVNGEVKYGLMHRD 768 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 L +ID +G + T+ DRE Q ++ L VTATD P Sbjct: 769 ---GASLGFSIDSDTGVITTTRSFDREEQKEHTLSVTATDQAPEPLIGICQITVLIADVN 825 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQN 418 F +Y+ L+ED P GT + +TA D+D+ + + Y + + F I Sbjct: 826 DNDPKFENSRYQYFLSEDTPIGTSFLRVTAHDSDQGVNAAITYSMLAHQVQ-YFQINPST 884 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASV 478 G + Q R + ATD G RS T + + IT+A + P +E + Y +V Sbjct: 885 GWVYVNHR----ISQTTRISHYIVATDGGNRSSTVELTVTITNALSQPPRWEQSRYWVTV 940 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ----TGAIT 534 E+ T ++ + AT S +G + ++TY+L E + +F + P + ++ Sbjct: 941 PENTIRDTRIVTIKAT-SPLG-DPRVTYNL--EEGQVPETNMPIRFYLRPNRADGSASLL 996 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 + LD ET + LTV A++ + L+ T V ++V DVNDN P F Y ++ E A Sbjct: 997 VAEPLDFETTKFFSLTVRAQNVAMIPLASFTIVYVNVTDVNDNVPFFVSSNYEVSVPEGA 1056 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEG--SFVIDPASGVIRTNKALDRESVAT 652 VGTSV QV ATD D GL+G++ Y + KD E F I+P +G+I T+ + DRE A+ Sbjct: 1057 DVGTSVVQVLATDLDSGLHGQVRYFI-LKDASEDYQFFTIEPETGIISTHASFDREKRAS 1115 Query: 653 HDLKAVAIDGGTP--------PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 + ++ + D P + T V I + D+ND+ P F + E+ +G+ Sbjct: 1116 YLIEVQSQDSSESARPGVHGHPNTDTAYVRIFVSDVNDNAPAFPQPVYEVSVDEDRDVGS 1175 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764 + A D DEG NA + Y I G+ F +E G+ + + LDYE ++YE Sbjct: 1176 PVVTATADDRDEGANAKLRYQITSGNTKGVFDVEPEAGT----VFIVQSLDYEE-EQRYE 1230 Query: 765 LVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADV 823 L + A+ N + I V + ND APV + + ++ + F +V A D D Sbjct: 1231 LRLVASDGKWENHTLIIINVVNKNDEAPVFTQNEYHGSILEELTDLPVFVLKVSATDPDQ 1290 Query: 824 ---TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE 875 + L Y + + +NE TG ++ + +L+ V TD E Sbjct: 1291 EADQNALSYSLHGQGAGSEFSINENTGEISANRRLDREKRSTWRFLVLATDESGE 1345 Score = 264 bits (648), Expect = 2e-68 Identities = 237/812 (29%), Positives = 385/812 (47%), Gaps = 82/812 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I V D ND++P F YE SV E G+ V+T A D+D G NA++ Y ++ + +T Sbjct: 1145 RIFVSDVNDNAPAFPQPVYEVSVDEDRDVGSPVVTATADDRDEGANAKLRY--QITSGNT 1202 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + VF ++ +G + SLD E+ RY + + A+D + Sbjct: 1203 -----------------KGVFDVEPEAGTVFIVQSLDYEEEQRYELRLVASD------GK 1239 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV-IAKIKATDADVGAN-SAI 187 + I +N+++ ND P F++ Y S+ E++ TD PV + K+ ATD D A+ +A+ Sbjct: 1240 WENHTLIIINVVNKNDEAPVFTQNEYHGSILEEL--TDLPVFVLKVSATDPDQEADQNAL 1297 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 Y++ G +FSI+ +G++S + LD E+ ++R ++ A D + ++I + Sbjct: 1298 SYSLHGQGAGSEFSINENTGEISANRRLDREKRSTWRFLVLATDESGEGLTGFADVVIEV 1357 Query: 248 RDVNDNAPRFY---TSLFQESVSENVPIGYSIVRVQAYDADE---GVNAELTYTMTDKDY 301 RD NDNAP F F V E+ P +++ + A D D+ +A LTY + ++ Sbjct: 1358 RDTNDNAPLFLCVSDDCFMGYVPEDSPADTAVMEMTAVDLDDPKASTHAVLTYRII-QNV 1416 Query: 302 TGNVDLPI-TIDPRSGWVYT-SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 ++L + +I+P SG + T G LDRE KY L+V A DGG + T T Sbjct: 1417 QNEINLNLFSINPVSGTICTVLGSLDREKVDKYLLVVEARDGGG--LTGTGTATILVTDV 1474 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQ 417 F+ Y ++E+ T V ++A D DE + + I G+ +FSI + Sbjct: 1475 NDHAPVFLQRIYTAFVSENASINTEVAVVSAMDRDEGENAMVTFSILDGDNDCKFSIETD 1534 Query: 418 NGR--GLITVAQPLDFKQ--ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAP 473 G G I + + +DF++ ER + LT+ A D S A I + DAN++APVF Sbjct: 1535 KGNNCGFIHLRKQIDFEKPHERVFNLTLKAEDMDFFS-IAHCVIYVEDANDHAPVFYPQF 1593 Query: 474 Y-TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 Y AS+ ED P+GT V+ VSA D D G+N + ++ L ++ + QF + G Sbjct: 1594 YEVASLAEDVPVGTKVVQVSAVDLDSGLNGRFSFHLLNK------SDPGGQFSV-ASDGW 1646 Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592 + +LD ET++ Y L V A D G P L+ + V +++ DVNDN P F+ Y + E Sbjct: 1647 VIVAGVLDHETVTQYQLIVIATDMGQPPLACSATVLVTLQDVNDNGPEFEAH-YNPVVWE 1705 Query: 593 DALVGTSVSQ------VGATDADVGLNGR-IHYELDPKDREEGSFVIDP---ASGVIRTN 642 + SV + A D D NG + L G+F + S ++ Sbjct: 1706 NTASPQSVQMNETSTLLYAKDRDTAANGAPFSFHLLSNFDSLGNFHLQDFHNGSALLTAL 1765 Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP-PVFESDCLTFYISENSP 701 DRE L + D G PP SST + + I D ND P +CL + P Sbjct: 1766 HTFDREVHKVFHLPILITDSGIPPMSSTNTLTVNIGDQNDHPHSAGYMECLIYSYDGILP 1825 Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761 T +G++ A D D+ + + G S F L +D + L+T+ + +P Sbjct: 1826 T-TVLGQVLAPDGDDWDRKIYQFE---GKTSRYFIL-----NDNSGLLTIKE---GTPPG 1873 Query: 762 KYELVIRAASPPLWNDV--RVEILVTDVNDNA 791 Y + +R +W DV V+++V ++ D+A Sbjct: 1874 TYNIKVRVID-GVWPDVVSTVKVIVKEIKDDA 1904 Score = 243 bits (594), Expect = 6e-62 Identities = 239/817 (29%), Positives = 368/817 (45%), Gaps = 80/817 (9%) Query: 11 INVLDCNDHSPVF-EMQQYEAS--VREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 + V D N++ PVF E Y S V E GT VL ++A D D+G N EV+Y + Sbjct: 710 VGVNDINNNKPVFRECTYYSDSTWVLENQPPGTYVLQVEAYDADLGVNGEVKYGL----- 764 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 ++ + A F ID +G + T S DRE+ +T+ V ATDQA Sbjct: 765 --MHRDGASLG-----------FSIDSDTGVITTTRSFDREEQKEHTLSVTATDQA---P 808 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 + L I V I D NDN P+F Y + ED + + ++ A D+D G N+AI Sbjct: 809 EPLIGICQITVLIADVNDNDPKFENSRYQYFLSEDTPIGTS--FLRVTAHDSDQGVNAAI 866 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 Y+++ Q F I+ +G V + + S+ +V A DGG +RS+T +L + I Sbjct: 867 TYSMLAHQVQ-YFQINPSTGWVYVNHRISQTTRISHYIV--ATDGG--NRSSTVELTVTI 921 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 + PR+ S + +V EN IV ++A + G + +TY + ++ ++ Sbjct: 922 TNALSQPPRWEQSRYWVTVPENTIRDTRIVTIKA-TSPLG-DPRVTYNL-EEGQVPETNM 978 Query: 308 PITIDPR------SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 PI R S + + LD ET + L V A + P ++ Sbjct: 979 PIRFYLRPNRADGSASLLVAEPLDFETTKFFSLTVRAQNVAMIPLASFTIVYVNVTDVND 1038 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNG 419 F+ YEV + E GT VV + ATD D ++ Y I + T + Sbjct: 1039 NVPFFVSSNYEVSVPEGADVGTSVVQVLATDLDSGLHGQVRYFILKDASEDYQFFTIEPE 1098 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG----------GRSDTAMVQINITDANNYAPVF 469 G+I+ D ++ Y++ V + DS +DTA V+I ++D N+ AP F Sbjct: 1099 TGIISTHASFDREKRASYLIEVQSQDSSESARPGVHGHPNTDTAYVRIFVSDVNDNAPAF 1158 Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 Y SV ED +G+ V+ +A D D G NA++ Y ++S + + V F + P+ Sbjct: 1159 PQPVYEVSVDEDRDVGSPVVTATADDRDEGANAKLRYQITSG-NTKGV------FDVEPE 1211 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589 G + + LD E Y L + A DG + T + I+VV+ ND PVF Q Y + Sbjct: 1212 AGTVFIVQSLDYEEEQRYELRLVASDG---KWENHTLIIINVVNKNDEAPVFTQNEYHGS 1268 Query: 590 IMEDAL-VGTSVSQVGATDADVGLN-GRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647 I+E+ + V +V ATD D + + Y L + F I+ +G I N+ LDR Sbjct: 1269 ILEELTDLPVFVLKVSATDPDQEADQNALSYSLHGQG-AGSEFSINENTGEISANRRLDR 1327 Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF---ESDCLTFYISENSPIGT 704 E +T +A D + V I++ D ND+ P+F DC Y+ E+SP T Sbjct: 1328 EKRSTWRFLVLATDESGEGLTGFADVVIEVRDTNDNAPLFLCVSDDCFMGYVPEDSPADT 1387 Query: 705 TIGEIRA---HDPDEGPNAVVHY----SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757 + E+ A DP +AV+ Y +++ + N FS+ G+ + LD E Sbjct: 1388 AVMEMTAVDLDDPKASTHAVLTYRIIQNVQNEINLNLFSINPVSGT---ICTVLGSLDRE 1444 Query: 758 SPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAPV 793 KY LV+ A L ILVTDVND+APV Sbjct: 1445 KV-DKYLLVVEARDGGGLTGTGTATILVTDVNDHAPV 1480 Score = 237 bits (581), Expect = 2e-60 Identities = 233/837 (27%), Positives = 382/837 (45%), Gaps = 82/837 (9%) Query: 89 VFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 +F + SG LL +D E Y +L+KA + S LSS A + V+I D+ND Sbjct: 455 LFTVRQESGELLLTHPVDYEGEHHLYHLLLKAVEAESA----LSSVAEVMVHITDENDCS 510 Query: 148 PQFSEKTYT-VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206 P+F Y+ ++ E I + + + ++ ATD D G+NS I Y I FSI + Sbjct: 511 PEFQNSIYSRDNIPETIPIGTS--LLQVLATDCDSGSNSEISYFI----QSTDFSI-TRH 563 Query: 207 GDVSLVKTLDYEQV-RSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265 G +S + L++E+ Y V+ A D G P R+ T + I + +VND AP F +++ Sbjct: 564 GVISSNQRLNFERANHMYEFVVIAVDKGHPPRTGTASVRIQMANVNDEAPVFSQPVYRTF 623 Query: 266 VSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV-YTSGQ 323 +SE+ + V+A D D +GV Y + + GN +L D + G + Sbjct: 624 LSEDAGPSTLVATVRAKDPDGDGV----LYLIAGGNEEGNFEL----DSQKGIIKLRRSP 675 Query: 324 LDRETQAKYQLLVTATD----GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE---LA 376 +Y L +TA D GG P S+ A F Y + + Sbjct: 676 APNLKGPQYILNITAIDDNVSGGPTPLSSFAEVIVGVNDINNNKPVFRECTYYSDSTWVL 735 Query: 377 EDEPPGTPVVTLTATDAD--EDNRLHYEI--TGGNTRGRFSITSQNGRGLITVAQPLDFK 432 E++PPGT V+ + A DAD + + Y + G + G FSI S G+IT + D + Sbjct: 736 ENQPPGTYVLQVEAYDADLGVNGEVKYGLMHRDGASLG-FSIDSDT--GVITTTRSFDRE 792 Query: 433 QERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 +++ + L+V+ATD + QI I D N+ P FEN+ Y + ED PIGT+ L Sbjct: 793 EQKEHTLSVTATDQAPEPLIGICQITVLIADVNDNDPKFENSRYQYFLSEDTPIGTSFLR 852 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550 V+A DSD G+NA ITYS+ +AH Q F INP TG + N + + T + + Sbjct: 853 VTAHDSDQGVNAAITYSM--------LAHQVQYFQINPSTGWVYVNHRISQTTRISHYIV 904 Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610 T DGG + S T ++ +++ + P ++Q Y + E+ + T + + AT + + Sbjct: 905 AT--DGG--NRSSTVELTVTITNALSQPPRWEQSRYWVTVPENTIRDTRIVTIKAT-SPL 959 Query: 611 GLNGRIHYELD----PKDREEGSFVIDP----ASGVIRTNKALDRESVATHDLKAVAIDG 662 G + R+ Y L+ P+ F + P S + + LD E+ L A + Sbjct: 960 G-DPRVTYNLEEGQVPETNMPIRFYLRPNRADGSASLLVAEPLDFETTKFFSLTVRAQNV 1018 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 P +S IV++ + D+ND+ P F S + E + +GT++ ++ A D D G + V Sbjct: 1019 AMIPLASFTIVYVNVTDVNDNVPFFVSSNYEVSVPEGADVGTSVVQVLATDLDSGLHGQV 1078 Query: 723 HYSI--KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR------AASP-- 772 Y I +D F++E G + T D E R Y + ++ +A P Sbjct: 1079 RYFILKDASEDYQFFTIEPETGI----ISTHASFDREK-RASYLIEVQSQDSSESARPGV 1133 Query: 773 ---PLWNDVRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPAYDADVTDKL 827 P + V I V+DVNDNAP +++ + +D D KL Sbjct: 1134 HGHPNTDTAYVRIFVSDVNDNAPAFPQPVYEVSVDEDRDVGSPVVTATADDRDEGANAKL 1193 Query: 828 QYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884 +Y+I SGN + + G++ + L+ + + + +DG E ++ ++V Sbjct: 1194 RYQITSGNTKGVFDVEPEAGTVFIVQSLDYEEEQRYELRLVASDGKWENHTLIIINV 1250 Score = 185 bits (450), Expect = 2e-44 Identities = 169/606 (27%), Positives = 276/606 (45%), Gaps = 48/606 (7%) Query: 137 HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA-IRYAIIGGN 195 HV ++ + ++ Y D ++ ++ A ++ SA + Y +I G Sbjct: 297 HVTLLAPEEELLSWAMYPYPYLARVDPDARKGTLVYRLAARYSNSENTSAGVSYTLIAGG 356 Query: 196 TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG-GSPSRSNTTQLLINIRDVNDNA 254 + +F +D +G + + L + Y + ++A D G+ S + +L+ R Sbjct: 357 EE-RFQVDVDTG-IIVTTGLPLVWNKEYVVTVQASDEYGNKSPFASISILVGSRP----- 409 Query: 255 PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR 314 P+F + V EN P G + V+A + L+Y++ N T+ Sbjct: 410 PQFTNMSYSVFVPENTPPGEKVAVVEAVSFQ---SQPLSYSLLT-----NPSGLFTVRQE 461 Query: 315 SGWVYTSGQLDRETQAK-YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373 SG + + +D E + Y LL+ A + + S+ A F Y Sbjct: 462 SGELLLTHPVDYEGEHHLYHLLLKAVEA-ESALSSVAEVMVHITDENDCSPEFQNSIYSR 520 Query: 374 E-LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432 + + E P GT ++ + ATD D + + EI+ FSIT G+I+ Q L+F+ Sbjct: 521 DNIPETIPIGTSLLQVLATDCDSGS--NSEISYFIQSTDFSITRH---GVISSNQRLNFE 575 Query: 433 QERR-YVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 + Y V A D G R+ TA V+I + + N+ APVF Y + EDA T V Sbjct: 576 RANHMYEFVVIAVDKGHPPRTGTASVRIQMANVNDEAPVFSQPVYRTFLSEDAGPSTLVA 635 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG--Y 547 V A D D + Y ++ NE + F ++ Q G I + + G Y Sbjct: 636 TVRAKDPD---GDGVLYLIAG--GNE-----EGNFELDSQKGIIKLRRS-PAPNLKGPQY 684 Query: 548 LLTVTARD----GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN---IMEDALVGTSV 600 +L +TA D GG LS +V + V D+N+N+PVF++ Y ++ ++E+ GT V Sbjct: 685 ILNITAIDDNVSGGPTPLSSFAEVIVGVNDINNNKPVFRECTYYSDSTWVLENQPPGTYV 744 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 QV A DAD+G+NG + Y L +D F ID +GVI T ++ DRE H L A Sbjct: 745 LQVEAYDADLGVNGEVKYGLMHRDGASLGFSIDSDTGVITTTRSFDREEQKEHTLSVTAT 804 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 D P + + I D+ND+ P FE+ +++SE++PIGT+ + AHD D+G NA Sbjct: 805 DQAPEPLIGICQITVLIADVNDNDPKFENSRYQYFLSEDTPIGTSFLRVTAHDSDQGVNA 864 Query: 721 VVHYSI 726 + YS+ Sbjct: 865 AITYSM 870 Score = 83.8 bits (198), Expect = 6e-14 Identities = 113/411 (27%), Positives = 174/411 (42%), Gaps = 39/411 (9%) Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 PY A V DA GT V ++A S N++ T S+ +S +A +++F ++ TG Sbjct: 316 PYLARVDPDARKGTLVYRLAARYS----NSENT---SAGVSYTLIAGGEERFQVDVDTGI 368 Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592 I T L Y++TV A D + + IS++ V P F Y+ + E Sbjct: 369 IVTTGL-PLVWNKEYVVTVQASD---EYGNKSPFASISIL-VGSRPPQFTNMSYSVFVPE 423 Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA- 651 + G V+ V A + + Y L G F + SG + +D E Sbjct: 424 NTPPGEKVAVVEAVSFQ---SQPLSYSL--LTNPSGLFTVRQESGELLLTHPVDYEGEHH 478 Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF-YISENSPIGTTIGEIR 710 + L A++ + SS V + I D ND P F++ + I E PIGT++ ++ Sbjct: 479 LYHLLLKAVEAESA-LSSVAEVMVHITDENDCSPEFQNSIYSRDNIPETIPIGTSLLQVL 537 Query: 711 AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770 A D D G N+ + Y I+ S FS+ TR G + + L++E YE V+ A Sbjct: 538 ATDCDSGSNSEISYFIQ----STDFSI-TRHG----VISSNQRLNFERANHMYEFVVIAV 588 Query: 771 S---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY--KDCFPVGPFGRVPAYDADVTD 825 PP V I + +VND APV Q ++ + +D P V A D D D Sbjct: 589 DKGHPPRTGTASVRIQMANVNDEAPVFS--QPVYRTFLSEDAGPSTLVATVRAKDPD-GD 645 Query: 826 KLQYRILSGNNANLILLNETTGSMTL--SPQLNTNVPKLATMEVSVTDGVN 874 + Y I GN L+ G + L SP N P+ ++ D V+ Sbjct: 646 GVLYLIAGGNEEGNFELDSQKGIIKLRRSPAPNLKGPQYILNITAIDDNVS 696 Score = 83.8 bits (198), Expect = 6e-14 Identities = 82/257 (31%), Positives = 114/257 (44%), Gaps = 35/257 (13%) Query: 8 HQQINVLDCNDHSPVFEMQQYE-ASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 H I V D NDH+PVF Q YE AS+ E GT V+ + A D D G N + + Sbjct: 1574 HCVIYVEDANDHAPVFYPQFYEVASLAEDVPVGTKVVQVSAVDLDSGLNGRFSFHL---- 1629 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 LN D F + G ++ LD E V +Y ++V ATD P Sbjct: 1630 ---LNKSDPGGQ-----------FSV-ASDGWVIVAGVLDHETVTQYQLIVIATDMGQP- 1673 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI----SVTDNPVIAKIKATDADVG 182 L+ +AT+ V + D NDN P+F E Y V E+ SV N + A D D Sbjct: 1674 --PLACSATVLVTLQDVNDNGPEF-EAHYNPVVWENTASPQSVQMNETSTLLYAKDRDTA 1730 Query: 183 ANSA-IRYAIIG-----GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS 236 AN A + ++ GN +Q + S ++ + T D E + + L I D G P Sbjct: 1731 ANGAPFSFHLLSNFDSLGNFHLQ-DFHNGSALLTALHTFDREVHKVFHLPILITDSGIPP 1789 Query: 237 RSNTTQLLINIRDVNDN 253 S+T L +NI D ND+ Sbjct: 1790 MSSTNTLTVNIGDQNDH 1806 Score = 42.3 bits (95), Expect = 0.19 Identities = 31/94 (32%), Positives = 46/94 (48%), Gaps = 5/94 (5%) Query: 695 YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV--TMV 752 ++ E+SP GT + +R P GP GD ++ FSL+ R G ++ L T Sbjct: 32 HVPEDSPAGTRVRGVRV--PLRGPGEPPARWALRGDGAHHFSLQRRPGGERGALEARTAR 89 Query: 753 DLDYESPRKKYELVIRAASPPLWNDVRVEILVTD 786 LD R +Y L++RAA P +RV +L D Sbjct: 90 RLD-RGARAEYRLLLRAAVRPRAALLRVRVLARD 122 >UniRef50_UPI00015B6261 Cluster: PREDICTED: similar to CG7749-PA; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to CG7749-PA - Nasonia vitripennis Length = 4840 Score = 462 bits (1139), Expect = e-128 Identities = 400/1400 (28%), Positives = 640/1400 (45%), Gaps = 131/1400 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD NDH+P FE Y +V E GT++L + A D D+G N EV Y+ + Sbjct: 2889 LQVLDENDHAPKFESNPYSIAVAENIEEGTSILKVVAHDNDLGSNGEVRYSFGSDIGELA 2948 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N VF ID +G + + LD+E+ Y V ATD +P R Sbjct: 2949 N-----------------VFTIDAYTGWISSLVQLDKEQQPEYKFQVIATDNGNP---RH 2988 Query: 131 SSTATIHVNIIDDNDNYPQFS--EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 S ++ V + D NDN FS E Y +V ED V+ ++ D D N+A+ Sbjct: 2989 FSRTSVLVKLKDYNDNPSAFSSAESGYQATVKED--ALPGTVVVELTTVDKDTELNTALD 3046 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 + II G+ + QF+I S +G V + K LD E Y L++ DG T++++ + Sbjct: 3047 FYIISGDPRSQFAIRS-TGQVYVAKALDRETRDRYELLVVGTDGKFVFE---TRVIVQVL 3102 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 DVNDN P ++E +SE G ++ V A D D+ NA+L + +T G + Sbjct: 3103 DVNDNPPYCLKYRYREVLSEGSHPGSYVLTVLATDYDDEPNAKLRFYLT-----GGKNEK 3157 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 ++D +G + T GQLDRE+QAKY L D ++ F Sbjct: 3158 FSLDKETGVLKTVGQLDRESQAKYILTAHVQDRDKTSWECSSQLEILISDLNDNAPRFSM 3217 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 Y L ED GT V + ATD D + ++ YE + F I+ +G ++T+A Sbjct: 3218 QSYSATLPEDVEVGTLVTKVHATDDDIGINRKIRYEFLD-SANDHFVISPDSG--IVTLA 3274 Query: 427 QPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 +PLD + + Y +++ A D G S + +N+ D N+ P F + Y A V E + Sbjct: 3275 KPLDRETKAMYNVSIQAMDQGTPQLSSVTFLIVNVQDINDNPPEFTSKYYFARVPEIDAV 3334 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 GT V V AT D G+NA + Y++ NE ++F I+ ++G ++ + LD E Sbjct: 3335 GTEVARVLATSKDTGVNADVYYTIVG--GNE-----HKKFEIDTKSGVVSIAEQLDYERA 3387 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 Y LT+ A DGGVP L++ V I+V+D NDN P+F Q Y A+I EDA G V QV Sbjct: 3388 KDYFLTIQAIDGGVPPLTNHATVNITVLDSNDNAPMFSQASYRASIREDAKAGEKVVQVF 3447 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 A D D NG++ Y ++ DR++ F ID SG I LDRE +A++ L+ A D G Sbjct: 3448 ANDLDSNENGQVSYSIERGDRQK-QFTIDSQSGQITVLAPLDREQIASYVLEVHAKDNGI 3506 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH- 723 P S+ VIV+I++ D ND+PP+F + T + E+ P+G + + D D PNA + Sbjct: 3507 PTLSNYVIVNIEVIDANDNPPLFAQNNYTTVVQEDKPLGYAVLKFTVTDADAEPNAAPYT 3566 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRV 780 + + G++ ++F LE + G+ L T + KY L IR SPPL++D V Sbjct: 3567 FDFRSGNEGDAFRLE-QDGT----LRTATKFS-NRVKDKYLLHIRVFDNGSPPLYSDAWV 3620 Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRIL----SGNN 836 + + + + PV+ +I N+Y D +P G G+V A D D D LQY ++ S N Sbjct: 3621 LVKIIEESQYPPVITLLEININSYMDEYPGGVIGKVHASDKDQYDTLQYSLVPTSPSRPN 3680 Query: 837 ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSI 896 +L +++ G++ P+L+ + + VSVTDG +++++V L+T+ ML NS+ Sbjct: 3681 TDLFQIDKLDGTLVALPRLDIGEYR---VNVSVTDGKFNSYTIVKVTVELVTDTMLENSV 3737 Query: 897 TVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILN---VSFSA 953 VR +++ E F+ F+ + + C +++ I SVQ TD N++ V + Sbjct: 3738 IVRFREVSPEDFVLKHRKGFVRTVRNAMNCRLKDVVILSVQPSTDAEINVIKSRPVRQAV 3797 Query: 954 RRPDAEVGVA---GDPSPHYSPTHLRERVYLHRTTL---ARLATVQVLPF--DDNICVHE 1005 D +V DP Y+ +RE + H L +L +++ F CV+ Sbjct: 3798 VHNDLDVLFTVKKPDPGEFYTSEAIREALNQHIEELEASTKLVVEEIVRFKCSKGYCVYG 3857 Query: 1006 PCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKAS-- 1063 C + VL + + P + + C C EG+ G +CE ++ + + Sbjct: 3858 ECHD----KIVLDSQQITPIATDVTSFVSPRHRHRT-ECSCKEGYAGTHCEIVINECARG 3912 Query: 1064 -CEV----DGDGSICRSGSQCVARREGGILCQGCSIDAAYT-TAVCELRAR--SFPVSSF 1115 C V D S+ QC G Q C ID + C + SF S+ Sbjct: 3913 PCPVFKVCIPDSSVQGYSCQC----PEGFAGQTCDIDISKCHDESCYIPRNPISFSGKSY 3968 Query: 1116 LTF---PGLKRR---HRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRGGG 1169 + L R+ +++ L L+ + +G L+Y + D+ LE+V+ Sbjct: 3969 ARYKIDKSLVRQTIENQLSLSLRIRSVQPTGNLMYAA---GKVDYNVLEIVNG------- 4018 Query: 1170 PGLRFSFSLGGGKSEITVEG-NVGDGSWHTVEIEYFNRTITMILDDCDKVLSLAGAADFG 1228 +++ F LG G+ + V + DG WH +++E + + T+ +D K L+ A Sbjct: 4019 -AVQYRFDLGSGEGLVRVNSFYISDGQWHEIQLERESNSATLTVD--GKHLAHGSAPGVN 4075 Query: 1229 LKYACANFTRKVLPARCEIPTE-TCHRFLDLTGPLQIGGLPNIPSSFQVKNKDFVGCISD 1287 N L E+ + + F D+ +G + ++ + G S Sbjct: 4076 ---DILNLQSDDLYLGAEVRSHPSIIGFEDVQRGF-VGCMDDVRIAKVSVPLHMSGSTSS 4131 Query: 1288 FYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDT---YICDCKEGHT 1344 + +F ++ + + T+ P C S PC NG CS+ Y C C Sbjct: 4132 LVVLKRFANV-EFSCEASTVLTPP---GVCGSQPCQNGGTCSESKTEDGGYECQCHNRFR 4187 Query: 1345 GKDCADSTGP----PWRFGG 1360 G C T P P +GG Sbjct: 4188 GASCEIDTDPCASSPCLYGG 4207 Score = 364 bits (896), Expect = 2e-98 Identities = 265/890 (29%), Positives = 436/890 (48%), Gaps = 59/890 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ V D ND+SPVF +++Y+AS+ + + L +KA D D G A++ Y+I Sbjct: 2678 RVKVTDENDNSPVFLLKEYKASIYGNLTLNSAFLKVKALDADEGDAAKIIYSI------- 2730 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 P+++ ++++F I+ +GA+ + S + + + V+A D+ S Sbjct: 2731 FEPQNSE---------IKNIFGINPDTGAVFLKKSAKPWETQPFQLFVRAQDKGL-ASHH 2780 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + + + I+ D P F K V E S P+ T+ NS + Sbjct: 2781 VD--VPVEIYIMGPEDIPPLFERKEDKFFVSET-STIGTPITRLRTVTNT----NSTVTC 2833 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 ++ F++D + V+L LD E SY + + A+ SP + ++ + + D Sbjct: 2834 RLVSAGDDFPFAVDPKTCRVTLSGNLDREVKDSYMIGVLAETDSSPPLTALAEITLQVLD 2893 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM-TDKDYTGNVDLP 308 ND+AP+F ++ + +V+EN+ G SI++V A+D D G N E+ Y+ +D NV Sbjct: 2894 ENDHAPKFESNPYSIAVAENIEEGTSILKVVAHDNDLGSNGEVRYSFGSDIGELANV--- 2950 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 TID +GW+ + QLD+E Q +Y+ V ATD G+P + + F Sbjct: 2951 FTIDAYTGWISSLVQLDKEQQPEYKFQVIATDNGNPRHFSRTSVLVKLKDYNDNPSAFSS 3010 Query: 369 GQ--YEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLIT 424 + Y+ + ED PGT VV LT D D + L + I G+ R +F+I S G + Sbjct: 3011 AESGYQATVKEDALPGTVVVELTTVDKDTELNTALDFYIISGDPRSQFAIRST---GQVY 3067 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 VA+ LD + RY L V TD +T ++ + + D N+ P Y + E + Sbjct: 3068 VAKALDRETRDRYELLVVGTDGKFVFETRVI-VQVLDVNDNPPYCLKYRYREVLSEGSHP 3126 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 G+ VL V ATD D NA++ + L+ +++F ++ +TG + T LDRE+ Sbjct: 3127 GSYVLTVLATDYDDEPNAKLRFYLTGG--------KNEKFSLDKETGVLKTVGQLDRESQ 3178 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 + Y+LT +D S ++ +EI + D+NDN P F Q Y+A + ED VGT V++V Sbjct: 3179 AKYILTAHVQDRDKTSWECSSQLEILISDLNDNAPRFSMQSYSATLPEDVEVGTLVTKVH 3238 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 ATD D+G+N +I YE D FVI P SG++ K LDRE+ A +++ A+D GT Sbjct: 3239 ATDDDIGINRKIRYEF--LDSANDHFVISPDSGIVTLAKPLDRETKAMYNVSIQAMDQGT 3296 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 P SS + + ++DIND+PP F S + E +GT + + A D G NA V+Y Sbjct: 3297 PQLSSVTFLIVNVQDINDNPPEFTSKYYFARVPEIDAVGTEVARVLATSKDTGVNADVYY 3356 Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVIRAAS---PPLWNDVRV 780 +I GG++ F ++T+ G +V++ + LDYE K Y L I+A PPL N V Sbjct: 3357 TIVGGNEHKKFEIDTKSG-----VVSIAEQLDYER-AKDYFLTIQAIDGGVPPLTNHATV 3410 Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGNNAN 838 I V D NDNAP+ + +D +V A D D + ++ Y I G+ Sbjct: 3411 NITVLDSNDNAPMFSQASYRASIREDAKAGEKVVQVFANDLDSNENGQVSYSIERGDRQK 3470 Query: 839 LILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLI 887 ++ +G +T+ L+ +EV D G+ + + +++ +I Sbjct: 3471 QFTIDSQSGQITVLAPLDREQIASYVLEVHAKDNGIPTLSNYVIVNIEVI 3520 Score = 311 bits (763), Expect = 2e-82 Identities = 250/881 (28%), Positives = 417/881 (47%), Gaps = 77/881 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +++V D ND++P F + Y VRE + + ++ATD D G +EY+ ++ Sbjct: 1002 RVSVDDVNDNAPKFALTSYTVKVREDVPVWSVIAVIEATDPDEGPGGIIEYSF----SEE 1057 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + E F ID SG + + LD E+ +T+ + A D+ P Sbjct: 1058 MESE--------------GFFGIDKLSGTIRSLQKLDFEERQVHTLTIVAKDKGEP---S 1100 Query: 130 LSSTATIHVNIIDDNDNY--PQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSA 186 LSS + + ++D N+N P F++ + SV E+ + N ++ ++KA DAD G +S Sbjct: 1101 LSSETILIIEVVDVNENLHAPVFNDFVISASVSENQPL--NTLVTQVKAKDADPPGGDSR 1158 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 I Y+I GG+ FSID G++ LD E Y L + AQD G S+ Q+ + Sbjct: 1159 IGYSIRGGDGVGLFSIDD-EGNIRTKAVLDVEAKAGYWLTVYAQDHGVVPLSSKLQVYVE 1217 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + D NDN P ++ SV EN P G S+++++A+D D + ++ +T +GN + Sbjct: 1218 VLDENDNTPLTEQPVYYPSVLENSPAGVSVLQIRAFDRDVSPQ-QFSFAIT----SGNAE 1272 Query: 307 LPITIDPRSGWVYTSG-QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 I+ SG + TSG +LDRE QA++ L VT D G P S+T Sbjct: 1273 GYFLINSTSGLITTSGRKLDRENQAEHILEVTVRDDGRPVLSSTTRVVVQVDDVNDHSPV 1332 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLI 423 F Y V++ P+ + A D D ++ ++ Y I G +G+F I G Sbjct: 1333 FEEKFYMVQIPASPSLDKPLFQVLAHDQDIGKNGKIQYSIKSGKGKGKFKIHPDTG---- 1388 Query: 424 TVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDA---NNYAPVFENAPYTASV 478 V F+ + + + + ATD G RS A + + + + + PVF++ + V Sbjct: 1389 MVYSQRGFEAGQEFEMIIRATDEGEPPRSHQARISVQVVETPKDSPNPPVFKSLNQSVEV 1448 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 E G V ++ ATD D + Y + + + +FVI G + K Sbjct: 1449 TESDKAGFLVALMQATDKD---GDSLWYDIVEGDTRD-------EFVIGRDDGNVLLAKQ 1498 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL-VG 597 LD ET + Y LT++ DG + T + + V+D+ND+ P + +Y I E+ + G Sbjct: 1499 LDWETQNFYNLTISVTDGVNEA---RTSLFVKVIDINDHRPELSESIYHVEISENVVEKG 1555 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEG--SFVIDPASGVIRTNKALDRESVATHDL 655 ++ Q+ A D D + ++ Y L + F +D +G I N+ALDRE++ H L Sbjct: 1556 EAILQLHAQDLDE--DKKLFYSLHNAQSQASLQIFHVDSLTGTITLNEALDRETIQEHIL 1613 Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 + D GTP + + V + + D ND P F S+ + + E SPIGT + ++ A D D Sbjct: 1614 TVMVKDQGTPAKRNFARVLVTVHDHNDHAPTFISEIIQGKVFETSPIGTAVVQVIAIDRD 1673 Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASP 772 G NA + YS+ G+ N FS++ G+ + +DL + +Y L+++A SP Sbjct: 1674 RGENAQLSYSMTSGNVGNVFSIDPDLGT--IRVARELDL---ATASEYILLVKATDHGSP 1728 Query: 773 PLWNDVRVEILVTDVNDNAP---VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQY 829 L N + V ++VT + DNAP V ++ Y++ +G F V +A T LQ+ Sbjct: 1729 ALSNSIPVHVMVT-MADNAPPRFVRSGAELAAEIYEN-EEIGSF--VKHIEARSTSSLQF 1784 Query: 830 RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVT 870 I+SGN +N +TG ++ +L+ K + ++ T Sbjct: 1785 EIVSGNIGEAFFINPSTGVISTQERLDYEDVKFYNLSIAAT 1825 Score = 307 bits (753), Expect = 3e-81 Identities = 236/768 (30%), Positives = 370/768 (48%), Gaps = 54/768 (7%) Query: 143 DNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI 202 +N + P+F + + V+E + V+A++ A D D+G N + Y I G++ F I Sbjct: 789 ENVHAPEFLDFPNEIRVNESAPI--GFVLARLAARDRDLGYNGKLVYGISAGDSDSVFGI 846 Query: 203 DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLF 262 D +G++ L+ LD E+ Y L I D G P +S + L +++ DVNDNAP+F +L Sbjct: 847 DPDTGELRLIGRLDREREDEYFLNITVYDLGKPQKSASRMLAVSVLDVNDNAPKFEKALA 906 Query: 263 QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322 VSE G I R DAD G NA++ Y++ T D +D +G + G Sbjct: 907 SFRVSEAALNGTIIFRANTTDADLGENAQVAYSLV----TDTSD--FRVDRTTGVLTVFG 960 Query: 323 QLDRETQAKYQLLVTATD--GG---------DPPRSATATXXXXXXXXXXXXXXFMPGQY 371 +LDRE Q+ Y+L + ATD GG +P + A F Y Sbjct: 961 KLDRERQSSYELRIRATDKNGGNDKGEPDFDNPALYSEALVRVSVDDVNDNAPKFALTSY 1020 Query: 372 EVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGG-NTRGRFSITSQNGRGLITVAQP 428 V++ ED P + + + ATD DE + Y + + G F I + G I Q Sbjct: 1021 TVKVREDVPVWSVIAVIEATDPDEGPGGIIEYSFSEEMESEGFFGIDKLS--GTIRSLQK 1078 Query: 429 LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANN--YAPVFENAPYTASVFEDAPI 484 LDF++ + + LT+ A D G S ++ I + D N +APVF + +ASV E+ P+ Sbjct: 1079 LDFEERQVHTLTIVAKDKGEPSLSSETILIIEVVDVNENLHAPVFNDFVISASVSENQPL 1138 Query: 485 GTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 T V V A D+D G +++I YS+ + V F I+ + G I T +LD E Sbjct: 1139 NTLVTQVKAKDADPPGGDSRIGYSIR---GGDGVG----LFSIDDE-GNIRTKAVLDVEA 1190 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 +GY LTV A+D GV LS V + V+D NDN P+ +Q +Y +++E++ G SV Q+ Sbjct: 1191 KAGYWLTVYAQDHGVVPLSSKLQVYVEVLDENDNTPLTEQPVYYPSVLENSPAGVSVLQI 1250 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN-KALDRESVATHDLKAVAIDG 662 A D DV + + + EG F+I+ SG+I T+ + LDRE+ A H L+ D Sbjct: 1251 RAFDRDVSPQ-QFSFAI-TSGNAEGYFLINSTSGLITTSGRKLDRENQAEHILEVTVRDD 1308 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 G P SST V ++++D+ND PVFE I + + + ++ AHD D G N + Sbjct: 1309 GRPVLSSTTRVVVQVDDVNDHSPVFEEKFYMVQIPASPSLDKPLFQVLAHDQDIGKNGKI 1368 Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVR 779 YSIK G F + G + +E+ +++E++IRA PP + R Sbjct: 1369 QYSIKSGKGKGKFKIHPDTG------MVYSQRGFEA-GQEFEMIIRATDEGEPPRSHQAR 1421 Query: 780 VEILVTDV---NDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNN 836 + + V + + N PV K + + A D D D L Y I+ G+ Sbjct: 1422 ISVQVVETPKDSPNPPVFKSLNQSVEVTESDKAGFLVALMQATDKD-GDSLWYDIVEGDT 1480 Query: 837 ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884 + ++ G++ L+ QL+ + +SVTDGVNE + + + V Sbjct: 1481 RDEFVIGRDDGNVLLAKQLDWETQNFYNLTISVTDGVNEARTSLFVKV 1528 Score = 293 bits (718), Expect = 6e-77 Identities = 261/886 (29%), Positives = 406/886 (45%), Gaps = 75/886 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 ++VLD ND++P FE V E A +GT + TD D+G+NA+V Y++ T+D Sbjct: 889 VSVLDVNDNAPKFEKALASFRVSEAALNGTIIFRANTTDADLGENAQVAYSLVTDTSD-- 946 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ------AS 124 FR+D +G L LDRE+ + Y + ++ATD+ Sbjct: 947 -------------------FRVDRTTGVLTVFGKLDRERQSSYELRIRATDKNGGNDKGE 987 Query: 125 PVSDR--LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 P D L S A + V++ D NDN P+F+ +YTV V ED+ V VIA I+ATD D G Sbjct: 988 PDFDNPALYSEALVRVSVDDVNDNAPKFALTSYTVKVREDVPVWS--VIAVIEATDPDEG 1045 Query: 183 ANSAIRYAIIGG-NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 I Y+ ++ F ID LSG + ++ LD+E+ + + L I A+D G PS S+ T Sbjct: 1046 PGGIIEYSFSEEMESEGFFGIDKLSGTIRSLQKLDFEERQVHTLTIVAKDKGEPSLSSET 1105 Query: 242 QLLINIRDVNDN--APRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTD 298 L+I + DVN+N AP F + SVSEN P+ + +V+A DAD G ++ + Y++ Sbjct: 1106 ILIIEVVDVNENLHAPVFNDFVISASVSENQPLNTLVTQVKAKDADPPGGDSRIGYSIRG 1165 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358 D G +ID G + T LD E +A Y L V A D G P S+ Sbjct: 1166 GDGVG----LFSIDD-EGNIRTKAVLDVEAKAGYWLTVYAQDHGVVPLSSKLQVYVEVLD 1220 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD-EDNRLHYEITGGNTRGRFSITSQ 417 Y + E+ P G V+ + A D D + + IT GN G F I S Sbjct: 1221 ENDNTPLTEQPVYYPSVLENSPAGVSVLQIRAFDRDVSPQQFSFAITSGNAEGYFLINST 1280 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYT 475 +G + T + LD + + ++L V+ D G S T V + + D N+++PVFE Y Sbjct: 1281 SGL-ITTSGRKLDRENQAEHILEVTVRDDGRPVLSSTTRVVVQVDDVNDHSPVFEEKFYM 1339 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 + + + V A D D+G N +I YS+ S +F I+P TG + + Sbjct: 1340 VQIPASPSLDKPLFQVLAHDQDIGKNGKIQYSIKS-------GKGKGKFKIHPDTGMVYS 1392 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV---NDNEPVFKQQLYTANIME 592 + E + + + A D G P S + + VV+ + N PVFK + + E Sbjct: 1393 QR--GFEAGQEFEMIIRATDEGEPPRSHQARISVQVVETPKDSPNPPVFKSLNQSVEVTE 1450 Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652 G V+ + ATD D + Y++ D + FVI G + K LD E+ Sbjct: 1451 SDKAGFLVALMQATDKD---GDSLWYDIVEGDTRD-EFVIGRDDGNVLLAKQLDWETQNF 1506 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN-SPIGTTIGEIRA 711 ++L DG ++S + +K+ DIND P ISEN G I ++ A Sbjct: 1507 YNLTISVTDGVNEARTS---LFVKVIDINDHRPELSESIYHVEISENVVEKGEAILQLHA 1563 Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKY--ELVIR 768 D DE + + YS+ + SL+ +T+ + LD E+ ++ +V Sbjct: 1564 QDLDE--DKKLFYSLHNA--QSQASLQIFHVDSLTGTITLNEALDRETIQEHILTVMVKD 1619 Query: 769 AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTD-- 825 +P N RV + V D ND+AP +II + P+G +V A D D + Sbjct: 1620 QGTPAKRNFARVLVTVHDHNDHAPTFIS-EIIQGKVFETSPIGTAVVQVIAIDRDRGENA 1678 Query: 826 KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 +L Y + SGN N+ ++ G++ ++ +L+ + V TD Sbjct: 1679 QLSYSMTSGNVGNVFSIDPDLGTIRVARELDLATASEYILLVKATD 1724 Score = 291 bits (714), Expect = 2e-76 Identities = 253/883 (28%), Positives = 418/883 (47%), Gaps = 81/883 (9%) Query: 17 NDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAX 76 N H+P F E V E A G + L A D+D+G N ++ Y I +D+ Sbjct: 790 NVHAPEFLDFPNEIRVNESAPIGFVLARLAARDRDLGYNGKLVYGISAGDSDS------- 842 Query: 77 XXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATI 136 VF ID +G L LDRE+ Y + + D P + S++ + Sbjct: 843 ------------VFGIDPDTGELRLIGRLDREREDEYFLNITVYDLGKP---QKSASRML 887 Query: 137 HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNT 196 V+++D NDN P+F + + V E + + +I + TDAD+G N+ + Y+++ + Sbjct: 888 AVSVLDVNDNAPKFEKALASFRVSE--AALNGTIIFRANTTDADLGENAQVAYSLVTDTS 945 Query: 197 QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD--GG---------SPSRSNTTQLLI 245 F +D +G +++ LD E+ SY L IRA D GG +P+ + + + Sbjct: 946 --DFRVDRTTGVLTVFGKLDRERQSSYELRIRATDKNGGNDKGEPDFDNPALYSEALVRV 1003 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 ++ DVNDNAP+F + + V E+VP+ I ++A D DEG + Y+ +++ + Sbjct: 1004 SVDDVNDNAPKFALTSYTVKVREDVPVWSVIAVIEATDPDEGPGGIIEYSFSEEMESEGF 1063 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 ID SG + + +LD E + + L + A D G+P S+ Sbjct: 1064 ---FGIDKLSGTIRSLQKLDFEERQVHTLTIVAKDKGEPSLSSETILIIEVVDVNENLHA 1120 Query: 366 --FMPGQYEVELAEDEPPGTPVVTLTATDADE---DNRLHYEITGGNTRGRFSITSQNGR 420 F ++E++P T V + A DAD D+R+ Y I GG+ G FSI + Sbjct: 1121 PVFNDFVISASVSENQPLNTLVTQVKAKDADPPGGDSRIGYSIRGGDGVGLFSIDDE--- 1177 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASV 478 G I LD + + Y LTV A D G S V + + D N+ P+ E Y SV Sbjct: 1178 GNIRTKAVLDVEAKAGYWLTVYAQDHGVVPLSSKLQVYVEVLDENDNTPLTEQPVYYPSV 1237 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN-K 537 E++P G +VL + A D DV Q +++++S + + F+IN +G ITT+ + Sbjct: 1238 LENSPAGVSVLQIRAFDRDVS-PQQFSFAITS-------GNAEGYFLINSTSGLITTSGR 1289 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LDRE + ++L VT RD G P LS TT V + V DVND+ PVF+++ Y I + Sbjct: 1290 KLDRENQAEHILEVTVRDDGRPVLSSTTRVVVQVDDVNDHSPVFEEKFYMVQIPASPSLD 1349 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 + QV A D D+G NG+I Y + + +G F I P +G++ + + E+ ++ Sbjct: 1350 KPLFQVLAHDQDIGKNGKIQYSI-KSGKGKGKFKIHPDTGMVYSQRGF--EAGQEFEMII 1406 Query: 658 VAIDGGTPPQSSTVIVHIK-IEDINDS--PPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 A D G PP+S + ++ +E DS PPVF+S + ++E+ G + ++A D Sbjct: 1407 RATDEGEPPRSHQARISVQVVETPKDSPNPPVFKSLNQSVEVTESDKAGFLVALMQATDK 1466 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL 774 D G + + Y I GD + F + G D ++ LD+E+ + Y L I Sbjct: 1467 D-GDS--LWYDIVEGDTRDEFVI----GRDDGNVLLAKQLDWET-QNFYNLTISVTDGV- 1517 Query: 775 WNDVRVEIL--VTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRI 831 N+ R + V D+ND+ P + + ++ G ++ A D D KL Y + Sbjct: 1518 -NEARTSLFVKVIDINDHRPELSESIYHVEISENVVEKGEAILQLHAQDLDEDKKLFYSL 1576 Query: 832 LSG-NNANLIL--LNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + + A+L + ++ TG++TL+ L+ + + V V D Sbjct: 1577 HNAQSQASLQIFHVDSLTGTITLNEALDRETIQEHILTVMVKD 1619 Score = 280 bits (687), Expect = 3e-73 Identities = 254/887 (28%), Positives = 405/887 (45%), Gaps = 69/887 (7%) Query: 21 PVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXX 80 PVF+ V E +G V ++ATD+D + Y ++V DT Sbjct: 1437 PVFKSLNQSVEVTESDKAGFLVALMQATDKD---GDSLWY--DIVEGDT----------- 1480 Query: 81 XXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNI 140 +D F I G +L LD E Y + + TD + + ++ V + Sbjct: 1481 ------RDEFVIGRDDGNVLLAKQLDWETQNFYNLTISVTDGVN------EARTSLFVKV 1528 Query: 141 IDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ- 199 ID ND+ P+ SE Y V + E++ V I ++ A D D + + Y++ +Q Sbjct: 1529 IDINDHRPELSESIYHVEISENV-VEKGEAILQLHAQDLD--EDKKLFYSLHNAQSQASL 1585 Query: 200 --FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF 257 F +DSL+G ++L + LD E ++ + L + +D G+P++ N ++L+ + D ND+AP F Sbjct: 1586 QIFHVDSLTGTITLNEALDRETIQEHILTVMVKDQGTPAKRNFARVLVTVHDHNDHAPTF 1645 Query: 258 YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317 + + Q V E PIG ++V+V A D D G NA+L+Y+MT +GNV +IDP G Sbjct: 1646 ISEIIQGKVFETSPIGTAVVQVIAIDRDRGENAQLSYSMT----SGNVGNVFSIDPDLGT 1701 Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV--EL 375 + + +LD T ++Y LLV ATD G P S + F+ E+ E+ Sbjct: 1702 IRVARELDLATASEYILLVKATDHGSPALSNSIPVHVMVTMADNAPPRFVRSGAELAAEI 1761 Query: 376 AEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435 E+E G+ V + +A + L +EI GN F I G+I+ + LD++ + Sbjct: 1762 YENEEIGSFVKHI---EARSTSSLQFEIVSGNIGEAFFINPST--GVISTQERLDYEDVK 1816 Query: 436 RYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495 Y L+++AT G S V +++ D N+ AP F A YT V E A IG+ V ++T Sbjct: 1817 FYNLSIAATSMSGASAQCNVIVHVLDRNDNAPQFVQAVYTGQVSEAASIGSLVFSANSTS 1876 Query: 496 SDVGINAQITYS-LSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETMSGYLLTVTA 553 S + I A+ S L++ ++ + V ++F I+ TGAI T LLD ET+ + V Sbjct: 1877 SPLVIKAEDADSELNALLNYDIVEELPRKFFHIDSSTGAIRTVMLLDHETIPEFQFNVKV 1936 Query: 554 RDGGVPSLS--DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD-- 609 D G P LS T V I+V DVND P F+Q Y A ++ +V ++ A D D Sbjct: 1937 SDLGKPKLSSESTAKVIITVSDVNDCPPKFQQSDYNATVLLPTWKNVAVVKLEAHDPDST 1996 Query: 610 VGLNGRIHYELDPKDREEG-SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 + D D +G SF ID SG + N + + ++ L A DG S Sbjct: 1997 SAFTNQPSLRYDIIDGNQGQSFDIDSQSGALTVNNPENMKK--SYLLHVRASDG---KYS 2051 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 S V+IK+ +S VF+ + + ENS +T+ + N V +SI Sbjct: 2052 SVAQVNIKVAKSENSGLVFQKEVYEGTVVENSTKVSTVAVLNV--LGSALNEHVVFSIL- 2108 Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR---VEILVT 785 + + F + G A T + D E+ KYEL++ A S V V + V Sbjct: 2109 -NPTEMFVIGPTSG---AISTTGIRFDRET-IDKYELIVEANSQVPTQRVAHTIVNVTVL 2163 Query: 786 DVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRI-LSGNNANLILLNE 844 D+NDN P+ + D +V A D D D + R L + L +N Sbjct: 2164 DINDNCPIFVNLPYYAVVSVDAQKGDVIMKVHAIDLDSGDNGEVRYELKKGHGELFKVNR 2223 Query: 845 TTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEM 891 TG ++L L + + M + G++ + ++V++I M Sbjct: 2224 KTGEISLKQNLEGHNREYQLMIAAYDGGISPCSVEISVNVKVIDRSM 2270 Score = 273 bits (670), Expect = 4e-71 Identities = 233/848 (27%), Positives = 372/848 (43%), Gaps = 59/848 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I VLD ND P F Y S+ E A GT +L L A D D G N+++ Y IE TAD L Sbjct: 2363 ILVLDVNDCPPEFSQDSYNISISEAALFGTELLRLVARDNDTGINSKIRYAIENRTADEL 2422 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 D+F +D G + + SLD E + V A D+ P L Sbjct: 2423 GEN------------TLDLFHVDPEEGIVYLKRSLDHETADSHHFTVVAMDRGVP---SL 2467 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SSTA + + +ID NDN P+F + +Y + E+ + + A+D D+ + + Y Sbjct: 2468 SSTAHVWLTVIDMNDNPPKFEQSSYNCFLSEE--AERGQFVTVVSASDPDL-LDDKLVYT 2524 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I+GGN Q +SID +G ++L+ ++ + L + DG ++ ++ I I Sbjct: 2525 IVGGNDQQTYSIDQSTGIITLINMQNFADDKMTLLNVSVSDG---VYTSFARIKIEILPA 2581 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 N + P+F + + SV EN G + V A D D G + Y++ + DY Sbjct: 2582 NRHHPKFLNPVVEVSVLENQLPGKLVTSVLATDKDFGEYGTIEYSI-NSDYLKEF---FE 2637 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 ID +G + T LDRE +++ V A+DGG +S F+ + Sbjct: 2638 IDRENGDIVTKKSLDREKHKLFEIPVMASDGGG--KSGFVIVRVKVTDENDNSPVFLLKE 2695 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDN--RLHYEI---TGGNTRGRFSITSQNGRGLI-T 424 Y+ + + + + + A DADE + ++ Y I + F I G + Sbjct: 2696 YKASIYGNLTLNSAFLKVKALDADEGDAAKIIYSIFEPQNSEIKNIFGINPDTGAVFLKK 2755 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSD--TAMVQINITDANNYAPVFENAPYTASVFEDA 482 A+P + + + L V A D G S V+I I + P+FE V E + Sbjct: 2756 SAKPW---ETQPFQLFVRAQDKGLASHHVDVPVEIYIMGPEDIPPLFERKEDKFFVSETS 2812 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 IGT + + N+ +T L S A D F ++P+T +T + LDRE Sbjct: 2813 TIGTPITRLRTV---TNTNSTVTCRLVS-------AGDDFPFAVDPKTCRVTLSGNLDRE 2862 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 Y++ V A P L+ ++ + V+D ND+ P F+ Y+ + E+ GTS+ + Sbjct: 2863 VKDSYMIGVLAETDSSPPLTALAEITLQVLDENDHAPKFESNPYSIAVAENIEEGTSILK 2922 Query: 603 VGATDADVGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKALDRESVATHDLKAVAID 661 V A D D+G NG + Y E + F ID +G I + LD+E + + +A D Sbjct: 2923 VVAHDNDLGSNGEVRYSFGSDIGELANVFTIDAYTGWISSLVQLDKEQQPEYKFQVIATD 2982 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY--ISENSPIGTTIGEIRAHDPDEGPN 719 G P S V +K++D ND+P F S + + E++ GT + E+ D D N Sbjct: 2983 NGNPRHFSRTSVLVKLKDYNDNPSAFSSAESGYQATVKEDALPGTVVVELTTVDKDTELN 3042 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR 779 + + I GD + F++ + ++ LD E+ R +YEL++ + R Sbjct: 3043 TALDFYIISGDPRSQFAIRS-----TGQVYVAKALDRET-RDRYELLVVGTDGKFVFETR 3096 Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA--YDADVTDKLQYRILSGNNA 837 V + V DVNDN P ++ + P V A YD + KL++ + G N Sbjct: 3097 VIVQVLDVNDNPPYCLKYRYREVLSEGSHPGSYVLTVLATDYDDEPNAKLRFYLTGGKNE 3156 Query: 838 NLILLNET 845 L ET Sbjct: 3157 KFSLDKET 3164 Score = 264 bits (646), Expect = 3e-68 Identities = 228/807 (28%), Positives = 369/807 (45%), Gaps = 78/807 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D NDHSPVFE + Y + S + + A DQDIGKN +++Y+I+ Sbjct: 1321 VQVDDVNDHSPVFEEKFYMVQIPASPSLDKPLFQVLAHDQDIGKNGKIQYSIK------- 1373 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F+I +G + ++ + + + ++++ATD+ P Sbjct: 1374 ------------SGKGKGKFKIHPDTGMVYSQRGFEAGQ--EFEMIIRATDEGEPPRSHQ 1419 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + + V D+ N P F +V V E S ++A ++ATD D ++ Y Sbjct: 1420 ARISVQVVETPKDSPNPPVFKSLNQSVEVTE--SDKAGFLVALMQATDKD---GDSLWYD 1474 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I+ G+T+ +F I G+V L K LD+E Y L I DG + +R T L + + D+ Sbjct: 1475 IVEGDTRDEFVIGRDDGNVLLAKQLDWETQNFYNLTISVTDGVNEAR---TSLFVKVIDI 1531 Query: 251 NDNAPRFYTSLFQESVSEN-VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 ND+ P S++ +SEN V G +I+++ A D DE + +L Y++ + ++ + Sbjct: 1532 NDHRPELSESIYHVEISENVVEKGEAILQLHAQDLDE--DKKLFYSLHNAQSQASLQI-F 1588 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 +D +G + + LDRET ++ L V D G P + A F+ Sbjct: 1589 HVDSLTGTITLNEALDRETIQEHILTVMVKDQGTPAKRNFARVLVTVHDHNDHAPTFISE 1648 Query: 370 QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 + ++ E P GT VV + A D D E+ +L Y +T GN FSI G I VA+ Sbjct: 1649 IIQGKVFETSPIGTAVVQVIAIDRDRGENAQLSYSMTSGNVGNVFSIDPD--LGTIRVAR 1706 Query: 428 PLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVF--ENAPYTASVFEDAP 483 LD Y+L V ATD G S++ V + +T A+N P F A A ++E+ Sbjct: 1707 ELDLATASEYILLVKATDHGSPALSNSIPVHVMVTMADNAPPRFVRSGAELAAEIYENEE 1766 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 IG+ V I A+ T SL EI + + + F INP TG I+T + LD E Sbjct: 1767 IGSFV---------KHIEARSTSSLQFEIVSGNIG---EAFFINPSTGVISTQERLDYED 1814 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 + Y L++ A + S +V + V+D NDN P F Q +YT + E A +G+ V Sbjct: 1815 VKFYNLSIAAT--SMSGASAQCNVIVHVLDRNDNAPQFVQAVYTGQVSEAASIGSLVFSA 1872 Query: 604 GAT---------DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654 +T DAD LN ++Y++ ++ F ID ++G IRT LD E++ Sbjct: 1873 NSTSSPLVIKAEDADSELNALLNYDI-VEELPRKFFHIDSSTGAIRTVMLLDHETIPEFQ 1931 Query: 655 LKAVAIDGGTPPQS--STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 D G P S ST V I + D+ND PP F+ + + + ++ AH Sbjct: 1932 FNVKVSDLGKPKLSSESTAKVIITVSDVNDCPPKFQQSDYNATVLLPTWKNVAVVKLEAH 1991 Query: 713 DPDEGP----NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768 DPD + Y I G+ SF ++++ G+ + + E+ +K Y L +R Sbjct: 1992 DPDSTSAFTNQPSLRYDIIDGNQGQSFDIDSQSGA-------LTVNNPENMKKSYLLHVR 2044 Query: 769 AASPPLWNDVRVEILVTDVNDNAPVMK 795 A+ + +V I V ++ V + Sbjct: 2045 ASDGKYSSVAQVNIKVAKSENSGLVFQ 2071 Score = 263 bits (645), Expect = 4e-68 Identities = 239/891 (26%), Positives = 407/891 (45%), Gaps = 65/891 (7%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 H + V+D ND+ P FE Y + E A G V + A+D D+ + ++ YTI Sbjct: 2472 HVWLTVIDMNDNPPKFEQSSYNCFLSEEAERGQFVTVVSASDPDL-LDDKLVYTI----- 2525 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 + D Q + ID +G ++T ++ + T+L + VS Sbjct: 2526 --VGGND------------QQTYSIDQSTG-IITLINMQNFADDKMTLLNVS------VS 2564 Query: 128 DRL-SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 D + +S A I + I+ N ++P+F VSV E + ++ + ATD D G Sbjct: 2565 DGVYTSFARIKIEILPANRHHPKFLNPVVEVSVLE--NQLPGKLVTSVLATDKDFGEYGT 2622 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 I Y+I + F ID +GD+ K+LD E+ + + + + A DGG +S + + Sbjct: 2623 IEYSINSDYLKEFFEIDRENGDIVTKKSLDREKHKLFEIPVMASDGG--GKSGFVIVRVK 2680 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + D NDN+P F ++ S+ N+ + + ++V+A DADEG A++ Y++ + + Sbjct: 2681 VTDENDNSPVFLLKEYKASIYGNLTLNSAFLKVKALDADEGDAAKIIYSIFEPQ-NSEIK 2739 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 I+P +G V+ +QL V A D G F Sbjct: 2740 NIFGINPDTGAVFLKKSAKPWETQPFQLFVRAQDKGLASHHVDVPVEIYIMGPEDIPPLF 2799 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 + + ++E GTP+ L T + ++ + + F++ + R +T++ Sbjct: 2800 ERKEDKFFVSETSTIGTPITRL-RTVTNTNSTVTCRLVSAGDDFPFAVDPKTCR--VTLS 2856 Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQI--NITDANNYAPVFENAPYTASVFEDAPI 484 LD + + Y++ V A TA+ +I + D N++AP FE+ PY+ +V E+ Sbjct: 2857 GNLDREVKDSYMIGVLAETDSSPPLTALAEITLQVLDENDHAPKFESNPYSIAVAENIEE 2916 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 GT++L V A D+D+G N ++ YS S+I A F I+ TG I++ LD+E Sbjct: 2917 GTSILKVVAHDNDLGSNGEVRYSFGSDIGELA-----NVFTIDAYTGWISSLVQLDKEQQ 2971 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK--QQLYTANIMEDALVGTSVSQ 602 Y V A D G P T V + + D NDN F + Y A + EDAL GT V + Sbjct: 2972 PEYKFQVIATDNGNPRHFSRTSVLVKLKDYNDNPSAFSSAESGYQATVKEDALPGTVVVE 3031 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 + D D LN + + + D F I ++G + KALDRE+ ++L V DG Sbjct: 3032 LTTVDKDTELNTALDFYIISGD-PRSQFAI-RSTGQVYVAKALDRETRDRYELLVVGTDG 3089 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 ++ + +++ D+ND+PP +SE S G+ + + A D D+ PNA + Sbjct: 3090 KFVFETRVI---VQVLDVNDNPPYCLKYRYREVLSEGSHPGSYVLTVLATDYDDEPNAKL 3146 Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV--IRAASPPLWN-DVR 779 + + GG + FSL+ G L T+ LD ES + KY L ++ W + Sbjct: 3147 RFYLTGG-KNEKFSLDKETG----VLKTVGQLDRES-QAKYILTAHVQDRDKTSWECSSQ 3200 Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDAD--VTDKLQYRILSGNN 836 +EIL++D+NDNAP Q + VG +V A D D + K++Y L N Sbjct: 3201 LEILISDLNDNAPRF-SMQSYSATLPEDVEVGTLVTKVHATDDDIGINRKIRYEFLDSAN 3259 Query: 837 ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRL 886 + + ++ +G +TL+ L+ + + + D G ++ ++ L V + Sbjct: 3260 DHFV-ISPDSGIVTLAKPLDRETKAMYNVSIQAMDQGTPQLSSVTFLIVNV 3309 Score = 263 bits (644), Expect = 6e-68 Identities = 250/879 (28%), Positives = 387/879 (44%), Gaps = 70/879 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I +L N H P F E SV E G V ++ ATD+D G+ +EY+I +D Sbjct: 2575 KIEILPANRHHPKFLNPVVEVSVLENQLPGKLVTSVLATDKDFGEYGTIEYSI---NSDY 2631 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L ++ F ID +G ++T+ SLDREK + + V A+D Sbjct: 2632 L----------------KEFFEIDRENGDIVTKKSLDREKHKLFEIPVMASDGGGK---- 2671 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S + V + D+NDN P F K Y S+ ++++ N K+KA DAD G + I Y Sbjct: 2672 -SGFVIVRVKVTDENDNSPVFLLKEYKASIYGNLTL--NSAFLKVKALDADEGDAAKIIY 2728 Query: 190 AII-GGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 +I N++++ F I+ +G V L K+ + + ++L +RAQD G S + I Sbjct: 2729 SIFEPQNSEIKNIFGINPDTGAVFLKKSAKPWETQPFQLFVRAQDKGLASHHVDVPVEIY 2788 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 I D P F + VSE IG I R++ T+T + + D Sbjct: 2789 IMGPEDIPPLFERKEDKFFVSETSTIGTPITRLRTV-------TNTNSTVTCRLVSAGDD 2841 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 P +DP++ V SG LDRE + Y + V A PP +A A F Sbjct: 2842 FPFAVDPKTCRVTLSGNLDREVKDSYMIGVLAETDSSPPLTALAEITLQVLDENDHAPKF 2901 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS--ITSQNGRGLIT 424 Y + +AE+ GT ++ + A D D + + G+ G + T G I+ Sbjct: 2902 ESNPYSIAVAENIEEGTSILKVVAHDNDLGSNGEVRYSFGSDIGELANVFTIDAYTGWIS 2961 Query: 425 VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAP--YTASVFE 480 LD +Q+ Y V ATD+G V + + D N+ F +A Y A+V E Sbjct: 2962 SLVQLDKEQQPEYKFQVIATDNGNPRHFSRTSVLVKLKDYNDNPSAFSSAESGYQATVKE 3021 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 DA GT V+ ++ D D +N + + + IS + QF I TG + K LD Sbjct: 3022 DALPGTVVVELTTVDKDTELNTALDFYI---ISGDP----RSQFAIR-STGQVYVAKALD 3073 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 RET Y L V DG T V + V+DVNDN P + Y + E + G+ V Sbjct: 3074 RETRDRYELLVVGTDG---KFVFETRVIVQVLDVNDNPPYCLKYRYREVLSEGSHPGSYV 3130 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 V ATD D N ++ + L E+ F +D +GV++T LDRES A + L A Sbjct: 3131 LTVLATDYDDEPNAKLRFYLTGGKNEK--FSLDKETGVLKTVGQLDRESQAKYILTAHVQ 3188 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 D + + I I D+ND+ P F + + E+ +GT + ++ A D D G N Sbjct: 3189 DRDKTSWECSSQLEILISDLNDNAPRFSMQSYSATLPEDVEVGTLVTKVHATDDDIGINR 3248 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRA---ASPPLWN 776 + Y D +N + S + +VT+ LD E+ + Y + I+A +P L + Sbjct: 3249 KIRYEFL--DSANDHFVI----SPDSGIVTLAKPLDRET-KAMYNVSIQAMDQGTPQLSS 3301 Query: 777 DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPA--YDADVTDKLQYRILS 833 + + V D+NDN P + F + VG RV A D V + Y I+ Sbjct: 3302 VTFLIVNVQDINDNPPEFTS-KYYFARVPEIDAVGTEVARVLATSKDTGVNADVYYTIVG 3360 Query: 834 GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 GN ++ +G ++++ QL+ K + + DG Sbjct: 3361 GNEHKKFEIDTKSGVVSIAEQLDYERAKDYFLTIQAIDG 3399 Score = 261 bits (640), Expect = 2e-67 Identities = 241/808 (29%), Positives = 376/808 (46%), Gaps = 93/808 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D NDH+P F + + V E + GT V+ + A D+D G+NA++ Y++ Sbjct: 1633 VTVHDHNDHAPTFISEIIQGKVFETSPIGTAVVQVIAIDRDRGENAQLSYSM-------- 1684 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 V +VF ID G + LD + Y +LVKATD SP L Sbjct: 1685 -----------TSGNVGNVFSIDPDLGTIRVARELDLATASEYILLVKATDHGSPA---L 1730 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S++ +HV + ++ P+F ++ + + +N I + + S++++ Sbjct: 1731 SNSIPVHVMVTMADNAPPRFVRSGAELAAE----IYENEEIGSF-VKHIEARSTSSLQFE 1785 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD-GGSPSRSNTTQLLINIRD 249 I+ GN F I+ +G +S + LDYE V+ Y L I A G+ ++ N +++++ D Sbjct: 1786 IVSGNIGEAFFINPSTGVISTQERLDYEDVKFYNLSIAATSMSGASAQCN---VIVHVLD 1842 Query: 250 VNDNAPRFYTSLFQESVSENVPIG---------YSIVRVQAYDADEGVNAELTYTMTDKD 300 NDNAP+F +++ VSE IG S + ++A DAD +NA L Y + + Sbjct: 1843 RNDNAPQFVQAVYTGQVSEAASIGSLVFSANSTSSPLVIKAEDADSELNALLNYDIVE-- 1900 Query: 301 YTGNVDLP---ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRS--ATATXXXX 355 +LP ID +G + T LD ET ++Q V +D G P S +TA Sbjct: 1901 -----ELPRKFFHIDSSTGAIRTVMLLDHETIPEFQFNVKVSDLGKPKLSSESTAKVIIT 1955 Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN------RLHYEITGGNTR 409 F Y + VV L A D D + L Y+I GN Sbjct: 1956 VSDVNDCPPKFQQSDYNATVLLPTWKNVAVVKLEAHDPDSTSAFTNQPSLRYDIIDGNQG 2015 Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVF 469 F I SQ+ G +TV P + K + Y+L V A+D G S A V I + + N VF Sbjct: 2016 QSFDIDSQS--GALTVNNPENMK--KSYLLHVRASD-GKYSSVAQVNIKVAKSENSGLVF 2070 Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 + Y +V E++ +TV V++ S +N + +S + + + FVI P Sbjct: 2071 QKEVYEGTVVENSTKVSTVAVLNVLGS--ALNEHVVFS---------ILNPTEMFVIGPT 2119 Query: 530 TGAITTNKL-LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588 +GAI+T + DRET+ Y L V A T V ++V+D+NDN P+F Y A Sbjct: 2120 SGAISTTGIRFDRETIDKYELIVEANSQVPTQRVAHTIVNVTVLDINDNCPIFVNLPYYA 2179 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648 + DA G + +V A D D G NG + YEL K F ++ +G I + L+ Sbjct: 2180 VVSVDAQKGDVIMKVHAIDLDSGDNGEVRYEL--KKGHGELFKVNRKTGEISLKQNLEGH 2237 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG- 707 + + L A DGG P S + V++K+ I+ S PVF+ T + E+ + + + Sbjct: 2238 N-REYQLMIAAYDGGISPCSVEISVNVKV--IDRSMPVFDKQFYTDSVLESIEVHSPLAL 2294 Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELV 766 I+A P N + YSI G+D F+L+ G ++ +VD LDYE +K+YEL Sbjct: 2295 SIQAESP---LNRKLIYSITKGNDFEEFALDFNTG-----VIYVVDELDYEQ-KKQYELT 2345 Query: 767 IRAAS--PPLWNDVRVEILVTDVNDNAP 792 +RA ++ +V V ILV DVND P Sbjct: 2346 VRATDSVSGVYAEVLVSILVLDVNDCPP 2373 Score = 252 bits (617), Expect = 1e-64 Identities = 224/820 (27%), Positives = 368/820 (44%), Gaps = 53/820 (6%) Query: 86 VQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145 + + F I+ +G + T+ LD E V Y + + AT + S+ + V+++D ND Sbjct: 1791 IGEAFFINPSTGVISTQERLDYEDVKFYNLSIAATSMSGA-----SAQCNVIVHVLDRND 1845 Query: 146 NYPQFSEKTYTVSVDEDISV---------TDNPVIAKIKATDADVGANSAIRYAIIGGNT 196 N PQF + YT V E S+ T +P++ IKA DAD N+ + Y I+ Sbjct: 1846 NAPQFVQAVYTGQVSEAASIGSLVFSANSTSSPLV--IKAEDADSELNALLNYDIVEELP 1903 Query: 197 QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQLLINIRDVNDNA 254 + F IDS +G + V LD+E + ++ ++ D G P S +T +++I + DVND Sbjct: 1904 RKFFHIDSSTGAIRTVMLLDHETIPEFQFNVKVSDLGKPKLSSESTAKVIITVSDVNDCP 1963 Query: 255 PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR 314 P+F S + +V ++V+++A+D D ++ GN ID + Sbjct: 1964 PKFQQSDYNATVLLPTWKNVAVVKLEAHDPDSTSAFTNQPSLRYDIIDGNQGQSFDIDSQ 2023 Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374 SG + + + Y L V A+DG S+ A F YE Sbjct: 2024 SGALTVNNP--ENMKKSYLLHVRASDG---KYSSVAQVNIKVAKSENSGLVFQKEVYEGT 2078 Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434 + E+ + V L + + + + I N F I +G + T D + Sbjct: 2079 VVENSTKVSTVAVLNVLGSALNEHVVFSIL--NPTEMFVIGPTSG-AISTTGIRFDRETI 2135 Query: 435 RRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492 +Y L V A A +N+T D N+ P+F N PY A V DA G ++ V Sbjct: 2136 DKYELIVEANSQVPTQRVAHTIVNVTVLDINDNCPIFVNLPYYAVVSVDAQKGDVIMKVH 2195 Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552 A D D G N ++ Y L H + F +N +TG I+ + L+ Y L + Sbjct: 2196 AIDLDSGDNGEVRYELKKG--------HGELFKVNRKTGEISLKQNLEGHNRE-YQLMIA 2246 Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612 A DGG+ S V + V+D + PVF +Q YT +++E V + ++ + A+ L Sbjct: 2247 AYDGGISPCSVEISVNVKVID--RSMPVFDKQFYTDSVLESIEVHSPLAL--SIQAESPL 2302 Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672 N ++ Y + K + F +D +GVI LD E ++L A D + + V+ Sbjct: 2303 NRKLIYSIT-KGNDFEEFALDFNTGVIYVVDELDYEQKKQYELTVRATDSVSGVYAE-VL 2360 Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG--GD 730 V I + D+ND PP F D ISE + GT + + A D D G N+ + Y+I+ D Sbjct: 2361 VSILVLDVNDCPPEFSQDSYNISISEAALFGTELLRLVARDNDTGINSKIRYAIENRTAD 2420 Query: 731 DSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRA--ASPPLWNDVRVEILVTDV 787 + +L+ + +V + LD+E+ + V+ P L + V + V D+ Sbjct: 2421 ELGENTLDLFHVDPEEGIVYLKRSLDHETADSHHFTVVAMDRGVPSLSSTAHVWLTVIDM 2480 Query: 788 NDNAPVMKDFQIIFNNY-KDCFPVGPFGRV-PAYDADVTD-KLQYRILSGNNANLILLNE 844 NDN P + Q +N + + G F V A D D+ D KL Y I+ GN+ +++ Sbjct: 2481 NDNPPKFE--QSSYNCFLSEEAERGQFVTVVSASDPDLLDDKLVYTIVGGNDQQTYSIDQ 2538 Query: 845 TTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884 +TG +TL N K+ + VSV+DGV A +++ + Sbjct: 2539 STGIITLINMQNFADDKMTLLNVSVSDGVYTSFARIKIEI 2578 Score = 251 bits (614), Expect = 2e-64 Identities = 225/849 (26%), Positives = 379/849 (44%), Gaps = 57/849 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND P F+ Y A+V V+ L+A D D + ++ D Sbjct: 1954 ITVSDVNDCPPKFQQSDYNATVLLPTWKNVAVVKLEAHDPDSTSAFTNQPSLRYDIIDGN 2013 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F ID +SGAL + +K Y + V+A+D + Sbjct: 2014 QGQS---------------FDIDSQSGALTVNNPENMKK--SYLLHVRASD------GKY 2050 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SS A +++ + ++ F ++ Y +V E+ + + + + N + ++ Sbjct: 2051 SSVAQVNIKVAKSENSGLVFQKEVYEGTVVENSTKVSTVAVLNVLGS----ALNEHVVFS 2106 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I+ N F I SG +S D E + Y L++ A R T + + + D Sbjct: 2107 IL--NPTEMFVIGPTSGAISTTGIRFDRETIDKYELIVEANSQVPTQRVAHTIVNVTVLD 2164 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 +NDN P F + VS + G I++V A D D G N E+ Y + G+ +L Sbjct: 2165 INDNCPIFVNLPYYAVVSVDAQKGDVIMKVHAIDLDSGDNGEVRYELKK----GHGEL-F 2219 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 ++ ++G + L+ + +YQL++ A DGG P S + F Sbjct: 2220 KVNRKTGEISLKQNLEGHNR-EYQLMIAAYDGGISPCSVEISVNVKVIDRSMPV--FDKQ 2276 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 Y + E +P+ ++ + +L Y IT GN F++ G +I V L Sbjct: 2277 FYTDSVLESIEVHSPLALSIQAESPLNRKLIYSITKGNDFEEFALDFNTG--VIYVVDEL 2334 Query: 430 DFKQERRYVLTVSATDS-GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 D++Q+++Y LTV ATDS G +V I + D N+ P F Y S+ E A GT + Sbjct: 2335 DYEQKKQYELTVRATDSVSGVYAEVLVSILVLDVNDCPPEFSQDSYNISISEAALFGTEL 2394 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 L + A D+D GIN++I Y++ + ++E + F ++P+ G + + LD ET + Sbjct: 2395 LRLVARDNDTGINSKIRYAIENRTADELGENTLDLFHVDPEEGIVYLKRSLDHETADSHH 2454 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 TV A D GVPSLS T V ++V+D+NDN P F+Q Y + E+A G V+ V A+D Sbjct: 2455 FTVVAMDRGVPSLSSTAHVWLTVIDMNDNPPKFEQSSYNCFLSEEAERGQFVTVVSASDP 2514 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 D+ L+ ++ Y + ++ ++ ID ++G+I ++ ++ A + + + + Sbjct: 2515 DL-LDDKLVYTI-VGGNDQQTYSIDQSTGII---TLINMQNFADDKMTLLNVSVSDGVYT 2569 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 S + I+I N P F + + + EN G + + A D D G + YSI Sbjct: 2570 SFARIKIEILPANRHHPKFLNPVVEVSVLENQLPGKLVTSVLATDKDFGEYGTIEYSINS 2629 Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND-VRVEILVTDV 787 F ++ G ++VT LD E K +E+ + A+ + V V + VTD Sbjct: 2630 DYLKEFFEIDRENG----DIVTKKSLDREK-HKLFEIPVMASDGGGKSGFVIVRVKVTDE 2684 Query: 788 NDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGNNA---NLILL 842 NDN+PV + + Y + F +V A DAD D K+ Y I N+ N+ + Sbjct: 2685 NDNSPVFLLKEYKASIYGNLTLNSAFLKVKALDADEGDAAKIIYSIFEPQNSEIKNIFGI 2744 Query: 843 NETTGSMTL 851 N TG++ L Sbjct: 2745 NPDTGAVFL 2753 Score = 232 bits (568), Expect = 9e-59 Identities = 186/590 (31%), Positives = 281/590 (47%), Gaps = 39/590 (6%) Query: 105 LDREKVARYTVLVKATDQASPVSDR---LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE 161 L+RE+ +Y + +KAT + +R L + T+ V I+D ND P F Y +V E Sbjct: 160 LNRERKDKYVLEIKATARRHDGKNRVTLLEAQTTVAVTILDTNDLNPLFYPTEYEATVTE 219 Query: 162 DISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVR 221 D V + I K+ A DAD+G N I Y+ QF++ +SG V+L + L Y + Sbjct: 220 DTPVHKS--ILKVSAEDADLGTNGEIYYSF--AEKTEQFAVHPVSGVVTLTRPLRYVERP 275 Query: 222 SYRLVIRAQDGGS----PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277 Y L ++A+D G+ R++ +L I++R VN +AP E + + Y+IV Sbjct: 276 LYELTVQARDRGALYRMTPRASNARLTIHVRQVNLHAPEISVRHLPEILEHSNADTYAIV 335 Query: 278 RVQAYDADEGVNAEL-TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK-YQLL 335 RV D D G + E+ + + D G+ + P + LDRE + Y L Sbjct: 336 RV--LDRDTGPHGEIASLEIVAGDPDGHFRVRPLPTPGEYSIQVLKLLDREAAPQGYNLT 393 Query: 336 VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395 + A D G PPR + + F Y+V++ E P +PV+ L +DAD+ Sbjct: 394 LRAVDRGTPPRFSYKSVPVHLADLNDNAPIFSTEIYDVKVPETAPVNSPVIRLKVSDADQ 453 Query: 396 -DNRLHY-EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG----R 449 N L + EI GGN G F I + G++ A PLD + + Y LTVSA D G + Sbjct: 454 GKNALVFLEIVGGNEGGEFYINADT--GMLYTAVPLDAETKAFYTLTVSAVDQGNAGTRK 511 Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509 +A V+I + D N+ P FE + + E+ P GT+V V A D D G NA I+YS+ Sbjct: 512 QSSAKVKIYVIDTNDNDPEFEKSEMLVYLDENEPAGTSVCKVVARDKDSGENAYISYSID 571 Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS-GYLLTVTARDGGVP-SLSDTTDV 567 + I F I+ +G + T +LLD ETM YLL V A D G+P + Sbjct: 572 N-IKR-------VPFEIDHFSGVVKTKQLLDYETMKREYLLHVRANDWGLPYRRQSEIQL 623 Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627 I + +VNDN P F++ ++ VGT + V A D D G I Y + + Sbjct: 624 RIKLRNVNDNRPQFEKIDCVGHVSRYVQVGTEIITVSAIDFDAG--NIITYRIVSGGNAD 681 Query: 628 GSFVIDPASGVIRTNKALDRESVATHDL--KAVAIDGGTPPQSSTVIVHI 675 G F +DP SGV+ + A D + T ++ A DG +T+ +H+ Sbjct: 682 GCFALDPTSGVL--SVACDLSDLKTQEMIVNVTATDGTHFADVNTLRIHL 729 Score = 210 bits (512), Expect = 6e-52 Identities = 226/901 (25%), Positives = 381/901 (42%), Gaps = 84/901 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGA-SSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 + V+D NDH P Y + E G +L L A QD+ ++ ++ Y++ Sbjct: 1526 VKVIDINDHRPELSESIYHVEISENVVEKGEAILQLHA--QDLDEDKKLFYSLH------ 1577 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N + +F +D +G + +LDRE + + + V DQ +P Sbjct: 1578 -NAQSQASL---------QIFHVDSLTGTITLNEALDRETIQEHILTVMVKDQGTPAKRN 1627 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 A + V + D ND+ P F + V E + + ++ A D D G N+ + Y Sbjct: 1628 F---ARVLVTVHDHNDHAPTFISEIIQGKVFETSPI--GTAVVQVIAIDRDRGENAQLSY 1682 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 ++ GN FSID G + + + LD Y L+++A D GSP+ SN+ + + + Sbjct: 1683 SMTSGNVGNVFSIDPDLGTIRVARELDLATASEYILLVKATDHGSPALSNSIPVHVMVTM 1742 Query: 250 VNDNAPRFYTSLFQ--ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 ++ PRF S + + EN IG + ++A T ++ + +GN+ Sbjct: 1743 ADNAPPRFVRSGAELAAEIYENEEIGSFVKHIEARS---------TSSLQFEIVSGNIGE 1793 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 I+P +G + T +LD E Y L + AT SA F+ Sbjct: 1794 AFFINPSTGVISTQERLDYEDVKFYNLSIAATSMSGA--SAQCNVIVHVLDRNDNAPQFV 1851 Query: 368 PGQYEVELAEDEPPGTPVVTLTAT---------DADEDNR--LHYEITGGNTRGRFSITS 416 Y +++E G+ V + +T DAD + L+Y+I R F I S Sbjct: 1852 QAVYTGQVSEAASIGSLVFSANSTSSPLVIKAEDADSELNALLNYDIVEELPRKFFHIDS 1911 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNYAPVFENA 472 G I LD + + V +D G TA V I ++D N+ P F+ + Sbjct: 1912 STGA--IRTVMLLDHETIPEFQFNVKVSDLGKPKLSSESTAKVIITVSDVNDCPPKFQQS 1969 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 Y A+V V+ + A D D SL +I + + Q F I+ Q+GA Sbjct: 1970 DYNATVLLPTWKNVAVVKLEAHDPDSTSAFTNQPSLRYDIID---GNQGQSFDIDSQSGA 2026 Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592 +T N YLL V A DG S V I V ++ VF++++Y ++E Sbjct: 2027 LTVNN--PENMKKSYLLHVRASDG---KYSSVAQVNIKVAKSENSGLVFQKEVYEGTVVE 2081 Query: 593 DALVGTSVSQVGATDA-DVGLNGRIHYE-LDPKDREEGSFVIDPASGVIRTNKA-LDRES 649 ++ T VS V + LN + + L+P + FVI P SG I T DRE+ Sbjct: 2082 NS---TKVSTVAVLNVLGSALNEHVVFSILNPTEM----FVIGPTSGAISTTGIRFDRET 2134 Query: 650 VATHDLKAVAIDGGTPPQS-STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 + ++L V + P Q + IV++ + DIND+ P+F + +S ++ G I + Sbjct: 2135 IDKYEL-IVEANSQVPTQRVAHTIVNVTVLDINDNCPIFVNLPYYAVVSVDAQKGDVIMK 2193 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768 + A D D G N V Y +K G F + + G E+ +L E ++Y+L+I Sbjct: 2194 VHAIDLDSGDNGEVRYELKKGH-GELFKVNRKTG----EISLKQNL--EGHNREYQLMIA 2246 Query: 769 AASPPLWN-DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPAYDADVTDK 826 A + V + + V ++ + PV D Q ++ + V P ++ + K Sbjct: 2247 AYDGGISPCSVEISVNVKVIDRSMPVF-DKQFYTDSVLESIEVHSPLALSIQAESPLNRK 2305 Query: 827 LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886 L Y I GN+ L+ TG + + +L+ K + V TD V+ + A + +S+ + Sbjct: 2306 LIYSITKGNDFEEFALDFNTGVIYVVDELDYEQKKQYELTVRATDSVSGVYAEVLVSILV 2365 Query: 887 I 887 + Sbjct: 2366 L 2366 Score = 196 bits (479), Expect = 5e-48 Identities = 166/573 (28%), Positives = 267/573 (46%), Gaps = 36/573 (6%) Query: 324 LDRETQAKYQLLVTAT----DGGDPPR--SATATXXXXXXXXXXXXXXFMPGQYEVELAE 377 L+RE + KY L + AT DG + A T F P +YE + E Sbjct: 160 LNRERKDKYVLEIKATARRHDGKNRVTLLEAQTTVAVTILDTNDLNPLFYPTEYEATVTE 219 Query: 378 DEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437 D P ++ ++A DAD + +F++ +G ++T+ +PL + + Y Sbjct: 220 DTPVHKSILKVSAEDADLGTNGEIYYSFAEKTEQFAVHPVSG--VVTLTRPLRYVERPLY 277 Query: 438 VLTVSATDSGG------RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491 LTV A D G R+ A + I++ N +AP + + + E + T +V Sbjct: 278 ELTVQARDRGALYRMTPRASNARLTIHVRQVNLHAPEI-SVRHLPEILEHSN-ADTYAIV 335 Query: 492 SATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM-SGYLLT 550 D D G + +I SL ++ + H + + P +I KLLDRE GY LT Sbjct: 336 RVLDRDTGPHGEIA-SLEI-VAGDPDGHFRVRPLPTPGEYSIQVLKLLDREAAPQGYNLT 393 Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610 + A D G P V + + D+NDN P+F ++Y + E A V + V ++ +DAD Sbjct: 394 LRAVDRGTPPRFSYKSVPVHLADLNDNAPIFSTEIYDVKVPETAPVNSPVIRLKVSDADQ 453 Query: 611 GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID---GGTPPQ 667 G N + E+ E G F I+ +G++ T LD E+ A + L A+D GT Q Sbjct: 454 GKNALVFLEI-VGGNEGGEFYINADTGMLYTAVPLDAETKAFYTLTVSAVDQGNAGTRKQ 512 Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 SS V I + D ND+ P FE + Y+ EN P GT++ ++ A D D G NA + YSI Sbjct: 513 SSAK-VKIYVIDTNDNDPEFEKSEMLVYLDENEPAGTSVCKVVARDKDSGENAYISYSI- 570 Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL----WNDVRVEIL 783 D+ E S + T LDYE+ +++Y L +RA L +++++ I Sbjct: 571 --DNIKRVPFEIDHFSGVVK--TKQLLDYETMKREYLLHVRANDWGLPYRRQSEIQLRIK 626 Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNAN-LIL 841 + +VNDN P + + + VG V A D D + + YRI+SG NA+ Sbjct: 627 LRNVNDNRPQFEKIDCV-GHVSRYVQVGTEIITVSAIDFDAGNIITYRIVSGGNADGCFA 685 Query: 842 LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN 874 L+ T+G ++++ L+ + + V+ TDG + Sbjct: 686 LDPTSGVLSVACDLSDLKTQEMIVNVTATDGTH 718 Score = 186 bits (454), Expect = 6e-45 Identities = 157/517 (30%), Positives = 236/517 (45%), Gaps = 32/517 (6%) Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 T + + I D ND P FY + ++ +V+E+ P+ SI++V A DAD G N E+ Y+ +K Sbjct: 192 TTVAVTILDTNDLNPLFYPTEYEATVTEDTPVHKSILKVSAEDADLGTNGEIYYSFAEKT 251 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD----PPRSATATXXXXX 356 + P SG V + L + Y+L V A D G PR++ A Sbjct: 252 E------QFAVHPVSGVVTLTRPLRYVERPLYELTVQARDRGALYRMTPRASNARLTIHV 305 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRL-HYEITGGNTRGRFSI- 414 L +V + D + EI G+ G F + Sbjct: 306 RQVNLHAPEISVRHLPEILEHSNADTYAIVRVLDRDTGPHGEIASLEIVAGDPDGHFRVR 365 Query: 415 -TSQNGRGLITVAQPLDFK-QERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFE 470 G I V + LD + + Y LT+ A D G R V +++ D N+ AP+F Sbjct: 366 PLPTPGEYSIQVLKLLDREAAPQGYNLTLRAVDRGTPPRFSYKSVPVHLADLNDNAPIFS 425 Query: 471 NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 Y V E AP+ + V+ + +D+D G NA + + NE +F IN T Sbjct: 426 TEIYDVKVPETAPVNSPVIRLKVSDADQGKNALVFLEIVG--GNEG-----GEFYINADT 478 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFKQQLYTA 588 G + T LD ET + Y LTV+A D G + V+I V+D NDN+P F++ Sbjct: 479 GMLYTAVPLDAETKAFYTLTVSAVDQGNAGTRKQSSAKVKIYVIDTNDNDPEFEKSEMLV 538 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648 + E+ GTSV +V A D D G N I Y +D R F ID SGV++T + LD E Sbjct: 539 YLDENEPAGTSVCKVVARDKDSGENAYISYSIDNIKRV--PFEIDHFSGVVKTKQLLDYE 596 Query: 649 SVATHDLKAV-AIDGGTP-PQSSTVIVHIKIEDINDSPPVFES-DCLTFYISENSPIGTT 705 ++ L V A D G P + S + + IK+ ++ND+ P FE DC+ ++S +GT Sbjct: 597 TMKREYLLHVRANDWGLPYRRQSEIQLRIKLRNVNDNRPQFEKIDCVG-HVSRYVQVGTE 655 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 I + A D D G N + + + GG+ F+L+ G Sbjct: 656 IITVSAIDFDAG-NIITYRIVSGGNADGCFALDPTSG 691 Score = 174 bits (424), Expect = 3e-41 Identities = 122/402 (30%), Positives = 190/402 (47%), Gaps = 31/402 (7%) Query: 2 SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 SV F I +NV D ND+ P F + Y A V E + GT V + AT +D G NA+V YT Sbjct: 3301 SVTFLI---VNVQDINDNPPEFTSKYYFARVPEIDAVGTEVARVLATSKDTGVNADVYYT 3357 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121 I F ID +SG + LD E+ Y + ++A D Sbjct: 3358 I-------------------VGGNEHKKFEIDTKSGVVSIAEQLDYERAKDYFLTIQAID 3398 Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181 P L++ AT+++ ++D NDN P FS+ +Y S+ ED + + ++ A D D Sbjct: 3399 GGVP---PLTNHATVNITVLDSNDNAPMFSQASYRASIREDAKAGEK--VVQVFANDLDS 3453 Query: 182 GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 N + Y+I G+ Q QF+IDS SG ++++ LD EQ+ SY L + A+D G P+ SN Sbjct: 3454 NENGQVSYSIERGDRQKQFTIDSQSGQITVLAPLDREQIASYVLEVHAKDNGIPTLSNYV 3513 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 + I + D NDN P F + + V E+ P+GY++++ DAD NA YT + Sbjct: 3514 IVNIEVIDANDNPPLFAQNNYTTVVQEDKPLGYAVLKFTVTDADAEPNA-APYTFDFR-- 3570 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 +GN ++ + G + T+ + + KY L + D G PP + A Sbjct: 3571 SGNEGDAFRLE-QDGTLRTATKFSNRVKDKYLLHIRVFDNGSPPLYSDAWVLVKIIEESQ 3629 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEI 403 + + DE PG + + A+D D+ + L Y + Sbjct: 3630 YPPVITLLEININSYMDEYPGGVIGKVHASDKDQYDTLQYSL 3671 Score = 167 bits (406), Expect = 4e-39 Identities = 158/580 (27%), Positives = 262/580 (45%), Gaps = 59/580 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + +LD ND +P+F +YEA+V E ++L + A D D+G N E+ Y+ T Sbjct: 196 VTILDTNDLNPLFYPTEYEATVTEDTPVHKSILKVSAEDADLGTNGEIYYSFAEKT---- 251 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS--PVSD 128 + F + SG + L + Y + V+A D+ + ++ Sbjct: 252 -----------------EQFAVHPVSGVVTLTRPLRYVERPLYELTVQARDRGALYRMTP 294 Query: 129 RLSSTA-TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 R S+ TIHV + N + P+ S + + E + ++ A ++ D D G + I Sbjct: 295 RASNARLTIHVRQV--NLHAPEISVR----HLPEILEHSNADTYAIVRVLDRDTGPHGEI 348 Query: 188 R-YAIIGGNTQMQFSIDSLS--GDVSL--VKTLDYEQV-RSYRLVIRAQDGGSPSRSNTT 241 I+ G+ F + L G+ S+ +K LD E + Y L +RA D G+P R + Sbjct: 349 ASLEIVAGDPDGHFRVRPLPTPGEYSIQVLKLLDREAAPQGYNLTLRAVDRGTPPRFSYK 408 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 + +++ D+NDNAP F T ++ V E P+ ++R++ DAD+G NA + + Sbjct: 409 SVPVHLADLNDNAPIFSTEIYDVKVPETAPVNSPVIRLKVSDADQGKNALVFLEIVG--- 465 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD--PPRSATATXXXXXXXX 359 GN I+ +G +YT+ LD ET+A Y L V+A D G+ + ++A Sbjct: 466 -GNEGGEFYINADTGMLYTAVPLDAETKAFYTLTVSAVDQGNAGTRKQSSAKVKIYVIDT 524 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG 419 F + V L E+EP GT V + A D D + + N + R + Sbjct: 525 NDNDPEFEKSEMLVYLDENEPAGTSVCKVVARDKDSGENAYISYSIDNIK-RVPFEIDHF 583 Query: 420 RGLITVAQPLDFK-QERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYT 475 G++ Q LD++ +R Y+L V A D G R ++I + + N+ P FE Sbjct: 584 SGVVKTKQLLDYETMKREYLLHVRANDWGLPYRRQSEIQLRIKLRNVNDNRPQFEKIDCV 643 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 V +GT ++ VSA D D G N ITY + S + D F ++P +G ++ Sbjct: 644 GHVSRYVQVGTEIITVSAIDFDAG-NI-ITYRIVSG------GNADGCFALDPTSGVLSV 695 Query: 536 N-KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 L D +T ++ VTA DG +D + I +V+V Sbjct: 696 ACDLSDLKTQE-MIVNVTATDG--THFADVNTLRIHLVNV 732 Score = 113 bits (271), Expect = 9e-23 Identities = 102/342 (29%), Positives = 149/342 (43%), Gaps = 35/342 (10%) Query: 4 PFCIHQQIN--VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 P H +N VLD ND++P+F Y AS+RE A +G V+ + A D D +N +V Y+ Sbjct: 3403 PLTNHATVNITVLDSNDNAPMFSQASYRASIREDAKAGEKVVQVFANDLDSNENGQVSYS 3462 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121 IE D Q F ID +SG + A LDRE++A Y + V A D Sbjct: 3463 IE--RGDR-----------------QKQFTIDSQSGQITVLAPLDREQIASYVLEVHAKD 3503 Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181 P LS+ +++ +ID NDN P F++ YT V ED + + K TDAD Sbjct: 3504 NGIPT---LSNYVIVNIEVIDANDNPPLFAQNNYTTVVQEDKPL--GYAVLKFTVTDADA 3558 Query: 182 GANSA-IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240 N+A + GN F ++ G + Y L IR D GSP + Sbjct: 3559 EPNAAPYTFDFRSGNEGDAFRLEQ-DGTLRTATKFSNRVKDKYLLHIRVFDNGSPPLYSD 3617 Query: 241 TQLLINIRDVNDNAPRF-YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 +L+ I + + P + S + P G I +V A D D+ + + T Sbjct: 3618 AWVLVKIIEESQYPPVITLLEININSYMDEYP-GGVIGKVHASDKDQYDTLQYSLVPTSP 3676 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341 N DL ID G + +LD +Y++ V+ TDG Sbjct: 3677 S-RPNTDL-FQIDKLDGTLVALPRLD---IGEYRVNVSVTDG 3713 Score = 100 bits (240), Expect = 5e-19 Identities = 104/375 (27%), Positives = 164/375 (43%), Gaps = 37/375 (9%) Query: 438 VLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA--SVFED-APIGTTVLVVSAT 494 ++TVSA D + ++ I N F P + SV D + + T ++V+ T Sbjct: 656 IITVSAIDFDAGN---IITYRIVSGGNADGCFALDPTSGVLSVACDLSDLKTQEMIVNVT 712 Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT---V 551 +D G + +L + N A Q ++ +TG R+T LT Sbjct: 713 ATD-GTHFADVNTLRIHLVNVKRAQGPQSKLLTDETGGFEC-----RDTGVARRLTEAIA 766 Query: 552 TARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG 611 +A + S D + S N + P F + E A +G ++++ A D D+G Sbjct: 767 SAEKNNMRSSEDEYSMMPSRYGENVHAPEFLDFPNEIRVNESAPIGFVLARLAARDRDLG 826 Query: 612 LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671 NG++ Y + D + F IDP +G +R LDRE + L D G P +S++ Sbjct: 827 YNGKLVYGISAGD-SDSVFGIDPDTGELRLIGRLDREREDEYFLNITVYDLGKPQKSASR 885 Query: 672 IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD 731 ++ + + D+ND+ P FE +F +SE + GT I D D G NA V YS+ D Sbjct: 886 MLAVSVLDVNDNAPKFEKALASFRVSEAALNGTIIFRANTTDADLGENAQVAYSLV--TD 943 Query: 732 SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA--------------SPPLWND 777 ++ F ++ G L LD E + YEL IRA +P L+++ Sbjct: 944 TSDFRVDRTTG----VLTVFGKLDRER-QSSYELRIRATDKNGGNDKGEPDFDNPALYSE 998 Query: 778 VRVEILVTDVNDNAP 792 V + V DVNDNAP Sbjct: 999 ALVRVSVDDVNDNAP 1013 Score = 77.8 bits (183), Expect = 4e-12 Identities = 78/307 (25%), Positives = 133/307 (43%), Gaps = 30/307 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I V+D ND+ P FE + + E +GT+V + A D+D G+NA + Y+I+ + Sbjct: 518 KIYVIDTNDNDPEFEKSEMLVYLDENEPAGTSVCKVVARDKDSGENAYISYSIDNIK--- 574 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSD 128 + F ID SG + T+ LD E + R Y + V+A D P Sbjct: 575 -----------------RVPFEIDHFSGVVKTKQLLDYETMKREYLLHVRANDWGLPY-- 615 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 R S + + + + NDN PQF + V + V I + A D D G + I Sbjct: 616 RRQSEIQLRIKLRNVNDNRPQFEKIDCVGHVSRYVQV--GTEIITVSAIDFDAG--NIIT 671 Query: 189 YAII-GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL-LIN 246 Y I+ GGN F++D SG +S+ L + + + + A DG + NT ++ L+N Sbjct: 672 YRIVSGGNADGCFALDPTSGVLSVACDLSDLKTQEMIVNVTATDGTHFADVNTLRIHLVN 731 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVR-VQAYDADEGVNAELTYTMTDKDYTGNV 305 ++ + T + + + + + + + ++E Y+M Y NV Sbjct: 732 VKRAQGPQSKLLTDETGGFECRDTGVARRLTEAIASAEKNNMRSSEDEYSMMPSRYGENV 791 Query: 306 DLPITID 312 P +D Sbjct: 792 HAPEFLD 798 Score = 46.8 bits (106), Expect = 0.009 Identities = 18/47 (38%), Positives = 27/47 (57%), Gaps = 4/47 (8%) Query: 1537 CTCEAGRVGPQC---VSACELGPCGAAR-CVPDQTPKGYSCACEPGY 1579 C+C+ G G C ++ C GPC + C+PD + +GYSC C G+ Sbjct: 3891 CSCKEGYAGTHCEIVINECARGPCPVFKVCIPDSSVQGYSCQCPEGF 3937 >UniRef50_Q14517 Cluster: Cadherin-related tumor suppressor homolog precursor; n=49; Euteleostomi|Rep: Cadherin-related tumor suppressor homolog precursor - Homo sapiens (Human) Length = 4590 Score = 459 bits (1132), Expect = e-127 Identities = 407/1378 (29%), Positives = 639/1378 (46%), Gaps = 137/1378 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+SPVFE YEA + E G+ V+ ++A+D D G N +V Y+++ Sbjct: 2799 IQVKDANDNSPVFESSPYEAFIVENLPGGSRVIQIRASDADSGTNGQVMYSLD------- 2851 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 V + F I+ +G + T LD EK Y + V A+D + +L Sbjct: 2852 ---------QSQSVEVIESFAINMETGWITTLKELDHEKRDNYQIKVVASDHGEKI--QL 2900 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA-NSAIRY 189 SSTA + V + D ND+ P+F+ + Y +V ED VIA + TDAD N + Y Sbjct: 2901 SSTAIVDVTVTDVNDSPPRFTAEIYKGTVSEDDP--QGGVIAILSTTDADSEEINRQVTY 2958 Query: 190 AIIGGNTQMQFSIDSLSGD--VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 I GG+ QF+++++ + V + K LD E+ +Y L I A DG S++ + + Sbjct: 2959 FITGGDPLGQFAVETIQNEWKVYVKKPLDREKRDNYLLTITATDGTFSSKAIVE---VKV 3015 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 D NDN+P +L+ +++ E+V G I+++ A DAD NAE+TYT+ G+ Sbjct: 3016 LDANDNSPVCEKTLYSDTIPEDVLPGKLIMQISATDADIRSNAEITYTLL-----GSGAE 3070 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 ++P +G + TS LDRE QA Y LLV ATDGG R A+ F Sbjct: 3071 KFKLNPDTGELKTSTPLDREEQAVYHLLVRATDGGG--RFCQASIVVTLEDVNDNAPEFS 3128 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITV 425 Y + + E+ PGT + + ATDAD + ++ Y + + G+FSI +G +I + Sbjct: 3129 ADPYAITVFENTEPGTLLTRVQATDADAGLNRKILYSLID-SADGQFSINELSG--IIQL 3185 Query: 426 AQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 +PLD + + Y L++ A D G + T V +++ D N+ PVFE Y A+V ED Sbjct: 3186 EKPLDRELQAVYTLSLKAVDQGLPRRLTATGTVIVSVLDINDNPPVFEYREYGATVSEDI 3245 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 +GT VL V A D+ NA+ITYS+ S NE H + F I+ +TGA+ + LD E Sbjct: 3246 LVGTEVLQVYAASRDIEANAEITYSIIS--GNE----HGK-FSIDSKTGAVFIIENLDYE 3298 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 + Y LTV A DGG PSLSD V ++V D+NDN PVF Q YT I EDA++ SV Sbjct: 3299 SSHEYYLTVEATDGGTPSLSDVATVNVNVTDINDNTPVFSQDTYTTVISEDAVLEQSVIT 3358 Query: 603 VGATDADVGLNGRIHYELDPKDREEG-SFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 V A DAD N IHY + D +G SF IDP G ++ K LDRE+++ + L A D Sbjct: 3359 VMADDADGPSNSHIHYSI--IDGNQGSSFTIDPVRGEVKVTKLLDRETISGYTLTVQASD 3416 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA- 720 G+PP+ +T V+I + D+ND+ PVF + I EN P+G ++ ++ D D N Sbjct: 3417 NGSPPRVNTTTVNIDVSDVNDNAPVFSRGNYSVIIQENKPVGFSVLQLVVTDEDSSHNGP 3476 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRV 780 ++I G+D +F + + + + + D+ + K V P L + + Sbjct: 3477 PFFFTIVTGNDEKAFEVNPQGVLLTSSAIKRKEKDHYLLQVK---VADNGKPQLSSLTYI 3533 Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLI 840 +I V + + P + +I + + + G G++ A D DV D L Y L NL Sbjct: 3534 DIRVIEESIYPPAILPLEIFITSSGEEYSGGVIGKIHATDQDVYDTLTYS-LDPQMDNLF 3592 Query: 841 LLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRL 900 ++ T G + +L+ + VSVTDG A + + +R +T+EML ++I +R Sbjct: 3593 SVSSTGGKLIAHKKLDIG---QYLLNVSVTDGKFTTVADITVHIRQVTQEMLNHTIAIRF 3649 Query: 901 NDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEV 960 ++T E+F+ F L I+ + +I I S+Q L+V +P Sbjct: 3650 ANLTPEEFVGDYWRNFQRALRNILGVRRNDIQIVSLQSSEPHPH--LDVLLFVEKPG--- 3704 Query: 961 GVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFG 1020 S S L ++ T + + V++L +C C ++ C + Sbjct: 3705 ------SAQISTKQLLHKINSSVTDIEEIIGVRILNVFQKLCAGLDC-PWKFCDEKVSVD 3757 Query: 1021 NASGFVNSDSVL-FRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQC 1079 + +S + L F + C C EG C + CE D C GS+C Sbjct: 3758 ESVMSTHSTARLSFVTPRHHRAAVCLCKEG----RCPPV--HHGCEDDP----CPEGSEC 3807 Query: 1080 VA---RREGGILCQGCSIDAAYTTAVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQ 1136 V+ + +C ++ L S+ V LT K ++ ++L+ T Sbjct: 3808 VSDPWEEKHTCVCPSGRFGQCPGSSSMTLTGNSY-VKYRLTENENKLEMKLTMRLR--TY 3864 Query: 1137 TTSGLLLYNGRYNERHDFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEG-NVGDGS 1195 +T +++ Y D+ LE+ GR L++ F G G ++V+ V DG Sbjct: 3865 STHAVVM----YARGTDYSILEI---HHGR-----LQYKFDCGSGPGIVSVQSIQVNDGQ 3912 Query: 1196 WHTVEIEYFNRTITMILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRF 1255 WH V +E ++L D+V + +G A LK T + Sbjct: 3913 WHAVALEVNGNYARLVL---DQVHTASGTAPGTLK------------------TLNLDNY 3951 Query: 1256 LDLTGPLQIGGLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNS------YVADNGTLA- 1308 + G ++ G + S QV N F GC+ Y++ + + LNS ++ ++ ++ Sbjct: 3952 VFFGGHIRQQGTRH-GRSPQVGN-GFRGCMDSIYLNGQELPLNSKPRSYAHIEESVDVSP 4009 Query: 1309 GC-PEKRSRCSSAPCYNGAECS-DLWDTYICDCKEGHTGKDCADSTGP----PWRFGG 1360 GC C+S PC NG C+ Y C C + G C S P P +GG Sbjct: 4010 GCFLTATEDCASNPCQNGGVCNPSPAGGYYCKCSALYIGTHCEISVNPCSSNPCLYGG 4067 Score = 403 bits (992), Expect = e-110 Identities = 281/880 (31%), Positives = 449/880 (51%), Gaps = 54/880 (6%) Query: 3 VPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 V FC I + D ND++P F +YE ++ A+ GT+V+ A+D D G NA++ Y I Sbjct: 2580 VAFCTVNVI-LTDDNDNAPQFRATKYEVNIGSSAAKGTSVVK-SASDADEGSNADITYAI 2637 Query: 63 ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122 E AD+ V++ I+ SG + T+ SL + +T V+A D Sbjct: 2638 E---ADS--------------ESVKENLEINKLSGVITTKESLIGLENEFFTFFVRAVDN 2680 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 SP + S ++V I+ P+FSE YT +V ED+ V I I+A + Sbjct: 2681 GSPSKE---SVVLVYVKILPPEMQLPKFSEPFYTFTVSEDVPV--GTEIDLIRAEHSGTV 2735 Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ-DGGSPSRSNTT 241 S ++ N F ID SG + L K+LD+E + Y+ I A+ + Sbjct: 2736 LYSLVKGNTPESNRDESFVIDRQSGRLKLEKSLDHETTKWYQFSILARCTQDDHEMVASV 2795 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 + I ++D NDN+P F +S ++ + EN+P G +++++A DAD G N ++ Y++ D+ Sbjct: 2796 DVSIQVKDANDNSPVFESSPYEAFIVENLPGGSRVIQIRASDADSGTNGQVMYSL-DQSQ 2854 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR-SATATXXXXXXXXX 360 + V I+ +GW+ T +LD E + YQ+ V A+D G+ + S+TA Sbjct: 2855 SVEVIESFAINMETGWITTLKELDHEKRDNYQIKVVASDHGEKIQLSSTAIVDVTVTDVN 2914 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNR-LHYEITGGNTRGRFSITSQ 417 F Y+ ++ED+P G + L+ TDAD E NR + Y ITGG+ G+F++ + Sbjct: 2915 DSPPRFTAEIYKGTVSEDDPQGGVIAILSTTDADSEEINRQVTYFITGGDPLGQFAVETI 2974 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTAS 477 + V +PLD ++ Y+LT++ATD G S A+V++ + DAN+ +PV E Y+ + Sbjct: 2975 QNEWKVYVKKPLDREKRDNYLLTITATD-GTFSSKAIVEVKVLDANDNSPVCEKTLYSDT 3033 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 + ED G ++ +SATD+D+ NA+ITY+L + ++F +NP TG + T+ Sbjct: 3034 IPEDVLPGKLIMQISATDADIRSNAEITYTL--------LGSGAEKFKLNPDTGELKTST 3085 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LDRE + Y L V A DGG + +++ DVNDN P F Y + E+ G Sbjct: 3086 PLDREEQAVYHLLVRATDGG--GRFCQASIVVTLEDVNDNAPEFSADPYAITVFENTEPG 3143 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 T +++V ATDAD GLN +I Y L D +G F I+ SG+I+ K LDRE A + L Sbjct: 3144 TLLTRVQATDADAGLNRKILYSL--IDSADGQFSINELSGIIQLEKPLDRELQAVYTLSL 3201 Query: 658 VAIDGGTPPQ-SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 A+D G P + ++T V + + DIND+PPVFE +SE+ +GT + ++ A D Sbjct: 3202 KAVDQGLPRRLTATGTVIVSVLDINDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDI 3261 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPP 773 NA + YSI G++ FS++++ G+ + + +LDYES +Y L + A +P Sbjct: 3262 EANAEITYSIISGNEHGKFSIDSKTGA----VFIIENLDYESSH-EYYLTVEATDGGTPS 3316 Query: 774 LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRI 831 L + V + VTD+NDN PV +D V A DAD + Y I Sbjct: 3317 LSDVATVNVNVTDINDNTPVFSQDTYTTVISEDAVLEQSVITVMADDADGPSNSHIHYSI 3376 Query: 832 LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + GN + ++ G + ++ L+ T+ V +D Sbjct: 3377 IDGNQGSSFTIDPVRGEVKVTKLLDRETISGYTLTVQASD 3416 Score = 320 bits (787), Expect = 3e-85 Identities = 251/810 (30%), Positives = 390/810 (48%), Gaps = 69/810 (8%) Query: 1 MSVPFCIHQQINVLDCND--HSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEV 58 +S+ + ++ V+D N+ H PVF + +V+E A G+ V+T+ A D+D G++ E+ Sbjct: 1010 VSLSSTCYVEVEVVDVNENLHPPVFSSFVEKGTVKEDAPVGSLVMTVSAHDEDAGRDGEI 1069 Query: 59 EYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVK 118 Y+I D VF+I +G + T LDRE + Y + V Sbjct: 1070 RYSIR----------DGSGVG---------VFKIGEETGVIETSDRLDRESTSHYWLTVF 1110 Query: 119 ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178 ATDQ LSS I++ + D NDN PQ SE Y + E+ S D V+ +I+A D Sbjct: 1111 ATDQGVVP---LSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMEN-SPKDVSVV-QIEAFD 1165 Query: 179 ADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLV-KTLDYEQVRSYRLVIRAQDGGSPSR 237 D +N + Y I GN Q FSI +G ++ + LD EQ + L + D GSP + Sbjct: 1166 PDSSSNDKLMYKITSGNPQGFFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGSPPK 1225 Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS-------IVRVQAYDADEGVNA 290 S ++++ I D NDN P+F ++ + E + RV A D DEG NA Sbjct: 1226 STIARVIVKILDENDNKPQFLQKFYKIRLPEREKPDRERNARREPLYRVIATDKDEGPNA 1285 Query: 291 ELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL-VTATDGGDPPRSAT 349 E++Y++ D GN I+P++G V +S + +Y +L + A D G P +S+T Sbjct: 1286 EISYSIED----GNEHGKFFIEPKTG-VVSSKRFS--AAGEYDILSIKAVDNGRPQKSST 1338 Query: 350 ATXXXXXXXXXXXXX---XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG 406 F + + E +P + ++ L ++ITGG Sbjct: 1339 TRLHIEWISKPKQSLEPISFEESFFTFTVMESDPVAHMIGVISVEPPGIP--LWFDITGG 1396 Query: 407 NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYA 466 N F + G G I VA+PLD +Q+ Y LTV ATD G + V I + D N++ Sbjct: 1397 NYDSHFDV--DKGTGTIIVAKPLDAEQKSNYNLTVEATD-GTTTILTQVFIKVIDTNDHR 1453 Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 P F + Y + ED T +L +SA D D ++ Y+L S S + ++ ++F + Sbjct: 1454 PQFSTSKYEVVIPEDTAPETEILQISAVDQDE--KNKLIYTLQS--SRDPLSL--KKFRL 1507 Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586 +P TG++ T++ LD E +S LTV RD VP + + ++V D ND+ P F Y Sbjct: 1508 DPATGSLYTSEKLDHEAVSPAHLTVMVRDQDVPVKRNFARIVVNVSDTNDHAPWFTASSY 1567 Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD--REEGSFVIDPASGVIRTNKA 644 + E A VG+ V QV A D D G N + Y ++ + SF+IDP G I+T K Sbjct: 1568 KGRVYESAAVGSVVLQVTALDKDKGKNAEVLYSIESGNIGNIGNSFMIDPVLGSIKTAKE 1627 Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 LDR + A +DL A D G+PP S V I + +++ P F S + +SE IG+ Sbjct: 1628 LDRSNQAEYDLMVKATDKGSPPMSEITSVRIFVTIADNASPKFTSKEYSVELSETVSIGS 1687 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764 +G + AH + V Y IK G+ ++F + G+ ++T LD+E+ Y Sbjct: 1688 FVGMVTAHS-----QSSVVYEIKDGNTGDAFDINPHSGT----IITQKALDFET-LPIYT 1737 Query: 765 LVIRAAS-PPLWNDVRVEILVTDVNDNAPV 793 L+I+ + L + V + + D NDNAPV Sbjct: 1738 LIIQGTNMAGLSTNTTVLVHLQDENDNAPV 1767 Score = 319 bits (784), Expect = 6e-85 Identities = 249/814 (30%), Positives = 394/814 (48%), Gaps = 56/814 (6%) Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 D F I+ SG ++T+ +LD E + YT++++ T+ A LS+ T+ V++ D+NDN Sbjct: 1711 DAFDINPHSGTIITQKALDFETLPIYTLIIQGTNMAG-----LSTNTTVLVHLQDENDNA 1765 Query: 148 PQFSEKTYTVSVDEDISV-----TDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI 202 P F + YT + E S+ TD V I+A DAD +N+ + Y I+ + F+I Sbjct: 1766 PVFMQAEYTGLISESASINSVVLTDRNVPLVIRAADADKDSNALLVYHIVEPSVHTYFAI 1825 Query: 203 DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS--RSNTTQLLINIRDVNDNAPRFYTS 260 DS +G + V +LDYE+ + ++ D G+P + +++ D+ND P F Sbjct: 1826 DSSTGAIHTVLSLDYEETSIFHFTVQVHDMGTPRLFAEYAANVTVHVIDINDCPPVFAKP 1885 Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT 320 L++ S+ G ++ V A DAD ++L Y++T+ GN+ ++D ++G + Sbjct: 1886 LYEASLLLPTYKGVKVITVNATDADSSAFSQLIYSITE----GNIGEKFSMDYKTGALTV 1941 Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX-FMPGQYEVELAEDE 379 Q + +++Y+L V A+DG R A T F Y + E+ Sbjct: 1942 --QNTTQLRSRYELTVRASDG----RFAGLTSVKINVKESKESHLKFTQDVYSAVVKENS 1995 Query: 380 PPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL 439 + +TA + + L Y I N RF I+ +G L T P D +Q+ + + Sbjct: 1996 TEAETLAVITAIGSPINEPLFYHIL--NPDRRFKISRTSGV-LSTTGTPFDREQQEAFDV 2052 Query: 440 TVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497 V + S A +V++ + D N+ APVF N PY A V D +G + V+A D D Sbjct: 2053 VVEVIEEHKPSAVAHVVVKVIVEDQNDNAPVFVNLPYYAVVKVDTEVGHVIRYVTAVDRD 2112 Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG-YLLTVTARDG 556 G N ++ Y L H + F I P G I+ K + +T++ YL+TV A+DG Sbjct: 2113 SGRNGEVHYYLKE---------HHEHFQIGP-LGEISLKKQFELDTLNKEYLVTVVAKDG 2162 Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616 G P+ S V I+V+ N PVF++ Y+A I E V + V V A + GL ++ Sbjct: 2163 GNPAFSAEVIVPITVM--NKAMPVFEKPFYSAEIAESIQVHSPVVHVQANSPE-GL--KV 2217 Query: 617 HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676 Y + D F I+ +GVI LD E+ + L A D T + V V I Sbjct: 2218 FYSITDGD-PFSQFTINFNTGVINVIAPLDFEAHPAYKLSIRATDSLTGAHAE-VFVDII 2275 Query: 677 IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736 ++DIND+PPVF +SE S IGT++ ++RA D D PN + Y + G + Sbjct: 2276 VDDINDNPPVFAQQSYAVTLSEASVIGTSVVQVRATDSDSEPNRGISYQMFGNHSKSHDH 2335 Query: 737 LETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPV 793 + L+ LDYE R ++ + +RA P L +DV V + VTD+N N P+ Sbjct: 2336 FHVDSSTGLISLLR--TLDYEQSR-QHTIFVRAVDGGMPTLSSDVIVTVDVTDLNGNPPL 2392 Query: 794 MKDFQIIFNNYKDCFPVGPFGR-VPAYDADVT--DKLQYRILSGNNANLILLNETTGSMT 850 + QI + P G F V AYDAD + DKLQY ILSGN+ +++ TG +T Sbjct: 2393 FEQ-QIYEARISEHAPHGHFVTCVKAYDADSSDIDKLQYSILSGNDHKHFVIDSATGIIT 2451 Query: 851 LSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884 LS + ++ +SV+DGV + ++V Sbjct: 2452 LSNLHRHALKPFYSLNLSVSDGVFRSSTQVHVTV 2485 Score = 312 bits (766), Expect = 9e-83 Identities = 259/893 (29%), Positives = 413/893 (46%), Gaps = 93/893 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++++ D ND+ P F Y VRE GT ++ L+A D D+G++ +V Y++ Sbjct: 914 KVSLEDVNDNPPTFIPPNYRVKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSL------- 966 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L+ + F +D SGA+ LD EK Y + V+A D+ PVS Sbjct: 967 LDHGEGN-------------FDVDKLSGAVRIVQQLDFEKKQVYNLTVRAKDKGKPVS-- 1011 Query: 130 LSSTATIHVNIIDDNDNY--PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 LSST + V ++D N+N P FS +V ED V ++ + A D D G + I Sbjct: 1012 LSSTCYVEVEVVDVNENLHPPVFSSFVEKGTVKEDAPV--GSLVMTVSAHDEDAGRDGEI 1069 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 RY+I G+ F I +G + LD E Y L + A D G S+ ++ I + Sbjct: 1070 RYSIRDGSGVGVFKIGEETGVIETSDRLDRESTSHYWLTVFATDQGVVPLSSFIEIYIEV 1129 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 DVNDNAP+ ++ + EN P S+V+++A+D D N +L Y +T +GN Sbjct: 1130 EDVNDNAPQTSEPVYYPEIMENSPKDVSVVQIEAFDPDSSSNDKLMYKIT----SGNPQG 1185 Query: 308 PITIDPRSGWV-YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 +I P++G + TS +LDRE Q ++ L VT TD G PP+S A F Sbjct: 1186 FFSIHPKTGLITTTSRKLDREQQDEHILEVTVTDNGSPPKSTIARVIVKILDENDNKPQF 1245 Query: 367 MPGQYEVELAEDEPPG-------TPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQ 417 + Y++ L E E P P+ + ATD DE + + Y I GN G+F I + Sbjct: 1246 LQKFYKIRLPEREKPDRERNARREPLYRVIATDKDEGPNAEISYSIEDGNEHGKFFIEPK 1305 Query: 418 NGRGLITVAQPLDFKQERRY-VLTVSATDSGGRSDTAMVQINI----TDANNYAPV-FEN 471 G V F Y +L++ A D+G ++ +++I + P+ FE Sbjct: 1306 TG-----VVSSKRFSAAGEYDILSIKAVDNGRPQKSSTTRLHIEWISKPKQSLEPISFEE 1360 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 + +T +V E P+ + V+S + + IT ++D F ++ TG Sbjct: 1361 SFFTFTVMESDPVAHMIGVISVEPPGIPLWFDIT-----------GGNYDSHFDVDKGTG 1409 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 I K LD E S Y LTV A DG L T V I V+D ND+ P F Y I Sbjct: 1410 TIIVAKPLDAEQKSNYNLTVEATDGTTTIL---TQVFIKVIDTNDHRPQFSTSKYEVVIP 1466 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYEL----DPKDREEGSFVIDPASGVIRTNKALDR 647 ED T + Q+ A D D ++ Y L DP ++ F +DPA+G + T++ LD Sbjct: 1467 EDTAPETEILQISAVDQDE--KNKLIYTLQSSRDPLSLKK--FRLDPATGSLYTSEKLDH 1522 Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 E+V+ L + D P + + + + + D ND P F + + E++ +G+ + Sbjct: 1523 EAVSPAHLTVMVRDQDVPVKRNFARIVVNVSDTNDHAPWFTASSYKGRVYESAAVGSVVL 1582 Query: 708 EIRAHDPDEGPNAVVHYSIKG---GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764 ++ A D D+G NA V YSI+ G+ NSF ++ GS K T +LD S + +Y+ Sbjct: 1583 QVTALDKDKGKNAEVLYSIESGNIGNIGNSFMIDPVLGSIK----TAKELD-RSNQAEYD 1637 Query: 765 LVIRA---ASPPLWNDVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFPVGPF-GRVPA 818 L+++A SPP+ V I VT ++ +P K++ + + +G F G V A Sbjct: 1638 LMVKATDKGSPPMSEITSVRIFVTIADNASPKFTSKEYSV---ELSETVSIGSFVGMVTA 1694 Query: 819 YDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + + Y I GN + +N +G++ L+ + T+ + T+ Sbjct: 1695 HS---QSSVVYEIKDGNTGDAFDINPHSGTIITQKALDFETLPIYTLIIQGTN 1744 Score = 300 bits (736), Expect = 4e-79 Identities = 226/718 (31%), Positives = 356/718 (49%), Gaps = 44/718 (6%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDD--NDNY 147 F I+ +G + A LD E Y + ++ATD + + A + V+II D NDN Sbjct: 2230 FTINFNTGVINVIAPLDFEAHPAYKLSIRATDSLT------GAHAEVFVDIIVDDINDNP 2283 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ--FSIDSL 205 P F++++Y V++ E SV V+ +++ATD+D N I Y + G +++ F +DS Sbjct: 2284 PVFAQQSYAVTLSE-ASVIGTSVV-QVRATDSDSEPNRGISYQMFGNHSKSHDHFHVDSS 2341 Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265 +G +SL++TLDYEQ R + + +RA DGG P+ S+ + +++ D+N N P F +++ Sbjct: 2342 TGLISLLRTLDYEQSRQHTIFVRAVDGGMPTLSSDVIVTVDVTDLNGNPPLFEQQIYEAR 2401 Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325 +SE+ P G+ + V+AYDAD +L Y++ +GN ID +G + S Sbjct: 2402 ISEHAPHGHFVTCVKAYDADSSDIDKLQYSI----LSGNDHKHFVIDSATGIITLSNLHR 2457 Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 + Y L ++ +DG RS+T F+ +YEVELAE+ P T V Sbjct: 2458 HALKPFYSLNLSVSDG--VFRSSTQV-HVTVIGGNLHSPAFLQNEYEVELAENAPLHTLV 2514 Query: 386 VTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV-- 441 + + TD D + Y I + RF I N RG I + LD + V++V Sbjct: 2515 MEVKTTDGDSGIYGHVTYHIVNDFAKDRFYI---NERGQIFTLEKLDRETPAEKVISVRL 2571 Query: 442 SATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501 A D+GG+ V + +TD N+ AP F Y ++ A GT+V V SA+D+D G N Sbjct: 2572 MAKDAGGKVAFCTVNVILTDDNDNAPQFRATKYEVNIGSSAAKGTSV-VKSASDADEGSN 2630 Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL 561 A ITY++ E +E+V + IN +G ITT + L + V A D G PS Sbjct: 2631 ADITYAI--EADSESV---KENLEINKLSGVITTKESLIGLENEFFTFFVRAVDNGSPSK 2685 Query: 562 SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621 V + ++ P F + YT + ED VGT + + A + L + Sbjct: 2686 ESVVLVYVKILPPEMQLPKFSEPFYTFTVSEDVPVGTEIDLIRAEHSGTVLYSLVKGNTP 2745 Query: 622 PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA-IDGGTPPQSSTVIVHIKIEDI 680 +R+E SFVID SG ++ K+LD E+ + +A ++V V I+++D Sbjct: 2746 ESNRDE-SFVIDRQSGRLKLEKSLDHETTKWYQFSILARCTQDDHEMVASVDVSIQVKDA 2804 Query: 681 NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL--E 738 ND+ PVFES +I EN P G+ + +IRA D D G N V YS+ D S S + Sbjct: 2805 NDNSPVFESSPYEAFIVENLPGGSRVIQIRASDADSGTNGQVMYSL---DQSQSVEVIES 2861 Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRAASP----PLWNDVRVEILVTDVNDNAP 792 + + T+ +LD+E R Y++ + A+ L + V++ VTDVND+ P Sbjct: 2862 FAINMETGWITTLKELDHEK-RDNYQIKVVASDHGEKIQLSSTAIVDVTVTDVNDSPP 2918 Score = 299 bits (735), Expect = 5e-79 Identities = 254/880 (28%), Positives = 400/880 (45%), Gaps = 78/880 (8%) Query: 17 NDHSPVFEMQQYEA-SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDA 75 N H P F V+E G++V+ + +TD D G N ++ Y + D+ Sbjct: 710 NAHIPQFRSTLPTGIQVKENQPVGSSVIFMNSTDLDTGFNGKLVYAVSGGNEDSC----- 764 Query: 76 XXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTAT 135 F ID +G L + LDRE +YT+ + D P + ++ Sbjct: 765 --------------FMIDMETGMLKILSPLDRETTDKYTLNITVYDLGIP---QKAAWRL 807 Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195 +HV ++D NDN P+F +++Y V V ED V + I +++ATD D+G N + Y+I+ Sbjct: 808 LHVVVVDANDNPPEFLQESYFVEVSEDKEV--HSEIIQVEATDKDLGPNGHVTYSILTDT 865 Query: 196 TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG--SPSRSNTTQLLINIRDVNDN 253 FSIDS++G V++ + LD E + L I A+D P +T + +++ DVNDN Sbjct: 866 D--TFSIDSVTGVVNIARPLDRELQHEHSLKIEARDQAREEPQLFSTVVVKVSLEDVNDN 923 Query: 254 APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313 P F ++ V E++P G I+ ++A+D D G + ++ Y++ D GN D +D Sbjct: 924 PPTFIPPNYRVKVREDLPEGTVIMWLEAHDPDLGQSGQVRYSLLDHG-EGNFD----VDK 978 Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX---XFMPGQ 370 SG V QLD E + Y L V A D G P ++ F Sbjct: 979 LSGAVRIVQQLDFEKKQVYNLTVRAKDKGKPVSLSSTCYVEVEVVDVNENLHPPVFSSFV 1038 Query: 371 YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 + + ED P G+ V+T++A D D D + Y I G+ G F I + G+I + Sbjct: 1039 EKGTVKEDAPVGSLVMTVSAHDEDAGRDGEIRYSIRDGSGVGVFKIGEET--GVIETSDR 1096 Query: 429 LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD + Y LTV ATD G S + I + D N+ AP Y + E++P Sbjct: 1097 LDRESTSHYWLTVFATDQGVVPLSSFIEIYIEVEDVNDNAPQTSEPVYYPEIMENSPKDV 1156 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKLLDRETMS 545 +V+ + A D D N ++ Y ++S + F I+P+TG I TT++ LDRE Sbjct: 1157 SVVQIEAFDPDSSSNDKLMYKITS-------GNPQGFFSIHPKTGLITTTSRKLDREQQD 1209 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS------ 599 ++L VT D G P S V + ++D NDN+P F Q+ Y + E Sbjct: 1210 EHILEVTVTDNGSPPKSTIARVIVKILDENDNKPQFLQKFYKIRLPEREKPDRERNARRE 1269 Query: 600 -VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 + +V ATD D G N I Y ++ E G F I+P +GV+ + + + +D+ ++ Sbjct: 1270 PLYRVIATDKDEGPNAEISYSIE-DGNEHGKFFIEPKTGVVSSKRF---SAAGEYDILSI 1325 Query: 659 -AIDGGTPPQSSTVIVHIK-IEDINDS--PPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 A+D G P +SST +HI+ I S P FE TF + E+ P+ IG I Sbjct: 1326 KAVDNGRPQKSSTTRLHIEWISKPKQSLEPISFEESFFTFTVMESDPVAHMIGVISV--- 1382 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL 774 E P + + I GG+ + F ++ G+ ++ LD E + Y L + A Sbjct: 1383 -EPPGIPLWFDITGGNYDSHFDVDKGTGT----IIVAKPLDAEQ-KSNYNLTVEATDGTT 1436 Query: 775 WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSG 834 +V I V D ND+ P + +D P ++ A D D +KL Y + S Sbjct: 1437 TILTQVFIKVIDTNDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQDEKNKLIYTLQSS 1496 Query: 835 N---NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + L+ TGS+ S +L+ A + V V D Sbjct: 1497 RDPLSLKKFRLDPATGSLYTSEKLDHEAVSPAHLTVMVRD 1536 Score = 289 bits (709), Expect = 7e-76 Identities = 211/673 (31%), Positives = 332/673 (49%), Gaps = 56/673 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ VLD ND+SPV E Y ++ E G ++ + ATD DI NAE+ YT+ Sbjct: 3012 EVKVLDANDNSPVCEKTLYSDTIPEDVLPGKLIMQISATDADIRSNAEITYTL------- 3064 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + F+++ +G L T LDRE+ A Y +LV+ATD Sbjct: 3065 -------------LGSGAEKFKLNPDTGELKTSTPLDREEQAVYHLLVRATDGGGRFCQ- 3110 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 A+I V + D NDN P+FS Y ++V E + ++ +++ATDAD G N I Y Sbjct: 3111 ----ASIVVTLEDVNDNAPEFSADPYAITVFE--NTEPGTLLTRVQATDADAGLNRKILY 3164 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT-QLLINIR 248 ++I + QFSI+ LSG + L K LD E Y L ++A D G P R T +++++ Sbjct: 3165 SLI-DSADGQFSINELSGIIQLEKPLDRELQAVYTLSLKAVDQGLPRRLTATGTVIVSVL 3223 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D+NDN P F + +VSE++ +G +++V A D NAE+TY++ +GN Sbjct: 3224 DINDNPPVFEYREYGATVSEDILVGTEVLQVYAASRDIEANAEITYSI----ISGNEHGK 3279 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 +ID ++G V+ LD E+ +Y L V ATDGG P S AT F Sbjct: 3280 FSIDSKTGAVFIIENLDYESSHEYYLTVEATDGGTPSLSDVATVNVNVTDINDNTPVFSQ 3339 Query: 369 GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 Y ++ED V+T+ A DAD ++ +HY I GN F+I RG + V Sbjct: 3340 DTYTTVISEDAVLEQSVITVMADDADGPSNSHIHYSIIDGNQGSSFTIDPV--RGEVKVT 3397 Query: 427 QPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 + LD + Y LTV A+D+G R +T V I+++D N+ APVF Y+ + E+ P+ Sbjct: 3398 KLLDRETISGYTLTVQASDNGSPPRVNTTTVNIDVSDVNDNAPVFSRGNYSVIIQENKPV 3457 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 G +VL + TD D N + + N+ ++ F +NPQ G + T+ + R+ Sbjct: 3458 GFSVLQLVVTDEDSSHNGP-PFFFTIVTGND-----EKAFEVNPQ-GVLLTSSAIKRKEK 3510 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP-VFKQQLYTANIMEDALVGTSVSQV 603 YLL V D G P LS T ++I V++ + P + +++ + E+ G + ++ Sbjct: 3511 DHYLLQVKVADNGKPQLSSLTYIDIRVIEESIYPPAILPLEIFITSSGEE-YSGGVIGKI 3569 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 ATD DV + Y LDP + + F + G + +K LD + + L V++ G Sbjct: 3570 HATDQDV--YDTLTYSLDP--QMDNLFSVSSTGGKLIAHKKLD---IGQY-LLNVSVTDG 3621 Query: 664 TPPQSSTVIVHIK 676 + + VHI+ Sbjct: 3622 KFTTVADITVHIR 3634 Score = 289 bits (708), Expect = 1e-75 Identities = 258/883 (29%), Positives = 412/883 (46%), Gaps = 74/883 (8%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72 V+D ND+ P F + Y V E + ++ ++ATD+D+G N V Y+I DT Sbjct: 812 VVDANDNPPEFLQESYFVEVSEDKEVHSEIIQVEATDKDLGPNGHVTYSI---LTDT--- 865 Query: 73 EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132 D F ID +G + LDRE +++ ++A DQA +L S Sbjct: 866 ---------------DTFSIDSVTGVVNIARPLDRELQHEHSLKIEARDQARE-EPQLFS 909 Query: 133 TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192 T + V++ D NDN P F Y V V ED+ + VI ++A D D+G + +RY+++ Sbjct: 910 TVVVKVSLEDVNDNPPTFIPPNYRVKVREDL--PEGTVIMWLEAHDPDLGQSGQVRYSLL 967 Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP-SRSNTTQLLINIRDVN 251 + + F +D LSG V +V+ LD+E+ + Y L +RA+D G P S S+T + + + DVN Sbjct: 968 -DHGEGNFDVDKLSGAVRIVQQLDFEKKQVYNLTVRAKDKGKPVSLSSTCYVEVEVVDVN 1026 Query: 252 DNA-PRFYTSLFQE-SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 +N P ++S ++ +V E+ P+G ++ V A+D D G + E+ Y++ D G Sbjct: 1027 ENLHPPVFSSFVEKGTVKEDAPVGSLVMTVSAHDEDAGRDGEIRYSIRDGSGVG----VF 1082 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 I +G + TS +LDRE+ + Y L V ATD G P S+ Sbjct: 1083 KIGEETGVIETSDRLDRESTSHYWLTVFATDQGVVPLSSFIEIYIEVEDVNDNAPQTSEP 1142 Query: 370 QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 Y E+ E+ P VV + A D D +++L Y+IT GN +G FSI + G + T ++ Sbjct: 1143 VYYPEIMENSPKDVSVVQIEAFDPDSSSNDKLMYKITSGNPQGFFSIHPKTGL-ITTTSR 1201 Query: 428 PLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE-DAP- 483 LD +Q+ ++L V+ TD+G +S A V + I D N+ P F Y + E + P Sbjct: 1202 KLDREQQDEHILEVTVTDNGSPPKSTIARVIVKILDENDNKPQFLQKFYKIRLPEREKPD 1261 Query: 484 -----IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 + V ATD D G NA+I+YS+ E NE H +F I P+TG +++ + Sbjct: 1262 RERNARREPLYRVIATDKDEGPNAEISYSI--EDGNE----HG-KFFIEPKTGVVSSKRF 1314 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD--VNDNEPV-FKQQLYTANIMEDAL 595 +L++ A D G P S TT + I + EP+ F++ +T +ME Sbjct: 1315 SAAGEYD--ILSIKAVDNGRPQKSSTTRLHIEWISKPKQSLEPISFEESFFTFTVMESDP 1372 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655 V + + + L +++ + F +D +G I K LD E + ++L Sbjct: 1373 VAHMIGVISVEPPGIPL----WFDI-TGGNYDSHFDVDKGTGTIIVAKPLDAEQKSNYNL 1427 Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 A DG T + V IK+ D ND P F + I E++ T I +I A D D Sbjct: 1428 TVEATDGTT---TILTQVFIKVIDTNDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQD 1484 Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE--SPRKKYELVIRAASPP 773 E N ++ Y+++ D S + R L T LD+E SP +V P Sbjct: 1485 E-KNKLI-YTLQSSRDPLSLK-KFRLDPATGSLYTSEKLDHEAVSPAHLTVMVRDQDVPV 1541 Query: 774 LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRI 831 N R+ + V+D ND+AP Y+ +V A D D ++ Y I Sbjct: 1542 KRNFARIVVNVSDTNDHAPWFTASSYKGRVYESAAVGSVVLQVTALDKDKGKNAEVLYSI 1601 Query: 832 LSGNNANL---ILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 SGN N+ +++ GS+ + +L+ + + V TD Sbjct: 1602 ESGNIGNIGNSFMIDPVLGSIKTAKELDRSNQAEYDLMVKATD 1644 Score = 272 bits (666), Expect = 1e-70 Identities = 213/716 (29%), Positives = 326/716 (45%), Gaps = 46/716 (6%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F +D +G ++ LD E+ + Y + V+ATD + + + + + +ID ND+ PQ Sbjct: 1402 FDVDKGTGTIIVAKPLDAEQKSNYNLTVEATDGTTTILTQ------VFIKVIDTNDHRPQ 1455 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQM---QFSIDSLS 206 FS Y V + ED + I +I A D D + + Y + + +F +D + Sbjct: 1456 FSTSKYEVVIPEDTAPETE--ILQISAVDQD--EKNKLIYTLQSSRDPLSLKKFRLDPAT 1511 Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266 G + + LD+E V L + +D P + N ++++N+ D ND+AP F S ++ V Sbjct: 1512 GSLYTSEKLDHEAVSPAHLTVMVRDQDVPVKRNFARIVVNVSDTNDHAPWFTASSYKGRV 1571 Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326 E+ +G +++V A D D+G NAE+ Y++ + GN+ IDP G + T+ +LDR Sbjct: 1572 YESAAVGSVVLQVTALDKDKGKNAEVLYSI-ESGNIGNIGNSFMIDPVLGSIKTAKELDR 1630 Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386 QA+Y L+V ATD G PP S + F +Y VEL+E G+ V Sbjct: 1631 SNQAEYDLMVKATDKGSPPMSEITSVRIFVTIADNASPKFTSKEYSVELSETVSIGSFVG 1690 Query: 387 TLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446 +T A + + YEI GNT F I + G I + LDF+ Y L + T+ Sbjct: 1691 MVT---AHSQSSVVYEIKDGNTGDAFDINPHS--GTIITQKALDFETLPIYTLIIQGTNM 1745 Query: 447 GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV-------LVVSATDSDVG 499 G S V +++ D N+ APVF A YT + E A I + V LV+ A D+D Sbjct: 1746 AGLSTNTTVLVHLQDENDNAPVFMQAEYTGLISESASINSVVLTDRNVPLVIRAADADKD 1805 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 NA + Y + E H F I+ TGAI T LD E S + TV D G P Sbjct: 1806 SNALLVYHIV-----EPSVH--TYFAIDSSTGAIHTVLSLDYEETSIFHFTVQVHDMGTP 1858 Query: 560 SL--SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617 L +V + V+D+ND PVF + LY A+++ G V V ATDAD ++ Sbjct: 1859 RLFAEYAANVTVHVIDINDCPPVFAKPLYEASLLLPTYKGVKVITVNATDADSSAFSQLI 1918 Query: 618 YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 Y + + E F +D +G + S ++L A DG +S V I + Sbjct: 1919 YSITEGNIGE-KFSMDYKTGALTVQNTTQLRS--RYELTVRASDGRFAGLTS---VKINV 1972 Query: 678 EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL 737 ++ +S F D + + ENS T+ I A N + Y I D F + Sbjct: 1973 KESKESHLKFTQDVYSAVVKENSTEAETLAVITA--IGSPINEPLFYHILNPD--RRFKI 2028 Query: 738 ETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPV 793 +R + T D + + VI P V V+++V D NDNAPV Sbjct: 2029 -SRTSGVLSTTGTPFDREQQEAFDVVVEVIEEHKPSAVAHVVVKVIVEDQNDNAPV 2083 Score = 254 bits (621), Expect = 3e-65 Identities = 229/798 (28%), Positives = 371/798 (46%), Gaps = 68/798 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ V D ND++PVF Y A V+ G + + A D+D G+N EV Y ++ Sbjct: 2071 KVIVEDQNDNAPVFVNLPYYAVVKVDTEVGHVIRYVTAVDRDSGRNGEVHYYLK------ 2124 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + ++ F +D +L++E Y V V A D +P Sbjct: 2125 -EHHEHFQIGPLGEISLKKQFELD----------TLNKE----YLVTVVAKDGGNPA--- 2166 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S+ + + ++ N P F + Y+ + E I V +PV+ ++A + + Y Sbjct: 2167 FSAEVIVPITVM--NKAMPVFEKPFYSAEIAESIQV-HSPVV-HVQANSPE---GLKVFY 2219 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 +I G+ QF+I+ +G ++++ LD+E +Y+L IRA D + + + +I + D Sbjct: 2220 SITDGDPFSQFTINFNTGVINVIAPLDFEAHPAYKLSIRATDSLTGAHAEVFVDII-VDD 2278 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 +NDN P F + ++SE IG S+V+V+A D+D N ++Y M +++ + D Sbjct: 2279 INDNPPVFAQQSYAVTLSEASVIGTSVVQVRATDSDSEPNRGISYQMFG-NHSKSHD-HF 2336 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 +D +G + LD E ++ + V A DGG P S+ F Sbjct: 2337 HVDSSTGLISLLRTLDYEQSRQHTIFVRAVDGGMPTLSSDVIVTVDVTDLNGNPPLFEQQ 2396 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 YE ++E P G V + A DAD + +L Y I GN F I S G +IT++ Sbjct: 2397 IYEARISEHAPHGHFVTCVKAYDADSSDIDKLQYSILSGNDHKHFVIDSATG--IITLSN 2454 Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 + Y L +S +D RS T V + + N ++P F Y + E+AP+ T Sbjct: 2455 LHRHALKPFYSLNLSVSDGVFRSST-QVHVTVIGGNLHSPAFLQNEYEVELAENAPLHTL 2513 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 V+ V TD D GI +TY + ++ + + +F IN + G I T + LDRET + Sbjct: 2514 VMEVKTTDGDSGIYGHVTYHIVNDFAKD-------RFYIN-ERGQIFTLEKLDRETPAEK 2565 Query: 548 LLTVT--ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 +++V A+D G T V + + D NDN P F+ Y NI A GTSV + A Sbjct: 2566 VISVRLMAKDAGGKVAFCT--VNVILTDDNDNAPQFRATKYEVNIGSSAAKGTSVVK-SA 2622 Query: 606 TDADVGLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 +DAD G N I Y ++ + + I+ SGVI T ++L A+D G+ Sbjct: 2623 SDADEGSNADITYAIEADSESVKENLEINKLSGVITTKESLIGLENEFFTFFVRAVDNGS 2682 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 P + S V+V++KI P F TF +SE+ P+GT I IRA E V++ Sbjct: 2683 PSKESVVLVYVKILPPEMQLPKFSEPFYTFTVSEDVPVGTEIDLIRA----EHSGTVLYS 2738 Query: 725 SIKGGD-DSN---SFSLETRQGSDKAELVTMVDLDYESPR-KKYELVIRAASPP--LWND 777 +KG +SN SF ++ + G K E LD+E+ + ++ ++ R + Sbjct: 2739 LVKGNTPESNRDESFVIDRQSGRLKLEK----SLDHETTKWYQFSILARCTQDDHEMVAS 2794 Query: 778 VRVEILVTDVNDNAPVMK 795 V V I V D NDN+PV + Sbjct: 2795 VDVSIQVKDANDNSPVFE 2812 Score = 216 bits (527), Expect = 8e-54 Identities = 215/787 (27%), Positives = 334/787 (42%), Gaps = 88/787 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASV-------REGASSGTTVLTLKATDQDIGKNAEVEYTIE 63 + +LD ND+ P F + Y+ + RE + + + ATD+D G NAE+ Y+IE Sbjct: 1233 VKILDENDNKPQFLQKFYKIRLPEREKPDRERNARREPLYRVIATDKDEGPNAEISYSIE 1292 Query: 64 LVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVL-VKATDQ 122 F I+ ++G + ++ Y +L +KA D Sbjct: 1293 -------------------DGNEHGKFFIEPKTGVVSSKRF---SAAGEYDILSIKAVDN 1330 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQ---FSEKTYTVSVDEDISVTDNPVIAKIKATDA 179 P + SST +H+ I + F E +T +V E +PV I Sbjct: 1331 GRP---QKSSTTRLHIEWISKPKQSLEPISFEESFFTFTVMES-----DPVAHMIGVISV 1382 Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239 + + + I GGN F +D +G + + K LD EQ +Y L + A DG + + Sbjct: 1383 EP-PGIPLWFDITGGNYDSHFDVDKGTGTIIVAKPLDAEQKSNYNLTVEATDG---TTTI 1438 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 TQ+ I + D ND+ P+F TS ++ + E+ I+++ A D DE +L YT+ Sbjct: 1439 LTQVFIKVIDTNDHRPQFSTSKYEVVIPEDTAPETEILQISAVDQDE--KNKLIYTLQSS 1496 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 ++ +DP +G +YTS +LD E + L V D P + A Sbjct: 1497 RDPLSLK-KFRLDPATGSLYTSEKLDHEAVSPAHLTVMVRDQDVPVKRNFARIVVNVSDT 1555 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRG-RFSITS 416 F Y+ + E G+ V+ +TA D D+ Y I GN S Sbjct: 1556 NDHAPWFTASSYKGRVYESAAVGSVVLQVTALDKDKGKNAEVLYSIESGNIGNIGNSFMI 1615 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPY 474 G I A+ LD + Y L V ATD G S+ V+I +T A+N +P F + Y Sbjct: 1616 DPVLGSIKTAKELDRSNQAEYDLMVKATDKGSPPMSEITSVRIFVTIADNASPKFTSKEY 1675 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 + + E IG+ V +V+A + + Y + + +A F INP +G I Sbjct: 1676 SVELSETVSIGSFVGMVTAHS-----QSSVVYEIKDGNTGDA-------FDINPHSGTII 1723 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 T K LD ET+ Y L + + + LS T V + + D NDN PVF Q YT I E A Sbjct: 1724 TQKALDFETLPIYTLIIQGTN--MAGLSTNTTVLVHLQDENDNAPVFMQAEYTGLISESA 1781 Query: 595 LVGTSVSQ-------VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647 + + V + A DAD N + Y + + F ID ++G I T +LD Sbjct: 1782 SINSVVLTDRNVPLVIRAADADKDSNALLVYHI-VEPSVHTYFAIDSSTGAIHTVLSLDY 1840 Query: 648 ESVATHDLKAVAIDGGTP----PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703 E + D GTP ++ V VH + DIND PPVF + + G Sbjct: 1841 EETSIFHFTVQVHDMGTPRLFAEYAANVTVH--VIDINDCPPVFAKPLYEASLLLPTYKG 1898 Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY 763 + + A D D + + YSI G+ FS++ + G+ + T + R +Y Sbjct: 1899 VKVITVNATDADSSAFSQLIYSITEGNIGEKFSMDYKTGALTVQNTTQL-------RSRY 1951 Query: 764 ELVIRAA 770 EL +RA+ Sbjct: 1952 ELTVRAS 1958 Score = 202 bits (492), Expect = 1e-49 Identities = 170/574 (29%), Positives = 275/574 (47%), Gaps = 43/574 (7%) Query: 103 ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162 A L+RE YT++VKA ++ + V R + V ++D ND P FS +Y+VS+ E+ Sbjct: 106 AILNREVKDHYTLIVKALEKNTNVEARTK----VRVQVLDTNDLRPLFSPTSYSVSLPEN 161 Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222 ++ + IA++ ATDAD+G N Y+ T M F+I SG + L LDY + + Sbjct: 162 TAIRTS--IARVSATDADIGTNGEFYYSF-KDRTDM-FAIHPTSGVIVLTGRLDYLETKL 217 Query: 223 YRLVIRAQDGG-----SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277 Y + I A D G S S+ +L ++I N+ AP S + P Y+IV Sbjct: 218 YEMEILAADRGMKLYGSSGISSMAKLTVHIEQANECAPVITAVTLSPSELDRDP-AYAIV 276 Query: 278 RVQAYDADEGVNAEL-TYTMTDKDYTGNVDLPITIDPRSGW-VYTSGQLDRETQA-KYQL 334 V D D+G N ++ + ++ D + + V G +D ++ Y L Sbjct: 277 TVD--DCDQGANGDIASLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGDIDWDSHPFGYNL 334 Query: 335 LVTATDGGDPPR-SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393 + A D G PP+ S+ F Y E++E PP TPVV + A A Sbjct: 335 TLQAKDKGTPPQFSSVKVIHVTSPQFKAGPVKFEKDVYRAEISEFAPPNTPVVMVKAIPA 394 Query: 394 DEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA 453 R ++ T G + +FS+ G LI++ +P+ +Q + L V+ +D R + Sbjct: 395 YSHLRYVFKRTPG--KAKFSLNYNTG--LISILEPVKRQQAAHFELEVTTSD---RKAST 447 Query: 454 MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513 V + + AN+ P F Y A+ E+ PIGTT++ +SA D D G N +TYS+++ Sbjct: 448 KVLVKVLGANSNPPEFTQTAYKAAFDENVPIGTTIMSLSAVDPDEGENGYVTYSIAN--- 504 Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSG-YLLTVTARDGGVPSLSDTTDV-EISV 571 +H F I+ TGA++T++ LD E M Y L + A D G+P + + I++ Sbjct: 505 ----LNH-VPFAIDHFTGAVSTSENLDYELMPRVYTLRIRASDWGLPYRREVEVLATITL 559 Query: 572 VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631 ++NDN P+F++ I D VG ++ V A DAD + Y+++ E F Sbjct: 560 NNLNDNTPLFEKINCEGTIPRDLGVGEQITTVSAIDADE--LQLVQYQIE-AGNELDLFS 616 Query: 632 IDPASGVIRTNKALD---RESVATHDLKAVAIDG 662 ++P SGV+ ++L V+ H L+ A DG Sbjct: 617 LNPNSGVLSLKRSLMDGLGAKVSFHSLRITATDG 650 Score = 139 bits (337), Expect = 9e-31 Identities = 152/587 (25%), Positives = 250/587 (42%), Gaps = 39/587 (6%) Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383 L+RE + Y L+V A + + T F P Y V L E+ T Sbjct: 108 LNREVKDHYTLIVKALEKNTNVEARTKVRVQVLDTNDLRPL-FSPTSYSVSLPENTAIRT 166 Query: 384 PVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443 + ++ATDAD + + + F+I +G +I + LD+ + + Y + + A Sbjct: 167 SIARVSATDADIGTNGEFYYSFKDRTDMFAIHPTSG--VIVLTGRLDYLETKLYEMEILA 224 Query: 444 TDSG-------GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496 D G G S A + ++I AN APV + S + P +V+ D Sbjct: 225 ADRGMKLYGSSGISSMAKLTVHIEQANECAPVITAVTLSPSELDRDP---AYAIVTVDDC 281 Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS-GYLLTVTARD 555 D G N I SLS + + + + +D ++ GY LT+ A+D Sbjct: 282 DQGANGDIA-SLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGDIDWDSHPFGYNLTLQAKD 340 Query: 556 GGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614 G P S + ++ F++ +Y A I E A T V V A A L Sbjct: 341 KGTPPQFSSVKVIHVTSPQFKAGPVKFEKDVYRAEISEFAPPNTPVVMVKAIPAYSHL-- 398 Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674 R ++ P + F ++ +G+I + + R+ A +L+ D ++ST ++ Sbjct: 399 RYVFKRTPG---KAKFSLNYNTGLISILEPVKRQQAAHFELEVTTSDR----KASTKVL- 450 Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734 +K+ N +PP F EN PIGTTI + A DPDEG N V YSI + Sbjct: 451 VKVLGANSNPPEFTQTAYKAAFDENVPIGTTIMSLSAVDPDEGENGYVTYSI-ANLNHVP 509 Query: 735 FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVT----DVNDN 790 F+++ G+ + T +LDYE + Y L IRA+ L VE+L T ++NDN Sbjct: 510 FAIDHFTGA----VSTSENLDYELMPRVYTLRIRASDWGLPYRREVEVLATITLNNLNDN 565 Query: 791 APVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMT 850 P+ + +D V A DAD +QY+I +GN +L LN +G ++ Sbjct: 566 TPLFEKINCEGTIPRDLGVGEQITTVSAIDADELQLVQYQIEAGNELDLFSLNPNSGVLS 625 Query: 851 LSPQLNTNV-PKLA--TMEVSVTDGVNEIKAMMQLSVRLITEEMLLN 894 L L + K++ ++ ++ TDG N + +++ + L+N Sbjct: 626 LKRSLMDGLGAKVSFHSLRITATDGEN-FATPLYINITVAASHKLVN 671 Score = 117 bits (282), Expect = 4e-24 Identities = 136/565 (24%), Positives = 238/565 (42%), Gaps = 68/565 (12%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ VLD ND P+F Y S+ E + T++ + ATD DIG N E Y+ + T Sbjct: 136 RVQVLDTNDLRPLFSPTSYSVSLPENTAIRTSIARVSATDADIGTNGEFYYSFKDRT--- 192 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV--S 127 D+F I SG ++ LD + Y + + A D+ + S Sbjct: 193 ------------------DMFAIHPTSGVIVLTGRLDYLETKLYEMEILAADRGMKLYGS 234 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVS-VDEDISVTDNPVIAKIKATDADVGANSA 186 +SS A + V+I N+ P + T + S +D D P A + D D GAN Sbjct: 235 SGISSMAKLTVHIEQANECAPVITAVTLSPSELDRD------PAYAIVTVDDCDQGANGD 288 Query: 187 I-RYAIIGGNTQMQF-SIDSLSGD----VSLVKTLDYE-QVRSYRLVIRAQDGGSPSRSN 239 I +I+ G+ QF ++ S G V + +D++ Y L ++A+D G+P + + Sbjct: 289 IASLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGDIDWDSHPFGYNLTLQAKDKGTPPQFS 348 Query: 240 TTQLL-INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 + +++ + +F +++ +SE P +V V+A A + L Y Sbjct: 349 SVKVIHVTSPQFKAGPVKFEKDVYRAEISEFAPPNTPVVMVKAIPA----YSHLRYVF-- 402 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358 K G +++ +G + + R+ A ++L VT +D R A+ Sbjct: 403 KRTPGKA--KFSLNYNTGLISILEPVKRQQAAHFELEVTTSD-----RKASTKVLVKVLG 455 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQN 418 F Y+ E+ P GT +++L+A D DE + + N + Sbjct: 456 ANSNPPEFTQTAYKAAFDENVPIGTTIMSLSAVDPDEGENGYVTYSIANL-NHVPFAIDH 514 Query: 419 GRGLITVAQPLDFK-QERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPY 474 G ++ ++ LD++ R Y L + A+D G R + I + + N+ P+FE Sbjct: 515 FTGAVSTSENLDYELMPRVYTLRIRASDWGLPYRREVEVLATITLNNLNDNTPLFEKINC 574 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 ++ D +G + VSA D+D Q+ E NE F +NP +G ++ Sbjct: 575 EGTIPRDLGVGEQITTVSAIDAD---ELQLV-QYQIEAGNEL-----DLFSLNPNSGVLS 625 Query: 535 TNK-LLD--RETMSGYLLTVTARDG 556 + L+D +S + L +TA DG Sbjct: 626 LKRSLMDGLGAKVSFHSLRITATDG 650 Score = 109 bits (261), Expect = 1e-21 Identities = 92/356 (25%), Positives = 164/356 (46%), Gaps = 23/356 (6%) Query: 113 YTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIA 172 Y + ++A D+ +P + SS IHV +F + Y + E + + PV+ Sbjct: 332 YNLTLQAKDKGTP--PQFSSVKVIHVTSPQFKAGPVKFEKDVYRAEISE-FAPPNTPVVM 388 Query: 173 KIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232 +KA + A S +RY + +FS++ +G +S+++ + +Q + L + D Sbjct: 389 -VKA----IPAYSHLRYVFKRTPGKAKFSLNYNTGLISILEPVKRQQAAHFELEVTTSD- 442 Query: 233 GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292 R +T++L+ + N N P F + ++ + ENVPIG +I+ + A D DEG N + Sbjct: 443 ----RKASTKVLVKVLGANSNPPEFTQTAYKAAFDENVPIGTTIMSLSAVDPDEGENGYV 498 Query: 293 TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDP-PRSATA 350 TY++ + ++ +P ID +G V TS LD E + Y L + A+D G P R Sbjct: 499 TYSIANLNH-----VPFAIDHFTGAVSTSENLDYELMPRVYTLRIRASDWGLPYRREVEV 553 Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG 410 F E + D G + T++A DADE + Y+I GN Sbjct: 554 LATITLNNLNDNTPLFEKINCEGTIPRDLGVGEQITTVSAIDADELQLVQYQIEAGNELD 613 Query: 411 RFSITSQNGRGLITVAQPL-DFKQERRYVLTVSATDSGGRSDTAMVQINITDANNY 465 FS+ + G++++ + L D + ++ T + G + + INIT A ++ Sbjct: 614 LFSLNPNS--GVLSLKRSLMDGLGAKVSFHSLRITATDGENFATPLYINITVAASH 667 Score = 100 bits (240), Expect = 5e-19 Identities = 95/357 (26%), Positives = 161/357 (45%), Gaps = 22/357 (6%) Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 +L+RE Y L V A + ++ T V + V+D ND P+F Y+ ++ E+ + Sbjct: 107 ILNREVKDHYTLIVKALEKNT-NVEARTKVRVQVLDTNDLRPLFSPTSYSVSLPENTAIR 165 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 TS+++V ATDAD+G NG +Y KDR + F I P SGVI LD ++++ Sbjct: 166 TSIARVSATDADIGTNGEFYYSF--KDRTD-MFAIHPTSGVIVLTGRLDYLETKLYEMEI 222 Query: 658 VAIDGGTPPQSSTVI-----VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 +A D G S+ I + + IE N+ PV + L+ + P + Sbjct: 223 LAADRGMKLYGSSGISSMAKLTVHIEQANECAPVITAVTLSPSELDRDP---AYAIVTVD 279 Query: 713 DPDEGPNA-VVHYSIKGGDDSNSF-SLETRQGSDKAELVTMVDLDYESPRKKYELVIRA- 769 D D+G N + SI GD F ++ + GS + ++ + D+D++S Y L ++A Sbjct: 280 DCDQGANGDIASLSIVAGDLLQQFRTVRSFPGSKEYKVKAIGDIDWDSHPFGYNLTLQAK 339 Query: 770 --ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCF--PVGPFGRVPAYDADVTD 825 +PP ++ V+V I VT A +K + ++ F P P V A A Sbjct: 340 DKGTPPQFSSVKV-IHVTSPQFKAGPVKFEKDVYRAEISEFAPPNTPVVMVKAIPA--YS 396 Query: 826 KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQL 882 L+Y LN TG +++ + +EV+ +D K ++++ Sbjct: 397 HLRYVFKRTPGKAKFSLNYNTGLISILEPVKRQQAAHFELEVTTSDRKASTKVLVKV 453 Score = 75.8 bits (178), Expect = 2e-11 Identities = 75/241 (31%), Positives = 111/241 (46%), Gaps = 34/241 (14%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VL N + P F Y+A+ E GTT+++L A D D G+N V Y+I L Sbjct: 451 VKVLGANSNPPEFTQTAYKAAFDENVPIGTTIMSLSAVDPDEGENGYVTYSIA-----NL 505 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSDR 129 N F ID +GA+ T +LD E + R YT+ ++A+D P Sbjct: 506 NHVP---------------FAIDHFTGAVSTSENLDYELMPRVYTLRIRASDWGLPYRRE 550 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + ATI +N + NDN P F + ++ D+ V + I + A DAD ++Y Sbjct: 551 VEVLATITLNNL--NDNTPLFEKINCEGTIPRDLGVGEQ--ITTVSAIDAD--ELQLVQY 604 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLD---YEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 I GN FS++ SG +SL ++L +V + L I A DG + T L IN Sbjct: 605 QIEAGNELDLFSLNPNSGVLSLKRSLMDGLGAKVSFHSLRITATDG----ENFATPLYIN 660 Query: 247 I 247 I Sbjct: 661 I 661 Score = 52.8 bits (121), Expect = 1e-04 Identities = 97/415 (23%), Positives = 146/415 (35%), Gaps = 58/415 (13%) Query: 1310 CPEKRSRCSSAPCYNGAEC-SDLW-DTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFN 1367 CP C PC G+EC SD W + + C C G G+ C S+ G+ + + Sbjct: 3789 CPPVHHGCEDDPCPEGSECVSDPWEEKHTCVCPSGRFGQ-CPGSSS--MTLTGNSYVKYR 3845 Query: 1368 PLLRPIQLPWLNALSIRTRQRDAFVM--------SIQLKSGLLHYSYN-GE---TMYLPM 1415 +L + +RT A VM +++ G L Y ++ G + + Sbjct: 3846 LTENENKLEMKLTMRLRTYSTHAVVMYARGTDYSILEIHHGRLQYKFDCGSGPGIVSVQS 3905 Query: 1416 ATLSDGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGL- 1474 ++DG WH + ++ G + +D + T + GG G Sbjct: 3906 IQVNDGQWHAVALEVNGNYARLVLDQ-VHTASGTAPGTLKTLNLDNYVFFGGHIRQQGTR 3964 Query: 1475 --LASDVG-FFEGCIQDVRIGTAQSLLN-RPT----VRE--NVRDGC--QSRADCMLSIC 1522 + VG F GC+ + + + LN +P + E +V GC + DC + C Sbjct: 3965 HGRSPQVGNGFRGCMDSIYLNGQELPLNSKPRSYAHIEESVDVSPGCFLTATEDCASNPC 4024 Query: 1523 PPYSKCVTS-WDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGYSCACEP 1577 C S C C A +G C V+ C PC CV D G+ C C Sbjct: 4025 QNGGVCNPSPAGGYYCKCSALYIGTHCEISVNPCSSNPCLYGGTCVVDN--GGFVCQCRG 4082 Query: 1578 GYTLTTSGCIESGKEE-CPGGWWGGSACGPCACDVTRGYH-PHCNKENGKCHCKENHYKP 1635 YT K+E C G + C G+ C + +C Sbjct: 4083 LYTGQRCQLSPYCKDEPCKNGGTCFDSLDGAVCQCDSGFRGERCQSDIDEC--------- 4133 Query: 1636 EGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRAC-DACANAYAEVTPNSG 1689 G PC + A EN+ + C+C GR C DA N Y N G Sbjct: 4134 SGN----PC-LHGALCENTH---GSYHCNCSHEYRGRHCEDAAPNQYVSTPWNIG 4180 >UniRef50_Q9VW71 Cluster: Putative fat-like cadherin-related tumor suppressor homolog precursor; n=3; Diptera|Rep: Putative fat-like cadherin-related tumor suppressor homolog precursor - Drosophila melanogaster (Fruit fly) Length = 4705 Score = 443 bits (1092), Expect = e-122 Identities = 355/1244 (28%), Positives = 584/1244 (46%), Gaps = 107/1244 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+V D ND+ P F+ Y ASV E + +++ + ATD D G N ++ Y +E +DT Sbjct: 2864 IDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYYLE---SDTE 2920 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N +Q++F ID SG + SLDRE + Y V A D P D Sbjct: 2921 N--------------IQNIFDIDIYSGWITLLTSLDREVQSEYNFKVIAADNGHPKHD-- 2964 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + + + I+D NDN P F +SV E+ V+ + D D+ + + Sbjct: 2965 -AKVPVTIKIVDYNDNAPVFKLPIEGLSVFEN--ALPGTVLINLLLIDPDI-EKQEMDFF 3020 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I+ G+ Q QF I SG++ + K LD EQ+ Y L I A DG +++N I+++D+ Sbjct: 3021 IVSGDKQAQFQIGK-SGELFIAKPLDREQLMFYNLSIIATDGKFTAKANVE---IDVKDI 3076 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P + S +E++ IG ++V V+A D D ++L + ++ K G D + Sbjct: 3077 NDNTPYCLKPRYHISTNESISIGTTLVEVKAIDFD--FQSKLRFYLSGK---GADDF--S 3129 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I SG + + LDRET KY+L+ DG D + + F Q Sbjct: 3130 IGKESGILKVASALDRETTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIFSMAQ 3189 Query: 371 YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 Y V + ED T + + A D D + ++ Y + G N F I+ G +I + + Sbjct: 3190 YRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGEN-HDYFKISKSTG--IIRLHKS 3246 Query: 429 LDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD + + LTV A D G A V +NI D N+ P F Y+ + E+A GT Sbjct: 3247 LDRETISLFNLTVKAEDCGVPKLHSIATVAVNILDINDNPPEFSMRQYSCKILENATHGT 3306 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 V V AT D+G+NA I Y + S NE +F ++ TG + N LD E Sbjct: 3307 EVCKVYATSIDIGVNADIHYFIMS--GNE-----QGKFKMDSTTGDLVLNATLDYEMSKF 3359 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y LT+ A DGG P LS+ V IS++D+NDN P F Q LY N+ ED VG+ + V AT Sbjct: 3360 YFLTIQAIDGGTPPLSNNAYVNISILDINDNSPTFLQNLYRINVNEDIFVGSKILDVKAT 3419 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D D +NG + Y ++ D G F IDP +G I ++ LDRE+++ + L+ A D G P Sbjct: 3420 DEDSDVNGLVTYNIERGDNI-GQFSIDPKNGTISVSRPLDRETISHYTLEIQACDQGDPQ 3478 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH-YS 725 + ++V ++I I D ND+ P+F S + + EN +G + D DE PN + + Sbjct: 3479 RCNSVPININILDTNDNAPIFSSSNYSVVLQENRLLGYVFLTFKISDADETPNTTPYTFD 3538 Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVT 785 I+ G++ F LE + GS + + + + + V +PPL++D V + + Sbjct: 3539 IRSGNEGGLFRLE-QDGSLRT--ASRFNHNLQDEFVIQVRVFDNGTPPLYSDAWVVVKII 3595 Query: 786 DVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSG-----NNANLI 840 + + P++ ++ N+++D F G+V A D D D+L + ++SG ++ L Sbjct: 3596 EESQYPPIVTPLEVTINSFEDDFSGAFIGKVHASDQDKYDELNFSLVSGPDDMYQSSKLF 3655 Query: 841 LLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRL 900 ++ TG + L+ + KL VSV+DG + ++++++V L+T +ML S+ +R Sbjct: 3656 NISNNTGKIYAISNLDIGLYKL---NVSVSDGKFHVFSIVKINVELVTNDMLKESVVIRF 3712 Query: 901 NDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEV 960 ++A +FL F+ + I+ C ++++ + ++Q D + AR D+++ Sbjct: 3713 RRISASEFLLSHRKTFMRSIRNIMRCRQKDVILITLQSDYQKASQHAVGNRRARSIDSDL 3772 Query: 961 GVA---------GDPSPHYSPTHLRERVYLHRTTL---ARLATVQVLP----FDDNICVH 1004 V D ++ +R+ + + + L VLP + N CVH Sbjct: 3773 NVVFAVRKQQIIPDSDEFFTSDEIRQTLIDKKNEIENETNLVVEDVLPSTCQSNKNDCVH 3832 Query: 1005 EPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASC 1064 C ++ L +LK + F + S PV TC C GF G +C+ + S Sbjct: 3833 GEC---KQILQILKNNVTTTFTDVISFAAPSYIPVN--TCVCRPGFDGKHCKETVNACST 3887 Query: 1065 EVDGDGSICR-SGS----QCVARRE-GGILCQGCSIDAAYTTAVCEL-RARSFPVSSFLT 1117 + IC SGS QCV + G C+ S + + L A SF S+ Sbjct: 3888 DPCSPQRICMPSGSALGYQCVCPKGFSGTYCERKSSKCSNESCDMGLFTAVSFGGKSYAH 3947 Query: 1118 FPGLKRRHRIHLK------LKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRGGGPG 1171 + K + + L+ L+ T +G LLY + + D+ LE+++ Sbjct: 3948 YKINKVKAKFTLENGFSYSLQIRTVQQTGTLLY---ASGKVDYNILEIING--------A 3996 Query: 1172 LRFSFSLGGGKSEITVEG-NVGDGSWHTVEIEYFNRTITMILDD 1214 +++ F LG G+ I+V N+ DG WH + +E + +++D+ Sbjct: 3997 VQYRFDLGSGEGVISVSSINISDGEWHQISLERSLNSAKVMVDN 4040 Score = 355 bits (874), Expect = 8e-96 Identities = 274/877 (31%), Positives = 414/877 (47%), Gaps = 48/877 (5%) Query: 87 QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146 QD F I SG L+ + +LDRE+ + ++V A PV + A + +++ D+NDN Sbjct: 2817 QDHFMISD-SGELILQQTLDREQQESHNLIVVAETSTVPV---FFAYADVLIDVRDENDN 2872 Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ--FSIDS 204 YP+F Y+ SV E+ + + K+ ATDAD G N IRY + +Q F ID Sbjct: 2873 YPKFDNTFYSASVAENSEKVIS--LVKVSATDADTGPNGDIRYYLESDTENIQNIFDIDI 2930 Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 SG ++L+ +LD E Y + A D G P + I I D NDNAP F + Sbjct: 2931 YSGWITLLTSLDREVQSEYNFKVIAADNGHPKHDAKVPVTIKIVDYNDNAPVFKLPIEGL 2990 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 SV EN G ++ + D D E+ + + D + +SG ++ + L Sbjct: 2991 SVFENALPGTVLINLLLIDPDIE-KQEMDFFIVSGDKQAQFQIG-----KSGELFIAKPL 3044 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 DRE Y L + ATDG +A A + +Y + E GT Sbjct: 3045 DREQLMFYNLSIIATDG---KFTAKANVEIDVKDINDNTPYCLKPRYHISTNESISIGTT 3101 Query: 385 VVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444 +V + A D D ++L + ++G FSI ++G ++ VA LD + +Y L Sbjct: 3102 LVEVKAIDFDFQSKLRFYLSGKGADD-FSIGKESG--ILKVASALDRETTPKYKLVAHVQ 3158 Query: 445 DSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502 D + +I IT D N+ P+F A Y SV EDA + T + V A D D G+N Sbjct: 3159 DGKDFTQECFSEIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNR 3218 Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 QI YSL E +HD F I+ TG I +K LDRET+S + LTV A D GVP L Sbjct: 3219 QIKYSLMGE-------NHDY-FKISKSTGIIRLHKSLDRETISLFNLTVKAEDCGVPKLH 3270 Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP 622 V ++++D+NDN P F + Y+ I+E+A GT V +V AT D+G+N IHY + Sbjct: 3271 SIATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYATSIDIGVNADIHYFI-M 3329 Query: 623 KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND 682 E+G F +D +G + N LD E + L AIDGGTPP S+ V+I I DIND Sbjct: 3330 SGNEQGKFKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDGGTPPLSNNAYVNISILDIND 3389 Query: 683 SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 + P F + ++E+ +G+ I +++A D D N +V Y+I+ GD+ FS++ + G Sbjct: 3390 NSPTFLQNLYRINVNEDIFVGSKILDVKATDEDSDVNGLVTYNIERGDNIGQFSIDPKNG 3449 Query: 743 SDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVM--KDF 797 + + LD E+ Y L I+A P N V + I + D NDNAP+ ++ Sbjct: 3450 T----ISVSRPLDRET-ISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFSSSNY 3504 Query: 798 QIIF-NNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 ++ N + F A + T + I SGN L L E GS+ + + N Sbjct: 3505 SVVLQENRLLGYVFLTFKISDADETPNTTPYTFDIRSGNEGGLFRL-EQDGSLRTASRFN 3563 Query: 857 TNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGF 915 N+ ++V V D G + + + V++I E +T ++T F G Sbjct: 3564 HNLQDEFVIQVRVFDNGTPPLYSDAWVVVKIIEESQYPPIVTPL--EVTINSFEDDFSGA 3621 Query: 916 FIDGLAAIIPCPKE--NIYIFSVQDDTDVTGNILNVS 950 FI + A + N + S DD + + N+S Sbjct: 3622 FIGKVHASDQDKYDELNFSLVSGPDDMYQSSKLFNIS 3658 Score = 321 bits (788), Expect = 2e-85 Identities = 255/858 (29%), Positives = 410/858 (47%), Gaps = 70/858 (8%) Query: 17 NDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAX 76 N H P F E S+ E G TV ++A D+D+G N ++ + I D+ Sbjct: 763 NVHRPEFVNFPQELSINESVQLGETVAWIEAKDRDLGYNGKLVFAISDGDYDS------- 815 Query: 77 XXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATI 136 VFRID G L LDRE+ Y + + D +P S++ + Sbjct: 816 ------------VFRIDPDRGELQIIGYLDRERQNEYVLNITVYDLGNPTK---STSKML 860 Query: 137 HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNT 196 + I+D NDN P + T + E + V+ + ATDAD G N+ + YA+ Sbjct: 861 PITILDVNDNRPVIQKTLATFRLTESARI--GTVVHCLHATDADSGINAQVTYAL--SVE 916 Query: 197 QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256 F++++ +G + L K LD E+ +Y L I A+DGGSP S+ + + + DVNDNAP Sbjct: 917 CSDFTVNATTGCLRLNKPLDREKQDNYALHITAKDGGSPVLSSEALVYVLVDDVNDNAPV 976 Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316 F + V E++P G + ++A D D G NAE+ +++ K+ T + +L ID +G Sbjct: 977 FGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSL--KEETQDEEL-FRIDKHTG 1033 Query: 317 WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG----QYE 372 + T G LD E + + L+V+A DGGDP S T+ F P YE Sbjct: 1034 AIRTQGYLDYENKQVHNLIVSAIDGGDP--SLTSDMSIVIMIIDVNENRFAPEFDDFVYE 1091 Query: 373 VELAEDEPPGTPVVTLTATDADE---DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 ++ E++P GT V+ +TA D D ++++ Y ITGG+ G F++ N +G IT L Sbjct: 1092 GKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFAV---NDQGSITSLSQL 1148 Query: 430 DFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 D + + Y LT+ A D S+ V I + + N+ P+ + Y +V E + Sbjct: 1149 DAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVENVE 1208 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKLLDRETMSG 546 ++ + A D D+ ITY++ +S V + F I+ +TG I TT + LDRE + Sbjct: 1209 IITLKAFDPDIDPTQTITYNI---VSGNLVGY----FEIDSKTGVIKTTERKLDRENQAE 1261 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 ++L V D G P LS T+ + +SV+D+NDN P F Q++Y + A V S+ QV A Sbjct: 1262 HILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQVPSSATVNQSIFQVHAI 1321 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D+D G NGRI Y + + + F ID G I K LD ++ +KA D G P Sbjct: 1322 DSDSGENGRITYSI-KSGKGKNKFRIDSQRGHIHIAKPLDSDNEFEIHIKAE--DNGIPK 1378 Query: 667 QSSTVIVHIKIEDIN----DSPPVFESDCLTFY-ISENSPIGTTIGEIRAHDPDEGPNAV 721 +S T V+I + +N ++P + ++EN G + +I A D D N Sbjct: 1379 KSQTARVNIVVVPVNPNSQNAPLIVRKTSENVVDLTENDKPGFLVTQILAVDDD---NDQ 1435 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781 + Y+I G+D N+F + G D ++ LDYE+ ++ Y L I + Sbjct: 1436 LWYNISNGNDDNTFYI----GQDNGNILLSKYLDYET-QQSYNLTISVTDGTFTAFTNLL 1490 Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNAN--- 838 + V D+NDN P N ++ ++ A D D KL Y + + + + Sbjct: 1491 VQVIDINDNPPQFAKDVYHVNISENIEEESVIMQLHATDRDEDKKLFYHLHATQDPSSLA 1550 Query: 839 LILLNETTGSMTLSPQLN 856 L ++ +G++ ++ +L+ Sbjct: 1551 LFRIDSISGNVIVTQRLD 1568 Score = 308 bits (755), Expect = 2e-81 Identities = 246/873 (28%), Positives = 410/873 (46%), Gaps = 69/873 (7%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 D ND++PVF +Q+Y VRE GT + ++A D+DIG NAE++++++ T D Sbjct: 969 DVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSLKEETQD------ 1022 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134 +++FRID +GA+ T+ LD E + ++V A D P L+S Sbjct: 1023 ------------EELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDP---SLTSDM 1067 Query: 135 TIHVNIIDDNDN--YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSAIRYAI 191 +I + IID N+N P+F + Y V E + + + A D D V NS I Y+I Sbjct: 1068 SIVIMIIDVNENRFAPEFDDFVYEGKVKE--NKPKGTFVMNVTARDMDTVDLNSKITYSI 1125 Query: 192 IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251 GG+ F+++ G ++ + LD E Y L + AQD SN ++ I + + N Sbjct: 1126 TGGDGLGIFAVND-QGSITSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENEN 1184 Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311 DN P ++ +V+E I+ ++A+D D +TY + +GN+ I Sbjct: 1185 DNIPLTDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTITYNIV----SGNLVGYFEI 1240 Query: 312 DPRSGWVYTS-GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 D ++G + T+ +LDRE QA++ L V +D G P S+T+ F Sbjct: 1241 DSKTGVIKTTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRV 1300 Query: 371 YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 Y+V++ + + A D+D E+ R+ Y I G + +F I SQ RG I +A+P Sbjct: 1301 YKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIKSGKGKNKFRIDSQ--RGHIHIAKP 1358 Query: 429 LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDAN---NYAP--VFENAPYTASVFED 481 LD + + + + A D+G +S TA V I + N AP V + + + E+ Sbjct: 1359 LD--SDNEFEIHIKAEDNGIPKKSQTARVNIVVVPVNPNSQNAPLIVRKTSENVVDLTEN 1416 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 G V + A D D N Q+ Y++S+ + D F I G I +K LD Sbjct: 1417 DKPGFLVTQILAVDDD---NDQLWYNISN-------GNDDNTFYIGQDNGNILLSKYLDY 1466 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 ET Y LT++ DG + + T++ + V+D+NDN P F + +Y NI E+ + + Sbjct: 1467 ETQQSYNLTISVTDG---TFTAFTNLLVQVIDINDNPPQFAKDVYHVNISENIEEESVIM 1523 Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 Q+ ATD D H F ID SG + + LD E A H L D Sbjct: 1524 QLHATDRDEDKKLFYHLHATQDPSSLALFRIDSISGNVIVTQRLDFEKTAQHILIVFVKD 1583 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 G P + + + + + D ND P F + + + E++ IG+ + E+RA D D G NA Sbjct: 1584 QGAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVPESAAIGSKLAEVRAIDRDSGHNAE 1643 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDV 778 + YSI G+ + F ++ G ++T+ + ++Y L ++A +PPL + + Sbjct: 1644 IQYSIITGNVGSVFEIDPTFG-----IITLAGNLNINKIQEYMLQVKAVDLGNPPLSSQI 1698 Query: 779 RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNAN 838 V I+VT ++ P I +++ P+G F V A + + + I+SGN Sbjct: 1699 PVHIIVTMSENDPPKFPTNNIAIEIFEN-LPIGTF--VTQVTARSSSSIFFNIISGNINE 1755 Query: 839 LILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 +N +TG + ++ ++ K+ + V T+ Sbjct: 1756 SFRINPSTGVIVINGNIDYESIKVFNLTVKGTN 1788 Score = 302 bits (742), Expect = 7e-80 Identities = 269/931 (28%), Positives = 428/931 (45%), Gaps = 73/931 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I +LD ND+ PV + + E A GT V L ATD D G NA+V Y + + +D Sbjct: 862 ITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHATDADSGINAQVTYALSVECSD-- 919 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F ++ +G L LDREK Y + + A D SPV L Sbjct: 920 -------------------FTVNATTGCLRLNKPLDREKQDNYALHITAKDGGSPV---L 957 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SS A ++V + D NDN P F + Y V ED+ V+A I+A D D+G N+ I+++ Sbjct: 958 SSEALVYVLVDDVNDNAPVFGVQEYIFKVREDL--PRGTVLAVIEAVDEDIGPNAEIQFS 1015 Query: 191 IIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 + TQ + F ID +G + LDYE + + L++ A DGG PS ++ ++I I Sbjct: 1016 -LKEETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMII 1074 Query: 249 DVNDN--APRFYTSLFQESVSENVPIGYSIVRVQAYDADE-GVNAELTYTMTDKDYTGNV 305 DVN+N AP F +++ V EN P G ++ V A D D +N+++TY++T D G Sbjct: 1075 DVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLG-- 1132 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 I G + + QLD ET+ Y L + A D P S Sbjct: 1133 ---IFAVNDQGSITSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPL 1189 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLI 423 Y V + E ++TL A D D D + Y I GN G F I S+ G + Sbjct: 1190 TDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTG-VIK 1248 Query: 424 TVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFED 481 T + LD + + ++L V+ +D+G S T+ + +++ D N+ +P F+ Y V Sbjct: 1249 TTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQVPSS 1308 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 A + ++ V A DSD G N +ITYS+ S +F I+ Q G I K LD Sbjct: 1309 ATVNQSIFQVHAIDSDSGENGRITYSIKS-------GKGKNKFRIDSQRGHIHIAKPLDS 1361 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP-----VFKQQLYTANIMEDALV 596 + + + + + A D G+P S T V I VV VN N V K ++ E+ Sbjct: 1362 D--NEFEIHIKAEDNGIPKKSQTARVNIVVVPVNPNSQNAPLIVRKTSENVVDLTENDKP 1419 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 G V+Q+ A D D N ++ Y + ++ +F I +G I +K LD E+ +++L Sbjct: 1420 GFLVTQILAVDDD---NDQLWYNIS-NGNDDNTFYIGQDNGNILLSKYLDYETQQSYNL- 1474 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 +++ GT + ++V ++ DIND+PP F D ISEN + I ++ A D DE Sbjct: 1475 TISVTDGTFTAFTNLLV--QVIDINDNPPQFAKDVYHVNISENIEEESVIMQLHATDRDE 1532 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI--RAASPPL 774 + + Y + D +S +L R S ++ LD+E + +V +P Sbjct: 1533 --DKKLFYHLHATQDPSSLAL-FRIDSISGNVIVTQRLDFEKTAQHILIVFVKDQGAPGK 1589 Query: 775 WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADV--TDKLQYRI 831 N ++ + V D ND+ P +II + + +G V A D D ++QY I Sbjct: 1590 RNYAKIIVNVHDHNDHHPEF-TAKIIQSKVPESAAIGSKLAEVRAIDRDSGHNAEIQYSI 1648 Query: 832 LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEM 891 ++GN ++ ++ T G +TL+ LN N + ++V D + Q+ V +I Sbjct: 1649 ITGNVGSVFEIDPTFGIITLAGNLNINKIQEYMLQVKAVD-LGNPPLSSQIPVHIIVTMS 1707 Query: 892 LLNSITVRLNDMTAEQFLSPLLGFFIDGLAA 922 + N++ E F + +G F+ + A Sbjct: 1708 ENDPPKFPTNNIAIEIFENLPIGTFVTQVTA 1738 Score = 299 bits (735), Expect = 5e-79 Identities = 229/759 (30%), Positives = 368/759 (48%), Gaps = 42/759 (5%) Query: 144 NDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSID 203 N + P+F +S++E + + + +A I+A D D+G N + +AI G+ F ID Sbjct: 763 NVHRPEFVNFPQELSINESVQLGET--VAWIEAKDRDLGYNGKLVFAISDGDYDSVFRID 820 Query: 204 SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263 G++ ++ LD E+ Y L I D G+P++S + L I I DVNDN P +L Sbjct: 821 PDRGELQIIGYLDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLAT 880 Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323 ++E+ IG + + A DAD G+NA++TY ++ + T++ +G + + Sbjct: 881 FRLTESARIGTVVHCLHATDADSGINAQVTYALSVE------CSDFTVNATTGCLRLNKP 934 Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383 LDRE Q Y L +TA DGG P S+ A F +Y ++ ED P GT Sbjct: 935 LDREKQDNYALHITAKDGGSPVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGT 994 Query: 384 PVVTLTATDADEDNRLHYEIT-GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 + + A D D + + T+ G I LD++ ++ + L VS Sbjct: 995 VLAVIEAVDEDIGPNAEIQFSLKEETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVS 1054 Query: 443 ATDSGGRSDTAMVQINI----TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD- 497 A D G S T+ + I I + N +AP F++ Y V E+ P GT V+ V+A D D Sbjct: 1055 AIDGGDPSLTSDMSIVIMIIDVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDT 1114 Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG 557 V +N++ITYS++ A +DQ G+IT+ LD ET + Y LT+ A+D Sbjct: 1115 VDLNSKITYSITGGDGLGIFAVNDQ--------GSITSLSQLDAETKNFYWLTLCAQDCA 1166 Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617 + LS+ +V I V + NDN P+ + +Y N+ E ++ + + A D D+ I Sbjct: 1167 IVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTIT 1226 Query: 618 YELDPKDREEGSFVIDPASGVIR-TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676 Y + G F ID +GVI+ T + LDRE+ A H L+ D G+P SST + + Sbjct: 1227 YNI-VSGNLVGYFEIDSKTGVIKTTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVS 1285 Query: 677 IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736 + DIND+ P F+ + ++ + +I ++ A D D G N + YSIK G N F Sbjct: 1286 VLDINDNSPEFDQRVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIKSGKGKNKFR 1345 Query: 737 LETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVN---DN 790 +++++G + +D D E +E+ I+A P RV I+V VN N Sbjct: 1346 IDSQRG--HIHIAKPLDSDNE-----FEIHIKAEDNGIPKKSQTARVNIVVVPVNPNSQN 1398 Query: 791 AP--VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGS 848 AP V K + + + ++ P ++ A D D D+L Y I +GN+ N + + G+ Sbjct: 1399 APLIVRKTSENVVDLTENDKPGFLVTQILAVDDD-NDQLWYNISNGNDDNTFYIGQDNGN 1457 Query: 849 MTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887 + LS L+ + + +SVTDG A L V++I Sbjct: 1458 ILLSKYLDYETQQSYNLTISVTDGT--FTAFTNLLVQVI 1494 Score = 281 bits (688), Expect = 3e-73 Identities = 257/904 (28%), Positives = 408/904 (45%), Gaps = 81/904 (8%) Query: 6 CIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELV 65 C+ I V + ND+ P+ + Y +V E + ++TLKA D DI + Y I V Sbjct: 1173 CVEVYIQVENENDNIPLTDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTITYNI--V 1230 Query: 66 TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLVKATDQAS 124 + + + F ID ++G + T LDRE A + + V +D S Sbjct: 1231 SGNLVG-----------------YFEIDSKTGVIKTTERKLDRENQAEHILEVAISDNGS 1273 Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184 PV LSST+ I V+++D NDN P+F ++ Y V V S T N I ++ A D+D G N Sbjct: 1274 PV---LSSTSRIVVSVLDINDNSPEFDQRVYKVQVPS--SATVNQSIFQVHAIDSDSGEN 1328 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 I Y+I G + +F IDS G + + K LD + + + I+A+D G P +S T ++ Sbjct: 1329 GRITYSIKSGKGKNKFRIDSQRGHIHIAKPLDSD--NEFEIHIKAEDNGIPKKSQTARVN 1386 Query: 245 INIRDVN---DNAPRFY--TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 I + VN NAP TS ++EN G+ + ++ A D D N +L Y +++ Sbjct: 1387 IVVVPVNPNSQNAPLIVRKTSENVVDLTENDKPGFLVTQILAVDDD---NDQLWYNISN- 1442 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 GN D I +G + S LD ETQ Y L ++ TDG +A Sbjct: 1443 ---GNDDNTFYIGQDNGNILLSKYLDYETQQSYNLTISVTDG---TFTAFTNLLVQVIDI 1496 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEI---TGGNTRGRFSITS 416 F Y V ++E+ + ++ L ATD DED +L Y + ++ F I S Sbjct: 1497 NDNPPQFAKDVYHVNISENIEEESVIMQLHATDRDEDKKLFYHLHATQDPSSLALFRIDS 1556 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPY 474 +G ++T Q LDF++ +++L V D G G+ + A + +N+ D N++ P F Sbjct: 1557 ISGNVIVT--QRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTAKII 1614 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 + V E A IG+ + V A D D G NA+I YS+ + F I+P G IT Sbjct: 1615 QSKVPESAAIGSKLAEVRAIDRDSGHNAEIQYSI-------ITGNVGSVFEIDPTFGIIT 1667 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 L+ + Y+L V A D G P LS V I V ++ P F I E+ Sbjct: 1668 LAGNLNINKIQEYMLQVKAVDLGNPPLSSQIPVHIIVTMSENDPPKFPTNNIAIEIFENL 1727 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654 +GT V+QV A + I + + + E SF I+P++GVI N +D ES+ + Sbjct: 1728 PIGTFVTQVTARS-----SSSIFFNIISGNINE-SFRINPSTGVIVINGNIDYESIKVFN 1781 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI----- 709 L + +I+HI D ND+ P F + + E++ IG+ + ++ Sbjct: 1782 LTVKGTNMAAESSCQNIIIHIL--DANDNIPYFVQNEYVGALPESAAIGSYVLKVHDSSK 1839 Query: 710 -----RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764 + D D G N +V Y I N F +++ G+ EL+ +D + + Sbjct: 1840 DHLTLQVKDADVGVNGMVEYHIVDDLAKNFFKIDSTTGA--IELLRQLDYETNAGYTFDV 1897 Query: 765 LVIRAASPPLWN--DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD 822 V P L + V I V +VND PV + ++ + F +V A DAD Sbjct: 1898 TVSDMGKPKLHSTTTAHVTIRVINVNDCPPVFNERELNVTLFLPTFENVFVRQVSAKDAD 1957 Query: 823 VTDKLQYRILSGNNANLILLNETTGSMTLS--PQLNTNVPKLATMEVSVTDGVNEIKAMM 880 D L++ I+ GN + + TG +T LN + + V +DG+ ++ Sbjct: 1958 -NDTLRFDIVDGNTNECFQIEKYTGIITTRNFEILNNENDRDYALHVRASDGIFSAILIV 2016 Query: 881 QLSV 884 ++ V Sbjct: 2017 KIKV 2020 Score = 262 bits (641), Expect = 1e-67 Identities = 235/830 (28%), Positives = 372/830 (44%), Gaps = 67/830 (8%) Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 + F I +G +L LD E Y + + TD ++ + V +ID NDN Sbjct: 1447 NTFYIGQDNGNILLSKYLDYETQQSYNLTISVTDGT------FTAFTNLLVQVIDINDNP 1500 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR-YAIIGGNTQMQFSIDSLS 206 PQF++ Y V++ E+I + VI ++ ATD D +A ++ F IDS+S Sbjct: 1501 PQFAKDVYHVNISENIE--EESVIMQLHATDRDEDKKLFYHLHATQDPSSLALFRIDSIS 1558 Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266 G+V + + LD+E+ + L++ +D G+P + N ++++N+ D ND+ P F + Q V Sbjct: 1559 GNVIVTQRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKV 1618 Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326 E+ IG + V+A D D G NAE+ Y++ TGNV IDP G + +G L+ Sbjct: 1619 PESAAIGSKLAEVRAIDRDSGHNAEIQYSI----ITGNVGSVFEIDPTFGIITLAGNLNI 1674 Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386 +Y L V A D G+PP S+ F +E+ E+ P GT V Sbjct: 1675 NKIQEYMLQVKAVDLGNPPLSSQIPVHIIVTMSENDPPKFPTNNIAIEIFENLPIGTFVT 1734 Query: 387 TLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446 +TA + + + + I GN F I G+I + +D++ + + LTV T+ Sbjct: 1735 QVTARSS---SSIFFNIISGNINESFRINPST--GVIVINGNIDYESIKVFNLTVKGTNM 1789 Query: 447 GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV----------SATDS 496 S + I+I DAN+ P F Y ++ E A IG+ VL V D+ Sbjct: 1790 AAESSCQNIIIHILDANDNIPYFVQNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVKDA 1849 Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556 DVG+N + Y + +++ F I+ TGAI + LD ET +GY VT D Sbjct: 1850 DVGVNGMVEYHIVDDLAKNF-------FKIDSTTGAIELLRQLDYETNAGYTFDVTVSDM 1902 Query: 557 GVPSLSDTT--DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614 G P L TT V I V++VND PVF ++ + V QV A DAD N Sbjct: 1903 GKPKLHSTTTAHVTIRVINVNDCPPVFNERELNVTLFLPTFENVFVRQVSAKDAD---ND 1959 Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTN--KALDRESVATHDLKAVAIDGGTPPQSSTVI 672 + +++ + E F I+ +G+I T + L+ E+ + L A DG S+ +I Sbjct: 1960 TLRFDIVDGNTNE-CFQIEKYTGIITTRNFEILNNENDRDYALHVRASDG---IFSAILI 2015 Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732 V IK+ DS F+ + F EN+ TIG + N V Y I + + Sbjct: 2016 VKIKVLSAIDSNFAFQRESYRFSAFENNTKVATIGLVNVIGNTLDEN--VEYRIL--NPT 2071 Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVR-----VEILV 784 F + G+ K T V D E + Y L + A S + ++VR ++I V Sbjct: 2072 QLFDIGISSGALK---TTGVIFDRE-VKDLYRLFVEAKSMLYDGMNSNVRRAVTSIDISV 2127 Query: 785 TDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADVTDKLQYRI-LSGNNANLILL 842 DVNDN P+ + D P G +V A D D + + R L N L L Sbjct: 2128 LDVNDNCPLFVNMPYYATVSID-DPKGTIIMQVKAIDLDSAENGEVRYELKKGNGELFKL 2186 Query: 843 NETTGSMTLSPQLNTNVPKLATMEVSVTDG-VNEIKAMMQLSVRLITEEM 891 + +G +++ + + + + V+ DG + + L V++I M Sbjct: 2187 DRKSGELSIKQHVEGH-NRNYELTVAAYDGAITPCSSEAPLQVKVIDRSM 2235 Score = 258 bits (633), Expect = 1e-66 Identities = 248/889 (27%), Positives = 384/889 (43%), Gaps = 81/889 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 ++++D ND P E Y ++ E AS GT +L + ATD D G NA++ Y IE + Sbjct: 2326 VSIMDVNDCYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQN- 2384 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP----- 125 N E +F ID G L + LD E++ + ++V D SP Sbjct: 2385 NSE---------------LFYIDVTDGNLYLKTPLDYEQIKYHHIVVNVKDHGSPSLSSR 2429 Query: 126 --------VSDRLSSTATIHVNII---DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKI 174 + R S I+ +II D NDN P F E +Y V ++ +A Sbjct: 2430 SNVFITGRILCRFISYKLIYDSIIPVKDLNDNAPCFVEPSYFTKV--SVAAVRGQFVALP 2487 Query: 175 KATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS 234 KA D D+ ++ Y I+ GN +SID L+G +SL L++ S L I DG Sbjct: 2488 KAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQNMLNFTDKSSTVLNISVSDG-- 2545 Query: 235 PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294 + +L I++ N +P F S ++ V EN+ G++I+ V+A D D G A L Y Sbjct: 2546 -VHTAYARLKISLLPENVYSPLFDQSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYY 2604 Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354 + ++ + ID +G + + DRE + +Y +L+ +DGG + A+ Sbjct: 2605 EIVSEE----MKKIFLIDQTTGVITSKVTFDREKKDEYVVLLKVSDGGG--KFGFASLKV 2658 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEIT-GGNTRGR 411 F+ +Y++ ++ ++T+ A D D ++ +H++I N + Sbjct: 2659 IVVDVNDNVPYFLLKEYKMVVSTTVEANQTILTVKAKDDDIVDNGSVHFQIVQKSNDKAV 2718 Query: 412 FSITSQNGR-GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINI----TDANNYA 466 + N + G I + Y V A+D G + V ++I TDAN Sbjct: 2719 KDVIEINEKTGDIVFKSKAESYGVNSYQFFVRASDRGEPQFHSEVPVSIEIIETDAN--I 2776 Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 P FE + + E P GT + + +G N +S+++ DQ + Sbjct: 2777 PTFEKSSVLLKIIESTPPGTVLTKLHM----IG-NYTFKFSIAA----------DQDHFM 2821 Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586 +G + + LDRE + L V A VP DV I V D NDN P F Y Sbjct: 2822 ISDSGELILQQTLDREQQESHNLIVVAETSTVPVFFAYADVLIDVRDENDNYPKFDNTFY 2881 Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELD-PKDREEGSFVIDPASGVIRTNKAL 645 +A++ E++ S+ +V ATDAD G NG I Y L+ + + F ID SG I +L Sbjct: 2882 SASVAENSEKVISLVKVSATDADTGPNGDIRYYLESDTENIQNIFDIDIYSGWITLLTSL 2941 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 DRE + ++ K +A D G P + V V IKI D ND+ PVF+ + EN+ GT Sbjct: 2942 DREVQSEYNFKVIAADNGHPKHDAKVPVTIKIVDYNDNAPVFKLPIEGLSVFENALPGTV 3001 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765 + + DPD + + I GD F + EL LD E Y L Sbjct: 3002 LINLLLIDPDI-EKQEMDFFIVSGDKQAQFQI-----GKSGELFIAKPLDREQ-LMFYNL 3054 Query: 766 VIRAASPPLWNDVRVEILVTDVNDNAP-VMKDFQIIFNNYKDCFPVG-PFGRVPAYDADV 823 I A VEI V D+NDN P +K I N + +G V A D D Sbjct: 3055 SIIATDGKFTAKANVEIDVKDINDNTPYCLKPRYHISTN--ESISIGTTLVEVKAIDFDF 3112 Query: 824 TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 KL++ LSG A+ + + +G + ++ L+ + V DG Sbjct: 3113 QSKLRF-YLSGKGADDFSIGKESGILKVASALDRETTPKYKLVAHVQDG 3160 Score = 249 bits (610), Expect = 7e-64 Identities = 236/879 (26%), Positives = 381/879 (43%), Gaps = 79/879 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I++L N +SP+F+ YEA V E G ++T+KA+D D G A + Y E+V+ + Sbjct: 2554 KISLLPENVYSPLFDQSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYY--EIVSEE- 2610 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 ++ +F ID +G + ++ + DREK Y VL+K +D Sbjct: 2611 ----------------MKKIFLIDQTTGVITSKVTFDREKKDEYVVLLKVSDGGGKF--- 2651 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 A++ V ++D NDN P F K Y + V +V N I +KA D D+ N ++ + Sbjct: 2652 --GFASLKVIVVDVNDNVPYFLLKEYKMVV--STTVEANQTILTVKAKDDDIVDNGSVHF 2707 Query: 190 AIIGGNTQMQ----FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 I+ + I+ +GD+ + V SY+ +RA D G P + + I Sbjct: 2708 QIVQKSNDKAVKDVIEINEKTGDIVFKSKAESYGVNSYQFFVRASDRGEPQFHSEVPVSI 2767 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM-TDKDYTGN 304 I + + N P F S + E+ P G + ++ N +++ D+D+ Sbjct: 2768 EIIETDANIPTFEKSSVLLKIIESTPPGTVLTKLHMIG-----NYTFKFSIAADQDHFMI 2822 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 D SG + LDRE Q + L+V A P A A Sbjct: 2823 SD--------SGELILQQTLDREQQESHNLIVVAETSTVPVFFAYADVLIDVRDENDNYP 2874 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADE----DNRLHYEITGGNTRGRFSITSQNGR 420 F Y +AE+ +V ++ATDAD D R + E N + F I + Sbjct: 2875 KFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYYLESDTENIQNIFDIDIYS-- 2932 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASV 478 G IT+ LD + + Y V A D+G A V I I D N+ APVF+ SV Sbjct: 2933 GWITLLTSLDREVQSEYNFKVIAADNGHPKHDAKVPVTIKIVDYNDNAPVFKLPIEGLSV 2992 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 FE+A GT ++ + D D+ + +S + QF I ++G + K Sbjct: 2993 FENALPGTVLINLLLIDPDIEKQEMDFFIVSGD--------KQAQFQIG-KSGELFIAKP 3043 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 LDRE + Y L++ A DG + +VEI V D+NDN P + Y + E +GT Sbjct: 3044 LDREQLMFYNLSIIATDG---KFTAKANVEIDVKDINDNTPYCLKPRYHISTNESISIGT 3100 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 ++ +V A D D ++ + L K ++ F I SG+++ ALDRE+ + L A Sbjct: 3101 TLVEVKAIDFD--FQSKLRFYLSGKGADD--FSIGKESGILKVASALDRETTPKYKLVAH 3156 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 DG Q + I + DIND+ P+F + E++ + T I ++ A D D G Sbjct: 3157 VQDGKDFTQECFSEIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGV 3216 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLW 775 N + YS+ G++ + F + G + LD E+ + L ++A P L Sbjct: 3217 NRQIKYSLM-GENHDYFKISKSTGIIRLH----KSLDRET-ISLFNLTVKAEDCGVPKLH 3270 Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA--YDADVTDKLQYRILS 833 + V + + D+NDN P Q ++ +V A D V + Y I+S Sbjct: 3271 SIATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYATSIDIGVNADIHYFIMS 3330 Query: 834 GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 GN ++ TTG + L+ L+ + K + + DG Sbjct: 3331 GNEQGKFKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDG 3369 Score = 247 bits (605), Expect = 3e-63 Identities = 229/841 (27%), Positives = 371/841 (44%), Gaps = 73/841 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 ++VLD ND+SP F+ + Y+ V A+ ++ + A D D G+N + Y+I+ Sbjct: 1284 VSVLDINDNSPEFDQRVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIK------- 1336 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 ++ FRID + G + LD + + + +KA D P + Sbjct: 1337 ------------SGKGKNKFRIDSQRGHIHIAKPLDSDN--EFEIHIKAEDNGIPKKSQT 1382 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP--VIAKIKATDADVGANSAIR 188 + + V + ++ N P KT VD ++ D P ++ +I A D D N + Sbjct: 1383 ARVNIVVVPVNPNSQNAPLIVRKTSENVVD--LTENDKPGFLVTQILAVDDD---NDQLW 1437 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y I GN F I +G++ L K LDYE +SY L I DG + + T LL+ + Sbjct: 1438 YNISNGNDDNTFYIGQDNGNILLSKYLDYETQQSYNLTISVTDG---TFTAFTNLLVQVI 1494 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D+NDN P+F ++ ++SEN+ I+++ A D DE + +L Y + ++ L Sbjct: 1495 DINDNPPQFAKDVYHVNISENIEEESVIMQLHATDRDE--DKKLFYHLHATQDPSSLAL- 1551 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 ID SG V + +LD E A++ L+V D G P + A F Sbjct: 1552 FRIDSISGNVIVTQRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTA 1611 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVA 426 + ++ E G+ + + A D D + + Y I GN F I G+IT+A Sbjct: 1612 KIIQSKVPESAAIGSKLAEVRAIDRDSGHNAEIQYSIITGNVGSVFEIDPT--FGIITLA 1669 Query: 427 QPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 L+ + + Y+L V A D G S V I +T + N P F +FE+ PI Sbjct: 1670 GNLNINKIQEYMLQVKAVDLGNPPLSSQIPVHIIVTMSENDPPKFPTNNIAIEIFENLPI 1729 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 GT V V+A S + I +++ S NE+ F INP TG I N +D E++ Sbjct: 1730 GTFVTQVTARSS-----SSIFFNIISGNINES-------FRINPSTGVIVINGNIDYESI 1777 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV- 603 + LTV + + + S ++ I ++D NDN P F Q Y + E A +G+ V +V Sbjct: 1778 KVFNLTV--KGTNMAAESSCQNIIIHILDANDNIPYFVQNEYVGALPESAAIGSYVLKVH 1835 Query: 604 ---------GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654 DADVG+NG + Y + D + F ID +G I + LD E+ A + Sbjct: 1836 DSSKDHLTLQVKDADVGVNGMVEYHI-VDDLAKNFFKIDSTTGAIELLRQLDYETNAGYT 1894 Query: 655 LKAVAIDGGTPPQSSTVIVH--IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 D G P ST H I++ ++ND PPVF L + + + ++ A Sbjct: 1895 FDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPPVFNERELNVTLFLPTFENVFVRQVSAK 1954 Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP 772 D D N + + I G+ + F +E G + L+ E+ R Y L +RA+ Sbjct: 1955 DAD---NDTLRFDIVDGNTNECFQIEKYTGIITTRNFEI--LNNENDR-DYALHVRASDG 2008 Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRIL 832 + V+I V D+ + F+ +++ V G V + + ++YRIL Sbjct: 2009 IFSAILIVKIKVLSAIDSNFAFQRESYRFSAFENNTKVATIGLVNVIGNTLDENVEYRIL 2068 Query: 833 S 833 + Sbjct: 2069 N 2069 Score = 241 bits (590), Expect = 2e-61 Identities = 239/885 (27%), Positives = 384/885 (43%), Gaps = 65/885 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND++P F Y V A G V KA D+DI +EY I V + L Sbjct: 2453 IPVKDLNDNAPCFVEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKI--VYGNEL 2510 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + ID +G + + L+ + + + +D RL Sbjct: 2511 Q-----------------TYSIDKLTGVISLQNMLNFTDKSSTVLNISVSDGVHTAYARL 2553 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 ++++ +N P F + TY V E++ N I +KA+D D G + + Y Sbjct: 2554 K------ISLLPENVYSPLFDQSTYEAQVPENLLHGHN--IITVKASDGDFGTYANLYYE 2605 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I+ + F ID +G ++ T D E+ Y ++++ DGG + L + + DV Sbjct: 2606 IVSEEMKKIFLIDQTTGVITSKVTFDREKKDEYVVLLKVSDGG--GKFGFASLKVIVVDV 2663 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F ++ VS V +I+ V+A D D N + + + K V I Sbjct: 2664 NDNVPYFLLKEYKMVVSTTVEANQTILTVKAKDDDIVDNGSVHFQIVQKSNDKAVKDVIE 2723 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I+ ++G + + + YQ V A+D G+P + F Sbjct: 2724 INEKTGDIVFKSKAESYGVNSYQFFVRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSS 2783 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 +++ E PPGT LT + + I + F I+ G + + Q LD Sbjct: 2784 VLLKIIESTPPGT---VLTKLHMIGNYTFKFSIAA--DQDHFMISDS---GELILQQTLD 2835 Query: 431 FKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 +Q+ + L V A S A V I++ D N+ P F+N Y+ASV E++ ++ Sbjct: 2836 REQQESHNLIVVAETSTVPVFFAYADVLIDVRDENDNYPKFDNTFYSASVAENSEKVISL 2895 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 + VSATD+D G N I Y L S+ N F I+ +G IT LDRE S Y Sbjct: 2896 VKVSATDADTGPNGDIRYYLESDTEN-----IQNIFDIDIYSGWITLLTSLDREVQSEYN 2950 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 V A D G P V I +VD NDN PVFK + ++ E+AL GT + + D Sbjct: 2951 FKVIAADNGHPKHDAKVPVTIKIVDYNDNAPVFKLPIEGLSVFENALPGTVLINLLLIDP 3010 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 D+ + + + D+ + F I SG + K LDRE + ++L +A DG ++ Sbjct: 3011 DIE-KQEMDFFIVSGDK-QAQFQIG-KSGELFIAKPLDREQLMFYNLSIIATDGKFTAKA 3067 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 + V I ++DIND+ P +E+ IGTT+ E++A D D + S KG Sbjct: 3068 N---VEIDVKDINDNTPYCLKPRYHISTNESISIGTTLVEVKAIDFDFQSKLRFYLSGKG 3124 Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVT-- 785 DD FS+ G + L LD E+ KY+LV + EI++T Sbjct: 3125 ADD---FSI----GKESGILKVASALDRET-TPKYKLVAHVQDGKDFTQECFSEIIITVN 3176 Query: 786 DVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLN 843 D+NDN P+ Q + +D +V A D D V +++Y ++ G N + ++ Sbjct: 3177 DINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLM-GENHDYFKIS 3235 Query: 844 ETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLI 887 ++TG + L L+ L + V D GV ++ ++ ++V ++ Sbjct: 3236 KSTGIIRLHKSLDRETISLFNLTVKAEDCGVPKLHSIATVAVNIL 3280 Score = 239 bits (586), Expect = 6e-61 Identities = 212/827 (25%), Positives = 364/827 (44%), Gaps = 57/827 (6%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F ID +G++ LD EK++ + V ++ATD S V + + V+I+D ND YP+ Sbjct: 2282 FEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLSGVY----AEVVLSVSIMDVNDCYPE 2337 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY---AIIGGNTQMQFSIDSLS 206 Y +++ E+ S I KI ATD D GAN+ + Y +I G N F ID Sbjct: 2338 IESDIYNLTIPENASFGTQ--ILKINATDNDSGANAKLSYYIESINGQNNSELFYIDVTD 2395 Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPS---RSN---TTQLL-------------INI 247 G++ L LDYEQ++ + +V+ +D GSPS RSN T ++L I + Sbjct: 2396 GNLYLKTPLDYEQIKYHHIVVNVKDHGSPSLSSRSNVFITGRILCRFISYKLIYDSIIPV 2455 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 +D+NDNAP F + VS G + +AYD D L Y K GN Sbjct: 2456 KDLNDNAPCFVEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEY----KIVYGNELQ 2511 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 +ID +G + L+ ++ L ++ +DG +A A F Sbjct: 2512 TYSIDKLTGVISLQNMLNFTDKSSTVLNISVSDG---VHTAYARLKISLLPENVYSPLFD 2568 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITV 425 YE ++ E+ G ++T+ A+D D L+YEI + F I G+IT Sbjct: 2569 QSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYYEIVSEEMKKIFLIDQTT--GVITS 2626 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 D +++ YV+ + +D GG+ A +++ + D N+ P F Y V Sbjct: 2627 KVTFDREKKDEYVVLLKVSDGGGKFGFASLKVIVVDVNDNVPYFLLKEYKMVVSTTVEAN 2686 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 T+L V A D D+ N + + + + +++AV IN +TG I + ++ Sbjct: 2687 QTILTVKAKDDDIVDNGSVHFQIVQKSNDKAV---KDVIEINEKTGDIVFKSKAESYGVN 2743 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 Y V A D G P V I +++ + N P F++ I+E GT +++ Sbjct: 2744 SYQFFVRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVLTK--- 2800 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 + + G ++ ++ + D SG + + LDRE +H+L VA P Sbjct: 2801 ----LHMIGNYTFKFSIAADQDHFMISD--SGELILQQTLDREQQESHNLIVVAETSTVP 2854 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 + V I + D ND+ P F++ + ++ENS ++ ++ A D D GPN + Y Sbjct: 2855 VFFAYADVLIDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYY 2914 Query: 726 IKGGDDS--NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEIL 783 ++ ++ N F ++ G L+T +D + +S + P V V I Sbjct: 2915 LESDTENIQNIFDIDIYSG--WITLLTSLDREVQSEYNFKVIAADNGHPKHDAKVPVTIK 2972 Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV-TDKLQYRILSGNNANLILL 842 + D NDNAPV K + +++ P + D D+ ++ + I+SG+ + Sbjct: 2973 IVDYNDNAPVFKLPIEGLSVFENALPGTVLINLLLIDPDIEKQEMDFFIVSGDKQAQFQI 3032 Query: 843 NETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889 + +G + ++ L+ + + TDG KA +++ V+ I + Sbjct: 3033 GK-SGELFIAKPLDREQLMFYNLSIIATDGKFTAKANVEIDVKDIND 3078 Score = 239 bits (585), Expect = 8e-61 Identities = 229/846 (27%), Positives = 368/846 (43%), Gaps = 88/846 (10%) Query: 86 VQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145 + + FRI+ +G ++ ++D E + + + VK T+ A+ SS I ++I+D ND Sbjct: 1753 INESFRINPSTGVIVINGNIDYESIKVFNLTVKGTNMAAE-----SSCQNIIIHILDAND 1807 Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAK--------IKATDADVGANSAIRYAIIGGNTQ 197 N P F + Y ++ E ++ + ++ DADVG N + Y I+ + Sbjct: 1808 NIPYFVQNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVKDADVGVNGMVEYHIVDDLAK 1867 Query: 198 MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR--DVNDNAP 255 F IDS +G + L++ LDYE Y + D G P +TT + IR +VND P Sbjct: 1868 NFFKIDSTTGAIELLRQLDYETNAGYTFDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPP 1927 Query: 256 RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315 F ++ + +V A DAD N L + + D GN + I+ + Sbjct: 1928 VFNERELNVTLFLPTFENVFVRQVSAKDAD---NDTLRFDIVD----GNTNECFQIEKYT 1980 Query: 316 GWVYTSGQ--LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373 G + T L+ E Y L V A+DG SA F Y Sbjct: 1981 GIITTRNFEILNNENDRDYALHVRASDG---IFSAILIVKIKVLSAIDSNFAFQRESYRF 2037 Query: 374 ELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ 433 E+ + + D + Y I N F I +G L T D + Sbjct: 2038 SAFENNTKVATIGLVNVIGNTLDENVEYRIL--NPTQLFDIGISSG-ALKTTGVIFDREV 2094 Query: 434 ERRYVLTVSAT-------DSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 + Y L V A +S R + I++ D N+ P+F N PY A+V D P GT Sbjct: 2095 KDLYRLFVEAKSMLYDGMNSNVRRAVTSIDISVLDVNDNCPLFVNMPYYATVSIDDPKGT 2154 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 ++ V A D D N ++ Y L + + F ++ ++G ++ + ++ + Sbjct: 2155 IIMQVKAIDLDSAENGEVRYELKKG--------NGELFKLDRKSGELSIKQHVEGHNRN- 2205 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y LTV A DG + S +++ V+D + PVF++Q YT ++ ED + +++S + Sbjct: 2206 YELTVAAYDGAITPCSSEAPLQVKVID--RSMPVFEKQFYTVSVKEDVEMYSALSV--SI 2261 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 +A+ L + Y + E SF ID +G I LD E +++HD+ A D + Sbjct: 2262 EAESPLGRSLIYTISS---ESQSFEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLSGV 2318 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY-- 724 + V++ + I D+ND P ESD I EN+ GT I +I A D D G NA + Y Sbjct: 2319 YAE-VVLSVSIMDVNDCYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYI 2377 Query: 725 -SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRV 780 SI G ++S F ++ G+ L LDYE K + +V+ SP L + V Sbjct: 2378 ESINGQNNSELFYIDVTDGN----LYLKTPLDYEQ-IKYHHIVVNVKDHGSPSLSSRSNV 2432 Query: 781 EIL-------------------VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVP-AYD 820 I V D+NDNAP + F G F +P AYD Sbjct: 2433 FITGRILCRFISYKLIYDSIIPVKDLNDNAPCFVE-PSYFTKVSVAAVRGQFVALPKAYD 2491 Query: 821 ADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKA 878 D+ TD L+Y+I+ GN +++ TG ++L LN + +SV+DGV+ A Sbjct: 2492 KDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQNMLNFTDKSSTVLNISVSDGVHTAYA 2551 Query: 879 MMQLSV 884 +++S+ Sbjct: 2552 RLKISL 2557 Score = 236 bits (578), Expect = 6e-60 Identities = 191/635 (30%), Positives = 298/635 (46%), Gaps = 28/635 (4%) Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293 SPS + L + N + P F + S++E+V +G ++ ++A D D G N +L Sbjct: 746 SPSVFSDLSLTPSRYGQNVHRPEFVNFPQELSINESVQLGETVAWIEAKDRDLGYNGKLV 805 Query: 294 YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353 + ++D DY D IDP G + G LDRE Q +Y L +T D G+P +S + Sbjct: 806 FAISDGDY----DSVFRIDPDRGELQIIGYLDRERQNEYVLNITVYDLGNPTKSTSKMLP 861 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS 413 L E GT V L ATDA D+ ++ ++T + Sbjct: 862 ITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHATDA--DSGINAQVTYALSVECSD 919 Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFEN 471 T G + + +PLD +++ Y L ++A D G S A+V + + D N+ APVF Sbjct: 920 FTVNATTGCLRLNKPLDREKQDNYALHITAKDGGSPVLSSEALVYVLVDDVNDNAPVFGV 979 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 Y V ED P GT + V+ A D D+G NA+I +SL E +E + F I+ TG Sbjct: 980 QEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSLKEETQDE------ELFRIDKHTG 1033 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE--PVFKQQLYTAN 589 AI T LD E + L V+A DGG PSL+ + I ++DVN+N P F +Y Sbjct: 1034 AIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMIIDVNENRFAPEFDDFVYEGK 1093 Query: 590 IMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648 + E+ GT V V A D D V LN +I Y + D G F ++ G I + LD E Sbjct: 1094 VKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGD-GLGIFAVND-QGSITSLSQLDAE 1151 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 + + L A D P S+ V V+I++E+ ND+ P+ + ++E S I Sbjct: 1152 TKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVENVEIIT 1211 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK-YELVI 767 ++A DPD P + Y+I G+ F ++++ G K T LD E+ + E+ I Sbjct: 1212 LKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTGVIK---TTERKLDRENQAEHILEVAI 1268 Query: 768 R-AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTD 825 SP L + R+ + V D+NDN+P D ++ V +V A D+D + Sbjct: 1269 SDNGSPVLSSTSRIVVSVLDINDNSPEF-DQRVYKVQVPSSATVNQSIFQVHAIDSDSGE 1327 Query: 826 --KLQYRILSGNNANLILLNETTGSMTLSPQLNTN 858 ++ Y I SG N ++ G + ++ L+++ Sbjct: 1328 NGRITYSIKSGKGKNKFRIDSQRGHIHIAKPLDSD 1362 Score = 229 bits (561), Expect = 6e-58 Identities = 235/908 (25%), Positives = 392/908 (43%), Gaps = 89/908 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+VLD ND+ P+F Y A+V GT ++ +KA D D +N EV Y ++ Sbjct: 2125 ISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVKAIDLDSAENGEVRYELKKGNG--- 2181 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 ++F++D +SG L + ++ Y + V A D A Sbjct: 2182 -----------------ELFKLDRKSGELSIKQHVEGHN-RNYELTVAAYDGA---ITPC 2220 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SS A + V +ID + P F ++ YTVSV ED+ + A + +A+ ++ Y Sbjct: 2221 SSEAPLQVKVID--RSMPVFEKQFYTVSVKEDVEMYS----ALSVSIEAESPLGRSLIYT 2274 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I + F ID +G + +V LDYE++ S+ + IRA D S + L ++I DV Sbjct: 2275 I--SSESQSFEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLSGVYAEVV-LSVSIMDV 2331 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 ND P + ++ ++ EN G I+++ A D D G NA+L+Y + + N +L Sbjct: 2332 NDCYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSEL-FY 2390 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX----- 365 ID G +Y LD E + ++V D G P S+ + Sbjct: 2391 IDVTDGNLYLKTPLDYEQIKYHHIVVNVKDHGSPSLSSRSNVFITGRILCRFISYKLIYD 2450 Query: 366 --------------FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTR 409 F+ Y +++ G V A D D + + L Y+I GN Sbjct: 2451 SIIPVKDLNDNAPCFVEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKIVYGNEL 2510 Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVF 469 +SI G+I++ L+F + VL +S +D G + A ++I++ N Y+P+F Sbjct: 2511 QTYSIDKLT--GVISLQNMLNFTDKSSTVLNISVSD-GVHTAYARLKISLLPENVYSPLF 2567 Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 + + Y A V E+ G ++ V A+D D G A + Y + SE + F+I+ Sbjct: 2568 DQSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYYEIVSEEMKKI-------FLIDQT 2620 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589 TG IT+ DRE Y++ + DGG +++ VVDVNDN P F + Y Sbjct: 2621 TGVITSKVTFDREKKDEYVVLLKVSDGG--GKFGFASLKVIVVDVNDNVPYFLLKEYKMV 2678 Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG---SFVIDPASGVIRTNKALD 646 + ++ V A D D+ NG +H+++ K ++ I+ +G I + Sbjct: 2679 VSTTVEANQTILTVKAKDDDIVDNGSVHFQIVQKSNDKAVKDVIEINEKTGDIVFKSKAE 2738 Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706 V ++ A D G P S V V I+I + + + P FE + I E++P GT + Sbjct: 2739 SYGVNSYQFFVRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVL 2798 Query: 707 GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV 766 ++ N +SI D + F + SD EL+ LD E +V Sbjct: 2799 TKLHMIG-----NYTFKFSIAA--DQDHFMI-----SDSGELILQQTLDREQQESHNLIV 2846 Query: 767 IRAAS--PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV- 823 + S P + V I V D NDN P + + ++ V +V A DAD Sbjct: 2847 VAETSTVPVFFAYADVLIDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTG 2906 Query: 824 -TDKLQYRILSG--NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAM 879 ++Y + S N N+ ++ +G +TL L+ V +V D G + A Sbjct: 2907 PNGDIRYYLESDTENIQNIFDIDIYSGWITLLTSLDREVQSEYNFKVIAADNGHPKHDAK 2966 Query: 880 MQLSVRLI 887 + ++++++ Sbjct: 2967 VPVTIKIV 2974 Score = 195 bits (475), Expect = 2e-47 Identities = 178/641 (27%), Positives = 288/641 (44%), Gaps = 48/641 (7%) Query: 133 TATIHVNIIDDNDNYPQFSEKTYTVSVDED-ISVTDNPVIAKIKATDADVGANSAIRYAI 191 TAT+ + + + +FS Y V++ E+ + T + + VG N+ ++Y I Sbjct: 42 TATLEYRLENQLQDLYRFSHSVYNVTIPENSLGKTYAKGVLHERLAGLRVGLNAEVKYRI 101 Query: 192 IGGNTQMQFSIDS-LSGDVSL--VKT------LDYEQVRSYRLVIRAQ----DGGSPSRS 238 I G+ + F + L GD + ++T L+ E+ Y + ++A D S Sbjct: 102 ISGDKEKLFKAEEKLVGDFAFLAIRTRTNNVVLNREKTEEYVIRVKAHVHLHDRNVSSYE 161 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT-MT 297 + I + D ND +P FY + + + E+ P SI++V A DAD G+N E+ Y+ + Sbjct: 162 TEANIHIKVLDRNDLSPLFYPTQYTVVIPEDTPKYQSILKVTADDADLGINGEIYYSLLM 221 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357 D +Y I P +G + QL + ++L V A D G Sbjct: 222 DSEY-------FAIHPTTGEITLLQQLQYAENSHFELTVVAYDRGSWVNHQNHQASKTKV 274 Query: 358 XXXXXXXXF-MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH-----YEITGGNTRGR 411 F P + + P P++ D+D ++ EI GN G Sbjct: 275 SISVKQVNFYAPEIFTKTFSSVTPTSNPLIYGIVRVNDKDTGINGNIGRLEIVDGNPDGT 334 Query: 412 FSITSQNGRG--LITVAQPLDFKQER-RYVLTVSATDSG--GRSDTAMVQINITDANNYA 466 F + + + I + Q Q+ Y LT+ A D G R V I I + Sbjct: 335 FLLKAAETKDEYYIELNQFAHLNQQHFIYNLTLLAEDLGTPRRFAYKSVPIQIKPESKNI 394 Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 P+F Y S+ E API V+ + +D D+G NA + + NE +F I Sbjct: 395 PIFTQEIYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVG--GNEG-----DEFRI 447 Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARD-GGVPSLSDTT-DVEISVVDVNDNEPVFKQQ 584 NP +G + T K LD E S Y LTV+A D V S ++ V+ISV D+NDN+P+F+ Sbjct: 448 NPDSGMLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIFENV 507 Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA 644 +I E+ L G+ V ++ A D D G N I Y + + F ID SG+++T Sbjct: 508 NKVISINENNLAGSFVVKLTAKDRDSGENSYISYSI--ANLNAVPFEIDHFSGIVKTTSL 565 Query: 645 LDRESV-ATHDLKAVAIDGGTPPQSSTVI-VHIKIEDINDSPPVFESDCLTFYISENSPI 702 LD E++ ++L A D G P + T I + I ++DIND+ P FE +++++P+ Sbjct: 566 LDFETMKRNYELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFERVNCYGKVTKSAPM 625 Query: 703 GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 GT + A D D G ++ Y + G++ F+L+ GS Sbjct: 626 GTEVFVTSAIDFDAGD--IISYRLSDGNEDGCFNLDPTSGS 664 Score = 176 bits (429), Expect = 6e-42 Identities = 153/552 (27%), Positives = 255/552 (46%), Gaps = 51/552 (9%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLI 423 F P QY V + ED P ++ +TA DAD + ++Y + + F+I G I Sbjct: 180 FYPTQYTVVIPEDTPKYQSILKVTADDADLGINGEIYYSLLMDSEY--FAIHPTTGE--I 235 Query: 424 TVAQPLDFKQERRYVLTVSATDSGG-------RSDTAMVQINITDANNYAPVFENAPYTA 476 T+ Q L + + + LTV A D G ++ V I++ N YAP +++ Sbjct: 236 TLLQQLQYAENSHFELTVVAYDRGSWVNHQNHQASKTKVSISVKQVNFYAPEIFTKTFSS 295 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITY------SLSSEISNEAVAHHDQQFVINPQT 530 P+ +V D D GIN I + +A D+ ++ Q Sbjct: 296 VTPTSNPL--IYGIVRVNDKDTGINGNIGRLEIVDGNPDGTFLLKAAETKDEYYIELNQF 353 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590 + + Y LT+ A D G P V I + + N P+F Q++Y +I Sbjct: 354 AHLNQQHFI-------YNLTLLAEDLGTPRRFAYKSVPIQIKPESKNIPIFTQEIYEVSI 406 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650 E A + V ++ +D D+G N ++ E+ E F I+P SG++ T K LD E Sbjct: 407 PETAPINMPVIRLKVSDPDLGKNALVYLEI-VGGNEGDEFRINPDSGMLYTAKQLDAEKK 465 Query: 651 ATHDLKAVAIDG---GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 +++ L AID G+ QSS V I ++D+ND+ P+FE+ I+EN+ G+ + Sbjct: 466 SSYTLTVSAIDQANVGSRKQSSAK-VKISVQDMNDNDPIFENVNKVISINENNLAGSFVV 524 Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 ++ A D D G N+ + YSI + N+ E S + ++ LD+E+ ++ YEL+I Sbjct: 525 KLTAKDRDSGENSYISYSIA---NLNAVPFEIDHFSGIVKTTSL--LDFETMKRNYELII 579 Query: 768 RAASPPL----WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR----VPAY 819 RA+ L ++++ I+V D+NDN P F+ + N Y P G A Sbjct: 580 RASDWGLPYRRQTEIKLSIVVKDINDNRP---QFERV-NCYGKVTKSAPMGTEVFVTSAI 635 Query: 820 DADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAM 879 D D D + YR+ GN L+ T+GS+++S L ++VS TDG + + Sbjct: 636 DFDAGDIISYRLSDGNEDGCFNLDPTSGSLSISCDLKKTTLTNRILKVSATDGTHFSDDL 695 Query: 880 MQLSVRLITEEM 891 + ++V L+ E++ Sbjct: 696 I-INVHLMPEDL 706 Score = 155 bits (376), Expect = 2e-35 Identities = 153/563 (27%), Positives = 252/563 (44%), Gaps = 59/563 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I VLD ND SP+F QY + E ++L + A D D+G N E+ Y++ + + Sbjct: 168 IKVLDRNDLSPLFYPTQYTVVIPEDTPKYQSILKVTADDADLGINGEIYYSLLMDS---- 223 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS--D 128 + F I +G + L + + + + V A D+ S V+ + Sbjct: 224 -----------------EYFAIHPTTGEITLLQQLQYAENSHFELTVVAYDRGSWVNHQN 266 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVI-AKIKATDADVGANSAI 187 +S + +++ N P+ KT++ ++ T NP+I ++ D D G N I Sbjct: 267 HQASKTKVSISVKQVNFYAPEIFTKTFS-----SVTPTSNPLIYGIVRVNDKDTGINGNI 321 Query: 188 -RYAIIGGNTQMQFSIDSL-SGDVSLVKTLDYEQVRS----YRLVIRAQDGGSPSRSNTT 241 R I+ GN F + + + D ++ + + Y L + A+D G+P R Sbjct: 322 GRLEIVDGNPDGTFLLKAAETKDEYYIELNQFAHLNQQHFIYNLTLLAEDLGTPRRFAYK 381 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 + I I+ + N P F +++ S+ E PI ++R++ D D G NA L Y + Sbjct: 382 SVPIQIKPESKNIPIFTQEIYEVSIPETAPINMPVIRLKVSDPDLGKNA-LVYL---EIV 437 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD--PPRSATATXXXXXXXX 359 GN I+P SG +YT+ QLD E ++ Y L V+A D + + ++A Sbjct: 438 GGNEGDEFRINPDSGMLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDM 497 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQ 417 F + + E+ G+ VV LTA D D E++ + Y I N F I Sbjct: 498 NDNDPIFENVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSIANLNA-VPFEI--D 554 Query: 418 NGRGLITVAQPLDFK-QERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAP 473 + G++ LDF+ +R Y L + A+D G R + I + D N+ P FE Sbjct: 555 HFSGIVKTTSLLDFETMKRNYELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFERVN 614 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 V + AP+GT V V SA D D G I+Y LS NE D F ++P +G++ Sbjct: 615 CYGKVTKSAPMGTEVFVTSAIDFDAG--DIISYRLSD--GNE-----DGCFNLDPTSGSL 665 Query: 534 TTNKLLDRETMSGYLLTVTARDG 556 + + L + T++ +L V+A DG Sbjct: 666 SISCDLKKTTLTNRILKVSATDG 688 Score = 120 bits (290), Expect = 4e-25 Identities = 105/360 (29%), Positives = 164/360 (45%), Gaps = 33/360 (9%) Query: 453 AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512 A + I + D N+ +P+F YT + ED P ++L V+A D+D+GIN +I YSL + Sbjct: 164 ANIHIKVLDRNDLSPLFYPTQYTVVIPEDTPKYQSILKVTADDADLGINGEIYYSLLMD- 222 Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG-----VPSLSDTTDV 567 + F I+P TG IT + L S + LTV A D G + T V Sbjct: 223 --------SEYFAIHPTTGEITLLQQLQYAENSHFELTVVAYDRGSWVNHQNHQASKTKV 274 Query: 568 EISVVDVNDNEP-VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE 626 ISV VN P +F + + + L+ V D D G+NG I Sbjct: 275 SISVKQVNFYAPEIFTKTFSSVTPTSNPLI---YGIVRVNDKDTGINGNIGRLEIVDGNP 331 Query: 627 EGSFVIDPASG----VIRTNK-ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681 +G+F++ A I N+ A + ++L +A D GTP + + V I+I+ + Sbjct: 332 DGTFLLKAAETKDEYYIELNQFAHLNQQHFIYNLTLLAEDLGTPRRFAYKSVPIQIKPES 391 Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741 + P+F + I E +PI + ++ DPD G NA+V+ I GG++ + F R Sbjct: 392 KNIPIFTQEIYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVGGNEGDEF----RI 447 Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRA-----ASPPLWNDVRVEILVTDVNDNAPVMKD 796 D L T LD E + Y L + A + +V+I V D+NDN P+ ++ Sbjct: 448 NPDSGMLYTAKQLDAEK-KSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIFEN 506 Score = 97.5 bits (232), Expect = 5e-18 Identities = 116/456 (25%), Positives = 190/456 (41%), Gaps = 27/456 (5%) Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI---TTNKLLDRETMSGYLLTVTAR 554 VG+NA++ Y + S E + +++ V + AI T N +L+RE Y++ V A Sbjct: 91 VGLNAEVKYRIISG-DKEKLFKAEEKLVGDFAFLAIRTRTNNVVLNREKTEEYVIRVKAH 149 Query: 555 ----DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610 D V S ++ I V+D ND P+F YT I ED S+ +V A DAD+ Sbjct: 150 VHLHDRNVSSYETEANIHIKVLDRNDLSPLFYPTQYTVVIPEDTPKYQSILKVTADDADL 209 Query: 611 GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT-----P 665 G+NG I+Y L D E F I P +G I + L + +L VA D G+ Sbjct: 210 GINGEIYYSL-LMDSE--YFAIHPTTGEITLLQQLQYAENSHFELTVVAYDRGSWVNHQN 266 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA-VVHY 724 Q+S V I ++ +N P + + ++P+ G +R +D D G N + Sbjct: 267 HQASKTKVSISVKQVNFYAPEIFTKTFSSVTPTSNPL--IYGIVRVNDKDTGINGNIGRL 324 Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVE 781 I G+ +F L+ + D+ + Y L + A +P + V Sbjct: 325 EIVDGNPDGTFLLKAAETKDEYYIELNQFAHLNQQHFIYNLTLLAEDLGTPRRFAYKSVP 384 Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADV-TDKLQY-RILSGNNAN 838 I + + N P+ +I + + P+ P R+ D D+ + L Y I+ GN + Sbjct: 385 IQIKPESKNIPIFTQ-EIYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVGGNEGD 443 Query: 839 LILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN-EIKAMMQLSVRLITEEMLLNSIT 897 +N +G + + QL+ T+ VS D N + V++ ++M N Sbjct: 444 EFRINPDSGMLYTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPI 503 Query: 898 VRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYI 933 + + L G F+ L A EN YI Sbjct: 504 FENVNKVISINENNLAGSFVVKLTAKDRDSGENSYI 539 Score = 70.1 bits (164), Expect = 8e-10 Identities = 63/225 (28%), Positives = 101/225 (44%), Gaps = 29/225 (12%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I+V D ND+ P+FE S+ E +G+ V+ L A D+D G+N+ + Y+I + A Sbjct: 491 KISVQDMNDNDPIFENVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSIANLNAVP 550 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSD 128 F ID SG + T + LD E + R Y ++++A+D P Sbjct: 551 --------------------FEIDHFSGIVKTTSLLDFETMKRNYELIIRASDWGLPY-- 588 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA-DVGANSAI 187 R + + + + D NDN PQF V + P+ ++ T A D A I Sbjct: 589 RRQTEIKLSIVVKDINDNRPQFERVNCYGKVTKSA-----PMGTEVFVTSAIDFDAGDII 643 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232 Y + GN F++D SG +S+ L + + L + A DG Sbjct: 644 SYRLSDGNEDGCFNLDPTSGSLSISCDLKKTTLTNRILKVSATDG 688 Score = 44.0 bits (99), Expect = 0.061 Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 4/52 (7%) Query: 1535 STCTCEAGRVGPQC---VSACELGPCGAAR-CVPDQTPKGYSCACEPGYTLT 1582 +TC C G G C V+AC PC R C+P + GY C C G++ T Sbjct: 3865 NTCVCRPGFDGKHCKETVNACSTDPCSPQRICMPSGSALGYQCVCPKGFSGT 3916 >UniRef50_A6NIM4 Cluster: Uncharacterized protein FAT3; n=43; Euteleostomi|Rep: Uncharacterized protein FAT3 - Homo sapiens (Human) Length = 4558 Score = 433 bits (1066), Expect = e-119 Identities = 389/1370 (28%), Positives = 612/1370 (44%), Gaps = 126/1370 (9%) Query: 1 MSVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEY 60 + + F + I VLD ND+ PVFE Y+ + EG GT + ++A D D G N +V Y Sbjct: 2793 VDIVFTVDVDIKVLDLNDNKPVFETSSYDTIIMEGMPVGTKLTQVRAIDMDWGANGQVTY 2852 Query: 61 TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT 120 ++ +D+ PE V + F ID +G + T LD E +T V A+ Sbjct: 2853 SLH---SDS-QPEK-----------VMEAFNIDSNTGWISTLKDLDHETDPTFTFSVVAS 2897 Query: 121 DQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD 180 D S LSSTA + V + D NDN P F+++ Y +V E S V+A + D D Sbjct: 2898 DLGEAFS--LSSTALVSVRVTDINDNAPVFAQEVYRGNVKE--SDPPGEVVAVLSTWDRD 2953 Query: 181 VG-ANSAIRYAIIGGNTQMQFSIDSLSGD--VSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237 N + Y I GGN + +F++ + + V + + LD E+ Y L I A DG ++ Sbjct: 2954 TSDVNRQVSYHITGGNPRGRFALGLVQSEWKVYVKRPLDREEQDIYFLNITATDGLFVTQ 3013 Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297 + + +++ DVNDN+P + + E++P I++V A DAD G N + Y++ Sbjct: 3014 A---MVEVSVSDVNDNSPVCDQVAYTALLPEDIPSNKIILKVSAKDADIGSNGYIRYSLY 3070 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357 +GN + +DP SG + T LDRE Y L+ ATDGG R + Sbjct: 3071 G---SGNSEF--FLDPESGELKTLALLDRERIPVYSLMAKATDGGG--RFCQSNIHLILE 3123 Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITS 416 F Y + E+ + + A D D NR + G FSI S Sbjct: 3124 DVNDNPPVFSSDHYNTCVYENTATKALLTRVQAVDPDIGINRKVVYSLADSAGGVFSIDS 3183 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATD-SGGRSDTAMVQINIT--DANNYAPVFENAP 473 +G +I + QPLD +Q+ Y ++V ATD S G+S +++ + IT D N+ PVFE Sbjct: 3184 SSG--IIILEQPLDREQQSSYNISVRATDQSPGQSLSSLTTVTITVLDINDNPPVFERRD 3241 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 Y +V ED GT VL V AT D+G NA+ITY + S NE +F INP+TG I Sbjct: 3242 YLVTVPEDTSPGTQVLAVFATSKDIGTNAEITYLIRS--GNE-----QGKFKINPKTGGI 3294 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593 + +++LD E + L V A+DGG P+LS V I++ DVNDN P F Q +Y+A I ED Sbjct: 3295 SVSEVLDYELCKRFYLVVEAKDGGTPALSAVATVNINLTDVNDNPPKFSQDVYSAVISED 3354 Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653 ALVG SV + A D D NG+IH+ + DR + F +DP G+++ K LDRE V+ + Sbjct: 3355 ALVGDSVILLIAEDVDSQPNGQIHFSIVNGDR-DNEFTVDPVLGLVKVKKKLDRERVSGY 3413 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713 L A+D G P SST V+I I D+ND+ PVF T I EN P+GT+I ++ D Sbjct: 3414 SLLVQAVDSGIPAMSSTATVNIDISDVNDNSPVFTPANYTAVIQENKPVGTSILQLVVTD 3473 Query: 714 PDEGPNA-VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA--- 769 D N +SI G++ F L+ G ++ +V + +Y L ++A Sbjct: 3474 RDSFHNGPPFSFSILSGNEEEEFVLDP-HGILRSAVVFQ-----HTESLEYVLCVQAKDS 3527 Query: 770 ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQY 829 P + + + V + + + P +I +D FP G G++ A D D+ D L + Sbjct: 3528 GKPQQVSHTYIRVRVIEESTHKPTAIPLEIFIVTMEDDFPGGVIGKIHATDQDMYDVLTF 3587 Query: 830 RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889 L +L +N G + L++ + VSV+DG ++ + + V + Sbjct: 3588 -ALKSEQKSLFKVNSHDGKIIALGGLDSG---KYVLNVSVSDGRFQVPIDVVVHVEQLVH 3643 Query: 890 EMLLNSITVRLNDMTAEQFLS-PLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTG-NIL 947 EML N++T+R +++ E F+ + GF A++ ++++ I S+Q V G N L Sbjct: 3644 EMLQNTVTIRFENVSPEDFVGLHMHGFRRTLRNAVLTQKQDSLRIISIQ---PVAGTNQL 3700 Query: 948 NVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPC 1007 ++ F+ +E Y P +L +++ R L + + + + N C C Sbjct: 3701 DMLFAVEMHSSE---------FYKPAYLIQKLSNARRHLENIMRISAI-LEKN-CSGLDC 3749 Query: 1008 LNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVD 1067 + C L ++S +++ Y + CP + V C C Sbjct: 3750 QE-QHCEQGLS-------LDSHALM---TYSTARISFVCPRFYRNVRC--TCNGGLCPGS 3796 Query: 1068 GDGSI---CRSGSQCVARREG--GILCQGCSIDAAYTTAVCELRARSFPVSSFLTF--PG 1120 D + C QCV+ LCQ + L SF +S++ + Sbjct: 3797 NDPCVEKPCPGDMQCVSYEASRRPFLCQCPPGKLGECSGHTSL---SFAGNSYIKYRLSE 3853 Query: 1121 LKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRGGGPGLRFSFSLGG 1180 + L L+ T ++G+++ Y + + L++V + L F G Sbjct: 3854 NSKEEDFKLALRLRTLQSNGIIM----YTRANPCIILKIVDGK--------LWFQLDCGS 3901 Query: 1181 GKSEITVEGN-VGDGSWHTVEIEYFNRTITMILDDCDKVLSLAGAADFGLKYACANFTRK 1239 G + + G V DGSWH+V +E NR T + D D + A Y T Sbjct: 3902 GPGILGISGRAVNDGSWHSVFLE-LNRNFTSLSLD-DSYVERRRAP----LYFQTLSTES 3955 Query: 1240 VLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNS 1299 + + + D + G S + N ++ + +K Sbjct: 3956 SIYFGALVQADNIRSLTDTRVTQVLSGFQGCLDSVILNN-------NELPLQNKRSSFAE 4008 Query: 1300 YVADNGTLAGCPEKRSRCSSAPCYNGAECSDL-WDTYICDCKEGHTGKDC 1348 V GC C +PC +G C+ L Y C C TG++C Sbjct: 4009 VVGLTELKLGCVLYPDACKRSPCQHGGSCTGLPSGGYQCTCLSQFTGRNC 4058 Score = 339 bits (834), Expect = 5e-91 Identities = 241/798 (30%), Positives = 382/798 (47%), Gaps = 51/798 (6%) Query: 5 FCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIEL 64 FC + I V+D ND++P F +Y ASVR G V ++A D D G N+ + Y++ Sbjct: 2584 FCTVRVI-VVDENDNAPQFMTVEYRASVRADVGRGHLVTQVQAIDPDDGANSRITYSL-- 2640 Query: 65 VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS 124 V D+ ID +G ++T+ + ++ K + VKA D Sbjct: 2641 --------------YSEASVSVADLLEIDPDNGWMVTKGNFNQLKNTVLSFFVKAVDGGI 2686 Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184 PV S ++++++ P F++ Y+ ++ ED ++ + ++ + Sbjct: 2687 PVK---HSLIPVYIHVLPPETFLPSFTQSQYSFTIAEDTAI--GSTVDTLRILPSQNVWF 2741 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ-DGGSPSRSNTTQL 243 S + N F I+ +G + L K LD E ++ + A T + Sbjct: 2742 STVNGERPENNKGGIFVIEQETGTIKLDKRLDRETSPAFHFKVAATIPLDKVDIVFTVDV 2801 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 I + D+NDN P F TS + + E +P+G + +V+A D D G N ++TY++ Sbjct: 2802 DIKVLDLNDNKPVFETSSYDTIIMEGMPVGTKLTQVRAIDMDWGANGQVTYSLHSDSQPE 2861 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSATATXXXXXXXXXXX 362 V ID +GW+ T LD ET + V A+D G+ S+TA Sbjct: 2862 KVMEAFNIDSNTGWISTLKDLDHETDPTFTFSVVASDLGEAFSLSSTALVSVRVTDINDN 2921 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATD---ADEDNRLHYEITGGNTRGRFSITSQNG 419 F Y + E +PPG V L+ D +D + ++ Y ITGGN RGRF++ Sbjct: 2922 APVFAQEVYRGNVKESDPPGEVVAVLSTWDRDTSDVNRQVSYHITGGNPRGRFALGLVQS 2981 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479 + V +PLD +++ Y L ++ATD G AMV+++++D N+ +PV + YTA + Sbjct: 2982 EWKVYVKRPLDREEQDIYFLNITATD-GLFVTQAMVEVSVSDVNDNSPVCDQVAYTALLP 3040 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 ED P +L VSA D+D+G N I YSL ++E F ++P++G + T LL Sbjct: 3041 EDIPSNKIILKVSAKDADIGSNGYIRYSLYGSGNSE--------FFLDPESGELKTLALL 3092 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 DRE + Y L A DGG +++ + + DVNDN PVF Y + E+ Sbjct: 3093 DRERIPVYSLMAKATDGG--GRFCQSNIHLILEDVNDNPPVFSSDHYNTCVYENTATKAL 3150 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 +++V A D D+G+N ++ Y L D G F ID +SG+I + LDRE +++++ A Sbjct: 3151 LTRVQAVDPDIGINRKVVYSL--ADSAGGVFSIDSSSGIIILEQPLDREQQSSYNISVRA 3208 Query: 660 IDGGTPPQ--SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 D +P Q SS V I + DIND+PPVFE + E++ GT + + A D G Sbjct: 3209 TD-QSPGQSLSSLTTVTITVLDINDNPPVFERRDYLVTVPEDTSPGTQVLAVFATSKDIG 3267 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPL 774 NA + Y I+ G++ F + + G V LDYE K++ LV+ A +P L Sbjct: 3268 TNAEITYLIRSGNEQGKFKINPKTGGISVSEV----LDYEL-CKRFYLVVEAKDGGTPAL 3322 Query: 775 WNDVRVEILVTDVNDNAP 792 V I +TDVNDN P Sbjct: 3323 SAVATVNINLTDVNDNPP 3340 Score = 313 bits (768), Expect = 5e-83 Identities = 236/751 (31%), Positives = 361/751 (48%), Gaps = 52/751 (6%) Query: 157 VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLD 216 V+V ED+ V N I KIKA DAD G N + + I GNT F+ID +G + ++ +D Sbjct: 734 VAVKEDLPVGAN--ILKIKAYDADSGFNGKVLFTISDGNTDSCFNIDMETGQLKVLMPMD 791 Query: 217 YEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSI 276 E Y L I D G+P +S+ L IN+ D NDN+P F + ++ E+ IG I Sbjct: 792 REHTDLYLLNITIYDLGNPQKSSWRLLTINVEDANDNSPVFIQDSYSVNILESSGIGTEI 851 Query: 277 VRVQAYDADEGVNAELTYT-MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL 335 ++V+A D D G N E+TY+ +TD I+ +G VY + QLDRE++A Y L Sbjct: 852 IQVEARDKDLGSNGEVTYSVLTDTQ-------QFAINSSTGIVYVADQLDRESKANYSLK 904 Query: 336 VTATDGGDPPRS--ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393 + A D + + + T F+P Y V++ ED P GT + L D Sbjct: 905 IEARDKAESGQQLFSVVTLKVFLDDVNDCSPAFIPSSYSVKVLEDLPVGTVIAWLETHDP 964 Query: 394 D--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG---G 448 D ++ Y + + GRF I G I +++ LD+++++ Y LTV A D G Sbjct: 965 DLGLGGQVRYSLV-NDYNGRFEI--DKASGAIRLSKELDYEKQQFYNLTVRAKDKGRPVS 1021 Query: 449 RSDTAMVQINITDANN--YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506 S + V++ + D N + P F + SV E++ IGT+VL V+A D D G + +I Y Sbjct: 1022 LSSVSFVEVEVVDVNENLHTPYFPDFAVVGSVKENSRIGTSVLQVTARDEDSGRDGEIQY 1081 Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566 S+ + +F I+ ++G IT +LDRETM Y LTV A D GV L T + Sbjct: 1082 SIR---DGSGLG----RFSIDDESGVITAADILDRETMGSYWLTVYATDRGVVPLYSTIE 1134 Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE 626 V I V DVNDN P+ + +Y +ME++ SV Q+ A D D N ++ Y + Sbjct: 1135 VYIEVEDVNDNAPLTSEPIYYPVVMENSPKDVSVIQIQAEDPDSSSNEKLTYRI-TSGNP 1193 Query: 627 EGSFVIDPASGVI-RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685 + F I+ +G+I T++ LDRE A H L+ DGG P+ ST+ V +++ D ND+ P Sbjct: 1194 QNFFAINIKTGLITTTSRKLDREQQAEHFLEVTVTDGGPSPKQSTIWVVVQVLDENDNKP 1253 Query: 686 VFESDCLTFYISE--NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 F + E G I A D DEGPNA + YSI G+D F ++ + G Sbjct: 1254 QFPEKVYQIKLPERDRKKRGEPIYRAFAFDRDEGPNAEISYSIVDGNDDGKFFIDPKTG- 1312 Query: 744 DKAELVTMVDLDYESPRKKYE-LVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQI 799 MV + Y+ L I+A P + R+ I +P+ F Sbjct: 1313 -------MVSSRKQFTAGSYDILTIKAVDNGRPQKSSTARLHIEWIKKPPPSPIPLTFDE 1365 Query: 800 IFNNY---KDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 F N+ + G V A+ L + I+ GN + + G++ ++ L+ Sbjct: 1366 PFYNFTVMESDRVTEIVGVVSVQPANT--PLWFDIVGGNFDSAFDAEKGVGTIVIAKPLD 1423 Query: 857 TNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887 + M V VTDG N A+ Q+ ++++ Sbjct: 1424 AEQRSIYNMSVEVTDGTN--VAVTQVFIKVL 1452 Score = 310 bits (760), Expect = 5e-82 Identities = 254/860 (29%), Positives = 400/860 (46%), Gaps = 74/860 (8%) Query: 10 QINVLDCND--HSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 ++ V+D N+ H+P F SV+E + GT+VL + A D+D G++ E++Y+I Sbjct: 1029 EVEVVDVNENLHTPYFPDFAVVGSVKENSRIGTSVLQVTARDEDSGRDGEIQYSI----- 1083 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 D F ID SG + LDRE + Y + V ATD+ Sbjct: 1084 -----RDGSGLGR---------FSIDDESGVITAADILDRETMGSYWLTVYATDRGVV-- 1127 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 L ST +++ + D NDN P SE Y V E+ S D VI +I+A D D +N + Sbjct: 1128 -PLYSTIEVYIEVEDVNDNAPLTSEPIYYPVVMEN-SPKDVSVI-QIQAEDPDSSSNEKL 1184 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLV-KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 Y I GN Q F+I+ +G ++ + LD EQ + L + DGG + +T +++ Sbjct: 1185 TYRITSGNPQNFFAINIKTGLITTTSRKLDREQQAEHFLEVTVTDGGPSPKQSTIWVVVQ 1244 Query: 247 IRDVNDNAPRFYTSLFQESVSE--NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + D NDN P+F ++Q + E G I R A+D DEG NAE++Y++ D GN Sbjct: 1245 VLDENDNKPQFPEKVYQIKLPERDRKKRGEPIYRAFAFDRDEGPNAEISYSIVD----GN 1300 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLL-VTATDGGDPPRSATATXXXXXXXX---X 360 D IDP++G V + Q T Y +L + A D G P +S+TA Sbjct: 1301 DDGKFFIDPKTGMVSSRKQF---TAGSYDILTIKAVDNGRPQKSSTARLHIEWIKKPPPS 1357 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420 F Y + E + T +V + + + L ++I GGN F ++ G Sbjct: 1358 PIPLTFDEPFYNFTVMESDRV-TEIVGVVSVQ-PANTPLWFDIVGGNFDSAFD--AEKGV 1413 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 G I +A+PLD +Q Y ++V TD G V I + D N+ P F Y ++ E Sbjct: 1414 GTIVIAKPLDAEQRSIYNMSVEVTD-GTNVAVTQVFIKVLDNNDNGPEFSQPNYDVTISE 1472 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 D T +L + ATD D +++Y++ S I + ++ ++F I+P TG + T + LD Sbjct: 1473 DVLPDTEILQIEATDRDE--KHKLSYTVHSSIDSISM----RKFRIDPSTGVLYTAERLD 1526 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 E ++L + RD P + V ++V D ND+ P F LY A++ E A +G++V Sbjct: 1527 HEAQDKHILNIMVRDQEFPYRRNLARVIVNVEDANDHSPYFTNPLYEASVFESAALGSAV 1586 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 QV A D D G N + Y ++ F I+P G+I K D ++ L Sbjct: 1587 LQVTALDKDKGENAELIYTIE-AGNTGNMFKIEPVLGIITICKEPDMTTMGQFVLSIKVT 1645 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 D G+PP S+T IV I + ++S P F ++EN IGT++ I A + Sbjct: 1646 DQGSPPMSATAIVRISVTMSDNSHPKFIHKDYQAEVNENVDIGTSVILISAIS-----QS 1700 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS-PPLWNDVR 779 + Y +K GD + F++ G + T LDYE Y+L+I+A + + ++ Sbjct: 1701 TLIYEVKDGDINGIFTINPYSG----VITTQKALDYER-TSSYQLIIQATNMAGMASNAT 1755 Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR--------VPAYDADVTDK--LQY 829 V I + D NDNAPV F + + P+ R + A DAD L Y Sbjct: 1756 VNIQIVDENDNAPVFL-FSQYSGSLSEAAPINSIVRSLDNSPLVIRATDADSNRNALLVY 1814 Query: 830 RILSGNNANLILLNETTGSM 849 +I+ ++ +TG++ Sbjct: 1815 QIVESTAKKFFTVDSSTGAI 1834 Score = 304 bits (746), Expect = 2e-80 Identities = 251/844 (29%), Positives = 385/844 (45%), Gaps = 34/844 (4%) Query: 55 NAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYT 114 N ++ +++ + +PE F ID +G L + LD E + Y Sbjct: 2197 NEDIRMNTPILSINATSPEGQGIIYIIIDGDPFKQFNIDFDTGVLKVVSPLDYEVTSAYK 2256 Query: 115 VLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKI 174 + ++A+D + R T + VN D NDN P F + TY ++ E S+ PV+ ++ Sbjct: 2257 LTIRASDALTGA--RAEVTVDLLVN--DVNDNPPIFDQPTYNTTLSE-ASLIGTPVL-QV 2310 Query: 175 KATDADVGANSAIRYAIIGG--NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232 + DAD N + Y I+ N+ F IDS SG + + LD+E V+ L +R+ D Sbjct: 2311 VSIDADSENNKMVHYQIVQDTYNSTDYFHIDSSSGLILTARMLDHELVQHCTLKVRSIDS 2370 Query: 233 GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292 G PS S+ + I I DVNDN P F +++ VSE P G+ + VQA DAD L Sbjct: 2371 GFPSLSSEVLVHIYISDVNDNPPVFNQLIYESYVSELAPRGHFVTCVQASDADSSDFDRL 2430 Query: 293 TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352 Y++ +GN +D +SG + S + + Y L V+ +DG ++TA Sbjct: 2431 EYSIL----SGNDRTSFLMDSKSGVITLSNHRKQRMEPLYSLNVSVSDG---LFTSTAQV 2483 Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRG 410 F Y E+ E+ GT V+ + ATD D ++ Y I + Sbjct: 2484 HIRVLGANLYSPAFSQSTYVAEVRENVAAGTKVIHVRATDGDPGTYGQISYAIINDFAKD 2543 Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFE 470 RF I S NG+ + T + E + V A D GGR+ V++ + D N+ AP F Sbjct: 2544 RFLIDS-NGQVITTERLDRENPLEGDVSIFVRALDGGGRTTFCTVRVIVVDENDNAPQFM 2602 Query: 471 NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 Y ASV D G V V A D D G N++ITYSL SE S +VA I+P Sbjct: 2603 TVEYRASVRADVGRGHLVTQVQAIDPDDGANSRITYSLYSEAS-VSVA---DLLEIDPDN 2658 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590 G + T ++ + V A DGG+P V I V+ P F Q Y+ I Sbjct: 2659 GWMVTKGNFNQLKNTVLSFFVKAVDGGIPVKHSLIPVYIHVLPPETFLPSFTQSQYSFTI 2718 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE-S 649 ED +G++V + + ++ E P++ + G FVI+ +G I+ +K LDRE S Sbjct: 2719 AEDTAIGSTVDTLRILPSQNVWFSTVNGE-RPENNKGGIFVIEQETGTIKLDKRLDRETS 2777 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 A H A I TV V IK+ D+ND+ PVFE+ I E P+GT + ++ Sbjct: 2778 PAFHFKVAATIPLDKVDIVFTVDVDIKVLDLNDNKPVFETSSYDTIIMEGMPVGTKLTQV 2837 Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES-PRKKYELVIR 768 RA D D G N V YS+ S+ + T+ DLD+E+ P + +V Sbjct: 2838 RAIDMDWGANGQVTYSLHSDSQPEKVMEAFNIDSNTGWISTLKDLDHETDPTFTFSVVAS 2897 Query: 769 --AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRV-PAYDADVTD 825 + L + V + VTD+NDNAPV ++ N K+ P G V +D D +D Sbjct: 2898 DLGEAFSLSSTALVSVRVTDINDNAPVFAQ-EVYRGNVKESDPPGEVVAVLSTWDRDTSD 2956 Query: 826 ---KLQYRILSGNNANLILLN--ETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMM 880 ++ Y I GN L ++ + + L+ + + ++ TDG+ +AM+ Sbjct: 2957 VNRQVSYHITGGNPRGRFALGLVQSEWKVYVKRPLDREEQDIYFLNITATDGLFVTQAMV 3016 Query: 881 QLSV 884 ++SV Sbjct: 3017 EVSV 3020 Score = 291 bits (714), Expect = 2e-76 Identities = 253/861 (29%), Positives = 390/861 (45%), Gaps = 77/861 (8%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 D ND SP F Y V E GT + L+ D D+G +V Y++ +N + Sbjct: 929 DVNDCSPAFIPSSYSVKVLEDLPVGTVIAWLETHDPDLGLGGQVRYSL-------VNDYN 981 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134 F ID SGA+ LD EK Y + V+A D+ PVS LSS + Sbjct: 982 GR-------------FEIDKASGAIRLSKELDYEKQQFYNLTVRAKDKGRPVS--LSSVS 1026 Query: 135 TIHVNIIDDNDNY--PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192 + V ++D N+N P F + SV E+ + + + ++ A D D G + I+Y+I Sbjct: 1027 FVEVEVVDVNENLHTPYFPDFAVVGSVKENSRIGTS--VLQVTARDEDSGRDGEIQYSIR 1084 Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252 G+ +FSID SG ++ LD E + SY L + A D G +T ++ I + DVND Sbjct: 1085 DGSGLGRFSIDDESGVITAADILDRETMGSYWLTVYATDRGVVPLYSTIEVYIEVEDVND 1144 Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312 NAP ++ V EN P S++++QA D D N +LTY +T +GN I+ Sbjct: 1145 NAPLTSEPIYYPVVMENSPKDVSVIQIQAEDPDSSSNEKLTYRIT----SGNPQNFFAIN 1200 Query: 313 PRSGWV-YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371 ++G + TS +LDRE QA++ L VT TDGG P+ +T F Y Sbjct: 1201 IKTGLITTTSRKLDREQQAEHFLEVTVTDGGPSPKQSTIWVVVQVLDENDNKPQFPEKVY 1260 Query: 372 EVELAEDE--PPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 +++L E + G P+ A D DE + + Y I GN G+F I + G V+ Sbjct: 1261 QIKLPERDRKKRGEPIYRAFAFDRDEGPNAEISYSIVDGNDDGKFFIDPKTG----MVSS 1316 Query: 428 PLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPV---FENAPYTASVFEDA 482 F +LT+ A D+G +S TA + I +P+ F+ Y +V E Sbjct: 1317 RKQFTAGSYDILTIKAVDNGRPQKSSTARLHIEWIKKPPPSPIPLTFDEPFYNFTVMESD 1376 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 + V VVS + N + + + + D F G I K LD E Sbjct: 1377 RVTEIVGVVSVQPA----NTPLWFDIVG-------GNFDSAFDAEKGVGTIVIAKPLDAE 1425 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 S Y ++V DG ++ T V I V+D NDN P F Q Y I ED L T + Q Sbjct: 1426 QRSIYNMSVEVTDGTNVAV---TQVFIKVLDNNDNGPEFSQPNYDVTISEDVLPDTEILQ 1482 Query: 603 VGATDADV--GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 + ATD D L+ +H +D + F IDP++GV+ T + LD E+ H L + Sbjct: 1483 IEATDRDEKHKLSYTVHSSIDSISMRK--FRIDPSTGVLYTAERLDHEAQDKHILNIMVR 1540 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 D P + + V + +ED ND P F + + E++ +G+ + ++ A D D+G NA Sbjct: 1541 DQEFPYRRNLARVIVNVEDANDHSPYFTNPLYEASVFESAALGSAVLQVTALDKDKGENA 1600 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWND 777 + Y+I+ G+ N F +E G ++T+ + ++ L I+ SPP+ Sbjct: 1601 ELIYTIEAGNTGNMFKIEPVLG-----IITICKEPDMTTMGQFVLSIKVTDQGSPPMSAT 1655 Query: 778 VRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGN 835 V I VT +++ P + KD+Q N D +G V A L Y + G+ Sbjct: 1656 AIVRISVTMSDNSHPKFIHKDYQAEVNENVD---IGT--SVILISAISQSTLIYEVKDGD 1710 Query: 836 NANLILLNETTGSMTLSPQLN 856 + +N +G +T L+ Sbjct: 1711 INGIFTINPYSGVITTQKALD 1731 Score = 289 bits (708), Expect = 1e-75 Identities = 240/854 (28%), Positives = 398/854 (46%), Gaps = 62/854 (7%) Query: 57 EVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVL 116 E + E+V ++ P + F + G ++ LD E+ + Y + Sbjct: 1374 ESDRVTEIVGVVSVQPANTPLWFDIVGGNFDSAFDAEKGVGTIVIAKPLDAEQRSIYNMS 1433 Query: 117 VKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKA 176 V+ TD + + + + ++D+NDN P+FS+ Y V++ ED+ + D ++ +I+A Sbjct: 1434 VEVTDGTNV------AVTQVFIKVLDNNDNGPEFSQPNYDVTISEDV-LPDTEIL-QIEA 1485 Query: 177 TDADVGAN-SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP 235 TD D S ++ I + +F ID +G + + LD+E + L I +D P Sbjct: 1486 TDRDEKHKLSYTVHSSIDSISMRKFRIDPSTGVLYTAERLDHEAQDKHILNIMVRDQEFP 1545 Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295 R N ++++N+ D ND++P F L++ SV E+ +G ++++V A D D+G NAEL YT Sbjct: 1546 YRRNLARVIVNVEDANDHSPYFTNPLYEASVFESAALGSAVLQVTALDKDKGENAELIYT 1605 Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355 + + TGN+ I+P G + + D T ++ L + TD G PP SATA Sbjct: 1606 I-EAGNTGNM---FKIEPVLGIITICKEPDMTTMGQFVLSIKVTDQGSPPMSATAIVRIS 1661 Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSIT 415 F+ Y+ E+ E+ GT V+ ++A + L YE+ G+ G F+I Sbjct: 1662 VTMSDNSHPKFIHKDYQAEVNENVDIGTSVILISAI---SQSTLIYEVKDGDINGIFTIN 1718 Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYT 475 + G+IT + LD+++ Y L + AT+ G + A V I I D N+ APVF + Y+ Sbjct: 1719 PYS--GVITTQKALDYERTSSYQLIIQATNMAGMASNATVNIQIVDENDNAPVFLFSQYS 1776 Query: 476 ASVFEDAPIGTTV-------LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528 S+ E API + V LV+ ATD+D NA + Y + + + F ++ Sbjct: 1777 GSLSEAAPINSIVRSLDNSPLVIRATDADSNRNALLVYQIVESTAKKF-------FTVDS 1829 Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE--ISVVDVNDNEPVFKQQLY 586 TGAI T LD ET++ + V RD G P L+ + VE I V DVNDN PVF Q ++ Sbjct: 1830 STGAIRTIANLDHETIAHFHFHVHVRDSGSPQLTAESPVEVNIEVTDVNDNPPVFTQAVF 1889 Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR-TNKAL 645 ++ VG V +V ATD D + + Y L + F+ID SGV+ N L Sbjct: 1890 ETILLLPTYVGVEVLKVSATDPDSEVPPELTYSL--MEGSLDHFLIDSNSGVLTIKNNNL 1947 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 ++ H + V + G ST +V I +++ DS F + ISEN+ T Sbjct: 1948 SKD----HYMLIVKVSDG--KFYSTSMVTIMVKEAMDSGLHFTQSFYSTSISENNTNITK 2001 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765 + + A N + YSI + N F +++ G + T V D E ++ YEL Sbjct: 2002 VAIVNA--VGNRLNEPLKYSIL--NPGNKFKIKSTSGVIQ---TTGVPFDREE-QELYEL 2053 Query: 766 VIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD 822 V+ A+ V V + + D+NDN+PV D P +V A D D Sbjct: 2054 VVEASRELDHLRVARVVVRVNIEDINDNSPVFVGLPYYAAVQVDAEPGTLIYQVTAIDKD 2113 Query: 823 VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVT-----DGVNEIK 877 + + ++ +N +G++ L N++ L+ +E VT G + Sbjct: 2114 KGPNGEVTYVLQDDYGHFEINPNSGNVILKEAFNSD---LSNIEYGVTILAKDGGKPSLS 2170 Query: 878 AMMQLSVRLITEEM 891 ++L + ++ + M Sbjct: 2171 TSVELPITIVNKAM 2184 Score = 288 bits (706), Expect = 2e-75 Identities = 254/878 (28%), Positives = 394/878 (44%), Gaps = 68/878 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 INV D ND+SPVF Y ++ E + GT ++ ++A D+D+G N EV Y+ V DT Sbjct: 820 INVEDANDNSPVFIQDSYSVNILESSGIGTEIIQVEARDKDLGSNGEVTYS---VLTDT- 875 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F I+ +G + LDRE A Y++ ++A D+A +L Sbjct: 876 -----------------QQFAINSSTGIVYVADQLDRESKANYSLKIEARDKAES-GQQL 917 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S T+ V + D ND P F +Y+V V ED+ V VIA ++ D D+G +RY+ Sbjct: 918 FSVVTLKVFLDDVNDCSPAFIPSSYSVKVLEDLPV--GTVIAWLETHDPDLGLGGQVRYS 975 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP-SRSNTTQLLINIRD 249 ++ + +F ID SG + L K LDYE+ + Y L +RA+D G P S S+ + + + + D Sbjct: 976 LV-NDYNGRFEIDKASGAIRLSKELDYEKQQFYNLTVRAKDKGRPVSLSSVSFVEVEVVD 1034 Query: 250 VNDN--APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 VN+N P F SV EN IG S+++V A D D G + E+ Y++ D G Sbjct: 1035 VNENLHTPYFPDFAVVGSVKENSRIGTSVLQVTARDEDSGRDGEIQYSIRDGSGLGR--- 1091 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 +ID SG + + LDRET Y L V ATD G P +T Sbjct: 1092 -FSIDDESGVITAADILDRETMGSYWLTVYATDRGVVPLYSTIEVYIEVEDVNDNAPLTS 1150 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITV 425 Y + E+ P V+ + A D D + +L Y IT GN + F+I + G + T Sbjct: 1151 EPIYYPVVMENSPKDVSVIQIQAEDPDSSSNEKLTYRITSGNPQNFFAINIKTGL-ITTT 1209 Query: 426 AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFE--D 481 ++ LD +Q+ + L V+ TD G + T V + + D N+ P F Y + E Sbjct: 1210 SRKLDREQQAEHFLEVTVTDGGPSPKQSTIWVVVQVLDENDNKPQFPEKVYQIKLPERDR 1269 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 G + A D D G NA+I+YS+ + D +F I+P+TG +++ K + Sbjct: 1270 KKRGEPIYRAFAFDRDEGPNAEISYSIVD-------GNDDGKFFIDPKTGMVSSRK---Q 1319 Query: 542 ETMSGY-LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV---FKQQLYTANIMEDALVG 597 T Y +LT+ A D G P S T + I + P+ F + Y +ME V Sbjct: 1320 FTAGSYDILTIKAVDNGRPQKSSTARLHIEWIKKPPPSPIPLTFDEPFYNFTVMESDRVT 1379 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 V V A N + +++ + +F + G I K LD E + +++ Sbjct: 1380 EIVGVVSVQPA----NTPLWFDI-VGGNFDSAFDAEKGVGTIVIAKPLDAEQRSIYNMSV 1434 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 DG + V IK+ D ND+ P F ISE+ T I +I A D DE Sbjct: 1435 EVTDG---TNVAVTQVFIKVLDNNDNGPEFSQPNYDVTISEDVLPDTEILQIEATDRDE- 1490 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK-YELVIRAAS-PPLW 775 + Y++ DS S + R L T LD+E+ K +++R P Sbjct: 1491 -KHKLSYTVHSSIDSISMR-KFRIDPSTGVLYTAERLDHEAQDKHILNIMVRDQEFPYRR 1548 Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILS 833 N RV + V D ND++P + + ++ +V A D D + +L Y I + Sbjct: 1549 NLARVIVNVEDANDHSPYFTNPLYEASVFESAALGSAVLQVTALDKDKGENAELIYTIEA 1608 Query: 834 GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 GN N+ + G +T+ + + + + VTD Sbjct: 1609 GNTGNMFKIEPVLGIITICKEPDMTTMGQFVLSIKVTD 1646 Score = 287 bits (704), Expect = 3e-75 Identities = 249/877 (28%), Positives = 396/877 (45%), Gaps = 77/877 (8%) Query: 17 NDHSPVFEMQ-QYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDA 75 N P F+ + +V+E G +L +KA D D G N +V +TI D+ Sbjct: 720 NRQGPYFDKSFPSDVAVKEDLPVGANILKIKAYDADSGFNGKVLFTISDGNTDSC----- 774 Query: 76 XXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTAT 135 F ID +G L +DRE Y + + D +P + SS Sbjct: 775 --------------FNIDMETGQLKVLMPMDREHTDLYLLNITIYDLGNP---QKSSWRL 817 Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195 + +N+ D NDN P F + +Y+V++ E + I +++A D D+G+N + Y+++ + Sbjct: 818 LTINVEDANDNSPVFIQDSYSVNILESSGI--GTEIIQVEARDKDLGSNGEVTYSVL-TD 874 Query: 196 TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS--NTTQLLINIRDVNDN 253 TQ QF+I+S +G V + LD E +Y L I A+D + + L + + DVND Sbjct: 875 TQ-QFAINSSTGIVYVADQLDRESKANYSLKIEARDKAESGQQLFSVVTLKVFLDDVNDC 933 Query: 254 APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313 +P F S + V E++P+G I ++ +D D G+ ++ Y++ + DY G + ID Sbjct: 934 SPAFIPSSYSVKVLEDLPVGTVIAWLETHDPDLGLGGQVRYSLVN-DYNGRFE----IDK 988 Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXXXXFMPGQY 371 SG + S +LD E Q Y L V A D G P S + + P Sbjct: 989 ASGAIRLSKELDYEKQQFYNLTVRAKDKGRPVSLSSVSFVEVEVVDVNENLHTPYFPDFA 1048 Query: 372 EV-ELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 V + E+ GT V+ +TA D D D + Y I G+ GRFSI ++ G+IT A Sbjct: 1049 VVGSVKENSRIGTSVLQVTARDEDSGRDGEIQYSIRDGSGLGRFSIDDES--GVITAADI 1106 Query: 429 LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD + Y LTV ATD G T V I + D N+ AP+ Y V E++P Sbjct: 1107 LDRETMGSYWLTVYATDRGVVPLYSTIEVYIEVEDVNDNAPLTSEPIYYPVVMENSPKDV 1166 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKLLDRETMS 545 +V+ + A D D N ++TY ++S + F IN +TG I TT++ LDRE + Sbjct: 1167 SVIQIQAEDPDSSSNEKLTYRITS-------GNPQNFFAINIKTGLITTTSRKLDREQQA 1219 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME--DALVGTSVSQV 603 + L VT DGG T V + V+D NDN+P F +++Y + E G + + Sbjct: 1220 EHFLEVTVTDGGPSPKQSTIWVVVQVLDENDNKPQFPEKVYQIKLPERDRKKRGEPIYRA 1279 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV-AIDG 662 A D D G N I Y + ++G F IDP +G++ + K + ++D+ + A+D Sbjct: 1280 FAFDRDEGPNAEISYSI-VDGNDDGKFFIDPKTGMVSSRKQF---TAGSYDILTIKAVDN 1335 Query: 663 GTPPQSSTVIVHIKIEDINDSPP-----VFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 G P +SST +H IE I PP F+ F + E+ + +G + + Sbjct: 1336 GRPQKSSTARLH--IEWIKKPPPSPIPLTFDEPFYNFTVMESDRVTEIVGVVSV----QP 1389 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND 777 N + + I GG+ ++F E G+ +V LD E R Y + + Sbjct: 1390 ANTPLWFDIVGGNFDSAFDAEKGVGT----IVIAKPLDAEQ-RSIYNMSVEVTDGTNVAV 1444 Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNA 837 +V I V D NDN P +D P ++ A D D KL Y + S ++ Sbjct: 1445 TQVFIKVLDNNDNGPEFSQPNYDVTISEDVLPDTEILQIEATDRDEKHKLSYTVHSSIDS 1504 Query: 838 ---NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 ++ +TG + + +L+ + + V D Sbjct: 1505 ISMRKFRIDPSTGVLYTAERLDHEAQDKHILNIMVRD 1541 Score = 280 bits (686), Expect = 5e-73 Identities = 266/902 (29%), Positives = 415/902 (46%), Gaps = 83/902 (9%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 I I V D ND++P+ Y V E + +V+ ++A D D N ++ Y I Sbjct: 1133 IEVYIEVEDVNDNAPLTSEPIYYPVVMENSPKDVSVIQIQAEDPDSSSNEKLTYRIT--- 1189 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRA-SLDREKVARYTVLVKATDQASP 125 + NP Q+ F I+ ++G + T + LDRE+ A + + V TD P Sbjct: 1190 --SGNP--------------QNFFAINIKTGLITTTSRKLDREQQAEHFLEVTVTD-GGP 1232 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 + ST + V ++D+NDN PQF EK Y + + E I + A D D G N+ Sbjct: 1233 SPKQ--STIWVVVQVLDENDNKPQFPEKVYQIKLPERDRKKRGEPIYRAFAFDRDEGPNA 1290 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR-LVIRAQDGGSPSRSNTTQLL 244 I Y+I+ GN +F ID +G VS K SY L I+A D G P +S+T +L Sbjct: 1291 EISYSIVDGNDDGKFFIDPKTGMVSSRKQF---TAGSYDILTIKAVDNGRPQKSSTARL- 1346 Query: 245 INIRDVNDNAPRFYTSLFQES-VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 +I + P F E + V + + + + N L + + G Sbjct: 1347 -HIEWIKKPPPSPIPLTFDEPFYNFTVMESDRVTEIVGVVSVQPANTPLWFDIVG----G 1401 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 N D + G + + LD E ++ Y + V TDG A Sbjct: 1402 NFDSAFDAEKGVGTIVIAKPLDAEQRSIYNMSVEVTDG---TNVAVTQVFIKVLDNNDNG 1458 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG-NTRGRFSITSQNGRGL 422 F Y+V ++ED P T ++ + ATD DE ++L Y + ++ G+ Sbjct: 1459 PEFSQPNYDVTISEDVLPDTEILQIEATDRDEKHKLSYTVHSSIDSISMRKFRIDPSTGV 1518 Query: 423 ITVAQPLDFKQERRYVLTVSATDS--GGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 + A+ LD + + +++L + D R + A V +N+ DAN+++P F N Y ASVFE Sbjct: 1519 LYTAERLDHEAQDKHILNIMVRDQEFPYRRNLARVIVNVEDANDHSPYFTNPLYEASVFE 1578 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 A +G+ VL V+A D D G NA++ Y++ E N F I P G IT K D Sbjct: 1579 SAALGSAVLQVTALDKDKGENAELIYTI--EAGNTG-----NMFKIEPVLGIITICKEPD 1631 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 TM ++L++ D G P +S T V ISV +++ P F + Y A + E+ +GTSV Sbjct: 1632 MTTMGQFVLSIKVTDQGSPPMSATAIVRISVTMSDNSHPKFIHKDYQAEVNENVDIGTSV 1691 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 + A + YE+ D G F I+P SGVI T KALD E +++ L A Sbjct: 1692 ILISAIS-----QSTLIYEVKDGD-INGIFTINPYSGVITTQKALDYERTSSYQLIIQAT 1745 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE-------IRAHD 713 + +S V+I+I D ND+ PVF + +SE +PI + + IRA D Sbjct: 1746 N--MAGMASNATVNIQIVDENDNAPVFLFSQYSGSLSEAAPINSIVRSLDNSPLVIRATD 1803 Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES-PRKKYELVIR-AAS 771 D NA++ Y I F++++ G+ + T+ +LD+E+ + + +R + S Sbjct: 1804 ADSNRNALLVYQIVESTAKKFFTVDSSTGA----IRTIANLDHETIAHFHFHVHVRDSGS 1859 Query: 772 PPLW--NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP--VG-PFGRVPAYDAD--VT 824 P L + V V I VTDVNDN PV Q +F P VG +V A D D V Sbjct: 1860 PQLTAESPVEVNIEVTDVNDNPPVFT--QAVFETIL-LLPTYVGVEVLKVSATDPDSEVP 1916 Query: 825 DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATM-EVSVTDGVNEIKAMMQLS 883 +L Y ++ G + + L++ +G +T+ N N+ K M V V+DG +M+ + Sbjct: 1917 PELTYSLMEG-SLDHFLIDSNSGVLTIK---NNNLSKDHYMLIVKVSDGKFYSTSMVTIM 1972 Query: 884 VR 885 V+ Sbjct: 1973 VK 1974 Score = 277 bits (680), Expect = 2e-72 Identities = 247/797 (30%), Positives = 370/797 (46%), Gaps = 63/797 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++N+ D ND+SPVF Y A+V+ A GT + + A D+D G N EV Y ++ Sbjct: 2072 RVNIEDINDNSPVFVGLPYYAAVQVDAEPGTLIYQVTAIDKDKGPNGEVTYVLQ------ 2125 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDRE-KVARYTVLVKATDQASPVSD 128 +D F I+ SG ++ + + + + Y V + A D P Sbjct: 2126 ---DDYGH------------FEINPNSGNVILKEAFNSDLSNIEYGVTILAKDGGKP--- 2167 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 LS++ + + I+ N P F + YT SV+EDI + N I I AT + I Sbjct: 2168 SLSTSVELPITIV--NKAMPVFDKPFYTASVNEDIRM--NTPILSINATSPE---GQGII 2220 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN-TTQLLINI 247 Y II G+ QF+ID +G + +V LDYE +Y+L IRA D + +R+ T LL+N Sbjct: 2221 YIIIDGDPFKQFNIDFDTGVLKVVSPLDYEVTSAYKLTIRASDALTGARAEVTVDLLVN- 2279 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 DVNDN P F + ++SE IG +++V + DAD N + Y + Y + D Sbjct: 2280 -DVNDNPPIFDQPTYNTTLSEASLIGTPVLQVVSIDADSENNKMVHYQIVQDTY-NSTDY 2337 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 ID SG + T+ LD E L V + D G P S+ F Sbjct: 2338 -FHIDSSSGLILTARMLDHELVQHCTLKVRSIDSGFPSLSSEVLVHIYISDVNDNPPVFN 2396 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITV 425 YE ++E P G V + A+DAD +RL Y I GN R F + S++ G+IT+ Sbjct: 2397 QLIYESYVSELAPRGHFVTCVQASDADSSDFDRLEYSILSGNDRTSFLMDSKS--GVITL 2454 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 + + E Y L VS +D G + TA V I + AN Y+P F + Y A V E+ G Sbjct: 2455 SNHRKQRMEPLYSLNVSVSD-GLFTSTAQVHIRVLGANLYSPAFSQSTYVAEVRENVAAG 2513 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET-M 544 T V+ V ATD D G QI+Y++ ++ + + +F+I+ G + T + LDRE + Sbjct: 2514 TKVIHVRATDGDPGTYGQISYAIINDFAKD-------RFLID-SNGQVITTERLDRENPL 2565 Query: 545 SGYL-LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 G + + V A DGG + T V + VVD NDN P F Y A++ D G V+QV Sbjct: 2566 EGDVSIFVRALDGGGRTTFCT--VRVIVVDENDNAPQFMTVEYRASVRADVGRGHLVTQV 2623 Query: 604 GATDADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 A D D G N RI Y L + IDP +G + T ++ A+D Sbjct: 2624 QAIDPDDGANSRITYSLYSEASVSVADLLEIDPDNGWMVTKGNFNQLKNTVLSFFVKAVD 2683 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 GG P + S + V+I + P F +F I+E++ IG+T+ +R + Sbjct: 2684 GGIPVKHSLIPVYIHVLPPETFLPSFTQSQYSFTIAEDTAIGSTVDTLRILPSQNVWFST 2743 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPRKKYEL--VIRAASPPLWNDV 778 V+ + F +E G+ K + LD E SP +++ I + V Sbjct: 2744 VNGERPENNKGGIFVIEQETGTIKLD----KRLDRETSPAFHFKVAATIPLDKVDIVFTV 2799 Query: 779 RVEILVTDVNDNAPVMK 795 V+I V D+NDN PV + Sbjct: 2800 DVDIKVLDLNDNKPVFE 2816 Score = 276 bits (677), Expect = 6e-72 Identities = 237/792 (29%), Positives = 360/792 (45%), Gaps = 64/792 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTV-------LTLKATDQDIGKNAEVEYTIE 63 I ++D ND++PVF QY S+ E A + V L ++ATD D +NA + Y I Sbjct: 1758 IQIVDENDNAPVFLFSQYSGSLSEAAPINSIVRSLDNSPLVIRATDADSNRNALLVYQIV 1817 Query: 64 LVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQA 123 TA + F +D +GA+ T A+LD E +A + V D Sbjct: 1818 ESTA-------------------KKFFTVDSSTGAIRTIANLDHETIAHFHFHVHVRDSG 1858 Query: 124 SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183 SP S +++ + D NDN P F++ + + V + K+ ATD D Sbjct: 1859 SPQLTA-ESPVEVNIEVTDVNDNPPVFTQAVFETILLLPTYV--GVEVLKVSATDPDSEV 1915 Query: 184 NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 + Y+++ G+ F IDS SG V +K + + Y L+++ DG S S T Sbjct: 1916 PPELTYSLMEGSLD-HFLIDSNSG-VLTIKNNNLSKDH-YMLIVKVSDGKFYSTSMVT-- 1970 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA-DEGVNAELTYTMTDKDYT 302 I +++ D+ F S + S+SEN +I +V +A +N L Y++ + Sbjct: 1971 -IMVKEAMDSGLHFTQSFYSTSISEN---NTNITKVAIVNAVGNRLNEPLKYSILNP--- 2023 Query: 303 GNVDLPITIDPRSGWVYTSG-QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 GN I SG + T+G DRE Q Y+L+V A+ D R A Sbjct: 2024 GN---KFKIKSTSGVIQTTGVPFDREEQELYELVVEASRELDHLRVARVVVRVNIEDIND 2080 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421 F+ Y + D PGT + +TA D D+ + G F I +G Sbjct: 2081 NSPVFVGLPYYAAVQVDAEPGTLIYQVTAIDKDKGPNGEVTYVLQDDYGHFEINPNSGNV 2140 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 ++ A D Y +T+ A D G S + V++ IT N PVF+ YTASV ED Sbjct: 2141 ILKEAFNSDLSNIE-YGVTILAKDGGKPSLSTSVELPITIVNKAMPVFDKPFYTASVNED 2199 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 + T +L ++AT + I Y + I + +QF I+ TG + LD Sbjct: 2200 IRMNTPILSINATSPE---GQGIIYII---IDGDPF----KQFNIDFDTGVLKVVSPLDY 2249 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 E S Y LT+ A D + ++ T V++ V DVNDN P+F Q Y + E +L+GT V Sbjct: 2250 EVTSAYKLTIRASDALTGARAEVT-VDLLVNDVNDNPPIFDQPTYNTTLSEASLIGTPVL 2308 Query: 602 QVGATDADVGLNGRIHYEL-DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 QV + DAD N +HY++ F ID +SG+I T + LD E V LK +I Sbjct: 2309 QVVSIDADSENNKMVHYQIVQDTYNSTDYFHIDSSSGLILTARMLDHELVQHCTLKVRSI 2368 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 D G P SS V+VHI I D+ND+PPVF Y+SE +P G + ++A D D Sbjct: 2369 DSGFPSLSSEVLVHIYISDVNDNPPVFNQLIYESYVSELAPRGHFVTCVQASDADSSDFD 2428 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRV 780 + YSI G+D SF ++++ G ++T+ + + Y L + + + +V Sbjct: 2429 RLEYSILSGNDRTSFLMDSKSG-----VITLSNHRKQRMEPLYSLNVSVSDGLFTSTAQV 2483 Query: 781 EILVTDVNDNAP 792 I V N +P Sbjct: 2484 HIRVLGANLYSP 2495 Score = 248 bits (608), Expect = 1e-63 Identities = 167/518 (32%), Positives = 267/518 (51%), Gaps = 37/518 (7%) Query: 372 EVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 +V + ED P G ++ + A DAD + ++ + I+ GNT F+I + G+ + V P+ Sbjct: 733 DVAVKEDLPVGANILKIKAYDADSGFNGKVLFTISDGNTDSCFNIDMETGQ--LKVLMPM 790 Query: 430 DFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 D + Y+L ++ D G +S ++ IN+ DAN+ +PVF Y+ ++ E + IGT Sbjct: 791 DREHTDLYLLNITIYDLGNPQKSSWRLLTINVEDANDNSPVFIQDSYSVNILESSGIGTE 850 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 ++ V A D D+G N ++TYS+ ++ QQF IN TG + LDRE+ + Y Sbjct: 851 IIQVEARDKDLGSNGEVTYSVLTD---------TQQFAINSSTGIVYVADQLDRESKANY 901 Query: 548 LLTVTARDGGV--PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 L + ARD L +++ + DVND P F Y+ ++ED VGT ++ + Sbjct: 902 SLKIEARDKAESGQQLFSVVTLKVFLDDVNDCSPAFIPSSYSVKVLEDLPVGTVIAWLET 961 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 D D+GL G++ Y L + G F ID ASG IR +K LD E ++L A D G P Sbjct: 962 HDPDLGLGGQVRYSL--VNDYNGRFEIDKASGAIRLSKELDYEKQQFYNLTVRAKDKGRP 1019 Query: 666 PQSSTV-IVHIKIEDINDS--PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 S+V V +++ D+N++ P F + + ENS IGT++ ++ A D D G + + Sbjct: 1020 VSLSSVSFVEVEVVDVNENLHTPYFPDFAVVGSVKENSRIGTSVLQVTARDEDSGRDGEI 1079 Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVR 779 YSI+ G FS++ D++ ++T D+ Y L + A PL++ + Sbjct: 1080 QYSIRDGSGLGRFSID-----DESGVITAADILDRETMGSYWLTVYATDRGVVPLYSTIE 1134 Query: 780 VEILVTDVNDNAPVMKD---FQIIF-NNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGN 835 V I V DVNDNAP+ + + ++ N+ KD + P D+ +KL YRI SGN Sbjct: 1135 VYIEVEDVNDNAPLTSEPIYYPVVMENSPKDVSVIQIQAEDP--DSSSNEKLTYRITSGN 1192 Query: 836 NANLILLNETTGSM-TLSPQLNTNVPKLATMEVSVTDG 872 N +N TG + T S +L+ +EV+VTDG Sbjct: 1193 PQNFFAINIKTGLITTTSRKLDREQQAEHFLEVTVTDG 1230 Score = 191 bits (466), Expect = 2e-46 Identities = 174/594 (29%), Positives = 277/594 (46%), Gaps = 51/594 (8%) Query: 103 ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162 A L+RE Y ++VK + + + L + +++ ++D ND P FS TY+V++ E Sbjct: 116 AILNREIQDNYLLIVKGSVRG----EDLEAWTKVNIQVLDMNDLRPLFSPTTYSVTIAES 171 Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222 + + +A++ ATDAD+G+N Y N FS+ SG +SL L+Y++ Sbjct: 172 TPLRTS--VAQVTATDADIGSNGEFYYYF--KNKVDLFSVHPTSGVISLSGRLNYDEKNR 227 Query: 223 YRLVIRAQDG-----GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277 Y L I A D G+ S+T +L ++I +N++AP + E P Y++V Sbjct: 228 YDLEILAVDRGMKLYGNNGVSSTAKLYVHIERINEHAPTIHVVTHVPFSLEKEPT-YAVV 286 Query: 278 RVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW-----VYTSGQLDRET-QAK 331 V D D+G N E+ G+ + W + Q+D E+ Sbjct: 287 TVD--DLDDGANGEIESVSI---VAGDPLDQFFLAKEGKWLNEYKIKERKQIDWESFPYG 341 Query: 332 YQLLVTATDGGDPPR-SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTA 390 Y L + A D G P + SA F Y+V ++E PPG V + Sbjct: 342 YNLTLQAKDKGSPQKCSALKAVYIGNPTRDTVPIRFEKEVYDVSISEFSPPGVVVAIVKL 401 Query: 391 TDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS 450 + D + Y+++ G F I ++ GLI A+PL+ ++ Y L V+ + + Sbjct: 402 SPEPID--VEYKLSPGEDAVYFKINPRS--GLIVTARPLNTVKKEVYKLEVTNKEGDLK- 456 Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510 A V I+I DAN++ P F+ Y A V E P+GT+VL VSA+D D G N ITYS++S Sbjct: 457 --AQVTISIEDANDHTPEFQQPLYDAYVNESVPVGTSVLTVSASDKDKGENGYITYSIAS 514 Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG-YLLTVTARDGGVPSLSDT-TDVE 568 + FVIN TG I+T + LD E+ Y V A D G P ++ +V Sbjct: 515 --------LNLLPFVINQFTGVISTTEELDFESSPEIYRFIVRASDWGSPYRHESEVNVT 566 Query: 569 ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG 628 I + +VNDN P+F++ I D VG ++ V A D D + Y++ E G Sbjct: 567 IRIGNVNDNSPLFEKVACQGVISYDFPVGGHITAVSAIDIDE--LELVKYKI-ISGNELG 623 Query: 629 SFVIDPASGVIRTNKALDRESVATHD--LKAVAIDG---GTPPQSSTVIVHIKI 677 F ++P SGV++ K+L + + L+ A DG P + ++H K+ Sbjct: 624 FFYLNPDSGVLQLKKSLTNSGIKNGNFALRITATDGENLADPMSINISVLHGKV 677 Score = 182 bits (442), Expect = 2e-43 Identities = 132/437 (30%), Positives = 215/437 (49%), Gaps = 30/437 (6%) Query: 463 NNYAPVFENA-PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521 N P F+ + P +V ED P+G +L + A D+D G N ++ +++S + D Sbjct: 720 NRQGPYFDKSFPSDVAVKEDLPVGANILKIKAYDADSGFNGKVLFTISD-------GNTD 772 Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581 F I+ +TG + +DRE YLL +T D G P S + I+V D NDN PVF Sbjct: 773 SCFNIDMETGQLKVLMPMDREHTDLYLLNITIYDLGNPQKSSWRLLTINVEDANDNSPVF 832 Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641 Q Y+ NI+E + +GT + QV A D D+G NG + Y + ++ F I+ ++G++ Sbjct: 833 IQDSYSVNILESSGIGTEIIQVEARDKDLGSNGEVTYSVLTDTQQ---FAINSSTGIVYV 889 Query: 642 NKALDRESVATHDLKAVAIDGGTPPQS--STVIVHIKIEDINDSPPVFESDCLTFYISEN 699 LDRES A + LK A D Q S V + + ++D+ND P F + + E+ Sbjct: 890 ADQLDRESKANYSLKIEARDKAESGQQLFSVVTLKVFLDDVNDCSPAFIPSSYSVKVLED 949 Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759 P+GT I + HDPD G V YS+ D + F ++ G+ + +LDYE Sbjct: 950 LPVGTVIAWLETHDPDLGLGGQVRYSLV-NDYNGRFEIDKASGAIRLS----KELDYEK- 1003 Query: 760 RKKYELVIRA---ASPPLWNDVR-VEILVTDVNDN--APVMKDFQIIFNNYKDCFPVG-P 812 ++ Y L +RA P + V VE+ V DVN+N P DF ++ + K+ +G Sbjct: 1004 QQFYNLTVRAKDKGRPVSLSSVSFVEVEVVDVNENLHTPYFPDFAVV-GSVKENSRIGTS 1062 Query: 813 FGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVT 870 +V A D D ++QY I G+ +++ +G +T + L+ + V T Sbjct: 1063 VLQVTARDEDSGRDGEIQYSIRDGSGLGRFSIDDESGVITAADILDRETMGSYWLTVYAT 1122 Query: 871 D-GVNEIKAMMQLSVRL 886 D GV + + +++ + + Sbjct: 1123 DRGVVPLYSTIEVYIEV 1139 Score = 163 bits (395), Expect = 8e-38 Identities = 164/599 (27%), Positives = 263/599 (43%), Gaps = 48/599 (8%) Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380 S L+RE Q Y L+V + G+ + T F P Y V +AE P Sbjct: 115 SAILNREIQDNYLLIVKGSVRGEDLEAWTKVNIQVLDMNDLRPL-FSPTTYSVTIAESTP 173 Query: 381 PGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440 T V +TATDAD + + N FS+ +G +I+++ L++ ++ RY L Sbjct: 174 LRTSVAQVTATDADIGSNGEFYYYFKNKVDLFSVHPTSG--VISLSGRLNYDEKNRYDLE 231 Query: 441 VSATDSG-------GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 + A D G G S TA + ++I N +AP + E P T VV+ Sbjct: 232 ILAVDRGMKLYGNNGVSSTAKLYVHIERINEHAPTIHVVTHVPFSLEKEP---TYAVVTV 288 Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP----QTGAITTNKLLDRETMS-GYL 548 D D G N +I +S A DQ F+ I K +D E+ GY Sbjct: 289 DDLDDGANGEI-----ESVSIVAGDPLDQFFLAKEGKWLNEYKIKERKQIDWESFPYGYN 343 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPV-FKQQLYTANIMEDALVGTSVSQVGATD 607 LT+ A+D G P D P+ F++++Y +I E + G V+ V + Sbjct: 344 LTLQAKDKGSPQKCSALKAVYIGNPTRDTVPIRFEKEVYDVSISEFSPPGVVVAIVKLSP 403 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 + + Y+L P + + F I+P SG+I T + L+ + L+ +G Q Sbjct: 404 EPID----VEYKLSPGE-DAVYFKINPRSGLIVTARPLNTVKKEVYKLEVTNKEGDLKAQ 458 Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 V I IED ND P F+ Y++E+ P+GT++ + A D D+G N + YSI Sbjct: 459 -----VTISIEDANDHTPEFQQPLYDAYVNESVPVGTSVLTVSASDKDKGENGYITYSIA 513 Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLW-NDVRVEIL 783 N Q + + T +LD+ES + Y ++RA+ SP ++V V I Sbjct: 514 ---SLNLLPFVINQFT--GVISTTEELDFESSPEIYRFIVRASDWGSPYRHESEVNVTIR 568 Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPAYDADVTDKLQYRILSGNNANLILL 842 + +VNDN+P+ + D FPV G V A D D + ++Y+I+SGN L Sbjct: 569 IGNVNDNSPLFEKVACQGVISYD-FPVGGHITAVSAIDIDELELVKYKIISGNELGFFYL 627 Query: 843 NETTGSMTLSPQLNTNVPKLA--TMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVR 899 N +G + L L + K + ++ TDG N + M +++ ++ ++ S + R Sbjct: 628 NPDSGVLQLKKSLTNSGIKNGNFALRITATDGEN-LADPMSINISVLHGKVSSKSFSCR 685 Score = 131 bits (317), Expect = 2e-28 Identities = 150/580 (25%), Positives = 245/580 (42%), Gaps = 71/580 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I VLD ND P+F Y ++ E T+V + ATD DIG N E Y + Sbjct: 147 IQVLDMNDLRPLFSPTTYSVTIAESTPLRTSVAQVTATDADIGSNGEFYYYFKNKV---- 202 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV--SD 128 D+F + SG + L+ ++ RY + + A D+ + ++ Sbjct: 203 -----------------DLFSVHPTSGVISLSGRLNYDEKNRYDLEILAVDRGMKLYGNN 245 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 +SSTA ++V+I N++ P T V S+ P A + D D GAN I Sbjct: 246 GVSSTAKLYVHIERINEHAP-----TIHVVTHVPFSLEKEPTYAVVTVDDLDDGANGEIE 300 Query: 189 -YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV------RSYRLVIRAQDGGSPSRSNTT 241 +I+ G+ QF + ++ K + +Q+ Y L ++A+D GSP + + Sbjct: 301 SVSIVAGDPLDQFFLAKEGKWLNEYKIKERKQIDWESFPYGYNLTLQAKDKGSPQKCSAL 360 Query: 242 QLLINIRDVNDNAP-RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 + + D P RF ++ S+SE P G + V+ + E ++ E Y ++ Sbjct: 361 KAVYIGNPTRDTVPIRFEKEVYDVSISEFSPPGVVVAIVKL--SPEPIDVE--YKLS--- 413 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 G + I+PRSG + T+ L+ + Y+L VT +G A Sbjct: 414 -PGEDAVYFKINPRSGLIVTARPLNTVKKEVYKLEVTNKEG-----DLKAQVTISIEDAN 467 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQN 418 F Y+ + E P GT V+T++A+D D E+ + Y I N Sbjct: 468 DHTPEFQQPLYDAYVNESVPVGTSVLTVSASDKDKGENGYITYSIASLNL---LPFVINQ 524 Query: 419 GRGLITVAQPLDFKQERR-YVLTVSATDSGG--RSDTAM-VQINITDANNYAPVFENAPY 474 G+I+ + LDF+ Y V A+D G R ++ + V I I + N+ +P+FE Sbjct: 525 FTGVISTTEELDFESSPEIYRFIVRASDWGSPYRHESEVNVTIRIGNVNDNSPLFEKVAC 584 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 + D P+G + VSA D D + Y + S NE F +NP +G + Sbjct: 585 QGVISYDFPVGGHITAVSAIDIDE--LELVKYKIIS--GNEL-----GFFYLNPDSGVLQ 635 Query: 535 TNKLLDRETM--SGYLLTVTARDGGVPSLSDTTDVEISVV 572 K L + + L +TA DG +L+D + ISV+ Sbjct: 636 LKKSLTNSGIKNGNFALRITATDG--ENLADPMSINISVL 673 Score = 119 bits (286), Expect = 1e-24 Identities = 117/453 (25%), Positives = 200/453 (44%), Gaps = 28/453 (6%) Query: 443 ATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502 AT S G T + + T + A V+EN+ V + +G T++ +S D+ Sbjct: 28 ATVSQGLPGTGPLGFHFTHSIYNATVYENSAARTYVNSQSRMGITLIDLSW---DIKYRI 84 Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 ++ E V D F+ G + +L+RE YLL V G L Sbjct: 85 -VSGDEEGFFKAEEVIIADFCFLRIRTKGG--NSAILNREIQDNYLLIVKGSVRG-EDLE 140 Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP 622 T V I V+D+ND P+F Y+ I E + TSV+QV ATDAD+G NG +Y Sbjct: 141 AWTKVNIQVLDMNDLRPLFSPTTYSVTIAESTPLRTSVAQVTATDADIGSNGEFYYYFKN 200 Query: 623 KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG-----GTPPQSSTVIVHIKI 677 K F + P SGVI + L+ + +DL+ +A+D G SST +++ I Sbjct: 201 K---VDLFSVHPTSGVISLSGRLNYDEKNRYDLEILAVDRGMKLYGNNGVSSTAKLYVHI 257 Query: 678 EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH-YSIKGGDDSNSFS 736 E IN+ P + E P T + D D+G N + SI GD + F Sbjct: 258 ERINEHAPTIHVVTHVPFSLEKEP---TYAVVTVDDLDDGANGEIESVSIVAGDPLDQFF 314 Query: 737 LETRQGS--DKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNA 791 L ++G ++ ++ +D+ES Y L ++A SP + ++ + D Sbjct: 315 L-AKEGKWLNEYKIKERKQIDWESFPYGYNLTLQAKDKGSPQKCSALKAVYIGNPTRDTV 373 Query: 792 PVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTL 851 P+ + ++ + + P G + + D ++Y++ G +A +N +G + Sbjct: 374 PIRFEKEVYDVSISEFSPPGVVVAIVKLSPEPID-VEYKLSPGEDAVYFKINPRSGLIVT 432 Query: 852 SPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884 + LNT ++ +EV+ +G ++KA + +S+ Sbjct: 433 ARPLNTVKKEVYKLEVTNKEG--DLKAQVTISI 463 Score = 50.4 bits (115), Expect = 7e-04 Identities = 80/349 (22%), Positives = 127/349 (36%), Gaps = 45/349 (12%) Query: 1304 NGTLAGCPEKRSRCSSAPCYNGAECSDLWDT---YICDCKEGHTGKDCADSTGPPWRFGG 1360 NG L CP C PC +C + ++C C G G +C+ T F G Sbjct: 3789 NGGL--CPGSNDPCVEKPCPGDMQCVSYEASRRPFLCQCPPGKLG-ECSGHTS--LSFAG 3843 Query: 1361 DGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMSIQLKSGLLHYSYNGETMY-------- 1412 + + + + + AL +RT Q + +M + ++ +G+ + Sbjct: 3844 NSYIKYRLSENSKEEDFKLALRLRTLQSNGIIMYTRANPCIILKIVDGKLWFQLDCGSGP 3903 Query: 1413 ----LPMATLSDGAWHRI--EIKWLGTDISVTVDY--GLRTVLMPMLANKIQGQYIGKIL 1464 + ++DG+WH + E+ T +S+ Y R L + Y G ++ Sbjct: 3904 GILGISGRAVNDGSWHSVFLELNRNFTSLSLDDSYVERRRAPLYFQTLSTESSIYFGALV 3963 Query: 1465 IGG--LDTTAGLLASDVGFFEGCIQDVRIGTAQSLLN--RPTVRENV-----RDGCQSRA 1515 T + + F+GC+ V + + L R + E V + GC Sbjct: 3964 QADNIRSLTDTRVTQVLSGFQGCLDSVILNNNELPLQNKRSSFAEVVGLTELKLGCVLYP 4023 Query: 1516 D-CMLSICPPYSKCVTSWDSS--TCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTP 1568 D C S C C T S CTC + G C ++AC PC C D Sbjct: 4024 DACKRSPCQHGGSC-TGLPSGGYQCTCLSQFTGRNCESEITACFPNPCRNGGSC--DPIG 4080 Query: 1569 KGYSCACEPGYTLTT--SGCIESGKEECPGGWWGGSACGPCACDVTRGY 1615 + C C+ G T T E +EEC G + G C+ T GY Sbjct: 4081 NTFICNCKAGLTGVTCEEDINECEREECENGGSCVNVFGSFLCNCTPGY 4129 Score = 48.0 bits (109), Expect = 0.004 Identities = 46/197 (23%), Positives = 88/197 (44%), Gaps = 11/197 (5%) Query: 680 INDSPPVFESDCLT-FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738 IN P F+ + + E+ P+G I +I+A+D D G N V ++I G+ + F+++ Sbjct: 719 INRQGPYFDKSFPSDVAVKEDLPVGANILKIKAYDADSGFNGKVLFTISDGNTDSCFNID 778 Query: 739 TRQGSDKAELVTMVDLDYE-SPRKKYELVIRAASPPLWNDVR-VEILVTDVNDNAPVMKD 796 G +L ++ +D E + + I P + R + I V D NDN+PV Sbjct: 779 METG----QLKVLMPMDREHTDLYLLNITIYDLGNPQKSSWRLLTINVEDANDNSPVFIQ 834 Query: 797 FQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQ 854 N + +V A D D+ ++ Y +L+ + +N +TG + ++ Q Sbjct: 835 DSYSVNILESSGIGTEIIQVEARDKDLGSNGEVTYSVLT--DTQQFAINSSTGIVYVADQ 892 Query: 855 LNTNVPKLATMEVSVTD 871 L+ ++++ D Sbjct: 893 LDRESKANYSLKIEARD 909 Score = 39.5 bits (88), Expect = 1.3 Identities = 12/39 (30%), Positives = 22/39 (56%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C E + C C NG C +++ +++C+C G+ G+ C Sbjct: 4096 CEEDINECEREECENGGSCVNVFGSFLCNCTPGYVGQYC 4134 >UniRef50_A7S3G3 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 4187 Score = 429 bits (1056), Expect = e-118 Identities = 396/1357 (29%), Positives = 620/1357 (45%), Gaps = 120/1357 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND +P F Y AS+ E G+ VL + A D D G N V Y LV+ D L Sbjct: 2744 VQVLDINDVTPKFVSDPYLASIPENIDIGSKVLRVFAEDLDSGSNGMVTYA--LVSKDKL 2801 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 V++ F ID +G + TR +LDREK + V+ATD + RL Sbjct: 2802 ---------------VKEKFDIDQHTGWITTRGALDREKQPSFEFQVRATDNGTT---RL 2843 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +S T+ ++D ND P+FS+ + SV ED + + + I ATD D+ N+ + Y Sbjct: 2844 TSLTTVRAIVLDVNDTPPKFSQSEFMASVKEDALIGQS--VTTITATDEDL--NTELYYF 2899 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I+ G+ Q +F I+ +G + + +LD E V SY L I A DG S + Q+ I+I D Sbjct: 2900 ILSGDPQARFGIERKTGVIFVHGSLDRESVGSYDLNISASDGLFTSFA---QMKIDIEDA 2956 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P S++ E + EN P+G +++ V A DAD GVNAELTY++ + + Sbjct: 2957 NDNPPICTQSIYVEHIKENTPLGSTVLTVGATDADVGVNAELTYSVFGQGFG-----TFA 3011 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 +D ++G + +LDRET+ Y +V+A D G ++ + F Sbjct: 3012 VD-KNGKMTNLVELDRETRPFYNFMVSAADIGG--QACYSNISIHLDDVNDNRPLFSQSS 3068 Query: 371 YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 Y + ED P ++ + A DAD + +L Y + + G F+I + G G+I++ +P Sbjct: 3069 YFTAVYEDAPLKKVLLQVKADDADVGVNRKLTYSLVT-DAGGTFTI--ETGTGIISLEKP 3125 Query: 429 LDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 L+ + + Y L V D G S A VQI + + N+ P F ++ Y +V EDAPIG Sbjct: 3126 LNRELKENYTLNVEVMDGGTPPLSSIATVQIKVLNINDVPPEFSHSIYHGNVSEDAPIGN 3185 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 V+ V A + N ITY++ + F I+ + G I N+ LD ET Sbjct: 3186 EVVRVRAVSRESS-NDVITYAILRGADSGL-------FSIDRKNGTIHVNRKLDYETTKL 3237 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y LTV A D G P L T+ V ISV D NDN P F ++ Y+A + E++ +GT V QV AT Sbjct: 3238 YTLTVEASDAGPPVLRSTSYVRISVTDSNDNGPEFSEKRYSAKVDENSALGTFVLQVFAT 3297 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D D G N +I Y + + + F I +GVI+ + +DRE VA++ LK A D G PP Sbjct: 3298 DRDSGTNAQIKYSI-AEGNDAKKFKIVEETGVIKVSGDIDREEVASYRLKVRAQDQGLPP 3356 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE-GPNAVVHYS 725 Q + +V I++ D+ND+ P F S LT +SE+S + +R HD D G A ++ Sbjct: 3357 QVADTVVDIEVTDVNDNSPEFSSTNLTTVLSESSLPNAAVIHLRPHDRDALGNGAPYQFT 3416 Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVT 785 + GD S F L + K V+ D Y + LV PP +V + + + Sbjct: 3417 LISGDASR-FKLHSNGLITKIGDVSHSDGQY----RLRVLVADNGHPPQSTEVSITVKIA 3471 Query: 786 DVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNET 845 + + P + + N Y G GRV A D D D L Y ++S ++L+++++ Sbjct: 3472 ESKTHPPNVHPLTVYVNLYGSNLNGGVIGRVKATDKD-GDLLHYSLVSSEQSSLLMISD- 3529 Query: 846 TGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTA 905 T+ + N + P + VSVTD + + + + V IT E +S+T+RL D++A Sbjct: 3530 --EGTVRARANIS-PGTYNLNVSVTDKRYTVYSGVTVIVLNITPETQEHSVTLRLGDLSA 3586 Query: 906 EQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGD 965 F+ L + + ++ P NI+++S+Q + N L+V + R+ G+ Sbjct: 3587 GTFVEKSLEKCLLFIGKLLDVPAVNIHVWSMQP----SDNDLDVVIAVRK--RRKGM--- 3637 Query: 966 PSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGF 1025 + P +L ++ + V+++ + C + C + C V K Sbjct: 3638 ----FKPLYLTRQLNGSHLAFEKNVGVRIVTVGLSQCRAQDCPTYLVCSDVYKPELKQIR 3693 Query: 1026 VNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG 1085 V SD V + S +C C + G C I A+ S C G +C E Sbjct: 3694 VMSDHVSYISYEHSRSHSCTCQDKNRG--CGAIQKCAT-------SPCAPGYKCKDFPE- 3743 Query: 1086 GILCQGCSIDAAYTTAVCELRARSFPVSSFLTFPGLKR---RHRIHLKLKFATQTTSGLL 1142 G C+ C + + AR+F S++ + LK + + L T + G L Sbjct: 3744 GYQCK-CPL-----FHILGNNARTFNGDSYIRY-RLKETFDQPSRSIGLALKTVKSEGTL 3796 Query: 1143 LYNGRYNERHDFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGN-VGDGSWHTVEI 1201 ++ ++D+ LE+ G LRF F G G ++++ + V DG WH V + Sbjct: 3797 VFAA---GQYDYSILEISK------GFIQLRFDF--GSGPGVVSIDWSPVNDGKWHHVAV 3845 Query: 1202 EYFNRTITMILDDCDKVLSLAGAADFGLKYACAN---FTRKVLPARCEIPTETCHRFLDL 1258 E T+ LD S + N F KVL +R + + Sbjct: 3846 ERQGNHATVTLDYGKHQASGKSPGRMRILNLDGNSIYFGAKVLNSRI--------KRSEG 3897 Query: 1259 TGPLQIGGLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCS 1318 G + G + V KD S+ Y + T + C+ Sbjct: 3898 QGVIVENGFKGCMQNLNVNGKDLPMTGSNTYASGYPSNAELSTGTFWTRLQ-SDYVGACA 3956 Query: 1319 SAPCYNGAEC-SDLWDTYICDCKEGHTGKDCADSTGP 1354 S+PC NG C + D +ICDC +G +GK C + P Sbjct: 3957 SSPCRNGGSCLAGQHDDFICDCPKGVSGKTCEVDSRP 3993 Score = 366 bits (901), Expect = 4e-99 Identities = 268/864 (31%), Positives = 422/864 (48%), Gaps = 71/864 (8%) Query: 5 FCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIEL 64 FC+ +++++D ND+ P+FE++ Y+ ++ + GT VL A+D D NA + Y I Sbjct: 2532 FCV-VEVHLIDENDNQPIFELKNYDTTISRSVTMGTPVLMTSASDPDASSNAALTYVI-- 2588 Query: 65 VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDRE-KVARYTVLVKATDQA 123 VF I+ +G + + RE +V Y V D Sbjct: 2589 -----------------VGHQTPPVFTINAATGVI----QVSREPEVKSYNFFVLVKDGG 2627 Query: 124 SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183 +P+ L S A++ + +++ + F + Y V+V E+ + ++ + G Sbjct: 2628 NPL---LRSIASVKITVLERDARILHFGKSKYDVTVGENAEM--GQIVTGLNLV-VPGGN 2681 Query: 184 NSAIRYAIIGG---NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240 + Y II G N +F +DS +G V ++ LDYE Y +++ A + + ++ Sbjct: 2682 PVDVDYRIIKGNNDNNDRKFGVDS-TGRVRVIGRLDYEIRNRYVMIVEA-NVSAINQIAR 2739 Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 T +++ + D+ND P+F + + S+ EN+ IG ++RV A D D G N +TY + KD Sbjct: 2740 TVVVVQVLDINDVTPKFVSDPYLASIPENIDIGSKVLRVFAEDLDSGSNGMVTYALVSKD 2799 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 V ID +GW+ T G LDRE Q ++ V ATD G ++ T Sbjct: 2800 KL--VKEKFDIDQHTGWITTRGALDREKQPSFEFQVRATDNGTTRLTSLTTVRAIVLDVN 2857 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420 F ++ + ED G V T+TATD D + L+Y I G+ + RF I + Sbjct: 2858 DTPPKFSQSEFMASVKEDALIGQSVTTITATDEDLNTELYYFILSGDPQARFGI--ERKT 2915 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 G+I V LD + Y L +SA+D G + A ++I+I DAN+ P+ + Y + E Sbjct: 2916 GVIFVHGSLDRESVGSYDLNISASD-GLFTSFAQMKIDIEDANDNPPICTQSIYVEHIKE 2974 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 + P+G+TVL V ATD+DVG+NA++TYS+ + F ++ + G +T LD Sbjct: 2975 NTPLGSTVLTVGATDADVGVNAELTYSVFGQGFG--------TFAVD-KNGKMTNLVELD 3025 Query: 541 RETMSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 RET Y V+A D GG S ++ I + DVNDN P+F Q Y + EDA + Sbjct: 3026 RETRPFYNFMVSAADIGGQACYS---NISIHLDDVNDNRPLFSQSSYFTAVYEDAPLKKV 3082 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 + QV A DADVG+N ++ Y L G+F I+ +G+I K L+RE + L Sbjct: 3083 LLQVKADDADVGVNRKLTYSL--VTDAGGTFTIETGTGIISLEKPLNRELKENYTLNVEV 3140 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 +DGGTPP SS V IK+ +IND PP F +SE++PIG + +RA E N Sbjct: 3141 MDGGTPPLSSIATVQIKVLNINDVPPEFSHSIYHGNVSEDAPIGNEVVRVRAVS-RESSN 3199 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA--ASPPLWND 777 V+ Y+I G DS FS++ + G+ + LDYE+ K Y L + A A PP+ Sbjct: 3200 DVITYAILRGADSGLFSIDRKNGT----IHVNRKLDYET-TKLYTLTVEASDAGPPVLRS 3254 Query: 778 VR-VEILVTDVNDNAPVMKD----FQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRIL 832 V I VTD NDN P + ++ N+ F + F D+ +++Y I Sbjct: 3255 TSYVRISVTDSNDNGPEFSEKRYSAKVDENSALGTFVLQVF--ATDRDSGTNAQIKYSIA 3312 Query: 833 SGNNANLILLNETTGSMTLSPQLN 856 GN+A + E TG + +S ++ Sbjct: 3313 EGNDAKKFKIVEETGVIKVSGDID 3336 Score = 353 bits (867), Expect = 5e-95 Identities = 288/895 (32%), Positives = 436/895 (48%), Gaps = 77/895 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND SPVF+ YE ++ E + G TV + A+D+D G N + Y I + Sbjct: 779 VKITDVNDCSPVFDKTVYEVTLPENITVGQTVTHVHASDKDQGTNGFITYQI-------V 831 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N FR++ SG + LD E+ Y + ++A D +S + ++ Sbjct: 832 NDFGGK-------------FRVNRISGVVSVGDYLDYEEQEMYKIEIQAMD-SSVDNQKV 877 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 ST I V ++D NDN P K + V+V ED+ V N V+ I A+D D G I ++ Sbjct: 878 GSTHVI-VTLLDINDNSPIVKPKKFNVTVQEDLLV--NAVVTSIHASDPDSGPGGEIEFS 934 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + + +F+IDS SG + L + LD+EQ +Y L +R D GSP+ ++++N+ DV Sbjct: 935 L--PESTRKFNIDSKSGVIRLRQRLDFEQKSTYNLTVRVTDKGSPALFTDVEVVVNVLDV 992 Query: 251 NDN--APRFYTS-LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 N+N AP F + + S++EN P+G ++ +A D D L Y + D TG VD Sbjct: 993 NENSLAPVFSGGRILETSINENSPVGTVVISPKATDQDSWY---LKYAIIDG--TG-VDK 1046 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 I IDP +G + T+G+LD E Y L V A DG P F Sbjct: 1047 FI-IDPDTGAIRTAGELDHEVADHYWLTVQAKDGESYPLYTNIPVLINIVDLNDEAPYFA 1105 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNRL-HYEITGGNTRGRFSITSQNGRGLITVA 426 P Y LAE+ P G+ VV +TA D D L Y IT GN + F I Q+G LIT Sbjct: 1106 PSTYYPVLAENLPSGSSVVQVTAKDPDSGGSLLRYTITKGNEQNNFVIDPQSG--LITTL 1163 Query: 427 QPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 +PLD + + Y LTVSA+D G S + ITD N+ P F+ Y VF Sbjct: 1164 RPLDREFKSEYKLTVSASDGGTPPVSTDVTFTVKITDENDNQPEFKEKQYVVGVFARQAT 1223 Query: 485 GTT--VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN-KLLDR 541 + + V ATD D+G NA + YS++ + D +F+I+ ++G I TN L+D Sbjct: 1224 SKSFGLYQVVATDEDIGSNADLRYSITK-------GNRDNKFIIDSRSGEIFTNVSLVDG 1276 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVND---NEPVFKQQLYTANIMEDALVGT 598 E+ Y LT+ A D G+P LS +T+V I V+ N N PVF + Y+A+I ED + + Sbjct: 1277 ES---YDLTIVAEDNGLPKLSTSTNVLIDVIQGNKPSKNAPVFWNKQYSADIQEDKRINS 1333 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 V +GA D D +I Y + F ID G I +LDRE + + L+ Sbjct: 1334 FVLIIGAEDPDFD---QITYNI-ASGNHGNKFTIDRYGGFITVAHSLDREEKSFYSLRVE 1389 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 A DG +++V V I I D+ND+ P +++ENS +GT + ++ DPD G Sbjct: 1390 ATDGYN---TASVPVTINILDVNDNSPQPARREYRAHVAENSDVGTLVTTVK--DPDAGV 1444 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLW 775 N V Y I + S SL + S ++T+ LDYE+ +++ L I+A+ P Sbjct: 1445 NGEVEYCIVQTAKAESASLFKIE-SHSGRILTVKPLDYET-MQEHVLTIKASDRGIPKRE 1502 Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG--RVPAYDAD--VTDKLQYRI 831 V + V DVND+ P +F + D RV A D D KL+Y I Sbjct: 1503 TLFSVVVSVDDVNDHKPEF--LSPLFESEVDVSAKAGTAILRVIATDKDDGTNSKLKYSI 1560 Query: 832 LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886 +SGN + +++ +G + ++ +L+T V + A S G +K + + V++ Sbjct: 1561 VSGNTNKSLSVDQNSGVVKVAGRLSTLVHQYALKVQSTDGGEPPLKTQVDVKVKV 1615 Score = 325 bits (799), Expect = 9e-87 Identities = 260/802 (32%), Positives = 392/802 (48%), Gaps = 80/802 (9%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 H + +LD ND+SP+ + +++ +V+E V ++ A+D D G E+E+++ Sbjct: 881 HVIVTLLDINDNSPIVKPKKFNVTVQEDLLVNAVVTSIHASDPDSGPGGEIEFSL----- 935 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 PE F ID +SG + R LD E+ + Y + V+ TD+ SP Sbjct: 936 ----PESTRK------------FNIDSKSGVIRLRQRLDFEQKSTYNLTVRVTDKGSPA- 978 Query: 128 DRLSSTATIHVNIIDDNDN--YPQFS-EKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184 L + + VN++D N+N P FS + S++E+ V V+ KATD D + Sbjct: 979 --LFTDVEVVVNVLDVNENSLAPVFSGGRILETSINENSPV--GTVVISPKATDQD---S 1031 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 ++YAII G +F ID +G + LD+E Y L ++A+DG S +L Sbjct: 1032 WYLKYAIIDGTGVDKFIIDPDTGAIRTAGELDHEVADHYWLTVQAKDGESYPLYTNIPVL 1091 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 INI D+ND AP F S + ++EN+P G S+V+V A D D G + L YT+T GN Sbjct: 1092 INIVDLNDEAPYFAPSTYYPVLAENLPSGSSVVQVTAKDPDSG-GSLLRYTIT----KGN 1146 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 IDP+SG + T LDRE +++Y+L V+A+DGG PP S T Sbjct: 1147 EQNNFVIDPQSGLITTLRPLDREFKSEYKLTVSASDGGTPPVSTDVTFTVKITDENDNQP 1206 Query: 365 XFMPGQYEVEL----AEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420 F QY V + A + G V T D + L Y IT GN +F I S++G Sbjct: 1207 EFKEKQYVVGVFARQATSKSFGLYQVVATDEDIGSNADLRYSITKGNRDNKFIIDSRSGE 1266 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDAN---NYAPVFENAPYT 475 + T +D + Y LT+ A D+G S + V I++ N APVF N Y+ Sbjct: 1267 -IFTNVSLVDGES---YDLTIVAEDNGLPKLSTSTNVLIDVIQGNKPSKNAPVFWNKQYS 1322 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 A + ED I + VL++ A D D QITY+++S +H +F I+ G IT Sbjct: 1323 ADIQEDKRINSFVLIIGAEDPDFD---QITYNIAS-------GNHGNKFTIDRYGGFITV 1372 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 LDRE S Y L V A DG + + V I+++DVNDN P ++ Y A++ E++ Sbjct: 1373 AHSLDREEKSFYSLRVEATDG---YNTASVPVTINILDVNDNSPQPARREYRAHVAENSD 1429 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGS--FVIDPASGVIRTNKALDRESVATH 653 VGT V+ V D D G+NG + Y + + E + F I+ SG I T K LD E++ H Sbjct: 1430 VGTLVTTV--KDPDAGVNGEVEYCIVQTAKAESASLFKIESHSGRILTVKPLDYETMQEH 1487 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713 L A D G P + + V + ++D+ND P F S + ++ GT I + A D Sbjct: 1488 VLTIKASDRGIPKRETLFSVVVSVDDVNDHKPEFLSPLFESEVDVSAKAGTAILRVIATD 1547 Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK--AELVTMVDLDYESPRKKYELVIRA-- 769 D+G N+ + YSI G+ + S S++ G K L T+V +Y L +++ Sbjct: 1548 KDDGTNSKLKYSIVSGNTNKSLSVDQNSGVVKVAGRLSTLV--------HQYALKVQSTD 1599 Query: 770 -ASPPLWNDVRVEILVTDVNDN 790 PPL V V++ V + N Sbjct: 1600 GGEPPLKTQVDVKVKVRGIVKN 1621 Score = 314 bits (772), Expect = 2e-83 Identities = 260/876 (29%), Positives = 411/876 (46%), Gaps = 74/876 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ ++D ND++P F+ Y AS+ AS G V + ATD D G ++ Y+I Sbjct: 2329 RVVLMDANDNAPRFDKSMYAASILGSASPGQFVTRILATDPDEGDAKKLRYSI------- 2381 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + F+ID +SG + + ++ Y + V+ +D Sbjct: 2382 ------------TGGQGRQHFQIDSQSGVITLSRVVGIKQGKVYGLDVEVSDSVH----- 2424 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 ST+ + V I D ND+ P FSE Y VS +E + + + + ATD D G + + Y Sbjct: 2425 -VSTSKVRVIIGDTNDHSPIFSEDVYKVSFNE--NYPEGTFVTMVSATDLDSGNYAHLTY 2481 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLV----IRAQDGGSPSRSNTTQLLI 245 +I + +F ID+ SG L L +++ S + + IRA DGG R + + Sbjct: 2482 SIDSVDAMRKFRIDADSG--MLYSRLMFDRENSSQAIMSVPIRATDGG--GRFGFCVVEV 2537 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 ++ D NDN P F + ++S +V +G ++ A D D NA LTY + G+ Sbjct: 2538 HLIDENDNQPIFELKNYDTTISRSVTMGTPVLMTSASDPDASSNAALTYVI-----VGHQ 2592 Query: 306 DLPI-TIDPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 P+ TI+ +G + Q+ RE + K Y V DGG+P + A+ Sbjct: 2593 TPPVFTINAATGVI----QVSREPEVKSYNFFVLVKDGGNPLLRSIASVKITVLERDARI 2648 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLT-ATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422 F +Y+V + E+ G V L + Y I GN + G Sbjct: 2649 LHFGKSKYDVTVGENAEMGQIVTGLNLVVPGGNPVDVDYRIIKGNNDNNDRKFGVDSTGR 2708 Query: 423 ITVAQPLDFKQERRYVLTVSATDSG-GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 + V LD++ RYV+ V A S + +V + + D N+ P F + PY AS+ E+ Sbjct: 2709 VRVIGRLDYEIRNRYVMIVEANVSAINQIARTVVVVQVLDINDVTPKFVSDPYLASIPEN 2768 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 IG+ VL V A D D G N +TY+L +S + + ++F I+ TG ITT LDR Sbjct: 2769 IDIGSKVLRVFAEDLDSGSNGMVTYAL---VSKDKLV--KEKFDIDQHTGWITTRGALDR 2823 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 E + V A D G L+ T V V+DVND P F Q + A++ EDAL+G SV+ Sbjct: 2824 EKQPSFEFQVRATDNGTTRLTSLTTVRAIVLDVNDTPPKFSQSEFMASVKEDALIGQSVT 2883 Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 + ATD D LN ++Y + D + F I+ +GVI + +LDRESV ++DL A D Sbjct: 2884 TITATDED--LNTELYYFILSGD-PQARFGIERKTGVIFVHGSLDRESVGSYDLNISASD 2940 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 G +S + I IED ND+PP+ +I EN+P+G+T+ + A D D G NA Sbjct: 2941 G---LFTSFAQMKIDIEDANDNPPICTQSIYVEHIKENTPLGSTVLTVGATDADVGVNAE 2997 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDV 778 + YS+ G +F+++ ++ +V+LD E+ R Y ++ AA ++++ Sbjct: 2998 LTYSV-FGQGFGTFAVD-----KNGKMTNLVELDRET-RPFYNFMVSAADIGGQACYSNI 3050 Query: 779 RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNN 836 + + DVNDN P+ Y+D +V A DAD V KL Y +++ + Sbjct: 3051 SIHL--DDVNDNRPLFSQSSYFTAVYEDAPLKKVLLQVKADDADVGVNRKLTYSLVT-DA 3107 Query: 837 ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 + TG ++L LN + + T+ V V DG Sbjct: 3108 GGTFTIETGTGIISLEKPLNRELKENYTLNVEVMDG 3143 Score = 306 bits (751), Expect = 6e-81 Identities = 233/756 (30%), Positives = 361/756 (47%), Gaps = 45/756 (5%) Query: 144 NDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSID 203 N ++P F + + E + V+++ ATD D G N + Y+I+ G+ F+I+ Sbjct: 680 NRHHPVFRSHDQNIHISESTPIAT--VVSQFMATDEDKGYNGLVLYSIVEGDVDSVFNIN 737 Query: 204 SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263 +G++++ LD E + SY L I A D G +S T L + I DVND +P F ++++ Sbjct: 738 MFTGELTVAMPLDRETISSYTLNISAVDCGKHRKSAYTILNVKITDVNDCSPVFDKTVYE 797 Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323 ++ EN+ +G ++ V A D D+G N +TY + + D+ G ++ SG V Sbjct: 798 VTLPENITVGQTVTHVHASDKDQGTNGFITYQIVN-DFGGK----FRVNRISGVVSVGDY 852 Query: 324 LDRETQAKYQLLVTATDGG-DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382 LD E Q Y++ + A D D + + P ++ V + ED Sbjct: 853 LDYEEQEMYKIEIQAMDSSVDNQKVGSTHVIVTLLDINDNSPIVKPKKFNVTVQEDLLVN 912 Query: 383 TPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 V ++ A+D D E + + +F+I S++ G+I + Q LDF+Q+ Y LTV Sbjct: 913 AVVTSIHASDPDSGPGGEIEFSLPESTRKFNIDSKS--GVIRLRQRLDFEQKSTYNLTVR 970 Query: 443 ATDSGGRS--DTAMVQINITDA--NNYAPVFENAP-YTASVFEDAPIGTTVLVVSATDSD 497 TD G + V +N+ D N+ APVF S+ E++P+GT V+ ATD D Sbjct: 971 VTDKGSPALFTDVEVVVNVLDVNENSLAPVFSGGRILETSINENSPVGTVVISPKATDQD 1030 Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG 557 + + Y++ I V +F+I+P TGAI T LD E Y LTV A+DG Sbjct: 1031 ---SWYLKYAI---IDGTGV----DKFIIDPDTGAIRTAGELDHEVADHYWLTVQAKDGE 1080 Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617 L V I++VD+ND P F Y + E+ G+SV QV A D D G + Sbjct: 1081 SYPLYTNIPVLINIVDLNDEAPYFAPSTYYPVLAENLPSGSSVVQVTAKDPDSG-GSLLR 1139 Query: 618 YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 Y + K E+ +FVIDP SG+I T + LDRE + + L A DGGTPP S+ V +KI Sbjct: 1140 YTI-TKGNEQNNFVIDPQSGLITTLRPLDREFKSEYKLTVSASDGGTPPVSTDVTFTVKI 1198 Query: 678 EDINDSPPVFESDCLTFYISENSPIGTTIG--EIRAHDPDEGPNAVVHYSIKGGDDSNSF 735 D ND+ P F+ + + G ++ A D D G NA + YSI G+ N F Sbjct: 1199 TDENDNQPEFKEKQYVVGVFARQATSKSFGLYQVVATDEDIGSNADLRYSITKGNRDNKF 1258 Query: 736 SLETRQGSDKAELVTMVDL-DYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVN--- 788 +++R G E+ T V L D ES Y+L I A P L V I V N Sbjct: 1259 IIDSRSG----EIFTNVSLVDGES----YDLTIVAEDNGLPKLSTSTNVLIDVIQGNKPS 1310 Query: 789 DNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGS 848 NAPV + Q + +D + F + + D++ Y I SGN+ N ++ G Sbjct: 1311 KNAPVFWNKQYSADIQED-KRINSFVLIIGAEDPDFDQITYNIASGNHGNKFTIDRYGGF 1369 Query: 849 MTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884 +T++ L+ ++ V TDG N + +++ Sbjct: 1370 ITVAHSLDREEKSFYSLRVEATDGYNTASVPVTINI 1405 Score = 301 bits (740), Expect = 1e-79 Identities = 241/811 (29%), Positives = 376/811 (46%), Gaps = 60/811 (7%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F ID G + SLDRE+ + Y++ V+ATD + S + +NI+D NDN PQ Sbjct: 1361 FTIDRYGGFITVAHSLDREEKSFYSLRVEATDGYNTAS------VPVTINILDVNDNSPQ 1414 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG---GNTQMQFSIDSLS 206 + + Y V E+ V ++ +K D D G N + Y I+ + F I+S S Sbjct: 1415 PARREYRAHVAENSDV--GTLVTTVK--DPDAGVNGEVEYCIVQTAKAESASLFKIESHS 1470 Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266 G + VK LDYE ++ + L I+A D G P R +++++ DVND+ P F + LF+ V Sbjct: 1471 GRILTVKPLDYETMQEHVLTIKASDRGIPKRETLFSVVVSVDDVNDHKPEFLSPLFESEV 1530 Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326 + G +I+RV A D D+G N++L Y++ +GN + +++D SG V +G+L Sbjct: 1531 DVSAKAGTAILRVIATDKDDGTNSKLKYSIV----SGNTNKSLSVDQNSGVVKVAGRLST 1586 Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386 +Y L V +TDGG+PP T F +YEV L E+ PP + Sbjct: 1587 LVH-QYALKVQSTDGGEPPLK-TQVDVKVKVRGIVKNFAFEKPKYEVSLPENSPPDQAIA 1644 Query: 387 TLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446 T+ YEI G + T Q G+I + D ++ L + A + Sbjct: 1645 TVVYNGI----LPVYEIVPGRSPCWRDFTVQRQSGVIISKKSFDAEEVTHCKLEIRANST 1700 Query: 447 GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV-------LVVSATDSDVG 499 G+ + +V + I D N+ P+FE+A T V E +P GT V LV ATD D+ Sbjct: 1701 DGQHSSTLVIVTIQDKNDNQPIFEHARITGHVTEGSPQGTAVLDHKGSQLVAVATDQDIS 1760 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 ++TY + + + F I+P TGAITT K+LD E Y + D G P Sbjct: 1761 -GDKLTYEIVETSARDV-------FSIHPATGAITTAKVLDYEVTPQYAFKIKVTDSGNP 1812 Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619 LS DV+I V D+ND PVF Y A + + GT V+ V ATD D N + + Sbjct: 1813 RLSAFADVKIHVTDINDIAPVFSASTYHATVYLPSYAGTRVTMVTATDGDSAAN--LTFS 1870 Query: 620 LDPKDREEGSFVIDPASGVIR-TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678 L +D E F ++P +GV+ +N AL R T+ +K DG ++ V I+ E Sbjct: 1871 LARQDTE--LFAVNPLTGVVTVSNAALLRRD--TYTIKLTVSDGN---HTAHARVRIRCE 1923 Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738 ++ S F + + E + + + +RA G + + Y+I + S F + Sbjct: 1924 NLPSSDLQFSRKNYSASVREGVSVDSELVTVRALGYPIG--STITYTII--NPSELFHIV 1979 Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMK 795 G + DLD ES Y+++++A + PP V + V D NDN PV Sbjct: 1980 PSTG--VMSIRAGFDLDRES-IDAYQVIVQARDDSVPPNVAQAAVHVQVIDRNDNQPVFI 2036 Query: 796 DFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRI-LSGNNANLILLNETTGSMTLSPQ 854 + G+ A DAD+ R L G + ++ TG + + Sbjct: 2037 NSPYFIVLQLGVAQGTIIGQAQATDADIGSNANLRYDLIGGDPGYFSISRKTGEVVVRRT 2096 Query: 855 L-NTNVPKLATMEVSVTDGVNEIKAMMQLSV 884 L + VP+L T+ V TDG+ +A++++ V Sbjct: 2097 LDDVKVPRLFTLMVEATDGLFRTEAVVKIKV 2127 Score = 301 bits (739), Expect = 2e-79 Identities = 272/918 (29%), Positives = 417/918 (45%), Gaps = 82/918 (8%) Query: 17 NDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAX 76 N H PVF + E T V ATD+D G N V Y+I V D Sbjct: 680 NRHHPVFRSHDQNIHISESTPIATVVSQFMATDEDKGYNGLVLYSI--VEGD-------- 729 Query: 77 XXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATI 136 V VF I+ +G L LDRE ++ YT+ + A D R S+ + Sbjct: 730 ---------VDSVFNINMFTGELTVAMPLDRETISSYTLNISAVDCG---KHRKSAYTIL 777 Query: 137 HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNT 196 +V I D ND P F + Y V++ E+I+V + + A+D D G N I Y I+ + Sbjct: 778 NVKITDVNDCSPVFDKTVYEVTLPENITV--GQTVTHVHASDKDQGTNGFITYQIV-NDF 834 Query: 197 QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS-NTTQLLINIRDVNDNAP 255 +F ++ +SG VS+ LDYE+ Y++ I+A D ++ +T +++ + D+NDN+P Sbjct: 835 GGKFRVNRISGVVSVGDYLDYEEQEMYKIEIQAMDSSVDNQKVGSTHVIVTLLDINDNSP 894 Query: 256 RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315 F +V E++ + + + A D D G E+ +++ + N ID +S Sbjct: 895 IVKPKKFNVTVQEDLLVNAVVTSIHASDPDSGPGGEIEFSLPESTRKFN------IDSKS 948 Query: 316 GWVYTSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXXXXFMPGQ-YE 372 G + +LD E ++ Y L V TD G P F G+ E Sbjct: 949 GVIRLRQRLDFEQKSTYNLTVRVTDKGSPALFTDVEVVVNVLDVNENSLAPVFSGGRILE 1008 Query: 373 VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432 + E+ P GT V++ ATD D L Y I G +F I G I A LD + Sbjct: 1009 TSINENSPVGTVVISPKATDQD-SWYLKYAIIDGTGVDKFIIDPDT--GAIRTAGELDHE 1065 Query: 433 QERRYVLTVSATD--SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 Y LTV A D S V INI D N+ AP F + Y + E+ P G++V+ Sbjct: 1066 VADHYWLTVQAKDGESYPLYTNIPVLINIVDLNDEAPYFAPSTYYPVLAENLPSGSSVVQ 1125 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550 V+A D D G + + Y+++ NE FVI+PQ+G ITT + LDRE S Y LT Sbjct: 1126 VTAKDPDSG-GSLLRYTITK--GNE-----QNNFVIDPQSGLITTLRPLDREFKSEYKLT 1177 Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS--VSQVGATDA 608 V+A DGG P +S + + D NDN+P FK++ Y + S + QV ATD Sbjct: 1178 VSASDGGTPPVSTDVTFTVKITDENDNQPEFKEKQYVVGVFARQATSKSFGLYQVVATDE 1237 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL-DRESVATHDLKAVAIDGGTPPQ 667 D+G N + Y + K + F+ID SG I TN +L D ES +DL VA D G P Sbjct: 1238 DIGSNADLRYSI-TKGNRDNKFIIDSRSGEIFTNVSLVDGES---YDLTIVAEDNGLPKL 1293 Query: 668 SSTVIVHIKIEDIN---DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 S++ V I + N + PVF + + I E+ I + + I A DPD + Y Sbjct: 1294 STSTNVLIDVIQGNKPSKNAPVFWNKQYSADIQEDKRINSFVLIIGAEDPDFDQ---ITY 1350 Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILV 784 +I G+ N F+++ G + LD E + Y L + A V V I + Sbjct: 1351 NIASGNHGNKFTIDRYGGF----ITVAHSLDREE-KSFYSLRVEATDGYNTASVPVTINI 1405 Query: 785 TDVNDNA--PVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILL 842 DVNDN+ P ++++ D + + P DA V +++Y I+ A Sbjct: 1406 LDVNDNSPQPARREYRAHVAENSDVGTLVTTVKDP--DAGVNGEVEYCIVQTAKAE---- 1459 Query: 843 NETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLND 902 S +L ++ ++ ++ T++ + + E ++ S R I + L S+ V ++D Sbjct: 1460 -----SASLF-KIESHSGRILTVKPLDYETMQEHVLTIKASDRGIPKRETLFSVVVSVDD 1513 Query: 903 MT--AEQFLSPLLGFFID 918 + +FLSPL +D Sbjct: 1514 VNDHKPEFLSPLFESEVD 1531 Score = 289 bits (710), Expect = 6e-76 Identities = 238/865 (27%), Positives = 401/865 (46%), Gaps = 62/865 (7%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 D NDHSP+F Y+ S E GT V + ATD D G A + Y+I+ V A Sbjct: 2436 DTNDHSPIFSEDVYKVSFNENYPEGTFVTMVSATDLDSGNYAHLTYSIDSVDA------- 2488 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR--YTVLVKATDQASPVSDRLSS 132 FRID SG L +R DRE ++ +V ++ATD Sbjct: 2489 ------------MRKFRIDADSGMLYSRLMFDRENSSQAIMSVPIRATDGGGRF-----G 2531 Query: 133 TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192 + V++ID+NDN P F K Y ++ SVT + A+D D +N+A+ Y I+ Sbjct: 2532 FCVVEVHLIDENDNQPIFELKNYDTTISR--SVTMGTPVLMTSASDPDASSNAALTYVIV 2589 Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252 G T F+I++ +G + + + +V+SY + +DGG+P + + I + + + Sbjct: 2590 GHQTPPVFTINAATGVIQVSRE---PEVKSYNFFVLVKDGGNPLLRSIASVKITVLERDA 2646 Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312 F S + +V EN +G + + G ++ Y + K N D +D Sbjct: 2647 RILHFGKSKYDVTVGENAEMGQIVTGLNLV-VPGGNPVDVDYRII-KGNNDNNDRKFGVD 2704 Query: 313 PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE 372 +G V G+LD E + +Y ++V A + A F+ Y Sbjct: 2705 -STGRVRVIGRLDYEIRNRYVMIVEANVSA-INQIARTVVVVQVLDINDVTPKFVSDPYL 2762 Query: 373 VELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 + E+ G+ V+ + A D D + + Y + + + G IT LD Sbjct: 2763 ASIPENIDIGSKVLRVFAEDLDSGSNGMVTYALVSKDKLVKEKFDIDQHTGWITTRGALD 2822 Query: 431 FKQERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYAPVFENAPYTASVFEDAPIGTTV 488 +++ + V ATD+G T++ + + D N+ P F + + ASV EDA IG +V Sbjct: 2823 REKQPSFEFQVRATDNGTTRLTSLTTVRAIVLDVNDTPPKFSQSEFMASVKEDALIGQSV 2882 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 ++ATD D +N ++ Y + +S + A +F I +TG I + LDRE++ Y Sbjct: 2883 TTITATDED--LNTELYYFI---LSGDPQA----RFGIERKTGVIFVHGSLDRESVGSYD 2933 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 L ++A DG S + ++I + D NDN P+ Q +Y +I E+ +G++V VGATDA Sbjct: 2934 LNISASDGLFTSFA---QMKIDIEDANDNPPICTQSIYVEHIKENTPLGSTVLTVGATDA 2990 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 DVG+N + Y + + G+F +D +G + LDRE+ ++ A D G Sbjct: 2991 DVGVNAELTYSV--FGQGFGTFAVD-KNGKMTNLVELDRETRPFYNFMVSAADIGGQACY 3047 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 S + +H ++D+ND+ P+F + E++P+ + +++A D D G N + YS+ Sbjct: 3048 SNISIH--LDDVNDNRPLFSQSSYFTAVYEDAPLKKVLLQVKADDADVGVNRKLTYSLV- 3104 Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVN 788 D +F++ET G E +L E+ E V+ +PPL + V+I V ++N Sbjct: 3105 TDAGGTFTIETGTGIISLEKPLNRELK-ENYTLNVE-VMDGGTPPLSSIATVQIKVLNIN 3162 Query: 789 DNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVT-DKLQYRILSGNNANLILLNETT 846 D P I N + P+G RV A + + D + Y IL G ++ L ++ Sbjct: 3163 DVPPEF-SHSIYHGNVSEDAPIGNEVVRVRAVSRESSNDVITYAILRGADSGLFSIDRKN 3221 Query: 847 GSMTLSPQLNTNVPKLATMEVSVTD 871 G++ ++ +L+ KL T+ V +D Sbjct: 3222 GTIHVNRKLDYETTKLYTLTVEASD 3246 Score = 286 bits (702), Expect = 5e-75 Identities = 263/895 (29%), Positives = 430/895 (48%), Gaps = 89/895 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 IN++D ND +P F Y + E SG++V+ + A D D G + + YTI T Sbjct: 1092 INIVDLNDEAPYFAPSTYYPVLAENLPSGSSVVQVTAKDPDSGGSL-LRYTI------TK 1144 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 E Q+ F ID +SG + T LDRE + Y + V A+D +P + Sbjct: 1145 GNE-------------QNNFVIDPQSGLITTLRPLDREFKSEYKLTVSASDGGTPP---V 1188 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+ T V I D+NDN P+F EK Y V V + + + + ++ ATD D+G+N+ +RY+ Sbjct: 1189 STDVTFTVKITDENDNQPEFKEKQYVVGVFARQATSKSFGLYQVVATDEDIGSNADLRYS 1248 Query: 191 IIGGNTQMQFSIDSLSGDV-SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I GN +F IDS SG++ + V +D E SY L I A+D G P S +T +LI++ Sbjct: 1249 ITKGNRDNKFIIDSRSGEIFTNVSLVDGE---SYDLTIVAEDNGLPKLSTSTNVLIDVIQ 1305 Query: 250 VN---DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 N NAP F+ + + E+ I ++ + A D D ++TY + +GN Sbjct: 1306 GNKPSKNAPVFWNKQYSADIQEDKRINSFVLIIGAEDPDFD---QITYNIA----SGNHG 1358 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 TID G++ + LDRE ++ Y L V ATDG + +A+ Sbjct: 1359 NKFTIDRYGGFITVAHSLDREEKSFYSLRVEATDGYN---TASVPVTINILDVNDNSPQP 1415 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHY---EITGGNTRGRFSITSQNGRGLI 423 +Y +AE+ GT V T+ DA + + Y + + F I S +GR ++ Sbjct: 1416 ARREYRAHVAENSDVGTLVTTVKDPDAGVNGEVEYCIVQTAKAESASLFKIESHSGR-IL 1474 Query: 424 TVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 TV +PLD++ + +VLT+ A+D G R V +++ D N++ P F + + + V Sbjct: 1475 TV-KPLDYETMQEHVLTIKASDRGIPKRETLFSVVVSVDDVNDHKPEFLSPLFESEVDVS 1533 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 A GT +L V ATD D G N+++ YS+ S +N++++ DQ + G ++T Sbjct: 1534 AKAGTAILRVIATDKDDGTNSKLKYSIVSGNTNKSLS-VDQNSGVVKVAGRLST------ 1586 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 + Y L V + DGG P L DV++ V + N F++ Y ++ E++ ++ Sbjct: 1587 -LVHQYALKVQSTDGGEPPLKTQVDVKVKVRGIVKNF-AFEKPKYEVSLPENSPPDQAI- 1643 Query: 602 QVGATDADVGLNGRIH-YELDP-KDREEGSFVIDPASGVIRTNKALDRESVATH---DLK 656 A V NG + YE+ P + F + SGVI + K+ D E V TH +++ Sbjct: 1644 ------ATVVYNGILPVYEIVPGRSPCWRDFTVQRQSGVIISKKSFDAEEV-THCKLEIR 1696 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR------ 710 A + DG Q S+ +V + I+D ND+ P+FE +T +++E SP GT + + + Sbjct: 1697 ANSTDG----QHSSTLVIVTIQDKNDNQPIFEHARITGHVTEGSPQGTAVLDHKGSQLVA 1752 Query: 711 -AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPRKKYEL-VI 767 A D D + + Y I + FS+ G+ + T LDYE +P+ +++ V Sbjct: 1753 VATDQDISGDKLT-YEIVETSARDVFSIHPATGA----ITTAKVLDYEVTPQYAFKIKVT 1807 Query: 768 RAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKL 827 + +P L V+I VTD+ND APV Y + V A D D L Sbjct: 1808 DSGNPRLSAFADVKIHVTDINDIAPVFSASTYHATVYLPSYAGTRVTMVTATDGDSAANL 1867 Query: 828 QYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQL 882 + L+ + L +N TG +T+S T++++V+DG + A +++ Sbjct: 1868 TFS-LARQDTELFAVNPLTGVVTVSNAALLR-RDTYTIKLTVSDGNHTAHARVRI 1920 Score = 283 bits (693), Expect = 6e-74 Identities = 240/818 (29%), Positives = 381/818 (46%), Gaps = 62/818 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND+ P+FE + V EG+ GT VL K G T + ++ D L Sbjct: 1711 VTIQDKNDNQPIFEHARITGHVTEGSPQGTAVLDHK------GSQLVAVATDQDISGDKL 1764 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 E +DVF I +GA+ T LD E +Y +K TD +P RL Sbjct: 1765 TYE-------IVETSARDVFSIHPATGAITTAKVLDYEVTPQYAFKIKVTDSGNP---RL 1814 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+ A + +++ D ND P FS TY +V + + + ATD D AN + ++ Sbjct: 1815 SAFADVKIHVTDINDIAPVFSASTYHATVY--LPSYAGTRVTMVTATDGDSAAN--LTFS 1870 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + +T++ F+++ L+G V+ V + +Y + + DG + + ++ I ++ Sbjct: 1871 LARQDTEL-FAVNPLTGVVT-VSNAALLRRDTYTIKLTVSDGNHTAHA---RVRIRCENL 1925 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 + +F + SV E V + +V V+A G + +TYT+ + ++ +P T Sbjct: 1926 PSSDLQFSRKNYSASVREGVSVDSELVTVRALGYPIG--STITYTIINPSELFHI-VPST 1982 Query: 311 --IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 + R+G+ LDRE+ YQ++V A D PP A A F+ Sbjct: 1983 GVMSIRAGF-----DLDRESIDAYQVIVQARDDSVPPNVAQAAVHVQVIDRNDNQPVFIN 2037 Query: 369 GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 Y + L GT + ATDAD + L Y++ GG+ G FSI+ + G + V Sbjct: 2038 SPYFIVLQLGVAQGTIIGQAQATDADIGSNANLRYDLIGGDP-GYFSISRKTGE--VVVR 2094 Query: 427 QPLD-FKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 + LD K R + L V ATD R++ A+V+I + D PVF+ ++ + ED PIG Sbjct: 2095 RTLDDVKVPRLFTLMVEATDGLFRTE-AVVKIKVVDKET--PVFDQLSFSKVLAEDTPIG 2151 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 + V V+A + A I YS++ + V QF I+ +TG +T LD ET + Sbjct: 2152 SEVTSVTARSPN---GAGILYSITG---GDPV----NQFSIDFKTGVVTLVSSLDYETRT 2201 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 Y L V A D S SD V+++V DVND P F + LY A I E V T+V V A Sbjct: 2202 KYKLVVRATDARTSSHSDVA-VDVTVTDVNDVAPAFNRSLYLATISESTPVDTAVVTVKA 2260 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 D D G+N I+Y + R F ID SGV+ K+LD ES H++ VA D G P Sbjct: 2261 IDGDSGINKEINYFIQNVSRVGAFFKIDKKSGVVFVAKSLDYESRVVHEMIIVAADEGKP 2320 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 + V + + D ND+ P F+ I ++ G + I A DPDEG + YS Sbjct: 2321 SLTGETRVRVVLMDANDNAPRFDKSMYAASILGSASPGQFVTRILATDPDEGDAKKLRYS 2380 Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVT 785 I GG F ++++ G ++T+ + K Y L + + + +V +++ Sbjct: 2381 ITGGQGRQHFQIDSQSG-----VITLSRVVGIKQGKVYGLDVEVSDSVHVSTSKVRVIIG 2435 Query: 786 DVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDAD 822 D ND++P+ + + ++ + +P G F V A D D Sbjct: 2436 DTNDHSPIFSE-DVYKVSFNENYPEGTFVTMVSATDLD 2472 Score = 261 bits (639), Expect = 2e-67 Identities = 264/930 (28%), Positives = 415/930 (44%), Gaps = 86/930 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I+V D ND +PVF Y A+V + +GT V + ATD D N T L DT Sbjct: 1821 KIHVTDINDIAPVFSASTYHATVYLPSYAGTRVTMVTATDGDSAAN----LTFSLARQDT 1876 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLVKATDQASPVSD 128 ++F ++ +G + ++ A+L R R T +K T VSD Sbjct: 1877 ------------------ELFAVNPLTGVVTVSNAALLR----RDTYTIKLT-----VSD 1909 Query: 129 RLSSTATIHVNIIDDN--DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 + TA V I +N + QFS K Y+ SV E +SV D+ ++ ++A +G S Sbjct: 1910 G-NHTAHARVRIRCENLPSSDLQFSRKNYSASVREGVSV-DSELVT-VRALGYPIG--ST 1964 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVK--TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 I Y II N F I +G +S+ LD E + +Y+++++A+D P + Sbjct: 1965 ITYTII--NPSELFHIVPSTGVMSIRAGFDLDRESIDAYQVIVQARDDSVPPNVAQAAVH 2022 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + + D NDN P F S + + V G I + QA DAD G NA L Y D G Sbjct: 2023 VQVIDRNDNQPVFINSPYFIVLQLGVAQGTIIGQAQATDADIGSNANLRY-----DLIGG 2077 Query: 305 VDLPITIDPRSGWVYTSGQLDR-ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 +I ++G V LD + + L+V ATDG Sbjct: 2078 DPGYFSISRKTGEVVVRRTLDDVKVPRLFTLMVEATDG-----LFRTEAVVKIKVVDKET 2132 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423 F + LAED P G+ V ++TA + L Y ITGG+ +FSI + G++ Sbjct: 2133 PVFDQLSFSKVLAEDTPIGSEVTSVTARSPNGAGIL-YSITGGDPVNQFSIDFKT--GVV 2189 Query: 424 TVAQPLDFKQERRYVLTVSATD--SGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 T+ LD++ +Y L V ATD + SD A V + +TD N+ AP F + Y A++ E Sbjct: 2190 TLVSSLDYETRTKYKLVVRATDARTSSHSDVA-VDVTVTDVNDVAPAFNRSLYLATISES 2248 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 P+ T V+ V A D D GIN +I Y + + V+ F I+ ++G + K LD Sbjct: 2249 TPVDTAVVTVKAIDGDSGINKEINYFIQN------VSRVGAFFKIDKKSGVVFVAKSLDY 2302 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 E+ + + + A D G PSL+ T V + ++D NDN P F + +Y A+I+ A G V+ Sbjct: 2303 ESRVVHEMIIVAADEGKPSLTGETRVRVVLMDANDNAPRFDKSMYAASILGSASPGQFVT 2362 Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 ++ ATD D G ++ Y + + F ID SGVI ++ + + + L D Sbjct: 2363 RILATDPDEGDAKKLRYSITGGQGRQ-HFQIDSQSGVITLSRVVGIKQGKVYGLDVEVSD 2421 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 ST V + I D ND P+F D +EN P GT + + A D D G A Sbjct: 2422 S---VHVSTSKVRVIIGDTNDHSPIFSEDVYKVSFNENYPEGTFVTMVSATDLDSGNYAH 2478 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRV 780 + YSI D F ++ G + L M D + S + + IRA + V Sbjct: 2479 LTYSIDSVDAMRKFRIDADSGMLYSRL--MFDRE-NSSQAIMSVPIRATDGGGRFGFCVV 2535 Query: 781 EILVTDVNDNAPV--MKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNN 836 E+ + D NDN P+ +K++ + + P A D D + L Y I+ Sbjct: 2536 EVHLIDENDNQPIFELKNYDTTIS--RSVTMGTPVLMTSASDPDASSNAALTYVIVGHQT 2593 Query: 837 ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE-IKAMMQLSVRLITEEMLLNS 895 + +N TG + +S + K V V DG N ++++ + + ++ + + Sbjct: 2594 PPVFTINAATGVIQVSREPEV---KSYNFFVLVKDGGNPLLRSIASVKITVLERDARILH 2650 Query: 896 ITVRLNDMTAEQFLSPLLGFFIDGLAAIIP 925 D+T + + +G + GL ++P Sbjct: 2651 FGKSKYDVTVGE--NAEMGQIVTGLNLVVP 2678 Score = 260 bits (637), Expect = 4e-67 Identities = 223/833 (26%), Positives = 360/833 (43%), Gaps = 43/833 (5%) Query: 63 ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122 E+ + +P A + F ID ++G + +SLD E +Y ++V+ATD Sbjct: 2153 EVTSVTARSPNGAGILYSITGGDPVNQFSIDFKTGVVTLVSSLDYETRTKYKLVVRATDA 2212 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 + S + V + D ND P F+ Y ++ E V D V+ +KA D D G Sbjct: 2213 RTSSH----SDVAVDVTVTDVNDVAPAFNRSLYLATISESTPV-DTAVVT-VKAIDGDSG 2266 Query: 183 ANSAIRYAIIG-GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 N I Y I F ID SG V + K+LDYE + ++I A D G PS + T Sbjct: 2267 INKEINYFIQNVSRVGAFFKIDKKSGVVFVAKSLDYESRVVHEMIIVAADEGKPSLTGET 2326 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 ++ + + D NDNAPRF S++ S+ + G + R+ A D DEG +L Y++T Sbjct: 2327 RVRVVLMDANDNAPRFDKSMYAASILGSASPGQFVTRILATDPDEGDAKKLRYSITG--- 2383 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 G ID +SG + S + + Y L V +D +T+ Sbjct: 2384 -GQGRQHFQIDSQSGVITLSRVVGIKQGKVYGLDVEVSDS---VHVSTSKVRVIIGDTND 2439 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNG 419 F Y+V E+ P GT V ++ATD D N H Y I + +F I + +G Sbjct: 2440 HSPIFSEDVYKVSFNENYPEGTFVTMVSATDLDSGNYAHLTYSIDSVDAMRKFRIDADSG 2499 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479 + + + + + ATD GGR +V++++ D N+ P+FE Y ++ Sbjct: 2500 MLYSRLMFDRENSSQAIMSVPIRATDGGGRFGFCVVEVHLIDENDNQPIFELKNYDTTIS 2559 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ-FVINPQTGAITTNKL 538 +GT VL+ SA+D D NA +TY + V H F IN TG I ++ Sbjct: 2560 RSVTMGTPVLMTSASDPDASSNAALTYVI--------VGHQTPPVFTINAATGVIQVSR- 2610 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 + Y V +DGG P L V+I+V++ + F + Y + E+A +G Sbjct: 2611 --EPEVKSYNFFVLVKDGGNPLLRSIASVKITVLERDARILHFGKSKYDVTVGENAEMGQ 2668 Query: 599 SVSQVGATDADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 V+ + G + Y + D + F +D ++G +R LD E + + Sbjct: 2669 IVTGLNLV-VPGGNPVDVDYRIIKGNNDNNDRKFGVD-STGRVRVIGRLDYE-IRNRYVM 2725 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 V + Q + +V +++ DIND P F SD I EN IG+ + + A D D Sbjct: 2726 IVEANVSAINQIARTVVVVQVLDINDVTPKFVSDPYLASIPENIDIGSKVLRVFAEDLDS 2785 Query: 717 GPNAVVHYSIKGGDD--SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---AS 771 G N +V Y++ D F ++ G + T LD E + +E +RA + Sbjct: 2786 GSNGMVTYALVSKDKLVKEKFDIDQHTG----WITTRGALDREK-QPSFEFQVRATDNGT 2840 Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRI 831 L + V +V DVND P + + + +D + A D D+ +L Y I Sbjct: 2841 TRLTSLTTVRAIVLDVNDTPPKFSQSEFMASVKEDALIGQSVTTITATDEDLNTELYYFI 2900 Query: 832 LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884 LSG+ + TG + + L+ + +S +DG+ A M++ + Sbjct: 2901 LSGDPQARFGIERKTGVIFVHGSLDRESVGSYDLNISASDGLFTSFAQMKIDI 2953 Score = 238 bits (583), Expect = 1e-60 Identities = 189/611 (30%), Positives = 297/611 (48%), Gaps = 45/611 (7%) Query: 181 VGANSAIRYAIIGGNTQMQFSIDSLSG------DVSLVKTLDYEQVRSYRLVIRAQDGGS 234 V + + + + II GN Q FS+DS D+ K L+ E V SY L + QD + Sbjct: 23 VYSKNHVDFIIISGNEQGMFSVDSRQVSDFNFMDIKTSKRLNRESVASYELNVVVQDKRT 82 Query: 235 PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294 + T++ I + D NDN P F + +++ E++P+ SI R++A DAD G N + Y Sbjct: 83 KRTLDRTKVNITVDDSNDNRPIFLKKKYLKTIPEDIPMHTSIARIEAVDADVGPNGLIYY 142 Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354 + +K + I+P SG V + +L + ++L V A D PP ++ Sbjct: 143 SFKEKTTS------FAINPISGVVSVAQKLSNSARI-HRLTVVARDRALPPSKPKSSRNC 195 Query: 355 XXXXXXXXXXXFMPG---QYEVELAEDEPPGTPVVTLTATDADEDNR---LHYEITGGNT 408 F P + +++ + G TL D D+ + EIT GN Sbjct: 196 QLIVNVQAVNQFSPEFSVKTQLQNVSEGTSGIVYATLGIIDKDKGSNGDIDRVEITSGNL 255 Query: 409 RGRFSITSQNGRGLITVAQPLDFK-QERRYVLTVSATDSGG--RSDTAMVQINITDANNY 465 G FSI S + V +PLD + Y +T++A D G R+ + ++++N+ D N+ Sbjct: 256 DGAFSIKSSPNDYAVQVIKPLDRELAPFGYNVTLTAYDKGTPVRNGSYVLRVNVLDENDN 315 Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525 P F + Y ++ E API T VL V ATD D G N I Y ++ NE +F Sbjct: 316 NPEFNQSRYITNLSELAPIHTPVLRVLATDKDAGSNGNIMYVITR--GNEL-----GKFE 368 Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS---DTTDVEISVVDVNDNEPVFK 582 IN +TG I T LD E+ + LTV A D GVP S T V ++++D ND++P FK Sbjct: 369 INSKTGQIYTKGDLDYESRQRFDLTVAALD-GVPLQSRKISTVPVVVNILDANDHDPEFK 427 Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642 Y ++ ED GTSV V A D D G NG++ Y L + F I+P +G+IRT Sbjct: 428 APEYRKDLYEDLTPGTSVFTVSAEDLDSGGNGKVRYSL--ANLRPVPFEIEPDTGIIRTT 485 Query: 643 KALDRESVATH--DLKAVAIDGGTPPQSST-VIVHIKIEDINDSPPVFESDCLTFYISEN 699 LDR++ +L+ A D GTP + T +V ++++++ND+ PV + + N Sbjct: 486 TNLDRDTGLPEFINLQVRASDFGTPLRRETETLVKMRVKEMNDNAPVLKQFKCNILVDRN 545 Query: 700 SPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758 +P+G I + A D D + + Y G+ +FSL+ + G EL T L Sbjct: 546 APVGVLITTVTAIDIDISDKDQSLMYKSTFGNTGKAFSLDPKTG----ELRTARSL--RG 599 Query: 759 PRKKYELVIRA 769 ++++ L+I+A Sbjct: 600 LQREFTLIIKA 610 Score = 225 bits (550), Expect = 1e-56 Identities = 195/616 (31%), Positives = 290/616 (47%), Gaps = 50/616 (8%) Query: 87 QDVFRIDGRSGA------LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNI 140 Q +F +D R + + T L+RE VA Y + V D+ + R +++ + Sbjct: 39 QGMFSVDSRQVSDFNFMDIKTSKRLNRESVASYELNVVVQDKRTK---RTLDRTKVNITV 95 Query: 141 IDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQF 200 D NDN P F +K Y ++ EDI + + IA+I+A DADVG N I Y+ T F Sbjct: 96 DDSNDNRPIFLKKKYLKTIPEDIPM--HTSIARIEAVDADVGPNGLIYYSFKEKTT--SF 151 Query: 201 SIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD----GGSPSRSNTTQLLINIRDVNDNAPR 256 +I+ +SG VS+ + L R +RL + A+D P S QL++N++ VN +P Sbjct: 152 AINPISGVVSVAQKLS-NSARIHRLTVVARDRALPPSKPKSSRNCQLIVNVQAVNQFSPE 210 Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD--LPITIDPR 314 F ++VSE G + D D+G N ++ + +GN+D I P Sbjct: 211 FSVKTQLQNVSEGTS-GIVYATLGIIDKDKGSNGDIDRV---EITSGNLDGAFSIKSSPN 266 Query: 315 SGWVYTSGQLDRE-TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373 V LDRE Y + +TA D G P R+ + F +Y Sbjct: 267 DYAVQVIKPLDRELAPFGYNVTLTAYDKGTPVRNGSYVLRVNVLDENDNNPEFNQSRYIT 326 Query: 374 ELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431 L+E P TPV+ + ATD D + + Y IT GN G+F I S+ G+ I LD+ Sbjct: 327 NLSELAPIHTPVLRVLATDKDAGSNGNIMYVITRGNELGKFEINSKTGQ--IYTKGDLDY 384 Query: 432 KQERRYVLTVSATD----SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 + +R+ LTV+A D + T V +NI DAN++ P F+ Y ++ED GT+ Sbjct: 385 ESRQRFDLTVAALDGVPLQSRKISTVPVVVNILDANDHDPEFKAPEYRKDLYEDLTPGTS 444 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET-MSG 546 V VSA D D G N ++ YSL++ F I P TG I T LDR+T + Sbjct: 445 VFTVSAEDLDSGGNGKVRYSLAN--------LRPVPFEIEPDTGIIRTTTNLDRDTGLPE 496 Query: 547 YL-LTVTARDGGVPSLSDT-TDVEISVVDVNDNEPVFKQQLYTANIMED--ALVGTSVSQ 602 ++ L V A D G P +T T V++ V ++NDN PV KQ + NI+ D A VG ++ Sbjct: 497 FINLQVRASDFGTPLRRETETLVKMRVKEMNDNAPVLKQ--FKCNILVDRNAPVGVLITT 554 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 V A D D+ + +F +DP +G +RT ++L R L A DG Sbjct: 555 VTAIDIDISDKDQSLMYKSTFGNTGKAFSLDPKTGELRTARSL-RGLQREFTLIIKATDG 613 Query: 663 -GTPPQSSTVIVHIKI 677 P + VI+ I I Sbjct: 614 IQESPDTHPVILKISI 629 Score = 177 bits (431), Expect = 4e-42 Identities = 174/581 (29%), Positives = 260/581 (44%), Gaps = 44/581 (7%) Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377 + TS +L+RE+ A Y+L V D F+ +Y + E Sbjct: 57 IKTSKRLNRESVASYELNVVVQDKRTKRTLDRTKVNITVDDSNDNRPIFLKKKYLKTIPE 116 Query: 378 DEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435 D P T + + A DAD + ++Y T F+I +G +++VAQ L R Sbjct: 117 DIPMHTSIARIEAVDADVGPNGLIYYSFKEKTTS--FAINPISG--VVSVAQKLS-NSAR 171 Query: 436 RYVLTVSATDSG------GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 + LTV A D S + +N+ N ++P F +V E G Sbjct: 172 IHRLTVVARDRALPPSKPKSSRNCQLIVNVQAVNQFSPEFSVKTQLQNVSEGTS-GIVYA 230 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI--NPQTGAITTNKLLDRETMS-G 546 + D D G N I EI++ + D F I +P A+ K LDRE G Sbjct: 231 TLGIIDKDKGSNGDID---RVEITS---GNLDGAFSIKSSPNDYAVQVIKPLDRELAPFG 284 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y +T+TA D G P + + + ++V+D NDN P F Q Y N+ E A + T V +V AT Sbjct: 285 YNVTLTAYDKGTPVRNGSYVLRVNVLDENDNNPEFNQSRYITNLSELAPIHTPVLRVLAT 344 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D D G NG I Y + + E G F I+ +G I T LD ES DL A+DG P Sbjct: 345 DKDAGSNGNIMYVIT-RGNELGKFEINSKTGQIYTKGDLDYESRQRFDLTVAALDG-VPL 402 Query: 667 QS---STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 QS STV V + I D ND P F++ + E+ GT++ + A D D G N V Sbjct: 403 QSRKISTVPVVVNILDANDHDPEFKAPEYRKDLYEDLTPGTSVFTVSAEDLDSGGNGKVR 462 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY-ELVIRAAS--PPLWNDVR- 779 YS+ +N + D + T +LD ++ ++ L +RA+ PL + Sbjct: 463 YSL-----ANLRPVPFEIEPDTGIIRTTTNLDRDTGLPEFINLQVRASDFGTPLRRETET 517 Query: 780 -VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADVTDK---LQYRILSG 834 V++ V ++NDNAPV+K F+ ++ PVG V A D D++DK L Y+ G Sbjct: 518 LVKMRVKEMNDNAPVLKQFKCNILVDRNA-PVGVLITTVTAIDIDISDKDQSLMYKSTFG 576 Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE 875 N L+ TG + + L + + T+ + TDG+ E Sbjct: 577 NTGKAFSLDPKTGELRTARSLR-GLQREFTLIIKATDGIQE 616 Score = 176 bits (428), Expect = 8e-42 Identities = 167/576 (28%), Positives = 250/576 (43%), Gaps = 52/576 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+ P+F ++Y ++ E T++ ++A D D+G N + Y+ + T Sbjct: 93 ITVDDSNDNRPIFLKKKYLKTIPEDIPMHTSIARIEAVDADVGPNGLIYYSFKEKTTS-- 150 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDRE-KVARYTVLVKATDQASPVSDR 129 F I+ SG + L ++ R TV+ A D+A P S Sbjct: 151 -------------------FAINPISGVVSVAQKLSNSARIHRLTVV--ARDRALPPSKP 189 Query: 130 LSS-TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI- 187 SS + VN+ N P+FS KT +V E T V A + D D G+N I Sbjct: 190 KSSRNCQLIVNVQAVNQFSPEFSVKTQLQNVSEG---TSGIVYATLGIIDKDKGSNGDID 246 Query: 188 RYAIIGGNTQMQFSIDSLSGD--VSLVKTLDYEQVR-SYRLVIRAQDGGSPSRSNTTQLL 244 R I GN FSI S D V ++K LD E Y + + A D G+P R+ + L Sbjct: 247 RVEITSGNLDGAFSIKSSPNDYAVQVIKPLDRELAPFGYNVTLTAYDKGTPVRNGSYVLR 306 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 +N+ D NDN P F S + ++SE PI ++RV A D D G N + Y +T + G Sbjct: 307 VNVLDENDNNPEFNQSRYITNLSELAPIHTPVLRVLATDKDAGSNGNIMYVITRGNELGK 366 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG--DPPRSATATXXXXXXXXXXX 362 + I+ ++G +YT G LD E++ ++ L V A DG + +T Sbjct: 367 FE----INSKTGQIYTKGDLDYESRQRFDLTVAALDGVPLQSRKISTVPVVVNILDANDH 422 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG-RFSITSQNGRG 421 F +Y +L ED PGT V T++A D D + N R F I G Sbjct: 423 DPEFKAPEYRKDLYEDLTPGTSVFTVSAEDLDSGGNGKVRYSLANLRPVPFEIEPDTGII 482 Query: 422 LITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASV 478 T D L V A+D G R +V++ + + N+ APV + V Sbjct: 483 RTTTNLDRDTGLPEFINLQVRASDFGTPLRRETETLVKMRVKEMNDNAPVLKQFKCNILV 542 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 +AP+G + V+A D D+ Q + S N A F ++P+TG + T + Sbjct: 543 DRNAPVGVLITTVTAIDIDISDKDQ-SLMYKSTFGNTGKA-----FSLDPKTGELRTARS 596 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDV--EISVV 572 L R + L + A D G+ DT V +IS+V Sbjct: 597 L-RGLQREFTLIIKATD-GIQESPDTHPVILKISIV 630 Score = 161 bits (392), Expect = 2e-37 Identities = 162/600 (27%), Positives = 269/600 (44%), Gaps = 57/600 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NV N SP F ++ +V EG +SG TL D+D G N +++ +E+ + Sbjct: 199 VNVQAVNQFSPEFSVKTQLQNVSEG-TSGIVYATLGIIDKDKGSNGDID-RVEITSG--- 253 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA-RYTVLVKATDQASPVSDR 129 N + A V + LDRE Y V + A D+ +PV + Sbjct: 254 NLDGAFSIKSSPNDYAVQVIK------------PLDRELAPFGYNVTLTAYDKGTPVRN- 300 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + + VN++D+NDN P+F++ Y ++ E ++ PV+ ++ ATD D G+N I Y Sbjct: 301 --GSYVLRVNVLDENDNNPEFNQSRYITNLSE-LAPIHTPVL-RVLATDKDAGSNGNIMY 356 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG--SPSRSNTTQLLINI 247 I GN +F I+S +G + LDYE + + L + A DG + +T +++NI Sbjct: 357 VITRGNELGKFEINSKTGQIYTKGDLDYESRQRFDLTVAALDGVPLQSRKISTVPVVVNI 416 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 D ND+ P F +++ + E++ G S+ V A D D G N ++ Y++ + + Sbjct: 417 LDANDHDPEFKAPEYRKDLYEDLTPGTSVFTVSAEDLDSGGNGKVRYSLANLR-----PV 471 Query: 308 PITIDPRSGWVYTSGQLDRETQAK--YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 P I+P +G + T+ LDR+T L V A+D G P R T T Sbjct: 472 PFEIEPDTGIIRTTTNLDRDTGLPEFINLQVRASDFGTPLRRETETLVKMRVKEMNDNAP 531 Query: 366 FMPGQYEVELAEDE--PPGTPVVTLTATD---ADEDNRLHYEITGGNTRGRFSITSQNGR 420 + Q++ + D P G + T+TA D +D+D L Y+ T GNT FS+ + G Sbjct: 532 VLK-QFKCNILVDRNAPVGVLITTVTAIDIDISDKDQSLMYKSTFGNTGKAFSLDPKTGE 590 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRS-DTAMVQINIT-DANNYAPVFENAPYTASV 478 + A+ L Q R + L + ATD S DT V + I+ A +N T V Sbjct: 591 --LRTARSLRGLQ-REFTLIIKATDGIQESPDTHPVILKISIVGGRQARKLQNHVSTKCV 647 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE---AVAHHDQQFVINPQTG-AIT 534 D+P+ L + + ++ ++++ N HDQ I+ T A Sbjct: 648 --DSPLYAKALKIKQEQKSYSSLQPLIFA-TAKLHNRHHPVFRSHDQNIHISESTPIATV 704 Query: 535 TNKLLDRETMSGY--LLTVTARDGGVPSLSDTT--DVEISVVDVNDNEPVFKQQLYTANI 590 ++ + + GY L+ + +G V S+ + E++V D E + YT NI Sbjct: 705 VSQFMATDEDKGYNGLVLYSIVEGDVDSVFNINMFTGELTVAMPLDRETI---SSYTLNI 761 Score = 160 bits (389), Expect = 4e-37 Identities = 144/543 (26%), Positives = 240/543 (44%), Gaps = 39/543 (7%) Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL----ITVA 426 Y + E P GTPV N + + I GN +G FS+ S+ I + Sbjct: 1 YSAFIPEITPIGTPVKCDLKMGVYSKNHVDFIIISGNEQGMFSVDSRQVSDFNFMDIKTS 60 Query: 427 QPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 + L+ + Y L V D + D V I + D+N+ P+F Y ++ ED P+ Sbjct: 61 KRLNRESVASYELNVVVQDKRTKRTLDRTKVNITVDDSNDNRPIFLKKKYLKTIPEDIPM 120 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 T++ + A D+DVG N I YS + ++ F INP +G ++ + L Sbjct: 121 HTSIARIEAVDADVGPNGLIYYSFKEKTTS---------FAINPISGVVSVAQKLSNSAR 171 Query: 545 SGYLLTVTARDGGV----PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 + LTV ARD + P S + ++V VN P F + N+ E G Sbjct: 172 I-HRLTVVARDRALPPSKPKSSRNCQLIVNVQAVNQFSPEFSVKTQLQNVSE-GTSGIVY 229 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVI--DPASGVIRTNKALDRE-SVATHDLKA 657 + +G D D G NG I +G+F I P ++ K LDRE + +++ Sbjct: 230 ATLGIIDKDKGSNGDIDRVEITSGNLDGAFSIKSSPNDYAVQVIKPLDRELAPFGYNVTL 289 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A D GTP ++ + ++ + + D ND+ P F +SE +PI T + + A D D G Sbjct: 290 TAYDKGTPVRNGSYVLRVNVLDENDNNPEFNQSRYITNLSELAPIHTPVLRVLATDKDAG 349 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLW- 775 N + Y I G++ F + ++ G ++ T DLDYES R++++L + A PL Sbjct: 350 SNGNIMYVITRGNELGKFEINSKTG----QIYTKGDLDYES-RQRFDLTVAALDGVPLQS 404 Query: 776 ---NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYR 830 + V V + + D ND+ P K + + Y+D P V A D D K++Y Sbjct: 405 RKISTVPVVVNILDANDHDPEFKAPEYRKDLYEDLTPGTSVFTVSAEDLDSGGNGKVRYS 464 Query: 831 ILSGNNANLILLNETTGSMTLSPQL--NTNVPKLATMEVSVTDGVNEIKAMMQLSVRLIT 888 L+ + TG + + L +T +P+ ++V +D ++ + V++ Sbjct: 465 -LANLRPVPFEIEPDTGIIRTTTNLDRDTGLPEFINLQVRASDFGTPLRRETETLVKMRV 523 Query: 889 EEM 891 +EM Sbjct: 524 KEM 526 Score = 134 bits (325), Expect = 3e-29 Identities = 100/335 (29%), Positives = 158/335 (47%), Gaps = 30/335 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++NVLD ND++P F +Y ++ E A T VL + ATD+D G N + Y I + Sbjct: 306 RVNVLDENDNNPEFNQSRYITNLSELAPIHTPVLRVLATDKDAGSNGNIMYVI--TRGNE 363 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L F I+ ++G + T+ LD E R+ + V A D P+ R Sbjct: 364 LGK-----------------FEINSKTGQIYTKGDLDYESRQRFDLTVAALD-GVPLQSR 405 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 ST + VNI+D ND+ P+F Y + ED+ T + + A D D G N +RY Sbjct: 406 KISTVPVVVNILDANDHDPEFKAPEYRKDLYEDL--TPGTSVFTVSAEDLDSGGNGKVRY 463 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQ--VRSYRLVIRAQDGGSPSRSNTTQLL-IN 246 + + + F I+ +G + LD + L +RA D G+P R T L+ + Sbjct: 464 S-LANLRPVPFEIEPDTGIIRTTTNLDRDTGLPEFINLQVRASDFGTPLRRETETLVKMR 522 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 ++++NDNAP V N P+G I V A D D ++ ++ K GN Sbjct: 523 VKEMNDNAPVLKQFKCNILVDRNAPVGVLITTVTAIDID---ISDKDQSLMYKSTFGNTG 579 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341 ++DP++G + T+ L R Q ++ L++ ATDG Sbjct: 580 KAFSLDPKTGELRTARSL-RGLQREFTLIIKATDG 613 Score = 97.5 bits (232), Expect = 5e-18 Identities = 77/277 (27%), Positives = 131/277 (47%), Gaps = 28/277 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I+V D ND+ P F ++Y A V E ++ GT VL + ATD+D G NA+++Y+I Sbjct: 3259 RISVTDSNDNGPEFSEKRYSAKVDENSALGTFVLQVFATDRDSGTNAQIKYSI------- 3311 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 DA F+I +G + +DRE+VA Y + V+A DQ P + Sbjct: 3312 AEGNDAKK------------FKIVEETGVIKVSGDIDREEVASYRLKVRAQDQGLP--PQ 3357 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA-IR 188 ++ T + + + D NDN P+FS T + E S N + ++ D D N A + Sbjct: 3358 VADT-VVDIEVTDVNDNSPEFSSTNLTTVLSE--SSLPNAAVIHLRPHDRDALGNGAPYQ 3414 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 + +I G+ +F + S +G ++ + + + YRL + D G P +S + + I Sbjct: 3415 FTLISGDAS-RFKLHS-NGLITKIGDVSHSD-GQYRLRVLVADNGHPPQSTEVSITVKIA 3471 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD 285 + + P + ++ + G I RV+A D D Sbjct: 3472 ESKTHPPNVHPLTVYVNLYGSNLNGGVIGRVKATDKD 3508 >UniRef50_UPI00006A0F37 Cluster: dachsous 2 isoform 1; n=1; Xenopus tropicalis|Rep: dachsous 2 isoform 1 - Xenopus tropicalis Length = 3630 Score = 420 bits (1035), Expect = e-115 Identities = 281/900 (31%), Positives = 456/900 (50%), Gaps = 53/900 (5%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I V D ND++P+F + Y S+ E +T+L + A D+D G N+++ Y + Sbjct: 2110 KIIVSDFNDNAPIFTQEVYTVSLNENIPVNSTILRVSANDKDEGSNSQITYYFAASSKQA 2169 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSD 128 +N F ID SG + T+ +LD EK+ R + + + A D SP Sbjct: 2170 MN-----------------TFIIDSISGEVKTKENLDFEKIEREFQIQIMAKDHGSP--- 2209 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 L+S+ + + I+D NDN P FS++ Y VS++E+I + N I + A D D G NS IR Sbjct: 2210 SLNSSTNLRICIVDFNDNLPVFSQEVYKVSINENIPI--NSTILYVSANDKDEGINSQIR 2267 Query: 189 YAIIGGNTQM--QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 Y + Q+ F I+S+SG + + LD+E+ + Y + ++A D + + T + I Sbjct: 2268 YYFSTSSKQILNTFIINSISGAIMTKENLDFEKTKLYEISVQANDQYT-GETGTALIRIT 2326 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + D NDN P F +++ S++EN+P+ +++ V A D DEG+N++LTY+ + + Sbjct: 2327 VTDANDNFPMFSQEIYKVSINENMPLNSTVLYVSASDKDEGINSQLTYSFSSA--SKQAT 2384 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 I+P+SG + TS LDRE ++ Y + + ATD G PP S+ T F Sbjct: 2385 NAFAINPQSGEIVTSSTLDREMKSHYDITIQATDKGSPPLSSRKTIRLDVSDINDNAPVF 2444 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLIT 424 Y V ++E+ PG + ++ A+D D E+ +L Y N I S ++ Sbjct: 2445 EKSTYIVYISENNEPGASIYSIQASDKDSEENAKLVYSSITSNREENLRIDSDISELVLE 2504 Query: 425 VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 + PL+ + E + + ++A D G ++ TA+++I +TD N+ P+F YT S+ E+ Sbjct: 2505 I--PLNRETESIHEIVLTAFDGGSPMQTGTALIRITVTDMNDNFPIFGQEVYTVSINENI 2562 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 P+ +TVL VSA D D GIN+QITYS S+ S +A + F IN +TG I T + LD E Sbjct: 2563 PLNSTVLCVSANDKDQGINSQITYSFSA-TSKQA----SRSFSINSETGEIKTKENLDFE 2617 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 Y ++V A+DGG +++I+V D NDN PVF Q++Y NI E+ + ++V Q Sbjct: 2618 KTKNYEISVQAKDGGGLVSHAKINIQITVTDFNDNFPVFTQEVYKVNIHENIPIHSTVLQ 2677 Query: 603 VGATDADVGLNGRIHYELDPKDREE-GSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 V A+D D G+N +I Y F I+P SG I T +D E +D+ A D Sbjct: 2678 VNASDKDEGINAQITYSFGTTATNVLRIFAINPKSGEITTKGNVDFEETKYYDISVQAQD 2737 Query: 662 G--GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 G G+P SS + + I DIND+PP FE Y++EN+ G +I I+A D D N Sbjct: 2738 GDKGSPTLSSLKTIRLDILDINDNPPKFEKSNYVAYVTENNQPGASIYSIQAIDEDTEEN 2797 Query: 720 AVVHYSI--KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWN 776 V YSI +N+ + E+ T ++D+E K Y++ + A L + Sbjct: 2798 GKVVYSIFTNNTTSANNVHRIFSINPNNGEITTKGNVDFEEV-KYYDISVEAQDGGSLVS 2856 Query: 777 DVRVEIL-VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILS 833 +V I V+D+NDN P + + ++ P + A D D + K+ Y I + Sbjct: 2857 HSKVLIQNVSDINDNPPKFEKSNYVAYVTENNQPGSSIFSIKAIDKDTEENGKVVYSISN 2916 Query: 834 G----NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889 ++ + I +N TG +T L+ + ++ +DG N ++ L +T+ Sbjct: 2917 NTVEFSSVSYISINPVTGFVTNQTSLDRETQSNHELILTASDGGNPVQTGTTLIKITVTD 2976 Score = 420 bits (1034), Expect = e-115 Identities = 286/881 (32%), Positives = 445/881 (50%), Gaps = 61/881 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I V D ND+ PVF + Y+ S+ E +TVLT+ ATD+D G NA++ Y+ + + Sbjct: 923 RIAVTDSNDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQIMYSFSKTSGNN 982 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L+ +F I+ SG + T+ + + E Y + V A D SP Sbjct: 983 LHTS---------------MFSINYTSGEIKTKQNFNFEAKKFYEISVYAKDYGSP---S 1024 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVT-----DNPVIAKIKATDADVGAN 184 LS A++ + I D NDN P+ + + SVD + +I K+ A DAD G N Sbjct: 1025 LSCNASLTIRITDQNDNVPKILYPS-SESVDSSFEMVPVASEQGALITKVVAVDADSGHN 1083 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 + + Y ++ G+ FSI +G++ ++LD E+V Y + I+A D GSP SN + Sbjct: 1084 AWLSYHVVQGSEPSLFSISQNTGEIRTSRSLDREKVPWYNITIQATDRGSPHLSNIKLIK 1143 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 ++I DVNDNAP F S + ++EN G SI R+QA D D G NA+L+Y + G+ Sbjct: 1144 LDISDVNDNAPVFTKSSYVAYIAENNLAGASIYRIQASDIDAGDNAKLSYHVVQ----GS 1199 Query: 305 VDLPITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 +I +G + TS + LDRETQ+ ++L++TA+DGG+P R+ TA Sbjct: 1200 EPSLFSISQNTGEIRTSQKPLDRETQSIHELILTASDGGNPLRTGTALIRIIVTDSNDNL 1259 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRF-SITSQNG- 419 F Y+V ++E+ P + V+ LTATD DE ++ Y I+ + + S+ + N Sbjct: 1260 PVFTQEVYKVSISENAPINSSVIILTATDKDEGTNAQITYSISKTSENNFYTSVFNINPV 1319 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTAS 477 G IT+ R ++T +A+D G R+ TA++++ +TDAN+ PVF Y S Sbjct: 1320 MGEITIKVSTSSSYYR--IITTTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVS 1377 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 + E+ PI +TVL V+A+D D G NAQITYS S + +N + + Sbjct: 1378 ISENTPINSTVLRVNASDMDEGTNAQITYSFS-------------RTSVNSLHAKLVLER 1424 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LDRE + + L +TA DGG P + T + + V D NDN PVF Q++Y +I E+ + Sbjct: 1425 PLDREIKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISENTPIN 1484 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREE---GSFVIDPASGVIRTNKALDRESVATHD 654 ++V +V A+D D G N +I Y F I+P SG I+T + LDRE+ H+ Sbjct: 1485 STVLRVNASDMDEGTNAQITYSFSRTSENSLHASMFSINPTSGEIKTKRPLDRETKNIHE 1544 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 L A DGGTP ++ T ++ + + D ND+ PVF + ISEN+PI +T+ + A D Sbjct: 1545 LLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISENTPINSTVLRVNASDM 1604 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---S 771 DEG NA + YS ++ + E+ T LD E+ + +EL++ A+ + Sbjct: 1605 DEGTNAQITYSFSRTSVNSLHASMFSINPTSGEITTKKPLDREA-QTSHELILTASDGGN 1663 Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRI 831 P ++I+VTD NDN PV + + + + VG V +A K+ Y I Sbjct: 1664 PVRTGTALIQIIVTDANDNLPVFTEV-LYTVSISENTAVGSV--VLCVNASSNAKITYSI 1720 Query: 832 LSGNNAN-LILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 N + +N TG + + K ME+ D Sbjct: 1721 SETNTMSPYFSINIETGVLYAQQSFDYEQHKQFEMEIMAKD 1761 Score = 410 bits (1009), Expect = e-112 Identities = 286/906 (31%), Positives = 448/906 (49%), Gaps = 73/906 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I V D ND+ PVF Y+AS+ E + TTVL + ATD+D G NA++ Y+ + Sbjct: 820 KITVTDVNDNVPVFTQAVYKASISENSPVNTTVLYVNATDKDEGINAQIVYSFSVS---- 875 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + F ID +SG L + LDRE + +++ A+D +PV Sbjct: 876 -----------------EKYFSIDLQSGMLYVKKPLDRETQTIHELILTASDGGNPVR-- 916 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S TA I + + D NDN P F+++ Y VS+ E+I + N + + ATD D G N+ I Y Sbjct: 917 -SGTALIRIAVTDSNDNLPVFTQEVYKVSISENIPI--NSTVLTVNATDRDEGTNAQIMY 973 Query: 190 AI--IGGNT--QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 + GN FSI+ SG++ + ++E + Y + + A+D GSPS S L I Sbjct: 974 SFSKTSGNNLHTSMFSINYTSGEIKTKQNFNFEAKKFYEISVYAKDYGSPSLSCNASLTI 1033 Query: 246 NIRDVNDNAPR--FYTSLFQESVSENVPI----GYSIVRVQAYDADEGVNAELTYTMTDK 299 I D NDN P+ + +S +S E VP+ G I +V A DAD G NA L+Y + Sbjct: 1034 RITDQNDNVPKILYPSSESVDSSFEMVPVASEQGALITKVVAVDADSGHNAWLSYHVVQ- 1092 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 G+ +I +G + TS LDRE Y + + ATD G P S Sbjct: 1093 ---GSEPSLFSISQNTGEIRTSRSLDREKVPWYNITIQATDRGSPHLSNIKLIKLDISDV 1149 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRGRFSITSQ 417 F Y +AE+ G + + A+D D DN +L Y + G+ FSI SQ Sbjct: 1150 NDNAPVFTKSSYVAYIAENNLAGASIYRIQASDIDAGDNAKLSYHVVQGSEPSLFSI-SQ 1208 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYT 475 N + T +PLD + + + L ++A+D G R+ TA+++I +TD+N+ PVF Y Sbjct: 1209 NTGEIRTSQKPLDRETQSIHELILTASDGGNPLRTGTALIRIIVTDSNDNLPVFTQEVYK 1268 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 S+ E+API ++V++++ATD D G NAQITYS+S N + F INP G IT Sbjct: 1269 VSISENAPINSSVIILTATDKDEGTNAQITYSISKTSENN---FYTSVFNINPVMGEIT- 1324 Query: 536 NKLLDRETMSGY--LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593 + T S Y ++T TA DGG P + T + + V D NDN PVF Q++Y +I E+ Sbjct: 1325 ---IKVSTSSSYYRIITTTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISEN 1381 Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653 + ++V +V A+D D G N +I Y ++ + + LDRE H Sbjct: 1382 TPINSTVLRVNASDMDEGTNAQITYSFSRTS-------VNSLHAKLVLERPLDREIKNIH 1434 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713 +L A DGGTP ++ T ++ + + D ND+ PVF + ISEN+PI +T+ + A D Sbjct: 1435 ELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISENTPINSTVLRVNASD 1494 Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA--- 770 DEG NA + YS +++ + E+ T LD E+ + +EL++ A+ Sbjct: 1495 MDEGTNAQITYSFSRTSENSLHASMFSINPTSGEIKTKRPLDRET-KNIHELLLTASDGG 1553 Query: 771 SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPAYDAD------V 823 +P + ++VTD NDN PV ++ + + P+ RV A D D + Sbjct: 1554 TPVRTGTALIRVIVTDANDNTPVFTQ-EVYKVSISENTPINSTVLRVNASDMDEGTNAQI 1612 Query: 824 TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLS 883 T ++ +A++ +N T+G +T L+ + ++ +DG N ++ L Sbjct: 1613 TYSFSRTSVNSLHASMFSINPTSGEITTKKPLDREAQTSHELILTASDGGNPVRTGTALI 1672 Query: 884 VRLITE 889 ++T+ Sbjct: 1673 QIIVTD 1678 Score = 402 bits (991), Expect = e-110 Identities = 293/973 (30%), Positives = 475/973 (48%), Gaps = 55/973 (5%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++++ D ND+ PVF Y + E G ++ T+ ATD D G NA++ Y+I Sbjct: 1899 KLDISDVNDNPPVFRKSLYTTYLPENNLPGASIYTVHATDVDSGDNAKLIYSIS-----N 1953 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N ED GR ++T +LDRE+ Y + + ATD+ P + Sbjct: 1954 ANTEDFPLISST------------GRFYRIVTTNNLDRERTPFYNITILATDRGYP---Q 1998 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 +S I V I D NDN P F + TY + E+ +I + A D DVG N+ + Y Sbjct: 1999 RTSKKMIGVEISDVNDNAPLFIKPTYDAFLPENN--LPGALIYSLHAKDLDVGDNAKVTY 2056 Query: 190 AIIGGNTQMQFSIDS-LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 +I+ NT FS+ S S ++ LD E + LV+ A DGG+P ++ T + I + Sbjct: 2057 SIL--NTNTDFSVSSYFSINIETGAPLDRETESIHELVLTAFDGGNPVQTGTAIIKIIVS 2114 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D NDNAP F ++ S++EN+P+ +I+RV A D DEG N+++TY + Sbjct: 2115 DFNDNAPIFTQEVYTVSLNENIPVNSTILRVSANDKDEGSNSQITYYFAAS--SKQAMNT 2172 Query: 309 ITIDPRSGWVYTSGQLDRE-TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 ID SG V T LD E + ++Q+ + A D G P +++ F Sbjct: 2173 FIIDSISGEVKTKENLDFEKIEREFQIQIMAKDHGSPSLNSSTNLRICIVDFNDNLPVFS 2232 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITV 425 Y+V + E+ P + ++ ++A D DE ++++ Y + + + + + G I Sbjct: 2233 QEVYKVSINENIPINSTILYVSANDKDEGINSQIRYYFSTSSKQILNTFIINSISGAIMT 2292 Query: 426 AQPLDFKQERRYVLTVSATDS-GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 + LDF++ + Y ++V A D G + TA+++I +TDAN+ P+F Y S+ E+ P+ Sbjct: 2293 KENLDFEKTKLYEISVQANDQYTGETGTALIRITVTDANDNFPMFSQEIYKVSINENMPL 2352 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 +TVL VSA+D D GIN+Q+TYS SS S +A F INPQ+G I T+ LDRE Sbjct: 2353 NSTVLYVSASDKDEGINSQLTYSFSS-ASKQAT----NAFAINPQSGEIVTSSTLDREMK 2407 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 S Y +T+ A D G P LS + + V D+NDN PVF++ Y I E+ G S+ + Sbjct: 2408 SHYDITIQATDKGSPPLSSRKTIRLDVSDINDNAPVFEKSTYIVYISENNEPGASIYSIQ 2467 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 A+D D N ++ Y +REE + ID + L+RE+ + H++ A DGG+ Sbjct: 2468 ASDKDSEENAKLVYSSITSNREE-NLRIDSDISELVLEIPLNRETESIHEIVLTAFDGGS 2526 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 P Q+ T ++ I + D+ND+ P+F + T I+EN P+ +T+ + A+D D+G N+ + Y Sbjct: 2527 PMQTGTALIRITVTDMNDNFPIFGQEVYTVSINENIPLNSTVLCVSANDKDQGINSQITY 2586 Query: 725 SIKGGDD--SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVR 779 S S SFS+ + G E+ T +LD+E K YE+ ++A + Sbjct: 2587 SFSATSKQASRSFSINSETG----EIKTKENLDFEK-TKNYEISVQAKDGGGLVSHAKIN 2641 Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPAYDADVTDKLQYRILSGNNAN 838 ++I VTD NDN PV ++ N + P+ +V A D D Q G A Sbjct: 2642 IQITVTDFNDNFPVFTQ-EVYKVNIHENIPIHSTVLQVNASDKDEGINAQITYSFGTTAT 2700 Query: 839 LIL----LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQL-SVRLITEEMLL 893 +L +N +G +T ++ K + V DG + L ++RL ++ Sbjct: 2701 NVLRIFAINPKSGEITTKGNVDFEETKYYDISVQAQDGDKGSPTLSSLKTIRLDILDIND 2760 Query: 894 NSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKEN-IYIFSVQDDTDVTGNILNVSFS 952 N ++ A + G I + AI +EN ++S+ + + N ++ FS Sbjct: 2761 NPPKFEKSNYVAYVTENNQPGASIYSIQAIDEDTEENGKVVYSIFTNNTTSANNVHRIFS 2820 Query: 953 ARRPDAEVGVAGD 965 + E+ G+ Sbjct: 2821 INPNNGEITTKGN 2833 Score = 395 bits (973), Expect = e-108 Identities = 256/800 (32%), Positives = 409/800 (51%), Gaps = 50/800 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I ++D ND+ PVF + Y+ S+ E +T+L + A D+D G N+++ Y + Sbjct: 2218 RICIVDFNDNLPVFSQEVYKVSINENIPINSTILYVSANDKDEGINSQIRYYFSTSSKQI 2277 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 LN F I+ SGA++T+ +LD EK Y + V+A DQ + + Sbjct: 2278 LN-----------------TFIINSISGAIMTKENLDFEKTKLYEISVQANDQYTGET-- 2318 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 TA I + + D NDN+P FS++ Y VS++E++ + N + + A+D D G NS + Y Sbjct: 2319 --GTALIRITVTDANDNFPMFSQEIYKVSINENMPL--NSTVLYVSASDKDEGINSQLTY 2374 Query: 190 AIIGGNTQM--QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 + + Q F+I+ SG++ TLD E Y + I+A D GSP S+ + +++ Sbjct: 2375 SFSSASKQATNAFAINPQSGEIVTSSTLDREMKSHYDITIQATDKGSPPLSSRKTIRLDV 2434 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 D+NDNAP F S + +SEN G SI +QA D D NA+L Y+ T N + Sbjct: 2435 SDINDNAPVFEKSTYIVYISENNEPGASIYSIQASDKDSEENAKLVYS----SITSNREE 2490 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 + ID + L+RET++ +++++TA DGG P ++ TA F Sbjct: 2491 NLRIDSDISELVLEIPLNRETESIHEIVLTAFDGGSPMQTGTALIRITVTDMNDNFPIFG 2550 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITV 425 Y V + E+ P + V+ ++A D D+ ++++ Y + + + S + + G I Sbjct: 2551 QEVYTVSINENIPLNSTVLCVSANDKDQGINSQITYSFSATSKQASRSFSINSETGEIKT 2610 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAP 483 + LDF++ + Y ++V A D GG A +QI +TD N+ PVF Y ++ E+ P Sbjct: 2611 KENLDFEKTKNYEISVQAKDGGGLVSHAKINIQITVTDFNDNFPVFTQEVYKVNIHENIP 2670 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 I +TVL V+A+D D GINAQITYS + +N + F INP++G ITT +D E Sbjct: 2671 IHSTVLQVNASDKDEGINAQITYSFGTTATNVL-----RIFAINPKSGEITTKGNVDFEE 2725 Query: 544 MSGYLLTVTARDG--GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 Y ++V A+DG G P+LS + + ++D+NDN P F++ Y A + E+ G S+ Sbjct: 2726 TKYYDISVQAQDGDKGSPTLSSLKTIRLDILDINDNPPKFEKSNYVAYVTENNQPGASIY 2785 Query: 602 QVGATDADVGLNGRIHYELDPKDREEGS-----FVIDPASGVIRTNKALDRESVATHDLK 656 + A D D NG++ Y + + + F I+P +G I T +D E V +D+ Sbjct: 2786 SIQAIDEDTEENGKVVYSIFTNNTTSANNVHRIFSINPNNGEITTKGNVDFEEVKYYDIS 2845 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 A DGG+ S V++ + DIND+PP FE Y++EN+ G++I I+A D D Sbjct: 2846 VEAQDGGSLVSHSKVLIQ-NVSDINDNPPKFEKSNYVAYVTENNQPGSSIFSIKAIDKDT 2904 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPP 773 N V YSI S + LD E+ + +EL++ A+ +P Sbjct: 2905 EENGKVVYSISNNTVEFSSVSYISINPVTGFVTNQTSLDRET-QSNHELILTASDGGNPV 2963 Query: 774 LWNDVRVEILVTDVNDNAPV 793 ++I VTDVNDN PV Sbjct: 2964 QTGTTLIKITVTDVNDNFPV 2983 Score = 386 bits (949), Expect = e-105 Identities = 233/688 (33%), Positives = 364/688 (52%), Gaps = 43/688 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVE-YTIELVTAD 68 +I V D ND+ PVF + Y+ V E ++ GT V ++ D D G+N EV + + +V Sbjct: 2971 KITVTDVNDNFPVFTQEVYKTPVSEDSTLGTVVALIEGHDLDSGENGEVICHIVGMVPFK 3030 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 L+ G ++T ++LDREK + Y + ++ATD+ SP Sbjct: 3031 LLSSS--------------------GNFYKIVTTSTLDREKNSHYNITIQATDKGSPP-- 3068 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 LS TI ++I D NDN P F + TYT + S ++ K+ A DAD G N+ + Sbjct: 3069 -LSFQKTIRLDISDINDNAPVFEKSTYTYEM-VPFSSEQGTLVTKVVAVDADSGHNAWLS 3126 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y + + F ID +G++ +LD E ++ L++ A DGG+P ++ TT + I + Sbjct: 3127 YHFLQDSETSHFIIDQYTGEIRTSTSLDRETQSNHELILTASDGGNPVQTGTTLIKITVT 3186 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D NDN P F +++ ++ EN+P+ +I V A D DEG+NA++TY+ + + NV Sbjct: 3187 DFNDNLPEFTQEVYKVNIHENIPLNSTIFHVNASDKDEGINAQITYSFSST--SNNVLRI 3244 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 +I P++G + T G LD+E + Y + + ATD G PP S T F Sbjct: 3245 FSIHPKNGAIKTKGTLDKEKNSHYNITIQATDKGSPPLSYQKTIRLDVLDINDNSPVFEK 3304 Query: 369 GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSIT--SQNG-RGLI 423 QY + E+ PG + ++ A D D E+ +L Y I NT SI+ S N G+I Sbjct: 3305 SQYIAYVPENNQPGASIFSIQAIDKDTEENGKLLYSIITRNTEEMPSISYISINPVTGVI 3364 Query: 424 TVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFED 481 + D++Q+R + + + A D+G + +A+V+I +TD N+ PVF Y ++ E+ Sbjct: 3365 YAQRSFDYEQDREFKIQIMAKDNGSPPLNSSAIVRITVTDFNDNFPVFTQEVYKVNIHEN 3424 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 PI +TVL V+A+D D GINAQITYS S+ +N + F INPQ G I LDR Sbjct: 3425 IPINSTVLHVNASDKDEGINAQITYSFSTTSANVL-----RMFYINPQNGEIKIKGTLDR 3479 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 E S Y +T+ A D G P LS + + V+D+NDN PVF++ Y A + E+ G S+ Sbjct: 3480 ERSSHYNITIQATDKGSPPLSSWKTIALEVLDINDNSPVFEKSTYIAYVPENNQPGASIY 3539 Query: 602 QVGATDADVGLNGRIHYELDPKDREE---GSFV-IDPASGVIRTNKALDRESVATHDLKA 657 + A D D NG++ Y + + EE S++ I+P +GVI ++ D E +++ Sbjct: 3540 SIQAIDKDTEENGKLFYSIITSNTEELSSTSYISINPVTGVIYAQRSFDYEQDREFEIQI 3599 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPP 685 +A D G+PP +S+ IV I + D ND+ P Sbjct: 3600 IAKDNGSPPLNSSTIVRICVVDQNDNSP 3627 Score = 385 bits (947), Expect = e-104 Identities = 273/886 (30%), Positives = 435/886 (49%), Gaps = 53/886 (5%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 I+ QI V D ND+ PVF + Y+ ++ E +TVL + A+D+D G NA++ Y+ Sbjct: 2640 INIQITVTDFNDNFPVFTQEVYKVNIHENIPIHSTVLQVNASDKDEGINAQITYSFGTTA 2699 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 + L +F I+ +SG + T+ ++D E+ Y + V+A D Sbjct: 2700 TNVLR-----------------IFAINPKSGEITTKGNVDFEETKYYDISVQAQD-GDKG 2741 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 S LSS TI ++I+D NDN P+F + Y V E+ I I+A D D N Sbjct: 2742 SPTLSSLKTIRLDILDINDNPPKFEKSNYVAYVTENNQ--PGASIYSIQAIDEDTEENGK 2799 Query: 187 IRYAIIGGNTQMQ------FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240 + Y+I NT FSI+ +G+++ +D+E+V+ Y + + AQDGGS S++ Sbjct: 2800 VVYSIFTNNTTSANNVHRIFSINPNNGEITTKGNVDFEEVKYYDISVEAQDGGS-LVSHS 2858 Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 L+ N+ D+NDN P+F S + V+EN G SI ++A D D N ++ Y++++ Sbjct: 2859 KVLIQNVSDINDNPPKFEKSNYVAYVTENNQPGSSIFSIKAIDKDTEENGKVVYSISNNT 2918 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 + I+I+P +G+V LDRETQ+ ++L++TA+DGG+P ++ T Sbjct: 2919 VEFSSVSYISINPVTGFVTNQTSLDRETQSNHELILTASDGGNPVQTGTTLIKITVTDVN 2978 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQN 418 F Y+ ++ED GT V + D D E+ + I G F + S + Sbjct: 2979 DNFPVFTQEVYKTPVSEDSTLGTVVALIEGHDLDSGENGEVICHIVG---MVPFKLLSSS 3035 Query: 419 GRGL-ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYT 475 G I LD ++ Y +T+ ATD G S ++++I+D N+ APVFE + YT Sbjct: 3036 GNFYKIVTTSTLDREKNSHYNITIQATDKGSPPLSFQKTIRLDISDINDNAPVFEKSTYT 3095 Query: 476 ASVFE-DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 + + GT V V A D+D G NA ++Y + + +H F+I+ TG I Sbjct: 3096 YEMVPFSSEQGTLVTKVVAVDADSGHNAWLSYHF---LQDSETSH----FIIDQYTGEIR 3148 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 T+ LDRET S + L +TA DGG P + TT ++I+V D NDN P F Q++Y NI E+ Sbjct: 3149 TSTSLDRETQSNHELILTASDGGNPVQTGTTLIKITVTDFNDNLPEFTQEVYKVNIHENI 3208 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREE-GSFVIDPASGVIRTNKALDRESVATH 653 + +++ V A+D D G+N +I Y F I P +G I+T LD+E + + Sbjct: 3209 PLNSTIFHVNASDKDEGINAQITYSFSSTSNNVLRIFSIHPKNGAIKTKGTLDKEKNSHY 3268 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713 ++ A D G+PP S + + + DIND+ PVFE Y+ EN+ G +I I+A D Sbjct: 3269 NITIQATDKGSPPLSYQKTIRLDVLDINDNSPVFEKSQYIAYVPENNQPGASIFSIQAID 3328 Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV-TMVDLDYESPRK-KYELVIR-AA 770 D N + YSI + S+ + ++ DYE R+ K +++ + Sbjct: 3329 KDTEENGKLLYSIITRNTEEMPSISYISINPVTGVIYAQRSFDYEQDREFKIQIMAKDNG 3388 Query: 771 SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPAYDAD--VTDKL 827 SPPL + V I VTD NDN PV ++ N + P+ V A D D + ++ Sbjct: 3389 SPPLNSSAIVRITVTDFNDNFPVFTQ-EVYKVNIHENIPINSTVLHVNASDKDEGINAQI 3447 Query: 828 QYRI--LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 Y S N + +N G + + L+ + + TD Sbjct: 3448 TYSFSTTSANVLRMFYINPQNGEIKIKGTLDRERSSHYNITIQATD 3493 Score = 383 bits (942), Expect = e-104 Identities = 267/898 (29%), Positives = 440/898 (48%), Gaps = 52/898 (5%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I V D ND+ P+F + Y+ S+ E +TVL + A+D+D G N+++ Y+ + Sbjct: 2324 RITVTDANDNFPMFSQEIYKVSINENMPLNSTVLYVSASDKDEGINSQLTYSFSSASKQA 2383 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N F I+ +SG ++T ++LDRE + Y + ++ATD+ SP Sbjct: 2384 TN-----------------AFAINPQSGEIVTSSTLDREMKSHYDITIQATDKGSPP--- 2423 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LSS TI +++ D NDN P F + TY V + E+ I I+A+D D N+ + Y Sbjct: 2424 LSSRKTIRLDVSDINDNAPVFEKSTYIVYISENNE--PGASIYSIQASDKDSEENAKLVY 2481 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 + I N + IDS ++ L L+ E + +V+ A DGGSP ++ T + I + D Sbjct: 2482 SSITSNREENLRIDSDISELVLEIPLNRETESIHEIVLTAFDGGSPMQTGTALIRITVTD 2541 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 +NDN P F ++ S++EN+P+ +++ V A D D+G+N+++TY+ + + Sbjct: 2542 MNDNFPIFGQEVYTVSINENIPLNSTVLCVSANDKDQGINSQITYSFSAT--SKQASRSF 2599 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 +I+ +G + T LD E Y++ V A DGG A F Sbjct: 2600 SINSETGEIKTKENLDFEKTKNYEISVQAKDGGGLVSHAKINIQITVTDFNDNFPVFTQE 2659 Query: 370 QYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI--TGGNTRGRFSITSQNGRGLITV 425 Y+V + E+ P + V+ + A+D DE + ++ Y T N F+I ++G IT Sbjct: 2660 VYKVNIHENIPIHSTVLQVNASDKDEGINAQITYSFGTTATNVLRIFAINPKSGE--ITT 2717 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAM----VQINITDANNYAPVFENAPYTASVFED 481 +DF++ + Y ++V A D S T ++++I D N+ P FE + Y A V E+ Sbjct: 2718 KGNVDFEETKYYDISVQAQDGDKGSPTLSSLKTIRLDILDINDNPPKFEKSNYVAYVTEN 2777 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 G ++ + A D D N ++ YS+ + + A H + F INP G ITT +D Sbjct: 2778 NQPGASIYSIQAIDEDTEENGKVVYSIFTNNTTSANNVH-RIFSINPNNGEITTKGNVDF 2836 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEI-SVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 E + Y ++V A+DGG SL + V I +V D+NDN P F++ Y A + E+ G+S+ Sbjct: 2837 EEVKYYDISVEAQDGG--SLVSHSKVLIQNVSDINDNPPKFEKSNYVAYVTENNQPGSSI 2894 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGS---FVIDPASGVIRTNKALDRESVATHDLKA 657 + A D D NG++ Y + E S I+P +G + +LDRE+ + H+L Sbjct: 2895 FSIKAIDKDTEENGKVVYSISNNTVEFSSVSYISINPVTGFVTNQTSLDRETQSNHELIL 2954 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A DGG P Q+ T ++ I + D+ND+ PVF + +SE+S +GT + I HD D G Sbjct: 2955 TASDGGNPVQTGTTLIKITVTDVNDNFPVFTQEVYKTPVSEDSTLGTVVALIEGHDLDSG 3014 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPL 774 N V I G F L + G+ ++VT LD E Y + I+A SPPL Sbjct: 3015 ENGEVICHIVG---MVPFKLLSSSGNFY-KIVTTSTLDREK-NSHYNITIQATDKGSPPL 3069 Query: 775 WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDK--LQYRI 831 + + ++D+NDNAPV + + G +V A DAD L Y Sbjct: 3070 SFQKTIRLDISDINDNAPVFEKSTYTYEMVPFSSEQGTLVTKVVAVDADSGHNAWLSYHF 3129 Query: 832 LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889 L + + ++++ TG + S L+ + ++ +DG N ++ L +T+ Sbjct: 3130 LQDSETSHFIIDQYTGEIRTSTSLDRETQSNHELILTASDGGNPVQTGTTLIKITVTD 3187 Score = 380 bits (934), Expect = e-103 Identities = 256/804 (31%), Positives = 408/804 (50%), Gaps = 62/804 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +++V D ND++PVFE Y + E G ++ +++A+D+D +NA++ Y+ + T Sbjct: 2431 RLDVSDINDNAPVFEKSTYIVYISENNEPGASIYSIQASDKDSEENAKLVYS-----SIT 2485 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N E+ RID L+ L+RE + + +++ A D SP+ Sbjct: 2486 SNREEN--------------LRIDSDISELVLEIPLNRETESIHEIVLTAFDGGSPMQ-- 2529 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + TA I + + D NDN+P F ++ YTVS++E+I + N + + A D D G NS I Y Sbjct: 2530 -TGTALIRITVTDMNDNFPIFGQEVYTVSINENIPL--NSTVLCVSANDKDQGINSQITY 2586 Query: 190 AIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 + + Q FSI+S +G++ + LD+E+ ++Y + ++A+DGG + I + Sbjct: 2587 SFSATSKQASRSFSINSETGEIKTKENLDFEKTKNYEISVQAKDGGGLVSHAKINIQITV 2646 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 D NDN P F +++ ++ EN+PI ++++V A D DEG+NA++TY+ NV Sbjct: 2647 TDFNDNFPVFTQEVYKVNIHENIPIHSTVLQVNASDKDEGINAQITYSFGTT--ATNVLR 2704 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG--GDPPRSATATXXXXXXXXXXXXXX 365 I+P+SG + T G +D E Y + V A DG G P S+ T Sbjct: 2705 IFAINPKSGEITTKGNVDFEETKYYDISVQAQDGDKGSPTLSSLKTIRLDILDINDNPPK 2764 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGR------FSITSQ 417 F Y + E+ PG + ++ A D D E+ ++ Y I NT FSI Sbjct: 2765 FEKSNYVAYVTENNQPGASIYSIQAIDEDTEENGKVVYSIFTNNTTSANNVHRIFSINPN 2824 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQI-NITDANNYAPVFENAPYTA 476 NG IT +DF++ + Y ++V A D G + V I N++D N+ P FE + Y A Sbjct: 2825 NGE--ITTKGNVDFEEVKYYDISVEAQDGGSLVSHSKVLIQNVSDINDNPPKFEKSNYVA 2882 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV-INPQTGAITT 535 V E+ G+++ + A D D N ++ YS ISN V ++ INP TG +T Sbjct: 2883 YVTENNQPGSSIFSIKAIDKDTEENGKVVYS----ISNNTVEFSSVSYISINPVTGFVTN 2938 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 LDRET S + L +TA DGG P + TT ++I+V DVNDN PVF Q++Y + ED+ Sbjct: 2939 QTSLDRETQSNHELILTASDGGNPVQTGTTLIKITVTDVNDNFPVFTQEVYKTPVSEDST 2998 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG---VIRTNKALDRESVAT 652 +GT V+ + D D G NG + + F + +SG I T LDRE + Sbjct: 2999 LGTVVALIEGHDLDSGENGEVICHIVGM----VPFKLLSSSGNFYKIVTTSTLDREKNSH 3054 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF-YISENSPIGTTIGEIRA 711 +++ A D G+PP S + + I DIND+ PVFE T+ + +S GT + ++ A Sbjct: 3055 YNITIQATDKGSPPLSFQKTIRLDISDINDNAPVFEKSTYTYEMVPFSSEQGTLVTKVVA 3114 Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA- 770 D D G NA + Y +++ F ++ G E+ T LD E+ + +EL++ A+ Sbjct: 3115 VDADSGHNAWLSYHFLQDSETSHFIIDQYTG----EIRTSTSLDRET-QSNHELILTASD 3169 Query: 771 --SPPLWNDVRVEILVTDVNDNAP 792 +P ++I VTD NDN P Sbjct: 3170 GGNPVQTGTTLIKITVTDFNDNLP 3193 Score = 380 bits (934), Expect = e-103 Identities = 269/868 (30%), Positives = 423/868 (48%), Gaps = 70/868 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++++LD ND+ P FE Y A V E G ++ +++A D+D +N +V Y+I T +T Sbjct: 2752 RLDILDINDNPPKFEKSNYVAYVTENNQPGASIYSIQAIDEDTEENGKVVYSI--FTNNT 2809 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + + V +F I+ +G + T+ ++D E+V Y + V+A D S VS Sbjct: 2810 TSANN-----------VHRIFSINPNNGEITTKGNVDFEEVKYYDISVEAQDGGSLVSH- 2857 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + + N+ D NDN P+F + Y V E+ + I IKA D D N + Y Sbjct: 2858 ---SKVLIQNVSDINDNPPKFEKSNYVAYVTENNQPGSS--IFSIKAIDKDTEENGKVVY 2912 Query: 190 AIIGGNTQMQ----FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 +I + SI+ ++G V+ +LD E ++ L++ A DGG+P ++ TT + I Sbjct: 2913 SISNNTVEFSSVSYISINPVTGFVTNQTSLDRETQSNHELILTASDGGNPVQTGTTLIKI 2972 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 + DVNDN P F +++ VSE+ +G + ++ +D D G N E+ + Sbjct: 2973 TVTDVNDNFPVFTQEVYKTPVSEDSTLGTVVALIEGHDLDSGENGEVICHIVGM------ 3026 Query: 306 DLPITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 +P + SG Y T+ LDRE + Y + + ATD G PP S T Sbjct: 3027 -VPFKLLSSSGNFYKIVTTSTLDREKNSHYNITIQATDKGSPPLSFQKTIRLDISDINDN 3085 Query: 363 XXXFMPGQYEVELAE-DEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNG 419 F Y E+ GT V + A DAD + L Y + F I G Sbjct: 3086 APVFEKSTYTYEMVPFSSEQGTLVTKVVAVDADSGHNAWLSYHFLQDSETSHFIIDQYTG 3145 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTAS 477 I + LD + + + L ++A+D G ++ T +++I +TD N+ P F Y + Sbjct: 3146 E--IRTSTSLDRETQSNHELILTASDGGNPVQTGTTLIKITVTDFNDNLPEFTQEVYKVN 3203 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 + E+ P+ +T+ V+A+D D GINAQITYS SS +N + F I+P+ GAI T Sbjct: 3204 IHENIPLNSTIFHVNASDKDEGINAQITYSFSSTSNNVL-----RIFSIHPKNGAIKTKG 3258 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LD+E S Y +T+ A D G P LS + + V+D+NDN PVF++ Y A + E+ G Sbjct: 3259 TLDKEKNSHYNITIQATDKGSPPLSYQKTIRLDVLDINDNSPVFEKSQYIAYVPENNQPG 3318 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEG---SFV-IDPASGVIRTNKALDRESVATH 653 S+ + A D D NG++ Y + ++ EE S++ I+P +GVI ++ D E Sbjct: 3319 ASIFSIQAIDKDTEENGKLLYSIITRNTEEMPSISYISINPVTGVIYAQRSFDYEQDREF 3378 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713 ++ +A D G+PP +S+ IV I + D ND+ PVF + I EN PI +T+ + A D Sbjct: 3379 KIQIMAKDNGSPPLNSSAIVRITVTDFNDNFPVFTQEVYKVNIHENIPINSTVLHVNASD 3438 Query: 714 PDEGPNAVVHYSIK--GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA-- 769 DEG NA + YS + F + + G E+ LD E Y + I+A Sbjct: 3439 KDEGINAQITYSFSTTSANVLRMFYINPQNG----EIKIKGTLDRER-SSHYNITIQATD 3493 Query: 770 -ASPPL--WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD- 825 SPPL W + +E+L D+NDN+PV + I ++ P + A D D + Sbjct: 3494 KGSPPLSSWKTIALEVL--DINDNSPVFEKSTYIAYVPENNQPGASIYSIQAIDKDTEEN 3551 Query: 826 -KLQYRILSGNNANL-----ILLNETTG 847 KL Y I++ N L I +N TG Sbjct: 3552 GKLFYSIITSNTEELSSTSYISINPVTG 3579 Score = 379 bits (933), Expect = e-103 Identities = 260/863 (30%), Positives = 420/863 (48%), Gaps = 61/863 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I V D ND+ P+F + Y S+ E +TVL + A D+D G N+++ Y+ + Sbjct: 2536 RITVTDMNDNFPIFGQEVYTVSINENIPLNSTVLCVSANDKDQGINSQITYSFSATSKQA 2595 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 F I+ +G + T+ +LD EK Y + V+A D VS Sbjct: 2596 SRS-----------------FSINSETGEIKTKENLDFEKTKNYEISVQAKDGGGLVSH- 2637 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + I + + D NDN+P F+++ Y V++ E+I + + + ++ A+D D G N+ I Y Sbjct: 2638 --AKINIQITVTDFNDNFPVFTQEVYKVNIHENIPI--HSTVLQVNASDKDEGINAQITY 2693 Query: 190 AI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG--GSPSRSNTTQLLI 245 + N F+I+ SG+++ +D+E+ + Y + ++AQDG GSP+ S+ + + Sbjct: 2694 SFGTTATNVLRIFAINPKSGEITTKGNVDFEETKYYDISVQAQDGDKGSPTLSSLKTIRL 2753 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-- 303 +I D+NDN P+F S + V+EN G SI +QA D D N ++ Y++ + T Sbjct: 2754 DILDINDNPPKFEKSNYVAYVTENNQPGASIYSIQAIDEDTEENGKVVYSIFTNNTTSAN 2813 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 NV +I+P +G + T G +D E Y + V A DGG S + Sbjct: 2814 NVHRIFSINPNNGEITTKGNVDFEEVKYYDISVEAQDGGSLV-SHSKVLIQNVSDINDNP 2872 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTR-GRFSITSQNG- 419 F Y + E+ PG+ + ++ A D D E+ ++ Y I+ S S N Sbjct: 2873 PKFEKSNYVAYVTENNQPGSSIFSIKAIDKDTEENGKVVYSISNNTVEFSSVSYISINPV 2932 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTAS 477 G +T LD + + + L ++A+D G ++ T +++I +TD N+ PVF Y Sbjct: 2933 TGFVTNQTSLDRETQSNHELILTASDGGNPVQTGTTLIKITVTDVNDNFPVFTQEVYKTP 2992 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 V ED+ +GT V ++ D D G N ++ + + + ++ + I T Sbjct: 2993 VSEDSTLGTVVALIEGHDLDSGENGEVICHIVGMVPFKLLSSSGNFY-------KIVTTS 3045 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME-DALV 596 LDRE S Y +T+ A D G P LS + + + D+NDN PVF++ YT ++ + Sbjct: 3046 TLDREKNSHYNITIQATDKGSPPLSFQKTIRLDISDINDNAPVFEKSTYTYEMVPFSSEQ 3105 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 GT V++V A DAD G N + Y +D E F+ID +G IRT+ +LDRE+ + H+L Sbjct: 3106 GTLVTKVVAVDADSGHNAWLSYHF-LQDSETSHFIIDQYTGEIRTSTSLDRETQSNHELI 3164 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 A DGG P Q+ T ++ I + D ND+ P F + I EN P+ +TI + A D DE Sbjct: 3165 LTASDGGNPVQTGTTLIKITVTDFNDNLPEFTQEVYKVNIHENIPLNSTIFHVNASDKDE 3224 Query: 717 GPNAVVHYSIKGGDDS--NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---AS 771 G NA + YS ++ FS+ + G+ K T LD E Y + I+A S Sbjct: 3225 GINAQITYSFSSTSNNVLRIFSIHPKNGAIK----TKGTLDKEK-NSHYNITIQATDKGS 3279 Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQY 829 PPL + + V D+NDN+PV + Q I ++ P + A D D + KL Y Sbjct: 3280 PPLSYQKTIRLDVLDINDNSPVFEKSQYIAYVPENNQPGASIFSIQAIDKDTEENGKLLY 3339 Query: 830 RILSGNNANL-----ILLNETTG 847 I++ N + I +N TG Sbjct: 3340 SIITRNTEEMPSISYISINPVTG 3362 Score = 377 bits (927), Expect = e-102 Identities = 277/910 (30%), Positives = 459/910 (50%), Gaps = 68/910 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 QI V D ND+ PVF Y S+ E + G+ VL + A+ NA++ Y+I +T Sbjct: 1673 QIIVTDANDNLPVFTEVLYTVSISENTAVGSVVLCVNASS-----NAKITYSIS--ETNT 1725 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 ++P F I+ +G L + S D E+ ++ + + A D P S Sbjct: 1726 MSP----------------YFSINIETGVLYAQQSFDYEQHKQFEMEIMAKDNGFP-SMT 1768 Query: 130 LSSTATIH----VNIIDDNDNYPQFSEKTYTVSVDEDISVTD----NPVIAKI-KATDAD 180 ++T IH V + D NDN P F+E+ YTVS+ E+ V N KI +A+D D Sbjct: 1769 SNTTLLIHIIDRVVVTDANDNAPVFTEEVYTVSISENAPVNAIVLCNDNAPKIVQASDLD 1828 Query: 181 VGANSAIRYAIIGGNTQM-----QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP 235 G NS + Y++ NT+ FSI+ +G + ++ DYEQ + + + ++A+D G P Sbjct: 1829 TGENSKVIYSVFNTNTEAFPVSSYFSINIETGVLYAQRSFDYEQHKEFAMHVQAKDNGYP 1888 Query: 236 S-RSNTTQLL-INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293 S +S+ + + ++I DVNDN P F SL+ + EN G SI V A D D G NA+L Sbjct: 1889 SHQSHKWKFIKLDISDVNDNPPVFRKSLYTTYLPENNLPGASIYTVHATDVDSGDNAKLI 1948 Query: 294 YTMTDKDYTGNVDLP-ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352 Y++++ D P I+ R + T+ LDRE Y + + ATD G P R++ Sbjct: 1949 YSISN---ANTEDFPLISSTGRFYRIVTTNNLDRERTPFYNITILATDRGYPQRTSKKMI 2005 Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRF 412 F+ Y+ L E+ PG + +L A D D + + NT F Sbjct: 2006 GVEISDVNDNAPLFIKPTYDAFLPENNLPGALIYSLHAKDLDVGDNAKVTYSILNTNTDF 2065 Query: 413 SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFE 470 S++S + T A PLD + E + L ++A D G ++ TA+++I ++D N+ AP+F Sbjct: 2066 SVSSYFSINIETGA-PLDRETESIHELVLTAFDGGNPVQTGTAIIKIIVSDFNDNAPIFT 2124 Query: 471 NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 YT S+ E+ P+ +T+L VSA D D G N+QITY ++ S +A+ F+I+ + Sbjct: 2125 QEVYTVSLNENIPVNSTILRVSANDKDEGSNSQITYYFAAS-SKQAM----NTFIIDSIS 2179 Query: 531 GAITTNKLLDRETMS-GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589 G + T + LD E + + + + A+D G PSL+ +T++ I +VD NDN PVF Q++Y + Sbjct: 2180 GEVKTKENLDFEKIEREFQIQIMAKDHGSPSLNSSTNLRICIVDFNDNLPVFSQEVYKVS 2239 Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNKALDRE 648 I E+ + +++ V A D D G+N +I Y ++ +F+I+ SG I T + LD E Sbjct: 2240 INENIPINSTILYVSANDKDEGINSQIRYYFSTSSKQILNTFIINSISGAIMTKENLDFE 2299 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 +++ A D T ++ T ++ I + D ND+ P+F + I+EN P+ +T+ Sbjct: 2300 KTKLYEISVQANDQYT-GETGTALIRITVTDANDNFPMFSQEIYKVSINENMPLNSTVLY 2358 Query: 709 IRAHDPDEGPNAVVHYSIKGGDD--SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV 766 + A D DEG N+ + YS +N+F++ + G E+VT LD E + Y++ Sbjct: 2359 VSASDKDEGINSQLTYSFSSASKQATNAFAINPQSG----EIVTSSTLDREM-KSHYDIT 2413 Query: 767 IRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV 823 I+A SPPL + + + V+D+NDNAPV + I ++ P + A D D Sbjct: 2414 IQATDKGSPPLSSRKTIRLDVSDINDNAPVFEKSTYIVYISENNEPGASIYSIQASDKDS 2473 Query: 824 TD--KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQ 881 + KL Y ++ N + ++ + L LN + + ++ DG + ++ Sbjct: 2474 EENAKLVYSSITSNREENLRIDSDISELVLEIPLNRETESIHEIVLTAFDGGSPMQTGTA 2533 Query: 882 LSVRLITEEM 891 L +R+ +M Sbjct: 2534 L-IRITVTDM 2542 Score = 376 bits (925), Expect = e-102 Identities = 270/918 (29%), Positives = 435/918 (47%), Gaps = 65/918 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT- 69 I V D ND+ PVF Q Y+ S+ E A +TV + ATD+D G N + Y+ + Sbjct: 569 IIVTDYNDNVPVFTQQVYKISISESAPINSTVTVVTATDKDDGTNGHITYSFSRTAENAF 628 Query: 70 ------LNPEDAXXXXXXXXXXVQDVFR-------IDGRSGALLTRASLDREKVARYTVL 116 +NP + + + I +G + T + + ++ V+ Sbjct: 629 HTQMFNINPANGEIKTKVDADSGHNSWLSYHFIQIISQHTGEIRTSRMFQEKDILKHKVV 688 Query: 117 VKATDQASPVSDRLSSTATIHVNIIDDNDNY-PQF--------SEKTYTVSVDEDISVTD 167 + D P LS+T T+ + + D + PQ S K Y VSV E+ + Sbjct: 689 IMVKDNGDP---SLSATVTLSLAVGDHFQHVVPQINNEFNDGPSSKVYKVSVSENAPINS 745 Query: 168 NPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVI 227 +I + ATD D G N+ I Y+I + ++ID +G++ L LD E ++ L + Sbjct: 746 TVII--LTATDKDEGTNAKITYSISKTSKNNFYTIDLDNGNLVLENPLDREMQSTHELTL 803 Query: 228 RAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG 287 A DGG+P R+ T + I + DVNDN P F ++++ S+SEN P+ +++ V A D DEG Sbjct: 804 TAFDGGTPVRTGTALIKITVTDVNDNVPVFTQAVYKASISENSPVNTTVLYVNATDKDEG 863 Query: 288 VNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRS 347 +NA++ Y+ + + ++DL +SG +Y LDRETQ ++L++TA+DGG+P RS Sbjct: 864 INAQIVYSFSVSEKYFSIDL------QSGMLYVKKPLDRETQTIHELILTASDGGNPVRS 917 Query: 348 ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH----YEI 403 TA F Y+V ++E+ P + V+T+ ATD DE + Sbjct: 918 GTALIRIAVTDSNDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQIMYSFSK 977 Query: 404 TGGNT--RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINI 459 T GN FSI +G I Q +F+ ++ Y ++V A D G S A + I I Sbjct: 978 TSGNNLHTSMFSINYTSGE--IKTKQNFNFEAKKFYEISVYAKDYGSPSLSCNASLTIRI 1035 Query: 460 TDANNYAP--VFENAPYTASVFEDAPI----GTTVLVVSATDSDVGINAQITYSLSSEIS 513 TD N+ P ++ ++ S FE P+ G + V A D+D G NA ++Y + Sbjct: 1036 TDQNDNVPKILYPSSESVDSSFEMVPVASEQGALITKVVAVDADSGHNAWLSYHV----- 1090 Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 F I+ TG I T++ LDRE + Y +T+ A D G P LS+ +++ + D Sbjct: 1091 --VQGSEPSLFSISQNTGEIRTSRSLDREKVPWYNITIQATDRGSPHLSNIKLIKLDISD 1148 Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633 VNDN PVF + Y A I E+ L G S+ ++ A+D D G N ++ Y + + E F I Sbjct: 1149 VNDNAPVFTKSSYVAYIAENNLAGASIYRIQASDIDAGDNAKLSYHV-VQGSEPSLFSIS 1207 Query: 634 PASGVIRTN-KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692 +G IRT+ K LDRE+ + H+L A DGG P ++ T ++ I + D ND+ PVF + Sbjct: 1208 QNTGEIRTSQKPLDRETQSIHELILTASDGGNPLRTGTALIRIIVTDSNDNLPVFTQEVY 1267 Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752 ISEN+PI +++ + A D DEG NA + YSI ++N ++ E+ V Sbjct: 1268 KVSISENAPINSSVIILTATDKDEGTNAQITYSISKTSENNFYTSVFNINPVMGEITIKV 1327 Query: 753 DLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-G 811 R +P + ++VTD NDN PV ++ + + P+ Sbjct: 1328 STSSSYYRIITTTASDGGTPVRTGTALIRVIVTDANDNTPVFTQ-EVYKVSISENTPINS 1386 Query: 812 PFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 RV A D D Q + +N + L L+ + + + ++ +D Sbjct: 1387 TVLRVNASDMDEGTNAQITYSFSRTS----VNSLHAKLVLERPLDREIKNIHELLLTASD 1442 Query: 872 GVNEIKAMMQLSVRLITE 889 G ++ L ++T+ Sbjct: 1443 GGTPVRTGTALIRVIVTD 1460 Score = 366 bits (900), Expect = 5e-99 Identities = 268/878 (30%), Positives = 440/878 (50%), Gaps = 97/878 (11%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++++ D ND++PVF Y A + E +G ++ ++A+D D G NA++ Y + + + Sbjct: 1143 KLDISDVNDNAPVFTKSSYVAYIAENNLAGASIYRIQASDIDAGDNAKLSYHVVQGSEPS 1202 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLT-RASLDREKVARYTVLVKATDQASPVSD 128 L F I +G + T + LDRE + + +++ A+D +P+ Sbjct: 1203 L-------------------FSISQNTGEIRTSQKPLDRETQSIHELILTASDGGNPLR- 1242 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 + TA I + + D NDN P F+++ Y VS+ E+ + + +I + ATD D G N+ I Sbjct: 1243 --TGTALIRIIVTDSNDNLPVFTQEVYKVSISENAPINSSVII--LTATDKDEGTNAQIT 1298 Query: 189 YAIIGGNTQ----MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 Y+I + F+I+ + G++++ + R + A DGG+P R+ T + Sbjct: 1299 YSISKTSENNFYTSVFNINPVMGEITIKVSTSSSYYRI--ITTTASDGGTPVRTGTALIR 1356 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + + D NDN P F +++ S+SEN PI +++RV A D DEG NA++TY+ + + + Sbjct: 1357 VIVTDANDNTPVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFS-RTSVNS 1415 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 + + ++ LDRE + ++LL+TA+DGG P R+ TA Sbjct: 1416 LHAKLVLER---------PLDREIKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTP 1466 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH----YEITGGNT--RGRFSITSQN 418 F Y+V ++E+ P + V+ + A+D DE + T N+ FSI + Sbjct: 1467 VFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSENSLHASMFSINPTS 1526 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTA 476 G I +PLD + + + L ++A+D G R+ TA++++ +TDAN+ PVF Y Sbjct: 1527 GE--IKTKRPLDRETKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKV 1584 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 S+ E+ PI +TVL V+A+D D G NAQITYS S N H F INP +G ITT Sbjct: 1585 SISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVNSL---HASMFSINPTSGEITTK 1641 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 K LDRE + + L +TA DGG P + T ++I V D NDN PVF + LYT +I E+ V Sbjct: 1642 KPLDREAQTSHELILTASDGGNPVRTGTALIQIIVTDANDNLPVFTEVLYTVSISENTAV 1701 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 G+ V V A+ N +I Y + + F I+ +GV+ ++ D E +++ Sbjct: 1702 GSVVLCVNASS-----NAKITYSISETNTMSPYFSINIETGVLYAQQSFDYEQHKQFEME 1756 Query: 657 AVAIDGGTPPQSS--TVIVHI----KIEDINDSPPVFESDCLTFYISENSPIGTTI---- 706 +A D G P +S T+++HI + D ND+ PVF + T ISEN+P+ + Sbjct: 1757 IMAKDNGFPSMTSNTTLLIHIIDRVVVTDANDNAPVFTEEVYTVSISENAPVNAIVLCND 1816 Query: 707 ---GEIRAHDPDEGPNAVVHYSIKGGDD-----SNSFSLETRQGSDKAELVTMVDLDYES 758 ++A D D G N+ V YS+ + S+ FS+ G L DYE Sbjct: 1817 NAPKIVQASDLDTGENSKVIYSVFNTNTEAFPVSSYFSINIETG----VLYAQRSFDYEQ 1872 Query: 759 PRKKYELVIRAA-------SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY--KDCFP 809 K++ + ++A W ++++I +DVNDN PV + + ++ Y ++ P Sbjct: 1873 -HKEFAMHVQAKDNGYPSHQSHKWKFIKLDI--SDVNDNPPVFR--KSLYTTYLPENNLP 1927 Query: 810 VGPFGRVPAYDADVTD--KLQYRILSGNNANLILLNET 845 V A D D D KL Y I + N + L++ T Sbjct: 1928 GASIYTVHATDVDSGDNAKLIYSISNANTEDFPLISST 1965 Score = 363 bits (893), Expect = 4e-98 Identities = 251/798 (31%), Positives = 393/798 (49%), Gaps = 47/798 (5%) Query: 12 NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71 NV D ND+ P FE Y A V E G+++ ++KA D+D +N +V Y+I T + + Sbjct: 2864 NVSDINDNPPKFEKSNYVAYVTENNQPGSSIFSIKAIDKDTEENGKVVYSISNNTVEFSS 2923 Query: 72 PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131 I+ +G + + SLDRE + + +++ A+D +PV + Sbjct: 2924 VS---------------YISINPVTGFVTNQTSLDRETQSNHELILTASDGGNPVQ---T 2965 Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191 T I + + D NDN+P F+++ Y V ED ++ V+A I+ D D G N + I Sbjct: 2966 GTTLIKITVTDVNDNFPVFTQEVYKTPVSEDSTL--GTVVALIEGHDLDSGENGEVICHI 3023 Query: 192 IGGNTQMQFSIDSLSGD---VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 +G + F + S SG+ + TLD E+ Y + I+A D GSP S + ++I Sbjct: 3024 VG---MVPFKLLSSSGNFYKIVTTSTLDREKNSHYNITIQATDKGSPPLSFQKTIRLDIS 3080 Query: 249 DVNDNAPRFYTSLFQ-ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 D+NDNAP F S + E V + G + +V A DAD G NA L+Y T + Sbjct: 3081 DINDNAPVFEKSTYTYEMVPFSSEQGTLVTKVVAVDADSGHNAWLSYHFLQDSETSH--- 3137 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 ID +G + TS LDRETQ+ ++L++TA+DGG+P ++ T F Sbjct: 3138 -FIIDQYTGEIRTSTSLDRETQSNHELILTASDGGNPVQTGTTLIKITVTDFNDNLPEFT 3196 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI--TGGNTRGRFSITSQNGRGLI 423 Y+V + E+ P + + + A+D DE + ++ Y T N FSI +NG I Sbjct: 3197 QEVYKVNIHENIPLNSTIFHVNASDKDEGINAQITYSFSSTSNNVLRIFSIHPKNGA--I 3254 Query: 424 TVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFED 481 LD ++ Y +T+ ATD G S +++++ D N+ +PVFE + Y A V E+ Sbjct: 3255 KTKGTLDKEKNSHYNITIQATDKGSPPLSYQKTIRLDVLDINDNSPVFEKSQYIAYVPEN 3314 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 G ++ + A D D N ++ YS+ + + E + INP TG I + D Sbjct: 3315 NQPGASIFSIQAIDKDTEENGKLLYSIITRNTEEMPSI--SYISINPVTGVIYAQRSFDY 3372 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 E + + + A+D G P L+ + V I+V D NDN PVF Q++Y NI E+ + ++V Sbjct: 3373 EQDREFKIQIMAKDNGSPPLNSSAIVRITVTDFNDNFPVFTQEVYKVNIHENIPINSTVL 3432 Query: 602 QVGATDADVGLNGRIHYELDPKDREE-GSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 V A+D D G+N +I Y F I+P +G I+ LDRE + +++ A Sbjct: 3433 HVNASDKDEGINAQITYSFSTTSANVLRMFYINPQNGEIKIKGTLDRERSSHYNITIQAT 3492 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 D G+PP SS + +++ DIND+ PVFE Y+ EN+ G +I I+A D D N Sbjct: 3493 DKGSPPLSSWKTIALEVLDINDNSPVFEKSTYIAYVPENNQPGASIYSIQAIDKDTEENG 3552 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELV-TMVDLDYESPRKKYELVIRA---ASPPLWN 776 + YSI + S + ++ DYE R+ +E+ I A SPPL + Sbjct: 3553 KLFYSIITSNTEELSSTSYISINPVTGVIYAQRSFDYEQDRE-FEIQIIAKDNGSPPLNS 3611 Query: 777 DVRVEILVTDVNDNAPVM 794 V I V D NDN+P + Sbjct: 3612 STIVRICVVDQNDNSPTV 3629 Score = 358 bits (881), Expect = 1e-96 Identities = 278/906 (30%), Positives = 440/906 (48%), Gaps = 64/906 (7%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVL-------TLKATDQDIGKNAEVE 59 I ++ V D ND++PVF + Y S+ E A VL ++A+D D G+N++V Sbjct: 1777 IIDRVVVTDANDNAPVFTEEVYTVSISENAPVNAIVLCNDNAPKIVQASDLDTGENSKVI 1836 Query: 60 YTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKA 119 Y++ N E V F I+ +G L + S D E+ + + V+A Sbjct: 1837 YSV-----FNTNTE---------AFPVSSYFSINIETGVLYAQRSFDYEQHKEFAMHVQA 1882 Query: 120 TDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA 179 D P S + I ++I D NDN P F + YT + E + I + ATD Sbjct: 1883 KDNGYP-SHQSHKWKFIKLDISDVNDNPPVFRKSLYTTYLPE--NNLPGASIYTVHATDV 1939 Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPS 236 D G N+ + Y+I NT+ F + S +G + T LD E+ Y + I A D G P Sbjct: 1940 DSGDNAKLIYSISNANTE-DFPLISSTGRFYRIVTTNNLDRERTPFYNITILATDRGYPQ 1998 Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 R++ + + I DVNDNAP F + + EN G I + A D D G NA++TY++ Sbjct: 1999 RTSKKMIGVEISDVNDNAPLFIKPTYDAFLPENNLPGALIYSLHAKDLDVGDNAKVTYSI 2058 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 + + +V +I+ + T LDRET++ ++L++TA DGG+P ++ TA Sbjct: 2059 LNTNTDFSVSSYFSIN-----IETGAPLDRETESIHELVLTAFDGGNPVQTGTAIIKIIV 2113 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSI 414 F Y V L E+ P + ++ ++A D DE ++++ Y + + + Sbjct: 2114 SDFNDNAPIFTQEVYTVSLNENIPVNSTILRVSANDKDEGSNSQITYYFAASSKQAMNTF 2173 Query: 415 TSQNGRGLITVAQPLDF-KQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFEN 471 + G + + LDF K ER + + + A D G S + ++I I D N+ PVF Sbjct: 2174 IIDSISGEVKTKENLDFEKIEREFQIQIMAKDHGSPSLNSSTNLRICIVDFNDNLPVFSQ 2233 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 Y S+ E+ PI +T+L VSA D D GIN+QI Y S+ S++ + + F+IN +G Sbjct: 2234 EVYKVSINENIPINSTILYVSANDKDEGINSQIRYYFST--SSKQILN---TFIINSISG 2288 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 AI T + LD E Y ++V A D + T + I+V D NDN P+F Q++Y +I Sbjct: 2289 AIMTKENLDFEKTKLYEISVQAND-QYTGETGTALIRITVTDANDNFPMFSQEIYKVSIN 2347 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNKALDRESV 650 E+ + ++V V A+D D G+N ++ Y ++ +F I+P SG I T+ LDRE Sbjct: 2348 ENMPLNSTVLYVSASDKDEGINSQLTYSFSSASKQATNAFAINPQSGEIVTSSTLDREMK 2407 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710 + +D+ A D G+PP SS + + + DIND+ PVFE YISEN+ G +I I+ Sbjct: 2408 SHYDITIQATDKGSPPLSSRKTIRLDVSDINDNAPVFEKSTYIVYISENNEPGASIYSIQ 2467 Query: 711 AHDPDEGPNA-VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 A D D NA +V+ SI + N R SD +ELV + L+ E+ +E+V+ A Sbjct: 2468 ASDKDSEENAKLVYSSITSNREEN-----LRIDSDISELVLEIPLNRET-ESIHEIVLTA 2521 Query: 770 ---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR-VPAYDAD--V 823 SP + I VTD+NDN P+ ++ + + P+ V A D D + Sbjct: 2522 FDGGSPMQTGTALIRITVTDMNDNFPIFGQ-EVYTVSINENIPLNSTVLCVSANDKDQGI 2580 Query: 824 TDKLQYRI--LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG---VNEIKA 878 ++ Y S + +N TG + L+ K + V DG V+ K Sbjct: 2581 NSQITYSFSATSKQASRSFSINSETGEIKTKENLDFEKTKNYEISVQAKDGGGLVSHAKI 2640 Query: 879 MMQLSV 884 +Q++V Sbjct: 2641 NIQITV 2646 Score = 356 bits (875), Expect = 6e-96 Identities = 271/886 (30%), Positives = 427/886 (48%), Gaps = 73/886 (8%) Query: 28 YEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQ 87 Y+ SV E A +TV+ L ATD+D G NA++ Y+I + + Sbjct: 733 YKVSVSENAPINSTVIILTATDKDEGTNAKITYSISKTSKNNF----------------- 775 Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 + ID +G L+ LDRE + + + + A D +PV + TA I + + D NDN Sbjct: 776 --YTIDLDNGNLVLENPLDREMQSTHELTLTAFDGGTPVR---TGTALIKITVTDVNDNV 830 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 P F++ Y S+ E+ V N + + ATD D G N+ I Y+ ++ FSID SG Sbjct: 831 PVFTQAVYKASISENSPV--NTTVLYVNATDKDEGINAQIVYSF--SVSEKYFSIDLQSG 886 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 + + K LD E + L++ A DGG+P RS T + I + D NDN P F +++ S+S Sbjct: 887 MLYVKKPLDRETQTIHELILTASDGGNPVRSGTALIRIAVTDSNDNLPVFTQEVYKVSIS 946 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 EN+PI +++ V A D DEG NA++ Y+ + +I+ SG + T + E Sbjct: 947 ENIPINSTVLTVNATDRDEGTNAQIMYSFSKTSGNNLHTSMFSINYTSGEIKTKQNFNFE 1006 Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM-PGQYEVELAEDEPP----- 381 + Y++ V A D G P S A+ + P V+ + + P Sbjct: 1007 AKKFYEISVYAKDYGSPSLSCNASLTIRITDQNDNVPKILYPSSESVDSSFEMVPVASEQ 1066 Query: 382 GTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL 439 G + + A DAD + L Y + G+ FSI SQN G I ++ LD ++ Y + Sbjct: 1067 GALITKVVAVDADSGHNAWLSYHVVQGSEPSLFSI-SQN-TGEIRTSRSLDREKVPWYNI 1124 Query: 440 TVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497 T+ ATD G S+ +++++I+D N+ APVF + Y A + E+ G ++ + A+D D Sbjct: 1125 TIQATDRGSPHLSNIKLIKLDISDVNDNAPVFTKSSYVAYIAENNLAGASIYRIQASDID 1184 Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKLLDRETMSGYLLTVTARDG 556 G NA+++Y + F I+ TG I T+ K LDRET S + L +TA DG Sbjct: 1185 AGDNAKLSYHV-------VQGSEPSLFSISQNTGEIRTSQKPLDRETQSIHELILTASDG 1237 Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616 G P + T + I V D NDN PVF Q++Y +I E+A + +SV + ATD D G N +I Sbjct: 1238 GNPLRTGTALIRIIVTDSNDNLPVFTQEVYKVSISENAPINSSVIILTATDKDEGTNAQI 1297 Query: 617 HYELDPKDREE---GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673 Y + F I+P G I + S + A DGGTP ++ T ++ Sbjct: 1298 TYSISKTSENNFYTSVFNINPVMGEITIK--VSTSSSYYRIITTTASDGGTPVRTGTALI 1355 Query: 674 HIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN 733 + + D ND+ PVF + ISEN+PI +T+ + A D DEG NA + Y Sbjct: 1356 RVIVTDANDNTPVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITY--------- 1406 Query: 734 SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDN 790 SFS T S A+LV LD E + +EL++ A+ +P + ++VTD NDN Sbjct: 1407 SFS-RTSVNSLHAKLVLERPLDREI-KNIHELLLTASDGGTPVRTGTALIRVIVTDANDN 1464 Query: 791 APVMKDFQIIFNNYKDCFPV-GPFGRVPAYDADVTDKLQ----YRILSGN--NANLILLN 843 PV ++ + + P+ RV A D D Q + S N +A++ +N Sbjct: 1465 TPVFTQ-EVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSENSLHASMFSIN 1523 Query: 844 ETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889 T+G + L+ + + ++ +DG ++ L ++T+ Sbjct: 1524 PTSGEIKTKRPLDRETKNIHELLLTASDGGTPVRTGTALIRVIVTD 1569 Score = 255 bits (625), Expect = 1e-65 Identities = 198/648 (30%), Positives = 305/648 (47%), Gaps = 45/648 (6%) Query: 137 HVNII--DDNDNYPQFSEKTYTVSVDEDISVT--DNPVIAKIKAT--DADVGANSAIRYA 190 H II D NDN P F+++ Y V + E S + + +A + T D Sbjct: 18 HTRIIISDANDNIPVFTKEVYKVRITESSSSSLFEMVPLASEQGTLITKDTITLEISEST 77 Query: 191 IIGGNTQMQFSIDSLSGDVSLVK-TLDYEQVRSYRLVIRAQDGGSPS--------RSNTT 241 + G + +Q + D G S+ + L Q S + IR P R T Sbjct: 78 LPGTHLVLQTAEDPDIGINSVQRYILSDNQFLSLKEKIRTDGSKIPELVLEKYLDRETQT 137 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY----TMT 297 + I I D NDN P F +++ +SEN P+ +++ V A D DEG+NA++TY T Sbjct: 138 LIKIIISDANDNIPEFSKEVYKVKMSENTPVNTTVLSVDATDKDEGLNAQITYSFSKTSD 197 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357 ++ +TG D I+P SG + T LD E+ Y++ + A DGG A Sbjct: 198 NQLHTGTFD----INPTSGKITTKRDLDFESVQSYEIAIEAMDGGG--FVAQTKVLIEII 251 Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSIT 415 + ED PGT + + D D + + +I G F I Sbjct: 252 DENDNAPEISIASLSAPIPEDSMPGTVIALIKVHDQDTGRNGEVDCQILGA---APFQIV 308 Query: 416 SQNGRGL-ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENA 472 S + R I A LD ++ Y +T+ ATD G S T ++I ITD N++ P+F Sbjct: 309 SSSSRYYRIITASFLDREKVPWYNITILATDKGSPELSSTKSIKIAITDVNDHIPMFTQE 368 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 Y S+ E PI TTVL V+ATD D G+NAQITYSL S +++A F INP +G Sbjct: 369 VYKVSISESIPINTTVLQVNATDKDEGVNAQITYSL-IRTSGDSLA--SATFSINPASGE 425 Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592 I T + L+ E Y ++V A+D + ++IS DVNDN P+F + Y A + E Sbjct: 426 IKTKRNLNFEVQKHYEMSVEAKDKSY--IKKVIRLDIS--DVNDNPPLFLKSTYVAYLPE 481 Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREE----GSFVIDPASGVIRTNKALDRE 648 + + G S+ ++ A+D D+G N ++ Y + + E+ F I+ +GV+ + ++ D E Sbjct: 482 NNIPGASIYKIQASDLDLGDNAKVIYSISNSNTEDFAVSSFFSINIETGVLYSQRSFDYE 541 Query: 649 SVATHDLKAVAIDGGTPPQS-STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 ++ +A DGG+PP S + + I + D ND+ PVF ISE++PI +T+ Sbjct: 542 QHKVFQMEIMARDGGSPPLSNNATLFMIIVTDYNDNVPVFTQQVYKISISESAPINSTVT 601 Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755 + A D D+G N + YS ++ + E+ T VD D Sbjct: 602 VVTATDKDDGTNGHITYSFSRTAENAFHTQMFNINPANGEIKTKVDAD 649 Score = 250 bits (612), Expect = 4e-64 Identities = 195/661 (29%), Positives = 307/661 (46%), Gaps = 37/661 (5%) Query: 1 MSVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD--IGKNAEV 58 +++ C H +I + D ND+ PVF + Y+ + E +SS + A++Q I K+ Sbjct: 11 LALILCKHTRIIISDANDNIPVFTKEVYKVRITESSSSSLFEMVPLASEQGTLITKDTIT 70 Query: 59 EYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVK 118 E T VQ D + +L + D K+ VL K Sbjct: 71 LEISESTLPGTHLVLQTAEDPDIGINSVQRYILSDNQFLSLKEKIRTDGSKIPE-LVLEK 129 Query: 119 ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178 D+ + I + I D NDN P+FS++ Y V + E+ V N + + ATD Sbjct: 130 YLDR--------ETQTLIKIIISDANDNIPEFSKEVYKVKMSENTPV--NTTVLSVDATD 179 Query: 179 ADVGANSAIRYAII-GGNTQMQ---FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS 234 D G N+ I Y+ + Q+ F I+ SG ++ + LD+E V+SY + I A DGG Sbjct: 180 KDEGLNAQITYSFSKTSDNQLHTGTFDINPTSGKITTKRDLDFESVQSYEIAIEAMDGGG 239 Query: 235 PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294 T++LI I D NDNAP + + E+ G I ++ +D D G N E+ Sbjct: 240 FVAQ--TKVLIEIIDENDNAPEISIASLSAPIPEDSMPGTVIALIKVHDQDTGRNGEV-- 295 Query: 295 TMTDKDYTGNVDLPI-TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353 D G I + R + T+ LDRE Y + + ATD G P S+T + Sbjct: 296 ---DCQILGAAPFQIVSSSSRYYRIITASFLDREKVPWYNITILATDKGSPELSSTKSIK 352 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI--TGGNTR 409 F Y+V ++E P T V+ + ATD DE + ++ Y + T G++ Sbjct: 353 IAITDVNDHIPMFTQEVYKVSISESIPINTTVLQVNATDKDEGVNAQITYSLIRTSGDSL 412 Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVF 469 + + G I + L+F+ ++ Y ++V A D +++++I+D N+ P+F Sbjct: 413 ASATFSINPASGEIKTKRNLNFEVQKHYEMSVEAKDKS--YIKKVIRLDISDVNDNPPLF 470 Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 + Y A + E+ G ++ + A+D D+G NA++ YS+S+ SN F IN + Sbjct: 471 LKSTYVAYLPENNIPGASIYKIQASDLDLGDNAKVIYSISN--SNTEDFAVSSFFSINIE 528 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLS-DTTDVEISVVDVNDNEPVFKQQLYTA 588 TG + + + D E + + + ARDGG P LS + T I V D NDN PVF QQ+Y Sbjct: 529 TGVLYSQRSFDYEQHKVFQMEIMARDGGSPPLSNNATLFMIIVTDYNDNVPVFTQQVYKI 588 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR---EEGSFVIDPASGVIRTNKAL 645 +I E A + ++V+ V ATD D G NG I Y F I+PA+G I+T Sbjct: 589 SISESAPINSTVTVVTATDKDDGTNGHITYSFSRTAENAFHTQMFNINPANGEIKTKVDA 648 Query: 646 D 646 D Sbjct: 649 D 649 Score = 215 bits (525), Expect = 1e-53 Identities = 165/546 (30%), Positives = 260/546 (47%), Gaps = 56/546 (10%) Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325 +SE+ G +V A D D G+N+ Y ++D + + T + + LD Sbjct: 73 ISESTLPGTHLVLQTAEDPDIGINSVQRYILSDNQFLSLKEKIRTDGSKIPELVLEKYLD 132 Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 RETQ +++++ + P F Y+V+++E+ P T V Sbjct: 133 RETQTLIKIIISDANDNIPE--------------------FSKEVYKVKMSENTPVNTTV 172 Query: 386 VTLTATDADE--DNRLHYEI--TGGNT--RGRFSITSQNGRGLITVAQPLDFKQERRYVL 439 +++ ATD DE + ++ Y T N G F I +G+ IT + LDF+ + Y + Sbjct: 173 LSVDATDKDEGLNAQITYSFSKTSDNQLHTGTFDINPTSGK--ITTKRDLDFESVQSYEI 230 Query: 440 TVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499 + A D GG V I I D N+ AP A +A + ED+ GT + ++ D D G Sbjct: 231 AIEAMDGGGFVAQTKVLIEIIDENDNAPEISIASLSAPIPEDSMPGTVIALIKVHDQDTG 290 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 N ++ + + V+ + + I T LDRE + Y +T+ A D G P Sbjct: 291 RNGEVDCQILGAAPFQIVSSSSRYY-------RIITASFLDREKVPWYNITILATDKGSP 343 Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619 LS T ++I++ DVND+ P+F Q++Y +I E + T+V QV ATD D G+N +I Y Sbjct: 344 ELSSTKSIKIAITDVNDHIPMFTQEVYKVSISESIPINTTVLQVNATDKDEGVNAQITYS 403 Query: 620 L---DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676 L +F I+PASG I+T + L+ E +++ A D + ++ + Sbjct: 404 LIRTSGDSLASATFSINPASGEIKTKRNLNFEVQKHYEMSVEAKDKSYIKK----VIRLD 459 Query: 677 IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD----- 731 I D+ND+PP+F Y+ EN+ G +I +I+A D D G NA V YSI + Sbjct: 460 ISDVNDNPPLFLKSTYVAYLPENNIPGASIYKIQASDLDLGDNAKVIYSISNSNTEDFAV 519 Query: 732 SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRV-EILVTDV 787 S+ FS+ G L + DYE K +++ I A SPPL N+ + I+VTD Sbjct: 520 SSFFSINIETG----VLYSQRSFDYEQ-HKVFQMEIMARDGGSPPLSNNATLFMIIVTDY 574 Query: 788 NDNAPV 793 NDN PV Sbjct: 575 NDNVPV 580 Score = 204 bits (498), Expect = 3e-50 Identities = 145/438 (33%), Positives = 218/438 (49%), Gaps = 29/438 (6%) Query: 449 RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508 R +++I I+DAN+ P F Y + E+ P+ TTVL V ATD D G+NAQITYS Sbjct: 133 RETQTLIKIIISDANDNIPEFSKEVYKVKMSENTPVNTTVLSVDATDKDEGLNAQITYSF 192 Query: 509 SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568 S N+ H F INP +G ITT + LD E++ Y + + A DGG T V Sbjct: 193 SKTSDNQL---HTGTFDINPTSGKITTKRDLDFESVQSYEIAIEAMDGG--GFVAQTKVL 247 Query: 569 ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG 628 I ++D NDN P +A I ED++ GT ++ + D D G NG E+D + Sbjct: 248 IEIIDENDNAPEISIASLSAPIPEDSMPGTVIALIKVHDQDTGRNG----EVDCQILGAA 303 Query: 629 SF-VIDPASGVIR--TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685 F ++ +S R T LDRE V +++ +A D G+P SST + I I D+ND P Sbjct: 304 PFQIVSSSSRYYRIITASFLDREKVPWYNITILATDKGSPELSSTKSIKIAITDVNDHIP 363 Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI--KGGDD--SNSFSLETRQ 741 +F + ISE+ PI TT+ ++ A D DEG NA + YS+ GD S +FS+ Sbjct: 364 MFTQEVYKVSISESIPINTTVLQVNATDKDEGVNAQITYSLIRTSGDSLASATFSINPAS 423 Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801 G E+ T +L++E +K YE+ + A V + + ++DVNDN P+ + Sbjct: 424 G----EIKTKRNLNFE-VQKHYEMSVEAKDKSYIKKV-IRLDISDVNDNPPLFLKSTYVA 477 Query: 802 NNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGNN-----ANLILLNETTGSMTLSPQ 854 ++ P ++ A D D+ D K+ Y I + N ++ +N TG + Sbjct: 478 YLPENNIPGASIYKIQASDLDLGDNAKVIYSISNSNTEDFAVSSFFSINIETGVLYSQRS 537 Query: 855 LNTNVPKLATMEVSVTDG 872 + K+ ME+ DG Sbjct: 538 FDYEQHKVFQMEIMARDG 555 >UniRef50_O15943 Cluster: Neural-cadherin precursor; n=42; Arthropoda|Rep: Neural-cadherin precursor - Drosophila melanogaster (Fruit fly) Length = 3097 Score = 409 bits (1006), Expect = e-112 Identities = 434/1687 (25%), Positives = 697/1687 (41%), Gaps = 178/1687 (10%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTADTLNPE 73 D ND P+F ++ E +V EG GT V + A D+D N +V Y I D+ E Sbjct: 1291 DVNDEIPLFTEREQE-TVLEGEPIGTKVTQVNAIDKDGTFPNNQVYYYI----VDSPRNE 1345 Query: 74 DAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD---QASPVSDRL 130 ++ F I+ +SG + T+ DREK Y + V+A D A P S+ Sbjct: 1346 G------------KEFFEINLQSGEIFTKTVFDREKKGAYALEVEARDGAPSARPNSNGP 1393 Query: 131 SS-TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 +S T I + I D NDN P F + Y VDE+ + + + A D D +S IRY Sbjct: 1394 NSVTKFIRIGIADKNDNPPYFDKSLYEAEVDENEDIQHT--VLTVTAKDHD--ESSRIRY 1449 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I GN F++ +++G + + LDYE R Y L + A D + N T ++I+++D Sbjct: 1450 EITSGNIGGAFAVKNMTGAIYVAGALDYETRRRYELRLAASDN---LKENYTTVIIHVKD 1506 Query: 250 VNDNAPRFYTSLFQESVSE----NVPIGYSIVRVQAYDADEGVNAELTYTMTDK--DYTG 303 VNDN P F ++ ++E N+P +++V A D D+ + Y +T + D Sbjct: 1507 VNDNPPVFERPTYRTQITEEDDRNLP--KRVLQVTATDGDKDRPQNIVYFLTGQGIDPDN 1564 Query: 304 NVDLPITIDPRSGWVYTSGQLDRET---QAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 + I+ +G ++ LDR+ + +++ V A D G A Sbjct: 1565 PANSKFDINRTTGEIFVLKPLDRDQPNGRPQWRFTVFAQDEGGEGLVGYADVQVNLKDIN 1624 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN-----RLHYEITGG---NTRGRF 412 F G Y + E+ G V+T+TA D D+ N RL Y I G Sbjct: 1625 DNAPIFPQGVYFGNVTENGTAGMVVMTMTAVDYDDPNEGSNARLVYSIEKNVIEEETGSP 1684 Query: 413 SITSQNGRGLI-TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN 471 + G+I T LD ++ Y + V A D GG T I + D N+ P F Sbjct: 1685 IFEIEPDTGVIKTAVCCLDRERTPDYSIQVVAMDGGGLKGTGTASIRVKDINDMPPQFTK 1744 Query: 472 APYTASVFE-DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ- 529 + V E D + +++ T D + Y + I N V N Sbjct: 1745 DEWFTEVDETDGTALPEMPILTVTVHDEDETNKFQYKV---IDNSGYGADKFTMVRNNDG 1801 Query: 530 TGAITTNKLLDRETM---SGYLLTVTARDGGVPSLSDTTDVEISVV-----DVNDNEPVF 581 TG++ + LD E +G+ + D G + +D V S V D+NDN+P F Sbjct: 1802 TGSLKIVQPLDYEDQLQSNGFRFRIQVNDKGEDNDNDKYHVAYSWVVVKLRDINDNKPHF 1861 Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641 ++ ++ ED VGT + + ATD D G ++ Y +D + F I+ +G + Sbjct: 1862 ERANVEVSVFEDTKVGTELEKFKATDPDQGGKSKVSYSIDRSSDRQRQFAINQ-NGSVTI 1920 Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701 ++LDRE V H +K +AID G+PP+++T + + ++DIND+ P F D + E+ P Sbjct: 1921 QRSLDREVVPRHQVKILAIDDGSPPKTATATLTVIVQDINDNAPKFLKDYRP-VLPEHVP 1979 Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIK---GGDD--SNSFSLETRQ----GSDKAELVTMV 752 + + D D + + + DD SF +E Q G A + ++ Sbjct: 1980 PRKVVEILATDDDDRSKSNGPPFQFRLDPSADDIIRASFKVEQDQKGANGDGMAVISSLR 2039 Query: 753 DLDYESPRKKY--ELVIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809 D E +K+Y +VI+ SP + + +++ DVNDN I NY+ P Sbjct: 2040 SFDREQ-QKEYMIPIVIKDHGSPAMTGTSTLTVIIGDVNDNKMQPGSKDIFVYNYQGQSP 2098 Query: 810 VGPFGRVPAYDADVTDKLQYRIL-SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVS 868 P GRV YD D D + L+E +G +T+ L Sbjct: 2099 DTPIGRVYVYDLDDWDLPDKKFYWEAMEHPRFKLDEDSGMVTMRAGTREGRYHLRFKVYD 2158 Query: 869 VTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFL-----------SPLLGFFI 917 +I A + ++VR I E ++NS +VRL+ ++ E F+ + F Sbjct: 2159 RKHTQTDIPANVTVTVREIPHEAVVNSGSVRLSGISDEDFIRVWNYRTQSMSRSKMDRFR 2218 Query: 918 DGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRE 977 D LA ++ +EN+ IFSVQ P +V + SP+Y P L Sbjct: 2219 DKLADLLNTERENVDIFSVQ------------LKRKHPPLTDVRFSAHGSPYYKPVRLNG 2266 Query: 978 RVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIY 1037 V +HR + + + + + C++E + C L+ VN++ + Sbjct: 2267 IVLMHREEIEKDVGINITMVGIDECLYENQMCEGSCTNSLEISPLPYMVNANKTALVGVR 2326 Query: 1038 PVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAA 1097 T C C SC + C +G +CV R G CS Sbjct: 2327 VDTIADCTC-------GARNFTKPESCRT----TPCHNGGRCVDTRFG----PHCSCPVG 2371 Query: 1098 YTTAVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRY--NERHDFL 1155 YT C+ RSF + + +P L+ HL L+F T+ GL++YNG ER + L Sbjct: 2372 YTGPRCQQTTRSFRGNGWAWYPPLEMCDESHLSLEFITRKPDGLIIYNGPIVPPERDETL 2431 Query: 1156 ALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDC 1215 + ++ E R G P L F G + + + + DG WH +++ + +I M++D C Sbjct: 2432 ISDFIALELER-GYPRLLIDFGSGTLELRVKTKKTLDDGEWHRIDLFWDTESIRMVVDFC 2490 Query: 1216 DKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGL--PNIPSS 1273 K +A D G F AR +IP + +L++ PLQ+GGL S Sbjct: 2491 -KSAEIAEMED-GTP---PEFDDMSCQARGQIP--PFNEYLNVNAPLQVGGLYREQFDQS 2543 Query: 1274 -----FQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRC----SSAPCYN 1324 + K F GCI + + K DL ++AGCP+ C ++A C+ Sbjct: 2544 LYFWHYMPTAKGFDGCIRNLVHNSKLYDLAHPGLSRNSVAGCPQTEEVCAQTETTARCWE 2603 Query: 1325 GAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLRPIQLPWLNALSIR 1384 C C C+ G TG C T P F + + P + L R Sbjct: 2604 HGNCVGSLSEARCHCRPGWTGPACNIPT-IPTTFKAQSYVKYALSFEPDRFSTQVQLRFR 2662 Query: 1385 TRQR--DAFVMS---------IQLKSGLLHYSYN-------GETMYLPMATLSDGAWHRI 1426 TR+ + F +S +++K G LH+ YN + ++L ++DG WH + Sbjct: 2663 TREEYGELFRVSDQHNREYGILEIKDGHLHFRYNLNSLRTEEKDLWLNAIVVNDGQWHVV 2722 Query: 1427 EIKWLGTDISVTVDYGL-RTVLMPMLANKIQGQYIGK---ILIGGLDTTAGLLASDV--G 1480 ++ G+ ++ +D G R Q + K + GG G+ +V Sbjct: 2723 KVNRYGSAATLELDGGEGRRYNETFEFVGHQWLLVDKQEGVYAGGKAEYTGVRTFEVYAD 2782 Query: 1481 FFEGCIQDVRIGTAQSLL---------NRPTVRENVRDGCQSRADCMLSICPPYSKCVTS 1531 + + C+ D+R+ L + T+ N+ GC S C ICP +CV Sbjct: 2783 YQKSCLDDIRLEGKHLPLPPAMNGTQWGQATMARNLEKGCPSNKPCSNVICPDPFECVDL 2842 Query: 1532 WDSSTCTCEAGRV-GPQ---CV--SACELGPC-GAARCVPDQTPKGYSCACEPGYTLTTS 1584 W+ CTC GR+ P C+ + C PC A C+ + Y C C G+ Sbjct: 2843 WNVYECTCGEGRIMSPDSKGCMDRNECLDMPCMNGATCINLEPRLRYRCICPDGFWGENC 2902 Query: 1585 GCIESGK 1591 ++ G+ Sbjct: 2903 ELVQEGQ 2909 Score = 339 bits (834), Expect = 5e-91 Identities = 255/741 (34%), Positives = 377/741 (50%), Gaps = 64/741 (8%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR-LSSTATIHVNIIDDNDNYP 148 F +D RSG + TR + + Y + VKA DQ V DR ST ++I+ P Sbjct: 591 FEVDERSGVVRTRGTDLFQLDMEYVLYVKAEDQNGKVDDRRFQSTPEERLSIVGGK-RAP 649 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG-GNTQMQFSIDSLSG 207 QF +Y + E+ D+ +I+ IKA A+ IRY + G F+I SG Sbjct: 650 QFYMPSYEAEIPEN-QKKDSDIIS-IKAKSF---ADREIRYTLKAQGQGAGTFNIGPTSG 704 Query: 208 DVSLVKTLDYEQVRS---YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ- 263 V L K LD+E +R Y L++ A + S S + L I + DVNDNAP+F +Q Sbjct: 705 IVKLAKELDFEDLRQPHVYSLIVTATED-SGGFSTSVDLTIRVTDVNDNAPKFELPDYQA 763 Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323 +V E++P+G SI+RV+A D+D G NAE+ Y ++D + VD +G + + Q Sbjct: 764 HNVDEDIPLGTSILRVKAMDSDSGSNAEIEYLVSDDHFA--VD-------SNGIIVNNKQ 814 Query: 324 LDRETQ-AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382 LD + A Y+ +VTA D G+PP+S AT F Y + E+ P Sbjct: 815 LDADNNNAYYEFIVTAKDKGEPPKSGVATVRVYTKNKNDEEPKFSQQVYTPNVDENAGPN 874 Query: 383 TPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 T V T+ A+D D DN + GG + G+F I ++ G+I + + +Y L V+ Sbjct: 875 TLVTTVVASDKDGDNVRFGFVGGGTSSGQFVI--EDITGVIRLHNKAISLDKDKYELNVT 932 Query: 443 ATDSGG---------RSDTAMVQINITDANNYAPVFEN-APYTASVFEDAPIGTTVLVVS 492 A D G + TA+V + ITD N+ PVF++ + Y V E AP G+ V+ V Sbjct: 933 AMDDGSCCVNGDQTIHTSTAVVVVFITDVNDNKPVFKDCSTYYPKVEEGAPNGSPVIKVV 992 Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552 ATD D G+N Q+ YS+ + + + +F ++ +TG ++TNK+ DRE G ++VT Sbjct: 993 ATDEDKGVNGQVKYSIVQQPNQKGT-----KFTVDEETGEVSTNKVFDREGDDGKFVSVT 1047 Query: 553 --ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610 A D G PSL + + DVNDN P+F +Q Y N+ +DA +GT++ +V A+D D Sbjct: 1048 VKATDQGDPSLEGVCSFTVEITDVNDNPPLFDRQKYVENVKQDASIGTNILRVSASDEDA 1107 Query: 611 GLNGRIHYEL----DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 NG I Y L +P D E F I SG I K LDRE T+ L+A+A D G PP Sbjct: 1108 DNNGAIVYSLTAPFNPNDLE--YFEIQAESGWIVLKKPLDRE---TYKLEAMAQDKGYPP 1162 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCL-TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 S TV V I + D ++PPV++ Y+ EN P+G + I+A EG N V Y Sbjct: 1163 LSRTVEVQIDVVDRANNPPVWDHTVYGPIYVKENMPVGGKVVSIKASSGIEG-NPTVFYR 1221 Query: 726 IKGGDDS-----NSFSLETR--QGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLW 775 + G + ++F L+ R G A++ LDYES K+Y L IR + L Sbjct: 1222 LMPGSTAQTNKFHTFYLQQRPDNGDTWADIKVNHPLDYES-IKEYNLTIRVENNGAQQLA 1280 Query: 776 NDVRVEILVTDVNDNAPVMKD 796 ++ V I++ DVND P+ + Sbjct: 1281 SEATVYIMLEDVNDEIPLFTE 1301 Score = 309 bits (759), Expect = 6e-82 Identities = 269/927 (29%), Positives = 428/927 (46%), Gaps = 91/927 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND+ P+F+ Q+Y +V++ AS GT +L + A+D+D N + Y++ TA Sbjct: 1066 VEITDVNDNPPLFDRQKYVENVKQDASIGTNILRVSASDEDADNNGAIVYSL---TA-PF 1121 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 NP D + F I SG ++ + LDRE Y + A D+ P L Sbjct: 1122 NPNDL------------EYFEIQAESGWIVLKKPLDRE---TYKLEAMAQDKGYP---PL 1163 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTY-TVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S T + ++++D +N P + Y + V E++ V + IKA+ + + N + Y Sbjct: 1164 SRTVEVQIDVVDRANNPPVWDHTVYGPIYVKENMPVGGK--VVSIKAS-SGIEGNPTVFY 1220 Query: 190 AIIGGNT-----------QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238 ++ G+T Q + D+ + LDYE ++ Y L IR ++ G+ + Sbjct: 1221 RLMPGSTAQTNKFHTFYLQQRPDNGDTWADIKVNHPLDYESIKEYNLTIRVENNGAQQLA 1280 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV-NAELTYTMT 297 + + I + DVND P F T QE+V E PIG + +V A D D N ++ Y + Sbjct: 1281 SEATVYIMLEDVNDEIPLF-TEREQETVLEGEPIGTKVTQVNAIDKDGTFPNNQVYYYIV 1339 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG-------GDPPRSATA 350 D + I+ +SG ++T DRE + Y L V A DG + P S T Sbjct: 1340 DSPRNEGKEF-FEINLQSGEIFTKTVFDREKKGAYALEVEARDGAPSARPNSNGPNSVTK 1398 Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG 410 F YE E+ E+E V+T+TA D DE +R+ YEIT GN G Sbjct: 1399 FIRIGIADKNDNPPYFDKSLYEAEVDENEDIQHTVLTVTAKDHDESSRIRYEITSGNIGG 1458 Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFE 470 F++ +N G I VA LD++ RRY L ++A+D+ + T ++ I++ D N+ PVFE Sbjct: 1459 AFAV--KNMTGAIYVAGALDYETRRRYELRLAASDNLKENYTTVI-IHVKDVNDNPPVFE 1515 Query: 471 NAPYTASVFE--DAPIGTTVLVVSATDSDVGINAQITYSLSSE-ISNEAVAHHDQQFVIN 527 Y + E D + VL V+ATD D I Y L+ + I + A + +F IN Sbjct: 1516 RPTYRTQITEEDDRNLPKRVLQVTATDGDKDRPQNIVYFLTGQGIDPDNPA--NSKFDIN 1573 Query: 528 PQTGAITTNKLLDRETMSG---YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584 TG I K LDR+ +G + TV A+D G L DV++++ D+NDN P+F Q Sbjct: 1574 RTTGEIFVLKPLDRDQPNGRPQWRFTVFAQDEGGEGLVGYADVQVNLKDINDNAPIFPQG 1633 Query: 585 LYTANIMEDALVGTSVSQVGATDAD---VGLNGRIHYELDPK--DREEGS--FVIDPASG 637 +Y N+ E+ G V + A D D G N R+ Y ++ + E GS F I+P +G Sbjct: 1634 VYFGNVTENGTAGMVVMTMTAVDYDDPNEGSNARLVYSIEKNVIEEETGSPIFEIEPDTG 1693 Query: 638 VIRTNK-ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696 VI+T LDRE + ++ VA+DGG + T I+++DIND PP F D ++ Sbjct: 1694 VIKTAVCCLDRERTPDYSIQVVAMDGGGLKGTGT--ASIRVKDINDMPPQFTKD--EWFT 1749 Query: 697 SENSPIGTTIGE-----IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751 + GT + E + HD DE G ++ F++ R L + Sbjct: 1750 EVDETDGTALPEMPILTVTVHDEDETNKFQYKVIDNSGYGADKFTM-VRNNDGTGSLKIV 1808 Query: 752 VDLDYESPRK----KYELVIRAASPPLWNDVR------VEILVTDVNDNAPVMKDFQIIF 801 LDYE + ++ + + ND V + + D+NDN P + + Sbjct: 1809 QPLDYEDQLQSNGFRFRIQVNDKGEDNDNDKYHVAYSWVVVKLRDINDNKPHFERANVEV 1868 Query: 802 NNYKDCFPVGPFGRVPAYDADV--TDKLQYRI-LSGNNANLILLNETTGSMTLSPQLNTN 858 + ++D + A D D K+ Y I S + +N+ GS+T+ L+ Sbjct: 1869 SVFEDTKVGTELEKFKATDPDQGGKSKVSYSIDRSSDRQRQFAINQ-NGSVTIQRSLDRE 1927 Query: 859 -VPKLATMEVSVTDGVNEIKAMMQLSV 884 VP+ +++ DG A L+V Sbjct: 1928 VVPRHQVKILAIDDGSPPKTATATLTV 1954 Score = 291 bits (713), Expect = 2e-76 Identities = 251/820 (30%), Positives = 380/820 (46%), Gaps = 83/820 (10%) Query: 11 INVLDCNDHSPVFEMQQYEA-SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 I V D ND++P FE+ Y+A +V E GT++L +KA D D G NAE+EY + Sbjct: 744 IRVTDVNDNAPKFELPDYQAHNVDEDIPLGTSILRVKAMDSDSGSNAEIEYLVS------ 797 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDRE-KVARYTVLVKATDQASPVSD 128 D F +D +G ++ LD + A Y +V A D+ P Sbjct: 798 -----------------DDHFAVDS-NGIIVNNKQLDADNNNAYYEFIVTAKDKGEPPK- 838 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 S AT+ V + ND P+FS++ YT +VDE+ N ++ + A+D D G N +R Sbjct: 839 --SGVATVRVYTKNKNDEEPKFSQQVYTPNVDENAG--PNTLVTTVVASDKD-GDN--VR 891 Query: 189 YAIIGGNTQM-QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS-------PSRSNT 240 + +GG T QF I+ ++G + L Y L + A D GS ++T Sbjct: 892 FGFVGGGTSSGQFVIEDITGVIRLHNKAISLDKDKYELNVTAMDDGSCCVNGDQTIHTST 951 Query: 241 TQLLINIRDVNDNAPRFY-TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 +++ I DVNDN P F S + V E P G +++V A D D+GVN ++ Y++ + Sbjct: 952 AVVVVFITDVNDNKPVFKDCSTYYPKVEEGAPNGSPVIKVVATDEDKGVNGQVKYSIVQQ 1011 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRE-TQAKY-QLLVTATDGGDPPRSATATXXXXXX 357 T+D +G V T+ DRE K+ + V ATD GDP + Sbjct: 1012 --PNQKGTKFTVDEETGEVSTNKVFDREGDDGKFVSVTVKATDQGDPSLEGVCSFTVEIT 1069 Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEIT---GGNTRGRF 412 F +Y + +D GT ++ ++A+D D DN + Y +T N F Sbjct: 1070 DVNDNPPLFDRQKYVENVKQDASIGTNILRVSASDEDADNNGAIVYSLTAPFNPNDLEYF 1129 Query: 413 SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFE 470 I +++ G I + +PLD Y L A D G S T VQI++ D N PV++ Sbjct: 1130 EIQAES--GWIVLKKPLD---RETYKLEAMAQDKGYPPLSRTVEVQIDVVDRANNPPVWD 1184 Query: 471 NAPY-TASVFEDAPIGTTVLVVSATDSDVGINAQITYSL---SSEISNEAVAHHDQQFVI 526 + Y V E+ P+G V+ + A+ G N + Y L S+ +N+ + QQ Sbjct: 1185 HTVYGPIYVKENMPVGGKVVSIKASSGIEG-NPTVFYRLMPGSTAQTNKFHTFYLQQRPD 1243 Query: 527 NPQTGA-ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585 N T A I N LD E++ Y LT+ + G L+ V I + DVND P+F ++ Sbjct: 1244 NGDTWADIKVNHPLDYESIKEYNLTIRVENNGAQQLASEATVYIMLEDVNDEIPLFTER- 1302 Query: 586 YTANIMEDALVGTSVSQVGATDADVGL-NGRIHYELDPKDREEGS--FVIDPASGVIRTN 642 ++E +GT V+QV A D D N +++Y + R EG F I+ SG I T Sbjct: 1303 EQETVLEGEPIGTKVTQVNAIDKDGTFPNNQVYYYIVDSPRNEGKEFFEINLQSGEIFTK 1362 Query: 643 KALDRESVATHDLKAVAIDG-------GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695 DRE + L+ A DG P S T + I I D ND+PP F+ Sbjct: 1363 TVFDREKKGAYALEVEARDGAPSARPNSNGPNSVTKFIRIGIADKNDNPPYFDKSLYEAE 1422 Query: 696 ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755 + EN I T+ + A D DE ++ + Y I G+ +F+++ G+ + LD Sbjct: 1423 VDENEDIQHTVLTVTAKDHDE--SSRIRYEITSGNIGGAFAVKNMTGA----IYVAGALD 1476 Query: 756 YESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMK 795 YE+ R++YEL + A+ N V I V DVNDN PV + Sbjct: 1477 YET-RRRYELRLAASDNLKENYTTVIIHVKDVNDNPPVFE 1515 Score = 236 bits (578), Expect = 6e-60 Identities = 203/750 (27%), Positives = 333/750 (44%), Gaps = 81/750 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I + D ND+ P F+ YEA V E TVLT+ A D D +++ + Y I Sbjct: 1401 RIGIADKNDNPPYFDKSLYEAEVDENEDIQHTVLTVTAKDHD--ESSRIRYEI------- 1451 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + F + +GA+ +LD E RY + + A+D Sbjct: 1452 ------------TSGNIGGAFAVKNMTGAIYVAGALDYETRRRYELRLAASDNLK----- 1494 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + T+ +++ D NDN P F TY + E+ + ++ ATD D I Y Sbjct: 1495 -ENYTTVIIHVKDVNDNPPVFERPTYRTQITEEDDRNLPKRVLQVTATDGDKDRPQNIVY 1553 Query: 190 AIIG------GNTQMQFSIDSLSGDVSLVKTLDYEQVR---SYRLVIRAQDGGSPSRSNT 240 + G +F I+ +G++ ++K LD +Q +R + AQD G Sbjct: 1554 FLTGQGIDPDNPANSKFDINRTTGEIFVLKPLDRDQPNGRPQWRFTVFAQDEGGEGLVGY 1613 Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD---EGVNAELTYTMT 297 + +N++D+NDNAP F ++ +V+EN G ++ + A D D EG NA L Y++ Sbjct: 1614 ADVQVNLKDINDNAPIFPQGVYFGNVTENGTAGMVVMTMTAVDYDDPNEGSNARLVYSIE 1673 Query: 298 DKDYTGNVDLPI-TIDPRSGWVYTS-GQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355 PI I+P +G + T+ LDRE Y + V A DGG T T Sbjct: 1674 KNVIEEETGSPIFEIEPDTGVIKTAVCCLDRERTPDYSIQVVAMDGGG--LKGTGTASIR 1731 Query: 356 XXXXXXXXXXFMPGQYEVELAEDEP---PGTPVVTLTATDADEDNRLHYEITGGNTRG-- 410 F ++ E+ E + P P++T+T D DE N+ Y++ + G Sbjct: 1732 VKDINDMPPQFTKDEWFTEVDETDGTALPEMPILTVTVHDEDETNKFQYKVIDNSGYGAD 1791 Query: 411 RFSITSQN-GRGLITVAQPLDFK---QERRYVLTVSATDSGGRSDT-------AMVQINI 459 +F++ N G G + + QPLD++ Q + + D G +D + V + + Sbjct: 1792 KFTMVRNNDGTGSLKIVQPLDYEDQLQSNGFRFRIQVNDKGEDNDNDKYHVAYSWVVVKL 1851 Query: 460 TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAH 519 D N+ P FE A SVFED +GT + ATD D G ++++YS+ + + Sbjct: 1852 RDINDNKPHFERANVEVSVFEDTKVGTELEKFKATDPDQGGKSKVSYSI------DRSSD 1905 Query: 520 HDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP 579 +QF IN Q G++T + LDRE + + + + A D G P + T + + V D+NDN P Sbjct: 1906 RQRQFAIN-QNGSVTIQRSLDREVVPRHQVKILAIDDGSPPKTATATLTVIVQDINDNAP 1964 Query: 580 VFKQQLYTANIMEDALVGTSVSQVGATDAD--VGLNG-RIHYELDPK--DREEGSFVIDP 634 F + ++ + + V ++ ATD D NG + LDP D SF ++ Sbjct: 1965 KFLKDY--RPVLPEHVPPRKVVEILATDDDDRSKSNGPPFQFRLDPSADDIIRASFKVEQ 2022 Query: 635 ----ASG----VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686 A+G VI + ++ DRE + + V D G+P + T + + I D+ND+ Sbjct: 2023 DQKGANGDGMAVISSLRSFDREQQKEYMIPIVIKDHGSPAMTGTSTLTVIIGDVNDNKMQ 2082 Query: 687 FESDCLTFYISENSPIGTTIGEIRAHDPDE 716 S + Y + T IG + +D D+ Sbjct: 2083 PGSKDIFVYNYQGQSPDTPIGRVYVYDLDD 2112 Score = 219 bits (536), Expect = 7e-55 Identities = 209/697 (29%), Positives = 316/697 (45%), Gaps = 65/697 (9%) Query: 206 SGDVSLVKTLDYEQVRSYR------LVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259 +G V + K DYE++ + ++ ++ +++I ++DVND P F Sbjct: 486 NGAVRVKKKWDYEELGPEKTIDFWVIITNMGHNAGIKYTDNQRVIILVKDVNDEPPYFIN 545 Query: 260 S--LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317 Q V N P + +QA D D N + Y + +D TG +D RSG Sbjct: 546 RPLPMQAVVQLNAPPNTPVFTLQARDPDTDHN--IHYFIV-RDRTGG---RFEVDERSGV 599 Query: 318 VYTSGQLDRETQAKYQLLVTATDGG---DPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374 V T G + +Y L V A D D R + F YE E Sbjct: 600 VRTRGTDLFQLDMEYVLYVKAEDQNGKVDDRRFQSTPEERLSIVGGKRAPQFYMPSYEAE 659 Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITG-GNTRGRFSITSQNGRGLITVAQPLDFKQ 433 + E++ + ++++ A + D + Y + G G F+I + G++ +A+ LDF+ Sbjct: 660 IPENQKKDSDIISIKA-KSFADREIRYTLKAQGQGAGTFNIGPTS--GIVKLAKELDFED 716 Query: 434 ERR---YVLTVSAT-DSGGRSDTAMVQINITDANNYAPVFENAPYTA-SVFEDAPIGTTV 488 R+ Y L V+AT DSGG S + + I +TD N+ AP FE Y A +V ED P+GT++ Sbjct: 717 LRQPHVYSLIVTATEDSGGFSTSVDLTIRVTDVNDNAPKFELPDYQAHNVDEDIPLGTSI 776 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 L V A DSD G NA+I Y +S D F ++ G I NK LD + + Y Sbjct: 777 LRVKAMDSDSGSNAEIEYLVS-----------DDHFAVD-SNGIIVNNKQLDADNNNAYY 824 Query: 549 -LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 VTA+D G P S V + + ND EP F QQ+YT N+ E+A T V+ V A+D Sbjct: 825 EFIVTAKDKGEPPKSGVATVRVYTKNKNDEEPKFSQQVYTPNVDENAGPNTLVTTVVASD 884 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT-NKA--LDRE----SVATHDLKAVAI 660 D + + G FVI+ +GVIR NKA LD++ +V D + + Sbjct: 885 KD---GDNVRFGFVGGGTSSGQFVIEDITGVIRLHNKAISLDKDKYELNVTAMDDGSCCV 941 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY--ISENSPIGTTIGEIRAHDPDEGP 718 +G +ST +V + I D+ND+ PVF+ DC T+Y + E +P G+ + ++ A D D+G Sbjct: 942 NGDQTIHTSTAVVVVFITDVNDNKPVFK-DCSTYYPKVEEGAPNGSPVIKVVATDEDKGV 1000 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY-ELVIRA---ASPPL 774 N V YSI N + + E+ T D E K+ + ++A P L Sbjct: 1001 NGQVKYSIV--QQPNQKGTKFTVDEETGEVSTNKVFDREGDDGKFVSVTVKATDQGDPSL 1058 Query: 775 WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPA--YDADVTDKLQYRI 831 + +TDVNDN P+ D Q N K +G RV A DAD + Y + Sbjct: 1059 EGVCSFTVEITDVNDNPPLF-DRQKYVENVKQDASIGTNILRVSASDEDADNNGAIVYSL 1117 Query: 832 LSGNNAN---LILLNETTGSMTLSPQLNTNVPKLATM 865 + N N + +G + L L+ KL M Sbjct: 1118 TAPFNPNDLEYFEIQAESGWIVLKKPLDRETYKLEAM 1154 Score = 193 bits (470), Expect = 7e-47 Identities = 201/759 (26%), Positives = 321/759 (42%), Gaps = 56/759 (7%) Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS 164 L EK + V++ T+ + + + + + D ND P F + + ++ Sbjct: 500 LGPEKTIDFWVII--TNMGHNAGIKYTDNQRVIILVKDVNDEPPYFINRPLPMQAVVQLN 557 Query: 165 VTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR 224 N + ++A D D N I Y I+ T +F +D SG V T ++ Y Sbjct: 558 APPNTPVFTLQARDPDTDHN--IHYFIVRDRTGGRFEVDERSGVVRTRGTDLFQLDMEYV 615 Query: 225 LVIRAQD--GGSPSR--SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQ 280 L ++A+D G R +T + ++I AP+FY ++ + EN I+ ++ Sbjct: 616 LYVKAEDQNGKVDDRRFQSTPEERLSIVG-GKRAPQFYMPSYEAEIPENQKKDSDIISIK 674 Query: 281 AYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK---YQLLVT 337 A + E+ YT+ + G I P SG V + +LD E + Y L+VT Sbjct: 675 ---AKSFADREIRYTLKAQ---GQGAGTFNIGPTSGIVKLAKELDFEDLRQPHVYSLIVT 728 Query: 338 ATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN 397 AT+ ++ +P + ED P GT ++ + A D+D + Sbjct: 729 ATEDSGGFSTSVDLTIRVTDVNDNAPKFELPDYQAHNVDEDIPLGTSILRVKAMDSDSGS 788 Query: 398 RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYV-LTVSATDSG--GRSDTAM 454 E + F++ S G+I + LD Y V+A D G +S A Sbjct: 789 NAEIEYLVSD--DHFAVDS---NGIIVNNKQLDADNNNAYYEFIVTAKDKGEPPKSGVAT 843 Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 V++ + N+ P F YT +V E+A T V V A+D D G N + + S Sbjct: 844 VRVYTKNKNDEEPKFSQQVYTPNVDENAGPNTLVTTVVASDKD-GDNVRFGFVGGGTSSG 902 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL-------SDTTDV 567 QFVI TG I + Y L VTA D G + + T V Sbjct: 903 --------QFVIEDITGVIRLHNKAISLDKDKYELNVTAMDDGSCCVNGDQTIHTSTAVV 954 Query: 568 EISVVDVNDNEPVFKQ-QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE 626 + + DVNDN+PVFK Y + E A G+ V +V ATD D G+NG++ Y + + + Sbjct: 955 VVFITDVNDNKPVFKDCSTYYPKVEEGAPNGSPVIKVVATDEDKGVNGQVKYSIVQQPNQ 1014 Query: 627 EGS-FVIDPASGVIRTNKALDRESVATH--DLKAVAIDGGTPPQSSTVIVHIKIEDINDS 683 +G+ F +D +G + TNK DRE + A D G P ++I D+ND+ Sbjct: 1015 KGTKFTVDEETGEVSTNKVFDREGDDGKFVSVTVKATDQGDPSLEGVCSFTVEITDVNDN 1074 Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 PP+F+ + +++ IGT I + A D D N + YS+ + N Q + Sbjct: 1075 PPLFDRQKYVENVKQDASIGTNILRVSASDEDADNNGAIVYSLTAPFNPNDLEYFEIQ-A 1133 Query: 744 DKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN 803 + +V LD E+ K + PPL V V+I V D +N PV D + Sbjct: 1134 ESGWIVLKKPLDRET-YKLEAMAQDKGYPPLSRTVEVQIDVVDRANNPPVW-DHTVYGPI 1191 Query: 804 Y-KDCFPVGPFGRVPAYDA----DVTDKLQYRILSGNNA 837 Y K+ PVG G+V + A + + YR++ G+ A Sbjct: 1192 YVKENMPVG--GKVVSIKASSGIEGNPTVFYRLMPGSTA 1228 Score = 161 bits (391), Expect = 3e-37 Identities = 155/533 (29%), Positives = 239/533 (44%), Gaps = 56/533 (10%) Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 +P Q V+L + PP TPV TL A D D D+ +HY I T GRF + ++ G++ Sbjct: 548 LPMQAVVQL--NAPPNTPVFTLQARDPDTDHNIHYFIVRDRTGGRFEVDERS--GVVRTR 603 Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITD-----ANNYAPVFENAPYTASVFED 481 F+ + YVL V A D G+ D Q + AP F Y A + E+ Sbjct: 604 GTDLFQLDMEYVLYVKAEDQNGKVDDRRFQSTPEERLSIVGGKRAPQFYMPSYEAEIPEN 663 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 + ++ + A + +I Y+L ++ F I P +G + K LD Sbjct: 664 QKKDSDIISIKAKSF---ADREIRYTLKAQGQGAGT------FNIGPTSGIVKLAKELDF 714 Query: 542 ETMSG---YLLTVTA-RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA-NIMEDALV 596 E + Y L VTA D G S + D+ I V DVNDN P F+ Y A N+ ED + Sbjct: 715 EDLRQPHVYSLIVTATEDSG--GFSTSVDLTIRVTDVNDNAPKFELPDYQAHNVDEDIPL 772 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE-SVATHDL 655 GTS+ +V A D+D G N I Y + + F +D ++G+I NK LD + + A ++ Sbjct: 773 GTSILRVKAMDSDSGSNAEIEYLV-----SDDHFAVD-SNGIIVNNKQLDADNNNAYYEF 826 Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 A D G PP+S V + ++ ND P F T + EN+ T + + A D D Sbjct: 827 IVTAKDKGEPPKSGVATVRVYTKNKNDEEPKFSQQVYTPNVDENAGPNTLVTTVVASDKD 886 Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASP 772 G N + + GG S F +E D ++ + + + KYEL + A S Sbjct: 887 -GDNVRFGF-VGGGTSSGQFVIE-----DITGVIRLHNKAISLDKDKYELNVTAMDDGSC 939 Query: 773 PLWNDVRVE-------ILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD-- 822 + D + + +TDVNDN PV KD + ++ P G P +V A D D Sbjct: 940 CVNGDQTIHTSTAVVVVFITDVNDNKPVFKDCSTYYPKVEEGAPNGSPVIKVVATDEDKG 999 Query: 823 VTDKLQYRILSGNN--ANLILLNETTGSMTLSPQLNT--NVPKLATMEVSVTD 871 V +++Y I+ N ++E TG ++ + + + K ++ V TD Sbjct: 1000 VNGQVKYSIVQQPNQKGTKFTVDEETGEVSTNKVFDREGDDGKFVSVTVKATD 1052 Score = 68.1 bits (159), Expect = 3e-09 Identities = 91/370 (24%), Positives = 158/370 (42%), Gaps = 38/370 (10%) Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT-AMVQINITDANNYAPVFENAPYT 475 ++G L+T +PLD ++ Y L+V A+D G T + +QI + D N+ P+F++ Y Sbjct: 253 ESGVWLVT-NRPLDREERAHYDLSVEASDVDGLDRTVSKIQITVLDENDNRPIFKSLDYK 311 Query: 476 ASVF--EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 ++ + A + + V + +G + T + +I+ + +I PQTG I Sbjct: 312 FAIAGQKSASMESNSSVTYQRFAIMG-KVEATDADGDKIAYR-LKSPSNVVIIVPQTGEI 369 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV--FKQQLYTANI- 590 L T + L+ V A D PSL ++ +++ EPV Q L +I Sbjct: 370 ---MLAGEPTSNELLIEVIAHDLRYPSLVSAKPAKV-LLEFLAAEPVSFIMQHLEHDDIN 425 Query: 591 -----MEDALVGTSV---SQVGATDADVGLNGRIHYELDP-------KDREEGSFVIDPA 635 E V +V ++ T+AD G+ ++L+ K R++ +V Sbjct: 426 NHSHHREKRRVTRAVRPTKRIEFTEADGDTEGKSVFQLEKETDKETFKIRDDNPWVTVET 485 Query: 636 SGVIRTNKALDRESVA---THDLKAVAIDGGTP---PQSSTVIVHIKIEDINDSPPVFES 689 +G +R K D E + T D + + G + V I ++D+ND PP F + Sbjct: 486 NGAVRVKKKWDYEELGPEKTIDFWVIITNMGHNAGIKYTDNQRVIILVKDVNDEPPYFIN 545 Query: 690 DCLTF--YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747 L + N+P T + ++A DPD N +HY I F ++ R G + Sbjct: 546 RPLPMQAVVQLNAPPNTPVFTLQARDPDTDHN--IHYFIVRDRTGGRFEVDERSGVVRTR 603 Query: 748 LVTMVDLDYE 757 + LD E Sbjct: 604 GTDLFQLDME 613 Score = 46.0 bits (104), Expect = 0.015 Identities = 42/145 (28%), Positives = 67/145 (46%), Gaps = 18/145 (12%) Query: 49 DQDIGKNAEVEYTI-ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGA-LLTRASLD 106 D+++ +V YTI + D ++ V D SG L+T LD Sbjct: 206 DEELATPKKVRYTIIDGNVDDAFALQERKANKNIQISAKSLVINGDDESGVWLVTNRPLD 265 Query: 107 REKVARYTVLVKATDQASPVSDRLSSTAT-IHVNIIDDNDNYPQFSEKTY--------TV 157 RE+ A Y + V+A+D D L T + I + ++D+NDN P F Y + Sbjct: 266 REERAHYDLSVEASDV-----DGLDRTVSKIQITVLDENDNRPIFKSLDYKFAIAGQKSA 320 Query: 158 SVDEDISVTDN--PVIAKIKATDAD 180 S++ + SVT ++ K++ATDAD Sbjct: 321 SMESNSSVTYQRFAIMGKVEATDAD 345 Score = 45.6 bits (103), Expect = 0.020 Identities = 31/90 (34%), Positives = 48/90 (53%), Gaps = 6/90 (6%) Query: 501 NAQITYSLSSEISNEAVAHHDQQFVIN--PQTGA-ITTNKLLDRETMSGYLLTVTARDGG 557 N ++L +N+ + + VIN ++G + TN+ LDRE + Y L+V A D Sbjct: 223 NVDDAFALQERKANKNIQISAKSLVINGDDESGVWLVTNRPLDREERAHYDLSVEASD-- 280 Query: 558 VPSLSDTTD-VEISVVDVNDNEPVFKQQLY 586 V L T ++I+V+D NDN P+FK Y Sbjct: 281 VDGLDRTVSKIQITVLDENDNRPIFKSLDY 310 >UniRef50_UPI00006A0F32 Cluster: dachsous 2 isoform 1; n=1; Xenopus tropicalis|Rep: dachsous 2 isoform 1 - Xenopus tropicalis Length = 2474 Score = 407 bits (1001), Expect = e-111 Identities = 303/918 (33%), Positives = 455/918 (49%), Gaps = 73/918 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++++ D ND+ PVF Y A + E G+++ ++A D D G NA+V Y+I Sbjct: 1199 KLDLSDVNDNPPVFSKPTYVAYLPENNLPGSSIYRIQAFDFDSGNNAKVVYSI------- 1251 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 LN V F I+ SG L + S D E+ +++ + A D SP Sbjct: 1252 LN-------TYIQDIPVSAYFSINVVSGVLYAQRSFDYEQHQMFSMEITARDSGSPP--- 1301 Query: 130 LSSTATIHVNIIDDNDNYPQF---SEKTYTVSVDEDISVTDNP--VIAKIKATDADVGAN 184 L+S T+ + IID NDN P+ S S+ E + + +I K+ A DAD G N Sbjct: 1302 LNSNITLIIYIIDQNDNAPEILYPSPNGGGSSLFEMVPLASEQGSLITKVIAVDADSGHN 1361 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDV-SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 S + Y I + FSI+ +G++ + K LD E ++ ++L++ A DGG+P R+ T + Sbjct: 1362 SWLSYHFIPMSDPSPFSINQYTGEIRTCQKPLDRENLKIHKLLLTAFDGGNPVRTGTALI 1421 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 I I DVND+ P F +++ S+SE++PI ++++V A D DEGVNA++TY++ Sbjct: 1422 RIAITDVNDHIPMFTQEVYKVSISESIPINTTVLQVNATDKDEGVNAQITYSLIRTSGDS 1481 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVT----ATDGGDPPRSATATXXXXXXXX 359 +I+P SG + T L+ E Q Y++ V ATDGG+P R+ TA Sbjct: 1482 LASATFSINPASGEIKTKRNLNFEVQKHYEMSVEAKDGATDGGNPKRTGTALLRIIVTDY 1541 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGR------FS 413 F Y++ ++E P + V +TATD D+ H + T F+ Sbjct: 1542 NDNVPVFTQQVYKISISESAPINSTVTVVTATDKDDGTNGHITYSFSRTAENAFHTQMFN 1601 Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFE 470 I NG V+ + E V +T GG R+ TA+++I +TD+N+ PVF Sbjct: 1602 INPANGEIKTKVS---NINTEDFPVSPYFSTSDGGNPLRTGTALIRIIVTDSNDNLPVFT 1658 Query: 471 NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 Y SV E+API +TV++++ATD D G NA+ITYS+S N + F INP T Sbjct: 1659 QEVYKVSVSENAPINSTVIILTATDKDEGTNAKITYSISKTSKNN---FYTSIFHINPAT 1715 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590 G ITT + L+ E Y ++V A DGG L + V I + DVNDN PVF Q +Y A+I Sbjct: 1716 GEITTKENLNFENKEHYEMSVQAEDGG--GLVAQSKVLIEITDVNDNVPVFTQAVYKASI 1773 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG---VIRTNKALDR 647 E++ V T+V V ATD D G+N +I Y E SF +D ++G I T ALDR Sbjct: 1774 SENSPVNTTVLYVNATDKDEGINAQIVYSF--SKTSENSFHLDSSTGRFYRIVTKSALDR 1831 Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 E A +++ VA D G+P SS + + I D+ND+PPVF Y+ EN+ G++I Sbjct: 1832 EKTALYNITIVATDKGSPQLSSRKFIRLDISDVNDNPPVFMKSKDVAYLPENNLPGSSIY 1891 Query: 708 EIRAHDPDEGPNAVVHYSIKGGDD-----SNSFSLETRQGSDKAELVTMVDLDYESPRKK 762 I+A D D G NA V YSI D+ S+ FS+ G L DYE K+ Sbjct: 1892 RIQASDLDTGDNAKVIYSISSMDNEDFPISSYFSINIETG----VLYAQRSFDYEQV-KE 1946 Query: 763 YELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPA 818 +++ I A+ +P + I VTD NDN PV ++ + + P+ V A Sbjct: 1947 FQIQITASDGGNPVRSGTALIRIAVTDANDNLPVFTQ-EVYKVSISENIPINSTVLTVNA 2005 Query: 819 YDADVTDKLQYRILSGNNANLILLNETTGS-------MTLSPQLNTNVPKLATMEVSVTD 871 D D Q LS N LNE T S + L L+ + + ++ +D Sbjct: 2006 TDRDEGTNAQSYRLSDN--QYFRLNEKTNSDLSKTPELVLEKPLDRETQSIHELILTASD 2063 Query: 872 GVNEIKAMMQLSVRLITE 889 G N ++ L ++T+ Sbjct: 2064 GGNPLRTGTALIRIIVTD 2081 Score = 380 bits (936), Expect = e-103 Identities = 250/750 (33%), Positives = 399/750 (53%), Gaps = 55/750 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D ND+ PVF Y+AS+ E + TTVL + ATD+D G NA++ Y+ + ++ Sbjct: 1752 IEITDVNDNVPVFTQAVYKASISENSPVNTTVLYVNATDKDEGINAQIVYSFSKTSENSF 1811 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + + + GR ++T+++LDREK A Y + + ATD+ SP +L Sbjct: 1812 HLDSST-----------------GRFYRIVTKSALDREKTALYNITIVATDKGSP---QL 1851 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SS I ++I D NDN P F + + E+ + I +I+A+D D G N+ + Y+ Sbjct: 1852 SSRKFIRLDISDVNDNPPVFMKSKDVAYLPENNLPGSS--IYRIQASDLDTGDNAKVIYS 1909 Query: 191 IIGGNTQ-----MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 I + + FSI+ +G + ++ DYEQV+ +++ I A DGG+P RS T + I Sbjct: 1910 ISSMDNEDFPISSYFSINIETGVLYAQRSFDYEQVKEFQIQITASDGGNPVRSGTALIRI 1969 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 + D NDN P F +++ S+SEN+PI +++ V A D DEG NA+ +Y ++D Y Sbjct: 1970 AVTDANDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQ-SYRLSDNQYFRLN 2028 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 + + ++ + LDRETQ+ ++L++TA+DGG+P R+ TA Sbjct: 2029 EKTNSDLSKTPELVLEKPLDRETQSIHELILTASDGGNPLRTGTALIRIIVTDSNDNLPV 2088 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRF-SITSQNG--- 419 F Y+V ++E+ P + V+ LTATD DE ++ Y I+ + + S+ + N Sbjct: 2089 FTQEVYKVSISENAPINSSVIILTATDKDEGTNAQITYSISKTSENNFYTSVFNINPVIY 2148 Query: 420 ----RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAP 473 + + +PLD + ++ + L ++A+D G ++ TA+++I +TDAN+ PVF A Sbjct: 2149 YKIVNTELMLEKPLDRETQKDHELILTASDGGDPVKTGTAIIRIIVTDANDNLPVFTKAV 2208 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYS-LSSEISNEAVAHHDQQFVINPQTGA 532 Y S+ E+ PI ++VL V+ATD D G NAQITYS + + +S+ F IN +TG Sbjct: 2209 YKVSISENIPINSSVLHVNATDRDEGTNAQITYSFIKTSVSS--------YFSINIETGV 2260 Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP-VFKQQLYTANIM 591 + + D E + + V A+D G PSLS + I ++D NDN P + +I Sbjct: 2261 LYAQRSFDYEQHKEFAMHVQAKDNGYPSLSSNATLIIRIIDQNDNAPKILYPSTENMSIS 2320 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDP---KDREEGSFVIDPASGVIRTNKALDRE 648 E+ + ++V +V A+D D G N +I Y F I+P SG I+TN L+ E Sbjct: 2321 ENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEIKTNNLLNYE 2380 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 ++ +++ A DGG S ++V +I D+ND+PPVF T Y+ EN+ G TI Sbjct: 2381 AIRDYEISVQAKDGGGFVAHSKILV--EITDVNDNPPVFIKSAYTIYLPENNLPGATIYR 2438 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738 I A D D G NA V YSI + S LE Sbjct: 2439 IHALDLDMGDNAKVIYSIYVSEKYFSVDLE 2468 Score = 375 bits (923), Expect = e-102 Identities = 267/836 (31%), Positives = 409/836 (48%), Gaps = 51/836 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I V D ND+ PVF + Y+ SV E A +TV+ L ATD+D G NA++ Y+I + + Sbjct: 1644 RIIVTDSNDNLPVFTQEVYKVSVSENAPINSTVIILTATDKDEGTNAKITYSISKTSKNN 1703 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 +F I+ +G + T+ +L+ E Y + V+A D V+ Sbjct: 1704 F---------------YTSIFHINPATGEITTKENLNFENKEHYEMSVQAEDGGGLVAQ- 1747 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + + + I D NDN P F++ Y S+ E+ V N + + ATD D G N+ I Y Sbjct: 1748 ----SKVLIEITDVNDNVPVFTQAVYKASISENSPV--NTTVLYVNATDKDEGINAQIVY 1801 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 + ++ F +DS +G + T LD E+ Y + I A D GSP S+ + ++ Sbjct: 1802 SF-SKTSENSFHLDSSTGRFYRIVTKSALDREKTALYNITIVATDKGSPQLSSRKFIRLD 1860 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 I DVNDN P F S + EN G SI R+QA D D G NA++ Y+++ D N D Sbjct: 1861 ISDVNDNPPVFMKSKDVAYLPENNLPGSSIYRIQASDLDTGDNAKVIYSISSMD---NED 1917 Query: 307 LPIT----IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 PI+ I+ +G +Y D E ++Q+ +TA+DGG+P RS TA Sbjct: 1918 FPISSYFSINIETGVLYAQRSFDYEQVKEFQIQITASDGGNPVRSGTALIRIAVTDANDN 1977 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422 F Y+V ++E+ P + V+T+ ATD DE N R + + + Sbjct: 1978 LPVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQSYRLSDNQYFRLNEKTNSDLSK 2037 Query: 423 ---ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTAS 477 + + +PLD + + + L ++A+D G R+ TA+++I +TD+N+ PVF Y S Sbjct: 2038 TPELVLEKPLDRETQSIHELILTASDGGNPLRTGTALIRIIVTDSNDNLPVFTQEVYKVS 2097 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ------TG 531 + E+API ++V++++ATD D G NAQITYS+S N + F INP Sbjct: 2098 ISENAPINSSVIILTATDKDEGTNAQITYSISKTSENN---FYTSVFNINPVIYYKIVNT 2154 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 + K LDRET + L +TA DGG P + T + I V D NDN PVF + +Y +I Sbjct: 2155 ELMLEKPLDRETQKDHELILTASDGGDPVKTGTAIIRIIVTDANDNLPVFTKAVYKVSIS 2214 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA 651 E+ + +SV V ATD D G N +I Y K F I+ +GV+ ++ D E Sbjct: 2215 ENIPINSSVLHVNATDRDEGTNAQITYSFI-KTSVSSYFSINIETGVLYAQRSFDYEQHK 2273 Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP-VFESDCLTFYISENSPIGTTIGEIR 710 + A D G P SS + I+I D ND+ P + ISEN+PI +T+ + Sbjct: 2274 EFAMHVQAKDNGYPSLSSNATLIIRIIDQNDNAPKILYPSTENMSISENTPINSTVLRVN 2333 Query: 711 AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770 A D DEG NA + YS ++ + E+ T L+YE+ R YE+ ++A Sbjct: 2334 ASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEIKTNNLLNYEAIRD-YEISVQAK 2392 Query: 771 SPPLW-NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD 825 + ++ + +TDVNDN PV ++ P R+ A D D+ D Sbjct: 2393 DGGGFVAHSKILVEITDVNDNPPVFIKSAYTIYLPENNLPGATIYRIHALDLDMGD 2448 Score = 369 bits (909), Expect = e-100 Identities = 273/894 (30%), Positives = 436/894 (48%), Gaps = 65/894 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I V D ND+ PVF Q Y+ S+ E A +TV + ATD+D G N + Y+ + Sbjct: 1535 RIIVTDYNDNVPVFTQQVYKISISESAPINSTVTVVTATDKDDGTNGHITYSFSRTAENA 1594 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + + +F I+ +G + T+ S + + +D +P+ Sbjct: 1595 FHTQ---------------MFNINPANGEIKTKVSNINTEDFPVSPYFSTSDGGNPLR-- 1637 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + TA I + + D NDN P F+++ Y VSV E+ + +I + ATD D G N+ I Y Sbjct: 1638 -TGTALIRIIVTDSNDNLPVFTQEVYKVSVSENAPINSTVII--LTATDKDEGTNAKITY 1694 Query: 190 AIIGGNTQ----MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 +I + F I+ +G+++ + L++E Y + ++A+DGG + ++LI Sbjct: 1695 SISKTSKNNFYTSIFHINPATGEITTKENLNFENKEHYEMSVQAEDGGGLVAQS--KVLI 1752 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 I DVNDN P F ++++ S+SEN P+ +++ V A D DEG+NA++ Y+ + K + Sbjct: 1753 EITDVNDNVPVFTQAVYKASISENSPVNTTVLYVNATDKDEGINAQIVYSFS-KTSENSF 1811 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 L + R + T LDRE A Y + + ATD G P S+ Sbjct: 1812 HLDSSTG-RFYRIVTKSALDREKTALYNITIVATDKGSPQLSSRKFIRLDISDVNDNPPV 1870 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRGRFSITSQNG---- 419 FM + L E+ PG+ + + A+D D DN ++ Y I+ + F I+S Sbjct: 1871 FMKSKDVAYLPENNLPGSSIYRIQASDLDTGDNAKVIYSISSMDNED-FPISSYFSINIE 1929 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTAS 477 G++ + D++Q + + + ++A+D G RS TA+++I +TDAN+ PVF Y S Sbjct: 1930 TGVLYAQRSFDYEQVKEFQIQITASDGGNPVRSGTALIRIAVTDANDNLPVFTQEVYKVS 1989 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 + E+ PI +TVL V+ATD D G NAQ +Y LS N+ +++ +T + K Sbjct: 1990 ISENIPINSTVLTVNATDRDEGTNAQ-SYRLSD---NQYFRLNEKTNSDLSKTPELVLEK 2045 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LDRET S + L +TA DGG P + T + I V D NDN PVF Q++Y +I E+A + Sbjct: 2046 PLDRETQSIHELILTASDGGNPLRTGTALIRIIVTDSNDNLPVFTQEVYKVSISENAPIN 2105 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREE---GSFVIDPAS--GVIRTN----KALDRE 648 +SV + ATD D G N +I Y + F I+P ++ T K LDRE Sbjct: 2106 SSVIILTATDKDEGTNAQITYSISKTSENNFYTSVFNINPVIYYKIVNTELMLEKPLDRE 2165 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 + H+L A DGG P ++ T I+ I + D ND+ PVF ISEN PI +++ Sbjct: 2166 TQKDHELILTASDGGDPVKTGTAIIRIIVTDANDNLPVFTKAVYKVSISENIPINSSVLH 2225 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768 + A D DEG NA + YS S+ FS+ G L DYE K++ + ++ Sbjct: 2226 VNATDRDEGTNAQITYSFIKTSVSSYFSINIETGV----LYAQRSFDYEQ-HKEFAMHVQ 2280 Query: 769 AAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDAD-- 822 A P L ++ + I + D NDNAP + + + P+ RV A D D Sbjct: 2281 AKDNGYPSLSSNATLIIRIIDQNDNAPKILYPSTENMSISENTPINSTVLRVNASDMDEG 2340 Query: 823 ----VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 +T ++ +A++ +N T+G + + LN + + V DG Sbjct: 2341 TNAQITYSFSRTSVNSLHASMFSINPTSGEIKTNNLLNYEAIRDYEISVQAKDG 2394 Score = 361 bits (888), Expect = 2e-97 Identities = 267/910 (29%), Positives = 434/910 (47%), Gaps = 59/910 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I + D NDH P+F + Y+ S+ E TTVL + ATD+D G NA++ Y++ + D+ Sbjct: 1422 RIAITDVNDHIPMFTQEVYKVSISESIPINTTVLQVNATDKDEGVNAQITYSLIRTSGDS 1481 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD- 128 L F I+ SG + T+ +L+ E Y + V+A D A+ + Sbjct: 1482 L---------------ASATFSINPASGEIKTKRNLNFEVQKHYEMSVEAKDGATDGGNP 1526 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 + + TA + + + D NDN P F+++ Y +S+ E + N + + ATD D G N I Sbjct: 1527 KRTGTALLRIIVTDYNDNVPVFTQQVYKISISESAPI--NSTVTVVTATDKDDGTNGHIT 1584 Query: 189 YAII-----GGNTQMQFSIDSLSGD----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239 Y+ +TQM F+I+ +G+ VS + T D+ V Y DGG+P R+ Sbjct: 1585 YSFSRTAENAFHTQM-FNINPANGEIKTKVSNINTEDFP-VSPY---FSTSDGGNPLRTG 1639 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 T + I + D NDN P F +++ SVSEN PI +++ + A D DEG NA++TY+++ Sbjct: 1640 TALIRIIVTDSNDNLPVFTQEVYKVSVSENAPINSTVIILTATDKDEGTNAKITYSISKT 1699 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 I+P +G + T L+ E + Y++ V A DGG A + Sbjct: 1700 SKNNFYTSIFHINPATGEITTKENLNFENKEHYEMSVQAEDGGG--LVAQSKVLIEITDV 1757 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT-RGRFSITSQN 418 F Y+ ++E+ P T V+ + ATD DE + T F + S Sbjct: 1758 NDNVPVFTQAVYKASISENSPVNTTVLYVNATDKDEGINAQIVYSFSKTSENSFHLDSST 1817 Query: 419 GRGL-ITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYT 475 GR I LD ++ Y +T+ ATD G S ++++I+D N+ PVF + Sbjct: 1818 GRFYRIVTKSALDREKTALYNITIVATDKGSPQLSSRKFIRLDISDVNDNPPVFMKSKDV 1877 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 A + E+ G+++ + A+D D G NA++ YS+SS + NE F IN +TG + Sbjct: 1878 AYLPENNLPGSSIYRIQASDLDTGDNAKVIYSISS-MDNEDFPI-SSYFSINIETGVLYA 1935 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 + D E + + + +TA DGG P S T + I+V D NDN PVF Q++Y +I E+ Sbjct: 1936 QRSFDYEQVKEFQIQITASDGGNPVRSGTALIRIAVTDANDNLPVFTQEVYKVSISENIP 1995 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKD----REEGSFVIDPASGVIRTNKALDRESVA 651 + ++V V ATD D G N + Y L E+ + + ++ K LDRE+ + Sbjct: 1996 INSTVLTVNATDRDEGTNAQ-SYRLSDNQYFRLNEKTNSDLSKTPELV-LEKPLDRETQS 2053 Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711 H+L A DGG P ++ T ++ I + D ND+ PVF + ISEN+PI +++ + A Sbjct: 2054 IHELILTASDGGNPLRTGTALIRIIVTDSNDNLPVFTQEVYKVSISENAPINSSVIILTA 2113 Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP-----RKKYELV 766 D DEG NA + YSI ++N ++ + +L E P +K +EL+ Sbjct: 2114 TDKDEGTNAQITYSISKTSENNFYTSVFNINPVIYYKIVNTELMLEKPLDRETQKDHELI 2173 Query: 767 IRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPAYDAD 822 + A+ P + I+VTD NDN PV + + + P+ V A D D Sbjct: 2174 LTASDGGDPVKTGTAIIRIIVTDANDNLPVFTK-AVYKVSISENIPINSSVLHVNATDRD 2232 Query: 823 --VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAM 879 ++ Y + + ++ +N TG + + K M V D G + + Sbjct: 2233 EGTNAQITYSFIKTSVSSYFSINIETGVLYAQRSFDYEQHKEFAMHVQAKDNGYPSLSSN 2292 Query: 880 MQLSVRLITE 889 L +R+I + Sbjct: 2293 ATLIIRIIDQ 2302 Score = 327 bits (804), Expect = 2e-87 Identities = 271/908 (29%), Positives = 425/908 (46%), Gaps = 82/908 (9%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 H ++N+ D ND++P+F+ Y A + E G+++ + A D D G NA++ Y+I A Sbjct: 873 HIRLNISDVNDNAPIFKKSTYVAYLSENNLPGSSIYRINAYDPDTGDNAKIIYSI----A 928 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 T N +D + F I+ +G L + S D E + + + A D SP Sbjct: 929 GT-NIKD---------IAISSYFSINIETGVLYAQRSFDYEHDKEFQIGITARDHGSP-- 976 Query: 128 DRLSSTATIHVNIIDD--NDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 LSS T+ ++IID NDN P+FS++ Y V + E+ V N + + ATD D G N+ Sbjct: 977 -SLSSNTTLVIHIIDHDANDNIPEFSKEVYKVKMSENTPV--NTTVLSVDATDKDEGLNA 1033 Query: 186 AIRYAII-GGNTQMQ---FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 I Y+ + Q+ F I+ SG ++ + LD+E V+SY + I A DGG T Sbjct: 1034 QITYSFSKTSDNQLHTGTFDINPTSGKITTKRDLDFESVQSYEIAIEAMDGGGFVAQ--T 1091 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 ++LI I D NDNAP + + E+ G I ++ +D D G N E+ D Sbjct: 1092 KVLIEIIDENDNAPEISIASLSAPIPEDSMPGTVIALIKVHDQDTGRNGEV-----DCQI 1146 Query: 302 TGNVDLPI-TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 G I + R + T+ LDRE Y + + ATD G P S+T + Sbjct: 1147 LGAAPFQIVSSSSRYYRIITASFLDREKVPWYNITILATDKGSPELSSTKSIKLDLSDVN 1206 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT-------RGRFS 413 F Y L E+ PG+ + + A D D N + NT FS Sbjct: 1207 DNPPVFSKPTYVAYLPENNLPGSSIYRIQAFDFDSGNNAKVVYSILNTYIQDIPVSAYFS 1266 Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAP-VF 469 I + G++ + D++Q + + + ++A DSG S+ ++ I I D N+ AP + Sbjct: 1267 INVVS--GVLYAQRSFDYEQHQMFSMEITARDSGSPPLNSNITLI-IYIIDQNDNAPEIL 1323 Query: 470 ENAPY--TASVFEDAPI----GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523 +P +S+FE P+ G+ + V A D+D G N+ ++Y +S+ + Sbjct: 1324 YPSPNGGGSSLFEMVPLASEQGSLITKVIAVDADSGHNSWLSYHF-IPMSDPS------P 1376 Query: 524 FVINPQTGAI-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582 F IN TG I T K LDRE + + L +TA DGG P + T + I++ DVND+ P+F Sbjct: 1377 FSINQYTGEIRTCQKPLDRENLKIHKLLLTAFDGGNPVRTGTALIRIAITDVNDHIPMFT 1436 Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL---DPKDREEGSFVIDPASGVI 639 Q++Y +I E + T+V QV ATD D G+N +I Y L +F I+PASG I Sbjct: 1437 QEVYKVSISESIPINTTVLQVNATDKDEGVNAQITYSLIRTSGDSLASATFSINPASGEI 1496 Query: 640 RTNKALDRESVATHDL----KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695 +T + L+ E +++ K A DGG P ++ T ++ I + D ND+ PVF Sbjct: 1497 KTKRNLNFEVQKHYEMSVEAKDGATDGGNPKRTGTALLRIIVTDYNDNVPVFTQQVYKIS 1556 Query: 696 ISENSPIGTTIGEIRAHDPDEGPNAVVHYSI----KGGDDSNSFSLETRQGSDKAELVTM 751 ISE++PI +T+ + A D D+G N + YS + + F++ G K ++ + Sbjct: 1557 ISESAPINSTVTVVTATDKDDGTNGHITYSFSRTAENAFHTQMFNINPANGEIKTKVSNI 1616 Query: 752 VDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811 D+ P Y +P + I+VTD NDN PV ++ + + P+ Sbjct: 1617 NTEDF--PVSPYFSTSDGGNPLRTGTALIRIIVTDSNDNLPVFTQ-EVYKVSVSENAPIN 1673 Query: 812 PFGRV-PAYDAD--VTDKLQYRI--LSGNN--ANLILLNETTGSMTLSPQLNTNVPKLAT 864 + A D D K+ Y I S NN ++ +N TG +T LN + Sbjct: 1674 STVIILTATDKDEGTNAKITYSISKTSKNNFYTSIFHINPATGEITTKENLNFENKEHYE 1733 Query: 865 MEVSVTDG 872 M V DG Sbjct: 1734 MSVQAEDG 1741 Score = 320 bits (785), Expect = 5e-85 Identities = 267/934 (28%), Positives = 431/934 (46%), Gaps = 89/934 (9%) Query: 12 NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT-----IELVT 66 +V D ND+ P+F + Y S+ E G+ + + A+D+D GKNA++ Y +E ++ Sbjct: 608 SVDDINDNPPLFTEELYFFSIAENILPGSLIFQVSASDKDSGKNAQLLYALLESYVEGMS 667 Query: 67 AD---TLNPE--------------DAXXXXXXXXXXVQD------VFRIDGRSGA----L 99 ++NP+ DA D +F +D SG L Sbjct: 668 VSHFISINPDSGNVGHLVTKLRAVDADAGYNAWLTYEMDPVSNTTLFSVDSYSGENTYKL 727 Query: 100 LTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKT----Y 155 +T LDREK + Y + V TD +P LS+ T++V + D NDN P F + T Y Sbjct: 728 VTVGKLDREKSSSYNITVTVTDSGTPP---LSTQKTLYVEVSDLNDNPPTFEKCTNKEVY 784 Query: 156 TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG-GNTQMQ---FSIDSLSGDVSL 211 V + E+ + N + ++ ATD D G NS I Y+ + Q+ F I+ +G++ Sbjct: 785 KVRISENSPI--NSTVIRVNATDKDEGLNSQITYSFSKTSDNQLYTSIFDINPTNGEIRT 842 Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271 LD E Y + I + D GSP S + +NI DVNDNAP F S + +SEN Sbjct: 843 TSFLDRENTSQYNITILSTDRGSPKLSTVKHIRLNISDVNDNAPIFKKSTYVAYLSENNL 902 Query: 272 IGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NVDLPITIDPRSGWVYTSGQLDRETQA 330 G SI R+ AYD D G NA++ Y++ + + +I+ +G +Y D E Sbjct: 903 PGSSIYRINAYDPDTGDNAKIIYSIAGTNIKDIAISSYFSINIETGVLYAQRSFDYEHDK 962 Query: 331 KYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX--XFMPGQYEVELAEDEPPGTPVVTL 388 ++Q+ +TA D G P S+ T F Y+V+++E+ P T V+++ Sbjct: 963 EFQIGITARDHGSPSLSSNTTLVIHIIDHDANDNIPEFSKEVYKVKMSENTPVNTTVLSV 1022 Query: 389 TATDADE--DNRLHYEI--TGGNT--RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 ATD DE + ++ Y T N G F I +G+ IT + LDF+ + Y + + Sbjct: 1023 DATDKDEGLNAQITYSFSKTSDNQLHTGTFDINPTSGK--ITTKRDLDFESVQSYEIAIE 1080 Query: 443 ATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502 A D GG V I I D N+ AP A +A + ED+ GT + ++ D D G N Sbjct: 1081 AMDGGGFVAQTKVLIEIIDENDNAPEISIASLSAPIPEDSMPGTVIALIKVHDQDTGRNG 1140 Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 ++ + + V+ + + I T LDRE + Y +T+ A D G P LS Sbjct: 1141 EVDCQILGAAPFQIVSSSSRYY-------RIITASFLDREKVPWYNITILATDKGSPELS 1193 Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE-LD 621 T +++ + DVNDN PVF + Y A + E+ L G+S+ ++ A D D G N ++ Y L+ Sbjct: 1194 STKSIKLDLSDVNDNPPVFSKPTYVAYLPENNLPGSSIYRIQAFDFDSGNNAKVVYSILN 1253 Query: 622 PKDRE---EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678 ++ F I+ SGV+ ++ D E ++ A D G+PP +S + + I I Sbjct: 1254 TYIQDIPVSAYFSINVVSGVLYAQRSFDYEQHQMFSMEITARDSGSPPLNSNITLIIYII 1313 Query: 679 DINDSPP--VFES-----DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD 731 D ND+ P ++ S L + S G+ I ++ A D D G N+ + Y D Sbjct: 1314 DQNDNAPEILYPSPNGGGSSLFEMVPLASEQGSLITKVIAVDADSGHNSWLSYHFIPMSD 1373 Query: 732 SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVN 788 + FS+ G + LD E+ K ++L++ A +P + I +TDVN Sbjct: 1374 PSPFSINQYTGEIR---TCQKPLDREN-LKIHKLLLTAFDGGNPVRTGTALIRIAITDVN 1429 Query: 789 DNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRIL--SGNN--ANLIL 841 D+ P+ ++ + + P+ +V A D D V ++ Y ++ SG++ + Sbjct: 1430 DHIPMFTQ-EVYKVSISESIPINTTVLQVNATDKDEGVNAQITYSLIRTSGDSLASATFS 1488 Query: 842 LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE 875 +N +G + LN V K M V DG + Sbjct: 1489 INPASGEIKTKRNLNFEVQKHYEMSVEAKDGATD 1522 Score = 315 bits (773), Expect = 1e-83 Identities = 237/785 (30%), Positives = 375/785 (47%), Gaps = 57/785 (7%) Query: 145 DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS 204 ++Y + ++ +S++ D S ++ K++A DAD G N+ + Y + + FS+DS Sbjct: 660 ESYVEGMSVSHFISINPD-SGNVGHLVTKLRAVDADAGYNAWLTYEMDPVSNTTLFSVDS 718 Query: 205 LSGD----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF--- 257 SG+ + V LD E+ SY + + D G+P S L + + D+NDN P F Sbjct: 719 YSGENTYKLVTVGKLDREKSSSYNITVTVTDSGTPPLSTQKTLYVEVSDLNDNPPTFEKC 778 Query: 258 -YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316 +++ +SEN PI +++RV A D DEG+N+++TY+ + I+P +G Sbjct: 779 TNKEVYKVRISENSPINSTVIRVNATDKDEGLNSQITYSFSKTSDNQLYTSIFDINPTNG 838 Query: 317 WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376 + T+ LDRE ++Y + + +TD G P S F Y L+ Sbjct: 839 EIRTTSFLDRENTSQYNITILSTDRGSPKLSTVKHIRLNISDVNDNAPIFKKSTYVAYLS 898 Query: 377 EDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTR-----GRFSITSQNGRGLITVAQPL 429 E+ PG+ + + A D D DN ++ Y I G N + FSI + G++ + Sbjct: 899 ENNLPGSSIYRINAYDPDTGDNAKIIYSIAGTNIKDIAISSYFSINIET--GVLYAQRSF 956 Query: 430 DFKQERRYVLTVSATDSGGRS----DTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 D++ ++ + + ++A D G S T ++ I DAN+ P F Y + E+ P+ Sbjct: 957 DYEHDKEFQIGITARDHGSPSLSSNTTLVIHIIDHDANDNIPEFSKEVYKVKMSENTPVN 1016 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 TTVL V ATD D G+NAQITYS S N+ H F INP +G ITT + LD E++ Sbjct: 1017 TTVLSVDATDKDEGLNAQITYSFSKTSDNQL---HTGTFDINPTSGKITTKRDLDFESVQ 1073 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 Y + + A DGG T V I ++D NDN P +A I ED++ GT ++ + Sbjct: 1074 SYEIAIEAMDGG--GFVAQTKVLIEIIDENDNAPEISIASLSAPIPEDSMPGTVIALIKV 1131 Query: 606 TDADVGLNGRIHYELDPKDREEGSF-VIDPASGVIR--TNKALDRESVATHDLKAVAIDG 662 D D G NG E+D + F ++ +S R T LDRE V +++ +A D Sbjct: 1132 HDQDTGRNG----EVDCQILGAAPFQIVSSSSRYYRIITASFLDREKVPWYNITILATDK 1187 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 G+P SST + + + D+ND+PPVF Y+ EN+ G++I I+A D D G NA V Sbjct: 1188 GSPELSSTKSIKLDLSDVNDNPPVFSKPTYVAYLPENNLPGSSIYRIQAFDFDSGNNAKV 1247 Query: 723 HYSIKGG--DD---SNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIR-AASPPLW 775 YSI D S FS+ G L DYE + E+ R + SPPL Sbjct: 1248 VYSILNTYIQDIPVSAYFSINVVSG----VLYAQRSFDYEQHQMFSMEITARDSGSPPLN 1303 Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG--------RVPAYDADV--TD 825 +++ + I + D NDNAP + + F + P +V A DAD Sbjct: 1304 SNITLIIYIIDQNDNAPEIL-YPSPNGGGSSLFEMVPLASEQGSLITKVIAVDADSGHNS 1362 Query: 826 KLQYRILSGNNANLILLNETTGSM-TLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884 L Y + ++ + +N+ TG + T L+ K+ + ++ DG N ++ L Sbjct: 1363 WLSYHFIPMSDPSPFSINQYTGEIRTCQKPLDRENLKIHKLLLTAFDGGNPVRTGTALIR 1422 Query: 885 RLITE 889 IT+ Sbjct: 1423 IAITD 1427 Score = 310 bits (760), Expect = 5e-82 Identities = 203/626 (32%), Positives = 325/626 (51%), Gaps = 42/626 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++++ D ND+ PVF + A + E G+++ ++A+D D G NA+V Y+I + Sbjct: 1858 RLDISDVNDNPPVFMKSKDVAYLPENNLPGSSIYRIQASDLDTGDNAKVIYSIS-----S 1912 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 ++ ED + F I+ +G L + S D E+V + + + A+D +PV Sbjct: 1913 MDNED---------FPISSYFSINIETGVLYAQRSFDYEQVKEFQIQITASDGGNPVR-- 1961 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S TA I + + D NDN P F+++ Y VS+ E+I + N + + ATD D G N A Y Sbjct: 1962 -SGTALIRIAVTDANDNLPVFTQEVYKVSISENIPI--NSTVLTVNATDRDEGTN-AQSY 2017 Query: 190 AIIGGN----TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 + + S S + ++ L K LD E + L++ A DGG+P R+ T + I Sbjct: 2018 RLSDNQYFRLNEKTNSDLSKTPELVLEKPLDRETQSIHELILTASDGGNPLRTGTALIRI 2077 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY----TMTDKDY 301 + D NDN P F +++ S+SEN PI S++ + A D DEG NA++TY T + Y Sbjct: 2078 IVTDSNDNLPVFTQEVYKVSISENAPINSSVIILTATDKDEGTNAQITYSISKTSENNFY 2137 Query: 302 TG--NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 T N++ I + + LDRETQ ++L++TA+DGGDP ++ TA Sbjct: 2138 TSVFNINPVIYYKIVNTELMLEKPLDRETQKDHELILTASDGGDPVKTGTAIIRIIVTDA 2197 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQ 417 F Y+V ++E+ P + V+ + ATD DE + ++ Y + FSI + Sbjct: 2198 NDNLPVFTKAVYKVSISENIPINSSVLHVNATDRDEGTNAQITYSFIKTSVSSYFSINIE 2257 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAP-VFENAPY 474 G++ + D++Q + + + V A D+G S A + I I D N+ AP + + Sbjct: 2258 T--GVLYAQRSFDYEQHKEFAMHVQAKDNGYPSLSSNATLIIRIIDQNDNAPKILYPSTE 2315 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 S+ E+ PI +TVL V+A+D D G NAQITYS S N H F INP +G I Sbjct: 2316 NMSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVNSL---HASMFSINPTSGEIK 2372 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 TN LL+ E + Y ++V A+DGG + + + + DVNDN PVF + YT + E+ Sbjct: 2373 TNNLLNYEAIRDYEISVQAKDGG--GFVAHSKILVEITDVNDNPPVFIKSAYTIYLPENN 2430 Query: 595 LVGTSVSQVGATDADVGLNGRIHYEL 620 L G ++ ++ A D D+G N ++ Y + Sbjct: 2431 LPGATIYRIHALDLDMGDNAKVIYSI 2456 Score = 272 bits (666), Expect = 1e-70 Identities = 202/624 (32%), Positives = 303/624 (48%), Gaps = 68/624 (10%) Query: 12 NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71 +V D ND+ PVF Y+ S+ E A GT V L ATD D+GKN E Y L Sbjct: 88 HVEDVNDNPPVFNQSVYQCSITENAPKGTLVAKLFATDMDVGKNGETSYEF-----SKLV 142 Query: 72 PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131 PE + +F +D +G + + LD EK Y VL+ A D Sbjct: 143 PE-----------RMLSLFSLDKYTGEVWVKGELDYEKSNTYEVLIDALD---------- 181 Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191 +V ++D NDN P+ + + ++ V ED T ++A I+ D D G N + Sbjct: 182 -----NVTVVDVNDNAPEMTVTSLSLPVPED--ATHGTIVAIIRVRDRDSGNNGKVN--- 231 Query: 192 IGGNTQMQFSID-SLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 +T F I+ + SGD SL+ LD E+ Y++VI A+D G PS S + + + + Sbjct: 232 CYSSTPTLFKINPAFSGDFSLIVNSPLDREKKSEYQVVITAKDEGYPSLSVSMTINVEVS 291 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 DVNDNAP F S + EN P G I V A D+D NA L + D + +V Sbjct: 292 DVNDNAPLFQQSSDTIFIRENNPPGSHIYTVSASDSDINDNAPLFIS----DNSNSVSAM 347 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 + P+S LDRE +++YQ+++TA D G P S + T F Sbjct: 348 LVTAPKSAQPAVDAPLDRENKSEYQVVITAKDEGSPSLSISMTINVEISDVNDNAPLFQQ 407 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITS----QNGRGLIT 424 + + E+ PPG+ + ++A+D+D TG N+ +S+ S + L+ Sbjct: 408 TADTIFIRENNPPGSQIYIVSASDSD---------TGQNSFITYSLKSPSKDNKSKSLVL 458 Query: 425 VA-QPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 V Q LD +++ ++LT++A D G RS T ++I + D N+ AP F + Y S+ E+ Sbjct: 459 VLNQALDREKQASHLLTLTAADCGTPKRSGTTQIRILVQDVNDNAPTFRHPIYRVSIPEN 518 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 +G+ ++V+ ATD D G N I YS SS I + +V Q F I G + LLD Sbjct: 519 YAVGSLIVVLKATDLDEGENGVIEYSFSS-IGSRSV---KQLFKIEKNNGEVHLKGLLDY 574 Query: 542 ETMSGYLLTVTAR-----DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 E Y + V D G+P+LS T + SV D+NDN P+F ++LY +I E+ L Sbjct: 575 ENKKYYEIHVQGNRWQTTDNGIPALSTTAYIYFSVDDINDNPPLFTEELYFFSIAENILP 634 Query: 597 GTSVSQVGATDADVGLNGRIHYEL 620 G+ + QV A+D D G N ++ Y L Sbjct: 635 GSLIFQVSASDKDSGKNAQLLYAL 658 Score = 266 bits (652), Expect = 6e-69 Identities = 211/714 (29%), Positives = 337/714 (47%), Gaps = 68/714 (9%) Query: 174 IKATDADVGANSAIRYAII-----GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIR 228 + A+D+D G NS I Y++ G +I+ +G++ L + + + ++RL + Sbjct: 1 VSASDSDTGQNSFITYSLTESFIEGVPVSSYIAINPHAGEIRLTRPITEAEGDAFRLFVV 60 Query: 229 AQDGGSPSRSNTTQLLINIRD----------VNDNAPRFYTSLFQESVSENVPIGYSIVR 278 A+D G P+ + TQ++I+I+D VNDN P F S++Q S++EN P G + + Sbjct: 61 AEDHGEPAMTALTQIIISIKDSGFARTHVEDVNDNPPVFNQSVYQCSITENAPKGTLVAK 120 Query: 279 VQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA 338 + A D D G N E +Y + + L ++D +G V+ G+LD E Y++L+ A Sbjct: 121 LFATDMDVGKNGETSYEFSKLVPERMLSL-FSLDKYTGEVWVKGELDYEKSNTYEVLIDA 179 Query: 339 TDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR 398 D + T +P + ED GT V + D D N Sbjct: 180 LD------NVTVVDVNDNAPEMTVTSLSLP------VPEDATHGTIVAIIRVRDRDSGNN 227 Query: 399 LHYEITGGNTRGRFSITSQ-NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQI 457 +T F I +G + V PLD +++ Y + ++A D G S + + I Sbjct: 228 GKVNCYS-STPTLFKINPAFSGDFSLIVNSPLDREKKSEYQVVITAKDEGYPSLSVSMTI 286 Query: 458 NI--TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515 N+ +D N+ AP+F+ + T + E+ P G+ + VSA+DSD+ NA + S+ SN Sbjct: 287 NVEVSDVNDNAPLFQQSSDTIFIRENNPPGSHIYTVSASDSDINDNAPL---FISDNSNS 343 Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575 A V P++ + LDRE S Y + +TA+D G PSLS + + + + DVN Sbjct: 344 VSA----MLVTAPKSAQPAVDAPLDRENKSEYQVVITAKDEGSPSLSISMTINVEISDVN 399 Query: 576 DNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA 635 DN P+F+Q T I E+ G+ + V A+D+D G N I Y L ++ S Sbjct: 400 DNAPLFQQTADTIFIRENNPPGSQIYIVSASDSDTGQNSFITYSLKSPSKDNKS-----K 454 Query: 636 SGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695 S V+ N+ALDRE A+H L A D GTP +S T + I ++D+ND+ P F Sbjct: 455 SLVLVLNQALDREKQASHLLTLTAADCGTPKRSGTTQIRILVQDVNDNAPTFRHPIYRVS 514 Query: 696 ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG-GDDSNSFSLETRQGSDKAELVTMVDL 754 I EN +G+ I ++A D DEG N V+ YS G S + + + + L + L Sbjct: 515 IPENYAVGSLIVVLKATDLDEGENGVIEYSFSSIGSRSVKQLFKIEKNNGEVHLKGL--L 572 Query: 755 DYESPRKKYELVIRA--------ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKD 806 DYE+ +K YE+ ++ P L + V D+NDN P+ + F+ ++ Sbjct: 573 DYEN-KKYYEIHVQGNRWQTTDNGIPALSTTAYIYFSVDDINDNPPLFTEELYFFSIAEN 631 Query: 807 CFPVGPFGRVPAYDADVTDKLQYRILSGNNANLI--LLNETTGSMTLSPQLNTN 858 P +V A D D SG NA L+ LL M++S ++ N Sbjct: 632 ILPGSLIFQVSASDKD----------SGKNAQLLYALLESYVEGMSVSHFISIN 675 Score = 264 bits (647), Expect = 2e-68 Identities = 187/615 (30%), Positives = 297/615 (48%), Gaps = 47/615 (7%) Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 +S + S A HV D NDN P F++ Y S+ E+ ++AK+ ATD DVG N Sbjct: 77 ISIKDSGFARTHVE--DVNDNPPVFNQSVYQCSITEN--APKGTLVAKLFATDMDVGKNG 132 Query: 186 AIRYA---IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 Y ++ FS+D +G+V + LDYE+ +Y ++I A D Sbjct: 133 ETSYEFSKLVPERMLSLFSLDKYTGEVWVKGELDYEKSNTYEVLIDALDN---------- 182 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT-YTMTDKDY 301 + + DVNDNAP + V E+ G + ++ D D G N ++ Y+ T + Sbjct: 183 --VTVVDVNDNAPEMTVTSLSLPVPEDATHGTIVAIIRVRDRDSGNNGKVNCYSSTPTLF 240 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 N P S + + LDRE +++YQ+++TA D G P S + T Sbjct: 241 KIN---PAFSGDFS--LIVNSPLDREKKSEYQVVITAKDEGYPSLSVSMTINVEVSDVND 295 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD-EDNRLHYEITGGNTRGRFSITSQNGR 420 F + + E+ PPG+ + T++A+D+D DN + N+ +T+ Sbjct: 296 NAPLFQQSSDTIFIRENNPPGSHIYTVSASDSDINDNAPLFISDNSNSVSAMLVTAPKS- 354 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYAPVFENAPYTASV 478 V PLD + + Y + ++A D G S + + IN I+D N+ AP+F+ T + Sbjct: 355 AQPAVDAPLDRENKSEYQVVITAKDEGSPSLSISMTINVEISDVNDNAPLFQQTADTIFI 414 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 E+ P G+ + +VSA+DSD G N+ ITYSL S + ++ + N+ Sbjct: 415 RENNPPGSQIYIVSASDSDTGQNSFITYSLKSPSKDN-----------KSKSLVLVLNQA 463 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 LDRE + +LLT+TA D G P S TT + I V DVNDN P F+ +Y +I E+ VG+ Sbjct: 464 LDREKQASHLLTLTAADCGTPKRSGTTQIRILVQDVNDNAPTFRHPIYRVSIPENYAVGS 523 Query: 599 SVSQVGATDADVGLNGRIHYELDP--KDREEGSFVIDPASGVIRTNKALDRESVATHDL- 655 + + ATD D G NG I Y + F I+ +G + LD E+ +++ Sbjct: 524 LIVVLKATDLDEGENGVIEYSFSSIGSRSVKQLFKIEKNNGEVHLKGLLDYENKKYYEIH 583 Query: 656 ----KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711 + D G P S+T ++ ++DIND+PP+F + F I+EN G+ I ++ A Sbjct: 584 VQGNRWQTTDNGIPALSTTAYIYFSVDDINDNPPLFTEELYFFSIAENILPGSLIFQVSA 643 Query: 712 HDPDEGPNAVVHYSI 726 D D G NA + Y++ Sbjct: 644 SDKDSGKNAQLLYAL 658 Score = 232 bits (568), Expect = 9e-59 Identities = 218/797 (27%), Positives = 357/797 (44%), Gaps = 101/797 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D ND++P+F+ +RE G+ + T+ A+D DI NA L +D Sbjct: 288 VEVSDVNDNAPLFQQSSDTIFIRENNPPGSHIYTVSASDSDINDNAP------LFISDNS 341 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N A +S A LDRE + Y V++ A D+ SP L Sbjct: 342 NSVSAMLVTAP-------------KSAQPAVDAPLDRENKSEYQVVITAKDEGSP---SL 385 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S + TI+V I D NDN P F + T+ + E+ I + A+D+D G NS I Y+ Sbjct: 386 SISMTINVEISDVNDNAPLFQQTADTIFIRENNPPGSQIYI--VSASDSDTGQNSFITYS 443 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + + + S S + L + LD E+ S+ L + A D G+P RS TTQ+ I ++DV Sbjct: 444 LKSPSKDNK----SKSLVLVLNQALDREKQASHLLTLTAADCGTPKRSGTTQIRILVQDV 499 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDNAP F +++ S+ EN +G IV ++A D DEG N + Y+ + + +V Sbjct: 500 NDNAPTFRHPIYRVSIPENYAVGSLIVVLKATDLDEGENGVIEYSFSSIG-SRSVKQLFK 558 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLV-----TATDGGDPPRSATATXXXXXXXXXXXXXX 365 I+ +G V+ G LD E + Y++ V TD G P S TA Sbjct: 559 IEKNNGEVHLKGLLDYENKKYYEIHVQGNRWQTTDNGIPALSTTAYIYFSVDDINDNPPL 618 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV 425 F Y +AE+ PG+ + ++A+D D +G N + +++ G+ +V Sbjct: 619 FTEELYFFSIAENILPGSLIFQVSASDKD---------SGKNAQLLYALLESYVEGM-SV 668 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA-SVFEDAPI 484 + +S G + ++ DA +A Y A +E P+ Sbjct: 669 SH------------FISINPDSGNVGHLVTKLRAVDA--------DAGYNAWLTYEMDPV 708 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 T L + DS G N ++ ++ +++ V + T ++T K L Sbjct: 709 SNTTLF--SVDSYSGENTYKLVTVGKLDREKSSSYNITVTVTDSGTPPLSTQKTL----- 761 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 + V+ + P+ T+ E+ V +++N P+ ++V +V Sbjct: 762 ---YVEVSDLNDNPPTFEKCTNKEVYKVRISENSPI----------------NSTVIRVN 802 Query: 605 ATDADVGLNGRIHYELDPKDREE---GSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 ATD D GLN +I Y + F I+P +G IRT LDRE+ + +++ ++ D Sbjct: 803 ATDKDEGLNSQITYSFSKTSDNQLYTSIFDINPTNGEIRTTSFLDRENTSQYNITILSTD 862 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 G+P S+ + + I D+ND+ P+F+ Y+SEN+ G++I I A+DPD G NA Sbjct: 863 RGSPKLSTVKHIRLNISDVNDNAPIFKKSTYVAYLSENNLPGSSIYRINAYDPDTGDNAK 922 Query: 722 VHYSIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWND 777 + YSI G + + + S + L DYE K++++ I A SP L ++ Sbjct: 923 IIYSIAGTNIKDIAISSYFSINIETGVLYAQRSFDYEHD-KEFQIGITARDHGSPSLSSN 981 Query: 778 VR--VEILVTDVNDNAP 792 + I+ D NDN P Sbjct: 982 TTLVIHIIDHDANDNIP 998 Score = 192 bits (467), Expect = 2e-46 Identities = 160/552 (28%), Positives = 249/552 (45%), Gaps = 52/552 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V+D ND++P + V E A+ GT V ++ D+D G N +V T + Sbjct: 183 VTVVDVNDNAPEMTVTSLSLPVPEDATHGTIVAIIRVRDRDSGNNGKVNCYSSTPTLFKI 242 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 NP F D +L+ + LDREK + Y V++ A D+ P L Sbjct: 243 NP----------------AFSGD---FSLIVNSPLDREKKSEYQVVITAKDEGYP---SL 280 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S + TI+V + D NDN P F + + T+ + E+ + I + A+D+D+ N+ + + Sbjct: 281 SVSMTINVEVSDVNDNAPLFQQSSDTIFIRENNPPGSH--IYTVSASDSDINDNAPLFIS 338 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + S ++ LD E Y++VI A+D GSPS S + + + I DV Sbjct: 339 DNSNSVSAMLVTAPKSAQPAVDAPLDRENKSEYQVVITAKDEGSPSLSISMTINVEISDV 398 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDNAP F + + EN P G I V A D+D G N+ +TY++ Sbjct: 399 NDNAPLFQQTADTIFIRENNPPGSQIYIVSASDSDTGQNSFITYSLKSPSKDNK------ 452 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 +S + + LDRE QA + L +TA D G P RS T F Sbjct: 453 --SKSLVLVLNQALDREKQASHLLTLTAADCGTPKRSGTTQIRILVQDVNDNAPTFRHPI 510 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRG---RFSITSQNGRGLITV 425 Y V + E+ G+ +V L ATD DE + Y + +R F I NG + + Sbjct: 511 YRVSIPENYAVGSLIVVLKATDLDEGENGVIEYSFSSIGSRSVKQLFKIEKNNGE--VHL 568 Query: 426 AQPLDFKQERRYVLTV-----SATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASV 478 LD++ ++ Y + V TD+G S TA + ++ D N+ P+F Y S+ Sbjct: 569 KGLLDYENKKYYEIHVQGNRWQTTDNGIPALSTTAYIYFSVDDINDNPPLFTEELYFFSI 628 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYS-LSSEISNEAVAHHDQQFVINPQTGAI--TT 535 E+ G+ + VSA+D D G NAQ+ Y+ L S + +V+H INP +G + Sbjct: 629 AENILPGSLIFQVSASDKDSGKNAQLLYALLESYVEGMSVSHF---ISINPDSGNVGHLV 685 Query: 536 NKLLDRETMSGY 547 KL + +GY Sbjct: 686 TKLRAVDADAGY 697 Score = 81.8 bits (193), Expect = 2e-13 Identities = 57/188 (30%), Positives = 94/188 (50%), Gaps = 26/188 (13%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I V D ND++P F Y S+ E + G+ ++ LKATD D G+N +EY+ + Sbjct: 493 RILVQDVNDNAPTFRHPIYRVSIPENYAVGSLIVVLKATDLDEGENGVIEYSFSSI---- 548 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLV-----KATDQAS 124 V+ +F+I+ +G + + LD E Y + V + TD Sbjct: 549 ------------GSRSVKQLFKIEKNNGEVHLKGLLDYENKKYYEIHVQGNRWQTTDNGI 596 Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184 P LS+TA I+ ++ D NDN P F+E+ Y S+ E+I +I ++ A+D D G N Sbjct: 597 PA---LSTTAYIYFSVDDINDNPPLFTEELYFFSIAENI--LPGSLIFQVSASDKDSGKN 651 Query: 185 SAIRYAII 192 + + YA++ Sbjct: 652 AQLLYALL 659 >UniRef50_UPI00004D1B71 Cluster: SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1).; n=1; Xenopus tropicalis|Rep: SH3 adapter protein SPIN90 (NCK-interacting protein with SH3 domain) (SH3 protein interacting with Nck, 90 kDa) (VacA-interacting protein, 54 kDa) (VIP54) (AF3p21) (Diaphanous protein-interacting protein) (Dia-interacting protein 1) (DIP-1). - Xenopus tropicalis Length = 1171 Score = 407 bits (1001), Expect = e-111 Identities = 211/567 (37%), Positives = 309/567 (54%), Gaps = 41/567 (7%) Query: 1356 WRFGGDGMLSFNPLLR-PIQLPWLNALSIRTRQRDAFVMSI----------QLKSGLLHY 1404 ++F G +LS++ I +PW L+ RTR+ D ++ QL SGL+ + Sbjct: 8 YQFNGSSLLSWDFKNDVKISVPWFLGLAFRTRRADGVLLQAHAGQYTTILCQLVSGLISF 67 Query: 1405 SYNG-----ETMYLPMATLSDGAWHRIEIKWL----GTD----ISVTVDYGLRTVLMPML 1451 S + + L ++DG WH ++++ G + IS+ +DYG + + Sbjct: 68 SVSRGSSRTSALLLDQMLVNDGKWHDLQMELRDVRSGRETRYVISINLDYGFYQDTVTV- 126 Query: 1452 ANKIQGQYIGKILIGGLDTTAGLLASDVGFFEGCIQDVRIGTAQS--LLNRPTVRENVRD 1509 +++ G + + IGG+ +G GF EGCIQ VR+G S L +P+ NV+ Sbjct: 127 GSELHGLRVKNLYIGGV---SGPREVQNGF-EGCIQGVRLGETPSGITLPKPSSALNVKP 182 Query: 1510 GCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPC---GAARCVPDQ 1566 GC C + CP S CV W S +C C G G C+ C+L PC G R P Sbjct: 183 GCGVPNMCDSNPCPGNSSCVNEWMSYSCVCHPGYYGENCIDVCQLNPCENRGVCRHQPS- 241 Query: 1567 TPKGYSCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENGKC 1626 P GY+C C + C ++CP GWWG + CGPC CDV +G+ P CNK NG+C Sbjct: 242 APMGYTCECSKNHI--GRYCEHRLDQQCPKGWWGNATCGPCHCDVNKGFDPDCNKTNGQC 299 Query: 1627 HCKENHYKPEGTAECLPCQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAYAEVTP 1686 +CKE HY+P+G+ CLPC CY GS + +C+ TGQC+CRPGVIGR C+ C + +A+V+P Sbjct: 300 NCKEFHYRPKGSETCLPCDCYPIGSSSRACDQETGQCYCRPGVIGRECNNCDSPFAQVSP 359 Query: 1687 NSGCEVVYDGCPRSFAGGVWWPRTKFGVETITDCPPGSSGRATRTCDETKDVPWQDPDMF 1746 SGCEV+YDGCP++ GVWWPRTKFG+ CP GS G A R CD+ K W +PD+F Sbjct: 360 -SGCEVIYDGCPKTLTAGVWWPRTKFGLPAAVPCPKGSLGAAIRHCDDVKG--WLEPDLF 416 Query: 1747 NCTTATFYQLRKQLHKIETGELTMNTFVGVRVAADLSTACANTPRLYGADVVVAEGILLE 1806 NCT+ F +L L +E E +NT ++A L + + +G DV + +L Sbjct: 417 NCTSPAFVELSPMLDGLERNETELNTIEAKKLALRLRSVTDQMDQYFGNDVHITYRLLSY 476 Query: 1807 LMDYELRQAGLNLTHSQDKDYVRNLLKSTNTILNVEYEREWKRIRELTGHGAELLVQKFD 1866 LM YE +Q G LT +QD + NLLK+ ++IL + W+ + HG+ L+ Sbjct: 477 LMQYENKQEGFGLTATQDAQFTENLLKTGSSILTLGNREHWEALLH-NEHGSAGLMNLLW 535 Query: 1867 EYIAVLAESQHDTYTSPFEIVTKDVVI 1893 EY + LA++ TY +P +VT +++I Sbjct: 536 EYSSTLAKNMKLTYLNPVGLVTPNIII 562 Score = 48.0 bits (109), Expect = 0.004 Identities = 33/137 (24%), Positives = 68/137 (49%), Gaps = 15/137 (10%) Query: 2195 SRTNPQCVHWST---LRGSGEWSRVGCHTEIDYDWSPYSEEPLLINCTCNHLSTFAVLVD 2251 +R+ P CV W+ + G W+ C E+ Y + + + C C T+ VL+D Sbjct: 668 NRSKPVCVQWNQSEQVDPLGSWTVKDC--ELVYRNTTH------VRCHCPQFGTYGVLMD 719 Query: 2252 ---EVDVEFIPEPSLLESVTSYTAFSISLPLLLTSWAALCLIRGGAATVSNSIHKHLIFS 2308 D + + ++ SYT+ SISL L+ +++ L ++ G + + IH ++ + Sbjct: 720 GSHREDKQQLEGDLETLAIVSYTSLSISLAALVATFSILTFLK-GLKSNTRGIHSNIAVA 778 Query: 2309 VFMAELLYLIALKARTS 2325 +F++EL++++ + S Sbjct: 779 LFLSELVFVLGINRTES 795 Score = 38.3 bits (85), Expect = 3.0 Identities = 13/34 (38%), Positives = 19/34 (55%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCAD 1350 C S PC + C + W +Y C C G+ G++C D Sbjct: 190 CDSNPCPGNSSCVNEWMSYSCVCHPGYYGENCID 223 >UniRef50_Q4SRY5 Cluster: Chromosome 18 SCAF14485, whole genome shotgun sequence; n=7; Euteleostomi|Rep: Chromosome 18 SCAF14485, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 2244 Score = 407 bits (1001), Expect = e-111 Identities = 277/883 (31%), Positives = 448/883 (50%), Gaps = 54/883 (6%) Query: 3 VPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 V FC+ I + D ND++P F Y++++ GT+V+ + A+D D G NA++EY+I Sbjct: 1331 VGFCVVNVI-LTDINDNAPQFRAADYKSTIASDVPRGTSVVRISASDLDEGSNADIEYSI 1389 Query: 63 ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122 E AD N V++ F I SG ++T+ SL + Y V+A D Sbjct: 1390 E---ADVEN--------------VEENFEIHPTSGLIVTKESLIGLENELYAFFVRAKDT 1432 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 +P S +++ I+ P+F+E Y +V ED+ + I I+A A Sbjct: 1433 GNPPQH---SVVQVNIRIVAPETPIPKFNEAQYRYTVAEDLPIGTE--IDVIQAESAQPL 1487 Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 S ++ + N F +D SG + L K+LD+E + Y+ ++ +Q + Sbjct: 1488 IYSLVKGSTPESNADEVFVVDRDSGALKLQKSLDHETTKWYQFLLHSQTKHENFDIVASV 1547 Query: 243 LL-INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 ++ I ++DVNDN P F + ++ V EN+P G +++V+A D D G N ++ Y++ + Sbjct: 1548 IVNIQVKDVNDNKPVFESDPYEAVVVENLPSGTQVIQVRASDQDSGTNGQVIYSLDARQS 1607 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 + + ++ +GWV T +LDRE +Y + V ATD GD + AT T Sbjct: 1608 SEEISELFAVNSETGWVTTLKELDREKMQRYTIAVLATDQGDRIQHATGTRVEVTVADVN 1667 Query: 362 XXX-XFMPGQYEVELAEDEPPGTPVVT-LTATDADEDN---RLHYEITGGNTRGRFSITS 416 F Y+ ++ED+PP + V+ L+ TDAD ++ +++Y ITGG+ G+F+I Sbjct: 1668 DNPPRFTAEIYKGTVSEDDPPPSGVIAILSTTDADSEDINKQVNYFITGGDPLGQFAIEH 1727 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA 476 + V +PLD +++ Y+L ++A+D G + A V++ + DAN+ +P E A Y+ Sbjct: 1728 IQNEWKVFVKKPLDREEKDNYLLNITASD-GIFTAKATVEVKVLDANDNSPQCEKALYSE 1786 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 SV E++P G +L VSA+D+D+ NAQI Y L S + F I+ TG + T Sbjct: 1787 SVPENSPAGRLILQVSASDADIRSNAQIFYELQGAGS--------ELFTIDSDTGELKTL 1838 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 + LDRE + + A DGG D+ + V DVNDN P F LYT + E+ + Sbjct: 1839 QPLDREEQEEHRFKMRAVDGGGRYCE--ADIHVVVEDVNDNLPQFSADLYTVTVFENTEI 1896 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 GT V+++ A D DVG N I Y L D +G F ID +GVI + LDRE +T++L+ Sbjct: 1897 GTYVAKLLANDVDVGPNSNIIYSL--LDSADGFFSIDEQTGVISLERPLDRELQSTYELR 1954 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 A+A D G P SS V + + DIND+PPVFE T +SE+ +GT + ++A D Sbjct: 1955 ALASDQGLPRLSSVCQVVVSVLDINDNPPVFEHREYTATVSEDVSVGTQLLRVQAASRDT 2014 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV--IRAASPPL 774 N + Y I G++ FS++ R G ++ + LDYE+ + Y V SPPL Sbjct: 2015 EANGEISYGIISGNEHGLFSVDPRTG----DIFVIQPLDYEASHEYYITVEATDGGSPPL 2070 Query: 775 WNDVRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRIL 832 + V I +TDVNDN PV + + + + D ++Y I+ Sbjct: 2071 SDMATVNINLTDVNDNRPVFSQDVYTAVVSEDAELGKTVITVNAEDLDGPSHSHVRYSIV 2130 Query: 833 SGNNANLILLNETTGSMTLSPQLN---TNVPK-LATMEVSVTD 871 GN + ++ G + ++ QL+ N PK + ++++VTD Sbjct: 2131 DGNQGSPFTIDSARGELKVAHQLDRERENRPKGTSVLQLTVTD 2173 Score = 316 bits (776), Expect = 6e-84 Identities = 236/815 (28%), Positives = 377/815 (46%), Gaps = 46/815 (5%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F ID +G + LD E Y + V+ATD + S + + + D NDN P Sbjct: 981 FSIDFNTGVIHVIQPLDFETHPAYKLSVRATDSLTGAH----SDVFVDIILEDVNDNAPV 1036 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG--GNTQMQFSIDSLSG 207 F K Y +V E SV ++ ++ A D+D G N + + ++ G + F+ID +G Sbjct: 1037 FLSKAYHANVSE-ASVVGTRIL-QVDAKDSDTGNNQEVFFQLVEEKGESSDFFTIDRDTG 1094 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 +S + LDYE++R + L +RA D G P+ S+ + I++ D+NDNAP F + ++S Sbjct: 1095 TISTAQLLDYEEIRQHELRVRAVDRGVPALSSEVIVTIDVTDLNDNAPEFTQQTYNSTIS 1154 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 E P G+ I +VQA DAD L + T +GN DL +ID +G + S Sbjct: 1155 ELAPRGHFITQVQASDADSSDKDNLLFFFT----SGNEDLNFSIDKHTGAILISNHRRVH 1210 Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387 Q Y L V+ +DG ++A F ++ VEL E TPV Sbjct: 1211 MQPFYNLSVSVSDG---VFRSSAAVLVTVIGANFHSPTFSQTEFVVELVEHSEIYTPVAE 1267 Query: 388 LTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS--A 443 ATDADE ++ Y+I + +FS+ N G I + LD + V+ +S A Sbjct: 1268 AKATDADEGIYGQIRYQIVNDFAKDKFSV---NENGEIFTLESLDRENNMEKVVPISLVA 1324 Query: 444 TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503 D GG+ +V + +TD N+ AP F A Y +++ D P GT+V+ +SA+D D G NA Sbjct: 1325 RDGGGKVGFCVVNVILTDINDNAPQFRAADYKSTIASDVPRGTSVVRISASDLDEGSNAD 1384 Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD 563 I YS+ +++ N ++ F I+P +G I T + L Y V A+D G P Sbjct: 1385 IEYSIEADVENV-----EENFEIHPTSGLIVTKESLIGLENELYAFFVRAKDTGNPPQHS 1439 Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK 623 V I +V P F + Y + ED +GT + + A A + + P+ Sbjct: 1440 VVQVNIRIVAPETPIPKFNEAQYRYTVAEDLPIGTEIDVIQAESAQPLIYSLVKGS-TPE 1498 Query: 624 DREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS----STVIVHIKIED 679 + FV+D SG ++ K+LD E+ + + T ++ ++VIV+I+++D Sbjct: 1499 SNADEVFVVDRDSGALKLQKSLDHETTKWYQF---LLHSQTKHENFDIVASVIVNIQVKD 1555 Query: 680 INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLET 739 +ND+ PVFESD + EN P GT + ++RA D D G N V YS+ S S Sbjct: 1556 VNDNKPVFESDPYEAVVVENLPSGTQVIQVRASDQDSGTNGQVIYSLDARQSSEEISELF 1615 Query: 740 RQGSDKAELVTMVDLDYESPRKKYELVIRAASP----PLWNDVRVEILVTDVNDNAP-VM 794 S+ + T+ +LD E ++Y + + A RVE+ V DVNDN P Sbjct: 1616 AVNSETGWVTTLKELDREK-MQRYTIAVLATDQGDRIQHATGTRVEVTVADVNDNPPRFT 1674 Query: 795 KDFQIIFNNYKDCFPVGPFGRVPAYDADVTD---KLQYRILSGNNANLILLN--ETTGSM 849 + + D P G + DAD D ++ Y I G+ + + + Sbjct: 1675 AEIYKGTVSEDDPPPSGVIAILSTTDADSEDINKQVNYFITGGDPLGQFAIEHIQNEWKV 1734 Query: 850 TLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884 + L+ + ++ +DG+ KA +++ V Sbjct: 1735 FVKKPLDREEKDNYLLNITASDGIFTAKATVEVKV 1769 Score = 299 bits (734), Expect = 7e-79 Identities = 261/947 (27%), Positives = 425/947 (44%), Gaps = 70/947 (7%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 D ND++PVF + Y A+V E + GT +L + A D D G N EV + + ++ Sbjct: 1029 DVNDNAPVFLSKAYHANVSEASVVGTRILQVDAKDSDTGNNQEVFFQLVEEKGES----- 1083 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134 D F ID +G + T LD E++ ++ + V+A D+ P LSS Sbjct: 1084 ------------SDFFTIDRDTGTISTAQLLDYEEIRQHELRVRAVDRGVPA---LSSEV 1128 Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194 + +++ D NDN P+F+++TY ++ E I +++A+DAD + + G Sbjct: 1129 IVTIDVTDLNDNAPEFTQQTYNSTISE--LAPRGHFITQVQASDADSSDKDNLLFFFTSG 1186 Query: 195 NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNA 254 N + FSID +G + + Y L + DG S + +L+ + N ++ Sbjct: 1187 NEDLNFSIDKHTGAILISNHRRVHMQPFYNLSVSVSDGVFRS---SAAVLVTVIGANFHS 1243 Query: 255 PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR 314 P F + F + E+ I + +A DADEG+ ++ Y + + D+ + +++ Sbjct: 1244 PTFSQTEFVVELVEHSEIYTPVAEAKATDADEGIYGQIRYQIVN-DFAKD---KFSVN-E 1298 Query: 315 SGWVYTSGQLDRETQAK--YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE 372 +G ++T LDRE + + + A DGG + F Y+ Sbjct: 1299 NGEIFTLESLDRENNMEKVVPISLVARDGGG--KVGFCVVNVILTDINDNAPQFRAADYK 1356 Query: 373 VELAEDEPPGTPVVTLTATDADEDNR--LHYEITGG--NTRGRFSITSQNGRGLITVAQP 428 +A D P GT VV ++A+D DE + + Y I N F I + GLI + Sbjct: 1357 STIASDVPRGTSVVRISASDLDEGSNADIEYSIEADVENVEENFEIHPTS--GLIVTKES 1414 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV--FENAPYTASVFEDAPIGT 486 L + Y V A D+G ++VQ+NI P+ F A Y +V ED PIGT Sbjct: 1415 LIGLENELYAFFVRAKDTGNPPQHSVVQVNIRIVAPETPIPKFNEAQYRYTVAEDLPIGT 1474 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 + V+ A + + YSL + E+ A D+ FV++ +GA+ K LD ET Sbjct: 1475 EIDVIQAESAQ-----PLIYSLVKGSTPESNA--DEVFVVDRDSGALKLQKSLDHETTKW 1527 Query: 547 Y--LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 Y LL + ++ V I V DVNDN+PVF+ Y A ++E+ GT V QV Sbjct: 1528 YQFLLHSQTKHENFDIVASVI-VNIQVKDVNDNKPVFESDPYEAVVVENLPSGTQVIQVR 1586 Query: 605 ATDADVGLNGRIHYELDPKDREE---GSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 A+D D G NG++ Y LD + E F ++ +G + T K LDRE + + + +A D Sbjct: 1587 ASDQDSGTNGQVIYSLDARQSSEEISELFAVNSETGWVTTLKELDREKMQRYTIAVLATD 1646 Query: 662 GGTPPQSST-VIVHIKIEDINDSPPVFESDCLTFYISENSPIGT-TIGEIRAHDPD-EGP 718 G Q +T V + + D+ND+PP F ++ +SE+ P + I + D D E Sbjct: 1647 QGDRIQHATGTRVEVTVADVNDNPPRFTAEIYKGTVSEDDPPPSGVIAILSTTDADSEDI 1706 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDV 778 N V+Y I GGD F++E Q K + LD E + Y L I A+ Sbjct: 1707 NKQVNYFITGGDPLGQFAIEHIQNEWK--VFVKKPLDREE-KDNYLLNITASDGIFTAKA 1763 Query: 779 RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADVTDKLQ-YRILSGNN 836 VE+ V D NDN+P + + + + P G +V A DAD+ Q + L G Sbjct: 1764 TVEVKVLDANDNSPQCEK-ALYSESVPENSPAGRLILQVSASDADIRSNAQIFYELQGAG 1822 Query: 837 ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSI 896 + L ++ TG + L+ + ++ DG + + ++ E++ N Sbjct: 1823 SELFTIDSDTGELKTLQPLDREEQEEHRFKMRAVDGGGR---YCEADIHVVVEDVNDNLP 1879 Query: 897 TVRLNDMTAEQFLSPLLGFFIDGLAA--IIPCPKENIYIFSVQDDTD 941 + T F + +G ++ L A + P NI I+S+ D D Sbjct: 1880 QFSADLYTVTVFENTEIGTYVAKLLANDVDVGPNSNI-IYSLLDSAD 1925 Score = 297 bits (728), Expect = 4e-78 Identities = 248/881 (28%), Positives = 396/881 (44%), Gaps = 68/881 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V+ N HSP F ++ + E + T V KATD D G ++ Y I Sbjct: 1234 VTVIGANFHSPTFSQTEFVVELVEHSEIYTPVAEAKATDADEGIYGQIRYQI-------- 1285 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVK--ATDQASPVSD 128 +D F ++ +G + T SLDRE V + A D V Sbjct: 1286 -----------VNDFAKDKFSVN-ENGEIFTLESLDRENNMEKVVPISLVARDGGGKVG- 1332 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 ++V + D NDN PQF Y ++ D V + +I A+D D G+N+ I Sbjct: 1333 ----FCVVNVILTDINDNAPQFRAADYKSTIASD--VPRGTSVVRISASDLDEGSNADIE 1386 Query: 189 YAIIGG--NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 Y+I N + F I SG + ++L + Y +RA+D G+P + + Q+ I Sbjct: 1387 YSIEADVENVEENFEIHPTSGLIVTKESLIGLENELYAFFVRAKDTGNPPQHSVVQVNIR 1446 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT-GNV 305 I P+F + ++ +V+E++PIG I +QA A L Y++ N Sbjct: 1447 IVAPETPIPKFNEAQYRYTVAEDLPIGTEIDVIQAESAQP-----LIYSLVKGSTPESNA 1501 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLV-TATDGGDPPRSATATXXXXXXXXXXXXX 364 D +D SG + LD ET YQ L+ + T + A+ Sbjct: 1502 DEVFVVDRDSGALKLQKSLDHETTKWYQFLLHSQTKHENFDIVASVIVNIQVKDVNDNKP 1561 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFS--ITSQNGR 420 F YE + E+ P GT V+ + A+D D + ++ Y + + S + Sbjct: 1562 VFESDPYEAVVVENLPSGTQVIQVRASDQDSGTNGQVIYSLDARQSSEEISELFAVNSET 1621 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM---VQINITDANNYAPVFENAPYTAS 477 G +T + LD ++ +RY + V ATD G R A V++ + D N+ P F Y + Sbjct: 1622 GWVTTLKELDREKMQRYTIAVLATDQGDRIQHATGTRVEVTVADVNDNPPRFTAEIYKGT 1681 Query: 478 VFEDAPIGTTVL-VVSATDSDV-GINAQITYSLSS--EISNEAVAHHDQQFVINPQTGAI 533 V ED P + V+ ++S TD+D IN Q+ Y ++ + A+ H ++ + Sbjct: 1682 VSEDDPPPSGVIAILSTTDADSEDINKQVNYFITGGDPLGQFAIEHIQNEW-------KV 1734 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593 K LDRE YLL +TA DG + VE+ V+D NDN P ++ LY+ ++ E+ Sbjct: 1735 FVKKPLDREEKDNYLLNITASDG---IFTAKATVEVKVLDANDNSPQCEKALYSESVPEN 1791 Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653 + G + QV A+DAD+ N +I YEL E F ID +G ++T + LDRE H Sbjct: 1792 SPAGRLILQVSASDADIRSNAQIFYELQGAGSE--LFTIDSDTGELKTLQPLDREEQEEH 1849 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713 K A+DGG + +H+ +ED+ND+ P F +D T + EN+ IGT + ++ A+D Sbjct: 1850 RFKMRAVDGGG--RYCEADIHVVVEDVNDNLPQFSADLYTVTVFENTEIGTYVAKLLAND 1907 Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP 773 D GPN+ + YS+ D FS++ + G E +D + +S + L P Sbjct: 1908 VDVGPNSNIIYSLLDSADG-FFSIDEQTGVISLE--RPLDRELQSTYELRALASDQGLPR 1964 Query: 774 LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY--DADVTDKLQYRI 831 L + +V + V D+NDN PV + + +D RV A D + ++ Y I Sbjct: 1965 LSSVCQVVVSVLDINDNPPVFEHREYTATVSEDVSVGTQLLRVQAASRDTEANGEISYGI 2024 Query: 832 LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 +SGN L ++ TG + + L+ + V TDG Sbjct: 2025 ISGNEHGLFSVDPRTGDIFVIQPLDYEASHEYYITVEATDG 2065 Score = 274 bits (673), Expect = 2e-71 Identities = 206/771 (26%), Positives = 356/771 (46%), Gaps = 52/771 (6%) Query: 138 VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQ 197 + +ID N++ PQFSEK Y V+V ED + +I A+D D + + + ++ Sbjct: 198 IRVIDTNNHRPQFSEKFYEVNVAED--TPPGTEVLQISASDRD--EKNKLTFTLLSSTDP 253 Query: 198 M---QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNA 254 +F +D +G + +TLD+E + + L + +D P + N ++++N+ D NDNA Sbjct: 254 FSLRKFRLDPGTGTLYTAETLDHETMHHHILTVMVRDQDIPVKRNLVRVIVNVDDTNDNA 313 Query: 255 PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR 314 P F + F V E+ +G ++++V A D D+G NAE+ Y++ +GN +IDP+ Sbjct: 314 PWFVGAPFSGRVFESAAVGSAVLQVTARDKDKGRNAEVVYSLE----SGNFANTFSIDPK 369 Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374 G + + +LDR+++A+Y+L V A+D G PP S TA F ++ + Sbjct: 370 LGTITVAKELDRDSKAQYELTVKASDNGVPPLSTTAPVRIAVTVSDNAAPRFTEREFSAD 429 Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434 ++E PG+ V +TA+ + + Y+I GN F I + G++ +PLD++ Sbjct: 430 VSESAHPGSFVALVTAS---SQSSVFYQIKAGNINNAFDINPNS--GVVVTQRPLDYETT 484 Query: 435 RRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV------ 488 +Y L + T+ G + +++ D N+ AP+F + V E AP+ + V Sbjct: 485 AQYTLVIQGTNMAGLGTNTTLLVHLKDENDNAPIFIQKEFRGVVSESAPVNSVVLTRENT 544 Query: 489 -LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 LVV A+D+D NA + Y + E AH+ F I+ TGAI LD E + + Sbjct: 545 PLVVRASDADGDQNAMLIYQIV-----EPFAHN--YFAIDSNTGAIRITTALDYEERNTF 597 Query: 548 LLTVTARDGGVPSLSDTT--DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 TV D G+P L T +V I V DVND PVF Q+ Y A ++ G V Q+ A Sbjct: 598 HFTVQVHDLGIPRLFAETAANVTIEVTDVNDCPPVFSQKTYEATVITPTYKGVKVIQINA 657 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 TD+D G N ++ + + + F +DP +G+I S ++LK DG Sbjct: 658 TDSDSGPNAKLLLSISEGNIGD-KFKMDPTTGIISVQNVTQLRS--RYELKVRVSDGRF- 713 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 SS V I +++ ++ F + ++ ENS T+ I A N + Y+ Sbjct: 714 --SSVATVKINVKENKENKLKFTKESYKAFVQENSSEKKTLEVIAA--VGNQVNEPLFYN 769 Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND---VRVEI 782 I D F + G T + D E+ + +E+V+ D V + + Sbjct: 770 ILNPD--KKFEISRTSG---VVSTTGIPFDREA-QDTFEIVVEVTREGQSEDGAHVLLTV 823 Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILL 842 +V D NDN P+ + D +V A D D+ + + L + + Sbjct: 824 MVEDANDNRPMFVNLPYHALVQMDAEEGHLIRQVTAVDRDMGQNAEIQYLLKEHQEFFQI 883 Query: 843 NETTGSMTLSPQLNTNV--PKLATMEVSVTDGVNEIKAMMQLSVRLITEEM 891 + +G ++L +L + V+ +G + A +++ V ++ + M Sbjct: 884 S-PSGEISLKKKLQKESLNTDFVIVVVAQDNGNPALSAEVEVPVTVVNKAM 933 Score = 261 bits (640), Expect = 2e-67 Identities = 268/961 (27%), Positives = 433/961 (45%), Gaps = 95/961 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NV D ND++P F + V E A+ G+ VL + A D+D G+NAEV Y++E Sbjct: 304 VNVDDTNDNAPWFVGAPFSGRVFESAAVGSAVLQVTARDKDKGRNAEVVYSLE------- 356 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F ID + G + LDR+ A+Y + VKA+D P L Sbjct: 357 ------------SGNFANTFSIDPKLGTITVAKELDRDSKAQYELTVKASDNGVP---PL 401 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+TA + + + ++ P+F+E+ ++ V E S +A + A+ + S++ Y Sbjct: 402 STTAPVRIAVTVSDNAAPRFTEREFSADVSE--SAHPGSFVALVTAS-----SQSSVFYQ 454 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I GN F I+ SG V + LDYE Y LVI+ + +NTT LL++++D Sbjct: 455 IKAGNINNAFDINPNSGVVVTQRPLDYETTAQYTLVIQGTNMAGLG-TNTT-LLVHLKDE 512 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVR-------VQAYDADEGVNAELTYTMTDKDYTG 303 NDNAP F F+ VSE+ P+ ++ V+A DAD NA L Y + + + Sbjct: 513 NDNAPIFIQKEFRGVVSESAPVNSVVLTRENTPLVVRASDADGDQNAMLIYQIVE-PFAH 571 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA--TATXXXXXXXXXX 361 N ID +G + + LD E + + V D G P A A Sbjct: 572 NY---FAIDSNTGAIRITTALDYEERNTFHFTVQVHDLGIPRLFAETAANVTIEVTDVND 628 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNG 419 F YE + G V+ + ATD+D + +L I+ GN +F + Sbjct: 629 CPPVFSQKTYEATVITPTYKGVKVIQINATDSDSGPNAKLLLSISEGNIGDKFKMDPTT- 687 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479 G+I+V + RY L V +D G S A V+IN+ + F Y A V Sbjct: 688 -GIISVQNVTQLRS--RYELKVRVSD-GRFSSVATVKINVKENKENKLKFTKESYKAFVQ 743 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL- 538 E++ T+ V++A + V N + Y+ + + D++F I+ +G ++T + Sbjct: 744 ENSSEKKTLEVIAAVGNQV--NEPLFYN---------ILNPDKKFEISRTSGVVSTTGIP 792 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 DRE + + V G + + V D NDN P+F Y A + DA G Sbjct: 793 FDREAQDTFEIVVEVTREGQSEDGAHVLLTVMVEDANDNRPMFVNLPYHALVQMDAEEGH 852 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT-HDLKA 657 + QV A D D+G N I Y L K+ +E F I P SG I K L +ES+ T + Sbjct: 853 LIRQVTAVDRDMGQNAEIQYLL--KEHQE-FFQISP-SGEISLKKKLQKESLNTDFVIVV 908 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 VA D G P S+ V V + + +N + P FE T I EN + T + ++A++ EG Sbjct: 909 VAQDNGNPALSAEVEVPVTV--VNKAMPAFEKAFYTIEIPENIQLHTPVLHVQANN-SEG 965 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--PPLW 775 P V Y+I GD FS++ G + + LD+E+ Y+L +RA Sbjct: 966 PRIV--YTISEGDPFKQFSIDFNTG----VIHVIQPLDFET-HPAYKLSVRATDSLTGAH 1018 Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADV--TDKLQYRIL 832 +DV V+I++ DVNDNAPV + N + VG +V A D+D ++ ++++ Sbjct: 1019 SDVFVDIILEDVNDNAPVFLS-KAYHANVSEASVVGTRILQVDAKDSDTGNNQEVFFQLV 1077 Query: 833 --SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITE 889 G +++ ++ TG+++ + L+ + + V D GV + + + +++ +T+ Sbjct: 1078 EEKGESSDFFTIDRDTGTISTAQLLDYEEIRQHELRVRAVDRGVPALSSEVIVTID-VTD 1136 Query: 890 EMLLNSITVRLNDMTAEQFLSPLL--GFFIDGLAA--IIPCPKENIYIFSVQDDTDVTGN 945 LN T +S L G FI + A K+N+ F + D+ + Sbjct: 1137 ---LNDNAPEFTQQTYNSTISELAPRGHFITQVQASDADSSDKDNLLFFFTSGNEDLNFS 1193 Query: 946 I 946 I Sbjct: 1194 I 1194 Score = 260 bits (636), Expect = 5e-67 Identities = 236/875 (26%), Positives = 385/875 (44%), Gaps = 59/875 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +++ D ND++P+F +++ V E A + VLT + T + + +D Sbjct: 507 VHLKDENDNAPIFIQKEFRGVVSESAPVNSVVLTRENTP------------LVVRASDAD 554 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 ++A + F ID +GA+ +LD E+ + V+ D P RL Sbjct: 555 GDQNAMLIYQIVEPFAHNYFAIDSNTGAIRITTALDYEERNTFHFTVQVHDLGIP---RL 611 Query: 131 --SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV-IAKIKATDADVGANSAI 187 + A + + + D ND P FS+KTY +V I+ T V + +I ATD+D G N+ + Sbjct: 612 FAETAANVTIEVTDVNDCPPVFSQKTYEATV---ITPTYKGVKVIQINATDSDSGPNAKL 668 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGGSPSRSNTTQLLIN 246 +I GN +F +D +G +S+ Q+RS Y L +R DG S+ + IN Sbjct: 669 LLSISEGNIGDKFKMDPTTGIISVQNVT---QLRSRYELKVRVSDGRF---SSVATVKIN 722 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 +++ +N +F ++ V EN ++ + A VN L Y + N D Sbjct: 723 VKENKENKLKFTKESYKAFVQENSSEKKTLEVIAA--VGNQVNEPLFYNIL------NPD 774 Query: 307 LPITIDPRSGWVYTSG-QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 I SG V T+G DRE Q ++++V T G A Sbjct: 775 KKFEISRTSGVVSTTGIPFDREAQDTFEIVVEVTREGQSEDGAHVLLTVMVEDANDNRPM 834 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV 425 F+ Y + D G + +TA D D + + F I+ L Sbjct: 835 FVNLPYHALVQMDAEEGHLIRQVTAVDRDMGQNAEIQYLLKEHQEFFQISPSGEISLKKK 894 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 Q + +V+ V A D+G + +A V++ +T N P FE A YT + E+ + Sbjct: 895 LQKESLNTD--FVIVVVAQDNGNPALSAEVEVPVTVVNKAMPAFEKAFYTIEIPENIQLH 952 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 T VL V A +S+ +I Y++S +QF I+ TG I + LD ET Sbjct: 953 TPVLHVQANNSE---GPRIVYTISE-------GDPFKQFSIDFNTGVIHVIQPLDFETHP 1002 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 Y L+V A D + SD V+I + DVNDN PVF + Y AN+ E ++VGT + QV A Sbjct: 1003 AYKLSVRATDSLTGAHSDVF-VDIILEDVNDNAPVFLSKAYHANVSEASVVGTRILQVDA 1061 Query: 606 TDADVGLNGRIHYEL-DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 D+D G N + ++L + K F ID +G I T + LD E + H+L+ A+D G Sbjct: 1062 KDSDTGNNQEVFFQLVEEKGESSDFFTIDRDTGTISTAQLLDYEEIRQHELRVRAVDRGV 1121 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 P SS VIV I + D+ND+ P F ISE +P G I +++A D D + + Sbjct: 1122 PALSSEVIVTIDVTDLNDNAPEFTQQTYNSTISELAPRGHFITQVQASDADSSDKDNLLF 1181 Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILV 784 G++ +FS++ G A L++ + P Y L + + + V + V Sbjct: 1182 FFTSGNEDLNFSIDKHTG---AILISNHRRVHMQP--FYNLSVSVSDGVFRSSAAVLVTV 1236 Query: 785 TDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILL 842 N ++P + + + P A DAD + +++Y+I++ + + Sbjct: 1237 IGANFHSPTFSQTEFVVELVEHSEIYTPVAEAKATDADEGIYGQIRYQIVNDFAKDKFSV 1296 Query: 843 NETTGSMTL-SPQLNTNVPKLATMEVSVTDGVNEI 876 NE TL S N+ K+ + + DG ++ Sbjct: 1297 NENGEIFTLESLDRENNMEKVVPISLVARDGGGKV 1331 Score = 237 bits (581), Expect = 2e-60 Identities = 223/802 (27%), Positives = 352/802 (43%), Gaps = 79/802 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V+D N+H P F + YE +V E GT VL + A+D+D KN ++ +T+ L + D Sbjct: 198 IRVIDTNNHRPQFSEKFYEVNVAEDTPPGTEVLQISASDRD-EKN-KLTFTL-LSSTDPF 254 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + FR+D +G L T +LD E + + + V DQ PV L Sbjct: 255 SLRK---------------FRLDPGTGTLYTAETLDHETMHHHILTVMVRDQDIPVKRNL 299 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + VN+ D NDN P F ++ V E +V + ++ A D D G N+ + Y+ Sbjct: 300 ---VRVIVNVDDTNDNAPWFVGAPFSGRVFESAAV--GSAVLQVTARDKDKGRNAEVVYS 354 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + GN FSID G +++ K LD + Y L ++A D G P S T + I + Sbjct: 355 LESGNFANTFSIDPKLGTITVAKELDRDSKAQYELTVKASDNGVPPLSTTAPVRIAVTVS 414 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 ++ APRF F VSE+ G + V A + + Y + GN++ Sbjct: 415 DNAAPRFTEREFSADVSESAHPGSFVALVTA-----SSQSSVFYQIK----AGNINNAFD 465 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I+P SG V T LD ET A+Y L++ T+ T F+ + Sbjct: 466 INPNSGVVVTQRPLDYETTAQYTLVIQGTNMAG--LGTNTTLLVHLKDENDNAPIFIQKE 523 Query: 371 YEVELAEDEPPGTPVVT-------LTATDADEDNR--LHYEITGGNTRGRFSITSQNGRG 421 + ++E P + V+T + A+DAD D L Y+I F+I S G Sbjct: 524 FRGVVSESAPVNSVVLTRENTPLVVRASDADGDQNAMLIYQIVEPFAHNYFAIDSNTGAI 583 Query: 422 LITVAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNYAPVFENAPYTAS 477 IT A LD+++ + TV D G A V I +TD N+ PVF Y A+ Sbjct: 584 RITTA--LDYEERNTFHFTVQVHDLGIPRLFAETAANVTIEVTDVNDCPPVFSQKTYEAT 641 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 V G V+ ++ATDSD G NA++ S+S + +F ++P TG I+ Sbjct: 642 VITPTYKGVKVIQINATDSDSGPNAKLLLSISE-------GNIGDKFKMDPTTGIISVQN 694 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 + + S Y L V DG S V+I+V + +N+ F ++ Y A + E++ Sbjct: 695 V--TQLRSRYELKVRVSDG---RFSSVATVKINVKENKENKLKFTKESYKAFVQENSSEK 749 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK-ALDRESVATHDLK 656 ++ + A V N + Y + D++ F I SGV+ T DRE+ T ++ Sbjct: 750 KTLEVIAAVGNQV--NEPLFYNILNPDKK---FEISRTSGVVSTTGIPFDREAQDTFEIV 804 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 G + V++ + +ED ND+ P+F + + ++ G I ++ A D D Sbjct: 805 VEVTREGQSEDGAHVLLTVMVEDANDNRPMFVNLPYHALVQMDAEEGHLIRQVTAVDRDM 864 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPP 773 G NA + Y +K + F + S E+ L ES + +V+ A +P Sbjct: 865 GQNAEIQYLLK--EHQEFFQI-----SPSGEISLKKKLQKESLNTDFVIVVVAQDNGNPA 917 Query: 774 LWNDVRVEILVTDVNDNAPVMK 795 L VE+ VT VN P + Sbjct: 918 L--SAEVEVPVTVVNKAMPAFE 937 Score = 196 bits (477), Expect = 1e-47 Identities = 160/571 (28%), Positives = 259/571 (45%), Gaps = 40/571 (7%) Query: 233 GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292 G+ + + +LI + D N++ P+F ++ +V+E+ P G ++++ A D DE +L Sbjct: 186 GTKALHHLLLVLIRVIDTNNHRPQFSEKFYEVNVAEDTPPGTEVLQISASDRDE--KNKL 243 Query: 293 TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352 T+T+ ++ +DP +G +YT+ LD ET + L V D P + Sbjct: 244 TFTLLSSTDPFSL-RKFRLDPGTGTLYTAETLDHETMHHHILTVMVRDQDIPVKRNLVRV 302 Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRG 410 F+ + + E G+ V+ +TA D D+ Y + GN Sbjct: 303 IVNVDDTNDNAPWFVGAPFSGRVFESAAVGSAVLQVTARDKDKGRNAEVVYSLESGNFAN 362 Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPV 468 FSI + G ITVA+ LD + +Y LTV A+D+G S TA V+I +T ++N AP Sbjct: 363 TFSIDPK--LGTITVAKELDRDSKAQYELTVKASDNGVPPLSTTAPVRIAVTVSDNAAPR 420 Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528 F ++A V E A G+ V +V+A+ + + Y + + N A F INP Sbjct: 421 FTEREFSADVSESAHPGSFVALVTASS-----QSSVFYQIKAGNINNA-------FDINP 468 Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588 +G + T + LD ET + Y L + + + L T + + + D NDN P+F Q+ + Sbjct: 469 NSGVVVTQRPLDYETTAQYTLVIQGTN--MAGLGTNTTLLVHLKDENDNAPIFIQKEFRG 526 Query: 589 NIMEDALVGTSVSQ-------VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641 + E A V + V V A+DAD N + Y++ + F ID +G IR Sbjct: 527 VVSESAPVNSVVLTRENTPLVVRASDADGDQNAMLIYQI-VEPFAHNYFAIDSNTGAIRI 585 Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE--DINDSPPVFESDCLTFYISEN 699 ALD E T D G P + ++ IE D+ND PPVF + Sbjct: 586 TTALDYEERNTFHFTVQVHDLGIPRLFAETAANVTIEVTDVNDCPPVFSQKTYEATVITP 645 Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759 + G + +I A D D GPNA + SI G+ + F ++ G + VT + Sbjct: 646 TYKGVKVIQINATDSDSGPNAKLLLSISEGNIGDKFKMDPTTGIISVQNVTQL------- 698 Query: 760 RKKYELVIRAASPPLWNDVRVEILVTDVNDN 790 R +YEL +R + + V+I V + +N Sbjct: 699 RSRYELKVRVSDGRFSSVATVKINVKENKEN 729 Score = 173 bits (420), Expect = 8e-41 Identities = 128/413 (30%), Positives = 203/413 (49%), Gaps = 27/413 (6%) Query: 454 MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513 +V I + D NN+ P F Y +V ED P GT VL +SA+D D ++T++L S Sbjct: 195 LVLIRVIDTNNHRPQFSEKFYEVNVAEDTPPGTEVLQISASDRDE--KNKLTFTLLSSTD 252 Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 ++ ++F ++P TG + T + LD ETM ++LTV RD +P + V ++V D Sbjct: 253 PFSL----RKFRLDPGTGTLYTAETLDHETMHHHILTVMVRDQDIPVKRNLVRVIVNVDD 308 Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633 NDN P F ++ + E A VG++V QV A D D G N + Y L+ +F ID Sbjct: 309 TNDNAPWFVGAPFSGRVFESAAVGSAVLQVTARDKDKGRNAEVVYSLE-SGNFANTFSID 367 Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693 P G I K LDR+S A ++L A D G PP S+T V I + +++ P F + Sbjct: 368 PKLGTITVAKELDRDSKAQYELTVKASDNGVPPLSTTAPVRIAVTVSDNAAPRFTEREFS 427 Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753 +SE++ G+ + + A + V Y IK G+ +N+F + G +VT Sbjct: 428 ADVSESAHPGSFVALVTA-----SSQSSVFYQIKAGNINNAFDINPNSG----VVVTQRP 478 Query: 754 LDYESPRKKYELVIRAAS-PPLWNDVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFPV 810 LDYE+ +Y LVI+ + L + + + + D NDNAP + K+F+ + + V Sbjct: 479 LDYET-TAQYTLVIQGTNMAGLGTNTTLLVHLKDENDNAPIFIQKEFRGVVSESAPVNSV 537 Query: 811 ------GPF-GRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 P R D D L Y+I+ N ++ TG++ ++ L+ Sbjct: 538 VLTRENTPLVVRASDADGDQNAMLIYQIVEPFAHNYFAIDSNTGAIRITTALD 590 Score = 125 bits (301), Expect = 2e-26 Identities = 89/320 (27%), Positives = 156/320 (48%), Gaps = 15/320 (4%) Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV--GLNG 614 G +L V I V+D N++ P F ++ Y N+ ED GT V Q+ A+D D L Sbjct: 186 GTKALHHLLLVLIRVIDTNNHRPQFSEKFYEVNVAEDTPPGTEVLQISASDRDEKNKLTF 245 Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674 + DP + F +DP +G + T + LD E++ H L + D P + + V V Sbjct: 246 TLLSSTDPFSLRK--FRLDPGTGTLYTAETLDHETMHHHILTVMVRDQDIPVKRNLVRVI 303 Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734 + ++D ND+ P F + + E++ +G+ + ++ A D D+G NA V YS++ G+ +N+ Sbjct: 304 VNVDDTNDNAPWFVGAPFSGRVFESAAVGSAVLQVTARDKDKGRNAEVVYSLESGNFANT 363 Query: 735 FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNA 791 FS++ + G+ + +LD +S + +YEL ++A+ PPL V I VT ++ A Sbjct: 364 FSIDPKLGT----ITVAKELDRDS-KAQYELTVKASDNGVPPLSTTAPVRIAVTVSDNAA 418 Query: 792 PVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTL 851 P + + + + P G F V A + Y+I +GN N +N +G + Sbjct: 419 PRFTEREFSADVSESAHP-GSF--VALVTASSQSSVFYQIKAGNINNAFDINPNSGVVVT 475 Query: 852 SPQLNTNVPKLATMEVSVTD 871 L+ T+ + T+ Sbjct: 476 QRPLDYETTAQYTLVIQGTN 495 Score = 117 bits (282), Expect = 4e-24 Identities = 81/247 (32%), Positives = 119/247 (48%), Gaps = 36/247 (14%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 ++VLD ND+ PVFE ++Y A+V E S GT +L ++A +D N E+ Y I Sbjct: 1973 VSVLDINDNPPVFEHREYTATVSEDVSVGTQLLRVQAASRDTEANGEISYGI-------- 2024 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +F +D R+G + LD E Y + V+ATD SP L Sbjct: 2025 -----------ISGNEHGLFSVDPRTGDIFVIQPLDYEASHEYYITVEATDGGSPP---L 2070 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S AT+++N+ D NDN P FS+ YT V ED + + + A D D ++S +RY+ Sbjct: 2071 SDMATVNINLTDVNDNRPVFSQDVYTAVVSEDAEL--GKTVITVNAEDLDGPSHSHVRYS 2128 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I+ GN F+IDS G++ + LD E R R P ++ QL + RD Sbjct: 2129 IVDGNQGSPFTIDSARGELKVAHQLDRE--RENR----------PKGTSVLQLTVTDRDA 2176 Query: 251 NDNAPRF 257 + N P F Sbjct: 2177 SHNGPPF 2183 Score = 79.0 bits (186), Expect = 2e-12 Identities = 54/178 (30%), Positives = 89/178 (50%), Gaps = 17/178 (9%) Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI-------MEDALVGTSVSQV 603 +T D GVP+ S + V + V+D NDN P+F +++Y + E A+ V +V Sbjct: 1 ITVTDHGVPAKSTSVRVIVQVLDENDNRPLFLEKIYKIKLPEREKPEKERAIKRDPVYRV 60 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV-AIDG 662 A+D D G N I Y ++ D E G F I+P +G++ + K S +D+ + A+D Sbjct: 61 IASDRDDGPNAEISYSIEEGD-ENGKFFIEPKTGLVSSKKF---SSAGEYDILTIKAVDN 116 Query: 663 GTPPQSSTVIVHI----KIEDINDSPPV-FESDCLTFYISENSPIGTTIGEIRAHDPD 715 G P +SS+ +HI K + D+ P+ FE F + E+ P+ +G + D Sbjct: 117 GRPQKSSSCRLHIEWIPKPKLPPDAAPLQFEESPFVFSVMESDPVAHMVGVVATEASD 174 Score = 64.1 bits (149), Expect = 5e-08 Identities = 56/189 (29%), Positives = 93/189 (49%), Gaps = 19/189 (10%) Query: 117 VKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE------DISVTDNPV 170 + TD P S++ + V ++D+NDN P F EK Y + + E + ++ +PV Sbjct: 1 ITVTDHGVPAK---STSVRVIVQVLDENDNRPLFLEKIYKIKLPEREKPEKERAIKRDPV 57 Query: 171 IAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR-LVIRA 229 ++ A+D D G N+ I Y+I G+ +F I+ +G LV + + Y L I+A Sbjct: 58 Y-RVIASDRDDGPNAEISYSIEEGDENGKFFIEPKTG---LVSSKKFSSAGEYDILTIKA 113 Query: 230 QDGGSPSRSNTTQLLI----NIRDVNDNAP-RFYTSLFQESVSENVPIGYSIVRVQAYDA 284 D G P +S++ +L I + D AP +F S F SV E+ P+ + + V + Sbjct: 114 VDNGRPQKSSSCRLHIEWIPKPKLPPDAAPLQFEESPFVFSVMESDPVAHMVGVVATEAS 173 Query: 285 DEGVNAELT 293 D V E+T Sbjct: 174 DVPVWFEIT 182 Score = 56.4 bits (130), Expect = 1e-05 Identities = 56/219 (25%), Positives = 96/219 (43%), Gaps = 9/219 (4%) Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 + + GT ++V I++ D N+ P F ++E++P GT + +I A D DE Sbjct: 181 ITVRWGTKALHHLLLVLIRVIDTNNHRPQFSEKFYEVNVAEDTPPGTEVLQISASDRDE- 239 Query: 718 PNAVVHYSIKGGDDSNSFSL-ETRQGSDKAELVTMVDLDYESPRKK-YELVIRAASPPL- 774 N + + D FSL + R L T LD+E+ +++R P+ Sbjct: 240 KNKLTFTLLSSTD---PFSLRKFRLDPGTGTLYTAETLDHETMHHHILTVMVRDQDIPVK 296 Query: 775 WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRIL 832 N VRV + V D NDNAP ++ +V A D D ++ Y + Sbjct: 297 RNLVRVIVNVDDTNDNAPWFVGAPFSGRVFESAAVGSAVLQVTARDKDKGRNAEVVYSLE 356 Query: 833 SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 SGN AN ++ G++T++ +L+ + + V +D Sbjct: 357 SGNFANTFSIDPKLGTITVAKELDRDSKAQYELTVKASD 395 Score = 52.4 bits (120), Expect = 2e-04 Identities = 48/190 (25%), Positives = 85/190 (44%), Gaps = 20/190 (10%) Query: 227 IRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLF-------QESVSENVPIGYSIVRV 279 I D G P++S + ++++ + D NDN P F ++ ++ E + RV Sbjct: 1 ITVTDHGVPAKSTSVRVIVQVLDENDNRPLFLEKIYKIKLPEREKPEKERAIKRDPVYRV 60 Query: 280 QAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL-VTA 338 A D D+G NAE++Y++ + D G I+P++G V + + +Y +L + A Sbjct: 61 IASDRDDGPNAEISYSIEEGDENGK----FFIEPKTGLVSSK---KFSSAGEYDILTIKA 113 Query: 339 TDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE----VELAEDEPPGTPVVTLTATDAD 394 D G P +S++ P Q+E V + P +V + AT+A Sbjct: 114 VDNGRPQKSSSCRLHIEWIPKPKLPPDAAPLQFEESPFVFSVMESDPVAHMVGVVATEA- 172 Query: 395 EDNRLHYEIT 404 D + +EIT Sbjct: 173 SDVPVWFEIT 182 Score = 51.6 bits (118), Expect = 3e-04 Identities = 49/187 (26%), Positives = 81/187 (43%), Gaps = 22/187 (11%) Query: 336 VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT-------PVVTL 388 +T TD G P +S + F+ Y+++L E E P PV + Sbjct: 1 ITVTDHGVPAKSTSVRVIVQVLDENDNRPLFLEKIYKIKLPEREKPEKERAIKRDPVYRV 60 Query: 389 TATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY-VLTVSATD 445 A+D D+ + + Y I G+ G+F I + G + F Y +LT+ A D Sbjct: 61 IASDRDDGPNAEISYSIEEGDENGKFFIEPKTG-----LVSSKKFSSAGEYDILTIKAVD 115 Query: 446 SGGRSDTAMVQINITDAN------NYAPV-FENAPYTASVFEDAPIGTTVLVVSATDSDV 498 +G ++ +++I + AP+ FE +P+ SV E P+ V VV+ SDV Sbjct: 116 NGRPQKSSSCRLHIEWIPKPKLPPDAAPLQFEESPFVFSVMESDPVAHMVGVVATEASDV 175 Query: 499 GINAQIT 505 + +IT Sbjct: 176 PVWFEIT 182 Score = 47.2 bits (107), Expect = 0.007 Identities = 27/89 (30%), Positives = 45/89 (50%), Gaps = 7/89 (7%) Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT-------IGEIRAHD 713 D G P +S++V V +++ D ND+ P+F + E + + A D Sbjct: 5 DHGVPAKSTSVRVIVQVLDENDNRPLFLEKIYKIKLPEREKPEKERAIKRDPVYRVIASD 64 Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 D+GPNA + YSI+ GD++ F +E + G Sbjct: 65 RDDGPNAEISYSIEEGDENGKFFIEPKTG 93 Score = 43.2 bits (97), Expect = 0.11 Identities = 48/184 (26%), Positives = 78/184 (42%), Gaps = 23/184 (12%) Query: 441 VSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASV-------FEDAPIGTTVLVV 491 ++ TD G +S + V + + D N+ P+F Y + E A V V Sbjct: 1 ITVTDHGVPAKSTSVRVIVQVLDENDNRPLFLEKIYKIKLPEREKPEKERAIKRDPVYRV 60 Query: 492 SATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTV 551 A+D D G NA+I+YS+ N +F I P+TG +++ K +LT+ Sbjct: 61 IASDRDDGPNAEISYSIEEGDEN-------GKFFIEPKTGLVSSKKFSSAGEYD--ILTI 111 Query: 552 TARDGGVPSLSDTTDVEISVVD----VNDNEPV-FKQQLYTANIMEDALVGTSVSQVGAT 606 A D G P S + + I + D P+ F++ + ++ME V V V Sbjct: 112 KAVDNGRPQKSSSCRLHIEWIPKPKLPPDAAPLQFEESPFVFSVMESDPVAHMVGVVATE 171 Query: 607 DADV 610 +DV Sbjct: 172 ASDV 175 >UniRef50_UPI0000E46DFB Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 3342 Score = 398 bits (979), Expect = e-108 Identities = 290/880 (32%), Positives = 425/880 (48%), Gaps = 68/880 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 IN+LD ND++P F+ +++E + T+ ATD D G N + YTI Sbjct: 1434 INILDQNDNTPDFDQDLIYLTLQENVGINHVLWTVSATDADSGANGLIRYTI-------- 1485 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 QD F +D +G L T ++D E + ++++A DQA VS R Sbjct: 1486 -------------LTEQDFFAVDEYTGTLRTIQNVDHEINHVFLLVIQAQDQAINVSARR 1532 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 ++T+T+ V I D NDN P F ++ T V ED V N + I ATD D G N + Y Sbjct: 1533 AATSTVEVRIYDSNDNNPVFVSRSST-DVMEDEPVGFN--VIHIIATDEDSGENGRVGYT 1589 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I GN +FS+D+++G +++ +LD+E R Y LVI A D G+ R T L I + DV Sbjct: 1590 ITSGNEDGKFSLDAVTGLLTIAHSLDHEHKRDYELVILATDHGTVQRMATQTLTIRVIDV 1649 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 ND PRF S++ +VSE+ G + V A D D GVN +TY + ++ G Sbjct: 1650 NDQPPRFEQSIYVMNVSESQAPGTYVGMVVAIDGDSGVNGRITYELPEEIARG----MFR 1705 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I+ +G + T LDRE + Y + V A DG P R AT F P Sbjct: 1706 INATTGEIRTKAILDREQRDSYVVTVYAMDGAFPARYDMATVLVYVMDVNDNNPTFAPPT 1765 Query: 371 YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 +++ L E++ PG + ATDADE + L Y ITGG+ + FSI G + TV Sbjct: 1766 FDITLPENQSPGV-IHNAIATDADEGPNGDLIYSITGGDPKNAFSINQSTG-AIFTVG-A 1822 Query: 429 LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD + E Y LT++ATD G RS T +++ +TD N+ PVF + Y S+ E I Sbjct: 1823 LDREDEATYTLTITATDQGTSPRSGTTTIRVTVTDLNDNDPVFGSMSYYKSIPESTAINA 1882 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 T+L V ATD D G+N + Y+L N + F I+P+ G ITT D E + Sbjct: 1883 TILTVVATDDDEGLNGDVYYTL----DNTTIG----LFSIDPEHGEITTTGKFDYEKETR 1934 Query: 547 YLLTVTARDGGV-PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 Y VTA D GV S+ V I + DVNDN PVFK AN+ +DA T V+ V A Sbjct: 1935 YTFQVTATDSGVFGPRSERVQVIIDISDVNDNAPVFKTIPIRANVTQDASSNTFVANVEA 1994 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 D D G+NG ++Y ++ SF ID +GVI T K+L+ ++ H L+ +A D G+P Sbjct: 1995 DDKDSGVNGEVNYRF---TQQSSSFAIDTVTGVI-TTKSLNPGTLFYH-LEVMAFDLGSP 2049 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 SS IV + + F SE + G + + A PD + + YS Sbjct: 2050 SLSSNGIVEVWVGTSGSGGLQFGQQTYLVQPSEAADNGDVVLSLSAFLPDGSSSNDIVYS 2109 Query: 726 IKGGDDSNSFSLETRQGSDKAELVT-MVDLDYESPRKKYELVIRAA-----SPPLWNDVR 779 + G+++ +F ++ + G +V LDYE+ + LV A S P++ Sbjct: 2110 LVSGNENGAFGIQVQAGGSAILVVADTTKLDYET-QPNIRLVAEAMRTPENSSPMYGYAT 2168 Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-----FGRVPAYDAD--VTDKLQYRIL 832 V++ +TD NDNAP Q + + Y+ P +V A DAD + Y + Sbjct: 2169 VQVELTDANDNAP-----QFVQDRYQSRVWEVPNSDIYVTQVSATDADEGTNGAIYYEVT 2223 Query: 833 SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 SGN N ++ TG +T + L+ + + V DG Sbjct: 2224 SGNTDNAFAIDHVTGIVTTAKSLDYEIEDSYVLTVVARDG 2263 Score = 343 bits (844), Expect = 3e-92 Identities = 284/896 (31%), Positives = 418/896 (46%), Gaps = 68/896 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V+D ND++P F ++ ++ E S G + ATD D G N ++ Y+I T Sbjct: 1749 VYVMDVNDNNPTFAPPTFDITLPENQSPGV-IHNAIATDADEGPNGDLIYSI---TGG-- 1802 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +P++A F I+ +GA+ T +LDRE A YT+ + ATDQ + S R Sbjct: 1803 DPKNA--------------FSINQSTGAIFTVGALDREDEATYTLTITATDQGT--SPR- 1845 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S T TI V + D NDN P F +Y S+ E ++ N I + ATD D G N + Y Sbjct: 1846 SGTTTIRVTVTDLNDNDPVFGSMSYYKSIPESTAI--NATILTVVATDDDEGLNGDVYYT 1903 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS-PSRSNTTQLLINIRD 249 + T FSID G+++ DYE+ Y + A D G RS Q++I+I D Sbjct: 1904 L-DNTTIGLFSIDPEHGEITTTGKFDYEKETRYTFQVTATDSGVFGPRSERVQVIIDISD 1962 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 VNDNAP F T + +V+++ + V+A D D GVN E+ Y T + + Sbjct: 1963 VNDNAPVFKTIPIRANVTQDASSNTFVANVEADDKDSGVNGEVNYRFTQQSSS------F 2016 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 ID +G V T+ L+ T Y L V A D G P S+ F Sbjct: 2017 AIDTVTG-VITTKSLNPGTLF-YHLEVMAFDLGSPSLSSNGIVEVWVGTSGSGGLQFGQQ 2074 Query: 370 QYEVELAEDEPPGTPVVTLTA--TDADEDNRLHYEITGGNTRGRFSITSQ-NGRGLITVA 426 Y V+ +E G V++L+A D N + Y + GN G F I Q G ++ VA Sbjct: 2075 TYLVQPSEAADNGDVVLSLSAFLPDGSSSNDIVYSLVSGNENGAFGIQVQAGGSAILVVA 2134 Query: 427 QP--LDFKQERRYVLTVSATDSGGRSDT----AMVQINITDANNYAPVFENAPYTASVFE 480 LD++ + L A + S A VQ+ +TDAN+ AP F Y + V+E Sbjct: 2135 DTTKLDYETQPNIRLVAEAMRTPENSSPMYGYATVQVELTDANDNAPQFVQDRYQSRVWE 2194 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 V VSATD+D G N I Y ++S + D F I+ TG +TT K LD Sbjct: 2195 VPNSDIYVTQVSATDADEGTNGAIYYEVTS-------GNTDNAFAIDHVTGIVTTAKSLD 2247 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 E Y+LTV ARDGG P L+ T + I +VDVNDN+PVF Q + ++ ED VG SV Sbjct: 2248 YEIEDSYVLTVVARDGGSPQLTGTATMRIGIVDVNDNQPVFVQ-MDPVSVSEDLGVGLSV 2306 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 + V ATD+D N I Y G F ID SG+I ++LDRE+ + L+ A Sbjct: 2307 TTVTATDSDT--NPNIQYSFTSTGNPGGYFAIDQYSGIITLARSLDRETQDGYTLELEAT 2364 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 D ++T+ + + + D ND+ PVF + + E + + + A D D G NA Sbjct: 2365 D---TEYTTTMTLEVIVTDENDNAPVFRQESYQVTLPELTQPNVAVVAVNASDKDIGLNA 2421 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRV 780 + YS D SF ++ G V + D E+ + Y + +P L V V Sbjct: 2422 ELTYSFV--DSHPSFYIDPITGVIFTNQVIEFN-DVETTIQLYVTATDSGAPALSEFVTV 2478 Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVT---DKLQYRILSGNN 836 I +TDVN+ +PV + I + + +G V A D D++ K+ Y I SGN+ Sbjct: 2479 RIEITDVNNQSPVFVE-DIYSASVSENVSLGHHVITVVAEDMDLSPENSKINYFIESGND 2537 Query: 837 ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG---VNEIKAMMQLSVRLITE 889 ++ GS+T+ +L+ T+ + D VN A + + V I + Sbjct: 2538 QGKFKIDANDGSITVLERLDREATDTYTLIIGAVDNGEPVNNATAEVVIEVEDIND 2593 Score = 334 bits (822), Expect = 2e-89 Identities = 263/879 (29%), Positives = 412/879 (46%), Gaps = 66/879 (7%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 + I V+D ND+ P F Q S+ E G+++ A D D G N V Y + Sbjct: 911 VQVNITVIDVNDNVPQFMAQTARTSIPESTGIGSSIYVATAMDLDSGDNGLVRYRL---- 966 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 T NP + FRI +G ++ + + V ++A D P Sbjct: 967 --TSNPGNT--------------FRIVEATGEIILNKEVSYNDQLSFEVDIQAYDAGEP- 1009 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 L + T+ V I+D NDN P F+ Y VS+ E++ ++ PV+ +++ATD D GAN+ Sbjct: 1010 --SLEGSLTLTVIILDVNDNGPVFTMGFYPVSILENLPIS-TPVV-QVEATDNDRGANAL 1065 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 I Y + N F++ G + + LD E ++ L I A D GSP ++++ + + Sbjct: 1066 ITYTLTPNNDSPYFAVFPREGWLYTRQVLDRELKSTFTLTIMASDSGSPPQNSSATVQVT 1125 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + D NDNAP F + ++EN+P G + RV+A D D G N ++TYT++ +G+ Sbjct: 1126 VVDANDNAPHFTKKSYHFHINENLPAGTEVDRVEAVDPDLGPNGQVTYTLSP---SGD-- 1180 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 TID G + T+ LDRE Y+L++ A DGG+P S++AT F Sbjct: 1181 --FTID-EEGVIRTTHPLDREAAYSYRLIIRAVDGGNPALSSSATVYINVNDLNDNAPVF 1237 Query: 367 MPGQ-YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV 425 + Y+ + E++P G V + ATD D + + ++ +F I S G+I+ Sbjct: 1238 SQDRTYQASVREEQPAGEFVAWIIATDTDSGVLGNISYSLIDSSPKFIIDSS---GVIST 1294 Query: 426 AQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 A +D + E Y LTV A D G TA V++ I D N+ P+ + Y + E+ Sbjct: 1295 AAAIDREDESYYTLTVLAQDGGNPPMQATASVRVRILDLNDNVPIAAMSAYIFTADENIQ 1354 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 T V VVSA+D DVG N +I Y ++ + + +N +G + +++D E Sbjct: 1355 PPTVVGVVSASDMDVGDNGKIYYYITE-------GNDFDVWDVNHSSGEVYNVRVVDYEM 1407 Query: 544 MSGYLLTVTARDGGVPSLSDTT-DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 + Y LT+ A+D VP T+ V I+++D NDN P F Q L + E+ + + Sbjct: 1408 AAHYTLTIIAQDNNVPQTHSTSISVTINILDQNDNTPDFDQDLIYLTLQENVGINHVLWT 1467 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 V ATDAD G NG I Y + E+ F +D +G +RT + +D E L A D Sbjct: 1468 VSATDADSGANGLIRYTI---LTEQDFFAVDEYTGTLRTIQNVDHEINHVFLLVIQAQDQ 1524 Query: 663 G---TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 + +++T V ++I D ND+ PVF S T + E+ P+G + I A D D G N Sbjct: 1525 AINVSARRAATSTVEVRIYDSNDNNPVFVSRSST-DVMEDEPVGFNVIHIIATDEDSGEN 1583 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRAASPPLWNDV 778 V Y+I G++ FSL+ G L+T+ LD+E ++ YELVI A + Sbjct: 1584 GRVGYTITSGNEDGKFSLDAVTG-----LLTIAHSLDHEH-KRDYELVILATDHGTVQRM 1637 Query: 779 RVEIL---VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILS 833 + L V DVND P + + N + P G V A D D V ++ Y + Sbjct: 1638 ATQTLTIRVIDVNDQPPRFEQSIYVMNVSESQAPGTYVGMVVAIDGDSGVNGRITYELPE 1697 Query: 834 GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 + +N TTG + L+ + V DG Sbjct: 1698 EIARGMFRINATTGEIRTKAILDREQRDSYVVTVYAMDG 1736 Score = 333 bits (819), Expect = 3e-89 Identities = 270/895 (30%), Positives = 411/895 (45%), Gaps = 65/895 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ V D ND+ PVF Y S+ E + T+LT+ ATD D G N +V YT++ T Sbjct: 1852 RVTVTDLNDNDPVFGSMSYYKSIPESTAINATILTVVATDDDEGLNGDVYYTLDNTTI-- 1909 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 +F ID G + T D EK RYT V ATD S V Sbjct: 1910 ------------------GLFSIDPEHGEITTTGKFDYEKETRYTFQVTATD--SGVFGP 1949 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S + ++I D NDN P F +V +D S N +A ++A D D G N + Y Sbjct: 1950 RSERVQVIIDISDVNDNAPVFKTIPIRANVTQDAS--SNTFVANVEADDKDSGVNGEVNY 2007 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 F+ID+++G V K+L+ Y L + A D GSPS S+ + + + Sbjct: 2008 RFT--QQSSSFAIDTVTG-VITTKSLN-PGTLFYHLEVMAFDLGSPSLSSNGIVEVWVGT 2063 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 +F + SE G ++ + A+ D + ++ Y++ + G + + Sbjct: 2064 SGSGGLQFGQQTYLVQPSEAADNGDVVLSLSAFLPDGSSSNDIVYSLVSGNENGAFGIQV 2123 Query: 310 TIDPRSGWVYT-SGQLDRETQAKYQLLVTA--TDGGDPPRSATATXXXXXXXXXXXXXXF 366 + V + +LD ETQ +L+ A T P AT F Sbjct: 2124 QAGGSAILVVADTTKLDYETQPNIRLVAEAMRTPENSSPMYGYATVQVELTDANDNAPQF 2183 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLIT 424 + +Y+ + E V ++ATDADE + ++YE+T GNT F+I + G++T Sbjct: 2184 VQDRYQSRVWEVPNSDIYVTQVSATDADEGTNGAIYYEVTSGNTDNAFAI--DHVTGIVT 2241 Query: 425 VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 A+ LD++ E YVLTV A D G + TA ++I I D N+ PVF SV ED Sbjct: 2242 TAKSLDYEIEDSYVLTVVARDGGSPQLTGTATMRIGIVDVNDNQPVFVQMD-PVSVSEDL 2300 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 +G +V V+ATDSD N I YS +S + F I+ +G IT + LDRE Sbjct: 2301 GVGLSVTTVTATDSDT--NPNIQYSFTS------TGNPGGYFAIDQYSGIITLARSLDRE 2352 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 T GY L + A D + T +E+ V D NDN PVF+Q+ Y + E +V Sbjct: 2353 TQDGYTLELEATD---TEYTTTMTLEVIVTDENDNAPVFRQESYQVTLPELTQPNVAVVA 2409 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV-ATHDLKAVAID 661 V A+D D+GLN + Y SF IDP +GVI TN+ ++ V T L A D Sbjct: 2410 VNASDKDIGLNAELTYSFVD---SHPSFYIDPITGVIFTNQVIEFNDVETTIQLYVTATD 2466 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP-NA 720 G P S V V I+I D+N+ PVF D + +SEN +G + + A D D P N+ Sbjct: 2467 SGAPALSEFVTVRIEITDVNNQSPVFVEDIYSASVSENVSLGHHVITVVAEDMDLSPENS 2526 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA--SPPLWN-D 777 ++Y I+ G+D F ++ GS + + LD E+ Y L+I A P+ N Sbjct: 2527 KINYFIESGNDQGKFKIDANDGS----ITVLERLDREA-TDTYTLIIGAVDNGEPVNNAT 2581 Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGN 835 V I V D+ND++P+ Q ++ V A D D+ +++Y I+SG Sbjct: 2582 AEVVIEVEDINDHSPIFDHVQYEGRIAENATASTYILTVHATDRDIGYNGEVEYSIISGT 2641 Query: 836 NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITE 889 ++L ++ +G++T+ +L+ + V +D G+ A + L IT+ Sbjct: 2642 YSDLFAIDVVSGAVTVRGELDREEVERVEFTVQASDRGMENQLASVVLVTITITD 2696 Score = 332 bits (816), Expect = 8e-89 Identities = 251/744 (33%), Positives = 358/744 (48%), Gaps = 41/744 (5%) Query: 134 ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV-IAKIKATDADVGANSAIRYAII 192 AT+ V + D NDN PQF + Y V E V ++ + + ++ ATDAD G N AI Y + Sbjct: 2167 ATVQVELTDANDNAPQFVQDRYQSRVWE---VPNSDIYVTQVSATDADEGTNGAIYYEVT 2223 Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252 GNT F+ID ++G V+ K+LDYE SY L + A+DGGSP + T + I I DVND Sbjct: 2224 SGNTDNAFAIDHVTGIVTTAKSLDYEIEDSYVLTVVARDGGSPQLTGTATMRIGIVDVND 2283 Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312 N P F + SVSE++ +G S+ V A D+D N + ++T TGN ID Sbjct: 2284 NQPVF-VQMDPVSVSEDLGVGLSVTTVTATDSDTNPNIQYSFTS-----TGNPGGYFAID 2337 Query: 313 PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE 372 SG + + LDRETQ Y L + AT D + T T F Y+ Sbjct: 2338 QYSGIITLARSLDRETQDGYTLELEAT---DTEYTTTMTLEVIVTDENDNAPVFRQESYQ 2394 Query: 373 VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432 V L E P VV + A +D+D L+ E+T S G+I Q ++F Sbjct: 2395 VTLPELTQPNVAVVAVNA--SDKDIGLNAELTYSFVDSHPSFYIDPITGVIFTNQVIEFN 2452 Query: 433 Q-ERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 E L V+ATDSG S+ V+I ITD NN +PVF Y+ASV E+ +G V+ Sbjct: 2453 DVETTIQLYVTATDSGAPALSEFVTVRIEITDVNNQSPVFVEDIYSASVSENVSLGHHVI 2512 Query: 490 VVSATDSDVG-INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 V A D D+ N++I Y + S + +F I+ G+IT + LDRE Y Sbjct: 2513 TVVAEDMDLSPENSKINYFIES-------GNDQGKFKIDANDGSITVLERLDREATDTYT 2565 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 L + A D G P + T +V I V D+ND+ P+F Y I E+A T + V ATD Sbjct: 2566 LIIGAVDNGEPVNNATAEVVIEVEDINDHSPIFDHVQYEGRIAENATASTYILTVHATDR 2625 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ- 667 D+G NG + Y + + F ID SG + LDRE V + A D G Q Sbjct: 2626 DIGYNGEVEYSIISGTYSD-LFAIDVVSGAVTVRGELDREEVERVEFTVQASDRGMENQL 2684 Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 +S V+V I I D N+ PP F F + EN P+ T + A D D G + YSI+ Sbjct: 2685 ASVVLVTITITDFNEFPPYFPQLFYHFLVPENMPVETYVFTAGALDNDAGEYGELTYSIR 2744 Query: 728 GGDDSNS---FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEIL 783 G SN F+++ G E+ T DYES Y V++A + L ++ E+ Sbjct: 2745 GLGPSNGDDYFTIDPVTG----EVFTAAVFDYES-ANSYRFVVQAQDTGGLSISIQTEVN 2799 Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDKLQYRILSGNNANLILL 842 +T V++ P+ D + F D G + G+V A DAD + ++ + Sbjct: 2800 ITSVDEFPPMFNDQEYYF-EIGDGADAGDYVGQVTATDADGGE--DGVVIYSLTHEFFYI 2856 Query: 843 NETTGSMTLSPQLNTNVPKLATME 866 TTG + ++ LN++ K +E Sbjct: 2857 EATTGIIKVAKPLNSSARKRRGLE 2880 Score = 324 bits (797), Expect = 2e-86 Identities = 262/890 (29%), Positives = 409/890 (45%), Gaps = 64/890 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+ P+F++ Y A++ E + GT V + ATD D G NA++ Y I Sbjct: 493 IAVTDVNDNPPIFDLPLYHATIIEASEPGTPVKQVHATDADEGVNAQIIYRI-------- 544 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +PE D F I+ SG + T +DRE+ + V A+D+ +S L Sbjct: 545 SPEGTDYS---------DWFEINPMSGLVTTLQKVDREETGSVFLTVIASDEGE-IS--L 592 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SS+ I++ I D NDN P F +Y S+ E+ + ++ ATD D G+ + Y+ Sbjct: 593 SSSVIINITITDVNDNQPVFFPGSYNASILEEQEIP--YCFLQVNATDPDEGSAGQVTYS 650 Query: 191 IIGG--NTQMQFSIDSLSGDVSLVKTLDYEQ-VRSYRLVIRAQDGGSPSRSNTTQLLINI 247 T QFSI+ L+GD+ ++ LD + Y ++A DGG +++ + Sbjct: 651 PSTDLVPTPSQFSINPLTGDLCVISRLDRDAGQEEYNFAVKATDGGGLMSHAFVRVI--L 708 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 D+NDN P F + ++ + + +G + V A D D +TYT+ D + N D Sbjct: 709 EDINDNVPVFTSLNYRGHIEYDAALGTEVKLVVAEDRDAREFGRVTYTI---DSSTN-DG 764 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 I+ +G + G LD Y L V ATDGG + A F Sbjct: 765 TFAINQTTGLITLVGSLDWVQHPVYTLEVIATDGGGRTSANHAQVTITVAGPDTSPPEFE 824 Query: 368 PGQYEVELAEDEPPG-TPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 Y + E+ V D + Y +T G+ F I + +G + T Sbjct: 825 SSSYAFSVQENAAQVLVGAVKAGHIDPGITFPITYTLTSGDPNDFFRINTTSGE-IFTRG 883 Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPI 484 D +Q+ ++T+ A SG VQ+NIT D N+ P F S+ E I Sbjct: 884 SGPDHEQQAFVLITIQAA-SGMPPTYDDVQVNITVIDVNDNVPQFMAQTARTSIPESTGI 942 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 G+++ V +A D D G N + Y L+S N F I TG I NK + Sbjct: 943 GSSIYVATAMDLDSGDNGLVRYRLTSNPGN--------TFRIVEATGEIILNKEVSYNDQ 994 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 + + + A D G PSL + + + ++DVNDN PVF Y +I+E+ + T V QV Sbjct: 995 LSFEVDIQAYDAGEPSLEGSLTLTVIILDVNDNGPVFTMGFYPVSILENLPISTPVVQVE 1054 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 ATD D G N I Y L P + + F + P G + T + LDRE +T L +A D G+ Sbjct: 1055 ATDNDRGANALITYTLTP-NNDSPYFAVFPREGWLYTRQVLDRELKSTFTLTIMASDSGS 1113 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 PPQ+S+ V + + D ND+ P F F+I+EN P GT + + A DPD GPN V Y Sbjct: 1114 PPQNSSATVQVTVVDANDNAPHFTKKSYHFHINENLPAGTEVDRVEAVDPDLGPNGQVTY 1173 Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVE 781 ++ S F+++ ++ + T LD E+ Y L+IRA +P L + V Sbjct: 1174 TL---SPSGDFTID-----EEGVIRTTHPLDREA-AYSYRLIIRAVDGGNPALSSSATVY 1224 Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDAD--VTDKLQYRILSGNNAN 838 I V D+NDNAPV + + ++ P G F + A D D V + Y ++ + Sbjct: 1225 INVNDLNDNAPVFSQDRTYQASVREEQPAGEFVAWIIATDTDSGVLGNISYSLIDSSPKF 1284 Query: 839 LILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN-EIKAMMQLSVRLI 887 +I +++G ++ + ++ T+ V DG N ++A + VR++ Sbjct: 1285 II---DSSGVISTAAAIDREDESYYTLTVLAQDGGNPPMQATASVRVRIL 1331 Score = 320 bits (787), Expect = 3e-85 Identities = 259/877 (29%), Positives = 403/877 (45%), Gaps = 69/877 (7%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 D ND+ PVF Y + A+ GT V + A D+D + V YTI+ T D Sbjct: 710 DINDNVPVFTSLNYRGHIEYDAALGTEVKLVVAEDRDAREFGRVTYTIDSSTND------ 763 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134 F I+ +G + SLD + YT+ V ATD S ++ A Sbjct: 764 -------------GTFAINQTTGLITLVGSLDWVQHPVYTLEVIATDGGGRTS---ANHA 807 Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194 + + + + + P+F +Y SV E+ + ++ +KA D G I Y + G Sbjct: 808 QVTITVAGPDTSPPEFESSSYAFSVQENAAQV---LVGAVKAGHIDPGITFPITYTLTSG 864 Query: 195 NTQMQFSIDSLSGDV-SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDN 253 + F I++ SG++ + D+EQ + I+A G P+ + Q+ I + DVNDN Sbjct: 865 DPNDFFRINTTSGEIFTRGSGPDHEQQAFVLITIQAASGMPPTYDDV-QVNITVIDVNDN 923 Query: 254 APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313 P+F + S+ E+ IG SI A D D G N + Y +T GN I Sbjct: 924 VPQFMAQTARTSIPESTGIGSSIYVATAMDLDSGDNGLVRYRLTSN--PGNT---FRIVE 978 Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373 +G + + ++ Q +++ + A D G+P + T F G Y V Sbjct: 979 ATGEIILNKEVSYNDQLSFEVDIQAYDAGEPSLEGSLTLTVIILDVNDNGPVFTMGFYPV 1038 Query: 374 ELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431 + E+ P TPVV + ATD D + + Y +T N F++ + G + Q LD Sbjct: 1039 SILENLPISTPVVQVEATDNDRGANALITYTLTPNNDSPYFAVFPR--EGWLYTRQVLDR 1096 Query: 432 KQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 + + + LT+ A+DSG ++ +A VQ+ + DAN+ AP F Y + E+ P GT V Sbjct: 1097 ELKSTFTLTIMASDSGSPPQNSSATVQVTVVDANDNAPHFTKKSYHFHINENLPAGTEVD 1156 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 V A D D+G N Q+TY+LS F I+ + G I T LDRE Y L Sbjct: 1157 RVEAVDPDLGPNGQVTYTLSP----------SGDFTID-EEGVIRTTHPLDREAAYSYRL 1205 Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ-QLYTANIMEDALVGTSVSQVGATDA 608 + A DGG P+LS + V I+V D+NDN PVF Q + Y A++ E+ G V+ + ATD Sbjct: 1206 IIRAVDGGNPALSSSATVYINVNDLNDNAPVFSQDRTYQASVREEQPAGEFVAWIIATDT 1265 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 D G+ G I Y L + F+ID +SGVI T A+DRE + + L +A DGG PP Sbjct: 1266 DSGVLGNISYSLIDSSPK---FIID-SSGVISTAAAIDREDESYYTLTVLAQDGGNPPMQ 1321 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 +T V ++I D+ND+ P+ F EN T +G + A D D G N ++Y I Sbjct: 1322 ATASVRVRILDLNDNVPIAAMSAYIFTADENIQPPTVVGVVSASDMDVGDNGKIYYYITE 1381 Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWN-DVRVEILV 784 G+D + + + G E+ + +DYE Y L I A P + + V I + Sbjct: 1382 GNDFDVWDVNHSSG----EVYNVRVVDYEM-AAHYTLTIIAQDNNVPQTHSTSISVTINI 1436 Query: 785 TDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILSGNNANLIL 841 D NDN P D +I+ ++ + V A DAD ++Y IL+ + Sbjct: 1437 LDQNDNTPDF-DQDLIYLTLQENVGINHVLWTVSATDADSGANGLIRYTILT--EQDFFA 1493 Query: 842 LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKA 878 ++E TG++ ++ + + + + D + A Sbjct: 1494 VDEYTGTLRTIQNVDHEINHVFLLVIQAQDQAINVSA 1530 Score = 309 bits (759), Expect = 6e-82 Identities = 253/794 (31%), Positives = 374/794 (47%), Gaps = 57/794 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V+D ND P FE Y +V E + GT V + A D D G N + Y + Sbjct: 1644 IRVIDVNDQPPRFEQSIYVMNVSESQAPGTYVGMVVAIDGDSGVNGRITYEL-------- 1695 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 PE+ + +FRI+ +G + T+A LDRE+ Y V V A D A P Sbjct: 1696 -PEE----------IARGMFRINATTGEIRTKAILDREQRDSYVVTVYAMDGAFPAR--- 1741 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 AT+ V ++D NDN P F+ T+ +++ E+ S VI ATDAD G N + Y+ Sbjct: 1742 YDMATVLVYVMDVNDNNPTFAPPTFDITLPENQS---PGVIHNAIATDADEGPNGDLIYS 1798 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I GG+ + FSI+ +G + V LD E +Y L I A D G+ RS TT + + + D+ Sbjct: 1799 ITGGDPKNAFSINQSTGAIFTVGALDREDEATYTLTITATDQGTSPRSGTTTIRVTVTDL 1858 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F + + +S+ E+ I +I+ V A D DEG+N ++ YT+ D T + L + Sbjct: 1859 NDNDPVFGSMSYYKSIPESTAINATILTVVATDDDEGLNGDVYYTL---DNT-TIGL-FS 1913 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPPRSATATXXXXXXXXXXXXXXFMPG 369 IDP G + T+G+ D E + +Y VTATD G PRS F Sbjct: 1914 IDPEHGEITTTGKFDYEKETRYTFQVTATDSGVFGPRSERVQVIIDISDVNDNAPVFKTI 1973 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 + +D T V + A D+D+ ++ E+ T+ S G+IT + L Sbjct: 1974 PIRANVTQDASSNTFVANVEAD--DKDSGVNGEVNYRFTQQSSSFAIDTVTGVIT-TKSL 2030 Query: 430 DFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 + Y L V A D G S +V++ + + + F Y E A G Sbjct: 2031 N-PGTLFYHLEVMAFDLGSPSLSSNGIVEVWVGTSGSGGLQFGQQTYLVQPSEAADNGDV 2089 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 VL +SA D + I YSL S N A Q A TT LD ET Sbjct: 2090 VLSLSAFLPDGSSSNDIVYSLVSGNENGAFGIQVQAGGSAILVVADTTK--LDYETQPNI 2147 Query: 548 LLTVTAR---DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 L A + P T V++ + D NDN P F Q Y + + E V+QV Sbjct: 2148 RLVAEAMRTPENSSPMYGYAT-VQVELTDANDNAPQFVQDRYQSRVWEVPNSDIYVTQVS 2206 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 ATDAD G NG I+YE+ + +F ID +G++ T K+LD E ++ L VA DGG+ Sbjct: 2207 ATDADEGTNGAIYYEV-TSGNTDNAFAIDHVTGIVTTAKSLDYEIEDSYVLTVVARDGGS 2265 Query: 665 PPQSSTVIVHIKIEDINDSPPVF-ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 P + T + I I D+ND+ PVF + D ++ +SE+ +G ++ + A D D PN + Sbjct: 2266 PQLTGTATMRIGIVDVNDNQPVFVQMDPVS--VSEDLGVGLSVTTVTATDSDTNPN--IQ 2321 Query: 724 YSIKG-GDDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRAASPPLWNDVRVE 781 YS G+ F+++ G ++T+ LD E+ + Y L + A + +E Sbjct: 2322 YSFTSTGNPGGYFAIDQYSG-----IITLARSLDRET-QDGYTLELEATDTEYTTTMTLE 2375 Query: 782 ILVTDVNDNAPVMK 795 ++VTD NDNAPV + Sbjct: 2376 VIVTDENDNAPVFR 2389 Score = 299 bits (733), Expect = 9e-79 Identities = 238/791 (30%), Positives = 371/791 (46%), Gaps = 64/791 (8%) Query: 90 FRIDGRSGALLTRASLDREKVA--RYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 F I+ +G + T A LDRE + ++V A + + + TI +N D NDN Sbjct: 122 FMIESDTGIITTGAVLDRETAPDQEFVIIVFAGEMFTAL------VVTIRLN--DTNDNN 173 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIK---ATDADVGANSAIRYAIIGGNTQMQFSID- 203 P FS+ T V E + P + KI ATDAD G N Y I+GGN F +D Sbjct: 174 PIFSQDNRTFEVTEAVQ----PYMTKINGVTATDADEGINGIQGYRIVGGNIDNTFDLDV 229 Query: 204 -----SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY 258 + D+ + KTLD E + Y L+I A DGG P + T + I + DVNDN+P F Sbjct: 230 RVRETGVYMDIVVNKTLDRETISMYTLIIEAYDGGDPRLTANTTVNIKVTDVNDNSPVFT 289 Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV 318 + F +++E+ P+ ++++V A D DEG+N E+ + + D IDP SG V Sbjct: 290 LTSFTATINESAPVNTTVLQVTASDEDEGLNGEVVFNLQRDDGF------FRIDPASGIV 343 Query: 319 YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX-----XXXXXFMPGQYEV 373 Y + L+ E + LV A D +PP S+ F+P Sbjct: 344 YLNKVLNYEDAQAHDFLVIAQDKAEPPMSSQPAYVSIMVININEKPPSLEVLFLPDGGAS 403 Query: 374 ELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRG----LITVAQ 427 +++E T + ++ TD D+ + ITGG G+F + + + + T A Sbjct: 404 QVSEAAVADTTLARISVTDPDDGVLTNVSMTITGG--AGQFDLQKNSNQVYFLIVATTAS 461 Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIG 485 D ++ Y +++ ATD G A + I +TD N+ P+F+ Y A++ E + G Sbjct: 462 SFDREEVASYDISIRATDHGSPPQHAEENLTIAVTDVNDNPPIFDLPLYHATIIEASEPG 521 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 T V V ATD+D G+NAQI Y +S E ++ + F INP +G +TT + +DRE Sbjct: 522 TPVKQVHATDADEGVNAQIIYRISPEGTD-----YSDWFEINPMSGLVTTLQKVDREETG 576 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 LTV A D G SLS + + I++ DVNDN+PVF Y A+I+E+ + QV A Sbjct: 577 SVFLTVIASDEGEISLSSSVIINITITDVNDNQPVFFPGSYNASILEEQEIPYCFLQVNA 636 Query: 606 TDADVGLNGRIHYELDPK-DREEGSFVIDPASGVIRTNKALDRES-VATHDLKAVAIDGG 663 TD D G G++ Y F I+P +G + LDR++ ++ A DGG Sbjct: 637 TDPDEGSAGQVTYSPSTDLVPTPSQFSINPLTGDLCVISRLDRDAGQEEYNFAVKATDGG 696 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 S V + +EDIND+ PVF S +I ++ +GT + + A D D V Sbjct: 697 --GLMSHAFVRVILEDINDNVPVFTSLNYRGHIEYDAALGTEVKLVVAEDRDAREFGRVT 754 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMV-DLDY-ESPRKKYELVIR-AASPPLWNDVRV 780 Y+I + +F++ G L+T+V LD+ + P E++ N +V Sbjct: 755 YTIDSSTNDGTFAINQTTG-----LITLVGSLDWVQHPVYTLEVIATDGGGRTSANHAQV 809 Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA--YDADVTDKLQYRILSGNNAN 838 I V + + P + F+ ++ V G V A D +T + Y + SG+ + Sbjct: 810 TITVAGPDTSPPEFESSSYAFSVQENAAQV-LVGAVKAGHIDPGITFPITYTLTSGDPND 868 Query: 839 LILLNETTGSM 849 +N T+G + Sbjct: 869 FFRINTTSGEI 879 Score = 277 bits (680), Expect = 2e-72 Identities = 239/797 (29%), Positives = 355/797 (44%), Gaps = 56/797 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+SPVF + + A++ E A TTVL + A+D+D G N EV + L Sbjct: 276 IKVTDVNDNSPVFTLTSFTATINESAPVNTTVLQVTASDEDEGLNGEVVF--------NL 327 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +D FRID SG + L+ E + LV A D+A P Sbjct: 328 QRDDG-------------FFRIDPASGIVYLNKVLNYEDAQAHDFLVIAQDKAEPPMS-- 372 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYT---VSVDEDISVTDNPVIAKIKATDADVGANSAI 187 S A + + +I+ N+ P S + +V D +A+I TD D G + + Sbjct: 373 SQPAYVSIMVININEKPPSLEVLFLPDGGASQVSEAAVADT-TLARISVTDPDDGVLTNV 431 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKT----LDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 I GG Q +S +V T D E+V SY + IRA D GSP + L Sbjct: 432 SMTITGGAGQFDLQKNSNQVYFLIVATTASSFDREEVASYDISIRATDHGSPPQHAEENL 491 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 I + DVNDN P F L+ ++ E G + +V A DADEGVNA++ Y ++ + T Sbjct: 492 TIAVTDVNDNPPIFDLPLYHATIIEASEPGTPVKQVHATDADEGVNAQIIYRISPEG-TD 550 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 D I+P SG V T ++DRE L V A+D G+ S++ Sbjct: 551 YSDW-FEINPMSGLVTTLQKVDREETGSVFLTVIASDEGEISLSSSVIINITITDVNDNQ 609 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGG--NTRGRFSITSQNG 419 F PG Y + E++ + + ATD DE + ++ Y + T +FSI G Sbjct: 610 PVFFPGSYNASILEEQEIPYCFLQVNATDPDEGSAGQVTYSPSTDLVPTPSQFSINPLTG 669 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479 + D QE Y V ATD GG A V++ + D N+ PVF + Y + Sbjct: 670 DLCVISRLDRDAGQE-EYNFAVKATDGGGLMSHAFVRVILEDINDNVPVFTSLNYRGHIE 728 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 DA +GT V +V A D D ++TY++ S + +D F IN TG IT L Sbjct: 729 YDAALGTEVKLVVAEDRDAREFGRVTYTIDS-------STNDGTFAINQTTGLITLVGSL 781 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 D Y L V A DGG + ++ V I+V + + P F+ Y ++ E+A Sbjct: 782 DWVQHPVYTLEVIATDGGGRTSANHAQVTITVAGPDTSPPEFESSSYAFSVQENA-AQVL 840 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 V V A D G+ I Y L D + F I+ SG I T + L + Sbjct: 841 VGAVKAGHIDPGITFPITYTLTSGDPND-FFRINTTSGEIFTRGSGPDHEQQAFVLITIQ 899 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 G PP V V+I + D+ND+ P F + I E++ IG++I A D D G N Sbjct: 900 AASGMPPTYDDVQVNITVIDVNDNVPQFMAQTARTSIPESTGIGSSIYVATAMDLDSGDN 959 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR---AASPPLWN 776 +V Y + + N+F + G E++ ++ Y + + +E+ I+ A P L Sbjct: 960 GLVRYRLT-SNPGNTFRIVEATG----EIILNKEVSY-NDQLSFEVDIQAYDAGEPSLEG 1013 Query: 777 DVRVEILVTDVNDNAPV 793 + + +++ DVNDN PV Sbjct: 1014 SLTLTVIILDVNDNGPV 1030 Score = 273 bits (670), Expect = 4e-71 Identities = 203/644 (31%), Positives = 311/644 (48%), Gaps = 55/644 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I ++D ND+ PVF +Q SV E G +V T+ ATD D N + +T T Sbjct: 2275 RIGIVDVNDNQPVF-VQMDPVSVSEDLGVGLSVTTVTATDSDTNPNIQYSFT------ST 2327 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 NP F ID SG + SLDRE YT+ ++ATD Sbjct: 2328 GNPGG--------------YFAIDQYSGIITLARSLDRETQDGYTLELEATDT------E 2367 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 ++T T+ V + D+NDN P F +++Y V++ E N + + A+D D+G N+ + Y Sbjct: 2368 YTTTMTLEVIVTDENDNAPVFRQESYQVTLPE--LTQPNVAVVAVNASDKDIGLNAELTY 2425 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVR-SYRLVIRAQDGGSPSRSNTTQLLINIR 248 + + ++ F ID ++G + + +++ V + +L + A D G+P+ S + I I Sbjct: 2426 SFV--DSHPSFYIDPITGVIFTNQVIEFNDVETTIQLYVTATDSGAPALSEFVTVRIEIT 2483 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYTGNVDL 307 DVN+ +P F ++ SVSENV +G+ ++ V A D D N+++ Y + +GN Sbjct: 2484 DVNNQSPVFVEDIYSASVSENVSLGHHVITVVAEDMDLSPENSKINYFIE----SGNDQG 2539 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 ID G + +LDRE Y L++ A D G+P +ATA F Sbjct: 2540 KFKIDANDGSITVLERLDREATDTYTLIIGAVDNGEPVNNATAEVVIEVEDINDHSPIFD 2599 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITV 425 QYE +AE+ T ++T+ ATD D + + Y I G F+I + G +TV Sbjct: 2600 HVQYEGRIAENATASTYILTVHATDRDIGYNGEVEYSIISGTYSDLFAIDVVS--GAVTV 2657 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTA---MVQINITDANNYAPVFENAPYTASVFEDA 482 LD ++ R TV A+D G + A +V I ITD N + P F Y V E+ Sbjct: 2658 RGELDREEVERVEFTVQASDRGMENQLASVVLVTITITDFNEFPPYFPQLFYHFLVPENM 2717 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 P+ T V A D+D G ++TYS I ++ D F I+P TG + T + D E Sbjct: 2718 PVETYVFTAGALDNDAGEYGELTYS----IRGLGPSNGDDYFTIDPVTGEVFTAAVFDYE 2773 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 + + Y V A+D G S+S T+V I+ VD + P+F Q Y I + A G V Q Sbjct: 2774 SANSYRFVVQAQDTGGLSISIQTEVNITSVD--EFPPMFNDQEYYFEIGDGADAGDYVGQ 2831 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646 V ATDAD G +G + Y L + F I+ +G+I+ K L+ Sbjct: 2832 VTATDADGGEDGVVIYSLTHE-----FFYIEATTGIIKVAKPLN 2870 Score = 200 bits (488), Expect = 4e-49 Identities = 169/474 (35%), Positives = 223/474 (47%), Gaps = 40/474 (8%) Query: 377 EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ--E 434 E++P GT V +L +D T N F I S G +IT LD + + Sbjct: 92 ENQPVGTFVGSL-----QDDTSFGSPFTTLNPSAEFMIESDTG--IITTGAVLDRETAPD 144 Query: 435 RRYVLTVSATDSGGRSDTAMV-QINITDANNYAPVFENAPYTASVFEDA-PIGTTVLVVS 492 + +V+ V A G TA+V I + D N+ P+F T V E P T + V+ Sbjct: 145 QEFVIIVFA----GEMFTALVVTIRLNDTNDNNPIFSQDNRTFEVTEAVQPYMTKINGVT 200 Query: 493 ATDSDVGINAQITYSL-SSEISNEAVAHHDQQFVINPQTGA---ITTNKLLDRETMSGYL 548 ATD+D GIN Y + I N D + +TG I NK LDRET+S Y Sbjct: 201 ATDADEGINGIQGYRIVGGNIDNT----FDLDVRVR-ETGVYMDIVVNKTLDRETISMYT 255 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 L + A DGG P L+ T V I V DVNDN PVF +TA I E A V T+V QV A+D Sbjct: 256 LIIEAYDGGDPRLTANTTVNIKVTDVNDNSPVFTLTSFTATINESAPVNTTVLQVTASDE 315 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 D GLNG + + L R++G F IDPASG++ NK L+ E HD +A D PP S Sbjct: 316 DEGLNGEVVFNL---QRDDGFFRIDPASGIVYLNKVLNYEDAQAHDFLVIAQDKAEPPMS 372 Query: 669 S-TVIVHIKIEDINDSPP----VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 S V I + +IN+ PP +F D +SE + TT+ I DPD+G V Sbjct: 373 SQPAYVSIMVININEKPPSLEVLFLPDGGASQVSEAAVADTTLARISVTDPDDGVLTNVS 432 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRV 780 +I GG + Q T D E Y++ IRA SPP + + Sbjct: 433 MTITGGAGQFDLQKNSNQVYFLIVATTASSFDREEV-ASYDISIRATDHGSPPQHAEENL 491 Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRI 831 I VTDVNDN P+ D + + G P +V A DAD V ++ YRI Sbjct: 492 TIAVTDVNDNPPIF-DLPLYHATIIEASEPGTPVKQVHATDADEGVNAQIIYRI 544 Score = 167 bits (407), Expect = 3e-39 Identities = 137/453 (30%), Positives = 205/453 (45%), Gaps = 37/453 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIG-KNAEVEYTIELVTAD 68 +I + D N+ SPVF Y ASV E S G V+T+ A D D+ +N+++ Y IE Sbjct: 2479 RIEITDVNNQSPVFVEDIYSASVSENVSLGHHVITVVAEDMDLSPENSKINYFIE----- 2533 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 + D Q F+ID G++ LDRE YT+++ A D PV+ Sbjct: 2534 --SGND------------QGKFKIDANDGSITVLERLDREATDTYTLIIGAVDNGEPVN- 2578 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 ++TA + + + D ND+ P F Y + E + T + I + ATD D+G N + Sbjct: 2579 --NATAEVVIEVEDINDHSPIFDHVQYEGRIAE--NATASTYILTVHATDRDIGYNGEVE 2634 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR-SNTTQLLINI 247 Y+II G F+ID +SG V++ LD E+V ++A D G ++ ++ + I I Sbjct: 2635 YSIISGTYSDLFAIDVVSGAVTVRGELDREEVERVEFTVQASDRGMENQLASVVLVTITI 2694 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 D N+ P F + V EN+P+ + A D D G ELTY++ N D Sbjct: 2695 TDFNEFPPYFPQLFYHFLVPENMPVETYVFTAGALDNDAGEYGELTYSIRGLG-PSNGDD 2753 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 TIDP +G V+T+ D E+ Y+ +V A D G S + F Sbjct: 2754 YFTIDPVTGEVFTAAVFDYESANSYRFVVQAQDTGG--LSISIQTEVNITSVDEFPPMFN 2811 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITV 425 +Y E+ + G V +TATDAD ED + Y + T F I + G+I V Sbjct: 2812 DQEYYFEIGDGADAGDYVGQVTATDADGGEDGVVIYSL----THEFFYIEATT--GIIKV 2865 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN 458 A+PL+ +R L T R Q N Sbjct: 2866 AKPLNSSARKRRGLEDRFTHRSRREIDLSAQSN 2898 Score = 40.7 bits (91), Expect = 0.57 Identities = 53/228 (23%), Positives = 94/228 (41%), Gaps = 24/228 (10%) Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747 + D L + + EN P+GT +G ++ P + + S F +E SD Sbjct: 82 QQDLLYYSVKENQPVGTFVGSLQDDTSFGSPFTTL-------NPSAEFMIE----SDTGI 130 Query: 748 LVTMVDLDYE-SPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKD 806 + T LD E +P +++ +++ A ++ + V I + D NDN P+ F + Sbjct: 131 ITTGAVLDRETAPDQEFVIIVFAGE--MFTALVVTIRLNDTNDNNPIFSQDNRTFEVTEA 188 Query: 807 CFP-VGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLN---ETTG---SMTLSPQLNT 857 P + V A DAD + YRI+ GN N L+ TG + ++ L+ Sbjct: 189 VQPYMTKINGVTATDADEGINGIQGYRIVGGNIDNTFDLDVRVRETGVYMDIVVNKTLDR 248 Query: 858 NVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTA 905 + T+ + DG + + +V + ++ NS L TA Sbjct: 249 ETISMYTLIIEAYDG-GDPRLTANTTVNIKVTDVNDNSPVFTLTSFTA 295 Score = 38.7 bits (86), Expect = 2.3 Identities = 17/56 (30%), Positives = 32/56 (57%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 I ++N+ ++ P+F Q+Y + +GA +G V + ATD D G++ V Y++ Sbjct: 2794 IQTEVNITSVDEFPPMFNDQEYYFEIGDGADAGDYVGQVTATDADGGEDGVVIYSL 2849 >UniRef50_Q6V0I7 Cluster: FAT tumor suppressor homolog 4; n=35; Euteleostomi|Rep: FAT tumor suppressor homolog 4 - Homo sapiens (Human) Length = 3222 Score = 397 bits (977), Expect = e-108 Identities = 282/857 (32%), Positives = 427/857 (49%), Gaps = 73/857 (8%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 I N+LD ND+ P+F + Y S+ E G+TVL TD D G N+++ Y+I + Sbjct: 226 IRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSI--AS 283 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 D+L F +D ++G L +LDRE + Y ++V+ D Sbjct: 284 GDSLGQ-----------------FTVD-KNGVLKVLKALDRESQSFYNLVVQVHDLPQIP 325 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 + R +STA + + ++D NDN P F T + E+ + + V+ K +ATD D G NS Sbjct: 326 ASRFTSTAQVSIILLDVNDNPPTFLSPKLTY-IPENTPI--DTVVFKAQATDPDSGPNSY 382 Query: 187 IRYAIIG--GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 I Y ++ GN +FSI ++ G+V L LD E+V +Y L + A D G PS S++T+++ Sbjct: 383 IEYTLLNPLGN---KFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVV 439 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + + D+NDN P F +L++ ++EN G I++V A D DEG N ++ Y + + GN Sbjct: 440 VMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVN----GN 495 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 + ID +G + + LDRE Y L V ATD G PR+ T+T Sbjct: 496 TNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVP 555 Query: 365 XFMPGQYEVELAED--EPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGR 420 F Y V + E+ P T ++ + A D D +++L Y + GGN F++++ Sbjct: 556 VFELSPYSVNVPENLGTLPRT-ILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLSAS--- 611 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASV 478 G + V Q LD + + R+VL ++ATDSG + T IN+ D N+ P F + Y ++ Sbjct: 612 GELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTFASKAYFTTI 671 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 EDAP GT VL+V+A+D+D NA I + + QF INP TG I T+ L Sbjct: 672 PEDAPTGTDVLLVNASDADASKNAVIR-----------IIGGNSQFTINPSTGQIITSAL 720 Query: 539 LDRETMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LDRET Y L V D G P LS +T V ++V DVNDN P F+ Y +I L G Sbjct: 721 LDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPG 780 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 + V V TDAD+G N +HY L ++ E+ F IDP G I L+ S T + Sbjct: 781 SFVFAVTVTDADIGPNSELHYSLSGRNSEK--FHIDPLRGAIMAAGPLNGASEVTFSVHV 838 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 DGG+ P++ + V ++ + D P V + TF EN P+ + + I Sbjct: 839 K--DGGSFPKTDSTTVTVRFVNKADFPKVRAKE-QTFMFPENQPVSSLVTTITGSSLRGE 895 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPL 774 P + Y I G+ N+F ++ G ++ LD+E +KY + I A PP Sbjct: 896 P---MSYYIASGNLGNTFQIDQLTG----QVSISQPLDFEK-IQKYVVWIEARDGGFPPF 947 Query: 775 WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRIL 832 + +++I V DVNDNAP+ K+ I ++ P V A D D +L Y I+ Sbjct: 948 SSYEKLDITVLDVNDNAPIFKEDPFISEILENLSP-RKILTVSAMDKDSGPNGQLDYEIV 1006 Query: 833 SGNNANLILLNETTGSM 849 +GN N +N TG + Sbjct: 1007 NGNMENSFSINHATGEI 1023 Score = 386 bits (951), Expect = e-105 Identities = 421/1648 (25%), Positives = 689/1648 (41%), Gaps = 184/1648 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND++P F Y E G+ V + ATD D G N +V Y I+ Sbjct: 1158 IFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIK------- 1210 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA--------RYTVLVKATDQ 122 + FRI+ +G + + L + V R++ +V ++D+ Sbjct: 1211 --------------SQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDR 1256 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 P L S T+ +NI+D NDN PQF + Y V +++ V +I D D G Sbjct: 1257 GKP---SLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKV-GTKLIRVTAIDDKDFG 1312 Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 NS + Y I N +F +D+ +G +S+ +L + +++ + + A+D G+P S+ Sbjct: 1313 LNSEVEYFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQAT 1372 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 + I + + N + P F S ++ E+ IG + V A D D +N + Y+++ + Sbjct: 1373 VHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSIS----S 1428 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 GN + I+ +G + + LD E K+++ ++A DGG R+ + Sbjct: 1429 GNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDN 1488 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422 F+ Y + E+ P GT V+ L ATDAD T ++ + N G+ Sbjct: 1489 SPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPN-TGV 1547 Query: 423 ITVAQPLDFKQERRYVLTVSATD--SGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 IT LDF+ ++ Y LTV A + R A V I + N Y P F + Y + E Sbjct: 1548 ITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISE 1607 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 AP GT V V A+D D+G + ++ Y + + F IN +TG I + +LD Sbjct: 1608 AAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKG-------FQINKKTGQIYVSGILD 1660 Query: 541 RETMSGYLLTVTARD-GGVPSLS-DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 RE L V A++ G + D V ++V+D ND P+F +Y+ I E +GT Sbjct: 1661 REKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGT 1719 Query: 599 SVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 V+ V A D+D + R Y + E G+F I+P +G I LDRE++ ++L Sbjct: 1720 HVTFVSAFDSDSIPSWSRFSYFIG-SGNENGAFSINPQTGQITVTAELDRETLPIYNLSV 1778 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 +A+D GTP + + + + +EDIND+ P+ + EN GT + +++ DPD Sbjct: 1779 LAVDSGTPSATGSASLLVTLEDINDNGPMLTVS--EGEVMENKRPGTLVMTLQSTDPDLP 1836 Query: 718 PNA--VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--PP 773 PN +Y + G ++ FSL T L T ++D E Y V+ S P Sbjct: 1837 PNQGPFTYYLLSTGPATSYFSLSTA-----GVLSTTREIDREQIADFYLSVVTKDSGVPQ 1891 Query: 774 LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILS 833 + + V I V D NDN + +I N Y + FP G G V D DV D + S Sbjct: 1892 MSSTGTVHITVIDQNDNPSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDVLDSFHCSLTS 1951 Query: 834 GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE-IKAMMQLSVRLITEEML 892 G +L + T + P+ L + DGV+ + + +++ + + Sbjct: 1952 G-VTSLFSIPGGTCDLNSQPRSTDGTFDLTVLS---NDGVHSTVTSNIRVFFAGFSNATV 2007 Query: 893 LNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFS 952 NSI +RL T + FL+ F+ ++ + + ++S ++ + T + Sbjct: 2008 DNSILLRLGVPTVKDFLTNHYLHFLRIASSQLTGLGTAVQLYSAYEENNRTFLL------ 2061 Query: 953 ARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEE 1012 V + + + +P+ + + L R + V+V D + CVH PC N Sbjct: 2062 -------AAVKRNHNQYVNPSGVATFFESIKEILLRQSGVKVESVDHDSCVHGPCQNGGS 2114 Query: 1013 CLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKA---------- 1062 CL L + S V+ P+ F C+C G+ G CE + + Sbjct: 2115 CLRRLAVSSVLKSRESLPVIIVANEPLQPFLCKCLPGYAGSWCEIDIDECLPSPCHSGGT 2174 Query: 1063 --------SCEV-DG-DGSIC-RSGSQCV-ARREGGILCQ------GCSIDAAYTTAV-- 1102 SC DG G C R ++C+ + + G +CQ C YT Sbjct: 2175 CHNLVGGFSCSCPDGFTGRACERDINECLQSPCKNGAICQNFPGSFNCVCKTGYTGVFGK 2234 Query: 1103 -CELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYN--GRYNERHDFLALEL 1159 CEL + F S++ FP L + ++ +KFAT + LLLYN + +R +FLALE+ Sbjct: 2235 HCELNSYGFEELSYMEFPSLDPNNN-YIYVKFATIKSHALLLYNYDNQTGDRAEFLALEI 2293 Query: 1160 VSSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKVL 1219 LRFS++LG G ++T V DG +HTV ++ +D C + Sbjct: 2294 AEER--------LRFSYNLGSGTYKLTTMKKVSDGHFHTVIARRAGMAASLTVDSCSENQ 2345 Query: 1220 SLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNK 1279 G ++T V P R T L LQ G V++ Sbjct: 2346 E-PGYCTVSNVAVSDDWTLDVQPNRV-----TVGGIRSLEPILQRRG--------HVESH 2391 Query: 1280 DFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDC 1339 DFVGCI +F ++ + ++ + +A G L + S C+ +C + T D Sbjct: 2392 DFVGCIMEFAVNGRPLEPSQALAAQGILDQYGDFISY-----CFKEKKCKKVCFTVTPDT 2446 Query: 1340 KEGHTGKDCAD---STGPPWRFGGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMSIQ 1396 GK D S + L +L P + L + RTR + ++ IQ Sbjct: 2447 ALSLEGKGRLDYHMSQNEKREYLLRQSLR-GAMLEPFGVNSLE-VKFRTRSENGVLIHIQ 2504 Query: 1397 ---------LKSGLLHYSYN----GET-MYLPMATLSDGAWHRIEIKWLGTDISVTVD-- 1440 +K+G ++++ + G+ +P ++DG WH I GT ++VD Sbjct: 2505 ESSNYTTVKIKNGKVYFTSDAGIAGKVERNIPEVYVADGHWHTFLIGKNGTATVLSVDRI 2564 Query: 1441 YGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGLLASDVGFFEGCIQDVRIG-------T 1493 Y R ++ P G + I +GG+ + F+GCI + G Sbjct: 2565 YN-RDIIHP--TQDFGGLDVLTISLGGIPPNQAHRDAQTAGFDGCIASMWYGGESLPFSG 2621 Query: 1494 AQSLLNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACE 1553 SL + +V+ GC+ C + C C+ W + C V P C Sbjct: 2622 KHSLASISKTDPSVKIGCRGPNICASNPCWGDLLCINQWYAYRC------VPP---GDCA 2672 Query: 1554 LGPC-GAARCVPDQTPKGYSCACEPGYT 1580 PC C P G++C+C +T Sbjct: 2673 SHPCQNGGSCEPG-LHSGFTCSCPDSHT 2699 Score = 371 bits (912), Expect = e-100 Identities = 283/876 (32%), Positives = 429/876 (48%), Gaps = 72/876 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I + D ND+ PVF + +V E G+ ++ L A D D G NA V YTI + AD Sbjct: 25 EITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTI-ISGAD- 82 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 D FRID SG L+ LDRE+ ++Y++LV+A D Sbjct: 83 ------------------DSFRIDPESGDLIATRRLDRERRSKYSLLVRADDGLQ----- 119 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 SS I++ + D ND+ P+FS Y+ + ED ++A I ATD D G N I Y Sbjct: 120 -SSDMRINITVSDVNDHTPKFSRPVYSFDIPED--TIPGSLVAAILATDDDSGVNGEITY 176 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 + + F ++ ++G +L + LDYE + Y L +RA+DGG + T ++ NI D Sbjct: 177 IVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGG--GQFTTIRVYFNILD 234 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 VNDN P F + + S+ EN+P+G +++ DAD+G+N++LTY++ D G Sbjct: 235 VNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQ----F 290 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRS---ATATXXXXXXXXXXXXXXF 366 T+D ++G + LDRE+Q+ Y L+V D P S +TA F Sbjct: 291 TVD-KNGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTF 349 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG-RFSITSQNGRGLITV 425 + + + E+ P T V ATD D + E T N G +FSI + +G + + Sbjct: 350 LSPKL-TYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGE--VRL 406 Query: 426 AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 LD ++ Y LTV ATD G S + V + + D N+ P+F A Y + E+ Sbjct: 407 TGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTL 466 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 GT ++ V A D D G N Q+ Y + + +N Q+F I+ TGAIT K LDRE Sbjct: 467 TGTDIIQVFAADGDEGTNGQVRYGIVNGNTN-------QEFRIDSVTGAITVAKPLDREK 519 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED-ALVGTSVSQ 602 Y LTV A D G +DT+ V I ++D+ND PVF+ Y+ N+ E+ + ++ Q Sbjct: 520 TPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQ 579 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 V A D D G N ++ Y L E+ +F + ASG + ++LDRE+ L A D Sbjct: 580 VVARDDDRGSNSKLSYVLF-GGNEDNAFTLS-ASGELGVTQSLDRETKERFVLMITATDS 637 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 G+P + T +++ ++D+ND+ P F S I E++P GT + + A D D NAV+ Sbjct: 638 GSPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVI 697 Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI---RAASP-PLWNDV 778 I GG ++ F++ G +++T LD E+ + Y LV+ A SP PL + Sbjct: 698 R--IIGG--NSQFTINPSTG----QIITSALLDRET-KDNYTLVVVCSDAGSPEPLSSST 748 Query: 779 RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNN 836 V + VTDVNDN P + + + P V DAD+ +L Y LSG N Sbjct: 749 SVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYS-LSGRN 807 Query: 837 ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 + ++ G++ + LN T V V DG Sbjct: 808 SEKFHIDPLRGAIMAAGPLNG--ASEVTFSVHVKDG 841 Score = 350 bits (861), Expect = 3e-94 Identities = 252/770 (32%), Positives = 374/770 (48%), Gaps = 48/770 (6%) Query: 114 TVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK 173 TV+ A P++ + + + + D NDN P F ++V+E+I D I + Sbjct: 4 TVVAVGDTLAQPLA--AAEVFIVEITLQDINDNPPVFPTDMLDLTVEENIG--DGSKIMQ 59 Query: 174 IKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233 + A DAD GAN+ + Y II G F ID SGD+ + LD E+ Y L++RA DG Sbjct: 60 LTAMDADEGANALVTYTIISGADD-SFRIDPESGDLIATRRLDRERRSKYSLLVRADDG- 117 Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293 +S+ ++ I + DVND+ P+F ++ + E+ G + + A D D GVN E+T Sbjct: 118 --LQSSDMRINITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEIT 175 Query: 294 YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353 Y + + D G L +P +G + LD E Q Y L V A DGG + T Sbjct: 176 YIVNEDDEDGIFFL----NPITGVFNLTRLLDYEVQQYYILTVRAEDGGG--QFTTIRVY 229 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGR 411 F Y L E+ P G+ V+ TDAD+ +++L Y I G++ G+ Sbjct: 230 FNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQ 289 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATD-----SGGRSDTAMVQINITDANNYA 466 F++ G++ V + LD + + Y L V D + + TA V I + D N+ Sbjct: 290 FTVDKN---GVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNP 346 Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 P F + P + E+ PI T V ATD D G N+ I Y+L + + N+ F I Sbjct: 347 PTFLS-PKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNK--------FSI 397 Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586 G + LDRE +S Y LTV A D G PSLS +T+V + V+D+NDN P+F Q LY Sbjct: 398 GTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALY 457 Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646 I E+ L GT + QV A D D G NG++ Y + + + F ID +G I K LD Sbjct: 458 KVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQ-EFRIDSVTGAITVAKPLD 516 Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN-SPIGTT 705 RE T+ L A D G+ P++ T V I + DIND PVFE + + EN + T Sbjct: 517 REKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRT 576 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765 I ++ A D D G N+ + Y + GG++ N+F+L S EL LD E+ ++++ L Sbjct: 577 ILQVVARDDDRGSNSKLSYVLFGGNEDNAFTL-----SASGELGVTQSLDRET-KERFVL 630 Query: 766 VIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDA 821 +I A SP L + ++V DVNDN P + F + P G V A DA Sbjct: 631 MITATDSGSPALTGTGTINVIVDDVNDNVPTFAS-KAYFTTIPEDAPTGTDVLLVNASDA 689 Query: 822 DVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 D + RI+ GN+ +N +TG + S L+ T+ V +D Sbjct: 690 DASKNAVIRIIGGNSQ--FTINPSTGQIITSALLDRETKDNYTLVVVCSD 737 Score = 347 bits (853), Expect = 3e-93 Identities = 248/829 (29%), Positives = 406/829 (48%), Gaps = 48/829 (5%) Query: 54 KNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARY 113 +N V + +T +L E + + F+ID +G + LD EK+ +Y Sbjct: 876 ENQPVSSLVTTITGSSLRGEPMSYYIASGN--LGNTFQIDQLTGQVSISQPLDFEKIQKY 933 Query: 114 TVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK 173 V ++A D P SS + + ++D NDN P F E + + E++S I Sbjct: 934 VVWIEARDGGFPP---FSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPRK---ILT 987 Query: 174 IKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233 + A D D G N + Y I+ GN + FSI+ +G++ V+ LD E+V Y L I++ D G Sbjct: 988 VSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKG 1047 Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293 SPS+S + +++INI D NDNAPRF + +F V EN P+GY++ RV D D G+NA Sbjct: 1048 SPSQSTSVKVMINILDENDNAPRF-SQIFSAHVPENSPLGYTVTRVTTSDEDIGINAISR 1106 Query: 294 YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353 Y++ D LP TI+P +G + S L+RE +Y++ V+A D G + + Sbjct: 1107 YSIMD------ASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSG---WTVSTDVT 1157 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGR 411 F Y ++ E G+ V + ATD DE + ++ Y I + R Sbjct: 1158 IFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEYFR 1217 Query: 412 FSITSQN--GRGLITVAQPLDFKQE--RRYVLTVSATDSGGRS--DTAMVQINITDANNY 465 + T+ + ++ F R+ V+++D G S V INI D+N+ Sbjct: 1218 INATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDN 1277 Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSA-TDSDVGINAQITYSLSSEISNEAVAHHDQQF 524 AP F + Y V ++ +GT ++ V+A D D G+N+++ Y +S++ +H +F Sbjct: 1278 APQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISND-------NHLGKF 1330 Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584 ++ TG I+ L + + +TVTA+D G P LS V I+V + N + P F Q Sbjct: 1331 KLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQS 1390 Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA 644 +A I E +G+ V V A D D +NG I Y + EEG F I+ ++G++ KA Sbjct: 1391 HMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSIS-SGNEEGIFAINSSTGILTLAKA 1449 Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 LD E H++ AIDGG ++ V + + D+ND+ PVF SD + EN+P GT Sbjct: 1450 LDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVLENAPSGT 1509 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764 T+ + A D D G NAV+ Y+++ DS+ F ++ G + T LD+E+ ++ Y Sbjct: 1510 TVIHLNATDADSGTNAVIAYTVQ-SSDSDLFVIDPNTG----VITTQGFLDFET-KQSYH 1563 Query: 765 LVIRAASPP---LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYD 820 L ++A + P + V I + N+ P ++ + + P G G V A D Sbjct: 1564 LTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVS-KLYYFEISEAAPKGTIVGEVFASD 1622 Query: 821 ADV-TD-KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867 D+ TD ++ Y I + +N+ TG + +S L+ + +++V Sbjct: 1623 RDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKV 1671 Score = 345 bits (847), Expect = 1e-92 Identities = 256/887 (28%), Positives = 438/887 (49%), Gaps = 69/887 (7%) Query: 4 PFCIHQQ--INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 PF +++ I VLD ND++P+F+ + + + E S +LT+ A D+D G N +++Y Sbjct: 946 PFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSP-RKILTVSAMDKDSGPNGQLDY- 1003 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121 E+V + +++ F I+ +G + + LDREKV+ Y + +K++D Sbjct: 1004 -EIVNGN-----------------MENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSD 1045 Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181 + SP S++ + +NI+D+NDN P+FS+ ++ V E+ + + ++ +D D+ Sbjct: 1046 KGSPSQ---STSVKVMINILDENDNAPRFSQ-IFSAHVPENSPL--GYTVTRVTTSDEDI 1099 Query: 182 GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 G N+ RY+I+ + + F+I+ +GD+ + + L+ E YR+ + A D G + +T Sbjct: 1100 GINAISRYSIM--DASLPFTINPSTGDIVISRPLNREDTDRYRIRVSAHDSG---WTVST 1154 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM-TDKD 300 + I + D+NDNAPRF + + E IG + +V A D DEG N ++ Y + + + Sbjct: 1155 DVTIFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSE 1214 Query: 301 Y------TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354 Y TG + + ++ +++ ++R + +VT++D G P + T Sbjct: 1215 YFRINATTGEIFNKQILKYQNVTGFSNVNINR-----HSFIVTSSDRGKPSLISETTVTI 1269 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE---DNRLHYEITGGNTRGR 411 F+ +Y + ++ GT ++ +TA D + ++ + Y I+ N G+ Sbjct: 1270 NIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGK 1329 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVF 469 F + N G I+VA L + + +TV+A D G S A V I +T+ N + P F Sbjct: 1330 FKL--DNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEF 1387 Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 + +A++ E IG+ V VSA D D +N I YS+SS NE + F IN Sbjct: 1388 SQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISS--GNE-----EGIFAINSS 1440 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589 TG +T K LD E + +T++A DGG + + V ++V+DVNDN PVF Y Sbjct: 1441 TGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPT 1500 Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES 649 ++E+A GT+V + ATDAD G N I Y + D + FVIDP +GVI T LD E+ Sbjct: 1501 VLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSD--LFVIDPNTGVITTQGFLDFET 1558 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 ++ L A + + S V+I+++ N+ P F S F ISE +P GT +GE+ Sbjct: 1559 KQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEV 1618 Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 A D D G + VHY I G F + + G + + ++D + E R +++ + Sbjct: 1619 FASDRDLGTDGEVHYLIFGNSRKKGFQINKKTG--QIYVSGILDREKEE-RVSLKVLAKN 1675 Query: 770 ASPPLWNDV-RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR-VPAYDADVT--- 824 D+ V + VT ++ N P + I + P+G V A+D+D Sbjct: 1676 FGSIRGADIDEVTVNVTVLDANDPPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSW 1735 Query: 825 DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + Y I SGN +N TG +T++ +L+ + + V D Sbjct: 1736 SRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVD 1782 Score = 338 bits (832), Expect = 9e-91 Identities = 252/802 (31%), Positives = 396/802 (49%), Gaps = 70/802 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 IN+LD ND++P F Q + A V E + G TV + +D+DIG NA Y+I D Sbjct: 1059 INILDENDNAPRFS-QIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSI----MDAS 1113 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P F I+ +G ++ L+RE RY + V A D V Sbjct: 1114 LP-----------------FTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTV---- 1152 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+ TI V D NDN P+FS +Y + E + + ++ ATD D G+N + Y Sbjct: 1153 STDVTIFVT--DINDNAPRFSRTSYYLDCPELTEIGSK--VTQVFATDPDEGSNGQVFYF 1208 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY--------RLVIRAQDGGSPSRSNTTQ 242 I + F I++ +G++ + L Y+ V + ++ + D G PS + T Sbjct: 1209 I--KSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETT 1266 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY-DADEGVNAELTYTMTDKDY 301 + INI D NDNAP+F S + V++NV +G ++RV A D D G+N+E+ Y +++ ++ Sbjct: 1267 VTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNH 1326 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 G L D +GW+ + L + + + VTA D G+PP S+ AT Sbjct: 1327 LGKFKL----DNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENY 1382 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNG 419 F + E G+ V T++A D D + + Y I+ GN G F+I S Sbjct: 1383 HTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAINSST- 1441 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477 G++T+A+ LD++ +++ +T+SA D G R+ V +N+ D N+ +PVF + Y + Sbjct: 1442 -GILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPT 1500 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 V E+AP GTTV+ ++ATD+D G NA I Y++ S S+ FVI+P TG ITT Sbjct: 1501 VLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSD--------LFVIDPNTGVITTQG 1552 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LD ET Y LTV A + V I + N+ P F +LY I E A G Sbjct: 1553 FLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKG 1612 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 T V +V A+D D+G +G +HY + R++G F I+ +G I + LDRE LK Sbjct: 1613 TIVGEVFASDRDLGTDGEVHYLIFGNSRKKG-FQINKKTGQIYVSGILDREKEERVSLKV 1671 Query: 658 VAIDGGT--PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 +A + G+ V V++ + D ND PP+F + + ISE PIGT + + A D D Sbjct: 1672 LAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSD 1730 Query: 716 EGPN-AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES-PRKKYE-LVIRAASP 772 P+ + Y I G+++ +FS+ + G ++ +LD E+ P L + + +P Sbjct: 1731 SIPSWSRFSYFIGSGNENGAFSINPQTG----QITVTAELDRETLPIYNLSVLAVDSGTP 1786 Query: 773 PLWNDVRVEILVTDVNDNAPVM 794 + + + D+NDN P++ Sbjct: 1787 SATGSASLLVTLEDINDNGPML 1808 Score = 38.7 bits (86), Expect = 2.3 Identities = 14/33 (42%), Positives = 18/33 (54%), Gaps = 1/33 (3%) Query: 1317 CSSAPCYNGAECSD-LWDTYICDCKEGHTGKDC 1348 C+S PC NG C L + C C + HTG+ C Sbjct: 2671 CASHPCQNGGSCEPGLHSGFTCSCPDSHTGRTC 2703 >UniRef50_UPI0000E48843 Cluster: PREDICTED: similar to Fat4; n=2; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Fat4 - Strongylocentrotus purpuratus Length = 4811 Score = 396 bits (975), Expect = e-108 Identities = 328/1097 (29%), Positives = 512/1097 (46%), Gaps = 84/1097 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVRE-GASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +NV D ND++PVF + E SSG + T+ ATD D G N +V+Y ++ +T Sbjct: 2699 VNVEDTNDNAPVFTENSINTTYPEIFFSSGNVIATVSATDADDGDNGQVDYILKTMT--- 2755 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 E + V I + + + D YT V A D+ +P Sbjct: 2756 ---EHFRVETINNRGWIFPVPPI-----SYIVPSPEDTSNPNTYTFSVFAVDRGTPA--- 2804 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L A++ + + DN P F+ +Y V + N + ++ A D D G+N+AI Y Sbjct: 2805 LYGEASVIITVTQDNSYTPVFATPSYFSPVTAN--TRSNTRVLQVLAVDQDTGSNAAITY 2862 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVK--TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 +I GN +F +++ +G + L K +L + +Y+L+++A D G+ + + T + I Sbjct: 2863 SISDGNGTEKFDVEADTGWI-LTKGVSLAGDVGITYQLLVKATDNGNIKKEDETTVTFLI 2921 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 D NDNAP F ++ S++E+V GY + V+A D D G+N E+TY+++ D Sbjct: 2922 TDSNDNAPVFDDDTYRSSIAEDVG-GY-VATVRAEDDDSGINGEITYSISGADAA----- 2974 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 +ID SG V G LDRET ++Q+ VTA D +SATA F+ Sbjct: 2975 LFSIDAVSGIVSLVGSLDRETSDEHQIQVTAEDRAMYSQSATAILIVTVTDVDDNPPVFL 3034 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYE--ITGGNTRGRFSITSQNGRGLITV 425 P +Y ++ E+ P TPVVT+TATDAD +E I+GG+ F+I + G LI Sbjct: 3035 PREYRADVFENSPSATPVVTVTATDADTGTNADFEYIISGGDGTDFFTINPETG--LILT 3092 Query: 426 AQPLDFKQERR-YVLTVSATDSGGRS-DTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 LD++ + Y LTV+AT+ D A V + + N + P F Y V E A Sbjct: 3093 QGNLDYETGKTTYHLTVAATNEQATMVDYAHVIVTLLGENEFYPQFTQHQYDFYVNEHAT 3152 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT---NKLLD 540 G V VV ATD D+G + + Y SN Q F +N ++G IT N LD Sbjct: 3153 DGAPVGVVLATDDDLGDDGIVNYLFIGG-SNL------QGFNVNLESGQITVAYENGRLD 3205 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE--PVFKQQLYTANIMEDALVGT 598 RET LL+V A++ G + +D + E+ ++ VND PVF + Y A ++E G+ Sbjct: 3206 RETADTVLLSVLAKNEGPITGADIDEAEV-IIHVNDGNDAPVFSSEQYQARVLESEPPGS 3264 Query: 599 SVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 V+ V A D D + + +Y + + E +F ID +G I T LDRE+++ + L Sbjct: 3265 DVTVVTAADYDEIPSFRQFNYSI-LRGNEGDAFHIDARTGRITTASLLDRETLSVYFLTV 3323 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 AID G PPQ+ T +V ++++D+ND+ PVF + + EN P I +RA DPD Sbjct: 3324 AAIDTGNPPQTGTAVVSVELDDVNDNGPVFIGEAAEGSVFENEPPNELIMTLRATDPDSN 3383 Query: 718 PN-AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPP 773 PN + Y++ DS++F L G EL T LD E + Y + I A+ SP Sbjct: 3384 PNPSQFTYTLLTSPDSSAFRL---VGD---ELRTTQTLDRE-VKSDYYIQIEASDGESPA 3436 Query: 774 LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILS 833 + + I + D NDN ++ +I ++ FP G G V D D D +I S Sbjct: 3437 MSATSTIHITIADRNDNPSTLRQARIEVKMFQSMFPGGVIGSVKPIDPDTDDTFFCQITS 3496 Query: 834 GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE-IKAMMQLSVRLITEEML 892 G+ + + + S +T + + VS DG ++ + + + T + L Sbjct: 3497 GDLSKFSIQSNCD---LFSASHSTE--SVVDLSVSGNDGSHQSVTSSFSVVYESFTNDTL 3551 Query: 893 LNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFS 952 NS+T+RL D +AE FL+ F L+A + +E + + S+ D D+ Sbjct: 3552 TNSLTIRLVDTSAEAFLANSYDRFKTSLSAFLG-SRETLIVLSITDHPDLD--------- 3601 Query: 953 ARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEE 1012 + D + + S H L + + + TL + + + D C PCLN Sbjct: 3602 --KVDLVLAIKKQGSQHLLHDDLVDLLEANEATLESQSDITIETIDYTACSDSPCLNSGT 3659 Query: 1013 CLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSI 1072 C SD V+F + SFTC CP F+G CE + C G + Sbjct: 3660 CSHETNINLEELITESDPVIFVGLQTSHSFTCACPAEFSGQRCE--IPTDYC---GQAT- 3713 Query: 1073 CRSGSQCVARREGGILC 1089 C++G+ C GG +C Sbjct: 3714 CKNGATC-QNAIGGYIC 3729 Score = 380 bits (936), Expect = e-103 Identities = 293/889 (32%), Positives = 436/889 (49%), Gaps = 79/889 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NVLD ND++PVF Y AS+RE +S + V T+ ATD D+ + + Y+I V T Sbjct: 1570 VNVLDENDNAPVFTNGPYTASIRENVASNSPVKTVMATDADL--DTIIFYSI--VDGAT- 1624 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 D+F ID +G + TR +DRE A Y + ++A+D L Sbjct: 1625 -----------------DLFSIDSTTGQIRTRGVVDRESSAVYQLQLQASDGT------L 1661 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +ST TI +N++D+NDN P FS TY+ V ED V ++ + + ATD D G N + Y+ Sbjct: 1662 TSTTTIDINLLDENDNDPVFSLSTYSFLVPEDEMVGED--VGVVVATDPDAGLNGEVAYS 1719 Query: 191 II--GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 ++ G + F +D +G L ++LDYE + Y + + A D GS RS+T + IN+ Sbjct: 1720 VVEEGAPGEDVFYLDPATGAFRLQQSLDYEVKQHYFMTVMATDKGSSPRSSTATVYINVE 1779 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 DVNDN P + + E V E+V IG S+V + A D D G N EL +++ +G+ Sbjct: 1780 DVNDNNPVYNPVDYSEEVPEDVAIGTSVVTLTATDLDSGSNGELQFSIA----SGDPSQR 1835 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPP--RSATATXXXXXXXXXXXXXX 365 T+ P +G + T LDRE ++ Y L V A+D DP RS+TA Sbjct: 1836 FTVYP-NGTIVTIKNLDREPESFYNLEVVASDMTLDPEDRRSSTAQVSIIVTDINDNAPR 1894 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV 425 F VE+AED ++ L A D D + + E F+++ G + V Sbjct: 1895 F-TNPDSVEIAEDTRTNVIIMVLRAEDDDVERNSYVEYYLLTPGVPFAVSRVEGN--MQV 1951 Query: 426 AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 PLD + E Y L V ATD G +S T + I ITD N+ AP F PY A++ ED P Sbjct: 1952 TGPLDRETESSYALLVQATDKGTPPQSSTMNLTIYITDVNDNAPAFSMTPYEATLDEDTP 2011 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 +G L V+A+D D G+N+ I YS+ S S A F I+P TG ++ N L+ E Sbjct: 2012 VGLEFLKVTASDPDEGLNSIIRYSIFSGDSGRA-------FAIDPVTGVLSVNSGLNYEQ 2064 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 S Y LTV A+D G + + V I+V DVNDN PVF+ Y +IME+ L + QV Sbjct: 2065 RSSYTLTVRAQDQGYSTQVSSVTVTITVADVNDNAPVFEDS-YAPSIMENNLPNADIVQV 2123 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 A DAD G+NG I++ L+ G F I SG+I+ + LD E +L +A D G Sbjct: 2124 RADDADSGVNGMINFRLE--SDYNGLFTIGSTSGLIQVTEVLDYEDQNEFELIVIAEDSG 2181 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 TP + + + + D ND P F SD +SE++ T + ++ A D D A + Sbjct: 2182 TPSHQTRTTMTLTVNDDNDHDPEFVSDFYRATVSEDASADTFVIQVTATDVD--ATAALR 2239 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP---LWNDVRV 780 Y + D + F+++ G ++T LD E + Y L + P VRV Sbjct: 2240 YRL-NSDIGSKFTIDPLGG----RILTTGLLDRE-VQSSYLLTVTVDDGPSRLATTSVRV 2293 Query: 781 EILVTDVNDN----APVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSG 834 E+L DVNDN +P + + + CF + A D D+ D ++Y I SG Sbjct: 2294 EVL--DVNDNPPRFSPTSYTATLPATSQQGCF----VAAIQATDTDLEDNAAIRYSITSG 2347 Query: 835 NNANLILLNETTGSMTLSPQLNTNVP-KLATMEVSVTDGVNEIKAMMQL 882 + + ++ +T +T + N P L +V G N A +++ Sbjct: 2348 DTSKFVVDQDTGVVITAQGFTDENSPYDLQITAENVASGQNSAVASLRV 2396 Score = 378 bits (929), Expect = e-102 Identities = 285/904 (31%), Positives = 426/904 (47%), Gaps = 67/904 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V+D NDH+P+F + Y A + E G+ V ++ ATD D G NA++ Y+I T D Sbjct: 302 IYVVDENDHAPMFLQESYRAGLLESIQVGSFVKSVTATDADEGINADIVYSI---TGDEY 358 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F+ID +G + TR LD E A+ T+ + A+DQ + + Sbjct: 359 G-----------------WFQIDNGTGLVTTREKLDHETAAQVTLTITASDQGL---EPM 398 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 ++T + ++I D ND YP F++ Y+ +V+E+ D + ++ ATD D G N + Y Sbjct: 399 ANTTILTIDIQDVNDEYPVFNQIAYSETVEENSPARD---LIQVLATDLDNGVNGDVTYT 455 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 FS+D SG + + LD E+ SY L I A DGGSPS T + I + D Sbjct: 456 FSSDQYSGMFSLDPESGLLQITVPLDREEQDSYELEILASDGGSPSLQATATVTIAVLDQ 515 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P+FY + + SV EN P G + V A D D GVN + ++++D Sbjct: 516 NDNPPQFYPTEYYASVIENGPAGLFVTVVSATDLDVGVNGAVIFSLSDSS-------KFQ 568 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 ID SG V T LDRE ++ Y L VTA DG + +AT F Sbjct: 569 IDSYSGNVTTRESLDREQESSYTLTVTAQDGSGQAAAQSATIFVTVTDTLDNPLEFELNP 628 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 Y +L E+ P T V T+ AT D + + Y I G+ G F I +G T++ + Sbjct: 629 YRFQLEENRPNRTEVGTVLATSMDLNVEITYVIVNGDPNGLFVIDFYSGVIKTTLSIDRE 688 Query: 431 FKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 + + LTV A D G ++ +V+I I D N+ APVF V E+ +G Sbjct: 689 AHESASFRLTVLAVD-GSQNGQTVVEIEILDINDNAPVFALPEDQVDVVENWAVGNKFYA 747 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550 TD+D N I Y LS + D +F IN +G + NK L Y L Sbjct: 748 AQVTDADSPPNNVILYDLS--------VNFDDRFGINHTSGVLFLNKDLQNYPEKEYNLQ 799 Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA-NIMEDALVGTSVSQVGATDAD 609 + A D G P LS + ++ ++V DVN+N PVF + T + E V + V ATDAD Sbjct: 800 IQATDYGTPPLSSSMNLLVTVRDVNNNAPVFVDSINTTLRLTESIPVNSIVIHALATDAD 859 Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669 G NG I Y + + + SF I P G++ +ALDRE V +DL A DGG P +S Sbjct: 860 QGTNGLISYRITSGNTD--SFGIFP-DGMVYVKRALDREQVDQYDLTIEATDGGVPSMTS 916 Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729 T+++ I + D ND+ P F++ FY+SE IG +G I A D D G N + YS Sbjct: 917 TLMLEIIVLDENDNRPFFDNATYNFYLSEEDDIGAAVGTIHAVDNDVGGNGELTYSFTA- 975 Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYES-----PRKKYELVIR---AASPPLWNDVRVE 781 + F+L + G+ + + V LD ES + + +R + P L + V Sbjct: 976 -NHTLFTLNSVTGA----ITSKVSLDRESLVEAGQPTTFSIRVRVHDSGQPQLQDHADVN 1030 Query: 782 ILVTDVNDNAPVM--KDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNNA 837 I V D+ND+ PV + +Q + + RV A D DV D + Y I+SGN Sbjct: 1031 IHVVDINDSPPVFNRESYQASVSELAQNETL--IIRVSATDDDVGDNSYILYSIVSGNEE 1088 Query: 838 NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEEMLLNSI 896 ++ G + L L+ V + + V D G+ ++ +++ + ++ E S Sbjct: 1089 KRFHIDHVHGQIVLIAPLDREVTEGYVLRVKARDGGIVPQESFVEVEITVLDENDHRPSF 1148 Query: 897 TVRL 900 +V L Sbjct: 1149 SVDL 1152 Score = 338 bits (831), Expect = 1e-90 Identities = 277/906 (30%), Positives = 427/906 (47%), Gaps = 85/906 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND+SP+F Y A+V E +++GT+V+ L ATD D G N ++ Y ++ Sbjct: 80 VTITDVNDNSPIFTQTTYFATVNESSAAGTSVVHLNATDIDQGSNGDIVYRLK------- 132 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSDR 129 + D F +D +G + L VA Y V ATD+ SP Sbjct: 133 -------------NELTDNFALDPDTGWITLLRQLPY--VANGYLFEVTATDKGSPSQ-- 175 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV---IAKIKATDADVGANSA 186 SS+A ++V + D+ND+ P + S+++ + + +KA D D N Sbjct: 176 -SSSAFVNVMVEDENDHSPVIEVLIPEIEASGVASISETMLPGPLFNLKAIDEDREENGR 234 Query: 187 IRYAIIGGNTQMQFSIDSLS---GDVSLV------KTLDYEQVRSYRLVIRAQDGGSPSR 237 + +I GN + FS S+S GDV + +D E + SY L A+D G+P R Sbjct: 235 VSMSIHSGNDRNDFSGTSISLPTGDVFFLLRVSPSANIDREIIASYNLTFAAEDMGTPPR 294 Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297 ++I + D ND+AP F ++ + E++ +G + V A DADEG+NA++ Y++T Sbjct: 295 RTYRSIIIYVVDENDHAPMFLQESYRAGLLESIQVGSFVKSVTATDADEGINADIVYSIT 354 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357 +Y ID +G V T +LD ET A+ L +TA+D G P + T Sbjct: 355 GDEYGW-----FQIDNGTGLVTTREKLDHETAAQVTLTITASDQGLEPMANTTILTIDIQ 409 Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSIT 415 F Y E E+ P ++ + ATD D + + Y + G FS+ Sbjct: 410 DVNDEYPVFNQIAYS-ETVEENSPARDLIQVLATDLDNGVNGDVTYTFSSDQYSGMFSLD 468 Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAP 473 ++ GL+ + PLD +++ Y L + A+D G S TA V I + D N+ P F Sbjct: 469 PES--GLLQITVPLDREEQDSYELEILASDGGSPSLQATATVTIAVLDQNDNPPQFYPTE 526 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 Y ASV E+ P G V VVSATD DVG+N + +SLS +F I+ +G + Sbjct: 527 YYASVIENGPAGLFVTVVSATDLDVGVNGAVIFSLSD----------SSKFQIDSYSGNV 576 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593 TT + LDRE S Y LTVTA+DG + + + + ++V D DN F+ Y + E+ Sbjct: 577 TTRESLDREQESSYTLTVTAQDGSGQAAAQSATIFVTVTDTLDNPLEFELNPYRFQLEEN 636 Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES--VA 651 T V V AT D LN I Y + D G FVID SGVI+T ++DRE+ A Sbjct: 637 RPNRTEVGTVLATSMD--LNVEITYVIVNGD-PNGLFVIDFYSGVIKTTLSIDREAHESA 693 Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711 + L +A+DG Q+ +V I+I DIND+ PVF + EN +G + Sbjct: 694 SFRLTVLAVDGS---QNGQTVVEIEILDINDNAPVFALPEDQVDVVENWAVGNKFYAAQV 750 Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES-PRKKYELVIRA- 769 D D PN V+ Y + S + + R G + V ++ D ++ P K+Y L I+A Sbjct: 751 TDADSPPNNVILYDL-------SVNFDDRFGINHTSGVLFLNKDLQNYPEKEYNLQIQAT 803 Query: 770 --ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDAD--VT 824 +PPL + + + + V DVN+NAPV D + PV A DAD Sbjct: 804 DYGTPPLSSSMNLLVTVRDVNNNAPVFVDSINTTLRLTESIPVNSIVIHALATDADQGTN 863 Query: 825 DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLS 883 + YRI SGN + + + G + + L+ + + TD GV + + + L Sbjct: 864 GLISYRITSGNTDSFGIFPD--GMVYVKRALDREQVDQYDLTIEATDGGVPSMTSTLMLE 921 Query: 884 VRLITE 889 + ++ E Sbjct: 922 IIVLDE 927 Score = 327 bits (804), Expect = 2e-87 Identities = 266/897 (29%), Positives = 419/897 (46%), Gaps = 79/897 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I++ D ND PVF Y +V E + + + L ATD D G N +V YT ++D Sbjct: 406 IDIQDVNDEYPVFNQIAYSETVEENSPARDLIQVL-ATDLDNGVNGDVTYTF---SSDQY 461 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + +F +D SG L LDRE+ Y + + A+D SP L Sbjct: 462 S----------------GMFSLDPESGLLQITVPLDREEQDSYELEILASDGGSP---SL 502 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +TAT+ + ++D NDN PQF Y SV E+ + + ATD DVG N A+ ++ Sbjct: 503 QATATVTIAVLDQNDNPPQFYPTEYYASVIENGPA--GLFVTVVSATDLDVGVNGAVIFS 560 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + + +F IDS SG+V+ ++LD EQ SY L + AQDG + + + + + + D Sbjct: 561 L---SDSSKFQIDSYSGNVTTRESLDREQESSYTLTVTAQDGSGQAAAQSATIFVTVTDT 617 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 DN F + ++ + EN P + V A D +N E+TY + + D G Sbjct: 618 LDNPLEFELNPYRFQLEENRPNRTEVGTVLATSMD--LNVEITYVIVNGDPNG----LFV 671 Query: 311 IDPRSGWVYTSGQLDRET--QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 ID SG + T+ +DRE A ++L V A DG T +P Sbjct: 672 IDFYSGVIKTTLSIDREAHESASFRLTVLAVDGSQ--NGQTVVEIEILDINDNAPVFALP 729 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 + +V++ E+ G TDAD +N + Y+++ N RF I + G++ + Sbjct: 730 -EDQVDVVENWAVGNKFYAAQVTDADSPPNNVILYDLS-VNFDDRFGINHTS--GVLFLN 785 Query: 427 QPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVF-ENAPYTASVFEDAP 483 + L E+ Y L + ATD G S + + + + D NN APVF ++ T + E P Sbjct: 786 KDLQNYPEKEYNLQIQATDYGTPPLSSSMNLLVTVRDVNNNAPVFVDSINTTLRLTESIP 845 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 + + V+ ATD+D G N I+Y ++S + F I P G + + LDRE Sbjct: 846 VNSIVIHALATDADQGTNGLISYRITS--------GNTDSFGIFPD-GMVYVKRALDREQ 896 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 + Y LT+ A DGGVPS++ T +EI V+D NDN P F Y + E+ +G +V + Sbjct: 897 VDQYDLTIEATDGGVPSMTSTLMLEIIVLDENDNRPFFDNATYNFYLSEEDDIGAAVGTI 956 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV------ATHDLKA 657 A D DVG NG + Y F ++ +G I + +LDRES+ T ++ Sbjct: 957 HAVDNDVGGNGELTYSF---TANHTLFTLNSVTGAITSKVSLDRESLVEAGQPTTFSIRV 1013 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 D G P V+I + DINDSPPVF + +SE + T I + A D D G Sbjct: 1014 RVHDSGQPQLQDHADVNIHVVDINDSPPVFNRESYQASVSELAQNETLIIRVSATDDDVG 1073 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPL 774 N+ + YSI G++ F ++ G ++V + LD E + Y L ++A P Sbjct: 1074 DNSYILYSIVSGNEEKRFHIDHVHG----QIVLIAPLDRE-VTEGYVLRVKARDGGIVPQ 1128 Query: 775 WNDVRVEILVTDVNDNAPVMK-DFQIIFNNYKDCFPVG-PFGRVPAYDADVTD--KLQYR 830 + V VEI V D ND+ P D Q +C +G G V A D D+ ++ Y Sbjct: 1129 ESFVEVEITVLDENDHRPSFSVDLQREI-EVTECLQIGDTIGGVQATDMDINSNGQISYT 1187 Query: 831 ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN-EIKAMMQLSVRL 886 I GN + +N +G + L+ L+ ++ ++ DG + ++A++ + + + Sbjct: 1188 ITGGNLDGVFGVNANSGEVYLTGYLDHEATSQYSLNITARDGGSPSLQAVVSMVINI 1244 Score = 326 bits (801), Expect = 5e-87 Identities = 263/809 (32%), Positives = 393/809 (48%), Gaps = 78/809 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+V+D ND PVF + Y+ASV E A + T ++ + ATD D+G N+ + Y+I V+ Sbjct: 1031 IHVVDINDSPPVFNRESYQASVSELAQNETLIIRVSATDDDVGDNSYILYSI--VSG--- 1085 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N E F ID G ++ A LDRE Y + VKA D + Sbjct: 1086 NEEKR--------------FHIDHVHGQIVLIAPLDREVTEGYVLRVKARDGGIVPQE-- 1129 Query: 131 SSTATIHVNIIDDNDNYPQFS-EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S + + ++D+ND+ P FS + + V E + + D I ++ATD D+ +N I Y Sbjct: 1130 -SFVEVEITVLDENDHRPSFSVDLQREIEVTECLQIGDT--IGGVQATDMDINSNGQISY 1186 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I GGN F +++ SG+V L LD+E Y L I A+DGGSPS ++INIRD Sbjct: 1187 TITGGNLDGVFGVNANSGEVYLTGYLDHEATSQYSLNITARDGGSPSLQAVVSMVINIRD 1246 Query: 250 VNDNAPRF-YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 NDN+P F Y + + E P G+ +VRV A D+D GVN E+ ++++ + +G+ Sbjct: 1247 CNDNSPIFAYVGV--PEIDEEKPEGFEVVRVSASDSDSGVNGEVRFSISSQRPSGDF--- 1301 Query: 309 ITIDPRSGWVYTSGQLDRETQA----KYQLLVTATDGGDP---PRSATATXXXXXXXXXX 361 IDP SGW+ T+ ++DRE++ ++ L V TD P R+AT Sbjct: 1302 FAIDPESGWITTNSRIDRESEIMATDQFILTVHGTDLAVPVESRRTATVDVVIFVRDIND 1361 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNG 419 F Q ++ T V T+ A D D + ++ Y + R + + Sbjct: 1362 NAPRF-TSQQAAAISRSTSANTRVTTVHADDPDTGVNGQVTYTLISTGVPFRLDLIT--- 1417 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGG----RSDTAMVQINITDANNYAPVFENAPYT 475 G +T+ QP+ Y L + A D+G +S + I I+D + + YT Sbjct: 1418 -GELTLTQPIP-SSANIYSLDIRADDAGSNPQQQSTPFSLAIIISDGQSSILNYVQNTYT 1475 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ--TGAI 533 SV E+ P GT ++ V A SD G +A + Y +S+ + D+ +I G I Sbjct: 1476 GSVRENQPAGTEIVTVVAQYSD-GRSATVRYYVSAVTAGGV----DKGSLIRASVTNGII 1530 Query: 534 TTNKLLDRETMSG---YLLTVTARDGGVPSLSDTT-DVEISVVDVNDNEPVFKQQLYTAN 589 T+ +LDRE + G + TV A D S T+ V ++V+D NDN PVF YTA+ Sbjct: 1531 RTDAVLDREDLGGGSSLVATVYAVDTSSSSSHVTSVQVTVNVLDENDNAPVFTNGPYTAS 1590 Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES 649 I E+ + V V ATDAD L+ I Y + D F ID +G IRT +DRES Sbjct: 1591 IRENVASNSPVKTVMATDAD--LDTIIFYSI--VDGATDLFSIDSTTGQIRTRGVVDRES 1646 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 A + L+ A DG +ST + I + D ND+ PVF +F + E+ +G +G + Sbjct: 1647 SAVYQLQLQASDG---TLTSTTTIDINLLDENDNDPVFSLSTYSFLVPEDEMVGEDVGVV 1703 Query: 710 RAHDPDEGPNAVVHYSI--KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 A DPD G N V YS+ +G + F L+ G+ + + LDYE ++ Y + + Sbjct: 1704 VATDPDAGLNGEVAYSVVEEGAPGEDVFYLDPATGAFRLQ----QSLDYE-VKQHYFMTV 1758 Query: 768 RA---ASPPLWNDVRVEILVTDVNDNAPV 793 A S P + V I V DVNDN PV Sbjct: 1759 MATDKGSSPRSSTATVYINVEDVNDNNPV 1787 Score = 323 bits (794), Expect = 4e-86 Identities = 253/815 (31%), Positives = 392/815 (48%), Gaps = 82/815 (10%) Query: 7 IHQQINVLDCNDHSPVFEMQ-QYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELV 65 + +I VLD NDH P F + Q E V E G T+ ++ATD DI N ++ YTI Sbjct: 1132 VEVEITVLDENDHRPSFSVDLQREIEVTECLQIGDTIGGVQATDMDINSNGQISYTI--- 1188 Query: 66 TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125 T L+ VF ++ SG + LD E ++Y++ + A D SP Sbjct: 1189 TGGNLD----------------GVFGVNANSGEVYLTGYLDHEATSQYSLNITARDGGSP 1232 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 L + ++ +NI D NDN P F+ Y + D + + ++ A+D+D G N Sbjct: 1233 ---SLQAVVSMVINIRDCNDNSPIFA---YVGVPEIDEEKPEGFEVVRVSASDSDSGVNG 1286 Query: 186 AIRYAIIGGNTQMQ-FSIDSLSGDVSLVKTLDYEQ----VRSYRLVIRAQDGGSP---SR 237 +R++I F+ID SG ++ +D E + L + D P R Sbjct: 1287 EVRFSISSQRPSGDFFAIDPESGWITTNSRIDRESEIMATDQFILTVHGTDLAVPVESRR 1346 Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297 + T ++I +RD+NDNAPRF TS ++S + + V A D D GVN ++TYT+ Sbjct: 1347 TATVDVVIFVRDINDNAPRF-TSQQAAAISRSTSANTRVTTVHADDPDTGVNGQVTYTLI 1405 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXX 355 TG +P +D +G + + + Y L + A D G P +S + Sbjct: 1406 S---TG---VPFRLDLITGELTLTQPIPSSANI-YSLDIRADDAGSNPQQQSTPFSLAII 1458 Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD-EDNRLHYEIT----GGNTRG 410 ++ Y + E++P GT +VT+ A +D + Y ++ GG +G Sbjct: 1459 ISDGQSSILNYVQNTYTGSVRENQPAGTEIVTVVAQYSDGRSATVRYYVSAVTAGGVDKG 1518 Query: 411 RFSITSQNGRGLITVAQPLDFKQ---ERRYVLTVSATDSGGRSD---TAMVQINITDANN 464 I + G+I LD + V TV A D+ S + V +N+ D N+ Sbjct: 1519 SL-IRASVTNGIIRTDAVLDREDLGGGSSLVATVYAVDTSSSSSHVTSVQVTVNVLDEND 1577 Query: 465 YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524 APVF N PYTAS+ E+ + V V ATD+D ++ I YS+ V F Sbjct: 1578 NAPVFTNGPYTASIRENVASNSPVKTVMATDAD--LDTIIFYSI--------VDGATDLF 1627 Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584 I+ TG I T ++DRE+ + Y L + A DG +L+ TT ++I+++D NDN+PVF Sbjct: 1628 SIDSTTGQIRTRGVVDRESSAVYQLQLQASDG---TLTSTTTIDINLLDENDNDPVFSLS 1684 Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNK 643 Y+ + ED +VG V V ATD D GLNG + Y + + E F +DPA+G R + Sbjct: 1685 TYSFLVPEDEMVGEDVGVVVATDPDAGLNGEVAYSVVEEGAPGEDVFYLDPATGAFRLQQ 1744 Query: 644 ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703 +LD E + + +A D G+ P+SST V+I +ED+ND+ PV+ + + E+ IG Sbjct: 1745 SLDYEVKQHYFMTVMATDKGSSPRSSTATVYINVEDVNDNNPVYNPVDYSEEVPEDVAIG 1804 Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY 763 T++ + A D D G N + +SI GD S F++ +VT+ +LD E P Y Sbjct: 1805 TSVVTLTATDLDSGSNGELQFSIASGDPSQRFTV-----YPNGTIVTIKNLDRE-PESFY 1858 Query: 764 ELVIRAASPPL------WNDVRVEILVTDVNDNAP 792 L + A+ L + +V I+VTD+NDNAP Sbjct: 1859 NLEVVASDMTLDPEDRRSSTAQVSIIVTDINDNAP 1893 Score = 321 bits (788), Expect = 2e-85 Identities = 274/892 (30%), Positives = 414/892 (46%), Gaps = 70/892 (7%) Query: 2 SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 S+ + IN+ DCND+SP+F + E G V+ + A+D D G N EV ++ Sbjct: 1233 SLQAVVSMVINIRDCNDNSPIFAYVGVP-EIDEEKPEGFEVVRVSASDSDSGVNGEVRFS 1291 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREK----VARYTVLV 117 I + P D F ID SG + T + +DRE ++ + V Sbjct: 1292 IS-----SQRPSG-------------DFFAIDPESGWITTNSRIDRESEIMATDQFILTV 1333 Query: 118 KATDQASPVSDRLSSTATIHVNIIDDNDNYPQF-SEKTYTVSVDEDISVTDNPVIAKIKA 176 TD A PV R ++T + + + D NDN P+F S++ +S S + N + + A Sbjct: 1334 HGTDLAVPVESRRTATVDVVIFVRDINDNAPRFTSQQAAAIS----RSTSANTRVTTVHA 1389 Query: 177 TDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS 236 D D G N + Y +I +T + F +D ++G+++L + + Y L IRA D GS Sbjct: 1390 DDPDTGVNGQVTYTLI--STGVPFRLDLITGELTLTQPIP-SSANIYSLDIRADDAGSNP 1446 Query: 237 RSNTT--QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294 + +T L I I D + + + + SV EN P G IV V A +D G +A + Y Sbjct: 1447 QQQSTPFSLAIIISDGQSSILNYVQNTYTGSVRENQPAGTEIVTVVAQYSD-GRSATVRY 1505 Query: 295 TMTDKDYTGNVDLP--ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352 ++ G VD I +G + T LDRE LV D S++ Sbjct: 1506 YVSAVT-AGGVDKGSLIRASVTNGIIRTDAVLDREDLGGGSSLVATVYAVDTSSSSSHVT 1564 Query: 353 XXXXX----XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT 408 F G Y + E+ +PV T+ ATDAD D + Y I G T Sbjct: 1565 SVQVTVNVLDENDNAPVFTNGPYTASIRENVASNSPVKTVMATDADLDTIIFYSIVDGAT 1624 Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468 FSI S G+ I +D + Y L + A+D G + T + IN+ D N+ PV Sbjct: 1625 -DLFSIDSTTGQ--IRTRGVVDRESSAVYQLQLQASD-GTLTSTTTIDINLLDENDNDPV 1680 Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528 F + Y+ V ED +G V VV ATD D G+N ++ YS+ E A + F ++P Sbjct: 1681 FSLSTYSFLVPEDEMVGEDVGVVVATDPDAGLNGEVAYSVVEE-----GAPGEDVFYLDP 1735 Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588 TGA + LD E Y +TV A D G S T V I+V DVNDN PV+ Y+ Sbjct: 1736 ATGAFRLQQSLDYEVKQHYFMTVMATDKGSSPRSSTATVYINVEDVNDNNPVYNPVDYSE 1795 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648 + ED +GTSV + ATD D G NG + + + D + F + P +G I T K LDRE Sbjct: 1796 EVPEDVAIGTSVVTLTATDLDSGSNGELQFSIASGDPSQ-RFTVYP-NGTIVTIKNLDRE 1853 Query: 649 SVATHDLKAVAIDGGTPPQ---SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 + ++L+ VA D P+ SST V I + DIND+ P F + + I+E++ Sbjct: 1854 PESFYNLEVVASDMTLDPEDRRSSTAQVSIIVTDINDNAPRFTNPD-SVEIAEDTRTNVI 1912 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765 I +RA D D N+ V Y + F++ +G+ ++ +D + ES Y L Sbjct: 1913 IMVLRAEDDDVERNSYVEYYLL--TPGVPFAVSRVEGN--MQVTGPLDRETES---SYAL 1965 Query: 766 VIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDA 821 +++A +PP + + + I +TDVNDNAP +D PVG F +V A D Sbjct: 1966 LVQATDKGTPPQSSTMNLTIYITDVNDNAPAFSMTPYEATLDEDT-PVGLEFLKVTASDP 2024 Query: 822 D--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 D + ++Y I SG++ ++ TG ++++ LN T+ V D Sbjct: 2025 DEGLNSIIRYSIFSGDSGRAFAIDPVTGVLSVNSGLNYEQRSSYTLTVRAQD 2076 Score = 310 bits (760), Expect = 5e-82 Identities = 243/805 (30%), Positives = 385/805 (47%), Gaps = 47/805 (5%) Query: 98 ALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTV 157 +L+T + LDRE Y + + ATD +S + ++V I D NDN P F++ TY Sbjct: 43 SLVTNSLLDRETEDFYILNISATDNSSTPR---TGYLIVNVTITDVNDNSPIFTQTTYFA 99 Query: 158 SVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDY 217 +V+E S + + ATD D G+N I Y + T F++D +G ++L++ L Y Sbjct: 100 TVNE--SSAAGTSVVHLNATDIDQGSNGDIVYRLKNELTD-NFALDPDTGWITLLRQLPY 156 Query: 218 EQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ------ESVSENVP 271 Y + A D GSPS+S++ + + + D ND++P + + S+SE + Sbjct: 157 -VANGYLFEVTATDKGSPSQSSSAFVNVMVEDENDHSPVIEVLIPEIEASGVASISETML 215 Query: 272 IGYSIVRVQAYDADEGVNAELTYTM---TDK-DYTG-NVDLPITIDPRSGWVYTSGQLDR 326 G + ++A D D N ++ ++ D+ D++G ++ LP V S +DR Sbjct: 216 PG-PLFNLKAIDEDREENGRVSMSIHSGNDRNDFSGTSISLPTGDVFFLLRVSPSANIDR 274 Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386 E A Y L A D G PPR + F+ Y L E G+ V Sbjct: 275 EIIASYNLTFAAEDMGTPPRRTYRSIIIYVVDENDHAPMFLQESYRAGLLESIQVGSFVK 334 Query: 387 TLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444 ++TATDADE + + Y IT G+ G F I NG GL+T + LD + + LT++A+ Sbjct: 335 SVTATDADEGINADIVYSIT-GDEYGWFQI--DNGTGLVTTREKLDHETAAQVTLTITAS 391 Query: 445 DSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502 D G ++T ++ I+I D N+ PVF Y+ +V E++P ++ V ATD D G+N Sbjct: 392 DQGLEPMANTTILTIDIQDVNDEYPVFNQIAYSETVEENSP-ARDLIQVLATDLDNGVNG 450 Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 +TY+ SS+ + F ++P++G + LDRE Y L + A DGG PSL Sbjct: 451 DVTYTFSSD-------QYSGMFSLDPESGLLQITVPLDREEQDSYELEILASDGGSPSLQ 503 Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP 622 T V I+V+D NDN P F Y A+++E+ G V+ V ATD DVG+NG + + L Sbjct: 504 ATATVTIAVLDQNDNPPQFYPTEYYASVIENGPAGLFVTVVSATDLDVGVNGAVIFSLS- 562 Query: 623 KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND 682 + F ID SG + T ++LDRE +++ L A DG + + + + + D D Sbjct: 563 ---DSSKFQIDSYSGNVTTRESLDREQESSYTLTVTAQDGSGQAAAQSATIFVTVTDTLD 619 Query: 683 SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 +P FE + F + EN P T +G + A D N + Y I GD + F ++ G Sbjct: 620 NPLEFELNPYRFQLEENRPNRTEVGTVLATSMD--LNVEITYVIVNGDPNGLFVIDFYSG 677 Query: 743 SDKAELVTMVDLDYESPRK-KYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801 K T + +D E+ + L + A VEI + D+NDNAPV + Sbjct: 678 VIK----TTLSIDREAHESASFRLTVLAVDGSQNGQTVVEIEILDINDNAPVFALPEDQV 733 Query: 802 NNYKDCFPVGPFGRVPAYDAD-VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVP 860 + ++ F DAD + + LS N + +N T+G + L+ L Sbjct: 734 DVVENWAVGNKFYAAQVTDADSPPNNVILYDLSVNFDDRFGINHTSGVLFLNKDLQNYPE 793 Query: 861 KLATMEVSVTD-GVNEIKAMMQLSV 884 K +++ TD G + + M L V Sbjct: 794 KEYNLQIQATDYGTPPLSSSMNLLV 818 Score = 306 bits (751), Expect = 6e-81 Identities = 262/891 (29%), Positives = 404/891 (45%), Gaps = 67/891 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ VLD ND+ P F Y A++ + G V ++ATD D+ NA + Y+I + DT Sbjct: 2292 RVEVLDVNDNPPRFSPTSYTATLPATSQQGCFVAAIQATDTDLEDNAAIRYSI--TSGDT 2349 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 F +D +G ++T E + Y + + A + AS + Sbjct: 2350 SK------------------FVVDQDTGVVITAQGFTDEN-SPYDLQITAENVASGQNSA 2390 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 ++S + +I ++P T+ S S +N + T +G + Y Sbjct: 2391 VAS-----LRVIFSTASFPDI---TFPFSGTSS-SYGENVMTGMTVTTVTAIGI---VTY 2438 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 +I GGN F + S SG+VS++K LDYE+ +S+ L I A D + S+ +L +++ D Sbjct: 2439 SIAGGNHGEHFGVGSQSGEVSIIKELDYEESKSFSLWIAATDTANTQLSDFVELQVSVLD 2498 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 VNDNAP F S++ SV E +V V A D D N +++Y +T GN + Sbjct: 2499 VNDNAPLFDQSVYFTSVVEEQSGQVQVVSVSATDEDSLSNGDVSYAIT----LGNTNNAF 2554 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 I SG + T+ LDRET A Y L V ATDGG+P +S +A F Sbjct: 2555 DIS-SSGVITTTQPLDRETVASYILTVEATDGGNPSQSGSAIVVVTVTDINDNRMSFTK- 2612 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 Y+ + ED PPGT VVTL TD DE+N + I G F+I G IT+ L Sbjct: 2613 MYDATIPEDAPPGTHVVTLHTTDPDENNLSQFSIEAGGQSSLFAINPITGE--ITLNSSL 2670 Query: 430 DFKQERRYVLTVSATDSGGRSDT-AMVQINITDANNYAPVF-ENAPYTASVFEDAPIGTT 487 DF+ E + L V + D + V +N+ D N+ APVF EN+ T G Sbjct: 2671 DFEDEAVHYLLVKSFDPDSSHEVQTQVLVNVEDTNDNAPVFTENSINTTYPEIFFSSGNV 2730 Query: 488 VLVVSATDSDVGINAQITYSLSSEISN---EAVAHHDQQFVINPQTGAITTNKLLDRETM 544 + VSATD+D G N Q+ Y L + + E + + F + P + + + + D Sbjct: 2731 IATVSATDADDGDNGQVDYILKTMTEHFRVETINNRGWIFPVPPISYIVPSPE--DTSNP 2788 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 + Y +V A D G P+L V I+V N PVF Y + + + T V QV Sbjct: 2789 NTYTFSVFAVDRGTPALYGEASVIITVTQDNSYTPVFATPSYFSPVTANTRSNTRVLQVL 2848 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT-NKALDRESVATHDLKAVAIDGG 663 A D D G N I Y + + E F ++ +G I T +L + T+ L A D G Sbjct: 2849 AVDQDTGSNAAITYSISDGNGTE-KFDVEADTGWILTKGVSLAGDVGITYQLLVKATDNG 2907 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 + V I D ND+ PVF+ D I+E+ +G + +RA D D G N + Sbjct: 2908 NIKKEDETTVTFLITDSNDNAPVFDDDTYRSSIAED--VGGYVATVRAEDDDSGINGEIT 2965 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRAASPPLWNDVRVEI 782 YSI G D+ FS++ G +V++V LD E+ ++++ + A +++ I Sbjct: 2966 YSISGA-DAALFSIDAVSG-----IVSLVGSLDRET-SDEHQIQVTAEDRAMYSQSATAI 3018 Query: 783 L---VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNA 837 L VTDV+DN PV + + +++ P V A DAD +Y I G+ Sbjct: 3019 LIVTVTDVDDNPPVFLPREYRADVFENSPSATPVVTVTATDADTGTNADFEYIISGGDGT 3078 Query: 838 NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLIT 888 + +N TG + L+ K T ++V NE M+ + ++T Sbjct: 3079 DFFTINPETGLILTQGNLDYETGK-TTYHLTVA-ATNEQATMVDYAHVIVT 3127 Score = 303 bits (743), Expect = 6e-80 Identities = 264/865 (30%), Positives = 390/865 (45%), Gaps = 73/865 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT-IELVTADT 69 I V D ND++P F QQ A++ S+ T V T+ A D D G N +V YT I Sbjct: 1354 IFVRDINDNAPRFTSQQ-AAAISRSTSANTRVTTVHADDPDTGVNGQVTYTLISTGVPFR 1412 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L+ +++ +D R+ S +++ +++ + +D S + + Sbjct: 1413 LDLITGELTLTQPIPSSANIYSLDIRAD---DAGSNPQQQSTPFSLAIIISDGQSSILNY 1469 Query: 130 LSSTATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 + +T T V +N P +E T + S T ++ + A D G S IR Sbjct: 1470 VQNTYTGSV-----RENQPAGTEIVTVVAQYSDGRSATVRYYVSAVTAGGVDKG--SLIR 1522 Query: 189 YAIIGG--NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 ++ G T + L G SLV T V S S + Q+ +N Sbjct: 1523 ASVTNGIIRTDAVLDREDLGGGSSLVAT-----------VYAVDTSSSSSHVTSVQVTVN 1571 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + D NDNAP F + S+ ENV + V A DAD ++ + Y++ D G D Sbjct: 1572 VLDENDNAPVFTNGPYTASIRENVASNSPVKTVMATDAD--LDTIIFYSIVD----GATD 1625 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 L +ID +G + T G +DRE+ A YQL + A+DG ++T T F Sbjct: 1626 L-FSIDSTTGQIRTRGVVDRESSAVYQLQLQASDG---TLTSTTTIDINLLDENDNDPVF 1681 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLIT 424 Y + EDE G V + ATD D + + Y + G G Sbjct: 1682 SLSTYSFLVPEDEMVGEDVGVVVATDPDAGLNGEVAYSVVEEGAPGEDVFYLDPATGAFR 1741 Query: 425 VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 + Q LD++ ++ Y +TV ATD G RS TA V IN+ D N+ PV+ Y+ V ED Sbjct: 1742 LQQSLDYEVKQHYFMTVMATDKGSSPRSSTATVYINVEDVNDNNPVYNPVDYSEEVPEDV 1801 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 IGT+V+ ++ATD D G N ++ +S++S Q+F + P G I T K LDRE Sbjct: 1802 AIGTSVVTLTATDLDSGSNGELQFSIAS-------GDPSQRFTVYP-NGTIVTIKNLDRE 1853 Query: 543 TMSGYLLTVTARDGGV---PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 S Y L V A D + S T V I V D+NDN P F + I ED Sbjct: 1854 PESFYNLEVVASDMTLDPEDRRSSTAQVSIIVTDINDNAPRFTNP-DSVEIAEDTRTNVI 1912 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 + + A D DV N + Y L F + G ++ LDRE+ +++ L A Sbjct: 1913 IMVLRAEDDDVERNSYVEYYLLTPG---VPFAVSRVEGNMQVTGPLDRETESSYALLVQA 1969 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 D GTPPQSST+ + I I D+ND+ P F + E++P+G ++ A DPDEG N Sbjct: 1970 TDKGTPPQSSTMNLTIYITDVNDNAPAFSMTPYEATLDEDTPVGLEFLKVTASDPDEGLN 2029 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWN 776 +++ YSI GD +F+++ G L L+YE R Y L +RA + Sbjct: 2030 SIIRYSIFSGDSGRAFAIDPVTG----VLSVNSGLNYEQ-RSSYTLTVRAQDQGYSTQVS 2084 Query: 777 DVRVEILVTDVNDNAPVMKDF---QIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRI 831 V V I V DVNDNAPV +D I+ NN P +V A DAD V + +R+ Sbjct: 2085 SVTVTITVADVNDNAPVFEDSYAPSIMENN----LPNADIVQVRADDADSGVNGMINFRL 2140 Query: 832 LSGNNANLILLNETTGSMTLSPQLN 856 S N L + T+G + ++ L+ Sbjct: 2141 ESDYN-GLFTIGSTSGLIQVTEVLD 2164 Score = 295 bits (723), Expect = 1e-77 Identities = 260/889 (29%), Positives = 401/889 (45%), Gaps = 69/889 (7%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 + Q++VLD ND++P+F+ Y SV E S V+++ ATD+D N +V Y I L Sbjct: 2490 VELQVSVLDVNDNAPLFDQSVYFTSVVEEQSGQVQVVSVSATDEDSLSNGDVSYAITL-- 2547 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 +T N D SG + T LDRE VA Y + V+ATD +P Sbjct: 2548 GNTNNAFDISS------------------SGVITTTQPLDRETVASYILTVEATDGGNPS 2589 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 S +A + V + D NDN F+ K Y ++ ED + + + TD D N+ Sbjct: 2590 Q---SGSAIVVVTVTDINDNRMSFT-KMYDATIPEDAPPGTH--VVTLHTTDPD--ENNL 2641 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 +++I G F+I+ ++G+++L +LD+E + L++++ D S S TQ+L+N Sbjct: 2642 SQFSIEAGGQSSLFAINPITGEITLNSSLDFEDEAVHYLLVKSFDPDS-SHEVQTQVLVN 2700 Query: 247 IRDVNDNAPRFYTSLFQESVSE-NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 + D NDNAP F + + E G I V A DAD+G N ++ Y + V Sbjct: 2701 VEDTNDNAPVFTENSINTTYPEIFFSSGNVIATVSATDADDGDNGQVDYILKTMTEHFRV 2760 Query: 306 DLPITIDPRSGWVYTSGQL--------DRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357 + TI+ R GW++ + D Y V A D G P A+ Sbjct: 2761 E---TINNR-GWIFPVPPISYIVPSPEDTSNPNTYTFSVFAVDRGTPALYGEASVIITVT 2816 Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSIT 415 F Y + + T V+ + A D D + + Y I+ GN +F + Sbjct: 2817 QDNSYTPVFATPSYFSPVTANTRSNTRVLQVLAVDQDTGSNAAITYSISDGNGTEKFDVE 2876 Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAP 473 + G ++T L Y L V ATD+G + D V ITD+N+ APVF++ Sbjct: 2877 ADTG-WILTKGVSLAGDVGITYQLLVKATDNGNIKKEDETTVTFLITDSNDNAPVFDDDT 2935 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 Y +S+ ED +G V V A D D GIN +ITYS+S ++ A+ F I+ +G + Sbjct: 2936 YRSSIAED--VGGYVATVRAEDDDSGINGEITYSISG--ADAAL------FSIDAVSGIV 2985 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593 + LDRET + + VTA D + S S T + ++V DV+DN PVF + Y A++ E+ Sbjct: 2986 SLVGSLDRETSDEHQIQVTAEDRAMYSQSATAILIVTVTDVDDNPPVFLPREYRADVFEN 3045 Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT- 652 + T V V ATDAD G N Y + D + F I+P +G+I T LD E+ T Sbjct: 3046 SPSATPVVTVTATDADTGTNADFEYIISGGDGTD-FFTINPETGLILTQGNLDYETGKTT 3104 Query: 653 -HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711 H A + T + VIV + E N+ P F FY++E++ G +G + A Sbjct: 3105 YHLTVAATNEQATMVDYAHVIVTLLGE--NEFYPQFTQHQYDFYVNEHATDGAPVGVVLA 3162 Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771 D D G + +V+Y GG + F++ G LD E+ V+ Sbjct: 3163 TDDDLGDDGIVNYLFIGGSNLQGFNVNLESGQITVAYEN-GRLDRETADTVLLSVLAKNE 3221 Query: 772 PPLWN-DVRVEILVTDVND--NAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--- 825 P+ D+ ++ VND +APV Q + P V A D D Sbjct: 3222 GPITGADIDEAEVIIHVNDGNDAPVFSSEQYQARVLESEPPGSDVTVVTAADYDEIPSFR 3281 Query: 826 KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN 874 + Y IL GN + ++ TG +T + L+ + + V+ D N Sbjct: 3282 QFNYSILRGNEGDAFHIDARTGRITTASLLDRETLSVYFLTVAAIDTGN 3330 Score = 294 bits (722), Expect = 2e-77 Identities = 240/794 (30%), Positives = 366/794 (46%), Gaps = 70/794 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND++PVFE Y S+ E ++ ++A D D G N + + +E Sbjct: 2090 ITVADVNDNAPVFE-DSYAPSIMENNLPNADIVQVRADDADSGVNGMINFRLE------- 2141 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +F I SG + LD E + ++V A D +P S + Sbjct: 2142 -------------SDYNGLFTIGSTSGLIQVTEVLDYEDQNEFELIVIAEDSGTP-SHQT 2187 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +T T+ VN DDND+ P+F Y +V ED S + + ++ ATD D A +A+RY Sbjct: 2188 RTTMTLTVN--DDNDHDPEFVSDFYRATVSEDASA--DTFVIQVTATDVD--ATAALRYR 2241 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + + +F+ID L G + LD E SY L + DG PSR TT + + + DV Sbjct: 2242 L-NSDIGSKFTIDPLGGRILTTGLLDREVQSSYLLTVTVDDG--PSRLATTSVRVEVLDV 2298 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN PRF + + ++ G + +QA D D NA + Y++T D + V Sbjct: 2299 NDNPPRFSPTSYTATLPATSQQGCFVAAIQATDTDLEDNAAIRYSITSGDTSKFV----- 2353 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 +D +G V T+ E + Y L +TA + SA A+ F Sbjct: 2354 VDQDTGVVITAQGFTDEN-SPYDLQITAENVASGQNSAVASLRVIFSTASFPDITFPFSG 2412 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 E+ G V T+TA + Y I GGN F + SQ+G +++ + LD Sbjct: 2413 TSSSYGENVMTGMTVTTVTAIGI-----VTYSIAGGNHGEHFGVGSQSGE--VSIIKELD 2465 Query: 431 FKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 +++ + + L ++ATD+ SD +Q+++ D N+ AP+F+ + Y SV E+ V Sbjct: 2466 YEESKSFSLWIAATDTANTQLSDFVELQVSVLDVNDNAPLFDQSVYFTSVVEEQSGQVQV 2525 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 + VSATD D N ++Y+++ +N A F I+ +G ITT + LDRET++ Y+ Sbjct: 2526 VSVSATDEDSLSNGDVSYAITLGNTNNA-------FDIS-SSGVITTTQPLDRETVASYI 2577 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 LTV A DGG PS S + V ++V D+NDN F ++Y A I EDA GT V + TD Sbjct: 2578 LTVEATDGGNPSQSGSAIVVVTVTDINDNRMSF-TKMYDATIPEDAPPGTHVVTLHTTDP 2636 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 D N + ++ + F I+P +G I N +LD E A H L + D + + Sbjct: 2637 DE--NNLSQFSIE-AGGQSSLFAINPITGEITLNSSLDFEDEAVHYLLVKSFDPDSSHEV 2693 Query: 669 STVIVHIKIEDINDSPPVF-ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 T ++ + +ED ND+ PVF E+ T Y G I + A D D+G N V Y +K Sbjct: 2694 QTQVL-VNVEDTNDNAPVFTENSINTTYPEIFFSSGNVIATVSATDADDGDNGQVDYILK 2752 Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPR-----KKYELVIRA---ASPPLWNDVR 779 + F +ET V + SP Y + A +P L+ + Sbjct: 2753 --TMTEHFRVETINNRGWIFPVPPISYIVPSPEDTSNPNTYTFSVFAVDRGTPALYGEAS 2810 Query: 780 VEILVTDVNDNAPV 793 V I VT N PV Sbjct: 2811 VIITVTQDNSYTPV 2824 Score = 285 bits (698), Expect = 2e-74 Identities = 252/895 (28%), Positives = 415/895 (46%), Gaps = 86/895 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I VLD ND+ P F+ Y + E G V T+ A D D+G N E+ Y+ T Sbjct: 921 EIIVLDENDNRPFFDNATYNFYLSEEDDIGAAVGTIHAVDNDVGGNGELTYSF------T 974 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR------YTVLVKATDQA 123 N +F ++ +GA+ ++ SLDRE + +++ V+ D Sbjct: 975 AN---------------HTLFTLNSVTGAITSKVSLDRESLVEAGQPTTFSIRVRVHDSG 1019 Query: 124 SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183 P +L A ++++++D ND+ P F+ ++Y SV E + +I ++ ATD DVG Sbjct: 1020 QP---QLQDHADVNIHVVDINDSPPVFNRESYQASVSE--LAQNETLIIRVSATDDDVGD 1074 Query: 184 NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 NS I Y+I+ GN + +F ID + G + L+ LD E Y L ++A+DGG + + ++ Sbjct: 1075 NSYILYSIVSGNEEKRFHIDHVHGQIVLIAPLDREVTEGYVLRVKARDGGIVPQESFVEV 1134 Query: 244 LINIRDVNDNAPRFYTSLFQE-SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 I + D ND+ P F L +E V+E + IG +I VQA D D N +++YT+T Sbjct: 1135 EITVLDENDHRPSFSVDLQREIEVTECLQIGDTIGGVQATDMDINSNGQISYTITG---- 1190 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 GN+D ++ SG VY +G LD E ++Y L +TA DGG P A + Sbjct: 1191 GNLDGVFGVNANSGEVYLTGYLDHEATSQYSLNITARDGGSPSLQAVVSMVINIRDCNDN 1250 Query: 363 XXXF-MPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNG 419 F G E++ E++P G VV ++A+D+D + + + I+ G F Sbjct: 1251 SPIFAYVGVPEID--EEKPEGFEVVRVSASDSDSGVNGEVRFSISSQRPSGDFFAIDPES 1308 Query: 420 RGLITVAQPLDFKQE----RRYVLTVSATD-----SGGRSDTAMVQINITDANNYAPVFE 470 G IT +D + E +++LTV TD R+ T V I + D N+ AP F Sbjct: 1309 -GWITTNSRIDRESEIMATDQFILTVHGTDLAVPVESRRTATVDVVIFVRDINDNAPRF- 1366 Query: 471 NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 + A++ T V V A D D G+N Q+TY+L S F ++ T Sbjct: 1367 TSQQAAAISRSTSANTRVTTVHADDPDTGVNGQVTYTLIST---------GVPFRLDLIT 1417 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV--FKQQLYTA 588 G +T + + + + Y L + A D G +T ++++ + + + Q YT Sbjct: 1418 GELTLTQPIP-SSANIYSLDIRADDAGSNPQQQSTPFSLAIIISDGQSSILNYVQNTYTG 1476 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR---EEGSFV-IDPASGVIRTNKA 644 ++ E+ GT + V A +D G + + Y + ++GS + +G+IRT+ Sbjct: 1477 SVRENQPAGTEIVTVVAQYSD-GRSATVRYYVSAVTAGGVDKGSLIRASVTNGIIRTDAV 1535 Query: 645 LDRESV-ATHDLKAVAIDGGTPPQSS---TVIVHIKIEDINDSPPVFESDCLTFYISENS 700 LDRE + L A T SS +V V + + D ND+ PVF + T I EN Sbjct: 1536 LDREDLGGGSSLVATVYAVDTSSSSSHVTSVQVTVNVLDENDNAPVFTNGPYTASIRENV 1595 Query: 701 PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760 + + + A D D + ++ YSI G ++ FS+++ G ++ T +D ES Sbjct: 1596 ASNSPVKTVMATDAD--LDTIIFYSIVDG-ATDLFSIDSTTG----QIRTRGVVDRES-S 1647 Query: 761 KKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD 820 Y+L ++A+ L + ++I + D NDN PV F +D G V A D Sbjct: 1648 AVYQLQLQASDGTLTSTTTIDINLLDENDNDPVFSLSTYSFLVPEDEMVGEDVGVVVATD 1707 Query: 821 AD--VTDKLQYRIL--SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 D + ++ Y ++ ++ L+ TG+ L L+ V + M V TD Sbjct: 1708 PDAGLNGEVAYSVVEEGAPGEDVFYLDPATGAFRLQQSLDYEVKQHYFMTVMATD 1762 Score = 257 bits (629), Expect = 4e-66 Identities = 211/700 (30%), Positives = 333/700 (47%), Gaps = 49/700 (7%) Query: 209 VSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266 VSLV LD E Y L I A D S R+ + + I DVNDN+P F + + +V Sbjct: 42 VSLVTNSLLDRETEDFYILNISATDNSSTPRTGYLIVNVTITDVNDNSPIFTQTTYFATV 101 Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326 +E+ G S+V + A D D+G N ++ Y + + + T N +DP +GW+ QL Sbjct: 102 NESSAAGTSVVHLNATDIDQGSNGDIVYRLKN-ELTDN----FALDPDTGWITLLRQLPY 156 Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE------LAEDEP 380 Y VTATD G P +S++A E+E ++E Sbjct: 157 VANG-YLFEVTATDKGSPSQSSSAFVNVMVEDENDHSPVIEVLIPEIEASGVASISETML 215 Query: 381 PGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQN-GRG----LITVAQPLDFKQ 433 PG P+ L A D D E+ R+ I GN R FS TS + G L+ V+ + + Sbjct: 216 PG-PLFNLKAIDEDREENGRVSMSIHSGNDRNDFSGTSISLPTGDVFFLLRVSPSANIDR 274 Query: 434 E--RRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 E Y LT +A D G R + I + D N++AP+F Y A + E +G+ V Sbjct: 275 EIIASYNLTFAAEDMGTPPRRTYRSIIIYVVDENDHAPMFLQESYRAGLLESIQVGSFVK 334 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 V+ATD+D GINA I YS++ + F I+ TG +TT + LD ET + L Sbjct: 335 SVTATDADEGINADIVYSITGD--------EYGWFQIDNGTGLVTTREKLDHETAAQVTL 386 Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 T+TA D G+ +++TT + I + DVND PVF Q Y+ + E++ + QV ATD D Sbjct: 387 TITASDQGLEPMANTTILTIDIQDVNDEYPVFNQIAYSETVEENS-PARDLIQVLATDLD 445 Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669 G+NG + Y D+ G F +DP SG+++ LDRE +++L+ +A DGG+P + Sbjct: 446 NGVNGDVTYTFS-SDQYSGMFSLDPESGLLQITVPLDREEQDSYELEILASDGGSPSLQA 504 Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729 T V I + D ND+PP F + EN P G + + A D D G N V +S+ Sbjct: 505 TATVTIAVLDQNDNPPQFYPTEYYASVIENGPAGLFVTVVSATDLDVGVNGAVIFSL--- 561 Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTD 786 DS+ F +++ G+ + T LD E Y L + A + + + VTD Sbjct: 562 SDSSKFQIDSYSGN----VTTRESLDREQ-ESSYTLTVTAQDGSGQAAAQSATIFVTVTD 616 Query: 787 VNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETT 846 DN + F ++ G V A D+ ++ Y I++G+ L +++ + Sbjct: 617 TLDNPLEFELNPYRFQLEENRPNRTEVGTVLATSMDLNVEITYVIVNGDPNGLFVIDFYS 676 Query: 847 GSMTLSPQLNTNVPKLATMEVSV--TDGVNEIKAMMQLSV 884 G + + ++ + A+ ++V DG + ++++ + Sbjct: 677 GVIKTTLSIDREAHESASFRLTVLAVDGSQNGQTVVEIEI 716 Score = 133 bits (322), Expect = 6e-29 Identities = 146/585 (24%), Positives = 241/585 (41%), Gaps = 100/585 (17%) Query: 1001 ICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILT 1060 ICV P N E+C + +++ +NS+ + F C+C G++GV CE Sbjct: 3728 ICVCAPGYNGEDCKVEINECSSNPCINSECQDL-----INGFYCECSTGYSGVYCENGPC 3782 Query: 1061 KASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCELRARSFPVSSFLTFPG 1120 S V+G GS SGS V C ++ C+ F S+++ Sbjct: 3783 STSPCVNG-GSCVESGSTFV-----------CQCGNSHWGNRCQYDTIGFQAGSYISSSA 3830 Query: 1121 LKRRHRIHLKLKFATQTTSGLLLYN--GRYNERHDFLALELVSSEAGRGGGPGLRFSFSL 1178 L+ + L L+F+T +T LL YN + F+ALE++ GR L+ SF+ Sbjct: 3831 LQSTSAVIL-LEFSTVSTKALLFYNHDSFTDSNAKFVALEILD---GR-----LQLSFNF 3881 Query: 1179 GGGKSEITVEGNVGDGSWHTVEIEYFNRTITM-ILD-DCDKVLSLAGAADFGLKYACANF 1236 G G++ I+ V DG+WH VE+ ++ + ILD DC + + A Sbjct: 3882 GSGQNSISASKPVSDGAWHKVEVRLEGMSVDLNILDEDCPSLSTDA-------------- 3927 Query: 1237 TRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPS----SFQVKNKDFVGCISDFYIDH 1292 C ET PL +GG+ +I + QV DFVGC++ ++ Sbjct: 3928 --------CRASQETTISLAFDNNPLTVGGVSDIAEITSRASQVSAADFVGCMNSIEVNG 3979 Query: 1293 KFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADST 1352 + + +++ + + GC R C C +G+ C D W CDC E +G CA+ Sbjct: 3980 ERLSMSNARDHSNLVEGC--IREGCGETSCSDGSVCVDDWWKTWCDCDEMASGATCAEDN 4037 Query: 1353 GPPWRFGGDGMLSF---NPLLRPIQLPWLNALSIRTRQR--------------------- 1388 FGG G + + R L L+ R R+R Sbjct: 4038 NSV-SFGGGGRVDYTVKEDYKRQALLDDAKVLTRRRRRRASGSETVSLSFRTGVKDGLLL 4096 Query: 1389 ----DAFVMSIQLKSGLLHYSY------NGETMYLPMATLSDGAWHRIEIKWLGTDISVT 1438 DA ++QL +G + YSY +G+ + +P ++L+DGAWH I + G +++T Sbjct: 4097 YVTSDAEFTALQLSNGSVMYSYGSGSSSSGQIINIPSSSLTDGAWHNITLTSAGGQVTLT 4156 Query: 1439 VDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGLLASDVGFFEGCIQDVRIGTAQSLL 1498 VD ++ + ++ G + + +GG +T + + F GC+ ++ L Sbjct: 4157 VDNAPKSAMFAD-PHEFTGLGLTGMALGGAETPLVINGRSIEGFTGCLDGFQMNGEGLPL 4215 Query: 1499 NRPTVR------ENVRDGCQSRADCMLSICPPYSKCVTSWDSSTC 1537 + + R +GC C L+ C CV S TC Sbjct: 4216 DGDSQRFEAVPSAGTGEGCSPADLCALNPCSQGEACVPSETYYTC 4260 Score = 130 bits (315), Expect = 4e-28 Identities = 109/358 (30%), Positives = 163/358 (45%), Gaps = 22/358 (6%) Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589 T ++ TN LLDRET Y+L ++A D + V +++ DVNDN P+F Q Y A Sbjct: 41 TVSLVTNSLLDRETEDFYILNISATDNSSTPRTGYLIVNVTITDVNDNSPIFTQTTYFAT 100 Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES 649 + E + GTSV + ATD D G NG I Y L K+ +F +DP +G I + L + Sbjct: 101 VNESSAAGTSVVHLNATDIDQGSNGDIVYRL--KNELTDNFALDPDTGWITLLRQLPYVA 158 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT---- 705 + + A D G+P QSS+ V++ +ED ND PV E S + I T Sbjct: 159 NG-YLFEVTATDKGSPSQSSSAFVNVMVEDENDHSPVIEVLIPEIEASGVASISETMLPG 217 Query: 706 -IGEIRAHDPDEGPNAVVHYSIKGGDDSNSF-----SLETRQGSDKAELVTMVDLDYESP 759 + ++A D D N V SI G+D N F SL T + ++D E Sbjct: 218 PLFNLKAIDEDREENGRVSMSIHSGNDRNDFSGTSISLPTGDVFFLLRVSPSANIDREI- 276 Query: 760 RKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR- 815 Y L A +PP + I V D ND+AP+ + + VG F + Sbjct: 277 IASYNLTFAAEDMGTPPRRTYRSIIIYVVDENDHAPMFLQ-ESYRAGLLESIQVGSFVKS 335 Query: 816 VPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 V A DAD + + Y I +G+ ++ TG +T +L+ T+ ++ +D Sbjct: 336 VTATDADEGINADIVYSI-TGDEYGWFQIDNGTGLVTTREKLDHETAAQVTLTITASD 392 Score = 78.6 bits (185), Expect = 2e-12 Identities = 83/374 (22%), Positives = 150/374 (40%), Gaps = 35/374 (9%) Query: 1205 NRTITMILDDCDKVLSLAGAADFGLKYAC-ANFTRKVLPARCEIPTETCHRFLDLTGPL- 1262 N + ++ + D V+ + AC A F+ + RCEIPT+ C + G Sbjct: 3665 NINLEELITESDPVIFVGLQTSHSFTCACPAEFSGQ----RCEIPTDYCGQATCKNGATC 3720 Query: 1263 --QIGGLPNIPS---SFQVKNKDFVGCISDFYIDHKFIDL-NSYVADNGT-LAGCPEKRS 1315 IGG + + + + + C S+ I+ + DL N + + T +G + Sbjct: 3721 QNAIGGYICVCAPGYNGEDCKVEINECSSNPCINSECQDLINGFYCECSTGYSGVYCENG 3780 Query: 1316 RCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCA-DSTG-PPWRFGGDGMLSFNPLLRPI 1373 CS++PC NG C + T++C C H G C D+ G + L + + Sbjct: 3781 PCSTSPCVNGGSCVESGSTFVCQCGNSHWGNRCQYDTIGFQAGSYISSSALQSTSAVILL 3840 Query: 1374 QLPWLNALSIRTRQRDAFV------MSIQLKSGLLHYSYN---GETMYLPMATLSDGAWH 1424 + ++ ++ D+F +++++ G L S+N G+ +SDGAWH Sbjct: 3841 EFSTVSTKALLFYNHDSFTDSNAKFVALEILDGRLQLSFNFGSGQNSISASKPVSDGAWH 3900 Query: 1425 RIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYI------GKILIGGLDTTAGLL--A 1476 ++E++ G + + + L Q I + +GG+ A + A Sbjct: 3901 KVEVRLEGMSVDLNILDEDCPSLSTDACRASQETTISLAFDNNPLTVGGVSDIAEITSRA 3960 Query: 1477 SDVGF--FEGCIQDVRIGTAQSLLNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDS 1534 S V F GC+ + + + ++ N+ +GC R C + C S CV W Sbjct: 3961 SQVSAADFVGCMNSIEVNGERLSMSNARDHSNLVEGC-IREGCGETSCSDGSVCVDDWWK 4019 Query: 1535 STCTCEAGRVGPQC 1548 + C C+ G C Sbjct: 4020 TWCDCDEMASGATC 4033 Score = 40.7 bits (91), Expect = 0.57 Identities = 16/38 (42%), Positives = 20/38 (52%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGP 1354 C C NG CSD + C+C EG++G C TGP Sbjct: 4265 CVPDVCLNGGVCSDGTGSVTCECAEGYSGDYCEGGTGP 4302 >UniRef50_Q4SFW8 Cluster: Chromosome 7 SCAF14601, whole genome shotgun sequence; n=4; Eumetazoa|Rep: Chromosome 7 SCAF14601, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 2970 Score = 394 bits (969), Expect = e-107 Identities = 397/1411 (28%), Positives = 617/1411 (43%), Gaps = 140/1411 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ +LD ND++P+FE Y A+V EG GT V+ ++A D D G N +V Y +E ++D Sbjct: 1549 EVKILDVNDNNPLFETNTYVATVMEGMPIGTRVVQVRALDPDWGANGQVCY-VEAASSD- 1606 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 P + VF ID ++G + T + +D E + Y+ V A+D S Sbjct: 1607 -GPITSSS-----------VFAIDSKTGWITTVSEMDHEACSSYSFEVVASDLGELRS-- 1652 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSAIR 188 LSST + + + D NDN P+F + Y +V E S+ + V+A +K +D D N + Sbjct: 1653 LSSTTVVTIAVSDCNDNPPRFERELYRGAVKESDSLGE--VVAVLKTSDRDGTDQNRLVS 1710 Query: 189 YAIIGGNTQMQFSIDSLSGD--VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 + I GGN + F + + G+ V + LD EQ Y L I A DG + T + + Sbjct: 1711 FYISGGNPRGVFGLAPVQGEWKVYVSGLLDREQQDWYLLNITASDGLYVAH---TAVEVT 1767 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + D NDN P +++ S E++P+ I+ V A DAD G +AE+ Y++ G D Sbjct: 1768 VMDANDNRPICNQAVYSASFPEDIPVNKGILTVAATDADSGSSAEIQYSLFG---IGVED 1824 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 +D +G + T+ +DRET Y+L+ ATDGG + F Sbjct: 1825 F--YMDANTGELRTATIMDRETTPSYKLIAQATDGGG--LFCRSDISLKVLDVNDNAPTF 1880 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 Y + E+ P + L A+D DE T + FSI +G ++ + Sbjct: 1881 SSPHYLASVYENAAPKALLTRLQASDPDEGLNRTLVYTLDSIDELFSIDPVSG--MVVLE 1938 Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT----DANNYAPVFENAPYTASVFEDA 482 + LD + + Y L V ATD G+ Q+N+T D N+ APVF+ Y +V ED Sbjct: 1939 KSLDRESQDSYRLRVQATDQAGQRGALSTQVNLTILVLDVNDNAPVFQRRDYGVTVPEDV 1998 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 +GT VL V AT D+G+NA+I+Y + S NE +F I+ G+I LD E Sbjct: 1999 AVGTEVLRVLATSVDIGLNAEISYRIRS--GNEL-----GKFNIDTNLGSIFVADDLDFE 2051 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 Y LT+ A DGG P LS T V I ++DVNDN P F Q +Y + EDA VG V++ Sbjct: 2052 VCKDYYLTIEAWDGGNPPLSSATVVTIDLMDVNDNAPTFSQDIYNVLVSEDASVGQMVTR 2111 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 V A D D NGRI Y + DR F IDP +G+++ NK LDRE V+ + L A D Sbjct: 2112 VSAEDLDSQGNGRITYSILKGDR-NNHFWIDPVTGILKVNKRLDRELVSRYSLSVQAFDS 2170 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESD-------------CLTF---YISENSPI---- 702 G+P SSTV ++I I DIND+ PVF L F YIS P+ Sbjct: 2171 GSPAMSSTVTLNIDISDINDNSPVFTPPNSTAIIQVPAPALLLVFVRSYISLPPPLSHLQ 2230 Query: 703 -----GTTIGEIRAHDPDEGPNA-VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756 G+T+ ++ D D N + I G++ N FSL+ + G+ K+ V D Sbjct: 2231 LNQAAGSTLLKLSVSDKDSPKNGPPFDFRIVSGNEENFFSLD-QAGTLKSNRV----FDP 2285 Query: 757 ESPRK-KYEL-VIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG 814 E+PR+ E+ V + P L V + V + P++ +I D FP GP G Sbjct: 2286 EAPREFTLEIQVSDSGKPRLAASSWVFLRVIGNSQYKPLVSPLEIFIVMATDTFPGGPIG 2345 Query: 815 RVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN 874 R+ A D D D L + + ++ +N G++ P L P + +V+DG Sbjct: 2346 RIYATDRDPNDVLSF-TQKLQSKSMFKINRQDGTVVAVPGLE---PGRYQINATVSDGRF 2401 Query: 875 EIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLL---GFFIDGLAA--IIPCPKE 929 + A + + V +T+ +L +++T+R + ++ E L L + GLA P ++ Sbjct: 2402 AVIADVSVQVEQVTDVLLRSALTLRFSSLSPEDLLGRYLRQIKLILRGLAGWKWSPGQQD 2461 Query: 930 NIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERV-YLHRTTLAR 988 ++I S++ + +G +++ + RP E +G YS L ++ + L R Sbjct: 2462 PLHIISLKPVSGTSG--VDLLLAMERP--ETAGSGRIGGFYSQQELTVKLEEAAQRGLIR 2517 Query: 989 LATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFV-NSDSVLFRPIYPVTSFTCQCP 1047 + C + C L S +++ V + T+ C CP Sbjct: 2518 GVLAGAVAVGSTCSGELECGDSLVCEQKLVMEEGSPLTYSTERVSLVSLAFGTTEACTCP 2577 Query: 1048 EGF--TGVN-CETILTKASCEVDGDGSICRSGSQCVARR----EGGILCQGCSIDAAYTT 1100 G T V CE A + G S QC+ R G ++ + + Sbjct: 2578 GGACPTPVELCEGQSCPADMQCVRSGPTAPSVCQCLPERLDQCAGAVISSSLYLGSNSNV 2637 Query: 1101 A--------VCELRARSFPVSSFLTF--PGLKRRHRIHLKLKFATQTTSGLLLYNGRYNE 1150 V + + SF +S++ + + + L L+ T G+++Y R N Sbjct: 2638 TKNFKSDLLVTDQTSLSFSGNSYIKYRVSDGGQNGEMKLSLRIRTLQRRGVIMYT-RVN- 2695 Query: 1151 RHDFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGN-VGDGSWHTVEIEYFNRTIT 1209 ++ E GR L F + + + DG WH V +E + Sbjct: 2696 -----PCTMLKIEGGR-----LWFQLDCDNTLGIMGISDRPINDGLWHAVALELTSNYTL 2745 Query: 1210 MILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPN 1269 + LDD A A L + A + A+ P+ + GP + G P Sbjct: 2746 LSLDDSYVERRRAARAPVRL-WPLAPDSSFFFGAQVRPPSVQGEK----PGPGRTQGGPA 2800 Query: 1270 IPSS---FQVKNK-DFVGCISDFYIDHKFIDLNSYVADNGTLA-------GCPEKRSRCS 1318 + S Q K + F GC+ ++ + L + + +A GC C Sbjct: 2801 LGDSGTRSQPKAQGGFQGCLGSLMLNGNELPLQNKRSRYAEIAGLSDVKLGCVLYPDPCV 2860 Query: 1319 SAPCYNGAECSDL-WDTYICDCKEGHTGKDC 1348 S PC NGA CS L + C C G TG C Sbjct: 2861 SQPCLNGAMCSSLPSGGFACSCSAGFTGARC 2891 Score = 359 bits (882), Expect = 8e-97 Identities = 277/882 (31%), Positives = 428/882 (48%), Gaps = 57/882 (6%) Query: 5 FCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIEL 64 FC + I + D ND+ P F +Y S++ + G+ V ++A+D D G N + Y+ L Sbjct: 1330 FCSVRVI-LADENDNPPRFRAVEYRMSIKANVAKGSLVTQIQASDPDAGSNGRITYS--L 1386 Query: 65 VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS 124 + L+ D V +V R SG ++T++++D + + VKATD S Sbjct: 1387 YSEARLSLVD-----------VLEVSRF--YSGWMMTKSNVDHLQGTVLSFFVKATDSGS 1433 Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184 P L S A IHV + + P FS+ Y+ ++ ED V + + G Sbjct: 1434 PAKHSLVS-AFIHV--VPPDAFVPSFSQPQYSFTIPEDTVV--GTALGSVYMGPGQTGFF 1488 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT-QL 243 +A+ ++ N F +D SG + L K LDYE+V +R + + TT L Sbjct: 1489 TAVVGEMVDSNQGGTFLVDRESGLIRLSKPLDYEEVSIFRFKVAVTTRRDLIEAVTTVDL 1548 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT-MTDKDYT 302 + I DVNDN P F T+ + +V E +PIG +V+V+A D D G N ++ Y D Sbjct: 1549 EVKILDVNDNNPLFETNTYVATVMEGMPIGTRVVQVRALDPDWGANGQVCYVEAASSDGP 1608 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD-PPRSATATXXXXXXXXXX 361 ID ++GW+ T ++D E + Y V A+D G+ S+T Sbjct: 1609 ITSSSVFAIDSKTGWITTVSEMDHEACSSYSFEVVASDLGELRSLSSTTVVTIAVSDCND 1668 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRL-HYEITGGNTRGRFSITSQN 418 F Y + E + G V L +D D + NRL + I+GGN RG F + Sbjct: 1669 NPPRFERELYRGAVKESDSLGEVVAVLKTSDRDGTDQNRLVSFYISGGNPRGVFGLAPVQ 1728 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASV 478 G + V+ LD +Q+ Y+L ++A+D + TA V++ + DAN+ P+ A Y+AS Sbjct: 1729 GEWKVYVSGLLDREQQDWYLLNITASDGLYVAHTA-VEVTVMDANDNRPICNQAVYSASF 1787 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 ED P+ +L V+ATD+D G +A+I YSL I E F ++ TG + T + Sbjct: 1788 PEDIPVNKGILTVAATDADSGSSAEIQYSLFG-IGVE-------DFYMDANTGELRTATI 1839 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 +DRET Y L A DGG L +D+ + V+DVNDN P F Y A++ E+A Sbjct: 1840 MDRETTPSYKLIAQATDGG--GLFCRSDISLKVLDVNDNAPTFSSPHYLASVYENAAPKA 1897 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 ++++ A+D D GLN + Y LD D F IDP SG++ K+LDRES ++ L+ Sbjct: 1898 LLTRLQASDPDEGLNRTLVYTLDSIDE---LFSIDPVSGMVVLEKSLDRESQDSYRLRVQ 1954 Query: 659 AID--GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 A D G S+ V + I + D+ND+ PVF+ + E+ +GT + + A D Sbjct: 1955 ATDQAGQRGALSTQVNLTILVLDVNDNAPVFQRRDYGVTVPEDVAVGTEVLRVLATSVDI 2014 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPP 773 G NA + Y I+ G++ F+++T GS + DLD+E K Y L I A +PP Sbjct: 2015 GLNAEISYRIRSGNELGKFNIDTNLGS----IFVADDLDFE-VCKDYYLTIEAWDGGNPP 2069 Query: 774 LWNDVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVGPF-GRVPAYDADV--TDKLQY 829 L + V I + DVNDNAP Q I+N + VG RV A D D ++ Y Sbjct: 2070 LSSATVVTIDLMDVNDNAPTFS--QDIYNVLVSEDASVGQMVTRVSAEDLDSQGNGRITY 2127 Query: 830 RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 IL G+ N ++ TG + ++ +L+ + ++ V D Sbjct: 2128 SILKGDRNNHFWIDPVTGILKVNKRLDRELVSRYSLSVQAFD 2169 Score = 307 bits (754), Expect = 3e-81 Identities = 227/720 (31%), Positives = 343/720 (47%), Gaps = 45/720 (6%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F +D SG + LD E+V+ + V T + + +T + V I+D NDN P Sbjct: 1504 FLVDRESGLIRLSKPLDYEEVSIFRFKVAVTTRRDLIE--AVTTVDLEVKILDVNDNNPL 1561 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN-----TQMQFSIDS 204 F TY +V E + + + +++A D D GAN + Y + + F+IDS Sbjct: 1562 FETNTYVATVMEGMPIGTR--VVQVRALDPDWGANGQVCYVEAASSDGPITSSSVFAIDS 1619 Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGS-PSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263 +G ++ V +D+E SY + A D G S S+TT + I + D NDN PRF L++ Sbjct: 1620 KTGWITTVSEMDHEACSSYSFEVVASDLGELRSLSSTTVVTIAVSDCNDNPPRFERELYR 1679 Query: 264 ESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYTGNVDLPITIDPRSG-W-VYT 320 +V E+ +G + ++ D D N +++ ++ GN + P G W VY Sbjct: 1680 GAVKESDSLGEVVAVLKTSDRDGTDQNRLVSFYISG----GNPRGVFGLAPVQGEWKVYV 1735 Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380 SG LDRE Q Y L +TA+DG +A + Y ED P Sbjct: 1736 SGLLDREQQDWYLLNITASDGLYVAHTAVEVTVMDANDNRPICNQAV---YSASFPEDIP 1792 Query: 381 PGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYV 438 ++T+ ATDAD + + Y + G F + + G + A +D + Y Sbjct: 1793 VNKGILTVAATDADSGSSAEIQYSLFGIGVED-FYMDANTGE--LRTATIMDRETTPSYK 1849 Query: 439 LTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498 L ATD GG + + + + D N+ AP F + Y ASV+E+A + + A+D D Sbjct: 1850 LIAQATDGGGLFCRSDISLKVLDVNDNAPTFSSPHYLASVYENAAPKALLTRLQASDPDE 1909 Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD--G 556 G+N + Y+L S D+ F I+P +G + K LDRE+ Y L V A D G Sbjct: 1910 GLNRTLVYTLDSI---------DELFSIDPVSGMVVLEKSLDRESQDSYRLRVQATDQAG 1960 Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616 +LS ++ I V+DVNDN PVF+++ Y + ED VGT V +V AT D+GLN I Sbjct: 1961 QRGALSTQVNLTILVLDVNDNAPVFQRRDYGVTVPEDVAVGTEVLRVLATSVDIGLNAEI 2020 Query: 617 HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676 Y + E G F ID G I LD E + L A DGG PP SS +V I Sbjct: 2021 SYRIR-SGNELGKFNIDTNLGSIFVADDLDFEVCKDYYLTIEAWDGGNPPLSSATVVTID 2079 Query: 677 IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736 + D+ND+ P F D +SE++ +G + + A D D N + YSI GD +N F Sbjct: 2080 LMDVNDNAPTFSQDIYNVLVSEDASVGQMVTRVSAEDLDSQGNGRITYSILKGDRNNHFW 2139 Query: 737 LETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPV 793 ++ G K +D + S +Y L ++A SP + + V + I ++D+NDN+PV Sbjct: 2140 IDPVTGILKVN--KRLDRELVS---RYSLSVQAFDSGSPAMSSTVTLNIDISDINDNSPV 2194 Score = 267 bits (654), Expect = 3e-69 Identities = 243/905 (26%), Positives = 399/905 (44%), Gaps = 86/905 (9%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72 VLD ND++P+F+ Y + + E GTTVL + A DQD KNA V Y I +D N Sbjct: 994 VLDVNDNAPLFQNTSYSSVLPENVMIGTTVLKVFAQDQDSEKNAIVSYQI---LSDIYNS 1050 Query: 73 EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132 D F ID SG + LD E V R+ +V+ATD P LSS Sbjct: 1051 TD--------------YFHIDSSSGLIFMARRLDYELVQRHNFIVRATDSGDPT---LSS 1093 Query: 133 TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192 ++ V + D NDN P FS+ Y V E ++ D+ + ++A+DAD+ +RY+I+ Sbjct: 1094 DVSVTVTVTDTNDNPPNFSQTLYEAFVSE-LAPRDH-FVTCVQASDADICDAQRLRYSIV 1151 Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252 GN +M F ++ +G + L SY+L + DG +NT Q+++ + N Sbjct: 1152 SGNERMTFLMEPDTGVLRLSNKRRQGMKLSYQLNVSVSDG---VFTNTAQVIVQVLGANL 1208 Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV-----------NAELTYTM----T 297 +P F + V EN P G +++V + + E T T+ T Sbjct: 1209 YSPVFSQRFYLAEVQENAPPGSKVIQVSLFFHSNTLIRMCPAVQPLKPLECTMTLQVRAT 1268 Query: 298 DKD--YTGNVDLPITID--------PRSGWVYTSGQLDRETQAKYQLLVT--ATDGGDPP 345 D+D G + D +G + T +LDRE +++T A DGG Sbjct: 1269 DEDSGLFGQITYSFVNDLGKTKFAVDAAGIISTLEKLDRENPLYKDMVLTVMALDGGG-- 1326 Query: 346 RSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEI 403 R++ + F +Y + + + G+ V + A+D D + R+ Y + Sbjct: 1327 RASFCSVRVILADENDNPPRFRAVEYRMSIKANVAKGSLVTQIQASDPDAGSNGRITYSL 1386 Query: 404 TGGNTRGRFSI--TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ--INI 459 + S+ G + +D Q V ATDSG + ++V I++ Sbjct: 1387 YSEARLSLVDVLEVSRFYSGWMMTKSNVDHLQGTVLSFFVKATDSGSPAKHSLVSAFIHV 1446 Query: 460 TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAH 519 + + P F Y+ ++ ED +GT + V G ++ + ++ Sbjct: 1447 VPPDAFVPSFSQPQYSFTIPEDTVVGTALGSVYMGPGQTGF-------FTAVVGEMVDSN 1499 Query: 520 HDQQFVINPQTGAITTNKLLDRETMS--GYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577 F+++ ++G I +K LD E +S + + VT R + +++ T D+E+ ++DVNDN Sbjct: 1500 QGGTFLVDRESGLIRLSKPLDYEEVSIFRFKVAVTTRRDLIEAVT-TVDLEVKILDVNDN 1558 Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY----ELDPKDREEGSFVID 633 P+F+ Y A +ME +GT V QV A D D G NG++ Y D F ID Sbjct: 1559 NPLFETNTYVATVMEGMPIGTRVVQVRALDPDWGANGQVCYVEAASSDGPITSSSVFAID 1618 Query: 634 PASGVIRTNKALDRESVATHDLKAVAID-GGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692 +G I T +D E+ +++ + VA D G SST +V I + D ND+PP FE + Sbjct: 1619 SKTGWITTVSEMDHEACSSYSFEVVASDLGELRSLSSTTVVTIAVSDCNDNPPRFERELY 1678 Query: 693 TFYISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751 + E+ +G + ++ D D N +V + I GG+ F L QG K + + Sbjct: 1679 RGAVKESDSLGEVVAVLKTSDRDGTDQNRLVSFYISGGNPRGVFGLAPVQGEWKVYVSGL 1738 Query: 752 VDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPV 810 +D + + Y L I A+ VE+ V D NDN P+ Q +++ ++ + PV Sbjct: 1739 LDREQQD---WYLLNITASDGLYVAHTAVEVTVMDANDNRPICN--QAVYSASFPEDIPV 1793 Query: 811 GP-FGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867 V A DAD + ++QY L G ++ TG + + ++ + Sbjct: 1794 NKGILTVAATDADSGSSAEIQYS-LFGIGVEDFYMDANTGELRTATIMDRETTPSYKLIA 1852 Query: 868 SVTDG 872 TDG Sbjct: 1853 QATDG 1857 Score = 262 bits (643), Expect = 7e-68 Identities = 245/867 (28%), Positives = 397/867 (45%), Gaps = 82/867 (9%) Query: 43 LTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQ----DV-FRIDGRSG 97 ++L +D K ++ EY E++T T + D+ F I+ +G Sbjct: 372 ISLMLSDYSSPKFSQKEYQAEVLTTGTHVATVTALSRSALFYDISRGNDDLCFYINHHTG 431 Query: 98 ALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTV 157 + TR LD E+ Y ++V A R+ ++ T+ V + D NDN P F + Y Sbjct: 432 VINTRKLLDFEQTPSYFLVVHALSMT-----RMEASTTVTVQVGDVNDNSPVFQQLRYVG 486 Query: 158 SVDEDISVTD-------NPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVS 210 ++ E V NP++ I+ATD D N+ + + I+ +M FSIDS +G + Sbjct: 487 TISEAAPVNSVVLGDDGNPLV--IQATDMDRNHNALLVFHILDETARMFFSIDSGTGSIR 544 Query: 211 LVKTLDYEQVRSYRLVIRAQDGGSPSRS--NTTQLLINIRDVNDNAPRFYTSLFQESVSE 268 + +LDYE + + +D G P RS + + I + ++ND+ P+ ++ + Sbjct: 545 TIASLDYEIFSEFFFQVYVRDSGQPPRSADSPADVFIKVININDSPPKLSQDTYETVLLL 604 Query: 269 NVPIGYSIVRVQAYDAD-------EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321 G +++V+A D D + V +L Y++ + NV+ ++D SG V + Sbjct: 605 PTYAGVEVLQVEASDPDMTSDFTLKSVTPQLVYSLVES----NVE-NFSVDRFSGTVTVA 659 Query: 322 G-QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380 L+++ +YQ V DG ++ A+ + +Y + E+ Sbjct: 660 NPNLNKD---RYQFTVKVWDGRF---TSMASVTVLVRKAIDSGLLYTSPEYFASIPENIS 713 Query: 381 PGTPVVTLTATDADEDNR-LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY-- 437 T VVT+ +T N L Y + N RF I G ++T P D + Y Sbjct: 714 NVT-VVTVVSTIGHRLNEPLRYTLL--NAGERFVIRPTCGV-VLTTGVPFDRELADSYEL 769 Query: 438 VLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497 V+ VS D R VQ+ + D N+ AP F N PY A+V DA + + VSA D D Sbjct: 770 VVEVSREDEILRVARVTVQVQVEDVNDNAPEFVNLPYYAAVQVDAEPESAIFKVSAVDRD 829 Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG-YLLTVTARDG 556 G+N +++YSL + N F +NP TG +T K + + + Y L + A DG Sbjct: 830 TGVNGEVSYSLKQQHRN---------FQMNPVTGELTLKKAFESDLSNAEYKLVLVATDG 880 Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616 G P LS +VE+ V VN PVF + Y + ED V TS+ + A+ + + Sbjct: 881 GFPPLS--REVELPVTVVNKAMPVFDKPFYGVTVREDVAVSTSILGINASSPEGQIVIFT 938 Query: 617 HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676 + DP + F I +G I LD E+ + L A D T +S V V + Sbjct: 939 IIDGDPSFQ----FDIGFDTGTISVIYPLDYETTQYYRLTVKATDTQTGAKSE-VDVDVV 993 Query: 677 IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG--DDSNS 734 + D+ND+ P+F++ + + EN IGTT+ ++ A D D NA+V Y I + ++ Sbjct: 994 VLDVNDNAPLFQNTSYSSVLPENVMIGTTVLKVFAQDQDSEKNAIVSYQILSDIYNSTDY 1053 Query: 735 FSLETRQGSDKAELVTMVD-LDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDN 790 F +++ G L+ M LDYE ++ + ++RA P L +DV V + VTD NDN Sbjct: 1054 FHIDSSSG-----LIFMARRLDYELVQR-HNFIVRATDSGDPTLSSDVSVTVTVTDTNDN 1107 Query: 791 APVMKDFQIIFNNY-KDCFPVGPFGR-VPAYDADVTD--KLQYRILSGNNANLILLNETT 846 P Q ++ + + P F V A DAD+ D +L+Y I+SGN L+ T Sbjct: 1108 PPNFS--QTLYEAFVSELAPRDHFVTCVQASDADICDAQRLRYSIVSGNERMTFLMEPDT 1165 Query: 847 GSMTLSPQLNTNVPKLATMEVSVTDGV 873 G + LS + + + VSV+DGV Sbjct: 1166 GVLRLSNKRRQGMKLSYQLNVSVSDGV 1192 Score = 248 bits (606), Expect = 2e-63 Identities = 246/888 (27%), Positives = 400/888 (45%), Gaps = 96/888 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D ND+ P F Y+A E + GT+VL + A D+D G N ++ YTIE + Sbjct: 267 VAVEDSNDNIPYFTSTVYDAVAYESSPFGTSVLQVTALDKDNGINGQLTYTIEAGNTGS- 325 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 VF ID +G + +LD V YT+ V+ +D P L Sbjct: 326 ------------------VFGIDAATGLIFIARALDLTSVGFYTLTVRVSDSGFP---PL 364 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +TA++ ++++ + + P+FS+K Y V +T +A + A + SA+ Y Sbjct: 365 MATASVRISLMLSDYSSPKFSQKEYQAEV-----LTTGTHVATVTAL-----SRSALFYD 414 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I GN + F I+ +G ++ K LD+EQ SY LV+ A S T + + + DV Sbjct: 415 ISRGNDDLCFYINHHTGVINTRKLLDFEQTPSYFLVVHALSMTRMEASTT--VTVQVGDV 472 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVR-------VQAYDADEGVNAELTYTMTDKDYTG 303 NDN+P F + ++SE P+ ++ +QA D D NA L + + D+ Sbjct: 473 NDNSPVFQQLRYVGTISEAAPVNSVVLGDDGNPLVIQATDMDRNHNALLVFHILDE---- 528 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA--TATXXXXXXXXXX 361 + +ID +G + T LD E +++ V D G PPRSA A Sbjct: 529 TARMFFSIDSGTGSIRTIASLDYEIFSEFFFQVYVRDSGQPPRSADSPADVFIKVININD 588 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN---------RLHYEITGGNTRGRF 412 YE L G V+ + A+D D + +L Y + N F Sbjct: 589 SPPKLSQDTYETVLLLPTYAGVEVLQVEASDPDMTSDFTLKSVTPQLVYSLVESNVE-NF 647 Query: 413 SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENA 472 S+ G +TVA P K RY TV D G + A V + + A + ++ + Sbjct: 648 SV--DRFSGTVTVANPNLNKD--RYQFTVKVWD-GRFTSMASVTVLVRKAIDSGLLYTSP 702 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 Y AS+ E+ T V VVS +N + Y+L + ++FVI P G Sbjct: 703 EYFASIPENISNVTVVTVVSTIGH--RLNEPLRYTL---------LNAGERFVIRPTCGV 751 Query: 533 I-TTNKLLDRETMSGYLLTV-TARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590 + TT DRE Y L V +R+ + ++ T V++ V DVNDN P F Y A + Sbjct: 752 VLTTGVPFDRELADSYELVVEVSREDEILRVARVT-VQVQVEDVNDNAPEFVNLPYYAAV 810 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE-S 649 DA +++ +V A D D G+NG + Y L + R +F ++P +G + KA + + S Sbjct: 811 QVDAEPESAIFKVSAVDRDTGVNGEVSYSLKQQHR---NFQMNPVTGELTLKKAFESDLS 867 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 A + L VA DGG PP S V + + + +N + PVF+ + E+ + T+I I Sbjct: 868 NAEYKLVLVATDGGFPPLSREVELPVTV--VNKAMPVFDKPFYGVTVREDVAVSTSILGI 925 Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 A P+ +V ++I GD S F + G D + + LDYE+ + Y L ++A Sbjct: 926 NASSPE---GQIVIFTIIDGDPSFQFDI----GFDTGTISVIYPLDYET-TQYYRLTVKA 977 Query: 770 ASPPLW--NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK- 826 ++V V+++V DVNDNAP+ ++ ++ +V A D D Sbjct: 978 TDTQTGAKSEVDVDVVVLDVNDNAPLFQNTSYSSVLPENVMIGTTVLKVFAQDQDSEKNA 1037 Query: 827 -LQYRILSG--NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + Y+ILS N+ + ++ ++G + ++ +L+ + + V TD Sbjct: 1038 IVSYQILSDIYNSTDYFHIDSSSGLIFMARRLDYELVQRHNFIVRATD 1085 Score = 242 bits (592), Expect = 1e-61 Identities = 199/720 (27%), Positives = 321/720 (44%), Gaps = 31/720 (4%) Query: 173 KIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQ--VRSYRLVIRAQ 230 +++ATD D G I Y+ + + +F++D+ +G +S ++ LD E + L + A Sbjct: 1264 QVRATDEDSGLFGQITYSFVNDLGKTKFAVDA-AGIISTLEKLDRENPLYKDMVLTVMAL 1322 Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290 DGG R++ + + + D NDN PRF ++ S+ NV G + ++QA D D G N Sbjct: 1323 DGGG--RASFCSVRVILADENDNPPRFRAVEYRMSIKANVAKGSLVTQIQASDPDAGSNG 1380 Query: 291 ELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350 +TY++ + VD+ SGW+ T +D V ATD G P + + Sbjct: 1381 RITYSLYSEARLSLVDVLEVSRFYSGWMMTKSNVDHLQGTVLSFFVKATDSGSPAKHSLV 1440 Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV--VTLTATDADEDNRLHYEITGGNT 408 + F QY + ED GT + V + + E+ N Sbjct: 1441 SAFIHVVPPDAFVPSFSQPQYSFTIPEDTVVGTALGSVYMGPGQTGFFTAVVGEMVDSNQ 1500 Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT---DSGGRSDTAMVQINITDANNY 465 G F + ++ GLI +++PLD+++ + V+ T D T +++ I D N+ Sbjct: 1501 GGTFLVDRES--GLIRLSKPLDYEEVSIFRFKVAVTTRRDLIEAVTTVDLEVKILDVNDN 1558 Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525 P+FE Y A+V E PIGT V+ V A D D G N Q+ Y ++ S++ F Sbjct: 1559 NPLFETNTYVATVMEGMPIGTRVVQVRALDPDWGANGQVCYVEAA--SSDGPITSSSVFA 1616 Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584 I+ +TG ITT +D E S Y V A D G + SLS TT V I+V D NDN P F+++ Sbjct: 1617 IDSKTGWITTVSEMDHEACSSYSFEVVASDLGELRSLSSTTVVTIAVSDCNDNPPRFERE 1676 Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG--VIRTN 642 LY + E +G V+ + +D D R+ G F + P G + + Sbjct: 1677 LYRGAVKESDSLGEVVAVLKTSDRDGTDQNRLVSFYISGGNPRGVFGLAPVQGEWKVYVS 1736 Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 LDRE + L A DG ++ V + + D ND+ P+ + E+ P+ Sbjct: 1737 GLLDREQQDWYLLNITASDGLYVAHTA---VEVTVMDANDNRPICNQAVYSASFPEDIPV 1793 Query: 703 GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762 I + A D D G +A + YS+ G F ++ G EL T +D E+ Sbjct: 1794 NKGILTVAATDADSGSSAEIQYSL-FGIGVEDFYMDANTG----ELRTATIMDRET-TPS 1847 Query: 763 YELVIRAA-SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDA 821 Y+L+ +A L+ + + V DVNDNAP + + Y++ P R+ A D Sbjct: 1848 YKLIAQATDGGGLFCRSDISLKVLDVNDNAPTFSSPHYLASVYENAAPKALLTRLQASDP 1907 Query: 822 D--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAM 879 D + L Y + S + L ++ +G + L L+ + V TD + A+ Sbjct: 1908 DEGLNRTLVYTLDSID--ELFSIDPVSGMVVLEKSLDRESQDSYRLRVQATDQAGQRGAL 1965 Score = 241 bits (589), Expect = 3e-61 Identities = 244/901 (27%), Positives = 389/901 (43%), Gaps = 71/901 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVL---------TLKATDQDIGKNAEVEYT 61 + VL N +SPVF + Y A V+E A G+ V+ TL + +E T Sbjct: 1201 VQVLGANLYSPVFSQRFYLAEVQENAPPGSKVIQVSLFFHSNTLIRMCPAVQPLKPLECT 1260 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDV----FRIDGRSGALLTRASLDREKVARYTVLV 117 + L T ED+ V D+ F +D +G + T LDRE Y +V Sbjct: 1261 MTLQVRAT--DEDSGLFGQITYSFVNDLGKTKFAVDA-AGIISTLEKLDRENPL-YKDMV 1316 Query: 118 KATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKAT 177 T A R +S ++ V + D+NDN P+F Y +S+ +++ ++ +I+A+ Sbjct: 1317 -LTVMALDGGGR-ASFCSVRVILADENDNPPRFRAVEYRMSIKANVA--KGSLVTQIQAS 1372 Query: 178 DADVGANSAIRYAIIGGNTQMQFSIDSLS----GDVSLVKTLDYEQVRSYRLVIRAQDGG 233 D D G+N I Y++ + +S G + +D+ Q ++A D G Sbjct: 1373 DPDAGSNGRITYSLYSEARLSLVDVLEVSRFYSGWMMTKSNVDHLQGTVLSFFVKATDSG 1432 Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293 SP++ + I++ + P F + ++ E+ +G ++ V G + Sbjct: 1433 SPAKHSLVSAFIHVVPPDAFVPSFSQPQYSFTIPEDTVVGTALGSVYMGPGQTGFFTAVV 1492 Query: 294 YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353 M D + G +D SG + S LD E + ++ V T D + T Sbjct: 1493 GEMVDSNQGGT----FLVDRESGLIRLSKPLDYEEVSIFRFKVAVTTRRDLIEAVTTVDL 1548 Query: 354 XXXXXXXXXXX-XFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRG 410 F Y + E P GT VV + A D D + ++ Y + ++ G Sbjct: 1549 EVKILDVNDNNPLFETNTYVATVMEGMPIGTRVVQVRALDPDWGANGQVCY-VEAASSDG 1607 Query: 411 RFSITS----QNGRGLITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDAN 463 + +S + G IT +D + Y V A+D G S T +V I ++D N Sbjct: 1608 PITSSSVFAIDSKTGWITTVSEMDHEACSSYSFEVVASDLGELRSLSSTTVVTIAVSDCN 1667 Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQ 522 + P FE Y +V E +G V V+ +D D N +++ +S + Sbjct: 1668 DNPPRFERELYRGAVKESDSLGEVVAVLKTSDRDGTDQNRLVSFYISG-------GNPRG 1720 Query: 523 QFVINPQTGA--ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580 F + P G + + LLDRE YLL +TA DG + T VE++V+D NDN P+ Sbjct: 1721 VFGLAPVQGEWKVYVSGLLDREQQDWYLLNITASDGLYVA---HTAVEVTVMDANDNRPI 1777 Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640 Q +Y+A+ ED V + V ATDAD G + I Y L E+ F +D +G +R Sbjct: 1778 CNQAVYSASFPEDIPVNKGILTVAATDADSGSSAEIQYSLFGIGVED--FYMDANTGELR 1835 Query: 641 TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700 T +DRE+ ++ L A A DGG S + +K+ D+ND+ P F S + EN+ Sbjct: 1836 TATIMDRETTPSYKLIAQATDGGGLFCRSDI--SLKVLDVNDNAPTFSSPHYLASVYENA 1893 Query: 701 PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760 + ++A DPDEG N + Y++ D+ FS++ G +V LD ES + Sbjct: 1894 APKALLTRLQASDPDEGLNRTLVYTLDSIDEL--FSIDPVSGM----VVLEKSLDRES-Q 1946 Query: 761 KKYELVIRAASPP-----LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR 815 Y L ++A L V + ILV DVNDNAPV + +D R Sbjct: 1947 DSYRLRVQATDQAGQRGALSTQVNLTILVLDVNDNAPVFQRRDYGVTVPEDVAVGTEVLR 2006 Query: 816 VPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGV 873 V A D+ ++ YRI SGN ++ GS+ ++ L+ V K + + DG Sbjct: 2007 VLATSVDIGLNAEISYRIRSGNELGKFNIDTNLGSIFVADDLDFEVCKDYYLTIEAWDGG 2066 Query: 874 N 874 N Sbjct: 2067 N 2067 Score = 234 bits (573), Expect = 2e-59 Identities = 231/823 (28%), Positives = 357/823 (43%), Gaps = 76/823 (9%) Query: 97 GALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT 156 G L+ LD E + Y + V+ TD + +TA + + + D NDN P FS+ Y Sbjct: 126 GTLIVAKPLDAEVQSVYNMTVQVTDGTN------FATAQVFIRVQDGNDNPPVFSQPAYD 179 Query: 157 VSVDEDISVTDNPVIAKIKATDADVGANSAIR-YAIIGGNTQMQFSIDSLSGDVSLVKTL 215 VSV EDI V + + +++A+D D A + Y + + F ++ +G V L Sbjct: 180 VSVSEDIPV--DMELVRVRASDMDERARLSYSIYGSVDPASMRLFRVNPGTGIVYTTDRL 237 Query: 216 DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275 DYE + L I +D P + ++L+ + D NDN P F ++++ E+ P G S Sbjct: 238 DYEARTQHILTIMVKDQEFPFNRDLARILVAVEDSNDNIPYFTSTVYDAVAYESSPFGTS 297 Query: 276 IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL 335 +++V A D D G+N +LTYT+ GN ID +G ++ + LD + Y L Sbjct: 298 VLQVTALDKDNGINGQLTYTIE----AGNTGSVFGIDAATGLIFIARALDLTSVGFYTLT 353 Query: 336 VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395 V +D G PP ATA+ F +Y+ E+ GT V T+TA Sbjct: 354 VRVSDSGFPPLMATASVRISLMLSDYSSPKFSQKEYQAEVL---TTGTHVATVTALSR-- 408 Query: 396 DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMV 455 + L Y+I+ GN F I G+I + LDF+Q Y L V A + V Sbjct: 409 -SALFYDISRGNDDLCFYINHHT--GVINTRKLLDFEQTPSYFLVVHALSMTRMEASTTV 465 Query: 456 QINITDANNYAPVFENAPYTASVFEDAPIGTTV-------LVVSATDSDVGINAQITYSL 508 + + D N+ +PVF+ Y ++ E AP+ + V LV+ ATD D NA + + + Sbjct: 466 TVQVGDVNDNSPVFQQLRYVGTISEAAPVNSVVLGDDGNPLVIQATDMDRNHNALLVFHI 525 Query: 509 SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP--SLSDTTD 566 E + F I+ TG+I T LD E S + V RD G P S D Sbjct: 526 LDETAR-------MFFSIDSGTGSIRTIASLDYEIFSEFFFQVYVRDSGQPPRSADSPAD 578 Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV-------GLNGRIHYE 619 V I V+++ND+ P Q Y ++ G V QV A+D D+ + ++ Y Sbjct: 579 VFIKVININDSPPKLSQDTYETVLLLPTYAGVEVLQVEASDPDMTSDFTLKSVTPQLVYS 638 Query: 620 LDPKDREEGSFVIDPASGVIR-TNKALDRESVATHDLKAVAIDGG-TPPQSSTVIVHIKI 677 L + E +F +D SG + N L+++ + DG T S TV+V I Sbjct: 639 LVESNVE--NFSVDRFSGTVTVANPNLNKD---RYQFTVKVWDGRFTSMASVTVLVRKAI 693 Query: 678 ED--INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735 + + SP F S + IS N + T + I H +E + Y++ + F Sbjct: 694 DSGLLYTSPEYFAS--IPENIS-NVTVVTVVSTI-GHRLNE----PLRYTLLNAGE--RF 743 Query: 736 SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP---LWNDVRVEILVTDVNDNAP 792 + G L T V D E YELV+ + V V++ V DVNDNAP Sbjct: 744 VIRPTCG---VVLTTGVPFDREL-ADSYELVVEVSREDEILRVARVTVQVQVEDVNDNAP 799 Query: 793 VMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMT 850 + D P +V A D D V ++ Y L + N +N TG +T Sbjct: 800 EFVNLPYYAAVQVDAEPESAIFKVSAVDRDTGVNGEVSYS-LKQQHRN-FQMNPVTGELT 857 Query: 851 LSPQLNTNVPKLATMEVSV-TD-GVNEIKAMMQLSVRLITEEM 891 L +++ V V TD G + ++L V ++ + M Sbjct: 858 LKKAFESDLSNAEYKLVLVATDGGFPPLSREVELPVTVVNKAM 900 Score = 213 bits (519), Expect = 8e-53 Identities = 196/701 (27%), Positives = 319/701 (45%), Gaps = 48/701 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V++ ND P YE + +G VL ++A+D D+ ++T++ VT + Sbjct: 581 IKVININDSPPKLSQDTYETVLLLPTYAGVEVLQVEASDPDMTS----DFTLKSVTPQLV 636 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 V++ F +D SG +T A+ + K RY VK D R Sbjct: 637 --------YSLVESNVEN-FSVDRFSGT-VTVANPNLNK-DRYQFTVKVWD------GRF 679 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +S A++ V + D+ ++ Y S+ E+IS N + + +T N +RY Sbjct: 680 TSMASVTVLVRKAIDSGLLYTSPEYFASIPENIS---NVTVVTVVSTIGH-RLNEPLRYT 735 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 ++ N +F I G V D E SY LV+ R + + + D Sbjct: 736 LL--NAGERFVIRPTCGVVLTTGVPFDRELADSYELVVEVSREDEILRVARVTVQVQVED 793 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 VNDNAP F + +V + +I +V A D D GVN E++Y++ + ++ P+ Sbjct: 794 VNDNAPEFVNLPYYAAVQVDAEPESAIFKVSAVDRDTGVNGEVSYSLKQQHRNFQMN-PV 852 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 T + + S + A+Y+L++ ATDGG PP S F Sbjct: 853 TGELTLKKAFESDL----SNAEYKLVLVATDGGFPPLSREV--ELPVTVVNKAMPVFDKP 906 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 Y V + ED T ++ + A+ + E + + I G+ +F I G I+V PL Sbjct: 907 FYGVTVREDVAVSTSILGINAS-SPEGQIVIFTIIDGDPSFQFDIGFDT--GTISVIYPL 963 Query: 430 DFKQERRYVLTVSATDS-GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 D++ + Y LTV ATD+ G V + + D N+ AP+F+N Y++ + E+ IGTTV Sbjct: 964 DYETTQYYRLTVKATDTQTGAKSEVDVDVVVLDVNDNAPLFQNTSYSSVLPENVMIGTTV 1023 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 L V A D D NA ++Y + S+I N F I+ +G I + LD E + + Sbjct: 1024 LKVFAQDQDSEKNAIVSYQILSDIYNST-----DYFHIDSSSGLIFMARRLDYELVQRHN 1078 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 V A D G P+LS V ++V D NDN P F Q LY A + E A V+ V A+DA Sbjct: 1079 FIVRATDSGDPTLSSDVSVTVTVTDTNDNPPNFSQTLYEAFVSELAPRDHFVTCVQASDA 1138 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 D+ R+ Y + E +F+++P +GV+R + + ++ L V++ G + Sbjct: 1139 DICDAQRLRYSI-VSGNERMTFLMEPDTGVLRLSNKRRQGMKLSYQLN-VSVSDGVFTNT 1196 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 + VIV ++ N PVF + EN+P G+ + ++ Sbjct: 1197 AQVIV--QVLGANLYSPVFSQRFYLAEVQENAPPGSKVIQV 1235 Score = 209 bits (510), Expect = 1e-51 Identities = 204/793 (25%), Positives = 347/793 (43%), Gaps = 57/793 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D ND+SPVF+ +Y ++ E A + VL D G ++ T D Sbjct: 467 VQVGDVNDNSPVFQQLRYVGTISEAAPVNSVVLG------DDGNPLVIQAT------DMD 514 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +A + F ID +G++ T ASLD E + + V D P Sbjct: 515 RNHNALLVFHILDETARMFFSIDSGTGSIRTIASLDYEIFSEFFFQVYVRDSGQPPRSA- 573 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTY-TVSVDEDISVTDNPVIAKIKATDADVGANSAIR- 188 S A + + +I+ ND+ P+ S+ TY TV + + + + +++A+D D+ ++ ++ Sbjct: 574 DSPADVFIKVININDSPPKLSQDTYETVLLLPTYAGVE---VLQVEASDPDMTSDFTLKS 630 Query: 189 ------YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 Y+++ N + FS+D SG V++ + + R Y+ ++ DG S ++ T Sbjct: 631 VTPQLVYSLVESNVE-NFSVDRFSGTVTVANP-NLNKDR-YQFTVKVWDGRFTSMASVTV 687 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 L +R D+ + + + S+ EN+ ++V V + +N L YT+ Sbjct: 688 L---VRKAIDSGLLYTSPEYFASIPENIS-NVTVVTVVS-TIGHRLNEPLRYTLL----- 737 Query: 303 GNVDLPITIDPRSGWVYTSG-QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 N I P G V T+G DRE Y+L+V + + R A T Sbjct: 738 -NAGERFVIRPTCGVVLTTGVPFDRELADSYELVVEVSREDEILRVARVTVQVQVEDVND 796 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421 F+ Y + D P + + ++A D D + F + G Sbjct: 797 NAPEFVNLPYYAAVQVDAEPESAIFKVSAVDRDTGVNGEVSYSLKQQHRNFQMNPVTGEL 856 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 + A D Y L + ATD G + V++ +T N PVF+ Y +V ED Sbjct: 857 TLKKAFESDLSNAE-YKLVLVATDGGFPPLSREVELPVTVVNKAMPVFDKPFYGVTVRED 915 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 + T++L ++A+ + I + +++ I + QF I TG I+ LD Sbjct: 916 VAVSTSILGINASSPEGQI---VIFTI---IDGDP----SFQFDIGFDTGTISVIYPLDY 965 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 ET Y LTV A D + S+ DV++ V+DVNDN P+F+ Y++ + E+ ++GT+V Sbjct: 966 ETTQYYRLTVKATDTQTGAKSEV-DVDVVVLDVNDNAPLFQNTSYSSVLPENVMIGTTVL 1024 Query: 602 QVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 +V A D D N + Y+ L F ID +SG+I + LD E V H+ A Sbjct: 1025 KVFAQDQDSEKNAIVSYQILSDIYNSTDYFHIDSSSGLIFMARRLDYELVQRHNFIVRAT 1084 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 D G P SS V V + + D ND+PP F ++SE +P + ++A D D Sbjct: 1085 DSGDPTLSSDVSVTVTVTDTNDNPPNFSQTLYEAFVSELAPRDHFVTCVQASDADICDAQ 1144 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRV 780 + YSI G++ +F +E G ++ + + + + Y+L + + N +V Sbjct: 1145 RLRYSIVSGNERMTFLMEPDTG-----VLRLSNKRRQGMKLSYQLNVSVSDGVFTNTAQV 1199 Query: 781 EILVTDVNDNAPV 793 + V N +PV Sbjct: 1200 IVQVLGANLYSPV 1212 Score = 204 bits (499), Expect = 2e-50 Identities = 174/550 (31%), Positives = 246/550 (44%), Gaps = 41/550 (7%) Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239 D GA G+ MQF + G + + K LD E Y + ++ DG + Sbjct: 99 DTGAQQHPHINDAAGSFDMQFDLQVGVGTLIVAKPLDAEVQSVYNMTVQVTDG---TNFA 155 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 T Q+ I ++D NDN P F + SVSE++P+ +VRV+A D DE A L+Y++ Sbjct: 156 TAQVFIRVQDGNDNPPVFSQPAYDVSVSEDIPVDMELVRVRASDMDE--RARLSYSIYGS 213 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 ++ L ++P +G VYT+ +LD E + ++ L + D P A Sbjct: 214 VDPASMRL-FRVNPGTGIVYTTDRLDYEARTQHILTIMVKDQEFPFNRDLARILVAVEDS 272 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQ 417 F Y+ E P GT V+ +TA D D + +L Y I GNT F I + Sbjct: 273 NDNIPYFTSTVYDAVAYESSPFGTSVLQVTALDKDNGINGQLTYTIEAGNTGSVFGIDA- 331 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYT 475 GLI +A+ LD Y LTV +DSG TA V+I++ ++ +P F Y Sbjct: 332 -ATGLIFIARALDLTSVGFYTLTVRVSDSGFPPLMATASVRISLMLSDYSSPKFSQKEYQ 390 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 A V GT V V+A + + Y +S + D F IN TG I T Sbjct: 391 AEVL---TTGTHVATVTALS-----RSALFYDISR-------GNDDLCFYINHHTGVINT 435 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 KLLD E Y L V A + + +T V + V DVNDN PVF+Q Y I E A Sbjct: 436 RKLLDFEQTPSYFLVVHAL--SMTRMEASTTVTVQVGDVNDNSPVFQQLRYVGTISEAAP 493 Query: 596 VGTSV-------SQVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGVIRTNKALDR 647 V + V + ATD D N + + LD R F ID +G IRT +LD Sbjct: 494 VNSVVLGDDGNPLVIQATDMDRNHNALLVFHILDETARM--FFSIDSGTGSIRTIASLDY 551 Query: 648 ESVATHDLKAVAIDGGTPPQS--STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 E + + D G PP+S S V IK+ +INDSPP D + + G Sbjct: 552 EIFSEFFFQVYVRDSGQPPRSADSPADVFIKVININDSPPKLSQDTYETVLLLPTYAGVE 611 Query: 706 IGEIRAHDPD 715 + ++ A DPD Sbjct: 612 VLQVEASDPD 621 Score = 181 bits (440), Expect = 3e-43 Identities = 142/486 (29%), Positives = 233/486 (47%), Gaps = 40/486 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 Q+ V D ND++P F Y A+V+ A + + + A D+D G N EV Y+++ + Sbjct: 788 QVQVEDVNDNAPEFVNLPYYAAVQVDAEPESAIFKVSAVDRDTGVNGEVSYSLKQQHRN- 846 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDRE-KVARYTVLVKATDQASPVSD 128 F+++ +G L + + + + A Y +++ ATD P Sbjct: 847 --------------------FQMNPVTGELTLKKAFESDLSNAEYKLVLVATDGGFPP-- 884 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 LS + V ++ N P F + Y V+V ED++V+ + I I A+ + + Sbjct: 885 -LSREVELPVTVV--NKAMPVFDKPFYGVTVREDVAVSTS--ILGINASSPE---GQIVI 936 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 + II G+ QF I +G +S++ LDYE + YRL ++A D + ++S ++ + Sbjct: 937 FTIIDGDPSFQFDIGFDTGTISVIYPLDYETTQYYRLTVKATDTQTGAKSEVDVDVV-VL 995 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 DVNDNAP F + + + ENV IG ++++V A D D NA ++Y + Y + D Sbjct: 996 DVNDNAPLFQNTSYSSVLPENVMIGTTVLKVFAQDQDSEKNAIVSYQILSDIYN-STDY- 1053 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 ID SG ++ + +LD E ++ +V ATD GDP S+ + F Sbjct: 1054 FHIDSSSGLIFMARRLDYELVQRHNFIVRATDSGDPTLSSDVSVTVTVTDTNDNPPNFSQ 1113 Query: 369 GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 YE ++E P V + A+DAD + RL Y I GN R F + G ++ ++ Sbjct: 1114 TLYEAFVSELAPRDHFVTCVQASDADICDAQRLRYSIVSGNERMTFLMEPDTG--VLRLS 1171 Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 + Y L VS +D G ++TA V + + AN Y+PVF Y A V E+AP G+ Sbjct: 1172 NKRRQGMKLSYQLNVSVSD-GVFTNTAQVIVQVLGANLYSPVFSQRFYLAEVQENAPPGS 1230 Query: 487 TVLVVS 492 V+ VS Sbjct: 1231 KVIQVS 1236 Score = 169 bits (410), Expect = 1e-39 Identities = 132/416 (31%), Positives = 196/416 (47%), Gaps = 26/416 (6%) Query: 387 TLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446 T+ A D H G+ +F + Q G G + VA+PLD + + Y +TV TD Sbjct: 94 TVEADDTGAQQHPHINDAAGSFDMQFDL--QVGVGTLIVAKPLDAEVQSVYNMTVQVTD- 150 Query: 447 GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506 G TA V I + D N+ PVF Y SV ED P+ ++ V A+D D A+++Y Sbjct: 151 GTNFATAQVFIRVQDGNDNPPVFSQPAYDVSVSEDIPVDMELVRVRASDMDE--RARLSY 208 Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566 S+ + ++ + F +NP TG + T LD E + ++LT+ +D P D Sbjct: 209 SIYGSVDPASM----RLFRVNPGTGIVYTTDRLDYEARTQHILTIMVKDQEFPFNRDLAR 264 Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE 626 + ++V D NDN P F +Y A E + GTSV QV A D D G+NG++ Y ++ + Sbjct: 265 ILVAVEDSNDNIPYFTSTVYDAVAYESSPFGTSVLQVTALDKDNGINGQLTYTIEAGN-- 322 Query: 627 EGS-FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685 GS F ID A+G+I +ALD SV + L D G PP +T V I + + S P Sbjct: 323 TGSVFGIDAATGLIFIARALDLTSVGFYTLTVRVSDSGFPPLMATASVRISLMLSDYSSP 382 Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745 F Y +E GT + + A + + Y I G+D F + G Sbjct: 383 KFSQ---KEYQAEVLTTGTHVATVTALS-----RSALFYDISRGNDDLCFYINHHTG--- 431 Query: 746 AELVTMVDLDYESPRKKYELVIRAAS-PPLWNDVRVEILVTDVNDNAPVMKDFQII 800 + T LD+E Y LV+ A S + V + V DVNDN+PV + + + Sbjct: 432 -VINTRKLLDFEQ-TPSYFLVVHALSMTRMEASTTVTVQVGDVNDNSPVFQQLRYV 485 Score = 150 bits (364), Expect = 5e-34 Identities = 124/436 (28%), Positives = 203/436 (46%), Gaps = 50/436 (11%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 ++ I VLD ND++PVF+ + Y +V E + GT VL + AT DIG NAE+ Y I + Sbjct: 1969 VNLTILVLDVNDNAPVFQRRDYGVTVPEDVAVGTEVLRVLATSVDIGLNAEISYRIR--S 2026 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 + L F ID G++ LD E Y + ++A D +P Sbjct: 2027 GNELGK-----------------FNIDTNLGSIFVADDLDFEVCKDYYLTIEAWDGGNP- 2068 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 LSS + ++++D NDN P FS+ Y V V ED SV ++ ++ A D D N Sbjct: 2069 --PLSSATVVTIDLMDVNDNAPTFSQDIYNVLVSEDASV--GQMVTRVSAEDLDSQGNGR 2124 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 I Y+I+ G+ F ID ++G + + K LD E V Y L ++A D GSP+ S+T L I+ Sbjct: 2125 ITYSILKGDRNNHFWIDPVTGILKVNKRLDRELVSRYSLSVQAFDSGSPAMSSTVTLNID 2184 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY----------DADEGVNAE-LTYT 295 I D+NDN+P F + P +V V++Y ++ + L + Sbjct: 2185 ISDINDNSPVFTPPNSTAIIQVPAP-ALLLVFVRSYISLPPPLSHLQLNQAAGSTLLKLS 2243 Query: 296 MTDKD------------YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD 343 ++DKD +GN + ++D ++G + ++ D E ++ L + +D G Sbjct: 2244 VSDKDSPKNGPPFDFRIVSGNEENFFSLD-QAGTLKSNRVFDPEAPREFTLEIQVSDSGK 2302 Query: 344 PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEI 403 P +A++ P + + +A D PG P+ + ATD D ++ L + Sbjct: 2303 PRLAASSWVFLRVIGNSQYKPLVSPLEIFIVMATDTFPGGPIGRIYATDRDPNDVLSF-T 2361 Query: 404 TGGNTRGRFSITSQNG 419 ++ F I Q+G Sbjct: 2362 QKLQSKSMFKINRQDG 2377 Score = 77.8 bits (183), Expect = 4e-12 Identities = 71/270 (26%), Positives = 121/270 (44%), Gaps = 19/270 (7%) Query: 630 FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES 689 F + G + K LD E + +++ DG +T V I+++D ND+PPVF Sbjct: 119 FDLQVGVGTLIVAKPLDAEVQSVYNMTVQVTDG---TNFATAQVFIRVQDGNDNPPVFSQ 175 Query: 690 DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV 749 +SE+ P+ + +RA D DE A + YSI G D S L R + Sbjct: 176 PAYDVSVSEDIPVDMELVRVRASDMDE--RARLSYSIYGSVDPASMRL-FRVNPGTGIVY 232 Query: 750 TMVDLDYESPRKKY-ELVIRAASPPLWNDV-RVEILVTDVNDNAPVMKDFQIIFNNYKDC 807 T LDYE+ + ++++ P D+ R+ + V D NDN P +++ Sbjct: 233 TTDRLDYEARTQHILTIMVKDQEFPFNRDLARILVAVEDSNDNIPYFTS--TVYDAV--A 288 Query: 808 FPVGPFG----RVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPK 861 + PFG +V A D D + +L Y I +GN ++ ++ TG + ++ L+ Sbjct: 289 YESSPFGTSVLQVTALDKDNGINGQLTYTIEAGNTGSVFGIDAATGLIFIARALDLTSVG 348 Query: 862 LATMEVSVTD-GVNEIKAMMQLSVRLITEE 890 T+ V V+D G + A + + L+ + Sbjct: 349 FYTLTVRVSDSGFPPLMATASVRISLMLSD 378 Score = 40.7 bits (91), Expect = 0.57 Identities = 15/43 (34%), Positives = 22/43 (51%) Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 T A C + + C PC NG +C + ++C C +G TG C Sbjct: 2887 TGARCEVELTSCMPDPCQNGGDCKPVGSAFLCSCPQGLTGLIC 2929 Score = 38.3 bits (85), Expect = 3.0 Identities = 12/39 (30%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C + + C + C NG EC + + ++ C+C +G G C Sbjct: 2929 CDQDVNECEHSECGNGGECVNTFGSFFCNCSQGSEGPFC 2967 >UniRef50_A7T100 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 2058 Score = 385 bits (947), Expect = e-104 Identities = 274/869 (31%), Positives = 429/869 (49%), Gaps = 60/869 (6%) Query: 17 NDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAX 76 ND SP+FE Y +V E AS G + + ATD+D G NA + Y+ N +A Sbjct: 1083 NDESPLFEKSMYYVNVSESASRGIVIGRVTATDRDEGINAIIFYSS--------NGAEAK 1134 Query: 77 XXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATI 136 F + +G ++ + LDRE Y + V A + + D +T + Sbjct: 1135 -------------FYVSRSTGDIIVDSPLDREFKNVYILNVTAANIVAGAQD---TTTQV 1178 Query: 137 HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNT 196 H+ + D D+ P F+ + TV + E+ S+ N + KI A D D+G I Y+I G+ Sbjct: 1179 HITVTDVIDDKPYFNSSSLTVKLSENASIGTN--VTKITALDKDIG--DTISYSIANGDP 1234 Query: 197 QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256 F+ID+++G++ V LD E V Y L ++A+D + S+ ++++ + DVNDN P Sbjct: 1235 YGLFTIDNVTGEIRTVAELDRENVTQYELFVQAKDSVN-LVSDLLKVVVQVEDVNDNPPV 1293 Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316 F + E P G SI++V+A DAD G NA + Y++ + NV +T++ +G Sbjct: 1294 FSMPGYTIEYWEESPEGTSILQVKAIDADIGDNAAVLYSIVE-----NVTDYVTVNAITG 1348 Query: 317 WV-YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375 + S QLDRE + + + ATD G P +S+TA+ F Y + Sbjct: 1349 VISLGSSQLDREVEEYFNFTIRATDSGVPSKSSTASVAIKLVDINDNSPVFNNTDYYAYV 1408 Query: 376 AEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ 433 E++P GTPV+ +TA+D D + +L Y + G RF+I G IT +PL+ ++ Sbjct: 1409 RENQPAGTPVLVVTASDKDVGTNAKLSY-VLSGVLYTRFAIDPDTGN--ITTREPLNREE 1465 Query: 434 ERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491 Y LT+ A DS R T V I +TDAN++ P F + Y SV ED +G TV V Sbjct: 1466 TGSYTLTLRAVDSAIRAREGTTRVIITVTDANDHVPQFTQSGYAFSVREDVKVGHTVGRV 1525 Query: 492 SATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTV 551 + TD D+ NA++ Y +SS N ++ F +N TG I+T LDRE + Y L + Sbjct: 1526 ATTDEDINDNARVRYYISS--GNTSL-----MFSVNETTGIISTTSTLDREQNASYTLII 1578 Query: 552 TARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG 611 TA+D G+P+L T V I++ DVNDN+P+F + +Y + E + T V QV ATD D G Sbjct: 1579 TAKDHGIPALESNTSVMITIEDVNDNKPLFSKSVYNVTLRESVFLKTQVVQVIATDPDEG 1638 Query: 612 LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671 NG+ Y++ D ++ F ID +G+I LD E + ++L A D GTPP + Sbjct: 1639 ANGQFTYKITAGDTDD-VFYIDANTGLITIKAKLDYEKTSLYNLTVSAQDLGTPPLTGAC 1697 Query: 672 IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGD 730 V I + D++D+ PVF + + EN G + + A D D E + V+Y I+ G+ Sbjct: 1698 FVEIHVSDVDDNAPVFHKPRYSAELYENVTRGHHVITVNATDIDAEASHKRVYYRIESGN 1757 Query: 731 DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND----VRVEILVTD 786 + F + + G L+ E+ +YEL + A S + V I V D Sbjct: 1758 TDSMFLIGEQSGVITLNCTPSGCLNRET-HARYELQVAAISRVNLTEQKSLVPAVITVLD 1816 Query: 787 VNDNAPVMKDFQIIFNNYKDCFPV--GPFGRVPAYDAD--VTDKLQYRILSGNNANLILL 842 VNDNAP + + +D P+ V A D D + ++ + I+SGN + + Sbjct: 1817 VNDNAPRFDSESYVRSVLEDTGPITDATILTVKAQDGDEGESGEIIFTIVSGNENGVFQM 1876 Query: 843 NETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + TG +T + L+ ++ V D Sbjct: 1877 DNKTGVLTRTRPLDREDTSFYSLVVMAED 1905 Score = 364 bits (895), Expect = 2e-98 Identities = 279/863 (32%), Positives = 406/863 (47%), Gaps = 72/863 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D D P F + E AS GT V + A D+DIG + Y+I D Sbjct: 1180 ITVTDVIDDKPYFNSSSLTVKLSENASIGTNVTKITALDKDIGDT--ISYSI--ANGDPY 1235 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +F ID +G + T A LDRE V +Y + V+A D + VSD L Sbjct: 1236 G-----------------LFTIDNVTGEIRTVAELDRENVTQYELFVQAKDSVNLVSDLL 1278 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + V + D NDN P FS YT+ E+ + I ++KA DAD+G N+A+ Y+ Sbjct: 1279 K----VVVQVEDVNDNPPVFSMPGYTIEYWEE--SPEGTSILQVKAIDADIGDNAAVLYS 1332 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I+ N ++++++G +SL + LD E + IRA D G PS+S+T + I + D Sbjct: 1333 IV-ENVTDYVTVNAITGVISLGSSQLDREVEEYFNFTIRATDSGVPSKSSTASVAIKLVD 1391 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 +NDN+P F + + V EN P G ++ V A D D G NA+L+Y ++ YT Sbjct: 1392 INDNSPVFNNTDYYAYVRENQPAGTPVLVVTASDKDVGTNAKLSYVLSGVLYT-----RF 1446 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 IDP +G + T L+RE Y L + A D R T F Sbjct: 1447 AIDPDTGNITTREPLNREETGSYTLTLRAVDSAIRAREGTTRVIITVTDANDHVPQFTQS 1506 Query: 370 QYEVELAEDEPPGTPVVTLTATDAD-EDN-RLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 Y + ED G V + TD D DN R+ Y I+ GNT FS+ G+I+ Sbjct: 1507 GYAFSVREDVKVGHTVGRVATTDEDINDNARVRYYISSGNTSLMFSVNETT--GIISTTS 1564 Query: 428 PLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 LD +Q Y L ++A D G V I I D N+ P+F + Y ++ E + Sbjct: 1565 TLDREQNASYTLIITAKDHGIPALESNTSVMITIEDVNDNKPLFSKSVYNVTLRESVFLK 1624 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 T V+ V ATD D G N Q TY +++ D F I+ TG IT LD E S Sbjct: 1625 TQVVQVIATDPDEGANGQFTYKITA-------GDTDDVFYIDANTGLITIKAKLDYEKTS 1677 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 Y LTV+A+D G P L+ VEI V DV+DN PVF + Y+A + E+ G V V A Sbjct: 1678 LYNLTVSAQDLGTPPLTGACFVEIHVSDVDDNAPVFHKPRYSAELYENVTRGHHVITVNA 1737 Query: 606 TDADV-GLNGRIHYELDPKDREEGSFVIDPASGVIRTN----KALDRESVATHDLKAVAI 660 TD D + R++Y ++ + F+I SGVI N L+RE+ A ++L+ AI Sbjct: 1738 TDIDAEASHKRVYYRIE-SGNTDSMFLIGEQSGVITLNCTPSGCLNRETHARYELQVAAI 1796 Query: 661 DG-GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS-PI-GTTIGEIRAHDPDEG 717 Q S V I + D+ND+ P F+S+ + E++ PI TI ++A D DEG Sbjct: 1797 SRVNLTEQKSLVPAVITVLDVNDNAPRFDSESYVRSVLEDTGPITDATILTVKAQDGDEG 1856 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPL 774 + + ++I G+++ F ++ + G L LD E Y LV+ A P L Sbjct: 1857 ESGEIIFTIVSGNENGVFQMDNKTG----VLTRTRPLDRED-TSFYSLVVMAEDKGEPAL 1911 Query: 775 WNDVRVEILVTDVNDNAPVMK-DFQIIFNNYKDCFPVG-------PFGRVPAYDADVTDK 826 + V V I V D+NDN P+++ ++ + F V P G V A D D + Sbjct: 1912 SSSVTVNITVLDMNDNLPILQTPMDVLIPERRTTFSVKENLDAGVPVGVVAAQDLDTKNL 1971 Query: 827 LQYRILSGNNANLILLNETTGSM 849 + Y I + +LNET+G + Sbjct: 1972 IYYYITNTEEQKYFILNETSGEL 1994 Score = 339 bits (834), Expect = 5e-91 Identities = 249/785 (31%), Positives = 387/785 (49%), Gaps = 68/785 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D ND+ PVF M Y E + GT++L +KA D DIG NA V Y+I Sbjct: 1282 VQVEDVNDNPPVFSMPGYTIEYWEESPEGTSILQVKAIDADIGDNAAVLYSI-------- 1333 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLVKATDQASPVSDR 129 V D ++ +G + L + LDRE + ++ATD P Sbjct: 1334 ------------VENVTDYVTVNAITGVISLGSSQLDREVEEYFNFTIRATDSGVPSK-- 1379 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 SSTA++ + ++D NDN P F+ Y V E+ PV+ + A+D DVG N+ + Y Sbjct: 1380 -SSTASVAIKLVDINDNSPVFNNTDYYAYVREN-QPAGTPVLV-VTASDKDVGTNAKLSY 1436 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 ++ G +F+ID +G+++ + L+ E+ SY L +RA D +R TT+++I + D Sbjct: 1437 -VLSGVLYTRFAIDPDTGNITTREPLNREETGSYTLTLRAVDSAIRAREGTTRVIITVTD 1495 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 ND+ P+F S + SV E+V +G+++ RV D D NA + Y ++ +GN L Sbjct: 1496 ANDHVPQFTQSGYAFSVREDVKVGHTVGRVATTDEDINDNARVRYYIS----SGNTSLMF 1551 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 +++ +G + T+ LDRE A Y L++TA D G P + + F Sbjct: 1552 SVNETTGIISTTSTLDREQNASYTLIITAKDHGIPALESNTSVMITIEDVNDNKPLFSKS 1611 Query: 370 QYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 Y V L E T VV + ATD DE + + Y+IT G+T F I + G LIT+ Sbjct: 1612 VYNVTLRESVFLKTQVVQVIATDPDEGANGQFTYKITAGDTDDVFYIDANTG--LITIKA 1669 Query: 428 PLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTASVFEDAPIG 485 LD+++ Y LTVSA D G T V+I+++D ++ APVF Y+A ++E+ G Sbjct: 1670 KLDYEKTSLYNLTVSAQDLGTPPLTGACFVEIHVSDVDDNAPVFHKPRYSAELYENVTRG 1729 Query: 486 TTVLVVSATDSDV-GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN----KLLD 540 V+ V+ATD D + ++ Y + S + D F+I Q+G IT N L+ Sbjct: 1730 HHVITVNATDIDAEASHKRVYYRIES-------GNTDSMFLIGEQSGVITLNCTPSGCLN 1782 Query: 541 RETMSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA--LVG 597 RET + Y L V A + I+V+DVNDN P F + Y +++ED + Sbjct: 1783 RETHARYELQVAAISRVNLTEQKSLVPAVITVLDVNDNAPRFDSESYVRSVLEDTGPITD 1842 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 ++ V A D D G +G I + + E G F +D +GV+ + LDRE + + L Sbjct: 1843 ATILTVKAQDGDEGESGEIIFTI-VSGNENGVFQMDNKTGVLTRTRPLDREDTSFYSLVV 1901 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFES--DCL------TFYISENSPIGTTIGEI 709 +A D G P SS+V V+I + D+ND+ P+ ++ D L TF + EN G +G + Sbjct: 1902 MAEDKGEPALSSSVTVNITVLDMNDNLPILQTPMDVLIPERRTTFSVKENLDAGVPVGVV 1961 Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 A D D +++Y I ++ F L G EL T + LD E Y L ++A Sbjct: 1962 AAQDLD--TKNLIYYYITNTEEQKYFILNETSG----ELRTRITLDREDSSVHY-LYVKA 2014 Query: 770 ASPPL 774 ++ L Sbjct: 2015 SNDKL 2019 Score = 326 bits (802), Expect = 4e-87 Identities = 270/880 (30%), Positives = 416/880 (47%), Gaps = 106/880 (12%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 D ND++PVF Q Y A + E A GTT+L + A D D G N++V+Y TA T P Sbjct: 38 DYNDNAPVFTEQPYMAKIAENARVGTTILKISAIDADSGTNSQVQYKFSNATA-TQTP-- 94 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134 F ++ +G L LD E Y ++V A D P +L S Sbjct: 95 --------------FFSLNSVNGELTLGGPLDFEVARSYMLVVIAEDLGVP---KLESRT 137 Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194 T+ + + D +D P+F + Y ++E+ + + ++A D DVG N+ I Y II G Sbjct: 138 TVIIEVTDISDMPPRFLQSFYLKEIEENTPI--GSTVVTVEARDGDVGINNPILYEIISG 195 Query: 195 NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNA 254 N+ F+IDS +G +++ ++D E+ +R+ ++A + P+ + T +++ + DVNDN Sbjct: 196 NSDGVFTIDSNTGVITVNGSIDAEKTDVFRITVKASEVPDPNSNTTVTVVVTVVDVNDNR 255 Query: 255 PRFYTSLFQESVSENVPIGYSIV--RVQAYDADEG-VNAELTYTMTDKDYTGNVDLPITI 311 P F S++ V E+V + +V ++Q D D+ V + Y + D I Sbjct: 256 PAFLQSVYIFDVREDVALPGRVVSDQLQVTDGDKNPVFRRVLYHLVGADSD-----KFAI 310 Query: 312 DPRSGWVYTSGQLDRETQAKY-------------------------QLLVTATDGGDPPR 346 DP SG +Y + LD E Q + +++ T TD + Sbjct: 311 DPTSGTLYINKTLDYEKQINFTFDWERGCGSGGGSGWDWTGRGEEKKVVATETDTSE-KF 369 Query: 347 SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEIT 404 SA A+ F Y + E+ PGT + +TATDAD L YE+ Sbjct: 370 SANASVTLTLINVNDNKPMFAKSSYNYTMDEEITPGTHIADITATDADLGTFGALTYELR 429 Query: 405 GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITD 461 GG FS+ + N G I+ AQ LD+ R+Y ++ D GG A V + + D Sbjct: 430 GGQA-AYFSVNADN--GTISAAQILDYDTLRQYQFSLVVKDGGGFYQEIAIATVTVTLQD 486 Query: 462 ANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521 N+ P F PYT+ + E+ P GT V V+ATD D G N ++++++S + + H Sbjct: 487 VNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNIS---AGDDGGH-- 541 Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581 F IN +G +TT + LDRET++ Y LTV+A D GV S + ++V+D NDN P Sbjct: 542 --FSIN-GSGLVTTARELDRETIATYTLTVSAYDHGVSSRHKHVQLTVNVLDENDNTPQI 598 Query: 582 KQQL-YTANIMEDALVGT-SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639 L T NI E A GT +S + A D D G NG++ Y + D F ++ A+G + Sbjct: 599 TDGLTITTNISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGGD---SRFTLNSATGRL 655 Query: 640 RTN-KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE----SDCLTF 694 + + LDRE ++DL D G+PP +++ VH+ I D+ND+ P F+ T+ Sbjct: 656 QISPTGLDRELKDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTPAFDPNPAQSLATY 715 Query: 695 YISENSPIGT---TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751 I+ + GT T+ +I A DPD N V YS+ GD+ F L+ G EL Sbjct: 716 VITVDEGPGTINKTLIDINATDPDADANGKVAYSL-SGDEHGFFRLDPVTG----ELSVR 770 Query: 752 VDLDYESPRK--------KYELVIRAA--SPPLWN----DVRVEILVTDVNDNAPVMKDF 797 +LD ESP+ ++ L I A + P+ + VRV I V D NDN+P + Sbjct: 771 KELDRESPQMSRNAQGDGRFLLDITATDQATPISDRKSATVRVSITVRDTNDNSPQFQSQ 830 Query: 798 QIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGN 835 + P +V A D D+ K+ Y I G+ Sbjct: 831 NYETRLSEAARPGSNVIQVSATDQDLEYKGKVIYNITDGD 870 Score = 309 bits (758), Expect = 9e-82 Identities = 272/916 (29%), Positives = 416/916 (45%), Gaps = 112/916 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D +D P F Y + E G+TV+T++A D D+G N + Y E+++ ++ Sbjct: 141 IEVTDISDMPPRFLQSFYLKEIEENTPIGSTVVTVEARDGDVGINNPILY--EIISGNS- 197 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 VF ID +G + S+D EK + + VKA++ P S+ Sbjct: 198 ----------------DGVFTIDSNTGVITVNGSIDAEKTDVFRITVKASEVPDPNSN-- 239 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG-ANSAIRY 189 +T T+ V ++D NDN P F + Y V ED+++ V +++ TD D + Y Sbjct: 240 -TTVTVVVTVVDVNDNRPAFLQSVYIFDVREDVALPGRVVSDQLQVTDGDKNPVFRRVLY 298 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY------------------------RL 225 ++G ++ +F+ID SG + + KTLDYE+ ++ + Sbjct: 299 HLVGADSD-KFAIDPTSGTLYINKTLDYEKQINFTFDWERGCGSGGGSGWDWTGRGEEKK 357 Query: 226 VIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD 285 V+ + S S + + + +VNDN P F S + ++ E + G I + A DAD Sbjct: 358 VVATETDTSEKFSANASVTLTLINVNDNKPMFAKSSYNYTMDEEITPGTHIADITATDAD 417 Query: 286 EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP 345 G LTY + G +++ +G + + LD +T +YQ + DGG Sbjct: 418 LGTFGALTYELR-----GGQAAYFSVNADNGTISAAQILDYDTLRQYQFSLVVKDGGGFY 472 Query: 346 RS-ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYE 402 + A AT F Y ++AE+ P GT V +TATD D E+ RL + Sbjct: 473 QEIAIATVTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFN 532 Query: 403 ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ--INIT 460 I+ G+ G FSI NG GL+T A+ LD + Y LTVSA D G S VQ +N+ Sbjct: 533 ISAGDDGGHFSI---NGSGLVTTARELDRETIATYTLTVSAYDHGVSSRHKHVQLTVNVL 589 Query: 461 DANNYAP-VFENAPYTASVFEDAPIGTTVLV-VSATDSDVGINAQITYSLSSEISNEAVA 518 D N+ P + + T ++ E A GT +L ++A D D G N Q+TYS+S Sbjct: 590 DENDNTPQITDGLTITTNISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGG------- 642 Query: 519 HHDQQFVINPQTGAITTNKL-LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577 D +F +N TG + + LDRE Y L + D G P +++T V ++++DVNDN Sbjct: 643 --DSRFTLNSATGRLQISPTGLDRELKDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDN 700 Query: 578 EPVFK----QQLYTANIMEDALVGT---SVSQVGATDADVGLNGRIHYELDPKDREEGSF 630 P F Q L T I D GT ++ + ATD D NG++ Y L E G F Sbjct: 701 TPAFDPNPAQSLATYVITVDEGPGTINKTLIDINATDPDADANGKVAYSLSGD--EHGFF 758 Query: 631 VIDPASGVIRTNKALDRESV-----ATHD----LKAVAIDGGTP---PQSSTVIVHIKIE 678 +DP +G + K LDRES A D L A D TP +S+TV V I + Sbjct: 759 RLDPVTGELSVRKELDRESPQMSRNAQGDGRFLLDITATDQATPISDRKSATVRVSITVR 818 Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738 D ND+ P F+S +SE + G+ + ++ A D D V Y+I GD++ +E Sbjct: 819 DTNDNSPQFQSQNYETRLSEAARPGSNVIQVSATDQDLEYKGKVIYNITDGDENRKCEVE 878 Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQ 798 +LV Y +K V+ S V I V DVNDN PV + Sbjct: 879 --------KLVR----HYNWHKKN--CVLCKESKCSVERTYVVIYVDDVNDNDPVFNQSK 924 Query: 799 IIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQL 855 + ++ P G P RV A D D K+ Y++ +GN + +N TG +T++ + Sbjct: 925 YAADVLENS-PTGTPVLRVHASDRDQGANGKITYKLTNGNKDDAFSINNVTGEITVAGVI 983 Query: 856 NTNVPKLATMEVSVTD 871 + + V D Sbjct: 984 DREAVHTFVLTVQAED 999 Score = 304 bits (746), Expect = 2e-80 Identities = 246/831 (29%), Positives = 402/831 (48%), Gaps = 96/831 (11%) Query: 140 IIDD-NDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN-TQ 197 I+DD NDN P F+E+ Y + E+ V I KI A DAD G NS ++Y TQ Sbjct: 35 IVDDYNDNAPVFTEQPYMAKIAENARV--GTTILKISAIDADSGTNSQVQYKFSNATATQ 92 Query: 198 MQF-SIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256 F S++S++G+++L LD+E RSY LV+ A+D G P + T ++I + D++D PR Sbjct: 93 TPFFSLNSVNGELTLGGPLDFEVARSYMLVVIAEDLGVPKLESRTTVIIEVTDISDMPPR 152 Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316 F S + + + EN PIG ++V V+A D D G+N + Y + +GN D TID +G Sbjct: 153 FLQSFYLKEIEENTPIGSTVVTVEARDGDVGINNPILYEII----SGNSDGVFTIDSNTG 208 Query: 317 WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376 + +G +D E +++ V A++ DP + T T F+ Y ++ Sbjct: 209 VITVNGSIDAEKTDVFRITVKASEVPDPNSNTTVTVVVTVVDVNDNRPAFLQSVYIFDVR 268 Query: 377 EDEP-PGTPVVT-LTATDADED---NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431 ED PG V L TD D++ R+ Y + G ++ +F+I +G + + + LD+ Sbjct: 269 EDVALPGRVVSDQLQVTDGDKNPVFRRVLYHLVGADS-DKFAIDPTSGT--LYINKTLDY 325 Query: 432 KQERRYV-------------------------LTVSATDSGGR-SDTAMVQINITDANNY 465 +++ + + + TD+ + S A V + + + N+ Sbjct: 326 EKQINFTFDWERGCGSGGGSGWDWTGRGEEKKVVATETDTSEKFSANASVTLTLINVNDN 385 Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525 P+F + Y ++ E+ GT + ++ATD+D+G +TY E+ A+ F Sbjct: 386 KPMFAKSSYNYTMDEEITPGTHIADITATDADLGTFGALTY----ELRGGQAAY----FS 437 Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGG--VPSLSDTTDVEISVVDVNDNEPVFKQ 583 +N G I+ ++LD +T+ Y ++ +DGG ++ T V +++ DVNDN+P F Sbjct: 438 VNADNGTISAAQILDYDTLRQYQFSLVVKDGGGFYQEIAIAT-VTVTLQDVNDNDPEFTG 496 Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK 643 YT++I E+ GT V QV ATD D G NGR+ + + D + G F I+ SG++ T + Sbjct: 497 MPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISAGD-DGGHFSIN-GSGLVTTAR 554 Query: 644 ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP-VFESDCLTFYISENSPI 702 LDRE++AT+ L A D G + V + + + D ND+ P + + +T ISE + Sbjct: 555 ELDRETIATYTLTVSAYDHGVSSRHKHVQLTVNVLDENDNTPQITDGLTITTNISEGAGG 614 Query: 703 GTTI-GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761 GT + I A DPD G N + YS+ GGD + F+L + G + ++ LD E + Sbjct: 615 GTVLLSSIAAVDPDAGSNGQLTYSMSGGD--SRFTLNSATGRLQ---ISPTGLDREL-KD 668 Query: 762 KYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQI-IFNNYKDCFPVGPFGRVP 817 Y+L+I SPP N V + + DVNDN P Y GP G + Sbjct: 669 SYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTPAFDPNPAQSLATYVITVDEGP-GTIN 727 Query: 818 AY---------DADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLA----- 863 DAD K+ Y LSG+ L+ TG +++ +L+ P+++ Sbjct: 728 KTLIDINATDPDADANGKVAYS-LSGDEHGFFRLDPVTGELSVRKELDRESPQMSRNAQG 786 Query: 864 ----TMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLS 910 ++++ TD I +VR+ SITVR + + QF S Sbjct: 787 DGRFLLDITATDQATPISDRKSATVRV--------SITVRDTNDNSPQFQS 829 Score = 273 bits (670), Expect = 4e-71 Identities = 198/629 (31%), Positives = 291/629 (46%), Gaps = 30/629 (4%) Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 +ND +P F S++ +VSE+ G I RV A D DEG+NA + Y+ + + Sbjct: 1082 INDESPLFEKSMYYVNVSESASRGIVIGRVTATDRDEGINAIIFYS------SNGAEAKF 1135 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 + +G + LDRE + Y L VTA + + T F Sbjct: 1136 YVSRSTGDIIVDSPLDREFKNVYILNVTAANIVAGAQDTTTQVHITVTDVIDDKPYFNSS 1195 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 V+L+E+ GT V +TA D D + + Y I G+ G F+I + G + TVA+ L Sbjct: 1196 SLTVKLSENASIGTNVTKITALDKDIGDTISYSIANGDPYGLFTIDNVTGE-IRTVAE-L 1253 Query: 430 DFKQERRYVLTVSATDSGGR-SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 D + +Y L V A DS SD V + + D N+ PVF YT +E++P GT++ Sbjct: 1254 DRENVTQYELFVQAKDSVNLVSDLLKVVVQVEDVNDNPPVFSMPGYTIEYWEESPEGTSI 1313 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT-NKLLDRETMSGY 547 L V A D+D+G NA + YS+ +++ +N TG I+ + LDRE + Sbjct: 1314 LQVKAIDADIGDNAAVLYSIVENVTD--------YVTVNAITGVISLGSSQLDREVEEYF 1365 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 T+ A D GVPS S T V I +VD+NDN PVF Y A + E+ GT V V A+D Sbjct: 1366 NFTIRATDSGVPSKSSTASVAIKLVDINDNSPVFNNTDYYAYVRENQPAGTPVLVVTASD 1425 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 DVG N ++ Y L F IDP +G I T + L+RE ++ L A+D + Sbjct: 1426 KDVGTNAKLSYVLSGVLYTR--FAIDPDTGNITTREPLNREETGSYTLTLRAVDSAIRAR 1483 Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 T V I + D ND P F F + E+ +G T+G + D D NA V Y I Sbjct: 1484 EGTTRVIITVTDANDHVPQFTQSGYAFSVREDVKVGHTVGRVATTDEDINDNARVRYYIS 1543 Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILV 784 G+ S FS+ G + T LD E Y L+I A P L ++ V I + Sbjct: 1544 SGNTSLMFSVNETTGI----ISTTSTLDREQ-NASYTLIITAKDHGIPALESNTSVMITI 1598 Query: 785 TDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILL 842 DVNDN P+ + F +V A D D + Y+I +G+ ++ + Sbjct: 1599 EDVNDNKPLFSKSVYNVTLRESVFLKTQVVQVIATDPDEGANGQFTYKITAGDTDDVFYI 1658 Query: 843 NETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + TG +T+ +L+ L + VS D Sbjct: 1659 DANTGLITIKAKLDYEKTSLYNLTVSAQD 1687 Score = 264 bits (647), Expect = 2e-68 Identities = 238/821 (28%), Positives = 377/821 (45%), Gaps = 81/821 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT--LKATDQDIGKNAEVEYTI-ELVTA 67 + V+D ND+ P F Y VRE + V++ L+ TD D KN + LV A Sbjct: 246 VTVVDVNDNRPAFLQSVYIFDVREDVALPGRVVSDQLQVTDGD--KNPVFRRVLYHLVGA 303 Query: 68 DT----LNPEDAXXXXXXXXXXVQDV-FRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122 D+ ++P + + F D G S V AT+ Sbjct: 304 DSDKFAIDPTSGTLYINKTLDYEKQINFTFDWERGCGSGGGSGWDWTGRGEEKKVVATE- 362 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 + S++ S+ A++ + +I+ NDN P F++ +Y ++DE+I T IA I ATDAD+G Sbjct: 363 -TDTSEKFSANASVTLTLINVNDNKPMFAKSSYNYTMDEEI--TPGTHIADITATDADLG 419 Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT-T 241 A+ Y + GG FS+++ +G +S + LDY+ +R Y+ + +DGG + Sbjct: 420 TFGALTYELRGGQAAY-FSVNADNGTISAAQILDYDTLRQYQFSLVVKDGGGFYQEIAIA 478 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 + + ++DVNDN P F + ++EN+P G + +V A D D G N L++ ++ D Sbjct: 479 TVTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISAGDD 538 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 G+ + SG V T+ +LDRET A Y L V+A D G R Sbjct: 539 GGHFSIN-----GSGLVTTARELDRETIATYTLTVSAYDHGVSSRHKHVQLTVNVLDEND 593 Query: 362 XXXXFMPG-QYEVELAEDEPPGTPVVTLTAT---DADEDNRLHYEITGGNTRGRFSITSQ 417 G ++E GT +++ A DA + +L Y ++GG++R F++ S Sbjct: 594 NTPQITDGLTITTNISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGGDSR--FTLNSA 651 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT--AMVQINITDANNYAPVFENAP-- 473 GR I+ LD + + Y L ++ TD+G +T V + I D N+ P F+ P Sbjct: 652 TGRLQISPTG-LDRELKDSYDLIINVTDNGSPPNTNSTTVHVTILDVNDNTPAFDPNPAQ 710 Query: 474 ----YTASVFED-APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528 Y +V E I T++ ++ATD D N ++ YSLS + H F ++P Sbjct: 711 SLATYVITVDEGPGTINKTLIDINATDPDADANGKVAYSLSGD-------EHGF-FRLDP 762 Query: 529 QTGAITTNKLLDRET--MSG-------YLLTVTARDGGVPSLSD----TTDVEISVVDVN 575 TG ++ K LDRE+ MS +LL +TA D P +SD T V I+V D N Sbjct: 763 VTGELSVRKELDRESPQMSRNAQGDGRFLLDITATDQATP-ISDRKSATVRVSITVRDTN 821 Query: 576 DNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA 635 DN P F+ Q Y + E A G++V QV ATD D+ G++ Y + D V Sbjct: 822 DNSPQFQSQNYETRLSEAARPGSNVIQVSATDQDLEYKGKVIYNITDGDENRKCEV---- 877 Query: 636 SGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695 ++R + V + K T +V I ++D+ND+ PVF Sbjct: 878 EKLVRHYNWHKKNCVLCKESKCSV--------ERTYVV-IYVDDVNDNDPVFNQSKYAAD 928 Query: 696 ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755 + ENSP GT + + A D D+G N + Y + G+ ++FS+ G E+ +D Sbjct: 929 VLENSPTGTPVLRVHASDRDQGANGKITYKLTNGNKDDAFSINNVTG----EITVAGVID 984 Query: 756 YESPRKKYELVIRA--ASPPLWNDVRVEILVT--DVNDNAP 792 E+ + L ++A P E+++T D NDN P Sbjct: 985 REAVH-TFVLTVQAEDQGEPSSRKTFAEVVITVKDENDNFP 1024 Score = 235 bits (575), Expect = 1e-59 Identities = 188/613 (30%), Positives = 295/613 (48%), Gaps = 66/613 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND+ P F Y + + E +GT V + ATD+D G+N + + I Sbjct: 482 VTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNISA------ 535 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +D F I+G SG + T LDRE +A YT+ V A D VS R Sbjct: 536 -GDDGGH------------FSING-SGLVTTARELDRETIATYTLTVSAYDHG--VSSR- 578 Query: 131 SSTATIHVNIIDDNDNYPQFSEK-TYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + VN++D+NDN PQ ++ T T ++ E +++ I A D D G+N + Y Sbjct: 579 HKHVQLTVNVLDENDNTPQITDGLTITTNISEGAG-GGTVLLSSIAAVDPDAGSNGQLTY 637 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 ++ GG+++ F+++S +G + + T LD E SY L+I D GSP +N+T + + I Sbjct: 638 SMSGGDSR--FTLNSATGRLQISPTGLDRELKDSYDLIINVTDNGSPPNTNSTTVHVTIL 695 Query: 249 DVNDNAPRFYTSLFQE------SVSENV-PIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 DVNDN P F + Q +V E I +++ + A D D N ++ Y+++ ++ Sbjct: 696 DVNDNTPAFDPNPAQSLATYVITVDEGPGTINKTLIDINATDPDADANGKVAYSLSGDEH 755 Query: 302 TGNVDL-PIT--IDPRSGWVYTSGQLDRETQA--KYQLLVTATDGGDP---PRSATATXX 353 G L P+T + R S Q+ R Q ++ L +TATD P +SAT Sbjct: 756 -GFFRLDPVTGELSVRKELDRESPQMSRNAQGDGRFLLDITATDQATPISDRKSATVRVS 814 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGR 411 F YE L+E PG+ V+ ++ATD D + ++ Y IT G+ + Sbjct: 815 ITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQVSATDQDLEYKGKVIYNITDGDENRK 874 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN 471 + + + ++ ++ V +S + V I + D N+ PVF Sbjct: 875 CEVEK--------LVRHYNWHKKN----CVLCKESKCSVERTYVVIYVDDVNDNDPVFNQ 922 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 + Y A V E++P GT VL V A+D D G N +ITY L++ + D F IN TG Sbjct: 923 SKYAADVLENSPTGTPVLRVHASDRDQGANGKITYKLTN-------GNKDDAFSINNVTG 975 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDT-TDVEISVVDVNDNEPVFKQQLYTANI 590 IT ++DRE + ++LTV A D G PS T +V I+V D NDN P F Y I Sbjct: 976 EITVAGVIDREAVHTFVLTVQAEDQGEPSSRKTFAEVVITVKDENDNFPQFSFTGYEGEI 1035 Query: 591 MEDALVGTSVSQV 603 E++ VG++++ V Sbjct: 1036 AENSPVGSTITMV 1048 Score = 222 bits (542), Expect = 1e-55 Identities = 188/691 (27%), Positives = 311/691 (45%), Gaps = 61/691 (8%) Query: 222 SYRLVIRAQD---GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR 278 +Y + +D GG +R + + + D NDNAP F + ++EN +G +I++ Sbjct: 8 NYEFTVYVEDDFNGGGLARRGSKFFFLIVDDYNDNAPVFTEQPYMAKIAENARVGTTILK 67 Query: 279 VQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA 338 + A DAD G N+++ Y ++ T +++ +G + G LD E Y L+V A Sbjct: 68 ISAIDADSGTNSQVQYKFSNA--TATQTPFFSLNSVNGELTLGGPLDFEVARSYMLVVIA 125 Query: 339 TDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--D 396 D G P + T F+ Y E+ E+ P G+ VVT+ A D D + Sbjct: 126 EDLGVPKLESRTTVIIEVTDISDMPPRFLQSFYLKEIEENTPIGSTVVTVEARDGDVGIN 185 Query: 397 NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD--SGGRSDTAM 454 N + YEI GN+ G F+I S G+ITV +D ++ + +TV A++ + T Sbjct: 186 NPILYEIISGNSDGVFTIDSNT--GVITVNGSIDAEKTDVFRITVKASEVPDPNSNTTVT 243 Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVL--VVSATDSDVG-INAQITYSLSSE 511 V + + D N+ P F + Y V ED + V+ + TD D + ++ Y L Sbjct: 244 VVVTVVDVNDNRPAFLQSVYIFDVREDVALPGRVVSDQLQVTDGDKNPVFRRVLYHL--- 300 Query: 512 ISNEAVAHHDQQFVINPQTGAITTNKLLDRETM----------------SGYLLTVTARD 555 V +F I+P +G + NK LD E SG+ T + Sbjct: 301 -----VGADSDKFAIDPTSGTLYINKTLDYEKQINFTFDWERGCGSGGGSGWDWTGRGEE 355 Query: 556 GGVPSL-SDTTD-------VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 V + +DT++ V +++++VNDN+P+F + Y + E+ GT ++ + ATD Sbjct: 356 KKVVATETDTSEKFSANASVTLTLINVNDNKPMFAKSSYNYTMDEEITPGTHIADITATD 415 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 AD+G G + YEL + + F ++ +G I + LD +++ + V DGG Q Sbjct: 416 ADLGTFGALTYEL--RGGQAAYFSVNADNGTISAAQILDYDTLRQYQFSLVVKDGGGFYQ 473 Query: 668 SSTV-IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 + V + ++D+ND+ P F T I+EN P GT + ++ A D D G N + ++I Sbjct: 474 EIAIATVTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRLSFNI 533 Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL---WNDVRVEIL 783 GDD FS+ GS + T +LD E+ Y L + A + V++ + Sbjct: 534 SAGDDGGHFSI---NGS--GLVTTARELDRET-IATYTLTVSAYDHGVSSRHKHVQLTVN 587 Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFPVGP--FGRVPAYDADVTDKLQYRILSGNNANLIL 841 V D NDN P + D I N + G + A D D Q + Sbjct: 588 VLDENDNTPQITDGLTITTNISEGAGGGTVLLSSIAAVDPDAGSNGQLTYSMSGGDSRFT 647 Query: 842 LNETTGSMTLSPQ-LNTNVPKLATMEVSVTD 871 LN TG + +SP L+ + + ++VTD Sbjct: 648 LNSATGRLQISPTGLDRELKDSYDLIINVTD 678 Score = 175 bits (425), Expect = 2e-41 Identities = 146/426 (34%), Positives = 206/426 (48%), Gaps = 26/426 (6%) Query: 452 TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE 511 TA + IT N+ +P+FE + Y +V E A G + V+ATD D GINA I YS Sbjct: 1072 TAREKRPITLINDESPLFEKSMYYVNVSESASRGIVIGRVTATDRDEGINAIIFYS---- 1127 Query: 512 ISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571 SN A A +F ++ TG I + LDRE + Y+L VTA + + TT V I+V Sbjct: 1128 -SNGAEA----KFYVSRSTGDIIVDSPLDREFKNVYILNVTAANIVAGAQDTTTQVHITV 1182 Query: 572 VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631 DV D++P F T + E+A +GT+V+++ A D D+G I Y + D G F Sbjct: 1183 TDVIDDKPYFNSSSLTVKLSENASIGTNVTKITALDKDIG--DTISYSIANGD-PYGLFT 1239 Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691 ID +G IRT LDRE+V ++L A D S + V +++ED+ND+PPVF Sbjct: 1240 IDNVTGEIRTVAELDRENVTQYELFVQAKD-SVNLVSDLLKVVVQVEDVNDNPPVFSMPG 1298 Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751 T E SP GT+I +++A D D G NA V YSI N T + Sbjct: 1299 YTIEYWEESPEGTSILQVKAIDADIGDNAAVLYSIV----ENVTDYVTVNAITGVISLGS 1354 Query: 752 VDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCF 808 LD E + + IRA P + V I + D+NDN+PV + + ++ Sbjct: 1355 SQLDRE-VEEYFNFTIRATDSGVPSKSSTASVAIKLVDINDNSPVFNNTD-YYAYVRENQ 1412 Query: 809 PVG-PFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATM 865 P G P V A D DV KL Y +LSG ++ TG++T LN T+ Sbjct: 1413 PAGTPVLVVTASDKDVGTNAKLSY-VLSGVLYTRFAIDPDTGNITTREPLNREETGSYTL 1471 Query: 866 EVSVTD 871 + D Sbjct: 1472 TLRAVD 1477 Score = 136 bits (329), Expect = 8e-30 Identities = 101/320 (31%), Positives = 160/320 (50%), Gaps = 17/320 (5%) Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633 +ND P+F++ +Y N+ E A G + +V ATD D G+N I Y + E F + Sbjct: 1082 INDESPLFEKSMYYVNVSESASRGIVIGRVTATDRDEGINAIIFYS---SNGAEAKFYVS 1138 Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693 ++G I + LDRE + L A + Q +T VHI + D+ D P F S LT Sbjct: 1139 RSTGDIIVDSPLDREFKNVYILNVTAANIVAGAQDTTTQVHITVTDVIDDKPYFNSSSLT 1198 Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753 +SEN+ IGT + +I A D D G + YSI GD F+++ G E+ T+ + Sbjct: 1199 VKLSENASIGTNVTKITALDKDIGD--TISYSIANGDPYGLFTIDNVTG----EIRTVAE 1252 Query: 754 LDYESPRKKYELVIRAA-SPPLWND-VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811 LD E+ +YEL ++A S L +D ++V + V DVNDN PV +++ Sbjct: 1253 LDRENV-TQYELFVQAKDSVNLVSDLLKVVVQVEDVNDNPPVFSMPGYTIEYWEESPEGT 1311 Query: 812 PFGRVPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTL-SPQLNTNVPKLATMEVS 868 +V A DAD+ D + Y I+ N + + +N TG ++L S QL+ V + + Sbjct: 1312 SILQVKAIDADIGDNAAVLYSIVE-NVTDYVTVNAITGVISLGSSQLDREVEEYFNFTIR 1370 Query: 869 VTD-GVNEIKAMMQLSVRLI 887 TD GV + ++++L+ Sbjct: 1371 ATDSGVPSKSSTASVAIKLV 1390 Score = 120 bits (289), Expect = 6e-25 Identities = 100/344 (29%), Positives = 163/344 (47%), Gaps = 40/344 (11%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDI-GKNAEVEYTIELVTAD 68 +I+V D +D++PVF +Y A + E + G V+T+ ATD D + V Y IE D Sbjct: 1700 EIHVSDVDDNAPVFHKPRYSAELYENVTRGHHVITVNATDIDAEASHKRVYYRIESGNTD 1759 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS----LDREKVARYTVLVKATDQAS 124 ++ F I +SG + + L+RE ARY + V A + + Sbjct: 1760 SM-------------------FLIGEQSGVITLNCTPSGCLNRETHARYELQVAAISRVN 1800 Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184 ++++ S + + ++D NDN P+F ++Y SV ED + I +KA D D G + Sbjct: 1801 -LTEQKSLVPAV-ITVLDVNDNAPRFDSESYVRSVLEDTGPITDATILTVKAQDGDEGES 1858 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 I + I+ GN F +D+ +G ++ + LD E Y LV+ A+D G P+ S++ + Sbjct: 1859 GEIIFTIVSGNENGVFQMDNKTGVLTRTRPLDREDTSFYSLVVMAEDKGEPALSSSVTVN 1918 Query: 245 INIRDVNDNAPRFYTS---LFQE-----SVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 I + D+NDN P T L E SV EN+ G + V A D D + Y + Sbjct: 1919 ITVLDMNDNLPILQTPMDVLIPERRTTFSVKENLDAGVPVGVVAAQDLD--TKNLIYYYI 1976 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD 340 T+ + ++ SG + T LDRE + + L V A++ Sbjct: 1977 TNTE----EQKYFILNETSGELRTRITLDREDSSVHYLYVKASN 2016 Score = 99 bits (238), Expect = 9e-19 Identities = 59/145 (40%), Positives = 85/145 (58%), Gaps = 2/145 (1%) Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP 622 + T V I V DVNDN+PVF Q Y A+++E++ GT V +V A+D D G NG+I Y+L Sbjct: 902 ERTYVVIYVDDVNDNDPVFNQSKYAADVLENSPTGTPVLRVHASDRDQGANGKITYKLTN 961 Query: 623 KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI-VHIKIEDIN 681 ++++ +F I+ +G I +DRE+V T L A D G P T V I ++D N Sbjct: 962 GNKDD-AFSINNVTGEITVAGVIDREAVHTFVLTVQAEDQGEPSSRKTFAEVVITVKDEN 1020 Query: 682 DSPPVFESDCLTFYISENSPIGTTI 706 D+ P F I+ENSP+G+TI Sbjct: 1021 DNFPQFSFTGYEGEIAENSPVGSTI 1045 Score = 50.0 bits (114), Expect = 0.001 Identities = 23/56 (41%), Positives = 32/56 (57%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 + I V D ND+SP F+ Q YE + E A G+ V+ + ATDQD+ +V Y I Sbjct: 811 VRVSITVRDTNDNSPQFQSQNYETRLSEAARPGSNVIQVSATDQDLEYKGKVIYNI 866 >UniRef50_A7S751 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 2676 Score = 385 bits (947), Expect = e-104 Identities = 284/886 (32%), Positives = 427/886 (48%), Gaps = 70/886 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +N+ D ND+ P F Y AS+ E + SG+ V+ L A D DIG+N+ + Y+I L Sbjct: 486 VNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSI-------L 538 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P F +D R G + +LD E + YT V ATD Sbjct: 539 TPNTP--------------FFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGGR----- 579 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S AT+HV++ D NDN P F +Y+V E+ + + I ++KA D D + R+ Sbjct: 580 SCNATVHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQS--ICQLKAIDRDSPKFAITRFI 637 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I GN FS+D SG ++L K LD E +Y L ++A DGG N + I + DV Sbjct: 638 IEQGNADEVFSVDG-SGLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDV 696 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 ND P F + + ++ E+ I V A D+G NAE+ Y+++ GN D + Sbjct: 697 NDEPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSISK----GNTDNIVL 752 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I+ +G +Y ++D E L V A D G PP A F Sbjct: 753 INS-TGTLYLQSEVDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSSS 811 Query: 371 YEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 V L ED P G T++ DAD R+ + + N F++ S G +++ + Sbjct: 812 ILVRLPEDTPIGHTFYTVSVFDADSGVLGRVSFSLLS-NPGTLFNLDSNTGA--LSLTKL 868 Query: 429 LDF-KQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 +D+ R Y L V A D G RS TAM+++ + D N+Y+PVF N YTA V E P Sbjct: 869 IDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLETTPPD 928 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 + ++ V ATD D G N +I+Y+ S++ +F + G I LDRE + Sbjct: 929 SNIIEVVATDVDSGENGRISYAFDSKVDTS-------KFGLR-NGGKIFIKSKLDREDIE 980 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 Y L V A D G P S + DV++ V DVNDN P F+Q Y + E+ V T + V A Sbjct: 981 EYNLKVIAIDHGTPRRSSSADVKVIVDDVNDNNPHFQQASYAFFVKENEPVATYLGAVSA 1040 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 +D+D G NG + Y D + F++D +G I T++ LDRE+ A++ VA DGG+ Sbjct: 1041 SDSDEGSNGHVTYRFDT---QVAQFIVDKQTGKITTSQVLDREAKASYVFSIVATDGGSS 1097 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE-GPNAVVHY 724 P+ V + + D+ND P F + + ++E+ P+G+++ + A D D+ GPN+ + Y Sbjct: 1098 PRVDKTQVTVIVRDVNDCSPKFSKNKYSVTVNEDLPVGSSLLTLIATDDDQQGPNSDITY 1157 Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVI---RAASPPLWNDVRV 780 I G +FSL G ++T+V LD E + V+ + + L + Sbjct: 1158 MIVAGP--KAFSLNQVTG-----VLTLVSPLDREVTHRHILHVVASDKGGNQSLETITYI 1210 Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTD--KLQYRILSGNNA 837 EI V DVNDN PV + + F + P+G V A D+D D K++Y+I++GN Sbjct: 1211 EINVLDVNDNYPVFIN-ETTFKTVPEKLPIGSVVAAVLAVDSDQGDNGKVRYKIVNGNTD 1269 Query: 838 NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQL 882 +NETTG ++ L+ V + VS TD G + K QL Sbjct: 1270 GTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQL 1315 Score = 363 bits (892), Expect = 5e-98 Identities = 281/874 (32%), Positives = 419/874 (47%), Gaps = 64/874 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +INV D ND +P F+ YE V E A+ T V + A DQD G N+E+ YTI A+T Sbjct: 376 RINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTI----ANT 431 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 F ID SG + T LDRE++ + + V D+ SP Sbjct: 432 TESRSYLHW-----------FAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPP--- 477 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LS ++ VN+ D NDN P F++ +Y S+ E+ S + +PV+ ++ A D D+G NS I Y Sbjct: 478 LSDNCSVIVNLTDSNDNDPYFNQSSYNASLFEN-SPSGSPVV-QLLAQDPDIGENSLILY 535 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 +I+ NT F +D G V+ +TLD+E SY + A DGG S + T +++ D Sbjct: 536 SILTPNTP--FFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGGRSCNATVH--VSLTD 591 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 +NDN P F S + EN IG SI +++A D D A + + GN D Sbjct: 592 LNDNQPVFDPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQ----GNADEVF 647 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 ++D SG + + LDRETQ Y L V A DGG A F Sbjct: 648 SVDG-SGLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKA 706 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNGRGLITVAQ 427 +Y + E + + + A D+ Y I+ GNT +I N G + + Sbjct: 707 EYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSISKGNTD---NIVLINSTGTLYLQS 763 Query: 428 PLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 +D ++ LTV A D G A V I + D N+ +P F ++ + ED PIG Sbjct: 764 EVDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSSSILVRLPEDTPIG 823 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR-ETM 544 T VS D+D G+ ++++SL +SN F ++ TGA++ KL+D + Sbjct: 824 HTFYTVSVFDADSGVLGRVSFSL---LSNPGTL-----FNLDSNTGALSLTKLIDYGNSA 875 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 Y L V A+DGG P S T +E+ VVDVND PVF YTA+++E +++ +V Sbjct: 876 RSYTLPVQAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLETTPPDSNIIEVV 935 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 ATD D G NGRI Y D K + F + + +K LDRE + ++LK +AID GT Sbjct: 936 ATDVDSGENGRISYAFDSKV-DTSKFGLRNGGKIFIKSK-LDREDIEEYNLKVIAIDHGT 993 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 P +SS+ V + ++D+ND+ P F+ F++ EN P+ T +G + A D DEG N H Sbjct: 994 PRRSSSADVKVIVDDVNDNNPHFQQASYAFFVKENEPVATYLGAVSASDSDEGSNG--HV 1051 Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVE 781 + + F ++ + G ++ T LD E+ + Y I A S P + +V Sbjct: 1052 TYRFDTQVAQFIVDKQTG----KITTSQVLDREA-KASYVFSIVATDGGSSPRVDKTQVT 1106 Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD---VTDKLQYRILSGNNA 837 ++V DVND +P + +D PVG + A D D + Y I++G A Sbjct: 1107 VIVRDVNDCSPKFSKNKYSVTVNED-LPVGSSLLTLIATDDDQQGPNSDITYMIVAGPKA 1165 Query: 838 NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 LN+ TG +TL L+ V + V +D Sbjct: 1166 --FSLNQVTGVLTLVSPLDREVTHRHILHVVASD 1197 Score = 359 bits (883), Expect = 6e-97 Identities = 252/821 (30%), Positives = 395/821 (48%), Gaps = 49/821 (5%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+ P F Y ++ E GT++L + A+D+DIG NAE++Y+IE + Sbjct: 160 ITVEDTNDNKPEFSNVSYSGTIPENIDVGTSILQVSASDKDIGTNAEIQYSIETHS---- 215 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +P Q +F I +G ++ LD E Y ++VKA D+ S S +L Sbjct: 216 DP--------------QAIFGIHPTTGVIVNNVRLDYEAKRSYLIVVKAEDKGS--SHQL 259 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI--SVTDNPVIAKIKATDADVGANSAIR 188 SS+A + + ++D NDN P +YT+ + + T +A++ +DAD G N + Sbjct: 260 SSSAIVRIEVLDVNDNNPVI-HVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVN 318 Query: 189 YAIIGGNTQMQFSIDSLSGD--VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 + GG+ D L+ + +++ ++LD E + L D G P R+ IN Sbjct: 319 VTLEGGDGYFSMKFDVLNDESIIAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRIN 378 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + DVND AP+F ++ V EN + + V A D D G N+EL YT+ + + + Sbjct: 379 VGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYL 438 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 IDP SG + T+ LDRE + L V D G PP S + F Sbjct: 439 HWFAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYF 498 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLIT 424 Y L E+ P G+PVV L A D D E++ + Y I NT F + + +GL+T Sbjct: 499 NQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSILTPNT--PFFLDPR--KGLVT 554 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 ++ LD + + Y V+ATD GGRS A V +++TD N+ PVF+ + Y+ FE+ I Sbjct: 555 NSRTLDHEVQSSYTFQVAATDGGGRSCNATVHVSLTDLNDNQPVFDPSSYSVEYFENTRI 614 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 G ++ + A D D ++++ I + A D+ F ++ +G IT KLLDRET Sbjct: 615 GQSICQLKAIDRD-----SPKFAITRFIIEQGNA--DEVFSVD-GSGLITLAKLLDRETQ 666 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 YLLTV A DGG + V I+V+DVND P+F + Y I E + + + V Sbjct: 667 DNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQEHSQALSVIGHVH 726 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 A D G N + Y + + + + V+ ++G + +D E + + L A D GT Sbjct: 727 AISRDKGTNAEVVYSISKGNTD--NIVLINSTGTLYLQSEVDHEKIPSLYLTVQAKDKGT 784 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 PP V I + DIND+ P F S + + E++PIG T + D D G V + Sbjct: 785 PPLFGYANVTIAVIDINDNSPQFNSSSILVRLPEDTPIGHTFYTVSVFDADSGVLGRVSF 844 Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVE 781 S+ + F+L++ G+ L ++ DY + + Y L ++A SPP + +E Sbjct: 845 SLL-SNPGTLFNLDSNTGA--LSLTKLI--DYGNSARSYTLPVQAQDGGSPPRSSTAMLE 899 Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD 822 + V DVND +PV ++ + + P V A D D Sbjct: 900 LKVVDVNDYSPVFGNWSYTAHVLETTPPDSNIIEVVATDVD 940 Score = 356 bits (876), Expect = 4e-96 Identities = 272/876 (31%), Positives = 412/876 (47%), Gaps = 60/876 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+ P F+ + E T V T+KA D D G N+ + YTI D+ Sbjct: 1318 IYVEDANDNRPTFDKNPIITWIYENVPINTNVTTIKAHDDDSGLNSRIWYTI-----DSQ 1372 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +P F+I+ +G + T +DRE+++ Y++ V+ATDQA DRL Sbjct: 1373 SPRAH--------------FKINSETGLIQTTHPIDREEISEYSLKVRATDQAFTEQDRL 1418 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +TAT+ + I D NDN P+F + T ++++ N + I A D D G + Y Sbjct: 1419 YNTATLKIIIQDLNDNAPKFVSRNLTYVMEDE---PFNFQVTSITALDPDTGQGGNVEYR 1475 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I+ +T +FS+D +G + L+ +LDYE V Y L I A D GSP ++ + + DV Sbjct: 1476 IVSPDTG-KFSLDLKTGVLKLIGSLDYEDVPQYTLHISATDLGSPPLTSYQLFNVVVVDV 1534 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F LF +VSEN P G S+V+V AYD D G NAELTY++ +G + Sbjct: 1535 NDNPPEFTRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELTYSIP----SGVEMDKFS 1590 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 ID SG + T+ LDRE + Y L V AT P R ++ + F+ Sbjct: 1591 IDKHSGLIVTNSILDREKKDTYFLTVHATGVSYPFRVSSTSVRINVMDRNDNPPKFISPV 1650 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 +++ E+ P + TLT D D N ++ Y I GNT G F+I G ++ Sbjct: 1651 VTLKVPENS-PARLIYTLTVQDLDYGNNTKVLYSIMSGNTDGAFTIGRSTGE--LSTTTK 1707 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYAPVFENAPYTASVFEDAPIGT 486 LD + + Y L+V A D TA I I D N+ PVF+ + Y++++ E P GT Sbjct: 1708 LDRETKASYQLSVQAKDITPPYYTAFANITIFIEDQNDNPPVFQQSLYSSTISELTPPGT 1767 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 ++L ++A+D D G N I Y+LS++ + I+ +TG + + + Sbjct: 1768 SILNLTASDKDSGSNGNIVYTLSNDTYG--------VYSIDSRTGIVYSAARFETSIKQE 1819 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y A+D G V I + D N++ P F + Y +I + V+ V AT Sbjct: 1820 YNFFCIAKDQGQDPKMAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTAT 1879 Query: 607 DADV--GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 DAD NG++ Y LD FV++ +G +RT+ H L +A D G+ Sbjct: 1880 DADTDKSTNGKVTYRLDDSKNSTSLFVVESNTGSVRTSAGFSNPPQGRHALYIIAEDHGS 1939 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDC-LTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 PP IV I I +I D PP F + I ENS +G+ I +RA +A V Sbjct: 1940 PPLRGYGIVQIVIGNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRAR---ASSDAQVT 1996 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR---- 779 YSI G+ +F ++ G + + LDYES K + L + A+P W + Sbjct: 1997 YSIISGNKGRAFYVDPFTG--VISVASADALDYES-TKNFRLHL-VATPQGWVSLNGYMI 2052 Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP--FGRVPAYDAD--VTDKLQYRILSGN 835 ++I V D NDN+P ++ +D P +V A D D K+ Y I +GN Sbjct: 2053 LDINVIDRNDNSPAFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGN 2112 Query: 836 NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 A + ++ TTG +T + L+ + + TD Sbjct: 2113 EAGVFTIDSTTGEITTAKLLDRETTASFDLVIRGTD 2148 Score = 351 bits (863), Expect = 2e-94 Identities = 265/876 (30%), Positives = 396/876 (45%), Gaps = 60/876 (6%) Query: 10 QINVLDCNDHSPVFEMQQY---EASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 +I VLD ND++PV + V E A+ GT V + +D D GKN EV T+E Sbjct: 266 RIEVLDVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTLE--- 322 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 F + + SLDRE + + D+ P Sbjct: 323 --------------GGDGYFSMKFDVLNDESIIAVGQSLDRETHDHFFLKAVCIDKGDPP 368 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 ++ + +N+ D ND P+F TY V E+ +V N ++A + A D D G+NS Sbjct: 369 R---TTEKSFRINVGDVNDCAPKFDRHTYETRVWENATV--NTLVAIVNAVDQDFGSNSE 423 Query: 187 IRYAIIGGNTQMQ----FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 + Y I F+ID SG ++ LD EQ+ L + D GSP S+ Sbjct: 424 LVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCS 483 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 +++N+ D NDN P F S + S+ EN P G +V++ A D D G N+ + Y++ T Sbjct: 484 VIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENSLILYSI----LT 539 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 N P +DPR G V S LD E Q+ Y V ATDGG RS AT Sbjct: 540 PNT--PFFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGGG--RSCNATVHVSLTDLNDN 595 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGR 420 F P Y VE E+ G + L A D D + I GN FS+ +G Sbjct: 596 QPVFDPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQGNADEVFSV---DGS 652 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASV 478 GLIT+A+ LD + + Y+LTV A D GG+ + A+V I + D N+ P+F A Y ++ Sbjct: 653 GLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTI 712 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 E + + + V A D G NA++ YS+S + D +IN TG + Sbjct: 713 QEHSQALSVIGHVHAISRDKGTNAEVVYSISK-------GNTDNIVLIN-STGTLYLQSE 764 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 +D E + LTV A+D G P L +V I+V+D+NDN P F + ED +G Sbjct: 765 VDHEKIPSLYLTVQAKDKGTPPLFGYANVTIAVIDINDNSPQFNSSSILVRLPEDTPIGH 824 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD-RESVATHDLKA 657 + V DAD G+ GR+ + L F +D +G + K +D S ++ L Sbjct: 825 TFYTVSVFDADSGVLGRVSFSL--LSNPGTLFNLDSNTGALSLTKLIDYGNSARSYTLPV 882 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A DGG+PP+SST ++ +K+ D+ND PVF + T ++ E +P + I E+ A D D G Sbjct: 883 QAQDGGSPPRSSTAMLELKVVDVNDYSPVFGNWSYTAHVLETTPPDSNIIEVVATDVDSG 942 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND 777 N + Y+ D++ F L R G K + + +D + + I +P + Sbjct: 943 ENGRISYAFDSKVDTSKFGL--RNGG-KIFIKSKLDREDIEEYNLKVIAIDHGTPRRSSS 999 Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDKLQYRILSGNN 836 V+++V DVNDN P + F K+ PV + G V A D+D Sbjct: 1000 ADVKVIVDDVNDNNPHFQQASYAF-FVKENEPVATYLGAVSASDSDEGSNGHVTYRFDTQ 1058 Query: 837 ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 ++++ TG +T S L+ + TDG Sbjct: 1059 VAQFIVDKQTGKITTSQVLDREAKASYVFSIVATDG 1094 Score = 348 bits (856), Expect = 1e-93 Identities = 271/895 (30%), Positives = 423/895 (47%), Gaps = 59/895 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D ND+SP F ++ A + + L A D D G N+ YTI V+ + Sbjct: 46 VYVQDLNDNSPSF-VRGTSAKLVVFENDKDFRQKLIAVDSDFGSNSTQSYTI--VSGNVG 102 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N D+ ++ S +DRE++ Y + + A+D +P + Sbjct: 103 NVFKLISKRDTDGDLYADLV-VNASS------IGVDRERLDSYVLNISASDGGNPAN--- 152 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + + + D NDN P+FS +Y+ ++ E+I V + I ++ A+D D+G N+ I+Y+ Sbjct: 153 HGFLRLSITVEDTNDNKPEFSNVSYSGTIPENIDVGTS--ILQVSASDKDIGTNAEIQYS 210 Query: 191 I-IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIR 248 I + Q F I +G + LDYE RSY +V++A+D GS + +++ ++ I + Sbjct: 211 IETHSDPQAIFGIHPTTGVIVNNVRLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVL 270 Query: 249 DVNDNAPRF---YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 DVNDN P YT V+EN IG + RV DAD G N E+ T+ D G Sbjct: 271 DVNDNNPVIHVSYTLGGSYQVTENATIGTQVARVSVSDADSGKNGEVNVTLEGGD--GYF 328 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 + + + LDRET + L D GDPPR+ + Sbjct: 329 SMKFDVLNDESIIAVGQSLDRETHDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPK 388 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS----ITSQNGRG 421 F YE + E+ T V + A D D + T NT S G Sbjct: 389 FDRHTYETRVWENATVNTLVAIVNAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSG 448 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVF 479 +IT A LD +Q + VLTV D G SD V +N+TD+N+ P F + Y AS+F Sbjct: 449 MITTATDLDREQIPQVVLTVLVHDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLF 508 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E++P G+ V+ + A D D+G N+ I YS+ + + F ++P+ G +T ++ L Sbjct: 509 ENSPSGSPVVQLLAQDPDIGENSLILYSILTP---------NTPFFLDPRKGLVTNSRTL 559 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 D E S Y V A DGG S + T V +S+ D+NDN+PVF Y+ E+ +G S Sbjct: 560 DHEVQSSYTFQVAATDGGGRSCNAT--VHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQS 617 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 + Q+ A D D + ++ + +E F +D SG+I K LDRE+ + L A Sbjct: 618 ICQLKAIDRDSPKFAITRFIIEQGNADE-VFSVD-GSGLITLAKLLDRETQDNYLLTVKA 675 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 +DGG + IV+I + D+ND PP+F F I E+S + IG + A D+G N Sbjct: 676 VDGGGQDSVNKAIVNITVLDVNDEPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTN 735 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776 A V YSI G+ N + + L ++D+E Y L ++A +PPL+ Sbjct: 736 AEVVYSISKGNTDNIVLI-----NSTGTLYLQSEVDHEKIPSLY-LTVQAKDKGTPPLFG 789 Query: 777 DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILS 833 V I V D+NDN+P I+ +D P+G F V +DAD V ++ + +LS Sbjct: 790 YANVTIAVIDINDNSPQFNSSSILVRLPEDT-PIGHTFYTVSVFDADSGVLGRVSFSLLS 848 Query: 834 GNNANLILLNETTGSMTLSPQLN-TNVPKLATMEVSVTDGVNEIK---AMMQLSV 884 N L L+ TG+++L+ ++ N + T+ V DG + + AM++L V Sbjct: 849 -NPGTLFNLDSNTGALSLTKLIDYGNSARSYTLPVQAQDGGSPPRSSTAMLELKV 902 Score = 339 bits (833), Expect = 7e-91 Identities = 257/856 (30%), Positives = 410/856 (47%), Gaps = 63/856 (7%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDI-GKNAEVEYTIELVTADTLN 71 V D ND SP F +Y +V E G+++LTL ATD D G N+++ Y I Sbjct: 1109 VRDVNDCSPKFSKNKYSVTVNEDLPVGSSLLTLIATDDDQQGPNSDITYMI------VAG 1162 Query: 72 PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131 P+ F ++ +G L + LDRE R+ + V A+D+ S L Sbjct: 1163 PK---------------AFSLNQVTGVLTLVSPLDREVTHRHILHVVASDKGGNQS--LE 1205 Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191 + I +N++D NDNYP F +T +V E + + V+A + A D+D G N +RY I Sbjct: 1206 TITYIEINVLDVNDNYPVFINETTFKTVPEKLPI--GSVVAAVLAVDSDQGDNGKVRYKI 1263 Query: 192 IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIRDV 250 + GNT F I+ +G +S ++ LD+E Y L + A D G + + QL+ I + D Sbjct: 1264 VNGNTDGTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKTSYQLVTIYVEDA 1323 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F + + ENVPI ++ ++A+D D G+N+ + YT+ + + Sbjct: 1324 NDNRPTFDKNPIITWIYENVPINTNVTTIKAHDDDSGLNSRIWYTIDSQSPRAH----FK 1379 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA---TATXXXXXXXXXXXXXXFM 367 I+ +G + T+ +DRE ++Y L V ATD + TAT F+ Sbjct: 1380 INSETGLIQTTHPIDREEISEYSLKVRATDQAFTEQDRLYNTATLKIIIQDLNDNAPKFV 1439 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITV 425 + + EDEP V ++TA D D + + Y I +T G+FS+ + G++ + Sbjct: 1440 -SRNLTYVMEDEPFNFQVTSITALDPDTGQGGNVEYRIVSPDT-GKFSLDLKT--GVLKL 1495 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTASVFEDAP 483 LD++ +Y L +SATD G T+ + + + D N+ P F + +V E+ P Sbjct: 1496 IGSLDYEDVPQYTLHISATDLGSPPLTSYQLFNVVVVDVNDNPPEFTRDLFIGTVSENKP 1555 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 GT+V+ V+A D D G NA++TYS+ S + + +F I+ +G I TN +LDRE Sbjct: 1556 TGTSVVKVTAYDRDSGSNAELTYSIPSGVEMD-------KFSIDKHSGLIVTNSILDREK 1608 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 Y LTV A P +T V I+V+D NDN P F + T + E++ + + Sbjct: 1609 KDTYFLTVHATGVSYPFRVSSTSVRINVMDRNDNPPKFISPVVTLKVPENS-PARLIYTL 1667 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 D D G N ++ Y + +G+F I ++G + T LDRE+ A++ L A D Sbjct: 1668 TVQDLDYGNNTKVLYSI-MSGNTDGAFTIGRSTGELSTTTKLDRETKASYQLSVQAKDIT 1726 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 P ++ + I IED ND+PPVF+ + ISE +P GT+I + A D D G N + Sbjct: 1727 PPYYTAFANITIFIEDQNDNPPVFQQSLYSSTISELTPPGTSILNLTASDKDSGSNGNIV 1786 Query: 724 YSIKGGDDSNSFSLETRQG--SDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781 Y++ D +S+++R G A T + +Y + + P V V Sbjct: 1787 YTL-SNDTYGVYSIDSRTGIVYSAARFETSIKQEYNF----FCIAKDQGQDPKMAIVPVR 1841 Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD----VTDKLQYRI-LSGNN 836 I + D N++AP + + + V A DAD K+ YR+ S N+ Sbjct: 1842 IKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYRLDDSKNS 1901 Query: 837 ANLILLNETTGSMTLS 852 +L ++ TGS+ S Sbjct: 1902 TSLFVVESNTGSVRTS 1917 Score = 327 bits (804), Expect = 2e-87 Identities = 234/796 (29%), Positives = 380/796 (47%), Gaps = 54/796 (6%) Query: 92 IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151 ++ +G + T+ LDREKV+ Y + + + ++P + T+ V + D NDN P F Sbjct: 7 LEYNAGVITTKTVLDREKVSAYNLTI--VEFSTP-----PKSYTVLVYVQDLNDNSPSFV 59 Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS---LSGD 208 T V + D K+ A D+D G+NS Y I+ GN F + S GD Sbjct: 60 RGTSAKLV---VFENDKDFRQKLIAVDSDFGSNSTQSYTIVSGNVGNVFKLISKRDTDGD 116 Query: 209 V--SLVKT-----LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261 + LV +D E++ SY L I A DGG+P+ +L I + D NDN P F Sbjct: 117 LYADLVVNASSIGVDRERLDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVS 176 Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321 + ++ EN+ +G SI++V A D D G NAE+ Y++ + + I P +G + + Sbjct: 177 YSGTIPENIDVGTSILQVSASDKDIGTNAEIQYSI---ETHSDPQAIFGIHPTTGVIVNN 233 Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV----ELAE 377 +LD E + Y ++V A D G + +++ + Y + ++ E Sbjct: 234 VRLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVSYTLGGSYQVTE 293 Query: 378 DEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ--NGRGLITVAQPLDFKQER 435 + GT V ++ +DAD +T G FS+ N +I V Q LD + Sbjct: 294 NATIGTQVARVSVSDADSGKNGEVNVTLEGGDGYFSMKFDVLNDESIIAVGQSLDRETHD 353 Query: 436 RYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 + L D G R+ +IN+ D N+ AP F+ Y V+E+A + T V +V+A Sbjct: 354 HFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIVNA 413 Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553 D D G N+++ Y++++ + + H F I+P +G ITT LDRE + +LTV Sbjct: 414 VDQDFGSNSELVYTIANTTESRSYLHW---FAIDPSSGMITTATDLDREQIPQVVLTVLV 470 Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613 D G P LSD V +++ D NDN+P F Q Y A++ E++ G+ V Q+ A D D+G N Sbjct: 471 HDRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGEN 530 Query: 614 GRIHYE-LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672 I Y L P F +DP G++ ++ LD E +++ + A DGG +S Sbjct: 531 SLILYSILTPNT----PFFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDGG--GRSCNAT 584 Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732 VH+ + D+ND+ PVF+ + EN+ IG +I +++A D D A+ + I+ G+ Sbjct: 585 VHVSLTDLNDNQPVFDPSSYSVEYFENTRIGQSICQLKAIDRDSPKFAITRFIIEQGNAD 644 Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVND 789 FS+ D + L+T+ L + Y L ++A N V I V DVND Sbjct: 645 EVFSV------DGSGLITLAKLLDRETQDNYLLTVKAVDGGGQDSVNKAIVNITVLDVND 698 Query: 790 NAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTG 847 P+ + F + + G V A D ++ Y I GN N++L+N +TG Sbjct: 699 EPPIFSKAEYNFTIQEHSQALSVIGHVHAISRDKGTNAEVVYSISKGNTDNIVLIN-STG 757 Query: 848 SMTLSPQL-NTNVPKL 862 ++ L ++ + +P L Sbjct: 758 TLYLQSEVDHEKIPSL 773 Score = 310 bits (761), Expect = 4e-82 Identities = 252/856 (29%), Positives = 390/856 (45%), Gaps = 59/856 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +INVLD ND+ PVF + +V E G+ V + A D D G N +V Y ++V +T Sbjct: 1211 EINVLDVNDNYPVFINETTFKTVPEKLPIGSVVAAVLAVDSDQGDNGKVRY--KIVNGNT 1268 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 F+I+ +G + T +LD E RY + V ATD Sbjct: 1269 -----------------DGTFKINETTGVISTLRALDFEVTNRYVLRVSATDMGKKQQKT 1311 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 TI+V D NDN P F + + E++ + N + IKA D D G NS I Y Sbjct: 1312 SYQLVTIYVE--DANDNRPTFDKNPIITWIYENVPINTN--VTTIKAHDDDSGLNSRIWY 1367 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS---NTTQLLIN 246 I + + F I+S +G + +D E++ Y L +RA D + NT L I Sbjct: 1368 TIDSQSPRAHFKINSETGLIQTTHPIDREEISEYSLKVRATDQAFTEQDRLYNTATLKII 1427 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 I+D+NDNAP+F S V E+ P + + + A D D G + Y + D TG Sbjct: 1428 IQDLNDNAPKF-VSRNLTYVMEDEPFNFQVTSITALDPDTGQGGNVEYRIVSPD-TGK-- 1483 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 ++D ++G + G LD E +Y L ++ATD G PP ++ F Sbjct: 1484 --FSLDLKTGVLKLIGSLDYEDVPQYTLHISATDLGSPPLTSYQLFNVVVVDVNDNPPEF 1541 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLIT 424 + ++E++P GT VV +TA D D + L Y I G +FSI + GLI Sbjct: 1542 TRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELTYSIPSGVEMDKFSIDKHS--GLIV 1599 Query: 425 VAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 LD +++ Y LTV AT R + V+IN+ D N+ P F + T V E++ Sbjct: 1600 TNSILDREKKDTYFLTVHATGVSYPFRVSSTSVRINVMDRNDNPPKFISPVVTLKVPENS 1659 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 P + ++ D D G N ++ YS+ S + D F I TG ++T LDRE Sbjct: 1660 P-ARLIYTLTVQDLDYGNNTKVLYSIMS-------GNTDGAFTIGRSTGELSTTTKLDRE 1711 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 T + Y L+V A+D P + ++ I + D NDN PVF+Q LY++ I E GTS+ Sbjct: 1712 TKASYQLSVQAKDITPPYYTAFANITIFIEDQNDNPPVFQQSLYSSTISELTPPGTSILN 1771 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 + A+D D G NG I Y L + G + ID +G++ + + ++ +A D Sbjct: 1772 LTASDKDSGSNGNIVYTL--SNDTYGVYSIDSRTGIVYSAARFETSIKQEYNFFCIAKDQ 1829 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA--HDPDEGPNA 720 G P+ + V V IKIED N+ P F +I N+ + + A D D+ N Sbjct: 1830 GQDPKMAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNG 1889 Query: 721 VVHYSIKGGDDSNS-FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776 V Y + +S S F +E+ GS + T P+ ++ L I A SPPL Sbjct: 1890 KVTYRLDDSKNSTSLFVVESNTGSVR----TSAGFS-NPPQGRHALYIIAEDHGSPPLRG 1944 Query: 777 DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNN 836 V+I++ ++ D+ P + + + VG + A ++ Y I+SGN Sbjct: 1945 YGIVQIVIGNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRARASSDAQVTYSIISGNK 2004 Query: 837 ANLILLNETTGSMTLS 852 ++ TG ++++ Sbjct: 2005 GRAFYVDPFTGVISVA 2020 Score = 302 bits (741), Expect = 1e-79 Identities = 226/729 (31%), Positives = 347/729 (47%), Gaps = 58/729 (7%) Query: 2 SVPFCIHQQINVL--DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVE 59 S P +Q NV+ D ND+ P F + +V E +GT+V+ + A D+D G NAE+ Sbjct: 1518 SPPLTSYQLFNVVVVDVNDNPPEFTRDLFIGTVSENKPTGTSVVKVTAYDRDSGSNAELT 1577 Query: 60 YTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKA 119 Y+I P D F ID SG ++T + LDREK Y + V A Sbjct: 1578 YSI---------PSGVE----------MDKFSIDKHSGLIVTNSILDREKKDTYFLTVHA 1618 Query: 120 TDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA 179 T + P R+SST ++ +N++D NDN P+F T+ V E+ + +I + D Sbjct: 1619 TGVSYPF--RVSST-SVRINVMDRNDNPPKFISPVVTLKVPEN---SPARLIYTLTVQDL 1672 Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239 D G N+ + Y+I+ GNT F+I +G++S LD E SY+L ++A+D P + Sbjct: 1673 DYGNNTKVLYSIMSGNTDGAFTIGRSTGELSTTTKLDRETKASYQLSVQAKDITPPYYTA 1732 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 + I I D NDN P F SL+ ++SE P G SI+ + A D D G N + YT+++ Sbjct: 1733 FANITIFIEDQNDNPPVFQQSLYSSTISELTPPGTSILNLTASDKDSGSNGNIVYTLSND 1792 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 Y +ID R+G VY++ + + + +Y A D G P+ A Sbjct: 1793 TYG-----VYSIDSRTGIVYSAARFETSIKQEYNFFCIAKDQGQDPKMAIVPVRIKIEDK 1847 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT-----GGNTRGRFSI 414 F YEV + + V +TATDAD D + ++T N+ F + Sbjct: 1848 NNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYRLDDSKNSTSLFVV 1907 Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFEN- 471 S G + + + R+ L + A D G +VQI I + + P F N Sbjct: 1908 ESNTGS--VRTSAGFSNPPQGRHALYIIAEDHGSPPLRGYGIVQIVIGNIQDDPPRFLNQ 1965 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 P S+ E++ +G+ + V A S +AQ+TYS+ S + + F ++P TG Sbjct: 1966 TPARVSIPENSKVGSYITTVRARASS---DAQVTYSIIS-------GNKGRAFYVDPFTG 2015 Query: 532 AIT--TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589 I+ + LD E+ + L + A G SL+ ++I+V+D NDN P F A Sbjct: 2016 VISVASADALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSPAFHPSNMLAQ 2075 Query: 590 IMED--ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647 + ED A V +V ATD D G NG++ Y + E G F ID +G I T K LDR Sbjct: 2076 LAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSI-WTGNEAGVFTIDSTTGEITTAKLLDR 2134 Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 E+ A+ DL D G PP+S+ V + + D+ND+PP+F+ I E++ G + Sbjct: 2135 ETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFD-PLSEVNIREDTRTGAVVT 2193 Query: 708 EIRAHDPDE 716 + A D D+ Sbjct: 2194 SVVATDTDK 2202 Score = 300 bits (737), Expect = 3e-79 Identities = 246/844 (29%), Positives = 389/844 (46%), Gaps = 58/844 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I + D ND++P F + V E V ++ A D D G+ VEY I V+ DT Sbjct: 1425 KIIIQDLNDNAPKFVSRNL-TYVMEDEPFNFQVTSITALDPDTGQGGNVEYRI--VSPDT 1481 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 F +D ++G L SLD E V +YT+ + ATD SP Sbjct: 1482 ------------------GKFSLDLKTGVLKLIGSLDYEDVPQYTLHISATDLGSPP--- 1520 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L+S +V ++D NDN P+F+ + +V E+ T V+ K+ A D D G+N+ + Y Sbjct: 1521 LTSYQLFNVVVVDVNDNPPEFTRDLFIGTVSEN-KPTGTSVV-KVTAYDRDSGSNAELTY 1578 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 +I G +FSID SG + LD E+ +Y L + A P R ++T + IN+ D Sbjct: 1579 SIPSGVEMDKFSIDKHSGLIVTNSILDREKKDTYFLTVHATGVSYPFRVSSTSVRINVMD 1638 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 NDN P+F + + V EN P I + D D G N ++ Y++ +GN D Sbjct: 1639 RNDNPPKFISPVVTLKVPENSPARL-IYTLTVQDLDYGNNTKVLYSIM----SGNTDGAF 1693 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 TI +G + T+ +LDRET+A YQL V A D P +A A F Sbjct: 1694 TIGRSTGELSTTTKLDRETKASYQLSVQAKDITPPYYTAFANITIFIEDQNDNPPVFQQS 1753 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGN-TRGRFSITSQNGRGLITVAQP 428 Y ++E PPGT ++ LTA+D D + + T N T G +SI S+ G Sbjct: 1754 LYSSTISELTPPGTSILNLTASDKDSGSNGNIVYTLSNDTYGVYSIDSRTGIVYSAARFE 1813 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 KQE + + V+I I D NN+AP F PY +F + V Sbjct: 1814 TSIKQEYNFFCIAKDQGQDPKMAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALV 1873 Query: 489 LVVSATDSDV--GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 +V+ATD+D N ++TY L ++ ++ FV+ TG++ T+ Sbjct: 1874 TMVTATDADTDKSTNGKVTYRLDDSKNSTSL------FVVESNTGSVRTSAGFSNPPQGR 1927 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT-ANIMEDALVGTSVSQVGA 605 + L + A D G P L V+I + ++ D+ P F Q +I E++ VG+ ++ V A Sbjct: 1928 HALYIIAEDHGSPPLRGYGIVQIVIGNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRA 1987 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA--LDRESVATHDLKAVAIDGG 663 + + ++ Y + ++ +F +DP +GVI A LD ES L VA G Sbjct: 1988 RASS---DAQVTYSIISGNKGR-AFYVDPFTGVISVASADALDYESTKNFRLHLVATPQG 2043 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT--IGEIRAHDPDEGPNAV 721 + +I+ I + D ND+ P F + ++E++ + ++ A D D G N Sbjct: 2044 WVSLNGYMILDINVIDRNDNSPAFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGK 2103 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDV 778 V YSI G+++ F++++ G E+ T LD E+ ++LVIR PP + Sbjct: 2104 VTYSIWTGNEAGVFTIDSTTG----EITTAKLLDRETTAS-FDLVIRGTDSGIPPKSTNC 2158 Query: 779 RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNAN 838 +V+++VTD+NDN P+ + N +D V A D D +L Y + S + Sbjct: 2159 QVKVVVTDLNDNPPLFDPLSEV-NIREDTRTGAVVTSVVATDTDKESRLTYNLKSASTPG 2217 Query: 839 LILL 842 + +L Sbjct: 2218 IAIL 2221 Score = 272 bits (667), Expect = 9e-71 Identities = 260/893 (29%), Positives = 398/893 (44%), Gaps = 112/893 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D ND+ PVF+ Y +++ E GT++L L A+D+D G N + YT+ + DT Sbjct: 1738 IFIEDQNDNPPVFQQSLYSSTISELTPPGTSILNLTASDKDSGSNGNIVYTL---SNDTY 1794 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 V+ ID R+G + + A + Y A DQ D Sbjct: 1795 G-----------------VYSIDSRTGIVYSAARFETSIKQEYNFFCIAKDQGQ---DPK 1834 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV--GANSAIR 188 + + + I D N++ PQF++ Y V + + S + ++ + ATDAD N + Sbjct: 1835 MAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSAS--ALVTMVTATDADTDKSTNGKVT 1892 Query: 189 YAIIGG-NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 Y + N+ F ++S +G V + L I A+D GSP + I I Sbjct: 1893 YRLDDSKNSTSLFVVESNTGSVRTSAGFSNPPQGRHALYIIAEDHGSPPLRGYGIVQIVI 1952 Query: 248 RDVNDNAPRFYTSL-FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 ++ D+ PRF + S+ EN +G I V+A + + A++TY++ +GN Sbjct: 1953 GNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRARASSD---AQVTYSII----SGNKG 2005 Query: 307 LPITIDPRSGW--VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 +DP +G V ++ LD E+ ++L + AT G + Sbjct: 2006 RAFYVDPFTGVISVASADALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSP 2065 Query: 365 XFMPGQYEVELAEDEPPGTP--VVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGR 420 F P +LAED P VV +TATD D + ++ Y I GN G F+I S G Sbjct: 2066 AFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGNEAGVFTIDSTTGE 2125 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANN----YAPVFE---- 470 IT A+ LD + + L + TDSG +S V++ +TD N+ + P+ E Sbjct: 2126 --ITTAKLLDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFDPLSEVNIR 2183 Query: 471 -----NAPYTASVFED--------------APIGTTVLVVSATDSDVGINAQITYSLSSE 511 A T+ V D + G +L VSATD D G NAQI YS Sbjct: 2184 EDTRTGAVVTSVVATDTDKESRLTYNLKSASTPGIAILRVSATDQDSGSNAQIKYSFP-- 2241 Query: 512 ISNEAVAHHDQ-QFVINPQTGAITTNKLLDRETMSGYL-LTVTARDGGVPSLSDTTDVEI 569 + + DQ + I+ TG I+ + +D ++ + V A D GVP V I Sbjct: 2242 -----ITNSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPPQRALVYVRI 2296 Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN-GRIHYELDPKDREEG 628 + EP F+ Y + E+A++GTSV V TD GL GRI Y ++ Sbjct: 2297 IIT----REPKFELPSYFGKVPENAMMGTSVLTVRVTDNAAGLPLGRISYNIE----NSN 2348 Query: 629 SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688 F I SGVI NK LD E+ L AID P + V V+I + D+ND PVF Sbjct: 2349 YFRIGQRSGVISVNKPLDYETKRRFLLVVSAIDDTAPSKPVRVPVYINVSDVNDEKPVFG 2408 Query: 689 SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAEL 748 SE P+GT + + A D D G N V ++I+ GDD SF+++ + G + Sbjct: 2409 QSGYMAQWSEGIPVGTIVVNVSAADKDSGANGRVWFAIQSGDDKGSFAIDRKTG----VI 2464 Query: 749 VTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMK-----DFQII 800 T LD+E+ K + + +RA SPP+ DV V I V D+NDN PV + D Q++ Sbjct: 2465 RTQRALDHET-IKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRVPGPNDVQVL 2523 Query: 801 FNNYKDCFPVGP-FGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMT 850 N P+ + A D D +L + ++ G L L+++ +G +T Sbjct: 2524 EN-----LPLNSRLYEINATDRDSGANARLSFTVIGGTGQGLFLIDKFSGWLT 2571 Score = 266 bits (651), Expect = 8e-69 Identities = 206/691 (29%), Positives = 321/691 (46%), Gaps = 62/691 (8%) Query: 90 FRIDGRSGALLTRAS--LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 F +D +G + ++ LD E + + + AT Q VS L+ + +N+ID NDN Sbjct: 2008 FYVDPFTGVISVASADALDYESTKNFRLHLVATPQGW-VS--LNGYMILDINVIDRNDNS 2064 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 P F + ED + K+ ATD D G N + Y+I GN F+IDS +G Sbjct: 2065 PAFHPSNMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWTGNEAGVFTIDSTTG 2124 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 +++ K LD E S+ LVIR D G P +S Q+ + + D+NDN P + L + ++ Sbjct: 2125 EITTAKLLDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPP-LFDPLSEVNIR 2183 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTM---------------TDKDYTGNVDL----P 308 E+ G + V A D D+ + LTY + TD+D N + P Sbjct: 2184 EDTRTGAVVTSVVATDTDK--ESRLTYNLKSASTPGIAILRVSATDQDSGSNAQIKYSFP 2241 Query: 309 IT--------IDPRSGWVYTSGQLDRETQAKY-QLLVTATDGGDPPRSATATXXXXXXXX 359 IT ID +G + +D + + Q+ V A D G PP+ A Sbjct: 2242 ITNSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPPQRALV----YVRII 2297 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED---NRLHYEITGGNTRGRFSITS 416 F Y ++ E+ GT V+T+ TD R+ Y I N F I Sbjct: 2298 ITREPKFELPSYFGKVPENAMMGTSVLTVRVTDNAAGLPLGRISYNIENSNY---FRIGQ 2354 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ--INITDANNYAPVFENAPY 474 ++G +I+V +PLD++ +RR++L VSA D S V IN++D N+ PVF + Y Sbjct: 2355 RSG--VISVNKPLDYETKRRFLLVVSAIDDTAPSKPVRVPVYINVSDVNDEKPVFGQSGY 2412 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 A E P+GT V+ VSA D D G N ++ +++ S F I+ +TG I Sbjct: 2413 MAQWSEGIPVGTIVVNVSAADKDSGANGRVWFAIQS-------GDDKGSFAIDRKTGVIR 2465 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ-LYTANIMED 593 T + LD ET+ + ++V A D G P + V I V+D+NDN PVF+ ++E+ Sbjct: 2466 TQRALDHETIKTHHVSVRATDEGSPPMHTDVSVTIRVLDLNDNPPVFRVPGPNDVQVLEN 2525 Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653 + + + ++ ATD D G N R+ + + +G F+ID SG + TN D E+ A + Sbjct: 2526 LPLNSRLYEINATDRDSGANARLSFTVIG-GTGQGLFLIDKFSGWLTTNITFDYENTAVY 2584 Query: 654 D--LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711 L A D G PP SS + + + + D ++ P F F + N+ IG +G++ A Sbjct: 2585 QYSLTIKATDAGNPPLSSNITIIVNVADEDEYDPSFNRMDYKFDVPGNAKIGDFVGQVTA 2644 Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 D D G V + + SN+ + G Sbjct: 2645 TDRDSGDQGRVFF-VFYNPTSNALKMNATTG 2674 Score = 242 bits (592), Expect = 1e-61 Identities = 251/933 (26%), Positives = 396/933 (42%), Gaps = 96/933 (10%) Query: 1 MSVPFCIHQ---QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAE 57 +S PF + +INV+D ND+ P F V E S + TL D D G N + Sbjct: 1621 VSYPFRVSSTSVRINVMDRNDNPPKFISPVVTLKVPEN-SPARLIYTLTVQDLDYGNNTK 1679 Query: 58 VEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLV 117 V Y+I D F I +G L T LDRE A Y + V Sbjct: 1680 VLYSIMSGNTD-------------------GAFTIGRSTGELSTTTKLDRETKASYQLSV 1720 Query: 118 KATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKAT 177 +A D P ++ A I + I D NDN P F + Y+ ++ E I + A+ Sbjct: 1721 QAKDITPPY---YTAFANITIFIEDQNDNPPVFQQSLYSSTISE--LTPPGTSILNLTAS 1775 Query: 178 DADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237 D D G+N I Y + +T +SIDS +G V + + Y A+D G + Sbjct: 1776 DKDSGSNGNIVYTL-SNDTYGVYSIDSRTGIVYSAARFETSIKQEYNFFCIAKDQGQDPK 1834 Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD--EGVNAELTYT 295 + I I D N++AP+F + ++ + N + V A DAD + N ++TY Sbjct: 1835 MAIVPVRIKIEDKNNHAPQFTKTPYEVHIFPNTSASALVTMVTATDADTDKSTNGKVTYR 1894 Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355 + D + ++ ++ +G V TS Q ++ L + A D G PP Sbjct: 1895 LDDSKNSTSL---FVVESNTGSVRTSAGFSNPPQGRHALYIIAEDHGSPPLRGYGIVQIV 1951 Query: 356 XXXXXXXXXXFM-PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSI 414 F+ V + E+ G+ + T+ A A D ++ Y I GN F + Sbjct: 1952 IGNIQDDPPRFLNQTPARVSIPENSKVGSYITTVRAR-ASSDAQVTYSIISGNKGRAFYV 2010 Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENA 472 G + A LD++ + + L + AT G S ++ IN+ D N+ +P F + Sbjct: 2011 DPFTGVISVASADALDYESTKNFRLHLVATPQGWVSLNGYMILDINVIDRNDNSPAFHPS 2070 Query: 473 PYTASVFEDAPIGTT--VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 A + ED V+ V+ATD D G N ++TYS+ + NEA F I+ T Sbjct: 2071 NMLAQLAEDTGAFKPRFVVKVTATDVDSGTNGKVTYSIWT--GNEAGV-----FTIDSTT 2123 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV-------------DVNDN 577 G ITT KLLDRET + + L + D G+P S V++ V +VN Sbjct: 2124 GEITTAKLLDRETTASFDLVIRGTDSGIPPKSTNCQVKVVVTDLNDNPPLFDPLSEVNIR 2183 Query: 578 EPVF--------------KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK 623 E K+ T N+ + G ++ +V ATD D G N +I Y Sbjct: 2184 EDTRTGAVVTSVVATDTDKESRLTYNLKSASTPGIAILRVSATDQDSGSNAQIKYSFPIT 2243 Query: 624 DREEGSFVIDPASGVIRTNKALD-RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND 682 + ++ + ID +GVI + +D R + + A+D G PPQ + V V I I Sbjct: 2244 NSDQIDYKIDADTGVISARRTIDVRIRDSFIQIPVQAMDQGVPPQRALVYVRI----IIT 2299 Query: 683 SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG-PNAVVHYSIKGGDDSNSFSLETRQ 741 P FE + EN+ +GT++ +R D G P + Y+I ++SN F + R Sbjct: 2300 REPKFELPSYFGKVPENAMMGTSVLTVRVTDNAAGLPLGRISYNI---ENSNYFRIGQRS 2356 Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQ 798 G + LDYE+ ++++ LV+ A +P V V I V+DVND PV Sbjct: 2357 G----VISVNKPLDYET-KRRFLLVVSAIDDTAPSKPVRVPVYINVSDVNDEKPVFGQSG 2411 Query: 799 IIFNNYKDCFPVGPF-GRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQL 855 + + + PVG V A D D ++ + I SG++ ++ TG + L Sbjct: 2412 YM-AQWSEGIPVGTIVVNVSAADKDSGANGRVWFAIQSGDDKGSFAIDRKTGVIRTQRAL 2470 Query: 856 NTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLI 887 + K + V TD G + + +++R++ Sbjct: 2471 DHETIKTHHVSVRATDEGSPPMHTDVSVTIRVL 2503 Score = 227 bits (554), Expect = 4e-57 Identities = 172/587 (29%), Positives = 276/587 (47%), Gaps = 34/587 (5%) Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 +P ++ +G + T LDRE + Y L T + PP+S T F Sbjct: 3 IPADLEYNAGVITTKTVLDREKVSAYNL--TIVEFSTPPKSYTV--LVYVQDLNDNSPSF 58 Query: 367 MPG-QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG------ 419 + G ++ + E++ + +D ++ Y I GN F + S+ Sbjct: 59 VRGTSAKLVVFENDKDFRQKLIAVDSDFGSNSTQSYTIVSGNVGNVFKLISKRDTDGDLY 118 Query: 420 RGLITVAQPLDFKQER--RYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYT 475 L+ A + +ER YVL +SA+D G ++ ++++IT D N+ P F N Y+ Sbjct: 119 ADLVVNASSIGVDRERLDSYVLNISASDGGNPANHGFLRLSITVEDTNDNKPEFSNVSYS 178 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 ++ E+ +GT++L VSA+D D+G NA+I YS+ + +A+ F I+P TG I Sbjct: 179 GTIPENIDVGTSILQVSASDKDIGTNAEIQYSIETHSDPQAI------FGIHPTTGVIVN 232 Query: 536 NKLLDRETMSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA----NI 590 N LD E YL+ V A D G LS + V I V+DVNDN PV YT + Sbjct: 233 NVRLDYEAKRSYLIVVKAEDKGSSHQLSSSAIVRIEVLDVNDNNPVIHVS-YTLGGSYQV 291 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNKALDRES 649 E+A +GT V++V +DAD G NG ++ L+ D F + +I ++LDRE+ Sbjct: 292 TENATIGTQVARVSVSDADSGKNGEVNVTLEGGDGYFSMKFDVLNDESIIAVGQSLDRET 351 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 LKAV ID G PP+++ I + D+ND P F+ + EN+ + T + + Sbjct: 352 HDHFFLKAVCIDKGDPPRTTEKSFRINVGDVNDCAPKFDRHTYETRVWENATVNTLVAIV 411 Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES-PRKKYELVIR 768 A D D G N+ + Y+I +S S+ + T DLD E P+ +++ Sbjct: 412 NAVDQDFGSNSELVYTIANTTESRSYLHWFAIDPSSGMITTATDLDREQIPQVVLTVLVH 471 Query: 769 -AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK- 826 SPPL ++ V + +TD NDN P + +++ P ++ A D D+ + Sbjct: 472 DRGSPPLSDNCSVIVNLTDSNDNDPYFNQSSYNASLFENSPSGSPVVQLLAQDPDIGENS 531 Query: 827 -LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 + Y IL+ N L+ G +T S L+ V T +V+ TDG Sbjct: 532 LILYSILTPNTP--FFLDPRKGLVTNSRTLDHEVQSSYTFQVAATDG 576 >UniRef50_UPI00015A700B Cluster: UPI00015A700B related cluster; n=1; Danio rerio|Rep: UPI00015A700B UniRef100 entry - Danio rerio Length = 3528 Score = 378 bits (931), Expect = e-103 Identities = 250/804 (31%), Positives = 411/804 (51%), Gaps = 67/804 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+V+D ND+SPV M + ++E + +GT V + D D GKN +V +E + T+ Sbjct: 927 IDVVDVNDNSPVISMTSFSGKIQEDSPAGTVVALISVQDLDSGKNGQVRLALEQSSPFTI 986 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P L+T A LDREKV+ + + + ATD+ SP L Sbjct: 987 KPSPRKYYT-------------------LVTDAPLDREKVSSFNLTLVATDEGSP---SL 1024 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S TI +++ D NDN P FS++ Y V E+ S + ++A+D D G N+ I Y Sbjct: 1025 FSKITISLDVTDINDNAPVFSQREYKAYVMENNS--PGVSLLTLQASDPDAGQNARIAYY 1082 Query: 191 II-----GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 +I G FS+++ +G + V++ DYEQ++ +++ +RAQDGGSP + ++I Sbjct: 1083 LIDSDVNGSPVSSHFSVNADNGIIHAVRSFDYEQMKEFKIHVRAQDGGSPPLCSNATVVI 1142 Query: 246 NIRDVNDNAPRFY------TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 N++D NDNAP+ S+ E V + +GY + +V A D D G NA L+Y + Sbjct: 1143 NVQDQNDNAPQVLYPVQSGASVVAEIVPRSADVGYLVTKVVAVDVDSGQNAWLSYKL--- 1199 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 + + ++G + T Q + +L+ A DGG+P RS + Sbjct: 1200 -HKATDRALFEVGAQNGEIRTVRQESADDHDSLKLI--AVDGGNPQRSGSVIIDVTVLDA 1256 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEI--TGGNTRGRFSIT 415 F Y + E+ P GT + T+ ATDAD + R+ Y G F+I Sbjct: 1257 NDNAPVFNQTVYRASVMENAPKGTYITTVNATDADAGSYGRITYNFYKQKGAAAQLFNID 1316 Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYT 475 S G +I+V +D +++ ++ LTV A D GG +D++ + +++ D N+ APV ++ Sbjct: 1317 SNTG--IISVVGEIDHEKDTKFELTVEARDQGGLTDSSKITLDVIDVNDNAPVINAMSFS 1374 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 ++V EDAP TT+ +++ D+D N ++ S E S + V + ++ T Sbjct: 1375 STVSEDAPPDTTIAIINVKDADTDDNGRV--SCFIEGSEDFVVKSTLR-----NYYSLVT 1427 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 N +LDRE +S Y +TV A D G P L+ + VVDVNDN PVF++++Y + + E+ Sbjct: 1428 NVILDREKLSEYNITVVATDSGKPPLTSRKTFNLKVVDVNDNAPVFRERVYNSYLPENNS 1487 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV-IDPASGVIRTNKALDRESVATHD 654 G S+ ++ A D D N RI Y L+ D G++V ++ SGV+ ++ D E + Sbjct: 1488 PGVSILRIRAHDPDENQNARISYILEESDL--GTYVSVNAESGVVHAVRSFDYEQIKNIK 1545 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 + A DGG+PP SS V + + + D+ND+ PVF ++EN+P GT I + A D Sbjct: 1546 VTVKAQDGGSPPLSSNVTIDVTVLDVNDNAPVFNQTVYRASVTENAPKGTYITTVNATDA 1605 Query: 715 DEGPNAVVHYSIKGGDDSNS--FSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRAAS 771 D G N + S + + F+++ G LV+++ ++D+E K++E+ ++A Sbjct: 1606 DSGSNGHITLSFSDLKEQSRGIFNIDENTG-----LVSVLGNIDFEKD-KRFEIRVKATD 1659 Query: 772 P-PLWNDVRVEILVTDVNDNAPVM 794 L + ++ I V DVNDNAPV+ Sbjct: 1660 QGGLTSTSKLIIEVVDVNDNAPVI 1683 Score = 375 bits (923), Expect = e-102 Identities = 263/806 (32%), Positives = 404/806 (50%), Gaps = 63/806 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVR-EGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 + + D ND++PVFE Y+ASV+ E A +G V+ + ATD D G N E+ Y+ + Sbjct: 2759 LQISDVNDNAPVFEQSSYQASVQFENAPNGAVVVRVSATDNDQGANGEITYSFSRSSGKN 2818 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L D+F I +G + + LD E+ ++ + + ATD+ Sbjct: 2819 L-----------------DLFHIGPDTGEITVKGHLDYERAKQFELNIDATDKGG----- 2856 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L+ ++ + ++I D NDN P S +++ + ED + VIA + D D G N ++ Sbjct: 2857 LTDSSKVIIDITDVNDNPPVISLISFSNPIPEDAA--PETVIAMLNVKDLDSGKNGQVKC 2914 Query: 190 AIIGGNTQMQFSIDSLSGDV-SLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 I + M F + S + + SL+ + LD E++ Y + + A D GSPS S L + Sbjct: 2915 YI---SADMPFKVKSSAQNFYSLITDQLLDREKISEYNITVTATDEGSPSFSTNKTLTLK 2971 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 I DVNDNAP F + + EN G S++ V+A+D D G NA ++Y + D Sbjct: 2972 ISDVNDNAPVFERQSYTAFIIENNSPGVSVLSVKAHDRDSGNNARISYFLDLSGSEHGND 3031 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 ++ + LDRETQ +++L +TA DGG+P R+ T F Sbjct: 3032 GSKYVE-----MVLQAPLDRETQHEHKLTLTAFDGGNPQRTGTVRICVTVIDANDNAPVF 3086 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEIT--GGNTRGRFSITSQNGR-- 420 Y V L E+ P G VV ++ATD D+ + + Y + G F I + G Sbjct: 3087 SLPVYRVSLFENAPNGAVVVRVSATDNDQGANGEITYSFSRSSGKNLDLFHIGADTGEIT 3146 Query: 421 ---GLITVAQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYT 475 LIT Q LD ++ Y +TV+ATD G S + + + I+D N+ APVFE YT Sbjct: 3147 NFYSLIT-DQLLDREKISEYNITVTATDEGSPSFSTNKTLTLKISDVNDNAPVFERQSYT 3205 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV-INPQTGAIT 534 A + E+ G +VL V A D D G NA+I+Y L + N A F+ +N ++G I Sbjct: 3206 AFIMENNSPGVSVLSVKAHDRDSGNNARISYFLEDVVVNGVSA---STFISVNAESGEIL 3262 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 + D E + + V A+DGG P LS +++ + V+D NDN P F Q +Y A+I E+ Sbjct: 3263 AARSFDYEQTKDFSIRVKAQDGGSPPLS--SNINVIVLDANDNAPAFSQSVYKASIPENF 3320 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNKA---LDRESV 650 G+SV +V A D D G NG + Y L G F ID +G I N LDRE + Sbjct: 3321 SKGSSVLKVSAADGDTGSNGEVTYSLSQSSESFSGLFNIDSNTGDITVNVTDDLLDREML 3380 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710 + +++ A D G+P S+ + +KI D+ND+ PVFE T +I EN+ G ++ ++ Sbjct: 3381 SEYNITVTATDEGSPSFSTNKTLTLKISDVNDNAPVFERQSYTAFIMENNSPGVSVLSVK 3440 Query: 711 AHDPDEGPNAVVHYSIKG-GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 AHD D G NA + Y ++ + S S ++ E++ DYE K + + ++A Sbjct: 3441 AHDRDSGNNARISYFLEDVVVNGVSASTFISVHAESGEILAARSFDYEQ-TKDFSIRVKA 3499 Query: 770 ---ASPPLWNDVRVEILVTDVNDNAP 792 SPPL ++V V+IL+ D NDNAP Sbjct: 3500 QDGGSPPLSSNVSVKILIQDQNDNAP 3525 Score = 375 bits (922), Expect = e-101 Identities = 272/888 (30%), Positives = 429/888 (48%), Gaps = 69/888 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I++ D ND++PVFE Y+ASV+ A G V + A D D G+NA + Y + T L Sbjct: 2008 IDISDVNDNAPVFEQSSYQASVQRSADVGYLVTKVVAVDVDSGQNAWLSYKLHKATDRAL 2067 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLT--RASLDREKVARYTVLVKATDQASPVSD 128 F + ++G + T + LDREK +++ A D P Sbjct: 2068 -------------------FEVGAQNGEIRTVRQKPLDREKQNEINLVLTAVDGGDP--- 2105 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 +LS + IH+ ++D NDN P F + Y +V E+ + +++ + ATDAD G NS I Sbjct: 2106 QLSGSIDIHITVLDANDNAPVFMQSVYKATVTEN--APKDTIVSTVSATDADEGINSKIE 2163 Query: 189 YAIIG--GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT-TQLLI 245 Y+I N + F I+ +G V +V +D+E+ R+Y + ++A D S S+S T++++ Sbjct: 2164 YSIANRQDNVRQLFDINKDNGQVRVVGIIDFEKARNYEISVQASDHLSGSKSEPLTEVIL 2223 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK-DYTGN 304 D NDNAP ++++ S++EN P G + V A DAD+G N+ +T++++ D + Sbjct: 2224 EFLDANDNAPVCSQTVYKTSIAENSPKGTVLTTVSASDADQGSNSRITFSISSTADKAAD 2283 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 + ID G V +G +D E + + + DGGDP S + Sbjct: 2284 I---FEIDSELGVVKLTGGIDYEQRHSLLTDIRSVDGGDPQLSGSIDIHITVLDVNDNAP 2340 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGL 422 FM Y+ + E+ P T V T++ATDADE ++++ Y I + SI S R L Sbjct: 2341 VFMQSVYKATVTENAPKDTIVSTVSATDADEGINSKIEYSIANIDNGQSVSIQSYYSREL 2400 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFE 480 + + + +L +A D G S TA + I + DAN+ APVF Y AS+ E Sbjct: 2401 -----GKGHRVDHKNILYKNAIDGGDPQLSGTAQIHITVLDANDNAPVFTQKIYKASITE 2455 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 +A GT + VSA+D D G +ITY++++ + + V F IN G + +D Sbjct: 2456 NAVRGTVITTVSASDLDEGSYGKITYAITNTLDDVPVL-----FEINETNGEVRVIGTVD 2510 Query: 541 RETMSGYLLTVTARDGG--VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 E Y + V A D G S D+ I+V+D NDN PVF ++Y A+I E+A+ GT Sbjct: 2511 YEKARHYQIHVQASDDGGLTDSCKIDVDIHITVLDANDNAPVFTHKIYKASITENAVRGT 2570 Query: 599 SVSQVGATDADVGLNGRIHYEL-DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 ++ V A+D D G G+I Y + + F I+ +G I+T + + Sbjct: 2571 IITTVTASDLDEGSYGKITYAITNSLGNFPMLFEINETNGEIQTREKMITLENPMEFYSI 2630 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A+DGG P S T+ + I +ED ND+ P+ ++ENSP GT + ++A D D+G Sbjct: 2631 TAVDGGDPQLSGTIPIIITVEDANDNAPICFMSVYKTSVAENSPKGTVLTTVKASDADQG 2690 Query: 718 PNAVVHYSI--KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW 775 N V Y I G N F ++ G K D+DYE K Y++ ++A P Sbjct: 2691 QNGKVEYHIAKSTGGTINLFEIDRNAGVLKLS----GDIDYEKV-KHYQIDVQARDPGRH 2745 Query: 776 ND-------VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDAD--VTD 825 +D V + + ++DVNDNAPV + + + P G RV A D D Sbjct: 2746 SDTCKSINSVTLSLQISDVNDNAPVFEQSSYQASVQFENAPNGAVVVRVSATDNDQGANG 2805 Query: 826 KLQYRIL--SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 ++ Y SG N +L + TG +T+ L+ K + + TD Sbjct: 2806 EITYSFSRSSGKNLDLFHIGPDTGEITVKGHLDYERAKQFELNIDATD 2853 Score = 372 bits (914), Expect = e-100 Identities = 261/804 (32%), Positives = 399/804 (49%), Gaps = 54/804 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I VLD ND++PVF + Y+AS+ E A GT + T+ A+D D G ++ Y I +TL Sbjct: 2432 ITVLDANDNAPVFTQKIYKASITENAVRGTVITTVSASDLDEGSYGKITYAI----TNTL 2487 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + V +F I+ +G + ++D EK Y + V+A+D ++D Sbjct: 2488 DD-------------VPVLFEINETNGEVRVIGTVDYEKARHYQIHVQASDDGG-LTDSC 2533 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 IH+ ++D NDN P F+ K Y S+ E+ +I + A+D D G+ I YA Sbjct: 2534 KIDVDIHITVLDANDNAPVFTHKIYKASITEN--AVRGTIITTVTASDLDEGSYGKITYA 2591 Query: 191 IIG--GNTQMQFSIDSLSGDVSL-VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 I GN M F I+ +G++ K + E + I A DGG P S T ++I + Sbjct: 2592 ITNSLGNFPMLFEINETNGEIQTREKMITLENPMEF-YSITAVDGGDPQLSGTIPIIITV 2650 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 D NDNAP + S+++ SV+EN P G + V+A DAD+G N ++ Y + K G ++L Sbjct: 2651 EDANDNAPICFMSVYKTSVAENSPKGTVLTTVKASDADQGQNGKVEYHIA-KSTGGTINL 2709 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG---DPPRSATA-TXXXXXXXXXXXX 363 ID +G + SG +D E YQ+ V A D G D +S + T Sbjct: 2710 -FEIDRNAGVLKLSGDIDYEKVKHYQIDVQARDPGRHSDTCKSINSVTLSLQISDVNDNA 2768 Query: 364 XXFMPGQYEVELA-EDEPPGTPVVTLTATDADE--DNRLHYEIT--GGNTRGRFSITSQN 418 F Y+ + E+ P G VV ++ATD D+ + + Y + G F I Sbjct: 2769 PVFEQSSYQASVQFENAPNGAVVVRVSATDNDQGANGEITYSFSRSSGKNLDLFHIGPDT 2828 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASV 478 G ITV LD+++ +++ L + ATD GG +D++ V I+ITD N+ PV ++ + Sbjct: 2829 GE--ITVKGHLDYERAKQFELNIDATDKGGLTDSSKVIIDITDVNDNPPVISLISFSNPI 2886 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 EDA T + +++ D D G N Q+ +S+++ + V Q F ++ T++L Sbjct: 2887 PEDAAPETVIAMLNVKDLDSGKNGQVKCYISADMPFK-VKSSAQNFY------SLITDQL 2939 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 LDRE +S Y +TVTA D G PS S + + + DVNDN PVF++Q YTA I+E+ G Sbjct: 2940 LDREKISEYNITVTATDEGSPSFSTNKTLTLKISDVNDNAPVFERQSYTAFIIENNSPGV 2999 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 SV V A D D G N RI Y LD E G+ V++ LDRE+ H L Sbjct: 3000 SVLSVKAHDRDSGNNARISYFLDLSGSEHGNDGSKYVEMVLQA--PLDRETQHEHKLTLT 3057 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 A DGG P ++ TV + + + D ND+ PVF + EN+P G + + A D D+G Sbjct: 3058 AFDGGNPQRTGTVRICVTVIDANDNAPVFSLPVYRVSLFENAPNGAVVVRVSATDNDQGA 3117 Query: 719 NAVVHYSIKGGDDSN----SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---AS 771 N + YS N +T + ++ L+T LD E +Y + + A S Sbjct: 3118 NGEITYSFSRSSGKNLDLFHIGADTGEITNFYSLITDQLLDREK-ISEYNITVTATDEGS 3176 Query: 772 PPLWNDVRVEILVTDVNDNAPVMK 795 P + + + ++DVNDNAPV + Sbjct: 3177 PSFSTNKTLTLKISDVNDNAPVFE 3200 Score = 365 bits (899), Expect = 7e-99 Identities = 261/802 (32%), Positives = 399/802 (49%), Gaps = 57/802 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I VLD ND++PVF Y+A+V E A T V T+ ATD D G N+++EY+I Sbjct: 2115 ITVLDANDNAPVFMQSVYKATVTENAPKDTIVSTVSATDADEGINSKIEYSIA------- 2167 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N +D V+ +F I+ +G + +D EK Y + V+A+D S + Sbjct: 2168 NRQD----------NVRQLFDINKDNGQVRVVGIIDFEKARNYEISVQASDHLS--GSKS 2215 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + + +D NDN P S+ Y S+ E+ V+ + A+DAD G+NS I ++ Sbjct: 2216 EPLTEVILEFLDANDNAPVCSQTVYKTSIAENSP--KGTVLTTVSASDADQGSNSRITFS 2273 Query: 191 IIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 I + F IDS G V L +DYEQ S IR+ DGG P S + + I + Sbjct: 2274 ISSTADKAADIFEIDSELGVVKLTGGIDYEQRHSLLTDIRSVDGGDPQLSGSIDIHITVL 2333 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 DVNDNAP F S+++ +V+EN P + V A DADEG+N+++ Y++ N+D Sbjct: 2334 DVNDNAPVFMQSVYKATVTENAPKDTIVSTVSATDADEGINSKIEYSI------ANIDNG 2387 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 ++ +S + G+ R K L A DGGDP S TA F Sbjct: 2388 QSVSIQSYYSRELGKGHR-VDHKNILYKNAIDGGDPQLSGTAQIHITVLDANDNAPVFTQ 2446 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITG--GNTRGRFSITSQNGRGLIT 424 Y+ + E+ GT + T++A+D DE + ++ Y IT + F I NG + Sbjct: 2447 KIYKASITENAVRGTVITTVSASDLDEGSYGKITYAITNTLDDVPVLFEINETNGE--VR 2504 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINI----TDANNYAPVFENAPYTASVFE 480 V +D+++ R Y + V A+D GG +D+ + ++I DAN+ APVF + Y AS+ E Sbjct: 2505 VIGTVDYEKARHYQIHVQASDDGGLTDSCKIDVDIHITVLDANDNAPVFTHKIYKASITE 2564 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKLL 539 +A GT + V+A+D D G +ITY++++ + N F IN G I T K++ Sbjct: 2565 NAVRGTIITTVTASDLDEGSYGKITYAITNSLGN-----FPMLFEINETNGEIQTREKMI 2619 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 E + ++TA DGG P LS T + I+V D NDN P+ +Y ++ E++ GT Sbjct: 2620 TLENPMEF-YSITAVDGGDPQLSGTIPIIITVEDANDNAPICFMSVYKTSVAENSPKGTV 2678 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREE-GSFVIDPASGVIRTNKALDRESVATHDLKAV 658 ++ V A+DAD G NG++ Y + F ID +GV++ + +D E V + + Sbjct: 2679 LTTVKASDADQGQNGKVEYHIAKSTGGTINLFEIDRNAGVLKLSGDIDYEKVKHYQIDVQ 2738 Query: 659 AIDGG----TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS-ENSPIGTTIGEIRAHD 713 A D G T ++V + ++I D+ND+ PVFE + EN+P G + + A D Sbjct: 2739 ARDPGRHSDTCKSINSVTLSLQISDVNDNAPVFEQSSYQASVQFENAPNGAVVVRVSATD 2798 Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP- 772 D+G N + YS N G D E+ LDYE K++EL I A Sbjct: 2799 NDQGANGEITYSFSRSSGKNLDLFHI--GPDTGEITVKGHLDYER-AKQFELNIDATDKG 2855 Query: 773 PLWNDVRVEILVTDVNDNAPVM 794 L + +V I +TDVNDN PV+ Sbjct: 2856 GLTDSSKVIIDITDVNDNPPVI 2877 Score = 363 bits (894), Expect = 3e-98 Identities = 269/862 (31%), Positives = 417/862 (48%), Gaps = 69/862 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND++PVF Y ASV E A GT + T+ ATD D G N + TL Sbjct: 1566 VTVLDVNDNAPVFNQTVYRASVTENAPKGTYITTVNATDADSGSNGHI----------TL 1615 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + D + +F ID +G + ++D EK R+ + VKATDQ L Sbjct: 1616 SFSDLKEQS-------RGIFNIDENTGLVSVLGNIDFEKDKRFEIRVKATDQGG-----L 1663 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDED------ISV-----TDNPVIAKIKATDA 179 +ST+ + + ++D NDN P + + + V ED I+V T I + A D Sbjct: 1664 TSTSKLIIEVVDVNDNAPVITLMSLSSPVSEDAPPGTTIAVLIENNTPGLSICSVTARDL 1723 Query: 180 DVGANSAIRY-----AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS 234 D NS + Y I G SI++ +G + V++ DYEQV+ + +++AQDGGS Sbjct: 1724 DWNQNSRVSYYLEDAHISGVPISSYVSINAENGVLHAVRSFDYEQVKQFSFIVKAQDGGS 1783 Query: 235 P--SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292 P S + + I + D NDNAP F S+++ +V+EN P + V A DADEG+N+++ Sbjct: 1784 PPLSSNKFIDIHITVLDANDNAPVFMQSVYKATVTENAPKDTIVSTVSATDADEGINSKI 1843 Query: 293 TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352 Y++ + + +V I+ +G V G +D E Y++ V A+D G + Sbjct: 1844 EYSIANME--DDVQRLFAINRDNGQVSVVGIIDFERARNYEIRVQASDQGG---LTDSYI 1898 Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI--TGGNT 408 F Y+ + E+ P GT V T++A+D D+ + + Y I T Sbjct: 1899 NIIVLDANDNAPVFSQTVYKTAVTENSPKGTIVTTVSASDLDQGVNGEITYSIRNTIDKV 1958 Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMV---QINITDANNY 465 R F I+ +G+ + + +D++Q R + + V A+D GG +D+ + I+I+D N+ Sbjct: 1959 RDIFEISETDGK--VRLIGLVDYEQARNFEIRVQASDHGGFTDSCKIIVDVIDISDVNDN 2016 Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525 APVFE + Y ASV A +G V V A D D G NA ++Y L + ++ A+ F Sbjct: 2017 APVFEQSSYQASVQRSADVGYLVTKVVAVDVDSGQNAWLSYKL-HKATDRAL------FE 2069 Query: 526 INPQTGAITT--NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583 + Q G I T K LDRE + L +TA DGG P LS + D+ I+V+D NDN PVF Q Sbjct: 2070 VGAQNGEIRTVRQKPLDREKQNEINLVLTAVDGGDPQLSGSIDIHITVLDANDNAPVFMQ 2129 Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFVIDPASGVIRTN 642 +Y A + E+A T VS V ATDAD G+N +I Y + + +D F I+ +G +R Sbjct: 2130 SVYKATVTENAPKDTIVSTVSATDADEGINSKIEYSIANRQDNVRQLFDINKDNGQVRVV 2189 Query: 643 KALDRESVATHDLKAVAID--GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700 +D E +++ A D G+ + T ++ ++ D ND+ PV I+ENS Sbjct: 2190 GIIDFEKARNYEISVQASDHLSGSKSEPLTEVI-LEFLDANDNAPVCSQTVYKTSIAENS 2248 Query: 701 PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760 P GT + + A D D+G N+ + +SI D + E +L +D + Sbjct: 2249 PKGTVLTTVSASDADQGSNSRITFSISSTADKAADIFEIDSELGVVKLTGGIDYEQRHSL 2308 Query: 761 KKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD 820 + P L + + I V DVNDNAPV ++ V A D Sbjct: 2309 LTDIRSVDGGDPQLSGSIDIHITVLDVNDNAPVFMQSVYKATVTENAPKDTIVSTVSATD 2368 Query: 821 AD--VTDKLQYRILSGNNANLI 840 AD + K++Y I + +N + Sbjct: 2369 ADEGINSKIEYSIANIDNGQSV 2390 Score = 361 bits (889), Expect = 1e-97 Identities = 272/813 (33%), Positives = 397/813 (48%), Gaps = 70/813 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND++P+ M Y+ SV E + GT + T+KA+D D G+N +VEY I T T+ Sbjct: 2648 ITVEDANDNAPICFMSVYKTSVAENSPKGTVLTTVKASDADQGQNGKVEYHIAKSTGGTI 2707 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N +F ID +G L +D EKV Y + V+A D SD Sbjct: 2708 N-----------------LFEIDRNAGVLKLSGDIDYEKVKHYQIDVQARDPGRH-SDTC 2749 Query: 131 SS--TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 S + T+ + I D NDN P F + +Y SV + + + V+ ++ ATD D GAN I Sbjct: 2750 KSINSVTLSLQISDVNDNAPVFEQSSYQASVQFE-NAPNGAVVVRVSATDNDQGANGEIT 2808 Query: 189 YAII--GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 Y+ G F I +G++++ LDYE+ + + L I A D G +++++++I+ Sbjct: 2809 YSFSRSSGKNLDLFHIGPDTGEITVKGHLDYERAKQFELNIDATDKGG--LTDSSKVIID 2866 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 I DVNDN P F + E+ I + D D G N ++ K Y + D Sbjct: 2867 ITDVNDNPPVISLISFSNPIPEDAAPETVIAMLNVKDLDSGKNGQV------KCYI-SAD 2919 Query: 307 LPITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 +P + + Y T LDRE ++Y + VTATD G P S T Sbjct: 2920 MPFKVKSSAQNFYSLITDQLLDREKISEYNITVTATDEGSPSFSTNKTLTLKISDVNDNA 2979 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEIT-GGNTRGRFSITSQNGR 420 F Y + E+ PG V+++ A D D N R+ Y + G+ G + + Sbjct: 2980 PVFERQSYTAFIIENNSPGVSVLSVKAHDRDSGNNARISYFLDLSGSEHG-----NDGSK 3034 Query: 421 GLITVAQ-PLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTAS 477 + V Q PLD + + + LT++A D G T V+I +T DAN+ APVF Y S Sbjct: 3035 YVEMVLQAPLDRETQHEHKLTLTAFDGGNPQRTGTVRICVTVIDANDNAPVFSLPVYRVS 3094 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT--- 534 +FE+AP G V+ VSATD+D G N +ITYS S H I TG IT Sbjct: 3095 LFENAPNGAVVVRVSATDNDQGANGEITYSFSRSSGKNLDLFH-----IGADTGEITNFY 3149 Query: 535 ---TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 T++LLDRE +S Y +TVTA D G PS S + + + DVNDN PVF++Q YTA IM Sbjct: 3150 SLITDQLLDREKISEYNITVTATDEGSPSFSTNKTLTLKISDVNDNAPVFERQSYTAFIM 3209 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDP---KDREEGSFV-IDPASGVIRTNKALDR 647 E+ G SV V A D D G N RI Y L+ +F+ ++ SG I ++ D Sbjct: 3210 ENNSPGVSVLSVKAHDRDSGNNARISYFLEDVVVNGVSASTFISVNAESGEILAARSFDY 3269 Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 E ++ A DGG+PP SS +++ + D ND+ P F I EN G+++ Sbjct: 3270 EQTKDFSIRVKAQDGGSPPLSSN--INVIVLDANDNAPAFSQSVYKASIPENFSKGSSVL 3327 Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNS--FSLETRQGSDKAELVTMVDLDYESPRKKYEL 765 ++ A D D G N V YS+ +S S F++++ G D VT LD E +Y + Sbjct: 3328 KVSAADGDTGSNGEVTYSLSQSSESFSGLFNIDSNTG-DITVNVTDDLLDREM-LSEYNI 3385 Query: 766 VIRA---ASPPLWNDVRVEILVTDVNDNAPVMK 795 + A SP + + + ++DVNDNAPV + Sbjct: 3386 TVTATDEGSPSFSTNKTLTLKISDVNDNAPVFE 3418 Score = 360 bits (886), Expect = 3e-97 Identities = 250/812 (30%), Positives = 396/812 (48%), Gaps = 68/812 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND++PVF Y ASV E A GT + T+ ATD D G + Y Sbjct: 1251 VTVLDANDNAPVFNQTVYRASVMENAPKGTYITTVNATDADAGSYGRITYNF-------- 1302 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +F ID +G + +D EK ++ + V+A DQ L Sbjct: 1303 ---------YKQKGAAAQLFNIDSNTGIISVVGEIDHEKDTKFELTVEARDQGG-----L 1348 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + ++ I +++ID NDN P + +++ +V ED + IA I DAD N + Sbjct: 1349 TDSSKITLDVIDVNDNAPVINAMSFSSTVSED--APPDTTIAIINVKDADTDDNGRVSCF 1406 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 I G + S +L SLV LD E++ Y + + A D G P ++ + + Sbjct: 1407 IEGSEDFVVKS--TLRNYYSLVTNVILDREKLSEYNITVVATDSGKPPLTSRKTFNLKVV 1464 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 DVNDNAP F ++ + EN G SI+R++A+D DE NA ++Y + + D + Sbjct: 1465 DVNDNAPVFRERVYNSYLPENNSPGVSILRIRAHDPDENQNARISYILEESD----LGTY 1520 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 ++++ SG V+ D E ++ V A DGG PP S+ T F Sbjct: 1521 VSVNAESGVVHAVRSFDYEQIKNIKVTVKAQDGGSPPLSSNVTIDVTVLDVNDNAPVFNQ 1580 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGN----TRGRFSITSQNGRGLIT 424 Y + E+ P GT + T+ ATDAD + H ++ + +RG F+I GL++ Sbjct: 1581 TVYRASVTENAPKGTYITTVNATDADSGSNGHITLSFSDLKEQSRGIFNI--DENTGLVS 1638 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 V +DF++++R+ + V ATD GG + T+ + I + D N+ APV ++ V EDAP Sbjct: 1639 VLGNIDFEKDKRFEIRVKATDQGGLTSTSKLIIEVVDVNDNAPVITLMSLSSPVSEDAPP 1698 Query: 485 GTTVLV-------------VSATDSDVGINAQITYSL-SSEISNEAVAHHDQQFVINPQT 530 GTT+ V V+A D D N++++Y L + IS ++ + IN + Sbjct: 1699 GTTIAVLIENNTPGLSICSVTARDLDWNQNSRVSYYLEDAHISGVPISSY---VSINAEN 1755 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT--TDVEISVVDVNDNEPVFKQQLYTA 588 G + + D E + + V A+DGG P LS D+ I+V+D NDN PVF Q +Y A Sbjct: 1756 GVLHAVRSFDYEQVKQFSFIVKAQDGGSPPLSSNKFIDIHITVLDANDNAPVFMQSVYKA 1815 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFVIDPASGVIRTNKALDR 647 + E+A T VS V ATDAD G+N +I Y + + +D + F I+ +G + +D Sbjct: 1816 TVTENAPKDTIVSTVSATDADEGINSKIEYSIANMEDDVQRLFAINRDNGQVSVVGIIDF 1875 Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 E ++++ A D G S ++I + D ND+ PVF ++ENSP GT + Sbjct: 1876 ERARNYEIRVQASDQGGLTDS---YINIIVLDANDNAPVFSQTVYKTAVTENSPKGTIVT 1932 Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 + A D D+G N + YSI+ D E + K L+ +V DYE R +E+ + Sbjct: 1933 TVSASDLDQGVNGEITYSIRNTIDKVRDIFEISETDGKVRLIGLV--DYEQAR-NFEIRV 1989 Query: 768 RAASPPLWND---VRVEIL-VTDVNDNAPVMK 795 +A+ + D + V+++ ++DVNDNAPV + Sbjct: 1990 QASDHGGFTDSCKIIVDVIDISDVNDNAPVFE 2021 Score = 353 bits (869), Expect = 3e-95 Identities = 262/897 (29%), Positives = 425/897 (47%), Gaps = 66/897 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 ++V+D ND++PV + ++V E A TT+ + D D N V IE Sbjct: 1356 LDVIDVNDNAPVINAMSFSSTVSEDAPPDTTIAIINVKDADTDDNGRVSCFIE------- 1408 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 ED V+ R +L+T LDREK++ Y + V ATD P L Sbjct: 1409 GSED---------FVVKSTLR---NYYSLVTNVILDREKLSEYNITVVATDSGKPP---L 1453 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +S T ++ ++D NDN P F E+ Y + E+ S I +I+A D D N+ I Y Sbjct: 1454 TSRKTFNLKVVDVNDNAPVFRERVYNSYLPENNS--PGVSILRIRAHDPDENQNARISYI 1511 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + + S+++ SG V V++ DYEQ+++ ++ ++AQDGGSP S+ + + + DV Sbjct: 1512 LEESDLGTYVSVNAESGVVHAVRSFDYEQIKNIKVTVKAQDGGSPPLSSNVTIDVTVLDV 1571 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD-KDYTGNVDLPI 309 NDNAP F ++++ SV+EN P G I V A DAD G N +T + +D K+ + + Sbjct: 1572 NDNAPVFNQTVYRASVTENAPKGTYITTVNATDADSGSNGHITLSFSDLKEQSRGI---F 1628 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA-----------TATXXXXXXX 358 ID +G V G +D E ++++ V ATD G ++ A Sbjct: 1629 NIDENTGLVSVLGNIDFEKDKRFEIRVKATDQGGLTSTSKLIIEVVDVNDNAPVITLMSL 1688 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHY-----EITGGNTRGR 411 PG L E+ PG + ++TA D D +++R+ Y I+G Sbjct: 1689 SSPVSEDAPPGTTIAVLIENNTPGLSICSVTARDLDWNQNSRVSYYLEDAHISGVPISSY 1748 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINIT--DANNYAP 467 SI ++N G++ + D++Q +++ V A D G S + I+IT DAN+ AP Sbjct: 1749 VSINAEN--GVLHAVRSFDYEQVKQFSFIVKAQDGGSPPLSSNKFIDIHITVLDANDNAP 1806 Query: 468 VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527 VF + Y A+V E+AP T V VSATD+D GIN++I YS+++ + ++ + F IN Sbjct: 1807 VFMQSVYKATVTENAPKDTIVSTVSATDADEGINSKIEYSIAN-MEDDV----QRLFAIN 1861 Query: 528 PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT 587 G ++ ++D E Y + V A D G L+D+ + I V+D NDN PVF Q +Y Sbjct: 1862 RDNGQVSVVGIIDFERARNYEIRVQASDQG--GLTDSY-INIIVLDANDNAPVFSQTVYK 1918 Query: 588 ANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFVIDPASGVIRTNKALD 646 + E++ GT V+ V A+D D G+NG I Y + + D+ F I G +R +D Sbjct: 1919 TAVTENSPKGTIVTTVSASDLDQGVNGEITYSIRNTIDKVRDIFEISETDGKVRLIGLVD 1978 Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVH-IKIEDINDSPPVFESDCLTFYISENSPIGTT 705 E +++ A D G S +IV I I D+ND+ PVFE + ++ +G Sbjct: 1979 YEQARNFEIRVQASDHGGFTDSCKIIVDVIDISDVNDNAPVFEQSSYQASVQRSADVGYL 2038 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765 + ++ A D D G NA + Y + D F + + G + +D + ++ Sbjct: 2039 VTKVVAVDVDSGQNAWLSYKLHKATDRALFEVGAQNGEIRTVRQKPLDREKQNEINLVLT 2098 Query: 766 VIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--V 823 + P L + + I V D NDNAPV ++ V A DAD + Sbjct: 2099 AVDGGDPQLSGSIDIHITVLDANDNAPVFMQSVYKATVTENAPKDTIVSTVSATDADEGI 2158 Query: 824 TDKLQYRILS--GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKA 878 K++Y I + N L +N+ G + + ++ + + V +D ++ K+ Sbjct: 2159 NSKIEYSIANRQDNVRQLFDINKDNGQVRVVGIIDFEKARNYEISVQASDHLSGSKS 2215 Score = 350 bits (861), Expect = 3e-94 Identities = 255/878 (29%), Positives = 424/878 (48%), Gaps = 53/878 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I VLD ND++PVF Y+ +V E + GT V T+ A+D D G N E+ Y+I +T+ Sbjct: 1900 IIVLDANDNAPVFSQTVYKTAVTENSPKGTIVTTVSASDLDQGVNGEITYSIR----NTI 1955 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + V+D+F I G + +D E+ + + V+A+D +D Sbjct: 1956 DK-------------VRDIFEISETDGKVRLIGLVDYEQARNFEIRVQASDHGG-FTDSC 2001 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + ++I D NDN P F + +Y SV V ++ K+ A D D G N+ + Y Sbjct: 2002 KIIVDV-IDISDVNDNAPVFEQSSYQASVQRSADV--GYLVTKVVAVDVDSGQNAWLSYK 2058 Query: 191 IIGGNTQMQFSIDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 + + F + + +G++ V K LD E+ LV+ A DGG P S + + I + Sbjct: 2059 LHKATDRALFEVGAQNGEIRTVRQKPLDREKQNEINLVLTAVDGGDPQLSGSIDIHITVL 2118 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D NDNAP F S+++ +V+EN P + V A DADEG+N+++ Y++ ++ NV Sbjct: 2119 DANDNAPVFMQSVYKATVTENAPKDTIVSTVSATDADEGINSKIEYSIANRQ--DNVRQL 2176 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 I+ +G V G +D E Y++ V A+D +S T Sbjct: 2177 FDINKDNGQVRVVGIIDFEKARNYEISVQASDHLSGSKSEPLTEVILEFLDANDNAPVCS 2236 Query: 369 GQ-YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITV 425 Y+ +AE+ P GT + T++A+DAD+ ++R+ + I+ + + G++ + Sbjct: 2237 QTVYKTSIAENSPKGTVLTTVSASDADQGSNSRITFSISSTADKAADIFEIDSELGVVKL 2296 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAP 483 +D++Q + + + D G + + I+IT D N+ APVF + Y A+V E+AP Sbjct: 2297 TGGIDYEQRHSLLTDIRSVDGGDPQLSGSIDIHITVLDVNDNAPVFMQSVYKATVTENAP 2356 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 T V VSATD+D GIN++I YS+++ + ++V+ + + + + +D + Sbjct: 2357 KDTIVSTVSATDADEGINSKIEYSIANIDNGQSVS------IQSYYSRELGKGHRVDHKN 2410 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 +L A DGG P LS T + I+V+D NDN PVF Q++Y A+I E+A+ GT ++ V Sbjct: 2411 ----ILYKNAIDGGDPQLSGTAQIHITVLDANDNAPVFTQKIYKASITENAVRGTVITTV 2466 Query: 604 GATDADVGLNGRIHYEL-DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 A+D D G G+I Y + + D F I+ +G +R +D E + + A D Sbjct: 2467 SASDLDEGSYGKITYAITNTLDDVPVLFEINETNGEVRVIGTVDYEKARHYQIHVQASDD 2526 Query: 663 G--TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 G T V +HI + D ND+ PVF I+EN+ GT I + A D DEG Sbjct: 2527 GGLTDSCKIDVDIHITVLDANDNAPVFTHKIYKASITENAVRGTIITTVTASDLDEGSYG 2586 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL-VIRAASPPLWNDVR 779 + Y+I + E + + + + + + E+P + Y + + P L + Sbjct: 2587 KITYAITNSLGNFPMLFEINETNGEIQTREKM-ITLENPMEFYSITAVDGGDPQLSGTIP 2645 Query: 780 VEILVTDVNDNAPVMKDFQIIF-NNYKDCFPVGP-FGRVPAYDAD--VTDKLQYRIL--S 833 + I V D NDNAP+ F ++ + + P G V A DAD K++Y I + Sbjct: 2646 IIITVEDANDNAPIC--FMSVYKTSVAENSPKGTVLTTVKASDADQGQNGKVEYHIAKST 2703 Query: 834 GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 G NL ++ G + LS ++ K ++V D Sbjct: 2704 GGTINLFEIDRNAGVLKLSGDIDYEKVKHYQIDVQARD 2741 Score = 345 bits (847), Expect = 1e-92 Identities = 261/888 (29%), Positives = 419/888 (47%), Gaps = 72/888 (8%) Query: 10 QINVLDCNDHSPVFEMQQY---EASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 +I + D ND+ PV Y + +V E A GT + + A D D G N+ V Y+ + Sbjct: 818 RIYITDMNDNPPVVLYPYYTVYKTNVAENAVKGTIITKVSAFDADQGYNSNVTYSFTHIA 877 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 DT + +F+I +G + +LD E V +Y + ++A D Sbjct: 878 EDTAH-----------------LFQISASTGDITLTGNLDYETVQQYELNLQAKDPWG-- 918 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 L+ + + ++++D NDN P S +++ + ED V+A I D D G N Sbjct: 919 ---LTGASKLVIDVVDVNDNSPVISMTSFSGKIQEDSPA--GTVVALISVQDLDSGKNGQ 973 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 +R A+ F+I + T LD E+V S+ L + A D GSPS + + Sbjct: 974 VRLAL---EQSSPFTIKPSPRKYYTLVTDAPLDREKVSSFNLTLVATDEGSPSLFSKITI 1030 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 +++ D+NDNAP F ++ V EN G S++ +QA D D G NA + Y + D D G Sbjct: 1031 SLDVTDINDNAPVFSQREYKAYVMENNSPGVSLLTLQASDPDAGQNARIAYYLIDSDVNG 1090 Query: 304 N-VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 + V +++ +G ++ D E ++++ V A DGG PP + AT Sbjct: 1091 SPVSSHFSVNADNGIIHAVRSFDYEQMKEFKIHVRAQDGGSPPLCSNATVVINVQDQNDN 1150 Query: 363 XXXFM-PGQYEVELAEDEPP-----GTPVVTLTATDADEDNR--LHYEITGGNTRGRFSI 414 + P Q + + P G V + A D D L Y++ R F + Sbjct: 1151 APQVLYPVQSGASVVAEIVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLHKATDRALFEV 1210 Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENA 472 +QNG + TV Q + L + A D G RS + ++ + + DAN+ APVF Sbjct: 1211 GAQNGE-IRTVRQE---SADDHDSLKLIAVDGGNPQRSGSVIIDVTVLDANDNAPVFNQT 1266 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 Y ASV E+AP GT + V+ATD+D G +ITY+ + A Q F I+ TG Sbjct: 1267 VYRASVMENAPKGTYITTVNATDADAGSYGRITYNFYKQKGAAA-----QLFNIDSNTGI 1321 Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592 I+ +D E + + LTV ARD G L+D++ + + V+DVNDN PV +++ + E Sbjct: 1322 ISVVGEIDHEKDTKFELTVEARDQG--GLTDSSKITLDVIDVNDNAPVINAMSFSSTVSE 1379 Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652 DA T+++ + DAD NGR+ ++ + + ++ TN LDRE ++ Sbjct: 1380 DAPPDTTIAIINVKDADTDDNGRVSCFIEGSEDFVVKSTLRNYYSLV-TNVILDREKLSE 1438 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 +++ VA D G PP +S ++K+ D+ND+ PVF Y+ EN+ G +I IRAH Sbjct: 1439 YNITVVATDSGKPPLTSRKTFNLKVVDVNDNAPVFRERVYNSYLPENNSPGVSILRIRAH 1498 Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA--- 769 DPDE NA + Y ++ D S+ G A + DYE K ++ ++A Sbjct: 1499 DPDENQNARISYILEESDLGTYVSVNAESGVVHA----VRSFDYEQ-IKNIKVTVKAQDG 1553 Query: 770 ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVGPF-GRVPAYDADVTDK- 826 SPPL ++V +++ V DVNDNAPV Q ++ + + P G + V A DAD Sbjct: 1554 GSPPLSSNVTIDVTVLDVNDNAPVFN--QTVYRASVTENAPKGTYITTVNATDADSGSNG 1611 Query: 827 ---LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 L + L + + ++E TG +++ ++ K + V TD Sbjct: 1612 HITLSFSDLKEQSRGIFNIDENTGLVSVLGNIDFEKDKRFEIRVKATD 1659 Score = 310 bits (762), Expect = 3e-82 Identities = 232/756 (30%), Positives = 368/756 (48%), Gaps = 46/756 (6%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 + +D +G + R LDREK Y + + A D +P L S+ T+ + + D NDN P Sbjct: 671 ILEVDSVTGEV--RIMLDREKCTHYNITITAVDAGTPP---LFSSKTVAITVTDINDNPP 725 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 F YTV E+ PVI KIKA DAD G N+ I Y++ ++ + SI++ +G+ Sbjct: 726 IFRHANYTVQFAEN-QPRGTPVI-KIKADDADGGQNARILYSL-SEDSAIYLSINTETGE 782 Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF---YTSLFQES 265 + ++ DYE + A+DGG PS ++T + I I D+NDN P Y ++++ + Sbjct: 783 IFTIRPFDYEASTHFYAQAMARDGGRPSFTSTCTIRIYITDMNDNPPVVLYPYYTVYKTN 842 Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTD-KDYTGNVDLPITIDPRSGWVYTSGQL 324 V+EN G I +V A+DAD+G N+ +TY+ T + T ++ I +G + +G L Sbjct: 843 VAENAVKGTIITKVSAFDADQGYNSNVTYSFTHIAEDTAHL---FQISASTGDITLTGNL 899 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 D ET +Y+L + A D ++ + ++ ED P GT Sbjct: 900 DYETVQQYELNLQAKDPWGLTGASKLVIDVVDVNDNSPVISMT--SFSGKIQEDSPAGTV 957 Query: 385 VVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ-PLDFKQERRYVLTVSA 443 V ++ D D + + F+I + V PLD ++ + LT+ A Sbjct: 958 VALISVQDLDSGKNGQVRLALEQS-SPFTIKPSPRKYYTLVTDAPLDREKVSSFNLTLVA 1016 Query: 444 TDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501 TD G S + +++TD N+ APVF Y A V E+ G ++L + A+D D G N Sbjct: 1017 TDEGSPSLFSKITISLDVTDINDNAPVFSQREYKAYVMENNSPGVSLLTLQASDPDAGQN 1076 Query: 502 AQITYSL-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560 A+I Y L S+++ V+ H F +N G I + D E M + + V A+DGG P Sbjct: 1077 ARIAYYLIDSDVNGSPVSSH---FSVNADNGIIHAVRSFDYEQMKEFKIHVRAQDGGSPP 1133 Query: 561 LSDTTDVEISVVDVNDNEP--VFKQQLYTANIME----DALVGTSVSQVGATDADVGLNG 614 L V I+V D NDN P ++ Q + + E A VG V++V A D D G N Sbjct: 1134 LCSNATVVINVQDQNDNAPQVLYPVQSGASVVAEIVPRSADVGYLVTKVVAVDVDSGQNA 1193 Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD-LKAVAIDGGTPPQSSTVIV 673 + Y+L K + F + +G IRT + +ES HD LK +A+DGG P +S +VI+ Sbjct: 1194 WLSYKLH-KATDRALFEVGAQNGEIRTVR---QESADDHDSLKLIAVDGGNPQRSGSVII 1249 Query: 674 HIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI--KGGDD 731 + + D ND+ PVF + EN+P GT I + A D D G + Y+ + G Sbjct: 1250 DVTVLDANDNAPVFNQTVYRASVMENAPKGTYITTVNATDADAGSYGRITYNFYKQKGAA 1309 Query: 732 SNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRAASPP-LWNDVRVEILVTDVND 789 + F++++ G ++++V ++D+E K +EL + A L + ++ + V DVND Sbjct: 1310 AQLFNIDSNTG-----IISVVGEIDHEKDTK-FELTVEARDQGGLTDSSKITLDVIDVND 1363 Query: 790 NAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD 825 NAPV+ +D P + DAD D Sbjct: 1364 NAPVINAMSFSSTVSEDAPPDTTIAIINVKDADTDD 1399 Score = 310 bits (761), Expect = 4e-82 Identities = 258/891 (28%), Positives = 398/891 (44%), Gaps = 81/891 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+ P+F Y E GT V+ +KA D D G+NA + Y++ Sbjct: 715 ITVTDINDNPPIFRHANYTVQFAENQPRGTPVIKIKADDADGGQNARILYSLS------- 767 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 ED+ I+ +G + T D E + A D P Sbjct: 768 --EDSAI-----------YLSINTETGEIFTIRPFDYEASTHFYAQAMARDGGRP---SF 811 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTV-SVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 +ST TI + I D NDN P YTV + + +I K+ A DAD G NS + Y Sbjct: 812 TSTCTIRIYITDMNDNPPVVLYPYYTVYKTNVAENAVKGTIITKVSAFDADQGYNSNVTY 871 Query: 190 AI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 + I +T F I + +GD++L LDYE V+ Y L ++A+D + ++L+I++ Sbjct: 872 SFTHIAEDTAHLFQISASTGDITLTGNLDYETVQQYELNLQAKDPW--GLTGASKLVIDV 929 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 DVNDN+P + F + E+ P G + + D D G N ++ + Sbjct: 930 VDVNDNSPVISMTSFSGKIQEDSPAGTVVALISVQDLDSGKNGQVRLALEQSS------- 982 Query: 308 PITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 P TI P Y T LDRE + + L + ATD G P + T Sbjct: 983 PFTIKPSPRKYYTLVTDAPLDREKVSSFNLTLVATDEGSPSLFSKITISLDVTDINDNAP 1042 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHY-----EITGGNTRGRFSITSQ 417 F +Y+ + E+ PG ++TL A+D D ++ R+ Y ++ G FS+ + Sbjct: 1043 VFSQREYKAYVMENNSPGVSLLTLQASDPDAGQNARIAYYLIDSDVNGSPVSSHFSVNAD 1102 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYA-----PVFE 470 N G+I + D++Q + + + V A D G A V IN+ D N+ A PV Sbjct: 1103 N--GIIHAVRSFDYEQMKEFKIHVRAQDGGSPPLCSNATVVINVQDQNDNAPQVLYPVQS 1160 Query: 471 NAPYTASVF-EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 A A + A +G V V A D D G NA ++Y L + ++ A+ F + Q Sbjct: 1161 GASVVAEIVPRSADVGYLVTKVVAVDVDSGQNAWLSYKL-HKATDRAL------FEVGAQ 1213 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589 G I T + + L + A DGG P S + ++++V+D NDN PVF Q +Y A+ Sbjct: 1214 NGEIRTVRQESADDHDS--LKLIAVDGGNPQRSGSVIIDVTVLDANDNAPVFNQTVYRAS 1271 Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFVIDPASGVIRTNKALDRE 648 +ME+A GT ++ V ATDAD G GRI Y K F ID +G+I +D E Sbjct: 1272 VMENAPKGTYITTVNATDADAGSYGRITYNFYKQKGAAAQLFNIDSNTGIISVVGEIDHE 1331 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 +L A D G SS + + + D+ND+ PV + + +SE++P TTI Sbjct: 1332 KDTKFELTVEARDQGGLTDSSKIT--LDVIDVNDNAPVINAMSFSSTVSEDAPPDTTIAI 1389 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768 I D D N V I+G +D F +++ + LVT V LD E +Y + + Sbjct: 1390 INVKDADTDDNGRVSCFIEGSED---FVVKSTL-RNYYSLVTNVILDREK-LSEYNITVV 1444 Query: 769 A---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY--KDCFPVGPFGRVPAYDADV 823 A PPL + + V DVNDNAPV + + ++N+Y ++ P R+ A+D D Sbjct: 1445 ATDSGKPPLTSRKTFNLKVVDVNDNAPVFR--ERVYNSYLPENNSPGVSILRIRAHDPDE 1502 Query: 824 TD--KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 ++ Y + + + +N +G + + K + V DG Sbjct: 1503 NQNARISYILEESDLGTYVSVNAESGVVHAVRSFDYEQIKNIKVTVKAQDG 1553 Score = 299 bits (734), Expect = 7e-79 Identities = 192/590 (32%), Positives = 301/590 (51%), Gaps = 26/590 (4%) Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS 164 LDRE+ T+++ A D +P S T IHV ++D NDN P FS+ Y VS+ E+ Sbjct: 1 LDREQQKEVTLILTAVDGGTPPR---SGTVAIHVTVLDANDNAPVFSQAVYKVSLPENSP 57 Query: 165 VTDNPVIAKIKATDADVGANSAIRYAI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222 V + V+ + ATDAD G N + Y + + FS++ +G++++ +DYE+ + Sbjct: 58 V--DTVVVTVSATDADEGQNGKVTYVFGHVSEEDKTLFSLNRNTGEITVTGAIDYEEKSA 115 Query: 223 YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY 282 Y L + A+D ++ + ++I++ D NDNAP + + E+ G + + Sbjct: 116 YELRVLAKDAAG--LTSYSMVIIDVTDTNDNAPVIISKSLNIPIPESALPGTEVGIINVQ 173 Query: 283 DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDG 341 D D N ++ ++ NV + ++ + + T+G+LDRE ++Y + +TATD Sbjct: 174 DRDSENNGQVRCSIQQ-----NVPFKLVPSIKNYYSLVTTGELDRELLSEYNITITATDE 228 Query: 342 GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRL 399 G PP S+T F Y+V L E+ P T VVT++ATDADE + + Sbjct: 229 GSPPLSSTKNIHLTVADVNDNPPVFQQAVYKVSLPENSPVDTVVVTVSATDADEGQNGEV 288 Query: 400 HYEITGGNTRGRFSITS-QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN 458 YE G + +I S G IT+ LD++ E + L + ATD G + V I+ Sbjct: 289 TYEF-GHISENDITIFSLDQNSGKITLIGSLDYEDEASFDLPIQATDGLGLVSYSTVVID 347 Query: 459 ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL-SSEISNEAV 517 ++D N+ PVF+ Y A V E+ G+++ VSATD D N + YSL SS+++ V Sbjct: 348 VSDVNDNPPVFQQQNYRAHVQENNKAGSSISSVSATDPDWRQNGTVVYSLLSSDVNGAPV 407 Query: 518 AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577 + IN TG I + D E M + + V ARD G P LS + ++V+D NDN Sbjct: 408 SSF---LSINGDTGVIHAVRSFDYEQMKSFKVLVLARDNGSPPLSSNVSIHVTVLDANDN 464 Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP-KDREEGSFVIDPAS 636 PVF Q +Y ++ E++ V T V V ATDAD G NG + YE + + F +D + Sbjct: 465 APVFSQAVYKVSLPENSPVDTVVVTVSATDADEGQNGEVTYEFGHIMEDYKHLFNLDRKT 524 Query: 637 GVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686 GVI +D E AT L+ +A DG S V+ I + D+ND+ P+ Sbjct: 525 GVISIKGPVDFEEEATFSLRIIAKDGSGLTSYSNVL--ISVSDVNDNSPI 572 Score = 284 bits (697), Expect = 2e-74 Identities = 218/790 (27%), Positives = 368/790 (46%), Gaps = 75/790 (9%) Query: 96 SGALLT-RASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKT 154 SG L+T R LDRE A + + + D P S TA+IH++++D NDN P S Sbjct: 586 SGRLITSRKPLDRESKADHFLTLSGVDGGRPSR---SGTASIHIHVLDANDNIPVGS--- 639 Query: 155 YTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI--IGGNTQMQFSIDSLSGDVSLV 212 V+ K+ ATD D G A+ Y+ + T+ +DS++G+V ++ Sbjct: 640 ---------------VLVKLNATDLDSGIYGAVSYSFSHVPDKTRGILEVDSVTGEVRIM 684 Query: 213 KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI 272 LD E+ Y + I A D G+P ++ + I + D+NDN P F + + +EN P Sbjct: 685 --LDREKCTHYNITITAVDAGTPPLFSSKTVAITVTDINDNPPIFRHANYTVQFAENQPR 742 Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332 G +++++A DAD G NA + Y++++ + ++I+ +G ++T D E + Sbjct: 743 GTPVIKIKADDADGGQNARILYSLSEDSA-----IYLSINTETGEIFTIRPFDYEASTHF 797 Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV---ELAEDEPPGTPVVTLT 389 A DGG P ++T T + Y V +AE+ GT + ++ Sbjct: 798 YAQAMARDGGRPSFTSTCTIRIYITDMNDNPPVVLYPYYTVYKTNVAENAVKGTIITKVS 857 Query: 390 ATDADE--DNRLHYEIT--GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445 A DAD+ ++ + Y T +T F I++ G IT+ LD++ ++Y L + A D Sbjct: 858 AFDADQGYNSNVTYSFTHIAEDTAHLFQISASTGD--ITLTGNLDYETVQQYELNLQAKD 915 Query: 446 SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505 G + + + I++ D N+ +PV ++ + ED+P GT V ++S D D G N Q+ Sbjct: 916 PWGLTGASKLVIDVVDVNDNSPVISMTSFSGKIQEDSPAGTVVALISVQDLDSGKNGQVR 975 Query: 506 YSLSSEISNEAVAHHDQQFVINPQTG---AITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 +L F I P + T+ LDRE +S + LT+ A D G PSL Sbjct: 976 LALEQS----------SPFTIKPSPRKYYTLVTDAPLDREKVSSFNLTLVATDEGSPSLF 1025 Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP 622 + + V D+NDN PVF Q+ Y A +ME+ G S+ + A+D D G N RI Y L Sbjct: 1026 SKITISLDVTDINDNAPVFSQREYKAYVMENNSPGVSLLTLQASDPDAGQNARIAYYLID 1085 Query: 623 KDRE----EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678 D F ++ +G+I ++ D E + + A DGG+PP S V I ++ Sbjct: 1086 SDVNGSPVSSHFSVNADNGIIHAVRSFDYEQMKEFKIHVRAQDGGSPPLCSNATVVINVQ 1145 Query: 679 DINDSPPVF------ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732 D ND+ P + + + ++ +G + ++ A D D G NA + Y + D Sbjct: 1146 DQNDNAPQVLYPVQSGASVVAEIVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLHKATDR 1205 Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP 792 F + + G + D D++S + + + +P V +++ V D NDNAP Sbjct: 1206 ALFEVGAQNGEIRTVRQESAD-DHDSLKL---IAVDGGNPQRSGSVIIDVTVLDANDNAP 1261 Query: 793 VMKDFQIIFN-NYKDCFPVGPF-GRVPAYDADVTD--KLQYRIL--SGNNANLILLNETT 846 V Q ++ + + P G + V A DAD ++ Y G A L ++ T Sbjct: 1262 VFN--QTVYRASVMENAPKGTYITTVNATDADAGSYGRITYNFYKQKGAAAQLFNIDSNT 1319 Query: 847 GSMTLSPQLN 856 G +++ +++ Sbjct: 1320 GIISVVGEID 1329 Score = 273 bits (670), Expect = 4e-71 Identities = 186/591 (31%), Positives = 291/591 (49%), Gaps = 29/591 (4%) Query: 215 LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY 274 LD EQ + L++ A DGG+P RS T + + + D NDNAP F ++++ S+ EN P+ Sbjct: 1 LDREQQKEVTLILTAVDGGTPPRSGTVAIHVTVLDANDNAPVFSQAVYKVSLPENSPVDT 60 Query: 275 SIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI-TIDPRSGWVYTSGQLDRETQAKYQ 333 +V V A DADEG N ++TY + D + +++ +G + +G +D E ++ Y+ Sbjct: 61 VVVTVSATDADEGQNGKVTYVF---GHVSEEDKTLFSLNRNTGEITVTGAIDYEEKSAYE 117 Query: 334 LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393 L V A D ++ + + + + E PGT V + D Sbjct: 118 LRVLAKDAAG--LTSYSMVIIDVTDTNDNAPVIISKSLNIPIPESALPGTEVGIINVQDR 175 Query: 394 DEDNRLHYEIT-GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--S 450 D +N + N + + +N L+T + LD + Y +T++ATD G S Sbjct: 176 DSENNGQVRCSIQQNVPFKLVPSIKNYYSLVTTGE-LDRELLSEYNITITATDEGSPPLS 234 Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510 T + + + D N+ PVF+ A Y S+ E++P+ T V+ VSATD+D G N ++TY Sbjct: 235 STKNIHLTVADVNDNPPVFQQAVYKVSLPENSPVDTVVVTVSATDADEGQNGEVTYEFGH 294 Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG-GVPSLSDTTDVEI 569 N+ F ++ +G IT LD E + + L + A DG G+ S S V I Sbjct: 295 ISENDITI-----FSLDQNSGKITLIGSLDYEDEASFDLPIQATDGLGLVSYST---VVI 346 Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL---DPKDRE 626 V DVNDN PVF+QQ Y A++ E+ G+S+S V ATD D NG + Y L D Sbjct: 347 DVSDVNDNPPVFQQQNYRAHVQENNKAGSSISSVSATDPDWRQNGTVVYSLLSSDVNGAP 406 Query: 627 EGSFV-IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685 SF+ I+ +GVI ++ D E + + + +A D G+PP SS V +H+ + D ND+ P Sbjct: 407 VSSFLSINGDTGVIHAVRSFDYEQMKSFKVLVLARDNGSPPLSSNVSIHVTVLDANDNAP 466 Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG--GDDSNSFSLETRQGS 743 VF + ENSP+ T + + A D DEG N V Y D + F+L+ + G Sbjct: 467 VFSQAVYKVSLPENSPVDTVVVTVSATDADEGQNGEVTYEFGHIMEDYKHLFNLDRKTG- 525 Query: 744 DKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVM 794 + +D+E +I L + V I V+DVNDN+P++ Sbjct: 526 ---VISIKGPVDFEEEATFSLRIIAKDGSGLTSYSNVLISVSDVNDNSPII 573 Score = 242 bits (593), Expect = 8e-62 Identities = 177/580 (30%), Positives = 287/580 (49%), Gaps = 48/580 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND++PVF Y+ S+ E + T V+T+ ATD D G+N +V Y V Sbjct: 31 VTVLDANDNAPVFSQAVYKVSLPENSPVDTVVVTVSATDADEGQNGKVTYVFGHV----- 85 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + ED + +F ++ +G + ++D E+ + Y + V A D A L Sbjct: 86 SEED------------KTLFSLNRNTGEITVTGAIDYEEKSAYELRVLAKDAAG-----L 128 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +S + + +++ D NDN P K+ + + E S + I D D N +R + Sbjct: 129 TSYSMVIIDVTDTNDNAPVIISKSLNIPIPE--SALPGTEVGIINVQDRDSENNGQVRCS 186 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 I N + + S+ SLV T LD E + Y + I A D GSP S+T + + + Sbjct: 187 -IQQNVPFKL-VPSIKNYYSLVTTGELDRELLSEYNITITATDEGSPPLSSTKNIHLTVA 244 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 DVNDN P F ++++ S+ EN P+ +V V A DADEG N E+TY + + D+ Sbjct: 245 DVNDNPPVFQQAVYKVSLPENSPVDTVVVTVSATDADEGQNGEVTY---EFGHISENDIT 301 Query: 309 I-TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 I ++D SG + G LD E +A + L + ATDG + +T F Sbjct: 302 IFSLDQNSGKITLIGSLDYEDEASFDLPIQATDG--LGLVSYSTVVIDVSDVNDNPPVFQ 359 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGR--FSITSQNG-RGL 422 Y + E+ G+ + +++ATD D ++ + Y + + G S S NG G+ Sbjct: 360 QQNYRAHVQENNKAGSSISSVSATDPDWRQNGTVVYSLLSSDVNGAPVSSFLSINGDTGV 419 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFE 480 I + D++Q + + + V A D+G ++ V I++T DAN+ APVF A Y S+ E Sbjct: 420 IHAVRSFDYEQMKSFKVLVLARDNGSPPLSSNVSIHVTVLDANDNAPVFSQAVYKVSLPE 479 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 ++P+ T V+ VSATD+D G N ++TY + + F ++ +TG I+ +D Sbjct: 480 NSPVDTVVVTVSATDADEGQNGEVTYEF-----GHIMEDYKHLFNLDRKTGVISIKGPVD 534 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580 E + + L + A+DG L+ ++V ISV DVNDN P+ Sbjct: 535 FEEEATFSLRIIAKDGS--GLTSYSNVLISVSDVNDNSPI 572 Score = 194 bits (472), Expect = 4e-47 Identities = 132/372 (35%), Positives = 190/372 (51%), Gaps = 18/372 (4%) Query: 429 LDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD +Q++ L ++A D G RS T + + + DAN+ APVF A Y S+ E++P+ T Sbjct: 1 LDREQQKEVTLILTAVDGGTPPRSGTVAIHVTVLDANDNAPVFSQAVYKVSLPENSPVDT 60 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 V+ VSATD+D G N ++TY + +S E F +N TG IT +D E S Sbjct: 61 VVVTVSATDADEGQNGKVTY-VFGHVSEE----DKTLFSLNRNTGEITVTGAIDYEEKSA 115 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y L V A+D L+ + V I V D NDN PV + I E AL GT V + Sbjct: 116 YELRVLAKDAA--GLTSYSMVIIDVTDTNDNAPVIISKSLNIPIPESALPGTEVGIINVQ 173 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D D NG++ + + I ++ T + LDRE ++ +++ A D G+PP Sbjct: 174 DRDSENNGQVRCSIQQNVPFKLVPSIKNYYSLVTTGE-LDRELLSEYNITITATDEGSPP 232 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 SST +H+ + D+ND+PPVF+ + ENSP+ T + + A D DEG N V Y Sbjct: 233 LSSTKNIHLTVADVNDNPPVFQQAVYKVSLPENSPVDTVVVTVSATDADEGQNGEVTYEF 292 Query: 727 K--GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP-PLWNDVRVEIL 783 +D FSL+ Q S K L+ LDYE ++L I+A L + V I Sbjct: 293 GHISENDITIFSLD--QNSGKITLIG--SLDYED-EASFDLPIQATDGLGLVSYSTVVID 347 Query: 784 VTDVNDNAPVMK 795 V+DVNDN PV + Sbjct: 348 VSDVNDNPPVFQ 359 Score = 175 bits (427), Expect = 1e-41 Identities = 137/417 (32%), Positives = 216/417 (51%), Gaps = 44/417 (10%) Query: 386 VTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445 V ++ +D ++++ + +T T G F +GR LIT +PLD + + + LT+S D Sbjct: 559 VLISVSDVNDNSPIIIPLT--ETPGSFM---PSGR-LITSRKPLDRESKADHFLTLSGVD 612 Query: 446 SG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503 G RS TA + I++ DAN ++ P+G+ ++ ++ATD D GI Sbjct: 613 GGRPSRSGTASIHIHVLDAN----------------DNIPVGSVLVKLNATDLDSGIYGA 656 Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD 563 ++YS S + ++ + ++ TG + +LDRE + Y +T+TA D G P L Sbjct: 657 VSYSF-SHVPDKTRGILE----VDSVTGEVRI--MLDREKCTHYNITITAVDAGTPPLFS 709 Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK 623 + V I+V D+NDN P+F+ YT E+ GT V ++ A DAD G N RI Y L Sbjct: 710 SKTVAITVTDINDNPPIFRHANYTVQFAENQPRGTPVIKIKADDADGGQNARILYSLSED 769 Query: 624 DREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS 683 S I+ +G I T + D E+ +A+A DGG P +ST + I I D+ND+ Sbjct: 770 SAIYLS--INTETGEIFTIRPFDYEASTHFYAQAMARDGGRPSFTSTCTIRIYITDMNDN 827 Query: 684 PPVFESDCLTFY---ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK--GGDDSNSFSLE 738 PPV T Y ++EN+ GT I ++ A D D+G N+ V YS D ++ F + Sbjct: 828 PPVVLYPYYTVYKTNVAENAVKGTIITKVSAFDADQGYNSNVTYSFTHIAEDTAHLFQIS 887 Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRAASP-PLWNDVRVEILVTDVNDNAPVM 794 G ++ +LDYE+ ++YEL ++A P L ++ I V DVNDN+PV+ Sbjct: 888 ASTG----DITLTGNLDYETV-QQYELNLQAKDPWGLTGASKLVIDVVDVNDNSPVI 939 Score = 151 bits (365), Expect = 4e-34 Identities = 107/339 (31%), Positives = 166/339 (48%), Gaps = 33/339 (9%) Query: 528 PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT 587 P IT+ K LDRE+ + + LT++ DGG PS S T + I V+D NDN P Sbjct: 585 PSGRLITSRKPLDRESKADHFLTLSGVDGGRPSRSGTASIHIHVLDANDNIP-------- 636 Query: 588 ANIMEDALVGTSVSQVGATDADVGLNGRIHYELD-PKDREEGSFVIDPASGVIRTNKALD 646 VG+ + ++ ATD D G+ G + Y D+ G +D +G +R LD Sbjct: 637 --------VGSVLVKLNATDLDSGIYGAVSYSFSHVPDKTRGILEVDSVTGEVRI--MLD 686 Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706 RE +++ A+D GTPP S+ V I + DIND+PP+F T +EN P GT + Sbjct: 687 REKCTHYNITITAVDAGTPPLFSSKTVAITVTDINDNPPIFRHANYTVQFAENQPRGTPV 746 Query: 707 GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV 766 +I+A D D G NA + YS+ D + S+ T G E+ T+ DYE+ Y Sbjct: 747 IKIKADDADGGQNARILYSL-SEDSAIYLSINTETG----EIFTIRPFDYEASTHFYAQA 801 Query: 767 IR--AASPPLWNDVRVEILVTDVNDNAPVM--KDFQIIFNNYKDCFPVGP-FGRVPAYDA 821 + P + + I +TD+NDN PV+ + + N + G +V A+DA Sbjct: 802 MARDGGRPSFTSTCTIRIYITDMNDNPPVVLYPYYTVYKTNVAENAVKGTIITKVSAFDA 861 Query: 822 D--VTDKLQYRI--LSGNNANLILLNETTGSMTLSPQLN 856 D + Y ++ + A+L ++ +TG +TL+ L+ Sbjct: 862 DQGYNSNVTYSFTHIAEDTAHLFQISASTGDITLTGNLD 900 Score = 142 bits (345), Expect = 9e-32 Identities = 112/345 (32%), Positives = 167/345 (48%), Gaps = 19/345 (5%) Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 LDRE L +TA DGG P S T + ++V+D NDN PVF Q +Y ++ E++ V T Sbjct: 1 LDREQQKEVTLILTAVDGGTPPRSGTVAIHVTVLDANDNAPVFSQAVYKVSLPENSPVDT 60 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKALDRESVATHDLKA 657 V V ATDAD G NG++ Y E+ + F ++ +G I A+D E + ++L+ Sbjct: 61 VVVTVSATDADEGQNGKVTYVFGHVSEEDKTLFSLNRNTGEITVTGAIDYEEKSAYELRV 120 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 +A D S VI I + D ND+ PV S L I E++ GT +G I D D Sbjct: 121 LAKDAAGLTSYSMVI--IDVTDTNDNAPVIISKSLNIPIPESALPGTEVGIINVQDRDSE 178 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPL 774 N V SI+ + F L + LVT +LD E +Y + I A SPPL Sbjct: 179 NNGQVRCSIQ---QNVPFKL-VPSIKNYYSLVTTGELDREL-LSEYNITITATDEGSPPL 233 Query: 775 WNDVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVGP-FGRVPAYDAD--VTDKLQYR 830 + + + V DVNDN PV + Q ++ + + PV V A DAD ++ Y Sbjct: 234 SSTKNIHLTVADVNDNPPVFQ--QAVYKVSLPENSPVDTVVVTVSATDADEGQNGEVTYE 291 Query: 831 I--LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGV 873 +S N+ + L++ +G +TL L+ + + TDG+ Sbjct: 292 FGHISENDITIFSLDQNSGKITLIGSLDYEDEASFDLPIQATDGL 336 Score = 137 bits (331), Expect = 5e-30 Identities = 86/263 (32%), Positives = 133/263 (50%), Gaps = 30/263 (11%) Query: 2 SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 S P + + VLD ND++P F Y+AS+ E S G++VL + A D D G N EV Y+ Sbjct: 3286 SPPLSSNINVIVLDANDNAPAFSQSVYKASIPENFSKGSSVLKVSAADGDTGSNGEVTYS 3345 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS---LDREKVARYTVLVK 118 + +F ID +G + + LDRE ++ Y + V Sbjct: 3346 LS-----------------QSSESFSGLFNIDSNTGDITVNVTDDLLDREMLSEYNITVT 3388 Query: 119 ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178 ATD+ SP S+ T+ + I D NDN P F ++YT + E+ S + +KA D Sbjct: 3389 ATDEGSP---SFSTNKTLTLKISDVNDNAPVFERQSYTAFIMENNS--PGVSVLSVKAHD 3443 Query: 179 ADVGANSAIRY----AIIGGNTQMQF-SIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233 D G N+ I Y ++ G + F S+ + SG++ ++ DYEQ + + + ++AQDGG Sbjct: 3444 RDSGNNARISYFLEDVVVNGVSASTFISVHAESGEILAARSFDYEQTKDFSIRVKAQDGG 3503 Query: 234 SPSRSNTTQLLINIRDVNDNAPR 256 SP S+ + I I+D NDNAP+ Sbjct: 3504 SPPLSSNVSVKILIQDQNDNAPQ 3526 Score = 132 bits (318), Expect = 2e-28 Identities = 96/291 (32%), Positives = 150/291 (51%), Gaps = 27/291 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+V D ND+ PVF+ Q Y A V+E +G+++ ++ ATD D +N V Y+ L+++D Sbjct: 346 IDVSDVNDNPPVFQQQNYRAHVQENNKAGSSISSVSATDPDWRQNGTVVYS--LLSSDV- 402 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 V I+G +G + S D E++ + VLV A D SP L Sbjct: 403 -----------NGAPVSSFLSINGDTGVIHAVRSFDYEQMKSFKVLVLARDNGSP---PL 448 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SS +IHV ++D NDN P FS+ Y VS+ E+ V + V+ + ATDAD G N + Y Sbjct: 449 SSNVSIHVTVLDANDNAPVFSQAVYKVSLPENSPV--DTVVVTVSATDADEGQNGEVTYE 506 Query: 191 I--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG-GSPSRSNTTQLLINI 247 I + + F++D +G +S+ +D+E+ ++ L I A+DG G S SN +LI++ Sbjct: 507 FGHIMEDYKHLFNLDRKTGVISIKGPVDFEEEATFSLRIIAKDGSGLTSYSN---VLISV 563 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 DVNDN+P E+ +P G I + D + + LT + D Sbjct: 564 SDVNDNSPIIIP--LTETPGSFMPSGRLITSRKPLDRESKADHFLTLSGVD 612 Score = 86.6 bits (205), Expect = 9e-15 Identities = 82/268 (30%), Positives = 122/268 (45%), Gaps = 29/268 (10%) Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES 649 I +D TS S V + +DV N I + P GSF+ P+ +I + K LDRES Sbjct: 546 IAKDGSGLTSYSNVLISVSDVNDNSPI---IIPLTETPGSFM--PSGRLITSRKPLDRES 600 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 A H L +DGG P +S T +HI + D ND N P+G+ + ++ Sbjct: 601 KADHFLTLSGVDGGRPSRSGTASIHIHVLDAND----------------NIPVGSVLVKL 644 Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 A D D G V YS D LE S E+ M+D + + + A Sbjct: 645 NATDLDSGIYGAVSYSFSHVPDKTRGILEV--DSVTGEVRIMLDREKCTHYNITITAVDA 702 Query: 770 ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDK 826 +PPL++ V I VTD+NDN P+ + + + P G P ++ A DAD + Sbjct: 703 GTPPLFSSKTVAITVTDINDNPPIFRHANYTV-QFAENQPRGTPVIKIKADDADGGQNAR 761 Query: 827 LQYRILSGNNANLILLNETTGSM-TLSP 853 + Y LS ++A + +N TG + T+ P Sbjct: 762 ILYS-LSEDSAIYLSINTETGEIFTIRP 788 >UniRef50_UPI00006A0F38 Cluster: dachsous 2 isoform 1; n=1; Xenopus tropicalis|Rep: dachsous 2 isoform 1 - Xenopus tropicalis Length = 3555 Score = 378 bits (931), Expect = e-103 Identities = 269/870 (30%), Positives = 421/870 (48%), Gaps = 76/870 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I V D ND+ P+F + Y S+ E +TVL + A D+D G N+++ Y+ + Sbjct: 2679 RITVTDMNDNFPIFGQEVYTVSINENIPLNSTVLCVSANDKDQGINSQITYSFSATSKQA 2738 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 F I+ +G + T+ +LD EK Y + V+A Q Sbjct: 2739 SRS-----------------FSINSETGEIKTKENLDFEKTKNYEISVQAKIQ----KHH 2777 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + S I + + D NDN+P F+++ Y V++ E+I + + + ++ A+D D G N+ I Y Sbjct: 2778 ILSLINIQITVTDFNDNFPVFTQEVYKVNIHENIPI--HSTVLQVNASDKDEGINAQITY 2835 Query: 190 AI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 + N F+I+ SG+++ +D+E+ + Y + ++AQDGGS ++ ++LI I Sbjct: 2836 SFGTTATNVLRIFAINPKSGEITTKGNVDFEETKYYDISVQAQDGGS--LASHAKVLIQI 2893 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 D NDNAP + VSE+ P G + ++A+D D G N E+ D + G + Sbjct: 2894 LDENDNAPEISVTSITTPVSEDSPTGTVVALIKAHDLDSGENGEV-----DCEIVGVI-- 2946 Query: 308 PITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 P + SG Y T+ LDRE +Y L + TD G P S+ T Sbjct: 2947 PFKLLSSSGNFYKIITTSTLDREKTPRYNLTIHTTDKGSPTLSSLKTIRLDILDINDNPP 3006 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTR-----GRFSITSQ 417 F Y + E+ PG + ++ A D D E+ ++ Y I NT SI S Sbjct: 3007 KFEKSNYVAYVTENNQPGASIYSIQAIDEDTEENGKVVYSIFTNNTEKFPSFSYISINSV 3066 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYT 475 G + LD + + + L ++A+D G ++ T +++I +TD N+ PVF Y Sbjct: 3067 TGGEKKSTDTSLDRETQSNHELILTASDGGNPVQTGTTLIKITVTDFNDNFPVFTQEVYK 3126 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 ++ E+ PI +TVL V+A+D D GINAQ+TYS S+ +N H + F INP G ITT Sbjct: 3127 VNIHENIPINSTVLRVNASDKDAGINAQVTYSFSTSANN---VH--RIFSINPNNGEITT 3181 Query: 536 N-KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 LDRE Y +T+ A D G P LS + + V D+NDN P F++ Y A + E+ Sbjct: 3182 KASTLDREKTPHYNITIQATDKGSPPLSSKKTIRLDVSDINDNPPKFEKSNYVAYVTENN 3241 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS---FVIDPASGVIRTNKALDRESVA 651 G+S+ + A D D NG++ Y + E S I+P +GVI ++ D E Sbjct: 3242 QPGSSIFSIKAIDKDTEENGKVVYSISNNTVEFSSVSYISINPVTGVIYALQSFDYEQDR 3301 Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711 ++ +A D G+P +S+ IV+I + D ND+ PVF + I EN PI +T+ + A Sbjct: 3302 EFLIQIMAKDSGSPSLNSSAIVNITVTDFNDNFPVFTQEVYKVNIHENIPINSTVLHVNA 3361 Query: 712 HDPDEGPNAVVHYSIK--GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 D DEG NA + YS + F + + G E+ LD E Y + I+A Sbjct: 3362 SDKDEGINAQITYSFSTTSANVLRMFYINPQNG----EIKIKGTLDRERS-SHYNITIQA 3416 Query: 770 A---SPPL--WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVT 824 SPPL W + +E+L D+NDN+PV + I ++ P + A D D Sbjct: 3417 TDKGSPPLSSWKTIALEVL--DINDNSPVFEKSTYIAYVPENNQPGASIYSIQAIDKDTE 3474 Query: 825 D--KLQYRILSGNNANL-----ILLNETTG 847 + KL Y I++ N L I +N TG Sbjct: 3475 ENGKLFYSIITSNTEELSSTSYISINPVTG 3504 Score = 374 bits (920), Expect = e-101 Identities = 261/810 (32%), Positives = 403/810 (49%), Gaps = 59/810 (7%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 I+ QI V D ND+ PVF + Y+ ++ E +TVL + A+D+D G NA++ Y+ Sbjct: 2782 INIQITVTDFNDNFPVFTQEVYKVNIHENIPIHSTVLQVNASDKDEGINAQITYSFGTTA 2841 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 + L +F I+ +SG + T+ ++D E+ Y + V+A D S Sbjct: 2842 TNVLR-----------------IFAINPKSGEITTKGNVDFEETKYYDISVQAQDGGS-- 2882 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 L+S A + + I+D+NDN P+ S + T V ED S T V+A IKA D D G N Sbjct: 2883 ---LASHAKVLIQILDENDNAPEISVTSITTPVSED-SPTGT-VVALIKAHDLDSGENGE 2937 Query: 187 IRYAIIGGNTQMQFSIDSLSGD---VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 + I+G + F + S SG+ + TLD E+ Y L I D GSP+ S+ + Sbjct: 2938 VDCEIVG---VIPFKLLSSSGNFYKIITTSTLDREKTPRYNLTIHTTDKGSPTLSSLKTI 2994 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 ++I D+NDN P+F S + V+EN G SI +QA D D N ++ Y++ +T Sbjct: 2995 RLDILDINDNPPKFEKSNYVAYVTENNQPGASIYSIQAIDEDTEENGKVVYSI----FTN 3050 Query: 304 NVD-LP----ITIDPRSGWVY--TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 N + P I+I+ +G T LDRETQ+ ++L++TA+DGG+P ++ T Sbjct: 3051 NTEKFPSFSYISINSVTGGEKKSTDTSLDRETQSNHELILTASDGGNPVQTGTTLIKITV 3110 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH----YEITGGNTRGRF 412 F Y+V + E+ P + V+ + A+D D + + N F Sbjct: 3111 TDFNDNFPVFTQEVYKVNIHENIPINSTVLRVNASDKDAGINAQVTYSFSTSANNVHRIF 3170 Query: 413 SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFE 470 SI NG + T A LD ++ Y +T+ ATD G S ++++++D N+ P FE Sbjct: 3171 SINPNNGE-ITTKASTLDREKTPHYNITIQATDKGSPPLSSKKTIRLDVSDINDNPPKFE 3229 Query: 471 NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV-INPQ 529 + Y A V E+ G+++ + A D D N ++ YS ISN V ++ INP Sbjct: 3230 KSNYVAYVTENNQPGSSIFSIKAIDKDTEENGKVVYS----ISNNTVEFSSVSYISINPV 3285 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589 TG I + D E +L+ + A+D G PSL+ + V I+V D NDN PVF Q++Y N Sbjct: 3286 TGVIYALQSFDYEQDREFLIQIMAKDSGSPSLNSSAIVNITVTDFNDNFPVFTQEVYKVN 3345 Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE-GSFVIDPASGVIRTNKALDRE 648 I E+ + ++V V A+D D G+N +I Y F I+P +G I+ LDRE Sbjct: 3346 IHENIPINSTVLHVNASDKDEGINAQITYSFSTTSANVLRMFYINPQNGEIKIKGTLDRE 3405 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 + +++ A D G+PP SS + +++ DIND+ PVFE Y+ EN+ G +I Sbjct: 3406 RSSHYNITIQATDKGSPPLSSWKTIALEVLDINDNSPVFEKSTYIAYVPENNQPGASIYS 3465 Query: 709 IRAHDPDEGPNAVVHYS-IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 I+A D D N + YS I + S + + DYE R ++E+ I Sbjct: 3466 IQAIDKDTEENGKLFYSIITSNTEELSSTSYISINPVTGVIYAQRSFDYEQDR-EFEIQI 3524 Query: 768 RA---ASPPLWNDVRVEILVTDVNDNAPVM 794 A SPPL + V I V D NDN+P + Sbjct: 3525 IAKDNGSPPLNSSTIVRICVVDQNDNSPTV 3554 Score = 359 bits (884), Expect = 5e-97 Identities = 263/879 (29%), Positives = 413/879 (46%), Gaps = 49/879 (5%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I +LD ND+ P + V E ++ GT V+ L A D+D G NA++ Y+ + Sbjct: 2571 IQILDENDNPPEVSLTSITNPVSEESAPGT-VVALIANDKDEGINAQITYSFSATSKQAS 2629 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F I+ SG + T+ ++D EK Y + V+A S Sbjct: 2630 RS-----------------FAINAISGEIKTKENIDFEKTKYYEISVQARISFDGGSPMQ 2672 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + TA I + + D NDN+P F ++ YTVS++E+I + N + + A D D G NS I Y+ Sbjct: 2673 TGTALIRITVTDMNDNFPIFGQEVYTVSINENIPL--NSTVLCVSANDKDQGINSQITYS 2730 Query: 191 IIGGNTQ--MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 + Q FSI+S +G++ + LD+E+ ++Y + ++A+ S + I + Sbjct: 2731 FSATSKQASRSFSINSETGEIKTKENLDFEKTKNYEISVQAKIQKHHILS-LINIQITVT 2789 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D NDN P F +++ ++ EN+PI ++++V A D DEG+NA++TY+ NV Sbjct: 2790 DFNDNFPVFTQEVYKVNIHENIPIHSTVLQVNASDKDEGINAQITYSFGTT--ATNVLRI 2847 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 I+P+SG + T G +D E Y + V A DGG ++ A Sbjct: 2848 FAINPKSGEITTKGNVDFEETKYYDISVQAQDGGS--LASHAKVLIQILDENDNAPEISV 2905 Query: 369 GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGL-ITV 425 ++ED P GT V + A D D E+ + EI G F + S +G I Sbjct: 2906 TSITTPVSEDSPTGTVVALIKAHDLDSGENGEVDCEIVGVIP---FKLLSSSGNFYKIIT 2962 Query: 426 AQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 LD ++ RY LT+ TD G S ++++I D N+ P FE + Y A V E+ Sbjct: 2963 TSTLDREKTPRYNLTIHTTDKGSPTLSSLKTIRLDILDINDNPPKFEKSNYVAYVTENNQ 3022 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA--ITTNKLLDR 541 G ++ + A D D N ++ YS+ + +N IN TG +T+ LDR Sbjct: 3023 PGASIYSIQAIDEDTEENGKVVYSIFT--NNTEKFPSFSYISINSVTGGEKKSTDTSLDR 3080 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 ET S + L +TA DGG P + TT ++I+V D NDN PVF Q++Y NI E+ + ++V Sbjct: 3081 ETQSNHELILTASDGGNPVQTGTTLIKITVTDFNDNFPVFTQEVYKVNIHENIPINSTVL 3140 Query: 602 QVGATDADVGLNGRIHYELDPK-DREEGSFVIDPASGVIRTN-KALDRESVATHDLKAVA 659 +V A+D D G+N ++ Y + F I+P +G I T LDRE +++ A Sbjct: 3141 RVNASDKDAGINAQVTYSFSTSANNVHRIFSINPNNGEITTKASTLDREKTPHYNITIQA 3200 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 D G+PP SS + + + DIND+PP FE Y++EN+ G++I I+A D D N Sbjct: 3201 TDKGSPPLSSKKTIRLDVSDINDNPPKFEKSNYVAYVTENNQPGSSIFSIKAIDKDTEEN 3260 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR--AASPPLWND 777 V YSI S + + DYE R+ ++ + SP L + Sbjct: 3261 GKVVYSISNNTVEFSSVSYISINPVTGVIYALQSFDYEQDREFLIQIMAKDSGSPSLNSS 3320 Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPAYDAD--VTDKLQYRI--L 832 V I VTD NDN PV ++ N + P+ V A D D + ++ Y Sbjct: 3321 AIVNITVTDFNDNFPVFTQ-EVYKVNIHENIPINSTVLHVNASDKDEGINAQITYSFSTT 3379 Query: 833 SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 S N + +N G + + L+ + + TD Sbjct: 3380 SANVLRMFYINPQNGEIKIKGTLDRERSSHYNITIQATD 3418 Score = 355 bits (872), Expect = 1e-95 Identities = 250/828 (30%), Positives = 408/828 (49%), Gaps = 69/828 (8%) Query: 99 LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158 ++T ++LDREK + Y + + ATD+ SP LSS I ++I+D NDN P F + Y V Sbjct: 1337 IITSSALDREKASWYNITILATDRGSP---ELSSRKFIRLDILDVNDNPPIFIKSVYNVY 1393 Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQ-----MQFSIDSLSGDVSLVK 213 + E+ I +I A D D+G N+ + Y+I NT+ FSI+ +G + + Sbjct: 1394 LPENN--LPGASIYRIHALDLDMGDNAKVIYSISNTNTEDFPVSSYFSINIETGVLYAQR 1451 Query: 214 TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIG 273 + D+EQ + + + I A DGG+P R+ T + + + D NDN P F +++ S+SEN PI Sbjct: 1452 SFDHEQDKEFHMHIAASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISENTPIN 1511 Query: 274 YSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQ 333 +++RV A D DEG NA++TY+ + +I+P SG + T LDRE Q ++ Sbjct: 1512 STVLRVNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEITTKKPLDREAQTSHE 1571 Query: 334 LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393 L++TA+DGG+P R+ TA F Y V ++E+ G+ V+ +A Sbjct: 1572 LILTASDGGNPVRTGTALIQIIVTDANDNLPVFTEVLYTVSISENTAVGSVVL---CVNA 1628 Query: 394 DEDNRLHYEITGGNTRG-RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT 452 + ++ Y I+ NT FSI + G++ Q D++Q +++ + + A D+G S T Sbjct: 1629 SSNAKITYSISETNTMSPYFSINIET--GVLYAQQSFDYEQHKQFEMEIMAKDNGFPSMT 1686 Query: 453 A--------MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS-------- 496 + + ++ +TDAN+ APVF YT S+ E+AP+ VL V+ATD Sbjct: 1687 SNTTLLIHIIDRVVVTDANDNAPVFTEEVYTVSISENAPVNAIVLCVNATDKDEVLHVNA 1746 Query: 497 ---DVGINAQITYS-LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552 D G NAQITYS + + +S+ F IN +TG + + D E + + + Sbjct: 1747 TDRDEGTNAQITYSFIKTSVSS--------YFSINIETGVLYAQRSFDYEQDKEFHMHIA 1798 Query: 553 ARDGGVPSLSDTTD------VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 A+D G PSLS T +++ + DVNDN PVF++ LYT + E+ L G S+ V AT Sbjct: 1799 AKDNGSPSLSSNTTLSSRKFIKLDISDVNDNPPVFRKSLYTTYLPENNLPGASIYTVHAT 1858 Query: 607 DADVGLNGRIHYELDPKDREE----GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 D D G N ++ Y + + E+ F I+ +GV+ ++ D E ++ Sbjct: 1859 DVDSGDNAKLIYSISNANTEDFPVSSYFSINIETGVLYAQRSFDYEQQKEFQMQITQGRS 1918 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 G + + I D ND+ PVF D ++EN P+ +T+ + A D DEG NA + Sbjct: 1919 G-----HLMSFRVVITDANDNFPVFSKDVYKTTVNENMPVNSTVISVTASDKDEGTNAQI 1973 Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEI 782 YS +++ F++ G + + D + ES + +P ++I Sbjct: 1974 TYSFIQLSETSPFTISQHTGEIRTSQAPL-DRETESIHELVLTAFDGGNPVQTGTAIIKI 2032 Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPAYDADVTDKLQ---YRILSGNNA- 837 +V+D NDNAP+ ++ + + PV RV A D D Q Y S A Sbjct: 2033 IVSDFNDNAPIFTQ-EVYTVSLNENIPVNSTILRVSANDKDEGSNSQITYYFAASSKQAM 2091 Query: 838 NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG---VNEIKAMMQL 882 N +++ +G + L+ K + V DG V+ K ++Q+ Sbjct: 2092 NTFIIDSISGEVKTKENLDFEKIKHYEISVQAKDGGGLVSHAKILIQI 2139 Score = 348 bits (856), Expect = 1e-93 Identities = 261/916 (28%), Positives = 442/916 (48%), Gaps = 88/916 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++++LD ND+ P+F Y + E G ++ + A D D+G NA+V Y+I Sbjct: 1372 RLDILDVNDNPPIFIKSVYNVYLPENNLPGASIYRIHALDLDMGDNAKVIYSI-----SN 1426 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N ED V F I+ +G L + S D E+ + + + A+D +PV Sbjct: 1427 TNTED---------FPVSSYFSINIETGVLYAQRSFDHEQDKEFHMHIAASDGGTPVR-- 1475 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + TA I V + D NDN P F+++ Y VS+ E+ + N + ++ A+D D G N+ I Y Sbjct: 1476 -TGTALIRVIVTDANDNTPVFTQEVYKVSISENTPI--NSTVLRVNASDMDEGTNAQITY 1532 Query: 190 AI----IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 + + FSI+ SG+++ K LD E S+ L++ A DGG+P R+ T + I Sbjct: 1533 SFSRTSVNSLHASMFSINPTSGEITTKKPLDREAQTSHELILTASDGGNPVRTGTALIQI 1592 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 + D NDN P F L+ S+SEN +G ++ V A NA++TY++++ T + Sbjct: 1593 IVTDANDNLPVFTEVLYTVSISENTAVGSVVLCVNA-----SSNAKITYSISE---TNTM 1644 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT------XXXXXXXX 359 +I+ +G +Y D E ++++ + A D G P ++ T Sbjct: 1645 SPYFSINIETGVLYAQQSFDYEQHKQFEMEIMAKDNGFPSMTSNTTLLIHIIDRVVVTDA 1704 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT----GGNTRGRFSI- 414 F Y V ++E+ P V+ + ATD DE LH T G N + +S Sbjct: 1705 NDNAPVFTEEVYTVSISENAPVNAIVLCVNATDKDE--VLHVNATDRDEGTNAQITYSFI 1762 Query: 415 -TSQNG-------RGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAM-----VQIN 458 TS + G++ + D++Q++ + + ++A D+G S+T + ++++ Sbjct: 1763 KTSVSSYFSINIETGVLYAQRSFDYEQDKEFHMHIAAKDNGSPSLSSNTTLSSRKFIKLD 1822 Query: 459 ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518 I+D N+ PVF + YT + E+ G ++ V ATD D G NA++ YS+S+ +N Sbjct: 1823 ISDVNDNPPVFRKSLYTTYLPENNLPGASIYTVHATDVDSGDNAKLIYSISN--ANTEDF 1880 Query: 519 HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT-ARDGGVPSLSDTTDVEISVVDVNDN 577 F IN +TG + + D E + + +T R G + S + + D NDN Sbjct: 1881 PVSSYFSINIETGVLYAQRSFDYEQQKEFQMQITQGRSGHLMSF------RVVITDANDN 1934 Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637 PVF + +Y + E+ V ++V V A+D D G N +I Y E F I +G Sbjct: 1935 FPVFSKDVYKTTVNENMPVNSTVISVTASDKDEGTNAQITYSFIQLS-ETSPFTISQHTG 1993 Query: 638 VIRTNKA-LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696 IRT++A LDRE+ + H+L A DGG P Q+ T I+ I + D ND+ P+F + T + Sbjct: 1994 EIRTSQAPLDRETESIHELVLTAFDGGNPVQTGTAIIKIIVSDFNDNAPIFTQEVYTVSL 2053 Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS--NSFSLETRQGSDKAELVTMVDL 754 +EN P+ +TI + A+D DEG N+ + Y N+F +++ G E+ T +L Sbjct: 2054 NENIPVNSTILRVSANDKDEGSNSQITYYFAASSKQAMNTFIIDSISG----EVKTKENL 2109 Query: 755 DYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GP 812 D+E K YE+ ++A L + ++ I + D NDN PV ++ + + P+ Sbjct: 2110 DFEK-IKHYEISVQAKDGGGLVSHAKILIQIIDFNDNLPVFSQ-EVYKVSINENIPINST 2167 Query: 813 FGRVPAYDAD--VTDKLQYRILSGNN--ANLILLNETTGSMTLSPQLNTNVPKLATMEVS 868 V A D D + +++Y + + N ++N +G++ L+ KL + V Sbjct: 2168 ILYVSANDKDEGINSQIRYYFSTSSKQILNTFIINSISGAIMTKENLDFEKTKLYEISVQ 2227 Query: 869 VTDG---VNEIKAMMQ 881 DG V+ K ++Q Sbjct: 2228 AKDGGGLVSHAKVLIQ 2243 Score = 347 bits (854), Expect = 2e-93 Identities = 272/933 (29%), Positives = 442/933 (47%), Gaps = 64/933 (6%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 I ++ V D ND++PVF + Y S+ E A VL + ATD+D EV + + Sbjct: 1695 IIDRVVVTDANDNAPVFTEEVYTVSISENAPVNAIVLCVNATDKD-----EV---LHVNA 1746 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 D +A V F I+ +G L + S D E+ + + + A D SP Sbjct: 1747 TDRDEGTNAQITYSFIKTSVSSYFSINIETGVLYAQRSFDYEQDKEFHMHIAAKDNGSPS 1806 Query: 127 ---SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183 + LSS I ++I D NDN P F + YT + E+ I + ATD D G Sbjct: 1807 LSSNTTLSSRKFIKLDISDVNDNPPVFRKSLYTTYLPENN--LPGASIYTVHATDVDSGD 1864 Query: 184 NSAIRYAIIGGNTQ-----MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238 N+ + Y+I NT+ FSI+ +G + ++ DYEQ + +++ I G Sbjct: 1865 NAKLIYSISNANTEDFPVSSYFSINIETGVLYAQRSFDYEQQKEFQMQITQGRSG----- 1919 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 + + I D NDN P F +++ +V+EN+P+ +++ V A D DEG NA++TY+ Sbjct: 1920 HLMSFRVVITDANDNFPVFSKDVYKTTVNENMPVNSTVISVTASDKDEGTNAQITYSFIQ 1979 Query: 299 KDYTGNVDLPITIDPRSGWVYTS-GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357 T P TI +G + TS LDRET++ ++L++TA DGG+P ++ TA Sbjct: 1980 LSETS----PFTISQHTGEIRTSQAPLDRETESIHELVLTAFDGGNPVQTGTAIIKIIVS 2035 Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSIT 415 F Y V L E+ P + ++ ++A D DE ++++ Y + + + Sbjct: 2036 DFNDNAPIFTQEVYTVSLNENIPVNSTILRVSANDKDEGSNSQITYYFAASSKQAMNTFI 2095 Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYT 475 + G + + LDF++ + Y ++V A D GG A + I I D N+ PVF Y Sbjct: 2096 IDSISGEVKTKENLDFEKIKHYEISVQAKDGGGLVSHAKILIQIIDFNDNLPVFSQEVYK 2155 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 S+ E+ PI +T+L VSA D D GIN+QI Y S+ S++ + + F+IN +GAI T Sbjct: 2156 VSINENIPINSTILYVSANDKDEGINSQIRYYFST--SSKQILN---TFIINSISGAIMT 2210 Query: 536 NKLLDRETMSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 + LD E Y ++V A+D GG+ S + + V D+NDN PVFK Y A I E+ Sbjct: 2211 KENLDFEKTKLYEISVQAKDGGGLVSHAKVLIQTLDVSDINDNPPVFKYPNYLAYIPENN 2270 Query: 595 LVGTSVSQVGATDADVGLNGRIHY---ELDPKDREEGSFV-IDPASGVIRTNKALDRESV 650 G S+ + A D D N ++ Y ++ + S++ I+P +GVI ++ D E Sbjct: 2271 QPGASIYSIQAIDNDSEENAKLIYSIINMNTGEPSPSSYISINPVTGVIYAQRSFDYEQD 2330 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF-----ESDCLTFY--ISENSPIG 703 ++ +A D G+PP +S+VIV I + D ND+ P+ ++ Y + +S G Sbjct: 2331 REFQIQIMAKDNGSPPLNSSVIVTICVTDQNDNSPLVLYPSADAGGSAAYEMVPFSSEQG 2390 Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY 763 T + ++ A D D G NA + Y +++ F ++ ELV LD E+ Y Sbjct: 2391 TLVTKVVAVDADSGHNAWLSYHFLQDSETSYFVID-----QYTELVLKTSLDREN-ENFY 2444 Query: 764 ELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPA 818 E+V+ A +P + I VTD NDN P+ +++ N + Sbjct: 2445 EIVLTAFDGGNPMQTGTALIRITVTDANDNFPMFSQEIYKVSINENMPLNSTVLYVSASD 2504 Query: 819 YDADVTDKLQYRILSGNN--ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG---V 873 D + +L Y S + N +N +G + L+ K + V DG + Sbjct: 2505 KDEGINSQLTYSFSSASKQATNAFAINPQSGEVITKDILDFEKMKNYEIAVQAKDGGGLI 2564 Query: 874 NEIKAMMQ-LSVRLITEEMLLNSITVRLNDMTA 905 + K ++Q L E+ L SIT +++ +A Sbjct: 2565 SHAKVLIQILDENDNPPEVSLTSITNPVSEESA 2597 Score = 332 bits (817), Expect = 6e-89 Identities = 255/806 (31%), Positives = 397/806 (49%), Gaps = 65/806 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I ++D ND+ PVF + Y+ S+ E +T+L + A D+D G N+++ Y + L Sbjct: 2137 IQIIDFNDNLPVFSQEVYKVSINENIPINSTILYVSANDKDEGINSQIRYYFSTSSKQIL 2196 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N F I+ SGA++T+ +LD EK Y + V+A D VS Sbjct: 2197 N-----------------TFIINSISGAIMTKENLDFEKTKLYEISVQAKDGGGLVSHAK 2239 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 T+ V+ D NDN P F Y + E+ I I+A D D N+ + Y+ Sbjct: 2240 VLIQTLDVS--DINDNPPVFKYPNYLAYIPENNQ--PGASIYSIQAIDNDSEENAKLIYS 2295 Query: 191 IIGGNT-----QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 II NT SI+ ++G + ++ DYEQ R +++ I A+D GSP +++ + I Sbjct: 2296 IINMNTGEPSPSSYISINPVTGVIYAQRSFDYEQDREFQIQIMAKDNGSPPLNSSVIVTI 2355 Query: 246 NIRDVNDNAPR-FYTSLFQ--ESVSENVPI----GYSIVRVQAYDADEGVNAELTYTMTD 298 + D NDN+P Y S + E VP G + +V A DAD G NA L+Y Sbjct: 2356 CVTDQNDNSPLVLYPSADAGGSAAYEMVPFSSEQGTLVTKVVAVDADSGHNAWLSYHFLQ 2415 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358 T ID + V + LDRE + Y++++TA DGG+P ++ TA Sbjct: 2416 DSETSY----FVIDQYTELVLKTS-LDRENENFYEIVLTAFDGGNPMQTGTALIRITVTD 2470 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGR--FSI 414 F Y+V + E+ P + V+ ++A+D DE +++L Y + + + F+I Sbjct: 2471 ANDNFPMFSQEIYKVSINENMPLNSTVLYVSASDKDEGINSQLTYSFSSASKQATNAFAI 2530 Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPY 474 Q+G + LDF++ + Y + V A D GG A V I I D N+ P Sbjct: 2531 NPQSGE--VITKDILDFEKMKNYEIAVQAKDGGGLISHAKVLIQILDENDNPPEVSLTSI 2588 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 T V E++ GT V ++ A D D GINAQITYS S+ S +A + F IN +G I Sbjct: 2589 TNPVSEESAPGTVVALI-ANDKDEGINAQITYSFSA-TSKQA----SRSFAINAISGEIK 2642 Query: 535 TNKLLDRETMSGYLLTVTAR---DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 T + +D E Y ++V AR DGG P + T + I+V D+NDN P+F Q++YT +I Sbjct: 2643 TKENIDFEKTKYYEISVQARISFDGGSPMQTGTALIRITVTDMNDNFPIFGQEVYTVSIN 2702 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG-SFVIDPASGVIRTNKALDRESV 650 E+ + ++V V A D D G+N +I Y ++ SF I+ +G I+T + LD E Sbjct: 2703 ENIPLNSTVLCVSANDKDQGINSQITYSFSATSKQASRSFSINSETGEIKTKENLDFEKT 2762 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710 +++ +V S + + I + D ND+ PVF + I EN PI +T+ ++ Sbjct: 2763 KNYEI-SVQAKIQKHHILSLINIQITVTDFNDNFPVFTQEVYKVNIHENIPIHSTVLQVN 2821 Query: 711 AHDPDEGPNAVVHYSIKGGDDSN---SFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 A D DEG NA + YS G +N F++ + G E+ T ++D+E K Y++ + Sbjct: 2822 ASDKDEGINAQITYSF-GTTATNVLRIFAINPKSG----EITTKGNVDFEE-TKYYDISV 2875 Query: 768 RAA-SPPLWNDVRVEILVTDVNDNAP 792 +A L + +V I + D NDNAP Sbjct: 2876 QAQDGGSLASHAKVLIQILDENDNAP 2901 Score = 321 bits (788), Expect = 2e-85 Identities = 254/831 (30%), Positives = 385/831 (46%), Gaps = 64/831 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++++ D ND++PVF Y + V + G + + A D D G NA + Y + + + Sbjct: 464 KLDISDVNDNAPVFTKSSYVSMVPVASEQGALITKVVAVDADSGHNAWLSYHVVQGSEPS 523 Query: 70 LNPEDAXXXXXXXXXXVQDVFR------------IDG----RSGALLTRASL----DREK 109 L QD R DG RSG L R ++ D Sbjct: 524 LFSISQNTGEIRTSRVFQDKDRETQTIHELILTASDGGNPVRSGTALIRIAVTDANDNLP 583 Query: 110 VAR---YTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVT 166 V Y V + V D+ S I ++I D NDN P F++ +Y + E+ Sbjct: 584 VFTQEVYKVSISTLIALIEVHDQDSDIKLIKLDISDVNDNAPVFTKSSYVAYIAENNLAG 643 Query: 167 DNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ-----FSIDSLSGDVSLVKTLDYEQVR 221 + I +I+A+D D G N+ I Y+I +T+ FSI+ +G + K LD E Sbjct: 644 AS--IYRIQASDIDAGDNAKIIYSIYNTDTEDYSMSSFFSINIETGVLYAQKPLDRETQS 701 Query: 222 SYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA 281 + L++ A DGG+P R+ T + I + D NDN P F +++ S+SEN PI S++ + A Sbjct: 702 IHELILTASDGGNPLRTGTALIRIIVTDSNDNLPVFTQEVYKVSISENAPINSSVIILTA 761 Query: 282 YDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATD 340 D DEG NA++TY+++ I+P G + + LDRETQ ++L++TA+D Sbjct: 762 TDKDEGTNAQITYSISKTSENNFYTSVFNINPVMGEITIKEKPLDRETQKDHELILTASD 821 Query: 341 GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNR 398 GGDP ++ TA F Y+V ++E+ P + V+ + ATD DE + + Sbjct: 822 GGDPVKTGTAIIRIIVTDANDNLPVFTKAVYKVSISENIPINSSVLHVNATDRDEGTNAQ 881 Query: 399 LHYEI--TGGNT--RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM 454 + Y T N FSI NG I Q LDF+ R Y ++V ATD GG + Sbjct: 882 ITYSFIKTSENDIHSPMFSINQINGE--IKTLQKLDFELTRNYEMSVQATDGGGFVAHSK 939 Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 V + I + N+ AP + + ED+ GT + ++ D D G N + L Sbjct: 940 VLLEIINENDNAPEITMTSVSTPIPEDSEPGTVIALIKVHDHDSGENGEAECHLLGSPPF 999 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 + V+ + I T +LDRE + Y +T+ A D G P LS + + + DV Sbjct: 1000 QLVSTSSSYY-------RIITTSVLDREKVQLYNITILANDKGSPQLSSRKSILLDISDV 1052 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE----EGSF 630 NDN PVF + Y A + E+ L G S+ +V A+D D G N ++ Y + + E F Sbjct: 1053 NDNPPVFLKSRYIAYLPENNLPGASIYKVQASDLDTGENSKVIYSVFNTNTEAFPVSSYF 1112 Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND-SPPVFES 689 I+ +GV+ ++ D E + A D G P SS + I+I D ND +P +F Sbjct: 1113 SINIETGVLYAQRSFDYEQHKEFAMHVQAKDNGYPSLSSNATLIIRIIDQNDNAPKMFIK 1172 Query: 690 DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD-----SNSFSLETRQGSD 744 T Y+ EN+ G TI I A D D G NA V YSI + S+ FS+ G Sbjct: 1173 SAYTIYLPENNLPGATIYRIHALDLDMGDNAKVIYSISNTNTEDFPVSSYFSINIETG-- 1230 Query: 745 KAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792 L DYE K++ + I A SP L ++ + I + D NDNAP Sbjct: 1231 --VLYAQRSFDYEQD-KEFHMHIAAKDNGSPSLSSNTTLIIRIMDQNDNAP 1278 Score = 313 bits (768), Expect = 5e-83 Identities = 234/820 (28%), Positives = 383/820 (46%), Gaps = 68/820 (8%) Query: 5 FCIHQQI--NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 F H ++ +++ ND++P M + E + GT + +K D D G+N E E Sbjct: 934 FVAHSKVLLEIINENDNAPEITMTSVSTPIPEDSEPGTVIALIKVHDHDSGENGEAE--C 991 Query: 63 ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122 L+ + +RI +T + LDREKV Y + + A D+ Sbjct: 992 HLLGSPPFQ----------LVSTSSSYYRI-------ITTSVLDREKVQLYNITILANDK 1034 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 SP +LSS +I ++I D NDN P F + Y + E + I K++A+D D G Sbjct: 1035 GSP---QLSSRKSILLDISDVNDNPPVFLKSRYIAYLPE--NNLPGASIYKVQASDLDTG 1089 Query: 183 ANSAIRYAIIGGNTQ-----MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237 NS + Y++ NT+ FSI+ +G + ++ DYEQ + + + ++A+D G PS Sbjct: 1090 ENSKVIYSVFNTNTEAFPVSSYFSINIETGVLYAQRSFDYEQHKEFAMHVQAKDNGYPSL 1149 Query: 238 SNTTQLLINIRDVNDNAPR-FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 S+ L+I I D NDNAP+ F S + + EN G +I R+ A D D G NA++ Y++ Sbjct: 1150 SSNATLIIRIIDQNDNAPKMFIKSAYTIYLPENNLPGATIYRIHALDLDMGDNAKVIYSI 1209 Query: 297 TDKDYTGNVDLPI----TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352 ++ T D P+ +I+ +G +Y D E ++ + + A D G P S+ T Sbjct: 1210 SN---TNTEDFPVSSYFSINIETGVLYAQRSFDYEQDKEFHMHIAAKDNGSPSLSSNTTL 1266 Query: 353 XXXXXXXXXXXXXFMPGQYEV--ELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG 410 + E L + P + L + + +++ + GN Sbjct: 1267 IIRIMDQNDNAPKILYPSTESGDSLLFEMVPFASIEALISIQEKSGHPVYFSLRWGNPTE 1326 Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPV 468 R I + LD ++ Y +T+ ATD G S ++++I D N+ P+ Sbjct: 1327 HLKTAFIFYR--IITSSALDREKASWYNITILATDRGSPELSSRKFIRLDILDVNDNPPI 1384 Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528 F + Y + E+ G ++ + A D D+G NA++ YS+S+ +N F IN Sbjct: 1385 FIKSVYNVYLPENNLPGASIYRIHALDLDMGDNAKVIYSISN--TNTEDFPVSSYFSINI 1442 Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588 +TG + + D E + + + A DGG P + T + + V D NDN PVF Q++Y Sbjct: 1443 ETGVLYAQRSFDHEQDKEFHMHIAASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKV 1502 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYEL---DPKDREEGSFVIDPASGVIRTNKAL 645 +I E+ + ++V +V A+D D G N +I Y F I+P SG I T K L Sbjct: 1503 SISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEITTKKPL 1562 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 DRE+ +H+L A DGG P ++ T ++ I + D ND+ PVF T ISEN+ +G+ Sbjct: 1563 DREAQTSHELILTASDGGNPVRTGTALIQIIVTDANDNLPVFTEVLYTVSISENTAVGSV 1622 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765 + + A NA + YSI ++N+ S + L DYE K++E+ Sbjct: 1623 VLCVNA-----SSNAKITYSI---SETNTMSPYFSINIETGVLYAQQSFDYEQ-HKQFEM 1673 Query: 766 VIRAAS---PPLWNDVRV------EILVTDVNDNAPVMKD 796 I A P + ++ + ++VTD NDNAPV + Sbjct: 1674 EIMAKDNGFPSMTSNTTLLIHIIDRVVVTDANDNAPVFTE 1713 Score = 311 bits (763), Expect = 2e-82 Identities = 257/913 (28%), Positives = 412/913 (45%), Gaps = 91/913 (9%) Query: 11 INVLDCNDHSP-VFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 I ++D ND++P +F Y + E G T+ + A D D+G NA+V Y+I Sbjct: 1157 IRIIDQNDNAPKMFIKSAYTIYLPENNLPGATIYRIHALDLDMGDNAKVIYSI-----SN 1211 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N ED V F I+ +G L + S D E+ + + + A D SP Sbjct: 1212 TNTED---------FPVSSYFSINIETGVLYAQRSFDYEQDKEFHMHIAAKDNGSP---S 1259 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKA-TDADVGANSAIR 188 LSS T+ + I+D NDN P+ Y + D + + A I+A + + Sbjct: 1260 LSSNTTLIIRIMDQNDNAPKI---LYPSTESGDSLLFEMVPFASIEALISIQEKSGHPVY 1316 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 +++ GN + + LD E+ Y + I A D GSP S+ + ++I Sbjct: 1317 FSLRWGNPTEHLKTAFIFYRIITSSALDREKASWYNITILATDRGSPELSSRKFIRLDIL 1376 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 DVNDN P F S++ + EN G SI R+ A D D G NA++ Y++++ T D P Sbjct: 1377 DVNDNPPIFIKSVYNVYLPENNLPGASIYRIHALDLDMGDNAKVIYSISN---TNTEDFP 1433 Query: 309 I----TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 + +I+ +G +Y D E ++ + + A+DGG P R+ TA Sbjct: 1434 VSSYFSINIETGVLYAQRSFDHEQDKEFHMHIAASDGGTPVRTGTALIRVIVTDANDNTP 1493 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT------RGRFSITSQN 418 F Y+V ++E+ P + V+ + A+D DE + T FSI + Sbjct: 1494 VFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTS 1553 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTA 476 G IT +PLD + + + L ++A+D G R+ TA++QI +TDAN+ PVF YT Sbjct: 1554 GE--ITTKKPLDREAQTSHELILTASDGGNPVRTGTALIQIIVTDANDNLPVFTEVLYTV 1611 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 S+ E+ +G+ VL V+A+ NA+ITYS+S +N + F IN +TG + Sbjct: 1612 SISENTAVGSVVLCVNASS-----NAKITYSISE--TNTMSPY----FSINIETGVLYAQ 1660 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV------DVNDNEPVFKQQLYTANI 590 + D E + + + A+D G PS++ T + I ++ D NDN PVF +++YT +I Sbjct: 1661 QSFDYEQHKQFEMEIMAKDNGFPSMTSNTTLLIHIIDRVVVTDANDNAPVFTEEVYTVSI 1720 Query: 591 MEDALVGT-----------SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639 E+A V V V ATD D G N +I Y K F I+ +GV+ Sbjct: 1721 SENAPVNAIVLCVNATDKDEVLHVNATDRDEGTNAQITYSF-IKTSVSSYFSINIETGVL 1779 Query: 640 RTNKALDRESVATHDLKAVAIDGGTPPQSSTV------IVHIKIEDINDSPPVFESDCLT 693 ++ D E + A D G+P SS + + I D+ND+PPVF T Sbjct: 1780 YAQRSFDYEQDKEFHMHIAAKDNGSPSLSSNTTLSSRKFIKLDISDVNDNPPVFRKSLYT 1839 Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD-----SNSFSLETRQGSDKAEL 748 Y+ EN+ G +I + A D D G NA + YSI + S+ FS+ G L Sbjct: 1840 TYLPENNLPGASIYTVHATDVDSGDNAKLIYSISNANTEDFPVSSYFSINIETG----VL 1895 Query: 749 VTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCF 808 DYE ++ + + S L + +++TD NDN PV + + Sbjct: 1896 YAQRSFDYEQQKEFQMQITQGRSGHL---MSFRVVITDANDNFPVFSK-DVYKTTVNENM 1951 Query: 809 PV-GPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSM-TLSPQLNTNVPKLAT 864 PV V A D D ++ Y + + + +++ TG + T L+ + Sbjct: 1952 PVNSTVISVTASDKDEGTNAQITYSFIQLSETSPFTISQHTGEIRTSQAPLDRETESIHE 2011 Query: 865 MEVSVTDGVNEIK 877 + ++ DG N ++ Sbjct: 2012 LVLTAFDGGNPVQ 2024 Score = 308 bits (757), Expect = 1e-81 Identities = 248/917 (27%), Positives = 430/917 (46%), Gaps = 81/917 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I V D ND+ PVF + Y+ S+ E A ++V+ L ATD+D G NA++ Y+I + + Sbjct: 724 RIIVTDSNDNLPVFTQEVYKVSISENAPINSSVIILTATDKDEGTNAQITYSISKTSENN 783 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS-LDREKVARYTVLVKATDQASPVSD 128 VF I+ G + + LDRE + +++ A+D PV Sbjct: 784 F---------------YTSVFNINPVMGEITIKEKPLDRETQKDHELILTASDGGDPVK- 827 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 + TA I + + D NDN P F++ Y VS+ E+I + N + + ATD D G N+ I Sbjct: 828 --TGTAIIRIIVTDANDNLPVFTKAVYKVSISENIPI--NSSVLHVNATDRDEGTNAQIT 883 Query: 189 YAIIGGNTQ----MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 Y+ I + FSI+ ++G++ ++ LD+E R+Y + ++A DGG + ++L Sbjct: 884 YSFIKTSENDIHSPMFSINQINGEIKTLQKLDFELTRNYEMSVQATDGGGFVAHS--KVL 941 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + I + NDNAP + + E+ G I ++ +D D G N E + G+ Sbjct: 942 LEIINENDNAPEITMTSVSTPIPEDSEPGTVIALIKVHDHDSGENGE-----AECHLLGS 996 Query: 305 VDLPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 + S + + T+ LDRE Y + + A D G P S+ + Sbjct: 997 PPFQLVSTSSSYYRIITTSVLDREKVQLYNITILANDKGSPQLSSRKSILLDISDVNDNP 1056 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG-- 419 F+ +Y L E+ PG + + A+D D E++++ Y + NT F ++S Sbjct: 1057 PVFLKSRYIAYLPENNLPGASIYKVQASDLDTGENSKVIYSVFNTNTEA-FPVSSYFSIN 1115 Query: 420 --RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAP-VFENAPY 474 G++ + D++Q + + + V A D+G S A + I I D N+ AP +F + Y Sbjct: 1116 IETGVLYAQRSFDYEQHKEFAMHVQAKDNGYPSLSSNATLIIRIIDQNDNAPKMFIKSAY 1175 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 T + E+ G T+ + A D D+G NA++ YS+S+ + + F IN +TG + Sbjct: 1176 TIYLPENNLPGATIYRIHALDLDMGDNAKVIYSISNTNTEDFPV--SSYFSINIETGVLY 1233 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 + D E + + + A+D G PSLS T + I ++D NDN P LY + D+ Sbjct: 1234 AQRSFDYEQDKEFHMHIAAKDNGSPSLSSNTTLIIRIMDQNDNAPKI---LYPSTESGDS 1290 Query: 595 LVGTSVSQVGATDADVGLNGR----IHYEL---DPKDREEGSFVIDPASGVIRTNKALDR 647 L+ V + +A + + + +++ L +P + + +F+ I T+ ALDR Sbjct: 1291 LLFEMVP-FASIEALISIQEKSGHPVYFSLRWGNPTEHLKTAFIFYR----IITSSALDR 1345 Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 E + +++ +A D G+P SS + + I D+ND+PP+F Y+ EN+ G +I Sbjct: 1346 EKASWYNITILATDRGSPELSSRKFIRLDILDVNDNPPIFIKSVYNVYLPENNLPGASIY 1405 Query: 708 EIRAHDPDEGPNAVVHYSIKGGDD-----SNSFSLETRQGSDKAELVTMVDLDYESPRKK 762 I A D D G NA V YSI + S+ FS+ G L D+E K+ Sbjct: 1406 RIHALDLDMGDNAKVIYSISNTNTEDFPVSSYFSINIETGV----LYAQRSFDHEQD-KE 1460 Query: 763 YELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPA 818 + + I A+ +P + ++VTD NDN PV ++ + + P+ RV A Sbjct: 1461 FHMHIAASDGGTPVRTGTALIRVIVTDANDNTPVFTQ-EVYKVSISENTPINSTVLRVNA 1519 Query: 819 YDAD------VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 D D +T ++ +A++ +N T+G +T L+ + ++ +DG Sbjct: 1520 SDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEITTKKPLDREAQTSHELILTASDG 1579 Query: 873 VNEIKAMMQLSVRLITE 889 N ++ L ++T+ Sbjct: 1580 GNPVRTGTALIQIIVTD 1596 Score = 277 bits (680), Expect = 2e-72 Identities = 189/627 (30%), Positives = 306/627 (48%), Gaps = 36/627 (5%) Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS 164 LDRE + + +++ ATD +P + + TA + + + D NDN P F+++ Y +S+ E Sbjct: 1 LDRETLNFHELILTATDGGNP---KRTGTALLRIIVTDYNDNVPVFTQQVYKISISESAP 57 Query: 165 VTDNPVIAKIKATDADVGANSAIRYAII-----GGNTQMQFSIDSLSGDVSLVKTLDYEQ 219 + N + + ATD D G N I Y+ +TQM F+I+ +G++ L++E Sbjct: 58 I--NSTVTVVTATDKDDGTNGHITYSFSRTAENAFHTQM-FNINPANGEIKTKGHLNFEV 114 Query: 220 VRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRV 279 + Y + ++A+DGG + ++LI I D NDNAP + + E+ G I + Sbjct: 115 TKHYEMSVQAKDGGGLLAQS--KVLIEIIDENDNAPEISIASLSTPIPEDSAPGTLIALI 172 Query: 280 QAYDADEGVNAELT-YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA 338 + +D D G N E + + + R + +G LDRE Y + + A Sbjct: 173 EVHDQDSGENGEAECHILGSSPFHKFRKWKPLSSSRYYKIVNTGSLDRELVPWYNITILA 232 Query: 339 TDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR 398 TD G P S F+ Y+ ++E+ P T V+ + ATD + + Sbjct: 233 TDRGSPQLSTMKFIKLDISDVNDNPPMFVKSVYKASISENSPVNTTVLYVNATDKVKHQK 292 Query: 399 LHYEITGGN--TRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAM 454 + + + + FSI + G ++ + D++Q + + + ++A+D G RS TA+ Sbjct: 293 IAFIMDNEDFPISSYFSINIETG--VLYAQRSFDYEQVKEFQIQITASDGGNPVRSGTAL 350 Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 ++I +TD+N+ PVF Y S+ E+ PI +TVL V+ATD D G NAQI YS S N Sbjct: 351 IRIAVTDSNDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQIMYSFSKTSGN 410 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG---VPSLSDTTDVEISV 571 H F IN +G I T + + E Y ++V A+DGG S +++ + Sbjct: 411 NL---HTSMFSINYTSGEIKTKQNFNFEAKKFYEISVQAKDGGGFVAHSKILIKLIKLDI 467 Query: 572 VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631 DVNDN PVF + Y + + + G +++V A DAD G N + Y + + E F Sbjct: 468 SDVNDNAPVFTKSSYVSMVPVASEQGALITKVVAVDADSGHNAWLSYHV-VQGSEPSLFS 526 Query: 632 IDPASGVIRTNKAL---DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688 I +G IRT++ DRE+ H+L A DGG P +S T ++ I + D ND+ PVF Sbjct: 527 ISQNTGEIRTSRVFQDKDRETQTIHELILTASDGGNPVRSGTALIRIAVTDANDNLPVFT 586 Query: 689 SDCLTFYISENSPIGTTIGEIRAHDPD 715 + + +S I T I I HD D Sbjct: 587 QE--VYKVS----ISTLIALIEVHDQD 607 Score = 250 bits (613), Expect = 3e-64 Identities = 175/596 (29%), Positives = 285/596 (47%), Gaps = 29/596 (4%) Query: 215 LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY 274 LD E + + L++ A DGG+P R+ T L I + D NDN P F +++ S+SE+ PI Sbjct: 1 LDRETLNFHELILTATDGGNPKRTGTALLRIIVTDYNDNVPVFTQQVYKISISESAPINS 60 Query: 275 SIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQL 334 ++ V A D D+G N +TY+ + I+P +G + T G L+ E Y++ Sbjct: 61 TVTVVTATDKDDGTNGHITYSFSRTAENAFHTQMFNINPANGEIKTKGHLNFEVTKHYEM 120 Query: 335 LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394 V A DGG A + + ED PGT + + D D Sbjct: 121 SVQAKDGGG--LLAQSKVLIEIIDENDNAPEISIASLSTPIPEDSAPGTLIALIEVHDQD 178 Query: 395 --EDNRLHYEITGGNTRGRF----SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG 448 E+ I G + +F ++S ++ LD + Y +T+ ATD G Sbjct: 179 SGENGEAECHILGSSPFHKFRKWKPLSSSRYYKIVNTGS-LDRELVPWYNITILATDRGS 237 Query: 449 RSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506 + M ++++I+D N+ P+F + Y AS+ E++P+ TTVL V+ATD + +I + Sbjct: 238 PQLSTMKFIKLDISDVNDNPPMFVKSVYKASISENSPVNTTVLYVNATDKVK--HQKIAF 295 Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566 + +E + ++ + F IN +TG + + D E + + + +TA DGG P S T Sbjct: 296 IMDNE--DFPISSY---FSINIETGVLYAQRSFDYEQVKEFQIQITASDGGNPVRSGTAL 350 Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP---K 623 + I+V D NDN PVF Q++Y +I E+ + ++V V ATD D G N +I Y Sbjct: 351 IRIAVTDSNDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQIMYSFSKTSGN 410 Query: 624 DREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV---IVHIKIEDI 680 + F I+ SG I+T + + E+ +++ A DGG S + ++ + I D+ Sbjct: 411 NLHTSMFSINYTSGEIKTKQNFNFEAKKFYEISVQAKDGGGFVAHSKILIKLIKLDISDV 470 Query: 681 NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR 740 ND+ PVF + S G I ++ A D D G NA + Y + G + + FS+ Sbjct: 471 NDNAPVFTKSSYVSMVPVASEQGALITKVVAVDADSGHNAWLSYHVVQGSEPSLFSISQN 530 Query: 741 QGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPV 793 G + V D D E+ + +EL++ A+ +P + I VTD NDN PV Sbjct: 531 TGEIRTSRV-FQDKDRET-QTIHELILTASDGGNPVRSGTALIRIAVTDANDNLPV 584 Score = 246 bits (601), Expect = 9e-63 Identities = 182/600 (30%), Positives = 291/600 (48%), Gaps = 54/600 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I V D ND+ PVF Q Y+ S+ E A +TV + ATD+D G N + Y+ + Sbjct: 30 RIIVTDYNDNVPVFTQQVYKISISESAPINSTVTVVTATDKDDGTNGHITYSFSRTAENA 89 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + + +F I+ +G + T+ L+ E Y + V+A D Sbjct: 90 FHTQ---------------MFNINPANGEIKTKGHLNFEVTKHYEMSVQAKDGGG----- 129 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L + + + + IID+NDN P+ S + + + ED + +IA I+ D D G N Sbjct: 130 LLAQSKVLIEIIDENDNAPEISIASLSTPIPEDSA--PGTLIALIEVHDQDSGENGEAEC 187 Query: 190 AIIGGNTQMQF---SIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 I+G + +F S S +V T LD E V Y + I A D GSP S + Sbjct: 188 HILGSSPFHKFRKWKPLSSSRYYKIVNTGSLDRELVPWYNITILATDRGSPQLSTMKFIK 247 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 ++I DVNDN P F S+++ S+SEN P+ +++ V A D+ + ++ + M ++D+ + Sbjct: 248 LDISDVNDNPPMFVKSVYKASISENSPVNTTVLYVNA--TDKVKHQKIAFIMDNEDFPIS 305 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 I I+ +G +Y D E ++Q+ +TA+DGG+P RS TA Sbjct: 306 SYFSINIE--TGVLYAQRSFDYEQVKEFQIQITASDGGNPVRSGTALIRIAVTDSNDNLP 363 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH----YEITGGNT--RGRFSITSQN 418 F Y+V ++E+ P + V+T+ ATD DE + T GN FSI + Sbjct: 364 VFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQIMYSFSKTSGNNLHTSMFSINYTS 423 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGG-----RSDTAMVQINITDANNYAPVFENAP 473 G I Q +F+ ++ Y ++V A D GG + +++++I+D N+ APVF + Sbjct: 424 GE--IKTKQNFNFEAKKFYEISVQAKDGGGFVAHSKILIKLIKLDISDVNDNAPVFTKSS 481 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 Y + V + G + V A D+D G NA ++Y + F I+ TG I Sbjct: 482 YVSMVPVASEQGALITKVVAVDADSGHNAWLSYHVVQ-------GSEPSLFSISQNTGEI 534 Query: 534 TTNKLL---DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590 T+++ DRET + + L +TA DGG P S T + I+V D NDN PVF Q++Y +I Sbjct: 535 RTSRVFQDKDRETQTIHELILTASDGGNPVRSGTALIRIAVTDANDNLPVFTQEVYKVSI 594 Score = 225 bits (549), Expect = 2e-56 Identities = 166/580 (28%), Positives = 276/580 (47%), Gaps = 39/580 (6%) Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383 LDRET ++L++TATDGG+P R+ TA F Y++ ++E P + Sbjct: 1 LDRETLNFHELILTATDGGNPKRTGTALLRIIVTDYNDNVPVFTQQVYKISISESAPINS 60 Query: 384 PVVTLTATDADEDNRLHYEITGGNTRGR------FSITSQNGRGLITVAQPLDFKQERRY 437 V +TATD D+ H + T F+I NG I L+F+ + Y Sbjct: 61 TVTVVTATDKDDGTNGHITYSFSRTAENAFHTQMFNINPANGE--IKTKGHLNFEVTKHY 118 Query: 438 VLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497 ++V A D GG + V I I D N+ AP A + + ED+ GT + ++ D D Sbjct: 119 EMSVQAKDGGGLLAQSKVLIEIIDENDNAPEISIASLSTPIPEDSAPGTLIALIEVHDQD 178 Query: 498 VGINAQITYSLSSEISNEAVAHHDQQF--VINPQTGAITTNKLLDRETMSGYLLTVTARD 555 G N + I + H +++ + + + I LDRE + Y +T+ A D Sbjct: 179 SGENGEA----ECHILGSSPFHKFRKWKPLSSSRYYKIVNTGSLDRELVPWYNITILATD 234 Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615 G P LS +++ + DVNDN P+F + +Y A+I E++ V T+V V ATD + + Sbjct: 235 RGSPQLSTMKFIKLDISDVNDNPPMFVKSVYKASISENSPVNTTVLYVNATDKVK--HQK 292 Query: 616 IHYELDPKDREEGS-FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674 I + +D +D S F I+ +GV+ ++ D E V ++ A DGG P +S T ++ Sbjct: 293 IAFIMDNEDFPISSYFSINIETGVLYAQRSFDYEQVKEFQIQITASDGGNPVRSGTALIR 352 Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734 I + D ND+ PVF + ISEN PI +T+ + A D DEG NA + YS +N Sbjct: 353 IAVTDSNDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQIMYSFSKTSGNNL 412 Query: 735 FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP---PLWNDVRVEIL---VTDVN 788 + E+ T + ++E+ +K YE+ ++A + + ++++ ++DVN Sbjct: 413 HTSMFSINYTSGEIKTKQNFNFEA-KKFYEISVQAKDGGGFVAHSKILIKLIKLDISDVN 471 Query: 789 DNAPVMKDFQIIFNNYKDCFPVGP-----FGRVPAYDADVTDK--LQYRILSGNNANLIL 841 DNAPV ++Y PV +V A DAD L Y ++ G+ +L Sbjct: 472 DNAPVFTK-----SSYVSMVPVASEQGALITKVVAVDADSGHNAWLSYHVVQGSEPSLFS 526 Query: 842 LNETTGSMTLSPQLNTNVPKLATME---VSVTDGVNEIKA 878 +++ TG + S + T+ ++ +DG N +++ Sbjct: 527 ISQNTGEIRTSRVFQDKDRETQTIHELILTASDGGNPVRS 566 Score = 182 bits (443), Expect = 1e-43 Identities = 140/498 (28%), Positives = 220/498 (44%), Gaps = 33/498 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I ++D ND++P + + E ++ GT + ++ DQD G+N E E I L Sbjct: 138 IEIIDENDNAPEISIASLSTPIPEDSAPGTLIALIEVHDQDSGENGEAECHI-------L 190 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 ++I + SLDRE V Y + + ATD+ SP +L Sbjct: 191 GSSPFHKFRKWKPLSSSRYYKI-------VNTGSLDRELVPWYNITILATDRGSP---QL 240 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+ I ++I D NDN P F + Y S+ E+ V N + + ATD A Sbjct: 241 STMKFIKLDISDVNDNPPMFVKSVYKASISENSPV--NTTVLYVNATDKVKHQKIAFIMD 298 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 FSI+ +G + ++ DYEQV+ +++ I A DGG+P RS T + I + D Sbjct: 299 NEDFPISSYFSINIETGVLYAQRSFDYEQVKEFQIQITASDGGNPVRSGTALIRIAVTDS 358 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F +++ S+SEN+PI +++ V A D DEG NA++ Y+ + + Sbjct: 359 NDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQIMYSFSKTSGNNLHTSMFS 418 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD---PPRSATATXXXXXXXXXXXXXXFM 367 I+ SG + T + E + Y++ V A DGG + F Sbjct: 419 INYTSGEIKTKQNFNFEAKKFYEISVQAKDGGGFVAHSKILIKLIKLDISDVNDNAPVFT 478 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGR-GLIT 424 Y + G + + A DAD + L Y + G+ FSI+ G Sbjct: 479 KSSYVSMVPVASEQGALITKVVAVDADSGHNAWLSYHVVQGSEPSLFSISQNTGEIRTSR 538 Query: 425 VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 V Q D + + + L ++A+D G RS TA+++I +TDAN+ PVF Y S Sbjct: 539 VFQDKDRETQTIHELILTASDGGNPVRSGTALIRIAVTDANDNLPVFTQEVYKVS----- 593 Query: 483 PIGTTVLVVSATDSDVGI 500 I T + ++ D D I Sbjct: 594 -ISTLIALIEVHDQDSDI 610 Score = 147 bits (355), Expect = 6e-33 Identities = 102/326 (31%), Positives = 165/326 (50%), Gaps = 17/326 (5%) Query: 562 SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621 SD +++ + DVNDN PVF + Y A I E+ L G S+ ++ A+D D G N +I Y + Sbjct: 608 SDIKLIKLDISDVNDNAPVFTKSSYVAYIAENNLAGASIYRIQASDIDAGDNAKIIYSIY 667 Query: 622 PKDREEGS----FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 D E+ S F I+ +GV+ K LDRE+ + H+L A DGG P ++ T ++ I + Sbjct: 668 NTDTEDYSMSSFFSINIETGVLYAQKPLDRETQSIHELILTASDGGNPLRTGTALIRIIV 727 Query: 678 EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL 737 D ND+ PVF + ISEN+PI +++ + A D DEG NA + YSI ++N ++ Sbjct: 728 TDSNDNLPVFTQEVYKVSISENAPINSSVIILTATDKDEGTNAQITYSISKTSENNFYTS 787 Query: 738 ETRQGSDKAEL-VTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPV 793 E+ + LD E+ +K +EL++ A+ P + I+VTD NDN PV Sbjct: 788 VFNINPVMGEITIKEKPLDRET-QKDHELILTASDGGDPVKTGTAIIRIIVTDANDNLPV 846 Query: 794 MKDFQIIFNNYKDCFPV-GPFGRVPAYDAD--VTDKLQYRIL--SGNNAN--LILLNETT 846 + + + P+ V A D D ++ Y + S N+ + + +N+ Sbjct: 847 FTK-AVYKVSISENIPINSSVLHVNATDRDEGTNAQITYSFIKTSENDIHSPMFSINQIN 905 Query: 847 GSMTLSPQLNTNVPKLATMEVSVTDG 872 G + +L+ + + M V TDG Sbjct: 906 GEIKTLQKLDFELTRNYEMSVQATDG 931 >UniRef50_UPI0000F1F871 Cluster: PREDICTED: similar to FAT tumor suppressor homolog 4; n=2; Danio rerio|Rep: PREDICTED: similar to FAT tumor suppressor homolog 4 - Danio rerio Length = 2572 Score = 376 bits (926), Expect = e-102 Identities = 372/1351 (27%), Positives = 593/1351 (43%), Gaps = 145/1351 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND++P F Y E G+ V + ATD D G N ++ Y I T Sbjct: 496 IFVTDINDNAPRFSKPSYYLDYPELTEIGSIVTQVSATDPDEGFNGKIFYFIRSQT---- 551 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 E ++ R SG + V R++ +V A+D+ + + Sbjct: 552 --EYFRINSSSGEIFIKQQLRYQNSSGH-------NNINVNRHSFIVTASDRG--IKPLM 600 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA-DVGANSAIRY 189 S T T+ +N++D NDN P F +Y V + + V + K+ A D D G NS I Y Sbjct: 601 SET-TVMINVVDSNDNPPTFESPSYFTPVTKSVKVGTR--LLKVTAYDKKDFGLNSEIEY 657 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 AI GGN+ +F +D +G V++ +L + + Y L I A D G+P S+ T + I + + Sbjct: 658 AISGGNSSNKFRLDKQTGSVTVASSLAADTNKVYLLEITASDKGNPPLSDRTTVKIAVTE 717 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG--VNAELTYTMTDKDYTGNVDL 307 N + P F + +VSE + +G +I + A D D+ +N +TY ++ +GN D Sbjct: 718 ENHHTPEFSQNQVTVTVSEALTVGTAIRTLSARDKDKDKQMNGLITYNIS----SGNDDG 773 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 ++ ++G + + LD ET+ K++L V+ATDGG +++ T F Sbjct: 774 LFSVHSQTGVLSLAKTLDYETKQKHELRVSATDGGWIAKTSYVTVNIQVTDVNDNPPVFD 833 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 P +Y + E+ P GT VV + ATD D N L + + F I G +IT Sbjct: 834 PVEYFPVVQENVPSGTTVVKMNATDKDSGSNALMAYVIQSSDSDLFIIDPNTG--IITTQ 891 Query: 427 QPLDFKQERRYVLTVSATD--SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 LD++ ++ Y LTV A + R A V I + AN Y P F + Y + E AP Sbjct: 892 GFLDYEAKQVYHLTVKAFNVPDEERCSFAYVNIQLKGANEYVPRFVSKQYYFEISEAAPK 951 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 GT V V A+D D+G + + Y + F IN +TG I + LDRE Sbjct: 952 GTVVGEVFASDRDLGEDGVVYYLIFGRSRKRG-------FSINKKTGQIYVSGSLDREKE 1004 Query: 545 SGYLLTVTARDGGVPSLSDTTDV--EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 L V A++ G +D +V I+V+D ND PVF Q+LY + E G V+ Sbjct: 1005 EKISLKVLAKNAGSIRGADIDEVLVNITVLDAND-PPVFTQELYDVQVNEGLSPGGLVTF 1063 Query: 603 VGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 V A D+D V R Y + + E +F I+P +G + LDRE+V ++L +A+D Sbjct: 1064 VSAEDSDSVPSWSRFTYAI-AANHERNTFTINPQTGQVSVASELDRETVPVYNLTILAVD 1122 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY--ISENSPIGTTIGEIRAHDPDEGPN 719 G+P + + I+ + +EDIND+ P +T Y + EN GT + + + DPD PN Sbjct: 1123 SGSPAATGSAILIVTLEDINDNGPTL----VTTYGEVMENQRAGTPVMTLSSRDPDLAPN 1178 Query: 720 -AVVHYS-IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--PPLW 775 YS + G S+ F++ S EL T ++D E Y V+ S P + Sbjct: 1179 QGPFTYSLVSTGAASSYFTI-----SPTGELTTSREVDREQISDFYLSVLIKDSGIPQMS 1233 Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGN 835 + V I V D NDN + +I + + + FP G G V D D+ D Q S Sbjct: 1234 STGTVHIKVNDQNDNPSESRSVEIYVHYFGNMFPGGSLGVVKPQDPDIQDTFQ---CSLT 1290 Query: 836 NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE-IKAMMQLSVRLITEEMLLN 894 +L + TG+ L + + + V DGV+ + + +++ + N Sbjct: 1291 PPAALLFSIPTGTCDLISN-SRSTDGTFDLSVRSNDGVHSAVNSHVRVFFIGFNNATVDN 1349 Query: 895 SITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSAR 954 SI +R+ +A FLS F+ + + + I+ V + + N +F Sbjct: 1350 SILIRVTTKSASDFLSNHYLSFLRIANSQLAGLGTGVQIYGVFE-------LNNSTF--- 1399 Query: 955 RPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECL 1014 V S + +P+ + + L R + V++ D + C H PC N C Sbjct: 1400 ---LTAAVKRGHSQYVNPSGVATFFQSIKEVLHRQSGVKIDSVDHDPCSHNPCQNGGSCK 1456 Query: 1015 TVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKA------------ 1062 L G S V+ P+ + C C G+ G CET + + Sbjct: 1457 RRLGVGPEMKTEESVPVILVSNQPLQPYACNCRPGYAGALCETDIDECQPTPCHNGGTCH 1516 Query: 1063 ------SCEV-DG-DGSIC-RSGSQCVARR-EGGILCQ------GCSIDAAYTTAV---C 1103 SC DG G C R ++C++ + G LCQ C + + C Sbjct: 1517 NLVGGFSCTCPDGFTGMACERDVNECLSNPCQNGALCQNYPGGFNCLCKSGFAGVFGKHC 1576 Query: 1104 ELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYN--GRYNERHDFLALELVS 1161 EL + F S++ FP L + ++ +KFAT + LL+YN + ++ +FLALE++ Sbjct: 1577 ELNSYGFEELSYMEFPSLDPNNN-YIYIKFATLKENALLMYNHDNQTGDKAEFLALEILE 1635 Query: 1162 SEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKVLSL 1221 GR +RFSF+LG G ++ V DG +HTV ++ +D C + Sbjct: 1636 ---GR-----MRFSFNLGSGAYKLMTSIRVSDGQFHTVIARRAGMAASLTIDLCGE---- 1683 Query: 1222 AGAADFGLKYACANFTRKVLPARCEIPTETCHR--FLDL-TGPLQIGGLPNIPS----SF 1274 + P C + H LD+ L +GG+ +I + S Sbjct: 1684 -----------------EQEPGYCAVSNVAVHTDWILDVQPNRLSVGGVRSIEALLHRSG 1726 Query: 1275 QVKNKDFVGCISDFYIDHKFIDLNSYVADNG 1305 QV DFVGCI +F ++ + ++ + +A +G Sbjct: 1727 QVSTHDFVGCIMEFAVNGRPLEPSQALASHG 1757 Score = 352 bits (865), Expect = 9e-95 Identities = 250/804 (31%), Positives = 402/804 (50%), Gaps = 58/804 (7%) Query: 86 VQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145 + + F ID SG L R LD E + +Y + ++A DQ P S+ + + ++D ND Sbjct: 244 LDNAFHIDQLSGELSIRKPLDYENIEKYVLWIEARDQGFPP---YSAYEKVEIAVLDVND 300 Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205 N+P F ++ + + E++S + + A D D G N + YAII GN + F+I+ Sbjct: 301 NHPVFEQEPFHAEILENLSPQR---VLVVSALDQDSGPNGQLEYAIIDGNKENSFNINRA 357 Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265 +G++ + LD E+V Y L ++A D G P +S ++LI++ DVNDNAPRF + +F + Sbjct: 358 TGEIRTTRPLDREKVAQYSLRVKATDRGMPPKSTAVKVLISVLDVNDNAPRF-SKIFSAT 416 Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325 V EN P+G+++ RV D D G NA Y++TD LP I P +G + S L+ Sbjct: 417 VPENAPVGFTVTRVTTTDEDAGANAISRYSITD------ASLPFIIHPSTGDITISRPLN 470 Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 RE Y V+A D G + + F Y ++ E G+ V Sbjct: 471 REDTDHYIAKVSAHDSG---WTVSTDVTIFVTDINDNAPRFSKPSYYLDYPELTEIGSIV 527 Query: 386 VTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE--------R 435 ++ATD DE + ++ Y I + F I S +G I + Q L ++ Sbjct: 528 TQVSATDPDEGFNGKIFYFIR--SQTEYFRINSSSGE--IFIKQQLRYQNSSGHNNINVN 583 Query: 436 RYVLTVSATDSGGR---SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492 R+ V+A+D G + S+T V IN+ D+N+ P FE+ Y V + +GT +L V+ Sbjct: 584 RHSFIVTASDRGIKPLMSETT-VMINVVDSNDNPPTFESPSYFTPVTKSVKVGTRLLKVT 642 Query: 493 ATD-SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTV 551 A D D G+N++I Y++S + +F ++ QTG++T L +T YLL + Sbjct: 643 AYDKKDFGLNSEIEYAISG-------GNSSNKFRLDKQTGSVTVASSLAADTNKVYLLEI 695 Query: 552 TARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG 611 TA D G P LSD T V+I+V + N + P F Q T + E VGT++ + A D D Sbjct: 696 TASDKGNPPLSDRTTVKIAVTEENHHTPEFSQNQVTVTVSEALTVGTAIRTLSARDKDKD 755 Query: 612 --LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669 +NG I Y + ++G F + +GV+ K LD E+ H+L+ A DGG ++S Sbjct: 756 KQMNGLITYNIS-SGNDDGLFSVHSQTGVLSLAKTLDYETKQKHELRVSATDGGWIAKTS 814 Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729 V V+I++ D+ND+PPVF+ + EN P GTT+ ++ A D D G NA++ Y I+ Sbjct: 815 YVTVNIQVTDVNDNPPVFDPVEYFPVVQENVPSGTTVVKMNATDKDSGSNALMAYVIQ-S 873 Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP---LWNDVRVEILVTD 786 DS+ F ++ G + T LDYE+ ++ Y L ++A + P + V I + Sbjct: 874 SDSDLFIIDPNTGI----ITTQGFLDYEA-KQVYHLTVKAFNVPDEERCSFAYVNIQLKG 928 Query: 787 VNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADV-TDKLQYRILSGNNANL-ILLN 843 N+ P Q F + P G G V A D D+ D + Y ++ G + +N Sbjct: 929 ANEYVPRFVSKQYYF-EISEAAPKGTVVGEVFASDRDLGEDGVVYYLIFGRSRKRGFSIN 987 Query: 844 ETTGSMTLSPQLNTNVPKLATMEV 867 + TG + +S L+ + +++V Sbjct: 988 KKTGQIYVSGSLDREKEEKISLKV 1011 Score = 344 bits (845), Expect = 2e-92 Identities = 263/879 (29%), Positives = 419/879 (47%), Gaps = 65/879 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I VLD ND+ PVFE + + A + E S VL + A DQD G N ++EY I D Sbjct: 292 EIAVLDVNDNHPVFEQEPFHAEILENLSP-QRVLVVSALDQDSGPNGQLEYAI----IDG 346 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N E++ F I+ +G + T LDREKVA+Y++ VKATD+ P Sbjct: 347 -NKENS--------------FNINRATGEIRTTRPLDREKVAQYSLRVKATDRGMPPK-- 389 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S+ + ++++D NDN P+FS K ++ +V E+ V + ++ TD D GAN+ RY Sbjct: 390 -STAVKVLISVLDVNDNAPRFS-KIFSATVPENAPV--GFTVTRVTTTDEDAGANAISRY 445 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 +I + + F I +GD+++ + L+ E Y + A D G + +T + I + D Sbjct: 446 SIT--DASLPFIIHPSTGDITISRPLNREDTDHYIAKVSAHDSG---WTVSTDVTIFVTD 500 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY---TMTDKDYTGNVD 306 +NDNAPRF + E IG + +V A D DEG N ++ Y + T+ + Sbjct: 501 INDNAPRFSKPSYYLDYPELTEIGSIVTQVSATDPDEGFNGKIFYFIRSQTEYFRINSSS 560 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 I I + + +SG + ++ +VTA+D G P + T F Sbjct: 561 GEIFIKQQLRYQNSSGHNNINVN-RHSFIVTASDRGIKPLMSETTVMINVVDSNDNPPTF 619 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADE---DNRLHYEITGGNTRGRFSITSQNGRGLI 423 Y + + GT ++ +TA D + ++ + Y I+GGN+ +F + Q G + Sbjct: 620 ESPSYFTPVTKSVKVGTRLLKVTAYDKKDFGLNSEIEYAISGGNSSNKFRLDKQTGS--V 677 Query: 424 TVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFED 481 TVA L + Y+L ++A+D G SD V+I +T+ N++ P F T +V E Sbjct: 678 TVASSLAADTNKVYLLEITASDKGNPPLSDRTTVKIAVTEENHHTPEFSQNQVTVTVSEA 737 Query: 482 APIGTTVLVVSATDSDVG--INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 +GT + +SA D D +N ITY++SS + D F ++ QTG ++ K L Sbjct: 738 LTVGTAIRTLSARDKDKDKQMNGLITYNISS-------GNDDGLFSVHSQTGVLSLAKTL 790 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 D ET + L V+A DGG + + V I V DVNDN PVF Y + E+ GT+ Sbjct: 791 DYETKQKHELRVSATDGGWIAKTSYVTVNIQVTDVNDNPPVFDPVEYFPVVQENVPSGTT 850 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 V ++ ATD D G N + Y + D + F+IDP +G+I T LD E+ + L A Sbjct: 851 VVKMNATDKDSGSNALMAYVIQSSDSD--LFIIDPNTGIITTQGFLDYEAKQVYHLTVKA 908 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 + + S V+I+++ N+ P F S F ISE +P GT +GE+ A D D G + Sbjct: 909 FNVPDEERCSFAYVNIQLKGANEYVPRFVSKQYYFEISEAAPKGTVVGEVFASDRDLGED 968 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL----W 775 VV+Y I G FS+ + G ++ LD E K V+ + + Sbjct: 969 GVVYYLIFGRSRKRGFSINKKTG----QIYVSGSLDREKEEKISLKVLAKNAGSIRGADI 1024 Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVT---DKLQYRIL 832 ++V V I V D ND ++ + N + P G V A D+D + Y I Sbjct: 1025 DEVLVNITVLDANDPPVFTQELYDVQVN-EGLSPGGLVTFVSAEDSDSVPSWSRFTYAIA 1083 Query: 833 SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + + N +N TG ++++ +L+ + + + D Sbjct: 1084 ANHERNTFTINPQTGQVSVASELDRETVPVYNLTILAVD 1122 Score = 317 bits (778), Expect = 3e-84 Identities = 261/865 (30%), Positives = 404/865 (46%), Gaps = 80/865 (9%) Query: 28 YEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQ 87 + ++ E A +GT VL L ++D D+G N + Y+ L+ D Sbjct: 3 FHTTIPEDAPTGTDVLLLNSSDSDVGLNGVISYS--------LSGGDGQ----------- 43 Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 F I+ +G ++T + LDRE A Y +LV A+D P LSS+AT+ V + D NDN Sbjct: 44 --FSINPSTGLIITSSLLDRETRASYQLLVVASDGGQPTP--LSSSATVSVVVADINDNP 99 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 P+F Y + S + ++ + TD D G+NS + Y++ G N++ +F ID + G Sbjct: 100 PRFHHHPYVTHI--PASTSTGSLVFAVTVTDEDSGSNSQLHYSLTGRNSE-KFKIDPIRG 156 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 ++ + L ++ + +DGG+ ++++T + + D P + Sbjct: 157 AITASEKLTGSSEVTF--TVHVKDGGTNPKTDSTTVTVRFVTGGD-FPHIKLKDKAFTFP 213 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 EN P + +V G L+Y + +GN+D ID SG + LD E Sbjct: 214 ENQPTNTIVTKVTGSSPRAG---PLSYYIA----SGNLDNAFHIDQLSGELSIRKPLDYE 266 Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAED-EPPGTPVV 386 KY L + A D G PP SA F + E+ E+ P VV Sbjct: 267 NIEKYVLWIEARDQGFPPYSAYEKVEIAVLDVNDNHPVFEQEPFHAEILENLSPQRVLVV 326 Query: 387 TLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446 + D+ + +L Y I GN F+I G I +PLD ++ +Y L V ATD Sbjct: 327 SALDQDSGPNGQLEYAIIDGNKENSFNINRATGE--IRTTRPLDREKVAQYSLRVKATDR 384 Query: 447 G--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504 G +S V I++ D N+ AP F ++A+V E+AP+G TV V+ TD D G NA Sbjct: 385 GMPPKSTAVKVLISVLDVNDNAPRFSKI-FSATVPENAPVGFTVTRVTTTDEDAGANA-- 441 Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT 564 IS ++ F+I+P TG IT ++ L+RE Y+ V+A D G + + Sbjct: 442 -------ISRYSITDASLPFIIHPSTGDITISRPLNREDTDHYIAKVSAHDSG---WTVS 491 Query: 565 TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624 TDV I V D+NDN P F + Y + E +G+ V+QV ATD D G NG+I Y + + Sbjct: 492 TDVTIFVTDINDNAPRFSKPSYYLDYPELTEIGSIVTQVSATDPDEGFNGKIFYFI--RS 549 Query: 625 REEGSFVIDPASGVIRTNKAL--------DRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676 + E F I+ +SG I + L + +V H A D G P S V I Sbjct: 550 QTE-YFRINSSSGEIFIKQQLRYQNSSGHNNINVNRHSFIVTASDRGIKPLMSETTVMIN 608 Query: 677 IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD-PDEGPNAVVHYSIKGGDDSNSF 735 + D ND+PP FES ++++ +GT + ++ A+D D G N+ + Y+I GG+ SN F Sbjct: 609 VVDSNDNPPTFESPSYFTPVTKSVKVGTRLLKVTAYDKKDFGLNSEIEYAISGGNSSNKF 668 Query: 736 SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAP 792 L+ + GS VT+ K Y L I A+ +PPL + V+I VT+ N + P Sbjct: 669 RLDKQTGS-----VTVASSLAADTNKVYLLEITASDKGNPPLSDRTTVKIAVTEENHHTP 723 Query: 793 VMKDFQIIFNNYKDCFPVGPFGR-VPAYDAD----VTDKLQYRILSGNNANLILLNETTG 847 Q+ + VG R + A D D + + Y I SGN+ L ++ TG Sbjct: 724 EFSQNQVTV-TVSEALTVGTAIRTLSARDKDKDKQMNGLITYNISSGNDDGLFSVHSQTG 782 Query: 848 SMTLSPQLNTNVPKLATMEVSVTDG 872 ++L+ L+ + + VS TDG Sbjct: 783 VLSLAKTLDYETKQKHELRVSATDG 807 Score = 302 bits (741), Expect = 1e-79 Identities = 261/862 (30%), Positives = 387/862 (44%), Gaps = 88/862 (10%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72 V D ND+ P F Y + S+G+ V + TD+D G N+++ Y++ N Sbjct: 92 VADINDNPPRFHHHPYVTHIPASTSTGSLVFAVTVTDEDSGSNSQLHYSLT-----GRNS 146 Query: 73 EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132 E F+ID GA+ L +TV VK +P +D Sbjct: 147 EK---------------FKIDPIRGAITASEKLTGSSEVTFTVHVK-DGGTNPKTD---- 186 Query: 133 TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192 + T+ V + D +P K + E+ N ++ K+ + G S Y I Sbjct: 187 STTVTVRFVTGGD-FPHIKLKDKAFTFPENQPT--NTIVTKVTGSSPRAGPLS---YYIA 240 Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252 GN F ID LSG++S+ K LDYE + Y L I A+D G P S ++ I + DVND Sbjct: 241 SGNLDNAFHIDQLSGELSIRKPLDYENIEKYVLWIEARDQGFPPYSAYEKVEIAVLDVND 300 Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312 N P F F + EN+ ++ V A D D G N +L Y + D GN + I+ Sbjct: 301 NHPVFEQEPFHAEILENLS-PQRVLVVSALDQDSGPNGQLEYAIID----GNKENSFNIN 355 Query: 313 PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE 372 +G + T+ LDRE A+Y L V ATD G PP+S TA + Sbjct: 356 RATGEIRTTRPLDREKVAQYSLRVKATDRGMPPKS-TAVKVLISVLDVNDNAPRFSKIFS 414 Query: 373 VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQN-------GRGLITV 425 + E+ P G V +T TD D G N R+SIT + G IT+ Sbjct: 415 ATVPENAPVGFTVTRVTTTDED---------AGANAISRYSITDASLPFIIHPSTGDITI 465 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 ++PL+ + Y+ VSA DSG T V I +TD N+ AP F Y E IG Sbjct: 466 SRPLNREDTDHYIAKVSAHDSGWTVSTD-VTIFVTDINDNAPRFSKPSYYLDYPELTEIG 524 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 + V VSATD D G N +I Y + S+ + F IN +G I + L + S Sbjct: 525 SIVTQVSATDPDEGFNGKIFYFIRSQ---------TEYFRINSSSGEIFIKQQLRYQNSS 575 Query: 546 G--------YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 G + VTA D G+ L T V I+VVD NDN P F+ Y + + VG Sbjct: 576 GHNNINVNRHSFIVTASDRGIKPLMSETTVMINVVDSNDNPPTFESPSYFTPVTKSVKVG 635 Query: 598 TSVSQVGATD-ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 T + +V A D D GLN I Y + F +D +G + +L ++ + L+ Sbjct: 636 TRLLKVTAYDKKDFGLNSEIEYAIS-GGNSSNKFRLDKQTGSVTVASSLAADTNKVYLLE 694 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 A D G PP S V I + + N P F + +T +SE +GT I + A D D+ Sbjct: 695 ITASDKGNPPLSDRTTVKIAVTEENHHTPEFSQNQVTVTVSEALTVGTAIRTLSARDKDK 754 Query: 717 GP--NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL 774 N ++ Y+I G+D FS+ ++ G L LDYE+ ++K+EL + +A+ Sbjct: 755 DKQMNGLITYNISSGNDDGLFSVHSQTG----VLSLAKTLDYET-KQKHELRV-SATDGG 808 Query: 775 W----NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADV-TDKLQ 828 W + V V I VTDVNDN PV + F ++ P G ++ A D D ++ L Sbjct: 809 WIAKTSYVTVNIQVTDVNDNPPVFDPVE-YFPVVQENVPSGTTVVKMNATDKDSGSNALM 867 Query: 829 YRILSGNNANLILLNETTGSMT 850 ++ ++++L +++ TG +T Sbjct: 868 AYVIQSSDSDLFIIDPNTGIIT 889 Score = 285 bits (698), Expect = 2e-74 Identities = 215/732 (29%), Positives = 350/732 (47%), Gaps = 42/732 (5%) Query: 154 TYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVK 213 ++ ++ ED + T V+ + ++D+DVG N I Y++ GG+ Q FSI+ +G + Sbjct: 2 SFHTTIPED-APTGTDVLL-LNSSDSDVGLNGVISYSLSGGDGQ--FSINPSTGLIITSS 57 Query: 214 TLDYEQVRSYRLVIRAQDGGSPSR-SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI 272 LD E SY+L++ A DGG P+ S++ + + + D+NDN PRF+ + + + Sbjct: 58 LLDRETRASYQLLVVASDGGQPTPLSSSATVSVVVADINDNPPRFHHHPYVTHIPASTST 117 Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332 G + V D D G N++L Y++ TG IDP G + S +L ++ + Sbjct: 118 GSLVFAVTVTDEDSGSNSQLHYSL-----TGRNSEKFKIDPIRGAITASEKLTGSSEVTF 172 Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392 V DGG P++ + T + + E++P T +VT Sbjct: 173 --TVHVKDGGTNPKTDSTTVTVRFVTGGDFPHIKLKDK-AFTFPENQPTNT-IVTKVTGS 228 Query: 393 ADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT 452 + L Y I GN F I +G +++ +PLD++ +YVL + A D G + Sbjct: 229 SPRAGPLSYYIASGNLDNAFHIDQLSGE--LSIRKPLDYENIEKYVLWIEARDQGFPPYS 286 Query: 453 A--MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510 A V+I + D N+ PVFE P+ A + E+ VLVVSA D D G N Q+ Y++ Sbjct: 287 AYEKVEIAVLDVNDNHPVFEQEPFHAEILENLS-PQRVLVVSALDQDSGPNGQLEYAIID 345 Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570 + + F IN TG I T + LDRE ++ Y L V A D G+P S V IS Sbjct: 346 -------GNKENSFNINRATGEIRTTRPLDREKVAQYSLRVKATDRGMPPKSTAVKVLIS 398 Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630 V+DVNDN P F ++++A + E+A VG +V++V TD D G N Y + F Sbjct: 399 VLDVNDNAPRF-SKIFSATVPENAPVGFTVTRVTTTDEDAGANAISRYSITDASL---PF 454 Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690 +I P++G I ++ L+RE + K A D G + V I + DIND+ P F Sbjct: 455 IIHPSTGDITISRPLNREDTDHYIAKVSAHDSGWTVSTD---VTIFVTDINDNAPRFSKP 511 Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750 E + IG+ + ++ A DPDEG N + Y I+ + + + + K +L Sbjct: 512 SYYLDYPELTEIGSIVTQVSATDPDEGFNGKIFYFIRSQTEYFRINSSSGEIFIKQQLRY 571 Query: 751 MVDLDYESPR-KKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKD 806 + + ++ ++ A+ PL ++ V I V D NDN P + F Sbjct: 572 QNSSGHNNINVNRHSFIVTASDRGIKPLMSETTVMINVVDSNDNPPTFES-PSYFTPVTK 630 Query: 807 CFPVGP-FGRVPAYDA---DVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKL 862 VG +V AYD + +++Y I GN++N L++ TGS+T++ L + K+ Sbjct: 631 SVKVGTRLLKVTAYDKKDFGLNSEIEYAISGGNSSNKFRLDKQTGSVTVASSLAADTNKV 690 Query: 863 ATMEVSVTDGVN 874 +E++ +D N Sbjct: 691 YLLEITASDKGN 702 Score = 44.8 bits (101), Expect = 0.035 Identities = 64/250 (25%), Positives = 99/250 (39%), Gaps = 34/250 (13%) Query: 1101 AVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELV 1160 A+ + R R + L PG L+LKF T++ SG LL+ E +++ L L Sbjct: 1803 ALSQSRKRDVLLERALQGPGRSVLQHSSLELKFRTRSASGTLLHA---QESYNYTTLRL- 1858 Query: 1161 SSEAGRGGGPGLRFSFSLG-GGKSEITVEGNV-GDGSWHTVEIEYFNRTITMILDDCDKV 1218 +GG L++ G GK E TV + DG WHT+ ++ + + +D Sbjct: 1859 -----KGGL--LQYVSDAGVAGKVERTVSDVLLSDGQWHTLLLQRNGSSTVLRIDRSSSK 1911 Query: 1219 LSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKN 1278 L L DFG L + +PT H +G G VK Sbjct: 1912 LILHNTQDFG------GIDVHTL-SLGGVPTNRKHSDASSSG---FDG-----CYAYVK- 1955 Query: 1279 KDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTYICD 1338 + G + F +H+ + ++ D GC + C S+PC++G C + W TY C Sbjct: 1956 --YNGEMLPFSGEHRTVSISK--TDPSVKIGC-RGPNLCESSPCWDGLMCVNQWYTYQCV 2010 Query: 1339 CKEGHTGKDC 1348 T C Sbjct: 2011 PPGNCTSNPC 2020 Score = 43.6 bits (98), Expect = 0.080 Identities = 56/235 (23%), Positives = 85/235 (36%), Gaps = 31/235 (13%) Query: 1394 SIQLKSGLLHYSYNGETMYLPMAT-----LSDGAWHRIEIKWLGTDISVTVDYGLRTVLM 1448 +++LK GLL Y + T LSDG WH + ++ G+ + +D +++ Sbjct: 1855 TLRLKGGLLQYVSDAGVAGKVERTVSDVLLSDGQWHTLLLQRNGSSTVLRIDRSSSKLIL 1914 Query: 1449 PMLANKIQGQYIGKILIGGLDTTAGLLASDVGFFEGCIQDVR-------IGTAQSLLNRP 1501 G + + +GG+ T + F+GC V+ ++ Sbjct: 1915 HN-TQDFGGIDVHTLSLGGVPTNRKHSDASSSGFDGCYAYVKYNGEMLPFSGEHRTVSIS 1973 Query: 1502 TVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQCVSACELGPC-GAA 1560 +V+ GC+ C S C CV W + C V P C PC Sbjct: 1974 KTDPSVKIGCRGPNLCESSPCWDGLMCVNQWYTYQC------VPP---GNCTSNPCQHGG 2024 Query: 1561 RCVPDQTPKGYSCACEPGYT-------LTTSGCIESGKEECPGGWWGGSACGPCA 1608 CVP G+SC CE YT + G +C G GG C P A Sbjct: 2025 SCVPG-VRGGFSCVCEEFYTGRVCESLVACLGVRCPQGTDCKLGANGGFTCSPSA 2078 Score = 39.5 bits (88), Expect = 1.3 Identities = 14/39 (35%), Positives = 18/39 (46%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C PC+NG C +L + C C +G TG C Sbjct: 1497 CETDIDECQPTPCHNGGTCHNLVGGFSCTCPDGFTGMAC 1535 >UniRef50_A7SN97 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 850 Score = 376 bits (924), Expect = e-102 Identities = 264/798 (33%), Positives = 396/798 (49%), Gaps = 64/798 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND++PVF Y +V E + GT++L + ATD D G+NA V Y++ + L Sbjct: 102 IVVGDLNDNNPVFNPTNYSTTVFENSPVGTSLLDVTATDADSGQNAYVTYSVTAGDSHGL 161 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + V ++ G + +LDRE Y + + ATD P+S Sbjct: 162 ---------------FRAVTKVSNH-GTIEVAGNLDREVNDFYNLTITATDGGVPISR-- 203 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV--IAKIKATDADVGANSAIR 188 ++ A V I+D NDN P+FS YT S+ E+ S PV + I ATD D+ +N+ +R Sbjct: 204 TAIAIALVRILDRNDNVPKFSHARYTGSIQEN-SGPGVPVQMASSIMATDRDIESNADVR 262 Query: 189 YAIIGGNTQMQFSIDSLSG----DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 Y + G+ +QF+++ +G VS +LD+E+ +Y + A D + +++ Sbjct: 263 YRL-NGSDSIQFAVNPRTGVITTRVSPPPSLDHERTTNYTFHVIAADQAGTGHESLAEVV 321 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 I++ D NDN PRF S Q ++SE IG S+ RV A D D G+N + +++ G Sbjct: 322 IHVLDANDNTPRFIPSSIQSTISEAASIGQSVARVTANDPDSGLNGRIFFSINSGS-EGK 380 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 + I G V SG LDRE +A Y L V+A DG PR T Sbjct: 381 FE----IGRSDGVVRVSGSLDREAKAVYVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTP 436 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLIT 424 F + V+++E G+ +V TATD D+ + IT + F+I S G +T Sbjct: 437 KFTKPAFNVDVSEGVAVGSVIVNATATDPDQGSNA--AITYSMSYPGFAINSNTGS--VT 492 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 + +PLD + ++ Y TV A D GG V + I D N+ +P F Y V + P+ Sbjct: 493 ITRPLDRETKQAYSFTVHARDGGGLESNVAVNVEIGDENDNSPQFPTVQYQTDVIDRTPV 552 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE-- 542 GT VL V+A D DVG N +TY++ F+I P TG I T+ LDRE Sbjct: 553 GTIVLAVNAEDRDVGNNGHVTYAILI-----------LPFIIVPDTGNINTSSKLDREQQ 601 Query: 543 ---TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 T+ Y+L ++ D GV + + ISV D NDN+P F Q Y+A ++E+ VGT Sbjct: 602 SLYTLVHYVLNLSVTDHGVTQFTSFALLNISVTDFNDNQPQFNQSEYSATVLENMPVGTK 661 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 V+ V A D D G+N +I Y L D G F I+P++G IR KA++RE+ + + A Sbjct: 662 VTMVTARDEDSGINSQIMYSLTGGD---GVFSIEPSTGQIRLQKAINREAKENYHVTITA 718 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE-NSPIGTTIGEIRAHDPDEGP 718 D GTP SS VH+ + D+ND+PPVF S +SE N+ G + ++ A D D Sbjct: 719 SDRGTPVLSSDAKVHVHVLDVNDNPPVFTSRVYERTMSEGNAAAGEFVVQVNATDADVER 778 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLW 775 N V Y+I G F++ G + + V L+ ES + Y L++ A + P Sbjct: 779 NGHVTYTIMHG-ALGMFTINETTGVIRTQGV----LNRES-KDFYTLIVMARDQGAVPYM 832 Query: 776 NDVRVEILVTDVNDNAPV 793 + +++ V D NDN P+ Sbjct: 833 DFGTIDVHVIDKNDNTPI 850 Score = 334 bits (821), Expect = 2e-89 Identities = 266/879 (30%), Positives = 402/879 (45%), Gaps = 82/879 (9%) Query: 21 PVFEMQQYEASVREGASS-GTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXX 79 PVF Y A+ EG+S+ G + T+KATD D G N +V+Y+I V + +P Sbjct: 1 PVFTPASYNATFTEGSSTRGVLIATVKATDSDDGANGDVDYSI--VDGNVGDPRSNSD-- 56 Query: 80 XXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVN 139 F +D +G + T +L+R++ Y + + A D P S+T + + Sbjct: 57 ----------FTLDPNTGMIKTARNLERQQTFSYNLTIGAADHGLP---SFSATTRVSIV 103 Query: 140 IIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ 199 + D NDN P F+ Y+ +V E+ V + + + ATDAD G N+ + Y++ G++ Sbjct: 104 VGDLNDNNPVFNPTNYSTTVFENSPVGTS--LLDVTATDADSGQNAYVTYSVTAGDSHGL 161 Query: 200 F-SIDSLS--GDVSLVKTLDYEQVRSYRLVIRAQDGGSP-SRSNTTQLLINIRDVNDNAP 255 F ++ +S G + + LD E Y L I A DGG P SR+ L+ I D NDN P Sbjct: 162 FRAVTKVSNHGTIEVAGNLDREVNDFYNLTITATDGGVPISRTAIAIALVRILDRNDNVP 221 Query: 256 RF----YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311 +F YT QE+ VP+ + + A D D NA++ Y + D + + Sbjct: 222 KFSHARYTGSIQENSGPGVPVQMA-SSIMATDRDIESNADVRYRLNGSD-----SIQFAV 275 Query: 312 DPRSGWVYT----SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 +PR+G + T LD E Y V A D + A F+ Sbjct: 276 NPRTGVITTRVSPPPSLDHERTTNYTFHVIAADQAGTGHESLAEVVIHVLDANDNTPRFI 335 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITV 425 P + ++E G V +TA D D + R+ + I G + G+F I + G++ V Sbjct: 336 PSSIQSTISEAASIGQSVARVTANDPDSGLNGRIFFSINSG-SEGKFEIGRSD--GVVRV 392 Query: 426 AQPLDFKQERRYVLTVSATDS--GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 + LD + + YVL VSA D R V + + D N+ P F + V E Sbjct: 393 SGSLDREAKAVYVLNVSAIDGSYSPREGYGTVTVTLQDVNDNTPKFTKPAFNVDVSEGVA 452 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 +G+ ++ +ATD D G NA ITYS+S F IN TG++T + LDRET Sbjct: 453 VGSVIVNATATDPDQGSNAAITYSMSY-----------PGFAINSNTGSVTITRPLDRET 501 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 Y TV ARDGG L V + + D NDN P F Y ++++ VGT V V Sbjct: 502 KQAYSFTVHARDGG--GLESNVAVNVEIGDENDNSPQFPTVQYQTDVIDRTPVGTIVLAV 559 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI--- 660 A D DVG NG + Y + F+I P +G I T+ LDRE + + L + Sbjct: 560 NAEDRDVGNNGHVTYAILIL-----PFIIVPDTGNINTSSKLDREQQSLYTLVHYVLNLS 614 Query: 661 --DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 D G +S +++I + D ND+ P F + + EN P+GT + + A D D G Sbjct: 615 VTDHGVTQFTSFALLNISVTDFNDNQPQFNQSEYSATVLENMPVGTKVTMVTARDEDSGI 674 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLW 775 N+ + YS+ GGD FS+E G + + ++ E+ ++ Y + I A+ +P L Sbjct: 675 NSQIMYSLTGGD--GVFSIEPSTGQIRLQKA----INREA-KENYHVTITASDRGTPVLS 727 Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADV--TDKLQYRIL 832 +D +V + V DVNDN PV + G F +V A DADV + Y I+ Sbjct: 728 SDAKVHVHVLDVNDNPPVFTSRVYERTMSEGNAAAGEFVVQVNATDADVERNGHVTYTIM 787 Query: 833 SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 G + +NETTG + LN T+ V D Sbjct: 788 HG-ALGMFTINETTGVIRTQGVLNRESKDFYTLIVMARD 825 Score = 194 bits (472), Expect = 4e-47 Identities = 158/524 (30%), Positives = 237/524 (45%), Gaps = 29/524 (5%) Query: 366 FMPGQYEVELAEDEPP-GTPVVTLTATDADE--DNRLHYEITGGNT---RGRFSITSQNG 419 F P Y E G + T+ ATD+D+ + + Y I GN R T Sbjct: 3 FTPASYNATFTEGSSTRGVLIATVKATDSDDGANGDVDYSIVDGNVGDPRSNSDFTLDPN 62 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477 G+I A+ L+ +Q Y LT+ A D G S T V I + D N+ PVF Y+ + Sbjct: 63 TGMIKTARNLERQQTFSYNLTIGAADHGLPSFSATTRVSIVVGDLNDNNPVFNPTNYSTT 122 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 VFE++P+GT++L V+ATD+D G NA +TYS+++ S+ + V N T + N Sbjct: 123 VFENSPVGTSLLDVTATDADSGQNAYVTYSVTAGDSHGLFRAVTK--VSNHGTIEVAGN- 179 Query: 538 LLDRETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 LDRE Y LT+TA DGGVP S + + ++D NDN P F YT +I E++ Sbjct: 180 -LDREVNDFYNLTITATDGGVPISRTAIAIALVRILDRNDNVPKFSHARYTGSIQENSGP 238 Query: 597 GTSV---SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN----KALDRES 649 G V S + ATD D+ N + Y L+ D + F ++P +GVI T +LD E Sbjct: 239 GVPVQMASSIMATDRDIESNADVRYRLNGSDSIQ--FAVNPRTGVITTRVSPPPSLDHER 296 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 + +A D S V I + D ND+ P F + ISE + IG ++ + Sbjct: 297 TTNYTFHVIAADQAGTGHESLAEVVIHVLDANDNTPRFIPSSIQSTISEAASIGQSVARV 356 Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 A+DPD G N + +SI G + E + + +D + ++ I Sbjct: 357 TANDPDSGLNGRIFFSINSGSEGK---FEIGRSDGVVRVSGSLDREAKAVYVLNVSAIDG 413 Query: 770 ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVGPFGRVPAYDADVTDKLQ 828 + P V + + DVNDN P K + FN + + VG V A D Sbjct: 414 SYSPREGYGTVTVTLQDVNDNTP--KFTKPAFNVDVSEGVAVGSV-IVNATATDPDQGSN 470 Query: 829 YRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 I + +N TGS+T++ L+ + + V DG Sbjct: 471 AAITYSMSYPGFAINSNTGSVTITRPLDRETKQAYSFTVHARDG 514 Score = 168 bits (409), Expect = 2e-39 Identities = 134/418 (32%), Positives = 189/418 (45%), Gaps = 17/418 (4%) Query: 467 PVFENAPYTASVFEDAPI-GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525 PVF A Y A+ E + G + V ATDSD G N + YS+ N + F Sbjct: 1 PVFTPASYNATFTEGSSTRGVLIATVKATDSDDGANGDVDYSIVD--GNVGDPRSNSDFT 58 Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585 ++P TG I T + L+R+ Y LT+ A D G+PS S TT V I V D+NDN PVF Sbjct: 59 LDPNTGMIKTARNLERQQTFSYNLTIGAADHGLPSFSATTRVSIVVGDLNDNNPVFNPTN 118 Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS--GVIRTNK 643 Y+ + E++ VGTS+ V ATDAD G N + Y + D + S G I Sbjct: 119 YSTTVFENSPVGTSLLDVTATDADSGQNAYVTYSVTAGDSHGLFRAVTKVSNHGTIEVAG 178 Query: 644 ALDRESVATHDLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 LDRE ++L A DGG P +++ I ++I D ND+ P F T I ENS Sbjct: 179 NLDREVNDFYNLTITATDGGVPISRTAIAIALVRILDRNDNVPKFSHARYTGSIQENSGP 238 Query: 703 GTTI---GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759 G + I A D D NA V Y + G DS F++ R G + LD+E Sbjct: 239 GVPVQMASSIMATDRDIESNADVRYRL-NGSDSIQFAVNPRTGVITTRVSPPPSLDHERT 297 Query: 760 RKKYELVIRAASPPLWNDVRVEIL--VTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRV 816 VI A ++ E++ V D NDN P I + + +G RV Sbjct: 298 TNYTFHVIAADQAGTGHESLAEVVIHVLDANDNTPRFIP-SSIQSTISEAASIGQSVARV 356 Query: 817 PAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 A D D + ++ + I SG+ + + G + +S L+ + + VS DG Sbjct: 357 TANDPDSGLNGRIFFSINSGSEGK-FEIGRSDGVVRVSGSLDREAKAVYVLNVSAIDG 413 >UniRef50_Q7Q3K5 Cluster: ENSANGP00000007226; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000007226 - Anopheles gambiae str. PEST Length = 1645 Score = 374 bits (920), Expect = e-101 Identities = 263/814 (32%), Positives = 404/814 (49%), Gaps = 75/814 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + +LD ND+ P+F+ Y S+ E GT VL + A+D D+G N+++ Y L A+T Sbjct: 3 VTILDVNDNPPIFDHSDYIVSLNESVLPGTPVLQVMASDSDLGDNSKITYY--LADAETQ 60 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F +D +G + TR +LDRE VA YT++V A D SP Sbjct: 61 -------------------FTVDPETG-IATRRALDRELVAAYTLVVIARDHGSPPQ--- 97 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SS+AT+ V + D NDN P+ + + V V ED + +IA++ ATD D G N+ ++Y Sbjct: 98 SSSATVSVAVEDANDNSPELYPRAFFVPVAED--APEGTLIAQLTATDRDEGENAIVQYE 155 Query: 191 IIGGNT--QMQFSIDSLSGDVSLVKTLDYEQVRSYR------LVIRAQDGGSPSRSNTTQ 242 ++GG T F+ID+ +G ++L +L +R L + A DGGSP + T Sbjct: 156 LVGGPTTDAALFAIDATTGALTLRSSLQKSPKPVHRPGTVLSLEVSATDGGSPPLTTRTT 215 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 + + + DVND+ P F + ++ S+ E++P+ + A DAD G N ++Y + + + Sbjct: 216 VQVTVEDVNDHTPVFDHTSYETSLLESMPVNSRFFALAASDADVGPNGRISYAIVEGN-- 273 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRET---QAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 + + +ID R+G++ T DRE Q+ L T +D G Sbjct: 274 -DREEDFSIDSRNGFIRTRRSFDREALGGQSFLALEATVSDNGAVRLRDRVKIKVFITDV 332 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQ 417 F+ Y V+++E GT +V + DADE + + Y I+ GN RF+I Sbjct: 333 NDNAPVFVRAPYRVQISEGASIGTQLVRVYTHDADEGLNGDVFYYISEGNRAERFAIDDS 392 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGR---SDTAMVQINITDANNYAPVFENAPY 474 G+ IT+A+ LD + Y LTV A D+ + S + V I + D N+ AP F Sbjct: 393 TGQ--ITLARALDRETTASYRLTVVAHDASKQHRLSASTTVTIEVLDENDDAPEFTQTLS 450 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 ++ E PIGT ++ ATD D+G NAQI +S+ A + F I+ +GA+ Sbjct: 451 QIAIVETTPIGTELMRFRATDLDLGANAQIAFSI-------AAGNRRDTFHIDALSGALY 503 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 ++ LD E Y L ++A DGG P L+ T ++V+D NDN P F I E Sbjct: 504 LHRALDYEDTQSYSLNISAADGGNPRLATTILFAVNVIDANDNPPAFPNTAIVRQIREGI 563 Query: 595 LVGTSVSQVGATDADVGLNGRIHYEL---DPKDRE-EGSFVIDPASGVIRTNKALDRESV 650 + T + V A D D GLNG++ YE+ DP+D + E F I+P +GVI T +DRE++ Sbjct: 564 PLNTPIVTVTAEDPDSGLNGKVRYEIAHQDPQDGDGERHFGINPTTGVIHTLHLIDREAI 623 Query: 651 ATHDLKAVAIDGGTPPQSS-------TVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703 T+ L +A D PP TVI+ + + D NDSPP F++ L F +SE+ +G Sbjct: 624 DTYRLTVLATDQAAPPAQRLSAEKLVTVIIRVNVLDKNDSPPKFQNLPLVFSVSEDLAVG 683 Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKK 762 T+ I A DPD + Y++ GD F+LE G L+ + D LD E+ Sbjct: 684 QTVARITATDPD--TLGKLEYALLDGDAPKKFALERETG-----LLKLRDTLDRET-EDS 735 Query: 763 YELVIRAASPPLWNDVRVEILVTDVNDNAPVMKD 796 Y L + + + I +TD NDN PV + Sbjct: 736 YRLKVSVTDGIQSTETTITIQITDTNDNPPVFAE 769 Score = 356 bits (876), Expect = 4e-96 Identities = 244/776 (31%), Positives = 375/776 (48%), Gaps = 46/776 (5%) Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195 ++V I+D NDN P F Y VS++E + + PV+ ++ A+D+D+G NS I Y + Sbjct: 1 VNVTILDVNDNPPIFDHSDYIVSLNESV-LPGTPVL-QVMASDSDLGDNSKITYYLADAE 58 Query: 196 TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP 255 TQ F++D +G ++ + LD E V +Y LV+ A+D GSP +S++ + + + D NDN+P Sbjct: 59 TQ--FTVDPETG-IATRRALDRELVAAYTLVVIARDHGSPPQSSSATVSVAVEDANDNSP 115 Query: 256 RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315 Y F V+E+ P G I ++ A D DEG NA + Y + T ID + Sbjct: 116 ELYPRAFFVPVAEDAPEGTLIAQLTATDRDEGENAIVQYELVGGPTTDAA--LFAIDATT 173 Query: 316 GWVYTSGQLDRETQAKYQ------LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 G + L + + ++ L V+ATDGG PP + T F Sbjct: 174 GALTLRSSLQKSPKPVHRPGTVLSLEVSATDGGSPPLTTRTTVQVTVEDVNDHTPVFDHT 233 Query: 370 QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGR-FSITSQNGRGLITVA 426 YE L E P + L A+DAD + R+ Y I GN R FSI S+N G I Sbjct: 234 SYETSLLESMPVNSRFFALAASDADVGPNGRISYAIVEGNDREEDFSIDSRN--GFIRTR 291 Query: 427 QPLDFKQ---ERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFED 481 + D + + L + +D+G D +++ ITD N+ APVF APY + E Sbjct: 292 RSFDREALGGQSFLALEATVSDNGAVRLRDRVKIKVFITDVNDNAPVFVRAPYRVQISEG 351 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 A IGT ++ V D+D G+N + Y +S N A ++F I+ TG IT + LDR Sbjct: 352 ASIGTQLVRVYTHDADEGLNGDVFYYISE--GNRA-----ERFAIDDSTGQITLARALDR 404 Query: 542 ETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 ET + Y LTV A D LS +T V I V+D ND+ P F Q L I+E +GT + Sbjct: 405 ETTASYRLTVVAHDASKQHRLSASTTVTIEVLDENDDAPEFTQTLSQIAIVETTPIGTEL 464 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 + ATD D+G N +I + + +R + +F ID SG + ++ALD E ++ L A Sbjct: 465 MRFRATDLDLGANAQIAFSIAAGNRRD-TFHIDALSGALYLHRALDYEDTQSYSLNISAA 523 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 DGG P ++T++ + + D ND+PP F + + I E P+ T I + A DPD G N Sbjct: 524 DGGNPRLATTILFAVNVIDANDNPPAFPNTAIVRQIREGIPLNTPIVTVTAEDPDSGLNG 583 Query: 721 VVHYSI-----KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW 775 V Y I + GD F + G + ++D + + L A+PP Sbjct: 584 KVRYEIAHQDPQDGDGERHFGINPTTG--VIHTLHLIDREAIDTYRLTVLATDQAAPPAQ 641 Query: 776 N-------DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQ 828 V + + V D ND+ P ++ ++F+ +D R+ A D D KL+ Sbjct: 642 RLSAEKLVTVIIRVNVLDKNDSPPKFQNLPLVFSVSEDLAVGQTVARITATDPDTLGKLE 701 Query: 829 YRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884 Y +L G+ L TG + L L+ ++VSVTDG+ + + + + Sbjct: 702 YALLDGDAPKKFALERETGLLKLRDTLDRETEDSYRLKVSVTDGIQSTETTITIQI 757 Score = 326 bits (800), Expect = 7e-87 Identities = 249/810 (30%), Positives = 370/810 (45%), Gaps = 66/810 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 Q+ V D NDH+PVF+ YE S+ E + L A+D D+G N + Y I Sbjct: 217 QVTVEDVNDHTPVFDHTSYETSLLESMPVNSRFFALAASDADVGPNGRISYAI------- 269 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + D ++ F ID R+G + TR S DRE + + L + + R Sbjct: 270 VEGNDR-----------EEDFSIDSRNGFIRTRRSFDREALGGQSFLALEATVSDNGAVR 318 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L I V I D NDN P F Y V + E S+ + ++ DAD G N + Y Sbjct: 319 LRDRVKIKVFITDVNDNAPVFVRAPYRVQISEGASI--GTQLVRVYTHDADEGLNGDVFY 376 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR-SNTTQLLINIR 248 I GN +F+ID +G ++L + LD E SYRL + A D R S +T + I + Sbjct: 377 YISEGNRAERFAIDDSTGQITLARALDRETTASYRLTVVAHDASKQHRLSASTTVTIEVL 436 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D ND+AP F +L Q ++ E PIG ++R +A D D G NA++ +++ GN Sbjct: 437 DENDDAPEFTQTLSQIAIVETTPIGTELMRFRATDLDLGANAQIAFSIA----AGNRRDT 492 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 ID SG +Y LD E Y L ++A DGG+P + T F Sbjct: 493 FHIDALSGALYLHRALDYEDTQSYSLNISAADGGNPRLATTILFAVNVIDANDNPPAFPN 552 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEIT-----GGNTRGRFSITSQNGRG 421 ++ E P TP+VT+TA D D + ++ YEI G+ F I G Sbjct: 553 TAIVRQIREGIPLNTPIVTVTAEDPDSGLNGKVRYEIAHQDPQDGDGERHFGINPTT--G 610 Query: 422 LITVAQPLDFKQERRYVLTVSATD---------SGGRSDTAMVQINITDANNYAPVFENA 472 +I +D + Y LTV ATD S + T ++++N+ D N+ P F+N Sbjct: 611 VIHTLHLIDREAIDTYRLTVLATDQAAPPAQRLSAEKLVTVIIRVNVLDKNDSPPKFQNL 670 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 P SV ED +G TV ++ATD D ++ Y+L + +A ++F + +TG Sbjct: 671 PLVFSVSEDLAVGQTVARITATDPDT--LGKLEYAL---LDGDA----PKKFALERETGL 721 Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592 + LDRET Y L V+ DG S T + I + D NDN PVF + Y+ +I E Sbjct: 722 LKLRDTLDRETEDSYRLKVSVTDG---IQSTETTITIQITDTNDNPPVFAEPAYSFDIPE 778 Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS---FVIDPASGVIRTNKALDRES 649 +A G V + ATD D + Y + + + + F +D +SG I T LD E Sbjct: 779 NAQRGFHVGVIAATDPDNVIPPNNGYVITVRAYDADTPPRFRLDASSGEITTAAVLDCED 838 Query: 650 VATHDLKAVAIDGG-TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 + + +A D T P+++ V + I ++D+ND+ P F + + + G + Sbjct: 839 MPIYHFTLMAQDSSTTEPRATLVNLTIDVQDVNDNSPAFGAPTFHVNVPDRIKPGQFVFG 898 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLET---RQGSDKAELVTMVDLDYESPRKKYEL 765 +A D DEG NA + YSI G + L T +D E+ T LD E +Y L Sbjct: 899 AKAIDRDEGVNARLLYSIHTGVIEAATELSTPIFEINTDTGEIYTTTRLDRED-IAQYTL 957 Query: 766 VIRAAS---PPLWNDVRVEILVTDVNDNAP 792 ++ A P L V + V D NDN P Sbjct: 958 IVEAVDQGVPQLTGSATVLVNVLDKNDNPP 987 Score = 324 bits (796), Expect = 2e-86 Identities = 275/953 (28%), Positives = 423/953 (44%), Gaps = 57/953 (5%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NV+D ND+ P F +REG T ++T+ A D D G N +V Y E+ D Sbjct: 538 VNVIDANDNPPAFPNTAIVRQIREGIPLNTPIVTVTAEDPDSGLNGKVRY--EIAHQD-- 593 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P+D F I+ +G + T +DRE + Y + V ATDQA+P + RL Sbjct: 594 -PQDGDGERH---------FGINPTTGVIHTLHLIDREAIDTYRLTVLATDQAAPPAQRL 643 Query: 131 SS----TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 S+ T I VN++D ND+ P+F SV ED++V +A+I ATD D Sbjct: 644 SAEKLVTVIIRVNVLDKNDSPPKFQNLPLVFSVSEDLAV--GQTVARITATDPDTLGK-- 699 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 + YA++ G+ +F+++ +G + L TLD E SYRL + DG +S T + I Sbjct: 700 LEYALLDGDAPKKFALERETGLLKLRDTLDRETEDSYRLKVSVTDG---IQSTETTITIQ 756 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 I D NDN P F + + EN G+ + + A D D + Y +T + Y + Sbjct: 757 ITDTNDNPPVFAEPAYSFDIPENAQRGFHVGVIAATDPDNVIPPNNGYVITVRAYDADTP 816 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSATATXXXXXXXXXXXXXX 365 +D SG + T+ LD E Y + A D PR+ Sbjct: 817 PRFRLDASSGEITTAAVLDCEDMPIYHFTLMAQDSSTTEPRATLVNLTIDVQDVNDNSPA 876 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITS-----QN 418 F + V + + PG V A D DE + RL Y I G +++ Sbjct: 877 FGAPTFHVNVPDRIKPGQFVFGAKAIDRDEGVNARLLYSIHTGVIEAATELSTPIFEINT 936 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTA 476 G I LD + +Y L V A D G + +A V +N+ D N+ P F Sbjct: 937 DTGEIYTTTRLDREDIAQYTLIVEAVDQGVPQLTGSATVLVNVLDKNDNPPKFTRLFSDE 996 Query: 477 SVFEDAPIG---TTVLVVSATDSDVGINA----QITYSLSSEISNEAVAHHDQQFVINPQ 529 + + A + T ++ T D NA YS + ++V + F++N Sbjct: 997 YILKVAAVDGAWRTETPLTITIQDQNDNAPEFEHSYYSFNFRELQKSVTFRND-FMVNSV 1055 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGV-PSLSDT-TDVEISVVDVNDNEPVFKQQLYT 587 TGA++ LD + + Y L +TA D G P S + IS+ D ND P F++ LY Sbjct: 1056 TGAVSIRNPLDYDLIQVYQLNITAEDLGYKPKRSIAMAQIIISIQDGND-PPEFQRDLYE 1114 Query: 588 ANIMEDALVGTSVSQVGATDADVG-LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646 A++ E +GT V V A D DV N + + + + + SF IDP SG I T + LD Sbjct: 1115 ASVSEGDPIGTKVIVVKAVDKDVRPQNNQFSFSIIGGNNDH-SFKIDPQSGQIETARKLD 1173 Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706 RE+V TH L AID GTPPQ+ T +V I + DIND+ P F+ + EN P T + Sbjct: 1174 RETVPTHKLLLGAIDTGTPPQTGTTVVRITVTDINDNGPTFDPKDTIGAVLENEPPNTVV 1233 Query: 707 GEIRAHDPDEGPN-AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPRKKYE 764 + A DPD PN A Y + GG + F+LE G L T+ LD E +P+ + Sbjct: 1234 MTLAATDPDLPPNGAPFTYQLVGGRHKSLFTLERHSG----VLKTVRSLDREQTPQLELL 1289 Query: 765 LVIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV 823 +V+ P + + V D ND+ ++ ++ +++ G V D DV Sbjct: 1290 VVVEDNGKPRKRTQHTITVNVLDQNDSPSTPRNVHVLVYAFREGPLHGDIASVHPNDPDV 1349 Query: 824 TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLA-TMEVSVTDGVN-EIKAMMQ 881 T + ++L+ N + + L +P T VS DG + ++ + + Sbjct: 1350 TGDYRCKLLTDTNKQPVTTFTISSGCQLRLTNANRIPTSGHTFLVSGNDGKHPDVTSTVS 1409 Query: 882 LSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIF 934 + + SITVRL ++++ FL+ F+D + A + + I F Sbjct: 1410 VEFLHFDNATVDQSITVRLENISSANFLANYYRNFVDIVKASLEPADDLILCF 1462 Score = 314 bits (770), Expect = 3e-83 Identities = 249/879 (28%), Positives = 405/879 (46%), Gaps = 63/879 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ + D ND++PVF Y + EGAS GT ++ + D D G N +V Y I Sbjct: 326 KVFITDVNDNAPVFVRAPYRVQISEGASIGTQLVRVYTHDADEGLNGDVFYYIS------ 379 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + F ID +G + +LDRE A Y + V A D + R Sbjct: 380 -------------EGNRAERFAIDDSTGQITLARALDRETTASYRLTVVAHDASK--QHR 424 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LS++ T+ + ++D+ND+ P+F++ +++ E + + + +ATD D+GAN+ I + Sbjct: 425 LSASTTVTIEVLDENDDAPEFTQTLSQIAIVETTPIGTE--LMRFRATDLDLGANAQIAF 482 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 +I GN + F ID+LSG + L + LDYE +SY L I A DGG+P + T +N+ D Sbjct: 483 SIAAGNRRDTFHIDALSGALYLHRALDYEDTQSYSLNISAADGGNPRLATTILFAVNVID 542 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD-YTGNVDLP 308 NDN P F + + E +P+ IV V A D D G+N ++ Y + +D G+ + Sbjct: 543 ANDNPPAFPNTAIVRQIREGIPLNTPIVTVTAEDPDSGLNGKVRYEIAHQDPQDGDGERH 602 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXXXXF 366 I+P +G ++T +DRE Y+L V ATD PP R + Sbjct: 603 FGINPTTGVIHTLHLIDREAIDTYRLTVLATDQAAPPAQRLSAEKLVTVIIRVNVLDKND 662 Query: 367 MPGQYE-----VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421 P +++ ++ED G V +TATD D +L Y + G+ +F++ + G Sbjct: 663 SPPKFQNLPLVFSVSEDLAVGQTVARITATDPDTLGKLEYALLDGDAPKKFALERET--G 720 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 L+ + LD + E Y L VS TD G +S + I ITD N+ PVF Y+ + E+ Sbjct: 721 LLKLRDTLDRETEDSYRLKVSVTD-GIQSTETTITIQITDTNDNPPVFAEPAYSFDIPEN 779 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 A G V V++ATD D I Y ++ + A +F ++ +G ITT +LD Sbjct: 780 AQRGFHVGVIAATDPDNVIPPNNGYVITVRAYD---ADTPPRFRLDASSGEITTAAVLDC 836 Query: 542 ETMSGYLLTVTARDGGVPSLSDT-TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 E M Y T+ A+D T ++ I V DVNDN P F + N+ + G V Sbjct: 837 EDMPIYHFTLMAQDSSTTEPRATLVNLTIDVQDVNDNSPAFGAPTFHVNVPDRIKPGQFV 896 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGS------FVIDPASGVIRTNKALDRESVATHD 654 A D D G+N R+ Y + E + F I+ +G I T LDRE +A + Sbjct: 897 FGAKAIDRDEGVNARLLYSIHTGVIEAATELSTPIFEINTDTGEIYTTTRLDREDIAQYT 956 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE----------NSPIGT 704 L A+D G P + + V + + D ND+PP F YI + +P+ Sbjct: 957 LIVEAVDQGVPQLTGSATVLVNVLDKNDNPPKFTRLFSDEYILKVAAVDGAWRTETPLTI 1016 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764 TI + + P E ++ ++ + S +F + S + LDY+ + Y+ Sbjct: 1017 TIQDQNDNAP-EFEHSYYSFNFRELQKSVTFRNDFMVNSVTGAVSIRNPLDYDL-IQVYQ 1074 Query: 765 LVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYD 820 L I A P + +I+++ + N P + + + P+G V A D Sbjct: 1075 LNITAEDLGYKPKRSIAMAQIIISIQDGNDPPEFQRDLYEASVSEGDPIGTKVIVVKAVD 1134 Query: 821 ADV---TDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 DV ++ + I+ GNN + ++ +G + + +L+ Sbjct: 1135 KDVRPQNNQFSFSIIGGNNDHSFKIDPQSGQIETARKLD 1173 Score = 207 bits (506), Expect = 3e-51 Identities = 174/607 (28%), Positives = 279/607 (45%), Gaps = 52/607 (8%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 ++ I+V D ND+SP F + +V + G V KA D+D G NA + Y+I Sbjct: 861 VNLTIDVQDVNDNSPAFGAPTFHVNVPDRIKPGQFVFGAKAIDRDEGVNARLLYSIHTGV 920 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 + +F I+ +G + T LDRE +A+YT++V+A DQ P Sbjct: 921 IE------------AATELSTPIFEINTDTGEIYTTTRLDREDIAQYTLIVEAVDQGVP- 967 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFS-----EKTYTVSVDEDISVTDNPVIAKIKATDADV 181 +L+ +AT+ VN++D NDN P+F+ E V+ + T+ P+ I+ + + Sbjct: 968 --QLTGSATVLVNVLDKNDNPPKFTRLFSDEYILKVAAVDGAWRTETPLTITIQDQNDNA 1025 Query: 182 GANSAIRYAIIGGNTQM------QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD-GGS 234 Y+ Q F ++S++G VS+ LDY+ ++ Y+L I A+D G Sbjct: 1026 PEFEHSYYSFNFRELQKSVTFRNDFMVNSVTGAVSIRNPLDYDLIQVYQLNITAEDLGYK 1085 Query: 235 PSRS-NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAEL 292 P RS Q++I+I+D ND P F L++ SVSE PIG ++ V+A D D N + Sbjct: 1086 PKRSIAMAQIIISIQDGND-PPEFQRDLYEASVSEGDPIGTKVIVVKAVDKDVRPQNNQF 1144 Query: 293 TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352 ++++ GN D IDP+SG + T+ +LDRET ++LL+ A D G PP++ T Sbjct: 1145 SFSIIG----GNNDHSFKIDPQSGQIETARKLDRETVPTHKLLLGAIDTGTPPQTGTTVV 1200 Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTR 409 F P + E+EPP T V+TL ATD D Y++ GG + Sbjct: 1201 RITVTDINDNGPTFDPKDTIGAVLENEPPNTVVMTLAATDPDLPPNGAPFTYQLVGGRHK 1260 Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG-GRSDTA-MVQINITDANNYAP 467 F T + G++ + LD +Q + L V D+G R T + +N+ D N+ Sbjct: 1261 SLF--TLERHSGVLKTVRSLDREQTPQLELLVVVEDNGKPRKRTQHTITVNVLDQNDSPS 1318 Query: 468 VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527 N F + P+ + V D DV L ++ + + V F I+ Sbjct: 1319 TPRNVHVLVYAFREGPLHGDIASVHPNDPDV--TGDYRCKLLTDTNKQPVT----TFTIS 1372 Query: 528 PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD---VNDNEPVFKQQ 584 TN +R SG+ V+ DG P ++ T VE D V+ + V + Sbjct: 1373 SGCQLRLTN--ANRIPTSGHTFLVSGNDGKHPDVTSTVSVEFLHFDNATVDQSITVRLEN 1430 Query: 585 LYTANIM 591 + +AN + Sbjct: 1431 ISSANFL 1437 >UniRef50_Q4S3T8 Cluster: Chromosome 20 SCAF14744, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 20 SCAF14744, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 2413 Score = 373 bits (918), Expect = e-101 Identities = 264/795 (33%), Positives = 388/795 (48%), Gaps = 46/795 (5%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I VLD ND+SPVF S +E ASSG V+ ATD DIG N T +V Sbjct: 107 RIVVLDINDNSPVFPDASIVVSFKEDASSGRQVILDTATDTDIGSNGVDHTTYRIVKG-- 164 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N + + F L++ LDRE Y +L++ D+ P + Sbjct: 165 -NEQRKFRLDITVNPSGEGAFL------HLVSTGGLDREVTPFYQLLIEVEDKGEP---K 214 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 ++V I D NDN P F Y SV ED +V + I ++ A+D D AN+ IRY Sbjct: 215 TFGYLQVNVTIQDINDNPPSFERDLYQASVLEDAAVGSS--ILQVTASDGDEAANAEIRY 272 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 + + + F ID +G + + + LDYE R Y L I A D G PS S + I + D Sbjct: 273 FL---DEETPFQIDPKTGTIIIKEGLDYESRREYSLTIHAVDNGVPSLSGRAEATIKLLD 329 Query: 250 VNDNAP----RFY--TSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYT 302 VNDN P R++ TS F SV EN +G + + D+D N ++ ++ + Sbjct: 330 VNDNDPVVKFRYFPTTSKF-ASVDENAQVGTVVALLTVSDSDSSAANGNISVSILGGNEQ 388 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSATATXXXXXXXXXX 361 + ++ + P + + LDRE + Y L V+ +D G P RS+ A+ Sbjct: 389 RHFEVHTSPVPNLSLIKVASVLDRERISSYNLTVSVSDNGKPVARSSFASLVIFVNDIND 448 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419 F +Y V+++ED P G+ + ++ATD D ++ L Y + GN G FSI S+N Sbjct: 449 HPPIFQETEYRVDISEDIPKGSYIKGVSATDGDSGQNANLRYSLVSGNALGWFSI-SENS 507 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477 GL+T A LD + VL +SA D G R + INITD N+ P F + + S Sbjct: 508 -GLVTSAALLDREATSEVVLNISAKDQGLQPRISYTKLIINITDVNDQVPTFTQSTFHVS 566 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 + E AP GT +LV+SATD D+G N + +S +E A +F ++P +G ++T Sbjct: 567 LAEHAPAGTQLLVLSATDGDLGPNGTMRFSFDAETPAAA----QGRFRLDPLSGRLSTAV 622 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LDRE + YLL V DGG P L V +++ DVNDN PVF Y AN+ E+ G Sbjct: 623 ELDREEQASYLLHVQVTDGGSPPLRSAGKVNVTLRDVNDNRPVFYPLQYFANVKENEPSG 682 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 + V+ V ATD D+G NG + Y + D +F I+ +G I T LDRE T+ L+ Sbjct: 683 SYVTTVSATDPDLGRNGTVKYMITAGD--AATFHINGNTGKISTLVPLDREEKTTYQLQV 740 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A DG + IV + + D D+PPVF +F + EN +GT +G + A D Sbjct: 741 TAADGSGLRSHTPAIVTVSVLDTQDNPPVFSQKGYSFVMFENVGVGTVVGTVSATTVDLN 800 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND 777 N V Y I GD F++ + ++ +D E + ++L + A + + + Sbjct: 801 TN--VSYLITSGDQRGLFAV-----NSAGQITASSPIDREE-QSFHQLKVVARAGQITGE 852 Query: 778 VRVEILVTDVNDNAP 792 V V I V D+NDNAP Sbjct: 853 VSVNITVKDLNDNAP 867 Score = 355 bits (873), Expect = 1e-95 Identities = 263/858 (30%), Positives = 408/858 (47%), Gaps = 56/858 (6%) Query: 11 INVLDCNDHSPVFEMQQYE-----ASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELV 65 I +LD ND+ PV + + + ASV E A GT V L +D D A ++ ++ Sbjct: 325 IKLLDVNDNDPVVKFRYFPTTSKFASVDENAQVGTVVALLTVSDSD-SSAANGNISVSIL 383 Query: 66 TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125 + + ++ + LDRE+++ Y + V +D P Sbjct: 384 GGNEQRHFEVHTSPVPNLSLIK-------------VASVLDRERISSYNLTVSVSDNGKP 430 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 V+ SS A++ + + D ND+ P F E Y V + EDI I + ATD D G N+ Sbjct: 431 VAR--SSFASLVIFVNDINDHPPIFQETEYRVDISEDIP--KGSYIKGVSATDGDSGQNA 486 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 +RY+++ GN FSI SG V+ LD E L I A+D G R + T+L+I Sbjct: 487 NLRYSLVSGNALGWFSISENSGLVTSAALLDREATSEVVLNISAKDQGLQPRISYTKLII 546 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 NI DVND P F S F S++E+ P G ++ + A D D G N + ++ D + Sbjct: 547 NITDVNDQVPTFTQSTFHVSLAEHAPAGTQLLVLSATDGDLGPNGTMRFSF-DAETPAAA 605 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 +DP SG + T+ +LDRE QA Y L V TDGG PP + Sbjct: 606 QGRFRLDPLSGRLSTAVELDREEQASYLLHVQVTDGGSPPLRSAGKVNVTLRDVNDNRPV 665 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLI 423 F P QY + E+EP G+ V T++ATD D + + Y IT G+ F I G+ I Sbjct: 666 FYPLQYFANVKENEPSGSYVTTVSATDPDLGRNGTVKYMITAGDA-ATFHINGNTGK--I 722 Query: 424 TVAQPLDFKQERRYVLTVSATD-SGGRSDT-AMVQINITDANNYAPVFENAPYTASVFED 481 + PLD +++ Y L V+A D SG RS T A+V +++ D + PVF Y+ +FE+ Sbjct: 723 STLVPLDREEKTTYQLQVTAADGSGLRSHTPAIVTVSVLDTQDNPPVFSQKGYSFVMFEN 782 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 +GT V VSAT D +N ++Y ++S F +N G IT + +DR Sbjct: 783 VGVGTVVGTVSATTVD--LNTNVSYLITS-------GDQRGLFAVN-SAGQITASSPIDR 832 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 E S + L V AR G ++ V I+V D+NDN P F + + +E+ G ++ Sbjct: 833 EEQSFHQLKVVARAG---QITGEVSVNITVKDLNDNAPRFIHAVEHVSAVENWSTGHTIF 889 Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 Q A+D D G NG + Y L K G F I G+I L+ + ++++++ +A D Sbjct: 890 QAKASDPDEGANGVVVYSL--KQNPRGLFHIHEKHGLITLTGPLE-VTASSYEVEVIAED 946 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 G P +S++++ + + D+ND+ PVF+ I E+ P+ + ++ A D D G N Sbjct: 947 MGVPKHTSSLVLIVSVYDVNDNSPVFDQLSYEVLIPESEPVNSRFFKVEATDKDSGFNGE 1006 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDV 778 + Y I GG+ + F + +L +LD E +++Y LV+ A A PL V Sbjct: 1007 IVYDIAGGNTGDVFGI-----FPDGQLYIKAELDREI-QERYNLVLVARDRAVEPLSASV 1060 Query: 779 RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNAN 838 V +++ DVNDN P+ +F+ ++ GRV A D D + R Sbjct: 1061 NVSVILDDVNDNRPLFNSTNYVFHFEEEQQRGSLVGRVFAEDKDFGPNSEVRYTFEMPQP 1120 Query: 839 LILLNETTGSMTLSPQLN 856 LN TG ++ + Q + Sbjct: 1121 NFELNAITGELSSTAQFD 1138 Score = 354 bits (871), Expect = 2e-95 Identities = 258/812 (31%), Positives = 391/812 (48%), Gaps = 57/812 (7%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +F I+G SG + T A +DRE + + V +S + + + + ++D NDN P Sbjct: 65 LFSINGSSGVISTSAVIDREALQSDVINVVV------LSSQPTYPTEVRIVVLDINDNSP 118 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA--IRYAIIGGNTQMQFSID--- 203 F + + VS ED S + VI ATD D+G+N Y I+ GN Q +F +D Sbjct: 119 VFPDASIVVSFKEDAS-SGRQVILDT-ATDTDIGSNGVDHTTYRIVKGNEQRKFRLDITV 176 Query: 204 SLSGD---VSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY 258 + SG+ + LV T LD E Y+L+I +D G P Q+ + I+D+NDN P F Sbjct: 177 NPSGEGAFLHLVSTGGLDREVTPFYQLLIEVEDKGEPKTFGYLQVNVTIQDINDNPPSFE 236 Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV 318 L+Q SV E+ +G SI++V A D DE NAE+ Y + + + P IDP++G + Sbjct: 237 RDLYQASVLEDAAVGSSILQVTASDGDEAANAEIRYFLDE-------ETPFQIDPKTGTI 289 Query: 319 YTSGQLDRETQAKYQLLVTATDGGDPPRS----ATATXXXXXXXXXXXXXXFMPGQYE-V 373 LD E++ +Y L + A D G P S AT + P + Sbjct: 290 IIKEGLDYESRREYSLTIHAVDNGVPSLSGRAEATIKLLDVNDNDPVVKFRYFPTTSKFA 349 Query: 374 ELAEDEPPGTPVVTLTATDADE---DNRLHYEITGGNTRGRFSITSQ--NGRGLITVAQP 428 + E+ GT V LT +D+D + + I GGN + F + + LI VA Sbjct: 350 SVDENAQVGTVVALLTVSDSDSSAANGNISVSILGGNEQRHFEVHTSPVPNLSLIKVASV 409 Query: 429 LDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 LD ++ Y LTVS +D+G RS A + I + D N++ P+F+ Y + ED P G Sbjct: 410 LDRERISSYNLTVSVSDNGKPVARSSFASLVIFVNDINDHPPIFQETEYRVDISEDIPKG 469 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 + + VSATD D G NA + YSL +S A+ F I+ +G +T+ LLDRE S Sbjct: 470 SYIKGVSATDGDSGQNANLRYSL---VSGNALG----WFSISENSGLVTSAALLDREATS 522 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 +L ++A+D G+ T + I++ DVND P F Q + ++ E A GT + + A Sbjct: 523 EVVLNISAKDQGLQPRISYTKLIINITDVNDQVPTFTQSTFHVSLAEHAPAGTQLLVLSA 582 Query: 606 TDADVGLNGRIHYELDPKD--REEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 TD D+G NG + + D + +G F +DP SG + T LDRE A++ L DGG Sbjct: 583 TDGDLGPNGTMRFSFDAETPAAAQGRFRLDPLSGRLSTAVELDREEQASYLLHVQVTDGG 642 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 +PP S V++ + D+ND+ PVF + EN P G+ + + A DPD G N V Sbjct: 643 SPPLRSAGKVNVTLRDVNDNRPVFYPLQYFANVKENEPSGSYVTTVSATDPDLGRNGTVK 702 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP---LWNDVRV 780 Y I G D+ +F + G ++ T+V LD E + Y+L + AA V Sbjct: 703 YMITAG-DAATFHINGNTG----KISTLVPLDREE-KTTYQLQVTAADGSGLRSHTPAIV 756 Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLI 840 + V D DN PV F +++ G V A D+ + Y I SG+ L Sbjct: 757 TVSVLDTQDNPPVFSQKGYSFVMFENVGVGTVVGTVSATTVDLNTNVSYLITSGDQRGLF 816 Query: 841 LLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 +N + G +T S ++ ++V G Sbjct: 817 AVN-SAGQITASSPIDREEQSFHQLKVVARAG 847 Score = 350 bits (860), Expect = 4e-94 Identities = 269/890 (30%), Positives = 413/890 (46%), Gaps = 57/890 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D NDH P+F+ +Y + E G+ + + ATD D G+NA + Y+ LV+ + L Sbjct: 441 IFVNDINDHPPIFQETEYRVDISEDIPKGSYIKGVSATDGDSGQNANLRYS--LVSGNAL 498 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F I SG + + A LDRE + + + A DQ + R+ Sbjct: 499 G-----------------WFSISENSGLVTSAALLDREATSEVVLNISAKDQG--LQPRI 539 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S T I +NI D ND P F++ T+ VS+ E ++ + ATD D+G N +R++ Sbjct: 540 SYTKLI-INITDVNDQVPTFTQSTFHVSLAEHAPAGTQLLV--LSATDGDLGPNGTMRFS 596 Query: 191 IIGGN---TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 Q +F +D LSG +S LD E+ SY L ++ DGGSP + ++ + + Sbjct: 597 FDAETPAAAQGRFRLDPLSGRLSTAVELDREEQASYLLHVQVTDGGSPPLRSAGKVNVTL 656 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 RDVNDN P FY + +V EN P G + V A D D G N + Y +T D Sbjct: 657 RDVNDNRPVFYPLQYFANVKENEPSGSYVTTVSATDPDLGRNGTVKYMITAGDAA----- 711 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 I+ +G + T LDRE + YQL VTA DG A F Sbjct: 712 TFHINGNTGKISTLVPLDREEKTTYQLQVTAADGSGLRSHTPAIVTVSVLDTQDNPPVFS 771 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 Y + E+ GT V T++AT D + + Y IT G+ RG F++ N G IT + Sbjct: 772 QKGYSFVMFENVGVGTVVGTVSATTVDLNTNVSYLITSGDQRGLFAV---NSAGQITASS 828 Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 P+D +++ + L V A +G + V I + D N+ AP F +A S E+ G T Sbjct: 829 PIDREEQSFHQLKVVAR-AGQITGEVSVNITVKDLNDNAPRFIHAVEHVSAVENWSTGHT 887 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 + A+D D G N + YSL N H I+ + G IT L+ T S Y Sbjct: 888 IFQAKASDPDEGANGVVVYSLKQ---NPRGLFH-----IHEKHGLITLTGPLE-VTASSY 938 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 + V A D GVP + + + +SV DVNDN PVF Q Y I E V + +V ATD Sbjct: 939 EVEVIAEDMGVPKHTSSLVLIVSVYDVNDNSPVFDQLSYEVLIPESEPVNSRFFKVEATD 998 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 D G NG I Y++ + + F I P G + LDRE ++L VA D P Sbjct: 999 KDSGFNGEIVYDIAGGNTGD-VFGIFP-DGQLYIKAELDREIQERYNLVLVARDRAVEPL 1056 Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 S++V V + ++D+ND+ P+F S F+ E G+ +G + A D D GPN+ V Y+ + Sbjct: 1057 SASVNVSVILDDVNDNRPLFNSTNYVFHFEEEQQRGSLVGRVFAEDKDFGPNSEVRYTFE 1116 Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP----PLWNDVRVEIL 783 + + T + S A+ L + + V+ ++ PL + +V++ Sbjct: 1117 MPQPNFELNAITGELSSTAQF-DRESLMRQRGAAVFSFVVVSSDQGLPRPLKDQAKVQVY 1175 Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFP-VGPFGRVPAYDADVTDK--LQYRILSGNNANLI 840 + D+NDN P + + + P V RV A D D +QY + GN Sbjct: 1176 IQDINDNQPKFTK-DVYQASVSESAPNVTQLLRVSASDVDENKNGLVQYHVAEGNEEGQF 1234 Query: 841 LLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE-IKAMMQLSVRLITE 889 +++ ++G +TL +L+ ++++ DG E + + LS+ ++ E Sbjct: 1235 MIDSSSGQITLVGKLDYETTSSYSLKIIAVDGGAEPLSSSCMLSISVLDE 1284 Score = 344 bits (846), Expect = 2e-92 Identities = 281/902 (31%), Positives = 433/902 (48%), Gaps = 84/902 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND+ P FE Y+ASV E A+ G+++L + A+D D NAE+ Y ++ T Sbjct: 223 VTIQDINDNPPSFERDLYQASVLEDAAVGSSILQVTASDGDEAANAEIRYFLDEETP--- 279 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F+ID ++G ++ + LD E Y++ + A D P L Sbjct: 280 -------------------FQIDPKTGTIIIKEGLDYESRREYSLTIHAVDNGVP---SL 317 Query: 131 SSTATIHVNIIDDNDNYP-----QFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGAN 184 S A + ++D NDN P F + SVDE+ V V+A + +D+D AN Sbjct: 318 SGRAEATIKLLDVNDNDPVVKFRYFPTTSKFASVDENAQV--GTVVALLTVSDSDSSAAN 375 Query: 185 SAIRYAIIGGNTQMQFSI-DSLSGDVSLVK---TLDYEQVRSYRLVIRAQDGGSP-SRSN 239 I +I+GGN Q F + S ++SL+K LD E++ SY L + D G P +RS+ Sbjct: 376 GNISVSILGGNEQRHFEVHTSPVPNLSLIKVASVLDRERISSYNLTVSVSDNGKPVARSS 435 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 L+I + D+ND+ P F + ++ +SE++P G I V A D D G NA L Y++ Sbjct: 436 FASLVIFVNDINDHPPIFQETEYRVDISEDIPKGSYIKGVSATDGDSGQNANLRYSLV-- 493 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 +GN +I SG V ++ LDRE ++ L ++A D G PR + Sbjct: 494 --SGNALGWFSISENSGLVTSAALLDREATSEVVLNISAKDQGLQPRISYTKLIINITDV 551 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEI---TGGNTRGRFSI 414 F + V LAE P GT ++ L+ATD D + + + T +GRF + Sbjct: 552 NDQVPTFTQSTFHVSLAEHAPAGTQLLVLSATDGDLGPNGTMRFSFDAETPAAAQGRFRL 611 Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENA 472 +GR ++ A LD +++ Y+L V TD G + ++N+T D N+ PVF Sbjct: 612 DPLSGR--LSTAVELDREEQASYLLHVQVTDGGSPPLRSAGKVNVTLRDVNDNRPVFYPL 669 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 Y A+V E+ P G+ V VSATD D+G N + Y ++ + +A H IN TG Sbjct: 670 QYFANVKENEPSGSYVTTVSATDPDLGRNGTVKYMIT---AGDAATFH-----INGNTGK 721 Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592 I+T LDRE + Y L VTA DG V +SV+D DN PVF Q+ Y+ + E Sbjct: 722 ISTLVPLDREEKTTYQLQVTAADGSGLRSHTPAIVTVSVLDTQDNPPVFSQKGYSFVMFE 781 Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652 + VGT V V AT D LN + Y + D + G F ++ A G I + +DRE + Sbjct: 782 NVGVGTVVGTVSATTVD--LNTNVSYLITSGD-QRGLFAVNSA-GQITASSPIDREEQSF 837 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 H LK VA G + V V+I ++D+ND+ P F EN G TI + +A Sbjct: 838 HQLKVVARAGQI---TGEVSVNITVKDLNDNAPRFIHAVEHVSAVENWSTGHTIFQAKAS 894 Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRAAS 771 DPDEG N VV YS+K + F + + G L+T+ L+ + + E++ Sbjct: 895 DPDEGANGVVVYSLK-QNPRGLFHIHEKHG-----LITLTGPLEVTASSYEVEVIAEDMG 948 Query: 772 PPLWNDVRVEIL-VTDVNDNAPVMK--DFQIIFNNYKDCFPVGP-FGRVPAYDAD--VTD 825 P V I+ V DVNDN+PV ++++ + PV F +V A D D Sbjct: 949 VPKHTSSLVLIVSVYDVNDNSPVFDQLSYEVLI---PESEPVNSRFFKVEATDKDSGFNG 1005 Query: 826 KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSV 884 ++ Y I GN ++ + G + + +L+ + + + + D V + A + +SV Sbjct: 1006 EIVYDIAGGNTGDVFGI-FPDGQLYIKAELDREIQERYNLVLVARDRAVEPLSASVNVSV 1064 Query: 885 RL 886 L Sbjct: 1065 IL 1066 Score = 343 bits (844), Expect = 3e-92 Identities = 258/879 (29%), Positives = 426/879 (48%), Gaps = 74/879 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND+ PVF QY A+V+E SG+ V T+ ATD D+G+N V+Y ++TA Sbjct: 654 VTLRDVNDNRPVFYPLQYFANVKENEPSGSYVTTVSATDPDLGRNGTVKY---MITAG-- 708 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 DA F I+G +G + T LDRE+ Y + V A D + R Sbjct: 709 ---DAAT------------FHINGNTGKISTLVPLDREEKTTYQLQVTAADGSGL---RS 750 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + A + V+++D DN P FS+K Y+ + E++ V V+ + AT D+ N + Y Sbjct: 751 HTPAIVTVSVLDTQDNPPVFSQKGYSFVMFENVGV--GTVVGTVSATTVDLNTN--VSYL 806 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I G+ + F+++S +G ++ +D E+ ++L + A+ G + + I ++D+ Sbjct: 807 ITSGDQRGLFAVNS-AGQITASSPIDREEQSFHQLKVVARAG---QITGEVSVNITVKDL 862 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDNAPRF ++ S EN G++I + +A D DEG N + Y++ N Sbjct: 863 NDNAPRFIHAVEHVSAVENWSTGHTIFQAKASDPDEGANGVVVYSLKQ-----NPRGLFH 917 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I + G + +G L+ T + Y++ V A D G P +++ F Sbjct: 918 IHEKHGLITLTGPLE-VTASSYEVEVIAEDMGVPKHTSSLVLIVSVYDVNDNSPVFDQLS 976 Query: 371 YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 YEV + E EP + + ATD D + + Y+I GGNT F I G + + Sbjct: 977 YEVLIPESEPVNSRFFKVEATDKDSGFNGEIVYDIAGGNTGDVFGIFPD---GQLYIKAE 1033 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGT 486 LD + + RY L + A D +A V +++ D N+ P+F + Y E+ G+ Sbjct: 1034 LDREIQERYNLVLVARDRAVEPLSASVNVSVILDDVNDNRPLFNSTNYVFHFEEEQQRGS 1093 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM-- 544 V V A D D G N+++ Y+ N F +N TG +++ DRE++ Sbjct: 1094 LVGRVFAEDKDFGPNSEVRYTFEMPQPN---------FELNAITGELSSTAQFDRESLMR 1144 Query: 545 ----SGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 + + V + D G+P L D V++ + D+NDN+P F + +Y A++ E A T Sbjct: 1145 QRGAAVFSFVVVSSDQGLPRPLKDQAKVQVYIQDINDNQPKFTKDVYQASVSESAPNVTQ 1204 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 + +V A+D D NG + Y + + EEG F+ID +SG I LD E+ +++ LK +A Sbjct: 1205 LLRVSASDVDENKNGLVQYHV-AEGNEEGQFMIDSSSGQITLVGKLDYETTSSYSLKIIA 1263 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 +DGG P SS+ ++ I + D ND+ P F ++ + EN IG + + A D D GPN Sbjct: 1264 VDGGAEPLSSSCMLSISVLDENDNSPSFPKSSVSVDVLENMRIGELVASVTATDTDSGPN 1323 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776 A + YSI ++ +FS+ GS + + LDYE+ + Y+L + A P + Sbjct: 1324 ADITYSITATNNHGTFSISPNTGS----IFLVKKLDYET-QSVYKLNVSAKDNGRPSRSS 1378 Query: 777 DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAY--DADVTDKLQYRILS 833 + V I V D NDN P+ IF + + PV + A+ DAD+ +L+Y I+ Sbjct: 1379 SIPVIIHVRDFNDNPPIFTPGD-IFKSIPENLPVATSVMMIVAHDTDADINGQLEYSIVQ 1437 Query: 834 G-NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 N ++ +TG + + +++ L + V TD Sbjct: 1438 QVPRGNHFSIDASTGVLYTNQEVDREFSNLFELTVKATD 1476 Score = 312 bits (766), Expect = 9e-83 Identities = 208/624 (33%), Positives = 313/624 (50%), Gaps = 47/624 (7%) Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV------------GA 183 + + + D NDN P F V+++E++ D I ++ ATDAD G Sbjct: 1782 VEITLQDVNDNPPVFPNDILDVTIEENVG--DGFKIMQLTATDADELPYVSWLLFPSEGP 1839 Query: 184 NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 N+ + Y II G F ID SGD+ K LD E+ Y L++RA DG +S+ +L Sbjct: 1840 NALVTYTIISGADD-SFRIDPESGDLIATKKLDRERRSKYSLLVRADDG---KQSSDMRL 1895 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 I ++D+ND++P+F + + + E+ G + + A D+D GVN E+TY++ + D Sbjct: 1896 NITVKDINDHSPKFSRATYSFDIPEDTTAGSIVAAILASDSDSGVNGEVTYSLEEDDE-- 1953 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 D ++P +G + LD E Q Y L A DGG +++T Sbjct: 1954 --DETFLLNPVTGVFNVTRVLDYELQRYYILTARAQDGGG--QASTVRVYFNVLDVNDNP 2009 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRG 421 F Y ++E P G+ VVT+ A+DAD+ + +L Y I G+ +G F IT G Sbjct: 2010 PVFETTTYSASVSESLPAGSSVVTVVASDADDGPNAQLFYRIASGDPQGHFLITKD---G 2066 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGR-----SDTAMVQINITDANNYAPVFENAPYTA 476 + + LD + + Y L ++ D + TA V + + D N+ P F + T Sbjct: 2067 NLRTQKALDRETQSFYNLVITVNDLAPPPMTRFTSTAQVSVILLDVNDCPPTFTSQKMTY 2126 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 + E+ P+ T VL V A+DSD G N+ + YSL SN+ F I G + Sbjct: 2127 -IQENTPVDTVVLAVHASDSDSGPNSYVEYSLHGPFSNK--------FSIGTIDGDVRLV 2177 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 LDRE +S Y LTV A D G P LS T DV + V+DVNDN P F Q +Y I E+ L Sbjct: 2178 GELDREEISNYTLTVVATDKGEPPLSSTMDVTMVVLDVNDNTPSFSQNIYDIEIEENTLT 2237 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 GT V QV ATDAD G NG+I + + + + F I +G+I + LDRE+ +++ L Sbjct: 2238 GTDVIQVFATDADEGTNGQIRFSISGSNTD---FRIYSVTGMISVARQLDREARSSYSLL 2294 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN-SPIGTTIGEIRAHDPD 715 A D G+ P+ V+I + D+ND PVFE T + EN + T + ++ A D D Sbjct: 2295 VQATDRGSSPRMDQATVNIVLLDVNDCAPVFELSPYTVRVQENLENLPTNVLQVVARDDD 2354 Query: 716 EGPNAVVHYSIKGGDDSNSFSLET 739 +G N + Y + GG+D +FSL + Sbjct: 2355 QGANGQLSYMLSGGNDDGAFSLSS 2378 Score = 309 bits (759), Expect = 6e-82 Identities = 247/874 (28%), Positives = 388/874 (44%), Gaps = 62/874 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 IN+ D ND P F + S+ E A +GT +L L ATD D+G N + ++ + T Sbjct: 546 INITDVNDQVPTFTQSTFHVSLAEHAPAGTQLLVLSATDGDLGPNGTMRFSFDAETP--- 602 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 Q FR+D SG L T LDRE+ A Y + V+ TD SP L Sbjct: 603 -------------AAAQGRFRLDPLSGRLSTAVELDREEQASYLLHVQVTDGGSP---PL 646 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S ++V + D NDN P F Y +V E + + + ATD D+G N ++Y Sbjct: 647 RSAGKVNVTLRDVNDNRPVFYPLQYFANVKE--NEPSGSYVTTVSATDPDLGRNGTVKYM 704 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIRD 249 I G+ F I+ +G +S + LD E+ +Y+L + A D GS RS+T ++ +++ D Sbjct: 705 ITAGDA-ATFHINGNTGKISTLVPLDREEKTTYQLQVTAAD-GSGLRSHTPAIVTVSVLD 762 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 DN P F + + ENV +G + V A D +N ++Y +T D G + Sbjct: 763 TQDNPPVFSQKGYSFVMFENVGVGTVVGTVSATTVD--LNTNVSYLITSGDQRG-----L 815 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 +G + S +DRE Q+ +QL V A G + + F+ Sbjct: 816 FAVNSAGQITASSPIDREEQSFHQLKVVARAG---QITGEVSVNITVKDLNDNAPRFIHA 872 Query: 370 QYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 V E+ G + A+D DE N + N RG F I ++ GLIT+ P Sbjct: 873 VEHVSAVENWSTGHTIFQAKASDPDEGANGVVVYSLKQNPRGLFHIHEKH--GLITLTGP 930 Query: 429 LDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 L+ Y + V A D G T+ ++ +++ D N+ +PVF+ Y + E P+ + Sbjct: 931 LEVTAS-SYEVEVIAEDMGVPKHTSSLVLIVSVYDVNDNSPVFDQLSYEVLIPESEPVNS 989 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 V ATD D G N +I Y ++ + + F I P G + LDRE Sbjct: 990 RFFKVEATDKDSGFNGEIVYDIAGGNTGDV-------FGIFPD-GQLYIKAELDREIQER 1041 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y L + ARD V LS + +V + + DVNDN P+F Y + E+ G+ V +V A Sbjct: 1042 YNLVLVARDRAVEPLSASVNVSVILDDVNDNRPLFNSTNYVFHFEEEQQRGSLVGRVFAE 1101 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV------ATHDLKAVAI 660 D D G N + Y + + +F ++ +G + + DRES+ A V+ Sbjct: 1102 DKDFGPNSEVRYTF---EMPQPNFELNAITGELSSTAQFDRESLMRQRGAAVFSFVVVSS 1158 Query: 661 DGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 D G P P V + I+DIND+ P F D +SE++P T + + A D DE N Sbjct: 1159 DQGLPRPLKDQAKVQVYIQDINDNQPKFTKDVYQASVSESAPNVTQLLRVSASDVDENKN 1218 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR 779 +V Y + G++ F +++ G + LV +D + S + + + PL + Sbjct: 1219 GLVQYHVAEGNEEGQFMIDSSSG--QITLVGKLDYETTSSYSLKIIAVDGGAEPLSSSCM 1276 Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNA 837 + I V D NDN+P + + ++ V A D D + Y I + NN Sbjct: 1277 LSISVLDENDNSPSFPKSSVSVDVLENMRIGELVASVTATDTDSGPNADITYSITATNNH 1336 Query: 838 NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 ++ TGS+ L +L+ + + VS D Sbjct: 1337 GTFSISPNTGSIFLVKKLDYETQSVYKLNVSAKD 1370 Score = 307 bits (753), Expect = 3e-81 Identities = 221/662 (33%), Positives = 329/662 (49%), Gaps = 44/662 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I + D ND+ PVF + ++ E G ++ L ATD D E+ Y L+ Sbjct: 1783 EITLQDVNDNPPVFPNDILDVTIEENVGDGFKIMQLTATDAD-----ELPYVSWLLFPSE 1837 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 P D FRID SG L+ LDRE+ ++Y++LV+A D + Sbjct: 1838 -GPN--ALVTYTIISGADDSFRIDPESGDLIATKKLDRERRSKYSLLVRADD------GK 1888 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 SS +++ + D ND+ P+FS TY+ + ED T ++A I A+D+D G N + Y Sbjct: 1889 QSSDMRLNITVKDINDHSPKFSRATYSFDIPED--TTAGSIVAAILASDSDSGVNGEVTY 1946 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 ++ + F ++ ++G ++ + LDYE R Y L RAQDGG +++T ++ N+ D Sbjct: 1947 SLEEDDEDETFLLNPVTGVFNVTRVLDYELQRYYILTARAQDGG--GQASTVRVYFNVLD 2004 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 VNDN P F T+ + SVSE++P G S+V V A DAD+G NA+L Y + D G+ I Sbjct: 2005 VNDNPPVFETTTYSASVSESLPAGSSVVTVVASDADDGPNAQLFYRIASGDPQGH--FLI 2062 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR---SATATXXXXXXXXXXXXXXF 366 T D G + T LDRETQ+ Y L++T D PP ++TA F Sbjct: 2063 TKD---GNLRTQKALDRETQSFYNLVITVNDLAPPPMTRFTSTAQVSVILLDVNDCPPTF 2119 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT-GGNTRGRFSITSQNGRGLITV 425 Q + E+ P T V+ + A+D+D + E + G +FSI + +G + + Sbjct: 2120 -TSQKMTYIQENTPVDTVVLAVHASDSDSGPNSYVEYSLHGPFSNKFSIGTIDGD--VRL 2176 Query: 426 AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 LD ++ Y LTV ATD G S T V + + D N+ P F Y + E+ Sbjct: 2177 VGELDREEISNYTLTVVATDKGEPPLSSTMDVTMVVLDVNDNTPSFSQNIYDIEIEENTL 2236 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 GT V+ V ATD+D G N QI +S+S + F I TG I+ + LDRE Sbjct: 2237 TGTDVIQVFATDADEGTNGQIRFSISGS---------NTDFRIYSVTGMISVARQLDREA 2287 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED-ALVGTSVSQ 602 S Y L V A D G D V I ++DVND PVF+ YT + E+ + T+V Q Sbjct: 2288 RSSYSLLVQATDRGSSPRMDQATVNIVLLDVNDCAPVFELSPYTVRVQENLENLPTNVLQ 2347 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 V A D D G NG++ Y L ++G+F + + G +R + +DRE+ + L A D Sbjct: 2348 VVARDDDQGANGQLSYMLS-GGNDDGAFSLS-SGGQLRLTQTVDREARGEYILLITATDS 2405 Query: 663 GT 664 GT Sbjct: 2406 GT 2407 Score = 301 bits (739), Expect = 2e-79 Identities = 257/883 (29%), Positives = 406/883 (45%), Gaps = 69/883 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 ++VLD D+ PVF + Y + E GT V T+ AT D+ N V Y I + D Sbjct: 758 VSVLDTQDNPPVFSQKGYSFVMFENVGVGTVVGTVSATTVDL--NTNVSYLI--TSGDQ- 812 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + +F ++ +G + + +DRE+ + + + V A + ++ Sbjct: 813 ----------------RGLFAVNS-AGQITASSPIDREEQSFHQLKVVAR------AGQI 849 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + ++++ + D NDN P+F VS E+ S I + KA+D D GAN + Y+ Sbjct: 850 TGEVSVNITVKDLNDNAPRFIHAVEHVSAVENWST--GHTIFQAKASDPDEGANGVVVYS 907 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + N + F I G ++L L+ SY + + A+D G P +++ L++++ DV Sbjct: 908 L-KQNPRGLFHIHEKHGLITLTGPLEVT-ASSYEVEVIAEDMGVPKHTSSLVLIVSVYDV 965 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN+P F ++ + E+ P+ +V+A D D G N E+ Y + + TG+V Sbjct: 966 NDNSPVFDQLSYEVLIPESEPVNSRFFKVEATDKDSGFNGEIVYDIAGGN-TGDV---FG 1021 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I P G +Y +LDRE Q +Y L++ A D P SA+ F Sbjct: 1022 IFP-DGQLYIKAELDREIQERYNLVLVARDRAVEPLSASVNVSVILDDVNDNRPLFNSTN 1080 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 Y E++ G+ V + A D D T + F + + G T + Sbjct: 1081 YVFHFEEEQQRGSLVGRVFAEDKDFGPNSEVRYTFEMPQPNFELNAITGELSSTAQFDRE 1140 Query: 431 FKQERR----YVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 +R + V ++D G D A VQ+ I D N+ P F Y ASV E AP Sbjct: 1141 SLMRQRGAAVFSFVVVSSDQGLPRPLKDQAKVQVYIQDINDNQPKFTKDVYQASVSESAP 1200 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 T +L VSA+D D N + Y ++ NE + QF+I+ +G IT LD ET Sbjct: 1201 NVTQLLRVSASDVDENKNGLVQYHVAE--GNE-----EGQFMIDSSSGQITLVGKLDYET 1253 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 S Y L + A DGG LS + + ISV+D NDN P F + + +++E+ +G V+ V Sbjct: 1254 TSSYSLKIIAVDGGAEPLSSSCMLSISVLDENDNSPSFPKSSVSVDVLENMRIGELVASV 1313 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 ATD D G N I Y + + G+F I P +G I K LD E+ + + L A D G Sbjct: 1314 TATDTDSGPNADITYSITATNNH-GTFSISPNTGSIFLVKKLDYETQSVYKLNVSAKDNG 1372 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 P +SS++ V I + D ND+PP+F + I EN P+ T++ I AHD D N + Sbjct: 1373 RPSRSSSIPVIIHVRDFNDNPPIFTPGDIFKSIPENLPVATSVMMIVAHDTDADINGQLE 1432 Query: 724 YSI-KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR--- 779 YSI + N FS++ G L T ++D E +EL ++A + + R Sbjct: 1433 YSIVQQVPRGNHFSIDASTGV----LYTNQEVDREFSNL-FELTVKATDQAVPLETRRFA 1487 Query: 780 ---VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSG 834 V I VTD NDN P + + V AYD D +++Y ++ G Sbjct: 1488 LKNVTIWVTDQNDNIPTFLSQNALVAE-PNIMIGSILTTVVAYDPDEGANGEVEYELVEG 1546 Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIK 877 ++ I ++ +G + L+ QL + + ++ VS TD E K Sbjct: 1547 DSGTFI-MDRYSGDIRLASQLVPS-QLVYSLTVSATDHGTERK 1587 Score = 293 bits (719), Expect = 5e-77 Identities = 226/731 (30%), Positives = 348/731 (47%), Gaps = 62/731 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 ++V D ND+SPVF+ YE + E + ++ATD+D G N E+ Y I Sbjct: 960 VSVYDVNDNSPVFDQLSYEVLIPESEPVNSRFFKVEATDKDSGFNGEIVYDI-------- 1011 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 DVF I G L +A LDRE RY +++ A D+A + L Sbjct: 1012 -----------AGGNTGDVFGIFP-DGQLYIKAELDREIQERYNLVLVARDRAV---EPL 1056 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S++ + V + D NDN P F+ Y +E+ ++ ++ A D D G NS +RY Sbjct: 1057 SASVNVSVILDDVNDNRPLFNSTNYVFHFEEEQQ--RGSLVGRVFAEDKDFGPNSEVRYT 1114 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR------LVIRAQDGGSPSR-SNTTQL 243 Q F +++++G++S D E + R V+ + D G P + ++ Sbjct: 1115 F--EMPQPNFELNAITGELSSTAQFDRESLMRQRGAAVFSFVVVSSDQGLPRPLKDQAKV 1172 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 + I+D+NDN P+F ++Q SVSE+ P ++RV A D DE N + Y + + G Sbjct: 1173 QVYIQDINDNQPKFTKDVYQASVSESAPNVTQLLRVSASDVDENKNGLVQYHVAE----G 1228 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 N + ID SG + G+LD ET + Y L + A DGG P S++ Sbjct: 1229 NEEGQFMIDSSSGQITLVGKLDYETTSSYSLKIIAVDGGAEPLSSSCMLSISVLDENDNS 1288 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRG 421 F V++ E+ G V ++TATD D + Y IT N G FSI+ G Sbjct: 1289 PSFPKSSVSVDVLENMRIGELVASVTATDTDSGPNADITYSITATNNHGTFSISPNTGS- 1347 Query: 422 LITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVF 479 I + + LD++ + Y L VSA D+G RS + V I++ D N+ P+F S+ Sbjct: 1348 -IFLVKKLDYETQSVYKLNVSAKDNGRPSRSSSIPVIIHVRDFNDNPPIFTPGDIFKSIP 1406 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E+ P+ T+V+++ A D+D IN Q+ YS+ ++ +H F I+ TG + TN+ + Sbjct: 1407 ENLPVATSVMMIVAHDTDADINGQLEYSIVQQVPR---GNH---FSIDASTGVLYTNQEV 1460 Query: 540 DRETMSGYLLTVTARDGGVPSLSDT---TDVEISVVDVNDNEPVFKQQLYTANIME-DAL 595 DRE + + LTV A D VP + +V I V D NDN P F Q A + E + + Sbjct: 1461 DREFSNLFELTVKATDQAVPLETRRFALKNVTIWVTDQNDNIPTFLSQ--NALVAEPNIM 1518 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655 +G+ ++ V A D D G NG + YEL D G+F++D SG IR L S + L Sbjct: 1519 IGSILTTVVAYDPDEGANGEVEYELVEGD--SGTFIMDRYSGDIRLASQLV-PSQLVYSL 1575 Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 A D GT ++S + I ++ ++ PVF + E P GT + + A P Sbjct: 1576 TVSATDHGTERKTSRTDLTIILQGLDG--PVFSQPKYITILKEGQPPGTNVISLDASSP- 1632 Query: 716 EGPNAVVHYSI 726 G + V Y I Sbjct: 1633 RGSTSKVEYFI 1643 Score = 278 bits (681), Expect = 2e-72 Identities = 246/882 (27%), Positives = 407/882 (46%), Gaps = 84/882 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 Q+ + D ND+ P F Y+ASV E A + T +L + A+D D KN V+Y + Sbjct: 1173 QVYIQDINDNQPKFTKDVYQASVSESAPNVTQLLRVSASDVDENKNGLVQYHV------- 1225 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + F ID SG + LD E + Y++ + A D + + Sbjct: 1226 ------------AEGNEEGQFMIDSSSGQITLVGKLDYETTSSYSLKIIAVDGGA---EP 1270 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LSS+ + ++++D+NDN P F + + +V V E++ + + ++A + ATD D G N+ I Y Sbjct: 1271 LSSSCMLSISVLDENDNSPSFPKSSVSVDVLENMRIGE--LVASVTATDTDSGPNADITY 1328 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 +I N FSI +G + LVK LDYE Y+L + A+D G PSRS++ ++I++RD Sbjct: 1329 SITATNNHGTFSISPNTGSIFLVKKLDYETQSVYKLNVSAKDNGRPSRSSSIPVIIHVRD 1388 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 NDN P F +S+ EN+P+ S++ + A+D D +N +L Y++ + GN Sbjct: 1389 FNDNPPIFTPGDIFKSIPENLPVATSVMMIVAHDTDADINGQLEYSIVQQVPRGN---HF 1445 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP---PRSATATXXXXXXXXXXXXXXF 366 +ID +G +YT+ ++DRE ++L V ATD P R A F Sbjct: 1446 SIDASTGVLYTNQEVDREFSNLFELTVKATDQAVPLETRRFALKNVTIWVTDQNDNIPTF 1505 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLIT 424 + Q + + G+ + T+ A D DE + + YE+ G++ G F + +G I Sbjct: 1506 L-SQNALVAEPNIMIGSILTTVVAYDPDEGANGEVEYELVEGDS-GTFIMDRYSGD--IR 1561 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 +A L + Y LTVSATD G T+ + I PVF Y + E P Sbjct: 1562 LASQL-VPSQLVYSLTVSATDHGTERKTSRTDLTIILQGLDGPVFSQPKYITILKEGQPP 1620 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 GT V+ + A+ S G +++ Y + + S A + F I +G I T LD Sbjct: 1621 GTNVISLDAS-SPRGSTSKVEYFIVAVHSGGKAA--GRLFTIGRHSGVIQTAAELD---- 1673 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 R+ G SD V++ ++ + ++P Q+ T N+ ++ G Sbjct: 1674 ---------REQG----SDLYLVDVYAIESDASQPR-TQRAETQNLGGFLDRLDQENRAG 1719 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 + A L + P + + V+ + G T+ E + ++ +++ T Sbjct: 1720 SPSAAGWLPSTVRLWKQPVPQPQLEGVLPGSLG--GTDNVDPFEFLG--QIQRLSLGVCT 1775 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD----------- 713 P ++ + V I ++D+ND+PPVF +D L I EN G I ++ A D Sbjct: 1776 P--NNLMEVEITLQDVNDNPPVFPNDILDVTIEENVGDGFKIMQLTATDADELPYVSWLL 1833 Query: 714 -PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP 772 P EGPNA+V Y+I G D +SF ++ G +L+ LD E R KY L++RA Sbjct: 1834 FPSEGPNALVTYTIISGAD-DSFRIDPESG----DLIATKKLDRER-RSKYSLLVRADDG 1887 Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYR 830 +D+R+ I V D+ND++P F+ +D + A D+D V ++ Y Sbjct: 1888 KQSSDMRLNITVKDINDHSPKFSRATYSFDIPEDTTAGSIVAAILASDSDSGVNGEVTYS 1947 Query: 831 ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 + + LLN TG ++ L+ + + + DG Sbjct: 1948 LEEDDEDETFLLNPVTGVFNVTRVLDYELQRYYILTARAQDG 1989 Score = 273 bits (669), Expect = 5e-71 Identities = 208/658 (31%), Positives = 316/658 (48%), Gaps = 54/658 (8%) Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD------------ 285 +N ++ I ++DVNDN P F + ++ ENV G+ I+++ A DAD Sbjct: 1777 NNLMEVEITLQDVNDNPPVFPNDILDVTIEENVGDGFKIMQLTATDADELPYVSWLLFPS 1836 Query: 286 EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP 345 EG NA +TYT+ D IDP SG + + +LDRE ++KY LLV A DG Sbjct: 1837 EGPNALVTYTI-----ISGADDSFRIDPESGDLIATKKLDRERRSKYSLLVRADDG---K 1888 Query: 346 RSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI 403 +S+ F Y ++ ED G+ V + A+D+D + + Y + Sbjct: 1889 QSSDMRLNITVKDINDHSPKFSRATYSFDIPEDTTAGSIVAAILASDSDSGVNGEVTYSL 1948 Query: 404 TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDAN 463 + F + G+ V + LD++ +R Y+LT A D GG++ T V N+ D N Sbjct: 1949 EEDDEDETFLLNPVT--GVFNVTRVLDYELQRYYILTARAQDGGGQASTVRVYFNVLDVN 2006 Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523 + PVFE Y+ASV E P G++V+ V A+D+D G NAQ+ Y ++ S + H Sbjct: 2007 DNPPVFETTTYSASVSESLPAGSSVVTVVASDADDGPNAQLFYRIA---SGDPQGH---- 2059 Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL---SDTTDVEISVVDVNDNEPV 580 F+I + G + T K LDRET S Y L +T D P + + T V + ++DVND P Sbjct: 2060 FLIT-KDGNLRTQKALDRETQSFYNLVITVNDLAPPPMTRFTSTAQVSVILLDVNDCPPT 2118 Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640 F Q T I E+ V T V V A+D+D G N + Y L F I G +R Sbjct: 2119 FTSQKMT-YIQENTPVDTVVLAVHASDSDSGPNSYVEYSL--HGPFSNKFSIGTIDGDVR 2175 Query: 641 TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700 LDRE ++ + L VA D G PP SST+ V + + D+ND+ P F + I EN+ Sbjct: 2176 LVGELDREEISNYTLTVVATDKGEPPLSSTMDVTMVVLDVNDNTPSFSQNIYDIEIEENT 2235 Query: 701 PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760 GT + ++ A D DEG N + +SI G SN+ + R S + LD E+ R Sbjct: 2236 LTGTDVIQVFATDADEGTNGQIRFSISG---SNT---DFRIYSVTGMISVARQLDREA-R 2288 Query: 761 KKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPV--MKDFQIIFNNYKDCFPVGPFGR 815 Y L+++A S P + V I++ DVND APV + + + + P + Sbjct: 2289 SSYSLLVQATDRGSSPRMDQATVNIVLLDVNDCAPVFELSPYTVRVQENLENLPTNVL-Q 2347 Query: 816 VPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 V A D D +L Y + GN+ L+ + G + L+ ++ + ++ TD Sbjct: 2348 VVARDDDQGANGQLSYMLSGGNDDGAFSLS-SGGQLRLTQTVDREARGEYILLITATD 2404 Score = 250 bits (613), Expect = 3e-64 Identities = 246/919 (26%), Positives = 410/919 (44%), Gaps = 77/919 (8%) Query: 2 SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 S+P IH V D ND+ P+F S+ E T+V+ + A D D N ++EY+ Sbjct: 1379 SIPVIIH----VRDFNDNPPIFTPGDIFKSIPENLPVATSVMMIVAHDTDADINGQLEYS 1434 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121 I P + F ID +G L T +DRE + + VKATD Sbjct: 1435 IVQQV-----PRG-------------NHFSIDASTGVLYTNQEVDREFSNLFELTVKATD 1476 Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181 QA P+ R + + + + D NDN P F + V+ + ++ ++ + A D D Sbjct: 1477 QAVPLETRRFALKNVTIWVTDQNDNIPTFLSQNALVA---EPNIMIGSILTTVVAYDPDE 1533 Query: 182 GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 GAN + Y ++ G++ F +D SGD+ L L Q+ Y L + A D G+ +++ T Sbjct: 1534 GANGEVEYELVEGDSG-TFIMDRYSGDIRLASQLVPSQL-VYSLTVSATDHGTERKTSRT 1591 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 L I ++ + + P F + + E P G +++ + A + G +++ Y + Sbjct: 1592 DLTIILQGL--DGPVFSQPKYITILKEGQPPGTNVISLDA-SSPRGSTSKVEYFIVAVHS 1648 Query: 302 TGN-VDLPITIDPRSGWVYTSGQLDRETQAKYQLL-VTATDG-GDPPRSATATXXXXXXX 358 G TI SG + T+ +LDRE + L+ V A + PR+ A Sbjct: 1649 GGKAAGRLFTIGRHSGVIQTAAELDREQGSDLYLVDVYAIESDASQPRTQRAETQNLGGF 1708 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQN 418 G A P + + L + G + F Q Sbjct: 1709 LDRLDQENRAG--SPSAAGWLPSTVRLWKQPVPQPQLEGVLPGSLGGTDNVDPFEFLGQI 1766 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASV 478 R + V P + + + V+ +D +++T N F+ TA+ Sbjct: 1767 QRLSLGVCTPNNLMEVEITLQDVNDNPPVFPNDI----LDVTIEENVGDGFKIMQLTATD 1822 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 ++ P + +L S G NA +TY++ ++ D F I+P++G + K Sbjct: 1823 ADELPYVSWLLFPSE-----GPNALVTYTI--------ISGADDSFRIDPESGDLIATKK 1869 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 LDRE S Y L V A DG S + I+V D+ND+ P F + Y+ +I ED G+ Sbjct: 1870 LDRERRSKYSLLVRADDG---KQSSDMRLNITVKDINDHSPKFSRATYSFDIPEDTTAGS 1926 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 V+ + A+D+D G+NG + Y L+ D +E +F+++P +GV + LD E + L A Sbjct: 1927 IVAAILASDSDSGVNGEVTYSLEEDDEDE-TFLLNPVTGVFNVTRVLDYELQRYYILTAR 1985 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 A DGG Q+STV V+ + D+ND+PPVFE+ + +SE+ P G+++ + A D D+GP Sbjct: 1986 AQDGG--GQASTVRVYFNVLDVNDNPPVFETTTYSASVSESLPAGSSVVTVVASDADDGP 2043 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPL- 774 NA + Y I GD F L T+ G+ L T LD E+ + Y LVI A PP+ Sbjct: 2044 NAQLFYRIASGDPQGHF-LITKDGN----LRTQKALDRET-QSFYNLVITVNDLAPPPMT 2097 Query: 775 --WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDAD--VTDKLQY 829 + +V +++ DVND P ++ + ++ PV V A D+D ++Y Sbjct: 2098 RFTSTAQVSVILLDVNDCPPTFTSQKMTY--IQENTPVDTVVLAVHASDSDSGPNSYVEY 2155 Query: 830 RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLIT 888 L G +N + G + L +L+ T+ V TD G + + M +++ ++ Sbjct: 2156 S-LHGPFSNKFSIGTIDGDVRLVGELDREEISNYTLTVVATDKGEPPLSSTMDVTMVVLD 2214 Query: 889 EEMLLNSITVRLNDMTAEQ 907 S + + D+ E+ Sbjct: 2215 VNDNTPSFSQNIYDIEIEE 2233 Score = 247 bits (604), Expect = 4e-63 Identities = 211/674 (31%), Positives = 314/674 (46%), Gaps = 69/674 (10%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 D ND+ P+F Y E G+ V + A D+D G N+EV YT E+ Sbjct: 1068 DVNDNRPLFNSTNYVFHFEEEQQRGSLVGRVFAEDKDFGPNSEVRYTFEMP--------- 1118 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR------YTVLVKATDQASPVSD 128 Q F ++ +G L + A DRE + R ++ +V ++DQ P Sbjct: 1119 ------------QPNFELNAITGELSSTAQFDRESLMRQRGAAVFSFVVVSSDQGLPRP- 1165 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 L A + V I D NDN P+F++ Y SV E S + + ++ A+D D N ++ Sbjct: 1166 -LKDQAKVQVYIQDINDNQPKFTKDVYQASVSE--SAPNVTQLLRVSASDVDENKNGLVQ 1222 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y + GN + QF IDS SG ++LV LDYE SY L I A DGG+ S++ L I++ Sbjct: 1223 YHVAEGNEEGQFMIDSSSGQITLVGKLDYETTSSYSLKIIAVDGGAEPLSSSCMLSISVL 1282 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D NDN+P F S V EN+ IG + V A D D G NA++TY++T + G Sbjct: 1283 DENDNSPSFPKSSVSVDVLENMRIGELVASVTATDTDSGPNADITYSITATNNHGT---- 1338 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 +I P +G ++ +LD ETQ+ Y+L V+A D G P RS++ F P Sbjct: 1339 FSISPNTGSIFLVKKLDYETQSVYKLNVSAKDNGRPSRSSSIPVIIHVRDFNDNPPIFTP 1398 Query: 369 GQYEVELAEDEPPGTPVVTLTA--TDADEDNRLHYEITGGNTRG-RFSITSQNGRGLITV 425 G + E+ P T V+ + A TDAD + +L Y I RG FSI + G++ Sbjct: 1399 GDIFKSIPENLPVATSVMMIVAHDTDADINGQLEYSIVQQVPRGNHFSIDAST--GVLYT 1456 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAM-----VQINITDANNYAPVFENAPYTASVFE 480 Q +D + + LTV ATD +T V I +TD N+ P F A V E Sbjct: 1457 NQEVDREFSNLFELTVKATDQAVPLETRRFALKNVTIWVTDQNDNIPTF--LSQNALVAE 1514 Query: 481 -DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKL 538 + IG+ + V A D D G N ++ Y E V F+++ +G I ++L Sbjct: 1515 PNIMIGSILTTVVAYDPDEGANGEVEY--------ELVEGDSGTFIMDRYSGDIRLASQL 1566 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 + + + Y LTV+A D G + TD+ I + ++ PVF Q Y + E GT Sbjct: 1567 VPSQLV--YSLTVSATDHGTERKTSRTDLTIILQGLDG--PVFSQPKYITILKEGQPPGT 1622 Query: 599 SVSQVGATDADVGLNGRIHY---ELDPKDREEGS-FVIDPASGVIRTNKALDRE---SVA 651 +V + A+ + G ++ Y + + G F I SGVI+T LDRE + Sbjct: 1623 NVISLDAS-SPRGSTSKVEYFIVAVHSGGKAAGRLFTIGRHSGVIQTAAELDREQGSDLY 1681 Query: 652 THDLKAVAIDGGTP 665 D+ A+ D P Sbjct: 1682 LVDVYAIESDASQP 1695 Score = 246 bits (603), Expect = 5e-63 Identities = 185/560 (33%), Positives = 267/560 (47%), Gaps = 55/560 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D NDHSP F Y + E ++G+ V + A+D D G N EV Y++E Sbjct: 1897 ITVKDINDHSPKFSRATYSFDIPEDTTAGSIVAAILASDSDSGVNGEVTYSLEE------ 1950 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + ED + F ++ +G LD E Y + +A D Sbjct: 1951 DDED-------------ETFLLNPVTGVFNVTRVLDYELQRYYILTARAQDGGGQ----- 1992 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +ST ++ N++D NDN P F TY+ SV E + + + + A+DAD G N+ + Y Sbjct: 1993 ASTVRVYFNVLDVNDNPPVFETTTYSASVSESLPAGSS--VVTVVASDADDGPNAQLFYR 2050 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS---NTTQLLINI 247 I G+ Q F I G++ K LD E Y LVI D P + +T Q+ + + Sbjct: 2051 IASGDPQGHFLITK-DGNLRTQKALDRETQSFYNLVITVNDLAPPPMTRFTSTAQVSVIL 2109 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 DVND P F TS + EN P+ ++ V A D+D G N+ + Y++ G Sbjct: 2110 LDVNDCPPTF-TSQKMTYIQENTPVDTVVLAVHASDSDSGPNSYVEYSLH-----GPFSN 2163 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 +I G V G+LDRE + Y L V ATD G+PP S+T F Sbjct: 2164 KFSIGTIDGDVRLVGELDREEISNYTLTVVATDKGEPPLSSTMDVTMVVLDVNDNTPSFS 2223 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGR-FSITSQNGRGLIT 424 Y++E+ E+ GT V+ + ATDADE + ++ + I+G NT R +S+T G+I+ Sbjct: 2224 QNIYDIEIEENTLTGTDVIQVFATDADEGTNGQIRFSISGSNTDFRIYSVT-----GMIS 2278 Query: 425 VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 VA+ LD + Y L V ATD G R D A V I + D N+ APVFE +PYT V E+ Sbjct: 2279 VARQLDREARSSYSLLVQATDRGSSPRMDQATVNIVLLDVNDCAPVFELSPYTVRVQENL 2338 Query: 483 P-IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 + T VL V A D D G N Q++Y LS + D F ++ G + + +DR Sbjct: 2339 ENLPTNVLQVVARDDDQGANGQLSYMLSG-------GNDDGAFSLS-SGGQLRLTQTVDR 2390 Query: 542 ETMSGYLLTVTARDGGVPSL 561 E Y+L +TA D G L Sbjct: 2391 EARGEYILLITATDSGTSVL 2410 Score = 183 bits (446), Expect = 5e-44 Identities = 145/517 (28%), Positives = 237/517 (45%), Gaps = 34/517 (6%) Query: 372 EVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431 E ++ E++P GT V T+ + + + + FSI +G +I+ + +D Sbjct: 33 EFQVLEEQPVGTYVGTI-------ETKPSFTYRFSESHRLFSINGSSG--VISTSAVIDR 83 Query: 432 KQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491 + + V+ V S T V+I + D N+ +PVF +A S EDA G V++ Sbjct: 84 EALQSDVINVVVLSSQPTYPTE-VRIVVLDINDNSPVFPDASIVVSFKEDASSGRQVILD 142 Query: 492 SATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ-TGA---ITTNKLLDRETMSGY 547 +ATD+D+G N + ++ + +NP GA + + LDRE Y Sbjct: 143 TATDTDIGSNG-VDHTTYRIVKGNEQRKFRLDITVNPSGEGAFLHLVSTGGLDREVTPFY 201 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 L + D G P V +++ D+NDN P F++ LY A+++EDA VG+S+ QV A+D Sbjct: 202 QLLIEVEDKGEPKTFGYLQVNVTIQDINDNPPSFERDLYQASVLEDAAVGSSILQVTASD 261 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 D N I Y LD EE F IDP +G I + LD ES + L A+D G P Sbjct: 262 GDEAANAEIRYFLD----EETPFQIDPKTGTIIIKEGLDYESRREYSLTIHAVDNGVPSL 317 Query: 668 SSTVIVHIKIEDINDSPPV-----FESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAV 721 S IK+ D+ND+ PV F + + EN+ +GT + + D D N Sbjct: 318 SGRAEATIKLLDVNDNDPVVKFRYFPTTSKFASVDENAQVGTVVALLTVSDSDSSAANGN 377 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA--SPPLWND-- 777 + SI GG++ F + T + + + LD E Y L + + P+ Sbjct: 378 ISVSILGGNEQRHFEVHTSPVPNLSLIKVASVLDRER-ISSYNLTVSVSDNGKPVARSSF 436 Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR-VPAYDAD--VTDKLQYRILSG 834 + I V D+ND+ P+ ++ + + +D P G + + V A D D L+Y ++SG Sbjct: 437 ASLVIFVNDINDHPPIFQETEYRVDISED-IPKGSYIKGVSATDGDSGQNANLRYSLVSG 495 Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 N ++E +G +T + L+ + +S D Sbjct: 496 NALGWFSISENSGLVTSAALLDREATSEVVLNISAKD 532 >UniRef50_A7SLK9 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1677 Score = 373 bits (917), Expect = e-101 Identities = 284/883 (32%), Positives = 419/883 (47%), Gaps = 57/883 (6%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 I Q+ V D ND+ P F Y +RE TT ATD D G N V+YTI + Sbjct: 79 ISVQVQVDDINDNEPRFPTLYYTLRIRESMDVNTTNPINTATDPDAGNNGTVDYTI--AS 136 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 D + G + ++T+ LDRE Y + + ATD+ +P Sbjct: 137 GDN-----------TATFSLGTTACPTGSTLCVITKKPLDRETTDFYQLNITATDRGTPA 185 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 L I++ I+D+ND+ P F++ +Y S+ E + I ++ A D D G+N Sbjct: 186 ---LMGYCLINITILDENDHAPVFTQNSYLGSIAE--NTKPGVSILRVSAADRDSGSNGD 240 Query: 187 IRYAIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 I+YAI Q F +DS +G + + LD+E SY + A DGG PS+++ + Sbjct: 241 IKYAIDWDAIQSNSIFDLDSSTGVIRTKQNLDFEVKNSYTFNVIASDGGVPSKNDLATVT 300 Query: 245 INIRDVNDNAPRFYTSLF-----QESV-SENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 IN+ D NDN+P+ + +++ SEN I +I + D D N++ +T+ Sbjct: 301 INVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINTNIAYILVTDKDSNTNSQTELKITN 360 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358 D G + ++ LDRE Y L + TD G P RS Sbjct: 361 GDDEGCFKVEFL---GFYFIQLQKPLDRELVPFYNLTLNVTDKGVPSRSTLGFVLIDVTD 417 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRGRFSITS 416 F Y ++E G+ V+ L ATD DE DN + Y ITGGN G F + Sbjct: 418 VNDNSPAFTSNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSITGGNDLGWFQVDF 477 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPY 474 Q+ GL+T A+PLD +Q +T++A D G ++ + V + I D N+ P F + Y Sbjct: 478 QS--GLVTTAKPLDREQVSSVTITITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSY 535 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 ++ E A IG TVL VSATD D G N +ITY +SS + A + F +N QTG + Sbjct: 536 KGTISEGASIGATVLQVSATDVDSGDNGRITYEISS-----SDAQVNGLFELNTQTGVLW 590 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 T LDRET S Y TV A+D G P L + VE+++ D+NDN PVF Y A+IME+ Sbjct: 591 TKSQLDRETKSLYSFTVLAKDHGDPQLMSSVKVELTISDINDNAPVFYPVEYFASIMENE 650 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654 G + QV ATDAD G N I Y++ G+F ID ++GVI T +LD E Sbjct: 651 PPG-KLLQVTATDADEGTNAVISYDI-IGGNNNGNFSIDSSTGVISTLASLDHEVEEFFS 708 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 L A DGG + T +V++ + + D+ PVF + F + EN P GT +G + A Sbjct: 709 LIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVYENVPKGTLVGRVYATTK 768 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---AS 771 D+ N + Y+I GD +N F +++ G K D+D E + +Y L + A Sbjct: 769 DK--NGSISYAIVSGDPTNLFLVDSTGGIIKIN----GDMDREE-KAQYLLAVIARVGTV 821 Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF---GRVPAYDADVTDKLQ 828 PL V I V D NDNAP +I + + VG DA ++ Sbjct: 822 KPLSAQATVNIEVLDRNDNAPQFSTSSVIV-DIDGTWLVGQVVYNAAAVDLDAGKNGLVR 880 Query: 829 YRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 Y+ L+ N L+ +N T+G + L+ +L T++V +D Sbjct: 881 YQ-LTSNAEGLLWINSTSGVIKLARKLTDGDETQYTVQVLASD 922 Score = 348 bits (855), Expect = 2e-93 Identities = 254/791 (32%), Positives = 397/791 (50%), Gaps = 53/791 (6%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQAS-PVSDRLSSTATIHVNIIDDNDNYP 148 F + +G + T A +DRE + ++ ++ + ++ P+S + V + D NDN P Sbjct: 42 FGFNSNTGVISTTARIDRETTTQISLQLRTLNPSNQPIS--------VQVQVDDINDNEP 93 Query: 149 QFSEKTYTVSVDEDISV-TDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS- 206 +F YT+ + E + V T NP+ ATD D G N + Y I G+ FS+ + + Sbjct: 94 RFPTLYYTLRIRESMDVNTTNPINT---ATDPDAGNNGTVDYTIASGDNTATFSLGTTAC 150 Query: 207 --GDVSLV---KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261 G V K LD E Y+L I A D G+P+ + I I D ND+AP F + Sbjct: 151 PTGSTLCVITKKPLDRETTDFYQLNITATDRGTPALMGYCLINITILDENDHAPVFTQNS 210 Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321 + S++EN G SI+RV A D D G N ++ Y + D D + + +D +G + T Sbjct: 211 YLGSIAENTKPGVSILRVSAADRDSGSNGDIKYAI-DWDAIQSNSI-FDLDSSTGVIRTK 268 Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX----XXFMP---GQYEVE 374 LD E + Y V A+DGG P ++ AT ++P G + Sbjct: 269 QNLDFEVKNSYTFNVIASDGGVPSKNDLATVTINVLDTNDNSPQLKITYLPPHNGDKAIR 328 Query: 375 LAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432 +E+ T + + TD D +++ +IT G+ G F + G I + +PLD + Sbjct: 329 -SENSLINTNIAYILVTDKDSNTNSQTELKITNGDDEGCFKVEFL-GFYFIQLQKPLDRE 386 Query: 433 QERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 Y LT++ TD G RS V I++TD N+ +P F + YTA++ E A G+ VL Sbjct: 387 LVPFYNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQ 446 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550 ++ATD D G N ++YS++ N+ F ++ Q+G +TT K LDRE +S +T Sbjct: 447 LNATDPDEGDNGTVSYSITG--GNDL-----GWFQVDFQSGLVTTAKPLDREQVSSVTIT 499 Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610 +TA+D G + +T V ++++D NDN+P F + Y I E A +G +V QV ATD D Sbjct: 500 ITAQDHGSAPKTGSTTVTVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDS 559 Query: 611 GLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669 G NGRI YE+ D + G F ++ +GV+ T LDRE+ + + +A D G P S Sbjct: 560 GDNGRITYEISSSDAQVNGLFELNTQTGVLWTKSQLDRETKSLYSFTVLAKDHGDPQLMS 619 Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729 +V V + I DIND+ PVF I EN P G + ++ A D DEG NAV+ Y I GG Sbjct: 620 SVKVELTISDINDNAPVFYPVEYFASIMENEPPGKLL-QVTATDADEGTNAVISYDIIGG 678 Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTD 786 +++ +FS+++ G + T+ LD+E + + L+I A + V + V + Sbjct: 679 NNNGNFSIDSSTG----VISTLASLDHE-VEEFFSLIISAKDGGNKYAAKTAVVNVTVLN 733 Query: 787 VNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDKLQYRILSGNNANLILLNET 845 DN PV F Y++ P G GRV A D + Y I+SG+ NL L++ T Sbjct: 734 KADNLPVFLYEMYNFTVYEN-VPKGTLVGRVYATTKDKNGSISYAIVSGDPTNLFLVDST 792 Query: 846 TGSMTLSPQLN 856 G + ++ ++ Sbjct: 793 GGIIKINGDMD 803 Score = 348 bits (855), Expect = 2e-93 Identities = 258/842 (30%), Positives = 400/842 (47%), Gaps = 64/842 (7%) Query: 11 INVLDCNDHSPVFEMQQY-----EASVR-EGASSGTTVLTLKATDQDIGKNAEVEYTIEL 64 INVLD ND+SP ++ + ++R E + T + + TD+D N++ E I Sbjct: 301 INVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINTNIAYILVTDKDSNTNSQTELKIT- 359 Query: 65 VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLT-RASLDREKVARYTVLVKATDQA 123 N +D + F+++ + + LDRE V Y + + TD+ Sbjct: 360 ------NGDD------------EGCFKVEFLGFYFIQLQKPLDRELVPFYNLTLNVTDKG 401 Query: 124 SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183 P S+ + +++ D NDN P F+ YT ++ E + + ++ ATD D G Sbjct: 402 VPSR---STLGFVLIDVTDVNDNSPAFTSNAYTANISE--LAQNGSYVLQLNATDPDEGD 456 Query: 184 NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 N + Y+I GGN F +D SG V+ K LD EQV S + I AQD GS ++ +T + Sbjct: 457 NGTVSYSITGGNDLGWFQVDFQSGLVTTAKPLDREQVSSVTITITAQDHGSAPKTGSTTV 516 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 + I D NDN PRF S ++ ++SE IG ++++V A D D G N +TY ++ D Sbjct: 517 TVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEISSSD--A 574 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 V+ ++ ++G ++T QLDRET++ Y V A D GDP ++ Sbjct: 575 QVNGLFELNTQTGVLWTKSQLDRETKSLYSFTVLAKDHGDPQLMSSVKVELTISDINDNA 634 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRG 421 F P +Y + E+EPPG ++ +TATDADE + Y+I GGN G FSI S G Sbjct: 635 PVFYPVEYFASIMENEPPG-KLLQVTATDADEGTNAVISYDIIGGNNNGNFSIDSST--G 691 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVF 479 +I+ LD + E + L +SA D G + + TA+V + + + + PVF Y +V+ Sbjct: 692 VISTLASLDHEVEEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLYEMYNFTVY 751 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E+ P GT V V AT D N I+Y++ +S + F+++ G I N + Sbjct: 752 ENVPKGTLVGRVYATTKDK--NGSISYAI---VSGDPT----NLFLVDSTGGIIKINGDM 802 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 DRE + YLL V AR G V LS V I V+D NDN P F +I LVG Sbjct: 803 DREEKAQYLLAVIARVGTVKPLSAQATVNIEVLDRNDNAPQFSTSSVIVDIDGTWLVGQV 862 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 V A D D G NG + Y+L EG I+ SGVI+ + L + ++ +A Sbjct: 863 VYNAAAVDLDAGKNGLVRYQL--TSNAEGLLWINSTSGVIKLARKLTDGDETQYTVQVLA 920 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 D G+PPQ ST+ +HI + IN PP F ++ + P+ + A D D G N Sbjct: 921 SDSGSPPQHSTMTIHITL-SIN-HPPKFTLSSYVTHVLASQPLSYQFFYVVAVDQDSGKN 978 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWN 776 + YSI G++ F + +L L ++ + Y+L++RA P Sbjct: 979 GQLFYSIPQGNEEGLFGI-----FPGGKLYIRKSL-LQALKGSYDLIVRATDGGVPSFSA 1032 Query: 777 DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY--DADVTDKLQYRILSG 834 V V I + D ND+ + + F ++ P G + A+ D T + Y ++S Sbjct: 1033 SVPVTIYIQDSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYSLISS 1092 Query: 835 NN 836 + Sbjct: 1093 ES 1094 Score = 346 bits (851), Expect = 5e-93 Identities = 262/878 (29%), Positives = 407/878 (46%), Gaps = 63/878 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+V D ND+SP F Y A++ E A +G+ VL L ATD D G N V Y+I Sbjct: 413 IDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSIT------- 465 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 D F++D +SG + T LDRE+V+ T+ + A D S + + Sbjct: 466 GGNDLGW------------FQVDFQSGLVTTAKPLDREQVSSVTITITAQDHGS--APKT 511 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 ST T+ V IID NDN P+F + +Y ++ E S+ + ++ ATD D G N I Y Sbjct: 512 GST-TVTVTIIDGNDNKPRFMKSSYKGTISEGASI--GATVLQVSATDVDSGDNGRITYE 568 Query: 191 IIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 I + Q+ F +++ +G + LD E Y + A+D G P ++ ++ + I Sbjct: 569 ISSSDAQVNGLFELNTQTGVLWTKSQLDRETKSLYSFTVLAKDHGDPQLMSSVKVELTIS 628 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D+NDNAP FY + S+ EN P G +++V A DADEG NA ++Y + + GN Sbjct: 629 DINDNAPVFYPVEYFASIMENEPPG-KLLQVTATDADEGTNAVISYDIIGGNNNGN---- 683 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 +ID +G + T LD E + + L+++A DGG+ + TA F+ Sbjct: 684 FSIDSSTGVISTLASLDHEVEEFFSLIISAKDGGNKYAAKTAVVNVTVLNKADNLPVFLY 743 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 Y + E+ P GT V + AT D++ + Y I G+ F + S G +I + Sbjct: 744 EMYNFTVYENVPKGTLVGRVYATTKDKNGSISYAIVSGDPTNLFLVDSTGG--IIKINGD 801 Query: 429 LDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 +D +++ +Y+L V A + S A V I + D N+ AP F + + +G Sbjct: 802 MDREEKAQYLLAVIARVGTVKPLSAQATVNIEVLDRNDNAPQFSTSSVIVDIDGTWLVGQ 861 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 V +A D D G N + Y L+S IN +G I + L + Sbjct: 862 VVYNAAAVDLDAGKNGLVRYQLTSNAEG--------LLWINSTSGVIKLARKLTDGDETQ 913 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y + V A D G P T + I++ +N + P F Y +++ + V A Sbjct: 914 YTVQVLASDSGSPPQHSTMTIHITL-SIN-HPPKFTLSSYVTHVLASQPLSYQFFYVVAV 971 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D D G NG++ Y + P+ EEG F I P G + K+L + ++DL A DGG P Sbjct: 972 DQDSGKNGQLFYSI-PQGNEEGLFGIFPG-GKLYIRKSLLQALKGSYDLIVRATDGGVPS 1029 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 S++V V I I+D ND +F ++ F ++ENS GT +G + AH D + YS+ Sbjct: 1030 FSASVPVTIYIQDSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYSL 1089 Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY-ELVIRAASPPLWNDVRVE---- 781 + + F+++ R G ++ T V LD E K V + ++ND ++ Sbjct: 1090 ISSE--SHFAVDVRSG----QITTRVRLDREELIKNTGSNVYIMQAEAMYNDTTIKRDKA 1143 Query: 782 ---ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGNN 836 + VTD+NDNAPV + P P R+ A DAD D K Y ++SG Sbjct: 1144 IVIVTVTDLNDNAPVFSRAVYAITVSELSLPGSPVFRIKAMDADEGDNAKFFYSLVSGTG 1203 Query: 837 ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN 874 + +N +TG + LS L+ + V TD N Sbjct: 1204 MDKFFINSSTGELHLSKTLDRETTSSYNLVVKATDASN 1241 Score = 344 bits (846), Expect = 2e-92 Identities = 270/877 (30%), Positives = 413/877 (47%), Gaps = 69/877 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VL+ D+ PVF + Y +V E GT V + AT +D KN + Y I V+ D Sbjct: 729 VTVLNKADNLPVFLYEMYNFTVYENVPKGTLVGRVYATTKD--KNGSISYAI--VSGDPT 784 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N +F +D G + +DRE+ A+Y + V A + V L Sbjct: 785 N-----------------LFLVDSTGGIIKINGDMDREEKAQYLLAVIA--RVGTVKP-L 824 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+ AT+++ ++D NDN PQFS T +V VD D + V+ A D D G N +RY Sbjct: 825 SAQATVNIEVLDRNDNAPQFS--TSSVIVDIDGTWLVGQVVYNAAAVDLDAGKNGLVRYQ 882 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + N + I+S SG + L + L Y + + A D GSP + +T + I + + Sbjct: 883 LTS-NAEGLLWINSTSGVIKLARKLTDGDETQYTVQVLASDSGSPPQHSTMTIHITL-SI 940 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 N + P+F S + V + P+ Y V A D D G N +L Y++ GN + Sbjct: 941 N-HPPKFTLSSYVTHVLASQPLSYQFFYVVAVDQDSGKNGQLFYSIPQ----GNEEGLFG 995 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I P G +Y L + + Y L+V ATDGG P SA+ F+ Sbjct: 996 IFP-GGKLYIRKSLLQALKGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRSLFVNNT 1054 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 + +AE+ PGT V TL A D + ++ F++ ++G+ IT LD Sbjct: 1055 FRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYSLISSESHFAVDVRSGQ--ITTRVRLD 1112 Query: 431 FKQ------ERRYVLTVSA--TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 ++ Y++ A D+ + D A+V + +TD N+ APVF A Y +V E + Sbjct: 1113 REELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVYAITVSELS 1172 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 G+ V + A D+D G NA+ YSL S + +F IN TG + +K LDRE Sbjct: 1173 LPGSPVFRIKAMDADEGDNAKFFYSLVSGTGMD-------KFFINSSTGELHLSKTLDRE 1225 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 T S Y L V A D +L T +EI+V D ND PVF + YT NI EDAL+G+ V Sbjct: 1226 TTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVIN 1285 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 + A+D D+G NG I Y + F ++ A+G + K+LD E+ ++L A D Sbjct: 1286 LNASDKDIGQNGLIKYSIS-NGNLAAMFDVESATGRLIVAKSLDFETTQLYELTITAQDH 1344 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 G P SSTV V + + D+ND+ P+F + +T + EN G +G A D D G NA + Sbjct: 1345 GLIPLSSTVNVTVNVLDVNDNAPLFPTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHI 1404 Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE---SPRKKYELVIRA---ASPPLWN 776 +S+ S +FS+ S E+ T+ +D E + R ++LV+ A SP L Sbjct: 1405 AFSMYSQTPSKTFSV----NSATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLST 1460 Query: 777 DVRVEILVTDVNDNAP-VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGN 835 + + VTD NDN+P + + + + D + K+ Y I+SGN Sbjct: 1461 RKSITVQVTDENDNSPGFVSPPAAAAGSSLNVMTI----TAEDPDRNSNGKVTYSIISGN 1516 Query: 836 NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 N L+ +TG + + Q+ N P + + + +DG Sbjct: 1517 N-GYFNLHPSTGQLQMIHQIPDN-PTIYQLTIQASDG 1551 Score = 294 bits (721), Expect = 3e-77 Identities = 260/919 (28%), Positives = 414/919 (45%), Gaps = 78/919 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ + D ND++PVF +Y AS+ E G +L + ATD D G NA + Y I Sbjct: 624 ELTISDINDNAPVFYPVEYFASIMENEPPGK-LLQVTATDADEGTNAVISYDI---IGGN 679 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N F ID +G + T ASLD E +++++ A D + + Sbjct: 680 NNGN----------------FSIDSSTGVISTLASLDHEVEEFFSLIISAKDGGNKYA-- 721 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + TA ++V +++ DN P F + Y +V E+ V ++ ++ AT D N +I Y Sbjct: 722 -AKTAVVNVTVLNKADNLPVFLYEMYNFTVYEN--VPKGTLVGRVYATTKD--KNGSISY 776 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 AI+ G+ F +DS G + + +D E+ Y L + A+ G S + I + D Sbjct: 777 AIVSGDPTNLFLVDSTGGIIKINGDMDREEKAQYLLAVIARVGTVKPLSAQATVNIEVLD 836 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 NDNAP+F TS + +G + A D D G N + Y +T N + + Sbjct: 837 RNDNAPQFSTSSVIVDIDGTWLVGQVVYNAAAVDLDAGKNGLVRYQLTS-----NAEGLL 891 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 I+ SG + + +L + +Y + V A+D G PP+ +T T F Sbjct: 892 WINSTSGVIKLARKLTDGDETQYTVQVLASDSGSPPQHSTMTIHITLSINHPPK--FTLS 949 Query: 370 QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 Y + +P + A D D ++ +L Y I GN G F I G + + + Sbjct: 950 SYVTHVLASQPLSYQFFYVVAVDQDSGKNGQLFYSIPQGNEEGLFGIFPG---GKLYIRK 1006 Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAMVQINI--TDANNYAPVFENAPYTASVFEDAPIG 485 L + Y L V ATD G S +A V + I D+N++ +F N + +V E++ G Sbjct: 1007 SLLQALKGSYDLIVRATDGGVPSFSASVPVTIYIQDSNDHRSLFVNNTFRFAVAENSSPG 1066 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM- 544 T V + A D I YSL IS+E+ F ++ ++G ITT LDRE + Sbjct: 1067 TLVGTLVAHALDHSRTKDIVYSL---ISSES------HFAVDVRSGQITTRVRLDREELI 1117 Query: 545 -----SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 + Y++ A D V ++V D+NDN PVF + +Y + E +L G+ Sbjct: 1118 KNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVYAITVSELSLPGSP 1177 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 V ++ A DAD G N + Y L + F I+ ++G + +K LDRE+ ++++L A Sbjct: 1178 VFRIKAMDADEGDNAKFFYSLVSGTGMD-KFFINSSTGELHLSKTLDRETTSSYNLVVKA 1236 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 D ST + I + D ND PVF T I+E++ IG+ + + A D D G N Sbjct: 1237 TDASNANLYSTAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQN 1296 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP---PLWN 776 ++ YSI G+ + F +E+ G L+ LD+E+ + YEL I A PL + Sbjct: 1297 GLIKYSISNGNLAAMFDVESATG----RLIVAKSLDFETTQL-YELTITAQDHGLIPLSS 1351 Query: 777 DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSG 834 V V + V DVNDNAP+ + ++ P GR A D D + + + S Sbjct: 1352 TVNVTVNVLDVNDNAPLFPTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQ 1411 Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLN 894 + +N T +T ++ L TM + A Q S +L T + Sbjct: 1412 TPSKTFSVNSATCEITTIAAID-----LETMPAGRDSFQLVVMATDQGSPKLSTRK---- 1462 Query: 895 SITVRLNDM--TAEQFLSP 911 SITV++ D + F+SP Sbjct: 1463 SITVQVTDENDNSPGFVSP 1481 Score = 280 bits (687), Expect = 3e-73 Identities = 214/699 (30%), Positives = 316/699 (45%), Gaps = 36/699 (5%) Query: 199 QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY 258 QF +S +G +S +D E L +R + PS + + + + D+NDN PRF Sbjct: 41 QFGFNSNTGVISTTARIDRETTTQISLQLRTLN---PS-NQPISVQVQVDDINDNEPRFP 96 Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW- 317 T + + E++ + + A D D G N + YT+ D T L T P Sbjct: 97 TLYYTLRIRESMDVNTTNPINTATDPDAGNNGTVDYTIASGDNTATFSLGTTACPTGSTL 156 Query: 318 -VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376 V T LDRET YQL +TATD G P F Y +A Sbjct: 157 CVITKKPLDRETTDFYQLNITATDRGTPALMGYCLINITILDENDHAPVFTQNSYLGSIA 216 Query: 377 EDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434 E+ PG ++ ++A D D + + Y I + + G+I Q LDF+ + Sbjct: 217 ENTKPGVSILRVSAADRDSGSNGDIKYAIDWDAIQSNSIFDLDSSTGVIRTKQNLDFEVK 276 Query: 435 RRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENA---PYT---ASVFEDAPIGT 486 Y V A+D G ++D A V IN+ D N+ +P + P+ A E++ I T Sbjct: 277 NSYTFNVIASDGGVPSKNDLATVTINVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINT 336 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 + + TD D N+Q +++ F I K LDRE + Sbjct: 337 NIAYILVTDKDSNTNSQTELKITNGDDEGCFKVEFLGFYF------IQLQKPLDRELVPF 390 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y LT+ D GVPS S V I V DVNDN P F YTANI E A G+ V Q+ AT Sbjct: 391 YNLTLNVTDKGVPSRSTLGFVLIDVTDVNDNSPAFTSNAYTANISELAQNGSYVLQLNAT 450 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D D G NG + Y + + + G F +D SG++ T K LDRE V++ + A D G+ P Sbjct: 451 DPDEGDNGTVSYSITGGN-DLGWFQVDFQSGLVTTAKPLDREQVSSVTITITAQDHGSAP 509 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 ++ + V + I D ND+ P F ISE + IG T+ ++ A D D G N + Y I Sbjct: 510 KTGSTTVTVTIIDGNDNKPRFMKSSYKGTISEGASIGATVLQVSATDVDSGDNGRITYEI 569 Query: 727 KGGDD--SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVE 781 D + F L T+ G L T LD E+ + Y + A P L + V+VE Sbjct: 570 SSSDAQVNGLFELNTQTGV----LWTKSQLDRET-KSLYSFTVLAKDHGDPQLMSSVKVE 624 Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANL 839 + ++D+NDNAPV + F + + P G +V A DAD + Y I+ GNN Sbjct: 625 LTISDINDNAPVFYPVEY-FASIMENEPPGKLLQVTATDADEGTNAVISYDIIGGNNNGN 683 Query: 840 ILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKA 878 ++ +TG ++ L+ V + ++ +S DG N+ A Sbjct: 684 FSIDSSTGVISTLASLDHEVEEFFSLIISAKDGGNKYAA 722 Score = 252 bits (616), Expect = 1e-64 Identities = 200/692 (28%), Positives = 325/692 (46%), Gaps = 59/692 (8%) Query: 2 SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 SVP I+ Q D NDH +F + +V E +S GT V TL A D + ++ Y+ Sbjct: 1033 SVPVTIYIQ----DSNDHRSLFVNNTFRFAVAENSSPGTLVGTLVAHALDHSRTKDIVYS 1088 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYT---VLVK 118 L+++++ F +D RSG + TR LDRE++ + T V + Sbjct: 1089 --LISSESH-------------------FAVDVRSGQITTRVRLDREELIKNTGSNVYIM 1127 Query: 119 ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178 + + A + V + D NDN P FS Y ++V E +S+ +PV +IKA D Sbjct: 1128 QAEAMYNDTTIKRDKAIVIVTVTDLNDNAPVFSRAVYAITVSE-LSLPGSPVF-RIKAMD 1185 Query: 179 ADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238 AD G N+ Y+++ G +F I+S +G++ L KTLD E SY LV++A D + + Sbjct: 1186 ADEGDNAKFFYSLVSGTGMDKFFINSSTGELHLSKTLDRETTSSYNLVVKATDASNANLY 1245 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 +T ++ I + D ND P F S + +++E+ IG ++ + A D D G N + Y++++ Sbjct: 1246 STAKIEITVGDSNDQRPVFPESDYTVNITEDALIGSLVINLNASDKDIGQNGLIKYSISN 1305 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358 GN+ ++ +G + + LD ET Y+L +TA D G P S+T Sbjct: 1306 ----GNLAAMFDVESATGRLIVAKSLDFETTQLYELTITAQDHGLIPLSSTVNVTVNVLD 1361 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITS 416 F + + E+ G PV TA+D D H + + FS+ S Sbjct: 1362 VNDNAPLFPTQPVTLTVRENVNTGFPVGRCTASDRDTGTNAHIAFSMYSQTPSKTFSVNS 1421 Query: 417 QNGRGLITVAQPLDFKQERR--YVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENA 472 A L+ R + L V ATD G S + + +TD N+ +P F + Sbjct: 1422 ATCEITTIAAIDLETMPAGRDSFQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGFVSP 1481 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 P A A V+ ++A D D N ++TYS+ ++ ++ F ++P TG Sbjct: 1482 PAAA-----AGSSLNVMTITAEDPDRNSNGKVTYSI--------ISGNNGYFNLHPSTGQ 1528 Query: 533 ITT-NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 + +++ D T+ Y LT+ A DGG PS T V + P F Y ++ Sbjct: 1529 LQMIHQIPDNPTI--YQLTIQASDGGQPSRQTQTVVSVFKEGPIGGGPTFSSADYQGSVT 1586 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV- 650 E+ + GTSV V A LNG I Y L D +G F + ++GV++T + +DRE + Sbjct: 1587 ENKVAGTSVVTVLAAYPQSSLNGNIEYYL-TSDSSKGGFEVVKSTGVVKTTRGIDREGMG 1645 Query: 651 ATHDLKAVAID-GGTPPQSSTVIVHIKIEDIN 681 A+ +L A+D G ++S+ V I ++D+N Sbjct: 1646 ASFNLVVYAVDKQGPSARTSSATVTITVQDVN 1677 Score = 244 bits (596), Expect = 4e-62 Identities = 218/789 (27%), Positives = 345/789 (43%), Gaps = 70/789 (8%) Query: 18 DHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXX 77 +H P F + Y V + A DQD GKN ++ Y+I P+ Sbjct: 941 NHPPKFTLSSYVTHVLASQPLSYQFFYVVAVDQDSGKNGQLFYSI---------PQGNE- 990 Query: 78 XXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIH 137 + +F I G L R SL + Y ++V+ATD P S++ + Sbjct: 991 ---------EGLFGIFP-GGKLYIRKSLLQALKGSYDLIVRATDGGVP---SFSASVPVT 1037 Query: 138 VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQ 197 + I D ND+ F T+ +V E+ S ++ + A D I Y++I +++ Sbjct: 1038 IYIQDSNDHRSLFVNNTFRFAVAENSS--PGTLVGTLVAHALDHSRTKDIVYSLI--SSE 1093 Query: 198 MQFSIDSLSGDVSLVKTLDYEQV------RSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251 F++D SG ++ LD E++ Y + A + + + +++ + D+N Sbjct: 1094 SHFAVDVRSGQITTRVRLDREELIKNTGSNVYIMQAEAMYNDTTIKRDKAIVIVTVTDLN 1153 Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311 DNAP F +++ +VSE G + R++A DADEG NA+ Y++ TG +D I Sbjct: 1154 DNAPVFSRAVYAITVSELSLPGSPVFRIKAMDADEGDNAKFFYSLVSG--TG-MD-KFFI 1209 Query: 312 DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371 + +G ++ S LDRET + Y L+V ATD + +TA F Y Sbjct: 1210 NSSTGELHLSKTLDRETTSSYNLVVKATDASNANLYSTAKIEITVGDSNDQRPVFPESDY 1269 Query: 372 EVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 V + ED G+ V+ L A+D D ++ + Y I+ GN F + S GR + VA+ L Sbjct: 1270 TVNITEDALIGSLVINLNASDKDIGQNGLIKYSISNGNLAAMFDVESATGR--LIVAKSL 1327 Query: 430 DFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 DF+ + Y LT++A D G S T V +N+ D N+ AP+F P T +V E+ G Sbjct: 1328 DFETTQLYELTITAQDHGLIPLSSTVNVTVNVLDVNDNAPLFPTQPVTLTVRENVNTGFP 1387 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM--- 544 V +A+D D G NA I +S+ S+ ++ F +N T ITT +D ETM Sbjct: 1388 VGRCTASDRDTGTNAHIAFSMYSQTPSKT-------FSVNSATCEITTIAAIDLETMPAG 1440 Query: 545 -SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 + L V A D G P LS + + V D NDN P F A A +V + Sbjct: 1441 RDSFQLVVMATDQGSPKLSTRKSITVQVTDENDNSPGFVSPPAAA-----AGSSLNVMTI 1495 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 A D D NG++ Y + + G F + P++G ++ + ++ + L A DGG Sbjct: 1496 TAEDPDRNSNGKVTYSIISGNN--GYFNLHPSTGQLQMIHQIP-DNPTIYQLTIQASDGG 1552 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 P + + +V + E P F S ++EN GT++ + A P N + Sbjct: 1553 QPSRQTQTVVSVFKEGPIGGGPTFSSADYQGSVTENKVAGTSVVTVLAAYPQSSLNGNIE 1612 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS----PPLWNDVR 779 Y + F + G K T +D E + LV+ A + Sbjct: 1613 YYLTSDSSKGGFEVVKSTGVVK----TTRGIDREGMGASFNLVVYAVDKQGPSARTSSAT 1668 Query: 780 VEILVTDVN 788 V I V DVN Sbjct: 1669 VTITVQDVN 1677 Score = 172 bits (418), Expect = 1e-40 Identities = 147/512 (28%), Positives = 224/512 (43%), Gaps = 30/512 (5%) Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 Y + E++PPGT V + A E G+ + +F S G+I+ +D Sbjct: 12 YTFHVQEEQPPGTYVGKVDGASAFE----------GSPK-QFGFNSNT--GVISTTARID 58 Query: 431 FKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 +E +++ + VQ+ + D N+ P F YT + E + TT + Sbjct: 59 --RETTTQISLQLRTLNPSNQPISVQVQVDDINDNEPRFPTLYYTLRIRESMDVNTTNPI 116 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550 +ATD D G N + Y+++S N A T + T K LDRET Y L Sbjct: 117 NTATDPDAGNNGTVDYTIASG-DNTATFSLGTTACPTGSTLCVITKKPLDRETTDFYQLN 175 Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610 +TA D G P+L + I+++D ND+ PVF Q Y +I E+ G S+ +V A D D Sbjct: 176 ITATDRGTPALMGYCLINITILDENDHAPVFTQNSYLGSIAENTKPGVSILRVSAADRDS 235 Query: 611 GLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669 G NG I Y +D + S F +D ++GVIRT + LD E ++ +A DGG P ++ Sbjct: 236 GSNGDIKYAIDWDAIQSNSIFDLDSSTGVIRTKQNLDFEVKNSYTFNVIASDGGVPSKND 295 Query: 670 TVIVHIKIEDINDSPPVFESDCLTFY------ISENSPIGTTIGEIRAHDPDEGPNAVVH 723 V I + D ND+ P + L + SENS I T I I D D N+ Sbjct: 296 LATVTINVLDTNDNSPQLKITYLPPHNGDKAIRSENSLINTNIAYILVTDKDSNTNSQTE 355 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR-VEI 782 I GDD F +E G +L +D + P L + P + + V I Sbjct: 356 LKITNGDDEGCFKVEF-LGFYFIQLQKPLDREL-VPFYNLTLNVTDKGVPSRSTLGFVLI 413 Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVTDK--LQYRILSGNNANL 839 VTDVNDN+P N + G + ++ A D D D + Y I GN+ Sbjct: 414 DVTDVNDNSPAFTS-NAYTANISELAQNGSYVLQLNATDPDEGDNGTVSYSITGGNDLGW 472 Query: 840 ILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 ++ +G +T + L+ T+ ++ D Sbjct: 473 FQVDFQSGLVTTAKPLDREQVSSVTITITAQD 504 >UniRef50_UPI00006A0F33 Cluster: dachsous 2 isoform 1; n=1; Xenopus tropicalis|Rep: dachsous 2 isoform 1 - Xenopus tropicalis Length = 2787 Score = 372 bits (914), Expect = e-100 Identities = 272/902 (30%), Positives = 436/902 (48%), Gaps = 63/902 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++++ D ND+ P+F + A + E G ++ ++ A+D D G NA++ Y+I + Sbjct: 1308 KLDISDVNDNPPMFVKSTFVAYLPENNLPGASIYSIHASDPDYGNNAKIIYSISNIVGTV 1367 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 D+ GR ++T+++LDREK A Y + + ATD+ SP + Sbjct: 1368 PFQLDSST----------------GRFYRIVTKSALDREKTALYNITIVATDKGSP---Q 1408 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LSS I ++I D NDN P F + + E+ + I +I+A+D D G N+ + Y Sbjct: 1409 LSSRKFIRLDISDVNDNPPVFMKSKDVAYLPENNLPGSS--IYRIQASDLDTGDNAKVIY 1466 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 +I + + F I S + L K LD E + L++ A DGG+P RS T + I + D Sbjct: 1467 SISSMDNE-DFPISSYFSKLVLEKPLDRETQTIHELILTASDGGNPVRSGTALIRIAVTD 1525 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 NDN P F +++ S+SEN+PI +++ V A D DEG NA++ Y+ ++ N++ Sbjct: 1526 SNDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQIMYSFRSSFFSINIE--- 1582 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM-P 368 +G +Y D E ++Q+ V A D G P S A+ + P Sbjct: 1583 -----TGVLYAQRSFDYEQHKEFQIKVYAKDYGSPSLSCNASLTIRITDQNDNVPKILYP 1637 Query: 369 GQYEVELAEDEPP-----GTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRG 421 V+ + + P G + + A DAD + L Y + G+ FSI SQN Sbjct: 1638 SSESVDSSFEMVPVASEQGALITKVVAVDADSGHNAWLSYHVVQGSEPSLFSI-SQNTGE 1696 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVF 479 + T +PLD + + + L ++A+D G RS TA+++I +TDAN+ PVF Y S+ Sbjct: 1697 IRTSQKPLDRETQTIHELILTASDGGNPVRSGTALIRIAVTDANDNLPVFTQEVYKVSIT 1756 Query: 480 ---EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 ED+P GT + ++ D D G N +I L + + + + I ITT Sbjct: 1757 IIPEDSPSGTLIALIEVHDQDSGENGEIDCQLLGTGPFQLLLSSTKYYRI------ITTG 1810 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 LDRE + Y +T+ A D G P LS+ +++ + DVNDN PVF + Y A I E+ L Sbjct: 1811 S-LDREKVPWYNITIQATDRGSPHLSNIKLIKLDISDVNDNAPVFTKSSYVAYIAENNLA 1869 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN-KALDRESVATHDL 655 G S+ ++ A+D D G N +I Y + + E F I +G IR++ K LDRE+ H+L Sbjct: 1870 GASIYRIQASDIDAGDNAKIIYSI--YNTEPSPFSISQHTGEIRSSQKPLDRETQKDHEL 1927 Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 A DGG P ++ T I+ I + D ND+ PVF ISEN PI +++ + A D D Sbjct: 1928 ILTASDGGDPVKTGTAIIRIIVTDANDNLPVFTKAVYKVSISENIPINSSVLHVNATDRD 1987 Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW 775 EG NA + YS +++ S E+ T+ LD+E R YE+ ++A + Sbjct: 1988 EGTNAQITYSFIKTSENDIHSPMFSINQINGEIKTLQKLDFELTR-NYEMSVQATDGGGF 2046 Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILS 833 + + ++DVNDN PV + I ++ P +V A D D K+ Y + + Sbjct: 2047 VAKSILLDISDVNDNPPVFLKSRYIAYLPENNLPGASIYKVQASDLDTGENSKVIYSVFN 2106 Query: 834 GNN-----ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLI 887 N ++ +N TG + + K M V D G + + L +R+I Sbjct: 2107 TNTEAFPVSSYFSINIETGVLYAQRSFDYEQHKEFAMHVQAKDNGYPSLSSNATLIIRII 2166 Query: 888 TE 889 + Sbjct: 2167 DQ 2168 Score = 363 bits (893), Expect = 4e-98 Identities = 275/881 (31%), Positives = 427/881 (48%), Gaps = 76/881 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I V D ND+ PVF Y+ S+ E ++VL + ATD+D G NA++ Y+ + + Sbjct: 1946 RIIVTDANDNLPVFTKAVYKVSISENIPINSSVLHVNATDRDEGTNAQITYSFIKTSEND 2005 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 ++ +F I+ +G + T LD E Y + V+ATD V+ Sbjct: 2006 IH---------------SPMFSINQINGEIKTLQKLDFELTRNYEMSVQATDGGGFVAK- 2049 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 +I ++I D NDN P F + Y + E+ I K++A+D D G NS + Y Sbjct: 2050 -----SILLDISDVNDNPPVFLKSRYIAYLPENN--LPGASIYKVQASDLDTGENSKVIY 2102 Query: 190 AIIGGNTQM-----QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 ++ NT+ FSI+ +G + ++ DYEQ + + + ++A+D G PS S+ L+ Sbjct: 2103 SVFNTNTEAFPVSSYFSINIETGVLYAQRSFDYEQHKEFAMHVQAKDNGYPSLSSNATLI 2162 Query: 245 INIRDVNDNAPRFYTSLFQESVS---ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 I I D NDNAP+ + S S E VP + A D D G N+ TY ++D Y Sbjct: 2163 IRIIDQNDNAPKILYPSTENSDSLIFEMVPFAST-----AEDPDIGSNSVQTYKLSDNQY 2217 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 + + + + LDRET+ ++LL+TA+DGG P R+ TA Sbjct: 2218 FTLNEKTSSDGSKFPELVLERPLDRETKNIHELLLTASDGGTPVRTGTALIRVIVTDAND 2277 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421 F Y+V ++E+ P + V+ + A+D DE + T FS+ +NG Sbjct: 2278 NTPVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSKYFSVDLENGNL 2337 Query: 422 L-ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASV 478 + + +PLD + + + L ++A+D G R+ TA++++ +TDAN+ PVF Y S+ Sbjct: 2338 YELVLERPLDREIKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSI 2397 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA------ 532 E+ PI +TVL V+A+D D G NAQITYS S N H F INP +G Sbjct: 2398 SENTPINSTVLRVNASDMDEGTNAQITYSFSRTSENSL---HASMFSINPTSGEMNEKTS 2454 Query: 533 --------ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584 + + LDRET + + L +TA DGG P + T + + V D NDN PVF Q+ Sbjct: 2455 SDGSKFPELVLERPLDRETKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQE 2514 Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP---KDREEGSFVIDPASGVIRT 641 +Y +I E+ + ++V +V A+D D G N +I Y F I+P SG I T Sbjct: 2515 VYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEITT 2574 Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVI-VHIKIEDINDSPPVFESDCLTFYISENS 700 N L+ E+ +++ A DGG S V V I+I+DIND+ P F T ISEN+ Sbjct: 2575 NNLLNFEAKKDYEISVQAKDGGGFVAHSKVFPVIIEIQDINDNAPKFFPVLYTVSISENT 2634 Query: 701 PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760 +G+ + + A D DEG NA + YS +S+ E+ T L++E R Sbjct: 2635 AVGSVVLCVNATDKDEGINAQITYSFSKTSESSLNKSMFSINPTTGEIKTEKQLNFEGTR 2694 Query: 761 KKYELVIRAASPPLW-NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY 819 YEL ++A + +V I +TD NDNAP + + +D P + + Sbjct: 2695 N-YELSVQAKDGGGFVTHSKVLIEITDENDNAPEISIASLSTPVPEDSAPGSVIALIEVH 2753 Query: 820 DADVTDKLQYRILSGNNANLIL-LNETTGSMTLSPQLNTNV 859 D D SG+NA + ++ET T+SP + N+ Sbjct: 2754 DQD----------SGSNAKITYSISETN---TMSPYFSINI 2781 Score = 359 bits (884), Expect = 5e-97 Identities = 266/909 (29%), Positives = 439/909 (48%), Gaps = 82/909 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I + D NDH P+F + Y+ S+ E TTVL + ATD+D G NA++ Y++ + D+ Sbjct: 861 RIAITDVNDHIPMFTQEVYKVSISESIPINTTVLQVNATDKDEGVNAQITYSLIRTSGDS 920 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD- 128 L F I+ SG + T+ +L+ E Y + V+A D A+ + Sbjct: 921 L---------------ASATFSINPASGEIKTKRNLNFEVQKHYEMSVEAKDGATDGGNP 965 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 + + TA + + + D NDN P F+++ Y +S+ E + N + + ATD D G N I Sbjct: 966 KRTGTALLRIIVTDYNDNVPVFTQQVYKISISESAPI--NSTVTVVTATDKDDGTNGHIT 1023 Query: 189 YAII-----GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 Y+ +TQM F+I+ +G++ ++ DYEQ + +++ I A+D GSP S+ L Sbjct: 1024 YSFSRTAENAFHTQM-FNINPANGEIKTKRSFDYEQHKEFQINIMAKDNGSPPLSSNATL 1082 Query: 244 LINIRDVNDNAPRFYTSLFQESVS---ENVPI----GYSIVRVQAYDADEGVNAELTYTM 296 +I+I D NDNAP+ + S E VP G I ++ A D D G NA++ Y++ Sbjct: 1083 IIHIIDQNDNAPKILYPSTESGGSPFFEMVPFASVQGSLITKIHASDPDAGDNAKIIYSI 1142 Query: 297 TDKDYTGNVDLPI----TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT- 351 ++ D P+ +I+ +G +Y D E ++Q+ ++A D G PP S+ T Sbjct: 1143 SN---INTEDFPVSPYFSINIETGVLYAQRSFDYEQHKEFQMKISAKDNGSPPLSSNVTL 1199 Query: 352 --XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGN 407 ED PGT + + D D E+ + +I G + Sbjct: 1200 IIHIIEIMDENDNAPEISIRSLSTPFPEDSAPGTLIALIEVHDQDSGENGEVECQIIGPS 1259 Query: 408 TRGRFSITSQNGRGL-ITVAQPLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANN 464 F + S + R I LD + Y +T+ ATD G + M ++++I+D N+ Sbjct: 1260 P---FQLLSSSSRYYKIVNTGSLDRELVPWYNITILATDRGSPQLSTMKFIKLDISDVND 1316 Query: 465 YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524 P+F + + A + E+ G ++ + A+D D G NA+I YS+S+ + F Sbjct: 1317 NPPMFVKSTFVAYLPENNLPGASIYSIHASDPDYGNNAKIIYSISNIVGT-------VPF 1369 Query: 525 VINPQTG---AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581 ++ TG I T LDRE + Y +T+ A D G P LS + + + DVNDN PVF Sbjct: 1370 QLDSSTGRFYRIVTKSALDREKTALYNITIVATDKGSPQLSSRKFIRLDISDVNDNPPVF 1429 Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641 + A + E+ L G+S+ ++ A+D D G N ++ Y + D E+ F I + Sbjct: 1430 MKSKDVAYLPENNLPGSSIYRIQASDLDTGDNAKVIYSISSMDNED--FPISSYFSKLVL 1487 Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701 K LDRE+ H+L A DGG P +S T ++ I + D ND+ PVF + ISEN P Sbjct: 1488 EKPLDRETQTIHELILTASDGGNPVRSGTALIRIAVTDSNDNLPVFTQEVYKVSISENIP 1547 Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761 I +T+ + A D DEG NA + YS + S+ FS+ G L DYE K Sbjct: 1548 INSTVLTVNATDRDEGTNAQIMYSFR----SSFFSINIETG----VLYAQRSFDYEQ-HK 1598 Query: 762 KYELVIRA---ASPPLWNDVRVEILVTDVNDNAP-VMKDFQIIFNNYKDCFPVGP----- 812 ++++ + A SP L + + I +TD NDN P ++ ++ + PV Sbjct: 1599 EFQIKVYAKDYGSPSLSCNASLTIRITDQNDNVPKILYPSSESVDSSFEMVPVASEQGAL 1658 Query: 813 FGRVPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTLSPQ-LNTNVPKLATMEVSV 869 +V A DAD L Y ++ G+ +L +++ TG + S + L+ + + ++ Sbjct: 1659 ITKVVAVDADSGHNAWLSYHVVQGSEPSLFSISQNTGEIRTSQKPLDRETQTIHELILTA 1718 Query: 870 TDGVNEIKA 878 +DG N +++ Sbjct: 1719 SDGGNPVRS 1727 Score = 356 bits (875), Expect = 6e-96 Identities = 276/907 (30%), Positives = 447/907 (49%), Gaps = 88/907 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVR---EGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 +I V D ND+ PVF + Y+ S+ E + SGT + ++ DQD G+N E++ + L T Sbjct: 1733 RIAVTDANDNLPVFTQEVYKVSITIIPEDSPSGTLIALIEVHDQDSGENGEIDCQL-LGT 1791 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 P +RI +T SLDREKV Y + ++ATD+ SP Sbjct: 1792 G----PFQLLLSSTKY-------YRI-------ITTGSLDREKVPWYNITIQATDRGSP- 1832 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 LS+ I ++I D NDN P F++ +Y + E+ + I +I+A+D D G N+ Sbjct: 1833 --HLSNIKLIKLDISDVNDNAPVFTKSSYVAYIAENNLAGAS--IYRIQASDIDAGDNAK 1888 Query: 187 IRYAIIGGNTQMQ-FSIDSLSGDV-SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 I Y+I NT+ FSI +G++ S K LD E + + L++ A DGG P ++ T + Sbjct: 1889 IIYSIY--NTEPSPFSISQHTGEIRSSQKPLDRETQKDHELILTASDGGDPVKTGTAIIR 1946 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 I + D NDN P F ++++ S+SEN+PI S++ V A D DEG NA++TY+ K + Sbjct: 1947 IIVTDANDNLPVFTKAVYKVSISENIPINSSVLHVNATDRDEGTNAQITYSFI-KTSEND 2005 Query: 305 VDLPI-TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 + P+ +I+ +G + T +LD E Y++ V ATDGG + Sbjct: 2006 IHSPMFSINQINGEIKTLQKLDFELTRNYEMSVQATDGGG---FVAKSILLDISDVNDNP 2062 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG-- 419 F+ +Y L E+ PG + + A+D D E++++ Y + NT F ++S Sbjct: 2063 PVFLKSRYIAYLPENNLPGASIYKVQASDLDTGENSKVIYSVFNTNTEA-FPVSSYFSIN 2121 Query: 420 --RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAP--VFENAP 473 G++ + D++Q + + + V A D+G S A + I I D N+ AP ++ + Sbjct: 2122 IETGVLYAQRSFDYEQHKEFAMHVQAKDNGYPSLSSNATLIIRIIDQNDNAPKILYPSTE 2181 Query: 474 YTAS-VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 + S +FE P +T A D D+G N+ TY LS N+ +++ + Sbjct: 2182 NSDSLIFEMVPFAST-----AEDPDIGSNSVQTYKLSD---NQYFTLNEKTSSDGSKFPE 2233 Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592 + + LDRET + + L +TA DGG P + T + + V D NDN PVF Q++Y +I E Sbjct: 2234 LVLERPLDRETKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISE 2293 Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT---NKALDRES 649 + + ++V +V A+D D G N +I Y R F +D +G + + LDRE Sbjct: 2294 NTPINSTVLRVNASDMDEGTNAQITYSFS---RTSKYFSVDLENGNLYELVLERPLDREI 2350 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 H+L A DGGTP ++ T ++ + + D ND+ PVF + ISEN+PI +T+ + Sbjct: 2351 KNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISENTPINSTVLRV 2410 Query: 710 RAHDPDEGPNAVVHYSIKGGDDSN----SFSLE----------TRQGSDKAELVTMVDLD 755 A D DEG NA + YS +++ FS+ + GS ELV LD Sbjct: 2411 NASDMDEGTNAQITYSFSRTSENSLHASMFSINPTSGEMNEKTSSDGSKFPELVLERPLD 2470 Query: 756 YESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-G 811 E+ + +EL++ A+ +P + ++VTD NDN PV ++ + + P+ Sbjct: 2471 RET-KNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQ-EVYKVSISENTPINS 2528 Query: 812 PFGRVPAYDAD------VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATM 865 RV A D D +T ++ +A++ +N T+G +T + LN K + Sbjct: 2529 TVLRVNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEITTNNLLNFEAKKDYEI 2588 Query: 866 EVSVTDG 872 V DG Sbjct: 2589 SVQAKDG 2595 Score = 354 bits (871), Expect = 2e-95 Identities = 260/867 (29%), Positives = 410/867 (47%), Gaps = 59/867 (6%) Query: 12 NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71 +V D ND+ P+F + Y S+ E G+ + + A+D+D GKNA++ Y Sbjct: 334 SVDDINDNPPLFTEELYFFSIAENILPGSLIFQVSASDKDSGKNAQLLY----------- 382 Query: 72 PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131 A V I+ SG + + S D EK+ + + V TD +P LS Sbjct: 383 ---ALLESYVEGMSVSHFISINPDSGNVFSVDSFDYEKIPQKNITVTVTDSGTPP---LS 436 Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191 + T++V + D NDN P F EK+Y++ + E+ + + +KATD D NS + Y++ Sbjct: 437 TQKTLYVEVSDLNDNPPTFEEKSYSIYIMENNA--PGVSLISVKATDLDSNENSFVSYSL 494 Query: 192 IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251 + + F ++ +G++ LD E Y + I + D GSP S + +NI DVN Sbjct: 495 LRASDPKLFQVELHTGEIRTTSFLDRENTSQYNITILSTDRGSPKLSTVKHIRLNISDVN 554 Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311 DNAP F S + +SEN G SI R+ AYD D G NA++ Y++ N+ I Sbjct: 555 DNAPIFKKSTYVAYLSENNLPGSSIYRINAYDPDTGDNAKIIYSIAGT----NIKSTFDI 610 Query: 312 DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371 +P SG + T LD E+ Y++ + A DGG A Sbjct: 611 NPTSGKITTKRDLDFESVQSYEIAIEAMDGGG--FVAQTKVLIEIIDENDNAPEISIASL 668 Query: 372 EVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGL-ITVAQP 428 + ED PGT + + D D + + +I G F I S + R I A Sbjct: 669 SAPIPEDSMPGTVIALIKVHDQDTGRNGEVDCQILGA---APFQIVSSSSRYYRIITASF 725 Query: 429 LDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD ++ Y +T+ ATD G S T ++++++D N+ PVF Y A + E+ G+ Sbjct: 726 LDREKVPWYNITILATDKGSPELSSTKSIKLDLSDVNDNPPVFSKPTYVAYLPENNLPGS 785 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG--AITTNKLLDRETM 544 ++ + A D D G NA++ YS+ + F IN TG + K LDRE + Sbjct: 786 SIYRIQAFDFDSGNNAKVVYSI--------LMSDPSPFSINQYTGEHKVVIMKPLDRENL 837 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 + L +TA DGG P + T + I++ DVND+ P+F Q++Y +I E + T+V QV Sbjct: 838 KIHKLLLTAFDGGNPVRTGTALIRIAITDVNDHIPMFTQEVYKVSISESIPINTTVLQVN 897 Query: 605 ATDADVGLNGRIHYEL---DPKDREEGSFVIDPASGVIRTNKALDRESVATHDL----KA 657 ATD D G+N +I Y L +F I+PASG I+T + L+ E +++ K Sbjct: 898 ATDKDEGVNAQITYSLIRTSGDSLASATFSINPASGEIKTKRNLNFEVQKHYEMSVEAKD 957 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A DGG P ++ T ++ I + D ND+ PVF ISE++PI +T+ + A D D+G Sbjct: 958 GATDGGNPKRTGTALLRIIVTDYNDNVPVFTQQVYKISISESAPINSTVTVVTATDKDDG 1017 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPL 774 N + YS ++ + E+ T DYE K++++ I A SPPL Sbjct: 1018 TNGHITYSFSRTAENAFHTQMFNINPANGEIKTKRSFDYEQ-HKEFQINIMAKDNGSPPL 1076 Query: 775 WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSG 834 ++ + I + D NDNAP + + + F + PF V + +T +G Sbjct: 1077 SSNATLIIHIIDQNDNAPKIL-YPSTESGGSPFFEMVPFASVQG--SLITKIHASDPDAG 1133 Query: 835 NNANLI--LLNETTGSMTLSPQLNTNV 859 +NA +I + N T +SP + N+ Sbjct: 1134 DNAKIIYSISNINTEDFPVSPYFSINI 1160 Score = 353 bits (869), Expect = 3e-95 Identities = 261/897 (29%), Positives = 433/897 (48%), Gaps = 62/897 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I ++D ND++P + A + E + GT + +K DQD G+N EV+ I Sbjct: 651 IEIIDENDNAPEISIASLSAPIPEDSMPGTVIALIKVHDQDTGRNGEVDCQI-------- 702 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + R ++T + LDREKV Y + + ATD+ SP L Sbjct: 703 -----------LGAAPFQIVSSSSRYYRIITASFLDREKVPWYNITILATDKGSP---EL 748 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SST +I +++ D NDN P FS+ TY + E+ + I +I+A D D G N+ + Y+ Sbjct: 749 SSTKSIKLDLSDVNDNPPVFSKPTYVAYLPENNLPGSS--IYRIQAFDFDSGNNAKVVYS 806 Query: 191 IIGGNTQMQFSIDSLSGD--VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 I+ + FSI+ +G+ V ++K LD E ++ ++L++ A DGG+P R+ T + I I Sbjct: 807 ILMSDPS-PFSINQYTGEHKVVIMKPLDRENLKIHKLLLTAFDGGNPVRTGTALIRIAIT 865 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 DVND+ P F +++ S+SE++PI ++++V A D DEGVNA++TY++ Sbjct: 866 DVNDHIPMFTQEVYKVSISESIPINTTVLQVNATDKDEGVNAQITYSLIRTSGDSLASAT 925 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVT----ATDGGDPPRSATATXXXXXXXXXXXXX 364 +I+P SG + T L+ E Q Y++ V ATDGG+P R+ TA Sbjct: 926 FSINPASGEIKTKRNLNFEVQKHYEMSVEAKDGATDGGNPKRTGTALLRIIVTDYNDNVP 985 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGR------FSITSQN 418 F Y++ ++E P + V +TATD D+ H + T F+I N Sbjct: 986 VFTQQVYKISISESAPINSTVTVVTATDKDDGTNGHITYSFSRTAENAFHTQMFNINPAN 1045 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAP--VFENAPY 474 G I + D++Q + + + + A D+G S A + I+I D N+ AP ++ + Sbjct: 1046 GE--IKTKRSFDYEQHKEFQINIMAKDNGSPPLSSNATLIIHIIDQNDNAPKILYPSTES 1103 Query: 475 TAS-VFEDAPI----GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 S FE P G+ + + A+D D G NA+I YS+S+ I+ E F IN + Sbjct: 1104 GGSPFFEMVPFASVQGSLITKIHASDPDAGDNAKIIYSISN-INTEDFP-VSPYFSINIE 1161 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV---NDNEPVFKQQLY 586 TG + + D E + + ++A+D G P LS + I ++++ NDN P + Sbjct: 1162 TGVLYAQRSFDYEQHKEFQMKISAKDNGSPPLSSNVTLIIHIIEIMDENDNAPEISIRSL 1221 Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646 + ED+ GT ++ + D D G NG + ++ + ++ T +LD Sbjct: 1222 STPFPEDSAPGTLIALIEVHDQDSGENGEVECQIIGPSPFQLLSSSSRYYKIVNTG-SLD 1280 Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706 RE V +++ +A D G+P S+ + + I D+ND+PP+F Y+ EN+ G +I Sbjct: 1281 RELVPWYNITILATDRGSPQLSTMKFIKLDISDVNDNPPMFVKSTFVAYLPENNLPGASI 1340 Query: 707 GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV 766 I A DPD G NA + YSI + F L++ G +VT LD E Y + Sbjct: 1341 YSIHASDPDYGNNAKIIYSISNIVGTVPFQLDSSTGR-FYRIVTKSALDREK-TALYNIT 1398 Query: 767 IRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV 823 I A SP L + + + ++DVNDN PV + + ++ P R+ A D D Sbjct: 1399 IVATDKGSPQLSSRKFIRLDISDVNDNPPVFMKSKDVAYLPENNLPGSSIYRIQASDLDT 1458 Query: 824 TD--KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKA 878 D K+ Y I S +N + ++ + L L+ + + ++ +DG N +++ Sbjct: 1459 GDNAKVIYSISSMDNED-FPISSYFSKLVLEKPLDRETQTIHELILTASDGGNPVRS 1514 Score = 353 bits (867), Expect = 5e-95 Identities = 250/761 (32%), Positives = 379/761 (49%), Gaps = 58/761 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +++ D ND+ PVF +Y A + E G ++ ++A+D D G+N++V Y++ + Sbjct: 2053 LDISDVNDNPPVFLKSRYIAYLPENNLPGASIYKVQASDLDTGENSKVIYSVFNTNTEAF 2112 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 V F I+ +G L + S D E+ + + V+A D P L Sbjct: 2113 P--------------VSSYFSINIETGVLYAQRSFDYEQHKEFAMHVQAKDNGYP---SL 2155 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SS AT+ + IID NDN P+ Y + + D + + A A D D+G+NS Y Sbjct: 2156 SSNATLIIRIIDQNDNAPKI---LYPSTENSDSLIFEMVPFAST-AEDPDIGSNSVQTYK 2211 Query: 191 IIGGN----TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 + + S S ++ L + LD E + L++ A DGG+P R+ T + + Sbjct: 2212 LSDNQYFTLNEKTSSDGSKFPELVLERPLDRETKNIHELLLTASDGGTPVRTGTALIRVI 2271 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + D NDN P F +++ S+SEN PI +++RV A D DEG NA++TY+ + +VD Sbjct: 2272 VTDANDNTPVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSKYFSVD 2331 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 L + + LDRE + ++LL+TA+DGG P R+ TA F Sbjct: 2332 LE---NGNLYELVLERPLDREIKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVF 2388 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADE--------------DNRLHYEITGGN-TRGR 411 Y+V ++E+ P + V+ + A+D DE +N LH + N T G Sbjct: 2389 TQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSENSLHASMFSINPTSGE 2448 Query: 412 FS-ITSQNGRGL--ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYA 466 + TS +G + + +PLD + + + L ++A+D G R+ TA++++ +TDAN+ Sbjct: 2449 MNEKTSSDGSKFPELVLERPLDRETKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNT 2508 Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 PVF Y S+ E+ PI +TVL V+A+D D G NAQITYS S N H F I Sbjct: 2509 PVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSVNSL---HASMFSI 2565 Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585 NP +G ITTN LL+ E Y ++V A+D GG + S V I + D+NDN P F L Sbjct: 2566 NPTSGEITTNNLLNFEAKKDYEISVQAKDGGGFVAHSKVFPVIIEIQDINDNAPKFFPVL 2625 Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR---EEGSFVIDPASGVIRTN 642 YT +I E+ VG+ V V ATD D G+N +I Y + F I+P +G I+T Sbjct: 2626 YTVSISENTAVGSVVLCVNATDKDEGINAQITYSFSKTSESSLNKSMFSINPTTGEIKTE 2685 Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 K L+ E ++L A DGG S V+ I+I D ND+ P L+ + E+S Sbjct: 2686 KQLNFEGTRNYELSVQAKDGGGFVTHSKVL--IEITDENDNAPEISIASLSTPVPEDSAP 2743 Query: 703 GTTIGEIRAHDPDEGPNAVVHYSIKGGDD-SNSFSLETRQG 742 G+ I I HD D G NA + YSI + S FS+ G Sbjct: 2744 GSVIALIEVHDQDSGSNAKITYSISETNTMSPYFSINIETG 2784 Score = 349 bits (858), Expect = 7e-94 Identities = 239/806 (29%), Positives = 386/806 (47%), Gaps = 62/806 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASS-----GTTVLTLKATDQDIGKNAEVEYTIELV 65 + V+D ND++P + V E A+ G+ + T+ A+D D G+N+ + Y++ Sbjct: 220 VTVVDVNDNAPEMTVTSLSLPVPEDATHENNPPGSHIYTVSASDSDTGQNSFITYSLRSG 279 Query: 66 TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125 + + ++ +L+ + +LDRE VA Y V + ATD P Sbjct: 280 SGNQTYSLNSKFSNYY----------------SLVLKDNLDRESVAEYNVPISATDNGIP 323 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 LS+TA I+ ++ D NDN P F+E+ Y S+ E+I +I ++ A+D D G N+ Sbjct: 324 A---LSTTAYIYFSVDDINDNPPLFTEELYFFSIAENI--LPGSLIFQVSASDKDSGKNA 378 Query: 186 AIRYAII-----GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240 + YA++ G + SI+ SG+V V + DYE++ + + D G+P S Sbjct: 379 QLLYALLESYVEGMSVSHFISINPDSGNVFSVDSFDYEKIPQKNITVTVTDSGTPPLSTQ 438 Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 L + + D+NDN P F + + EN G S++ V+A D D N+ ++Y++ Sbjct: 439 KTLYVEVSDLNDNPPTFEEKSYSIYIMENNAPGVSLISVKATDLDSNENSFVSYSL---- 494 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 + ++ +G + T+ LDRE ++Y + + +TD G P S Sbjct: 495 LRASDPKLFQVELHTGEIRTTSFLDRENTSQYNITILSTDRGSPKLSTVKHIRLNISDVN 554 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRGRFSITSQN 418 F Y L+E+ PG+ + + A D D DN ++ Y I G N + F I + Sbjct: 555 DNAPIFKKSTYVAYLSENNLPGSSIYRINAYDPDTGDNAKIIYSIAGTNIKSTFDINPTS 614 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASV 478 G+ IT + LDF+ + Y + + A D GG V I I D N+ AP A +A + Sbjct: 615 GK--ITTKRDLDFESVQSYEIAIEAMDGGGFVAQTKVLIEIIDENDNAPEISIASLSAPI 672 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 ED+ GT + ++ D D G N ++ + + V+ + + I T Sbjct: 673 PEDSMPGTVIALIKVHDQDTGRNGEVDCQILGAAPFQIVSSSSRYY-------RIITASF 725 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 LDRE + Y +T+ A D G P LS T +++ + DVNDN PVF + Y A + E+ L G+ Sbjct: 726 LDREKVPWYNITILATDKGSPELSSTKSIKLDLSDVNDNPPVFSKPTYVAYLPENNLPGS 785 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 S+ ++ A D D G N ++ Y + D S + K LDRE++ H L Sbjct: 786 SIYRIQAFDFDSGNNAKVVYSILMSDPSPFSINQYTGEHKVVIMKPLDRENLKIHKLLLT 845 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 A DGG P ++ T ++ I I D+ND P+F + ISE+ PI TT+ ++ A D DEG Sbjct: 846 AFDGGNPVRTGTALIRIAITDVNDHIPMFTQEVYKVSISESIPINTTVLQVNATDKDEGV 905 Query: 719 NAVVHYSI--KGGDD--SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA----- 769 NA + YS+ GD S +FS+ G E+ T +L++E +K YE+ + A Sbjct: 906 NAQITYSLIRTSGDSLASATFSINPASG----EIKTKRNLNFE-VQKHYEMSVEAKDGAT 960 Query: 770 --ASPPLWNDVRVEILVTDVNDNAPV 793 +P + I+VTD NDN PV Sbjct: 961 DGGNPKRTGTALLRIIVTDYNDNVPV 986 Score = 340 bits (835), Expect = 4e-91 Identities = 255/815 (31%), Positives = 387/815 (47%), Gaps = 68/815 (8%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 H ++N+ D ND++P+F+ Y A + E G+++ + A D D G NA++ Y+I Sbjct: 545 HIRLNISDVNDNAPIFKKSTYVAYLSENNLPGSSIYRINAYDPDTGDNAKIIYSI----- 599 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 ++ F I+ SG + T+ LD E V Y + ++A D V+ Sbjct: 600 --------------AGTNIKSTFDINPTSGKITTKRDLDFESVQSYEIAIEAMDGGGFVA 645 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 + + IID+NDN P+ S + + + ED VIA IK D D G N + Sbjct: 646 Q-----TKVLIEIIDENDNAPEISIASLSAPIPED--SMPGTVIALIKVHDQDTGRNGEV 698 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 I+G S S + LD E+V Y + I A D GSP S+T + +++ Sbjct: 699 DCQILGAAPFQIVSSSSRYYRIITASFLDREKVPWYNITILATDKGSPELSSTKSIKLDL 758 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 DVNDN P F + + EN G SI R+QA+D D G NA++ Y++ D + Sbjct: 759 SDVNDNPPVFSKPTYVAYLPENNLPGSSIYRIQAFDFDSGNNAKVVYSILMSDPS----- 813 Query: 308 PITIDPRSG--WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 P +I+ +G V LDRE ++LL+TA DGG+P R+ TA Sbjct: 814 PFSINQYTGEHKVVIMKPLDRENLKIHKLLLTAFDGGNPVRTGTALIRIAITDVNDHIPM 873 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI--TGGNTRGRFSITSQNGRG 421 F Y+V ++E P T V+ + ATD DE + ++ Y + T G++ + + G Sbjct: 874 FTQEVYKVSISESIPINTTVLQVNATDKDEGVNAQITYSLIRTSGDSLASATFSINPASG 933 Query: 422 LITVAQPLDFKQERRYVLTVSATD---SGG---RSDTAMVQINITDANNYAPVFENAPYT 475 I + L+F+ ++ Y ++V A D GG R+ TA+++I +TD N+ PVF Y Sbjct: 934 EIKTKRNLNFEVQKHYEMSVEAKDGATDGGNPKRTGTALLRIIVTDYNDNVPVFTQQVYK 993 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 S+ E API +TV VV+ATD D G N ITYS S N A H Q F INP G I T Sbjct: 994 ISISESAPINSTVTVVTATDKDDGTNGHITYSFSRTAEN---AFHTQMFNINPANGEIKT 1050 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ-------QLYTA 588 + D E + + + A+D G P LS + I ++D NDN P + Sbjct: 1051 KRSFDYEQHKEFQINIMAKDNGSPPLSSNATLIIHIIDQNDNAPKILYPSTESGGSPFFE 1110 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE----GSFVIDPASGVIRTNKA 644 + ++ G+ ++++ A+D D G N +I Y + + E+ F I+ +GV+ ++ Sbjct: 1111 MVPFASVQGSLITKIHASDPDAGDNAKIIYSISNINTEDFPVSPYFSINIETGVLYAQRS 1170 Query: 645 LDRESVATHDLKAVAIDGGTPPQSS--TVIVH-IKIEDINDSPPVFESDCLTFYISENSP 701 D E +K A D G+PP SS T+I+H I+I D ND+ P L+ E+S Sbjct: 1171 FDYEQHKEFQMKISAKDNGSPPLSSNVTLIIHIIEIMDENDNAPEISIRSLSTPFPEDSA 1230 Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761 GT I I HD D G N V I G S +R ++V LD E Sbjct: 1231 PGTLIALIEVHDQDSGENGEVECQIIGPSPFQLLSSSSRY----YKIVNTGSLDRELV-P 1285 Query: 762 KYELVIRA---ASPPLWNDVRVEILVTDVNDNAPV 793 Y + I A SP L +++ ++DVNDN P+ Sbjct: 1286 WYNITILATDRGSPQLSTMKFIKLDISDVNDNPPM 1320 Score = 340 bits (835), Expect = 4e-91 Identities = 267/905 (29%), Positives = 436/905 (48%), Gaps = 82/905 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++++ D ND++PVF Y A + E +G ++ ++A+D D G NA++ Y+I Sbjct: 1841 KLDISDVNDNAPVFTKSSYVAYIAENNLAGASIYRIQASDIDAGDNAKIIYSI------- 1893 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLT-RASLDREKVARYTVLVKATDQASPVSD 128 N E + F I +G + + + LDRE + +++ A+D PV Sbjct: 1894 YNTEPSP-------------FSISQHTGEIRSSQKPLDRETQKDHELILTASDGGDPVK- 1939 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 + TA I + + D NDN P F++ Y VS+ E+I + N + + ATD D G N+ I Sbjct: 1940 --TGTAIIRIIVTDANDNLPVFTKAVYKVSISENIPI--NSSVLHVNATDRDEGTNAQIT 1995 Query: 189 YAIIGGNTQ----MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 Y+ I + FSI+ ++G++ ++ LD+E R+Y + ++A DGG + +L Sbjct: 1996 YSFIKTSENDIHSPMFSINQINGEIKTLQKLDFELTRNYEMSVQATDGGGFVAKS---IL 2052 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG- 303 ++I DVNDN P F S + + EN G SI +VQA D D G N+++ Y++ + + Sbjct: 2053 LDISDVNDNPPVFLKSRYIAYLPENNLPGASIYKVQASDLDTGENSKVIYSVFNTNTEAF 2112 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 V +I+ +G +Y D E ++ + V A D G P S+ AT Sbjct: 2113 PVSSYFSINIETGVLYAQRSFDYEQHKEFAMHVQAKDNGYPSLSSNATLIIRIIDQNDNA 2172 Query: 364 XXFM-PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGR 420 + P + E P + TA D D ++ Y+++ TS +G Sbjct: 2173 PKILYPSTENSDSLIFEM--VPFAS-TAEDPDIGSNSVQTYKLSDNQYFTLNEKTSSDGS 2229 Query: 421 GL--ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTA 476 + + +PLD + + + L ++A+D G R+ TA++++ +TDAN+ PVF Y Sbjct: 2230 KFPELVLERPLDRETKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKV 2289 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 S+ E+ PI +TVL V+A+D D G NAQITYS S +V D + N + Sbjct: 2290 SISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSKYFSV---DLE---NGNLYELVLE 2343 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 + LDRE + + L +TA DGG P + T + + V D NDN PVF Q++Y +I E+ + Sbjct: 2344 RPLDREIKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISENTPI 2403 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREE---GSFVIDPASGVIRTN----------- 642 ++V +V A+D D G N +I Y F I+P SG + Sbjct: 2404 NSTVLRVNASDMDEGTNAQITYSFSRTSENSLHASMFSINPTSGEMNEKTSSDGSKFPEL 2463 Query: 643 ---KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699 + LDRE+ H+L A DGGTP ++ T ++ + + D ND+ PVF + ISEN Sbjct: 2464 VLERPLDRETKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISEN 2523 Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759 +PI +T+ + A D DEG NA + YS ++ + E+ T L++E+ Sbjct: 2524 TPINSTVLRVNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGEITTNNLLNFEA- 2582 Query: 760 RKKYELVIRAASPPLW----NDVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVGPFG 814 +K YE+ ++A + V I + D+NDNAP K F +++ + + VG Sbjct: 2583 KKDYEISVQAKDGGGFVAHSKVFPVIIEIQDINDNAP--KFFPVLYTVSISENTAVGSVV 2640 Query: 815 R-VPAYDAD--VTDKLQYRIL----SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867 V A D D + ++ Y S N ++ +N TTG + QLN + + V Sbjct: 2641 LCVNATDKDEGINAQITYSFSKTSESSLNKSMFSINPTTGEIKTEKQLNFEGTRNYELSV 2700 Query: 868 SVTDG 872 DG Sbjct: 2701 QAKDG 2705 Score = 335 bits (823), Expect = 1e-89 Identities = 269/902 (29%), Positives = 430/902 (47%), Gaps = 61/902 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND+ PVF +Y SV E GT A D DIG N+ Y EL D Sbjct: 3 VEIEDINDNYPVFPSSRYSISVPESRLPGTRFPLEGAVDADIGTNSITNY--ELSANDYF 60 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 E + +++I +S L+ + SLDREK++ + + + A D P +L Sbjct: 61 TLE-----------LPKFIYQI--KSIQLVLKKSLDREKISVHNLTLMAFDGGKP---KL 104 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY- 189 S + + +N+ D NDN P F++ Y S+ E + ++AK+ ATD DVG N Y Sbjct: 105 SGSTQLIINVEDVNDNPPVFNQSVYQCSITE--NAPKGTLVAKLFATDMDVGKNGETSYE 162 Query: 190 --AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 ++ FS+D +G+V + LDYE+ +Y ++I A D G + QLL+ + Sbjct: 163 FSKLVPERMLSLFSLDKYTGEVWVKGELDYEKSNTYEVLIDALDNGEHLLTGHCQLLVTV 222 Query: 248 RDVNDNAPRF-YTSLF----QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 DVNDNAP TSL +++ EN P G I V A D+D G N+ +TY++ + + Sbjct: 223 VDVNDNAPEMTVTSLSLPVPEDATHENNPPGSHIYTVSASDSDTGQNSFITYSL--RSGS 280 Query: 303 GNVDLPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 GN + + + + LDRE+ A+Y + ++ATD G P S TA Sbjct: 281 GNQTYSLNSKFSNYYSLVLKDNLDRESVAEYNVPISATDNGIPALSTTAYIYFSVDDIND 340 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRG---RFSITS 416 F Y +AE+ PG+ + ++A+D D ++ +L Y + G I+ Sbjct: 341 NPPLFTEELYFFSIAENILPGSLIFQVSASDKDSGKNAQLLYALLESYVEGMSVSHFISI 400 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPY 474 G + D+++ + +TV+ TDSG S + + ++D N+ P FE Y Sbjct: 401 NPDSGNVFSVDSFDYEKIPQKNITVTVTDSGTPPLSTQKTLYVEVSDLNDNPPTFEEKSY 460 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 + + E+ G +++ V ATD D N+ ++YSL A + F + TG I Sbjct: 461 SIYIMENNAPGVSLISVKATDLDSNENSFVSYSLLR-------ASDPKLFQVELHTGEIR 513 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 T LDRE S Y +T+ + D G P LS + +++ DVNDN P+FK+ Y A + E+ Sbjct: 514 TTSFLDRENTSQYNITILSTDRGSPKLSTVKHIRLNISDVNDNAPIFKKSTYVAYLSENN 573 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654 L G+S+ ++ A D D G N +I Y + + +F I+P SG I T + LD ESV +++ Sbjct: 574 LPGSSIYRINAYDPDTGDNAKIIYSI-AGTNIKSTFDINPTSGKITTKRDLDFESVQSYE 632 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 + A+DGG + V+ I+I D ND+ P L+ I E+S GT I I+ HD Sbjct: 633 IAIEAMDGGGFVAQTKVL--IEIIDENDNAPEISIASLSAPIPEDSMPGTVIALIKVHDQ 690 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---AS 771 D G N V I G S +R ++T LD E Y + I A S Sbjct: 691 DTGRNGEVDCQILGAAPFQIVSSSSRY----YRIITASFLDREKV-PWYNITILATDKGS 745 Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQY 829 P L + +++ ++DVNDN PV + ++ P R+ A+D D + K+ Y Sbjct: 746 PELSSTKSIKLDLSDVNDNPPVFSKPTYVAYLPENNLPGSSIYRIQAFDFDSGNNAKVVY 805 Query: 830 RILSGNNANLILLNETTG--SMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887 IL ++ + +N+ TG + + L+ K+ + ++ DG N ++ L I Sbjct: 806 SILM-SDPSPFSINQYTGEHKVVIMKPLDRENLKIHKLLLTAFDGGNPVRTGTALIRIAI 864 Query: 888 TE 889 T+ Sbjct: 865 TD 866 Score = 331 bits (814), Expect = 1e-88 Identities = 280/899 (31%), Positives = 430/899 (47%), Gaps = 79/899 (8%) Query: 2 SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 +V IH I ++D ND++P ++ E ++ GT + ++ DQD G+N EVE Sbjct: 1196 NVTLIIHI-IEIMDENDNAPEISIRSLSTPFPEDSAPGTLIALIEVHDQDSGENGEVECQ 1254 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121 I + P + R ++ SLDRE V Y + + ATD Sbjct: 1255 I-------IGPSPF------------QLLSSSSRYYKIVNTGSLDRELVPWYNITILATD 1295 Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181 + SP +LS+ I ++I D NDN P F + T+ + E + I I A+D D Sbjct: 1296 RGSP---QLSTMKFIKLDISDVNDNPPMFVKSTFVAYLPE--NNLPGASIYSIHASDPDY 1350 Query: 182 GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRS 238 G N+ I Y+I + F +DS +G + T LD E+ Y + I A D GSP S Sbjct: 1351 GNNAKIIYSISNIVGTVPFQLDSSTGRFYRIVTKSALDREKTALYNITIVATDKGSPQLS 1410 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 + + ++I DVNDN P F S + EN G SI R+QA D D G NA++ Y+++ Sbjct: 1411 SRKFIRLDISDVNDNPPVFMKSKDVAYLPENNLPGSSIYRIQASDLDTGDNAKVIYSISS 1470 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358 D N D PI+ + LDRETQ ++L++TA+DGG+P RS TA Sbjct: 1471 MD---NEDFPIS--SYFSKLVLEKPLDRETQTIHELILTASDGGNPVRSGTALIRIAVTD 1525 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQN 418 F Y+V ++E+ P + V+T+ ATD DE + +I FSI + Sbjct: 1526 SNDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGT--NAQIMYSFRSSFFSINIET 1583 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAP--VFENAPY 474 G++ + D++Q + + + V A D G S A + I ITD N+ P ++ ++ Sbjct: 1584 --GVLYAQRSFDYEQHKEFQIKVYAKDYGSPSLSCNASLTIRITDQNDNVPKILYPSSES 1641 Query: 475 TASVFEDAPI----GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 S FE P+ G + V A D+D G NA ++Y + F I+ T Sbjct: 1642 VDSSFEMVPVASEQGALITKVVAVDADSGHNAWLSYHV-------VQGSEPSLFSISQNT 1694 Query: 531 GAI-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589 G I T+ K LDRET + + L +TA DGG P S T + I+V D NDN PVF Q++Y + Sbjct: 1695 GEIRTSQKPLDRETQTIHELILTASDGGNPVRSGTALIRIAVTDANDNLPVFTQEVYKVS 1754 Query: 590 IM---EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV---IRTNK 643 I ED+ GT ++ + D D G NG E+D + G F + +S I T Sbjct: 1755 ITIIPEDSPSGTLIALIEVHDQDSGENG----EIDCQLLGTGPFQLLLSSTKYYRIITTG 1810 Query: 644 ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703 +LDRE V +++ A D G+P S+ ++ + I D+ND+ PVF YI+EN+ G Sbjct: 1811 SLDREKVPWYNITIQATDRGSPHLSNIKLIKLDISDVNDNAPVFTKSSYVAYIAENNLAG 1870 Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY 763 +I I+A D D G NA + YSI + S FS+ G ++ + LD E+ +K + Sbjct: 1871 ASIYRIQASDIDAGDNAKIIYSIYNTEPS-PFSISQHTGEIRS---SQKPLDRET-QKDH 1925 Query: 764 ELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPAY 819 EL++ A+ P + I+VTD NDN PV + + + P+ V A Sbjct: 1926 ELILTASDGGDPVKTGTAIIRIIVTDANDNLPVFTK-AVYKVSISENIPINSSVLHVNAT 1984 Query: 820 DAD--VTDKLQYRIL--SGNNAN--LILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 D D ++ Y + S N+ + + +N+ G + +L+ + + M V TDG Sbjct: 1985 DRDEGTNAQITYSFIKTSENDIHSPMFSINQINGEIKTLQKLDFELTRNYEMSVQATDG 2043 Score = 330 bits (810), Expect = 4e-88 Identities = 279/896 (31%), Positives = 423/896 (47%), Gaps = 76/896 (8%) Query: 20 SPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXX 79 SP FEM + ASV+ G+ + + A+D D G NA++ Y+I +N ED Sbjct: 1106 SPFFEMVPF-ASVQ-----GSLITKIHASDPDAGDNAKIIYSI-----SNINTED----- 1149 Query: 80 XXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTAT--IH 137 V F I+ +G L + S D E+ + + + A D SP LSS T IH Sbjct: 1150 ----FPVSPYFSINIETGVLYAQRSFDYEQHKEFQMKISAKDNGSP---PLSSNVTLIIH 1202 Query: 138 -VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNT 196 + I+D+NDN P+ S ++ + ED + +IA I+ D D G N + IIG + Sbjct: 1203 IIEIMDENDNAPEISIRSLSTPFPEDSA--PGTLIALIEVHDQDSGENGEVECQIIGPSP 1260 Query: 197 QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256 S S + +LD E V Y + I A D GSP S + ++I DVNDN P Sbjct: 1261 FQLLSSSSRYYKIVNTGSLDRELVPWYNITILATDRGSPQLSTMKFIKLDISDVNDNPPM 1320 Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316 F S F + EN G SI + A D D G NA++ Y+++ + G V P +D +G Sbjct: 1321 FVKSTFVAYLPENNLPGASIYSIHASDPDYGNNAKIIYSIS--NIVGTV--PFQLDSSTG 1376 Query: 317 WVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373 Y T LDRE A Y + + ATD G P S+ FM + Sbjct: 1377 RFYRIVTKSALDREKTALYNITIVATDKGSPQLSSRKFIRLDISDVNDNPPVFMKSKDVA 1436 Query: 374 ELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431 L E+ PG+ + + A+D D DN ++ Y I+ + F I+S + + + +PLD Sbjct: 1437 YLPENNLPGSSIYRIQASDLDTGDNAKVIYSISSMDNED-FPISSYFSK--LVLEKPLDR 1493 Query: 432 KQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 + + + L ++A+D G RS TA+++I +TD+N+ PVF Y S+ E+ PI +TVL Sbjct: 1494 ETQTIHELILTASDGGNPVRSGTALIRIAVTDSNDNLPVFTQEVYKVSISENIPINSTVL 1553 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 V+ATD D G NAQI YS S F IN +TG + + D E + + Sbjct: 1554 TVNATDRDEGTNAQIMYSFRSSF-----------FSINIETGVLYAQRSFDYEQHKEFQI 1602 Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEP--VFKQQLYTANIMEDALV----GTSVSQV 603 V A+D G PSLS + I + D NDN P ++ + E V G +++V Sbjct: 1603 KVYAKDYGSPSLSCNASLTIRITDQNDNVPKILYPSSESVDSSFEMVPVASEQGALITKV 1662 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN-KALDRESVATHDLKAVAIDG 662 A DAD G N + Y + + E F I +G IRT+ K LDRE+ H+L A DG Sbjct: 1663 VAVDADSGHNAWLSYHV-VQGSEPSLFSISQNTGEIRTSQKPLDRETQTIHELILTASDG 1721 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS---ENSPIGTTIGEIRAHDPDEGPN 719 G P +S T ++ I + D ND+ PVF + I+ E+SP GT I I HD D G N Sbjct: 1722 GNPVRSGTALIRIAVTDANDNLPVFTQEVYKVSITIIPEDSPSGTLIALIEVHDQDSGEN 1781 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776 + + G + F L + ++T LD E Y + I+A SP L N Sbjct: 1782 GEIDCQLLG---TGPFQL-LLSSTKYYRIITTGSLDREKV-PWYNITIQATDRGSPHLSN 1836 Query: 777 DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSG 834 +++ ++DVNDNAPV + ++ R+ A D D D K+ Y I + Sbjct: 1837 IKLIKLDISDVNDNAPVFTKSSYVAYIAENNLAGASIYRIQASDIDAGDNAKIIYSIYN- 1895 Query: 835 NNANLILLNETTGSMTLSPQ-LNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889 + +++ TG + S + L+ K + ++ +DG + +K + ++T+ Sbjct: 1896 TEPSPFSISQHTGEIRSSQKPLDRETQKDHELILTASDGGDPVKTGTAIIRIIVTD 1951 Score = 329 bits (809), Expect = 6e-88 Identities = 270/912 (29%), Positives = 426/912 (46%), Gaps = 83/912 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I V D ND+ PVF + Y+ S+ E +TVLT+ ATD+D G NA++ Y+ Sbjct: 1520 RIAVTDSNDNLPVFTQEVYKVSISENIPINSTVLTVNATDRDEGTNAQIMYSFR------ 1573 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 F I+ +G L + S D E+ + + V A D SP Sbjct: 1574 -----------------SSFFSINIETGVLYAQRSFDYEQHKEFQIKVYAKDYGSP---S 1613 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVT-----DNPVIAKIKATDADVGAN 184 LS A++ + I D NDN P+ + + SVD + +I K+ A DAD G N Sbjct: 1614 LSCNASLTIRITDQNDNVPKILYPS-SESVDSSFEMVPVASEQGALITKVVAVDADSGHN 1672 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDV-SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 + + Y ++ G+ FSI +G++ + K LD E + L++ A DGG+P RS T + Sbjct: 1673 AWLSYHVVQGSEPSLFSISQNTGEIRTSQKPLDRETQTIHELILTASDGGNPVRSGTALI 1732 Query: 244 LINIRDVNDNAPRFYTSLFQESVS---ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 I + D NDN P F +++ S++ E+ P G I ++ +D D G N E+ + Sbjct: 1733 RIAVTDANDNLPVFTQEVYKVSITIIPEDSPSGTLIALIEVHDQDSGENGEIDCQLLG-- 1790 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 TG L ++ + + T+G LDRE Y + + ATD G P S Sbjct: 1791 -TGPFQLLLS-STKYYRIITTGSLDREKVPWYNITIQATDRGSPHLSNIKLIKLDISDVN 1848 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTR-GRFSITSQNG 419 F Y +AE+ G + + A+D D + + NT FSI+ G Sbjct: 1849 DNAPVFTKSSYVAYIAENNLAGASIYRIQASDIDAGDNAKIIYSIYNTEPSPFSISQHTG 1908 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTAS 477 + + +PLD + ++ + L ++A+D G ++ TA+++I +TDAN+ PVF A Y S Sbjct: 1909 E-IRSSQKPLDRETQKDHELILTASDGGDPVKTGTAIIRIIVTDANDNLPVFTKAVYKVS 1967 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 + E+ PI ++VL V+ATD D G NAQITYS N+ H F IN G I T + Sbjct: 1968 ISENIPINSSVLHVNATDRDEGTNAQITYSFIKTSENDI---HSPMFSINQINGEIKTLQ 2024 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LD E Y ++V A DGG ++ + ++IS DVNDN PVF + Y A + E+ L G Sbjct: 2025 KLDFELTRNYEMSVQATDGG-GFVAKSILLDIS--DVNDNPPVFLKSRYIAYLPENNLPG 2081 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDRE----EGSFVIDPASGVIRTNKALDRESVATH 653 S+ +V A+D D G N ++ Y + + E F I+ +GV+ ++ D E Sbjct: 2082 ASIYKVQASDLDTGENSKVIYSVFNTNTEAFPVSSYFSINIETGVLYAQRSFDYEQHKEF 2141 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF------ESDCLTFYISENSPIGTTIG 707 + A D G P SS + I+I D ND+ P SD L F E P +T Sbjct: 2142 AMHVQAKDNGYPSLSSNATLIIRIIDQNDNAPKILYPSTENSDSLIF---EMVPFAST-- 2196 Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA---ELVTMVDLDYESPRKKYE 764 A DPD G N+V Y + D+ F+L + SD + ELV LD E+ + +E Sbjct: 2197 ---AEDPDIGSNSVQTYKL---SDNQYFTLNEKTSSDGSKFPELVLERPLDRET-KNIHE 2249 Query: 765 LVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPAYD 820 L++ A+ +P + ++VTD NDN PV ++ + + P+ RV A D Sbjct: 2250 LLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQ-EVYKVSISENTPINSTVLRVNASD 2308 Query: 821 ADVTDKLQYRILSGNNANLILLNETTGS---MTLSPQLNTNVPKLATMEVSVTDGVNEIK 877 D Q + ++ G+ + L L+ + + + ++ +DG ++ Sbjct: 2309 MDEGTNAQITYSFSRTSKYFSVDLENGNLYELVLERPLDREIKNIHELLLTASDGGTPVR 2368 Query: 878 AMMQLSVRLITE 889 L ++T+ Sbjct: 2369 TGTALIRVIVTD 2380 Score = 329 bits (809), Expect = 6e-88 Identities = 253/787 (32%), Positives = 393/787 (49%), Gaps = 50/787 (6%) Query: 89 VFRIDGRSGALLT-RASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 +F I +G + T + LDRE + +++ A+D +PV S TA I + + D NDN Sbjct: 1687 LFSISQNTGEIRTSQKPLDRETQTIHELILTASDGGNPVR---SGTALIRIAVTDANDNL 1743 Query: 148 PQFSEKTYTVSVDEDISVTDNP---VIAKIKATDADVGANSAIRYAIIG-GNTQMQFSID 203 P F+++ Y VS+ I D+P +IA I+ D D G N I ++G G Q+ S Sbjct: 1744 PVFTQEVYKVSIT--IIPEDSPSGTLIALIEVHDQDSGENGEIDCQLLGTGPFQLLLSST 1801 Query: 204 SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263 ++ +LD E+V Y + I+A D GSP SN + ++I DVNDNAP F S + Sbjct: 1802 KYYRIIT-TGSLDREKVPWYNITIQATDRGSPHLSNIKLIKLDISDVNDNAPVFTKSSYV 1860 Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323 ++EN G SI R+QA D D G NA++ Y++ + + + P +I +G + +S + Sbjct: 1861 AYIAENNLAGASIYRIQASDIDAGDNAKIIYSIYNTEPS-----PFSISQHTGEIRSSQK 1915 Query: 324 -LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382 LDRETQ ++L++TA+DGGDP ++ TA F Y+V ++E+ P Sbjct: 1916 PLDRETQKDHELILTASDGGDPVKTGTAIIRIIVTDANDNLPVFTKAVYKVSISENIPIN 1975 Query: 383 TPVVTLTATDADEDN--RLHYEI--TGGNT--RGRFSITSQNGRGLITVAQPLDFKQERR 436 + V+ + ATD DE ++ Y T N FSI NG I Q LDF+ R Sbjct: 1976 SSVLHVNATDRDEGTNAQITYSFIKTSENDIHSPMFSINQINGE--IKTLQKLDFELTRN 2033 Query: 437 YVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496 Y ++V ATD GG +++ ++I+D N+ PVF + Y A + E+ G ++ V A+D Sbjct: 2034 YEMSVQATDGGGFVAKSIL-LDISDVNDNPPVFLKSRYIAYLPENNLPGASIYKVQASDL 2092 Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556 D G N+++ YS+ + +N F IN +TG + + D E + + V A+D Sbjct: 2093 DTGENSKVIYSVFN--TNTEAFPVSSYFSINIETGVLYAQRSFDYEQHKEFAMHVQAKDN 2150 Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG-ATDADVGLNGR 615 G PSLS + I ++D NDN P LY + D+L+ V A D D+G N Sbjct: 2151 GYPSLSSNATLIIRIIDQNDNAPKI---LYPSTENSDSLIFEMVPFASTAEDPDIGSNSV 2207 Query: 616 IHYELDPKDR---EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672 Y+L E + + + LDRE+ H+L A DGGTP ++ T + Sbjct: 2208 QTYKLSDNQYFTLNEKTSSDGSKFPELVLERPLDRETKNIHELLLTASDGGTPVRTGTAL 2267 Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732 + + + D ND+ PVF + ISEN+PI +T+ + A D DEG NA + YS S Sbjct: 2268 IRVIVTDANDNTPVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSR--TS 2325 Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVND 789 FS++ G+ ELV LD E + +EL++ A+ +P + ++VTD ND Sbjct: 2326 KYFSVDLENGN-LYELVLERPLDREI-KNIHELLLTASDGGTPVRTGTALIRVIVTDAND 2383 Query: 790 NAPVMKDFQIIFNNYKDCFPV-GPFGRVPAYDADVTDKLQ----YRILSGN--NANLILL 842 N PV ++ + + P+ RV A D D Q + S N +A++ + Sbjct: 2384 NTPVFTQ-EVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSENSLHASMFSI 2442 Query: 843 NETTGSM 849 N T+G M Sbjct: 2443 NPTSGEM 2449 Score = 328 bits (807), Expect = 1e-87 Identities = 218/704 (30%), Positives = 352/704 (50%), Gaps = 30/704 (4%) Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDED-ISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194 + V I D NDNYP F Y++SV E + T P+ A DAD+G NS Y + Sbjct: 1 VDVEIEDINDNYPVFPSSRYSISVPESRLPGTRFPLEG---AVDADIGTNSITNYELSAN 57 Query: 195 N----TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + +F S + L K+LD E++ + L + A DGG P S +TQL+IN+ DV Sbjct: 58 DYFTLELPKFIYQIKSIQLVLKKSLDREKISVHNLTLMAFDGGKPKLSGSTQLIINVEDV 117 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F S++Q S++EN P G + ++ A D D G N E +Y + + L + Sbjct: 118 NDNPPVFNQSVYQCSITENAPKGTLVAKLFATDMDVGKNGETSYEFSKLVPERMLSL-FS 176 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 +D +G V+ G+LD E Y++L+ A D G+ + Sbjct: 177 LDKYTGEVWVKGELDYEKSNTYEVLIDALDNGEHLLTGHCQLLVTVVDVNDNAPEMTVTS 236 Query: 371 YEVELAED-----EPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQ-NGRGL 422 + + ED PPG+ + T++A+D+D +++ + Y + G+ +S+ S+ + Sbjct: 237 LSLPVPEDATHENNPPGSHIYTVSASDSDTGQNSFITYSLRSGSGNQTYSLNSKFSNYYS 296 Query: 423 ITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 + + LD + Y + +SATD+G S TA + ++ D N+ P+F Y S+ E Sbjct: 297 LVLKDNLDRESVAEYNVPISATDNGIPALSTTAYIYFSVDDINDNPPLFTEELYFFSIAE 356 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYS-LSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 + G+ + VSA+D D G NAQ+ Y+ L S + +V+H INP +G + + Sbjct: 357 NILPGSLIFQVSASDKDSGKNAQLLYALLESYVEGMSVSHF---ISINPDSGNVFSVDSF 413 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 D E + +TVT D G P LS + + V D+NDN P F+++ Y+ IME+ G S Sbjct: 414 DYEKIPQKNITVTVTDSGTPPLSTQKTLYVEVSDLNDNPPTFEEKSYSIYIMENNAPGVS 473 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 + V ATD D N + Y L + + F ++ +G IRT LDRE+ + +++ ++ Sbjct: 474 LISVKATDLDSNENSFVSYSL-LRASDPKLFQVELHTGEIRTTSFLDRENTSQYNITILS 532 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 D G+P S+ + + I D+ND+ P+F+ Y+SEN+ G++I I A+DPD G N Sbjct: 533 TDRGSPKLSTVKHIRLNISDVNDNAPIFKKSTYVAYLSENNLPGSSIYRINAYDPDTGDN 592 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDV 778 A + YSI G + ++F + G ++ T DLD+ES + YE+ I A Sbjct: 593 AKIIYSIAGTNIKSTFDINPTSG----KITTKRDLDFESV-QSYEIAIEAMDGGGFVAQT 647 Query: 779 RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD 822 +V I + D NDNAP + + +D P + +D D Sbjct: 648 KVLIEIIDENDNAPEISIASLSAPIPEDSMPGTVIALIKVHDQD 691 Score = 278 bits (681), Expect = 2e-72 Identities = 188/567 (33%), Positives = 283/567 (49%), Gaps = 40/567 (7%) Query: 99 LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158 L+ LDRE + +L+ A+D +PV + TA I V + D NDN P F+++ Y VS Sbjct: 2234 LVLERPLDRETKNIHELLLTASDGGTPVR---TGTALIRVIVTDANDNTPVFTQEVYKVS 2290 Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG---DVSLVKTL 215 + E+ + N + ++ A+D D G N+ I Y+ T FS+D +G ++ L + L Sbjct: 2291 ISENTPI--NSTVLRVNASDMDEGTNAQITYSF--SRTSKYFSVDLENGNLYELVLERPL 2346 Query: 216 DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275 D E + L++ A DGG+P R+ T + + + D NDN P F +++ S+SEN PI + Sbjct: 2347 DREIKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISENTPINST 2406 Query: 276 IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY--TSGQ---------- 323 ++RV A D DEG NA++TY+ + +I+P SG + TS Sbjct: 2407 VLRVNASDMDEGTNAQITYSFSRTSENSLHASMFSINPTSGEMNEKTSSDGSKFPELVLE 2466 Query: 324 --LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381 LDRET+ ++LL+TA+DGG P R+ TA F Y+V ++E+ P Sbjct: 2467 RPLDRETKNIHELLLTASDGGTPVRTGTALIRVIVTDANDNTPVFTQEVYKVSISENTPI 2526 Query: 382 GTPVVTLTATDADEDNRLHYEITGGNTR------GRFSITSQNGRGLITVAQPLDFKQER 435 + V+ + A+D DE + T FSI +G IT L+F+ ++ Sbjct: 2527 NSTVLRVNASDMDEGTNAQITYSFSRTSVNSLHASMFSINPTSGE--ITTNNLLNFEAKK 2584 Query: 436 RYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492 Y ++V A D GG S V I I D N+ AP F YT S+ E+ +G+ VL V+ Sbjct: 2585 DYEISVQAKDGGGFVAHSKVFPVIIEIQDINDNAPKFFPVLYTVSISENTAVGSVVLCVN 2644 Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552 ATD D GINAQITYS S + + F INP TG I T K L+ E Y L+V Sbjct: 2645 ATDKDEGINAQITYSFSKTSESSL---NKSMFSINPTTGEIKTEKQLNFEGTRNYELSVQ 2701 Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612 A+DGG + V I + D NDN P + + ED+ G+ ++ + D D G Sbjct: 2702 AKDGG--GFVTHSKVLIEITDENDNAPEISIASLSTPVPEDSAPGSVIALIEVHDQDSGS 2759 Query: 613 NGRIHYELDPKDREEGSFVIDPASGVI 639 N +I Y + + F I+ +GV+ Sbjct: 2760 NAKITYSISETNTMSPYFSINIETGVL 2786 Score = 193 bits (471), Expect = 5e-47 Identities = 121/419 (28%), Positives = 208/419 (49%), Gaps = 18/419 (4%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ V D ND++PVF + Y+ S+ E +TVL + A+D D G NA++ Y+ + ++ Sbjct: 2375 RVIVTDANDNTPVFTQEVYKVSISENTPINSTVLRVNASDMDEGTNAQITYSFSRTSENS 2434 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 L+ + + + DG + L+ LDRE + +L+ A+D +PV Sbjct: 2435 LHA--SMFSINPTSGEMNEKTSSDGSKFPELVLERPLDRETKNIHELLLTASDGGTPVR- 2491 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 + TA I V + D NDN P F+++ Y VS+ E+ + N + ++ A+D D G N+ I Sbjct: 2492 --TGTALIRVIVTDANDNTPVFTQEVYKVSISENTPI--NSTVLRVNASDMDEGTNAQIT 2547 Query: 189 YAI----IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS-PSRSNTTQL 243 Y+ + FSI+ SG+++ L++E + Y + ++A+DGG + S + Sbjct: 2548 YSFSRTSVNSLHASMFSINPTSGEITTNNLLNFEAKKDYEISVQAKDGGGFVAHSKVFPV 2607 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 +I I+D+NDNAP+F+ L+ S+SEN +G ++ V A D DEG+NA++TY+ + + Sbjct: 2608 IIEIQDINDNAPKFFPVLYTVSISENTAVGSVVLCVNATDKDEGINAQITYSFSKTSESS 2667 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 +I+P +G + T QL+ E Y+L V A DGG + Sbjct: 2668 LNKSMFSINPTTGEIKTEKQLNFEGTRNYELSVQAKDGGGFVTHSKVLIEITDENDNAPE 2727 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRG-RFSITSQNG 419 + ED PG+ + + D D + ++ Y I+ NT FSI + G Sbjct: 2728 ISI--ASLSTPVPEDSAPGSVIALIEVHDQDSGSNAKITYSISETNTMSPYFSINIETG 2784 Score = 178 bits (433), Expect = 2e-42 Identities = 132/416 (31%), Positives = 205/416 (49%), Gaps = 27/416 (6%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 V + I D N+ PVF ++ Y+ SV E GT + A D+D+G N+ Y LS+ N Sbjct: 1 VDVEIEDINDNYPVFPSSRYSISVPESRLPGTRFPLEGAVDADIGTNSITNYELSA---N 57 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 + +F+ ++ + K LDRE +S + LT+ A DGG P LS +T + I+V DV Sbjct: 58 DYFTLELPKFIYQIKSIQLVLKKSLDREKISVHNLTLMAFDGGKPKLSGSTQLIINVEDV 117 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP--KDREEGSFVI 632 NDN PVF Q +Y +I E+A GT V+++ ATD DVG NG YE +R F + Sbjct: 118 NDNPPVFNQSVYQCSITENAPKGTLVAKLFATDMDVGKNGETSYEFSKLVPERMLSLFSL 177 Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692 D +G + LD E T+++ A+D G + + + + D+ND+ P L Sbjct: 178 DKYTGEVWVKGELDYEKSNTYEVLIDALDNGEHLLTGHCQLLVTVVDVNDNAPEMTVTSL 237 Query: 693 TFYI-----SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747 + + EN+P G+ I + A D D G N+ + YS++ G + ++SL ++ S+ Sbjct: 238 SLPVPEDATHENNPPGSHIYTVSASDSDTGQNSFITYSLRSGSGNQTYSLNSK-FSNYYS 296 Query: 748 LVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY 804 LV +LD ES +Y + I A P L + V D+NDN P+ + F+ Sbjct: 297 LVLKDNLDRESV-AEYNVPISATDNGIPALSTTAYIYFSVDDINDNPPLFTEELYFFSIA 355 Query: 805 KDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLI--LLNETTGSMTLSPQLNTN 858 ++ P +V A D D SG NA L+ LL M++S ++ N Sbjct: 356 ENILPGSLIFQVSASDKD----------SGKNAQLLYALLESYVEGMSVSHFISIN 401 >UniRef50_Q17NI8 Cluster: Cadherin; n=3; cellular organisms|Rep: Cadherin - Aedes aegypti (Yellowfever mosquito) Length = 3131 Score = 372 bits (914), Expect = e-100 Identities = 285/891 (31%), Positives = 417/891 (46%), Gaps = 81/891 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+V+D P+F+ +Y V+E T V T+ AT + G + Y I D Sbjct: 442 ISVIDATQRPPIFDKPRYTYYVKEDVKKNTVVGTVSATSSNSGSRGSIRYFIYSGDPD-- 499 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F ID SG + ++LD E + + ++AT P Sbjct: 500 -----------------GYFAIDPVSGNIRVASTLDHETKPQVLLNIQATSGDPPAYGHT 542 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 ++++I D NDN P+F T +SV E++ + +P+ A A D D G + I Y Sbjct: 543 Q----VNIDIEDVNDNPPEFESSTVRISVPENVEI-GSPLYAA-NAHDKDSGMSGVITYR 596 Query: 191 II--GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 + G T FSIDS SG +SL + LDYE V+ + L++ A D G PS S +L+ ++ Sbjct: 597 LSNNGPATGNLFSIDSRSGHLSLARPLDYETVQRHTLIVTASDSGIPSLSTNLTILVEVQ 656 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY---TG-- 303 DVNDNAP F S + VSE+ P I++V A DAD G NA LTY + D TG Sbjct: 657 DVNDNAPVFERSEYAIKVSESTPSNSQIMQVTAVDADTGNNARLTYRILGDDQRTRTGKS 716 Query: 304 -------NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 N I P SGW+Y +LDRE Q +Y + V +D G P +AT Sbjct: 717 SSKASEANTPEIFGIFPNSGWIYLRTKLDREDQERYNITVIVSDNGVPTLTATTHVIVSV 776 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSI 414 F YE ++ E+ G+ + +TATDAD + + Y + NT F I Sbjct: 777 LDANDNNPIFAKQLYEFQIEENMRRGSVIGLITATDADAGINAVVRYSLIPSNT--SFQI 834 Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAP-VFEN 471 +G IT LD + + Y L V A D G RS ++I I D N+ +P + + Sbjct: 835 NPISGE--ITTRDRLDRETKSIYDLVVEARDQGTPYRSSRVSIKIKILDVNDNSPEIVDP 892 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 SV E+ PIGT V+ V A D D G+NA ITYS+ ++ H F I+P TG Sbjct: 893 QEDVVSVREEQPIGTEVVRVRAIDRDYGVNASITYSILK--GRDSDGH--GMFTIDPITG 948 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 I T LD E + Y L V A D G P + I V+D+NDN P F + Sbjct: 949 LIRTKASLDHEEKTIYRLAVAATDNGKPPRQTVRLLRIEVLDLNDNRPTFTSSSLVFRLR 1008 Query: 592 EDALVGTSVSQVGATDAD-----VGLNGRIH--YELDP--KDREEGSFVIDPASGVIRTN 642 ED VG + + + + + +H Y L P D EG+F ID SG + Sbjct: 1009 EDVGVGHVIGSISGNEQSDLENLITSSNDLHITYTLTPLTNDIAEGAFDIDRNSGKLVVA 1068 Query: 643 KALDRESVATHDLKAVAID--GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700 ++LDRE + + ++ A+D PQSS V V I+I D+ND+PP + SD + YISE++ Sbjct: 1069 RSLDREQQSEYRMEIRALDTSASNNPQSSAVTVKIEIADVNDNPPKWPSDPMNVYISEDA 1128 Query: 701 PIGTTIGEIRAHDPDEGPNAVVHYSIK--GGDDSNSFSLETRQGSDKAELVTMVDLDYES 758 +G+ + A D D G NA + Y+I FS+++ GS L + LDYE Sbjct: 1129 AVGSVVFNFTATDNDSGTNAEIKYNISKPATAQKEFFSIDSLTGS----LTLLAPLDYEE 1184 Query: 759 PRKKYELVIRA------ASPPLWNDVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFPV 810 K++ L+++A + + I+VTDVNDN+P V+ Q D V Sbjct: 1185 -TKEFLLIVQATDQSSNVTERMTTSATARIMVTDVNDNSPKFVVPQAQDTTVYVSDSMEV 1243 Query: 811 GPF-GRVPAYDADVTD--KLQYRILSGNNANLILLNETTGSMTLSPQLNTN 858 V A D D + ++ Y+I+SGN ++ TG + L+ ++N Sbjct: 1244 NHIVSHVVAIDRDSGENGRVVYKIVSGNEDERFAIDPDTGFVKLAKPFSSN 1294 Score = 357 bits (878), Expect = 2e-96 Identities = 282/919 (30%), Positives = 439/919 (47%), Gaps = 85/919 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSG----TTVLTLKATDQDIGKNAEVEYTIELV 65 +I + D ND+ P F ++Y S+RE + T V+ + ATD D G + Y I V Sbjct: 330 KIQLTDVNDNRPTFYPREYNVSLRESMPTNSLLSTPVVVIVATDSDSGSFGTISYRI--V 387 Query: 66 TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVL-VKATDQA 123 + +FR+D +G + + R ++ + Y L + A+D Sbjct: 388 AGNEAG-----------------IFRMDRLTGEIFVARPNMLSSRSQPYHRLNISASDGG 430 Query: 124 SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183 R + A + +++ID P F + YT V ED+ N V+ + AT ++ G+ Sbjct: 431 GL---RSTHDAEVFISVIDATQRPPIFDKPRYTYYVKEDVK--KNTVVGTVSATSSNSGS 485 Query: 184 NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 +IRY I G+ F+ID +SG++ + TLD+E L I+A G P+ +T Q+ Sbjct: 486 RGSIRYFIYSGDPDGYFAIDPVSGNIRVASTLDHETKPQVLLNIQATSGDPPAYGHT-QV 544 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD-YT 302 I+I DVNDN P F +S + SV ENV IG + A+D D G++ +TY +++ T Sbjct: 545 NIDIEDVNDNPPEFESSTVRISVPENVEIGSPLYAANAHDKDSGMSGVITYRLSNNGPAT 604 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 GN+ +ID RSG + + LD ET ++ L+VTA+D G P S T Sbjct: 605 GNL---FSIDSRSGHLSLARPLDYETVQRHTLIVTASDSGIPSLSTNLTILVEVQDVNDN 661 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGR 420 F +Y ++++E P + ++ +TA DAD N RL Y I G + R R +S Sbjct: 662 APVFERSEYAIKVSESTPSNSQIMQVTAVDADTGNNARLTYRILGDDQRTRTGKSSSKAS 721 Query: 421 --------------GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANN 464 G I + LD + + RY +TV +D+G + TA V +++ DAN+ Sbjct: 722 EANTPEIFGIFPNSGWIYLRTKLDREDQERYNITVIVSDNGVPTLTATTHVIVSVLDAND 781 Query: 465 YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524 P+F Y + E+ G+ + +++ATD+D GINA + YSL SN + F Sbjct: 782 NNPIFAKQLYEFQIEENMRRGSVIGLITATDADAGINAVVRYSLIP--SNTS-------F 832 Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP-VFKQ 583 INP +G ITT LDRET S Y L V ARD G P S ++I ++DVNDN P + Sbjct: 833 QINPISGEITTRDRLDRETKSIYDLVVEARDQGTPYRSSRVSIKIKILDVNDNSPEIVDP 892 Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE-LDPKDRE-EGSFVIDPASGVIRT 641 Q ++ E+ +GT V +V A D D G+N I Y L +D + G F IDP +G+IRT Sbjct: 893 QEDVVSVREEQPIGTEVVRVRAIDRDYGVNASITYSILKGRDSDGHGMFTIDPITGLIRT 952 Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701 +LD E + L A D G PP+ + ++ I++ D+ND+ P F S L F + E+ Sbjct: 953 KASLDHEEKTIYRLAVAATDNGKPPRQTVRLLRIEVLDLNDNRPTFTSSSLVFRLREDVG 1012 Query: 702 IGTTIGEIRAHDPDEGPNAV-------VHYSIKG-GDDSNSFSLETRQGSDKAELVTMVD 753 +G IG I ++ + N + + Y++ +D + + + S K LV Sbjct: 1013 VGHVIGSISGNEQSDLENLITSSNDLHITYTLTPLTNDIAEGAFDIDRNSGK--LVVARS 1070 Query: 754 LDYESPRKKYELVIRA-----ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCF 808 LD E + +Y + IRA ++ P + V V+I + DVNDN P + +D Sbjct: 1071 LDREQ-QSEYRMEIRALDTSASNNPQSSAVTVKIEIADVNDNPPKWPSDPMNVYISEDAA 1129 Query: 809 PVGPFGRVPAYDAD--VTDKLQYRILSGNNAN--LILLNETTGSMTLSPQLNTNVPKLAT 864 A D D +++Y I A ++ TGS+TL L+ K Sbjct: 1130 VGSVVFNFTATDNDSGTNAEIKYNISKPATAQKEFFSIDSLTGSLTLLAPLDYEETKEFL 1189 Query: 865 MEVSVTDGVNEIKAMMQLS 883 + V TD + + M S Sbjct: 1190 LIVQATDQSSNVTERMTTS 1208 Score = 353 bits (867), Expect = 5e-95 Identities = 269/906 (29%), Positives = 420/906 (46%), Gaps = 66/906 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D ND++PVFE +Y V E S + ++ + A D D G NA + Y I D Sbjct: 653 VEVQDVNDNAPVFERSEYAIKVSESTPSNSQIMQVTAVDADTGNNARLTYRI---LGDDQ 709 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 ++F I SG + R LDRE RY + V +D P L Sbjct: 710 RTRTGKSSSKASEANTPEIFGIFPNSGWIYLRTKLDREDQERYNITVIVSDNGVPT---L 766 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 ++T + V+++D NDN P F+++ Y ++E ++ VI I ATDAD G N+ +RY+ Sbjct: 767 TATTHVIVSVLDANDNNPIFAKQLYEFQIEE--NMRRGSVIGLITATDADAGINAVVRYS 824 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 +I NT F I+ +SG+++ LD E Y LV+ A+D G+P RS+ + I I DV Sbjct: 825 LIPSNT--SFQINPISGEITTRDRLDRETKSIYDLVVEARDQGTPYRSSRVSIKIKILDV 882 Query: 251 NDNAPRFYTSLFQ-ESVSENVPIGYSIVRVQAYDADEGVNAELTYT-MTDKDYTGNVDLP 308 NDN+P SV E PIG +VRV+A D D GVNA +TY+ + +D G+ Sbjct: 883 NDNSPEIVDPQEDVVSVREEQPIGTEVVRVRAIDRDYGVNASITYSILKGRDSDGHG--M 940 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 TIDP +G + T LD E + Y+L V ATD G PPR F Sbjct: 941 FTIDPITGLIRTKASLDHEEKTIYRLAVAATDNGKPPRQTVRLLRIEVLDLNDNRPTFTS 1000 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADE-------DNRLHY-----EITGGNTRGRFSITS 416 L ED G + +++ + + N LH +T G F I Sbjct: 1001 SSLVFRLREDVGVGHVIGSISGNEQSDLENLITSSNDLHITYTLTPLTNDIAEGAFDIDR 1060 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGG----RSDTAMVQINITDANNYAPVFENA 472 +G+ + VA+ LD +Q+ Y + + A D+ +S V+I I D N+ P + + Sbjct: 1061 NSGK--LVVARSLDREQQSEYRMEIRALDTSASNNPQSSAVTVKIEIADVNDNPPKWPSD 1118 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 P + EDA +G+ V +ATD+D G NA+I Y+ IS A A + F I+ TG+ Sbjct: 1119 PMNVYISEDAAVGSVVFNFTATDNDSGTNAEIKYN----ISKPATA-QKEFFSIDSLTGS 1173 Query: 533 ITTNKLLDRETMSGYLLTVTARDGG---VPSLSDTTDVEISVVDVNDNEPVF---KQQLY 586 +T LD E +LL V A D ++ + I V DVNDN P F + Q Sbjct: 1174 LTLLAPLDYEETKEFLLIVQATDQSSNVTERMTTSATARIMVTDVNDNSPKFVVPQAQDT 1233 Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646 T + + V VS V A D D G NGR+ Y++ E+ F IDP +G ++ K Sbjct: 1234 TVYVSDSMEVNHIVSHVVAIDRDSGENGRVVYKI-VSGNEDERFAIDPDTGFVKLAKPFS 1292 Query: 647 RESVA---------THDLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696 +A ++L A D GTP + + + + + I++ +++PP F I Sbjct: 1293 SNFIADNSKNSITGRYNLVITATDQGTPRSKEAKITIQVVIQNTSNNPPRFLESVYHINI 1352 Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSI-KG-GDD----SNSFSLETRQGSDKAELVT 750 +EN P G+ + + A ++ NA + Y I KG GDD + + T +G+ E Sbjct: 1353 TENVPTGSFVVRVSAKSYNDNGNANLTYEIPKGVGDDHFVVDSVRGIVTTRGTFDRESKD 1412 Query: 751 MVDLD-YESPRKKYELVIRAASPPL--WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC 807 M + Y + + +++ S + ++ + + +TDVND+AP + Sbjct: 1413 MYTVPIYVTEQNRFKSAASGTSKDMSQFDVATLVVRITDVNDHAPEFLPGSCYPLAVPEN 1472 Query: 808 FPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATM 865 + V A DAD + ++ Y I GN N ++ TG++T P L+ + + Sbjct: 1473 SELSVIHTVVASDADEGLNGEITYSISGGNIGNKFSIDMNTGALTARP-LDREIHARYVL 1531 Query: 866 EVSVTD 871 +++ D Sbjct: 1532 QITAQD 1537 Score = 343 bits (842), Expect = 6e-92 Identities = 250/778 (32%), Positives = 375/778 (48%), Gaps = 53/778 (6%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F I +G + A LD E Y + ATD+ LS+TA + + + D NDN P Sbjct: 288 FEIRSSTGEVCIAAELDYETRNSYEFPIIATDRGG-----LSTTAMVKIQLTDVNDNRPT 342 Query: 150 FSEKTYTVSVDEDI---SVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206 F + Y VS+ E + S+ PV+ I ATD+D G+ I Y I+ GN F +D L+ Sbjct: 343 FYPREYNVSLRESMPTNSLLSTPVVV-IVATDSDSGSFGTISYRIVAGNEAGIFRMDRLT 401 Query: 207 GDVSLVK--TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF----YTS 260 G++ + + L +RL I A DGG ++ ++ I++ D P F YT Sbjct: 402 GEIFVARPNMLSSRSQPYHRLNISASDGGGLRSTHDAEVFISVIDATQRPPIFDKPRYTY 461 Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT 320 +E V +N +G V A ++ G + Y + Y+G+ D IDP SG + Sbjct: 462 YVKEDVKKNTVVG----TVSATSSNSGSRGSIRYFI----YSGDPDGYFAIDPVSGNIRV 513 Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380 + LD ET+ + L + AT GDPP F + + E+ Sbjct: 514 ASTLDHETKPQVLLNIQAT-SGDPPAYGHTQVNIDIEDVNDNPPEFESSTVRISVPENVE 572 Query: 381 PGTPVVTLTATDADE--DNRLHYEIT--GGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436 G+P+ A D D + Y ++ G T FSI S++G +++A+PLD++ +R Sbjct: 573 IGSPLYAANAHDKDSGMSGVITYRLSNNGPATGNLFSIDSRSGH--LSLARPLDYETVQR 630 Query: 437 YVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494 + L V+A+DSG S + + + D N+ APVFE + Y V E P + ++ V+A Sbjct: 631 HTLIVTASDSGIPSLSTNLTILVEVQDVNDNAPVFERSEYAIKVSESTPSNSQIMQVTAV 690 Query: 495 DSDVGINAQITYSL---------SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 D+D G NA++TY + S + A+ + F I P +G I LDRE Sbjct: 691 DADTGNNARLTYRILGDDQRTRTGKSSSKASEANTPEIFGIFPNSGWIYLRTKLDREDQE 750 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 Y +TV D GVP+L+ TT V +SV+D NDN P+F +QLY I E+ G+ + + A Sbjct: 751 RYNITVIVSDNGVPTLTATTHVIVSVLDANDNNPIFAKQLYEFQIEENMRRGSVIGLITA 810 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 TDAD G+N + Y L P + SF I+P SG I T LDRE+ + +DL A D GTP Sbjct: 811 TDADAGINAVVRYSLIPSNT---SFQINPISGEITTRDRLDRETKSIYDLVVEARDQGTP 867 Query: 666 PQSSTVIVHIKIEDIND-SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 +SS V + IKI D+ND SP + + + E PIGT + +RA D D G NA + Y Sbjct: 868 YRSSRVSIKIKILDVNDNSPEIVDPQEDVVSVREEQPIGTEVVRVRAIDRDYGVNASITY 927 Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVE 781 SI G DS+ + T + T LD+E + Y L + A PP + Sbjct: 928 SILKGRDSDGHGMFTID-PITGLIRTKASLDHEE-KTIYRLAVAATDNGKPPRQTVRLLR 985 Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANL 839 I V D+NDN P ++F +D VG + + + L+ I S N+ ++ Sbjct: 986 IEVLDLNDNRPTFTSSSLVFRLRED---VGVGHVIGSISGNEQSDLENLITSSNDLHI 1040 Score = 327 bits (804), Expect = 2e-87 Identities = 274/906 (30%), Positives = 430/906 (47%), Gaps = 80/906 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I VLD ND+ P F +RE G + ++ +Q +N + + +L T Sbjct: 985 RIEVLDLNDNRPTFTSSSLVFRLREDVGVGHVIGSISGNEQSDLENL-ITSSNDLHITYT 1043 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L P + F ID SG L+ SLDRE+ + Y + ++A D S ++ Sbjct: 1044 LTP--------LTNDIAEGAFDIDRNSGKLVVARSLDREQQSEYRMEIRALD-TSASNNP 1094 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 SS T+ + I D NDN P++ V + ED +V V+ ATD D G N+ I+Y Sbjct: 1095 QSSAVTVKIEIADVNDNPPKWPSDPMNVYISEDAAV--GSVVFNFTATDNDSGTNAEIKY 1152 Query: 190 AIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS--PSRSNTTQLL- 244 I T + FSIDSL+G ++L+ LDYE+ + + L+++A D S R T+ Sbjct: 1153 NISKPATAQKEFFSIDSLTGSLTLLAPLDYEETKEFLLIVQATDQSSNVTERMTTSATAR 1212 Query: 245 INIRDVNDNAPRFYTSLFQES---VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 I + DVNDN+P+F Q++ VS+++ + + + V A D D G N + Y K Sbjct: 1213 IMVTDVNDNSPKFVVPQAQDTTVYVSDSMEVNHIVSHVVAIDRDSGENGRVVY----KIV 1268 Query: 302 TGNVDLPITIDPRSGWV---------YTSGQLDRETQAKYQLLVTATDGGDP-PRSATAT 351 +GN D IDP +G+V + + +Y L++TATD G P + A T Sbjct: 1269 SGNEDERFAIDPDTGFVKLAKPFSSNFIADNSKNSITGRYNLVITATDQGTPRSKEAKIT 1328 Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTR 409 F+ Y + + E+ P G+ VV ++A +++ L YEI G Sbjct: 1329 IQVVIQNTSNNPPRFLESVYHINITENVPTGSFVVRVSAKSYNDNGNANLTYEIPKGVGD 1388 Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD-------SGGRS------DTAMVQ 456 F + S RG++T D + + Y + + T+ + G S D A + Sbjct: 1389 DHFVVDSV--RGIVTTRGTFDRESKDMYTVPIYVTEQNRFKSAASGTSKDMSQFDVATLV 1446 Query: 457 INITDANNYAPVF-ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515 + ITD N++AP F + Y +V E++ + + + V A+D+D G+N +ITYS+S Sbjct: 1447 VRITDVNDHAPEFLPGSCYPLAVPENSEL-SVIHTVVASDADEGLNGEITYSISG----- 1500 Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDV 574 + +F I+ TGA+T + LDRE + Y+L +TA+D G P S ++ + V D Sbjct: 1501 --GNIGNKFSIDMNTGALTA-RPLDREIHARYVLQITAQDRGSPTSHQGHCNITVRVEDE 1557 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634 NDN+P F+ Q Y A I EDA +GT+V V A DAD+G+N RI Y L + E F ID Sbjct: 1558 NDNDPKFELQKYIATIDEDAPIGTTVLTVKAVDADIGINARIVYSL--ANVTEWLFDIDS 1615 Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGT-PPQSSTVIVHIKIEDINDSPPVFESDCLT 693 SGVI T DRE + ++ VA DGG +S +V V + I D+ND+ PVF+ Sbjct: 1616 KSGVITTAGHFDRERQSIYNFMVVATDGGRYNARSQSVQVQVIIADVNDNKPVFDKYPFK 1675 Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753 I G T+ I A D D+G N + YS+ ++ F + G+ L Sbjct: 1676 EQIGALVQPGQTLLHISATDVDQGSNGEIVYSLNDNPNNAKFRINPNTGA----LSATQS 1731 Query: 754 LDYESPRKKY-ELVIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYK-DCFPV 810 L E+ R + E+ R +PP +E+ V D+ P +K FQ N+YK + Sbjct: 1732 LASENGRLLHIEVTARDKGNPPQVATGLIELRVGDLQQELPALK-FQ--NNSYKVNLVEN 1788 Query: 811 GPFGRVPAY-DADVTD----KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATM 865 P G+ + +A +D K+ Y SGN ++ TG + + N + + + + Sbjct: 1789 TPIGQTVLHLNAVRSDGRRQKIIYSFGSGNEDGTFSIDAVTGEVKIRNSHNLDYERFSRL 1848 Query: 866 EVSVTD 871 D Sbjct: 1849 NTEGID 1854 Score = 317 bits (779), Expect = 2e-84 Identities = 246/809 (30%), Positives = 387/809 (47%), Gaps = 71/809 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 Q+ + + +++ P F Y ++ E +G+ V+ + A + NA + Y I D Sbjct: 1330 QVVIQNTSNNPPRFLESVYHINITENVPTGSFVVRVSAKSYNDNGNANLTYEIPKGVGD- 1388 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ------A 123 D F +D G + TR + DRE YTV + T+Q A Sbjct: 1389 ------------------DHFVVDSVRGIVTTRGTFDRESKDMYTVPIYVTEQNRFKSAA 1430 Query: 124 SPVSDRLSS--TATIHVNIIDDNDNYPQFSEKT-YTVSVDEDISVTDNPVIAKIKATDAD 180 S S +S AT+ V I D ND+ P+F + Y ++V E+ ++ VI + A+DAD Sbjct: 1431 SGTSKDMSQFDVATLVVRITDVNDHAPEFLPGSCYPLAVPENSELS---VIHTVVASDAD 1487 Query: 181 VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP-SRSN 239 G N I Y+I GGN +FSID +G ++ + LD E Y L I AQD GSP S Sbjct: 1488 EGLNGEITYSISGGNIGNKFSIDMNTGALT-ARPLDREIHARYVLQITAQDRGSPTSHQG 1546 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 + + + D NDN P+F + ++ E+ PIG +++ V+A DAD G+NA + Y++ + Sbjct: 1547 HCNITVRVEDENDNDPKFELQKYIATIDEDAPIGTTVLTVKAVDADIGINARIVYSLANV 1606 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD-PPRSATATXXXXXXX 358 + ID +SG + T+G DRE Q+ Y +V ATDGG RS + Sbjct: 1607 -----TEWLFDIDSKSGVITTAGHFDRERQSIYNFMVVATDGGRYNARSQSVQVQVIIAD 1661 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITS 416 F ++ ++ PG ++ ++ATD D+ + + Y + +F I Sbjct: 1662 VNDNKPVFDKYPFKEQIGALVQPGQTLLHISATDVDQGSNGEIVYSLNDNPNNAKFRINP 1721 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSD--TAMVQINITDANNYAPV--FENA 472 G ++ Q L + R + V+A D G T ++++ + D P F+N Sbjct: 1722 NTGA--LSATQSLASENGRLLHIEVTARDKGNPPQVATGLIELRVGDLQQELPALKFQNN 1779 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 Y ++ E+ PIG TVL ++A SD G +I YS S NE D F I+ TG Sbjct: 1780 SYKVNLVENTPIGQTVLHLNAVRSD-GRRQKIIYSFGS--GNE-----DGTFSIDAVTGE 1831 Query: 533 --ITTNKLLDRETMS-----GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585 I + LD E S G L AR G P L +++ + D NDN P F QQ Sbjct: 1832 VKIRNSHNLDYERFSRLNTEGIDLVAVARTDGSPLLYGYCSIKVVLQDENDNAPRFTQQQ 1891 Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA-SGVIRTNKA 644 Y+A++ E G V +V A D D G N I Y + + +F+I+PA SG+++TN Sbjct: 1892 YSASVWEGNNKGEFVIKVNAFDTDQGSNAHILYHI-VDGNHDNAFIIEPAFSGIVKTNIV 1950 Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 LDRE + LK +A D G P + T +++ + D+ND+ P F + + +SE + +GT Sbjct: 1951 LDREIRDKYKLKVIATDEGVPQMTGTATINVNVVDVNDNQPTFPPNSV-ISVSEATTVGT 2009 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNS-FSLETRQGSDKAELVTMVDLDYESPRKKY 763 + I A+D D P + +D+ S FS++ G +++ + LDYE+ R ++ Sbjct: 2010 VLTSITANDVDTNPPLTYSFGDSPDEDAKSYFSIDRYSG----KVILIKPLDYEA-RHEF 2064 Query: 764 ELVIRAASPPLWNDVRVEILVTDVNDNAP 792 +L I A+ + + VTDVNDN P Sbjct: 2065 QLRILASDSAHVARTLLTVRVTDVNDNPP 2093 Score = 294 bits (721), Expect = 3e-77 Identities = 262/937 (27%), Positives = 433/937 (46%), Gaps = 98/937 (10%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 H ++VLD ND++P+F Q YE + E G+ + + ATD D G NA V Y+ L+ + Sbjct: 771 HVIVSVLDANDNNPIFAKQLYEFQIEENMRRGSVIGLITATDADAGINAVVRYS--LIPS 828 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 +T F+I+ SG + TR LDRE + Y ++V+A DQ +P Sbjct: 829 NT-------------------SFQINPISGEITTRDRLDRETKSIYDLVVEARDQGTPYR 869 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 SS +I + I+D NDN P+ + + VSV E+ + + +++A D D G N++ Sbjct: 870 ---SSRVSIKIKILDVNDNSPEIVDPQEDVVSVREEQPI--GTEVVRVRAIDRDYGVNAS 924 Query: 187 IRYAIIGG---NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 I Y+I+ G + F+ID ++G + +LD+E+ YRL + A D G P R L Sbjct: 925 ITYSILKGRDSDGHGMFTIDPITGLIRTKASLDHEEKTIYRLAVAATDNGKPPRQTVRLL 984 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN-------AELTYTM 296 I + D+NDN P F +S + E+V +G+ I + + + N +TYT+ Sbjct: 985 RIEVLDLNDNRPTFTSSSLVFRLREDVGVGHVIGSISGNEQSDLENLITSSNDLHITYTL 1044 Query: 297 TDKDYTGNV-DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA--TDGGDPPRSATATXX 353 T T ++ + ID SG + + LDRE Q++Y++ + A T + P+S+ T Sbjct: 1045 T--PLTNDIAEGAFDIDRNSGKLVVARSLDREQQSEYRMEIRALDTSASNNPQSSAVTVK 1102 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGR 411 + V ++ED G+ V TATD D + + Y I+ T + Sbjct: 1103 IEIADVNDNPPKWPSDPMNVYISEDAAVGSVVFNFTATDNDSGTNAEIKYNISKPATAQK 1162 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR-----SDTAMVQINITDANNYA 466 + + G +T+ PLD+++ + ++L V ATD + +A +I +TD N+ + Sbjct: 1163 EFFSIDSLTGSLTLLAPLDYEETKEFLLIVQATDQSSNVTERMTTSATARIMVTDVNDNS 1222 Query: 467 PVF---ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523 P F + T V + + V V A D D G N ++ Y + S NE D++ Sbjct: 1223 PKFVVPQAQDTTVYVSDSMEVNHIVSHVVAIDRDSGENGRVVYKIVS--GNE-----DER 1275 Query: 524 FVINPQTGAI------TTNKLLD--RETMSG-YLLTVTARDGGVP-SLSDTTDVEISVVD 573 F I+P TG + ++N + D + +++G Y L +TA D G P S +++ + + Sbjct: 1276 FAIDPDTGFVKLAKPFSSNFIADNSKNSITGRYNLVITATDQGTPRSKEAKITIQVVIQN 1335 Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633 ++N P F + +Y NI E+ G+ V +V A + N + YE+ PK + FV+D Sbjct: 1336 TSNNPPRFLESVYHINITENVPTGSFVVRVSAKSYNDNGNANLTYEI-PKGVGDDHFVVD 1394 Query: 634 PASGVIRTNKALDRES--------VATHDLKAVAIDGGTP---PQSSTVIVHIKIEDIND 682 G++ T DRES T + + GT Q + ++I D+ND Sbjct: 1395 SVRGIVTTRGTFDRESKDMYTVPIYVTEQNRFKSAASGTSKDMSQFDVATLVVRITDVND 1454 Query: 683 SPPVF-ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741 P F C + ENS + + I + A D DEG N + YSI GG+ N FS++ Sbjct: 1455 HAPEFLPGSCYPLAVPENSEL-SVIHTVVASDADEGLNGEITYSISGGNIGNKFSIDMNT 1513 Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRA---ASPPL-WNDVRVEILVTDVNDNAPVMKDF 797 G+ +T LD E +Y L I A SP + + V D NDN P + Sbjct: 1514 GA-----LTARPLDREI-HARYVLQITAQDRGSPTSHQGHCNITVRVEDENDNDPKFELQ 1567 Query: 798 QIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQ 854 + I +D P+G V A DAD + ++ Y L+ L ++ +G +T + Sbjct: 1568 KYIATIDEDA-PIGTTVLTVKAVDADIGINARIVYS-LANVTEWLFDIDSKSGVITTAGH 1625 Query: 855 LNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEM 891 + + V TDG + V++I ++ Sbjct: 1626 FDRERQSIYNFMVVATDGGRYNARSQSVQVQVIIADV 1662 Score = 286 bits (701), Expect = 7e-75 Identities = 228/753 (30%), Positives = 356/753 (47%), Gaps = 54/753 (7%) Query: 153 KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQM-QFSIDSLSGDVSL 211 K TV V + V + + ATD D G N+ + Y + G ++ +F I S +G+V + Sbjct: 240 KLGTVMVRRSVDQPPVAVHSDVSATDPDCGVNAMVNYTLGEGYKKITEFEIRSSTGEVCI 299 Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271 LDYE SY I A D G S T + I + DVNDN P FY + S+ E++P Sbjct: 300 AAELDYETRNSYEFPIIATDRG--GLSTTAMVKIQLTDVNDNRPTFYPREYNVSLRESMP 357 Query: 272 ----IGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS--GQLD 325 + +V + A D+D G ++Y + GN +D +G ++ + L Sbjct: 358 TNSLLSTPVVVIVATDSDSGSFGTISYRIV----AGNEAGIFRMDRLTGEIFVARPNMLS 413 Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 +Q ++L ++A+DGG + A F +Y + ED T V Sbjct: 414 SRSQPYHRLNISASDGGGLRSTHDAEVFISVIDATQRPPIFDKPRYTYYVKEDVKKNTVV 473 Query: 386 VTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443 T++AT ++ +R + Y I G+ G F+I +G I VA LD + + + +L + A Sbjct: 474 GTVSATSSNSGSRGSIRYFIYSGDPDGYFAIDPVSGN--IRVASTLDHETKPQVLLNIQA 531 Query: 444 TDSGGRS-DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502 T + V I+I D N+ P FE++ SV E+ IG+ + +A D D G++ Sbjct: 532 TSGDPPAYGHTQVNIDIEDVNDNPPEFESSTVRISVPENVEIGSPLYAANAHDKDSGMSG 591 Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 ITY LS+ + A + F I+ ++G ++ + LD ET+ + L VTA D G+PSLS Sbjct: 592 VITYRLSN--NGPATGN---LFSIDSRSGHLSLARPLDYETVQRHTLIVTASDSGIPSLS 646 Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-- 620 + + V DVNDN PVF++ Y + E + + QV A DAD G N R+ Y + Sbjct: 647 TNLTILVEVQDVNDNAPVFERSEYAIKVSESTPSNSQIMQVTAVDADTGNNARLTYRILG 706 Query: 621 -DPKDREEGS------------FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 D + R S F I P SG I LDRE +++ + D G P Sbjct: 707 DDQRTRTGKSSSKASEANTPEIFGIFPNSGWIYLRTKLDREDQERYNITVIVSDNGVPTL 766 Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 ++T V + + D ND+ P+F F I EN G+ IG I A D D G NAVV YS+ Sbjct: 767 TATTHVIVSVLDANDNNPIFAKQLYEFQIEENMRRGSVIGLITATDADAGINAVVRYSLI 826 Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILV 784 + SF + G E+ T LD E+ + Y+LV+ A +P + V ++I + Sbjct: 827 --PSNTSFQINPISG----EITTRDRLDRET-KSIYDLVVEARDQGTPYRSSRVSIKIKI 879 Query: 785 TDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILSGNNAN--- 838 DVNDN+P + D Q + ++ P+G RV A D D V + Y IL G +++ Sbjct: 880 LDVNDNSPEIVDPQEDVVSVREEQPIGTEVVRVRAIDRDYGVNASITYSILKGRDSDGHG 939 Query: 839 LILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + ++ TG + L+ + + V+ TD Sbjct: 940 MFTIDPITGLIRTKASLDHEEKTIYRLAVAATD 972 Score = 282 bits (691), Expect = 1e-73 Identities = 246/828 (29%), Positives = 379/828 (45%), Gaps = 80/828 (9%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 + Q+ + D ND+ PVF+ ++ + G T+L + ATD D G N E+ Y++ Sbjct: 1653 VQVQVIIADVNDNKPVFDKYPFKEQIGALVQPGQTLLHISATDVDQGSNGEIVYSLN--- 1709 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 D NP +A FRI+ +GAL SL E + V A D+ +P Sbjct: 1710 -D--NPNNAK-------------FRINPNTGALSATQSLASENGRLLHIEVTARDKGNPP 1753 Query: 127 SDRLSSTATIHVNIIDDNDNYP--QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184 +T I + + D P +F +Y V++ E+ + + + A +D G Sbjct: 1754 Q---VATGLIELRVGDLQQELPALKFQNNSYKVNLVENTPI--GQTVLHLNAVRSD-GRR 1807 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKT--LDYEQ-----VRSYRLVIRAQDGGSPSR 237 I Y+ GN FSID+++G+V + + LDYE+ LV A+ GSP Sbjct: 1808 QKIIYSFGSGNEDGTFSIDAVTGEVKIRNSHNLDYERFSRLNTEGIDLVAVARTDGSPLL 1867 Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297 + + ++D NDNAPRF + SV E G +++V A+D D+G NA + Y + Sbjct: 1868 YGYCSIKVVLQDENDNAPRFTQQQYSASVWEGNNKGEFVIKVNAFDTDQGSNAHILYHIV 1927 Query: 298 DKDYTGNVDLPITIDPR-SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 D GN D I+P SG V T+ LDRE + KY+L V ATD G P + TAT Sbjct: 1928 D----GNHDNAFIIEPAFSGIVKTNIVLDREIRDKYKLKVIATDEGVPQMTGTATINVNV 1983 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG---NTRGRFS 413 F P + ++E GT + ++TA D D + L Y + + FS Sbjct: 1984 VDVNDNQPTFPPNSV-ISVSEATTVGTVLTSITANDVDTNPPLTYSFGDSPDEDAKSYFS 2042 Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAP 473 I +G+ + + +PLD++ + L + A+DS + T ++ + +TD N+ P F+ Sbjct: 2043 IDRYSGK--VILIKPLDYEARHEFQLRILASDSAHVART-LLTVRVTDVNDNPPQFQQIT 2099 Query: 474 YTASV-------FEDAPIGTTV---LVVSATDSDVGINAQITYSLSSEISNEAVAHH--- 520 Y A + F++ + + L+ TDS+ I + S+ N A + Sbjct: 2100 YHAMLNGTNFPRFKNPGTHSNISFSLITDDTDSNSNIAIIAVNATDSDSENNAAIRYTII 2159 Query: 521 --DQQFVINPQTGAITTNKLLDRETMSGYL-LTVTARDGGVPSLSDTTDVEISVVDVNDN 577 F I+ TG + N T SG L LT+TA D GVP LS +T V + + + Sbjct: 2160 PPSIGFAIDALTGQLFVNMSQVHRTRSGTLYLTITATDSGVPPLSSSTTVRLEMKSKSKA 2219 Query: 578 EPVFKQQLYTANIMEDALVGTSVSQV--GATDADVGLNGRIHYELDPKDREEGSFVIDPA 635 P F Q Y +I EDA G+ ++ + A V ++ I +E+ ++ F I Sbjct: 2220 NPHFIQSQYRLSINEDAPTGSVITNLIPKAIAEQVDVSSSIAFEI-IDGNDDNCFEISYP 2278 Query: 636 SGVIRTNKALDRESVATHDLKAVAIDGGTP------PQSSTVIVHIKIEDINDSPPVFES 689 SG I K+LDRE ++L+ V + G SS + V I +ED ND+ P F+ Sbjct: 2279 SGAILLVKSLDREKTDYYELRLVVTEPGATMMYKGMNMSSAIRVTITVEDANDNAPEFQP 2338 Query: 690 DCLTFYISENSPIGTTIGEIRAHDPD--EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747 ISE +PI +IG+I A D D PN+ V Y I G+D FS++ G Sbjct: 2339 GPYEVAISETAPIKYSIGQISAVDADLLNSPNSEVVYQIVSGNDGGWFSIDLITGL---- 2394 Query: 748 LVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE---ILVTDVNDNAP 792 L +LDY+ ++ LVIRA + V I +TD NDN P Sbjct: 2395 LYINNNLDYDRGPTQFNLVIRACDSHVLPKCSVHPFVINLTDENDNEP 2442 Score = 266 bits (653), Expect = 5e-69 Identities = 256/917 (27%), Positives = 410/917 (44%), Gaps = 93/917 (10%) Query: 10 QINVLDCNDHSP-VFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68 +I +LD ND+SP + + Q+ SVRE GT V+ ++A D+D G NA + Y+I Sbjct: 876 KIKILDVNDNSPEIVDPQEDVVSVREEQPIGTEVVRVRAIDRDYGVNASITYSI------ 929 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 L D+ +F ID +G + T+ASLD E+ Y + V ATD P Sbjct: 930 -LKGRDSDG---------HGMFTIDPITGLIRTKASLDHEEKTIYRLAVAATDNGKPPRQ 979 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD------VG 182 + + + ++D NDN P F+ + + ED+ V VI I + Sbjct: 980 ---TVRLLRIEVLDLNDNRPTFTSSSLVFRLREDVGV--GHVIGSISGNEQSDLENLITS 1034 Query: 183 ANSA-IRYAIIGGNTQMQ---FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-- 236 +N I Y + + F ID SG + + ++LD EQ YR+ IRA D + + Sbjct: 1035 SNDLHITYTLTPLTNDIAEGAFDIDRNSGKLVVARSLDREQQSEYRMEIRALDTSASNNP 1094 Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 +S+ + I I DVNDN P++ + +SE+ +G + A D D G NAE+ Y + Sbjct: 1095 QSSAVTVKIEIADVNDNPPKWPSDPMNVYISEDAAVGSVVFNFTATDNDSGTNAEIKYNI 1154 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-----PRSATAT 351 + K T + +ID +G + LD E ++ L+V ATD SATA Sbjct: 1155 S-KPATAQKEF-FSIDSLTGSLTLLAPLDYEETKEFLLIVQATDQSSNVTERMTTSATAR 1212 Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT-LTATDAD--EDNRLHYEITGGNT 408 Q D +V+ + A D D E+ R+ Y+I GN Sbjct: 1213 IMVTDVNDNSPKFVVPQAQDTTVYVSDSMEVNHIVSHVVAIDRDSGENGRVVYKIVSGNE 1272 Query: 409 RGRFSITSQNGRGLITVAQPL--DFKQER-------RYVLTVSATDSGG-RSDTAMV--Q 456 RF+I G + +A+P +F + RY L ++ATD G RS A + Q Sbjct: 1273 DERFAIDPDTG--FVKLAKPFSSNFIADNSKNSITGRYNLVITATDQGTPRSKEAKITIQ 1330 Query: 457 INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA 516 + I + +N P F + Y ++ E+ P G+ V+ VSA + NA +TY + + Sbjct: 1331 VVIQNTSNNPPRFLESVYHINITENVPTGSFVVRVSAKSYNDNGNANLTYEIPKGVG--- 1387 Query: 517 VAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTV---------TARDGGVPSLS--DTT 565 D FV++ G +TT DRE+ Y + + +A G +S D Sbjct: 1388 ----DDHFVVDSVRGIVTTRGTFDRESKDMYTVPIYVTEQNRFKSAASGTSKDMSQFDVA 1443 Query: 566 DVEISVVDVNDNEPVFKQ-QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624 + + + DVND+ P F Y + E++ + + V A+DAD GLNG I Y + + Sbjct: 1444 TLVVRITDVNDHAPEFLPGSCYPLAVPENSELSV-IHTVVASDADEGLNGEITYSISGGN 1502 Query: 625 REEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDS 683 F ID +G + T + LDRE A + L+ A D G+P + +++ED ND+ Sbjct: 1503 IGN-KFSIDMNTGAL-TARPLDREIHARYVLQITAQDRGSPTSHQGHCNITVRVEDENDN 1560 Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 P FE I E++PIGTT+ ++A D D G NA + YS+ + F ++++ G Sbjct: 1561 DPKFELQKYIATIDEDAPIGTTVLTVKAVDADIGINARIVYSLANVTEW-LFDIDSKSGV 1619 Query: 744 DKAELVTMVDLDYESPRKKYELVIRAASPPLWN----DVRVEILVTDVNDNAPVMKDFQI 799 + T D E + Y ++ A +N V+V++++ DVNDN PV + Sbjct: 1620 ----ITTAGHFDRER-QSIYNFMVVATDGGRYNARSQSVQVQVIIADVNDNKPVFDKYPF 1674 Query: 800 IFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNT 857 P + A D D ++ Y + N +N TG+++ + L + Sbjct: 1675 KEQIGALVQPGQTLLHISATDVDQGSNGEIVYSLNDNPNNAKFRINPNTGALSATQSLAS 1734 Query: 858 NVPKLATMEVSVTDGVN 874 +L +EV+ D N Sbjct: 1735 ENGRLLHIEVTARDKGN 1751 Score = 213 bits (521), Expect = 4e-53 Identities = 241/897 (26%), Positives = 384/897 (42%), Gaps = 85/897 (9%) Query: 10 QINVLDCNDHSPVFEMQQ--YEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 ++ V D P + Q Y+ ++ E G TVL L A D G+ ++ Y+ Sbjct: 1761 ELRVGDLQQELPALKFQNNSYKVNLVENTPIGQTVLHLNAVRSD-GRRQKIIYSFGSGNE 1819 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 D DA +++ +D + L +D VAR TD SP+ Sbjct: 1820 DGTFSIDAVTGEVK----IRNSHNLDYERFSRLNTEGIDLVAVAR-------TD-GSPL- 1866 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 L +I V + D+NDN P+F+++ Y+ SV E + + + K+ A D D G+N+ I Sbjct: 1867 --LYGYCSIKVVLQDENDNAPRFTQQQYSASVWEGNNKGE--FVIKVNAFDTDQGSNAHI 1922 Query: 188 RYAIIGGNTQMQFSID-SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 Y I+ GN F I+ + SG V LD E Y+L + A D G P + T + +N Sbjct: 1923 LYHIVDGNHDNAFIIEPAFSGIVKTNIVLDREIRDKYKLKVIATDEGVPQMTGTATINVN 1982 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + DVNDN P F + SVSE +G + + A D D N LTY+ D + Sbjct: 1983 VVDVNDNQPTFPPNSVI-SVSEATTVGTVLTSITANDVD--TNPPLTYSFGDSP-DEDAK 2038 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG----------------DPPRSATA 350 +ID SG V LD E + ++QL + A+D +PP+ Sbjct: 2039 SYFSIDRYSGKVILIKPLDYEARHEFQLRILASDSAHVARTLLTVRVTDVNDNPPQFQQI 2098 Query: 351 TXXXXXXXXXXXXXXFMPGQYE---VELAEDEPPGTP---VVTLTATDADEDNRLHYEIT 404 T PG + L D+ ++ + ATD+D +N T Sbjct: 2099 TYHAMLNGTNFPRFK-NPGTHSNISFSLITDDTDSNSNIAIIAVNATDSDSENNAAIRYT 2157 Query: 405 GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDA 462 F+I + G+ + ++Q + Y LT++ATDSG S + V++ + Sbjct: 2158 IIPPSIGFAIDALTGQLFVNMSQVHRTRSGTLY-LTITATDSGVPPLSSSTTVRLEMKSK 2216 Query: 463 NNYAPVFENAPYTASVFEDAPIGTTV--LVVSATDSDVGINAQITYSLSSEISNEAVAHH 520 + P F + Y S+ EDAP G+ + L+ A V +++ I + + + Sbjct: 2217 SKANPHFIQSQYRLSINEDAPTGSVITNLIPKAIAEQVDVSSSIAFEIID-------GND 2269 Query: 521 DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP------SLSDTTDVEISVVDV 574 D F I+ +GAI K LDRE Y L + + G ++S V I+V D Sbjct: 2270 DNCFEISYPSGAILLVKSLDREKTDYYELRLVVTEPGATMMYKGMNMSSAIRVTITVEDA 2329 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV--GLNGRIHYELDPKDREEGSFVI 632 NDN P F+ Y I E A + S+ Q+ A DAD+ N + Y++ + G F I Sbjct: 2330 NDNAPEFQPGPYEVAISETAPIKYSIGQISAVDADLLNSPNSEVVYQI-VSGNDGGWFSI 2388 Query: 633 DPASGVIRTNKALDRESVATH-DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691 D +G++ N LD + T +L A D P+ S I + D ND+ P F Sbjct: 2389 DLITGLLYINNNLDYDRGPTQFNLVIRACDSHVLPKCSVHPFVINLTDENDNEPQFPVPE 2448 Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751 ++ EN PIG +I RA D D G V+YSI S S++ K + V+ Sbjct: 2449 YLEFVGENEPIGISIFTARATDMDRGEYGRVNYSIDNAMTSGYSSVDDGWKLFKVDSVSG 2508 Query: 752 V-----DLDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAP--VMKDFQIIFNN 803 V DYE + +Y +RA + V+V I++ ++ +P + ++ I Sbjct: 2509 VINSNAVFDYEE-KNRYSFTLRATDTGGKSKTVKVRIMIESRDEFSPQFTERTYRFILKT 2567 Query: 804 -YKDCFPVG-PFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 PVG G V A D D ++ Y++ + + +N TTG++ + +L+ Sbjct: 2568 PDTGHLPVGYVVGHVTATDRDRGPDGRIVYQLTTQH--PYFKMNRTTGAILVKKKLD 2622 Score = 179 bits (435), Expect = 1e-42 Identities = 169/598 (28%), Positives = 266/598 (44%), Gaps = 59/598 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVR-----EGASSGT-TVLTLKATDQDIGKNAEVEYTIEL 64 + V D ND+ P F+ Y A + + GT + ++ D N+ + I + Sbjct: 2083 VRVTDVNDNPPQFQQITYHAMLNGTNFPRFKNPGTHSNISFSLITDDTDSNSNIAI-IAV 2141 Query: 65 VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS-LDREKVARYTVLVKATDQA 123 D+ + +A + F ID +G L S + R + + + ATD Sbjct: 2142 NATDSDSENNAAIRYTIIPPSIG--FAIDALTGQLFVNMSQVHRTRSGTLYLTITATDSG 2199 Query: 124 SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI---SVTDNPVIAKIKATDAD 180 P LSS+ T+ + + + P F + Y +S++ED SV N +I K A D Sbjct: 2200 VPP---LSSSTTVRLEMKSKSKANPHFIQSQYRLSINEDAPTGSVITN-LIPKAIAEQVD 2255 Query: 181 VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP----- 235 V +S+I + II GN F I SG + LVK+LD E+ Y L + + G+ Sbjct: 2256 V--SSSIAFEIIDGNDDNCFEISYPSGAILLVKSLDREKTDYYELRLVVTEPGATMMYKG 2313 Query: 236 -SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD--EGVNAEL 292 + S+ ++ I + D NDNAP F ++ ++SE PI YSI ++ A DAD N+E+ Sbjct: 2314 MNMSSAIRVTITVEDANDNAPEFQPGPYEVAISETAPIKYSIGQISAVDADLLNSPNSEV 2373 Query: 293 TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET-QAKYQLLVTATDGGDPPRSATAT 351 Y + +GN +ID +G +Y + LD + ++ L++ A D P+ + Sbjct: 2374 VYQIV----SGNDGGWFSIDLITGLLYINNNLDYDRGPTQFNLVIRACDSHVLPKCSVHP 2429 Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTR 409 F +Y + E+EP G + T ATD D E R++Y I T Sbjct: 2430 FVINLTDENDNEPQFPVPEYLEFVGENEPIGISIFTARATDMDRGEYGRVNYSIDNAMTS 2489 Query: 410 GRFSITS-------QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDA 462 G S+ + G+I D++++ RY T+ ATD+GG+S T V+I I Sbjct: 2490 GYSSVDDGWKLFKVDSVSGVINSNAVFDYEEKNRYSFTLRATDTGGKSKTVKVRIMIESR 2549 Query: 463 NNYAPVFENAPYTASVFED----APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518 + ++P F Y + P+G V V+ATD D G + +I Y L+++ Sbjct: 2550 DEFSPQFTERTYRFILKTPDTGHLPVGYVVGHVTATDRDRGPDGRIVYQLTTQ------- 2602 Query: 519 HHDQQFVINPQTGAITTNKLLDRETMS-----GYLLTVTARDGGVPSLSDTTDVEISV 571 F +N TGAI K LD S L VTA G SL++ T VEIS+ Sbjct: 2603 --HPYFKMNRTTGAILVKKKLDDVAASLEAGRDISLVVTASSGRQGSLTNMTVVEISI 2658 Score = 93.1 bits (221), Expect = 1e-16 Identities = 81/311 (26%), Positives = 142/311 (45%), Gaps = 38/311 (12%) Query: 1 MSVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEY 60 M++ I I V D ND++P F+ YE ++ E A ++ + A D D+ + E Sbjct: 2314 MNMSSAIRVTITVEDANDNAPEFQPGPYEVAISETAPIKYSIGQISAVDADLLNSPNSEV 2373 Query: 61 TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREK-VARYTVLVKA 119 ++V+ + D F ID +G L +LD ++ ++ ++++A Sbjct: 2374 VYQIVSGN-----DGGW------------FSIDLITGLLYINNNLDYDRGPTQFNLVIRA 2416 Query: 120 TDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA 179 D S V + S + +N+ D+NDN PQF Y V E+ + + I +ATD Sbjct: 2417 CD--SHVLPKCSVHPFV-INLTDENDNEPQFPVPEYLEFVGENEPIGIS--IFTARATDM 2471 Query: 180 DVGANSAIRYAIIGGNTQ---------MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ 230 D G + Y+I T F +DS+SG ++ DYE+ Y +RA Sbjct: 2472 DRGEYGRVNYSIDNAMTSGYSSVDDGWKLFKVDSVSGVINSNAVFDYEEKNRYSFTLRAT 2531 Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRF----YTSLFQESVSENVPIGYSIVRVQAYDADE 286 D G S++ +++I RD + +P+F Y + + + ++P+GY + V A D D Sbjct: 2532 DTGGKSKTVKVRIMIESRD--EFSPQFTERTYRFILKTPDTGHLPVGYVVGHVTATDRDR 2589 Query: 287 GVNAELTYTMT 297 G + + Y +T Sbjct: 2590 GPDGRIVYQLT 2600 >UniRef50_UPI00015A7221 Cluster: UPI00015A7221 related cluster; n=1; Danio rerio|Rep: UPI00015A7221 UniRef100 entry - Danio rerio Length = 3995 Score = 370 bits (910), Expect = e-100 Identities = 264/900 (29%), Positives = 447/900 (49%), Gaps = 68/900 (7%) Query: 3 VPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 V FC +I + D ND+ P F+ +Y+ S++ + G+ V+ + A D D GKNA+V YT+ Sbjct: 2551 VGFCT-VKIILTDENDNVPQFKASEYDISIQSTVNKGSPVIQIMAYDADEGKNADVTYTV 2609 Query: 63 ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122 E AD + +D+ ++ +G + + SL + + VKA D Sbjct: 2610 E--EADEV---------------TEDIIEVNPFTGVVSVKESLVGLENKIFNFKVKARDG 2652 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 P +S+ + V ++ P+F+E Y+ S ED+ P+ +I AD Sbjct: 2653 GFPF---YNSSVPVQVKVVPPEIILPRFTEPLYSFSASEDL-----PIGYEIGTVKAD-- 2702 Query: 183 ANSAIRYAIIGGNT-----QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237 A+ + Y+++ GNT ++ F+ID G V L +D+E+ + Y++ + AQ G+ + Sbjct: 2703 ADMPLIYSLVNGNTLDSNKELSFAIDKDGGTVVLQNNIDHEKTKMYKIDVIAQ--GNHNG 2760 Query: 238 SNTTQLL---INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294 +N L+ I ++DVNDN P F ++ ++EN+P G ++++V A DAD +N E++Y Sbjct: 2761 TNVASLVSVHIEVQDVNDNKPMFEADTYKAFLAENLPSGTTVIQVTANDADANINGEVSY 2820 Query: 295 TM-TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSATATX 352 T+ + D G++ ID ++GW+ T + D ET+ ++ V ATD GD +SA+ Sbjct: 2821 TLEPESDDIGDM---FAIDSQTGWITTLKEADSETKQLHRFFVVATDHGDALKQSASVLV 2877 Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTR 409 F Y+ + E+ PG +VTLT D D E+ ++ IT G+ Sbjct: 2878 EVTLTDENDNPPQFTEELYQGSILENSRPGENIVTLTTADKDVSAENRQIVCYITDGDPL 2937 Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVF 469 G+FS+T+ + PLD + + +Y L + ATD G +A V++++ D N+ +P Sbjct: 2938 GQFSVTAVGEEWTVISKSPLDREDKDKYTLKIIATD-GRFQTSANVEVHVLDLNDNSPFC 2996 Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 E YT +V E++ G +L +SA+D D+G N Q++++L + +F ++P+ Sbjct: 2997 EQLQYTEAVMENSSSGKVILKISASDPDIGTNGQVSFTLHGP--------NADKFHLDPK 3048 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589 TG + T +LDRE Y L V A DGG S DV + V D+NDN P F Y Sbjct: 3049 TGELFTLAVLDREREKEYDLVVKATDGG--GRSCQADVTLMVQDMNDNPPQFSTSHYEVT 3106 Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES 649 + ++ + T ++ + A D D G+N + Y L D G F +D SGV+R ++L E+ Sbjct: 3107 VFDNTTIRTPIAVIYAKDPDTGINSEVRYSLQGAD--SGFFSLDEISGVLRLERSLADET 3164 Query: 650 VATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 +T+++K A D G P S ++ + + ++D P+F S + I+E+S +G+ + Sbjct: 3165 KSTYEMKVKATDRGLPRHLFSFAMITVHVVILSDYQPLFLSSEYSVQIAESSQVGSEVIS 3224 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768 + A D N V YSI G++ F + G L LD+E R+ Y V Sbjct: 3225 VSALTKDATENEPVRYSIISGNEDGRFMINPVTGL----LSVKAALDFERCREYYLSVEG 3280 Query: 769 AASPPLWNDVRVEIL-VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTD 825 A PL +D+ + I+ +TDVNDN PV +D P +V A D D + Sbjct: 3281 ARGKPLLSDIAMVIINITDVNDNPPVFNRSSYSTVIPEDISPGEMALQVRAIDLDGPPNN 3340 Query: 826 KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSV 884 + Y I+SG+ ++ TG +TL L+ ++ V D G + + +Q++V Sbjct: 3341 FIIYSIVSGDPKQQFSIDPRTGFITLRSMLDREEITHYSLTVQAADEGDPPLSSAVQVTV 3400 Score = 365 bits (897), Expect = 1e-98 Identities = 281/949 (29%), Positives = 453/949 (47%), Gaps = 65/949 (6%) Query: 2 SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 +V + I V D ND+ P+FE Y+A + E SGTTV+ + A D D N EV YT Sbjct: 2762 NVASLVSVHIEVQDVNDNKPMFEADTYKAFLAENLPSGTTVIQVTANDADANINGEVSYT 2821 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121 +E PE + D+F ID ++G + T D E + V ATD Sbjct: 2822 LE--------PES---------DDIGDMFAIDSQTGWITTLKEADSETKQLHRFFVVATD 2864 Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181 + S++ + V + D+NDN PQF+E+ Y S+ E+ +N I + D DV Sbjct: 2865 HGDALKQ--SASVLVEVTLTDENDNPPQFTEELYQGSILENSRPGEN--IVTLTTADKDV 2920 Query: 182 GA-NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRS 238 A N I I G+ QFS+ ++ + +++ LD E Y L I A DG + + Sbjct: 2921 SAENRQIVCYITDGDPLGQFSVTAVGEEWTVISKSPLDREDKDKYTLKIIATDGRFQTSA 2980 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 N +++ D+NDN+P + E+V EN G I+++ A D D G N ++++T+ Sbjct: 2981 NVE---VHVLDLNDNSPFCEQLQYTEAVMENSSSGKVILKISASDPDIGTNGQVSFTL-- 3035 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358 + N D +DP++G ++T LDRE + +Y L+V ATDGG RS A Sbjct: 3036 --HGPNAD-KFHLDPKTGELFTLAVLDREREKEYDLVVKATDGGG--RSCQADVTLMVQD 3090 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITS 416 F YEV + ++ TP+ + A D D ++ + Y + G ++ G FS+ Sbjct: 3091 MNDNPPQFSTSHYEVTVFDNTTIRTPIAVIYAKDPDTGINSEVRYSLQGADS-GFFSLDE 3149 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAP 473 +G ++ + + L + + Y + V ATD G AM+ +++ ++Y P+F ++ Sbjct: 3150 ISG--VLRLERSLADETKSTYEMKVKATDRGLPRHLFSFAMITVHVVILSDYQPLFLSSE 3207 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 Y+ + E + +G+ V+ VSA D N + YS+ S NE D +F+INP TG + Sbjct: 3208 YSVQIAESSQVGSEVISVSALTKDATENEPVRYSIIS--GNE-----DGRFMINPVTGLL 3260 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593 + LD E Y L+V G P LSD V I++ DVNDN PVF + Y+ I ED Sbjct: 3261 SVKAALDFERCREYYLSVEGARGK-PLLSDIAMVIINITDVNDNPPVFNRSSYSTVIPED 3319 Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653 G QV A D D N I Y + D ++ F IDP +G I LDRE + + Sbjct: 3320 ISPGEMALQVRAIDLDGPPNNFIIYSIVSGDPKQ-QFSIDPRTGFITLRSMLDREEITHY 3378 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713 L A D G PP SS V V + + D+ND+PP+F + + E +G+ I ++ D Sbjct: 3379 SLTVQAADEGDPPLSSAVQVTVTVSDVNDNPPMFSKINHSLIVQEGEAVGSGILQLLVTD 3438 Query: 714 PDEGPNAV-VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS- 771 D N + I G++ SF + D+ L+++ + ++ L I+ Sbjct: 3439 RDTPQNGPPFSFHIVSGNEDRSFHI------DQGGLLSVSSQLRRRGKPQHLLKIQVTDS 3492 Query: 772 --PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQY 829 PPL + V+I +T+ + P + +I ++ A D D D L Y Sbjct: 3493 GHPPLSSICVVKINITEQSRYPPTVNPLEIFITTAGGPILKSVISKLHATDQDPQDVLSY 3552 Query: 830 RILS-GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLIT 888 +++S G + L ++ G + + L+ P L + VSVTDG I A +++ V T Sbjct: 3553 KLVSEGQDKGLFSVDTVDGKIVVEKNLD---PGLYHLNVSVTDGKFSIWAGVKVHVWAAT 3609 Query: 889 EEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQ 937 ++ L T++L ++AE+F+S LA + P++ ++I S+Q Sbjct: 3610 QQNLDQGFTLQLAGISAEEFVSDHWRGLQRSLAQELNIPRQELHIASLQ 3658 Score = 317 bits (778), Expect = 3e-84 Identities = 264/893 (29%), Positives = 405/893 (45%), Gaps = 61/893 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I+V D ND++PVF+ Y A V EG GT+VL + A D+D KNAE Y +L+ ++ Sbjct: 2249 EIDVEDINDNAPVFQNLSYVADVFEGLPIGTSVLQVSAVDRDADKNAEATY--QLIDKES 2306 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 F ID SG L+T LD E ++T+ VKATD+ P Sbjct: 2307 ------------------HFFEIDPLSGVLVTTQVLDYESTQQFTLKVKATDKGVPP--- 2345 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LS A I VN+ID NDN P FSE +Y S+DE T ++ K++A+D D + ++Y Sbjct: 2346 LSGEAHIIVNVIDVNDNPPDFSEPSYRASLDE--MATCGNIVIKVQASDPD--SKDDLQY 2401 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I+ GN F+I+ SG +S Y L + DG T + I++ + Sbjct: 2402 KILSGNEGRYFAINESSGLISFSNVCKRNLDPFYNLTVAVSDGVF---QKTAPVNIDMTN 2458 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 N +P F ++++ ++EN +G ++R+ A D D+G + YT+ +K D Sbjct: 2459 GNKYSPYFTQNIYEADLAENAEVGTRVIRLAAIDPDDGPYGSVDYTIINK----LADEKF 2514 Query: 310 TIDPRSGWVYTSGQLDRE--TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 I+ G + TS LDRE +Q + + A DGG R T F Sbjct: 2515 AIN-EDGQIVTSQPLDRENPSQRVIAIKIMAKDGGG--RVGFCTVKIILTDENDNVPQFK 2571 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITV 425 +Y++ + G+PV+ + A DADE + Y + + I G+++V Sbjct: 2572 ASEYDISIQSTVNKGSPVIQIMAYDADEGKNADVTYTVEEADEVTEDIIEVNPFTGVVSV 2631 Query: 426 AQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 + L + + + V A D G + + VQ+ + P F Y+ S ED P Sbjct: 2632 KESLVGLENKIFNFKVKARDGGFPFYNSSVPVQVKVVPPEIILPRFTEPLYSFSASEDLP 2691 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 IG + V A D+D+ + YSL + N ++ + F I+ G + +D E Sbjct: 2692 IGYEIGTVKA-DADM----PLIYSLVN--GNTLDSNKELSFAIDKDGGTVVLQNNIDHEK 2744 Query: 544 MSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 Y + V A+ +++ V I V DVNDN+P+F+ Y A + E+ GT+V Q Sbjct: 2745 TKMYKIDVIAQGNHNGTNVASLVSVHIEVQDVNDNKPMFEADTYKAFLAENLPSGTTVIQ 2804 Query: 603 VGATDADVGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKALDRESVATHDLKAVAID 661 V A DAD +NG + Y L+P+ + G F ID +G I T K D E+ H VA D Sbjct: 2805 VTANDADANINGEVSYTLEPESDDIGDMFAIDSQTGWITTLKEADSETKQLHRFFVVATD 2864 Query: 662 -GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-EGPN 719 G QS++V+V + + D ND+PP F + I ENS G I + D D N Sbjct: 2865 HGDALKQSASVLVEVTLTDENDNPPQFTEELYQGSILENSRPGENIVTLTTADKDVSAEN 2924 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR 779 + I GD FS+ T G ++ +++ LD E + KY L I A Sbjct: 2925 RQIVCYITDGDPLGQFSV-TAVG-EEWTVISKSPLDRED-KDKYTLKIIATDGRFQTSAN 2981 Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRI-LSGNNAN 838 VE+ V D+NDN+P + Q ++ ++ A D D+ Q L G NA+ Sbjct: 2982 VEVHVLDLNDNSPFCEQLQYTEAVMENSSSGKVILKISASDPDIGTNGQVSFTLHGPNAD 3041 Query: 839 LILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEM 891 L+ TG + L+ K + V TDG Q V L+ ++M Sbjct: 3042 KFHLDPKTGELFTLAVLDREREKEYDLVVKATDGGGR---SCQADVTLMVQDM 3091 Score = 294 bits (722), Expect = 2e-77 Identities = 248/810 (30%), Positives = 374/810 (46%), Gaps = 64/810 (7%) Query: 10 QINVLDCNDH--SPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 +I VLD N++ P+F + A+V E A GT+VLTL A D D+G++ V Y I Sbjct: 1009 EIEVLDVNENLNRPLFGEMVHTAAVMEDAKIGTSVLTLTAVDNDLGRDGVVRYYIH---- 1064 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 D VF +D +G + T LDRE V Y + V A D + Sbjct: 1065 ------DGSGLG---------VFTVDEETGVIQTAGLLDREVVPHYWLTVYAKDLGTIP- 1108 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 L S +++ + D NDN P+ S+ Y SV E++ D V+ K+ ATD D + + Sbjct: 1109 --LVSWTEVYIEVWDINDNPPELSQPVYFGSVQENLP-KDKSVL-KVSATDMDKSSEGKL 1164 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 + I+ ++ F+IDS +G +S + +LD EQ + + + D G P S+T ++I + Sbjct: 1165 AFQILDSQ-RIYFTIDSKTGVISTLSSLDREQKAEHIIEVMVSDKGEPPLSSTATVVIEV 1223 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIG--YSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 D NDN+P+F LFQ + E I R+ A D D G N +TY++ D + G Sbjct: 1224 LDENDNSPQFSHKLFQIKLPERQSTAEPQDIYRMVARDDDVGPNGMITYSLEDNN-EGRF 1282 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLL-VTATDGGDPPRSATATXXXXXXXX---XX 361 D I P +G V GQ R Y +L + ATD G+PPR + + Sbjct: 1283 D----IHPDTGVVTARGQFVR---GNYSILTIQATDQGNPPRMSKSRLHVEWLPQPEPSS 1335 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421 F + + E +P T +V + T+ + N L ++I GG+ F I + G Sbjct: 1336 DVLAFDEPPFNYVVMETDPV-TDMVGIIRTEIPK-NLLLFDIIGGDEEQDFYI--EKNTG 1391 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 I A+ L+ ++ Y LTV TD G ++ T I + D N + P+F + Y V ED Sbjct: 1392 SIVKARRLNAGKKSHYNLTVRVTD-GFQTITTQAYIQVVDINEHRPMFLKSLYEVRVPED 1450 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 +L +SA D+D ++ + YS+ S ++ E++ + F ++ ++G + + LD Sbjct: 1451 TSPWKEILHISAHDADA--SSGLFYSIHSSLNPESLKY----FHLDQRSGVLVLKEELDY 1504 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 ET+S + L V RD +P + V + V D ND+ P F Y I AL GT V Sbjct: 1505 ETISTHTLIVMVRDDKIPIKKNFAKVVVHVEDCNDHIPSFLDTHYEGIISNLALTGTEVL 1564 Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 +V A D D G N I Y +G+F ID +G IR + ALDR + L A D Sbjct: 1565 RVKALDKDTGSNADIVYSFHSGGNVDGAFKIDQGTGSIRVSDALDRLPQEHYHLTVKATD 1624 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 G P +S+ V I I+ +PP F S ISE P G+ + + A P Sbjct: 1625 QGFPQRSALCPVTITIKLSEFTPPRFSSKEYITEISEAMPPGSPVLSVSARCPSS----- 1679 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP-LWNDVRV 780 V Y I GD + +F + G L LD+E Y L I A + + +D V Sbjct: 1680 VLYRINEGDPNGTFHININSGL----LSVKNALDFEQ-HSSYHLQISATNTAGISSDAVV 1734 Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFPV 810 + V D NDNAPV + + + PV Sbjct: 1735 FVYVIDANDNAPVFHQ-DVYYGQISESAPV 1763 Score = 291 bits (714), Expect = 2e-76 Identities = 267/939 (28%), Positives = 423/939 (45%), Gaps = 76/939 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + + ND+ PVFE AS+ + G + + A D D + ++ Y IE D L Sbjct: 546 ITMTNVNDNVPVFERVACNASIPRDFAVGEIIAEISALDLD--ELQQIVYRIESGNDDGL 603 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQAS----- 124 D + ++ S L + D +A TV V TD Sbjct: 604 FSIDPVSGIIKLAKAIPSNYKDTENSLYTLKITATDGTYIADPNTVTVSITDNGEGAITH 663 Query: 125 --------PVSDRLSSTATIHVNIIDD---------NDNYPQFSEKTY-TVSVDEDISVT 166 ++++L + +NI ++ N + P+F T ++ + ED ++ Sbjct: 664 CEETGITRQLTEKLIESFRPSLNIKEEESISDVHIINQHSPKFVISTPGSIDIREDFAL- 722 Query: 167 DNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLV 226 N + + ATD D G N + Y+I GN F+ID +GD+ ++ LD EQ Y L Sbjct: 723 -NRSVLQFNATDNDSGFNGKLVYSISSGNEDGCFTIDVNAGDLKVICALDREQKEFYILN 781 Query: 227 IRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE 286 I D G P S L +NI D NDN P F S + ++ EN + SI +V A D D Sbjct: 782 ITVYDLGYPQTSTWKLLAVNILDANDNPPLFSQSRYVVTIPENTEVDKSIFKVNAVDFDL 841 Query: 287 GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG--DP 344 N Y++ +T DL I+ +G V G LDRET +Y L + A D DP Sbjct: 842 DNNGAFKYSL----FT-FTDL-FQIEEDTGVVKVIGPLDRETFRRYDLTIEARDQAKPDP 895 Query: 345 PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYE 402 + F+P Y++++ ED PPGT ++ + + D D ++ + Y Sbjct: 896 QLFSFTDVVVVLEDINDNPPKFVPTVYKIKVPEDVPPGTVLLWVESFDLDLESGGVISYN 955 Query: 403 ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINI 459 + + G F + + G +T+ + LDF++ + Y LTV A D G S + ++I + Sbjct: 956 LKNSES-GTFFLDTSTGS--LTLERELDFEKRQFYNLTVRAVDHGKPRSLSSSCFIEIEV 1012 Query: 460 TDANN--YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517 D N P+F +TA+V EDA IGT+VL ++A D+D+G + + Y + + S V Sbjct: 1013 LDVNENLNRPLFGEMVHTAAVMEDAKIGTSVLTLTAVDNDLGRDGVVRYYI-HDGSGLGV 1071 Query: 518 AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577 F ++ +TG I T LLDRE + Y LTV A+D G L T+V I V D+NDN Sbjct: 1072 ------FTVDEETGVIQTAGLLDREVVPHYWLTVYAKDLGTIPLVSWTEVYIEVWDINDN 1125 Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637 P Q +Y ++ E+ SV +V ATD D G++ +++ D + F ID +G Sbjct: 1126 PPELSQPVYFGSVQENLPKDKSVLKVSATDMDKSSEGKLAFQI--LDSQRIYFTIDSKTG 1183 Query: 638 VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697 VI T +LDRE A H ++ + D G PP SST V I++ D ND+ P F + Sbjct: 1184 VISTLSSLDREQKAEHIIEVMVSDKGEPPLSSTATVVIEVLDENDNSPQFSHKLFQIKLP 1243 Query: 698 ENSPIG--TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755 E I + A D D GPN ++ YS++ ++ F + G +V Sbjct: 1244 ERQSTAEPQDIYRMVARDDDVGPNGMITYSLEDNNEGR-FDIHPDTG--------VVTAR 1294 Query: 756 YESPRKKYE-LVIRA---ASPPLWNDVRVEI-LVTDVNDNAPVMKDFQIIFNN-YKDCFP 809 + R Y L I+A +PP + R+ + + ++ V+ + FN + P Sbjct: 1295 GQFVRGNYSILTIQATDQGNPPRMSKSRLHVEWLPQPEPSSDVLAFDEPPFNYVVMETDP 1354 Query: 810 VGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSV 869 V + + + L + I+ G+ + + TGS+ + +LN + V V Sbjct: 1355 VTDMVGIIRTEIP-KNLLLFDIIGGDEEQDFYIEKNTGSIVKARRLNAGKKSHYNLTVRV 1413 Query: 870 TDGVNEIKAMMQLSVRLITEE--MLLNSI-TVRLNDMTA 905 TDG I + V I E M L S+ VR+ + T+ Sbjct: 1414 TDGFQTITTQAYIQVVDINEHRPMFLKSLYEVRVPEDTS 1452 Score = 283 bits (694), Expect = 5e-74 Identities = 247/880 (28%), Positives = 400/880 (45%), Gaps = 70/880 (7%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 H +NV+D ND+ P F Y AS+ E A+ G V+ ++A+D D +++Y I Sbjct: 2351 HIIVNVIDVNDNPPDFSEPSYRASLDEMATCGNIVIKVQASDPD--SKDDLQYKI----- 2403 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 L+ + F I+ SG + R Y + V +D Sbjct: 2404 --LSGNEGR------------YFAINESSGLISFSNVCKRNLDPFYNLTVAVSDGV---- 2445 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 TA +++++ + N P F++ Y + E+ V + ++ A D D G ++ Sbjct: 2446 --FQKTAPVNIDMTNGNKYSPYFTQNIYEADLAENAEVGTR--VIRLAAIDPDDGPYGSV 2501 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYE--QVRSYRLVIRAQDGGSPSRSNTTQLLI 245 Y II +F+I+ G + + LD E R + I A+DGG T ++++ Sbjct: 2502 DYTIINKLADEKFAINE-DGQIVTSQPLDRENPSQRVIAIKIMAKDGGGRVGFCTVKIIL 2560 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 D NDN P+F S + S+ V G ++++ AYDADEG NA++TYT+ + D Sbjct: 2561 T--DENDNVPQFKASEYDISIQSTVNKGSPVIQIMAYDADEGKNADVTYTVEEADEV-TE 2617 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 D+ I ++P +G V L + V A DGG P +++ Sbjct: 2618 DI-IEVNPFTGVVSVKESLVGLENKIFNFKVKARDGGFPFYNSSVPVQVKVVPPEIILPR 2676 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT---RGRFSITSQNGRGL 422 F Y +ED P G + T+ AD D L Y + GNT S G Sbjct: 2677 FTEPLYSFSASEDLPIGYEIGTV---KADADMPLIYSLVNGNTLDSNKELSFAIDKDGGT 2733 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTA---MVQINITDANNYAPVFENAPYTASVF 479 + + +D ++ + Y + V A + ++ A V I + D N+ P+FE Y A + Sbjct: 2734 VVLQNNIDHEKTKMYKIDVIAQGNHNGTNVASLVSVHIEVQDVNDNKPMFEADTYKAFLA 2793 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E+ P GTTV+ V+A D+D IN +++Y+L E S++ F I+ QTG ITT K Sbjct: 2794 ENLPSGTTVIQVTANDADANINGEVSYTLEPE-SDDI----GDMFAIDSQTGWITTLKEA 2848 Query: 540 DRETMSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 D ET + V A D G S + VE+++ D NDN P F ++LY +I+E++ G Sbjct: 2849 DSETKQLHRFFVVATDHGDALKQSASVLVEVTLTDENDNPPQFTEELYQGSILENSRPGE 2908 Query: 599 SVSQVGATDADVGLNGR--IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 ++ + D DV R + Y D + S + + LDRE + LK Sbjct: 2909 NIVTLTTADKDVSAENRQIVCYITDGDPLGQFSVTAVGEEWTVISKSPLDREDKDKYTLK 2968 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 +A DG S+ V VH+ D+ND+ P E T + ENS G I +I A DPD Sbjct: 2969 IIATDGRF-QTSANVEVHVL--DLNDNSPFCEQLQYTEAVMENSSSGKVILKISASDPDI 3025 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN 776 G N V +++ G +++ F L+ + G EL T+ LD E K+Y+LV++A + Sbjct: 3026 GTNGQVSFTLH-GPNADKFHLDPKTG----ELFTLAVLDRER-EKEYDLVVKATDGGGRS 3079 Query: 777 -DVRVEILVTDVNDNAPVM--KDFQI-IFNNYKDCFPVGP-FGRVPAYDADVTDKLQYRI 831 V ++V D+NDN P +++ +F+N P+ + + P D + +++Y Sbjct: 3080 CQADVTLMVQDMNDNPPQFSTSHYEVTVFDNTTIRTPIAVIYAKDP--DTGINSEVRYS- 3136 Query: 832 LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 L G ++ L+E +G + L L M+V TD Sbjct: 3137 LQGADSGFFSLDEISGVLRLERSLADETKSTYEMKVKATD 3176 Score = 278 bits (682), Expect = 1e-72 Identities = 252/880 (28%), Positives = 394/880 (44%), Gaps = 74/880 (8%) Query: 17 NDHSPVFEMQQYEA-SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDA 75 N HSP F + + +RE + +VL ATD D G N ++ Y+I D Sbjct: 700 NQHSPKFVISTPGSIDIREDFALNRSVLQFNATDNDSGFNGKLVYSISSGNED------- 752 Query: 76 XXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTAT 135 F ID +G L +LDRE+ Y + + D P + S+ Sbjct: 753 ------------GCFTIDVNAGDLKVICALDREQKEFYILNITVYDLGYP---QTSTWKL 797 Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195 + VNI+D NDN P FS+ Y V++ E+ V + I K+ A D D+ N A +Y++ Sbjct: 798 LAVNILDANDNPPLFSQSRYVVTIPENTEVDKS--IFKVNAVDFDLDNNGAFKYSLF-TF 854 Query: 196 TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS--NTTQLLINIRDVNDN 253 T + F I+ +G V ++ LD E R Y L I A+D P + T +++ + D+NDN Sbjct: 855 TDL-FQIEEDTGVVKVIGPLDRETFRRYDLTIEARDQAKPDPQLFSFTDVVVVLEDINDN 913 Query: 254 APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313 P+F ++++ V E+VP G ++ V+++D D ++Y + + + +G +D Sbjct: 914 PPKFVPTVYKIKVPEDVPPGTVLLWVESFDLDLESGGVISYNLKNSE-SGT----FFLDT 968 Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP--GQ- 370 +G + +LD E + Y L V A D G PRS +++ P G+ Sbjct: 969 STGSLTLERELDFEKRQFYNLTVRAVDHG-KPRSLSSSCFIEIEVLDVNENLNRPLFGEM 1027 Query: 371 -YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 + + ED GT V+TLTA D D D + Y I G+ G F++ + G+I A Sbjct: 1028 VHTAAVMEDAKIGTSVLTLTAVDNDLGRDGVVRYYIHDGSGLGVFTVDEET--GVIQTAG 1085 Query: 428 PLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 LD + Y LTV A D G V I + D N+ P Y SV E+ P Sbjct: 1086 LLDREVVPHYWLTVYAKDLGTIPLVSWTEVYIEVWDINDNPPELSQPVYFGSVQENLPKD 1145 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 +VL VSATD D ++ + + + ++ + F I+ +TG I+T LDRE + Sbjct: 1146 KSVLKVSATDMDKSSEGKLAFQI---LDSQRI-----YFTIDSKTGVISTLSSLDREQKA 1197 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME--DALVGTSVSQV 603 +++ V D G P LS T V I V+D NDN P F +L+ + E + ++ Sbjct: 1198 EHIIEVMVSDKGEPPLSSTATVVIEVLDENDNSPQFSHKLFQIKLPERQSTAEPQDIYRM 1257 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 A D DVG NG I Y L+ D EG F I P +GV+ R + + L A D G Sbjct: 1258 VARDDDVGPNGMITYSLE--DNNEGRFDIHPDTGVVTARGQFVRGNYSI--LTIQATDQG 1313 Query: 664 TPPQSSTVIVHIK-IEDINDSPPV--FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 PP+ S +H++ + S V F+ + + E P+ +G IR E P Sbjct: 1314 NPPRMSKSRLHVEWLPQPEPSSDVLAFDEPPFNYVVMETDPVTDMVGIIRT----EIPKN 1369 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRV 780 ++ + I GGD+ F +E GS +V L+ + Y L +R + Sbjct: 1370 LLLFDIIGGDEEQDFYIEKNTGS----IVKARRLN-AGKKSHYNLTVRVTDGFQTITTQA 1424 Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLI 840 I V D+N++ P+ +D P + A+DAD + L Y I S N + Sbjct: 1425 YIQVVDINEHRPMFLKSLYEVRVPEDTSPWKEILHISAHDADASSGLFYSIHSSLNPESL 1484 Query: 841 L---LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIK 877 L++ +G + L +L+ T+ V V D IK Sbjct: 1485 KYFHLDQRSGVLVLKEELDYETISTHTLIVMVRDDKIPIK 1524 Score = 264 bits (647), Expect = 2e-68 Identities = 223/787 (28%), Positives = 368/787 (46%), Gaps = 47/787 (5%) Query: 133 TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192 T + +NI + + +F ++ + +V E+ T ++ ++AT + N +++ ++ Sbjct: 1941 TTVVKLNITNATKSSLKFEDRAHVATVLENS--TSVKILVVLRATGTYL--NEPLQFTVL 1996 Query: 193 GGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251 N +F++ SG + D E+ Y + + +D SP R + T + + I DVN Sbjct: 1997 --NPHGKFAVIPSSGVLHTTGVPFDREEQDVYDVAVEVRDFRSPPRVDVTHVKVYIDDVN 2054 Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311 DN P +S+ G + +V A D D G N + +++ D +DL + Sbjct: 2055 DNVPEILNLPKTLLISDETEPGDVLFQVLATDNDFGENGSIIFSLEDDFGLFRIDLYL-- 2112 Query: 312 DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371 G V LD E+ KY L V +D G P SA T F Y Sbjct: 2113 ----GDVSLQRPLDFESMNKYVLTVLVSDDGQPSLSAIGTIYIQVQNRSHPI--FQSMYY 2166 Query: 372 EVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431 ++L E+ P T ++ + A + E RL Y + N F+I + G +++V LDF Sbjct: 2167 PLKLPENITPFTTILHVQARNP-EGYRLIYNLEEDNASRLFNIDFKTG--VLSVTDFLDF 2223 Query: 432 KQERRYVLTVSATDS-GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 + E +++LTV ATDS G A V+I++ D N+ APVF+N Y A VFE PIGT+VL Sbjct: 2224 ESETKHILTVRATDSVSGTFAEAKVEIDVEDINDNAPVFQNLSYVADVFEGLPIGTSVLQ 2283 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550 VSA D D NA+ TY L I E+ H F I+P +G + T ++LD E+ + L Sbjct: 2284 VSAVDRDADKNAEATYQL---IDKES--HF---FEIDPLSGVLVTTQVLDYESTQQFTLK 2335 Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610 V A D GVP LS + ++V+DVNDN P F + Y A++ E A G V +V A+D D Sbjct: 2336 VKATDKGVPPLSGEAHIIVNVIDVNDNPPDFSEPSYRASLDEMATCGNIVIKVQASDPD- 2394 Query: 611 GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST 670 + Y++ E F I+ +SG+I + R ++L DG T Sbjct: 2395 -SKDDLQYKI-LSGNEGRYFAINESSGLISFSNVCKRNLDPFYNLTVAVSDG---VFQKT 2449 Query: 671 VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD 730 V+I + + N P F + ++EN+ +GT + + A DPD+GP V Y+I Sbjct: 2450 APVNIDMTNGNKYSPYFTQNIYEADLAENAEVGTRVIRLAAIDPDDGPYGSVDYTIINKL 2509 Query: 731 DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDV---RVEILVTDV 787 F++ ++ ++VT LD E+P ++ + I+ + V V+I++TD Sbjct: 2510 ADEKFAI-----NEDGQIVTSQPLDRENPSQRV-IAIKIMAKDGGGRVGFCTVKIILTDE 2563 Query: 788 NDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNA--NLILLN 843 NDN P K + + P ++ AYDAD + Y + + ++I +N Sbjct: 2564 NDNVPQFKASEYDISIQSTVNKGSPVIQIMAYDADEGKNADVTYTVEEADEVTEDIIEVN 2623 Query: 844 ETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEEMLLNSITVRLND 902 TG +++ L K+ +V D G + + + V+++ E++L T L Sbjct: 2624 PFTGVVSVKESLVGLENKIFNFKVKARDGGFPFYNSSVPVQVKVVPPEIILPRFTEPLYS 2683 Query: 903 MTAEQFL 909 +A + L Sbjct: 2684 FSASEDL 2690 Score = 264 bits (646), Expect = 3e-68 Identities = 228/869 (26%), Positives = 381/869 (43%), Gaps = 65/869 (7%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 D ND+ P F Y+ V E GT +L +++ D D+ + Y ++ N E Sbjct: 909 DINDNPPKFVPTVYKIKVPEDVPPGTVLLWVESFDLDLESGGVISYNLK-------NSES 961 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134 F +D +G+L LD EK Y + V+A D P S LSS+ Sbjct: 962 GT-------------FFLDTSTGSLTLERELDFEKRQFYNLTVRAVDHGKPRS--LSSSC 1006 Query: 135 TIHVNIIDDNDNY--PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192 I + ++D N+N P F E +T +V ED + + + + A D D+G + +RY I Sbjct: 1007 FIEIEVLDVNENLNRPLFGEMVHTAAVMEDAKIGTS--VLTLTAVDNDLGRDGVVRYYIH 1064 Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252 G+ F++D +G + LD E V Y L + A+D G+ + T++ I + D+ND Sbjct: 1065 DGSGLGVFTVDEETGVIQTAGLLDREVVPHYWLTVYAKDLGTIPLVSWTEVYIEVWDIND 1124 Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312 N P ++ SV EN+P S+++V A D D+ +L + + D + TID Sbjct: 1125 NPPELSQPVYFGSVQENLPKDKSVLKVSATDMDKSSEGKLAFQILDSQ-----RIYFTID 1179 Query: 313 PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE 372 ++G + T LDRE +A++ + V +D G+PP S+TAT F ++ Sbjct: 1180 SKTGVISTLSSLDREQKAEHIIEVMVSDKGEPPLSSTATVVIEVLDENDNSPQFSHKLFQ 1239 Query: 373 VELAEDEPPGTP--VVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 ++L E + P + + A D D + + Y + N GRF I G V Sbjct: 1240 IKLPERQSTAEPQDIYRMVARDDDVGPNGMITYSLE-DNNEGRFDIHPDTG----VVTAR 1294 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 F + +LT+ ATD G + ++++ + P E + F++ P V Sbjct: 1295 GQFVRGNYSILTIQATDQGNPPRMSKSRLHV----EWLPQPEPSS-DVLAFDEPPFNYVV 1349 Query: 489 LVVSATDSDVG-INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 + VG I +I +L + + +Q F I TG+I + L+ S Y Sbjct: 1350 METDPVTDMVGIIRTEIPKNLL--LFDIIGGDEEQDFYIEKNTGSIVKARRLNAGKKSHY 1407 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 LTV DG + TT I VVD+N++ P+F + LY + ED + + A D Sbjct: 1408 NLTVRVTDG---FQTITTQAYIQVVDINEHRPMFLKSLYEVRVPEDTSPWKEILHISAHD 1464 Query: 608 ADV--GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 AD GL IH L+P+ + F +D SGV+ + LD E+++TH L + D P Sbjct: 1465 ADASSGLFYSIHSSLNPESLK--YFHLDQRSGVLVLKEELDYETISTHTLIVMVRDDKIP 1522 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 + + V + +ED ND P F IS + GT + ++A D D G NA + YS Sbjct: 1523 IKKNFAKVVVHVEDCNDHIPSFLDTHYEGIISNLALTGTEVLRVKALDKDTGSNADIVYS 1582 Query: 726 I-KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP--PLWNDVRVEI 782 GG+ +F ++ GS + + D P++ Y L ++A P + + Sbjct: 1583 FHSGGNVDGAFKIDQGTGS-----IRVSDALDRLPQEHYHLTVKATDQGFPQRSALCPVT 1637 Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILL 842 + +++ P + + P P V + A + YRI G+ + Sbjct: 1638 ITIKLSEFTPPRFSSKEYITEISEAMP--PGSPVLSVSARCPSSVLYRINEGDPNGTFHI 1695 Query: 843 NETTGSMTLSPQLNTNVPKLATMEVSVTD 871 N +G +++ L+ +++S T+ Sbjct: 1696 NINSGLLSVKNALDFEQHSSYHLQISATN 1724 Score = 263 bits (645), Expect = 4e-68 Identities = 211/718 (29%), Positives = 334/718 (46%), Gaps = 58/718 (8%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F I+ +G+++ L+ K + Y + V+ TD + T ++ ++D N++ P Sbjct: 1384 FYIEKNTGSIVKARRLNAGKKSHYNLTVRVTDGFQTI------TTQAYIQVVDINEHRPM 1437 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI---IGGNTQMQFSIDSLS 206 F + Y V V ED S I I A DAD A+S + Y+I + + F +D S Sbjct: 1438 FLKSLYEVRVPEDTSPWKE--ILHISAHDAD--ASSGLFYSIHSSLNPESLKYFHLDQRS 1493 Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266 G + L + LDYE + ++ L++ +D P + N ++++++ D ND+ P F + ++ + Sbjct: 1494 GVLVLKEELDYETISTHTLIVMVRDDKIPIKKNFAKVVVHVEDCNDHIPSFLDTHYEGII 1553 Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326 S G ++RV+A D D G NA++ Y+ GNVD ID +G + S LDR Sbjct: 1554 SNLALTGTEVLRVKALDKDTGSNADIVYSFHSG---GNVDGAFKIDQGTGSIRVSDALDR 1610 Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386 Q Y L V ATD G P RSA F +Y E++E PPG+PV+ Sbjct: 1611 LPQEHYHLTVKATDQGFPQRSALCPVTITIKLSEFTPPRFSSKEYITEISEAMPPGSPVL 1670 Query: 387 TLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446 +++A + Y I G+ G F I +G L++V LDF+Q Y L +SAT++ Sbjct: 1671 SVSARCPSS---VLYRINEGDPNGTFHININSG--LLSVKNALDFEQHSSYHLQISATNT 1725 Query: 447 GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT-------TVLVVSATDSDVG 499 G S A+V + + DAN+ APVF Y + E AP+ + T LV+ A+D+D Sbjct: 1726 AGISSDAVVFVYVIDANDNAPVFHQDVYYGQISESAPVNSMVTGENNTPLVIKASDADKD 1785 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 NA + Y + E AH + F I+P G I+ L+D E + +V D G P Sbjct: 1786 TNALLVYQIL-----EPAAH--EVFKIDPSMGTISLKSLIDFEATPEFFFSVQVWDSGEP 1838 Query: 560 SLSDT--TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617 SLS + V I V+D ND P F +Y + V QV A DAD + I Sbjct: 1839 SLSASKPCKVIIRVLDFNDCPPKFVLPVYEIALTWPVFQDMKVIQVTAHDADSAVTYMI- 1897 Query: 618 YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 ++ + +F ID ++GVI N + + +S ++LK A DG T +V + I Sbjct: 1898 ----LENSNKNAFKIDQSTGVISVNDSSELQS--HNELKITAFDG---LYKDTTVVKLNI 1948 Query: 678 EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL 737 + S FE + ENS + +RA N + +++ + F++ Sbjct: 1949 TNATKSSLKFEDRAHVATVLENSTSVKILVVLRA--TGTYLNEPLQFTVL--NPHGKFAV 2004 Query: 738 ETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792 G T V D E + Y++ + SPP + V++ + DVNDN P Sbjct: 2005 IPSSG---VLHTTGVPFDREE-QDVYDVAVEVRDFRSPPRVDVTHVKVYIDDVNDNVP 2058 Score = 240 bits (587), Expect = 5e-61 Identities = 242/901 (26%), Positives = 404/901 (44%), Gaps = 80/901 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+ P Y SV+E +VL + ATD D K++E + +++ + + Sbjct: 1117 IEVWDINDNPPELSQPVYFGSVQENLPKDKSVLKVSATDMD--KSSEGKLAFQILDSQRI 1174 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F ID ++G + T +SLDRE+ A + + V +D+ P L Sbjct: 1175 ------------------YFTIDSKTGVISTLSSLDREQKAEHIIEVMVSDKGEPP---L 1213 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SSTAT+ + ++D+NDN PQFS K + + + E S + I ++ A D DVG N I Y+ Sbjct: 1214 SSTATVVIEVLDENDNSPQFSHKLFQIKLPERQSTAEPQDIYRMVARDDDVGPNGMITYS 1273 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVR-SYR-LVIRAQDGGSPSRSNTTQLLINIR 248 + N + +F I +G V T + VR +Y L I+A D G+P R + ++L ++ Sbjct: 1274 L-EDNNEGRFDIHPDTG----VVTARGQFVRGNYSILTIQATDQGNPPRMSKSRL--HVE 1326 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV-NAELTYTMTDKDYTG-NVD 306 + P F E P Y ++ G+ E+ + D G + + Sbjct: 1327 WLPQPEPSSDVLAFDEP-----PFNYVVMETDPVTDMVGIIRTEIPKNLLLFDIIGGDEE 1381 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 I+ +G + + +L+ ++ Y L V TDG ++ T F Sbjct: 1382 QDFYIEKNTGSIVKARRLNAGKKSHYNLTVRVTDGF---QTITTQAYIQVVDINEHRPMF 1438 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG-NTRGRFSITSQNGRGLITV 425 + YEV + ED P ++ ++A DAD + L Y I N G++ + Sbjct: 1439 LKSLYEVRVPEDTSPWKEILHISAHDADASSGLFYSIHSSLNPESLKYFHLDQRSGVLVL 1498 Query: 426 AQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 + LD++ + L V D + + A V +++ D N++ P F + Y + A Sbjct: 1499 KEELDYETISTHTLIVMVRDDKIPIKKNFAKVVVHVEDCNDHIPSFLDTHYEGIISNLAL 1558 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 GT VL V A D D G NA I YS S + D F I+ TG+I + LDR Sbjct: 1559 TGTEVLRVKALDKDTGSNADIVYSFHSG------GNVDGAFKIDQGTGSIRVSDALDRLP 1612 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 Y LTV A D G P S V I++ P F + Y I E G+ V V Sbjct: 1613 QEHYHLTVKATDQGFPQRSALCPVTITIKLSEFTPPRFSSKEYITEISEAMPPGSPVLSV 1672 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 A L RI+ E DP G+F I+ SG++ ALD E +++ L+ A + Sbjct: 1673 SARCPSSVLY-RIN-EGDPN----GTFHININSGLLSVKNALDFEQHSSYHLQISATN-- 1724 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI-GE------IRAHDPDE 716 T SS +V + + D ND+ PVF D ISE++P+ + + GE I+A D D+ Sbjct: 1725 TAGISSDAVVFVYVIDANDNAPVFHQDVYYGQISESAPVNSMVTGENNTPLVIKASDADK 1784 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN 776 NA++ Y I F ++ G+ L +++D + +P + + + + P + Sbjct: 1785 DTNALLVYQILEPAAHEVFKIDPSMGT--ISLKSLIDFE-ATPEFFFSVQVWDSGEPSLS 1841 Query: 777 ---DVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRI 831 +V I V D ND P V+ ++I F +V A+DAD + Y I Sbjct: 1842 ASKPCKVIIRVLDFNDCPPKFVLPVYEIALT--WPVFQDMKVIQVTAHDAD--SAVTYMI 1897 Query: 832 LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEM 891 L +N N ++++TG ++++ ++ + ++++ DG+ + +++L++ T+ Sbjct: 1898 LENSNKNAFKIDQSTGVISVND--SSELQSHNELKITAFDGLYKDTTVVKLNITNATKSS 1955 Query: 892 L 892 L Sbjct: 1956 L 1956 Score = 228 bits (557), Expect = 2e-57 Identities = 240/903 (26%), Positives = 403/903 (44%), Gaps = 81/903 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +N+LD ND+ P+F +Y ++ E ++ + A D D+ N +Y++ T Sbjct: 800 VNILDANDNPPLFSQSRYVVTIPENTEVDKSIFKVNAVDFDLDNNGAFKYSLFTFT---- 855 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 D+F+I+ +G + LDRE RY + ++A DQA P +L Sbjct: 856 -----------------DLFQIEEDTGVVKVIGPLDRETFRRYDLTIEARDQAKP-DPQL 897 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S + V + D NDN P+F Y + V ED V V+ +++ D D+ + I Y Sbjct: 898 FSFTDVVVVLEDINDNPPKFVPTVYKIKVPED--VPPGTVLLWVESFDLDLESGGVISYN 955 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP-SRSNTTQLLINIRD 249 + + F +D+ +G ++L + LD+E+ + Y L +RA D G P S S++ + I + D Sbjct: 956 LKNSESG-TFFLDTSTGSLTLERELDFEKRQFYNLTVRAVDHGKPRSLSSSCFIEIEVLD 1014 Query: 250 VND--NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 VN+ N P F + +V E+ IG S++ + A D D G + + Y + D G Sbjct: 1015 VNENLNRPLFGEMVHTAAVMEDAKIGTSVLTLTAVDNDLGRDGVVRYYIHDGSGLG---- 1070 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 T+D +G + T+G LDRE Y L V A D G P + Sbjct: 1071 VFTVDEETGVIQTAGLLDREVVPHYWLTVYAKDLGTIPLVSWTEVYIEVWDINDNPPELS 1130 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITV 425 Y + E+ P V+ ++ATD D+ + +L ++I + R F+I S+ G+I+ Sbjct: 1131 QPVYFGSVQENLPKDKSVLKVSATDMDKSSEGKLAFQIL-DSQRIYFTIDSKT--GVIST 1187 Query: 426 AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 LD +Q+ +++ V +D G S TA V I + D N+ +P F + + + E Sbjct: 1188 LSSLDREQKAEHIIEVMVSDKGEPPLSSTATVVIEVLDENDNSPQFSHKLFQIKLPERQS 1247 Query: 484 IG--TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 + + A D DVG N ITYSL E +NE +F I+P TG +T R Sbjct: 1248 TAEPQDIYRMVARDDDVGPNGMITYSL--EDNNEG------RFDIHPDTGVVTARGQFVR 1299 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVV---DVNDNEPVFKQQLYTANIMEDALVGT 598 S +LT+ A D G P + + + + + + + F + + +ME V Sbjct: 1300 GNYS--ILTIQATDQGNPPRMSKSRLHVEWLPQPEPSSDVLAFDEPPFNYVVMETDPV-- 1355 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 VG ++ N + +++ D EE F I+ +G I + L+ + ++L Sbjct: 1356 -TDMVGIIRTEIPKN-LLLFDIIGGD-EEQDFYIEKNTGSIVKARRLNAGKKSHYNLTVR 1412 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 DG Q+ T +I++ DIN+ P+F + E++ I I AHD D Sbjct: 1413 VTDGF---QTITTQAYIQVVDINEHRPMFLKSLYEVRVPEDTSPWKEILHISAHDAD--A 1467 Query: 719 NAVVHYSIKGGDDSNS---FSLETRQGSDKAELVTMVDLDYESPRKKYELV-IRAASPPL 774 ++ + YSI + S F L+ R G LV +LDYE+ +V +R P+ Sbjct: 1468 SSGLFYSIHSSLNPESLKYFHLDQRSG----VLVLKEELDYETISTHTLIVMVRDDKIPI 1523 Query: 775 -WNDVRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQY 829 N +V + V D ND+ P D ++ I +N RV A D D + Y Sbjct: 1524 KKNFAKVVVHVEDCNDHIPSFLDTHYEGIISNL--ALTGTEVLRVKALDKDTGSNADIVY 1581 Query: 830 RILSGNNAN-LILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLI 887 SG N + +++ TGS+ +S L+ + + V TD G + A+ +++ + Sbjct: 1582 SFHSGGNVDGAFKIDQGTGSIRVSDALDRLPQEHYHLTVKATDQGFPQRSALCPVTITIK 1641 Query: 888 TEE 890 E Sbjct: 1642 LSE 1644 Score = 202 bits (492), Expect = 1e-49 Identities = 225/884 (25%), Positives = 383/884 (43%), Gaps = 89/884 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V+D N+H P+F YE V E S +L + A D D ++ + Y+I +L Sbjct: 1426 IQVVDINEHRPMFLKSLYEVRVPEDTSPWKEILHISAHDAD--ASSGLFYSIH----SSL 1479 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 NPE F +D RSG L+ + LD E ++ +T++V D P+ Sbjct: 1480 NPESL------------KYFHLDQRSGVLVLKEELDYETISTHTLIVMVRDDKIPIK--- 1524 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + A + V++ D ND+ P F + T+ + ++++T V+ ++KA D D G+N+ I Y+ Sbjct: 1525 KNFAKVVVHVEDCNDHIPSFLD-THYEGIISNLALTGTEVL-RVKALDKDTGSNADIVYS 1582 Query: 191 I-IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 GGN F ID +G + + LD Y L ++A D G P RS + I I+ Sbjct: 1583 FHSGGNVDGAFKIDQGTGSIRVSDALDRLPQEHYHLTVKATDQGFPQRSALCPVTITIKL 1642 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 PRF + + +SE +P G ++ V A + + Y + + D G + I Sbjct: 1643 SEFTPPRFSSKEYITEISEAMPPGSPVLSVSA-----RCPSSVLYRINEGDPNGTFHINI 1697 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 SG + LD E + Y L ++AT+ S+ A F Sbjct: 1698 ----NSGLLSVKNALDFEQHSSYHLQISATNTAG--ISSDAVVFVYVIDANDNAPVFHQD 1751 Query: 370 QYEVELAEDEPPGTPV-------VTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGR 420 Y +++E P + V + + A+DAD+D L Y+I F I Sbjct: 1752 VYYGQISESAPVNSMVTGENNTPLVIKASDADKDTNALLVYQILEPAAHEVFKI--DPSM 1809 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNYAPVFENAPYTA 476 G I++ +DF+ + +V DSG S V I + D N+ P F Y Sbjct: 1810 GTISLKSLIDFEATPEFFFSVQVWDSGEPSLSASKPCKVIIRVLDFNDCPPKFVLPVYEI 1869 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 ++ V+ V+A D+D + +TY + E SN+ F I+ TG I+ N Sbjct: 1870 ALTWPVFQDMKVIQVTAHDAD----SAVTYMI-LENSNK------NAFKIDQSTGVISVN 1918 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 E S L +TA DG DTT V++++ + + F+ + + A ++E++ Sbjct: 1919 D--SSELQSHNELKITAFDG---LYKDTTVVKLNITNATKSSLKFEDRAHVATVLENSTS 1973 Query: 597 GTSVSQVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGVIRTNKA-LDRESVATHD 654 + + AT LN + + L+P G F + P+SGV+ T DRE +D Sbjct: 1974 VKILVVLRAT--GTYLNEPLQFTVLNP----HGKFAVIPSSGVLHTTGVPFDREEQDVYD 2027 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 + D +PP+ V + I+D+ND+ P + T IS+ + G + ++ A D Sbjct: 2028 VAVEVRDFRSPPRVDVTHVKVYIDDVNDNVPEILNLPKTLLISDETEPGDVLFQVLATDN 2087 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA--SP 772 D G N + +S++ DD F ++ G ++ LD+ES KY L + + Sbjct: 2088 DFGENGSIIFSLE--DDFGLFRIDLYLG----DVSLQRPLDFES-MNKYVLTVLVSDDGQ 2140 Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYR 830 P + + I + N + P+ FQ ++ K + PF + A + +L Y Sbjct: 2141 PSLSAIGT-IYIQVQNRSHPI---FQSMYYPLKLPENITPFTTILHVQARNPEGYRLIYN 2196 Query: 831 ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN 874 + N + L ++ TG ++++ L+ + V TD V+ Sbjct: 2197 LEEDNASRLFNIDFKTGVLSVTDFLDFESETKHILTVRATDSVS 2240 Score = 175 bits (427), Expect = 1e-41 Identities = 169/588 (28%), Positives = 274/588 (46%), Gaps = 48/588 (8%) Query: 103 ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162 A L+RE YT+ V+AT+ D + T + + ++D ND P F +Y V + ED Sbjct: 99 AVLNREVRDIYTLTVEATESTF---DNRARTKVL-IQVLDTNDLKPLFYPASYHVVIKED 154 Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222 + + + ++ ATDAD+G+N+ Y+ F++D +G V+LVK LD Q Sbjct: 155 TPIKSS--LVRVSATDADIGSNAEFYYSFT--TRSHPFAVDPFTGTVTLVKRLDTSQRDR 210 Query: 223 YRLVIRAQD-----GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSI- 276 Y L + A+D G N +++ I+ V N +T + + + I I Sbjct: 211 YDLTVLAEDRKKKISGVQKFGNVATVVVKIQKVEKN----FTLISPTTAESLLTIDDKIS 266 Query: 277 VRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD-RETQAKYQLL 335 V ++ ++ A L+ D + +P + ++ +D + + Sbjct: 267 VNIKMEPKEKENTASLSIVKGDPLNCFQI-IPSAFYDGGFQLVSTKFIDWSQNPLGLNIS 325 Query: 336 VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395 + A D +PP F Y V L+E PP T VV ++ + + Sbjct: 326 LQAKDRSNPPLLTPIKTVHIPPPLQIKPLRFEQELYYVTLSEFSPPKTHVVRVSVGLSLK 385 Query: 396 DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMV 455 + + I +F I+++ G +I +Q LDF+ Y V+A D G + T ++ Sbjct: 386 NTT--FSIQENPDSYKFKISAKTG--VIVTSQSLDFENRNHYEFDVTAND--GEAVTRVI 439 Query: 456 QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515 ++ITD N+ AP F Y AS+ E+ IGT+VL VSA D D N +TY+ I+N Sbjct: 440 -VDITDENDNAPSFTLPSYQASLPENVRIGTSVLSVSAIDVDKDNNGFVTYA----IANT 494 Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMS-GYLLTVTARDGGVP--SLSDTTDVEISVV 572 F I+P TG I+T++ D E M Y L + A D G P +S+ T V I++ Sbjct: 495 GPV----PFSIDPLTGVISTSQEFDYELMKRWYHLRIWASDSGNPFNRVSECT-VTITMT 549 Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632 +VNDN PVF++ A+I D VG ++++ A D D +I Y ++ ++G F I Sbjct: 550 NVNDNVPVFERVACNASIPRDFAVGEIIAEISALDLDE--LQQIVYRIE-SGNDDGLFSI 606 Query: 633 DPASGVIRTNKAL-----DRESVATHDLKAVAIDGGTPPQSSTVIVHI 675 DP SG+I+ KA+ D E+ + + LK A DG +TV V I Sbjct: 607 DPVSGIIKLAKAIPSNYKDTEN-SLYTLKITATDGTYIADPNTVTVSI 653 Score = 166 bits (404), Expect = 7e-39 Identities = 186/688 (27%), Positives = 295/688 (42%), Gaps = 61/688 (8%) Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L + H +++ D+ + +F+ Y S+ E+ S V + ++ I+Y Sbjct: 8 LGTLTRCHGSLVKDS-SLLRFTHHLYNASIYEN-SAPKTYVESSVRMGILLTDPFWNIKY 65 Query: 190 AIIGGNTQMQFSIDSLS-GDVSLVKTLDYE--------QVRS-YRLVIRAQDGGSPSRSN 239 I+ G+ F + GD S ++ + +VR Y L + A + +R+ Sbjct: 66 KIVSGDDDGLFQTEKEDVGDFSFLRIITRSSNSAVLNREVRDIYTLTVEATESTFDNRAR 125 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 T ++LI + D ND P FY + + + E+ PI S+VRV A DAD G NAE Y+ T + Sbjct: 126 T-KVLIQVLDTNDLKPLFYPASYHVVIKEDTPIKSSLVRVSATDADIGSNAEFYYSFTTR 184 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD-----GGDPPRSATATXXX 354 + P +DP +G V +LD + +Y L V A D G AT Sbjct: 185 SH------PFAVDPFTGTVTLVKRLDTSQRDRYDLTVLAEDRKKKISGVQKFGNVATVVV 238 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSI 414 P E L D+ V + +++N I G+ F I Sbjct: 239 KIQKVEKNFTLISPTTAESLLTIDDKIS---VNIKMEPKEKENTASLSIVKGDPLNCFQI 295 Query: 415 TSQ---NGRGLITVAQPLDFKQERRYV-LTVSATD-SGGRSDTAMVQINITDANNYAPV- 468 +G + + +D+ Q + +++ A D S T + ++I P+ Sbjct: 296 IPSAFYDGGFQLVSTKFIDWSQNPLGLNISLQAKDRSNPPLLTPIKTVHIPPPLQIKPLR 355 Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ-ITYSLSSEISNEAVAHHDQQFVIN 527 FE Y ++ E +P T V+ VS VG++ + T+S+ + +F I+ Sbjct: 356 FEQELYYVTLSEFSPPKTHVVRVS-----VGLSLKNTTFSIQENPDS-------YKFKIS 403 Query: 528 PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT 587 +TG I T++ LD E + Y VTA DG T V + + D NDN P F Y Sbjct: 404 AKTGVIVTSQSLDFENRNHYEFDVTANDG-----EAVTRVIVDITDENDNAPSFTLPSYQ 458 Query: 588 ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647 A++ E+ +GTSV V A D D NG + Y + + F IDP +GVI T++ D Sbjct: 459 ASLPENVRIGTSVLSVSAIDVDKDNNGFVTYAI--ANTGPVPFSIDPLTGVISTSQEFDY 516 Query: 648 ESVAT-HDLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 E + + L+ A D G P + S V I + ++ND+ PVFE I + +G Sbjct: 517 ELMKRWYHLRIWASDSGNPFNRVSECTVTITMTNVNDNVPVFERVACNASIPRDFAVGEI 576 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY-ESPRKKYE 764 I EI A D DE V Y I+ G+D FS++ G K L + +Y ++ Y Sbjct: 577 IAEISALDLDELQQIV--YRIESGNDDGLFSIDPVSGIIK--LAKAIPSNYKDTENSLYT 632 Query: 765 LVIRAASPPLWNDVR-VEILVTDVNDNA 791 L I A D V + +TD + A Sbjct: 633 LKITATDGTYIADPNTVTVSITDNGEGA 660 Score = 117 bits (281), Expect = 5e-24 Identities = 147/579 (25%), Positives = 241/579 (41%), Gaps = 69/579 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I VLD ND P+F Y ++E ++++ + ATD DIG NAE Y+ Sbjct: 130 IQVLDTNDLKPLFYPASYHVVIKEDTPIKSSLVRVSATDADIGSNAEFYYSF----TTRS 185 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS--D 128 +P F +D +G + LD + RY + V A D+ +S Sbjct: 186 HP-----------------FAVDPFTGTVTLVKRLDTSQRDRYDLTVLAEDRKKKISGVQ 228 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 + + AT+ V I N+ S T E + D+ + IK + +++ Sbjct: 229 KFGNVATVVVKIQKVEKNFTLISPTT-----AESLLTIDDKISVNIKMEPKEKENTASL- 282 Query: 189 YAIIGGNTQMQFSI---DSLSGDVSLVKT--LDYEQ-VRSYRLVIRAQDGGSPSRSNTTQ 242 +I+ G+ F I G LV T +D+ Q + ++A+D +P + Sbjct: 283 -SIVKGDPLNCFQIIPSAFYDGGFQLVSTKFIDWSQNPLGLNISLQAKDRSNPPLLTPIK 341 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 + + RF L+ ++SE P +VRV G++ + T T + ++ Sbjct: 342 TVHIPPPLQIKPLRFEQELYYVTLSEFSPPKTHVVRVSV-----GLSLKNT-TFSIQENP 395 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 + I+ ++G + TS LD E + Y+ VTA DG A Sbjct: 396 DSYKFKIS--AKTGVIVTSQSLDFENRNHYEFDVTANDG-----EAVTRVIVDITDENDN 448 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422 F Y+ L E+ GT V++++A D D+DN NT G + G+ Sbjct: 449 APSFTLPSYQASLPENVRIGTSVLSVSAIDVDKDNNGFVTYAIANT-GPVPFSIDPLTGV 507 Query: 423 ITVAQPLDFK-QERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASV 478 I+ +Q D++ +R Y L + A+DSG R V I +T+ N+ PVFE AS+ Sbjct: 508 ISTSQEFDYELMKRWYHLRIWASDSGNPFNRVSECTVTITMTNVNDNVPVFERVACNASI 567 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 D +G + +SA D D QI Y + S + D F I+P +G I K Sbjct: 568 PRDFAVGEIIAEISALDLDE--LQQIVYRIES-------GNDDGLFSIDPVSGIIKLAKA 618 Query: 539 LD---RETMSG-YLLTVTARDGGVPSLSDTTDVEISVVD 573 + ++T + Y L +TA DG ++D V +S+ D Sbjct: 619 IPSNYKDTENSLYTLKITATDG--TYIADPNTVTVSITD 655 Score = 112 bits (270), Expect = 1e-22 Identities = 152/594 (25%), Positives = 253/594 (42%), Gaps = 49/594 (8%) Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 T+K+ G+ + I RS S L+RE + Y L V AT+ R+ T Sbjct: 78 TEKEDVGDFSF-LRIITRSS---NSAVLNREVRDIYTLTVEATESTFDNRARTKVLIQVL 133 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITS 416 F P Y V + ED P + +V ++ATDAD + + + F++ Sbjct: 134 DTNDLKPL-FYPASYHVVIKEDTPIKSSLVRVSATDADIGSNAEFYYSFTTRSHPFAVDP 192 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA 476 G +T+ + LD Q RY LTV A D + + N A V Sbjct: 193 FTGT--VTLVKRLDTSQRDRYDLTVLAEDRKKKIS------GVQKFGNVATVVVKIQKVE 244 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ--FVINPQT---G 531 F TT + D + +N ++ ++ ++ D F I P G Sbjct: 245 KNFTLIS-PTTAESLLTIDDKISVNIKMEPKEKENTASLSIVKGDPLNCFQIIPSAFYDG 303 Query: 532 A--ITTNKLLD-RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV-FKQQLYT 587 + + K +D + G +++ A+D P L T + + +P+ F+Q+LY Sbjct: 304 GFQLVSTKFIDWSQNPLGLNISLQAKDRSNPPLL-TPIKTVHIPPPLQIKPLRFEQELYY 362 Query: 588 ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647 + E + T V +V VGL+ + ++ + F I +GVI T+++LD Sbjct: 363 VTLSEFSPPKTHVVRVS-----VGLSLKNTTFSIQENPDSYKFKISAKTGVIVTSQSLDF 417 Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 E+ ++ A DG ++ T ++ + I D ND+ P F + EN IGT++ Sbjct: 418 ENRNHYEFDVTANDG----EAVTRVI-VDITDENDNAPSFTLPSYQASLPENVRIGTSVL 472 Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 + A D D+ N V Y+I FS++ G + T + DYE ++ Y L I Sbjct: 473 SVSAIDVDKDNNGFVTYAI-ANTGPVPFSIDPLTG----VISTSQEFDYELMKRWYHLRI 527 Query: 768 RAA-SPPLWNDV---RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDAD 822 A+ S +N V V I +T+VNDN PV + + +D F VG + A D D Sbjct: 528 WASDSGNPFNRVSECTVTITMTNVNDNVPVFERVACNASIPRD-FAVGEIIAEISALDLD 586 Query: 823 VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVP----KLATMEVSVTDG 872 ++ YRI SGN+ L ++ +G + L+ + +N L T++++ TDG Sbjct: 587 ELQQIVYRIESGNDDGLFSIDPVSGIIKLAKAIPSNYKDTENSLYTLKITATDG 640 Score = 83.0 bits (196), Expect = 1e-13 Identities = 77/249 (30%), Positives = 118/249 (47%), Gaps = 33/249 (13%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +++ D ND++P F + Y+AS+ E GT+VL++ A D D N V Y I A+T Sbjct: 440 VDITDENDNAPSFTLPSYQASLPENVRIGTSVLSVSAIDVDKDNNGFVTYAI----ANT- 494 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSDR 129 P F ID +G + T D E + R Y + + A+D +P +R Sbjct: 495 GPVP---------------FSIDPLTGVISTSQEFDYELMKRWYHLRIWASDSGNPF-NR 538 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 +S T+ + + + NDN P F S+ D +V + +IA+I A D D I Y Sbjct: 539 VSE-CTVTITMTNVNDNVPVFERVACNASIPRDFAVGE--IIAEISALDLD--ELQQIVY 593 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTL--DYEQVRS--YRLVIRAQDGGSPSRSNTTQLLI 245 I GN FSID +SG + L K + +Y+ + Y L I A DG + NT + + Sbjct: 594 RIESGNDDGLFSIDPVSGIIKLAKAIPSNYKDTENSLYTLKITATDGTYIADPNT--VTV 651 Query: 246 NIRDVNDNA 254 +I D + A Sbjct: 652 SITDNGEGA 660 >UniRef50_UPI0000F200F1 Cluster: PREDICTED: similar to Fat4; n=3; Danio rerio|Rep: PREDICTED: similar to Fat4 - Danio rerio Length = 2870 Score = 369 bits (909), Expect = e-100 Identities = 386/1494 (25%), Positives = 645/1494 (43%), Gaps = 168/1494 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I++ D ND++P+F Y ++ E +L + ATD+D+G+NA+V Y I Sbjct: 1003 IDITDVNDNAPIFSQPVYSVTIPEMKMHEVFILQVSATDRDLGENAQVLYFI-------- 1054 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR--YTVLVKATDQASPVSD 128 NP + ++F ++ +G + + ++ ++ +T +V A+D + VS Sbjct: 1055 NPPN-------------ELFFVNASTGEISNKQTIALAELESEIFTFMVVASDCGN-VS- 1099 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSAI 187 L+S++ + V ++ N P F VS+ + V + ++ A D D + N+++ Sbjct: 1100 -LNSSSIVSVALVQYNYFPPMFLPFKPLVSIPLTLDVGSE--VIQVSAVDQDYLQMNNSV 1156 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 Y GGN + F ++ SG V + TL L I A+D G P + T++ + Sbjct: 1157 EYFNSGGNGSLYFQVEQNSGRVLVNATLANSLNMILTLEITAKDKGLPPIAAQTEISFEV 1216 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 N AP+F S + V E++P+G I ++Q D D G N ++Y+ GN + Sbjct: 1217 IQENQFAPQFLNSQVEFFVPEDLPVGSVIGKIQGKDKDVGSNGVISYSFDG----GNENG 1272 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 +I+ SG + LD E + L V A DGG P+ F Sbjct: 1273 LFSIEHFSGLIMLVKGLDFEKSETHHLSVIAKDGGWRPKKGRLNVTVYVTDLNDNPPIFT 1332 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITV 425 Y + E+ GT V+ + A D+D +++ Y + G+ + FS+ S+NG IT Sbjct: 1333 SKDYVASVLENAFIGTLVLQVWAKDSDTGIHSQITYSVIAGDAQ-LFSLDSKNGS--ITT 1389 Query: 426 AQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 + D++Q + + LTV AT+ G D A + I + N + P F+ Y SV E Sbjct: 1390 LEIFDYEQNQHFELTVKATNIGPPFLFDIARIYIQVVGVNEFIPAFQRHLYNFSVSEALM 1449 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 T + + ATD D+G + ++ Y L + FV++ TG I K L Sbjct: 1450 PQTEIGSILATDYDLGPDGEVFYILVGQSKKS-------NFVVDKHTGKIYIAKDLKTRL 1502 Query: 544 MSGYLLTVTARD-GGVPSLS-DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 + +L V A++ G + + D + +S++D ND P F LY + ED +GTS++ Sbjct: 1503 KNEDVLHVLAKNRGAITGFNVDEALIHLSILDEND-PPEFDSMLYIVAVSEDISIGTSIA 1561 Query: 602 QVGATDADVGLN-GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 +V A D DV L R Y ++ SF+IDP SGVI N LDRE A ++L +A+ Sbjct: 1562 KVKAVDPDVILEWSRFSYSIE-HGNINSSFIIDPVSGVISVNSHLDREIWAIYNLTVIAV 1620 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 D G+P + + V I + DINDSPP + +I EN P T + + A D D PN Sbjct: 1621 DEGSPSVTGSTKVAITVNDINDSPPKLLTT--EGFIRENQPADTLVSTLTATDDDLPPNQ 1678 Query: 721 --VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPRKKYELVIR-AASPPLWN 776 ++ ++ + FSL T + LVT D E P +V++ A PP+ + Sbjct: 1679 GPFTYWMMRPAE---GFSLTT-----EGVLVTSKPFDREHDPLFHMHIVVQDAGKPPMSS 1730 Query: 777 DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNN 836 I V D NDNAPV ++ I+ Y FP G G V D D D I +G Sbjct: 1731 TTLFHIKVLDENDNAPVPRNINILVKYYGSSFPGGLIGNVRPTDLDELDVFNCTIRNG-Q 1789 Query: 837 ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN-EIKAMMQLSVRLITEEMLLNS 895 + ++ SP ++ V +D ++ + + ++ + T L N Sbjct: 1790 PRMFSFPFGMCNLWSSPYQGEATYNIS---VEASDQLHPSVNNSIYVNYKGFTNVSLDNC 1846 Query: 896 ITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNV-SFSAR 954 + ++ T E+FLS F+ L ++ ++F ++ D + V S++ + Sbjct: 1847 VLFYVSISTLEEFLSLKYLKFVKALDSLFNLQASKTHVFGMKLQGDKMLLLAAVKSYNGQ 1906 Query: 955 RPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECL 1014 EV +G S +H+ L + V + N C+ PC N C Sbjct: 1907 YLTGEV-ASGISS-------------MHKKLLEAQSNVTISQITSNPCMLRPCHNGATCN 1952 Query: 1015 TVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETIL---TKASCEVDGD-- 1069 + + S S++F Y + F C CP GFTG CE K CE G+ Sbjct: 1953 RNIHISQEVAVLESSSLIFVSPYFMEIFNCTCPTGFTGDACELDFDECAKEPCENGGNCY 2012 Query: 1070 ---GS-ICR-----SGSQCVA-----------------RREGGILCQGCSIDAAYTTAV- 1102 G+ C+ SG C R+GG +C CS + V Sbjct: 2013 NNPGTYFCQCKEGFSGPHCTIVDNECQTVVCLNGGTCWNRQGGFICD-CSPGYEGVSGVN 2071 Query: 1103 CELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSS 1162 C+ ++ F S++ +P L ++ + L+FAT + LLLYN DFLALE++S Sbjct: 2072 CDEQSYGFQELSYIEYPPLDPQYNF-IYLEFATVQQNALLLYNHGKPSTSDFLALEILS- 2129 Query: 1163 EAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKVLSLA 1222 GR L S+ LG G + + DG +H + + ++ +D+C S+ Sbjct: 2130 --GR-----LFLSYDLGSGVIRLETGKIIADGLFHNISM------ASLEIDNC----SVY 2172 Query: 1223 GAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSF--QVKNKD 1280 F A ++ L E+ + + GG+ +I + Q++ D Sbjct: 2173 EPQGFCTTQTGATGNQRTL----EVSSNN----------MTFGGVKSIDAILLRQIRTHD 2218 Query: 1281 FVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKR-SRCSSAPCYNGAECSDLWDTYICDC 1339 FVGC+ + +++ D +A + L CP C +A C N C D W + C C Sbjct: 2219 FVGCMRNLQVNNIRPDSLKSLASHNILPRCPRTDIPPCEAAVCLNEGVCQDQWSHHRCQC 2278 Query: 1340 KEGHTGKDCADSTGPP--WRFGGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVM-SIQ 1396 ++ TG CA + G+ + F+ + L A+ ++ D+ S++ Sbjct: 2279 RDHFTGPSCAMNLAEQHVLFLNGEAYVKFDVKESYRRNQLLQAILDSGKEGDSLGFDSVE 2338 Query: 1397 LK-----SGLLHYSY----NGETMYLPM-ATLSDGAWHRIEIKWLGTDISVTVD 1440 +K G Y + +G + L + +SDG WH + ++ G+ S+ +D Sbjct: 2339 IKMRTISDGKPLYMFTNVTSGHQLELSVEGNVSDGQWHVLHLRRRGSLFSLFLD 2392 Score = 331 bits (814), Expect = 1e-88 Identities = 257/846 (30%), Positives = 403/846 (47%), Gaps = 69/846 (8%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72 V D NDH+P F Y SV E A GT +L + A+D+DIG N V ++I Sbjct: 287 VEDVNDHNPEFTQSIYSLSVYEDAPRGTILLKVGASDRDIGPNGLVRFSIS--------- 337 Query: 73 EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132 + F +D G +L +DREK Y+ V A DQ + S+ Sbjct: 338 --------------ESGFMVDSVLGIVLVIEKMDREKTPFYSFSVFAVDQGDV---QRST 380 Query: 133 TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192 TATI++ ++D ND P F ++ + V E+ + +I A+D D+GAN + Y+I Sbjct: 381 TATINITVLDVNDCVPNFLPESLIIHVLEN-GEDSSQHTHQIHASDEDLGANGQLTYSIE 439 Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252 GN + FS+ S +G + +++ LD E Y L + A D G PS + T L+I + D+ND Sbjct: 440 SGNDENLFSLHS-NGTIQILEDLDREVKSQYVLKVIAVDSGFPSLTGTGTLIIVVDDIND 498 Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312 N P F +F V E+ P+G S +R+ A D D+G +L Y++ +D P I+ Sbjct: 499 NIPVFEKDIFTAHVLEDSPVGTSFLRITASDLDDGTIGQLRYSLE------GLDFPFFIN 552 Query: 313 PRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSATATXXXXXXXXXXXXXXFMPGQY 371 SG ++T LDRET Y+ LV +DG P S++A F+ G Y Sbjct: 553 ATSGDLFTVSALDRETVPFYRFLVIVSDGHPTMPLSSSAAVVVTIEDVNDNFPSFLYGPY 612 Query: 372 EVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 + G+ V T+ A DAD + +L++ + G + FSI S G + ++ + Sbjct: 613 VANIPFGLTKGSVVCTVMAEDADVELNAKLNFSLQGQHAH-LFSINSHT--GTVLISDSI 669 Query: 430 DFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 + + + + V + DT + + + ++Y P Y S+FEDAPIGT V Sbjct: 670 NRRNDITIDVHVQDGAEMPKMDTTTLTVRFWN-DSYFPKIAVQVYKNSLFEDAPIGTLVA 728 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 +V+A + N + + L S + + F ++P TG +T LD ET + L Sbjct: 729 IVTA---ETLKNVSVYFYLPS-------GNFGEVFELHPSTGELTIKDPLDFETNMYFHL 778 Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 V ARD G+P S ++ +++ DVNDN PVF Q +Y + E+ L + V V A DAD Sbjct: 779 IVEARDSGIPPFSSYAELHLNISDVNDNPPVFSQDIYKCQVYEN-LASSRVCNVLAKDAD 837 Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669 G+ + Y + E +F ID G + T K LDRE + ++L AID + Sbjct: 838 SGVFAEVLYFI-LGGNIESTFKIDKNRGTLSTTKRLDREQIPYYNLSIKAIDKENNSLLA 896 Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729 + +++ D ND P F +T + EN+PIG ++ +I A D D G NAV+ Y+I G Sbjct: 897 VASIIVEVLDTNDHAPRFTKIYVT-EVPENAPIGFSVIQIVATDEDAGLNAVIEYTIIGH 955 Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN-DVRVEILVTDVN 788 + FS++ G+ L LD E + + +V A+ W+ V I +TDVN Sbjct: 956 NSEFPFSIDKTTGT----LFVSHPLDRED--QDHYIVKVNANDSAWSISTDVTIDITDVN 1009 Query: 789 DNAPVMKD--FQIIFNNYK--DCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNE 844 DNAP+ + + K + F + +V A D D+ + Q L +N Sbjct: 1010 DNAPIFSQPVYSVTIPEMKMHEVFIL----QVSATDRDLGENAQVLYFINPPNELFFVNA 1065 Query: 845 TTGSMT 850 +TG ++ Sbjct: 1066 STGEIS 1071 Score = 316 bits (776), Expect = 6e-84 Identities = 244/882 (27%), Positives = 409/882 (46%), Gaps = 47/882 (5%) Query: 18 DHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXX 77 D + + +M +VR S + ++ + ++A + + +VTA+TL ++ Sbjct: 683 DGAEMPKMDTTTLTVRFWNDSYFPKIAVQVYKNSLFEDAPIGTLVAIVTAETL--KNVSV 740 Query: 78 XXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIH 137 +VF + +G L + LD E + ++V+A D P SS A +H Sbjct: 741 YFYLPSGNFGEVFELHPSTGELTIKDPLDFETNMYFHLIVEARDSGIPP---FSSYAELH 797 Query: 138 VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQ 197 +NI D NDN P FS+ Y V E+++ + + + A DAD G + + Y I+GGN + Sbjct: 798 LNISDVNDNPPVFSQDIYKCQVYENLASSR---VCNVLAKDADSGVFAEVLYFILGGNIE 854 Query: 198 MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF 257 F ID G +S K LD EQ+ Y L I+A D + S +++ + D ND+APRF Sbjct: 855 STFKIDKNRGTLSTTKRLDREQIPYYNLSIKAIDKENNSLLAVASIIVEVLDTNDHAPRF 914 Query: 258 YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317 T ++ V EN PIG+S++++ A D D G+NA + YT+ N + P +ID +G Sbjct: 915 -TKIYVTEVPENAPIGFSVIQIVATDEDAGLNAVIEYTIIGH----NSEFPFSIDKTTGT 969 Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377 ++ S LDRE Q Y + V A D S + F Y V + E Sbjct: 970 LFVSHPLDREDQDHYIVKVNANDSA---WSISTDVTIDITDVNDNAPIFSQPVYSVTIPE 1026 Query: 378 DEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435 + ++ ++ATD D E+ ++ Y I N F + + G L + Sbjct: 1027 MKMHEVFILQVSATDRDLGENAQVLYFINPPNEL--FFVNASTGEISNKQTIALAELESE 1084 Query: 436 RYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 + V A+D G S +++V + + N + P+F S+ +G+ V+ VSA Sbjct: 1085 IFTFMVVASDCGNVSLNSSSIVSVALVQYNYFPPMFLPFKPLVSIPLTLDVGSEVIQVSA 1144 Query: 494 TDSD-VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552 D D + +N + Y S + F + +G + N L L +T Sbjct: 1145 VDQDYLQMNNSVEYFNSG-------GNGSLYFQVEQNSGRVLVNATLANSLNMILTLEIT 1197 Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612 A+D G+P ++ T++ V+ N P F + ED VG+ + ++ D DVG Sbjct: 1198 AKDKGLPPIAAQTEISFEVIQENQFAPQFLNSQVEFFVPEDLPVGSVIGKIQGKDKDVGS 1257 Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672 NG I Y D + E G F I+ SG+I K LD E TH L +A DGG P+ + Sbjct: 1258 NGVISYSFDGGN-ENGLFSIEHFSGLIMLVKGLDFEKSETHHLSVIAKDGGWRPKKGRLN 1316 Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732 V + + D+ND+PP+F S + EN+ IGT + ++ A D D G ++ + YS+ G D+ Sbjct: 1317 VTVYVTDLNDNPPIFTSKDYVASVLENAFIGTLVLQVWAKDSDTGIHSQITYSVIAG-DA 1375 Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--PPLWNDV-RVEILVTDVND 789 FSL+++ GS + T+ DYE + +EL ++A + PP D+ R+ I V VN+ Sbjct: 1376 QLFSLDSKNGS----ITTLEIFDYEQ-NQHFELTVKATNIGPPFLFDIARIYIQVVGVNE 1430 Query: 790 NAPVMKDFQIIFNNYKDCFPVGPFGRVPA--YDADVTDKLQYRILSGNNANLILLNETTG 847 P + F+ + P G + A YD ++ Y ++ + + ++++ TG Sbjct: 1431 FIPAFQRHLYNFSVSEALMPQTEIGSILATDYDLGPDGEVFYILVGQSKKSNFVVDKHTG 1490 Query: 848 SMTLSPQLNTNVPKLATMEV-----SVTDGVNEIKAMMQLSV 884 + ++ L T + + V G N +A++ LS+ Sbjct: 1491 KIYIAKDLKTRLKNEDVLHVLAKNRGAITGFNVDEALIHLSI 1532 Score = 308 bits (755), Expect = 2e-81 Identities = 261/875 (29%), Positives = 404/875 (46%), Gaps = 71/875 (8%) Query: 12 NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71 NV++ ND+ PVF + AS+ E + G L+L +D D G EVE VT+ L Sbjct: 76 NVINVNDNPPVFSQNAFYASIPEDSPVGMCFLSLNVSDPDEGIYGEVELA---VTSGDL- 131 Query: 72 PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131 ++ F I+ + G L A LDRE A Y+++V+A D A P RLS Sbjct: 132 ---------------ENKFSIN-QEGTLCLIAELDRETNAMYSLIVQANDHALPTETRLS 175 Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191 S+ + + + D NDN P F TVS E+ + + I+ATDAD G+N ++ Sbjct: 176 SSVHVTIYLKDVNDN-PPFITTPSTVSFPENAPL--QSAVTVIQATDADAGSNGEFVFSF 232 Query: 192 IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251 + FSI+S +G V L K LD E R++++ +D G P L + + DVN Sbjct: 233 ESAKDE-SFSINSSTGVVYLQKPLDRETKDVIRVMLKVKDKGIPPLYTLMNLTVLVEDVN 291 Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311 D+ P F S++ SV E+ P G +++V A D D G N + +++++ + + Sbjct: 292 DHNPEFTQSIYSLSVYEDAPRGTILLKVGASDRDIGPNGLVRFSISESGF--------MV 343 Query: 312 DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ- 370 D G V ++DRE Y V A D GD RS TAT F+P Sbjct: 344 DSVLGIVLVIEKMDREKTPFYSFSVFAVDQGDVQRSTTATINITVLDVNDCVPNFLPESL 403 Query: 371 --YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 + +E ED T + + D + +L Y I GN FS+ S G I + + Sbjct: 404 IIHVLENGEDSSQHTHQIHASDEDLGANGQLTYSIESGNDENLFSLHS---NGTIQILED 460 Query: 429 LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD + + +YVL V A DSG + T + I + D N+ PVFE +TA V ED+P+GT Sbjct: 461 LDREVKSQYVLKVIAVDSGFPSLTGTGTLIIVVDDINDNIPVFEKDIFTAHVLEDSPVGT 520 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 + L ++A+D D G Q+ YSL D F IN +G + T LDRET+ Sbjct: 521 SFLRITASDLDDGTIGQLRYSLEG---------LDFPFFINATSGDLFTVSALDRETVPF 571 Query: 547 YLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 Y V DG LS + V +++ DVNDN P F Y ANI G+ V V A Sbjct: 572 YRFLVIVSDGHPTMPLSSSAAVVVTIEDVNDNFPSFLYGPYVANIPFGLTKGSVVCTVMA 631 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 DADV LN ++++ L + + F I+ +G + + +++R + T D+ DG Sbjct: 632 EDADVELNAKLNFSL--QGQHAHLFSINSHTGTVLISDSINRRNDITIDVHVQ--DGAEM 687 Query: 666 PQSSTVIVHIKIEDINDSP-PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 P+ T + ++ NDS P + E++PIGT + + A + N V++ Sbjct: 688 PKMDTTTLTVRF--WNDSYFPKIAVQVYKNSLFEDAPIGTLVAIVTA---ETLKNVSVYF 742 Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVE 781 + G+ F L G EL LD+E+ + L++ A PP + + Sbjct: 743 YLPSGNFGEVFELHPSTG----ELTIKDPLDFET-NMYFHLIVEARDSGIPPFSSYAELH 797 Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANL 839 + ++DVNDN PV Y++ V A DAD V ++ Y IL GN + Sbjct: 798 LNISDVNDNPPVFSQDIYKCQVYEN-LASSRVCNVLAKDADSGVFAEVLYFILGGNIEST 856 Query: 840 ILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN 874 +++ G+++ + +L+ + + D N Sbjct: 857 FKIDKNRGTLSTTKRLDREQIPYYNLSIKAIDKEN 891 Score = 297 bits (730), Expect = 2e-78 Identities = 237/791 (29%), Positives = 380/791 (48%), Gaps = 56/791 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD NDH+P F + Y V E A G +V+ + ATD+D G NA +EYTI + ++ Sbjct: 902 VEVLDTNDHAPRF-TKIYVTEVPENAPIGFSVIQIVATDEDAGLNAVIEYTI--IGHNSE 958 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P F ID +G L LDRE Y V V A D A +S Sbjct: 959 FP-----------------FSIDKTTGTLFVSHPLDREDQDHYIVKVNANDSAWSIS--- 998 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + ++I D NDN P FS+ Y+V++ E I ++ ATD D+G N+ + Y Sbjct: 999 ---TDVTIDITDVNDNAPIFSQPVYSVTIPE--MKMHEVFILQVSATDRDLGENAQVLYF 1053 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS--YRLVIRAQDGGSPSRSNTTQLLINIR 248 I N F +++ +G++S +T+ ++ S + ++ A D G+ S ++++ + + + Sbjct: 1054 INPPNE--LFFVNASTGEISNKQTIALAELESEIFTFMVVASDCGNVSLNSSSIVSVALV 1111 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 N P F S+ + +G +++V A D D ++ ++ + GN L Sbjct: 1112 QYNYFPPMFLPFKPLVSIPLTLDVGSEVIQVSAVDQD---YLQMNNSVEYFNSGGNGSLY 1168 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 ++ SG V + L L +TA D G PP +A F+ Sbjct: 1169 FQVEQNSGRVLVNATLANSLNMILTLEITAKDKGLPPIAAQTEISFEVIQENQFAPQFLN 1228 Query: 369 GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 Q E + ED P G+ + + D D + + Y GGN G FSI ++ GLI + Sbjct: 1229 SQVEFFVPEDLPVGSVIGKIQGKDKDVGSNGVISYSFDGGNENGLFSI--EHFSGLIMLV 1286 Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPI 484 + LDF++ + L+V A D G R V + +TD N+ P+F + Y ASV E+A I Sbjct: 1287 KGLDFEKSETHHLSVIAKDGGWRPKKGRLNVTVYVTDLNDNPPIFTSKDYVASVLENAFI 1346 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 GT VL V A DSD GI++QITYS+ +A Q F ++ + G+ITT ++ D E Sbjct: 1347 GTLVLQVWAKDSDTGIHSQITYSV--------IAGDAQLFSLDSKNGSITTLEIFDYEQN 1398 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 + LTV A + G P L D + I VV VN+ P F++ LY ++ E + T + + Sbjct: 1399 QHFELTVKATNIGPPFLFDIARIYIQVVGVNEFIPAFQRHLYNFSVSEALMPQTEIGSIL 1458 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG- 663 ATD D+G +G + Y L + + + +FV+D +G I K L L +A + G Sbjct: 1459 ATDYDLGPDGEVFYILVGQSK-KSNFVVDKHTGKIYIAKDLKTRLKNEDVLHVLAKNRGA 1517 Query: 664 -TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN-AV 721 T ++H+ I D ND PP F+S +SE+ IGT+I +++A DPD + Sbjct: 1518 ITGFNVDEALIHLSILDEND-PPEFDSMLYIVAVSEDISIGTSIAKVKAVDPDVILEWSR 1576 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781 YSI+ G+ ++SF ++ G + + +D + + + + SP + +V Sbjct: 1577 FSYSIEHGNINSSFIIDPVSG--VISVNSHLDREIWAIYNLTVIAVDEGSPSVTGSTKVA 1634 Query: 782 ILVTDVNDNAP 792 I V D+ND+ P Sbjct: 1635 ITVNDINDSPP 1645 Score = 270 bits (663), Expect = 3e-70 Identities = 223/782 (28%), Positives = 360/782 (46%), Gaps = 57/782 (7%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +F ++ SG L +LD E + RY +L R+ ++ N+I+ NDN P Sbjct: 31 LFLLNPHSGEFLLSRALDFE-IERYYILTAGAQHGDSELIRVR----VYFNVINVNDNPP 85 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 FS+ + S+ ED V + +D D G + A+ G+ + +FSI+ G Sbjct: 86 VFSQNAFYASIPEDSPV--GMCFLSLNVSDPDEGIYGEVELAVTSGDLENKFSINQ-EGT 142 Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSR---SNTTQLLINIRDVNDNAPRFYTSLFQES 265 + L+ LD E Y L+++A D P+ S++ + I ++DVNDN P F T+ S Sbjct: 143 LCLIAELDRETNAMYSLIVQANDHALPTETRLSSSVHVTIYLKDVNDNPP-FITTPSTVS 201 Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325 EN P+ ++ +QA DAD G N E ++ + D +I+ +G VY LD Sbjct: 202 FPENAPLQSAVTVIQATDADAGSNGEFVFS-----FESAKDESFSINSSTGVVYLQKPLD 256 Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 RET+ ++++ D G PP F Y + + ED P GT + Sbjct: 257 RETKDVIRVMLKVKDKGIPPLYTLMNLTVLVEDVNDHNPEFTQSIYSLSVYEDAPRGTIL 316 Query: 386 VTLTATDADEDNRLHYEITGGNTRGRFSITSQNG------RGLITVAQPLDFKQERRYVL 439 + + A+D D G N RFSI S++G G++ V + +D ++ Y Sbjct: 317 LKVGASDRD---------IGPNGLVRFSI-SESGFMVDSVLGIVLVIEKMDREKTPFYSF 366 Query: 440 TVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT-VLVVSATDS 496 +V A D G RS TA + I + D N+ P F V E+ + + A+D Sbjct: 367 SVFAVDQGDVQRSTTATINITVLDVNDCVPNFLPESLIIHVLENGEDSSQHTHQIHASDE 426 Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556 D+G N Q+TYS+ S + H G I + LDRE S Y+L V A D Sbjct: 427 DLGANGQLTYSIESGNDENLFSLHSN--------GTIQILEDLDREVKSQYVLKVIAVDS 478 Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616 G PSL+ T + I V D+NDN PVF++ ++TA+++ED+ VGTS ++ A+D D G G++ Sbjct: 479 GFPSLTGTGTLIIVVDDINDNIPVFEKDIFTAHVLEDSPVGTSFLRITASDLDDGTIGQL 538 Query: 617 HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG-GTPPQSSTVIVHI 675 Y L+ D F I+ SG + T ALDRE+V + + DG T P SS+ V + Sbjct: 539 RYSLEGLD---FPFFINATSGDLFTVSALDRETVPFYRFLVIVSDGHPTMPLSSSAAVVV 595 Query: 676 KIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735 IED+ND+ P F I G+ + + A D D NA +++S++ G ++ F Sbjct: 596 TIEDVNDNFPSFLYGPYVANIPFGLTKGSVVCTVMAEDADVELNAKLNFSLQ-GQHAHLF 654 Query: 736 SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEIL-VTDVNDNAPVM 794 S+ + G T++ D + R + + + L V ND+ Sbjct: 655 SINSHTG-------TVLISDSINRRNDITIDVHVQDGAEMPKMDTTTLTVRFWNDSYFPK 707 Query: 795 KDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQ 854 Q+ N+ + P+G + + + + + SGN + L+ +TG +T+ Sbjct: 708 IAVQVYKNSLFEDAPIGTLVAIVTAETLKNVSVYFYLPSGNFGEVFELHPSTGELTIKDP 767 Query: 855 LN 856 L+ Sbjct: 768 LD 769 Score = 263 bits (645), Expect = 4e-68 Identities = 246/875 (28%), Positives = 389/875 (44%), Gaps = 72/875 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+ PVFE + A V E + GT+ L + A+D D G ++ Y++E Sbjct: 491 IVVDDINDNIPVFEKDIFTAHVLEDSPVGTSFLRITASDLDDGTIGQLRYSLE------- 543 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F I+ SG L T ++LDRE V Y LV +D P L Sbjct: 544 --------------GLDFPFFINATSGDLFTVSALDRETVPFYRFLVIVSD-GHPTMP-L 587 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SS+A + V I D NDN+P F Y ++ +T V+ + A DADV N+ + ++ Sbjct: 588 SSSAAVVVTIEDVNDNFPSFLYGPYVANI--PFGLTKGSVVCTVMAEDADVELNAKLNFS 645 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + G + + FSI+S +G V + +++ + + + QDG + +TT L +R Sbjct: 646 LQGQHAHL-FSINSHTGTVLISDSIN--RRNDITIDVHVQDGAEMPKMDTTTL--TVRFW 700 Query: 251 NDN-APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 ND+ P+ +++ S+ E+ PIG + V A+ N + + + +GN Sbjct: 701 NDSYFPKIAVQVYKNSLFEDAPIGTLVAIV---TAETLKNVSVYFYLP----SGNFGEVF 753 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 + P +G + LD ET + L+V A D G PP S+ A F Sbjct: 754 ELHPSTGELTIKDPLDFETNMYFHLIVEARDSGIPPFSSYAELHLNISDVNDNPPVFSQD 813 Query: 370 QYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 Y+ ++ E+ + V + A DAD + Y I GGN F I RG ++ + Sbjct: 814 IYKCQVYEN-LASSRVCNVLAKDADSGVFAEVLYFILGGNIESTFKI--DKNRGTLSTTK 870 Query: 428 PLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 LD +Q Y L++ A D S A + + + D N++AP F Y V E+APIG Sbjct: 871 RLDREQIPYYNLSIKAIDKENNSLLAVASIIVEVLDTNDHAPRFTKI-YVTEVPENAPIG 929 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ-QFVINPQTGAITTNKLLDRETM 544 +V+ + ATD D G+NA I Y++ + H+ + F I+ TG + + LDRE Sbjct: 930 FSVIQIVATDEDAGLNAVIEYTI--------IGHNSEFPFSIDKTTGTLFVSHPLDREDQ 981 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 Y++ V A D + S +TDV I + DVNDN P+F Q +Y+ I E + + QV Sbjct: 982 DHYIVKVNANDS---AWSISTDVTIDITDVNDNAPIFSQPVYSVTIPEMKMHEVFILQVS 1038 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK--ALDRESVATHDLKAVAIDG 662 ATD D+G N ++ Y ++P + F ++ ++G I + AL VA D Sbjct: 1039 ATDRDLGENAQVLYFINPPNE---LFFVNASTGEISNKQTIALAELESEIFTFMVVASDC 1095 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE-GPNAV 721 G +S+ IV + + N PP+F I +G+ + ++ A D D N Sbjct: 1096 GNVSLNSSSIVSVALVQYNYFPPMFLPFKPLVSIPLTLDVGSEVIQVSAVDQDYLQMNNS 1155 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR-AASPPLWNDVRV 780 V Y GG+ S F +E G LV + + E+ + PP+ + Sbjct: 1156 VEYFNSGGNGSLYFQVEQNSG---RVLVNATLANSLNMILTLEITAKDKGLPPIAAQTEI 1212 Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADVTDK--LQYRILSGNNA 837 V N AP + Q+ F +D PVG G++ D DV + Y GN Sbjct: 1213 SFEVIQENQFAPQFLNSQVEFFVPED-LPVGSVIGKIQGKDKDVGSNGVISYSFDGGNEN 1271 Query: 838 NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 L + +G + L L+ + + V DG Sbjct: 1272 GLFSIEHFSGLIMLVKGLDFEKSETHHLSVIAKDG 1306 Score = 260 bits (636), Expect = 5e-67 Identities = 200/684 (29%), Positives = 334/684 (48%), Gaps = 42/684 (6%) Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259 F ++ SG+ L + LD+E R Y L AQ G S ++ N+ +VNDN P F Sbjct: 32 FLLNPHSGEFLLSRALDFEIERYYILTAGAQHGDS--ELIRVRVYFNVINVNDNPPVFSQ 89 Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319 + F S+ E+ P+G + + D DEG+ E+ +T +G+++ +I+ + G + Sbjct: 90 NAFYASIPEDSPVGMCFLSLNVSDPDEGIYGEVELAVT----SGDLENKFSIN-QEGTLC 144 Query: 320 TSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377 +LDRET A Y L+V A D P R +++ F+ V E Sbjct: 145 LIAELDRETNAMYSLIVQANDHALPTETRLSSSVHVTIYLKDVNDNPPFITTPSTVSFPE 204 Query: 378 DEPPGTPVVTLTATDADEDNRLHYEITGGNTRGR-FSITSQNGRGLITVAQPLDFKQERR 436 + P + V + ATDAD + + + + + FSI S G ++ + +PLD + + Sbjct: 205 NAPLQSAVTVIQATDADAGSNGEFVFSFESAKDESFSINSSTG--VVYLQKPLDRETKDV 262 Query: 437 YVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494 + + D G ++ + + D N++ P F + Y+ SV+EDAP GT +L V A+ Sbjct: 263 IRVMLKVKDKGIPPLYTLMNLTVLVEDVNDHNPEFTQSIYSLSVYEDAPRGTILLKVGAS 322 Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554 D D+G N + +S+S + F+++ G + + +DRE Y +V A Sbjct: 323 DRDIGPNGLVRFSIS-----------ESGFMVDSVLGIVLVIEKMDREKTPFYSFSVFAV 371 Query: 555 DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS-VSQVGATDADVGLN 613 D G S T + I+V+DVND P F + +++E+ + Q+ A+D D+G N Sbjct: 372 DQGDVQRSTTATINITVLDVNDCVPNFLPESLIIHVLENGEDSSQHTHQIHASDEDLGAN 431 Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673 G++ Y ++ +E F + ++G I+ + LDRE + + LK +A+D G P + T + Sbjct: 432 GQLTYSIE-SGNDENLFSLH-SNGTIQILEDLDREVKSQYVLKVIAVDSGFPSLTGTGTL 489 Query: 674 HIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN 733 I ++DIND+ PVFE D T ++ E+SP+GT+ I A D D+G + YS++G D Sbjct: 490 IIVVDDINDNIPVFEKDIFTAHVLEDSPVGTSFLRITASDLDDGTIGQLRYSLEGLDFP- 548 Query: 734 SFSLETRQGSDKAELVTMVDLDYES-PRKKYELVIRAASP--PLWNDVRVEILVTDVNDN 790 F + G +L T+ LD E+ P ++ +++ P PL + V + + DVNDN Sbjct: 549 -FFINATSG----DLFTVSALDRETVPFYRFLVIVSDGHPTMPLSSSAAVVVTIEDVNDN 603 Query: 791 APVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGS 848 P + N V A DADV KL + L G +A+L +N TG+ Sbjct: 604 FPSFLYGPYVANIPFGLTKGSVVCTVMAEDADVELNAKLNFS-LQGQHAHLFSINSHTGT 662 Query: 849 MTLSPQLNTNVPKLATMEVSVTDG 872 + +S +N T++V V DG Sbjct: 663 VLISDSINRR--NDITIDVHVQDG 684 Score = 120 bits (289), Expect = 6e-25 Identities = 99/329 (30%), Positives = 156/329 (47%), Gaps = 15/329 (4%) Query: 501 NAQITYSLSSEISNEAVAHHDQQ--FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558 + + YS ++ S +V D F++NP +G ++ LD E Y+LT A+ G Sbjct: 7 HVEAVYSEKNKTSVYSVQEDDGDGLFLLNPHSGEFLLSRALDFEIERYYILTAGAQHGDS 66 Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618 + V +V++VNDN PVF Q + A+I ED+ VG + +D D G+ G + Sbjct: 67 ELI--RVRVYFNVINVNDNPPVFSQNAFYASIPEDSPVGMCFLSLNVSDPDEGIYGEVEL 124 Query: 619 ELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ---SSTVIVHI 675 + D E F I+ G + LDRE+ A + L A D P + SS+V V I Sbjct: 125 AVTSGDL-ENKFSIN-QEGTLCLIAELDRETNAMYSLIVQANDHALPTETRLSSSVHVTI 182 Query: 676 KIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735 ++D+ND+PP F + T EN+P+ + + I+A D D G N +S + D SF Sbjct: 183 YLKDVNDNPP-FITTPSTVSFPENAPLQSAVTVIQATDADAGSNGEFVFSFESAKD-ESF 240 Query: 736 SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMK 795 S+ + G L +D + + + V PPL+ + + +LV DVND+ P Sbjct: 241 SINSSTG--VVYLQKPLDRETKDVIRVMLKVKDKGIPPLYTLMNLTVLVEDVNDHNPEFT 298 Query: 796 DFQIIFNNYKDCFPVGP-FGRVPAYDADV 823 + Y+D P G +V A D D+ Sbjct: 299 QSIYSLSVYEDA-PRGTILLKVGASDRDI 326 Score = 56.4 bits (130), Expect = 1e-05 Identities = 55/258 (21%), Positives = 99/258 (38%), Gaps = 20/258 (7%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPL 1369 C + C + C NG C + +ICDC G+ G + + F + + PL Sbjct: 2031 CTIVDNECQTVVCLNGGTCWNRQGGFICDCSPGYEGVSGVNCDEQSYGFQELSYIEYPPL 2090 Query: 1370 LRPIQLPWL-------NALSIRTRQRDAF--VMSIQLKSGLLHYSYNGETMYLPMAT--- 1417 +L NAL + + + +++++ SG L SY+ + + + T Sbjct: 2091 DPQYNFIYLEFATVQQNALLLYNHGKPSTSDFLALEILSGRLFLSYDLGSGVIRLETGKI 2150 Query: 1418 LSDGAWHRIEIKWLGTD-ISVTVDYGLRTVLMPMLANKIQGQY-IGKILIGGLDTTAGLL 1475 ++DG +H I + L D SV G T N+ + + GG+ + +L Sbjct: 2151 IADGLFHNISMASLEIDNCSVYEPQGFCTTQTGATGNQRTLEVSSNNMTFGGVKSIDAIL 2210 Query: 1476 ASDVGF--FEGCIQDVRIGTAQSLLNRPTVRENVRDGCQSRAD---CMLSICPPYSKCVT 1530 + F GC++++++ + + N+ C R D C ++C C Sbjct: 2211 LRQIRTHDFVGCMRNLQVNNIRPDSLKSLASHNILPRC-PRTDIPPCEAAVCLNEGVCQD 2269 Query: 1531 SWDSSTCTCEAGRVGPQC 1548 W C C GP C Sbjct: 2270 QWSHHRCQCRDHFTGPSC 2287 Score = 39.9 bits (89), Expect = 0.99 Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 1/73 (1%) Query: 1142 LLYNGRYNERHDFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEI 1201 +L +G+ + F ++E + G P F+ G + E++VEGNV DG WH + + Sbjct: 2322 ILDSGKEGDSLGFDSVE-IKMRTISDGKPLYMFTNVTSGHQLELSVEGNVSDGQWHVLHL 2380 Query: 1202 EYFNRTITMILDD 1214 ++ LDD Sbjct: 2381 RRRGSLFSLFLDD 2393 >UniRef50_A7SLL0 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1781 Score = 367 bits (904), Expect = 2e-99 Identities = 317/1111 (28%), Positives = 498/1111 (44%), Gaps = 103/1111 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NVLD NDH+PVF V+E SGTTV+ + A D D+G NA+V Y+ ++ TL Sbjct: 420 VNVLDQNDHAPVFTPATLTVKVQEDTGSGTTVIKVSAVDGDVGSNADVTYSTGMI---TL 476 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N R+ A ++L + Y + V+A + P Sbjct: 477 N-----------------------RAIAFKPFSALPNPNI--YNLTVRARNIYPP---HY 508 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA-DVGANSAIRY 189 + A I + ++D ND+ P F + Y + +D I +++A D D G N+ +RY Sbjct: 509 KADAAIQIEVLDTNDHAPVFIKSVYLLFAVQDAG--SGVSIGRVEAVDKFDYGPNALVRY 566 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I GN +F + +G+V + +L + ++Y + +RA D G P S+T + + + + Sbjct: 567 EAISGNGTGRFRVAPETGEVLIASSLRDDVNKTYYIRVRASDMGQPKMSDTAGVYVEVTE 626 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 N + P F +++Q S +E++ +G +++ V A D D G N E++Y + GN Sbjct: 627 RNLHPPVFSKAVYQTSENEDIAVGSALLTVTATDRDFGRNGEISYDII----AGNSQEYF 682 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 I +G +Y S LD E Q Y L V+ATDGG P+++ AT F P Sbjct: 683 GIGLTNGSLYVSKPLDYEHQENYSLNVSATDGGKEPKTSYATVRITLRDVNDNNPVFSPI 742 Query: 370 QYEVELAEDEPPGTPVV-TLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVA 426 +Y ELAE+ P + VV ++ ATD DE + + Y I GG+ + +F I + G TV Sbjct: 743 EYRCELAENTTPRSVVVCSVRATDRDERGQQSVRYSILGGSGKDKFVIDERTGEIRATVE 802 Query: 427 QPLDFKQERRYVLTVSATDSG-----GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 DF+ L ++A D G A V I IT N + PVF + +TA+V E+ Sbjct: 803 --FDFEVTMSSFLMIAAKDEGLSPQRTADPPASVHILITGVNEFLPVFVQSVFTATVAEN 860 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 APIG +VL VSATD D G + + Y L + + Q F ++ TG ++ + LD Sbjct: 861 APIGHSVLRVSATDKDKGPDGVVLYHLLG-------SDNQQGFDLDSNTGTLSVSGDLDN 913 Query: 542 ETMSGYLLTVTARD----GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 E L V A++ PS + ++V D ND P F + +Y+A++ E + +G Sbjct: 914 ERAGIVTLRVIAKNLFQNSVTPSSVAHATIVVTVTDAND-PPRFLKSVYSAHVTEGSRIG 972 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 V+ V A D D + I Y + + +FV+D +G +RT LDRE++A + L Sbjct: 973 HVVTNVTAVDDDSDIRS-IRYGISAGNTGN-AFVMDAVTGFVRTAAELDREAIAEYRLTV 1030 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A D GTPP + + + ++DIND+PP ++EN P GT + + A DPD Sbjct: 1031 TATDNGTPPMTGNATLVVTLDDINDNPPHLTPLPCIGRVTENKPQGTQVMTLNAEDPDLN 1090 Query: 718 PN-AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN 776 PN YSI G D SF L G + T+ LD E + Y + I+ + Sbjct: 1091 PNRGPFKYSI-SGSDYGSFRLNVSSG----VVSTVKSLDREK-QDAYNISIKVTDARGLS 1144 Query: 777 DVR-VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGN 835 V I V D NDN P + + ++ F G V D D+ D + +L+ Sbjct: 1145 AVNFCMIHVEDQNDNRPKATSRDVYVHTFEGKFLGGVVADVRPDDPDIDDLMTCALLNPP 1204 Query: 836 NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNS 895 N + + G+ LS L + + V+ +DG+ + ++ L TE L Sbjct: 1205 QNN--IFSFPRGNCELS-SLAYSQDARFDLSVNGSDGLGAVTYLITLRFLGYTETTLQQG 1261 Query: 896 ITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARR 955 + VRL + FL+ F + A +P + I SV + +++V S R+ Sbjct: 1262 VVVRLRNTNTRDFLANSYHKFTSAVNATLPSGYSS-QIMSVDSSGE---GLVDVLVSVRQ 1317 Query: 956 PDAEVGVAGDPSPHYSPTHLRERVYLH-RTTLARLATVQVLPFDDNIC-VHEPCLNFEEC 1013 + +R+RV H + L + + + D N C CLN EC Sbjct: 1318 GGTLM--------------IRDRVSGHLKDKLVSSSALDIAAVDYNPCTTGNQCLNGGEC 1363 Query: 1014 LTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSIC 1073 + ++ V+S V+ TC C GFTG CE + D + + C Sbjct: 1364 SSAIQASRRGHVVSSTPVVMVTAGYTWKITCSCKPGFTGSQCEESVN------DCNPNPC 1417 Query: 1074 RSGSQCVARREGGILCQGCSIDAAYTTAVCE 1104 R+ C G CS YT +CE Sbjct: 1418 RNEGTC-TDNNGSF---KCSCIPGYTGRLCE 1444 Score = 355 bits (872), Expect = 1e-95 Identities = 265/872 (30%), Positives = 403/872 (46%), Gaps = 66/872 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND++PVF ++ S+ E GTTV+T+ ATD D G NA+V Y Sbjct: 3 ITVQDVNDNAPVFTSDEFTVSIAENVDDGTTVITVTATDPDAGDNAKVSYA--------- 53 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F ID SG + T + DRE Y++ V A+D +P Sbjct: 54 ----------TYGGSHGNKFAIDASSGRIYTTGTFDRETKDDYSINVTASDHGNPSK--- 100 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SST + V + D+NDN P+F Y + ED +V I + A+DAD+G N+ + Y+ Sbjct: 101 SSTCVVLVTVADNNDNSPKFPALHYVFDIAEDAAV--GASIGTVSASDADIGENARLTYS 158 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I+ + FS++ ++G++++ + LD E +Y + + A D G+P S + ++ + + D Sbjct: 159 IVSPE-KATFSMNPVTGEITVGQRLDREGA-NYSIRVTATDLGTPPLSASMEITVIVDDY 216 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 ND+ P F + + + EN G I+ +QA D D GVNAE+ Y TGN + T Sbjct: 217 NDHRPVFLSHIGTVFIDENASPGTEIITLQAVDGDSGVNAEIRYAFV----TGNSNNSFT 272 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I+ +G + T+ LDRET ++ L V A D G P + + F + Sbjct: 273 INSITGRLRTARNLDRETTPRFTLEVLAYDLGVPRKDSVTNVTVVLRDVNDNQPVFTMSE 332 Query: 371 YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 Y E++E +VT+ A D D D + Y IT G G F I G I + Sbjct: 333 YAAEVSEGVVESN-IVTVVAEDRDIGSDGSVTYCITQGREGGLFVINENT--GTIGITAK 389 Query: 429 LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD + + +Y L V ATD G S A V +N+ D N++APVF A T V ED GT Sbjct: 390 LDRETKSKYTLRVQATDGGSPALSSEADVIVNVLDQNDHAPVFTPATLTVKVQEDTGSGT 449 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 TV+ VSA D DVG NA +TYS N A+A + NP Sbjct: 450 TVIKVSAVDGDVGSNADVTYSTGMITLNRAIAFKPFSALPNPNI---------------- 493 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y LTV AR+ P ++I V+D ND+ PVF + +Y ++DA G S+ +V A Sbjct: 494 YNLTVRARNIYPPHYKADAAIQIEVLDTNDHAPVFIKSVYLLFAVQDAGSGVSIGRVEAV 553 Query: 607 DA-DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 D D G N + YE G F + P +G + +L + T+ ++ A D G P Sbjct: 554 DKFDYGPNALVRYEA-ISGNGTGRFRVAPETGEVLIASSLRDDVNKTYYIRVRASDMGQP 612 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 S T V++++ + N PPVF +E+ +G+ + + A D D G N + Y Sbjct: 613 KMSDTAGVYVEVTERNLHPPVFSKAVYQTSENEDIAVGSALLTVTATDRDFGRNGEISYD 672 Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEI 782 I G+ F + GS L LDYE ++ Y L + A P + V I Sbjct: 673 IIAGNSQEYFGIGLTNGS----LYVSKPLDYEH-QENYSLNVSATDGGKEPKTSYATVRI 727 Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADV--TDKLQYRILSGNNANL 839 + DVNDN PV + ++ P V A D D ++Y IL G+ + Sbjct: 728 TLRDVNDNNPVFSPIEYRCELAENTTPRSVVVCSVRATDRDERGQQSVRYSILGGSGKDK 787 Query: 840 ILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 +++E TG + + + + V + + ++ D Sbjct: 788 FVIDERTGEIRATVEFDFEVTMSSFLMIAAKD 819 Score = 324 bits (796), Expect = 2e-86 Identities = 266/887 (29%), Positives = 395/887 (44%), Gaps = 73/887 (8%) Query: 4 PFCIHQQINVL--DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 P +I V+ D NDH PVF + E AS GT ++TL+A D D G NAE+ Y Sbjct: 202 PLSASMEITVIVDDYNDHRPVFLSHIGTVFIDENASPGTEIITLQAVDGDSGVNAEIRYA 261 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121 VT ++ N F I+ +G L T +LDRE R+T+ V A D Sbjct: 262 --FVTGNSNNS-----------------FTINSITGRLRTARNLDRETTPRFTLEVLAYD 302 Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181 P R S + V + D NDN P F+ Y V E + V N I + A D D+ Sbjct: 303 LGVP---RKDSVTNVTVVLRDVNDNQPVFTMSEYAAEVSEGV-VESN--IVTVVAEDRDI 356 Query: 182 GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 G++ ++ Y I G F I+ +G + + LD E Y L ++A DGGSP+ S+ Sbjct: 357 GSDGSVTYCITQGREGGLFVINENTGTIGITAKLDRETKSKYTLRVQATDGGSPALSSEA 416 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 +++N+ D ND+AP F + V E+ G ++++V A D D G NA++TY+ Sbjct: 417 DVIVNVLDQNDHAPVFTPATLTVKVQEDTGSGTTVIKVSAVDGDVGSNADVTYS------ 470 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 TG + L I + + + Y L V A + P A A Sbjct: 471 TGMITLNRAIAFKPFSALPNPNI-------YNLTVRARNIYPPHYKADAAIQIEVLDTND 523 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRL-HYEITGGNTRGRFSITSQN 418 F+ Y + +D G + + A D + N L YE GN GRF + + Sbjct: 524 HAPVFIKSVYLLFAVQDAGSGVSIGRVEAVDKFDYGPNALVRYEAISGNGTGRFRVAPET 583 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTA 476 G + +A L + Y + V A+D G SDTA V + +T+ N + PVF A Y Sbjct: 584 GE--VLIASSLRDDVNKTYYIRVRASDMGQPKMSDTAGVYVEVTERNLHPPVFSKAVYQT 641 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 S ED +G+ +L V+ATD D G N +I+Y + + S E F I G++ + Sbjct: 642 SENEDIAVGSALLTVTATDRDFGRNGEISYDIIAGNSQE-------YFGIGLTNGSLYVS 694 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 K LD E Y L V+A DGG + V I++ DVNDN PVF Y + E+ Sbjct: 695 KPLDYEHQENYSLNVSATDGGKEPKTSYATVRITLRDVNDNNPVFSPIEYRCELAENTTP 754 Query: 597 -GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655 V V ATD D + Y + ++ FVID +G IR D E + L Sbjct: 755 RSVVVCSVRATDRDERGQQSVRYSILGGSGKD-KFVIDERTGEIRATVEFDFEVTMSSFL 813 Query: 656 KAVAIDGGTPPQSST---VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 A D G PQ + VHI I +N+ PVF T ++EN+PIG ++ + A Sbjct: 814 MIAAKDEGLSPQRTADPPASVHILITGVNEFLPVFVQSVFTATVAENAPIGHSVLRVSAT 873 Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI----- 767 D D+GP+ VV Y + G D+ F L++ G+ L DLD E VI Sbjct: 874 DKDKGPDGVVLYHLLGSDNQQGFDLDSNTGT----LSVSGDLDNERAGIVTLRVIAKNLF 929 Query: 768 -RAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTD 825 + +P + + VTD ND +K + + + +G V A D D Sbjct: 930 QNSVTPSSVAHATIVVTVTDANDPPRFLK--SVYSAHVTEGSRIGHVVTNVTAVDDDSDI 987 Query: 826 K-LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + ++Y I +GN N +++ TG + + +L+ + V+ TD Sbjct: 988 RSIRYGISAGNTGNAFVMDAVTGFVRTAAELDREAIAEYRLTVTATD 1034 Score = 324 bits (795), Expect = 3e-86 Identities = 232/752 (30%), Positives = 357/752 (47%), Gaps = 43/752 (5%) Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195 + + + D NDN P F+ +TVS+ E++ D + + ATD D G N+ + YA GG+ Sbjct: 1 VTITVQDVNDNAPVFTSDEFTVSIAENVD--DGTTVITVTATDPDAGDNAKVSYATYGGS 58 Query: 196 TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP 255 +F+ID+ SG + T D E Y + + A D G+PS+S+T +L+ + D NDN+P Sbjct: 59 HGNKFAIDASSGRIYTTGTFDRETKDDYSINVTASDHGNPSKSSTCVVLVTVADNNDNSP 118 Query: 256 RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315 +F + ++E+ +G SI V A DAD G NA LTY++ + +++P + Sbjct: 119 KFPALHYVFDIAEDAAVGASIGTVSASDADIGENARLTYSIVSPE-----KATFSMNPVT 173 Query: 316 GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375 G + +LDRE A Y + VTATD G PP SA+ F+ V + Sbjct: 174 GEITVGQRLDRE-GANYSIRVTATDLGTPPLSASMEITVIVDDYNDHRPVFLSHIGTVFI 232 Query: 376 AEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ 433 E+ PGT ++TL A D D + + Y GN+ F+I S GR + A+ LD + Sbjct: 233 DENASPGTEIITLQAVDGDSGVNAEIRYAFVTGNSNNSFTINSITGR--LRTARNLDRET 290 Query: 434 ERRYVLTVSATDSG-GRSDTAM-VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491 R+ L V A D G R D+ V + + D N+ PVF + Y A V E + + ++ V Sbjct: 291 TPRFTLEVLAYDLGVPRKDSVTNVTVVLRDVNDNQPVFTMSEYAAEVSEGV-VESNIVTV 349 Query: 492 SATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTV 551 A D D+G + +TY ++ FVIN TG I LDRET S Y L V Sbjct: 350 VAEDRDIGSDGSVTYCITQ-------GREGGLFVINENTGTIGITAKLDRETKSKYTLRV 402 Query: 552 TARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG 611 A DGG P+LS DV ++V+D ND+ PVF T + ED GT+V +V A D DVG Sbjct: 403 QATDGGSPALSSEADVIVNVLDQNDHAPVFTPATLTVKVQEDTGSGTTVIKVSAVDGDVG 462 Query: 612 LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671 N + Y G ++ A + AL ++ ++L A + P + Sbjct: 463 SNADVTY-------STGMITLNRAI-AFKPFSALPNPNI--YNLTVRARNIYPPHYKADA 512 Query: 672 IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP-DEGPNAVVHYSIKGGD 730 + I++ D ND PVF + +++ G +IG + A D D GPNA+V Y G+ Sbjct: 513 AIQIEVLDTNDHAPVFIKSVYLLFAVQDAGSGVSIGRVEAVDKFDYGPNALVRYEAISGN 572 Query: 731 DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDV 787 + F + G V + + K Y + +RA+ P + + V + VT+ Sbjct: 573 GTGRFRVAPETGE-----VLIASSLRDDVNKTYYIRVRASDMGQPKMSDTAGVYVEVTER 627 Query: 788 NDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNET 845 N + PV + +D V A D D ++ Y I++GN+ + T Sbjct: 628 NLHPPVFSKAVYQTSENEDIAVGSALLTVTATDRDFGRNGEISYDIIAGNSQEYFGIGLT 687 Query: 846 TGSMTLSPQLNTNVPKLATMEVSVTDGVNEIK 877 GS+ +S L+ + ++ VS TDG E K Sbjct: 688 NGSLYVSKPLDYEHQENYSLNVSATDGGKEPK 719 Score = 60.5 bits (140), Expect = 7e-07 Identities = 73/297 (24%), Positives = 111/297 (37%), Gaps = 53/297 (17%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPL 1369 C + C S+PC + C DL ++ C C G G+ C S+ FG F P Sbjct: 1481 CDVDINYCQSSPCMYNSTCKDLPTSFECVCDFGGRGERCEISS-----FG------FEPA 1529 Query: 1370 LRPIQLPWLNALSIRTRQRDAFVMSIQLKSGLLHYSYNGETM-------------YLPMA 1416 + P L ++ +T S +GLL Y+ +G YL Sbjct: 1530 SYML-FPTLQGVNQKTYNNITMEFSTSSPNGLLFYNTDGTPAAAADFIALEIVERYLCDR 1588 Query: 1417 TLSDGAWHRIEIKWLGTDISVTVDYGLRTVL--MPMLANKIQGQYIGKILIGGLDTTAGL 1474 ++DG WH + + D VT+ G + + G I + +GG Sbjct: 1589 AVTDGKWHHVTVI---RDKKVTLATGTEFTQREFAVTPHNFLGANIRQWSLGGATQVPSG 1645 Query: 1475 LASDVGFFEGCIQDVRIGTAQSLLNRPT------VREN-VRDGCQSRADCMLSIC---PP 1524 + + F+GC++D++I + +N P R V +GC + C S C Sbjct: 1646 VTLEK--FKGCMEDLKINGVNTPMNGPNRFLSAEARGGAVTEGCVTSGQCQSSPCANNKE 1703 Query: 1525 YSKCVTSWDSSTCTCEAGRVGPQCVSACELGPC-GAARCVPDQTPKGYSCACEPGYT 1580 + C WDS TC A C+ PC A C P Q + + C C YT Sbjct: 1704 KTACYEDWDSYTCVSAA---------PCQPDPCKNNATCKP-QKDETFLCVCVGNYT 1750 Score = 50.4 bits (115), Expect = 7e-04 Identities = 26/72 (36%), Positives = 33/72 (45%), Gaps = 4/72 (5%) Query: 1512 QSRADCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTP 1568 +S DC + C C + S C+C G G C + C PC A D TP Sbjct: 1407 ESVNDCNPNPCRNEGTCTDNNGSFKCSCIPGYTGRLCESDIDECLTNPCKHASAC-DNTP 1465 Query: 1569 KGYSCACEPGYT 1580 GY+C C+PGYT Sbjct: 1466 GGYTCTCKPGYT 1477 Score = 48.8 bits (111), Expect = 0.002 Identities = 36/124 (29%), Positives = 59/124 (47%), Gaps = 15/124 (12%) Query: 1042 FTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTA 1101 +TC C G+TG NC+ + C+ S C S C + C D Sbjct: 1468 YTCTCKPGYTGQNCDVDIN--YCQ----SSPCMYNSTC----KDLPTSFECVCDFGGRGE 1517 Query: 1102 VCELRARSFPVSSFLTFP---GLKRRHRIHLKLKFATQTTSGLLLYN--GRYNERHDFLA 1156 CE+ + F +S++ FP G+ ++ ++ ++F+T + +GLL YN G DF+A Sbjct: 1518 RCEISSFGFEPASYMLFPTLQGVNQKTYNNITMEFSTSSPNGLLFYNTDGTPAAAADFIA 1577 Query: 1157 LELV 1160 LE+V Sbjct: 1578 LEIV 1581 Score = 41.9 bits (94), Expect = 0.25 Identities = 22/72 (30%), Positives = 32/72 (44%), Gaps = 5/72 (6%) Query: 1511 CQSRAD-CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQ 1566 C+S D C+ + C S C + TCTC+ G G C ++ C+ PC D Sbjct: 1443 CESDIDECLTNPCKHASACDNTPGGYTCTCKPGYTGQNCDVDINYCQSSPCMYNSTCKD- 1501 Query: 1567 TPKGYSCACEPG 1578 P + C C+ G Sbjct: 1502 LPTSFECVCDFG 1513 Score = 40.7 bits (91), Expect = 0.57 Identities = 42/149 (28%), Positives = 57/149 (38%), Gaps = 30/149 (20%) Query: 1536 TCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSCACEPGYTLTTSGCIESGKE 1592 TC+C+ G G QC V+ C PC D + C+C PGY T ES + Sbjct: 1393 TCSCKPGFTGSQCEESVNDCNPNPCRNEGTCTDNN-GSFKCSCIPGY---TGRLCESDID 1448 Query: 1593 ECPGGWWGGSACGPC----ACDVTRGYHPHCNKENGKCHCKENHYKPEGTAECLPCQCYA 1648 EC PC ACD T G + C CK + + CQ + Sbjct: 1449 EC--------LTNPCKHASACDNTPGGY--------TCTCKPGYTGQNCDVDINYCQS-S 1491 Query: 1649 AGSENSSCE--AATGQCHCRPGVIGRACD 1675 NS+C+ + +C C G G C+ Sbjct: 1492 PCMYNSTCKDLPTSFECVCDFGGRGERCE 1520 Score = 37.9 bits (84), Expect = 4.0 Identities = 13/39 (33%), Positives = 20/39 (51%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C + PC + + C + Y C CK G+TG++C Sbjct: 1443 CESDIDECLTNPCKHASACDNTPGGYTCTCKPGYTGQNC 1481 Score = 37.1 bits (82), Expect = 7.0 Identities = 40/130 (30%), Positives = 54/130 (41%), Gaps = 32/130 (24%) Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHCNKENG--KCHCK 1629 +C+C+PG+T S C ES + P PC + T C NG KC C Sbjct: 1393 TCSCKPGFT--GSQCEESVNDCNPN---------PCRNEGT------CTDNNGSFKCSCI 1435 Query: 1630 ENHYK---PEGTAECLPCQCYAAGSENSSCEAATG--QCHCRPGVIGRACDACANAYAEV 1684 + ECL C A S+C+ G C C+PG G+ CD N Y + Sbjct: 1436 PGYTGRLCESDIDECLTNPCKHA----SACDNTPGGYTCTCKPGYTGQNCDVDIN-YCQS 1490 Query: 1685 TP---NSGCE 1691 +P NS C+ Sbjct: 1491 SPCMYNSTCK 1500 Score = 37.1 bits (82), Expect = 7.0 Identities = 14/39 (35%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C E + C+ PC N C+D ++ C C G+TG+ C Sbjct: 1405 CEESVNDCNPNPCRNEGTCTDNNGSFKCSCIPGYTGRLC 1443 >UniRef50_Q24292 Cluster: Protein dachsous precursor; n=3; Drosophila melanogaster|Rep: Protein dachsous precursor - Drosophila melanogaster (Fruit fly) Length = 3503 Score = 359 bits (884), Expect = 5e-97 Identities = 254/789 (32%), Positives = 395/789 (50%), Gaps = 70/789 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I V D ND++P + + V E GT + ATD D G N +++Y + + Sbjct: 1419 KIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRL-IRYFPQ 1477 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 LN +FR+D +GAL +A LD E V Y ++V+A DQ+S V++R Sbjct: 1478 LNESQEQA---------MSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTER 1528 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTD----NPVIAKIKATDADVGANS 185 L ++ T+ + I+D ND+ P F + + ++D V+A I A D D G N Sbjct: 1529 LQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNG 1588 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTL-----DYEQVRSYRLVIRAQDGGSPS-RSN 239 + Y I GGN + +F I+S +G + LVK+L D E+ + L+I A+D G P + + Sbjct: 1589 QLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKS 1648 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 + L + ++ ++N PRF ++++ ++ ENVP G +++V A NA L+Y + Sbjct: 1649 SLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIP-- 1706 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG------------------ 341 G + +D + G + T GQ DRE+QA Y L V D Sbjct: 1707 --AGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSD 1764 Query: 342 --GDPPRSA---TATXXXXXXXXXXXXXXFMPGQ-YEVELAEDEPPGTPVVTLTATDADE 395 GD AT F PG Y + + E+ PG + T+ A+D DE Sbjct: 1765 SIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGV-IHTVVASDLDE 1823 Query: 396 DNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG---GRS 450 L Y ITGGN +FSI S +G A+PLD +Q RY L + A+D G R Sbjct: 1824 GPNADLIYSITGGNLGNKFSIDSSSGE---LSARPLDREQHSRYTLQIQASDRGQPKSRQ 1880 Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510 + I + D N+ AP F+ + YT SV EDAP+GT+V+ +SA D+D+G+NA++ YSL++ Sbjct: 1881 GHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLAN 1940 Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL-SDTTDVEI 569 E QF I+ Q+G ITT LDRE + Y V A DGG + S T V+I Sbjct: 1941 ET--------QWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQI 1992 Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE-EG 628 +V+D+NDN P+F++ Y + G ++ +V A DAD+G N I Y L+ ++ Sbjct: 1993 NVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSA 2052 Query: 629 SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV-- 686 F I+P++G + +++L ES L+ VA D G PPQSS ++ + I + PV Sbjct: 2053 KFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLR 2112 Query: 687 FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746 F+++ + ENSP GT + ++ A D G V +S G++ SL++ G + Sbjct: 2113 FQNETYRVMLKENSPSGTRLLQVVALRSD-GRRQKVQFSFGAGNEDGILSLDSLSGEIRV 2171 Query: 747 ELVTMVDLD 755 ++D D Sbjct: 2172 NKPHLLDYD 2180 Score = 332 bits (816), Expect = 8e-89 Identities = 290/928 (31%), Positives = 434/928 (46%), Gaps = 96/928 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVRE-----GASSGTTVLTLKATDQDIGKNAEVEYTIEL 64 ++ + D ND+ PVF ++Y+ S+RE +S T ++ + ATD D G +V Y I Sbjct: 649 KMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRI-- 706 Query: 65 VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVL-VKATDQ 122 V + +FRID +G + + R + + +L + ATD Sbjct: 707 VAGNEAG-----------------IFRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDG 749 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 + R ++ A + ++IID P F + Y V EDI V+ + A DV Sbjct: 750 GNL---RSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDI--PRGTVVGSVIAASGDVA 804 Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 S +RY+I G+ FSI++ SG++ + K LD+E L I+A G P + TQ Sbjct: 805 HRSPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYGH-TQ 863 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 + I + DVNDNAP F S+ + SV E+ +G + A+D D G + ++TY++ + Sbjct: 864 VNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGK 923 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 G ID RSG + S LD E+ ++ L+VTATDGG P S T Sbjct: 924 G----LFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDN 979 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEIT-GGNTRGRFSITSQN- 418 F +Y V ++E ++ + A+D D N R+ Y I G SI+S + Sbjct: 980 PPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDV 1039 Query: 419 --------GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPV 468 G I + PLD + RY LTV ATD+G + A V + + DAN+ P Sbjct: 1040 SQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPK 1099 Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528 F+ + Y + E+ G+ V VV+A+D D+G NA I YSL S+ F ++P Sbjct: 1100 FQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSS---------FQVHP 1150 Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP-VFKQQLYT 587 TG I+T + LDRE Y L V ARD G P S V I V DVNDN P + Q Sbjct: 1151 VTGEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDV 1210 Query: 588 ANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDRE-EGSFVIDPASGVIRTNKAL 645 ++ E+ GT V +V A D D G N I Y + +D + G F IDP SGVIRT L Sbjct: 1211 VSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVL 1270 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 D E + + L A DGG PP+ + ++ +++ D+ND+ P F S L F + E++ +G Sbjct: 1271 DHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHV 1330 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDS-------NSFS---LETRQGSDK--AELVTMVD 753 +G I P E P VV S++ + N + +E D+ LV Sbjct: 1331 VGSI---SPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARL 1387 Query: 754 LDYESPRKKYELVIR-----AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCF 808 LD E + ++ L IR A++ P + + V+I V DVNDNAP I + Sbjct: 1388 LDRE-VQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDL-QVSEAT 1445 Query: 809 PVGP-FGRVPAYDAD--VTDKLQYRIL--------SGNNA-NLILLNETTGSMTLSPQLN 856 PVG A DAD LQYR++ S A +L ++ TG+++L L+ Sbjct: 1446 PVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLD 1505 Query: 857 TNVPKLATMEVSVTDGVNEIKAMMQLSV 884 + + V D + + +Q SV Sbjct: 1506 FEAVQEYLLIVQALDQSSNVTERLQTSV 1533 Score = 331 bits (814), Expect = 1e-88 Identities = 269/892 (30%), Positives = 404/892 (45%), Gaps = 82/892 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 ++++D P+FE +Y V+E GT V ++ A D+ + V Y+I D Sbjct: 762 LSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPD-- 819 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F I+ SG + LD E ++ + ++AT PV Sbjct: 820 -----------------GYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYGHT 862 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +++ + D NDN P+F +SV E + P+ A A D D G++ + Y+ Sbjct: 863 Q----VNIEVEDVNDNAPEFEASMVRISVPESAEL-GAPLYAA-HAHDKDSGSSGQVTYS 916 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 ++ + + F+ID+ SG + L + LDYE + + L++ A DGG PS S +L++++DV Sbjct: 917 LVKESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDV 976 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY--------T 302 NDN P F + +VSE+ I I++V A D D G NA +TY + D + Sbjct: 977 NDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISS 1036 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 +V I P SGW+Y LDRET+ +YQL V ATD G P A Sbjct: 1037 SDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDN 1096 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGR 420 F +YE + E+ G+ V +TA+D D E+ + Y + N+ F + G Sbjct: 1097 DPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINS--SFQVHPVTGE 1154 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAP-VFENAPYTAS 477 I+ +PLD + Y L V A D G RS V+I+++D N+ AP + + S Sbjct: 1155 --ISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVS 1212 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 V E+ P GT V+ V A D D G NA ITYS+ ++ H F I+P +G I T Sbjct: 1213 VREEQPPGTEVVRVRAVDRDHGQNASITYSIVK--GRDSDGH--GLFSIDPTSGVIRTRV 1268 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 +LD E S Y L V A DGG P + + V+D+NDN P F + EDA +G Sbjct: 1269 VLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALG 1328 Query: 598 TSVSQVGATD--ADVGLNG--------RIHYELDP--KDREEGSFVIDPASGVIRTNKAL 645 V + + ADV N R+ Y L+P KD E +F ID SG + + L Sbjct: 1329 HVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLL 1388 Query: 646 DRESVATHDLKAVAID--GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703 DRE + L+ A+D PQSS + V I++ D+ND+ P + D + +SE +P+G Sbjct: 1389 DREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVG 1448 Query: 704 TTIGEIRAHDPDEGPNAVVHYSI------KGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757 T I A D D G N + Y + + SL R S L LD+E Sbjct: 1449 TIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSL-FRMDSLTGALSLQAPLDFE 1507 Query: 758 SPRKKYELVIRA------ASPPLWNDVRVEILVTDVNDNAPVM-----KDFQIIFNNYKD 806 + ++Y L+++A + L V V + + D ND+AP + D Sbjct: 1508 AV-QEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISD 1566 Query: 807 CFPVGP-FGRVPAYDADVTD--KLQYRILSGNNANLILLNETTGSMTLSPQL 855 +G + A D D D +L Y I GN +N TG + L L Sbjct: 1567 ATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSL 1618 Score = 311 bits (764), Expect = 2e-82 Identities = 247/830 (29%), Positives = 386/830 (46%), Gaps = 56/830 (6%) Query: 86 VQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145 V+ ID +G + T+ LDRE A Y+++ A P+S R + V + D+ND Sbjct: 66 VETDLAIDRATGEIRTKVKLDRETRASYSLV------AIPLSGR---NIRVLVTVKDEND 116 Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS- 204 N P F + + + E+ + + A D D+ + RY I+ GN F + S Sbjct: 117 NAPTFPQTSMHIEFPENTPREVKRTL--LPARDLDLEPYNTQRYNIVSGNVNDAFRLSSH 174 Query: 205 ------LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY 258 L D+ + LD E Y L+I A DGG+P + I I+DVNDN P F Sbjct: 175 RERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFN 234 Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV 318 S + +V EN +G S+++V A D D N + Y + + + + IDPR+G + Sbjct: 235 QSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQ--SDKEQMFRIDPRTGAI 292 Query: 319 YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX----XXXXXFMPGQYEVE 374 Y + LD ET+ ++L+V A D G+ P TA F+ + Sbjct: 293 YINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPK 352 Query: 375 LAEDEPPGTPVVTLTATDADEDNRL-HYEITGGNTRGRFSITSQ-NGRGLITVAQPLDFK 432 ++E PG V ++ D D + +T G F++T++ N L+ V PLD + Sbjct: 353 ISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDRE 412 Query: 433 QERRYVLTVSATDSGGRSDTAMVQI--NITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 Y L+V ATD G A I ITD N+ P FE Y A+V E A GT+VL Sbjct: 413 IVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQ 472 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550 V A D D G+N+ +TYSL+ E H Q F I+PQTG ITT +D ET LT Sbjct: 473 VLAHDRDEGLNSALTYSLA-----ETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLT 527 Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610 V ARDGGVP LS T V +++ DVNDNEP+F Q Y ++ E+ VG + +V A+D D Sbjct: 528 VVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDC 587 Query: 611 GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST 670 G+N ++Y + + F + ASG I LD E ++++ +A D G S+T Sbjct: 588 GVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRG--GLSTT 645 Query: 671 VIVHIKIEDINDSPPVFESDCLTFYISE-----NSPIGTTIGEIRAHDPDEGPNAVVHYS 725 ++ +++ D+ND+ PVF + E + T I + A DPD G V Y Sbjct: 646 AMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYR 705 Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN-----DVRV 780 I G+++ F ++ G + +V D S R + ++ ++ N D V Sbjct: 706 IVAGNEAGIFRIDRSTGE-----IFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAVV 760 Query: 781 EILVTDVNDNAPVMKDFQIIFNNY-KDCFPVGP-FGRVPAYDADVTDK--LQYRILSGNN 836 + + D P+ + + +N Y K+ P G G V A DV + ++Y I SG+ Sbjct: 761 FLSIIDAMQRPPIFEKAR--YNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDP 818 Query: 837 ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886 + +G++ ++ L+ + + T G + Q+++ + Sbjct: 819 DGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYGHTQVNIEV 868 Score = 309 bits (759), Expect = 6e-82 Identities = 264/887 (29%), Positives = 391/887 (44%), Gaps = 62/887 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D ND++P F E L A D D+ Y I V+ Sbjct: 109 VTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNI--VSG--- 163 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N DA V +D L LDRE Y++L++A D +P L Sbjct: 164 NVNDAFRLSSHRER--DGVLYLD-----LQISGFLDRETTPGYSLLIEALDGGTP---PL 213 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 T+++ I D NDN P F++ Y +V E+ +V + + ++ A+D D N + YA Sbjct: 214 RGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTS--VLQVYASDTDADENGLVEYA 271 Query: 191 I--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 I + + F ID +G + + K LD+E + LV+ A+D G T + I + Sbjct: 272 INRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVT 331 Query: 249 DVNDNAPR----FYTSLFQESVSENVPIGYSIVRVQAYDADEGVN-AELTYTMTDKDYTG 303 DVNDN P F + +SE+ G + R+ +D D A + T+ D G Sbjct: 332 DVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGD--G 389 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 + L T D V LDRE + Y L V ATD G PP A+ + Sbjct: 390 HFAL-TTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNP 448 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI--TGGNTRGRFSITSQNG 419 F Y + E PGT V+ + A D DE ++ L Y + T F I Q Sbjct: 449 PEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQT- 507 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477 GLIT +D + E LTV A D G S TA V + I D N+ P+F+ + Y S Sbjct: 508 -GLITTRSHIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVS 566 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 V E+ P+G +L VSA+D D G+NA + Y++ H +F + +G I Sbjct: 567 VAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFK------HLTEFEVRSASGEICIAG 620 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LD E S Y V A D G LS T +++ + DVNDN PVF + Y ++ E Sbjct: 621 ELDFERRSSYEFPVLATDRG--GLSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKAS 678 Query: 598 TSVSQ-----VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652 + S V ATD D G G++ Y + E G F ID ++G I + D SV T Sbjct: 679 SQASSTPIVAVVATDPDYGNFGQVSYRI-VAGNEAGIFRIDRSTGEIFVVRP-DMLSVRT 736 Query: 653 ---HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 H L A DGG ++ +V + I D PP+FE +Y+ E+ P GT +G + Sbjct: 737 QPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSV 796 Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 A D + V YSI GD FS+ET G+ + LD+E+ + + L I+A Sbjct: 797 IAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGN----IRIAKPLDHEA-KSQVLLNIQA 851 Query: 770 --ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTD 825 PP++ +V I V DVNDNAP + + + + P A+D D + Sbjct: 852 TLGEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSG 911 Query: 826 KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 ++ Y ++ + L ++ +G + LS L+ + T+ V+ TDG Sbjct: 912 QVTYSLVKESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDG 958 Score = 301 bits (738), Expect = 2e-79 Identities = 272/974 (27%), Positives = 436/974 (44%), Gaps = 81/974 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 ++V D ND+ PVFE +Y +V E S ++ + A+D D G NA + Y I D + Sbjct: 971 VDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNV 1030 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 V F I SG + RA LDRE RY + V ATD +P + Sbjct: 1031 -------TNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAH-- 1081 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + T I V ++D NDN P+F + Y ++E++ V+ + A+D D+G N+AIRY+ Sbjct: 1082 AKTRVI-VRVLDANDNDPKFQKSKYEFRIEENL--RRGSVVGVVTASDLDLGENAAIRYS 1138 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 ++ N+ F + ++G++S + LD E Y LV+ A+D G+P RS + I++ DV Sbjct: 1139 LLPINS--SFQVHPVTGEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDV 1196 Query: 251 NDNAPRFYTSLFQ-ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT-DKDYTGNVDLP 308 NDNAP SV E P G +VRV+A D D G NA +TY++ +D G+ Sbjct: 1197 NDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHG--L 1254 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 +IDP SG + T LD E ++ Y+L V A+DGG+PPR F Sbjct: 1255 FSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTS 1314 Query: 369 GQYEVELAEDEPPG------------TPVVTLTATDADEDNRLHY---EITGGNTRGRFS 413 + ED G VV + ++ ED R+ Y +T F Sbjct: 1315 SSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFD 1374 Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATD----SGGRSDTAMVQINITDANNYAPVF 469 I +G + VA+ LD + + + L + A D + +S V+I + D N+ AP + Sbjct: 1375 IDRHSGN--LVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEW 1432 Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS--NEAVAHHDQQFVIN 527 P V E P+GT + +ATD+D G N + Y L NE+ F ++ Sbjct: 1433 PQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMD 1492 Query: 528 PQTGAITTNKLLDRETMSGYLLTVTARDGG---VPSLSDTTDVEISVVDVNDNEPVF--- 581 TGA++ LD E + YLL V A D L + V + ++D ND+ P F Sbjct: 1493 SLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSP 1552 Query: 582 -KQQLYTANI-MEDAL-VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638 TA++ + DA +G V+ + A D D G NG++ YE+ EG F I+ +G+ Sbjct: 1553 NSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEI-TGGNGEGRFRINSQTGI 1611 Query: 639 IRTNKAL-----DRESVATHDLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCL 692 I K+L D E +L A D G P P+ S++ +H+ ++ +++PP F Sbjct: 1612 IELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVY 1671 Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG---------- 742 I EN P G+ + ++ A NA + Y I G ++ F ++ ++G Sbjct: 1672 RATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITTRGQFDR 1731 Query: 743 SDKAELVTMV---DLDYESPRKKYELVIRAASPPLWN-------DV-RVEILVTDVNDNA 791 +A V V D + +S + + +S + + DV + I V DVNDN+ Sbjct: 1732 ESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNS 1791 Query: 792 PVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSM 849 P + + + G V A D D L Y I GN N ++ ++G + Sbjct: 1792 PEFRPGSCYGLSVPENSEPGVIHTVVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGEL 1851 Query: 850 TLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFL 909 + P L+ T+++ +D ++ + E+ N+ +L+ T Sbjct: 1852 SARP-LDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQE 1910 Query: 910 SPLLGFFIDGLAAI 923 LG + ++A+ Sbjct: 1911 DAPLGTSVVQISAV 1924 Score = 288 bits (706), Expect = 2e-75 Identities = 266/923 (28%), Positives = 427/923 (46%), Gaps = 97/923 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQ--DIGKNAEVEYTIELVTA 67 ++ VLD ND+ P F VRE A+ G V ++ ++ D+ +N+ E +L Sbjct: 1299 RVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVT 1358 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 TLNP ++ F ID SG L+ LDRE + + + ++A D + + Sbjct: 1359 YTLNP--------LTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTAS-N 1409 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 + SS T+ + + D NDN P++ + + V E V +I ATDAD G N + Sbjct: 1410 NPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPV--GTIIHNFTATDADTGTNGDL 1467 Query: 188 RYAIIGGNTQMQ---------FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS--PS 236 +Y +I Q+ F +DSL+G +SL LD+E V+ Y L+++A D S Sbjct: 1468 QYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTE 1527 Query: 237 RSNTT-QLLINIRDVNDNAPRFYT---------SLFQESVSENVPIGYSIVRVQAYDADE 286 R T+ + + I D ND+AP F + SLF +S+ IG + + A D D Sbjct: 1528 RLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLF---ISDATRIGEVVAHIVAVDEDS 1584 Query: 287 GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL-----DRETQAKYQLLVTATDG 341 G N +LTY +T GN + I+ ++G + L D E ++ L++ A D Sbjct: 1585 GDNGQLTYEITG----GNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDH 1640 Query: 342 GDP-PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD--ADEDNR 398 G P P+ ++ F+ Y + E+ P G+ V+ +TA E+ Sbjct: 1641 GQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENAN 1700 Query: 399 LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL------------------- 439 L YEI G F + Q RG+IT D + + YVL Sbjct: 1701 LSYEIPAGVANDLFHVDWQ--RGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVR 1758 Query: 440 ------TVSATDSGGRSDTAMVQINITDANNYAPVFE-NAPYTASVFEDAPIGTTVLVVS 492 ++ T +G D A + I + D N+ +P F + Y SV E++ G VV Sbjct: 1759 KQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGVIHTVV- 1817 Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552 A+D D G NA + YS++ + +F I+ +G ++ + LDRE S Y L + Sbjct: 1818 ASDLDEGPNADLIYSITG-------GNLGNKFSIDSSSGELSA-RPLDREQHSRYTLQIQ 1869 Query: 553 ARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG 611 A D G P S ++ I V D NDN P FK YT ++ EDA +GTSV Q+ A DAD+G Sbjct: 1870 ASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLG 1929 Query: 612 LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT-PPQSST 670 +N R+ Y L + + F ID SG+I T LDRE A+++ +A DGG +S+T Sbjct: 1930 VNARLVYSL--ANETQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSAT 1987 Query: 671 VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD 730 V V I + DIND+ P+FE + G T+ +++A D D G NA + YS+ Sbjct: 1988 VPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNA-- 2045 Query: 731 DSNSFSLETRQGSDKAELVTMVDLDYESPRKKY-ELVIR-AASPPLWNDVRVEILVTDVN 788 ++++ S + R L L ES + + E+V R +PP + +E+L+ + Sbjct: 2046 ENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAP 2105 Query: 789 DNAPVMKDFQIIFN-NYKDCFPVGP-FGRVPAYDAD-VTDKLQYRILSGNNANLILLNET 845 PV++ + K+ P G +V A +D K+Q+ +GN ++ L+ Sbjct: 2106 QGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDGRRQKVQFSFGAGNEDGILSLDSL 2165 Query: 846 TGSMTLSPQLNTNVPKLATMEVS 868 +G + ++ + + +T +S Sbjct: 2166 SGEIRVNKPHLLDYDRFSTPSMS 2188 Score = 287 bits (705), Expect = 2e-75 Identities = 248/842 (29%), Positives = 384/842 (45%), Gaps = 95/842 (11%) Query: 8 HQQIN--VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELV 65 H Q+N V D ND++P FE SV E A G + A D+D G + +V Y++ Sbjct: 861 HTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKE 920 Query: 66 TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125 + L F ID RSG L+ LD E R+T++V ATD P Sbjct: 921 SGKGL-------------------FAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVP 961 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 LS+ TI V++ D NDN P F + Y+V+V E S+ N I ++ A+D D G N+ Sbjct: 962 ---SLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSI--NAQIIQVNASDLDTGNNA 1016 Query: 186 AIRYAII------------GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233 I Y I+ + F I SG + L LD E Y+L + A D G Sbjct: 1017 RITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNG 1076 Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293 +P+ T++++ + D NDN P+F S ++ + EN+ G + V A D D G NA + Sbjct: 1077 TPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIR 1136 Query: 294 YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353 Y++ ++ + P +G + T LDRE + Y L+V A D G P RSA Sbjct: 1137 YSLLP------INSSFQVHPVTGEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVR 1190 Query: 354 XXXXXXXXXXXXFM-PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGG---N 407 P + V + E++PPGT VV + A D D ++ + Y I G + Sbjct: 1191 IHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSD 1250 Query: 408 TRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNY 465 G FSI + G+I LD ++ Y L V+A+D G R M+++ + D N+ Sbjct: 1251 GHGLFSIDPTS--GVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDN 1308 Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATD--SDVGINA--------QITYSLSSEISNE 515 P F ++ V EDA +G V +S + +DV N+ ++TY+L + ++ + Sbjct: 1309 RPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTL-NPLTKD 1367 Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS--LSDTTDVEISVVD 573 + + F I+ +G + +LLDRE S + L + A D + S V+I V D Sbjct: 1368 LI---EAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVAD 1424 Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL--------DPKDR 625 VNDN P + Q + E VGT + ATDAD G NG + Y L + +++ Sbjct: 1425 VNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQ 1484 Query: 626 EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG---TPPQSSTVIVHIKIEDIND 682 F +D +G + LD E+V + L A+D T ++V V ++I D ND Sbjct: 1485 AMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDAND 1544 Query: 683 SPPVFES------DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736 P F S + +IS+ + IG + I A D D G N + Y I GG+ F Sbjct: 1545 HAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFR 1604 Query: 737 LETRQGSDKAELVTMVDLDYESPRK--KYELVIRAAS----PPLWNDVRVEILVTDVNDN 790 + ++ G ELV + E K ++ L+I A P + + + ++V ++N Sbjct: 1605 INSQTGI--IELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNN 1662 Query: 791 AP 792 P Sbjct: 1663 PP 1664 Score = 254 bits (622), Expect = 3e-65 Identities = 269/952 (28%), Positives = 433/952 (45%), Gaps = 110/952 (11%) Query: 10 QINVLDCNDHSP-VFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68 +I+V D ND++P + + Q+ SVRE GT V+ ++A D+D G+NA + Y+I Sbjct: 1190 RIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSI------ 1243 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 + D+ +F ID SG + TR LD E+ + Y + V A+D +P + Sbjct: 1244 -VKGRDSDG---------HGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRE 1293 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD--ADVGANSA 186 + + V ++D NDN P F+ + V ED ++ V+ I + ADV NS Sbjct: 1294 ---TVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAAL--GHVVGSISPIERPADVVRNSV 1348 Query: 187 --------IRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD--GG 233 + Y + + F ID SG++ + + LD E +RL IRA D Sbjct: 1349 EESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTAS 1408 Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293 + +S+ + I + DVNDNAP + VSE P+G I A DAD G N +L Sbjct: 1409 NNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQ 1468 Query: 294 YTMT------DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD--PP 345 Y + ++ + L +D +G + LD E +Y L+V A D Sbjct: 1469 YRLIRYFPQLNESQEQAMSL-FRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTE 1527 Query: 346 RSATA-TXXXXXXXXXXXXXXFM-PGQY-----EVELAEDEPPGTPVVTLTATDADE-DN 397 R T+ T F+ P + +++ G V + A D D DN Sbjct: 1528 RLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDN 1587 Query: 398 -RLHYEITGGNTRGRFSITSQNGR-GLITVAQPL--DFKQERRYVLTVSATDSGG---RS 450 +L YEITGGN GRF I SQ G L+ P D ++ R+ L + A D G + Sbjct: 1588 GQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKK 1647 Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510 + + + + ++N P F A Y A++ E+ P G+ VL V+A NA ++Y + + Sbjct: 1648 SSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPA 1707 Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG------------- 557 ++N+ F ++ Q G ITT DRE+ + Y+L V RD Sbjct: 1708 GVANDL-------FHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQ 1760 Query: 558 --VPSLSDTTD--------VEISVVDVNDNEPVFKQ-QLYTANIMEDALVGTSVSQVGAT 606 S+ DT++ + I+V DVNDN P F+ Y ++ E++ G + V A+ Sbjct: 1761 RSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGV-IHTVVAS 1819 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D D G N + Y + + F ID +SG + + LDRE + + L+ A D G P Sbjct: 1820 DLDEGPNADLIYSITGGNLGN-KFSIDSSSGELSA-RPLDREQHSRYTLQIQASDRGQPK 1877 Query: 667 -QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 + + I +ED ND+ P F+ T + E++P+GT++ +I A D D G NA + YS Sbjct: 1878 SRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYS 1937 Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN----DVRVE 781 + + F+++ + G + T+ LD E + Y ++ A + V V+ Sbjct: 1938 L-ANETQWQFAIDGQSGL----ITTVGKLDREL-QASYNFMVLATDGGRYEVRSATVPVQ 1991 Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNA-- 837 I V D+NDN P+ + + I P +V A DAD+ ++ Y + + N+A Sbjct: 1992 INVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVS 2051 Query: 838 NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889 +N +TG+++ S L + KL +EV D N ++ + L LI E Sbjct: 2052 AKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGE 2103 Score = 221 bits (540), Expect = 2e-55 Identities = 205/689 (29%), Positives = 314/689 (45%), Gaps = 72/689 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ +LD NDH+P F V +S G T + IG E +V D Sbjct: 1536 RLRILDANDHAPHF--------VSPNSSGGKTASLFISDATRIG-----EVVAHIVAVDE 1582 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-----LTRASLDREKVARYTVLVKATDQAS 124 + ++ + FRI+ ++G + L A+ D EK R+ +++ A D Sbjct: 1583 DSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQ 1642 Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184 P + S+ +H+ + ++N P+F + Y ++ E+ V + ++ A N Sbjct: 1643 PEPKK--SSLNLHLIVQGSHNNPPRFLQAVYRATILEN--VPSGSFVLQVTAKSLHGAEN 1698 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-------- 236 + + Y I G F +D G ++ D E SY L + +D S Sbjct: 1699 ANLSYEIPAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVR 1758 Query: 237 --RSNTT-------------QLLINIRDVNDNAPRFYT-SLFQESVSENVPIGYSIVRVQ 280 RS+ + + I + DVNDN+P F S + SV EN G I V Sbjct: 1759 KQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGV-IHTVV 1817 Query: 281 AYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD 340 A D DEG NA+L Y++T GN+ +ID SG + ++ LDRE ++Y L + A+D Sbjct: 1818 ASDLDEGPNADLIYSITG----GNLGNKFSIDSSSGEL-SARPLDREQHSRYTLQIQASD 1872 Query: 341 GGDP-PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDN 397 G P R F +Y + ED P GT VV ++A DAD + Sbjct: 1873 RGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNA 1932 Query: 398 RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAM 454 RL Y + T+ +F+I Q+ GLIT LD + + Y V ATD G RS T Sbjct: 1933 RLVYSL-ANETQWQFAIDGQS--GLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVP 1989 Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 VQIN+ D N+ P+FE PY V G T+L V A D+D+G NA+I YSL++E N Sbjct: 1990 VQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAE--N 2047 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 AV+ +F INP TGA++ ++ L E+ L V ARD G P S +E+ + + Sbjct: 2048 SAVS---AKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEA 2104 Query: 575 NDNEPV--FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632 PV F+ + Y + E++ GT + QV A +D G ++ + E+G + Sbjct: 2105 PQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSD-GRRQKVQFSFG-AGNEDGILSL 2162 Query: 633 DPASGVIRTNK--ALDRESVATHDLKAVA 659 D SG IR NK LD + +T + A++ Sbjct: 2163 DSLSGEIRVNKPHLLDYDRFSTPSMSALS 2191 Score = 217 bits (531), Expect = 3e-54 Identities = 208/750 (27%), Positives = 334/750 (44%), Gaps = 83/750 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D ND+SP F +Q+ A+V EG + GT V + A D D G NA + Y I D Sbjct: 2257 IELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHI----VDG- 2311 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N ++A ++ F SG + T LDRE Y + + ATD+ P ++ Sbjct: 2312 NHDNAFV--------IEPAF-----SGIVRTNIVLDREIRDIYKLKIIATDEGVP---QM 2355 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY- 189 + TATI V I+D NDN P F V+V E + VI I A D D R Sbjct: 2356 TGTATIRVQIVDVNDNQPTFPPNN-LVTVSEATEL--GAVITSISANDVDTYPALTYRLG 2412 Query: 190 --AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 + + F++D SG + L + LDYE + Y L + A D +R T L + + Sbjct: 2413 AESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEAR---TVLTVRV 2469 Query: 248 RDVNDNAPRF-------YTSLFQ--ESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMT 297 D NDNAP F Y ++ +SE++ + + ++ V A DAD EG N+++ Y + Sbjct: 2470 NDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIY-II 2528 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSG---QLDRETQAKYQLLVTATDGGDPPRSATATXXX 354 + G ++ P +G V + Q + Y + + A D G P ++ Sbjct: 2529 EPAQEG-----FSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRV 2583 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSI 414 F+ QY +++E P G+ V+ L D+ I GN F + Sbjct: 2584 QANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQS----LAIIAGNEESAFEL 2639 Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--------RSDTAMVQINITDANNYA 466 I + +PLD ++ Y L + + G S V I I DAN+ Sbjct: 2640 LQSKA---IVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNF 2696 Query: 467 PVFE-NAPYTASVFEDAPIGTTVLVVSATDSDV--GINAQITYSLSSEISNEAVAHHDQQ 523 P+F+ +A Y A + E AP+ ++ + A D+D N+++ Y ++S + + Sbjct: 2697 PIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITS-------GNDEHM 2749 Query: 524 FVINPQTGAITTNKLLDRET-MSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEPVF 581 F I+ TG + N LD ++ Y L + A D L + + D NDNEP F Sbjct: 2750 FTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKF 2809 Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS---FVIDPASGV 638 Y + E+ VG+SV + A+D D G G+++Y + P +E S F +D SG+ Sbjct: 2810 PLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGL 2869 Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI-- 696 + + D E +D++ +A D G + ++V V ++IE ++ P F F + Sbjct: 2870 VTSAFVFDYEQRQRYDMELLASDMG--GKKASVAVRVEIESRDEFTPQFTERTYRFVLPA 2927 Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 + P G +G++ A D D GP+ V Y + Sbjct: 2928 AVALPQGYVVGQVTATDSDSGPDGRVVYQL 2957 Score = 201 bits (490), Expect = 3e-49 Identities = 178/569 (31%), Positives = 266/569 (46%), Gaps = 67/569 (11%) Query: 17 NDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAX 76 +++ P F Y A++ E SG+ VL + A +NA + Y I A+ Sbjct: 1660 HNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVAN-------- 1711 Query: 77 XXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD-------QASPV--- 126 D+F +D + G + TR DRE A Y + V D +S V Sbjct: 1712 -----------DLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQ 1760 Query: 127 --SDRLSST--------ATIHVNIIDDNDNYPQFSEKT-YTVSVDEDISVTDNPVIAKIK 175 SD + T ATI++ + D NDN P+F + Y +SV E+ ++ VI + Sbjct: 1761 RSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPEN---SEPGVIHTVV 1817 Query: 176 ATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP 235 A+D D G N+ + Y+I GGN +FSIDS SG++S + LD EQ Y L I+A D G P Sbjct: 1818 ASDLDEGPNADLIYSITGGNLGNKFSIDSSSGELS-ARPLDREQHSRYTLQIQASDRGQP 1876 Query: 236 -SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294 SR + I + D NDNAPRF S + SV E+ P+G S+V++ A DAD GVNA L Y Sbjct: 1877 KSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVY 1936 Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD-PPRSATATXX 353 ++ ++ ID +SG + T G+LDRE QA Y +V ATDGG RSAT Sbjct: 1937 SLANE-----TQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQ 1991 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGR 411 F Y ++ PG ++ + A DAD + + Y + N+ Sbjct: 1992 INVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVS 2051 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPV- 468 G ++ +Q L + + L V A D G +S ++++ I +A PV Sbjct: 2052 AKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVL 2111 Query: 469 -FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527 F+N Y + E++P GT +L V A SD G ++ +S + NE D ++ Sbjct: 2112 RFQNETYRVMLKENSPSGTRLLQVVALRSD-GRRQKVQFSFGA--GNE-----DGILSLD 2163 Query: 528 PQTGAITTNK--LLDRETMSGYLLTVTAR 554 +G I NK LLD + S ++ +R Sbjct: 2164 SLSGEIRVNKPHLLDYDRFSTPSMSALSR 2192 Score = 198 bits (484), Expect = 1e-48 Identities = 180/608 (29%), Positives = 282/608 (46%), Gaps = 57/608 (9%) Query: 215 LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY 274 L Q R+V+ A+ +P ++ +L+I + D NDN+P+F F +VSE G Sbjct: 2227 LTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGT 2286 Query: 275 SIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR-SGWVYTSGQLDRETQAKYQ 333 + +V A+D+D G NA L Y + D GN D I+P SG V T+ LDRE + Y+ Sbjct: 2287 FVAQVHAFDSDAGSNARLRYHIVD----GNHDNAFVIEPAFSGIVRTNIVLDREIRDIYK 2342 Query: 334 LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393 L + ATD G P + TAT F P V ++E G + +++A D Sbjct: 2343 LKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNL-VTVSEATELGAVITSISANDV 2401 Query: 394 DEDNRLHYEITGGNTRG--RFSITS-QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS 450 D L Y + +T SI + G + + + LD++ ++ Y L V A+D+ + Sbjct: 2402 DTYPALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEA 2461 Query: 451 DTAMVQINITDANNYAPV---------FENAPYTASVFEDAPIGTTVLVVSATDSD-VGI 500 T + + + D N+ APV F P + + E + +L V+ATD+D G Sbjct: 2462 RTVLT-VRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGN 2520 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN--KLLDRETMSG-YLLTVTARDGG 557 N+++ Y + E + E F ++P G ++ N +L + SG Y + + A+D G Sbjct: 2521 NSKVIYII--EPAQEG-------FSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAG 2571 Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617 P+L +T + + D F Q Y A I E A +G+ V Q+G D L Sbjct: 2572 KPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQSL----- 2626 Query: 618 YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP------QSSTV 671 EE +F + + ++ K LDRE + L+ V PP SS + Sbjct: 2627 --AIIAGNEESAFELLQSKAIVLV-KPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGI 2683 Query: 672 IVHIKIEDINDSPPVFE-SDCLTFYISENSPIGTTIGEIRAHDPDE--GPNAVVHYSIKG 728 V I I D ND+ P+F+ S ISE +P+ +I +++A D D+ PN+ V Y I Sbjct: 2684 SVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITS 2743 Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP----PLWNDVRVEILV 784 G+D + F+++ G L LDY+S K YEL+IRA PL + + + Sbjct: 2744 GNDEHMFTIDLVTG----VLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLEL 2799 Query: 785 TDVNDNAP 792 D NDN P Sbjct: 2800 HDENDNEP 2807 Score = 196 bits (477), Expect = 1e-47 Identities = 190/665 (28%), Positives = 301/665 (45%), Gaps = 46/665 (6%) Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L+S A + + + D+NDN P+FS+K + +V E + +A++ A D+D G+N+ +RY Sbjct: 2249 LASYAELVIELEDENDNSPKFSQKQFVATVSEGNN--KGTFVAQVHAFDSDAGSNARLRY 2306 Query: 190 AIIGGNTQMQFSID-SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 I+ GN F I+ + SG V LD E Y+L I A D G P + T + + I Sbjct: 2307 HIVDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIV 2366 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 DVNDN P F + +VSE +G I + A D D LTY + + ++ Sbjct: 2367 DVNDNQPTFPPNNLV-TVSEATELGAVITSISANDVD--TYPALTYRLGAESTVDIENMS 2423 Query: 309 I-TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 I +D SG + +LD E Q +Y+L V A+D R+ Sbjct: 2424 IFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEARTVLTVRVNDENDNAPVFLAQQ 2483 Query: 368 PGQYEV------ELAEDEPPGTPVVTLTATDAD-EDNRLHYEITGGNTRGRFSITSQNGR 420 P Y E++E ++T+ ATDAD E N + FS+ NG Sbjct: 2484 PPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNGV 2543 Query: 421 GLITVA--QPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTA 476 + ++ QP Y + + A D+G + ++++ D + F Y A Sbjct: 2544 VSVNMSRLQPA-VSSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRA 2602 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 + E AP+G+ VL +G +A + SL+ NE A F + Q+ AI Sbjct: 2603 QISEAAPLGSVVL-------QLGQDA-LDQSLAIIAGNEESA-----FELL-QSKAIVLV 2648 Query: 537 KLLDRETMSGYLLT-VTARDGGVPSLSDTTD-----VEISVVDVNDNEPVFKQQL-YTAN 589 K LDRE Y L V + G P +S V I+++D NDN P+F + Y A Sbjct: 2649 KPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAE 2708 Query: 590 IMEDALVGTSVSQVGATDADVGL--NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647 I E A + S++Q+ A DAD N + Y++ +E F ID +GV+ N LD Sbjct: 2709 ISELAPLRYSIAQLQAIDADQENTPNSEVVYDIT-SGNDEHMFTIDLVTGVLFVNNRLDY 2767 Query: 648 ESVA-THDLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 +S A +++L A D P S +++ D ND+ P F +++EN P+G++ Sbjct: 2768 DSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSS 2827 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765 + A D D+GP ++YSI S R S+ + + DYE R++Y++ Sbjct: 2828 VFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQ-RQRYDM 2886 Query: 766 VIRAA 770 + A+ Sbjct: 2887 ELLAS 2891 Score = 142 bits (345), Expect = 9e-32 Identities = 177/697 (25%), Positives = 300/697 (43%), Gaps = 61/697 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D ND++PVF QQ A + +I ++ V++ + V A Sbjct: 2467 VRVNDENDNAPVFLAQQPPA-----------YFAILPAISEISESLSVDFDLLTVNATDA 2515 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR---YTVLVKATDQASPVS 127 + E Q+ F + +G + S + V+ Y V + A D P Sbjct: 2516 DSEGNNSKVIYIIEPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPA- 2574 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 L S+ + V D+ QF + Y + E + V+ ++ D Sbjct: 2575 --LKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPL--GSVVLQLGQDALDQSL---- 2626 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRL-VIRAQDGGSP-----SRSNTT 241 AII GN + F + S + LVK LD E+ Y+L ++ + G P + S+ Sbjct: 2627 --AIIAGNEESAFELLQ-SKAIVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGI 2683 Query: 242 QLLINIRDVNDNAPRFYTSL-FQESVSENVPIGYSIVRVQAYDADEG--VNAELTYTMTD 298 ++I I D NDN P F S ++ +SE P+ YSI ++QA DAD+ N+E+ Y +T Sbjct: 2684 SVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDIT- 2742 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDP-PRSATATXXXXX 356 +GN + TID +G ++ + +LD ++ AK Y+L++ A D P + Sbjct: 2743 ---SGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLEL 2799 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEI----TGGNTRG 410 F +Y LAE+EP G+ V A+D D+ +L+Y I + ++ Sbjct: 2800 HDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWK 2859 Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFE 470 F + S++G L+T A D++Q +RY + + A+D GG+ + V++ I + + P F Sbjct: 2860 MFRVDSESG--LVTSAFVFDYEQRQRYDMELLASDMGGKKASVAVRVEIESRDEFTPQFT 2917 Query: 471 NAPY--TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528 Y P G V V+ATDSD G + ++ Y LS+ S+ V +I Sbjct: 2918 ERTYRFVLPAAVALPQGYVVGQVTATDSDSGPDGRVVYQLSAPHSHFKVNRSSGAVLIKR 2977 Query: 529 Q---TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV-NDNEPVFKQQ 584 + G N +D +S L ++A G SLS VEI++ + + + Sbjct: 2978 KLKLDGDGDGNLYMDGRDIS---LVISASSGRHNSLSSMAVVEIALDPLAHPGTNLASAG 3034 Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHY-ELDPKDREEGSFVIDPASGVIRTNK 643 ++ + D +G V+ + A G+ IH P++ + D A GV TN Sbjct: 3035 GSSSGSIGDWAIGLLVAFLLVLCAAAGIFLFIHMRSRKPRNAVKPHLATDNA-GVGNTNS 3093 Query: 644 ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680 +D + T ++ +I GG +S K ++I Sbjct: 3094 YVDPSAFDTIPIRG-SISGGAAGAASGQFAPPKYDEI 3129 Score = 132 bits (318), Expect = 2e-28 Identities = 83/246 (33%), Positives = 125/246 (50%), Gaps = 5/246 (2%) Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 + + AR P L+ ++ I + D NDN P F Q+ + A + E GT V+QV A D+ Sbjct: 2237 VVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDS 2296 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPA-SGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 D G N R+ Y + + +FVI+PA SG++RTN LDRE + LK +A D G P Sbjct: 2297 DAGSNARLRYHI-VDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQM 2355 Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 + T + ++I D+ND+ P F + L +SE + +G I I A+D D P + Sbjct: 2356 TGTATIRVQIVDVNDNQPTFPPNNLV-TVSEATELGAVITSISANDVDTYPALTYRLGAE 2414 Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDV 787 D + S+ +LV LDYE +++YEL + A+ + + V D Sbjct: 2415 STVDIENMSIFALD-RYSGKLVLKRRLDYEL-QQEYELDVIASDAAHEARTVLTVRVNDE 2472 Query: 788 NDNAPV 793 NDNAPV Sbjct: 2473 NDNAPV 2478 Score = 116 bits (280), Expect = 7e-24 Identities = 131/519 (25%), Positives = 228/519 (43%), Gaps = 49/519 (9%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLI 423 F Q+ ++E GT V + A D+D + RL Y I GN F I G++ Sbjct: 2269 FSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDNAFVIEPAFS-GIV 2327 Query: 424 TVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 LD + Y L + ATD G + TA +++ I D N+ P F +V E Sbjct: 2328 RTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFP-PNNLVTVSEA 2386 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 +G + +SA D D +TY L +E + + + F ++ +G + + LD Sbjct: 2387 TELGAVITSISANDVDT--YPALTYRLGAESTVDI--ENMSIFALDRYSGKLVLKRRLDY 2442 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ---LYTA------NIME 592 E Y L V A D + T + + V D NDN PVF Q Y A I E Sbjct: 2443 ELQQEYELDVIASDAAHEA---RTVLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISE 2499 Query: 593 DALVGTSVSQVGATDADV-GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA 651 V + V ATDAD G N ++ Y ++P +EG F + P++GV+ N + + +V+ Sbjct: 2500 SLSVDFDLLTVNATDADSEGNNSKVIYIIEPA--QEG-FSVHPSNGVVSVNMSRLQPAVS 2556 Query: 652 T---HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 + + ++ +A D G P S+ ++ ++ D F + ISE +P+G+ + + Sbjct: 2557 SSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQ 2616 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768 + D+ +I G++ ++F L S LV +D + K ++ Sbjct: 2617 LGQDALDQS------LAIIAGNEESAFELLQ---SKAIVLVKPLDRERNDLYKLRLVLSH 2667 Query: 769 AASPPLWNDVR----VEILVT--DVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDA 821 PPL + + + +++T D NDN P+ + P+ ++ A DA Sbjct: 2668 PHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDA 2727 Query: 822 DVTD----KLQYRILSGNNANLILLNETTGSMTLSPQLN 856 D + ++ Y I SGN+ ++ ++ TG + ++ +L+ Sbjct: 2728 DQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLD 2766 Score = 74.5 bits (175), Expect = 4e-11 Identities = 77/297 (25%), Positives = 131/297 (44%), Gaps = 20/297 (6%) Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 Q+G G++ Y + + E ID A+G IRT LDRE+ A++ L A+ + Sbjct: 42 QIGYIGDFGGIDSGPPYIIVAEAGVETDLAIDRATGEIRTKVKLDRETRASYSLVAIPLS 101 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 G + V + ++D ND+ P F + EN+P + A D D P Sbjct: 102 G------RNIRVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNT 155 Query: 722 VHYSIKGGDDSNSFSLET---RQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLW 775 Y+I G+ +++F L + R G +L LD E+ Y L+I A +PPL Sbjct: 156 QRYNIVSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRET-TPGYSLLIEALDGGTPPLR 214 Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDK--LQYRI- 831 + V I + DVNDN P+ + F + VG +V A D D + ++Y I Sbjct: 215 GFMTVNITIQDVNDNQPIFNQSR-YFATVPENATVGTSVLQVYASDTDADENGLVEYAIN 273 Query: 832 -LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRL 886 + + ++ TG++ ++ L+ +L + V D G ++ +S+R+ Sbjct: 274 RRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRV 330 Score = 36.7 bits (81), Expect = 9.2 Identities = 38/165 (23%), Positives = 74/165 (44%), Gaps = 8/165 (4%) Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIRAASPP-LWNDVRVEILVTDV 787 D+S+ S +A + L P + + LV R A P L + + I + D Sbjct: 2203 DESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDE 2262 Query: 788 NDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTD--KLQYRILSGNNANLILLNE 844 NDN+P Q + + G F +V A+D+D +L+Y I+ GN+ N ++ Sbjct: 2263 NDNSPKFSQKQFVAT-VSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDNAFVIEP 2321 Query: 845 T-TGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLI 887 +G + + L+ + + +++ TD GV ++ + V+++ Sbjct: 2322 AFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIV 2366 >UniRef50_A7RQ19 Cluster: Predicted protein; n=5; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 3766 Score = 356 bits (875), Expect = 6e-96 Identities = 408/1561 (26%), Positives = 652/1561 (41%), Gaps = 177/1561 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D ND P F++ Y+A VRE A GTTV+T+KATD+D G V Y ++ + Sbjct: 1810 ITLEDVNDDKPTFDLGNYDARVRENAPIGTTVITIKATDRDTGDAGVVTYFLKAGS---- 1865 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F ID SG L T+ S DRE + ++V+V A D+ + L Sbjct: 1866 ----------------DEHFAIDVNSGTLTTKKSFDREGQSLFSVIVIARDKGNNPG-AL 1908 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S + V ++D+ND+ PQF + + SV E S T I ++ ATD D+G N+ + Y Sbjct: 1909 SEEVAVKVLVVDENDSPPQFDQAEFQTSVSE--SATIGTSILEVVATDQDIGDNAKLEYF 1966 Query: 191 IIGGNTQMQFSIDSLS------GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 I GG+ + F++ ++S G+V + LD+E SY + + A DG S TT++L Sbjct: 1967 ISGGDGRFWFAVQTISKSGRTYGEVQVDARLDFETKSSYTIDVTATDGRF---SATTRVL 2023 Query: 245 INIRDVNDNAPRFYT--------SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 I I D ND P F T ++ VSE G +++V A D D + + YT+ Sbjct: 2024 ITITDANDIVPMFMTLTTPTLLSPIYTGRVSEMTGSGVEVLKVYAVDTD---SPNIQYTL 2080 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATDGGDPPRSATATXXXX 355 + G + T Q LDRE + V A DG + +A Sbjct: 2081 EGSSSYFTIAARQEGGKFVGIISTGSQPLDREATPIFSFNVLAKDG---VHTGSAYIEIN 2137 Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-----DNRLHYEITGGNTRG 410 F Y + E++ GT V+ + A D D+ + + Y +T N G Sbjct: 2138 VTDINDNQPRFPNSLYVGYVEENKAAGTSVMYVQAHDDDDPYLGGNAEIRYTLTD-NAGG 2196 Query: 411 RFSITSQNGRGLITVAQPLDFKQE-RRYVLTVSATDSGGR--SDTAMVQINITDANNYAP 467 +F I + L+T + LD + + +TV ATD G S T + I +TDAN++AP Sbjct: 2197 KFKIDANTA--LVTTEEILDRETSPNSFTITVLATDQGANKLSTTKVATIYVTDANDHAP 2254 Query: 468 VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527 VF + +V ED G V VSATD+D G NA++ + ++ NE A F ++ Sbjct: 2255 VFTKRIFRGTVSEDVRPGYVVTSVSATDTDTGPNAELEFVVTH--GNEPAA-----FYVD 2307 Query: 528 PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD--VEISVVDVNDNEPVFKQQL 585 P G + + +L+ Y LTVT D G+P LSD + V I++ D NDN P+F Sbjct: 2308 PSKGTVHVSGILNYTLRKSYNLTVTVSDRGMPVLSDNSPAYVLITITDANDNAPIFIPNQ 2367 Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL---DPKDREEGSFVIDPAS-GVIRT 641 Y + ED VG+ V V A D D G N + +++ +P D E D +S G++RT Sbjct: 2368 YNKTVAEDLAVGSPVVVVTAVDYDSGDNAKFVFDITGGNPDDLFEVVPNPDNSSLGIVRT 2427 Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701 LDRE+ H L+ A D G + V + + D+ND+ P F+ I EN Sbjct: 2428 RLPLDRETTPIHHLEITAKDTGG--LTGKAHVWLTLLDVNDNGPWFQPPFFVGKIKENVN 2485 Query: 702 IGTTIGEIRAHDPDEGPN-AVVHYSIKGGDDSNSFSLETRQGSD-KAELVTMVDLDYESP 759 + + ++ A+DPD N A Y+I G S +F+ + ++ ++ + D E+ Sbjct: 2486 VKQFVTKVSANDPDTKNNGAPFTYAIYNGTVSGNFAFDIATITNVTTDMSSSGTFDRET- 2544 Query: 760 RKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRV 816 + + I P N V + V D NDN P II N+Y F GP + Sbjct: 2545 MTTWTIGIAGTDSGRPAKSNFTYVYVDVQDDNDNEPYDGRMTIIVNSYNGKFRGGPIAKT 2604 Query: 817 PAYDADVT-DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG--- 872 DAD D Y + S N ++ TTG ++ + + L V G Sbjct: 2605 YYRDADYDGDVNTYTLQSQTGGNFFTVDTTTGEISAAKDIPVGEYSLVISVTEVNTGNPP 2664 Query: 873 -VNEIK------AMMQLSVRLITEEMLLNSITVRLNDM-TAEQFLSPLLGFFIDGLAAII 924 NE+ + + VR IT + + NS+ ++++DM E F+ + L+ + Sbjct: 2665 RANEVNFPKTVTSRATVIVRDITSKAVSNSVALQISDMRKVEYFVGDYHDVVVGELSRMF 2724 Query: 925 PCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRT 984 I +FSVQ + + L+V F+ + E + P + V +R Sbjct: 2725 GVSSSGIEVFSVQ-PSPIKVMALDVQFAVKTGSDE---------YTKPYDVIRVVTDNRE 2774 Query: 985 TLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTC 1044 L L ++V ++C E +C+ V++ +A + D + P +S T Sbjct: 2775 RLTNLG-LKVTSIGIDMCALER-ERVGKCINVVETSSAYKIASGD--YGKVPAPASSITL 2830 Query: 1045 QCPEGFTGVNCETILTKA-SCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVC 1103 + TI+ +C + C +G C G + C Y C Sbjct: 2831 VSMDVVLRDKYVTIIEPGKNCSNENP---CLNGGTCHDTVPAG--WRVCQCPRGYRGPHC 2885 Query: 1104 ELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRY-----NERHDFLAL- 1157 E R+F +S++ P L L +F T+ GL+LY G N DFL + Sbjct: 2886 EQTTRTFRGTSYIWLPKLTAYDIRELSFEFTTEFKDGLMLYQGPLKPGDNNGAKDFLPVF 2945 Query: 1158 ------ELVSSEAGRGGGPGLRFSFSLGG-------GKSEITV----EGNVGDGSWHTVE 1200 + +E ++ G G IT+ N+ D WHTV+ Sbjct: 2946 PNLSIFQATITETITVPRTSWQYFLDEGHLVVRVSLGYEPITINMTRRPNLNDKEWHTVQ 3005 Query: 1201 I--EYFNR-TITMILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLD 1257 I + +R I +I+D C + K T +V +L+ Sbjct: 3006 IIRDVIDRKMIRVIIDRCQSAQIVEENGRVFEKRDTCEITGRVKGRSV---------YLN 3056 Query: 1258 LTGPLQIGGLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRC 1317 GPLQIGG+ + + F GCI + K DL + + GC + Sbjct: 3057 GFGPLQIGGVETDLTFIGITTTGFRGCIRNIIDTEKMYDLRNPIKVVNAPEGCTLAGTCP 3116 Query: 1318 SSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPW-------RFGGDGMLSFNPLL 1370 ++ E S + +C C G+TG+ C D + + +F G+ + L+ Sbjct: 3117 NNCNDKGYCEPSLMAGKSMCVCDLGYTGRACNDRSEANYYLENSFSQFLLTGIRARRELI 3176 Query: 1371 RPIQLPWLNA------LSIR----TRQRDAFVMS---------IQLKSGLLHYSYN-GET 1410 +P +P +N L ++ T+ F+ S + +K +L Y + G+ Sbjct: 3177 QP-PVPLMNEYYTHINLQVKLDPGTKDCVLFLSSNSLGTEFNRLDVKDHMLRYIFRLGDR 3235 Query: 1411 M---YLPMATLSDGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIGG 1467 M +P +SDG +H + + G + +DY + K+ G I GG Sbjct: 3236 MKVLSIPQYNISDGKYHSVMVNREGNYAEMQIDYRAKMAGTTGGVQKLLNMGGGSIFTGG 3295 Query: 1468 L 1468 L Sbjct: 3296 L 3296 Score = 277 bits (679), Expect = 3e-72 Identities = 231/823 (28%), Positives = 377/823 (45%), Gaps = 48/823 (5%) Query: 86 VQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145 + + F ++ +G + T + LD E+++ K +A + L ST ++ + + D ND Sbjct: 1759 IDEKFSVE-TNGQIKTASQLDYEQLSPGDKTFKLQVRAQEENTNLYSTCSVAITLEDVND 1817 Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205 + P F Y V E+ + + IKATD D G + Y + G+ + F+ID Sbjct: 1818 DKPTFDLGNYDARVRENAPI--GTTVITIKATDRDTGDAGVVTYFLKAGSDE-HFAIDVN 1874 Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQD-GGSPSR-SNTTQLLINIRDVNDNAPRFYTSLFQ 263 SG ++ K+ D E + +++ A+D G +P S + + + D ND+ P+F + FQ Sbjct: 1875 SGTLTTKKSFDREGQSLFSVIVIARDKGNNPGALSEEVAVKVLVVDENDSPPQFDQAEFQ 1934 Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY---- 319 SVSE+ IG SI+ V A D D G NA+L Y ++ D G + +SG Y Sbjct: 1935 TSVSESATIGTSILEVVATDQDIGDNAKLEYFISGGD--GRFWFAVQTISKSGRTYGEVQ 1992 Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRSA-----TATXXXXXXXXXXXXXXFMPGQYEVE 374 +LD ET++ Y + VTATDG + T + Y Sbjct: 1993 VDARLDFETKSSYTIDVTATDGRFSATTRVLITITDANDIVPMFMTLTTPTLLSPIYTGR 2052 Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR--GLI-TVAQPLDF 431 ++E G V+ + A D D N + Y + G ++ + + G+ G+I T +QPLD Sbjct: 2053 VSEMTGSGVEVLKVYAVDTDSPN-IQYTLEGSSSYFTIAARQEGGKFVGIISTGSQPLDR 2111 Query: 432 KQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491 + + V A D G + +A ++IN+TD N+ P F N+ Y V E+ GT+V+ V Sbjct: 2112 EATPIFSFNVLAKD-GVHTGSAYIEINVTDINDNQPRFPNSLYVGYVEENKAAGTSVMYV 2170 Query: 492 SATDSD---VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM-SGY 547 A D D +G NA+I Y+L+ + F I+ T +TT ++LDRET + + Sbjct: 2171 QAHDDDDPYLGGNAEIRYTLTDNAGGK--------FKIDANTALVTTEEILDRETSPNSF 2222 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 +TV A D G LS T I V D ND+ PVF ++++ + ED G V+ V ATD Sbjct: 2223 TITVLATDQGANKLSTTKVATIYVTDANDHAPVFTKRIFRGTVSEDVRPGYVVTSVSATD 2282 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 D G N + + + E +F +DP+ G + + L+ +++L D G P Sbjct: 2283 TDTGPNAELEFVVT-HGNEPAAFYVDPSKGTVHVSGILNYTLRKSYNLTVTVSDRGMPVL 2341 Query: 668 S--STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 S S V I I D ND+ P+F + ++E+ +G+ + + A D D G NA + Sbjct: 2342 SDNSPAYVLITITDANDNAPIFIPNQYNKTVAEDLAVGSPVVVVTAVDYDSGDNAKFVFD 2401 Query: 726 IKGGDDSNSFSLETRQGSDKAELV-TMVDLDYESPRKKYELVIRAASPPLWNDVRVEILV 784 I GG+ + F + + +V T + LD E+ + + + L V + + Sbjct: 2402 ITGGNPDDLFEVVPNPDNSSLGIVRTRLPLDRETTPIHHLEITAKDTGGLTGKAHVWLTL 2461 Query: 785 TDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDK---LQYRI----LSGNN 836 DVNDN P + K+ V F +V A D D + Y I +SGN Sbjct: 2462 LDVNDNGPWFQP-PFFVGKIKENVNVKQFVTKVSANDPDTKNNGAPFTYAIYNGTVSGNF 2520 Query: 837 A-NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKA 878 A ++ + T M+ S + T+ ++ TD K+ Sbjct: 2521 AFDIATITNVTTDMSSSGTFDRETMTTWTIGIAGTDSGRPAKS 2563 Score = 265 bits (649), Expect = 1e-68 Identities = 242/814 (29%), Positives = 369/814 (45%), Gaps = 90/814 (11%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ V+D ND P F+ +++ SV E A+ GT++L + ATDQDIG NA++EY I Sbjct: 1915 KVLVVDENDSPPQFDQAEFQTSVSESATIGTSILEVVATDQDIGDNAKLEYFI------- 1967 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 VQ + + G + A LD E + YT+ V ATD R Sbjct: 1968 ------SGGDGRFWFAVQTISKSGRTYGEVQVDARLDFETKSSYTIDVTATD------GR 2015 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKT--------YTVSVDEDISVTDNPV-IAKIKATDAD 180 S+T + + I D ND P F T YT V E +T + V + K+ A D D Sbjct: 2016 FSATTRVLITITDANDIVPMFMTLTTPTLLSPIYTGRVSE---MTGSGVEVLKVYAVDTD 2072 Query: 181 VGANSAIRYAIIGGNTQMQFSIDSLSGD-VSLVKT----LDYEQVRSYRLVIRAQDGGSP 235 + I+Y + G ++ + G V ++ T LD E + + A+DG Sbjct: 2073 ---SPNIQYTLEGSSSYFTIAARQEGGKFVGIISTGSQPLDREATPIFSFNVLAKDG--- 2126 Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE---GVNAEL 292 + + + IN+ D+NDN PRF SL+ V EN G S++ VQA+D D+ G NAE+ Sbjct: 2127 VHTGSAYIEINVTDINDNQPRFPNSLYVGYVEENKAAGTSVMYVQAHDDDDPYLGGNAEI 2186 Query: 293 TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA-KYQLLVTATDGGDPPRSATAT 351 YT+TD N ID + V T LDRET + + V ATD G S T Sbjct: 2187 RYTLTD-----NAGGKFKIDANTALVTTEEILDRETSPNSFTITVLATDQGANKLSTTKV 2241 Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTR 409 F + ++ED PG V +++ATD D + L + +T GN Sbjct: 2242 ATIYVTDANDHAPVFTKRIFRGTVSEDVRPGYVVTSVSATDTDTGPNAELEFVVTHGNEP 2301 Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNY 465 F + +G + V+ L++ + Y LTV+ +D G + A V I ITDAN+ Sbjct: 2302 AAFYV--DPSKGTVHVSGILNYTLRKSYNLTVTVSDRGMPVLSDNSPAYVLITITDANDN 2359 Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN---EAVAHHDQ 522 AP+F Y +V ED +G+ V+VV+A D D G NA+ + ++ + E V + D Sbjct: 2360 APIFIPNQYNKTVAEDLAVGSPVVVVTAVDYDSGDNAKFVFDITGGNPDDLFEVVPNPD- 2418 Query: 523 QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582 N G + T LDRET + L +TA+D G L+ V ++++DVNDN P F+ Sbjct: 2419 ----NSSLGIVRTRLPLDRETTPIHHLEITAKDTG--GLTGKAHVWLTLLDVNDNGPWFQ 2472 Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV---- 638 + I E+ V V++V A D D NG G+F D A+ Sbjct: 2473 PPFFVGKIKENVNVKQFVTKVSANDPDTKNNGAPFTYAIYNGTVSGNFAFDIATITNVTT 2532 Query: 639 -IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697 + ++ DRE++ T + D G P +S+ V++ ++D ND+ P ++ S Sbjct: 2533 DMSSSGTFDRETMTTWTIGIAGTDSGRPAKSNFTYVYVDVQDDNDNEP-YDGRMTIIVNS 2591 Query: 698 ENSPI-GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756 N G I + D D + V Y+++ N F+++T G E+ D+ Sbjct: 2592 YNGKFRGGPIAKTYYRDADYDGD-VNTYTLQSQTGGNFFTVDTTTG----EISAAKDI-- 2644 Query: 757 ESPRKKYELVI-----RAASPPLWNDVRVEILVT 785 P +Y LVI +PP N+V VT Sbjct: 2645 --PVGEYSLVISVTEVNTGNPPRANEVNFPKTVT 2676 Score = 256 bits (628), Expect = 5e-66 Identities = 252/868 (29%), Positives = 391/868 (45%), Gaps = 86/868 (9%) Query: 11 INVLDCNDHSPVFEMQ---QYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 INV++ ND+ P+F + Q + V + G L A D+DIG + +IE Sbjct: 1590 INVVNINDNEPMFPGETNGQIDRKVAGPFAPGVIATRLTAVDKDIGDRVYYKISIEAENY 1649 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFR--IDGRSGALLTRASLDREKVARYTVLVKATDQASP 125 T++ E + FR I+ R G L + + V V + P Sbjct: 1650 FTID-ERGQLICKNDLKGIASPFRFTIEARDGGLPQKVHTANVLL----VFVNYRPKQQP 1704 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 V + T I P+ E ++SV+ D+ +K + G S Sbjct: 1705 VRVIVPETTRAXTVIT----RVPRILE---SLSVNSDV----------LKVSAQAPGGKS 1747 Query: 186 AIRYAIIGGNTQM--QFSIDSLSGDVSLVKTLDYEQV----RSYRLVIRAQDGGSPSRSN 239 + Y+ + N + +FS+++ +G + LDYEQ+ ++++L +RAQ+ + S Sbjct: 1748 IV-YSPVKANADIDEKFSVET-NGQIKTASQLDYEQLSPGDKTFKLQVRAQEENTNLYS- 1804 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 T + I + DVND+ P F + V EN PIG +++ ++A D D G +TY + Sbjct: 1805 TCSVAITLEDVNDDKPTFDLGNYDARVRENAPIGTTVITIKATDRDTGDAGVVTYFLK-- 1862 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 D ID SG + T DRE Q+ + ++V A D G+ P + + Sbjct: 1863 ---AGSDEHFAIDVNSGTLTTKKSFDREGQSLFSVIVIARDKGNNPGALSEEVAVKVLVV 1919 Query: 360 XXXXX--XFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSIT 415 F +++ ++E GT ++ + ATD D ++ +L Y I+GG+ R F++ Sbjct: 1920 DENDSPPQFDQAEFQTSVSESATIGTSILEVVATDQDIGDNAKLEYFISGGDGRFWFAVQ 1979 Query: 416 --SQNGR--GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN 471 S++GR G + V LDF+ + Y + V+ATD G S T V I ITDAN+ P+F Sbjct: 1980 TISKSGRTYGEVQVDARLDFETKSSYTIDVTATD-GRFSATTRVLITITDANDIVPMFMT 2038 Query: 472 -------AP-YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523 +P YT V E G VL V A D+D N Q T SS A + Sbjct: 2039 LTTPTLLSPIYTGRVSEMTGSGVEVLKVYAVDTD-SPNIQYTLEGSSSYFTIAARQEGGK 2097 Query: 524 FVINPQTGAITT-NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582 FV G I+T ++ LDRE + V A+DG + + +EI+V D+NDN+P F Sbjct: 2098 FV-----GIISTGSQPLDREATPIFSFNVLAKDG---VHTGSAYIEINVTDINDNQPRFP 2149 Query: 583 QQLYTANIMEDALVGTSVSQVGATDAD---VGLNGRIHYELDPKDREEGSFVIDPASGVI 639 LY + E+ GTSV V A D D +G N I Y L D G F ID + ++ Sbjct: 2150 NSLYVGYVEENKAAGTSVMYVQAHDDDDPYLGGNAEIRYTLT--DNAGGKFKIDANTALV 2207 Query: 640 RTNKALDRE-SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698 T + LDRE S + + +A D G S+T + I + D ND PVF +SE Sbjct: 2208 TTEEILDRETSPNSFTITVLATDQGANKLSTTKVATIYVTDANDHAPVFTKRIFRGTVSE 2267 Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758 + G + + A D D GPNA + + + G++ +F ++ +G+ + L+Y + Sbjct: 2268 DVRPGYVVTSVSATDTDTGPNAELEFVVTHGNEPAAFYVDPSKGTVHVSGI----LNY-T 2322 Query: 759 PRKKYELVIRAA--SPPLWND---VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF 813 RK Y L + + P+ +D V I +TD NDNAP+ Q +D P Sbjct: 2323 LRKSYNLTVTVSDRGMPVLSDNSPAYVLITITDANDNAPIFIPNQYNKTVAEDLAVGSPV 2382 Query: 814 GRVPAYDADVTD--KLQYRILSGNNANL 839 V A D D D K + I GN +L Sbjct: 2383 VVVTAVDYDSGDNAKFVFDITGGNPDDL 2410 Score = 221 bits (541), Expect = 2e-55 Identities = 213/815 (26%), Positives = 341/815 (41%), Gaps = 59/815 (7%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F ID +SG + S D E +Y + + A +P + ++S++ + + I D+ D PQ Sbjct: 722 FGIDSKSGRFSSLQSFDYETADKYRIQISAQSGIAP--NIMTSSSDVAITIKDEKDP-PQ 778 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSAIRYAIIGGNTQMQF-SIDSLSG 207 FS+ Y VSV E SV + I+ D D + + + + S+ G Sbjct: 779 FSQSEYKVSVPEGASVRST-LSRGIRFVDEDTLSTQLECSMEEMTSRIPLDYLSVVQDGG 837 Query: 208 DVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265 + V KTLD + ++ D P TT++ + + D N P F + F S Sbjct: 838 ECKFVIEKTLDTFVASKFTFDMKVTDKNFPGMFATTKVEVTVTDTNTYTPVFSRTSFWAS 897 Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY----TGNVDLPITIDPRSGWVYTS 321 + +P S++++ D D G E+TY + D T D +D SG + ++ Sbjct: 898 KPDTLPTDTSVMQLPIIDKDMGSLGEVTYQLIDPTVSAGETSGYDR-FRVDD-SGMIEST 955 Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381 L T Y+L A DGG P AT F Y +AE+ P Sbjct: 956 NILTANTL--YKLQAKAKDGGSPALEATVDVFISVYPSSDTPVRFSQNPYSASIAENSPL 1013 Query: 382 GTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441 T V TAT + + + Y + GG ++ S + G + + + LD ++ + Y L V Sbjct: 1014 NTEVFRATATKSGSSSGIAYSLVGGQIENGNTMFSIDSSGRVLLLRQLDRERTKSYKLYV 1073 Query: 442 SATDSGGRSDTAM---VQINITDANNYAPVFENAPYTASVFED--APIGTTVLVVSATDS 496 T +GG A + +TD N+ P+F D AP T + + A DS Sbjct: 1074 RGTYTGGSLTLATDVECLVTVTDVNDNTPLFTFDRVNKQFVVDNYAPANTIIATLRAVDS 1133 Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKLLDRETMSGYLLTVTARD 555 D G NAQ+T S+ + + A F I+ + + TT KL T+ Y +TV A D Sbjct: 1134 DEGANAQVTMSIQGTVPSNA------PFTIDTPSNVLKTTTKL---STVIDYQITVRATD 1184 Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615 G P T V + V+++ PVF Q YT ++ E+ VG V V AT D N Sbjct: 1185 KGSPPQYSETTVIVKVLNIQ-TPPVFGQAKYTVDVQENTKVGQQVISVKATYGDS--NAL 1241 Query: 616 IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675 + Y + + +F ID +SG I + LDRE + ++ L+ V + G + V+V Sbjct: 1242 LQYSFVSGNLGD-AFCID-SSGQITVAQPLDREVLPSYTLR-VRVALGNNEDFTEVVV-- 1296 Query: 676 KIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735 + DIND P F F+ +E+ GT+IG++ A D D G + + Y D S Sbjct: 1297 SLTDINDDSPTFTKSVYEFFANEDISSGTSIGKVAATDRDSGSHGQISYRFLYASDIQSM 1356 Query: 736 -SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVM 794 + Q + L + LDYE ++ I V I + D+NDN P Sbjct: 1357 DKFDLDQTTGIISLASGKSLDYE------DITI----------AEVRIYLRDINDNDPKF 1400 Query: 795 KDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGNNANLILLNETTGSMTLS 852 D + +V A D D + +++Y I++GN + G + ++ Sbjct: 1401 SAASYHAKLSLDAPVLEHVVQVTATDLDTANNGRIRYSIVAGNQEGAFQVLTDNGLIRVA 1460 Query: 853 PQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRL 886 L T + + D G E K + + V + Sbjct: 1461 KSLTTVAASSFLLTLEAADSGDPERKGSVNVQVNV 1495 Score = 221 bits (539), Expect = 3e-55 Identities = 203/741 (27%), Positives = 343/741 (46%), Gaps = 56/741 (7%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVL---VKATDQASPVSDRLSSTATIHVNI--IDDN 144 F ID SG + + L+ + V+ V ATD+ S LS++ + + + +DDN Sbjct: 408 FAIDSTSGVVTLQTQLEYKGNPAQDVIDLVVTATDRNGQ-SGALSASVNLKIEVLDVDDN 466 Query: 145 DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS 204 +N P F+ + ++V ED +V I ++ ATD+D G++ + Y+II G+ F + + Sbjct: 467 NNAPVFNPQQLELTVSEDSAV--GRTIRRVSATDSDDGSDGQVVYSIIQGSGLGVFQVQA 524 Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 +GD+ + LD E++ Y LVI+A+D + +S+ +++ I+DV+D+ P+F ++ Sbjct: 525 TTGDLIVAAPLDREKMSFYDLVIKAEDKATFPKSSNLYVMVKIQDVDDHFPQFTQPMYYA 584 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 E P + V+ D D G ++Y++T I P SG + T+G + Sbjct: 585 KAPEKSPENTFVTVVKVVDHDLG--ESVSYSITGAS-------SFKIVPTSGLILTTGPI 635 Query: 325 DRETQ-AKYQLLVTATDGG-DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382 D T+ + Y+L+VTAT + AT F Y V + E++ Sbjct: 636 DLTTEPSTYELVVTATSTNYGTTKRATGQVNVEITSKTESPPVFKNTPYAVSVPENQGSI 695 Query: 383 TPVVTLTATDADEDNRLHYEITGGNTRGR-FSITSQNGRGLITVAQPLDFKQERRYVLTV 441 +V + A D + + Y I +RG F I S++GR + Q D++ +Y + + Sbjct: 696 ANLVCVAAIDT-KGQPVIYSI---ESRGEPFGIDSKSGR--FSSLQSFDYETADKYRIQI 749 Query: 442 SATDS---GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV-LVVSATDSD 497 SA + ++ V I I D + P F + Y SV E A + +T+ + D D Sbjct: 750 SAQSGIAPNIMTSSSDVAITIKDEKD-PPQFSQSEYKVSVPEGASVRSTLSRGIRFVDED 808 Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG 557 ++ Q+ S+ S + + V + K LD S + + D Sbjct: 809 T-LSTQLECSMEEMTSRIPLDY--LSVVQDGGECKFVIEKTLDTFVASKFTFDMKVTDKN 865 Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617 P + TT VE++V D N PVF + + A+ + TSV Q+ D D+G G + Sbjct: 866 FPGMFATTKVEVTVTDTNTYTPVFSRTSFWASKPDTLPTDTSVMQLPIIDKDMGSLGEVT 925 Query: 618 YEL-DPK-DREEGS----FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671 Y+L DP E S F +D SG+I + L ++ + L+A A DGG+P +TV Sbjct: 926 YQLIDPTVSAGETSGYDRFRVDD-SGMIESTNILTANTL--YKLQAKAKDGGSPALEATV 982 Query: 672 IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD 731 V I + +D+P F + + I+ENSP+ T + RA G ++ + YS+ GG Sbjct: 983 DVFISVYPSSDTPVRFSQNPYSASIAENSPLNTEV--FRATATKSGSSSGIAYSLVGGQI 1040 Query: 732 SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR----AASPPLWNDVRVEILVTDV 787 N ++ + S + L+ +D K Y+L +R S L DV + VTDV Sbjct: 1041 ENGNTMFSIDSSGRVLLLRQLD---RERTKSYKLYVRGTYTGGSLTLATDVECLVTVTDV 1097 Query: 788 NDNAPVMK----DFQIIFNNY 804 NDN P+ + Q + +NY Sbjct: 1098 NDNTPLFTFDRVNKQFVVDNY 1118 Score = 218 bits (532), Expect = 2e-54 Identities = 193/676 (28%), Positives = 303/676 (44%), Gaps = 40/676 (5%) Query: 134 ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG 193 A + + + D NDN P+FS +Y + D V ++ + ++ ATD D N IRY+I+ Sbjct: 1384 AEVRIYLRDINDNDPKFSAASYHAKLSLDAPVLEH--VVQVTATDLDTANNGRIRYSIVA 1441 Query: 194 GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDN 253 GN + F + + +G + + K+L S+ L + A D G P R + + +N+ + D Sbjct: 1442 GNQEGAFQVLTDNGLIRVAKSLTTVAASSFLLTLEAADSGDPERKGSVNVQVNVF-LPDG 1500 Query: 254 APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313 P+F + +E + + +A ++ L Y + +GN + I+P Sbjct: 1501 PPKFVLDPVIVNATEGIAANQRVAVAKAATSEA-----LKYEIL----SGNTNDMFAINP 1551 Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF---MPGQ 370 SG + T+ +LD E Y + + A D D RSA+ F GQ Sbjct: 1552 SSGVILTTRELDYEEATGYIMNIIARDTRD--RSASVQVIINVVNINDNEPMFPGETNGQ 1609 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 + ++A PG LTA D D +R++Y+I+ F+I RG + L Sbjct: 1610 IDRKVAGPFAPGVIATRLTAVDKDIGDRVYYKISI-EAENYFTIDE---RGQLICKNDLK 1665 Query: 431 FKQERRYVLTVSATDSGGRSDTAMVQINITDAN---NYAPVFENAPYTASVFEDAPIGTT 487 + T+ A D G + + N PV P T Sbjct: 1666 GIASP-FRFTIEARDGGLPQKVHTANVLLVFVNYRPKQQPVRVIVPETTRAXTVITRVPR 1724 Query: 488 VLVVSATDSDV-GINAQITYSLSSEISN-EAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 +L + +SDV ++AQ S S +A A D++F + G I T LD E +S Sbjct: 1725 ILESLSVNSDVLKVSAQAPGGKSIVYSPVKANADIDEKFSVETN-GQIKTASQLDYEQLS 1783 Query: 546 G----YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 + L V A++ +L T V I++ DVND++P F Y A + E+A +GT+V Sbjct: 1784 PGDKTFKLQVRAQEENT-NLYSTCSVAITLEDVNDDKPTFDLGNYDARVRENAPIGTTVI 1842 Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 + ATD D G G + Y L K + F ID SG + T K+ DRE + + +A D Sbjct: 1843 TIKATDRDTGDAGVVTYFL--KAGSDEHFAIDVNSGTLTTKKSFDREGQSLFSVIVIARD 1900 Query: 662 GGTPPQ--SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 G P S V V + + D NDSPP F+ +SE++ IGT+I E+ A D D G N Sbjct: 1901 KGNNPGALSEEVAVKVLVVDENDSPPQFDQAEFQTSVSESATIGTSILEVVATDQDIGDN 1960 Query: 720 AVVHYSIKGGDDSNSFSLET--RQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND 777 A + Y I GGD F+++T + G E+ LD+E+ + Y + + A Sbjct: 1961 AKLEYFISGGDGRFWFAVQTISKSGRTYGEVQVDARLDFET-KSSYTIDVTATDGRFSAT 2019 Query: 778 VRVEILVTDVNDNAPV 793 RV I +TD ND P+ Sbjct: 2020 TRVLITITDANDIVPM 2035 Score = 211 bits (515), Expect = 2e-52 Identities = 225/831 (27%), Positives = 370/831 (44%), Gaps = 87/831 (10%) Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 D+F I+ SG +LT LD E+ Y + + A D DR +S I +N+++ NDN Sbjct: 1545 DMFAINPSSGVILTTRELDYEEATGYIMNIIARD----TRDRSASVQVI-INVVNINDNE 1599 Query: 148 PQFSEKTYTVSVDEDISVTDNP-VIA-KIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205 P F +T +D ++ P VIA ++ A D D+G + +I N F+ID Sbjct: 1600 PMFPGET-NGQIDRKVAGPFAPGVIATRLTAVDKDIGDRVYYKISIEAEN---YFTIDER 1655 Query: 206 SGDVSLVKTLDYEQVRS-YRLVIRAQDGGSPSRSNTTQLLI----------NIRDVNDNA 254 L+ D + + S +R I A+DGG P + +T +L+ +R + Sbjct: 1656 G---QLICKNDLKGIASPFRFTIEARDGGLPQKVHTANVLLVFVNYRPKQQPVRVIVPET 1712 Query: 255 PRFYTSLFQ-ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313 R T + + + E++ + +++V A A G + Y+ + ++D +++ Sbjct: 1713 TRAXTVITRVPRILESLSVNSDVLKVSA-QAPGG--KSIVYSPVKAN--ADIDEKFSVE- 1766 Query: 314 RSGWVYTSGQLDRET----QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 +G + T+ QLD E ++L V A + S T + F G Sbjct: 1767 TNGQIKTASQLDYEQLSPGDKTFKLQVRAQEENTNLYS-TCSVAITLEDVNDDKPTFDLG 1825 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQ 427 Y+ + E+ P GT V+T+ ATD D + + Y + G+ F+I + G +T + Sbjct: 1826 NYDARVRENAPIGTTVITIKATDRDTGDAGVVTYFLKAGSDE-HFAIDVNS--GTLTTKK 1882 Query: 428 PLDFKQERRYVLTVSATDSGGR----SDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 D + + + + V A D G S+ V++ + D N+ P F+ A + SV E A Sbjct: 1883 SFDREGQSLFSVIVIARDKGNNPGALSEEVAVKVLVVDENDSPPQFDQAEFQTSVSESAT 1942 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT-GAITTNKLLDRE 542 IGT++L V ATD D+G NA++ Y +S A Q + +T G + + LD E Sbjct: 1943 IGTSILEVVATDQDIGDNAKLEYFISGGDGRFWFA--VQTISKSGRTYGEVQVDARLDFE 2000 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK--------QQLYTANIMEDA 594 T S Y + VTA DG S TT V I++ D ND P+F +YT + E Sbjct: 2001 TKSSYTIDVTATDG---RFSATTRVLITITDANDIVPMFMTLTTPTLLSPIYTGRVSEMT 2057 Query: 595 LVGTSVSQVGATDAD-----VGLNGRIHYELDPKDREEGSFVIDPASGVIRT-NKALDRE 648 G V +V A D D L G Y +E G FV G+I T ++ LDRE Sbjct: 2058 GSGVEVLKVYAVDTDSPNIQYTLEGSSSYFTIAARQEGGKFV-----GIISTGSQPLDRE 2112 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 + +A DG + + + I + DIND+ P F + Y+ EN GT++ Sbjct: 2113 ATPIFSFNVLAKDG---VHTGSAYIEINVTDINDNQPRFPNSLYVGYVEENKAAGTSVMY 2169 Query: 709 IRAHDPDE---GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765 ++AHD D+ G NA + Y++ + F ++ ++ A + T LD E+ + + Sbjct: 2170 VQAHDDDDPYLGGNAEIRYTLT-DNAGGKFKID----ANTALVTTEEILDRETSPNSFTI 2224 Query: 766 VIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD 822 + A + L I VTD ND+APV +D P V A D D Sbjct: 2225 TVLATDQGANKLSTTKVATIYVTDANDHAPVFTKRIFRGTVSEDVRPGYVVTSVSATDTD 2284 Query: 823 V--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 +L++ + GN ++ + G++ +S LN + K + V+V+D Sbjct: 2285 TGPNAELEFVVTHGNEPAAFYVDPSKGTVHVSGILNYTLRKSYNLTVTVSD 2335 Score = 203 bits (496), Expect = 5e-50 Identities = 198/738 (26%), Positives = 323/738 (43%), Gaps = 61/738 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 QI++ D N++ PVFE +Y +V E T++L ++A D DIG+N + Y + Sbjct: 231 QIDIQDTNNNPPVFEKSEYTVTVGEDTPVMTSILRVRARDADIGRNGGIYYYLR------ 284 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N +D ++ + +D +SG T R++ Q + SD Sbjct: 285 -NTQD--FTIDAITGVIRPIRMLDFQSGQQRTLEVTARDR-GSSPKAANVNVQVTIRSDI 340 Query: 130 LSSTATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDADVGA-NSAI 187 + + D + P F E ++T+S+ ED V N I +KA D D G+ N + Sbjct: 341 SGYPPVVVPSSSSDRNRPPVFPEGSSFTLSIREDFPV--NGAIQVVKANDPDAGSTNGQL 398 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS---YRLVIRAQD--GGSPSRSNTTQ 242 RY++ G N F+IDS SG V+L L+Y+ + LV+ A D G S + S + Sbjct: 399 RYSLSGNN---NFAIDSTSGVVTLQTQLEYKGNPAQDVIDLVVTATDRNGQSGALSASVN 455 Query: 243 LLINIRDV--NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 L I + DV N+NAP F + +VSE+ +G +I RV A D+D+G + ++ Y++ Sbjct: 456 LKIEVLDVDDNNNAPVFNPQQLELTVSEDSAVGRTIRRVSATDSDDGSDGQVVYSIIQGS 515 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 G + T +G + + LDRE + Y L++ A D P+S+ Sbjct: 516 GLGVFQVQAT----TGDLIVAAPLDREKMSFYDLVIKAEDKATFPKSSNLYVMVKIQDVD 571 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420 F Y + E P T V + D D + Y ITG ++ F I + Sbjct: 572 DHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGESVSYSITGASS---FKIVPTS-- 626 Query: 421 GLITVAQPLDFKQE-RRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTA 476 GLI P+D E Y L V+AT + + T V + IT PVF+N PY Sbjct: 627 GLILTTGPIDLTTEPSTYELVVTATSTNYGTTKRATGQVNVEITSKTESPPVFKNTPYAV 686 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 SV E+ ++ V+A D+ + YS+ S + F I+ ++G ++ Sbjct: 687 SVPENQGSIANLVCVAAIDTK---GQPVIYSIES---------RGEPFGIDSKSGRFSSL 734 Query: 537 KLLDRETMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 + D ET Y + ++A+ G P+ ++ ++DV I++ D D P F Q Y ++ E A Sbjct: 735 QSFDYETADKYRIQISAQSGIAPNIMTSSSDVAITIKDEKD-PPQFSQSEYKVSVPEGAS 793 Query: 596 VGTSVSQ-VGATDADVGLNGRIHYELDPKDR----EEGSFVIDPASGVIRTNKALDR--E 648 V +++S+ + D D L+ ++ ++ + S V D K LD Sbjct: 794 VRSTLSRGIRFVDEDT-LSTQLECSMEEMTSRIPLDYLSVVQDGGECKFVIEKTLDTFVA 852 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 S T D+K D P +T V + + D N PVF + P T++ + Sbjct: 853 SKFTFDMKVT--DKNFPGMFATTKVEVTVTDTNTYTPVFSRTSFWASKPDTLPTDTSVMQ 910 Query: 709 IRAHDPDEGPNAVVHYSI 726 + D D G V Y + Sbjct: 911 LPIIDKDMGSLGEVTYQL 928 Score = 201 bits (491), Expect = 2e-49 Identities = 226/886 (25%), Positives = 380/886 (42%), Gaps = 81/886 (9%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 ++ + + D +DH P F Y A E + T V +K D D+G++ V Y+I + Sbjct: 561 LYVMVKIQDVDDHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGES--VSYSITGAS 618 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLD-REKVARYTVLVKATDQASP 125 + F+I SG +LT +D + + Y ++V AT Sbjct: 619 S----------------------FKIVPTSGLILTTGPIDLTTEPSTYELVVTATSTNYG 656 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 + R +T ++V I ++ P F Y VSV E+ N V + A D Sbjct: 657 TTKR--ATGQVNVEITSKTESPPVFKNTPYAVSVPENQGSIANLVC--VAAIDTK---GQ 709 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLL 244 + Y+I F IDS SG S +++ DYE YR+ I AQ G +P+ ++++ + Sbjct: 710 PVIYSIESRGEP--FGIDSKSGRFSSLQSFDYETADKYRIQISAQSGIAPNIMTSSSDVA 767 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 I I+D D P+F S ++ SV E + ++ R + ++ ++ +L +M + Sbjct: 768 ITIKDEKD-PPQFSQSEYKVSVPEGASVRSTLSRGIRFVDEDTLSTQLECSMEEMTSRIP 826 Query: 305 VD-LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 +D L + D LD +K+ + TD P AT Sbjct: 827 LDYLSVVQDGGECKFVIEKTLDTFVASKFTFDMKVTDKNFPGMFATTKVEVTVTDTNTYT 886 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYE-----ITGGNTRG--RFSI 414 F + + P T V+ L D D + + Y+ ++ G T G RF + Sbjct: 887 PVFSRTSFWASKPDTLPTDTSVMQLPIIDKDMGSLGEVTYQLIDPTVSAGETSGYDRFRV 946 Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITD-ANNYAPV-FENA 472 G+I L Y L A D G + A V + I+ ++ PV F Sbjct: 947 DDS---GMIESTNILT--ANTLYKLQAKAKDGGSPALEATVDVFISVYPSSDTPVRFSQN 1001 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 PY+AS+ E++P+ T V +AT S G ++ I YSL + + + + + F I+ +G Sbjct: 1002 PYSASIAENSPLNTEVFRATATKS--GSSSGIAYSL---VGGQ-IENGNTMFSID-SSGR 1054 Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE--ISVVDVNDNEPVFKQQLYTANI 590 + + LDRE Y L V G SL+ TDVE ++V DVNDN P+F Sbjct: 1055 VLLLRQLDRERTKSYKLYVRGTYTG-GSLTLATDVECLVTVTDVNDNTPLFTFDRVNKQF 1113 Query: 591 MED--ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648 + D A T ++ + A D+D G N ++ + F ID S V++T L Sbjct: 1114 VVDNYAPANTIIATLRAVDSDEGANAQVTMSIQGTVPSNAPFTIDTPSNVLKTTTKLS-- 1171 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 +V + + A D G+PPQ S V +K+ +I +PPVF T + EN+ +G + Sbjct: 1172 TVIDYQITVRATDKGSPPQYSETTVIVKVLNIQ-TPPVFGQAKYTVDVQENTKVGQQVIS 1230 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768 ++A D NA++ YS G+ ++F +++ ++ LD E Y L +R Sbjct: 1231 VKATYGDS--NALLQYSFVSGNLGDAFCIDS-----SGQITVAQPLDREV-LPSYTLRVR 1282 Query: 769 AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--K 826 A + V + +TD+ND++P F +D G+V A D D + Sbjct: 1283 VALGNNEDFTEVVVSLTDINDDSPTFTKSVYEFFANEDISSGTSIGKVAATDRDSGSHGQ 1342 Query: 827 LQYRILSGN---NANLILLNETTGSMTLSPQLNTNVPKLATMEVSV 869 + YR L + + + L++TTG ++L+ + + + EV + Sbjct: 1343 ISYRFLYASDIQSMDKFDLDQTTGIISLASGKSLDYEDITIAEVRI 1388 Score = 200 bits (488), Expect = 4e-49 Identities = 232/898 (25%), Positives = 382/898 (42%), Gaps = 93/898 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-LKATDQDIGKNAEVEYTIELVTADT 69 I + D D P F +Y+ SV EGAS +T+ ++ D+D + ++E ++E +T+ Sbjct: 768 ITIKDEKD-PPQFSQSEYKVSVPEGASVRSTLSRGIRFVDEDT-LSTQLECSMEEMTSRI 825 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 P D VQD G + +LD +++T +K TD+ P Sbjct: 826 --PLD-------YLSVVQD-----GGECKFVIEKTLDTFVASKFTFDMKVTDKNFP---G 868 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + +T + V + D N P FS ++ S + + TD V+ ++ D D+G+ + Y Sbjct: 869 MFATTKVEVTVTDTNTYTPVFSRTSFWASKPDTLP-TDTSVM-QLPIIDKDMGSLGEVTY 926 Query: 190 AII-----GGNTQM--QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 +I G T +F +D SG + L + Y+L +A+DGGSP+ T Sbjct: 927 QLIDPTVSAGETSGYDRFRVDD-SGMIESTNILTANTL--YKLQAKAKDGGSPALEATVD 983 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 + I++ +D RF + + S++EN P+ + R A G ++ + Y++ Sbjct: 984 VFISVYPSSDTPVRFSQNPYSASIAENSPLNTEVFRATA--TKSGSSSGIAYSLVGGQIE 1041 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTAT-DGGDPPRSATATXXXXXXXXXX 361 N + +ID SG V QLDRE Y+L V T GG + Sbjct: 1042 -NGNTMFSIDS-SGRVLLLRQLDRERTKSYKLYVRGTYTGGSLTLATDVECLVTVTDVND 1099 Query: 362 XXXXFMPGQYEVELAEDE--PPGTPVVTLTATDADEDNRLHYEIT-GGNTRGRFSITSQN 418 F + + D P T + TL A D+DE ++ G T Sbjct: 1100 NTPLFTFDRVNKQFVVDNYAPANTIIATLRAVDSDEGANAQVTMSIQGTVPSNAPFTIDT 1159 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDAN-NYAPVFENAPYTAS 477 ++ L + Y +TV ATD G + + + N PVF A YT Sbjct: 1160 PSNVLKTTTKLSTVID--YQITVRATDKGSPPQYSETTVIVKVLNIQTPPVFGQAKYTVD 1217 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 V E+ +G V+ V AT D NA + YS S +A F I+ +G IT + Sbjct: 1218 VQENTKVGQQVISVKATYGDS--NALLQYSFVSGNLGDA-------FCID-SSGQITVAQ 1267 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LDRE + Y L V G + D T+V +S+ D+ND+ P F + +Y ED G Sbjct: 1268 PLDREVLPSYTLRVRVALG---NNEDFTEVVVSLTDINDDSPTFTKSVYEFFANEDISSG 1324 Query: 598 TSVSQVGATDADVGLNGRIHYE-LDPKDREE-GSFVIDPASGVIR--TNKALDRESVATH 653 TS+ +V ATD D G +G+I Y L D + F +D +G+I + K+LD E + Sbjct: 1325 TSIGKVAATDRDSGSHGQISYRFLYASDIQSMDKFDLDQTTGIISLASGKSLDYEDITIA 1384 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713 + V I + DIND+ P F + +S ++P+ + ++ A D Sbjct: 1385 E------------------VRIYLRDINDNDPKFSAASYHAKLSLDAPVLEHVVQVTATD 1426 Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK-AELVTMVDLDYESPRKKYELVIRAAS- 771 D N + YSI G+ +F + T G + A+ +T V + L + AA Sbjct: 1427 LDTANNGRIRYSIVAGNQEGAFQVLTDNGLIRVAKSLTTV------AASSFLLTLEAADS 1480 Query: 772 --PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQY 829 P V V++ V + D P +I N + + RV A ++ L+Y Sbjct: 1481 GDPERKGSVNVQVNVF-LPDGPPKFVLDPVIVNATEG---IAANQRVAVAKAATSEALKY 1536 Query: 830 RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887 ILSGN ++ +N ++G + + +L+ M + D + A +Q+ + ++ Sbjct: 1537 EILSGNTNDMFAINPSSGVILTTRELDYEEATGYIMNIIARD-TRDRSASVQVIINVV 1593 Score = 180 bits (438), Expect = 5e-43 Identities = 217/820 (26%), Positives = 352/820 (42%), Gaps = 86/820 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTL-KATDQDIGKNAEVEYTIELVTAD 68 +I V D N+ P F Y + E A+ GTTV L K +D ++ Y E+V+ + Sbjct: 119 RITVTDTNNFQPTFGADFYLGYIAEEAAQGTTVGGLEKCHAEDKDRSGIDRY--EIVSGN 176 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 E Q + + TR D + + T+ V+A D Sbjct: 177 ----ERGYFVAETKTVGAQKFLVLKATN----TRIVRDPARPS-ITLTVRANDGGG---- 223 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 L T I ++I D N+N P F + YTV+V ED V + I +++A DAD+G N I Sbjct: 224 -LHGTTRIQIDIQDTNNNPPVFEKSEYTVTVGEDTPVMTS--ILRVRARDADIGRNGGIY 280 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y + NTQ F+ID+++G + ++ LD++ + L + A+D GS ++ + + IR Sbjct: 281 YYL--RNTQ-DFTIDAITGVIRPIRMLDFQSGQQRTLEVTARDRGSSPKAANVNVQVTIR 337 Query: 249 -DVND-------------NAPRFYT--SLFQESVSENVPIGYSIVRVQAYDADEG-VNAE 291 D++ N P + S F S+ E+ P+ +I V+A D D G N + Sbjct: 338 SDISGYPPVVVPSSSSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKANDPDAGSTNGQ 397 Query: 292 LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD---RETQAKYQLLVTATD----GGDP 344 L Y++ +GN + ID SG V QL+ Q L+VTATD G Sbjct: 398 LRYSL-----SGNNN--FAIDSTSGVVTLQTQLEYKGNPAQDVIDLVVTATDRNGQSGAL 450 Query: 345 PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYE 402 S F P Q E+ ++ED G + ++ATD+D+ D ++ Y Sbjct: 451 SASVNLKIEVLDVDDNNNAPVFNPQQLELTVSEDSAVGRTIRRVSATDSDDGSDGQVVYS 510 Query: 403 ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINIT 460 I G+ G F + + G + VA PLD ++ Y L + A D +S V + I Sbjct: 511 IIQGSGLGVFQVQATTGD--LIVAAPLDREKMSFYDLVIKAEDKATFPKSSNLYVMVKIQ 568 Query: 461 DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520 D +++ P F Y A E +P T V VV D D+G ++YS++ S Sbjct: 569 DVDDHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLG--ESVSYSITGASS------- 619 Query: 521 DQQFVINPQTGAITTNKLLDRET-MSGYLLTVTARDGGVPSLSDTT-DVEISVVDVNDNE 578 F I P +G I T +D T S Y L VTA + T V + + ++ Sbjct: 620 ---FKIVPTSGLILTTGPIDLTTEPSTYELVVTATSTNYGTTKRATGQVNVEITSKTESP 676 Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638 PVFK Y ++ E+ ++ V A D + Y ++ + F ID SG Sbjct: 677 PVFKNTPYAVSVPENQGSIANLVCVAAIDTK---GQPVIYSIESRGE---PFGIDSKSGR 730 Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPP-QSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697 + ++ D E+ + ++ A G P +S+ V I I+D D PP F + Sbjct: 731 FSSLQSFDYETADKYRIQISAQSGIAPNIMTSSSDVAITIKDEKD-PPQFSQSEYKVSVP 789 Query: 698 ENSPIGTTIGE-IRAHDPDEGPNAVVHYSIKGGDDSNSFS-LETRQGSDKAELVTMVDLD 755 E + + +T+ IR D D + + S++ L Q + + V LD Sbjct: 790 EGASVRSTLSRGIRFVDEDT-LSTQLECSMEEMTSRIPLDYLSVVQDGGECKFVIEKTLD 848 Query: 756 -YESPRKKYELVIRAAS-PPLWNDVRVEILVTDVNDNAPV 793 + + + +++ + + P ++ +VE+ VTD N PV Sbjct: 849 TFVASKFTFDMKVTDKNFPGMFATTKVEVTVTDTNTYTPV 888 Score = 179 bits (436), Expect = 9e-43 Identities = 191/677 (28%), Positives = 299/677 (44%), Gaps = 80/677 (11%) Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISV-TDNPVIAKIKATDADVGANSAIRYAIIG 193 T+ + + D N+ P F Y + E+ + T + K A D D + RY I+ Sbjct: 117 TLRITVTDTNNFQPTFGADFYLGYIAEEAAQGTTVGGLEKCHAEDKD--RSGIDRYEIVS 174 Query: 194 GNTQMQFSIDSLSGDVS---LVKTLDYEQVR-----SYRLVIRAQDGGSPSRSNTTQLLI 245 GN + F ++ + ++K + VR S L +RA DGG TT++ I Sbjct: 175 GNERGYFVAETKTVGAQKFLVLKATNTRIVRDPARPSITLTVRANDGGG--LHGTTRIQI 232 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 +I+D N+N P F S + +V E+ P+ SI+RV+A DAD G N + Y Y N Sbjct: 233 DIQDTNNNPPVFEKSEYTVTVGEDTPVMTSILRVRARDADIGRNGGIYY------YLRNT 286 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX----------- 354 TID +G + LD ++ + L VTA D G P++A Sbjct: 287 Q-DFTIDAITGVIRPIRMLDFQSGQQRTLEVTARDRGSSPKAANVNVQVTIRSDISGYPP 345 Query: 355 ----XXXXXXXXXXXFMPG-QYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGG 406 F G + + + ED P + + A D D + +L Y ++G Sbjct: 346 VVVPSSSSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKANDPDAGSTNGQLRYSLSGN 405 Query: 407 NTRGRFSITSQNGRGLITVAQPLDFK---QERRYVLTVSATDSGGRSDTAMVQINI---- 459 N F+I S + G++T+ L++K + L V+ATD G+S +N+ Sbjct: 406 N---NFAIDSTS--GVVTLQTQLEYKGNPAQDVIDLVVTATDRNGQSGALSASVNLKIEV 460 Query: 460 --TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517 D NN APVF +V ED+ +G T+ VSATDSD G + Q+ YS+ I + Sbjct: 461 LDVDDNNNAPVFNPQQLELTVSEDSAVGRTIRRVSATDSDDGSDGQVVYSI---IQGSGL 517 Query: 518 AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577 F + TG + LDRE MS Y L + A D S V + + DV+D+ Sbjct: 518 G----VFQVQATTGDLIVAAPLDREKMSFYDLVIKAEDKATFPKSSNLYVMVKIQDVDDH 573 Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637 P F Q +Y A E + T V+ V D D+G + + Y + SF I P SG Sbjct: 574 FPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGES--VSYSI----TGASSFKIVPTSG 627 Query: 638 VIRTNKALD-RESVATHDL--KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694 +I T +D +T++L A + + GT + +T V+++I +SPPVF++ Sbjct: 628 LILTTGPIDLTTEPSTYELVVTATSTNYGT-TKRATGQVNVEITSKTESPPVFKNTPYAV 686 Query: 695 YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDL 754 + EN + + A D P V YSI+ + F ++++ G ++ Sbjct: 687 SVPENQGSIANLVCVAAIDTKGQP---VIYSIESRGE--PFGIDSKSG----RFSSLQSF 737 Query: 755 DYESPRKKYELVIRAAS 771 DYE+ KY + I A S Sbjct: 738 DYET-ADKYRIQISAQS 753 Score = 158 bits (383), Expect = 2e-36 Identities = 161/612 (26%), Positives = 265/612 (43%), Gaps = 66/612 (10%) Query: 223 YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR----FYTSLFQESVSENVPIGYSIVR 278 Y L + + G L I + D N+ P FY E ++ +G + + Sbjct: 98 YVLTVLRRQRGMTEGGIAWTLRITVTDTNNFQPTFGADFYLGYIAEEAAQGTTVG-GLEK 156 Query: 279 VQAYDAD-EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE-TQAKYQLLV 336 A D D G++ + ++ Y + T+ ++ R+ + L V Sbjct: 157 CHAEDKDRSGIDRYEIVSGNERGYFVAETKTVGAQKFLVLKATNTRIVRDPARPSITLTV 216 Query: 337 TATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD-- 394 A DGG T F +Y V + ED P T ++ + A DAD Sbjct: 217 RANDGGG--LHGTTRIQIDIQDTNNNPPVFEKSEYTVTVGEDTPVMTSILRVRARDADIG 274 Query: 395 EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM 454 + ++Y + NT+ F+I + G+I + LDF+ ++ L V+A D G A Sbjct: 275 RNGGIYYYLR--NTQD-FTIDAIT--GVIRPIRMLDFQSGQQRTLEVTARDRGSSPKAAN 329 Query: 455 VQINIT---DANNYAPVF---------------ENAPYTASVFEDAPIGTTVLVVSATDS 496 V + +T D + Y PV E + +T S+ ED P+ + VV A D Sbjct: 330 VNVQVTIRSDISGYPPVVVPSSSSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKANDP 389 Query: 497 DVG-INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD-----RETMSGYLLT 550 D G N Q+ YSLS + F I+ +G +T L+ + + ++T Sbjct: 390 DAGSTNGQLRYSLSG----------NNNFAIDSTSGVVTLQTQLEYKGNPAQDVIDLVVT 439 Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNE--PVFKQQLYTANIMEDALVGTSVSQVGATDA 608 T R+G +LS + +++I V+DV+DN PVF Q + ED+ VG ++ +V ATD+ Sbjct: 440 ATDRNGQSGALSASVNLKIEVLDVDDNNNAPVFNPQQLELTVSEDSAVGRTIRRVSATDS 499 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 D G +G++ Y + + G F + +G + LDRE ++ +DL A D T P+S Sbjct: 500 DDGSDGQVVYSI-IQGSGLGVFQVQATTGDLIVAAPLDREKMSFYDLVIKAEDKATFPKS 558 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 S + V +KI+D++D P F E SP T + ++ D D G + V YSI G Sbjct: 559 SNLYVMVKIQDVDDHFPQFTQPMYYAKAPEKSPENTFVTVVKVVDHDLGES--VSYSITG 616 Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR----VEILV 784 ++SF + G ++T +D + YELV+ A S R V + + Sbjct: 617 ---ASSFKIVPTSGL----ILTTGPIDLTTEPSTYELVVTATSTNYGTTKRATGQVNVEI 669 Query: 785 TDVNDNAPVMKD 796 T ++ PV K+ Sbjct: 670 TSKTESPPVFKN 681 Score = 154 bits (374), Expect = 3e-35 Identities = 148/515 (28%), Positives = 235/515 (45%), Gaps = 50/515 (9%) Query: 377 EDEPPGTPVVTLTATDADEDNRLHYEI-TGGNTRGRFSITSQNGRGLITVAQPLDFK--Q 433 E+EP G V + + ++E + T + R S++G ++ PL + + Sbjct: 37 ENEPEGFRVFSFPSPPSNEIYSFFRALDTASQSALRLFDISEDG--VVVTKNPLVYTDGE 94 Query: 434 ERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491 E YVLTV G ++I +TD NN+ P F Y + E+A GTTV + Sbjct: 95 ENLYVLTVLRRQRGMTEGGIAWTLRITVTDTNNFQPTFGADFYLGYIAEEAAQGTTVGGL 154 Query: 492 SATDSDVGINAQIT-YSLSSEISNEAVAHHDQQFVINPQTGAI---TTNKLLDRETMSGY 547 ++ + I Y + S NE + + Q + T +++ Sbjct: 155 EKCHAEDKDRSGIDRYEIVS--GNERGYFVAETKTVGAQKFLVLKATNTRIVRDPARPSI 212 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 LTV A DGG L TT ++I + D N+N PVF++ YT + ED V TS+ +V A D Sbjct: 213 TLTVRANDGG--GLHGTTRIQIDIQDTNNNPPVFEKSEYTVTVGEDTPVMTSILRVRARD 270 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 AD+G NG I+Y L R F ID +GVIR + LD +S L+ A D G+ P+ Sbjct: 271 ADIGRNGGIYYYL----RNTQDFTIDAITGVIRPIRMLDFQSGQQRTLEVTARDRGSSPK 326 Query: 668 SSTVIVHIKIE-DIN--------------DSPPVF-ESDCLTFYISENSPIGTTIGEIRA 711 ++ V V + I DI+ + PPVF E T I E+ P+ I ++A Sbjct: 327 AANVNVQVTIRSDISGYPPVVVPSSSSDRNRPPVFPEGSSFTLSIREDFPVNGAIQVVKA 386 Query: 712 HDPDEGP-NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770 +DPD G N + YS+ G +N+F++++ G L T ++ + +LV+ A Sbjct: 387 NDPDAGSTNGQLRYSLSG---NNNFAIDSTSGV--VTLQTQLEYKGNPAQDVIDLVVTAT 441 Query: 771 -----SPPLWNDV--RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD- 822 S L V ++E+L D N+NAPV Q+ +D RV A D+D Sbjct: 442 DRNGQSGALSASVNLKIEVLDVDDNNNAPVFNPQQLELTVSEDSAVGRTIRRVSATDSDD 501 Query: 823 -VTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 ++ Y I+ G+ + + TTG + ++ L+ Sbjct: 502 GSDGQVVYSIIQGSGLGVFQVQATTGDLIVAAPLD 536 >UniRef50_UPI000065D51F Cluster: Homolog of Homo sapiens "Fat-like cadherin FATJ protein; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "Fat-like cadherin FATJ protein - Takifugu rubripes Length = 2263 Score = 355 bits (872), Expect = 1e-95 Identities = 275/857 (32%), Positives = 420/857 (49%), Gaps = 71/857 (8%) Query: 12 NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71 NVLD ND+ PVF + A + E GT L+L +D+D G N +V+ +++ Sbjct: 62 NVLDVNDNPPVFSRGTFSAFLLEDTRVGTCFLSLNVSDKDSGDNGDVKLSVD-------- 113 Query: 72 PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131 ED VF I+ S +L +A LDRE Y V V A+D+ P + +L+ Sbjct: 114 GEDE-----------DQVFFINP-SSSLCLKAELDREMQNFYNVTVTASDRVQPPALQLT 161 Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191 STA ++V + D NDN P+F TV + ED ++ + VI I+ D D G+N+ + Y Sbjct: 162 STARVYVTVGDVNDNAPRFVSAN-TVKITEDAAL--HSVIMTIRTEDDDDGSNALVLY-Y 217 Query: 192 IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251 + + FSIDS SG++ L++ L+ E S L + A D GSP + ++ L + I DVN Sbjct: 218 LNTTAEGTFSIDSSSGEIHLMEMLNRELHDSLILTVTAIDEGSPRMTTSSSLTVLIEDVN 277 Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311 ++ P F T L++ +V E+V G S+++V A D D G+N E+ Y M DK P ++ Sbjct: 278 NHDPEFSTDLYKVAVREDVRGGTSLLQVSALDRDIGMNGEVRY-MLDK------ARPFSV 330 Query: 312 DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371 D G V +LDRE+ A+Y L +TA D G+PPRS TA F P Sbjct: 331 DAVRGVVMVMERLDRESDAEYTLTLTAVDLGEPPRSTTAVINITVMDINDFVPSFNPELL 390 Query: 372 EVELAEDEPPGTPVV-TLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 + + E+E + + ++A D D +++L Y I GN G FSIT G + Sbjct: 391 TLHVMENEEDFSKLTYQVSALDEDFGANSQLQYFILSGN-NGHFSITL---NGTFQILHS 446 Query: 429 LDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD + + +V+T+ A DSG + T +QI + D N+ P F Y V ED+P GT Sbjct: 447 LDREVQAVHVVTIIAIDSGSHPLTGTQTLQIIVGDINDNRPAFTGEAYNTIVSEDSPAGT 506 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 +V+A+D D G+N +++Y L A D F I+ +G + T LLDRET++ Sbjct: 507 VFAMVTASDIDEGVNGELSYRL---------AGLDMPFAIDETSGELFTTDLLDRETVAI 557 Query: 547 YLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 Y L V D + LS + V + + DVND+ P F Y A + + G+ V VGA Sbjct: 558 YRLVVIGSDKHLTWPLSSSVIVTVLIGDVNDHWPQFMNGPYVAYVPTGMVAGSVVCAVGA 617 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD-RESVATHDLKAVAIDGGT 664 D D+ LN +HY L F IDP SG + T L E + L D G Sbjct: 618 VDEDIDLNAELHYSL--YGHGSDLFSIDPRSGNVYTTGVLQWAEDLV---LNVHVEDAGE 672 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 P+S T + I+ ++I + P + + L I EN P+GT + + A P V + Sbjct: 673 TPKSDTSTISIRFQNIAEFPQI-SVEILNGSIPENVPVGTLVAVVSAASTRAEP---VSF 728 Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVE 781 + G+ N F ++ G+ L LDYE +K + L++ A ASPP + + Sbjct: 729 YLASGNLDNKFHVDQVSGA----LTVDNPLDYED-KKGFALLMEARDSASPPFSSFEEIH 783 Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNNANL 839 I ++D+NDN P + +++ P V A DAD + + Y I+ GN N Sbjct: 784 ISISDINDNYPQFTQAEYRCEVFEN-HPPSWICDVLAVDADFDNMSLVLYNIIDGNVNNY 842 Query: 840 ILLNETTGSMTLSPQLN 856 +L+ G ++ + L+ Sbjct: 843 FMLDHENGLLSTTAALD 859 Score = 327 bits (803), Expect = 3e-87 Identities = 302/1109 (27%), Positives = 482/1109 (43%), Gaps = 94/1109 (8%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72 V D ND+SP+F Y A + E V+ L ATD D+G+N+++ Y I D N Sbjct: 991 VTDANDNSPLFSHSVYSAVLSETKDKDVFVVQLVATDADLGQNSQIFYVI-----DPSNE 1045 Query: 73 EDAXXXXXXXXXXVQDVFRIDGRSGALLTRA--SLDREKVARYTVLVKATDQASPVSDRL 130 E F ++ SG + ++ +L Y V A D L Sbjct: 1046 E----------------FWVNSPSGEIFSKKPLTLPNSSFELYQFTVFAFDCGDAP---L 1086 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG-ANSAIRY 189 S T+ V + N + P F + ++V + K A D D+ ++SAI+Y Sbjct: 1087 RSNTTVTVRLEPINFHPPSFLPHRRLIPTPYHMAVGTE--VVKFTAIDQDINNSSSAIKY 1144 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 +IGGN F + SG V L ++++ + L ++A D G P S+ ++ I Sbjct: 1145 ILIGGNASSFFWLQEESGKVILEQSVEGSINSFFTLSLQAVDQGYPPLSSLIEVTFEITG 1204 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 N P F SV E++ +G I R+ A D D G N ++Y T + N D P+ Sbjct: 1205 RNQFPPVFREPDVTFSVPEDLVVGSPIGRIHAEDRDYGTNGAISYGFTHE----NQDSPL 1260 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 ++ SG + +LD ET Y L + A DG +S+ F+ Sbjct: 1261 SVGEHSGILTLIKELDFETDRIYHLQMEAKDGAWFTKSSPLNVTVIVLDVNDNPPVFLSS 1320 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 Y + + E+ GT ++ + A DAD + ++ Y + G +F+I G G IT + Sbjct: 1321 SYTISVPENSEIGTSILDVKADDADSSSNAQMLYSLFSGRM-DKFAIDP--GSGTITTSD 1377 Query: 428 PLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 D++QER + +TV A ++G A V I ITD N + P F+ Y VF +A IG Sbjct: 1378 IFDYEQERVFEVTVRAMNAGAHPLFSVARVVIQITDVNEFTPTFDKNQYHFIVFRNARIG 1437 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 T V V+ATD D G Q+ Y++ + + F I+ +G I T+ +L + S Sbjct: 1438 TRVGRVTATDGDSGPAGQVFYTMFGQSKTKG-------FEIDNISGEIYTSGILREQADS 1490 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 LL V AR+ GV + D + + + N PVF +Y+ANI ED+ G+SV VG Sbjct: 1491 RILLKVLARNLGVVTGVDVDETSVHISVTEFNAPVFTSSIYSANITEDSRAGSSVITVGV 1550 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 D D + R+ + ++ + +FV+DP+SGVI N LDRE ++ ++L A G+P Sbjct: 1551 LDQD---SSRVIFSIE-NGNTDLAFVVDPSSGVISVNSELDRELLSFYNLTLKAAPSGSP 1606 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA--VVH 723 + T V + + D+ND+PP + + EN P GT + ++ A DPD PN + Sbjct: 1607 LDAETANVIVTVVDVNDNPP--QLLYTEVQVRENQPQGTIVAKLTALDPDLPPNQGPFAY 1664 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI--RAASPPLWNDVRVE 781 + + D FSL T G EL T LD E LV+ A P L + + Sbjct: 1665 WLVNPPTD---FSL-TPDG----ELSTTRALDREDTSAYQVLVVVRDAGMPQLSSTAMLY 1716 Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLIL 841 I + D NDN + ++ I + FP G G V D D +D I SG N+ Sbjct: 1717 IRIVDENDNPSLPRNITIEVKYFGASFPGGMIGNVHPEDPDDSDTFSCLIKSG-PLNMFT 1775 Query: 842 LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN-EIKAMMQLSVRLITEEMLLNSITVRL 900 T + SP + + V VTD ++ + + ++ + T + + I + Sbjct: 1776 TANDTCELWSSP---FHGEATFNLTVEVTDRLHLPVNNSVYVNYKGFTNASVNSCIFFYV 1832 Query: 901 NDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQD-DTDVTGNILNVSFSARRPDAE 959 + + E+FLS F+ L ++ ++F ++ +++ +++ + E Sbjct: 1833 SSSSREEFLSYKYLRFVKALDSLFNLQASKTHVFGIKHLGSEILLLAAAKNYNGQYLSRE 1892 Query: 960 VGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKF 1019 V V+ + HR L + V + + C+ PC N C L Sbjct: 1893 VAVSVSAA--------------HRKLLETQSNVTISQISGDSCLMGPCQNGAMCSQNLSV 1938 Query: 1020 GNASGFVNSDSVLFRPIYPVTS-FTCQCPEGFTGVNCETILTKASCEVDGDGSICRS--- 1075 G+ + S V+F + P T F+C CP FTG CE + + G+ C + Sbjct: 1939 GHTFAVLESKLVIF--VSPQTEVFSCSCPAAFTGALCEGDVDECDVNPCGNEGTCVNTVG 1996 Query: 1076 GSQCVARREGGILCQGCSIDAAYTTAVCE 1104 G C GG CS D T +C+ Sbjct: 1997 GFSCEC--HGGFSGSVCSTDGC-TDLICQ 2022 Score = 310 bits (761), Expect = 4e-82 Identities = 251/873 (28%), Positives = 394/873 (45%), Gaps = 66/873 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 QI V D ND+ P F + Y V E + +GT + A+D D G N E+ Y + Sbjct: 476 QIIVGDINDNRPAFTGEAYNTIVSEDSPAGTVFAMVTASDIDEGVNGELSYRL------- 528 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + F ID SG L T LDRE VA Y ++V +D+ ++ Sbjct: 529 --------------AGLDMPFAIDETSGELFTTDLLDRETVAIYRLVVIGSDK--HLTWP 572 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LSS+ + V I D ND++PQF Y V + V+ + A D D+ N+ + Y Sbjct: 573 LSSSVIVTVLIGDVNDHWPQFMNGPYVAYV--PTGMVAGSVVCAVGAVDEDIDLNAELHY 630 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 ++ G + + FSID SG+V L + + L + +D G +S+T+ + I ++ Sbjct: 631 SLYGHGSDL-FSIDPRSGNVYTTGVLQWAE--DLVLNVHVEDAGETPKSDTSTISIRFQN 687 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA-DEGVNAELTYTMTDKDYTGNVDLP 308 + + P+ + S+ ENVP+G + V A E V+ L +GN+D Sbjct: 688 IAE-FPQISVEILNGSIPENVPVGTLVAVVSAASTRAEPVSFYLA--------SGNLDNK 738 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 +D SG + LD E + + LL+ A D PP S+ F Sbjct: 739 FHVDQVSGALTVDNPLDYEDKKGFALLMEARDSASPPFSSFEEIHISISDINDNYPQFTQ 798 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVA 426 +Y E+ E+ PP + + A DAD DN + Y I GN F + +N GL++ Sbjct: 799 AEYRCEVFENHPPSW-ICDVLAVDADFDNMSLVLYNIIDGNVNNYFMLDHEN--GLLSTT 855 Query: 427 QPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 LD + + LT+ A + S D A V +++ D N+ AP F ++ V ED+P+ Sbjct: 856 AALDREDISTFNLTIEAAELNNPSHRDRATVIVSVLDRNDNAPRFSQI-FSIEVPEDSPV 914 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 G + + +S+ D D+G NA I Y + ++SN F IN TG IT + LDRET Sbjct: 915 GHSAIQISSFDDDLGTNAVINYFIIDQLSN-------VPFTINFITGFITVKRPLDRETR 967 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 Y+L V+A D + S + DV + V D NDN P+F +Y+A + E V Q+ Sbjct: 968 DQYILKVSANDS---AWSVSMDVTVVVTDANDNSPLFSHSVYSAVLSETKDKDVFVVQLV 1024 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK--ALDRESVATHDLKAVAIDG 662 ATDAD+G N +I Y +DP + E F ++ SG I + K L S + A D Sbjct: 1025 ATDADLGQNSQIFYVIDPSNEE---FWVNSPSGEIFSKKPLTLPNSSFELYQFTVFAFDC 1081 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAV 721 G P S V +++E IN PP F + +GT + + A D D ++ Sbjct: 1082 GDAPLRSNTTVTVRLEPINFHPPSFLPHRRLIPTPYHMAVGTEVVKFTAIDQDINNSSSA 1141 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781 + Y + GG+ S+ F L+ G K L V+ S + PPL + + V Sbjct: 1142 IKYILIGGNASSFFWLQEESG--KVILEQSVEGSINSFFTLSLQAVDQGYPPLSSLIEVT 1199 Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANL 839 +T N PV ++ + F+ +D P GR+ A D D + Y N + Sbjct: 1200 FEITGRNQFPPVFREPDVTFSVPEDLVVGSPIGRIHAEDRDYGTNGAISYGFTHENQDSP 1259 Query: 840 ILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 + + E +G +TL +L+ ++ +++ DG Sbjct: 1260 LSVGEHSGILTLIKELDFETDRIYHLQMEAKDG 1292 Score = 301 bits (738), Expect = 2e-79 Identities = 234/789 (29%), Positives = 374/789 (47%), Gaps = 42/789 (5%) Query: 43 LTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR 102 ++++ + I +N V + +V+A + E + + F +D SGAL Sbjct: 694 ISVEILNGSIPENVPVGTLVAVVSAASTRAEPVSFYLASGN--LDNKFHVDQVSGALTVD 751 Query: 103 ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162 LD E + +L++A D ASP SS IH++I D NDNYPQF++ Y V E+ Sbjct: 752 NPLDYEDKKGFALLMEARDSASPP---FSSFEEIHISISDINDNYPQFTQAEYRCEVFEN 808 Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222 + I + A DAD S + Y II GN F +D +G +S LD E + + Sbjct: 809 HPPS---WICDVLAVDADFDNMSLVLYNIIDGNVNNYFMLDHENGLLSTTAALDREDIST 865 Query: 223 YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY 282 + L I A + +PS + +++++ D NDNAPRF + +F V E+ P+G+S +++ ++ Sbjct: 866 FNLTIEAAELNNPSHRDRATVIVSVLDRNDNAPRF-SQIFSIEVPEDSPVGHSAIQISSF 924 Query: 283 DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG 342 D D G NA + Y + D+ NV P TI+ +G++ LDRET+ +Y L V+A D Sbjct: 925 DDDLGTNAVINYFIIDQ--LSNV--PFTINFITGFITVKRPLDRETRDQYILKVSANDSA 980 Query: 343 DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLH 400 S + F Y L+E + VV L ATDAD +++++ Sbjct: 981 ---WSVSMDVTVVVTDANDNSPLFSHSVYSAVLSETKDKDVFVVQLVATDADLGQNSQIF 1037 Query: 401 YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQI 457 Y I N F + S +G L Y TV A D G RS+T V + Sbjct: 1038 YVIDPSNE--EFWVNSPSGEIFSKKPLTLPNSSFELYQFTVFAFDCGDAPLRSNTT-VTV 1094 Query: 458 NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV-GINAQITYSLSSEISNEA 516 + N + P F +GT V+ +A D D+ ++ I Y L I A Sbjct: 1095 RLEPINFHPPSFLPHRRLIPTPYHMAVGTEVVKFTAIDQDINNSSSAIKYIL---IGGNA 1151 Query: 517 VAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVND 576 + F + ++G + + ++ S + L++ A D G P LS +V + N Sbjct: 1152 SSF----FWLQEESGKVILEQSVEGSINSFFTLSLQAVDQGYPPLSSLIEVTFEITGRNQ 1207 Query: 577 NEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS 636 PVF++ T ++ ED +VG+ + ++ A D D G NG I Y + ++ + S Sbjct: 1208 FPPVFREPDVTFSVPEDLVVGSPIGRIHAEDRDYGTNGAISYGF-THENQDSPLSVGEHS 1266 Query: 637 GVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696 G++ K LD E+ + L+ A DG +SS + V + + D+ND+PPVF S T + Sbjct: 1267 GILTLIKELDFETDRIYHLQMEAKDGAWFTKSSPLNVTVIVLDVNDNPPVFLSSSYTISV 1326 Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756 ENS IGT+I +++A D D NA + YS+ G + F+++ G+ + T DY Sbjct: 1327 PENSEIGTSILDVKADDADSSSNAQMLYSLFSG-RMDKFAIDPGSGT----ITTSDIFDY 1381 Query: 757 ESPRKKYELVIR---AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF 813 E R +E+ +R A + PL++ RV I +TDVN+ P Q F +++ Sbjct: 1382 EQER-VFEVTVRAMNAGAHPLFSVARVVIQITDVNEFTPTFDKNQYHFIVFRNARIGTRV 1440 Query: 814 GRVPAYDAD 822 GRV A D D Sbjct: 1441 GRVTATDGD 1449 Score = 293 bits (720), Expect = 3e-77 Identities = 235/864 (27%), Positives = 398/864 (46%), Gaps = 58/864 (6%) Query: 2 SVPFCIHQQINVL--DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVE 59 S PF ++I++ D ND+ P F +Y V E + + + A D D + V Sbjct: 773 SPPFSSFEEIHISISDINDNYPQFTQAEYRCEVFENHPP-SWICDVLAVDADFDNMSLVL 831 Query: 60 YTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKA 119 Y I V + F +D +G L T A+LDRE ++ + + ++A Sbjct: 832 YNI-------------------IDGNVNNYFMLDHENGLLSTTAALDREDISTFNLTIEA 872 Query: 120 TDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA 179 + +P S R AT+ V+++D NDN P+FS+ +++ V ED V + + +I + D Sbjct: 873 AELNNP-SHR--DRATVIVSVLDRNDNAPRFSQ-IFSIEVPEDSPVGHSAI--QISSFDD 926 Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239 D+G N+ I Y II + + F+I+ ++G +++ + LD E Y L + A D + S Sbjct: 927 DLGTNAVINYFIIDQLSNVPFTINFITGFITVKRPLDRETRDQYILKVSANDS---AWSV 983 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 + + + + D NDN+P F S++ +SE +V++ A DAD G N+++ Y + Sbjct: 984 SMDVTVVVTDANDNSPLFSHSVYSAVLSETKDKDVFVVQLVATDADLGQNSQIFYVIDPS 1043 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQA--KYQLLVTATDGGDPPRSATATXXXXXX 357 + V+ P SG +++ L + YQ V A D GD P + T Sbjct: 1044 NEEFWVNSP------SGEIFSKKPLTLPNSSFELYQFTVFAFDCGDAPLRSNTTVTVRLE 1097 Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR---LHYEITGGNTRGRFSI 414 F+P + + GT VV TA D D +N + Y + GGN F + Sbjct: 1098 PINFHPPSFLPHRRLIPTPYHMAVGTEVVKFTAIDQDINNSSSAIKYILIGGNASSFFWL 1157 Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYAPVFENA 472 ++G+ + + Q ++ + L++ A D G ++++++ IT N + PVF Sbjct: 1158 QEESGK--VILEQSVEGSINSFFTLSLQAVDQGYPPLSSLIEVTFEITGRNQFPPVFREP 1215 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 T SV ED +G+ + + A D D G N I+Y + E + D + +G Sbjct: 1216 DVTFSVPEDLVVGSPIGRIHAEDRDYGTNGAISYGFTHE-------NQDSPLSVGEHSGI 1268 Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592 +T K LD ET Y L + A+DG + S +V + V+DVNDN PVF YT ++ E Sbjct: 1269 LTLIKELDFETDRIYHLQMEAKDGAWFTKSSPLNVTVIVLDVNDNPPVFLSSSYTISVPE 1328 Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652 ++ +GTS+ V A DAD N ++ Y L ++ F IDP SG I T+ D E Sbjct: 1329 NSEIGTSILDVKADDADSSSNAQMLYSLFSGRMDK--FAIDPGSGTITTSDIFDYEQERV 1386 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 ++ A++ G P S V I+I D+N+ P F+ + F + N+ IGT +G + A Sbjct: 1387 FEVTVRAMNAGAHPLFSVARVVIQITDVNEFTPTFDKNQYHFIVFRNARIGTRVGRVTAT 1446 Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP 772 D D GP V Y++ G + F ++ G + D K + + Sbjct: 1447 DGDSGPAGQVFYTMFGQSKTKGFEIDNISGEIYTSGILREQADSRILLKVLARNLGVVTG 1506 Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRIL 832 ++ V I VT+ NAPV N +D V D D + ++ + I Sbjct: 1507 VDVDETSVHISVTEF--NAPVFTSSIYSANITEDSRAGSSVITVGVLDQD-SSRVIFSIE 1563 Query: 833 SGNNANLILLNETTGSMTLSPQLN 856 +GN +++ ++G ++++ +L+ Sbjct: 1564 NGNTDLAFVVDPSSGVISVNSELD 1587 Score = 267 bits (654), Expect = 3e-69 Identities = 217/778 (27%), Positives = 359/778 (46%), Gaps = 45/778 (5%) Query: 87 QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146 + +F + SG L SLD E + Y + V S VS + +++ N++D NDN Sbjct: 15 ESLFLLSPLSGEFLLSRSLDFEVQSLYILTVMVQQGDSQVS-----SVSVYFNVLDVNDN 69 Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206 P FS T++ + ED V + +D D G N ++ ++ G + F I+ S Sbjct: 70 PPVFSRGTFSAFLLEDTRV--GTCFLSLNVSDKDSGDNGDVKLSVDGEDEDQVFFINP-S 126 Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSP---SRSNTTQLLINIRDVNDNAPRFYTSLFQ 263 + L LD E Y + + A D P ++T ++ + + DVNDNAPRF S Sbjct: 127 SSLCLKAELDREMQNFYNVTVTASDRVQPPALQLTSTARVYVTVGDVNDNAPRF-VSANT 185 Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323 ++E+ + I+ ++ D D+G NA + Y + + +ID SG ++ Sbjct: 186 VKITEDAALHSVIMTIRTEDDDDGSNALVLYYLNT-----TAEGTFSIDSSSGEIHLMEM 240 Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383 L+RE L VTA D G P + +++ F Y+V + ED GT Sbjct: 241 LNRELHDSLILTVTAIDEGSPRMTTSSSLTVLIEDVNNHDPEFSTDLYKVAVREDVRGGT 300 Query: 384 PVVTLTATDADEDNRLHYEITGGNTRGR-FSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 ++ ++A D D ++ E+ + R FS+ + RG++ V + LD + + Y LT++ Sbjct: 301 SLLQVSA--LDRDIGMNGEVRYMLDKARPFSVDAV--RGVVMVMERLDRESDAEYTLTLT 356 Query: 443 ATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFE-DAPIGTTVLVVSATDSDVG 499 A D G RS TA++ I + D N++ P F T V E + VSA D D G Sbjct: 357 AVDLGEPPRSTTAVINITVMDINDFVPSFNPELLTLHVMENEEDFSKLTYQVSALDEDFG 416 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 N+Q+ Y + ++ ++ F I G LDRE + +++T+ A D G Sbjct: 417 ANSQLQYFI--------LSGNNGHFSIT-LNGTFQILHSLDREVQAVHVVTIIAIDSGSH 467 Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619 L+ T ++I V D+NDN P F + Y + ED+ GT + V A+D D G+NG + Y Sbjct: 468 PLTGTQTLQIIVGDINDNRPAFTGEAYNTIVSEDSPAGTVFAMVTASDIDEGVNGELSYR 527 Query: 620 LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG-TPPQSSTVIVHIKIE 678 L D F ID SG + T LDRE+VA + L + D T P SS+VIV + I Sbjct: 528 LAGLDM---PFAIDETSGELFTTDLLDRETVAIYRLVVIGSDKHLTWPLSSSVIVTVLIG 584 Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738 D+ND P F + Y+ G+ + + A D D NA +HYS+ G S+ FS++ Sbjct: 585 DVNDHWPQFMNGPYVAYVPTGMVAGSVVCAVGAVDEDIDLNAELHYSLY-GHGSDLFSID 643 Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQ 798 R G+ + T L + V A P + + I ++ + + + Sbjct: 644 PRSGN----VYTTGVLQWAEDLVLNVHVEDAGETPKSDTSTISIRFQNIAEFPQI--SVE 697 Query: 799 IIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 I+ + + PVG V + + + + + + SGN N +++ +G++T+ L+ Sbjct: 698 ILNGSIPENVPVGTLVAVVSAASTRAEPVSFYLASGNLDNKFHVDQVSGALTVDNPLD 755 Score = 250 bits (611), Expect = 6e-64 Identities = 189/617 (30%), Positives = 297/617 (48%), Gaps = 41/617 (6%) Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 I Y+++ + + F + LSG+ L ++LD+E Y L + Q G S + ++ + N Sbjct: 5 ITYSVLEDDGESLFLLSPLSGEFLLSRSLDFEVQSLYILTVMVQQGDS--QVSSVSVYFN 62 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + DVNDN P F F + E+ +G + + D D G N ++ ++ +D D Sbjct: 63 VLDVNDNPPVFSRGTFSAFLLEDTRVGTCFLSLNVSDKDSGDNGDVKLSVDGED----ED 118 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR---SATATXXXXXXXXXXXX 363 I+P S + +LDRE Q Y + VTA+D PP ++TA Sbjct: 119 QVFFINPSSS-LCLKAELDREMQNFYNVTVTASDRVQPPALQLTSTARVYVTVGDVNDNA 177 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTL-TATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422 F+ V++ ED + ++T+ T D D N L G FSI S +G Sbjct: 178 PRFVSAN-TVKITEDAALHSVIMTIRTEDDDDGSNALVLYYLNTTAEGTFSIDSSSGE-- 234 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480 I + + L+ + +LTV+A D G + ++ + + I D NN+ P F Y +V E Sbjct: 235 IHLMEMLNRELHDSLILTVTAIDEGSPRMTTSSSLTVLIEDVNNHDPEFSTDLYKVAVRE 294 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 D GT++L VSA D D+G+N ++ Y L + F ++ G + + LD Sbjct: 295 DVRGGTSLLQVSALDRDIGMNGEVRYMLDKA----------RPFSVDAVRGVVMVMERLD 344 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 RE+ + Y LT+TA D G P S T + I+V+D+ND P F +L T ++ME+ + + Sbjct: 345 RESDAEYTLTLTAVDLGEPPRSTTAVINITVMDINDFVPSFNPELLTLHVMENEEDFSKL 404 Query: 601 S-QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 + QV A D D G N ++ Y + G F I +G + +LDRE A H + +A Sbjct: 405 TYQVSALDEDFGANSQLQYFI--LSGNNGHFSI-TLNGTFQILHSLDREVQAVHVVTIIA 461 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 ID G+ P + T + I + DIND+ P F + +SE+SP GT + A D DEG N Sbjct: 462 IDSGSHPLTGTQTLQIIVGDINDNRPAFTGEAYNTIVSEDSPAGTVFAMVTASDIDEGVN 521 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP----PLW 775 + Y + G D F+++ G EL T LD E+ Y LV+ + PL Sbjct: 522 GELSYRLAGLD--MPFAIDETSG----ELFTTDLLDRETV-AIYRLVVIGSDKHLTWPLS 574 Query: 776 NDVRVEILVTDVNDNAP 792 + V V +L+ DVND+ P Sbjct: 575 SSVIVTVLIGDVNDHWP 591 Score = 208 bits (507), Expect = 2e-51 Identities = 168/572 (29%), Positives = 271/572 (47%), Gaps = 36/572 (6%) Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 + P SG S LD E Q+ Y L V G S + F G Sbjct: 20 LSPLSGEFLLSRSLDFEVQSLYILTVMVQQGDSQVSSVSV--YFNVLDVNDNPPVFSRGT 77 Query: 371 YEVELAEDEPPGTPVVTLTATDADE-DNR-LHYEITGGNTRGRFSITSQNGRGLITVAQP 428 + L ED GT ++L +D D DN + + G + F I N + + Sbjct: 78 FSAFLLEDTRVGTCFLSLNVSDKDSGDNGDVKLSVDGEDEDQVFFI---NPSSSLCLKAE 134 Query: 429 LDFKQERRYVLTVSATD-----SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 LD + + Y +TV+A+D + + TA V + + D N+ AP F +A T + EDA Sbjct: 135 LDREMQNFYNVTVTASDRVQPPALQLTSTARVYVTVGDVNDNAPRFVSAN-TVKITEDAA 193 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 + + ++ + D D G NA + Y L++ F I+ +G I ++L+RE Sbjct: 194 LHSVIMTIRTEDDDDGSNALVLYYLNTTAEGT--------FSIDSSSGEIHLMEMLNREL 245 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 +LTVTA D G P ++ ++ + + + DVN+++P F LY + ED GTS+ QV Sbjct: 246 HDSLILTVTAIDEGSPRMTTSSSLTVLIEDVNNHDPEFSTDLYKVAVREDVRGGTSLLQV 305 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 A D D+G+NG + Y LD K R F +D GV+ + LDRES A + L A+D G Sbjct: 306 SALDRDIGMNGEVRYMLD-KAR---PFSVDAVRGVVMVMERLDRESDAEYTLTLTAVDLG 361 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN-SPIGTTIGEIRAHDPDEGPNAVV 722 PP+S+T +++I + DIND P F + LT ++ EN ++ A D D G N+ + Sbjct: 362 EPPRSTTAVINITVMDINDFVPSFNPELLTLHVMENEEDFSKLTYQVSALDEDFGANSQL 421 Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEI 782 Y I G++ + FS+ T G+ +++ +D + ++ + I + S PL ++I Sbjct: 422 QYFILSGNNGH-FSI-TLNGT--FQILHSLDREVQAVHVVTIIAIDSGSHPLTGTQTLQI 477 Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDAD--VTDKLQYRILSGNNANL 839 +V D+NDN P + + P G F V A D D V +L YR L+G + Sbjct: 478 IVGDINDNRPAFTG-EAYNTIVSEDSPAGTVFAMVTASDIDEGVNGELSYR-LAGLDMP- 534 Query: 840 ILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 ++ET+G + + L+ + + V +D Sbjct: 535 FAIDETSGELFTTDLLDRETVAIYRLVVIGSD 566 Score = 67.7 bits (158), Expect = 4e-09 Identities = 52/172 (30%), Positives = 74/172 (43%), Gaps = 20/172 (11%) Query: 1044 CQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVC 1103 CQC GF G CE + C S C GS C+ + G C + C Sbjct: 2036 CQCVSGFEGEMCERFIDH--CR----SSPCIQGS-CINSQTGF----SCDCPFGVSGVHC 2084 Query: 1104 ELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSE 1163 + + F SF+ FP L RR + + L+FAT + LLLYN +FLALE++ Sbjct: 2085 DELSYGFQEMSFIEFPPLDRRINL-VSLEFATLQKNSLLLYNPGGPSSREFLALEILDG- 2142 Query: 1164 AGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDC 1215 + S+ LG G + V DG +HTV I ++ +D+C Sbjct: 2143 -------AVHLSYDLGSGPERLQTNIQVSDGDFHTVTIRRIGYMGSLRVDNC 2187 Score = 37.9 bits (84), Expect = 4.0 Identities = 21/65 (32%), Positives = 25/65 (38%), Gaps = 5/65 (7%) Query: 1517 CMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPCGAARCVPDQTPKGYSC 1573 C IC CV C C +G G C + C PC C+ QT G+SC Sbjct: 2016 CTDLICQNGGTCVVRPGGQHCQCVSGFEGEMCERFIDHCRSSPCIQGSCINSQT--GFSC 2073 Query: 1574 ACEPG 1578 C G Sbjct: 2074 DCPFG 2078 >UniRef50_Q9H251 Cluster: Cadherin-23 precursor; n=51; Euteleostomi|Rep: Cadherin-23 precursor - Homo sapiens (Human) Length = 3354 Score = 355 bits (872), Expect = 1e-95 Identities = 274/879 (31%), Positives = 424/879 (48%), Gaps = 59/879 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +N+LD ND+ P F+ + A V EG +G ++ + A D D G N V Y + V + Sbjct: 878 VNLLDLNDNDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRMP-VGMPRM 936 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F I+ SG ++T LDRE++A Y + V A+D +P Sbjct: 937 D------------------FLINSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTK--- 975 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SST+T+ ++++D ND P F Y VSV ED+ + + TD DVG N+ + Y Sbjct: 976 SSTSTLTIHVLDVNDETPTFFPAVYNVSVSEDVPREFR--VVWLNCTDNDVGLNAELSYF 1033 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR--SNTTQLLINIR 248 I GGN +FS+ V V LD E +Y L++ A D G + + T + + + Sbjct: 1034 ITGGNVDGKFSVGYRDAVVRTVVGLDRETTAAYMLILEAIDNGPVGKRHTGTATVFVTVL 1093 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 DVNDN P F S ++ SV E++P G+SI++++A DADEG + Y + ++ N + Sbjct: 1094 DVNDNRPIFLQSSYEASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIH 1153 Query: 309 ITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 ++ +G + + LDRE + + L+V A + P ++ F Sbjct: 1154 VS----NGLLMRGPRPLDRERNSSHVLIVEAYNHDLGPMRSSVRVIVYVEDINDEAPVFT 1209 Query: 368 PGQY-EVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLIT 424 QY + L E GT V+ + ATD D + ++Y I G G+F I GLI Sbjct: 1210 QQQYSRLGLRETAGIGTSVIVVQATDRDSGDGGLVNYRILSG-AEGKFEI--DESTGLII 1266 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDAN--NYAPVFENAPYTASVFEDA 482 LD++ + Y++ VSATD + + IT N + A F NA Y A++ E+ Sbjct: 1267 TVNYLDYETKTSYMMNVSATDQAPPFNQGFCSVYITLLNELDEAVQFSNASYEAAILENL 1326 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 +GT ++ V A D +N QITY + S +A A F I+ TG IT L+DRE Sbjct: 1327 ALGTEIVRVQAYSID-NLN-QITYRFDAYTSTQAKA----LFKIDAITGVITVQGLVDRE 1380 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA-NIMEDALVGTSVS 601 Y LTV A DGG P + T V I+V+D NDN P F +A +I ED VG V+ Sbjct: 1381 KGDFYTLTVVADDGG-PKVDSTVKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVGQRVA 1439 Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVI---DPASGVIRTNKALDRESVATHDLKAV 658 V A D D G NG++ + L G+F I + + G + + LDRE + + L+ V Sbjct: 1440 TVKAWDPDAGSNGQVVFSL-ASGNIAGAFEIVTTNDSIGEVFVARPLDREELDHYILQVV 1498 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC-LTFYISENSPIGTTIGEIRAHDPDEG 717 A D GTPP+ I+ + I DIND+PPV ES ++EN GT + ++RA D D G Sbjct: 1499 ASDRGTPPRKKDHILQVTILDINDNPPVIESPFGYNVSVNENVGGGTAVVQVRATDRDIG 1558 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND 777 N+V+ Y I G+ +F ++ R + A D + +S V +P L Sbjct: 1559 INSVLSYYITEGNKDMTFRMD-RISGEIATRPAPPDRERQSFYHLVATVEDEGTPTLSAT 1617 Query: 778 VRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILS 833 V + + D NDNAP+ + ++++ + D + A D D + Y I++ Sbjct: 1618 THVYVTIVDENDNAPMFQQPHYEVLLDEGPDTLNTSLI-TIQALDLDEGPNGTVTYAIVA 1676 Query: 834 GNNANLILLNETTGSMTLSPQLNTNVPK-LATMEVSVTD 871 GN N ++ G +T + +L+ + T+ V+ TD Sbjct: 1677 GNIVNTFRIDRHMGVITAAKELDYEISHGRYTLIVTATD 1715 Score = 350 bits (861), Expect = 3e-94 Identities = 274/832 (32%), Positives = 400/832 (48%), Gaps = 85/832 (10%) Query: 10 QINVLDCNDHSPVFEMQ-QYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68 Q+ +LD ND+ PV E Y SV E GT V+ ++ATD+DIG N+ + Y I D Sbjct: 1514 QVTILDINDNPPVIESPFGYNVSVNENVGGGTAVVQVRATDRDIGINSVLSYYITEGNKD 1573 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR-ASLDREKVARYTVLVKATDQASPVS 127 FR+D SG + TR A DRE+ + Y ++ D+ +P Sbjct: 1574 M-------------------TFRMDRISGEIATRPAPPDRERQSFYHLVATVEDEGTPT- 1613 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 LS+T ++V I+D+NDN P F + Y V +DE + +I I+A D D G N + Sbjct: 1614 --LSATTHVYVTIVDENDNAPMFQQPHYEVLLDEGPDTLNTSLIT-IQALDLDEGPNGTV 1670 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGG---SPSRSNTTQL 243 YAI+ GN F ID G ++ K LDYE Y L++ A D S ++TT + Sbjct: 1671 TYAIVAGNIVNTFRIDRHMGVITAAKELDYEISHGRYTLIVTATDQCPILSHRLTSTTTV 1730 Query: 244 LINIRDVNDNAPRF---YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 L+N+ D+NDN P F Y F+ V+E P G + A+D D G N ++ Y++ D D Sbjct: 1731 LVNVNDINDNVPTFPRDYEGPFE--VTEGQP-GPRVWTFLAHDRDSGPNGQVEYSIMDGD 1787 Query: 301 YTGNVDLPITIDPRSGW--VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358 G I P G V +LDRET A Y L + A D G PP S+T Sbjct: 1788 PLGE----FVISPVEGVLRVRKDVELDRETIAFYNLTICARDRGMPPLSSTMLVGIRVLD 1843 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITS 416 + + ++E+ P + V + A+DAD + RL + IT GN F I + Sbjct: 1844 INDNDPVLLNLPMNITISENSPVSSFVAHVLASDADSGCNARLTFNITAGNRERAFFINA 1903 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSG-----GRSDTAMVQINITDANNYAPVFEN 471 G ++TV +PLD ++ Y LT+S D+ R D ++ I ++D N+ P+F Sbjct: 1904 TTG--IVTVNRPLDRERIPEYKLTISVKDNPENPRIARRDYDLLLIFLSDENDNHPLFTK 1961 Query: 472 APYTASVFEDAPIGTTVLVVS----ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527 + Y A V E++P GT + V++ A D+D I A +TY L S F IN Sbjct: 1962 STYQAEVMENSPAGTPLTVLNGPILALDADQDIYAVVTYQLLGAQSG--------LFDIN 2013 Query: 528 PQTGAITTNK--LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585 TG +T ++DRE S +L + + L+ T + I+++D NDN P F Sbjct: 2014 SSTGVVTVRSGVIIDREAFSPPILELLLLAEDIGLLNSTAHLLITILDDNDNRPTFSPAT 2073 Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT-NKA 644 T +++E+ G SV QV ATD D GLNG + Y ++ ++ F+I +GVIR N Sbjct: 2074 LTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQDR--FLIHLVTGVIRVGNAT 2131 Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 +DRE ++ L VA D GT P S T IV I I+DINDS P F + T + E++ GT Sbjct: 2132 IDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVSVLESAEPGT 2191 Query: 705 TIGEIRAHDPDEGPNAVVH-YSIKGGDDS--------NSFSLETRQGS------DKAELV 749 I I A D D P H I DD+ ++F++ GS ELV Sbjct: 2192 VIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNINTGSVMVKSPMNRELV 2251 Query: 750 TMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801 ++ +L R+ S P + ++ + V DVNDN P K F I + Sbjct: 2252 ATYEVTLSVIDNASDLPERSVSVP---NAKLTVNVLDVNDNTPQFKPFGITY 2300 Score = 349 bits (857), Expect = 9e-94 Identities = 268/859 (31%), Positives = 406/859 (47%), Gaps = 51/859 (5%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I +LD ND+ P ++ Y ++ E + V T+ A D D+G+N + Y+I+ Sbjct: 766 ITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQ------- 818 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P + ++ + R A L R+ ++V TD P + Sbjct: 819 -PPNKFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRK------IVVSVTDCGRPPL-KA 870 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +S+AT+ VN++D NDN P F + V E I + I ++ A D D G N + Y Sbjct: 871 TSSATVFVNLLDLNDNDPTFQNLPFVAEVLEGIPAGVS--IYQVVAIDLDEGLNGLVSYR 928 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + G +M F I+S SG V LD E++ Y+L + A D G+P++S+T+ L I++ DV Sbjct: 929 MPVGMPRMDFLINSSSGVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDV 988 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 ND P F+ +++ SVSE+VP + +V + D D G+NAEL+Y +T GNVD + Sbjct: 989 NDETPTFFPAVYNVSVSEDVPREFRVVWLNCTDNDVGLNAELSYFITG----GNVDGKFS 1044 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR--SATATXXXXXXXXXXXXXXFMP 368 + R V T LDRET A Y L++ A D G + + TAT F+ Sbjct: 1045 VGYRDAVVRTVVGLDRETTAAYMLILEAIDNGPVGKRHTGTATVFVTVLDVNDNRPIFLQ 1104 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVA 426 YE + ED P G ++ L ATDADE R+ Y I GN F I NG L+ Sbjct: 1105 SSYEASVPEDIPEGHSILQLKATDADEGEFGRVWYRILHGNHGNNFRIHVSNGL-LMRGP 1163 Query: 427 QPLDFKQERRYVLTVSA--TDSGGRSDTAMVQINITDANNYAPVFENAPYT-ASVFEDAP 483 +PLD ++ +VL V A D G + V + + D N+ APVF Y+ + E A Sbjct: 1164 RPLDRERNSSHVLIVEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAG 1223 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 IGT+V+VV ATD D G + Y + S + +F I+ TG I T LD ET Sbjct: 1224 IGTSVIVVQATDRDSGDGGLVNYRILSGA--------EGKFEIDESTGLIITVNYLDYET 1275 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 + Y++ V+A D P V I++++ D F Y A I+E+ +GT + +V Sbjct: 1276 KTSYMMNVSATDQAPPFNQGFCSVYITLLNELDEAVQFSNASYEAAILENLALGTEIVRV 1335 Query: 604 GATDADVGLNGRIHYELD--PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 A D LN +I Y D + + F ID +GVI +DRE + L VA D Sbjct: 1336 QAYSID-NLN-QITYRFDAYTSTQAKALFKIDAITGVITVQGLVDREKGDFYTLTVVADD 1393 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFE-SDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 GG P STV V+I + D ND+ P F+ + I E+ P+G + ++A DPD G N Sbjct: 1394 GG-PKVDSTVKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVGQRVATVKAWDPDAGSNG 1452 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWND 777 V +S+ G+ + +F + T S E+ LD E Y L + A+ +PP D Sbjct: 1453 QVVFSLASGNIAGAFEIVTTNDS-IGEVFVARPLDREE-LDHYILQVVASDRGTPPRKKD 1510 Query: 778 VRVEILVTDVNDNAPVMKD---FQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSG 834 +++ + D+NDN PV++ + + N R D + L Y I G Sbjct: 1511 HILQVTILDINDNPPVIESPFGYNVSVNENVGGGTAVVQVRATDRDIGINSVLSYYITEG 1570 Query: 835 NNANLILLNETTGSMTLSP 853 N ++ +G + P Sbjct: 1571 NKDMTFRMDRISGEIATRP 1589 Score = 338 bits (831), Expect = 1e-90 Identities = 266/889 (29%), Positives = 409/889 (46%), Gaps = 75/889 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I +++ ND+ P+F Y S+ E + GT+VLT+ ATD D G EV Y Sbjct: 447 KITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFFS------ 500 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 +D D F +D +G ++ A LD E + R+T+ + A D Sbjct: 501 ---DD------------PDRFSLDKDTGLIMLIARLDYELIQRFTLTIIARDGGGE---- 541 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE-DISVTDNPVIAKIKATDADVGANSAIR 188 +T + +N++D NDN P F + Y ++ E + SVT + +++ATD D N+ I Sbjct: 542 -ETTGRVRINVLDVNDNVPTFQKDAYVGALRENEPSVTQ---LVRLRATDEDSPPNNQIT 597 Query: 189 YAIIGGN---TQMQFSIDSLSGDVSLVKTLDYEQVRS--YRLVIRAQDGGSPSRSNTTQL 243 Y+I+ + + S+ G +S+ + LDYEQ+ + L + A D G+P ++T + Sbjct: 598 YSIVSASAFGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPV 657 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 I + D NDN P F + SV EN+ G +++ + A D D Y Y+ Sbjct: 658 TIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDR----SREYGQESIIYSL 713 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG--GDPPRSATATXXXXXXXXXX 361 I+ RSG + T+ LDRET+++Y L+V A DG G ++ AT Sbjct: 714 EGSTQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNITLLDIND 773 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419 + Y + L E PP + V T+ A D D E+ L Y I N +S+ S G Sbjct: 774 NHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQPPNK--FYSLNSTTG 831 Query: 420 R-----GLITVAQPLDFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNYAPVFE 470 + ++ P + E + VS TD G + +A V +N+ D N+ P F+ Sbjct: 832 KIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLNDNDPTFQ 891 Query: 471 NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 N P+ A V E P G ++ V A D D G+N ++Y + V F+IN + Sbjct: 892 NLPFVAEVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRM-------PVGMPRMDFLINSSS 944 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590 G + T LDRE ++ Y L V A D G P+ S T+ + I V+DVND P F +Y ++ Sbjct: 945 GVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDETPTFFPAVYNVSV 1004 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650 ED V + TD DVGLN + Y + +G F + V+RT LDRE+ Sbjct: 1005 SEDVPREFRVVWLNCTDNDVGLNAELSYFI-TGGNVDGKFSVGYRDAVVRTVVGLDRETT 1063 Query: 651 ATHDLKAVAIDGGT--PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 A + L AID G + T V + + D+ND+ P+F + E+ P G +I + Sbjct: 1064 AAYMLILEAIDNGPVGKRHTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIPEGHSILQ 1123 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768 ++A D DEG V Y I G+ N+F + G + LD E + L++ Sbjct: 1124 LKATDADEGEFGRVWYRILHGNHGNNFRIHVSNG---LLMRGPRPLDRER-NSSHVLIVE 1179 Query: 769 AAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVT 824 A + P+ + VRV + V D+ND APV Q ++ +G V A D D Sbjct: 1180 AYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAGIGTSVIVVQATDRDSG 1239 Query: 825 D--KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 D + YRILSG ++E+TG + L+ M VS TD Sbjct: 1240 DGGLVNYRILSGAEGK-FEIDESTGLIITVNYLDYETKTSYMMNVSATD 1287 Score = 336 bits (825), Expect = 7e-90 Identities = 274/889 (30%), Positives = 419/889 (47%), Gaps = 83/889 (9%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASS-GTTVLTLKATDQDIGKNAEVEYTIELVT 66 H + ++D ND++P+F+ YE + EG + T+++T++A D D G N V Y I V Sbjct: 1619 HVYVTIVDENDNAPMFQQPHYEVLLDEGPDTLNTSLITIQALDLDEGPNGTVTYAI--VA 1676 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDRE-KVARYTVLVKATDQASP 125 + +N FRID G + LD E RYT++V ATDQ Sbjct: 1677 GNIVN-----------------TFRIDRHMGVITAAKELDYEISHGRYTLIVTATDQCPI 1719 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 +S RL+ST T+ VN+ D NDN P F + Y E P + A D D G N Sbjct: 1720 LSHRLTSTTTVLVNVNDINDNVPTF-PRDYE-GPFEVTEGQPGPRVWTFLAHDRDSGPNG 1777 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVK--TLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 + Y+I+ G+ +F I + G + + K LD E + Y L I A+D G P S+T + Sbjct: 1778 QVEYSIMDGDPLGEFVISPVEGVLRVRKDVELDRETIAFYNLTICARDRGMPPLSSTMLV 1837 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 I + D+NDN P ++SEN P+ + V A DAD G NA LT+ +T G Sbjct: 1838 GIRVLDINDNDPVLLNLPMNITISENSPVSSFVAHVLASDADSGCNARLTFNIT----AG 1893 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 N + I+ +G V + LDRE +Y+L ++ D + PR A Sbjct: 1894 NRERAFFINATTGIVTVNRPLDRERIPEYKLTISVKDNPENPRIARRDYDLLLIFLSDEN 1953 Query: 364 X---XFMPGQYEVELAEDEPPGTPVVTLT----ATDADED--NRLHYEITGGNTRGRFSI 414 F Y+ E+ E+ P GTP+ L A DAD+D + Y++ G + G F I Sbjct: 1954 DNHPLFTKSTYQAEVMENSPAGTPLTVLNGPILALDADQDIYAVVTYQLLGAQS-GLFDI 2012 Query: 415 TSQNGRGLITVAQPLDFKQER----RYVLTVSATDSGGRSDTAMVQINITDANNYAPVFE 470 S G++TV + +E L + A D G + TA + I I D N+ P F Sbjct: 2013 NSST--GVVTVRSGVIIDREAFSPPILELLLLAEDIGLLNSTAHLLITILDDNDNRPTFS 2070 Query: 471 NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 A T + E+ P G +VL V+ATD D G+N ++ Y + EA A +F+I+ T Sbjct: 2071 PATLTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRI------EAGA--QDRFLIHLVT 2122 Query: 531 GAITT-NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589 G I N +DRE Y LTV A D G LS T V I + D+ND+ P F + T + Sbjct: 2123 GVIRVGNATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDINDSRPEFLNPIQTVS 2182 Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYEL------DPKDR----EEGSFVIDPASGVI 639 ++E A GT ++ + A D D LN ++ Y + D DR +E +F ++ +G + Sbjct: 2183 VLESAEPGTVIANITAIDHD--LNPKLEYHIVGIVAKDDTDRLVPNQEDAFAVNINTGSV 2240 Query: 640 RTNKALDRESVATHDLKAVAIDGGTP-PQSSTVIVHIKIE----DINDSPPVFESDCLTF 694 ++RE VAT+++ ID + P+ S + + K+ D+ND+ P F+ +T+ Sbjct: 2241 MVKSPMNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNVLDVNDNTPQFKPFGITY 2300 Query: 695 Y---ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751 Y I E + GTT+ + A DPD+G N +V Y++ LE S +++ Sbjct: 2301 YMERILEGATPGTTLIAVAAVDPDKGLNGLVTYTLLDLVPPGYVQLE---DSSAGKVIAN 2357 Query: 752 VDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCF 808 +DYE +RA+ SPP ++ V + + D+NDN P+ ++D Sbjct: 2358 RTVDYEEVH-WLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPIFDQPSYQEAVFED-V 2415 Query: 809 PVGP-FGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 PVG V A DAD + G+ + +N TTG + + L+ Sbjct: 2416 PVGTIILTVTATDADSGNFALIEYSLGDGESKFAINPTTGDIYVLSSLD 2464 Score = 330 bits (811), Expect = 3e-88 Identities = 277/882 (31%), Positives = 411/882 (46%), Gaps = 62/882 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND+ P+F YEASV E G ++L LKATD D G+ V Y I L Sbjct: 1090 VTVLDVNDNRPIFLQSSYEASVPEDIPEGHSILQLKATDADEGEFGRVWYRI-------L 1142 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS-LDREKVARYTVLVKATDQASPVSDR 129 + FRI +G L+ LDRE+ + + ++V+A + Sbjct: 1143 HGNHGNN------------FRIHVSNGLLMRGPRPLDRERNSSHVLIVEAYNHDL---GP 1187 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYT-VSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 + S+ + V + D ND P F+++ Y+ + + E + + ++ ++ATD D G + Sbjct: 1188 MRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAGIGTSVIV--VQATDRDSGDGGLVN 1245 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y I+ G + +F ID +G + V LDYE SY + + A D P + I + Sbjct: 1246 YRILSG-AEGKFEIDESTGLIITVNYLDYETKTSYMMNVSATDQAPPFNQGFCSVYITLL 1304 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 + D A +F + ++ ++ EN+ +G IVRVQAY D +N ++TY D + Sbjct: 1305 NELDEAVQFSNASYEAAILENLALGTEIVRVQAYSIDN-LN-QITYRF-DAYTSTQAKAL 1361 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 ID +G + G +DRE Y L V A DGG S Sbjct: 1362 FKIDAITGVITVQGLVDREKGDFYTLTVVADDGGPKVDSTVKVYITVLDENDNSPRFDFT 1421 Query: 369 GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGR-GLITV 425 V + ED P G V T+ A D D + ++ + + GN G F I + N G + V Sbjct: 1422 SDSAVSIPEDCPVGQRVATVKAWDPDAGSNGQVVFSLASGNIAGAFEIVTTNDSIGEVFV 1481 Query: 426 AQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENA-PYTASVFEDA 482 A+PLD ++ Y+L V A+D G R ++Q+ I D N+ PV E+ Y SV E+ Sbjct: 1482 ARPLDREELDHYILQVVASDRGTPPRKKDHILQVTILDINDNPPVIESPFGYNVSVNENV 1541 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL-DR 541 GT V+ V ATD D+GIN+ ++Y ++ + D F ++ +G I T DR Sbjct: 1542 GGGTAVVQVRATDRDIGINSVLSYYITE-------GNKDMTFRMDRISGEIATRPAPPDR 1594 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA-LVGTSV 600 E S Y L T D G P+LS TT V +++VD NDN P+F+Q Y + E + TS+ Sbjct: 1595 ERQSFYHLVATVEDEGTPTLSATTHVYVTIVDENDNAPMFQQPHYEVLLDEGPDTLNTSL 1654 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE-SVATHDLKAVA 659 + A D D G NG + Y + +F ID GVI K LD E S + L A Sbjct: 1655 ITIQALDLDEGPNGTVTYAI-VAGNIVNTFRIDRHMGVITAAKELDYEISHGRYTLIVTA 1713 Query: 660 IDGG---TPPQSSTVIVHIKIEDINDSPPVFESDCL-TFYISENSPIGTTIGEIRAHDPD 715 D + +ST V + + DIND+ P F D F ++E P G + AHD D Sbjct: 1714 TDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEGPFEVTEGQP-GPRVWTFLAHDRD 1772 Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---P 772 GPN V YSI GD F + +G + V+LD E+ Y L I A P Sbjct: 1773 SGPNGQVEYSIMDGDPLGEFVISPVEGVLRVR--KDVELDRETIAF-YNLTICARDRGMP 1829 Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDAD--VTDKLQY 829 PL + + V I V D+NDN PV+ + + ++ PV F V A DAD +L + Sbjct: 1830 PLSSTMLVGIRVLDINDNDPVLLNLPMNITISENS-PVSSFVAHVLASDADSGCNARLTF 1888 Query: 830 RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 I +GN +N TTG +T++ L+ + +SV D Sbjct: 1889 NITAGNRERAFFINATTGIVTVNRPLDRERIPEYKLTISVKD 1930 Score = 327 bits (803), Expect = 3e-87 Identities = 273/868 (31%), Positives = 416/868 (47%), Gaps = 76/868 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I +L+ D + F YEA++ E + GT ++ ++A Y+I D L Sbjct: 1301 ITLLNELDEAVQFSNASYEAAILENLALGTEIVRVQA------------YSI-----DNL 1343 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N + + +F+ID +G + + +DREK YT+ V A D P ++ Sbjct: 1344 N-QITYRFDAYTSTQAKALFKIDAITGVITVQGLVDREKGDFYTLTVVA-DDGGP---KV 1398 Query: 131 SSTATIHVNIIDDNDNYPQFS-EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 ST +++ ++D+NDN P+F VS+ ED V +A +KA D D G+N + + Sbjct: 1399 DSTVKVYITVLDENDNSPRFDFTSDSAVSIPEDCPVGQR--VATVKAWDPDAGSNGQVVF 1456 Query: 190 AIIGGNTQMQFSI----DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 ++ GN F I DS+ G+V + + LD E++ Y L + A D G+P R L + Sbjct: 1457 SLASGNIAGAFEIVTTNDSI-GEVFVARPLDREELDHYILQVVASDRGTPPRKKDHILQV 1515 Query: 246 NIRDVNDNAPRFYTSL-FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 I D+NDN P + + SV+ENV G ++V+V+A D D G+N+ L+Y +T+ GN Sbjct: 1516 TILDINDNPPVIESPFGYNVSVNENVGGGTAVVQVRATDRDIGINSVLSYYITE----GN 1571 Query: 305 VDLPITIDPRSGWVYTS-GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 D+ +D SG + T DRE Q+ Y L+ T D G P SAT Sbjct: 1572 KDMTFRMDRISGEIATRPAPPDRERQSFYHLVATVEDEGTPTLSATTHVYVTIVDENDNA 1631 Query: 364 XXFMPGQYEVELAED-EPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGR 420 F YEV L E + T ++T+ A D DE + + Y I GN F I Sbjct: 1632 PMFQQPHYEVLLDEGPDTLNTSLITIQALDLDEGPNGTVTYAIVAGNIVNTFRIDRH--M 1689 Query: 421 GLITVAQPLDFK-QERRYVLTVSATD-----SGGRSDTAMVQINITDANNYAPVFEN--- 471 G+IT A+ LD++ RY L V+ATD S + T V +N+ D N+ P F Sbjct: 1690 GVITAAKELDYEISHGRYTLIVTATDQCPILSHRLTSTTTVLVNVNDINDNVPTFPRDYE 1749 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 P+ V E P G V A D D G N Q+ YS+ + + + +FVI+P G Sbjct: 1750 GPF--EVTEGQP-GPRVWTFLAHDRDSGPNGQVEYSI---MDGDPLG----EFVISPVEG 1799 Query: 532 AITTNK--LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589 + K LDRET++ Y LT+ ARD G+P LS T V I V+D+NDN+PV Sbjct: 1800 VLRVRKDVELDRETIAFYNLTICARDRGMPPLSSTMLVGIRVLDINDNDPVLLNLPMNIT 1859 Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES 649 I E++ V + V+ V A+DAD G N R+ + + +RE +F I+ +G++ N+ LDRE Sbjct: 1860 ISENSPVSSFVAHVLASDADSGCNARLTFNITAGNRER-AFFINATTGIVTVNRPLDRER 1918 Query: 650 VATHDLKAVAIDGGTPPQSSTV---IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706 + + L D P+ + ++ I + D ND+ P+F + ENSP GT + Sbjct: 1919 IPEYKLTISVKDNPENPRIARRDYDLLLIFLSDENDNHPLFTKSTYQAEVMENSPAGTPL 1978 Query: 707 ----GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762 G I A D D+ AVV Y + G S F + + G ++D + SP Sbjct: 1979 TVLNGPILALDADQDIYAVVTYQLLGAQ-SGLFDINSSTGVVTVRSGVIIDREAFSP-PI 2036 Query: 763 YELVIRAASPPLWNDV-RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDA 821 EL++ A L N + I + D NDN P + + ++C P +V A D Sbjct: 2037 LELLLLAEDIGLLNSTAHLLITILDDNDNRPTFSPATLTVHLLENCPPGFSVLQVTATDE 2096 Query: 822 D--VTDKLQYRILSGNNANLILLNETTG 847 D + +L YRI +G + L++ TG Sbjct: 2097 DSGLNGELVYRIEAGAQ-DRFLIHLVTG 2123 Score = 318 bits (780), Expect = 2e-84 Identities = 267/872 (30%), Positives = 418/872 (47%), Gaps = 77/872 (8%) Query: 11 INVLDCNDHSPVFEMQQYEA-SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 + V D ND +PVF QQY +RE A GT+V+ ++ATD+D G V Y I Sbjct: 1196 VYVEDINDEAPVFTQQQYSRLGLRETAGIGTSVIVVQATDRDSGDGGLVNYRI------- 1248 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + F ID +G ++T LD E Y + V ATDQA P + Sbjct: 1249 -------------LSGAEGKFEIDESTGLIITVNYLDYETKTSYMMNVSATDQAPPFNQG 1295 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S +++ ++++ D QFS +Y ++ E++++ I +++A D R+ Sbjct: 1296 FCS---VYITLLNELDEAVQFSNASYEAAILENLALGTE--IVRVQAYSIDNLNQITYRF 1350 Query: 190 -AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 A + F ID+++G +++ +D E+ Y L + A DGG P +T ++ I + Sbjct: 1351 DAYTSTQAKALFKIDAITGVITVQGLVDREKGDFYTLTVVADDGG-PKVDSTVKVYITVL 1409 Query: 249 DVNDNAPRF-YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 D NDN+PRF +TS S+ E+ P+G + V+A+D D G N ++ +++ + G ++ Sbjct: 1410 DENDNSPRFDFTSDSAVSIPEDCPVGQRVATVKAWDPDAGSNGQVVFSLASGNIAGAFEI 1469 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF- 366 +T + G V+ + LDRE Y L V A+D G PPR Sbjct: 1470 -VTTNDSIGEVFVARPLDREELDHYILQVVASDRGTPPRKKDHILQVTILDINDNPPVIE 1528 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLIT 424 P Y V + E+ GT VV + ATD D ++ L Y IT GN F + +G + T Sbjct: 1529 SPFGYNVSVNENVGGGTAVVQVRATDRDIGINSVLSYYITEGNKDMTFRMDRISGE-IAT 1587 Query: 425 VAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 P D +++ Y L + D G S T V + I D N+ AP+F+ P+ + ++ Sbjct: 1588 RPAPPDRERQSFYHLVATVEDEGTPTLSATTHVYVTIVDENDNAPMFQQ-PHYEVLLDEG 1646 Query: 483 P--IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 P + T+++ + A D D G N +TY++ ++ V F I+ G IT K LD Sbjct: 1647 PDTLNTSLITIQALDLDEGPNGTVTYAI---VAGNIV----NTFRIDRHMGVITAAKELD 1699 Query: 541 RETMSG-YLLTVTARDGGVPSLS----DTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 E G Y L VTA D P LS TT V ++V D+NDN P F + + + Sbjct: 1700 YEISHGRYTLIVTATDQ-CPILSHRLTSTTTVLVNVNDINDNVPTFPRDYEGPFEVTEGQ 1758 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK--ALDRESVATH 653 G V A D D G NG++ Y + D G FVI P GV+R K LDRE++A + Sbjct: 1759 PGPRVWTFLAHDRDSGPNGQVEYSIMDGD-PLGEFVISPVEGVLRVRKDVELDRETIAFY 1817 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713 +L A D G PP SST++V I++ DIND+ PV + + ISENSP+ + + + A D Sbjct: 1818 NLTICARDRGMPPLSSTMLVGIRVLDINDNDPVLLNLPMNITISENSPVSSFVAHVLASD 1877 Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM-VDLDYESPRKKYELVIRAASP 772 D G NA + ++I G+ +F + G +VT+ LD E +Y+L I Sbjct: 1878 ADSGCNARLTFNITAGNRERAFFINATTG-----IVTVNRPLDRER-IPEYKLTISVKDN 1931 Query: 773 PLWNDVR------VEILVTDVNDNAPVM--KDFQI-IFNNYKDCFPV----GPFGRVPAY 819 P + + I ++D NDN P+ +Q + N P+ GP + A Sbjct: 1932 PENPRIARRDYDLLLIFLSDENDNHPLFTKSTYQAEVMENSPAGTPLTVLNGPILALDA- 1990 Query: 820 DADVTDKLQYRILSGNNANLILLNETTGSMTL 851 D D+ + Y++L G + L +N +TG +T+ Sbjct: 1991 DQDIYAVVTYQLL-GAQSGLFDINSSTGVVTV 2021 Score = 305 bits (750), Expect = 8e-81 Identities = 256/901 (28%), Positives = 414/901 (45%), Gaps = 58/901 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +INVLD ND+ P F+ Y ++RE S T ++ L+ATD+D N ++ Y+I V+A Sbjct: 548 RINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSI--VSASA 605 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTV--LVKATDQASPVS 127 D+ +G G + LD E+++ + V A D +P Sbjct: 606 FG-------------SYFDISLYEG-YGVISVSRPLDYEQISNGLIYLTVMAMDAGNP-- 649 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 L+ST + + + D+NDN P FS+ Y VSV E+I + + ATD D Sbjct: 650 -PLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMA--GATVLFLNATDLDRSREYGQ 706 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 I QF I++ SG+++ LD E Y L++RA DGG T +NI Sbjct: 707 ESIIYSLEGSTQFRINARSGEITTTSLLDRETKSEYILIVRAVDGGVGHNQKTGIATVNI 766 Query: 248 R--DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM--TDKDYTG 303 D+NDN P + + + ++ E P + V A D D G N L Y++ +K Y+ Sbjct: 767 TLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQPPNKFYSL 826 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT--ATXXXXXXXXXX 361 N I + E + +++V+ TD G PP AT AT Sbjct: 827 N-STTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATVFVNLLDLND 885 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNG 419 F + E+ E P G + + A D DE + + Y + G R F I S + Sbjct: 886 NDPTFQNLPFVAEVLEGIPAGVSIYQVVAIDLDEGLNGLVSYRMPVGMPRMDFLINSSS- 944 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477 G++ LD ++ Y L V A+D+G +S T+ + I++ D N+ P F A Y S Sbjct: 945 -GVVVTTTELDRERIAEYQLRVVASDAGTPTKSSTSTLTIHVLDVNDETPTFFPAVYNVS 1003 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 V ED P V+ ++ TD+DVG+NA+++Y ++ + D +F + + + T Sbjct: 1004 VSEDVPREFRVVWLNCTDNDVGLNAELSYFITG-------GNVDGKFSVGYRDAVVRTVV 1056 Query: 538 LLDRETMSGYLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 LDRET + Y+L + A D G + T V ++V+DVNDN P+F Q Y A++ ED Sbjct: 1057 GLDRETTAAYMLILEAIDNGPVGKRHTGTATVFVTVLDVNDNRPIFLQSSYEASVPEDIP 1116 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI-RTNKALDRESVATHD 654 G S+ Q+ ATDAD G GR+ Y + +F I ++G++ R + LDRE ++H Sbjct: 1117 EGHSILQLKATDADEGEFGRVWYRI-LHGNHGNNFRIHVSNGLLMRGPRPLDRERNSSHV 1175 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF-ESDCLTFYISENSPIGTTIGEIRAHD 713 L A + P S+V V + +EDIND PVF + + E + IGT++ ++A D Sbjct: 1176 LIVEAYNHDLGPMRSSVRVIVYVEDINDEAPVFTQQQYSRLGLRETAGIGTSVIVVQATD 1235 Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP 773 D G +V+Y I G + F ++ G ++T+ LDYE+ V P Sbjct: 1236 RDSGDGGLVNYRILSGAE-GKFEIDESTGL----IITVNYLDYETKTSYMMNVSATDQAP 1290 Query: 774 LWNDVRVEILVTDVN--DNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRI 831 +N + +T +N D A + ++ RV AY D +++ YR Sbjct: 1291 PFNQGFCSVYITLLNELDEAVQFSNASYEAAILENLALGTEIVRVQAYSIDNLNQITYRF 1350 Query: 832 ---LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLIT 888 S L ++ TG +T+ ++ T+ V DG ++ + +++ + ++ Sbjct: 1351 DAYTSTQAKALFKIDAITGVITVQGLVDREKGDFYTLTVVADDGGPKVDSTVKVYITVLD 1410 Query: 889 E 889 E Sbjct: 1411 E 1411 Score = 295 bits (725), Expect = 9e-78 Identities = 238/779 (30%), Positives = 370/779 (47%), Gaps = 71/779 (9%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 D ND P F SV E A GT + + A D D+ N ++EY I + A +D Sbjct: 2166 DINDSRPEFLNPIQTVSVLESAEPGTVIANITAIDHDL--NPKLEYHIVGIVAK----DD 2219 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSST- 133 +D F ++ +G+++ ++ ++RE VA Y V + D AS + +R S Sbjct: 2220 TDRLVPNQ----EDAFAVNINTGSVMVKSPMNRELVATYEVTLSVIDNASDLPERSVSVP 2275 Query: 134 -ATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS-VTDNPVIAKIKATDADVGANSAIRYAI 191 A + VN++D NDN PQF T ++ + T + + A D D G N + Y + Sbjct: 2276 NAKLTVNVLDVNDNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGLNGLVTYTL 2335 Query: 192 IG----GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 + G Q++ DS +G V +T+DYE+V +RA D GSP R+ + + I Sbjct: 2336 LDLVPPGYVQLE---DSSAGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEI 2392 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 D+NDN P F +QE+V E+VP+G I+ V A DAD G A + Y++ G+ + Sbjct: 2393 VDINDNNPIFDQPSYQEAVFEDVPVGTIILTVTATDADSGNFALIEYSL------GDGES 2446 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG-GDPP---RSATATXXXXXXXXXXXX 363 I+P +G +Y LDRE + Y L A D GD R + Sbjct: 2447 KFAINPTTGDIYVLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCR 2506 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRG 421 F Q+ + E+EP GT V+T+ ATD DE + L Y + G F + + G Sbjct: 2507 PQFSKPQFSTSVYENEPAGTSVITMMATDQDEGPNGELTYSLEGPGVEA-FHVDMDS--G 2563 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAP--YTAS 477 L+T +PL + ++ LTV ATD G T M+ + + D N+ PVF P Sbjct: 2564 LVTTQRPL--QSYEKFSLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPVFVRPPNGTILH 2621 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 + E+ P+ + V V ATD D G+N + YS N + F+I+P +G I T + Sbjct: 2622 IREEIPLRSNVYEVYATDKDEGLNGAVRYSFLKTAGN----RDWEFFIIDPISGLIQTAQ 2677 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTD-VEISVVDVNDNEPVF------KQQLYTANI 590 LDRE+ + Y L + A D G P +T +++++ D++DNEP+F Q + Sbjct: 2678 RLDRESQAVYSLILVASDLGQPVPYETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTV 2737 Query: 591 MEDALVGTSVSQV-GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD--R 647 E + GT V V GA DAD G N ++Y + EE +F + P G + + LD R Sbjct: 2738 PEHSPRGTLVGNVTGAVDADEGPNAIVYYFI-AAGNEEKNFHLQP-DGCLLVLRDLDRER 2795 Query: 648 ESVATHDLKAVAIDGGTPPQ--SSTV---------IVHIKIEDINDSPPVFESDCLTFYI 696 E++ + +KA + TPP+ S T+ V + +EDIND PP F T + Sbjct: 2796 EAIFSFIVKASSNRSWTPPRGPSPTLDLVADLTLQEVRVVLEDINDQPPRFTKAEYTAGV 2855 Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755 + ++ +G+ + ++ A D D G N++V YSI + F D ++ TM +D Sbjct: 2856 ATDAKVGSELIQVLALDADIGNNSLVFYSILA---IHYFRALANDSEDVGQVFTMGSMD 2911 Score = 287 bits (703), Expect = 4e-75 Identities = 247/820 (30%), Positives = 373/820 (45%), Gaps = 85/820 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I VLD ND+ PV ++ E + + V + A+D D G NA + + I TA Sbjct: 1839 IRVLDINDNDPVLLNLPMNITISENSPVSSFVAHVLASDADSGCNARLTFNI---TAG-- 1893 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N E A F I+ +G + LDRE++ Y + + D +P + R+ Sbjct: 1894 NRERA--------------FFINATTGIVTVNRPLDRERIPEYKLTISVKD--NPENPRI 1937 Query: 131 SSTA--TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIA---KIKATDADVGANS 185 + + + + D+NDN+P F++ TY V E+ S P+ I A DAD + Sbjct: 1938 ARRDYDLLLIFLSDENDNHPLFTKSTYQAEVMEN-SPAGTPLTVLNGPILALDADQDIYA 1996 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVK--TLDYEQVRS--YRLVIRAQDGGSPSRSNTT 241 + Y ++G + + F I+S +G V++ +D E L++ A+D G ++T Sbjct: 1997 VVTYQLLGAQSGL-FDINSSTGVVTVRSGVIIDREAFSPPILELLLLAEDIGL--LNSTA 2053 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 LLI I D NDN P F + + EN P G+S+++V A D D G+N EL Y + Sbjct: 2054 HLLITILDDNDNRPTFSPATLTVHLLENCPPGFSVLQVTATDEDSGLNGELVYRIEAGAQ 2113 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 + +T R G + +DRE Q Y+L V ATD G P S TA Sbjct: 2114 DRFLIHLVTGVIRVG----NATIDREEQESYRLTVVATDRGTVPLSGTAIVTILIDDIND 2169 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITG-----------GNTRG 410 F+ V + E PGT + +TA D D + +L Y I G N Sbjct: 2170 SRPEFLNPIQTVSVLESAEPGTVIANITAIDHDLNPKLEYHIVGIVAKDDTDRLVPNQED 2229 Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG----RS---DTAMVQINITDAN 463 F++ G + V P++ + Y +T+S D+ RS A + +N+ D N Sbjct: 2230 AFAVNINTGS--VMVKSPMNRELVATYEVTLSVIDNASDLPERSVSVPNAKLTVNVLDVN 2287 Query: 464 NYAPVFEN---APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520 + P F+ Y + E A GTT++ V+A D D G+N +TY+L + V Sbjct: 2288 DNTPQFKPFGITYYMERILEGATPGTTLIAVAAVDPDKGLNGLVTYTLLDLVPPGYVQLE 2347 Query: 521 DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580 D G + N+ +D E + TV A D G P + V + +VD+NDN P+ Sbjct: 2348 DSS------AGKVIANRTVDYEEVHWLNFTVRASDNGSPPRAAEIPVYLEIVDINDNNPI 2401 Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640 F Q Y + ED VGT + V ATDAD G I Y L E F I+P +G I Sbjct: 2402 FDQPSYQEAVFEDVPVGTIILTVTATDADSGNFALIEYSLGDG---ESKFAINPTTGDIY 2458 Query: 641 TNKALDRESVATHDLKAVAIDG----GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696 +LDRE + L A+A D + + ++V V I++ D+ND P F + + Sbjct: 2459 VLSSLDREKKDHYILTALAKDNPGDVASNRRENSVQVVIQVLDVNDCRPQFSKPQFSTSV 2518 Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756 EN P GT++ + A D DEGPN + YS++G +F ++ G LVT Sbjct: 2519 YENEPAGTSVITMMATDQDEGPNGELTYSLEG-PGVEAFHVDMDSG-----LVT-TQRPL 2571 Query: 757 ESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPV 793 +S +K+ L + A PPLW + + V DVNDN PV Sbjct: 2572 QS-YEKFSLTVVATDGGEPPLWGTTMLLVEVIDVNDNRPV 2610 Score = 273 bits (669), Expect = 5e-71 Identities = 250/876 (28%), Positives = 390/876 (44%), Gaps = 71/876 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND++P F Q Y + E GT + + ATD D+G V Y+ + Sbjct: 120 IQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNATDPDLGAGGSVLYSFQ------- 172 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P F ID G + LD E Y + V ATDQ + L Sbjct: 173 -PPS-------------QFFAIDSARGIVTVIRELDYETTQAYQLTVNATDQDK--TRPL 216 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+ A + + I D D P F Y+ ++ E + I A D D G I Y Sbjct: 217 STLANLAIIITDVQDMDPIFINLPYSTNIYEHSP--PGTTVRIITAIDQDKGRPRGIGYT 274 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQ-VRSYRLVIRAQ-----DGGSPSRSN-TTQL 243 I+ GNT F++D +SG ++L LD E + S+ ++ + D +PS + TT Sbjct: 275 IVSGNTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSDATVTTTF 334 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSI-VRVQAYDADE--GVNAELTYTMTDKD 300 I + D+NDNAP F +S + +++E +G+++ + +Q D DE G+N+ + + Sbjct: 335 NILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDENLGLNSMFEVYLVGNN 394 Query: 301 YTGNVDLPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 + P ++ ++ + + LD ET +Y + A + P A Sbjct: 395 SHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESV-PDHVGYAKVKITLINE 453 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG 419 F Y + L E+ GT V+T+ ATD D + RFS+ G Sbjct: 454 NDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFFSDDPDRFSLDKDTG 513 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479 LI + LD++ +R+ LT+ A D GG T V+IN+ D N+ P F+ Y ++ Sbjct: 514 --LIMLIARLDYELIQRFTLTIIARDGGGEETTGRVRINVLDVNDNVPTFQKDAYVGALR 571 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E+ P T ++ + ATD D N QITYS+ +S A + + G I+ ++ L Sbjct: 572 ENEPSVTQLVRLRATDEDSPPNNQITYSI---VSASAFGSY-FDISLYEGYGVISVSRPL 627 Query: 540 DRETMSGYL--LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 D E +S L LTV A D G P L+ T V I V D NDN P F + Y +++E+ + G Sbjct: 628 DYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAG 687 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGS--FVIDPASGVIRTNKALDRESVATHDL 655 +V + ATD D R + + EGS F I+ SG I T LDRE+ + + L Sbjct: 688 ATVLFLNATDLD---RSREYGQESIIYSLEGSTQFRINARSGEITTTSLLDRETKSEYIL 744 Query: 656 KAVAIDGGTPPQSSTVI--VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713 A+DGG T I V+I + DIND+ P ++ + E +P + + + A D Sbjct: 745 IVRAVDGGVGHNQKTGIATVNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVD 804 Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP--------RKKYEL 765 PD G N + YSI+ + +SL + G + T LD E+P RK Sbjct: 805 PDLGENGTLVYSIQ--PPNKFYSLNSTTGKIR---TTHAMLDRENPDPHEAELMRKIVVS 859 Query: 766 VIRAASPPL--WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD 822 V PPL + V + + D+NDN P ++ + + P G +V A D D Sbjct: 860 VTDCGRPPLKATSSATVFVNLLDLNDNDPTFQNLPFV-AEVLEGIPAGVSIYQVVAIDLD 918 Query: 823 --VTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 + + YR+ G L+N ++G + + +L+ Sbjct: 919 EGLNGLVSYRMPVGMPRMDFLINSSSGVVVTTTELD 954 Score = 269 bits (659), Expect = 9e-70 Identities = 254/873 (29%), Positives = 397/873 (45%), Gaps = 85/873 (9%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F ++ +G + R LDRE + +TV +D + T +++ + D NDN P Sbjct: 78 FAVEPDTGVVWLRQPLDRETKSEFTVEFSVSDHQGVI------TRKVNIQVGDVNDNAPT 131 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209 F + Y+V + E+ V P+ + ATD D+GA ++ Y+ F+IDS G V Sbjct: 132 FHNQPYSVRIPENTPV-GTPIFI-VNATDPDLGAGGSVLYSF--QPPSQFFAIDSARGIV 187 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT-TQLLINIRDVNDNAPRFYTSLFQESVSE 268 ++++ LDYE ++Y+L + A D +T L I I DV D P F + ++ E Sbjct: 188 TVIRELDYETTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYE 247 Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328 + P G ++ + A D D+G + YT+ +GN + +D SG + +G LDRE Sbjct: 248 HSPPGTTVRIITAIDQDKGRPRGIGYTIV----SGNTNSIFALDYISGVLTLNGLLDREN 303 Query: 329 ---QAKYQLLVTATDGGD--PPRSATATXXXXXXXXXXXXXX--FMPGQYEVELAEDEPP 381 + L V T+ D P AT T F +Y V + E Sbjct: 304 PLYSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQV 363 Query: 382 GTPV-VTLTATDADEDNRLH--YEI-TGGNTRGRFSI--TSQNGRG--LITVAQPLDFKQ 433 G + + + D DE+ L+ +E+ GN F I TS G+ I VA PLD++ Sbjct: 364 GFALPLFIQVVDKDENLGLNSMFEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYET 423 Query: 434 ERRYVLTVSATDS-GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492 RY + A +S A V+I + + N+ P+F Y S++E+ +GT+VL V Sbjct: 424 VDRYDFDLFANESVPDHVGYAKVKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVL 483 Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552 ATD+D G +++Y S + +F ++ TG I LD E + + LT+ Sbjct: 484 ATDNDAGTFGEVSYFFSDD---------PDRFSLDKDTGLIMLIARLDYELIQRFTLTII 534 Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612 ARDGG T V I+V+DVNDN P F++ Y + E+ T + ++ ATD D Sbjct: 535 ARDGG--GEETTGRVRINVLDVNDNVPTFQKDAYVGALRENEPSVTQLVRLRATDEDSPP 592 Query: 613 NGRIHYELDPKDREEGSFVID--PASGVIRTNKALDRESVATH--DLKAVAIDGGTPPQS 668 N +I Y + F I GVI ++ LD E ++ L +A+D G PP + Sbjct: 593 NNQITYSIVSASAFGSYFDISLYEGYGVISVSRPLDYEQISNGLIYLTVMAMDAGNPPLN 652 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE----GPNAVVHY 724 STV V I++ D ND+PP F + EN G T+ + A D D G +++ Y Sbjct: 653 STVPVTIEVFDENDNPPTFSKPAYFVSVVENIMAGATVLFLNATDLDRSREYGQESII-Y 711 Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR----- 779 S++G S F + R G E+ T LD E+ + +Y L++RA + ++ + Sbjct: 712 SLEG---STQFRINARSG----EITTTSLLDRET-KSEYILIVRAVDGGVGHNQKTGIAT 763 Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNNA 837 V I + D+NDN P KD N + P V A D D+ + L Y I N Sbjct: 764 VNITLLDINDNHPTWKDAPYYINLVEMTPPDSDVTTVVAVDPDLGENGTLVYSIQPPN-- 821 Query: 838 NLILLNETTGSM-TLSPQLNTNVPK------LATMEVSVTD-GVNEIKAMMQLSVRLITE 889 LN TTG + T L+ P + + VSVTD G +KA +V Sbjct: 822 KFYSLNSTTGKIRTTHAMLDRENPDPHEAELMRKIVVSVTDCGRPPLKATSSATV----- 876 Query: 890 EMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAA 922 +N + + ND T + P + ++G+ A Sbjct: 877 --FVNLLDLNDNDPTFQNL--PFVAEVLEGIPA 905 Score = 220 bits (538), Expect = 4e-55 Identities = 193/650 (29%), Positives = 279/650 (42%), Gaps = 49/650 (7%) Query: 167 DNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLV 226 D PV + + A N + + + G F+++ +G V L + LD E + + Sbjct: 45 DTPVGSSVTQLLAQDMDNDPLVFGVSGEEASRFFAVEPDTGVVWLRQPLDRETKSEFTVE 104 Query: 227 IRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE 286 D T ++ I + DVNDNAP F+ + + EN P+G I V A D D Sbjct: 105 FSVSDHQGVI---TRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNATDPDL 161 Query: 287 GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-P 345 G + Y+ ID G V +LD ET YQL V ATD P Sbjct: 162 GAGGSVLYSFQPPSQF------FAIDSARGIVTVIRELDYETTQAYQLTVNATDQDKTRP 215 Query: 346 RSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI 403 S A F+ Y + E PPGT V +TA D D+ + Y I Sbjct: 216 LSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRIITAIDQDKGRPRGIGYTI 275 Query: 404 TGGNTRGRFSITSQNG----RGLITVAQPLDFKQERRYVLTVSAT---DSGGRSD---TA 453 GNT F++ +G GL+ PL ++LTV T D SD T Sbjct: 276 VSGNTNSIFALDYISGVLTLNGLLDRENPL---YSHGFILTVKGTELNDDRTPSDATVTT 332 Query: 454 MVQINITDANNYAPVFENAPYTASVFEDAPIGTTV-LVVSATDSDVGINAQITYSLSSEI 512 I + D N+ AP F ++ Y+ ++ E A +G + L + D D + L+S Sbjct: 333 TFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDENL------GLNSMF 386 Query: 513 SNEAVAHHDQQFVINPQTG------AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566 V ++ F+I+P + I LD ET+ Y + A + VP Sbjct: 387 EVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANE-SVPDHVGYAK 445 Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDR 625 V+I++++ NDN P+F Q LY ++ E+ VGTSV V ATD D G G + Y D DR Sbjct: 446 VKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFFSDDPDR 505 Query: 626 EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685 F +D +G+I LD E + L +A DGG + +T V I + D+ND+ P Sbjct: 506 ----FSLDKDTGLIMLIARLDYELIQRFTLTIIARDGG--GEETTGRVRINVLDVNDNVP 559 Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS-FSLETRQGSD 744 F+ D + EN P T + +RA D D PN + YSI S F + +G Sbjct: 560 TFQKDAYVGALRENEPSVTQLVRLRATDEDSPPNNQITYSIVSASAFGSYFDISLYEGYG 619 Query: 745 KAELVTMVDLDYESPRKKYELVIR--AASPPLWNDVRVEILVTDVNDNAP 792 + +D + S Y V+ A +PPL + V V I V D NDN P Sbjct: 620 VISVSRPLDYEQISNGLIYLTVMAMDAGNPPLNSTVPVTIEVFDENDNPP 669 Score = 185 bits (450), Expect = 2e-44 Identities = 167/566 (29%), Positives = 258/566 (45%), Gaps = 60/566 (10%) Query: 257 FYTSLFQES---VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313 F+T+ F ++ +SE+ P+G S+ ++ A D D N L + ++ ++ ++P Sbjct: 30 FFTNHFFDTYLLISEDTPVGSSVTQLLAQDMD---NDPLVFGVSGEE----ASRFFAVEP 82 Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373 +G V+ LDRET++++ + + + D T F Y V Sbjct: 83 DTGVVWLRQPLDRETKSEFTVEFSVS---DHQGVITRKVNIQVGDVNDNAPTFHNQPYSV 139 Query: 374 ELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ-----NGRGLITVAQP 428 + E+ P GTP+ + ATD D GG+ F SQ + RG++TV + Sbjct: 140 RIPENTPVGTPIFIVNATDPDLG-------AGGSVLYSFQPPSQFFAIDSARGIVTVIRE 192 Query: 429 LDFKQERRYVLTVSATDSGGR---SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 LD++ + Y LTV+ATD S A + I ITD + P+F N PY+ +++E +P G Sbjct: 193 LDYETTQAYQLTVNATDQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPG 252 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET-- 543 TTV +++A D D G I Y++ S +N F ++ +G +T N LLDRE Sbjct: 253 TTVRIITAIDQDKGRPRGIGYTIVSGNTNSI-------FALDYISGVLTLNGLLDRENPL 305 Query: 544 -MSGYLLTVTA---RDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 G++LTV D PS + TT I V+D+NDN P F Y+ I E A VG Sbjct: 306 YSHGFILTVKGTELNDDRTPSDATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGF 365 Query: 599 SVS---QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV------IRTNKALDRES 649 ++ QV D ++GLN +E+ F+I P S IR LD E+ Sbjct: 366 ALPLFIQVVDKDENLGLNSM--FEVYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYET 423 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 V +D A + P V I + + ND+ P+F + EN +GT++ + Sbjct: 424 VDRYDFDLFA-NESVPDHVGYAKVKITLINENDNRPIFSQPLYNISLYENVTVGTSVLTV 482 Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 A D D G V Y DD + FSL+ D ++ + LDYE ++ +I Sbjct: 483 LATDNDAGTFGEVSYFF--SDDPDRFSLD----KDTGLIMLIARLDYELIQRFTLTIIAR 536 Query: 770 ASPPLWNDVRVEILVTDVNDNAPVMK 795 RV I V DVNDN P + Sbjct: 537 DGGGEETTGRVRINVLDVNDNVPTFQ 562 Score = 175 bits (425), Expect = 2e-41 Identities = 143/514 (27%), Positives = 233/514 (45%), Gaps = 27/514 (5%) Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434 ++ED P G+ V L A D D D L + ++G F++ G ++ + QPLD + + Sbjct: 42 ISEDTPVGSSVTQLLAQDMDNDP-LVFGVSGEEASRFFAVEPDTG--VVWLRQPLDRETK 98 Query: 435 RRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494 + + S +D G T V I + D N+ AP F N PY+ + E+ P+GT + +V+AT Sbjct: 99 SEFTVEFSVSDHQGVI-TRKVNIQVGDVNDNAPTFHNQPYSVRIPENTPVGTPIFIVNAT 157 Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554 D D+G + YS Q F I+ G +T + LD ET Y LTV A Sbjct: 158 DPDLGAGGSVLYSFQPP---------SQFFAIDSARGIVTVIRELDYETTQAYQLTVNAT 208 Query: 555 D-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613 D LS ++ I + DV D +P+F Y+ NI E + GT+V + A D D G Sbjct: 209 DQDKTRPLSTLANLAIIITDVQDMDPIFINLPYSTNIYEHSPPGTTVRIITAIDQDKGRP 268 Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES-VATH----DLKAVAIDGGTPPQS 668 I Y + F +D SGV+ N LDRE+ + +H +K ++ P Sbjct: 269 RGIGYTI-VSGNTNSIFALDYISGVLTLNGLLDRENPLYSHGFILTVKGTELNDDRTPSD 327 Query: 669 STVIV--HIKIEDINDSPPVFESDCLTFYISENSPIGTTIG-EIRAHDPDE--GPNAVVH 723 +TV +I + DIND+ P F S + I+E + +G + I+ D DE G N++ Sbjct: 328 ATVTTTFNILVIDINDNAPEFNSSEYSVAITELAQVGFALPLFIQVVDKDENLGLNSMFE 387 Query: 724 YSIKGGDDSNSFSLETR-QGSDKAELVTMVDLDYES-PRKKYELVIRAASPPLWNDVRVE 781 + G + + T QG + + LDYE+ R ++L + P +V+ Sbjct: 388 VYLVGNNSHHFIISPTSVQGKADIRIRVAIPLDYETVDRYDFDLFANESVPDHVGYAKVK 447 Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLIL 841 I + + NDN P+ + Y++ V A D D + ++ + Sbjct: 448 ITLINENDNRPIFSQPLYNISLYENVTVGTSVLTVLATDNDAGTFGEVSYFFSDDPDRFS 507 Query: 842 LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE 875 L++ TG + L +L+ + + T+ + DG E Sbjct: 508 LDKDTGLIMLIARLDYELIQRFTLTIIARDGGGE 541 Score = 89.4 bits (212), Expect = 1e-15 Identities = 82/304 (26%), Positives = 131/304 (43%), Gaps = 35/304 (11%) Query: 11 INVLDCNDHSPVFEMQQYEA--SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68 + V+D ND+ PVF +RE + V + ATD+D G N V Y+ L TA Sbjct: 2599 VEVIDVNDNRPVFVRPPNGTILHIREEIPLRSNVYEVYATDKDEGLNGAVRYSF-LKTAG 2657 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 + E F ID SG + T LDRE A Y++++ A+D PV Sbjct: 2658 NRDWE---------------FFIIDPISGLIQTAQRLDRESQAVYSLILVASDLGQPVPY 2702 Query: 129 RLSSTATIHVNIIDDNDNY---PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 + + IDDN+ P Y + + S V A DAD G N+ Sbjct: 2703 ETMQPLQVALEDIDDNEPLFVRPPKGSPQYQLLTVPEHSPRGTLVGNVTGAVDADEGPNA 2762 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD--------GGSPSR 237 + Y I GN + F + G + +++ LD E+ + +++A G SP+ Sbjct: 2763 IVYYFIAAGNEEKNFHLQP-DGCLLVLRDLDREREAIFSFIVKASSNRSWTPPRGPSPTL 2821 Query: 238 SNTTQLLIN-----IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292 L + + D+ND PRF + + V+ + +G +++V A DAD G N+ + Sbjct: 2822 DLVADLTLQEVRVVLEDINDQPPRFTKAEYTAGVATDAKVGSELIQVLALDADIGNNSLV 2881 Query: 293 TYTM 296 Y++ Sbjct: 2882 FYSI 2885 >UniRef50_Q6V1P9 Cluster: Dachsous-2; n=9; Eutheria|Rep: Dachsous-2 - Homo sapiens (Human) Length = 2916 Score = 352 bits (866), Expect = 7e-95 Identities = 267/881 (30%), Positives = 420/881 (47%), Gaps = 57/881 (6%) Query: 1 MSVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIG-KNAEVE 59 +S+ + I+V D NDHSP F+ + SV E GT V A D D N+ ++ Sbjct: 1033 LSLSSTVFLSIDVEDQNDHSPSFQDELIVISVEENVPIGTLVYVFNAKDDDGSFLNSRIQ 1092 Query: 60 YTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKA 119 Y IE T NP F I G L+T + LDRE + + V A Sbjct: 1093 YYIESHNPGT-NP-----------------FLIHPSFGTLVTVSRLDRESIPTVILTVTA 1134 Query: 120 TDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA 179 +DQA V+DR + T + I+D ND+ P F V ED++V ++ I A D Sbjct: 1135 SDQAVNVTDRRLRSLTAQIVILDVNDHNPTFISFP-NAHVKEDVTV--GSLVHHITAHDP 1191 Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239 D G N + Y+I+ GN M F +D SG ++ LDYE + L + A D G+P+ S+ Sbjct: 1192 DEGRNGKVTYSILSGNENMTFMLDESSGLLTTTCPLDYEMKTQHILTVLALDDGTPALSS 1251 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 + L + + DVND AP F L++ SV EN G + RV+A D D GVN++L + + Sbjct: 1252 SQTLTVTVLDVNDEAPVFKQHLYEASVKENQNPGEFVTRVEALDRDSGVNSKLQFEIMP- 1310 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 + +L I+ +G V T+ LDRE Q + L V DGG P S+T T Sbjct: 1311 --GASFEL-FEINSDTGEVVTTTILDREIQEVFTLRVLVRDGGFPSLSSTTTILCTVEDE 1367 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQ 417 F+ Y++E+ E++ P V T+ A+D D N + Y I GNT F+I Sbjct: 1368 NDHAPEFIVSSYDIEVLENQEPEV-VYTVLASDMDAGNNRAVEYHIIDGNTDECFTINEM 1426 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYT 475 +G ++ + LD +Q + L + +D G RS +Q+ + DAN+++P F Y Sbjct: 1427 SGE--LSTTRALDREQISNFTLVILCSDLGDPPRSSVIHLQVRVLDANDHSPSFPTLYYQ 1484 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 +SV EDA +GT VLV+SA D D G+N Q Y L+ E S F I+P +G + T Sbjct: 1485 SSVREDAEVGTVVLVLSAVDKDEGLNGQTEYFLTDEASG--------AFTIDPMSGTLKT 1536 Query: 536 NKLLDRETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 + LDRE S + + ARD + S S T +++ V DVNDN+PV +Q + + ++ Sbjct: 1537 SNTLDREARSQHTFSAVARDCSIQGSRSTTVIIKVYVTDVNDNDPVLEQNPFDVFLSPES 1596 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654 + V A D D+G NG + + + F ID +G I+ + E Sbjct: 1597 PTNQTTVIVRADDLDLGPNGTVVFSF---AETQSMFSIDKYTGEIQFQQNPSSEYFPIW- 1652 Query: 655 LKAVAIDGGTPPQSST--VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 L+ D G P +++T +++H++ ED+ S F ++EN GT+I ++A Sbjct: 1653 LQLKVTDQGIPARTTTGLLVIHMEGEDVKIS---FSHHLYKGLVTENCEAGTSIVTVKAF 1709 Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP 772 PD ++ + YSI G++ SL ++ G + +D + R + +L++ A S Sbjct: 1710 APDSIQDS-MKYSIFSGNEDGVLSLCSKSGQLTVKEPKFLDFEV---RNEVQLIVLAESS 1765 Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYR 830 +V +L+ D NDN+P + + + +V A D D + ++Y Sbjct: 1766 GHRAYCKVAVLIQDENDNSPCFEQSIYQASVSESQLYNAHVIQVFATDLDSGLNGLIEYS 1825 Query: 831 ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 ILSGN ++ +G +T L+ + ++ V TD Sbjct: 1826 ILSGNQEEAFQIDALSGVITTKAILDYELTSSYSLIVQATD 1866 Score = 333 bits (819), Expect = 3e-89 Identities = 264/884 (29%), Positives = 423/884 (47%), Gaps = 68/884 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND +PVF+ YEASV+E + G V ++A D+D G N+++++ E++ + Sbjct: 1257 VTVLDVNDEAPVFKQHLYEASVKENQNPGEFVTRVEALDRDSGVNSKLQF--EIMPGASF 1314 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 ++F I+ +G ++T LDRE +T+ V D P L Sbjct: 1315 -----------------ELFEINSDTGEVVTTTILDREIQEVFTLRVLVRDGGFP---SL 1354 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SST TI + D+ND+ P+F +Y + V E+ + V+ + A+D D G N A+ Y Sbjct: 1355 SSTTTILCTVEDENDHAPEFIVSSYDIEVLEN---QEPEVVYTVLASDMDAGNNRAVEYH 1411 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 II GNT F+I+ +SG++S + LD EQ+ ++ LVI D G P RS+ L + + D Sbjct: 1412 IIDGNTDECFTINEMSGELSTTRALDREQISNFTLVILCSDLGDPPRSSVIHLQVRVLDA 1471 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 ND++P F T +Q SV E+ +G ++ + A D DEG+N + Y +TD + +G T Sbjct: 1472 NDHSPSFPTLYYQSSVREDAEVGTVVLVLSAVDKDEGLNGQTEYFLTD-EASG----AFT 1526 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPPRSATATXXXXXXXXXXXXXXFMPG 369 IDP SG + TS LDRE ++++ A D RS T Sbjct: 1527 IDPMSGTLKTSNTLDREARSQHTFSAVARDCSIQGSRSTTVIIKVYVTDVNDNDPVLEQN 1586 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 ++V L+ + P V + A D D + T+ FSI G Q Sbjct: 1587 PFDVFLSPESPTNQTTVIVRADDLDLGPNGTVVFSFAETQSMFSIDKYTGE---IQFQQN 1643 Query: 430 DFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 + L + TD G R+ T ++ I++ + + F + Y V E+ GT+ Sbjct: 1644 PSSEYFPIWLQLKVTDQGIPARTTTGLLVIHM-EGEDVKISFSHHLYKGLVTENCEAGTS 1702 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN--KLLDRETMS 545 ++ V A D I + YS+ S NE D + ++G +T K LD E + Sbjct: 1703 IVTVKAFAPD-SIQDSMKYSIFS--GNE-----DGVLSLCSKSGQLTVKEPKFLDFEVRN 1754 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 L V A G + V + + D NDN P F+Q +Y A++ E L V QV A Sbjct: 1755 EVQLIVLAESSGHRAY---CKVAVLIQDENDNSPCFEQSIYQASVSESQLYNAHVIQVFA 1811 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 TD D GLNG I Y + ++EE +F ID SGVI T LD E +++ L A D G P Sbjct: 1812 TDLDSGLNGLIEYSILSGNQEE-AFQIDALSGVITTKAILDYELTSSYSLIVQATDKGMP 1870 Query: 666 PQSSTVIVHIKIEDINDSPPVF-ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 S+T ++ +++ DIND+ P F S+ + I+E+S G + + HD D +A + Sbjct: 1871 RLSNTTVIKVQVTDINDNAPAFLPSEAVE--ITEDSLPGVIVTHVSVHDVDLN-SAFIFS 1927 Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILV 784 K + F+++ G +V + LD+E +YEL+I+ + + + + + V Sbjct: 1928 FAKESNPGTKFAIDQNTG----VVVLVKTLDFEE-MTEYELLIQISDSVHYTEGALVVRV 1982 Query: 785 TDVNDNAPVM-KDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLILL 842 DVNDN PV +DF + + PVG + A D + + + YRILS + + Sbjct: 1983 LDVNDNPPVFSQDFYQV--TVPESIPVGYSVLTLSATDLESNENISYRILSSSKE--FSI 2038 Query: 843 NETTGSM-TLSPQLNTNVPKLATMEVSVTDGVN-EIKAMMQLSV 884 + G++ T+SP L + V +DG N +++A+ + + Sbjct: 2039 DPKNGTIFTISPVLLLDTISTTQFLVEASDGGNPDLRALTLVEI 2082 Score = 306 bits (751), Expect = 6e-81 Identities = 270/886 (30%), Positives = 405/886 (45%), Gaps = 79/886 (8%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 IH Q+ VLD NDHSP F Y++SVRE A GT VL L A D+D G N + EY + Sbjct: 1462 IHLQVRVLDANDHSPSFPTLYYQSSVREDAEVGTVVLVLSAVDKDEGLNGQTEYFLT--- 1518 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 ++A F ID SG L T +LDRE +++T A D + + Sbjct: 1519 ------DEASGA-----------FTIDPMSGTLKTSNTLDREARSQHTFSAVARDCS--I 1559 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 S+T I V + D NDN P + + V + + VI ++A D D+G N Sbjct: 1560 QGSRSTTVIIKVYVTDVNDNDPVLEQNPFDVFLSPESPTNQTTVI--VRADDLDLGPNGT 1617 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 + ++ TQ FSID +G++ + E + L ++ D G P+R+ T L+I+ Sbjct: 1618 VVFSF--AETQSMFSIDKYTGEIQFQQNPSSEYFPIW-LQLKVTDQGIPARTTTGLLVIH 1674 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + D F L++ V+EN G SIV V+A+ A + + + Y++ ++GN D Sbjct: 1675 MEG-EDVKISFSHHLYKGLVTENCEAGTSIVTVKAF-APDSIQDSMKYSI----FSGNED 1728 Query: 307 LPITIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 +++ +SG + LD E + + QL+V A G A Sbjct: 1729 GVLSLCSKSGQLTVKEPKFLDFEVRNEVQLIVLAESSG---HRAYCKVAVLIQDENDNSP 1785 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGL 422 F Y+ ++E + V+ + ATD D + + Y I GN F I + +G + Sbjct: 1786 CFEQSIYQASVSESQLYNAHVIQVFATDLDSGLNGLIEYSILSGNQEEAFQIDALSG--V 1843 Query: 423 ITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 IT LD++ Y L V ATD G S+T ++++ +TD N+ AP F + + E Sbjct: 1844 ITTKAILDYELTSSYSLIVQATDKGMPRLSNTTVIKVQVTDINDNAPAFLPSE-AVEITE 1902 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 D+ G V VS D D +N+ +S + E SN +F I+ TG + K LD Sbjct: 1903 DSLPGVIVTHVSVHDVD--LNSAFIFSFAKE-SNPGT-----KFAIDQNTGVVVLVKTLD 1954 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTD-VEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 E M+ Y L + D S+ T + + V+DVNDN PVF Q Y + E VG S Sbjct: 1955 FEEMTEYELLIQISD----SVHYTEGALVVRVLDVNDNPPVFSQDFYQVTVPESIPVGYS 2010 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT-NKALDRESVATHDLKAV 658 V + ATD + N I Y + +E F IDP +G I T + L ++++T Sbjct: 2011 VLTLSATDLES--NENISYRILSSSKE---FSIDPKNGTIFTISPVLLLDTISTTQFLVE 2065 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-EG 717 A DGG P + +V I IED+N+ P F +SE++ +G+T+ D D Sbjct: 2066 ASDGGNPDLRALTLVEIGIEDMNNYAPEFTVKSYNLSLSEDALVGSTLVTFSNIDHDWTR 2125 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDK------AELVTMVDLDYESPRKKYELVIRAAS 771 N V YSI G+ N+F +ET+ + LV + LD E+ +ELVI A+ Sbjct: 2126 ENTYVEYSIISGNSQNNFHVETKFFHSEYPYKQVGYLVLLHSLDREASAS-HELVILASD 2184 Query: 772 ---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADVTDKL 827 PPL + + I V DVNDN P + K+ P+G V A D D Sbjct: 2185 SGCPPLSSTAVISIQVLDVNDNPPNFSSLSY-HTHVKESTPLGSHITVVSANDRDTGSHA 2243 Query: 828 Q--YRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + Y I+SGN L E TG + L L+ T+ V +D Sbjct: 2244 EIIYNIISGNEKGHFYLEENTGVLYLIKPLDYEKMTKFTLTVQASD 2289 Score = 304 bits (746), Expect = 2e-80 Identities = 246/804 (30%), Positives = 376/804 (46%), Gaps = 65/804 (8%) Query: 11 INVLDCNDHSPVFEM----QQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 ++V D ND+ P F ++ V EG V T+ A D D G NAEV Y++ Sbjct: 827 VSVTDINDNRPFFPQCLPGKELHVKVLEGQPVNMLVTTVFAKDPDEGNNAEVTYSV---- 882 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 + ED+ D F+ID +G + T L + Y + V ATDQ P Sbjct: 883 ----SSEDSS-----------DHFKIDANNGEIRTTTILSYDYRPSYRMSVIATDQGVP- 926 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD-ADVGANS 185 L A +++ +I + S+ + + E++ T +++ IK++D N Sbjct: 927 --PLQGQAVVNIQVIPLSKGRAIMSQNIRHLIIPENLKPT--KIMSLIKSSDHLQQHYNG 982 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRL-VIRAQDGGSPSRSNTTQLL 244 + ++I+ + F IDS +GD+ L K LDYE Y VI + S S+T L Sbjct: 983 KLHFSIVADDKDGHFEIDSSTGDLFLSKELDYETTSHYLFRVITTDHSKNLSLSSTVFLS 1042 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG-VNAELTYTMTDKDYTG 303 I++ D ND++P F L SV ENVPIG + A D D +N+ + Y + + Sbjct: 1043 IDVEDQNDHSPSFQDELIVISVEENVPIGTLVYVFNAKDDDGSFLNSRIQYYIESHNPGT 1102 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-----DPPRSATATXXXXXXX 358 N P I P G + T +LDRE+ L VTA+D RS TA Sbjct: 1103 N---PFLIHPSFGTLVTVSRLDRESIPTVILTVTASDQAVNVTDRRLRSLTAQIVILDVN 1159 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITS 416 P + + ED G+ V +TA D DE + ++ Y I GN F + Sbjct: 1160 DHNPTFISFPNAH---VKEDVTVGSLVHHITAHDPDEGRNGKVTYSILSGNENMTFMLDE 1216 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPY 474 + GL+T PLD++ + +++LTV A D G S + + + + D N+ APVF+ Y Sbjct: 1217 SS--GLLTTTCPLDYEMKTQHILTVLALDDGTPALSSSQTLTVTVLDVNDEAPVFKQHLY 1274 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 ASV E+ G V V A D D G+N+++ + + S E F IN TG + Sbjct: 1275 EASVKENQNPGEFVTRVEALDRDSGVNSKLQFEIMPGASFEL-------FEINSDTGEVV 1327 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 T +LDRE + L V RDGG PSLS TT + +V D ND+ P F Y ++E+ Sbjct: 1328 TTTILDREIQEVFTLRVLVRDGGFPSLSSTTTILCTVEDENDHAPEFIVSSYDIEVLENQ 1387 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654 V V A+D D G N + Y + + +E F I+ SG + T +ALDRE ++ Sbjct: 1388 -EPEVVYTVLASDMDAGNNRAVEYHIIDGNTDE-CFTINEMSGELSTTRALDREQISNFT 1445 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 L + D G PP+SS + + +++ D ND P F + + E++ +GT + + A D Sbjct: 1446 LVILCSDLGDPPRSSVIHLQVRVLDANDHSPSFPTLYYQSSVREDAEVGTVVLVLSAVDK 1505 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES-PRKKYELVIRAAS-- 771 DEG N Y + + S +F+++ G+ L T LD E+ + + V R S Sbjct: 1506 DEGLNGQTEYFLT-DEASGAFTIDPMSGT----LKTSNTLDREARSQHTFSAVARDCSIQ 1560 Query: 772 PPLWNDVRVEILVTDVNDNAPVMK 795 V +++ VTDVNDN PV++ Sbjct: 1561 GSRSTTVIIKVYVTDVNDNDPVLE 1584 Score = 302 bits (742), Expect = 7e-80 Identities = 230/753 (30%), Positives = 362/753 (48%), Gaps = 72/753 (9%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72 + D ND+SP FE Y+ASV E V+ + ATD D G N +EY+I + N Sbjct: 1777 IQDENDNSPCFEQSIYQASVSESQLYNAHVIQVFATDLDSGLNGLIEYSIL-----SGNQ 1831 Query: 73 EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132 E+A F+ID SG + T+A LD E + Y+++V+ATD+ P RLS+ Sbjct: 1832 EEA--------------FQIDALSGVITTKAILDYELTSSYSLIVQATDKGMP---RLSN 1874 Query: 133 TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192 T I V + D NDN P F + V + ED ++ + D D+ NSA ++ Sbjct: 1875 TTVIKVQVTDINDNAPAFL-PSEAVEITED--SLPGVIVTHVSVHDVDL--NSAFIFSFA 1929 Query: 193 -GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251 N +F+ID +G V LVKTLD+E++ Y L+I+ D + L++ + DVN Sbjct: 1930 KESNPGTKFAIDQNTGVVVLVKTLDFEEMTEYELLIQISDSVHYTEG---ALVVRVLDVN 1986 Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311 DN P F +Q +V E++P+GYS++ + A D + N + K++ +I Sbjct: 1987 DNPPVFSQDFYQVTVPESIPVGYSVLTLSATDLESNENISYRILSSSKEF--------SI 2038 Query: 312 DPRSGWVYT-SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 DP++G ++T S L +T + Q LV A+DGG+P A F Sbjct: 2039 DPKNGTIFTISPVLLLDTISTTQFLVEASDGGNPDLRALTLVEIGIEDMNNYAPEFTVKS 2098 Query: 371 YEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQ--------NG 419 Y + L+ED G+ +VT + D D E+ + Y I GN++ F + ++ Sbjct: 2099 YNLSLSEDALVGSTLVTFSNIDHDWTRENTYVEYSIISGNSQNNFHVETKFFHSEYPYKQ 2158 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477 G + + LD + + L + A+DSG S TA++ I + D N+ P F + Y Sbjct: 2159 VGYLVLLHSLDREASASHELVILASDSGCPPLSSTAVISIQVLDVNDNPPNFSSLSYHTH 2218 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 V E P+G+ + VVSA D D G +A+I Y++ IS H F + TG + K Sbjct: 2219 VKESTPLGSHITVVSANDRDTGSHAEIIYNI---ISGNEKGH----FYLEENTGVLYLIK 2271 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LD E M+ + LTV A D S V +SV+D ND+ P F ++ + E+ + Sbjct: 2272 PLDYEKMTKFTLTVQASDAEKKHFSFAV-VFVSVLDDNDHAPQFMFSSFSCIVPENLPIS 2330 Query: 598 TSVSQVGATDADVGLNGRIHYEL-DP------KDREEGSFVIDPASGVIRTNKALDRESV 650 +++ + A D D G G + Y + P + F+IDP +G I + LD E+ Sbjct: 2331 STICSINALDFDAGPYGELTYSIVSPCFLTHGMSYDHDLFLIDPLTGDIHAKQILDYENG 2390 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710 + L A D G +++++V + IE I++ P+F D F + E + IG + Sbjct: 2391 NKYCLTVQAKDKG--DATASLVVWVDIEGIDEFEPIFTQDQYFFTLPEKNKDRQLIGRVE 2448 Query: 711 AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 A D D G + V+ YS+ G S FS+ G+ Sbjct: 2449 ASDADAGIDGVILYSL--GTSSPFFSVNKTNGN 2479 Score = 288 bits (706), Expect = 2e-75 Identities = 227/755 (30%), Positives = 344/755 (45%), Gaps = 45/755 (5%) Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195 + V I D+NDN P F + Y SV E S N + ++ ATD D G N I Y+I+ GN Sbjct: 1773 VAVLIQDENDNSPCFEQSIYQASVSE--SQLYNAHVIQVFATDLDSGLNGLIEYSILSGN 1830 Query: 196 TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP 255 + F ID+LSG ++ LDYE SY L+++A D G P SNTT + + + D+NDNAP Sbjct: 1831 QEEAFQIDALSGVITTKAILDYELTSSYSLIVQATDKGMPRLSNTTVIKVQVTDINDNAP 1890 Query: 256 RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315 F S E +++P G + V +D D +N+ ++ + G ID + Sbjct: 1891 AFLPSEAVEITEDSLP-GVIVTHVSVHDVD--LNSAFIFSFAKESNPGT---KFAIDQNT 1944 Query: 316 GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375 G V LD E +Y+LL+ +D A F Y+V + Sbjct: 1945 GVVVLVKTLDFEEMTEYELLIQISDSVHYTEGALVVRVLDVNDNPPV---FSQDFYQVTV 2001 Query: 376 AEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435 E P G V+TL+ATD + + + Y I + FSI +NG + T++ L Sbjct: 2002 PESIPVGYSVLTLSATDLESNENISYRILSSSKE--FSIDPKNGT-IFTISPVLLLDTIS 2058 Query: 436 RYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 V A+D G A+ V+I I D NNYAP F Y S+ EDA +G+T++ S Sbjct: 2059 TTQFLVEASDGGNPDLRALTLVEIGIEDMNNYAPEFTVKSYNLSLSEDALVGSTLVTFSN 2118 Query: 494 TDSD-VGINAQITYSLSSEISNEAVAHHDQQFVINP----QTGAITTNKLLDRETMSGYL 548 D D N + YS+ S S H + +F + Q G + LDRE + + Sbjct: 2119 IDHDWTRENTYVEYSIISGNSQNNF-HVETKFFHSEYPYKQVGYLVLLHSLDREASASHE 2177 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 L + A D G P LS T + I V+DVNDN P F Y ++ E +G+ ++ V A D Sbjct: 2178 LVILASDSGCPPLSSTAVISIQVLDVNDNPPNFSSLSYHTHVKESTPLGSHITVVSANDR 2237 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 D G + I Y + E+G F ++ +GV+ K LD E + L A D Sbjct: 2238 DTGSHAEIIYNI-ISGNEKGHFYLEENTGVLYLIKPLDYEKMTKFTLTVQASD-AEKKHF 2295 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 S +V + + D ND P F + + EN PI +TI I A D D GP + YSI Sbjct: 2296 SFAVVFVSVLDDNDHAPQFMFSSFSCIVPENLPISSTICSINALDFDAGPYGELTYSIVS 2355 Query: 729 --------GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP-PLWNDVR 779 D + F ++ G A+ + LDYE+ KY L ++A + Sbjct: 2356 PCFLTHGMSYDHDLFLIDPLTGDIHAKQI----LDYEN-GNKYCLTVQAKDKGDATASLV 2410 Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNA 837 V + + +++ P+ Q F + GRV A DAD + + Y + G ++ Sbjct: 2411 VWVDIEGIDEFEPIFTQDQYFFTLPEKNKDRQLIGRVEASDADAGIDGVILYSL--GTSS 2468 Query: 838 NLILLNETTGSMTL---SPQLNTNVPKLATMEVSV 869 +N+T G++ L P + + + K T+E+ + Sbjct: 2469 PFFSVNKTNGNIYLIRALPLIKSQLNKEDTLEMKI 2503 Score = 258 bits (633), Expect = 1e-66 Identities = 229/822 (27%), Positives = 367/822 (44%), Gaps = 65/822 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEY---------- 60 + V D ND+SP F V E + + A D D GKN ++ Y Sbjct: 680 VRVWDENDNSPTFLHDVLFLKVEESPVPQGVIGKITAIDMDSGKNGQLLYFLLSDGKFFK 739 Query: 61 ---------TIELVT----ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDR 107 TI ++T A + D V + G L+ +LDR Sbjct: 740 MNPNTGPAGTIYVITWADGAAAFSGTDFAFSSDELQAFVLKSLFCELGEGELINWVALDR 799 Query: 108 EKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSE----KTYTVSVDEDI 163 E + + V TD+ SP + +T ++V++ D NDN P F + K V V E Sbjct: 800 EHRGHHEMTVLVTDRGSPPRN---ATMAVYVSVTDINDNRPFFPQCLPGKELHVKVLEGQ 856 Query: 164 SVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY 223 V N ++ + A D D G N+ + Y++ ++ F ID+ +G++ L Y+ SY Sbjct: 857 PV--NMLVTTVFAKDPDEGNNAEVTYSVSSEDSSDHFKIDANNGEIRTTTILSYDYRPSY 914 Query: 224 RLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYD 283 R+ + A D G P + I + ++ ++ + EN+ + +++ D Sbjct: 915 RMSVIATDQGVPPLQGQAVVNIQVIPLSKGRAIMSQNIRHLIIPENLKPTKIMSLIKSSD 974 Query: 284 -ADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD-G 341 + N +L +++ D G+ + ID +G ++ S +LD ET + Y V TD Sbjct: 975 HLQQHYNGKLHFSIVADDKDGHFE----IDSSTGDLFLSKELDYETTSHYLFRVITTDHS 1030 Query: 342 GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE---DNR 398 + S+T F + + E+ P GT V A D D ++R Sbjct: 1031 KNLSLSSTVFLSIDVEDQNDHSPSFQDELIVISVEENVPIGTLVYVFNAKDDDGSFLNSR 1090 Query: 399 LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD-----SGGRSDTA 453 + Y I N + + L+TV++ LD + +LTV+A+D + R + Sbjct: 1091 IQYYIESHNPGTNPFLIHPSFGTLVTVSR-LDRESIPTVILTVTASDQAVNVTDRRLRSL 1149 Query: 454 MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513 QI I D N++ P F + P A V ED +G+ V ++A D D G N ++TYS+ S Sbjct: 1150 TAQIVILDVNDHNPTFISFP-NAHVKEDVTVGSLVHHITAHDPDEGRNGKVTYSILS--G 1206 Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 NE + F+++ +G +TT LD E + ++LTV A D G P+LS + + ++V+D Sbjct: 1207 NE-----NMTFMLDESSGLLTTTCPLDYEMKTQHILTVLALDDGTPALSSSQTLTVTVLD 1261 Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633 VND PVFKQ LY A++ E+ G V++V A D D G+N ++ +E+ P E F I+ Sbjct: 1262 VNDEAPVFKQHLYEASVKENQNPGEFVTRVEALDRDSGVNSKLQFEIMPGASFE-LFEIN 1320 Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693 +G + T LDRE L+ + DGG P SST + +ED ND P F Sbjct: 1321 SDTGEVVTTTILDREIQEVFTLRVLVRDGGFPSLSSTTTILCTVEDENDHAPEFIVSSYD 1380 Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753 + EN + + A D D G N V Y I G+ F++ G EL T Sbjct: 1381 IEVLENQE-PEVVYTVLASDMDAGNNRAVEYHIIDGNTDECFTINEMSG----ELSTTRA 1435 Query: 754 LDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAP 792 LD E + LVI + PP + + +++ V D ND++P Sbjct: 1436 LDREQ-ISNFTLVILCSDLGDPPRSSVIHLQVRVLDANDHSP 1476 Score = 208 bits (507), Expect = 2e-51 Identities = 172/568 (30%), Positives = 259/568 (45%), Gaps = 34/568 (5%) Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF---MPG-QYEVELAEDE 379 LDRE + +++ V TD G PPR+AT F +PG + V++ E + Sbjct: 797 LDREHRGHHEMTVLVTDRGSPPRNATMAVYVSVTDINDNRPFFPQCLPGKELHVKVLEGQ 856 Query: 380 PPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437 P V T+ A D DE N Y ++ ++ F I + NG T D++ Y Sbjct: 857 PVNMLVTTVFAKDPDEGNNAEVTYSVSSEDSSDHFKIDANNGEIRTTTILSYDYRPS--Y 914 Query: 438 VLTVSATDSG--GRSDTAMVQINITD-ANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494 ++V ATD G A+V I + + A + +N + P L+ S+ Sbjct: 915 RMSVIATDQGVPPLQGQAVVNIQVIPLSKGRAIMSQNIRHLIIPENLKPTKIMSLIKSSD 974 Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554 N ++ +S+ ++ D F I+ TG + +K LD ET S YL V Sbjct: 975 HLQQHYNGKLHFSIVAD-------DKDGHFEIDSSTGDLFLSKELDYETTSHYLFRVITT 1027 Query: 555 DGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG-L 612 D SLS T + I V D ND+ P F+ +L ++ E+ +GT V A D D L Sbjct: 1028 DHSKNLSLSSTVFLSIDVEDQNDHSPSFQDELIVISVEENVPIGTLVYVFNAKDDDGSFL 1087 Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG---TPPQSS 669 N RI Y ++ + F+I P+ G + T LDRES+ T L A D T + Sbjct: 1088 NSRIQYYIESHNPGTNPFLIHPSFGTLVTVSRLDRESIPTVILTVTASDQAVNVTDRRLR 1147 Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729 ++ I I D+ND P F S ++ E+ +G+ + I AHDPDEG N V YSI G Sbjct: 1148 SLTAQIVILDVNDHNPTFIS-FPNAHVKEDVTVGSLVHHITAHDPDEGRNGKVTYSILSG 1206 Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA--ASPPLWNDVRVEILVTDV 787 +++ +F L+ G L T LDYE + V+ +P L + + + V DV Sbjct: 1207 NENMTFMLDESSGL----LTTTCPLDYEMKTQHILTVLALDDGTPALSSSQTLTVTVLDV 1262 Query: 788 NDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDAD--VTDKLQYRILSGNNANLILLNE 844 ND APV K + + K+ G F RV A D D V KLQ+ I+ G + L +N Sbjct: 1263 NDEAPVFKQ-HLYEASVKENQNPGEFVTRVEALDRDSGVNSKLQFEIMPGASFELFEINS 1321 Query: 845 TTGSMTLSPQLNTNVPKLATMEVSVTDG 872 TG + + L+ + ++ T+ V V DG Sbjct: 1322 DTGEVVTTTILDREIQEVFTLRVLVRDG 1349 Score = 166 bits (403), Expect = 9e-39 Identities = 138/478 (28%), Positives = 219/478 (45%), Gaps = 35/478 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTAD 68 +I + D N+++P F ++ Y S+ E A G+T++T D D +N VEY+I ++ + Sbjct: 2081 EIGIEDMNNYAPEFTVKSYNLSLSEDALVGSTLVTFSNIDHDWTRENTYVEYSI--ISGN 2138 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 + N + V G L+ SLDRE A + +++ A+D P Sbjct: 2139 SQNNFHVETKFFHSEYPYKQV-------GYLVLLHSLDREASASHELVILASDSGCP--- 2188 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 LSSTA I + ++D NDN P FS +Y V E + + I + A D D G+++ I Sbjct: 2189 PLSSTAVISIQVLDVNDNPPNFSSLSYHTHVKESTPLGSH--ITVVSANDRDTGSHAEII 2246 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y II GN + F ++ +G + L+K LDYE++ + L ++A D + + +++ Sbjct: 2247 YNIISGNEKGHFYLEENTGVLYLIKPLDYEKMTKFTLTVQASD-AEKKHFSFAVVFVSVL 2305 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY-----TG 303 D ND+AP+F S F V EN+PI +I + A D D G ELTY++ + + Sbjct: 2306 DDNDHAPQFMFSSFSCIVPENLPISSTICSINALDFDAGPYGELTYSIVSPCFLTHGMSY 2365 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 + DL IDP +G ++ LD E KY L V A D GD +A+ Sbjct: 2366 DHDL-FLIDPLTGDIHAKQILDYENGNKYCLTVQAKDKGD--ATASLVVWVDIEGIDEFE 2422 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRG 421 F QY L E + + A+DAD D + Y + G + FS+ NG Sbjct: 2423 PIFTQDQYFFTLPEKNKDRQLIGRVEASDADAGIDGVILYSL--GTSSPFFSVNKTNGNI 2480 Query: 422 LITVAQPLDFKQ-------ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENA 472 + A PL Q E + + +DS S T V ++ + VF ++ Sbjct: 2481 YLIRALPLIKSQLNKEDTLEMKIIAHSPKSDSKFASCTVFVNVSFSSEGTPLAVFASS 2538 Score = 134 bits (324), Expect = 3e-29 Identities = 131/439 (29%), Positives = 191/439 (43%), Gaps = 28/439 (6%) Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT--AMVQINITDANNYAPVFENAPYTA 476 G G+I + PL + L VSA D GG + A V I+I FE YT Sbjct: 325 GEGIIYLTLPLSHLESTTLSLMVSAQDGGGLTAVINADVTIHIFQTTLAPAEFERPKYTF 384 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 V+ED P + + V A + + + I Y +SS +F I+P+ G I T Sbjct: 385 LVYEDVPEDSPIGTVKAREP-LNSSEPIFYRISS-------GDLGGKFSIHPRLGTIRTR 436 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 K LD ET +LTV A+ G P+ S +T+V I+V+DVNDN P F + I + Sbjct: 437 KPLDHETQPVVVLTVQAQLGSAPACS-STEVNITVMDVNDNHPAFLRTSDEIRISQTTPP 495 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 GT++ A D D G NG I Y + + G F ID A GV+ N +L L Sbjct: 496 GTALYLARAEDRDSGRNGLIRYSI--ASPQPGVFAIDRALGVLFLNGSLGAGEQRELTLT 553 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPP-VFESDCLTFYISENSPIGTTIGEIRAHD-P 714 A D G PQ++ +++ + IE SP FE +SE+ T + + +AH Sbjct: 554 LRAEDQGVHPQAALLVLTVVIEKREHSPSWTFEHLVYQVEVSESLSPMTQMLQTQAHPLG 613 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP- 773 + + + YS++ DS F + G + DYES + Y + A P Sbjct: 614 PQRAASPLRYSLEPSVDSAMFGIRPYTG----WIYLRRQFDYES-TQTYNFRVFAWIPED 668 Query: 774 --LWN-DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQ 828 L N V + V D NDN+P + + P G G++ A D D +L Sbjct: 669 GFLQNVSTTVIVRVWDENDNSPTFLHDVLFLKVEESPVPQGVIGKITAIDMDSGKNGQLL 728 Query: 829 YRILSGNNANLILLNETTG 847 Y +LS + +N TG Sbjct: 729 YFLLS--DGKFFKMNPNTG 745 Score = 98.3 bits (234), Expect = 3e-18 Identities = 111/447 (24%), Positives = 189/447 (42%), Gaps = 24/447 (5%) Query: 73 EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132 E A V ++ +I G G + L + +++V A D ++ +++ Sbjct: 304 EAASADGEAAARYVANLAKILGE-GIIYLTLPLSHLESTTLSLMVSAQDGGG-LTAVINA 361 Query: 133 TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192 TIH I +F YT V ED+ D+P I +KA + + ++ I Y I Sbjct: 362 DVTIH--IFQTTLAPAEFERPKYTFLVYEDVP-EDSP-IGTVKAREP-LNSSEPIFYRIS 416 Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252 G+ +FSI G + K LD+E L ++AQ G +P+ S+T ++ I + DVND Sbjct: 417 SGDLGGKFSIHPRLGTIRTRKPLDHETQPVVVLTVQAQLGSAPACSST-EVNITVMDVND 475 Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312 N P F + + +S+ P G ++ +A D D G N + Y++ G ID Sbjct: 476 NHPAFLRTSDEIRISQTTPPGTALYLARAEDRDSGRNGLIRYSIASPQ-PG----VFAID 530 Query: 313 PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX-XXXFMPGQY 371 G ++ +G L Q + L + A D G P++A F Y Sbjct: 531 RALGVLFLNGSLGAGEQRELTLTLRAEDQGVHPQAALLVLTVVIEKREHSPSWTFEHLVY 590 Query: 372 EVELAEDEPPGTPVVTLTATDADED---NRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 +VE++E P T ++ A + L Y + F I G I + + Sbjct: 591 QVEVSESLSPMTQMLQTQAHPLGPQRAASPLRYSLEPSVDSAMFGIRPYT--GWIYLRRQ 648 Query: 429 LDFKQERRYVLTVSA---TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 D++ + Y V A D ++ + V + + D N+ +P F + V E++P+ Sbjct: 649 FDYESTQTYNFRVFAWIPEDGFLQNVSTTVIVRVWDENDNSPTFLHDVLFLKV-EESPVP 707 Query: 486 TTVL-VVSATDSDVGINAQITYSLSSE 511 V+ ++A D D G N Q+ Y L S+ Sbjct: 708 QGVIGKITAIDMDSGKNGQLLYFLLSD 734 Score = 90.2 bits (214), Expect = 7e-16 Identities = 62/236 (26%), Positives = 101/236 (42%), Gaps = 11/236 (4%) Query: 644 ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT-----FYISE 698 ALDRE H++ + D G+PP+++T+ V++ + DIND+ P F CL + E Sbjct: 796 ALDREHRGHHEMTVLVTDRGSPPRNATMAVYVSVTDINDNRPFF-PQCLPGKELHVKVLE 854 Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758 P+ + + A DPDEG NA V YS+ D S+ F ++ G + T++ DY Sbjct: 855 GQPVNMLVTTVFAKDPDEGNNAEVTYSVSSEDSSDHFKIDANNG--EIRTTTILSYDYRP 912 Query: 759 PRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKD---FQIIFNNYKDCFPVGPFGR 815 + + PPL V I V ++ +M II N K + Sbjct: 913 SYRMSVIATDQGVPPLQGQAVVNIQVIPLSKGRAIMSQNIRHLIIPENLKPTKIMSLIKS 972 Query: 816 VPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 KL + I++ + ++ +TG + LS +L+ V TD Sbjct: 973 SDHLQQHYNGKLHFSIVADDKDGHFEIDSSTGDLFLSKELDYETTSHYLFRVITTD 1028 Score = 80.2 bits (189), Expect = 8e-13 Identities = 82/305 (26%), Positives = 131/305 (42%), Gaps = 44/305 (14%) Query: 2 SVPFCIHQQIN--VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVE 59 S P C ++N V+D ND+ P F E + + GT + +A D+D G+N + Sbjct: 457 SAPACSSTEVNITVMDVNDNHPAFLRTSDEIRISQTTPPGTALYLARAEDRDSGRNGLIR 516 Query: 60 YTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKA 119 Y+I +P+ VF ID G L SL + T+ ++A Sbjct: 517 YSI-------ASPQPG-------------VFAIDRALGVLFLNGSLGAGEQRELTLTLRA 556 Query: 120 TDQ-ASPVSDRLSSTATIHVNIIDDNDNYPQ--FSEKTYTVSVDEDISVTDNPVIAKIKA 176 DQ P + L T +I+ ++ P F Y V V E +S P+ ++ Sbjct: 557 EDQGVHPQAALLVLTV-----VIEKREHSPSWTFEHLVYQVEVSESLS----PMTQMLQT 607 Query: 177 TDADVG---ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA---Q 230 +G A S +RY++ F I +G + L + DYE ++Y + A + Sbjct: 608 QAHPLGPQRAASPLRYSLEPSVDSAMFGIRPYTGWIYLRRQFDYESTQTYNFRVFAWIPE 667 Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRF-YTSLFQESVSENVPIGYSIVRVQAYDADEGVN 289 DG + S T +++ + D NDN+P F + LF + VP G I ++ A D D G N Sbjct: 668 DGFLQNVSTT--VIVRVWDENDNSPTFLHDVLFLKVEESPVPQGV-IGKITAIDMDSGKN 724 Query: 290 AELTY 294 +L Y Sbjct: 725 GQLLY 729 Score = 74.5 bits (175), Expect = 4e-11 Identities = 57/160 (35%), Positives = 78/160 (48%), Gaps = 17/160 (10%) Query: 491 VSATDSDVGINAQITYSL-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET-MSGYL 548 V+A+D+D G+ I YSL +S EA Q F I+P G I ++ +DRE + Y Sbjct: 79 VTASDADSGLYGFIEYSLYDGFLSYEA----PQAFRIDPHDGQICVSQDIDRERDPATYD 134 Query: 549 LTVTARDGGVP----------SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 L V A+DG LS V + + DVNDN PVF Y +I ++ GT Sbjct: 135 LLVEAKDGDEQRMTHLALVKGGLSAQAFVRVDLEDVNDNHPVFNPSTYVTSISDETQPGT 194 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638 + V ATD D G+ G + YEL P F ID +G+ Sbjct: 195 EIINVLATDQDSGIYGTVAYELIP-GNVSSLFTIDSTTGL 233 Score = 69.3 bits (162), Expect = 1e-09 Identities = 56/169 (33%), Positives = 84/169 (49%), Gaps = 16/169 (9%) Query: 601 SQVGATDADVGLNGRIHYEL-DPKDREEG--SFVIDPASGVIRTNKALDRE-SVATHDLK 656 ++V A+DAD GL G I Y L D E +F IDP G I ++ +DRE AT+DL Sbjct: 77 TEVTASDADSGLYGFIEYSLYDGFLSYEAPQAFRIDPHDGQICVSQDIDRERDPATYDLL 136 Query: 657 AVAIDGGTPPQ----------SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706 A DG S+ V + +ED+ND+ PVF IS+ + GT I Sbjct: 137 VEAKDGDEQRMTHLALVKGGLSAQAFVRVDLEDVNDNHPVFNPSTYVTSISDETQPGTEI 196 Query: 707 GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG--SDKAELVTMVD 753 + A D D G V Y + G+ S+ F++++ G S + E+++ V+ Sbjct: 197 INVLATDQDSGIYGTVAYELIPGNVSSLFTIDSTTGLYSPEVEILSAVN 245 Score = 69.3 bits (162), Expect = 1e-09 Identities = 43/126 (34%), Positives = 63/126 (50%), Gaps = 10/126 (7%) Query: 90 FRIDGRSGALLTRASLDREK-VARYTVLVKATD-------QASPVSDRLSSTATIHVNII 141 FRID G + +DRE+ A Y +LV+A D + V LS+ A + V++ Sbjct: 109 FRIDPHDGQICVSQDIDRERDPATYDLLVEAKDGDEQRMTHLALVKGGLSAQAFVRVDLE 168 Query: 142 DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFS 201 D NDN+P F+ TY S+ ++ I + ATD D G + Y +I GN F+ Sbjct: 169 DVNDNHPVFNPSTYVTSISDE--TQPGTEIINVLATDQDSGIYGTVAYELIPGNVSSLFT 226 Query: 202 IDSLSG 207 IDS +G Sbjct: 227 IDSTTG 232 Score = 60.1 bits (139), Expect = 9e-07 Identities = 45/154 (29%), Positives = 63/154 (40%), Gaps = 13/154 (8%) Query: 279 VQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ-AKYQLLVT 337 V A DAD G+ + Y++ D + IDP G + S +DRE A Y LLV Sbjct: 79 VTASDADSGLYGFIEYSLYDGFLSYEAPQAFRIDPHDGQICVSQDIDRERDPATYDLLVE 138 Query: 338 ATDGGDPPR----------SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387 A DG + SA A F P Y ++++ PGT ++ Sbjct: 139 AKDGDEQRMTHLALVKGGLSAQAFVRVDLEDVNDNHPVFNPSTYVTSISDETQPGTEIIN 198 Query: 388 LTATDADED--NRLHYEITGGNTRGRFSITSQNG 419 + ATD D + YE+ GN F+I S G Sbjct: 199 VLATDQDSGIYGTVAYELIPGNVSSLFTIDSTTG 232 Score = 59.7 bits (138), Expect = 1e-06 Identities = 44/159 (27%), Positives = 72/159 (45%), Gaps = 19/159 (11%) Query: 173 KIKATDADVGANSAIRYAIIGG----NTQMQFSIDSLSGDVSLVKTLDYEQ-VRSYRLVI 227 ++ A+DAD G I Y++ G F ID G + + + +D E+ +Y L++ Sbjct: 78 EVTASDADSGLYGFIEYSLYDGFLSYEAPQAFRIDPHDGQICVSQDIDRERDPATYDLLV 137 Query: 228 RAQDGGSPSRSNTTQLL----------INIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277 A+DG ++ + +++ DVNDN P F S + S+S+ G I+ Sbjct: 138 EAKDGDEQRMTHLALVKGGLSAQAFVRVDLEDVNDNHPVFNPSTYVTSISDETQPGTEII 197 Query: 278 RVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316 V A D D G+ + Y + GNV TID +G Sbjct: 198 NVLATDQDSGIYGTVAYEL----IPGNVSSLFTIDSTTG 232 Score = 51.2 bits (117), Expect = 4e-04 Identities = 25/70 (35%), Positives = 38/70 (54%) Query: 439 LTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498 +T A GG S A V++++ D N+ PVF + Y S+ ++ GT ++ V ATD D Sbjct: 147 MTHLALVKGGLSAQAFVRVDLEDVNDNHPVFNPSTYVTSISDETQPGTEIINVLATDQDS 206 Query: 499 GINAQITYSL 508 GI + Y L Sbjct: 207 GIYGTVAYEL 216 Score = 41.5 bits (93), Expect = 0.32 Identities = 18/53 (33%), Positives = 29/53 (54%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 ++++ D ND+ PVF Y S+ + GT ++ + ATDQD G V Y + Sbjct: 164 RVDLEDVNDNHPVFNPSTYVTSISDETQPGTEIINVLATDQDSGIYGTVAYEL 216 >UniRef50_UPI0000F3174E Cluster: dachsous 2 isoform 1; n=9; Theria|Rep: dachsous 2 isoform 1 - Bos Taurus Length = 2131 Score = 351 bits (864), Expect = 1e-94 Identities = 266/871 (30%), Positives = 415/871 (47%), Gaps = 57/871 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIG-KNAEVEYTIELVTADT 69 + V D NDHSP F + SV E GT V A D D N+ ++Y IE Sbjct: 257 VAVEDQNDHSPSFREEFIVISVPENTPVGTLVHIFNAKDGDGSFLNSRIQYFIE-ANHPG 315 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 +NP F I SG L+T + LDRE+V + V A+DQA V+DR Sbjct: 316 MNP-----------------FLIHPSSGTLVTTSPLDRERVPTVVLTVTASDQAVNVTDR 358 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + V I+D ND+ P F+ V ED +V ++ I A D D G N + + Sbjct: 359 RLRSLMAKVVILDVNDHSPTFTSFPIA-HVREDAAV--GSLVHHITAQDPDAGRNGRVTF 415 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 +I+ GN M F +D SG ++ LDYE + L + A DGG+P+ S++ L I + D Sbjct: 416 SILSGNENMAFMLDESSGFLTTASPLDYEIKSQHILTLLALDGGTPTLSSSQTLTITVLD 475 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 VND AP F L++ SV EN G + RV+A D D G+N++L + + G + Sbjct: 476 VNDEAPVFKQHLYEASVKENQNPGEFVTRVEAVDRDSGINSKLQFEI----MPGASFMLF 531 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 I+ +G V T+ LDRE Q L V DGG P S T + Sbjct: 532 QINSDTGEVVTAATLDREVQEVLTLRVLVHDGGAPALSGTTVILCTVRDENDHAPQIVVP 591 Query: 370 QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 + ++E+ E++ PG V T A+D D + + Y I GNT F++ +G ++ + Sbjct: 592 RDDIEVLENQEPGL-VYTFLASDMDAGSNGAVTYHIIDGNTDEYFAVNEMSGE--LSTTR 648 Query: 428 PLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 LD ++ + L + +D G +S TA +Q+ + D N+++P F Y ASV EDA +G Sbjct: 649 ALDREEVSNFTLVILCSDLGSPPQSSTAQLQVRVLDDNDHSPSFPRLQYQASVREDAQVG 708 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 TTVLV+S+ D D G+N Q YSL E S F I+P G + T++ LDRE S Sbjct: 709 TTVLVLSSADEDEGLNGQTMYSLVHESSG--------AFTIDPVAGTLRTSRALDREARS 760 Query: 546 GYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 ++L ARD GV S S T +++ V DVNDN PV +Q + + + + + Sbjct: 761 EHVLKAVARDCGVQGSRSTTVVIKVHVTDVNDNSPVLEQNPLDIFLSSQSPTNQTAAILR 820 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 A+D D G NG + + + I+ +G I+ + E L+ A+D G Sbjct: 821 ASDPDSGPNGTVTFSF---AEPQSVLSINEYTGAIQLQQIPSSEYFPIW-LQLKAVDQGV 876 Query: 665 PPQSST--VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 P +++T +++H++ ED+ S F + EN GT+I I+A PD ++ + Sbjct: 877 PARTTTGLLVIHMEGEDVRIS---FSQHLYKGIVPENCEAGTSIVTIKAFAPDSIRDS-I 932 Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEI 782 YS+ G++ FSL ++ G + +D + RK+ +L++ A S +V + Sbjct: 933 KYSVFSGNEDGVFSLCSKSGEVTVKEPKFLDFEV---RKEVQLIVLAESRGRKAYSKVAV 989 Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNNANLI 840 + D+ND+ P + + + F +V A D D ++Y ILSGN N+ Sbjct: 990 FIQDLNDHPPHFEQSVYQVSVSEGQFYNHHIVQVFATDLDSGSNGLVEYSILSGNQGNVF 1049 Query: 841 LLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 ++ +G +T S L+ ++ V D Sbjct: 1050 QMDPLSGVLTASAILDYEYTSTYSLIVQAMD 1080 Score = 314 bits (770), Expect = 3e-83 Identities = 256/875 (29%), Positives = 412/875 (47%), Gaps = 75/875 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I VLD ND +PVF+ YEASV+E + G V ++A D+D G N+++++ I + A + Sbjct: 471 ITVLDVNDEAPVFKQHLYEASVKENQNPGEFVTRVEAVDRDSGINSKLQFEI-MPGASFM 529 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +F+I+ +G ++T A+LDRE T+ V D +P L Sbjct: 530 ------------------LFQINSDTGEVVTAATLDREVQEVLTLRVLVHDGGAPA---L 568 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP---VIAKIKATDADVGANSAI 187 S T I + D+ND+ PQ V +DI V +N ++ A+D D G+N A+ Sbjct: 569 SGTTVILCTVRDENDHAPQI------VVPRDDIEVLENQEPGLVYTFLASDMDAGSNGAV 622 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 Y II GNT F+++ +SG++S + LD E+V ++ LVI D GSP +S+T QL + + Sbjct: 623 TYHIIDGNTDEYFAVNEMSGELSTTRALDREEVSNFTLVILCSDLGSPPQSSTAQLQVRV 682 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 D ND++P F +Q SV E+ +G +++ + + D DEG+N + Y++ + +G Sbjct: 683 LDDNDHSPSFPRLQYQASVREDAQVGTTVLVLSSADEDEGLNGQTMYSLVHES-SG---- 737 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATD-GGDPPRSATATXXXXXXXXXXXXXXF 366 TIDP +G + TS LDRE ++++ L A D G RS T Sbjct: 738 AFTIDPVAGTLRTSRALDREARSEHVLKAVARDCGVQGSRSTTVVIKVHVTDVNDNSPVL 797 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 ++ L+ P L A+D D + + SI G Sbjct: 798 EQNPLDIFLSSQSPTNQTAAILRASDPDSGPNGTVTFSFAEPQSVLSINEYTG---AIQL 854 Query: 427 QPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 Q + + L + A D G R+ T ++ I++ + + F Y V E+ Sbjct: 855 QQIPSSEYFPIWLQLKAVDQGVPARTTTGLLVIHM-EGEDVRISFSQHLYKGIVPENCEA 913 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN--KLLDRE 542 GT+++ + A D I I YS+ S NE D F + ++G +T K LD E Sbjct: 914 GTSIVTIKAFAPD-SIRDSIKYSVFS--GNE-----DGVFSLCSKSGEVTVKEPKFLDFE 965 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 L V A G + S V + + D+ND+ P F+Q +Y ++ E + Q Sbjct: 966 VRKEVQLIVLAESRGRKAYS---KVAVFIQDLNDHPPHFEQSVYQVSVSEGQFYNHHIVQ 1022 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 V ATD D G NG + Y + + F +DP SGV+ + LD E +T+ L A+D Sbjct: 1023 VFATDLDSGSNGLVEYSI-LSGNQGNVFQMDPLSGVLTASAILDYEYTSTYSLIVQAMDK 1081 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVF-ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 G P S T ++ I++ DIND+ P+F S+ + I ENS GT + I +D D P A Sbjct: 1082 GMPRLSDTTVIKIQVTDINDNAPIFLPSEAVE--IVENSLPGTIVTRISVYDVDSNP-AF 1138 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781 +K + F+++ G +V + LD+E KYEL I+ + + V Sbjct: 1139 TFSFVKESNSGTKFAIDRNTG----VVVLVETLDFEE-ATKYELQIQISDLVHQTEGTVT 1193 Query: 782 ILVTDVNDNAPVMK--DFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNAN 838 + V DVNDN PV +Q+ + + P+G P + A D + ++ + YRILS ++ Sbjct: 1194 VHVLDVNDNPPVFSQDSYQVTIS---ELVPLGHPVLTIVATDVESSENITYRILS--SSK 1248 Query: 839 LILLNETTGSM-TLSPQLNTNVPKLATMEVSVTDG 872 + ++ T G++ T++P V +DG Sbjct: 1249 MFSVDPTNGTIFTINPVFLMERKSTIRFLVEASDG 1283 Score = 312 bits (765), Expect = 1e-82 Identities = 253/886 (28%), Positives = 404/886 (45%), Gaps = 66/886 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ +LD NDHSP F A VRE A+ G+ V + A D D G+N V ++I Sbjct: 366 KVVILDVNDHSPTFTSFPI-AHVREDAAVGSLVHHITAQDPDAGRNGRVTFSI------- 417 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L+ + F +D SG L T + LD E +++ + + A D +P Sbjct: 418 LSGNE------------NMAFMLDESSGFLTTASPLDYEIKSQHILTLLALDGGTPT--- 462 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LSS+ T+ + ++D ND P F + Y SV E + + +++A D D G NS +++ Sbjct: 463 LSSSQTLTITVLDVNDEAPVFKQHLYEASVKE--NQNPGEFVTRVEAVDRDSGINSKLQF 520 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I+ G + M F I+S +G+V TLD E L + DGG+P+ S TT +L +RD Sbjct: 521 EIMPGASFMLFQINSDTGEVVTAATLDREVQEVLTLRVLVHDGGAPALSGTTVILCTVRD 580 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 ND+AP+ V EN G + A D D G N +TY + D GN D Sbjct: 581 ENDHAPQIVVPRDDIEVLENQEPGL-VYTFLASDMDAGSNGAVTYHIID----GNTDEYF 635 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 ++ SG + T+ LDRE + + L++ +D G PP+S+TA F Sbjct: 636 AVNEMSGELSTTRALDREEVSNFTLVILCSDLGSPPQSSTAQLQVRVLDDNDHSPSFPRL 695 Query: 370 QYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 QY+ + ED GT V+ L++ D DE + + Y + + G F+I G + ++ Sbjct: 696 QYQASVREDAQVGTTVLVLSSADEDEGLNGQTMYSLV-HESSGAFTIDPV--AGTLRTSR 752 Query: 428 PLDFKQERRYVLTVSATD---SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 LD + +VL A D G RS T ++++++TD N+ +PV E P + +P Sbjct: 753 ALDREARSEHVLKAVARDCGVQGSRSTTVVIKVHVTDVNDNSPVLEQNPLDIFLSSQSPT 812 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 T ++ A+D D G N +T+S A IN TGAI ++ E Sbjct: 813 NQTAAILRASDPDSGPNGTVTFSF---------AEPQSVLSINEYTGAIQLQQIPSSEYF 863 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 + L + A D GVP+ + TT + + ++ D F Q LY + E+ GTS+ + Sbjct: 864 PIW-LQLKAVDQGVPART-TTGLLVIHMEGEDVRISFSQHLYKGIVPENCEAGTSIVTIK 921 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASG--VIRTNKALDRESVATHDLKAVAIDG 662 A D + I Y + E+G F + SG ++ K LD E L +A Sbjct: 922 AFAPD-SIRDSIKYSVF-SGNEDGVFSLCSKSGEVTVKEPKFLDFEVRKEVQLIVLAESR 979 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 G S V + I+D+ND PP FE +SE I ++ A D D G N +V Sbjct: 980 GRKAYSK---VAVFIQDLNDHPPHFEQSVYQVSVSEGQFYNHHIVQVFATDLDSGSNGLV 1036 Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVR 779 YSI G+ N F ++ G A + LDYE Y L+++A P L + Sbjct: 1037 EYSILSGNQGNVFQMDPLSGVLTASAI----LDYEY-TSTYSLIVQAMDKGMPRLSDTTV 1091 Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYR-ILSGNNAN 838 ++I VTD+NDNAP+ + + ++ P R+ YD D + + N+ Sbjct: 1092 IKIQVTDINDNAPIFLPSEAV-EIVENSLPGTIVTRISVYDVDSNPAFTFSFVKESNSGT 1150 Query: 839 LILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884 ++ TG + L L+ +++ ++D V++ + + + V Sbjct: 1151 KFAIDRNTGVVVLVETLDFEEATKYELQIQISDLVHQTEGTVTVHV 1196 Score = 283 bits (694), Expect = 5e-74 Identities = 262/866 (30%), Positives = 396/866 (45%), Gaps = 75/866 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 Q+ VLD NDHSP F QY+ASVRE A GTTVL L + D+D G N + Y++ ++ Sbjct: 679 QVRVLDDNDHSPSFPRLQYQASVREDAQVGTTVLVLSSADEDEGLNGQTMYSLVHESSGA 738 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 F ID +G L T +LDRE AR ++KA + V Sbjct: 739 --------------------FTIDPVAGTLRTSRALDRE--ARSEHVLKAVARDCGVQGS 776 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S+T I V++ D NDN P + + + S T N A ++A+D D G N + + Sbjct: 777 RSTTVVIKVHVTDVNDNSPVLEQNPLDIFLSSQ-SPT-NQTAAILRASDPDSGPNGTVTF 834 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 + Q SI+ +G + L + E + L ++A D G P+R+ T L+I++ Sbjct: 835 SF--AEPQSVLSINEYTGAIQLQQIPSSEYFPIW-LQLKAVDQGVPARTTTGLLVIHMEG 891 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 D F L++ V EN G SIV ++A+ A + + + Y++ ++GN D Sbjct: 892 -EDVRISFSQHLYKGIVPENCEAGTSIVTIKAF-APDSIRDSIKYSV----FSGNEDGVF 945 Query: 310 TIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 ++ +SG V LD E + + QL+V A G R A + F Sbjct: 946 SLCSKSGEVTVKEPKFLDFEVRKEVQLIVLAESRG---RKAYSKVAVFIQDLNDHPPHFE 1002 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITV 425 Y+V ++E + +V + ATD D + + Y I GN F + +G ++T Sbjct: 1003 QSVYQVSVSEGQFYNHHIVQVFATDLDSGSNGLVEYSILSGNQGNVFQMDPLSG--VLTA 1060 Query: 426 AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 + LD++ Y L V A D G SDT +++I +TD N+ AP+F + + E++ Sbjct: 1061 SAILDYEYTSTYSLIVQAMDKGMPRLSDTTVIKIQVTDINDNAPIFLPSE-AVEIVENSL 1119 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 GT V +S D D N T+S E SN +F I+ TG + + LD E Sbjct: 1120 PGTIVTRISVYDVDS--NPAFTFSFVKE-SNSGT-----KFAIDRNTGVVVLVETLDFEE 1171 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 + Y L + D + ++ T V + V+DVNDN PVF Q Y I E +G V + Sbjct: 1172 ATKYELQIQISD--LVHQTEGT-VTVHVLDVNDNPPVFSQDSYQVTISELVPLGHPVLTI 1228 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT-NKALDRESVATHDLKAVAIDG 662 ATD + N I Y + + F +DP +G I T N E +T A DG Sbjct: 1229 VATDVESSEN--ITYRILSSSK---MFSVDPTNGTIFTINPVFLMERKSTIRFLVEASDG 1283 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAV 721 G P + +V +I+D+N+ P F + +SE++P+G T+ D D N Sbjct: 1284 GFPDLKAVTLVETEIQDMNNYAPEFAIEYYNLSLSEDTPVGRTLVTFSTIDHDWTRENTH 1343 Query: 722 VHYSIKGGDDSNSFSLETR----QGSDK--AELVTMVDLDYESPRKKYELVIRA---ASP 772 V YSI G+ N+F +ET + S K LV + LD E+ +ELV+ A P Sbjct: 1344 VEYSIISGNSQNNFHVETSFIHSEYSYKQVGYLVLLHHLDREATAS-HELVLLAFDHGCP 1402 Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYR 830 PL + V I V DV+DN P + + + P P V A D DV ++ Y Sbjct: 1403 PLSSSATVSIEVLDVDDNPPAFSSLEYYVHIKESTPPGSPIIVVSASDRDVGSHAEVSYY 1462 Query: 831 ILSGNNANLILLNETTGSMTLSPQLN 856 + SGN L E TG ++L L+ Sbjct: 1463 LTSGNEKQHFCLEEKTGVLSLIKPLD 1488 Score = 279 bits (685), Expect = 6e-73 Identities = 238/802 (29%), Positives = 368/802 (45%), Gaps = 61/802 (7%) Query: 11 INVLDCNDHSPVFEM----QQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 ++V D ND+ P F ++ V EG V T+ A D D G NAEV Y++ Sbjct: 41 VSVTDINDNRPYFPQCLAGKELYVKVLEGQPVNMLVTTVFAKDLDEGNNAEVIYSV---- 96 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 + ED+ D F+ID SG + T L R+ Y + V A+DQ P Sbjct: 97 ----SSEDSS-----------DHFKIDANSGEIRTTRVLSRDYGPSYRMTVIASDQGVP- 140 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD-ADVGANS 185 L A I++ +I + S+ + + E++ T V++ IK+ D Sbjct: 141 --PLQGQAVINIQVIPLSKGRTVISQNIRHLVIPENLKPT--KVMSLIKSPDHLQRQHGG 196 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRL-VIRAQDGGSPSRSNTTQLL 244 + ++I + F +DS +GD+ L K LDYE + Y L V+ +P ++T L Sbjct: 197 KLHFSIAADDKDGHFEVDSSTGDLFLSKELDYEMMSHYLLRVVTKDHSRNPPVNSTVFLS 256 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG-VNAELTYTMTDKDYTG 303 + + D ND++P F SV EN P+G + A D D +N+ + Y + ++ G Sbjct: 257 VAVEDQNDHSPSFREEFIVISVPENTPVGTLVHIFNAKDGDGSFLNSRIQY-FIEANHPG 315 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG--GDPPRSATATXXXXXXXXXX 361 P I P SG + T+ LDRE L VTA+D R + Sbjct: 316 M--NPFLIHPSSGTLVTTSPLDRERVPTVVLTVTASDQAVNVTDRRLRSLMAKVVILDVN 373 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419 + ED G+ V +TA D D + R+ + I GN F + + Sbjct: 374 DHSPTFTSFPIAHVREDAAVGSLVHHITAQDPDAGRNGRVTFSILSGNENMAFMLDESS- 432 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477 G +T A PLD++ + +++LT+ A D G S + + I + D N+ APVF+ Y AS Sbjct: 433 -GFLTTASPLDYEIKSQHILTLLALDGGTPTLSSSQTLTITVLDVNDEAPVFKQHLYEAS 491 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 V E+ G V V A D D GIN+++ + + S F IN TG + T Sbjct: 492 VKENQNPGEFVTRVEAVDRDSGINSKLQFEIMPGAS-------FMLFQINSDTGEVVTAA 544 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LDRE L V DGG P+LS TT + +V D ND+ P ++E+ G Sbjct: 545 TLDREVQEVLTLRVLVHDGGAPALSGTTVILCTVRDENDHAPQIVVPRDDIEVLENQEPG 604 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 V A+D D G NG + Y + + +E F ++ SG + T +ALDRE V+ L Sbjct: 605 L-VYTFLASDMDAGSNGAVTYHIIDGNTDE-YFAVNEMSGELSTTRALDREEVSNFTLVI 662 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 + D G+PPQSST + +++ D ND P F + E++ +GTT+ + + D DEG Sbjct: 663 LCSDLGSPPQSSTAQLQVRVLDDNDHSPSFPRLQYQASVREDAQVGTTVLVLSSADEDEG 722 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND 777 N YS+ + S +F+++ G+ L T LD E+ R ++ L A + Sbjct: 723 LNGQTMYSLV-HESSGAFTIDPVAGT----LRTSRALDREA-RSEHVLKAVARDCGVQGS 776 Query: 778 ----VRVEILVTDVNDNAPVMK 795 V +++ VTDVNDN+PV++ Sbjct: 777 RSTTVVIKVHVTDVNDNSPVLE 798 Score = 279 bits (685), Expect = 6e-73 Identities = 244/839 (29%), Positives = 382/839 (45%), Gaps = 74/839 (8%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72 V D NDH+P + + + V E G V T A+D D G N V Y I + +T Sbjct: 578 VRDENDHAPQIVVPRDDIEVLENQEPGL-VYTFLASDMDAGSNGAVTYHI--IDGNT--- 631 Query: 73 EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132 + F ++ SG L T +LDRE+V+ +T+++ +D SP SS Sbjct: 632 --------------DEYFAVNEMSGELSTTRALDREEVSNFTLVILCSDLGSPPQ---SS 674 Query: 133 TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192 TA + V ++DDND+ P F Y SV ED V + + + D D G N Y+++ Sbjct: 675 TAQLQVRVLDDNDHSPSFPRLQYQASVREDAQV--GTTVLVLSSADEDEGLNGQTMYSLV 732 Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD-GGSPSRSNTTQLLINIRDVN 251 + F+ID ++G + + LD E + L A+D G SRS T + +++ DVN Sbjct: 733 -HESSGAFTIDPVAGTLRTSRALDREARSEHVLKAVARDCGVQGSRSTTVVIKVHVTDVN 791 Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311 DN+P + +S P + ++A D D G N +T++ + ++I Sbjct: 792 DNSPVLEQNPLDIFLSSQSPTNQTAAILRASDPDSGPNGTVTFSFAEPQSV------LSI 845 Query: 312 DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371 + +G + Q+ L + A D G P R+ T F Y Sbjct: 846 NEYTGAIQLQ-QIPSSEYFPIWLQLKAVDQGVPARTTTG-LLVIHMEGEDVRISFSQHLY 903 Query: 372 EVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQP-- 428 + + E+ GT +VT+ A D + + Y + GN G FS+ S++G +TV +P Sbjct: 904 KGIVPENCEAGTSIVTIKAFAPDSIRDSIKYSVFSGNEDGVFSLCSKSGE--VTVKEPKF 961 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 LDF+ + L V A +S GR + V + I D N++ P FE + Y SV E + Sbjct: 962 LDFEVRKEVQLIVLA-ESRGRKAYSKVAVFIQDLNDHPPHFEQSVYQVSVSEGQFYNHHI 1020 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 + V ATD D G N + YS+ S + F ++P +G +T + +LD E S Y Sbjct: 1021 VQVFATDLDSGSNGLVEYSILS-------GNQGNVFQMDPLSGVLTASAILDYEYTSTYS 1073 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 L V A D G+P LSDTT ++I V D+NDN P+F I+E++L GT V+++ D Sbjct: 1074 LIVQAMDKGMPRLSDTTVIKIQVTDINDNAPIFLPS-EAVEIVENSLPGTIVTRISVYDV 1132 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 D N + + F ID +GV+ + LD E ++L+ + I Sbjct: 1133 D--SNPAFTFSFVKESNSGTKFAIDRNTGVVVLVETLDFEEATKYELQ-IQISDLVHQTE 1189 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 TV VH+ D+ND+PPVF D ISE P+G + I A D + N + Y I Sbjct: 1190 GTVTVHVL--DVNDNPPVFSQDSYQVTISELVPLGHPVLTIVATDVESSEN--ITYRIL- 1244 Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVT 785 S FS++ G+ + T+ + + ++ A+ P L VE + Sbjct: 1245 -SSSKMFSVDPTNGT----IFTINPVFLMERKSTIRFLVEASDGGFPDLKAVTLVETEIQ 1299 Query: 786 DVNDNAPVMKDFQIIFNN--YKDCFPVG-PFGRVPAYDADVTDK---LQYRILSGNNAN 838 D+N+ AP +F I + N + PVG D D T + ++Y I+SGN+ N Sbjct: 1300 DMNNYAP---EFAIEYYNLSLSEDTPVGRTLVTFSTIDHDWTRENTHVEYSIISGNSQN 1355 Score = 277 bits (679), Expect = 3e-72 Identities = 220/753 (29%), Positives = 351/753 (46%), Gaps = 72/753 (9%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72 + D NDH P FE Y+ SV EG ++ + ATD D G N VEY+I L+ Sbjct: 991 IQDLNDHPPHFEQSVYQVSVSEGQFYNHHIVQVFATDLDSGSNGLVEYSI-------LSG 1043 Query: 73 EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132 +VF++D SG L A LD E + Y+++V+A D+ P RLS Sbjct: 1044 NQG------------NVFQMDPLSGVLTASAILDYEYTSTYSLIVQAMDKGMP---RLSD 1088 Query: 133 TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192 T I + + D NDN P F V+ + T ++ +I D D +N A ++ + Sbjct: 1089 TTVIKIQVTDINDNAPIFLPSEAVEIVENSLPGT---IVTRISVYDVD--SNPAFTFSFV 1143 Query: 193 G-GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251 N+ +F+ID +G V LV+TLD+E+ Y L I+ D + T +++ DVN Sbjct: 1144 KESNSGTKFAIDRNTGVVVLVETLDFEEATKYELQIQISDLVHQTEGTVT---VHVLDVN 1200 Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311 DN P F +Q ++SE VP+G+ ++ + A D + N +TY + ++ Sbjct: 1201 DNPPVFSQDSYQVTISELVPLGHPVLTIVATDVESSEN--ITYRILSSSKM------FSV 1252 Query: 312 DPRSGWVYTSGQLD-RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 DP +G ++T + E ++ + LV A+DGG P A F Sbjct: 1253 DPTNGTIFTINPVFLMERKSTIRFLVEASDGGFPDLKAVTLVETEIQDMNNYAPEFAIEY 1312 Query: 371 YEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSIT--------SQNG 419 Y + L+ED P G +VT + D D E+ + Y I GN++ F + S Sbjct: 1313 YNLSLSEDTPVGRTLVTFSTIDHDWTRENTHVEYSIISGNSQNNFHVETSFIHSEYSYKQ 1372 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477 G + + LD + + L + A D G S +A V I + D ++ P F + Y Sbjct: 1373 VGYLVLLHHLDREATASHELVLLAFDHGCPPLSSSATVSIEVLDVDDNPPAFSSLEYYVH 1432 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 + E P G+ ++VVSA+D DVG +A+++Y L+S NE Q F + +TG ++ K Sbjct: 1433 IKESTPPGSPIIVVSASDRDVGSHAEVSYYLTS--GNEK-----QHFCLEEKTGVLSLIK 1485 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LD E ++LTV A D S V ++V+D ND+ P F + E+ V Sbjct: 1486 PLDYEETIKFILTVQASDEERKHFSFAI-VFVNVLDDNDHAPQFMFPNLNCAVPENLPVF 1544 Query: 598 TSVSQVGATDADVGLNGRIHYELD-----PKD--REEGSFVIDPASGVIRTNKALDRESV 650 +++ V A D D G G + Y + P + + F+IDP +G I + LD E+ Sbjct: 1545 STICSVNALDFDAGPYGDMTYSIVSPCPLPHEMPHDHNFFLIDPLTGDISAQQVLDYEND 1604 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710 + L A D +++V+V + +E I++ P+F D F + E S + IG + Sbjct: 1605 NKYCLIVQAKDKAD--STASVVVWVDVEGIDEFEPIFTQDQYFFSLPEKSHVRHLIGRVE 1662 Query: 711 AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 A D D G + V+ YS++ S FS+ G+ Sbjct: 1663 ASDADAGVDGVILYSLE--TPSPFFSVNKTNGN 1693 Score = 270 bits (661), Expect = 5e-70 Identities = 231/799 (28%), Positives = 370/799 (46%), Gaps = 72/799 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +++V D ND+SPV E + + + + T L+A+D D G N V ++ Sbjct: 784 KVHVTDVNDNSPVLEQNPLDIFLSSQSPTNQTAAILRASDPDSGPNGTVTFSFA------ 837 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 P Q V I+ +GA+ + E + L KA DQ P Sbjct: 838 -EP--------------QSVLSINEYTGAIQLQQIPSSEYFPIWLQL-KAVDQGVPAR-- 879 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 +T + V ++ D FS+ Y V E+ + V K A D+ +I+Y Sbjct: 880 --TTTGLLVIHMEGEDVRISFSQHLYKGIVPENCEAGTSIVTIKAFAPDS---IRDSIKY 934 Query: 190 AIIGGNTQMQFSIDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 ++ GN FS+ S SG+V++ K LD+E + +L++ A+ G R +++ + I Sbjct: 935 SVFSGNEDGVFSLCSKSGEVTVKEPKFLDFEVRKEVQLIVLAESRG---RKAYSKVAVFI 991 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 +D+ND+ P F S++Q SVSE + IV+V A D D G N + Y++ + GNV Sbjct: 992 QDLNDHPPHFEQSVYQVSVSEGQFYNHHIVQVFATDLDSGSNGLVEYSILSGNQ-GNV-- 1048 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 +DP SG + S LD E + Y L+V A D G P S T F+ Sbjct: 1049 -FQMDPLSGVLTASAILDYEYTSTYSLIVQAMDKGMPRLSDTTVIKIQVTDINDNAPIFL 1107 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYE-ITGGNTRGRFSITSQNGRGLITVA 426 P + VE+ E+ PGT V ++ D D + + + N+ +F+I G++ + Sbjct: 1108 PSE-AVEIVENSLPGTIVTRISVYDVDSNPAFTFSFVKESNSGTKFAI--DRNTGVVVLV 1164 Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 + LDF++ +Y L + +D +++ V +++ D N+ PVF Y ++ E P+G Sbjct: 1165 ETLDFEEATKYELQIQISDLVHQTE-GTVTVHVLDVNDNPPVFSQDSYQVTISELVPLGH 1223 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKLLDRETMS 545 VL + ATD + N ITY + S + F ++P G I T N + E S Sbjct: 1224 PVLTIVATDVESSEN--ITYRILSS---------SKMFSVDPTNGTIFTINPVFLMERKS 1272 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 V A DGG P L T VE + D+N+ P F + Y ++ ED VG ++ Sbjct: 1273 TIRFLVEASDGGFPDLKAVTLVETEIQDMNNYAPEFAIEYYNLSLSEDTPVGRTLVTFST 1332 Query: 606 TDAD-VGLNGRIHYELDPKDRE-----EGSFVIDPAS----GVIRTNKALDRESVATHDL 655 D D N + Y + + + E SF+ S G + LDRE+ A+H+L Sbjct: 1333 IDHDWTRENTHVEYSIISGNSQNNFHVETSFIHSEYSYKQVGYLVLLHHLDREATASHEL 1392 Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 +A D G PP SS+ V I++ D++D+PP F S +I E++P G+ I + A D D Sbjct: 1393 VLLAFDHGCPPLSSSATVSIEVLDVDDNPPAFSSLEYYVHIKESTPPGSPIIVVSASDRD 1452 Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL- 774 G +A V Y + G++ F LE + G L + LDYE K+ L ++A+ Sbjct: 1453 VGSHAEVSYYLTSGNEKQHFCLEEKTG----VLSLIKPLDYEE-TIKFILTVQASDEERK 1507 Query: 775 -WNDVRVEILVTDVNDNAP 792 ++ V + V D ND+AP Sbjct: 1508 HFSFAIVFVNVLDDNDHAP 1526 Score = 266 bits (652), Expect = 6e-69 Identities = 223/779 (28%), Positives = 363/779 (46%), Gaps = 50/779 (6%) Query: 96 SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSE--- 152 SG L++ +LD E+ A + V V +D SP S+T +HV++ D NDN P F + Sbjct: 2 SGELISWVALDHEQRAHHQVAVLVSDHGSPPR---SATTLVHVSVTDINDNRPYFPQCLA 58 Query: 153 -KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSL 211 K V V E V N ++ + A D D G N+ + Y++ ++ F ID+ SG++ Sbjct: 59 GKELYVKVLEGQPV--NMLVTTVFAKDLDEGNNAEVIYSVSSEDSSDHFKIDANSGEIRT 116 Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271 + L + SYR+ + A D G P + I + ++ ++ + EN+ Sbjct: 117 TRVLSRDYGPSYRMTVIASDQGVPPLQGQAVINIQVIPLSKGRTVISQNIRHLVIPENLK 176 Query: 272 IGYSIVRVQAYD-ADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA 330 + +++ D +L +++ D G+ + +D +G ++ S +LD E + Sbjct: 177 PTKVMSLIKSPDHLQRQHGGKLHFSIAADDKDGHFE----VDSSTGDLFLSKELDYEMMS 232 Query: 331 KYQL-LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389 Y L +VT +PP ++T F + + E+ P GT V Sbjct: 233 HYLLRVVTKDHSRNPPVNSTVFLSVAVEDQNDHSPSFREEFIVISVPENTPVGTLVHIFN 292 Query: 390 ATDADE---DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD- 445 A D D ++R+ Y I N G G + PLD ++ VLTV+A+D Sbjct: 293 AKDGDGSFLNSRIQYFIE-ANHPGMNPFLIHPSSGTLVTTSPLDRERVPTVVLTVTASDQ 351 Query: 446 ----SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501 + R + M ++ I D N+++P F + P A V EDA +G+ V ++A D D G N Sbjct: 352 AVNVTDRRLRSLMAKVVILDVNDHSPTFTSFP-IAHVREDAAVGSLVHHITAQDPDAGRN 410 Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL 561 ++T+S+ S NE +A F+++ +G +TT LD E S ++LT+ A DGG P+L Sbjct: 411 GRVTFSILS--GNENMA-----FMLDESSGFLTTASPLDYEIKSQHILTLLALDGGTPTL 463 Query: 562 SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621 S + + I+V+DVND PVFKQ LY A++ E+ G V++V A D D G+N ++ +E+ Sbjct: 464 SSSQTLTITVLDVNDEAPVFKQHLYEASVKENQNPGEFVTRVEAVDRDSGINSKLQFEIM 523 Query: 622 PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681 P F I+ +G + T LDRE L+ + DGG P S T ++ + D N Sbjct: 524 P-GASFMLFQINSDTGEVVTAATLDREVQEVLTLRVLVHDGGAPALSGTTVILCTVRDEN 582 Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741 D P + EN G + A D D G N V Y I G+ F++ Sbjct: 583 DHAPQIVVPRDDIEVLENQEPG-LVYTFLASDMDAGSNGAVTYHIIDGNTDEYFAVNEMS 641 Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQ 798 G EL T LD E + LVI + SPP + ++++ V D ND++P Q Sbjct: 642 G----ELSTTRALDREEV-SNFTLVILCSDLGSPPQSSTAQLQVRVLDDNDHSPSFPRLQ 696 Query: 799 IIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNT 857 + +D VG V + AD + L + + L++E++G+ T+ P T Sbjct: 697 YQASVREDA-QVGTTVLVLS-SADEDEGLNGQTMYS------LVHESSGAFTIDPVAGT 747 Score = 256 bits (628), Expect = 5e-66 Identities = 202/706 (28%), Positives = 325/706 (46%), Gaps = 44/706 (6%) Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL---- 261 SG++ LD+EQ +++ + D GSP RS TT + +++ D+NDN P F L Sbjct: 2 SGELISWVALDHEQRAHHQVAVLVSDHGSPPRSATTLVHVSVTDINDNRPYFPQCLAGKE 61 Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321 V E P+ + V A D DEG NAE+ Y+++ +D + + ID SG + T+ Sbjct: 62 LYVKVLEGQPVNMLVTTVFAKDLDEGNNAEVIYSVSSEDSSDH----FKIDANSGEIRTT 117 Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381 L R+ Y++ V A+D G PP A + + E+ P Sbjct: 118 RVLSRDYGPSYRMTVIASDQGVPPLQGQAVINIQVIPLSKGRTVISQNIRHLVIPENLKP 177 Query: 382 GTPVVTLTAT----DADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437 T V++L + +LH+ I + G F + S G + +++ LD++ Y Sbjct: 178 -TKVMSLIKSPDHLQRQHGGKLHFSIAADDKDGHFEVDSSTGD--LFLSKELDYEMMSHY 234 Query: 438 VLTVSATDSGGR---SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494 +L V D + T + + + D N+++P F SV E+ P+GT V + +A Sbjct: 235 LLRVVTKDHSRNPPVNSTVFLSVAVEDQNDHSPSFREEFIVISVPENTPVGTLVHIFNAK 294 Query: 495 DSDVG-INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553 D D +N++I Y + EA F+I+P +G + T LDRE + +LTVTA Sbjct: 295 DGDGSFLNSRIQYFI------EANHPGMNPFLIHPSSGTLVTTSPLDRERVPTVVLTVTA 348 Query: 554 RDGGVPSLSD----TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 D V +++D + ++ ++DVND+ P F A++ EDA VG+ V + A D D Sbjct: 349 SDQAV-NVTDRRLRSLMAKVVILDVNDHSPTF-TSFPIAHVREDAAVGSLVHHITAQDPD 406 Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669 G NGR+ + + E +F++D +SG + T LD E + H L +A+DGGTP SS Sbjct: 407 AGRNGRVTFSI-LSGNENMAFMLDESSGFLTTASPLDYEIKSQHILTLLALDGGTPTLSS 465 Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729 + + I + D+ND PVF+ + EN G + + A D D G N+ + + I G Sbjct: 466 SQTLTITVLDVNDEAPVFKQHLYEASVKENQNPGEFVTRVEAVDRDSGINSKLQFEIMPG 525 Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYESPR--KKYELVIRAASPPLWNDVRVEILVTDV 787 F + SD E+VT LD E LV +P L + V D Sbjct: 526 ASFMLFQI----NSDTGEVVTAATLDREVQEVLTLRVLVHDGGAPALSGTTVILCTVRDE 581 Query: 788 NDNAP---VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNE 844 ND+AP V +D + N + V F DA + Y I+ GN +NE Sbjct: 582 NDHAPQIVVPRDDIEVLENQEPGL-VYTF-LASDMDAGSNGAVTYHIIDGNTDEYFAVNE 639 Query: 845 TTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITE 889 +G ++ + L+ T+ + +D G + QL VR++ + Sbjct: 640 MSGELSTTRALDREEVSNFTLVILCSDLGSPPQSSTAQLQVRVLDD 685 Score = 241 bits (589), Expect = 3e-61 Identities = 180/648 (27%), Positives = 317/648 (48%), Gaps = 52/648 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I V D ND++P+F + + E + GT V + D D + +T V Sbjct: 1093 KIQVTDINDNAPIF-LPSEAVEIVENSLPGTIVTRISVYDVD----SNPAFTFSFVKESN 1147 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + F ID +G ++ +LD E+ +Y + ++ +D + + Sbjct: 1148 SGTK----------------FAIDRNTGVVVLVETLDFEEATKYELQIQISD----LVHQ 1187 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 T T+HV +D NDN P FS+ +Y V++ E + + +PV+ I ATD + N I Y Sbjct: 1188 TEGTVTVHV--LDVNDNPPVFSQDSYQVTISELVPL-GHPVLT-IVATDVESSEN--ITY 1241 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDY-EQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 I+ ++ FS+D +G + + + E+ + R ++ A DGG P T + I+ Sbjct: 1242 RIL--SSSKMFSVDPTNGTIFTINPVFLMERKSTIRFLVEASDGGFPDLKAVTLVETEIQ 1299 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD---EGVNAELTYTMTDKDYTGNV 305 D+N+ AP F + S+SE+ P+G ++V D D E + E + + +V Sbjct: 1300 DMNNYAPEFAIEYYNLSLSEDTPVGRTLVTFSTIDHDWTRENTHVEYSIISGNSQNNFHV 1359 Query: 306 DLPITIDPRS----GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 + S G++ LDRE A ++L++ A D G PP S++AT Sbjct: 1360 ETSFIHSEYSYKQVGYLVLLHHLDREATASHELVLLAFDHGCPPLSSSATVSIEVLDVDD 1419 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNG 419 F +Y V + E PPG+P++ ++A+D D + + Y +T GN + F + + G Sbjct: 1420 NPPAFSSLEYYVHIKESTPPGSPIIVVSASDRDVGSHAEVSYYLTSGNEKQHFCLEEKTG 1479 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDT-AMVQINITDANNYAPVFENAPYTASV 478 ++++ +PLD+++ +++LTV A+D + + A+V +N+ D N++AP F +V Sbjct: 1480 --VLSLIKPLDYEETIKFILTVQASDEERKHFSFAIVFVNVLDDNDHAPQFMFPNLNCAV 1537 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ-FVINPQTGAITTNK 537 E+ P+ +T+ V+A D D G +TYS+ S HD F+I+P TG I+ + Sbjct: 1538 PENLPVFSTICSVNALDFDAGPYGDMTYSIVSPCPLPHEMPHDHNFFLIDPLTGDISAQQ 1597 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 +LD E + Y L V A+D + S V++ +D + EP+F Q Y ++ E + V Sbjct: 1598 VLDYENDNKYCLIVQAKDKADSTASVVVWVDVEGID--EFEPIFTQDQYFFSLPEKSHVR 1655 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645 + +V A+DAD G++G I Y L + F ++ +G I ++AL Sbjct: 1656 HLIGRVEASDADAGVDGVILYSL---ETPSPFFSVNKTNGNIYLSRAL 1700 Score = 150 bits (364), Expect = 5e-34 Identities = 118/428 (27%), Positives = 197/428 (46%), Gaps = 28/428 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTAD 68 + + D N+++P F ++ Y S+ E G T++T D D +N VEY+I ++ + Sbjct: 1295 ETEIQDMNNYAPEFAIEYYNLSLSEDTPVGRTLVTFSTIDHDWTRENTHVEYSI--ISGN 1352 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 + N + V G L+ LDRE A + +++ A D P Sbjct: 1353 SQNNFHVETSFIHSEYSYKQV-------GYLVLLHHLDREATASHELVLLAFDHGCP--- 1402 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 LSS+AT+ + ++D +DN P FS Y V + E + +P+I + A+D DVG+++ + Sbjct: 1403 PLSSSATVSIEVLDVDDNPPAFSSLEYYVHIKES-TPPGSPIIV-VSASDRDVGSHAEVS 1460 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y + GN + F ++ +G +SL+K LDYE+ + L ++A D + + +N+ Sbjct: 1461 YYLTSGNEKQHFCLEEKTGVLSLIKPLDYEETIKFILTVQASD-EERKHFSFAIVFVNVL 1519 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D ND+AP+F +V EN+P+ +I V A D D G ++TY++ + ++P Sbjct: 1520 DDNDHAPQFMFPNLNCAVPENLPVFSTICSVNALDFDAGPYGDMTYSIVSPCPLPH-EMP 1578 Query: 309 -----ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 IDP +G + LD E KY L+V A D D +A+ Sbjct: 1579 HDHNFFLIDPLTGDISAQQVLDYENDNKYCLIVQAKDKAD--STASVVVWVDVEGIDEFE 1636 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRG 421 F QY L E + + A+DAD D + Y + FS+ NG Sbjct: 1637 PIFTQDQYFFSLPEKSHVRHLIGRVEASDADAGVDGVILYSLE--TPSPFFSVNKTNGNI 1694 Query: 422 LITVAQPL 429 ++ A PL Sbjct: 1695 YLSRALPL 1702 Score = 82.2 bits (194), Expect = 2e-13 Identities = 61/230 (26%), Positives = 100/230 (43%), Gaps = 11/230 (4%) Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT- 693 +SG + + ALD E A H + + D G+PP+S+T +VH+ + DIND+ P F CL Sbjct: 1 SSGELISWVALDHEQRAHHQVAVLVSDHGSPPRSATTLVHVSVTDINDNRPYF-PQCLAG 59 Query: 694 --FYIS--ENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV 749 Y+ E P+ + + A D DEG NA V YS+ D S+ F ++ G + V Sbjct: 60 KELYVKVLEGQPVNMLVTTVFAKDLDEGNNAEVIYSVSSEDSSDHFKIDANSGEIRTTRV 119 Query: 750 TMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKD---FQIIFNNYKD 806 + DY + + PPL + I V ++ V+ +I N K Sbjct: 120 --LSRDYGPSYRMTVIASDQGVPPLQGQAVINIQVIPLSKGRTVISQNIRHLVIPENLKP 177 Query: 807 CFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 + KL + I + + ++ +TG + LS +L+ Sbjct: 178 TKVMSLIKSPDHLQRQHGGKLHFSIAADDKDGHFEVDSSTGDLFLSKELD 227 >UniRef50_UPI000069E6F8 Cluster: dachsous 2 isoform 1; n=1; Xenopus tropicalis|Rep: dachsous 2 isoform 1 - Xenopus tropicalis Length = 2689 Score = 349 bits (859), Expect = 5e-94 Identities = 271/871 (31%), Positives = 407/871 (46%), Gaps = 57/871 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIG-KNAEVEYTIELVTADT 69 I + D NDH P+F V E GT + T KA D+D +N+++ Y+ Sbjct: 824 IYIEDTNDHRPLFPDHIIVLGVDEDVPVGTLLYTFKANDKDGSLENSKIRYS-------- 875 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 LN ++ F I GAL T LDRE + + V ATDQA+ +S R Sbjct: 876 LNTHGTG----------ENPFFIHEWEGALTTANELDREMAESFVLTVTATDQAANISHR 925 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 ++ + + I D NDN PQ SV ED + ++ +I A D D G N I + Sbjct: 926 RCTSVIVRIVIQDINDNSPQVLSLP-VASVMEDAQI--GSLVHRIVAKDPDEGRNGKIGF 982 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I GN Q F +D +G ++L +D E Y L I A D G PS S T L I++ D Sbjct: 983 HIKEGNAQQVFLLDETTGWLTLHSEIDREVQDHYILTILALDDGIPSLSVTQTLTISLID 1042 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 VND P F L++ +V EN G +++V A D D G N+ LTY + G+ Sbjct: 1043 VNDKTPTFTQGLYEAAVPENQDPGLYVIKVAAVDYDLGNNSVLTYEILPGPAYGH----F 1098 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 I+P +G + T+ DRE Q ++ + V DGG PP S+T + Sbjct: 1099 RINPETGELVTTTVFDREQQDRFIIEVLVKDGGSPPLSSTTAILCSILDENDHTPEVLFP 1158 Query: 370 QYEVELAEDEPPGTPVVTLTA-TDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 E+ + E++ G L A DA + RLH++IT GN G F+I + +G+ + + Sbjct: 1159 DVEIRVPENQDLGIIHTVLAADKDAGNNGRLHFQITDGNMGGYFAINNTSGQ--LWATRT 1216 Query: 429 LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD + + +TV D G RS A ++I + D N+ P F + Y V ED IG+ Sbjct: 1217 LDREDFSSFTITVECHDLGTPHRSTIAKLRITVLDENDNPPTFPKSQYRTLVREDLKIGS 1276 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 VL + A+D+D G+N +I YSL + F +N TG I T + LDRE Sbjct: 1277 AVLKLQASDADEGLNKEIMYSLIDDTQG--------AFTVNRTTGNIVTIRTLDREVKHQ 1328 Query: 547 YLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 Y+ V A D + + S T V + + DVNDN PVF + I L +++ V A Sbjct: 1329 YVFRVVASDCSLRNPKSATVKVLVYIEDVNDNSPVFTENPIHVLISPKVLENKTIANVHA 1388 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 +D D+GLNG + Y L + F I G ++ L E +T L+ A D G P Sbjct: 1389 SDVDLGLNGTVVYNL---IKSNPFFYITQEKGEVKLQMPLPAEFSST-VLQVQASDLGIP 1444 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA--HDPDEGPNAVVH 723 P + T +V I I+ + D F + I ENS GT + ++A H+P++ ++H Sbjct: 1445 PNTVTGLVIIDIQGL-DKEIAFVHNFYEAIILENSEAGTLVVTVKALYHNPND---EIIH 1500 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEIL 783 Y++ GD +F+L G + + LD+E+ K+ L+I A S RV + Sbjct: 1501 YTVFSGDKKGAFNLNPITGDLMVKEPRL--LDFETV-NKFNLIISAESSQYTTYCRVTVF 1557 Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDAD--VTDKLQYRILSGNNANLI 840 + D NDNAPV I + + P F +V A D D + ++ Y I+SGN N Sbjct: 1558 IQDDNDNAPVFDQLDYI-SFVSEGQPFNTFVIQVFAADGDSGINGQIDYSIISGNENNAF 1616 Query: 841 LLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 +L+ G ++ + L+ + + V TD Sbjct: 1617 VLDSRHGILSTNVILDREIKSSYRLTVQATD 1647 Score = 297 bits (728), Expect = 4e-78 Identities = 248/813 (30%), Positives = 386/813 (47%), Gaps = 70/813 (8%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72 + D ND++PVF+ Y + V EG T V+ + A D D G N +++Y+I ++ + N Sbjct: 1558 IQDDNDNAPVFDQLDYISFVSEGQPFNTFVIQVFAADGDSGINGQIDYSI--ISGNENN- 1614 Query: 73 EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132 F +D R G L T LDRE + Y + V+ATD+ SP SS Sbjct: 1615 ----------------AFVLDSRHGILSTNVILDREIKSSYRLTVQATDRGSP---SCSS 1655 Query: 133 TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192 T+ + V I+D NDN P TV + ED + + I I A D D+ + + + Sbjct: 1656 TSVVTVLILDINDNAPTIPPMN-TVLIAEDAAPGYS--IGSISANDVDLRPDLSYTFTE- 1711 Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252 GN ++F+ID SG ++L ++LDYE+ + L I+A D + + +L+I + DVND Sbjct: 1712 NGNPGLKFAIDRYSGIITLTESLDYEESSQHCLRIQASDSVYHTEA---ELIIKVLDVND 1768 Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312 N P F ++++ ++ E I V A D D + +TY + G V + Sbjct: 1769 NPPVFTQNIYKVALPELTESNTFITTVSATDQDSEIYGPITYKIISP-LKGFVINTTSGK 1827 Query: 313 PRSGWVYTSGQLDRETQA-KYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371 RS VYT L +E ++ + Q+L+ A D G PP ++TA F Y Sbjct: 1828 LRS--VYTDMPLGKENKSTEIQILIVAMDNGSPPLTSTAMLSVTILDVNNYAPTFSEDIY 1885 Query: 372 EVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQNG--------R 420 V ++ED G V+TLTA D D ++ + + I GGN F + S Sbjct: 1886 YVNVSEDALVGDTVLTLTAMDLDWSPKNALIDFSIIGGNAHNLFYLESSEVLSHIPFIVT 1945 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASV 478 G + + QPLDF+ + L + ++ G + +A + INI D+N+ P+F N+ Y SV Sbjct: 1946 GKLIINQPLDFEVASAHRLDIFVSNQGFPPLNSSATIIINILDSNDNPPLFSNSEYHVSV 2005 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 E P+ +T++++SATDSD G NA ITYS+ S + + F I+ Q G +T + Sbjct: 2006 REHYPLKSTIIIISATDSDTGENADITYSIVS-------GNDENVFTIDAQNGTVTLVQP 2058 Query: 539 LDRETMSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LD E Y LT+ ARDG G + I+V+D ND P F Q + NI E+ Sbjct: 2059 LDYEETMKYSLTLQARDGHGSKRNVAFALLSITVLDENDFAPKFLFQSQSCNIYENVPFF 2118 Query: 598 TSVSQVGATDADVGLNGRIHYELDPK----DREEGSFVIDPASGVIRTNKALDRESVATH 653 + V V A D D G G + + + + +F+ID +G I T +D E H Sbjct: 2119 SPVCSVNAIDLDSGQYGILSFSIQSSCFNDQQHPATFLIDSLTGDIYTKHRIDYEMQERH 2178 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713 L D S+ V+V+I IE ++ PVF + F + E + G IG++ A D Sbjct: 2179 CLVVQVKDRSE--SSACVLVYIDIEGEDEFQPVFYQNQYLFDLPEENIGGQEIGKVGALD 2236 Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV---IRAA 770 DEG + VVHY ++ S FS+ G L V + RK E + ++A Sbjct: 2237 NDEGLDGVVHYFLE--KPSQFFSINMTSG--MIYLTRTVHKKRSNTRKNDEFIEFHVKAH 2292 Query: 771 SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN 803 SP D + + VN ++ ++D+ ++ N Sbjct: 2293 SPKF--DSKSAMCTVRVNISS-ALEDYPVMSAN 2322 Score = 296 bits (726), Expect = 6e-78 Identities = 248/851 (29%), Positives = 399/851 (46%), Gaps = 72/851 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+++D ND +P F YEA+V E G V+ + A D D+G N+ + Y I Sbjct: 1038 ISLIDVNDKTPTFTQGLYEAAVPENQDPGLYVIKVAAVDYDLGNNSVLTYEIL------- 1090 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P A FRI+ +G L+T DRE+ R+ + V D SP L Sbjct: 1091 -PGPAYGH-----------FRINPETGELVTTTVFDREQQDRFIIEVLVKDGGSPP---L 1135 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SST I +I+D+ND+ P+ + V E+ D +I + A D D G N + + Sbjct: 1136 SSTTAILCSILDENDHTPEVLFPDVEIRVPEN---QDLGIIHTVLAADKDAGNNGRLHFQ 1192 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I GN F+I++ SG + +TLD E S+ + + D G+P RS +L I + D Sbjct: 1193 ITDGNMGGYFAINNTSGQLWATRTLDREDFSSFTITVECHDLGTPHRSTIAKLRITVLDE 1252 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F S ++ V E++ IG +++++QA DADEG+N E+ Y++ D D G T Sbjct: 1253 NDNPPTFPKSQYRTLVREDLKIGSAVLKLQASDADEGLNKEIMYSLID-DTQG----AFT 1307 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPPRSATATXXXXXXXXXXXXXXFMPG 369 ++ +G + T LDRE + +Y V A+D P+SAT F Sbjct: 1308 VNRTTGNIVTIRTLDREVKHQYVFRVVASDCSLRNPKSATVKVLVYIEDVNDNSPVFTEN 1367 Query: 370 QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 V ++ + + A+D D + + Y + N F IT + G + + Sbjct: 1368 PIHVLISPKVLENKTIANVHASDVDLGLNGTVVYNLIKSNP--FFYITQEKGEVKLQMPL 1425 Query: 428 PLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 P +F VL V A+D G + T +V I+I + N Y A + E++ G Sbjct: 1426 PAEFSST---VLQVQASDLGIPPNTVTGLVIIDIQGLDKEIAFVHNF-YEAIILENSEAG 1481 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ--FVINPQTGAITTN--KLLDR 541 T V+ V A + ++ + EI + V D++ F +NP TG + +LLD Sbjct: 1482 TLVVTVKA----------LYHNPNDEIIHYTVFSGDKKGAFNLNPITGDLMVKEPRLLDF 1531 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 ET++ + L ++A + T + + D NDN PVF Q Y + + E T V Sbjct: 1532 ETVNKFNLIISAESSQYTTYCRVT---VFIQDDNDNAPVFDQLDYISFVSEGQPFNTFVI 1588 Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 QV A D D G+NG+I Y + E +FV+D G++ TN LDRE +++ L A D Sbjct: 1589 QVFAADGDSGINGQIDYSI-ISGNENNAFVLDSRHGILSTNVILDREIKSSYRLTVQATD 1647 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 G+P SST +V + I DIND+ P T I+E++ G +IG I A+D D P+ Sbjct: 1648 RGSPSCSSTSVVTVLILDINDNAPTI-PPMNTVLIAEDAAPGYSIGSISANDVDLRPDLS 1706 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVIRAASPPLWNDVRV 780 ++ + G+ F+++ G ++T+ + LDYE ++ L I+A+ + + Sbjct: 1707 YTFT-ENGNPGLKFAIDRYSG-----IITLTESLDYEE-SSQHCLRIQASDSVYHTEAEL 1759 Query: 781 EILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNAN 838 I V DVNDN PV +++ + D+++ + Y+I+S Sbjct: 1760 IIKVLDVNDNPPVFTQNIYKVALPELTESNTFITTVSATDQDSEIYGPITYKIISPLKG- 1818 Query: 839 LILLNETTGSM 849 ++N T+G + Sbjct: 1819 -FVINTTSGKL 1828 Score = 275 bits (675), Expect = 1e-71 Identities = 260/903 (28%), Positives = 422/903 (46%), Gaps = 76/903 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I VLD ND+ P F QY VRE G+ VL L+A+D D G N E+ Y++ DT Sbjct: 1246 RITVLDENDNPPTFPKSQYRTLVREDLKIGSAVLKLQASDADEGLNKEIMYSL---IDDT 1302 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 Q F ++ +G ++T +LDRE +Y V A+D + + + Sbjct: 1303 -----------------QGAFTVNRTTGNIVTIRTLDREVKHQYVFRVVASDCS--LRNP 1343 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S+T + V I D NDN P F+E V + V +N IA + A+D D+G N + Y Sbjct: 1344 KSATVKVLVYIEDVNDNSPVFTENPIHVLISP--KVLENKTIANVHASDVDLGLNGTVVY 1401 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 +I N F I G+V L L E S L ++A D G P + T ++I+I+ Sbjct: 1402 NLIKSNPF--FYITQEKGEVKLQMPLPAE-FSSTVLQVQASDLGIPPNTVTGLVIIDIQG 1458 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL-P 308 + D F + ++ + EN G +V V+A + + + YT+ D G +L P Sbjct: 1459 L-DKEIAFVHNFYEAIILENSEAGTLVVTVKALYHNPN-DEIIHYTVFSGDKKGAFNLNP 1516 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 IT D V LD ET K+ L+++A + F Sbjct: 1517 ITGDLM---VKEPRLLDFETVNKFNLIISAESS---QYTTYCRVTVFIQDDNDNAPVFDQ 1570 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 Y ++E +P T V+ + A D D + ++ Y I GN F + S++G +++ Sbjct: 1571 LDYISFVSEGQPFNTFVIQVFAADGDSGINGQIDYSIISGNENNAFVLDSRHG--ILSTN 1628 Query: 427 QPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 LD + + Y LTV ATD G S T++V + I D N+ AP T + EDA Sbjct: 1629 VILDREIKSSYRLTVQATDRGSPSCSSTSVVTVLILDINDNAPTIPPMN-TVLIAEDAAP 1687 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 G ++ +SA D D+ + T++ E N + +F I+ +G IT + LD E Sbjct: 1688 GYSIGSISANDVDLRPDLSYTFT---ENGNPGL-----KFAIDRYSGIITLTESLDYEES 1739 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 S + L + A D + ++ I V+DVNDN PVF Q +Y + E T ++ V Sbjct: 1740 SQHCLRIQASDSVYHT---EAELIIKVLDVNDNPPVFTQNIYKVALPELTESNTFITTVS 1796 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR---TNKALDRESVATH-DLKAVAI 660 ATD D + G I Y++ + FVI+ SG +R T+ L +E+ +T + VA+ Sbjct: 1797 ATDQDSEIYGPITYKIISPLK---GFVINTTSGKLRSVYTDMPLGKENKSTEIQILIVAM 1853 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP-N 719 D G+PP +ST ++ + I D+N+ P F D +SE++ +G T+ + A D D P N Sbjct: 1854 DNGSPPLTSTAMLSVTILDVNNYAPTFSEDIYYVNVSEDALVGDTVLTLTAMDLDWSPKN 1913 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDK------AELVTMVDLDYE--SPRKKYELVIRAAS 771 A++ +SI GG+ N F LE+ + +L+ LD+E S + V Sbjct: 1914 ALIDFSIIGGNAHNLFYLESSEVLSHIPFIVTGKLIINQPLDFEVASAHRLDIFVSNQGF 1973 Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPAYDADVTDK--LQ 828 PPL + + I + D NDN P+ + + + ++ +P+ + A D+D + + Sbjct: 1974 PPLNSSATIIINILDSNDNPPLFSNSEYHVS-VREHYPLKSTIIIISATDSDTGENADIT 2032 Query: 829 YRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIK--AMMQLSVRL 886 Y I+SGN+ N+ ++ G++TL L+ ++ + DG + A LS+ + Sbjct: 2033 YSIVSGNDENVFTIDAQNGTVTLVQPLDYEETMKYSLTLQARDGHGSKRNVAFALLSITV 2092 Query: 887 ITE 889 + E Sbjct: 2093 LDE 2095 Score = 268 bits (656), Expect = 2e-69 Identities = 243/846 (28%), Positives = 391/846 (46%), Gaps = 82/846 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND+SPVF + T+ + A+D D+G N V Y L+ + Sbjct: 1352 VYIEDVNDNSPVFTENPIHVLISPKVLENKTIANVHASDVDLGLNGTVVYN--LIKS--- 1406 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVL-VKATDQASPVSDR 129 NP F I G + + L E + TVL V+A+D P + Sbjct: 1407 NP----------------FFYITQEKGEVKLQMPLPAEFSS--TVLQVQASDLGIPPN-- 1446 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + T + ++I D F Y + E+ ++ +KA + + I Y Sbjct: 1447 -TVTGLVIIDI-QGLDKEIAFVHNFYEAIILENSEA--GTLVVTVKALYHNPN-DEIIHY 1501 Query: 190 AIIGGNTQMQFSIDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 + G+ + F+++ ++GD+ + + LD+E V + L+I A+ S + ++ + I Sbjct: 1502 TVFSGDKKGAFNLNPITGDLMVKEPRLLDFETVNKFNLIISAE---SSQYTTYCRVTVFI 1558 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 +D NDNAP F + VSE P +++V A D D G+N ++ Y++ +GN + Sbjct: 1559 QDDNDNAPVFDQLDYISFVSEGQPFNTFVIQVFAADGDSGINGQIDYSII----SGNENN 1614 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 +D R G + T+ LDRE ++ Y+L V ATD G P S+T+ + Sbjct: 1615 AFVLDSRHGILSTNVILDREIKSSYRLTVQATDRGSPSCSSTSVVTVLILDINDNAPT-I 1673 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT-GGNTRGRFSITSQNGRGLITVA 426 P V +AED PG + +++A D D L Y T GN +F+I +G +IT+ Sbjct: 1674 PPMNTVLIAEDAAPGYSIGSISANDVDLRPDLSYTFTENGNPGLKFAIDRYSG--IITLT 1731 Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 + LD+++ ++ L + A+DS ++ ++ I + D N+ PVF Y ++ E T Sbjct: 1732 ESLDYEESSQHCLRIQASDSVYHTEAELI-IKVLDVNDNPPVFTQNIYKVALPELTESNT 1790 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG---AITTNKLLDRET 543 + VSATD D I ITY + S + FVIN +G ++ T+ L +E Sbjct: 1791 FITTVSATDQDSEIYGPITYKIISPLKG---------FVINTTSGKLRSVYTDMPLGKEN 1841 Query: 544 MSGYL-LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 S + + + A D G P L+ T + ++++DVN+ P F + +Y N+ EDALVG +V Sbjct: 1842 KSTEIQILIVAMDNGSPPLTSTAMLSVTILDVNNYAPTFSEDIYYVNVSEDALVGDTVLT 1901 Query: 603 VGATDADVG----------LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652 + A D D + G H + E S + +G + N+ LD E + Sbjct: 1902 LTAMDLDWSPKNALIDFSIIGGNAHNLFYLESSEVLSHIPFIVTGKLIINQPLDFEVASA 1961 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 H L + G PP +S+ + I I D ND+PP+F + + E+ P+ +TI I A Sbjct: 1962 HRLDIFVSNQGFPPLNSSATIIINILDSNDNPPLFSNSEYHVSVREHYPLKSTIIIISAT 2021 Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVIRA-- 769 D D G NA + YSI G+D N F+++ + G+ VT+V LDYE KY L ++A Sbjct: 2022 DSDTGENADITYSIVSGNDENVFTIDAQNGT-----VTLVQPLDYEE-TMKYSLTLQARD 2075 Query: 770 --ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKL 827 S + I V D ND AP FQ N + P F V + +A D Sbjct: 2076 GHGSKRNVAFALLSITVLDENDFAPKFL-FQSQSCNIYENVPF--FSPVCSVNAIDLDSG 2132 Query: 828 QYRILS 833 QY ILS Sbjct: 2133 QYGILS 2138 Score = 245 bits (600), Expect = 1e-62 Identities = 249/922 (27%), Positives = 413/922 (44%), Gaps = 90/922 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++++ D ND++PVFE Y S+ GT +L + A D+D G +V Y EL++ + Sbjct: 76 RVDIEDINDNAPVFEPSTYVTSISSHTQPGTEILNVMAIDRDEGLFGDVTY--ELLSGEH 133 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 +F ID +G + + L + + ++ V A D+ S Sbjct: 134 -----------------SSLFTIDSSTGIIYLISVLSHLEDSWVSLSVAARDKGGLTS-- 174 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + AT+ +NI+ F + YT + ED V + +KA + + + + Y Sbjct: 175 -AVNATVTMNILKTATAPAIFEKSRYTFVIAED--VPKGSAVGTVKARE-PLNSLEPVSY 230 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 II GN F+I + G + K LD+E + L +++Q G S S ++TQ+ + I D Sbjct: 231 RIISGNVHQMFTIHTQFGIIRTQKELDFESLPLVVLTVQSQLGSS-SVFSSTQVNVTITD 289 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 NDN P F + + SV +N G +I QA D D G N +++Y++ + N DL I Sbjct: 290 ANDNPPVFSSENERISVHQNTSPGTAIYIAQATDLDSGFNGQISYSIASE----NQDLFI 345 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT-XXXXXXXXXXXXXXFMP 368 ID G +Y + L + ++ LL+ A D G P S+ T F Sbjct: 346 -IDSTFGVLYLNATL--SSVREHVLLILAEDYGHPVISSLLTLTIIVEQNKQSNTLSFFN 402 Query: 369 GQYEVELAEDEPPGTPVVTL---TATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV 425 + E++E P + ++ + T + + Y ++ F I G I + Sbjct: 403 LVHRTEISETLPINSHILQVKAYTRNTQSTSSEIMYSLSPTIDSAPFRI--HQSTGWIFL 460 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSD----TAMVQINITDANNYAPVFENAPYTASVFED 481 + +D+++ + + L V AT SG R D TA + + I D N+ +P F++A + +V E Sbjct: 461 RRSVDYEKSKTHNLKVVAT-SGDREDQQTATASIIVKILDENDNSPSFDHATHFFTVNES 519 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 + + A D D G N Q++Y L SE +N F+I+ +TG I LDR Sbjct: 520 PVPHGVIGSIQAFDRDSGNNGQLSYFLLSEGNN---------FLISSKTGEIINCASLDR 570 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ-----QLYTANIMEDALV 596 E + + L V D G P + TT V I V D+NDN+P F Q QL+ +ME Sbjct: 571 ERKAHHELNVLVTDNGTPRRNATTTVYIIVADLNDNKPYFPQLASGKQLH-VKVMEGQAE 629 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 V+ V A D D G NG + Y D G FVI+ ++G I T KAL + + L Sbjct: 630 PMLVATVYAKDPDAGNNGTVVY-FFASDESFGQFVINASTGEIWTTKALTAKLRPQYGLT 688 Query: 657 AVAIDGGTPPQSSTVIVHIKI---EDINDSPPVFE--------SDCLTFYISENSPIGTT 705 A D GTPP +V+I+I ++ PP S T + EN+ Sbjct: 689 VTASDQGTPPLVEHTVVNIEITITAEVLQHPPKVSFKEKTKTVSKIKTMKVPENTYPTQK 748 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765 IG + +H+ ++ +HY + ++ F +++ G ++ LD+E+ Y L Sbjct: 749 IGSVISHEEAFLLSSKMHYRLANEENKGHFVVDSLTG----DVYVSRHLDFET-ISYYGL 803 Query: 766 -----VIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAY 819 I SPP + V + I + D ND+ P+ D I+ +D PVG A Sbjct: 804 SIDIQEIDKISPPNLS-VFLTIYIEDTNDHRPLFPDHIIVLGVDED-VPVGTLLYTFKAN 861 Query: 820 DAD---VTDKLQYRI-LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE 875 D D K++Y + G N ++E G++T + +L+ + + + V+ TD Sbjct: 862 DKDGSLENSKIRYSLNTHGTGENPFFIHEWEGALTTANELDREMAESFVLTVTATDQAAN 921 Query: 876 I--KAMMQLSVRLITEEMLLNS 895 I + + VR++ +++ NS Sbjct: 922 ISHRRCTSVIVRIVIQDINDNS 943 Score = 245 bits (600), Expect = 1e-62 Identities = 243/875 (27%), Positives = 396/875 (45%), Gaps = 73/875 (8%) Query: 86 VQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145 V +F I + G + T+ LD E + LV T Q+ S + S+ ++V I D ND Sbjct: 237 VHQMFTIHTQFGIIRTQKELDFESLP----LVVLTVQSQLGSSSVFSSTQVNVTITDAND 292 Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205 N P FS + +SV ++ S IA+ ATD D G N I Y+I N + F IDS Sbjct: 293 NPPVFSSENERISVHQNTSPGTAIYIAQ--ATDLDSGFNGQISYSIASENQDL-FIIDST 349 Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI-RDVNDNAPRFYTSLFQE 264 G + L TL VR + L+I A+D G P S+ L I + ++ N F+ + + Sbjct: 350 FGVLYLNATLS--SVREHVLLILAEDYGHPVISSLLTLTIIVEQNKQSNTLSFFNLVHRT 407 Query: 265 SVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYTGNVD-LPITIDPRSGWVYTSG 322 +SE +PI I++V+AY + + ++E+ Y+++ +D P I +GW++ Sbjct: 408 EISETLPINSHILQVKAYTRNTQSTSSEIMYSLSP-----TIDSAPFRIHQSTGWIFLRR 462 Query: 323 QLDRETQAKYQLLVTATDGG-DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381 +D E + L V AT G + ++ATA+ F + + E P Sbjct: 463 SVDYEKSKTHNLKVVATSGDREDQQTATASIIVKILDENDNSPSFDHATHFFTVNESPVP 522 Query: 382 GTPVVTLTATDADEDNR---LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYV 438 + ++ A D D N ++ ++ GN F I+S+ G +I A LD +++ + Sbjct: 523 HGVIGSIQAFDRDSGNNGQLSYFLLSEGNN---FLISSKTGE-IINCAS-LDRERKAHHE 577 Query: 439 LTVSATDSGG--RSDTAMVQINITDANNYAPVF----ENAPYTASVFEDAPIGTTVLVVS 492 L V TD+G R+ T V I + D N+ P F V E V V Sbjct: 578 LNVLVTDNGTPRRNATTTVYIIVADLNDNKPYFPQLASGKQLHVKVMEGQAEPMLVATVY 637 Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552 A D D G N + Y +S+ S QFVIN TG I T K L + Y LTVT Sbjct: 638 AKDPDAGNNGTVVYFFASDESFG-------QFVINASTGEIWTTKALTAKLRPQYGLTVT 690 Query: 553 ARDGGVPSLSDTTDVEISVV---DVNDNEPV--FKQQ------LYTANIMEDALVGTSVS 601 A D G P L + T V I + +V + P FK++ + T + E+ + Sbjct: 691 ASDQGTPPLVEHTVVNIEITITAEVLQHPPKVSFKEKTKTVSKIKTMKVPENTYPTQKIG 750 Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA--VA 659 V + + L+ ++HY L + +G FV+D +G + ++ LD E+++ + L Sbjct: 751 SVISHEEAFLLSSKMHYRL-ANEENKGHFVVDSLTGDVYVSRHLDFETISYYGLSIDIQE 809 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG-P 718 ID +PP S V + I IED ND P+F + + E+ P+GT + +A+D D Sbjct: 810 IDKISPPNLS-VFLTIYIEDTNDHRPLFPDHIIVLGVDEDVPVGTLLYTFKANDKDGSLE 868 Query: 719 NAVVHYSIK-GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA------S 771 N+ + YS+ G N F + +G+ L T +LD E + + L + A S Sbjct: 869 NSKIRYSLNTHGTGENPFFIHEWEGA----LTTANELDREM-AESFVLTVTATDQAANIS 923 Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQY 829 V V I++ D+NDN+P + + + +D R+ A D D K+ + Sbjct: 924 HRRCTSVIVRIVIQDINDNSPQVLSLPVA-SVMEDAQIGSLVHRIVAKDPDEGRNGKIGF 982 Query: 830 RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV-SVTDGVNEIKAMMQLSVRLIT 888 I GN + LL+ETTG +TL +++ V + + ++ DG+ + L++ LI Sbjct: 983 HIKEGNAQQVFLLDETTGWLTLHSEIDREVQDHYILTILALDDGIPSLSVTQTLTISLID 1042 Query: 889 EEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAI 923 + T L + + P G ++ +AA+ Sbjct: 1043 VNDKTPTFTQGLYEAAVPENQDP--GLYVIKVAAV 1075 Score = 235 bits (576), Expect = 1e-59 Identities = 190/633 (30%), Positives = 294/633 (46%), Gaps = 39/633 (6%) Query: 173 KIKATDADVGANSAIRYAIIGG--NTQ--MQFSIDSLSGDVSLVKTLDYEQ-VRSYRLVI 227 K+KATDAD G I Y++ G NT+ F ID SG + + +D E SY L++ Sbjct: 2 KVKATDADSGPFGQIHYSVYDGFHNTKESQSFRIDPDSGRICVSNDIDKESGPTSYDLLV 61 Query: 228 RAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG 287 +A+D G S + ++I D+NDNAP F S + S+S + G I+ V A D DEG Sbjct: 62 KAEDEGGLSAQAFVR--VDIEDINDNAPVFEPSTYVTSISSHTQPGTEILNVMAIDRDEG 119 Query: 288 VNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRS 347 + ++TY + +++ TID +G +Y L + L V A D G + Sbjct: 120 LFGDVTYELLSGEHSS----LFTIDSSTGIIYLISVLSHLEDSWVSLSVAARDKGGLTSA 175 Query: 348 ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD-ADEDNRLHYEITGG 406 AT F +Y +AED P G+ V T+ A + + + Y I G Sbjct: 176 VNATVTMNILKTATAPAIFEKSRYTFVIAEDVPKGSAVGTVKAREPLNSLEPVSYRIISG 235 Query: 407 NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV-SATDSGGRSDTAMVQINITDANNY 465 N F+I +Q G+I + LDF+ VLTV S S + V + ITDAN+ Sbjct: 236 NVHQMFTIHTQ--FGIIRTQKELDFESLPLVVLTVQSQLGSSSVFSSTQVNVTITDANDN 293 Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525 PVF + SV ++ GT + + ATD D G N QI+YS++SE + F+ Sbjct: 294 PPVFSSENERISVHQNTSPGTAIYIAQATDLDSGFNGQISYSIASE--------NQDLFI 345 Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN--DNEPVFKQ 583 I+ G + N L ++ ++L + A D G P +S + I +V+ N N F Sbjct: 346 IDSTFGVLYLNATL--SSVREHVLLILAEDYGHPVISSLLTLTI-IVEQNKQSNTLSFFN 402 Query: 584 QLYTANIMEDALVGTSVSQVGA-TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642 ++ I E + + + QV A T + I Y L P + F I ++G I Sbjct: 403 LVHRTEISETLPINSHILQVKAYTRNTQSTSSEIMYSLSP-TIDSAPFRIHQSTGWIFLR 461 Query: 643 KALDRESVATHDLKAVAIDGG-TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701 +++D E TH+LK VA G Q++T + +KI D ND+ P F+ F ++E+ Sbjct: 462 RSVDYEKSKTHNLKVVATSGDREDQQTATASIIVKILDENDNSPSFDHATHFFTVNESPV 521 Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPR 760 IG I+A D D G N + Y + + N+F + ++ G E++ LD E Sbjct: 522 PHGVIGSIQAFDRDSGNNGQLSYFLL--SEGNNFLISSKTG----EIINCASLDRERKAH 575 Query: 761 KKYELVIRAASPPLWN-DVRVEILVTDVNDNAP 792 + +++ P N V I+V D+NDN P Sbjct: 576 HELNVLVTDNGTPRRNATTTVYIIVADLNDNKP 608 Score = 235 bits (575), Expect = 1e-59 Identities = 240/891 (26%), Positives = 388/891 (43%), Gaps = 74/891 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND+ PVF + SV + S GT + +ATD D G N ++ Y+I Sbjct: 285 VTITDANDNPPVFSSENERISVHQNTSPGTAIYIAQATDLDSGFNGQISYSI-------- 336 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 QD+F ID G L A+L V + +L+ A D PV + Sbjct: 337 ------------ASENQDLFIIDSTFGVLYLNATLS--SVREHVLLILAEDYGHPV---I 379 Query: 131 SSTATIHVNIIDDN--DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKA-TDADVGANSAI 187 SS T+ + I++ N N F + + E + + N I ++KA T +S I Sbjct: 380 SSLLTLTI-IVEQNKQSNTLSFFNLVHRTEISETLPI--NSHILQVKAYTRNTQSTSSEI 436 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT-QLLIN 246 Y++ F I +G + L +++DYE+ +++ L + A G + T +++ Sbjct: 437 MYSLSPTIDSAPFRIHQSTGWIFLRRSVDYEKSKTHNLKVVATSGDREDQQTATASIIVK 496 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIV-RVQAYDADEGVNAELTYTMTDKDYTGNV 305 I D NDN+P F + +V+E+ P+ + ++ +QA+D D G N +L+Y + + GN Sbjct: 497 ILDENDNSPSFDHATHFFTVNES-PVPHGVIGSIQAFDRDSGNNGQLSYFLLSE---GNN 552 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 L I ++G + LDRE +A ++L V TD G P R+AT T Sbjct: 553 FL---ISSKTGEIINCASLDRERKAHHELNVLVTDNGTPRRNATTTVYIIVADLNDNKPY 609 Query: 366 FMP----GQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNG 419 F Q V++ E + V T+ A D D N + Y + G+F I + G Sbjct: 610 FPQLASGKQLHVKVMEGQAEPMLVATVYAKDPDAGNNGTVVYFFASDESFGQFVINASTG 669 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479 I + L K +Y LTV+A+D G +NI + A V ++ P + Sbjct: 670 E--IWTTKALTAKLRPQYGLTVTASDQGTPPLVEHTVVNI-EITITAEVLQHPPKVSFKE 726 Query: 480 EDAPIGT--TVLVVSATDSDVGINAQITYS----LSSEISNEAVAHHDQ-QFVINPQTGA 532 + + T+ V T I + I++ LSS++ ++ FV++ TG Sbjct: 727 KTKTVSKIKTMKVPENTYPTQKIGSVISHEEAFLLSSKMHYRLANEENKGHFVVDSLTGD 786 Query: 533 ITTNKLLDRETMSGYLLTVTARDG---GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589 + ++ LD ET+S Y L++ ++ P+LS + I + D ND+ P+F + Sbjct: 787 VYVSRHLDFETISYYGLSIDIQEIDKISPPNLS--VFLTIYIEDTNDHRPLFPDHIIVLG 844 Query: 590 IMEDALVGTSVSQVGATDADVGL-NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648 + ED VGT + A D D L N +I Y L+ E F I G + T LDRE Sbjct: 845 VDEDVPVGTLLYTFKANDKDGSLENSKIRYSLNTHGTGENPFFIHEWEGALTTANELDRE 904 Query: 649 SVATHDLKAVAIDGG---TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 + L A D + + ++VIV I I+DIND+ P S + + E++ IG+ Sbjct: 905 MAESFVLTVTATDQAANISHRRCTSVIVRIVIQDINDNSPQVLSLPVAS-VMEDAQIGSL 963 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765 + I A DPDEG N + + IK G+ F L+ G L + +D + + L Sbjct: 964 VHRIVAKDPDEGRNGKIGFHIKEGNAQQVFLLDETTGW--LTLHSEIDREVQDHYILTIL 1021 Query: 766 VIRAASPPLWNDVRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPAYDADV 823 + P L + I + DVND P ++ +D P +V A D D+ Sbjct: 1022 ALDDGIPSLSVTQTLTISLIDVNDKTPTFTQGLYEAAVPENQD--PGLYVIKVAAVDYDL 1079 Query: 824 TDK--LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 + L Y IL G +N TG + + + +EV V DG Sbjct: 1080 GNNSVLTYEILPGPAYGHFRINPETGELVTTTVFDREQQDRFIIEVLVKDG 1130 Score = 196 bits (478), Expect = 7e-48 Identities = 206/796 (25%), Positives = 339/796 (42%), Gaps = 63/796 (7%) Query: 90 FRIDGRSGALLTRASLDREK-VARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 FRID SG + +D+E Y +LVKA D+ LS+ A + V+I D NDN P Sbjct: 33 FRIDPDSGRICVSNDIDKESGPTSYDLLVKAEDEGG-----LSAQAFVRVDIEDINDNAP 87 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 F TY S+ I + A D D G + Y ++ G F+IDS +G Sbjct: 88 VFEPSTYVTSISSHTQ--PGTEILNVMAIDRDEGLFGDVTYELLSGEHSSLFTIDSSTGI 145 Query: 209 VSLVKTLDYEQVRSYRLVIRAQD-GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 + L+ L + + L + A+D GG S N T + +NI F S + ++ Sbjct: 146 IYLISVLSHLEDSWVSLSVAARDKGGLTSAVNAT-VTMNILKTATAPAIFEKSRYTFVIA 204 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 E+VP G ++ V+A + + ++Y + +GNV TI + G + T +LD E Sbjct: 205 EDVPKGSAVGTVKAREPLNSLEP-VSYRII----SGNVHQMFTIHTQFGIIRTQKELDFE 259 Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387 + L V + G S+T F + + ++ PGT + Sbjct: 260 SLPLVVLTVQSQLGSSSVFSSTQVNVTITDANDNPPV-FSSENERISVHQNTSPGTAIYI 318 Query: 388 LTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445 ATD D + ++ Y I N + F I S G + R +VL + A D Sbjct: 319 AQATDLDSGFNGQISYSIASEN-QDLFIIDSTFGVLYLNAT----LSSVREHVLLILAED 373 Query: 446 SGGRSDTAMVQINI-TDANNYAPV--FENAPYTASVFEDAPIGTTVLVVSA-TDSDVGIN 501 G ++++ + I + N + F N + + E PI + +L V A T + + Sbjct: 374 YGHPVISSLLTLTIIVEQNKQSNTLSFFNLVHRTEISETLPINSHILQVKAYTRNTQSTS 433 Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG-VPS 560 ++I YSLS I + F I+ TG I + +D E + L V A G Sbjct: 434 SEIMYSLSPTIDSAP-------FRIHQSTGWIFLRRSVDYEKSKTHNLKVVATSGDREDQ 486 Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620 + T + + ++D NDN P F + + E + + + A D D G NG++ Y L Sbjct: 487 QTATASIIVKILDENDNSPSFDHATHFFTVNESPVPHGVIGSIQAFDRDSGNNGQLSYFL 546 Query: 621 DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680 E +F+I +G I +LDRE A H+L + D GTP +++T V+I + D+ Sbjct: 547 LS---EGNNFLISSKTGEIINCASLDRERKAHHELNVLVTDNGTPRRNATTTVYIIVADL 603 Query: 681 NDSPPVF----ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736 ND+ P F L + E + + A DPD G N V Y + F Sbjct: 604 NDNKPYFPQLASGKQLHVKVMEGQAEPMLVATVYAKDPDAGNNGTVVYFFASDESFGQFV 663 Query: 737 LETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWND--VRVEILVT-DVNDN 790 + G E+ T L + R +Y L + A+ +PPL V +EI +T +V + Sbjct: 664 INASTG----EIWTTKALTAKL-RPQYGLTVTASDQGTPPLVEHTVVNIEITITAEVLQH 718 Query: 791 APVM--KDFQIIFNNYK------DCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLI 840 P + K+ + K + +P G V +++ ++ K+ YR+ + N Sbjct: 719 PPKVSFKEKTKTVSKIKTMKVPENTYPTQKIGSVISHEEAFLLSSKMHYRLANEENKGHF 778 Query: 841 LLNETTGSMTLSPQLN 856 +++ TG + +S L+ Sbjct: 779 VVDSLTGDVYVSRHLD 794 Score = 189 bits (460), Expect = 1e-45 Identities = 172/609 (28%), Positives = 273/609 (44%), Gaps = 39/609 (6%) Query: 277 VRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET-QAKYQLL 335 ++V+A DAD G ++ Y++ D + IDP SG + S +D+E+ Y LL Sbjct: 1 IKVKATDADSGPFGQIHYSVYDGFHNTKESQSFRIDPDSGRICVSNDIDKESGPTSYDLL 60 Query: 336 VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395 V A D G SA A F P Y ++ PGT ++ + A D DE Sbjct: 61 VKAEDEGG--LSAQAFVRVDIEDINDNAPVFEPSTYVTSISSHTQPGTEILNVMAIDRDE 118 Query: 396 D--NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSD-- 451 + YE+ G F+I S G+I + L ++ L+V+A D GG + Sbjct: 119 GLFGDVTYELLSGEHSSLFTIDSST--GIIYLISVLSHLEDSWVSLSVAARDKGGLTSAV 176 Query: 452 TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE 511 A V +NI +FE + YT + ED P G+ V V A + + ++Y + S Sbjct: 177 NATVTMNILKTATAPAIFEKSRYTFVIAEDVPKGSAVGTVKARE-PLNSLEPVSYRIIS- 234 Query: 512 ISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571 + Q F I+ Q G I T K LD E++ +LTV ++ G S+ +T V +++ Sbjct: 235 ------GNVHQMFTIHTQFGIIRTQKELDFESLPLVVLTVQSQLGS-SSVFSSTQVNVTI 287 Query: 572 VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631 D NDN PVF + ++ ++ GT++ ATD D G NG+I Y + ++++ F+ Sbjct: 288 TDANDNPPVFSSENERISVHQNTSPGTAIYIAQATDLDSGFNGQISYSIASENQD--LFI 345 Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV-FESD 690 ID GV+ N L SV H L +A D G P SS + + I +E S + F + Sbjct: 346 IDSTFGVLYLNATL--SSVREHVLLILAEDYGHPVISSLLTLTIIVEQNKQSNTLSFFNL 403 Query: 691 CLTFYISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV 749 ISE PI + I +++A+ + + ++ + YS+ DS F + G + Sbjct: 404 VHRTEISETLPINSHILQVKAYTRNTQSTSSEIMYSLSPTIDSAPFRIHQSTG----WIF 459 Query: 750 TMVDLDYESPRKKYELVIRAASPPLWND----VRVEILVTDVNDNAPVMKDFQIIFNNYK 805 +DYE K + L + A S + + + + D NDN+P F + Sbjct: 460 LRRSVDYEK-SKTHNLKVVATSGDREDQQTATASIIVKILDENDNSPSFDHATHFFTVNE 518 Query: 806 DCFPVGPFGRVPAYDADV--TDKLQYRILS-GNNANLILLNETTGSMTLSPQLNTNVPKL 862 P G G + A+D D +L Y +LS GNN L++ TG + L+ Sbjct: 519 SPVPHGVIGSIQAFDRDSGNNGQLSYFLLSEGNN---FLISSKTGEIINCASLDRERKAH 575 Query: 863 ATMEVSVTD 871 + V VTD Sbjct: 576 HELNVLVTD 584 Score = 148 bits (358), Expect = 3e-33 Identities = 140/518 (27%), Positives = 235/518 (45%), Gaps = 32/518 (6%) Query: 386 VTLTATDADED--NRLHYEITGG--NTRGRFSITSQNGRGLITVAQPLDFKQ-ERRYVLT 440 + + ATDAD ++HY + G NT+ S G I V+ +D + Y L Sbjct: 1 IKVKATDADSGPFGQIHYSVYDGFHNTKESQSFRIDPDSGRICVSNDIDKESGPTSYDLL 60 Query: 441 VSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 V A D GG S A V+++I D N+ APVFE + Y S+ GT +L V A D D G+ Sbjct: 61 VKAEDEGGLSAQAFVRVDIEDINDNAPVFEPSTYVTSISSHTQPGTEILNVMAIDRDEGL 120 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD-GGVP 559 +TY L S H F I+ TG I +L S L+V ARD GG+ Sbjct: 121 FGDVTYELLS-------GEHSSLFTIDSSTGIIYLISVLSHLEDSWVSLSVAARDKGGLT 173 Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619 S + T V ++++ +F++ YT I ED G++V V A + L + Y Sbjct: 174 SAVNAT-VTMNILKTATAPAIFEKSRYTFVIAEDVPKGSAVGTVKAREPLNSLE-PVSYR 231 Query: 620 LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679 + + + F I G+IRT K LD ES+ L + G + SST V++ I D Sbjct: 232 IISGNVHQ-MFTIHTQFGIIRTQKELDFESLPLVVLTVQSQLGSSSVFSSTQ-VNVTITD 289 Query: 680 INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLET 739 ND+PPVF S+ + +N+ GT I +A D D G N + YSI ++ + F +++ Sbjct: 290 ANDNPPVFSSENERISVHQNTSPGTAIYIAQATDLDSGFNGQISYSI-ASENQDLFIIDS 348 Query: 740 RQGSDKAELVTMVDLDYESPRKKYELVI-RAASPPLWNDVRVEILVTDVNDNAPVMKDFQ 798 G V ++ S R+ L++ P+ + + ++ + N + + F Sbjct: 349 TFG------VLYLNATLSSVREHVLLILAEDYGHPVISSLLTLTIIVEQNKQSNTLSFFN 402 Query: 799 IIF-NNYKDCFPVGP-FGRVPAYDAD---VTDKLQYRILSGNNANLILLNETTGSMTLSP 853 ++ + P+ +V AY + + ++ Y + ++ ++++TG + L Sbjct: 403 LVHRTEISETLPINSHILQVKAYTRNTQSTSSEIMYSLSPTIDSAPFRIHQSTGWIFLRR 462 Query: 854 QLNTNVPKLATMEVSVTDGVNEIK--AMMQLSVRLITE 889 ++ K ++V T G E + A + V+++ E Sbjct: 463 SVDYEKSKTHNLKVVATSGDREDQQTATASIIVKILDE 500 >UniRef50_A7SAP5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 4354 Score = 347 bits (852), Expect = 3e-93 Identities = 301/981 (30%), Positives = 456/981 (46%), Gaps = 86/981 (8%) Query: 11 INVLDCNDHSPVF--EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68 IN++D ND SP F + A V E + T V+++KA D D G T E+ Sbjct: 2558 INIIDVNDVSPAFLLAINTRNARVLENKPAPTKVISMKAIDDD-GSEPHRRVTYEMKD-- 2614 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 NP F+ID +G + T+ +LDRE +Y V V A D + S Sbjct: 2615 --NPN----------------FQIDASTGMITTKTTLDREVTPKYDVEVTAKDGVNKES- 2655 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 A +++ ++D ND P F+ K+Y +SV ED + + + I ATDADVG N+ I Sbjct: 2656 -----AILYITVVDQNDQPPVFAPKSYAISVPEDSPIGTS--VLDIYATDADVGENAKIT 2708 Query: 189 YAIIGGNTQMQFSI--DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 Y I G+ + +FSI + G++ + LD+E SY L + A DG S+T + + Sbjct: 2709 YFISKGDPEGKFSIVTSPVKGELVVNGKLDFETKSSYTLEVTATDG---KFSDTAVVTVT 2765 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD--KDYTGN 304 I+DVND P F + L++ + EN G +V V A D D + +++++ D KDY Sbjct: 2766 IQDVNDLPPVFSSPLYESRIQENTGPGAGVVMVTASDID---SPTISFSLDDRGKDYFQI 2822 Query: 305 VDLPITIDPRSGWVYT----SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 + + P + WV S QLDRE V A DG +A A Sbjct: 2823 TPIRAS-GPGNVWVGDIRTGSKQLDREESPVKVFTVIANDG---KHTAQAEIRVNLTDVN 2878 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-----DNRLHYEITGGNTRGRFSIT 415 F Y + E++P GT V+ + A D D+ + +L YE+T + +FSI Sbjct: 2879 DNAPRFPASPYIGYVEENKPSGTSVMYIQAVDDDDPLAGGNAKLSYELTD-SAGDKFSID 2937 Query: 416 SQNGRGLITVAQPLDFKQE-RRYVLTVSATDSGGRSDTAMVQ--INITDANNYAPVFENA 472 +G LI D +Q ++ + V ATD+G +A V I+++DAN++ P F Sbjct: 2938 PLSG--LIKTKVTFDREQTPNKFKVRVKATDAGNPRLSASVDGIIHVSDANDHKPKFTEK 2995 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 Y SV E+AP G +VL V+ATD DVG NA+ + + N+ A F I+P G Sbjct: 2996 FYRGSVAENAPPGYSVLRVTATDEDVGPNAEFEFVVVQ--GNDPHA-----FYIDPFNGT 3048 Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLS--DTTDVEISVVDVNDNEPVFKQQLYTANI 590 + + +LD E Y +T+T D G+P L +T V I ++D NDN P F ++Y A++ Sbjct: 3049 VLVSGILDYEKKKEYTITLTVADRGMPPLQGDETAYVVIEILDANDNAPEFIPKIYNASV 3108 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP-----ASGVIRTNKAL 645 +ED V V A D D G NG + +DP+ + +F I+P + G+IRT L Sbjct: 3109 LEDVGARQPVLTVTAVDKDSGPNGNFTFAIDPRSDPDDAFTIEPNPNNASIGIIRTRVPL 3168 Query: 646 DRESVATHDLKAVAID-GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 D+E + LK A D GG + V I + D+ND+ P F I E Sbjct: 3169 DQEKTPSFHLKVTATDAGGLQGEGE---VRINVIDVNDNGPWFVPPFFVGQIKEGVSARQ 3225 Query: 705 TIGEIRAHDPDE-GPNAVVHYSIKGGDDSNSFSLE-TRQGSDKAELVTMVDLDYE-SPRK 761 + +++A+DPD + V+ +SI G +F L+ ++ +L + D E +P Sbjct: 3226 FVTKLKAYDPDAFVKDQVITFSIYNGTVGENFKLDPVSVTNESVDLHSYGVFDREAAPVW 3285 Query: 762 K--YELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY 819 K E V P N V + V DVNDNAP II N Y F G G+ Sbjct: 3286 KIGIEAVDNVGPKPQKNFTYVYVDVLDVNDNAPKDGSLLIIVNAYDGNFTGGVIGKPYYQ 3345 Query: 820 DADVT-DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKA 878 D D D+ Y + S + + +NE G +T +P + L D + + + Sbjct: 3346 DDDFDGDENTYELNSQSPGSYFRVNEGNGDITAAPMIPMGEYNLKIRVTEKKDSPSTVTS 3405 Query: 879 MMQLSVRLITEEMLLNSITVRLNDM-TAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQ 937 +++ VR I +E + N + V DM F+ F D LA+ + P +I IFSVQ Sbjct: 3406 SVRVLVRRIDKEAVDNGVAVEFTDMRKVGYFVGDYYKGFEDVLASTLGVPTGDIKIFSVQ 3465 Query: 938 DDTDVTGNILNVSFSARRPDA 958 D G + V F+ D+ Sbjct: 3466 KAHD-NGLAVVVFFTVAAKDS 3485 Score = 320 bits (785), Expect = 5e-85 Identities = 284/955 (29%), Positives = 447/955 (46%), Gaps = 84/955 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++NV+D NDH P F + Y SV +G++++T++A D DIG NA+V Y + Sbjct: 888 EVNVIDVNDHKPEFLQESYWLSVPSSTPAGSSLVTVQAEDMDIGTNAQVRYEL------- 940 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L E++ I + L T ++L RY +L++A+D A+ + Sbjct: 941 LRQENSERF-------------ILNDNNQLSTASTLTPN--VRYQLLIRASDSAT--RNP 983 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S+ ++V++ +++ F + +Y ++ ED S N ++ KAT + G++S I Y Sbjct: 984 SSAQVPVYVSVYSPSESPIVFDKSSYNQNLPEDSSA--NTLVFTAKATRS--GSSSGITY 1039 Query: 190 AIIGGNTQM---QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ-DGGSPSRSNTTQLLI 245 ++GG Q+ FSI +G V L+K LD+E + + +RA+ GG+ ++ + Sbjct: 1040 ELVGGYKQIGEAMFSIKPDTGQVYLIKKLDFETKSYFPIAVRAKYSGGAIELASEVVAKV 1099 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQ---AYDADEGVNAELTYTMTDKDYT 302 I DVNDN PRF F ES V +S Q A DAD G E+TY + T Sbjct: 1100 TIVDVNDNGPRF---AFHESSKTVVIDSFSAKDTQLARALDADSGSLGEVTYGIDGGRST 1156 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPPRSATATXXXXXXXXXX 361 N LP I+ ++G ++ + ++ + Y ++V ATDG D + Sbjct: 1157 SN--LPFNINVKTGMIFATREILYTQGSSYIIIVVATDGATDGSQKIQKFTVNVQVLDTP 1214 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421 F Y + E G V T+ A + + L Y GN F + NG G Sbjct: 1215 RPPSFPQKTYSAPVTETAGVGDTVTTVRAVYSKPNAFLKYTFVSGNEDNTFCV---NGFG 1271 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 +I+VA+ LD ++ Y L + T G D V +N+TD N+ AP F +A Y S+ E Sbjct: 1272 IISVAKSLDREKVAGYTLGMRVT-LGQHVDDTTVYVNLTDINDDAPHFTSAIYRRSIKEG 1330 Query: 482 APIGTTVLV-VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 T +L V A D D G N +I YS+ S + + D+ F I+ TG ITT LD Sbjct: 1331 LAEDTEILPPVIAVDHDFGSNGKILYSILSGVHPD----WDKYFNIDSATGKITTKMTLD 1386 Query: 541 RETMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 ET + L + A D G P LS V+I V+D NDN PVF Y A I A+ GTS Sbjct: 1387 YETHKSHTLFIRAEDNGSPKRLSGIAQVDIDVIDRNDNSPVFAAAFYRAKISLGAVKGTS 1446 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 V QV ATD D G NG+I Y + + EE +F I+ GVI +K+L + LK A Sbjct: 1447 VLQVHATDLDSGQNGQITYSI-IQGNEEEAFTIN-EQGVILVDKSLTTVAADKFSLKVEA 1504 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 D P+S +V V I + + D PP+F +T Y+ E P + ++A + Sbjct: 1505 RDKNASPRSGSVTVEINVY-LPDGPPMFVVSPVTVYVKEGVPANHRVAGVKA-----ATS 1558 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND-V 778 + Y++ G+++ F + GS L +LDYE R++YEL I A + V Sbjct: 1559 EALTYTLLSGNEAGMFRINPSTGS----LDATRELDYEE-RRRYELKIEARDTRDRSAMV 1613 Query: 779 RVEILVTDVNDNAPVMKDF---QIIFNNYKDCFPVG-----PFGRVPAYDADVTDKLQYR 830 + I+V ++NDN P D QI C P R+ A+D D D++ + Sbjct: 1614 ELIIIVVNINDNKPTFVDIVDGQIDRKAIGTCSPTDIAEGEVITRLGAFDRD-GDEITF- 1671 Query: 831 ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEE 890 I+ + +L + ++ G +T + ++PK+ V D E + VRL+ Sbjct: 1672 IVPDDVKDLFKI-DSRGVVTAKKPIE-DLPKIYPFNVKALDN-GEPPQETDVKVRLVFVH 1728 Query: 891 MLLNSITVRLN---DMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDV 942 + VR+N D ++ + +F +G+ +++ K N FSV+ + DV Sbjct: 1729 YRPDQKHVRVNVREDTPTGSVIATVRRYFPNGIVSLLLPEKAN---FSVRANGDV 1780 Score = 281 bits (690), Expect = 1e-73 Identities = 262/890 (29%), Positives = 405/890 (45%), Gaps = 85/890 (9%) Query: 12 NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71 NV D N++ P F S+RE T + L ATD D G+N ++ Y+IE ++ TL Sbjct: 2237 NVADANNNVPQFT-NCGTVSIRENDPRDTKITQLTATDADRGQNGQITYSIEDASSQTL- 2294 Query: 72 PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV--SDR 129 F I+ R+G + + SLDRE Y ++KA D +S S+R Sbjct: 2295 ------------------FSIEPRTGVVRSLTSLDRENKDSYNAIIKAEDGSSKQDESER 2336 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L + +N+ D NDN P F Y SV S + I ++ATDAD G+N+ I+Y Sbjct: 2337 LLWYCYLTINVEDVNDNRPYFLAAKYFGSVFS--SAPNGSNILTVQATDADSGSNAKIKY 2394 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQD-----GGSPSRSNTT 241 A++ + F +DS SG + L E + L + A+D G P + Sbjct: 2395 ALLDSAGGL-FRLDS-SGILRTNTNPARLQLETGKKLLLEVSAKDVESIAGTQPGKPTKY 2452 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 I I N+ P+F ++ S++EN+ G ++ R+ A + AE++Y D + Sbjct: 2453 TTQIEILVSNEEPPKFSQQVYTASINENMETGSTVTRITATSS---TGAEISYENVDTNP 2509 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 + + D G++ T + D E Y + A D S Sbjct: 2510 RAKILFRVQPD---GYIITGDRPDYERGTTYNMQFAAKDKKTLLYSTVKVVINIIDVNDV 2566 Query: 362 XXXXFMP-GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG-NTRGRFSITSQNG 419 + + E++P T V+++ A D D+ + H +T F I + G Sbjct: 2567 SPAFLLAINTRNARVLENKPAPTKVISMKAID-DDGSEPHRRVTYEMKDNPNFQIDASTG 2625 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479 +IT LD + +Y + V+A D G ++A++ I + D N+ PVF Y SV Sbjct: 2626 --MITTKTTLDREVTPKYDVEVTAKD-GVNKESAILYITVVDQNDQPPVFAPKSYAISVP 2682 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 ED+PIGT+VL + ATD+DVG NA+ITY +S + V +P G + N L Sbjct: 2683 EDSPIGTSVLDIYATDADVGENAKITYFIS-----KGDPEGKFSIVTSPVKGELVVNGKL 2737 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 D ET S Y L VTA DG SDT V +++ DVND PVF LY + I E+ G Sbjct: 2738 DFETKSSYTLEVTATDG---KFSDTAVVTVTIQDVNDLPPVFSSPLYESRIQENTGPGAG 2794 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP--ASGV-------IRT-NKALDRES 649 V V A+D D + I + LD DR + F I P ASG IRT +K LDRE Sbjct: 2795 VVMVTASDID---SPTISFSLD--DRGKDYFQITPIRASGPGNVWVGDIRTGSKQLDREE 2849 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 +A DG Q+ + + + D+ND+ P F + Y+ EN P GT++ I Sbjct: 2850 SPVKVFTVIANDGKHTAQAE---IRVNLTDVNDNAPRFPASPYIGYVEENKPSGTSVMYI 2906 Query: 710 RAHDPDE---GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV 766 +A D D+ G NA + Y + + FS++ G K T V D E K+++ Sbjct: 2907 QAVDDDDPLAGGNAKLSYELT-DSAGDKFSIDPLSGLIK----TKVTFDREQTPNKFKVR 2961 Query: 767 IR---AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV 823 ++ A +P L V I V+D ND+ P + + ++ P RV A D DV Sbjct: 2962 VKATDAGNPRLSASVDGIIHVSDANDHKPKFTEKFYRGSVAENAPPGYSVLRVTATDEDV 3021 Query: 824 --TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + ++ ++ GN+ + ++ G++ +S L+ K T+ ++V D Sbjct: 3022 GPNAEFEFVVVQGNDPHAFYIDPFNGTVLVSGILDYEKKKEYTITLTVAD 3071 Score = 243 bits (594), Expect = 6e-62 Identities = 251/909 (27%), Positives = 402/909 (44%), Gaps = 92/909 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ VLD ND+ P++ ++ A V + +G V L+A D+D G + V Y ++ + D Sbjct: 1812 EVVVLDVNDNRPIWMERERLARVNTNSRAGAQVYQLEARDEDDGSSGLVGYQLKSPSNDA 1871 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 Q F I+ ++ + SL K RY + V A D P R Sbjct: 1872 KRKR---------RSPPQHPFTINPKTRQMEVAGSL---KDQRYDLDVFAFDYGIP---R 1916 Query: 130 LSS-TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 L+S T T++V+ P+FS+ +Y V ED ++ I A + + + Sbjct: 1917 LTSDTITLNVDGSAAGQLPPRFSKVSYHFMVSEDAKYLS--LVGIILARSI---SGARLD 1971 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGGSPSRSNTTQLLINI 247 Y I+ GN +F I G + L LD+E+ ++ Y L ++A + +T + I++ Sbjct: 1972 YKIVSGNVGDKF-IAMGDGRILLNSLLDFERDQTQYNLKVKATEQIPDGLDSTVDVKIDV 2030 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE-----LTYTMTDKDYT 302 + ND+ P F L+ + E+ +G + V A D D + LTY++ Sbjct: 2031 INANDHFPYFDQQLYSVQIPESTAVGVLVQEVTAKDCDCLSSCTCSPGFLTYSIEPSKEQ 2090 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 G IDP +G + S LD E Q + L V ATD G Sbjct: 2091 GG---KFYIDPATGKISVSVALDYEDQRYHLLKVYATDKGKKSFQGLCFVNVTLTNVNDN 2147 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422 F+ YE +AE G + + A DAD D + Y GG +FS+ G+ Sbjct: 2148 RPTFLKSAYEFRVAEGAATGESLAIVVAVDADGD-AVTYSKAGGAL--QFSV--DQSTGV 2202 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 IT+ LD + +Y L V A DSGG + T V N+ DANN P F N T S+ E+ Sbjct: 2203 ITLNSALD-PNKNQYTLQVMAKDSGGLTSTVSVTFNVADANNNVPQFTNCG-TVSIREND 2260 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 P T + ++ATD+D G N QITYS+ + S++ + F I P+TG + + LDRE Sbjct: 2261 PRDTKITQLTATDADRGQNGQITYSI-EDASSQTL------FSIEPRTGVVRSLTSLDRE 2313 Query: 543 TMSGYLLTVTARDGGVPSLSDTTD-------VEISVVDVNDNEPVFKQQLYTANIMEDAL 595 Y + A DG S D ++ + I+V DVNDN P F Y ++ A Sbjct: 2314 NKDSYNAIIKAEDGS--SKQDESERLLWYCYLTINVEDVNDNRPYFLAAKYFGSVFSSAP 2371 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN---KALDRES--- 649 G+++ V ATDAD G N +I Y L D G F +D +SG++RTN L E+ Sbjct: 2372 NGSNILTVQATDADSGSNAKIKYAL--LDSAGGLFRLD-SSGILRTNTNPARLQLETGKK 2428 Query: 650 ----VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 V+ D++++A G P + + I+I N+ PP F T I+EN G+T Sbjct: 2429 LLLEVSAKDVESIA--GTQPGKPTKYTTQIEILVSNEEPPKFSQQVYTASINENMETGST 2486 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPRKKYE 764 + I A A + Y D+N + + ++T DYE + Sbjct: 2487 VTRITA---TSSTGAEISYE---NVDTNPRAKILFRVQPDGYIITGDRPDYERGTTYNMQ 2540 Query: 765 LVIRAASPPLWNDVRVEILVTDVNDNAPVM------KDFQIIFNNYKDCFPVGPFGRVPA 818 + L++ V+V I + DVND +P ++ +++ N + + A Sbjct: 2541 FAAKDKKTLLYSTVKVVINIIDVNDVSPAFLLAINTRNARVLENKPAPTKVIS----MKA 2596 Query: 819 YDADVTD---KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE 875 D D ++ ++ Y + N ++ +TG +T L+ V +EV+ DGVN+ Sbjct: 2597 IDDDGSEPHRRVTYEMKDNPN---FQIDASTGMITTKTTLDREVTPKYDVEVTAKDGVNK 2653 Query: 876 IKAMMQLSV 884 A++ ++V Sbjct: 2654 ESAILYITV 2662 Score = 241 bits (589), Expect = 3e-61 Identities = 231/822 (28%), Positives = 378/822 (45%), Gaps = 68/822 (8%) Query: 97 GALLTRASLDREK-VARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155 G +L + LD E+ +Y + VKAT+Q + D L ST + +++I+ ND++P F ++ Y Sbjct: 1989 GRILLNSLLDFERDQTQYNLKVKATEQ---IPDGLDSTVDVKIDVINANDHFPYFDQQLY 2045 Query: 156 TVSVDEDISVTDNPVIAKIKATDADVGANSA-----IRYAIIGGNTQM-QFSIDSLSGDV 209 +V + E +V ++ ++ A D D ++ + Y+I Q +F ID +G + Sbjct: 2046 SVQIPESTAV--GVLVQEVTAKDCDCLSSCTCSPGFLTYSIEPSKEQGGKFYIDPATGKI 2103 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269 S+ LDYE R + L + A D G S + + + +VNDN P F S ++ V+E Sbjct: 2104 SVSVALDYEDQRYHLLKVYATDKGKKSFQGLCFVNVTLTNVNDNRPTFLKSAYEFRVAEG 2163 Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329 G S+ V A DAD +TY+ G L ++D +G + + LD + Sbjct: 2164 AATGESLAIVVAVDAD---GDAVTYSK-----AGGA-LQFSVDQSTGVITLNSALD-PNK 2213 Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389 +Y L V A D G + + T V + E++P T + LT Sbjct: 2214 NQYTLQVMAKDSGGLTSTVSVTFNVADANNNVPQ---FTNCGTVSIRENDPRDTKITQLT 2270 Query: 390 ATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447 ATDAD ++ ++ Y I +++ FSI + G++ LD + + Y + A D Sbjct: 2271 ATDADRGQNGQITYSIEDASSQTLFSIEPRT--GVVRSLTSLDRENKDSYNAIIKAEDGS 2328 Query: 448 GRSDTA-------MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 + D + + IN+ D N+ P F A Y SVF AP G+ +L V ATD+D G Sbjct: 2329 SKQDESERLLWYCYLTINVEDVNDNRPYFLAAKYFGSVFSSAPNGSNILTVQATDADSGS 2388 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVI----NPQTGAITTNKLLDRETMSGYLLTVTARDG 556 NA+I Y+L S + D ++ NP + T K L E + + ++ Sbjct: 2389 NAKIKYALLD--SAGGLFRLDSSGILRTNTNPARLQLETGKKLLLEVSAKDVESIAGTQP 2446 Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616 G P+ TT +EI V N+ P F QQ+YTA+I E+ G++V+++ AT + I Sbjct: 2447 GKPT-KYTTQIEILV--SNEEPPKFSQQVYTASINENMETGSTVTRITATSS---TGAEI 2500 Query: 617 HYE-LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675 YE +D R + F + P G I T D E T++++ A D T STV V I Sbjct: 2501 SYENVDTNPRAKILFRVQP-DGYIITGDRPDYERGTTYNMQFAAKDKKT-LLYSTVKVVI 2558 Query: 676 KIEDINDSPPVF--ESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDS 732 I D+ND P F + + EN P T + ++A D D P+ V Y +K D+ Sbjct: 2559 NIIDVNDVSPAFLLAINTRNARVLENKPAPTKVISMKAIDDDGSEPHRRVTYEMK---DN 2615 Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP 792 +F ++ G + T LD E KY++ + A + I V D ND P Sbjct: 2616 PNFQIDASTGM----ITTKTTLDRE-VTPKYDVEVTAKDGVNKESAILYITVVDQNDQPP 2670 Query: 793 VMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTD--KLQYRILSGNNAN--LILLNETTG 847 V + +D P+G + A DADV + K+ Y I G+ I+ + G Sbjct: 2671 VFAPKSYAISVPEDS-PIGTSVLDIYATDADVGENAKITYFISKGDPEGKFSIVTSPVKG 2729 Query: 848 SMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889 + ++ +L+ T+EV+ TDG A++ ++++ + + Sbjct: 2730 ELVVNGKLDFETKSSYTLEVTATDGKFSDTAVVTVTIQDVND 2771 Score = 221 bits (539), Expect = 3e-55 Identities = 216/804 (26%), Positives = 348/804 (43%), Gaps = 79/804 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++NV D ND +PVFE QY ++ E T+VL ++ATD+D G N + Y ++ Sbjct: 237 RVNVEDANDQTPVFESSQYRETIAENTPIQTSVLRVRATDKDDGTNGGIYYYMK------ 290 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 NP V F ID +G + +LD ++T+ + A D+ P R Sbjct: 291 -NP-------------VNSYFTIDAITGVIRVAKTLDYNARDKHTLYISARDRGDP--PR 334 Query: 130 LSSTATIHVNI------------IDDNDNY-PQFSEKTYTVSVDEDISVTDNPVIAKIKA 176 S+ AT+ +++ D +N P F + YT S+ ED + ++A Sbjct: 335 TSAEATVEISLRENIQGWPLPDSADPKENTKPYFPQSRYTFSIREDFP--PKGALLVMRA 392 Query: 177 TDAD-VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS---YRLVIRAQDG 232 D D +G N +RY++ GN +F+ID SG V+L ++DYE + Y L + A D Sbjct: 393 ADNDPIGPNKRLRYSL-SGNGVSKFAIDPESGVVTLTDSVDYENTPNNHVYDLTVTATDQ 451 Query: 233 GSPSRSNTTQLLINIRDV--NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290 G S S TTQLLI I+DV N N+PRF +SEN+ + V A D+D N Sbjct: 452 GPGSLSATTQLLIEIQDVDENKNSPRFDPQQAILEISENLKQNSLVTTVSATDSDSVGNP 511 Query: 291 ELTYTMTDKDYTGNVDLPI-TIDPRSGWVYTS-GQLDRETQAKYQLLVTATDGGDPPRSA 348 G L + +D +G V + LDRE ++Y L+V A+D PRS+ Sbjct: 512 SSPDGKVVYSIVGGTGLGVFRVDSNTGEVKVAVPSLDREGTSQYTLVVKASDNATFPRSS 571 Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT 408 F Y ++ E++P GT V + DADE Y + T Sbjct: 572 RLFLMINLLDEDDNFPYFSQPIYIAQVPENQPSGTFVTVVVGRDADEGFNPSYTVI---T 628 Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDAN--NYA 466 G + G+I ++ LD + L V S S TA Q+NIT + N Sbjct: 629 PG-VPYKIEPSTGVIRTSKSLDQSELSTRELQVIVRVSTAGSKTADGQVNITVISKVNRP 687 Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 PVF+N PY+ V E+ + ++A DS ++ + Y+L+ D F + Sbjct: 688 PVFKNTPYSVKVPEEMGPLPNLFCIAAVDS---LSRPVQYTLAPGA--------DGLFEV 736 Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586 + +G + T + E + Y L + AR V ++ + + + V + D P F Y Sbjct: 737 DKDSGRLHTKNSFNYENVDRYNLRIEARTSSVQEVA-SASLTVEVTEEKD-LPKFSSDSY 794 Query: 587 TANIMEDALVGTSVSQ-VGATDADVGLNG-RIHYELDPKDREEGSFVIDPASG----VIR 640 + E A GT+++ + D+D + E +F + SG ++ Sbjct: 795 QLTVDESAAPGTTLAPGLLIIDSDTSSDQFDCSMEAITSLHTLYNFEVTQQSGRCFLRVQ 854 Query: 641 TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700 LD + + A D +T V + + D+ND P F + + ++ Sbjct: 855 AGGKLDAHLASKYTFNVRATDRNFRNMFATAQVEVNVIDVNDHKPEFLQESYWLSVPSST 914 Query: 701 PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760 P G+++ ++A D D G NA V Y + ++S F L +D +L T L +P Sbjct: 915 PAGSSLVTVQAEDMDIGTNAQVRYELLRQENSERFIL-----NDNNQLSTASTL---TPN 966 Query: 761 KKYELVIRAASPPLWNDVRVEILV 784 +Y+L+IRA+ N ++ V Sbjct: 967 VRYQLLIRASDSATRNPSSAQVPV 990 Score = 216 bits (527), Expect = 8e-54 Identities = 226/882 (25%), Positives = 385/882 (43%), Gaps = 78/882 (8%) Query: 21 PVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTADTLNPEDAXXXX 79 P F +Y S+RE +L ++A D D IG N + Y++ + + ++ Sbjct: 366 PYFPQSRYTFSIREDFPPKGALLVMRAADNDPIGPNKRLRYSL---SGNGVSK------- 415 Query: 80 XXXXXXVQDVFRIDGRSGALLTRASLDREKVAR---YTVLVKATDQASPVSDRLSSTATI 136 F ID SG + S+D E Y + V ATDQ P S ++ I Sbjct: 416 ----------FAIDPESGVVTLTDSVDYENTPNNHVYDLTVTATDQG-PGSLSATTQLLI 464 Query: 137 HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSA----IRYAI 191 + +D+N N P+F + + + E++ N ++ + ATD+D VG S+ + Y+I Sbjct: 465 EIQDVDENKNSPRFDPQQAILEISENLK--QNSLVTTVSATDSDSVGNPSSPDGKVVYSI 522 Query: 192 IGGNTQMQFSIDSLSGDVSL-VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 +GG F +DS +G+V + V +LD E Y LV++A D + RS+ L+IN+ D Sbjct: 523 VGGTGLGVFRVDSNTGEVKVAVPSLDREGTSQYTLVVKASDNATFPRSSRLFLMINLLDE 582 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 +DN P F ++ V EN P G + V DADEG N +YT+ +P Sbjct: 583 DDNFPYFSQPIYIAQVPENQPSGTFVTVVVGRDADEGFNP--SYTVITPG------VPYK 634 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I+P +G + TS LD+ + +L V ++A F Sbjct: 635 IEPSTGVIRTSKSLDQSELSTRELQVIVRVSTAGSKTADGQVNITVISKVNRPPVFKNTP 694 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 Y V++ E+ P + + A D+ + Y + G G F + +GR + + Sbjct: 695 YSVKVPEEMGPLPNLFCIAAVDS-LSRPVQYTLAPG-ADGLFEVDKDSGR--LHTKNSFN 750 Query: 431 FKQERRYVLTVSA-TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 ++ RY L + A T S +A + + +T+ + P F + Y +V E A GTT+ Sbjct: 751 YENVDRYNLRIEARTSSVQEVASASLTVEVTEEKDL-PKFSSDSYQLTVDESAAPGTTLA 809 Query: 490 V-VSATDSDVGINAQITYSLSSEISNEAVA--HHDQQFVINPQTGA----ITTNKLLDRE 542 + DSD T S + S EA+ H F + Q+G + LD Sbjct: 810 PGLLIIDSD-------TSSDQFDCSMEAITSLHTLYNFEVTQQSGRCFLRVQAGGKLDAH 862 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 S Y V A D ++ T VE++V+DVND++P F Q+ Y ++ G+S+ Sbjct: 863 LASKYTFNVRATDRNFRNMFATAQVEVNVIDVNDHKPEFLQESYWLSVPSSTPAGSSLVT 922 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 V A D D+G N ++ YEL ++ E F+++ + + T L + L A D Sbjct: 923 VQAEDMDIGTNAQVRYELLRQENSE-RFILND-NNQLSTASTLTPN--VRYQLLIRASDS 978 Query: 663 GT-PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 T P S+ V V++ + ++SP VF+ + E+S T + +A G ++ Sbjct: 979 ATRNPSSAQVPVYVSVYSPSESPIVFDKSSYNQNLPEDSSANTLVFTAKA--TRSGSSSG 1036 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA----ASPPLWND 777 + Y + GG ++ + + D ++ + LD+E+ + + + +RA + L ++ Sbjct: 1037 ITYELVGGYKQIGEAMFSIK-PDTGQVYLIKKLDFET-KSYFPIAVRAKYSGGAIELASE 1094 Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSG- 834 V ++ + DVNDN P + D F A DAD ++ Y I G Sbjct: 1095 VVAKVTIVDVNDNGPRFAFHESSKTVVIDSFSAKDTQLARALDADSGSLGEVTYGIDGGR 1154 Query: 835 NNANL-ILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE 875 + +NL +N TG + + ++ + V TDG + Sbjct: 1155 STSNLPFNINVKTGMIFATREILYTQGSSYIIIVVATDGATD 1196 Score = 205 bits (500), Expect = 2e-50 Identities = 202/718 (28%), Positives = 332/718 (46%), Gaps = 79/718 (11%) Query: 125 PVSDRLSSTA-TIHVNIIDDNDNYPQFS---EKTYTVSVDEDISVTDNPVIAKIKATDAD 180 P + L A T+ + I+D N+ +P F + Y V E +N ++ ++ A Sbjct: 103 PRGETLGGIAITLRITILDVNNFHPVFQLSQGEHYEGFVKE--GTAENTIVEGLEQCHAT 160 Query: 181 VGANSAIR-YAIIGGNTQMQFSIDSL---SGDVS----LVKTLDYEQVRS-----YRLVI 227 S IR Y+II GN + F ++++ SG S ++KT VR L + Sbjct: 161 DRDTSGIRGYSIISGNEKGYFKVETVQIGSGVTSRKFLVLKTTGKPIVRDDNNPYIMLTV 220 Query: 228 RAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG 287 + DGG+PS S T + +N+ D ND P F +S ++E+++EN PI S++RV+A D D+G Sbjct: 221 QVTDGGNPSHSGTANIRVNVEDANDQTPVFESSQYRETIAENTPIQTSVLRVRATDKDDG 280 Query: 288 VNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR- 346 N + Y M + V+ TID +G + + LD + K+ L ++A D GDPPR Sbjct: 281 TNGGIYYYMKNP-----VNSYFTIDAITGVIRVAKTLDYNARDKHTLYISARDRGDPPRT 335 Query: 347 SATATXX-------------XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393 SA AT F +Y + ED PP ++ + A D Sbjct: 336 SAEATVEISLRENIQGWPLPDSADPKENTKPYFPQSRYTFSIREDFPPKGALLVMRAADN 395 Query: 394 D---EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK---QERRYVLTVSATDSG 447 D + RL Y ++ GN +F+I ++ G++T+ +D++ Y LTV+ATD G Sbjct: 396 DPIGPNKRLRYSLS-GNGVSKFAIDPES--GVVTLTDSVDYENTPNNHVYDLTVTATDQG 452 Query: 448 GRSDTA----MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VG--- 499 S +A +++I D N +P F+ + E+ + V VSATDSD VG Sbjct: 453 PGSLSATTQLLIEIQDVDENKNSPRFDPQQAILEISENLKQNSLVTTVSATDSDSVGNPS 512 Query: 500 -INAQITYSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKLLDRETMSGYLLTVTARDGG 557 + ++ YS+ + + F ++ TG + LDRE S Y L V A D Sbjct: 513 SPDGKVVYSI---VGGTGLG----VFRVDSNTGEVKVAVPSLDREGTSQYTLVVKASDNA 565 Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617 S + I+++D +DN P F Q +Y A + E+ GT V+ V DAD G N + Sbjct: 566 TFPRSSRLFLMINLLDEDDNFPYFSQPIYIAQVPENQPSGTFVTVVVGRDADEGFNPS-Y 624 Query: 618 YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 + P + I+P++GVIRT+K+LD+ ++T +L+ + +++ V+I + Sbjct: 625 TVITP----GVPYKIEPSTGVIRTSKSLDQSELSTRELQVIVRVSTAGSKTADGQVNITV 680 Query: 678 EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL 737 + PPVF++ + + E + I A D P V Y++ G D F + Sbjct: 681 ISKVNRPPVFKNTPYSVKVPEEMGPLPNLFCIAAVDSLSRP---VQYTLAPGAD-GLFEV 736 Query: 738 ETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMK 795 + D L T +YE+ +Y L I A + + +V L +V + + K Sbjct: 737 D----KDSGRLHTKNSFNYENV-DRYNLRIEARTSSV-QEVASASLTVEVTEEKDLPK 788 Score = 194 bits (474), Expect = 2e-47 Identities = 230/908 (25%), Positives = 386/908 (42%), Gaps = 104/908 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-LKATDQDIGKNAEVEYTIELVTADT 69 +N+ D ND +P F Y S++EG + T +L + A D D G N ++ Y+I Sbjct: 1306 VNLTDINDDAPHFTSAIYRRSIKEGLAEDTEILPPVIAVDHDFGSNGKILYSI----LSG 1361 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 ++P+ F ID +G + T+ +LD E +T+ ++A D SP R Sbjct: 1362 VHPD------------WDKYFNIDSATGKITTKMTLDYETHKSHTLFIRAEDNGSP--KR 1407 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LS A + +++ID NDN P F+ Y + + + ++ ATD D G N I Y Sbjct: 1408 LSGIAQVDIDVIDRNDNSPVFAAAFYRAKIS--LGAVKGTSVLQVHATDLDSGQNGQITY 1465 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 +II GN + F+I+ G + + K+L + L + A+D + RS + + IN+ Sbjct: 1466 SIIQGNEEEAFTINE-QGVILVDKSLTTVAADKFSLKVEARDKNASPRSGSVTVEINVY- 1523 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 + D P F S V E VP + + V+A ++ LTYT+ +GN Sbjct: 1524 LPDGPPMFVVSPVTVYVKEGVPANHRVAGVKAATSEA-----LTYTLL----SGNEAGMF 1574 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP- 368 I+P +G + + +LD E + +Y+L + A D D RSA F+ Sbjct: 1575 RINPSTGSLDATRELDYEERRRYELKIEARDTRD--RSAMVELIIIVVNINDNKPTFVDI 1632 Query: 369 --GQYEVELA-----EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421 GQ + + D G + L A D D D I + + F I S RG Sbjct: 1633 VDGQIDRKAIGTCSPTDIAEGEVITRLGAFDRDGDEITF--IVPDDVKDLFKIDS---RG 1687 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 ++T +P++ + Y V A D+G V++ + + Y P + +V ED Sbjct: 1688 VVTAKKPIE-DLPKIYPFNVKALDNGEPPQETDVKVRLVFVH-YRP--DQKHVRVNVRED 1743 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 P G+ + V + I L E +N +V + ++ P LD Sbjct: 1744 TPTGSVIATVRRYFPN-----GIVSLLLPEKANFSVRANGDVILLTP----------LDY 1788 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 E+ + +TV G + ++ DVE+ V+DVNDN P++ ++ A + ++ G V Sbjct: 1789 ESQQFHRMTVREELG---NQTNDVDVEVVVLDVNDNRPIWMERERLARVNTNSRAGAQVY 1845 Query: 602 QVGATDADVGLNGRIHYEL-----DPKDRE----EGSFVIDPASGVIRTNKALDRESVAT 652 Q+ A D D G +G + Y+L D K + + F I+P + + +L + Sbjct: 1846 QLEARDEDDGSSGLVGYQLKSPSNDAKRKRRSPPQHPFTINPKTRQMEVAGSLKDQ---R 1902 Query: 653 HDLKAVAIDGGTPP-QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711 +DL A D G P S T+ +++ PP F F +SE++ + +G I A Sbjct: 1903 YDLDVFAFDYGIPRLTSDTITLNVDGSAAGQLPPRFSKVSYHFMVSEDAKYLSLVGIILA 1962 Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771 A + Y I G+ + F G + L ++ LD+E + +Y L ++A Sbjct: 1963 RSIS---GARLDYKIVSGNVGDKF---IAMGDGRILLNSL--LDFERDQTQYNLKVKATE 2014 Query: 772 ---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDK- 826 L + V V+I V + ND+ P D Q+ + VG V A D D Sbjct: 2015 QIPDGLDSTVDVKIDVINANDHFPYF-DQQLYSVQIPESTAVGVLVQEVTAKDCDCLSSC 2073 Query: 827 ------LQYRI-LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKA 878 L Y I S ++ TG +++S L+ + ++V TD G + Sbjct: 2074 TCSPGFLTYSIEPSKEQGGKFYIDPATGKISVSVALDYEDQRYHLLKVYATDKGKKSFQG 2133 Query: 879 MMQLSVRL 886 + ++V L Sbjct: 2134 LCFVNVTL 2141 Score = 170 bits (413), Expect = 5e-40 Identities = 202/754 (26%), Positives = 327/754 (43%), Gaps = 75/754 (9%) Query: 207 GDVSLVKTLDYE--QVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF------- 257 G V+ + ++YE + Y L + + G L I I DVN+ P F Sbjct: 77 GHVTSTQEIEYEIGKTNKYDLTVLQRPRGETLGGIAITLRITILDVNNFHPVFQLSQGEH 136 Query: 258 YTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDY--TGNVDLPITIDPR 314 Y +E +EN I + + A D D G+ + +K Y V + + R Sbjct: 137 YEGFVKEGTAENT-IVEGLEQCHATDRDTSGIRGYSIISGNEKGYFKVETVQIGSGVTSR 195 Query: 315 SGWVY-TSGQ-LDRETQAKYQLL-VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371 V T+G+ + R+ Y +L V TDGG+P S TA F QY Sbjct: 196 KFLVLKTTGKPIVRDDNNPYIMLTVQVTDGGNPSHSGTANIRVNVEDANDQTPVFESSQY 255 Query: 372 EVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 +AE+ P T V+ + ATD D+ N Y F+I + G+I VA+ LD Sbjct: 256 RETIAENTPIQTSVLRVRATDKDDGTNGGIYYYMKNPVNSYFTIDAIT--GVIRVAKTLD 313 Query: 431 FKQERRYVLTVSATDSGG---RSDTAMVQINITD-------------ANNYAPVFENAPY 474 + ++ L +SA D G S A V+I++ + N P F + Y Sbjct: 314 YNARDKHTLYISARDRGDPPRTSAEATVEISLRENIQGWPLPDSADPKENTKPYFPQSRY 373 Query: 475 TASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 T S+ ED P +LV+ A D+D +G N ++ YSLS + +F I+P++G + Sbjct: 374 TFSIREDFPPKGALLVMRAADNDPIGPNKRLRYSLS--------GNGVSKFAIDPESGVV 425 Query: 534 TTNKLLDRETMSG---YLLTVTARDGGVPSLSDTTD--VEISVVDVNDNEPVFKQQLYTA 588 T +D E Y LTVTA D G SLS TT +EI VD N N P F Q Sbjct: 426 TLTDSVDYENTPNNHVYDLTVTATDQGPGSLSATTQLLIEIQDVDENKNSPRFDPQQAIL 485 Query: 589 NIMEDALVGTSVSQVGATDAD-VG----LNGRIHYELDPKDREEGSFVIDPASGVIRTN- 642 I E+ + V+ V ATD+D VG +G++ Y + G F +D +G ++ Sbjct: 486 EISENLKQNSLVTTVSATDSDSVGNPSSPDGKVVYSI-VGGTGLGVFRVDSNTGEVKVAV 544 Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 +LDRE + + L A D T P+SS + + I + D +D+ P F + EN P Sbjct: 545 PSLDREGTSQYTLVVKASDNATFPRSSRLFLMINLLDEDDNFPYFSQPIYIAQVPENQPS 604 Query: 703 GTTIGEIRAHDPDEGPN---AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759 GT + + D DEG N V+ + + ++ + T + D++EL T Sbjct: 605 GTFVTVVVGRDADEGFNPSYTVITPGVPYKIEPSTGVIRTSKSLDQSELST--------- 655 Query: 760 RKKYELVIRAASP-PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA 818 ++ ++++R ++ D +V I V + PV K+ ++ P+ + A Sbjct: 656 -RELQVIVRVSTAGSKTADGQVNITVISKVNRPPVFKNTPYSVKVPEEMGPLPNLFCIAA 714 Query: 819 YDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN-TNVPKLATMEVSVTDGVNEIK 877 D+ ++ +QY + G + L +++ +G + N NV + + T V E+ Sbjct: 715 VDS-LSRPVQYTLAPGAD-GLFEVDKDSGRLHTKNSFNYENVDRYNLRIEARTSSVQEV- 771 Query: 878 AMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSP 911 A L+V +TEE L + +T ++ +P Sbjct: 772 ASASLTVE-VTEEKDLPKFSSDSYQLTVDESAAP 804 Score = 160 bits (388), Expect = 6e-37 Identities = 111/344 (32%), Positives = 166/344 (48%), Gaps = 39/344 (11%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVT 66 ++N+ D ND++P F Y V E SGT+V+ ++A D D G NA++ Y + Sbjct: 2871 RVNLTDVNDNAPRFPASPYIGYVEENKPSGTSVMYIQAVDDDDPLAGGNAKLSYEL---- 2926 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA-RYTVLVKATDQASP 125 D F ID SG + T+ + DRE+ ++ V VKATD +P Sbjct: 2927 ----------------TDSAGDKFSIDPLSGLIKTKVTFDREQTPNKFKVRVKATDAGNP 2970 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 RLS++ +++ D ND+ P+F+EK Y SV E + + ++ ATD DVG N+ Sbjct: 2971 ---RLSASVDGIIHVSDANDHKPKFTEKFYRGSVAE--NAPPGYSVLRVTATDEDVGPNA 3025 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQL 243 + ++ GN F ID +G V + LDYE+ + Y + + D G P T + Sbjct: 3026 EFEFVVVQGNDPHAFYIDPFNGTVLVSGILDYEKKKEYTITLTVADRGMPPLQGDETAYV 3085 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 +I I D NDNAP F ++ SV E+V ++ V A D D G N T+ + D Sbjct: 3086 VIEILDANDNAPEFIPKIYNASVLEDVGARQPVLTVTAVDKDSGPNGNFTFAI---DPRS 3142 Query: 304 NVDLPITIDPRS-----GWVYTSGQLDRETQAKYQLLVTATDGG 342 + D TI+P G + T LD+E + L VTATD G Sbjct: 3143 DPDDAFTIEPNPNNASIGIIRTRVPLDQEKTPSFHLKVTATDAG 3186 Score = 87.0 bits (206), Expect = 7e-15 Identities = 81/271 (29%), Positives = 112/271 (41%), Gaps = 30/271 (11%) Query: 1089 CQG--CSIDAAYTTAVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLY-- 1144 C G C Y +CE+ R+F +S++ P L L+ +F T+T GLL+Y Sbjct: 3599 CPGFVCKCPTGYHGPLCEMTTRTFYGNSYIWLPKLMTYSLSDLEFEFMTKTADGLLVYQG 3658 Query: 1145 ---NGRYNERHDFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEI 1201 G N DF+A+ L RGG L S L ++ + DG WHTV++ Sbjct: 3659 PEREGANNGLKDFIAVVL------RGGRVELFVSLGLDPVTVKMDKGPRLDDGEWHTVQV 3712 Query: 1202 EYFNRTITMILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHR--FLDLT 1259 + I +I+D C L L D RK C + R FLD Sbjct: 3713 LRNMKDIEIIIDRCSTAL-LEHKPD-----GTVVENRK----SCHVYGRMLGRSVFLDGF 3762 Query: 1260 GPLQIGGLPNIPSSF-QVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCS 1318 GPLQIGG+ N F + F GC+ + +H DL + + GC + S C Sbjct: 3763 GPLQIGGVSNPNMDFPDIPYTGFKGCVRNIKDNHNLYDLKNPLKVVNAPEGC-QLASACP 3821 Query: 1319 SAPCYNGAECSDLW-DTYICDCKEGHTGKDC 1348 C N C L IC C G++GK C Sbjct: 3822 E--CKNDGYCEPLMARDSICVCNPGYSGKHC 3850 Score = 37.9 bits (84), Expect = 4.0 Identities = 26/85 (30%), Positives = 37/85 (43%), Gaps = 9/85 (10%) Query: 1477 SDVGFFEGCIQDVRIGTAQSLLNRPTV---RENVRDGCQSRADCMLSICPPYSKCVTSWD 1533 S +G F GCI + A ++ + P++ R+NV DGC C+ + C CV + Sbjct: 4063 SVLGDFGGCIAGTSVNGA-NMESDPSIKVHRQNVLDGCP----CLSNFCANGGTCVDAMP 4117 Query: 1534 SSTCTCEAGRVGPQCVSACELGPCG 1558 C C G GP C P G Sbjct: 4118 PY-CICAPGWTGPLCTIVVTAPPVG 4141 >UniRef50_UPI0000E7FC61 Cluster: PREDICTED: similar to dachsous 1; n=3; Gallus gallus|Rep: PREDICTED: similar to dachsous 1 - Gallus gallus Length = 2641 Score = 345 bits (847), Expect = 1e-92 Identities = 281/903 (31%), Positives = 418/903 (46%), Gaps = 67/903 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTAD 68 QI V DCND +P F V E A +G++V T +A D D +G N++V Y + Sbjct: 1385 QILVQDCNDQAPTFPEDPITIVVPENAQAGSSVFTFQALDGDGVGPNSQVRYAL------ 1438 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 L E F +D RSG L SLDRE VA + ++V+ATDQA VS Sbjct: 1439 -LRQEPPGAP-----------FHLDSRSGLLSLHQSLDREAVASFLLVVEATDQARNVSQ 1486 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 R SS T V + D NDN P F VSV ED V + A D D+G N + Sbjct: 1487 RRSSAVTARVFVTDVNDNAPVFLSPA-AVSVTEDRPT--GFVALHVVAQDNDLGENGRVS 1543 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y++ GN +F ++ +G +S+V+ L+ E+V + L + A D G P RS T L I + Sbjct: 1544 YSLRAGNGDGRFHLNPSTGALSVVRALNREEVVQHNLTVVAADHGFPRRSATQLLSILVL 1603 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 DVND AP F ++ V EN+P G +++V A D D G N ++T Y G P Sbjct: 1604 DVNDEAPTFEKPEYEAHVMENLPAGSPVLQVLATDRDLGANGQVT-------YGGLSGGP 1656 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 +I P++G + T+ LDRE Q ++ L+V A DGG PP + AT Sbjct: 1657 FSIHPQTGLIVTTHPLDREEQEQHVLMVYAQDGGLPPNLSKATVRITVGDENDHTPQLES 1716 Query: 369 GQYEVELAEDEPPGTPVVTLTAT--DADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 VE+ E++ + TL AT D DE+ RL Y + G+ F + + G+++ A Sbjct: 1717 ESCSVEVPENQ-SRVALYTLRATDPDGDENGRLEYRVADGDPEQDFILDPVS--GVLSTA 1773 Query: 427 QPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 + LD +Q Y LTV D G RS T V + + D N+ AP F A Y V ED P+ Sbjct: 1774 RALDREQVAFYSLTVVVQDHGTPPRSATMTVNVRVLDLNDNAPGFAQASYVVEVPEDLPV 1833 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 G+ VL + A D D G N Q+TY L NE++ F I PQ+G I + + LDRE Sbjct: 1834 GSLVLQLEAEDPDEGTNGQVTYYL----GNESLG----MFQIEPQSGRIRSAQELDRERQ 1885 Query: 545 SGYLLTVTARDGGV-PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 Y A D S V ++V DVND+ P F T ++ + V+ + Sbjct: 1886 PSYSFLAKAVDSAPWEPKSAAVRVTVTVQDVNDHAPAFLHSPVTVSLSRHTPLKQVVATM 1945 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 A D D G N I Y L + +F I+ +G I+ + L S L +A D G Sbjct: 1946 RAEDRDAGANASILYRLATPN---SAFSINSYTGDIQLLQPLSSLSQRQRTLFILATDLG 2002 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 P SST +V I +++ F + EN+ GT + I+A G + + Sbjct: 2003 QPALSSTGVVVIHVQEEPYRGLRFPRSTSEVVLPENAAPGTAVTSIQAVHMG-GSSGRIT 2061 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEIL 783 YSI G++ N+F ++ G+ + + +D + SPR + LV++A + + + + + Sbjct: 2062 YSIISGNEKNAFLIQPSSGAISVQDSSSLDFE-ASPRLR--LVVQAETTASFGFMAINLN 2118 Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANL-ILL 842 + DVNDN P FQ+ NY V +YD+ V L + G N + + Sbjct: 2119 LQDVNDNLP---RFQL--QNY-----VAFIWESQSYDSPVIQVLADDLDQGMNGQVTYAI 2168 Query: 843 NET---TGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVR 899 N++ TG + PQ T + A ++ + + M + L + + Sbjct: 2169 NQSLPMTGLYHIDPQTGT-ITTAAILDREIWSQTRLVVTAMDRGTPPLVGSATLTVVVMD 2227 Query: 900 LND 902 +ND Sbjct: 2228 IND 2230 Score = 311 bits (763), Expect = 2e-82 Identities = 254/806 (31%), Positives = 374/806 (46%), Gaps = 54/806 (6%) Query: 92 IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151 ID G + T LDRE Y+ + + T +++ + D ND+ P F Sbjct: 70 IDENRGIIKTARVLDRETRDHYSFIAVTPE---------GITVEVNIQVNDINDHAPAFP 120 Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG---- 207 ++ T + E V + A DAD G + Y I G N F +++ G Sbjct: 121 KQHSTFQIPEHTPVGSRFPLDP--AFDADSGLLNTQGYVIKGDNVGQAFRLETRRGPNGV 178 Query: 208 ---DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 D+ + LD E SY LV+ A DGG+P RS+ L ++I+D+NDNAP F S + Sbjct: 179 LYLDLVVSNVLDRENRSSYSLVLEAYDGGTPPRSSQMTLDVSIQDINDNAPAFNQSRYHT 238 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 +SEN+ G SI++V A DADEG N ++ Y + + + D TID R+G + + L Sbjct: 239 LISENLKPGSSILQVFASDADEGDNGDVIYEINRRQ--SDPDQYFTIDSRTGVIKLNKGL 296 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX----XXXXXFMPGQYEVELAEDEP 380 D E + ++L+V A D P TA F+ +++E Sbjct: 297 DYEVRKVHELVVQARDRAVHPEVTTAFVTIHVRDYNDNQPTMTIIFLSEDGSPQISEGAQ 356 Query: 381 PGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ-NGRGLITVAQPLDFKQERRYVL 439 PG V ++ +D D + +T G+F++T++ N LI V Q LD ++ Y L Sbjct: 357 PGQYVARISVSDPDYGEYSNVNVTLEGGDGKFALTTKDNIIYLICVDQLLDREERDSYDL 416 Query: 440 TVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496 V+ATDSG R+++ V + + D N+ P+F+ Y S+ E G+ VL V+A D Sbjct: 417 RVTATDSGTPPLRAESTFV-LQVIDINDNPPLFDQQEYKQSIPEVVYPGSFVLQVTARDK 475 Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556 D G N ++ YS+ S++ H F I+P TG ITT LD E LTV A D Sbjct: 476 DQGPNGEVQYSIVH--SHDT---HSSWFAIDPATGIITTAAPLDYEKDPQPQLTVLATDR 530 Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616 G P+LS + V +++ DVNDNEPVF+ Y ++ E+ VGT QV ATDAD GL G + Sbjct: 531 GTPALSSSAVVLVALQDVNDNEPVFRSNFYNVSLKENTPVGTCFLQVTATDADSGLFGSL 590 Query: 617 HYELDP--KDREEGSFVIDPASGVIRTNKALDR-ESVATHDLKAVAIDGGTPPQSSTVIV 673 Y L F ID +G + T + LDR E + +D A+DGG +S V V Sbjct: 591 SYSLGSGIGSVVPTQFSIDKHTGHLCTTQPLDRDEGTSAYDFTITAVDGG--GLNSMVYV 648 Query: 674 HIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN 733 + +EDIND+ PVF IS S GT + + AHD DEG + V Y I G+ Sbjct: 649 KVFLEDINDNRPVFYPLDYAASISTQSMPGTAVLRVTAHDKDEGMHGKVTYRIVLGNSPP 708 Query: 734 SFSLETRQGSDKAELVTMVDLDYESPRKK---YELVIRA---ASPPLWNDVRVEILVTDV 787 FSL G ++ L + K +LVI A + RV I V + Sbjct: 709 LFSLNKDTG--------VISLSWSLSGKANTLVQLVISAEDGGGLQAQPNARVNISVVEG 760 Query: 788 NDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD-ADVTDKLQYRILSGNNANLILLNETT 846 + PV + Q F +D G V A + TD + Y I SG+ ++ T Sbjct: 761 TVSPPVFEQAQYFFTVPEDMLQGASVGAVRAQNPPGHTDDIFYSISSGDPHGYFSIDSDT 820 Query: 847 GSMTLSPQLNTNVPKLATMEVSVTDG 872 G + S L+ + ++V G Sbjct: 821 GQLHTSLPLDHESQAVLILDVQARSG 846 Score = 310 bits (762), Expect = 3e-82 Identities = 257/860 (29%), Positives = 393/860 (45%), Gaps = 69/860 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I VLD ND +P FE +YEA V E +G+ VL + ATD+D+G N +V T L Sbjct: 1600 ILVLDVNDEAPTFEKPEYEAHVMENLPAGSPVLQVLATDRDLGANGQV-------TYGGL 1652 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F I ++G ++T LDRE+ ++ ++V A D P + Sbjct: 1653 SGGP---------------FSIHPQTGLIVTTHPLDREEQEQHVLMVYAQDGGLPPN--- 1694 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S AT+ + + D+ND+ PQ ++ +V V E+ S + ++ATD D N + Y Sbjct: 1695 LSKATVRITVGDENDHTPQLESESCSVEVPENQS---RVALYTLRATDPDGDENGRLEYR 1751 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + G+ + F +D +SG +S + LD EQV Y L + QD G+P RS T + + + D+ Sbjct: 1752 VADGDPEQDFILDPVSGVLSTARALDREQVAFYSLTVVVQDHGTPPRSATMTVNVRVLDL 1811 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI- 309 NDNAP F + + V E++P+G +++++A D DEG N ++TY Y GN L + Sbjct: 1812 NDNAPGFAQASYVVEVPEDLPVGSLVLQLEAEDPDEGTNGQVTY------YLGNESLGMF 1865 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD-PPRSATATXXXXXXXXXXXXXXFMP 368 I+P+SG + ++ +LDRE Q Y L A D P+SA F+ Sbjct: 1866 QIEPQSGRIRSAQELDRERQPSYSFLAKAVDSAPWEPKSAAVRVTVTVQDVNDHAPAFLH 1925 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 V L+ P V T+ A D D FSI S G I + QP Sbjct: 1926 SPVTVSLSRHTPLKQVVATMRAEDRDAGANASILYRLATPNSAFSINSYTGD--IQLLQP 1983 Query: 429 LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 L +R+ L + ATD G S T +V I++ + F + + E+A GT Sbjct: 1984 LSSLSQRQRTLFILATDLGQPALSSTGVVVIHVQEEPYRGLRFPRSTSEVVLPENAAPGT 2043 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT--NKLLDRETM 544 V + A G + +ITYS+ S NE A F+I P +GAI+ + LD E Sbjct: 2044 AVTSIQAVHMG-GSSGRITYSIIS--GNEKNA-----FLIQPSSGAISVQDSSSLDFEAS 2095 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 L V A + + +++ DVNDN P F+ Q Y A I E + V QV Sbjct: 2096 PRLRLVVQAE---TTASFGFMAINLNLQDVNDNLPRFQLQNYVAFIWESQSYDSPVIQVL 2152 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 A D D G+NG++ Y ++ G + IDP +G I T LDRE + L A+D GT Sbjct: 2153 ADDLDQGMNGQVTYAINQSLPMTGLYHIDPQTGTITTAAILDREIWSQTRLVVTAMDRGT 2212 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 PP + + + + DIND+ P + EN +GT I ++ +D D GP A+ + Sbjct: 2213 PPLVGSATLTVVVMDINDNSPTIPFP-WEVRVPENMLLGTQIAQLTGNDVDSGP-ALSYT 2270 Query: 725 SIKGGD-----DSNSFSLETRQGSD-------KAELVTMVDLDYESPRKKYELVIRAASP 772 + GD + + +G D EL + + DYE K ++L++RA Sbjct: 2271 LVLDGDAYAVLEQPAGGPGVAEGRDAFAINSSSGELRSRLTFDYER-AKAFQLLVRATDA 2329 Query: 773 PLWN-DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRI 831 + V V +LVT ++ P+ F + GRV A D D Sbjct: 2330 GNASATVTVRVLVTGEDEYDPIFLSPSFSFEVPEGAHKGQSIGRVLATDEDEGADGVVLY 2389 Query: 832 LSGNNANLILLNETTGSMTL 851 + +N+TTG++ L Sbjct: 2390 SLAKPSPYFAINQTTGTIYL 2409 Score = 304 bits (746), Expect = 2e-80 Identities = 253/875 (28%), Positives = 400/875 (45%), Gaps = 53/875 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +++ D ND++P F +Y + E G+++L + A+D D G N +V Y I +D Sbjct: 219 VSIQDINDNAPAFNQSRYHTLISENLKPGSSILQVFASDADEGDNGDVIYEINRRQSD-- 276 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P+ F ID R+G + LD E + ++V+A D+A V + Sbjct: 277 -PDQ--------------YFTIDSRTGVIKLNKGLDYEVRKVHELVVQARDRA--VHPEV 319 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP--VIAKIKATDADVGANSAIR 188 +TA + +++ D NDN P + + IS P +A+I +D D G S + Sbjct: 320 -TTAFVTIHVRDYNDNQPTMTIIFLSEDGSPQISEGAQPGQYVARISVSDPDYGEYSNVN 378 Query: 189 YAIIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 + GG+ + + D++ + + + LD E+ SY L + A D G+P + ++ + Sbjct: 379 VTLEGGDGKFALTTKDNIIYLICVDQLLDREERDSYDLRVTATDSGTPPLRAESTFVLQV 438 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 D+NDN P F +++S+ E V G +++V A D D+G N E+ Y++ T + Sbjct: 439 IDINDNPPLFDQQEYKQSIPEVVYPGSFVLQVTARDKDQGPNGEVQYSIVHSHDTHS--S 496 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 IDP +G + T+ LD E + QL V ATD G P S++A F Sbjct: 497 WFAIDPATGIITTAAPLDYEKDPQPQLTVLATDRGTPALSSSAVVLVALQDVNDNEPVFR 556 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEI---TGGNTRGRFSITSQNGRGL 422 Y V L E+ P GT + +TATDAD L Y + G +FSI G Sbjct: 557 SNFYNVSLKENTPVGTCFLQVTATDADSGLFGSLSYSLGSGIGSVVPTQFSIDKHTGH-- 614 Query: 423 ITVAQPLDFKQ-ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 + QPLD + Y T++A D GG + V++ + D N+ PVF Y AS+ Sbjct: 615 LCTTQPLDRDEGTSAYDFTITAVDGGGLNSMVYVKVFLEDINDNRPVFYPLDYAASISTQ 674 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 + GT VL V+A D D G++ ++TY + + + F +N TG I+ + L Sbjct: 675 SMPGTAVLRVTAHDKDEGMHGKVTYRI-------VLGNSPPLFSLNKDTGVISLSWSLSG 727 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 + + L ++A DGG V ISVV+ + PVF+Q Y + ED L G SV Sbjct: 728 KANTLVQLVISAEDGGGLQAQPNARVNISVVEGTVSPPVFEQAQYFFTVPEDMLQGASVG 787 Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 V A + G I Y + D G F ID +G + T+ LD ES A L V Sbjct: 788 AVRAQNPP-GHTDDIFYSISSGD-PHGYFSIDSDTGQLHTSLPLDHESQAVLILD-VQAR 844 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 G+PP S V I + D+ND+ P F S + + E + GTT+ ++A D D G N Sbjct: 845 SGSPPAYSNTRVKISVSDVNDNAPTFPSPSDSILLPEATEPGTTVYTLQAEDRDNGANGQ 904 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPRKKYELVIR-AASPPLWNDVR 779 V++ + G D +FS+E G+ LV + L YE S + +V R + P L + Sbjct: 905 VNFELVSGGD-GTFSVERSSGA--VRLVGV--LQYEASAAYRLSIVARDSGVPQLSSTFT 959 Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADVTD-KLQYRILSGNNA 837 + + V +DN P+ D ++ PV F +V A D D L Y + + +A Sbjct: 960 LLVHVQAEHDNGPIF-DTLTYRVEVREGVPVSTRFLQVRALARDAEDVTLTYHLRADGDA 1018 Query: 838 NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 + +G + + L+ L + V + G Sbjct: 1019 ASFGIMSESGWLYVKSALDRETRDLYVLTVLASAG 1053 Score = 284 bits (696), Expect = 3e-74 Identities = 245/893 (27%), Positives = 397/893 (44%), Gaps = 66/893 (7%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 D ND+ PVF Y S++E GT L + ATD D G + Y++ Sbjct: 547 DVNDNEPVFRSNFYNVSLKENTPVGTCFLQVTATDADSGLFGSLSYSL------------ 594 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREK-VARYTVLVKATDQASPVSDRLSST 133 V F ID +G L T LDR++ + Y + A D L+S Sbjct: 595 ----GSGIGSVVPTQFSIDKHTGHLCTTQPLDRDEGTSAYDFTITAVDGGG-----LNSM 645 Query: 134 ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG 193 + V + D NDN P F Y S+ S+ V+ ++ A D D G + + Y I+ Sbjct: 646 VYVKVFLEDINDNRPVFYPLDYAASISTQ-SMPGTAVL-RVTAHDKDEGMHGKVTYRIVL 703 Query: 194 GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDN 253 GN+ FS++ +G +SL +L + +LVI A+DGG ++ I++ + + Sbjct: 704 GNSPPLFSLNKDTGVISLSWSLSGKANTLVQLVISAEDGGGLQAQPNARVNISVVEGTVS 763 Query: 254 APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313 P F + + +V E++ G S+ V+A + G ++ Y+++ D G +ID Sbjct: 764 PPVFEQAQYFFTVPEDMLQGASVGAVRAQN-PPGHTDDIFYSISSGDPHGY----FSIDS 818 Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373 +G ++TS LD E+QA L V A G P S T P + Sbjct: 819 DTGQLHTSLPLDHESQAVLILDVQARSGSPPAYSNTRVKISVSDVNDNAPTFPSPSD-SI 877 Query: 374 ELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431 L E PGT V TL A D D + ++++E+ G G FS+ + G + + L + Sbjct: 878 LLPEATEPGTTVYTLQAEDRDNGANGQVNFELVSGGD-GTFSV--ERSSGAVRLVGVLQY 934 Query: 432 KQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 + Y L++ A DSG S T + +++ ++ P+F+ Y V E P+ T L Sbjct: 935 EASAAYRLSIVARDSGVPQLSSTFTLLVHVQAEHDNGPIFDTLTYRVEVREGVPVSTRFL 994 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 V A D + +TY L ++ +A + F I ++G + LDRET Y+L Sbjct: 995 QVRALARDAE-DVTLTYHLRAD--GDAAS-----FGIMSESGWLYVKSALDRETRDLYVL 1046 Query: 550 TVTARDGGVPS-----LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 TV A GG S + T+ V IS+ D NDN P ++ Y + E+ G+SV +V Sbjct: 1047 TVLASAGGSGSGGEARKTGTSTVRISITDENDNSPRLSEERYFFTVPENQAPGSSVGRVM 1106 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 A+D D G N R+ Y L D +F+I +G + T +LDRE +++ L + DGG Sbjct: 1107 ASDRDAGQNSRLTYRLLQHD---SNFLIHTQTGELSTKHSLDRELQSSYQLLVIVQDGGA 1163 Query: 665 PPQSSTVIVHIKIEDINDSPPVF----ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 PP+S+T +++ + D ND+ PVF L + E P G + ++A DPDEG N Sbjct: 1164 PPRSATGTIYVTVLDENDNAPVFLHITGGQELPVQVLEEKPSGLLVASLQAKDPDEGENG 1223 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWND 777 + YS+ G + F+L T G EL T L + R +Y + A+ P Sbjct: 1224 TITYSLTGA-WAERFTLHTATG----ELRTATVL-RRADRAEYVFTVTASDRGMVPCTTS 1277 Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNA 837 V I V + P + + P G V DA +L Y ++ G Sbjct: 1278 AIVRIQVLPSSRLLPRPDATVLTLQPLEGVRPGSVIGSVAPPDAPARGQLTYTVIGGGGD 1337 Query: 838 NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEE 890 +++ TG + + +L+ T++VS D + + + V+++ ++ Sbjct: 1338 GTFVVDSVTGEIYAARELDYEARARHTLQVSAEDTQHGYPSSRLVLVQILVQD 1390 Score = 274 bits (671), Expect = 3e-71 Identities = 235/806 (29%), Positives = 368/806 (45%), Gaps = 67/806 (8%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 ++ ++ + D ND+ PVF Y AS+ + GT VL + A D+D G + +V Y I L Sbjct: 646 VYVKVFLEDINDNRPVFYPLDYAASISTQSMPGTAVLRVTAHDKDEGMHGKVTYRIVLGN 705 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 + L F ++ +G + SL + +++ A D Sbjct: 706 SPPL-------------------FSLNKDTGVISLSWSLSGKANTLVQLVISAEDGGGL- 745 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 + A +++++++ + P F + Y +V ED+ + ++A + G Sbjct: 746 --QAQPNARVNISVVEGTVSPPVFEQAQYFFTVPEDM--LQGASVGAVRAQNPP-GHTDD 800 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 I Y+I G+ FSIDS +G + LD+E L ++A+ G P+ SNT ++ I+ Sbjct: 801 IFYSISSGDPHGYFSIDSDTGQLHTSLPLDHESQAVLILDVQARSGSPPAYSNT-RVKIS 859 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + DVNDNAP F + + E G ++ +QA D D G N ++ + + +G D Sbjct: 860 VSDVNDNAPTFPSPSDSILLPEATEPGTTVYTLQAEDRDNGANGQVNFELV----SGG-D 914 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 +++ SG V G L E A Y+L + A D G P S+T T F Sbjct: 915 GTFSVERSSGAVRLVGVLQYEASAAYRLSIVARDSGVPQLSSTFTLLVHVQAEHDNGPIF 974 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDAD-EDNRLHYEITGGNTRGRFSITSQNGRGLITV 425 Y VE+ E P T + + A D ED L Y + F I S++G + V Sbjct: 975 DTLTYRVEVREGVPVSTRFLQVRALARDAEDVTLTYHLRADGDAASFGIMSESG--WLYV 1032 Query: 426 AQPLDFKQERRYVLTVSAT----DSGG---RSDTAMVQINITDANNYAPVFENAPYTASV 478 LD + YVLTV A+ SGG ++ T+ V+I+ITD N+ +P Y +V Sbjct: 1033 KSALDRETRDLYVLTVLASAGGSGSGGEARKTGTSTVRISITDENDNSPRLSEERYFFTV 1092 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 E+ G++V V A+D D G N+++TY L HD F+I+ QTG ++T Sbjct: 1093 PENQAPGSSVGRVMASDRDAGQNSRLTYRL---------LQHDSNFLIHTQTGELSTKHS 1143 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ----QLYTANIMEDA 594 LDRE S Y L V +DGG P S T + ++V+D NDN PVF Q ++E+ Sbjct: 1144 LDRELQSSYQLLVIVQDGGAPPRSATGTIYVTVLDENDNAPVFLHITGGQELPVQVLEEK 1203 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654 G V+ + A D D G NG I Y L E F + A+G +RT L R A + Sbjct: 1204 PSGLLVASLQAKDPDEGENGTITYSLTGAWAER--FTLHTATGELRTATVLRRADRAEYV 1261 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 A D G P +++ IV I++ + P ++ LT E G+ IG + P Sbjct: 1262 FTVTASDRGMVPCTTSAIVRIQVLPSSRLLPRPDATVLTLQPLEGVRPGSVIGSVA--PP 1319 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP-- 772 D + Y++ GG +F +++ G E+ +LDYE+ R ++ L + A Sbjct: 1320 DAPARGQLTYTVIGGGGDGTFVVDSVTG----EIYAARELDYEA-RARHTLQVSAEDTQH 1374 Query: 773 --PLWNDVRVEILVTDVNDNAPVMKD 796 P V V+ILV D ND AP + Sbjct: 1375 GYPSSRLVLVQILVQDCNDQAPTFPE 1400 Score = 269 bits (660), Expect = 6e-70 Identities = 248/872 (28%), Positives = 396/872 (45%), Gaps = 81/872 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+V++ PVFE QY +V E G +V ++A + G ++ Y+I + D Sbjct: 755 ISVVEGTVSPPVFEQAQYFFTVPEDMLQGASVGAVRAQNPP-GHTDDIFYSIS--SGDP- 810 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F ID +G L T LD E A + V+A + P Sbjct: 811 ----------------HGYFSIDSDTGQLHTSLPLDHESQAVLILDVQARSGSPPAY--- 851 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S + +++ D NDN P F + ++ + E + + ++A D D GAN + + Sbjct: 852 -SNTRVKISVSDVNDNAPTFPSPSDSILLPE--ATEPGTTVYTLQAEDRDNGANGQVNFE 908 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 ++ G FS++ SG V LV L YE +YRL I A+D G P S+T LL++++ Sbjct: 909 LVSGGDGT-FSVERSSGAVRLVGVLQYEASAAYRLSIVARDSGVPQLSSTFTLLVHVQAE 967 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM-TDKDYTGNVDLPI 309 +DN P F T ++ V E VP+ ++V+A A + + LTY + D D Sbjct: 968 HDNGPIFDTLTYRVEVREGVPVSTRFLQVRAL-ARDAEDVTLTYHLRADGDAAS-----F 1021 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTAT-----DGGDPPRSATATXXXXXXXXXXXXX 364 I SGW+Y LDRET+ Y L V A+ GG+ ++ T+T Sbjct: 1022 GIMSESGWLYVKSALDRETRDLYVLTVLASAGGSGSGGEARKTGTSTVRISITDENDNSP 1081 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGL 422 +Y + E++ PG+ V + A+D D +++RL Y + ++ F I +Q G Sbjct: 1082 RLSEERYFFTVPENQAPGSSVGRVMASDRDAGQNSRLTYRLLQHDSN--FLIHTQTGE-- 1137 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAP----YTA 476 ++ LD + + Y L V D G RS T + + + D N+ APVF + Sbjct: 1138 LSTKHSLDRELQSSYQLLVIVQDGGAPPRSATGTIYVTVLDENDNAPVFLHITGGQELPV 1197 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 V E+ P G V + A D D G N ITYSL+ + ++F ++ TG + T Sbjct: 1198 QVLEEKPSGLLVASLQAKDPDEGENGTITYSLTGAWA--------ERFTLHTATGELRTA 1249 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 +L R + Y+ TVTA D G+ + + V I V+ + P + T +E Sbjct: 1250 TVLRRADRAEYVFTVTASDRGMVPCTTSAIVRIQVLPSSRLLPRPDATVLTLQPLEGVRP 1309 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 G+ + V DA G++ Y + + G+FV+D +G I + LD E+ A H L+ Sbjct: 1310 GSVIGSVAPPDAPA--RGQLTYTVIGGGGD-GTFVVDSVTGEIYAARELDYEARARHTLQ 1366 Query: 657 AVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 A D P S V+V I ++D ND P F D +T + EN+ G+++ +A D D Sbjct: 1367 VSAEDTQHGYPSSRLVLVQILVQDCNDQAPTFPEDPITIVVPENAQAGSSVFTFQALDGD 1426 Query: 716 -EGPNAVVHYSIKGGDDSNS-FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---- 769 GPN+ V Y++ + + F L++R G L LD E+ + LV+ A Sbjct: 1427 GVGPNSQVRYALLRQEPPGAPFHLDSRSGL----LSLHQSLDREAV-ASFLLVVEATDQA 1481 Query: 770 --ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVTD- 825 S + V + VTDVNDNAPV + + + P G V A D D+ + Sbjct: 1482 RNVSQRRSSAVTARVFVTDVNDNAPVFLSPAAV--SVTEDRPTGFVALHVVAQDNDLGEN 1539 Query: 826 -KLQYRILSGNNANLILLNETTGSMTLSPQLN 856 ++ Y + +GN LN +TG++++ LN Sbjct: 1540 GRVSYSLRAGNGDGRFHLNPSTGALSVVRALN 1571 Score = 196 bits (479), Expect = 5e-48 Identities = 173/589 (29%), Positives = 264/589 (44%), Gaps = 39/589 (6%) Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325 + E P G I + A G +A + Y ++ ++ +G V + ID G + T+ LD Sbjct: 28 IDEEQPAGTIIGDISA-GLPPGTSAYM-YFISAQEGSG-VTTDLWIDENRGIIKTARVLD 84 Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 RET+ Y + P T F ++ E P G+ Sbjct: 85 RETRDHYSFIAVT------PEGITVEVNIQVNDINDHAPAFPKQHSTFQIPEHTPVGSRF 138 Query: 386 VTLTATDADED--NRLHYEITGGNTRGRFSITSQNG-RGL----ITVAQPLDFKQERRYV 438 A DAD N Y I G N F + ++ G G+ + V+ LD + Y Sbjct: 139 PLDPAFDADSGLLNTQGYVIKGDNVGQAFRLETRRGPNGVLYLDLVVSNVLDRENRSSYS 198 Query: 439 LTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496 L + A D G RS + ++I D N+ AP F + Y + E+ G+++L V A+D+ Sbjct: 199 LVLEAYDGGTPPRSSQMTLDVSIQDINDNAPAFNQSRYHTLISENLKPGSSILQVFASDA 258 Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556 D G N + Y + N + DQ F I+ +TG I NK LD E + L V ARD Sbjct: 259 DEGDNGDVIYEI-----NRRQSDPDQYFTIDSRTGVIKLNKGLDYEVRKVHELVVQARDR 313 Query: 557 GVPSLSDTTDVEISVVDVNDNEP----VFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612 V T V I V D NDN+P +F + + I E A G V+++ +D D G Sbjct: 314 AVHPEVTTAFVTIHVRDYNDNQPTMTIIFLSEDGSPQISEGAQPGQYVARISVSDPDYGE 373 Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672 ++ L+ D + D +I ++ LDRE ++DL+ A D GTPP + Sbjct: 374 YSNVNVTLEGGDGKFALTTKDNIIYLICVDQLLDREERDSYDLRVTATDSGTPPLRAEST 433 Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732 +++ DIND+PP+F+ I E G+ + ++ A D D+GPN V YSI D+ Sbjct: 434 FVLQVIDINDNPPLFDQQEYKQSIPEVVYPGSFVLQVTARDKDQGPNGEVQYSIVHSHDT 493 Query: 733 NS--FSLETRQGSDKAELVTMVDLDYE-SPRKKYE-LVIRAASPPLWNDVRVEILVTDVN 788 +S F+++ G + T LDYE P+ + L +P L + V + + DVN Sbjct: 494 HSSWFAIDPATGI----ITTAAPLDYEKDPQPQLTVLATDRGTPALSSSAVVLVALQDVN 549 Query: 789 DNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDAD--VTDKLQYRILSG 834 DN PV + + K+ PVG F +V A DAD + L Y + SG Sbjct: 550 DNEPVFRS-NFYNVSLKENTPVGTCFLQVTATDADSGLFGSLSYSLGSG 597 Score = 41.9 bits (94), Expect = 0.25 Identities = 48/158 (30%), Positives = 68/158 (43%), Gaps = 14/158 (8%) Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY--SIKGGDDSNSFSLETRQGSDKAELV 749 L I E P GT IG+I A P G +A +++ + +G + ++ +G K V Sbjct: 24 LDLQIDEEQPAGTIIGDISAGLP-PGTSAYMYFISAQEGSGVTTDLWIDENRGIIKTARV 82 Query: 750 TMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809 LD E+ R Y + A P V V I V D+ND+AP F + P Sbjct: 83 ----LDRET-RDHYSFI---AVTPEGITVEVNIQVNDINDHAPAFPKQHSTF-QIPEHTP 133 Query: 810 VGP-FGRVPAYDADV-TDKLQYRILSGNNANLILLNET 845 VG F PA+DAD Q ++ G+N ET Sbjct: 134 VGSRFPLDPAFDADSGLLNTQGYVIKGDNVGQAFRLET 171 >UniRef50_Q4S3T6 Cluster: Chromosome 20 SCAF14744, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 20 SCAF14744, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 2289 Score = 340 bits (835), Expect = 4e-91 Identities = 268/892 (30%), Positives = 428/892 (47%), Gaps = 73/892 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I + D ND+ PVFE ++A + E S VL + A D D G N ++EY+I D Sbjct: 329 EITIQDVNDNYPVFEKDPFQADILENLSP-QRVLVVSAVDLDSGPNGQLEYSI----VDG 383 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N E++ F I+ +G + T LDREKVA+Y++ VKATD P + Sbjct: 384 -NKENS--------------FSINRATGEIRTTRPLDREKVAQYSLKVKATDWGLP---Q 425 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG--ANSAI 187 + + +NI+D NDN P+FS K ++ +V E+ V + ++ TD D G AN Sbjct: 426 KNMAVKVLINILDVNDNAPRFS-KIFSATVAENAPV--GYTVTRVTTTDEDAGSNANECQ 482 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 + I ++F +S +G ++ + + ++ A D + T +++NI Sbjct: 483 HWGDI-CKQPLKFQ-NSTAGSLN---------INRHSFIVTASDRAVQPLMSETTVIVNI 531 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYD-ADEGVNAELTYTMTDKDYTGNVD 306 D NDN P+F + + V+++V +G + RV A+D D G+N+E+ Y +T GN Sbjct: 532 VDSNDNPPQFESPNYFTPVAKSVKVGTRLTRVVAHDKKDFGLNSEVEYVITG----GNSS 587 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 +D SGW+ + L + + + +TATD G+PP S + F Sbjct: 588 SKFQLDKSSGWITVASSLISDVNKIFMVGITATDRGNPPLSGLTSLRIAVTEENHHTPEF 647 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLIT 424 Q + E GT + TL+A D D+D + Y IT GN RG FSI S++ G+++ Sbjct: 648 SQSQVSATIPESLAVGTAIRTLSARDKDKDMNGVITYNITSGNDRGLFSINSRS--GVLS 705 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ--INITDANNYAPVFENAPYTASVFEDA 482 +A PLDF++++++ L VSA D G + T+ V +++TD N+ PVFE Y V E+ Sbjct: 706 LAGPLDFEEKQQHNLRVSAIDGGWIAKTSYVSVTVHVTDVNDNPPVFEPDEYFPVVQENV 765 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 P GTTV+ ++A D D G NA + Y + S S+ FVI+P TG ITT LD E Sbjct: 766 PSGTTVVKMNAKDGDSGANAVMAYVIQSSDSD--------LFVIDPNTGTITTQGFLDYE 817 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 Y LTV A + +V I + N+ P F + Y + E A GT V + Sbjct: 818 AKQVYHLTVKAFNVPDEERCSLANVNIQLKGANEYVPRFVSKQYYFEVSEAAPKGTVVGE 877 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 V A+D D G NG ++Y + K R++G F I+ +G I ALDRE LK +A + Sbjct: 878 VFASDRDQGDNGVVYYLIFGKSRKKG-FGINETTGQIYVTGALDREKEEKISLKVLAKNA 936 Query: 663 GT--PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN- 719 G+ V V+I + D ND PPVF + +SE G + + A D D P+ Sbjct: 937 GSIRGADIDEVFVNITVLDAND-PPVFTQELYDVQVSEGLSPGGLVTFVSAEDSDSVPSW 995 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR 779 + YSI D F++ T+ G + + +D + L + +PP Sbjct: 996 SRFSYSIAPESDQKVFTINTKTG--QVSVAAPLDRERTPVYNLTVLAVDTGTPPATGSAT 1053 Query: 780 VEILVTDVNDNAPVM-KDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK---LQYRILSGN 835 V + + D+NDN P + + + N + V + A DAD+ + +LS Sbjct: 1054 VIVNLEDINDNGPTLTTSYAEVMENQRAGTAV---TTLTASDADLPPNRGPFLFSLLSSG 1110 Query: 836 NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRL 886 +AN +G++T S +++ + V + D GV ++ + + V++ Sbjct: 1111 SANSYFSLSQSGALTTSREIDREQISDFYLSVVIKDAGVPQMSSTGTIHVKV 1162 Score = 320 bits (787), Expect = 3e-85 Identities = 280/1009 (27%), Positives = 450/1009 (44%), Gaps = 70/1009 (6%) Query: 110 VARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP 169 + R++ +V A+D+A V +S T T+ VNI+D NDN PQF Y V + + V Sbjct: 504 INRHSFIVTASDRA--VQPLMSET-TVIVNIVDSNDNPPQFESPNYFTPVAKSVKVGTR- 559 Query: 170 VIAKIKATDA-DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIR 228 + ++ A D D G NS + Y I GGN+ +F +D SG +++ +L + + + + I Sbjct: 560 -LTRVVAHDKKDFGLNSEVEYVITGGNSSSKFQLDKSSGWITVASSLISDVNKIFMVGIT 618 Query: 229 AQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV 288 A D G+P S T L I + + N + P F S ++ E++ +G +I + A D D+ + Sbjct: 619 ATDRGNPPLSGLTSLRIAVTEENHHTPEFSQSQVSATIPESLAVGTAIRTLSARDKDKDM 678 Query: 289 NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348 N +TY +T +GN +I+ RSG + +G LD E + ++ L V+A DGG +++ Sbjct: 679 NGVITYNIT----SGNDRGLFSINSRSGVLSLAGPLDFEEKQQHNLRVSAIDGGWIAKTS 734 Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGN 407 + F P +Y + E+ P GT VV + A D D N + + + Sbjct: 735 YVSVTVHVTDVNDNPPVFEPDEYFPVVQENVPSGTTVVKMNAKDGDSGANAVMAYVIQSS 794 Query: 408 TRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA--TDSGGRSDTAMVQINITDANNY 465 F I G IT LD++ ++ Y LTV A R A V I + AN Y Sbjct: 795 DSDLFVIDPNT--GTITTQGFLDYEAKQVYHLTVKAFNVPDEERCSLANVNIQLKGANEY 852 Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525 P F + Y V E AP GT V V A+D D G N + Y + + + F Sbjct: 853 VPRFVSKQYYFEVSEAAPKGTVVGEVFASDRDQGDNGVVYYLIFGKSRKKG-------FG 905 Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD--VEISVVDVNDNEPVFKQ 583 IN TG I LDRE L V A++ G +D + V I+V+D ND PVF Q Sbjct: 906 INETTGQIYVTGALDREKEEKISLKVLAKNAGSIRGADIDEVFVNITVLDAND-PPVFTQ 964 Query: 584 QLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642 +LY + E G V+ V A D+D V R Y + P + ++ F I+ +G + Sbjct: 965 ELYDVQVSEGLSPGGLVTFVSAEDSDSVPSWSRFSYSIAP-ESDQKVFTINTKTGQVSVA 1023 Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 LDRE ++L +A+D GTPP + + V + +EDIND+ P + + EN Sbjct: 1024 APLDRERTPVYNLTVLAVDTGTPPATGSATVIVNLEDINDNGPTLTTSYAE--VMENQRA 1081 Query: 703 GTTIGEIRAHDPDEGPN-AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761 GT + + A D D PN +S+ +NS+ ++ G+ L T ++D E Sbjct: 1082 GTAVTTLTASDADLPPNRGPFLFSLLSSGSANSYFSLSQSGA----LTTSREIDREQISD 1137 Query: 762 KY-ELVIRAASPPLWNDV-RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY 819 Y +VI+ A P + + + V D NDN + +I + + + FP G G V Sbjct: 1138 FYLSVVIKDAGVPQMSSTGTIHVKVNDQNDNPSEPRAVEIFVHYFGNMFPGGLLGDVKPQ 1197 Query: 820 DADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSV--TDGVN-EI 876 D D+ D+ ++ ++ + + TG+ L+ + + T E+++ +DGV+ + Sbjct: 1198 DPDIQDRFHCSLIPPSSG---IFSIPTGTCNLNSKARSTD---GTFEITIRSSDGVHGSV 1251 Query: 877 KAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSV 936 + ++ T + NSI +RL + FL+ ++ L N + + Sbjct: 1252 SSTARVLFMGFTNATVDNSILIRLQSQGVKSFLT---NHYLSFLRI------ANSKLAGL 1302 Query: 937 QDDTDVTGNILNVSFSARRPD-AEVGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVL 995 TG +L +F V + +P+ + + L R + VQ+ Sbjct: 1303 G-----TGVLLYGAFELNNQTFLMAAVKRSHGQYVNPSGVATFFQSIKDILYRQSGVQID 1357 Query: 996 PFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNC 1055 D + C H PC N C L G S V+ P+ + C C G+TG C Sbjct: 1358 AVDYDPCTHNPCQNGGSCKRRLGVGPDMRSEESVPVILVFSRPLQPYACSCRPGYTGALC 1417 Query: 1056 ETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCE 1104 ET + + C+ S C +G C GG C+ +T CE Sbjct: 1418 ETDINE--CQ----PSPCHNGGTC-HNLVGGF---SCTCPEGFTGMACE 1456 Score = 304 bits (747), Expect = 2e-80 Identities = 226/715 (31%), Positives = 349/715 (48%), Gaps = 53/715 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQ-DIGKNAEVEYTIELVTADT 69 +N++D ND+ P FE Y V + GT + + A D+ D G N+EVEY I T Sbjct: 529 VNIVDSNDNPPQFESPNYFTPVAKSVKVGTRLTRVVAHDKKDFGLNSEVEYVI---TGGN 585 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + + F++D SG + +SL + + V + ATD+ +P Sbjct: 586 SSSK----------------FQLDKSSGWITVASSLISDVNKIFMVGITATDRGNPP--- 626 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LS ++ + + ++N + P+FS+ + ++ E ++V I + A D D N I Y Sbjct: 627 LSGLTSLRIAVTEENHHTPEFSQSQVSATIPESLAV--GTAIRTLSARDKDKDMNGVITY 684 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I GN + FSI+S SG +SL LD+E+ + + L + A DGG ++++ + +++ D Sbjct: 685 NITSGNDRGLFSINSRSGVLSLAGPLDFEEKQQHNLRVSAIDGGWIAKTSYVSVTVHVTD 744 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 VNDN P F + V ENVP G ++V++ A D D G NA + Y + D DL Sbjct: 745 VNDNPPVFEPDEYFPVVQENVPSGTTVVKMNAKDGDSGANAVMAYVIQSSD----SDL-F 799 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 IDP +G + T G LD E + Y L V A + D R + A F+ Sbjct: 800 VIDPNTGTITTQGFLDYEAKQVYHLTVKAFNVPDEERCSLANVNIQLKGANEYVPRFVSK 859 Query: 370 QYEVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGR-FSITSQNGRGLITVAQ 427 QY E++E P GT V + A+D D+ DN + Y + G +R + F I G+ +T A Sbjct: 860 QYYFEVSEAAPKGTVVGEVFASDRDQGDNGVVYYLIFGKSRKKGFGINETTGQIYVTGA- 918 Query: 428 PLDFKQERRYVLTVSATDS----GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 LD ++E + L V A ++ G D V I + DAN+ PVF Y V E Sbjct: 919 -LDREKEEKISLKVLAKNAGSIRGADIDEVFVNITVLDAND-PPVFTQELYDVQVSEGLS 976 Query: 484 IGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 G V VSA DSD V ++ +YS++ E S++ V F IN +TG ++ LDRE Sbjct: 977 PGGLVTFVSAEDSDSVPSWSRFSYSIAPE-SDQKV------FTINTKTGQVSVAAPLDRE 1029 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 Y LTV A D G P + + V +++ D+NDN P A +ME+ GT+V+ Sbjct: 1030 RTPVYNLTVLAVDTGTPPATGSATVIVNLEDINDNGPTLTTSY--AEVMENQRAGTAVTT 1087 Query: 603 VGATDADVGLN-GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 + A+DAD+ N G + L F + SG + T++ +DRE ++ L V D Sbjct: 1088 LTASDADLPPNRGPFLFSLLSSGSANSYFSLS-QSGALTTSREIDREQISDFYLSVVIKD 1146 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFES-DCLTFYISENSPIGTTIGEIRAHDPD 715 G P SST +H+K+ D ND+P + + Y P G +G+++ DPD Sbjct: 1147 AGVPQMSSTGTIHVKVNDQNDNPSEPRAVEIFVHYFGNMFP-GGLLGDVKPQDPD 1200 Score = 299 bits (735), Expect = 5e-79 Identities = 251/867 (28%), Positives = 396/867 (45%), Gaps = 72/867 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D ND+ P F Y + ++G+ V + TD+D G NA++ Y++ Sbjct: 127 VTVADINDNPPRFHHHPYVTHIPASTAAGSLVFAVTVTDEDAGSNAQLHYSL-------- 178 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F+ID GA+ L TV VK A+P +D Sbjct: 179 ------------IGRSSEKFKIDPIRGAITANEKLTGSSEVTLTVRVK-DGGANPKTDM- 224 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 T+ V + ++P K + E S N ++ + + G S Y Sbjct: 225 ---TTVTVRFVTGG-SFPVIKLKERAFTFPE--SQPANHIVTTVTGSSMRGGPLS---YY 275 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I GN F ID LSG++S+ LDYE ++ Y L I A+D G P S+ ++ I I+DV Sbjct: 276 IASGNLDHAFHIDQLSGELSIRHPLDYEHIQKYVLWIEARDQGFPPYSSYEKVEITIQDV 335 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F FQ + EN+ ++ V A D D G N +L Y++ D GN + + Sbjct: 336 NDNYPVFEKDPFQADILENLS-PQRVLVVSAVDLDSGPNGQLEYSIVD----GNKENSFS 390 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I+ +G + T+ LDRE A+Y L V ATD G P ++ F Sbjct: 391 INRATGEIRTTRPLDREKVAQYSLKVKATDWGLPQKNMAVKVLINILDVNDNAPRFSK-I 449 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 + +AE+ P G V +T TD D + + E + + QN + A L+ Sbjct: 450 FSATVAENAPVGYTVTRVTTTDEDAGSNAN-ECQHWGDICKQPLKFQN-----STAGSLN 503 Query: 431 FKQERRYVLTVSATDSGGR---SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 R+ V+A+D + S+T ++ +NI D+N+ P FE+ Y V + +GT Sbjct: 504 I---NRHSFIVTASDRAVQPLMSETTVI-VNIVDSNDNPPQFESPNYFTPVAKSVKVGTR 559 Query: 488 VLVVSATD-SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 + V A D D G+N+++ Y ++ + +F ++ +G IT L + Sbjct: 560 LTRVVAHDKKDFGLNSEVEYVITG-------GNSSSKFQLDKSSGWITVASSLISDVNKI 612 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 +++ +TA D G P LS T + I+V + N + P F Q +A I E VGT++ + A Sbjct: 613 FMVGITATDRGNPPLSGLTSLRIAVTEENHHTPEFSQSQVSATIPESLAVGTAIRTLSAR 672 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D D +NG I Y + + G F I+ SGV+ LD E H+L+ AIDGG Sbjct: 673 DKDKDMNGVITYNI-TSGNDRGLFSINSRSGVLSLAGPLDFEEKQQHNLRVSAIDGGWIA 731 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 ++S V V + + D+ND+PPVFE D + EN P GTT+ ++ A D D G NAV+ Y I Sbjct: 732 KTSYVSVTVHVTDVNDNPPVFEPDEYFPVVQENVPSGTTVVKMNAKDGDSGANAVMAYVI 791 Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP---LWNDVRVEIL 783 + DS+ F ++ G+ + T LDYE+ ++ Y L ++A + P + V I Sbjct: 792 Q-SSDSDLFVIDPNTGT----ITTQGFLDYEA-KQVYHLTVKAFNVPDEERCSLANVNIQ 845 Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADVTDK--LQYRILSGNNANLI 840 + N+ P Q F + P G G V A D D D + Y I + Sbjct: 846 LKGANEYVPRFVSKQYYF-EVSEAAPKGTVVGEVFASDRDQGDNGVVYYLIFGKSRKKGF 904 Query: 841 LLNETTGSMTLSPQLNTNVPKLATMEV 867 +NETTG + ++ L+ + +++V Sbjct: 905 GINETTGQIYVTGALDREKEEKISLKV 931 Score = 292 bits (717), Expect = 8e-77 Identities = 226/753 (30%), Positives = 348/753 (46%), Gaps = 50/753 (6%) Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LS T + V + D NDN P FS T+ ++ ED + T V+ + ++DADVG N I Y Sbjct: 15 LSGTCMVTVFVSDVNDNAPVFSTSTFHTTITED-APTGTDVLL-VNSSDADVGNNGVISY 72 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR-SNTTQLLINIR 248 ++ GG+ Q FSI+ +G + LD E+ +Y+L++ A DGG P S++ + + + Sbjct: 73 SLSGGHGQ--FSINPATGQIITSSVLDREERANYQLLVVATDGGQPQGLSSSATVSVTVA 130 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D+NDN PRF+ + + + G + V D D G NA+L Y++ G Sbjct: 131 DINDNPPRFHHHPYVTHIPASTAAGSLVFAVTVTDEDAGSNAQLHYSL-----IGRSSEK 185 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 IDP G + + +L ++ L V DGG P++ T + Sbjct: 186 FKIDPIRGAITANEKLTGSSEV--TLTVRVKDGGANPKTDMTTVTVRFVTGGSFPVIKLK 243 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 + E +P V T+T + L Y I GN F I +G +++ P Sbjct: 244 -ERAFTFPESQPANHIVTTVTGSSM-RGGPLSYYIASGNLDHAFHIDQLSGE--LSIRHP 299 Query: 429 LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD++ ++YVL + A D G S V+I I D N+ PVFE P+ A + E+ Sbjct: 300 LDYEHIQKYVLWIEARDQGFPPYSSYEKVEITIQDVNDNYPVFEKDPFQADILENLS-PQ 358 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 VLVVSA D D G N Q+ YS+ + + F IN TG I T + LDRE ++ Sbjct: 359 RVLVVSAVDLDSGPNGQLEYSIVD-------GNKENSFSINRATGEIRTTRPLDREKVAQ 411 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y L V A D G+P + V I+++DVNDN P F ++++A + E+A VG +V++V T Sbjct: 412 YSLKVKATDWGLPQKNMAVKVLINILDVNDNAPRF-SKIFSATVAENAPVGYTVTRVTTT 470 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D D G N + + G P T +L ++ H A D P Sbjct: 471 DEDAGSNAN-------ECQHWGDICKQPLKFQNSTAGSL---NINRHSFIVTASDRAVQP 520 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD-PDEGPNAVVHYS 725 S V + I D ND+PP FES ++++ +GT + + AHD D G N+ V Y Sbjct: 521 LMSETTVIVNIVDSNDNPPQFESPNYFTPVAKSVKVGTRLTRVVAHDKKDFGLNSEVEYV 580 Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEI 782 I GG+ S+ F L+ G +T+ K + + I A +PPL + I Sbjct: 581 ITGGNSSSKFQLDKSSG-----WITVASSLISDVNKIFMVGITATDRGNPPLSGLTSLRI 635 Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA---YDADVTDKLQYRILSGNNANL 839 VT+ N + P Q + + VG R + D D+ + Y I SGN+ L Sbjct: 636 AVTEENHHTPEFSQSQ-VSATIPESLAVGTAIRTLSARDKDKDMNGVITYNITSGNDRGL 694 Query: 840 ILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 +N +G ++L+ L+ + + VS DG Sbjct: 695 FSINSRSGVLSLAGPLDFEEKQQHNLRVSAIDG 727 Score = 282 bits (691), Expect = 1e-73 Identities = 238/849 (28%), Positives = 385/849 (45%), Gaps = 75/849 (8%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72 V D ND++PVF + ++ E A +GT VL + ++D D+G N + Y++ Sbjct: 25 VSDVNDNAPVFSTSTFHTTITEDAPTGTDVLLVNSSDADVGNNGVISYSLS--------- 75 Query: 73 EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132 F I+ +G ++T + LDRE+ A Y +LV ATD P LSS Sbjct: 76 ------------GGHGQFSINPATGQIITSSVLDREERANYQLLVVATDGGQP--QGLSS 121 Query: 133 TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192 +AT+ V + D NDN P+F Y + S ++ + TD D G+N+ + Y++I Sbjct: 122 SATVSVTVADINDNPPRFHHHPYVTHI--PASTAAGSLVFAVTVTDEDAGSNAQLHYSLI 179 Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252 G +++ +F ID + G ++ + L L +R +DGG+ +++ T + +R V Sbjct: 180 GRSSE-KFKIDPIRGAITANEKLTGSS--EVTLTVRVKDGGANPKTDMT--TVTVRFVTG 234 Query: 253 NA-PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311 + P + E+ P + + V G L+Y + +GN+D I Sbjct: 235 GSFPVIKLKERAFTFPESQPANHIVTTVTGSSMRGG---PLSYYIA----SGNLDHAFHI 287 Query: 312 DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371 D SG + LD E KY L + A D G PP S+ F + Sbjct: 288 DQLSGELSIRHPLDYEHIQKYVLWIEARDQGFPPYSSYEKVEITIQDVNDNYPVFEKDPF 347 Query: 372 EVELAED-EPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 + ++ E+ P VV+ D+ + +L Y I GN FSI G I +PLD Sbjct: 348 QADILENLSPQRVLVVSAVDLDSGPNGQLEYSIVDGNKENSFSINRATGE--IRTTRPLD 405 Query: 431 FKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 ++ +Y L V ATD G ++ V INI D N+ AP F ++A+V E+AP+G TV Sbjct: 406 REKVAQYSLKVKATDWGLPQKNMAVKVLINILDVNDNAPRFSKI-FSATVAENAPVGYTV 464 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 V+ TD D G NA +I + + N G++ N+ + Sbjct: 465 TRVTTTDEDAGSNANECQHW-GDICKQPLKFQ------NSTAGSLNINR---------HS 508 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD- 607 VTA D V L T V +++VD NDN P F+ Y + + VGT +++V A D Sbjct: 509 FIVTASDRAVQPLMSETTVIVNIVDSNDNPPQFESPNYFTPVAKSVKVGTRLTRVVAHDK 568 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 D GLN + Y + F +D +SG I +L + + A D G PP Sbjct: 569 KDFGLNSEVEYVI-TGGNSSSKFQLDKSSGWITVASSLISDVNKIFMVGITATDRGNPPL 627 Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 S + I + + N P F ++ I E+ +GT I + A D D+ N V+ Y+I Sbjct: 628 SGLTSLRIAVTEENHHTPEFSQSQVSATIPESLAVGTAIRTLSARDKDKDMNGVITYNIT 687 Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW----NDVRVEIL 783 G+D FS+ +R G L LD+E ++++ L + A W + V V + Sbjct: 688 SGNDRGLFSINSRSG----VLSLAGPLDFEE-KQQHNLRVSAIDGG-WIAKTSYVSVTVH 741 Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADV-TDKLQYRILSGNNANLIL 841 VTDVNDN PV + + F ++ P G ++ A D D + + ++ ++++L + Sbjct: 742 VTDVNDNPPVFEPDE-YFPVVQENVPSGTTVVKMNAKDGDSGANAVMAYVIQSSDSDLFV 800 Query: 842 LNETTGSMT 850 ++ TG++T Sbjct: 801 IDPNTGTIT 809 Score = 252 bits (618), Expect = 8e-65 Identities = 206/670 (30%), Positives = 325/670 (48%), Gaps = 52/670 (7%) Query: 233 GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292 G PS S T + + + DVNDNAP F TS F +++E+ P G ++ V + DAD G N + Sbjct: 11 GVPSLSGTCMVTVFVSDVNDNAPVFSTSTFHTTITEDAPTGTDVLLVNSSDADVGNNGVI 70 Query: 293 TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP-RSATAT 351 +Y+++ G+ +I+P +G + TS LDRE +A YQLLV ATDGG P S++AT Sbjct: 71 SYSLSG----GHGQ--FSINPATGQIITSSVLDREERANYQLLVVATDGGQPQGLSSSAT 124 Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV--VTLTATDADEDNRLHYEITGGNTR 409 F Y + G+ V VT+T DA + +LHY + G ++ Sbjct: 125 VSVTVADINDNPPRFHHHPYVTHIPASTAAGSLVFAVTVTDEDAGSNAQLHYSLIGRSSE 184 Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYA-PV 468 +F I RG IT + L E LTV D G T M + + + PV Sbjct: 185 -KFKIDPI--RGAITANEKLTGSSE--VTLTVRVKDGGANPKTDMTTVTVRFVTGGSFPV 239 Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528 + + E P V V+ + G ++Y ++S + D F I+ Sbjct: 240 IKLKERAFTFPESQPANHIVTTVTGSSMRGG---PLSYYIAS-------GNLDHAFHIDQ 289 Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588 +G ++ LD E + Y+L + ARD G P S VEI++ DVNDN PVF++ + A Sbjct: 290 LSGELSIRHPLDYEHIQKYVLWIEARDQGFPPYSSYEKVEITIQDVNDNYPVFEKDPFQA 349 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648 +I+E+ L V V A D D G NG++ Y + +E SF I+ A+G IRT + LDRE Sbjct: 350 DILEN-LSPQRVLVVSAVDLDSGPNGQLEYSI-VDGNKENSFSINRATGEIRTTRPLDRE 407 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 VA + LK A D G P ++ V V I I D+ND+ P F S + ++EN+P+G T+ Sbjct: 408 KVAQYSLKVKATDWGLPQKNMAVKVLINILDVNDNAPRF-SKIFSATVAENAPVGYTVTR 466 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768 + D D G NA ++ + +Q K + T L+ ++ ++ Sbjct: 467 VTTTDEDAGSNA---------NECQHWGDICKQPL-KFQNSTAGSLNI----NRHSFIVT 512 Query: 769 A---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDA--- 821 A A PL ++ V + + D NDN P + F VG RV A+D Sbjct: 513 ASDRAVQPLMSETTVIVNIVDSNDNPPQFES-PNYFTPVAKSVKVGTRLTRVVAHDKKDF 571 Query: 822 DVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMM 880 + +++Y I GN+++ L++++G +T++ L ++V K+ + ++ TD G + + Sbjct: 572 GLNSEVEYVITGGNSSSKFQLDKSSGWITVASSLISDVNKIFMVGITATDRGNPPLSGLT 631 Query: 881 QLSVRLITEE 890 L + +TEE Sbjct: 632 SLRI-AVTEE 640 Score = 58.8 bits (136), Expect = 2e-06 Identities = 67/280 (23%), Positives = 104/280 (37%), Gaps = 30/280 (10%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPL 1369 C + C PC+NG C + D Y C C +D + P G + P Sbjct: 1493 CDSIINHCECNPCFNGGSCQNRVDGYYCHCP--FDVRDWKEPAPPAPADTGAPAWTTGPG 1550 Query: 1370 LRPIQLPWLNALSIRT-RQRDAFVMSIQLKSGLLHYSYNGETMYLPMATLSDGAWHRIEI 1428 L A S+R R + + +S G + + + A LSDG WH +++ Sbjct: 1551 SSASAWTALPADSVRNLRNGNIYYISDVGVLGKVERT-------IVDALLSDGQWHTLQL 1603 Query: 1429 KWLGTDISVTVDYGLRTVLMPMLANKIQGQYIGKILIGGLDTTAGLLASDVGFFEGCI-- 1486 G+ + VD G V+ G + + +GG+ + G F+GC+ Sbjct: 1604 VKNGSTTLLQVDDGHSRVIQ-HTTQDFGGLGVLTVSLGGIPPGPAQQKTAAG-FDGCLAY 1661 Query: 1487 -----QDVRIGTAQSLLNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEA 1541 +++ SL+ +V+ GC+ C + C CV W + C Sbjct: 1662 LKYNGENLPFAGEHSLVTLTKTSSSVKIGCRGPNLCESNPCWDSLMCVNQWYTYQC---- 1717 Query: 1542 GRVGPQCVSACELGPC-GAARCVPDQTPKGYSCACEPGYT 1580 V P C PC CVPD G++CAC YT Sbjct: 1718 --VPP---GDCASNPCQNQGSCVPD-PHSGFTCACSEFYT 1751 Score = 50.8 bits (116), Expect = 5e-04 Identities = 68/324 (20%), Positives = 110/324 (33%), Gaps = 21/324 (6%) Query: 1039 VTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRS---GSQCVARRE-GGILCQG--- 1091 V F+C CPEGFTG+ CE + + +G++C++ G C+ + G C Sbjct: 1439 VGGFSCTCPEGFTGMACERDVNECLSNPCKNGALCQNFPGGFNCLCKSGFSGKTCDSIIN 1498 Query: 1092 -CSIDAAYTTAVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNE 1150 C + + C+ R + K A T G + Sbjct: 1499 HCECNPCFNGGSCQNRVDGYYCHCPFDVRDWKE------PAPPAPADTGAPAWTTGPGSS 1552 Query: 1151 RHDFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITM 1210 + AL S R G + G V+ + DG WHT+++ T + Sbjct: 1553 ASAWTALPADSVRNLRNGNIYYISDVGVLGKVERTIVDALLSDGQWHTLQLVKNGSTTLL 1612 Query: 1211 ILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPT----ETCHRFLDLTGP-LQIG 1265 +DD + DFG + P + T + C +L G L Sbjct: 1613 QVDDGHSRVIQHTTQDFGGLGVLTVSLGGIPPGPAQQKTAAGFDGCLAYLKYNGENLPFA 1672 Query: 1266 GLPNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNG 1325 G ++ + + + +GC + +S + N C+S PC N Sbjct: 1673 GEHSLVTLTKTSSSVKIGCRGPNLCESNPC-WDSLMCVNQWYTYQCVPPGDCASNPCQNQ 1731 Query: 1326 AEC-SDLWDTYICDCKEGHTGKDC 1348 C D + C C E +TGK C Sbjct: 1732 GSCVPDPHSGFTCACSEFYTGKSC 1755 Score = 41.9 bits (94), Expect = 0.25 Identities = 17/43 (39%), Positives = 22/43 (51%) Query: 1306 TLAGCPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 T A C + C +PC+NG C +L + C C EG TG C Sbjct: 1413 TGALCETDINECQPSPCHNGGTCHNLVGGFSCTCPEGFTGMAC 1455 Score = 41.5 bits (93), Expect = 0.32 Identities = 38/162 (23%), Positives = 59/162 (36%), Gaps = 16/162 (9%) Query: 1533 DSSTCTCEAGRVGPQCVSACELGP-CGAARCVP-----DQTPKGYSCACEPGYT--LTTS 1584 D CT + G C +GP + VP + + Y+C+C PGYT L + Sbjct: 1360 DYDPCTHNPCQNGGSCKRRLGVGPDMRSEESVPVILVFSRPLQPYACSCRPGYTGALCET 1419 Query: 1585 GCIESGKEECPGGWWGGSACGPCACDVTRGY-HPHCNKENGKCHCKENHYKPEGTAECLP 1643 E C G + G +C G+ C ++ + C N K + P Sbjct: 1420 DINECQPSPCHNGGTCHNLVGGFSCTCPEGFTGMACERDVNE--CLSNPCKNGALCQNFP 1477 Query: 1644 ----CQCYAAGSENSSCEAATGQCHCRPGVIGRACDACANAY 1681 C C +G +C++ C C P G +C + Y Sbjct: 1478 GGFNCLC-KSGFSGKTCDSIINHCECNPCFNGGSCQNRVDGY 1518 Score = 40.7 bits (91), Expect = 0.57 Identities = 34/108 (31%), Positives = 44/108 (40%), Gaps = 12/108 (11%) Query: 1516 DCMLSICPPYSKCVTSWDSSTCTCEAGRVGPQC---VSACELGPC-GAARCVPDQTPKGY 1571 +C S C C +CTC G G C V+ C PC A C P G+ Sbjct: 1423 ECQPSPCHNGGTCHNLVGGFSCTCPEGFTGMACERDVNECLSNPCKNGALC--QNFPGGF 1480 Query: 1572 SCACEPGYTLTTSGCIESGKEECPGGWWGGSACGPCACDVTRGYHPHC 1619 +C C+ G++ T I EC + GGS C V GY+ HC Sbjct: 1481 NCLCKSGFSGKTCDSI-INHCECNPCFNGGS----CQNRVD-GYYCHC 1522 >UniRef50_P33450 Cluster: Cadherin-related tumor suppressor precursor; n=6; Coelomata|Rep: Cadherin-related tumor suppressor precursor - Drosophila melanogaster (Fruit fly) Length = 5147 Score = 340 bits (835), Expect = 4e-91 Identities = 294/1059 (27%), Positives = 478/1059 (45%), Gaps = 63/1059 (5%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDI-GKNAEVEYTIELVTADT 69 I + D ND++P FE Y S E S V + ATD+D G N+ + Y+++ Sbjct: 3001 ITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQIIATDRDKQGPNSVISYSLQ------ 3054 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 P +VF + + R Y + V ATD P Sbjct: 3055 -QPSPMFSIDPATG----EVF---SKKAVRFKHSQYVRSPENMYALTVLATDNGKPP--- 3103 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA-DVGANSAIR 188 L S +++NI+D ++N P+F + Y + +D I ++ A D D+G N + Sbjct: 3104 LYSECLVNINIVDAHNNPPKFEQAEYLAPLPQD--AVRGQRIVRVHANDKQDLGTNE-MD 3160 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y+++ N FS+ G ++LVK + Y LV+RA D G P +S+ T+++I + Sbjct: 3161 YSLMTFNLSSIFSVGRHDGWITLVKPIQVPPNTRYELVVRATDRGVPPQSDETRVVIVVT 3220 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 N + PRF + +Q V EN P+G +I+ V A D D G N L Y+++ GN Sbjct: 3221 GENMDTPRFSVNSYQVIVPENEPVGSTILTVGATDDDTGPNGMLRYSISG----GNERQD 3276 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 ++D R+G + QLD + +Y L +T D G P S+ A F Sbjct: 3277 FSVDERTGGIVIQQQLDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVNDNPPVFNH 3336 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVA 426 +Y + E++P GT V A D D +HY F I +Q+ G I+ A Sbjct: 3337 KEYHCYIPENKPVGTFVFQAHAADKDSPKNAIIHYAFLPSGPDRHFFIMNQS-NGTISSA 3395 Query: 427 QPLDFKQERRYVLTVSATDSGGRSDT-AMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 D+++ R Y L + A + ++ A + +++ N + P F + V E + +G Sbjct: 3396 VSFDYEERRIYTLQIKAKNPDSSMESYANLYVHVLGVNEFYPQFLQPVFHFDVSETSAVG 3455 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 T V V ATD D G + ++ Y L + +D+ F I+ TG I + LDRET + Sbjct: 3456 TRVGAVQATDKDSGEDGRVYYLLVG-------SSNDKGFRIDTNTGLIYVARHLDRETQN 3508 Query: 546 GYLLTVTARDGGVPSLSDTTDVE--ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 +LTV A++ G +DT + + IS+ D ND P F + YT+ I E A VGT V+ V Sbjct: 3509 RVVLTVMAKNYGSIRGNDTDEAQVIISIQDGND-PPEFIKHYYTSTISEAAPVGTKVTTV 3567 Query: 604 GATDADVGL-NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 A D DV N + Y + + ++ SF ID +G I T LDRE +T++L AID Sbjct: 3568 KAIDKDVRTQNNQFSYSIINGNLKQ-SFKIDVQTGEISTASRLDREETSTYNLVIGAIDT 3626 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN-AV 721 G PPQ+ + VHI++ED+ND+ P F + L YISEN P GT+I + A DPD N Sbjct: 3627 GLPPQTGSATVHIELEDVNDNGPTFTPEGLNGYISENEPAGTSIMTLIASDPDLPRNGGP 3686 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781 Y + GG + S++ G ++ T D + + V + P + + Sbjct: 3687 FTYQLIGGKHKSWLSVDRNSGVVRS--TTSFDREMTPILEAIIEVEDSGKPKQKSQHLLT 3744 Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLI 840 I V D NDN + I + + P V D D+ + R L N A Sbjct: 3745 ITVLDQNDNPSTTRSLHIAVSLFNGDLPSNVKLADVRPNDIDIVGDYRCR-LQKNPAQSQ 3803 Query: 841 LLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN-EIKAMMQLSVRLITEEMLLNSITVR 899 L + L +T P + + DG + ++ + + ++ + E L NS+++ Sbjct: 3804 LQLAIPRACDLITTSHT-TPIASVFSYTGNDGKHGDVSSKVSVAFQSFNNETLANSVSIM 3862 Query: 900 LNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAE 959 + +MTA FL+ ++ + + + ++ + ++S+ + +GN N+ Sbjct: 3863 VRNMTAYHFLANHYRPILEMIKSRM-SNEDEVILYSLLEGG--SGNSTNLQLL------- 3912 Query: 960 VGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKF 1019 + V + + P +L ER+ R+ + L +V+ + + C N C ++ Sbjct: 3913 MAVRLAKTSYQQPKYLIERLREKRSAFSELLQKEVIVGYEPCSEPDVCENGGVCSATMRL 3972 Query: 1020 GNASGFVNSDS---VLFRPIYPVTSFTCQCPEGFTGVNC 1055 +A FV DS VL P V ++CQC GF+G C Sbjct: 3973 LDAHSFVIQDSPALVLSGP-RVVHDYSCQCTSGFSGEQC 4010 Score = 327 bits (803), Expect = 3e-87 Identities = 267/924 (28%), Positives = 445/924 (48%), Gaps = 71/924 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ V D ND++P F Y ++ EGAS GT + + D D G N +V Y++ Sbjct: 1265 KVIVTDVNDNAPEFLRAPYHVTISEGASEGTHITHVFTQDADEGLNGDVYYSLA------ 1318 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 +A F +D +G L LDRE + ++V A D A + Sbjct: 1319 -KGNEAGQ------------FNLDSATGQLSLGRRLDRESQEIHHLIVVAKDAA--LKHP 1363 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LSS A+I + ++D+NDN P+F++ + VSV E S T ++ + +A+DAD G NS + + Sbjct: 1364 LSSNASITIVVLDENDNAPEFTQSSSEVSVLET-SPTGTELM-RFRASDADQGVNSQVVF 1421 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 +I GN + F IDS++G + L K LDYE + SY L I A D G+PS S T + + D Sbjct: 1422 SISAGNRRDTFHIDSITGSLYLHKPLDYEDITSYTLNITASDCGTPSLSTTVLYNVLVVD 1481 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 NDN P F ++ + E +P+ IV V A D D G+N +++Y ++ ++ Sbjct: 1482 DNDNPPIFPSTAIVRQIKEGIPLKTPIVTVTADDPDSGLNGKVSYAISKQEPQLPQGRHF 1541 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX---F 366 I+ +G ++T ++DRE+ ++L V ATD P +T F Sbjct: 1542 GINTETGVIHTLREIDRESIDTFRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAPVF 1601 Query: 367 MPGQYEV---ELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRG 421 + + + + + T V+ + A DAD + + YEI G + F + Q G Sbjct: 1602 VSMNAAILPPKFSTSKGSSTAVMQVHAKDADSSSNGLVTYEIVSG-PQELFKL--QRNTG 1658 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT-------DANNYAPVFEN-AP 473 +IT FKQE RY LT+ +TD +S+ ++ IT + + P FE + Sbjct: 1659 IITFTPGPQFKQEVRYQLTLKSTDEAVQSERRSSEVYITIITPGSGGSESSVPQFEQRSK 1718 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 + SV+E+ PIGT++L V+A + +A+I Y +++ + + D+ F I+ + G + Sbjct: 1719 LSGSVYENEPIGTSILTVTAHLA----SAEIEYFVTNVTATGSRGQVDRLFDIDAKLGIL 1774 Query: 534 TTNKLLDRET-MSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 +T LDRE Y + V A GG P S T V ++V+D ND+ P F + N+ Sbjct: 1775 STAAELDREAGPEEYEVEVYAIALGGQPRTS-RTKVRVTVLDKNDSPPQFLDTPFVYNVS 1833 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA 651 ED +G ++S + A D D G + + L D +G F+++P++G + N LDRE+ + Sbjct: 1834 EDLQIGHTISTLRAHDPDT--LGSVTFLL--MDGHDGKFLLEPSTGKLILNDTLDRETKS 1889 Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711 ++L+ DG Q + I++ D ND+PP+FE +F I EN+ G +G+I A Sbjct: 1890 KYELRIRVSDG---VQYTEAYATIQVSDTNDNPPLFEDTVYSFDIPENAQRGYQVGQIVA 1946 Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA-- 769 D D G NA + Y + ++ FSL + G L LDYE + Y L+++A Sbjct: 1947 RDADLGQNAQLSYGVVSDWANDVFSLNPQTGM----LTLTARLDYEEVQH-YILIVQAQD 2001 Query: 770 -ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK-- 826 P L + V V D+NDNAP+ +++ V A D D + Sbjct: 2002 NGQPSLSTTITVYCNVLDLNDNAPIFDPMSYSSEVFENVPIATEVVTVSAKDIDSGNNGL 2061 Query: 827 LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886 ++Y I +G+ + + ++ G++ L+ T+ V+ D +E + +L Sbjct: 2062 IEYSITAGDVDSEFGI-DSNGTIRTRRNLDREHRSTYTLTVTARDCADEFASFSELE--- 2117 Query: 887 ITEEMLLNSITVRLNDMTAEQFLS 910 ++ L + R T ++FL+ Sbjct: 2118 -ETQLKLKYRSPRKYQQTRQEFLA 2140 Score = 325 bits (799), Expect = 9e-87 Identities = 276/939 (29%), Positives = 444/939 (47%), Gaps = 103/939 (10%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 H I+V D NDH PVFE +Y A + E A +G+ V ++ ATD+D G NA+V Y ++++ Sbjct: 479 HLIIDVNDVNDHEPVFEKSEYSAVLSELAPTGSFVASITATDEDTGVNAQVHY--DILSG 536 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 + L F +D +G ++T LDRE R TV + + + + Sbjct: 537 NELK-----------------WFSMDPLTGLIVTTGPLDRE--IRDTVELSISARDGGPN 577 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 + + T + V I+D+ND PQFS++ V++ ED ++A + ATD D G N ++ Sbjct: 578 PKFAYTQ-LKVIILDENDEAPQFSQREQNVTLGED--APPQTIVALMTATDHDQGTNGSV 634 Query: 188 RYAIIGGNTQM---QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQL 243 +A+ ++ QF++D+L+G ++ + LD E++ Y + + A+D G+P+ +S T + Sbjct: 635 TFALAPSVERLYPLQFALDALTGQLTTRRPLDREKMSQYEISVIARDQGAPTPQSATATV 694 Query: 244 LINIRDVNDNAPRFYTSLFQESVSEN---------VPIGYSIVRVQAYDADEGVNAELTY 294 +N+ DVNDN P+FY + S++++ V ++ V A D D+G NA + Y Sbjct: 695 WLNVADVNDNDPQFYPRHYIYSLADDDDDIKLKKEVEKERILLHVTASDKDDGDNALIEY 754 Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK--YQLLVTATDGGD--PPRSATA 350 + +G L +D RSG + G K Y+LLV+A D G + A Sbjct: 755 RLE----SGGEGL-FQLDARSGAISLRGDAPASMHWKPHYKLLVSARDAGQRRSQQDAIV 809 Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEP------PGTPV--VTLTATDADEDNRLHYE 402 G YE ++ ED P V V + +T+ ++ + Y+ Sbjct: 810 EIVLKSKLEMLECGQAQAGGYEFQMVEDHEQQRNSQPNREVGIVQVKSTNGKANSHIEYD 869 Query: 403 ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA--------M 454 I G+ F I +++GR IT A+PLD +++ Y LT+ A+ S S A + Sbjct: 870 IIQGDRAQNFRIDTRSGR--ITTARPLDREEQANYRLTILASSSSSSSAAASSVSYGQCI 927 Query: 455 VQINITDANNYAPVF----ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510 V I I D N+ APVF E+ P T S+ E+A +G + + D D G+N++I+YSL++ Sbjct: 928 VNIAIIDLNDNAPVFALDRESEP-TISLPENAAVGQEIYLSRVRDRDAGVNSRISYSLTN 986 Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570 + +QQF I P TG + + + E S + + A D G P LS + + Sbjct: 987 --------NPNQQFRIGPVTGVLYLQRPIRAEPGSLIHVELMATDAGSPPLSSKLSLSVL 1038 Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630 + DVND+ PVF Y ++ E V T + ATD D+G NGRI YE+ + E F Sbjct: 1039 IADVNDHTPVFDHTSYETSLPETTKVNTRFFALAATDIDLGDNGRISYEI-IEGNTERMF 1097 Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690 + P G + LDRE + L D G P +SS V V I + D ND+ P F + Sbjct: 1098 GVFP-DGYLFVRAPLDREERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQFTNS 1156 Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA---- 746 TF I EN+P T +G++ A D D G NA + +++ + F+++TR G K Sbjct: 1157 TFTFSIPENAPADTFVGKLTAVDRDIGRNAELSFTL--SSQTQDFTIDTRNGFIKTLRPF 1214 Query: 747 --ELVTMVDLDYE----------SPRKKYELVIRAAS----PPLWNDVRVEILVTDVNDN 790 E + V + E S Y L+ S P L + V+V+++VTDVNDN Sbjct: 1215 DREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDN 1274 Query: 791 APVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGS 848 AP + V DAD + + Y + GN A L+ TG Sbjct: 1275 APEFLRAPYHVTISEGASEGTHITHVFTQDADEGLNGDVYYSLAKGNEAGQFNLDSATGQ 1334 Query: 849 MTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887 ++L +L+ ++ + V D + S+ ++ Sbjct: 1335 LSLGRRLDRESQEIHHLIVVAKDAALKHPLSSNASITIV 1373 Score = 325 bits (799), Expect = 9e-87 Identities = 257/862 (29%), Positives = 414/862 (48%), Gaps = 71/862 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGA--SSGTTVLTLKATDQDIGK-NAEVEYTIELVTA 67 IN+LD ND+ P F Y A V E +G VLT+ A D D N++V Y ++ Sbjct: 2372 INILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLK--EG 2429 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 D+ D+FRI+ SG + LDRE+ + YT+ + A D SP Sbjct: 2430 DS------------------DLFRINASSGDIALLKPLDREQQSEYTLTLVAMDTGSP-- 2469 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 L+ T + V + D NDN P F ++Y +V E++ + +ATD D G N+ + Sbjct: 2470 -PLTGTGIVRVEVQDINDNDPVFELQSYHATVRENL--PSGTHVLTPRATDKDEGLNAKL 2526 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG-SPSRSNTTQLLIN 246 R+ ++G + +F IDS +G++S TLD E+ Y L + AQD + R+++ L I+ Sbjct: 2527 RFNLLGEHMH-RFHIDSETGEISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTIS 2585 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + DVNDN P+F ++ + +V E + G + +A D D+G NA + YT++ +D Sbjct: 2586 VSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALDLDDGENAVVHYTISGRD-----Q 2640 Query: 307 LPITIDPRSGWVYTSGQLDRETQA----KYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 I+ ++G V T +L +T++ Y ++++A D G+ S+ A Sbjct: 2641 HYFDINTKTGVVSTKLELKTKTKSHDDLTYTIVISAMDQGEQSLSSKAELTVILRPPELF 2700 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGR 420 ++ED PG + ++AT + ++ Y I GG S+ Sbjct: 2701 PTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRYAIAGGIMGD--SLRVDPNS 2758 Query: 421 GLITVAQP-LDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTAS 477 GL++V Q LD++ Y + + A D S ++ +N+TDAN+ APV E Y A Sbjct: 2759 GLLSVGQDGLDYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQLIYNAE 2818 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 V E+ + VV A+D D G N + Y L ++ D F I ++G I T Sbjct: 2819 VLEEESPPQLIAVVKASDRDSGDNGNVIYRLQNDF--------DGTFEIT-ESGEIYTRM 2869 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LDRE + Y V A D GVP ++ T V + ++D NDN P F +L++ N+ E+A +G Sbjct: 2870 RLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPKF-TRLFSLNVTENAEIG 2928 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 + V +V ++D D+G N Y E+ F I+P SG I LDRE + LK Sbjct: 2929 SFVIRVTSSDLDLGANANASYSFSENPGEK--FRIEPQSGNITVAGHLDREQQDEYILKV 2986 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-E 716 VA DG ++ + I I+D ND+ P FE +F E +G+I A D D + Sbjct: 2987 VASDGAWRAETP---ITITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQIIATDRDKQ 3043 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGS-DKAELVTMVDLDY-ESPRKKYELVIRA---AS 771 GPN+V+ YS++ S FS++ G + V Y SP Y L + A Sbjct: 3044 GPNSVISYSLQ--QPSPMFSIDPATGEVFSKKAVRFKHSQYVRSPENMYALTVLATDNGK 3101 Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD-ADV-TDKLQY 829 PPL+++ V I + D ++N P + + + +D RV A D D+ T+++ Y Sbjct: 3102 PPLYSECLVNINIVDAHNNPPKFEQAEYLAPLPQDAVRGQRIVRVHANDKQDLGTNEMDY 3161 Query: 830 RILSGNNANLILLNETTGSMTL 851 +++ N +++ + G +TL Sbjct: 3162 SLMTFNLSSIFSVGRHDGWITL 3183 Score = 314 bits (770), Expect = 3e-83 Identities = 241/796 (30%), Positives = 384/796 (48%), Gaps = 64/796 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I +LD ND+SPVF+ +QY ASV E AS G VL + ATD D G N + Y+I V D Sbjct: 2266 IRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGRIRYSI--VLGDQN 2323 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F I +G + +L+ E+++RY++ V+A D A + + Sbjct: 2324 HD-----------------FSISEDTGVVRVAKNLNYERLSRYSLTVRAEDCA--LENPA 2364 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA-NSAIRY 189 TA + +NI+D NDN P F + Y V E+ + + + A DAD NS +RY Sbjct: 2365 GDTAELTINILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRY 2424 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 + G++ + F I++ SGD++L+K LD EQ Y L + A D GSP + T + + ++D Sbjct: 2425 FLKEGDSDL-FRINASSGDIALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQD 2483 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 +NDN P F + +V EN+P G ++ +A D DEG+NA+L + + G Sbjct: 2484 INDNDPVFELQSYHATVRENLPSGTHVLTPRATDKDEGLNAKLRFNLL-----GEHMHRF 2538 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPPRSATATXXXXXXXXXXXXXXFMP 368 ID +G + T+ LDRE + Y L + A D PR+++ F Sbjct: 2539 HIDSETGEISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDS 2598 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVA 426 Y V + E G V A D D+ +HY I+G + F I ++ G V+ Sbjct: 2599 TTYNVAVPERISKGEFVFGARALDLDDGENAVVHYTISGRDQH-YFDINTKTG----VVS 2653 Query: 427 QPLDFKQERR------YVLTVSATDSGGRSDTAMVQIN-ITDANNYAPVFEN-APYTASV 478 L+ K + + Y + +SA D G +S ++ ++ I P F A ++ Sbjct: 2654 TKLELKTKTKSHDDLTYTIVISAMDQGEQSLSSKAELTVILRPPELFPTFAYMANSHFAM 2713 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 ED G + VSAT G+ +I Y+++ I +++ ++P +G ++ + Sbjct: 2714 SEDVRPGKMITKVSATSPKKGLVGKIRYAIAGGIMGDSLR-------VDPNSGLLSVGQD 2766 Query: 539 -LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LD E Y + + A DG PSL T + ++V D NDN PV +Q +Y A ++E+ Sbjct: 2767 GLDYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQLIYNAEVLEEESPP 2826 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 ++ V A+D D G NG + Y L ++ +G+F I SG I T LDRE + + Sbjct: 2827 QLIAVVKASDRDSGDNGNVIYRL--QNDFDGTFEI-TESGEIYTRMRLDREEIGDYAFVV 2883 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A+D G P + T V + + D ND+PP F + + ++EN+ IG+ + + + D D G Sbjct: 2884 EAVDQGVPHMTGTASVLLHLLDKNDNPPKF-TRLFSLNVTENAEIGSFVIRVTSSDLDLG 2942 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN- 776 NA YS + F +E + G+ + LD E + +Y L + AS W Sbjct: 2943 ANANASYSF-SENPGEKFRIEPQSGN----ITVAGHLDREQ-QDEYILKV-VASDGAWRA 2995 Query: 777 DVRVEILVTDVNDNAP 792 + + I + D NDNAP Sbjct: 2996 ETPITITIQDQNDNAP 3011 Score = 312 bits (766), Expect = 9e-83 Identities = 252/917 (27%), Positives = 415/917 (45%), Gaps = 88/917 (9%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72 + D NDH+PVF+ YE S+ E T L ATD D+G N + Y E++ +T Sbjct: 1039 IADVNDHTPVFDHTSYETSLPETTKVNTRFFALAATDIDLGDNGRISY--EIIEGNT--- 1093 Query: 73 EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132 + +F + G L RA LDRE+ Y + V D P SS Sbjct: 1094 --------------ERMFGVFP-DGYLFVRAPLDREERDYYALTVSCRDAGQPSR---SS 1135 Query: 133 TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192 + +++ID+NDN PQF+ T+T S+ E+ + + K+ A D D+G N+ + + + Sbjct: 1136 VVPVVIHVIDENDNAPQFTNSTFTFSIPENAPA--DTFVGKLTAVDRDIGRNAELSFTL- 1192 Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQV---------------------RSYRLV-IRAQ 230 TQ F+ID+ +G + ++ D E + +Y L+ Sbjct: 1193 SSQTQ-DFTIDTRNGFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVS 1251 Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290 D G P + ++ + + DVNDNAP F + + ++SE G I V DADEG+N Sbjct: 1252 DNGIPRLQDKVKVKVIVTDVNDNAPEFLRAPYHVTISEGASEGTHITHVFTQDADEGLNG 1311 Query: 291 ELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPPRSAT 349 ++ Y++ + G +L D +G + +LDRE+Q + L+V A D P S+ Sbjct: 1312 DVYYSLAKGNEAGQFNL----DSATGQLSLGRRLDRESQEIHHLIVVAKDAALKHPLSSN 1367 Query: 350 ATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGN 407 A+ F EV + E P GT ++ A+DAD+ ++++ + I+ GN Sbjct: 1368 ASITIVVLDENDNAPEFTQSSSEVSVLETSPTGTELMRFRASDADQGVNSQVVFSISAGN 1427 Query: 408 TRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNY 465 R F I S G + + +PLD++ Y L ++A+D G S T + + + D N+ Sbjct: 1428 RRDTFHIDSITGS--LYLHKPLDYEDITSYTLNITASDCGTPSLSTTVLYNVLVVDDNDN 1485 Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525 P+F + + E P+ T ++ V+A D D G+N +++Y++S + E + F Sbjct: 1486 PPIFPSTAIVRQIKEGIPLKTPIVTVTADDPDSGLNGKVSYAISKQ---EPQLPQGRHFG 1542 Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS---LSDTTDVEISVVDVNDNEPVF- 581 IN +TG I T + +DRE++ + LTV A D PS LS V + V D+NDN PVF Sbjct: 1543 INTETGVIHTLREIDRESIDTFRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAPVFV 1602 Query: 582 --KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639 + T+V QV A DAD NG + YE+ +E F + +G+I Sbjct: 1603 SMNAAILPPKFSTSKGSSTAVMQVHAKDADSSSNGLVTYEIVSGPQE--LFKLQRNTGII 1660 Query: 640 RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI-----EDINDSPPVFES-DCLT 693 + + L + D + + V+I I S P FE L+ Sbjct: 1661 TFTPGPQFKQEVRYQLTLKSTDEAVQSERRSSEVYITIITPGSGGSESSVPQFEQRSKLS 1720 Query: 694 FYISENSPIGTTIGEIRAH-DPDEGPNAVVHYSIKG--GDDSNSFSLETRQGSDKAELVT 750 + EN PIGT+I + AH E V + + G G F ++ + G L T Sbjct: 1721 GSVYENEPIGTSILTVTAHLASAEIEYFVTNVTATGSRGQVDRLFDIDAKLGI----LST 1776 Query: 751 MVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC 807 +LD E+ ++YE+ + A P + +V + V D ND+ P D ++N +D Sbjct: 1777 AAELDREAGPEEYEVEVYAIALGGQPRTSRTKVRVTVLDKNDSPPQFLDTPFVYNVSEDL 1836 Query: 808 FPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867 + A+D D + + ++ G++ LL +TG + L+ L+ + + Sbjct: 1837 QIGHTISTLRAHDPDTLGSVTFLLMDGHDGK-FLLEPSTGKLILNDTLDRETKSKYELRI 1895 Query: 868 SVTDGVNEIKAMMQLSV 884 V+DGV +A + V Sbjct: 1896 RVSDGVQYTEAYATIQV 1912 Score = 309 bits (759), Expect = 6e-82 Identities = 243/841 (28%), Positives = 388/841 (46%), Gaps = 61/841 (7%) Query: 90 FRIDGRSGALLTRASLDREKVARY--TVLVKATDQASPVSDRLS-STATIHVNIIDDNDN 146 FRID RSG + T LDRE+ A Y T+L ++ +S + +S +++ IID NDN Sbjct: 879 FRIDTRSGRITTARPLDREEQANYRLTILASSSSSSSAAASSVSYGQCIVNIAIIDLNDN 938 Query: 147 YPQFS---EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSID 203 P F+ E T+S+ E+ +V +++++ D D G NS I Y++ N QF I Sbjct: 939 APVFALDRESEPTISLPENAAVGQEIYLSRVR--DRDAGVNSRISYSLTN-NPNQQFRIG 995 Query: 204 SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263 ++G + L + + E + + A D GSP S+ L + I DVND+ P F + ++ Sbjct: 996 PVTGVLYLQRPIRAEPGSLIHVELMATDAGSPPLSSKLSLSVLIADVNDHTPVFDHTSYE 1055 Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323 S+ E + + A D D G N ++Y + + GN + + P G+++ Sbjct: 1056 TSLPETTKVNTRFFALAATDIDLGDNGRISYEIIE----GNTERMFGVFP-DGYLFVRAP 1110 Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383 LDRE + Y L V+ D G P RS+ F + + E+ P T Sbjct: 1111 LDREERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQFTNSTFTFSIPENAPADT 1170 Query: 384 PVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG----------RGLITVAQPLDFKQ 433 V LTA D D T + F+I ++NG L+ V++ + Sbjct: 1171 FVGKLTAVDRDIGRNAELSFTLSSQTQDFTIDTRNGFIKTLRPFDREALVKVSRNAEASG 1230 Query: 434 ER---------RYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFED 481 E Y+L + G D V++ +TD N+ AP F APY ++ E Sbjct: 1231 EDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPEFLRAPYHVTISEG 1290 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 A GT + V D+D G+N + YSL+ NEA QF ++ TG ++ + LDR Sbjct: 1291 ASEGTHITHVFTQDADEGLNGDVYYSLAK--GNEA-----GQFNLDSATGQLSLGRRLDR 1343 Query: 542 ETMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 E+ + L V A+D + LS + I V+D NDN P F Q +++E + GT + Sbjct: 1344 ESQEIHHLIVVAKDAALKHPLSSNASITIVVLDENDNAPEFTQSSSEVSVLETSPTGTEL 1403 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 + A+DAD G+N ++ + + +R + +F ID +G + +K LD E + ++ L A Sbjct: 1404 MRFRASDADQGVNSQVVFSISAGNRRD-TFHIDSITGSLYLHKPLDYEDITSYTLNITAS 1462 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 D GTP S+TV+ ++ + D ND+PP+F S + I E P+ T I + A DPD G N Sbjct: 1463 DCGTPSLSTTVLYNVLVVDDNDNPPIFPSTAIVRQIKEGIPLKTPIVTVTADDPDSGLNG 1522 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASP---PL 774 V Y+I + ++ + T+ ++D ES + L + A A P L Sbjct: 1523 KVSYAISKQEPQLPQGRHFGINTETGVIHTLREIDRES-IDTFRLTVVATDRAQPSERQL 1581 Query: 775 WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG---PFGRVPAYDADVTDK--LQY 829 + V ++V D+NDNAPV K G +V A DAD + + Y Sbjct: 1582 STEKLVTVIVEDINDNAPVFVSMNAAILPPKFSTSKGSSTAVMQVHAKDADSSSNGLVTY 1641 Query: 830 RILSGNNANLILLNETTGSMTLS--PQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887 I+SG L L TG +T + PQ V T++ S + V + ++ + +I Sbjct: 1642 EIVSGPQ-ELFKLQRNTGIITFTPGPQFKQEVRYQLTLK-STDEAVQSERRSSEVYITII 1699 Query: 888 T 888 T Sbjct: 1700 T 1700 Score = 309 bits (759), Expect = 6e-82 Identities = 255/895 (28%), Positives = 414/895 (46%), Gaps = 65/895 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D ND PVF + E ++ E + T V+ +KA D D G+N ++Y ++ + + Sbjct: 2155 ILIKDVNDEVPVF-ISANETAIMENVAINTVVIAVKAVDNDEGRNGYIDYLMKEARDEDM 2213 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 D F ++ G L +LDRE + Y + + A D+ P Sbjct: 2214 GQSDPL------------PFSLNPTDGQLRVVDALDRELRSSYLLNITARDRGEPPQ--- 2258 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+ + + + I+D+NDN P F K Y+ SV E+ S+ ++ ++ ATD D GAN IRY+ Sbjct: 2259 STESQLLIRILDENDNSPVFDPKQYSASVAENASI--GAMVLQVSATDVDEGANGRIRYS 2316 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLINIRD 249 I+ G+ FSI +G V + K L+YE++ Y L +RA+D + +T +L INI D Sbjct: 2317 IVLGDQNHDFSISEDTGVVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTINILD 2376 Query: 250 VNDNAPRFYTSLFQESVSENV--PIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYTGNVD 306 +NDN P F S + V EN P G ++ V AYDAD +N+++ Y + + G+ D Sbjct: 2377 INDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKE----GDSD 2432 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 L I+ SG + LDRE Q++Y L + A D G PP + T F Sbjct: 2433 L-FRINASSGDIALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVF 2491 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLIT 424 Y + E+ P GT V+T ATD DE + +L + + G + RF I S+ G I+ Sbjct: 2492 ELQSYHATVRENLPSGTHVLTPRATDKDEGLNAKLRFNLLGEHMH-RFHIDSETGE--IS 2548 Query: 425 VAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 A LD ++ Y LT+ A DS R+ + + I+++D N+ P F++ Y +V E Sbjct: 2549 TATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAVPER 2608 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 G V A D D G NA + Y++S F IN +TG ++T L Sbjct: 2609 ISKGEFVFGARALDLDDGENAVVHYTIS--------GRDQHYFDINTKTGVVSTKLELKT 2660 Query: 542 ETMS----GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM-EDALV 596 +T S Y + ++A D G SLS ++ + ++ + P F + M ED Sbjct: 2661 KTKSHDDLTYTIVISAMDQGEQSLSSKAELTV-ILRPPELFPTFAYMANSHFAMSEDVRP 2719 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK-ALDRESVATHDL 655 G +++V AT GL G+I Y + + S +DP SG++ + LD E +++ Sbjct: 2720 GKMITKVSATSPKKGLVGKIRYAIAGGIMGD-SLRVDPNSGLLSVGQDGLDYELTHLYEI 2778 Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 A DG TP S ++ + + D ND+ PV E + E I ++A D D Sbjct: 2779 WIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQLIYNAEVLEEESPPQLIAVVKASDRD 2838 Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---P 772 G N V Y ++ D +F + ++ E+ T + LD E Y V+ A P Sbjct: 2839 SGDNGNVIYRLQ-NDFDGTFEI-----TESGEIYTRMRLDREE-IGDYAFVVEAVDQGVP 2891 Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVTDKLQYRI 831 + V + + D NDN P K ++ N + +G F RV + D D+ Sbjct: 2892 HMTGTASVLLHLLDKNDNPP--KFTRLFSLNVTENAEIGSFVIRVTSSDLDLGANANASY 2949 Query: 832 -LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVR 885 S N + +G++T++ L+ ++V +DG + + ++++ Sbjct: 2950 SFSENPGEKFRIEPQSGNITVAGHLDREQQDEYILKVVASDGAWRAETPITITIQ 3004 Score = 307 bits (753), Expect = 3e-81 Identities = 258/827 (31%), Positives = 392/827 (47%), Gaps = 62/827 (7%) Query: 12 NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71 NVLD ND++P+F+ Y + V E T V+T+ A D D G N +EY+I D+ Sbjct: 2016 NVLDLNDNAPIFDPMSYSSEVFENVPIATEVVTVSAKDIDSGNNGLIEYSITAGDVDSEF 2075 Query: 72 PEDAXXXXXXXXXXVQD-----VFRIDGRSGA--LLTRASLDREKVA---RYTVLVKATD 121 D+ ++ + R A + + L+ ++ R + T Sbjct: 2076 GIDSNGTIRTRRNLDREHRSTYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQQTR 2135 Query: 122 Q---ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178 Q A RLSST + + I D ND P F T ++ E++++ N V+ +KA D Sbjct: 2136 QEFLAHQKQQRLSSTVKVTILIKDVNDEVPVFISANET-AIMENVAI--NTVVIAVKAVD 2192 Query: 179 ADVGANSAIRYAI-------IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD 231 D G N I Y + +G + + FS++ G + +V LD E SY L I A+D Sbjct: 2193 NDEGRNGYIDYLMKEARDEDMGQSDPLPFSLNPTDGQLRVVDALDRELRSSYLLNITARD 2252 Query: 232 GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE 291 G P +S +QLLI I D NDN+P F + SV+EN IG +++V A D DEG N Sbjct: 2253 RGEPPQSTESQLLIRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGR 2312 Query: 292 LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPPRSATA 350 + Y++ D N D I+ D +G V + L+ E ++Y L V A D + P TA Sbjct: 2313 IRYSIVLGDQ--NHDFSISED--TGVVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTA 2368 Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAED--EPPGTPVVTLTATDADE---DNRLHYEITG 405 F+ Y + E+ P G V+T+ A DAD ++++ Y + Sbjct: 2369 ELTINILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKE 2428 Query: 406 GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDAN 463 G++ F I + +G I + +PLD +Q+ Y LT+ A D+G + T +V++ + D N Sbjct: 2429 GDS-DLFRINASSGD--IALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDIN 2485 Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523 + PVFE Y A+V E+ P GT VL ATD D G+NA++ ++L E H + Sbjct: 2486 DNDPVFELQSYHATVRENLPSGTHVLTPRATDKDEGLNAKLRFNLLGE--------HMHR 2537 Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFK 582 F I+ +TG I+T LDRE S Y LT+ A+D + + + ++ ISV DVNDN P F Sbjct: 2538 FHIDSETGEISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFD 2597 Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642 Y + E G V A D D G N +HY + +D+ F I+ +GV+ T Sbjct: 2598 STTYNVAVPERISKGEFVFGARALDLDDGENAVVHYTISGRDQH--YFDINTKTGVVSTK 2655 Query: 643 KALDRESVATHDLKAV----AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698 L ++ + DL A+D G SS + + + P F +SE Sbjct: 2656 LELKTKTKSHDDLTYTIVISAMDQGEQSLSSKAELTVILRPPELFPTFAYMANSHFAMSE 2715 Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758 + G I ++ A P +G + Y+I GG +S ++ G V LDYE Sbjct: 2716 DVRPGKMITKVSATSPKKGLVGKIRYAIAGGIMGDSLRVDPNSG---LLSVGQDGLDYEL 2772 Query: 759 PRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN 802 YE+ I AA +P L + + + VTD NDNAPVM+ Q+I+N Sbjct: 2773 TH-LYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVME--QLIYN 2816 Score = 299 bits (733), Expect = 9e-79 Identities = 268/906 (29%), Positives = 416/906 (45%), Gaps = 80/906 (8%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 ++ I+V D ND+ P F+ Y +V E S G V +A D D G+NA V YTI Sbjct: 2580 VNLTISVSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALDLDDGENAVVHYTI---- 2635 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR----YTVLVKATDQ 122 + D Q F I+ ++G + T+ L + + YT+++ A DQ Sbjct: 2636 ----SGRD------------QHYFDINTKTGVVSTKLELKTKTKSHDDLTYTIVISAMDQ 2679 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT-VSVDEDISVTDNPVIAKIKATDADV 181 LSS A + V I+ + +P F+ + ++ ED V +I K+ AT Sbjct: 2680 G---EQSLSSKAELTV-ILRPPELFPTFAYMANSHFAMSED--VRPGKMITKVSATSPKK 2733 Query: 182 GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNT 240 G IRYAI GG +D SG +S+ + LDYE Y + I A DG +PS + Sbjct: 2734 GLVGKIRYAIAGGIMGDSLRVDPNSGLLSVGQDGLDYELTHLYEIWIEAADGDTPSLRSV 2793 Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 T + +N+ D NDNAP ++ V E I V+A D D G N + Y + D Sbjct: 2794 TLITLNVTDANDNAPVMEQLIYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRL-QND 2852 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 + G ++ SG +YT +LDRE Y +V A D G P + TA+ Sbjct: 2853 FDGTFEI-----TESGEIYTRMRLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKN 2907 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG-RFSITSQNG 419 F + + + E+ G+ V+ +T++D D + + G +F I Q+G Sbjct: 2908 DNPPKF-TRLFSLNVTENAEIGSFVIRVTSSDLDLGANANASYSFSENPGEKFRIEPQSG 2966 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479 ITVA LD +Q+ Y+L V A+D R++T + I I D N+ AP FE++ Y+ S Sbjct: 2967 N--ITVAGHLDREQQDEYILKVVASDGAWRAETP-ITITIQDQNDNAPEFEHSFYSFSFP 3023 Query: 480 EDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 E V + ATD D G N+ I+YSL F I+P TG + + K Sbjct: 3024 ELQQSIALVGQIIATDRDKQGPNSVISYSLQQP---------SPMFSIDPATGEVFSKKA 3074 Query: 539 LD-------RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 + R + Y LTV A D G P L V I++VD ++N P F+Q Y A + Sbjct: 3075 VRFKHSQYVRSPENMYALTVLATDNGKPPLYSECLVNINIVDAHNNPPKFEQAEYLAPLP 3134 Query: 592 EDALVGTSVSQVGATD-ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650 +DA+ G + +V A D D+G N + Y L + F + G I K + Sbjct: 3135 QDAVRGQRIVRVHANDKQDLGTN-EMDYSLMTFNL-SSIFSVGRHDGWITLVKPIQVPPN 3192 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710 ++L A D G PPQS V I + N P F + + EN P+G+TI + Sbjct: 3193 TRYELVVRATDRGVPPQSDETRVVIVVTGENMDTPRFSVNSYQVIVPENEPVGSTILTVG 3252 Query: 711 AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770 A D D GPN ++ YSI GG++ FS++ R G +V LDY+ ++Y L I Sbjct: 3253 ATDDDTGPNGMLRYSISGGNERQDFSVDERTGG----IVIQQQLDYDL-IQEYHLNITVQ 3307 Query: 771 S---PPLWNDVRVEILVTDVNDNAPVM--KDFQIIFNNYKDCFPVGPF-GRVPAYDADVT 824 PL + + I++TDVNDN PV K++ K PVG F + A D D Sbjct: 3308 DLGYHPLSSVAMLTIILTDVNDNPPVFNHKEYHCYIPENK---PVGTFVFQAHAADKDSP 3364 Query: 825 DK--LQYRIL-SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQ 881 + Y L SG + + ++N++ G+++ + + ++ T+++ + + +++ Sbjct: 3365 KNAIIHYAFLPSGPDRHFFIMNQSNGTISSAVSFDYEERRIYTLQIKAKNPDSSMESYAN 3424 Query: 882 LSVRLI 887 L V ++ Sbjct: 3425 LYVHVL 3430 Score = 298 bits (732), Expect = 1e-78 Identities = 265/906 (29%), Positives = 428/906 (47%), Gaps = 88/906 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ V D ND+ PVFE+Q Y A+VRE SGT VLT +ATD+D G NA++ + + + Sbjct: 2478 RVEVQDINDNDPVFELQSYHATVRENLPSGTHVLTPRATDKDEGLNAKLRFNL---LGEH 2534 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 ++ F ID +G + T +LDRE+ + Y + + A D S +++ Sbjct: 2535 MHR-----------------FHIDSETGEISTATTLDREETSVYHLTLMAQD--SSITEP 2575 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 +S+ + +++ D NDN P+F TY V+V E IS + +A D D G N+ + Y Sbjct: 2576 RASSVNLTISVSDVNDNIPKFDSTTYNVAVPERIS--KGEFVFGARALDLDDGENAVVHY 2633 Query: 190 AIIGGNTQMQFSIDSLSGDVSL-----VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 I G Q F I++ +G VS KT ++ + +Y +VI A D G S S+ +L Sbjct: 2634 T-ISGRDQHYFDINTKTGVVSTKLELKTKTKSHDDL-TYTIVISAMDQGEQSLSSKAELT 2691 Query: 245 INIRDVNDNAPRF-YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 + +R + P F Y + ++SE+V G I +V A +G+ ++ Y + G Sbjct: 2692 VILRP-PELFPTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRYAIAG----G 2746 Query: 304 NVDLPITIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 + + +DP SG + + GQ LD E Y++ + A DG P + Sbjct: 2747 IMGDSLRVDPNSG-LLSVGQDGLDYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDAND 2805 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419 Y E+ E+E P + + A+D D ++ + Y + + G F IT Sbjct: 2806 NAPVMEQLIYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRLQ-NDFDGTFEITES-- 2862 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477 G I LD ++ Y V A D G + TA V +++ D N+ P F ++ + Sbjct: 2863 -GEIYTRMRLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPKFTRL-FSLN 2920 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 V E+A IG+ V+ V+++D D+G NA +YS S + ++F I PQ+G IT Sbjct: 2921 VTENAEIGSFVIRVTSSDLDLGANANASYSFSE--------NPGEKFRIEPQSGNITVAG 2972 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LDRE Y+L V A DG + T + I++ D NDN P F+ Y+ + E Sbjct: 2973 HLDREQQDEYILKVVASDG---AWRAETPITITIQDQNDNAPEFEHSFYSFSFPELQQSI 3029 Query: 598 TSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD-------RES 649 V Q+ ATD D G N I Y L + F IDPA+G + + KA+ R Sbjct: 3030 ALVGQIIATDRDKQGPNSVISYSL---QQPSPMFSIDPATGEVFSKKAVRFKHSQYVRSP 3086 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 + L +A D G PP S +V+I I D +++PP FE + +++ G I + Sbjct: 3087 ENMYALTVLATDNGKPPLYSECLVNINIVDAHNNPPKFEQAEYLAPLPQDAVRGQRIVRV 3146 Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 A+D + + YS+ + S+ FS+ G +T+V P +YELV+RA Sbjct: 3147 HANDKQDLGTNEMDYSLMTFNLSSIFSVGRHDG-----WITLVKPIQVPPNTRYELVVRA 3201 Query: 770 AS---PPLWNDVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFPVG-PFGRVPAYDADV 823 PP ++ RV I+VT N + P + +Q+I + PVG V A D D Sbjct: 3202 TDRGVPPQSDETRVVIVVTGENMDTPRFSVNSYQVIVPENE---PVGSTILTVGATDDDT 3258 Query: 824 --TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMM 880 L+Y I GN ++E TG + + QL+ ++ + + ++V D G + + ++ Sbjct: 3259 GPNGMLRYSISGGNERQDFSVDERTGGIVIQQQLDYDLIQEYHLNITVQDLGYHPLSSVA 3318 Query: 881 QLSVRL 886 L++ L Sbjct: 3319 MLTIIL 3324 Score = 292 bits (716), Expect = 1e-76 Identities = 257/874 (29%), Positives = 414/874 (47%), Gaps = 56/874 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD-T 69 I+V+D ND++P F + S+ E A + T V L A D+DIG+NAE+ +T+ T D T Sbjct: 1141 IHVIDENDNAPQFTNSTFTFSIPENAPADTFVGKLTAVDRDIGRNAELSFTLSSQTQDFT 1200 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 ++ + + + ++ + A SL R +A +L++AT + + R Sbjct: 1201 IDTRNGFIKTLRPFDR-EALVKVSRNAEASGEDGSL-RGSMAGNYMLLEATVSDNGI-PR 1257 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L + V + D NDN P+F Y V++ E S + I + DAD G N + Y Sbjct: 1258 LQDKVKVKVIVTDVNDNAPEFLRAPYHVTISEGAS--EGTHITHVFTQDADEGLNGDVYY 1315 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG--SPSRSNTTQLLINI 247 ++ GN QF++DS +G +SL + LD E + L++ A+D P SN + + I + Sbjct: 1316 SLAKGNEAGQFNLDSATGQLSLGRRLDRESQEIHHLIVVAKDAALKHPLSSNAS-ITIVV 1374 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 D NDNAP F S + SV E P G ++R +A DAD+GVN+++ ++++ GN Sbjct: 1375 LDENDNAPEFTQSSSEVSVLETSPTGTELMRFRASDADQGVNSQVVFSIS----AGNRRD 1430 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 ID +G +Y LD E Y L +TA+D G P S T F Sbjct: 1431 TFHIDSITGSLYLHKPLDYEDITSYTLNITASDCGTPSLSTTVLYNVLVVDDNDNPPIFP 1490 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGN---TRGR-FSITSQNGRG 421 ++ E P TP+VT+TA D D + ++ Y I+ +GR F I ++ G Sbjct: 1491 STAIVRQIKEGIPLKTPIVTVTADDPDSGLNGKVSYAISKQEPQLPQGRHFGINTET--G 1548 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGRSD-----TAMVQINITDANNYAPVF--ENAPY 474 +I + +D + + LTV ATD S+ +V + + D N+ APVF NA Sbjct: 1549 VIHTLREIDRESIDTFRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAPVFVSMNAAI 1608 Query: 475 TASVFEDAP-IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 F + T V+ V A D+D N +TY E V+ + F + TG I Sbjct: 1609 LPPKFSTSKGSSTAVMQVHAKDADSSSNGLVTY--------EIVSGPQELFKLQRNTGII 1660 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV-----DVNDNEPVFKQQ-LYT 587 T + Y LT+ + D V S +++V I+++ + P F+Q+ + Sbjct: 1661 TFTPGPQFKQEVRYQLTLKSTDEAVQSERRSSEVYITIITPGSGGSESSVPQFEQRSKLS 1720 Query: 588 ANIMEDALVGTSVSQVGA--TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645 ++ E+ +GTS+ V A A++ + + + F ID G++ T L Sbjct: 1721 GSVYENEPIGTSILTVTAHLASAEIEYFVTNVTATGSRGQVDRLFDIDAKLGILSTAAEL 1780 Query: 646 DRES-VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 DRE+ ++++ AI G P++S V + + D NDSPP F + +SE+ IG Sbjct: 1781 DREAGPEEYEVEVYAIALGGQPRTSRTKVRVTVLDKNDSPPQFLDTPFVYNVSEDLQIGH 1840 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764 TI +RAHDPD V + + G D F LE G +L+ LD E+ + KYE Sbjct: 1841 TISTLRAHDPD--TLGSVTFLLMDGHD-GKFLLEPSTG----KLILNDTLDRET-KSKYE 1892 Query: 765 LVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV- 823 L IR + + + I V+D NDN P+ +D F+ ++ G++ A DAD+ Sbjct: 1893 LRIRVSDGVQYTEAYATIQVSDTNDNPPLFEDTVYSFDIPENAQRGYQVGQIVARDADLG 1952 Query: 824 -TDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 +L Y ++S ++ LN TG +TL+ +L+ Sbjct: 1953 QNAQLSYGVVSDWANDVFSLNPQTGMLTLTARLD 1986 Score = 287 bits (703), Expect = 4e-75 Identities = 244/842 (28%), Positives = 396/842 (47%), Gaps = 106/842 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I VLD ND++P F E SV E + +GT ++ +A+D D G N++V ++I Sbjct: 1372 IVVLDENDNAPEFTQSSSEVSVLETSPTGTELMRFRASDADQGVNSQVVFSISAGNR--- 1428 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +D F ID +G+L LD E + YT+ + A+D +P L Sbjct: 1429 ----------------RDTFHIDSITGSLYLHKPLDYEDITSYTLNITASDCGTP---SL 1469 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+T +V ++DDNDN P F + E I + P++ + A D D G N + YA Sbjct: 1470 STTVLYNVLVVDDNDNPPIFPSTAIVRQIKEGIPLK-TPIVT-VTADDPDSGLNGKVSYA 1527 Query: 191 IIGGNTQM----QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLI 245 I Q+ F I++ +G + ++ +D E + ++RL + A D PS R +T+ L+ Sbjct: 1528 ISKQEPQLPQGRHFGINTETGVIHTLREIDRESIDTFRLTVVATDRAQPSERQLSTEKLV 1587 Query: 246 NI--RDVNDNAPRFYT---SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 + D+NDNAP F + ++ S + ++++V A DAD N +TY + Sbjct: 1588 TVIVEDINDNAPVFVSMNAAILPPKFSTSKGSSTAVMQVHAKDADSSSNGLVTYEIV--- 1644 Query: 301 YTGNVDLPITIDPRSGWV-YTSGQLDRETQAKYQLLVTATDGG-DPPRSATATXXXXXXX 358 +G +L + +G + +T G ++ + +YQL + +TD R ++ Sbjct: 1645 -SGPQEL-FKLQRNTGIITFTPGPQFKQ-EVRYQLTLKSTDEAVQSERRSSEVYITIITP 1701 Query: 359 XXXXXXXFMPGQYEVE------LAEDEPPGTPVVTLTATDADEDNRLHY-EITGGNTRGR 411 +P Q+E + E+EP GT ++T+TA A + +T +RG+ Sbjct: 1702 GSGGSESSVP-QFEQRSKLSGSVYENEPIGTSILTVTAHLASAEIEYFVTNVTATGSRGQ 1760 Query: 412 ----FSITSQNGRGLITVAQPLDFKQ-ERRYVLTVSATDSGGRSDTAMVQINIT--DANN 464 F I ++ G+++ A LD + Y + V A GG+ T+ ++ +T D N+ Sbjct: 1761 VDRLFDIDAK--LGILSTAAELDREAGPEEYEVEVYAIALGGQPRTSRTKVRVTVLDKND 1818 Query: 465 YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524 P F + P+ +V ED IG T+ + A D D +T+ L HD +F Sbjct: 1819 SPPQFLDTPFVYNVSEDLQIGHTISTLRAHDPDT--LGSVTFLLMDG--------HDGKF 1868 Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584 ++ P TG + N LDRET S Y L + DG + + T I V D NDN P+F+ Sbjct: 1869 LLEPSTGKLILNDTLDRETKSKYELRIRVSDGVQYTEAYAT---IQVSDTNDNPPLFEDT 1925 Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA 644 +Y+ +I E+A G V Q+ A DAD+G N ++ Y + D F ++P +G++ Sbjct: 1926 VYSFDIPENAQRGYQVGQIVARDADLGQNAQLSYGV-VSDWANDVFSLNPQTGMLTLTAR 1984 Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 LD E V + L A D G P S+T+ V+ + D+ND+ P+F+ + + EN PI T Sbjct: 1985 LDYEEVQHYILIVQAQDNGQPSLSTTITVYCNVLDLNDNAPIFDPMSYSSEVFENVPIAT 2044 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE------TRQGSDK------------- 745 + + A D D G N ++ YSI GD + F ++ TR+ D+ Sbjct: 2045 EVVTVSAKDIDSGNNGLIEYSITAGDVDSEFGIDSNGTIRTRRNLDREHRSTYTLTVTAR 2104 Query: 746 ---------AEL-VTMVDLDYESPRK----KYELVIRAASPPLWNDVRVEILVTDVNDNA 791 +EL T + L Y SPRK + E + L + V+V IL+ DVND Sbjct: 2105 DCADEFASFSELEETQLKLKYRSPRKYQQTRQEFLAHQKQQRLSSTVKVTILIKDVNDEV 2164 Query: 792 PV 793 PV Sbjct: 2165 PV 2166 Score = 285 bits (699), Expect = 1e-74 Identities = 273/932 (29%), Positives = 411/932 (44%), Gaps = 88/932 (9%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 I +I VLD ND+SP F S E A+SGT +L ATD D+G+N V E+V Sbjct: 140 IEVRIKVLDVNDNSPEFPEPSIAISFSESATSGTRLLLDAATDADVGENG-VTDQYEIVA 198 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 + D D + L T +LDRE Y + + A D SP Sbjct: 199 GNV----DNKFRLVTTANPSGDTSYLH-----LETTGNLDRESRGSYQLNISARDGGSPP 249 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 ++V I+D NDN P F Y VS++E ++ PV+ + A+D D+G NS Sbjct: 250 R---FGYLQVNVTILDVNDNPPIFDHSDYNVSLNE-TALPGTPVVT-VMASDNDLGDNSK 304 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQ---------VRSYRLVIRAQDGGSPSR 237 I Y + T+ QF+++ +G +S + ++ Q +S + A+D GSP + Sbjct: 305 ITYYL--AETEHQFTVNPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFARDHGSPRQ 362 Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQE-----SVSENVPIGYSIVRVQAYDADEGVNAEL 292 T + +N+ D ND+ P F + +V EN G + V D+D G+N Sbjct: 363 DGRTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDENAVNGTVVAAVAVKDSDSGLNGRT 422 Query: 293 TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352 + + + G+ L D V +G LDRE KY L V A D G P R+ TA Sbjct: 423 SVRIVSGNELGHFRLEEAADLHI--VRVNGVLDREEIGKYNLTVVAMDQGTPARTTTAHL 480 Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRG 410 F +Y L+E P G+ V ++TATD D + ++HY+I GN Sbjct: 481 IIDVNDVNDHEPVFEKSEYSAVLSELAPTGSFVASITATDEDTGVNAQVHYDILSGNELK 540 Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYAPV 468 FS+ GLI PLD + L++SA D G A Q+ I D N+ AP Sbjct: 541 WFSMDPLT--GLIVTTGPLDREIRDTVELSISARDGGPNPKFAYTQLKVIILDENDEAPQ 598 Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528 F ++ EDAP T V +++ATD D G N +T++L+ + + QF ++ Sbjct: 599 FSQREQNVTLGEDAPPQTIVALMTATDHDQGTNGSVTFALAPSVER----LYPLQFALDA 654 Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVF--KQQL 585 TG +TT + LDRE MS Y ++V ARD G P+ S T V ++V DVNDN+P F + + Sbjct: 655 LTGQLTTRRPLDREKMSQYEISVIARDQGAPTPQSATATVWLNVADVNDNDPQFYPRHYI 714 Query: 586 YT-ANIMEDALVGTSVSQ------VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638 Y+ A+ +D + V + V A+D D G N I Y L+ EG F +D SG Sbjct: 715 YSLADDDDDIKLKKEVEKERILLHVTASDKDDGDNALIEYRLE--SGGEGLFQLDARSGA 772 Query: 639 I--RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC--LTF 694 I R + + L A D G IV I ++ + ++ F Sbjct: 773 ISLRGDAPASMHWKPHYKLLVSARDAGQRRSQQDAIVEIVLKSKLEMLECGQAQAGGYEF 832 Query: 695 YISE------NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAEL 748 + E NS +G ++ + N+ + Y I GD + +F ++TR G + Sbjct: 833 QMVEDHEQQRNSQPNREVGIVQVKSTNGKANSHIEYDIIQGDRAQNFRIDTRSG----RI 888 Query: 749 VTMVDLDYESPRKKYELVI---------RAASPPLWNDVRVEILVTDVNDNAPVM---KD 796 T LD E + Y L I AAS + V I + D+NDNAPV ++ Sbjct: 889 TTARPLDREE-QANYRLTILASSSSSSSAAASSVSYGQCIVNIAIIDLNDNAPVFALDRE 947 Query: 797 FQIIFNNYKDCFPVGP---FGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSP 853 + + ++ VG RV DA V ++ Y L+ N + TG + L Sbjct: 948 SEPTISLPENA-AVGQEIYLSRVRDRDAGVNSRISYS-LTNNPNQQFRIGPVTGVLYLQR 1005 Query: 854 QLNTNVPKLATMEVSVTD-GVNEIKAMMQLSV 884 + L +E+ TD G + + + LSV Sbjct: 1006 PIRAEPGSLIHVELMATDAGSPPLSSKLSLSV 1037 Score = 283 bits (695), Expect = 4e-74 Identities = 214/694 (30%), Positives = 332/694 (47%), Gaps = 64/694 (9%) Query: 90 FRIDGRSGALLTRASLDREKVA-RYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 F +D +G + T LDRE + Y ++V ++ P+ + + ++D NDN P Sbjct: 103 FTLDPVTGEVKTNVVLDREGMRDHYDLVVLSSQPTYPIE--------VRIKVLDVNDNSP 154 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI-RYAIIGGNTQMQFSIDSL-- 205 +F E + +S E S T + ATDADVG N +Y I+ GN +F + + Sbjct: 155 EFPEPSIAISFSE--SATSGTRLLLDAATDADVGENGVTDQYEIVAGNVDNKFRLVTTAN 212 Query: 206 -SGDVSLVK-----TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259 SGD S + LD E SY+L I A+DGGSP R Q+ + I DVNDN P F Sbjct: 213 PSGDTSYLHLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDH 272 Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319 S + S++E G +V V A D D G N+++TY Y + T++P +G + Sbjct: 273 SDYNVSLNETALPGTPVVTVMASDNDLGDNSKITY------YLAETEHQFTVNPETGVIS 326 Query: 320 TSGQLD--RETQAKYQ-------LLVTATDGGDPPRS----ATATXXXXXXXXXXXXXXF 366 T+ +++ ++T K V A D G P + T F Sbjct: 327 TTERVNCPQQTNVKSSASQKSCVFTVFARDHGSPRQDGRTYVTVNLLDTNDHDPIISFRF 386 Query: 367 MP-GQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLI 423 P G + E+ GT V + D+D + R I GN G F + ++ Sbjct: 387 FPDGGKVATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRIVSGNELGHFRLEEAADLHIV 446 Query: 424 TVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 V LD ++ +Y LTV A D G R+ TA + I++ D N++ PVFE + Y+A + E Sbjct: 447 RVNGVLDREEIGKYNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEPVFEKSEYSAVLSEL 506 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 AP G+ V ++ATD D G+NAQ+ Y + S NE + F ++P TG I T LDR Sbjct: 507 APTGSFVASITATDEDTGVNAQVHYDILS--GNEL-----KWFSMDPLTGLIVTTGPLDR 559 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 E L+++ARDGG T +++ ++D ND P F Q+ + EDA T V+ Sbjct: 560 EIRDTVELSISARDGGPNPKFAYTQLKVIILDENDEAPQFSQREQNVTLGEDAPPQTIVA 619 Query: 602 QVGATDADVGLNGRIHYELDPKDRE--EGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 + ATD D G NG + + L P F +D +G + T + LDRE ++ +++ +A Sbjct: 620 LMTATDHDQGTNGSVTFALAPSVERLYPLQFALDALTGQLTTRRPLDREKMSQYEISVIA 679 Query: 660 IDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR-------- 710 D G P PQS+T V + + D+ND+ P F + ++++ E+ Sbjct: 680 RDQGAPTPQSATATVWLNVADVNDNDPQFYPRHYIYSLADDDDDIKLKKEVEKERILLHV 739 Query: 711 -AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 A D D+G NA++ Y ++ G + F L+ R G+ Sbjct: 740 TASDKDDGDNALIEYRLESGGE-GLFQLDARSGA 772 Score = 268 bits (657), Expect = 1e-69 Identities = 251/879 (28%), Positives = 401/879 (45%), Gaps = 90/879 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI-ELVTADT 69 + +LD ND+ P+F+ Y S+ E A GT V+T+ A+D D+G N+++ Y + E T Sbjct: 258 VTILDVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDNDLGDNSKITYYLAETEHQFT 317 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 +NPE Q + +S A +K +TV A D SP D Sbjct: 318 VNPETGVISTTERVNCPQQT---NVKSSA--------SQKSCVFTVF--ARDHGSPRQD- 363 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTY-----TVSVDEDISVTDNPVIAKIKATDADVGAN 184 + VN++D ND+ P S + + +VDE+ + V+A + D+D G N Sbjct: 364 --GRTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDEN--AVNGTVVAAVAVKDSDSGLN 419 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRSNTT 241 I+ GN F ++ + D+ +V+ LD E++ Y L + A D G+P+R+ T Sbjct: 420 GRTSVRIVSGNELGHFRLEE-AADLHIVRVNGVLDREEIGKYNLTVVAMDQGTPARTTTA 478 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 L+I++ DVND+ P F S + +SE P G + + A D D GVNA++ Y + Sbjct: 479 HLIIDVNDVNDHEPVFEKSEYSAVLSELAPTGSFVASITATDEDTGVNAQVHYDIL---- 534 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 +GN ++DP +G + T+G LDRE + +L ++A DGG P+ A Sbjct: 535 SGNELKWFSMDPLTGLIVTTGPLDREIRDTVELSISARDGGPNPKFAYTQLKVIILDEND 594 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRG---RFSITS 416 F + V L ED PP T V +TATD D+ + + + + R +F++ + Sbjct: 595 EAPQFSQREQNVTLGEDAPPQTIVALMTATDHDQGTNGSVTFALAPSVERLYPLQFALDA 654 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAP 473 G+ +T +PLD ++ +Y ++V A D G +S TA V +N+ D N+ P F Sbjct: 655 LTGQ--LTTRRPLDREKMSQYEISVIARDQGAPTPQSATATVWLNVADVNDNDPQFYPRH 712 Query: 474 YTASVFED---------APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524 Y S+ +D +L V+A+D D G NA I Y L S E + F Sbjct: 713 YIYSLADDDDDIKLKKEVEKERILLHVTASDKDDGDNALIEYRLES--GGEGL------F 764 Query: 525 VINPQTGAITT--NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582 ++ ++GAI+ + Y L V+ARD G VEI + + + Sbjct: 765 QLDARSGAISLRGDAPASMHWKPHYKLLVSARDAGQRRSQQDAIVEIVLKSKLEMLECGQ 824 Query: 583 QQL--YTANIMED------ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634 Q Y ++ED + V V + N I Y++ DR + +F ID Sbjct: 825 AQAGGYEFQMVEDHEQQRNSQPNREVGIVQVKSTNGKANSHIEYDIIQGDRAQ-NFRIDT 883 Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST------VIVHIKIEDINDSPPVFE 688 SG I T + LDRE A + L +A + +++ IV+I I D+ND+ PVF Sbjct: 884 RSGRITTARPLDREEQANYRLTILASSSSSSSAAASSVSYGQCIVNIAIIDLNDNAPVFA 943 Query: 689 SDCL---TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745 D T + EN+ +G I R D D G N+ + YS+ +N+ + + R G Sbjct: 944 LDRESEPTISLPENAAVGQEIYLSRVRDRDAGVNSRISYSL-----TNNPNQQFRIGPVT 998 Query: 746 AELVTMVDLDYESPRKKY-ELVIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN 803 L + E + EL+ A SPPL + + + +L+ DVND+ PV D + Sbjct: 999 GVLYLQRPIRAEPGSLIHVELMATDAGSPPLSSKLSLSVLIADVNDHTPVF-DHTSYETS 1057 Query: 804 YKDCFPVGP-FGRVPAYDADVTD--KLQYRILSGNNANL 839 + V F + A D D+ D ++ Y I+ GN + Sbjct: 1058 LPETTKVNTRFFALAATDIDLGDNGRISYEIIEGNTERM 1096 Score = 214 bits (522), Expect = 3e-53 Identities = 163/514 (31%), Positives = 253/514 (49%), Gaps = 51/514 (9%) Query: 310 TIDPRSGWVYTSGQLDRE-TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 T+DP +G V T+ LDRE + Y L+V ++ P F Sbjct: 104 TLDPVTGEVKTNVVLDREGMRDHYDLVVLSSQPTYP-----IEVRIKVLDVNDNSPEFPE 158 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADE-DNRL--HYEITGGNTRGRFS-ITSQNGRG--- 421 + +E GT ++ ATDAD +N + YEI GN +F +T+ N G Sbjct: 159 PSIAISFSESATSGTRLLLDAATDADVGENGVTDQYEIVAGNVDNKFRLVTTANPSGDTS 218 Query: 422 --LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTAS 477 + LD + Y L +SA D G +Q+N+T D N+ P+F+++ Y S Sbjct: 219 YLHLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVS 278 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 + E A GT V+ V A+D+D+G N++ITY L A + QF +NP+TG I+T + Sbjct: 279 LNETALPGTPVVTVMASDNDLGDNSKITYYL---------AETEHQFTVNPETGVISTTE 329 Query: 538 LLD---------RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY-- 586 ++ + + TV ARD G P T V ++++D ND++P+ + + Sbjct: 330 RVNCPQQTNVKSSASQKSCVFTVFARDHGSPRQDGRTYVTVNLLDTNDHDPIISFRFFPD 389 Query: 587 ---TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG--VIRT 641 A + E+A+ GT V+ V D+D GLNGR + E G F ++ A+ ++R Sbjct: 390 GGKVATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRI-VSGNELGHFRLEEAADLHIVRV 448 Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701 N LDRE + ++L VA+D GTP +++T + I + D+ND PVFE + +SE +P Sbjct: 449 NGVLDREEIGKYNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEPVFEKSEYSAVLSELAP 508 Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761 G+ + I A D D G NA VHY I G++ FS++ G +VT LD E R Sbjct: 509 TGSFVASITATDEDTGVNAQVHYDILSGNELKWFSMDPLTGL----IVTTGPLDREI-RD 563 Query: 762 KYELVI--RAASP-PLWNDVRVEILVTDVNDNAP 792 EL I R P P + ++++++ D ND AP Sbjct: 564 TVELSISARDGGPNPKFAYTQLKVIILDENDEAP 597 Score = 196 bits (477), Expect = 1e-47 Identities = 142/415 (34%), Positives = 205/415 (49%), Gaps = 16/415 (3%) Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509 S T V I I D N+ PVF +A TA + E+ I T V+ V A D+D G N I Y L Sbjct: 2148 SSTVKVTILIKDVNDEVPVFISANETA-IMENVAINTVVIAVKAVDNDEGRNGYIDY-LM 2205 Query: 510 SEISNEAVAHHDQ-QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568 E +E + D F +NP G + LDRE S YLL +TARD G P S + + Sbjct: 2206 KEARDEDMGQSDPLPFSLNPTDGQLRVVDALDRELRSSYLLNITARDRGEPPQSTESQLL 2265 Query: 569 ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG 628 I ++D NDN PVF + Y+A++ E+A +G V QV ATD D G NGRI Y + D+ Sbjct: 2266 IRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGRIRYSIVLGDQNH- 2324 Query: 629 SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVF 687 F I +GV+R K L+ E ++ + L A D P T + I I DIND+ P F Sbjct: 2325 DFSISEDTGVVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTINILDINDNRPTF 2384 Query: 688 ESDCLTFYISENS--PIGTTIGEIRAHDPDEGP-NAVVHYSIKGGDDSNSFSLETRQGSD 744 + EN+ P G + + A+D D P N+ V Y +K G DS+ F + G Sbjct: 2385 LDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKEG-DSDLFRINASSGD- 2442 Query: 745 KAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY 804 L+ +D + +S + + SPPL V + V D+NDN PV + Q Sbjct: 2443 -IALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVF-ELQSYHATV 2500 Query: 805 KDCFPVGPFGRVP-AYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 ++ P G P A D D + KL++ +L G + + ++ TG ++ + L+ Sbjct: 2501 RENLPSGTHVLTPRATDKDEGLNAKLRFNLL-GEHMHRFHIDSETGEISTATTLD 2554 Score = 151 bits (366), Expect = 3e-34 Identities = 131/460 (28%), Positives = 204/460 (44%), Gaps = 34/460 (7%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT-YSL-SSEI 512 V+I + D N+ +P F S E A GT +L+ +ATD+DVG N Y + + + Sbjct: 142 VRIKVLDVNDNSPEFPEPSIAISFSESATSGTRLLLDAATDADVGENGVTDQYEIVAGNV 201 Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572 N+ + + T LDRE+ Y L ++ARDGG P V ++++ Sbjct: 202 DNKFRLVTTANPSGDTSYLHLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTIL 261 Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632 DVNDN P+F Y ++ E AL GT V V A+D D+G N +I Y L + + F + Sbjct: 262 DVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDNDLGDNSKITYYLAETEHQ---FTV 318 Query: 633 DPASGVIRTNKALD-------RESVATHD--LKAVAIDGGTPPQSSTVIVHIKIEDINDS 683 +P +GVI T + ++ + S + A D G+P Q V + + D ND Sbjct: 319 NPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFARDHGSPRQDGRTYVTVNLLDTNDH 378 Query: 684 PPV-----FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738 P+ F + EN+ GT + + D D G N I G++ F LE Sbjct: 379 DPIISFRFFPDGGKVATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRIVSGNELGHFRLE 438 Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMK 795 + +D + LD E K Y L + A +P + I V DVND+ PV + Sbjct: 439 --EAADLHIVRVNGVLDREEIGK-YNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEPVFE 495 Query: 796 --DFQIIFNNYKDCFPVGPF-GRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMT 850 ++ + + + P G F + A D D V ++ Y ILSGN ++ TG + Sbjct: 496 KSEYSAVLS---ELAPTGSFVASITATDEDTGVNAQVHYDILSGNELKWFSMDPLTGLIV 552 Query: 851 LSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITE 889 + L+ + + +S D G N A QL V ++ E Sbjct: 553 TTGPLDREIRDTVELSISARDGGPNPKFAYTQLKVIILDE 592 Score = 97.1 bits (231), Expect = 6e-18 Identities = 83/280 (29%), Positives = 123/280 (43%), Gaps = 24/280 (8%) Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 G T + + Y + RE F +DP +G ++TN LDRE + H V Sbjct: 80 GTTVGFIPTKPKFSYRFNEPPRE---FTLDPVTGEVKTNVVLDREGMRDHYDLVVLSSQP 136 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV- 722 T P + V IK+ D+ND+ P F + SE++ GT + A D D G N V Sbjct: 137 TYP----IEVRIKVLDVNDNSPEFPEPSIAISFSESATSGTRLLLDAATDADVGENGVTD 192 Query: 723 HYSIKGGDDSNSFSLETRQG----SDKAELVTMVDLDYESPRKKYELVIRA---ASPPLW 775 Y I G+ N F L T + L T +LD ES R Y+L I A SPP + Sbjct: 193 QYEIVAGNVDNKFRLVTTANPSGDTSYLHLETTGNLDRES-RGSYQLNISARDGGSPPRF 251 Query: 776 NDVRVEILVTDVNDNAPVM--KDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILS 833 ++V + + DVNDN P+ D+ + N + P P V A D D+ D + Sbjct: 252 GYLQVNVTILDVNDNPPIFDHSDYNVSLN--ETALPGTPVVTVMASDNDLGDNSKITYYL 309 Query: 834 GNNANLILLNETTGSMTLSPQLN----TNVPKLATMEVSV 869 + +N TG ++ + ++N TNV A+ + V Sbjct: 310 AETEHQFTVNPETGVISTTERVNCPQQTNVKSSASQKSCV 349 Score = 91.9 bits (218), Expect = 2e-16 Identities = 98/332 (29%), Positives = 138/332 (41%), Gaps = 55/332 (16%) Query: 1040 TSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYT 1099 +S+ C C GF G CE++ SC + C G CV+ + G C+ Sbjct: 4074 SSYFCLCRPGFRGNQCESV--SDSCRPNP----CLHGGLCVSLKPG----YKCNCTPGRY 4123 Query: 1100 TAVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYN--GRYNERHDFLAL 1157 CE + F S++TFP L + + FAT + LLLYN + R DFLA+ Sbjct: 4124 GRHCERFSYGFQPLSYMTFPALDVTTN-DISIVFATTKPNSLLLYNYGMQSGGRSDFLAI 4182 Query: 1158 ELVSSEAGRGGGPGLRFSFSLGGGKSEIT--VEG-NVGDGSWHTVEIEYFNRTITMILDD 1214 ELV A FS GG ++ I+ + G N+ DG WH V R ++ Sbjct: 4183 ELVHGRA----------YFSSGGARTAISTVIAGRNLADGGWHKVTATRNGRVMS----- 4227 Query: 1215 CDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLT---GPLQIGGL---- 1267 LS+A AD G + + LP + L PL IGGL Sbjct: 4228 ----LSVAKCADSG------DVCTECLPGDSSCYADEVGPVGTLNFNKQPLMIGGLSSAD 4277 Query: 1268 PNIPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSA----PCY 1323 P + QV + D VGC+ +I + ++L+ + G LAGC R C A C Sbjct: 4278 PILERPGQVHSDDLVGCLHSVHIGGRALNLSLPLQQKGILAGC--NRQACQPALAAERCG 4335 Query: 1324 NGA-ECSDLWDTYICDCKEGHTGKDCADSTGP 1354 A +C D W + +C C DC+DS P Sbjct: 4336 GFAGQCIDRWSSSLCQCGGHLQSPDCSDSLEP 4367 Score = 49.6 bits (113), Expect = 0.001 Identities = 64/281 (22%), Positives = 109/281 (38%), Gaps = 40/281 (14%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC----------ADSTGPPWRFG 1359 C C PC +G C L Y C+C G G+ C + T P Sbjct: 4089 CESVSDSCRPNPCLHGGLCVSLKPGYKCNCTPGRYGRHCERFSYGFQPLSYMTFPALDVT 4148 Query: 1360 GDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVMSIQLKSGLLHYSYNGETMYLPMA--- 1416 + + +P L N +++ R F ++I+L G ++S G + Sbjct: 4149 TNDISIVFATTKPNSLLLYN-YGMQSGGRSDF-LAIELVHGRAYFSSGGARTAISTVIAG 4206 Query: 1417 -TLSDGAWHRIEIKWLGTDISVTV----DYG-LRTVLMPMLANKIQGQY--IGKI----- 1463 L+DG WH++ G +S++V D G + T +P ++ + +G + Sbjct: 4207 RNLADGGWHKVTATRNGRVMSLSVAKCADSGDVCTECLPGDSSCYADEVGPVGTLNFNKQ 4266 Query: 1464 --LIGGLDTTAGLLASDVGFFE----GCIQDVRIGTAQSLLNRPTVRENVRDGCQSRADC 1517 +IGGL + +L GC+ V IG L+ P ++ + GC +A C Sbjct: 4267 PLMIGGLSSADPILERPGQVHSDDLVGCLHSVHIGGRALNLSLPLQQKGILAGCNRQA-C 4325 Query: 1518 MLSI----CPPYS-KCVTSWDSSTCTCEAGRVGPQCVSACE 1553 ++ C ++ +C+ W SS C C P C + E Sbjct: 4326 QPALAAERCGGFAGQCIDRWSSSLCQCGGHLQSPDCSDSLE 4366 Score = 36.7 bits (81), Expect = 9.2 Identities = 30/81 (37%), Positives = 34/81 (41%), Gaps = 12/81 (14%) Query: 1508 RDG--CQS-RAD-CMLSICPPYSKCVTSWDSST--CTCEAGRVGPQCVS---ACELGPC- 1557 RDG C+ R+D C C C S D S+ C C G G QC S +C PC Sbjct: 4043 RDGKHCEKERSDVCYSKPCRNGGSCQRSPDGSSYFCLCRPGFRGNQCESVSDSCRPNPCL 4102 Query: 1558 GAARCVPDQTPKGYSCACEPG 1578 CV GY C C PG Sbjct: 4103 HGGLCV--SLKPGYKCNCTPG 4121 Score = 36.7 bits (81), Expect = 9.2 Identities = 23/58 (39%), Positives = 28/58 (48%), Gaps = 7/58 (12%) Query: 1310 CPEKRSR-CSSAPCYNGAECSDLWD--TYICDCKEGHTGKDC---ADSTGP-PWRFGG 1360 C ++RS C S PC NG C D +Y C C+ G G C +DS P P GG Sbjct: 4048 CEKERSDVCYSKPCRNGGSCQRSPDGSSYFCLCRPGFRGNQCESVSDSCRPNPCLHGG 4105 >UniRef50_UPI0000E49AEF Cluster: PREDICTED: similar to Fat4; n=5; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to Fat4 - Strongylocentrotus purpuratus Length = 4601 Score = 339 bits (834), Expect = 5e-91 Identities = 256/801 (31%), Positives = 386/801 (48%), Gaps = 67/801 (8%) Query: 11 INVLDCNDHSPVFEMQQ----YEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 + V D ND++PVF + Y S+ E +GT ++ + TD D G NA V Y+I Sbjct: 936 VTVTDVNDNNPVFINRPIDNIYRGSINENDQTGTFIVQVSTTDADSGSNAAVTYSI---- 991 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 + +VF I+ SGA+ L YT+ V+AT+ V Sbjct: 992 ---------------ISGNINNVFTINPTSGAITNTQILGPNTPQTYTLSVRATNPTPGV 1036 Query: 127 SDRL-SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 + +ST+T+ + + D ND+ P+FS+ +TV ++E V + +I ATD D+ Sbjct: 1037 APATGTSTSTVIITVNDVNDSPPRFSDDEFTVFINEAAQV--GTTVTRITATDEDIPEGD 1094 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 + Y I GNT F I+ +SGDV+L++ LD E + L IRA D G+P +S TT L + Sbjct: 1095 RLTYIITAGNTGGHFQINPVSGDVTLLRQLDRELESQHNLTIRATDQGAPPQSATTTLKV 1154 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 + D NDNAP++ + +S+ ENVP+ +++V A DAD+G NA+L++T+ + + Sbjct: 1155 IVLDFNDNAPQWSPQSYVDSILENVPLNTFVLQVVATDADQGTNADLSFTINNAN----- 1209 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT--ATXXXXXXXXXXXX 363 ++P ID + G + TSG L+RET +Y LVT D G P ++ AT Sbjct: 1210 NVPFVIDDQ-GNIRTSGPLNRETVPQYNFLVTVLDNGSPQQAGNPPATVTINILDVNDEP 1268 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423 YE ++ED T V +TATD D L Y + FS S G I Sbjct: 1269 PVLDRNSYEFTVSEDVNFNTFVGQVTATDPDLSGTLTYTFVPADP--DFSYIS----GTI 1322 Query: 424 TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 LD Q++ Y +TV A+D S +A V IN+ D NN AP F Y S+ ED+P Sbjct: 1323 RTNTQLDANQQQVYQMTVFASDGVQNSQSAPVTINVLDVNNQAPSFGLGTYVKSLPEDSP 1382 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA--ITTNKLLDR 541 T V+ ++ATD D G I YS E+++ F ++P TG I+T LDR Sbjct: 1383 FQTLVVDLNATDPDNGNTGLIIYSF------ESLSRTQGPFTVDPYTGVVEISTTAGLDR 1436 Query: 542 ETMSGYLLTVTARD---GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 ET Y + V A D G P ++ T V + V DVNDN P F+ Y +I E+ +G+ Sbjct: 1437 ETQDEYTMIVIAVDQPASGQP-MTGTATVSVIVTDVNDNAPTFRDISYEESIFENHPLGS 1495 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 ++ V A D D+G+N + Y + F +D + + LDRE + L Sbjct: 1496 NILTVQADDPDLGVNAVVLYRI-ISGNNNNLFNVDGQGNINLGSTPLDREMQDQYFLIVQ 1554 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY---ISENSPIGTTIGEIRAHDPD 715 A + ++ V V I I DIND P+F+ +Y +SENSP GT + ++ A D D Sbjct: 1555 AYNSDLSVGTNEVPVIINILDINDVTPLFQQQ--NYYRPDLSENSPSGTPVLQVFAQDQD 1612 Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASP 772 V YS+ G + + + +T S + + S + + + +RA ASP Sbjct: 1613 LDLAGDVQYSLIGNPNFLTINSDTGVISVNGPIADL------SGSRNFTMTVRATDQASP 1666 Query: 773 PLWNDVRVEILVTDVNDNAPV 793 L V + V D P+ Sbjct: 1667 FLRGVATVTVTVVDDTVTIPI 1687 Score = 331 bits (813), Expect = 2e-88 Identities = 268/862 (31%), Positives = 415/862 (48%), Gaps = 88/862 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 ++VL+ D +PVF Y+ ++ E G+TV T+ ATD D + Y LV +D+ Sbjct: 719 VSVLNIQDTNPVFINTPYDVTIPETLPVGSTVQTITATDPDSNDGNIITYN--LVVSDS- 775 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKV---ARYTVLVKATDQASPVS 127 Q F ID +G + + +DR+ A Y ++V A + +S Sbjct: 776 ----------------QGYFVIDQTTGIITVNSQMDRDNPVLPATYPLIVSAVETSS--G 817 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 + + +V + ND P F + +Y+ S+ E SV I I D D+ +S + Sbjct: 818 GVSFAQVSFNVTVSPANDEPPMFDQNSYSASIPESASVNSQLPIT-ITVNDGDLITDSTV 876 Query: 188 RYAIIGGNT-QMQFSIDSLSG----DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 ++ GN+ + S + G D+ + + LD+E + Y L ++A DG + Sbjct: 877 TVSLQNGNSVPFRVSPTQVVGSGTVDILITQPLDFENNQQYTLQLQAVDGDG---QDIAP 933 Query: 243 LLINIRDVNDNAPRFYT----SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 L++ + DVNDN P F ++++ S++EN G IV+V DAD G NA +TY++ Sbjct: 934 LMVTVTDVNDNNPVFINRPIDNIYRGSINENDQTGTFIVQVSTTDADSGSNAAVTYSII- 992 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG--GDPPRSATATXXXXX 356 +GN++ TI+P SG + + L T Y L V AT+ G P + T+T Sbjct: 993 ---SGNINNVFTINPTSGAITNTQILGPNTPQTYTLSVRATNPTPGVAPATGTSTSTVII 1049 Query: 357 XXXXXXXX--XFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRF 412 F ++ V + E GT V +TATD D E +RL Y IT GNT G F Sbjct: 1050 TVNDVNDSPPRFSDDEFTVFINEAAQVGTTVTRITATDEDIPEGDRLTYIITAGNTGGHF 1109 Query: 413 SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFE 470 I +G +T+ + LD + E ++ LT+ ATD G +S T +++ + D N+ AP + Sbjct: 1110 QINPVSGD--VTLLRQLDRELESQHNLTIRATDQGAPPQSATTTLKVIVLDFNDNAPQWS 1167 Query: 471 NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 Y S+ E+ P+ T VL V ATD+D G NA +++++++ ++ FVI+ Q Sbjct: 1168 PQSYVDSILENVPLNTFVLQVVATDADQGTNADLSFTINNA--------NNVPFVIDDQ- 1218 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT--TDVEISVVDVNDNEPVFKQQLYTA 588 G I T+ L+RET+ Y VT D G P + V I+++DVND PV + Y Sbjct: 1219 GNIRTSGPLNRETVPQYNFLVTVLDNGSPQQAGNPPATVTINILDVNDEPPVLDRNSYEF 1278 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648 + ED T V QV ATD D L+G + Y P D + S++ SG IRTN LD Sbjct: 1279 TVSEDVNFNTFVGQVTATDPD--LSGTLTYTFVPAD-PDFSYI----SGTIRTNTQLDAN 1331 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 + + A DG QS+ V +++ D+N+ P F + E+SP T + + Sbjct: 1332 QQQVYQMTVFASDGVQNSQSAPVTINVL--DVNNQAPSFGLGTYVKSLPEDSPFQTLVVD 1389 Query: 709 IRAHDPDEGPNAVVHYSIKG-GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 + A DPD G ++ YS + F+++ G E+ T LD E+ + +VI Sbjct: 1390 LNATDPDNGNTGLIIYSFESLSRTQGPFTVDPYTGV--VEISTTAGLDRETQDEYTMIVI 1447 Query: 768 RAASP----PLWNDVRVEILVTDVNDNAPVMKDF---QIIFNNYKDCFPVGP-FGRVPAY 819 P P+ V ++VTDVNDNAP +D + IF N+ P+G V A Sbjct: 1448 AVDQPASGQPMTGTATVSVIVTDVNDNAPTFRDISYEESIFENH----PLGSNILTVQAD 1503 Query: 820 DAD--VTDKLQYRILSGNNANL 839 D D V + YRI+SGNN NL Sbjct: 1504 DPDLGVNAVVLYRIISGNNNNL 1525 Score = 293 bits (720), Expect = 3e-77 Identities = 263/888 (29%), Positives = 406/888 (45%), Gaps = 81/888 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ VLD ND++P + Q Y S+ E T VL + ATD D G NA++ +TI A+ Sbjct: 1153 KVIVLDFNDNAPQWSPQSYVDSILENVPLNTFVLQVVATDADQGTNADLSFTIN--NANN 1210 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + F ID + G + T L+RE V +Y LV D SP Sbjct: 1211 V------------------PFVIDDQ-GNIRTSGPLNRETVPQYNFLVTVLDNGSP-QQA 1250 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + AT+ +NI+D ND P +Y +V ED++ N + ++ ATD D+ + + Y Sbjct: 1251 GNPPATVTINILDVNDEPPVLDRNSYEFTVSEDVNF--NTFVGQVTATDPDL--SGTLTY 1306 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 + + + +SG + LD Q + Y++ + A DG S+S + IN+ D Sbjct: 1307 TFVPADPDFSY----ISGTIRTNTQLDANQQQVYQMTVFASDGVQNSQS--APVTINVLD 1360 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 VN+ AP F + +S+ E+ P +V + A D D G + Y+ T P Sbjct: 1361 VNNQAPSFGLGTYVKSLPEDSPFQTLVVDLNATDPDNGNTGLIIYSFESLSRTQG---PF 1417 Query: 310 TIDPRSGWV--YTSGQLDRETQAKYQLLVTATD--GGDPPRSATATXXXXXXXXXXXXXX 365 T+DP +G V T+ LDRETQ +Y ++V A D P + TAT Sbjct: 1418 TVDPYTGVVEISTTAGLDRETQDEYTMIVIAVDQPASGQPMTGTATVSVIVTDVNDNAPT 1477 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLI 423 F YE + E+ P G+ ++T+ A D D + + Y I GN F++ +G+G I Sbjct: 1478 FRDISYEESIFENHPLGSNILTVQADDPDLGVNAVVLYRIISGNNNNLFNV---DGQGNI 1534 Query: 424 TV-AQPLDFKQERRYVLTVSA--TDSGGRSDTAMVQINITDANNYAPVFENAP-YTASVF 479 + + PLD + + +Y L V A +D ++ V INI D N+ P+F+ Y + Sbjct: 1535 NLGSTPLDREMQDQYFLIVQAYNSDLSVGTNEVPVIINILDINDVTPLFQQQNYYRPDLS 1594 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN-KL 538 E++P GT VL V A D D+ + + YSL I N IN TG I+ N + Sbjct: 1595 ENSPSGTPVLQVFAQDQDLDLAGDVQYSL---IGN------PNFLTINSDTGVISVNGPI 1645 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 D + +TV A D P L V ++VVD P+F Y A ++E+ T Sbjct: 1646 ADLSGSRNFTMTVRATDQASPFLRGVATVTVTVVDDTVTIPIFTLSRYPATVIENVNADT 1705 Query: 599 SVSQVGATDADVGLNGR---IHYELDPKDREE--GSFVIDPASGVIRTNKALDRESVATH 653 V++V AT LNG I Y +DP F ID +G I T A+DRE + Sbjct: 1706 PVTRVSAT-----LNGNPAGITYAIDPNASPAVLEIFKIDENTGHITTEGAIDREVEDFY 1760 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES-DCLTFYISENSPIGTTIGEIRAH 712 A + ST V + I D ND+PP F + + EN+ +G RA Sbjct: 1761 AFTVFAYHEDSVAPGST-SVWVNILDENDNPPEFITVPPSPVSVRENTGGNVPVGLFRAT 1819 Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSL-ETRQGSDKAELVTMVDLDYESPRKKYELVIRA-- 769 DPD G NA + +SI G SN F++ +T G +V LD E + Y+L + A Sbjct: 1820 DPDAGINAQMTFSISGA-GSNFFNVFQTANGG--GTIVVTSPLDRER-QDFYQLTVTATD 1875 Query: 770 -ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDK 826 +P L + + I VTDVNDN P+ + ++ F P V D D+ ++ Sbjct: 1876 GGNPSLSSSFPLNITVTDVNDNYPIWTRNVYEGSINENNFTSNPIITVMVNDLDLPSSNN 1935 Query: 827 LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN 874 +Y I++G+ + +N + G +T+S L+ + + + + D N Sbjct: 1936 FEYSIIAGDPMGMFEIN-SNGEITVSSLLDREQQETYQLTIELIDQTN 1982 Score = 291 bits (715), Expect = 1e-76 Identities = 243/799 (30%), Positives = 368/799 (46%), Gaps = 58/799 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 INVLD N+ +P F + Y S+ E + T V+ L ATD D G + Y+ E ++ Sbjct: 1356 INVLDVNNQAPSFGLGTYVKSLPEDSPFQTLVVDLNATDPDNGNTGLIIYSFESLSR--- 1412 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGA--LLTRASLDREKVARYTVLVKATDQASPVSD 128 Q F +D +G + T A LDRE YT++V A DQ P S Sbjct: 1413 ---------------TQGPFTVDPYTGVVEISTTAGLDRETQDEYTMIVIAVDQ--PASG 1455 Query: 129 R-LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 + ++ TAT+ V + D NDN P F + +Y S+ E+ + N I ++A D D+G N+ + Sbjct: 1456 QPMTGTATVSVIVTDVNDNAPTFRDISYEESIFENHPLGSN--ILTVQADDPDLGVNAVV 1513 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 Y II GN F++D G+++L T LD E Y L+++A + +N ++IN Sbjct: 1514 LYRIISGNNNNLFNVDG-QGNINLGSTPLDREMQDQYFLIVQAYNSDLSVGTNEVPVIIN 1572 Query: 247 IRDVNDNAPRFYT-SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 I D+ND P F + ++ +SEN P G +++V A D D + ++ Y++ GN Sbjct: 1573 ILDINDVTPLFQQQNYYRPDLSENSPSGTPVLQVFAQDQDLDLAGDVQYSLI-----GNP 1627 Query: 306 DLPITIDPRSGWVYTSGQL-DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 + +TI+ +G + +G + D + + V ATD P AT Sbjct: 1628 NF-LTINSDTGVISVNGPIADLSGSRNFTMTVRATDQASPFLRGVATVTVTVVDDTVTIP 1686 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITS-QNGRGLI 423 F +Y + E+ TPV ++AT + Y I + I G I Sbjct: 1687 IFTLSRYPATVIENVNADTPVTRVSATLNGNPAGITYAIDPNASPAVLEIFKIDENTGHI 1746 Query: 424 TVAQPLDFKQERRYVLTVSA--TDSGGRSDTAMVQINITDANNYAPVFENAPYT-ASVFE 480 T +D + E Y TV A DS T+ V +NI D N+ P F P + SV E Sbjct: 1747 TTEGAIDREVEDFYAFTVFAYHEDSVAPGSTS-VWVNILDENDNPPEFITVPPSPVSVRE 1805 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 + V + ATD D GINAQ+T+S+S SN F G I LD Sbjct: 1806 NTGGNVPVGLFRATDPDAGINAQMTFSISGAGSN-----FFNVFQTANGGGTIVVTSPLD 1860 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 RE Y LTVTA DGG PSLS + + I+V DVNDN P++ + +Y +I E+ + Sbjct: 1861 RERQDFYQLTVTATDGGNPSLSSSFPLNITVTDVNDNYPIWTRNVYEGSINENNFTSNPI 1920 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 V D D+ + Y + D G F I+ ++G I + LDRE T+ L I Sbjct: 1921 ITVMVNDLDLPSSNNFEYSIIAGD-PMGMFEIN-SNGEITVSSLLDREQQETYQLTIELI 1978 Query: 661 D-GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN-SPIGTTIGEIRAHDPDEGP 718 D +PP +T + I + D ND+ P+F + ++E S + + A+D D G Sbjct: 1979 DQTNSPPARTTTLAIITVGDENDNTPIFAETVIRVDVTEGPSSQNIPVYMLTANDIDLGL 2038 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA--SP--PL 774 N + Y+I + F + G + T LD+E+ +Y L++ A SP P Sbjct: 2039 NRDIIYAIGSQQPQSHFQINPETGM----ISTTTALDWET-ISEYTLIVTATDQSPTEPR 2093 Query: 775 WNDVRVEILVTDVNDNAPV 793 V + V D+ND AP+ Sbjct: 2094 TGTATVIVSVNDINDGAPM 2112 Score = 289 bits (708), Expect = 1e-75 Identities = 236/752 (31%), Positives = 343/752 (45%), Gaps = 78/752 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTADT 69 + V D NDH+P F QY +V E GT V + D D + + ++ YTI +T + Sbjct: 3244 VTVTDANDHNPTFVPDQYSLTVTENEPPGTQVGAVITIDGDTLPEYTDIIYTI--LTGNG 3301 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L F I+ +G + T LDREK + Y + + A + PV Sbjct: 3302 LGN-----------------FTINSTTGIITTATILDREKTSEYVLTIGAEN---PVGGT 3341 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + TAT+ + + D NDN P F E Y +S +VT N ++ + A D D G N + Y Sbjct: 3342 -TGTATVSIIVRDVNDNTPTFEENPY-IS-----TVTTNTLLVDVHANDPDEGGNGIVIY 3394 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I+ GN +F ID+ +G ++LV LD + +R+Y LV+ D G+P + T + + I Sbjct: 3395 EIVSGNEDNRFQIDNRTGVITLVNPLDSQLIRNYTLVVIGHDLGNPRLQSNTTVDLRINY 3454 Query: 250 VNDNAPRFYTSLFQES---VSENVPIGYSIVRVQAYDADEGVNAELTYT-MTDKDYTGNV 305 + NAP + Q S ++EN P+G I+ A D D G N + Y+ + + DY G + Sbjct: 3455 LGLNAPPSFVRPNQGSTVFITENNPLGQLIINAFAVDDDVGANGVVDYSILPNFDYNGGL 3514 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 I + P LD ET Y L V TD D T Sbjct: 3515 ---IPVKP----------LDFETFTNYNLTVVVTD--DSGNRDTTYVAVTVTDANDHNPT 3559 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQNGRGL 422 F+P QY + + E+EPPGT V + D D E + Y I GN G F+I S G+ Sbjct: 3560 FVPDQYSLTVTENEPPGTQVGVVITIDGDTLPEYTDIIYTILTGNGLGNFTINSTT--GI 3617 Query: 423 ITVAQPLDFKQERRYVLTVSATDS-GGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 IT A LD ++ YVLT+ A + GG + TA V I + D N+ P FE PYT++V Sbjct: 3618 ITTATILDREKTSEYVLTIGAENPVGGTTGTATVSIIVRDVNDNTPTFEENPYTSTV--- 3674 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 T ++ V A D D G N + Y + S NE D +F I+ +TG IT L+ Sbjct: 3675 -TTNTLLVDVHANDPDEGGNGIVIYEIVS--GNE-----DNRFTIDNRTGVITLVNPLES 3726 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP---VFKQQLYTANIMEDALVGT 598 + + Y L V D G P L T V++ + + N P V Q T I E+ +G Sbjct: 3727 QLIRNYTLVVIGHDLGNPQLQSNTTVDLRINYLGLNAPPSFVRPNQGSTVFITENNPLGL 3786 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 + A D DVG NG + Y + P + + F IDP +G I + DRE ++ L V Sbjct: 3787 LIINAFAVDDDVGANGVVDYSILP-NFDYSDFTIDPVTGDITILVSADREIKDSYTLTVV 3845 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESD-------CLTFYISENSPIGTTIGEI-R 710 A D G P S++ I++ D ND+ P F L + EN+ I +G + Sbjct: 3846 ATDRGDPNLSTSSTFVIRVLDENDNNPAFPRPDGMNNPIVLNLNVFENANISDLVGTVDG 3905 Query: 711 AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 A D D G N + Y I F + + G Sbjct: 3906 AIDLDLGANGQIFYHIVDSTVGGIFVINSTTG 3937 Score = 283 bits (695), Expect = 4e-74 Identities = 242/857 (28%), Positives = 397/857 (46%), Gaps = 63/857 (7%) Query: 61 TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVL-VKA 119 +I + T + +P+ + +F I+ +G L LD E + ++ V Sbjct: 532 SILVFTLNATDPDGDPITYDLFDDEARSIFTINQFTGQLYALPGLDYETLGNQVIITVSV 591 Query: 120 TDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA 179 TD ++D + T I+V I D ND P F+ V E+ T + ++ TD Sbjct: 592 TDG---INDPVPQT--IYVRITDVNDIAPTFTNLPNITYVFEN--ATFGSELYQVITTDE 644 Query: 180 DVGANSAIRYAII-------GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232 D + Y+I G FSI G + L +L+YE+++ Y + + A+D Sbjct: 645 DTFYGGFVTYSISLVTPSTPGSAPNNYFSIGETDGIIQLATSLNYEEIQQYFVTVVARDY 704 Query: 233 GS--PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290 G+ S S+T L +++ ++ D P F + + ++ E +P+G ++ + A D D Sbjct: 705 GTGDTSLSSTATLTVSVLNIQDTNPVFINTPYDVTIPETLPVGSTVQTITATDPDSNDGN 764 Query: 291 ELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET---QAKYQLLVTATDGGDPPRS 347 +TY + D G ID +G + + Q+DR+ A Y L+V+A + S Sbjct: 765 IITYNLVVSDSQGY----FVIDQTTGIITVNSQMDRDNPVLPATYPLIVSAVETSSGGVS 820 Query: 348 -ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV-VTLTATDAD--EDNRLHYEI 403 A + F Y + E + + +T+T D D D+ + + Sbjct: 821 FAQVSFNVTVSPANDEPPMFDQNSYSASIPESASVNSQLPITITVNDGDLITDSTVTVSL 880 Query: 404 TGGNT-RGRFSITSQNGRGL--ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT 460 GN+ R S T G G I + QPLDF+ ++Y L + A D G+ D A + + +T Sbjct: 881 QNGNSVPFRVSPTQVVGSGTVDILITQPLDFENNQQYTLQLQAVDGDGQ-DIAPLMVTVT 939 Query: 461 DANNYAPVFENAP----YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA 516 D N+ PVF N P Y S+ E+ GT ++ VS TD+D G NA +TYS+ S N Sbjct: 940 DVNDNNPVFINRPIDNIYRGSINENDQTGTFIVQVSTTDADSGSNAAVTYSIISGNINNV 999 Query: 517 VAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD---GGVPSL-SDTTDVEISVV 572 F INP +GAIT ++L T Y L+V A + G P+ + T+ V I+V Sbjct: 1000 -------FTINPTSGAITNTQILGPNTPQTYTLSVRATNPTPGVAPATGTSTSTVIITVN 1052 Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632 DVND+ P F +T I E A VGT+V+++ ATD D+ R+ Y + G F I Sbjct: 1053 DVNDSPPRFSDDEFTVFINEAAQVGTTVTRITATDEDIPEGDRLTY-IITAGNTGGHFQI 1111 Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692 +P SG + + LDRE + H+L A D G PPQS+T + + + D ND+ P + Sbjct: 1112 NPVSGDVTLLRQLDRELESQHNLTIRATDQGAPPQSATTTLKVIVLDFNDNAPQWSPQSY 1171 Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752 I EN P+ T + ++ A D D+G NA + ++I ++ F ++ D+ + T Sbjct: 1172 VDSILENVPLNTFVLQVVATDADQGTNADLSFTINNANNV-PFVID-----DQGNIRTSG 1225 Query: 753 DLDYES-PRKKYEL-VIRAASPPLWND--VRVEILVTDVNDNAPVMKDFQIIFNNYKDCF 808 L+ E+ P+ + + V+ SP + V I + DVND PV+ F +D Sbjct: 1226 PLNRETVPQYNFLVTVLDNGSPQQAGNPPATVTINILDVNDEPPVLDRNSYEFTVSEDVN 1285 Query: 809 PVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVS 868 G+V A D D++ L Y + + + +G++ + QL+ N ++ M V Sbjct: 1286 FNTFVGQVTATDPDLSGTLTYTFVPADPD----FSYISGTIRTNTQLDANQQQVYQMTVF 1341 Query: 869 VTDGV-NEIKAMMQLSV 884 +DGV N A + ++V Sbjct: 1342 ASDGVQNSQSAPVTINV 1358 Score = 266 bits (651), Expect = 8e-69 Identities = 261/885 (29%), Positives = 391/885 (44%), Gaps = 93/885 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D ND+ P F++ Y+ +V EG S ++T+ A D D +N+ + Y I L Sbjct: 3146 IYINDLNDNQPTFDLPLYDVTVVEGQYSDP-IITVVANDPD--QNSNLRYEI---LGGNL 3199 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N +DG L+ LD E Y + V TD + Sbjct: 3200 N---------------NTFVLVDG---GLIPVKPLDFETFTNYNLTVVVTDDSGN----- 3236 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 T + V + D ND+ P F Y+++V E+ V A I + + I Y Sbjct: 3237 RDTTYVAVTVTDANDHNPTFVPDQYSLTVTEN-EPPGTQVGAVITIDGDTLPEYTDIIYT 3295 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD--GGSPSRSNTTQLLINIR 248 I+ GN F+I+S +G ++ LD E+ Y L I A++ GG+ + T + I +R Sbjct: 3296 ILTGNGLGNFTINSTTGIITTATILDREKTSEYVLTIGAENPVGGT---TGTATVSIIVR 3352 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 DVNDN P F + + +V+ N +V V A D DEG N + Y + +GN D Sbjct: 3353 DVNDNTPTFEENPYISTVTTNT----LLVDVHANDPDEGGNGIVIYEIV----SGNEDNR 3404 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP-RSATATXXXXXXXXXXXXXXFM 367 ID R+G + LD + Y L+V D G+P +S T F+ Sbjct: 3405 FQIDNRTGVITLVNPLDSQLIRNYTLVVIGHDLGNPRLQSNTTVDLRINYLGLNAPPSFV 3464 Query: 368 -PGQYE-VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ---NGRGL 422 P Q V + E+ P G ++ A D D G N +SI NG GL Sbjct: 3465 RPNQGSTVFITENNPLGQLIINAFAVDDD---------VGANGVVDYSILPNFDYNG-GL 3514 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 I V +PLDF+ Y LTV TD G DT V + +TDAN++ P F Y+ +V E+ Sbjct: 3515 IPV-KPLDFETFTNYNLTVVVTDDSGNRDTTYVAVTVTDANDHNPTFVPDQYSLTVTENE 3573 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 P GT V VV D D + T + + ++ + + F IN TG ITT +LDRE Sbjct: 3574 PPGTQVGVVITIDGDT--LPEYTDIIYTILTGNGLGN----FTINSTTGIITTATILDRE 3627 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 S Y+LT+ A + V + T V I V DVNDN P F++ YT+ + + L+ Sbjct: 3628 KTSEYVLTIGA-ENPVGGTTGTATVSIIVRDVNDNTPTFEENPYTSTVTTNTLL----VD 3682 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 V A D D G NG + YE+ E+ F ID +GVI L+ + + + L + D Sbjct: 3683 VHANDPDEGGNGIVIYEI-VSGNEDNRFTIDNRTGVITLVNPLESQLIRNYTLVVIGHDL 3741 Query: 663 GTPPQSSTVIVHIKIEDIN-DSPPVF--ESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 G P S V ++I + ++PP F + T +I+EN+P+G I A D D G N Sbjct: 3742 GNPQLQSNTTVDLRINYLGLNAPPSFVRPNQGSTVFITENNPLGLLIINAFAVDDDVGAN 3801 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWN 776 VV YSI D + F+++ G ++ +V D E + Y L + A P L Sbjct: 3802 GVVDYSILPNFDYSDFTIDPVTG----DITILVSADREI-KDSYTLTVVATDRGDPNLST 3856 Query: 777 DVRVEILVTDVNDNAPV------MKDFQI----IFNNYKDCFPVGPFGRVPAYDADVTDK 826 I V D NDN P M + + +F N VG D + Sbjct: 3857 SSTFVIRVLDENDNNPAFPRPDGMNNPIVLNLNVFENANISDLVGTVDGAIDLDLGANGQ 3916 Query: 827 LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + Y I+ + ++N TTG +T++ L+ + T+ + T+ Sbjct: 3917 IFYHIVDSTVGGIFVINSTTGVVTVNGTLDREDIGVHTIYILATN 3961 Score = 264 bits (647), Expect = 2e-68 Identities = 247/888 (27%), Positives = 397/888 (44%), Gaps = 81/888 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND +P F V E A+ G+ + + TD+D V Y+I LVT T Sbjct: 605 VRITDVNDIAPTFTNLPNITYVFENATFGSELYQVITTDEDTFYGGFVTYSISLVTPST- 663 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P A + F I G + SL+ E++ +Y V V A D + L Sbjct: 664 -PGSA----------PNNYFSIGETDGIIQLATSLNYEEIQQYFVTVVARDYGTG-DTSL 711 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SSTAT+ V++++ D P F Y V++ E + V + I ATD D + I Y Sbjct: 712 SSTATLTVSVLNIQDTNPVFINTPYDVTIPETLPV--GSTVQTITATDPDSNDGNIITYN 769 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQ---VRSYRLVIRAQDGGSPSRS-NTTQLLIN 246 ++ ++Q F ID +G +++ +D + +Y L++ A + S S + Sbjct: 770 LVVSDSQGYFVIDQTTGIITVNSQMDRDNPVLPATYPLIVSAVETSSGGVSFAQVSFNVT 829 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSI-VRVQAYDADEGVNAELTYTMTDKDYTGNV 305 + ND P F + + S+ E+ + + + + D D ++ +T ++ + GN Sbjct: 830 VSPANDEPPMFDQNSYSASIPESASVNSQLPITITVNDGDLITDSTVTVSLQN----GN- 884 Query: 306 DLPITIDPR----SGWV--YTSGQLDRETQAKYQLLVTATDG-GDPPRSATATXXXXXXX 358 +P + P SG V + LD E +Y L + A DG G T Sbjct: 885 SVPFRVSPTQVVGSGTVDILITQPLDFENNQQYTLQLQAVDGDGQDIAPLMVTVTDVNDN 944 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITS 416 + Y + E++ GT +V ++ TDAD + + Y I GN F+I Sbjct: 945 NPVFINRPIDNIYRGSINENDQTGTFIVQVSTTDADSGSNAAVTYSIISGNINNVFTINP 1004 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATD------SGGRSDTAMVQINITDANNYAPVFE 470 + G IT Q L + Y L+V AT+ + T+ V I + D N+ P F Sbjct: 1005 TS--GAITNTQILGPNTPQTYTLSVRATNPTPGVAPATGTSTSTVIITVNDVNDSPPRFS 1062 Query: 471 NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 + +T + E A +GTTV ++ATD D+ ++TY +++ + F INP + Sbjct: 1063 DDEFTVFINEAAQVGTTVTRITATDEDIPEGDRLTYIITA-------GNTGGHFQINPVS 1115 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590 G +T + LDRE S + LT+ A D G P S TT +++ V+D NDN P + Q Y +I Sbjct: 1116 GDVTLLRQLDRELESQHNLTIRATDQGAPPQSATTTLKVIVLDFNDNAPQWSPQSYVDSI 1175 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650 +E+ + T V QV ATDAD G N + + ++ + FVID G IRT+ L+RE+V Sbjct: 1176 LENVPLNTFVLQVVATDADQGTNADLSFTIN--NANNVPFVIDD-QGNIRTSGPLNRETV 1232 Query: 651 ATHDLKAVAIDGGTPPQSST--VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 ++ +D G+P Q+ V I I D+ND PPV + + F +SE+ T +G+ Sbjct: 1233 PQYNFLVTVLDNGSPQQAGNPPATVTINILDVNDEPPVLDRNSYEFTVSEDVNFNTFVGQ 1292 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768 + A DPD + + Y+ D S+ T + T LD + ++ Y++ + Sbjct: 1293 VTATDPD--LSGTLTYTFVPADPDFSYISGT--------IRTNTQLD-ANQQQVYQMTV- 1340 Query: 769 AASPPLWN--DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK 826 AS + N V I V DVN+ AP F + Y P + D + TD Sbjct: 1341 FASDGVQNSQSAPVTINVLDVNNQAP---SFGL--GTYVKSLPEDSPFQTLVVDLNATDP 1395 Query: 827 LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN 874 N LI+ + + S T P T P +E+S T G++ Sbjct: 1396 ------DNGNTGLIIYSFESLSRTQGP--FTVDPYTGVVEISTTAGLD 1435 Score = 261 bits (639), Expect = 2e-67 Identities = 247/875 (28%), Positives = 377/875 (43%), Gaps = 85/875 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + ++D ND++PVF Q + ++ E G V + ATD D G + V Y+ L+ D Sbjct: 2929 LEIIDNNDNNPVFGAQSHTTTIIESEPIGAFVFNVNATDADSGGSGRVTYS--LIGGD-- 2984 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F I+ SG + +D+E +++ + V A D D Sbjct: 2985 -----------------GKFTINQDSGVITLLQQVDKETQSQHMLTVFARDNPGDSEDSR 3027 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV--GANSAIR 188 + + T+ VN++D N+ P ++ +T+ D V+ I+A D D N ++ Sbjct: 3028 TGSTTVIVNVLDANEFPPVVTQPIFTI----DEGGIGGEVVGVIEAYDPDDPDDPNQSLY 3083 Query: 189 YAIIGGNTQMQ---FSIDSLSGDVSLVKTLDYEQ-VRSYR--LVIRAQDGGSPSRSNTTQ 242 Y ++ ++ F I++ +G++ LD + + R L + D G+P+ T Sbjct: 3084 YVVVSSQPEVGGTLFIINNATGEIITTGPLDRDNNLHPARVDLDVIVYDDGNPNLGTPTT 3143 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 +I I D+NDN P F L+ +V E I+ V A D D+ N+ L Y + Sbjct: 3144 AIIYINDLNDNQPTFDLPLYDVTVVEG-QYSDPIITVVANDPDQ--NSNLRYEILG---- 3196 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 GN++ + G + LD ET Y L V TD D T Sbjct: 3197 GNLNNTFVLV--DGGLIPVKPLDFETFTNYNLTVVVTD--DSGNRDTTYVAVTVTDANDH 3252 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQNG 419 F+P QY + + E+EPPGT V + D D E + Y I GN G F+I S G Sbjct: 3253 NPTFVPDQYSLTVTENEPPGTQVGAVITIDGDTLPEYTDIIYTILTGNGLGNFTINSTTG 3312 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDS-GGRSDTAMVQINITDANNYAPVFENAPYTASV 478 +IT A LD ++ YVLT+ A + GG + TA V I + D N+ P FE PY ++V Sbjct: 3313 --IITTATILDREKTSEYVLTIGAENPVGGTTGTATVSIIVRDVNDNTPTFEENPYISTV 3370 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 + T ++ V A D D G N + Y + S NE D +F I+ +TG IT Sbjct: 3371 TTN----TLLVDVHANDPDEGGNGIVIYEIVS--GNE-----DNRFQIDNRTGVITLVNP 3419 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP---VFKQQLYTANIMEDAL 595 LD + + Y L V D G P L T V++ + + N P V Q T I E+ Sbjct: 3420 LDSQLIRNYTLVVIGHDLGNPRLQSNTTVDLRINYLGLNAPPSFVRPNQGSTVFITENNP 3479 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655 +G + A D DVG NG + Y + P D G+I K LD E+ ++L Sbjct: 3480 LGQLIINAFAVDDDVGANGVVDYSILPN--------FDYNGGLIPV-KPLDFETFTNYNL 3530 Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 V D T V + + D ND P F D + ++EN P GT +G + D D Sbjct: 3531 TVVVTDDSG--NRDTTYVAVTVTDANDHNPTFVPDQYSLTVTENEPPGTQVGVVITIDGD 3588 Query: 716 EGPNAV-VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP- 773 P + Y+I G+ +F++ + G + T LD E +Y L I A +P Sbjct: 3589 TLPEYTDIIYTILTGNGLGNFTINSTTGI----ITTATILDREKT-SEYVLTIGAENPVG 3643 Query: 774 -LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRIL 832 V I+V DVNDN P ++ + V P D + Y I+ Sbjct: 3644 GTTGTATVSIIVRDVNDNTPTFEENPYTSTVTTNTLLVDVHANDP--DEGGNGIVIYEIV 3701 Query: 833 SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867 SGN N ++ TG +TL L + + + T+ V Sbjct: 3702 SGNEDNRFTIDNRTGVITLVNPLESQLIRNYTLVV 3736 Score = 257 bits (629), Expect = 4e-66 Identities = 249/881 (28%), Positives = 383/881 (43%), Gaps = 73/881 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 IN+LD ND PV + YE +V E + T V + ATD D+ + + YT V AD Sbjct: 1259 INILDVNDEPPVLDRNSYEFTVSEDVNFNTFVGQVTATDPDL--SGTLTYTF--VPAD-- 1312 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P+ + SG + T LD + Y + V A+D Sbjct: 1313 -PDFSYI------------------SGTIRTNTQLDANQQQVYQMTVFASDGVQN----- 1348 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S +A + +N++D N+ P F TY S+ ED ++ + ATD D G I Y+ Sbjct: 1349 SQSAPVTINVLDVNNQAPSFGLGTYVKSLPEDSPF--QTLVVDLNATDPDNGNTGLIIYS 1406 Query: 191 IIG-GNTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQD---GGSPSRSNTTQLL 244 TQ F++D +G V + T LD E Y +++ A D G P T + Sbjct: 1407 FESLSRTQGPFTVDPYTGVVEISTTAGLDRETQDEYTMIVIAVDQPASGQPMTGTATVSV 1466 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 I + DVNDNAP F ++ES+ EN P+G +I+ VQA D D GVNA + Y + +GN Sbjct: 1467 I-VTDVNDNAPTFRDISYEESIFENHPLGSNILTVQADDPDLGVNAVVLYRII----SGN 1521 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 + +D + S LDRE Q +Y L+V A + + Sbjct: 1522 NNNLFNVDGQGNINLGSTPLDREMQDQYFLIVQAYNSDLSVGTNEVPVIINILDINDVTP 1581 Query: 365 XFMP-GQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRG 421 F Y +L+E+ P GTPV+ + A D D D + Y + G +T + G Sbjct: 1582 LFQQQNYYRPDLSENSPSGTPVLQVFAQDQDLDLAGDVQYSLIGNPN----FLTINSDTG 1637 Query: 422 LITVAQPL-DFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASV 478 +I+V P+ D R + +TV ATD A V + + D P+F + Y A+V Sbjct: 1638 VISVNGPIADLSGSRNFTMTVRATDQASPFLRGVATVTVTVVDDTVTIPIFTLSRYPATV 1697 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 E+ T V VSAT + G A ITY++ S + + F I+ TG ITT Sbjct: 1698 IENVNADTPVTRVSATLN--GNPAGITYAIDPNASPAVL----EIFKIDENTGHITTEGA 1751 Query: 539 LDRETMSGYLLTVTA--RDGGVPSLSDTTDVEISVVDVNDNEPVF-KQQLYTANIMEDAL 595 +DRE Y TV A D P +T V ++++D NDN P F ++ E+ Sbjct: 1752 IDREVEDFYAFTVFAYHEDSVAPG---STSVWVNILDENDNPPEFITVPPSPVSVRENTG 1808 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKALDRESVATHD 654 V ATD D G+N ++ + + + F G I LDRE + Sbjct: 1809 GNVPVGLFRATDPDAGINAQMTFSISGAGSNFFNVFQTANGGGTIVVTSPLDRERQDFYQ 1868 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 L A DGG P SS+ ++I + D+ND+ P++ + I+EN+ I + +D Sbjct: 1869 LTVTATDGGNPSLSSSFPLNITVTDVNDNYPIWTRNVYEGSINENNFTSNPIITVMVNDL 1928 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY-ESPRKKYELVIRAASPP 773 D + YSI GD F + + + + + +++D + E+ + EL+ + SPP Sbjct: 1929 DLPSSNNFEYSIIAGDPMGMFEINS---NGEITVSSLLDREQQETYQLTIELIDQTNSPP 1985 Query: 774 LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYR 830 I V D NDN P+ + I + + P + A D D + + Y Sbjct: 1986 ARTTTLAIITVGDENDNTPIFAETVIRVDVTEGPSSQNIPVYMLTANDIDLGLNRDIIYA 2045 Query: 831 ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 I S + +N TG ++ + L+ T+ V+ TD Sbjct: 2046 IGSQQPQSHFQINPETGMISTTTALDWETISEYTLIVTATD 2086 Score = 255 bits (624), Expect = 1e-65 Identities = 230/796 (28%), Positives = 359/796 (45%), Gaps = 59/796 (7%) Query: 117 VKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKA 176 + T + ++ + + +N+I+ ND+ P F YT+++ ++IS + ++A Sbjct: 2361 IDQTIDSMGATEEKTGQTLVGINVININDHTPIFEGIPYTITLSKNISAGSLAYV--VRA 2418 Query: 177 TDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD--GGS 234 TD D G +RY I GNT F ID +G V + +YRLV+ A+D G Sbjct: 2419 TDDDAGIFGEVRYQITDGNTDNIFRIDQTTGQTGEVFVQGLLETGTYRLVVEARDTPGDI 2478 Query: 235 P-SRSNTTQLLINIRDVNDNAPRF-YTSLFQESVSENVPIGYSIVRVQAYDA-DEGVNAE 291 P SR+++T L I + D+ D AP F +SLF +V EN P+G I + A + + Sbjct: 2479 PSSRASSTTLTIVVTDIGDLAPTFPGSSLFTGNVFENAPVGQPITMIPPIRAINSDATGQ 2538 Query: 292 LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 L YT+T D I+ S + +G LDRET+ Y+ V TD +A T Sbjct: 2539 LVYTITGPD-----SQTFMINQLSAGIQVNGPLDRETKDFYEFGVIVTD--SMGLTAMGT 2591 Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGR 411 F Y + E+ P G V ++A D D DN + TGG + Sbjct: 2592 VHINVLDVNDFAPAFNDSVYNFTIPENSPGGYYVGGVSAYDLDGDNVNFFIQTGG--EDK 2649 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATD--SGGRSDTAMVQINITDANNYAPVF 469 F I +G +T LD +++ Y LTV +D + S TA V I + D N+ P F Sbjct: 2650 FDIGGTSGTITVTPGAVLDREEKPFYTLTVMVSDLRNPPLSGTATVYIYLIDINDSPPKF 2709 Query: 470 ENA--PYTASVFEDAPIGTTVLVVSATDSDV--GINAQI-TYSLSSEISNEAVAHHDQQ- 523 + + S+ ED P T V V+ATD D+ IN QI + S+ E + + D + Sbjct: 2710 DASFLDQIISIPEDTPGNTIVTTVTATDDDLNSNINYQIVSVSVYDEDDVDITSFFDYRT 2769 Query: 524 -FVINPQTGAITTNKLLDRETMSGYLLTVTARDGG-----VPSLSDTTDVEISVVDVNDN 577 F +NP G IT +DRE ++ +++ARD + + V I + D+NDN Sbjct: 2770 VFSLNPTNGNITLTSPVDREVTEKFVFSISARDLNSQNPIFGTSQENAQVTILITDINDN 2829 Query: 578 EPVFKQQLYT---ANIMEDALVGTSV-SQVGATDADVGLNGRIHYELDPKDREEGSFVID 633 P F+ T + E G+ + + A D D+GLNG + Y + ++ ID Sbjct: 2830 HPAFQPPGTTFILRQLPESFGAGSPIPGNLLALDPDLGLNGEVMYII--QNPSGVPVTID 2887 Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693 +G + +DRE +L +A+D GTP ++++ V+++I D ND+ PVF + T Sbjct: 2888 QNTGQLTLLVTVDREQQPWVNLTVLAVDKGTPSLNTSIPVYLEIIDNNDNNPVFGAQSHT 2947 Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753 I E+ PIG + + A D D G + V YS+ GGD F++ D + + Sbjct: 2948 TTIIESEPIGAFVFNVNATDADSGGSGRVTYSLIGGD--GKFTI----NQDSGVITLLQQ 3001 Query: 754 LDYESPRKKYELVIRAASPPLWNDVR-----VEILVTDVNDNAPVMKDFQIIFNNYKDCF 808 +D E+ + V +P D R V + V D N+ PV+ Q IF + Sbjct: 3002 VDKETQSQHMLTVFARDNPGDSEDSRTGSTTVIVNVLDANEFPPVVT--QPIFTIDEGGI 3059 Query: 809 PVGPFGRVPAYDADVTD----KLQYRILSGN---NANLILLNETTGSMTLSPQL---NTN 858 G + AYD D D L Y ++S L ++N TG + + L N Sbjct: 3060 GGEVVGVIEAYDPDDPDDPNQSLYYVVVSSQPEVGGTLFIINNATGEIITTGPLDRDNNL 3119 Query: 859 VPKLATMEVSVTDGVN 874 P ++V V D N Sbjct: 3120 HPARVDLDVIVYDDGN 3135 Score = 247 bits (604), Expect = 4e-63 Identities = 254/897 (28%), Positives = 389/897 (43%), Gaps = 98/897 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 INVLD ND +P F Y ++ E + G V + A D D G N V + I+ Sbjct: 2594 INVLDVNDFAPAFNDSVYNFTIPENSPGGYYVGGVSAYDLD-GDN--VNFFIQ------- 2643 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR--ASLDREKVARYTVLVKATDQASPVSD 128 +D F I G SG + A LDRE+ YT+ V +D +P Sbjct: 2644 -------------TGGEDKFDIGGTSGTITVTPGAVLDREEKPFYTLTVMVSDLRNP--- 2687 Query: 129 RLSSTATIHVNIIDDNDNYPQF--SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 LS TAT+++ +ID ND+ P+F S +S+ ED N ++ + ATD D+ NS Sbjct: 2688 PLSGTATVYIYLIDINDSPPKFDASFLDQIISIPED--TPGNTIVTTVTATDDDL--NSN 2743 Query: 187 IRYAIIGGNT--------------QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232 I Y I+ + + FS++ +G+++L +D E + I A+D Sbjct: 2744 INYQIVSVSVYDEDDVDITSFFDYRTVFSLNPTNGNITLTSPVDREVTEKFVFSISARDL 2803 Query: 233 GSP-----SRSNTTQLLINIRDVNDNAPRFY---TSLFQESVSENVPIGYSIV-RVQAYD 283 S + Q+ I I D+NDN P F T+ + E+ G I + A D Sbjct: 2804 NSQNPIFGTSQENAQVTILITDINDNHPAFQPPGTTFILRQLPESFGAGSPIPGNLLALD 2863 Query: 284 ADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD 343 D G+N E+ Y + + +P+TID +G + +DRE Q L V A D G Sbjct: 2864 PDLGLNGEVMYIIQNPS-----GVPVTIDQNTGQLTLLVTVDREQQPWVNLTVLAVDKGT 2918 Query: 344 PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHY 401 P + + F + + E EP G V + ATDAD R+ Y Sbjct: 2919 PSLNTSIPVYLEIIDNNDNNPVFGAQSHTTTIIESEPIGAFVFNVNATDADSGGSGRVTY 2978 Query: 402 EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG-----RSDTAMVQ 456 + GG+ G+F+I + G+IT+ Q +D + + +++LTV A D+ G R+ + V Sbjct: 2979 SLIGGD--GKFTINQDS--GVITLLQQVDKETQSQHMLTVFARDNPGDSEDSRTGSTTVI 3034 Query: 457 INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA 516 +N+ DAN + PV +T + E G V V+ A D D + SL + + Sbjct: 3035 VNVLDANEFPPVVTQPIFT--IDEGGIGGEVVGVIEAYDPDDPDDP--NQSLYYVVVSSQ 3090 Query: 517 VAHHDQQFVINPQTGAITTNKLLDRET---MSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 F+IN TG I T LDR+ + L V D G P+L T I + D Sbjct: 3091 PEVGGTLFIINNATGEIITTGPLDRDNNLHPARVDLDVIVYDDGNPNLGTPTTAIIYIND 3150 Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633 +NDN+P F LY ++E ++ V A D D N + YE+ + ++D Sbjct: 3151 LNDNQPTFDLPLYDVTVVEGQYSDPIITVV-ANDPD--QNSNLRYEILGGNLNNTFVLVD 3207 Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693 G+I K LD E+ ++L V D T V + + D ND P F D + Sbjct: 3208 --GGLIPV-KPLDFETFTNYNLTVVVTDDS--GNRDTTYVAVTVTDANDHNPTFVPDQYS 3262 Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAV-VHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752 ++EN P GT +G + D D P + Y+I G+ +F++ + G + T Sbjct: 3263 LTVTENEPPGTQVGAVITIDGDTLPEYTDIIYTILTGNGLGNFTINSTTGI----ITTAT 3318 Query: 753 DLDYESPRKKYELVIRAASP--PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV 810 LD E +Y L I A +P V I+V DVNDN P ++ I + V Sbjct: 3319 ILDREK-TSEYVLTIGAENPVGGTTGTATVSIIVRDVNDNTPTFEENPYISTVTTNTLLV 3377 Query: 811 GPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867 P D + Y I+SGN N ++ TG +TL L++ + + T+ V Sbjct: 3378 DVHANDP--DEGGNGIVIYEIVSGNEDNRFQIDNRTGVITLVNPLDSQLIRNYTLVV 3432 Score = 239 bits (586), Expect = 6e-61 Identities = 201/722 (27%), Positives = 325/722 (45%), Gaps = 45/722 (6%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72 V D ND++P F YE S+ E G+ +LT++A D D+G NA V Y I ++ + N Sbjct: 1468 VTDVNDNAPTFRDISYEESIFENHPLGSNILTVQADDPDLGVNAVVLYRI--ISGNNNN- 1524 Query: 73 EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132 +F +DG+ L LDRE +Y ++V+A + V ++ Sbjct: 1525 ----------------LFNVDGQGNINLGSTPLDREMQDQYFLIVQAYNSDLSVG---TN 1565 Query: 133 TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192 + +NI+D ND P F ++ Y + S + PV+ ++ A D D+ ++Y++I Sbjct: 1566 EVPVIINILDINDVTPLFQQQNYYRPDLSENSPSGTPVL-QVFAQDQDLDLAGDVQYSLI 1624 Query: 193 GGNTQMQFSIDSLSGDVSLVKTL-DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251 G + +I+S +G +S+ + D R++ + +RA D SP + + + D Sbjct: 1625 GNPNFL--TINSDTGVISVNGPIADLSGSRNFTMTVRATDQASPFLRGVATVTVTVVDDT 1682 Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311 P F S + +V ENV + RV A G A +TY + +++ I Sbjct: 1683 VTIPIFTLSRYPATVIENVNADTPVTRVSA--TLNGNPAGITYAIDPNASPAVLEI-FKI 1739 Query: 312 DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371 D +G + T G +DRE + Y V A +T+ Sbjct: 1740 DENTGHITTEGAIDREVEDFYAFTVFAYHEDSVAPGSTSVWVNILDENDNPPEFITVPPS 1799 Query: 372 EVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 V + E+ PV ATD D + ++ + I+G + + NG G I V PL Sbjct: 1800 PVSVRENTGGNVPVGLFRATDPDAGINAQMTFSISGAGSNFFNVFQTANGGGTIVVTSPL 1859 Query: 430 DFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTT 487 D +++ Y LTV+ATD G S ++ +NIT D N+ P++ Y S+ E+ Sbjct: 1860 DRERQDFYQLTVTATDGGNPSLSSSFPLNITVTDVNDNYPIWTRNVYEGSINENNFTSNP 1919 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 ++ V D D+ + YS+ I+ + + F IN G IT + LLDRE Y Sbjct: 1920 IITVMVNDLDLPSSNNFEYSI---IAGDPMG----MFEIN-SNGEITVSSLLDREQQETY 1971 Query: 548 LLTVTARDG-GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED-ALVGTSVSQVGA 605 LT+ D P TT I+V D NDN P+F + + ++ E + V + A Sbjct: 1972 QLTIELIDQTNSPPARTTTLAIITVGDENDNTPIFAETVIRVDVTEGPSSQNIPVYMLTA 2031 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG-T 664 D D+GLN I Y + + + + F I+P +G+I T ALD E+++ + L A D T Sbjct: 2032 NDIDLGLNRDIIYAIGSQ-QPQSHFQINPETGMISTTTALDWETISEYTLIVTATDQSPT 2090 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 P++ T V + + DIND P+F D Y + I +A D D+G V Y Sbjct: 2091 EPRTGTATVIVSVNDINDGAPMFVRDVYGPYSVVEEVSNSYIDSFQATDTDQGLAGTVTY 2150 Query: 725 SI 726 S+ Sbjct: 2151 SV 2152 Score = 239 bits (584), Expect = 1e-60 Identities = 224/807 (27%), Positives = 356/807 (44%), Gaps = 68/807 (8%) Query: 11 INVLDCNDHSPVFEMQQYEA--SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68 I ++D ND P F+ + S+ E T V T+ ATD D+ N+ + Y ++V+ Sbjct: 2697 IYLIDINDSPPKFDASFLDQIISIPEDTPGNTIVTTVTATDDDL--NSNINY--QIVSVS 2752 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS--PV 126 + +D + VF ++ +G + + +DRE ++ + A D S P+ Sbjct: 2753 VYDEDDVDITSFFDY---RTVFSLNPTNGNITLTSPVDREVTEKFVFSISARDLNSQNPI 2809 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEK--TYTVSVDEDISVTDNPVIAKIKATDADVGAN 184 A + + I D NDN+P F T+ + + +P+ + A D D+G N Sbjct: 2810 FGTSQENAQVTILITDINDNHPAFQPPGTTFILRQLPESFGAGSPIPGNLLALDPDLGLN 2869 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 + Y II + + +ID +G ++L+ T+D EQ L + A D G+PS + + + Sbjct: 2870 GEVMY-IIQNPSGVPVTIDQNTGQLTLLVTVDREQQPWVNLTVLAVDKGTPSLNTSIPVY 2928 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + I D NDN P F ++ E+ PIG + V A DAD G + +TY++ D G Sbjct: 2929 LEIIDNNDNNPVFGAQSHTTTIIESEPIGAFVFNVNATDADSGGSGRVTYSLIGGD--GK 2986 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG-GDPPRSATATXXXXXXXXXXXX 363 TI+ SG + Q+D+ETQ+++ L V A D GD S T + Sbjct: 2987 ----FTINQDSGVITLLQQVDKETQSQHMLTVFARDNPGDSEDSRTGSTTVIVNVLDANE 3042 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADE----DNRLHYEITGGNTR-GRFSITSQN 418 + Q + E G V + A D D+ + L+Y + G N Sbjct: 3043 FPPVVTQPIFTIDEGGIGGEVVGVIEAYDPDDPDDPNQSLYYVVVSSQPEVGGTLFIINN 3102 Query: 419 GRGLITVAQPLDFKQE---RRYVLTVSATDSG----GRSDTAMVQINITDANNYAPVFEN 471 G I PLD R L V D G G TA++ IN D N+ P F+ Sbjct: 3103 ATGEIITTGPLDRDNNLHPARVDLDVIVYDDGNPNLGTPTTAIIYIN--DLNDNQPTFDL 3160 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS-LSSEISNEAVAHHDQQFVINPQT 530 Y +V E ++ V A D D N+ + Y L ++N FV+ Sbjct: 3161 PLYDVTVVE-GQYSDPIITVVANDPDQ--NSNLRYEILGGNLNN--------TFVL--VD 3207 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590 G + K LD ET + Y LTV D DTT V ++V D ND+ P F Y+ + Sbjct: 3208 GGLIPVKPLDFETFTNYNLTVVVTDDS--GNRDTTYVAVTVTDANDHNPTFVPDQYSLTV 3265 Query: 591 MEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES 649 E+ GT V V D D + I Y + G+F I+ +G+I T LDRE Sbjct: 3266 TENEPPGTQVGAVITIDGDTLPEYTDIIYTI-LTGNGLGNFTINSTTGIITTATILDREK 3324 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 + + L + + + T V I + D+ND+ P FE + ++ N T + ++ Sbjct: 3325 TSEYVL-TIGAENPVGGTTGTATVSIIVRDVNDNTPTFEENPYISTVTTN----TLLVDV 3379 Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVI- 767 A+DPDEG N +V Y I G++ N F ++ R G ++T+V+ LD + R Y LV+ Sbjct: 3380 HANDPDEGGNGIVIYEIVSGNEDNRFQIDNRTG-----VITLVNPLDSQLIR-NYTLVVI 3433 Query: 768 --RAASPPLWNDVRVEILVTDVNDNAP 792 +P L ++ V++ + + NAP Sbjct: 3434 GHDLGNPRLQSNTTVDLRINYLGLNAP 3460 Score = 231 bits (565), Expect = 2e-58 Identities = 226/756 (29%), Positives = 339/756 (44%), Gaps = 93/756 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND++P FE Y ++V ++ T ++ + A D D G N V Y E+V+ + Sbjct: 3349 IIVRDVNDNTPTFEENPYISTV----TTNTLLVDVHANDPDEGGNGIVIY--EIVSGN-- 3400 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 ED + F+ID R+G + LD + + YT++V D +P RL Sbjct: 3401 --ED-------------NRFQIDNRTGVITLVNPLDSQLIRNYTLVVIGHDLGNP---RL 3442 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDN----PVIAKIKATDADVGANSA 186 S T+ + I N P + S + +T+N +I A D DVGAN Sbjct: 3443 QSNTTVDLRINYLGLNAPPSFVRPNQGST---VFITENNPLGQLIINAFAVDDDVGANGV 3499 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 + Y+I+ + D +G + VK LD+E +Y L + D +TT + + Sbjct: 3500 VDYSILP-------NFD-YNGGLIPVKPLDFETFTNYNLTVVVTDDSG--NRDTTYVAVT 3549 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN-AELTYTMTDKDYTGNV 305 + D ND+ P F + +V+EN P G + V D D ++ YT+ + GN Sbjct: 3550 VTDANDHNPTFVPDQYSLTVTENEPPGTQVGVVITIDGDTLPEYTDIIYTILTGNGLGN- 3608 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD--GGDPPRSATATXXXXXXXXXXXX 363 TI+ +G + T+ LDRE ++Y L + A + GG + TAT Sbjct: 3609 ---FTINSTTGIITTATILDREKTSEYVLTIGAENPVGGT---TGTATVSIIVRDVNDNT 3662 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRG 421 F Y + + T +V + A D DE + YEI GN RF+I N G Sbjct: 3663 PTFEENPYTSTVTTN----TLLVDVHANDPDEGGNGIVIYEIVSGNEDNRFTI--DNRTG 3716 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGG---RSDTAM-VQINITDANNYAPVFENAPYTAS 477 +IT+ PL+ + R Y L V D G +S+T + ++IN N P F ++ Sbjct: 3717 VITLVNPLESQLIRNYTLVVIGHDLGNPQLQSNTTVDLRINYLGLNA-PPSFVRPNQGST 3775 Query: 478 VF--EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 VF E+ P+G ++ A D DVG N + YS+ F I+P TG IT Sbjct: 3776 VFITENNPLGLLIINAFAVDDDVGANGVVDYSILPNFDYS-------DFTIDPVTGDITI 3828 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ-------LYTA 588 DRE Y LTV A D G P+LS ++ I V+D NDN P F + + Sbjct: 3829 LVSADREIKDSYTLTVVATDRGDPNLSTSSTFVIRVLDENDNNPAFPRPDGMNNPIVLNL 3888 Query: 589 NIMEDALVGTSVSQV-GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647 N+ E+A + V V GA D D+G NG+I Y + G FVI+ +GV+ N LDR Sbjct: 3889 NVFENANISDLVGTVDGAIDLDLGANGQIFYHI-VDSTVGGIFVINSTTGVVTVNGTLDR 3947 Query: 648 ESVATHDLKAVAID----GGTPPQS-----STVIVHIKIEDINDSPPVFESDCLTFYISE 698 E + H + +A + GT P + S V I + DIND+ P F S ++ I Sbjct: 3948 EDIGVHTIYILATNDATYNGTGPYNVLDNISLKEVKITLLDINDNAPRFTSTVISACIPF 4007 Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734 + +G T+ + D D G N + YS+ NS Sbjct: 4008 DISLGMTVVSVAVVDLDGGTNLGIAYSLNSIQFINS 4043 Score = 212 bits (517), Expect = 1e-52 Identities = 231/840 (27%), Positives = 362/840 (43%), Gaps = 100/840 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASS-GTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 I V D ND++P+F V EG SS V L A D D+G N ++ Y I + Sbjct: 1994 ITVGDENDNTPIFAETVIRVDVTEGPSSQNIPVYMLTANDIDLGLNRDIIYAI-----GS 2048 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 P Q F+I+ +G + T +LD E ++ YT++V ATDQ SP R Sbjct: 2049 QQP--------------QSHFQINPETGMISTTTALDWETISEYTLIVTATDQ-SPTEPR 2093 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTY-TVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 + TAT+ V++ D ND P F Y SV E++S N I +ATD D G + Sbjct: 2094 -TGTATVIVSVNDINDGAPMFVRDVYGPYSVVEEVS---NSYIDSFQATDTDQGLAGTVT 2149 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y++I + DV ++ E SY +A D T +I Sbjct: 2150 YSVIVSVNDINDGAPMFVRDVYGPYSVVEEVSNSYIDSFQATDTDQGLAGMVTYSVIGQ- 2208 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 Y+ LF V +I +A D + +T TD Sbjct: 2209 ---------YSDLFFIQPQTGV---LTIRPDRALDYETITEFNITVVATDMGVPA----- 2251 Query: 309 ITIDPRSG--WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 ++ P++G + LD ET ++ + V ATD G+P S++ F Sbjct: 2252 LSSSPQTGVLTIRPDRALDYETITEFNITVVATDMGNPALSSSTLVGINVININDHTPIF 2311 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLIT 424 Y + L+++ G+ + ATD D + Y+IT GNT F I Sbjct: 2312 EGIPYTITLSKNISAGSLAYVVRATDDDAGIFGEVRYQITDGNTDNIFRID--------- 2362 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 Q +D ++ AT+ ++ +V IN+ + N++ P+FE PYT ++ ++ Sbjct: 2363 --QTID---------SMGATEE--KTGQTLVGINVININDHTPIFEGIPYTITLSKNISA 2409 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 G+ VV ATD D GI ++ Y + ++ + + + DQ QTG + LL+ T Sbjct: 2410 GSLAYVVRATDDDAGIFGEVRYQI-TDGNTDNIFRIDQ---TTGQTGEVFVQGLLETGT- 2464 Query: 545 SGYLLTVTARD--GGVP-SLSDTTDVEISVVDVNDNEPVFK-QQLYTANIMEDALVGTSV 600 Y L V ARD G +P S + +T + I V D+ D P F L+T N+ E+A VG + Sbjct: 2465 --YRLVVEARDTPGDIPSSRASSTTLTIVVTDIGDLAPTFPGSSLFTGNVFENAPVGQPI 2522 Query: 601 SQVGATDA-DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 + + A + G++ Y + D + +F+I+ S I+ N LDRE+ ++ + Sbjct: 2523 TMIPPIRAINSDATGQLVYTITGPDSQ--TFMINQLSAGIQVNGPLDRETKDFYEFGVIV 2580 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 D T VHI + D+ND P F F I ENSP G +G + A+D D G N Sbjct: 2581 TDSMGLTAMGT--VHINVLDVNDFAPAFNDSVYNFTIPENSPGGYYVGGVSAYDLD-GDN 2637 Query: 720 AVVHYSIK-GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDV 778 V++ I+ GG+D F + G+ ++D + + +V +PPL Sbjct: 2638 --VNFFIQTGGED--KFDIGGTSGTITVTPGAVLDREEKPFYTLTVMVSDLRNPPLSGTA 2693 Query: 779 RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR-----VPAYDADVTDKLQYRILS 833 V I + D+ND+ P F F + P G V A D D+ + Y+I+S Sbjct: 2694 TVYIYLIDINDSPP---KFDASFLDQIISIPEDTPGNTIVTTVTATDDDLNSNINYQIVS 2750 Score = 200 bits (488), Expect = 4e-49 Identities = 156/516 (30%), Positives = 249/516 (48%), Gaps = 24/516 (4%) Query: 373 VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432 V++ E + P V TL ATD D D + Y++ R F+I G+ + LD++ Sbjct: 523 VKVTEGQSPSILVFTLNATDPDGDP-ITYDLFDDEARSIFTINQFTGQ--LYALPGLDYE 579 Query: 433 Q-ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491 + ++TVS TD + + ITD N+ AP F N P VFE+A G+ + V Sbjct: 580 TLGNQVIITVSVTDGINDPVPQTIYVRITDVNDIAPTFTNLPNITYVFENATFGSELYQV 639 Query: 492 SATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTV 551 TD D +TYS+S + + + F I G I L+ E + Y +TV Sbjct: 640 ITTDEDTFYGGFVTYSISLVTPSTPGSAPNNYFSIGETDGIIQLATSLNYEEIQQYFVTV 699 Query: 552 TARDGGV--PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 ARD G SLS T + +SV+++ D PVF Y I E VG++V + ATD D Sbjct: 700 VARDYGTGDTSLSSTATLTVSVLNIQDTNPVFINTPYDVTIPETLPVGSTVQTITATDPD 759 Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES---VATHDLKAVAIDGGTPP 666 I Y L D +G FVID +G+I N +DR++ AT+ L A++ + Sbjct: 760 SNDGNIITYNLVVSD-SQGYFVIDQTTGIITVNSQMDRDNPVLPATYPLIVSAVETSSGG 818 Query: 667 QS-STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG-EIRAHDPDEGPNAVVHY 724 S + V ++ + ND PP+F+ + + I E++ + + + I +D D ++ V Sbjct: 819 VSFAQVSFNVTVSPANDEPPMFDQNSYSASIPESASVNSQLPITITVNDGDLITDSTVTV 878 Query: 725 SIKGGDDSNSFSLETRQ--GSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEI 782 S++ G +S F + Q GS +++ LD+E+ ++Y L ++A + + + Sbjct: 879 SLQNG-NSVPFRVSPTQVVGSGTVDILITQPLDFEN-NQQYTLQLQAVDGDGQDIAPLMV 936 Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCF----PVGPF-GRVPAYDADVTDK--LQYRILSGN 835 VTDVNDN PV + + I N Y+ G F +V DAD + Y I+SGN Sbjct: 937 TVTDVNDNNPVFIN-RPIDNIYRGSINENDQTGTFIVQVSTTDADSGSNAAVTYSIISGN 995 Query: 836 NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 N+ +N T+G++T + L N P+ T+ V T+ Sbjct: 996 INNVFTINPTSGAITNTQILGPNTPQTYTLSVRATN 1031 Score = 190 bits (462), Expect = 6e-46 Identities = 170/576 (29%), Positives = 258/576 (44%), Gaps = 68/576 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTADT 69 + V D NDH+P F QY +V E GT V + D D + + ++ YTI +T + Sbjct: 3548 VTVTDANDHNPTFVPDQYSLTVTENEPPGTQVGVVITIDGDTLPEYTDIIYTI--LTGNG 3605 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L F I+ +G + T LDREK + Y + + A + PV Sbjct: 3606 LGN-----------------FTINSTTGIITTATILDREKTSEYVLTIGAEN---PVGGT 3645 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + TAT+ + + D NDN P F E YT +V T N ++ + A D D G N + Y Sbjct: 3646 -TGTATVSIIVRDVNDNTPTFEENPYTSTV------TTNTLLVDVHANDPDEGGNGIVIY 3698 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I+ GN +F+ID+ +G ++LV L+ + +R+Y LV+ D G+P + T + + I Sbjct: 3699 EIVSGNEDNRFTIDNRTGVITLVNPLESQLIRNYTLVVIGHDLGNPQLQSNTTVDLRINY 3758 Query: 250 VNDNAPRFYTSLFQES---VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK-DYTGNV 305 + NAP + Q S ++EN P+G I+ A D D G N + Y++ DY+ Sbjct: 3759 LGLNAPPSFVRPNQGSTVFITENNPLGLLIINAFAVDDDVGANGVVDYSILPNFDYSD-- 3816 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 TIDP +G + DRE + Y L V ATD GDP S ++T Sbjct: 3817 ---FTIDPVTGDITILVSADREIKDSYTLTVVATDRGDPNLSTSSTFVIRVLDENDNNPA 3873 Query: 366 FM-------PGQYEVELAEDEPPGTPVVTLT-ATDAD--EDNRLHYEITGGNTRGRFSIT 415 F P + + E+ V T+ A D D + ++ Y I G F I Sbjct: 3874 FPRPDGMNNPIVLNLNVFENANISDLVGTVDGAIDLDLGANGQIFYHIVDSTVGGIFVIN 3933 Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM-----------VQINITDANN 464 S G ++TV LD + + + + AT+ + T V+I + D N+ Sbjct: 3934 STTG--VVTVNGTLDREDIGVHTIYILATNDATYNGTGPYNVLDNISLKEVKITLLDIND 3991 Query: 465 YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS----EISNEAVAHH 520 AP F + +A + D +G TV+ V+ D D G N I YSL+S E +A Sbjct: 3992 NAPRFTSTVISACIPFDISLGMTVVSVAVVDLDGGTNLGIAYSLNSIQFINSEGERLAAI 4051 Query: 521 DQQFVINPQTGAITTNKLLDRETMSGYL-LTVTARD 555 + F IN +TG I TN+ + GY + V A D Sbjct: 4052 N-AFTINSETGQIVTNQRFGEAYLQGYFDIVVQATD 4086 Score = 167 bits (405), Expect = 5e-39 Identities = 146/515 (28%), Positives = 234/515 (45%), Gaps = 43/515 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V+D P+F + +Y A+V E ++ T V + AT G A + Y I+ Sbjct: 1676 VTVVDDTVTIPIFTLSRYPATVIENVNADTPVTRVSATLN--GNPAGITYAID----PNA 1729 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +P V ++F+ID +G + T ++DRE Y V A + S Sbjct: 1730 SP------------AVLEIFKIDENTGHITTEGAIDREVEDFYAFTVFAYHEDSVA---- 1773 Query: 131 SSTATIHVNIIDDNDNYPQF-SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + ++ VNI+D+NDN P+F + VSV E+ N + +ATD D G N+ + + Sbjct: 1774 PGSTSVWVNILDENDNPPEFITVPPSPVSVRENTG--GNVPVGLFRATDPDAGINAQMTF 1831 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 +I G + + +G ++V T LD E+ Y+L + A DGG+PS S++ L I + Sbjct: 1832 SISGAGSNFFNVFQTANGGGTIVVTSPLDRERQDFYQLTVTATDGGNPSLSSSFPLNITV 1891 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 DVNDN P + ++++ S++EN I+ V D D + Y++ D G ++ Sbjct: 1892 TDVNDNYPIWTRNVYEGSINENNFTSNPIITVMVNDLDLPSSNNFEYSIIAGDPMGMFEI 1951 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATD-GGDPPRSATATXXXXXXXXXXXXXXF 366 +G + S LDRE Q YQL + D PP T F Sbjct: 1952 -----NSNGEITVSSLLDREQQETYQLTIELIDQTNSPPARTTTLAIITVGDENDNTPIF 2006 Query: 367 MPGQYEVELAE-DEPPGTPVVTLTATDADED-NR-LHYEITGGNTRGRFSITSQNGRGLI 423 V++ E PV LTA D D NR + Y I + F I + G+I Sbjct: 2007 AETVIRVDVTEGPSSQNIPVYMLTANDIDLGLNRDIIYAIGSQQPQSHFQINPET--GMI 2064 Query: 424 TVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPY-TASVF 479 + LD++ Y L V+ATD R+ TA V +++ D N+ AP+F Y SV Sbjct: 2065 STTTALDWETISEYTLIVTATDQSPTEPRTGTATVIVSVNDINDGAPMFVRDVYGPYSVV 2124 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 E+ + + ATD+D G+ +TYS+ +++ Sbjct: 2125 EEVS-NSYIDSFQATDTDQGLAGTVTYSVIVSVND 2158 Score = 92.7 bits (220), Expect = 1e-16 Identities = 137/521 (26%), Positives = 225/521 (43%), Gaps = 42/521 (8%) Query: 378 DEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435 +E + + + ATD D+ + Y + G + F I Q G I + LD++ Sbjct: 2178 EEVSNSYIDSFQATDTDQGLAGMVTYSVIGQYS-DLFFIQPQTGVLTIRPDRALDYETIT 2236 Query: 436 RYVLTVSATDSG-----GRSDTAMVQINITDANNYAPVFE-NAPYTASVFEDAPIGTTVL 489 + +TV ATD G T ++ I A +Y + E N A+ + + ++ L Sbjct: 2237 EFNITVVATDMGVPALSSSPQTGVLTIRPDRALDYETITEFNITVVATDMGNPALSSSTL 2296 Query: 490 ----VVSATD-SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 V++ D + + T +LS IS ++A+ + + ++ D T Sbjct: 2297 VGINVININDHTPIFEGIPYTITLSKNISAGSLAYVVRATDDDAGIFGEVRYQITDGNTD 2356 Query: 545 SGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 + + + T G + T V I+V+++ND+ P+F+ YT + ++ G+ V Sbjct: 2357 NIFRIDQTIDSMGATEEKTGQTLVGINVININDHTPIFEGIPYTITLSKNISAGSLAYVV 2416 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 ATD D G+ G + Y++ + F ID +G +T + + + T + V Sbjct: 2417 RATDDDAGIFGEVRYQI-TDGNTDNIFRIDQTTG--QTGEVFVQGLLETGTYRLVVEARD 2473 Query: 664 TP---PQS--STVIVHIKIEDINDSPPVFE-SDCLTFYISENSPIG---TTIGEIRAHDP 714 TP P S S+ + I + DI D P F S T + EN+P+G T I IRA + Sbjct: 2474 TPGDIPSSRASSTTLTIVVTDIGDLAPTFPGSSLFTGNVFENAPVGQPITMIPPIRAINS 2533 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL-VIRAASPP 773 D V Y+I G DS +F + A + LD E+ + YE VI S Sbjct: 2534 DATGQLV--YTIT-GPDSQTFMINQL----SAGIQVNGPLDRET-KDFYEFGVIVTDSMG 2585 Query: 774 LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDKLQYRIL 832 L V I V DVND AP D F + P G + G V AYD D D + + I Sbjct: 2586 LTAMGTVHINVLDVNDFAPAFNDSVYNF-TIPENSPGGYYVGGVSAYDLD-GDNVNFFIQ 2643 Query: 833 SGNNANLILLNETTGSMTLSP--QLNTNVPKLATMEVSVTD 871 +G + + T+G++T++P L+ T+ V V+D Sbjct: 2644 TGGE-DKFDIGGTSGTITVTPGAVLDREEKPFYTLTVMVSD 2683 Score = 38.3 bits (85), Expect = 3.0 Identities = 33/136 (24%), Positives = 62/136 (45%), Gaps = 14/136 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I +LD ND++P F A + S G TV+++ D D G N + Y++ + Sbjct: 3983 KITLLDINDNAPRFTSTVISACIPFDISLGMTVVSVAVVDLDGGTNLGIAYSLNSI--QF 4040 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARY-TVLVKATDQASPVSD 128 +N E + F I+ +G ++T + Y ++V+ATD V+ Sbjct: 4041 INSEGERLAAI-------NAFTINSETGQIVTNQRFGEAYLQGYFDIVVQATD----VNT 4089 Query: 129 RLSSTATIHVNIIDDN 144 + A+I + I+++N Sbjct: 4090 GQFAVASIRLCILNNN 4105 >UniRef50_Q9NYQ8 Cluster: Protocadherin Fat 2 precursor; n=19; Amniota|Rep: Protocadherin Fat 2 precursor - Homo sapiens (Human) Length = 4349 Score = 339 bits (833), Expect = 7e-91 Identities = 230/720 (31%), Positives = 349/720 (48%), Gaps = 47/720 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 Q+++ D ND++P F ++Y SV E + G V TLK D DI + + T + D Sbjct: 2893 QVSITDENDNAPRFASEEYRGSVVENSEPGELVATLKTLDADISEQNR-QVTCYITEGDP 2951 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L V D +RI R +LDRE A+Y + V A+D + Sbjct: 2952 LGQ--------FGISQVGDEWRISSRK-------TLDREHTAKYLLRVTASD------GK 2990 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 ++ T+ + ++D NDN PQ S+ YT V ED V I K+ ATD D N+ I Y Sbjct: 2991 FQASVTVEIFVLDVNDNSPQCSQLLYTGKVHED--VFPGHFILKVSATDLDTDTNAQITY 3048 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 ++ G +F +D +G+++ + LD E+ + LV +A DGG RS + +++ D Sbjct: 3049 SLHGPGAH-EFKLDPHTGELTTLTALDRERKDVFNLVAKATDGGG--RSCQADITLHVED 3105 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 VNDNAPRF+ S +V +N + + V A D D+G NA++ Y++ D + + Sbjct: 3106 VNDNAPRFFPSHCAVAVFDNTTVKTPVAVVFARDPDQGANAQVVYSLPD-----SAEGHF 3160 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSATATXXXXXXXXXXXXXXFMP 368 +ID +G + L QA +L V A+D G P P S T F+ Sbjct: 3161 SIDATTGVIRLEKPLQVRPQAPLELTVRASDLGTPIPLSTLGTVTVSVVGLEDYLPVFLN 3220 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 ++ V++ ED PPGT V+ L + Y + GN +GRF + ++ G++ V Sbjct: 3221 TEHSVQVPEDAPPGTEVLQLATLTRPGAEKTGYRVVSGNEQGRFRLDART--GILYVNAS 3278 Query: 429 LDFKQERRYVLTV--SATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LDF+ +Y L++ S S SD V +NITD N + P F PY+ V E+A +G Sbjct: 3279 LDFETSPKYFLSIECSRKSSSSLSDVTTVMVNITDVNEHRPQFPQDPYSTRVLENALVGD 3338 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 +L VSATD D +N+ ITYSL I + H F I+P+ G + K LDRE S Sbjct: 3339 VILTVSATDEDGPLNSDITYSL---IGGNQLGH----FTIHPKKGELQVAKALDREQASS 3391 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y L + A D G P L + TD+ I V DVNDN P F Q Y+ + E++ +G+ V Q+ + Sbjct: 3392 YSLKLRATDSGQPPLHEDTDIAIQVADVNDNPPRFFQLNYSTTVQENSPIGSKVLQLILS 3451 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D D NG + K +F + P G + T + L R + + L+ A D G PP Sbjct: 3452 DPDSPENGPPYSFRITKGNNGSAFRVTP-DGWLVTAEGLSRRAQEWYQLQIQASDSGIPP 3510 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 SS V + + + + P + + E+ G +G+I A D D P + YS+ Sbjct: 3511 LSSLTSVRVHVTEQSHYAPSALPLEIFITVGEDEFQGGMVGKIHATDRD--PQDTLTYSL 3568 Score = 312 bits (767), Expect = 7e-83 Identities = 260/881 (29%), Positives = 401/881 (45%), Gaps = 58/881 (6%) Query: 3 VPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 V FC +I + D ND+ P F+ +Y S++ S + V+ + A D D G+NA+V Y++ Sbjct: 2566 VAFCT-VKIILTDENDNPPQFKASEYTVSIQSNVSKDSPVIQVLAYDADEGQNADVTYSV 2624 Query: 63 ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122 NPED V+DV I+ +G + + SL + +KA D Sbjct: 2625 --------NPED----------LVKDVIEINPVTGVVKVKDSLVGLENQTLDFFIKAQDG 2666 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA-DV 181 P +S + + ++ + P+FSE YT S ED+ + I +KA A D Sbjct: 2667 GPP---HWNSLVPVRLQVVPKKVSLPKFSEPLYTFSAPEDL--PEGSEIGIVKAVAAQDP 2721 Query: 182 GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 S +R N FS+D +G + + K +D+E + Y++ + A + + Sbjct: 2722 VIYSLVRGTTPESNKDGVFSLDPDTGVIKVRKPMDHESTKLYQIDVMAHCLQNTDVVSLV 2781 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 + I + DVNDN P F ++ ++EN+P+G S+++V A D D G + +++Y ++ D Sbjct: 2782 SVNIQVGDVNDNRPVFEADPYKAVLTENMPVGTSVIQVTAIDKDTGRDGQVSYRLS-ADP 2840 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR-SATATXXXXXXXXX 360 NV ID SGW+ T +LD ET Y V A D G + S+ A Sbjct: 2841 GSNVHELFAIDSESGWITTLQELDCETCQTYHFHVVAYDHGQTIQLSSQALVQVSITDEN 2900 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNR-LHYEITGGNTRGRFSITSQ 417 F +Y + E+ PG V TL DAD E NR + IT G+ G+F I+ Sbjct: 2901 DNAPRFASEEYRGSVVENSEPGELVATLKTLDADISEQNRQVTCYITEGDPLGQFGISQV 2960 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTAS 477 I+ + LD + +Y+L V+A+D G + V+I + D N+ +P YT Sbjct: 2961 GDEWRISSRKTLDREHTAKYLLRVTASD-GKFQASVTVEIFVLDVNDNSPQCSQLLYTGK 3019 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 V ED G +L VSATD D NAQITYSL ++E F ++P TG +TT Sbjct: 3020 VHEDVFPGHFILKVSATDLDTDTNAQITYSLHGPGAHE--------FKLDPHTGELTTLT 3071 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LDRE + L A DGG S D+ + V DVNDN P F + ++ V Sbjct: 3072 ALDRERKDVFNLVAKATDGG--GRSCQADITLHVEDVNDNAPRFFPSHCAVAVFDNTTVK 3129 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 T V+ V A D D G N ++ Y L D EG F ID +GVIR K L A +L Sbjct: 3130 TPVAVVFARDPDQGANAQVVYSL--PDSAEGHFSIDATTGVIRLEKPLQVRPQAPLELTV 3187 Query: 658 VAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 A D GTP P S+ V + + + D PVF + + + E++P GT + ++ Sbjct: 3188 RASDLGTPIPLSTLGTVTVSVVGLEDYLPVFLNTEHSVQVPEDAPPGTEVLQLATL---T 3244 Query: 717 GPNA-VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI---RAASP 772 P A Y + G++ F L+ R G L LD+E+ KY L I R +S Sbjct: 3245 RPGAEKTGYRVVSGNEQGRFRLDARTGI----LYVNASLDFET-SPKYFLSIECSRKSSS 3299 Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYR 830 L + V + +TDVN++ P ++ V A D D + + Y Sbjct: 3300 SLSDVTTVMVNITDVNEHRPQFPQDPYSTRVLENALVGDVILTVSATDEDGPLNSDITYS 3359 Query: 831 ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 ++ GN ++ G + ++ L+ ++++ TD Sbjct: 3360 LIGGNQLGHFTIHPKKGELQVAKALDREQASSYSLKLRATD 3400 Score = 298 bits (731), Expect = 2e-78 Identities = 261/888 (29%), Positives = 400/888 (45%), Gaps = 75/888 (8%) Query: 11 INVLDCNDHSPVFEMQQYEA-SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ N ++P FE ++ V E T + L ATD D G N ++ Y I AD Sbjct: 702 LSTYQINHYTPQFEDHFPQSIDVLESVPINTPLARLAATDPDAGFNGKLVYVI----ADG 757 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N E F I+ +G L A LD E Y + V D +P + Sbjct: 758 -NEEGC--------------FDIELETGLLTVAAPLDYEATNFYILNVTVYDLGTP---Q 799 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 SS + VN+ D NDN P+F Y +++ ED V IA++ DAD N +RY Sbjct: 800 KSSWKLLTVNVKDWNDNAPRFPPGGYQLTISEDTEV--GTTIAELTTKDADSEDNGRVRY 857 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS--NTTQLLINI 247 ++ + FS+ L+G++ + LD E Y L + A+D S + T L+I + Sbjct: 858 TLLSPTEK--FSLHPLTGELVVTGHLDRESEPRYILKVEARDQPSKGHQLFSVTDLIITL 915 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY-TGNVD 306 DVNDN+P+ T + V E++P G + + A D D G E+ Y + D + T VD Sbjct: 916 EDVNDNSPQCITEHNRLKVPEDLPPGTVLTFLDASDPDLGPAGEVRYVLMDGAHGTFRVD 975 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX-- 364 L +G + +LD E +A Y L + A+DGG P T Sbjct: 976 L------MTGALILERELDFERRAGYNLSLWASDGGRPLARRTLCHVEVIVLDVNENLHP 1029 Query: 365 -XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRG 421 F ++ ++ E+ P GT V+ + A D D D L Y + G FSI G Sbjct: 1030 PHFASFVHQGQVQENSPSGTQVIVVAAQDDDSGLDGELQYFLRAGTGLAAFSINQDT--G 1087 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVF 479 +I PLD + Y LTV A D G S V I +TDAN+ P A + S+ Sbjct: 1088 MIQTLAPLDREFASYYWLTVLAVDRGSVPLSSVTEVYIEVTDANDNPPQMSQAVFYPSIQ 1147 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 EDAP+GT+VL + A D D ++T++++S ++ F+I+P TG ++T + L Sbjct: 1148 EDAPVGTSVLQLDAWDPDSSSKGKLTFNITS-------GNYMGFFMIHPVTGLLSTAQQL 1200 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME--DALVG 597 DRE ++L VT D G PSL T+ V + ++DVNDN P+F +L+ + E + Sbjct: 1201 DRENKDEHILEVTVLDNGEPSLKSTSRVVVGILDVNDNPPIFSHKLFNVRLPERLSPVSP 1260 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 V ++ A+D D GLNGR+ Y ++ D E +F ID +GV+ +N +KA Sbjct: 1261 GPVYRLVASDLDEGLNGRVTYSIE--DSYEEAFSIDLVTGVVSSNSTFTAGEYNILTIKA 1318 Query: 658 VAIDGGTPPQSSTVIVHIK---IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 D G PP S++V +HI+ + P F+ +F + E P+ +G I Sbjct: 1319 T--DSGQPPLSASVRLHIEWIPWPRPSSIPLAFDETYYSFTVMETDPVNHMVGVISV--- 1373 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL 774 EG + ++I GGD F +E GS +V LD R Y L + Sbjct: 1374 -EGRPGLFWFNISGGDKDMDFDIEKTTGS----IVIARPLDTRR-RSNYNLTVEVTDGSR 1427 Query: 775 WNDVRVEI-LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILS 833 +V I ++ ++N + P + + +D P RV A D D L Y I Sbjct: 1428 TIATQVHIFMIANINHHRPQFLETRYEVRVPQDTVPGVELLRVQAIDQDKGKSLIYTIHG 1487 Query: 834 G---NNANLILLNETTGSMTLSPQLNT-NVPKLATMEVSVTDGVNEIK 877 +A+L L+ ++G + +L+ + P T+ V V D IK Sbjct: 1488 SQDPGSASLFQLDPSSGVLVTVGKLDLGSGPSQHTLTVMVRDQEIPIK 1535 Score = 279 bits (683), Expect = 1e-72 Identities = 238/799 (29%), Positives = 368/799 (46%), Gaps = 69/799 (8%) Query: 8 HQQINVLDCND--HSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELV 65 H ++ VLD N+ H P F ++ V+E + SGT V+ + A D D G + E++Y + Sbjct: 1015 HVEVIVLDVNENLHPPHFASFVHQGQVQENSPSGTQVIVVAAQDDDSGLDGELQYFLRAG 1074 Query: 66 TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125 T F I+ +G + T A LDRE + Y + V A D+ S Sbjct: 1075 TG-------------------LAAFSINQDTGMIQTLAPLDREFASYYWLTVLAVDRGSV 1115 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 LSS +++ + D NDN PQ S+ + S+ ED V + + ++ A D D + Sbjct: 1116 ---PLSSVTEVYIEVTDANDNPPQMSQAVFYPSIQEDAPVGTS--VLQLDAWDPDSSSKG 1170 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 + + I GN F I ++G +S + LD E + L + D G PS +T+++++ Sbjct: 1171 KLTFNITSGNYMGFFMIHPVTGLLSTAQQLDRENKDEHILEVTVLDNGEPSLKSTSRVVV 1230 Query: 246 NIRDVNDNAPRFYTSLFQESVSENV-PIGYS-IVRVQAYDADEGVNAELTYTMTDKDYTG 303 I DVNDN P F LF + E + P+ + R+ A D DEG+N +TY++ D Sbjct: 1231 GILDVNDNPPIFSHKLFNVRLPERLSPVSPGPVYRLVASDLDEGLNGRVTYSIED----- 1285 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLL-VTATDGGDPPRSATATXXXXXX---XX 359 + + +ID +G V ++ T +Y +L + ATD G PP SA+ Sbjct: 1286 SYEEAFSIDLVTGVVSSNSTF---TAGEYNILTIKATDSGQPPLSASVRLHIEWIPWPRP 1342 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG 419 F Y + E +P V ++ + I+GG+ F I + Sbjct: 1343 SSIPLAFDETYYSFTVMETDPVNHMVGVISV--EGRPGLFWFNISGGDKDMDFDI--EKT 1398 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQI-NITDANNYAPVFENAPYTASV 478 G I +A+PLD ++ Y LTV TD G R+ V I I + N++ P F Y V Sbjct: 1399 TGSIVIARPLDTRRRSNYNLTVEVTD-GSRTIATQVHIFMIANINHHRPQFLETRYEVRV 1457 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 +D G +L V A D D G + T S + + ++ F ++P +G + T Sbjct: 1458 PQDTVPGVELLRVQAIDQDKGKSLIYTIHGSQDPGSASL------FQLDPSSGVLVTVGK 1511 Query: 539 LDRET-MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LD + S + LTV RD +P + V I V D N + P F Q Y A++ + G Sbjct: 1512 LDLGSGPSQHTLTVMVRDQEIPIKRNFVWVTIHVEDGNLHPPRFTQLHYEASVPDTIAPG 1571 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 T + QV A DAD G+N +HY L K EG F I+ G+I + LD+ + A H L Sbjct: 1572 TELLQVRAMDADRGVNAEVHYSL-LKGNSEGFFNINALLGIITLAQKLDQANHAPHTLTV 1630 Query: 658 VAIDGGTPP--QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 A D G+P +TVI+H+ D S P+F I E+ P+G+ I + A P Sbjct: 1631 KAEDQGSPQWHDLATVIIHVYPSD--RSAPIFSKSEYFVEIPESIPVGSPILLVSAMSPS 1688 Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS-PPL 774 E V Y ++ G+ FS+ + G + T LD+E Y+L IR ++ Sbjct: 1689 E-----VTYELREGNKDGVFSMNSYSGL----ISTQKKLDHEK-ISSYQLKIRGSNMAGA 1738 Query: 775 WNDVRVEILVTDVNDNAPV 793 + DV V + + D NDNAP+ Sbjct: 1739 FTDVMVVVDIIDENDNAPM 1757 Score = 273 bits (670), Expect = 4e-71 Identities = 253/897 (28%), Positives = 409/897 (45%), Gaps = 70/897 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++++ D ND+ P F+ Y +++G G + + ATD+D+G N V Y Sbjct: 2057 RVSIEDVNDNPPKFKHLPYYTIIQDGTEPGDVLFQVSATDEDLGTNGAVTYEFA------ 2110 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 ED FRID G + + D + + +Y + V A D +P Sbjct: 2111 ---EDYTY------------FRIDPYLGDISLKKPFDYQALNKYHLKVIARDGGTP---S 2152 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L S + V + N + P F Y V V E+I++ P++ T A + Y Sbjct: 2153 LQSEEEVLVTV--RNKSNPLFQSPYYKVRVPENITLY-TPILH----TQARSPEGLRLIY 2205 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I+ M F+ D +G +++ LDYE + +RA D S S T ++ + D Sbjct: 2206 NIVEEEPLMLFTTDFKTGVLTVTGPLDYESKTKHVFTVRATDTALGSFSEATVEVL-VED 2264 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 VNDN P F ++ S+SE +P ++++ A D D G N +++Y + + +V Sbjct: 2265 VNDNPPTFSQLVYTTSISEGLPAQTPVIQLLASDQDSGRNRDVSYQIVEDG--SDVSKFF 2322 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 I+ +G + T +LD E Q + + V A D GDPP + F Sbjct: 2323 QINGSTGEMSTVQELDYEAQQHFHVKVRAMDKGDPPLTGETLVVVNVSDINDNPPEFRQP 2382 Query: 370 QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 QYE ++E G V+ + A D D + +RL Y I GN F I S +G +I++ Sbjct: 2383 QYEANVSELATCGHLVLKVQAIDPDSRDTSRLEYLILSGNQDRHFFINSSSG--IISMFN 2440 Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 + Y L V A+D R+ T V IN T+AN Y+P F+ Y A + E+A +GT Sbjct: 2441 LCKKHLDSSYNLRVGASDGVFRA-TVPVYINTTNANKYSPEFQQHLYEAELAENAMVGTK 2499 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 V+ + A D D G I Y++ +++++E +F INP G I T + LDRE + Sbjct: 2500 VIDLLAIDKDSGPYGTIDYTIINKLASE-------KFSINPN-GQIATLQKLDRENSTER 2551 Query: 548 LLT--VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 ++ V ARDGG T V+I + D NDN P FK YT +I + + V QV A Sbjct: 2552 VIAIKVMARDGGGRVAFCT--VKIILTDENDNPPQFKASEYTVSIQSNVSKDSPVIQVLA 2609 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 DAD G N + Y ++P+D + I+P +GV++ +L T D A DGG P Sbjct: 2610 YDADEGQNADVTYSVNPEDLVKDVIEINPVTGVVKVKDSLVGLENQTLDFFIKAQDGGPP 2669 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 +S V V +++ S P F TF E+ P G+ IG ++A + V++ Sbjct: 2670 HWNSLVPVRLQVVPKKVSLPKFSEPLYTFSAPEDLPEGSEIGIVKA---VAAQDPVIYSL 2726 Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEI 782 ++G ++ D + +D+ES K Y++ + A + + + V V I Sbjct: 2727 VRGTTPESNKDGVFSLDPDTGVIKVRKPMDHES-TKLYQIDVMAHCLQNTDVVSLVSVNI 2785 Query: 783 LVTDVNDNAPVMK--DFQIIFNNYKDCFPVG-PFGRVPAYDADV--TDKLQYRILS--GN 835 V DVNDN PV + ++ + + PVG +V A D D ++ YR+ + G+ Sbjct: 2786 QVGDVNDNRPVFEADPYKAVLT---ENMPVGTSVIQVTAIDKDTGRDGQVSYRLSADPGS 2842 Query: 836 NAN-LILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL-ITEE 890 N + L ++ +G +T +L+ + V D I+ Q V++ IT+E Sbjct: 2843 NVHELFAIDSESGWITTLQELDCETCQTYHFHVVAYDHGQTIQLSSQALVQVSITDE 2899 Score = 271 bits (664), Expect = 2e-70 Identities = 253/902 (28%), Positives = 409/902 (45%), Gaps = 60/902 (6%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 VF +D +G + R +D E Y + V A +D + S ++++ + D NDN P Sbjct: 2739 VFSLDPDTGVIKVRKPMDHESTKLYQIDVMA--HCLQNTD-VVSLVSVNIQVGDVNDNRP 2795 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII---GGNTQMQFSIDSL 205 F Y + E++ V + + ++ A D D G + + Y + G N F+IDS Sbjct: 2796 VFEADPYKAVLTENMPVGTS--VIQVTAIDKDTGRDGQVSYRLSADPGSNVHELFAIDSE 2853 Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIRDVNDNAPRFYTSLFQE 264 SG ++ ++ LD E ++Y + A D G + ++ L+ ++I D NDNAPRF + ++ Sbjct: 2854 SGWITTLQELDCETCQTYHFHVVAYDHGQTIQLSSQALVQVSITDENDNAPRFASEEYRG 2913 Query: 265 SVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323 SV EN G + ++ DAD N ++T +T+ D G + D W +S + Sbjct: 2914 SVVENSEPGELVATLKTLDADISEQNRQVTCYITEGDPLGQFGISQVGDE---WRISSRK 2970 Query: 324 -LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382 LDRE AKY L VTA+DG A+ T Y ++ ED PG Sbjct: 2971 TLDREHTAKYLLRVTASDG---KFQASVTVEIFVLDVNDNSPQCSQLLYTGKVHEDVFPG 3027 Query: 383 TPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440 ++ ++ATD D D ++ Y + G F + G +T LD +++ + L Sbjct: 3028 HFILKVSATDLDTDTNAQITYSLHGPGAH-EFKLDPHTGE--LTTLTALDRERKDVFNLV 3084 Query: 441 VSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 ATD GGRS A + +++ D N+ AP F + +VF++ + T V VV A D D G Sbjct: 3085 AKATDGGGRSCQADITLHVEDVNDNAPRFFPSHCAVAVFDNTTVKTPVAVVFARDPDQGA 3144 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP- 559 NAQ+ YSL + A H F I+ TG I K L + LTV A D G P Sbjct: 3145 NAQVVYSLP----DSAEGH----FSIDATTGVIRLEKPLQVRPQAPLELTVRASDLGTPI 3196 Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619 LS V +SVV + D PVF ++ + EDA GT V Q+ AT G + Y Sbjct: 3197 PLSTLGTVTVSVVGLEDYLPVFLNTEHSVQVPEDAPPGTEVLQL-ATLTRPGAE-KTGYR 3254 Query: 620 LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679 + E+G F +D +G++ N +LD E+ + L + S V + I D Sbjct: 3255 V-VSGNEQGRFRLDARTGILYVNASLDFETSPKYFLSIECSRKSSSSLSDVTTVMVNITD 3313 Query: 680 INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLET 739 +N+ P F D + + EN+ +G I + A D D N+ + YS+ GG+ F++ Sbjct: 3314 VNEHRPQFPQDPYSTRVLENALVGDVILTVSATDEDGPLNSDITYSLIGGNQLGHFTIHP 3373 Query: 740 RQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKD 796 ++G EL LD E Y L +RA PPL D + I V DVNDN P + Sbjct: 3374 KKG----ELQVAKALDREQ-ASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPP--RF 3426 Query: 797 FQIIFN-NYKDCFPVG-PFGRVPAYDADVTDK---LQYRILSGNNANLILLNETTGSMTL 851 FQ+ ++ ++ P+G ++ D D + +RI GNN + + G + Sbjct: 3427 FQLNYSTTVQENSPIGSKVLQLILSDPDSPENGPPYSFRITKGNNGSAFRVT-PDGWLVT 3485 Query: 852 SPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLS 910 + L+ + +++ +D G+ + ++ + V +TE+ + L ++ Sbjct: 3486 AEGLSRRAQEWYQLQIQASDSGIPPLSSLTSVRVH-VTEQSHYAPSALPL-EIFITVGED 3543 Query: 911 PLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVA-GDPSPH 969 G + + A P++ + +++T L FS PD ++ A G P H Sbjct: 3544 EFQGGMVGKIHATDRDPQDTLTYSLAEEET------LGRHFSVGAPDGKIIAAQGLPRGH 3597 Query: 970 YS 971 YS Sbjct: 3598 YS 3599 Score = 259 bits (634), Expect = 9e-67 Identities = 235/862 (27%), Positives = 377/862 (43%), Gaps = 71/862 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D ND+SP + V E GT + L A+D D+G EV Y + Sbjct: 913 ITLEDVNDNSPQCITEHNRLKVPEDLPPGTVLTFLDASDPDLGPAGEVRYVL-------- 964 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 FR+D +GAL+ LD E+ A Y + + A+D P++ R Sbjct: 965 ------------MDGAHGTFRVDLMTGALILERELDFERRAGYNLSLWASDGGRPLARRT 1012 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + V +++N + P F+ + V E+ S + VI + A D D G + ++Y Sbjct: 1013 LCHVEVIVLDVNENLHPPHFASFVHQGQVQEN-SPSGTQVIV-VAAQDDDSGLDGELQYF 1070 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + G FSI+ +G + + LD E Y L + A D GS S+ T++ I + D Sbjct: 1071 LRAGTGLAAFSINQDTGMIQTLAPLDREFASYYWLTVLAVDRGSVPLSSVTEVYIEVTDA 1130 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P+ ++F S+ E+ P+G S++++ A+D D +LT+ +T +Y G Sbjct: 1131 NDNPPQMSQAVFYPSIQEDAPVGTSVLQLDAWDPDSSSKGKLTFNITSGNYMGF----FM 1186 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I P +G + T+ QLDRE + ++ L VT D G+P +T+ F Sbjct: 1187 IHPVTGLLSTAQQLDRENKDEHILEVTVLDNGEPSLKSTSRVVVGILDVNDNPPIFSHKL 1246 Query: 371 YEVELAEDEPPGT--PVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 + V L E P + PV L A+D DE + R+ Y I FSI G V+ Sbjct: 1247 FNVRLPERLSPVSPGPVYRLVASDLDEGLNGRVTYSIEDSYEEA-FSIDLVTG----VVS 1301 Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQINI-----TDANNYAPVFENAPYTASVFED 481 F +LT+ ATDSG +A V+++I ++ F+ Y+ +V E Sbjct: 1302 SNSTFTAGEYNILTIKATDSGQPPLSASVRLHIEWIPWPRPSSIPLAFDETYYSFTVMET 1361 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 P+ V V+S G +++S D F I TG+I + LD Sbjct: 1362 DPVNHMVGVISVE----GRPGLFWFNISG-------GDKDMDFDIEKTTGSIVIARPLDT 1410 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEI-SVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 S Y LTV DG S + T V I + ++N + P F + Y + +D + G + Sbjct: 1411 RRRSNYNLTVEVTDG---SRTIATQVHIFMIANINHHRPQFLETRYEVRVPQDTVPGVEL 1467 Query: 601 SQVGATDADVG--LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES-VATHDLKA 657 +V A D D G L IH DP F +DP+SGV+ T LD S + H L Sbjct: 1468 LRVQAIDQDKGKSLIYTIHGSQDP--GSASLFQLDPSSGVLVTVGKLDLGSGPSQHTLTV 1525 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 + D P + + V V I +ED N PP F + + GT + ++RA D D G Sbjct: 1526 MVRDQEIPIKRNFVWVTIHVEDGNLHPPRFTQLHYEASVPDTIAPGTELLQVRAMDADRG 1585 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA--ASPPLW 775 NA VHYS+ G+ F++ G ++T+ ++ + L ++A P W Sbjct: 1586 VNAEVHYSLLKGNSEGFFNINALLG-----IITLAQKLDQANHAPHTLTVKAEDQGSPQW 1640 Query: 776 NDVRVEILVTDVND-NAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSG 834 +D+ I+ +D +AP+ + F + PVG + A ++ Y + G Sbjct: 1641 HDLATVIIHVYPSDRSAPIFSKSE-YFVEIPESIPVG--SPILLVSAMSPSEVTYELREG 1697 Query: 835 NNANLILLNETTGSMTLSPQLN 856 N + +N +G ++ +L+ Sbjct: 1698 NKDGVFSMNSYSGLISTQKKLD 1719 Score = 254 bits (623), Expect = 2e-65 Identities = 248/879 (28%), Positives = 394/879 (44%), Gaps = 86/879 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+V D N H P F YEASV + + GT +L ++A D D G NAEV Y+ L+ ++ Sbjct: 1543 IHVEDGNLHPPRFTQLHYEASVPDTIAPGTELLQVRAMDADRGVNAEVHYS--LLKGNS- 1599 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F I+ G + LD+ A +T+ VKA DQ SP + Sbjct: 1600 ----------------EGFFNINALLGIITLAQKLDQANHAPHTLTVKAEDQGSP---QW 1640 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 AT+ +++ + + P FS+ Y V + E I V +P++ + S + Y Sbjct: 1641 HDLATVIIHVYPSDRSAPIFSKSEYFVEIPESIPV-GSPILL------VSAMSPSEVTYE 1693 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + GN FS++S SG +S K LD+E++ SY+L IR + ++++I D Sbjct: 1694 LREGNKDGVFSMNSYSGLISTQKKLDHEKISSYQLKIRGSN--MAGAFTDVMVVVDIIDE 1751 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVR--------VQAYDADEGVNAELTYTMTDKDYT 302 NDNAP F S F +SE P+ YS++ + A D+D+ N+ L Y + + + Sbjct: 1752 NDNAPMFLKSTFVGQISEAAPL-YSMIMDKNNNPFVIHASDSDKEANSLLVYKILEPEAL 1810 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT--ATXXXXXXXXX 360 IDP G + ++D E+ +Q V D G P A A Sbjct: 1811 KF----FKIDPSMGTLTIVSEMDYESMPSFQFCVYVHDQGSPVLFAPRPAQVIIHVRDVN 1866 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420 F YEV + PG ++ + A+D ED+ ++Y I GN ++T Sbjct: 1867 DSPPRFSEQIYEVAIVGPIHPGMELLMVRASD--EDSEVNYSIKTGNADE--AVTIHPVT 1922 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 G I+V P R+ LT+ A+D G DTA+V+I++T + + F+ Y A+V E Sbjct: 1923 GSISVLNPAFLGLSRK--LTIRASD-GLYQDTALVKISLTQVLDKSLQFDQDVYWAAVKE 1979 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL-L 539 + ++++ A + +N ++Y L ++ + H Q G + T + Sbjct: 1980 NLQDRKALVILGAQGNH--LNDTLSYFL---LNGTDMFHMVQS------AGVLQTRGVAF 2028 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 DRE + L V RD P V +S+ DVNDN P FK Y I + G Sbjct: 2029 DREQQDTHELAVEVRDNRTPQRVAQGLVRVSIEDVNDNPPKFKHLPYYTIIQDGTEPGDV 2088 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 + QV ATD D+G NG + YE + F IDP G I K D +++ + LK +A Sbjct: 2089 LFQVSATDEDLGTNGAVTYEF---AEDYTYFRIDPYLGDISLKKPFDYQALNKYHLKVIA 2145 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 DGGTP S V + + N S P+F+S + EN + T I +A P EG Sbjct: 2146 RDGGTPSLQSEEEVLVTVR--NKSNPLFQSPYYKVRVPENITLYTPILHTQARSP-EGLR 2202 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL--WND 777 + Y+I + F+ + + G L LDYES + K+ +RA L +++ Sbjct: 2203 LI--YNIVEEEPLMLFTTDFKTG----VLTVTGPLDYES-KTKHVFTVRATDTALGSFSE 2255 Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVPAYDADV--TDKLQYRILSG 834 VE+LV DVNDN P + + + P P ++ A D D + Y+I+ Sbjct: 2256 ATVEVLVEDVNDNPPTFSQL-VYTTSISEGLPAQTPVIQLLASDQDSGRNRDVSYQIVED 2314 Query: 835 NN--ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + + +N +TG M+ +L+ + ++V D Sbjct: 2315 GSDVSKFFQINGSTGEMSTVQELDYEAQQHFHVKVRAMD 2353 Score = 222 bits (542), Expect = 1e-55 Identities = 161/528 (30%), Positives = 262/528 (49%), Gaps = 29/528 (5%) Query: 373 VELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 +++ E P TP+ L ATD D + +L Y I GN G F I + G L+TVA PLD Sbjct: 722 IDVLESVPINTPLARLAATDPDAGFNGKLVYVIADGNEEGCFDIELETG--LLTVAAPLD 779 Query: 431 FKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 ++ Y+L V+ D G +S ++ +N+ D N+ AP F Y ++ ED +GTT+ Sbjct: 780 YEATNFYILNVTVYDLGTPQKSSWKLLTVNVKDWNDNAPRFPPGGYQLTISEDTEVGTTI 839 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 ++ D+D N ++ Y+L S ++F ++P TG + LDRE+ Y+ Sbjct: 840 AELTTKDADSEDNGRVRYTLLSP---------TEKFSLHPLTGELVVTGHLDRESEPRYI 890 Query: 549 LTVTARD--GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 L V ARD L TD+ I++ DVNDN P + + ED GT ++ + A+ Sbjct: 891 LKVEARDQPSKGHQLFSVTDLIITLEDVNDNSPQCITEHNRLKVPEDLPPGTVLTFLDAS 950 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D D+G G + Y L D G+F +D +G + + LD E A ++L A DGG P Sbjct: 951 DPDLGPAGEVRYVL--MDGAHGTFRVDLMTGALILERELDFERRAGYNLSLWASDGGRPL 1008 Query: 667 QSSTVI-VHIKIEDINDS--PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 T+ V + + D+N++ PP F S + ENSP GT + + A D D G + + Sbjct: 1009 ARRTLCHVEVIVLDVNENLHPPHFASFVHQGQVQENSPSGTQVIVVAAQDDDSGLDGELQ 1068 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEIL 783 Y ++ G +FS+ Q + + + +D ++ S L + S PL + V I Sbjct: 1069 YFLRAGTGLAAFSI--NQDTGMIQTLAPLDREFASYYWLTVLAVDRGSVPLSSVTEVYIE 1126 Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTD--KLQYRILSGNNANLI 840 VTD NDN P M + + + ++ PVG ++ A+D D + KL + I SGN Sbjct: 1127 VTDANDNPPQMSQ-AVFYPSIQEDAPVGTSVLQLDAWDPDSSSKGKLTFNITSGNYMGFF 1185 Query: 841 LLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLI 887 +++ TG ++ + QL+ +EV+V D G +K+ ++ V ++ Sbjct: 1186 MIHPVTGLLSTAQQLDRENKDEHILEVTVLDNGEPSLKSTSRVVVGIL 1233 Score = 187 bits (456), Expect = 3e-45 Identities = 127/374 (33%), Positives = 184/374 (49%), Gaps = 16/374 (4%) Query: 87 QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146 Q FR+D R+G L ASLD E +Y + ++ + ++S LS T+ VNI D N++ Sbjct: 3261 QGRFRLDARTGILYVNASLDFETSPKYFLSIECSRKSS---SSLSDVTTVMVNITDVNEH 3317 Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206 PQF + Y+ V E+ V D VI + ATD D NS I Y++IGGN F+I Sbjct: 3318 RPQFPQDPYSTRVLENALVGD--VILTVSATDEDGPLNSDITYSLIGGNQLGHFTIHPKK 3375 Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266 G++ + K LD EQ SY L +RA D G P T + I + DVNDN PRF+ + +V Sbjct: 3376 GELQVAKALDREQASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPPRFFQLNYSTTV 3435 Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326 EN PIG ++++ D D N Y+ + GN + P GW+ T+ L R Sbjct: 3436 QENSPIGSKVLQLILSDPDSPENGP-PYSF--RITKGNNGSAFRVTP-DGWLVTAEGLSR 3491 Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386 Q YQL + A+D G PP S+ + +P + + + EDE G V Sbjct: 3492 RAQEWYQLQIQASDSGIPPLSSLTSVRVHVTEQSHYAPSALPLEIFITVGEDEFQGGMVG 3551 Query: 387 TLTATDADEDNRLHYEITGGNTRGR-FSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445 + ATD D + L Y + T GR FS+ + +G+ I AQ L Y V+ +D Sbjct: 3552 KIHATDRDPQDTLTYSLAEEETLGRHFSVGAPDGK--IIAAQGL---PRGHYSFNVTVSD 3606 Query: 446 SGGRSDTAMVQINI 459 G + TA V + + Sbjct: 3607 -GTFTTTAGVHVYV 3619 Score = 150 bits (363), Expect = 6e-34 Identities = 129/418 (30%), Positives = 197/418 (47%), Gaps = 32/418 (7%) Query: 450 SDTAMVQINITDANNYAPVFENA-PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508 SD ++ N+Y P FE+ P + V E PI T + ++ATD D G N ++ Y + Sbjct: 695 SDEEFTSLSTYQINHYTPQFEDHFPQSIDVLESVPINTPLARLAATDPDAGFNGKLVYVI 754 Query: 509 SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568 + NE + F I +TG +T LD E + Y+L VT D G P S + Sbjct: 755 AD--GNE-----EGCFDIELETGLLTVAAPLDYEATNFYILNVTVYDLGTPQKSSWKLLT 807 Query: 569 ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE-LDPKDREE 627 ++V D NDN P F Y I ED VGT+++++ DAD NGR+ Y L P ++ Sbjct: 808 VNVKDWNDNAPRFPPGGYQLTISEDTEVGTTIAELTTKDADSEDNGRVRYTLLSPTEK-- 865 Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS--STVIVHIKIEDINDSPP 685 F + P +G + LDRES + LK A D + S + I +ED+ND+ P Sbjct: 866 --FSLHPLTGELVVTGHLDRESEPRYILKVEARDQPSKGHQLFSVTDLIITLEDVNDNSP 923 Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745 ++ + E+ P GT + + A DPD GP V Y + G +F ++ G+ Sbjct: 924 QCITEHNRLKVPEDLPPGTVLTFLDASDPDLGPAGEVRYVLMDG-AHGTFRVDLMTGA-- 980 Query: 746 AELVTMVDLDYESPRKKYELVIRAA--SPPLWNDV--RVEILVTDVNDN--APVMKDFQI 799 L+ +LD+E R Y L + A+ PL VE++V DVN+N P F + Sbjct: 981 --LILERELDFER-RAGYNLSLWASDGGRPLARRTLCHVEVIVLDVNENLHPPHFASF-V 1036 Query: 800 IFNNYKDCFPVGPFGRVPAY---DADVTDKLQYRILSGNNANLILLNETTGSM-TLSP 853 ++ P G V A D+ + +LQY + +G +N+ TG + TL+P Sbjct: 1037 HQGQVQENSPSGTQVIVVAAQDDDSGLDGELQYFLRAGTGLAAFSINQDTGMIQTLAP 1094 Score = 148 bits (359), Expect = 2e-33 Identities = 165/630 (26%), Positives = 270/630 (42%), Gaps = 45/630 (7%) Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE-DISVTDNPVIAKIKATDADVGA 183 P+ LSS+A + + Y S KTY S ++ I + + + + DV Sbjct: 21 PLEGILSSSAWHFTHSHYNATIYENSSPKTYVESFEKMGIYLAEPQWAVRYRIISGDVAN 80 Query: 184 NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 ++G ++ I + S + +L L+ E SY L+I+A + + T++ Sbjct: 81 VFKTEEYVVGNFCFLR--IRTKSSNTAL---LNREVRDSYTLIIQATEKTLELEA-LTRV 134 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 +++I D ND P F ++ ++SE++P+ I +V A DAD G NAE Y + Sbjct: 135 VVHILDQNDLKPLFSPPSYRVTISEDMPLKSPICKVTATDADLGQNAEFYYAFNTRSEM- 193 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 I P SG V +G+L+ + K++L V A D Sbjct: 194 -----FAIHPTSGVVTVAGKLNVTWRGKHELQVLAVDRMRKISEGNGFGSLAALVVHVEP 248 Query: 364 XXFMPGQYE--VELAEDEPPGTPVVT-LTATDADEDNRLHYEITGGNTRGRF----SITS 416 P V D GT T L ++ E+ GG+ F S Sbjct: 249 ALRKPPAIASVVVTPPDSNDGTTYATVLVDANSSGAEVESVEVVGGDPGKHFKAIKSYAR 308 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ-INITDANNYAPVFENAPYT 475 N L++V + + L++ A G + ++ ++ + + FE A Y Sbjct: 309 SNEFSLVSVKDINWMEYLHGFNLSLQARSGSGPYFYSQIRGFHLPPSKLSSLKFEKAVYR 368 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 + E +P G+ V++V T + N Q SSE + F +N +TG ITT Sbjct: 369 VQLSEFSPPGSRVVMVRVTPAFP--NLQYVLKPSSE---------NVGFKLNARTGLITT 417 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 KL+D + Y L + G +T V I +VD N++ P+F + Y + E+ Sbjct: 418 TKLMDFHDRAHYQLHIRTSPG-----QASTVVVIDIVDCNNHAPLFNRSSYDGTLDENIP 472 Query: 596 VGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFVIDPASGVIRTNKALDRESV-ATH 653 GTSV V ATD D G NG + Y + PK F IDP G+I T+K +D E + + Sbjct: 473 PGTSVLAVTATDRDHGENGYVTYSIAGPKAL---PFSIDPYLGIISTSKPMDYELMKRIY 529 Query: 654 DLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 + A D G+P + V + +++ ++ND+ P+FE T I ++ P+G +I + A Sbjct: 530 TFRVRASDWGSPFRREKEVSIFLQLRNLNDNQPMFEEVNCTGSIRQDWPVGKSIMTMSAI 589 Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 D DE N + Y I G++ F L G Sbjct: 590 DVDELQN--LKYEIVSGNELEYFDLNHFSG 617 Score = 128 bits (309), Expect = 2e-27 Identities = 141/567 (24%), Positives = 238/567 (41%), Gaps = 42/567 (7%) Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383 L+RE + Y L++ AT+ + T F P Y V ++ED P + Sbjct: 107 LNREVRDSYTLIIQATEKTLELEALTRVVVHILDQNDLKPL-FSPPSYRVTISEDMPLKS 165 Query: 384 PVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443 P+ +TATDAD + F+I +G ++TVA L+ ++ L V A Sbjct: 166 PICKVTATDADLGQNAEFYYAFNTRSEMFAIHPTSG--VVTVAGKLNVTWRGKHELQVLA 223 Query: 444 TD-------SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496 D G A + +++ A P + T D+ GTT V + Sbjct: 224 VDRMRKISEGNGFGSLAALVVHVEPALRKPPAIASVVVTPP---DSNDGTTYATVLVDAN 280 Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556 G + + + A + + + + ++ + E + G+ L++ AR G Sbjct: 281 SSGAEVESVEVVGGDPGKHFKAI--KSYARSNEFSLVSVKDINWMEYLHGFNLSLQARSG 338 Query: 557 GVPSL-SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615 P S + ++ + F++ +Y + E + G+ V V T A L Sbjct: 339 SGPYFYSQIRGFHLPPSKLSSLK--FEKAVYRVQLSEFSPPGSRVVMVRVTPAFPNLQ-- 394 Query: 616 IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675 Y L P G F ++ +G+I T K +D A + L +P Q+STV+V I Sbjct: 395 --YVLKPSSENVG-FKLNARTGLITTTKLMDFHDRAHYQLHIRT----SPGQASTVVV-I 446 Query: 676 KIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735 I D N+ P+F + EN P GT++ + A D D G N V YSI G + F Sbjct: 447 DIVDCNNHAPLFNRSSYDGTLDENIPPGTSVLAVTATDRDHGENGYVTYSI-AGPKALPF 505 Query: 736 SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA--SPPLWNDVRVEIL--VTDVNDNA 791 S++ G + T +DYE ++ Y +RA+ P + V I + ++NDN Sbjct: 506 SIDPYLGI----ISTSKPMDYELMKRIYTFRVRASDWGSPFRREKEVSIFLQLRNLNDNQ 561 Query: 792 PVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMT 850 P+ ++ + +D +PVG + A D D L+Y I+SGN LN +G ++ Sbjct: 562 PMFEEVNCTGSIRQD-WPVGKSIMTMSAIDVDELQNLKYEIVSGNELEYFDLNHFSGVIS 620 Query: 851 LS-PQLNTNV--PKLATMEVSVTDGVN 874 L P +N P +++++ +DG N Sbjct: 621 LKRPFINLTAGQPTSYSLKITASDGKN 647 Score = 128 bits (309), Expect = 2e-27 Identities = 102/326 (31%), Positives = 164/326 (50%), Gaps = 24/326 (7%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV 425 F Y V+L+E PPG+ VV + T A + L Y + + F + ++ G LIT Sbjct: 362 FEKAVYRVQLSEFSPPGSRVVMVRVTPAFPN--LQYVLKPSSENVGFKLNARTG--LITT 417 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 + +DF Y L + S G++ T +V I+I D NN+AP+F + Y ++ E+ P G Sbjct: 418 TKLMDFHDRAHYQLHIRT--SPGQASTVVV-IDIVDCNNHAPLFNRSSYDGTLDENIPPG 474 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 T+VL V+ATD D G N +TYS++ +A+ F I+P G I+T+K +D E M Sbjct: 475 TSVLAVTATDRDHGENGYVTYSIAGP---KAL-----PFSIDPYLGIISTSKPMDYELMK 526 Query: 546 G-YLLTVTARDGGVPSLSD-TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 Y V A D G P + + + + ++NDN+P+F++ T +I +D VG S+ + Sbjct: 527 RIYTFRVRASDWGSPFRREKEVSIFLQLRNLNDNQPMFEEVNCTGSIRQDWPVGKSIMTM 586 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA---LDRESVATHDLKAVAI 660 A D D N + YE+ E F ++ SGVI + L ++ LK A Sbjct: 587 SAIDVDELQN--LKYEI-VSGNELEYFDLNHFSGVISLKRPFINLTAGQPTSYSLKITAS 643 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPV 686 DG +T+ + + ++D + PV Sbjct: 644 DGKNYASPTTLNITV-VKDPHFEVPV 668 Score = 107 bits (256), Expect = 6e-21 Identities = 80/279 (28%), Positives = 136/279 (48%), Gaps = 19/279 (6%) Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 ++Y + + + F +++ +G ++ K +D+ Y+L IR SP +++T ++I+ Sbjct: 393 LQYVLKPSSENVGFKLNARTGLITTTKLMDFHDRAHYQLHIRT----SPGQASTV-VVID 447 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 I D N++AP F S + ++ EN+P G S++ V A D D G N +TY++ G Sbjct: 448 IVDCNNHAPLFNRSSYDGTLDENIPPGTSVLAVTATDRDHGENGYVTYSI-----AGPKA 502 Query: 307 LPITIDPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDP-PRSATATXXXXXXXXXXXXX 364 LP +IDP G + TS +D E + Y V A+D G P R + Sbjct: 503 LPFSIDPYLGIISTSKPMDYELMKRIYTFRVRASDWGSPFRREKEVSIFLQLRNLNDNQP 562 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLIT 424 F + +D P G ++T++A D DE L YEI GN F + + G+I+ Sbjct: 563 MFEEVNCTGSIRQDWPVGKSIMTMSAIDVDELQNLKYEIVSGNELEYFDL--NHFSGVIS 620 Query: 425 VAQP---LDFKQERRYVLTVSATDSGGRSDTAMVQINIT 460 + +P L Q Y L ++A+D G++ + +NIT Sbjct: 621 LKRPFINLTAGQPTSYSLKITASD--GKNYASPTTLNIT 657 Score = 105 bits (253), Expect = 1e-20 Identities = 139/579 (24%), Positives = 247/579 (42%), Gaps = 72/579 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +++LD ND P+F Y ++ E + + + ATD D+G+NAE Y Sbjct: 136 VHILDQNDLKPLFSPPSYRVTISEDMPLKSPICKVTATDADLGQNAEFYYAFN------- 188 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD-- 128 ++F I SG + L+ ++ + V A D+ +S+ Sbjct: 189 --------------TRSEMFAIHPTSGVVTVAGKLNVTWRGKHELQVLAVDRMRKISEGN 234 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 S A + V++ P + T D + T V+ ++ A+V + Sbjct: 235 GFGSLAALVVHVEPALRKPPAIASVVVT-PPDSNDGTTYATVLVDANSSGAEVES----- 288 Query: 189 YAIIGGNTQMQF-SIDSL--SGDVSLVKTLD---YEQVRSYRLVIRAQDGGSPSRSNTTQ 242 ++GG+ F +I S S + SLV D E + + L ++A+ G P + + Sbjct: 289 VEVVGGDPGKHFKAIKSYARSNEFSLVSVKDINWMEYLHGFNLSLQARSGSGPYFYSQIR 348 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 ++ ++ +F ++++ +SE P G +V V+ A L Y + K + Sbjct: 349 -GFHLPPSKLSSLKFEKAVYRVQLSEFSPPGSRVVMVRVTPA----FPNLQYVL--KPSS 401 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 NV ++ R+G + T+ +D +A YQL + + P A+ Sbjct: 402 ENVG--FKLNARTGLITTTKLMDFHDRAHYQLHIRTS-----PGQASTVVVIDIVDCNNH 454 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGR 420 F Y+ L E+ PPGT V+ +TATD D E+ + Y I G FSI Sbjct: 455 APLFNRSSYDGTLDENIPPGTSVLAVTATDRDHGENGYVTYSIAGPKAL-PFSIDPY--L 511 Query: 421 GLITVAQPLDFK-QERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTA 476 G+I+ ++P+D++ +R Y V A+D G R + + + + N+ P+FE T Sbjct: 512 GIISTSKPMDYELMKRIYTFRVRASDWGSPFRREKEVSIFLQLRNLNDNQPMFEEVNCTG 571 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 S+ +D P+G +++ +SA D D N + Y + S NE + F +N +G I+ Sbjct: 572 SIRQDWPVGKSIMTMSAIDVDELQN--LKYEIVS--GNEL-----EYFDLNHFSGVISLK 622 Query: 537 KLLDRETM---SGYLLTVTARDGGVPSLSDTTDVEISVV 572 + T + Y L +TA DG + + T + I+VV Sbjct: 623 RPFINLTAGQPTSYSLKITASDG--KNYASPTTLNITVV 659 Score = 93.9 bits (223), Expect = 6e-17 Identities = 76/249 (30%), Positives = 118/249 (47%), Gaps = 31/249 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+++DCN+H+P+F Y+ ++ E GT+VL + ATD+D G+N V Y+I Sbjct: 446 IDIVDCNNHAPLFNRSSYDGTLDENIPPGTSVLAVTATDRDHGENGYVTYSI-------A 498 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSDR 129 P+ F ID G + T +D E + R YT V+A+D SP R Sbjct: 499 GPKAL-------------PFSIDPYLGIISTSKPMDYELMKRIYTFRVRASDWGSPF--R 543 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 +I + + + NDN P F E T S+ +D V + I + A D D N ++Y Sbjct: 544 REKEVSIFLQLRNLNDNQPMFEEVNCTGSIRQDWPVGKS--IMTMSAIDVDELQN--LKY 599 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVK---TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 I+ GN F ++ SG +SL + L Q SY L I A DG + + T + + Sbjct: 600 EIVSGNELEYFDLNHFSGVISLKRPFINLTAGQPTSYSLKITASDGKNYASPTTLNITV- 658 Query: 247 IRDVNDNAP 255 ++D + P Sbjct: 659 VKDPHFEVP 667 Score = 62.1 bits (144), Expect = 2e-07 Identities = 44/130 (33%), Positives = 72/130 (55%), Gaps = 10/130 (7%) Query: 103 ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162 A L+RE YT++++AT++ L + + V+I+D ND P FS +Y V++ ED Sbjct: 105 ALLNREVRDSYTLIIQATEKTL----ELEALTRVVVHILDQNDLKPLFSPPSYRVTISED 160 Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ-FSIDSLSGDVSLVKTLDYEQVR 221 + + +P I K+ ATDAD+G N+ YA NT+ + F+I SG V++ L+ Sbjct: 161 MPL-KSP-ICKVTATDADLGQNAEFYYAF---NTRSEMFAIHPTSGVVTVAGKLNVTWRG 215 Query: 222 SYRLVIRAQD 231 + L + A D Sbjct: 216 KHELQVLAVD 225 Score = 44.4 bits (100), Expect = 0.046 Identities = 66/255 (25%), Positives = 102/255 (40%), Gaps = 51/255 (20%) Query: 1103 CELRARSFPVSSFLTF--PGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELV 1160 C A F S++ + P + H IH LK T +LL+ NE ++L+L Sbjct: 3771 CNGTATRFSGQSYVRYRAPAARNWH-IHFYLK--TLQPQAILLFT---NETAS-VSLKLA 3823 Query: 1161 SSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKVLS 1220 S G P L + LGG ++ + +V D WH++ +E + +I +++D Sbjct: 3824 S------GVPQLEYH-CLGGFYGNLSSQRHVNDHEWHSILVEEMDASIRLMVDSMGN--- 3873 Query: 1221 LAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIPSSFQVKNKD 1280 T V+P C R L L +GGL + SS V ++ Sbjct: 3874 ----------------TSLVVPENC--------RGLRPERHLLLGGLILLHSSSNV-SQG 3908 Query: 1281 FVGCISDFYIDHKFIDL---NSYVA---DNGTLAGCPEKRSRCSSAPCYNGAECSDLWDT 1334 F GC+ ++ + +DL VA + L C CS C NG +CS Sbjct: 3909 FEGCLDAVVVNEEALDLLAPGKTVAGLLETQALTQCCLHSDYCSQNTCLNGGKCSWTHGA 3968 Query: 1335 -YICDCKEGHTGKDC 1348 Y+C C +GK C Sbjct: 3969 GYVCKCPPQFSGKHC 3983 Score = 38.7 bits (86), Expect = 2.3 Identities = 61/263 (23%), Positives = 98/263 (37%), Gaps = 34/263 (12%) Query: 1343 HTGKDCADSTGPPWRFGGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVM--------S 1394 H + C+ G RF G + + P W ++T Q A ++ S Sbjct: 3764 HLQRSCS-CNGTATRFSGQSYVRYRA---PAARNWHIHFYLKTLQPQAILLFTNETASVS 3819 Query: 1395 IQLKSGLLHYSYNG-ETMYLPMAT---LSDGAWHRIEIKWLGTDISVTVD-YGLRTVLMP 1449 ++L SG+ Y+ Y +++ ++D WH I ++ + I + VD G ++++P Sbjct: 3820 LKLASGVPQLEYHCLGGFYGNLSSQRHVNDHEWHSILVEEMDASIRLMVDSMGNTSLVVP 3879 Query: 1450 MLANKIQGQYIGKILIGGLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRP------TV 1503 ++ + +L+GGL GF EGC+ V + L P + Sbjct: 3880 ENCRGLRPER--HLLLGGLILLHSSSNVSQGF-EGCLDAVVVNEEALDLLAPGKTVAGLL 3936 Query: 1504 RENVRDGCQSRAD-CMLSICPPYSKCV-TSWDSSTCTCEAGRVGPQCVSA---CELGPC- 1557 C +D C + C KC T C C G C C PC Sbjct: 3937 ETQALTQCCLHSDYCSQNTCLNGGKCSWTHGAGYVCKCPPQFSGKHCEQGRENCTFAPCL 3996 Query: 1558 GAARCVPDQTPKGYSCACEPGYT 1580 C+ +PKG SC C YT Sbjct: 3997 EGGTCI--LSPKGASCNCPHPYT 4017 Score = 37.5 bits (83), Expect = 5.3 Identities = 38/166 (22%), Positives = 65/166 (39%), Gaps = 7/166 (4%) Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAEL-----VTMVDLDYESPRKKYELVIRAASP 772 P V Y I GD +N F E + L + L R Y L+I+A Sbjct: 65 PQWAVRYRIISGDVANVFKTEEYVVGNFCFLRIRTKSSNTALLNREVRDSYTLIIQATEK 124 Query: 773 PLWNDV--RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYR 830 L + RV + + D ND P+ +D P +V A DAD+ ++ Sbjct: 125 TLELEALTRVVVHILDQNDLKPLFSPPSYRVTISEDMPLKSPICKVTATDADLGQNAEFY 184 Query: 831 ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEI 876 + + ++ T+G +T++ +LN ++V D + +I Sbjct: 185 YAFNTRSEMFAIHPTSGVVTVAGKLNVTWRGKHELQVLAVDRMRKI 230 >UniRef50_UPI0000F1D37C Cluster: PREDICTED: hypothetical protein; n=3; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 3267 Score = 336 bits (827), Expect = 4e-90 Identities = 265/859 (30%), Positives = 424/859 (49%), Gaps = 75/859 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD NDH PVF+ Y +V E G ++ + D D N+ V Y+ L Sbjct: 1611 VKVLDVNDHPPVFQQHIYNTTVIENRDPGEIIVQVTTVDLDSEVNSAVSYS--------L 1662 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P ++FRI+ +G + T LDRE + +T+ V+A D +P L Sbjct: 1663 LPGPGY-----------ELFRINSHTGHISTSVRLDREIQSTFTLRVQAEDSGTP---SL 1708 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SST T+ +++D+NDN PQFS+ + + E+++ VI ++A+D D G N I+Y+ Sbjct: 1709 SSTTTVLCSVLDENDNAPQFSQPDLHIVIPENLA---PGVIHIVQASDIDNGLNGTIQYS 1765 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I FSID+++G + + LD E+ +Y L+I A D G P S++ L I + D Sbjct: 1766 I---EDLECFSIDAVTGMIRTTRPLDREERSNYSLLITAADHGHPPLSSSALLHITLTDE 1822 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN+P F ++ S+SE +P+G I+ + A+D DEG N +T+++ +++ +GN Sbjct: 1823 NDNSPLFARKSYRASISEGLPVGTEILHLIAWDPDEGANGVVTFSL-EEENSGN----FH 1877 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDG-GDPPRSATATXXXXXXXXXXXXXXFMPG 369 +D +G + + LDRET++++ ATDG + PRS+ AT + Sbjct: 1878 VDGSTGVIKLTKPLDRETRSQHVFRAVATDGCSEGPRSSIATVTIQVEDINDNTPACVKE 1937 Query: 370 QYEVELAE-DEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 V ++ + P P+ +TA D D + F + +G G + + P Sbjct: 1938 PMRVSVSSVNTRPNRPIAKVTAQDPDLGDNGTVVFRLPEEDELFQV---DGSGAVRLKAP 1994 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV--FENAPYTASVFEDAPIGT 486 L + +L + A D G S T+ + + N+ P+ F Y +V E++ G+ Sbjct: 1995 LSNEVSGTKLLRIRAEDLGRPSLTSSCLL-LIQLNDEEPLLQFTEELYEVAVPENSKTGS 2053 Query: 487 TVLVVSATD--SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN--KLLDRE 542 V V A D SD G+ I Y++ S NEA F+INP TG IT N +LLD E Sbjct: 2054 WVANVVAHDQTSDEGM---IKYNIFSGNENEA-------FIINPVTGDITVNDQRLLDFE 2103 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 L V A +G + + V I++ D+NDN PVFKQ Y + E + T V Q Sbjct: 2104 VQRKVQLVVLAENGHQTAYA---RVAITLQDINDNAPVFKQSYYRTAVWEGQIHNTYVMQ 2160 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 V ATD+D G+NG+I Y + +FVID G++ TN LDRE V+++ L A D Sbjct: 2161 VLATDSDSGVNGQISYFI-MDGNHNNAFVIDSVRGILATNAVLDREIVSSYKLIIQAKDM 2219 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFES-DCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 G P + T V +++ D+ND+ P S + +T I+EN P+G + + A+D D P+A Sbjct: 2220 GKAPLTGTCTVRVQVVDVNDNSPTIPSMEAVT--IAENLPLGYIVTRVIANDVDLSPSA- 2276 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781 + I+ D S SF+++ G + T LDYE + Y L ++A+ + + Sbjct: 2277 TYRLIEKDDTSRSFAIDLYTGI----ITTTKILDYEE-QSVYTLKVQASDSVHQTEAELS 2331 Query: 782 ILVTDVNDNAPV--MKDFQIIFN--NYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNA 837 I V DVNDN+PV + +Q++ + D F V D+ ++ YR+LS + Sbjct: 2332 IQVLDVNDNSPVFSQESYQVLLSERTLADTFVVSVL--ATDKDSGKNGRVSYRLLS-SPV 2388 Query: 838 NLILLNETTGSMTLSPQLN 856 ++ GS+ + LN Sbjct: 2389 GGFYIDPDNGSVFTNKPLN 2407 Score = 322 bits (790), Expect = 1e-85 Identities = 266/896 (29%), Positives = 407/896 (45%), Gaps = 76/896 (8%) Query: 12 NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71 +VLD ND++P F + E + G + ++A+D D G N ++Y+IE + Sbjct: 1717 SVLDENDNAPQFSQPDLHIVIPENLAPGV-IHIVQASDIDNGLNGTIQYSIEDL------ 1769 Query: 72 PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131 + F ID +G + T LDRE+ + Y++L+ A D P LS Sbjct: 1770 ----------------ECFSIDAVTGMIRTTRPLDREERSNYSLLITAADHGHPP---LS 1810 Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191 S+A +H+ + D+NDN P F+ K+Y S+ E + V I + A D D GAN + +++ Sbjct: 1811 SSALLHITLTDENDNSPLFARKSYRASISEGLPVGTE--ILHLIAWDPDEGANGVVTFSL 1868 Query: 192 IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLINIRDV 250 N+ F +D +G + L K LD E + A DG S RS+ + I + D+ Sbjct: 1869 EEENSG-NFHVDGSTGVIKLTKPLDRETRSQHVFRAVATDGCSEGPRSSIATVTIQVEDI 1927 Query: 251 NDNAPRFYTSLFQESVSE-NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 NDN P + SVS N I +V A D D G N + + + ++D VD Sbjct: 1928 NDNTPACVKEPMRVSVSSVNTRPNRPIAKVTAQDPDLGDNGTVVFRLPEEDELFQVD--- 1984 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 SG V L E L + A D G P +++ F Sbjct: 1985 ----GSGAVRLKAPLSNEVSGTKLLRIRAEDLGRPSLTSSCLLLIQLNDEEPLLQ-FTEE 2039 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDN-RLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 YEV + E+ G+ V + A D D + Y I GN F I G + + Sbjct: 2040 LYEVAVPENSKTGSWVANVVAHDQTSDEGMIKYNIFSGNENEAFIINPVTGDITVNDQRL 2099 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 LDF+ +R+ L V A ++G ++ A V I + D N+ APVF+ + Y +V+E T V Sbjct: 2100 LDFEVQRKVQLVVLA-ENGHQTAYARVAITLQDINDNAPVFKQSYYRTAVWEGQIHNTYV 2158 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 + V ATDSD G+N QI+Y + +H+ FVI+ G + TN +LDRE +S Y Sbjct: 2159 MQVLATDSDSGVNGQISYFIMD-------GNHNNAFVIDSVRGILATNAVLDREIVSSYK 2211 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 L + A+D G L+ T V + VVDVNDN P + I E+ +G V++V A D Sbjct: 2212 LIIQAKDMGKAPLTGTCTVRVQVVDVNDNSPTI-PSMEAVTIAENLPLGYIVTRVIANDV 2270 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 D L+ Y L KD SF ID +G+I T K LD E + + LK A D ++ Sbjct: 2271 D--LSPSATYRLIEKDDTSRSFAIDLYTGIITTTKILDYEEQSVYTLKVQASDSVHQTEA 2328 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 + I++ D+ND+ PVF + +SE + T + + A D D G N V Y + Sbjct: 2329 E---LSIQVLDVNDNSPVFSQESYQVLLSERTLADTFVVSVLATDKDSGKNGRVSYRLL- 2384 Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVT 785 F ++ GS + T L+Y + L++ A P L+ V+I V Sbjct: 2385 SSPVGGFYIDPDNGS----VFTNKPLNYVANGNVLRLLVEARDSGDPNLFCVTSVDIEVA 2440 Query: 786 DVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK---LQYRILSGNNANLILL 842 D NDNAP N +D + A D D +D+ L+Y I+SGN+ L Sbjct: 2441 DFNDNAPFFTQNSYQINIPEDVSVGSTLITLLAEDKDYSDENTHLEYLIISGNDERRFCL 2500 Query: 843 ----------NETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLI 887 + T G + L L+ ++ V+VTD G+N + + +SV+++ Sbjct: 2501 EVVSIQAEPHSRTVGQLVLCDTLDRETTDAYSLTVTVTDRGINPLNSSTVVSVKVL 2556 Score = 316 bits (777), Expect = 4e-84 Identities = 271/898 (30%), Positives = 416/898 (46%), Gaps = 65/898 (7%) Query: 11 INVLDCNDHSPVFEMQQY--EASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68 I V D ND+ P F E +V + V+++ A D D G+N V++++ T + Sbjct: 1187 ITVTDVNDNRPQFTHMPSTKELNVWAVIPVNSVVISMFAKDLDAGENGTVKFSM---TDN 1243 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 L F ID SG + + RYT+ V ATD Sbjct: 1244 QLGH-----------------FSIDSLSGDVKVTSQFSSNPQMRYTLRVVATDNGL---F 1283 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 L TA +H+ + + F +V ED+ + +I + ++A ++ +R Sbjct: 1284 PLEETAVVHIQVYVLDQQKENFQSSFQHFTVLEDVGL--GTIIGSLGVSNAP---DTELR 1338 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y+I+ GN +QF I S SG++ + + LDYE + Y LV+RA+ P+ + T ++I Sbjct: 1339 YSIVEGNGSLQFGIKSSSGELYVAQHLDYEVTQRYFLVVRAE--AFPTFNVTVFAAVSIL 1396 Query: 249 DVNDNAPRFYTS--LFQESVSENVPIGYSIVRVQAYDADEGVN-AELTYTMTDKDYTGNV 305 DVND+ P F ++ + V E+V G + A D D ++ +EL Y++T Sbjct: 1397 DVNDHNPWFPSNGNIVIFGVHEDVSNGTVVYVFNARDGDGSLHYSELYYSLTFDPSPAIE 1456 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP---RSATATXXXXXXXXXXX 362 LP+ IDP +G V T+GQLDRE VTA+D P ++A+ Sbjct: 1457 GLPLHIDPHTGVVTTNGQLDRERTENIIFRVTASDSLKEPNERKNASIIAQMIVLDINDN 1516 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNGR 420 F+ + ED G V + A D DE H Y ++ GN + F + S Sbjct: 1517 SPTFVSMDIAC-VPEDTEVGLLVHHVMAKDKDEGRNGHVTYSVSSGNEKSYFHMEST--- 1572 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASV 478 G + + LD++ + ++L V A D+G S T + + + D N++ PVF+ Y +V Sbjct: 1573 GHLFLNSSLDYESQHVHILIVQARDNGVPSLSSTQTLTVKVLDVNDHPPVFQQHIYNTTV 1632 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 E+ G ++ V+ D D +N+ ++YSL E F IN TG I+T+ Sbjct: 1633 IENRDPGEIIVQVTTVDLDSEVNSAVSYSLLPGPGYEL-------FRINSHTGHISTSVR 1685 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 LDRE S + L V A D G PSLS TT V SV+D NDN P F Q I E+ G Sbjct: 1686 LDREIQSTFTLRVQAEDSGTPSLSSTTTVLCSVLDENDNAPQFSQPDLHIVIPENLAPGV 1745 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 + V A+D D GLNG I Y ++ D E F ID +G+IRT + LDRE + + L Sbjct: 1746 -IHIVQASDIDNGLNGTIQYSIE--DLE--CFSIDAVTGMIRTTRPLDREERSNYSLLIT 1800 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 A D G PP SS+ ++HI + D ND+ P+F ISE P+GT I + A DPDEG Sbjct: 1801 AADHGHPPLSSSALLHITLTDENDNSPLFARKSYRASISEGLPVGTEILHLIAWDPDEGA 1860 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP-PLWND 777 N VV +S++ ++S +F ++ G K L +D + S + S P + Sbjct: 1861 NGVVTFSLE-EENSGNFHVDGSTGVIK--LTKPLDRETRSQHVFRAVATDGCSEGPRSSI 1917 Query: 778 VRVEILVTDVNDNAPV-MKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNN 836 V I V D+NDN P +K+ + + + P P +V A D D+ D Sbjct: 1918 ATVTIQVEDINDNTPACVKEPMRVSVSSVNTRPNRPIAKVTAQDPDLGDNGTVVFRLPEE 1977 Query: 837 ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEEMLL 893 L + + +G++ L L+ V + + D G + + L ++L EE LL Sbjct: 1978 DELFQV-DGSGAVRLKAPLSNEVSGTKLLRIRAEDLGRPSLTSSCLLLIQLNDEEPLL 2034 Score = 312 bits (766), Expect = 9e-83 Identities = 258/890 (28%), Positives = 419/890 (47%), Gaps = 77/890 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 Q+ VLD ND+SP F A V E G V + A D+D G+N V Y++ Sbjct: 1507 QMIVLDINDNSPTFVSMDI-ACVPEDTEVGLLVHHVMAKDKDEGRNGHVTYSV------- 1558 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + F ++ +G L +SLD E + ++V+A D P Sbjct: 1559 ------------SSGNEKSYFHMES-TGHLFLNSSLDYESQHVHILIVQARDNGVP---S 1602 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LSST T+ V ++D ND+ P F + Y +V E+ +I ++ D D NSA+ Y Sbjct: 1603 LSSTQTLTVKVLDVNDHPPVFQQHIYNTTVIENRD--PGEIIVQVTTVDLDSEVNSAVSY 1660 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 +++ G F I+S +G +S LD E ++ L ++A+D G+PS S+TT +L ++ D Sbjct: 1661 SLLPGPGYELFRINSHTGHISTSVRLDREIQSTFTLRVQAEDSGTPSLSSTTTVLCSVLD 1720 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 NDNAP+F + EN+ G I VQA D D G+N + Y++ D + Sbjct: 1721 ENDNAPQFSQPDLHIVIPENLAPGV-IHIVQASDIDNGLNGTIQYSIEDLEC-------F 1772 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 +ID +G + T+ LDRE ++ Y LL+TA D G PP S++A F Sbjct: 1773 SIDAVTGMIRTTRPLDREERSNYSLLITAADHGHPPLSSSALLHITLTDENDNSPLFARK 1832 Query: 370 QYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 Y ++E P GT ++ L A D DE + + + + N+ G F + G+I + + Sbjct: 1833 SYRASISEGLPVGTEILHLIAWDPDEGANGVVTFSLEEENS-GNFHV--DGSTGVIKLTK 1889 Query: 428 PLDFKQERRYVLTVSATD---SGGRSDTAMVQINITDANNYAPVFENAPYTASVFE-DAP 483 PLD + ++V ATD G RS A V I + D N+ P P SV + Sbjct: 1890 PLDRETRSQHVFRAVATDGCSEGPRSSIATVTIQVEDINDNTPACVKEPMRVSVSSVNTR 1949 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 + V+A D D+G N + + L E D+ F ++ +GA+ L E Sbjct: 1950 PNRPIAKVTAQDPDLGDNGTVVFRLPEE---------DELFQVD-GSGAVRLKAPLSNEV 1999 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV--FKQQLYTANIMEDALVGTSVS 601 LL + A D G PSL+ + + ++ +ND EP+ F ++LY + E++ G+ V+ Sbjct: 2000 SGTKLLRIRAEDLGRPSLTSSC---LLLIQLNDEEPLLQFTEELYEVAVPENSKTGSWVA 2056 Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN--KALDRESVATHDLKAVA 659 V A D G I Y + + E +F+I+P +G I N + LD E L +A Sbjct: 2057 NVVAHD-QTSDEGMIKYNIFSGNENE-AFIINPVTGDITVNDQRLLDFEVQRKVQLVVLA 2114 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 +G Q++ V I ++DIND+ PVF+ + E T + ++ A D D G N Sbjct: 2115 ENG---HQTAYARVAITLQDINDNAPVFKQSYYRTAVWEGQIHNTYVMQVLATDSDSGVN 2171 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776 + Y I G+ +N+F +++ +G L T LD E Y+L+I+A PL Sbjct: 2172 GQISYFIMDGNHNNAFVIDSVRGI----LATNAVLDREIV-SSYKLIIQAKDMGKAPLTG 2226 Query: 777 DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDKLQYRIL-SG 834 V + V DVNDN+P + + + + P+G RV A D D++ YR++ Sbjct: 2227 TCTVRVQVVDVNDNSPTIPSMEAV--TIAENLPLGYIVTRVIANDVDLSPSATYRLIEKD 2284 Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884 + + ++ TG +T + L+ + T++V +D V++ +A + + V Sbjct: 2285 DTSRSFAIDLYTGIITTTKILDYEEQSVYTLKVQASDSVHQTEAELSIQV 2334 Score = 310 bits (761), Expect = 4e-82 Identities = 249/863 (28%), Positives = 400/863 (46%), Gaps = 63/863 (7%) Query: 11 INVLDCNDHSPVFEMQQYEA--SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68 +++LD NDH+P F V E S+GT V A D D + Y+ EL + Sbjct: 1393 VSILDVNDHNPWFPSNGNIVIFGVHEDVSNGTVVYVFNARDGD----GSLHYS-ELYYSL 1447 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 T +P A ID +G + T LDRE+ V A+D ++ Sbjct: 1448 TFDPSPAIEGL---------PLHIDPHTGVVTTNGQLDRERTENIIFRVTASDSLKEPNE 1498 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 R +++ + ++D NDN P F V ED V ++ + A D D G N + Sbjct: 1499 RKNASIIAQMIVLDINDNSPTFVSMD-IACVPEDTEV--GLLVHHVMAKDKDEGRNGHVT 1555 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y++ GN + F ++S +G + L +LDYE + L+++A+D G PS S+T L + + Sbjct: 1556 YSVSSGNEKSYFHMES-TGHLFLNSSLDYESQHVHILIVQARDNGVPSLSSTQTLTVKVL 1614 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 DVND+ P F ++ +V EN G IV+V D D VN+ ++Y++ +L Sbjct: 1615 DVNDHPPVFQQHIYNTTVIENRDPGEIIVQVTTVDLDSEVNSAVSYSLLPGP---GYEL- 1670 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 I+ +G + TS +LDRE Q+ + L V A D G P S+T T F Sbjct: 1671 FRINSHTGHISTSVRLDREIQSTFTLRVQAEDSGTPSLSSTTTVLCSVLDENDNAPQFSQ 1730 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 + + E+ PG + + A+D D + + Y I FSI + G+I Sbjct: 1731 PDLHIVIPENLAPGV-IHIVQASDIDNGLNGTIQYSIEDLEC---FSIDAVT--GMIRTT 1784 Query: 427 QPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 +PLD ++ Y L ++A D G S +A++ I +TD N+ +P+F Y AS+ E P+ Sbjct: 1785 RPLDREERSNYSLLITAADHGHPPLSSSALLHITLTDENDNSPLFARKSYRASISEGLPV 1844 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 GT +L + A D D G N +T+SL E S F ++ TG I K LDRET Sbjct: 1845 GTEILHLIAWDPDEGANGVVTFSLEEENSG--------NFHVDGSTGVIKLTKPLDRETR 1896 Query: 545 SGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEPV-FKQQLYTANIMEDALVGTSVSQ 602 S ++ A DG S V I V D+NDN P K+ + + + +++ Sbjct: 1897 SQHVFRAVATDGCSEGPRSSIATVTIQVEDINDNTPACVKEPMRVSVSSVNTRPNRPIAK 1956 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 V A D D+G NG + + L +D F +D SG +R L E T L+ A D Sbjct: 1957 VTAQDPDLGDNGTVVFRLPEEDE---LFQVD-GSGAVRLKAPLSNEVSGTKLLRIRAEDL 2012 Query: 663 GTPPQSSTVIVHIKIEDINDSPPV--FESDCLTFYISENSPIGTTIGEIRAHD--PDEGP 718 G P +S+ ++ I+ +ND P+ F + + ENS G+ + + AHD DEG Sbjct: 2013 GRPSLTSSCLLLIQ---LNDEEPLLQFTEELYEVAVPENSKTGSWVANVVAHDQTSDEG- 2068 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDV 778 ++ Y+I G+++ +F + G ++D + + +K +LV+ A + Sbjct: 2069 --MIKYNIFSGNENEAFIINPVTGDITVNDQRLLDFEVQ---RKVQLVVLAENGHQTAYA 2123 Query: 779 RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNN 836 RV I + D+NDNAPV K ++ +V A D+D V ++ Y I+ GN+ Sbjct: 2124 RVAITLQDINDNAPVFKQSYYRTAVWEGQIHNTYVMQVLATDSDSGVNGQISYFIMDGNH 2183 Query: 837 ANLILLNETTGSMTLSPQLNTNV 859 N +++ G + + L+ + Sbjct: 2184 NNAFVIDSVRGILATNAVLDREI 2206 Score = 301 bits (739), Expect = 2e-79 Identities = 234/789 (29%), Positives = 367/789 (46%), Gaps = 47/789 (5%) Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS 164 LDRE Y + V A+D P LSS T + + D NDN P F + Y S+DED+ Sbjct: 410 LDREIKDLYELTVTASDYGCPP---LSSVITFQIQVTDVNDNPPVFHQTIYEESIDEDVR 466 Query: 165 VTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR 224 V + ++KATD D+G +S I Y+I+ + F+ID G ++ LD+E+ R R Sbjct: 467 V--GTAVFRVKATDKDLGGDSEIIYSIVQSEQKCPFNIDPTLGVITTAAALDHERERELR 524 Query: 225 LVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA 284 ++ A DGGSPS S+T ++I++ DVNDN P F + +V E+ +G I++V A DA Sbjct: 525 FLVVASDGGSPSLSSTATVIIHVEDVNDNKPIFPQKFYNATVKEHTAVGTCILQVTAIDA 584 Query: 285 DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA-KYQLLVTATDGGD 343 D + Y + D +V I+ +G + S +D E + LL+ A D Sbjct: 585 DGAEFGSVQYFLYDGFSGKDVHPFFHINSVTGNICVSQDIDYEAGLLTFDLLIKAEDQVS 644 Query: 344 -----PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN- 397 S+ F PG+Y ++ PGT ++ + A+D D N Sbjct: 645 LSFVKDGFSSQTFVHIGIEDVNDNAPVFNPGKYVTSVSVHAQPGTELLNVYASDQDAGNY 704 Query: 398 -RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT--AM 454 ++ YE+ G++ F T G + ++ L + L+VSA D GG S A Sbjct: 705 GKITYELQPGDSATLF--TMDQSTGSVYLSSSLMQLRSSSVKLSVSARDGGGMSAAYPAN 762 Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 + +NI ++ +F+ A YT S+ EDAP+G++V +V A IT + S E+ + Sbjct: 763 ITVNILQSDQPPALFQKAQYTFSISEDAPVGSSVGLVQA----------ITPANSVEVVS 812 Query: 515 EAVAHHDQQ--FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572 ++ D Q F I+ QTG I T + LD E++S +L + G +P + + V +S+ Sbjct: 813 YVISSGDPQGFFSIDSQTGIINTAQPLDHESISYVILNIQFHTGTLP-IHSSAQVNVSIT 871 Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632 D+NDN PVF++ I GT + A D D G NGRIHY L PK F I Sbjct: 872 DINDNPPVFQKTSEHITISRTTPPGTPLFIAHAHDTDSGFNGRIHYMLHPKSH---LFTI 928 Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN--DSPPVFESD 690 P G + N + R+S + ++L +A D G P SST+ + I+++ D FE+ Sbjct: 929 HPNLGTLMLNGDVSRDSSSRYELSIIAEDEGHPSLSSTLGLVIEMDSSASVDDTLAFETL 988 Query: 691 CLTFYISENSPIGTTIGEIRAH---DPDEGPN----AVVHYSIKGGDDSNSFSLETRQGS 743 I E++P T + ++RAH G + +V+ YS+K F + G Sbjct: 989 VYQVEIGESAPKDTRMIQVRAHGNRSQHTGTSGKETSVITYSLKPLSGVPPFRIHPETGW 1048 Query: 744 DKAELVTMVDLDYES-PRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN 802 + LDYE+ P ++ + +A + + V ++V D NDNAPV F+ Sbjct: 1049 ----MFVSQSLDYETEPSYRFCVCAKAQNSKMEATATVVVMVQDENDNAPVFSRDVYFFS 1104 Query: 803 NYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKL 862 + P G G V A D D + + + +N TG + L+ Sbjct: 1105 VQEGPSPHGLIGTVKASDRDSLNNGVLSFILLTDGKYFSVNSRTGEIINLVALDREEQAQ 1164 Query: 863 ATMEVSVTD 871 + V VTD Sbjct: 1165 HVLRVMVTD 1173 Score = 294 bits (722), Expect = 2e-77 Identities = 237/782 (30%), Positives = 361/782 (46%), Gaps = 64/782 (8%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 + QI VLD ND+ PVF +Y A + E A+ T V + ATD D+G N +V Y I Sbjct: 219 LQAQITVLDENDNQPVFNQSEYHAVILENATLMTPVCQIFATDADLGSNGQVIYGINRRQ 278 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 +D + F I SG + LD E + Y ++V A D Sbjct: 279 SDP-----------------NEFFIIGSSSGIISVNKHLDYENESYYELIVTAWDSGIQP 321 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFS----EKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 SS + + +++ NDN P S + V E D +A+I +D D+G Sbjct: 322 E---SSNTFVSIKVLNVNDNPPNISVLFLNEAGAPEVSEGAGFED--YVARIAVSDPDLG 376 Query: 183 ANSAIRYAIIGGNTQMQF-SIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 I + GG+ S+D + + LD E Y L + A D G P S+ Sbjct: 377 DVKKIDVLLQGGDGMFSLRSMDDFLYVLCVDGPLDREIKDLYELTVTASDYGCPPLSSVI 436 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 I + DVNDN P F+ ++++ES+ E+V +G ++ RV+A D D G ++E+ Y++ + Sbjct: 437 TFQIQVTDVNDNPPVFHQTIYEESIDEDVRVGTAVFRVKATDKDLGGDSEIIYSIVQSEQ 496 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 P IDP G + T+ LD E + + + LV A+DGG P S+TAT Sbjct: 497 K----CPFNIDPTLGVITTAAALDHERERELRFLVVASDGGSPSLSSTATVIIHVEDVND 552 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEI----TGGNTRGRFSIT 415 F Y + E GT ++ +TA DAD E + Y + +G + F I Sbjct: 553 NKPIFPQKFYNATVKEHTAVGTCILQVTAIDADGAEFGSVQYFLYDGFSGKDVHPFFHIN 612 Query: 416 SQNGRGLITVAQPLDFKQER-RYVLTVSATDS-------GGRSDTAMVQINITDANNYAP 467 S G I V+Q +D++ + L + A D G S V I I D N+ AP Sbjct: 613 SVTGN--ICVSQDIDYEAGLLTFDLLIKAEDQVSLSFVKDGFSSQTFVHIGIEDVNDNAP 670 Query: 468 VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527 VF Y SV A GT +L V A+D D G +ITY L S F ++ Sbjct: 671 VFNPGKYVTSVSVHAQPGTELLNVYASDQDAGNYGKITYELQPGDSATL-------FTMD 723 Query: 528 PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT 587 TG++ + L + S L+V+ARDGG S + ++ ++++ + +F++ YT Sbjct: 724 QSTGSVYLSSSLMQLRSSSVKLSVSARDGGGMSAAYPANITVNILQSDQPPALFQKAQYT 783 Query: 588 ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647 +I EDA VG+SV V A + + Y + D +G F ID +G+I T + LD Sbjct: 784 FSISEDAPVGSSVGLVQAITPANSVEV-VSYVISSGD-PQGFFSIDSQTGIINTAQPLDH 841 Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 ES++ + + + GT P S+ V++ I DIND+PPVF+ IS +P GT + Sbjct: 842 ESIS-YVILNIQFHTGTLPIHSSAQVNVSITDINDNPPVFQKTSEHITISRTTPPGTPLF 900 Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 AHD D G N +HY + S+ F++ G+ L+ D+ +S +YEL I Sbjct: 901 IAHAHDTDSGFNGRIHYMLH--PKSHLFTIHPNLGT----LMLNGDVSRDS-SSRYELSI 953 Query: 768 RA 769 A Sbjct: 954 IA 955 Score = 273 bits (669), Expect = 5e-71 Identities = 226/799 (28%), Positives = 358/799 (44%), Gaps = 72/799 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D ND++PVF +Y SV A GT +L + A+DQD G ++ Y ++ Sbjct: 660 IGIEDVNDNAPVFNPGKYVTSVSVHAQPGTELLNVYASDQDAGNYGKITYELQ------- 712 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P D+ +F +D +G++ +SL + + + + V A D + Sbjct: 713 -PGDSAT-----------LFTMDQSTGSVYLSSSLMQLRSSSVKLSVSARDGGGMSA--- 757 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA--IR 188 + A I VNI+ + F + YT S+ ED PV + + A ANS + Sbjct: 758 AYPANITVNILQSDQPPALFQKAQYTFSISEDA-----PVGSSVGLVQAITPANSVEVVS 812 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y I G+ Q FSIDS +G ++ + LD+E + L I+ G P S+ Q+ ++I Sbjct: 813 YVISSGDPQGFFSIDSQTGIINTAQPLDHESISYVILNIQFHTGTLPIHSSA-QVNVSIT 871 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D+NDN P F + ++S P G + A+D D G N + Y + K + Sbjct: 872 DINDNPPVFQKTSEHITISRTTPPGTPLFIAHAHDTDSGFNGRIHYMLHPKSHL------ 925 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA--TXXXXXXXXXXXXXXF 366 TI P G + +G + R++ ++Y+L + A D G P S+T F Sbjct: 926 FTIHPNLGTLMLNGDVSRDSSSRYELSIIAEDEGHPSLSSTLGLVIEMDSSASVDDTLAF 985 Query: 367 MPGQYEVELAEDEPPGTPVVTL---------TATDADEDNRLHYEITGGNTRGRFSITSQ 417 Y+VE+ E P T ++ + T T E + + Y + + F I + Sbjct: 986 ETLVYQVEIGESAPKDTRMIQVRAHGNRSQHTGTSGKETSVITYSLKPLSGVPPFRIHPE 1045 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSD-TAMVQINITDANNYAPVFENAPYTA 476 G + V+Q LD++ E Y V A + + TA V + + D N+ APVF Y Sbjct: 1046 TG--WMFVSQSLDYETEPSYRFCVCAKAQNSKMEATATVVVMVQDENDNAPVFSRDVYFF 1103 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 SV E + V A+D D N +++ L ++ + F +N +TG I Sbjct: 1104 SVQEGPSPHGLIGTVKASDRDSLNNGVLSFILLTD---------GKYFSVNSRTGEIINL 1154 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT--ANIMEDA 594 LDRE + ++L V D G P L+ TT + I+V DVNDN P F T N+ Sbjct: 1155 VALDREEQAQHVLRVMVTDQGRPRLNTTTTIHITVTDVNDNRPQFTHMPSTKELNVWAVI 1214 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654 V + V + A D D G NG + + + D + G F ID SG ++ + Sbjct: 1215 PVNSVVISMFAKDLDAGENGTVKFSM--TDNQLGHFSIDSLSGDVKVTSQFSSNPQMRYT 1272 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 L+ VA D G P T +VHI++ ++ F+S F + E+ +GT IG + Sbjct: 1273 LRVVATDNGLFPLEETAVVHIQVYVLDQQKENFQSSFQHFTVLEDVGLGTIIGSLGV--- 1329 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL 774 P+ + YSI G+ S F +++ G EL LDYE ++Y LV+RA + P Sbjct: 1330 SNAPDTELRYSIVEGNGSLQFGIKSSSG----ELYVAQHLDYE-VTQRYFLVVRAEAFPT 1384 Query: 775 WN-DVRVEILVTDVNDNAP 792 +N V + + DVND+ P Sbjct: 1385 FNVTVFAAVSILDVNDHNP 1403 Score = 271 bits (665), Expect = 2e-70 Identities = 228/785 (29%), Positives = 355/785 (45%), Gaps = 49/785 (6%) Query: 134 ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG 193 A + + + D NDN P F + Y +V E N + ++ ATD+D G N I Y I+ Sbjct: 2123 ARVAITLQDINDNAPVFKQSYYRTAVWE--GQIHNTYVMQVLATDSDSGVNGQISYFIMD 2180 Query: 194 GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDN 253 GN F IDS+ G ++ LD E V SY+L+I+A+D G + T + + + DVNDN Sbjct: 2181 GNHNNAFVIDSVRGILATNAVLDREIVSSYKLIIQAKDMGKAPLTGTCTVRVQVVDVNDN 2240 Query: 254 APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313 +P S+ +++EN+P+GY + RV A D D +A TY + +KD T ID Sbjct: 2241 SPTI-PSMEAVTIAENLPLGYIVTRVIANDVDLSPSA--TYRLIEKDDTSR---SFAIDL 2294 Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373 +G + T+ LD E Q+ Y L V A+D A F Y+V Sbjct: 2295 YTGIITTTKILDYEEQSVYTLKVQASDS---VHQTEAELSIQVLDVNDNSPVFSQESYQV 2351 Query: 374 ELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431 L+E T VV++ ATD D ++ R+ Y + G F I NG + +PL++ Sbjct: 2352 LLSERTLADTFVVSVLATDKDSGKNGRVSYRLLSSPVGG-FYIDPDNGS--VFTNKPLNY 2408 Query: 432 KQERRYV-LTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 + L V A DSG + V I + D N+ AP F Y ++ ED +G+T+ Sbjct: 2409 VANGNVLRLLVEARDSGDPNLFCVTSVDIEVADFNDNAPFFTQNSYQINIPEDVSVGSTL 2468 Query: 489 LVVSATDSDVGI-NAQITYSLSSEISNEAVAHHDQQFVINPQT---GAITTNKLLDRETM 544 + + A D D N + Y + S P + G + LDRET Sbjct: 2469 ITLLAEDKDYSDENTHLEYLIISGNDERRFCLEVVSIQAEPHSRTVGQLVLCDTLDRETT 2528 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 Y LTVT D G+ L+ +T V + V+D+NDN P F Y A + E++ VG + QV Sbjct: 2529 DAYSLTVTVTDRGINPLNSSTVVSVKVLDINDNAPAFSSPEYHAQVSENSPVGLVLVQVS 2588 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 A D D+G NG I Y + +G +D ++GVI+ N LD E L A D GT Sbjct: 2589 AYDPDLGANGTITYNI-ISGNSKGLITVDSSTGVIKVNGTLDYEEDTKLTLTVQASDWGT 2647 Query: 665 PPQS--STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 S +V+I + D ND+ P F +SEN P T + + A D D G ++ Sbjct: 2648 SDDKKVSFAVVYILVLDENDNSPFFMFPTYNCSVSENLPAFTPVCTVHAVDEDAGTFGLL 2707 Query: 723 HYSIKG----GDDSNSFSLETRQGSD--KAELVTMVDLDYESPRKKYELVIRAASPPLWN 776 YSI DS++ + G D ++ T DYE R +V Sbjct: 2708 SYSIVTPCFVDYDSSNPDKKEAFGIDPLTGDIHTKQTFDYEGDRNFCFVVEARDKGDQVA 2767 Query: 777 DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-----FGRVPAYDAD--VTDKLQY 829 +RV I + +++ +P+ N Y P P G + A D D + ++Y Sbjct: 2768 TLRVRIEIEGIDEFSPIFTQ-----NVYHFSLPANPKVGQSIGYLMAMDHDGGLDGLVEY 2822 Query: 830 RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889 ++S ++ +N+T G + +S N+ + + + T+ + + + +L R T Sbjct: 2823 SLVS--PSSFFNVNKTNGCLFVS---NSVYQRQSPISNETTEDLIVLASSPKLDSRSSTC 2877 Query: 890 EMLLN 894 +++N Sbjct: 2878 HVIVN 2882 Score = 257 bits (629), Expect = 4e-66 Identities = 242/828 (29%), Positives = 364/828 (43%), Gaps = 60/828 (7%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F IDG +G + T LDRE+ +Y AT + + + + D NDN+P Sbjct: 72 FEIDGDTGIISTAVVLDRERTDKYE-FAAATLTGEVIK--------VSIQVTDVNDNFPI 122 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG-- 207 F K ++V E +S + A D D G Y I G + F ++ S Sbjct: 123 FPVKIIHLNVSE-LSPPGTRFELE-GAQDKDEGDYGTQGYRITDGEMRELFKVEIRSNGV 180 Query: 208 -----DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLF 262 D+ L LD E Y I A DGG P ++ Q I + D NDN P F S + Sbjct: 181 GMFNLDLVLQTRLDREIADFYNFTIEAFDGGVPPKTGQLQAQITVLDENDNQPVFNQSEY 240 Query: 263 QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322 + EN + + ++ A DAD G N ++ Y + + N I SG + + Sbjct: 241 HAVILENATLMTPVCQIFATDADLGSNGQVIYGINRRQSDPNEFF--IIGSSSGIISVNK 298 Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX----XXXFMPGQYEVELAED 378 LD E ++ Y+L+VTA D G P S+ F+ E++E Sbjct: 299 HLDYENESYYELIVTAWDSGIQPESSNTFVSIKVLNVNDNPPNISVLFLNEAGAPEVSEG 358 Query: 379 EPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG-RGLITVAQPLDFKQER 435 V + +D D + ++ + GG+ G FS+ S + ++ V PLD + + Sbjct: 359 AGFEDYVARIAVSDPDLGDVKKIDVLLQGGD--GMFSLRSMDDFLYVLCVDGPLDREIKD 416 Query: 436 RYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 Y LTV+A+D G S QI +TD N+ PVF Y S+ ED +GT V V A Sbjct: 417 LYELTVTASDYGCPPLSSVITFQIQVTDVNDNPPVFHQTIYEESIDEDVRVGTAVFRVKA 476 Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553 TD D+G +++I YS+ + +E F I+P G ITT LD E V A Sbjct: 477 TDKDLGGDSEIIYSI---VQSEQKC----PFNIDPTLGVITTAAALDHERERELRFLVVA 529 Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613 DGG PSLS T V I V DVNDN+P+F Q+ Y A + E VGT + QV A DAD Sbjct: 530 SDGGSPSLSSTATVIIHVEDVNDNKPIFPQKFYNATVKEHTAVGTCILQVTAIDADGAEF 589 Query: 614 GRIHYEL----DPKDREEGSFVIDPASGVIRTNKALDRES-VATHDL--KA---VAIDGG 663 G + Y L KD F I+ +G I ++ +D E+ + T DL KA V++ Sbjct: 590 GSVQYFLYDGFSGKD-VHPFFHINSVTGNICVSQDIDYEAGLLTFDLLIKAEDQVSLSFV 648 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 SS VHI IED+ND+ PVF +S ++ GT + + A D D G + Sbjct: 649 KDGFSSQTFVHIGIEDVNDNAPVFNPGKYVTSVSVHAQPGTELLNVYASDQDAGNYGKIT 708 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR---AASPPLWNDVRV 780 Y ++ GD + F+++ GS ++ + S K + R S ++ V Sbjct: 709 YELQPGDSATLFTMDQSTGS---VYLSSSLMQLRSSSVKLSVSARDGGGMSAAYPANITV 765 Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAY-DADVTDKLQYRILSGNNAN 838 IL +D + + Q F+ +D PVG G V A A+ + + Y I SG+ Sbjct: 766 NILQSD--QPPALFQKAQYTFSISEDA-PVGSSVGLVQAITPANSVEVVSYVISSGDPQG 822 Query: 839 LILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886 ++ TG + + L+ + + G I + Q++V + Sbjct: 823 FFSIDSQTGIINTAQPLDHESISYVILNIQFHTGTLPIHSSAQVNVSI 870 Score = 227 bits (554), Expect = 4e-57 Identities = 187/648 (28%), Positives = 298/648 (45%), Gaps = 40/648 (6%) Query: 52 IGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA 111 I +N + Y + V A+ ++ + F ID +G + T LD E+ + Sbjct: 2252 IAENLPLGYIVTRVIANDVDLSPSATYRLIEKDDTSRSFAIDLYTGIITTTKILDYEEQS 2311 Query: 112 RYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVI 171 YT+ V+A+D LS + ++D NDN P FS+++Y V + E ++ D V+ Sbjct: 2312 VYTLKVQASDSVHQTEAELS------IQVLDVNDNSPVFSQESYQVLLSER-TLADTFVV 2364 Query: 172 AKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDY-EQVRSYRLVIRAQ 230 + + ATD D G N + Y ++ F ID +G V K L+Y RL++ A+ Sbjct: 2365 S-VLATDKDSGKNGRVSYRLLSSPVG-GFYIDPDNGSVFTNKPLNYVANGNVLRLLVEAR 2422 Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVN 289 D G P+ T + I + D NDNAP F + +Q ++ E+V +G +++ + A D D N Sbjct: 2423 DSGDPNLFCVTSVDIEVADFNDNAPFFTQNSYQINIPEDVSVGSTLITLLAEDKDYSDEN 2482 Query: 290 AELTYTMTDKDYTGNVDL---PITIDPRS---GWVYTSGQLDRETQAKYQLLVTATDGGD 343 L Y + + L I +P S G + LDRET Y L VT TD G Sbjct: 2483 THLEYLIISGNDERRFCLEVVSIQAEPHSRTVGQLVLCDTLDRETTDAYSLTVTVTDRGI 2542 Query: 344 PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHY 401 P +++ F +Y +++E+ P G +V ++A D D + + Y Sbjct: 2543 NPLNSSTVVSVKVLDINDNAPAFSSPEYHAQVSENSPVGLVLVQVSAYDPDLGANGTITY 2602 Query: 402 EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT----AMVQI 457 I GN++G IT + G+I V LD++++ + LTV A+D G D A+V I Sbjct: 2603 NIISGNSKG--LITVDSSTGVIKVNGTLDYEEDTKLTLTVQASDWGTSDDKKVSFAVVYI 2660 Query: 458 NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI---SN 514 + D N+ +P F Y SV E+ P T V V A D D G ++YS+ + + Sbjct: 2661 LVLDENDNSPFFMFPTYNCSVSENLPAFTPVCTVHAVDEDAGTFGLLSYSIVTPCFVDYD 2720 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 + + F I+P TG I T + D E + V ARD G T V I + + Sbjct: 2721 SSNPDKKEAFGIDPLTGDIHTKQTFDYEGDRNFCFVVEARDKG--DQVATLRVRIEIEGI 2778 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634 ++ P+F Q +Y ++ + VG S+ + A D D GL+G + Y L F ++ Sbjct: 2779 DEFSPIFTQNVYHFSLPANPKVGQSIGYLMAMDHDGGLDGLVEYSL---VSPSSFFNVNK 2835 Query: 635 ASG-VIRTNKALDRES----VATHDLKAVAIDGGTPPQSST--VIVHI 675 +G + +N R+S T DL +A +SST VIV+I Sbjct: 2836 TNGCLFVSNSVYQRQSPISNETTEDLIVLASSPKLDSRSSTCHVIVNI 2883 Score = 158 bits (383), Expect = 2e-36 Identities = 134/491 (27%), Positives = 219/491 (44%), Gaps = 35/491 (7%) Query: 5 FCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIG-KNAEVEYTI 62 FC+ I V D ND++P F Y+ ++ E S G+T++TL A D+D +N +EY I Sbjct: 2430 FCVTSVDIEVADFNDNAPFFTQNSYQINIPEDVSVGSTLITLLAEDKDYSDENTHLEYLI 2489 Query: 63 ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122 ++ + ++ + R G+ L+ +LDRE Y++ V TD+ Sbjct: 2490 --ISGN----DERRFCLEVVSIQAEPHSRTVGQ---LVLCDTLDRETTDAYSLTVTVTDR 2540 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 + L+S+ + V ++D NDN P FS Y V E+ V V+ ++ A D D+G Sbjct: 2541 GI---NPLNSSTVVSVKVLDINDNAPAFSSPEYHAQVSENSPV--GLVLVQVSAYDPDLG 2595 Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS--PSRSNT 240 AN I Y II GN++ ++DS +G + + TLDYE+ L ++A D G+ + + Sbjct: 2596 ANGTITYNIISGNSKGLITVDSSTGVIKVNGTLDYEEDTKLTLTVQASDWGTSDDKKVSF 2655 Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK- 299 + I + D NDN+P F + SVSEN+P + V A D D G L+Y++ Sbjct: 2656 AVVYILVLDENDNSPFFMFPTYNCSVSENLPAFTPVCTVHAVDEDAGTFGLLSYSIVTPC 2715 Query: 300 --DY-TGNVDL--PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354 DY + N D IDP +G ++T D E + +V A D GD + AT Sbjct: 2716 FVDYDSSNPDKKEAFGIDPLTGDIHTKQTFDYEGDRNFCFVVEARDKGD--QVATLRVRI 2773 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRF 412 F Y L + G + L A D D D + Y + ++ F Sbjct: 2774 EIEGIDEFSPIFTQNVYHFSLPANPKVGQSIGYLMAMDHDGGLDGLVEYSLVSPSS--FF 2831 Query: 413 SITSQNG-----RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAP 467 ++ NG + P+ + ++ S+ RS T V +NI+ Sbjct: 2832 NVNKTNGCLFVSNSVYQRQSPISNETTEDLIVLASSPKLDSRSSTCHVIVNISSTTKALA 2891 Query: 468 VFENAPYTASV 478 + + +TA++ Sbjct: 2892 SADFSVHTATL 2902 Score = 107 bits (258), Expect = 3e-21 Identities = 97/308 (31%), Positives = 134/308 (43%), Gaps = 21/308 (6%) Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554 D G+ A+ T S IS + + F I+ TG I+T +LDRE Y Sbjct: 44 DIRAGLPAK-TQSSGFFISESRDSEVFRDFEIDGDTGIISTAVVLDRERTDKYEFAAATL 102 Query: 555 DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614 G + V I V DVNDN P+F ++ N+ E + GT GA D D G G Sbjct: 103 TG------EVIKVSIQVTDVNDNFPIFPVKIIHLNVSELSPPGTRFELEGAQDKDEGDYG 156 Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTN------KALDRESVATHDLKAVAIDGGTPPQS 668 Y + + E V ++GV N LDRE ++ A DGG PP++ Sbjct: 157 TQGYRITDGEMRELFKVEIRSNGVGMFNLDLVLQTRLDREIADFYNFTIEAFDGGVPPKT 216 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-K 727 + I + D ND+ PVF I EN+ + T + +I A D D G N V Y I + Sbjct: 217 GQLQAQITVLDENDNQPVFNQSEYHAVILENATLMTPVCQIFATDADLGSNGQVIYGINR 276 Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILV 784 D N F + GS + LDYE+ YEL++ A P ++ V I V Sbjct: 277 RQSDPNEFFI---IGSSSGIISVNKHLDYEN-ESYYELIVTAWDSGIQPESSNTFVSIKV 332 Query: 785 TDVNDNAP 792 +VNDN P Sbjct: 333 LNVNDNPP 340 Score = 44.4 bits (100), Expect = 0.046 Identities = 49/151 (32%), Positives = 65/151 (43%), Gaps = 11/151 (7%) Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751 L+ + E P T +G+IRA P + ++ + I DS F + D + T Sbjct: 28 LSLSVEEGLPAKTIVGDIRAGLPAKTQSS--GFFISESRDSEVFR-DFEIDGDTGIISTA 84 Query: 752 VDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811 V LD E KYE AA+ ++V I VTDVNDN P+ +II N + P G Sbjct: 85 VVLDRER-TDKYEF---AAATLTGEVIKVSIQVTDVNDNFPIF-PVKIIHLNVSELSPPG 139 Query: 812 P-FGRVPAYDADVTD--KLQYRILSGNNANL 839 F A D D D YRI G L Sbjct: 140 TRFELEGAQDKDEGDYGTQGYRITDGEMREL 170 >UniRef50_Q4SRZ9 Cluster: Chromosome 18 SCAF14485, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 18 SCAF14485, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 3280 Score = 334 bits (820), Expect = 3e-89 Identities = 261/869 (30%), Positives = 412/869 (47%), Gaps = 59/869 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D ND PVF Y ASV E G V + ATD D +NA V Y+ L Sbjct: 1645 VEVADVNDQPPVFSQSVYNASVAENKDPGEPVARVSATDGDSEENAVVWYS--------L 1696 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P ++F I+ +G + T + LDRE+ +T+ V+A D L Sbjct: 1697 LPGPGY-----------ELFSINPDTGLITTASYLDREQQHGFTLRVQARDSGPRP---L 1742 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+TAT+ +++DDNDN P F + ++ +S+ E++ I +A+D D+G N I Y+ Sbjct: 1743 SATATVLCSVLDDNDNPPAFMQSSFRISLPENLPPG---AIHTAQASDPDLGENGTILYS 1799 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I+G + F+++S SG VS K LD E+ ++Y L I+A+D G S++TQL + + D Sbjct: 1800 IVGEDCAGCFTVNSRSGVVSTTKVLDREEKQNYTLTIQARDYGPTPLSSSTQLQLVLLDR 1859 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDNAP F +Q SVSE +P G ++RV A+D DEG N +TY++T+ G + Sbjct: 1860 NDNAPSFSRKSYQASVSEGLPPGAEVLRVSAFDPDEGPNGRVTYSLTEDSSQG----AFS 1915 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDG-GDPPRSATATXXXXXXXXXXXXXXFMPG 369 +D +G + T+G LDRE++A+Y L ATDG P ++ A+ Sbjct: 1916 VDSLTGVIRTTGPLDRESRAQYTLRAVATDGCTQGPLTSVASVTVQVEDVNDNVPICDQN 1975 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 ++ P V T+TA D+D+ + + F I + G + Sbjct: 1976 PVNAWVSARTLPNQIVATVTAEDSDQGENGTIQFALSDEENLFDINRETGEISVRRRVRA 2035 Query: 430 DFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 F R+ + VS + T +V I++ N F N Y A++ E++ G V Sbjct: 2036 GF-SGRKLEVMVSDRGRPVLTSTCLVFIHL-KGENEGLQFTNKVYNATIKENSGAGILVT 2093 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK--LLDRETMSGY 547 V A+ + G + Y++ S NE + F IN TG I K LD E +S + Sbjct: 2094 KVEAS-GEAGSRQSVVYTIFS--GNE-----NSLFSINHHTGEIRVQKDYALDFE-LSPH 2144 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 + V D G+ + V I ++DVNDN P F++ Y + E T V Q+ A+D Sbjct: 2145 IHLVVLADNGLQTTH--CRVSIHLLDVNDNAPRFERSSYRTAVWEGQAHNTYVMQMFASD 2202 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 AD G+NG+I Y + D E +F++D G++ T+ LDRE ++ L A D G PP Sbjct: 2203 ADSGINGQIEYSIVSGDPNE-AFILDSVRGILATSIPLDREITPSYKLVLQAADQGDPPL 2261 Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 SST V +++ D+ND+ P I+EN P G T+ ++ A+D D ++ + YS+ Sbjct: 2262 SSTATVRVQVVDVNDNSPAI-PHMEPVVIAENRPAGHTVTQVTANDVD--LSSTIRYSLS 2318 Query: 728 GGDDSNS-FSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRAASPPLWNDVRVEILVT 785 G S F++ G +V++ LDYE + +Y L + A+ V++ V Sbjct: 2319 GNSSLGSPFAINQYTG-----VVSLTRALDYEE-QAEYTLTVLASDSLHQTSGEVKVQVL 2372 Query: 786 DVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLN 843 D+NDNAPV + +Q+ + + D+ ++ YR+LS + Sbjct: 2373 DLNDNAPVFSEDSYQVDLSELATADTLVLSVSATDRDSGPNGEITYRLLSSPLQGFYIQA 2432 Query: 844 ETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 ++ T P T L + V DG Sbjct: 2433 DSGAIFTNKPIKATANGNLIHLLVEAKDG 2461 Score = 327 bits (803), Expect = 3e-87 Identities = 271/894 (30%), Positives = 421/894 (47%), Gaps = 56/894 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI------E 63 Q+ +LD ND+ PVF + V E A G+ + A D D G+N V YTI Sbjct: 1515 QVFLLDVNDNRPVF-ISAVSVQVMEDAEVGSLLHRFVAKDGDEGENGLVSYTILTGNKKG 1573 Query: 64 LVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQA 123 + T + + V ++ + G L ++LD E + ++V+A D Sbjct: 1574 MFTLEGNTGKMPLFCLHPLCFSVLNLSCLHFSPGLLFLASALDYESQRLHRLIVEAVDHG 1633 Query: 124 SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183 P LSST T V + D ND P FS+ Y SV E+ + PV A++ ATD D Sbjct: 1634 LP---SLSSTQTFTVEVADVNDQPPVFSQSVYNASVAENKDPGE-PV-ARVSATDGDSEE 1688 Query: 184 NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 N+ + Y+++ G FSI+ +G ++ LD EQ + L ++A+D G S T + Sbjct: 1689 NAVVWYSLLPGPGYELFSINPDTGLITTASYLDREQQHGFTLRVQARDSGPRPLSATATV 1748 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 L ++ D NDN P F S F+ S+ EN+P G +I QA D D G N + Y++ +D G Sbjct: 1749 LCSVLDDNDNPPAFMQSSFRISLPENLPPG-AIHTAQASDPDLGENGTILYSIVGEDCAG 1807 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 T++ RSG V T+ LDRE + Y L + A D G P S++ Sbjct: 1808 ----CFTVNSRSGVVSTTKVLDREEKQNYTLTIQARDYGPTPLSSSTQLQLVLLDRNDNA 1863 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRG 421 F Y+ ++E PPG V+ ++A D DE + R+ Y +T +++G FS+ S G Sbjct: 1864 PSFSRKSYQASVSEGLPPGAEVLRVSAFDPDEGPNGRVTYSLTEDSSQGAFSVDSLT--G 1921 Query: 422 LITVAQPLDFKQERRYVLTVSATD---SGGRSDTAMVQINITDANNYAPVFENAPYTASV 478 +I PLD + +Y L ATD G + A V + + D N+ P+ + P A V Sbjct: 1922 VIRTTGPLDRESRAQYTLRAVATDGCTQGPLTSVASVTVQVEDVNDNVPICDQNPVNAWV 1981 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 V V+A DSD G N I ++LS E + F IN +TG I+ + Sbjct: 1982 SARTLPNQIVATVTAEDSDQGENGTIQFALSDE---------ENLFDINRETGEISVRRR 2032 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 + R SG L V D G P L+ T V I + N+ F ++Y A I E++ G Sbjct: 2033 V-RAGFSGRKLEVMVSDRGRPVLTSTCLVFIHLKGENEGLQ-FTNKVYNATIKENSGAGI 2090 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK--ALDRESVATHDLK 656 V++V A+ + G + Y + E F I+ +G IR K ALD E ++ H Sbjct: 2091 LVTKVEAS-GEAGSRQSVVYTIF-SGNENSLFSINHHTGEIRVQKDYALDFE-LSPHIHL 2147 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 V D G V +H+ D+ND+ P FE + E T + ++ A D D Sbjct: 2148 VVLADNGLQTTHCRVSIHLL--DVNDNAPRFERSSYRTAVWEGQAHNTYVMQMFASDADS 2205 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPP 773 G N + YSI GD + +F L++ +G L T + LD E Y+LV++AA PP Sbjct: 2206 GINGQIEYSIVSGDPNEAFILDSVRGI----LATSIPLDREI-TPSYKLVLQAADQGDPP 2260 Query: 774 LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRIL 832 L + V + V DVNDN+P + + + + P G +V A D D++ ++Y L Sbjct: 2261 LSSTATVRVQVVDVNDNSPAIPHMEPVV--IAENRPAGHTVTQVTANDVDLSSTIRYS-L 2317 Query: 833 SGNNA--NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884 SGN++ + +N+ TG ++L+ L+ T+ V +D +++ +++ V Sbjct: 2318 SGNSSLGSPFAINQYTGVVSLTRALDYEEQAEYTLTVLASDSLHQTSGEVKVQV 2371 Score = 317 bits (779), Expect = 2e-84 Identities = 242/804 (30%), Positives = 397/804 (49%), Gaps = 77/804 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D ND+ P+ + A V V T+ A D D G+N +++ L Sbjct: 1960 VQVEDVNDNVPICDQNPVNAWVSARTLPNQIVATVTAEDSDQGENGTIQFA--------L 2011 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + E+ ++F I+ +G + R + R + + V +D+ PV L Sbjct: 2012 SDEE-------------NLFDINRETGEISVRRRV-RAGFSGRKLEVMVSDRGRPV---L 2054 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +ST + +++ +N+ QF+ K Y ++ E+ ++ K++A+ + G+ ++ Y Sbjct: 2055 TSTCLVFIHLKGENEGL-QFTNKVYNATIKENSGA--GILVTKVEAS-GEAGSRQSVVYT 2110 Query: 191 IIGGNTQMQFSIDSLSGDVSLVK--TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 I GN FSI+ +G++ + K LD+E LV+ A +G ++ ++ I++ Sbjct: 2111 IFSGNENSLFSINHHTGEIRVQKDYALDFELSPHIHLVVLADNG---LQTTHCRVSIHLL 2167 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 DVNDNAPRF S ++ +V E ++++ A DAD G+N ++ Y++ +G+ + Sbjct: 2168 DVNDNAPRFERSSYRTAVWEGQAHNTYVMQMFASDADSGINGQIEYSIV----SGDPNEA 2223 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 +D G + TS LDRE Y+L++ A D GDPP S+TAT +P Sbjct: 2224 FILDSVRGILATSIPLDREITPSYKLVLQAADQGDPPLSSTATVRVQVVDVNDNSPA-IP 2282 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGR-FSITSQNGRGLITVAQ 427 V +AE+ P G V +TA D D + + Y ++G ++ G F+I G ++++ + Sbjct: 2283 HMEPVVIAENRPAGHTVTQVTANDVDLSSTIRYSLSGNSSLGSPFAINQYTG--VVSLTR 2340 Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 LD++++ Y LTV A+DS ++ + V++ + D N+ APVF Y + E A T Sbjct: 2341 ALDYEEQAEYTLTVLASDSLHQT-SGEVKVQVLDLNDNAPVFSEDSYQVDLSELATADTL 2399 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 VL VSATD D G N +ITY L S Q F I +GAI TNK + + T +G Sbjct: 2400 VLSVSATDRDSGPNGEITYRLLSSPL--------QGFYIQADSGAIFTNKPI-KATANGN 2450 Query: 548 L--LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 L L V A+DGG P+LS V++ ++D ND+ P F Q++Y+ I ED ++ + A Sbjct: 2451 LIHLLVEAKDGGDPALSSVASVDVQILDTNDHVPTFHQEVYSLTIPEDTPTDATLLTLSA 2510 Query: 606 TDADVG-LNGRIHYELDPKDREEGSFVID----PAS------GVIRTNKALDRESVATHD 654 D D N + Y + + EE F ++ P G + ALDRE+ ++ Sbjct: 2511 EDQDWSPANTHLDYAIT-QGNEERRFCLEVRLVPIENQWRNVGKLVLCNALDRETTDSYV 2569 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 L D G PP +S+ +V + + D ND+ PVF S +SE+SP GT + ++ A DP Sbjct: 2570 LTVSVSDRGDPPLNSSAVVMLTVADRNDNAPVFSSTEYHAQVSESSPRGTRLVQVSARDP 2629 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL 774 D G N++V + I G+ + L+ G L LDYE KY L +RA+ Sbjct: 2630 DLGANSLVRFDIISGNSKGHYKLDPESGL----LAVNQSLDYEQD-PKYILTVRASDGGE 2684 Query: 775 WNDVR------VEILVTDVNDNAP 792 +++ V I V D NDN+P Sbjct: 2685 FSEKHQVAFAVVFITVLDENDNSP 2708 Score = 312 bits (766), Expect = 9e-83 Identities = 263/882 (29%), Positives = 402/882 (45%), Gaps = 50/882 (5%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 I +I V D NDHSPVF + + E + G+ A D+D E E+ + Sbjct: 102 IKVRIEVKDVNDHSPVFPSEGLNLEISEVSPPGSRFKLEGAKDED-----EDEFGTQGYR 156 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 E+ Q + S L+ + LDRE+ Y++ ++A D P Sbjct: 157 IRESEMEERFHLDHHRSGSGQHL------SLDLVLMSRLDREEQDFYSLTIEAFDGGVPP 210 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 + T + ++++D+NDN P F++ Y SV ED + +PV ++ ATD D+G N Sbjct: 211 R---TGTLQLRIHVLDENDNPPVFNQTEYHASVPEDAPLM-SPV-CQVHATDLDLGDNGR 265 Query: 187 IRYAIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 I Y I + FSI+ SG V + K LDYE + L++ A D G+ ++T + Sbjct: 266 ITYEINRRQSDPDRVFSINRTSGVVYVNKPLDYEAQAFHELIVSATDNGAQPEHSSTFVG 325 Query: 245 INIRDVNDNAPRFYTSLFQES----VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 + + ++ND++P E+ VSE +G + R+ D D + T+ D Sbjct: 326 VRVLNINDHSPSISVLFLSETGDAAVSEAAGLGDFVARISVSDPDFQ-EERVAVTLEGDD 384 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 G L T D +Y S LDRE + Y+L V A+D G PP S+ Sbjct: 385 --GKFTLKQTADFLYA-LYVSADLDREEKDLYELKVRASDLGSPPLSSEVVFLLRVTDAN 441 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQN 418 F Y V + ED P G+ ++ L A DADE + + Y I N SI ++ Sbjct: 442 DCHPQFEKDAYTVSVPEDVPQGSSLIQLQARDADEGPNGAVRYSILRSNQDRLVSIEPES 501 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTA 476 G L+ A PLD + + V A D G S TA V + + D N+ PVF+ Y A Sbjct: 502 G--LVATAAPLDRESLEQLWFLVVAADGGEPSLSSTATVTVQVLDVNDNEPVFQRQLYGA 559 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 SV E + +G+ L V ATD+D + YSLS + F ++PQ+G + + Sbjct: 560 SVPEHSAVGSCFLQVVATDADSPAFGTLLYSLSDGFDGQ---DQHPLFHVHPQSGELCVS 616 Query: 537 KLLDRET-MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 + +DR++ + + L + A D G LS T V + V D+NDN PVF YT +I A Sbjct: 617 QDIDRDSGQTVHDLLIRAEDPG--GLSAQTYVHVEVEDLNDNAPVFNPDEYTVSISGHAQ 674 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655 G V V ATD D G G++ Y + P D F +DP +G + L A+ L Sbjct: 675 PGAEVLNVIATDRDSGRFGQVTYGIIPGDMSS-LFDVDPQTGTLTLTSPLTDLGAASLQL 733 Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 A DG + +V + + +P VF TF ++E++ GTT+G + A P Sbjct: 734 LLTAQDGEGVMSAKPAVVTVHVLHSARAPAVFHQSRYTFTVAEDATPGTTVGTVEAVTPA 793 Query: 716 -EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP-- 772 EG +A V Y I GD FS+ R G + + LD+E + LVI++ S Sbjct: 794 AEGFSASVSYRISSGDPQGFFSIHPRSGV----ISSTKPLDHEL-QPNVLLVIQSYSDAS 848 Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYR 830 P+++ +V I VTDVNDNAPV + ++ P A+DAD +++YR Sbjct: 849 PVYSTTQVNIAVTDVNDNAPVFLRASDAVSVSQNVLPGTVLYIAHAHDADSGSNGRVRYR 908 Query: 831 ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 L + ++ G++TL L + + +EV DG Sbjct: 909 -LRNDRFGTFGIDRNLGTVTLIQSLLGSRQQSYHLEVVAEDG 949 Score = 308 bits (756), Expect = 2e-81 Identities = 235/760 (30%), Positives = 359/760 (47%), Gaps = 73/760 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I++LD ND++P FE Y +V EG + T V+ + A+D D G N ++EY+I V+ D Sbjct: 2164 IHLLDVNDNAPRFERSSYRTAVWEGQAHNTYVMQMFASDADSGINGQIEYSI--VSGD-- 2219 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P +A F +D G L T LDRE Y ++++A DQ P L Sbjct: 2220 -PNEA--------------FILDSVRGILATSIPLDREITPSYKLVLQAADQGDPP---L 2261 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SSTAT+ V ++D NDN P V + + + ++ A D D+ +S IRY+ Sbjct: 2262 SSTATVRVQVVDVNDNSPAIPHMEPVVIAENRPA---GHTVTQVTANDVDL--SSTIRYS 2316 Query: 191 IIGGNTQ-MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 + G ++ F+I+ +G VSL + LDYE+ Y L + A D + ++ + + D Sbjct: 2317 LSGNSSLGSPFAINQYTGVVSLTRALDYEEQAEYTLTVLASDS---LHQTSGEVKVQVLD 2373 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 +NDNAP F +Q +SE ++ V A D D G N E+TY + G Sbjct: 2374 LNDNAPVFSEDSYQVDLSELATADTLVLSVSATDRDSGPNGEITYRLLSSPLQG-----F 2428 Query: 310 TIDPRSGWVYTSGQLDRETQAKY-QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 I SG ++T+ + LLV A DGGDP S+ A+ F Sbjct: 2429 YIQADSGAIFTNKPIKATANGNLIHLLVEAKDGGDPALSSVASVDVQILDTNDHVPTFHQ 2488 Query: 369 GQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQ-------- 417 Y + + ED P ++TL+A D D + L Y IT GN RF + + Sbjct: 2489 EVYSLTIPEDTPTDATLLTLSAEDQDWSPANTHLDYAITQGNEERRFCLEVRLVPIENQW 2548 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYT 475 G + + LD + YVLTVS +D G + +A+V + + D N+ APVF + Y Sbjct: 2549 RNVGKLVLCNALDRETTDSYVLTVSVSDRGDPPLNSSAVVMLTVADRNDNAPVFSSTEYH 2608 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 A V E +P GT ++ VSA D D+G N+ + + + IS + H+ ++P++G + Sbjct: 2609 AQVSESSPRGTRLVQVSARDPDLGANSLVRFDI---ISGNSKGHYK----LDPESGLLAV 2661 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTD---VEISVVDVNDNEPVFKQQLYTANIME 592 N+ LD E Y+LTV A DGG S V I+V+D NDN P F +++E Sbjct: 2662 NQSLDYEQDPKYILTVRASDGGEFSEKHQVAFAVVFITVLDENDNSPHFVFSTVNCSVLE 2721 Query: 593 DALVGTSVSQVGATDADVGLNGRIHYE-LDP--KDREEGS------FVIDPASGVIRTNK 643 + T V A D D+G G++ Y L P D + GS F IDP +G + T + Sbjct: 2722 NLPAFTHTCSVHAVDNDLGSYGQLTYSILSPCFLDYDSGSPEKKEAFAIDPLTGDVHTRQ 2781 Query: 644 ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703 D E + + A D G +++TV V + I +++ P+F F + +S G Sbjct: 2782 TFDYERESEYCFVVEARDKGG--KTATVRVQVSIRGVDEFSPIFTQKQYHFLLPGHSKPG 2839 Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 +G + A D D G + +V YS+ S FS+ GS Sbjct: 2840 DVVGFVMAMDHDRGVDGIVGYSLV--SSSPFFSVNKTTGS 2877 Score = 304 bits (746), Expect = 2e-80 Identities = 257/853 (30%), Positives = 385/853 (45%), Gaps = 68/853 (7%) Query: 11 INVLDCNDHSP----VFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 + VL+ NDHSP +F + +A+V E A G V + +D D + Sbjct: 326 VRVLNINDHSPSISVLFLSETGDAAVSEAAGLGDFVARISVSDPDFQEER---------V 376 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 A TL +D + AL A LDRE+ Y + V+A+D SP Sbjct: 377 AVTLEGDDGKFTLKQTADFLY----------ALYVSADLDREEKDLYELKVRASDLGSPP 426 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 LSS + + D ND +PQF + YTVSV ED V + +++A DAD G N A Sbjct: 427 ---LSSEVVFLLRVTDANDCHPQFEKDAYTVSVPED--VPQGSSLIQLQARDADEGPNGA 481 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 +RY+I+ N SI+ SG V+ LD E + ++ A DGG PS S+T + + Sbjct: 482 VRYSILRSNQDRLVSIEPESGLVATAAPLDRESLEQLWFLVVAADGGEPSLSSTATVTVQ 541 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + DVNDN P F L+ SV E+ +G ++V A DAD L Y+++D + G Sbjct: 542 VLDVNDNEPVFQRQLYGASVPEHSAVGSCFLQVVATDADSPAFGTLLYSLSD-GFDGQDQ 600 Query: 307 LPIT-IDPRSGWVYTSGQLDRET-QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 P+ + P+SG + S +DR++ Q + LL+ A D G SA Sbjct: 601 HPLFHVHPQSGELCVSQDIDRDSGQTVHDLLIRAEDPGG--LSAQTYVHVEVEDLNDNAP 658 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGL 422 F P +Y V ++ PG V+ + ATD D ++ Y I G+ F + Q G Sbjct: 659 VFNPDEYTVSISGHAQPGAEVLNVIATDRDSGRFGQVTYGIIPGDMSSLFDVDPQTGT-- 716 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480 +T+ PL L ++A D G + A+V +++ + VF + YT +V E Sbjct: 717 LTLTSPLTDLGAASLQLLLTAQDGEGVMSAKPAVVTVHVLHSARAPAVFHQSRYTFTVAE 776 Query: 481 DAPIGTTVLVVSA-TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 DA GTTV V A T + G +A ++Y +SS F I+P++G I++ K L Sbjct: 777 DATPGTTVGTVEAVTPAAEGFSASVSYRISS-------GDPQGFFSIHPRSGVISSTKPL 829 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 D E LL + + P S TT V I+V DVNDN PVF + ++ ++ L GT Sbjct: 830 DHELQPNVLLVIQSYSDASPVYS-TTQVNIAVTDVNDNAPVFLRASDAVSVSQNVLPGTV 888 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 + A DAD G NGR+ Y L ++ G+F ID G + ++L ++ L+ VA Sbjct: 889 LYIAHAHDADSGSNGRVRYRL--RNDRFGTFGIDRNLGTVTLIQSLLGSRQQSYHLEVVA 946 Query: 660 IDGGTPPQSSTVIVHIKIE-DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 DGG P QSS + + + ++ + FE+ I E + + ++ GP Sbjct: 947 EDGGEPAQSSGLSLSVSVDRSAAEDSLAFETLVYQVEIGEGYRKDSRVIQL-------GP 999 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIRAASPPLWN- 776 ++ GD S S S +V LDYE+ ++ ++ AA P L N Sbjct: 1000 R------LRLGDGSRLSSRSVSDSSQVRVVVLAHSLDYETQSAFRFRVLASAAEPSLANT 1053 Query: 777 --DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSG 834 V + V DVNDNAPV F + P G G V A D D Q + Sbjct: 1054 TATAAVTVSVLDVNDNAPVFSRDLYYFTVSEAPSPQGLVGTVSAADKDSGRNAQLSYILL 1113 Query: 835 NNANLILLNETTG 847 ++ +N TG Sbjct: 1114 SDGKFFRINAKTG 1126 Score = 291 bits (714), Expect = 2e-76 Identities = 254/884 (28%), Positives = 402/884 (45%), Gaps = 75/884 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 Q+ +LD ND++P F + Y+ASV EG G VL + A D D G N V Y++ Sbjct: 1853 QLVLLDRNDNAPSFSRKSYQASVSEGLPPGAEVLRVSAFDPDEGPNGRVTYSLT------ 1906 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 ED+ Q F +D +G + T LDRE A+YT+ ATD + Sbjct: 1907 ---EDSS----------QGAFSVDSLTGVIRTTGPLDRESRAQYTLRAVATDGCT--QGP 1951 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L+S A++ V + D NDN P + V N ++A + A D+D G N I++ Sbjct: 1952 LTSVASVTVQVEDVNDNVPICDQNPVNAWV--SARTLPNQIVATVTAEDSDQGENGTIQF 2009 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 A+ + + F I+ +G++S V+ +L + D G P ++T + I+++ Sbjct: 2010 AL--SDEENLFDINRETGEIS-VRRRVRAGFSGRKLEVMVSDRGRPVLTSTCLVFIHLKG 2066 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 N+ +F ++ ++ EN G + +V+A + G + YT+ ++GN + Sbjct: 2067 ENEGL-QFTNKVYNATIKENSGAGILVTKVEA-SGEAGSRQSVVYTI----FSGNENSLF 2120 Query: 310 TIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 +I+ +G + LD E L+V A +G ++ F Sbjct: 2121 SINHHTGEIRVQKDYALDFELSPHIHLVVLADNG---LQTTHCRVSIHLLDVNDNAPRFE 2177 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITV 425 Y + E + T V+ + A+DAD + ++ Y I G+ F + S RG++ Sbjct: 2178 RSSYRTAVWEGQAHNTYVMQMFASDADSGINGQIEYSIVSGDPNEAFILDSV--RGILAT 2235 Query: 426 AQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 + PLD + Y L + A D G S TA V++ + D N+ +P + + E+ P Sbjct: 2236 SIPLDREITPSYKLVLQAADQGDPPLSSTATVRVQVVDVNDNSPAIPHME-PVVIAENRP 2294 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 G TV V+A +DV +++ I YSLS N ++ F IN TG ++ + LD E Sbjct: 2295 AGHTVTQVTA--NDVDLSSTIRYSLS---GNSSLG---SPFAINQYTGVVSLTRALDYEE 2346 Query: 544 MSGYLLTVTARDGGVPSLSDTT-DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 + Y LTV A D SL T+ +V++ V+D+NDN PVF + Y ++ E A T V Sbjct: 2347 QAEYTLTVLASD----SLHQTSGEVKVQVLDLNDNAPVFSEDSYQVDLSELATADTLVLS 2402 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT-HDLKAVAID 661 V ATD D G NG I Y L + F I SG I TNK + + L A D Sbjct: 2403 VSATDRDSGPNGEITYRLLSSPLQ--GFYIQADSGAIFTNKPIKATANGNLIHLLVEAKD 2460 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP-NA 720 GG P SS V ++I D ND P F + + I E++P T+ + A D D P N Sbjct: 2461 GGDPALSSVASVDVQILDTNDHVPTFHQEVYSLTIPEDTPTDATLLTLSAEDQDWSPANT 2520 Query: 721 VVHYSIKGGDDSNSFSLETR------QGSDKAELVTMVDLDYESPRKKYELVIRAA---S 771 + Y+I G++ F LE R Q + +LV LD E+ Y L + + Sbjct: 2521 HLDYAITQGNEERRFCLEVRLVPIENQWRNVGKLVLCNALDRET-TDSYVLTVSVSDRGD 2579 Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADV--TDKLQ 828 PPL + V + V D NDNAPV + + P G +V A D D+ ++ Sbjct: 2580 PPLNSSAVVMLTVADRNDNAPVFSSTE-YHAQVSESSPRGTRLVQVSARDPDLGANSLVR 2638 Query: 829 YRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 + I+SGN+ L+ +G + ++ L+ + V +DG Sbjct: 2639 FDIISGNSKGHYKLDPESGLLAVNQSLDYEQDPKYILTVRASDG 2682 Score = 288 bits (707), Expect = 1e-75 Identities = 220/679 (32%), Positives = 336/679 (49%), Gaps = 47/679 (6%) Query: 88 DVFR---IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDN 144 DVFR ID +G + T LDRE +Y + A+P + + + + + D N Sbjct: 62 DVFRDLEIDADTGLISTAVVLDRESRRQYDFVA-----ATPTGEMIK----VRIEVKDVN 112 Query: 145 DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS 204 D+ P F + + + E + K D D Y I + +F +D Sbjct: 113 DHSPVFPSEGLNLEISEVSPPGSRFKLEGAKDEDEDEFGTQG--YRIRESEMEERFHLDH 170 Query: 205 --------LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256 LS D+ L+ LD E+ Y L I A DGG P R+ T QL I++ D NDN P Sbjct: 171 HRSGSGQHLSLDLVLMSRLDREEQDFYSLTIEAFDGGVPPRTGTLQLRIHVLDENDNPPV 230 Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316 F + + SV E+ P+ + +V A D D G N +TY + + + D +I+ SG Sbjct: 231 FNQTEYHASVPEDAPLMSPVCQVHATDLDLGDNGRITYEINRRQ--SDPDRVFSINRTSG 288 Query: 317 WVYTSGQLDRETQAKYQLLVTATDGG-DPPRSAT---ATXXXXXXXXXXXXXXFMPGQYE 372 VY + LD E QA ++L+V+ATD G P S+T F+ + Sbjct: 289 VVYVNKPLDYEAQAFHELIVSATDNGAQPEHSSTFVGVRVLNINDHSPSISVLFLSETGD 348 Query: 373 VELAEDEPPGTPVVTLTATDAD-EDNRLHYEITGGNTRGRFSIT-SQNGRGLITVAQPLD 430 ++E G V ++ +D D ++ R+ + G + G+F++ + + + V+ LD Sbjct: 349 AAVSEAAGLGDFVARISVSDPDFQEERVAVTLEGDD--GKFTLKQTADFLYALYVSADLD 406 Query: 431 FKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 +++ Y L V A+D G S + + +TDAN+ P FE YT SV ED P G+++ Sbjct: 407 REEKDLYELKVRASDLGSPPLSSEVVFLLRVTDANDCHPQFEKDAYTVSVPEDVPQGSSL 466 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 + + A D+D G N + YS+ SN+ D+ I P++G + T LDRE++ Sbjct: 467 IQLQARDADEGPNGAVRYSILR--SNQ-----DRLVSIEPESGLVATAAPLDRESLEQLW 519 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 V A DGG PSLS T V + V+DVNDNEPVF++QLY A++ E + VG+ QV ATDA Sbjct: 520 FLVVAADGGEPSLSSTATVTVQVLDVNDNEPVFQRQLYGASVPEHSAVGSCFLQVVATDA 579 Query: 609 DVGLNGRIHYEL-DPKDREEGS--FVIDPASGVIRTNKALDRESVAT-HDLKAVAIDGGT 664 D G + Y L D D ++ F + P SG + ++ +DR+S T HDL A D G Sbjct: 580 DSPAFGTLLYSLSDGFDGQDQHPLFHVHPQSGELCVSQDIDRDSGQTVHDLLIRAEDPG- 638 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 S+ VH+++ED+ND+ PVF D T IS ++ G + + A D D G V Y Sbjct: 639 -GLSAQTYVHVEVEDLNDNAPVFNPDEYTVSISGHAQPGAEVLNVIATDRDSGRFGQVTY 697 Query: 725 SIKGGDDSNSFSLETRQGS 743 I GD S+ F ++ + G+ Sbjct: 698 GIIPGDMSSLFDVDPQTGT 716 Score = 284 bits (696), Expect = 3e-74 Identities = 254/928 (27%), Positives = 408/928 (43%), Gaps = 70/928 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI----ELVT 66 ++VLD ND++PVF Y +V E S V T+ A D+D G+NA++ Y + + Sbjct: 1061 VSVLDVNDNAPVFSRDLYYFTVSEAPSPQGLVGTVSAADKDSGRNAQLSYILLSDGKFFR 1120 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 + + ++ + SG ++ +L+RE +++T+ V TDQ P Sbjct: 1121 INAKTGQSPWQLRCFSVAWMRPNALVSP-SGEIINWVALNREHHSQHTLKVMVTDQGHP- 1178 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI--SVTDNPVIAKIKATDADVGAN 184 RL++TAT+H+ + D NDN PQF + V+ I + ++A + A D D G N Sbjct: 1179 --RLNATATVHILVTDTNDNTPQFMHLPASKEVNVQIWAEIPAGSLVANMFAKDLDAGEN 1236 Query: 185 SAIRYAIIGGN--TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 + +++ + F ID +G++ + Y L + A DGG+P + Sbjct: 1237 GTVTFSLASEDEGEPPHFEIDGETGNIRTTEHFTRNTRPFYTLTVCASDGGAPPLEHVAV 1296 Query: 243 LLINIRDVNDNAPRFYTSLFQE-SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 + + + R L + +V E+ + + V A DEG Y++++ D Sbjct: 1297 VHVQVHGSEAVDGRAEHPLVRRFTVREDAEL--ATVIGSARVPDEG---RFRYSISEGD- 1350 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 G+V ID SG +Y + LD E A+Y L+V A G P + + Sbjct: 1351 -GSVQ--FGIDASSGDIYVNQPLDYEAAAQYVLVVRAEGAGLAPGANASVLVSVMVEDAN 1407 Query: 362 XXXXFMPGQYE-VELAEDEPPGTPVVTLTATDAD---EDNRLHY------EITGGNTRGR 411 + P + + L+ED G+ A DAD ++ + Y ++T +TR Sbjct: 1408 DHTPWFPDKMVLLGLSEDATVGSLAFAFQARDADGTFPNSAVRYGLTYDPKVTDSSTRFP 1467 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSD-----TAMVQINITDANNYA 466 F + G +TV PLD + + TV+ATD R + T Q+ + D N+ Sbjct: 1468 FQMNPYTGS--LTVTAPLDRETTSSFAFTVTATDQARRKEERKQATVAAQVFLLDVNDNR 1525 Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL-----SSEISNEAVAHHD 521 PVF +A + V EDA +G+ + A D D G N ++Y++ + E Sbjct: 1526 PVFISA-VSVQVMEDAEVGSLLHRFVAKDGDEGENGLVSYTILTGNKKGMFTLEGNTGKM 1584 Query: 522 QQFVINP-------------QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568 F ++P G + LD E+ + L V A D G+PSLS T Sbjct: 1585 PLFCLHPLCFSVLNLSCLHFSPGLLFLASALDYESQRLHRLIVEAVDHGLPSLSSTQTFT 1644 Query: 569 ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG 628 + V DVND PVF Q +Y A++ E+ G V++V ATD D N + Y L P E Sbjct: 1645 VEVADVNDQPPVFSQSVYNASVAENKDPGEPVARVSATDGDSEENAVVWYSLLPGPGYE- 1703 Query: 629 SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688 F I+P +G+I T LDRE L+ A D G P S+T V + D ND+PP F Sbjct: 1704 LFSINPDTGLITTASYLDREQQHGFTLRVQARDSGPRPLSATATVLCSVLDDNDNPPAFM 1763 Query: 689 SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAEL 748 + EN P G I +A DPD G N + YSI G D + F++ +R G + Sbjct: 1764 QSSFRISLPENLPPG-AIHTAQASDPDLGENGTILYSIVGEDCAGCFTVNSRSG----VV 1818 Query: 749 VTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYK 805 T LD E ++ Y L I+A PL + ++++++ D NDNAP + + Sbjct: 1819 STTKVLDREE-KQNYTLTIQARDYGPTPLSSSTQLQLVLLDRNDNAPSFSRKSYQASVSE 1877 Query: 806 DCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLA 863 P RV A+D D ++ Y + ++ ++ TG + + L+ Sbjct: 1878 GLPPGAEVLRVSAFDPDEGPNGRVTYSLTEDSSQGAFSVDSLTGVIRTTGPLDRESRAQY 1937 Query: 864 TMEVSVTDGVNEIKAMMQLSVRLITEEM 891 T+ TDG + SV + E++ Sbjct: 1938 TLRAVATDGCTQGPLTSVASVTVQVEDV 1965 Score = 248 bits (607), Expect = 2e-63 Identities = 238/817 (29%), Positives = 360/817 (44%), Gaps = 88/817 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D ND P FE Y SV E G++++ L+A D D G N V Y+I D L Sbjct: 435 LRVTDANDCHPQFEKDAYTVSVPEDVPQGSSLIQLQARDADEGPNGAVRYSILRSNQDRL 494 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 I+ SG + T A LDRE + + LV A D P L Sbjct: 495 -------------------VSIEPESGLVATAAPLDRESLEQLWFLVVAADGGEP---SL 532 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SSTAT+ V ++D NDN P F + Y SV E +V ++ ATDAD A + Y+ Sbjct: 533 SSTATVTVQVLDVNDNEPVFQRQLYGASVPEHSAV--GSCFLQVVATDADSPAFGTLLYS 590 Query: 191 IIGG-NTQMQ---FSIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGGSPSRSNTTQLLI 245 + G + Q Q F + SG++ + + +D + ++ + L+IRA+D G S T + + Sbjct: 591 LSDGFDGQDQHPLFHVHPQSGELCVSQDIDRDSGQTVHDLLIRAEDPGGLSAQ--TYVHV 648 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 + D+NDNAP F + S+S + G ++ V A D D G ++TY + D + Sbjct: 649 EVEDLNDNAPVFNPDEYTVSISGHAQPGAEVLNVIATDRDSGRFGQVTYGIIPGDMSSLF 708 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 D +DP++G + + L A QLL+TA DG + A Sbjct: 709 D----VDPQTGTLTLTSPLTDLGAASLQLLLTAQDGEGVMSAKPAVVTVHVLHSARAPAV 764 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTA-TDADE--DNRLHYEITGGNTRGRFSITSQNGRGL 422 F +Y +AED PGT V T+ A T A E + Y I+ G+ +G FSI ++G + Sbjct: 765 FHQSRYTFTVAEDATPGTTVGTVEAVTPAAEGFSASVSYRISSGDPQGFFSIHPRSG--V 822 Query: 423 ITVAQPLDFKQERRYVLTV-SATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 I+ +PLD + + +L + S +D+ T V I +TD N+ APVF A SV ++ Sbjct: 823 ISSTKPLDHELQPNVLLVIQSYSDASPVYSTTQVNIAVTDVNDNAPVFLRASDAVSVSQN 882 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 GT + + A D+D G N ++ Y L ++ F I+ G +T + L Sbjct: 883 VLPGTVLYIAHAHDADSGSNGRVRYRLRNDRFGT--------FGIDRNLGTVTLIQSLLG 934 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVV-DVNDNEPVFKQQLYTANIMEDALVGTSV 600 Y L V A DGG P+ S + +SV ++ F+ +Y I E + V Sbjct: 935 SRQQSYHLEVVAEDGGEPAQSSGLSLSVSVDRSAAEDSLAFETLVYQVEIGEGYRKDSRV 994 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK--AV 658 Q+G +G R L + + S V V+ +LD E+ + + A Sbjct: 995 IQLGPR-LRLGDGSR----LSSRSVSDSSQV-----RVVVLAHSLDYETQSAFRFRVLAS 1044 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE-NSPIGTTIGEIRAHDPDEG 717 A + ++T V + + D+ND+ PVF D F +SE SP G +G + A D D G Sbjct: 1045 AAEPSLANTTATAAVTVSVLDVNDNAPVFSRDLYYFTVSEAPSPQG-LVGTVSAADKDSG 1103 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQG--------------------SDKAELVTMVDL--D 755 NA + Y + D F + + G S E++ V L + Sbjct: 1104 RNAQLSYILL--SDGKFFRINAKTGQSPWQLRCFSVAWMRPNALVSPSGEIINWVALNRE 1161 Query: 756 YESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP 792 + S +V P L V ILVTD NDN P Sbjct: 1162 HHSQHTLKVMVTDQGHPRLNATATVHILVTDTNDNTP 1198 Score = 248 bits (606), Expect = 2e-63 Identities = 183/648 (28%), Positives = 301/648 (46%), Gaps = 38/648 (5%) Query: 52 IGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA 111 I +N +T+ VTA+ ++ + F I+ +G + +LD E+ A Sbjct: 2289 IAENRPAGHTVTQVTANDVDLSSTIRYSLSGNSSLGSPFAINQYTGVVSLTRALDYEEQA 2348 Query: 112 RYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVI 171 YT+ V A+D S + V ++D NDN P FSE +Y V + E T + ++ Sbjct: 2349 EYTLTVLASDSLHQTS------GEVKVQVLDLNDNAPVFSEDSYQVDLSE--LATADTLV 2400 Query: 172 AKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLD-YEQVRSYRLVIRAQ 230 + ATD D G N I Y ++ Q F I + SG + K + L++ A+ Sbjct: 2401 LSVSATDRDSGPNGEITYRLLSSPLQ-GFYIQADSGAIFTNKPIKATANGNLIHLLVEAK 2459 Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVN 289 DGG P+ S+ + + I D ND+ P F+ ++ ++ E+ P +++ + A D D N Sbjct: 2460 DGGDPALSSVASVDVQILDTNDHVPTFHQEVYSLTIPEDTPTDATLLTLSAEDQDWSPAN 2519 Query: 290 AELTYTMTDKDYTGNVDLPITIDP------RSGWVYTSGQLDRETQAKYQLLVTATDGGD 343 L Y +T + L + + P G + LDRET Y L V+ +D GD Sbjct: 2520 THLDYAITQGNEERRFCLEVRLVPIENQWRNVGKLVLCNALDRETTDSYVLTVSVSDRGD 2579 Query: 344 PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHY 401 PP +++A F +Y +++E P GT +V ++A D D ++ + + Sbjct: 2580 PPLNSSAVVMLTVADRNDNAPVFSSTEYHAQVSESSPRGTRLVQVSARDPDLGANSLVRF 2639 Query: 402 EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT-----AMVQ 456 +I GN++G + + ++ GL+ V Q LD++Q+ +Y+LTV A+D G S+ A+V Sbjct: 2640 DIISGNSKGHYKLDPES--GLLAVNQSLDYEQDPKYILTVRASDGGEFSEKHQVAFAVVF 2697 Query: 457 INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI---S 513 I + D N+ +P F + SV E+ P T V A D+D+G Q+TYS+ S Sbjct: 2698 ITVLDENDNSPHFVFSTVNCSVLENLPAFTHTCSVHAVDNDLGSYGQLTYSILSPCFLDY 2757 Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 + + F I+P TG + T + D E S Y V ARD G + T V++S+ Sbjct: 2758 DSGSPEKKEAFAIDPLTGDVHTRQTFDYERESEYCFVVEARDKG--GKTATVRVQVSIRG 2815 Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633 V++ P+F Q+ Y + + G V V A D D G++G + Y L F ++ Sbjct: 2816 VDEFSPIFTQKQYHFLLPGHSKPGDVVGFVMAMDHDRGVDGIVGYSL---VSSSPFFSVN 2872 Query: 634 PASG-VIRTNKALDRESVATHDLKAVAIDGGTPPQSS---TVIVHIKI 677 +G V + R DL + + G+P SS T +V I I Sbjct: 2873 KTTGSVFVSEPVYRRRGSHGEDLVKLLVSAGSPKLSSRTTTCVVFINI 2920 Score = 241 bits (591), Expect = 1e-61 Identities = 231/849 (27%), Positives = 366/849 (43%), Gaps = 84/849 (9%) Query: 104 SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI 163 SLD E + + V A+ A P ++TA + V+++D NDN P FS Y +V E Sbjct: 1028 SLDYETQSAFRFRVLAS-AAEPSLANTTATAAVTVSVLDVNDNAPVFSRDLYYFTVSE-- 1084 Query: 164 SVTDNPVIAKIKATDADVGANSAIRYAIIG-----------GNTQMQ---FSID------ 203 + + ++ + A D D G N+ + Y ++ G + Q FS+ Sbjct: 1085 APSPQGLVGTVSAADKDSGRNAQLSYILLSDGKFFRINAKTGQSPWQLRCFSVAWMRPNA 1144 Query: 204 --SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261 S SG++ L+ E + L + D G P + T + I + D NDN P+F Sbjct: 1145 LVSPSGEIINWVALNREHHSQHTLKVMVTDQGHPRLNATATVHILVTDTNDNTPQFMHLP 1204 Query: 262 FQESVS----ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317 + V+ +P G + + A D D G N +T+++ +D G ID +G Sbjct: 1205 ASKEVNVQIWAEIPAGSLVANMFAKDLDAGENGTVTFSLASED-EGEPP-HFEIDGETGN 1262 Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM-PGQYEVELA 376 + T+ R T+ Y L V A+DGG PP A P + Sbjct: 1263 IRTTEHFTRNTRPFYTLTVCASDGGAPPLEHVAVVHVQVHGSEAVDGRAEHPLVRRFTVR 1322 Query: 377 EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436 ED T + + D + R Y I+ G+ +F I + +G I V QPLD++ + Sbjct: 1323 EDAELATVIGSARVPD---EGRFRYSISEGDGSVQFGIDASSGD--IYVNQPLDYEAAAQ 1377 Query: 437 YVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 YVL V A +G G + + +V + + DAN++ P F + + EDA +G+ A Sbjct: 1378 YVLVVRAEGAGLAPGANASVLVSVMVEDANDHTPWFPDKMVLLGLSEDATVGSLAFAFQA 1437 Query: 494 TDSDVGI-NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552 D+D N+ + Y L+ + + F +NP TG++T LDRET S + TVT Sbjct: 1438 RDADGTFPNSAVRYGLTYD-PKVTDSSTRFPFQMNPYTGSLTVTAPLDRETTSSFAFTVT 1496 Query: 553 ARDGG---VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 A D T ++ ++DVNDN PVF + + +MEDA VG+ + + A D D Sbjct: 1497 ATDQARRKEERKQATVAAQVFLLDVNDNRPVFISAV-SVQVMEDAEVGSLLHRFVAKDGD 1555 Query: 610 VGLNGRIHYELDPKDRE-----EGS------FVIDP-------------ASGVIRTNKAL 645 G NG + Y + +++ EG+ F + P + G++ AL Sbjct: 1556 EGENGLVSYTILTGNKKGMFTLEGNTGKMPLFCLHPLCFSVLNLSCLHFSPGLLFLASAL 1615 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 D ES H L A+D G P SST +++ D+ND PPVF ++EN G Sbjct: 1616 DYESQRLHRLIVEAVDHGLPSLSSTQTFTVEVADVNDQPPVFSQSVYNASVAENKDPGEP 1675 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYE 764 + + A D D NAVV YS+ G FS+ D + T LD E Sbjct: 1676 VARVSATDGDSEENAVVWYSLLPGPGYELFSI----NPDTGLITTASYLDREQQHGFTLR 1731 Query: 765 LVIRAASP-PLWNDVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFPVGPFGRVPAYDA 821 + R + P PL V V D NDN P + F+I + + P G A D Sbjct: 1732 VQARDSGPRPLSATATVLCSVLDDNDNPPAFMQSSFRI---SLPENLPPGAIHTAQASDP 1788 Query: 822 DVTDK--LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKA 878 D+ + + Y I+ + A +N +G ++ + L+ + T+ + D G + + Sbjct: 1789 DLGENGTILYSIVGEDCAGCFTVNSRSGVVSTTKVLDREEKQNYTLTIQARDYGPTPLSS 1848 Query: 879 MMQLSVRLI 887 QL + L+ Sbjct: 1849 STQLQLVLL 1857 Score = 187 bits (455), Expect = 4e-45 Identities = 162/594 (27%), Positives = 265/594 (44%), Gaps = 64/594 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ VLD ND++PVF Y+ + E A++ T VL++ ATD+D G N E+ Y + Sbjct: 2368 KVQVLDLNDNAPVFSEDSYQVDLSELATADTLVLSVSATDRDSGPNGEITYRL------- 2420 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYT-VLVKATDQASPVSD 128 +Q F I SGA+ T + +LV+A D P Sbjct: 2421 ------------LSSPLQG-FYIQADSGAIFTNKPIKATANGNLIHLLVEAKDGGDPA-- 2465 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG-ANSAI 187 LSS A++ V I+D ND+ P F ++ Y++++ ED + TD ++ + A D D AN+ + Sbjct: 2466 -LSSVASVDVQILDTNDHVPTFHQEVYSLTIPED-TPTDATLLT-LSAEDQDWSPANTHL 2522 Query: 188 RYAIIGGNTQMQFSIDSLS----------GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237 YAI GN + +F ++ G + L LD E SY L + D G P Sbjct: 2523 DYAITQGNEERRFCLEVRLVPIENQWRNVGKLVLCNALDRETTDSYVLTVSVSDRGDPPL 2582 Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297 +++ +++ + D NDNAP F ++ + VSE+ P G +V+V A D D G N+ + + + Sbjct: 2583 NSSAVVMLTVADRNDNAPVFSSTEYHAQVSESSPRGTRLVQVSARDPDLGANSLVRFDII 2642 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD---PPRSATATXXX 354 + G+ L DP SG + + LD E KY L V A+DGG+ + A A Sbjct: 2643 SGNSKGHYKL----DPESGLLAVNQSLDYEQDPKYILTVRASDGGEFSEKHQVAFAVVFI 2698 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITG------- 405 F+ + E+ P T ++ A D D + +L Y I Sbjct: 2699 TVLDENDNSPHFVFSTVNCSVLENLPAFTHTCSVHAVDNDLGSYGQLTYSILSPCFLDYD 2758 Query: 406 -GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANN 464 G+ + + G + Q D+++E Y V A D GG++ T VQ++I + Sbjct: 2759 SGSPEKKEAFAIDPLTGDVHTRQTFDYERESEYCFVVEARDKGGKTATVRVQVSIRGVDE 2818 Query: 465 YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524 ++P+F Y + + G V V A D D G++ + YSL S F Sbjct: 2819 FSPIFTQKQYHFLLPGHSKPGDVVGFVMAMDHDRGVDGIVGYSLVSS---------SPFF 2869 Query: 525 VINPQTGAITTNKLLDRETMS-GYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577 +N TG++ ++ + R S G L G P LS T + ++++ + Sbjct: 2870 SVNKTTGSVFVSEPVYRRRGSHGEDLVKLLVSAGSPKLSSRTTTCVVFINISSS 2923 Score = 173 bits (422), Expect = 4e-41 Identities = 149/501 (29%), Positives = 229/501 (45%), Gaps = 44/501 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIG-KNAEVEYTIELVTADT 69 + +LD NDH P F + Y ++ E + T+LTL A DQD N ++Y I T Sbjct: 2474 VQILDTNDHVPTFHQEVYSLTIPEDTPTDATLLTLSAEDQDWSPANTHLDYAI------T 2527 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 E+ +++ +R G L+ +LDRE Y + V +D+ P Sbjct: 2528 QGNEERRFCLEVRLVPIENQWR---NVGKLVLCNALDRETTDSYVLTVSVSDRGDP---P 2581 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L+S+A + + + D NDN P FS Y V E S + ++ A D D+GANS +R+ Sbjct: 2582 LNSSAVVMLTVADRNDNAPVFSSTEYHAQVSE--SSPRGTRLVQVSARDPDLGANSLVRF 2639 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ---LLIN 246 II GN++ + +D SG +++ ++LDYEQ Y L +RA DGG S + + I Sbjct: 2640 DIISGNSKGHYKLDPESGLLAVNQSLDYEQDPKYILTVRASDGGEFSEKHQVAFAVVFIT 2699 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK---DY-T 302 + D NDN+P F S SV EN+P V A D D G +LTY++ DY + Sbjct: 2700 VLDENDNSPHFVFSTVNCSVLENLPAFTHTCSVHAVDNDLGSYGQLTYSILSPCFLDYDS 2759 Query: 303 GNVDL--PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 G+ + IDP +G V+T D E +++Y +V A D G ++AT Sbjct: 2760 GSPEKKEAFAIDPLTGDVHTRQTFDYERESEYCFVVEARDKGG--KTATVRVQVSIRGVD 2817 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQN 418 F QY L PG V + A D D D + Y + + FS+ Sbjct: 2818 EFSPIFTQKQYHFLLPGHSKPGDVVGFVMAMDHDRGVDGIVGYSLVSSSP--FFSVNKTT 2875 Query: 419 GRGLITVAQPLDFKQ----ERRYVLTVSATDS--GGRSDTAMVQINITDANNYAPVFENA 472 G + V++P+ ++ E L VSA R+ T +V INI+ + A A Sbjct: 2876 GS--VFVSEPVYRRRGSHGEDLVKLLVSAGSPKLSSRTTTCVVFINISSS---AEALAGA 2930 Query: 473 PYTASVFEDAPIGTTVLVVSA 493 P A + +G +++V+ A Sbjct: 2931 PLDAHMLS---LGVSLVVILA 2948 Score = 41.5 bits (93), Expect = 0.32 Identities = 35/104 (33%), Positives = 52/104 (50%), Gaps = 13/104 (12%) Query: 692 LTFYISENSPIGTTIGEIRA--HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV 749 LT + E P GT +G++ A P G + I DS+ F + +D + Sbjct: 25 LTLSVKEGLPAGTIVGDLGAVLSAPSTG------FFISESRDSDVFR-DLEIDADTGLIS 77 Query: 750 TMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPV 793 T V LD ES R++Y+ V A+ P ++V I V DVND++PV Sbjct: 78 TAVVLDRES-RRQYDFV---AATPTGEMIKVRIEVKDVNDHSPV 117 >UniRef50_A7S5N5 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1610 Score = 333 bits (818), Expect = 5e-89 Identities = 242/790 (30%), Positives = 374/790 (47%), Gaps = 57/790 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +N+LD ND+ PVF+ Y A+V E AS G TVL ++A D D+ NA V Y+I V+ +T Sbjct: 852 VNLLDVNDNDPVFDRDVYTANVSEDASPGLTVLKIRAVDNDLASNANVSYSI--VSGNT- 908 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F +D +G + + L+REK+ YT+ V + D + V R Sbjct: 909 ----------------GAAFHVDNVTGEIKLVSKLEREKITSYTLTVGSADGGA-VPRR- 950 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 STA + + ++D NDN P T TV + E++ + K+ TD D N + Y Sbjct: 951 -STALVIIYVMDVNDNSPVCLHDTQTVRLLENLPA--GHFVVKVVTTDPDEVHNGRVEYN 1007 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + T F +D +G ++ + LD E + +Y L++ A++ S + + + D Sbjct: 1008 L----TSDAFRVDPFTGIITTTRALDRESIPAYNLMVTARNSNSSDMEVNCSVHVIVMDT 1063 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 ND+ P F + + S E P+G ++ RV+A D D+G+NAE+ YT+ ++ Sbjct: 1064 NDHTPSFTMARYYISTPETTPVGSTLFRVRAVDGDDGINAEVRYTLMGEESL------FR 1117 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX-XFMPG 369 I+ +G V LDRE +A+YQL V A D G P +A +T F Sbjct: 1118 INYTTGIVTLVSSLDRENKAQYQLEVEARDRGIPESNANSTTILIRVGDVNDNRPTFTHA 1177 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQ 427 Y+ + E + G + A D DE+ + Y I GGNT F+I +++G + T+ Sbjct: 1178 HYDGNVLEGQV-GAVAAIVVALDKDEEINADIVYSIIGGNTDNSFAINNKSG-SIYTLLH 1235 Query: 428 PLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 LD + RY+LTV A+D G + + V I++ D N+ P N P E+ P G Sbjct: 1236 -LDRETTDRYILTVLASDRGEPAMNSSTNVTIHVNDVNDNKPNITNNPGVVVTRENTPPG 1294 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 + V ++SA+D D G NA++ +S A D +F I P G I LDRE + Sbjct: 1295 SLVYILSASDLDEGSNARVAFS--------GYAVPDGKFSIKPN-GEIMVRDSLDREAQN 1345 Query: 546 GYLLTVTARDGGVPSL-SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 ++ A D G P S +I + D NDN PVF Y+ NI E+ + QV Sbjct: 1346 RFVFYAMATDSGQPPFNSSMVSFDILIADENDNNPVFDPVHYSVNISENGPSEEVIVQVN 1405 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 A++ D G++ +++ D G F I +GVI T K LDRE V+ DL A D G Sbjct: 1406 ASERD---EGKLLFKISSGD-PGGYFTIHNVTGVISTRKPLDREMVSRFDLTITAEDEGR 1461 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 P + + V I + D ND PV E +SEN+ IG+ + I A D D+ N + Y Sbjct: 1462 PSRMALGYVTIFVNDENDFAPVIEQCEQLVSVSENAHIGSAVASINAVDKDDPSNTKITY 1521 Query: 725 SI-KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEIL 783 S+ + + L GS ++ L + Y + + A+ + + Sbjct: 1522 SVGNSAFNITTQRLPFSSGSRYRGIIITAGLLDRERQDNYNITVTASDGNHIATCNIIVR 1581 Query: 784 VTDVNDNAPV 793 +TDVNDN+PV Sbjct: 1582 ITDVNDNSPV 1591 Score = 330 bits (812), Expect = 2e-88 Identities = 263/881 (29%), Positives = 411/881 (46%), Gaps = 71/881 (8%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 I+ INVLD ND+ PV + Y S+ E S G +++ L TDQD G+NA + Y +V+ Sbjct: 633 INVTINVLDSNDNIPVCDKVYYTISIPENTSVGQSLIHLNCTDQDSGENAHLLY--HMVS 690 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLD-REKVARYTVLVKATDQASP 125 + F +D +G + LD EK +TV ++ D P Sbjct: 691 GHSK-------------------FVVDNVTGIMSLNKLLDFEEKPTVFTVAIEVIDHGRP 731 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 LS ++V + + NDNYP F + YT + E D+ ++ + A D D +++ Sbjct: 732 P---LSLVVFVNVTVDNVNDNYPSFGQDNYTFWISEGDFAVDHAIVGVVSAHDLDADSSN 788 Query: 186 A-----IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS-- 238 ++Y + GN+ F+ID +G + V +LD E +++Y + AQD P+R Sbjct: 789 CPLCGKLQYTL--GNSTGPFAIDKDTGVLRAVGSLDREGIKNYTFSVIAQD-SIPNRPLV 845 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 N T + +N+ DVNDN P F ++ +VSE+ G ++++++A D D NA ++Y++ Sbjct: 846 NVTMVTVNLLDVNDNDPVFDRDVYTANVSEDASPGLTVLKIRAVDNDLASNANVSYSIV- 904 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358 +GN +D +G + +L+RE Y L V + DGG PR +TA Sbjct: 905 ---SGNTGAAFHVDNVTGEIKLVSKLEREKITSYTLTVGSADGGAVPRRSTALVIIYVMD 961 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITS 416 + V L E+ P G VV + TD DE + R+ Y +T R Sbjct: 962 VNDNSPVCLHDTQTVRLLENLPAGHFVVKVVTTDPDEVHNGRVEYNLTSDAFR------V 1015 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSA--TDSGGRSDTAMVQINITDANNYAPVFENAPY 474 G+IT + LD + Y L V+A ++S V + + D N++ P F A Y Sbjct: 1016 DPFTGIITTTRALDRESIPAYNLMVTARNSNSSDMEVNCSVHVIVMDTNDHTPSFTMARY 1075 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 S E P+G+T+ V A D D GINA++ Y+L E + F IN TG +T Sbjct: 1076 YISTPETTPVGSTLFRVRAVDGDDGINAEVRYTLMGE---------ESLFRINYTTGIVT 1126 Query: 535 TNKLLDRETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593 LDRE + Y L V ARD G+P S +++T + I V DVNDN P F Y N++E Sbjct: 1127 LVSSLDRENKAQYQLEVEARDRGIPESNANSTTILIRVGDVNDNRPTFTHAHYDGNVLE- 1185 Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653 VG + V A D D +N I Y + + SF I+ SG I T LDRE+ + Sbjct: 1186 GQVGAVAAIVVALDKDEEINADIVYSI-IGGNTDNSFAINNKSGSIYTLLHLDRETTDRY 1244 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713 L +A D G P +S+ V I + D+ND+ P ++ EN+P G+ + + A D Sbjct: 1245 ILTVLASDRGEPAMNSSTNVTIHVNDVNDNKPNITNNPGVVVTRENTPPGSLVYILSASD 1304 Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK--KYELVIRAAS 771 DEG NA V +S D FS++ E++ LD E+ + Y + + Sbjct: 1305 LDEGSNARVAFSGYAVPD-GKFSIK-----PNGEIMVRDSLDREAQNRFVFYAMATDSGQ 1358 Query: 772 PPLWND-VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYR 830 PP + V +IL+ D NDN PV N ++ +V A + D KL ++ Sbjct: 1359 PPFNSSMVSFDILIADENDNNPVFDPVHYSVNISENGPSEEVIVQVNASERD-EGKLLFK 1417 Query: 831 ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 I SG+ ++ TG ++ L+ + + ++ D Sbjct: 1418 ISSGDPGGYFTIHNVTGVISTRKPLDREMVSRFDLTITAED 1458 Score = 328 bits (806), Expect = 1e-87 Identities = 272/864 (31%), Positives = 395/864 (45%), Gaps = 83/864 (9%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 D ND+SP+F Y + + E GT V+ + A D DIG NA V Y + D Sbjct: 421 DENDNSPIFSRALYSSPIYENEPPGTFVIQVSANDSDIGSNAMVSYAVL---------SD 471 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134 A F+I+ ++G + T LDRE + + + V A+D A P+S S Sbjct: 472 AEGHY--------QYFKINAKNGTITTSRRLDRENITTFRLRVTASDGA-PLSTIRVSVV 522 Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194 + V ++D NDN P+F +Y SV E + ++ I A D D N I Y I G Sbjct: 523 DVVVTVLDINDNSPEFVRPSYNFSVIE--TALPGAILGIISAVDRDKDLNGNIVYIITEG 580 Query: 195 NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP-----SRSNTT-QLLINIR 248 N + F I + SG + L TLD E V + L + A D G S NTT + IN+ Sbjct: 581 NVEGSFIIGARSGLLQLNHTLDREVVSKHSLRVTASDRGGEFMADGSSLNTTINVTINVL 640 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D NDN P + S+ EN +G S++ + D D G NA L Y M +G+ Sbjct: 641 DSNDNIPVCDKVYYTISIPENTSVGQSLIHLNCTDQDSGENAHLLYHMV----SGH--SK 694 Query: 309 ITIDPRSGWVYTSGQLD-RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 +D +G + + LD E + + + D G PP S F Sbjct: 695 FVVDNVTGIMSLNKLLDFEEKPTVFTVAIEVIDHGRPPLSLVVFVNVTVDNVNDNYPSFG 754 Query: 368 PGQYEVELAED----EPPGTPVVTLTATDADEDN-----RLHYEITGGNTRGRFSITSQN 418 Y ++E + VV+ DAD N +L Y T GN+ G F+I Sbjct: 755 QDNYTFWISEGDFAVDHAIVGVVSAHDLDADSSNCPLCGKLQY--TLGNSTGPFAIDKDT 812 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRS---DTAMVQINITDANNYAPVFENAPYT 475 G++ LD + + Y +V A DS + MV +N+ D N+ PVF+ YT Sbjct: 813 --GVLRAVGSLDREGIKNYTFSVIAQDSIPNRPLVNVTMVTVNLLDVNDNDPVFDRDVYT 870 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 A+V EDA G TVL + A D+D+ NA ++YS+ S N A H ++ TG I Sbjct: 871 ANVSEDASPGLTVLKIRAVDNDLASNANVSYSIVS--GNTGAAFH-----VDNVTGEIKL 923 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 L+RE ++ Y LTV + DGG T V I V+DVNDN PV T ++E+ Sbjct: 924 VSKLEREKITSYTLTVGSADGGAVPRRSTALVIIYVMDVNDNSPVCLHDTQTVRLLENLP 983 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655 G V +V TD D NGR+ Y L +F +DP +G+I T +ALDRES+ ++L Sbjct: 984 AGHFVVKVVTTDPDEVHNGRVEYNL-----TSDAFRVDPFTGIITTTRALDRESIPAYNL 1038 Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS--ENSPIGTTIGEIRAHD 713 A + + VH+ + D ND P F +YIS E +P+G+T+ +RA D Sbjct: 1039 MVTARNSNSSDMEVNCSVHVIVMDTNDHTPSF--TMARYYISTPETTPVGSTLFRVRAVD 1096 Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRAASP 772 D+G NA V Y++ G + + F + G +VT+V LD E+ + +Y+L + A Sbjct: 1097 GDDGINAEVRYTLMG--EESLFRINYTTG-----IVTLVSSLDREN-KAQYQLEVEARDR 1148 Query: 773 PL----WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR-VPAYDAD--VTD 825 + N + I V DVNDN P N + VG V A D D + Sbjct: 1149 GIPESNANSTTILIRVGDVNDNRPTFTHAHYDGNVLEG--QVGAVAAIVVALDKDEEINA 1206 Query: 826 KLQYRILSGNNANLILLNETTGSM 849 + Y I+ GN N +N +GS+ Sbjct: 1207 DIVYSIIGGNTDNSFAINNKSGSI 1230 Score = 327 bits (804), Expect = 2e-87 Identities = 235/757 (31%), Positives = 359/757 (47%), Gaps = 44/757 (5%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F ID +G L SLDRE + YT V A D S + L + + VN++D NDN P Sbjct: 806 FAIDKDTGVLRAVGSLDREGIKNYTFSVIAQD--SIPNRPLVNVTMVTVNLLDVNDNDPV 863 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209 F YT +V ED S + KI+A D D+ +N+ + Y+I+ GNT F +D+++G++ Sbjct: 864 FDRDVYTANVSEDAS--PGLTVLKIRAVDNDLASNANVSYSIVSGNTGAAFHVDNVTGEI 921 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269 LV L+ E++ SY L + + DGG+ R +T ++I + DVNDN+P + EN Sbjct: 922 KLVSKLEREKITSYTLTVGSADGGAVPRRSTALVIIYVMDVNDNSPVCLHDTQTVRLLEN 981 Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329 +P G+ +V+V D DE N + Y +T + +DP +G + T+ LDRE+ Sbjct: 982 LPAGHFVVKVVTTDPDEVHNGRVEYNLTSDAF--------RVDPFTGIITTTRALDRESI 1033 Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389 Y L+VTA + + F +Y + E P G+ + + Sbjct: 1034 PAYNLMVTARNSNSSDMEVNCSVHVIVMDTNDHTPSFTMARYYISTPETTPVGSTLFRVR 1093 Query: 390 ATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447 A D D+ + + Y + G + R + T+ G++T+ LD + + +Y L V A D G Sbjct: 1094 AVDGDDGINAEVRYTLMGEESLFRINYTT----GIVTLVSSLDRENKAQYQLEVEARDRG 1149 Query: 448 ---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504 +++ + I + D N+ P F +A Y +V E +G +V A D D INA I Sbjct: 1150 IPESNANSTTILIRVGDVNDNRPTFTHAHYDGNVLE-GQVGAVAAIVVALDKDEEINADI 1208 Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT 564 YS+ + D F IN ++G+I T LDRET Y+LTV A D G P+++ + Sbjct: 1209 VYSIIG-------GNTDNSFAINNKSGSIYTLLHLDRETTDRYILTVLASDRGEPAMNSS 1261 Query: 565 TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624 T+V I V DVNDN+P E+ G+ V + A+D D G N R+ + Sbjct: 1262 TNVTIHVNDVNDNKPNITNNPGVVVTRENTPPGSLVYILSASDLDEGSNARVAF--SGYA 1319 Query: 625 REEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP-QSSTVIVHIKIEDINDS 683 +G F I P +G I +LDRE+ A+A D G PP SS V I I D ND+ Sbjct: 1320 VPDGKFSIKP-NGEIMVRDSLDREAQNRFVFYAMATDSGQPPFNSSMVSFDILIADENDN 1378 Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 PVF+ + ISEN P I ++ A + DEG + + I GD F++ G Sbjct: 1379 NPVFDPVHYSVNISENGPSEEVIVQVNASERDEGK---LLFKISSGDPGGYFTIHNVTG- 1434 Query: 744 DKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQII 800 + T LD E +++L I A P V I V D ND APV++ + + Sbjct: 1435 ---VISTRKPLDREMV-SRFDLTITAEDEGRPSRMALGYVTIFVNDENDFAPVIEQCEQL 1490 Query: 801 FNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNA 837 + ++ + A D D + GN+A Sbjct: 1491 VSVSENAHIGSAVASINAVDKDDPSNTKITYSVGNSA 1527 Score = 314 bits (772), Expect = 2e-83 Identities = 244/799 (30%), Positives = 380/799 (47%), Gaps = 65/799 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND+SP F Y SV E A G + + A D+D N + Y I Sbjct: 526 VTVLDINDNSPEFVRPSYNFSVIETALPGAILGIISAVDRDKDLNGNIVYII-------- 577 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV---S 127 V+ F I RSG L +LDRE V+++++ V A+D+ Sbjct: 578 -----------TEGNVEGSFIIGARSGLLQLNHTLDREVVSKHSLRVTASDRGGEFMADG 626 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 L++T + +N++D NDN P + YT+S+ E+ SV + + + TD D G N+ + Sbjct: 627 SSLNTTINVTINVLDSNDNIPVCDKVYYTISIPENTSVGQS--LIHLNCTDQDSGENAHL 684 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGGSPSRSNTTQLLIN 246 Y ++ G++ +F +D+++G +SL K LD+E+ + + + I D G P S + + Sbjct: 685 LYHMVSGHS--KFVVDNVTGIMSLNKLLDFEEKPTVFTVAIEVIDHGRPPLSLVVFVNVT 742 Query: 247 IRDVNDNAPRFYTSLFQESVSE-NVPIGYSIVR-VQAYDAD-EGVNAELTYTMTDKDYT- 302 + +VNDN P F + +SE + + ++IV V A+D D + N L + YT Sbjct: 743 VDNVNDNYPSFGQDNYTFWISEGDFAVDHAIVGVVSAHDLDADSSNCPLCGKL---QYTL 799 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG-GDPPRSATATXXXXXXXXXX 361 GN P ID +G + G LDRE Y V A D + P Sbjct: 800 GNSTGPFAIDKDTGVLRAVGSLDREGIKNYTFSVIAQDSIPNRPLVNVTMVTVNLLDVND 859 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419 F Y ++ED PG V+ + A D D + + Y I GNT F + N Sbjct: 860 NDPVFDRDVYTANVSEDASPGLTVLKIRAVDNDLASNANVSYSIVSGNTGAAFHV--DNV 917 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTAS 477 G I + L+ ++ Y LTV + D G R TA+V I + D N+ +PV + T Sbjct: 918 TGEIKLVSKLEREKITSYTLTVGSADGGAVPRRSTALVIIYVMDVNDNSPVCLHDTQTVR 977 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 + E+ P G V+ V TD D N ++ Y+L+S+ F ++P TG ITT + Sbjct: 978 LLENLPAGHFVVKVVTTDPDEVHNGRVEYNLTSD-----------AFRVDPFTGIITTTR 1026 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LDRE++ Y L VTAR+ + V + V+D ND+ P F Y + E VG Sbjct: 1027 ALDRESIPAYNLMVTARNSNSSDMEVNCSVHVIVMDTNDHTPSFTMARYYISTPETTPVG 1086 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 +++ +V A D D G+N + Y L EE F I+ +G++ +LDRE+ A + L+ Sbjct: 1087 STLFRVRAVDGDDGINAEVRYTL---MGEESLFRINYTTGIVTLVSSLDRENKAQYQLEV 1143 Query: 658 VAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 A D G P +++ + I++ D+ND+ P F + E +G + A D DE Sbjct: 1144 EARDRGIPESNANSTTILIRVGDVNDNRPTFTHAHYDGNVLEGQ-VGAVAAIVVALDKDE 1202 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPP 773 NA + YSI GG+ NSF++ + GS + T++ LD E+ +Y L + A+ P Sbjct: 1203 EINADIVYSIIGGNTDNSFAINNKSGS----IYTLLHLDRET-TDRYILTVLASDRGEPA 1257 Query: 774 LWNDVRVEILVTDVNDNAP 792 + + V I V DVNDN P Sbjct: 1258 MNSSTNVTIHVNDVNDNKP 1276 Score = 303 bits (745), Expect = 3e-80 Identities = 248/817 (30%), Positives = 398/817 (48%), Gaps = 77/817 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NVLD +D F Y AS+ E A+ G+ V+ + A D D NA V Y I+ T Sbjct: 210 VNVLDADDLPVRFNNYSYSASIPENAAMGSVVMQVHAKDLDKSINAPVTYAIDKET---- 265 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 NP +F I +G + SLDRE +A Y + + A + D Sbjct: 266 NP--------------LRMFNIANITGEITLNGSLDRETIAEYRLRILA--YCTIYQDHT 309 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + + + D NDN P F+ +Y +V+E+ ++ + +++A D D G N++ Y Sbjct: 310 E----VLITVTDVNDNIPLFTLPSYNTTVNENAAI--GTYVIQVQAEDIDQGVNASFIYE 363 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS--RSNTTQLLINIR 248 I +F I SG + + TLD E+ Y + + A++ + + SN T + + +R Sbjct: 364 I--AYAGHEFVIGEHSGIIIVNGTLDREKKDLYSITVIARETETSAGFHSNVT-ITVMLR 420 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D NDN+P F +L+ + EN P G +++V A D+D G NA ++Y + D G+ Sbjct: 421 DENDNSPIFSRALYSSPIYENEPPGTFVIQVSANDSDIGSNAMVSYAVL-SDAEGHYQY- 478 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG--DPPRSATATXXXXXXXXXXXXXXF 366 I+ ++G + TS +LDRE ++L VTA+DG R + F Sbjct: 479 FKINAKNGTITTSRRLDRENITTFRLRVTASDGAPLSTIRVSVVDVVVTVLDINDNSPEF 538 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLIT 424 + Y + E PG + ++A D D+D + Y IT GN G F I +++ GL+ Sbjct: 539 VRPSYNFSVIETALPGAILGIISAVDRDKDLNGNIVYIITEGNVEGSFIIGARS--GLLQ 596 Query: 425 VAQPLDFKQERRYVLTVSATDSGGR--------SDTAMVQINITDANNYAPVFENAPYTA 476 + LD + ++ L V+A+D GG + T V IN+ D+N+ PV + YT Sbjct: 597 LNHTLDREVVSKHSLRVTASDRGGEFMADGSSLNTTINVTINVLDSNDNIPVCDKVYYTI 656 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 S+ E+ +G +++ ++ TD D G NA + Y + V+ H +FV++ TG ++ N Sbjct: 657 SIPENTSVGQSLIHLNCTDQDSGENAHLLYHM--------VSGH-SKFVVDNVTGIMSLN 707 Query: 537 KLLD-RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME--- 592 KLLD E + + + + D G P LS V ++V +VNDN P F Q YT I E Sbjct: 708 KLLDFEEKPTVFTVAIEVIDHGRPPLSLVVFVNVTVDNVNDNYPSFGQDNYTFWISEGDF 767 Query: 593 ---DALVG-TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648 A+VG S + A ++ L G++ Y L G F ID +GV+R +LDRE Sbjct: 768 AVDHAIVGVVSAHDLDADSSNCPLCGKLQYTL---GNSTGPFAIDKDTGVLRAVGSLDRE 824 Query: 649 SVATHDLKAVAIDG-GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 + + +A D P + +V + + D+ND+ PVF+ D T +SE++ G T+ Sbjct: 825 GIKNYTFSVIAQDSIPNRPLVNVTMVTVNLLDVNDNDPVFDRDVYTANVSEDASPGLTVL 884 Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 +IRA D D NA V YSI G+ +F ++ G K LV+ ++ + + Y L + Sbjct: 885 KIRAVDNDLASNANVSYSIVSGNTGAAFHVDNVTGEIK--LVSKLEREKIT---SYTLTV 939 Query: 768 RAA---SPPLWNDVRVEILVTDVNDNAPV-MKDFQII 800 +A + P + V I V DVNDN+PV + D Q + Sbjct: 940 GSADGGAVPRRSTALVIIYVMDVNDNSPVCLHDTQTV 976 Score = 300 bits (736), Expect = 4e-79 Identities = 251/868 (28%), Positives = 408/868 (47%), Gaps = 76/868 (8%) Query: 36 ASSGTTVLTLKATDQDIGK-NAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDG 94 ++SG +VLT+ ATD D + N V Y I V+ + ED +F ID Sbjct: 122 STSGLSVLTMSATDMDAEEINQRVNYAI--VSGN----EDG-------------IFDIDF 162 Query: 95 RSGALLTRASLDREKVARYTVLVKA----TDQASPVSDRLSSTATIHVNIIDDNDNYPQF 150 G + LD E++ +Y + + A T+ + LS+ + VN++D +D +F Sbjct: 163 NKGVIRLARELDFEQMTQYKLNISASNPLTNDTVIPKNGLSNWTMVTVNVLDADDLPVRF 222 Query: 151 SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ-FSIDSLSGDV 209 + +Y+ S+ E+ ++ V+ ++ A D D N+ + YAI ++ F+I +++G++ Sbjct: 223 NNYSYSASIPENAAM--GSVVMQVHAKDLDKSINAPVTYAIDKETNPLRMFNIANITGEI 280 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269 +L +LD E + YRL I A + T++LI + DVNDN P F + +V+EN Sbjct: 281 TLNGSLDRETIAEYRLRILAY---CTIYQDHTEVLITVTDVNDNIPLFTLPSYNTTVNEN 337 Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329 IG +++VQA D D+GVNA Y + Y G+ I SG + +G LDRE + Sbjct: 338 AAIGTYVIQVQAEDIDQGVNASFIYEIA---YAGH---EFVIGEHSGIIIVNGTLDREKK 391 Query: 330 AKYQLLVTATDGGDPPR-SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388 Y + V A + + T F Y + E+EPPGT V+ + Sbjct: 392 DLYSITVIARETETSAGFHSNVTITVMLRDENDNSPIFSRALYSSPIYENEPPGTFVIQV 451 Query: 389 TATDAD--EDNRLHYEITGGNTRGRFSITSQNGR-GLITVAQPLDFKQERRYVLTVSATD 445 +A D+D + + Y + + G + N + G IT ++ LD + + L V+A+D Sbjct: 452 SANDSDIGSNAMVSYAVLS-DAEGHYQYFKINAKNGTITTSRRLDRENITTFRLRVTASD 510 Query: 446 SGGRSDTAM----VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501 S + V + + D N+ +P F Y SV E A G + ++SA D D +N Sbjct: 511 GAPLSTIRVSVVDVVVTVLDINDNSPEFVRPSYNFSVIETALPGAILGIISAVDRDKDLN 570 Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP-- 559 I Y ++ + + F+I ++G + N LDRE +S + L VTA D G Sbjct: 571 GNIVYIITE-------GNVEGSFIIGARSGLLQLNHTLDREVVSKHSLRVTASDRGGEFM 623 Query: 560 ----SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615 SL+ T +V I+V+D NDN PV + YT +I E+ VG S+ + TD D G N Sbjct: 624 ADGSSLNTTINVTINVLDSNDNIPVCDKVYYTISIPENTSVGQSLIHLNCTDQDSGENAH 683 Query: 616 IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV-AIDGGTPPQSSTVIVH 674 + Y + FV+D +G++ NK LD E T A+ ID G PP S V V+ Sbjct: 684 LLYHMVSG---HSKFVVDNVTGIMSLNKLLDFEEKPTVFTVAIEVIDHGRPPLSLVVFVN 740 Query: 675 IKIEDINDSPPVFESDCLTFYISEN--SPIGTTIGEIRAHDPD-EGPNAVVHYSIKG--G 729 + ++++ND+ P F D TF+ISE + +G + AHD D + N + ++ G Sbjct: 741 VTVDNVNDNYPSFGQDNYTFWISEGDFAVDHAIVGVVSAHDLDADSSNCPLCGKLQYTLG 800 Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIRAASP--PLWNDVRVEILVTD 786 + + F+++ D L + LD E + + ++ + + P PL N V + + D Sbjct: 801 NSTGPFAID----KDTGVLRAVGSLDREGIKNYTFSVIAQDSIPNRPLVNVTMVTVNLLD 856 Query: 787 VNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNNANLILLNE 844 VNDN PV N +D P ++ A D D+ + Y I+SGN ++ Sbjct: 857 VNDNDPVFDRDVYTANVSEDASPGLTVLKIRAVDNDLASNANVSYSIVSGNTGAAFHVDN 916 Query: 845 TTGSMTLSPQLNTNVPKLATMEVSVTDG 872 TG + L +L T+ V DG Sbjct: 917 VTGEIKLVSKLEREKITSYTLTVGSADG 944 Score = 283 bits (693), Expect = 6e-74 Identities = 217/700 (31%), Positives = 334/700 (47%), Gaps = 61/700 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V+D ND+SPV + E +G V+ + TD D N VEY + Sbjct: 957 IYVMDVNDNSPVCLHDTQTVRLLENLPAGHFVVKVVTTDPDEVHNGRVEYNL-------- 1008 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 D FR+D +G + T +LDRE + Y ++V A + S SD + Sbjct: 1009 ---------------TSDAFRVDPFTGIITTTRALDRESIPAYNLMVTARNSNS--SD-M 1050 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 ++HV ++D ND+ P F+ Y +S E V + +++A D D G N+ +RY Sbjct: 1051 EVNCSVHVIVMDTNDHTPSFTMARYYISTPETTPV--GSTLFRVRAVDGDDGINAEVRYT 1108 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP-SRSNTTQLLINIRD 249 ++G + F I+ +G V+LV +LD E Y+L + A+D G P S +N+T +LI + D Sbjct: 1109 LMG--EESLFRINYTTGIVTLVSSLDRENKAQYQLEVEARDRGIPESNANSTTILIRVGD 1166 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 VNDN P F + + +V E +G V A D DE +NA++ Y++ GN D Sbjct: 1167 VNDNRPTFTHAHYDGNVLEG-QVGAVAAIVVALDKDEEINADIVYSIIG----GNTDNSF 1221 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 I+ +SG +YT LDRET +Y L V A+D G+P +++ Sbjct: 1222 AINNKSGSIYTLLHLDRETTDRYILTVLASDRGEPAMNSSTNVTIHVNDVNDNKPNITNN 1281 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITG-GNTRGRFSITSQNGRGLITVAQP 428 V E+ PPG+ V L+A+D DE + +G G+FSI NG I V Sbjct: 1282 PGVVVTRENTPPGSLVYILSASDLDEGSNARVAFSGYAVPDGKFSI-KPNGE--IMVRDS 1338 Query: 429 LDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 LD + + R+V ATDSG S I I D N+ PVF+ Y+ ++ E+ P Sbjct: 1339 LDREAQNRFVFYAMATDSGQPPFNSSMVSFDILIADENDNNPVFDPVHYSVNISENGPSE 1398 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 ++ V+A++ D G ++ + +SS F I+ TG I+T K LDRE +S Sbjct: 1399 EVIVQVNASERDEG---KLLFKISS-------GDPGGYFTIHNVTGVISTRKPLDREMVS 1448 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 + LT+TA D G PS V I V D ND PV +Q ++ E+A +G++V+ + A Sbjct: 1449 RFDLTITAEDEGRPSRMALGYVTIFVNDENDFAPVIEQCEQLVSVSENAHIGSAVASINA 1508 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASG-----VIRTNKALDRESVATHDLKAVAI 660 D D N +I Y + + + +SG +I T LDRE +++ A Sbjct: 1509 VDKDDPSNTKITYSVGNSAFNITTQRLPFSSGSRYRGIIITAGLLDRERQDNYNITVTAS 1568 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700 DG +T + ++I D+ND+ PVF + + E S Sbjct: 1569 DGN---HIATCNIIVRITDVNDNSPVFNQTTMNISLHEVS 1605 Score = 279 bits (684), Expect = 8e-73 Identities = 226/744 (30%), Positives = 348/744 (46%), Gaps = 53/744 (7%) Query: 161 EDISVTDNPVIAKIKATDADVGA-NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQ 219 E T + + ATD D N + YAI+ GN F ID G + L + LD+EQ Sbjct: 118 ETCKSTSGLSVLTMSATDMDAEEINQRVNYAIVSGNEDGIFDIDFNKGVIRLARELDFEQ 177 Query: 220 VRSYRLVIRAQ-----DGGSPSR--SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI 272 + Y+L I A D P SN T + +N+ D +D RF + S+ EN + Sbjct: 178 MTQYKLNISASNPLTNDTVIPKNGLSNWTMVTVNVLDADDLPVRFNNYSYSASIPENAAM 237 Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332 G +++V A D D+ +NA +TY + DK+ T + + I +G + +G LDRET A+Y Sbjct: 238 GSVVMQVHAKDLDKSINAPVTYAI-DKE-TNPLRM-FNIANITGEITLNGSLDRETIAEY 294 Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392 +L + A + T +P Y + E+ GT V+ + A D Sbjct: 295 RLRILAYC--TIYQDHTEVLITVTDVNDNIPLFTLPS-YNTTVNENAAIGTYVIQVQAED 351 Query: 393 ADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD---SGGR 449 D+ + F I +G +I V LD +++ Y +TV A + S G Sbjct: 352 IDQGVNASFIYEIAYAGHEFVIGEHSG--IIIVNGTLDREKKDLYSITVIARETETSAGF 409 Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509 + + + D N+ +P+F A Y++ ++E+ P GT V+ VSA DSD+G NA ++Y++ Sbjct: 410 HSNVTITVMLRDENDNSPIFSRALYSSPIYENEPPGTFVIQVSANDSDIGSNAMVSYAVL 469 Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL--SDTTDV 567 S+ H Q F IN + G ITT++ LDRE ++ + L VTA DG S DV Sbjct: 470 SDAEG-----HYQYFKINAKNGTITTSRRLDRENITTFRLRVTASDGAPLSTIRVSVVDV 524 Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627 ++V+D+NDN P F + Y +++E AL G + + A D D LNG I Y + + E Sbjct: 525 VVTVLDINDNSPEFVRPSYNFSVIETALPGAILGIISAVDRDKDLNGNIVY-IITEGNVE 583 Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG------TPPQSSTVIVHIKIEDIN 681 GSF+I SG+++ N LDRE V+ H L+ A D G ++T+ V I + D N Sbjct: 584 GSFIIGARSGLLQLNHTLDREVVSKHSLRVTASDRGGEFMADGSSLNTTINVTINVLDSN 643 Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741 D+ PV + T I EN+ +G ++ + D D G NA + Y + G + F ++ Sbjct: 644 DNIPVCDKVYYTISIPENTSVGQSLIHLNCTDQDSGENAHLLYHMVSG--HSKFVVDNVT 701 Query: 742 GSDKAELVTMVDLDYESPRKKYEL---VIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQ 798 G + LD+E + + VI PPL V V + V +VNDN P Sbjct: 702 GIMSLNKL----LDFEEKPTVFTVAIEVIDHGRPPLSLVVFVNVTVDNVNDNYPSFGQDN 757 Query: 799 IIFNNYKDCFPV--GPFGRVPAYDAD-------VTDKLQYRILSGNNANLILLNETTGSM 849 F + F V G V A+D D + KLQY + GN+ +++ TG + Sbjct: 758 YTFWISEGDFAVDHAIVGVVSAHDLDADSSNCPLCGKLQYTL--GNSTGPFAIDKDTGVL 815 Query: 850 TLSPQLNTNVPKLATMEVSVTDGV 873 L+ K T V D + Sbjct: 816 RAVGSLDREGIKNYTFSVIAQDSI 839 Score = 274 bits (671), Expect = 3e-71 Identities = 200/599 (33%), Positives = 295/599 (49%), Gaps = 46/599 (7%) Query: 1 MSVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEY 60 M V +H + V+D NDH+P F M +Y S E G+T+ ++A D D G NAEV Y Sbjct: 1050 MEVNCSVH--VIVMDTNDHTPSFTMARYYISTPETTPVGSTLFRVRAVDGDDGINAEVRY 1107 Query: 61 TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT 120 T+ + +FRI+ +G + +SLDRE A+Y + V+A Sbjct: 1108 TL---------------------MGEESLFRINYTTGIVTLVSSLDRENKAQYQLEVEAR 1146 Query: 121 DQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD 180 D+ P S+ S+T I V D NDN P F+ Y +V E V A + A D D Sbjct: 1147 DRGIPESNANSTTILIRVG--DVNDNRPTFTHAHYDGNVLEG---QVGAVAAIVVALDKD 1201 Query: 181 VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240 N+ I Y+IIGGNT F+I++ SG + + LD E Y L + A D G P+ +++ Sbjct: 1202 EEINADIVYSIIGGNTDNSFAINNKSGSIYTLLHLDRETTDRYILTVLASDRGEPAMNSS 1261 Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 T + I++ DVNDN P + EN P G + + A D DEG NA + ++ Sbjct: 1262 TNVTIHVNDVNDNKPNITNNPGVVVTRENTPPGSLVYILSASDLDEGSNARVAFS----G 1317 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP-RSATATXXXXXXXX 359 Y D +I P +G + LDRE Q ++ ATD G PP S+ + Sbjct: 1318 Y-AVPDGKFSIKP-NGEIMVRDSLDREAQNRFVFYAMATDSGQPPFNSSMVSFDILIADE 1375 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG 419 F P Y V ++E+ P +V + A++ DE +L ++I+ G+ G F+I N Sbjct: 1376 NDNNPVFDPVHYSVNISENGPSEEVIVQVNASERDE-GKLLFKISSGDPGGYFTI--HNV 1432 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTAS 477 G+I+ +PLD + R+ LT++A D G S A+ V I + D N++APV E S Sbjct: 1433 TGVISTRKPLDREMVSRFDLTITAEDEGRPSRMALGYVTIFVNDENDFAPVIEQCEQLVS 1492 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ-TGAITTN 536 V E+A IG+ V ++A D D N +ITYS+ + N + F + G I T Sbjct: 1493 VSENAHIGSAVASINAVDKDDPSNTKITYSVGNSAFN--ITTQRLPFSSGSRYRGIIITA 1550 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 LLDRE Y +TVTA DG + T ++ + + DVNDN PVF Q ++ E +L Sbjct: 1551 GLLDRERQDNYNITVTASDGNHIA---TCNIIVRITDVNDNSPVFNQTTMNISLHEVSL 1606 Score = 217 bits (529), Expect = 5e-54 Identities = 164/519 (31%), Positives = 255/519 (49%), Gaps = 41/519 (7%) Query: 382 GTPVVTLTATDADEDN---RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYV 438 G V+T++ATD D + R++Y I GN G F I +G+I +A+ LDF+Q +Y Sbjct: 125 GLSVLTMSATDMDAEEINQRVNYAIVSGNEDGIFDIDFN--KGVIRLARELDFEQMTQYK 182 Query: 439 LTVSATD---------SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 L +SA++ G S+ MV +N+ DA++ F N Y+AS+ E+A +G+ V+ Sbjct: 183 LNISASNPLTNDTVIPKNGLSNWTMVTVNVLDADDLPVRFNNYSYSASIPENAAMGSVVM 242 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 V A D D INA +TY++ E +N + F I TG IT N LDRET++ Y L Sbjct: 243 QVHAKDLDKSINAPVTYAIDKE-TNPL-----RMFNIANITGEITLNGSLDRETIAEYRL 296 Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 + A D T+V I+V DVNDN P+F Y + E+A +GT V QV A D D Sbjct: 297 RILAY---CTIYQDHTEVLITVTDVNDNIPLFTLPSYNTTVNENAAIGTYVIQVQAEDID 353 Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ-S 668 G+N YE+ E FVI SG+I N LDRE + + +A + T Sbjct: 354 QGVNASFIYEIAYAGHE---FVIGEHSGIIIVNGTLDREKKDLYSITVIARETETSAGFH 410 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 S V + + + D ND+ P+F + I EN P GT + ++ A+D D G NA+V Y++ Sbjct: 411 SNVTITVMLRDENDNSPIFSRALYSSPIYENEPPGTFVIQVSANDSDIGSNAMVSYAVLS 470 Query: 729 GDDSNS--FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEIL--- 783 + + F + + G+ + T LD E+ + L + A+ + +RV ++ Sbjct: 471 DAEGHYQYFKINAKNGT----ITTSRRLDRENITT-FRLRVTASDGAPLSTIRVSVVDVV 525 Query: 784 --VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANL 839 V D+NDN+P F+ + P G + A D D + + Y I GN Sbjct: 526 VTVLDINDNSPEFVRPSYNFSVIETALPGAILGIISAVDRDKDLNGNIVYIITEGNVEGS 585 Query: 840 ILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKA 878 ++ +G + L+ L+ V ++ V+ +D E A Sbjct: 586 FIIGARSGLLQLNHTLDREVVSKHSLRVTASDRGGEFMA 624 Score = 131 bits (317), Expect = 2e-28 Identities = 135/482 (28%), Positives = 232/482 (48%), Gaps = 47/482 (9%) Query: 485 GTTVLVVSATDSDVG-INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 G +VL +SATD D IN ++ Y++ S NE D F I+ G I + LD E Sbjct: 125 GLSVLTMSATDMDAEEINQRVNYAIVS--GNE-----DGIFDIDFNKGVIRLARELDFEQ 177 Query: 544 MSGYLLTVTA-----RDGGVPS--LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 M+ Y L ++A D +P LS+ T V ++V+D +D F Y+A+I E+A + Sbjct: 178 MTQYKLNISASNPLTNDTVIPKNGLSNWTMVTVNVLDADDLPVRFNNYSYSASIPENAAM 237 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 G+ V QV A D D +N + Y +D + F I +G I N +LDRE++A + L+ Sbjct: 238 GSVVMQVHAKDLDKSINAPVTYAIDKETNPLRMFNIANITGEITLNGSLDRETIAEYRLR 297 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 +A T Q T ++ I + D+ND+ P+F ++EN+ IGT + +++A D D+ Sbjct: 298 ILAY--CTIYQDHTEVL-ITVTDVNDNIPLFTLPSYNTTVNENAAIGTYVIQVQAEDIDQ 354 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA----ASP 772 G NA Y I + F + G ++ LD E + Y + + A S Sbjct: 355 GVNASFIYEIAYA--GHEFVI----GEHSGIIIVNGTLDREK-KDLYSITVIARETETSA 407 Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVTDK--LQY 829 ++V + +++ D NDN+P+ Y++ P G F +V A D+D+ + Y Sbjct: 408 GFHSNVTITVMLRDENDNSPIFSRALYSSPIYEN-EPPGTFVIQVSANDSDIGSNAMVSY 466 Query: 830 RILSG--NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887 +LS + +N G++T S +L+ + V+ +DG A + ++R+ Sbjct: 467 AVLSDAEGHYQYFKINAKNGTITTSRRLDRENITTFRLRVTASDG-----APLS-TIRVS 520 Query: 888 TEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNIL 947 ++++ + + ND + E F+ P F + + +P I I +V D D+ GNI+ Sbjct: 521 VVDVVVTVLDI--NDNSPE-FVRPSYNFSV--IETALPGAILGI-ISAVDRDKDLNGNIV 574 Query: 948 NV 949 + Sbjct: 575 YI 576 >UniRef50_UPI00006610B3 Cluster: Homolog of Brachydanio rerio "Cadherin-related neuronal receptor variable 9.; n=1; Takifugu rubripes|Rep: Homolog of Brachydanio rerio "Cadherin-related neuronal receptor variable 9. - Takifugu rubripes Length = 1254 Score = 327 bits (803), Expect = 3e-87 Identities = 262/908 (28%), Positives = 413/908 (45%), Gaps = 62/908 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +INV+D ND+ P+F Y+ V E A+ G T+LTL ATD D G N E+ Y+ Sbjct: 9 RINVIDVNDNYPLFSKSLYKVQVVENANVGATILTLSATDLDDGVNGELVYSF--AERGR 66 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 NPED F ++ +G + + ++D E+ Y + V+A D+ +P Sbjct: 67 FNPEDK--------------FALNAHNGEITLKGNIDYEENPAYEIRVQARDKGAPPR-- 110 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 ++ + + V +ID NDN P+ S + V ED + +A + D D G N Sbjct: 111 -TAHSKVLVEVIDVNDNAPEISVSSLMSPVKEDAGL--GTAVAMVTINDRDGGKNGLTNC 167 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I G M S + + LD E Y + I A+D G+PS + TT + + I D Sbjct: 168 RITGSVPFMLKSNYKNYYSLVVDGPLDRETASQYNVTITAEDEGTPSLTGTTIINVQISD 227 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 VNDN PRF SL + EN P+G ++ R+ D+D NA+ TY + + V I Sbjct: 228 VNDNPPRFPDSLLNVYLKENSPVGSTVHRLTTLDSDLNENAKATYHLLNNSPKSGVAAMI 287 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 I+ +G + + + E +Q V ATD G PP S+ T + Sbjct: 288 NINSETGDIISLQSFNYEELKTFQFKVQATDSGVPPLSSNVTVNVFILDENDNSPTILAP 347 Query: 370 QYEVELAEDE------PPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRG 421 E E G V + A DAD + L Y ++ F + + G Sbjct: 348 YSEHGSVNSESIPYSAEAGYFVAKIRAVDADSGYNALLSYHLSEPKGNNLFRMGTSTGE- 406 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV---FENAPYTASV 478 I + + + + L V +D+G S +A V I + + A + F + P Sbjct: 407 -IRTKRRMSDNDLKTHPLVVLVSDNGDPSLSATVSIEVVVVESAADIQTQFRHVPMKEES 465 Query: 479 FEDAPIGTTVLVVSATD---SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 F D + + +VS + + G N+ Y +S +NE + D + + + Sbjct: 466 FSDLNLYLLIAIVSVSAIFLLNTGSNSVKAYKIS---ANEHFS-VDVSSGADGTSAELVL 521 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 K LDRE + LT+TA DGG P+ S T + ++V+DVNDN PVF Q LY + E Sbjct: 522 EKALDREKQALIKLTLTAVDGGKPARSGTLQILVNVIDVNDNTPVFSQSLYKVRVSEGVP 581 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDR-EEGSFVIDPASGVIRTNKALDRESVATHD 654 VGT + ++ A D D G NG + Y L + F +DP SG I +LD E ++ Sbjct: 582 VGTQILKLNANDLDEGSNGDLRYSLMKRGNVNSEKFSVDPESGEIVVKASLDYEESGAYE 641 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 L+ A D G P+S V +++ D+ND+ P L I E++ +GT + + D Sbjct: 642 LRVQATDQGASPRSGYSKVLVEVLDVNDNAPEISVTSLMSPIKESAGLGTVVALVSVTDK 701 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---AS 771 D G N + I+ DS+ F+L++ S + +V + LD E+ +Y++ I A + Sbjct: 702 DGGQNGHLSCKIR---DSSPFALKSNYKSYYSLVVDGL-LDRET-ISQYDVTIVATDEGT 756 Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY-KDCFPVGP-FGRVPAYDADVTD--KL 827 PPL + + + ++DVNDNAP D + N Y K+ VG R A DADV D KL Sbjct: 757 PPLSSTAVISVQISDVNDNAPRFMDENL--NIYIKENSRVGDIITRASAQDADVNDNAKL 814 Query: 828 QYRILSGNNANLIL-----LNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQ 881 Y +L + ++++ +N TG + N K +V TD GV + + + Sbjct: 815 TYSLLDSHQKDVLISTVVNINSATGDIISLQSFNYEELKTFQFKVQATDSGVPPLSSNVT 874 Query: 882 LSVRLITE 889 ++V ++ E Sbjct: 875 VNVFILDE 882 Score = 293 bits (718), Expect = 6e-77 Identities = 226/828 (27%), Positives = 393/828 (47%), Gaps = 60/828 (7%) Query: 98 ALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTV 157 +L+ LDRE ++Y V + A D+ +P L+ T I+V I D NDN P+F + V Sbjct: 186 SLVVDGPLDRETASQYNVTITAEDEGTP---SLTGTTIINVQISDVNDNPPRFPDSLLNV 242 Query: 158 SVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQM----QFSIDSLSGDVSLVK 213 + E+ V + ++ D+D+ N+ Y ++ + + +I+S +GD+ ++ Sbjct: 243 YLKENSPV--GSTVHRLTTLDSDLNENAKATYHLLNNSPKSGVAAMININSETGDIISLQ 300 Query: 214 TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF------YTSLFQESVS 267 + +YE++++++ ++A D G P S+ + + I D NDN+P + S+ ES+ Sbjct: 301 SFNYEELKTFQFKVQATDSGVPPLSSNVTVNVFILDENDNSPTILAPYSEHGSVNSESIP 360 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 + GY + +++A DAD G NA L+Y +++ GN +L + +G + T ++ Sbjct: 361 YSAEAGYFVAKIRAVDADSGYNALLSYHLSEPK--GN-NL-FRMGTSTGEIRTKRRMSDN 416 Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX---FMPGQYEVELAEDEPPGTP 384 + L+V +D GDP SAT + +P + E + Sbjct: 417 DLKTHPLVVLVSDNGDPSLSATVSIEVVVVESAADIQTQFRHVPMKEESFSDLNLYLLIA 476 Query: 385 VVTLTAT---DADEDNRLHYEITGGNTRGRFSITSQNGR----GLITVAQPLDFKQERRY 437 +V+++A + ++ Y+I+ FS+ +G + + + LD +++ Sbjct: 477 IVSVSAIFLLNTGSNSVKAYKISANE---HFSVDVSSGADGTSAELVLEKALDREKQALI 533 Query: 438 VLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495 LT++A D G RS T + +N+ D N+ PVF + Y V E P+GT +L ++A D Sbjct: 534 KLTLTAVDGGKPARSGTLQILVNVIDVNDNTPVFSQSLYKVRVSEGVPVGTQILKLNAND 593 Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555 D G N + YSL N + ++F ++P++G I LD E Y L V A D Sbjct: 594 LDEGSNGDLRYSLMKR-GNV----NSEKFSVDPESGEIVVKASLDYEESGAYELRVQATD 648 Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615 G S + V + V+DVNDN P + I E A +GT V+ V TD D G NG Sbjct: 649 QGASPRSGYSKVLVEVLDVNDNAPEISVTSLMSPIKESAGLGTVVALVSVTDKDGGQNGH 708 Query: 616 IHYELDPKDREEGSFVIDP---ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672 L K R+ F + + + + LDRE+++ +D+ VA D GTPP SST + Sbjct: 709 ----LSCKIRDSSPFALKSNYKSYYSLVVDGLLDRETISQYDVTIVATDEGTPPLSSTAV 764 Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732 + ++I D+ND+ P F + L YI ENS +G I A D D NA + YS+ Sbjct: 765 ISVQISDVNDNAPRFMDENLNIYIKENSRVGDIITRASAQDADVNDNAKLTYSLLDSHQK 824 Query: 733 NSF-SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVN 788 + S S +++++ +YE K ++ ++A PPL ++V V + + D N Sbjct: 825 DVLISTVVNINSATGDIISLQSFNYEE-LKTFQFKVQATDSGVPPLSSNVTVNVFILDEN 883 Query: 789 DNAP-VMKDFQIIFNNYKDCFP----VGPF-GRVPAYDAD--VTDKLQYRILSGNNANLI 840 DN+P ++ + + + P G F ++ A DAD L Y + NL Sbjct: 884 DNSPTILAPYSEHGSVNSESIPYSAEAGYFVAKIRAVDADSGYNALLSYHLSEPKGNNLF 943 Query: 841 LLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLI 887 + +TG + +++ N K + V V+D G + A + + V ++ Sbjct: 944 RMGTSTGEIRTKRRMSDNDLKTHPLVVLVSDNGDPSLSATVSIEVVVV 991 Score = 280 bits (686), Expect = 5e-73 Identities = 220/725 (30%), Positives = 336/725 (46%), Gaps = 47/725 (6%) Query: 93 DGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSE 152 DG S L+ +LDREK A + + A D P S T I VN+ID NDN P FS+ Sbjct: 513 DGTSAELVLEKALDREKQALIKLTLTAVDGGKPAR---SGTLQILVNVIDVNDNTPVFSQ 569 Query: 153 KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG-GNTQMQ-FSIDSLSGDVS 210 Y V V E + V I K+ A D D G+N +RY+++ GN + FS+D SG++ Sbjct: 570 SLYKVRVSEGVPVGTQ--ILKLNANDLDEGSNGDLRYSLMKRGNVNSEKFSVDPESGEIV 627 Query: 211 LVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENV 270 + +LDYE+ +Y L ++A D G+ RS +++L+ + DVNDNAP + + E+ Sbjct: 628 VKASLDYEESGAYELRVQATDQGASPRSGYSKVLVEVLDVNDNAPEISVTSLMSPIKESA 687 Query: 271 PIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW-VYTSGQLDRETQ 329 +G + V D D G N L+ + D + + +S + + G LDRET Sbjct: 688 GLGTVVALVSVTDKDGGQNGHLSCKIRDSS-----PFALKSNYKSYYSLVVDGLLDRETI 742 Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389 ++Y + + ATD G PP S+TA FM + + E+ G + + Sbjct: 743 SQYDVTIVATDEGTPPLSSTAVISVQISDVNDNAPRFMDENLNIYIKENSRVGDIITRAS 802 Query: 390 ATDAD-EDN-RLHYEITGGNTRGRFSITSQN---GRGLITVAQPLDFKQERRYVLTVSAT 444 A DAD DN +L Y + + + T N G I Q ++++ + + V AT Sbjct: 803 AQDADVNDNAKLTYSLLDSHQKDVLISTVVNINSATGDIISLQSFNYEELKTFQFKVQAT 862 Query: 445 DSG--GRSDTAMVQINITDANNYAPVFENAPYTA-------SVFEDAPIGTTVLVVSATD 495 DSG S V + I D N+ +P APY+ S+ A G V + A D Sbjct: 863 DSGVPPLSSNVTVNVFILDENDNSPTIL-APYSEHGSVNSESIPYSAEAGYFVAKIRAVD 921 Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555 +D G NA ++Y LS N F + TG I T + + + + L V D Sbjct: 922 ADSGYNALLSYHLSEPKGNNL-------FRMGTSTGEIRTKRRMSDNDLKTHPLVVLVSD 974 Query: 556 GGVPSLSDTTDVEISVVD-VNDNEPVFKQQLYTANIMEDALVGTSVSQV-GATDADVGLN 613 G PSLS T +E+ VV+ D + F+ D + ++ V ATD D G N Sbjct: 975 NGDPSLSATVSIEVVVVESAADIQTQFRHVPMKEESFSDLNLYLLIAIVLNATDLDEGQN 1034 Query: 614 GRIHYELDPKDREEGSFVIDPAS--GVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671 G+I Y + + S + D S G I+ LD E ++++ A D GT P+S+ Sbjct: 1035 GKIKYSFIKRGNSDPSNIFDLNSDTGEIKVKGELDYEETPAYEVRVQANDQGTTPRSAHA 1094 Query: 672 IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD 731 + I+I D ND+ P L + E++ +GT + I +D D G N V + G Sbjct: 1095 KLLIEIIDENDNAPEISVTSLMTPLKEDAELGTIVALITVNDKDGGKNGVAVCKVVG--- 1151 Query: 732 SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVN 788 S F L++ ++ LV LD E+ Y + ++A PPL + + ++DVN Sbjct: 1152 SVPFKLKSNY-KNEYSLVVDGALDREN-TSVYNVTVQATDEGDPPLSTIKVITVHISDVN 1209 Query: 789 DNAPV 793 DNAPV Sbjct: 1210 DNAPV 1214 Score = 272 bits (667), Expect = 9e-71 Identities = 211/692 (30%), Positives = 328/692 (47%), Gaps = 52/692 (7%) Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S I +N+ID NDNYP FS+ Y V V E+ +V I + ATD D G N + Y+ Sbjct: 3 SGNLQIRINVIDVNDNYPLFSKSLYKVQVVENANV--GATILTLSATDLDDGVNGELVYS 60 Query: 191 IIGG---NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 N + +F++++ +G+++L +DYE+ +Y + ++A+D G+P R+ +++L+ + Sbjct: 61 FAERGRFNPEDKFALNAHNGEITLKGNIDYEENPAYEIRVQARDKGAPPRTAHSKVLVEV 120 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 DVNDNAP S V E+ +G ++ V D D G N +T+ TG+V Sbjct: 121 IDVNDNAPEISVSSLMSPVKEDAGLGTAVAMVTINDRDGGKNG-----LTNCRITGSVPF 175 Query: 308 PITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 + + ++ + + G LDRET ++Y + +TA D G P + T F Sbjct: 176 MLKSNYKNYYSLVVDGPLDRETASQYNVTITAEDEGTPSLTGTTIINVQISDVNDNPPRF 235 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFS--ITSQNGRGL 422 V L E+ P G+ V LT D+D E+ + Y + + + + I + G Sbjct: 236 PDSLLNVYLKENSPVGSTVHRLTTLDSDLNENAKATYHLLNNSPKSGVAAMININSETGD 295 Query: 423 ITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPY------ 474 I Q ++++ + + V ATDSG S V + I D N+ +P APY Sbjct: 296 IISLQSFNYEELKTFQFKVQATDSGVPPLSSNVTVNVFILDENDNSPTI-LAPYSEHGSV 354 Query: 475 -TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 + S+ A G V + A D+D G NA ++Y LS N F + TG I Sbjct: 355 NSESIPYSAEAGYFVAKIRAVDADSGYNALLSYHLSEPKGNNL-------FRMGTSTGEI 407 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD-VNDNEPVFKQQLYTANIME 592 T + + + + L V D G PSLS T +E+ VV+ D + F+ Sbjct: 408 RTKRRMSDNDLKTHPLVVLVSDNGDPSLSATVSIEVVVVESAADIQTQFRHVPMKEESFS 467 Query: 593 DA---LVGTSVSQVGATDADVGLNGRIHYELDPKDR--EEGSFVIDPASGVIRTNKALDR 647 D L+ VS + G N Y++ + + S D S + KALDR Sbjct: 468 DLNLYLLIAIVSVSAIFLLNTGSNSVKAYKISANEHFSVDVSSGADGTSAELVLEKALDR 527 Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 E A L A+DGG P +S T+ + + + D+ND+ PVF +SE P+GT I Sbjct: 528 EKQALIKLTLTAVDGGKPARSGTLQILVNVIDVNDNTPVFSQSLYKVRVSEGVPVGTQIL 587 Query: 708 EIRAHDPDEGPNAVVHYSI--KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765 ++ A+D DEG N + YS+ +G +S FS++ G E+V LDYE YEL Sbjct: 588 KLNANDLDEGSNGDLRYSLMKRGNVNSEKFSVDPESG----EIVVKASLDYEE-SGAYEL 642 Query: 766 VIRA----ASPPL-WNDVRVEILVTDVNDNAP 792 ++A ASP ++ V VE+L DVNDNAP Sbjct: 643 RVQATDQGASPRSGYSKVLVEVL--DVNDNAP 672 Score = 269 bits (659), Expect = 9e-70 Identities = 218/740 (29%), Positives = 326/740 (44%), Gaps = 64/740 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NV+D ND++PVF Y+ V EG GT +L L A D D G N ++ Y+ L+ + Sbjct: 555 VNVIDVNDNTPVFSQSLYKVRVSEGVPVGTQILKLNANDLDEGSNGDLRYS--LMKRGNV 612 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N E F +D SG ++ +ASLD E+ Y + V+ATDQ + S R Sbjct: 613 NSEK---------------FSVDPESGEIVVKASLDYEESGAYELRVQATDQGA--SPR- 654 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S + + V ++D NDN P+ S + + E + V+A + TD D G N + Sbjct: 655 SGYSKVLVEVLDVNDNAPEISVTSLMSPIKESAGL--GTVVALVSVTDKDGGQNGHLSCK 712 Query: 191 IIGGNTQMQFSIDS-LSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 I F++ S SLV LD E + Y + I A D G+P S+T + + I Sbjct: 713 I---RDSSPFALKSNYKSYYSLVVDGLLDRETISQYDVTIVATDEGTPPLSSTAVISVQI 769 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN-VD 306 DVNDNAPRF + EN +G I R A DAD NA+LTY++ D + Sbjct: 770 SDVNDNAPRFMDENLNIYIKENSRVGDIITRASAQDADVNDNAKLTYSLLDSHQKDVLIS 829 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 + I+ +G + + + E +Q V ATD G PP S+ T Sbjct: 830 TVVNINSATGDIISLQSFNYEELKTFQFKVQATDSGVPPLSSNVTVNVFILDENDNSPTI 889 Query: 367 MPGQYEVELAEDEP------PGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQN 418 + E E G V + A DAD L Y ++ F + + Sbjct: 890 LAPYSEHGSVNSESIPYSAEAGYFVAKIRAVDADSGYNALLSYHLSEPKGNNLFRMGTST 949 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV---FENAPYT 475 G I + + + + L V +D+G S +A V I + + A + F + P Sbjct: 950 GE--IRTKRRMSDNDLKTHPLVVLVSDNGDPSLSATVSIEVVVVESAADIQTQFRHVPMK 1007 Query: 476 ASVFEDAPIGTTV-LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 F D + + +V++ATD D G N +I YS +++ F +N TG I Sbjct: 1008 EESFSDLNLYLLIAIVLNATDLDEGQNGKIKYSFIKRGNSDP----SNIFDLNSDTGEIK 1063 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 LD E Y + V A D G S + I ++D NDN P + EDA Sbjct: 1064 VKGELDYEETPAYEVRVQANDQGTTPRSAHAKLLIEIIDENDNAPEISVTSLMTPLKEDA 1123 Query: 595 LVGTSVSQVGATDADVGLNG--------RIHYELDPKDREEGSFVIDPASGVIRTNKALD 646 +GT V+ + D D G NG + ++L + E S V+D A LD Sbjct: 1124 ELGTIVALITVNDKDGGKNGVAVCKVVGSVPFKLKSNYKNEYSLVVDGA---------LD 1174 Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706 RE+ + +++ A D G PP S+ ++ + I D+ND+ PVF + Y+ ENS G+ I Sbjct: 1175 RENTSVYNVTVQATDEGDPPLSTIKVITVHISDVNDNAPVFMVPVINVYLRENSQTGSVI 1234 Query: 707 GEIRAHDPDEGPNAVVHYSI 726 I A DPD NA V Y++ Sbjct: 1235 DTISAVDPDLDHNAKVIYTL 1254 Score = 264 bits (647), Expect = 2e-68 Identities = 228/808 (28%), Positives = 357/808 (44%), Gaps = 61/808 (7%) Query: 13 VLDCNDHSPVFEMQQYE------ASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 +LD ND+SP E S+ A +G V ++A D D G NA + Y + Sbjct: 334 ILDENDNSPTILAPYSEHGSVNSESIPYSAEAGYFVAKIRAVDADSGYNALLSYHLS--- 390 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 P+ ++FR+ +G + T+ + + + ++V +D P Sbjct: 391 ----EPKG------------NNLFRMGTSTGEIRTKRRMSDNDLKTHPLVVLVSDNGDP- 433 Query: 127 SDRLSSTATIHVNIIDDN-DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA-DVGAN 184 LS+T +I V +++ D QF D+++ I + A + G+N Sbjct: 434 --SLSATVSIEVVVVESAADIQTQFRHVPMKEESFSDLNLYLLIAIVSVSAIFLLNTGSN 491 Query: 185 SAIRYAIIGG---NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 S Y I + + D S ++ L K LD E+ +L + A DGG P+RS T Sbjct: 492 SVKAYKISANEHFSVDVSSGADGTSAELVLEKALDREKQALIKLTLTAVDGGKPARSGTL 551 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 Q+L+N+ DVNDN P F SL++ VSE VP+G I+++ A D DEG N +L Y++ + Sbjct: 552 QILVNVIDVNDNTPVFSQSLYKVRVSEGVPVGTQILKLNANDLDEGSNGDLRYSLMKR-- 609 Query: 302 TGNVDL-PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 GNV+ ++DP SG + LD E Y+L V ATD G PRS + Sbjct: 610 -GNVNSEKFSVDPESGEIVVKASLDYEESGAYELRVQATDQGASPRSGYSKVLVEVLDVN 668 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420 + E GT V ++ TD D H ++ ++ Sbjct: 669 DNAPEISVTSLMSPIKESAGLGTVVALVSVTDKDGGQNGHLSCKIRDSSPFALKSNYKSY 728 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASV 478 + V LD + +Y +T+ ATD G S TA++ + I+D N+ AP F + + Sbjct: 729 YSLVVDGLLDRETISQYDVTIVATDEGTPPLSSTAVISVQISDVNDNAPRFMDENLNIYI 788 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 E++ +G + SA D+DV NA++TYSL + + IN TG I + + Sbjct: 789 KENSRVGDIITRASAQDADVNDNAKLTYSLLDSHQKDVLI--STVVNINSATGDIISLQS 846 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF------KQQLYTANIME 592 + E + + V A D GVP LS V + ++D NDN P + + +I Sbjct: 847 FNYEELKTFQFKVQATDSGVPPLSSNVTVNVFILDENDNSPTILAPYSEHGSVNSESIPY 906 Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652 A G V+++ A DAD G N + Y L + + F + ++G IRT + + + T Sbjct: 907 SAEAGYFVAKIRAVDADSGYNALLSYHLS-EPKGNNLFRMGTSTGEIRTKRRMSDNDLKT 965 Query: 653 HDLKAVAIDGGTPPQSSTVIVH-IKIEDINDSPPVFESDCLTFYISENSPIGTTIG-EIR 710 H L + D G P S+TV + + +E D F + + + I + Sbjct: 966 HPLVVLVSDNGDPSLSATVSIEVVVVESAADIQTQFRHVPMKEESFSDLNLYLLIAIVLN 1025 Query: 711 AHDPDEGPNAVVHYS-IKGG--DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 A D DEG N + YS IK G D SN F L SD E+ +LDYE YE+ + Sbjct: 1026 ATDLDEGQNGKIKYSFIKRGNSDPSNIFDL----NSDTGEIKVKGELDYEE-TPAYEVRV 1080 Query: 768 RA---ASPPLWNDVRVEILVTDVNDNAP 792 +A + P ++ I + D NDNAP Sbjct: 1081 QANDQGTTPRSAHAKLLIEIIDENDNAP 1108 Score = 206 bits (504), Expect = 5e-51 Identities = 179/658 (27%), Positives = 291/658 (44%), Gaps = 34/658 (5%) Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 +S Q+ IN+ DVNDN P F SL++ V EN +G +I+ + A D D+GVN EL Y+ Sbjct: 2 KSGNLQIRINVIDVNDNYPLFSKSLYKVQVVENANVGATILTLSATDLDDGVNGELVYSF 61 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 ++ N + ++ +G + G +D E Y++ V A D G PPR+A + Sbjct: 62 AERG-RFNPEDKFALNAHNGEITLKGNIDYEENPAYEIRVQARDKGAPPRTAHSKVLVEV 120 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSI 414 + ED GT V +T D D ++ + IT G+ Sbjct: 121 IDVNDNAPEISVSSLMSPVKEDAGLGTAVAMVTINDRDGGKNGLTNCRIT-GSVPFMLKS 179 Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENA 472 +N L+ V PLD + +Y +T++A D G S T ++ + I+D N+ P F ++ Sbjct: 180 NYKNYYSLV-VDGPLDRETASQYNVTITAEDEGTPSLTGTTIINVQISDVNDNPPRFPDS 238 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 + E++P+G+TV ++ DSD+ NA+ TY L + VA IN +TG Sbjct: 239 LLNVYLKENSPVGSTVHRLTTLDSDLNENAKATYHLLNNSPKSGVA---AMININSETGD 295 Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF------KQQLY 586 I + + + E + + V A D GVP LS V + ++D NDN P + Sbjct: 296 IISLQSFNYEELKTFQFKVQATDSGVPPLSSNVTVNVFILDENDNSPTILAPYSEHGSVN 355 Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646 + +I A G V+++ A DAD G N + Y L + + F + ++G IRT + + Sbjct: 356 SESIPYSAEAGYFVAKIRAVDADSGYNALLSYHLS-EPKGNNLFRMGTSTGEIRTKRRMS 414 Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVH-IKIEDINDSPPVFESDCL--TFYISENSPIG 703 + TH L + D G P S+TV + + +E D F + + N + Sbjct: 415 DNDLKTHPLVVLVSDNGDPSLSATVSIEVVVVESAADIQTQFRHVPMKEESFSDLNLYLL 474 Query: 704 TTIGEIRA-HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD--KAELVTMVDLDYESPR 760 I + A + G N+V Y I + FS++ G+D AELV LD E Sbjct: 475 IAIVSVSAIFLLNTGSNSVKAYKISANE---HFSVDVSSGADGTSAELVLEKALDREKQA 531 Query: 761 --KKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVP 817 K + P +++ + V DVNDN PV + + PVG ++ Sbjct: 532 LIKLTLTAVDGGKPARSGTLQILVNVIDVNDNTPVFSQ-SLYKVRVSEGVPVGTQILKLN 590 Query: 818 AYDAD--VTDKLQYRILS-GN-NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 A D D L+Y ++ GN N+ ++ +G + + L+ + V TD Sbjct: 591 ANDLDEGSNGDLRYSLMKRGNVNSEKFSVDPESGEIVVKASLDYEESGAYELRVQATD 648 Score = 63.7 bits (148), Expect = 7e-08 Identities = 42/133 (31%), Positives = 68/133 (51%), Gaps = 11/133 (8%) Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 P+S + + I + D+ND+ P+F + EN+ +G TI + A D D+G N + YS Sbjct: 1 PKSGNLQIRINVIDVNDNYPLFSKSLYKVQVVENANVGATILTLSATDLDDGVNGELVYS 60 Query: 726 I--KGG-DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVR 779 +G + + F+L G E+ ++DYE YE+ ++A +PP + Sbjct: 61 FAERGRFNPEDKFALNAHNG----EITLKGNIDYEE-NPAYEIRVQARDKGAPPRTAHSK 115 Query: 780 VEILVTDVNDNAP 792 V + V DVNDNAP Sbjct: 116 VLVEVIDVNDNAP 128 >UniRef50_UPI00006A2595 Cluster: Protocadherin-16 precursor (Dachsous-1) (Cadherin-19) (Fibroblast cadherin 1).; n=2; Xenopus tropicalis|Rep: Protocadherin-16 precursor (Dachsous-1) (Cadherin-19) (Fibroblast cadherin 1). - Xenopus tropicalis Length = 2375 Score = 322 bits (792), Expect = 7e-86 Identities = 238/740 (32%), Positives = 370/740 (50%), Gaps = 70/740 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I++LD ND++P F++ +Y A +E G+ ++ + A D D G N +V Y+ + A Sbjct: 1236 ISLLDLNDNAPRFQLPRYTAYTQEAQPDGSPLIQVLAEDPDQGLNGQVTYSFDQSQA--- 1292 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 ++D+FRID ++GA+ T A LDRE ++ ++V ATD+ SP L Sbjct: 1293 ---------------MKDLFRIDPQTGAITTAAILDREIWSQAHLVVIATDRGSP---PL 1334 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK--IKATDADVGANSAIR 188 +S+AT+ V + D NDN P T + ++SV ++ VI ++ T DV + A+ Sbjct: 1335 TSSATLTVLVTDVNDNSP-------TTPLQLELSVPEDAVIGSEILQVTGNDVDSGPALS 1387 Query: 189 YA-IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 Y ++ G + F++ G + L + LDYE +SY L ++ DG +L + + Sbjct: 1388 YTLLVDGAMEGAFTMLRYGGQIWLSRQLDYEDRKSYSLTVQTSDG---KHLTHAELTLTL 1444 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 +DVNDN+P F SL+Q S+ E+ G + V+A D D G N ++Y + V Sbjct: 1445 QDVNDNSPEFGKSLYQVSILEHAAAGTPLFTVRATDRDSGDNGRVSYRVLSP-----VGG 1499 Query: 308 PITIDPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 I P +G ++ + ++ + Q+ +LV A D G P ++ T F Sbjct: 1500 AFHIHPDNGTLFANKLVELDPQSPLVDVLVEARDHGSPSLASLTTVQFLVVDANDHSPTF 1559 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITS----QNG 419 QY + ED P G+ V+ L TDAD E+ L Y I GNT F + S NG Sbjct: 1560 SQSQYSASVPEDLPLGSTVLILEVTDADFTQENAALDYTILSGNTDNAFQVQSGMRFWNG 1619 Query: 420 R----GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAP 473 R G I + LDF+ Y LT+ A+D G RS + V IN+ D N+ PVF Sbjct: 1620 RFQQIGSIILTDSLDFEAISFYNLTLGASDRGVPQRSHSVPVLINVLDINDNPPVFPRPL 1679 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 Y+ + E+AP+G+ VL V A DSD G N + YS++S + F IN TGAI Sbjct: 1680 YSVLLSEEAPVGSEVLRVLAQDSDSGSNGLVHYSITS-------GDESRLFQINEATGAI 1732 Query: 534 TTNKLLDRETMSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592 + LDRE + + L V A DG G + V I V D+NDN+P F Q+ T +I E Sbjct: 1733 RLARHLDRERQALHALVVLALDGQGGQANFALVPVTIEVRDINDNKPYFPVQILTTSIRE 1792 Query: 593 DALVGTSVSQVGATDADVGLNGRIHYE-LDPKDREEG------SFVIDPASGVIRTNKAL 645 + T ++++ A D D G+ G++ Y LD G FV++ SG +R+ ++ Sbjct: 1793 NQPANTPLTKIHAIDLDTGVYGQLFYTMLDLAVAGSGMLMGKDMFVVNRTSGELRSKQSF 1852 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 D E + ++ A+D G S+TV V + + ++ PVF S F + E + G + Sbjct: 1853 DYERIKVFNMVVKAMDAGN--FSATVTVQVLVTGEDEYNPVFISPFFNFEVPEGAVKGES 1910 Query: 706 IGEIRAHDPDEGPNAVVHYS 725 +G ++A D DEG + VV YS Sbjct: 1911 LGHVQATDEDEGADGVVLYS 1930 Score = 296 bits (727), Expect = 5e-78 Identities = 245/764 (32%), Positives = 357/764 (46%), Gaps = 36/764 (4%) Query: 103 ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162 A LD E+ R+ ++++A Q S AT+ ++++D NDN P+F YT E Sbjct: 1207 AMLDYEQNPRHKLVLQAETQQH------LSFATLTISLLDLNDNAPRFQLPRYTAYTQE- 1259 Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ-FSIDSLSGDVSLVKTLDYEQVR 221 + D + ++ A D D G N + Y+ F ID +G ++ LD E Sbjct: 1260 -AQPDGSPLIQVLAEDPDQGLNGQVTYSFDQSQAMKDLFRIDPQTGAITTAAILDREIWS 1318 Query: 222 SYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA 281 LV+ A D GSP +++ L + + DVNDN+P L + SV E+ IG I++V Sbjct: 1319 QAHLVVIATDRGSPPLTSSATLTVLVTDVNDNSPTTPLQL-ELSVPEDAVIGSEILQVTG 1377 Query: 282 YDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341 D D G L+YT+ G ++ T+ G ++ S QLD E + Y L V +DG Sbjct: 1378 NDVDSG--PALSYTLL---VDGAMEGAFTMLRYGGQIWLSRQLDYEDRKSYSLTVQTSDG 1432 Query: 342 GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DN-RL 399 A F Y+V + E GTP+ T+ ATD D DN R+ Sbjct: 1433 ---KHLTHAELTLTLQDVNDNSPEFGKSLYQVSILEHAAAGTPLFTVRATDRDSGDNGRV 1489 Query: 400 HYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM--VQI 457 Y + G F I NG LD + VL V A D G S ++ VQ Sbjct: 1490 SYRVLSP-VGGAFHIHPDNGTLFANKLVELDPQSPLVDVL-VEARDHGSPSLASLTTVQF 1547 Query: 458 NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYS-LSSEISNE 515 + DAN+++P F + Y+ASV ED P+G+TVL++ TD+D NA + Y+ LS N Sbjct: 1548 LVVDANDHSPTFSQSQYSASVPEDLPLGSTVLILEVTDADFTQENAALDYTILSGNTDNA 1607 Query: 516 AVAHHDQQFVIN--PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 +F Q G+I LD E +S Y LT+ A D GVP S + V I+V+D Sbjct: 1608 FQVQSGMRFWNGRFQQIGSIILTDSLDFEAISFYNLTLGASDRGVPQRSHSVPVLINVLD 1667 Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633 +NDN PVF + LY+ + E+A VG+ V +V A D+D G NG +HY + D E F I+ Sbjct: 1668 INDNPPVFPRPLYSVLLSEEAPVGSEVLRVLAQDSDSGSNGLVHYSITSGD-ESRLFQIN 1726 Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDG-GTPPQSSTVIVHIKIEDINDSPPVFESDCL 692 A+G IR + LDRE A H L +A+DG G + V V I++ DIND+ P F L Sbjct: 1727 EATGAIRLARHLDRERQALHALVVLALDGQGGQANFALVPVTIEVRDINDNKPYFPVQIL 1786 Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ----GSDKAEL 748 T I EN P T + +I A D D G + Y++ + S L + EL Sbjct: 1787 TTSIRENQPANTPLTKIHAIDLDTGVYGQLFYTMLDLAVAGSGMLMGKDMFVVNRTSGEL 1846 Query: 749 VTMVDLDYESPRKKYELVIRAASPPLWN-DVRVEILVTDVNDNAPVMKDFQIIFNNYKDC 807 + DYE K + +V++A ++ V V++LVT ++ PV F + Sbjct: 1847 RSKQSFDYER-IKVFNMVVKAMDAGNFSATVTVQVLVTGEDEYNPVFISPFFNFEVPEGA 1905 Query: 808 FPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTL 851 G V A D D + +NETTG++ L Sbjct: 1906 VKGESLGHVQATDEDEGADGVVLYSFSKPSPYFGINETTGNIYL 1949 Score = 286 bits (701), Expect = 7e-75 Identities = 217/749 (28%), Positives = 360/749 (48%), Gaps = 51/749 (6%) Query: 177 TDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGS 234 T +G+ + GN ++ S+ +G +++ + LDYEQ ++LV++A+ + Sbjct: 1169 THVHMGSMGTVWAQYGNGNARVCGSLVPPAGQITVAQAAMLDYEQNPRHKLVLQAE---T 1225 Query: 235 PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294 + L I++ D+NDNAPRF + E P G +++V A D D+G+N ++TY Sbjct: 1226 QQHLSFATLTISLLDLNDNAPRFQLPRYTAYTQEAQPDGSPLIQVLAEDPDQGLNGQVTY 1285 Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354 + ++ IDP++G + T+ LDRE ++ L+V ATD G PP +++AT Sbjct: 1286 SFDQSQAMKDL---FRIDPQTGAITTAAILDREIWSQAHLVVIATDRGSPPLTSSATLTV 1342 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEI-TGGNTRGRFS 413 P Q E+ + ED G+ ++ +T D D L Y + G G F+ Sbjct: 1343 LVTDVNDNSPT-TPLQLELSVPEDAVIGSEILQVTGNDVDSGPALSYTLLVDGAMEGAFT 1401 Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAP 473 + G+ I +++ LD++ + Y LTV +D G A + + + D N+ +P F + Sbjct: 1402 MLRYGGQ--IWLSRQLDYEDRKSYSLTVQTSD-GKHLTHAELTLTLQDVNDNSPEFGKSL 1458 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 Y S+ E A GT + V ATD D G N +++Y + S + F I+P G + Sbjct: 1459 YQVSILEHAAAGTPLFTVRATDRDSGDNGRVSYRVLSPVGGA--------FHIHPDNGTL 1510 Query: 534 TTNKLLDRETMSGYL-LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592 NKL++ + S + + V ARD G PSL+ T V+ VVD ND+ P F Q Y+A++ E Sbjct: 1511 FANKLVELDPQSPLVDVLVEARDHGSPSLASLTTVQFLVVDANDHSPTFSQSQYSASVPE 1570 Query: 593 DALVGTSVSQVGATDADVGL-NGRIHYELDPKDREEGSFVIDPAS----------GVIRT 641 D +G++V + TDAD N + Y + + +F + G I Sbjct: 1571 DLPLGSTVLILEVTDADFTQENAALDYTI-LSGNTDNAFQVQSGMRFWNGRFQQIGSIIL 1629 Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701 +LD E+++ ++L A D G P +S +V V I + DIND+PPVF + +SE +P Sbjct: 1630 TDSLDFEAISFYNLTLGASDRGVPQRSHSVPVLINVLDINDNPPVFPRPLYSVLLSEEAP 1689 Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761 +G+ + + A D D G N +VHYSI GD+S F + G+ L +D + ++ Sbjct: 1690 VGSEVLRVLAQDSDSGSNGLVHYSITSGDESRLFQINEATGA--IRLARHLDRERQALHA 1747 Query: 762 KYELVIRA-ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAY 819 L + + V V I V D+NDN P QI+ + ++ P P ++ A Sbjct: 1748 LVVLALDGQGGQANFALVPVTIEVRDINDNKPYF-PVQILTTSIRENQPANTPLTKIHAI 1806 Query: 820 DAD--VTDKLQYRIL------SG--NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSV 869 D D V +L Y +L SG ++ ++N T+G + + K+ M V Sbjct: 1807 DLDTGVYGQLFYTMLDLAVAGSGMLMGKDMFVVNRTSGELRSKQSFDYERIKVFNMVVKA 1866 Query: 870 TDGVNEIKAMMQLSVRLITEEMLLNSITV 898 D N A + + V L+T E N + + Sbjct: 1867 MDAGN-FSATVTVQV-LVTGEDEYNPVFI 1893 Score = 255 bits (624), Expect = 1e-65 Identities = 206/694 (29%), Positives = 326/694 (46%), Gaps = 54/694 (7%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F I+ SG L R +LDRE Y + V A+ A P + ++T T+ V + D+NDN P+ Sbjct: 209 FSIEADSGWLYVRGALDRESREAYVLAVLAS--AGPGTR--TATCTVRVRVTDENDNSPR 264 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209 SE+ + +S E+ + + ++ ATD D G N + Y + + F I+ +G++ Sbjct: 265 LSEERFFLSATENRPPGET--VGRVSATDRDAGPNGRVSYRL--PPLESDFHINPHTGEL 320 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF-YTSLFQE---S 265 S + LD E +Y+L++ AQDGG+P RS T + I + D NDNAP F + + +E Sbjct: 321 STRRVLDRELQATYQLLVIAQDGGAPPRSVTGTVHITVLDENDNAPTFLHPNAGKEISLQ 380 Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN--VDLPITIDPRSGWVYTSGQ 323 V E G I +QA D DEG N +TY++ Y + V P+ + +++ Sbjct: 381 VMEGKKSGMFIASLQAKDPDEGENGTVTYSLAGTGYKTDRLVVAPLAVALAPPPIHSMPM 440 Query: 324 LDRETQAKYQLLVTATDGGDPPR--SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381 D T PP + T P + E P Sbjct: 441 HD---------FSPPTPPSWPPHVFNVTPFTAFQVIPASRYPSKSNPSSLVLSPMEGLAP 491 Query: 382 GTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441 G+ + +L A +R++ + G F + Q G I + LDF+ + R+ V Sbjct: 492 GSLLGSL-APRMPHGSRIYTLLD--EPHGIFMVDGQTGS--IFLVGELDFESQPRFSFRV 546 Query: 442 SATDSGGRS------DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495 S + S +++ + D N+++P F P T V EDA +G++V A+D Sbjct: 547 SVEEVREASLGYVPPHVVHIEVEVQDRNDHSPAFPEDPLTLVVPEDAHVGSSVFTFQASD 606 Query: 496 SD-VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554 D G N+Q+ YSL + F ++ +TG + + LDRE +S YLL V A Sbjct: 607 HDGPGPNSQVRYSLLRQDPGSP----GSTFRLDAETGVLYVAQALDREEVSSYLLVVEAS 662 Query: 555 DGGV---PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG 611 D V S + + + D ND+ P F L + ED VG++ + A D D+G Sbjct: 663 DQAVNVSQQRSTSVTARVFISDRNDHAPQFITPLVVW-LPEDLPVGSTAIYMVAQDPDLG 721 Query: 612 LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671 NG++ Y+L +EG F + P+SG + + LDRE+ ++L VA+D G+P SST Sbjct: 722 DNGKVGYQL-VGGNDEGKFQLHPSSGALTVVRTLDRETTEGYNLTVVAMDHGSPRLSSTQ 780 Query: 672 IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD 731 + + + D+ND P FE + EN P+GTT+ + A D D G + V Y GG Sbjct: 781 TLSVSLLDVNDEAPSFEKPQYDAQVQENQPVGTTVLRVVALDRDLGQSGRVTY---GGVS 837 Query: 732 SNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765 + F+L+ G L T V LD E+ ++ Y+L Sbjct: 838 GDEFALDPETG----VLTTKVPLDREA-KELYKL 866 Score = 190 bits (462), Expect = 6e-46 Identities = 209/772 (27%), Positives = 334/772 (43%), Gaps = 71/772 (9%) Query: 194 GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDN 253 G+ + S+D SG +SLV+ LD EQ L ++ + G P+ + +L + I DVNDN Sbjct: 3 GDPRGLLSLDPHSGLLSLVRPLDREQTEKLLLEVQGRSGAPPAYARA-RLTLYITDVNDN 61 Query: 254 APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313 P F + + +PIG I R QA D D G N ++ Y + D G P +ID Sbjct: 62 PPAFPSPFHTLRLQSPIPIGSVIFRAQATDPDTGFNGQVYYEL---DSPG----PFSIDG 114 Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373 SG + +G L +E +Y + V A+DGG P S+ A Y V Sbjct: 115 -SGQLRATGLLSQE---RYDVRVLASDGGTPQLSS-ALELTVLLMELQKEPACGASDYRV 169 Query: 374 ELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432 E+ E PP + ++ + A + +L Y + FSI + +G + V LD + Sbjct: 170 EVREGSPPLSRLLQVRAQPPGAGEGQLIYRLRPDADAVGFSIEADSG--WLYVRGALDRE 227 Query: 433 QERRYVLTVSATDSGG-RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491 YVL V A+ G R+ T V++ +TD N+ +P + S E+ P G TV V Sbjct: 228 SREAYVLAVLASAGPGTRTATCTVRVRVTDENDNSPRLSEERFFLSATENRPPGETVGRV 287 Query: 492 SATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTV 551 SATD D G N +++Y L S+ F INP TG ++T ++LDRE + Y L V Sbjct: 288 SATDRDAGPNGRVSYRLPPLESD---------FHINPHTGELSTRRVLDRELQATYQLLV 338 Query: 552 TARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ----QLYTANIMEDALVGTSVSQVGATD 607 A+DGG P S T V I+V+D NDN P F + + +ME G ++ + A D Sbjct: 339 IAQDGGAPPRSVTGTVHITVLDENDNAPTFLHPNAGKEISLQVMEGKKSGMFIASLQAKD 398 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 D G NG + Y L + V+ P + + S+ HD + PP Sbjct: 399 PDEGENGTVTYSLAGTGYKTDRLVVAPLAVALAPPPI---HSMPMHDF-SPPTPPSWPPH 454 Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 V + I S +S+ + +S G G + P+ Y++ Sbjct: 455 VFNVTPFTAFQVIPASRYPSKSNPSSLVLSPME--GLAPGSLLGSLAPRMPHGSRIYTLL 512 Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYES-PRKKYEL---VIRAAS----PPLWNDVR 779 + F ++ + GS + + +LD+ES PR + + +R AS PP + V Sbjct: 513 -DEPHGIFMVDGQTGS----IFLVGELDFESQPRFSFRVSVEEVREASLGYVPP--HVVH 565 Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD---VTDKLQYRIL---S 833 +E+ V D ND++P + + +D A D D +++Y +L Sbjct: 566 IEVEVQDRNDHSPAFPEDPLTLVVPEDAHVGSSVFTFQASDHDGPGPNSQVRYSLLRQDP 625 Query: 834 GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLL 893 G+ + L+ TG + ++ L+ + V +D + SV T + + Sbjct: 626 GSPGSTFRLDAETGVLYVAQALDREEVSSYLLVVEASDQAVNVSQQRSTSV---TARVFI 682 Query: 894 NSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGN 945 + ND A QF++PL+ + + L P + I+ V D D+ N Sbjct: 683 SD----RND-HAPQFITPLVVWLPEDL------PVGSTAIYMVAQDPDLGDN 723 Score = 186 bits (453), Expect = 8e-45 Identities = 214/824 (25%), Positives = 351/824 (42%), Gaps = 75/824 (9%) Query: 92 IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151 +D SG L LDRE+ + + V+ A P R A + + I D NDN P F Sbjct: 11 LDPHSGLLSLVRPLDREQTEKLLLEVQGRSGAPPAYAR----ARLTLYITDVNDNPPAFP 66 Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSL 211 +T+ + I + VI + +ATD D G N + Y + ++ FSID SG + Sbjct: 67 SPFHTLRLQSPIPI--GSVIFRAQATDPDTGFNGQVYYEL---DSPGPFSIDG-SGQLRA 120 Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271 L E+ Y + + A DGG+P S+ +L + + ++ P S ++ V E P Sbjct: 121 TGLLSQER---YDVRVLASDGGTPQLSSALELTVLLMEL-QKEPACGASDYRVEVREGSP 176 Query: 272 IGYSIVRVQAYDADEGVNAELTYTM-TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA 330 +++V+A G +L Y + D D G +I+ SGW+Y G LDRE++ Sbjct: 177 PLSRLLQVRAQPPGAG-EGQLIYRLRPDADAVG-----FSIEADSGWLYVRGALDRESRE 230 Query: 331 KYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTA 390 Y L V A+ G R+AT T ++ + E+ PPG V ++A Sbjct: 231 AYVLAVLAS-AGPGTRTATCTVRVRVTDENDNSPRLSEERFFLSATENRPPGETVGRVSA 289 Query: 391 TDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG 448 TD D + R+ Y + F I G ++ + LD + + Y L V A D G Sbjct: 290 TDRDAGPNGRVSYRLP--PLESDFHINPHTGE--LSTRRVLDRELQATYQLLVIAQDGGA 345 Query: 449 --RSDTAMVQINITDANNYAPVF--ENA--PYTASVFEDAPIGTTVLVVSATDSDVGINA 502 RS T V I + D N+ AP F NA + V E G + + A D D G N Sbjct: 346 PPRSVTGTVHITVLDENDNAPTFLHPNAGKEISLQVMEGKKSGMFIASLQAKDPDEGENG 405 Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 +TYSL+ + + V+ P A+ + +M + + P + Sbjct: 406 TVTYSLA------GTGYKTDRLVVAPLAVALAPPPI---HSMPMHDFSPPTPPSWPPHVF 456 Query: 563 DTTD-VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621 + T V+ + + ME G S +G+ + RI+ L Sbjct: 457 NVTPFTAFQVIPASRYPSKSNPSSLVLSPMEGLAPG---SLLGSLAPRMPHGSRIYTLL- 512 Query: 622 PKDREEGSFVIDPASGVIRTNKALDRES-------VATHDLKAVAIDGGTPPQSSTVIVH 674 D G F++D +G I LD ES V+ +++ ++ G PP V + Sbjct: 513 --DEPHGIFMVDGQTGSIFLVGELDFESQPRFSFRVSVEEVREASL-GYVPPH--VVHIE 567 Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSN 733 ++++D ND P F D LT + E++ +G+++ +A D D GPN+ V YS+ D + Sbjct: 568 VEVQDRNDHSPAFPEDPLTLVVPEDAHVGSSVFTFQASDHDGPGPNSQVRYSLLRQDPGS 627 Query: 734 SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA------SPPLWNDVRVEILVTDV 787 S R ++ L LD E Y LV+ A+ S V + ++D Sbjct: 628 PGS-TFRLDAETGVLYVAQALDREEV-SSYLLVVEASDQAVNVSQQRSTSVTARVFISDR 685 Query: 788 NDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVTD--KLQYRILSGNNANLILLNE 844 ND+AP +++ + PVG + A D D+ D K+ Y+++ GN+ L+ Sbjct: 686 NDHAPQFITPLVVW--LPEDLPVGSTAIYMVAQDPDLGDNGKVGYQLVGGNDEGKFQLHP 743 Query: 845 TTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLI 887 ++G++T+ L+ + + V D G + + LSV L+ Sbjct: 744 SSGALTVVRTLDRETTEGYNLTVVAMDHGSPRLSSTQTLSVSLL 787 Score = 185 bits (450), Expect = 2e-44 Identities = 116/332 (34%), Positives = 173/332 (52%), Gaps = 27/332 (8%) Query: 4 PFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTI 62 P +H ++ V D NDHSP F V E A G++V T +A+D D G N++V Y+ Sbjct: 561 PHVVHIEVEVQDRNDHSPAFPEDPLTLVVPEDAHVGSSVFTFQASDHDGPGPNSQVRYS- 619 Query: 63 ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122 L+ D +P FR+D +G L +LDRE+V+ Y ++V+A+DQ Sbjct: 620 -LLRQDPGSP--------------GSTFRLDAETGVLYVAQALDREEVSSYLLVVEASDQ 664 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 A VS + S++ T V I D ND+ PQF V + ED+ V + + A D D+G Sbjct: 665 AVNVSQQRSTSVTARVFISDRNDHAPQFI-TPLVVWLPEDLPVGSTAIY--MVAQDPDLG 721 Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 N + Y ++GGN + +F + SG +++V+TLD E Y L + A D GSP S+T Sbjct: 722 DNGKVGYQLVGGNDEGKFQLHPSSGALTVVRTLDRETTEGYNLTVVAMDHGSPRLSSTQT 781 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 L +++ DVND AP F + V EN P+G +++RV A D D G + +TY D Sbjct: 782 LSVSLLDVNDEAPSFEKPQYDAQVQENQPVGTTVLRVVALDRDLGQSGRVTYGGVSGD-- 839 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQL 334 +DP +G + T LDRE + Y+L Sbjct: 840 -----EFALDPETGVLTTKVPLDREAKELYKL 866 Score = 171 bits (417), Expect = 2e-40 Identities = 118/392 (30%), Positives = 185/392 (47%), Gaps = 22/392 (5%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDI-GKNAEVEYTIELVTAD 68 Q V+D NDHSP F QY ASV E G+TVL L+ TD D +NA ++YTI ++ + Sbjct: 1546 QFLVVDANDHSPTFSQSQYSASVPEDLPLGSTVLILEVTDADFTQENAALDYTI--LSGN 1603 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 T N Q + G+++ SLD E ++ Y + + A+D+ P Sbjct: 1604 TDNAFQVQSGMRFWNGRFQQI-------GSIILTDSLDFEAISFYNLTLGASDRGVP--- 1653 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 + S + + +N++D NDN P F Y+V + E+ V + ++ A D+D G+N + Sbjct: 1654 QRSHSVPVLINVLDINDNPPVFPRPLYSVLLSEEAPVGSE--VLRVLAQDSDSGSNGLVH 1711 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG-GSPSRSNTTQLLINI 247 Y+I G+ F I+ +G + L + LD E+ + LV+ A DG G + + I + Sbjct: 1712 YSITSGDESRLFQINEATGAIRLARHLDRERQALHALVVLALDGQGGQANFALVPVTIEV 1771 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 RD+NDN P F + S+ EN P + ++ A D D GV +L YTM D G+ L Sbjct: 1772 RDINDNKPYFPVQILTTSIRENQPANTPLTKIHAIDLDTGVYGQLFYTMLDLAVAGSGML 1831 Query: 308 ----PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 ++ SG + + D E + ++V A D G+ SAT T Sbjct: 1832 MGKDMFVVNRTSGELRSKQSFDYERIKVFNMVVKAMDAGN--FSATVTVQVLVTGEDEYN 1889 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395 F+ + E+ E G + + ATD DE Sbjct: 1890 PVFISPFFNFEVPEGAVKGESLGHVQATDEDE 1921 Score = 154 bits (373), Expect = 4e-35 Identities = 109/363 (30%), Positives = 176/363 (48%), Gaps = 26/363 (7%) Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS----NTTQLLINIRDVNDNAP 255 F +D +G + LV LD+E + + ++ S + + + ++D ND++P Sbjct: 519 FMVDGQTGSIFLVGELDFESQPRFSFRVSVEEVREASLGYVPPHVVHIEVEVQDRNDHSP 578 Query: 256 RFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYTGNVDLPITIDPR 314 F V E+ +G S+ QA D D G N+++ Y++ +D G+ +D Sbjct: 579 AFPEDPLTLVVPEDAHVGSSVFTFQASDHDGPGPNSQVRYSLLRQD-PGSPGSTFRLDAE 637 Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGG---DPPRSATATXXXXXXXXXXXXXXFMPGQY 371 +G +Y + LDRE + Y L+V A+D RS + T F+ Sbjct: 638 TGVLYVAQALDREEVSSYLLVVEASDQAVNVSQQRSTSVTARVFISDRNDHAPQFIT-PL 696 Query: 372 EVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 V L ED P G+ + + A D D ++ ++ Y++ GGN G+F + +G +TV + L Sbjct: 697 VVWLPEDLPVGSTAIYMVAQDPDLGDNGKVGYQLVGGNDEGKFQLHPSSGA--LTVVRTL 754 Query: 430 DFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 D + Y LTV A D G S T + +++ D N+ AP FE Y A V E+ P+GTT Sbjct: 755 DRETTEGYNLTVVAMDHGSPRLSSTQTLSVSLLDVNDEAPSFEKPQYDAQVQENQPVGTT 814 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 VL V A D D+G + ++TY +S + +F ++P+TG +TT LDRE Y Sbjct: 815 VLRVVALDRDLGQSGRVTYG---GVSGD-------EFALDPETGVLTTKVPLDREAKELY 864 Query: 548 LLT 550 LT Sbjct: 865 KLT 867 Score = 147 bits (357), Expect = 3e-33 Identities = 109/362 (30%), Positives = 176/362 (48%), Gaps = 22/362 (6%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATD-QASPVSDRLSSTATIHVNIIDDNDNY 147 +F +DG++G++ LD E R++ V + + + + I V + D ND+ Sbjct: 518 IFMVDGQTGSIFLVGELDFESQPRFSFRVSVEEVREASLGYVPPHVVHIEVEVQDRNDHS 577 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSAIRYAIIG---GNTQMQFSID 203 P F E T+ V ED V + + +A+D D G NS +RY+++ G+ F +D Sbjct: 578 PAFPEDPLTLVVPEDAHVGSS--VFTFQASDHDGPGPNSQVRYSLLRQDPGSPGSTFRLD 635 Query: 204 SLSGDVSLVKTLDYEQVRSYRLVIRAQDGG---SPSRSNTTQLLINIRDVNDNAPRFYTS 260 + +G + + + LD E+V SY LV+ A D S RS + + I D ND+AP+F T Sbjct: 636 AETGVLYVAQALDREEVSSYLLVVEASDQAVNVSQQRSTSVTARVFISDRNDHAPQFITP 695 Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT 320 L + E++P+G + + + A D D G N ++ Y + GN + + P SG + Sbjct: 696 LVVW-LPEDLPVGSTAIYMVAQDPDLGDNGKVGYQLVG----GNDEGKFQLHPSSGALTV 750 Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380 LDRET Y L V A D G P S+T T F QY+ ++ E++P Sbjct: 751 VRTLDRETTEGYNLTVVAMDHGSPRLSSTQTLSVSLLDVNDEAPSFEKPQYDAQVQENQP 810 Query: 381 PGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYV 438 GT V+ + A D D + R+ Y GG + F++ + G++T PLD + + Y Sbjct: 811 VGTTVLRVVALDRDLGQSGRVTY---GGVSGDEFALDPET--GVLTTKVPLDREAKELYK 865 Query: 439 LT 440 LT Sbjct: 866 LT 867 Score = 136 bits (330), Expect = 6e-30 Identities = 117/393 (29%), Positives = 180/393 (45%), Gaps = 31/393 (7%) Query: 404 TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT-AMVQINITDA 462 + G+ RG S+ +G L+++ +PLD +Q + +L V + A + + ITD Sbjct: 1 SSGDPRGLLSLDPHSG--LLSLVRPLDREQTEKLLLEVQGRSGAPPAYARARLTLYITDV 58 Query: 463 NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522 N+ P F + +T + PIG+ + ATD D G N Q+ Y L S Sbjct: 59 NDNPPAFPSPFHTLRLQSPIPIGSVIFRAQATDPDTGFNGQVYYELDSP----------G 108 Query: 523 QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582 F I+ +G + LL +E Y + V A DGG P LS ++ + ++++ EP Sbjct: 109 PFSIDG-SGQLRATGLLSQER---YDVRVLASDGGTPQLSSALELTVLLMELQ-KEPACG 163 Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642 Y + E + + + QV A G G++ Y L P D + F I+ SG + Sbjct: 164 ASDYRVEVREGSPPLSRLLQVRAQPPGAG-EGQLIYRLRP-DADAVGFSIEADSGWLYVR 221 Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 ALDRES + L AV G +++T V +++ D ND+ P + +EN P Sbjct: 222 GALDRESREAYVL-AVLASAGPGTRTATCTVRVRVTDENDNSPRLSEERFFLSATENRPP 280 Query: 703 GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762 G T+G + A D D GPN V Y + + + F + G EL T LD E + Sbjct: 281 GETVGRVSATDRDAGPNGRVSYRLPPLE--SDFHINPHTG----ELSTRRVLDREL-QAT 333 Query: 763 YELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792 Y+L++ A +PP V I V D NDNAP Sbjct: 334 YQLLVIAQDGGAPPRSVTGTVHITVLDENDNAP 366 Score = 119 bits (287), Expect = 1e-24 Identities = 110/355 (30%), Positives = 171/355 (48%), Gaps = 26/355 (7%) Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS----DTTDVEISVVDVNDNEP 579 F+++ QTG+I LD E+ + V+ + SL +E+ V D ND+ P Sbjct: 519 FMVDGQTGSIFLVGELDFESQPRFSFRVSVEEVREASLGYVPPHVVHIEVEVQDRNDHSP 578 Query: 580 VFKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDR-EEGS-FVIDPAS 636 F + T + EDA VG+SV A+D D G N ++ Y L +D GS F +D + Sbjct: 579 AFPEDPLTLVVPEDAHVGSSVFTFQASDHDGPGPNSQVRYSLLRQDPGSPGSTFRLDAET 638 Query: 637 GVIRTNKALDRESVATHDLKAVAIDGG---TPPQSSTVIVHIKIEDINDSPPVFESDCLT 693 GV+ +ALDRE V+++ L A D + +S++V + I D ND P F + L Sbjct: 639 GVLYVAQALDREEVSSYLLVVEASDQAVNVSQQRSTSVTARVFISDRNDHAPQFITP-LV 697 Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753 ++ E+ P+G+T + A DPD G N V Y + GG+D F L G+ L + Sbjct: 698 VWLPEDLPVGSTAIYMVAQDPDLGDNGKVGYQLVGGNDEGKFQLHPSSGA----LTVVRT 753 Query: 754 LDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV 810 LD E+ + Y L + A SP L + + + + DVND AP + Q ++ PV Sbjct: 754 LDRETT-EGYNLTVVAMDHGSPRLSSTQTLSVSLLDVNDEAPSFEKPQ-YDAQVQENQPV 811 Query: 811 G-PFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKL 862 G RV A D D+ + ++ Y +SG+ L+ TG +T L+ +L Sbjct: 812 GTTVLRVVALDRDLGQSGRVTYGGVSGDE---FALDPETGVLTTKVPLDREAKEL 863 Score = 79.0 bits (186), Expect = 2e-12 Identities = 57/186 (30%), Positives = 84/186 (45%), Gaps = 26/186 (13%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ V D ND+SP +++ S E G TV + ATD+D G N V Y + + +D Sbjct: 252 RVRVTDENDNSPRLSEERFFLSATENRPPGETVGRVSATDRDAGPNGRVSYRLPPLESD- 310 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 F I+ +G L TR LDRE A Y +LV A D +P Sbjct: 311 --------------------FHINPHTGELSTRRVLDRELQATYQLLVIAQDGGAPPR-- 348 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKT--YTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 S T T+H+ ++D+NDN P F +S+ IA ++A D D G N + Sbjct: 349 -SVTGTVHITVLDENDNAPTFLHPNAGKEISLQVMEGKKSGMFIASLQAKDPDEGENGTV 407 Query: 188 RYAIIG 193 Y++ G Sbjct: 408 TYSLAG 413 Score = 41.9 bits (94), Expect = 0.25 Identities = 27/87 (31%), Positives = 34/87 (39%), Gaps = 1/87 (1%) Query: 334 LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTAT-D 392 + V ATD G+PP S+TA F E+ L E+ P G+ V T TA Sbjct: 916 VFVQATDLGEPPLSSTAVLVVHLREEAPQGPRFPQEAIEISLPENSPEGSVVGTATAAHT 975 Query: 393 ADEDNRLHYEITGGNTRGRFSITSQNG 419 R+ Y GN G I G Sbjct: 976 GGSTGRISYSFLSGNENGALRIHPTTG 1002 Score = 41.9 bits (94), Expect = 0.25 Identities = 22/85 (25%), Positives = 39/85 (45%), Gaps = 1/85 (1%) Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 A D G PP SST ++ + + + P F + + + ENSP G+ +G A G Sbjct: 920 ATDLGEPPLSSTAVLVVHLREEAPQGPRFPQEAIEISLPENSPEGSVVGTATAAHTG-GS 978 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGS 743 + YS G+++ + + G+ Sbjct: 979 TGRISYSFLSGNENGALRIHPTTGT 1003 Score = 38.7 bits (86), Expect = 2.3 Identities = 24/65 (36%), Positives = 35/65 (53%), Gaps = 6/65 (9%) Query: 2 SVPFCIHQQINVLDCNDHSPVF----EMQQYEASVREGASSGTTVLTLKATDQDIGKNAE 57 SV +H I VLD ND++P F ++ V EG SG + +L+A D D G+N Sbjct: 349 SVTGTVH--ITVLDENDNAPTFLHPNAGKEISLQVMEGKKSGMFIASLQAKDPDEGENGT 406 Query: 58 VEYTI 62 V Y++ Sbjct: 407 VTYSL 411 Score = 38.7 bits (86), Expect = 2.3 Identities = 27/98 (27%), Positives = 46/98 (46%), Gaps = 5/98 (5%) Query: 227 IRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE 286 ++A D G P S+T L++++R+ PRF + S+ EN P G S+V Sbjct: 918 VQATDLGEPPLSSTAVLVVHLREEAPQGPRFPQEAIEISLPENSPEG-SVVGTATAAHTG 976 Query: 287 GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 G ++Y+ +GN + + I P +G +G L Sbjct: 977 GSTGRISYSF----LSGNENGALRIHPTTGTWGNTGTL 1010 >UniRef50_UPI0000660D80 Cluster: Homolog of Brachydanio rerio "Protocadherin1-alpha-av15-vCP.; n=1; Takifugu rubripes|Rep: Homolog of Brachydanio rerio "Protocadherin1-alpha-av15-vCP. - Takifugu rubripes Length = 1420 Score = 321 bits (789), Expect = 2e-85 Identities = 261/894 (29%), Positives = 415/894 (46%), Gaps = 79/894 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D NDHSP F + + E S GT A D D G N+ Y L Sbjct: 3 VEITDVNDHSPSFPETEQRFEMAEHTSPGTRFELHAARDPDTGLNSIRTYI--------L 54 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + D + F L+ + SLDREK +++++V A D P + Sbjct: 55 SANDHFGIEMSQSDEEKTPF--------LVLKQSLDREKSNKHSLVVTAVDGGKP---QR 103 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S T + + ++D+NDN P+F + TY + + E++ V + K+ A D D GAN I Y+ Sbjct: 104 SGTLNVSIIVLDNNDNIPRFDKDTYQIEISENVPV--GRTVTKVSAIDQDEGANGEIEYS 161 Query: 191 I---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 + + N F ++ L+G++ L LD+E+ +Y+L I A D G+P + ++++ + Sbjct: 162 LSKTLVRNVYDIFELNPLNGEIRLKGMLDFEESETYKLDIEASDKGTPPFRSRCRVIVKV 221 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 DV + R S +V E+ G I + D D GVN ++ +T D+ Sbjct: 222 IDVKSSRNR---SDITNTVPEDSKPGTVISLISVSDKDSGVNGKIISRITS-------DV 271 Query: 308 PITIDP----RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 P + P + + T LDRE + Y++++ A D G+PP S + Sbjct: 272 PFELKPSYKENTYSIVTKAFLDREMTSHYEIIIQAVDCGEPPLSTVRSIQVQVSDINDNS 331 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRF-SITSQNGR 420 F+ + L E+ G + +++ATD D E+ + Y I N F ++ S+NG+ Sbjct: 332 PRFIQNPLQFYLVENNVAGASIFSVSATDNDVSENAVISYSIARLNDVTSFLNVNSENGQ 391 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYAPVF---ENAPYT 475 I+ + DF+ + + V A+DSG S ++ V +N I D N+ APV ++ + Sbjct: 392 --ISALKSFDFETLKTFQFQVVASDSGSPSLSSNVTVNVFILDQNDNAPVILYPVSSNGS 449 Query: 476 ASVFEDAP----IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 A E+ P G V V A D+D+G N + +SL ++S+ ++ D++ Sbjct: 450 AEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSL-QQVSDHSLFGEDRKVPF----- 503 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 + K LDRET S + L +TA DGG P+ S D+ I V+DVNDN PVF ++LY++ I Sbjct: 504 -LVLQKQLDRETASSHKLQLTALDGGKPAKSGAIDIIIDVLDVNDNSPVFAKELYSSTIK 562 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHY----ELDPKDREEGSFVIDPASGVIRTNKALDR 647 E+ +GT V Q+ ATD D G NG I Y E+D K F ID +G IR +D Sbjct: 563 ENVPIGTVVIQINATDLDEGANGEIIYMFGKEMDSK--LMNVFDIDTNTGEIRVIGKIDF 620 Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 E + +L A D P ++ V I + DIND+ P E + I E+S +GTT+ Sbjct: 621 EESRSFELDIQASDKAQAPLTTDKSVMISVIDINDNAPEIEVTSFSSSIKEDSKLGTTVA 680 Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 I D D G N V S+K + + F+L ++ +VT LD E KY+L I Sbjct: 681 LISVSDLDSGINGKVICSLK---EDSPFNLSPSLQNNMYAVVTRSQLDREIV-SKYDLTI 736 Query: 768 RA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVT 824 A P + + ++V+DVNDN+P F ++ P V A D D Sbjct: 737 VAKDTGEPTFLTEKTISLIVSDVNDNSPKFLSSSYGFYVTENNSPGASVFSVKASDCDEN 796 Query: 825 DK--LQY-----RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + + Y R L N A+ + +N TG + + K +V +D Sbjct: 797 NNAMITYHIRRERTLDANFASFLNINSETGDIFALKSFDFETLKTFQFQVVASD 850 Score = 316 bits (777), Expect = 4e-84 Identities = 235/810 (29%), Positives = 389/810 (48%), Gaps = 63/810 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+V+D ND++P E+ + +S++E + GTTV + +D D G N +V +++ + L Sbjct: 648 ISVIDINDNAPEIEVTSFSSSIKEDSKLGTTVALISVSDLDSGINGKVICSLKEDSPFNL 707 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +P + A++TR+ LDRE V++Y + + A D P Sbjct: 708 SPS------------------LQNNMYAVVTRSQLDREIVSKYDLTIVAKDTGEPT---F 746 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + TI + + D NDN P+F +Y V E+ S + +KA+D D N+ I Y Sbjct: 747 LTEKTISLIVSDVNDNSPKFLSSSYGFYVTENNS--PGASVFSVKASDCDENNNAMITYH 804 Query: 191 I-----IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 I + N +I+S +GD+ +K+ D+E +++++ + A D GSPS S+ + + Sbjct: 805 IRRERTLDANFASFLNINSETGDIFALKSFDFETLKTFQFQVVASDSGSPSLSSNVTVNV 864 Query: 246 NIRDVNDNAPRFYTSLFQ-------ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 I D NDNAP + E + NV G+ + +V+AYDAD G N L +++ Sbjct: 865 FILDQNDNAPVILYPVSSNGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQQ 924 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358 + L +D +G + T +A+++L++ D G+ SATAT Sbjct: 925 ---VSDHSL-FGLDRYTGQIRTLRSFTETDEAEHKLVILVKDNGNVSLSATATVMVKLVE 980 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITS 416 Q + ED G A DAD + HY+++ N R + Sbjct: 981 PKEAFAA-SDLQSSAKDDEDMLAGARFQLKGAQDADSGRFSVQHYKLSQ-NDHFRLEVKD 1038 Query: 417 QNGRG---LITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFEN 471 + G ++ V + LD + + L ++A D G +S + IN+ D N+ APVF Sbjct: 1039 RGKDGKIPILVVQKSLDRETAGSHSLVLTALDGGKPPKSGEMNILINVLDINDNAPVFSK 1098 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 Y+ + E+ IGTTV+ V+ATD+D G N ++ YS S+ ++ + F IN TG Sbjct: 1099 DVYSVMLHENTLIGTTVIQVNATDADDGPNGEVVYSFSNSMNQNVL----DLFDINEITG 1154 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 IT +D E Y + V A D G L V I + DVNDN P + +++ I Sbjct: 1155 EITVKGPIDYEENERYEIEVEASDKGFVPLKTEKTVIIDITDVNDNAPEIEVTSFSSFIP 1214 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG----VIRTNKALDR 647 ED+ GT+V+ + D D G+NG++ + + F + P+ + T ALDR Sbjct: 1215 EDSRPGTTVAHISVNDLDSGINGKVICTIS----NDSPFALTPSLKDKMFSLVTKSALDR 1270 Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 E +DL A D G SS + + + D+ND+ P F TFYISE + GT++ Sbjct: 1271 EQRDKYDLTITAKDAGQLSLSSEKTITVVVSDVNDNRPEFSLSPYTFYISEANQPGTSVF 1330 Query: 708 EIRAHDPDEGPNAVVHYSI-KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYEL 765 ++A D D+ NA V Y I + G N S S+ +++ + D+E+ + ++++ Sbjct: 1331 SVKAFDRDDNDNAHVSYHILRDGSPENKLSSFLSINSETGDILALKSFDFEAQKTFQFQV 1390 Query: 766 VIR-AASPPLWNDVRVEILVTDVNDNAPVM 794 V + SP L ++V V++ + D NDNAPV+ Sbjct: 1391 VASDSGSPSLSSNVTVKVFILDQNDNAPVI 1420 Score = 289 bits (708), Expect = 1e-75 Identities = 245/890 (27%), Positives = 397/890 (44%), Gaps = 60/890 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 Q+ V D ND+SP F + + E +G ++ ++ ATD D+ +NA + Y+I Sbjct: 321 QVQVSDINDNSPRFIQNPLQFYLVENNVAGASIFSVSATDNDVSENAVISYSIA-----R 375 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 LN V ++ +G + S D E + + V A+D SP Sbjct: 376 LND-------------VTSFLNVNSENGQISALKSFDFETLKTFQFQVVASDSGSP---S 419 Query: 130 LSSTATIHVNIIDDNDNYPQF----SEKTYTVSVDE-DISVTDNPVIAKIKATDADVGAN 184 LSS T++V I+D NDN P S V+E +V ++ K++A DAD+G N Sbjct: 420 LSSNVTVNVFILDQNDNAPVILYPVSSNGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYN 479 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 + +++ + F D + L K LD E S++L + A DGG P++S ++ Sbjct: 480 GWLLFSLQQVSDHSLFGEDRKVPFLVLQKQLDRETASSHKLQLTALDGGKPAKSGAIDII 539 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 I++ DVNDN+P F L+ ++ ENVPIG ++++ A D DEG N E+ Y M K+ Sbjct: 540 IDVLDVNDNSPVFAKELYSSTIKENVPIGTVVIQINATDLDEGANGEIIY-MFGKEMDSK 598 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 + ID +G + G++D E ++L + A+D P + + Sbjct: 599 LMNVFDIDTNTGEIRVIGKIDFEESRSFELDIQASDKAQAPLTTDKSVMISVIDINDNAP 658 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQNGRGLI 423 + + ED GT V ++ +D D N ++ S + QN + Sbjct: 659 EIEVTSFSSSIKEDSKLGTTVALISVSDLDSGINGKVICSLKEDSPFNLSPSLQNNMYAV 718 Query: 424 TVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFED 481 LD + +Y LT+ A D+G + + + ++D N+ +P F ++ Y V E+ Sbjct: 719 VTRSQLDREIVSKYDLTIVAKDTGEPTFLTEKTISLIVSDVNDNSPKFLSSSYGFYVTEN 778 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 G +V V A+D D NA ITY + E + + A+ IN +TG I K D Sbjct: 779 NSPGASVFSVKASDCDENNNAMITYHIRRERTLD--ANFASFLNINSETGDIFALKSFDF 836 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT-------ANIMEDA 594 ET+ + V A D G PSLS V + ++D NDN PV + + I + Sbjct: 837 ETLKTFQFQVVASDSGSPSLSSNVTVNVFILDQNDNAPVILYPVSSNGSAEGVEEIPRNV 896 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654 G V++V A DAD+G NG + + L + + F +D +G IRT ++ A H Sbjct: 897 NAGHLVTKVRAYDADIGYNGWLLFSLQ-QVSDHSLFGLDRYTGQIRTLRSFTETDEAEHK 955 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR-AHD 713 L + D G S+T V +K+ + SD + + + +++ A D Sbjct: 956 LVILVKDNGNVSLSATATVMVKL--VEPKEAFAASDLQSSAKDDEDMLAGARFQLKGAQD 1013 Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETR-QGSDK--AELVTMVDLDYESPRKKYELVIRA- 769 D G +V HY + D F LE + +G D LV LD E+ + LV+ A Sbjct: 1014 ADSGRFSVQHYKLSQND---HFRLEVKDRGKDGKIPILVVQKSLDRET-AGSHSLVLTAL 1069 Query: 770 --ASPPLWNDVRVEILVTDVNDNAPVM-KDFQIIFNNYKDCFPVGPFGRVPAYDAD--VT 824 PP ++ + I V D+NDNAPV KD + + +V A DAD Sbjct: 1070 DGGKPPKSGEMNILINVLDINDNAPVFSKDVYSVMLHENTLIGTTVI-QVNATDADDGPN 1128 Query: 825 DKLQYRILSGNNANLILL---NETTGSMTLSPQLNTNVPKLATMEVSVTD 871 ++ Y + N N++ L NE TG +T+ ++ + +EV +D Sbjct: 1129 GEVVYSFSNSMNQNVLDLFDINEITGEITVKGPIDYEENERYEIEVEASD 1178 Score = 288 bits (706), Expect = 2e-75 Identities = 224/809 (27%), Positives = 379/809 (46%), Gaps = 60/809 (7%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 ++ I VLD ND+ P F+ Y+ + E G TV + A DQD G N E+EY++ Sbjct: 107 LNVSIIVLDNNDNIPRFDKDTYQIEISENVPVGRTVTKVSAIDQDEGANGEIEYSL---- 162 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 + TL V D+F ++ +G + + LD E+ Y + ++A+D+ +P Sbjct: 163 SKTL------------VRNVYDIFELNPLNGEIRLKGMLDFEESETYKLDIEASDKGTP- 209 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 S + V +ID + + S+ T TV D VI+ I +D D G N Sbjct: 210 --PFRSRCRVIVKVIDVKSSRNR-SDITNTVPEDS----KPGTVISLISVSDKDSGVNGK 262 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 I + I + + S+V LD E Y ++I+A D G P S + Sbjct: 263 I-ISRITSDVPFELKPSYKENTYSIVTKAFLDREMTSHYEIIIQAVDCGEPPLSTVRSIQ 321 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + + D+NDN+PRF + Q + EN G SI V A D D NA ++Y++ + Sbjct: 322 VQVSDINDNSPRFIQNPLQFYLVENNVAGASIFSVSATDNDVSENAVISYSIA---RLND 378 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 V + ++ +G + D ET +Q V A+D G P S+ T Sbjct: 379 VTSFLNVNSENGQISALKSFDFETLKTFQFQVVASDSGSPSLSSNVTVNVFILDQNDNAP 438 Query: 365 XFM-----PGQYE--VELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSIT 415 + G E E+ + G V + A DAD + L + + + F Sbjct: 439 VILYPVSSNGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQQVSDHSLFG-- 496 Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAP 473 + + + LD + + L ++A D G +S + I++ D N+ +PVF Sbjct: 497 EDRKVPFLVLQKQLDRETASSHKLQLTALDGGKPAKSGAIDIIIDVLDVNDNSPVFAKEL 556 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 Y++++ E+ PIGT V+ ++ATD D G N +I Y E+ ++ + F I+ TG I Sbjct: 557 YSSTIKENVPIGTVVIQINATDLDEGANGEIIYMFGKEMDSKLM----NVFDIDTNTGEI 612 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593 +D E + L + A D L+ V ISV+D+NDN P + ++++I ED Sbjct: 613 RVIGKIDFEESRSFELDIQASDKAQAPLTTDKSVMISVIDINDNAPEIEVTSFSSSIKED 672 Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA----SGVIRTNKALDRES 649 + +GT+V+ + +D D G+NG++ L +E+ F + P+ + T LDRE Sbjct: 673 SKLGTTVALISVSDLDSGINGKVICSL----KEDSPFNLSPSLQNNMYAVVTRSQLDREI 728 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 V+ +DL VA D G P + + + + D+ND+ P F S FY++EN+ G ++ + Sbjct: 729 VSKYDLTIVAKDTGEPTFLTEKTISLIVSDVNDNSPKFLSSSYGFYVTENNSPGASVFSV 788 Query: 710 RAHDPDEGPNAVVHYSIKGGD--DSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELV 766 +A D DE NA++ Y I+ D+N F+ S+ ++ + D+E+ + ++++V Sbjct: 789 KASDCDENNNAMITYHIRRERTLDAN-FASFLNINSETGDIFALKSFDFETLKTFQFQVV 847 Query: 767 IR-AASPPLWNDVRVEILVTDVNDNAPVM 794 + SP L ++V V + + D NDNAPV+ Sbjct: 848 ASDSGSPSLSSNVTVNVFILDQNDNAPVI 876 Score = 276 bits (677), Expect = 6e-72 Identities = 205/675 (30%), Positives = 330/675 (48%), Gaps = 51/675 (7%) Query: 98 ALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTV 157 +++T+A LDRE + Y ++++A D P LS+ +I V + D NDN P+F + Sbjct: 285 SIVTKAFLDREMTSHYEIIIQAVDCGEP---PLSTVRSIQVQVSDINDNSPRFIQNPLQF 341 Query: 158 SVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQF-SIDSLSGDVSLVKTLD 216 + E+ +V + + + ATD DV N+ I Y+I N F +++S +G +S +K+ D Sbjct: 342 YLVEN-NVAGASIFS-VSATDNDVSENAVISYSIARLNDVTSFLNVNSENGQISALKSFD 399 Query: 217 YEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ-------ESVSEN 269 +E +++++ + A D GSPS S+ + + I D NDNAP + E + N Sbjct: 400 FETLKTFQFQVVASDSGSPSLSSNVTVNVFILDQNDNAPVILYPVSSNGSAEGVEEIPRN 459 Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTM---TDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326 V G+ + +V+AYDAD G N L +++ +D G D + ++ QLDR Sbjct: 460 VNAGHLVTKVRAYDADIGYNGWLLFSLQQVSDHSLFGE-------DRKVPFLVLQKQLDR 512 Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386 ET + ++L +TA DGG P +S F Y + E+ P GT V+ Sbjct: 513 ETASSHKLQLTALDGGKPAKSGAIDIIIDVLDVNDNSPVFAKELYSSTIKENVPIGTVVI 572 Query: 387 TLTATDADE--DNRLHY---EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441 + ATD DE + + Y + F I + G I V +DF++ R + L + Sbjct: 573 QINATDLDEGANGEIIYMFGKEMDSKLMNVFDIDTNTGE--IRVIGKIDFEESRSFELDI 630 Query: 442 SATDSGGRSDTA--MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499 A+D T V I++ D N+ AP E +++S+ ED+ +GTTV ++S +D D G Sbjct: 631 QASDKAQAPLTTDKSVMISVIDINDNAPEIEVTSFSSSIKEDSKLGTTVALISVSDLDSG 690 Query: 500 INAQITYSLSSEIS-NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558 IN ++ SL + N + + + + A+ T LDRE +S Y LT+ A+D G Sbjct: 691 INGKVICSLKEDSPFNLSPSLQNNMY-------AVVTRSQLDREIVSKYDLTIVAKDTGE 743 Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618 P+ + + V DVNDN P F Y + E+ G SV V A+D D N I Y Sbjct: 744 PTFLTEKTISLIVSDVNDNSPKFLSSSYGFYVTENNSPGASVFSVKASDCDENNNAMITY 803 Query: 619 ELDPK---DREEGSFV-IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674 + + D SF+ I+ +G I K+ D E++ T + VA D G+P SS V V+ Sbjct: 804 HIRRERTLDANFASFLNINSETGDIFALKSFDFETLKTFQFQVVASDSGSPSLSSNVTVN 863 Query: 675 IKIEDINDSPPVF----ESDCLTFYISE---NSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 + I D ND+ PV S+ + E N G + ++RA+D D G N + +S++ Sbjct: 864 VFILDQNDNAPVILYPVSSNGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQ 923 Query: 728 GGDDSNSFSLETRQG 742 D + F L+ G Sbjct: 924 QVSDHSLFGLDRYTG 938 Score = 220 bits (537), Expect = 5e-55 Identities = 162/579 (27%), Positives = 272/579 (46%), Gaps = 21/579 (3%) Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 +++ I DVND++P F + + ++E+ G A D D G+N+ TY ++ D+ Sbjct: 1 VVVEITDVNDHSPSFPETEQRFEMAEHTSPGTRFELHAARDPDTGLNSIRTYILSANDHF 60 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 G +++ + + ++ ++ LDRE K+ L+VTA DGG P RS T Sbjct: 61 G-IEMSQSDEEKTPFLVLKQSLDREKSNKHSLVVTAVDGGKPQRSGTLNVSIIVLDNNDN 119 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNG- 419 F Y++E++E+ P G V ++A D DE + + Y ++ R + I N Sbjct: 120 IPRFDKDTYQIEISENVPVGRTVTKVSAIDQDEGANGEIEYSLSKTLVRNVYDIFELNPL 179 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479 G I + LDF++ Y L + A+D G + ++ I + + T +V Sbjct: 180 NGEIRLKGMLDFEESETYKLDIEASDKGTPPFRSRCRV-IVKVIDVKSSRNRSDITNTVP 238 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 ED+ GT + ++S +D D G+N +I ++S++ E + + T +I T L Sbjct: 239 EDSKPGTVISLISVSDKDSGVNGKIISRITSDVPFELKPSYKEN------TYSIVTKAFL 292 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 DRE S Y + + A D G P LS +++ V D+NDN P F Q ++E+ + G S Sbjct: 293 DREMTSHYEIIIQAVDCGEPPLSTVRSIQVQVSDINDNSPRFIQNPLQFYLVENNVAGAS 352 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 + V ATD DV N I Y + + ++ +G I K+ D E++ T + VA Sbjct: 353 IFSVSATDNDVSENAVISYSIARLNDVTSFLNVNSENGQISALKSFDFETLKTFQFQVVA 412 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVF----ESDCLTFYISE---NSPIGTTIGEIRAH 712 D G+P SS V V++ I D ND+ PV S+ + E N G + ++RA+ Sbjct: 413 SDSGSPSLSSNVTVNVFILDQNDNAPVILYPVSSNGSAEGVEEIPRNVNAGHLVTKVRAY 472 Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP 772 D D G N + +S++ D + F E R+ L +D + S K + P Sbjct: 473 DADIGYNGWLLFSLQQVSDHSLFG-EDRK-VPFLVLQKQLDRETASSHKLQLTALDGGKP 530 Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811 + + I V DVNDN+PV ++ + K+ P+G Sbjct: 531 AKSGAIDIIIDVLDVNDNSPVFAK-ELYSSTIKENVPIG 568 >UniRef50_A7RI52 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 4697 Score = 318 bits (782), Expect = 1e-84 Identities = 332/1239 (26%), Positives = 538/1239 (43%), Gaps = 135/1239 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V+D NDH+P F M+ YE + E + GT ++ + A D D G+ V Y+ L Sbjct: 2516 VTVIDVNDHTPTFNMETYECRIFENSPVGTGIIRVHAEDLDTGR---VTYS--------L 2564 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +P F ID + G + DRE+ +RY++ ATD SP Sbjct: 2565 HPSRDYQK-----------FTIDTQRGTIRNAVVFDREEESRYSLTAIATDAGSPP---F 2610 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+ + ++++D ND P F +K SV ED + + + K D+D+ ++++ + Sbjct: 2611 STQVFVKIDVLDANDQPPSFPDKNLQASVREDAPIGSS--VYKAVILDSDMVFDTSMHFF 2668 Query: 191 IIGGNTQMQFSI------DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 I GGN + +F + S G V ++ LDYE R ++L + DG + S+ L Sbjct: 2669 ISGGNEKHKFRVVTVTQQSSFYGLVEVIGRLDYETQREFKLRLTISDGKT---SDFGFLT 2725 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG-VNAELTYTMTDKDYTG 303 I + D NDNAP F +++ S+ E P G S+V V A D D V +TY++ D G Sbjct: 2726 IKVTDANDNAPLFSKLVYEVSLREESPAGTSVVTVSAIDIDSPPVQEAITYSI---DKRG 2782 Query: 304 NVDLPITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 + I +G + LDRE Y V A+DG + R+ Sbjct: 2783 --EQYFRISSSTGEITCGASPLDREKLLYYFFTVYASDGKNQGRAEVMVTLVDINDQAP- 2839 Query: 363 XXXFMPGQ-YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG-- 419 F P Y L E+ GT V + A D D+ N GGNT+ +S+ NG Sbjct: 2840 ---FFPNPPYYAALFENRAIGTNVTVMQAIDNDDPN------AGGNTKIIYSLEDNNGGY 2890 Query: 420 ------RGLITVAQPLDFK--QERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVF 469 GL+T + +D + QE + +TV ATD G S T ++Q+ D N++ P F Sbjct: 2891 VTIDSSSGLVTSIKMVDREALQEDSFKVTVRATDQGQPALSGTTVLQVFFEDENDHKPKF 2950 Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 Y ASV E G V V ATD D G N + Y + NE A F I P+ Sbjct: 2951 VRQYYYASVSESTRTGVAVTRVEATDEDTGYNGMMNYFIVQ--GNEPYA-----FFIEPR 3003 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFKQQLYT 587 TG + + +LD E+ Y L V D G+P L + V +++ D N + P F Q+++ Sbjct: 3004 TGVVRVSGILDFESKKSYELIVMVSDMGMPQLLADNLAYVFVNITDDNTHPPRFAQKVHE 3063 Query: 588 ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI-----DPASGVIRTN 642 A++ ED +G SV + ATD D H L EE F I + + +I Sbjct: 3064 ASVREDVPLGYSVLTIKATDIDTV--DSFHRFLISSGDEENMFTITESESEKMTAIITVR 3121 Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 LDRE + +++ V D T QS IV I + D ND+ P F+ + ++ EN Sbjct: 3122 GKLDRERKSFYNMIVVVND--TSGQSDECIVKITVTDANDNGPHFQPSYFSGFVRENIDS 3179 Query: 703 GTTIGEIRAHDPDEGPNA-VVHYSIKGGDDSNSFSL-ETRQGSDKAELVTMVDLDYESPR 760 + I A DPD N +++ S+ F + ++ S+ A++ D E Sbjct: 3180 EQFVTTISATDPDMPSNGPPFTFTLINTKQSSQFRIKDSTVTSNTAQVFAYGTFDREL-T 3238 Query: 761 KKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVP 817 Y+L++ A+ P +WN + + V DVN++ P+ + II N F G GR Sbjct: 3239 PFYKLLVNASDSGRPAMWNHTYIYVDVLDVNEHEPIDGNNTIIVNALDGAFAGGVIGRPY 3298 Query: 818 AYDADVTDKLQ-YRILSGNNANLILLNETTGSMTLSP--QLNTNVPKLATME-VSVTD-G 872 D D + Y++ S + + +N TG++T SP L V K + +E V D Sbjct: 3299 YQDDDYNGDINVYKMTSQSPGAYLDMNSATGAITASPGIPLGEYVVKASVIESVPRQDKA 3358 Query: 873 VNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDG-LAAIIPCPKENI 931 ++ ++ VR ++ + +L S T+RL DM + ++ LA I P++++ Sbjct: 3359 PKTVETTTRVVVRNVSTQAVLASTTMRLTDMRKPGLFVQDYYYTVERLLAGIFGVPRDHV 3418 Query: 932 YIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLA- 990 IF +Q + ++ ++ + R + V + ++ +T L + Sbjct: 3419 VIFGIQQNQTTLPSV-DIQLAIRENQGFLSV----------DTISAKIMNKKTQLTSIGL 3467 Query: 991 TVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGF 1050 V + D C + L+ C TV + AS F D + P S T + Sbjct: 3468 NVDTVRIDK--CSGDRTLS-GVCTTVTE--PASTFRVVDGDYGQVPAPAESLTIVSMDVT 3522 Query: 1051 TGVNCETILTK-ASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCELRARS 1109 + E+++ + +C + C + C G+LC+ C + + C+ RS Sbjct: 3523 HRASYESLIPEPKNC---SSSNPCLNNGICHDIFPSGVLCE-C--EPKFRGPYCQETTRS 3576 Query: 1110 FPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNE-----RHDFLALELVSSEA 1164 F +S++ +K + +F T+ + GL+LY G + DFLA+ L S Sbjct: 3577 FKGNSYIWLKTMKAFPGNDFEFEFITKESDGLMLYQGPLTDLPAWVPRDFLAVMLTSGY- 3635 Query: 1165 GRGGGPGLRFSFSLGGG--KSEITVEGNVGDGSWHTVEI 1201 + S SLG +T + DG WH ++I Sbjct: 3636 -------VTVSISLGSTPVSLNMTRGPTLNDGEWHHLKI 3667 Score = 307 bits (754), Expect = 3e-81 Identities = 242/800 (30%), Positives = 381/800 (47%), Gaps = 58/800 (7%) Query: 9 QQINVLDCND-HSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 Q + V+D P+FE Y SVRE A+ GTT+ ++A Q+ N + Y Sbjct: 2405 QTLVVIDVTTVEPPMFERHLYNISVRENAAVGTTIGQIRAVSQN---NRPIMYQ-----P 2456 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 NP ++ I+ +G+++T + LD E V Y + A + ++ S Sbjct: 2457 LHENPN------------AKEEIGIEIDTGSIVTSSKLDYESVNNYELQFVAVETSTDKS 2504 Query: 128 DRLS-STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 + L ST ++V +ID ND+ P F+ +TY + E+ V I ++ A D D G Sbjct: 2505 ETLLFSTCFVNVTVIDVNDHTPTFNMETYECRIFENSPVGTG--IIRVHAEDLDTGR--- 2559 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 + Y++ +F+ID+ G + D E+ Y L A D GSP S + I+ Sbjct: 2560 VTYSLHPSRDYQKFTIDTQRGTIRNAVVFDREEESRYSLTAIATDAGSPPFSTQVFVKID 2619 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + D ND P F Q SV E+ PIG S+ + D+D + + + ++ + Sbjct: 2620 VLDANDQPPSFPDKNLQASVREDAPIGSSVYKAVILDSDMVFDTSMHFFISGGNEKHKFR 2679 Query: 307 LPITIDPRS---GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 + +T+ +S G V G+LD ETQ +++L +T +DG S Sbjct: 2680 V-VTVTQQSSFYGLVEVIGRLDYETQREFKLRLTISDG---KTSDFGFLTIKVTDANDNA 2735 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGR--FSITSQNGRG 421 F YEV L E+ P GT VVT++A D D + RG F I+S G Sbjct: 2736 PLFSKLVYEVSLREESPAGTSVVTVSAIDIDSPPVQEAITYSIDKRGEQYFRISSSTGE- 2794 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 + A PLD ++ Y TV A+D G A V + + D N+ AP F N PY A++FE+ Sbjct: 2795 ITCGASPLDREKLLYYFFTVYASD-GKNQGRAEVMVTLVDINDQAPFFPNPPYYAALFEN 2853 Query: 482 APIGTTVLVVSATDSD---VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 IGT V V+ A D+D G N +I YSL ++ I+ +G +T+ K+ Sbjct: 2854 RAIGTNVTVMQAIDNDDPNAGGNTKIIYSLED--------NNGGYVTIDSSSGLVTSIKM 2905 Query: 539 LDRETMS--GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 +DRE + + +TV A D G P+LS TT +++ D ND++P F +Q Y A++ E Sbjct: 2906 VDREALQEDSFKVTVRATDQGQPALSGTTVLQVFFEDENDHKPKFVRQYYYASVSESTRT 2965 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 G +V++V ATD D G NG ++Y + + E +F I+P +GV+R + LD ES +++L Sbjct: 2966 GVAVTRVEATDEDTGYNGMMNYFI-VQGNEPYAFFIEPRTGVVRVSGILDFESKKSYELI 3024 Query: 657 AVAIDGGTPP--QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 + D G P + V + I D N PP F + E+ P+G ++ I+A D Sbjct: 3025 VMVSDMGMPQLLADNLAYVFVNITDDNTHPPRFAQKVHEASVREDVPLGYSVLTIKATDI 3084 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK-YELVIRAASPP 773 D ++ + I GD+ N F++ T S+K + V + RK Y +++ Sbjct: 3085 DT-VDSFHRFLISSGDEENMFTI-TESESEKMTAIITVRGKLDRERKSFYNMIVVVNDTS 3142 Query: 774 LWND-VRVEILVTDVNDNAP 792 +D V+I VTD NDN P Sbjct: 3143 GQSDECIVKITVTDANDNGP 3162 Score = 264 bits (647), Expect = 2e-68 Identities = 231/812 (28%), Positives = 384/812 (47%), Gaps = 66/812 (8%) Query: 87 QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146 Q+ F+ID +G + + L Y + VKATD SP + S ++ V++I Sbjct: 907 QNRFQIDSSTGTITSTNLLAANN--EYKLTVKATDTGSPP---MESQVSVTVSVITPITT 961 Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206 +F+E Y ++ E + V N V+ ++ AT +AI Y+I+GGN F ID + Sbjct: 962 PVKFAEANYAKTIQESL-VIGNSVL-QVTATGP-----AAITYSIVGGNKNDAFRIDRTT 1014 Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQ-DGGSPSRSNTTQLLINIRDVNDNAPRF--YTSLFQ 263 G +++ K LDYE ++SY L +RA + +P + + I + DVNDN+P F Y++ Sbjct: 1015 GQIAVNKPLDYEVLQSYVLNVRATCETYTPKIAAEVAVAITLTDVNDNSPVFLLYSNPTT 1074 Query: 264 ESVSENVP----------IGYSIV--RVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311 +V+ P Y ++ + A DAD + Y++ + DLP ++ Sbjct: 1075 VTVNSYTPEQTVVFKARRFTYYVIYEKALAVDADSESFGTVRYSINSASSNPSSDLPFSL 1134 Query: 312 DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371 D SG + T+ + +A+Y + + ATDGG +T T F +Y Sbjct: 1135 DASSGQMKTTRVIKYSDRAEYTVALVATDGGG---KSTTTSLVIKVFNINEPPKFPQPKY 1191 Query: 372 EVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431 E + E++ GT + +TAT AD + L Y IT GN F + N +G+I++A+ LD Sbjct: 1192 EFSVPENKQVGTEIGAITATYADPNTLLKYSITRGNIDDTFCV---NSKGVISLAKALD- 1247 Query: 432 KQERRYVLTVSATDSGGRSD-TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 E + T+ A S G S+ T +VQI + D N+ P+ E Y V ED GT ++ Sbjct: 1248 -SETKASFTLDAMVSHGTSNHTTVVQITVNDINDNWPIMEPV-YNVEVREDQAPGTELVK 1305 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550 V ATD D G+ ITY++ I + + F +N TG IT + LD E ++ ++L Sbjct: 1306 VVATDLDGGVGGTITYTI---IQTQDIG-SSSLFAVNASTGVITLVQKLDAEDINKHVLY 1361 Query: 551 VTARDGG-VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 V A DGG P + T V + V DVND+ P F Y A++ + V V QV ATDAD Sbjct: 1362 VKAEDGGPTPKYAAITKVVVLVGDVNDHAPRFSSSQYLASVPYEFPVNFHVFQVIATDAD 1421 Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ-- 667 G N + Y + E+G F I+ +G++ + L + H L A D G P + Sbjct: 1422 SGSNAELTYAI-TGGNEDGIFKINSENGLVSLARPLASSAKIKHKLSLKATDNGVPRRIG 1480 Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 +ST+IV + + D+ P F L + E G + ++ + ++ Y I Sbjct: 1481 TSTIIVFVILADL---LPKFPVSPLIVNVKEGVLPGGRVTTVKMTS-----SRLMTYRIL 1532 Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND-VRVEILVTD 786 G+D F +++ G +L+ + +LDYE R + + I+ D V + + + D Sbjct: 1533 EGNDEGYFRMDSLSG----DLLALKELDYEDVR-TFTMRIKGQDTDGNADVVTLVVNLED 1587 Query: 787 VNDNAPVMK---DFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLILL 842 VND +PV +++ + G P ++ YD D D+L + LS + + Sbjct: 1588 VNDCSPVFAGEVGGEVMLRVEEPFLVAGVPVVKLDVYDKDAGDRLTFE-LSDEGERIFTI 1646 Query: 843 NETTGSMTLSPQLNTNVPKLATMEVSVTDGVN 874 ++ G + + +N ++ + + V+V D + Sbjct: 1647 DD-EGQLIPTRSVN-DITEPLSFTVTVRDSAS 1676 Score = 253 bits (620), Expect = 5e-65 Identities = 250/910 (27%), Positives = 406/910 (44%), Gaps = 88/910 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I++ + ND+ P F + +V E GT++L + ATD D K+ Sbjct: 1986 IHLKNINDNYPRFTKSLFTTAVNEDVPVGTSILQVTATDCDCSKSC------------LC 2033 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P + D+F I +G + SLD E + ++VK D+ + + Sbjct: 2034 APGELTYSIDNT-----DMFAISPDTGVISPAVSLDYEMSSWVVLVVKVEDKGGS-PNIM 2087 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S A I ++ NDN P F++ Y + E V + +A + ATD D I Y Sbjct: 2088 QSYANI--TLLPVNDNSPVFAQSNYAFQISETAEVGNE--LAFVTATDRD---GDPITYT 2140 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I G + + ID SG ++L + V Y ++A DG + TT +L++I D Sbjct: 2141 IEGDSGP--YIIDPSSGIITLSREAPVN-VWEYNFKVKATDGIFTA---TTDVLLDIIDQ 2194 Query: 251 NDNAPRFY----TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 N++ P+F +S + ++EN+P G +++VQA D D G+N E+ Y + G D Sbjct: 2195 NNHKPQFTNCGESSRTVKEIAENLPSGQVLMQVQATDEDRGLNGEVEYELV----IGFTD 2250 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX- 365 +ID +G + T LDRE +K ++V A DGG Sbjct: 2251 F--SIDNTTGVIKTRYPLDRERTSKQYIVVRAKDGGHRRNELFRNINYCLIIVSVVDAND 2308 Query: 366 ----FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421 F +Y + + P G +V + A D D + E T +F+I + G Sbjct: 2309 NYPLFHIHRYVSSVYQKAPVGHSLVRVKAIDLDTGSNAKVEYTFVEPSDKFAI--EKTTG 2366 Query: 422 LITVAQPLD---------FKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENA 472 ++TV L + +TVS + R +V I++T P+FE Sbjct: 2367 IVTVKTDLSSFTGFVTLQVQSSNPVPITVSVGEDD-RDRQTLVVIDVTTVE--PPMFERH 2423 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 Y SV E+A +GTT+ + A + N I Y E N ++ I TG+ Sbjct: 2424 LYNISVRENAAVGTTIGQIRAVSQN---NRPIMYQPLHENPNAK-----EEIGIEIDTGS 2475 Query: 533 ITTNKLLDRETMSGYLLTV----TARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588 I T+ LD E+++ Y L T+ D L T V ++V+DVND+ P F + Y Sbjct: 2476 IVTSSKLDYESVNNYELQFVAVETSTDKSETLLFSTCFVNVTVIDVNDHTPTFNMETYEC 2535 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648 I E++ VGT + +V A D D G R+ Y L P R+ F ID G IR DRE Sbjct: 2536 RIFENSPVGTGIIRVHAEDLDTG---RVTYSLHPS-RDYQKFTIDTQRGTIRNAVVFDRE 2591 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 + + L A+A D G+PP S+ V V I + D ND PP F L + E++PIG+++ + Sbjct: 2592 EESRYSLTAIATDAGSPPFSTQVFVKIDVLDANDQPPSFPDKNLQASVREDAPIGSSVYK 2651 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLET-RQGSDKAELVTMVD-LDYESPRKKYELV 766 D D + +H+ I GG++ + F + T Q S LV ++ LDYE+ R +++L Sbjct: 2652 AVILDSDMVFDTSMHFFISGGNEKHKFRVVTVTQQSSFYGLVEVIGRLDYETQR-EFKLR 2710 Query: 767 IRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVG-PFGRVPAYDAD-- 822 + + + + I VTD NDNAP+ ++++ + ++ P G V A D D Sbjct: 2711 LTISDGKTSDFGFLTIKVTDANDNAPLFS--KLVYEVSLREESPAGTSVVTVSAIDIDSP 2768 Query: 823 -VTDKLQYRILSGNNANLILLNETTGSMTL-SPQLNTNVPKLATMEVSVTDGVNEIKAMM 880 V + + Y I ++ +TG +T + L+ V +DG N+ +A + Sbjct: 2769 PVQEAITYSI-DKRGEQYFRISSSTGEITCGASPLDREKLLYYFFTVYASDGKNQGRAEV 2827 Query: 881 QLSVRLITEE 890 +++ I ++ Sbjct: 2828 MVTLVDINDQ 2837 Score = 246 bits (602), Expect = 7e-63 Identities = 235/873 (26%), Positives = 385/873 (44%), Gaps = 91/873 (10%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 + I +L ND+SPVF Y + E A G + + ATD+D + YTIE Sbjct: 2090 YANITLLPVNDNSPVFAQSNYAFQISETAEVGNELAFVTATDRD---GDPITYTIE---G 2143 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 D+ P + ID SG ++T + V Y VKATD Sbjct: 2144 DS-GP-----------------YIIDPSSG-IITLSREAPVNVWEYNFKVKATDGI---- 2180 Query: 128 DRLSSTATIHVNIIDDNDNYPQFS---EKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184 ++T + ++IID N++ PQF+ E + TV + ++ V+ +++ATD D G N Sbjct: 2181 --FTATTDVLLDIIDQNNHKPQFTNCGESSRTVKEIAE-NLPSGQVLMQVQATDEDRGLN 2237 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS-----N 239 + Y ++ G T FSID+ +G + LD E+ +V+RA+DGG N Sbjct: 2238 GEVEYELVIGFTD--FSIDNTTGVIKTRYPLDRERTSKQYIVVRAKDGGHRRNELFRNIN 2295 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 +++++ D NDN P F+ + SV + P+G+S+VRV+A D D G NA++ YT + Sbjct: 2296 YCLIIVSVVDANDNYPLFHIHRYVSSVYQKAPVGHSLVRVKAIDLDTGSNAKVEYTFVEP 2355 Query: 300 DYTGNVDLPI-TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358 ++ + ++ +G + + Q+ + +T + G D T Sbjct: 2356 SDKFAIEKTTGIVTVKTDLSSFTGFVTLQVQSSNPVPITVSVGEDDRDRQTLV---VIDV 2412 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR-LHYEITGGNTRGRFSITSQ 417 F Y + + E+ GT + + A ++NR + Y+ N + I + Sbjct: 2413 TTVEPPMFERHLYNISVRENAAVGTTIGQIRA--VSQNNRPIMYQPLHENPNAKEEIGIE 2470 Query: 418 NGRGLITVAQPLDFKQERRYVLT-VSATDSGGRSDTAM-----VQINITDANNYAPVFEN 471 G I + LD++ Y L V+ S +S+T + V + + D N++ P F Sbjct: 2471 IDTGSIVTSSKLDYESVNNYELQFVAVETSTDKSETLLFSTCFVNVTVIDVNDHTPTFNM 2530 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 Y +FE++P+GT ++ V A D D G ++TYSL + Q+F I+ Q G Sbjct: 2531 ETYECRIFENSPVGTGIIRVHAEDLDTG---RVTYSLHP-------SRDYQKFTIDTQRG 2580 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 I + DRE S Y LT A D G P S V+I V+D ND P F + A++ Sbjct: 2581 TIRNAVVFDREEESRYSLTAIATDAGSPPFSTQVFVKIDVLDANDQPPSFPDKNLQASVR 2640 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS-----GVIRTNKALD 646 EDA +G+SV + D+D+ + +H+ + + + V+ G++ LD Sbjct: 2641 EDAPIGSSVYKAVILDSDMVFDTSMHFFISGGNEKHKFRVVTVTQQSSFYGLVEVIGRLD 2700 Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706 E+ L+ DG T S + IK+ D ND+ P+F + E SP GT++ Sbjct: 2701 YETQREFKLRLTISDGKT---SDFGFLTIKVTDANDNAPLFSKLVYEVSLREESPAGTSV 2757 Query: 707 GEIRAHDPDEGP-NAVVHYSI-KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764 + A D D P + YSI K G+ S T + + A + L Y Y Sbjct: 2758 VTVSAIDIDSPPVQEAITYSIDKRGEQYFRISSSTGEITCGASPLDREKLLY------YF 2811 Query: 765 LVIRAASPPLWNDVRVEILVT--DVNDNAPVMKD---FQIIFNNYKDCFPVGPFGRVPAY 819 + A+ N R E++VT D+ND AP + + +F N V + Sbjct: 2812 FTVYASDGK--NQGRAEVMVTLVDINDQAPFFPNPPYYAALFENRAIGTNVTVMQAIDND 2869 Query: 820 D--ADVTDKLQYRILSGNNANLILLNETTGSMT 850 D A K+ Y L NN + ++ ++G +T Sbjct: 2870 DPNAGGNTKIIYS-LEDNNGGYVTIDSSSGLVT 2901 Score = 217 bits (531), Expect = 3e-54 Identities = 230/855 (26%), Positives = 371/855 (43%), Gaps = 103/855 (12%) Query: 11 INVLDCNDHSPVFE-MQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 I+V+D ND+ P F + + + + + +G+ VL+L A D D +N EV + I Sbjct: 1779 ISVIDVNDNVPRFTGITRIYKRINKNSLNGSPVLSLNALDLDYERNGEVGFQIV------ 1832 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 P D F I+ + T +L++E Y V A D P + Sbjct: 1833 --PRDGP-------------FGINPVDEMIETTGNLNKES---YEFDVYAFDYGIPRLNS 1874 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + +HV + Y E + +I +KA + + I Y Sbjct: 1875 TTIPMVVHVAEVPPIFEVLDNDHNMYRFETAE--TSHGGELIGTVKAVSY---SKALIAY 1929 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYE-QVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 I GN + F I +L+G++ ++YE Y L + A + ++I+++ Sbjct: 1930 EITSGNVRNSFKIGTLTGEIRHNNFMNYEIHENVYNLTVTASELIPRGHQTEIPVIIHLK 1989 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN-----AELTYTMTDKDYTG 303 ++NDN PRF SLF +V+E+VP+G SI++V A D D + ELTY++ + D Sbjct: 1990 NINDNYPRFTKSLFTTAVNEDVPVGTSILQVTATDCDCSKSCLCAPGELTYSIDNTDM-- 2047 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 I P +G + + LD E + L+V D G P + Sbjct: 2048 -----FAISPDTGVISPAVSLDYEMSSWVVLVVKVEDKGGSPNIMQSYANITLLPVNDNS 2102 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423 F Y +++E G + +TATD D D + Y I G + G + I +G + Sbjct: 2103 PVFAQSNYAFQISETAEVGNELAFVTATDRDGD-PITYTIEGDS--GPYIIDPSSGIITL 2159 Query: 424 TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA----SVF 479 + P++ + Y V ATD G + T V ++I D NN+ P F N ++ + Sbjct: 2160 SREAPVNVWE---YNFKVKATD-GIFTATTDVLLDIIDQNNHKPQFTNCGESSRTVKEIA 2215 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E+ P G ++ V ATD D G+N ++ Y L + D F I+ TG I T L Sbjct: 2216 ENLPSGQVLMQVQATDEDRGLNGEVEYEL-------VIGFTD--FSIDNTTGVIKTRYPL 2266 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVE-----ISVVDVNDNEPVFKQQLYTANIMEDA 594 DRE S + V A+DGG ++ +SVVD NDN P+F Y +++ + A Sbjct: 2267 DRERTSKQYIVVRAKDGGHRRNELFRNINYCLIIVSVVDANDNYPLFHIHRYVSSVYQKA 2326 Query: 595 LVGTSVSQVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGVIRTNKALDRES---- 649 VG S+ +V A D D G N ++ Y ++P D+ F I+ +G++ L + Sbjct: 2327 PVGHSLVRVKAIDLDTGSNAKVEYTFVEPSDK----FAIEKTTGIVTVKTDLSSFTGFVT 2382 Query: 650 --VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 V + + + + G + +V I + + PP+FE + EN+ +GTTIG Sbjct: 2383 LQVQSSNPVPITVSVGEDDRDRQTLVVIDVTTV--EPPMFERHLYNISVRENAAVGTTIG 2440 Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 +IRA + P +++ + ++ E D +VT LDYES YEL Sbjct: 2441 QIRAVSQNNRP--IMYQPLHENPNAKE---EIGIEIDTGSIVTSSKLDYESV-NNYELQF 2494 Query: 768 RAASPP-------LWNDVRVEILVTDVNDNAPV--MKDFQI-IFNNYKDCFPVGP-FGRV 816 A L++ V + V DVND+ P M+ ++ IF N PVG RV Sbjct: 2495 VAVETSTDKSETLLFSTCFVNVTVIDVNDHTPTFNMETYECRIFEN----SPVGTGIIRV 2550 Query: 817 PAYDADVTDKLQYRI 831 A D D T ++ Y + Sbjct: 2551 HAEDLD-TGRVTYSL 2564 Score = 208 bits (508), Expect = 2e-51 Identities = 197/734 (26%), Positives = 318/734 (43%), Gaps = 57/734 (7%) Query: 2 SVPFC--IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVE 59 S PF + +I+VLD ND P F + +ASVRE A G++V D D+ + + Sbjct: 2607 SPPFSTQVFVKIDVLDANDQPPSFPDKNLQASVREDAPIGSSVYKAVILDSDMVFDTSMH 2666 Query: 60 YTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKA 119 + I V V + G + LD E + + + Sbjct: 2667 FFI-------------SGGNEKHKFRVVTVTQQSSFYGLVEVIGRLDYETQREFKLRLTI 2713 Query: 120 TDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA 179 +D + S + + + D NDN P FS+ Y VS+ E+ S V+ + A D Sbjct: 2714 SD------GKTSDFGFLTIKVTDANDNAPLFSKLVYEVSLREE-SPAGTSVVT-VSAIDI 2765 Query: 180 D-VGANSAIRYAIIGGNTQMQFSIDSLSGDVSL-VKTLDYEQVRSYRLVIRAQDGGSPSR 237 D AI Y+ I + F I S +G+++ LD E++ Y + A DG + R Sbjct: 2766 DSPPVQEAITYS-IDKRGEQYFRISSSTGEITCGASPLDREKLLYYFFTVYASDGKNQGR 2824 Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE---GVNAELTY 294 + ++++ + D+ND AP F + ++ EN IG ++ +QA D D+ G N ++ Y Sbjct: 2825 A---EVMVTLVDINDQAPFFPNPPYYAALFENRAIGTNVTVMQAIDNDDPNAGGNTKIIY 2881 Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET--QAKYQLLVTATDGGDPPRSATATX 352 ++ D + G +TID SG V + +DRE + +++ V ATD G P S T Sbjct: 2882 SLEDNN--GGY---VTIDSSSGLVTSIKMVDREALQEDSFKVTVRATDQGQPALSGTTVL 2936 Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRG 410 F+ Y ++E G V + ATD D + ++Y I GN Sbjct: 2937 QVFFEDENDHKPKFVRQYYYASVSESTRTGVAVTRVEATDEDTGYNGMMNYFIVQGNEPY 2996 Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG----RSDTAMVQINITDANNYA 466 F I + G++ V+ LDF+ ++ Y L V +D G + A V +NITD N + Sbjct: 2997 AFFIEPRT--GVVRVSGILDFESKKSYELIVMVSDMGMPQLLADNLAYVFVNITDDNTHP 3054 Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 P F + ASV ED P+G +VL + ATD D +++ + +SS +E + Sbjct: 3055 PRFAQKVHEASVREDVPLGYSVLTIKATDIDT-VDSFHRFLISS--GDEENMFTITESES 3111 Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586 T IT LDRE S Y + V D SD V+I+V D NDN P F+ + Sbjct: 3112 EKMTAIITVRGKLDRERKSFYNMIVVVND--TSGQSDECIVKITVTDANDNGPHFQPSYF 3169 Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK--- 643 + + E+ V+ + ATD D+ NG ++ F I ++ T + Sbjct: 3170 SGFVRENIDSEQFVTTISATDPDMPSNGPPFTFTLINTKQSSQFRIKDSTVTSNTAQVFA 3229 Query: 644 --ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701 DRE + L A D G P + +++ + D+N+ P+ ++ + + + Sbjct: 3230 YGTFDRELTPFYKLLVNASDSGRPAMWNHTYIYVDVLDVNEHEPIDGNNTIIVNALDGAF 3289 Query: 702 IGTTIGEIRAHDPD 715 G IG D D Sbjct: 3290 AGGVIGRPYYQDDD 3303 Score = 207 bits (506), Expect = 3e-51 Identities = 186/688 (27%), Positives = 316/688 (45%), Gaps = 63/688 (9%) Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV--IAKIKATDADVGANSAIRY 189 + T+ V I D N+ P F Y +V E S D V + A D D G S+ Y Sbjct: 103 TATTLLVTIKDSNNFLPTFGSSVYNGTVMEG-SKEDTVVKGLENCHAEDRDTGGISS--Y 159 Query: 190 AIIGGNTQMQFSIDSLS-GDVSLVKTLDYE------QVRSYRLVIRAQDGGSPSRSNTTQ 242 II GN + F +++ G+ ++ L + + +LV+ A+D GSP+R+ TTQ Sbjct: 160 TIISGNEKGYFKTSTINVGEERFLQILTTDLPITRDTTNTIKLVVEARDSGSPARTVTTQ 219 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 + I++ + N+N P+F + V E + + RV A D D+G++ + Y Y Sbjct: 220 IHISVENRNENTPKFEKEEYTAMVMEETQLNSPVARVHAKDTDQGMSGSVYY------YL 273 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT------------A 350 + T++P +G V G LD + Q+ YQL V ATD G P R A + Sbjct: 274 SPLSSYFTVNPITGVVILVGTLDYQKQSSYQLTVMATDRGSPRREAATKVILTIKDSQFS 333 Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGN 407 F + ED P V TATD D + RL Y ++G Sbjct: 334 PPADSADPGANTAPVFTRKALATTVREDLPKNGFVFLATATDNDPPGPNQRLLYSLSGPE 393 Query: 408 TRGRFSITSQNGRGLITVAQPLDFKQERRYV-LTVSATDSGGRSDTA----MVQINITDA 462 G F+I + ++T+A LD+++ + LTV+ATD G + +A +V I D Sbjct: 394 A-GLFAIDPDS--AVVTLAAALDYEKGPTVINLTVTATDQGSPALSASAPLIVYIKDVDE 450 Query: 463 NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522 N PVF+ SV ED +GT++ ATD D G + ++ YS+ ++ E V + Sbjct: 451 NQNLPVFDPKAQAISVKEDTALGTSIFTAKATDEDSGPDGELEYSM---VAGEGVGY--- 504 Query: 523 QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582 ++N TG +TT + DR+T + + A D G + + I V V+D P F Sbjct: 505 -VILNETTGVVTTAAMFDRKTNPVVEVVIAAHDKGTFPRTSKFYLLIQVEKVDDMYPEFT 563 Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642 Q Y+A +++ + T V + ATD + N +I Y L + F ++ ++GVIRT Sbjct: 564 QPAYSATVLDGSPENTFVVALHATDYE---NTQIEYRLVNVGVND-LFQVERSTGVIRTA 619 Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 + ++ + + I+ + + +V+I I+ + P F + + ENS Sbjct: 620 RE-PAKTRGDQEFNQLIIEASDKTRQAITLVNILIKSTKEVVPRFTTSAFEIKVPENSGP 678 Query: 703 GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762 ++ + A D D G + YSI GG + F+++ Q S K ++ D + E+ Sbjct: 679 FDSLVCLAATDGDLGS---ITYSITGG-GNGKFAVD--QHSGKFSVLRSFDYELEN---G 729 Query: 763 YELVIRAASP-PLWNDVRVEILVTDVND 789 Y + ++A +P + V++++++++D Sbjct: 730 YIVQVQAETPNAKTSSANVKLIISNIDD 757 Score = 198 bits (484), Expect = 1e-48 Identities = 189/687 (27%), Positives = 311/687 (45%), Gaps = 62/687 (9%) Query: 52 IGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA 111 + +N +V I +TA +P + + D F ++ + L +A LD E A Sbjct: 1195 VPENKQVGTEIGAITATYADP-NTLLKYSITRGNIDDTFCVNSKGVISLAKA-LDSETKA 1252 Query: 112 RYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVI 171 +T+ + S + T + + + D NDN+P E Y V V ED + + Sbjct: 1253 SFTLDAMVSHGTS------NHTTVVQITVNDINDNWP-IMEPVYNVEVREDQA--PGTEL 1303 Query: 172 AKIKATDADVGANSAIRYAIIG----GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVI 227 K+ ATD D G I Y II G++ + F++++ +G ++LV+ LD E + + L + Sbjct: 1304 VKVVATDLDGGVGGTITYTIIQTQDIGSSSL-FAVNASTGVITLVQKLDAEDINKHVLYV 1362 Query: 228 RAQDGG-SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE 286 +A+DGG +P + T++++ + DVND+APRF +S + SV P+ + + +V A DAD Sbjct: 1363 KAEDGGPTPKYAAITKVVVLVGDVNDHAPRFSSSQYLASVPYEFPVNFHVFQVIATDADS 1422 Query: 287 GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR 346 G NAELTY +T GN D I+ +G V + L + K++L + ATD G P R Sbjct: 1423 GSNAELTYAITG----GNEDGIFKINSENGLVSLARPLASSAKIKHKLSLKATDNGVPRR 1478 Query: 347 SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG 406 T+T F V + E PG V T+ T + + Y I G Sbjct: 1479 IGTST-IIVFVILADLLPKFPVSPLIVNVKEGVLPGGRVTTVKMTSS---RLMTYRILEG 1534 Query: 407 NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYA 466 N G F + S +G + + LD++ R + + + D+ G +D + +N+ D N+ + Sbjct: 1535 NDEGYFRMDSLSGD--LLALKELDYEDVRTFTMRIKGQDTDGNADVVTLVVNLEDVNDCS 1592 Query: 467 PVFENAPYTASVFE-DAPI---GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522 PVF + + P G V+ + D D G ++T+ LS E ++ Sbjct: 1593 PVFAGEVGGEVMLRVEEPFLVAGVPVVKLDVYDKDAG--DRLTFELSDE--------GER 1642 Query: 523 QFVINPQTGAITTNKLLD-RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581 F I+ + I T + D E +S TVT RD P ++ V ++ + + PV Sbjct: 1643 IFTIDDEGQLIPTRSVNDITEPLS---FTVTVRDSASPPHVTSSRVTLNFEKLGEALPV- 1698 Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641 + + EDA +G V+ V +I Y DP +F ID G IR Sbjct: 1699 -----ESRVREDAYIGMIVTFVPKVFPKSVF--KITYPKDP------AFSIDEI-GDIRV 1744 Query: 642 NKALDRESVATHDLKAVAIDG-GTPPQSSTVIVHIKIEDINDSPPVFESDCLTF-YISEN 699 K LD E ++ L + G+ P+ +V I + D+ND+ P F + I++N Sbjct: 1745 AKPLDFEKQVSYTLTVREAESIGSSPRVFDRVVVISVIDVNDNVPRFTGITRIYKRINKN 1804 Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSI 726 S G+ + + A D D N V + I Sbjct: 1805 SLNGSPVLSLNALDLDYERNGEVGFQI 1831 Score = 197 bits (481), Expect = 3e-48 Identities = 240/891 (26%), Positives = 383/891 (42%), Gaps = 112/891 (12%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 QI V D ND+ P+ E Y VRE + GT ++ + ATD D G + YTI Sbjct: 1272 QITVNDINDNWPIME-PVYNVEVREDQAPGTELVKVVATDLDGGVGGTITYTI------- 1323 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + +D +F ++ +G + LD E + ++ + VKA D P Sbjct: 1324 IQTQDIGSSS---------LFAVNASTGVITLVQKLDAEDINKHVLYVKAED-GGPTPKY 1373 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + T + V + D ND+ P+FS Y SV + V N + ++ ATDAD G+N+ + Y Sbjct: 1374 AAITKVV-VLVGDVNDHAPRFSSSQYLASVPYEFPV--NFHVFQVIATDADSGSNAELTY 1430 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 AI GGN F I+S +G VSL + L ++L ++A D G P R T+ +++ + Sbjct: 1431 AITGGNEDGIFKINSENGLVSLARPLASSAKIKHKLSLKATDNGVPRRIGTSTIIVFVI- 1489 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 + D P+F S +V E V G + V+ + +TY + + GN + Sbjct: 1490 LADLLPKFPVSPLIVNVKEGVLPGGRVTTVKMTSS-----RLMTYRILE----GNDEGYF 1540 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 +D SG + +LD E + + + G D +A G Sbjct: 1541 RMDSLSGDLLALKELDYEDVRTFTMRIK---GQDTDGNADVVTLVVNLEDVNDCSPVFAG 1597 Query: 370 QY--EVELAEDEP---PGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG----R 420 + EV L +EP G PVV L D D +RL +E++ R F+I + R Sbjct: 1598 EVGGEVMLRVEEPFLVAGVPVVKLDVYDKDAGDRLTFELSDEGER-IFTIDDEGQLIPTR 1656 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 + + +PL F TV+ DS ++ + N+ + E P + V E Sbjct: 1657 SVNDITEPLSF--------TVTVRDSASPPHVTSSRVTL----NFEKLGEALPVESRVRE 1704 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 DA IG V V +ITY D F I+ + G I K LD Sbjct: 1705 DAYIGMIVTFVPKVFPKSVF--KITYP------------KDPAFSID-EIGDIRVAKPLD 1749 Query: 541 RETMSGYLLTVTARD--GGVPSLSDTTDVEISVVDVNDNEPVFK--QQLYTANIMEDALV 596 E Y LTV + G P + D V ISV+DVNDN P F ++Y I +++L Sbjct: 1750 FEKQVSYTLTVREAESIGSSPRVFDRV-VVISVIDVNDNVPRFTGITRIYK-RINKNSLN 1807 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 G+ V + A D D NG + +++ P+D G F I+P +I T L++ES ++ Sbjct: 1808 GSPVLSLNALDLDYERNGEVGFQIVPRD---GPFGINPVDEMIETTGNLNKES---YEFD 1861 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE-----SDCLTFYISENSPIGTTIGEIRA 711 A D G P +ST I + + + PP+FE + F +E S G IG ++A Sbjct: 1862 VYAFDYGIPRLNSTTIP--MVVHVAEVPPIFEVLDNDHNMYRFETAETSHGGELIGTVKA 1919 Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771 + A++ Y I G+ NSF + T G E+ ++YE Y L + A+ Sbjct: 1920 VSYSK---ALIAYEITSGNVRNSFKIGTLTG----EIRHNNFMNYEIHENVYNLTVTASE 1972 Query: 772 -PPLWNDVRVEILV--TDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVT--- 824 P + + +++ ++NDN P + + PVG +V A D D + Sbjct: 1973 LIPRGHQTEIPVIIHLKNINDNYPRFTK-SLFTTAVNEDVPVGTSILQVTATDCDCSKSC 2031 Query: 825 ----DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 +L Y I +N ++ ++ TG ++ + L+ + + V V D Sbjct: 2032 LCAPGELTYSI---DNTDMFAISPDTGVISPAVSLDYEMSSWVVLVVKVED 2079 Score = 176 bits (429), Expect = 6e-42 Identities = 223/931 (23%), Positives = 390/931 (41%), Gaps = 102/931 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+V + N+++P FE ++Y A V E + V + A D D G + V Y L Sbjct: 222 ISVENRNENTPKFEKEEYTAMVMEETQLNSPVARVHAKDTDQGMSGSVYYY--------L 273 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +P + F ++ +G ++ +LD +K + Y + V ATD+ SP + Sbjct: 274 SP-------------LSSYFTVNPITGVVILVGTLDYQKQSSYQLTVMATDRGSPRREAA 320 Query: 131 SSTA-TIH-------VNIIDDNDNY-PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181 + TI + D N P F+ K +V ED+ N + ATD D Sbjct: 321 TKVILTIKDSQFSPPADSADPGANTAPVFTRKALATTVREDLP--KNGFVFLATATDNDP 378 Query: 182 -GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY-RLVIRAQDGGSPSRSN 239 G N + Y++ G + F+ID S V+L LDYE+ + L + A D GSP+ S Sbjct: 379 PGPNQRLLYSLSGPEAGL-FAIDPDSAVVTLAAALDYEKGPTVINLTVTATDQGSPALSA 437 Query: 240 TTQLLINIRDV--NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297 + L++ I+DV N N P F SV E+ +G SI +A D D G + EL Y+M Sbjct: 438 SAPLIVYIKDVDENQNLPVFDPKAQAISVKEDTALGTSIFTAKATDEDSGPDGELEYSMV 497 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357 + G V L T +G V T+ DR+T ++++ A D G PR++ Sbjct: 498 AGEGVGYVILNET----TGVVTTAAMFDRKTNPVVEVVIAAHDKGTFPRTSKFYLLIQVE 553 Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ 417 F Y + + P T VV L ATD E+ ++ Y + F + Sbjct: 554 KVDDMYPEFTQPAYSATVLDGSPENTFVVALHATDY-ENTQIEYRLVNVGVNDLFQVERS 612 Query: 418 NGRGLITVAQPLDFKQERRY-VLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA 476 G + T +P + ++ + L + A+D ++ T +V I I P F + + Sbjct: 613 TGV-IRTAREPAKTRGDQEFNQLIIEASDKTRQAIT-LVNILIKSTKEVVPRFTTSAFEI 670 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 V E++ +++ ++ATD D+G ITYS++ + + F ++ +G + Sbjct: 671 KVPENSGPFDSLVCLAATDGDLG---SITYSITGGGNGK--------FAVDQHSGKFSVL 719 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 + D E +GY++ V A + S + IS +D + P F + YT + E Sbjct: 720 RSFDYELENGYIVQVQAETPNAKTSSANVKLIISNID---DLPSFAKPEYTLTVPEGTTP 776 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 GT++ G +G + D + G +++ S + + ++R + + Sbjct: 777 GTTILD--------GSSGFQFVDDDTNPEQFGCSLMEVTSMFVLEHFRVERSD---SECR 825 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY---ISENSPIGTTIGEIRAHD 713 I S T + ++ N + P ++ Y +S ++P T I + A D Sbjct: 826 LTVIKSLFEHHSVTQFTFL-VQVTNKAFPNIQATAKASYWATVSSDTPTRTPIVTVTASD 884 Query: 714 PD--EGPNAVVHYSIKGGDDS--NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 D EG V+ + D S N F +++ G T+ + + +Y+L ++A Sbjct: 885 LDKEEGNQQVLFQFVSDADSSGQNRFQIDSSTG-------TITSTNLLAANNEYKLTVKA 937 Query: 770 A---SPPLWNDVRVEI-LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD 825 SPP+ + V V + ++T + PV ++ +G V A Sbjct: 938 TDTGSPPMESQVSVTVSVITPIT--TPVKFAEANYAKTIQESLVIG--NSVLQVTATGPA 993 Query: 826 KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVR 885 + Y I+ GN + ++ TTG + ++ L+ V + + V T K +++V Sbjct: 994 AITYSIVGGNKNDAFRIDRTTGQIAVNKPLDYEVLQSYVLNVRATCETYTPKIAAEVAVA 1053 Query: 886 LITEEM-------LL--NSITVRLNDMTAEQ 907 + ++ LL N TV +N T EQ Sbjct: 1054 ITLTDVNDNSPVFLLYSNPTTVTVNSYTPEQ 1084 Score = 167 bits (407), Expect = 3e-39 Identities = 190/722 (26%), Positives = 304/722 (42%), Gaps = 76/722 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLK---ATDQDIGKNAEVEYTIELVTA 67 + + D N+ P F Y +V EG+ T V L+ A D+D G + YTI ++ Sbjct: 109 VTIKDSNNFLPTFGSSVYNGTVMEGSKEDTVVKGLENCHAEDRDTGGISS--YTI--ISG 164 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 + E + +I L T + R+ ++V+A D SP Sbjct: 165 N----EKGYFKTSTINVGEERFLQI------LTTDLPITRDTTNTIKLVVEARDSGSPAR 214 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 + T IH+++ + N+N P+F ++ YT V E+ + N +A++ A D D G + ++ Sbjct: 215 ---TVTTQIHISVENRNENTPKFEKEEYTAMVMEETQL--NSPVARVHAKDTDQGMSGSV 269 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 Y + F+++ ++G V LV TLDY++ SY+L + A D GSP R T++++ I Sbjct: 270 YYYL--SPLSSYFTVNPITGVVILVGTLDYQKQSSYQLTVMATDRGSPRREAATKVILTI 327 Query: 248 RDVN------------DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTY 294 +D + AP F +V E++P + A D D G N L Y Sbjct: 328 KDSQFSPPADSADPGANTAPVFTRKALATTVREDLPKNGFVFLATATDNDPPGPNQRLLY 387 Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET-QAKYQLLVTATDGGDPPRSATATXX 353 +++ + G IDP S V + LD E L VTATD G P SA+A Sbjct: 388 SLSGPE-AG----LFAIDPDSAVVTLAAALDYEKGPTVINLTVTATDQGSPALSASAPLI 442 Query: 354 XXXXXXXXXXX--XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTR 409 F P + + ED GT + T ATD D D L Y + G Sbjct: 443 VYIKDVDENQNLPVFDPKAQAISVKEDTALGTSIFTAKATDEDSGPDGELEYSMVAGEGV 502 Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAP 467 G + I ++ G++T A D K + ++A D G R+ + I + ++ P Sbjct: 503 G-YVILNET-TGVVTTAAMFDRKTNPVVEVVIAAHDKGTFPRTSKFYLLIQVEKVDDMYP 560 Query: 468 VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527 F Y+A+V + +P T V+ + ATD + N QI Y L + N+ F + Sbjct: 561 EFTQPAYSATVLDGSPENTFVVALHATDYE---NTQIEYRLVNVGVNDL-------FQVE 610 Query: 528 PQTGAITTNK--LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585 TG I T + R L + A D + T V I + + P F Sbjct: 611 RSTGVIRTAREPAKTRGDQEFNQLIIEASD---KTRQAITLVNILIKSTKEVVPRFTTSA 667 Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645 + + E++ S+ + ATD D+ G I Y + G F +D SG ++ Sbjct: 668 FEIKVPENSGPFDSLVCLAATDGDL---GSITYSI--TGGGNGKFAVDQHSGKFSVLRSF 722 Query: 646 DRESVATHDLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 D E + V + TP ++S+ V + I +I+D P F T + E + GT Sbjct: 723 DYE---LENGYIVQVQAETPNAKTSSANVKLIISNIDDLPS-FAKPEYTLTVPEGTTPGT 778 Query: 705 TI 706 TI Sbjct: 779 TI 780 Score = 163 bits (396), Expect = 6e-38 Identities = 221/911 (24%), Positives = 377/911 (41%), Gaps = 91/911 (9%) Query: 2 SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 S P ++ I +D N + PVF+ + SV+E + GT++ T KATD+D G + E+EY+ Sbjct: 438 SAPLIVY--IKDVDENQNLPVFDPKAQAISVKEDTALGTSIFTAKATDEDSGPDGELEYS 495 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121 +V + + ++ +G + T A DR+ V++ A D Sbjct: 496 --MVAGEGVG-----------------YVILNETTGVVTTAAMFDRKTNPVVEVVIAAHD 536 Query: 122 QAS-PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD 180 + + P + + I V +D D YP+F++ Y+ +V + +N + + ATD + Sbjct: 537 KGTFPRTSKF--YLLIQVEKVD--DMYPEFTQPAYSATVLD--GSPENTFVVALHATDYE 590 Query: 181 VGANSAIRYAIIGGNTQMQFSIDSLSGDVSL----VKTLDYEQVRSYRLVIRAQDGGSPS 236 N+ I Y ++ F ++ +G + KT ++ +L+I A D + Sbjct: 591 ---NTQIEYRLVNVGVNDLFQVERSTGVIRTAREPAKTRGDQEFN--QLIIEASD---KT 642 Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 R T + I I+ + PRF TS F+ V EN S+V + A D D G +TY++ Sbjct: 643 RQAITLVNILIKSTKEVVPRFTTSAFEIKVPENSGPFDSLVCLAATDGDLG---SITYSI 699 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 TG + +D SG D E + Y + V A P ++ Sbjct: 700 -----TGGGNGKFAVDQHSGKFSVLRSFDYELENGYIVQVQAE---TPNAKTSSANVKLI 751 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITS 416 F +Y + + E PGT ++ ++ D+ + E G + +TS Sbjct: 752 ISNIDDLPSFAKPEYTLTVPEGTTPGTTILDGSSGFQFVDDDTNPEQFGCSL---MEVTS 808 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSD-TAMVQINITDANNYAPVFENAPYT 475 V + E R + S + + T +VQ+ N A Y Sbjct: 809 MFVLEHFRVERS---DSECRLTVIKSLFEHHSVTQFTFLVQVTNKAFPNIQAT-AKASYW 864 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGI-NAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 A+V D P T ++ V+A+D D N Q+ + S+ + +F I+ TG IT Sbjct: 865 ATVSSDTPTRTPIVTVTASDLDKEEGNQQVLFQFVSDADSSG----QNRFQIDSSTGTIT 920 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 + LL + Y LTV A D G P + V +SV+ F + Y I E Sbjct: 921 STNLL--AANNEYKLTVKATDTGSPPMESQVSVTVSVITPITTPVKFAEANYAKTIQESL 978 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654 ++G SV QV AT I Y + ++ + +F ID +G I NK LD E + ++ Sbjct: 979 VIGNSVLQVTATGP-----AAITYSIVGGNKND-AFRIDRTTGQIAVNKPLDYEVLQSYV 1032 Query: 655 LKAVA-IDGGTPPQSSTVIVHIKIEDINDSPPVF--ESDCLTFYISENSPIGTTIGEIR- 710 L A + TP ++ V V I + D+ND+ PVF S+ T ++ +P T + + R Sbjct: 1033 LNVRATCETYTPKIAAEVAVAITLTDVNDNSPVFLLYSNPTTVTVNSYTPEQTVVFKARR 1092 Query: 711 -----------AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759 A D D V YSI + S L + ++ T + Y S Sbjct: 1093 FTYYVIYEKALAVDADSESFGTVRYSINSASSNPSSDLPFSLDASSGQMKTTRVIKY-SD 1151 Query: 760 RKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPA 818 R +Y + + A+ +++ N N P + + VG G + A Sbjct: 1152 RAEYTVAL-VATDGGGKSTTTSLVIKVFNINEPPKFPQPKYEFSVPENKQVGTEIGAITA 1210 Query: 819 YDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKA 878 AD L+Y I GN + +N + G ++L+ L++ T++ V+ G + Sbjct: 1211 TYADPNTLLKYSITRGNIDDTFCVN-SKGVISLAKALDSETKASFTLDAMVSHGTSNHTT 1269 Query: 879 MMQLSVRLITE 889 ++Q++V I + Sbjct: 1270 VVQITVNDIND 1280 Score = 157 bits (382), Expect = 3e-36 Identities = 141/563 (25%), Positives = 249/563 (44%), Gaps = 42/563 (7%) Query: 206 SGDVSLVKTLDYE--QVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263 +G V+ K +Y + ++ L I + T LL+ I+D N+ P F +S++ Sbjct: 68 AGVVTSAKPFEYRIGESNTFTLTIVKRQRSQVFGGTATTLLVTIKDSNNFLPTFGSSVYN 127 Query: 264 ESVSENVP---IGYSIVRVQAYDADEG-VNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319 +V E + + A D D G +++ + +K Y + + + + Sbjct: 128 GTVMEGSKEDTVVKGLENCHAEDRDTGGISSYTIISGNEKGYFKTSTINVGEERFLQILT 187 Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE 379 T + R+T +L+V A D G P R+ T F +Y + E+ Sbjct: 188 TDLPITRDTTNTIKLVVEARDSGSPARTVTTQIHISVENRNENTPKFEKEEYTAMVMEET 247 Query: 380 PPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437 +PV + A D D+ ++Y ++ ++ F++ G ++ + LD++++ Y Sbjct: 248 QLNSPVARVHAKDTDQGMSGSVYYYLSPLSSY--FTVNPITG--VVILVGTLDYQKQSSY 303 Query: 438 VLTVSATDSGG--RSDTAMVQINITDAN------------NYAPVFENAPYTASVFEDAP 483 LTV ATD G R V + I D+ N APVF +V ED P Sbjct: 304 QLTVMATDRGSPRREAATKVILTIKDSQFSPPADSADPGANTAPVFTRKALATTVREDLP 363 Query: 484 IGTTVLVVSATDSDV-GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 V + +ATD+D G N ++ YSLS + F I+P + +T LD E Sbjct: 364 KNGFVFLATATDNDPPGPNQRLLYSLSGPEAG--------LFAIDPDSAVVTLAAALDYE 415 Query: 543 TMSGYL-LTVTARDGGVPSLSDTTDVEISVVDVNDNE--PVFKQQLYTANIMEDALVGTS 599 + LTVTA D G P+LS + + + + DV++N+ PVF + ++ ED +GTS Sbjct: 416 KGPTVINLTVTATDQGSPALSASAPLIVYIKDVDENQNLPVFDPKAQAISVKEDTALGTS 475 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 + ATD D G +G + Y + + G +++ +GV+ T DR++ ++ A Sbjct: 476 IFTAKATDEDSGPDGELEYSMVAGEGV-GYVILNETTGVVTTAAMFDRKTNPVVEVVIAA 534 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 D GT P++S + I++E ++D P F + + + SP T + + A D + N Sbjct: 535 HDKGTFPRTSKFYLLIQVEKVDDMYPEFTQPAYSATVLDGSPENTFVVALHATDYE---N 591 Query: 720 AVVHYSIKGGDDSNSFSLETRQG 742 + Y + ++ F +E G Sbjct: 592 TQIEYRLVNVGVNDLFQVERSTG 614 Score = 146 bits (354), Expect = 8e-33 Identities = 127/483 (26%), Positives = 220/483 (45%), Gaps = 47/483 (9%) Query: 421 GLITVAQPLDFK--QERRYVLTVSATDS----GGRSDTAMVQINITDANNYAPVFENAPY 474 G++T A+P +++ + + LT+ GG + T +V I D+NN+ P F ++ Y Sbjct: 69 GVVTSAKPFEYRIGESNTFTLTIVKRQRSQVFGGTATTLLVTIK--DSNNFLPTFGSSVY 126 Query: 475 TASVFEDAPIGTTVLVVS---ATDSDVGINAQITYSLSSE---ISNEAVAHHDQQFVINP 528 +V E + T V + A D D G + T +E + +++F+ Sbjct: 127 NGTVMEGSKEDTVVKGLENCHAEDRDTGGISSYTIISGNEKGYFKTSTINVGEERFL--- 183 Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588 +TT+ + R+T + L V ARD G P+ + TT + ISV + N+N P F+++ YTA Sbjct: 184 --QILTTDLPITRDTTNTIKLVVEARDSGSPARTVTTQIHISVENRNENTPKFEKEEYTA 241 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648 +ME+ + + V++V A D D G++G ++Y L P F ++P +GV+ LD + Sbjct: 242 MVMEETQLNSPVARVHAKDTDQGMSGSVYYYLSPL---SSYFTVNPITGVVILVGTLDYQ 298 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP------------PVFESDCLTFYI 696 +++ L +A D G+P + + V + I+D SP PVF L + Sbjct: 299 KQSSYQLTVMATDRGSPRREAATKVILTIKDSQFSPPADSADPGANTAPVFTRKALATTV 358 Query: 697 SENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755 E+ P + A D D GPN + YS+ G ++ F+++ D A + LD Sbjct: 359 REDLPKNGFVFLATATDNDPPGPNQRLLYSL-SGPEAGLFAID----PDSAVVTLAAALD 413 Query: 756 YESPRKKYELVIRA---ASPPLWNDVRVEILVTDV--NDNAPVM-KDFQIIFNNYKDCFP 809 YE L + A SP L + + + DV N N PV Q I Sbjct: 414 YEKGPTVINLTVTATDQGSPALSASAPLIVYIKDVDENQNLPVFDPKAQAISVKEDTALG 473 Query: 810 VGPF-GRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVS 868 F + D+ +L+Y +++G ++LNETTG +T + + + + ++ Sbjct: 474 TSIFTAKATDEDSGPDGELEYSMVAGEGVGYVILNETTGVVTTAAMFDRKTNPVVEVVIA 533 Query: 869 VTD 871 D Sbjct: 534 AHD 536 Score = 45.6 bits (103), Expect = 0.020 Identities = 35/110 (31%), Positives = 48/110 (43%), Gaps = 7/110 (6%) Query: 1245 CEIPTETCHRFLDLTG--PLQIGGLPNIPSSF-QVKNKDFVGCISDFYIDHKFIDLNSYV 1301 C+I T L L G PLQ+GG+ N S+ + FVGCI + DL+ + Sbjct: 3742 CQITGTTVGTDLVLNGVWPLQVGGVSNTELSYPSLVYTGFVGCIRNLVDFGDMYDLDKPL 3801 Query: 1302 ADNGTLAGCPEKRSRCSSAPCYNGAECS-DLWDTYICDCKEGHTGKDCAD 1350 + GC E RC PC + + C + C C G TG +C D Sbjct: 3802 VQVNSAKGC-ELAMRCP--PCGSDSYCEPQINRASYCVCNLGKTGFECKD 3848 Score = 38.3 bits (85), Expect = 3.0 Identities = 24/80 (30%), Positives = 35/80 (43%), Gaps = 8/80 (10%) Query: 1271 PSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNG--TLAGCPEKRSRCSSAPCYNGAEC 1328 P+S + K+ DF GC+SD + +D + V + GCP C C+N C Sbjct: 4157 PNSTKAKS-DFEGCVSDHRYNGYHMDKDRTVDRYQWRVIKGCP-----CEPGGCFNNGTC 4210 Query: 1329 SDLWDTYICDCKEGHTGKDC 1348 C C+ G+TG C Sbjct: 4211 MANATIPTCKCQPGYTGLTC 4230 >UniRef50_Q17LY6 Cluster: Cadherin; n=6; Culicidae|Rep: Cadherin - Aedes aegypti (Yellowfever mosquito) Length = 1653 Score = 314 bits (770), Expect = 3e-83 Identities = 369/1507 (24%), Positives = 614/1507 (40%), Gaps = 171/1507 (11%) Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 +IRY I GN F+I + +G + + K LDYE+++ Y L + D + N T +L+ Sbjct: 7 SIRYKITSGNIGDVFAIHNTTGALYVAKALDYEKIKKYELRLTVSDS---FKENYTTVLV 63 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYS--IVRVQAYDADEGVNAELTYTMTDK--DY 301 N++DVNDN P F S ++ ++E G ++RV A DAD + + Y +T D Sbjct: 64 NVKDVNDNPPVFERSSYRTQITEEDDRGLPKRVMRVTASDADVERPSNIIYFLTGPGIDI 123 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRET---QAKYQLLVTATDGGDPPRSATATXXXXXXX 358 + I+ +G ++ L+R+ + ++ V A D G Sbjct: 124 ENPSESNFDINKATGEIFVLKPLNRDPPHGRPLWKFTVFAQDEGGEGLVGFTEVQIKLKD 183 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQ 417 F G Y + E+ G V+T+ A D D+ D H +I + +I + Sbjct: 184 INDNAPSFPQGIYYGNVTENGTVGMYVMTIKAQDNDDVDEGTHAKIVYSIEKN--AIEEE 241 Query: 418 NG---------RGLITVAQP-LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAP 467 G G+IT A LD ++ Y L + ATD GG T I + D N+ P Sbjct: 242 TGLPIFDINPDTGVITTAVCCLDREKTPDYSLQIVATDGGGLKGTGTASIKVKDLNDMPP 301 Query: 468 VFENAPYTASVFE-DAPI--GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524 F + V E D I +L V+ D D N Q SS + A Sbjct: 302 HFTKDEWFVEVEETDGNILPEAPILTVTVNDDDEINNFQYKIIESSGYGADKFA----MI 357 Query: 525 VINPQTGAITTNKLLDRET---MSGYLLTVTARDG-GVPSLS----DTTDVEISVVDVND 576 N TG++ + LD E ++G+ + D G+ D + V + + D+ND Sbjct: 358 KNNDGTGSLRVVQPLDFEDPMQINGFRFRIQVTDNEGINDTDKYHVDHSWVIVKLKDIND 417 Query: 577 NEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS 636 N P F++ A E+ VG ++ A D D +I Y ++ + F I Sbjct: 418 NTPRFRRPHMEAYTSENDEVGKTLVSFKAIDIDKAGKSKITYMINRATDRKRQFSISD-E 476 Query: 637 GVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696 G + + LDRE+++ ++L+ +AID G PP+++T + ++++D+ND+ PVF + + Sbjct: 477 GTVTIQRQLDREAISKYNLEILAIDDGVPPRTATATLTVEVKDVNDNAPVFAEEYRPILL 536 Query: 697 SENSPIGTTIGEIRAHDPDE-----GPNAVVHYSIKGGD-DSNSFSLETRQGSDKAELVT 750 ENSP I EI A D D+ GP D SF +E D +V+ Sbjct: 537 -ENSPASKII-EISAIDQDDRRMENGPPFQFRMDPDADDVIRTSFKVEQNNKGDGMAVVS 594 Query: 751 MVDLDYESPRKKYE--LVIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC 807 + RK+YE +VI+ + +P + + + DVNDN +++ NY+ Sbjct: 595 SLRSFDREYRKQYEIPIVIKDSGNPAQTGTSTLTVTIGDVNDNIMQPGSKEVVVYNYQGQ 654 Query: 808 FPVGPFGRVPAYDA---DVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLAT 864 P P GRV D D +DKL Y N L++T+G +T+ KL Sbjct: 655 APDTPIGRVFVNDLDDWDTSDKLFYWDELENPR--FKLDDTSGMVTMRRGAREGRYKL-R 711 Query: 865 MEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFL-----------SPLL 913 ++ +E A M + V+ I+ E ++NS ++RL +T E F+ L Sbjct: 712 FKIYDRKHAHESHANMSVVVKHISYEAIVNSGSIRLLGITDEDFIRIWDYRTQNIFKSKL 771 Query: 914 GFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPT 973 F + LA ++ K+N+ +FSVQ + I +V FSAR + ++ Sbjct: 772 ERFREKLAELLNIDKKNVDVFSVQ-IKQKSPAITDVRFSARN-----------AYYFKAV 819 Query: 974 HLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLF 1033 L V LH+ + + + + + + C+ E C +++ VN++ Sbjct: 820 QLNGVVLLHKEDIEQAVGINITMVNIDECLVENGDCNGSCTHIMEVQANPSLVNANKTAL 879 Query: 1034 RPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCS 1093 + ++ C C N + SC+ C +G +C + G CS Sbjct: 880 VGVQIKSTAECMC-------NAREYKQQQSCK----SHPCLNGGRCSDTKSG----IRCS 924 Query: 1094 IDAAYTTAVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNG------- 1146 Y+ C+ RSF + + +P L + H+ ++F T GL+ YNG Sbjct: 925 CPPGYSGPRCQQTVRSFRGNGWAWYPSLDMCDKSHISVEFITTKAEGLIFYNGPIVPPDD 984 Query: 1147 -RYNERHDFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVE--GNVGDGSWHTVEIEY 1203 ++ DF+ALEL G P RF G G E+ ++ + DG WH +++ + Sbjct: 985 NNEQQQSDFIALEL------EQGYP--RFLIDYGSGTLELRIQTKNPLNDGDWHRIDLFW 1036 Query: 1204 FNRTITMILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQ 1263 + MI+D C + + A D + F A +P + +L+L PLQ Sbjct: 1037 DTERVKMIVDYC-RTAVITEADDGNI----VEFVDHTCQAAGRVP--QFNEYLNLNTPLQ 1089 Query: 1264 IGGLPNIPSSFQVKN-------KDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSR 1316 IGG+ + F GCI +F + DL+ T++GC + Sbjct: 1090 IGGVFREKFDYTYNRWQYMPVAAGFEGCIRNFKHNGILYDLSHPGLSKSTMSGCVFTQEV 1149 Query: 1317 CSSAP----CYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLRP 1372 C P C +C +D C+C G +G C+ T P F + + P Sbjct: 1150 CDLNPQVSKCLEHGKCIGNFDDAKCECNPGWSGTYCSLPT-TPTTFKTHSYVKYALSFEP 1208 Query: 1373 IQLPWLNALSIRTRQR--DAFVMS---------IQLKSGLLHYSY---NGET----MYLP 1414 + L RTR+ + F +S I+LK L + Y +G+ + L Sbjct: 1209 DKFTTQIQLRFRTRETFGELFRISDQHMREYGIIELKEAKLWFRYSLNSGQVEERDVSLS 1268 Query: 1415 MATLSDGAWHRIEIKWLGTDISVTVDYGLRTVLMPMLA-NKIQGQYIGK---ILIGGLDT 1470 + DG WH + I+ G+ + +D G + + Q + K + GG Sbjct: 1269 AVEVDDGQWHVVRIQRYGSAAILELDGGEGANFNQSFSFDGHQWLSVDKQEGVYAGGKPE 1328 Query: 1471 TAGLLASDV--GFFEGCIQDVRIG---------TAQSLLNRPTVRENVRDGCQSRADCML 1519 G+ +V + + CI D+R+ T + + T+ +N+ C S C Sbjct: 1329 YTGVKTFEVQADYQKSCIDDIRLDGKSLPLPPTTNGTQWGQATMAKNIERYCSSNNPCQN 1388 Query: 1520 SICPPYSKCVTSWDSSTCTCEAGRV----GPQCV--SACELGPC-GAARCVPDQTPKGYS 1572 + CP +CV W+ C C G + G C+ + C PC C+ + Y Sbjct: 1389 AYCPEPFECVDLWNKYECACGDGMIISPEGKTCIDRNECLDYPCLNGGTCINQEPRFKYK 1448 Query: 1573 CACEPGY 1579 C C Y Sbjct: 1449 CICPDSY 1455 Score = 239 bits (586), Expect = 6e-61 Identities = 190/671 (28%), Positives = 316/671 (47%), Gaps = 57/671 (8%) Query: 86 VQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145 + DVF I +GAL +LD EK+ +Y + + +D + T+ VN+ D ND Sbjct: 17 IGDVFAIHNTTGALYVAKALDYEKIKKYELRLTVSDSFK------ENYTTVLVNVKDVND 70 Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG------GNTQMQ 199 N P F +Y + E+ + ++ A+DADV S I Y + G ++ Sbjct: 71 NPPVFERSSYRTQITEEDDRGLPKRVMRVTASDADVERPSNIIYFLTGPGIDIENPSESN 130 Query: 200 FSIDSLSGDVSLVKTLDYEQVRS---YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256 F I+ +G++ ++K L+ + ++ + AQD G T++ I ++D+NDNAP Sbjct: 131 FDINKATGEIFVLKPLNRDPPHGRPLWKFTVFAQDEGGEGLVGFTEVQIKLKDINDNAPS 190 Query: 257 FYTSLFQESVSENVPIGYSIVRVQAY---DADEGVNAELTYTMTDKDYTGNVDLPI-TID 312 F ++ +V+EN +G ++ ++A D DEG +A++ Y++ LPI I+ Sbjct: 191 FPQGIYYGNVTENGTVGMYVMTIKAQDNDDVDEGTHAKIVYSIEKNAIEEETGLPIFDIN 250 Query: 313 PRSGWVYTS-GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371 P +G + T+ LDRE Y L + ATDGG T T F ++ Sbjct: 251 PDTGVITTAVCCLDREKTPDYSLQIVATDGGG--LKGTGTASIKVKDLNDMPPHFTKDEW 308 Query: 372 EVELAEDEP---PGTPVVTLTATDADEDNRLHYEI--TGGNTRGRFSITSQN-GRGLITV 425 VE+ E + P P++T+T D DE N Y+I + G +F++ N G G + V Sbjct: 309 FVEVEETDGNILPEAPILTVTVNDDDEINNFQYKIIESSGYGADKFAMIKNNDGTGSLRV 368 Query: 426 AQPLDFK---QERRYVLTVSATDSGGRSDT-------AMVQINITDANNYAPVFENAPYT 475 QPLDF+ Q + + TD+ G +DT + V + + D N+ P F Sbjct: 369 VQPLDFEDPMQINGFRFRIQVTDNEGINDTDKYHVDHSWVIVKLKDINDNTPRFRRPHME 428 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 A E+ +G T++ A D D ++ITY + N A +QF I+ + G +T Sbjct: 429 AYTSENDEVGKTLVSFKAIDIDKAGKSKITYMI-----NRA-TDRKRQFSISDE-GTVTI 481 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 + LDRE +S Y L + A D GVP + T + + V DVNDN PVF ++ Y ++E++ Sbjct: 482 QRQLDREAISKYNLEILAIDDGVPPRTATATLTVEVKDVNDNAPVFAEE-YRPILLENS- 539 Query: 596 VGTSVSQVGATDADVGL--NG-RIHYELDP--KDREEGSFVID-----PASGVIRTNKAL 645 + + ++ A D D NG + +DP D SF ++ V+ + ++ Sbjct: 540 PASKIIEISAIDQDDRRMENGPPFQFRMDPDADDVIRTSFKVEQNNKGDGMAVVSSLRSF 599 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 DRE +++ V D G P Q+ T + + I D+ND+ S + Y + T Sbjct: 600 DREYRKQYEIPIVIKDSGNPAQTGTSTLTVTIGDVNDNIMQPGSKEVVVYNYQGQAPDTP 659 Query: 706 IGEIRAHDPDE 716 IG + +D D+ Sbjct: 660 IGRVFVNDLDD 670 Score = 132 bits (319), Expect = 1e-28 Identities = 127/484 (26%), Positives = 220/484 (45%), Gaps = 54/484 (11%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQ---DIGKNAEVEYTIELVT 66 QI + D ND++P F Y +V E + G V+T+KA D D G +A++ Y+IE Sbjct: 178 QIKLKDINDNAPSFPQGIYYGNVTENGTVGMYVMTIKAQDNDDVDEGTHAKIVYSIE--- 234 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR-ASLDREKVARYTVLVKATDQASP 125 + + E +F I+ +G + T LDREK Y++ + ATD Sbjct: 235 KNAIEEETGL-----------PIFDINPDTGVITTAVCCLDREKTPDYSLQIVATDGGG- 282 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE-DISVTDNPVIAKIKATDADVGAN 184 L T T + + D ND P F++ + V V+E D ++ I + D D N Sbjct: 283 ----LKGTGTASIKVKDLNDMPPHFTKDEWFVEVEETDGNILPEAPILTVTVNDDDEINN 338 Query: 185 SAIRYAIIGGNTQMQFSI---DSLSGDVSLVKTLDYE---QVRSYRLVIRAQDGGSPSRS 238 + G +F++ + +G + +V+ LD+E Q+ +R I+ D + + Sbjct: 339 FQYKIIESSGYGADKFAMIKNNDGTGSLRVVQPLDFEDPMQINGFRFRIQVTDNEGINDT 398 Query: 239 NT-----TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293 + + +++ ++D+NDN PRF + SEN +G ++V +A D D+ +++T Sbjct: 399 DKYHVDHSWVIVKLKDINDNTPRFRRPHMEAYTSENDEVGKTLVSFKAIDIDKAGKSKIT 458 Query: 294 YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353 Y M ++ I+ + G V QLDRE +KY L + A D G PPR+ATAT Sbjct: 459 Y-MINRATDRKRQFSISDE---GTVTIQRQLDREAISKYNLEILAIDDGVPPRTATATLT 514 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE---DNRLHYEI-----TG 405 F +Y L E+ P + ++ ++A D D+ +N ++ Sbjct: 515 VEVKDVNDNAPVFAE-EYRPILLENS-PASKIIEISAIDQDDRRMENGPPFQFRMDPDAD 572 Query: 406 GNTRGRFSITSQN-GRGLITVAQPLDFKQE--RRYVLTVSATDSG--GRSDTAMVQINIT 460 R F + N G G+ V+ F +E ++Y + + DSG ++ T+ + + I Sbjct: 573 DVIRTSFKVEQNNKGDGMAVVSSLRSFDREYRKQYEIPIVIKDSGNPAQTGTSTLTVTIG 632 Query: 461 DANN 464 D N+ Sbjct: 633 DVND 636 Score = 110 bits (265), Expect = 5e-22 Identities = 138/598 (23%), Positives = 245/598 (40%), Gaps = 54/598 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSG--TTVLTLKATDQDIGKNAEVEYTIELVTAD 68 +NV D ND+ PVFE Y + E G V+ + A+D D+ + + + Y + D Sbjct: 63 VNVKDVNDNPPVFERSSYRTQITEEDDRGLPKRVMRVTASDADVERPSNIIYFLTGPGID 122 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 NP ++ F I+ +G + L+R+ + + Sbjct: 123 IENPSESN-------------FDINKATGEIFVLKPLNRDPPHGRPLWKFTVFAQDEGGE 169 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKA---TDADVGANS 185 L + + + D NDN P F + Y +V E+ +V + IKA D D G ++ Sbjct: 170 GLVGFTEVQIKLKDINDNAPSFPQGIYYGNVTENGTV--GMYVMTIKAQDNDDVDEGTHA 227 Query: 186 AIRYAIIGGNTQMQ--FSIDSLSGDVSLVKT----LDYEQVRSYRLVIRAQDGGSPSRSN 239 I Y+I + + I ++ D ++ T LD E+ Y L I A DGG + Sbjct: 228 KIVYSIEKNAIEEETGLPIFDINPDTGVITTAVCCLDREKTPDYSLQIVATDGGGLKGTG 287 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSE---NVPIGYSIVRVQAYDADEGVNAELTYTM 296 T I ++D+ND P F + V E N+ I+ V D DE +N + Sbjct: 288 TAS--IKVKDLNDMPPHFTKDEWFVEVEETDGNILPEAPILTVTVNDDDE-INNFQYKII 344 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA-----KYQLLVTATDG---GDPPRSA 348 Y + I + +G + LD E ++++ VT +G D Sbjct: 345 ESSGYGADKFAMIKNNDGTGSLRVVQPLDFEDPMQINGFRFRIQVTDNEGINDTDKYHVD 404 Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGG 406 + F E +E++ G +V+ A D D+ +++ Y I Sbjct: 405 HSWVIVKLKDINDNTPRFRRPHMEAYTSENDEVGKTLVSFKAIDIDKAGKSKITYMINRA 464 Query: 407 NTRGR-FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDAN 463 R R FSI+ + G +T+ + LD + +Y L + A D G R+ TA + + + D N Sbjct: 465 TDRKRQFSISDE---GTVTIQRQLDREAISKYNLEILAIDDGVPPRTATATLTVEVKDVN 521 Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD---VGINAQITYSLSSEISNE-AVAH 519 + APVF Y + E++P + ++ +SA D D + + + + + + Sbjct: 522 DNAPVFAE-EYRPILLENSP-ASKIIEISAIDQDDRRMENGPPFQFRMDPDADDVIRTSF 579 Query: 520 HDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577 +Q +++ + DRE Y + + +D G P+ + T+ + +++ DVNDN Sbjct: 580 KVEQNNKGDGMAVVSSLRSFDREYRKQYEIPIVIKDSGNPAQTGTSTLTVTIGDVNDN 637 Score = 89.0 bits (211), Expect = 2e-15 Identities = 87/321 (27%), Positives = 134/321 (41%), Gaps = 27/321 (8%) Query: 138 VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG-NT 196 V + D NDN P+F E+ V + KA D D S I Y I + Sbjct: 410 VKLKDINDNTPRFRRPHMEAYTSENDEV--GKTLVSFKAIDIDKAGKSKITYMINRATDR 467 Query: 197 QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256 + QFSI G V++ + LD E + Y L I A D G P R+ T L + ++DVNDNAP Sbjct: 468 KRQFSISD-EGTVTIQRQLDREAISKYNLEILAIDDGVPPRTATATLTVEVKDVNDNAPV 526 Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEG--VNAELTYTMTDKDYTGNVDLPITIDPR 314 F ++ + EN P I+ + A D D+ N D D + ++ Sbjct: 527 F-AEEYRPILLENSPAS-KIIEISAIDQDDRRMENGPPFQFRMDPDADDVIRTSFKVEQN 584 Query: 315 S---GWVYTSG--QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 + G S DRE + +Y++ + D G+P ++ T+T PG Sbjct: 585 NKGDGMAVVSSLRSFDREYRKQYEIPIVIKDSGNPAQTGTST--LTVTIGDVNDNIMQPG 642 Query: 370 QYEVEL--AEDEPPGTPVVTLTATDADE---DNRLHYEITGGNTRGRFSITSQNGRGLIT 424 EV + + + P TP+ + D D+ ++L Y N R + TS G++T Sbjct: 643 SKEVVVYNYQGQAPDTPIGRVFVNDLDDWDTSDKLFYWDELENPRFKLDDTS----GMVT 698 Query: 425 VAQPLDFKQERRYVLTVSATD 445 + + +E RY L D Sbjct: 699 MRRG---AREGRYKLRFKIYD 716 >UniRef50_Q96JQ0 Cluster: Protocadherin-16 precursor; n=12; Amniota|Rep: Protocadherin-16 precursor - Homo sapiens (Human) Length = 3298 Score = 314 bits (770), Expect = 3e-83 Identities = 253/819 (30%), Positives = 377/819 (46%), Gaps = 52/819 (6%) Query: 92 IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151 ID SG + T LDRE+ RY D A T + V + D ND+ P F Sbjct: 94 IDEHSGVVRTARVLDREQRDRYRFTAVTPDGA---------TVEVTVRVADINDHAPAFP 144 Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD--- 208 + + V E + + A DAD G YA+ G F +++ G Sbjct: 145 QARAALQVPEHTAFGTRYPLEP--ARDADAGRLGTQGYALSGDGAGETFRLETRPGPDGT 202 Query: 209 --VSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 LV T LD E Y L + A DGGSP R L + + D+ND+AP F S + Sbjct: 203 PVPELVVTGELDRENRSHYMLQLEAYDGGSPPRRAQALLDVTLLDINDHAPAFNQSRYHA 262 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 VSE++ G +++V A DAD GVN +TY + + G D P +ID +G + L Sbjct: 263 VVSESLAPGSPVLQVFASDADAGVNGAVTYEINRRQSEG--DGPFSIDAHTGLLQLERPL 320 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX----XXXXXFMPGQYEVELAEDEP 380 D E + ++L+V A DGG P +A F+ +++E P Sbjct: 321 DFEQRRVHELVVQARDGGAHPELGSAFVTVHVRDANDNQPSMTVIFLSADGSPQVSEAAP 380 Query: 381 PGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG-RGLITVAQPLDFKQERRYVL 439 PG V ++ +D D+ + H ++ G F++++Q+ L+ VA+ LD ++ Y L Sbjct: 381 PGQLVARISVSDPDDGDFAHVNVSLEGGEGHFALSTQDSVIYLVCVARRLDREERDAYNL 440 Query: 440 TVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI-GTTVLVVSATD 495 V+ATDSG R++ A V +++TD N+ AP F+ Y + + G+ V+ V+A D Sbjct: 441 RVTATDSGSPPLRAEAAFV-LHVTDVNDNAPAFDRQLYRPEPLPEVALPGSFVVRVTARD 499 Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555 D G N Q+TYSL A H F I+P +G ITT LD E L V A D Sbjct: 500 PDQGTNGQVTYSL-------APGAHTHWFSIDPTSGIITTAASLDYELEPQPQLIVVATD 552 Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615 GG+P L+ + V +++ DVNDNEP F++ Y A++ E GT QV ATDAD G G Sbjct: 553 GGLPPLASSATVSVALQDVNDNEPQFQRTFYNASLPEGTQPGTCFLQVTATDADSGPFGL 612 Query: 616 IHYELDPKDREEGS--FVIDPASGVIRTNKALDR-ESVATHDLKAVAIDGGTPPQSSTVI 672 + Y L GS F ID SG + T + LDR + ++ D A+DGG S V Sbjct: 613 LSYSLGAGLGSSGSPPFRIDAHSGDVCTTRTLDRDQGPSSFDFTVTAVDGG--GLKSMVY 670 Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732 V + + D ND+PP F IS SP GT + +RAHDPD+G + + Y I G+ Sbjct: 671 VKVFLSDENDNPPQFYPREYAASISAQSPPGTAVLRLRAHDPDQGSHGRLSYHILAGNSP 730 Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVND 789 F+L+ + G L+T+ +L I A RV+I + Sbjct: 731 PLFTLDEQSG-----LLTVAWPLARRANSVVQLEIGAEDGGGLQAEPSARVDISIVPGTP 785 Query: 790 NAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD-ADVTDKLQYRILSGNNANLILLNETTGS 848 P+ + Q +F+ +D P G V A++ + + G+ L L+ +G Sbjct: 786 TPPIFEQLQYVFSVPEDVAPGTSVGIVQAHNPPGRLAPVTLSLSGGDPRGLFSLDAVSGL 845 Query: 849 M-TLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886 + TL P + + +EV GV A+ ++ V L Sbjct: 846 LQTLRPLDRELLGPVLELEVRAGSGVPPAFAVARVRVLL 884 Score = 310 bits (762), Expect = 3e-82 Identities = 257/812 (31%), Positives = 391/812 (48%), Gaps = 82/812 (10%) Query: 11 INVLDCNDHSPVFEMQQYEAS------VREGASSGTTVLTLKATDQDIGKNAEVEYTIEL 64 + VLD ND+SP F A V + GT V TL+A D D G+N + YT+ Sbjct: 1199 VAVLDLNDNSPTFLQASGAAGGGLPIQVPDRVPPGTLVTTLQAKDPDEGENGTILYTLT- 1257 Query: 65 VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS 124 P ++F + SG LLT A L R + Y + + A DQ S Sbjct: 1258 ------GPGS-------------ELFSLHPHSGELLTAAPLIRAERPHYVLTLSAHDQGS 1298 Query: 125 PVSDRLSSTATIHVNIIDD---NDNYPQFSEKTYTVSVDEDISVT------DNPVIAKIK 175 P S++ + V ++ + P +E+ V ++VT ++ + Sbjct: 1299 PPR---SASLQLLVQVLPSARLAEPPPDLAERDPAAPVPVVLTVTAAEGLRPGSLLGSVA 1355 Query: 176 ATD-ADVGANSAIRYAIIGG-NTQMQFSIDSLSGDVSLVKTLDYEQVRSYR-LVIRAQ-D 231 A + A VG A+ Y ++GG + + F++D+ SG + L + LD+E +R L +RA+ Sbjct: 1356 APEPAGVG---ALTYTLVGGADPEGTFALDAASGRLYLARPLDFEAGPPWRALTVRAEGP 1412 Query: 232 GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNA 290 GG+ +R Q + ++D N++AP F ++ EN G ++ +A DAD G N+ Sbjct: 1413 GGAGARLLRVQ--VQVQDENEHAPAFARDPLALALPENPEPGAALYTFRASDADGPGPNS 1470 Query: 291 ELTYTMTDKDYTGNVDLP-ITIDPRSGWVYTSGQLDRETQAKYQLLVTATD--GGDPPRS 347 ++ Y + ++ +P + +D R+G + LDRET LLV ATD R Sbjct: 1471 DVRYRLLRQE----PPVPALRLDARTGALSAPRGLDRETTPALLLLVEATDRPANASRRR 1526 Query: 348 ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITG 405 A V L ED+PPG + + A D D E R+ Y + Sbjct: 1527 AARVSARVFVTDENDNAPVFASPSRVRLPEDQPPGPAALHVVARDPDLGEAARVSYRLAS 1586 Query: 406 GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDAN 463 G G F + S G ++V +PLD +Q +VLTV A+D G RS T ++ +++ D N Sbjct: 1587 GGD-GHFRLHSST--GALSVVRPLDREQRAEHVLTVVASDHGSPPRSATQVLTVSVADVN 1643 Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523 + AP F+ Y+ + E+ P GT++L + ATD DVG N Q+TY +S+E+ Sbjct: 1644 DEAPTFQQQEYSVLLRENNPPGTSLLTLRATDPDVGANGQVTY---GGVSSES------- 1693 Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583 F ++P TG +TT + LDRE LTV A+D G P V ++V D ND+ P F Sbjct: 1694 FSLDPDTGVLTTLRALDREEQEEINLTVYAQDRGSPPQLTHVTVRVAVEDENDHAPTFGS 1753 Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK 643 + + E T ++ + A+D DVG NG++ Y + D G+FV+D ASG T + Sbjct: 1754 AHLSLEVPEGQDPQT-LTMLRASDPDVGANGQLQYRILDGD-PSGAFVLDLASGEFGTMR 1811 Query: 644 ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703 LDRE L+ A DGG P S+T+++ + + D ND P F + + E+ P G Sbjct: 1812 PLDREVEPAFQLRIEARDGGQPALSATLLLTVTVLDANDHAPAFPVPAYSVEVPEDVPAG 1871 Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES-PRKK 762 T + +++AHDPD G N V Y + G + +F LE G EL T LD E P Sbjct: 1872 TLLLQLQAHDPDAGANGHVTYYL-GAGTAGAFLLEPSSG----ELRTAAALDREQCPSYT 1926 Query: 763 YEL--VIRAASPPLWNDVRVEILVTDVNDNAP 792 + + V AA+ PL V V I V DVND+AP Sbjct: 1927 FSVSAVDGAAAGPLSTTVSVTITVRDVNDHAP 1958 Score = 305 bits (749), Expect = 1e-80 Identities = 241/793 (30%), Positives = 359/793 (45%), Gaps = 66/793 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 ++V D ND +P F+ Q+Y +RE GT++LTL+ATD D+G N +V Y Sbjct: 1637 VSVADVNDEAPTFQQQEYSVLLRENNPPGTSLLTLRATDPDVGANGQVTY---------- 1686 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F +D +G L T +LDRE+ + V A D+ SP Sbjct: 1687 ------------GGVSSESFSLDPDTGVLTTLRALDREEQEEINLTVYAQDRGSPPQ--- 1731 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + T+ V + D+ND+ P F ++ V E D + ++A+D DVGAN ++Y Sbjct: 1732 LTHVTVRVAVEDENDHAPTFGSAHLSLEVPEG---QDPQTLTMLRASDPDVGANGQLQYR 1788 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I+ G+ F +D SG+ ++ LD E +++L I A+DGG P+ S T L + + D Sbjct: 1789 ILDGDPSGAFVLDLASGEFGTMRPLDREVEPAFQLRIEARDGGQPALSATLLLTVTVLDA 1848 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 ND+AP F + V E+VP G ++++QA+D D G N +TY + G Sbjct: 1849 NDHAPAFPVPAYSVEVPEDVPAGTLLLQLQAHDPDAGANGHVTYYLG----AGTAG-AFL 1903 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSATATXXXXXXXXXXXXXXFMPG 369 ++P SG + T+ LDRE Y V+A DG P S T + F Sbjct: 1904 LEPSSGELRTAAALDREQCPSYTFSVSAVDGAAAGPLSTTVSVTITVRDVNDHAPTFPTS 1963 Query: 370 QYEVELAEDEP----PGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLI 423 + L P P + TL A D D + + Y + G G T + G I Sbjct: 1964 PLRLRLPRPGPSFSTPTLALATLRAEDRDAGANASILYRLAGTPPPG---TTVDSYTGEI 2020 Query: 424 TVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 VA+ R VL + ATD G RS T ++ + + P F A A++ E+ Sbjct: 2021 RVARSPVALGPRDRVLFIVATDLGRPARSATGVIIVGLQGEAERGPRFPRASSEATIREN 2080 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL--L 539 AP GT ++ A + G N ITYS+ S NE F I P TGAIT L Sbjct: 2081 APPGTPIVSPRAVHAG-GTNGPITYSILS--GNE-----KGTFSIQPSTGAITVRSAEGL 2132 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 D E L + A GG + T + +++ D NDN P F + Y A + E + Sbjct: 2133 DFEVSPRLRLVLQAESGGAFAF---TVLTLTLQDANDNAPRFLRPHYVAFLPESRPLEGP 2189 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 + QV A D D G G+I Y L G F +DP +G I T LDRE A L +A Sbjct: 2190 LLQVEADDLDQGSGGQISYSLAASQPARGLFHVDPTTGTITTTAILDREIWAETRLVLMA 2249 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 D G+P + + + + D ND+ P +SE++ +G+ I ++ +D D GP Sbjct: 2250 TDRGSPALVGSATLTVMVIDTNDNRPTIPQP-WELRVSEDALLGSEIAQVTGNDVDSGP- 2307 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR 779 V+ Y + + FS+ G + LD+E +Y+L + A P Sbjct: 2308 -VLWYVLSPSGPQDPFSV----GRYGGRVSLTGPLDFEQ-CDRYQLQLLAHDGPHEGRAN 2361 Query: 780 VEILVTDVNDNAP 792 + +LV DVNDNAP Sbjct: 2362 LTVLVEDVNDNAP 2374 Score = 300 bits (737), Expect = 3e-79 Identities = 234/786 (29%), Positives = 361/786 (45%), Gaps = 46/786 (5%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + +LD NDH+P F +Y A V E + G+ VL + A+D D G N V Y I ++ Sbjct: 243 VTLLDINDHAPAFNQSRYHAVVSESLAPGSPVLQVFASDADAGVNGAVTYEINRRQSEGD 302 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P F ID +G L LD E+ + ++V+A D + + Sbjct: 303 GP-----------------FSIDAHTGLLQLERPLDFEQRRVHELVVQARDGGAH-PELG 344 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP--VIAKIKATDADVGANSAIR 188 S+ T+HV D NDN P + + +S P ++A+I +D D G + + Sbjct: 345 SAFVTVHVR--DANDNQPSMTVIFLSADGSPQVSEAAPPGQLVARISVSDPDDGDFAHVN 402 Query: 189 YAIIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 ++ GG S DS+ V + + LD E+ +Y L + A D GSP ++++ Sbjct: 403 VSLEGGEGHFALSTQDSVIYLVCVARRLDREERDAYNLRVTATDSGSPPLRAEAAFVLHV 462 Query: 248 RDVNDNAPRFYTSLFQ-ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 DVNDNAP F L++ E + E G +VRV A D D+G N ++TY++ +T Sbjct: 463 TDVNDNAPAFDRQLYRPEPLPEVALPGSFVVRVTARDPDQGTNGQVTYSLAPGAHTH--- 519 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 +IDP SG + T+ LD E + + QL+V ATDGG PP +++AT F Sbjct: 520 -WFSIDPTSGIITTAASLDYELEPQPQLIVVATDGGLPPLASSATVSVALQDVNDNEPQF 578 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGG-NTRGRFSITSQNGRGLI 423 Y L E PGT + +TATDAD L Y + G + G G + Sbjct: 579 QRTFYNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLGAGLGSSGSPPFRIDAHSGDV 638 Query: 424 TVAQPLDFKQ-ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 + LD Q + TV+A D GG V++ ++D N+ P F Y AS+ + Sbjct: 639 CTTRTLDRDQGPSSFDFTVTAVDGGGLKSMVYVKVFLSDENDNPPQFYPREYAASISAQS 698 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 P GT VL + A D D G + +++Y + + F ++ Q+G +T L R Sbjct: 699 PPGTAVLRLRAHDPDQGSHGRLSYHI-------LAGNSPPLFTLDEQSGLLTVAWPLARR 751 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 S L + A DGG + V+IS+V P+F+Q Y ++ ED GTSV Sbjct: 752 ANSVVQLEIGAEDGGGLQAEPSARVDISIVPGTPTPPIFEQLQYVFSVPEDVAPGTSVGI 811 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 V A + G + L D G F +D SG+++T + LDRE + V Sbjct: 812 VQAHNPP-GRLAPVTLSLSGGD-PRGLFSLDAVSGLLQTLRPLDRELLGPVLELEVRAGS 869 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 G PP + V + ++D+ND+ P F + T + N+ GT I +RA DPD G N+ V Sbjct: 870 GVPPAFAVARVRVLLDDVNDNSPAFPAPEDTVLLPPNTAPGTPIYTLRALDPDSGVNSRV 929 Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR-AASPPLWNDVRVE 781 +++ G +F+++ G L+ + P + EL R SPP + R+ Sbjct: 930 TFTLLAG-GGGAFTVDPTTG--HVRLMRPLG-PSGGPAHELELEARDGGSPPRTSHFRLR 985 Query: 782 ILVTDV 787 ++V DV Sbjct: 986 VVVQDV 991 Score = 292 bits (716), Expect = 1e-76 Identities = 257/913 (28%), Positives = 420/913 (46%), Gaps = 87/913 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASV-REGASSGTTVL---TLKATDQDIGKNAEVEYTIELVT 66 I V D NDH+P F + R G S T L TL+A D+D G NA + Y + Sbjct: 1948 ITVRDVNDHAPTFPTSPLRLRLPRPGPSFSTPTLALATLRAEDRDAGANASILYRL---- 2003 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 A T P R+ RS L R++V + + ATD P Sbjct: 2004 AGTPPPGTTVDSYTGE-------IRV-ARSPVALG----PRDRV----LFIVATDLGRPA 2047 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 S+T I V + + + P+F + ++ E+ + P+++ +A A G N Sbjct: 2048 R---SATGVIIVGLQGEAERGPRFPRASSEATIREN-APPGTPIVSP-RAVHAG-GTNGP 2101 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSL--VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 I Y+I+ GN + FSI +G +++ + LD+E RLV++A+ GG+ + T L Sbjct: 2102 ITYSILSGNEKGTFSIQPSTGAITVRSAEGLDFEVSPRLRLVLQAESGGAFA---FTVLT 2158 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + ++D NDNAPRF + + E+ P+ +++V+A D D+G +++Y++ Sbjct: 2159 LTLQDANDNAPRFLRPHYVAFLPESRPLEGPLLQVEADDLDQGSGGQISYSLAASQPARG 2218 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 + +DP +G + T+ LDRE A+ +L++ ATD G P +AT Sbjct: 2219 L---FHVDPTTGTITTTAILDREIWAETRLVLMATDRGSPALVGSATLTVMVIDTNDNRP 2275 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLIT 424 +P +E+ ++ED G+ + +T D D L Y ++ + FS+ GR ++ Sbjct: 2276 T-IPQPWELRVSEDALLGSEIAQVTGNDVDSGPVLWYVLSPSGPQDPFSVGRYGGR--VS 2332 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 + PLDF+Q RY L + A D G A + + + D N+ AP F + Y + E P Sbjct: 2333 LTGPLDFEQCDRYQLQLLAHD-GPHEGRANLTVLVEDVNDNAPAFSQSLYQVMLLEHTPP 2391 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT---NKLLDR 541 G+ +L VSATD D G N I+Y L+S F ++P G + T L Sbjct: 2392 GSAILSVSATDRDSGANGHISYHLASPADG---------FSVDPNNGTLFTIVGTVALGH 2442 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 + + + ARD G P + V + + D ND+ P F Y + ED G+++ Sbjct: 2443 DGSGAVDVVLEARDHGAPGRAARATVHVQLQDQNDHAPSFTLSHYRVAVTEDLPPGSTLL 2502 Query: 602 QVGATDAD-------------VGLNGRIHYELDPKDREEG-SFVIDP-ASGVIRTNKALD 646 + ATDAD G GR+ ++L+P+ E G S P A G + + LD Sbjct: 2503 TLEATDADGSRSHAAVDYSIISGNWGRV-FQLEPRLAEAGESAGPGPRALGCLVLLEPLD 2561 Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706 ES+ ++L A D G PPQSS V V + + D+ND+PPVF + E++P+G + Sbjct: 2562 FESLTQYNLTVAAADRGQPPQSSVVPVTVTVLDVNDNPPVFTRASYRVTVPEDTPVGAEL 2621 Query: 707 GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV 766 + A D D GP+ +V +++ GD S F L+ G+ L +D + ++ +++LV Sbjct: 2622 LHVEASDADPGPHGLVRFTVSSGDPSGLFELDESSGT--LRLAHALDCETQA---RHQLV 2676 Query: 767 IRAASP--PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDAD- 822 ++AA P + V I V DVND+ P ++ + + P G + A D D Sbjct: 2677 VQAADPAGAHFALAPVTIEVQDVNDHGPAF-PLNLLSTSVAENQPPGTLVTTLHAIDGDA 2735 Query: 823 -VTDKLQYRILSG----NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIK 877 +L+Y +L LN +TG + + + + V D N + Sbjct: 2736 GAFGRLRYSLLEAGPGPEGREAFALNSSTGELRARVPFDYEHTESFRLLVGAADAGN-LS 2794 Query: 878 AMMQLSVRLITEE 890 A + +SV L+T E Sbjct: 2795 ASVTVSV-LVTGE 2806 Score = 291 bits (713), Expect = 2e-76 Identities = 259/891 (29%), Positives = 401/891 (45%), Gaps = 76/891 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++++L+ N+HSP +V E GT+V + ATD+D G N + Y+++ ++ D+ Sbjct: 1092 RVSILNQNEHSPRLSEDPTFLAVAENQPPGTSVGRVFATDRDSGPNGRLTYSLQQLSEDS 1151 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 FRI ++G + T +LDRE+ + Y +LV+ D SP Sbjct: 1152 ------------------KAFRIHPQTGEVTTLQTLDREQQSSYQLLVQVQDGGSPPR-- 1191 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDN----PVIAKIKATDADVGANS 185 S+T T+HV ++D NDN P F + + I V D ++ ++A D D G N Sbjct: 1192 -STTGTVHVAVLDLNDNSPTFLQASGAAGGGLPIQVPDRVPPGTLVTTLQAKDPDEGENG 1250 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 I Y + G +++ FS+ SG++ L + Y L + A D GSP RS + QLL+ Sbjct: 1251 TILYTLTGPGSEL-FSLHPHSGELLTAAPLIRAERPHYVLTLSAHDQGSPPRSASLQLLV 1309 Query: 246 NIR----------DVNDNAPRFYTSL-FQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294 + D+ + P + + +E + G S++ A GV A LTY Sbjct: 1310 QVLPSARLAEPPPDLAERDPAAPVPVVLTVTAAEGLRPG-SLLGSVAAPEPAGVGA-LTY 1367 Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354 T+ + + +D SG +Y + LD E ++ L +G + Sbjct: 1368 TLVGG---ADPEGTFALDAASGRLYLARPLDFEAGPPWRALTVRAEGPGGAGARLLRVQV 1424 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGR 411 F + L E+ PG + T A+DAD ++ + Y + Sbjct: 1425 QVQDENEHAPAFARDPLALALPENPEPGAALYTFRASDADGPGPNSDVRYRLLRQEPPVP 1484 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATD-----SGGRSDTAMVQINITDANNYA 466 ++ G ++ + LD + +L V ATD S R+ ++ +TD N+ A Sbjct: 1485 -ALRLDARTGALSAPRGLDRETTPALLLLVEATDRPANASRRRAARVSARVFVTDENDNA 1543 Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 PVF + P + ED P G L V A D D+G A+++Y L+S D F + Sbjct: 1544 PVFAS-PSRVRLPEDQPPGPAALHVVARDPDLGEAARVSYRLASG--------GDGHFRL 1594 Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586 + TGA++ + LDRE + ++LTV A D G P S T + +SV DVND P F+QQ Y Sbjct: 1595 HSSTGALSVVRPLDREQRAEHVLTVVASDHGSPPRSATQVLTVSVADVNDEAPTFQQQEY 1654 Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646 + + E+ GTS+ + ATD DVG NG++ Y SF +DP +GV+ T +ALD Sbjct: 1655 SVLLRENNPPGTSLLTLRATDPDVGANGQVTY----GGVSSESFSLDPDTGVLTTLRALD 1710 Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706 RE +L A D G+PPQ + V V + +ED ND P F S L+ + E T+ Sbjct: 1711 REEQEEINLTVYAQDRGSPPQLTHVTVRVAVEDENDHAPTFGSAHLSLEVPEGQD-PQTL 1769 Query: 707 GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPRKKYEL 765 +RA DPD G N + Y I GD S +F L+ G E TM LD E P + + Sbjct: 1770 TMLRASDPDVGANGQLQYRILDGDPSGAFVLDLASG----EFGTMRPLDREVEPAFQLRI 1825 Query: 766 VIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDAD- 822 R P L + + + V D ND+AP +D P G ++ A+D D Sbjct: 1826 EARDGGQPALSATLLLTVTVLDANDHAPAFPVPAYSVEVPED-VPAGTLLLQLQAHDPDA 1884 Query: 823 -VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 + Y L A LL ++G + + L+ T VS DG Sbjct: 1885 GANGHVTY-YLGAGTAGAFLLEPSSGELRTAAALDREQCPSYTFSVSAVDG 1934 Score = 289 bits (709), Expect = 7e-76 Identities = 225/742 (30%), Positives = 345/742 (46%), Gaps = 74/742 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND++P F Y A + E +L ++A D D G ++ Y++ Sbjct: 2159 LTLQDANDNAPRFLRPHYVAFLPESRPLEGPLLQVEADDLDQGSGGQISYSL-------- 2210 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + +F +D +G + T A LDRE A +++ ATD+ SP L Sbjct: 2211 ----------AASQPARGLFHVDPTTGTITTTAILDREIWAETRLVLMATDRGSPA---L 2257 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +AT+ V +ID NDN P + + + V ED + IA++ D D G + Y Sbjct: 2258 VGSATLTVMVIDTNDNRPTIPQP-WELRVSEDALLGSE--IAQVTGNDVDSGP--VLWYV 2312 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + Q FS+ G VSL LD+EQ Y+L + A DG R+N T L + DV Sbjct: 2313 LSPSGPQDPFSVGRYGGRVSLTGPLDFEQCDRYQLQLLAHDGPHEGRANLTVL---VEDV 2369 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDNAP F SL+Q + E+ P G +I+ V A D D G N ++Y + D + Sbjct: 2370 NDNAPAFSQSLYQVMLLEHTPPGSAILSVSATDRDSGANGHISYHLASP-----AD-GFS 2423 Query: 311 IDPRSGWVYT---SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 +DP +G ++T + L + +++ A D G P R+A AT F Sbjct: 2424 VDPNNGTLFTIVGTVALGHDGSGAVDVVLEARDHGAPGRAARATVHVQLQDQNDHAPSFT 2483 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNRLH----YEITGGNTRGRFSITSQ------ 417 Y V + ED PPG+ ++TL ATDAD +R H Y I GN F + + Sbjct: 2484 LSHYRVAVTEDLPPGSTLLTLEATDAD-GSRSHAAVDYSIISGNWGRVFQLEPRLAEAGE 2542 Query: 418 ------NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVF 469 G + + +PLDF+ +Y LTV+A D G +++V + +T D N+ PVF Sbjct: 2543 SAGPGPRALGCLVLLEPLDFESLTQYNLTVAAADRGQPPQSSVVPVTVTVLDVNDNPPVF 2602 Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 A Y +V ED P+G +L V A+D+D G + + +++SS F ++ Sbjct: 2603 TRASYRVTVPEDTPVGAELLHVEASDADPGPHGLVRFTVSS-------GDPSGLFELDES 2655 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589 +G + LD ET + + L V A D + V I V DVND+ P F L + + Sbjct: 2656 SGTLRLAHALDCETQARHQLVVQAADPAGAHFA-LAPVTIEVQDVNDHGPAFPLNLLSTS 2714 Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYEL-----DPKDREEGSFVIDPASGVIRTNKA 644 + E+ GT V+ + A D D G GR+ Y L P+ RE +F ++ ++G +R Sbjct: 2715 VAENQPPGTLVTTLHAIDGDAGAFGRLRYSLLEAGPGPEGRE--AFALNSSTGELRARVP 2772 Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 D E + L A D G S TV V + ED D PVF + F + E + G Sbjct: 2773 FDYEHTESFRLLVGAADAGNLSASVTVSVLVTGEDEYD--PVFLAPAFHFQVPEGARRGH 2830 Query: 705 TIGEIRAHDPDEGPNAVVHYSI 726 ++G ++A D D G + +V YS+ Sbjct: 2831 SLGHVQATDEDGGADGLVLYSL 2852 Score = 284 bits (697), Expect = 2e-74 Identities = 212/695 (30%), Positives = 314/695 (45%), Gaps = 29/695 (4%) Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252 G +ID SG V + LD EQ YR DG T ++ + + D+ND Sbjct: 85 GSGVGTDLAIDEHSGVVRTARVLDREQRDRYRFTAVTPDGA------TVEVTVRVADIND 138 Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312 +AP F + V E+ G A DAD G Y ++ L Sbjct: 139 HAPAFPQARAALQVPEHTAFGTRYPLEPARDADAGRLGTQGYALSGDGAGETFRLETRPG 198 Query: 313 PRSGWV---YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 P V +G+LDRE ++ Y L + A DGG PPR A A F Sbjct: 199 PDGTPVPELVVTGELDRENRSHYMLQLEAYDGGSPPRRAQALLDVTLLDINDHAPAFNQS 258 Query: 370 QYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 +Y ++E PG+PV+ + A+DAD + + YEI + G + GL+ + + Sbjct: 259 RYHAVVSESLAPGSPVLQVFASDADAGVNGAVTYEINRRQSEGDGPFSIDAHTGLLQLER 318 Query: 428 PLDFKQERRYVLTVSATDSGGRSD--TAMVQINITDANNYAP----VFENAPYTASVFED 481 PLDF+Q R + L V A D G + +A V +++ DAN+ P +F +A + V E Sbjct: 319 PLDFEQRRVHELVVQARDGGAHPELGSAFVTVHVRDANDNQPSMTVIFLSADGSPQVSEA 378 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 AP G V +S +D D G A + SL + A++ D + + + LDR Sbjct: 379 APPGQLVARISVSDPDDGDFAHVNVSLEGGEGHFALSTQDSVIYL------VCVARRLDR 432 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN-IMEDALVGTSV 600 E Y L VTA D G P L + V DVNDN P F +QLY + E AL G+ V Sbjct: 433 EERDAYNLRVTATDSGSPPLRAEAAFVLHVTDVNDNAPAFDRQLYRPEPLPEVALPGSFV 492 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 +V A D D G NG++ Y L P F IDP SG+I T +LD E L VA Sbjct: 493 VRVTARDPDQGTNGQVTYSLAPGAHTHW-FSIDPTSGIITTAASLDYELEPQPQLIVVAT 551 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 DGG PP +S+ V + ++D+ND+ P F+ + E + GT ++ A D D GP Sbjct: 552 DGGLPPLASSATVSVALQDVNDNEPQFQRTFYNASLPEGTQPGTCFLQVTATDADSGPFG 611 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVR 779 ++ YS+ G S S S R + ++ T LD + ++ + A L + V Sbjct: 612 LLSYSLGAGLGS-SGSPPFRIDAHSGDVCTTRTLDRDQGPSSFDFTVTAVDGGGLKSMVY 670 Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGNNA 837 V++ ++D NDN P + + P R+ A+D D +L Y IL+GN+ Sbjct: 671 VKVFLSDENDNPPQFYPREYAASISAQSPPGTAVLRLRAHDPDQGSHGRLSYHILAGNSP 730 Query: 838 NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 L L+E +G +T++ L + +E+ DG Sbjct: 731 PLFTLDEQSGLLTVAWPLARRANSVVQLEIGAEDG 765 Score = 281 bits (689), Expect = 2e-73 Identities = 234/800 (29%), Positives = 366/800 (45%), Gaps = 68/800 (8%) Query: 11 INVLDCNDHSPVFEMQQYEAS-VREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++V D ND++P F+ Q Y + E A G+ V+ + A D D G N +V Y++ A T Sbjct: 460 LHVTDVNDNAPAFDRQLYRPEPLPEVALPGSFVVRVTARDPDQGTNGQVTYSLA-PGAHT 518 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 F ID SG + T ASLD E + ++V ATD P Sbjct: 519 ------------------HWFSIDPTSGIITTAASLDYELEPQPQLIVVATDGGLP---P 557 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L+S+AT+ V + D NDN PQF Y S+ E ++ ATDAD G + Y Sbjct: 558 LASSATVSVALQDVNDNEPQFQRTFYNASLPE--GTQPGTCFLQVTATDADSGPFGLLSY 615 Query: 190 AI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQ-VRSYRLVIRAQDGGSPSRSNTTQLLI 245 ++ +G + F ID+ SGDV +TLD +Q S+ + A DGG + + + Sbjct: 616 SLGAGLGSSGSPPFRIDAHSGDVCTTRTLDRDQGPSSFDFTVTAVDGG--GLKSMVYVKV 673 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 + D NDN P+FY + S+S P G +++R++A+D D+G + L+Y + GN Sbjct: 674 FLSDENDNPPQFYPREYAASISAQSPPGTAVLRLRAHDPDQGSHGRLSYHI----LAGNS 729 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 T+D +SG + + L R + QL + A DGG +A Sbjct: 730 PPLFTLDEQSGLLTVAWPLARRANSVVQLEIGAEDGGGLQAEPSARVDISIVPGTPTPPI 789 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTA-TDADEDNRLHYEITGGNTRGRFSITSQNGRGLIT 424 F QY + ED PGT V + A + ++GG+ RG FS+ + + GL+ Sbjct: 790 FEQLQYVFSVPEDVAPGTSVGIVQAHNPPGRLAPVTLSLSGGDPRGLFSLDAVS--GLLQ 847 Query: 425 VAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFED 481 +PLD ++ VL + G A V++ + D N+ +P F T + + Sbjct: 848 TLRPLD-RELLGPVLELEVRAGSGVPPAFAVARVRVLLDDVNDNSPAFPAPEDTVLLPPN 906 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 GT + + A D D G+N+++T++L +A F ++P TG + + L Sbjct: 907 TAPGTPIYTLRALDPDSGVNSRVTFTL--------LAGGGGAFTVDPTTGHVRLMRPLGP 958 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN--EPVFKQQLYTANIMEDALVGTS 599 + L + ARDGG P + + + V DV P F Y ++ GT Sbjct: 959 SGGPAHELELEARDGGSPPRTSHFRLRVVVQDVGTRGLAPRFNSPTYRVDLPSGTTAGTQ 1018 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 V QV A D G I Y L + F ++P SG + ALDRE+ + LK +A Sbjct: 1019 VLQVQAQAPD---GGPITYHL-AAEGASSPFGLEPQSGWLWVRAALDREAQELYILKVMA 1074 Query: 660 IDGGTP---PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 + G Q+ T V + I + N+ P D ++EN P GT++G + A D D Sbjct: 1075 VSGSKAELGQQTGTATVRVSILNQNEHSPRLSEDPTFLAVAENQPPGTSVGRVFATDRDS 1134 Query: 717 GPNAVVHYSIKG-GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR---AASP 772 GPN + YS++ +DS +F + + G E+ T+ LD E + Y+L+++ SP Sbjct: 1135 GPNGRLTYSLQQLSEDSKAFRIHPQTG----EVTTLQTLDREQ-QSSYQLLVQVQDGGSP 1189 Query: 773 PLWNDVRVEILVTDVNDNAP 792 P V + V D+NDN+P Sbjct: 1190 PRSTTGTVHVAVLDLNDNSP 1209 Score = 275 bits (674), Expect = 1e-71 Identities = 226/785 (28%), Positives = 357/785 (45%), Gaps = 45/785 (5%) Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS 164 LDRE+ Y + V ATD SP L + A +++ D NDN P F + Y +++ Sbjct: 430 LDREERDAYNLRVTATDSGSPP---LRAEAAFVLHVTDVNDNAPAFDRQLYRPEPLPEVA 486 Query: 165 VTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR 224 + + V+ ++ A D D G N + Y++ G FSID SG ++ +LDYE + Sbjct: 487 LPGSFVV-RVTARDPDQGTNGQVTYSLAPGAHTHWFSIDPTSGIITTAASLDYELEPQPQ 545 Query: 225 LVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA 284 L++ A DGG P +++ + + ++DVNDN P+F + + S+ E G ++V A DA Sbjct: 546 LIVVATDGGLPPLASSATVSVALQDVNDNEPQFQRTFYNASLPEGTQPGTCFLQVTATDA 605 Query: 285 DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET-QAKYQLLVTATDGGD 343 D G L+Y++ + P ID SG V T+ LDR+ + + VTA DGG Sbjct: 606 DSGPFGLLSYSL-GAGLGSSGSPPFRIDAHSGDVCTTRTLDRDQGPSSFDFTVTAVDGGG 664 Query: 344 PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHY 401 + F P +Y ++ PPGT V+ L A D D+ + RL Y Sbjct: 665 --LKSMVYVKVFLSDENDNPPQFYPREYAASISAQSPPGTAVLRLRAHDPDQGSHGRLSY 722 Query: 402 EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINI 459 I GN+ F++ Q+ GL+TVA PL + L + A D GG +A V I+I Sbjct: 723 HILAGNSPPLFTLDEQS--GLLTVAWPLARRANSVVQLEIGAEDGGGLQAEPSARVDISI 780 Query: 460 TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAH 519 P+FE Y SV ED GT+V +V A + G A +T SLS Sbjct: 781 VPGTPTPPIFEQLQYVFSVPEDVAPGTSVGIVQA-HNPPGRLAPVTLSLSG-------GD 832 Query: 520 HDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNE 578 F ++ +G + T + LDRE + G +L + R G GVP V + + DVNDN Sbjct: 833 PRGLFSLDAVSGLLQTLRPLDRELL-GPVLELEVRAGSGVPPAFAVARVRVLLDDVNDNS 891 Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638 P F T + + GT + + A D D G+N R+ + L G+F +DP +G Sbjct: 892 PAFPAPEDTVLLPPNTAPGTPIYTLRALDPDSGVNSRVTFTL--LAGGGGAFTVDPTTGH 949 Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS--PPVFESDCLTFYI 696 +R + L H+L+ A DGG+PP++S + + ++D+ P F S + Sbjct: 950 VRLMRPLGPSGGPAHELELEARDGGSPPRTSHFRLRVVVQDVGTRGLAPRFNSPTYRVDL 1009 Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756 + GT + +++A PD GP + Y + S+ F LE + G L LD Sbjct: 1010 PSGTTAGTQVLQVQAQAPDGGP---ITYHLAAEGASSPFGLEPQSG----WLWVRAALDR 1062 Query: 757 ESPRKKYELVIRAAS------PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV 810 E+ ++ Y L + A S V + + + N+++P + + ++ P Sbjct: 1063 EA-QELYILKVMAVSGSKAELGQQTGTATVRVSILNQNEHSPRLSEDPTFLAVAENQPPG 1121 Query: 811 GPFGRVPAYDAD--VTDKLQYRILS-GNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867 GRV A D D +L Y + ++ ++ TG +T L+ + V Sbjct: 1122 TSVGRVFATDRDSGPNGRLTYSLQQLSEDSKAFRIHPQTGEVTTLQTLDREQQSSYQLLV 1181 Query: 868 SVTDG 872 V DG Sbjct: 1182 QVQDG 1186 Score = 268 bits (656), Expect = 2e-69 Identities = 244/854 (28%), Positives = 382/854 (44%), Gaps = 66/854 (7%) Query: 18 DHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXX 77 + P F EA++RE A GT +++ +A G N + Y+I L+ + Sbjct: 2063 ERGPRFPRASSEATIRENAPPGTPIVSPRAVHAG-GTNGPITYSI-------LSGNE--- 2111 Query: 78 XXXXXXXXVQDVFRIDGRSGALLTRAS--LDREKVARYTVLVKATDQASPVSDRLSSTAT 135 + F I +GA+ R++ LD E R ++++A S + Sbjct: 2112 ---------KGTFSIQPSTGAITVRSAEGLDFEVSPRLRLVLQAE------SGGAFAFTV 2156 Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195 + + + D NDN P+F Y + E + + P++ +++A D D G+ I Y++ Sbjct: 2157 LTLTLQDANDNAPRFLRPHYVAFLPESRPL-EGPLL-QVEADDLDQGSGGQISYSLAASQ 2214 Query: 196 -TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNA 254 + F +D +G ++ LD E RLV+ A D GSP+ + L + + D NDN Sbjct: 2215 PARGLFHVDPTTGTITTTAILDREIWAETRLVLMATDRGSPALVGSATLTVMVIDTNDNR 2274 Query: 255 PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR 314 P ++ VSE+ +G I +V D D G L Y ++ +G D P ++ Sbjct: 2275 PTI-PQPWELRVSEDALLGSEIAQVTGNDVDSG--PVLWYVLSP---SGPQD-PFSVGRY 2327 Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374 G V +G LD E +YQL + A DG P A F Y+V Sbjct: 2328 GGRVSLTGPLDFEQCDRYQLQLLAHDG---PHEGRANLTVLVEDVNDNAPAFSQSLYQVM 2384 Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434 L E PPG+ +++++ATD D H + FS+ NG L T+ + + Sbjct: 2385 LLEHTPPGSAILSVSATDRDSGANGHISYHLASPADGFSVDPNNGT-LFTIVGTVALGHD 2443 Query: 435 RRYVLTV--SATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 + V A D G GR+ A V + + D N++AP F + Y +V ED P G+T+L Sbjct: 2444 GSGAVDVVLEARDHGAPGRAARATVHVQLQDQNDHAPSFTLSHYRVAVTEDLPPGSTLLT 2503 Query: 491 VSATDSDVG-INAQITYSLSSEISNEA------VAHHDQQFVINPQT-GAITTNKLLDRE 542 + ATD+D +A + YS+ S +A + P+ G + + LD E Sbjct: 2504 LEATDADGSRSHAAVDYSIISGNWGRVFQLEPRLAEAGESAGPGPRALGCLVLLEPLDFE 2563 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 +++ Y LTV A D G P S V ++V+DVNDN PVF + Y + ED VG + Sbjct: 2564 SLTQYNLTVAAADRGQPPQSSVVPVTVTVLDVNDNPPVFTRASYRVTVPEDTPVGAELLH 2623 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 V A+DAD G +G + + + D G F +D +SG +R ALD E+ A H L A D Sbjct: 2624 VEASDADPGPHGLVRFTVSSGD-PSGLFELDESSGTLRLAHALDCETQARHQLVVQAADP 2682 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 + V I+++D+ND P F + L+ ++EN P GT + + A D D G + Sbjct: 2683 AGA-HFALAPVTIEVQDVNDHGPAFPLNLLSTSVAENQPPGTLVTTLHAIDGDAGAFGRL 2741 Query: 723 HYSI----KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDV 778 YS+ G + +F+L + G EL V DYE LV A + L V Sbjct: 2742 RYSLLEAGPGPEGREAFALNSSTG----ELRARVPFDYEHTESFRLLVGAADAGNLSASV 2797 Query: 779 RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD-VTDKLQYRILSGNNA 837 V +LVT ++ PV F + G V A D D D L L+ ++ Sbjct: 2798 TVSVLVTGEDEYDPVFLAPAFHFQVPEGARRGHSLGHVQATDEDGGADGLVLYSLA-TSS 2856 Query: 838 NLILLNETTGSMTL 851 +N+TTG++ L Sbjct: 2857 PYFGINQTTGALYL 2870 Score = 265 bits (650), Expect = 1e-68 Identities = 226/778 (29%), Positives = 342/778 (43%), Gaps = 66/778 (8%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 D ND+ P F+ Y AS+ EG GT L + ATD D G + Y++ + +P Sbjct: 570 DVNDNEPQFQRTFYNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLGAGLGSSGSPP- 628 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREK-VARYTVLVKATDQASPVSDRLSST 133 FRID SG + T +LDR++ + + V A D L S Sbjct: 629 ---------------FRIDAHSGDVCTTRTLDRDQGPSSFDFTVTAVDGGG-----LKSM 668 Query: 134 ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG 193 + V + D+NDN PQF + Y S+ + +++A D D G++ + Y I+ Sbjct: 669 VYVKVFLSDENDNPPQFYPREYAASISAQSP--PGTAVLRLRAHDPDQGSHGRLSYHILA 726 Query: 194 GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDN 253 GN+ F++D SG +++ L +L I A+DGG + ++ I+I Sbjct: 727 GNSPPLFTLDEQSGLLTVAWPLARRANSVVQLEIGAEDGGGLQAEPSARVDISIVPGTPT 786 Query: 254 APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313 P F + SV E+V G S+ VQA++ G A +T +++ D G L D Sbjct: 787 PPIFEQLQYVFSVPEDVAPGTSVGIVQAHNPP-GRLAPVTLSLSGGDPRGLFSL----DA 841 Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373 SG + T LDRE L G PP A A F + V Sbjct: 842 VSGLLQTLRPLDRELLGPVLELEVRAGSGVPPAFAVARVRVLLDDVNDNSPAFPAPEDTV 901 Query: 374 ELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431 L + PGTP+ TL A D D ++R+ + + G G F++ G + + +PL Sbjct: 902 LLPPNTAPGTPIYTLRALDPDSGVNSRVTFTLLAGGG-GAFTVDPTTGH--VRLMRPLGP 958 Query: 432 KQERRYVLTVSATDSGGRSDTAMVQINIT----DANNYAPVFENAPYTASVFEDAPIGTT 487 + L + A D G T+ ++ + AP F + Y + GT Sbjct: 959 SGGPAHELELEARDGGSPPRTSHFRLRVVVQDVGTRGLAPRFNSPTYRVDLPSGTTAGTQ 1018 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 VL V A D G ITY L++E ++ F + PQ+G + LDRE Y Sbjct: 1019 VLQVQAQAPDGG---PITYHLAAEGASSP-------FGLEPQSGWLWVRAALDREAQELY 1068 Query: 548 LLTVTARDGGVPSLSD---TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 +L V A G L T V +S+++ N++ P + + E+ GTSV +V Sbjct: 1069 ILKVMAVSGSKAELGQQTGTATVRVSILNQNEHSPRLSEDPTFLAVAENQPPGTSVGRVF 1128 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 ATD D G NGR+ Y L + +F I P +G + T + LDRE +++ L DGG+ Sbjct: 1129 ATDRDSGPNGRLTYSLQQLSEDSKAFRIHPQTGEVTTLQTLDREQQSSYQLLVQVQDGGS 1188 Query: 665 PPQSSTVIVHIKIEDINDSPPVF------ESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 PP+S+T VH+ + D+ND+ P F L + + P GT + ++A DPDEG Sbjct: 1189 PPRSTTGTVHVAVLDLNDNSPTFLQASGAAGGGLPIQVPDRVPPGTLVTTLQAKDPDEGE 1248 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPP 773 N + Y++ G S FSL G EL+T L + R Y L + A SPP Sbjct: 1249 NGTILYTLT-GPGSELFSLHPHSG----ELLTAAPL-IRAERPHYVLTLSAHDQGSPP 1300 Score = 248 bits (607), Expect = 2e-63 Identities = 244/896 (27%), Positives = 399/896 (44%), Gaps = 78/896 (8%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 ++ ++ + D ND+ P F ++Y AS+ + GT VL L+A D D G + + Y I Sbjct: 669 VYVKVFLSDENDNPPQFYPREYAASISAQSPPGTAVLRLRAHDPDQGSHGRLSYHI---L 725 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 A P +F +D +SG L L R + + + A D Sbjct: 726 AGNSPP----------------LFTLDEQSGLLTVAWPLARRANSVVQLEIGAEDGGGLQ 769 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 ++ +A + ++I+ P F + Y SV ED V + ++A + G + Sbjct: 770 AE---PSARVDISIVPGTPTPPIFEQLQYVFSVPED--VAPGTSVGIVQAHNPP-GRLAP 823 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGGSPSRSNTTQLLI 245 + ++ GG+ + FS+D++SG + ++ LD E + L +RA G P+ + ++ + Sbjct: 824 VTLSLSGGDPRGLFSLDAVSGLLQTLRPLDRELLGPVLELEVRAGSGVPPAFA-VARVRV 882 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 + DVNDN+P F + N G I ++A D D GVN+ +T+T+ G Sbjct: 883 LLDDVNDNSPAFPAPEDTVLLPPNTAPGTPIYTLRALDPDSGVNSRVTFTL----LAGGG 938 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA--TATXXXXXXXXXXXX 363 T+DP +G V L ++L + A DGG PPR++ Sbjct: 939 G-AFTVDPTTGHVRLMRPLGPSGGPAHELELEARDGGSPPRTSHFRLRVVVQDVGTRGLA 997 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423 F Y V+L GT V+ + A A + + Y + F + Q+ G + Sbjct: 998 PRFNSPTYRVDLPSGTTAGTQVLQVQA-QAPDGGPITYHLAAEGASSPFGLEPQS--GWL 1054 Query: 424 TVAQPLDFKQERRYVLTV-----SATDSGGRSDTAMVQINITDANNYAPVFENAPYTASV 478 V LD + + Y+L V S + G ++ TA V+++I + N ++P P +V Sbjct: 1055 WVRAALDREAQELYILKVMAVSGSKAELGQQTGTATVRVSILNQNEHSPRLSEDPTFLAV 1114 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 E+ P GT+V V ATD D G N ++TYSL ++S ++ A F I+PQTG +TT + Sbjct: 1115 AENQPPGTSVGRVFATDRDSGPNGRLTYSL-QQLSEDSKA-----FRIHPQTGEVTTLQT 1168 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA------NIME 592 LDRE S Y L V +DGG P S T V ++V+D+NDN P F Q A + + Sbjct: 1169 LDREQQSSYQLLVQVQDGGSPPRSTTGTVHVAVLDLNDNSPTFLQASGAAGGGLPIQVPD 1228 Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652 GT V+ + A D D G NG I Y L E F + P SG + T L R Sbjct: 1229 RVPPGTLVTTLQAKDPDEGENGTILYTLTGPGSE--LFSLHPHSGELLTAAPLIRAERPH 1286 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKI---EDINDSPP-VFESD-------CLTFYISENSP 701 + L A D G+PP+S+++ + +++ + + PP + E D LT +E Sbjct: 1287 YVLTLSAHDQGSPPRSASLQLLVQVLPSARLAEPPPDLAERDPAAPVPVVLTVTAAEGLR 1346 Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761 G+ +G + A +P G A+ + + G D +F+L+ G L LD+E+ Sbjct: 1347 PGSLLGSVAAPEP-AGVGALTYTLVGGADPEGTFALDAASG----RLYLARPLDFEAGPP 1401 Query: 762 KYELVIRAASPPLWND--VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY 819 L +RA P +RV++ V D N++AP + ++ P A Sbjct: 1402 WRALTVRAEGPGGAGARLLRVQVQVQDENEHAPAFARDPLALALPENPEPGAALYTFRAS 1461 Query: 820 DAD---VTDKLQYRILSGN-NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 DAD ++YR+L + L+ TG+++ L+ + V TD Sbjct: 1462 DADGPGPNSDVRYRLLRQEPPVPALRLDARTGALSAPRGLDRETTPALLLLVEATD 1517 Score = 198 bits (483), Expect = 2e-48 Identities = 154/518 (29%), Positives = 240/518 (46%), Gaps = 23/518 (4%) Query: 369 GQYEVELAEDEPPGTPVVTLTA-TDADEDNRLHYEITGGNTRG-RFSITSQNGRGLITVA 426 G ++++ E++P GT + ++A A L Y I+ G + G++ A Sbjct: 45 GSLDLQIDEEQPAGTLIGDISAGLPAGTAAPLMYFISAQEGSGVGTDLAIDEHSGVVRTA 104 Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 + LD +Q RY T D T V + + D N++AP F A V E GT Sbjct: 105 RVLDREQRDRYRFTAVTPDGA----TVEVTVRVADINDHAPAFPQARAALQVPEHTAFGT 160 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 + A D+D G Y+LS + + E + + LDRE S Sbjct: 161 RYPLEPARDADAGRLGTQGYALSGDGAGETFRLETRPGPDGTPVPELVVTGELDRENRSH 220 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y+L + A DGG P ++++++D+ND+ P F Q Y A + E G+ V QV A+ Sbjct: 221 YMLQLEAYDGGSPPRRAQALLDVTLLDINDHAPAFNQSRYHAVVSESLAPGSPVLQVFAS 280 Query: 607 DADVGLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 DAD G+NG + YE++ + E +G F ID +G+++ + LD E H+L A DGG Sbjct: 281 DADAGVNGAVTYEINRRQSEGDGPFSIDAHTGLLQLERPLDFEQRRVHELVVQARDGGAH 340 Query: 666 PQSSTVIVHIKIEDINDSPP----VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 P+ + V + + D ND+ P +F S + +SE +P G + I DPD+G A Sbjct: 341 PELGSAFVTVHVRDANDNQPSMTVIFLSADGSPQVSEAAPPGQLVARISVSDPDDGDFAH 400 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDV 778 V+ S++GG+ F+L T Q S + LD E R Y L + A SPPL + Sbjct: 401 VNVSLEGGE--GHFALST-QDSVIYLVCVARRLDREE-RDAYNLRVTATDSGSPPLRAEA 456 Query: 779 RVEILVTDVNDNAPVMKDFQIIFNN--YKDCFPVGPFGRVPAYDAD--VTDKLQYRILSG 834 + VTDVNDNAP D Q+ + P RV A D D ++ Y + G Sbjct: 457 AFVLHVTDVNDNAPAF-DRQLYRPEPLPEVALPGSFVVRVTARDPDQGTNGQVTYSLAPG 515 Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 + + ++ T+G +T + L+ + + V TDG Sbjct: 516 AHTHWFSIDPTSGIITTAASLDYELEPQPQLIVVATDG 553 Score = 184 bits (447), Expect = 4e-44 Identities = 162/579 (27%), Positives = 250/579 (43%), Gaps = 45/579 (7%) Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325 + E P G I + A G A L Y ++ ++ +G V + ID SG V T+ LD Sbjct: 51 IDEEQPAGTLIGDISA-GLPAGTAAPLMYFISAQEGSG-VGTDLAIDEHSGVVRTARVLD 108 Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 RE + +Y+ DG AT F + +++ E GT Sbjct: 109 REQRDRYRFTAVTPDG------ATVEVTVRVADINDHAPAFPQARAALQVPEHTAFGTRY 162 Query: 386 VTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRG-----LITVAQPLDFKQERRYV 438 A DAD Y ++G F + ++ G + V LD + Y+ Sbjct: 163 PLEPARDADAGRLGTQGYALSGDGAGETFRLETRPGPDGTPVPELVVTGELDRENRSHYM 222 Query: 439 LTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496 L + A D G R A++ + + D N++AP F + Y A V E G+ VL V A+D+ Sbjct: 223 LQLEAYDGGSPPRRAQALLDVTLLDINDHAPAFNQSRYHAVVSESLAPGSPVLQVFASDA 282 Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556 D G+N +TY + N + D F I+ TG + + LD E + L V ARDG Sbjct: 283 DAGVNGAVTYEI-----NRRQSEGDGPFSIDAHTGLLQLERPLDFEQRRVHELVVQARDG 337 Query: 557 GVPSLSDTTDVEISVVDVNDNEP----VFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612 G + V + V D NDN+P +F + + E A G V+++ +D D G Sbjct: 338 GAHPELGSAFVTVHVRDANDNQPSMTVIFLSADGSPQVSEAAPPGQLVARISVSDPDDGD 397 Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIR---TNKALDRESVATHDLKAVAIDGGTPPQSS 669 ++ L + EG F + VI + LDRE ++L+ A D G+PP + Sbjct: 398 FAHVNVSL---EGGEGHFALSTQDSVIYLVCVARRLDREERDAYNLRVTATDSGSPPLRA 454 Query: 670 TVIVHIKIEDINDSPPVFESDCL-TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 + + D+ND+ P F+ + E + G+ + + A DPD+G N V YS+ Sbjct: 455 EAAFVLHVTDVNDNAPAFDRQLYRPEPLPEVALPGSFVVRVTARDPDQGTNGQVTYSLAP 514 Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR--AASPPLWNDVRVEILVTD 786 G ++ FS++ G + T LDYE + +V+ PPL + V + + D Sbjct: 515 GAHTHWFSIDPTSGI----ITTAASLDYELEPQPQLIVVATDGGLPPLASSATVSVALQD 570 Query: 787 VNDNAPVMKDFQIIFNNY---KDCFPVGPFGRVPAYDAD 822 VNDN P FQ F N + P F +V A DAD Sbjct: 571 VNDNEP---QFQRTFYNASLPEGTQPGTCFLQVTATDAD 606 Score = 146 bits (354), Expect = 8e-33 Identities = 108/389 (27%), Positives = 175/389 (44%), Gaps = 16/389 (4%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGK-NAEVEYTIELV 65 +H Q+ D NDH+P F + Y +V E G+T+LTL+ATD D + +A V+Y+I + Sbjct: 2468 VHVQLQ--DQNDHAPSFTLSHYRVAVTEDLPPGSTLLTLEATDADGSRSHAAVDYSI--I 2523 Query: 66 TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125 + N + G L+ LD E + +Y + V A D+ P Sbjct: 2524 SG---NWGRVFQLEPRLAEAGESAGPGPRALGCLVLLEPLDFESLTQYNLTVAAADRGQP 2580 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 SS + V ++D NDN P F+ +Y V+V ED V + ++A+DAD G + Sbjct: 2581 PQ---SSVVPVTVTVLDVNDNPPVFTRASYRVTVPEDTPV--GAELLHVEASDADPGPHG 2635 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 +R+ + G+ F +D SG + L LD E ++LV++A D + + I Sbjct: 2636 LVRFTVSSGDPSGLFELDESSGTLRLAHALDCETQARHQLVVQAADPAG-AHFALAPVTI 2694 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 ++DVND+ P F +L SV+EN P G + + A D D G L Y++ + Sbjct: 2695 EVQDVNDHGPAFPLNLLSTSVAENQPPGTLVTTLHAIDGDAGAFGRLRYSLLEAGPGPEG 2754 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 ++ +G + D E ++LLV A D G+ SA+ T Sbjct: 2755 REAFALNSSTGELRARVPFDYEHTESFRLLVGAADAGN--LSASVTVSVLVTGEDEYDPV 2812 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDAD 394 F+ + ++ E G + + ATD D Sbjct: 2813 FLAPAFHFQVPEGARRGHSLGHVQATDED 2841 Score = 110 bits (265), Expect = 5e-22 Identities = 99/353 (28%), Positives = 157/353 (44%), Gaps = 39/353 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND+ PVF Y +V E G +L ++A+D D G + V +T+ + D Sbjct: 2590 VTVLDVNDNPPVFTRASYRVTVPEDTPVGAELLHVEASDADPGPHGLVRFTVS--SGDP- 2646 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +F +D SG L +LD E AR+ ++V+A D A Sbjct: 2647 ----------------SGLFELDESSGTLRLAHALDCETQARHQLVVQAADPAGAHF--- 2687 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + A + + + D ND+ P F + SV E+ ++ + A D D GA +RY+ Sbjct: 2688 -ALAPVTIEVQDVNDHGPAFPLNLLSTSVAEN--QPPGTLVTTLHAIDGDAGAFGRLRYS 2744 Query: 191 II----GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 ++ G + F+++S +G++ DYE S+RL++ A D G+ S S T +L+ Sbjct: 2745 LLEAGPGPEGREAFALNSSTGELRARVPFDYEHTESFRLLVGAADAGNLSASVTVSVLVT 2804 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM-TDKDYTG-- 303 D D P F F V E G+S+ VQA D D G + + Y++ T Y G Sbjct: 2805 GEDEYD--PVFLAPAFHFQVPEGARRGHSLGHVQATDEDGGADGLVLYSLATSSPYFGIN 2862 Query: 304 --NVDLPITID---PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 L + +D P SG + G +A +L + G P S +AT Sbjct: 2863 QTTGALYLRVDSRAPGSGTATSGGGGRTRREAPRELRLEVIARGPLPGSRSAT 2915 >UniRef50_Q4SVG4 Cluster: Chromosome 1 SCAF13759, whole genome shotgun sequence; n=7; Tetraodontidae|Rep: Chromosome 1 SCAF13759, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 3762 Score = 313 bits (769), Expect = 4e-83 Identities = 266/904 (29%), Positives = 433/904 (47%), Gaps = 96/904 (10%) Query: 3 VPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 V FC +I + D ND+ P F +Y+ S++ + G+ V+ + A D D G+NA+V YT+ Sbjct: 2510 VAFCT-VRIILTDENDNVPQFAASEYQVSIQSTVNKGSPVVHIMAYDADEGRNADVTYTV 2568 Query: 63 ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122 + E+A +DV I+ +G + + SL + + V+A D Sbjct: 2569 D-------EAEEA----------TEDVIEINPFTGLVTVKDSLVGMENRIFNFKVQARDG 2611 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 + P ++T + V ++ PQFSE YT S +V D PV +I + A Sbjct: 2612 SLPF---YNATVPVQVRVLPPEVPLPQFSEPLYTFS-----AVEDAPVGTEIGSVRA--A 2661 Query: 183 ANSAIRYAIIGGNT-----QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ-DGGSPS 236 +N+ + Y+++ GNT FS+D SG + L K +D+E+ + Y++ + AQ + + Sbjct: 2662 SNTPLIYSLVDGNTLENNKDKVFSLDEDSGTLVLQKPMDHERTKWYQIDVMAQGNHNGTA 2721 Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 ++ + I ++DVNDN P F S ++ ++EN+P G ++++V A DAD N +TY++ Sbjct: 2722 VASLVSISIQVQDVNDNEPLFDASPYRAFLAENMPAGTTVIQVTANDADSETNGLVTYSL 2781 Query: 297 -----TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR-SATA 350 +++ G ++ +ID SGW+ T+ + D E Y+ V ATD G R S++ Sbjct: 2782 EALPEEEEEEAGATEM-FSIDEESGWITTTQEADCEAVRVYRFSVVATDNGGGLRLSSSV 2840 Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRL-HYEITGGN 407 F Y + E+ PG +V++T DAD +NRL IT G+ Sbjct: 2841 LVEVTVTDENDNPPKFSLEAYRGSVVENSSPGEVLVSMTTADADVSLENRLVTCYITDGD 2900 Query: 408 TRGRFSI--TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNY 465 G F+I S+ G GLI + QPLD + + R+ L V ATD G + V +++ D N+ Sbjct: 2901 PLGHFAIIQQSEGGWGLI-LTQPLDREVKDRHALRVMATD-GKFQASVSVDVHVLDINDN 2958 Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525 +P E YT +V E++P VL VSA D DVG N Q++YSL + +F Sbjct: 2959 SPQCEQLVYTEAVMENSPSSRFVLKVSAVDPDVGANGQVSYSLHGP--------NADKFH 3010 Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585 +N +TG + T +LDRE Y L A DGG S +D+ + + D+NDN P F Sbjct: 3011 LNYRTGELLTLAVLDREAEPEYNLVAKATDGG--GRSCQSDILLMIQDMNDNPPRFSSSH 3068 Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645 Y + ++ V T ++ + A D D F +D SG++R + L Sbjct: 3069 YQLTVFDNTTVHTPIAVLYAKDPDTC----------------SFFSLDEFSGLLRLERPL 3112 Query: 646 DRESVATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 ++ T +LK A D G P S V + + ++D PVF S T + E+ +G+ Sbjct: 3113 TPDAPPTFELKVKATDRGLPRHLYSIATVTVAVVSLDDYQPVFLSSEYTAQLPESFAVGS 3172 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKY 763 + + A D G V Y I G++ F L++R G L+T+V LD+E+ R Y Sbjct: 3173 QVLSLSALTRDGGGPDPVAYRIVSGNEDGRFLLDSRTG-----LLTLVAPLDFEASRTYY 3227 Query: 764 ELVI-RAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD 822 V R L + V + VTDVNDNAPV ++ +D P +VPA + Sbjct: 3228 LSVEGRRGKQTLSDITTVMVNVTDVNDNAPVFEEGGYRVEIKEDLPPGSLVMKVPAQEPP 3287 Query: 823 V-------TDK-------LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVS 868 V +D+ L+Y I+SG+ ++ +G ++++ L+ ++ V Sbjct: 3288 VFGGKVTASDQDGPSNSLLRYSIVSGDPLQQFSIHPRSGEISVAAALDREEVPHYSLTVQ 3347 Query: 869 VTDG 872 DG Sbjct: 3348 AADG 3351 Score = 310 bits (762), Expect = 3e-82 Identities = 259/883 (29%), Positives = 400/883 (45%), Gaps = 64/883 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I V D ND++PVF + Y A V EG GT+V+ + A+D D G+N ++ T ++ + Sbjct: 2203 EIEVEDVNDNAPVFSQRAYGAVVAEGLPVGTSVVQVSASDGDSGRNRDL--TFHMLRTER 2260 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 E F ID +G ++T+ LD E ++ + ++ATD + Sbjct: 2261 NETE---------------FFDIDPHTGVIVTKQVLDHEGTNQFHLKIRATDNGTA---P 2302 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LSS A++ VN+ D NDN P F Y ++DE ++ KI+A+D D G + ++Y Sbjct: 2303 LSSEASVLVNVTDVNDNPPDFVSSQYEATLDEKAKC--GHIVIKIQASDPDSGDLNKLQY 2360 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I+ GN F+I+ SG VS Y L + DG T ++ I++ Sbjct: 2361 KILSGNEGRYFNINQSSGIVSFSNVCRRNLEPFYNLTVAVSDG---VFQKTARVNIDMLS 2417 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 N ++P F S+++ ++EN +G ++R+ A D DEG+ + YT+ +K D + Sbjct: 2418 TNKHSPSFKQSVYEAELAENAEVGTQVIRLAAIDPDEGLYGSVDYTIINK----LADEKL 2473 Query: 310 TIDPRSGWVYTSGQLDRETQAK--YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 ID G + T+ LDRE A+ + V A DGG + A T F Sbjct: 2474 AID-SDGQMVTTQPLDRENPAQRIIAVKVMAKDGGG--KVAFCTVRIILTDENDNVPQFA 2530 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITV 425 +Y+V + G+PVV + A DADE + Y + I GL+TV Sbjct: 2531 ASEYQVSIQSTVNKGSPVVHIMAYDADEGRNADVTYTVDEAEEATEDVIEINPFTGLVTV 2590 Query: 426 AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 L + R + V A D + T VQ+ + P F YT S EDAP Sbjct: 2591 KDSLVGMENRIFNFKVQARDGSLPFYNATVPVQVRVLPPEVPLPQFSEPLYTFSAVEDAP 2650 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 +GT + V A N + YSL N + D+ F ++ +G + K +D E Sbjct: 2651 VGTEIGSVRAAS-----NTPLIYSLVD--GNTLENNKDKVFSLDEDSGTLVLQKPMDHER 2703 Query: 544 MSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 Y + V A+ + +++ + I V DVNDNEP+F Y A + E+ GT+V Q Sbjct: 2704 TKWYQIDVMAQGNHNGTAVASLVSISIQVQDVNDNEPLFDASPYRAFLAENMPAGTTVIQ 2763 Query: 603 VGATDADVGLNGRIHYELD--PKDREEGS-----FVIDPASGVIRTNKALDRESVATHDL 655 V A DAD NG + Y L+ P++ EE + F ID SG I T + D E+V + Sbjct: 2764 VTANDADSETNGLVTYSLEALPEEEEEEAGATEMFSIDEESGWITTTQEADCEAVRVYRF 2823 Query: 656 KAVAID-GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 VA D GG SS+V+V + + D ND+PP F + + ENS G + + D Sbjct: 2824 SVVATDNGGGLRLSSSVLVEVTVTDENDNPPKFSLEAYRGSVVENSSPGEVLVSMTTADA 2883 Query: 715 DEG-PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP 773 D N +V I GD F++ +Q L+ LD E + ++ L + A Sbjct: 2884 DVSLENRLVTCYITDGDPLGHFAI-IQQSEGGWGLILTQPLDRE-VKDRHALRVMATDGK 2941 Query: 774 LWNDVRVEILVTDVNDNAPVMKDFQIIFNN-YKDCFPVGPFG-RVPAYDADV--TDKLQY 829 V V++ V D+NDN+P + Q+++ + P F +V A D DV ++ Y Sbjct: 2942 FQASVSVDVHVLDINDNSPQCE--QLVYTEAVMENSPSSRFVLKVSAVDPDVGANGQVSY 2999 Query: 830 RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 L G NA+ LN TG + L+ + TDG Sbjct: 3000 S-LHGPNADKFHLNYRTGELLTLAVLDREAEPEYNLVAKATDG 3041 Score = 285 bits (698), Expect = 2e-74 Identities = 237/799 (29%), Positives = 371/799 (46%), Gaps = 64/799 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NV D ND+ P F QYEA++ E A G V+ ++A+D D G +++Y I L Sbjct: 2311 VNVTDVNDNPPDFVSSQYEATLDEKAKCGHIVIKIQASDPDSGDLNKLQYKI-------L 2363 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + + F I+ SG + R Y + V +D Sbjct: 2364 SGNEGRY------------FNINQSSGIVSFSNVCRRNLEPFYNLTVAVSDGV------F 2405 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 TA ++++++ N + P F + Y + E+ V + ++ A D D G ++ Y Sbjct: 2406 QKTARVNIDMLSTNKHSPSFKQSVYEAELAENAEVGTQ--VIRLAAIDPDEGLYGSVDYT 2463 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDGGSPSRSNTTQLLINIR 248 II + +IDS G + + LD E R + + A+DGG T ++++ Sbjct: 2464 IINKLADEKLAIDS-DGQMVTTQPLDRENPAQRIIAVKVMAKDGGGKVAFCTVRIILT-- 2520 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D NDN P+F S +Q S+ V G +V + AYDADEG NA++TYT+ D+ D+ Sbjct: 2521 DENDNVPQFAASEYQVSIQSTVNKGSPVVHIMAYDADEGRNADVTYTV-DEAEEATEDV- 2578 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 I I+P +G V L + V A DG P +AT F Sbjct: 2579 IEINPFTGLVTVKDSLVGMENRIFNFKVQARDGSLPFYNATVPVQVRVLPPEVPLPQFSE 2638 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT--RGRFSITS-QNGRGLITV 425 Y ED P GT + ++ A + L Y + GNT + + S G + + Sbjct: 2639 PLYTFSAVEDAPVGTEIGSVRAA---SNTPLIYSLVDGNTLENNKDKVFSLDEDSGTLVL 2695 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAM-----VQINITDANNYAPVFENAPYTASVFE 480 +P+D ++ + Y + V A G + TA+ + I + D N+ P+F+ +PY A + E Sbjct: 2696 QKPMDHERTKWYQIDVMA--QGNHNGTAVASLVSISIQVQDVNDNEPLFDASPYRAFLAE 2753 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSS-EISNEAVAHHDQQFVINPQTGAITTNKLL 539 + P GTTV+ V+A D+D N +TYSL + E A + F I+ ++G ITT + Sbjct: 2754 NMPAGTTVIQVTANDADSETNGLVTYSLEALPEEEEEEAGATEMFSIDEESGWITTTQEA 2813 Query: 540 DRETMSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 D E + Y +V A D GG LS + VE++V D NDN P F + Y +++E++ G Sbjct: 2814 DCEAVRVYRFSVVATDNGGGLRLSSSVLVEVTVTDENDNPPKFSLEAYRGSVVENSSPGE 2873 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS----GVIRTNKALDRESVATHD 654 + + DADV L R+ G F I S G+I T + LDRE H Sbjct: 2874 VLVSMTTADADVSLENRLVTCYITDGDPLGHFAIIQQSEGGWGLILT-QPLDREVKDRHA 2932 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 L+ +A DG ++V V + + DIND+ P E T + ENSP + ++ A DP Sbjct: 2933 LRVMATDG---KFQASVSVDVHVLDINDNSPQCEQLVYTEAVMENSPSSRFVLKVSAVDP 2989 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL 774 D G N V YS+ G +++ F L R G EL+T+ LD E+ +Y LV +A Sbjct: 2990 DVGANGQVSYSLH-GPNADKFHLNYRTG----ELLTLAVLDREA-EPEYNLVAKATDGGG 3043 Query: 775 WN-DVRVEILVTDVNDNAP 792 + + +++ D+NDN P Sbjct: 3044 RSCQSDILLMIQDMNDNPP 3062 Score = 283 bits (694), Expect = 5e-74 Identities = 196/598 (32%), Positives = 291/598 (48%), Gaps = 32/598 (5%) Query: 156 TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTL 215 +V + ED + N + +++ATDAD G S + YAI GN FSID+ +GD+ LV +L Sbjct: 679 SVELSEDFPL--NSSVVRLRATDADSGFGSLLVYAISAGNQDGCFSIDTFAGDLRLVCSL 736 Query: 216 DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275 D E+ Y L I D G P ++ + + + DVNDN P F + V EN + Sbjct: 737 DRERNAFYVLNITVYDLGMPQKTAWRFVAVTVTDVNDNPPEFDQLRYVTRVPENAEVDSV 796 Query: 276 IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL 335 + A D D V L +++ +IDP +G V LDRET ++ L Sbjct: 797 VFTAHAADPDLDVGGRLRFSLLTPTNA------FSIDPVTGEVTLKAPLDRETTPRHDLQ 850 Query: 336 VTATDGGD--PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393 + A DG + P + F+P Y++++ ED P GT ++ + + D Sbjct: 851 IVAKDGAERGPRLVSVVDLVVVLQDVNDNPPRFLPHNYKIKVPEDLPVGTLLLWVESVDL 910 Query: 394 D--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG---G 448 D + Y + G F + S G +T+ + LDF++ R Y LTV A D G Sbjct: 911 DLASGGLVTYNLKNPE-GGSFRLDSST--GALTLERELDFERRRSYTLTVRAVDHGLPRS 967 Query: 449 RSDTAMVQINITDANN--YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506 S + V+I + D N + P+F Y A+V EDA +GT+VL ++A+D DVG + + + Sbjct: 968 LSSSCFVEIEVLDVNENLHRPLFSEFVYEAAVMEDAAVGTSVLKLTASDKDVGRDGEFRF 1027 Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566 + + S V F I+ +TG I + K+LDRE M Y L+V D G L T Sbjct: 1028 HI-QDGSGLGV------FSIDEETGVICSAKILDREKMPHYWLSVLVGDLGTEPLLSWTH 1080 Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE 626 V + V+DVNDN P Q +Y A++ E+ SV+QV ATDAD G++ + + R Sbjct: 1081 VFLRVLDVNDNAPQLSQPVYFASVQENVDGVGSVAQVWATDADASSEGKLSFHMLESHRT 1140 Query: 627 EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686 F +DP +GV+ T ALDRE H ++ V D G+P SST V I++ D ND+ P Sbjct: 1141 H--FDVDPKTGVVSTLSALDREEKEEHSVEVVVSDNGSPSLSSTTTVVIRVLDDNDNQPK 1198 Query: 687 FESDCLTFYISE--NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 F I E S + + A D D G NA V Y ++ D S F ++ G Sbjct: 1199 FTDKLFHIKIPEQRRSAGEQEVYRMVARDDDRGSNAAVTYRLQ-DDHSERFKIDPLLG 1255 Score = 283 bits (693), Expect = 6e-74 Identities = 230/748 (30%), Positives = 351/748 (46%), Gaps = 69/748 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+ P+F+ Y A + E +GTTV+ + A D D N V Y++E + + Sbjct: 2730 IQVQDVNDNEPLFDASPYRAFLAENMPAGTTVIQVTANDADSETNGLVTYSLEALPEE-- 2787 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 E+A ++F ID SG + T D E V Y V ATD + RL Sbjct: 2788 EEEEAGAT---------EMFSIDEESGWITTTQEADCEAVRVYRFSVVATDNGGGL--RL 2836 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG-ANSAIRY 189 SS+ + V + D+NDN P+FS + Y SV E+ S V+ + DADV N + Sbjct: 2837 SSSVLVEVTVTDENDNPPKFSLEAYRGSVVENSS--PGEVLVSMTTADADVSLENRLVTC 2894 Query: 190 AIIGGNTQMQFSIDSLS-GDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 I G+ F+I S G L+ T LD E + L + A DG + + + ++ Sbjct: 2895 YITDGDPLGHFAIIQQSEGGWGLILTQPLDREVKDRHALRVMATDGKFQA---SVSVDVH 2951 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + D+NDN+P+ ++ E+V EN P +++V A D D G N +++Y++ + N D Sbjct: 2952 VLDINDNSPQCEQLVYTEAVMENSPSSRFVLKVSAVDPDVGANGQVSYSL----HGPNAD 3007 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 ++ R+G + T LDRE + +Y L+ ATDGG RS + F Sbjct: 3008 -KFHLNYRTGELLTLAVLDREAEPEYNLVAKATDGGG--RSCQSDILLMIQDMNDNPPRF 3064 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 Y++ + ++ TP+ L A D D T FS+ + GL+ + Sbjct: 3065 SSSHYQLTVFDNTTVHTPIAVLYAKDPD-------------TCSFFSLDEFS--GLLRLE 3109 Query: 427 QPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 +PL + L V ATD G A V + + ++Y PVF ++ YTA + E Sbjct: 3110 RPLTPDAPPTFELKVKATDRGLPRHLYSIATVTVAVVSLDDYQPVFLSSEYTAQLPESFA 3169 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 +G+ VL +SA D G + Y + S NE D +F+++ +TG +T LD E Sbjct: 3170 VGSQVLSLSALTRDGGGPDPVAYRIVS--GNE-----DGRFLLDSRTGLLTLVAPLDFEA 3222 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV--- 600 Y L+V R G +LSD T V ++V DVNDN PVF++ Y I ED G+ V Sbjct: 3223 SRTYYLSVEGR-RGKQTLSDITTVMVNVTDVNDNAPVFEEGGYRVEIKEDLPPGSLVMKV 3281 Query: 601 ---------SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA 651 +V A+D D N + Y + D + F I P SG I ALDRE V Sbjct: 3282 PAQEPPVFGGKVTASDQDGPSNSLLRYSIVSGDPLQ-QFSIHPRSGEISVAAALDREEVP 3340 Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711 + L A DGG PP SS ++V I + D+ND+PP+F + + E P+G+++ ++ Sbjct: 3341 HYSLTVQAADGGDPPLSSAILVTITVADVNDNPPIFSRVNHSLLLQEGEPVGSSVLQLVV 3400 Query: 712 HDPDEGPNA-VVHYSIKGGDDSNSFSLE 738 D D N + I G+ F ++ Sbjct: 3401 TDRDTPRNGPPFSFHIVSGNQERRFHVD 3428 Score = 278 bits (681), Expect = 2e-72 Identities = 231/774 (29%), Positives = 365/774 (47%), Gaps = 61/774 (7%) Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDE--DIS--VT---DNPVIAKIKATDADVGA 183 SS+ + + + D+NDN P F +K Y + E DI VT P++ I+A+DAD A Sbjct: 1683 SSSTFVSIYVTDENDNAPVFRQKEYLGQISEAADIGAMVTGEGSRPLV--IQASDADRDA 1740 Query: 184 NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR--SNTT 241 N+ + Y I+ FSID G +SL+ +D+E YR ++ +D G P R + Sbjct: 1741 NALLVYQILEPELLSVFSIDPSMGTISLLSAVDFEARAEYRFSVQVRDSGEPCRYAAEPA 1800 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 ++ + + D+ND AP F + +++ SV G + V A DAD V Y++ + Sbjct: 1801 KVTVRVLDLNDCAPHFTSPVYESSVILPAVRGMEVTHVTARDADSAV----AYSIVE--- 1853 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 GN+ +++P SG + S YQL++ A+DG AT Sbjct: 1854 -GNLHGAFSVEPSSGLITVSNATG--FTGFYQLVLRASDG---LHQDLATVRVNGSALTG 1907 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421 F Y V +AE+ + L A + L + + N G+FSI++ +G Sbjct: 1908 GHLGFEQDVYTVSVAENLRTVRTLAALKARGCLFNEPLVFSLL--NPEGKFSISASSG-V 1964 Query: 422 LITVAQPLDFKQERRY--VLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479 L T P D ++ Y V+ V T + R+ A V++ I D N+ P F N P++ + Sbjct: 1965 LETTGIPFDREETDVYEVVVMVRDTRTPPRTARAQVRVFIDDVNDSPPQFSNLPFSIVIP 2024 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E + G + SA D D+G NA I YSL + S F I+P G I+ + L Sbjct: 2025 ESSEPGDVLYQASAVDGDLGENASILYSLEEDYS---------LFRIDPHAGDISLQRPL 2075 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 D E ++ Y+LTV A D G PS S T + + V N + PVF+ LY + E+ T+ Sbjct: 2076 DFEALNKYVLTVLAVDEGEPSHSATAQLSLQV--RNQSSPVFQTLLYPLKVPENIPPFTT 2133 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 + V A + D R+ Y L ++ + F ID +GV+ LD ES H L A Sbjct: 2134 ILHVQARNPD---GYRLVYNLQEENASK-HFHIDFKTGVLTVTDPLDYESQRAHVLTVRA 2189 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 D T S V I++ED+ND+ PVF ++E P+GT++ ++ A D D G N Sbjct: 2190 SDSVT-GVFSEASVEIEVEDVNDNAPVFSQRAYGAVVAEGLPVGTSVVQVSASDGDSGRN 2248 Query: 720 --AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPL 774 H +++ F ++ G +VT LD+E ++ L IRA + PL Sbjct: 2249 RDLTFHMLRTERNETEFFDIDPHTG----VIVTKQVLDHEG-TNQFHLKIRATDNGTAPL 2303 Query: 775 WNDVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYR 830 ++ V + VTDVNDN P V ++ + C + ++ A D D D KLQY+ Sbjct: 2304 SSEASVLVNVTDVNDNPPDFVSSQYEATLDEKAKCGHI--VIKIQASDPDSGDLNKLQYK 2361 Query: 831 ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884 ILSGN +N+++G ++ S N+ + V+V+DGV + A + + + Sbjct: 2362 ILSGNEGRYFNINQSSGIVSFSNVCRRNLEPFYNLTVAVSDGVFQKTARVNIDM 2415 Score = 273 bits (670), Expect = 4e-71 Identities = 247/880 (28%), Positives = 388/880 (44%), Gaps = 73/880 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTV-------LTLKATDQDIGKNAEVEYTIE 63 I V D ND++PVF ++Y + E A G V L ++A+D D NA + Y I Sbjct: 1690 IYVTDENDNAPVFRQKEYLGQISEAADIGAMVTGEGSRPLVIQASDADRDANALLVYQI- 1748 Query: 64 LVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQA 123 L PE + VF ID G + +++D E A Y V+ D Sbjct: 1749 ------LEPE------------LLSVFSIDPSMGTISLLSAVDFEARAEYRFSVQVRDSG 1790 Query: 124 SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183 P + A + V ++D ND P F+ Y SV + + + A DAD Sbjct: 1791 EPCR-YAAEPAKVTVRVLDLNDCAPHFTSPVYESSVI--LPAVRGMEVTHVTARDAD--- 1844 Query: 184 NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 SA+ Y+I+ GN FS++ SG +++ + Y+LV+RA DG + + Sbjct: 1845 -SAVAYSIVEGNLHGAFSVEPSSGLITVSNATGFTGF--YQLVLRASDG---LHQDLATV 1898 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 +N + F ++ SV+EN+ ++ ++A N L +++ Sbjct: 1899 RVNGSALTGGHLGFEQDVYTVSVAENLRTVRTLAALKARGCL--FNEPLVFSLL------ 1950 Query: 304 NVDLPITIDPRSGWVYTSG-QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 N + +I SG + T+G DRE Y+++V D PPR+A A Sbjct: 1951 NPEGKFSISASSGVLETTGIPFDREETDVYEVVVMVRDTRTPPRTARAQVRVFIDDVNDS 2010 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422 F + + + E PG + +A D D + F I G Sbjct: 2011 PPQFSNLPFSIVIPESSEPGDVLYQASAVDGDLGENASILYSLEEDYSLFRIDPHAGD-- 2068 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 I++ +PLDF+ +YVLTV A D G S +A Q+++ N +PVF+ Y V E+ Sbjct: 2069 ISLQRPLDFEALNKYVLTVLAVDEGEPSHSATAQLSLQVRNQSSPVFQTLLYPLKVPENI 2128 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 P TT+L V A + D ++ Y+L E +++ F I+ +TG +T LD E Sbjct: 2129 PPFTTILHVQARNPD---GYRLVYNLQEENASK-------HFHIDFKTGVLTVTDPLDYE 2178 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 + ++LTV A D V + VEI V DVNDN PVF Q+ Y A + E VGTSV Q Sbjct: 2179 SQRAHVLTVRASDS-VTGVFSEASVEIEVEDVNDNAPVFSQRAYGAVVAEGLPVGTSVVQ 2237 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFV-IDPASGVIRTNKALDRESVATHDLKAVAID 661 V A+D D G N + + + +R E F IDP +GVI T + LD E LK A D Sbjct: 2238 VSASDGDSGRNRDLTFHMLRTERNETEFFDIDPHTGVIVTKQVLDHEGTNQFHLKIRATD 2297 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 GT P SS V + + D+ND+PP F S + E + G + +I+A DPD G Sbjct: 2298 NGTAPLSSEASVLVNVTDVNDNPPDFVSSQYEATLDEKAKCGHIVIKIQASDPDSGDLNK 2357 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781 + Y I G++ F++ G +V+ ++ + Y L + + RV Sbjct: 2358 LQYKILSGNEGRYFNINQSSG-----IVSFSNVCRRNLEPFYNLTVAVSDGVFQKTARVN 2412 Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILSGNNAN 838 I + N ++P K + + VG R+ A D D + + Y I++ A+ Sbjct: 2413 IDMLSTNKHSPSFKQ-SVYEAELAENAEVGTQVIRLAAIDPDEGLYGSVDYTIIN-KLAD 2470 Query: 839 LILLNETTGSMTLSPQLNTNVP--KLATMEVSVTDGVNEI 876 L ++ G M + L+ P ++ ++V DG ++ Sbjct: 2471 EKLAIDSDGQMVTTQPLDRENPAQRIIAVKVMAKDGGGKV 2510 Score = 260 bits (637), Expect = 4e-67 Identities = 247/897 (27%), Positives = 390/897 (43%), Gaps = 81/897 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I++L N HSP F+ YEA + E A GT V+ L A D D G V+YTI AD Sbjct: 2413 IDMLSTNKHSPSFKQSVYEAELAENAEVGTQVIRLAAIDPDEGLYGSVDYTIINKLAD-- 2470 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + ID G ++T LDRE A+ + VK A ++ Sbjct: 2471 -----------------EKLAIDS-DGQMVTTQPLDRENPAQRIIAVKV--MAKDGGGKV 2510 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + T+ + + D+NDN PQF+ Y VS+ ++ +PV+ I A DAD G N+ + Y Sbjct: 2511 AF-CTVRIILTDENDNVPQFAASEYQVSIQSTVN-KGSPVV-HIMAYDADEGRNADVTYT 2567 Query: 191 IIGGN--TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 + T+ I+ +G V++ +L + R + ++A+DG P + T + + + Sbjct: 2568 VDEAEEATEDVIEINPFTGLVTVKDSLVGMENRIFNFKVQARDGSLPFYNATVPVQVRVL 2627 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD-YTGNVDL 307 P+F L+ S E+ P+G I V+A N L Y++ D + N D Sbjct: 2628 PPEVPLPQFSEPLYTFSAVEDAPVGTEIGSVRAAS-----NTPLIYSLVDGNTLENNKDK 2682 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX-XF 366 ++D SG + +D E YQ+ V A + A+ F Sbjct: 2683 VFSLDEDSGTLVLQKPMDHERTKWYQIDVMAQGNHNGTAVASLVSISIQVQDVNDNEPLF 2742 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDAD-EDNRL----------HYEITGGNTRGRFSIT 415 Y LAE+ P GT V+ +TA DAD E N L E G T FSI Sbjct: 2743 DASPYRAFLAENMPAGTTVIQVTANDADSETNGLVTYSLEALPEEEEEEAGATE-MFSID 2801 Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR---SDTAMVQINITDANNYAPVFENA 472 ++G IT Q D + R Y +V ATD+GG S + +V++ +TD N+ P F Sbjct: 2802 EESG--WITTTQEADCEAVRVYRFSVVATDNGGGLRLSSSVLVEVTVTDENDNPPKFSLE 2859 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 Y SV E++ G ++ ++ D+DV + ++ ++ + + H G Sbjct: 2860 AYRGSVVENSSPGEVLVSMTTADADVSLENRLVTCYITD--GDPLGHFAIIQQSEGGWGL 2917 Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592 I T L DRE + L V A DG + V++ V+D+NDN P +Q +YT +ME Sbjct: 2918 ILTQPL-DREVKDRHALRVMATDG---KFQASVSVDVHVLDINDNSPQCEQLVYTEAVME 2973 Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652 ++ V +V A D DVG NG++ Y L + ++ F ++ +G + T LDRE+ Sbjct: 2974 NSPSSRFVLKVSAVDPDVGANGQVSYSLHGPNADK--FHLNYRTGELLTLAVLDREAEPE 3031 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 ++L A A DGG S ++ + I+D+ND+PP F S + +N+ + T I + A Sbjct: 3032 YNLVAKATDGGGRSCQSDIL--LMIQDMNDNPPRFSSSHYQLTVFDNTTVHTPIAVLYAK 3089 Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP 772 DPD + FSL+ G + E D + K + R Sbjct: 3090 DPDT---------------CSFFSLDEFSGLLRLERPLTPDAP-PTFELKVKATDRGLPR 3133 Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG---RVPAYDADVTDKLQY 829 L++ V + V ++D PV + + F VG D D + Y Sbjct: 3134 HLYSIATVTVAVVSLDDYQPVFLSSEYTAQ-LPESFAVGSQVLSLSALTRDGGGPDPVAY 3192 Query: 830 RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886 RI+SGN LL+ TG +TL L+ + + V G + + + V + Sbjct: 3193 RIVSGNEDGRFLLDSRTGLLTLVAPLDFEASRTYYLSVEGRRGKQTLSDITTVMVNV 3249 Score = 260 bits (637), Expect = 4e-67 Identities = 205/664 (30%), Positives = 317/664 (47%), Gaps = 60/664 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ V D ND+ P F ++ Y SV E +S G ++++ D D+ + T + D Sbjct: 2843 EVTVTDENDNPPKFSLEAYRGSVVENSSPGEVLVSMTTADADVSLENRL-VTCYITDGDP 2901 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L +Q + +G G +LT+ LDRE R+ + V ATD + Sbjct: 2902 LG----------HFAIIQ---QSEGGWGLILTQP-LDREVKDRHALRVMATD------GK 2941 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 ++ ++ V+++D NDN PQ + YT +V E+ + + K+ A D DVGAN + Y Sbjct: 2942 FQASVSVDVHVLDINDNSPQCEQLVYTEAVMENSP--SSRFVLKVSAVDPDVGANGQVSY 2999 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 ++ G N +F ++ +G++ + LD E Y LV +A DGG RS + +L+ I+D Sbjct: 3000 SLHGPNAD-KFHLNYRTGELLTLAVLDREAEPEYNLVAKATDGGG--RSCQSDILLMIQD 3056 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 +NDN PRF +S +Q +V +N + I + A D D T + Sbjct: 3057 MNDNPPRFSSSHYQLTVFDNTTVHTPIAVLYAKDPD-------TCSF------------F 3097 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRS-ATATXXXXXXXXXXXXXXFMP 368 ++D SG + L + ++L V ATD G P + AT F+ Sbjct: 3098 SLDEFSGLLRLERPLTPDAPPTFELKVKATDRGLPRHLYSIATVTVAVVSLDDYQPVFLS 3157 Query: 369 GQYEVELAEDEPPGTPVVTLTAT--DADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 +Y +L E G+ V++L+A D + + Y I GN GRF + S+ G L+T+ Sbjct: 3158 SEYTAQLPESFAVGSQVLSLSALTRDGGGPDPVAYRIVSGNEDGRFLLDSRTG--LLTLV 3215 Query: 427 QPLDFKQERRYVLTVSATDSGGR-SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 PLDF+ R Y L+V SD V +N+TD N+ APVFE Y + ED P G Sbjct: 3216 APLDFEASRTYYLSVEGRRGKQTLSDITTVMVNVTDVNDNAPVFEEGGYRVEIKEDLPPG 3275 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNE----AVAHHD--QQFVINPQTGAITTNKLL 539 + V+ V A + V ++T S SN ++ D QQF I+P++G I+ L Sbjct: 3276 SLVMKVPAQEPPV-FGGKVTASDQDGPSNSLLRYSIVSGDPLQQFSIHPRSGEISVAAAL 3334 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 DRE + Y LTV A DGG P LS V I+V DVNDN P+F + ++ + E VG+S Sbjct: 3335 DREEVPHYSLTVQAADGGDPPLSSAILVTITVADVNDNPPIFSRVNHSLLLQEGEPVGSS 3394 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 V Q+ TD D NG +E F +D G++ + L ++ H LK + Sbjct: 3395 VLQLVVTDRDTPRNGPPFSFHIVSGNQERRFHVD-QGGLLSLSAPLRKKVKGHHQLK-IQ 3452 Query: 660 IDGG 663 + GG Sbjct: 3453 VTGG 3456 Score = 240 bits (587), Expect = 5e-61 Identities = 229/818 (27%), Positives = 366/818 (44%), Gaps = 78/818 (9%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 VF +D SG L+ + +D E+ Y + V A Q + ++S +I + + D NDN P Sbjct: 2683 VFSLDEDSGTLVLQKPMDHERTKWYQIDVMA--QGNHNGTAVASLVSISIQVQDVNDNEP 2740 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG---------GNTQMQ 199 F Y + E++ + ++ A DAD N + Y++ G T+M Sbjct: 2741 LFDASPYRAFLAENMPA--GTTVIQVTANDADSETNGLVTYSLEALPEEEEEEAGATEM- 2797 Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIRDVNDNAPRFY 258 FSID SG ++ + D E VR YR + A D G R +++ L+ + + D NDN P+F Sbjct: 2798 FSIDEESGWITTTQEADCEAVRVYRFSVVATDNGGGLRLSSSVLVEVTVTDENDNPPKFS 2857 Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGV-NAELTYTMTDKDYTGNVDLPITIDPRSGW 317 ++ SV EN G +V + DAD + N +T +TD D G+ I GW Sbjct: 2858 LEAYRGSVVENSSPGEVLVSMTTADADVSLENRLVTCYITDGDPLGH--FAIIQQSEGGW 2915 Query: 318 -VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376 + + LDRE + ++ L V ATDG A+ + Y + Sbjct: 2916 GLILTQPLDREVKDRHALRVMATDG---KFQASVSVDVHVLDINDNSPQCEQLVYTEAVM 2972 Query: 377 EDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434 E+ P V+ ++A D D + ++ Y + G N +F + + G L+T+A LD + E Sbjct: 2973 ENSPSSRFVLKVSAVDPDVGANGQVSYSLHGPNA-DKFHLNYRTGE-LLTLAV-LDREAE 3029 Query: 435 RRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494 Y L ATD GGRS + + + I D N+ P F ++ Y +VF++ + T + V+ A Sbjct: 3030 PEYNLVAKATDGGGRSCQSDILLMIQDMNDNPPRFSSSHYQLTVFDNTTVHTPIAVLYAK 3089 Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554 D D T S F ++ +G + + L + + L V A Sbjct: 3090 DPD-------TCSF---------------FSLDEFSGLLRLERPLTPDAPPTFELKVKAT 3127 Query: 555 DGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613 D G+P L V ++VV ++D +PVF YTA + E VG+ V + A D G Sbjct: 3128 DRGLPRHLYSIATVTVAVVSLDDYQPVFLSSEYTAQLPESFAVGSQVLSLSALTRDGGGP 3187 Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673 + Y + E+G F++D +G++ LD E+ T+ L +V G S V Sbjct: 3188 DPVAYRI-VSGNEDGRFLLDSRTGLLTLVAPLDFEASRTYYL-SVEGRRGKQTLSDITTV 3245 Query: 674 HIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP-----------DEGP-NAV 721 + + D+ND+ PVFE I E+ P G+ + ++ A +P +GP N++ Sbjct: 3246 MVNVTDVNDNAPVFEEGGYRVEIKEDLPPGSLVMKVPAQEPPVFGGKVTASDQDGPSNSL 3305 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDV 778 + YSI GD FS+ R G E+ LD E Y L ++AA PPL + + Sbjct: 3306 LRYSIVSGDPLQQFSIHPRSG----EISVAAALDREEV-PHYSLTVQAADGGDPPLSSAI 3360 Query: 779 RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVT---DKLQYRILSG 834 V I V DVNDN P+ ++ PVG ++ D D + I+SG Sbjct: 3361 LVTITVADVNDNPPIFSRVNHSL-LLQEGEPVGSSVLQLVVTDRDTPRNGPPFSFHIVSG 3419 Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 N +++ G ++LS L V +++ VT G Sbjct: 3420 NQERRFHVDQ-GGLLSLSAPLRKKVKGHHQLKIQVTGG 3456 Score = 238 bits (583), Expect = 1e-60 Identities = 208/709 (29%), Positives = 319/709 (44%), Gaps = 62/709 (8%) Query: 17 NDHSPVFE-MQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDA 75 N HSP F+ + + E ++V+ L+ATD D G + + Y I D Sbjct: 666 NRHSPKFDPVLPSSVELSEDFPLNSSVVRLRATDADSGFGSLLVYAISAGNQD------- 718 Query: 76 XXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTAT 135 F ID +G L SLDRE+ A Y + + D P + ++ Sbjct: 719 ------------GCFSIDTFAGDLRLVCSLDRERNAFYVLNITVYDLGMP---QKTAWRF 763 Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195 + V + D NDN P+F + Y V E+ V + V+ A D D+ +R++++ Sbjct: 764 VAVTVTDVNDNPPEFDQLRYVTRVPENAEV--DSVVFTAHAADPDLDVGGRLRFSLL--T 819 Query: 196 TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG--SPSRSNTTQLLINIRDVNDN 253 FSID ++G+V+L LD E + L I A+DG P + L++ ++DVNDN Sbjct: 820 PTNAFSIDPVTGEVTLKAPLDRETTPRHDLQIVAKDGAERGPRLVSVVDLVVVLQDVNDN 879 Query: 254 APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313 PRF ++ V E++P+G ++ V++ D D +TY + K+ G +D Sbjct: 880 PPRFLPHNYKIKVPEDLPVGTLLLWVESVDLDLASGGLVTYNL--KNPEGG---SFRLDS 934 Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP----G 369 +G + +LD E + Y L V A D G PRS +++ P Sbjct: 935 STGALTLERELDFERRRSYTLTVRAVDHG-LPRSLSSSCFVEIEVLDVNENLHRPLFSEF 993 Query: 370 QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 YE + ED GT V+ LTA+D D D + I G+ G FSI + G+I A+ Sbjct: 994 VYEAAVMEDAAVGTSVLKLTASDKDVGRDGEFRFHIQDGSGLGVFSIDEET--GVICSAK 1051 Query: 428 PLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 LD ++ Y L+V D G V + + D N+ AP Y ASV E+ Sbjct: 1052 ILDREKMPHYWLSVLVGDLGTEPLLSWTHVFLRVLDVNDNAPQLSQPVYFASVQENVDGV 1111 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 +V V ATD+D ++++ + + H F ++P+TG ++T LDRE Sbjct: 1112 GSVAQVWATDADASSEGKLSFHM--------LESHRTHFDVDPKTGVVSTLSALDREEKE 1163 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED--ALVGTSVSQV 603 + + V D G PSLS TT V I V+D NDN+P F +L+ I E + V ++ Sbjct: 1164 EHSVEVVVSDNGSPSLSSTTTVVIRVLDDNDNQPKFTDKLFHIKIPEQRRSAGEQEVYRM 1223 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 A D D G N + Y L +D F IDP GV+ + + +KA D G Sbjct: 1224 VARDDDRGSNAAVTYRL--QDDHSERFKIDPLLGVVTARGDFWPGNYSILTVKAT--DQG 1279 Query: 664 TPPQSSTV---IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 +PP+SST + I + +D P FE TF + E P+ +G I Sbjct: 1280 SPPRSSTARLDVEWIALPPPSDEPISFEEPHFTFAVMETEPVTHMVGII 1328 Score = 206 bits (503), Expect = 7e-51 Identities = 171/563 (30%), Positives = 261/563 (46%), Gaps = 34/563 (6%) Query: 246 NIRDVNDNAPRFYTSLFQE-SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 ++ N ++P+F L +SE+ P+ S+VR++A DAD G + L Y ++ GN Sbjct: 661 DVHVTNRHSPKFDPVLPSSVELSEDFPLNSSVVRLRATDADSGFGSLLVYAIS----AGN 716 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 D +ID +G + LDRE A Y L +T D G P ++A Sbjct: 717 QDGCFSIDTFAGDLRLVCSLDRERNAFYVLNITVYDLGMPQKTAWRFVAVTVTDVNDNPP 776 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGL 422 F +Y + E+ + V T A D D D RL + + FSI G Sbjct: 777 EFDQLRYVTRVPENAEVDSVVFTAHAADPDLDVGGRLRFSLL--TPTNAFSIDPVTGE-- 832 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT----DANNYAPVFENAPYTASV 478 +T+ PLD + R+ L + A D R + +++ D N+ P F Y V Sbjct: 833 VTLKAPLDRETTPRHDLQIVAKDGAERGPRLVSVVDLVVVLQDVNDNPPRFLPHNYKIKV 892 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 ED P+GT +L V + D D+ +TY+L + F ++ TGA+T + Sbjct: 893 PEDLPVGTLLLWVESVDLDLASGGLVTYNLKNPEGGS--------FRLDSSTGALTLERE 944 Query: 539 LDRETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDN--EPVFKQQLYTANIMEDAL 595 LD E Y LTV A D G+P SLS + VEI V+DVN+N P+F + +Y A +MEDA Sbjct: 945 LDFERRRSYTLTVRAVDHGLPRSLSSSCFVEIEVLDVNENLHRPLFSEFVYEAAVMEDAA 1004 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655 VGTSV ++ A+D DVG +G + + G F ID +GVI + K LDRE + + L Sbjct: 1005 VGTSVLKLTASDKDVGRDGEFRFHIQDGSGL-GVFSIDEETGVICSAKILDREKMPHYWL 1063 Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 + D GT P S V +++ D+ND+ P + EN ++ ++ A D D Sbjct: 1064 SVLVGDLGTEPLLSWTHVFLRVLDVNDNAPQLSQPVYFASVQENVDGVGSVAQVWATDAD 1123 Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIRA-ASPP 773 + + + ++ F ++ + G + T+ LD E + E+V+ SP Sbjct: 1124 ASSEGKLSFHMLESHRTH-FDVDPKTGV----VSTLSALDREEKEEHSVEVVVSDNGSPS 1178 Query: 774 LWNDVRVEILVTDVNDNAPVMKD 796 L + V I V D NDN P D Sbjct: 1179 LSSTTTVVIRVLDDNDNQPKFTD 1201 Score = 197 bits (480), Expect = 4e-48 Identities = 239/910 (26%), Positives = 402/910 (44%), Gaps = 101/910 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND P+F Y S+ E A ++V+T+ ATD D+G NA+ Y+ Sbjct: 104 VRVLDANDLKPLFYPASYSVSIAEDAELRSSVVTVSATDADVGSNADFYYSF----TSRA 159 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS--D 128 +P F +D +G + L+ + RY + V A D+ +S Sbjct: 160 HP-----------------FAVDPFTGTVSLVRKLNHTRSQRYELTVLAEDRTKKISGVQ 202 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 + + A I V++ + P S+ + V V D VT V +++A VG+ S + Sbjct: 203 KFGNVAKITVHVQKTSKASPVISQVSKPV-VSADGKVT---VDVQVEAGVKPVGSLSVVG 258 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGGSPSRSNTTQLLINI 247 + G T + V K +D+ Q S + L ++A+D PS S++ Q ++I Sbjct: 259 GDLCGCFTVIPSGAQGDRFQVISTKRIDWPQAPSGFNLSLQARDTSFPSLSSSVQQ-VHI 317 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 + F S ++ ++SE P ++ V + E NA ++++ D D G Sbjct: 318 AAAQISPLAFKESTYRVTLSEFSPPNTHVLLVSL--SSEAHNA--SFSIKD-DPDG---A 369 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 P I+P +G + T+ +LD E++ +YQ V A +GG+ A A F Sbjct: 370 PFRINPLTGVIVTTQKLDYESKRRYQFDVAA-NGGE----AEARVVIEVKDENDNSPQFA 424 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 YE L E+ P G+ V+ ++ATDAD N+ G T G+I+ + Sbjct: 425 SPSYEASLDENAPVGSSVLQVSATDADGGKNAFVTYALANS-GPSPFTIHPFTGVISTSG 483 Query: 428 PLDFK-QERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 LD++ RRY L V A+DSG R V I + + N+ P+ E ++ DAP Sbjct: 484 HLDYELMRRRYHLRVWASDSGSPFSRVSECPVTITLNNVNDNIPLLERVGCNTTLPVDAP 543 Query: 484 IGTTVLVVSATDSDV----------GINAQI--TYSLSSEIS-NEAVAHHDQQFVINPQT 530 +G TV+ +SA D D G Q+ S+S IS A+ + F ++ Sbjct: 544 VGGTVVQLSAIDPDELQQLRYLIQSGNELQVFAVDSVSGVISLKRAIPPSEGSFTLSVAA 603 Query: 531 --GAITTNKLLDRETMS--GYLLTVTARDGGV-------------PSLSDTTDVEISVVD 573 G + + R T++ G TV ++ G+ P L+ D V Sbjct: 604 TDGRHQSEAAVVRVTVTHRGEEATVACQETGISKQLTARLIQSMEPFLAQEEDEAFPDVH 663 Query: 574 V-NDNEPVFKQQLYTA-NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631 V N + P F L ++ + ED + +SV ++ ATDAD G + Y + + ++G F Sbjct: 664 VTNRHSPKFDPVLPSSVELSEDFPLNSSVVRLRATDADSGFGSLLVYAISAGN-QDGCFS 722 Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691 ID +G +R +LDRE A + L D G P +++ V + + D+ND+PP F+ Sbjct: 723 IDTFAGDLRLVCSLDRERNAFYVLNITVYDLGMPQKTAWRFVAVTVTDVNDNPPEFDQLR 782 Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751 + EN+ + + + A DPD + +S+ +N+FS++ G E+ Sbjct: 783 YVTRVPENAEVDSVVFTAHAADPDLDVGGRLRFSLL--TPTNAFSIDPVTG----EVTLK 836 Query: 752 VDLDYE-SPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYK-- 805 LD E +PR ++V + + P L + V + +++ DVNDN P + + +NYK Sbjct: 837 APLDRETTPRHDLQIVAKDGAERGPRLVSVVDLVVVLQDVNDNPP-----RFLPHNYKIK 891 Query: 806 --DCFPVGPFGR-VPAYDADV-TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPK 861 + PVG V + D D+ + L L L+ +TG++TL +L+ + Sbjct: 892 VPEDLPVGTLLLWVESVDLDLASGGLVTYNLKNPEGGSFRLDSSTGALTLERELDFERRR 951 Query: 862 LATMEVSVTD 871 T+ V D Sbjct: 952 SYTLTVRAVD 961 Score = 195 bits (475), Expect = 2e-47 Identities = 156/531 (29%), Positives = 255/531 (48%), Gaps = 32/531 (6%) Query: 373 VELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 VEL+ED P + VV L ATDAD + L Y I+ GN G FSI + G + + LD Sbjct: 680 VELSEDFPLNSSVVRLRATDADSGFGSLLVYAISAGNQDGCFSIDTFAGD--LRLVCSLD 737 Query: 431 FKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 ++ YVL ++ D G TA V + +TD N+ P F+ Y V E+A + + V Sbjct: 738 RERNAFYVLNITVYDLGMPQKTAWRFVAVTVTDVNDNPPEFDQLRYVTRVPENAEVDSVV 797 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 A D D+ + ++ +SL + + F I+P TG +T LDRET + Sbjct: 798 FTAHAADPDLDVGGRLRFSLLTPTN---------AFSIDPVTGEVTLKAPLDRETTPRHD 848 Query: 549 LTVTARDGGV--PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 L + A+DG P L D+ + + DVNDN P F Y + ED VGT + V + Sbjct: 849 LQIVAKDGAERGPRLVSVVDLVVVLQDVNDNPPRFLPHNYKIKVPEDLPVGTLLLWVESV 908 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D D+ G + Y L K+ E GSF +D ++G + + LD E ++ L A+D G P Sbjct: 909 DLDLASGGLVTYNL--KNPEGGSFRLDSSTGALTLERELDFERRRSYTLTVRAVDHGLPR 966 Query: 667 Q-SSTVIVHIKIEDINDS--PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 SS+ V I++ D+N++ P+F + E++ +GT++ ++ A D D G + Sbjct: 967 SLSSSCFVEIEVLDVNENLHRPLFSEFVYEAAVMEDAAVGTSVLKLTASDKDVGRDGEFR 1026 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY--ELVIRAASPPLWNDVRVE 781 + I+ G FS++ G + + LD E + LV + PL + V Sbjct: 1027 FHIQDGSGLGVFSIDEETGV----ICSAKILDREKMPHYWLSVLVGDLGTEPLLSWTHVF 1082 Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGNNANL 839 + V DVNDNAP + + ++ VG +V A DAD + KL + +L + + Sbjct: 1083 LRVLDVNDNAPQLSQPVYFASVQENVDGVGSVAQVWATDADASSEGKLSFHMLESHRTHF 1142 Query: 840 ILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITE 889 ++ TG ++ L+ + ++EV V+D G + + + +R++ + Sbjct: 1143 D-VDPKTGVVSTLSALDREEKEEHSVEVVVSDNGSPSLSSTTTVVIRVLDD 1192 Score = 190 bits (463), Expect = 5e-46 Identities = 188/663 (28%), Positives = 308/663 (46%), Gaps = 54/663 (8%) Query: 23 FEMQQYEASVREGASSGTTVLTLKATDQDIG-KNAEVEYTIELVTADTLNPEDAXXXXXX 81 F YEAS++E + T V T T + + E++Y++ D L +A Sbjct: 1 FTQPVYEASIKENSPPRTYVETPAKTGIQLSLPHWELDYSVVSGDDDDLFQAEALKVGDF 60 Query: 82 XXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNII 141 R+ RSG A L+RE YT+ V+AT+++S L + + V ++ Sbjct: 61 CF------LRVRTRSG---NAALLNREVRDAYTLTVEATEKSSD----LRAKTKVLVRVL 107 Query: 142 DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFS 201 D ND P F +Y+VS+ ED + + + + ATDADVG+N+ Y+ + F+ Sbjct: 108 DANDLKPLFYPASYSVSIAEDAELRSS--VVTVSATDADVGSNADFYYSFT--SRAHPFA 163 Query: 202 IDSLSGDVSLVKTLDYEQVRSYRLVIRAQD-----GGSPSRSNTTQLLINIRDVNDNAPR 256 +D +G VSLV+ L++ + + Y L + A+D G N ++ ++++ + +P Sbjct: 164 VDPFTGTVSLVRKLNHTRSQRYELTVLAEDRTKKISGVQKFGNVAKITVHVQKTSKASP- 222 Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD-LPITIDPRS 315 + + + VS + G V VQ + GV + ++ D G +P Sbjct: 223 VISQVSKPVVSAD---GKVTVDVQV---EAGVKPVGSLSVVGGDLCGCFTVIPSGAQGDR 276 Query: 316 GWVYTSGQLD-RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374 V ++ ++D + + + L + A D P S++ F Y V Sbjct: 277 FQVISTKRIDWPQAPSGFNLSLQARDTSFPSLSSSVQQVHIAAAQISPLA-FKESTYRVT 335 Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434 L+E PP T V+ ++ + E + + I F I G +I Q LD++ + Sbjct: 336 LSEFSPPNTHVLLVSLSS--EAHNASFSIKDDPDGAPFRINPLTG--VIVTTQKLDYESK 391 Query: 435 RRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494 RRY V+A +GG ++ A V I + D N+ +P F + Y AS+ E+AP+G++VL VSAT Sbjct: 392 RRYQFDVAA--NGGEAE-ARVVIEVKDENDNSPQFASPSYEASLDENAPVGSSVLQVSAT 448 Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM-SGYLLTVTA 553 D+D G NA +TY+L++ F I+P TG I+T+ LD E M Y L V A Sbjct: 449 DADGGKNAFVTYALANS--------GPSPFTIHPFTGVISTSGHLDYELMRRRYHLRVWA 500 Query: 554 RDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612 D G P S V I++ +VNDN P+ ++ + DA VG +V Q+ A D D Sbjct: 501 SDSGSPFSRVSECPVTITLNNVNDNIPLLERVGCNTTLPVDAPVGGTVVQLSAIDPDE-- 558 Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672 ++ Y L E F +D SGVI +A+ S + L A DG +++ V Sbjct: 559 LQQLRY-LIQSGNELQVFAVDSVSGVISLKRAIP-PSEGSFTLSVAATDGRHQSEAAVVR 616 Query: 673 VHI 675 V + Sbjct: 617 VTV 619 Score = 170 bits (414), Expect = 4e-40 Identities = 153/543 (28%), Positives = 248/543 (45%), Gaps = 47/543 (8%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 D ND+ P F Y+ V E GT +L +++ D D+ V Y ++ NPE Sbjct: 875 DVNDNPPRFLPHNYKIKVPEDLPVGTLLLWVESVDLDLASGGLVTYNLK-------NPEG 927 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134 FR+D +GAL LD E+ YT+ V+A D P S LSS+ Sbjct: 928 GS-------------FRLDSSTGALTLERELDFERRRSYTLTVRAVDHGLPRS--LSSSC 972 Query: 135 TIHVNIIDDNDNY--PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192 + + ++D N+N P FSE Y +V ED +V + + K+ A+D DVG + R+ I Sbjct: 973 FVEIEVLDVNENLHRPLFSEFVYEAAVMEDAAVGTS--VLKLTASDKDVGRDGEFRFHIQ 1030 Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252 G+ FSID +G + K LD E++ Y L + D G+ + T + + + DVND Sbjct: 1031 DGSGLGVFSIDEETGVICSAKILDREKMPHYWLSVLVGDLGTEPLLSWTHVFLRVLDVND 1090 Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312 NAP+ ++ SV ENV S+ +V A DAD +L++ M + T +D Sbjct: 1091 NAPQLSQPVYFASVQENVDGVGSVAQVWATDADASSEGKLSFHMLESHRT-----HFDVD 1145 Query: 313 PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE 372 P++G V T LDRE + ++ + V +D G P S+T T F + Sbjct: 1146 PKTGVVSTLSALDREEKEEHSVEVVVSDNGSPSLSSTTTVVIRVLDDNDNQPKFTDKLFH 1205 Query: 373 VELAEDEPPG--TPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQP 428 +++ E V + A D D + + Y + ++ RF I G++T Sbjct: 1206 IKIPEQRRSAGEQEVYRMVARDDDRGSNAAVTYRLQDDHSE-RFKIDPL--LGVVTARG- 1261 Query: 429 LDFKQERRYVLTVSATDSGG--RSDTAMVQIN---ITDANNYAPVFENAPYTASVFEDAP 483 DF +LTV ATD G RS TA + + + ++ FE +T +V E P Sbjct: 1262 -DFWPGNYSILTVKATDQGSPPRSSTARLDVEWIALPPPSDEPISFEEPHFTFAVMETEP 1320 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 + T ++ + T++ + IT + S +++ A A + + G ++T+ LL+ + Sbjct: 1321 V-THMVGIIMTETYGQMWYSITAATSLQVALLASAPPAPPPLSSGLLGLLSTH-LLEEDP 1378 Query: 544 MSG 546 SG Sbjct: 1379 HSG 1381 Score = 160 bits (389), Expect = 4e-37 Identities = 121/408 (29%), Positives = 199/408 (48%), Gaps = 29/408 (7%) Query: 451 DTAMVQINITDANNYAPVFENA-PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509 D A +++T N ++P F+ P + + ED P+ ++V+ + ATD+D G + + Y++S Sbjct: 656 DEAFPDVHVT--NRHSPKFDPVLPSSVELSEDFPLNSSVVRLRATDADSGFGSLLVYAIS 713 Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569 + + D F I+ G + LDRE + Y+L +T D G+P + V + Sbjct: 714 A-------GNQDGCFSIDTFAGDLRLVCSLDRERNAFYVLNITVYDLGMPQKTAWRFVAV 766 Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629 +V DVNDN P F Q Y + E+A V + V A D D+ + GR+ + L + Sbjct: 767 TVTDVNDNPPEFDQLRYVTRVPENAEVDSVVFTAHAADPDLDVGGRLRFSL---LTPTNA 823 Query: 630 FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT--PPQSSTVIVHIKIEDINDSPPVF 687 F IDP +G + LDRE+ HDL+ VA DG P S V + + ++D+ND+PP F Sbjct: 824 FSIDPVTGEVTLKAPLDRETTPRHDLQIVAKDGAERGPRLVSVVDLVVVLQDVNDNPPRF 883 Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747 + E+ P+GT + + + D D +V Y++K + SF L++ G+ Sbjct: 884 LPHNYKIKVPEDLPVGTLLLWVESVDLDLASGGLVTYNLK-NPEGGSFRLDSSTGA---- 938 Query: 748 LVTMVDLDYESPRKKYELVIRAASPPLWNDVR----VEILVTDVNDN--APVMKDFQIIF 801 L +LD+E R+ Y L +RA L + VEI V DVN+N P+ +F Sbjct: 939 LTLERELDFER-RRSYTLTVRAVDHGLPRSLSSSCFVEIEVLDVNENLHRPLFSEFVYEA 997 Query: 802 NNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTG 847 +D ++ A D DV + ++ I G+ + ++E TG Sbjct: 998 AVMEDAAVGTSVLKLTASDKDVGRDGEFRFHIQDGSGLGVFSIDEETG 1045 Score = 140 bits (339), Expect = 5e-31 Identities = 146/566 (25%), Positives = 251/566 (44%), Gaps = 39/566 (6%) Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383 L+RE + Y L V AT+ R+ T F P Y V +AED + Sbjct: 75 LNREVRDAYTLTVEATEKSSDLRAKTKVLVRVLDANDLKPL-FYPASYSVSIAEDAELRS 133 Query: 384 PVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443 VVT++ATDAD + + + + F++ G +++ + L+ + +RY LTV A Sbjct: 134 SVVTVSATDADVGSNADFYYSFTSRAHPFAVDPFTGT--VSLVRKLNHTRSQRYELTVLA 191 Query: 444 TD-----SGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496 D SG + + A + +++ + +PV V D + T + V A Sbjct: 192 EDRTKKISGVQKFGNVAKITVHVQKTSKASPVISQVSKPV-VSADGKV-TVDVQVEAGVK 249 Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556 VG + + L + +F + I+T ++ + SG+ L++ ARD Sbjct: 250 PVGSLSVVGGDLCGCFTVIPSGAQGDRFQV------ISTKRIDWPQAPSGFNLSLQARDT 303 Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616 PSLS + ++ + + FK+ Y + E + T V V + N Sbjct: 304 SFPSLSSSVQ-QVHIAAAQISPLAFKESTYRVTLSEFSPPNTHVLLVSLSSE--AHNASF 360 Query: 617 HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676 + DP + F I+P +GVI T + LD ES + VA +GG + V++ +K Sbjct: 361 SIKDDP---DGAPFRINPLTGVIVTTQKLDYESKRRYQFD-VAANGGEA--EARVVIEVK 414 Query: 677 IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736 D ND+ P F S + EN+P+G+++ ++ A D D G NA V Y++ S F+ Sbjct: 415 --DENDNSPQFASPSYEASLDENAPVGSSVLQVSATDADGGKNAFVTYALANSGPS-PFT 471 Query: 737 LETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SP-PLWNDVRVEILVTDVNDNAP 792 + G + T LDYE R++Y L + A+ SP ++ V I + +VNDN P Sbjct: 472 IHPFTG----VISTSGHLDYELMRRRYHLRVWASDSGSPFSRVSECPVTITLNNVNDNIP 527 Query: 793 VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLS 852 +++ D G ++ A D D +L+Y I SGN + ++ +G ++L Sbjct: 528 LLERVGCNTTLPVDAPVGGTVVQLSAIDPDELQQLRYLIQSGNELQVFAVDSVSGVISLK 587 Query: 853 PQLNTNVPKLATMEVSVTDGVNEIKA 878 + + T+ V+ TDG ++ +A Sbjct: 588 RAIPPSEGSF-TLSVAATDGRHQSEA 612 Score = 109 bits (263), Expect = 8e-22 Identities = 115/461 (24%), Positives = 195/461 (42%), Gaps = 38/461 (8%) Query: 439 LTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV-------LVV 491 L VSA+ GG S + V I +TD N+ APVF Y + E A IG V LV+ Sbjct: 1672 LEVSASTVGGASSSTFVSIYVTDENDNAPVFRQKEYLGQISEAADIGAMVTGEGSRPLVI 1731 Query: 492 SATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTV 551 A+D+D NA + Y + + E ++ F I+P G I+ +D E + Y +V Sbjct: 1732 QASDADRDANALLVYQI---LEPELLS----VFSIDPSMGTISLLSAVDFEARAEYRFSV 1784 Query: 552 TARDGGVPS--LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 RD G P ++ V + V+D+ND P F +Y ++++ A+ G V+ V A DAD Sbjct: 1785 QVRDSGEPCRYAAEPAKVTVRVLDLNDCAPHFTSPVYESSVILPAVRGMEVTHVTARDAD 1844 Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669 + Y + + G+F ++P+SG+I + A + L A DG Sbjct: 1845 ----SAVAYSI-VEGNLHGAFSVEPSSGLITVSNATG--FTGFYQLVLRASDG---LHQD 1894 Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729 V + + FE D T ++EN T+ ++A N + +S+ Sbjct: 1895 LATVRVNGSALTGGHLGFEQDVYTVSVAENLRTVRTLAALKARGCLF--NEPLVFSLL-- 1950 Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR---AASPPLWNDVRVEILVTD 786 + FS+ G + T + D E YE+V+ +PP +V + + D Sbjct: 1951 NPEGKFSISASSGVLE---TTGIPFDREE-TDVYEVVVMVRDTRTPPRTARAQVRVFIDD 2006 Query: 787 VNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETT 846 VND+ P + + P + A D D+ + + +L ++ Sbjct: 2007 VNDSPPQFSNLPFSIVIPESSEPGDVLYQASAVDGDLGENASILYSLEEDYSLFRIDPHA 2066 Query: 847 GSMTLSPQLNTN-VPKLATMEVSVTDGVNEIKAMMQLSVRL 886 G ++L L+ + K ++V +G A QLS+++ Sbjct: 2067 GDISLQRPLDFEALNKYVLTVLAVDEGEPSHSATAQLSLQV 2107 Score = 38.3 bits (85), Expect = 3.0 Identities = 47/199 (23%), Positives = 91/199 (45%), Gaps = 18/199 (9%) Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGL-NGRIHYEL---DPKD--REEGSFVIDP 634 F Q +Y A+I E++ T V T + L + + Y + D D + E V D Sbjct: 1 FTQPVYEASIKENSPPRTYVETPAKTGIQLSLPHWELDYSVVSGDDDDLFQAEALKVGDF 60 Query: 635 ASGVIRTNKA----LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690 +RT L+RE + L A + + ++ T ++ +++ D ND P+F Sbjct: 61 CFLRVRTRSGNAALLNREVRDAYTLTVEATEKSSDLRAKTKVL-VRVLDANDLKPLFYPA 119 Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750 + I+E++ + +++ + A D D G NA +YS ++ F+++ G+ V+ Sbjct: 120 SYSVSIAEDAELRSSVVTVSATDADVGSNADFYYSFT--SRAHPFAVDPFTGT-----VS 172 Query: 751 MVDLDYESPRKKYELVIRA 769 +V + ++YEL + A Sbjct: 173 LVRKLNHTRSQRYELTVLA 191 >UniRef50_UPI000155CE87 Cluster: PREDICTED: similar to FAT tumor suppressor homolog 4 (Drosophila); n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to FAT tumor suppressor homolog 4 (Drosophila) - Ornithorhynchus anatinus Length = 1683 Score = 311 bits (764), Expect = 2e-82 Identities = 305/1104 (27%), Positives = 476/1104 (43%), Gaps = 103/1104 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQ-DIGKNAEVEYTIELVTADT 69 ++V+D NDH P F Y V + S GT V+ + A D D G N+ VEY L+T Sbjct: 573 VHVVDGNDHPPRFLSAGYSTPVPKDVSVGTRVIQVAAADDGDFGLNSRVEY---LLTGQ- 628 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 E A F +D +G + A L + + + V A D P Sbjct: 629 ---EPAAR------------FGLDAETGWVSVAAPLTGDVDRTFRLSVTARDGGRPP--- 670 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISV--------------TDNPV----- 170 LS+ AT+ + + + N + P+F V V E ++V +N + Sbjct: 671 LSAGATVRILVTEANAHTPEFPRDRVRVEVPETLAVGAVVCVLAARDSDPAENGLLFYAF 730 Query: 171 -----IAKIKATDA-DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR 224 ++ + A D +V S + Y + G +F +D+ +G VS+ L + R++R Sbjct: 731 PPGTGVSYLAAEDEQEVSIKSRVEYLLTGQEPAARFGLDAETGWVSVAAPLTGDVDRTFR 790 Query: 225 LVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA 284 L + A+DGG P S + I + + N + P F + V E + +G + + A DA Sbjct: 791 LSVTARDGGRPPLSAGATVRILVTEANAHTPEFPRDRVRVEVPETLAVGAVVCVLAARDA 850 Query: 285 DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP 344 D N L Y ++ GN + ++ +G + +G LD ET +++ V+ATDGG Sbjct: 851 DPAENGLLAYAVS----AGNGEGLFAVNASTGVLTLAGALDYETGRSHEVTVSATDGGWA 906 Query: 345 PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT 404 R+ F +Y E+AE+ P GTPVVTL ATDAD Sbjct: 907 ARTGFCAVTVDVLDVNDNPPVFAGAEYTPEVAENAPSGTPVVTLRATDADSGPNAVVAYA 966 Query: 405 GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA--TDSGGRSDTAMVQINITDA 462 G N G+++ LD++ R + LTV A R A V + +T Sbjct: 967 LHEADGDLFAVDPN-TGVVSTQGFLDYETRREHRLTVKAFNVPDEERCAFAAVTVRVTGV 1025 Query: 463 NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522 N Y P F +A Y V E AP GT V V A D D G + +++Y L E + Sbjct: 1026 NEYIPRFVSAAYGFEVSEAAPPGTPVGQVFAGDRDRGPDGEVSYLLFGESRRKG------ 1079 Query: 523 QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD--VEISVVDVNDNEPV 580 F + +TG I+ LDRE L V A++ G +D + V ++V+D ND PV Sbjct: 1080 -FRVERETGQISVAGPLDREREGTVALRVLAKNAGPIRGADVDEVAVNVTVLDAND-PPV 1137 Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVI 639 F + Y I E GT V+ VGA DAD V R Y + P + +F + P +G + Sbjct: 1138 FGAETYRVRISEGVPPGTHVTFVGAADADSVPAWSRFSYRVGPAGGD--AFSVHPQTGQV 1195 Query: 640 RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699 LDRE++ ++L +A+D GTPP + ++ + +ED+ND+ PV ++EN Sbjct: 1196 TVTAPLDRETLPVYNLTVLAVDTGTPPATGRAVLLVTLEDVNDNGPVLTVG--EARVAEN 1253 Query: 700 SPIGTTIGEIRAHDPDEGPN--AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757 P GT + +RA DPD PN + GG ++ F L S L T ++D E Sbjct: 1254 QPPGTVVTTLRASDPDLPPNQGPFTFRLLGGGPAADYFGL-----SPAGLLTTAREIDRE 1308 Query: 758 S-PRKKYELVIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR 815 R +V+R + PP+ + V ILV D NDN + ++ ++Y FP G G Sbjct: 1309 QVSRFLLPVVVRDSGLPPMSSTGTVLILVADRNDNPSQPRPLEVFVHHYGGPFPGGVLGG 1368 Query: 816 VPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVN- 874 V D D D + + SG L + G+ +LS + + V DG + Sbjct: 1369 VRPLDPDEDDDFRCSLASGPAG---LFSVPAGTCSLSARARA-ADGTFDLRVLGDDGAHG 1424 Query: 875 EIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLS----PLLGFFIDGLAAIIPCPKEN 930 + + +++S L +SI +RL +A FL+ PLL L+ + Sbjct: 1425 PVVSDVRVSFAAFGNATLDHSILLRLAAPSAGAFLAAHYLPLLQIAGSQLSGL----GGG 1480 Query: 931 IYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLA 990 + ++ + +D + G L ++ R P + G + S ++E V+ R + R+ Sbjct: 1481 LQLYGLYEDEEGGGAFL-LAAVRRGPHRYLSPGGAAAFFES---VKESVF--RQSGLRIE 1534 Query: 991 TVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGF 1050 V+ P C PC N C L G S V+ + F CQC G+ Sbjct: 1535 EVEPDP-----CARGPCRNGGACARRLAVGPLFKSRESPPVILVANEVLQPFVCQCAPGY 1589 Query: 1051 TGVNCETILTKASCEVDGDGSICR 1074 G CET + + +G CR Sbjct: 1590 AGGRCETDVDECLPAPCHNGGACR 1613 Score = 305 bits (748), Expect = 1e-80 Identities = 265/903 (29%), Positives = 406/903 (44%), Gaps = 92/903 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NVLD NDHSP F Q + ASV E A G TV +D+D G+NA Y+I AD+ Sbjct: 365 VNVLDENDHSPRFS-QLFSASVPENAPVGFTVTRATTSDEDEGQNAVSRYSI----ADSG 419 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P F ID +G + LDRE VARY + V A D VS Sbjct: 420 LP-----------------FAIDPSTGDITVSRPLDREDVARYRIRVSAHDSGWTVS--- 459 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + V + D NDN P+F E +Y + E V +A++ ATD D G N + Y Sbjct: 460 ---TDVAVAVTDVNDNAPRFREPSYFLECPELPEVGSG--VARVAATDPDEGPNGQVFYL 514 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDY------EQVRSYRLVIRAQDGGSPSRSNTTQLL 244 + + F +D+++G++ + L Y + V+ D GSP + T + Sbjct: 515 L--KSPSEFFRVDAVTGEIFNKQPLRYLNGTGSVHANRHSFVVTCSDRGSPPLLSETTVT 572 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY-DADEGVNAELTYTMTDKDYTG 303 +++ D ND+ PRF ++ + V ++V +G +++V A D D G+N+ + Y +T ++ Sbjct: 573 VHVVDGNDHPPRFLSAGYSTPVPKDVSVGTRVIQVAAADDGDFGLNSRVEYLLTGQEPAA 632 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 L D +GWV + L + ++L VTA DGG PP SA AT Sbjct: 633 RFGL----DAETGWVSVAAPLTGDVDRTFRLSVTARDGGRPPLSAGATVRILVTEANAHT 688 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGG--------------- 406 F + VE+ E G V L A D+D E+ L Y G Sbjct: 689 PEFPRDRVRVEVPETLAVGAVVCVLAARDSDPAENGLLFYAFPPGTGVSYLAAEDEQEVS 748 Query: 407 -NTRGRFSITSQN---------GRGLITVAQPLDFKQERRYVLTVSATDSGGR---SDTA 453 +R + +T Q G ++VA PL +R + L+V+A D GGR S A Sbjct: 749 IKSRVEYLLTGQEPAARFGLDAETGWVSVAAPLTGDVDRTFRLSVTARD-GGRPPLSAGA 807 Query: 454 MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513 V+I +T+AN + P F V E +G V V++A D+D N + Y++S+ Sbjct: 808 TVRILVTEANAHTPEFPRDRVRVEVPETLAVGAVVCVLAARDADPAENGLLAYAVSA--- 864 Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 + + F +N TG +T LD ET + +TV+A DGG + + V + V+D Sbjct: 865 ----GNGEGLFAVNASTGVLTLAGALDYETGRSHEVTVSATDGGWAARTGFCAVTVDVLD 920 Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633 VNDN PVF YT + E+A GT V + ATDAD G N + Y L D + F +D Sbjct: 921 VNDNPPVFAGAEYTPEVAENAPSGTPVVTLRATDADSGPNAVVAYALHEADGD--LFAVD 978 Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693 P +GV+ T LD E+ H L A + + + V +++ +N+ P F S Sbjct: 979 PNTGVVSTQGFLDYETRREHRLTVKAFNVPDEERCAFAAVTVRVTGVNEYIPRFVSAAYG 1038 Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753 F +SE +P GT +G++ A D D GP+ V Y + G F +E G + + +D Sbjct: 1039 FEVSEAAPPGTPVGQVFAGDRDRGPDGEVSYLLFGESRRKGFRVERETG--QISVAGPLD 1096 Query: 754 LDYESPRKKYELVIRAASPPLWNDV-RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP 812 + E ++ + A P DV V + VT ++ N P + + + P G Sbjct: 1097 REREG-TVALRVLAKNAGPIRGADVDEVAVNVTVLDANDPPVFGAETYRVRISEGVPPGT 1155 Query: 813 FGR-VPAYDAD---VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVS 868 V A DAD + YR+ + ++ TG +T++ L+ + + V Sbjct: 1156 HVTFVGAADADSVPAWSRFSYRV-GPAGGDAFSVHPQTGQVTVTAPLDRETLPVYNLTVL 1214 Query: 869 VTD 871 D Sbjct: 1215 AVD 1217 Score = 265 bits (649), Expect = 1e-68 Identities = 241/818 (29%), Positives = 358/818 (43%), Gaps = 66/818 (8%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 FRID GA+ L E ++V V+ + SP +D S+T T+ D +P+ Sbjct: 117 FRIDPTRGAITAAEPLAGEAEVTFSVHVRDGGR-SPQAD--STTVTVRFAAAGD---FPR 170 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209 + + E V +PV + T + G S Y + GN F D L+G V Sbjct: 171 VRAEGRSFLFPESQQV-GSPVTV-VTGTSSRAGPLS---YHVASGNFGGAFHADQLTGQV 225 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269 + + LD+E ++ + + I A+D G P S+ +L + ++DVNDNAP F F ++EN Sbjct: 226 TTGRPLDFEAIQRFVVWIEARDAGFPPFSSYERLEVEVQDVNDNAPDFREDPFVAEIAEN 285 Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329 +P ++ V A D D G N +L Y + GN + I +G + ++ LDRE+ Sbjct: 286 LP-PRRVLAVAAADRDSGPNGQLDYGIV----AGNEEGHFAIHRATGEIRSTRPLDRESV 340 Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389 +Y+L V A+D GDPPRSATA F + + E+ P G V T Sbjct: 341 PRYRLTVRASDRGDPPRSATARVVVNVLDENDHSPRFSQ-LFSASVPENAPVGFTVTRAT 399 Query: 390 ATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR 449 +D DE + ++ F+I G ITV++PLD + RY + VSA DSG Sbjct: 400 TSDEDEGQNAVSRYSIADSGLPFAIDPSTGD--ITVSRPLDREDVARYRIRVSAHDSGWT 457 Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509 T V + +TD N+ AP F Y E +G+ V V+ATD D G N Q+ Y L Sbjct: 458 VSTD-VAVAVTDVNDNAPRFREPSYFLECPELPEVGSGVARVAATDPDEGPNGQVFYLLK 516 Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG------YLLTVTARDGGVPSLSD 563 S + F ++ TG I + L +G + VT D G P L Sbjct: 517 SP---------SEFFRVDAVTGEIFNKQPLRYLNGTGSVHANRHSFVVTCSDRGSPPLLS 567 Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT-DADVGLNGRIHYELDP 622 T V + VVD ND+ P F Y+ + +D VGT V QV A D D GLN R+ Y L Sbjct: 568 ETTVTVHVVDGNDHPPRFLSAGYSTPVPKDVSVGTRVIQVAAADDGDFGLNSRVEYLLTG 627 Query: 623 KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND 682 ++ F +D +G + L + T L A DGG PP S+ V I + + N Sbjct: 628 QE-PAARFGLDAETGWVSVAAPLTGDVDRTFRLSVTARDGGRPPLSAGATVRILVTEANA 686 Query: 683 SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG--------DDSNS 734 P F D + + E +G + + A D D N ++ Y+ G +D Sbjct: 687 HTPEFPRDRVRVEVPETLAVGAVVCVLAARDSDPAENGLLFYAFPPGTGVSYLAAEDEQE 746 Query: 735 FSLETRQG--SDKAELVTMVDLDYES------------PRKKYELVIRA---ASPPLWND 777 S+++R E LD E+ + + L + A PPL Sbjct: 747 VSIKSRVEYLLTGQEPAARFGLDAETGWVSVAAPLTGDVDRTFRLSVTARDGGRPPLSAG 806 Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRV-PAYDADVTDK--LQYRILSG 834 V ILVT+ N + P ++ + VG V A DAD + L Y + +G Sbjct: 807 ATVRILVTEANAHTPEFPRDRVRV-EVPETLAVGAVVCVLAARDADPAENGLLAYAVSAG 865 Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 N L +N +TG +TL+ L+ + + VS TDG Sbjct: 866 NGEGLFAVNASTGVLTLAGALDYETGRSHEVTVSATDG 903 Score = 229 bits (559), Expect = 1e-57 Identities = 191/633 (30%), Positives = 294/633 (46%), Gaps = 49/633 (7%) Query: 174 IKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233 + TD D G NS + +++ G +++ +F ID G ++ + L E ++ + +R DGG Sbjct: 92 VTVTDPDTGPNSELHFSLSGSHSE-RFRIDPTRGAITAAEPLAGEAEVTFSVHVR--DGG 148 Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293 ++++T + + D PR E+ +G + V + G L+ Sbjct: 149 RSPQADSTTVTVRFAAAGD-FPRVRAEGRSFLFPESQQVGSPVTVVTGTSSRAG---PLS 204 Query: 294 YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353 Y + +GN D +G V T LD E ++ + + A D G PP S+ Sbjct: 205 YHVA----SGNFGGAFHADQLTGQVTTGRPLDFEAIQRFVVWIEARDAGFPPFSSYERLE 260 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGR 411 F + E+AE+ PP V+ + A D D + +L Y I GN G Sbjct: 261 VEVQDVNDNAPDFREDPFVAEIAENLPP-RRVLAVAAADRDSGPNGQLDYGIVAGNEEGH 319 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVF 469 F+I G I +PLD + RY LTV A+D G RS TA V +N+ D N+++P F Sbjct: 320 FAI--HRATGEIRSTRPLDRESVPRYRLTVRASDRGDPPRSATARVVVNVLDENDHSPRF 377 Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 ++ASV E+AP+G TV + +D D G NA +S ++A F I+P Sbjct: 378 SQL-FSASVPENAPVGFTVTRATTSDEDEGQNA---------VSRYSIADSGLPFAIDPS 427 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589 TG IT ++ LDRE ++ Y + V+A D G + +TDV ++V DVNDN P F++ Y Sbjct: 428 TGDITVSRPLDREDVARYRIRVSAHDSG---WTVSTDVAVAVTDVNDNAPRFREPSYFLE 484 Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL---- 645 E VG+ V++V ATD D G NG++ Y L K E F +D +G I + L Sbjct: 485 CPELPEVGSGVARVAATDPDEGPNGQVFYLL--KSPSE-FFRVDAVTGEIFNKQPLRYLN 541 Query: 646 DRESVAT--HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703 SV H D G+PP S V + + D ND PP F S + + ++ +G Sbjct: 542 GTGSVHANRHSFVVTCSDRGSPPLLSETTVTVHVVDGNDHPPRFLSAGYSTPVPKDVSVG 601 Query: 704 TTIGEI-RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762 T + ++ A D D G N+ V Y + G + + F L+ G D+D + Sbjct: 602 TRVIQVAAADDGDFGLNSRVEYLLTGQEPAARFGLDAETGWVSVAAPLTGDVD-----RT 656 Query: 763 YELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792 + L + A PPL V ILVT+ N + P Sbjct: 657 FRLSVTARDGGRPPLSAGATVRILVTEANAHTP 689 Score = 213 bits (520), Expect = 6e-53 Identities = 170/611 (27%), Positives = 279/611 (45%), Gaps = 35/611 (5%) Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329 +P G + V D D G N+EL ++++ G+ IDP G + + L E + Sbjct: 83 LPAGLFVFAVTVTDPDTGPNSELHFSLS-----GSHSERFRIDPTRGAITAAEPLAGEAE 137 Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389 + + V DGG P++ + T G+ + E + G+PV +T Sbjct: 138 VTFSVHVR--DGGRSPQADSTTVTVRFAAAGDFPRVRAEGRSFL-FPESQQVGSPVTVVT 194 Query: 390 ATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR 449 T + L Y + GN G F G+ +T +PLDF+ +R+V+ + A D+G Sbjct: 195 GTSS-RAGPLSYHVASGNFGGAFHADQLTGQ--VTTGRPLDFEAIQRFVVWIEARDAGFP 251 Query: 450 --SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507 S +++ + D N+ AP F P+ A + E+ P VL V+A D D G N Q+ Y Sbjct: 252 PFSSYERLEVEVQDVNDNAPDFREDPFVAEIAENLP-PRRVLAVAAADRDSGPNGQLDYG 310 Query: 508 LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567 + + NE + F I+ TG I + + LDRE++ Y LTV A D G P S T V Sbjct: 311 IVA--GNE-----EGHFAIHRATGEIRSTRPLDRESVPRYRLTVRASDRGDPPRSATARV 363 Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627 ++V+D ND+ P F Q L++A++ E+A VG +V++ +D D G N Y + Sbjct: 364 VVNVLDENDHSPRFSQ-LFSASVPENAPVGFTVTRATTSDEDEGQNAVSRYSIADSGLP- 421 Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687 F IDP++G I ++ LDRE VA + ++ A D G + V + + D+ND+ P F Sbjct: 422 --FAIDPSTGDITVSRPLDREDVARYRIRVSAHDSGWTVSTD---VAVAVTDVNDNAPRF 476 Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747 E +G+ + + A DPDEGPN V Y +K + T + +K Sbjct: 477 REPSYFLECPELPEVGSGVARVAATDPDEGPNGQVFYLLKSPSEFFRVDAVTGEIFNKQP 536 Query: 748 LVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY 804 L ++ ++ V+ + SPPL ++ V + V D ND+ P Sbjct: 537 L-RYLNGTGSVHANRHSFVVTCSDRGSPPLLSETTVTVHVVDGNDHPPRFLSAGYSTPVP 595 Query: 805 KDCFPVGPFGRVPAY---DADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPK 861 KD +V A D + +++Y + A L+ TG ++++ L +V + Sbjct: 596 KDVSVGTRVIQVAAADDGDFGLNSRVEYLLTGQEPAARFGLDAETGWVSVAAPLTGDVDR 655 Query: 862 LATMEVSVTDG 872 + V+ DG Sbjct: 656 TFRLSVTARDG 666 Score = 44.8 bits (101), Expect = 0.035 Identities = 17/39 (43%), Positives = 19/39 (48%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C C APC+NG C DL + C C EG GK C Sbjct: 1594 CETDVDECLPAPCHNGGACRDLVGAFACSCPEGFGGKAC 1632 >UniRef50_Q60YX0 Cluster: Putative uncharacterized protein CBG18050; n=1; Caenorhabditis briggsae|Rep: Putative uncharacterized protein CBG18050 - Caenorhabditis briggsae Length = 4339 Score = 310 bits (762), Expect = 3e-82 Identities = 346/1393 (24%), Positives = 583/1393 (41%), Gaps = 135/1393 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +++LD ND++P F + ++ E A+ GT+V A D+D + + ++ LV D Sbjct: 2702 LDILDVNDNAPAFHGDYDKLTISEDATVGTSVTIFSAMDRDDSPSGRIRFS--LVNKD-- 2757 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P F ++G SG L A LDRE Y ++ +ATD+ +D Sbjct: 2758 -PH----------------FEMNGDSGWLTVAAPLDRETQDLYQLIARATDEGGFNTDL- 2799 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + TI VN D ND+ P+F + + D D+ + N +I D D+ N+ Sbjct: 2800 --SFTISVN--DVNDSPPKFEKDEF----DVDLLLPSNALILHFDIKDEDLAPNNHSLLF 2851 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I GN + F IDS ++ L + E + Y L I A DG +++ L + DV Sbjct: 2852 ISEGNEEGVFWIDS-ENNLLLKRPEIVENKKEYSLKIIAFDGVFEAKTLVKIHLKSKEDV 2910 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 P ++ S+ + + G ++ L T K + Sbjct: 2911 KTRCPDVEKTVILPESSKKGTVVF------------GESSLLGPNTTFKLIEEGAENAFV 2958 Query: 311 IDPRSGWVYTS--GQLDRETQAKYQLLVTATDGGDP--PRSATATXXXXXXXXXXXXXXF 366 ++ R+G + GQ+D E +++L+ G D T Sbjct: 2959 MNFRNGIIKVKEVGQIDYEKTQEFELIRLTIQGKDELCKERITVKIENLNDNPPKIKEKS 3018 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 + E L + + + A DAD D+ +H+ + + F I +G ++TV Sbjct: 3019 VYVSIEENLPTSQDSRQYLTRIAAEDADSDD-IHFRLLDDFNK-TFEIDEFSG--VVTVL 3074 Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 +PLD + + LT A+D G D A++ + + D N+ AP FE + Y+ V E +G Sbjct: 3075 KPLDSESVSSFNLTAIASD-GNFEDKAIIVVTVIDKNDNAPTFEKSTYSMKVMESEAVGY 3133 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 + + A D N I YSL + N+ V+ +N Q G +T + LD ET+S Sbjct: 3134 ELARLQAFGGDT--NETIEYSLKASDHNKFVS-------LNAQNGVLTLAQPLDFETIST 3184 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 LTV A+D G+P L VEISV+D NDN P F+++ YT + E++ VG V V A Sbjct: 3185 LRLTVIAKDSGIPPLESVAQVEISVMDENDNAPKFEKEKYTGKVKENSKVGEKVLTVKAV 3244 Query: 607 DADVGLNGRIHYELD------PKDREEGSFVIDP----ASGVIRTNKALDRESVATHDLK 656 DAD G + YEL+ D + V P A+G + N+ +D E ++LK Sbjct: 3245 DADSEHFGAVSYELELIADKASDDSLPTTSVTPPFSINANGDVLINQPIDYEKTKKYNLK 3304 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 +A DGG PP S ++ I + D ND+ PVF+ +T + E IG + + D D Sbjct: 3305 LIAKDGGRPPLVSEALLDIHVGDENDNAPVFDDCNMTAVVQEGESIGHKVLKFSISDLD- 3363 Query: 717 GPNAVVHYSIK-GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW 775 GP ++++ GD + SF + +DK EL+T L++ + K VI + Sbjct: 3364 GPTNGAPFTVEIQGDGAKSFKV-----NDKLELLTAKKLEHRNKDKYLLTVIAKDTKGKS 3418 Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK---LQYRIL 832 D + + + + +AP MK +I N ++ P G GR+ A+D D D+ L++ I+ Sbjct: 3419 TDCPLTVFIRQASRHAPTMKPMKIQVNTLQNELPEGVIGRLKAFDEDEEDQNGLLRFGIV 3478 Query: 833 SGNNAN-LILLNET--TGSMTLSPQLNT-----NVPK-LATMEVSVTDGVNEIKAMMQLS 883 G+ + + + E+ T + P ++P+ L T V+V+DG + +++ Sbjct: 3479 EGSTQSPRVQMQESRPTHLFRIDPTTGDIWSDHSIPQGLHTFNVTVSDGKFTTVSYVEVQ 3538 Query: 884 VRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKEN-IYIFSVQDDTDV 942 V I +++ +++++R+ MT E F+ + F ++ + EN I + SVQ Sbjct: 3539 VNSIDNDVIDHAVSIRIRSMTVEDFMKNHVKEFRRIISHHLNLNDENSIQLISVQQ-VPS 3597 Query: 943 TGNILNVSFSARRPDAEVGVA-----GDPSPHYSPTHLRERVYLHRTTLARLATVQVLPF 997 T + N S R P +V V G + P H+ R+ + + Sbjct: 3598 TDSARNRR-SKRGPSEDVEVLMTAQRGHGRGYLKPDHVYSRLKNDFQNMNDQSQRMRYQL 3656 Query: 998 DDNICVHEPCLNFEECLTVLKFGNASGF-VNSDSVLFRPIYPVTSFTCQCPEGFTGVNCE 1056 +C CL EC V++ + S V+++ F + C CP+GF G CE Sbjct: 3657 ITEMCTTGVCLR-GECREVIELIDDSWTKVSTEEFSFVSPFHSRFAQCLCPDGFGGKRCE 3715 Query: 1057 ---TILTKASCEVDGD--GSICRSGSQCVARREGGILCQGCSIDAAYTTAVCELRARSFP 1111 +K+ CE S+ S +CV G+ C + + C L Sbjct: 3716 IETNQCSKSPCEQWQMCIPSVFNSTFECVCPL--GMEGDRCLVPSCKNDGKC-LEEAELS 3772 Query: 1112 VSS---FLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRGG 1168 V F + R+ L+++ T + +G+++++ RHD+ L LV+ A Sbjct: 3773 VGGDGYFEISLSNEIESRMELEIELKTTSPNGIIMWS---RGRHDYHMLRLVNGSA---- 3825 Query: 1169 GPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMIL--DDCDKVLSLAGAAD 1226 ++ + G G +T + + DG WH + I R M + D ++ S G+ Sbjct: 3826 ----QYHWDAGTGTGIVTSKTLIVDGQWHRITISRRQRRTRMTVDDDGLEEAFSPVGSTV 3881 Query: 1227 FGLKYACANFT--RKVLPARCEIPTETCHRFLDLTG--------PLQIGGL-PNIPSSFQ 1275 L KV + C R + + G +++ G+ P + Sbjct: 3882 VNLHRYSQKLVLGAKVENGQLTDGISGCFRTISIDGIKVLKTRQGMKLFGVQPGCSALTS 3941 Query: 1276 VKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAPCYNGAECSDLWDTY 1335 D + H + C CSS PC G +C ++ Y Sbjct: 3942 SPCNDLPCKHGGTCVSHGKSQFVCQCTSRYSGDTCEIDLEPCSSTPCPTGIQCIPFYNDY 4001 Query: 1336 ICDCKEGHTGKDC 1348 +C C G TGK C Sbjct: 4002 LCKCPNGFTGKHC 4014 Score = 257 bits (629), Expect = 4e-66 Identities = 241/909 (26%), Positives = 413/909 (45%), Gaps = 70/909 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + ++D N+HSPV+ + + G +L + ATDQD G N V Y I + Sbjct: 475 VEIVDSNNHSPVWSAKWMRQAPIPLGKPGDVLLKVDATDQDEGDNGRVVYKINSEIPFEI 534 Query: 71 NPEDAXXXXXXXXXXVQD----VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 N + V+ ID G L+R S + Y K + PV Sbjct: 535 NANTGEITLIEVPTKSNNWMVTVWAID--LGLPLSRMSA--LNLMFYKNGTKVPAKPKPV 590 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 + S +N + P FS V V ED + V+AK++++D D G N Sbjct: 591 IIQES-----------ENKHSPVFSSFPEVVEVTEDAPI--GTVVAKLQSSDEDAGYNGL 637 Query: 187 IRYAI--IGGNTQMQFSIDSLSGDVSLVKTL-----DYEQVRSYRLVIRAQDGGSPSRSN 239 IRY I I G++ S+D SG++++ L + ++V ++ + A D G+P +S Sbjct: 638 IRYVIQDISGSSHEILSVDEQSGEITVASDLTLLMKEKQKVVEIQVKVSAVDAGTPVKSA 697 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 T + + I+DVN+++P F + ++SE+ G I + A D D G N ++ +++ + Sbjct: 698 TRTMKLRIKDVNNHSPHFDEPSYYLAISESEKPGKDIFKATANDFDGGNNGKIKFSLGNN 757 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 +V I+I+P++G + LDRE Q + + A+D GDP R Sbjct: 758 GAESSV---ISIEPKTGIIKLLNPLDREEQDVHYFSIIASDDGDPARITVTNLTITVDDV 814 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG 419 + + + ED P G V L A D D + + F + +G Sbjct: 815 NDNAPRCVSQVAKARIPEDLPHGAFVACLAAFDEDVGLNSKLKFLLNAEKVPFRVDHHSG 874 Query: 420 RGLITVAQ-PLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDA--NNYAPVFENAPY 474 L PLD+++ + L++ D G S T +++ + D + A F++ Sbjct: 875 CLLGNSPDVPLDYQKTPNFNLSIEVADHGEPMLSTTCFLEVELVDVPHKHLAIEFDDVAK 934 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 ASV+E++ IGT V++V A ++G ++ + + + + + Q G + Sbjct: 935 EASVYENSEIGTEVIMVEA--KEMGDEQKVK---AENLEYRIIGGNGWPYFSIDQKGTVR 989 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSD-----TTDVEISVVDVNDNEPVFKQQLYTAN 589 T +LDRE S Y +TV ARD D V I ++D ND+ PV K +Y A+ Sbjct: 990 TTHILDREKRSAYWITVEARDAKTDFYKDPRRRAVLHVFIRILDRNDHRPVAKSAMYIAS 1049 Query: 590 IMEDALVGTSVSQVGATDA-DVGLNGR--IHYELDPKDREEGSFVIDPASGVIRTN--KA 644 ++E++ + +V ATDA D+ +G + ++++ D + F ID ASG I T+ + Sbjct: 1050 VLENSPANVVIVKVEATDADDIDNDGAAPLTFKIERGD-PQSFFRIDLASGYITTSGIRR 1108 Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 LDRE A H+L DGG P S V+V +K+ D ND+ P F + + Y + IG Sbjct: 1109 LDREKQAEHELWISICDGGEPQLCSNVVVIVKVLDENDNAPTF-TQAMHHYNVRSKHIG- 1166 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGD-----DSNSFSLETRQ-GSDKAELVTMVDLDYES 758 + I A D DEG N+ + Y++ GD D N + + SD++ +T+ D+ S Sbjct: 1167 KLCRIFAVDIDEGENSHLSYNVTEGDPRFSIDENGNIMTSEAIHSDESYALTLQATDHGS 1226 Query: 759 PRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF-NNYKDCFPVG-PFGRV 816 P +++ AA+ + V ++ PV+ + + D VG G++ Sbjct: 1227 PSQQF-----AATRVVLTAVGSSQKTKKSKNSPPVISGKKSDYVIPISDADQVGLTVGKL 1281 Query: 817 PAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG--VN 874 A DAD D L + I SG++ ++ + + TG + L+ ++ + +SVTDG V+ Sbjct: 1282 EATDAD-GDDLWWNIFSGDSDSVFDVRQDTGQLLLAKKVELLKRGELRLNISVTDGQDVD 1340 Query: 875 EIKAMMQLS 883 ++Q+S Sbjct: 1341 HTTVIIQVS 1349 Score = 225 bits (551), Expect = 1e-56 Identities = 208/795 (26%), Positives = 364/795 (45%), Gaps = 85/795 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 ++V+D ND P F + Y S+ E A G TVL + ATD+D +N +EY++ L Sbjct: 2495 LSVIDINDKPPFFVLPFYSTSIPETAKEGDTVLMVSATDED--ENDTIEYSL-------L 2545 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + ++ F + R G + L+ + ++ +KATD A+P Sbjct: 2546 DGGES------------QFFSVHPRQGTITVSKKLEHKAGVTLSLTIKATDSANPPH--- 2590 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +T T+ +N+ ++ P+FS Y V ED + D V+ ++ + ++ +R+ Sbjct: 2591 HATTTVEINVASESVRVPRFSNSHYLFFVPEDADIGD--VVGSVQQMETEI---DEVRFT 2645 Query: 191 IIGG----NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 I+ G ++ + FS++ +G + + +LD E+ + +++ IRA G T L + Sbjct: 2646 IVPGSEVSDSLLPFSVERSTGKIIVKSSLDRERRKQWKMTIRADAAGGVHAITTVTL--D 2703 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 I DVNDNAP F+ + ++SE+ +G S+ A D D+ + + +++ +K D Sbjct: 2704 ILDVNDNAPAFHGDYDKLTISEDATVGTSVTIFSAMDRDDSPSGRIRFSLVNK------D 2757 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 ++ SGW+ + LDRETQ YQL+ ATD G + + F Sbjct: 2758 PHFEMNGDSGWLTVAAPLDRETQDLYQLIARATDEGG--FNTDLSFTISVNDVNDSPPKF 2815 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLIT 424 +++V+L P ++ D D +N I+ GN G F I S+N + Sbjct: 2816 EKDEFDVDLL--LPSNALILHFDIKDEDLAPNNHSLLFISEGNEEGVFWIDSENN---LL 2870 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 + +P + ++ Y L + A D + T +V+I++ + + T + E + Sbjct: 2871 LKRPEIVENKKEYSLKIIAFDGVFEAKT-LVKIHLKSKEDVKTRCPDVEKTVILPESSKK 2929 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL--LDRE 542 GT VV S +G N T+ L E + A FV+N + G I ++ +D E Sbjct: 2930 GT---VVFGESSLLGPNT--TFKLIEEGAENA-------FVMNFRNGIIKVKEVGQIDYE 2977 Query: 543 -TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS-- 599 T L+ +T + G L + + + ++NDN P K++ +I E+ Sbjct: 2978 KTQEFELIRLTIQ--GKDELCKER-ITVKIENLNDNPPKIKEKSVYVSIEENLPTSQDSR 3034 Query: 600 --VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 ++++ A DAD + IH+ L D +F ID SGV+ K LD ESV++ +L A Sbjct: 3035 QYLTRIAAEDAD---SDDIHFRL--LDDFNKTFEIDEFSGVVTVLKPLDSESVSSFNLTA 3089 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 +A DG ++ I+ + + D ND+ P FE + + E+ +G + ++A D Sbjct: 3090 IASDGNFEDKA---IIVVTVIDKNDNAPTFEKSTYSMKVMESEAVGYELARLQAFGGD-- 3144 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND 777 N + YS+K D + SL + G L +D + S + + + PPL + Sbjct: 3145 TNETIEYSLKASDHNKFVSLNAQNG--VLTLAQPLDFETISTLRLTVIAKDSGIPPLESV 3202 Query: 778 VRVEILVTDVNDNAP 792 +VEI V D NDNAP Sbjct: 3203 AQVEISVMDENDNAP 3217 Score = 193 bits (470), Expect = 7e-47 Identities = 212/893 (23%), Positives = 379/893 (42%), Gaps = 78/893 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND+ PVF + +A V + A SG + + ATD D + ++ + + + Sbjct: 2273 VMIEDVNDNMPVFIRPEVKAEVSDAAISGQFITIMSATDMDT--TSSLDDPNQKLLYKIV 2330 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + ++ V RI+ LT S D +KV V V TD Sbjct: 2331 DGDETLFNISPSTGEVSLARRIEQED---LTSESEDPKKV----VNVSVTD------GMF 2377 Query: 131 SSTATIHVNIIDDNDNYP--QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 ++ A + V I+ P +F + Y + E+ V + ++ T A G +R Sbjct: 2378 TAYAKLVVGILRSGKMQPPPKFEQSHYVATALENTIVNKSALL-----TVAVKGGIPPLR 2432 Query: 189 YAI--------IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240 Y++ +ID +G + + + L+Y + Y++ + +D R Sbjct: 2433 YSLGPAAYSNSSSSKDSWPVAIDKKTGRIHVSRVLNYHNDKLYQIPLVVED--VTRRRAF 2490 Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 + L +++ D+ND P F + S+ E G +++ V A D DE N + Y++ D Sbjct: 2491 STLTLSVIDINDKPPFFVLPFYSTSIPETAKEGDTVLMVSATDEDE--NDTIEYSLLD-- 2546 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 G ++ PR G + S +L+ + L + ATD +PP AT T Sbjct: 2547 --GGESQFFSVHPRQGTITVSKKLEHKAGVTLSLTIKATDSANPPHHATTTVEINVASES 2604 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGN--TRGRFSITSQN 418 F Y + ED G V ++ + + D + + I G+ + + + Sbjct: 2605 VRVPRFSNSHYLFFVPEDADIGDVVGSVQQMETEIDE-VRFTIVPGSEVSDSLLPFSVER 2663 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASV 478 G I V LD ++ +++ +T+ A +GG V ++I D N+ AP F ++ Sbjct: 2664 STGKIIVKSSLDRERRKQWKMTIRADAAGGVHAITTVTLDILDVNDNAPAFHGDYDKLTI 2723 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 EDA +GT+V + SA D D + +I +SL + D F +N +G +T Sbjct: 2724 SEDATVGTSVTIFSAMDRDDSPSGRIRFSL---------VNKDPHFEMNGDSGWLTVAAP 2774 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 LDRET Y L A D G + ISV DVND+ P F++ + +++ + Sbjct: 2775 LDRETQDLYQLIARATDEG--GFNTDLSFTISVNDVNDSPPKFEKDEFDVDLLLPS--NA 2830 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 + D D+ N + + EEG F ID + ++ + E+ + LK + Sbjct: 2831 LILHFDIKDEDLAPNNHSLLFIS-EGNEEGVFWIDSENNLLLKRPEI-VENKKEYSLKII 2888 Query: 659 AIDGGTPPQSSTVIVHIKI-EDINDSPPVFESDCLTFYISENSPIGTTI-GEIRAHDPDE 716 A D G + V +H+K ED+ P E T + E+S GT + GE Sbjct: 2889 AFD-GVFEAKTLVKIHLKSKEDVKTRCPDVEK---TVILPESSKKGTVVFGESSL----L 2940 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN 776 GPN +G + N+F + R G K + V +D + + L I+ L Sbjct: 2941 GPNTTFKLIEEGAE--NAFVMNFRNGIIKVKEVGQIDYEKTQEFELIRLTIQ-GKDELCK 2997 Query: 777 DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-----FGRVPAYDADVTDKLQYRI 831 + R+ + + ++NDN P +K+ + ++ + ++ P R+ A DAD +D + +R+ Sbjct: 2998 E-RITVKIENLNDNPPKIKE-KSVYVSIEENLPTSQDSRQYLTRIAAEDAD-SDDIHFRL 3054 Query: 832 LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884 L N ++E +G +T+ L++ + +DG E KA++ ++V Sbjct: 3055 LDDFN-KTFEIDEFSGVVTVLKPLDSESVSSFNLTAIASDGNFEDKAIIVVTV 3106 Score = 192 bits (468), Expect = 1e-46 Identities = 193/769 (25%), Positives = 326/769 (42%), Gaps = 77/769 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND++P Q +A + E G V L A D+D+G N+++++ L Sbjct: 809 ITVDDVNDNAPRCVSQVAKARIPEDLPHGAFVACLAAFDEDVGLNSKLKFL--------L 860 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS---LDREKVARYTVLVKATDQASPVS 127 N E FR+D SG LL + LD +K + + ++ D P+ Sbjct: 861 NAEKVP-------------FRVDHHSGCLLGNSPDVPLDYQKTPNFNLSIEVADHGEPM- 906 Query: 128 DRLSSTATIHVNIIDDNDNYP--QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 LS+T + V ++D + +F + SV E+ + ++ + K + + Sbjct: 907 --LSTTCFLEVELVDVPHKHLAIEFDDVAKEASVYENSEIGTEVIMVEAKEMGDEQKVKA 964 Query: 186 A-IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS-----PSRSN 239 + Y IIGGN FSID G V LD E+ +Y + + A+D + P R Sbjct: 965 ENLEYRIIGGNGWPYFSIDQ-KGTVRTTHILDREKRSAYWITVEARDAKTDFYKDPRRRA 1023 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 + I I D ND+ P ++++ SV EN P IV+V+A DAD+ ++ + +T K Sbjct: 1024 VLHVFIRILDRNDHRPVAKSAMYIASVLENSPANVVIVKVEATDADD-IDNDGAAPLTFK 1082 Query: 300 DYTGNVDLPITIDPRSGWVYTSG--QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357 G+ ID SG++ TSG +LDRE QA+++L ++ DGG+P + Sbjct: 1083 IERGDPQSFFRIDLASGYITTSGIRRLDREKQAEHELWISICDGGEPQLCSNVVVIVKVL 1142 Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ 417 F + + + D E++ L Y +T G+ R FSI + Sbjct: 1143 DENDNAPTFTQAMHHYNVRSKHIGKLCRIFAVDIDEGENSHLSYNVTEGDPR--FSI-DE 1199 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT-AMVQINIT---------DANNYAP 467 NG + + A + Y LT+ ATD G S A ++ +T + N P Sbjct: 1200 NGNIMTSEA----IHSDESYALTLQATDHGSPSQQFAATRVVLTAVGSSQKTKKSKNSPP 1255 Query: 468 VF--ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525 V + + Y + + +G TV + ATD+D + +++ S S D F Sbjct: 1256 VISGKKSDYVIPISDADQVGLTVGKLEATDAD---GDDLWWNIFSGDS-------DSVFD 1305 Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585 + TG + K ++ L ++ DG D T V I V P F Sbjct: 1306 VRQDTGQLLLAKKVELLKRGELRLNISVTDG---QDVDHTTVIIQVSRQISQRPAFSANR 1362 Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD-REEGSFVIDPASGVIRTNKA 644 Y + E VGT + + AT ++G ++ D E ++P+SG + + Sbjct: 1363 YDTLVSERVAVGTQIHTLKATGENLGTKPLVYSLFSIDDIAMEDKIRVEPSSGNVIVMEP 1422 Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 LD E VA+ V + S +I +++ D ND+ P F ++ EN + Sbjct: 1423 LDYE-VASQIRAVVQVQQANMKSFSKLI--LEVTDENDNAPYFVEHTAWAFVDENDSVDD 1479 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753 + + A D D+ N ++ YSI G++ + F +++ G + L ++D Sbjct: 1480 VLATVTAFDRDQDDNGIITYSIVSGNEESLFKIDSHSG--EVRLARLID 1526 Score = 173 bits (420), Expect = 8e-41 Identities = 211/910 (23%), Positives = 378/910 (41%), Gaps = 88/910 (9%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATD-QDIGKNAEVEYTIELV 65 +H I +LD NDH PV + Y ASV E + + ++ ++ATD DI + T ++ Sbjct: 1025 LHVFIRILDRNDHRPVAKSAMYIASVLENSPANVVIVKVEATDADDIDNDGAAPLTFKIE 1084 Query: 66 TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRA--SLDREKVARYTVLVKATDQA 123 D Q FRID SG + T LDREK A + + + D Sbjct: 1085 RGDP-----------------QSFFRIDLASGYITTSGIRRLDREKQAEHELWISICDGG 1127 Query: 124 SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183 P +L S + V ++D+NDN P F++ + +V + +I A D D G Sbjct: 1128 EP---QLCSNVVVIVKVLDENDNAPTFTQAMHHYNVRSK----HIGKLCRIFAVDIDEGE 1180 Query: 184 NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS-NTTQ 242 NS + Y + G+ + FSID +G++ + + ++ SY L ++A D GSPS+ T+ Sbjct: 1181 NSHLSYNVTEGDPR--FSIDE-NGNIMTSEAIHSDE--SYALTLQATDHGSPSQQFAATR 1235 Query: 243 LLINI------RDVNDNAPRFYT---SLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293 +++ + N+P + S + +S+ +G ++ +++A DAD +L Sbjct: 1236 VVLTAVGSSQKTKKSKNSPPVISGKKSDYVIPISDADQVGLTVGKLEATDAD---GDDLW 1292 Query: 294 YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353 + + ++G+ D + +G + + +++ + + +L ++ TDG D + T Sbjct: 1293 WNI----FSGDSDSVFDVRQDTGQLLLAKKVELLKRGELRLNISVTDGQDVDHT---TVI 1345 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR-LHYEITG-GNTRGR 411 F +Y+ ++E GT + TL AT + + L Y + + Sbjct: 1346 IQVSRQISQRPAFSANRYDTLVSERVAVGTQIHTLKATGENLGTKPLVYSLFSIDDIAME 1405 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN 471 I + G + V +PLD++ + V + +S + ++ + +TD N+ AP F Sbjct: 1406 DKIRVEPSSGNVIVMEPLDYEVASQIRAVVQVQQANMKSFSKLI-LEVTDENDNAPYFVE 1464 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 A V E+ + + V+A D D N ITYS+ S NE + F I+ +G Sbjct: 1465 HTAWAFVDENDSVDDVLATVTAFDRDQDDNGIITYSIVS--GNE-----ESLFKIDSHSG 1517 Query: 532 AITTNKLLDRETMSGY-LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590 + +L+D E +L + A D SL D + I + F +++Y ++ Sbjct: 1518 EVRLARLIDPEMQHVVSILRIRASDSATISLKDELTLHIKSSKLTSENAKFDRKVYQTSL 1577 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES- 649 + GT V + +G I ++L+P F + SG + K + +E Sbjct: 1578 HDSTRPGTPVLVLNVLH-----HGAITFKLEPNCT---FFDVHTLSGAVHLAKWITKEKQ 1629 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 + T + A ++G Q T + KI N PVF + EN G+++ Sbjct: 1630 LKTLECTAYVVNGDG--QQDTAKIVAKIIRTNQHSPVFRKQVYRGTVRENMEPGSSVLSN 1687 Query: 710 R-------AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762 R A D D G N +V Y + D F+++ G+ + D + Sbjct: 1688 RHLPLVLLASDEDSGSNGLVGYRMLSKADEEMFTVDQYSGAVRTN--KAFDFEKIKEHSF 1745 Query: 763 YELVIRAASPPLWN--DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD 820 Y PP + V + ++D ND P + G + D Sbjct: 1746 YVQAFDMGQPPRQSLMPALVVVTISDENDETPKFASQSLDVIMLLPTASQAVVGGQMSDD 1805 Query: 821 ADVTDKLQYRILSGNNANLILLNETTGSMTLSP-QLNTNVPKLATMEVSVTDGVNEIKAM 879 AD L+Y I ++++ ++ TG +++ + TN K +EV VTDG Sbjct: 1806 ADSIGTLRYYI--KDSSSPFSVDSKTGIVSVKDFKAFTNEKKHYNVEVFVTDGNQSTSYT 1863 Query: 880 MQLSVRLITE 889 M+++ E Sbjct: 1864 MKVTTTSTAE 1873 Score = 171 bits (415), Expect = 3e-40 Identities = 219/877 (24%), Positives = 379/877 (43%), Gaps = 90/877 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ + D N+HSP F+ Y ++ E G + A D D G N ++++++ A++ Sbjct: 702 KLRIKDVNNHSPHFDEPSYYLAISESEKPGKDIFKATANDFDGGNNGKIKFSLGNNGAES 761 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 V I+ ++G + LDRE+ + + A+D P R Sbjct: 762 ------------------SVISIEPKTGIIKLLNPLDREEQDVHYFSIIASDDGDPA--R 801 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 ++ T + + + D NDN P+ + + ED+ +A + A D DVG NS +++ Sbjct: 802 ITVT-NLTITVDDVNDNAPRCVSQVAKARIPEDL--PHGAFVACLAAFDEDVGLNSKLKF 858 Query: 190 AIIGGNTQMQFSIDSLSGDV---SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 + ++ F +D SG + S LDY++ ++ L I D G P S T L + Sbjct: 859 LL--NAEKVPFRVDHHSGCLLGNSPDVPLDYQKTPNFNLSIEVADHGEPMLSTTCFLEVE 916 Query: 247 IRDVNDN--APRFYTSLFQESVSENVPIGYSIVRVQAYDA--DEGVNAE-LTYTMTDKDY 301 + DV A F + SV EN IG ++ V+A + ++ V AE L Y + Sbjct: 917 LVDVPHKHLAIEFDDVAKEASVYENSEIGTEVIMVEAKEMGDEQKVKAENLEYRIIG--- 973 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG-----GDPPRSATATXXXXX 356 GN +ID + G V T+ LDRE ++ Y + V A D DP R A Sbjct: 974 -GNGWPYFSID-QKGTVRTTHILDREKRSAYWITVEARDAKTDFYKDPRRRAVLHVFIRI 1031 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DN----RLHYEITGGNTRGR 411 Y + E+ P +V + ATDAD+ DN L ++I G+ + Sbjct: 1032 LDRNDHRPVAKSAMYIASVLENSPANVVIVKVEATDADDIDNDGAAPLTFKIERGDPQSF 1091 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVF 469 F I +G + + LD +++ + L +S D G +V + + D N+ AP F Sbjct: 1092 FRIDLASGYITTSGIRRLDREKQAEHELWISICDGGEPQLCSNVVVIVKVLDENDNAPTF 1151 Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 A + +V IG + + A D D G N+ ++Y+ V D +F I+ + Sbjct: 1152 TQAMHHYNV-RSKHIG-KLCRIFAVDIDEGENSHLSYN---------VTEGDPRFSID-E 1199 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLS-DTTDVEISVVDVN-------DNEPVF 581 G I T++ + + Y LT+ A D G PS T V ++ V + ++ PV Sbjct: 1200 NGNIMTSEAIHSD--ESYALTLQATDHGSPSQQFAATRVVLTAVGSSQKTKKSKNSPPVI 1257 Query: 582 --KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639 K+ Y I + VG +V ++ ATDAD + + + D + F + +G + Sbjct: 1258 SGKKSDYVIPISDADQVGLTVGKLEATDAD---GDDLWWNIFSGD-SDSVFDVRQDTGQL 1313 Query: 640 RTNKALDRESVATHDLKA-VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698 K + E + +L+ +++ G +TVI+ + I+ P F ++ +SE Sbjct: 1314 LLAKKV--ELLKRGELRLNISVTDGQDVDHTTVIIQVS-RQISQR-PAFSANRYDTLVSE 1369 Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758 +GT I ++A + G +V YS+ DD + + R ++ M LDYE Sbjct: 1370 RVAVGTQIHTLKATGENLGTKPLV-YSLFSIDDI-AMEDKIRVEPSSGNVIVMEPLDYE- 1426 Query: 759 PRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQI-IFNNYKDCFPVGPFGRVP 817 + V++ + + ++ + VTD NDNAP + F + D V Sbjct: 1427 VASQIRAVVQVQQANMKSFSKLILEVTDENDNAPYFVEHTAWAFVDENDSVD-DVLATVT 1485 Query: 818 AYDADVTDK--LQYRILSGNNANLILLNETTGSMTLS 852 A+D D D + Y I+SGN +L ++ +G + L+ Sbjct: 1486 AFDRDQDDNGIITYSIVSGNEESLFKIDSHSGEVRLA 1522 Score = 167 bits (405), Expect = 5e-39 Identities = 174/769 (22%), Positives = 318/769 (41%), Gaps = 50/769 (6%) Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 R + +T+ +++ID ND P F Y+ S+ E + + + + ATD D N I Sbjct: 2486 RRRAFSTLTLSVIDINDKPPFFVLPFYSTSIPE--TAKEGDTVLMVSATDED--ENDTIE 2541 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y+++ G FS+ G +++ K L+++ + L I+A D +P TT + IN+ Sbjct: 2542 YSLLDGGESQFFSVHPRQGTITVSKKLEHKAGVTLSLTIKATDSANPPHHATTTVEINVA 2601 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 + PRF S + V E+ IG + VQ + + E+ +T+ + LP Sbjct: 2602 SESVRVPRFSNSHYLFFVPEDADIGDVVGSVQQMETEID---EVRFTIVPGSEVSDSLLP 2658 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 +++ +G + LDRE + ++++ + A G T T Sbjct: 2659 FSVERSTGKIIVKSSLDRERRKQWKMTIRADAAGGVHAITTVTLDILDVNDNAPA---FH 2715 Query: 369 GQYE-VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 G Y+ + ++ED GT V +A D D+ + N F + + G +TVA Sbjct: 2716 GDYDKLTISEDATVGTSVTIFSAMDRDDSPSGRIRFSLVNKDPHFEMNGDS--GWLTVAA 2773 Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 PLD + + Y L ATD GG + I++ D N+ P FE + + P Sbjct: 2774 PLDRETQDLYQLIARATDEGGFNTDLSFTISVNDVNDSPPKFEKDEFDVDLL--LPSNAL 2831 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 +L D D+ N + SE + E V D + + + I NK Y Sbjct: 2832 ILHFDIKDEDLAPNNH-SLLFISEGNEEGVFWIDSENNLLLKRPEIVENK-------KEY 2883 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 L + A DG T V+I + D + T + E + GT V G + Sbjct: 2884 SLKIIAFDG---VFEAKTLVKIHLKSKEDVKTRCPDVEKTVILPESSKKGTVV--FGESS 2938 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA--LDRESVATHDLKAVAIDGGTP 665 L ++L ++ E +FV++ +G+I+ + +D E +L + I G Sbjct: 2939 L---LGPNTTFKL-IEEGAENAFVMNFRNGIIKVKEVGQIDYEKTQEFELIRLTIQG--K 2992 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT----IGEIRAHDPDEGPNAV 721 + + +KIE++ND+PP + + I EN P + I A D D Sbjct: 2993 DELCKERITVKIENLNDNPPKIKEKSVYVSIEENLPTSQDSRQYLTRIAAEDADSDD--- 3049 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781 +H+ + D + +F ++ G + + LD ES + L A+ + + Sbjct: 3050 IHFRLL-DDFNKTFEIDEFSG----VVTVLKPLDSESV-SSFNLTAIASDGNFEDKAIIV 3103 Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLIL 841 + V D NDNAP + + R+ A+ D + ++Y + + ++ + Sbjct: 3104 VTVIDKNDNAPTFEKSTYSMKVMESEAVGYELARLQAFGGDTNETIEYSLKASDHNKFVS 3163 Query: 842 LNETTGSMTLSPQLN-TNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889 LN G +TL+ L+ + L ++ G+ ++++ Q+ + ++ E Sbjct: 3164 LNAQNGVLTLAQPLDFETISTLRLTVIAKDSGIPPLESVAQVEISVMDE 3212 Score = 145 bits (352), Expect = 1e-32 Identities = 191/779 (24%), Positives = 329/779 (42%), Gaps = 78/779 (10%) Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI----SVTDNPVIAKIK-ATDADVG 182 D TA I II N + P F ++ Y +V E++ SV N + + A+D D G Sbjct: 1643 DGQQDTAKIVAKIIRTNQHSPVFRKQVYRGTVRENMEPGSSVLSNRHLPLVLLASDEDSG 1702 Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 +N + Y ++ + F++D SG V K D+E+++ + ++A D G P R + Sbjct: 1703 SNGLVGYRMLSKADEEMFTVDQYSGAVRTNKAFDFEKIKEHSFYVQAFDMGQPPRQSLMP 1762 Query: 243 LL--INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 L + I D ND P+F S + + ++V Q D + + L Y + D Sbjct: 1763 ALVVVTISDENDETPKF-ASQSLDVIMLLPTASQAVVGGQMSDDADSIGT-LRYYIKDS- 1819 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDPPRSATATXXXXXXXX 359 P ++D ++G V + K Y + V TDG ++ Sbjct: 1820 -----SSPFSVDSKTGIVSVKDFKAFTNEKKHYNVEVFVTDGNQ--STSYTMKVTTTSTA 1872 Query: 360 XXXXXXFMPGQYEVELAEDE--PPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ 417 F +Y + E+ PGT ++ + T + ++H+ I N F I Sbjct: 1873 ENSKFKFTRQEYRASIVENSTLTPGTVILPVATTG---EKQVHFTIV--NPHEAFFI--H 1925 Query: 418 NGRGLIT---VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPY 474 +G G+I+ +A + R V+ + + A+V I++ + N+ AP F PY Sbjct: 1926 HGTGVISATGIAVDCELSPVIRLVVEAKTHEKNPQIAKALVLIDVQNVNDEAPKFIGTPY 1985 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 + +V + IGT +L D D G +A I+ SN+ + + V A Sbjct: 1986 SITV-GPSEIGTVILEPKVIDKDEGDHATIS-------SNDMPQYF--KLVGGKVVLAKK 2035 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 + D++ + L + + V + + V I VVD PVF Q +YTA I +++ Sbjct: 2036 LPAIEDQDLKFSFKL-IAKDNSSVHQVEE--PVVIRVVD--KARPVFSQSMYTAVISKES 2090 Query: 595 LVGTS--VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652 ++ V + + G I Y + K F ID +G +R K L+ A Sbjct: 2091 TKKSTVLVHVLARSSLQAKSKGLIGYRIIDK---ANLFSIDYVTGEVRL-KNLNGLDAAE 2146 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDIND-SPPVFESDCLTFYISENSPIGTTIGEIRA 711 + + A + P +S V I ++ + P F+ + + E++ IG I I + Sbjct: 2147 YVFEVEAREVTLPKMASRAQVKIVVKSKSAVQKPTFDKQKYSVTVPESASIGQRIITINS 2206 Query: 712 HDPDEGPNAVVHYSIKG-GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770 PD PN ++ Y + G DD F +++ G E+ LDYE +K LVI + Sbjct: 2207 STPD--PNDILQYKLSGTNDDQPMFEIDSETG----EVSVNRHLDYEKVQKYKMLVIATS 2260 Query: 771 SPPLW-NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRV-PAYDADVT---- 824 S ++ + +++ DVNDN PV + + D G F + A D D T Sbjct: 2261 SAKQQSSEADLIVMIEDVNDNMPVFIRPE-VKAEVSDAAISGQFITIMSATDMDTTSSLD 2319 Query: 825 ---DKLQYRILSGNNANLILLNETTGSMTLSPQL-------NTNVPKLATMEVSVTDGV 873 KL Y+I+ G+ L ++ +TG ++L+ ++ + PK + VSVTDG+ Sbjct: 2320 DPNQKLLYKIVDGDE-TLFNISPSTGEVSLARRIEQEDLTSESEDPK-KVVNVSVTDGM 2376 Score = 145 bits (351), Expect = 2e-32 Identities = 187/769 (24%), Positives = 328/769 (42%), Gaps = 77/769 (10%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLT-------LKATDQDIGKNAEVEYTIELV 65 ++ N HSPVF Q Y +VRE G++VL+ L A+D+D G N V Y + L Sbjct: 1655 IIRTNQHSPVFRKQVYRGTVRENMEPGSSVLSNRHLPLVLLASDEDSGSNGLVGYRM-LS 1713 Query: 66 TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125 AD +++F +D SGA+ T + D EK+ ++ V+A D P Sbjct: 1714 KAD------------------EEMFTVDQYSGAVRTNKAFDFEKIKEHSFYVQAFDMGQP 1755 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 L A + V I D+ND P+F+ ++ V + + V+ + DAD + Sbjct: 1756 PRQSL-MPALVVVTISDENDETPKFASQSLDVIM--LLPTASQAVVGGQMSDDAD--SIG 1810 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDY-EQVRSYRLVIRAQDGGSPSRSNTTQLL 244 +RY I ++ FS+DS +G VS+ + + + Y + + DG ++S + + Sbjct: 1811 TLRYYI--KDSSSPFSVDSKTGIVSVKDFKAFTNEKKHYNVEVFVTDG---NQSTSYTMK 1865 Query: 245 INIRDVNDNAP-RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 + +N+ +F ++ S+ EN + V + E ++ +T+ Sbjct: 1866 VTTTSTAENSKFKFTRQEYRASIVENSTLTPGTVILPVATTGE---KQVHFTIV------ 1916 Query: 304 NVDLPITIDPRSGWVYTSG-QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 N I +G + +G +D E +L+V A P+ A A Sbjct: 1917 NPHEAFFIHHGTGVISATGIAVDCELSPVIRLVVEAKTHEKNPQIAKALVLIDVQNVNDE 1976 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422 F+ Y + + E GT ++ D DE + H I+ + F + G+ + Sbjct: 1977 APKFIGTPYSITVGPSE-IGTVILEPKVIDKDEGD--HATISSNDMPQYFKLV--GGKVV 2031 Query: 423 ITVAQPLDFKQERRYVLTVSATD-SGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 + P Q+ ++ + A D S V I + D PVF + YTA + ++ Sbjct: 2032 LAKKLPAIEDQDLKFSFKLIAKDNSSVHQVEEPVVIRVVD--KARPVFSQSMYTAVISKE 2089 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 + +TVLV S + A+ + I ++A F I+ TG + K L+ Sbjct: 2090 STKKSTVLVHVLARS--SLQAKSKGLIGYRIIDKA-----NLFSIDYVTGEVRL-KNLNG 2141 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVND-NEPVFKQQLYTANIMEDALVGTSV 600 + Y+ V AR+ +P ++ V+I V + +P F +Q Y+ + E A +G + Sbjct: 2142 LDAAEYVFEVEAREVTLPKMASRAQVKIVVKSKSAVQKPTFDKQKYSVTVPESASIGQRI 2201 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 + ++ D N + Y+L + ++ F ID +G + N+ LD E V + + +A Sbjct: 2202 ITINSSTPDP--NDILQYKLSGTNDDQPMFEIDSETGEVSVNRHLDYEKVQKYKMLVIA- 2258 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD----- 715 QSS + + IED+ND+ PVF + +S+ + G I + A D D Sbjct: 2259 TSSAKQQSSEADLIVMIEDVNDNMPVFIRPEVKAEVSDAAISGQFITIMSATDMDTTSSL 2318 Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGS-DKAELVTMVDLDYES--PRK 761 + PN + Y I GD++ F++ G A + DL ES P+K Sbjct: 2319 DDPNQKLLYKIVDGDET-LFNISPSTGEVSLARRIEQEDLTSESEDPKK 2366 Score = 140 bits (339), Expect = 5e-31 Identities = 125/475 (26%), Positives = 206/475 (43%), Gaps = 25/475 (5%) Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD-R 326 E PIG + R + + L + D + N+ LP TI +SG + S +L Sbjct: 391 EMAPIGRVLARFNNCTLENPDDVSLM-RFSISDPSSNISLPFTISSKSGVLRVSSKLSIS 449 Query: 327 ETQAKYQLLVT--ATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 E K+++ V+ G R +M Q + L + PG Sbjct: 450 ERVYKFKVAVSLHGIQGKKDERDVYVEIVDSNNHSPVWSAKWMR-QAPIPLGK---PGDV 505 Query: 385 VVTLTATDADE-DN-RLHYEITG-------GNTRG--RFSITSQNGRGLITV-AQPLDFK 432 ++ + ATD DE DN R+ Y+I NT + +++ ++TV A L Sbjct: 506 LLKVDATDQDEGDNGRVVYKINSEIPFEINANTGEITLIEVPTKSNNWMVTVWAIDLGLP 565 Query: 433 QERRYVLTVSATDSGGRSDTAMVQINITDANN-YAPVFENAPYTASVFEDAPIGTTVLVV 491 R L + +G + + I ++ N ++PVF + P V EDAPIGT V + Sbjct: 566 LSRMSALNLMFYKNGTKVPAKPKPVIIQESENKHSPVFSSFPEVVEVTEDAPIGTVVAKL 625 Query: 492 SATDSDVGINAQITYSLS--SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 ++D D G N I Y + S S+E ++ +Q I + T + +++ + + Sbjct: 626 QSSDEDAGYNGLIRYVIQDISGSSHEILSVDEQSGEIT--VASDLTLLMKEKQKVVEIQV 683 Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 V+A D G P S T +++ + DVN++ P F + Y I E G + + A D D Sbjct: 684 KVSAVDAGTPVKSATRTMKLRIKDVNNHSPHFDEPSYYLAISESEKPGKDIFKATANDFD 743 Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669 G NG+I + L E I+P +G+I+ LDRE H +A D G P + + Sbjct: 744 GGNNGKIKFSLGNNGAESSVISIEPKTGIIKLLNPLDREEQDVHYFSIIASDDGDPARIT 803 Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 + I ++D+ND+ P S I E+ P G + + A D D G N+ + + Sbjct: 804 VTNLTITVDDVNDNAPRCVSQVAKARIPEDLPHGAFVACLAAFDEDVGLNSKLKF 858 Score = 128 bits (308), Expect = 3e-27 Identities = 211/919 (22%), Positives = 377/919 (41%), Gaps = 85/919 (9%) Query: 2 SVPFCIHQQINVLDCNDHSPVF-EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEV-- 58 S PF + + ++ D E + Y V + +T T+K T +N++ Sbjct: 1820 SSPFSVDSKTGIVSVKDFKAFTNEKKHYNVEVFVTDGNQSTSYTMKVTTTSTAENSKFKF 1879 Query: 59 ---EYTIELVTADTLNPED-----AXXXXXXXXXXV---QDVFRIDGRSGAL-LTRASLD 106 EY +V TL P A + + F I +G + T ++D Sbjct: 1880 TRQEYRASIVENSTLTPGTVILPVATTGEKQVHFTIVNPHEAFFIHHGTGVISATGIAVD 1939 Query: 107 REKVARYTVLVKA-TDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISV 165 E ++V+A T + +P + A + +++ + ND P+F Y+++V Sbjct: 1940 CELSPVIRLVVEAKTHEKNPQIAK----ALVLIDVQNVNDEAPKFIGTPYSITVGPSEIG 1995 Query: 166 TDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTL----DYEQVR 221 T VI + K D D G +A I N Q+ + G V L K L D + Sbjct: 1996 T---VILEPKVIDKDEGD-----HATISSNDMPQY-FKLVGGKVVLAKKLPAIEDQDLKF 2046 Query: 222 SYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS-ENVPIGYSIVRVQ 280 S++L+ A+D S + + IR V+ P F S++ +S E+ +V V Sbjct: 2047 SFKLI--AKDNSSVHQVEEP---VVIRVVDKARPVFSQSMYTAVISKESTKKSTVLVHVL 2101 Query: 281 AYDADEGVNAELT-YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTAT 339 A + + + L Y + DK N+ +ID +G V L+ A+Y V A Sbjct: 2102 ARSSLQAKSKGLIGYRIIDK---ANL---FSIDYVTGEVRLKN-LNGLDAAEYVFEVEAR 2154 Query: 340 DGGDPPRSATATXXXXXXXXXXXXX-XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR 398 + P ++ A F +Y V + E G ++T+ ++ D ++ Sbjct: 2155 EVTLPKMASRAQVKIVVKSKSAVQKPTFDKQKYSVTVPESASIGQRIITINSSTPDPNDI 2214 Query: 399 LHYEITGGNT-RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR-SDTAMVQ 456 L Y+++G N + F I S+ G ++V + LD+++ ++Y + V AT S + S A + Sbjct: 2215 LQYKLSGTNDDQPMFEIDSETGE--VSVNRHLDYEKVQKYKMLVIATSSAKQQSSEADLI 2272 Query: 457 INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA 516 + I D N+ PVF A V + A G + ++SATD D + + ++ + Sbjct: 2273 VMIEDVNDNMPVFIRPEVKAEVSDAAISGQFITIMSATDMDTTSSLD---DPNQKLLYKI 2329 Query: 517 VAHHDQQFVINPQTGAITTNKLLDRETMSG------YLLTVTARDGGVPSLSDTTDVEIS 570 V + F I+P TG ++ + +++E ++ ++ V+ DG + + V I Sbjct: 2330 VDGDETLFNISPSTGEVSLARRIEQEDLTSESEDPKKVVNVSVTDGMFTAYAKLV-VGIL 2388 Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG----LNGRIHYELDPKDRE 626 P F+Q Y A +E+ +V S A + G Y ++ Sbjct: 2389 RSGKMQPPPKFEQSHYVATALENTIVNKSALLTVAVKGGIPPLRYSLGPAAYSNSSSSKD 2448 Query: 627 EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686 ID +G I ++ L+ + + + V D ST+ + + DIND PP Sbjct: 2449 SWPVAIDKKTGRIHVSRVLNYHNDKLYQIPLVVEDVTRRRAFSTLT--LSVIDINDKPPF 2506 Query: 687 FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746 F + I E + G T+ + A D DE N + YS+ G +S FS+ RQG+ Sbjct: 2507 FVLPFYSTSIPETAKEGDTVLMVSATDEDE--NDTIEYSLLDGGESQFFSVHPRQGT--- 2561 Query: 747 ELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN 803 + L++++ L I+A A+PP VEI V + P + +F Sbjct: 2562 -ITVSKKLEHKA-GVTLSLTIKATDSANPPHHATTTVEINVASESVRVPRFSNSHYLFFV 2619 Query: 804 YKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILL----NETTGSMTLSPQLNTNV 859 +D G V + ++ D++++ I+ G+ + LL +TG + + L+ Sbjct: 2620 PEDADIGDVVGSVQQMETEI-DEVRFTIVPGSEVSDSLLPFSVERSTGKIIVKSSLDRER 2678 Query: 860 PK--LATMEVSVTDGVNEI 876 K T+ GV+ I Sbjct: 2679 RKQWKMTIRADAAGGVHAI 2697 Score = 98.7 bits (235), Expect = 2e-18 Identities = 79/278 (28%), Positives = 127/278 (45%), Gaps = 18/278 (6%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I+V+D ND++P FE ++Y V+E + G VLT+KA D D V Y +EL+ Sbjct: 3206 EISVMDENDNAPKFEKEKYTGKVKENSKVGEKVLTVKAVDADSEHFGAVSYELELIA--- 3262 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 D V F I+ +G +L +D EK +Y + + A D P Sbjct: 3263 ----DKASDDSLPTTSVTPPFSINA-NGDVLINQPIDYEKTKKYNLKLIAKDGGRP---P 3314 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L S A + +++ D+NDN P F + T V E S+ + K +D D N A Sbjct: 3315 LVSEALLDIHVGDENDNAPVFDDCNMTAVVQEGESIGHK--VLKFSISDLDGPTNGAPFT 3372 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I G+ F ++ ++ K L++ Y L + A+D + +S L + IR Sbjct: 3373 VEIQGDGAKSFKVND-KLELLTAKKLEHRNKDKYLLTVIAKD--TKGKSTDCPLTVFIRQ 3429 Query: 250 VNDNAPRFYTSLFQESVSEN-VPIGYSIVRVQAYDADE 286 + +AP Q + +N +P G I R++A+D DE Sbjct: 3430 ASRHAPTMKPMKIQVNTLQNELPEGV-IGRLKAFDEDE 3466 Score = 71.3 bits (167), Expect = 4e-10 Identities = 45/132 (34%), Positives = 76/132 (57%), Gaps = 10/132 (7%) Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQF--SEKTYTVSVDED 162 L+RE Y +LVKAT + +S+ L +TA IH+ +ID ND P F E+ Y +D+D Sbjct: 109 LNRELKDFYDILVKATCKRRDLSN-LETTARIHLRVIDKNDASPLFLVDEQGYEAVIDDD 167 Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222 + +++A+DAD+G NSAI ++++ N F ++ +SG ++TL + + Sbjct: 168 TEPFST--VLRVEASDADIGINSAIYFSLV--NRSHDFLVEPVSG---WIRTLRHLKPGK 220 Query: 223 YRLVIRAQDGGS 234 Y L ++A+D S Sbjct: 221 YSLKVKAEDRAS 232 Score = 58.4 bits (135), Expect = 3e-06 Identities = 37/111 (33%), Positives = 62/111 (55%), Gaps = 7/111 (6%) Query: 539 LDRETMSGY--LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF--KQQLYTANIMEDA 594 L+RE Y L+ T + + +L T + + V+D ND P+F +Q Y A I +D Sbjct: 109 LNRELKDFYDILVKATCKRRDLSNLETTARIHLRVIDKNDASPLFLVDEQGYEAVIDDDT 168 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645 ++V +V A+DAD+G+N I++ L + + F+++P SG IRT + L Sbjct: 169 EPFSTVLRVEASDADIGINSAIYFSLVNRSHD---FLVEPVSGWIRTLRHL 216 Score = 53.2 bits (122), Expect = 1e-04 Identities = 70/303 (23%), Positives = 111/303 (36%), Gaps = 38/303 (12%) Query: 1310 CPEKRSRCSSAPCYNGAEC--SDLWDTYICDCKEGHTGKDC----ADSTGP-----PWRF 1358 C + ++CS +PC C S T+ C C G G C + G Sbjct: 3714 CEIETNQCSKSPCEQWQMCIPSVFNSTFECVCPLGMEGDRCLVPSCKNDGKCLEEAELSV 3773 Query: 1359 GGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVM---------SIQLKSGLLHYSYNGE 1409 GGDG + L I+ + ++T + +M ++L +G Y ++ Sbjct: 3774 GGDGYFEIS-LSNEIESRMELEIELKTTSPNGIIMWSRGRHDYHMLRLVNGSAQYHWDAG 3832 Query: 1410 T---MYLPMATLSDGAWHRIEIKWLGTDISVTV-DYGLRTVLMPMLANKIQGQYIGKILI 1465 T + + DG WHRI I +TV D GL P+ + + + L+ Sbjct: 3833 TGTGIVTSKTLIVDGQWHRITISRRQRRTRMTVDDDGLEEAFSPVGSTVVNLHRYSQKLV 3892 Query: 1466 GGLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRPTVR-ENVRDGCQ--SRADCMLSIC 1522 G G L + GC + + I + L R ++ V+ GC + + C C Sbjct: 3893 LGAKVENGQLTDGI---SGCFRTISIDGIKVLKTRQGMKLFGVQPGCSALTSSPCNDLPC 3949 Query: 1523 PPYSKCVTSWDSS-TCTCEAGRVGPQC---VSACELGPCGAA-RCVPDQTPKGYSCACEP 1577 CV+ S C C + G C + C PC +C+P Y C C Sbjct: 3950 KHGGTCVSHGKSQFVCQCTSRYSGDTCEIDLEPCSSTPCPTGIQCIPFY--NDYLCKCPN 4007 Query: 1578 GYT 1580 G+T Sbjct: 4008 GFT 4010 Score = 48.4 bits (110), Expect = 0.003 Identities = 42/134 (31%), Positives = 66/134 (49%), Gaps = 18/134 (13%) Query: 428 PLDFKQERRYVLTVSAT----DSGGRSDTAMVQINITDANNYAPVF--ENAPYTASVFED 481 PL+ + + Y + V AT D TA + + + D N+ +P+F + Y A + +D Sbjct: 108 PLNRELKDFYDILVKATCKRRDLSNLETTARIHLRVIDKNDASPLFLVDEQGYEAVIDDD 167 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 +TVL V A+D+D+GIN+ I +SL + HD F++ P +G I T + L Sbjct: 168 TEPFSTVLRVEASDADIGINSAIYFSLVNR-------SHD--FLVEPVSGWIRTLRHL-- 216 Query: 542 ETMSGYLLTVTARD 555 Y L V A D Sbjct: 217 -KPGKYSLKVKAED 229 Score = 42.3 bits (95), Expect = 0.19 Identities = 46/207 (22%), Positives = 89/207 (42%), Gaps = 24/207 (11%) Query: 149 QFSEKTYTVSVDEDI---SVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205 +F+ Y +SV+E+ + KI + AN R A I G F + Sbjct: 32 EFTAPLYNLSVEENSIGSKYARSENATKIGVPLPEKDANCKFRVAEIAGEKSSLFKAHAR 91 Query: 206 S-GDVSLVKT-------LDYEQVRSYRLVIRA--QDGGSPSRSNTTQLLINIRDVNDNAP 255 GD ++ L+ E Y ++++A + + T ++ + + D ND +P Sbjct: 92 QVGDFVFLRIRYKGDNPLNRELKDFYDILVKATCKRRDLSNLETTARIHLRVIDKNDASP 151 Query: 256 RFYTSL--FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313 F ++ + ++ +++RV+A DAD G+N+ + +++ ++ + ++P Sbjct: 152 LFLVDEQGYEAVIDDDTEPFSTVLRVEASDADIGINSAIYFSLVNRSH------DFLVEP 205 Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATD 340 SGW+ T L KY L V A D Sbjct: 206 VSGWIRTLRHL---KPGKYSLKVKAED 229 Score = 41.1 bits (92), Expect = 0.43 Identities = 20/54 (37%), Positives = 35/54 (64%), Gaps = 2/54 (3%) Query: 11 INVLDCNDHSPVF--EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 + V+D ND SP+F + Q YEA + + +TVL ++A+D DIG N+ + +++ Sbjct: 141 LRVIDKNDASPLFLVDEQGYEAVIDDDTEPFSTVLRVEASDADIGINSAIYFSL 194 >UniRef50_A7S5P0 Cluster: Predicted protein; n=3; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 4639 Score = 309 bits (759), Expect = 6e-82 Identities = 243/795 (30%), Positives = 372/795 (46%), Gaps = 64/795 (8%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +F I+G + + LDRE A++ + + T+ + + + VN++D ND P Sbjct: 858 MFSING-TNLRVGSTPLDRETAAQHILDISLTEGGT-----IKGFVKVTVNVLDINDETP 911 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 F ++ VSV+E + V + ATD D GANSA+ Y+I GN + FSI++ +G Sbjct: 912 LFQSPSFNVSVNEIERL--GTVFLTVSATDGDAGANSALTYSIAVGNEEGFFSINNKTGA 969 Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268 +S+ K LD E Y L + AQDGG P ++TT + I + D NDN P ++ Q S+SE Sbjct: 970 ISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSE 1029 Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328 I + V A D D G N L Y++ + G+ + D SG + +G L Sbjct: 1030 TAEIDTPVATVIASDKDIGANGRLMYSI-ESGAHGHFRIK---DSSSGAISLAGMLSYNQ 1085 Query: 329 QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388 + Y ++V TDGG P + A Y+V + E E V+ L Sbjct: 1086 RNNYIVVVNVTDGGSPALKSRAMVVIDVTPKPRNLT------YDVSVLEGE-ANVQVMDL 1138 Query: 389 TATDADEDNRLHYEITGGNTR---GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445 ++ H+ ++GGN S+ S NG L + PLD + +++L +S T+ Sbjct: 1139 KPAES------HFNVSGGNFTFFDSSGSMFSINGTNLRVGSTPLDRETAAQHILDISLTE 1192 Query: 446 SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505 G V +N+ D N+ P+F++ + SV E +GT L VSATD D G N+ +T Sbjct: 1193 GGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALT 1252 Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTT 565 YS+ A + + F IN +TGAI+ K LDRET Y LTV A+DGG P L+ TT Sbjct: 1253 YSI-------AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTT 1305 Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625 V I V D NDN PV + + ++ E A + T V+ V A+D D+G NGR+ Y ++ Sbjct: 1306 AVAIQVGDANDNPPVIQDAVIRVSLSETAEIDTPVATVIASDKDIGANGRLMYSIE--SG 1363 Query: 626 EEGSFVI-DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP 684 G F I D +SG I L + + DGG+P S +V I D+ P Sbjct: 1364 AHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVI---DVKPKP 1420 Query: 685 PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS---NSFSLETRQ 741 LT+ +S GE D P A H+++ GG+ + +S S+ + Sbjct: 1421 -----RNLTYDVS------VLEGEANVQVMDLKP-AESHFNVSGGNFTFFDSSGSMFSIN 1468 Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMK--DFQI 799 G++ V LD E+ + + + V+V + V D+ND P+ + F + Sbjct: 1469 GTNLR--VGSTPLDRETAAQHILDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNV 1526 Query: 800 IFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNT 857 N + V F V A D D L Y I +GN +N TG+++++ QL+ Sbjct: 1527 SVNEIERLGTV--FLTVSATDGDAGANSALTYSIAAGNEEGFFSINNKTGAISVAKQLDR 1584 Query: 858 NVPKLATMEVSVTDG 872 T+ V DG Sbjct: 1585 ETRDQYTLTVMAQDG 1599 Score = 301 bits (740), Expect = 1e-79 Identities = 265/872 (30%), Positives = 403/872 (46%), Gaps = 78/872 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NVLD ND +P+F+ + SV E GT LT+ ATD D G N+ + Y+I + + Sbjct: 901 VNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAVGNEEGF 960 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F I+ ++GA+ LDRE +YT+ V A D P L Sbjct: 961 -------------------FSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPP---L 998 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +ST + + + D NDN P + VS+ E + D PV A + A+D D+GAN + Y+ Sbjct: 999 NSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEI-DTPV-ATVIASDKDIGANGRLMYS 1056 Query: 191 IIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I G F I DS SG +SL L Y Q +Y +V+ DGGSP+ + ++I++ Sbjct: 1057 IESG-AHGHFRIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVTP 1115 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 PR T + SV E G + V+V E T D +G++ Sbjct: 1116 ----KPRNLT--YDVSVLE----GEANVQVMDLKPAESHFNVSGGNFTFFDSSGSMFSIN 1165 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 + R G S LDRET A++ L ++ T+GG T F Sbjct: 1166 GTNLRVG----STPLDRETAAQHILDISLTEGGTIKGFVKVTVNVLDINDETPL--FQSP 1219 Query: 370 QYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 + V + E E GT +T++ATD D ++ L Y I GN G FSI N G I+VA+ Sbjct: 1220 SFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAAGNEEGFFSIN--NKTGAISVAK 1277 Query: 428 PLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 LD + +Y LTV A D G + T V I + DAN+ PV ++A S+ E A I Sbjct: 1278 QLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSETAEID 1337 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 T V V A+D D+G N ++ YS+ E+ AH Q + + +GAI+ +L + Sbjct: 1338 TPVATVIASDKDIGANGRLMYSI------ESGAHGHFQ-IKDSSSGAISLAGMLSYNQRN 1390 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 Y++ V DGG P+L V V+DV +P + Y +++E V + Sbjct: 1391 NYIVVVNVTDGGSPALKSRAMV---VIDV---KPKPRNLTYDVSVLEGE-ANVQVMDLKP 1443 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 ++ ++G D GS + + + LDRE+ A H L +GGT Sbjct: 1444 AESHFNVSGGNFTFFD----SSGSMFSINGTNLRVGSTPLDRETAAQHILDISLTEGGTI 1499 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 V V + + DIND P+F+S ++E +GT + A D D G N+ + YS Sbjct: 1500 --KGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYS 1557 Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEI 782 I G++ FS+ + G+ + LD E+ R +Y L + A PPL + V I Sbjct: 1558 IAAGNEEGFFSINNKTGA----ISVAKQLDRET-RDQYTLTVMAQDGGEPPLNSTTAVAI 1612 Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLI 840 V D NDN PV++D I + + P V A D D+ +L Y I SG + + Sbjct: 1613 QVGDANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESGAHGHFQ 1672 Query: 841 LLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 + + ++G+++L+ L+ N + V+VTDG Sbjct: 1673 IKDSSSGAISLAGMLSYNQRNNYIVVVNVTDG 1704 Score = 301 bits (739), Expect = 2e-79 Identities = 242/795 (30%), Positives = 368/795 (46%), Gaps = 64/795 (8%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +F I+G + + LDRE A++ + + T+ + + + VN++D ND P Sbjct: 3496 MFSING-TNLRVGSTPLDRETAAQHILDISLTEGGT-----IKGFVKVTVNVLDINDETP 3549 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 F ++ VSV+E + V + ATD D GANSA+ Y+I GN + FSI++ +G Sbjct: 3550 LFQSPSFNVSVNEIERL--GTVFLTVSATDGDAGANSALTYSIAVGNEEGFFSINNKTGA 3607 Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268 +S+ K LD E Y L + AQDGG P ++TT + I + D NDN P ++ Q S+SE Sbjct: 3608 ISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSE 3667 Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328 I + V A D D G N L Y++ + G+ + D SG + +G L Sbjct: 3668 TAEIDTPVATVIASDKDIGANGRLMYSIESGAH-GHFRIK---DSSSGAISLAGMLSYNQ 3723 Query: 329 QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388 + Y ++V TDGG P + A Y+V + E E V+ L Sbjct: 3724 RNNYIVVVNVTDGGSPALKSRAMVVIDVTPKPRNLT------YDVSVLEGEA-NVQVMDL 3776 Query: 389 TATDADEDNRLHYEITGGNT---RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445 + H+ ++GGN S+ S NG L + PLD + ++VL +S T+ Sbjct: 3777 KPVVS------HFNVSGGNFTFFNSSGSMFSINGNNLSVGSTPLDRETAAQHVLDISLTE 3830 Query: 446 SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505 G V +N+ D N+ P+F++ + SV E +GT L VSATD D G N+ +T Sbjct: 3831 GGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALT 3890 Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTT 565 YS+ A + + F IN +TGAI+ K LDRET Y LTV A+DGG P L+ TT Sbjct: 3891 YSI-------AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTT 3943 Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625 V I V D NDN PV + + ++ E A + T V+ V A+D D+G NGR+ Y ++ Sbjct: 3944 AVAIQVGDANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIE--SG 4001 Query: 626 EEGSFVI-DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP 684 G F I D +SG I L + + DGG+P S +V I D+ P Sbjct: 4002 AHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVI---DVTPKP 4058 Query: 685 PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS---NSFSLETRQ 741 LT+ +S GE D P A H++ GG + +S S+ + Sbjct: 4059 RN-----LTYDVS------VLEGEANVQVMDLKP-AESHFNASGGTFAFFGSSGSMFSIN 4106 Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKD--FQI 799 G++ V LD E+ + + + +V + V D+ND P + F + Sbjct: 4107 GTNLR--VGSTPLDRETAEEHVLDISLTEGGIVKGLFKVTVNVLDINDETPSFQSPSFNV 4164 Query: 800 IFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNT 857 N + V F V A D+D L Y I +GN + +N T +++++ QL+ Sbjct: 4165 SVNEIERLGTV--FLTVSATDSDAGANSALTYSIAAGNEEGVFSINNKTAAISVAKQLDR 4222 Query: 858 NVPKLATMEVSVTDG 872 L + V DG Sbjct: 4223 ETRDLYMLTVMAQDG 4237 Score = 295 bits (723), Expect = 1e-77 Identities = 211/661 (31%), Positives = 320/661 (48%), Gaps = 42/661 (6%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +F I+G + ++ + LDRE A++ + + T+ + + + VN++D ND P Sbjct: 3799 MFSINGNNLSVGS-TPLDRETAAQHVLDISLTEGGT-----IKGFVKVTVNVLDINDETP 3852 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 F ++ VSV+E + V + ATD D GANSA+ Y+I GN + FSI++ +G Sbjct: 3853 LFQSPSFNVSVNEIERL--GTVFLTVSATDGDAGANSALTYSIAAGNEEGFFSINNKTGA 3910 Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268 +S+ K LD E Y L + AQDGG P ++TT + I + D NDN P ++ + S+SE Sbjct: 3911 ISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSE 3970 Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328 I + V A D D G N L Y++ + G+ + D SG + +G L Sbjct: 3971 TAAIDTPVATVIASDKDIGANGRLMYSIESGAH-GHFQIK---DSSSGAISLAGMLSYNQ 4026 Query: 329 QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388 + Y ++V TDGG P + A Y+V + E E V+ L Sbjct: 4027 RNNYIVVVNVTDGGSPALKSRAMVVIDVTPKPRNLT------YDVSVLEGEA-NVQVMDL 4079 Query: 389 TATDADEDNRLHYEITGGNTR---GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445 ++ H+ +GG S+ S NG L + PLD + +VL +S T+ Sbjct: 4080 KPAES------HFNASGGTFAFFGSSGSMFSINGTNLRVGSTPLDRETAEEHVLDISLTE 4133 Query: 446 SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505 G V +N+ D N+ P F++ + SV E +GT L VSATDSD G N+ +T Sbjct: 4134 GGIVKGLFKVTVNVLDINDETPSFQSPSFNVSVNEIERLGTVFLTVSATDSDAGANSALT 4193 Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTT 565 YS+ A + + F IN +T AI+ K LDRET Y+LTV A+DGG PSL+ T Sbjct: 4194 YSI-------AAGNEEGVFSINNKTAAISVAKQLDRETRDLYMLTVMAQDGGEPSLNRTA 4246 Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625 V I V D NDN PV + + ++ E A + T V+ V A+D D+G NGR+ Y ++ Sbjct: 4247 AVPIQVGDANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIE--SG 4304 Query: 626 EEGSFVI-DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI--ND 682 G F I D +SG I L + + + DGG+ S IV I + N Sbjct: 4305 AHGHFQIKDSSSGAISVAGRLSYKQRNNYSVVVKVTDGGSLALESRAIVLIDVTPTTENR 4364 Query: 683 SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 + PVF S + +++ + + A D D G N VV Y I +D++ F +E G Sbjct: 4365 NAPVFASVQYIGGVYKDTSFDFPVLTVVATDSDTGINGVVEYRI--SEDTDLFYIEPTSG 4422 Query: 743 S 743 + Sbjct: 4423 T 4423 Score = 266 bits (651), Expect = 8e-69 Identities = 251/857 (29%), Positives = 384/857 (44%), Gaps = 94/857 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+ PV + + S+ E A T V T+ A+D+DIG N + Y+IE Sbjct: 3644 IQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGANGRLMYSIE------- 3696 Query: 71 NPEDAXXXXXXXXXXVQDVFRI-DGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 FRI D SGA+ L + Y V+V TD SP Sbjct: 3697 -------------SGAHGHFRIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPA--- 3740 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE---DISVTD-NPVIAKIKATDADVGANS 185 L S A + +++ P+ TY VSV E ++ V D PV++ + G N Sbjct: 3741 LKSRAMVVIDVT------PKPRNLTYDVSVLEGEANVQVMDLKPVVSHFNVS----GGN- 3789 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 + + M FSI+ ++S+ T LD E + L I +GG+ ++ Sbjct: 3790 ---FTFFNSSGSM-FSING--NNLSVGSTPLDRETAAQHVLDISLTEGGTIK--GFVKVT 3841 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 +N+ D+ND P F + F SV+E +G + V A D D G N+ LTY++ GN Sbjct: 3842 VNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIA----AGN 3897 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 + +I+ ++G + + QLDRET+ +Y L V A DGG+PP ++T Sbjct: 3898 EEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPP 3957 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGL 422 V L+E TPV T+ A+D D + RL Y I G G F I + G Sbjct: 3958 VIQDAVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESG-AHGHFQIKDSSS-GA 4015 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFE 480 I++A L + Q Y++ V+ TD G + AMV I++T P N Y SV E Sbjct: 4016 ISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVT------PKPRNLTYDVSVLE 4069 Query: 481 DAPIGTTVLVVSATDSDVGINAQI-TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 V V+ ++ NA T++ + F IN T + L Sbjct: 4070 GE---ANVQVMDLKPAESHFNASGGTFAFFGSSGS--------MFSING-TNLRVGSTPL 4117 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 DRET ++L ++ +GG+ + V ++V+D+ND P F+ + ++ E +GT Sbjct: 4118 DRETAEEHVLDISLTEGGI--VKGLFKVTVNVLDINDETPSFQSPSFNVSVNEIERLGTV 4175 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 V ATD+D G N + Y + EEG F I+ + I K LDRE+ + L +A Sbjct: 4176 FLTVSATDSDAGANSALTYSI-AAGNEEGVFSINNKTAAISVAKQLDRETRDLYMLTVMA 4234 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 DGG P + T V I++ D ND+PPV + + +SE + I T + + A D D G N Sbjct: 4235 QDGGEPSLNRTAAVPIQVGDANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKDIGAN 4294 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP-PLWNDV 778 + YSI+ G + F ++ S + L Y+ R Y +V++ L + Sbjct: 4295 GRLMYSIESGAHGH-FQIKD---SSSGAISVAGRLSYKQ-RNNYSVVVKVTDGGSLALES 4349 Query: 779 RVEILV----TDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRIL 832 R +L+ T N NAPV Q I YKD P V A D+D + ++YRI Sbjct: 4350 RAIVLIDVTPTTENRNAPVFASVQYIGGVYKDTSFDFPVLTVVATDSDTGINGVVEYRI- 4408 Query: 833 SGNNANLILLNETTGSM 849 + +L + T+G++ Sbjct: 4409 -SEDTDLFYIEPTSGTI 4424 Score = 258 bits (633), Expect = 1e-66 Identities = 232/784 (29%), Positives = 351/784 (44%), Gaps = 78/784 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+ PV + + S+ E A T V T+ A+D+DIG N + Y+IE Sbjct: 1006 IQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGANGRLMYSIE------- 1058 Query: 71 NPEDAXXXXXXXXXXVQDVFRI-DGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 FRI D SGA+ L + Y V+V TD SP Sbjct: 1059 -------------SGAHGHFRIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPA--- 1102 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L S A + +++ P+ TY VSV E + N + +K ++ + + Sbjct: 1103 LKSRAMVVIDVT------PKPRNLTYDVSVLEGEA---NVQVMDLKPAESHFNVSGG-NF 1152 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 + M FSI+ + V LD E + L I +GG+ ++ +N+ D Sbjct: 1153 TFFDSSGSM-FSINGTNLRVGSTP-LDRETAAQHILDISLTEGGTIK--GFVKVTVNVLD 1208 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 +ND P F + F SV+E +G + V A D D G N+ LTY++ GN + Sbjct: 1209 INDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIA----AGNEEGFF 1264 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 +I+ ++G + + QLDRET+ +Y L V A DGG+PP ++T Sbjct: 1265 SINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDA 1324 Query: 370 QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 V L+E TPV T+ A+D D + RL Y I G G F I + G I++A Sbjct: 1325 VIRVSLSETAEIDTPVATVIASDKDIGANGRLMYSIESG-AHGHFQIKDSSS-GAISLAG 1382 Query: 428 PLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 L + Q Y++ V+ TD G + AMV I++ P N Y SV E Sbjct: 1383 MLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVK------PKPRNLTYDVSVLE-GEAN 1435 Query: 486 TTVLVVSATDSDVGINA-QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 V+ + +S ++ T+ SS F IN T + LDRET Sbjct: 1436 VQVMDLKPAESHFNVSGGNFTFFDSS----------GSMFSING-TNLRVGSTPLDRETA 1484 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 + ++L ++ +GG ++ V ++V+D+ND P+F+ + ++ E +GT V Sbjct: 1485 AQHILDISLTEGG--TIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVS 1542 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 ATD D G N + Y + EEG F I+ +G I K LDRE+ + L +A DGG Sbjct: 1543 ATDGDAGANSALTYSI-AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGE 1601 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 PP +ST V I++ D ND+PPV + + +SE + I T + + A D D G N + Y Sbjct: 1602 PPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKDIGANGRLMY 1661 Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR---AASPPLWNDVRVE 781 SI+ G + F ++ S L M L Y + R Y +V+ SP L + V Sbjct: 1662 SIESGAHGH-FQIKD-SSSGAISLAGM--LSY-NQRNNYIVVVNVTDGGSPALKSRAMVV 1716 Query: 782 ILVT 785 I VT Sbjct: 1717 IDVT 1720 Score = 254 bits (621), Expect = 3e-65 Identities = 217/681 (31%), Positives = 313/681 (45%), Gaps = 61/681 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NVLD ND +P+F+ + SV E GT LT+ ATD D G N+ + Y+I Sbjct: 3842 VNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-------- 3893 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F I+ ++GA+ LDRE +YT+ V A D P L Sbjct: 3894 -----------AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPP---L 3939 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +ST + + + D NDN P + VS+ E ++ D PV A + A+D D+GAN + Y+ Sbjct: 3940 NSTTAVAIQVGDANDNPPVIQDAVIRVSLSETAAI-DTPV-ATVIASDKDIGANGRLMYS 3997 Query: 191 IIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I G F I DS SG +SL L Y Q +Y +V+ DGGSP+ + ++I++ Sbjct: 3998 IESG-AHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVTP 4056 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 PR T + SV E G + V+V E T +G++ Sbjct: 4057 ----KPRNLT--YDVSVLE----GEANVQVMDLKPAESHFNASGGTFAFFGSSGSMFSIN 4106 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 + R G S LDRET ++ L ++ T+GG T F Sbjct: 4107 GTNLRVG----STPLDRETAEEHVLDISLTEGGIVKGLFKVTVNVLDINDETPS--FQSP 4160 Query: 370 QYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 + V + E E GT +T++ATD+D ++ L Y I GN G FSI N I+VA+ Sbjct: 4161 SFNVSVNEIERLGTVFLTVSATDSDAGANSALTYSIAAGNEEGVFSI--NNKTAAISVAK 4218 Query: 428 PLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 LD + Y+LTV A D G S TA V I + DAN+ PV ++A S+ E A I Sbjct: 4219 QLDRETRDLYMLTVMAQDGGEPSLNRTAAVPIQVGDANDNPPVIQDAVIRVSLSETAAID 4278 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 T V V A+D D+G N ++ YS+ E+ AH Q + + +GAI+ L + + Sbjct: 4279 TPVATVIASDKDIGANGRLMYSI------ESGAHGHFQ-IKDSSSGAISVAGRLSYKQRN 4331 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDV--NDNEPVFKQQLYTANIMEDALVGTSVSQV 603 Y + V DGG +L V I V N N PVF Y + +D V V Sbjct: 4332 NYSVVVKVTDGGSLALESRAIVLIDVTPTTENRNAPVFASVQYIGGVYKDTSFDFPVLTV 4391 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL-DRESVATHDLKAVAIDG 662 ATD+D G+NG + Y + + F I+P SG IRT D++ + A D Sbjct: 4392 VATDSDTGINGVVEYRI---SEDTDLFYIEPTSGTIRTADIFADKDRGLSFSFMVQASDK 4448 Query: 663 GTPPQSSTVIVHIKIEDINDS 683 GTPP+ + HI I + DS Sbjct: 4449 GTPPKKTKENAHITIFLLRDS 4469 Score = 243 bits (595), Expect = 5e-62 Identities = 222/759 (29%), Positives = 340/759 (44%), Gaps = 78/759 (10%) Query: 36 ASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRI-DG 94 A T V T+ A+D+DIG N + Y+IE F+I D Sbjct: 3366 AEIDTPVATVIASDKDIGANGRLMYSIE--------------------SGAHGHFQIKDS 3405 Query: 95 RSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKT 154 SGA+ L + Y V+V TD SP L S A + +++ P+ T Sbjct: 3406 SSGAISLAGMLSYNQRNNYIVVVNVTDGGSPA---LKSRAMVVIDV------KPKPRNLT 3456 Query: 155 YTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT 214 Y VSV E + N + +K ++ + + + M FSI+ + V Sbjct: 3457 YDVSVLEGEA---NVQVMDLKPAESHFNVSGG-NFTFFDSSGSM-FSINGTNLRVGSTP- 3510 Query: 215 LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY 274 LD E + L I +GG+ ++ +N+ D+ND P F + F SV+E +G Sbjct: 3511 LDRETAAQHILDISLTEGGTIK--GFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGT 3568 Query: 275 SIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQL 334 + V A D D G N+ LTY++ GN + +I+ ++G + + QLDRET+ +Y L Sbjct: 3569 VFLTVSATDGDAGANSALTYSIA----VGNEEGFFSINNKTGAISVAKQLDRETRDQYTL 3624 Query: 335 LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394 V A DGG+PP ++T +V L+E TPV T+ A+D D Sbjct: 3625 TVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKD 3684 Query: 395 --EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS-- 450 + RL Y I G G F I + G I++A L + Q Y++ V+ TD G + Sbjct: 3685 IGANGRLMYSIESG-AHGHFRIKDSSS-GAISLAGMLSYNQRNNYIVVVNVTDGGSPALK 3742 Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA-QITYSLS 509 AMV I++T P N Y SV E V+ + S ++ T+ S Sbjct: 3743 SRAMVVIDVT------PKPRNLTYDVSVLE-GEANVQVMDLKPVVSHFNVSGGNFTFFNS 3795 Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569 S F IN ++ + L DRET + ++L ++ +GG ++ V + Sbjct: 3796 S----------GSMFSINGNNLSVGSTPL-DRETAAQHVLDISLTEGG--TIKGFVKVTV 3842 Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629 +V+D+ND P+F+ + ++ E +GT V ATD D G N + Y + EEG Sbjct: 3843 NVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-AAGNEEGF 3901 Query: 630 FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES 689 F I+ +G I K LDRE+ + L +A DGG PP +ST V I++ D ND+PPV + Sbjct: 3902 FSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQD 3961 Query: 690 DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV 749 + +SE + I T + + A D D G N + YSI+ G + F ++ S L Sbjct: 3962 AVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESGAHGH-FQIKD-SSSGAISLA 4019 Query: 750 TMVDLDYESPRKKYELVIR---AASPPLWNDVRVEILVT 785 M L Y + R Y +V+ SP L + V I VT Sbjct: 4020 GM--LSY-NQRNNYIVVVNVTDGGSPALKSRAMVVIDVT 4055 Score = 241 bits (590), Expect = 2e-61 Identities = 223/819 (27%), Positives = 358/819 (43%), Gaps = 68/819 (8%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +F I+G + + LDRE A++ + + T+ + + + VN++D ND P Sbjct: 616 MFSING-TNLRVGSTPLDRETAAQHILDISLTEGGT-----IKGFVKVTVNVLDINDETP 669 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 F ++ VSV+E + V + ATD D GANSA+ Y+I GN + FSI++ +G Sbjct: 670 LFQSPSFNVSVNEIERL--GTVFLTVSATDGDAGANSALTYSIAAGNEEGFFSINNKTGA 727 Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268 +S+ K LD E Y L + AQDGG P ++TT + I + D NDN P ++ + S+SE Sbjct: 728 ISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSE 787 Query: 269 ---NVPIGYSIV---RVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322 NV G S R LTY ++ + NV + S + + G Sbjct: 788 VVVNVTDGGSPALKSRAMVVIDVTPKPRNLTYDVSVLEGEANVQVMDLKPAESHFNVSGG 847 Query: 323 QLDRETQAKYQLLVTATD---GGDPPRSATAT--XXXXXXXXXXXXXXFMPGQYEVELAE 377 + + T+ G P TA F+ V Sbjct: 848 NFTFFDSSGSMFSINGTNLRVGSTPLDRETAAQHILDISLTEGGTIKGFVKVTVNVLDIN 907 Query: 378 DEPP--GTPVVTLTATDADEDNRLHYEIT------GGNTRGRFSITSQNGRGLITV---- 425 DE P +P ++ + + + ++ G N+ +SI N G ++ Sbjct: 908 DETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAVGNEEGFFSINNKT 967 Query: 426 -----AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASV 478 A+ LD + +Y LTV A D G + T V I + DAN+ PV ++A S+ Sbjct: 968 GAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSL 1027 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 E A I T V V A+D D+G N ++ YS+ S H + + +GAI+ + Sbjct: 1028 SETAEIDTPVATVIASDKDIGANGRLMYSIES-------GAHGHFRIKDSSSGAISLAGM 1080 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 L + Y++ V DGG P+L V V+DV P + Y +++E Sbjct: 1081 LSYNQRNNYIVVVNVTDGGSPALKSRAMV---VIDVT---PKPRNLTYDVSVLEGE-ANV 1133 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 V + ++ ++G D GS + + + LDRE+ A H L Sbjct: 1134 QVMDLKPAESHFNVSGGNFTFFD----SSGSMFSINGTNLRVGSTPLDRETAAQHILDIS 1189 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 +GGT V V + + DIND P+F+S ++E +GT + A D D G Sbjct: 1190 LTEGGT--IKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGA 1247 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLW 775 N+ + YSI G++ FS+ + G+ + LD E+ R +Y L + A PPL Sbjct: 1248 NSALTYSIAAGNEEGFFSINNKTGA----ISVAKQLDRET-RDQYTLTVMAQDGGEPPLN 1302 Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILS 833 + V I V D NDN PV++D I + + P V A D D+ +L Y I S Sbjct: 1303 STTAVAIQVGDANDNPPVIQDAVIRVSLSETAEIDTPVATVIASDKDIGANGRLMYSIES 1362 Query: 834 GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 G + + + + ++G+++L+ L+ N + V+VTDG Sbjct: 1363 GAHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDG 1401 Score = 234 bits (573), Expect = 2e-59 Identities = 211/750 (28%), Positives = 329/750 (43%), Gaps = 76/750 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NVLD ND +P+F+ + SV E GT LT+ ATD D G N+ + Y+I Sbjct: 659 VNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-------- 710 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F I+ ++GA+ LDRE +YT+ V A D P L Sbjct: 711 -----------AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEP---PL 756 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDE-DISVTD--NPVIAKIKATDADV---GAN 184 +ST + + + D NDN P + VS+ E ++VTD +P + DV N Sbjct: 757 NSTTAVAIQVGDANDNPPVIQDAVIRVSLSEVVVNVTDGGSPALKSRAMVVIDVTPKPRN 816 Query: 185 SAIRYAIIGG--NTQ-MQFSIDSLSGDVSLVKTLDYEQVRSYRLV--IRAQDGGSP-SRS 238 +++ G N Q M +VS ++ S + + G +P R Sbjct: 817 LTYDVSVLEGEANVQVMDLKPAESHFNVSGGNFTFFDSSGSMFSINGTNLRVGSTPLDRE 876 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQE--SVSENVPIGYS-IVRVQAYDADEGVNAELTYT 295 Q +++I + + + +++ P+ S V + + LT + Sbjct: 877 TAAQHILDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVS 936 Query: 296 MTDKDYTGNVDLPITI-----------DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP 344 TD D N L +I + ++G + + QLDRET+ +Y L V A DGG+P Sbjct: 937 ATDGDAGANSALTYSIAVGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEP 996 Query: 345 PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYE 402 P ++T +V L+E TPV T+ A+D D + RL Y Sbjct: 997 PLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGANGRLMYS 1056 Query: 403 ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINIT 460 I G G F I + G I++A L + Q Y++ V+ TD G + AMV I++T Sbjct: 1057 IESG-AHGHFRI-KDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVT 1114 Query: 461 DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN-AQITYSLSSEISNEAVAH 519 P N Y SV E V+ + +S ++ T+ SS Sbjct: 1115 ------PKPRNLTYDVSVLE-GEANVQVMDLKPAESHFNVSGGNFTFFDSS--------- 1158 Query: 520 HDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP 579 F IN T + LDRET + ++L ++ +GG ++ V ++V+D+ND P Sbjct: 1159 -GSMFSIN-GTNLRVGSTPLDRETAAQHILDISLTEGG--TIKGFVKVTVNVLDINDETP 1214 Query: 580 VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639 +F+ + ++ E +GT V ATD D G N + Y + EEG F I+ +G I Sbjct: 1215 LFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-AAGNEEGFFSINNKTGAI 1273 Query: 640 RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699 K LDRE+ + L +A DGG PP +ST V I++ D ND+PPV + + +SE Sbjct: 1274 SVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSET 1333 Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729 + I T + + A D D G N + YSI+ G Sbjct: 1334 AEIDTPVATVIASDKDIGANGRLMYSIESG 1363 Score = 233 bits (570), Expect = 5e-59 Identities = 214/716 (29%), Positives = 327/716 (45%), Gaps = 55/716 (7%) Query: 167 DNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSYRL 225 D PV A + A+D D+GAN + Y+I G F I DS SG +SL L Y Q +Y + Sbjct: 3369 DTPV-ATVIASDKDIGANGRLMYSIESG-AHGHFQIKDSSSGAISLAGMLSYNQRNNYIV 3426 Query: 226 VIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD 285 V+ DGGSP+ + ++I+++ PR T + SV E G + V+V Sbjct: 3427 VVNVTDGGSPALKSRAMVVIDVKP----KPRNLT--YDVSVLE----GEANVQVMDLKPA 3476 Query: 286 EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP 345 E T D +G++ + R G S LDRET A++ L ++ T+GG Sbjct: 3477 ESHFNVSGGNFTFFDSSGSMFSINGTNLRVG----STPLDRETAAQHILDISLTEGGTIK 3532 Query: 346 RSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI 403 T F + V + E E GT +T++ATD D ++ L Y I Sbjct: 3533 GFVKVTVNVLDINDETPL--FQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI 3590 Query: 404 TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITD 461 GN G FSI N G I+VA+ LD + +Y LTV A D G + T V I + D Sbjct: 3591 AVGNEEGFFSIN--NKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGD 3648 Query: 462 ANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521 AN+ PV ++A S+ E A I T V V A+D D+G N ++ YS+ S H Sbjct: 3649 ANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGANGRLMYSIES-------GAHG 3701 Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581 + + +GAI+ +L + Y++ V DGG P+L V V+DV P Sbjct: 3702 HFRIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMV---VIDVT---PKP 3755 Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641 + Y +++E V + + ++G + GS + + Sbjct: 3756 RNLTYDVSVLEGE-ANVQVMDLKPVVSHFNVSGGNFTFFN----SSGSMFSINGNNLSVG 3810 Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701 + LDRE+ A H L +GGT V V + + DIND P+F+S ++E Sbjct: 3811 STPLDRETAAQHVLDISLTEGGTI--KGFVKVTVNVLDINDETPLFQSPSFNVSVNEIER 3868 Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761 +GT + A D D G N+ + YSI G++ FS+ + G+ + LD E+ R Sbjct: 3869 LGTVFLTVSATDGDAGANSALTYSIAAGNEEGFFSINNKTGA----ISVAKQLDRET-RD 3923 Query: 762 KYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA 818 +Y L + A PPL + V I V D NDN PV++D I + + P V A Sbjct: 3924 QYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSETAAIDTPVATVIA 3983 Query: 819 YDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 D D+ +L Y I SG + + + + ++G+++L+ L+ N + V+VTDG Sbjct: 3984 SDKDIGANGRLMYSIESGAHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDG 4039 Score = 232 bits (568), Expect = 9e-59 Identities = 242/898 (26%), Positives = 384/898 (42%), Gaps = 85/898 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+ PV + + S+ E A T V T+ A+D+DIG N + Y+IE Sbjct: 3086 IQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGANGRLMYSIESGALGHF 3145 Query: 71 NPEDAXXXXXXXXXXVQDVFR---------IDGRSGALLTRASLDRE---KVARYTVLVK 118 +D + R DG S AL +RA + + K T V Sbjct: 3146 QIKDWSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAIVVIDVTPKPRNLTHDVS 3205 Query: 119 ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178 + + V A H N+ N + S ++++ ++ V P+ + A Sbjct: 3206 VLEGEANVQVMDLKPAESHFNVSGGNFTFFDSSGSMFSIN-GTNLRVGSTPLDRETAAQH 3264 Query: 179 A-DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSL-------VKTLDYEQVRSYRLVIRAQ 230 D+ I G ++ ++ ++ + L V + E++ + L + A Sbjct: 3265 ILDISLTEG---GTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSAT 3321 Query: 231 DGGSPSRSNTTQLLI--NIRDVNDNAPRFYTSLFQES---VSENVPIGYSIVRVQAYDAD 285 DG + + S T + N + + Y++LF S S+ I + V A D D Sbjct: 3322 DGDAGANSALTYSIAAGNEEGLVERTILKYSNLFDFSDLFCSQTAEIDTPVATVIASDKD 3381 Query: 286 EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP 345 G N L Y++ + G+ + D SG + +G L + Y ++V TDGG P Sbjct: 3382 IGANGRLMYSIESGAH-GHFQIK---DSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPA 3437 Query: 346 RSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITG 405 + A Y+V + E E V+ L ++ H+ ++G Sbjct: 3438 LKSRAMVVIDVKPKPRNLT------YDVSVLEGEA-NVQVMDLKPAES------HFNVSG 3484 Query: 406 GNTR---GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDA 462 GN S+ S NG L + PLD + +++L +S T+ G V +N+ D Sbjct: 3485 GNFTFFDSSGSMFSINGTNLRVGSTPLDRETAAQHILDISLTEGGTIKGFVKVTVNVLDI 3544 Query: 463 NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522 N+ P+F++ + SV E +GT L VSATD D G N+ +TYS+ AV + + Sbjct: 3545 NDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-------AVGNEEG 3597 Query: 523 QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582 F IN +TGAI+ K LDRET Y LTV A+DGG P L+ TT V I V D NDN PV + Sbjct: 3598 FFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQ 3657 Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI-DPASGVIRT 641 + ++ E A + T V+ V A+D D+G NGR+ Y ++ G F I D +SG I Sbjct: 3658 DAVIQVSLSETAEIDTPVATVIASDKDIGANGRLMYSIE--SGAHGHFRIKDSSSGAISL 3715 Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701 L + + DGG+P S +V I D+ P LT+ +S Sbjct: 3716 AGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVI---DVTPKP-----RNLTYDVS---- 3763 Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGD---DSNSFSLETRQGSDKAELVTMVDLDYES 758 GE D P V H+++ GG+ ++S S+ + G++ + V LD E+ Sbjct: 3764 --VLEGEANVQVMDLKP-VVSHFNVSGGNFTFFNSSGSMFSINGNNLS--VGSTPLDRET 3818 Query: 759 PRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMK--DFQIIFNNYKDCFPVGPFGRV 816 + + + V+V + V D+ND P+ + F + N + V F V Sbjct: 3819 AAQHVLDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTV--FLTV 3876 Query: 817 PAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 A D D L Y I +GN +N TG+++++ QL+ T+ V DG Sbjct: 3877 SATDGDAGANSALTYSIAAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDG 3934 Score = 222 bits (543), Expect = 1e-55 Identities = 145/435 (33%), Positives = 216/435 (49%), Gaps = 28/435 (6%) Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 +++ G +Q +D +G +S+ K LD E Y L + AQDGG P ++TT + I + D Sbjct: 1731 SVLEGEANVQV-MDLKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGD 1789 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 NDN P ++ + S+SE I + V A D D G N L Y++ + G+ + Sbjct: 1790 ANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESGAH-GHFQIK- 1847 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 D SG + +G L + Y ++V TDGG P + A Sbjct: 1848 --DSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVTPKPRNLT----- 1900 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT---RGRFSITSQNGRGLITVA 426 Y+V + E E V+ L + H+ ++GGN S+ S NG L + Sbjct: 1901 -YDVSVLEGEA-NVQVMDLKPVVS------HFNVSGGNFTFFNSSGSMFSINGNNLRVGS 1952 Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 PLD + ++VL +S T+ G V +N+ D N+ P+F++ + SV E +GT Sbjct: 1953 TPLDRETAAQHVLDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGT 2012 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 L VSATD D G N+ +TYS+ A + + F IN +TGAI+ K LDRET Sbjct: 2013 VFLTVSATDGDAGANSALTYSI-------AAGNEEGFFSINNKTGAISVAKQLDRETRDQ 2065 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y LTV A+DGG P L+ TT V I V D NDN PV + + ++ E A + T V+ V A+ Sbjct: 2066 YTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSETAEIDTPVATVIAS 2125 Query: 607 DADVGLNGRIHYELD 621 D D+G NGR+ Y ++ Sbjct: 2126 DKDIGANGRLMYSIE 2140 Score = 222 bits (542), Expect = 1e-55 Identities = 221/793 (27%), Positives = 354/793 (44%), Gaps = 88/793 (11%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 FRI+ +G L+ +LDRE + ++ AS S + S TA + I D NDN P Sbjct: 2464 FRINSSTGDLIVNKTLDREAMGNGLGSLRFEVYASDSSSQGSLTAIL--TITDINDNAPA 2521 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209 F TVS E+ + +A + ATDAD N+ I + I+ GN FSID ++GD+ Sbjct: 2522 FQNTPLTVSCSENRPI--GLTVATLTATDADATTNAIITFVIVSGNEGEAFSIDKVTGDI 2579 Query: 210 SLVKTLDYEQ-VRSYRLVIRAQDGGSPSRSNTTQLL-INIRDVNDNAPRFYTSLFQESVS 267 ++ K LDY++ R Y L I A + + + ++ INI DV+D F L++ + Sbjct: 2580 TISKPLDYDKGPRVYTLNISAMNNHTDLMLQSFGVVTINITDVDDLPANFSQKLYEAHID 2639 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 +N P+G I +V A D D +NA + Y++ G + I+ SG V G L Sbjct: 2640 KNSPLGSLITQVHAKDMDS-LNAPVEYSIYPDSDPGGL---FAINKTSGEVTVDGNL--- 2692 Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387 Y L+V A +S T + Y+V + E E PV+ Sbjct: 2693 RNGVYSLIVNA-------KSTTQPLAFTLVKVTVSTLSNLT--YDVSILEGEA-NVPVMD 2742 Query: 388 LTATDADEDNRLHYEITGGNTR---GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444 L ++ H+ ++GGN S+ S NG L + PLD + +++L +S T Sbjct: 2743 LKPAES------HFNVSGGNFTFFDSSGSMFSINGTNLRVGSTPLDRETAAQHILDISLT 2796 Query: 445 DSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504 + GG + TA + D P+ T + A+D D+G N ++ Sbjct: 2797 E-GG-------------------TIKGFVKTAEI--DTPVATVI----ASDKDIGANGRL 2830 Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT 564 YS+ E+ AH Q + + +GAI+ +L + Y++ V DGG P+L Sbjct: 2831 MYSI------ESGAHGHFQ-IKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSR 2883 Query: 565 TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624 V V+DV +P + Y +++E V + ++ ++G D Sbjct: 2884 AMV---VIDV---KPKPRNLTYDVSVLEGE-ANVQVMDLKPAESHFNVSGGNFTFFD--- 2933 Query: 625 REEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP 684 GS + + + LDRE+ A H L +GGT V V + + DIND Sbjct: 2934 -SSGSMFSINGTNLRVGSTPLDRETAAQHILDISLTEGGT--IKGFVKVTVNVLDINDET 2990 Query: 685 PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD 744 P+F+S ++E +GT + A D D G N+ + YSI G++ FS+ + G+ Sbjct: 2991 PLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAVGNEEGFFSINNKTGA- 3049 Query: 745 KAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801 + LD E+ R +Y L + A PPL + V I V D NDN PV++D I Sbjct: 3050 ---ISVAKQLDRET-RDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQV 3105 Query: 802 NNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNV 859 + + P V A D D+ +L Y I SG + + + ++G+++L+ L+ N Sbjct: 3106 SLSETAEIDTPVATVIASDKDIGANGRLMYSIESGALGHFQIKDWSSGAISLAGMLSYNQ 3165 Query: 860 PKLATMEVSVTDG 872 + V+VTDG Sbjct: 3166 RNNYIVVVNVTDG 3178 Score = 220 bits (537), Expect = 5e-55 Identities = 240/871 (27%), Positives = 372/871 (42%), Gaps = 113/871 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+ PV + S+ E A T V T+ A+D+DIG N + Y+IE Sbjct: 1309 IQVGDANDNPPVIQDAVIRVSLSETAEIDTPVATVIASDKDIGANGRLMYSIE------- 1361 Query: 71 NPEDAXXXXXXXXXXVQDVFRI-DGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 F+I D SGA+ L + Y V+V TD SP Sbjct: 1362 -------------SGAHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPA--- 1405 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L S A + +++ P+ TY VSV E + N + +K ++ + + Sbjct: 1406 LKSRAMVVIDV------KPKPRNLTYDVSVLEGEA---NVQVMDLKPAESHFNVSGG-NF 1455 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 + M FSI+ + V LD E + L I +GG+ ++ +N+ D Sbjct: 1456 TFFDSSGSM-FSINGTNLRVGSTP-LDRETAAQHILDISLTEGGTIK--GFVKVTVNVLD 1511 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 +ND P F + F SV+E +G + V A D D G N+ LTY++ GN + Sbjct: 1512 INDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIA----AGNEEGFF 1567 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 +I+ ++G + + QLDRET+ +Y L V A DGG+PP ++T Sbjct: 1568 SINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDA 1627 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 V L+E TPV T+ A+D D G N R +SI S G + Sbjct: 1628 VIRVSLSETAAIDTPVATVIASDKD---------IGANGRLMYSIES-GAHGHFQI---- 1673 Query: 430 DFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 K ++++ S + + +V +N+TD + P ++ ++ Sbjct: 1674 --KDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGS--PALKSR--------------AMV 1715 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 V+ T +TY +S + EA V++ +TGAI+ K LDRET Y L Sbjct: 1716 VIDVTPKP----RNLTYDVSV-LEGEANVQ-----VMDLKTGAISVAKQLDRETRDQYTL 1765 Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 TV A+DGG P L+ TT V I V D NDN PV + + ++ E A + T V+ V A+D D Sbjct: 1766 TVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKD 1825 Query: 610 VGLNGRIHYELDPKDREEGSFVI-DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 +G NGR+ Y ++ G F I D +SG I L + + DGG+P Sbjct: 1826 IGANGRLMYSIE--SGAHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALK 1883 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 S +V I D+ P LT+ +S GE D P V H+++ G Sbjct: 1884 SRAMVVI---DVTPKP-----RNLTYDVS------VLEGEANVQVMDLKP-VVSHFNVSG 1928 Query: 729 GD---DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVT 785 G+ ++S S+ + G++ V LD E+ + + + V+V + V Sbjct: 1929 GNFTFFNSSGSMFSINGNNLR--VGSTPLDRETAAQHVLDISLTEGGTIKGFVKVTVNVL 1986 Query: 786 DVNDNAPVMK--DFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLIL 841 D+ND P+ + F + N + V F V A D D L Y I +GN Sbjct: 1987 DINDETPLFQSPSFNVSVNEIERLGTV--FLTVSATDGDAGANSALTYSIAAGNEEGFFS 2044 Query: 842 LNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 +N TG+++++ QL+ T+ V DG Sbjct: 2045 INNKTGAISVAKQLDRETRDQYTLTVMAQDG 2075 Score = 218 bits (533), Expect = 2e-54 Identities = 194/646 (30%), Positives = 294/646 (45%), Gaps = 72/646 (11%) Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 E I + V A D D G N L Y++ + G+ + D SG + +G L Sbjct: 484 ETAEIDTPVATVIASDKDIGANGRLMYSI-ESGALGHFQIK---DWSSGAISLAGMLSYN 539 Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387 + Y ++V TDGG P + A ++V + E E V+ Sbjct: 540 QRNNYIVVVNVTDGGSPALKSRAIVVIDVTPKPRNLT------HDVSVLEGEA-NVQVMD 592 Query: 388 LTATDADEDNRLHYEITGGNTR---GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444 L ++ H+ ++GGN S+ S NG L + PLD + +++L +S T Sbjct: 593 LKPAES------HFNVSGGNFTFFDSSGSMFSINGTNLRVGSTPLDRETAAQHILDISLT 646 Query: 445 DSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504 + G V +N+ D N+ P+F++ + SV E +GT L VSATD D G N+ + Sbjct: 647 EGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSAL 706 Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT 564 TYS+ A + + F IN +TGAI+ K LDRET Y LTV A+DGG P L+ T Sbjct: 707 TYSI-------AAGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNST 759 Query: 565 TDVEISVVDVNDNEPVFKQQLYTANIME----------DALVGTSVSQVGATDA------ 608 T V I V D NDN PV + + ++ E AL ++ + T Sbjct: 760 TAVAIQVGDANDNPPVIQDAVIRVSLSEVVVNVTDGGSPALKSRAMVVIDVTPKPRNLTY 819 Query: 609 DVG-LNGRIHYE-LDPKDREE------GSFVIDPASG----VIRTN-----KALDRESVA 651 DV L G + + +D K E G+F +SG + TN LDRE+ A Sbjct: 820 DVSVLEGEANVQVMDLKPAESHFNVSGGNFTFFDSSGSMFSINGTNLRVGSTPLDRETAA 879 Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711 H L +GGT V V + + DIND P+F+S ++E +GT + A Sbjct: 880 QHILDISLTEGGT--IKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSA 937 Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA-- 769 D D G N+ + YSI G++ FS+ + G+ + LD E+ R +Y L + A Sbjct: 938 TDGDAGANSALTYSIAVGNEEGFFSINNKTGA----ISVAKQLDRET-RDQYTLTVMAQD 992 Query: 770 -ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDK 826 PPL + V I V D NDN PV++D I + + P V A D D+ + Sbjct: 993 GGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGANGR 1052 Query: 827 LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 L Y I SG + + + + ++G+++L+ L+ N + V+VTDG Sbjct: 1053 LMYSIESGAHGHFRIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDG 1098 Score = 203 bits (496), Expect = 5e-50 Identities = 182/605 (30%), Positives = 280/605 (46%), Gaps = 57/605 (9%) Query: 158 SVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI-DSLSGDVSLVKTLD 216 ++D + + D PV A + A+D D+GAN + Y+I G F I D SG +SL L Sbjct: 480 TLDRETAEIDTPV-ATVIASDKDIGANGRLMYSIESG-ALGHFQIKDWSSGAISLAGMLS 537 Query: 217 YEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSI 276 Y Q +Y +V+ DGGSP+ + ++I++ N + L E+ NV + + Sbjct: 538 YNQRNNYIVVVNVTDGGSPALKSRAIVVIDVTPKPRNLTHDVSVLEGEA---NVQV-MDL 593 Query: 277 VRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLV 336 +++ G N T D +G++ + R G S LDRET A++ L + Sbjct: 594 KPAESHFNVSGGN------FTFFDSSGSMFSINGTNLRVG----STPLDRETAAQHILDI 643 Query: 337 TATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD-- 394 + T+GG T F + V + E E GT +T++ATD D Sbjct: 644 SLTEGGTIKGFVKVT--VNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAG 701 Query: 395 EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDT 452 ++ L Y I GN G FSI N G I+VA+ LD + +Y LTV A D G + T Sbjct: 702 ANSALTYSIAAGNEEGFFSI--NNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNST 759 Query: 453 AMVQINITDANNYAPVFENAPYTASVFE----------DAPIGTTVLVVSATDS------ 496 V I + DAN+ PV ++A S+ E A ++V+ T Sbjct: 760 TAVAIQVGDANDNPPVIQDAVIRVSLSEVVVNVTDGGSPALKSRAMVVIDVTPKPRNLTY 819 Query: 497 DVGI-----NAQITYSLSSE----ISNEAVAHHD---QQFVINPQTGAITTNKLLDRETM 544 DV + N Q+ +E +S D F IN + + L DRET Sbjct: 820 DVSVLEGEANVQVMDLKPAESHFNVSGGNFTFFDSSGSMFSINGTNLRVGSTPL-DRETA 878 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 + ++L ++ +GG ++ V ++V+D+ND P+F+ + ++ E +GT V Sbjct: 879 AQHILDISLTEGG--TIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVS 936 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 ATD D G N + Y + EEG F I+ +G I K LDRE+ + L +A DGG Sbjct: 937 ATDGDAGANSALTYSI-AVGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGE 995 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 PP +ST V I++ D ND+PPV + + +SE + I T + + A D D G N + Y Sbjct: 996 PPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGANGRLMY 1055 Query: 725 SIKGG 729 SI+ G Sbjct: 1056 SIESG 1060 Score = 192 bits (468), Expect = 1e-46 Identities = 171/576 (29%), Positives = 256/576 (44%), Gaps = 56/576 (9%) Query: 276 IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL 335 + V A D D G N L Y++ + G+ + D SG + +G L + Y ++ Sbjct: 2814 VATVIASDKDIGANGRLMYSIESGAH-GHFQIK---DSSSGAISLAGMLSYNQRNNYIVV 2869 Query: 336 VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395 V TDGG P + A Y+V + E E V+ L ++ Sbjct: 2870 VNVTDGGSPALKSRAMVVIDVKPKPRNLT------YDVSVLEGEA-NVQVMDLKPAES-- 2920 Query: 396 DNRLHYEITGGNTR---GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT 452 H+ ++GGN S+ S NG L + PLD + +++L +S T+ G Sbjct: 2921 ----HFNVSGGNFTFFDSSGSMFSINGTNLRVGSTPLDRETAAQHILDISLTEGGTIKGF 2976 Query: 453 AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512 V +N+ D N+ P+F++ + SV E +GT L VSATD D G N+ +TYS+ Sbjct: 2977 VKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI---- 3032 Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572 AV + + F IN +TGAI+ K LDRET Y LTV A+DGG P L+ TT V I V Sbjct: 3033 ---AVGNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVG 3089 Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632 D NDN PV + + ++ E A + T V+ V A+D D+G NGR+ Y ++ G F I Sbjct: 3090 DANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKDIGANGRLMYSIE--SGALGHFQI 3147 Query: 633 -DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691 D +SG I L + + DGG+P S IV I D+ P D Sbjct: 3148 KDWSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAIVVI---DVTPKPRNLTHD- 3203 Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS---NSFSLETRQGSDKAEL 748 + GE D P A H+++ GG+ + +S S+ + G++ Sbjct: 3204 ----------VSVLEGEANVQVMDLKP-AESHFNVSGGNFTFFDSSGSMFSINGTNLR-- 3250 Query: 749 VTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMK--DFQIIFNNYKD 806 V LD E+ + + + V+V + V D+ND P+ + F + N + Sbjct: 3251 VGSTPLDRETAAQHILDISLTEGGTIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIER 3310 Query: 807 CFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLI 840 V F V A D D L Y I +GN L+ Sbjct: 3311 LGTV--FLTVSATDGDAGANSALTYSIAAGNEEGLV 3344 Score = 190 bits (464), Expect = 4e-46 Identities = 138/443 (31%), Positives = 210/443 (47%), Gaps = 31/443 (6%) Query: 292 LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 LTY ++ + NV + +D ++G + + QLDRET+ +Y L V A DGG+PP ++T Sbjct: 1726 LTYDVSVLEGEANVQV---MDLKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTA 1782 Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTR 409 V L+E TPV T+ A+D D + RL Y I G Sbjct: 1783 VAIQVGDANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIESG-AH 1841 Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAP 467 G F I + G I++A L + Q Y++ V+ TD G + AMV I++T P Sbjct: 1842 GHFQIKDSSS-GAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAMVVIDVT------P 1894 Query: 468 VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA-QITYSLSSEISNEAVAHHDQQFVI 526 N Y SV E V+ + S ++ T+ SS F I Sbjct: 1895 KPRNLTYDVSVLE-GEANVQVMDLKPVVSHFNVSGGNFTFFNSS----------GSMFSI 1943 Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586 N + + L DRET + ++L ++ +GG ++ V ++V+D+ND P+F+ + Sbjct: 1944 NGNNLRVGSTPL-DRETAAQHVLDISLTEGG--TIKGFVKVTVNVLDINDETPLFQSPSF 2000 Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646 ++ E +GT V ATD D G N + Y + EEG F I+ +G I K LD Sbjct: 2001 NVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-AAGNEEGFFSINNKTGAISVAKQLD 2059 Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706 RE+ + L +A DGG PP +ST V I++ D ND+PPV + + +SE + I T + Sbjct: 2060 RETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSLSETAEIDTPV 2119 Query: 707 GEIRAHDPDEGPNAVVHYSIKGG 729 + A D D G N + YSI+ G Sbjct: 2120 ATVIASDKDIGANGRLMYSIESG 2142 Score = 168 bits (409), Expect = 2e-39 Identities = 166/599 (27%), Positives = 261/599 (43%), Gaps = 70/599 (11%) Query: 36 ASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRI-DG 94 A T V T+ A+D+DIG N + Y+IE F+I D Sbjct: 2808 AEIDTPVATVIASDKDIGANGRLMYSIE--------------------SGAHGHFQIKDS 2847 Query: 95 RSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKT 154 SGA+ L + Y V+V TD SP L S A + +++ P+ T Sbjct: 2848 SSGAISLAGMLSYNQRNNYIVVVNVTDGGSPA---LKSRAMVVIDV------KPKPRNLT 2898 Query: 155 YTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT 214 Y VSV E + N + +K ++ + + + M FSI+ + V Sbjct: 2899 YDVSVLEGEA---NVQVMDLKPAESHFNVSGG-NFTFFDSSGSM-FSINGTNLRVGST-P 2952 Query: 215 LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY 274 LD E + L I +GG + ++ +N+ D+ND P F + F SV+E +G Sbjct: 2953 LDRETAAQHILDISLTEGG--TIKGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGT 3010 Query: 275 SIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQL 334 + V A D D G N+ LTY++ GN + +I+ ++G + + QLDRET+ +Y L Sbjct: 3011 VFLTVSATDGDAGANSALTYSIA----VGNEEGFFSINNKTGAISVAKQLDRETRDQYTL 3066 Query: 335 LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394 V A DGG+PP ++T +V L+E TPV T+ A+D D Sbjct: 3067 TVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEIDTPVATVIASDKD 3126 Query: 395 --EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS-- 450 + RL Y I G G F I + G I++A L + Q Y++ V+ TD G + Sbjct: 3127 IGANGRLMYSIESG-ALGHFQIKDWSS-GAISLAGMLSYNQRNNYIVVVNVTDGGSPALK 3184 Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN-AQITYSLS 509 A+V I++T P N + SV E V+ + +S ++ T+ S Sbjct: 3185 SRAIVVIDVT------PKPRNLTHDVSVLE-GEANVQVMDLKPAESHFNVSGGNFTFFDS 3237 Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569 S F IN T + LDRET + ++L ++ +GG ++ V + Sbjct: 3238 S----------GSMFSIN-GTNLRVGSTPLDRETAAQHILDISLTEGG--TIKGFVKVTV 3284 Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG 628 +V+D+ND P+F+ + ++ E +GT V ATD D G N + Y + EEG Sbjct: 3285 NVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSI-AAGNEEG 3342 Score = 149 bits (361), Expect = 1e-33 Identities = 127/421 (30%), Positives = 193/421 (45%), Gaps = 32/421 (7%) Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASV 478 G I+VA+ LD + +Y LTV A D G + T V I + DAN+ PV ++A S+ Sbjct: 1747 GAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPVIQDAVIRVSL 1806 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 E A I T V V A+D D+G N ++ YS+ E+ AH Q + + +GAI+ + Sbjct: 1807 SETAAIDTPVATVIASDKDIGANGRLMYSI------ESGAHGHFQ-IKDSSSGAISLAGM 1859 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 L + Y++ V DGG P+L V V+DV P + Y +++E Sbjct: 1860 LSYNQRNNYIVVVNVTDGGSPALKSRAMV---VIDVT---PKPRNLTYDVSVLEGE-ANV 1912 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 V + + ++G + GS + + + LDRE+ A H L Sbjct: 1913 QVMDLKPVVSHFNVSGGNFTFFN----SSGSMFSINGNNLRVGSTPLDRETAAQHVLDIS 1968 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 +GGT V V + + DIND P+F+S ++E +GT + A D D G Sbjct: 1969 LTEGGTI--KGFVKVTVNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGA 2026 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLW 775 N+ + YSI G++ FS+ + G+ + LD E+ R +Y L + A PPL Sbjct: 2027 NSALTYSIAAGNEEGFFSINNKTGA----ISVAKQLDRET-RDQYTLTVMAQDGGEPPLN 2081 Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILS 833 + V I V D NDN PV++D I + + P V A D D+ +L Y I S Sbjct: 2082 STTAVAIQVGDANDNPPVIQDAVIRVSLSETAEIDTPVATVIASDKDIGANGRLMYSIES 2141 Query: 834 G 834 G Sbjct: 2142 G 2142 Score = 131 bits (316), Expect = 3e-28 Identities = 120/403 (29%), Positives = 182/403 (45%), Gaps = 44/403 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NVLD ND +P+F+ + SV E GT LT+ ATD D G N+ + Y+I + Sbjct: 2981 VNVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAV------ 3034 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F I+ ++GA+ LDRE +YT+ V A D P L Sbjct: 3035 -------------GNEEGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEP---PL 3078 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +ST + + + D NDN P + VS+ E + D PV A + A+D D+GAN + Y+ Sbjct: 3079 NSTTAVAIQVGDANDNPPVIQDAVIQVSLSETAEI-DTPV-ATVIASDKDIGANGRLMYS 3136 Query: 191 IIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I G F I D SG +SL L Y Q +Y +V+ DGGSP+ + ++I++ Sbjct: 3137 IESG-ALGHFQIKDWSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPALKSRAIVVIDVTP 3195 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 N + L E+ NV + + +++ G N T D +G++ Sbjct: 3196 KPRNLTHDVSVLEGEA---NVQV-MDLKPAESHFNVSGGN------FTFFDSSGSMFSIN 3245 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 + R G S LDRET A++ L ++ T+GG T F Sbjct: 3246 GTNLRVG----STPLDRETAAQHILDISLTEGGTIKGFVKVT--VNVLDINDETPLFQSP 3299 Query: 370 QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRG 410 + V + E E GT +T++ATD D ++ L Y I GN G Sbjct: 3300 SFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIAAGNEEG 3342 Score = 126 bits (304), Expect = 9e-27 Identities = 125/427 (29%), Positives = 184/427 (43%), Gaps = 53/427 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+ PV + S+ E A+ T V T+ A+D+DIG N + Y+IE Sbjct: 1785 IQVGDANDNPPVIQDAVIRVSLSETAAIDTPVATVIASDKDIGANGRLMYSIE------- 1837 Query: 71 NPEDAXXXXXXXXXXVQDVFRI-DGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 F+I D SGA+ L + Y V+V TD SP Sbjct: 1838 -------------SGAHGHFQIKDSSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPA--- 1881 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE---DISVTD-NPVIAKIKATDADVGANS 185 L S A + +++ P+ TY VSV E ++ V D PV++ + G N Sbjct: 1882 LKSRAMVVIDVT------PKPRNLTYDVSVLEGEANVQVMDLKPVVSHFNVS----GGN- 1930 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 + + M FSI+ + V LD E + L I +GG+ ++ + Sbjct: 1931 ---FTFFNSSGSM-FSINGNNLRVGSTP-LDRETAAQHVLDISLTEGGTIK--GFVKVTV 1983 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 N+ D+ND P F + F SV+E +G + V A D D G N+ LTY++ GN Sbjct: 1984 NVLDINDETPLFQSPSFNVSVNEIERLGTVFLTVSATDGDAGANSALTYSIA----AGNE 2039 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 + +I+ ++G + + QLDRET+ +Y L V A DGG+PP ++T Sbjct: 2040 EGFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDGGEPPLNSTTAVAIQVGDANDNPPV 2099 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLI 423 V L+E TPV T+ A+D D + RL Y I G G F I + Sbjct: 2100 IQDAVIRVSLSETAEIDTPVATVIASDKDIGANGRLMYSIESG-AHGHFQIKDSSKCRRY 2158 Query: 424 TVAQPLD 430 TV D Sbjct: 2159 TVFNSFD 2165 Score = 103 bits (246), Expect = 9e-20 Identities = 86/281 (30%), Positives = 129/281 (45%), Gaps = 16/281 (5%) Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525 AP +P+ + V + + TT + + G N ITYSL E +AH F Sbjct: 2416 APPTFGSPFWSDVLPE--VNTTAGTIITRLTATGGNGTITYSL------EDIAH--PWFR 2465 Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD-TTDVEISVVDVNDNEPVFKQQ 584 IN TG + NK LDRE M L ++ S S + +++ D+NDN P F+ Sbjct: 2466 INSSTGDLIVNKTLDREAMGNGLGSLRFEVYASDSSSQGSLTAILTITDINDNAPAFQNT 2525 Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA 644 T + E+ +G +V+ + ATDAD N I + + E +F ID +G I +K Sbjct: 2526 PLTVSCSENRPIGLTVATLTATDADATTNAIITFVI-VSGNEGEAFSIDKVTGDITISKP 2584 Query: 645 LDRE-SVATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 LD + + L A++ T S +V I I D++D P F +I +NSP+ Sbjct: 2585 LDYDKGPRVYTLNISAMNNHTDLMLQSFGVVTINITDVDDLPANFSQKLYEAHIDKNSPL 2644 Query: 703 GTTIGEIRAHDPDEGPNAVVHYSI-KGGDDSNSFSLETRQG 742 G+ I ++ A D D NA V YSI D F++ G Sbjct: 2645 GSLITQVHAKDMD-SLNAPVEYSIYPDSDPGGLFAINKTSG 2684 Score = 95.5 bits (227), Expect = 2e-17 Identities = 92/318 (28%), Positives = 144/318 (45%), Gaps = 42/318 (13%) Query: 33 REGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRI 92 RE A T V T+ A+D+DIG N + Y+IE F+I Sbjct: 483 RETAEIDTPVATVIASDKDIGANGRLMYSIE--------------------SGALGHFQI 522 Query: 93 -DGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151 D SGA+ L + Y V+V TD SP L S A + +++ P+ Sbjct: 523 KDWSSGAISLAGMLSYNQRNNYIVVVNVTDGGSPA---LKSRAIVVIDVT------PKPR 573 Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSL 211 T+ VSV E + N + +K ++ + + + M FSI+ + V Sbjct: 574 NLTHDVSVLEGEA---NVQVMDLKPAESHFNVSGG-NFTFFDSSGSM-FSINGTNLRVGS 628 Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271 LD E + L I +GG+ ++ +N+ D+ND P F + F SV+E Sbjct: 629 TP-LDRETAAQHILDISLTEGGTIK--GFVKVTVNVLDINDETPLFQSPSFNVSVNEIER 685 Query: 272 IGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK 331 +G + V A D D G N+ LTY++ GN + +I+ ++G + + QLDRET+ + Sbjct: 686 LGTVFLTVSATDGDAGANSALTYSIA----AGNEEGFFSINNKTGAISVAKQLDRETRDQ 741 Query: 332 YQLLVTATDGGDPPRSAT 349 Y L V A DGG+PP ++T Sbjct: 742 YTLTVMAQDGGEPPLNST 759 Score = 89.0 bits (211), Expect = 2e-15 Identities = 85/302 (28%), Positives = 140/302 (46%), Gaps = 22/302 (7%) Query: 579 PVFKQQLYTANIME-DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637 P F ++ + E + GT ++++ AT G NG I Y L+ D F I+ ++G Sbjct: 2418 PTFGSPFWSDVLPEVNTTAGTIITRLTAT----GGNGTITYSLE--DIAHPWFRINSSTG 2471 Query: 638 VIRTNKALDRESVATH--DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695 + NK LDRE++ L+ + Q S + + I DIND+ P F++ LT Sbjct: 2472 DLIVNKTLDREAMGNGLGSLRFEVYASDSSSQGSLTAI-LTITDINDNAPAFQNTPLTVS 2530 Query: 696 ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755 SEN PIG T+ + A D D NA++ + I G++ +FS++ G ++ LD Sbjct: 2531 CSENRPIGLTVATLTATDADATTNAIITFVIVSGNEGEAFSIDKVTG----DITISKPLD 2586 Query: 756 YESPRKKYELVIRAASP----PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811 Y+ + Y L I A + L + V I +TDV D+ P ++ + P+G Sbjct: 2587 YDKGPRVYTLNISAMNNHTDLMLQSFGVVTINITDV-DDLPANFSQKLYEAHIDKNSPLG 2645 Query: 812 P-FGRVPAYDAD-VTDKLQYRILSGNN-ANLILLNETTGSMTLSPQLNTNVPKLATMEVS 868 +V A D D + ++Y I ++ L +N+T+G +T+ L V L S Sbjct: 2646 SLITQVHAKDMDSLNAPVEYSIYPDSDPGGLFAINKTSGEVTVDGNLRNGVYSLIVNAKS 2705 Query: 869 VT 870 T Sbjct: 2706 TT 2707 Score = 88.6 bits (210), Expect = 2e-15 Identities = 129/515 (25%), Positives = 206/515 (40%), Gaps = 57/515 (11%) Query: 373 VELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 V +E+ P G V TLTATDAD + + I GN FSI G IT+++PLD Sbjct: 279 VSCSENRPIGLTVATLTATDADATTNAIITFVIVSGNEGEAFSIDKVTGD--ITISKPLD 336 Query: 431 FKQ-ERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 ++ R Y L +SA ++ +V INITD ++ F Y A + +++P+ Sbjct: 337 YENGPRVYTLNISAMNNHTDLMLQSFGVVTINITDVDDLPANFSQKLYEAHIDKNSPLPC 396 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 +T + + Y + + + D +N G I T Sbjct: 397 FCFAWKSTPTSRCY--RHIYFPGAPPTFGSPFWSDVLPEVNTTAGTIITR---------- 444 Query: 547 YLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 LT T +G + SL D ++ + + + + L D V T + A Sbjct: 445 --LTATGGNGTITYSLEDIAHPWFR-INSSTGDLIVNKTLDRETAEIDTPVATVI----A 497 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVI-DPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 +D D+G NGR+ Y ++ G F I D +SG I L + + DGG+ Sbjct: 498 SDKDIGANGRLMYSIE--SGALGHFQIKDWSSGAISLAGMLSYNQRNNYIVVVNVTDGGS 555 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 P S IV I D+ P D + GE D P A H+ Sbjct: 556 PALKSRAIVVI---DVTPKPRNLTHD-----------VSVLEGEANVQVMDLKP-AESHF 600 Query: 725 SIKGGDDS---NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781 ++ GG+ + +S S+ + G++ V LD E+ + + + V+V Sbjct: 601 NVSGGNFTFFDSSGSMFSINGTNLR--VGSTPLDRETAAQHILDISLTEGGTIKGFVKVT 658 Query: 782 ILVTDVNDNAPVMK--DFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNA 837 + V D+ND P+ + F + N + V F V A D D L Y I +GN Sbjct: 659 VNVLDINDETPLFQSPSFNVSVNEIERLGTV--FLTVSATDGDAGANSALTYSIAAGNEE 716 Query: 838 NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 +N TG+++++ QL+ T+ V DG Sbjct: 717 GFFSINNKTGAISVAKQLDRETRDQYTLTVMAQDG 751 Score = 81.0 bits (191), Expect = 4e-13 Identities = 49/140 (35%), Positives = 73/140 (52%), Gaps = 4/140 (2%) Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194 T + I D NDN P F TVS E+ + +A + ATDAD N+ I + I+ G Sbjct: 257 TAILTITDINDNAPAFQNTPLTVSCSENRPI--GLTVATLTATDADATTNAIITFVIVSG 314 Query: 195 NTQMQFSIDSLSGDVSLVKTLDYEQ-VRSYRLVIRAQDGGSPSRSNTTQLL-INIRDVND 252 N FSID ++GD+++ K LDYE R Y L I A + + + ++ INI DV+D Sbjct: 315 NEGEAFSIDKVTGDITISKPLDYENGPRVYTLNISAMNNHTDLMLQSFGVVTINITDVDD 374 Query: 253 NAPRFYTSLFQESVSENVPI 272 F L++ + +N P+ Sbjct: 375 LPANFSQKLYEAHIDKNSPL 394 Score = 77.8 bits (183), Expect = 4e-12 Identities = 53/136 (38%), Positives = 72/136 (52%), Gaps = 9/136 (6%) Query: 457 INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA 516 + ITD N+ AP F+N P T S E+ PIG TV ++ATD+D NA IT+ + S EA Sbjct: 260 LTITDINDNAPAFQNTPLTVSCSENRPIGLTVATLTATDADATTNAIITFVIVSGNEGEA 319 Query: 517 VAHHDQQFVINPQTGAITTNKLLDRET-MSGYLLTVTARDGGVP-SLSDTTDVEISVVDV 574 F I+ TG IT +K LD E Y L ++A + L V I++ DV Sbjct: 320 -------FSIDKVTGDITISKPLDYENGPRVYTLNISAMNNHTDLMLQSFGVVTINITDV 372 Query: 575 NDNEPVFKQQLYTANI 590 +D F Q+LY A+I Sbjct: 373 DDLPANFSQKLYEAHI 388 Score = 64.9 bits (151), Expect = 3e-08 Identities = 42/136 (30%), Positives = 68/136 (50%), Gaps = 3/136 (2%) Query: 569 ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG 628 +++ D+NDN P F+ T + E+ +G +V+ + ATDAD N I + + E Sbjct: 260 LTITDINDNAPAFQNTPLTVSCSENRPIGLTVATLTATDADATTNAIITFVI-VSGNEGE 318 Query: 629 SFVIDPASGVIRTNKALDRES-VATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPV 686 +F ID +G I +K LD E+ + L A++ T S +V I I D++D P Sbjct: 319 AFSIDKVTGDITISKPLDYENGPRVYTLNISAMNNHTDLMLQSFGVVTINITDVDDLPAN 378 Query: 687 FESDCLTFYISENSPI 702 F +I +NSP+ Sbjct: 379 FSQKLYEAHIDKNSPL 394 Score = 64.1 bits (149), Expect = 5e-08 Identities = 41/119 (34%), Positives = 63/119 (52%), Gaps = 8/119 (6%) Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734 + I DIND+ P F++ LT SEN PIG T+ + A D D NA++ + I G++ + Sbjct: 260 LTITDINDNAPAFQNTPLTVSCSENRPIGLTVATLTATDADATTNAIITFVIVSGNEGEA 319 Query: 735 FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP----PLWNDVRVEILVTDVND 789 FS++ G ++ LDYE+ + Y L I A + L + V I +TDV+D Sbjct: 320 FSIDKVTG----DITISKPLDYENGPRVYTLNISAMNNHTDLMLQSFGVVTINITDVDD 374 Score = 58.8 bits (136), Expect = 2e-06 Identities = 59/227 (25%), Positives = 101/227 (44%), Gaps = 29/227 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND++P F+ S E G TV TL ATD D NA + + I V+ + Sbjct: 2510 LTITDINDNAPAFQNTPLTVSCSENRPIGLTVATLTATDADATTNAIITFVI--VSGNE- 2566 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSDR 129 + F ID +G + LD +K R YT+ + A + + + Sbjct: 2567 ----------------GEAFSIDKVTGDITISKPLDYDKGPRVYTLNISAMNNHTDL--M 2608 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L S + +NI D +D FS+K Y +D++ + +I ++ A D D N+ + Y Sbjct: 2609 LQSFGVVTINITDVDDLPANFSQKLYEAHIDKNSPL--GSLITQVHAKDMD-SLNAPVEY 2665 Query: 190 AII-GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP 235 +I + F+I+ SG+V++ L + Y L++ A+ P Sbjct: 2666 SIYPDSDPGGLFAINKTSGEVTVDGNL---RNGVYSLIVNAKSTTQP 2709 Score = 56.0 bits (129), Expect = 1e-05 Identities = 35/104 (33%), Positives = 53/104 (50%), Gaps = 5/104 (4%) Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295 +R ++ I D+NDNAP F + S SEN PIG ++ + A DAD NA +T+ Sbjct: 251 TRKGKLTAILTITDINDNAPAFQNTPLTVSCSENRPIGLTVATLTATDADATTNAIITFV 310 Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK-YQLLVTA 338 + +GN +ID +G + S LD E + Y L ++A Sbjct: 311 IV----SGNEGEAFSIDKVTGDITISKPLDYENGPRVYTLNISA 350 Score = 47.6 bits (108), Expect = 0.005 Identities = 42/153 (27%), Positives = 66/153 (43%), Gaps = 22/153 (14%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND++P F+ S E G TV TL ATD D NA + + I V+ + Sbjct: 260 LTITDINDNAPAFQNTPLTVSCSENRPIGLTVATLTATDADATTNAIITFVI--VSGNE- 316 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSDR 129 + F ID +G + LD E R YT+ + A + + + Sbjct: 317 ----------------GEAFSIDKVTGDITISKPLDYENGPRVYTLNISAMNNHTDL--M 358 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162 L S + +NI D +D FS+K Y +D++ Sbjct: 359 LQSFGVVTINITDVDDLPANFSQKLYEAHIDKN 391 Score = 46.4 bits (105), Expect = 0.011 Identities = 30/104 (28%), Positives = 56/104 (53%), Gaps = 7/104 (6%) Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDK--LQYRILSGNNAN 838 + +TD+NDNAP ++ + + ++ P+G + A DAD T + + I+SGN Sbjct: 260 LTITDINDNAPAFQNTPLTVSCSENR-PIGLTVATLTATDADATTNAIITFVIVSGNEGE 318 Query: 839 LILLNETTGSMTLSPQLN-TNVPKLATMEVSVTDGVNEIKAMMQ 881 +++ TG +T+S L+ N P++ T+ +S + N M+Q Sbjct: 319 AFSIDKVTGDITISKPLDYENGPRVYTLNISAMN--NHTDLMLQ 360 >UniRef50_Q7YWB9 Cluster: Cadherin-like protein cad2; n=1; Aplysia californica|Rep: Cadherin-like protein cad2 - Aplysia californica (California sea hare) Length = 736 Score = 303 bits (745), Expect = 3e-80 Identities = 243/729 (33%), Positives = 363/729 (49%), Gaps = 54/729 (7%) Query: 86 VQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145 V+ +F ++ SG ++ R SL + + V+A D P L S + + ++ ND Sbjct: 4 VEKLFDVNAYSGEIVPRDSLIDAENQLFQFFVRAADGGEP---SLESHIPVEILVMGRND 60 Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKA-TDADVGANSAIRYAIIGGNTQMQFSIDS 204 + P+F E VDED V +IA IKA + V R+ N F++DS Sbjct: 61 SPPKFLESRRPFFVDEDEQV--GAIIATIKARSSGPVVLQHCTRFHSKCQNKPAIFTVDS 118 Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 L G + L++ LD+E SYRL +RAQ SP+ + ++ I +RDVNDN P F +Q Sbjct: 119 L-GRLRLMRRLDWETTPSYRLFVRAQSRTSPALVDHMEIGIEVRDVNDNPPFFACMPYQA 177 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 +VSE+ + I+++QA D D N L +T+ + +ID +SGW+ +L Sbjct: 178 TVSESAKSQHQIIQLQASDRDLQTNP-LKFTL-GPGMQAMASI-FSIDAKSGWIMLLTKL 234 Query: 325 DRETQAKYQLLVTATD---------GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375 DRETQ++Y L V +D G P + T + F Y + Sbjct: 235 DRETQSQYNLTVVVSDSPSSSLRKSGQYPSLTTTTSVLITVTDCNDNPPAFEKQNYPTAV 294 Query: 376 AEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ 433 E PGT ++TL TDAD ++ + Y IT G+ GRF I S G + V +PLD + Sbjct: 295 NEGALPGTVLITLDTTDADSGPNSDVTYYITEGDQLGRFEIHST---GELFVNKPLDRET 351 Query: 434 ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV----FENAPYTASVFEDAPIGTTVL 489 + +Y L V+ATD G V +++ D N+ APV F + + PI V Sbjct: 352 KAQYRLRVAATD-GAYVTFTTVTVDVLDDNDNAPVCISRFIKWFRMKTSSKALPIAH-VR 409 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 + D+ +N++++YSL+ E A H F+I+ +TG I T KLLDRET + L Sbjct: 410 GIRDADAPSTVNSRVSYSLTGE-----GADH---FLIDKETGLIRTAKLLDRETQPEFEL 461 Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ----QLYTANIMEDALVGTSVSQVGA 605 T ARDGG LS TT V I + DV DN P F Q +LY+ I EDA + T ++ A Sbjct: 462 TAVARDGG--GLSCTTLVLIYLKDVXDNAPTFTQGTLRKLYS--IHEDAEIHTLXIRLVA 517 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 D D G+N +I Y +D +F I P SG++ AL RE +++L VA + +P Sbjct: 518 IDTDTGINSQIRYRX-ARDXIN-TFSIHPDSGIVSLIAALGRERNPSYNLTVVAYNPISP 575 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 + + + + D+ND+PP F+ I E++ +GT I I A D G NA + YS Sbjct: 576 TSPRKLTIMVTVLDVNDNPPEFQHSSYYATIQESANVGTPIIXITATSLDIGXNADITYS 635 Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA--ASPPLWNDVRVEIL 783 I G++ FS++ +G LV LD+E R+ + V+ +PPL + V I Sbjct: 636 IAAGNEQGKFSIDPNKG----VLVVTEPLDHELAREYFITVLATDRGTPPLTDTAIVSIN 691 Query: 784 VTDVNDNAP 792 +TDVNDN P Sbjct: 692 ITDVNDNPP 700 Score = 280 bits (686), Expect = 5e-73 Identities = 206/648 (31%), Positives = 303/648 (46%), Gaps = 40/648 (6%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +F +D G L LD E Y + V+A + SP L I + + D NDN P Sbjct: 113 IFTVDSL-GRLRLMRRLDWETTPSYRLFVRAQSRTSPA---LVDHMEIGIEVRDVNDNPP 168 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ--FSIDSLS 206 F+ Y +V E S I +++A+D D+ N +++ + G M FSID+ S Sbjct: 169 FFACMPYQATVSE--SAKSQHQIIQLQASDRDLQTNP-LKFTLGPGMQAMASIFSIDAKS 225 Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGS---------PSRSNTTQLLINIRDVNDNAPRF 257 G + L+ LD E Y L + D S PS + TT +LI + D NDN P F Sbjct: 226 GWIMLLTKLDRETQSQYNLTVVVSDSPSSSLRKSGQYPSLTTTTSVLITVTDCNDNPPAF 285 Query: 258 YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317 + +V+E G ++ + DAD G N+++TY +T+ D G ++ T G Sbjct: 286 EKQNYPTAVNEGALPGTVLITLDTTDADSGPNSDVTYYITEGDQLGRFEIHST-----GE 340 Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377 ++ + LDRET+A+Y+L V ATDG + + ++ + Sbjct: 341 LFVNKPLDRETKAQYRLRVAATDGAYVTFTTVTVDVLDDNDNAPVCISRFIKWFRMKTSS 400 Query: 378 DEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435 P V + DA ++R+ Y +TG F I + G LI A+ LD + + Sbjct: 401 KALPIAHVRGIRDADAPSTVNSRVSYSLTGEGA-DHFLIDKETG--LIRTAKLLDRETQP 457 Query: 436 RYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA--SVFEDAPIGTTVLVVSA 493 + LT A D GG S T +V I + D + AP F S+ EDA I T + + A Sbjct: 458 EFELTAVARDGGGLSCTTLVLIYLKDVXDNAPTFTQGTLRKLYSIHEDAEIHTLXIRLVA 517 Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553 D+D GIN+QI Y + + N F I+P +G ++ L RE Y LTV A Sbjct: 518 IDTDTGINSQIRYRXARDXINT--------FSIHPDSGIVSLIAALGRERNPSYNLTVVA 569 Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613 + P+ + ++V+DVNDN P F+ Y A I E A VGT + + AT D+G N Sbjct: 570 YNPISPTSPRKLTIMVTVLDVNDNPPEFQHSSYYATIQESANVGTPIIXITATSLDIGXN 629 Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673 I Y + E+G F IDP GV+ + LD E + + +A D GTPP + T IV Sbjct: 630 ADITYSI-AAGNEQGKFSIDPNKGVLVVTEPLDHELAREYFITVLATDRGTPPLTDTAIV 688 Query: 674 HIKIEDINDSPPVFESDCL-TFYISENSPIGTTIGEIRAHDPDEGPNA 720 I I D+ND+PP F D L ++ N GT I ++ A D D NA Sbjct: 689 SINITDVNDNPPRFSQDALPPVHVKXNVHEGTXIFKVMATDXDSLANA 736 Score = 235 bits (576), Expect = 1e-59 Identities = 184/616 (29%), Positives = 295/616 (47%), Gaps = 59/616 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+ P F Y+A+V E A S ++ L+A+D+D+ N +++ TL Sbjct: 158 IEVRDVNDNPPFFACMPYQATVSESAKSQHQIIQLQASDRDLQTN-PLKF--------TL 208 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR- 129 P + +F ID +SG ++ LDRE ++Y + V +D S + Sbjct: 209 GP---------GMQAMASIFSIDAKSGWIMLLTKLDRETQSQYNLTVVVSDSPSSSLRKS 259 Query: 130 -----LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184 L++T ++ + + D NDN P F ++ Y +V+E V+ + TDAD G N Sbjct: 260 GQYPSLTTTTSVLITVTDCNDNPPAFEKQNYPTAVNE--GALPGTVLITLDTTDADSGPN 317 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 S + Y I G+ +F I S +G++ + K LD E YRL + A DG + + T Sbjct: 318 SDVTYYITEGDQLGRFEIHS-TGELFVNKPLDRETKAQYRLRVAATDGAYVTFTTVT--- 373 Query: 245 INIRDVNDNAP----RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 +++ D NDNAP RF ++ S+ +PI + + ++ DA VN+ ++Y++ Sbjct: 374 VDVLDDNDNAPVCISRFIKWFRMKTSSKALPIAH-VRGIRDADAPSTVNSRVSYSL---- 428 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 TG ID +G + T+ LDRETQ +++L A DGG S T Sbjct: 429 -TGEGADHFLIDKETGLIRTAKLLDRETQPEFELTAVARDGGG--LSCTTLVLIYLKDVX 485 Query: 361 XXXXXFMPGQYE--VELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITS 416 F G + ED T + L A D D ++++ Y + FSI Sbjct: 486 DNAPTFTQGTLRKLYSIHEDAEIHTLXIRLVAIDTDTGINSQIRYR-XARDXINTFSIHP 544 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATD--SGGRSDTAMVQINITDANNYAPVFENAPY 474 + G++++ L ++ Y LTV A + S + + + D N+ P F+++ Y Sbjct: 545 DS--GIVSLIAALGRERNPSYNLTVVAYNPISPTSPRKLTIMVTVLDVNDNPPEFQHSSY 602 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 A++ E A +GT ++ ++AT D+G NA ITYS+ A + +F I+P G + Sbjct: 603 YATIQESANVGTPIIXITATSLDIGXNADITYSI-------AAGNEQGKFSIDPNKGVLV 655 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ-LYTANIMED 593 + LD E Y +TV A D G P L+DT V I++ DVNDN P F Q L ++ + Sbjct: 656 VTEPLDHELAREYFITVLATDRGTPPLTDTAIVSINITDVNDNPPRFSQDALPPVHVKXN 715 Query: 594 ALVGTSVSQVGATDAD 609 GT + +V ATD D Sbjct: 716 VHEGTXIFKVMATDXD 731 Score = 206 bits (503), Expect = 7e-51 Identities = 164/500 (32%), Positives = 225/500 (45%), Gaps = 44/500 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V DCND+ P FE Q Y +V EGA GT ++TL TD D G N++V Y I D L Sbjct: 273 ITVTDCNDNPPAFEKQNYPTAVNEGALPGTVLITLDTTDADSGPNSDVTYYI--TEGDQL 330 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F I +G L LDRE A+Y + V ATD A Sbjct: 331 GR-----------------FEIHS-TGELFVNKPLDRETKAQYRLRVAATDGA------Y 366 Query: 131 SSTATIHVNIIDDNDNYPQ-FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + T+ V+++DDNDN P S + + I+ DA NS + Y Sbjct: 367 VTFTTVTVDVLDDNDNAPVCISRFIKWFRMKTSSKALPIAHVRGIRDADAPSTVNSRVSY 426 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 ++ G F ID +G + K LD E + L A+DGG S TT +LI ++D Sbjct: 427 SLTGEGAD-HFLIDKETGLIRTAKLLDRETQPEFELTAVARDGG--GLSCTTLVLIYLKD 483 Query: 250 VNDNAPRFYTSLFQE--SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 V DNAP F ++ S+ E+ I +R+ A D D G+N+++ Y +D Sbjct: 484 VXDNAPTFTQGTLRKLYSIHEDAEIHTLXIRLVAIDTDTGINSQIRYRXA-RDXINT--- 539 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 +I P SG V L RE Y L V A + P T F Sbjct: 540 -FSIHPDSGIVSLIAALGRERNPSYNLTVVAYNPISPTSPRKLTIMVTVLDVNDNPPEFQ 598 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITV 425 Y + E GTP++ +TAT D + + Y I GN +G+FSI +G++ V Sbjct: 599 HSSYYATIQESANVGTPIIXITATSLDIGXNADITYSIAAGNEQGKFSI--DPNKGVLVV 656 Query: 426 AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVF-ENAPYTASVFEDA 482 +PLD + R Y +TV ATD G +DTA+V INITD N+ P F ++A V + Sbjct: 657 TEPLDHELAREYFITVLATDRGTPPLTDTAIVSINITDVNDNPPRFSQDALPPVHVKXNV 716 Query: 483 PIGTTVLVVSATDSDVGINA 502 GT + V ATD D NA Sbjct: 717 HEGTXIFKVMATDXDSLANA 736 Score = 127 bits (306), Expect = 5e-27 Identities = 126/448 (28%), Positives = 185/448 (41%), Gaps = 30/448 (6%) Query: 441 VSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498 V A D G S V+I + N+ P F + V ED +G + + A S Sbjct: 35 VRAADGGEPSLESHIPVEILVMGRNDSPPKFLESRRPFFVDEDEQVGAIIATIKARSSGP 94 Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558 + T S+ N+ F ++ G + + LD ET Y L V A+ Sbjct: 95 VVLQHCT-RFHSKCQNKPAI-----FTVD-SLGRLRLMRRLDWETTPSYRLFVRAQSRTS 147 Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618 P+L D ++ I V DVNDN P F Y A + E A + Q+ A+D D+ N + + Sbjct: 148 PALVDHMEIGIEVRDVNDNPPFFACMPYQATVSESAKSQHQIIQLQASDRDLQTNP-LKF 206 Query: 619 ELDPKDREEGS-FVIDPASGVIRTNKALDRESVATHDLKAVAID---------GGTPPQS 668 L P + S F ID SG I LDRE+ + ++L V D G P + Sbjct: 207 TLGPGMQAMASIFSIDAKSGWIMLLTKLDRETQSQYNLTVVVSDSPSSSLRKSGQYPSLT 266 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 +T V I + D ND+PP FE ++E + GT + + D D GPN+ V Y I Sbjct: 267 TTTSVLITVTDCNDNPPAFEKQNYPTAVNEGALPGTVLITLDTTDADSGPNSDVTYYITE 326 Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVN 788 GD F + + EL LD E+ + +Y L + A V + V D N Sbjct: 327 GDQLGRFEIHST-----GELFVNKPLDRET-KAQYRLRVAATDGAYVTFTTVTVDVLDDN 380 Query: 789 DNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY-DADVTDKLQYRI---LSGNNANLILLNE 844 DNAPV I + K P V DAD + R+ L+G A+ L+++ Sbjct: 381 DNAPVCISRFIKWFRMKTSSKALPIAHVRGIRDADAPSTVNSRVSYSLTGEGADHFLIDK 440 Query: 845 TTGSMTLSPQLNTNVPKLATMEVSVTDG 872 TG + + L+ + DG Sbjct: 441 ETGLIRTAKLLDRETQPEFELTAVARDG 468 Score = 75.8 bits (178), Expect = 2e-11 Identities = 89/367 (24%), Positives = 157/367 (42%), Gaps = 22/367 (5%) Query: 521 DQQFVINPQTGAITT-NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP 579 ++ F +N +G I + L+D E + V A DGG PSL VEI V+ ND+ P Sbjct: 5 EKLFDVNAYSGEIVPRDSLIDAENQL-FQFFVRAADGGEPSLESHIPVEILVMGRNDSPP 63 Query: 580 VFKQQLYTANIMEDALVGTSVSQVGA-TDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638 F + + ED VG ++ + A + V L + +++ F +D + G Sbjct: 64 KFLESRRPFFVDEDEQVGAIIATIKARSSGPVVLQHCTRFHSKCQNKP-AIFTVD-SLGR 121 Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698 +R + LD E+ ++ L A +P + + I++ D+ND+PP F +SE Sbjct: 122 LRLMRRLDWETTPSYRLFVRAQSRTSPALVDHMEIGIEVRDVNDNPPFFACMPYQATVSE 181 Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS--FSLETRQGSDKAELVTMVDLDY 756 ++ I +++A D D N + +++ G + + FS++ + G L+T +D + Sbjct: 182 SAKSQHQIIQLQASDRDLQTNPL-KFTLGPGMQAMASIFSIDAKSGW--IMLLTKLDRET 238 Query: 757 ESPRKKYELVIRAAS---------PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC 807 +S +V + S P L V I VTD NDN P + + Sbjct: 239 QSQYNLTVVVSDSPSSSLRKSGQYPSLTTTTSVLITVTDCNDNPPAFEKQNYPTAVNEGA 298 Query: 808 FPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATM 865 P + DAD + Y I G+ ++ +TG + ++ L+ + Sbjct: 299 LPGTVLITLDTTDADSGPNSDVTYYITEGDQLGRFEIH-STGELFVNKPLDRETKAQYRL 357 Query: 866 EVSVTDG 872 V+ TDG Sbjct: 358 RVAATDG 364 >UniRef50_Q7PTV6 Cluster: ENSANGP00000002131; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000002131 - Anopheles gambiae str. PEST Length = 603 Score = 303 bits (745), Expect = 3e-80 Identities = 217/617 (35%), Positives = 312/617 (50%), Gaps = 36/617 (5%) Query: 142 DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFS 201 D NDN P F+ + Y VSV E S + PVI ++K TD D G N+ + I+GGN +F Sbjct: 1 DINDNAPVFNREIYEVSVPET-SPPNTPVI-RLKVTDRDEGKNAKVFLEIVGGNEGGEFR 58 Query: 202 IDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS--RSNTTQLLINIRDVNDNAPRFYT 259 ++ +G + LD E Y L + A D G+P + ++ ++ IN++D NDN P F T Sbjct: 59 VNPETGMLYTAVPLDAELKAFYTLTVSAIDQGNPGTRKQSSAKVKINVQDTNDNDPIFET 118 Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319 + V EN P G S+ +V A D D G NA ++Y++ + + D+P ID SG V Sbjct: 119 ANLTIYVDENEPAGTSVTKVTARDKDLGENAYISYSIANLN-----DVPFDIDHFSGTVR 173 Query: 320 TSGQLDRET-QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX-XFMPGQYEVELAE 377 TS LD E+ + +Y L V A+D G P R T F + Sbjct: 174 TSKLLDYESMRREYVLRVRASDWGLPYRRQTEMQLVIKLRDVNDNRPQFERIDCLGRIPR 233 Query: 378 DEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG-------RGLITVAQPLD 430 P GT + TL+A D D + + Y + G G F++ S G + + LD Sbjct: 234 YTPIGTEIFTLSALDFDYGSVVTYRLLSGFEDGCFNLDSVTGIISVGCDLNDLKIIGYLD 293 Query: 431 FKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 +++ Y+L ++ D G +S + ++ + I D N+ P FE + + V E+A GT + Sbjct: 294 RERQDEYLLNITVYDLGKPQKSISKILPLTILDENDNVPKFEKSLASFRVTENAINGTII 353 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 V ATD+D+G NA+ITYSL ++ + F ++P+TG +T LDRE Y Sbjct: 354 FRVKATDADLGQNAKITYSLVTD---------TKDFRVDPETGVLTVVAPLDRERQEVYE 404 Query: 549 LTVTARDGG----VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 L + A DGG P+L V ++V D+NDN P F Q T I ED GT V+ V Sbjct: 405 LKIRATDGGGDQNTPALYSDALVRVTVDDINDNAPEFAVQDLTVRIREDVPRGTVVTVVS 464 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 A D D G + I Y EGSF ID SG IRT + LD E H L AID GT Sbjct: 465 AIDLDSGTSSEIVYSFGENGDGEGSFRIDKQSGTIRTARMLDFEERQVHSLIVKAIDRGT 524 Query: 665 PPQSSTVIVHIKIEDINDS--PPVFESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAV 721 P SS V +++ D+N++ P FE LT I+EN P G + ++ A D D GP++ Sbjct: 525 PSLSSETSVIVEVIDVNENRFAPQFEDYVLTGAIAENKPPGAQVMQVLAKDADLPGPDSR 584 Query: 722 VHYSIKGGDDSNSFSLE 738 V YSIKGGD F+++ Sbjct: 585 VTYSIKGGDGLGIFTID 601 Score = 285 bits (700), Expect = 9e-75 Identities = 221/637 (34%), Positives = 312/637 (48%), Gaps = 54/637 (8%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 D ND++PVF + YE SV E + T V+ LK TD+D GKNA+V +E+V + Sbjct: 1 DINDNAPVFNREIYEVSVPETSPPNTPVIRLKVTDRDEGKNAKV--FLEIVGGNEGGE-- 56 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134 FR++ +G L T LD E A YT+ V A DQ +P R S+A Sbjct: 57 ---------------FRVNPETGMLYTAVPLDAELKAFYTLTVSAIDQGNP-GTRKQSSA 100 Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194 + +N+ D NDN P F T+ VDE+ + + K+ A D D+G N+ I Y+I Sbjct: 101 KVKINVQDTNDNDPIFETANLTIYVDENEPAGTS--VTKVTARDKDLGENAYISYSIANL 158 Query: 195 NTQMQFSIDSLSGDVSLVKTLDYEQV-RSYRLVIRAQDGGSPSRSNT-TQLLINIRDVND 252 N + F ID SG V K LDYE + R Y L +RA D G P R T QL+I +RDVND Sbjct: 159 N-DVPFDIDHFSGTVRTSKLLDYESMRREYVLRVRASDWGLPYRRQTEMQLVIKLRDVND 217 Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD--KDYTGNVDLP-- 308 N P+F + PIG I + A D D G + +TY + +D N+D Sbjct: 218 NRPQFERIDCLGRIPRYTPIGTEIFTLSALDFDYG--SVVTYRLLSGFEDGCFNLDSVTG 275 Query: 309 -ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 I++ + G LDRE Q +Y L +T D G P +S + F Sbjct: 276 IISVGCDLNDLKIIGYLDRERQDEYLLNITVYDLGKPQKSISKILPLTILDENDNVPKFE 335 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITV 425 + E+ GT + + ATDAD ++ ++ Y + +T+ F + + G++TV Sbjct: 336 KSLASFRVTENAINGTIIFRVKATDADLGQNAKITYSLV-TDTKD-FRVDPET--GVLTV 391 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDT------AMVQINITDANNYAPVFENAPYTASVF 479 PLD +++ Y L + ATD GG +T A+V++ + D N+ AP F T + Sbjct: 392 VAPLDRERQEVYELKIRATDGGGDQNTPALYSDALVRVTVDDINDNAPEFAVQDLTVRIR 451 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 ED P GT V VVSA D D G +++I YS E F I+ Q+G I T ++L Sbjct: 452 EDVPRGTVVTVVSAIDLDSGTSSEIVYSFGENGDGEG------SFRIDKQSGTIRTARML 505 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE--PVFKQQLYTANIMEDALVG 597 D E + L V A D G PSLS T V + V+DVN+N P F+ + T I E+ G Sbjct: 506 DFEERQVHSLIVKAIDRGTPSLSSETSVIVEVIDVNENRFAPQFEDYVLTGAIAENKPPG 565 Query: 598 TSVSQVGATDADV-GLNGRIHYELDPKDREEGSFVID 633 V QV A DAD+ G + R+ Y + D G F ID Sbjct: 566 AQVMQVLAKDADLPGPDSRVTYSIKGGD-GLGIFTID 601 Score = 250 bits (613), Expect = 3e-64 Identities = 194/620 (31%), Positives = 305/620 (49%), Gaps = 44/620 (7%) Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D+NDNAP F +++ SV E P ++R++ D DEG NA++ + GN Sbjct: 1 DINDNAPVFNREIYEVSVPETSPPNTPVIRLKVTDRDEGKNAKVFLEIVG----GNEGGE 56 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXXXXF 366 ++P +G +YT+ LD E +A Y L V+A D G+P + ++A F Sbjct: 57 FRVNPETGMLYTAVPLDAELKAFYTLTVSAIDQGNPGTRKQSSAKVKINVQDTNDNDPIF 116 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLIT 424 + + E+EP GT V +TA D D E+ + Y I N F I + G + Sbjct: 117 ETANLTIYVDENEPAGTSVTKVTARDKDLGENAYISYSIANLNDVP-FDI--DHFSGTVR 173 Query: 425 VAQPLDFKQERR-YVLTVSATDSG--GRSDTAM-VQINITDANNYAPVFENAPYTASVFE 480 ++ LD++ RR YVL V A+D G R T M + I + D N+ P FE + Sbjct: 174 TSKLLDYESMRREYVLRVRASDWGLPYRRQTEMQLVIKLRDVNDNRPQFERIDCLGRIPR 233 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP--QTGAITTNKL 538 PIGT + +SA D D G + +TY L S + +I+ + Sbjct: 234 YTPIGTEIFTLSALDFDYG--SVVTYRLLSGFEDGCFNLDSVTGIISVGCDLNDLKIIGY 291 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 LDRE YLL +T D G P S + + ++++D NDN P F++ L + + E+A+ GT Sbjct: 292 LDRERQDEYLLNITVYDLGKPQKSISKILPLTILDENDNVPKFEKSLASFRVTENAINGT 351 Query: 599 SVSQVGATDADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 + +V ATDAD+G N +I Y L D KD F +DP +GV+ LDRE ++LK Sbjct: 352 IIFRVKATDADLGQNAKITYSLVTDTKD-----FRVDPETGVLTVVAPLDRERQEVYELK 406 Query: 657 AVAIDGG----TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 A DGG TP S +V + ++DIND+ P F LT I E+ P GT + + A Sbjct: 407 IRATDGGGDQNTPALYSDALVRVTVDDINDNAPEFAVQDLTVRIREDVPRGTVVTVVSAI 466 Query: 713 DPDEGPNAVVHYSI-KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA-- 769 D D G ++ + YS + GD SF ++ + G+ + + LD+E R+ + L+++A Sbjct: 467 DLDSGTSSEIVYSFGENGDGEGSFRIDKQSGTIRTARM----LDFEE-RQVHSLIVKAID 521 Query: 770 -ASPPLWNDVRVEILVTDVNDN--APVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--- 823 +P L ++ V + V DVN+N AP +D+ + ++ P +V A DAD+ Sbjct: 522 RGTPSLSSETSVIVEVIDVNENRFAPQFEDYVLTGAIAENKPPGAQVMQVLAKDADLPGP 581 Query: 824 TDKLQYRILSGNNANLILLN 843 ++ Y I G+ + ++ Sbjct: 582 DSRVTYSIKGGDGLGIFTID 601 Score = 194 bits (474), Expect = 2e-47 Identities = 163/521 (31%), Positives = 243/521 (46%), Gaps = 56/521 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +INV D ND+ P+FE V E +GT+V + A D+D+G+NA + Y+I Sbjct: 103 KINVQDTNDNDPIFETANLTIYVDENEPAGTSVTKVTARDKDLGENAYISYSI------- 155 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSD 128 N D F ID SG + T LD E + R Y + V+A+D P Sbjct: 156 ANLNDV-------------PFDIDHFSGTVRTSKLLDYESMRREYVLRVRASDWGLPY-- 200 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 R + + + + D NDN PQF + + I + A D D G S + Sbjct: 201 RRQTEMQLVIKLRDVNDNRPQFERIDCLGRIPRYTPI--GTEIFTLSALDFDYG--SVVT 256 Query: 189 YAIIGGNTQMQFSIDSLSG---------DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239 Y ++ G F++DS++G D+ ++ LD E+ Y L I D G P +S Sbjct: 257 YRLLSGFEDGCFNLDSVTGIISVGCDLNDLKIIGYLDRERQDEYLLNITVYDLGKPQKSI 316 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 + L + I D NDN P+F SL V+EN G I RV+A DAD G NA++TY++ Sbjct: 317 SKILPLTILDENDNVPKFEKSLASFRVTENAINGTIIFRVKATDADLGQNAKITYSLV-- 374 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG----DPPRSATATXXXX 355 T D +DP +G + LDRE Q Y+L + ATDGG P + A Sbjct: 375 --TDTKD--FRVDPETGVLTVVAPLDRERQEVYELKIRATDGGGDQNTPALYSDALVRVT 430 Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI-TGGNTRGRF 412 F V + ED P GT V ++A D D + + Y G+ G F Sbjct: 431 VDDINDNAPEFAVQDLTVRIREDVPRGTVVTVVSAIDLDSGTSSEIVYSFGENGDGEGSF 490 Query: 413 SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS----DTAMVQINITDANNYAPV 468 I Q+ G I A+ LDF++ + + L V A D G S + +V++ + N +AP Sbjct: 491 RIDKQS--GTIRTARMLDFEERQVHSLIVKAIDRGTPSLSSETSVIVEVIDVNENRFAPQ 548 Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDV-GINAQITYSL 508 FE+ T ++ E+ P G V+ V A D+D+ G ++++TYS+ Sbjct: 549 FEDYVLTGAIAENKPPGAQVMQVLAKDADLPGPDSRVTYSI 589 Score = 155 bits (377), Expect = 1e-35 Identities = 120/416 (28%), Positives = 195/416 (46%), Gaps = 31/416 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D ND+ P FE + GT + TL A D D G + V Y + D Sbjct: 210 IKLRDVNDNRPQFERIDCLGRIPRYTPIGTEIFTLSALDFDYG--SVVTYRLLSGFEDGC 267 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 D+ + D+ +I G LDRE+ Y + + D P + Sbjct: 268 FNLDSVTGIISVGCDLNDL-KIIGY---------LDRERQDEYLLNITVYDLGKP---QK 314 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S + + + I+D+NDN P+F + + V E+ + +I ++KATDAD+G N+ I Y+ Sbjct: 315 SISKILPLTILDENDNVPKFEKSLASFRVTEN--AINGTIIFRVKATDADLGQNAKITYS 372 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG----SPSRSNTTQLLIN 246 ++ F +D +G +++V LD E+ Y L IRA DGG +P+ + + + Sbjct: 373 LV--TDTKDFRVDPETGVLTVVAPLDRERQEVYELKIRATDGGGDQNTPALYSDALVRVT 430 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + D+NDNAP F + E+VP G + V A D D G ++E+ Y+ + G+ + Sbjct: 431 VDDINDNAPEFAVQDLTVRIREDVPRGTVVTVVSAIDLDSGTSSEIVYSFGEN---GDGE 487 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 ID +SG + T+ LD E + + L+V A D G P S+ + Sbjct: 488 GSFRIDKQSGTIRTARMLDFEERQVHSLIVKAIDRGTPSLSSETSVIVEVIDVNENRFAP 547 Query: 367 MPGQYEVE--LAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQ 417 Y + +AE++PPG V+ + A DAD D+R+ Y I GG+ G F+I ++ Sbjct: 548 QFEDYVLTGAIAENKPPGAQVMQVLAKDADLPGPDSRVTYSIKGGDGLGIFTIDNE 603 Score = 148 bits (358), Expect = 3e-33 Identities = 95/291 (32%), Positives = 151/291 (51%), Gaps = 14/291 (4%) Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632 D+NDN PVF +++Y ++ E + T V ++ TD D G N ++ E+ E G F + Sbjct: 1 DINDNAPVFNREIYEVSVPETSPPNTPVIRLKVTDRDEGKNAKVFLEI-VGGNEGGEFRV 59 Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPP--QSSTVIVHIKIEDINDSPPVFESD 690 +P +G++ T LD E A + L AID G P + S+ V I ++D ND+ P+FE+ Sbjct: 60 NPETGMLYTAVPLDAELKAFYTLTVSAIDQGNPGTRKQSSAKVKINVQDTNDNDPIFETA 119 Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750 LT Y+ EN P GT++ ++ A D D G NA + YSI +D F ++ G+ + + Sbjct: 120 NLTIYVDENEPAGTSVTKVTARDKDLGENAYISYSIANLNDV-PFDIDHFSGTVRTSKL- 177 Query: 751 MVDLDYESPRKKYELVIRAASPPL----WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKD 806 LDYES R++Y L +RA+ L ++++ I + DVNDN P + + Sbjct: 178 ---LDYESMRREYVLRVRASDWGLPYRRQTEMQLVIKLRDVNDNRPQFERIDCL-GRIPR 233 Query: 807 CFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 P+G + A D D + YR+LSG L+ TG +++ LN Sbjct: 234 YTPIGTEIFTLSALDFDYGSVVTYRLLSGFEDGCFNLDSVTGIISVGCDLN 284 >UniRef50_Q4SYV0 Cluster: Chromosome undetermined SCAF11948, whole genome shotgun sequence; n=2; Euteleostomi|Rep: Chromosome undetermined SCAF11948, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 3085 Score = 296 bits (726), Expect = 6e-78 Identities = 266/910 (29%), Positives = 406/910 (44%), Gaps = 74/910 (8%) Query: 2 SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 S+P + + N PVF+ Y SV E + T VL + AT K + YT Sbjct: 2211 SIPLSSTTEFPITVVNKAMPVFDKPFYSISVNEDVAVHTPVLGINATSP---KGQSIIYT 2267 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121 I V D +Q F I +G + LD E ARY + V+ATD Sbjct: 2268 I--VDGDP---------------SLQ--FDIGFDTGVIAVIHPLDHETAARYNLTVRATD 2308 Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181 + + + V + D NDN P F + Y V + E + + P + + ATD D Sbjct: 2309 CLTGAHAEVD----VDVAVKDVNDNQPLFKKMAYQVVLSETVMI-GTPAL-HVSATDKDS 2362 Query: 182 GANSAIRYAIIGG-NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240 N+ I Y I N F IDS SG + + LD+E V+ + V+ A D G P S+ Sbjct: 2363 DKNNVIHYQIFSDHNNTDYFHIDSSSGLILTARMLDHELVQKFDFVVIATDNGFPPLSSE 2422 Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 + + + D+NDN P F L++ V E P G+ + VQA DAD +L Y++ Sbjct: 2423 VSVTVMVSDINDNPPVFNQLLYEAYVDELAPRGHFVTCVQASDADSSDYEKLEYSIL--- 2479 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 +GN L +D +G V S + + + Y L ++ +DG ++TA Sbjct: 2480 -SGNEKLVFMLDKMTGIVTLSSRYKQRMEPAYSLNISVSDG---VFTSTAQVHIKVSQGN 2535 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQN 418 F YE ++ E+ GT VV + ATD+D R+ Y R RFSI + Sbjct: 2536 LYAPVFEQNVYEAQVKENSVVGTRVVQVKATDSDPGVFGRVTYSFVNDVGRERFSI---D 2592 Query: 419 GRGLITVAQPLDFKQ-ERRYVL-TVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA 476 G IT A+ LD + +YV+ +V+A D+GG A VQ+++ D N+ AP F Y A Sbjct: 2593 ANGQITTAEKLDREDPSNQYVVVSVAAQDAGGHVSYATVQVSLVDENDNAPHFWATEYRA 2652 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 SV G + V A+D D G NA+ITYS+ S+ S+ V I+P G I T Sbjct: 2653 SVRSSVAEGFLLTQVQASDPDAGTNARITYSIYSD-SHVPVT---DILEIDPDNGWIVTK 2708 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 S V A DGG P+ V + V+ + P F QQ Y ++ ED V Sbjct: 2709 GAFGHLMNSVLYFFVKAEDGGHPARHSLVSVYVHVLSPAASIPSFLQQHYEFSVAEDTSV 2768 Query: 597 GTSVSQVGATD----ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652 GT+V + A + + K ++G FV++ +G+IR NK LD E + Sbjct: 2769 GTAVGMLRLKTPPGYASLSAVFSLVNGAMEKYNQDGVFVVEKDTGLIRLNKPLDHELIKE 2828 Query: 653 HDLKAVA-IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711 + KA A + ++V V +K+ D ND+ P F ++ + E P+ T I ++RA Sbjct: 2829 YYFKATATVQQAKLDSVASVDVQVKVLDRNDNKPEFVTESFEAAVMEGVPLATRILQVRA 2888 Query: 712 HDPDEGPNAVVHYSIKGGDDS--------NSFSLETRQGSDKAELVTMVDLDYESPRKKY 763 D D G N V YS+ G S N+FS++++ G + T+ +LD+E+ Sbjct: 2889 LDADSGANGQVRYSLGGLIQSESQQETLFNTFSIDSQSG----WISTLTNLDHETSSSYV 2944 Query: 764 ELVIRAASPPLWN---DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAY 819 V+ + + + V ++VTDVNDN P + Q F + ++ P G + Sbjct: 2945 FTVVASDFGEITSFSATATVTVVVTDVNDNPPRFLE-QRYFGSVQEGSPPGEVVAALDTR 3003 Query: 820 DAD--VTDK-LQYRILSGNNANLILLNETTGSMTL--SPQLNTNVPKLATMEVSVTDGVN 874 D D T++ + Y I GN L G L +L+ L + VS +DG+ Sbjct: 3004 DNDGSATNRHVSYHITGGNYRGSFALGLVQGEWKLYVKFRLDREERSLYRINVSASDGLF 3063 Query: 875 EIKAMMQLSV 884 ++ +SV Sbjct: 3064 VCHTLVHVSV 3073 Score = 278 bits (682), Expect = 1e-72 Identities = 239/795 (30%), Positives = 368/795 (46%), Gaps = 61/795 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ V D ND+ PVF Y A+V+ A GT + + A DQD G N V Y + Sbjct: 2117 KVQVEDVNDNVPVFVGLPYYAAVQVDAEPGTAIFRVMAIDQDKGINGHVSYYL------- 2169 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDRE-KVARYTVLVKATDQASPVSD 128 +D F I+ +G L + + + + Y +++ A D S Sbjct: 2170 --LDD------------HGHFEINKLTGILSLKKAFESDLSNVEYQMVIYARDHG---SI 2212 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 LSST + ++ N P F + Y++SV+ED++V PV+ I AT +I Sbjct: 2213 PLSSTTEFPITVV--NKAMPVFDKPFYSISVNEDVAV-HTPVLG-INATSP---KGQSII 2265 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y I+ G+ +QF I +G ++++ LD+E Y L +RA D + + + + + ++ Sbjct: 2266 YTIVDGDPSLQFDIGFDTGVIAVIHPLDHETAARYNLTVRATDCLTGAHAE-VDVDVAVK 2324 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 DVNDN P F +Q +SE V IG + V A D D N + Y + D+ N D Sbjct: 2325 DVNDNQPLFKKMAYQVVLSETVMIGTPALHVSATDKDSDKNNVIHYQIF-SDH-NNTDY- 2381 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 ID SG + T+ LD E K+ +V ATD G PP S+ + F Sbjct: 2382 FHIDSSSGLILTARMLDHELVQKFDFVVIATDNGFPPLSSEVSVTVMVSDINDNPPVFNQ 2441 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVA 426 YE + E P G V + A+DAD + +L Y I GN + F + G++T++ Sbjct: 2442 LLYEAYVDELAPRGHFVTCVQASDADSSDYEKLEYSILSGNEKLVFMLDKMT--GIVTLS 2499 Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 + E Y L +S +D G + TA V I ++ N YAPVFE Y A V E++ +GT Sbjct: 2500 SRYKQRMEPAYSLNISVSD-GVFTSTAQVHIKVSQGNLYAPVFEQNVYEAQVKENSVVGT 2558 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 V+ V ATDSD G+ ++TYS +++ E +F I+ G ITT + LDRE S Sbjct: 2559 RVVQVKATDSDPGVFGRVTYSFVNDVGRE-------RFSID-ANGQITTAEKLDREDPSN 2610 Query: 547 --YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 +++V A+D G +S T V++S+VD NDN P F Y A++ G ++QV Sbjct: 2611 QYVVVSVAAQDAG-GHVSYAT-VQVSLVDENDNAPHFWATEYRASVRSSVAEGFLLTQVQ 2668 Query: 605 ATDADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 A+D D G N RI Y + D IDP +G I T A + A DG Sbjct: 2669 ASDPDAGTNARITYSIYSDSHVPVTDILEIDPDNGWIVTKGAFGHLMNSVLYFFVKAEDG 2728 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 G P + S V V++ + S P F F ++E++ +GT +G +R P + Sbjct: 2729 GHPARHSLVSVYVHVLSPAASIPSFLQQHYEFSVAEDTSVGTAVGMLRLKTPPGYASLSA 2788 Query: 723 HYSIKGG--DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY---ELVIRAASPPLWND 777 +S+ G + N + + D + LD+E ++ Y ++ A Sbjct: 2789 VFSLVNGAMEKYNQDGVFVVE-KDTGLIRLNKPLDHELIKEYYFKATATVQQAKLDSVAS 2847 Query: 778 VRVEILVTDVNDNAP 792 V V++ V D NDN P Sbjct: 2848 VDVQVKVLDRNDNKP 2862 Score = 272 bits (666), Expect = 1e-70 Identities = 248/872 (28%), Positives = 381/872 (43%), Gaps = 70/872 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-------LKATDQDIGKNAEVEYTIE 63 I + D ND+ PVF+ +Y S+ E A+ + VL +KATD D +NA + Y I Sbjct: 1803 IQLKDENDNPPVFQQLRYHGSISEAAAVNSVVLNPDDSPLVIKATDADRNENALLVYQIV 1862 Query: 64 LVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQA 123 ED F +D +G++ T ASLD E +A + V D Sbjct: 1863 ---------EDVAKMF----------FAVDSGTGSIRTIASLDHETLAIFHFHVFVRDSG 1903 Query: 124 SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY-TVSVDEDISVTDNPVIAKIKATDADVG 182 P A + + ++D ND+ PQFS+ +Y TV + + + + ++KATD D Sbjct: 1904 RPQLTA-DGPAEVTIQVMDTNDSPPQFSQSSYETVLLRPTYAGVE---VLQVKATDPDED 1959 Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 + + Y++ G + F+I+ LSG + +VK ++ R + +R DG S+T Sbjct: 1960 VSRNLTYSLTNGVLE-HFAIEPLSGTI-VVKQSNFSNER-FLFGVRVSDG---QFSSTAL 2013 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA-DEGVNAELTYTMTDKDY 301 + + +R+ D+ F SL+ ++ EN I +V +A N + YT+ Sbjct: 2014 VNVLVREALDSGLSFSQSLYSSTIQENES---GITQVAVVNALGNQANEPIVYTLL---- 2066 Query: 302 TGNVDLPITIDPRSGWVYTSG-QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 N + I P SG + T+G DRE Q Y+L+V A D R A Sbjct: 2067 --NGGMYFKIRPTSGVIQTTGVAFDREEQESYELVVEARREDDHLRVARVLVKVQVEDVN 2124 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420 F+ Y + D PGT + + A D D+ H + G F I G Sbjct: 2125 DNVPVFVGLPYYAAVQVDAEPGTAIFRVMAIDQDKGINGHVSYYLLDDHGHFEINKLTGI 2184 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 + A D Y + + A D G ++ + IT N PVF+ Y+ SV E Sbjct: 2185 LSLKKAFESDLSNVE-YQMVIYARDHGSIPLSSTTEFPITVVNKAMPVFDKPFYSISVNE 2243 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 D + T VL ++AT I Y++ QF I TG I LD Sbjct: 2244 DVAVHTPVLGINATSPK---GQSIIYTIVD-------GDPSLQFDIGFDTGVIAVIHPLD 2293 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 ET + Y LTV A D + ++ DV+++V DVNDN+P+FK+ Y + E ++GT Sbjct: 2294 HETAARYNLTVRATDCLTGAHAEV-DVDVAVKDVNDNQPLFKKMAYQVVLSETVMIGTPA 2352 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 V ATD D N IHY++ F ID +SG+I T + LD E V D +A Sbjct: 2353 LHVSATDKDSDKNNVIHYQIFSDHNNTDYFHIDSSSGLILTARMLDHELVQKFDFVVIAT 2412 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 D G PP SS V V + + DIND+PPVF Y+ E +P G + ++A D D Sbjct: 2413 DNGFPPLSSEVSVTVMVSDINDNPPVFNQLLYEAYVDELAPRGHFVTCVQASDADSSDYE 2472 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRV 780 + YSI G++ F L+ G +VT+ + Y L I + + +V Sbjct: 2473 KLEYSILSGNEKLVFMLDKMTG-----IVTLSSRYKQRMEPAYSLNISVSDGVFTSTAQV 2527 Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDAD--VTDKLQYRILSGNNA 837 I V+ N APV + + K+ VG +V A D+D V ++ Y ++ Sbjct: 2528 HIKVSQGNLYAPVFEQ-NVYEAQVKENSVVGTRVVQVKATDSDPGVFGRVTYSFVNDVGR 2586 Query: 838 NLILLNETTGSMTLSPQLNTNVPKLATMEVSV 869 + + G +T + +L+ P + VSV Sbjct: 2587 ERFSI-DANGQITTAEKLDREDPSNQYVVVSV 2617 Score = 270 bits (661), Expect = 5e-70 Identities = 248/903 (27%), Positives = 403/903 (44%), Gaps = 84/903 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 Q+ + D ND++P F YE V E GT+VLT+ A D D G+N + Y+I + A Sbjct: 445 QVAIQDANDNTPTFHQSSYEILVNESVPVGTSVLTVSAQDGDDGENGYITYSISSLGA-- 502 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS-----LDREKVARYTVLVKATDQAS 124 P F S + RAS RE T+ VK + Sbjct: 503 -LPFQINQFSGVITTTEPLDFDFSSDSFVFIVRASDWGSPYRRESEVYVTIHVKNVNDNQ 561 Query: 125 PVSDRLSSTATIHVNIIDDND-------NYPQFSEKTYTVSVDEDISV----TDNPVIAK 173 P+ ++ + I ++ D + + + Y + + + D+ V++ Sbjct: 562 PLFEKTACHGVISRDLPADQVITTVSAIDIDELALVKYKIVSGNTLGLFNLNPDSGVLSL 621 Query: 174 IKATDADVGANS-AIRYAIIGGNT---QMQFSIDSLSGDVSLVKTLDYEQVR-SYRL--- 225 ++ V AN+ +++ G M +I + G S K ++ ++ + RL Sbjct: 622 QRSLVPAVSANAFSLKITATDGENLSEPMYVNISVVEGK-SFSKNINCKETMVAQRLAEK 680 Query: 226 VIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE-SVSENVPIGYSIVRVQAYDA 284 +++ G + +S + I+I +N P+F + + +V E++ +G S+ +V AYD Sbjct: 681 LLKKSKGSAAPKSE--EGFIDIFSINRQTPQFSKAFPTDIAVREDLGVGSSVFQVSAYDG 738 Query: 285 DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP 344 D G N ++ Y+++D GN D T+D +G + LDRE + Y L +T D G P Sbjct: 739 DTGFNGQILYSISD----GNPDDCFTMDTDTGLISVLLPLDREKKDHYLLNLTIYDLGRP 794 Query: 345 PRSATATXXXXXXXXXXXXXXFMP-GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEI 403 P+SA F+ G Y V L E+ GT V+ + ATD D Sbjct: 795 PKSAWHLLTVFIEDANDNAPQFLQEGGYTVVLPENTAIGTDVIQVGATDRDAGPNGEVAY 854 Query: 404 TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG----RSDTAMVQINI 459 + F I S +G ++ VA LD + + L V A D R +++ + Sbjct: 855 SLLTATANFGINSTSG--VVYVAGQLDRELVSVFYLKVEARDKAEQGSQRFSVTTLKVVL 912 Query: 460 TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAH 519 D N+ PVF + Y ED P+GT + + D D+G Q+ YSL+++ Sbjct: 913 EDVNDCPPVFIPSVYKTRALEDLPVGTVLAWLETQDPDLGPGGQVQYSLAND-------- 964 Query: 520 HDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDN- 577 ++ F ++ +GAI K LD ET Y L+V A+D G P +L T VE+ VVDVN+N Sbjct: 965 YNGWFEVDRTSGAIRLMKELDYETQQFYNLSVKAKDRGKPVALLSVTSVEVEVVDVNENL 1024 Query: 578 -EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE-GSFVIDPA 635 P F A + E+A +GT++ QV A D DVG +G I Y + +D G F I+ Sbjct: 1025 NAPYFSHFALKATVKENARIGTTLLQVAAQDDDVGRDGEIQYSI--RDGSGLGRFAINEE 1082 Query: 636 SGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695 +GVI T LDRE+ ++ L A D G PQ +T+ V +++ED+ND+ P+ Sbjct: 1083 TGVIYTTDTLDRETKDSYWLTVYATDRGVVPQFATIAVFVQVEDVNDNAPLTSEAMYDSS 1142 Query: 696 ISENSPIGTTIGEIRAHDPDEGPNAV--VHYSIKGGDDSNSFSLETRQG-----SDKAEL 748 + ENSP G ++ +I+A DPDE P + + I G+ N F++ + G S K + Sbjct: 1143 VQENSPEGVSVVQIQAQDPDETPLTAEKLSFHIVSGNPQNLFAINSHTGLITTTSRKLDR 1202 Query: 749 VTMVDLDYESP----------RKKY------ELVIRAASP-PLWNDVRVEILVTDVNDNA 791 + + E+ R + ++++ + P P + V V + V D NDN Sbjct: 1203 EQQTEHNLEASVCVRDAGVWYRASHWSVWPLQVMVSDSGPSPKHSVVWVTVRVLDDNDNK 1262 Query: 792 PVM--KDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTG 847 P+ K +Q+ + P RV AYD D L Y I GN ++ T Sbjct: 1263 PIFPEKVYQVKLAERERRKKAEPIYRVFAYDGDQGPNSDLSYSIADGNEDAKFFIDPKTA 1322 Query: 848 SMT 850 ++ Sbjct: 1323 VLS 1325 Score = 268 bits (657), Expect = 1e-69 Identities = 251/883 (28%), Positives = 406/883 (45%), Gaps = 91/883 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D NDH P+F YE SV E ++ G+ V+ + A D+D G+NA+V+Y+IE Sbjct: 1600 IEVKDVNDHVPIFTRSTYEGSVCESSAVGSAVVQVSALDKDKGENADVQYSIE------- 1652 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F I+ G + L+ + Y + V+ATD+ SP L Sbjct: 1653 ------------SGNKGNTFHIEPILGIITISHDLNLSSIGHYVLTVRATDKGSP---PL 1697 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+T +H+++ ++ P+F ++ Y + E+++V + I + A + + + Y Sbjct: 1698 STTTMVHISVTLSDNAAPKFPQEEYLAVITENVAVGTS--IITVSAV-----SQTTLTYD 1750 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I G+ F I+ SG ++ K LDYE+ SY L+++A + + SN T +I ++D Sbjct: 1751 IKQGDADGVFQINQYSGVITTRKALDYEKTASYSLIVQAVNMAGMA-SNAT-AIIQLKDE 1808 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVR-------VQAYDADEGVNAELTYTMTDKDYTG 303 NDN P F + S+SE + ++ ++A DAD NA L Y + + Sbjct: 1809 NDNPPVFQQLRYHGSISEAAAVNSVVLNPDDSPLVIKATDADRNENALLVYQIVE----D 1864 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA--TATXXXXXXXXXX 361 + +D +G + T LD ET A + V D G P +A A Sbjct: 1865 VAKMFFAVDSGTGSIRTIASLDHETLAIFHFHVFVRDSGRPQLTADGPAEVTIQVMDTND 1924 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNG 419 F YE L G V+ + ATD DED L Y +T G F+I + Sbjct: 1925 SPPQFSQSSYETVLLRPTYAGVEVLQVKATDPDEDVSRNLTYSLTNG-VLEHFAIEPLS- 1982 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479 G I V Q +F E R++ V +D G S TA+V + + +A + F + Y++++ Sbjct: 1983 -GTIVVKQS-NFSNE-RFLFGVRVSD-GQFSSTALVNVLVREALDSGLSFSQSLYSSTIQ 2038 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKL 538 E+ T V VV+A + N I Y+L + F I P +G I TT Sbjct: 2039 ENESGITQVAVVNALGNQA--NEPIVYTL---------LNGGMYFKIRPTSGVIQTTGVA 2087 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 DRE Y L V AR V++ V DVNDN PVF Y A + DA GT Sbjct: 2088 FDREEQESYELVVEARREDDHLRVARVLVKVQVEDVNDNVPVFVGLPYYAAVQVDAEPGT 2147 Query: 599 SVSQVGATDADVGLNGRI-HYELDPKDREEGSFVIDPASGVIRTNKALDRE-SVATHDLK 656 ++ +V A D D G+NG + +Y LD + G F I+ +G++ KA + + S + + Sbjct: 2148 AIFRVMAIDQDKGINGHVSYYLLD----DHGHFEINKLTGILSLKKAFESDLSNVEYQMV 2203 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 A D G+ P SST I + +N + PVF+ + ++E+ + T + I A P + Sbjct: 2204 IYARDHGSIPLSSTTEFPITV--VNKAMPVFDKPFYSISVNEDVAVHTPVLGINATSP-K 2260 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--PPL 774 G + + Y+I GD S F + G D + + LD+E+ +Y L +RA Sbjct: 2261 GQSII--YTIVDGDPSLQFDI----GFDTGVIAVIHPLDHET-AARYNLTVRATDCLTGA 2313 Query: 775 WNDVRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPVG-PFGRVPA--YDADVTDKLQY 829 +V V++ V DVNDN P+ K +Q++ + + +G P V A D+D + + Y Sbjct: 2314 HAEVDVDVAVKDVNDNQPLFKKMAYQVVLS---ETVMIGTPALHVSATDKDSDKNNVIHY 2370 Query: 830 RILSG-NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 +I S NN + ++ ++G + + L+ + + V TD Sbjct: 2371 QIFSDHNNTDYFHIDSSSGLILTARMLDHELVQKFDFVVIATD 2413 Score = 262 bits (643), Expect = 7e-68 Identities = 228/799 (28%), Positives = 344/799 (43%), Gaps = 53/799 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D ND+ P+F+ Y+ + E GT L + ATD+D KN + Y I +D Sbjct: 2321 VAVKDVNDNQPLFKKMAYQVVLSETVMIGTPALHVSATDKDSDKNNVIHYQI---FSDHN 2377 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N D F ID SG +LT LD E V ++ +V ATD P L Sbjct: 2378 NT---------------DYFHIDSSSGLILTARMLDHELVQKFDFVVIATDNGFPP---L 2419 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SS ++ V + D NDN P F++ Y VDE + ++A+DAD + Y+ Sbjct: 2420 SSEVSVTVMVSDINDNPPVFNQLLYEAYVDE--LAPRGHFVTCVQASDADSSDYEKLEYS 2477 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I+ GN ++ F +D ++G V+L +Y L I DG S T Q+ I + Sbjct: 2478 ILSGNEKLVFMLDKMTGIVTLSSRYKQRMEPAYSLNISVSDGVFTS---TAQVHIKVSQG 2534 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 N AP F ++++ V EN +G +V+V+A D+D GV +TY+ + G I Sbjct: 2535 NLYAPVFEQNVYEAQVKENSVVGTRVVQVKATDSDPGVFGRVTYSFVND--VGRERFSID 2592 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 + G + T+ +LDRE + ++V+ + AT F + Sbjct: 2593 AN---GQITTAEKLDREDPSNQYVVVSVAAQDAGGHVSYATVQVSLVDENDNAPHFWATE 2649 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQN-GRGLITVAQ 427 Y + G + + A+D D R+ Y I + I + G I Sbjct: 2650 YRASVRSSVAEGFLLTQVQASDPDAGTNARITYSIYSDSHVPVTDILEIDPDNGWIVTKG 2709 Query: 428 PLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 V A D G R V +++ P F Y SV ED +G Sbjct: 2710 AFGHLMNSVLYFFVKAEDGGHPARHSLVSVYVHVLSPAASIPSFLQQHYEFSVAEDTSVG 2769 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 T V ++ + +SL + + + D FV+ TG I NK LD E + Sbjct: 2770 TAVGMLRLKTPPGYASLSAVFSLVNGAMEKY--NQDGVFVVEKDTGLIRLNKPLDHELIK 2827 Query: 546 GYLL--TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 Y T T + + S++ + DV++ V+D NDN+P F + + A +ME + T + QV Sbjct: 2828 EYYFKATATVQQAKLDSVA-SVDVQVKVLDRNDNKPEFVTESFEAAVMEGVPLATRILQV 2886 Query: 604 GATDADVGLNGRIHYEL----DPKDREE---GSFVIDPASGVIRTNKALDRESVATHDLK 656 A DAD G NG++ Y L + ++E +F ID SG I T LD E+ +++ Sbjct: 2887 RALDADSGANGQVRYSLGGLIQSESQQETLFNTFSIDSQSGWISTLTNLDHETSSSYVFT 2946 Query: 657 AVAIDGGTPPQ-SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 VA D G S+T V + + D+ND+PP F + E SP G + + D D Sbjct: 2947 VVASDFGEITSFSATATVTVVVTDVNDNPPRFLEQRYFGSVQEGSPPGEVVAALDTRDND 3006 Query: 716 -EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL 774 N V Y I GG+ SF+L QG K L LD E R Y + + A+ Sbjct: 3007 GSATNRHVSYHITGGNYRGSFALGLVQGEWK--LYVKFRLDREE-RSLYRINVSASDGLF 3063 Query: 775 WNDVRVEILVTDVNDNAPV 793 V + V D NDN+PV Sbjct: 3064 VCHTLVHVSVLDANDNSPV 3082 Score = 239 bits (584), Expect = 1e-60 Identities = 227/843 (26%), Positives = 361/843 (42%), Gaps = 79/843 (9%) Query: 57 EVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVL 116 E + E+V +L A + VF +D G ++ LD E+ + Y + Sbjct: 1392 ESDKVSEMVGVVSLRRSAATVWFDITGGNSESVFHVDKTVGTIIIAKPLDAEQQSFYNLT 1451 Query: 117 VKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY--TVSVD--EDISVTDNPVIA 172 V+ATD ++ A +HV ++D NDN P FS+ TY TV D D V + Sbjct: 1452 VQATDGTK------AAFAQVHVTVLDTNDNAPIFSQPTYEVTVPEDIPADTEVIQVVAVD 1505 Query: 173 KIKATDADVGANSAI-----RYAIIGGNTQMQFSIDSLSGD----------VSLVKTLDY 217 + + S+I R+ I ++ SL + VSL L Sbjct: 1506 RDRHHQLSYSLQSSIDPSSMRFFHIHPTLGTIHTLQSLDHEACALHILTITVSLKLALFA 1565 Query: 218 EQVRSY-------RLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENV 270 Y + V + +D P R N ++LI ++DVND+ P F S ++ SV E+ Sbjct: 1566 RGFHGYMAVNNKTKTVKKVKDQEFPYRKNMARVLIEVKDVNDHVPIFTRSTYEGSVCESS 1625 Query: 271 PIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA 330 +G ++V+V A D D+G NA++ Y++ +GN I+P G + S L+ + Sbjct: 1626 AVGSAVVQVSALDKDKGENADVQYSIE----SGNKGNTFHIEPILGIITISHDLNLSSIG 1681 Query: 331 KYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTA 390 Y L V ATD G PP S T F +Y + E+ GT ++T++A Sbjct: 1682 HYVLTVRATDKGSPPLSTTTMVHISVTLSDNAAPKFPQEEYLAVITENVAVGTSIITVSA 1741 Query: 391 TDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS 450 L Y+I G+ G F I + G+IT + LD+++ Y L V A + G + Sbjct: 1742 V---SQTTLTYDIKQGDADGVFQINQYS--GVITTRKALDYEKTASYSLIVQAVNMAGMA 1796 Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV-------LVVSATDSDVGINAQ 503 A I + D N+ PVF+ Y S+ E A + + V LV+ ATD+D NA Sbjct: 1797 SNATAIIQLKDENDNPPVFQQLRYHGSISEAAAVNSVVLNPDDSPLVIKATDADRNENAL 1856 Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS- 562 + Y + +++ F ++ TG+I T LD ET++ + V RD G P L+ Sbjct: 1857 LVYQIVEDVAK-------MFFAVDSGTGSIRTIASLDHETLAIFHFHVFVRDSGRPQLTA 1909 Query: 563 -DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621 +V I V+D ND+ P F Q Y ++ G V QV ATD D ++ + Y L Sbjct: 1910 DGPAEVTIQVMDTNDSPPQFSQSSYETVLLRPTYAGVEVLQVKATDPDEDVSRNLTYSLT 1969 Query: 622 PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681 E F I+P SG I + ++S +++ + SST +V++ + + Sbjct: 1970 NGVLEH--FAIEPLSGTI-----VVKQSNFSNERFLFGVRVSDGQFSSTALVNVLVREAL 2022 Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741 DS F + I EN T + + A ++ +V+ + GG F + Sbjct: 2023 DSGLSFSQSLYSSTIQENESGITQVAVVNALG-NQANEPIVYTLLNGG---MYFKIRPTS 2078 Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRAASPP---LWNDVRVEILVTDVNDNAPVMKDFQ 798 G + T V D E ++ YELV+ A V V++ V DVNDN PV Sbjct: 2079 GVIQ---TTGVAFDREE-QESYELVVEARREDDHLRVARVLVKVQVEDVNDNVPVFVGLP 2134 Query: 799 IIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 D P RV A D D + + Y +L + +N+ TG ++L Sbjct: 2135 YYAAVQVDAEPGTAIFRVMAIDQDKGINGHVSYYLLDDHGH--FEINKLTGILSLKKAFE 2192 Query: 857 TNV 859 +++ Sbjct: 2193 SDL 2195 Score = 238 bits (583), Expect = 1e-60 Identities = 246/913 (26%), Positives = 401/913 (43%), Gaps = 105/913 (11%) Query: 11 INVLDCNDHSPVFEMQ-QYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 I++ N +P F + +VRE G++V + A D D G N ++ Y+I +D Sbjct: 698 IDIFSINRQTPQFSKAFPTDIAVREDLGVGSSVFQVSAYDGDTGFNGQILYSI----SDG 753 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 NP+D F +D +G + LDREK Y + + D P Sbjct: 754 -NPDDC--------------FTMDTDTGLISVLLPLDREKKDHYLLNLTIYDLGRPPK-- 796 Query: 130 LSSTATIHVNIIDDNDNYPQF-SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 S+ + V I D NDN PQF E YTV + E+ ++ + + ++ ATD D G N + Sbjct: 797 -SAWHLLTVFIEDANDNAPQFLQEGGYTVVLPENTAIGTD--VIQVGATDRDAGPNGEVA 853 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS--RSNTTQLLIN 246 Y+++ F I+S SG V + LD E V + L + A+D R + T L + Sbjct: 854 YSLLTATAN--FGINSTSGVVYVAGQLDRELVSVFYLKVEARDKAEQGSQRFSVTTLKVV 911 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + DVND P F S+++ E++P+G + ++ D D G ++ Y++ + DY G + Sbjct: 912 LEDVNDCPPVFIPSVYKTRALEDLPVGTVLAWLETQDPDLGPGGQVQYSLAN-DYNGWFE 970 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX- 365 +D SG + +LD ETQ Y L V A D G P + T Sbjct: 971 ----VDRTSGAIRLMKELDYETQQFYNLSVKAKDRGKPVALLSVTSVEVEVVDVNENLNA 1026 Query: 366 --FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRG 421 F + + E+ GT ++ + A D D D + Y I G+ GRF+I + G Sbjct: 1027 PYFSHFALKATVKENARIGTTLLQVAAQDDDVGRDGEIQYSIRDGSGLGRFAINEETG-- 1084 Query: 422 LITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVF 479 +I LD + + Y LTV ATD G + T V + + D N+ AP+ A Y +SV Sbjct: 1085 VIYTTDTLDRETKDSYWLTVYATDRGVVPQFATIAVFVQVEDVNDNAPLTSEAMYDSSVQ 1144 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ-FVINPQTGAITT-NK 537 E++P G +V+ + A D D T + ++S V+ + Q F IN TG ITT ++ Sbjct: 1145 ENSPEGVSVVQIQAQDPDE------TPLTAEKLSFHIVSGNPQNLFAINSHTGLITTTSR 1198 Query: 538 LLDRETMSGYLL--TVTARDGGV-------------PSLSDTTD--------VEISVVDV 574 LDRE + + L +V RD GV +SD+ V + V+D Sbjct: 1199 KLDREQQTEHNLEASVCVRDAGVWYRASHWSVWPLQVMVSDSGPSPKHSVVWVTVRVLDD 1258 Query: 575 NDNEPVFKQQLYTANI--MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632 NDN+P+F +++Y + E + +V A D D G N + Y + E+ F I Sbjct: 1259 NDNKPIFPEKVYQVKLAERERRKKAEPIYRVFAYDGDQGPNSDLSYSI-ADGNEDAKFFI 1317 Query: 633 DPASGVIRTNKALDRESVATHDLKAV----------AIDGGTPPQSSTVIVHIK-IEDIN 681 DP + V+ + KA + T+++ V A D G P +SST +HI+ + Sbjct: 1318 DPKTAVLSSRKAF---AAGTYNILTVCYGFYRTSIKATDNGRPQKSSTARLHIEWVRRPP 1374 Query: 682 DSPP-VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR 740 PP +F+ F + E+ + +G + A V + I GG+ + F ++ Sbjct: 1375 AGPPLLFDQPFYNFTVMESDKVSEMVGVVSL----RRSAATVWFDITGGNSESVFHVDKT 1430 Query: 741 QGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQII 800 G+ ++ LD E + Y L ++A +V + V D NDNAP+ Sbjct: 1431 VGT----IIIAKPLDAEQ-QSFYNLTVQATDGTKAAFAQVHVTVLDTNDNAPIFSQPTYE 1485 Query: 801 FNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSG---NNANLILLNETTGSMTLSPQLNT 857 +D +V A D D +L Y + S ++ ++ T G++ L+ Sbjct: 1486 VTVPEDIPADTEVIQVVAVDRDRHHQLSYSLQSSIDPSSMRFFHIHPTLGTIHTLQSLDH 1545 Query: 858 NVPKLATMEVSVT 870 L + ++V+ Sbjct: 1546 EACALHILTITVS 1558 Score = 231 bits (566), Expect = 2e-58 Identities = 243/850 (28%), Positives = 368/850 (43%), Gaps = 123/850 (14%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 D ND PVF Y+ E GT + L+ D D+G +V+Y++ A+ N Sbjct: 914 DVNDCPPVFIPSVYKTRALEDLPVGTVLAWLETQDPDLGPGGQVQYSL----ANDYN--- 966 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134 F +D SGA+ LD E Y + VKA D+ PV+ L S Sbjct: 967 -------------GWFEVDRTSGAIRLMKELDYETQQFYNLSVKAKDRGKPVA--LLSVT 1011 Query: 135 TIHVNIIDDNDNY--PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192 ++ V ++D N+N P FS +V E+ + + ++ A D DVG + I+Y+I Sbjct: 1012 SVEVEVVDVNENLNAPYFSHFALKATVKENARI--GTTLLQVAAQDDDVGRDGEIQYSIR 1069 Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252 G+ +F+I+ +G + TLD E SY L + A D G + T + + + DVND Sbjct: 1070 DGSGLGRFAINEETGVIYTTDTLDRETKDSYWLTVYATDRGVVPQFATIAVFVQVEDVND 1129 Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG-VNAELTYTMTDKDYTGNVDLPITI 311 NAP +++ SV EN P G S+V++QA D DE + AE ++ +GN I Sbjct: 1130 NAPLTSEAMYDSSVQENSPEGVSVVQIQAQDPDETPLTAE---KLSFHIVSGNPQNLFAI 1186 Query: 312 DPRSGWVYT-SGQLDRETQAKYQL-----------------------LVTATDGGDPPRS 347 + +G + T S +LDRE Q ++ L V +D G P+ Sbjct: 1187 NSHTGLITTTSRKLDREQQTEHNLEASVCVRDAGVWYRASHWSVWPLQVMVSDSGPSPKH 1246 Query: 348 ATATXXXXXXXXXXXXXXFMPGQYEVELAEDE--PPGTPVVTLTATDADE--DNRLHYEI 403 + F Y+V+LAE E P+ + A D D+ ++ L Y I Sbjct: 1247 SVVWVTVRVLDDNDNKPIFPEKVYQVKLAERERRKKAEPIYRVFAYDGDQGPNSDLSYSI 1306 Query: 404 TGGNTRGRFSITSQNG-----RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQ 456 GN +F I + + + Y ++ ATD+G +S TA + Sbjct: 1307 ADGNEDAKFFIDPKTAVLSSRKAFAAGTYNILTVCYGFYRTSIKATDNGRPQKSSTARLH 1366 Query: 457 INITDANNYAP--VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 I P +F+ Y +V E + V VVS S + IT ++ Sbjct: 1367 IEWVRRPPAGPPLLFDQPFYNFTVMESDKVSEMVGVVSLRRSAATVWFDITGG-----NS 1421 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 E+V H D+ G I K LD E S Y LTV A DG + + V ++V+D Sbjct: 1422 ESVFHVDKT------VGTIIIAKPLDAEQQSFYNLTVQATDGTKAAFAQ---VHVTVLDT 1472 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD--VGLNGRIHYELDPKDREEGSFVI 632 NDN P+F Q Y + ED T V QV A D D L+ + +DP F I Sbjct: 1473 NDNAPIFSQPTYEVTVPEDIPADTEVIQVVAVDRDRHHQLSYSLQSSIDPSSMR--FFHI 1530 Query: 633 DPASGVIRTNKALDRESVATHDLKA----------------VAIDGGT-----------P 665 P G I T ++LD E+ A H L +A++ T P Sbjct: 1531 HPTLGTIHTLQSLDHEACALHILTITVSLKLALFARGFHGYMAVNNKTKTVKKVKDQEFP 1590 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 + + V I+++D+ND P+F + E+S +G+ + ++ A D D+G NA V YS Sbjct: 1591 YRKNMARVLIEVKDVNDHVPIFTRSTYEGSVCESSAVGSAVVQVSALDKDKGENADVQYS 1650 Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVIRA---ASPPLWNDVRVE 781 I+ G+ N+F +E G ++T+ DL+ S Y L +RA SPPL V Sbjct: 1651 IESGNKGNTFHIEPILG-----IITISHDLNLSS-IGHYVLTVRATDKGSPPLSTTTMVH 1704 Query: 782 ILVTDVNDNA 791 I VT ++DNA Sbjct: 1705 ISVT-LSDNA 1713 Score = 179 bits (436), Expect = 9e-43 Identities = 141/427 (33%), Positives = 199/427 (46%), Gaps = 28/427 (6%) Query: 457 INITDANNYAPVFENA-PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515 I+I N P F A P +V ED +G++V VSA D D G N QI YS+S Sbjct: 698 IDIFSINRQTPQFSKAFPTDIAVREDLGVGSSVFQVSAYDGDTGFNGQILYSISD----- 752 Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575 + D F ++ TG I+ LDRE YLL +T D G P S + + + D N Sbjct: 753 --GNPDDCFTMDTDTGLISVLLPLDREKKDHYLLNLTIYDLGRPPKSAWHLLTVFIEDAN 810 Query: 576 DNEPVFKQQL-YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634 DN P F Q+ YT + E+ +GT V QVGATD D G NG + Y L +F I+ Sbjct: 811 DNAPQFLQEGGYTVVLPENTAIGTDVIQVGATDRDAGPNGEVAYSLLTAT---ANFGINS 867 Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI--EDINDSPPVFESDCL 692 SGV+ LDRE V+ LK A D + +K+ ED+ND PPVF Sbjct: 868 TSGVVYVAGQLDRELVSVFYLKVEARDKAEQGSQRFSVTTLKVVLEDVNDCPPVFIPSVY 927 Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752 E+ P+GT + + DPD GP V YS+ D + F ++ G+ + M Sbjct: 928 KTRALEDLPVGTVLAWLETQDPDLGPGGQVQYSL-ANDYNGWFEVDRTSGAIRL----MK 982 Query: 753 DLDYESPRKKYELVIRA---ASP-PLWNDVRVEILVTDVNDN--APVMKDFQIIFNNYKD 806 +LDYE+ ++ Y L ++A P L + VE+ V DVN+N AP F + ++ Sbjct: 983 ELDYET-QQFYNLSVKAKDRGKPVALLSVTSVEVEVVDVNENLNAPYFSHFALKATVKEN 1041 Query: 807 CFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLAT 864 +V A D DV ++QY I G+ +NE TG + + L+ Sbjct: 1042 ARIGTTLLQVAAQDDDVGRDGEIQYSIRDGSGLGRFAINEETGVIYTTDTLDRETKDSYW 1101 Query: 865 MEVSVTD 871 + V TD Sbjct: 1102 LTVYATD 1108 Score = 171 bits (416), Expect = 2e-40 Identities = 165/570 (28%), Positives = 257/570 (45%), Gaps = 39/570 (6%) Query: 103 ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162 A L+RE Y + VKA+ + + L + + V ++D ND P FS TY+V++ E Sbjct: 103 AMLNREIQDNYLLTVKASVKGDAL---LETWTKVSVQVLDMNDLRPLFSPTTYSVTIMES 159 Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222 + + IA++ ATDAD+G+N Y + N F++ SG V L L+ ++ Sbjct: 160 TPLRTS--IAQVTATDADIGSNGEFYYFL--KNKMDLFAVHPTSGVVLLSGKLNVDERYQ 215 Query: 223 YRLVIRAQDGG-----SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277 + L I A D G + S+T +L++++ VN++AP N PI Y++V Sbjct: 216 HDLEILAVDRGMKLYGNNGVSSTAKLIVHVERVNEHAPVISVVNSSPWSHANSPI-YAVV 274 Query: 278 RVQAYDADEGVNAEL-TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK-YQLL 335 V+ D D G+N E+ + + D + L + + ++ + L+ ET + L Sbjct: 275 TVE--DPDPGLNGEVDSVVILGGDLSEKFFLERS-EENEFFIRATESLNWETHPRGCNLT 331 Query: 336 VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395 + A D G P + + F Y V L+E PPGT V + E Sbjct: 332 LQAADRGTPQKVSVKVVQIMDEKQSKVAAMFEKEVYNVSLSEFSPPGTVVQVVKIKP--E 389 Query: 396 DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMV 455 + + Y +T F + G +I+ Q + + L V DS + A V Sbjct: 390 SSYVEYTLTPSADSAFFRVNGVTG--VISTTQWFTGVSQSLFKLDVLEMDSELK---AQV 444 Query: 456 QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515 Q+ I DAN+ P F + Y V E P+GT+VL VSA D D G N ITYS+SS + Sbjct: 445 QVAIQDANDNTPTFHQSSYEILVNESVPVGTSVLTVSAQDGDDGENGYITYSISSLGA-- 502 Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMS-GYLLTVTARDGGVPSLSDT-TDVEISVVD 573 F IN +G ITT + LD + S ++ V A D G P ++ V I V + Sbjct: 503 ------LPFQINQFSGVITTTEPLDFDFSSDSFVFIVRASDWGSPYRRESEVYVTIHVKN 556 Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633 VNDN+P+F++ I D ++ V A D D + Y++ G F ++ Sbjct: 557 VNDNQPLFEKTACHGVISRDLPADQVITTVSAIDIDE--LALVKYKI-VSGNTLGLFNLN 613 Query: 634 PASGVIRTNKAL-DRESVATHDLKAVAIDG 662 P SGV+ ++L S LK A DG Sbjct: 614 PDSGVLSLQRSLVPAVSANAFSLKITATDG 643 Score = 139 bits (337), Expect = 9e-31 Identities = 146/608 (24%), Positives = 257/608 (42%), Gaps = 42/608 (6%) Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380 + L+RE Q Y L V A+ GD F P Y V + E P Sbjct: 102 AAMLNREIQDNYLLTVKASVKGDALLETWTKVSVQVLDMNDLRPLFSPTTYSVTIMESTP 161 Query: 381 PGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440 T + +TATDAD + + N F++ +G ++ ++ L+ + ++ L Sbjct: 162 LRTSIAQVTATDADIGSNGEFYYFLKNKMDLFAVHPTSG--VVLLSGKLNVDERYQHDLE 219 Query: 441 VSATDSG-------GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 + A D G G S TA + +++ N +APV + ++PI VV+ Sbjct: 220 ILAVDRGMKLYGNNGVSSTAKLIVHVERVNEHAPVISVVNSSPWSHANSPI---YAVVTV 276 Query: 494 TDSDVGINAQI--TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS-GYLLT 550 D D G+N ++ L ++S + ++ I + L+ ET G LT Sbjct: 277 EDPDPGLNGEVDSVVILGGDLSEKFFLERSEE-----NEFFIRATESLNWETHPRGCNLT 331 Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610 + A D G P V+I + +F++++Y ++ E + GT V V Sbjct: 332 LQAADRGTPQKVSVKVVQIMDEKQSKVAAMFEKEVYNVSLSEFSPPGTVVQVVKIKPE-- 389 Query: 611 GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST 670 + + Y L P + F ++ +GVI T + S + L + +D Q Sbjct: 390 --SSYVEYTLTPS-ADSAFFRVNGVTGVISTTQWFTGVSQSLFKLDVLEMDSELKAQ--- 443 Query: 671 VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD 730 V + I+D ND+ P F ++E+ P+GT++ + A D D+G N + YSI Sbjct: 444 --VQVAIQDANDNTPTFHQSSYEILVNESVPVGTSVLTVSAQDGDDGENGYITYSI---- 497 Query: 731 DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SP-PLWNDVRVEILVTD 786 S+ +L + + T LD++ + ++RA+ SP ++V V I V + Sbjct: 498 -SSLGALPFQINQFSGVITTTEPLDFDFSSDSFVFIVRASDWGSPYRRESEVYVTIHVKN 556 Query: 787 VNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETT 846 VNDN P+ + +D V A D D ++Y+I+SGN L LN + Sbjct: 557 VNDNQPLFEKTACHGVISRDLPADQVITTVSAIDIDELALVKYKIVSGNTLGLFNLNPDS 616 Query: 847 GSMTLSPQLNTNVPKLA-TMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTA 905 G ++L L V A +++++ TDG N + M +++ ++ + +I + M A Sbjct: 617 GVLSLQRSLVPAVSANAFSLKITATDGEN-LSEPMYVNISVVEGKSFSKNINCK-ETMVA 674 Query: 906 EQFLSPLL 913 ++ LL Sbjct: 675 QRLAEKLL 682 Score = 119 bits (286), Expect = 1e-24 Identities = 136/575 (23%), Positives = 244/575 (42%), Gaps = 63/575 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND P+F Y ++ E T++ + ATD DIG N E Y ++ Sbjct: 135 VQVLDMNDLRPLFSPTTYSVTIMESTPLRTSIAQVTATDADIGSNGEFYYFLK------- 187 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV--SD 128 D+F + SG +L L+ ++ ++ + + A D+ + ++ Sbjct: 188 --------------NKMDLFAVHPTSGVVLLSGKLNVDERYQHDLEILAVDRGMKLYGNN 233 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI- 187 +SSTA + V++ N++ P S V S ++P+ A + D D G N + Sbjct: 234 GVSSTAKLIVHVERVNEHAPVIS-----VVNSSPWSHANSPIYAVVTVEDPDPGLNGEVD 288 Query: 188 RYAIIGGNTQMQFSIDSLSGD---VSLVKTLDYE-QVRSYRLVIRAQDGGSPSRSNTTQL 243 I+GG+ +F ++ + + ++L++E R L ++A D G+P + + + Sbjct: 289 SVVILGGDLSEKFFLERSEENEFFIRATESLNWETHPRGCNLTLQAADRGTPQKVSVKVV 348 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 I + A F ++ S+SE P G ++V+V + ++ + YT+T + Sbjct: 349 QIMDEKQSKVAAMFEKEVYNVSLSEFSPPG-TVVQVVKIKPE---SSYVEYTLTPSADSA 404 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 ++ +G + T+ +Q+ ++L V D A Sbjct: 405 F----FRVNGVTGVISTTQWFTGVSQSLFKLDVLEMDS-----ELKAQVQVAIQDANDNT 455 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423 F YE+ + E P GT V+T++A D D D Y ++ G G+I Sbjct: 456 PTFHQSSYEILVNESVPVGTSVLTVSAQDGD-DGENGYITYSISSLGALPFQINQFSGVI 514 Query: 424 TVAQPLDFK-QERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVF 479 T +PLDF +V V A+D G R V I++ + N+ P+FE + Sbjct: 515 TTTEPLDFDFSSDSFVFIVRASDWGSPYRRESEVYVTIHVKNVNDNQPLFEKTACHGVIS 574 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK-L 538 D P + VSA D D A + Y + +S + F +NP +G ++ + L Sbjct: 575 RDLPADQVITTVSAIDIDE--LALVKYKI---VSGNTLG----LFNLNPDSGVLSLQRSL 625 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 + + + + L +TA DG +LS+ V ISVV+ Sbjct: 626 VPAVSANAFSLKITATDG--ENLSEPMYVNISVVE 658 >UniRef50_UPI0000E81ED5 Cluster: PREDICTED: similar to protocadherin beta 20; n=11; Gallus gallus|Rep: PREDICTED: similar to protocadherin beta 20 - Gallus gallus Length = 1166 Score = 295 bits (725), Expect = 9e-78 Identities = 244/839 (29%), Positives = 389/839 (46%), Gaps = 66/839 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V+D ND++P+F Y + E A G+ VL + ATD D+G N ++ Y V + + Sbjct: 159 IIVMDVNDNAPIFTHDIYTGHIAESAPEGSLVLRVMATDADVGTNGDISYQFSQVVSQS- 217 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 Q F I+ +G + + LD E +Y + V+ATD L Sbjct: 218 ----------------QSAFTINTTNGEIRVKTPLDFETTHKYELGVRATDGGG-----L 256 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+ + V ++D NDN P+ +++ + E++ V+A + D D GAN I A Sbjct: 257 SALCKVLVEVMDVNDNAPEIVVSSFSSPIPENVET--GTVVALLAVRDQDSGANGEISCA 314 Query: 191 IIGGNTQMQFSIDSLSG---DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 + Q F++ ++ V TLD E+ + +V+ A D GSP ++T ++I Sbjct: 315 L---EEQPSFALRPAFKNYYELVTVSTLDREERAQHMVVVTAADAGSPPLTSTHTFSVDI 371 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 DVNDNAP F + + V EN + V+A DAD G NA+++Y++ G + Sbjct: 372 SDVNDNAPVFNQTSYTMYVHENNAPALLVGAVKATDADAGPNAKVSYSVVPA--RGPEEE 429 Query: 308 P---ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 P ++++ SG V+ LD E + +++V+A D G PP S++ + Sbjct: 430 PCSCVSVNSESGGVFVLRPLDYEQLRQLEVVVSAADAGSPPLSSSVSVRLLVVDENDNAP 489 Query: 365 XFM-PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423 + P + E G P L A A R+ + GR + G G + Sbjct: 490 LVLHPSAQDSSPPSSETRGWPRRKLLAFRA----RI------ASPAGRQHFRLERGSGRL 539 Query: 424 TVAQPLDFKQERRYVLTVSATDSGGRSDTAM---VQINITDANNYAPVFENAPYTASVFE 480 VA+ LD ++ T + +D +++++ D N+++PVF + T + E Sbjct: 540 VVAERLDREEMCGRSRTCTLAFELLLADPLQFFPIEVSVEDINDHSPVFPDERVTFKIAE 599 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ-QFVINPQTGAITTNKLL 539 G+ V A D DV N YS+ E V++ + + I Q + + L Sbjct: 600 LTEPGSRFPVEGAQDFDVDSNDIQAYSIIPENKFFTVSYEKKNEGDIQVQ---LVLQQPL 656 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 DRE S T+ A DGG P S TT + I V+DVNDN P+F +YT +I E A G+ Sbjct: 657 DREEQSELDFTLVATDGGSPPRSGTTQIHIIVMDVNDNAPIFTHDIYTGHIAESAPEGSL 716 Query: 600 VSQVGATDADVGLNGRIHYELDP-KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 V +V ATDADVG NG I Y+ + + +F I+ +G IR LD E+ ++L Sbjct: 717 VLRVMATDADVGTNGDISYQFSQVVSQSQSAFTINTTNGEIRVKTPLDFETTHKYELGVR 776 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 A DGG S+ V +++ D+ND+ P + I EN GT + + D D G Sbjct: 777 ATDGG--GLSALCKVLVEVMDVNDNAPEIVVSSFSSPIPENVEPGTVVALLAVRDQDSGV 834 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLW 775 N + ++ ++ SF+L + ELVT+ LD E R ++ +V+ AA SPPL Sbjct: 835 NGEITCAL---EEQLSFALRP-AFKNYYELVTVSRLDREE-RAQHMVVVTAADAGSPPLT 889 Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRIL 832 + + ++DVNDNAPV +++ P G V A DAD K+ Y ++ Sbjct: 890 STHTFSVDISDVNDNAPVFNQTSYTMYVHENNAPALLVGAVKATDADAGPNAKVSYSVV 948 Score = 272 bits (667), Expect = 9e-71 Identities = 214/714 (29%), Positives = 334/714 (46%), Gaps = 55/714 (7%) Query: 99 LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158 L+ + LDRE+ + + ATD SP S T IH+ ++D NDN P F+ YT Sbjct: 123 LVLQHPLDREEQSELDFTLVATDGGSPPR---SGTTQIHIIVMDVNDNAPIFTHDIYTGH 179 Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAI--IGGNTQMQFSIDSLSGDVSLVKTLD 216 + E S + ++ ++ ATDADVG N I Y + +Q F+I++ +G++ + LD Sbjct: 180 IAE--SAPEGSLVLRVMATDADVGTNGDISYQFSQVVSQSQSAFTINTTNGEIRVKTPLD 237 Query: 217 YEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSI 276 +E Y L +RA DGG S ++L+ + DVNDNAP S F + ENV G + Sbjct: 238 FETTHKYELGVRATDGG--GLSALCKVLVEVMDVNDNAPEIVVSSFSSPIPENVETGTVV 295 Query: 277 VRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY---TSGQLDRETQAKYQ 333 + D D G N E++ + ++ + P Y T LDRE +A++ Sbjct: 296 ALLAVRDQDSGANGEISCALEEQP-------SFALRPAFKNYYELVTVSTLDREERAQHM 348 Query: 334 LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393 ++VTA D G PP ++T T F Y + + E+ P V + ATDA Sbjct: 349 VVVTAADAGSPPLTSTHTFSVDISDVNDNAPVFNQTSYTMYVHENNAPALLVGAVKATDA 408 Query: 394 D--EDNRLHYEI--TGGNTRGRFSITSQNGR-GLITVAQPLDFKQERRYVLTVSATDSGG 448 D + ++ Y + G S S N G + V +PLD++Q R+ + VSA D+G Sbjct: 409 DAGPNAKVSYSVVPARGPEEEPCSCVSVNSESGGVFVLRPLDYEQLRQLEVVVSAADAGS 468 Query: 449 --RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506 S + V++ + D N+ AP+ + S + +P + G + Sbjct: 469 PPLSSSVSVRLLVVDENDNAPLVLH----PSAQDSSP---------PSSETRGWPRRKLL 515 Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT-ARDGGVPSLSDTT 565 + + I++ A H F + +G + + LDRE M G T T A + + Sbjct: 516 AFRARIASPAGRQH---FRLERGSGRLVVAERLDREEMCGRSRTCTLAFELLLADPLQFF 572 Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625 +E+SV D+ND+ PVF + T I E G+ GA D DV N Y + P+++ Sbjct: 573 PIEVSVEDINDHSPVFPDERVTFKIAELTEPGSRFPVEGAQDFDVDSNDIQAYSIIPENK 632 Query: 626 EEGSFVIDPASGVIRT----NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681 G I+ + LDRE + D VA DGG+PP+S T +HI + D+N Sbjct: 633 FFTVSYEKKNEGDIQVQLVLQQPLDREEQSELDFTLVATDGGSPPRSGTTQIHIIVMDVN 692 Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG--GDDSNSFSLET 739 D+ P+F D T +I+E++P G+ + + A D D G N + Y ++F++ T Sbjct: 693 DNAPIFTHDIYTGHIAESAPEGSLVLRVMATDADVGTNGDISYQFSQVVSQSQSAFTINT 752 Query: 740 RQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAP 792 G E+ LD+E+ KYEL +RA L +V + V DVNDNAP Sbjct: 753 TNG----EIRVKTPLDFETTH-KYELGVRATDGGGLSALCKVLVEVMDVNDNAP 801 Score = 244 bits (596), Expect = 4e-62 Identities = 199/746 (26%), Positives = 333/746 (44%), Gaps = 54/746 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +++ D ND++PVF Y V E + V +KATD D G NA+V Y++ Sbjct: 369 VDISDVNDNAPVFNQTSYTMYVHENNAPALLVGAVKATDADAGPNAKVSYSV----VPAR 424 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 PE+ ++ SG + LD E++ + V+V A D SP L Sbjct: 425 GPEEEPCSCVS----------VNSESGGVFVLRPLDYEQLRQLEVVVSAADAGSPP---L 471 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SS+ ++ + ++D+NDN P + S P K+ A A + + + Sbjct: 472 SSSVSVRLLVVDENDNAPLVLHPSAQDSSPPSSETRGWPR-RKLLAFRARIASPAG---- 526 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDGGSPSRSNTTQLLINIR 248 + F ++ SG + + + LD E++ RS R A + + +++ Sbjct: 527 ------RQHFRLERGSGRLVVAERLDREEMCGRS-RTCTLAFELLLADPLQFFPIEVSVE 579 Query: 249 DVNDNAPRFYTSLFQESVSENVPIG--YSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 D+ND++P F ++E G + + Q +D D + +K +T + + Sbjct: 580 DINDHSPVFPDERVTFKIAELTEPGSRFPVEGAQDFDVDSNDIQAYSIIPENKFFTVSYE 639 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 D + V LDRE Q++ + ATDGG PPRS T F Sbjct: 640 KKNEGDIQVQLVLQQ-PLDREEQSELDFTLVATDGGSPPRSGTTQIHIIVMDVNDNAPIF 698 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLIT 424 Y +AE P G+ V+ + ATDAD + + Y+ + ++ + + T G I Sbjct: 699 THDIYTGHIAESAPEGSLVLRVMATDADVGTNGDISYQFSQVVSQSQSAFTINTTNGEIR 758 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 V PLDF+ +Y L V ATD GG S V + + D N+ AP + +++ + E+ Sbjct: 759 VKTPLDFETTHKYELGVRATDGGGLSALCKVLVEVMDVNDNAPEIVVSSFSSPIPENVEP 818 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 GT V +++ D D G+N +IT +L ++S + + +T ++L DRE Sbjct: 819 GTVVALLAVRDQDSGVNGEITCALEEQLSFALRPAFKNYYEL------VTVSRL-DREER 871 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 + +++ VTA D G P L+ T + + DVNDN PVF Q YT + E+ V V Sbjct: 872 AQHMVVVTAADAGSPPLTSTHTFSVDISDVNDNAPVFNQTSYTMYVHENNAPALLVGAVK 931 Query: 605 ATDADVGLNGRIHYELDP---KDREEGSFV-IDPASGVIRTNKALDRESVATHDLKAVAI 660 ATDAD G N ++ Y + P + E S V ++ SG + + LD E + ++ A Sbjct: 932 ATDADAGPNAKVSYSVVPARGPEEEPCSCVSVNSESGGVFVLRPLDYEQLRQLEVVVSAA 991 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVF-------ESDCLTFYISENSPIGTTIGEIRAHD 713 D G+PP SS+V V + + D ND+ P+ S + + + G + ++ A D Sbjct: 992 DAGSPPLSSSVSVRLLVVDENDNAPLVLHPSAQDSSPPSSELVPAGAEAGDLVSKVVAVD 1051 Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLET 739 D G N+ + Y + + F++ T Sbjct: 1052 ADSGQNSWLSYQLLRATEPGLFAIGT 1077 Score = 220 bits (538), Expect = 4e-55 Identities = 195/672 (29%), Positives = 306/672 (45%), Gaps = 34/672 (5%) Query: 215 LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY 274 LD E+ + A DGGSP RS TTQ+ I + DVNDNAP F ++ ++E+ P G Sbjct: 129 LDREEQSELDFTLVATDGGSPPRSGTTQIHIIVMDVNDNAPIFTHDIYTGHIAESAPEGS 188 Query: 275 SIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQL 334 ++RV A DAD G N +++Y + TI+ +G + LD ET KY+L Sbjct: 189 LVLRVMATDADVGTNGDISYQFS--QVVSQSQSAFTINTTNGEIRVKTPLDFETTHKYEL 246 Query: 335 LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394 V ATDGG SA + + + E+ GT VV L A D Sbjct: 247 GVRATDGGG--LSALCKVLVEVMDVNDNAPEIVVSSFSSPIPENVETGT-VVALLAV-RD 302 Query: 395 EDNRLHYEITGG-NTRGRFSI--TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--R 449 +D+ + EI+ + F++ +N L+TV+ LD ++ ++++ V+A D+G Sbjct: 303 QDSGANGEISCALEEQPSFALRPAFKNYYELVTVS-TLDREERAQHMVVVTAADAGSPPL 361 Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509 + T ++I+D N+ APVF YT V E+ V V ATD+D G NA+++YS+ Sbjct: 362 TSTHTFSVDISDVNDNAPVFNQTSYTMYVHENNAPALLVGAVKATDADAGPNAKVSYSVV 421 Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569 E +N ++G + + LD E + + V+A D G P LS + V + Sbjct: 422 PARGPE--EEPCSCVSVNSESGGVFVLRPLDYEQLRQLEVVVSAADAGSPPLSSSVSVRL 479 Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629 VVD NDN P+ L+ + +D+ +S ++ + RI P R+ Sbjct: 480 LVVDENDNAPLV---LHPS--AQDSSPPSSETRGWPRRKLLAFRARI---ASPAGRQH-- 529 Query: 630 FVIDPASGVIRTNKALDRESVATHDLK-AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688 F ++ SG + + LDRE + +A + + + +EDIND PVF Sbjct: 530 FRLERGSGRLVVAERLDREEMCGRSRTCTLAFELLLADPLQFFPIEVSVEDINDHSPVFP 589 Query: 689 SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR-QGSDKAE 747 + +TF I+E + G+ A D D N + YSI + + S E + +G + + Sbjct: 590 DERVTFKIAELTEPGSRFPVEGAQDFDVDSNDIQAYSIIPENKFFTVSYEKKNEGDIQVQ 649 Query: 748 LVTMVDLDYESPRK-KYELVIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYK 805 LV LD E + + LV SPP ++ I+V DVNDNAP+ I + Sbjct: 650 LVLQQPLDREEQSELDFTLVATDGGSPPRSGTTQIHIIVMDVNDNAPIF-THDIYTGHIA 708 Query: 806 DCFPVGPFG-RVPAYDADVTD----KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVP 860 + P G RV A DADV Q+ + + + +N T G + + L+ Sbjct: 709 ESAPEGSLVLRVMATDADVGTNGDISYQFSQVVSQSQSAFTINTTNGEIRVKTPLDFETT 768 Query: 861 KLATMEVSVTDG 872 + V TDG Sbjct: 769 HKYELGVRATDG 780 Score = 220 bits (538), Expect = 4e-55 Identities = 156/437 (35%), Positives = 218/437 (49%), Gaps = 30/437 (6%) Query: 374 ELAEDEPPGT--PVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL---ITVAQP 428 ++AE PG+ PV D D ++ Y I N S +N + + + QP Sbjct: 596 KIAELTEPGSRFPVEGAQDFDVDSNDIQAYSIIPENKFFTVSYEKKNEGDIQVQLVLQQP 655 Query: 429 LDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD +++ T+ ATD G RS T + I + D N+ AP+F + YT + E AP G+ Sbjct: 656 LDREEQSELDFTLVATDGGSPPRSGTTQIHIIVMDVNDNAPIFTHDIYTGHIAESAPEGS 715 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 VL V ATD+DVG N I+Y S +S A F IN G I LD ET Sbjct: 716 LVLRVMATDADVGTNGDISYQFSQVVSQSQSA-----FTINTTNGEIRVKTPLDFETTHK 770 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y L V A DGG LS V + V+DVNDN P +++ I E+ GT V+ + Sbjct: 771 YELGVRATDGG--GLSALCKVLVEVMDVNDNAPEIVVSSFSSPIPENVEPGTVVALLAVR 828 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASG---VIRTNKALDRESVATHDLKAVAIDGG 663 D D G+NG I L+ E+ SF + PA + T LDRE A H + A D G Sbjct: 829 DQDSGVNGEITCALE----EQLSFALRPAFKNYYELVTVSRLDREERAQHMVVVTAADAG 884 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 +PP +ST + I D+ND+ PVF T Y+ EN+ +G ++A D D GPNA V Sbjct: 885 SPPLTSTHTFSVDISDVNDNAPVFNQTSYTMYVHENNAPALLVGAVKATDADAGPNAKVS 944 Query: 724 YSI---KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWND 777 YS+ +G ++ + S+ + + LDYE R+ E+V+ AA SPPL + Sbjct: 945 YSVVPARGPEEEPCSCVSVN--SESGGVFVLRPLDYEQLRQ-LEVVVSAADAGSPPLSSS 1001 Query: 778 VRVEILVTDVNDNAPVM 794 V V +LV D NDNAP++ Sbjct: 1002 VSVRLLVVDENDNAPLV 1018 Score = 74.1 bits (174), Expect = 5e-11 Identities = 53/200 (26%), Positives = 91/200 (45%), Gaps = 22/200 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +++ D ND++PVF Y V E + V +KATD D G NA+V Y++ Sbjct: 896 VDISDVNDNAPVFNQTSYTMYVHENNAPALLVGAVKATDADAGPNAKVSYSV----VPAR 951 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 PE+ ++ SG + LD E++ + V+V A D SP L Sbjct: 952 GPEEEPCSCVS----------VNSESGGVFVLRPLDYEQLRQLEVVVSAADAGSPP---L 998 Query: 131 SSTATIHVNIIDDNDN-----YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 SS+ ++ + ++D+NDN +P + + S +++K+ A DAD G NS Sbjct: 999 SSSVSVRLLVVDENDNAPLVLHPSAQDSSPPSSELVPAGAEAGDLVSKVVAVDADSGQNS 1058 Query: 186 AIRYAIIGGNTQMQFSIDSL 205 + Y ++ F+I ++ Sbjct: 1059 WLSYQLLRATEPGLFAIGTV 1078 >UniRef50_UPI00015B6339 Cluster: PREDICTED: similar to ENSANGP00000011295; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to ENSANGP00000011295 - Nasonia vitripennis Length = 1949 Score = 294 bits (722), Expect = 2e-77 Identities = 262/883 (29%), Positives = 413/883 (46%), Gaps = 89/883 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++++ D ND P F+ ++Y A + EGA L ++A D+D K +++ Y+I V + Sbjct: 661 RLSLADANDSPPKFQHKKYRAVIDEGAEKFEPPLRVQARDRD--KTSKITYSI--VEGNK 716 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSG--ALLTRASLDREKVARYTVLVKATDQASPVS 127 + +FRID SG + RA +D + T QAS Sbjct: 717 MG-----------------IFRIDSDSGEITIAKRAPVDMSNSTNGGDSISLTVQAS--D 757 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 S A I + + D N+N P F+ YT S+ E V V+ ++ ATDAD G N+ + Sbjct: 758 GTFSDKALISITVRDVNNNAPAFAHDLYTASIPELSPV--GTVVEELTATDADSGINAEL 815 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 Y I G F+++ SG V + + LDY+Q +Y + + A D GSPS + TT L+IN+ Sbjct: 816 VYRIQKGGFN-DFAVNETSGAVFVSRKLDYDQRNTYHVEVIAFDKGSPSLTGTTTLMINV 874 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD----EGVNAELTYTMTDKDYTG 303 + ND P F + V+E+ IG ++A D D E +N ++ +T D G Sbjct: 875 ENSNDKPPYFSPGTQRAEVTEDTAIGTVFTTLKAIDPDSTDPEALNFAISEPITAIDRNG 934 Query: 304 -NVDLPIT-------IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP-RSATATXXX 354 V+ T +D ++G V LDR+ A L + TD P + Sbjct: 935 QRVNDSTTAFKDFFAVDRKTGQVSVVKSLDRDIAATVSLTLVVTDTSAPTLQQGKGNLVV 994 Query: 355 XXXXXXXXXXXFM------PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT 408 F +Y +E+ E++P G V TATDAD +N Y I + Sbjct: 995 TIIDVNHFAPEFARPWTREDPKYSIEMQEEQPTGAIVGAFTATDAD-NNIAGYAIEPPSP 1053 Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYA 466 F I N G++ +Q +D+++ ++ TV A D+G S +A V + I + N+ Sbjct: 1054 --YFHI--NNVTGIVRTSQIIDYEETKQLEFTVVAYDTGVPQLSTSAKVTVTIINVNDED 1109 Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 P FE+ Y A+V E++ GT V VV A D+D G ++TYSL + H F I Sbjct: 1110 PKFEHKSYNATVKENSQPGTRVTVVKAIDADEGPFGEVTYSL--------IGEHASDFNI 1161 Query: 527 NPQTGAITTN--KLLDRETMSGYLLTVTARDGGVPSLSDTTDVE--ISVVDVNDNEPVFK 582 +TG IT +LDRE + ++V A D + +T V I +VDVNDN P+F Sbjct: 1162 GHETGEITVGGATVLDREIIPEITISVMASDNAPMNSRRSTSVPVVIKLVDVNDNRPIFT 1221 Query: 583 QQLYTANIMEDALVG--TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640 Q Y A++ E+ V + QV A D D G+NG + Y++ K E GSF ++P +G++ Sbjct: 1222 QHSYRASVAENLSVNPPAPILQVRAVDNDEGVNGEVWYKI-IKGNENGSFALNPETGILY 1280 Query: 641 TNKALDRESVATHDLKAVAID-GGTPPQSSTVIVHIKIEDINDSPPVF---ESDCLTFYI 696 +L ++ +K A D G P T +++++ +N P F E T + Sbjct: 1281 PAVSL-LGRAQSYKIKVEARDMAGKGPHFDTCNIYVRVIPVNQHKPEFIMPELPNATVEV 1339 Query: 697 SEN-SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755 EN + ++A D D G N V Y +K G+ + + E + EL + LD Sbjct: 1340 PENGGEPNYLVMTVKAIDRDSGDNGKVSYHMKVGNRNVQETEEFSINQETGELRAKIILD 1399 Query: 756 YESPRKKYELVIRAA---SPPLWNDVR-VEILVTDVNDNAPVMKD---FQIIFNNYKDCF 808 E+ + K+ELV+ AA SP + +R + +L+ D NDN P + F + N KD + Sbjct: 1400 RET-KNKFELVLVAADHGSPTAYETLRLLTVLLIDTNDNVPEFYEEYNFNVPENRPKDYY 1458 Query: 809 PVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSM 849 G+V A D D K+ Y I +GN ++++ GS+ Sbjct: 1459 ----VGKVTAEDKDEGRHAKVYYYIKAGNADRAFYIDKSDGSI 1497 Score = 246 bits (603), Expect = 5e-63 Identities = 202/699 (28%), Positives = 324/699 (46%), Gaps = 65/699 (9%) Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +++ ++ +++ D ND+ P+F K Y +DE + P+ +++A D D S I Y+ Sbjct: 655 TTSVSLRLSLADANDSPPKFQHKKYRAVIDEGAEKFEPPL--RVQARDRD--KTSKITYS 710 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR------LVIRAQDGGSPSRSNTTQLL 244 I+ GN F IDS SG++++ K + S L ++A DG + S+ + Sbjct: 711 IVEGNKMGIFRIDSDSGEITIAKRAPVDMSNSTNGGDSISLTVQASDG---TFSDKALIS 767 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 I +RDVN+NAP F L+ S+ E P+G + + A DAD G+NAEL Y + + Sbjct: 768 ITVRDVNNNAPAFAHDLYTASIPELSPVGTVVEELTATDADSGINAELVYRIQKGGFND- 826 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 ++ SG V+ S +LD + + Y + V A D G P + T T Sbjct: 827 ----FAVNETSGAVFVSRKLDYDQRNTYHVEVIAFDKGSPSLTGTTTLMINVENSNDKPP 882 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNT-------RGRFSIT 415 F PG E+ ED GT TL A D D + L++ I+ T R S T Sbjct: 883 YFSPGTQRAEVTEDTAIGTVFTTLKAIDPDSTDPEALNFAISEPITAIDRNGQRVNDSTT 942 Query: 416 S-------QNGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNY 465 + G ++V + LD LT+ TD+ + + + I D N++ Sbjct: 943 AFKDFFAVDRKTGQVSVVKSLDRDIAATVSLTLVVTDTSAPTLQQGKGNLVVTIIDVNHF 1002 Query: 466 APVF------ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAH 519 AP F E+ Y+ + E+ P G V +ATD+D + I+ A+ Sbjct: 1003 APEFARPWTREDPKYSIEMQEEQPTGAIVGAFTATDAD------------NNIAGYAIEP 1050 Query: 520 HDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP 579 F IN TG + T++++D E TV A D GVP LS + V +++++VND +P Sbjct: 1051 PSPYFHINNVTGIVRTSQIIDYEETKQLEFTVVAYDTGVPQLSTSAKVTVTIINVNDEDP 1110 Query: 580 VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639 F+ + Y A + E++ GT V+ V A DAD G G + Y L + + F I +G I Sbjct: 1111 KFEHKSYNATVKENSQPGTRVTVVKAIDADEGPFGEVTYSLIGEHASD--FNIGHETGEI 1168 Query: 640 RTNKA--LDRESVATHDLKAVAIDGG--TPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695 A LDRE + + +A D +S++V V IK+ D+ND+ P+F Sbjct: 1169 TVGGATVLDREIIPEITISVMASDNAPMNSRRSTSVPVVIKLVDVNDNRPIFTQHSYRAS 1228 Query: 696 ISENSPIG--TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753 ++EN + I ++RA D DEG N V Y I G+++ SF+L G V+++ Sbjct: 1229 VAENLSVNPPAPILQVRAVDNDEGVNGEVWYKIIKGNENGSFALNPETGI-LYPAVSLLG 1287 Query: 754 LDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP 792 +S + K E A P ++ + + V VN + P Sbjct: 1288 -RAQSYKIKVEARDMAGKGPHFDTCNIYVRVIPVNQHKP 1325 Score = 236 bits (578), Expect = 6e-60 Identities = 222/820 (27%), Positives = 364/820 (44%), Gaps = 72/820 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI-ELVTADT 69 INV + ND P F A V E + GT TLKA D D + + I E +TA Sbjct: 872 INVENSNDKPPYFSPGTQRAEVTEDTAIGTVFTTLKAIDPDSTDPEALNFAISEPITAID 931 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N + +D F +D ++G + SLDR+ A ++ + TD ++P + Sbjct: 932 RNGQRVNDSTTAF----KDFFAVDRKTGQVSVVKSLDRDIAATVSLTLVVTDTSAPTLQQ 987 Query: 130 LSSTATIHVNIIDDNDNYPQFS------EKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183 + V IID N P+F+ + Y++ + E+ ++ ATDAD Sbjct: 988 --GKGNLVVTIIDVNHFAPEFARPWTREDPKYSIEMQEEQPT--GAIVGAFTATDAD--- 1040 Query: 184 NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 N+ YAI + F I++++G V + +DYE+ + + A D G P S + ++ Sbjct: 1041 NNIAGYAIEPPSPY--FHINNVTGIVRTSQIIDYEETKQLEFTVVAYDTGVPQLSTSAKV 1098 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 + I +VND P+F + +V EN G + V+A DADEG E+TY++ G Sbjct: 1099 TVTIINVNDEDPKFEHKSYNATVKENSQPGTRVTVVKAIDADEGPFGEVTYSL-----IG 1153 Query: 304 NVDLPITIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGG--DPPRSATATXXXXXXXX 359 I +G + G LDRE + + V A+D + RS + Sbjct: 1154 EHASDFNIGHETGEITVGGATVLDREIIPEITISVMASDNAPMNSRRSTSVPVVIKLVDV 1213 Query: 360 XXXXXXFMPGQYEVELAED--EPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSIT 415 F Y +AE+ P P++ + A D DE + + Y+I GN G F++ Sbjct: 1214 NDNRPIFTQHSYRASVAENLSVNPPAPILQVRAVDNDEGVNGEVWYKIIKGNENGSFALN 1273 Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS---DTAMVQINITDANNYAPVF--- 469 + G++ A L + + Y + V A D G+ DT + + + N + P F Sbjct: 1274 PET--GILYPAVSL-LGRAQSYKIKVEARDMAGKGPHFDTCNIYVRVIPVNQHKPEFIMP 1330 Query: 470 ENAPYTASVFED-APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528 E T V E+ V+ V A D D G N +++Y + ++ N V ++F IN Sbjct: 1331 ELPNATVEVPENGGEPNYLVMTVKAIDRDSGDNGKVSYHM--KVGNRNV-QETEEFSINQ 1387 Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD-VEISVVDVNDNEPVFKQQLYT 587 +TG + +LDRET + + L + A D G P+ +T + + ++D NDN P F ++ Y Sbjct: 1388 ETGELRAKIILDRETKNKFELVLVAADHGSPTAYETLRLLTVLLIDTNDNVPEFYEE-YN 1446 Query: 588 ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647 N+ E+ V +V A D D G + +++Y + + + +F ID + G I TN++ DR Sbjct: 1447 FNVPENRPKDYYVGKVTAEDKDEGRHAKVYYYIKAGNADR-AFYIDKSDGSIYTNRSFDR 1505 Query: 648 ESVATHDLKAVA-------IDGGTPPQSSTVIVH------IKIEDINDSPPVFESDCLTF 694 E ++ L +A +D S + H IKI D ND+PP FE Sbjct: 1506 EKRDSYLLTILAANDPDIYVDPKDTDHSRKNLEHGYVNVTIKILDENDNPPAFERSAYFA 1565 Query: 695 YISENSPIGTTIGEIRAHDPDEGPNAVVHYSI------KGGDDSNSFSL--ETRQGSDKA 746 ++ + I + ++ A D D G N + Y + K G D S S+ + Sbjct: 1566 GVNSMANINELVTKVTASDADLGDNGTLQYYVASANLYKYGSDKPSGSIVPSPFNVTQDG 1625 Query: 747 ELVTMVDL-DYESPRKKYELVIR-AASPPLWNDVRVEILV 784 +LVT + +Y R E+V + ASP + +V + V Sbjct: 1626 KLVTSGYMAEYNQDRFIVEIVAKEIASPERFAVTKVHVWV 1665 Score = 194 bits (472), Expect = 4e-47 Identities = 176/677 (25%), Positives = 292/677 (43%), Gaps = 51/677 (7%) Query: 201 SIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260 ++ + GD + + + YE V S A D ++ + L +++ D ND+ P+F Sbjct: 622 TVKARDGDRGMPRKIVYELVTSES----ATDDNGKGQTTSVSLRLSLADANDSPPKFQHK 677 Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT 320 ++ + E +RVQA D D+ +++TY++ + GN ID SG + Sbjct: 678 KYRAVIDEGAEKFEPPLRVQARDRDK--TSKITYSIVE----GNKMGIFRIDSDSGEITI 731 Query: 321 SGQ----LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376 + + + T + +T D S A F Y + Sbjct: 732 AKRAPVDMSNSTNGGDSISLTV-QASDGTFSDKALISITVRDVNNNAPAFAHDLYTASIP 790 Query: 377 EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR-GLITVAQPLDFKQER 435 E P GT V LTATDAD ++ E+ +G F+ + N G + V++ LD+ Q Sbjct: 791 ELSPVGTVVEELTATDADSG--INAELVYRIQKGGFNDFAVNETSGAVFVSRKLDYDQRN 848 Query: 436 RYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 Y + V A D G S T + IN+ ++N+ P F A V ED IGT + A Sbjct: 849 TYHVEVIAFDKGSPSLTGTTTLMINVENSNDKPPYFSPGTQRAEVTEDTAIGTVFTTLKA 908 Query: 494 TDSDVGINAQITYSLSSEIS---------NEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 D D + +++S I+ N++ F ++ +TG ++ K LDR+ Sbjct: 909 IDPDSTDPEALNFAISEPITAIDRNGQRVNDSTTAFKDFFAVDRKTGQVSVVKSLDRDIA 968 Query: 545 SGYLLTVTARDGGVPSLSD-TTDVEISVVDVNDNEPVF------KQQLYTANIMEDALVG 597 + LT+ D P+L ++ ++++DVN P F + Y+ + E+ G Sbjct: 969 ATVSLTLVVTDTSAPTLQQGKGNLVVTIIDVNHFAPEFARPWTREDPKYSIEMQEEQPTG 1028 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 V ATDAD + G Y ++P F I+ +G++RT++ +D E + Sbjct: 1029 AIVGAFTATDADNNIAG---YAIEP---PSPYFHINNVTGIVRTSQIIDYEETKQLEFTV 1082 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 VA D G P S++ V + I ++ND P FE + ENS GT + ++A D DEG Sbjct: 1083 VAYDTGVPQLSTSAKVTVTIINVNDEDPKFEHKSYNATVKENSQPGTRVTVVKAIDADEG 1142 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP---PL 774 P V YS+ G+ ++ F++ G T++D + P ++ +P Sbjct: 1143 PFGEVTYSLI-GEHASDFNIGHETGEITVGGATVLDREI-IPEITISVMASDNAPMNSRR 1200 Query: 775 WNDVRVEILVTDVNDNAPV--MKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYR 830 V V I + DVNDN P+ ++ P P +V A D D V ++ Y+ Sbjct: 1201 STSVPVVIKLVDVNDNRPIFTQHSYRASVAENLSVNPPAPILQVRAVDNDEGVNGEVWYK 1260 Query: 831 ILSGNNANLILLNETTG 847 I+ GN LN TG Sbjct: 1261 IIKGNENGSFALNPETG 1277 Score = 151 bits (367), Expect = 2e-34 Identities = 161/642 (25%), Positives = 278/642 (43%), Gaps = 71/642 (11%) Query: 169 PVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIR 228 PV K+ S ++Y + +F +D +G ++L K LD E+ + R + Sbjct: 401 PVGTKVFTLKGHDPEGSPVKYGV---QLTDKFVVDQRTGVMTLAKPLDREEADTIRFRVT 457 Query: 229 AQDG---GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV-RVQAYDA 284 +D G + + + D NDN P+F ++ V+E+ P G +I+ ++ D Sbjct: 458 LEDSVPQGQQPNIVGVEAHVIVLDENDNPPQFLGVPYEAVVAEDSPPGTTILPAIRVTDP 517 Query: 285 DE-GVNAELTYTMTDK-----DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA 338 D G N ++T + G V++ + D G + LD + + YQLL+ A Sbjct: 518 DLLGENIQVTCIPQPQFPDACTKFGIVNIERSQDTYIGALVLQQPLDYKERPFYQLLLQA 577 Query: 339 TDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--D 396 +DG + + + G + ED+P GT V+T+ A D D Sbjct: 578 SDGSNSNSTGVEIKVTDIQNSPPEFLDSLTG----VVKEDDPIGTLVMTVKARDGDRGMP 633 Query: 397 NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ 456 ++ YE+ S T NG+G T L +S D Sbjct: 634 RKIVYELVTSE-----SATDDNGKGQTTSVS-----------LRLSLAD----------- 666 Query: 457 INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL--SSEISN 514 AN+ P F++ Y A + E A L V A D D ++ITYS+ +++ Sbjct: 667 -----ANDSPPKFQHKKYRAVIDEGAEKFEPPLRVQARDRDK--TSKITYSIVEGNKMGI 719 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 + + I + +N +++S LTV A DG + SD + I+V DV Sbjct: 720 FRIDSDSGEITIAKRAPVDMSNSTNGGDSIS---LTVQASDG---TFSDKALISITVRDV 773 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634 N+N P F LYTA+I E + VGT V ++ ATDAD G+N + Y + + F ++ Sbjct: 774 NNNAPAFAHDLYTASIPELSPVGTVVEELTATDADSGINAELVYRIQKGGFND--FAVNE 831 Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694 SG + ++ LD + T+ ++ +A D G+P + T + I +E+ ND PP F Sbjct: 832 TSGAVFVSRKLDYDQRNTYHVEVIAFDKGSPSLTGTTTLMINVENSNDKPPYFSPGTQRA 891 Query: 695 YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDL 754 ++E++ IGT ++A DPD ++++I S + R G + T Sbjct: 892 EVTEDTAIGTVFTTLKAIDPDSTDPEALNFAI-----SEPITAIDRNGQRVNDSTTAFKD 946 Query: 755 DYESPRKKYEL-VIRAASPPLWNDVRVEILVTDVNDNAPVMK 795 + RK ++ V+++ + V + ++VTD +AP ++ Sbjct: 947 FFAVDRKTGQVSVVKSLDRDIAATVSLTLVVTDT--SAPTLQ 986 Score = 94.3 bits (224), Expect = 4e-17 Identities = 133/503 (26%), Positives = 212/503 (42%), Gaps = 42/503 (8%) Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434 L E P GT V TL D E + + Y G +F + + G ++T+A+PLD ++ Sbjct: 396 LNEATPVGTKVFTLKGHDP-EGSPVKY---GVQLTDKFVVDQRTG--VMTLAKPLDREEA 449 Query: 435 RRYVLTVSATDS---GGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVL 489 V+ DS G + + V+ ++ D N+ P F PY A V ED+P GTT+L Sbjct: 450 DTIRFRVTLEDSVPQGQQPNIVGVEAHVIVLDENDNPPQFLGVPYEAVVAEDSPPGTTIL 509 Query: 490 -VVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFVINPQT--GAITTNKLLDRETMS 545 + TD D +G N Q+T + + + T GA+ + LD + Sbjct: 510 PAIRVTDPDLLGENIQVTCIPQPQFPDACTKFGIVNIERSQDTYIGALVLQQPLDYKERP 569 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 Y L + A DG S S++T VEI V D+ ++ P F L T + ED +GT V V A Sbjct: 570 FYQLLLQASDG---SNSNSTGVEIKVTDIQNSPPEFLDSL-TGVVKEDDPIGTLVMTVKA 625 Query: 606 TDADVGLNGRIHYEL---DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 D D G+ +I YEL + + G S + A D H ID Sbjct: 626 RDGDRGMPRKIVYELVTSESATDDNGKGQTTSVSLRLSLADANDSPPKFQHKKYRAVIDE 685 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 G + V + D ++ +T+ I E + +G + + + A V Sbjct: 686 GAEKFEPPLRVQARDRD--------KTSKITYSIVEGNKMGIFRIDSDSGEITIAKRAPV 737 Query: 723 HYS-IKGGDDSNSFSLETRQG--SDKAEL-VTMVDLDYESPRKKYELVIRAASPPL--WN 776 S G DS S +++ G SDKA + +T+ D++ +P ++L A+ P L Sbjct: 738 DMSNSTNGGDSISLTVQASDGTFSDKALISITVRDVNNNAPAFAHDL-YTASIPELSPVG 796 Query: 777 DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNN 836 V E+ TD + ++I + D F V V+ KL Y + + Sbjct: 797 TVVEELTATDADSGINAELVYRIQKGGFND-FAVNETSGA----VFVSRKLDYDQRNTYH 851 Query: 837 ANLILLNETTGSMTLSPQLNTNV 859 +I ++ + S+T + L NV Sbjct: 852 VEVIAFDKGSPSLTGTTTLMINV 874 Score = 86.6 bits (205), Expect = 9e-15 Identities = 68/242 (28%), Positives = 107/242 (44%), Gaps = 15/242 (6%) Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 TL D + D F +D R+G + LDRE+ V D Sbjct: 408 TLKGHDPEGSPVKYGVQLTDKFVVDQRTGVMTLAKPLDREEADTIRFRVTLEDSVPQGQQ 467 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSAI 187 HV ++D+NDN PQF Y V ED S ++ I+ TD D +G N + Sbjct: 468 PNIVGVEAHVIVLDENDNPPQFLGVPYEAVVAED-SPPGTTILPAIRVTDPDLLGENIQV 526 Query: 188 R---------YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238 G ++ S D+ G + L + LDY++ Y+L+++A DG S S Sbjct: 527 TCIPQPQFPDACTKFGIVNIERSQDTYIGALVLQQPLDYKERPFYQLLLQASDG---SNS 583 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 N+T + I + D+ ++ P F SL V E+ PIG ++ V+A D D G+ ++ Y + Sbjct: 584 NSTGVEIKVTDIQNSPPEFLDSL-TGVVKEDDPIGTLVMTVKARDGDRGMPRKIVYELVT 642 Query: 299 KD 300 + Sbjct: 643 SE 644 Score = 83.0 bits (196), Expect = 1e-13 Identities = 74/258 (28%), Positives = 115/258 (44%), Gaps = 26/258 (10%) Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 +++E P+G + ++ +D EG + +TDK +D R+G + + L Sbjct: 395 TLNEATPVGTKVFTLKGHDP-EGSPVKYGVQLTDK---------FVVDQRTGVMTLAKPL 444 Query: 325 DRETQAKYQLLVTATDG---GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381 DRE + VT D G P F+ YE +AED PP Sbjct: 445 DREEADTIRFRVTLEDSVPQGQQPNIVGVEAHVIVLDENDNPPQFLGVPYEAVVAEDSPP 504 Query: 382 GTPVV-TLTATDAD---EDNRL----HYEITGGNTR-GRFSITSQNGR--GLITVAQPLD 430 GT ++ + TD D E+ ++ + T+ G +I G + + QPLD Sbjct: 505 GTTILPAIRVTDPDLLGENIQVTCIPQPQFPDACTKFGIVNIERSQDTYIGALVLQQPLD 564 Query: 431 FKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 +K+ Y L + A+D G S++ V+I +TD N P F ++ T V ED PIGT V+ Sbjct: 565 YKERPFYQLLLQASD-GSNSNSTGVEIKVTDIQNSPPEFLDS-LTGVVKEDDPIGTLVMT 622 Query: 491 VSATDSDVGINAQITYSL 508 V A D D G+ +I Y L Sbjct: 623 VKARDGDRGMPRKIVYEL 640 Score = 72.1 bits (169), Expect = 2e-10 Identities = 87/298 (29%), Positives = 128/298 (42%), Gaps = 26/298 (8%) Query: 556 GGVPSLSDTTDVEISVVDVNDNEP-VFKQQLYTAN--IMEDALVGTSVSQVGATDADVGL 612 G P L+ + V N NEP +F Y + E VGT V + D + Sbjct: 359 GRSPLLAALLLLATCVAGNNVNEPPIFDGSGYPMGWTLNEATPVGTKVFTLKGHDPE--- 415 Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG---GTPPQSS 669 + Y + D+ FV+D +GV+ K LDRE T + D G P Sbjct: 416 GSPVKYGVQLTDK----FVVDQRTGVMTLAKPLDREEADTIRFRVTLEDSVPQGQQPNIV 471 Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI-GEIRAHDPD-EGPNAVVHY--S 725 V H+ + D ND+PP F ++E+SP GTTI IR DPD G N V Sbjct: 472 GVEAHVIVLDENDNPPQFLGVPYEAVVAEDSPPGTTILPAIRVTDPDLLGENIQVTCIPQ 531 Query: 726 IKGGDDSNSF---SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEI 782 + D F ++E Q + LV LDY+ R Y+L+++A+ N VEI Sbjct: 532 PQFPDACTKFGIVNIERSQDTYIGALVLQQPLDYKE-RPFYQLLLQASDGSNSNSTGVEI 590 Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDAD--VTDKLQYRILSGNNA 837 VTD+ ++ P D + K+ P+G V A D D + K+ Y +++ +A Sbjct: 591 KVTDIQNSPPEFLD--SLTGVVKEDDPIGTLVMTVKARDGDRGMPRKIVYELVTSESA 646 Score = 52.0 bits (119), Expect = 2e-04 Identities = 50/188 (26%), Positives = 87/188 (46%), Gaps = 21/188 (11%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVL-TLKATDQD-IGKNAEVEYTIEL 64 + + VLD ND+ P F YEA V E + GTT+L ++ TD D +G+N +V Sbjct: 473 VEAHVIVLDENDNPPQFLGVPYEAVVAEDSPPGTTILPAIRVTDPDLLGENIQV------ 526 Query: 65 VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS 124 T P+ V D GAL+ + LD ++ Y +L++A+D ++ Sbjct: 527 ----TCIPQPQFPDACTKFGIVNIERSQDTYIGALVLQQPLDYKERPFYQLLLQASDGSN 582 Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184 S++ + + + D ++ P+F + + T V ED + ++ +KA D D G Sbjct: 583 ------SNSTGVEIKVTDIQNSPPEFLD-SLTGVVKEDDPI--GTLVMTVKARDGDRGMP 633 Query: 185 SAIRYAII 192 I Y ++ Sbjct: 634 RKIVYELV 641 Score = 44.8 bits (101), Expect = 0.035 Identities = 39/147 (26%), Positives = 68/147 (46%), Gaps = 16/147 (10%) Query: 753 DLDYESPRK-KYELVIRAASPP-----LWNDVRVEILVTDVNDNAPVM--KDFQIIFNNY 804 D D PRK YELV ++ V + + + D ND+ P K ++ + + Sbjct: 627 DGDRGMPRKIVYELVTSESATDDNGKGQTTSVSLRLSLADANDSPPKFQHKKYRAVIDEG 686 Query: 805 KDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQL------NTN 858 + F P RV A D D T K+ Y I+ GN + ++ +G +T++ + +TN Sbjct: 687 AEKFE--PPLRVQARDRDKTSKITYSIVEGNKMGIFRIDSDSGEITIAKRAPVDMSNSTN 744 Query: 859 VPKLATMEVSVTDGVNEIKAMMQLSVR 885 ++ V +DG KA++ ++VR Sbjct: 745 GGDSISLTVQASDGTFSDKALISITVR 771 Score = 41.5 bits (93), Expect = 0.32 Identities = 19/56 (33%), Positives = 30/56 (53%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 ++ I +LD ND+ P FE Y A V A+ V + A+D D+G N ++Y + Sbjct: 1542 VNVTIKILDENDNPPAFERSAYFAGVNSMANINELVTKVTASDADLGDNGTLQYYV 1597 >UniRef50_Q08174 Cluster: Protocadherin-1 precursor; n=52; Euteleostomi|Rep: Protocadherin-1 precursor - Homo sapiens (Human) Length = 1026 Score = 294 bits (721), Expect = 3e-77 Identities = 209/735 (28%), Positives = 347/735 (47%), Gaps = 53/735 (7%) Query: 91 RIDGRSGALLT-RASLDREKVARYT--------VL---VKATDQASPVSDRLSSTATIHV 138 R+DG++G + T S+DRE + +L V TD S RL + Sbjct: 78 RVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNASPRLLEG---QI 134 Query: 139 NIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQM 198 + D NDN P F+ T+++ E+ ++ + A+D D G N Y + Q+ Sbjct: 135 EVQDINDNTPNFASPVITLAIPENTNI--GSLFPIPLASDRDAGPNGVASYEL-----QV 187 Query: 199 QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY 258 + + ++ LD E+ SY L I+ QDGGSP R+ + L + + D NDNAP+F Sbjct: 188 AEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRATSALLRVTVLDTNDNAPKFE 247 Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV 318 ++ +SEN PIG+S+++V+A D+D+G NAE+ YT V + +D +G + Sbjct: 248 RPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEV--VRRLLRLDRNTGLI 305 Query: 319 YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF-MPG-------Q 370 G +DRE + + V A D G P+SA A + G Sbjct: 306 TVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQD 365 Query: 371 YEVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQNG-----RGLIT 424 ++ED T V + +D DE +N + G+ + S+ G + + Sbjct: 366 GMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQ 425 Query: 425 VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 PLD+++ + Y + + A DSG S T +++ + D N+ APVF + + E+ Sbjct: 426 TTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENN 485 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 G + ++A+D+D G NA++ YSL E + + + F I+P+TG I LDRE Sbjct: 486 KPGEVIAEITASDADSGSNAELVYSLEPEPAAKGL------FTISPETGEIQVKTSLDRE 539 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 Y L V A D G PSL T V ++V+D NDN+P F Y ++ME+ + V Sbjct: 540 QRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGM 599 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 V D D G N ++ + +++ G FVI +G I ++ + DRE +T+ + A+DG Sbjct: 600 VTVIDGDKGENAQVQLSV---EQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDG 656 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY--ISENSPIGTTIGEIRAHDPDEGPNA 720 G PP+S+ V V I + D ND+ P + T + ++ + +G T+ ++ A D D G NA Sbjct: 657 GVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNA 716 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRV 780 + YSI GG+ F + + G+ L ++ + + V PP + V Sbjct: 717 ELIYSIAGGNPYGLFQIGSHSGA--ITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALV 774 Query: 781 EILVTDVNDNAPVMK 795 + V + N +++ Sbjct: 775 HLYVNETLANRTLLE 789 Score = 247 bits (605), Expect = 3e-63 Identities = 197/695 (28%), Positives = 314/695 (45%), Gaps = 60/695 (8%) Query: 4 PFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIE 63 P + QI V D ND++P F ++ E + G+ A+D+D G N Y ++ Sbjct: 127 PRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQ 186 Query: 64 LVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQA 123 + ED + + L+ +LDRE+ Y + +K D Sbjct: 187 VA-------EDQ-----------------EEKQPQLIVMGNLDRERWDSYDLTIKVQDGG 222 Query: 124 SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183 SP +++A + V ++D NDN P+F +Y + E+ + + + ++KA D+D GA Sbjct: 223 SPPR---ATSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHS--VIQVKANDSDQGA 277 Query: 184 NSAIRYAIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 N+ I Y ++ +D +G +++ +D E + + R + A+D G+ +S Sbjct: 278 NAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARA 337 Query: 242 QLLINIRDVNDNAPRFYTS-----LFQE---SVSENVPIGYSIVRVQAYDADEGVNAELT 293 Q+++ ++D+NDNAP Q+ ++SE+V ++ VQ D DEG NA +T Sbjct: 338 QVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVT 397 Query: 294 YTMT-DKDYTGNVDLPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 + D + D + + + T+ LD E Y + + A D G+PP S+T + Sbjct: 398 CVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNS 457 Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNT- 408 F EV E+ PG + +TA+DAD + L Y + Sbjct: 458 LKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAA 517 Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYA 466 +G F+I+ + G I V LD +Q Y L V A D G S TA V +N+ D N+ Sbjct: 518 KGLFTISPETGE--IQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDND 575 Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 P F + Y SV E+ P + V +V+ D D G NAQ+ S+ + + FVI Sbjct: 576 PKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQD---------NGDFVI 626 Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586 TG I ++ DRE S Y + A DGGVP S V I+V+D NDN P Sbjct: 627 QNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSN 686 Query: 587 TAN--IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA 644 T++ + +G +VSQV A D D G+N + Y + G F I SG I K Sbjct: 687 TSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSI-AGGNPYGLFQIGSHSGAITLEKE 745 Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679 ++R H L D G PP+ T +VH+ + + Sbjct: 746 IERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNE 780 Score = 247 bits (604), Expect = 4e-63 Identities = 183/645 (28%), Positives = 286/645 (44%), Gaps = 34/645 (5%) Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 I ++D+NDN P F + + ++ EN IG A D D G N +Y + + Sbjct: 134 IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQVAEDQ-- 191 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 + + + G LDRE Y L + DGG PPR+ +A Sbjct: 192 -------EEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRATSALLRVTVLDTNDNAP 244 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG--RFSITSQNGRGL 422 F YE EL+E+ P G V+ + A D+D+ E T R + GL Sbjct: 245 KFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGL 304 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFE--------NA 472 ITV P+D + +V A D G +A Q+ +T D N+ AP E + Sbjct: 305 ITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQ 364 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 A++ ED T V +V +D D G NA +T ++ ++ + + + + + Sbjct: 365 DGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQ-LRQASETGSDSKKKYF 423 Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592 + T LD E + Y + + A D G P LS T +++ VVDVNDN PVF Q + E Sbjct: 424 LQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPE 483 Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652 + G ++++ A+DAD G N + Y L+P+ +G F I P +G I+ +LDRE + Sbjct: 484 NNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRES 543 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 ++LK VA D G+P T V + + D ND+ P F F + EN P + +G + Sbjct: 544 YELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVI 603 Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP 772 D D+G NA V S++ D+ F ++ G+ + L D + +S + P Sbjct: 604 DGDKGENAQVQLSVE--QDNGDFVIQNGTGTILSSL--SFDREQQSTYTFQLKAVDGGVP 659 Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA------YDADVTDK 826 P V V I V D NDNAP + ++K P G + +D+ V + Sbjct: 660 PRSAYVGVTINVLDENDNAPYIT--APSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAE 717 Query: 827 LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 L Y I GN L + +G++TL ++ L + V V+D Sbjct: 718 LIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSD 762 Score = 234 bits (573), Expect = 2e-59 Identities = 195/648 (30%), Positives = 295/648 (45%), Gaps = 70/648 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ VLD ND++P FE YEA + E + G +V+ +KA D D G NAE+EYT Sbjct: 233 RVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQA---- 288 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 PE V+ + R+D +G + + +DRE ++ V A D+ + + Sbjct: 289 --PE-----------VVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGT---NP 332 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED----IS--VTDNPVIAKIKATDADVGA 183 S+ A + V + D NDN P + + +D IS V + +A ++ +D D G Sbjct: 333 KSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGE 392 Query: 184 NSAIRYAIIGGNTQMQFSIDSLSGDVSLVK-------TLDYEQVRSYRLVIRAQDGGSPS 236 N+A+ ++ G+ Q S +G S K LDYE+V+ Y + I A D G+P Sbjct: 393 NAAVT-CVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPP 451 Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 S+T L + + DVNDNAP F S+ + + EN G I + A DAD G NAEL Y++ Sbjct: 452 LSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSL 511 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 + + TI P +G + LDRE + Y+L V A D G P TAT Sbjct: 512 EPEPAAKGL---FTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNV 568 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITS 416 FM Y + E+ P +PV +T D D+ +++ G F I Sbjct: 569 LDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVI-- 626 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPY 474 QNG G I + D +Q+ Y + A D G RS V IN+ D N+ AP + AP Sbjct: 627 QNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAP-YITAPS 685 Query: 475 TAS---VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 S + +G TV V+A D D G+NA++ YS+ A + F I +G Sbjct: 686 NTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSI-------AGGNPYGLFQIGSHSG 738 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 AIT K ++R + L V D G P T V + V NE + + L Sbjct: 739 AITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYV-----NETLANRTLL----- 788 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639 + L+G S+ T D+ + G YE + ++ G+ + +GV+ Sbjct: 789 -ETLLGHSLD----TPLDIDIAGDPEYE---RSKQRGNILFGVVAGVV 828 Score = 182 bits (444), Expect = 1e-43 Identities = 153/507 (30%), Positives = 239/507 (47%), Gaps = 40/507 (7%) Query: 429 LDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD ++ Y LT+ D G R+ +A++++ + D N+ AP FE Y A + E++PIG Sbjct: 204 LDRERWDSYDLTIKVQDGGSPPRATSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGH 263 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 +V+ V A DSD G NA+I Y+ + E V + ++ TG IT +DRE +S Sbjct: 264 SVIQVKANDSDQGANAEIEYTFHQ--APEVVR---RLLRLDRNTGLITVQGPVDREDLST 318 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ---LYT-----ANIMEDALVGT 598 +V A+D G S V ++V D+NDN P + + L T ANI ED T Sbjct: 319 LRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEET 378 Query: 599 SVSQVGATDADVGLN--------GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650 +V+ V +D D G N G + ++L E GS ++T LD E V Sbjct: 379 AVALVQVSDRDEGENAAVTCVVAGDVPFQLRQAS-ETGSD--SKKKYFLQTTTPLDYEKV 435 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710 + ++ VA+D G PP SST + +++ D+ND+ PVF EN+ G I EI Sbjct: 436 KDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEIT 495 Query: 711 AHDPDEGPNAVVHYSIKGGDDSNS-FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 A D D G NA + YS++ + F++ G E+ LD E R+ YEL + A Sbjct: 496 ASDADSGSNAELVYSLEPEPAAKGLFTISPETG----EIQVKTSLDREQ-RESYELKVVA 550 Query: 770 A---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK 826 A SP L V + V D NDN P F+ ++ + P G V D D + Sbjct: 551 ADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGEN 610 Query: 827 LQYRI-LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSV 884 Q ++ + +N + ++ N TG++ S + T ++ D GV A + +++ Sbjct: 611 AQVQLSVEQDNGDFVIQN-GTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTI 669 Query: 885 RLITEEMLLNSITVRLNDMTAEQFLSP 911 ++ E IT N T+ + L+P Sbjct: 670 NVLDENDNAPYITAPSN--TSHKLLTP 694 Score = 148 bits (359), Expect = 2e-33 Identities = 123/417 (29%), Positives = 191/417 (45%), Gaps = 41/417 (9%) Query: 456 QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515 QI + D N+ P F + T ++ E+ IG+ + A+D D G N +Y L +++ + Sbjct: 133 QIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYEL--QVAED 190 Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575 Q V+ LDRE Y LT+ +DGG P + + + ++V+D N Sbjct: 191 QEEKQPQLIVMGN----------LDRERWDSYDLTIKVQDGGSPPRATSALLRVTVLDTN 240 Query: 576 DNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV-IDP 634 DN P F++ Y A + E++ +G SV QV A D+D G N I Y + +D Sbjct: 241 DNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDR 300 Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694 +G+I +DRE ++T +A D GT P+S+ V + ++D+ND+ P E + Sbjct: 301 NTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGL 360 Query: 695 Y--------ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD-- 744 ISE+ T + ++ D DEG NA V + GD + GSD Sbjct: 361 VTHQDGMANISEDVAEETAVALVQVSDRDEGENAAV-TCVVAGDVPFQLRQASETGSDSK 419 Query: 745 -KAELVTMVDLDYESPRK-KYELV-IRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801 K L T LDYE + E+V + + +PPL + +++ V DVNDNAPV Sbjct: 420 KKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEV 479 Query: 802 NNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNE----TTGSMTLSPQ 854 ++ P + A DAD SG+NA L+ E G T+SP+ Sbjct: 480 AFPENNKPGEVIAEITASDAD----------SGSNAELVYSLEPEPAAKGLFTISPE 526 >UniRef50_A7S9Y3 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 868 Score = 293 bits (720), Expect = 3e-77 Identities = 191/509 (37%), Positives = 271/509 (53%), Gaps = 27/509 (5%) Query: 140 IIDDNDNYPQF-SEKTYTVSVDEDISVTDNPV-IAKIKATDADVGANSAIRYAIIGGNTQ 197 I D N++ PQF S +YT + ED T V IA + ATDAD G++ AI +AII GN + Sbjct: 377 ISDVNEHTPQFTSGGSYTAVIAEDAPDTAIGVTIATVAATDADHGSDGAISFAIIAGNEE 436 Query: 198 MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF 257 +F ID+ SG + L + LD E SY L + A+D GSP++S+ + + + DVNDNAP Sbjct: 437 DKFLIDTTSGVIELKRPLDRESTGSYILTVLARDHGSPNKSSNASVDVTVVDVNDNAPNC 496 Query: 258 YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317 + V+EN +G +++ ++ D DEG N++LTY +T TG VD TID SG Sbjct: 497 SVTAHVVEVAENASVGSTVLELRCEDVDEGANSQLTYNIT----TG-VD--FTIDKSSGV 549 Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPP---RSATATXXXXXXXXXXXXXXFMPGQYEVE 374 V LDRET+ Y+L +T D G+ R+A F Y Sbjct: 550 VAVGSSLDRETRDLYELNITVRDRGNTEQERRAAVMQLTIEVTDENDNPPVFTQEIYTTT 609 Query: 375 LAEDEPPGTPVVTLTATDADED-NRLH-YEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432 + E+ G V + TD D N H Y ITGG+ G+FSI G+IT LD++ Sbjct: 610 IPENMASGASVARVATTDRDIGINANHTYSITGGDGLGKFSIVQST--GVITALPGLDYE 667 Query: 433 QERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 + Y L+++A D G A V+I ++D N+ PVF Y S+ E GT V+ Sbjct: 668 TKYTYYLSITARDRGSPQLYAVAGVRIFLSDTNDNKPVFSPTLYLTSISEATSAGTDVIP 727 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550 V ATD D GINA+ITYS+ + +A QF +N TG I T LDRE ++ Y L Sbjct: 728 VHATDVDTGINAEITYSI---VGGDA----KNQFSVN-STGMIRTIATLDREDIASYTLL 779 Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610 V A D GVP ++T V ++++DVNDN VF Q ++A ++EDA VG + A+DAD Sbjct: 780 VQASDRGVPPQTETVHVTVTILDVNDNAAVFSQSAFSARVLEDAPVGFRFMNISASDADS 839 Query: 611 GLNGRIHYELDPKDREEGSFVIDPASGVI 639 G N R+ Y + + I+ A+G + Sbjct: 840 GDNARLTYSIQ-SGNTDNVVAIESATGAL 867 Score = 260 bits (638), Expect = 3e-67 Identities = 176/522 (33%), Positives = 256/522 (49%), Gaps = 31/522 (5%) Query: 234 SPSRSNTTQLLINIRDVNDNAPRF-----YTSLFQESVSENVPIGYSIVRVQAYDADEGV 288 S S +N + I DVN++ P+F YT++ E + IG +I V A DAD G Sbjct: 364 SDSGTNGQFKMAIISDVNEHTPQFTSGGSYTAVIAEDAPDTA-IGVTIATVAATDADHGS 422 Query: 289 NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348 + +++ + GN + ID SG + LDRE+ Y L V A D G P +S+ Sbjct: 423 DGAISFAII----AGNEEDKFLIDTTSGVIELKRPLDRESTGSYILTVLARDHGSPNKSS 478 Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGG 406 A+ + VE+AE+ G+ V+ L D DE +++L Y IT G Sbjct: 479 NASVDVTVVDVNDNAPNCSVTAHVVEVAENASVGSTVLELRCEDVDEGANSQLTYNITTG 538 Query: 407 NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG-----RSDTAMVQINITD 461 T G++ V LD + Y L ++ D G R+ + I +TD Sbjct: 539 -----VDFTIDKSSGVVAVGSSLDRETRDLYELNITVRDRGNTEQERRAAVMQLTIEVTD 593 Query: 462 ANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521 N+ PVF YT ++ E+ G +V V+ TD D+GINA TYS++ + + Sbjct: 594 ENDNPPVFTQEIYTTTIPENMASGASVARVATTDRDIGINANHTYSITG---GDGLG--- 647 Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581 +F I TG IT LD ET Y L++TARD G P L V I + D NDN+PVF Sbjct: 648 -KFSIVQSTGVITALPGLDYETKYTYYLSITARDRGSPQLYAVAGVRIFLSDTNDNKPVF 706 Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641 LY +I E GT V V ATD D G+N I Y + D + F ++ ++G+IRT Sbjct: 707 SPTLYLTSISEATSAGTDVIPVHATDVDTGINAEITYSIVGGDAKN-QFSVN-STGMIRT 764 Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701 LDRE +A++ L A D G PPQ+ TV V + I D+ND+ VF + + E++P Sbjct: 765 IATLDREDIASYTLLVQASDRGVPPQTETVHVTVTILDVNDNAAVFSQSAFSARVLEDAP 824 Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 +G I A D D G NA + YSI+ G+ N ++E+ G+ Sbjct: 825 VGFRFMNISASDADSGDNARLTYSIQSGNTDNVVAIESATGA 866 Score = 249 bits (609), Expect = 1e-63 Identities = 172/497 (34%), Positives = 243/497 (48%), Gaps = 36/497 (7%) Query: 369 GQYEVELAEDEPP---GTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLI 423 G Y +AED P G + T+ ATDAD D + + I GN +F I + +G +I Sbjct: 391 GSYTAVIAEDAPDTAIGVTIATVAATDADHGSDGAISFAIIAGNEEDKFLIDTTSG--VI 448 Query: 424 TVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFED 481 + +PLD + Y+LTV A D G +S A V + + D N+ AP + V E+ Sbjct: 449 ELKRPLDRESTGSYILTVLARDHGSPNKSSNASVDVTVVDVNDNAPNCSVTAHVVEVAEN 508 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 A +G+TVL + D D G N+Q+TY++++ + F I+ +G + LDR Sbjct: 509 ASVGSTVLELRCEDVDEGANSQLTYNITTGVD----------FTIDKSSGVVAVGSSLDR 558 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDV---EISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 ET Y L +T RD G V I V D NDN PVF Q++YT I E+ G Sbjct: 559 ETRDLYELNITVRDRGNTEQERRAAVMQLTIEVTDENDNPPVFTQEIYTTTIPENMASGA 618 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 SV++V TD D+G+N Y + D G F I ++GVI LD E+ T+ L Sbjct: 619 SVARVATTDRDIGINANHTYSITGGDGL-GKFSIVQSTGVITALPGLDYETKYTYYLSIT 677 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 A D G+P + V I + D ND+ PVF ISE + GT + + A D D G Sbjct: 678 ARDRGSPQLYAVAGVRIFLSDTNDNKPVFSPTLYLTSISEATSAGTDVIPVHATDVDTGI 737 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLW 775 NA + YSI GGD N FS+ + + T+ LD E Y L+++A+ PP Sbjct: 738 NAEITYSIVGGDAKNQFSVNST-----GMIRTIATLDREDIAS-YTLLVQASDRGVPPQT 791 Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTD--KLQYRIL 832 V V + + DVNDNA V +D PVG F + A DAD D +L Y I Sbjct: 792 ETVHVTVTILDVNDNAAVFSQSAFSARVLEDA-PVGFRFMNISASDADSGDNARLTYSIQ 850 Query: 833 SGNNANLILLNETTGSM 849 SGN N++ + TG++ Sbjct: 851 SGNTDNVVAIESATGAL 867 Score = 239 bits (586), Expect = 6e-61 Identities = 169/517 (32%), Positives = 247/517 (47%), Gaps = 45/517 (8%) Query: 13 VLDCNDHSPVFEMQ-QYEASVREGASS---GTTVLTLKATDQDIGKNAEVEYTIELVTAD 68 + D N+H+P F Y A + E A G T+ T+ ATD D G + + + I Sbjct: 377 ISDVNEHTPQFTSGGSYTAVIAEDAPDTAIGVTIATVAATDADHGSDGAISFAI------ 430 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 +D F ID SG + + LDRE Y + V A D SP Sbjct: 431 -------------IAGNEEDKFLIDTTSGVIELKRPLDRESTGSYILTVLARDHGSP--- 474 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 SS A++ V ++D NDN P S + V V E+ SV + +++ D D GANS + Sbjct: 475 NKSSNASVDVTVVDVNDNAPNCSVTAHVVEVAENASV--GSTVLELRCEDVDEGANSQLT 532 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS---RSNTTQLLI 245 Y I T + F+ID SG V++ +LD E Y L I +D G+ R+ QL I Sbjct: 533 YNI---TTGVDFTIDKSSGVVAVGSSLDRETRDLYELNITVRDRGNTEQERRAAVMQLTI 589 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 + D NDN P F ++ ++ EN+ G S+ RV D D G+NA TY++T D G Sbjct: 590 EVTDENDNPPVFTQEIYTTTIPENMASGASVARVATTDRDIGINANHTYSITGGDGLGK- 648 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 +I +G + LD ET+ Y L +TA D G P A A Sbjct: 649 ---FSIVQSTGVITALPGLDYETKYTYYLSITARDRGSPQLYAVAGVRIFLSDTNDNKPV 705 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLI 423 F P Y ++E GT V+ + ATD D + + Y I GG+ + +FS+ N G+I Sbjct: 706 FSPTLYLTSISEATSAGTDVIPVHATDVDTGINAEITYSIVGGDAKNQFSV---NSTGMI 762 Query: 424 TVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 LD + Y L V A+D G +++T V + I D N+ A VF + ++A V ED Sbjct: 763 RTIATLDREDIASYTLLVQASDRGVPPQTETVHVTVTILDVNDNAAVFSQSAFSARVLED 822 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518 AP+G + +SA+D+D G NA++TYS+ S ++ VA Sbjct: 823 APVGFRFMNISASDADSGDNARLTYSIQSGNTDNVVA 859 Score = 202 bits (493), Expect = 1e-49 Identities = 131/411 (31%), Positives = 201/411 (48%), Gaps = 31/411 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V+D ND++P + + V E AS G+TVL L+ D D G N+++ Y I T Sbjct: 484 VTVVDVNDNAPNCSVTAHVVEVAENASVGSTVLELRCEDVDEGANSQLTYNI------TT 537 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F ID SG + +SLDRE Y + + D+ + +R Sbjct: 538 GVD----------------FTIDKSSGVVAVGSSLDRETRDLYELNITVRDRGNTEQERR 581 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 ++ + + + D+NDN P F+++ YT ++ E+++ +A++ TD D+G N+ Y+ Sbjct: 582 AAVMQLTIEVTDENDNPPVFTQEIYTTTIPENMA--SGASVARVATTDRDIGINANHTYS 639 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I GG+ +FSI +G ++ + LDYE +Y L I A+D GSP + I + D Sbjct: 640 ITGGDGLGKFSIVQSTGVITALPGLDYETKYTYYLSITARDRGSPQLYAVAGVRIFLSDT 699 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F +L+ S+SE G ++ V A D D G+NAE+TY++ D + T Sbjct: 700 NDNKPVFSPTLYLTSISEATSAGTDVIPVHATDVDTGINAEITYSIVGGDAKNQFSVNST 759 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 G + T LDRE A Y LLV A+D G PP++ T F Sbjct: 760 -----GMIRTIATLDREDIASYTLLVQASDRGVPPQTETVHVTVTILDVNDNAAVFSQSA 814 Query: 371 YEVELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRGRFSITSQNG 419 + + ED P G + ++A+DAD DN RL Y I GNT +I S G Sbjct: 815 FSARVLEDAPVGFRFMNISASDADSGDNARLTYSIQSGNTDNVVAIESATG 865 Score = 177 bits (432), Expect = 3e-42 Identities = 123/401 (30%), Positives = 197/401 (49%), Gaps = 37/401 (9%) Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ-YEVELAEDEPPG 382 L+ ET +Y L + A+DGG P +++T F+P YE+ LAED G Sbjct: 1 LNYETTMRYTLSIQASDGGTPGKASTTLAVIDVQGVNEYTPSFIPNNTYELSLAEDLSVG 60 Query: 383 TPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 V+ +TA+DAD ++ + G F++++ G++++A LD++ R Y L +S Sbjct: 61 HDVILVTASDADAGSQGEDAFIFLSVTGNFNVSTA---GVVSLATALDYESTRLYSLVLS 117 Query: 443 ATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 TDSG + + + + +T N ++PVF + A + +GT++ + TDSD+G Sbjct: 118 VTDSGLSTKSTQISVKVTVIAVNEFSPVFTSGGTYAVT--NTTVGTSITQLQCTDSDLGT 175 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560 NA ++YS++ N F ++ +G +TT K LD ET Y +T+ ARD Sbjct: 176 NAALSYSITDGDPNSV-------FTVS-SSGELTTVKQLDYETTQSYAITIQARDTSASQ 227 Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620 L + V++ V +N+ P F Q Y I E +GT+ G + Y + Sbjct: 228 LMAVSHVDVIVQALNEYTPSFSQSEYNVTISEATPIGTT--------------GELTYSM 273 Query: 621 DPKDREEGS-FVIDPASGVIRTNKALDRESVATHDLKAVAIDG-GTPPQSSTVIVHIKIE 678 GS F ID SGVI + LD E+V ++ L A DG + P+SS V V + ++ Sbjct: 274 P-----SGSPFYIDSLSGVITLKQGLDYEAVTSYVLLVTATDGDASSPKSSMVNVTVTVK 328 Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 D ND+ P F + I EN+ +GT+I + D D G N Sbjct: 329 DENDNEPTFTPAVYSVVIPENTTVGTSILSLTCTDSDSGTN 369 Score = 171 bits (415), Expect = 3e-40 Identities = 123/408 (30%), Positives = 197/408 (48%), Gaps = 44/408 (10%) Query: 215 LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY-TSLFQESVSENVPIG 273 L+YE Y L I+A DGG+P +++TT +I+++ VN+ P F + ++ S++E++ +G Sbjct: 1 LNYETTMRYTLSIQASDGGTPGKASTTLAVIDVQGVNEYTPSFIPNNTYELSLAEDLSVG 60 Query: 274 YSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQ 333 + ++ V A DAD G E + TGN ++ +G V + LD E+ Y Sbjct: 61 HDVILVTASDADAGSQGEDAFIFLS--VTGNFNVST-----AGVVSLATALDYESTRLYS 113 Query: 334 LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG-QYEVELAEDEPPGTPVVTLTATD 392 L+++ TD G +S + F G Y V + GT + L TD Sbjct: 114 LVLSVTDSGLSTKSTQISVKVTVIAVNEFSPVFTSGGTYAVT---NTTVGTSITQLQCTD 170 Query: 393 AD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS 450 +D + L Y IT G+ F+++S G +T + LD++ + Y +T+ A D+ Sbjct: 171 SDLGTNAALSYSITDGDPNSVFTVSSS---GELTTVKQLDYETTQSYAITIQARDTSASQ 227 Query: 451 DTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508 A+ V + + N Y P F + Y ++ E PIGTT ++TYS+ Sbjct: 228 LMAVSHVDVIVQALNEYTPSFSQSEYNVTISEATPIGTT--------------GELTYSM 273 Query: 509 SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS-LSDTTDV 567 S F I+ +G IT + LD E ++ Y+L VTA DG S S +V Sbjct: 274 PS----------GSPFYIDSLSGVITLKQGLDYEAVTSYVLLVTATDGDASSPKSSMVNV 323 Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615 ++V D NDNEP F +Y+ I E+ VGTS+ + TD+D G NG+ Sbjct: 324 TVTVKDENDNEPTFTPAVYSVVIPENTTVGTSILSLTCTDSDSGTNGQ 371 Score = 160 bits (389), Expect = 4e-37 Identities = 139/457 (30%), Positives = 221/457 (48%), Gaps = 46/457 (10%) Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQF-SEKTYTVSVDEDI 163 L+ E RYT+ ++A+D +P + S+T + +++ N+ P F TY +S+ ED+ Sbjct: 1 LNYETTMRYTLSIQASDGGTP--GKASTTLAV-IDVQGVNEYTPSFIPNNTYELSLAEDL 57 Query: 164 SVTDNPVIAKIKATDADVGANS--AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVR 221 SV + ++ + A+DAD G+ A + + GN F++ S +G VSL LDYE R Sbjct: 58 SVGHDVIL--VTASDADAGSQGEDAFIFLSVTGN----FNV-STAGVVSLATALDYESTR 110 Query: 222 SYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA 281 Y LV+ D G ++S + + + VN+ +P F TS +V+ N +G SI ++Q Sbjct: 111 LYSLVLSVTDSGLSTKSTQISVKVTVIAVNEFSPVF-TSGGTYAVT-NTTVGTSITQLQC 168 Query: 282 YDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341 D+D G NA L+Y++TD G+ + T+ SG + T QLD ET Y + + A D Sbjct: 169 TDSDLGTNAALSYSITD----GDPNSVFTVSS-SGELTTVKQLDYETTQSYAITIQARDT 223 Query: 342 GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHY 401 A + F +Y V ++E P GT L Y Sbjct: 224 SASQLMAVSHVDVIVQALNEYTPSFSQSEYNVTISEATPIGTT------------GELTY 271 Query: 402 EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSD-TAMVQINIT 460 + G+ F I S +G +IT+ Q LD++ YVL V+ATD S ++MV + +T Sbjct: 272 SMPSGSP---FYIDSLSG--VITLKQGLDYEAVTSYVLLVTATDGDASSPKSSMVNVTVT 326 Query: 461 --DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518 D N+ P F A Y+ + E+ +GT++L ++ TDSD G N Q ++ S++ NE Sbjct: 327 VKDENDNEPTFTPAVYSVVIPENTTVGTSILSLTCTDSDSGTNGQFKMAIISDV-NE--- 382 Query: 519 HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555 H QF A+ D + + TV A D Sbjct: 383 -HTPQFTSGGSYTAVIAEDAPD-TAIGVTIATVAATD 417 Score = 129 bits (311), Expect = 1e-27 Identities = 121/448 (27%), Positives = 200/448 (44%), Gaps = 56/448 (12%) Query: 11 INVLDCNDHSPVF-EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 I+V N+++P F YE S+ E S G V+ + A+D D G E + VT + Sbjct: 31 IDVQGVNEYTPSFIPNNTYELSLAEDLSVGHDVILVTASDADAGSQGEDAFIFLSVTGN- 89 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 F + +G + +LD E Y++++ TD S +S + Sbjct: 90 --------------------FNVS-TAGVVSLATALDYESTRLYSLVLSVTD--SGLSTK 126 Query: 130 LSSTATIHVNIIDDNDNYPQF-SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 S+ ++ V +I N+ P F S TY V+ + T I +++ TD+D+G N+A+ Sbjct: 127 -STQISVKVTVIAVNEFSPVFTSGGTYAVT-----NTTVGTSITQLQCTDSDLGTNAALS 180 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y+I G+ F++ S SG+++ VK LDYE +SY + I+A+D + + + + ++ Sbjct: 181 YSITDGDPNSVFTVSS-SGELTTVKQLDYETTQSYAITIQARDTSASQLMAVSHVDVIVQ 239 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 +N+ P F S + ++SE PI G ELTY+M +G+ P Sbjct: 240 ALNEYTPSFSQSEYNVTISEATPI--------------GTTGELTYSMP----SGS---P 278 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG-GDPPRSATATXXXXXXXXXXXXXXFM 367 ID SG + LD E Y LLVTATDG P+S+ F Sbjct: 279 FYIDSLSGVITLKQGLDYEAVTSYVLLVTATDGDASSPKSSMVNVTVTVKDENDNEPTFT 338 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT-GGNTRGRFSITSQNGRGLITVA 426 P Y V + E+ GT +++LT TD+D +++ + + G +A Sbjct: 339 PAVYSVVIPENTTVGTSILSLTCTDSDSGTNGQFKMAIISDVNEHTPQFTSGGSYTAVIA 398 Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAM 454 + + TV+ATD+ SD A+ Sbjct: 399 EDAPDTAIGVTIATVAATDADHGSDGAI 426 Score = 114 bits (274), Expect = 4e-23 Identities = 100/339 (29%), Positives = 156/339 (46%), Gaps = 33/339 (9%) Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF-KQQLYTANIMEDALVG 597 L+ ET Y L++ A DGG P + TT I V VN+ P F Y ++ ED VG Sbjct: 1 LNYETTMRYTLSIQASDGGTPGKASTTLAVIDVQGVNEYTPSFIPNNTYELSLAEDLSVG 60 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 V V A+DAD G G + G+F + A GV+ ALD ES + L Sbjct: 61 HDVILVTASDADAGSQGEDAFIFLSVT---GNFNVSTA-GVVSLATALDYESTRLYSLVL 116 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 D G +S+ + V + + +N+ PVF S Y N+ +GT+I +++ D D G Sbjct: 117 SVTDSGLSTKSTQISVKVTVIAVNEFSPVFTSGGT--YAVTNTTVGTSITQLQCTDSDLG 174 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPL 774 NA + YSI GD ++ F++ S EL T+ LDYE+ + Y + I+A ++ L Sbjct: 175 TNAALSYSITDGDPNSVFTV-----SSSGELTTVKQLDYET-TQSYAITIQARDTSASQL 228 Query: 775 WNDVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVGPFGRVPAYDADVTDKLQYRILS 833 V+++V +N+ P Q +N + P+G T +L Y + S Sbjct: 229 MAVSHVDVIVQALNEYTPSFS--QSEYNVTISEATPIG-----------TTGELTYSMPS 275 Query: 834 GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 G+ ++ +G +TL L+ + V+ TDG Sbjct: 276 GSP---FYIDSLSGVITLKQGLDYEAVTSYVLLVTATDG 311 Score = 101 bits (241), Expect = 4e-19 Identities = 71/198 (35%), Positives = 103/198 (52%), Gaps = 25/198 (12%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I + D ND+ PVF Y S+ E S+GT V+ + ATD D G NAE+ Y+I V D Sbjct: 693 RIFLSDTNDNKPVFSPTLYLTSISEATSAGTDVIPVHATDVDTGINAEITYSI--VGGDA 750 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N F ++ +G + T A+LDRE +A YT+LV+A+D+ P Sbjct: 751 KNQ-----------------FSVNS-TGMIRTIATLDREDIASYTLLVQASDRGVPPQ-- 790 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + T + V I+D NDN FS+ ++ V ED V I A+DAD G N+ + Y Sbjct: 791 -TETVHVTVTILDVNDNAAVFSQSAFSARVLEDAPVGFR--FMNISASDADSGDNARLTY 847 Query: 190 AIIGGNTQMQFSIDSLSG 207 +I GNT +I+S +G Sbjct: 848 SIQSGNTDNVVAIESATG 865 Score = 48.0 bits (109), Expect = 0.004 Identities = 21/64 (32%), Positives = 34/64 (53%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 +H + +LD ND++ VF + A V E A G + + A+D D G NA + Y+I+ Sbjct: 794 VHVTVTILDVNDNAAVFSQSAFSARVLEDAPVGFRFMNISASDADSGDNARLTYSIQSGN 853 Query: 67 ADTL 70 D + Sbjct: 854 TDNV 857 >UniRef50_UPI0000E7FFCA Cluster: PREDICTED: similar to FAT tumor suppressor homolog 4; n=5; Gallus gallus|Rep: PREDICTED: similar to FAT tumor suppressor homolog 4 - Gallus gallus Length = 2498 Score = 293 bits (718), Expect = 6e-77 Identities = 258/890 (28%), Positives = 407/890 (45%), Gaps = 75/890 (8%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 D ND+ PVF +YE SV E + G+ +LT+ ATD D G NA V+Y I T +P Sbjct: 738 DVNDNPPVFSSSRYEVSVPEDKARGSELLTVSATDLDAGANALVKYRIISQQPLTSSP-- 795 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134 VF ++ +G LD E ++ V ++A+D P L+++ Sbjct: 796 --------------VFLVNLTTGQFFLSQKLDYETTKQFEVELEASDGGQP---SLNTST 838 Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194 + ++++D NDN P+F++ TY + V E+I +PV TD D S + Sbjct: 839 HVVIHVLDVNDNPPKFNQVTYDIVVFENIQ-KGSPVCT-FSVTDDDEAGFSQGHFI---- 892 Query: 195 NTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252 + F++D + G +SL LD E + L + A D ++++ I + DVND Sbjct: 893 HNSTFFTVD-IPGIISLRNDTELDRETTPGFTLQVWAVDAEKDGLNSSSLFHITVLDVND 951 Query: 253 NAPRFYTSLFQESVSE-NVPIGYSIV--RVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 N P F + +V E + +G V V A D DEG NA +TY ++ +D D+ Sbjct: 952 NNPEFQMQSYSFAVLEGDYRLGAPAVVGHVTATDLDEGENARITYYLSSEDGDNPYDIQ- 1010 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 + G + +G +DRET+ KY+LL+ A+D G P R F Sbjct: 1011 ----QDGTILVNGCVDRETKEKYELLLVASDNGMPRRQNFTYISIQVLDVNDNVPQFTKV 1066 Query: 370 QYEVEL-AEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 Y + G V++++ATD D N + N F I + G +I ++ Sbjct: 1067 HYAASIPVATAKEGAFVLSVSATDLDIGNNSVISYSLMNHSDIFHINNHTGE-IILLSSL 1125 Query: 429 LDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 + LTV A D G S+ ++ + + + FE++ Y ++ E+ P+ Sbjct: 1126 AHVTADMVVTLTVIAADHGVPPLASNASVAVCLLVNDTGFGLAFESSRYEFNIPEEEPVR 1185 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 T V V A + I Q+ Y L S H +F I+ Q G I T LDRE + Sbjct: 1186 TVVGSVKALTGSIAI--QVVYFLRS---------HTDKFAISDQ-GDIVTLATLDREDDN 1233 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 Y + V A D VP + V + V D+NDN PVF + + T + + + + A Sbjct: 1234 LYNIVVEAVDSVVPPNTAIALVTVIVNDINDNPPVFSELIQTKLSLPENMAPLDLGTFSA 1293 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 TD D+G N I Y L G F I+ ++G + T +LDRE + ++LK +AID G P Sbjct: 1294 TDLDIGDNAFISYYLQYDFA--GMFHINTSTGKLMTGMSLDREMMDNYELKIIAIDSGKP 1351 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 P S+++ + I +ED+ND+ PV + + EN P I A D D G NAV+ Y+ Sbjct: 1352 PLSASLALSIAVEDVNDNSPVLSQKLYSVTVKENDP-PHVILSTTATDKDIGYNAVIQYT 1410 Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEI 782 I G SF + G + T+ LDYES Y ++A P L + + + Sbjct: 1411 IIG---ETSFHV----GELSGNISTVQPLDYES-CAHYTFTLKAFNPGEPHLQDTTNITV 1462 Query: 783 LVTDVNDNAPVMKD---FQIIF-NNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNAN 838 +V DVN+ P+ FQI+ N+ V R + D + + Y I GN+ Sbjct: 1463 IVEDVNEEGPMFDKPSYFQILLDNSTAGTLVVDIDARDESKGYD--EGIFYNITDGNSEG 1520 Query: 839 LILLNETTGSMTLSPQLNTNV-PKLATMEVSVTD-GVNEIKAMMQLSVRL 886 L L+ T+G +TL+ LN P ++ V+ TD G+ + +++SV + Sbjct: 1521 LFNLSSTSGVLTLTRDLNKQAFPLYNSLTVTATDSGLPPLSTSVKVSVTI 1570 Score = 277 bits (680), Expect = 2e-72 Identities = 252/896 (28%), Positives = 405/896 (45%), Gaps = 76/896 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND+ PV Y S+ E +G VL ++A D+D G + T L AD+ Sbjct: 327 VTIEDVNDNLPVLSQSSYNVSILENFPNGKEVLRIEAVDKDEGG---FQGTFSLTPADS- 382 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS--LDREKVARYTVLVKATDQASPVSD 128 F+I + G L R S LDRE+ + V A D SP + Sbjct: 383 ------------------PFQIS-QDGILTVRNSTLLDREQTPSIHLQVTARDHLSPYDE 423 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 S+ I+V ++D+NDN P F++ Y + I++T I ++ A D D G N AI Sbjct: 424 AQSA---INVLLLDENDNNPTFTDTQYEQVIF--INMTAGMSILQVAADDPDDGINGAIS 478 Query: 189 YAIIGGNTQMQFSIDSLSGDVSL--VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 + + GGN F +D +G +SL V L + +++ L + A DGG+ RS++ ++ Sbjct: 479 FVLAGGNEDGYFELDKSTGQISLKAVIPLRVNESKNFVLWVTATDGGTNPRSSSVP--VH 536 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 I V D+ P+F + SV E + + RV+ E +N + + + D Sbjct: 537 IFAVGDSRPQFIQKTYNVSVEEELVSPVEVARVKY----ESLNPHIPVILRVLTESATFD 592 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 + + +G ++T +LD E+Q Y L ++ +DG + AT F Sbjct: 593 VDV-----NGIIWTKIKLDFESQNNYTLNISLSDG---VTTDYATVFIQVTDVNDNSPVF 644 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 +++ E+ GT V ++ ATD D T G+ I + GLI + Sbjct: 645 GITNTTIKILENTAAGTSVTSVPATDVDTGFNGLVVYTLKGAEGKMDI---DASGLILLK 701 Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYAPVFENAPYTASVFEDAPI 484 + LD + + Y L V A+D G +A++ + I D N+ PVF ++ Y SV ED Sbjct: 702 KELDRETQGIYNLAVIASDQGQPRLSAVLNLTVVIDDVNDNPPVFSSSRYEVSVPEDKAR 761 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 G+ +L VSATD D G NA + Y + IS + + F++N TG ++ LD ET Sbjct: 762 GSELLTVSATDLDAGANALVKYRI---ISQQPLT-SSPVFLVNLTTGQFFLSQKLDYETT 817 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 + + + A DGG PSL+ +T V I V+DVNDN P F Q Y + E+ G+ V Sbjct: 818 KQFEVELEASDGGQPSLNTSTHVVIHVLDVNDNPPKFNQVTYDIVVFENIQKGSPVCTFS 877 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVID-PASGVIRTNKALDRESVATHDLKAVAIDGG 663 TD D + H+ F +D P +R + LDRE+ L+ A+D Sbjct: 878 VTDDDEAGFSQGHF-----IHNSTFFTVDIPGIISLRNDTELDRETTPGFTLQVWAVDAE 932 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS-PIG--TTIGEIRAHDPDEGPNA 720 +S+ + HI + D+ND+ P F+ +F + E +G +G + A D DEG NA Sbjct: 933 KDGLNSSSLFHITVLDVNDNNPEFQMQSYSFAVLEGDYRLGAPAVVGHVTATDLDEGENA 992 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWND 777 + Y + D N + ++ D LV +D E+ ++KYEL++ A+ P N Sbjct: 993 RITYYLSSEDGDNPYDIQ----QDGTILVNGC-VDRET-KEKYELLLVASDNGMPRRQNF 1046 Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVTDKLQYRILSGNN 836 + I V DVNDN P + G F V A D D+ + N+ Sbjct: 1047 TYISIQVLDVNDNVPQFTKVHYAASIPVATAKEGAFVLSVSATDLDIGNNSVISYSLMNH 1106 Query: 837 ANLILLNETTGSMTLSPQL-NTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEE 890 +++ +N TG + L L + + T+ V D GV + + ++V L+ + Sbjct: 1107 SDIFHINNHTGEIILLSSLAHVTADMVVTLTVIAADHGVPPLASNASVAVCLLVND 1162 Score = 262 bits (643), Expect = 7e-68 Identities = 233/808 (28%), Positives = 375/808 (46%), Gaps = 61/808 (7%) Query: 96 SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155 +G + T+ LD E YT+ + +D + + AT+ + + D NDN P F Sbjct: 596 NGIIWTKIKLDFESQNNYTLNISLSDGVT------TDYATVFIQVTDVNDNSPVFGITNT 649 Query: 156 TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTL 215 T+ + E+ + + + + ATD D G N + Y + G +M ID+ SG + L K L Sbjct: 650 TIKILENTAAGTS--VTSVPATDVDTGFNGLVVYTLKGAEGKMD--IDA-SGLILLKKEL 704 Query: 216 DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275 D E Y L + A D G P S L + I DVNDN P F +S ++ SV E+ G Sbjct: 705 DRETQGIYNLAVIASDQGQPRLSAVLNLTVVIDDVNDNPPVFSSSRYEVSVPEDKARGSE 764 Query: 276 IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL 335 ++ V A D D G NA + Y + + + + ++ +G + S +LD ET ++++ Sbjct: 765 LLTVSATDLDAGANALVKYRIISQQPLTSSPV-FLVNLTTGQFFLSQKLDYETTKQFEVE 823 Query: 336 VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395 + A+DGG P + + F Y++ + E+ G+PV T + TD DE Sbjct: 824 LEASDGGQPSLNTSTHVVIHVLDVNDNPPKFNQVTYDIVVFENIQKGSPVCTFSVTDDDE 883 Query: 396 DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR--YVLTVSATDS--GGRSD 451 + G+ + + + G+I++ + +E + L V A D+ G + Sbjct: 884 AG-----FSQGHFIHNSTFFTVDIPGIISLRNDTELDRETTPGFTLQVWAVDAEKDGLNS 938 Query: 452 TAMVQINITDANNYAPVFENAPYTASVFE-DAPIGTTVLV--VSATDSDVGINAQITYSL 508 +++ I + D N+ P F+ Y+ +V E D +G +V V+ATD D G NA+ITY L Sbjct: 939 SSLFHITVLDVNDNNPEFQMQSYSFAVLEGDYRLGAPAVVGHVTATDLDEGENARITYYL 998 Query: 509 SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568 SSE + +D Q Q G I N +DRET Y L + A D G+P + T + Sbjct: 999 SSEDGDNP---YDIQ-----QDGTILVNGCVDRETKEKYELLLVASDNGMPRRQNFTYIS 1050 Query: 569 ISVVDVNDNEPVFKQQLYTANI-MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627 I V+DVNDN P F + Y A+I + A G V V ATD D+G N I Y L Sbjct: 1051 IQVLDVNDNVPQFTKVHYAASIPVATAKEGAFVLSVSATDLDIGNNSVISYSL---MNHS 1107 Query: 628 GSFVIDPASGVIRTNKALDRESV-ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS--P 684 F I+ +G I +L + L +A D G PP +S V + + +ND+ Sbjct: 1108 DIFHINNHTGEIILLSSLAHVTADMVVTLTVIAADHGVPPLASNASVAVCLL-VNDTGFG 1166 Query: 685 PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV-VHYSIKGGDDSNSFSLETRQGS 743 FES F I E P+ T +G ++A G A+ V Y ++ D F++ S Sbjct: 1167 LAFESSRYEFNIPEEEPVRTVVGSVKAL---TGSIAIQVVYFLRSHTD--KFAI-----S 1216 Query: 744 DKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKD-FQI 799 D+ ++VT+ LD E Y +V+ A PP V ++V D+NDN PV + Q Sbjct: 1217 DQGDIVTLATLDREDD-NLYNIVVEAVDSVVPPNTAIALVTVIVNDINDNPPVFSELIQT 1275 Query: 800 IFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTLSPQLNT 857 + ++ P+ G A D D+ D + Y L + A + +N +TG + L+ Sbjct: 1276 KLSLPENMAPL-DLGTFSATDLDIGDNAFISY-YLQYDFAGMFHINTSTGKLMTGMSLDR 1333 Query: 858 NVPKLATME-VSVTDGVNEIKAMMQLSV 884 + ++ +++ G + A + LS+ Sbjct: 1334 EMMDNYELKIIAIDSGKPPLSASLALSI 1361 Score = 257 bits (630), Expect = 3e-66 Identities = 258/947 (27%), Positives = 420/947 (44%), Gaps = 83/947 (8%) Query: 13 VLDCNDHSPVF-EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71 V D ND+ PVF E+ Q + S+ E + + T ATD DIG NA + Y ++ A Sbjct: 1259 VNDINDNPPVFSELIQTKLSLPENMAP-LDLGTFSATDLDIGDNAFISYYLQYDFAG--- 1314 Query: 72 PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131 +F I+ +G L+T SLDRE + Y + + A D P LS Sbjct: 1315 -----------------MFHINTSTGKLMTGMSLDREMMDNYELKIIAIDSGKPP---LS 1354 Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP-VIAKIKATDADVGANSAIRYA 190 ++ + + + D NDN P S+K Y+V+V E+ D P VI ATD D+G N+ I+Y Sbjct: 1355 ASLALSIAVEDVNDNSPVLSQKLYSVTVKEN----DPPHVILSTTATDKDIGYNAVIQYT 1410 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 IIG + F + LSG++S V+ LDYE Y ++A + G P +TT + + + DV Sbjct: 1411 IIG---ETSFHVGELSGNISTVQPLDYESCAHYTFTLKAFNPGEPHLQDTTNITVIVEDV 1467 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 N+ P F + + + +N G +V + A D +G + + Y +TD GN + Sbjct: 1468 NEEGPMFDKPSYFQILLDNSTAGTLVVDIDARDESKGYDEGIFYNITD----GNSEGLFN 1523 Query: 311 IDPRSGWVYTSGQLDRETQAKY-QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 + SG + + L+++ Y L VTATD G PP S + F Sbjct: 1524 LSSTSGVLTLTRDLNKQAFPLYNSLTVTATDSGLPPLSTSVKVSVTIAPTNISLPVFSEA 1583 Query: 370 QYE-VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 Y+ L+E P T VV +T + Y I G+ +G F I G I + Sbjct: 1584 VYQPAPLSEKTLPDTFVVQITVL---YKVPVVYSIVAGDEKGYFIINPST--GTIRTGKK 1638 Query: 429 LDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 L ++ V +V ATDS S + V + + D N++ PVF + + E+ P T Sbjct: 1639 LTV-EDSLIVFSVRATDSSTASIFNDVSVHVEVIDENDFPPVFTFSLLEQGLEENLP-AT 1696 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD-RETMS 545 ++ + A D+D G N +TY + +S + +F I+ TG + + D E + Sbjct: 1697 QIVHLIARDNDTGRNGDLTYGI---LSGDGT-----KFRIDESTGILYSTVSFDYEEEPT 1748 Query: 546 GYLLTVTARDGGVPSLS-DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 Y + + A D G P V + + DVND PVF + ++ E+ V V +V Sbjct: 1749 EYQVVIYAEDDGTPEKKRGYCTVVVKITDVNDWPPVF-NPVTPFSVNENVDVEFIVGKVT 1807 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 A D D G N + Y L F ID G I+ + D E+V + L A++ + Sbjct: 1808 AMDRDTGDNAFVLYSL--TGGGGNIFEIDALLGNIKIKNSPDYENVNKYTLTVTAVNNKS 1865 Query: 665 PP-QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 P +T V + + D+ND+ PVF + + I+ +P+G + + A D D+G N ++ Sbjct: 1866 APFYQATTNVTVLVIDVNDNAPVFAQNSYSTSINMINPVGVHVITVHATDKDQGQNGLIE 1925 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEIL 783 Y I D N + + + +++T +L ++ + P N V + Sbjct: 1926 YYII--PDLNFSAFFLIEDESEGKIITTGNLS-RFEEVCLTVMAKDKGSPSLNSTAV--I 1980 Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD-ADVTDKL-QYRILSGNNANLIL 841 +V DN P + F + G + + A+ + KL Y I+SGN Sbjct: 1981 TLNVIDNRPFVPRFSENKVSISVLENTGVDHSIYTFAVAETSGKLIVYTIVSGNEKGHFR 2040 Query: 842 LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVR-L 900 L+ +G L +N N +++ + V + A S L + + + +ITV+ + Sbjct: 2041 LDPKSGQ--LKTAINLNYEEVSQYVILVEANEDVSSAAQVPSSGLFAQNVAMLTITVQDV 2098 Query: 901 NDMTAEQFLSPLLGFFIDGLAAIIPCPKENIY-IFSVQ-DDTDVTGN 945 N+ A FL+ + +A+IP Y + +VQ D D GN Sbjct: 2099 NEKPA--FLNSM-------YSALIPSSVPYKYPVITVQATDPDAGGN 2136 Score = 256 bits (628), Expect = 5e-66 Identities = 231/817 (28%), Positives = 358/817 (43%), Gaps = 63/817 (7%) Query: 9 QQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKN-AEVEYTIELVTA 67 + + + D ND+SP F Y SV E ++ +TV+ ++A D+D+ + + Y++ Sbjct: 111 RDLQLEDVNDNSPEFLQALYNTSVSEVSAINSTVIKVEAQDKDLSPLFSHISYSL----- 165 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 L P D F I G ++ +LD K+ + + V A ++ Sbjct: 166 --LGPNS-------------DYFYIREGDGNIMVNKTLDYNKINHFNLTVLAKERFG--- 207 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 S+T ++ +++ D + P FS Y ++ E+ + + KI A D D G N + Sbjct: 208 -NNSNTVSLIIDVQDYDTLNPYFSLSVYNGTISENKLGPLSILPEKIFAKDGDTGINEKV 266 Query: 188 RYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 Y+I FSI + SG + + +D E+ + I A + ++ +L Sbjct: 267 YYSIKLVKPPAYSNTFSISADSGMLEVKTAVDREECPYLFVGIEAAQQDNNLKTADAVVL 326 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + I DVNDN P S + S+ EN P G ++R++A D DEG + T+++T D Sbjct: 327 VTIEDVNDNLPVLSQSSYNVSILENFPNGKEVLRIEAVDKDEG-GFQGTFSLTPADSPFQ 385 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 + + R+ S LDRE L VTA D P A + Sbjct: 386 ISQDGILTVRN-----STLLDREQTPSIHLQVTARDHLSPYDEAQSAINVLLLDENDNNP 440 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGL 422 F QYE + + G ++ + A D D+ + + + + GGN G F + G+ Sbjct: 441 TFTDTQYEQVIFINMTAGMSILQVAADDPDDGINGAISFVLAGGNEDGYFELDKSTGQIS 500 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 + PL + + +VL V+ATD G ++ V ++I + P F Y SV E+ Sbjct: 501 LKAVIPLRVNESKNFVLWVTATDGGTNPRSSSVPVHIFAVGDSRPQFIQKTYNVSVEEEL 560 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 V V +N I L ++ A D +N G I T LD E Sbjct: 561 VSPVEVARVKYE----SLNPHIPVIL-RVLTESATFDVD----VN---GIIWTKIKLDFE 608 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 + + Y L ++ DG +D V I V DVNDN PVF T I+E+ GTSV+ Sbjct: 609 SQNNYTLNISLSDG---VTTDYATVFIQVTDVNDNSPVFGITNTTIKILENTAAGTSVTS 665 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 V ATD D G NG + Y L EG ID ASG+I K LDRE+ ++L +A D Sbjct: 666 VPATDVDTGFNGLVVYTL---KGAEGKMDID-ASGLILLKKELDRETQGIYNLAVIASDQ 721 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 G P S+ + + + I+D+ND+PPVF S + E+ G+ + + A D D G NA+V Sbjct: 722 GQPRLSAVLNLTVVIDDVNDNPPVFSSSRYEVSVPEDKARGSELLTVSATDLDAGANALV 781 Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVR 779 Y I S S + LDYE+ K++E+ + A+ P L Sbjct: 782 KYRIISQQPLTS-SPVFLVNLTTGQFFLSQKLDYET-TKQFEVELEASDGGQPSLNTSTH 839 Query: 780 VEILVTDVNDNAPVMKDFQ---IIFNNYKDCFPVGPF 813 V I V DVNDN P ++F N + PV F Sbjct: 840 VVIHVLDVNDNPPKFNQVTYDIVVFENIQKGSPVCTF 876 Score = 218 bits (533), Expect = 2e-54 Identities = 209/749 (27%), Positives = 347/749 (46%), Gaps = 54/749 (7%) Query: 142 DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN-SAIRYAIIGGNTQMQF 200 D NDN P+F + Y SV E ++ N + K++A D D+ S I Y+++G N+ F Sbjct: 117 DVNDNSPEFLQALYNTSVSEVSAI--NSTVIKVEAQDKDLSPLFSHISYSLLGPNSDY-F 173 Query: 201 SIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260 I G++ + KTLDY ++ + L + A++ + SNT L+I+++D + P F S Sbjct: 174 YIREGDGNIMVNKTLDYNKINHFNLTVLAKERFG-NNSNTVSLIIDVQDYDTLNPYFSLS 232 Query: 261 LFQESVSENV--PIGYSIVRVQAYDADEGVNAELTYTM-TDKDYTGNVDLPITIDPRSGW 317 ++ ++SEN P+ ++ A D D G+N ++ Y++ K + I+ D SG Sbjct: 233 VYNGTISENKLGPLSILPEKIFAKDGDTGINEKVYYSIKLVKPPAYSNTFSISAD--SGM 290 Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377 + +DRE + + A + ++A A Y V + E Sbjct: 291 LEVKTAVDREECPYLFVGIEAAQQDNNLKTADAVVLVTIEDVNDNLPVLSQSSYNVSILE 350 Query: 378 DEPPGTPVVTLTATDADEDN-RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436 + P G V+ + A D DE + + +T ++ F I SQ+G + + LD +Q Sbjct: 351 NFPNGKEVLRIEAVDKDEGGFQGTFSLTPADS--PFQI-SQDGILTVRNSTLLDREQTPS 407 Query: 437 YVLTVSATDSGGRSDTAMVQINI--TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494 L V+A D D A IN+ D N+ P F + Y +F + G ++L V+A Sbjct: 408 IHLQVTARDHLSPYDEAQSAINVLLLDENDNNPTFTDTQYEQVIFINMTAGMSILQVAAD 467 Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET--MSGYLLTVT 552 D D GIN I++ L+ NE D F ++ TG I+ ++ ++L VT Sbjct: 468 DPDDGINGAISFVLAG--GNE-----DGYFELDKSTGQISLKAVIPLRVNESKNFVLWVT 520 Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612 A DGG S + V + + V D+ P F Q+ Y ++ E+ + V++V L Sbjct: 521 ATDGGTNPRS--SSVPVHIFAVGDSRPQFIQKTYNVSVEEELVSPVEVARVKYE----SL 574 Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672 N I L E +F +D +G+I T LD ES + L DG T ++ Sbjct: 575 NPHIPVILRVL-TESATFDVD-VNGIIWTKIKLDFESQNNYTLNISLSDGVTTDYAT--- 629 Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732 V I++ D+ND+ PVF T I EN+ GT++ + A D D G N +V Y++KG Sbjct: 630 VFIQVTDVNDNSPVFGITNTTIKILENTAAGTSVTSVPATDVDTGFNGLVVYTLKGA--- 686 Query: 733 NSFSLETRQGSDKAELVTM-VDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVN 788 E + D + L+ + +LD E+ + Y L + A+ P L + + +++ DVN Sbjct: 687 -----EGKMDIDASGLILLKKELDRET-QGIYNLAVIASDQGQPRLSAVLNLTVVIDDVN 740 Query: 789 DNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSG---NNANLILLN 843 DN PV + + +D V A D D ++YRI+S ++ + L+N Sbjct: 741 DNPPVFSSSRYEVSVPEDKARGSELLTVSATDLDAGANALVKYRIISQQPLTSSPVFLVN 800 Query: 844 ETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 TTG LS +L+ K +E+ +DG Sbjct: 801 LTTGQFFLSQKLDYETTKQFEVELEASDG 829 Score = 212 bits (518), Expect = 1e-52 Identities = 220/771 (28%), Positives = 336/771 (43%), Gaps = 75/771 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+SPV + Y +V+E +L+ ATD+DIG NA ++YTI T+ Sbjct: 1361 IAVEDVNDNSPVLSQKLYSVTVKEN-DPPHVILSTTATDKDIGYNAVIQYTIIGETS--- 1416 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F + SG + T LD E A YT +KA + P L Sbjct: 1417 -------------------FHVGELSGNISTVQPLDYESCAHYTFTLKAFNPGEP---HL 1454 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTY-TVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 T I V + D N+ P F + +Y + +D T ++ I A D G + I Y Sbjct: 1455 QDTTNITVIVEDVNEEGPMFDKPSYFQILLDNS---TAGTLVVDIDARDESKGYDEGIFY 1511 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR-LVIRAQDGGSPSRSNTTQLLINIR 248 I GN++ F++ S SG ++L + L+ + Y L + A D G P S + ++ + I Sbjct: 1512 NITDGNSEGLFNLSSTSGVLTLTRDLNKQAFPLYNSLTVTATDSGLPPLSTSVKVSVTIA 1571 Query: 249 DVNDNAPRFYTSLFQES-VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 N + P F +++Q + +SE +V++ + Y++ D G Sbjct: 1572 PTNISLPVFSEAVYQPAPLSEKTLPDTFVVQITVL-----YKVPVVYSIVAGDEKGY--- 1623 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 I+P +G + T +L E + V ATD + F Sbjct: 1624 -FIINPSTGTIRTGKKLTVE-DSLIVFSVRATDSSTASIFNDVSVHVEVIDENDFPPVFT 1681 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITV 425 E L E+ P T +V L A D D + L Y I G+ +F I G TV Sbjct: 1682 FSLLEQGL-EENLPATQIVHLIARDNDTGRNGDLTYGILSGDGT-KFRIDESTGILYSTV 1739 Query: 426 AQPLDFKQE-RRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 + D+++E Y + + A D G + V + ITD N++ PVF N SV E+ Sbjct: 1740 S--FDYEEEPTEYQVVIYAEDDGTPEKKRGYCTVVVKITDVNDWPPVF-NPVTPFSVNEN 1796 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 + V V+A D D G NA + YSL+ N F I+ G I D Sbjct: 1797 VDVEFIVGKVTAMDRDTGDNAFVLYSLTGGGGN--------IFEIDALLGNIKIKNSPDY 1848 Query: 542 ETMSGYLLTVTA-RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 E ++ Y LTVTA + P TT+V + V+DVNDN PVF Q Y+ +I VG V Sbjct: 1849 ENVNKYTLTVTAVNNKSAPFYQATTNVTVLVIDVNDNAPVFAQNSYSTSINMINPVGVHV 1908 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVI-DPASGVIRTNKALDR-ESVATHDLKAV 658 V ATD D G NG I Y + P F+I D + G I T L R E V L + Sbjct: 1909 ITVHATDKDQGQNGLIEYYIIPDLNFSAFFLIEDESEGKIITTGNLSRFEEVC---LTVM 1965 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 A D G+P +ST ++ + + D P F + ++ + EN+ + +I E Sbjct: 1966 AKDKGSPSLNSTAVITLNVIDNRPFVPRFSENKVSISVLENTGVDHSIYTFAV---AETS 2022 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 ++ Y+I G++ F L+ + G +L T ++L+YE +Y +++ A Sbjct: 2023 GKLIVYTIVSGNEKGHFRLDPKSG----QLKTAINLNYEEV-SQYVILVEA 2068 Score = 186 bits (452), Expect = 1e-44 Identities = 154/539 (28%), Positives = 244/539 (45%), Gaps = 59/539 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V+D ND PVF E + E + T ++ L A D D G+N ++ Y I ++ D Sbjct: 1668 VEVIDENDFPPVFTFSLLEQGLEENLPA-TQIVHLIARDNDTGRNGDLTYGI--LSGDGT 1724 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLD-REKVARYTVLVKATDQASPVSDR 129 FRID +G L + S D E+ Y V++ A D +P R Sbjct: 1725 K------------------FRIDESTGILYSTVSFDYEEEPTEYQVVIYAEDDGTPEKKR 1766 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 T+ V I D ND P F+ T SV+E++ V ++ K+ A D D G N+ + Y Sbjct: 1767 --GYCTVVVKITDVNDWPPVFNPVT-PFSVNENVDVEF--IVGKVTAMDRDTGDNAFVLY 1821 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS-PSRSNTTQLLINIR 248 ++ GG + F ID+L G++ + + DYE V Y L + A + S P TT + + + Sbjct: 1822 SLTGGGGNI-FEIDALLGNIKIKNSPDYENVNKYTLTVTAVNNKSAPFYQATTNVTVLVI 1880 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY-TMTDKDYTGNVDL 307 DVNDNAP F + + S++ P+G ++ V A D D+G N + Y + D +++ Sbjct: 1881 DVNDNAPVFAQNSYSTSINMINPVGVHVITVHATDKDQGQNGLIEYYIIPDLNFSAFF-- 1938 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 + D G + T+G L R + L V A D G P ++TA F Sbjct: 1939 -LIEDESEGKIITTGNLSRFEEVC--LTVMAKDKGSPSLNSTAVITLNVIDNRPFVPRFS 1995 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 + + + E+ + T + + Y I GN +G F + ++G+ + A Sbjct: 1996 ENKVSISVLENTGVDHSIYTFAVAETS-GKLIVYTIVSGNEKGHFRLDPKSGQ--LKTAI 2052 Query: 428 PLDFKQERRYVLTVSATD---------SGG--RSDTAMVQINITDANNYAPVFENAPYTA 476 L++++ +YV+ V A + S G + AM+ I + D N P F N+ Y+A Sbjct: 2053 NLNYEEVSQYVILVEANEDVSSAAQVPSSGLFAQNVAMLTITVQDVNE-KPAFLNSMYSA 2111 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 + P V+ V ATD D G N +TYSL +H +QF +N TG I T Sbjct: 2112 LIPSSVPYKYPVITVQATDPDAGGNGLLTYSL---------LNHQEQFDVNENTGQIYT 2161 Score = 184 bits (449), Expect = 2e-44 Identities = 190/732 (25%), Positives = 317/732 (43%), Gaps = 70/732 (9%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72 V D N+ P+F+ Y + + +++GT V+ + A D+ G + + Y I ++ L Sbjct: 1464 VEDVNEEGPMFDKPSYFQILLDNSTAGTLVVDIDARDESKGYDEGIFYNITDGNSEGL-- 1521 Query: 73 EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVL-VKATDQASPVSDRLS 131 F + SG L L+++ Y L V ATD P LS Sbjct: 1522 -----------------FNLSSTSGVLTLTRDLNKQAFPLYNSLTVTATDSGLPP---LS 1561 Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191 ++ + V I N + P FSE Y + + ++ D V+ V + Y+I Sbjct: 1562 TSVKVSVTIAPTNISLPVFSEAVYQPAPLSEKTLPDTFVV------QITVLYKVPVVYSI 1615 Query: 192 IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251 + G+ + F I+ +G + K L E +RA D + S N + + + D N Sbjct: 1616 VAGDEKGYFIINPSTGTIRTGKKLTVEDSLIV-FSVRATDSSTASIFNDVSVHVEVIDEN 1674 Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311 D P F SL ++ + EN+P IV + A D D G N +LTY + D T I Sbjct: 1675 DFPPVFTFSLLEQGLEENLP-ATQIVHLIARDNDTGRNGDLTYGILSGDGT-----KFRI 1728 Query: 312 DPRSGWVYTSGQLDRETQ-AKYQLLVTATDGGDPPRS-ATATXXXXXXXXXXXXXXFMPG 369 D +G +Y++ D E + +YQ+++ A D G P + T F P Sbjct: 1729 DESTGILYSTVSFDYEEEPTEYQVVIYAEDDGTPEKKRGYCTVVVKITDVNDWPPVFNPV 1788 Query: 370 QYEVELAEDEPPGTPVVTLTATDADE-DNR-LHYEITGGNTRGRFSITSQNGRGLITVAQ 427 + E+ V +TA D D DN + Y +TGG F I + G I + Sbjct: 1789 T-PFSVNENVDVEFIVGKVTAMDRDTGDNAFVLYSLTGGGGN-IFEIDALLGN--IKIKN 1844 Query: 428 PLDFKQERRYVLTVSATDSGGR---SDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 D++ +Y LTV+A ++ T V + + D N+ APVF Y+ S+ P+ Sbjct: 1845 SPDYENVNKYTLTVTAVNNKSAPFYQATTNVTVLVIDVNDNAPVFAQNSYSTSINMINPV 1904 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT-GAITTNKLLDRET 543 G V+ V ATD D G N I Y + +++ A F+I ++ G I T L R Sbjct: 1905 GVHVITVHATDKDQGQNGLIEYYIIPDLNFSAF------FLIEDESEGKIITTGNLSR-- 1956 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 LTV A+D G PSL+ T + ++V+D P F + + +++E+ V S+ Sbjct: 1957 FEEVCLTVMAKDKGSPSLNSTAVITLNVIDNRPFVPRFSENKVSISVLENTGVDHSIYTF 2016 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID-- 661 + +G++ E+G F +DP SG ++T L+ E V+ + + A + Sbjct: 2017 AVAET----SGKLIVYTIVSGNEKGHFRLDPKSGQLKTAINLNYEEVSQYVILVEANEDV 2072 Query: 662 --GGTPPQS-----STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 P S + ++ I ++D+N+ P F + + I + P + ++A DP Sbjct: 2073 SSAAQVPSSGLFAQNVAMLTITVQDVNEKP-AFLNSMYSALIPSSVPYKYPVITVQATDP 2131 Query: 715 DEGPNAVVHYSI 726 D G N ++ YS+ Sbjct: 2132 DAGGNGLLTYSL 2143 Score = 151 bits (365), Expect = 4e-34 Identities = 173/657 (26%), Positives = 282/657 (42%), Gaps = 52/657 (7%) Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYTG 303 + + DVNDN+P F +L+ SVSE I ++++V+A D D + + ++Y++ Sbjct: 113 LQLEDVNDNSPEFLQALYNTSVSEVSAINSTVIKVEAQDKDLSPLFSHISYSLLGP---- 168 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 N D I G + + LD + L V A + S T + Sbjct: 169 NSDY-FYIREGDGNIMVNKTLDYNKINHFNLTVLAKERFGN-NSNTVSLIIDVQDYDTLN 226 Query: 364 XXFMPGQYEVELAEDE--PPGTPVVTLTATDADE--DNRLHYEITGGNT---RGRFSITS 416 F Y ++E++ P + A D D + +++Y I FSI++ Sbjct: 227 PYFSLSVYNGTISENKLGPLSILPEKIFAKDGDTGINEKVYYSIKLVKPPAYSNTFSISA 286 Query: 417 QNGRGLITVAQPLDFKQERRYV---LTVSATDSGGRSDTAMVQINITDANNYAPVFENAP 473 +G ++ V +D ++E Y+ + + D+ ++ A+V + I D N+ PV + Sbjct: 287 DSG--MLEVKTAVD-REECPYLFVGIEAAQQDNNLKTADAVVLVTIEDVNDNLPVLSQSS 343 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 Y S+ E+ P G VL + A D D G Q T+SL+ D F I+ Q G + Sbjct: 344 YNVSILENFPNGKEVLRIEAVDKDEG-GFQGTFSLTPA---------DSPFQIS-QDGIL 392 Query: 534 TTNK--LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 T LLDRE L VTARD P + + + ++D NDN P F Y I Sbjct: 393 TVRNSTLLDREQTPSIHLQVTARDHLSPYDEAQSAINVLLLDENDNNPTFTDTQYEQVIF 452 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA 651 + G S+ QV A D D G+NG I + L E+G F +D ++G I + Sbjct: 453 INMTAGMSILQVAADDPDDGINGAISFVL-AGGNEDGYFELDKSTGQISLKAVIPLRVNE 511 Query: 652 THD--LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 + + L A DGGT P+SS+V VHI + DS P F T+ +S + + + Sbjct: 512 SKNFVLWVTATDGGTNPRSSSVPVHIFA--VGDSRPQFIQK--TYNVSVEEELVSPVEVA 567 Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 R P+ V + +S +F ++ + T + LD+ES + Y L I Sbjct: 568 RVKYESLNPHIPVILRVL--TESATFDVDV-----NGIIWTKIKLDFES-QNNYTLNISL 619 Query: 770 ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV-TDKLQ 828 + + V I VTDVNDN+PV ++ VPA D D + L Sbjct: 620 SDGVTTDYATVFIQVTDVNDNSPVFGITNTTIKILENTAAGTSVTSVPATDVDTGFNGLV 679 Query: 829 YRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSV 884 L G + + + +G + L +L+ + + V +D G + A++ L+V Sbjct: 680 VYTLKGAEGKMDI--DASGLILLKKELDRETQGIYNLAVIASDQGQPRLSAVLNLTV 734 Score = 81.4 bits (192), Expect = 3e-13 Identities = 83/264 (31%), Positives = 120/264 (45%), Gaps = 17/264 (6%) Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG-LNGRIHYELDPKDRE 626 ++ + DVNDN P F Q LY ++ E + + ++V +V A D D+ L I Y L + + Sbjct: 112 DLQLEDVNDNSPEFLQALYNTSVSEVSAINSTVIKVEAQDKDLSPLFSHISYSLLGPNSD 171 Query: 627 EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686 F I G I NK LD + +L +A + S+TV + I ++D + P Sbjct: 172 --YFYIREGDGNIMVNKTLDYNKINHFNLTVLAKE-RFGNNSNTVSLIIDVQDYDTLNPY 228 Query: 687 FESDCLTFYISEN--SPIGTTIGEIRAHDPDEGPNAVVHYSI---KGGDDSNSFSLETRQ 741 F ISEN P+ +I A D D G N V+YSI K SN+FS+ Sbjct: 229 FSLSVYNGTISENKLGPLSILPEKIFAKDGDTGINEKVYYSIKLVKPPAYSNTFSISADS 288 Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN-DVRVEILVTDVNDNAPVMKDFQII 800 G E+ T VD + E P + L D V + + DVNDN PV+ Q Sbjct: 289 G--MLEVKTAVDRE-ECPYLFVGIEAAQQDNNLKTADAVVLVTIEDVNDNLPVLS--QSS 343 Query: 801 FN-NYKDCFPVG-PFGRVPAYDAD 822 +N + + FP G R+ A D D Sbjct: 344 YNVSILENFPNGKEVLRIEAVDKD 367 Score = 37.9 bits (84), Expect = 4.0 Identities = 18/44 (40%), Positives = 22/44 (50%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD 51 H I+VLD ND+ P F Y+ V E G+ V T TD D Sbjct: 839 HVVIHVLDVNDNPPKFNQVTYDIVVFENIQKGSPVCTFSVTDDD 882 >UniRef50_A7RQ21 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 1888 Score = 288 bits (706), Expect = 2e-75 Identities = 230/812 (28%), Positives = 380/812 (46%), Gaps = 65/812 (8%) Query: 90 FRIDGRSGALLTRASLDRE--KVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 FR+D SG + R+ LD E K R+T + T + ++ + S A + + + D NDN Sbjct: 776 FRVDPYSGDVRVRSGLDYETVKTHRFTAEARNTRDNTDYAN-IDSEADVKIVLRDLNDNP 834 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 P+F E +Y ++ E V + + A D D G N Y + +Q FS+D +G Sbjct: 835 PEFFELSYRDTLPESAPV--GTTVLSVTARDLDSGVNGQFHYFV---ESQF-FSVDPYTG 888 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 ++ + LD+E ++ ++ AQD G+P+R+ T ++++ + +VNDNAPRF SL+ V+ Sbjct: 889 WITTKRPLDFETNPTHSFLVVAQDSGNPARNGTARVIVELTNVNDNAPRFSQSLYNVFVA 948 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV-YTSGQLDR 326 E+ + VQA D D N +TY++ D T N I+ ++G + S + Sbjct: 949 EDAGSDQLVATVQATDKD---NDPVTYSIASGDNTTN----FVINNKTGVIKLVSNRKPE 1001 Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386 Y + ++A+DG ++ Y + ED+PP T V+ Sbjct: 1002 LIGPYYTMNISASDGLHVSQAMVIVAIQDVNNHKPVFTDC--ASYHPVVMEDDPPNTFVM 1059 Query: 387 TLTATDAD--EDNRLHYEI-TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443 + A D D + + Y I F+I + G++T Q D +++ Y + + Sbjct: 1060 QVHADDQDTGANGEVIYSIEKPPGALSYFAIDDKT--GIVTTLQSFDREEKPVYQIRIIG 1117 Query: 444 TDSG-GRSDTA-------MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495 D G G S A V I I D N++ PVF+N Y A++ ED +G +VL VSATD Sbjct: 1118 RDGGLGSSRGAERLMGVCQVDIRIGDKNDHDPVFQNKQYEATIKEDFEVGRSVLHVSATD 1177 Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG------YLL 549 +D G NA++TYS+ + + F I+ TG +T+ L E S Sbjct: 1178 ADAGSNAKLTYSIQPQ---------NDYFAIDRATGTVTSKMSLLSEAKSEGQSSRVISF 1228 Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 V A D G S T V I+V+D+ ++ PVF Q +Y + ED +G+S+ Q+ A+ Sbjct: 1229 NVVANDNGNVSRKTVTLVRITVLDLGNDPPVFSQGVYVVTVREDIAIGSSLIQLSAS--- 1285 Query: 610 VGLNGRIHYEL----DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 N I+Y + P F I + G++ + LD + + L + + P Sbjct: 1286 TKTNKLIYYSIVPGNVPSSNNPPRFQIRISKGIVWNSHRLDHKETSNFSL-TIRAETTDP 1344 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 P S+ + I +ED+ND+PP F ++SEN+PIG+++ ++ A D D G N V YS Sbjct: 1345 PMSAFANLKIFLEDVNDNPPEFVMPRYQGHVSENAPIGSSVLQVSARDRDSGENGRVTYS 1404 Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEI 782 DS+ F L+ G + T + D E+ + +Y L ++A SP D VEI Sbjct: 1405 FVQDKDSDKFGLDENTGL----VTTREEFDREA-QGRYTLALKARDNGSPQKTTDTIVEI 1459 Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLI 840 ++TD NDN P+ ++ + + +V A D D V ++ Y I GN Sbjct: 1460 IITDENDNPPIFEEKVYNISVLESAASGMELLKVSAVDRDFGVNARVSYYISEGNINGAF 1519 Query: 841 LLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 +N G++ L+ L+ + ++ DG Sbjct: 1520 EVNREFGTIRLAGTLDRENVDHYKLTLTAKDG 1551 Score = 287 bits (703), Expect = 4e-75 Identities = 234/798 (29%), Positives = 372/798 (46%), Gaps = 65/798 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I + D ND+ P F Y ++ E A GTTVL++ A D D G N + Y +E Sbjct: 824 KIVLRDLNDNPPEFFELSYRDTLPESAPVGTTVLSVTARDLDSGVNGQFHYFVE------ 877 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 F +D +G + T+ LD E ++ LV A D +P + Sbjct: 878 -----------------SQFFSVDPYTGWITTKRPLDFETNPTHSFLVVAQDSGNPARN- 919 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 TA + V + + NDN P+FS+ Y V V ED + ++A ++ATD D N + Y Sbjct: 920 --GTARVIVELTNVNDNAPRFSQSLYNVFVAEDAG--SDQLVATVQATDKD---NDPVTY 972 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLV-IRAQDGGSPSRSNTTQLLINIR 248 +I G+ F I++ +G + LV E + Y + I A DG S++ +++ I+ Sbjct: 973 SIASGDNTTNFVINNKTGVIKLVSNRKPELIGPYYTMNISASDGLHVSQA---MVIVAIQ 1029 Query: 249 DVNDNAPRFYT-SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 DVN++ P F + + V E+ P +++V A D D G N E+ Y++ G + Sbjct: 1030 DVNNHKPVFTDCASYHPVVMEDDPPNTFVMQVHADDQDTGANGEVIYSIEKPP--GALSY 1087 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPPRSA-----TATXXXXXXXXXX 361 ID ++G V T DRE + YQ+ + DGG R A Sbjct: 1088 -FAIDDKTGIVTTLQSFDREEKPVYQIRIIGRDGGLGSSRGAERLMGVCQVDIRIGDKND 1146 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTR---GRFSITS 416 F QYE + ED G V+ ++ATDAD + +L Y I N R + T Sbjct: 1147 HDPVFQNKQYEATIKEDFEVGRSVLHVSATDADAGSNAKLTYSIQPQNDYFAIDRATGTV 1206 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPY 474 + L++ A+ + + R V A D+G R +V+I + D N PVF Y Sbjct: 1207 TSKMSLLSEAKS-EGQSSRVISFNVVANDNGNVSRKTVTLVRITVLDLGNDPPVFSQGVY 1265 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 +V ED IG++++ +SA+ N I YS+ N +++ +F I G + Sbjct: 1266 VVTVREDIAIGSSLIQLSASTKT---NKLIYYSIVP--GNVPSSNNPPRFQIRISKGIVW 1320 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 + LD + S + LT+ A P +S +++I + DVNDN P F Y ++ E+A Sbjct: 1321 NSHRLDHKETSNFSLTIRAETTD-PPMSAFANLKIFLEDVNDNPPEFVMPRYQGHVSENA 1379 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654 +G+SV QV A D D G NGR+ Y +D++ F +D +G++ T + DRE+ + Sbjct: 1380 PIGSSVLQVSARDRDSGENGRVTYSF-VQDKDSDKFGLDENTGLVTTREEFDREAQGRYT 1438 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 L A D G+P +++ IV I I D ND+PP+FE + E++ G + ++ A D Sbjct: 1439 LALKARDNGSPQKTTDTIVEIIITDENDNPPIFEEKVYNISVLESAASGMELLKVSAVDR 1498 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPL 774 D G NA V Y I G+ + +F + G+ + LD E+ Y+L + A Sbjct: 1499 DFGVNARVSYYISEGNINGAFEVNREFGT----IRLAGTLDRENV-DHYKLTLTAKDGKY 1553 Query: 775 WNDVRVEILVTDVNDNAP 792 + V + V D+NDN P Sbjct: 1554 SGEATVNVYVLDINDNNP 1571 Score = 280 bits (686), Expect = 5e-73 Identities = 216/733 (29%), Positives = 347/733 (47%), Gaps = 59/733 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + + ND++P F Y V E A S V T++ATD+D N V Y+I +T Sbjct: 926 VELTNVNDNAPRFSQSLYNVFVAEDAGSDQLVATVQATDKD---NDPVTYSIASGD-NTT 981 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARY-TVLVKATDQASPVSDR 129 N F I+ ++G + ++ E + Y T+ + A+D Sbjct: 982 N------------------FVINNKTGVIKLVSNRKPELIGPYYTMNISASDGLHV---- 1019 Query: 130 LSSTATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 S A + V I D N++ P F++ +Y V ED N + ++ A D D GAN + Sbjct: 1020 --SQAMVIVAIQDVNNHKPVFTDCASYHPVVMEDDP--PNTFVMQVHADDQDTGANGEVI 1075 Query: 189 YAIIGGNTQMQ-FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL--- 244 Y+I + F+ID +G V+ +++ D E+ Y++ I +DGG S +L+ Sbjct: 1076 YSIEKPPGALSYFAIDDKTGIVTTLQSFDREEKPVYQIRIIGRDGGLGSSRGAERLMGVC 1135 Query: 245 ---INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 I I D ND+ P F ++ ++ E+ +G S++ V A DAD G NA+LTY++ ++ Sbjct: 1136 QVDIRIGDKNDHDPVFQNKQYEATIKEDFEVGRSVLHVSATDADAGSNAKLTYSIQPQND 1195 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 +D + + + + ++ V A D G+ R Sbjct: 1196 YFAIDRATGTVTSKMSLLSEAKSEGQSSRVISFNVVANDNGNVSRKTVTLVRITVLDLGN 1255 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG-----RFSITS 416 F G Y V + ED G+ ++ L+A+ + ++Y I GN RF I Sbjct: 1256 DPPVFSQGVYVVTVREDIAIGSSLIQLSAS-TKTNKLIYYSIVPGNVPSSNNPPRFQI-- 1312 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSA-TDSGGRSDTAMVQINITDANNYAPVFENAPYT 475 + +G++ + LD K+ + LT+ A T S A ++I + D N+ P F Y Sbjct: 1313 RISKGIVWNSHRLDHKETSNFSLTIRAETTDPPMSAFANLKIFLEDVNDNPPEFVMPRYQ 1372 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 V E+APIG++VL VSA D D G N ++TYS + ++ +F ++ TG +TT Sbjct: 1373 GHVSENAPIGSSVLQVSARDRDSGENGRVTYSFVQDKDSD-------KFGLDENTGLVTT 1425 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 + DRE Y L + ARD G P + T VEI + D NDN P+F++++Y +++E A Sbjct: 1426 REEFDREAQGRYTLALKARDNGSPQKTTDTIVEIIITDENDNPPIFEEKVYNISVLESAA 1485 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655 G + +V A D D G+N R+ Y + + G+F ++ G IR LDRE+V + L Sbjct: 1486 SGMELLKVSAVDRDFGVNARVSYYIS-EGNINGAFEVNREFGTIRLAGTLDRENVDHYKL 1544 Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 A DG S V++ + DIND+ P FE +SEN P GT + ++RA DPD Sbjct: 1545 TLTAKDG---KYSGEATVNVYVLDINDNNPKFEKSHYRVNVSENRPAGTLVVKLRASDPD 1601 Query: 716 EGPNAVVHYSIKG 728 G + Y I G Sbjct: 1602 LGESGKFLYDISG 1614 Score = 274 bits (673), Expect = 2e-71 Identities = 260/892 (29%), Positives = 411/892 (46%), Gaps = 90/892 (10%) Query: 11 INVLDCNDHSPVFEM--QQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68 I V D ND++P F + + S+ + +GTTV + A DQD G +A V+Y +E AD Sbjct: 211 ITVTDINDNAPRFAIPREPLVTSIHQFRPAGTTVTKVTAYDQDSGSHALVKYGLE--NAD 268 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 + F I ++G + T A L + Y +V ATD P Sbjct: 269 SFP------------------FTITPQTGVIKTTAELRHFERDFYAFVVTATDSTPPFHK 310 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 T ++ + D NDN P F++ Y V V E++ VI + A D D GAN+ + Sbjct: 311 -----VTANIQLGDVNDNPPLFAQPVYKVFVRENLQ--GGHVIGQFAARDPDKGANARVT 363 Query: 189 YAIIG---GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 Y+II + FSI +G ++ + TLD E + + L I+A+D G P S Q++I Sbjct: 364 YSIINFEDSRSDNLFSIHPFTGVLTALSTLDREDLSRHILTIQAKDTGVPRMSGLAQIVI 423 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 + DVND+APRF + F + N P + + +A D D G N + Y++ GN Sbjct: 424 IVDDVNDHAPRFSSGSFHVEIPLNTPPDSRVFQARALDPDGGHNGLVRYSIIQ----GNK 479 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 +I+ G ++ +L T + VT D G P RS+TA Sbjct: 480 QGYFSINHIDGSLFLDEKL--TTLEPIDIKVT-RDMGQPERSSTA-DIRIFIHVQAGPPQ 535 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV 425 F+ + + E+EP G VV ++A D + Y I GN G F + G G +T Sbjct: 536 FLSSPFVGNVTENEPKGAFVVHISAASLDP---VMYSIVSGNEAGNFRL--HPGVGWLTT 590 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVF---ENAPYTASVFEDA 482 +PLD +++ RY + V A D R V +N+ + N+ P F N +V +D Sbjct: 591 VRPLDNEKQSRYKIIVMAMDLKNRVSKVEVIVNVLNVNDNKPKFVNIRNGIIEGNVLKDV 650 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 +G+ V+V+ A D+D + I LS I +E + F +N + G +T+ ++L R+ Sbjct: 651 AVGSRVMVIDAVDAD---RSDI---LSYRIEDEKARRY---FSVNNE-GVVTSTRVL-RD 699 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 S YL V+ D G P + + ++ +P QQ +I E A +GT V Sbjct: 700 LDSPYLFKVSVSDNGKPPMVAQAMARVVLLKY---QPQQDQQ--RTSIQESAALGTRVFT 754 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 + A N R + + P E F +DP SG +R LD E+V TH A A + Sbjct: 755 L--LTAKPIRNAR-YSIVSPL---ETKFRVDPYSGDVRVRSGLDYETVKTHRFTAEARNT 808 Query: 663 GTPPQ----SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 S V I + D+ND+PP F + E++P+GTT+ + A D D G Sbjct: 809 RDNTDYANIDSEADVKIVLRDLNDNPPEFFELSYRDTLPESAPVGTTVLSVTARDLDSGV 868 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPRKKYELVIRAASPPLWN- 776 N HY + +S FS++ G + T LD+E +P + +V + + P N Sbjct: 869 NGQFHYFV----ESQFFSVDPYTG----WITTKRPLDFETNPTHSFLVVAQDSGNPARNG 920 Query: 777 DVRVEILVTDVNDNAPVMKDFQIIFNNY--KDCFPVGPFGRVPAYDADVTDKLQYRILSG 834 RV + +T+VNDNAP + Q ++N + +D V A D D D + Y I SG Sbjct: 921 TARVIVELTNVNDNAP--RFSQSLYNVFVAEDAGSDQLVATVQATDKD-NDPVTYSIASG 977 Query: 835 NNANLILLNETTGSMTL-SPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVR 885 +N ++N TG + L S + + TM +S +DG++ +AM+ ++++ Sbjct: 978 DNTTNFVINNKTGVIKLVSNRKPELIGPYYTMNISASDGLHVSQAMVIVAIQ 1029 Score = 240 bits (587), Expect = 5e-61 Identities = 213/777 (27%), Positives = 347/777 (44%), Gaps = 85/777 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D NDH PVF+ +QYEA+++E G +VL + ATD D G NA++ Y+I+ Sbjct: 1139 IRIGDKNDHDPVFQNKQYEATIKEDFEVGRSVLHVSATDADAGSNAKLTYSIQ------- 1191 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASL--DREKVARYTVLVKATDQASPVSD 128 P++ D F ID +G + ++ SL + + + + ++ A+ + Sbjct: 1192 -PQN-------------DYFAIDRATGTVTSKMSLLSEAKSEGQSSRVISFNVVANDNGN 1237 Query: 129 RLSSTAT-IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 T T + + ++D ++ P FS+ Y V+V EDI++ + + A N I Sbjct: 1238 VSRKTVTLVRITVLDLGNDPPVFSQGVYVVTVREDIAIGSSLI-----QLSASTKTNKLI 1292 Query: 188 RYAIIGGNTQM-----QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 Y+I+ GN +F I G V LD+++ ++ L IRA+ P S Sbjct: 1293 YYSIVPGNVPSSNNPPRFQIRISKGIVWNSHRLDHKETSNFSLTIRAETT-DPPMSAFAN 1351 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT-DKDY 301 L I + DVNDN P F +Q VSEN PIG S+++V A D D G N +TY+ DKD Sbjct: 1352 LKIFLEDVNDNPPEFVMPRYQGHVSENAPIGSSVLQVSARDRDSGENGRVTYSFVQDKDS 1411 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 +D +G V T + DRE Q +Y L + A D G P ++ Sbjct: 1412 D-----KFGLDENTGLVTTREEFDREAQGRYTLALKARDNGSPQKTTDTIVEIIITDEND 1466 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419 F Y + + E G ++ ++A D D + R+ Y I+ GN G F + + G Sbjct: 1467 NPPIFEEKVYNISVLESAASGMELLKVSAVDRDFGVNARVSYYISEGNINGAFEVNREFG 1526 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479 I +A LD + Y LT++A D G S A V + + D N+ P FE + Y +V Sbjct: 1527 T--IRLAGTLDRENVDHYKLTLTAKD-GKYSGEATVNVYVLDINDNNPKFEKSHYRVNVS 1583 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSE--ISNEAVAHHDQQFVINPQTGAITTNK 537 E+ P GT V+ + A+D D+G + + Y +S + + V + +F P G + N Sbjct: 1584 ENRPAGTLVVKLRASDPDLGESGKFLYDISGQGLMIVGDVNDNKPRFPDEPYIGHVMENL 1643 Query: 538 LLDRETMSGYLLTVTARD-GGVPSLSDT--------------TDVEISVVDVNDNEPVFK 582 M+ + + D G ++DT + +I V + +P + Sbjct: 1644 KAGASVMTMSAVDIDDPDVGNNAVMTDTGVIRTRRMLDREKRSSYDIVVAATDGGDPPQE 1703 Query: 583 QQLYTANIMEDA----------LVGTSVSQ---VGATDA-------DVGLNGRIHYELDP 622 ++ I++DA + +S+ +G+T A D G+N ++ Y L+ Sbjct: 1704 GKVKVKVIVDDANDQHPQFTKRVFAAKISESAALGSTVATVSATDRDEGVNAKLKYSLEY 1763 Query: 623 KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDIN 681 + +EE F ID +G I LD E+ + LK D G P S T + +++ D N Sbjct: 1764 EAKEERPFRIDETTGEIILALTLDYETKRNYRLKVKVRDSGVPLSFSDTASLTVEVLDAN 1823 Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSL 737 D P FE + + E+ IG + + DPD + N G++ N F L Sbjct: 1824 DRAPRFEPLSYSAVVREDVDIGERLLRLEVTDPDSDSQNGGPFKFGISGNEKNLFEL 1880 Score = 237 bits (581), Expect = 2e-60 Identities = 206/760 (27%), Positives = 341/760 (44%), Gaps = 72/760 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD N++ P+F+ Y ++ EG+ GT +L + A D D G NA+V+Y Sbjct: 3 VRVLDGNNNDPIFQQSSYWVALPEGSPIGTELLRVTAEDLDSGSNADVKYQSS------- 55 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 D+F +D +G + + R K +Y+ V A DQ P Sbjct: 56 ----------------NDIFAVDETTGTITLQYQASRNK--KYSFTVTAFDQGKPSR--- 94 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SS AT++V+I +D+ P F + TY + E+ ++ I +++A GA +RY Sbjct: 95 SSVATVYVSIHSFSDSPPVFRKSTYEKRIPENFALKRG--IVRVEALANGGGAGGELRYY 152 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD----GGSPSRSNTTQLLIN 246 ++GG+ Q QF++D L+G++SL K LDYE+V SYRL IRA P +LI Sbjct: 153 LVGGDPQSQFNVDRLTGELSLKKPLDYEKVASYRLRIRAVQKTWRPNMPELPAEATVLIT 212 Query: 247 IRDVNDNAPRFY--TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + D+NDNAPRF S+ + P G ++ +V AYD D G +A + Y + + D Sbjct: 213 VTDINDNAPRFAIPREPLVTSIHQFRPAGTTVTKVTAYDQDSGSHALVKYGLENAD---- 268 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 P TI P++G + T+ +L + Y +VTATD P TA Sbjct: 269 -SFPFTITPQTGVIKTTAELRHFERDFYAFVVTATDSTPPFHKVTAN--IQLGDVNDNPP 325 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITG-GNTRGRFSITSQNGRG 421 F Y+V + E+ G + A D D+ + R+ Y I ++R + G Sbjct: 326 LFAQPVYKVFVRENLQGGHVIGQFAARDPDKGANARVTYSIINFEDSRSDNLFSIHPFTG 385 Query: 422 LITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVF 479 ++T LD + R++LT+ A D+G S A + I + D N++AP F + + + Sbjct: 386 VLTALSTLDREDLSRHILTIQAKDTGVPRMSGLAQIVIIVDDVNDHAPRFSSGSFHVEIP 445 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 + P + V A D D G N + YS+ + F IN G++ ++ L Sbjct: 446 LNTPPDSRVFQARALDPDGGHNGLVRYSIIQ-------GNKQGYFSINHIDGSLFLDEKL 498 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 T+ + VT RD G P S T D+ I + V P F + N+ E+ G Sbjct: 499 --TTLEPIDIKVT-RDMGQPERSSTADIRI-FIHVQAGPPQFLSSPFVGNVTENEPKGAF 554 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 V + A D + Y + E G+F + P G + T + LD E + + + +A Sbjct: 555 VVHISAASLD-----PVMYSI-VSGNEAGNFRLHPGVGWLTTVRPLDNEKQSRYKIIVMA 608 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVF---ESDCLTFYISENSPIGTTIGEIRAHDPDE 716 +D + S V V + + ++ND+ P F + + + ++ +G+ + I A D D Sbjct: 609 MD--LKNRVSKVEVIVNVLNVNDNKPKFVNIRNGIIEGNVLKDVAVGSRVMVIDAVDADR 666 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756 + ++ Y I+ FS+ ++ +D Y Sbjct: 667 --SDILSYRIEDEKARRYFSVNNEGVVTSTRVLRDLDSPY 704 Score = 233 bits (571), Expect = 4e-59 Identities = 212/710 (29%), Positives = 330/710 (46%), Gaps = 54/710 (7%) Query: 138 VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQ 197 V ++D N+N P F + +Y V++ E + + ++ A D D G+N+ ++Y ++ Sbjct: 3 VRVLDGNNNDPIFQQSSYWVALPEGSPI--GTELLRVTAEDLDSGSNADVKYQ----SSN 56 Query: 198 MQFSIDSLSGDVSLVKTLDYEQVRS--YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP 255 F++D +G + TL Y+ R+ Y + A D G PSRS+ + ++I +D+ P Sbjct: 57 DIFAVDETTGTI----TLQYQASRNKKYSFTVTAFDQGKPSRSSVATVYVSIHSFSDSPP 112 Query: 256 RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315 F S +++ + EN + IVRV+A G EL Y + G+ +D + Sbjct: 113 VFRKSTYEKRIPENFALKRGIVRVEALANGGGAGGELRYYLVG----GDPQSQFNVDRLT 168 Query: 316 GWVYTSGQLDRETQAKYQLLVTATD----GGDPPRSATATXXXXXXXXXXXXXXF-MPGQ 370 G + LD E A Y+L + A P A AT F +P + Sbjct: 169 GELSLKKPLDYEKVASYRLRIRAVQKTWRPNMPELPAEATVLITVTDINDNAPRFAIPRE 228 Query: 371 YEV-ELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQ 427 V + + P GT V +TA D D + + Y + ++ F+IT Q G + T A+ Sbjct: 229 PLVTSIHQFRPAGTTVTKVTAYDQDSGSHALVKYGLENADS-FPFTITPQTG-VIKTTAE 286 Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 F+++ Y V+ATDS I + D N+ P+F Y V E+ G Sbjct: 287 LRHFERD-FYAFVVTATDSTPPFHKVTANIQLGDVNDNPPLFAQPVYKVFVRENLQGGHV 345 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 + +A D D G NA++TYS I N + D F I+P TG +T LDRE +S + Sbjct: 346 IGQFAARDPDKGANARVTYS----IINFEDSRSDNLFSIHPFTGVLTALSTLDREDLSRH 401 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 +LT+ A+D GVP +S + I V DVND+ P F + I + + V Q A D Sbjct: 402 ILTIQAKDTGVPRMSGLAQIVIIVDDVNDHAPRFSSGSFHVEIPLNTPPDSRVFQARALD 461 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 D G NG + Y + + ++G F I+ G + ++ L ++ D+K V D G P + Sbjct: 462 PDGGHNGLVRYSI-IQGNKQGYFSINHIDGSLFLDEKL--TTLEPIDIK-VTRDMGQPER 517 Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 SST + I I + PP F S ++EN P G + I A D V YSI Sbjct: 518 SSTADIRIFIH-VQAGPPQFLSSPFVGNVTENEPKGAFVVHISAASLDP-----VMYSIV 571 Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDV-RVEILVT- 785 G+++ +F L G L T+ LD E + +Y++++ A L N V +VE++V Sbjct: 572 SGNEAGNFRLHPGVG----WLTTVRPLDNEK-QSRYKIIVMAMD--LKNRVSKVEVIVNV 624 Query: 786 -DVNDNAPVMKDFQ--IIFNNYKDCFPVGPFGRV-PAYDADVTDKLQYRI 831 +VNDN P + + II N VG V A DAD +D L YRI Sbjct: 625 LNVNDNKPKFVNIRNGIIEGNVLKDVAVGSRVMVIDAVDADRSDILSYRI 674 Score = 225 bits (550), Expect = 1e-56 Identities = 187/657 (28%), Positives = 285/657 (43%), Gaps = 50/657 (7%) Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 +++ + D N+N P F S + ++ E PIG ++RV A D D G NA++ Y ++ + Sbjct: 1 VIVRVLDGNNNDPIFQQSSYWVALPEGSPIGTELLRVTAEDLDSGSNADVKYQSSNDIFA 60 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 +D +G + Q R KY VTA D G P RS+ AT Sbjct: 61 --------VDETTGTITLQYQASRNK--KYSFTVTAFDQGKPSRSSVATVYVSIHSFSDS 110 Query: 363 XXXFMPGQYEVELAEDEP--PGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420 F YE + E+ G V A L Y + GG+ + +F++ G Sbjct: 111 PPVFRKSTYEKRIPENFALKRGIVRVEALANGGGAGGELRYYLVGGDPQSQFNVDRLTGE 170 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDT------AMVQINITDANNYAPVFE--NA 472 +++ +PLD+++ Y L + A R + A V I +TD N+ AP F Sbjct: 171 --LSLKKPLDYEKVASYRLRIRAVQKTWRPNMPELPAEATVLITVTDINDNAPRFAIPRE 228 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 P S+ + P GTTV V+A D D G +A + Y L + S F I PQTG Sbjct: 229 PLVTSIHQFRPAGTTVTKVTAYDQDSGSHALVKYGLENADSFP--------FTITPQTGV 280 Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592 I T L Y VTA D P T ++++ DVNDN P+F Q +Y + E Sbjct: 281 IKTTAELRHFERDFYAFVVTATDSTPPFHKVTANIQLG--DVNDNPPLFAQPVYKVFVRE 338 Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELD--PKDREEGSFVIDPASGVIRTNKALDRESV 650 + G + Q A D D G N R+ Y + R + F I P +GV+ LDRE + Sbjct: 339 NLQGGHVIGQFAARDPDKGANARVTYSIINFEDSRSDNLFSIHPFTGVLTALSTLDREDL 398 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710 + H L A D G P S + I ++D+ND P F S I N+P + + + R Sbjct: 399 SRHILTIQAKDTGVPRMSGLAQIVIIVDDVNDHAPRFSSGSFHVEIPLNTPPDSRVFQAR 458 Query: 711 AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS--DKAELVTMVDLDYESPRKKYELVIR 768 A DPD G N +V YSI G+ FS+ GS +L T+ +D + R + Sbjct: 459 ALDPDGGHNGLVRYSIIQGNKQGYFSINHIDGSLFLDEKLTTLEPIDIKVTRDMGQPERS 518 Query: 769 AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQ 828 + + D+R+ I V P + N + P G F V A D + Sbjct: 519 STA-----DIRIFI---HVQAGPPQFLSSPFV-GNVTENEPKGAF--VVHISAASLDPVM 567 Query: 829 YRILSGNNANLILLNETTGSMTLSPQLNTNVP---KLATMEVSVTDGVNEIKAMMQL 882 Y I+SGN A L+ G +T L+ K+ M + + + V++++ ++ + Sbjct: 568 YSIVSGNEAGNFRLHPGVGWLTTVRPLDNEKQSRYKIIVMAMDLKNRVSKVEVIVNV 624 Score = 121 bits (291), Expect = 3e-25 Identities = 86/274 (31%), Positives = 129/274 (47%), Gaps = 23/274 (8%) Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 Y + E+ G V+T++A D D+ + G N G+I + LD Sbjct: 1635 YIGHVMENLKAGASVMTMSAVDIDDPD------VGNNA-------VMTDTGVIRTRRMLD 1681 Query: 431 FKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTV 488 ++ Y + V+ATD G V++ + DAN+ P F + A + E A +G+TV Sbjct: 1682 REKRSSYDIVVAATDGGDPPQEGKVKVKVIVDDANDQHPQFTKRVFAAKISESAALGSTV 1741 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 VSATD D G+NA++ YSL E A ++ F I+ TG I LD ET Y Sbjct: 1742 ATVSATDRDEGVNAKLKYSLEYE------AKEERPFRIDETTGEIILALTLDYETKRNYR 1795 Query: 549 LTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 L V RD GVP S SDT + + V+D ND P F+ Y+A + ED +G + ++ TD Sbjct: 1796 LKVKVRDSGVPLSFSDTASLTVEVLDANDRAPRFEPLSYSAVVREDVDIGERLLRLEVTD 1855 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641 D ++ E+ F + GV++T Sbjct: 1856 PDSDSQNGGPFKFGISGNEKNLFEL-TEDGVLKT 1888 Score = 118 bits (285), Expect = 2e-24 Identities = 75/226 (33%), Positives = 118/226 (52%), Gaps = 22/226 (9%) Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630 V DVNDN+P F + Y ++ME+ G SV + A D D D + G+ Sbjct: 1620 VGDVNDNKPRFPDEPYIGHVMENLKAGASVMTMSAVDID--------------DPDVGNN 1665 Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690 + +GVIRT + LDRE +++D+ A DGG PPQ V V + ++D ND P F Sbjct: 1666 AVMTDTGVIRTRRMLDREKRSSYDIVVAATDGGDPPQEGKVKVKVIVDDANDQHPQFTKR 1725 Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK-GGDDSNSFSLETRQGSDKAELV 749 ISE++ +G+T+ + A D DEG NA + YS++ + F ++ G E++ Sbjct: 1726 VFAAKISESAALGSTVATVSATDRDEGVNAKLKYSLEYEAKEERPFRIDETTG----EII 1781 Query: 750 TMVDLDYESPRK-KYELVIRAASPPL-WND-VRVEILVTDVNDNAP 792 + LDYE+ R + ++ +R + PL ++D + + V D ND AP Sbjct: 1782 LALTLDYETKRNYRLKVKVRDSGVPLSFSDTASLTVEVLDANDRAP 1827 Score = 111 bits (266), Expect = 4e-22 Identities = 80/280 (28%), Positives = 131/280 (46%), Gaps = 26/280 (9%) Query: 142 DDNDNYPQFSEKTYTVSVDEDISVTDNPV-IAKIKATDADVGANSAIRYAIIGGNTQMQF 200 D NDN P+F ++ Y V E++ + + ++ + D DVG N+ + Sbjct: 1622 DVNDNKPRFPDEPYIGHVMENLKAGASVMTMSAVDIDDPDVGNNAVM------------- 1668 Query: 201 SIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260 + +G + + LD E+ SY +V+ A DGG P + ++ + + D ND P+F Sbjct: 1669 ---TDTGVIRTRRMLDREKRSSYDIVVAATDGGDPPQEGKVKVKVIVDDANDQHPQFTKR 1725 Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT 320 +F +SE+ +G ++ V A D DEGVNA+L Y++ +Y + P ID +G + Sbjct: 1726 VFAAKISESAALGSTVATVSATDRDEGVNAKLKYSL---EYEAKEERPFRIDETTGEIIL 1782 Query: 321 SGQLDRETQAKYQLLVTATDGGDP-PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE 379 + LD ET+ Y+L V D G P S TA+ F P Y + ED Sbjct: 1783 ALTLDYETKRNYRLKVKVRDSGVPLSFSDTASLTVEVLDANDRAPRFEPLSYSAVVREDV 1842 Query: 380 PPGTPVVTLTATDADEDNR----LHYEITGGNTRGRFSIT 415 G ++ L TD D D++ + I+ GN + F +T Sbjct: 1843 DIGERLLRLEVTDPDSDSQNGGPFKFGIS-GNEKNLFELT 1881 Score = 86.2 bits (204), Expect = 1e-14 Identities = 53/189 (28%), Positives = 92/189 (48%), Gaps = 20/189 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ V D ND P F + + A + E A+ G+TV T+ ATD+D G NA+++Y++E + Sbjct: 1709 KVIVDDANDQHPQFTKRVFAAKISESAALGSTVATVSATDRDEGVNAKLKYSLEYEAKE- 1767 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + FRID +G ++ +LD E Y + VK D P+S Sbjct: 1768 -----------------ERPFRIDETTGEIILALTLDYETKRNYRLKVKVRDSGVPLS-- 1808 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S TA++ V ++D ND P+F +Y+ V ED+ + + + ++ D+D ++ Sbjct: 1809 FSDTASLTVEVLDANDRAPRFEPLSYSAVVREDVDIGERLLRLEVTDPDSDSQNGGPFKF 1868 Query: 190 AIIGGNTQM 198 I G + Sbjct: 1869 GISGNEKNL 1877 >UniRef50_Q4SVN1 Cluster: Chromosome 1 SCAF13750, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1 SCAF13750, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 728 Score = 287 bits (703), Expect = 4e-75 Identities = 207/690 (30%), Positives = 327/690 (47%), Gaps = 34/690 (4%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F + ++G L+ +DRE++ TV K T + I V I D NDN P Sbjct: 48 FEANSKTGDLVVNERIDREELCPNTV--KCTLNLEAILSDPVVLHRIEVVISDLNDNAPV 105 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD- 208 F EK+Y++++ E S T + + A DAD G+NS Y + N+ FS+D SGD Sbjct: 106 FLEKSYSLNISE-WSPTGERFLLPL-AVDADTGSNSVTTYRL---NSNEYFSLDVQSGDD 160 Query: 209 ------VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLF 262 + L+++LD E+ +L + A DGG P ++ + + +N+ D NDN P F SL+ Sbjct: 161 QSASAELVLLRSLDREKQAVLKLTLTALDGGKPPKTGSLSIDVNVLDANDNTPTFSKSLY 220 Query: 263 QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322 + V+EN P G ++++ A D DEG N + Y+ + D+ ID SG V Sbjct: 221 KARVNENAPAGSPVIQLSATDLDEGDNGRVVYSFVKRGNFNPADV-FVIDAESGEVTVKA 279 Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382 LD ETQ+ +++ V A D G PRSA + + ED G Sbjct: 280 ALDYETQSAFEVHVQARDKGFSPRSANSKLLVEVVDVNDNAPEIAVTSLVNPVKEDAEIG 339 Query: 383 TPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440 + V +T TD D ++ + EI G+ + +N L+ V PLD ++ Y +T Sbjct: 340 SAVALVTVTDKDSGKNGKTRTEIV-GSVPFKLLSNYKNYYSLV-VDGPLDREKCSSYSIT 397 Query: 441 VSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498 ++A D G S T +V +++ D N+ AP F + V E++P+G + ++ATD D Sbjct: 398 ITAADEGSPPLSSTILVIVHVADVNDNAPAFSSPEVNIYVKENSPVGALIHTITATDPDK 457 Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558 NA +TYS+ + IN +TG I + + D E + + V A D GV Sbjct: 458 EENAIVTYSVMH--GSRITQQKTWLISINSETGDIVSLQSFDYEELKTFQFQVQATDSGV 515 Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618 P LS TT ++I + DVNDN P+FK+ + ++ E++ VG ++ + D D N ++ Y Sbjct: 516 PPLSSTTVIQIHISDVNDNAPLFKEPVVNVHVKENSPVGITILTITTADLDREENAKVTY 575 Query: 619 ELDP----KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674 L + I+ +G I ++ D E V T + A D G PP SS V V+ Sbjct: 576 SLIDGLFNSISVRSAVNINSDTGDITILQSFDYEEVKTFQFQVQATDSGVPPLSSNVSVN 635 Query: 675 IKIEDINDSPPVF------ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 + I D ND+ P + I ++ G + +IRA D D G NA++ Y + Sbjct: 636 VFILDENDNNPAILAPYSEHGSVNSESIPYSAEAGYFVAKIRAVDSDSGYNALLSYHLSE 695 Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYES 758 +N F + T G + + M D D +S Sbjct: 696 PKGNNLFRMGTSTGEIRTKR-RMSDNDLKS 724 Score = 276 bits (677), Expect = 6e-72 Identities = 200/676 (29%), Positives = 324/676 (47%), Gaps = 52/676 (7%) Query: 1 MSVPFCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVE 59 +S P +H+ ++ + D ND++PVF + Y ++ E + +G L A D D G N+ Sbjct: 83 LSDPVVLHRIEVVISDLNDNAPVFLEKSYSLNISEWSPTGERFLLPLAVDADTGSNSVTT 142 Query: 60 YTI---ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVL 116 Y + E + D + +D S L+ SLDREK A + Sbjct: 143 YRLNSNEYFSLDVQSGDD------------------QSASAELVLLRSLDREKQAVLKLT 184 Query: 117 VKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKA 176 + A D P + + +I VN++D NDN P FS+ Y V+E+ + +PVI ++ A Sbjct: 185 LTALDGGKPPK---TGSLSIDVNVLDANDNTPTFSKSLYKARVNEN-APAGSPVI-QLSA 239 Query: 177 TDADVGANSAIRYAII---GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233 TD D G N + Y+ + N F ID+ SG+V++ LDYE ++ + ++A+D G Sbjct: 240 TDLDEGDNGRVVYSFVKRGNFNPADVFVIDAESGEVTVKAALDYETQSAFEVHVQARDKG 299 Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293 RS ++LL+ + DVNDNAP + V E+ IG ++ V D D G N + Sbjct: 300 FSPRSANSKLLVEVVDVNDNAPEIAVTSLVNPVKEDAEIGSAVALVTVTDKDSGKNGK-- 357 Query: 294 YTMTDKDYTGNVDLPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352 T + G+V + + ++ + + G LDRE + Y + +TA D G PP S+T Sbjct: 358 ---TRTEIVGSVPFKLLSNYKNYYSLVVDGPLDREKCSSYSITITAADEGSPPLSSTILV 414 Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD-EDNRL-HYEITGGN--T 408 F + + + E+ P G + T+TATD D E+N + Y + G+ T Sbjct: 415 IVHVADVNDNAPAFSSPEVNIYVKENSPVGALIHTITATDPDKEENAIVTYSVMHGSRIT 474 Query: 409 RGRFSITSQNGR-GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNY 465 + + + S N G I Q D+++ + + V ATDSG S T ++QI+I+D N+ Sbjct: 475 QQKTWLISINSETGDIVSLQSFDYEELKTFQFQVQATDSGVPPLSSTTVIQIHISDVNDN 534 Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525 AP+F+ V E++P+G T+L ++ D D NA++TYSL + N Sbjct: 535 APLFKEPVVNVHVKENSPVGITILTITTADLDREENAKVTYSLIDGLFNSISVR--SAVN 592 Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF---- 581 IN TG IT + D E + + V A D GVP LS V + ++D NDN P Sbjct: 593 INSDTGDITILQSFDYEEVKTFQFQVQATDSGVPPLSSNVSVNVFILDENDNNPAILAPY 652 Query: 582 --KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639 + + +I A G V+++ A D+D G N + Y L + + F + ++G I Sbjct: 653 SEHGSVNSESIPYSAEAGYFVAKIRAVDSDSGYNALLSYHLS-EPKGNNLFRMGTSTGEI 711 Query: 640 RTNKALDRESVATHDL 655 RT + + + +H L Sbjct: 712 RTKRRMSDNDLKSHPL 727 Score = 266 bits (653), Expect = 5e-69 Identities = 199/693 (28%), Positives = 330/693 (47%), Gaps = 36/693 (5%) Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDGGS-PSRSNTTQLLINI 247 I+ G ++ F +S +GD+ + + +D E++ + + + + S P + +++I+ Sbjct: 39 IVSGYSKKYFEANSKTGDLVVNERIDREELCPNTVKCTLNLEAILSDPVVLHRIEVVIS- 97 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 D+NDNAP F + ++SE P G + A DAD G N+ TY + +Y ++D+ Sbjct: 98 -DLNDNAPVFLEKSYSLNISEWSPTGERFLLPLAVDADTGSNSVTTYRLNSNEYF-SLDV 155 Query: 308 PITIDPR-SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 D S + LDRE QA +L +TA DGG PP++ + + F Sbjct: 156 QSGDDQSASAELVLLRSLDREKQAVLKLTLTALDGGKPPKTGSLSIDVNVLDANDNTPTF 215 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADE-DN-RLHYE-ITGGNTRGRFSITSQNGRGLI 423 Y+ + E+ P G+PV+ L+ATD DE DN R+ Y + GN G + Sbjct: 216 SKSLYKARVNENAPAGSPVIQLSATDLDEGDNGRVVYSFVKRGNFNPADVFVIDAESGEV 275 Query: 424 TVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 TV LD++ + + + V A D G RS + + + + D N+ AP V ED Sbjct: 276 TVKAALDYETQSAFEVHVQARDKGFSPRSANSKLLVEVVDVNDNAPEIAVTSLVNPVKED 335 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 A IG+ V +V+ TD D G N + + + + ++++ + ++ + LDR Sbjct: 336 AEIGSAVALVTVTDKDSGKNGKTRTEIVGSVPFKLLSNYKNYY-------SLVVDGPLDR 388 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 E S Y +T+TA D G P LS T V + V DVNDN P F + E++ VG + Sbjct: 389 EKCSSYSITITAADEGSPPLSSTILVIVHVADVNDNAPAFSSPEVNIYVKENSPVGALIH 448 Query: 602 QVGATDADVGLNGRIHYELDPKDR--EEGSFVI--DPASGVIRTNKALDRESVATHDLKA 657 + ATD D N + Y + R ++ +++I + +G I + ++ D E + T + Sbjct: 449 TITATDPDKEENAIVTYSVMHGSRITQQKTWLISINSETGDIVSLQSFDYEELKTFQFQV 508 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A D G PP SST ++ I I D+ND+ P+F+ + ++ ENSP+G TI I D D Sbjct: 509 QATDSGVPPLSSTTVIQIHISDVNDNAPLFKEPVVNVHVKENSPVGITILTITTADLDRE 568 Query: 718 PNAVVHYS-IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PP 773 NA V YS I G +S S SD ++ + DYE K ++ ++A PP Sbjct: 569 ENAKVTYSLIDGLFNSISVRSAVNINSDTGDITILQSFDYEEV-KTFQFQVQATDSGVPP 627 Query: 774 LWNDVRVEILVTDVNDNAP-VMKDFQIIFNNYKDCFP----VGPF-GRVPAYDAD--VTD 825 L ++V V + + D NDN P ++ + + + P G F ++ A D+D Sbjct: 628 LSSNVSVNVFILDENDNNPAILAPYSEHGSVNSESIPYSAEAGYFVAKIRAVDSDSGYNA 687 Query: 826 KLQYRILSGNNANLILLNETTGSMTLSPQLNTN 858 L Y + NL + +TG + +++ N Sbjct: 688 LLSYHLSEPKGNNLFRMGTSTGEIRTKRRMSDN 720 Score = 226 bits (553), Expect = 6e-57 Identities = 162/546 (29%), Positives = 274/546 (50%), Gaps = 32/546 (5%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNG---- 419 F+ Y + ++E P G + A DAD + Y + N+ FS+ Q+G Sbjct: 106 FLEKSYSLNISEWSPTGERFLLPLAVDADTGSNSVTTYRL---NSNEYFSLDVQSGDDQS 162 Query: 420 -RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTA 476 + + + LD +++ LT++A D G ++ + + +N+ DAN+ P F + Y A Sbjct: 163 ASAELVLLRSLDREKQAVLKLTLTALDGGKPPKTGSLSIDVNVLDANDNTPTFSKSLYKA 222 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 V E+AP G+ V+ +SATD D G N ++ YS N A FVI+ ++G +T Sbjct: 223 RVNENAPAGSPVIQLSATDLDEGDNGRVVYSFVKR-GNFNPA---DVFVIDAESGEVTVK 278 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 LD ET S + + V ARD G S + + + VVDVNDN P + EDA + Sbjct: 279 AALDYETQSAFEVHVQARDKGFSPRSANSKLLVEVVDVNDNAPEIAVTSLVNPVKEDAEI 338 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 G++V+ V TD D G NG+ E+ + ++ + LDRE +++ + Sbjct: 339 GSAVALVTVTDKDSGKNGKTRTEIVGSVPFKLLSNYKNYYSLV-VDGPLDREKCSSYSIT 397 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 A D G+PP SST++V + + D+ND+ P F S + Y+ ENSP+G I I A DPD+ Sbjct: 398 ITAADEGSPPLSSTILVIVHVADVNDNAPAFSSPEVNIYVKENSPVGALIHTITATDPDK 457 Query: 717 GPNAVVHYSIKGGDD-SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---P 772 NA+V YS+ G + + S+ ++V++ DYE K ++ ++A P Sbjct: 458 EENAIVTYSVMHGSRITQQKTWLISINSETGDIVSLQSFDYEE-LKTFQFQVQATDSGVP 516 Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTD--KLQY 829 PL + ++I ++DVNDNAP+ K+ ++ + K+ PVG + D D + K+ Y Sbjct: 517 PLSSTTVIQIHISDVNDNAPLFKE-PVVNVHVKENSPVGITILTITTADLDREENAKVTY 575 Query: 830 RILSG--NNANL---ILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLS 883 ++ G N+ ++ + +N TG +T+ + K +V TD GV + + + ++ Sbjct: 576 SLIDGLFNSISVRSAVNINSDTGDITILQSFDYEEVKTFQFQVQATDSGVPPLSSNVSVN 635 Query: 884 VRLITE 889 V ++ E Sbjct: 636 VFILDE 641 Score = 120 bits (289), Expect = 6e-25 Identities = 96/328 (29%), Positives = 157/328 (47%), Gaps = 25/328 (7%) Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 SV E+ GT VV + +N + L + N + + F N +TG + N Sbjct: 7 SVSEEVDKGT---VVGNLAKHLNVNIR---DLHARNLNIVSGYSKKYFEANSKTGDLVVN 60 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTT---DVEISVVDVNDNEPVFKQQLYTANIMED 593 + +DRE + + T + LSD +E+ + D+NDN PVF ++ Y+ NI E Sbjct: 61 ERIDREELCPNTVKCTLNLEAI--LSDPVVLHRIEVVISDLNDNAPVFLEKSYSLNISEW 118 Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKD---REEGSFVIDPASGVIRTNKALDRESV 650 + G A DAD G N Y L+ + + S AS + ++LDRE Sbjct: 119 SPTGERFLLPLAVDADTGSNSVTTYRLNSNEYFSLDVQSGDDQSASAELVLLRSLDREKQ 178 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710 A L A+DGG PP++ ++ + + + D ND+ P F ++EN+P G+ + ++ Sbjct: 179 AVLKLTLTALDGGKPPKTGSLSIDVNVLDANDNTPTFSKSLYKARVNENAPAGSPVIQLS 238 Query: 711 AHDPDEGPNAVVHYS-IKGG--DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 A D DEG N V YS +K G + ++ F ++ G E+ LDYE+ + +E+ + Sbjct: 239 ATDLDEGDNGRVVYSFVKRGNFNPADVFVIDAESG----EVTVKAALDYET-QSAFEVHV 293 Query: 768 RAAS---PPLWNDVRVEILVTDVNDNAP 792 +A P + ++ + V DVNDNAP Sbjct: 294 QARDKGFSPRSANSKLLVEVVDVNDNAP 321 Score = 81.0 bits (191), Expect = 4e-13 Identities = 61/221 (27%), Positives = 104/221 (47%), Gaps = 21/221 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 QI++ D ND++P+F+ V+E + G T+LT+ D D +NA+V Y++ D Sbjct: 525 QIHISDVNDNAPLFKEPVVNVHVKENSPVGITILTITTADLDREENAKVTYSL----IDG 580 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L V+ I+ +G + S D E+V + V+ATD P Sbjct: 581 L----------FNSISVRSAVNINSDTGDITILQSFDYEEVKTFQFQVQATDSGVPP--- 627 Query: 130 LSSTATIHVNIIDDNDNYPQ----FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 LSS +++V I+D+NDN P +SE S S +AKI+A D+D G N+ Sbjct: 628 LSSNVSVNVFILDENDNNPAILAPYSEHGSVNSESIPYSAEAGYFVAKIRAVDSDSGYNA 687 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLV 226 + Y + F + + +G++ + + ++S+ LV Sbjct: 688 LLSYHLSEPKGNNLFRMGTSTGEIRTKRRMSDNDLKSHPLV 728 >UniRef50_Q19319 Cluster: Cadherin-4 precursor; n=1; Caenorhabditis elegans|Rep: Cadherin-4 precursor - Caenorhabditis elegans Length = 4307 Score = 285 bits (699), Expect = 1e-74 Identities = 317/1243 (25%), Positives = 537/1243 (43%), Gaps = 121/1243 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +++ D ND++P F ++ E A+ GT+V A D+D + + ++ LV Sbjct: 2679 VDIGDVNDNAPAFHGDYERFTISEDAAVGTSVTIFSAMDRDDSPSGRIRFS--LVEE--- 2733 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 NP F ++ SG L + LDREK+ Y ++ +ATD+ +D L Sbjct: 2734 NP----------------YFDLNENSGWLTVASQLDREKIDHYKLIARATDEGGFNTD-L 2776 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 T + D ND+ PQF ++ + + D+ + I D D+ N+ ++ Sbjct: 2777 PFTIVVS----DVNDSPPQFEKEEFNI----DLHLPSTSPILHFSIKDDDLSPNNVSQFF 2828 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I GN + F IDS + D+ L + E Y+L + A DG + +T++ IN++ Sbjct: 2829 IPKGNEEGVFWIDS-NNDLLLKRPEIVENKMQYQLKVTAFDGVFET---STKVKINLKSS 2884 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 D+ R + ++EN G ++ + + +T+ ++D D GNV Sbjct: 2885 KDSDIRCPEANKTVILAENSKKGTVVLGESSL-----LGPNVTFKLSDND--GNV---FV 2934 Query: 311 IDPRSGWVYT--SGQLDRETQAKYQL-LVTATDGGDPPRSA-TATXXXXXXXXXXXXXXF 366 ++ R+G V S Q+D E + + +T D + + T Sbjct: 2935 VNFRNGIVKVKESDQIDYEKNQQLEFHRLTIQDNSEVCKELITVVIENLNDNRPKIIEKL 2994 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 + + L E + + A DAD D + + + + G F I NG ++TV Sbjct: 2995 LKVSIDENLPTSEDARQYITRIVAEDADFDE-IKFRMVD-DFGGLFQIDDING--VVTVV 3050 Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 +PLD + + LTV A+D G D A + + + D N+ AP FE + Y+ V E IG Sbjct: 3051 KPLDSEILGFFNLTVVASD-GEFEDKATILVTVIDQNDNAPTFEKSTYSMKVMESESIGY 3109 Query: 487 TVLVVSATDSDVGINAQITYSLS-SEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETM 544 + A+ D N I Y L S++++ FV +N QTG +T K LD ET+ Sbjct: 3110 ELAHFRASGGDQ--NETIEYYLKPSDVTS---------FVNLNAQTGILTLAKPLDFETL 3158 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 S LTV A+D GVP L VEISV+D NDN P F+++ Y + E++ G V V Sbjct: 3159 SALKLTVVAKDSGVPPLETEAQVEISVMDENDNAPKFEKEKYVGKVKENSKSGEKVLTVK 3218 Query: 605 ATDADVGLNGRIHYELD-----PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 A D D G + YEL+ D F I+ ++G + ++++D E + ++LK +A Sbjct: 3219 ALDVDSEHFGAVSYELEIVSETTTDTPVLPFAIN-SNGDVLISQSIDYEKIKKYNLKVIA 3277 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 DGG PP S ++ I +ED ND P F+ +T + E IG + + D D GP Sbjct: 3278 KDGGRPPLRSEALLEIHVEDENDHAPTFDDCNMTALVQEGEAIGHRLLKFSVSDLD-GPK 3336 Query: 720 AVVHYSIK-GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDV 778 ++++ GD + SF + ++K EL+T L+Y K VI D Sbjct: 3337 NGAPFTVEIQGDGAKSFKV-----NEKLELLTAKKLEYRKKDKYLLTVIAKDVKGKTTDC 3391 Query: 779 RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK---LQYRILSGN 835 + I + + +AP MK +I N ++ P G GR+ A D D D+ L++ ++ G+ Sbjct: 3392 PLTIFIRQTSRHAPTMKPMKIQINTLQNELPEGIIGRLKASDEDEEDQNGLLRFGLVEGS 3451 Query: 836 -NANLILLNETTGSMTLSPQLNTN--------VPKLATMEVSVTDGVNEIKAMMQLSVRL 886 + + E+ + NT L T V+VTD + +++ V Sbjct: 3452 IQSPRAQVQESRSTHLFRVDPNTGDIWSDHSITQGLHTFNVTVTDSKFNTVSYVEVHVTS 3511 Query: 887 ITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKE-NIYIFSVQDDTDVTGN 945 I +++ +++++R+ M+ ++F+ + F ++ + + +I + SVQ Sbjct: 3512 IDNDVIDHAVSIRIRSMSVDEFMRKHVKEFRRIISHHLNLNDDSSIQLISVQAVPSTESE 3571 Query: 946 ILNVSFSARRPDAEV---GVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNIC 1002 S D E+ G + P H+ R+ + + +C Sbjct: 3572 --RRSRRNSMEDVEILMTAQRGLGRGYLKPDHIYSRLKNDFQNMNDQSQRMRYQLITEMC 3629 Query: 1003 VHEPCLNFEECLTVLKFGNASGF-VNSDSVLFRPIYPVTSFTCQCPEGFTGVNCE---TI 1058 CL EC V++ S V++D F + S C CP+GF G CE Sbjct: 3630 TTGVCLR-GECREVIELIEDSWTKVSTDDFSFVSPFHSRSAQCLCPDGFGGKRCEVETNQ 3688 Query: 1059 LTKASCEVDG--DGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCELRARSFPVSS-- 1114 K+ CE S+ S +CV G+ CS+ + C L V Sbjct: 3689 CAKSPCEQWQLCIPSVHNSTYECVCPL--GMEGDKCSVPSCQNDGKC-LEEAELSVGGDG 3745 Query: 1115 -FLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRGGGPGLR 1173 F + R+ L+++ T T +G+++++ + DF L LV+ G P Sbjct: 3746 YFEISLSNEIETRMELEIELKTTTHNGIIMWS---RGKRDFHMLRLVN------GTP--E 3794 Query: 1174 FSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCD 1216 + ++ G G +T + +V DG WH + I R M +DD D Sbjct: 3795 YHWNAGTGTGIVTSKTSVVDGQWHRIAISRRQRRTRMTVDDED 3837 Score = 238 bits (583), Expect = 1e-60 Identities = 248/916 (27%), Positives = 415/916 (45%), Gaps = 93/916 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEY--TIELVTAD 68 I +LD NDH+PVF + + G ++ + ATDQD G+N ++ Y T EL Sbjct: 480 IEILDSNDHAPVFSAKWMRQTPIVIGKPGDVLVKVDATDQDEGENGKIVYKFTSELPLEI 539 Query: 69 TLNPEDAXXXX--XXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 N + V+ ID G L+R S + Y K + P+ Sbjct: 540 NANTGEITLVEVPKKGNSWPATVWAID--LGLPLSRMS--ALNLMFYKNGTKIPAKPKPI 595 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 + S +N + P FS V V ED + V+AK++A D D G N Sbjct: 596 IIQES-----------ENKHSPVFSSFPEIVEVTEDAPI--GTVVAKLQANDEDTGYNGF 642 Query: 187 IRYAI--IGGNTQMQFSIDSLSGDVSL-----------VKTLDYE---------QVRSYR 224 IRY I I G++ ++D SG++++ ++ LD + + +++ Sbjct: 643 IRYVIHDIAGSSHEVLTVDEQSGEITVASDLSKLMKEKLEVLDVQVHYIKHVTSNISNFQ 702 Query: 225 LVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA 284 L + A D G+P +S+ + + I+DVN+++P+F + +SEN G I +V A D Sbjct: 703 LKVSAIDAGTPVKSSVKTMKLRIKDVNNHSPQFDEVSYYLRISENEKPGKDIFKVTANDF 762 Query: 285 DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP 344 D G N ++ +++ + +V I+ID ++G V LDRE Q + + A+D G P Sbjct: 763 DGGNNGKIKFSLGNNQEKSSV---ISIDAKTGIVKLLKSLDREDQDVHTFAIIASDEGFP 819 Query: 345 PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT 404 R + + + ED P G V + A D D + Sbjct: 820 MRVSVTNLTISVEDVNDNPPKCVVQHSRARIPEDLPHGAFVSCMAAFDEDIGQNSKLKFL 879 Query: 405 GGNTRGRFSITSQNGRGLITVAQ-PLDFKQERRYVLTVSATDSGG--RSDTAMVQINITD 461 + + F I +G I + PLD+ + + L++ D G S + + + + D Sbjct: 880 LNSEKVPFRIDHHSGCIFIHAPEYPLDYHKTPFFNLSIEVADHGDPILSTSCHLHVELVD 939 Query: 462 -ANNYAPV-FENAPYTASVFEDAPIGTTVLVVSA--TDSDVGINAQ-ITYSLSSEISNEA 516 A+N+ + F++ ASV+E++ IGT V+++ A T + + A+ + Y + I + Sbjct: 940 IAHNHLAIEFDDVAKEASVYENSEIGTEVIMIEAKETGDEQKVKAENLEYRI---IGGDG 996 Query: 517 VAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV-----PSLSDTTDVEISV 571 H F I+ Q G + T LLDRET S Y +TV ARD P D V I + Sbjct: 997 WPH----FSID-QKGTVRTTHLLDRETKSAYWITVEARDSKTDLYKDPRRRDVLHVFIRI 1051 Query: 572 VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN---GRIHYELDPKDREEG 628 +D ND+ PV K+ +Y A++ E++ + +V ATDAD N + ++++ D + Sbjct: 1052 LDRNDHRPVAKKPMYIASVAENSPANVVIVKVEATDADDVDNDAAAPLMFKIERGD-PQS 1110 Query: 629 SFVIDPASGVIRTN--KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686 F ID SG I T+ + LDRE + H+L DGG P S VIV + + D ND+ P Sbjct: 1111 FFRIDLTSGYITTSGIRRLDREKQSEHELWVSICDGGEPQLCSNVIVIVNVLDENDNSPT 1170 Query: 687 FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD-------DSNSFSLET 739 F + + Y S S + I A D DEG NA + Y+I GD + N + E Sbjct: 1171 F-TQAIHHY-SVRSKFAGKLCRIFAVDADEGENARLTYNITEGDARFSIDNNGNIIASEA 1228 Query: 740 RQGSDKAELVTMVDLDYESPRKKYEL--VIRAASPPLWNDVRVEILVTDVNDNAPVMKDF 797 G D++ +T+ D+ +P +++ V+ A+ + + +++ D+ Sbjct: 1229 IHG-DESYALTVQATDHGTPGQQFAATRVVLTANSAGQKPRKSKNSPPEISGK---KSDY 1284 Query: 798 QIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 I + D VG G++ A DAD D+L + I SG+ ++ + + TG + L+ ++ Sbjct: 1285 VIPIS---DADQVGLTVGKLEASDAD-GDELWWSISSGDPDSVFDVRQDTGQLLLAKKVE 1340 Query: 857 TNVPKLATMEVSVTDG 872 + +SVTDG Sbjct: 1341 LLKRGELRLNISVTDG 1356 Score = 229 bits (561), Expect = 6e-58 Identities = 227/809 (28%), Positives = 352/809 (43%), Gaps = 81/809 (10%) Query: 17 NDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI--------ELVTAD 68 N HSPVF V E A GT V L+A D+D G N + Y I E++T D Sbjct: 602 NKHSPVFSSFPEIVEVTEDAPIGTVVAKLQANDEDTGYNGFIRYVIHDIAGSSHEVLTVD 661 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 + E +++ + + + ++ + + V A D +PV Sbjct: 662 EQSGE--ITVASDLSKLMKEKLEVLDVQVHYIKHVT---SNISNFQLKVSAIDAGTPVK- 715 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 SS T+ + I D N++ PQF E +Y + + E+ + I K+ A D D G N I+ Sbjct: 716 --SSVKTMKLRIKDVNNHSPQFDEVSYYLRISENEKPGKD--IFKVTANDFDGGNNGKIK 771 Query: 189 YAIIGGNTQMQ---FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 +++ GN Q + SID+ +G V L+K+LD E + I A D G P R + T L I Sbjct: 772 FSL--GNNQEKSSVISIDAKTGIVKLLKSLDREDQDVHTFAIIASDEGFPMRVSVTNLTI 829 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 ++ DVNDN P+ + + E++P G + + A+D D G N++L + + + Sbjct: 830 SVEDVNDNPPKCVVQHSRARIPEDLPHGAFVSCMAAFDEDIGQNSKLKFLLNSE------ 883 Query: 306 DLPITIDPRSGWVYTSG---QLDRETQAKYQLLVTATDGGDPPRSATA--TXXXXXXXXX 360 +P ID SG ++ LD + L + D GDP S + Sbjct: 884 KVPFRIDHHSGCIFIHAPEYPLDYHKTPFFNLSIEVADHGDPILSTSCHLHVELVDIAHN 943 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR-----LHYEITGGNTRGRFSIT 415 F E + E+ GT V+ + A + ++ + L Y I GG+ FSI Sbjct: 944 HLAIEFDDVAKEASVYENSEIGTEVIMIEAKETGDEQKVKAENLEYRIIGGDGWPHFSI- 1002 Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDS-------GGRSDTAMVQINITDANNYAPV 468 + +G + LD + + Y +TV A DS R D V I I D N++ PV Sbjct: 1003 --DQKGTVRTTHLLDRETKSAYWITVEARDSKTDLYKDPRRRDVLHVFIRILDRNDHRPV 1060 Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528 + Y ASV E++P ++ V ATD+D ++ L +I F I+ Sbjct: 1061 AKKPMYIASVAENSPANVVIVKVEATDAD-DVDNDAAAPLMFKIER---GDPQSFFRIDL 1116 Query: 529 QTGAITTN--KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586 +G ITT+ + LDRE S + L V+ DGG P L V ++V+D NDN P F Q ++ Sbjct: 1117 TSGYITTSGIRRLDREKQSEHELWVSICDGGEPQLCSNVIVIVNVLDENDNSPTFTQAIH 1176 Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646 ++ G + ++ A DAD G N R+ Y + D F ID +I + Sbjct: 1177 HYSV-RSKFAG-KLCRIFAVDADEGENARLTYNITEGD---ARFSIDNNGNIIASEAIHG 1231 Query: 647 RESVATHDLKAVAIDGGTPPQ--SSTVIVHI------KIEDINDSPPVFESDCLTFY--I 696 ES A L A D GTP Q ++T +V K +SPP + I Sbjct: 1232 DESYA---LTVQATDHGTPGQQFAATRVVLTANSAGQKPRKSKNSPPEISGKKSDYVIPI 1288 Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756 S+ +G T+G++ A D D + +SI GD + F + RQ + + L V+L Sbjct: 1289 SDADQVGLTVGKLEASDAD---GDELWWSISSGDPDSVF--DVRQDTGQLLLAKKVEL-- 1341 Query: 757 ESPRKKYELVIRAASPPLWNDVRVEILVT 785 R + L I W+ V I V+ Sbjct: 1342 -LKRGELRLNISVTDGQAWDHSTVIIQVS 1369 Score = 214 bits (523), Expect = 3e-53 Identities = 200/792 (25%), Positives = 353/792 (44%), Gaps = 80/792 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 ++V+D ND P F + Y S+ E A G TV+ + ATD D +N +EY++ L Sbjct: 2472 LSVIDINDKPPFFVLPFYSTSISESAKEGDTVMMVSATDDD--ENDTIEYSL-------L 2522 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + ++ F + R G + L+ + ++ +KATD A+P Sbjct: 2523 DGSES------------QFFSVHPRQGTITVAKKLEHKAGVTLSLTIKATDSANPPH--- 2567 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +T T+ VNI ++ P+FS Y SV ED V + VI +++ + ++ IR+ Sbjct: 2568 HATTTVEVNIASESVKVPRFSNSHYLFSVMEDADVGN--VIGRVQQMETEI---DEIRFT 2622 Query: 191 IIGGNTQ----MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 I+ G+ + + FS++ +G + + +LD E+ +++ IRA G T + ++ Sbjct: 2623 IVPGSEESDSFLPFSVERSTGKIIVKSSLDRERKNQWKMTIRADAAGGVHA--ITTVTVD 2680 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 I DVNDNAP F+ + ++SE+ +G S+ A D D+ + + +++ +++ Sbjct: 2681 IGDVNDNAPAFHGDYERFTISEDAAVGTSVTIFSAMDRDDSPSGRIRFSLVEENPY---- 2736 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 ++ SGW+ + QLDRE Y+L+ ATD G + F Sbjct: 2737 --FDLNENSGWLTVASQLDREKIDHYKLIARATDEGG--FNTDLPFTIVVSDVNDSPPQF 2792 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLIT 424 ++ ++L P +P++ + D D +N + I GN G F I S N + Sbjct: 2793 EKEEFNIDL--HLPSTSPILHFSIKDDDLSPNNVSQFFIPKGNEEGVFWIDSNND---LL 2847 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 + +P + + +Y L V+A D G + V+IN+ + + A T + E++ Sbjct: 2848 LKRPEIVENKMQYQLKVTAFD-GVFETSTKVKINLKSSKDSDIRCPEANKTVILAENSKK 2906 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 GT VL S+ + +T+ LS N V + V ++ I K + + Sbjct: 2907 GTVVLGESSL-----LGPNVTFKLSDNDGNVFVVNFRNGIVKVKESDQIDYEK---NQQL 2958 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS----V 600 + LT+ L + + + ++NDN P ++L +I E+ + Sbjct: 2959 EFHRLTIQDNSEVCKEL-----ITVVIENLNDNRPKIIEKLLKVSIDENLPTSEDARQYI 3013 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 +++ A DAD I + + D G F ID +GV+ K LD E + +L VA Sbjct: 3014 TRIVAEDADF---DEIKFRM--VDDFGGLFQIDDINGVVTVVKPLDSEILGFFNLTVVAS 3068 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 DG +++ ++ I D ND+ P FE + + E+ IG + RA D+ N Sbjct: 3069 DGEFEDKATILVTVI---DQNDNAPTFEKSTYSMKVMESESIGYELAHFRASGGDQ--NE 3123 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRV 780 + Y +K D ++ +L + G L +D + S K + + PPL + +V Sbjct: 3124 TIEYYLKPSDVTSFVNLNAQTGI--LTLAKPLDFETLSALKLTVVAKDSGVPPLETEAQV 3181 Query: 781 EILVTDVNDNAP 792 EI V D NDNAP Sbjct: 3182 EISVMDENDNAP 3193 Score = 190 bits (464), Expect = 4e-46 Identities = 194/758 (25%), Positives = 317/758 (41%), Gaps = 75/758 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+V D ND+ P +Q A + E G V + A D+DIG+N+++++ L Sbjct: 829 ISVEDVNDNPPKCVVQHSRARIPEDLPHGAFVSCMAAFDEDIGQNSKLKFL--------L 880 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS---LDREKVARYTVLVKATDQASPVS 127 N E FRID SG + A LD K + + ++ D P+ Sbjct: 881 NSEKVP-------------FRIDHHSGCIFIHAPEYPLDYHKTPFFNLSIEVADHGDPI- 926 Query: 128 DRLSSTATIHVNIIDDNDNYP--QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 LS++ +HV ++D N+ +F + SV E+ + ++ + K T + + Sbjct: 927 --LSTSCHLHVELVDIAHNHLAIEFDDVAKEASVYENSEIGTEVIMIEAKETGDEQKVKA 984 Query: 186 A-IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS-----PSRSN 239 + Y IIGG+ FSID G V LD E +Y + + A+D + P R + Sbjct: 985 ENLEYRIIGGDGWPHFSIDQ-KGTVRTTHLLDRETKSAYWITVEARDSKTDLYKDPRRRD 1043 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 + I I D ND+ P ++ SV+EN P IV+V+A DAD+ V+ + + K Sbjct: 1044 VLHVFIRILDRNDHRPVAKKPMYIASVAENSPANVVIVKVEATDADD-VDNDAAAPLMFK 1102 Query: 300 DYTGNVDLPITIDPRSGWVYTSG--QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357 G+ ID SG++ TSG +LDRE Q++++L V+ DGG+P + Sbjct: 1103 IERGDPQSFFRIDLTSGYITTSGIRRLDREKQSEHELWVSICDGGEPQLCSNVIVIVNVL 1162 Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ 417 F + + + D E+ RL Y IT G+ R FSI + Sbjct: 1163 DENDNSPTFTQAIHHYSVRSKFAGKLCRIFAVDADEGENARLTYNITEGDAR--FSIDN- 1219 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAM-VQINITDANNYAPVFENAP- 473 NG + + A + Y LTV ATD G G+ A V + A +N+P Sbjct: 1220 NGNIIASEA----IHGDESYALTVQATDHGTPGQQFAATRVVLTANSAGQKPRKSKNSPP 1275 Query: 474 --------YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525 Y + + +G TV + A+D+D ++ +S+SS D F Sbjct: 1276 EISGKKSDYVIPISDADQVGLTVGKLEASDAD---GDELWWSISS-------GDPDSVFD 1325 Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585 + TG + K ++ L ++ DG D + V I V P F Sbjct: 1326 VRQDTGQLLLAKKVELLKRGELRLNISVTDG---QAWDHSTVIIQVSRQISQRPKFSASH 1382 Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD-REEGSFVIDPASGVIRTNKA 644 Y ++ E VGT + + A+ +G + D E ++P+SG + + Sbjct: 1383 YQTDVSERVAVGTQIYTLKASGESLGTKPLVFNLFSVDDVAMEDKIRVEPSSGNVIVMEP 1442 Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 LD E A ++AV + S + I D ND+ P F ++ E+ + Sbjct: 1443 LDYE--AARRIRAV-VQVQQANMKSFATFSVNINDENDNSPYFVGHTAFAFVDESDTVDD 1499 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 + + A D D G N +V YSI G++ + F ++ + G Sbjct: 1500 VLATVTAFDKDRGENGIVTYSIVSGNEESLFKIDAKSG 1537 Score = 188 bits (459), Expect = 1e-45 Identities = 199/801 (24%), Positives = 349/801 (43%), Gaps = 79/801 (9%) Query: 90 FRIDGRSGALLTRASLDR-EKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 F I ++G L A ++R E+V + V+ ++++L+ + + I+D ND+ P Sbjct: 436 FAIGSKNGILRVSAKINRSERVYNFKVIASLHG----INEKLAEK-DVSIEILDSNDHAP 490 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 FS K + + V+ K+ ATD D G N I Y +++ I++ +G+ Sbjct: 491 VFSAKWMRQT--PIVIGKPGDVLVKVDATDQDEGENGKIVYKF---TSELPLEINANTGE 545 Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSP-SRSNTTQLL--------------INIRD-VND 252 ++LV+ ++ S+ + A D G P SR + L+ I I++ N Sbjct: 546 ITLVEV--PKKGNSWPATVWAIDLGLPLSRMSALNLMFYKNGTKIPAKPKPIIIQESENK 603 Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312 ++P F + V+E+ PIG + ++QA D D G N + Y + D G+ +T+D Sbjct: 604 HSPVFSSFPEIVEVTEDAPIGTVVAKLQANDEDTGYNGFIRYVI--HDIAGSSHEVLTVD 661 Query: 313 PRSGWVYTSGQLDRETQAK--------------------YQLLVTATDGGDPPRSATATX 352 +SG + + L + + K +QL V+A D G P +S+ T Sbjct: 662 EQSGEITVASDLSKLMKEKLEVLDVQVHYIKHVTSNISNFQLKVSAIDAGTPVKSSVKTM 721 Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRF 412 F Y + ++E+E PG + +TA D D N + + GN + + Sbjct: 722 KLRIKDVNNHSPQFDEVSYYLRISENEKPGKDIFKVTANDFDGGNNGKIKFSLGNNQEKS 781 Query: 413 SITSQNGR-GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVF 469 S+ S + + G++ + + LD + + + + A+D G R + I++ D N+ P Sbjct: 782 SVISIDAKTGIVKLLKSLDREDQDVHTFAIIASDEGFPMRVSVTNLTISVEDVNDNPPKC 841 Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 A + ED P G V ++A D D+G N+++ + L+SE + HH I+ Sbjct: 842 VVQHSRARIPEDLPHGAFVSCMAAFDEDIGQNSKLKFLLNSEKVPFRIDHHSGCIFIH-- 899 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV--FKQQLYT 587 LD + L++ D G P LS + + + +VD+ N F Sbjct: 900 ----APEYPLDYHKTPFFNLSIEVADHGDPILSTSCHLHVELVDIAHNHLAIEFDDVAKE 955 Query: 588 ANIMEDALVGTSVSQVGAT---DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA 644 A++ E++ +GT V + A D + Y + D F ID G +RT Sbjct: 956 ASVYENSEIGTEVIMIEAKETGDEQKVKAENLEYRIIGGDGWP-HFSID-QKGTVRTTHL 1013 Query: 645 LDRESVATHDLKAVAIDGGT-----PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699 LDRE+ + + + A D T P + + V I+I D ND PV + ++EN Sbjct: 1014 LDRETKSAYWITVEARDSKTDLYKDPRRRDVLHVFIRILDRNDHRPVAKKPMYIASVAEN 1073 Query: 700 SPIGTTIGEIRAHDPDEGPN---AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756 SP I ++ A D D+ N A + + I+ GD + F ++ G + +D + Sbjct: 1074 SPANVVIVKVEATDADDVDNDAAAPLMFKIERGDPQSFFRIDLTSGYITTSGIRRLDREK 1133 Query: 757 ESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRV 816 +S + + + P L ++V V + V D NDN+P I + + F G R+ Sbjct: 1134 QSEHELWVSICDGGEPQLCSNVIVIVNVLDENDNSPTFTQ-AIHHYSVRSKF-AGKLCRI 1191 Query: 817 PAYDADVTD--KLQYRILSGN 835 A DAD + +L Y I G+ Sbjct: 1192 FAVDADEGENARLTYNITEGD 1212 Score = 184 bits (447), Expect = 4e-44 Identities = 218/905 (24%), Positives = 379/905 (41%), Gaps = 90/905 (9%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATD-QDIGKNAEVEYTIELV 65 +H I +LD NDH PV + Y ASV E + + ++ ++ATD D+ +A ++ Sbjct: 1045 LHVFIRILDRNDHRPVAKKPMYIASVAENSPANVVIVKVEATDADDVDNDAAAPLMFKIE 1104 Query: 66 TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRA--SLDREKVARYTVLVKATDQA 123 D Q FRID SG + T LDREK + + + V D Sbjct: 1105 RGDP-----------------QSFFRIDLTSGYITTSGIRRLDREKQSEHELWVSICDGG 1147 Query: 124 SPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183 P +L S + VN++D+NDN P F++ + SV + + +I A DAD G Sbjct: 1148 EP---QLCSNVIVIVNVLDENDNSPTFTQAIHHYSVRSKFAGK----LCRIFAVDADEGE 1200 Query: 184 NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS-NTTQ 242 N+ + Y I G+ + FSID+ +G++ + + ++ SY L ++A D G+P + T+ Sbjct: 1201 NARLTYNITEGDAR--FSIDN-NGNIIASEAIHGDE--SYALTVQATDHGTPGQQFAATR 1255 Query: 243 LLINIRDVND------NAPRFYT---SLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293 +++ N+P + S + +S+ +G ++ +++A DAD EL Sbjct: 1256 VVLTANSAGQKPRKSKNSPPEISGKKSDYVIPISDADQVGLTVGKLEASDAD---GDELW 1312 Query: 294 YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353 ++++ +G+ D + +G + + +++ + + +L ++ TDG S T Sbjct: 1313 WSIS----SGDPDSVFDVRQDTGQLLLAKKVELLKRGELRLNISVTDGQAWDHS---TVI 1365 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR-LHYEITG-GNTRGR 411 F Y+ +++E GT + TL A+ + L + + + Sbjct: 1366 IQVSRQISQRPKFSASHYQTDVSERVAVGTQIYTLKASGESLGTKPLVFNLFSVDDVAME 1425 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN 471 I + G + V +PLD++ RR V + +S A +NI D N+ +P F Sbjct: 1426 DKIRVEPSSGNVIVMEPLDYEAARRIRAVVQVQQANMKS-FATFSVNINDENDNSPYFVG 1484 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 A V E + + V+A D D G N +TYS+ S NE + F I+ ++G Sbjct: 1485 HTAFAFVDESDTVDDVLATVTAFDKDRGENGIVTYSIVS--GNE-----ESLFKIDAKSG 1537 Query: 532 AITTNKLLDRETMS-GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590 + K LD E +L + A D SL D + I + F +++Y + Sbjct: 1538 EVRLAKPLDPELQHVESILRIRAIDSAANSLKDEMSLHIRNSNEAPETAKFDRKVYQTTL 1597 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650 + GT V + A +G + Y+L+P F + SG + L + Sbjct: 1598 YDSTRPGTPVLVLNALH-----HGTVSYKLEPNCT---FFEVHTLSGAVHLATWLTKLK- 1648 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE-- 708 ++ AI T Q V KI N P+F I EN P G+++ Sbjct: 1649 HRKSVECTAIVESTEGQQDIAKVIAKIIRTNQHSPIFRRQVYRGTIRENMPTGSSVLSKS 1708 Query: 709 -----IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY 763 + A D D G N +V Y + D FS++ G+ + T + D+E K+Y Sbjct: 1709 LLPLVVSAIDEDPGSNGLVGYRMLSPKDEQMFSVDQYSGA----IRTQMSFDFEK-MKEY 1763 Query: 764 ELVIRA---ASPPLWNDVRVEILVT--DVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA 818 ++A PP + + I+VT D ND P + + G A Sbjct: 1764 SFYVQAFDMGQPPRRSLMPSLIVVTVIDENDEPPRFPSNSLDISMILPTANGVSVGGQTA 1823 Query: 819 YDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKA 878 D D L+Y + + + ++T + +++ KL +EV VTDG Sbjct: 1824 QDMDSVGSLRY-FIKDQSVPFSVDSKTGDVLVKDSNGISDMTKLFDLEVFVTDGKQSASY 1882 Query: 879 MMQLS 883 +M++S Sbjct: 1883 VMKIS 1887 Score = 182 bits (442), Expect = 2e-43 Identities = 193/812 (23%), Positives = 351/812 (43%), Gaps = 73/812 (8%) Query: 106 DREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSV-----D 160 D ++ ++ ATD + S S ++ I+D ++ S T +S+ Sbjct: 2311 DSAITGQFITIMSATDMDTTNSLDEESQKLLY-KIVDGDETLFNISPATGELSLARPVEQ 2369 Query: 161 EDISVTDNPVIAKIKATDADVGANSAI-RYAIIGGNTQMQFS------------------ 201 +D+ D + + TD + SA+ A+ GG +QFS Sbjct: 2370 DDLVNEDTKKVLNVSVTDGIIVNKSALLTVAVKGGVPPLQFSLAPTTSSNSSTSKEAWPV 2429 Query: 202 -IDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260 ID +G + + + L+Y + + Y++ + +D + R + L +++ D+ND P F Sbjct: 2430 AIDRKTGRIHVSRVLNYHRDKRYQIPLVVED--ATGRRAFSTLTLSVIDINDKPPFFVLP 2487 Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT 320 + S+SE+ G +++ V A D DE N + Y++ D G+ ++ PR G + Sbjct: 2488 FYSTSISESAKEGDTVMMVSATDDDE--NDTIEYSLLD----GSESQFFSVHPRQGTITV 2541 Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380 + +L+ + L + ATD +PP AT T F Y + ED Sbjct: 2542 AKKLEHKAGVTLSLTIKATDSANPPHHATTTVEVNIASESVKVPRFSNSHYLFSVMEDAD 2601 Query: 381 PGTPVVTLTATDADEDNRLHYEITGGNTRGRF-SITSQNGRGLITVAQPLDFKQERRYVL 439 G + + + + D + G F + + G I V LD +++ ++ + Sbjct: 2602 VGNVIGRVQQMETEIDEIRFTIVPGSEESDSFLPFSVERSTGKIIVKSSLDRERKNQWKM 2661 Query: 440 TVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499 T+ A +GG V ++I D N+ AP F ++ EDA +GT+V + SA D D Sbjct: 2662 TIRADAAGGVHAITTVTVDIGDVNDNAPAFHGDYERFTISEDAAVGTSVTIFSAMDRDDS 2721 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 + +I +SL E + F +N +G +T LDRE + Y L A D G Sbjct: 2722 PSGRIRFSLVEE---------NPYFDLNENSGWLTVASQLDREKIDHYKLIARATDEG-- 2770 Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS-VSQVGATDADVGLNGRIHY 618 + I V DVND+ P F+++ + ++ L TS + D D+ N + Sbjct: 2771 GFNTDLPFTIVVSDVNDSPPQFEKEEFNIDL---HLPSTSPILHFSIKDDDLSPNNVSQF 2827 Query: 619 ELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678 + PK EEG F ID + ++ + E+ + LK A DG ++ST V I ++ Sbjct: 2828 FI-PKGNEEGVFWIDSNNDLLLKRPEI-VENKMQYQLKVTAFDGVF--ETSTK-VKINLK 2882 Query: 679 DINDSPPVFESDCLTFYISENSPIGTTI-GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL 737 DS T ++ENS GT + GE GPN S +D N F + Sbjct: 2883 SSKDSDIRCPEANKTVILAENSKKGTVVLGESSL----LGPNVTFKLS---DNDGNVFVV 2935 Query: 738 ETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDF 797 R G K + +D + + + L I+ S + ++ + +++ ++NDN P + + Sbjct: 2936 NFRNGIVKVKESDQIDYEKNQQLEFHRLTIQDNS-EVCKEL-ITVVIENLNDNRPKIIE- 2992 Query: 798 QIIFNNYKDCFPVGP-----FGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLS 852 +++ + + P R+ A DAD D++++R++ + L +++ G +T+ Sbjct: 2993 KLLKVSIDENLPTSEDARQYITRIVAEDADF-DEIKFRMVD-DFGGLFQIDDINGVVTVV 3050 Query: 853 PQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884 L++ + + V +DG E KA + ++V Sbjct: 3051 KPLDSEILGFFNLTVVASDGEFEDKATILVTV 3082 Score = 175 bits (427), Expect = 1e-41 Identities = 220/912 (24%), Positives = 391/912 (42%), Gaps = 92/912 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ + D N+HSP F+ Y + E G + + A D D G N ++++++ Sbjct: 722 KLRIKDVNNHSPQFDEVSYYLRISENEKPGKDIFKVTANDFDGGNNGKIKFSLG------ 775 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N ++ V ID ++G + SLDRE +T + A+D+ P+ R Sbjct: 776 -NNQEK-----------SSVISIDAKTGIVKLLKSLDREDQDVHTFAIIASDEGFPM--R 821 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 +S T + +++ D NDN P+ + + ED+ ++ + A D D+G NS +++ Sbjct: 822 VSVT-NLTISVEDVNDNPPKCVVQHSRARIPEDL--PHGAFVSCMAAFDEDIGQNSKLKF 878 Query: 190 AIIGGNTQMQFSIDSLSGDVSL---VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 + + ++ F ID SG + + LDY + + L I D G P S + L + Sbjct: 879 LL--NSEKVPFRIDHHSGCIFIHAPEYPLDYHKTPFFNLSIEVADHGDPILSTSCHLHVE 936 Query: 247 IRDVNDN--APRFYTSLFQESVSENVPIGYSIVRVQAYDA--DEGVNAE-LTYTMTDKDY 301 + D+ N A F + SV EN IG ++ ++A + ++ V AE L Y + D Sbjct: 937 LVDIAHNHLAIEFDDVAKEASVYENSEIGTEVIMIEAKETGDEQKVKAENLEYRIIGGDG 996 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG-----GDPPRSATATXXXXX 356 + +ID + G V T+ LDRET++ Y + V A D DP R Sbjct: 997 WPH----FSID-QKGTVRTTHLLDRETKSAYWITVEARDSKTDLYKDPRRRDVLHVFIRI 1051 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DN----RLHYEITGGNTRGR 411 Y +AE+ P +V + ATDAD+ DN L ++I G+ + Sbjct: 1052 LDRNDHRPVAKKPMYIASVAENSPANVVIVKVEATDADDVDNDAAAPLMFKIERGDPQSF 1111 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVF 469 F I +G + + LD +++ + L VS D G +V +N+ D N+ +P F Sbjct: 1112 FRIDLTSGYITTSGIRRLDREKQSEHELWVSICDGGEPQLCSNVIVIVNVLDENDNSPTF 1171 Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 A + SV + + + A D+D G NA++TY+ + D +F I+ Sbjct: 1172 TQAIHHYSV--RSKFAGKLCRIFAVDADEGENARLTYN---------ITEGDARFSIDNN 1220 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLS-DTTDVEISVVDV------NDNEP--- 579 I + + E+ Y LTV A D G P T V ++ + N P Sbjct: 1221 GNIIASEAIHGDES---YALTVQATDHGTPGQQFAATRVVLTANSAGQKPRKSKNSPPEI 1277 Query: 580 VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639 K+ Y I + VG +V ++ A+DAD + + + D + F + +G + Sbjct: 1278 SGKKSDYVIPISDADQVGLTVGKLEASDAD---GDELWWSISSGD-PDSVFDVRQDTGQL 1333 Query: 640 RTNKALDRESVATHDLKA-VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698 K + E + +L+ +++ G STVI+ + I+ P F + +SE Sbjct: 1334 LLAKKV--ELLKRGELRLNISVTDGQAWDHSTVIIQVS-RQISQRPK-FSASHYQTDVSE 1389 Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758 +GT I ++A G +V +++ DD + + R ++ M LDYE+ Sbjct: 1390 RVAVGTQIYTLKASGESLGTKPLV-FNLFSVDDV-AMEDKIRVEPSSGNVIVMEPLDYEA 1447 Query: 759 PRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP-VMKDFQIIFNNYKDCFPVGPFGRVP 817 R + V++ + + + + D NDN+P + F + D V Sbjct: 1448 AR-RIRAVVQVQQANMKSFATFSVNINDENDNSPYFVGHTAFAFVDESDTVD-DVLATVT 1505 Query: 818 AYDADVTDK--LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKL-ATMEVSVTD-GV 873 A+D D + + Y I+SGN +L ++ +G + L+ L+ + + + + + D Sbjct: 1506 AFDKDRGENGIVTYSIVSGNEESLFKIDAKSGEVRLAKPLDPELQHVESILRIRAIDSAA 1565 Query: 874 NEIKAMMQLSVR 885 N +K M L +R Sbjct: 1566 NSLKDEMSLHIR 1577 Score = 159 bits (386), Expect = 1e-36 Identities = 188/809 (23%), Positives = 335/809 (41%), Gaps = 62/809 (7%) Query: 92 IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151 ID ++G + L+ + RY + + D R ST T+ ++ID ND P F Sbjct: 2431 IDRKTGRIHVSRVLNYHRDKRYQIPLVVEDATGR---RAFSTLTL--SVIDINDKPPFFV 2485 Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSL 211 Y+ S+ E S + + + ATD D N I Y+++ G+ FS+ G +++ Sbjct: 2486 LPFYSTSISE--SAKEGDTVMMVSATDDD--ENDTIEYSLLDGSESQFFSVHPRQGTITV 2541 Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271 K L+++ + L I+A D +P TT + +NI + PRF S + SV E+ Sbjct: 2542 AKKLEHKAGVTLSLTIKATDSANPPHHATTTVEVNIASESVKVPRFSNSHYLFSVMEDAD 2601 Query: 272 IGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK 331 +G I RVQ + + E+ +T+ + LP +++ +G + LDRE + + Sbjct: 2602 VGNVIGRVQQMETEID---EIRFTIVPGSEESDSFLPFSVERSTGKIIVKSSLDRERKNQ 2658 Query: 332 YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE-VELAEDEPPGTPVVTLTA 390 +++ + A G T T G YE ++ED GT V +A Sbjct: 2659 WKMTIRADAAGGVHAITTVTVDIGDVNDNAPA---FHGDYERFTISEDAAVGTSVTIFSA 2715 Query: 391 TDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG 448 D D+ R+ + + N F + + G +TVA LD ++ Y L ATD GG Sbjct: 2716 MDRDDSPSGRIRFSLVEENP--YFDLNENS--GWLTVASQLDREKIDHYKLIARATDEGG 2771 Query: 449 RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508 + I ++D N+ P FE + + P + +L S D D+ N ++ Sbjct: 2772 FNTDLPFTIVVSDVNDSPPQFEKEEFNIDL--HLPSTSPILHFSIKDDDLSPN-NVSQFF 2828 Query: 509 SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568 + + E V D + + I NK+ Y L VTA DG +T V+ Sbjct: 2829 IPKGNEEGVFWIDSNNDLLLKRPEIVENKM-------QYQLKVTAFDG---VFETSTKVK 2878 Query: 569 ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG 628 I++ D++ + T + E++ GT V +G + L + ++L D + Sbjct: 2879 INLKSSKDSDIRCPEANKTVILAENSKKGTVV--LGESSL---LGPNVTFKL--SDNDGN 2931 Query: 629 SFVIDPASGVIRTNKA--LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686 FV++ +G+++ ++ +D E + + I + + ++ + IE++ND+ P Sbjct: 2932 VFVVNFRNGIVKVKESDQIDYEKNQQLEFHRLTIQDNS--EVCKELITVVIENLNDNRPK 2989 Query: 687 FESDCLTFYISENSPIGTT----IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 L I EN P I I A D D + + + D F ++ G Sbjct: 2990 IIEKLLKVSIDENLPTSEDARQYITRIVAEDADFDE---IKFRMV-DDFGGLFQIDDING 3045 Query: 743 SDKAELVTMV-DLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801 +VT+V LD E + L + A+ + + + V D NDNAP + Sbjct: 3046 -----VVTVVKPLDSEI-LGFFNLTVVASDGEFEDKATILVTVIDQNDNAPTFEKSTYSM 3099 Query: 802 NNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPK 861 + A D + ++Y + + + + LN TG +TL+ L+ Sbjct: 3100 KVMESESIGYELAHFRASGGDQNETIEYYLKPSDVTSFVNLNAQTGILTLAKPLDFETLS 3159 Query: 862 LATMEVSVTD-GVNEIKAMMQLSVRLITE 889 + V D GV ++ Q+ + ++ E Sbjct: 3160 ALKLTVVAKDSGVPPLETEAQVEISVMDE 3188 Score = 152 bits (368), Expect = 2e-34 Identities = 203/770 (26%), Positives = 326/770 (42%), Gaps = 86/770 (11%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLT-------LKATDQDIGKNAEVEYTIELV 65 ++ N HSP+F Q Y ++RE +G++VL+ + A D+D G N V Y + Sbjct: 1675 IIRTNQHSPIFRRQVYRGTIRENMPTGSSVLSKSLLPLVVSAIDEDPGSNGLVGYRM--- 1731 Query: 66 TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125 L+P+D + +F +D SGA+ T+ S D EK+ Y+ V+A D P Sbjct: 1732 ----LSPKD------------EQMFSVDQYSGAIRTQMSFDFEKMKEYSFYVQAFDMGQP 1775 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 L + + V +ID+ND P+F + +S+ I T N V T D+ + Sbjct: 1776 PRRSLMPSLIV-VTVIDENDEPPRFPSNSLDISM---ILPTANGVSVG-GQTAQDMDSVG 1830 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLD--YEQVRSYRLVIRAQDGGSPSRSNTTQL 243 ++RY I + + FS+DS +GDV LVK + + + + L + DG +S + + Sbjct: 1831 SLRYFI--KDQSVPFSVDSKTGDV-LVKDSNGISDMTKLFDLEVFVTDG---KQSASYVM 1884 Query: 244 LINIRDVNDNAPRFYTSLFQESVSEN--VPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 I+ ++ +F + + S+ EN +P G SI+ A D+ D Sbjct: 1885 KISTISTENSKFKFTRNEYHTSLIENTTLPPG-SIILSVATIGDK----------LDHFS 1933 Query: 302 TGNVDLPITIDPRSGWVYTSG-QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 N I P +G + +SG LDRE A +L+V A P A A Sbjct: 1934 IVNPHEAFFIHPGTGVISSSGIALDREKSAIIRLVVQAKSHEKNPVMARALVVVGIENIN 1993 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420 FM Y++ + + GT V+ D DE + + I+ N F I G+ Sbjct: 1994 DETPIFMGTPYDITIGHSD-IGTVVLEPKVIDNDEGDVV--TISSENMPEYFKIV--GGK 2048 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGG-RSDTAMVQINITDANNYAPVFENAPYTASVF 479 ++ P +++ + + A D+G V+I + D PVF YTA + Sbjct: 2049 VVLGKKLPSIEEEDLEFNFKLIAKDNGSVHRVEEPVKIRVVD--KARPVFSQNVYTAVIS 2106 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 +++ +TVLV S + S S + + F ++ TG + N L Sbjct: 2107 KESTKKSTVLVKVMAKSSL-------QSKSKGLIGYRILDKKSPFSVDFLTGEVRLNN-L 2158 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD-VNDNEPVFKQQLYTANIMEDALVGT 598 + Y V AR+ P + VEI V + + PVF++ YTA+ E +G Sbjct: 2159 KMLAETNYTFEVEAREVTRPKMIAKAQVEIIVKSGITTHAPVFEKLKYTASTPESTSIGQ 2218 Query: 599 SVSQVGATDADVGLNGRIHYELD-PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 + + AT +D N I Y L KD E I P +G + LD E +DLK Sbjct: 2219 RLLTIKATTSDE--NDTIEYSLSGSKDIE-----IHPETGDVTITGQLDYEKTQKYDLKL 2271 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-- 715 VA G S + + IED+ND P F ++ IS+++ G I + A D D Sbjct: 2272 VATSSGKQVSSEAEFI-VLIEDVNDEMPEFIRSDVSAKISDSAITGQFITIMSATDMDTT 2330 Query: 716 ---EGPNAVVHYSIKGGDDSNSFSLETRQGS-DKAELVTMVDLDYESPRK 761 + + + Y I GD++ F++ G A V DL E +K Sbjct: 2331 NSLDEESQKLLYKIVDGDET-LFNISPATGELSLARPVEQDDLVNEDTKK 2379 Score = 143 bits (347), Expect = 5e-32 Identities = 191/785 (24%), Positives = 333/785 (42%), Gaps = 84/785 (10%) Query: 134 ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK------IKATDADVGANSAI 187 A + II N + P F + Y ++ E++ T + V++K + A D D G+N + Sbjct: 1669 AKVIAKIIRTNQHSPIFRRQVYRGTIRENMP-TGSSVLSKSLLPLVVSAIDEDPGSNGLV 1727 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN--TTQLLI 245 Y ++ + FS+D SG + + D+E+++ Y ++A D G P R + + +++ Sbjct: 1728 GYRMLSPKDEQMFSVDQYSGAIRTQMSFDFEKMKEYSFYVQAFDMGQPPRRSLMPSLIVV 1787 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 + D ND PRF ++ S+ G S+ A D D L Y + D+ Sbjct: 1788 TVIDENDEPPRFPSNSLDISMILPTANGVSVGGQTAQDMDS--VGSLRYFIKDQ------ 1839 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 +P ++D ++G V K + L V TDG +SA+ Sbjct: 1840 SVPFSVDSKTGDVLVKDSNGISDMTKLFDLEVFVTDG---KQSASYVMKISTISTENSKF 1896 Query: 365 XFMPGQYEVELAEDE--PPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422 F +Y L E+ PPG+ ++ AT D+ + H+ I N F I G G+ Sbjct: 1897 KFTRNEYHTSLIENTTLPPGS-IILSVATIGDKLD--HFSIV--NPHEAFFI--HPGTGV 1949 Query: 423 ITVAQ-PLDFKQER--RYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479 I+ + LD ++ R V+ + + A+V + I + N+ P+F PY ++ Sbjct: 1950 ISSSGIALDREKSAIIRLVVQAKSHEKNPVMARALVVVGIENINDETPIFMGTPYDITI- 2008 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 + IGT VL D+D G ++SSE E + V+ + +I Sbjct: 2009 GHSDIGTVVLEPKVIDNDEG----DVVTISSENMPEYFKIVGGKVVLGKKLPSI------ 2058 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 + E + + +G V + + V+I VVD PVF Q +YTA I +++ ++ Sbjct: 2059 EEEDLEFNFKLIAKDNGSVHRVEE--PVKIRVVD--KARPVFSQNVYTAVISKESTKKST 2114 Query: 600 --VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 V + + G I Y + K + F +D +G +R N L + + + Sbjct: 2115 VLVKVMAKSSLQSKSKGLIGYRILDK---KSPFSVDFLTGEVRLNN-LKMLAETNYTFEV 2170 Query: 658 VAIDGGTPPQSSTVIVHIKIED-INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 A + P + V I ++ I PVFE T E++ IG + I+A DE Sbjct: 2171 EAREVTRPKMIAKAQVEIIVKSGITTHAPVFEKLKYTASTPESTSIGQRLLTIKATTSDE 2230 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIRAASPPLW 775 N + YS+ G D +E + ++ LDYE +K +LV ++ + Sbjct: 2231 --NDTIEYSLSGSKD-----IEIH--PETGDVTITGQLDYEKTQKYDLKLVATSSGKQVS 2281 Query: 776 NDVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFPVGPFGRV-PAYDADVTD------- 825 ++ +L+ DVND P + D + D G F + A D D T+ Sbjct: 2282 SEAEFIVLIEDVNDEMPEFIRSD---VSAKISDSAITGQFITIMSATDMDTTNSLDEESQ 2338 Query: 826 KLQYRILSGNNANLILLNETTGSMTLSPQLN----TNVPKLATMEVSVTDGVNEIK-AMM 880 KL Y+I+ G+ L ++ TG ++L+ + N + VSVTDG+ K A++ Sbjct: 2339 KLLYKIVDGDE-TLFNISPATGELSLARPVEQDDLVNEDTKKVLNVSVTDGIIVNKSALL 2397 Query: 881 QLSVR 885 ++V+ Sbjct: 2398 TVAVK 2402 Score = 111 bits (266), Expect = 4e-22 Identities = 133/533 (24%), Positives = 224/533 (42%), Gaps = 51/533 (9%) Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVF 469 F+I S+NG ++ V+ ++ + ER Y V A+ G A V I I D+N++APVF Sbjct: 436 FAIGSKNG--ILRVSAKIN-RSERVYNFKVIASLHGINEKLAEKDVSIEILDSNDHAPVF 492 Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN-P 528 + G ++ V ATD D G N +I Y +SE+ E A+ + ++ P Sbjct: 493 SAKWMRQTPIVIGKPGDVLVKVDATDQDEGENGKIVYKFTSELPLEINANTGEITLVEVP 552 Query: 529 QTG--------AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580 + G AI L R MS L +P+ ++ S N + PV Sbjct: 553 KKGNSWPATVWAIDLGLPLSR--MSALNLMFYKNGTKIPAKPKPIIIQESE---NKHSPV 607 Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFVIDPASGVI 639 F + EDA +GT V+++ A D D G NG I Y + D +D SG I Sbjct: 608 FSSFPEIVEVTEDAPIGTVVAKLQANDEDTGYNGFIRYVIHDIAGSSHEVLTVDEQSGEI 667 Query: 640 RTNKALDR--------------------ESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679 L + +++ LK AID GTP +SS + ++I+D Sbjct: 668 TVASDLSKLMKEKLEVLDVQVHYIKHVTSNISNFQLKVSAIDAGTPVKSSVKTMKLRIKD 727 Query: 680 INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS-FSLE 738 +N+ P F+ ISEN G I ++ A+D D G N + +S+ + +S S++ Sbjct: 728 VNNHSPQFDEVSYYLRISENEKPGKDIFKVTANDFDGGNNGKIKFSLGNNQEKSSVISID 787 Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQ 798 + G K L+ +D + + + P + + I V DVNDN P Q Sbjct: 788 AKTGIVK--LLKSLDREDQDVHTFAIIASDEGFPMRVSVTNLTISVEDVNDNPPKCV-VQ 844 Query: 799 IIFNNYKDCFPVGPF-GRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTL-SPQ-- 854 + P G F + A+D D+ + + L + ++ +G + + +P+ Sbjct: 845 HSRARIPEDLPHGAFVSCMAAFDEDIGQNSKLKFLLNSEKVPFRIDHHSGCIFIHAPEYP 904 Query: 855 LNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAE 906 L+ + + + V D G + L V L+ ++ N + + +D+ E Sbjct: 905 LDYHKTPFFNLSIEVADHGDPILSTSCHLHVELV--DIAHNHLAIEFDDVAKE 955 Score = 93.1 bits (221), Expect = 1e-16 Identities = 80/278 (28%), Positives = 130/278 (46%), Gaps = 24/278 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I+V+D ND++P FE ++Y V+E + SG VLT+KA D D V Y +E+V+ T Sbjct: 3182 EISVMDENDNAPKFEKEKYVGKVKENSKSGEKVLTVKALDVDSEHFGAVSYELEIVSETT 3241 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + F I+ +G +L S+D EK+ +Y + V A D P Sbjct: 3242 TDTPVL-------------PFAINS-NGDVLISQSIDYEKIKKYNLKVIAKDGGRP---P 3284 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L S A + +++ D+ND+ P F + T V E ++ + K +D D N A Sbjct: 3285 LRSEALLEIHVEDENDHAPTFDDCNMTALVQEGEAIGHR--LLKFSVSDLDGPKNGAPFT 3342 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I G+ F ++ ++ K L+Y + Y L + A+D ++ L I IR Sbjct: 3343 VEIQGDGAKSFKVNE-KLELLTAKKLEYRKKDKYLLTVIAKD--VKGKTTDCPLTIFIRQ 3399 Query: 250 VNDNAPRFYTSLFQESVSEN-VPIGYSIVRVQAYDADE 286 + +AP Q + +N +P G I R++A D DE Sbjct: 3400 TSRHAPTMKPMKIQINTLQNELPEGI-IGRLKASDEDE 3436 Score = 86.6 bits (205), Expect = 9e-15 Identities = 148/696 (21%), Positives = 280/696 (40%), Gaps = 80/696 (11%) Query: 240 TTQLLINIRDVNDNAPRFYTSL--FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297 T ++ + + D ND +P F ++ + +++ +++RV+A DAD G+N+ + +++ Sbjct: 136 TARIHLRVIDRNDASPVFLVGEQGYEAEIDDDLEPFSTVLRVEASDADIGINSAIYFSLV 195 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTAT---------DGGDPPRSA 348 ++ + ++P +GWV + L KY L V + D + S Sbjct: 196 NRSHD------FIVEPVTGWVRS---LRHVKPGKYSLKVKSEDRASRLYYFDENEVQPSW 246 Query: 349 TATXXXXXXXXXXXXXXFMPGQYEV--------ELAE----DEPPGTPVVTLTATDADED 396 TA + Q ++ +LA + P +V L + + Sbjct: 247 TADVLITVRETKPKPRRILVDQRKINPNILNNRQLAAIITLKDSPNDAIVGLKGNEKEHW 306 Query: 397 NRLHYEITG--GNTRGRFSITSQNGRGL---ITVAQPLDFKQERRYVLTVSATDSGGRSD 451 + E+ G G R+ + ++NG + V + RR ++S ++ Sbjct: 307 FEVEPEVVGNDGTKELRWMLYAKNGSQVPKNTNVTLTIGEDYIRRSGFSISKKPVIPTNE 366 Query: 452 TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE 511 T +QI A + +N T E APIG + ++ + + I YSL E Sbjct: 367 TVTIQIERL-AEHLIRFLDNEKLTLKTDEMAPIGRILYRMNVNVENPDDVSLIRYSL--E 423 Query: 512 ISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571 S + + F I + G + + ++R Y V A G+ DV I + Sbjct: 424 YSKSDLPNATLPFAIGSKNGILRVSAKINRSERV-YNFKVIASLHGINEKLAEKDVSIEI 482 Query: 572 VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK-------D 624 +D ND+ PVF + + G + +V ATD D G NG+I Y+ + + Sbjct: 483 LDSNDHAPVFSAKWMRQTPIVIGKPGDVLVKVDATDQDEGENGKIVYKFTSELPLEINAN 542 Query: 625 REEGSFVIDPASG------VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678 E + V P G V + L ++ +L P + +I+ E Sbjct: 543 TGEITLVEVPKKGNSWPATVWAIDLGLPLSRMSALNLMFYKNGTKIPAKPKPIIIQ---E 599 Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK--GGDDSNSFS 736 N PVF S ++E++PIGT + +++A+D D G N + Y I G + Sbjct: 600 SENKHSPVFSSFPEIVEVTEDAPIGTVVAKLQANDEDTGYNGFIRYVIHDIAGSSHEVLT 659 Query: 737 LETRQG-----SDKAEL------VTMVDLDY----ESPRKKYELVIRA--ASPPLWNDVR 779 ++ + G SD ++L V V + Y S ++L + A A P+ + V+ Sbjct: 660 VDEQSGEITVASDLSKLMKEKLEVLDVQVHYIKHVTSNISNFQLKVSAIDAGTPVKSSVK 719 Query: 780 -VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNN-- 836 +++ + DVN+++P + ++ P +V A D D + + + GNN Sbjct: 720 TMKLRIKDVNNHSPQFDEVSYYLRISENEKPGKDIFKVTANDFDGGNNGKIKFSLGNNQE 779 Query: 837 -ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 +++I ++ TG + L L+ + T + +D Sbjct: 780 KSSVISIDAKTGIVKLLKSLDREDQDVHTFAIIASD 815 Score = 67.3 bits (157), Expect = 6e-09 Identities = 42/132 (31%), Positives = 76/132 (57%), Gaps = 10/132 (7%) Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQF--SEKTYTVSVDED 162 L+RE Y +LVKA + +S+ L +TA IH+ +ID ND P F E+ Y +D+D Sbjct: 109 LNRELKDFYDILVKAMCKRRDLSN-LETTARIHLRVIDRNDASPVFLVGEQGYEAEIDDD 167 Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222 + + +++A+DAD+G NSAI ++++ N F ++ ++G V++L + + Sbjct: 168 LEPFST--VLRVEASDADIGINSAIYFSLV--NRSHDFIVEPVTG---WVRSLRHVKPGK 220 Query: 223 YRLVIRAQDGGS 234 Y L ++++D S Sbjct: 221 YSLKVKSEDRAS 232 Score = 54.8 bits (126), Expect = 3e-05 Identities = 34/107 (31%), Positives = 60/107 (56%), Gaps = 7/107 (6%) Query: 539 LDRETMSGYLLTVTA--RDGGVPSLSDTTDVEISVVDVNDNEPVFK--QQLYTANIMEDA 594 L+RE Y + V A + + +L T + + V+D ND PVF +Q Y A I +D Sbjct: 109 LNRELKDFYDILVKAMCKRRDLSNLETTARIHLRVIDRNDASPVFLVGEQGYEAEIDDDL 168 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641 ++V +V A+DAD+G+N I++ L + + F+++P +G +R+ Sbjct: 169 EPFSTVLRVEASDADIGINSAIYFSLVNRSHD---FIVEPVTGWVRS 212 Score = 49.6 bits (113), Expect = 0.001 Identities = 68/303 (22%), Positives = 111/303 (36%), Gaps = 38/303 (12%) Query: 1310 CPEKRSRCSSAPCYNGAEC--SDLWDTYICDCKEGHTGKDCA----DSTGP-----PWRF 1358 C + ++C+ +PC C S TY C C G G C+ + G Sbjct: 3682 CEVETNQCAKSPCEQWQLCIPSVHNSTYECVCPLGMEGDKCSVPSCQNDGKCLEEAELSV 3741 Query: 1359 GGDGMLSFNPLLRPIQLPWLNALSIRTRQRDAFVM---------SIQLKSGLLHYSYNGE 1409 GGDG + L I+ + ++T + +M ++L +G Y +N Sbjct: 3742 GGDGYFEIS-LSNEIETRMELEIELKTTTHNGIIMWSRGKRDFHMLRLVNGTPEYHWNAG 3800 Query: 1410 T---MYLPMATLSDGAWHRIEIKWLGTDISVTV-DYGLRTVLMPMLANKIQGQYIGKILI 1465 T + ++ DG WHRI I +TV D L+ P+ + I + L+ Sbjct: 3801 TGTGIVTSKTSVVDGQWHRIAISRRQRRTRMTVDDEDLQEAFSPIGSTVINLHRYSQKLV 3860 Query: 1466 GGLDTTAGLLASDVGFFEGCIQDVRIGTAQSLLNRPTVR-ENVRDGCQ--SRADCMLSIC 1522 G G L V C + + + + L R ++ + GC + + C C Sbjct: 3861 LGAKVDDGELTDGV---SACFRTISVDGMKVLKTRQGMKLFGAQPGCSALTSSPCNDLPC 3917 Query: 1523 PPYSKCVTSWDSS-TCTCEAGRVGPQC---VSACELGPCGAA-RCVPDQTPKGYSCACEP 1577 C++ S C C + G C + C PC +C+P Y C C Sbjct: 3918 QHAGTCISQGKSHFKCECPSRYSGNVCEIDLEPCASSPCPTGIQCIPFY--NDYLCKCPN 3975 Query: 1578 GYT 1580 G+T Sbjct: 3976 GFT 3978 Score = 48.4 bits (110), Expect = 0.003 Identities = 86/377 (22%), Positives = 161/377 (42%), Gaps = 42/377 (11%) Query: 445 DSGGRSDTAMVQINITDANNYAPVF--ENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502 D TA + + + D N+ +PVF Y A + +D +TVL V A+D+D+GIN+ Sbjct: 129 DLSNLETTARIHLRVIDRNDASPVFLVGEQGYEAEIDDDLEPFSTVLRVEASDADIGINS 188 Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD-GGVPSL 561 I +SL + HD F++ P TG + + L Y L V + D Sbjct: 189 AIYFSLVNR-------SHD--FIVEPVTGWV---RSLRHVKPGKYSLKVKSEDRASRLYY 236 Query: 562 SDTTDVEIS-----VVDVNDNEP-----VFKQQLYTANIMEDALVGTSVS-QVGATDADV 610 D +V+ S ++ V + +P + Q+ NI+ + + ++ + DA V Sbjct: 237 FDENEVQPSWTADVLITVRETKPKPRRILVDQRKINPNILNNRQLAAIITLKDSPNDAIV 296 Query: 611 GLNG--RIH-YELDPK-----DREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 GL G + H +E++P+ +E +++ +G ++ ++ Sbjct: 297 GLKGNEKEHWFEVEPEVVGNDGTKELRWMLYAKNGSQVPKNTNVTLTIGEDYIRRSGFSI 356 Query: 663 GTPPQSST-VIVHIKIEDINDSPPVF-ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 P T V I+IE + + F +++ LT E +PIG + + + + + Sbjct: 357 SKKPVIPTNETVTIQIERLAEHLIRFLDNEKLTLKTDEMAPIGRILYRMNVNVENPDDVS 416 Query: 721 VVHYSIK-GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV--IRAASPPL-WN 776 ++ YS++ D + +L GS L ++ ++++ + + L Sbjct: 417 LIRYSLEYSKSDLPNATLPFAIGSKNGILRVSAKINRSERVYNFKVIASLHGINEKLAEK 476 Query: 777 DVRVEILVTDVNDNAPV 793 DV +EIL D ND+APV Sbjct: 477 DVSIEIL--DSNDHAPV 491 Score = 43.2 bits (97), Expect = 0.11 Identities = 14/32 (43%), Positives = 20/32 (62%) Query: 1317 CSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C+S+PC G +C ++ Y+C C G TGK C Sbjct: 3951 CASSPCPTGIQCIPFYNDYLCKCPNGFTGKHC 3982 Score = 41.9 bits (94), Expect = 0.25 Identities = 21/54 (38%), Positives = 35/54 (64%), Gaps = 2/54 (3%) Query: 11 INVLDCNDHSPVFEM--QQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 + V+D ND SPVF + Q YEA + + +TVL ++A+D DIG N+ + +++ Sbjct: 141 LRVIDRNDASPVFLVGEQGYEAEIDDDLEPFSTVLRVEASDADIGINSAIYFSL 194 >UniRef50_UPI000065CB4F Cluster: Protocadherin-9 precursor.; n=2; Euteleostomi|Rep: Protocadherin-9 precursor. - Takifugu rubripes Length = 1011 Score = 285 bits (698), Expect = 2e-74 Identities = 194/623 (31%), Positives = 302/623 (48%), Gaps = 31/623 (4%) Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195 I + + D NDN P F +S+ E+ + N A ATD D G NS +Y +I G Sbjct: 129 IKIIVKDTNDNAPMFPSPVINISIPENTLI--NSRFAIPSATDPDTGPNSVHKYELINGQ 186 Query: 196 TQMQFSI-DSLSGD----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + I ++ G+ + + + LD EQ +Y + I+ +DGGSP +S+T L + + DV Sbjct: 187 SAFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGSPQKSSTAILQVTVTDV 246 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F + + EN IG S+V++QA DAD G NAE+ Y + L Sbjct: 247 NDNRPVFKEGQIEVHIPENSAIGTSVVQLQATDADIGANAEIHYVFGTQVSPATKRL-FA 305 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX----XXXXXXXF 366 ++ SG + LDRE A ++L V A+DG P AT T Sbjct: 306 LNSTSGLITVQRPLDREETAIHKLSVLASDGSSSPARATVTINVTDVNDNPPNIDLRYII 365 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQNGRGLITV 425 P V L+E +P T + +T +D D D N + N + L+ Sbjct: 366 SPINGTVFLSEKDPINTKIALITVSDKDTDINGKVICFIEKDVPFHLKAVYDN-QYLLET 424 Query: 426 AQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 + LD++ + Y + A+DSG S TA+V++ + D N+ AP+F +V E+ Sbjct: 425 SALLDYEGTKEYNFKIVASDSGKPSLNQTALVRVRLEDENDNAPIFTQPVIELAVMENNK 484 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 + +SATD D G NA+I Y L S F ++ +TG +T +++ DRE Sbjct: 485 RDLFLTTISATDEDSGKNAEIVYQLGPNAS---------FFDLDRKTGVLTASRVFDRED 535 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 +L TVTARD G P L V ++V+D NDN P F + + E+ ++V + Sbjct: 536 QDRFLFTVTARDNGTPPLQTQATVIVTVLDENDNNPKFTHNHFQFFVSENLPKYSTVGVI 595 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 TD+D G N + + D E +F++DP SGVI++N + DRE +++ A+D G Sbjct: 596 TVTDSDAGENAAVSLSI-LNDNE--NFILDPFSGVIKSNVSFDREQQSSYTFDVRAVDSG 652 Query: 664 TPPQSSTVIVHIKIEDINDSPP--VFESDCLTFYISENSPI-GTTIGEIRAHDPDEGPNA 720 PP SS V I + D+ND+ P ++ +F + S I G+ + E+ A D D G NA Sbjct: 653 RPPCSSAAKVTINVIDVNDNTPIVIYPPSNTSFKLVPLSSIPGSVVAEVFAVDGDTGMNA 712 Query: 721 VVHYSIKGGDDSNSFSLETRQGS 743 + Y+I G++ F ++ G+ Sbjct: 713 ELKYTIVSGNNKGLFRIDPVTGN 735 Score = 269 bits (660), Expect = 6e-70 Identities = 200/656 (30%), Positives = 306/656 (46%), Gaps = 51/656 (7%) Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 ++ I ++D NDNAP F + + S+ EN I A D D G N+ Y + + Sbjct: 128 KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPDTGPNSVHKYELINGQS 187 Query: 302 TGNVDLPITIDPRSGW--VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 +D+ T + W + LDRE + Y + + DGG P +S+TA Sbjct: 188 AFGLDIVETPEGEK-WPQLIVQQNLDREQKDTYVMKIKVEDGGSPQKSSTAILQVTVTDV 246 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEI---TGGNTRGRFSI 414 F GQ EV + E+ GT VV L ATDAD + +HY T+ F++ Sbjct: 247 NDNRPVFKEGQIEVHIPENSAIGTSVVQLQATDADIGANAEIHYVFGTQVSPATKRLFAL 306 Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFE---- 470 S + GLITV +PLD ++ + L+V A+D A V IN+TD N+ P + Sbjct: 307 NSTS--GLITVQRPLDREETAIHKLSVLASDGSSSPARATVTINVTDVNDNPPNIDLRYI 364 Query: 471 NAPYTASVF--EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528 +P +VF E PI T + +++ +D D IN ++ + ++ A +D Q+++ Sbjct: 365 ISPINGTVFLSEKDPINTKIALITVSDKDTDINGKVICFIEKDVPFHLKAVYDNQYLLE- 423 Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588 T+ LLD E Y + A D G PSL+ T V + + D NDN P+F Q + Sbjct: 424 ------TSALLDYEGTKEYNFKIVASDSGKPSLNQTALVRVRLEDENDNAPIFTQPVIEL 477 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648 +ME+ ++ + ATD D G N I Y+L P F +D +GV+ ++ DRE Sbjct: 478 AVMENNKRDLFLTTISATDEDSGKNAEIVYQLGP---NASFFDLDRKTGVLTASRVFDRE 534 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 A D GTPP + V + + D ND+ P F + F++SEN P +T+G Sbjct: 535 DQDRFLFTVTARDNGTPPLQTQATVIVTVLDENDNNPKFTHNHFQFFVSENLPKYSTVGV 594 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768 I D D G NA V SI +D+ +F L+ G K+ V D E + Y +R Sbjct: 595 ITVTDSDAGENAAVSLSIL--NDNENFILDPFSGVIKSN----VSFDREQ-QSSYTFDVR 647 Query: 769 AAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVP-------- 817 A PP + +V I V DVNDN P+ +I+ F + P +P Sbjct: 648 AVDSGRPPCSSAAKVTINVIDVNDNTPI-----VIYPPSNTSFKLVPLSSIPGSVVAEVF 702 Query: 818 AYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 A D D + +L+Y I+SGNN L ++ TG++TL + L + V+++D Sbjct: 703 AVDGDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAVTDIGLHRLVVNISD 758 Score = 237 bits (581), Expect = 2e-60 Identities = 197/716 (27%), Positives = 326/716 (45%), Gaps = 59/716 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I V D ND++P+F S+ E + ATD D G N+ +Y + Sbjct: 130 KIIVKDTNDNAPMFPSPVINISIPENTLINSRFAIPSATDPDTGPNSVHKYEL------- 182 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 +N + A + + L+ + +LDRE+ Y + +K D SP + Sbjct: 183 INGQSAFGLDIVETPEGE-------KWPQLIVQQNLDREQKDTYVMKIKVEDGGSP---Q 232 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 SSTA + V + D NDN P F E V + E+ ++ + + +++ATDAD+GAN+ I Y Sbjct: 233 KSSTAILQVTVTDVNDNRPVFKEGQIEVHIPENSAIGTS--VVQLQATDADIGANAEIHY 290 Query: 190 AI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG-GSPSRSNTTQLLI 245 + T+ F+++S SG +++ + LD E+ ++L + A DG SP+R+ T I Sbjct: 291 VFGTQVSPATKRLFALNSTSGLITVQRPLDREETAIHKLSVLASDGSSSPARATVT---I 347 Query: 246 NIRDVNDNAP----RFYTSLFQESV--SENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 N+ DVNDN P R+ S +V SE PI I + D D +N ++ +K Sbjct: 348 NVTDVNDNPPNIDLRYIISPINGTVFLSEKDPINTKIALITVSDKDTDINGKV-ICFIEK 406 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 D ++ + + TS LD E +Y + A+D G P + TA Sbjct: 407 DVPFHLK---AVYDNQYLLETSALLDYEGTKEYNFKIVASDSGKPSLNQTALVRVRLEDE 463 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG 419 F E+ + E+ + T++ATD D G F + + Sbjct: 464 NDNAPIFTQPVIELAVMENNKRDLFLTTISATDEDSGKNAEIVYQLGPNASFFDLDRKT- 522 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477 G++T ++ D + + R++ TV+A D+G A V + + D N+ P F + + Sbjct: 523 -GVLTASRVFDREDQDRFLFTVTARDNGTPPLQTQATVIVTVLDENDNNPKFTHNHFQFF 581 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 V E+ P +TV V++ TDSD G NA ++ S+ ++ ++ F+++P +G I +N Sbjct: 582 VSENLPKYSTVGVITVTDSDAGENAAVSLSILND---------NENFILDPFSGVIKSNV 632 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN---IMEDA 594 DRE S Y V A D G P S V I+V+DVNDN P+ + + + Sbjct: 633 SFDREQQSSYTFDVRAVDSGRPPCSSAAKVTINVIDVNDNTPIVIYPPSNTSFKLVPLSS 692 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654 + G+ V++V A D D G+N + Y + +G F IDP +G I + + H Sbjct: 693 IPGSVVAEVFAVDGDTGMNAELKYTI-VSGNNKGLFRIDPVTGNITLEEKPAVTDIGLHR 751 Query: 655 LKAVAIDGGTPPQSST-VIVHIKIED-INDSPPVFESDCLTFYISENSPIGTTIGE 708 L D G P T V+V + + D + +S +++ T +PI IGE Sbjct: 752 LVVNISDLGYPKSLHTLVLVFLYVNDTVGNSTLIYDLIRRTM----ETPIDRNIGE 803 Score = 88.2 bits (209), Expect = 3e-15 Identities = 78/302 (25%), Positives = 137/302 (45%), Gaps = 20/302 (6%) Query: 590 IMEDALVGTSVSQ--VGATDADVGLNGRIHYELDPKDREEGSFVIDPASG-VIRTNKALD 646 + E+ L+G + T+A G++ + Y L K + + ++G + T+ +D Sbjct: 36 LQENVLIGNIPKDLNISHTNAATGVSANLVYRLVSKAGDNPLVRVLSSTGEIFTTSNRID 95 Query: 647 RESVAT----HDLK-AVAIDGGTPPQSSTVIVHIKI--EDINDSPPVFESDCLTFYISEN 699 RE + D + + I+ P ++ IKI +D ND+ P+F S + I EN Sbjct: 96 REKLCPGPSFEDSECSFEIEVVILPNDYFRLIKIKIIVKDTNDNAPMFPSPVINISIPEN 155 Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL-ETRQGSDKAELVTMVDLDYES 758 + I + A DPD GPN+V Y + G + + ET +G +L+ +LD E Sbjct: 156 TLINSRFAIPSATDPDTGPNSVHKYELINGQSAFGLDIVETPEGEKWPQLIVQQNLDREQ 215 Query: 759 PRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR 815 + Y + I+ SP + +++ VTDVNDN PV K+ QI + ++ + Sbjct: 216 -KDTYVMKIKVEDGGSPQKSSTAILQVTVTDVNDNRPVFKEGQIEVHIPENSAIGTSVVQ 274 Query: 816 VPAYDADVTDKLQYRILSGNNAN-----LILLNETTGSMTLSPQLNTNVPKLATMEVSVT 870 + A DAD+ + + G + L LN T+G +T+ L+ + + V + Sbjct: 275 LQATDADIGANAEIHYVFGTQVSPATKRLFALNSTSGLITVQRPLDREETAIHKLSVLAS 334 Query: 871 DG 872 DG Sbjct: 335 DG 336 >UniRef50_Q4SVM9 Cluster: Chromosome 1 SCAF13750, whole genome shotgun sequence; n=11; Clupeocephala|Rep: Chromosome 1 SCAF13750, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 4362 Score = 281 bits (688), Expect = 3e-73 Identities = 249/884 (28%), Positives = 385/884 (43%), Gaps = 81/884 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I +LD ND++P E+ + +V E + GTTV + +D+D G N +V I Sbjct: 2241 KITILDLNDNAPEIEVTSFSKAVPEDSKPGTTVALISVSDKDSGVNGKVICFINEDVPFM 2300 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L+P + +++T++ LDRE ++Y + + A D Sbjct: 2301 LSPT------------------LQANMYSVVTKSVLDREHESKYDITITAKDAGD---QP 2339 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LSS TI V++ D NDN P+F YT V E+ + + A D D NS I Y Sbjct: 2340 LSSHRTISVSVSDVNDNSPEFVTNPYTFYVTENND--PGTTLFSVSAQDCDERDNSLISY 2397 Query: 190 AIIGGNTQMQ-----FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 II Q Q +I+S +G +S +K+ D+E + ++ + A D GSPS S+ + Sbjct: 2398 NIIRNGNQHQAITSFLNINSENGQISALKSFDFEAQKMFQFQVVASDSGSPSLSSNVTVK 2457 Query: 245 INIRDVNDNAPRFYTSLFQ-------ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297 + I D NDNAP + E + NV G+ + +V+AYDAD G N L + + Sbjct: 2458 VFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFALQ 2517 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX- 356 + + L +D +G + T +A+++L++ D G+ SATAT Sbjct: 2518 E---VSDHSL-FGLDRYTGQIRTLRSFTETDEAEHKLVILVKDNGNVSLSATATVLVKLV 2573 Query: 357 ----XXXXXXXXXFMPGQY------------EVELAEDEPPGTPVVTLTATDADEDNRLH 400 F PG+ VE+ P G+ L + +R Sbjct: 2574 EPKEAFAASDCSKFCPGRRGRSPEDGLDVVRRVEIQIGHPVGSVAKDLGLDISTLADR-R 2632 Query: 401 YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ---ERRYVLTVSATDSGGRSDTAMVQI 457 + I G F + NG ++ V + +D ++ + L + V + Sbjct: 2633 FRIVPGPNHHLFQLNQDNG--VLYVGKNIDREELCDGTKVCLINLKIVVESPLEIHYVGV 2690 Query: 458 NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517 I D N++AP F + + E P GT + +A D D +Y LS + Sbjct: 2691 EIADVNDHAPSFPESEQRLEIAEHTPPGTRFQIHAARDPDAATLTVRSYKLSHNDCFDID 2750 Query: 518 AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577 ++ I + K LDRE + + LT+TA DGG PS S + ++ I V+D NDN Sbjct: 2751 IRESEEDKIP----FLVLKKPLDREQKAQHSLTLTALDGGNPSRSGSLNLTIEVLDTNDN 2806 Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDREEGSFVIDPA 635 PVF + +Y ++ E+A GT V Q+ ATD D GLNG I Y K + + +F +D Sbjct: 2807 RPVFSKDIYLVSLDENAQRGTLVVQLNATDLDEGLNGEIEYSFGKTQKKKVQDTFELDSV 2866 Query: 636 SGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695 +G IR +D E L A D G P ++ V IKI+DIND+ P E L+ Sbjct: 2867 TGEIRVKGNVDFEETEVFRLDIQASDKGHLPWTAESRVVIKIKDINDNRPEIEITSLSTS 2926 Query: 696 ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755 + E++ GT I I D D G N V I G F L + LVT LD Sbjct: 2927 VPEDAKPGTVISLISIRDKDSGLNGKVICKISG---DVPFDLTPSIEENMYSLVTKGRLD 2983 Query: 756 YESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP 812 E Y+++I A PPL + + V+DVNDN PV ++ P Sbjct: 2984 RERV-AHYDIIITATDCGDPPLSAVKSLTVYVSDVNDNRPVFNQNPFELYLVENNAPGAS 3042 Query: 813 FGRVPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTLSPQ 854 V A D D+ + + Y I+ G+ LLN+ T + ++ + Sbjct: 3043 IFSVSAVDDDLNENALVNYNIIRGDG----LLNDLTAFLNINSE 3082 Score = 250 bits (613), Expect = 3e-64 Identities = 230/824 (27%), Positives = 370/824 (44%), Gaps = 77/824 (9%) Query: 93 DGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSE 152 D S L+ + LDREK ++ + A D +P S T+ I ++++D NDN P FS Sbjct: 3333 DRTSAHLVLQKQLDREKQDVISLTLTALDGGNPPK---SGTSQIIISVLDINDNAPVFSR 3389 Query: 153 KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII--GGNTQMQ-FSIDSLSGDV 209 Y + E+I ++ + ATD D N+ I +++ G N + F ID SG + Sbjct: 3390 SLYKAQIPENIQAGTTVIV--LNATDEDKELNAEIEFSLRSKGQNDVLDLFRIDPKSGAI 3447 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269 + +DYE+ ++ + +A D G P S ++L+ + DVNDNAP + +V E+ Sbjct: 3448 LVNGKIDYEENPAFEIHAQASDKGQPPMSTDCKVLVEVLDVNDNAPEITVTPLLSTVKED 3507 Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT---SGQLDR 326 +G +I V D D G N + + + +P +D Y+ +G LDR Sbjct: 3508 AEVGTAIALVSVLDKDGGKNGIVRAAIAN-------HVPFKLDTNYKNYYSLVVNGALDR 3560 Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386 E+QA++ + + A D G PP S+T+T F+ + + E+ P G + Sbjct: 3561 ESQAQFNVTIVACDEGAPPLSSTSTVAVQVSDVNDNAPRFLEQAINIYVKENSPVGATMK 3620 Query: 387 TLTATDADED--NRLHYEITGGNTRGR---FSITSQNGRGLITVAQPLDFKQERRYVLTV 441 T+TA DAD D ++ Y N+ + I + G I Q D+++ + + V Sbjct: 3621 TITAVDADVDQSGQVRYSYLQRNSESQPLSSMININSETGDIVSLQSFDYEELKTFQFQV 3680 Query: 442 SATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499 ATDSG S V + I D N+ P APY+ E + TTV + + G Sbjct: 3681 QATDSGVPPLSSNVSVNVFILDENDNNPAI-LAPYS----EHGSVNTTV-SIEVVVVESG 3734 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 + Q + + + E+ + D + A++ LL T+ T DGG+ Sbjct: 3735 ADIQTPFRHNVPVKEESFS--DLNLYLLIAIVAVSAIFLLSLITLIAVRCHRT--DGGLG 3790 Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619 S S LY A I E+ GT+V + ATD D LN I + Sbjct: 3791 SRS----------------------LYKAQIPENTQAGTTVIVLNATDEDKELNAEIEFS 3828 Query: 620 LDPKDREE--GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 L K + + F IDP SG I N +D E ++ A A D G PP S+ V +++ Sbjct: 3829 LRSKGQNDVLDLFRIDPKSGAILVNGKIDYEENPAFEIHAQASDKGQPPMSTDCKVLVEV 3888 Query: 678 EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL 737 D+ND+ P L + E++ +GT I + D D G N +V +I + F L Sbjct: 3889 LDVNDNAPEITVTSLLSTVKEDAEVGTAIALVSVLDKDGGKNGIVRAAIA---NHVPFKL 3945 Query: 738 ETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVM 794 +T + LV LD ES + ++ + I A +PPL + V + V+DVNDNAP Sbjct: 3946 DTNY-KNYYSLVVNGALDRES-QAQFNVTIVACDEGAPPLSSTSTVAVQVSDVNDNAPRF 4003 Query: 795 KDFQIIFNNYKDCFPVG-PFGRVPAYDADV--TDKLQYRILSGNN-----ANLILLNETT 846 + Q I K+ PVG + A DADV + +++Y L N+ +++I +N T Sbjct: 4004 LE-QAINIYVKENSPVGATMKTITAVDADVDQSGQVRYSYLQSNSESQPLSSMININSET 4062 Query: 847 GSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITE 889 G + + K +V TD GV + + + ++V ++ E Sbjct: 4063 GDIVSLQSFDYEELKTFQFQVQATDSGVPPLSSNVSVNVFILDE 4106 Score = 243 bits (594), Expect = 6e-62 Identities = 212/809 (26%), Positives = 356/809 (44%), Gaps = 47/809 (5%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 ++V D ND+SP F Y V E GTT+ ++ A D D N+ + Y I Sbjct: 2348 VSVSDVNDNSPEFVTNPYTFYVTENNDPGTTLFSVSAQDCDERDNSLISYNI----IRNG 2403 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N A + I+ +G + S D E + V A+D SP L Sbjct: 2404 NQHQA----------ITSFLNINSENGQISALKSFDFEAQKMFQFQVVASDSGSP---SL 2450 Query: 131 SSTATIHVNIIDDNDN-----YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 SS T+ V I+D NDN YP S + + +V ++ K++A DAD+G N Sbjct: 2451 SSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGYNG 2510 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 + +A+ + F +D +G + +++ ++LVI +D G+ S S T +L+ Sbjct: 2511 WLLFALQEVSDHSLFGLDRYTGQIRTLRSFTETDEAEHKLVILVKDNGNVSLSATATVLV 2570 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPI-GYSIVR---VQAYDADEGVNAELTY---TMTD 298 + + + S F P G +VR +Q V +L T+ D Sbjct: 2571 KLVEPKEAFAASDCSKFCPGRRGRSPEDGLDVVRRVEIQIGHPVGSVAKDLGLDISTLAD 2630 Query: 299 KDYT---GNVDLPITIDPRSGWVYTSGQLDRET--QAKYQLLVTATDGGDPPRSATATXX 353 + + G ++ +G +Y +DRE L+ + P Sbjct: 2631 RRFRIVPGPNHHLFQLNQDNGVLYVGKNIDREELCDGTKVCLINLKIVVESPLEIHYVGV 2690 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRL--HYEITGGNTRGR 411 F + +E+AE PPGT A D D Y+++ + Sbjct: 2691 EIADVNDHAPS-FPESEQRLEIAEHTPPGTRFQIHAARDPDAATLTVRSYKLSHNDCFDI 2749 Query: 412 FSITSQNGR-GLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPV 468 S+ + + + +PLD +Q+ ++ LT++A D G RS + + I + D N+ PV Sbjct: 2750 DIRESEEDKIPFLVLKKPLDREQKAQHSLTLTALDGGNPSRSGSLNLTIEVLDTNDNRPV 2809 Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528 F Y S+ E+A GT V+ ++ATD D G+N +I YS + F ++ Sbjct: 2810 FSKDIYLVSLDENAQRGTLVVQLNATDLDEGLNGEIEYSFGKTQKKKV----QDTFELDS 2865 Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588 TG I +D E + L + A D G + + V I + D+NDN P + + Sbjct: 2866 VTGEIRVKGNVDFEETEVFRLDIQASDKGHLPWTAESRVVIKIKDINDNRPEIEITSLST 2925 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648 ++ EDA GT +S + D D GLNG++ ++ + + I+ + T LDRE Sbjct: 2926 SVPEDAKPGTVISLISIRDKDSGLNGKVICKISGDVPFDLTPSIEENMYSLVTKGRLDRE 2985 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 VA +D+ A D G PP S+ + + + D+ND+ PVF + Y+ EN+ G +I Sbjct: 2986 RVAHYDIIITATDCGDPPLSAVKSLTVYVSDVNDNRPVFNQNPFELYLVENNAPGASIFS 3045 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDS-NSFSLETRQGSDKAELVTMVDLDYESPRK-KYELV 766 + A D D NA+V+Y+I GD N + S+ ++ + D+E+ + ++++V Sbjct: 3046 VSAVDDDLNENALVNYNIIRGDGLLNDLTAFLNINSENGQISALKSFDFETLKTFQFQVV 3105 Query: 767 IR-AASPPLWNDVRVEILVTDVNDNAPVM 794 + SP L ++V V++ + D NDNAPV+ Sbjct: 3106 ASDSGSPSLSSNVTVKVFILDQNDNAPVI 3134 Score = 231 bits (566), Expect = 2e-58 Identities = 225/840 (26%), Positives = 361/840 (42%), Gaps = 82/840 (9%) Query: 4 PFCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 P +H + VLD NDHSP F + Q + E A G A D D + Y + Sbjct: 2017 PLEVHYVAVEVLDVNDHSPTFSVNQTRLEISESALPGARFQLQGAHDPDSDAYSIQLYKL 2076 Query: 63 ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122 L +D DG+ L LD+E +T+++ A D Sbjct: 2077 SQNEHFRLEVKDRGD---------------DGKIPVLYLHKPLDKETARSHTLVLTAADG 2121 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 P S T TI + ++D NDN P F++++Y + E+ + + ++ ATD D G Sbjct: 2122 GKPAR---SGTMTIKITVLDVNDNMPVFAKESYVAVLRENSPI--GTTVLQVNATDLDDG 2176 Query: 183 ANSAIRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239 N + Y+ + + F ID+ +G++ + +DYE Y + I+A D GS Sbjct: 2177 LNGEVVYSFGNNVNHRLRKLFEIDADTGEIIVKGQIDYEMKDRYEIDIKASDKGSAPLET 2236 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE-LTYTMTD 298 + I I D+NDNAP + F ++V E+ G ++ + D D GVN + + + D Sbjct: 2237 EKSVKITILDLNDNAPEIEVTSFSKAVPEDSKPGTTVALISVSDKDSGVNGKVICFINED 2296 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358 + L T+ V T LDRE ++KY + +TA D GD P S+ T Sbjct: 2297 VPFM----LSPTLQANMYSVVTKSVLDREHESKYDITITAKDAGDQPLSSHRTISVSVSD 2352 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DNRL--HYEITGGNTR----GR 411 F+ Y + E+ PGT + +++A D DE DN L + I GN Sbjct: 2353 VNDNSPEFVTNPYTFYVTENNDPGTTLFSVSAQDCDERDNSLISYNIIRNGNQHQAITSF 2412 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVF 469 +I S+NG+ I+ + DF+ ++ + V A+DSG S V++ I D N+ APV Sbjct: 2413 LNINSENGQ--ISALKSFDFEAQKMFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVI 2470 Query: 470 ---ENAPYTASVFEDAP----IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522 ++ +A E+ P G V V A D+D+G N + ++L E+S+ ++ Sbjct: 2471 LYPVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFAL-QEVSDHSL----- 2524 Query: 523 QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582 F ++ TG I T + + + L + +D G SLS T V + +V+ + Sbjct: 2525 -FGLDRYTGQIRTLRSFTETDEAEHKLVILVKDNGNVSLSATATVLVKLVEPKEAFAASD 2583 Query: 583 QQLY----TANIMEDAL-----VGTSVSQ-VGATDADVGLN----GRIHYELDPKDREEG 628 + ED L V + VG+ D+GL+ + + P Sbjct: 2584 CSKFCPGRRGRSPEDGLDVVRRVEIQIGHPVGSVAKDLGLDISTLADRRFRIVPGPNHH- 2642 Query: 629 SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI--VHIKIEDINDSPPV 686 F ++ +GV+ K +DRE + K I+ +S I V ++I D+ND P Sbjct: 2643 LFQLNQDNGVLYVGKNIDREELC-DGTKVCLINLKIVVESPLEIHYVGVEIADVNDHAPS 2701 Query: 687 FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG-SDK 745 F I+E++P GT A DPD V Y + D F ++ R+ DK Sbjct: 2702 FPESEQRLEIAEHTPPGTRFQIHAARDPDAATLTVRSYKLSHND---CFDIDIRESEEDK 2758 Query: 746 AE-LVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVM-KDFQII 800 LV LD E + ++ L + A +P + + I V D NDN PV KD ++ Sbjct: 2759 IPFLVLKKPLDREQ-KAQHSLTLTALDGGNPSRSGSLNLTIEVLDTNDNRPVFSKDIYLV 2817 Score = 222 bits (542), Expect = 1e-55 Identities = 190/669 (28%), Positives = 302/669 (45%), Gaps = 57/669 (8%) Query: 117 VKATDQASPVSDRLSSTATIHVNIIDDNDN-----YPQFSEKTYTVSVDEDISVTDNPVI 171 V A+D SP LSS T+ V I+D NDN YP S + + +V ++ Sbjct: 370 VVASDSGSP---SLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLV 426 Query: 172 AKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD 231 K++A DAD+G N + +A+ + F +D +G + +++ ++LVI +D Sbjct: 427 TKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTGQIRTLRSFTETDEAEHKLVILVKD 486 Query: 232 GGSPSRSNTTQLLINI----------------RDVNDNAPRFYTSLFQESVSENVPIGYS 275 G+ S S T +L+ + +D D+ FY + SVS I Sbjct: 487 NGNVSLSATATVLVKLVEPKEAFAASDVQSSAQDDEDSHVTFYLMITLGSVSVLFVISII 546 Query: 276 IVRVQAYDADE------GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329 ++ Y + + G + T+ + + LP D R LDRE Sbjct: 547 VLIAMQYRSGDKRYMLVGPRMSIGSTIVPGSHANTLVLP---DRRR--TNEERLLDREKL 601 Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389 ++ L++TA DGG+PPRS T F Y ++ E+ GT V+ + Sbjct: 602 REHHLILTAVDGGNPPRSGTLNVTVIVLDSNDNHPIFSQEVYSADVPENVAAGTSVIKVK 661 Query: 390 ATDADE--DNRLHYEITGGNTRGRFSITSQNGR-GLITVAQPLDFKQERRYVLTVSATDS 446 ATD DE + + Y G R F I N G I V +DF++ + L V ATD Sbjct: 662 ATDLDEGANGEIEYFFGGQQDRRTFDIFDLNKETGEIKVKGGIDFEKVEVFKLDVHATDK 721 Query: 447 GG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504 G S V I + D N+ AP E + V ED+ GT + ++S TD D G+N ++ Sbjct: 722 GQPPMSTDCTVIIKVLDQNDNAPQIEVTSLSNVVPEDSKPGTVISLISITDLDAGLNGKV 781 Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT 564 SLS + D + ++ + LDRE++S Y +T+TA D G P+LSD Sbjct: 782 MCSLSDN------SPFDLKPSFQENMYSLVLKQPLDRESVSHYDVTITATDCGQPALSDF 835 Query: 565 TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624 + I V DVNDN P + ++E+ G+ + V A+D D+ N I Y + ++ Sbjct: 836 KTLSIDVSDVNDNAPKYSHSPIELYLVENNAPGSQIFSVTASDKDLNENADISYHIIREE 895 Query: 625 REEG---SFV-IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680 +G +F+ I+ +G I K+ D E++ T + VA D G+P SS V V + I D Sbjct: 896 GGQGKNAAFLNINAENGQISALKSFDFETLKTFQFQVVASDSGSPSLSSNVTVKVFILDQ 955 Query: 681 NDSPPVF----ESDCLTFYISE---NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN 733 ND+ PV S+ + E N G + ++RA+D D G N + ++++ D + Sbjct: 956 NDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFALQEVSDHS 1015 Query: 734 SFSLETRQG 742 F L+ G Sbjct: 1016 LFGLDRYTG 1024 Score = 216 bits (527), Expect = 8e-54 Identities = 132/442 (29%), Positives = 227/442 (51%), Gaps = 21/442 (4%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDN-RLHYEITGGNTRGRFSITSQNGRGLIT 424 F Q +E++E PG A D D D + N R + + G I Sbjct: 1283 FSVNQTRLEISESALPGARFQLQGAHDPDSDAYSIQLYKLSQNEHFRLEVKDRGDDGKIP 1342 Query: 425 VA---QPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVF 479 V +PLD + R + L ++A D G RS T ++I + D N+ PVF Y A + Sbjct: 1343 VLYLHKPLDKETARSHTLVLTAADGGKPARSGTMTIKITVLDVNDNMPVFAKESYVAVLR 1402 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E++PIGTTVL V+ATD D G+N ++ YS + +++ + F I+ TG I + Sbjct: 1403 ENSPIGTTVLQVNATDLDDGLNGEVVYSFGNNVNHRL----RKLFEIDADTGEIIVKGQI 1458 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 D E Y + + A D G L V+I+++D+NDN P + ++ + ED+ GT+ Sbjct: 1459 DYEMKDRYEIDIKASDKGSAPLETEKSVKITILDLNDNAPEIEVTSFSKAVPEDSKPGTT 1518 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV----IRTNKALDRESVATHDL 655 V+ + +D D G+NG++ ++ E+ F++ P + T LDRE + +D+ Sbjct: 1519 VALISVSDKDSGVNGKVICFIN----EDVPFMLSPTLQANMYSVVTKSVLDREHESKYDI 1574 Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 A D G P SS + + + D+ND+ P F ++ TFY++EN+ GTT+ + A D D Sbjct: 1575 TITAKDAGDQPLSSHRTISVSVSDVNDNSPEFVTNPYTFYVTENNDPGTTLFSVSAQDCD 1634 Query: 716 EGPNAVVHYSI-KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIR-AASP 772 E N+++ Y+I + G+ + + S+ ++ + D+E+ + ++++V + SP Sbjct: 1635 ERDNSLISYNIIRNGNQHQAITSFLNINSENGQISALKSFDFEAQKMFQFQVVASDSGSP 1694 Query: 773 PLWNDVRVEILVTDVNDNAPVM 794 L ++V V++ + D NDNAPV+ Sbjct: 1695 SLSSNVTVKVFILDQNDNAPVI 1716 Score = 214 bits (523), Expect = 3e-53 Identities = 186/692 (26%), Positives = 306/692 (44%), Gaps = 38/692 (5%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREG-------ASSGTTVLTLKATDQDIGKNAEVEYTI 62 ++ +LD ND++PV EG ++G V ++A D DIG N + + + Sbjct: 387 KVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFAL 446 Query: 63 ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD- 121 + V+ +L D + + + +L + + + A TVLVK + Sbjct: 447 QEVSDHSLFGLDRYTGQIRTLRSFTETDEAEHKL-VILVKDNGNVSLSATATVLVKLVEP 505 Query: 122 -QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIA-KIKATDA 179 +A SD SS DD D++ F SV ++ +IA + ++ D Sbjct: 506 KEAFAASDVQSSAQ-------DDEDSHVTFYLMITLGSVSVLFVISIIVLIAMQYRSGDK 558 Query: 180 D---VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS 236 VG +I I+ G+ + + + LD E++R + L++ A DGG+P Sbjct: 559 RYMLVGPRMSIGSTIVPGSHANTLVLPDRRR-TNEERLLDREKLREHHLILTAVDGGNPP 617 Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 RS T + + + D NDN P F ++ V ENV G S+++V+A D DEG N E+ Y Sbjct: 618 RSGTLNVTVIVLDSNDNHPIFSQEVYSADVPENVAAGTSVIKVKATDLDEGANGEIEYFF 677 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 + D+ ++ +G + G +D E ++L V ATD G PP S T Sbjct: 678 GGQQDRRTFDI-FDLNKETGEIKVKGGIDFEKVEVFKLDVHATDKGQPPMSTDCTVIIKV 736 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSIT 415 + ED PGT + ++ TD D N N+ + Sbjct: 737 LDQNDNAPQIEVTSLSNVVPEDSKPGTVISLISITDLDAGLNGKVMCSLSDNSPFDLKPS 796 Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAP 473 Q + + QPLD + Y +T++ATD G SD + I+++D N+ AP + ++P Sbjct: 797 FQENMYSLVLKQPLDRESVSHYDVTITATDCGQPALSDFKTLSIDVSDVNDNAPKYSHSP 856 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV-INPQTGA 532 + E+ G+ + V+A+D D+ NA I+Y + I E + F+ IN + G Sbjct: 857 IELYLVENNAPGSQIFSVTASDKDLNENADISYHI---IREEGGQGKNAAFLNINAENGQ 913 Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT----- 587 I+ K D ET+ + V A D G PSLS V++ ++D NDN PV + + Sbjct: 914 ISALKSFDFETLKTFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAE 973 Query: 588 --ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645 I + G V++V A DAD+G NG + + L + + F +D +G IRT ++ Sbjct: 974 GLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFALQ-EVSDHSLFGLDRYTGQIRTLRSF 1032 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 A H L + D G S+T V +K+ Sbjct: 1033 TETDEAEHKLVILVKDNGNVSLSATATVLVKL 1064 Score = 213 bits (521), Expect = 4e-53 Identities = 195/755 (25%), Positives = 327/755 (43%), Gaps = 61/755 (8%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +F+++ +G L ++DRE++ T + + V + + V I D ND+ P Sbjct: 2643 LFQLNQDNGVLYVGKNIDREELCDGTKVCLINLKI--VVESPLEIHYVGVEIADVNDHAP 2700 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 F E + + E I + DA A +R + N I D Sbjct: 2701 SFPESEQRLEIAEHTPPGTRFQIHAARDPDA---ATLTVRSYKLSHNDCFDIDIRESEED 2757 Query: 209 ----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 + L K LD EQ + L + A DGG+PSRS + L I + D NDN P F ++ Sbjct: 2758 KIPFLVLKKPLDREQKAQHSLTLTALDGGNPSRSGSLNLTIEVLDTNDNRPVFSKDIYLV 2817 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 S+ EN G +V++ A D DEG+N E+ Y+ K V +D +G + G + Sbjct: 2818 SLDENAQRGTLVVQLNATDLDEGLNGEIEYSF-GKTQKKKVQDTFELDSVTGEIRVKGNV 2876 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 D E ++L + A+D G P +A + + ED PGT Sbjct: 2877 DFEETEVFRLDIQASDKGHLPWTAESRVVIKIKDINDNRPEIEITSLSTSVPEDAKPGTV 2936 Query: 385 VVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 + ++ D D + ++ +I+G +N L+T + LD ++ Y + ++ Sbjct: 2937 ISLISIRDKDSGLNGKVICKISGDVPFDLTPSIEENMYSLVTKGR-LDRERVAHYDIIIT 2995 Query: 443 ATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 ATD G +A+ + + ++D N+ PVF P+ + E+ G ++ VSA D D+ Sbjct: 2996 ATDCGDPPLSAVKSLTVYVSDVNDNRPVFNQNPFELYLVENNAPGASIFSVSAVDDDLNE 3055 Query: 501 NAQITYSLSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 NA + Y++ I + + + F+ IN + G I+ K D ET+ + V A D G P Sbjct: 3056 NALVNYNI---IRGDGLLNDLTAFLNINSENGQISALKSFDFETLKTFQFQVVASDSGSP 3112 Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYT-------ANIMEDALVGTSVSQVGATDADVGL 612 SLS V++ ++D NDN PV + + I + G V++V A DAD+G Sbjct: 3113 SLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGY 3172 Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672 NG + + L + + F +D +G IRT ++ H L + D G S+T Sbjct: 3173 NGWLLFALQ-EVSDHSLFGLDRYTGQIRTLRSFTETDETEHKLVILVKDNGNVSLSATAT 3231 Query: 673 VHIKIEDINDSPPVFES-DCLTFYISENSPIGTTIGEIRAHDPDE-----GPNAVVHYSI 726 V +K+ D V +S D + Y+ E + GT I+ D+ GP + +I Sbjct: 3232 VLVKLHHRPDCNAVSKSPDYTSKYVPETNYDGTLCHSIQYRSGDKRYMLVGPRMSIGSTI 3291 Query: 727 KGGDDSNSFSLETR-----QGSDKAELVTMVD-----------------LDYESPRKKYE 764 G +N+ L R +GS + E + ++ L + R+K + Sbjct: 3292 VPGSHANTLVLPDRRRTNEEGSHRCECIWLIQFLKKVIKTGDRTSAHLVLQKQLDREKQD 3351 Query: 765 LV------IRAASPPLWNDVRVEILVTDVNDNAPV 793 ++ + +PP ++ I V D+NDNAPV Sbjct: 3352 VISLTLTALDGGNPPKSGTSQIIISVLDINDNAPV 3386 Score = 213 bits (520), Expect = 6e-53 Identities = 160/558 (28%), Positives = 250/558 (44%), Gaps = 24/558 (4%) Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195 + V ++D ND+ P FS + + E S A D D A S Y + N Sbjct: 1269 VAVEVLDVNDHSPTFSVNQTRLEISE--SALPGARFQLQGAHDPDSDAYSIQLYKL-SQN 1325 Query: 196 TQMQFSIDSLSGD-----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + + D + L K LD E RS+ LV+ A DGG P+RS T + I + DV Sbjct: 1326 EHFRLEVKDRGDDGKIPVLYLHKPLDKETARSHTLVLTAADGGKPARSGTMTIKITVLDV 1385 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F + + EN PIG ++++V A D D+G+N E+ Y+ + + Sbjct: 1386 NDNMPVFAKESYVAVLRENSPIGTTVLQVNATDLDDGLNGEVVYSF-GNNVNHRLRKLFE 1444 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 ID +G + GQ+D E + +Y++ + A+D G P + Sbjct: 1445 IDADTGEIIVKGQIDYEMKDRYEIDIKASDKGSAPLETEKSVKITILDLNDNAPEIEVTS 1504 Query: 371 YEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 + + ED PGT V ++ +D D N + S T Q + L Sbjct: 1505 FSKAVPEDSKPGTTVALISVSDKDSGVNGKVICFINEDVPFMLSPTLQANMYSVVTKSVL 1564 Query: 430 DFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 D + E +Y +T++A D+G + S + ++++D N+ +P F PYT V E+ GTT Sbjct: 1565 DREHESKYDITITAKDAGDQPLSSHRTISVSVSDVNDNSPEFVTNPYTFYVTENNDPGTT 1624 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETMSG 546 + VSA D D N+ I+Y++ I N F+ IN + G I+ K D E Sbjct: 1625 LFSVSAQDCDERDNSLISYNI---IRNGNQHQAITSFLNINSENGQISALKSFDFEAQKM 1681 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT-------ANIMEDALVGTS 599 + V A D G PSLS V++ ++D NDN PV + + I + G Sbjct: 1682 FQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHL 1741 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 V++V A DAD+G NG + + L + + F +D +G IRT ++ A H L + Sbjct: 1742 VTKVRAYDADIGYNGWLLFALQ-EVSDHSLFGLDRYTGQIRTLRSFTETDEAEHKLVILV 1800 Query: 660 IDGGTPPQSSTVIVHIKI 677 D G S+T V +K+ Sbjct: 1801 KDNGNVSLSATATVLVKL 1818 Score = 202 bits (494), Expect = 8e-50 Identities = 180/646 (27%), Positives = 292/646 (45%), Gaps = 47/646 (7%) Query: 126 VSDRLSSTATI----HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKI-KATDAD 180 V R+S +TI H N + D E Y S+ E++ V VI + K D Sbjct: 1151 VGPRMSIGSTIVPGSHANTLVLPDRRRTNEELRY--SIPEELGV--GAVIGNVAKDLGLD 1206 Query: 181 VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDGGSPSRS 238 A +A + I+ G+++ F + + +G + + + +D E+V R+ VI + + Sbjct: 1207 ANALNARGFRIVSGSSEPPFQLSN-NGILHVNRIIDREEVCERAGACVINTKIV-LENPL 1264 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 + + + DVND++P F + + +SE+ G A+D D + Y ++ Sbjct: 1265 EVHYVAVEVLDVNDHSPTFSVNQTRLEISESALPGARFQLQGAHDPDSDAYSIQLYKLSQ 1324 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358 ++ D + +Y LD+ET + L++TA DGG P RS T T Sbjct: 1325 NEHFRLEVKDRGDDGKIPVLYLHKPLDKETARSHTLVLTAADGGKPARSGTMTIKITVLD 1384 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT-----RGRFS 413 F Y L E+ P GT V+ + ATD D+ + GN R F Sbjct: 1385 VNDNMPVFAKESYVAVLRENSPIGTTVLQVNATDLDDGLNGEVVYSFGNNVNHRLRKLFE 1444 Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFEN 471 I + G I V +D++ + RY + + A+D G V+I I D N+ AP E Sbjct: 1445 IDADTGE--IIVKGQIDYEMKDRYEIDIKASDKGSAPLETEKSVKITILDLNDNAPEIEV 1502 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 ++ +V ED+ GTTV ++S +D D G+N ++ ++ ++ F+++P Sbjct: 1503 TSFSKAVPEDSKPGTTVALISVSDKDSGVNGKVICFINEDVP----------FMLSPTLQ 1552 Query: 532 A----ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT 587 A + T +LDRE S Y +T+TA+D G LS + +SV DVNDN P F YT Sbjct: 1553 ANMYSVVTKSVLDREHESKYDITITAKDAGDQPLSSHRTISVSVSDVNDNSPEFVTNPYT 1612 Query: 588 ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG---SFV-IDPASGVIRTNK 643 + E+ GT++ V A D D N I Y + + SF+ I+ +G I K Sbjct: 1613 FYVTENNDPGTTLFSVSAQDCDERDNSLISYNIIRNGNQHQAITSFLNINSENGQISALK 1672 Query: 644 ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF----ESDCLTFYISE- 698 + D E+ + VA D G+P SS V V + I D ND+ PV S+ + E Sbjct: 1673 SFDFEAQKMFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEI 1732 Query: 699 --NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 N G + ++RA+D D G N + ++++ D + F L+ G Sbjct: 1733 PRNVNAGHLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTG 1778 Score = 202 bits (494), Expect = 8e-50 Identities = 180/646 (27%), Positives = 292/646 (45%), Gaps = 47/646 (7%) Query: 126 VSDRLSSTATI----HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKI-KATDAD 180 V R+S +TI H N + D E Y S+ E++ V VI + K D Sbjct: 1905 VGPRMSIGSTIVPGSHANTLVLPDRRRTNEELRY--SIPEELGV--GAVIGNVAKDLGLD 1960 Query: 181 VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDGGSPSRS 238 A +A + I+ G+++ F + + +G + + + +D E+V R+ VI + + Sbjct: 1961 ANALNARGFRIVSGSSEPPFQLSN-NGILHVNRIIDREEVCERAGACVINTKIV-LENPL 2018 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 + + + DVND++P F + + +SE+ G A+D D + Y ++ Sbjct: 2019 EVHYVAVEVLDVNDHSPTFSVNQTRLEISESALPGARFQLQGAHDPDSDAYSIQLYKLSQ 2078 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358 ++ D + +Y LD+ET + L++TA DGG P RS T T Sbjct: 2079 NEHFRLEVKDRGDDGKIPVLYLHKPLDKETARSHTLVLTAADGGKPARSGTMTIKITVLD 2138 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT-----RGRFS 413 F Y L E+ P GT V+ + ATD D+ + GN R F Sbjct: 2139 VNDNMPVFAKESYVAVLRENSPIGTTVLQVNATDLDDGLNGEVVYSFGNNVNHRLRKLFE 2198 Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFEN 471 I + G I V +D++ + RY + + A+D G V+I I D N+ AP E Sbjct: 2199 IDADTGE--IIVKGQIDYEMKDRYEIDIKASDKGSAPLETEKSVKITILDLNDNAPEIEV 2256 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 ++ +V ED+ GTTV ++S +D D G+N ++ ++ ++ F+++P Sbjct: 2257 TSFSKAVPEDSKPGTTVALISVSDKDSGVNGKVICFINEDVP----------FMLSPTLQ 2306 Query: 532 A----ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT 587 A + T +LDRE S Y +T+TA+D G LS + +SV DVNDN P F YT Sbjct: 2307 ANMYSVVTKSVLDREHESKYDITITAKDAGDQPLSSHRTISVSVSDVNDNSPEFVTNPYT 2366 Query: 588 ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG---SFV-IDPASGVIRTNK 643 + E+ GT++ V A D D N I Y + + SF+ I+ +G I K Sbjct: 2367 FYVTENNDPGTTLFSVSAQDCDERDNSLISYNIIRNGNQHQAITSFLNINSENGQISALK 2426 Query: 644 ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF----ESDCLTFYISE- 698 + D E+ + VA D G+P SS V V + I D ND+ PV S+ + E Sbjct: 2427 SFDFEAQKMFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEI 2486 Query: 699 --NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 N G + ++RA+D D G N + ++++ D + F L+ G Sbjct: 2487 PRNVNAGHLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTG 2532 Score = 200 bits (488), Expect = 4e-49 Identities = 166/595 (27%), Positives = 266/595 (44%), Gaps = 62/595 (10%) Query: 4 PFCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 P +H + VLD NDHSP F + Q + E A G A D D + Y + Sbjct: 1263 PLEVHYVAVEVLDVNDHSPTFSVNQTRLEISESALPGARFQLQGAHDPDSDAYSIQLYKL 1322 Query: 63 ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122 L +D DG+ L LD+E +T+++ A D Sbjct: 1323 SQNEHFRLEVKDRGD---------------DGKIPVLYLHKPLDKETARSHTLVLTAADG 1367 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 P S T TI + ++D NDN P F++++Y + E+ + + ++ ATD D G Sbjct: 1368 GKPAR---SGTMTIKITVLDVNDNMPVFAKESYVAVLRENSPI--GTTVLQVNATDLDDG 1422 Query: 183 ANSAIRYAIIGGNTQMQ----FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238 N + Y+ G N + F ID+ +G++ + +DYE Y + I+A D GS Sbjct: 1423 LNGEVVYSF-GNNVNHRLRKLFEIDADTGEIIVKGQIDYEMKDRYEIDIKASDKGSAPLE 1481 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 + I I D+NDNAP + F ++V E+ G ++ + D D GVN ++ + Sbjct: 1482 TEKSVKITILDLNDNAPEIEVTSFSKAVPEDSKPGTTVALISVSDKDSGVNGKVICFI-- 1539 Query: 299 KDYTGNVDLPITIDP----RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354 N D+P + P V T LDRE ++KY + +TA D GD P S+ T Sbjct: 1540 -----NEDVPFMLSPTLQANMYSVVTKSVLDREHESKYDITITAKDAGDQPLSSHRTISV 1594 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DNRL--HYEITGGNTRGR 411 F+ Y + E+ PGT + +++A D DE DN L + I GN Sbjct: 1595 SVSDVNDNSPEFVTNPYTFYVTENNDPGTTLFSVSAQDCDERDNSLISYNIIRNGNQHQA 1654 Query: 412 FS----ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNY 465 + I S+NG+ I+ + DF+ ++ + V A+DSG S V++ I D N+ Sbjct: 1655 ITSFLNINSENGQ--ISALKSFDFEAQKMFQFQVVASDSGSPSLSSNVTVKVFILDQNDN 1712 Query: 466 APVF---ENAPYTASVFEDAP----IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518 APV ++ +A E+ P G V V A D+D+G N + ++L E+S+ ++ Sbjct: 1713 APVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFALQ-EVSDHSL- 1770 Query: 519 HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 F ++ TG I T + + + L + +D G SLS T V + +V+ Sbjct: 1771 -----FGLDRYTGQIRTLRSFTETDEAEHKLVILVKDNGNVSLSATATVLVKLVE 1820 Score = 187 bits (455), Expect = 4e-45 Identities = 133/435 (30%), Positives = 212/435 (48%), Gaps = 35/435 (8%) Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 Y A + E+ GTTV+V++ATD D +NA+I +SL S+ N+ + F I+P++GAI Sbjct: 3795 YKAQIPENTQAGTTVIVLNATDEDKELNAEIEFSLRSKGQNDVL----DLFRIDPKSGAI 3850 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593 N +D E + + A D G P +S V + V+DVNDN P + + ED Sbjct: 3851 LVNGKIDYEENPAFEIHAQASDKGQPPMSTDCKVLVEVLDVNDNAPEITVTSLLSTVKED 3910 Query: 594 ALVGTSVSQVGATDADVGLNG--------RIHYELDPKDREEGSFVIDPASGVIRTNKAL 645 A VGT+++ V D D G NG + ++LD + S V+ N AL Sbjct: 3911 AEVGTAIALVSVLDKDGGKNGIVRAAIANHVPFKLDTNYKNYYSLVV---------NGAL 3961 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 DRES A ++ VA D G PP SST V +++ D+ND+ P F + Y+ ENSP+G T Sbjct: 3962 DRESQAQFNVTIVACDEGAPPLSSTSTVAVQVSDVNDNAPRFLEQAINIYVKENSPVGAT 4021 Query: 706 IGEIRAHDPDEGPNAVVHYS-IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764 + I A D D + V YS ++ +S S S+ ++V++ DYE K ++ Sbjct: 4022 MKTITAVDADVDQSGQVRYSYLQSNSESQPLSSMININSETGDIVSLQSFDYEE-LKTFQ 4080 Query: 765 LVIRAAS---PPLWNDVRVEILVTDVNDNAP-VMKDFQIIFNNYKDCFP----VGPF-GR 815 ++A PPL ++V V + + D NDN P ++ + + + P G F + Sbjct: 4081 FQVQATDSGVPPLSSNVSVNVFILDENDNNPAILAPYSEHGSVNSESIPYSAEAGYFVAK 4140 Query: 816 VPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-G 872 + A D D L Y + NL + +TG + +++ N K + V V+D G Sbjct: 4141 IRAVDLDSGYNALLSYHLSEPKGNNLFRMGTSTGEIRTKRRMSDNDLKSHPLVVLVSDNG 4200 Query: 873 VNEIKAMMQLSVRLI 887 + A + + V ++ Sbjct: 4201 EPSLSATVSIEVVVV 4215 Score = 184 bits (448), Expect = 3e-44 Identities = 136/486 (27%), Positives = 229/486 (47%), Gaps = 32/486 (6%) Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS 164 LDREK+ + +++ A D +P S T + V ++D NDN+P FS++ Y+ V E+++ Sbjct: 596 LDREKLREHHLILTAVDGGNPPR---SGTLNVTVIVLDSNDNHPIFSQEVYSADVPENVA 652 Query: 165 VTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS---GDVSLVKTLDYEQVR 221 + + K+KATD D GAN I Y G + F I L+ G++ + +D+E+V Sbjct: 653 AGTS--VIKVKATDLDEGANGEIEYFFGGQQDRRTFDIFDLNKETGEIKVKGGIDFEKVE 710 Query: 222 SYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA 281 ++L + A D G P S ++I + D NDNAP+ + V E+ G I + Sbjct: 711 VFKLDVHATDKGQPPMSTDCTVIIKVLDQNDNAPQIEVTSLSNVVPEDSKPGTVISLISI 770 Query: 282 YDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341 D D G+N ++ +++D DL + + LDRE+ + Y + +TATD Sbjct: 771 TDLDAGLNGKVMCSLSDNS---PFDLKPSFQENMYSLVLKQPLDRESVSHYDVTITATDC 827 Query: 342 GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRL 399 G P S T + E+ L E+ PG+ + ++TA+D D E+ + Sbjct: 828 GQPALSDFKTLSIDVSDVNDNAPKYSHSPIELYLVENNAPGSQIFSVTASDKDLNENADI 887 Query: 400 HYEIT---GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAM 454 Y I GG + + G I+ + DF+ + + V A+DSG S Sbjct: 888 SYHIIREEGGQGKNAAFLNINAENGQISALKSFDFETLKTFQFQVVASDSGSPSLSSNVT 947 Query: 455 VQINITDANNYAPVF---ENAPYTASVFEDAP----IGTTVLVVSATDSDVGINAQITYS 507 V++ I D N+ APV ++ +A E+ P G V V A D+D+G N + ++ Sbjct: 948 VKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFA 1007 Query: 508 LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567 L E+S+ ++ F ++ TG I T + + + L + +D G SLS T V Sbjct: 1008 LQ-EVSDHSL------FGLDRYTGQIRTLRSFTETDEAEHKLVILVKDNGNVSLSATATV 1060 Query: 568 EISVVD 573 + +V+ Sbjct: 1061 LVKLVE 1066 Score = 180 bits (439), Expect = 4e-43 Identities = 164/678 (24%), Positives = 291/678 (42%), Gaps = 62/678 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D ND++P F Q V+E + G T+ T+ A D D+ ++ +V Y+ +++ Sbjct: 3588 VQVSDVNDNAPRFLEQAINIYVKENSPVGATMKTITAVDADVDQSGQVRYSYLQRNSES- 3646 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P + + I+ +G +++ S D E++ + V+ATD P L Sbjct: 3647 QP-------------LSSMININSETGDIVSLQSFDYEELKTFQFQVQATDSGVP---PL 3690 Query: 131 SSTATIHVNIIDDNDNYPQ-FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 SS +++V I+D+NDN P + + SV+ +S+ + V+ N ++ Sbjct: 3691 SSNVSVNVFILDENDNNPAILAPYSEHGSVNTTVSI-EVVVVESGADIQTPFRHNVPVKE 3749 Query: 190 AIIGG-NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 N + +I ++S + L+ + VR +R DGG SRS Sbjct: 3750 ESFSDLNLYLLIAIVAVSA-IFLLSLITLIAVRCHR-----TDGGLGSRS---------- 3793 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 Y + E+ + + + A D D+ +NAE+ +++ K +DL Sbjct: 3794 --------LYKAQIPENTQAGTTV----IVLNATDEDKELNAEIEFSLRSKGQNDVLDL- 3840 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 IDP+SG + +G++D E +++ A+D G PP S Sbjct: 3841 FRIDPKSGAILVNGKIDYEENPAFEIHAQASDKGQPPMSTDCKVLVEVLDVNDNAPEITV 3900 Query: 369 GQYEVELAEDEPPGTPVVTLTATDAD-EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 + ED GT + ++ D D N + + + +N L+ V Sbjct: 3901 TSLLSTVKEDAEVGTAIALVSVLDKDGGKNGIVRAAIANHVPFKLDTNYKNYYSLV-VNG 3959 Query: 428 PLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 LD + + ++ +T+ A D G S T+ V + ++D N+ AP F V E++P+G Sbjct: 3960 ALDRESQAQFNVTIVACDEGAPPLSSTSTVAVQVSDVNDNAPRFLEQAINIYVKENSPVG 4019 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 T+ ++A D+DV + Q+ YS SN IN +TG I + + D E + Sbjct: 4020 ATMKTITAVDADVDQSGQVRYSYLQ--SNSESQPLSSMININSETGDIVSLQSFDYEELK 4077 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF------KQQLYTANIMEDALVGTS 599 + V A D GVP LS V + ++D NDN P + + +I A G Sbjct: 4078 TFQFQVQATDSGVPPLSSNVSVNVFILDENDNNPAILAPYSEHGSVNSESIPYSAEAGYF 4137 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 V+++ A D D G N + Y L + + F + ++G IRT + + + +H L + Sbjct: 4138 VAKIRAVDLDSGYNALLSYHLS-EPKGNNLFRMGTSTGEIRTKRRMSDNDLKSHPLVVLV 4196 Query: 660 IDGGTPPQSSTVIVHIKI 677 D G P S+TV + + + Sbjct: 4197 SDNGEPSLSATVSIEVVV 4214 Score = 175 bits (426), Expect = 1e-41 Identities = 120/376 (31%), Positives = 191/376 (50%), Gaps = 19/376 (5%) Query: 429 LDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD ++ R + L ++A D G RS T V + + D+N+ P+F Y+A V E+ GT Sbjct: 596 LDREKLREHHLILTAVDGGNPPRSGTLNVTVIVLDSNDNHPIFSQEVYSADVPENVAAGT 655 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 +V+ V ATD D G N +I Y + D +N +TG I +D E + Sbjct: 656 SVIKVKATDLDEGANGEIEYFFGGQQDRRTFDIFD----LNKETGEIKVKGGIDFEKVEV 711 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 + L V A D G P +S V I V+D NDN P + + + ED+ GT +S + T Sbjct: 712 FKLDVHATDKGQPPMSTDCTVIIKVLDQNDNAPQIEVTSLSNVVPEDSKPGTVISLISIT 771 Query: 607 DADVGLNGRIHYELD---PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 D D GLNG++ L P D + SF + S V++ + LDRESV+ +D+ A D G Sbjct: 772 DLDAGLNGKVMCSLSDNSPFDLKP-SFQENMYSLVLK--QPLDRESVSHYDVTITATDCG 828 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 P S + I + D+ND+ P + + Y+ EN+ G+ I + A D D NA + Sbjct: 829 QPALSDFKTLSIDVSDVNDNAPKYSHSPIELYLVENNAPGSQIFSVTASDKDLNENADIS 888 Query: 724 YSI---KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIR-AASPPLWNDV 778 Y I +GG N+ L ++ ++ + D+E+ + ++++V + SP L ++V Sbjct: 889 YHIIREEGGQGKNAAFLNIN--AENGQISALKSFDFETLKTFQFQVVASDSGSPSLSSNV 946 Query: 779 RVEILVTDVNDNAPVM 794 V++ + D NDNAPV+ Sbjct: 947 TVKVFILDQNDNAPVI 962 Score = 175 bits (425), Expect = 2e-41 Identities = 122/408 (29%), Positives = 197/408 (48%), Gaps = 25/408 (6%) Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 T D S + QLDRE Q L +TA DGG+PP+S T+ F Sbjct: 3331 TGDRTSAHLVLQKQLDREKQDVISLTLTALDGGNPPKSGTSQIIISVLDINDNAPVFSRS 3390 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT----GGN-TRGRFSITSQNGRGLIT 424 Y+ ++ E+ GT V+ L ATD D++ E + G N F I ++G I Sbjct: 3391 LYKAQIPENIQAGTTVIVLNATDEDKELNAEIEFSLRSKGQNDVLDLFRIDPKSGA--IL 3448 Query: 425 VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 V +D+++ + + A+D G S V + + D N+ AP P ++V EDA Sbjct: 3449 VNGKIDYEENPAFEIHAQASDKGQPPMSTDCKVLVEVLDVNDNAPEITVTPLLSTVKEDA 3508 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 +GT + +VS D D G N + ++++ + + ++ + ++ N LDRE Sbjct: 3509 EVGTAIALVSVLDKDGGKNGIVRAAIANHVPFKLDTNYKNYY-------SLVVNGALDRE 3561 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 + + + +T+ A D G P LS T+ V + V DVNDN P F +Q + E++ VG ++ Sbjct: 3562 SQAQFNVTIVACDEGAPPLSSTSTVAVQVSDVNDNAPRFLEQAINIYVKENSPVGATMKT 3621 Query: 603 VGATDADVGLNGRIHYELDPKDREE---GSFV-IDPASGVIRTNKALDRESVATHDLKAV 658 + A DADV +G++ Y ++ E S + I+ +G I + ++ D E + T + Sbjct: 3622 ITAVDADVDQSGQVRYSYLQRNSESQPLSSMININSETGDIVSLQSFDYEELKTFQFQVQ 3681 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706 A D G PP SS V V++ I D ND+ P L Y SE+ + TT+ Sbjct: 3682 ATDSGVPPLSSNVSVNVFILDENDNNPAI----LAPY-SEHGSVNTTV 3724 Score = 162 bits (394), Expect = 1e-37 Identities = 108/345 (31%), Positives = 169/345 (48%), Gaps = 28/345 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+VLD ND++PVF Y+A + E +GTTV+ L ATD+D NAE+E+++ Sbjct: 3375 ISVLDINDNAPVFSRSLYKAQIPENIQAGTTVIVLNATDEDKELNAEIEFSLR------- 3427 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 V D+FRID +SGA+L +D E+ + + +A+D+ P + Sbjct: 3428 ---------SKGQNDVLDLFRIDPKSGAILVNGKIDYEENPAFEIHAQASDKGQP---PM 3475 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+ + V ++D NDN P+ + +V ED V IA + D D G N +R A Sbjct: 3476 STDCKVLVEVLDVNDNAPEITVTPLLSTVKEDAEV--GTAIALVSVLDKDGGKNGIVRAA 3533 Query: 191 IIGGNTQMQFSID-SLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 I + F +D + SLV LD E + + I A D G+P S+T+ + + + Sbjct: 3534 IA---NHVPFKLDTNYKNYYSLVVNGALDRESQAQFNVTIVACDEGAPPLSSTSTVAVQV 3590 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN-VD 306 DVNDNAPRF V EN P+G ++ + A DAD + ++ Y+ ++ + Sbjct: 3591 SDVNDNAPRFLEQAINIYVKENSPVGATMKTITAVDADVDQSGQVRYSYLQRNSESQPLS 3650 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 I I+ +G + + D E +Q V ATD G PP S+ + Sbjct: 3651 SMININSETGDIVSLQSFDYEELKTFQFQVQATDSGVPPLSSNVS 3695 Score = 158 bits (383), Expect = 2e-36 Identities = 135/495 (27%), Positives = 219/495 (44%), Gaps = 25/495 (5%) Query: 392 DADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ--ERRYVLTVSATDS-GG 448 DA+ N + I G++ F +++ G++ V + +D ++ ER ++ Sbjct: 1206 DANALNARGFRIVSGSSEPPFQLSNN---GILHVNRIIDREEVCERAGACVINTKIVLEN 1262 Query: 449 RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508 + V + + D N+++P F + E A G + A D D + Y L Sbjct: 1263 PLEVHYVAVEVLDVNDHSPTFSVNQTRLEISESALPGARFQLQGAHDPDSDAYSIQLYKL 1322 Query: 509 SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568 S NE + + + + +K LD+ET + L +TA DGG P+ S T ++ Sbjct: 1323 SQ---NEHFRLEVKDRGDDGKIPVLYLHKPLDKETARSHTLVLTAADGGKPARSGTMTIK 1379 Query: 569 ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDRE 626 I+V+DVNDN PVF ++ Y A + E++ +GT+V QV ATD D GLNG + Y + R Sbjct: 1380 ITVLDVNDNMPVFAKESYVAVLRENSPIGTTVLQVNATDLDDGLNGEVVYSFGNNVNHRL 1439 Query: 627 EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686 F ID +G I +D E +++ A D G+ P + V I I D+ND+ P Sbjct: 1440 RKLFEIDADTGEIIVKGQIDYEMKDRYEIDIKASDKGSAPLETEKSVKITILDLNDNAPE 1499 Query: 687 FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746 E + + E+S GTT+ I D D G N V I ++ F L ++ Sbjct: 1500 IEVTSFSKAVPEDSKPGTTVALISVSDKDSGVNGKVICFI---NEDVPFMLSPTLQANMY 1556 Query: 747 ELVTMVDLDYESPRKKYELVIR---AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN 803 +VT LD E KY++ I A PL + + + V+DVNDN+P F Sbjct: 1557 SVVTKSVLDREH-ESKYDITITAKDAGDQPLSSHRTISVSVSDVNDNSPEFVTNPYTFYV 1615 Query: 804 YKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNN-----ANLILLNETTGSMTLSPQLN 856 ++ P V A D D D + Y I+ N + + +N G ++ + Sbjct: 1616 TENNDPGTTLFSVSAQDCDERDNSLISYNIIRNGNQHQAITSFLNINSENGQISALKSFD 1675 Query: 857 TNVPKLATMEVSVTD 871 K+ +V +D Sbjct: 1676 FEAQKMFQFQVVASD 1690 Score = 158 bits (383), Expect = 2e-36 Identities = 135/495 (27%), Positives = 219/495 (44%), Gaps = 25/495 (5%) Query: 392 DADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ--ERRYVLTVSATDS-GG 448 DA+ N + I G++ F +++ G++ V + +D ++ ER ++ Sbjct: 1960 DANALNARGFRIVSGSSEPPFQLSNN---GILHVNRIIDREEVCERAGACVINTKIVLEN 2016 Query: 449 RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508 + V + + D N+++P F + E A G + A D D + Y L Sbjct: 2017 PLEVHYVAVEVLDVNDHSPTFSVNQTRLEISESALPGARFQLQGAHDPDSDAYSIQLYKL 2076 Query: 509 SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568 S NE + + + + +K LD+ET + L +TA DGG P+ S T ++ Sbjct: 2077 SQ---NEHFRLEVKDRGDDGKIPVLYLHKPLDKETARSHTLVLTAADGGKPARSGTMTIK 2133 Query: 569 ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDRE 626 I+V+DVNDN PVF ++ Y A + E++ +GT+V QV ATD D GLNG + Y + R Sbjct: 2134 ITVLDVNDNMPVFAKESYVAVLRENSPIGTTVLQVNATDLDDGLNGEVVYSFGNNVNHRL 2193 Query: 627 EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686 F ID +G I +D E +++ A D G+ P + V I I D+ND+ P Sbjct: 2194 RKLFEIDADTGEIIVKGQIDYEMKDRYEIDIKASDKGSAPLETEKSVKITILDLNDNAPE 2253 Query: 687 FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746 E + + E+S GTT+ I D D G N V I ++ F L ++ Sbjct: 2254 IEVTSFSKAVPEDSKPGTTVALISVSDKDSGVNGKVICFI---NEDVPFMLSPTLQANMY 2310 Query: 747 ELVTMVDLDYESPRKKYELVIR---AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN 803 +VT LD E KY++ I A PL + + + V+DVNDN+P F Sbjct: 2311 SVVTKSVLDREH-ESKYDITITAKDAGDQPLSSHRTISVSVSDVNDNSPEFVTNPYTFYV 2369 Query: 804 YKDCFPVGPFGRVPAYDADVTDK--LQYRILSGNN-----ANLILLNETTGSMTLSPQLN 856 ++ P V A D D D + Y I+ N + + +N G ++ + Sbjct: 2370 TENNDPGTTLFSVSAQDCDERDNSLISYNIIRNGNQHQAITSFLNINSENGQISALKSFD 2429 Query: 857 TNVPKLATMEVSVTD 871 K+ +V +D Sbjct: 2430 FEAQKMFQFQVVASD 2444 Score = 157 bits (381), Expect = 4e-36 Identities = 123/443 (27%), Positives = 195/443 (44%), Gaps = 37/443 (8%) Query: 151 SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII--GGNTQMQ-FSIDSLSG 207 S Y + E+ ++ + ATD D N+ I +++ G N + F ID SG Sbjct: 3791 SRSLYKAQIPENTQAGTTVIV--LNATDEDKELNAEIEFSLRSKGQNDVLDLFRIDPKSG 3848 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 + + +DYE+ ++ + +A D G P S ++L+ + DVNDNAP + +V Sbjct: 3849 AILVNGKIDYEENPAFEIHAQASDKGQPPMSTDCKVLVEVLDVNDNAPEITVTSLLSTVK 3908 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT---SGQL 324 E+ +G +I V D D G N + + + +P +D Y+ +G L Sbjct: 3909 EDAEVGTAIALVSVLDKDGGKNGIVRAAIAN-------HVPFKLDTNYKNYYSLVVNGAL 3961 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 DRE+QA++ + + A D G PP S+T+T F+ + + E+ P G Sbjct: 3962 DRESQAQFNVTIVACDEGAPPLSSTSTVAVQVSDVNDNAPRFLEQAINIYVKENSPVGAT 4021 Query: 385 VVTLTATDADED--NRLHYEITGGNTRGR---FSITSQNGRGLITVAQPLDFKQERRYVL 439 + T+TA DAD D ++ Y N+ + I + G I Q D+++ + + Sbjct: 4022 MKTITAVDADVDQSGQVRYSYLQSNSESQPLSSMININSETGDIVSLQSFDYEELKTFQF 4081 Query: 440 TVSATDSG--GRSDTAMVQINITDANNYAPVFENAPY-------TASVFEDAPIGTTVLV 490 V ATDSG S V + I D N+ P APY + S+ A G V Sbjct: 4082 QVQATDSGVPPLSSNVSVNVFILDENDNNPAI-LAPYSEHGSVNSESIPYSAEAGYFVAK 4140 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550 + A D D G NA ++Y LS N F + TG I T + + + + L Sbjct: 4141 IRAVDLDSGYNALLSYHLSEPKGNNL-------FRMGTSTGEIRTKRRMSDNDLKSHPLV 4193 Query: 551 VTARDGGVPSLSDTTDVEISVVD 573 V D G PSLS T +E+ VV+ Sbjct: 4194 VLVSDNGEPSLSATVSIEVVVVE 4216 Score = 154 bits (374), Expect = 3e-35 Identities = 116/359 (32%), Positives = 168/359 (46%), Gaps = 16/359 (4%) Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584 ++ P +LLDRE + + L +TA DGG P S T +V + V+D NDN P+F Q+ Sbjct: 582 LVLPDRRRTNEERLLDREKLREHHLILTAVDGGNPPRSGTLNVTVIVLDSNDNHPIFSQE 641 Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREE-GSFVIDPASGVIRTN 642 +Y+A++ E+ GTSV +V ATD D G NG I Y +DR F ++ +G I+ Sbjct: 642 VYSADVPENVAAGTSVIKVKATDLDEGANGEIEYFFGGQQDRRTFDIFDLNKETGEIKVK 701 Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 +D E V L A D G PP S+ V IK+ D ND+ P E L+ + E+S Sbjct: 702 GGIDFEKVEVFKLDVHATDKGQPPMSTDCTVIIKVLDQNDNAPQIEVTSLSNVVPEDSKP 761 Query: 703 GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762 GT I I D D G N V S+ D++ F L+ + LV LD ES Sbjct: 762 GTVISLISITDLDAGLNGKVMCSL---SDNSPFDLKPSFQENMYSLVLKQPLDRESV-SH 817 Query: 763 YELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY 819 Y++ I A P L + + I V+DVNDNAP I ++ P V A Sbjct: 818 YDVTITATDCGQPALSDFKTLSIDVSDVNDNAPKYSHSPIELYLVENNAPGSQIFSVTAS 877 Query: 820 DADVTDK--LQYRIL-----SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 D D+ + + Y I+ G NA + +N G ++ + K +V +D Sbjct: 878 DKDLNENADISYHIIREEGGQGKNAAFLNINAENGQISALKSFDFETLKTFQFQVVASD 936 Score = 154 bits (373), Expect = 4e-35 Identities = 109/354 (30%), Positives = 171/354 (48%), Gaps = 13/354 (3%) Query: 370 QYEVELAEDEPPGTPVVTLT---ATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 Q ++E+ GT V + D Y I G + F + ++G ++ V+ Sbjct: 20 QIRYSISEEVKEGTVVGNIAKDLGIDKASLKEREYRIVGASAEPLFRVNREDG--ILYVS 77 Query: 427 QPLDFKQ--ERRYVLTVSA-TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 + LD + E+ V ++ T + V I + D N+++P F +FE Sbjct: 78 KKLDREVICEKSNVCVINLKTVLENPLEIHYVAIEVLDVNDHSPTFPENEKRLEIFESTS 137 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 G + A D D G Y LS N+ ++ + + + K LDRE Sbjct: 138 TGARFQLQPARDPDGGQFTVQQYRLSP---NDHFRLEVKERGEDRKMPFLILQKALDREA 194 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 M + L +TA DGG P+ S T + I V+DVNDN PVF +++Y+A++ E++ GT V++V Sbjct: 195 MKEHKLVLTAVDGGRPAKSGTMGIIIQVLDVNDNSPVFTKEVYSASVNENSPPGTLVTRV 254 Query: 604 GATDADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 ATD D G NG I Y + R + F IDP +G I+ +D E ++++ A D Sbjct: 255 NATDLDEGANGDIIYSFGQEVDTRVKNKFSIDPKTGDIKVTGVIDFEENESYEIDVQASD 314 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 GT P S+ V IK++D+ND+PP E + + E+S IGTT+ I A D D Sbjct: 315 KGTIPLSTYRSVIIKVKDLNDNPPEIEITSFSKSVPEDSRIGTTVALISASDLD 368 Score = 148 bits (358), Expect = 3e-33 Identities = 126/483 (26%), Positives = 207/483 (42%), Gaps = 42/483 (8%) Query: 28 YEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQ 87 Y+A + E +GTTV+ L ATD+D NAE+E+++ V Sbjct: 3795 YKAQIPENTQAGTTVIVLNATDEDKELNAEIEFSLR----------------SKGQNDVL 3838 Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 D+FRID +SGA+L +D E+ + + +A+D+ P +S+ + V ++D NDN Sbjct: 3839 DLFRIDPKSGAILVNGKIDYEENPAFEIHAQASDKGQP---PMSTDCKVLVEVLDVNDNA 3895 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSID-SLS 206 P+ + + +V ED V IA + D D G N +R AI + F +D + Sbjct: 3896 PEITVTSLLSTVKEDAEV--GTAIALVSVLDKDGGKNGIVRAAIA---NHVPFKLDTNYK 3950 Query: 207 GDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 SLV LD E + + I A D G+P S+T+ + + + DVNDNAPRF Sbjct: 3951 NYYSLVVNGALDRESQAQFNVTIVACDEGAPPLSSTSTVAVQVSDVNDNAPRFLEQAINI 4010 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYT-MTDKDYTGNVDLPITIDPRSGWVYTSGQ 323 V EN P+G ++ + A DAD + ++ Y+ + + + I I+ +G + + Sbjct: 4011 YVKENSPVGATMKTITAVDADVDQSGQVRYSYLQSNSESQPLSSMININSETGDIVSLQS 4070 Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE---- 379 D E +Q V ATD G PP S+ + + E E Sbjct: 4071 FDYEELKTFQFQVQATDSGVPPLSSNVSVNVFILDENDNNPAILAPYSEHGSVNSESIPY 4130 Query: 380 --PPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435 G V + A D D + L Y ++ F + + G I + + + Sbjct: 4131 SAEAGYFVAKIRAVDLDSGYNALLSYHLSEPKGNNLFRMGTSTGE--IRTKRRMSDNDLK 4188 Query: 436 RYVLTVSATDSGGRSDTAMVQINI----TDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491 + L V +D+G S +A V I + + A+ P N P F D + + +V Sbjct: 4189 SHPLVVLVSDNGEPSLSATVSIEVVVVESGADIQTPFRHNVPMKEESFSDLNLYLLIAIV 4248 Query: 492 SAT 494 + + Sbjct: 4249 AVS 4251 Score = 127 bits (306), Expect = 5e-27 Identities = 85/292 (29%), Positives = 140/292 (47%), Gaps = 24/292 (8%) Query: 4 PFCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 P IH I VLD NDHSP F + + E S+G A D D G+ +Y Sbjct: 103 PLEIHYVAIEVLDVNDHSPTFPENEKRLEIFESTSTGARFQLQPARDPDGGQFTVQQYR- 161 Query: 63 ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122 L+P D D + L+ + +LDRE + + +++ A D Sbjct: 162 -------LSPNDHFRLEVKERGE-------DRKMPFLILQKALDREAMKEHKLVLTAVDG 207 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 P S T I + ++D NDN P F+++ Y+ SV+E+ ++ ++ ATD D G Sbjct: 208 GRPAK---SGTMGIIIQVLDVNDNSPVFTKEVYSASVNENSP--PGTLVTRVNATDLDEG 262 Query: 183 ANSAIRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239 AN I Y+ + + +FSID +GD+ + +D+E+ SY + ++A D G+ S Sbjct: 263 ANGDIIYSFGQEVDTRVKNKFSIDPKTGDIKVTGVIDFEENESYEIDVQASDKGTIPLST 322 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE 291 ++I ++D+NDN P + F +SV E+ IG ++ + A D D V ++ Sbjct: 323 YRSVIIKVKDLNDNPPEIEITSFSKSVPEDSRIGTTVALISASDLDSVVASD 374 Score = 122 bits (295), Expect = 1e-25 Identities = 84/313 (26%), Positives = 141/313 (45%), Gaps = 11/313 (3%) Query: 87 QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146 + +FR++ G L LDRE + + + V + + + ++D ND+ Sbjct: 62 EPLFRVNREDGILYVSKKLDREVICEKSNV--CVINLKTVLENPLEIHYVAIEVLDVNDH 119 Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206 P F E + + E S + A D D G + +Y + N + + Sbjct: 120 SPTFPENEKRLEIFESTSTGARFQLQP--ARDPDGGQFTVQQYRL-SPNDHFRLEVKERG 176 Query: 207 GD-----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261 D + L K LD E ++ ++LV+ A DGG P++S T ++I + DVNDN+P F + Sbjct: 177 EDRKMPFLILQKALDREAMKEHKLVLTAVDGGRPAKSGTMGIIIQVLDVNDNSPVFTKEV 236 Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321 + SV+EN P G + RV A D DEG N ++ Y+ ++ V +IDP++G + + Sbjct: 237 YSASVNENSPPGTLVTRVNATDLDEGANGDIIYSF-GQEVDTRVKNKFSIDPKTGDIKVT 295 Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381 G +D E Y++ V A+D G P S + + + ED Sbjct: 296 GVIDFEENESYEIDVQASDKGTIPLSTYRSVIIKVKDLNDNPPEIEITSFSKSVPEDSRI 355 Query: 382 GTPVVTLTATDAD 394 GT V ++A+D D Sbjct: 356 GTTVALISASDLD 368 Score = 120 bits (290), Expect = 4e-25 Identities = 103/326 (31%), Positives = 150/326 (46%), Gaps = 21/326 (6%) Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 S+ E+ GT VV D+GI+ SL A + F +N + G + + Sbjct: 24 SISEEVKEGT---VVGNIAKDLGIDKA---SLKEREYRIVGASAEPLFRVNREDGILYVS 77 Query: 537 KLLDRETMSGYL-LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 K LDRE + + V + + + V I V+DVND+ P F + I E Sbjct: 78 KKLDREVICEKSNVCVINLKTVLENPLEIHYVAIEVLDVNDHSPTFPENEKRLEIFESTS 137 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDR---EEGSFVIDPASGVIRTNKALDRESVAT 652 G A D D G Y L P D E D + KALDRE++ Sbjct: 138 TGARFQLQPARDPDGGQFTVQQYRLSPNDHFRLEVKERGEDRKMPFLILQKALDREAMKE 197 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 H L A+DGG P +S T+ + I++ D+ND+ PVF + + ++ENSP GT + + A Sbjct: 198 HKLVLTAVDGGRPAKSGTMGIIIQVLDVNDNSPVFTKEVYSASVNENSPPGTLVTRVNAT 257 Query: 713 DPDEGPNAVVHYSIKGGDDS---NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 D DEG N + YS D+ N FS++ + G K VT V +D+E + YE+ ++A Sbjct: 258 DLDEGANGDIIYSFGQEVDTRVKNKFSIDPKTGDIK---VTGV-IDFEE-NESYEIDVQA 312 Query: 770 ASP---PLWNDVRVEILVTDVNDNAP 792 + PL V I V D+NDN P Sbjct: 313 SDKGTIPLSTYRSVIIKVKDLNDNPP 338 Score = 88.6 bits (210), Expect = 2e-15 Identities = 73/279 (26%), Positives = 130/279 (46%), Gaps = 25/279 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D ND++P F Q V+E + G T+ T+ A D D+ ++ +V Y+ L + Sbjct: 3991 VQVSDVNDNAPRFLEQAINIYVKENSPVGATMKTITAVDADVDQSGQVRYSY-LQSNSES 4049 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P + + I+ +G +++ S D E++ + V+ATD P L Sbjct: 4050 QP-------------LSSMININSETGDIVSLQSFDYEELKTFQFQVQATDSGVPP---L 4093 Query: 131 SSTATIHVNIIDDNDNYP----QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 SS +++V I+D+NDN P +SE S S +AKI+A D D G N+ Sbjct: 4094 SSNVSVNVFILDENDNNPAILAPYSEHGSVNSESIPYSAEAGYFVAKIRAVDLDSGYNAL 4153 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 + Y + F + + +G++ + + ++S+ LV+ D G PS S T + + Sbjct: 4154 LSYHLSEPKGNNLFRMGTSTGEIRTKRRMSDNDLKSHPLVVLVSDNGEPSLSATVSIEVV 4213 Query: 247 IRD--VNDNAP-RFYTSLFQESVSE-NVPIGYSIVRVQA 281 + + + P R + +ES S+ N+ + +IV V A Sbjct: 4214 VVESGADIQTPFRHNVPMKEESFSDLNLYLLIAIVAVSA 4252 Score = 72.1 bits (169), Expect = 2e-10 Identities = 73/275 (26%), Positives = 119/275 (43%), Gaps = 37/275 (13%) Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT-------ANIMEDALVGTSVSQ 602 +V A D G PSLS V++ ++D NDN PV + + I + G V++ Sbjct: 369 SVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTK 428 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 V A DAD+G NG + + L + + F +D +G IRT ++ A H L + D Sbjct: 429 VRAYDADIGYNGWLLFALQ-EVSDHSLFGLDRYTGQIRTLRSFTETDEAEHKLVILVKDN 487 Query: 663 GTPPQSSTVIVHIKI---------EDINDSPPVFESDCLTFYISEN----------SPIG 703 G S+T V +K+ D+ S E +TFY+ S I Sbjct: 488 GNVSLSATATVLVKLVEPKEAFAASDVQSSAQDDEDSHVTFYLMITLGSVSVLFVISIIV 547 Query: 704 TTIGEIRAHDPD---EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760 + R+ D GP + +I G +N+ L R+ +++ L LD E R Sbjct: 548 LIAMQYRSGDKRYMLVGPRMSIGSTIVPGSHANTLVLPDRRRTNEERL-----LDREKLR 602 Query: 761 KKYELV--IRAASPPLWNDVRVEILVTDVNDNAPV 793 + + ++ + +PP + V ++V D NDN P+ Sbjct: 603 EHHLILTAVDGGNPPRSGTLNVTVIVLDSNDNHPI 637 Score = 57.2 bits (132), Expect = 6e-06 Identities = 60/205 (29%), Positives = 92/205 (44%), Gaps = 15/205 (7%) Query: 627 EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE--DINDSP 684 E F ++ G++ +K LDRE + V I+ T ++ I ++ IE D+ND Sbjct: 62 EPLFRVNREDGILYVSKKLDREVICEKSNVCV-INLKTVLENPLEIHYVAIEVLDVNDHS 120 Query: 685 PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ-GS 743 P F + I E++ G A DPD G V Y + D F LE ++ G Sbjct: 121 PTFPENEKRLEIFESTSTGARFQLQPARDPDGGQFTVQQYRLSPNDH---FRLEVKERGE 177 Query: 744 DKAE--LVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQ 798 D+ L+ LD E+ K+++LV+ A P + + I V DVNDN+PV + Sbjct: 178 DRKMPFLILQKALDREA-MKEHKLVLTAVDGGRPAKSGTMGIIIQVLDVNDNSPVFTK-E 235 Query: 799 IIFNNYKDCFPVGPF-GRVPAYDAD 822 + + + P G RV A D D Sbjct: 236 VYSASVNENSPPGTLVTRVNATDLD 260 Score = 39.1 bits (87), Expect = 1.7 Identities = 31/101 (30%), Positives = 50/101 (49%), Gaps = 8/101 (7%) Query: 650 VATHDLKAV-AIDGGTPPQSSTVIVHIKIEDINDSPPVF----ESDCLTFYISE---NSP 701 ++ DL +V A D G+P SS V V + I D ND+ PV S+ + E N Sbjct: 362 ISASDLDSVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVN 421 Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 G + ++RA+D D G N + ++++ D + F L+ G Sbjct: 422 AGHLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTG 462 >UniRef50_Q9BZA7 Cluster: Protocadherin-11 X-linked precursor; n=115; Euteleostomi|Rep: Protocadherin-11 X-linked precursor - Homo sapiens (Human) Length = 1347 Score = 281 bits (688), Expect = 3e-73 Identities = 210/677 (31%), Positives = 325/677 (48%), Gaps = 40/677 (5%) Query: 89 VFRIDGRSGALLTR-ASLDREKVARYTVLVKATDQASPVS---DRLSSTATIHVNIIDDN 144 + RI+ +G + T A +DREK+ + V+ D + I I D N Sbjct: 74 LIRIEEDTGEIFTTGARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDIN 133 Query: 145 DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS 204 DN P F +S+ E+ ++ + A D DVG N Y +I +Q F +D Sbjct: 134 DNAPLFPATVINISIPENSAINSKYTLPA--AVDPDVGINGVQNYELI--KSQNIFGLDV 189 Query: 205 LS---GD----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF 257 + GD + + K LD E+ +Y + ++ +DGG P RS+T L +++ D NDN P F Sbjct: 190 IETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVF 249 Query: 258 YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI-TIDPRSG 316 + + S+ EN P+G S+ ++ A DAD G NA++ ++ + + N+ + ++ +G Sbjct: 250 KETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFS--NLVSNIARRLFHLNATTG 307 Query: 317 WVYTSGQLDRETQAKYQLLVTATDGGDPPRSA----TATXXXXXXXXXXXXXXFMPGQYE 372 + LDRE ++LLV A+DGG P A T P Sbjct: 308 LITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDT 367 Query: 373 VELAEDEPPGTPVVTLTATDADEDNRLHYE-ITGGNTRGRFSITSQNGRGLITVAQPLDF 431 V L+E+ P T + +T TD D D+ T R N + L+ A LD+ Sbjct: 368 VVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSN-QFLLETAAYLDY 426 Query: 432 KQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 + + Y + + A D+G + +AM+ I + D N+ APVF + T S+ E+ G + Sbjct: 427 ESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLT 486 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 VSA D+D G NA+I Y L + E F ++ +TG +T K LDRE YL Sbjct: 487 KVSAMDADSGPNAKINYLLGPDAPPE--------FSLDCRTGMLTVVKKLDREKEDKYLF 538 Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 T+ A+D GVP L+ V +S++D NDN PVF Y + E+ +V + TD D Sbjct: 539 TILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPD 598 Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669 G N + L D E F ID +GVIR N + DRE ++ A DGG +SS Sbjct: 599 YGDNSAV--TLSILD-ENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSS 655 Query: 670 TVIVHIKIEDINDSPPVF---ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 + V I + D+ND+ PVF S+C + ++ GT + ++ A D D G NA V YSI Sbjct: 656 SAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSI 715 Query: 727 KGGDDSNSFSLETRQGS 743 GG+ + F+++ G+ Sbjct: 716 VGGNTRDLFAIDQETGN 732 Score = 262 bits (642), Expect = 1e-67 Identities = 204/689 (29%), Positives = 319/689 (46%), Gaps = 46/689 (6%) Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 I D+NDNAP F ++ S+ EN I A D D G+N Y + +D Sbjct: 129 IEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLD 188 Query: 307 LPITID-PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 + T + + + +LDRE + Y + V DGG P RS+TA Sbjct: 189 VIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPV 248 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYE---ITGGNTRGRFSITSQNGR 420 F + EV + E+ P GT V L ATDAD E+ ++H+ + R F + + G Sbjct: 249 FKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTG- 307 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAP------VFENAPY 474 LIT+ +PLD ++ + L V A+D G AMV +N+TD N+ P + Sbjct: 308 -LITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVND 366 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 T + E+ P+ T + +++ TD D N ++T EI QF++ Sbjct: 367 TVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLE------- 419 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 T LD E+ Y + + A D G P L+ + + I V D NDN PVF Q T +I E+ Sbjct: 420 TAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENN 479 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654 G +++V A DAD G N +I+Y L P E F +D +G++ K LDRE + Sbjct: 480 SPGIQLTKVSAMDADSGPNAKINYLLGPDAPPE--FSLDCRTGMLTVVKKLDREKEDKYL 537 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 +A D G PP +S V V + I D ND+ PVF + FY+ EN P T+G I DP Sbjct: 538 FTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDP 597 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---AS 771 D G N+ V SI D+++ F+++++ G + + D E ++ Y ++A Sbjct: 598 DYGDNSAVTLSIL--DENDDFTIDSQTGVIRPN----ISFDREK-QESYTFYVKAEDGGR 650 Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN--YKDCFPVGPFG----RVPAYDAD--V 823 + +V I V DVNDN PV F + +N Y+ P G +V A D D + Sbjct: 651 VSRSSSAKVTINVVDVNDNKPV---FIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGM 707 Query: 824 TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLS 883 +++Y I+ GN +L +++ TG++TL + + L + V D + Sbjct: 708 NAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVI 767 Query: 884 VRLITEEMLLNSITVRLNDMTAEQFLSPL 912 V L E + N+ + N++ + +P+ Sbjct: 768 VNLFVNESVTNATLI--NELVRKSTEAPV 794 Score = 215 bits (524), Expect = 2e-53 Identities = 170/613 (27%), Positives = 278/613 (45%), Gaps = 52/613 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 Q++V D ND+ PVF+ + E S+ E A GT+V L ATD DIG+NA++ ++ + ++ Sbjct: 236 QVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSN- 294 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + +F ++ +G + + LDRE+ + +LV A+D Sbjct: 295 ---------------IARRLFHLNATTGLITIKEPLDREETPNHKLLVLASD-----GGL 334 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDN-PV---IAKIKATDADVGANS 185 + + A + VN+ D NDN P + V++ + +++N P+ IA I TD D N Sbjct: 335 MPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDKDADHNG 394 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 + + ++ F + + + L++T LDYE + Y + + A D G P + + Sbjct: 395 RVTCFT---DHEIPFRLRPVFSNQFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAM 451 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 L I ++D NDNAP F S S+ EN G + +V A DAD G NA++ Y + Sbjct: 452 LFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGP---- 507 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 + ++D R+G + +LDRE + KY + A D G PP ++ T Sbjct: 508 -DAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDN 566 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422 F +Y + E+ P V +T TD D + ++ + F+I SQ G+ Sbjct: 567 SPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQT--GV 624 Query: 423 ITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS--- 477 I D +++ Y V A D G RS +A V IN+ D N+ PVF P S Sbjct: 625 IRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYEL 684 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 V GT V V A D+D G+NA++ YS+ + + F I+ +TG IT + Sbjct: 685 VLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDL-------FAIDQETGNITLME 737 Query: 538 LLDRETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 D + + + V A D G P SL V + V + N + +L + Sbjct: 738 KCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLI-NELVRKSTEAPVTP 796 Query: 597 GTSVSQVGATDAD 609 T ++ V + +D Sbjct: 797 NTEIADVSSPTSD 809 Score = 168 bits (409), Expect = 2e-39 Identities = 134/415 (32%), Positives = 198/415 (47%), Gaps = 23/415 (5%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 ++ I D N+ AP+F S+ E++ I + + +A D DVGIN Y L I + Sbjct: 125 IRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYEL---IKS 181 Query: 515 EAVAHHDQ-QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 + + D + + + K LDRE Y++ V DGG P S T +++SV D Sbjct: 182 QNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTD 241 Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD--PKDREEGSFV 631 NDN PVFK+ +I E+A VGTSV+Q+ ATDAD+G N +IH+ + F Sbjct: 242 TNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFH 301 Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691 ++ +G+I + LDRE H L +A DGG P + V+V+ + D+ND+ P + Sbjct: 302 LNATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVN--VTDVNDNVPSIDIRY 359 Query: 692 L------TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745 + T +SEN P+ T I I D D N V D F L S++ Sbjct: 360 IVNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFT---DHEIPFRLRP-VFSNQ 415 Query: 746 AELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN 802 L T LDYES K+Y + + AA PPL + I V D NDNAPV + + Sbjct: 416 FLLETAAYLDYES-TKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVS 474 Query: 803 NYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNA-NLILLNETTGSMTLSPQLN 856 ++ P +V A DAD + L G +A L+ TG +T+ +L+ Sbjct: 475 IPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLD 529 >UniRef50_Q4S3N9 Cluster: Chromosome 17 SCAF14747, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 17 SCAF14747, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1526 Score = 280 bits (687), Expect = 3e-73 Identities = 220/665 (33%), Positives = 331/665 (49%), Gaps = 59/665 (8%) Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +ST+T+ V ++D ND P F + Y VS+ E S+ + V+A++ +D D G N+ + Y Sbjct: 819 TSTSTLTVKVLDVNDETPTFDPRVYNVSLKE--SIPRDHVVARLACSDNDAGLNAELSYF 876 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG--SPSRSNTTQLLINIR 248 I GGN +FS+ G V V LD E +Y L++ A D G R+ T + + ++ Sbjct: 877 ITGGNQDGKFSVGFRDGIVRTVVGLDRETQAAYTLIVEAIDNGPAGSRRTGTATVFVEVQ 936 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 DVNDN P F + ++ SV E+VP G SI++VQA DAD+G N + Y + TGN + Sbjct: 937 DVNDNRPIFLQNSYETSVLESVPQGTSILQVQATDADQGENGSVLYRI----LTGNSNNL 992 Query: 309 ITIDPRSGWVYTSG--QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 +ID ++G V T G LDRET + + L V A + + ++ F Sbjct: 993 FSIDRQTGLV-TRGLRALDRETSSSHMLEVEAYNSDEGSMRSSVRVIIYVNDANDEVPVF 1051 Query: 367 MPGQY-EVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLI 423 QY + L E GT V+ + ATD D + + Y + G+ R +F + GL+ Sbjct: 1052 TQQQYNRLGLRETAGVGTSVIVVRATDPDTGDGGAVAYALVSGSDR-KFEVDVST--GLV 1108 Query: 424 TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 T LD++ + +T+ +N D A F +A Y AS+ E+ Sbjct: 1109 TTVDYLDYETKTTVYVTL---------------LNELDE---AVAFSSAGYEASLRENIA 1150 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 GT V+ V A +D +N Q+TY + S A+A F I+ TG IT LLDRE Sbjct: 1151 TGTEVIQVQAQSAD-NLN-QLTYRFDPDTSPAALA----LFKIDSVTGRITVTGLLDRER 1204 Query: 544 MSGYLLTVTARDGG-------VPSLSDTTDVEISVVDVNDNEPVFKQQLYTA-NIMEDAL 595 Y LTV A DGG + S S + V I+++D NDN PVF T+ +I E+ Sbjct: 1205 GDAYTLTVVADDGGPKKDSTVITSDSISQQVSITILDENDNSPVFDITSDTSVDITENTP 1264 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV--IDPASGVIRTNKALDRESVATH 653 +G V+ V A D D GLNG I++ L + ++ + ++ G + N LDRESV + Sbjct: 1265 MGEKVAVVLARDKDAGLNGLINFTLVAGNMKDVFKIKTVNHTYGEVYVNAPLDRESVDRY 1324 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD-CLTFYISENSPIGTTIGEIRAH 712 LK A D G+PP+ + + I I D+ND+ PV ES ISEN GT++ + A Sbjct: 1325 LLKVRATDNGSPPRHTDHSLTINILDVNDNAPVIESQKGYNVSISENVGGGTSVLRVMAT 1384 Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA--- 769 D D GPNA++ Y I G+ +F ++ G E+VT +++Y L + Sbjct: 1385 DRDIGPNAMLFYYITAGNQDLTFRMDRMTG----EMVTRPAPPDRERQQEYILTVTVEDD 1440 Query: 770 ASPPL 774 +PPL Sbjct: 1441 GTPPL 1445 Score = 267 bits (654), Expect = 3e-69 Identities = 219/675 (32%), Positives = 318/675 (47%), Gaps = 71/675 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND +P F+ + Y S++E V L +D D G NAE+ Y I T Sbjct: 826 VKVLDVNDETPTFDPRVYNVSLKESIPRDHVVARLACSDNDAGLNAELSYFI------TG 879 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +D F + R G + T LDRE A YT++V+A D P R Sbjct: 880 GNQDGK-------------FSVGFRDGIVRTVVGLDRETQAAYTLIVEAIDNG-PAGSRR 925 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + TAT+ V + D NDN P F + +Y SV E SV I +++ATDAD G N ++ Y Sbjct: 926 TGTATVFVEVQDVNDNRPIFLQNSYETSVLE--SVPQGTSILQVQATDADQGENGSVLYR 983 Query: 191 IIGGNTQMQFSIDSLSGDVSL-VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I+ GN+ FSID +G V+ ++ LD E S+ L + A + S ++ +++I + D Sbjct: 984 ILTGNSNNLFSIDRQTGLVTRGLRALDRETSSSHMLEVEAYNSDEGSMRSSVRVIIYVND 1043 Query: 250 VNDNAPRFYTSLFQE-SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 ND P F + + E +G S++ V+A D D G + Y + +G+ D Sbjct: 1044 ANDEVPVFTQQQYNRLGLRETAGVGTSVIVVRATDPDTGDGGAVAYALV----SGS-DRK 1098 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 +D +G V T LD ET K + VT + D A A F Sbjct: 1099 FEVDVSTGLVTTVDYLDYET--KTTVYVTLLNELD---EAVA---------------FSS 1138 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEI---TGGNTRGRFSITSQNGRGLITV 425 YE L E+ GT V+ + A AD N+L Y T F I S GR ITV Sbjct: 1139 AGYEASLRENIATGTEVIQVQAQSADNLNQLTYRFDPDTSPAALALFKIDSVTGR--ITV 1196 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAMV-------QINIT--DANNYAPVFENAPYTA 476 LD ++ Y LTV A D G + D+ ++ Q++IT D N+ +PVF+ T+ Sbjct: 1197 TGLLDRERGDAYTLTVVADDGGPKKDSTVITSDSISQQVSITILDENDNSPVFDITSDTS 1256 Query: 477 -SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 + E+ P+G V VV A D D G+N I ++L + + +N G + Sbjct: 1257 VDITENTPMGEKVAVVLARDKDAGLNGLINFTLVAGNMKDVFKIK----TVNHTYGEVYV 1312 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL-YTANIMEDA 594 N LDRE++ YLL V A D G P + I+++DVNDN PV + Q Y +I E+ Sbjct: 1313 NAPLDRESVDRYLLKVRATDNGSPPRHTDHSLTINILDVNDNAPVIESQKGYNVSISENV 1372 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA-LDRESVATH 653 GTSV +V ATD D+G N + Y + ++ +F +D +G + T A DRE + Sbjct: 1373 GGGTSVLRVMATDRDIGPNAMLFYYI-TAGNQDLTFRMDRMTGEMVTRPAPPDRERQQEY 1431 Query: 654 DLKAVAIDGGTPPQS 668 L D GTPP S Sbjct: 1432 ILTVTVEDDGTPPLS 1446 Score = 263 bits (644), Expect = 6e-68 Identities = 218/661 (32%), Positives = 315/661 (47%), Gaps = 64/661 (9%) Query: 218 EQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277 EQ+ Y L I A D G+ R++T+ L + + DVND P F ++ S+ E++P + + Sbjct: 799 EQIGLYYLRIIAYDAGNFPRTSTSTLTVKVLDVNDETPTFDPRVYNVSLKESIPRDHVVA 858 Query: 278 RVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVT 337 R+ D D G+NAEL+Y +T GN D ++ R G V T LDRETQA Y L+V Sbjct: 859 RLACSDNDAGLNAELSYFITG----GNQDGKFSVGFRDGIVRTVVGLDRETQAAYTLIVE 914 Query: 338 ATDGG--DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD- 394 A D G R+ TAT F+ YE + E P GT ++ + ATDAD Sbjct: 915 AIDNGPAGSRRTGTATVFVEVQDVNDNRPIFLQNSYETSVLESVPQGTSILQVQATDADQ 974 Query: 395 -EDNRLHYEITGGNTRGRFSITSQNGRGLITVA-QPLDFKQERRYVLTVSA--TDSGGRS 450 E+ + Y I GN+ FSI Q GL+T + LD + ++L V A +D G Sbjct: 975 GENGSVLYRILTGNSNNLFSIDRQT--GLVTRGLRALDRETSSSHMLEVEAYNSDEGSMR 1032 Query: 451 DTAMVQINITDANNYAPVFENAPYT-ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509 + V I + DAN+ PVF Y + E A +GT+V+VV ATD D G + Y+L Sbjct: 1033 SSVRVIIYVNDANDEVPVFTQQQYNRLGLRETAGVGTSVIVVRATDPDTGDGGAVAYAL- 1091 Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569 V+ D++F ++ TG +TT LD ET T V + Sbjct: 1092 -------VSGSDRKFEVDVSTGLVTTVDYLDYET--------------------KTTVYV 1124 Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE-- 627 ++++ D F Y A++ E+ GT V QV A AD LN ++ Y DP Sbjct: 1125 TLLNELDEAVAFSSAGYEASLRENIATGTEVIQVQAQSAD-NLN-QLTYRFDPDTSPAAL 1182 Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI--------VHIKIED 679 F ID +G I LDRE + L VA DGG P + STVI V I I D Sbjct: 1183 ALFKIDSVTGRITVTGLLDRERGDAYTLTVVADDGG-PKKDSTVITSDSISQQVSITILD 1241 Query: 680 INDSPPVFE-SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738 ND+ PVF+ + + I+EN+P+G + + A D D G N ++++++ G+ + F ++ Sbjct: 1242 ENDNSPVFDITSDTSVDITENTPMGEKVAVVLARDKDAGLNGLINFTLVAGNMKDVFKIK 1301 Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMK 795 T E+ LD ES +Y L +RA SPP D + I + DVNDNAPV++ Sbjct: 1302 T-VNHTYGEVYVNAPLDRESV-DRYLLKVRATDNGSPPRHTDHSLTINILDVNDNAPVIE 1359 Query: 796 DFQIIFNNYKDCFPVG-PFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLS 852 + + + G RV A D D+ L Y I +GN ++ TG M Sbjct: 1360 SQKGYNVSISENVGGGTSVLRVMATDRDIGPNAMLFYYITAGNQDLTFRMDRMTGEMVTR 1419 Query: 853 P 853 P Sbjct: 1420 P 1420 Score = 258 bits (633), Expect = 1e-66 Identities = 216/742 (29%), Positives = 337/742 (45%), Gaps = 54/742 (7%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F IDG G + LD E + Y + V ATDQ LS A + ++I D D P Sbjct: 38 FAIDGARGTVTVTKPLDYETTSAYQLTVNATDQDK--LRPLSRLANLAISITDVQDMDPI 95 Query: 150 FSEKTYTVSVDEDISVTDN------PV--------IAKIKATDADVGANSAIRYAIIGGN 195 F+ Y+ +++ED+ + P+ + KI A D D+G I Y I+ GN Sbjct: 96 FTNLPYSTNIEEDVPLISQTQTHLGPLHTALQGYEVRKITAMDQDLGRPRGIGYTIVSGN 155 Query: 196 TQMQFSIDSLSGDVSLVKTLDYEQV---RSYRLVIRA---QDGGSPSRSNT-TQLLINIR 248 T F++D +SG +++ LD E + L ++A ++ PS + T I + Sbjct: 156 TNSVFALDYISGSLTVSGQLDRENPLYSAGFTLTVKATELKEDRFPSDATVMTTFTILLI 215 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSI-VRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 D NDNAP+F +S ++ ++E +G+++ + +QA D DEGVN+ +T + Sbjct: 216 DKNDNAPKFNSSEYRLQITELAQVGFALPLFIQAEDKDEGVNSMFQVFLTGNNSEYFTLS 275 Query: 308 PITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 P + R+ + + LD E Y + A + A F Sbjct: 276 PTAVQGRADIRMRVAMPLDYEHIRSYSFSLYANESMSD-HVGFARVFIELINENDNRPIF 334 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 Y + L E+ PGT ++ + ATDAD + +FS+ + G ++ + Sbjct: 335 SKPLYNISLPENTAPGTSLLRILATDADAGTFGIVRYYFSDDPDQFSLDEETGWVILQAS 394 Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD++ RR+ LTV A D GG T +++N+ D N+ AP+F+ Y S+ E+ Sbjct: 395 --LDYELMRRFTLTVLARDGGGEETTGRIRVNVLDVNDNAPLFQKEAYVGSLRENEQAVQ 452 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 V + ATD D N +TY++ IS A + ++ T L + SG Sbjct: 453 PVARLRATDEDSPPNNFLTYTI---ISASAFPSYFSIIMVEGYAVISVTRPLDYEQVPSG 509 Query: 547 YL-LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG--TSVSQV 603 + L V +DGG P+L+ T V + V+D NDN P F + Y I E+ G +V V Sbjct: 510 MIHLEVMVKDGGSPALNSTVPVTVEVIDENDNPPEFSKSSYIVKIPENINAGEWATVLLV 569 Query: 604 GATDADVGL---NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 ATD D + Y L+ + F ++ SG I T LDRE + + L A+ Sbjct: 570 NATDLDASREFGQASLIYSLEGSSQ----FRLNSRSGEITTTALLDRELKSEYILIVRAV 625 Query: 661 DGGTPPQSSTVI--VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 DGG PQ T I V+I I DIND+ PV+ + + E SPI T + + A DPD G Sbjct: 626 DGGVGPQQKTGIATVNITILDINDNAPVWRDEPYHANVVEMSPINTDVISVLALDPDNGE 685 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY---ELVIRA---ASP 772 N V YSI ++ +++ + G + VT+ D + +PR ++I A SP Sbjct: 686 NGTVVYSI--SPENPFYTINSSTGKIRTSGVTL-DRESSNPRDAILMRTIIISAVDRGSP 742 Query: 773 PLWNDVRVEILVT--DVNDNAP 792 L + V D+NDN P Sbjct: 743 QLRASASTTVFVNLLDLNDNDP 764 Score = 254 bits (623), Expect = 2e-65 Identities = 223/734 (30%), Positives = 332/734 (45%), Gaps = 70/734 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGK--NAEVEYTIELVTA- 67 I++ D D P+F Y ++ E V + T +G A Y + +TA Sbjct: 84 ISITDVQDMDPIFTNLPYSTNIEED------VPLISQTQTHLGPLHTALQGYEVRKITAM 137 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKV---ARYTVLVKATDQAS 124 D VF +D SG+L LDRE A +T+ VKAT+ Sbjct: 138 DQDLGRPRGIGYTIVSGNTNSVFALDYISGSLTVSGQLDRENPLYSAGFTLTVKATELKE 197 Query: 125 PVSDRLSSTATIHVN----IIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD 180 DR S AT+ +ID NDN P+F+ Y + + E ++ + I+A D D Sbjct: 198 ---DRFPSDATVMTTFTILLIDKNDNAPKFNSSEYRLQITE-LAQVGFALPLFIQAEDKD 253 Query: 181 VGANSAIRYAIIGGNTQ-MQFSIDSLSG--DVSL--VKTLDYEQVRSYRLVIRAQDGGSP 235 G NS + + G N++ S ++ G D+ + LDYE +RSY + A + S Sbjct: 254 EGVNSMFQVFLTGNNSEYFTLSPTAVQGRADIRMRVAMPLDYEHIRSYSFSLYANESMS- 312 Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295 ++ I + + NDN P F L+ S+ EN G S++R+ A DAD G + Y Sbjct: 313 DHVGFARVFIELINENDNRPIFSKPLYNISLPENTAPGTSLLRILATDADAGTFGIVRYY 372 Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355 +D + D ++D +GWV LD E ++ L V A DGG T Sbjct: 373 FSD-----DPD-QFSLDEETGWVILQASLDYELMRRFTLTVLARDGGG--EETTGRIRVN 424 Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNT-RGRF 412 F Y L E+E PV L ATD D +N L Y I + F Sbjct: 425 VLDVNDNAPLFQKEAYVGSLRENEQAVQPVARLRATDEDSPPNNFLTYTIISASAFPSYF 484 Query: 413 SITSQNGRGLITVAQPLDFKQERRYV--LTVSATDSGGRS--DTAMVQINITDANNYAPV 468 SI G +I+V +PLD++Q + L V D G + T V + + D N+ P Sbjct: 485 SIIMVEGYAVISVTRPLDYEQVPSGMIHLEVMVKDGGSPALNSTVPVTVEVIDENDNPPE 544 Query: 469 FENAPYTASVFEDAPIG--TTVLVVSATDSDVGIN---AQITYSLSSEISNEAVAHHDQQ 523 F + Y + E+ G TVL+V+ATD D A + YSL Q Sbjct: 545 FSKSSYIVKIPENINAGEWATVLLVNATDLDASREFGQASLIYSLEGS----------SQ 594 Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT--TDVEISVVDVNDNEPVF 581 F +N ++G ITT LLDRE S Y+L V A DGGV T V I+++D+NDN PV+ Sbjct: 595 FRLNSRSGEITTTALLDRELKSEYILIVRAVDGGVGPQQKTGIATVNITILDINDNAPVW 654 Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641 + + Y AN++E + + T V V A D D G NG + Y + P E + I+ ++G IRT Sbjct: 655 RDEPYHANVVEMSPINTDVISVLALDPDNGENGTVVYSISP---ENPFYTINSSTGKIRT 711 Query: 642 NKA-LDRESVATHD---LKAV---AIDGGTPP--QSSTVIVHIKIEDINDSPPVFESDCL 692 + LDRES D ++ + A+D G+P S++ V + + D+ND+ P F + Sbjct: 712 SGVTLDRESSNPRDAILMRTIIISAVDRGSPQLRASASTTVFVNLLDLNDNDPKFLNLPF 771 Query: 693 TFYISENSPIGTTI 706 + E IG+++ Sbjct: 772 VAEVPEGLAIGSSV 785 Score = 218 bits (532), Expect = 2e-54 Identities = 199/668 (29%), Positives = 306/668 (45%), Gaps = 70/668 (10%) Query: 174 IKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233 + ATD D G ++ ++ + F+ID G V++ K LDYE +Y+L + A D Sbjct: 14 VNATDPDQGTGGSVLFSFQPPSPF--FAIDGARGTVTVTKPLDYETTSAYQLTVNATDQD 71 Query: 234 S-PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI----------------GYSI 276 S L I+I DV D P F + ++ E+VP+ GY + Sbjct: 72 KLRPLSRLANLAISITDVQDMDPIFTNLPYSTNIEEDVPLISQTQTHLGPLHTALQGYEV 131 Query: 277 VRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET---QAKYQ 333 ++ A D D G + YT+ +GN + +D SG + SGQLDRE A + Sbjct: 132 RKITAMDQDLGRPRGIGYTIV----SGNTNSVFALDYISGSLTVSGQLDRENPLYSAGFT 187 Query: 334 LLVTATDGGDP--PRSATA--TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV-VTL 388 L V AT+ + P AT T F +Y +++ E G + + + Sbjct: 188 LTVKATELKEDRFPSDATVMTTFTILLIDKNDNAPKFNSSEYRLQITELAQVGFALPLFI 247 Query: 389 TATDADEDNRLHYEI--TGGNTRG-RFSITSQNGRGLIT--VAQPLDFKQERRYVLTVSA 443 A D DE +++ TG N+ S T+ GR I VA PLD++ R Y ++ A Sbjct: 248 QAEDKDEGVNSMFQVFLTGNNSEYFTLSPTAVQGRADIRMRVAMPLDYEHIRSYSFSLYA 307 Query: 444 TDS-GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502 +S A V I + + N+ P+F Y S+ E+ GT++L + ATD+D G Sbjct: 308 NESMSDHVGFARVFIELINENDNRPIFSKPLYNISLPENTAPGTSLLRILATDADAGTFG 367 Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 + Y S + QF ++ +TG + LD E M + LTV ARDGG Sbjct: 368 IVRYYFSDD---------PDQFSLDEETGWVILQASLDYELMRRFTLTVLARDGG--GEE 416 Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP 622 T + ++V+DVNDN P+F+++ Y ++ E+ V+++ ATD D N + Y + Sbjct: 417 TTGRIRVNVLDVNDNAPLFQKEAYVGSLRENEQAVQPVARLRATDEDSPPNNFLTYTIIS 476 Query: 623 KDREEGSFVIDPASG--VIRTNKALDRESVATH--DLKAVAIDGGTPPQSSTVIVHIKIE 678 F I G VI + LD E V + L+ + DGG+P +STV V +++ Sbjct: 477 ASAFPSYFSIIMVEGYAVISVTRPLDYEQVPSGMIHLEVMVKDGGSPALNSTVPVTVEVI 536 Query: 679 DINDSPPVFESDCLTFYISENSPIG--TTIGEIRAHDPD---EGPNAVVHYSIKGGDDSN 733 D ND+PP F I EN G T+ + A D D E A + YS++G S+ Sbjct: 537 DENDNPPEFSKSSYIVKIPENINAGEWATVLLVNATDLDASREFGQASLIYSLEG---SS 593 Query: 734 SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR-----VEILVTDVN 788 F L +R G E+ T LD E + +Y L++RA + + V I + D+N Sbjct: 594 QFRLNSRSG----EITTTALLDREL-KSEYILIVRAVDGGVGPQQKTGIATVNITILDIN 648 Query: 789 DNAPVMKD 796 DNAPV +D Sbjct: 649 DNAPVWRD 656 Score = 201 bits (491), Expect = 2e-49 Identities = 240/899 (26%), Positives = 389/899 (43%), Gaps = 94/899 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTV-LTLKATDQDIGKNAEVEYTIELVTAD- 68 I ++D ND++P F +Y + E A G + L ++A D+D G N+ + + ++ Sbjct: 212 ILLIDKNDNAPKFNSSEYRLQITELAQVGFALPLFIQAEDKDEGVNSMFQVFLTGNNSEY 271 Query: 69 -TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 TL+P VQ R D R + LD E + Y+ + A + +S Sbjct: 272 FTLSP-----------TAVQG--RADIRMRVAMP---LDYEHIRSYSFSLYANES---MS 312 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 D + A + + +I++NDN P FS+ Y +S+ E+ + + + +I ATDAD G + Sbjct: 313 DHVGF-ARVFIELINENDNRPIFSKPLYNISLPENTAPGTS--LLRILATDADAGTFGIV 369 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 RY + QFS+D +G V L +LDYE +R + L + A+DGG T ++ +N+ Sbjct: 370 RYYF--SDDPDQFSLDEETGWVILQASLDYELMRRFTLTVLARDGGG--EETTGRIRVNV 425 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 DVNDNAP F + S+ EN + R++A D D N LTYT+ + Sbjct: 426 LDVNDNAPLFQKEAYVGSLRENEQAVQPVARLRATDEDSPPNNFLTYTIISASAFPSYFS 485 Query: 308 PITIDPRSGWVYTSGQLDRET--QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 I ++ + + + LD E L V DGG P ++T Sbjct: 486 IIMVEGYAV-ISVTRPLDYEQVPSGMIHLEVMVKDGGSPALNSTVPVTVEVIDENDNPPE 544 Query: 366 FMPGQYEVELAEDEPPG--TPVVTLTATDADEDNR-----LHYEITGGNTRGRFSITSQN 418 F Y V++ E+ G V+ + ATD D L Y + G + +F + S++ Sbjct: 545 FSKSSYIVKIPENINAGEWATVLLVNATDLDASREFGQASLIYSLEGSS---QFRLNSRS 601 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTA 476 G IT LD + + Y+L V A D G + T + +NIT + + +NAP Sbjct: 602 GE--ITTTALLDRELKSEYILIVRAVDGGVGPQQKTGIATVNITILD----INDNAP--- 652 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 V+ D P V+ +S IN + L+ + N + + I+P+ T N Sbjct: 653 -VWRDEPYHANVVEMSP------INTDVISVLALDPDNGE--NGTVVYSISPENPFYTIN 703 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 + SG L + + L T + IS VD P + T V Sbjct: 704 SSTGKIRTSGVTLDRESSNPRDAILMRT--IIISAVD--RGSPQLRASASTT-------V 752 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 ++ + D LN E+ P+ GS V S ++ A E + + L+ Sbjct: 753 FVNLLDLNDNDPKF-LNLPFVAEV-PEGLAIGSSVFKAFSPPPQSWTA---EQIGLYYLR 807 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 +A D G P++ST + +K+ D+ND P F+ + E+ P + + D D Sbjct: 808 IIAYDAGNFPRTSTSTLTVKVLDVNDETPTFDPRVYNVSLKESIPRDHVVARLACSDNDA 867 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA-----AS 771 G NA + Y I GG+ FS+ R G + T+V LD E+ + Y L++ A A Sbjct: 868 GLNAELSYFITGGNQDGKFSVGFRDGIVR----TVVGLDRET-QAAYTLIVEAIDNGPAG 922 Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTD--KLQ 828 V + V DVNDN P+ + + P G +V A DAD + + Sbjct: 923 SRRTGTATVFVEVQDVNDNRPIFLQ-NSYETSVLESVPQGTSILQVQATDADQGENGSVL 981 Query: 829 YRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887 YRIL+GN+ NL ++ TG +T L + ++ + + N + M+ SVR+I Sbjct: 982 YRILTGNSNNLFSIDRQTGLVTRG--LRALDRETSSSHMLEVEAYNSDEGSMRSSVRVI 1038 Score = 154 bits (373), Expect = 4e-35 Identities = 118/348 (33%), Positives = 170/348 (48%), Gaps = 32/348 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + +L+ D + F YEAS+RE ++GT V+ ++A D ++ Y + Sbjct: 1124 VTLLNELDEAVAFSSAGYEASLRENIATGTEVIQVQAQSAD--NLNQLTYRFD------- 1174 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD----QASPV 126 P+ + +F+ID +G + LDRE+ YT+ V A D + S V Sbjct: 1175 -PDTSPAALA--------LFKIDSVTGRITVTGLLDRERGDAYTLTVVADDGGPKKDSTV 1225 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 S + + + I+D+NDN P F + T SVD + +A + A D D G N Sbjct: 1226 ITSDSISQQVSITILDENDNSPVF-DITSDTSVDITENTPMGEKVAVVLARDKDAGLNGL 1284 Query: 187 IRYAIIGGNTQMQFSIDSLS---GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 I + ++ GN + F I +++ G+V + LD E V Y L +RA D GSP R L Sbjct: 1285 INFTLVAGNMKDVFKIKTVNHTYGEVYVNAPLDRESVDRYLLKVRATDNGSPPRHTDHSL 1344 Query: 244 LINIRDVNDNAPRFYTSL-FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 INI DVNDNAP + + S+SENV G S++RV A D D G NA L Y +T Sbjct: 1345 TINILDVNDNAPVIESQKGYNVSISENVGGGTSVLRVMATDRDIGPNAMLFYYIT----A 1400 Query: 303 GNVDLPITIDPRSGWVYT-SGQLDRETQAKYQLLVTATDGGDPPRSAT 349 GN DL +D +G + T DRE Q +Y L VT D G PP S + Sbjct: 1401 GNQDLTFRMDRMTGEMVTRPAPPDRERQQEYILTVTVEDDGTPPLSVS 1448 Score = 149 bits (360), Expect = 1e-33 Identities = 170/649 (26%), Positives = 262/649 (40%), Gaps = 64/649 (9%) Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325 + +N P+G S+ V A D D+G + ++ ID G V + LD Sbjct: 1 ILQNTPVGRSVFMVNATDPDQGTGGSVLFSFQPPSPF------FAIDGARGTVTVTKPLD 54 Query: 326 RETQAKYQLLVTATDGGD-PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP---- 380 ET + YQL V ATD P S A F Y + ED P Sbjct: 55 YETTSAYQLTVNATDQDKLRPLSRLANLAISITDVQDMDPIFTNLPYSTNIEEDVPLISQ 114 Query: 381 ------------PGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 G V +TA D D + Y I GNT F++ +G +TV+ Sbjct: 115 TQTHLGPLHTALQGYEVRKITAMDQDLGRPRGIGYTIVSGNTNSVFALDYISGS--LTVS 172 Query: 427 QPLDFKQ---ERRYVLTVSAT----DSGGRSDTAMVQINI--TDANNYAPVFENAPYTAS 477 LD + + LTV AT D T M I D N+ AP F ++ Y Sbjct: 173 GQLDRENPLYSAGFTLTVKATELKEDRFPSDATVMTTFTILLIDKNDNAPKFNSSEYRLQ 232 Query: 478 VFEDAPIGTTV-LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 + E A +G + L + A D D G+N+ L+ +N V + Sbjct: 233 ITELAQVGFALPLFIQAEDKDEGVNSMFQVFLTG--NNSEYFTLSPTAVQGRADIRMRVA 290 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTD---VEISVVDVNDNEPVFKQQLYTANIMED 593 LD E + Y ++ A + S+SD V I +++ NDN P+F + LY ++ E+ Sbjct: 291 MPLDYEHIRSYSFSLYANE----SMSDHVGFARVFIELINENDNRPIFSKPLYNISLPEN 346 Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653 GTS+ ++ ATDAD G G + Y + F +D +G + +LD E + Sbjct: 347 TAPGTSLLRILATDADAGTFGIVRYYFSD---DPDQFSLDEETGWVILQASLDYELMRRF 403 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713 L +A DGG + +T + + + D+ND+ P+F+ + + EN + +RA D Sbjct: 404 TLTVLARDGG--GEETTGRIRVNVLDVNDNAPLFQKEAYVGSLRENEQAVQPVARLRATD 461 Query: 714 PDEGPNAVVHYSIKGGDDSNS-FSLETRQGSDKAELVTMVDLDYE---SPRKKYELVIR- 768 D PN + Y+I S FS+ +G A + LDYE S E++++ Sbjct: 462 EDSPPNNFLTYTIISASAFPSYFSIIMVEG--YAVISVTRPLDYEQVPSGMIHLEVMVKD 519 Query: 769 AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR---VPAYDADVTD 825 SP L + V V + V D NDN P I + G + V A D D + Sbjct: 520 GGSPALNSTVPVTVEVIDENDNPPEFSKSSYIV-KIPENINAGEWATVLLVNATDLDASR 578 Query: 826 KLQYR--ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 + I S ++ LN +G +T + L+ + + V DG Sbjct: 579 EFGQASLIYSLEGSSQFRLNSRSGEITTTALLDRELKSEYILIVRAVDG 627 Score = 141 bits (341), Expect = 3e-31 Identities = 106/353 (30%), Positives = 170/353 (48%), Gaps = 36/353 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++NVLD ND++P+F+ + Y S+RE + V L+ATD+D N + YTI +A Sbjct: 422 RVNVLDVNDNAPLFQKEAYVGSLRENEQAVQPVARLRATDEDSPPNNFLTYTIISASA-- 479 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKV--ARYTVLVKATDQASPVS 127 + ++G + +TR LD E+V + V D SP Sbjct: 480 -------------FPSYFSIIMVEGYAVISVTR-PLDYEQVPSGMIHLEVMVKDGGSPA- 524 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 L+ST + V +ID+NDN P+FS+ +Y V + E+I+ + + + ATD D Sbjct: 525 --LNSTVPVTVEVIDENDNPPEFSKSSYIVKIPENINAGEWATVLLVNATDLDASREFGQ 582 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 I QF ++S SG+++ LD E Y L++RA DGG + T +NI Sbjct: 583 ASLIYSLEGSSQFRLNSRSGEITTTALLDRELKSEYILIVRAVDGGVGPQQKTGIATVNI 642 Query: 248 R--DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 D+NDNAP + + +V E PI ++ V A D D G N + Y+++ ++ Sbjct: 643 TILDINDNAPVWRDEPYHANVVEMSPINTDVISVLALDPDNGENGTVVYSISPENPF--- 699 Query: 306 DLPITIDPRSGWVYTSG-QLDRETQ------AKYQLLVTATDGGDPPRSATAT 351 TI+ +G + TSG LDRE+ ++++A D G P A+A+ Sbjct: 700 ---YTINSSTGKIRTSGVTLDRESSNPRDAILMRTIIISAVDRGSPQLRASAS 749 Score = 117 bits (282), Expect = 4e-24 Identities = 118/426 (27%), Positives = 181/426 (42%), Gaps = 39/426 (9%) Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 + ++ P+G +V +V+ATD D G + +S F I+ G +T K Sbjct: 1 ILQNTPVGRSVFMVNATDPDQGTGGSVLFSFQPP---------SPFFAIDGARGTVTVTK 51 Query: 538 LLDRETMSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED--- 593 LD ET S Y LTV A D + LS ++ IS+ DV D +P+F Y+ NI ED Sbjct: 52 PLDYETTSAYQLTVNATDQDKLRPLSRLANLAISITDVQDMDPIFTNLPYSTNIEEDVPL 111 Query: 594 -------------ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640 AL G V ++ A D D+G I Y + F +D SG + Sbjct: 112 ISQTQTHLGPLHTALQGYEVRKITAMDQDLGRPRGIGYTI-VSGNTNSVFALDYISGSLT 170 Query: 641 TNKALDRESVA-----THDLKAVAIDGGTPPQSSTVIV--HIKIEDINDSPPVFESDCLT 693 + LDRE+ T +KA + P +TV+ I + D ND+ P F S Sbjct: 171 VSGQLDRENPLYSAGFTLTVKATELKEDRFPSDATVMTTFTILLIDKNDNAPKFNSSEYR 230 Query: 694 FYISENSPIGTTIG-EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR--QGSDKAELVT 750 I+E + +G + I+A D DEG N++ + G++S F+L QG + Sbjct: 231 LQITELAQVGFALPLFIQAEDKDEGVNSMFQVFLT-GNNSEYFTLSPTAVQGRADIRMRV 289 Query: 751 MVDLDYESPRK-KYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809 + LDYE R + L + RV I + + NDN P+ + ++ P Sbjct: 290 AMPLDYEHIRSYSFSLYANESMSDHVGFARVFIELINENDNRPIFSKPLYNISLPENTAP 349 Query: 810 VGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSV 869 R+ A DAD R ++ + L+E TG + L L+ + + T+ V Sbjct: 350 GTSLLRILATDADAGTFGIVRYYFSDDPDQFSLDEETGWVILQASLDYELMRRFTLTVLA 409 Query: 870 TDGVNE 875 DG E Sbjct: 410 RDGGGE 415 >UniRef50_Q4RPF4 Cluster: Chromosome 1 SCAF15008, whole genome shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 1 SCAF15008, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1210 Score = 278 bits (681), Expect = 2e-72 Identities = 197/624 (31%), Positives = 306/624 (49%), Gaps = 38/624 (6%) Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISV-TDNPVIAKIKATDAD 180 + + + D + I I D NDN P F +S+ E+ ++ T PV + A D D Sbjct: 81 EVAVLPDEIFRLVKIRFLIEDVNDNAPLFQSTVINISIPENTAINTRYPVPS---AFDPD 137 Query: 181 VGANSAIRYAIIGGNTQMQFSI-DSLSGD----VSLVKTLDYEQVRSYRLVIRAQDGGSP 235 VG N Y ++ ++ I ++ GD + + + LD EQ +Y + I+ +DGG+P Sbjct: 138 VGINGIQHYELVKSVSEFGLDIIETPEGDKWPQLIVQQNLDREQKDTYVMKIKVEDGGNP 197 Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295 +S+T L + I DVNDN P F S + +V EN P+G S+ ++ A DAD G NA++ +T Sbjct: 198 PKSSTAILQVTISDVNDNRPIFKDSELEVTVPENAPMGTSVAQLHATDADLGSNAQIHFT 257 Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT----AT 351 +++ G +ID +G + LDRE ++L+V A+DG P AT T Sbjct: 258 FSNQISAG-TKRHFSIDGSTGLITVKQSLDRELTPVHKLIVLASDGSSTPSRATVIVNVT 316 Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEI---TGGNT 408 V L+E+ P T + +T TD D D L+ ++ T + Sbjct: 317 DVNDNVPTIDTRYIINLVNGTVLLSENAPLNTKIALITVTDKDAD--LYGKVACYTDHDV 374 Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYA 466 R N + L+ A PLD++ R Y + + A+D G + +AMV I I D N+ Sbjct: 375 PFRLKPVF-NDQFLLETAAPLDYETTREYAIKIVASDRGTPPLNTSAMVLIKIKDENDNV 433 Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 P+F S+ E+ T ++ +SATD+D NA+I Y+L + + F + Sbjct: 434 PIFPQPEIQLSIPENNDPSTQLIKLSATDADSEHNAEIIYTLGPDA--------PEGFNV 485 Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586 + ++G ++ K LDRE Y TV A+D G SL V++ V D+NDN P F Y Sbjct: 486 DRRSGVLSVGKRLDREKQDRYAFTVIAKDNGSTSLQSNVTVKLIVQDLNDNSPAFTHPEY 545 Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGVIRTNKAL 645 + E+ + +V + TDAD G N + L+ KD +F+IDP +GVI+ N Sbjct: 546 NFYVPENLPLFGTVGLITVTDADSGENAVVTLSILNGKD----NFIIDPQTGVIKPNITF 601 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF---ESDCLTFYISENSPI 702 DRE +++ A+DGG PP SS V I + D+ND+ PVF S+ + N+ Sbjct: 602 DREQQSSYTFMVKAVDGGQPPSSSYAKVTINVVDVNDNRPVFVIPSSNYSYDLVRTNASP 661 Query: 703 GTTIGEIRAHDPDEGPNAVVHYSI 726 G + + A D D G NA + YSI Sbjct: 662 GAVVTRVYAIDNDTGMNAELQYSI 685 Score = 262 bits (643), Expect = 7e-68 Identities = 205/688 (29%), Positives = 329/688 (47%), Gaps = 60/688 (8%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 D ND++P+F+ S+ E + T A D D+G N Y ELV + + D Sbjct: 101 DVNDNAPLFQSTVINISIPENTAINTRYPVPSAFDPDVGINGIQHY--ELVKSVSEFGLD 158 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTA 134 + L+ + +LDRE+ Y + +K D +P SSTA Sbjct: 159 IIETPEGD------------KWPQLIVQQNLDREQKDTYVMKIKVEDGGNPPK---SSTA 203 Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI--- 191 + V I D NDN P F + V+V E+ + + +A++ ATDAD+G+N+ I + Sbjct: 204 ILQVTISDVNDNRPIFKDSELEVTVPENAPMGTS--VAQLHATDADLGSNAQIHFTFSNQ 261 Query: 192 IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS-PSRSNTTQLLINIRDV 250 I T+ FSID +G +++ ++LD E ++L++ A DG S PSR+ +++N+ DV Sbjct: 262 ISAGTKRHFSIDGSTGLITVKQSLDRELTPVHKLIVLASDGSSTPSRAT---VIVNVTDV 318 Query: 251 NDNAP----RFYTSLFQESV--SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 NDN P R+ +L +V SEN P+ I + D D + ++ TD D Sbjct: 319 NDNVPTIDTRYIINLVNGTVLLSENAPLNTKIALITVTDKDADLYGKVA-CYTDHDVPFR 377 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 + P+ D + T+ LD ET +Y + + A+D G PP + +A Sbjct: 378 LK-PVFND--QFLLETAAPLDYETTREYAIKIVASDRGTPPLNTSAMVLIKIKDENDNVP 434 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT-GGNTRGRFSITSQNGRGLI 423 F + ++ + E+ P T ++ L+ATDAD ++ T G + F++ ++ G++ Sbjct: 435 IFPQPEIQLSIPENNDPSTQLIKLSATDADSEHNAEIIYTLGPDAPEGFNVDRRS--GVL 492 Query: 424 TVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFED 481 +V + LD +++ RY TV A D+G S V++ + D N+ +P F + Y V E+ Sbjct: 493 SVGKRLDREKQDRYAFTVIAKDNGSTSLQSNVTVKLIVQDLNDNSPAFTHPEYNFYVPEN 552 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 P+ TV +++ TD+D G NA +T S+ + N F+I+PQTG I N DR Sbjct: 553 LPLFGTVGLITVTDADSGENAVVTLSILNGKDN---------FIIDPQTGVIKPNITFDR 603 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF--KQQLYTANIME-DALVGT 598 E S Y V A DGG P S V I+VVDVNDN PVF Y+ +++ +A G Sbjct: 604 EQQSSYTFMVKAVDGGQPPSSSYAKVTINVVDVNDNRPVFVIPSSNYSYDLVRTNASPGA 663 Query: 599 SVSQVGATDADVGLNGRIHYE------LDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652 V++V A D D G+N + Y + + G F ID ++G I + + Sbjct: 664 VVTRVYAIDNDTGMNAELQYSIISSIIITSRVSPRGLFAIDKSTGNITLQEKIVAADQGL 723 Query: 653 HDLKAVAIDGGTPPQSSTV-IVHIKIED 679 H L D G P + +VH+ + D Sbjct: 724 HRLVVKVRDLGQPESLHAITLVHLFVND 751 Score = 258 bits (633), Expect = 1e-66 Identities = 207/682 (30%), Positives = 308/682 (45%), Gaps = 49/682 (7%) Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 I DVNDNAP F +++ S+ EN I A+D D G+N Y + +D Sbjct: 99 IEDVNDNAPLFQSTVINISIPENTAINTRYPVPSAFDPDVGINGIQHYELVKSVSEFGLD 158 Query: 307 LPITIDPRSGW--VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 + I W + LDRE + Y + + DGG+PP+S+TA Sbjct: 159 I-IETPEGDKWPQLIVQQNLDREQKDTYVMKIKVEDGGNPPKSSTAILQVTISDVNDNRP 217 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITG---GNTRGRFSITSQNG 419 F + EV + E+ P GT V L ATDAD + ++H+ + T+ FSI G Sbjct: 218 IFKDSELEVTVPENAPMGTSVAQLHATDADLGSNAQIHFTFSNQISAGTKRHFSIDGSTG 277 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPY----- 474 LITV Q LD + + L V A+D A V +N+TD N+ P + Sbjct: 278 --LITVKQSLDRELTPVHKLIVLASDGSSTPSRATVIVNVTDVNDNVPTIDTRYIINLVN 335 Query: 475 -TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 T + E+AP+ T + +++ TD D + ++ ++ + QF++ Sbjct: 336 GTVLLSENAPLNTKIALITVTDKDADLYGKVACYTDHDVPFRLKPVFNDQFLLE------ 389 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593 T LD ET Y + + A D G P L+ + V I + D NDN P+F Q +I E+ Sbjct: 390 -TAAPLDYETTREYAIKIVASDRGTPPLNTSAMVLIKIKDENDNVPIFPQPEIQLSIPEN 448 Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653 T + ++ ATDAD N I Y L P D EG F +D SGV+ K LDRE + Sbjct: 449 NDPSTQLIKLSATDADSEHNAEIIYTLGP-DAPEG-FNVDRRSGVLSVGKRLDREKQDRY 506 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713 +A D G+ S V V + ++D+ND+ P F FY+ EN P+ T+G I D Sbjct: 507 AFTVIAKDNGSTSLQSNVTVKLIVQDLNDNSPAFTHPEYNFYVPENLPLFGTVGLITVTD 566 Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP 773 D G NAVV SI G D +F ++ + G K + D + +S + PP Sbjct: 567 ADSGENAVVTLSILNGKD--NFIIDPQTGVIKPNIT--FDREQQSSYTFMVKAVDGGQPP 622 Query: 774 LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYK------DCFPVGPFGRVPAYDAD--VTD 825 + +V I V DVNDN PV F I +NY + P RV A D D + Sbjct: 623 SSSYAKVTINVVDVNDNRPV---FVIPSSNYSYDLVRTNASPGAVVTRVYAIDNDTGMNA 679 Query: 826 KLQYRILSG-------NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIK 877 +LQY I+S + L ++++TG++TL ++ L + V V D G E Sbjct: 680 ELQYSIISSIIITSRVSPRGLFAIDKSTGNITLQEKIVAADQGLHRLVVKVRDLGQPESL 739 Query: 878 AMMQLSVRLITEEMLLNSITVR 899 + L V L + + NS ++ Sbjct: 740 HAITL-VHLFVNDTVSNSTFIQ 760 Score = 217 bits (530), Expect = 4e-54 Identities = 180/590 (30%), Positives = 266/590 (45%), Gaps = 46/590 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI-ELVTAD 68 Q+ + D ND+ P+F+ + E +V E A GT+V L ATD D+G NA++ +T ++A Sbjct: 206 QVTISDVNDNRPIFKDSELEVTVPENAPMGTSVAQLHATDADLGSNAQIHFTFSNQISAG 265 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 T + F IDG +G + + SLDRE + ++V A+D +S Sbjct: 266 T-----------------KRHFSIDGSTGLITVKQSLDRELTPVHKLIVLASDGSS---- 304 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDN-PV---IAKIKATDADVGAN 184 S AT+ VN+ D NDN P + V+ + +++N P+ IA I TD D Sbjct: 305 -TPSRATVIVNVTDVNDNVPTIDTRYIINLVNGTVLLSENAPLNTKIALITVTDKDADLY 363 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRSNTT 241 + + + F + + D L++T LDYE R Y + I A D G+P + + Sbjct: 364 GKVACYT---DHDVPFRLKPVFNDQFLLETAAPLDYETTREYAIKIVASDRGTPPLNTSA 420 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 +LI I+D NDN P F Q S+ EN ++++ A DAD NAE+ YT+ Sbjct: 421 MVLIKIKDENDNVPIFPQPEIQLSIPENNDPSTQLIKLSATDADSEHNAEIIYTLGPDAP 480 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 G +D RSG + +LDRE Q +Y V A D G + T Sbjct: 481 EG-----FNVDRRSGVLSVGKRLDREKQDRYAFTVIAKDNGSTSLQSNVTVKLIVQDLND 535 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421 F +Y + E+ P V +T TDAD ++ N + F I Q G Sbjct: 536 NSPAFTHPEYNFYVPENLPLFGTVGLITVTDADSGENAVVTLSILNGKDNFIIDPQT--G 593 Query: 422 LITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVF--ENAPYTAS 477 +I D +Q+ Y V A D G S A V IN+ D N+ PVF ++ Y+ Sbjct: 594 VIKPNITFDREQQSSYTFMVKAVDGGQPPSSSYAKVTINVVDVNDNRPVFVIPSSNYSYD 653 Query: 478 -VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 V +A G V V A D+D G+NA++ YS+ S I + F I+ TG IT Sbjct: 654 LVRTNASPGAVVTRVYAIDNDTGMNAELQYSIISSIIITSRVSPRGLFAIDKSTGNITLQ 713 Query: 537 KLLDRETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQL 585 + + + L V RD G P SL T V + V D N ++QL Sbjct: 714 EKIVAADQGLHRLVVKVRDLGQPESLHAITLVHLFVNDTVSNSTFIQEQL 763 Score = 169 bits (412), Expect = 7e-40 Identities = 133/454 (29%), Positives = 218/454 (48%), Gaps = 24/454 (5%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 ++ I D N+ AP+F++ S+ E+ I T V SA D DVGIN Y L +S Sbjct: 95 IRFLIEDVNDNAPLFQSTVINISIPENTAINTRYPVPSAFDPDVGINGIQHYELVKSVSE 154 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 + + + + + LDRE Y++ + DGG P S T +++++ DV Sbjct: 155 FGLDIIETPE--GDKWPQLIVQQNLDREQKDTYVMKIKVEDGGNPPKSSTAILQVTISDV 212 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK--DREEGSFVI 632 NDN P+FK + E+A +GTSV+Q+ ATDAD+G N +IH+ + + F I Sbjct: 213 NDNRPIFKDSELEVTVPENAPMGTSVAQLHATDADLGSNAQIHFTFSNQISAGTKRHFSI 272 Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692 D ++G+I ++LDRE H L +A DG + P +TVIV+ + D+ND+ P ++ + Sbjct: 273 DGSTGLITVKQSLDRELTPVHKLIVLASDGSSTPSRATVIVN--VTDVNDNVPTIDTRYI 330 Query: 693 ------TFYISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745 T +SEN+P+ T I I D D + V Y+ D F L+ +D+ Sbjct: 331 INLVNGTVLLSENAPLNTKIALITVTDKDADLYGKVACYT----DHDVPFRLKP-VFNDQ 385 Query: 746 AELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN 802 L T LDYE+ R +Y + I A+ +PPL V I + D NDN P+ +I + Sbjct: 386 FLLETAAPLDYETTR-EYAIKIVASDRGTPPLNTSAMVLIKIKDENDNVPIFPQPEIQLS 444 Query: 803 NYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNA-NLILLNETTGSMTLSPQLNTNVPK 861 ++ P ++ A DAD + G +A ++ +G +++ +L+ Sbjct: 445 IPENNDPSTQLIKLSATDADSEHNAEIIYTLGPDAPEGFNVDRRSGVLSVGKRLDREKQD 504 Query: 862 LATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNS 895 V D ++V+LI +++ NS Sbjct: 505 RYAFTVIAKDN-GSTSLQSNVTVKLIVQDLNDNS 537 >UniRef50_Q4T0W6 Cluster: Chromosome 1 SCAF10821, whole genome shotgun sequence; n=41; Clupeocephala|Rep: Chromosome 1 SCAF10821, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1151 Score = 277 bits (680), Expect = 2e-72 Identities = 269/972 (27%), Positives = 428/972 (44%), Gaps = 90/972 (9%) Query: 4 PFCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 P +H+ I+V D ND+SP F+ + + +RE A G L +A D DIG+N YT+ Sbjct: 109 PLELHRISIHVQDINDNSPQFKEESIKLEIRESAVKGARFLLGEAHDADIGQNTVQGYTL 168 Query: 63 ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122 + LN + + LL LDRE +L+ A D Sbjct: 169 QQNDHFKLNVNTKSS---------------NRKYCELLLDKELDREDKQELQLLLTAVDG 213 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 SP + S T IHV ++D NDN P FS+ Y S+ E+ S D VI + A DAD G Sbjct: 214 GSP---QRSGTVVIHVTVLDANDNAPVFSQSVYKTSLPEN-SPLDTLVIT-VSAADADEG 268 Query: 183 ANSAIRYAIIGG-NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 NS I Y + F +D+ +G V + +DYE++ SY + I A+DG T Sbjct: 269 VNSEITYGFDHVLEDENVFLLDTKTGVVRVNGAIDYEKIPSYEMQISAKDGLGLVAYAT- 327 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 L+I I DVNDNAP + + ENV G + + D D N ++ ++ Sbjct: 328 -LIIEITDVNDNAPVIHLKSLTNPIPENVSPGSEVGIINVQDRDSENNRQVRCSIQQ--- 383 Query: 302 TGNVDLPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 NV + ++ + + T+GQLDRE + Y + ++ATD G PP S++ + Sbjct: 384 --NVPFKLVASIKNYYSLVTTGQLDRELVSDYNITISATDEGSPPLSSSKSVHLSVADVN 441 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGR--FSITS 416 F Y ++E+ G+ + +++A D D ++ + Y + G S S Sbjct: 442 DNPPVFEEQSYSAYVSENNRAGSTLCSVSARDPDWRQNGTVIYSLLAAEVSGAPVSSYVS 501 Query: 417 QNG-RGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAP-VFENA 472 NG G+I + D++Q R + + V A D+G S V + ++D N+ P + A Sbjct: 502 VNGDTGVIHAVRSFDYEQLRSFKVHVMARDNGSPPLSSNVSVSVFVSDVNDNPPQILYPA 561 Query: 473 P-----YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527 P T V + A G+ V V A D+D G NA ++Y + S+ + F I Sbjct: 562 PEGNSFMTELVPKAAHGGSLVSKVIAVDADSGQNAWLSYHIVQS-SDPGL------FTIG 614 Query: 528 PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY- 586 +G I T + + L V +D G PSLS T + + + D P K Y Sbjct: 615 VHSGEIRTQRDISESDSMKQNLIVAVKDNGQPSLSATCSMYLLISDNLAEVPELKDISYE 674 Query: 587 --TANIMEDALVG-TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA-------- 635 + + ++ VS T + L R P+ +G+ I A Sbjct: 675 EKNSKLTSYLIIALVCVSTFFLTFIIIILGVRFCRRRKPRMLFDGAVTIPGAYLPPNYAD 734 Query: 636 ---SGVIR---------TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS 683 +G +R T LDRE V+ +++ A D G+PP SS+ VH+ + D+ND+ Sbjct: 735 VDGTGTLRSAYNYDAYLTTGQLDRELVSDYNITISATDEGSPPLSSSKSVHLSVADVNDN 794 Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS-FSLETRQG 742 PPVFE + Y+ EN+ G+T+ + A DPD N V YS+ + S + S Sbjct: 795 PPVFEEQSYSAYVRENNRAGSTLCSVSARDPDWRQNGTVIYSLLAAEVSGAPVSSYVSVN 854 Query: 743 SDKAELVTMVDLDYESPRK-KYELVIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQII 800 D + + DYE R K ++ R SPPL ++V V + V+DVNDN P + Sbjct: 855 GDTGVIHAVRSFDYEQLRSFKVHVMARDNGSPPLSSNVSVSVFVSDVNDNPPQILYPAPE 914 Query: 801 FNNY-KDCFPVGPFG-----RVPAYDADVTDK--LQYRILSGNNANLILLNETTGSMTLS 852 N++ + P G +V A DAD L Y I+ ++ L + +G + Sbjct: 915 GNSFMTELVPKAAHGGSLVSKVIAVDADSGQNAWLSYHIVQSSDPGLFTIGVHSGEIRTQ 974 Query: 853 PQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSP 911 ++ + + V+V D G + A + + LI++ + + L D++ E+ S Sbjct: 975 RDISESDSMKQNLIVAVKDNGQPSLSATCSMYL-LISDNL---AEVPELKDISYEEKNSK 1030 Query: 912 LLGFFIDGLAAI 923 L + I L + Sbjct: 1031 LTSYLIIALVCV 1042 Score = 234 bits (573), Expect = 2e-59 Identities = 180/599 (30%), Positives = 277/599 (46%), Gaps = 30/599 (5%) Query: 96 SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155 +G L+ + +DRE + + V + I +++ D NDN PQF E++ Sbjct: 77 TGELIVQERIDREALCEKKASCVLKQEL--VLENPLELHRISIHVQDINDNSPQFKEESI 134 Query: 156 TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG-----DVS 210 + + E S +A DAD+G N+ Y + N + ++++ S ++ Sbjct: 135 KLEIRE--SAVKGARFLLGEAHDADIGQNTVQGYTL-QQNDHFKLNVNTKSSNRKYCELL 191 Query: 211 LVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENV 270 L K LD E + +L++ A DGGSP RS T + + + D NDNAP F S+++ S+ EN Sbjct: 192 LDKELDREDKQELQLLLTAVDGGSPQRSGTVVIHVTVLDANDNAPVFSQSVYKTSLPENS 251 Query: 271 PIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA 330 P+ ++ V A DADEGVN+E+TY NV L +D ++G V +G +D E Sbjct: 252 PLDTLVITVSAADADEGVNSEITYGFDHVLEDENVFL---LDTKTGVVRVNGAIDYEKIP 308 Query: 331 KYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTA 390 Y++ ++A DG A AT + E+ PG+ V + Sbjct: 309 SYEMQISAKDG--LGLVAYATLIIEITDVNDNAPVIHLKSLTNPIPENVSPGSEVGIINV 366 Query: 391 TDADEDNRLHYEIT-GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG- 448 D D +N + N + + +N L+T Q LD + Y +T+SATD G Sbjct: 367 QDRDSENNRQVRCSIQQNVPFKLVASIKNYYSLVTTGQ-LDRELVSDYNITISATDEGSP 425 Query: 449 -RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507 S + V +++ D N+ PVFE Y+A V E+ G+T+ VSA D D N + YS Sbjct: 426 PLSSSKSVHLSVADVNDNPPVFEEQSYSAYVSENNRAGSTLCSVSARDPDWRQNGTVIYS 485 Query: 508 -LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566 L++E+S V+ + +N TG I + D E + + + V ARD G P LS Sbjct: 486 LLAAEVSGAPVSSY---VSVNGDTGVIHAVRSFDYEQLRSFKVHVMARDNGSPPLSSNVS 542 Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALV------GTSVSQVGATDADVGLNGRIHYEL 620 V + V DVNDN P N LV G+ VS+V A DAD G N + Y + Sbjct: 543 VSVFVSDVNDNPPQILYPAPEGNSFMTELVPKAAHGGSLVSKVIAVDADSGQNAWLSYHI 602 Query: 621 DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679 + + G F I SG IRT + + +L D G P S+T +++ I D Sbjct: 603 -VQSSDPGLFTIGVHSGEIRTQRDISESDSMKQNLIVAVKDNGQPSLSATCSMYLLISD 660 >UniRef50_Q4SFY8 Cluster: Chromosome 7 SCAF14601, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 7 SCAF14601, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 2270 Score = 277 bits (680), Expect = 2e-72 Identities = 234/757 (30%), Positives = 358/757 (47%), Gaps = 104/757 (13%) Query: 11 INVLDCNDHSPVFEMQQYEAS----VREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 I VLD ND++P F + + V EG SGT + T+ A D D G+N V Y++ Sbjct: 670 ITVLDENDNAPTFSHTRPDRELLLQVVEGLPSGTVLGTVTAKDPDEGENGTVHYSLSGAR 729 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 A+ F ++ +G L + L + + YT +V A D SP Sbjct: 730 AER--------------------FTLNPMTGELKAASPLRWAERSEYTFMVTAADHGSP- 768 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 LSST + + ++ + ++V+++ +I +++ + +++ Sbjct: 769 --GLSSTCRLQIQVLSSARS--NLKPNIFSVTMNAVEGAPPGSIIGSVRSQNHQQSSSTE 824 Query: 187 --IRYAIIGGNTQM-QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS--PSRSNTT 241 + Y ++GG+ + F +D L GDV LV+ LDYE+ Y L I D PS S+ Sbjct: 825 GQVTYLVVGGSDRDGTFMVDRLKGDVYLVRELDYEKGSRYTLHIEVSDFSQAFPS-SHLV 883 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKD 300 QL IN++D ND+AP F + EN G S+ QA D D G N+EL Y++ + Sbjct: 884 QLEINVQDRNDHAPHFTEDPVTIVIPENTEPGASVYTFQAIDKDGSGPNSELIYSI--EH 941 Query: 301 YTGNVDLPITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATDGGDPP---RSATATXXXXX 356 Y L +++DP SG V T GQ LDRE+ L+V ATD P R + T Sbjct: 942 YWPETHL-LSLDPVSG-VLTLGQKLDRESTPSLFLVVRATDQTVDPSQRRWGSVTARMFV 999 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSI 414 F V + ED+P G ++ + A D DE + R+ Y I GNT GRFS+ Sbjct: 1000 TDENDNTPVFSSPS-AVSVMEDQPVGFVILYVMARDEDEGENGRVSYRIQAGNTAGRFSL 1058 Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENA 472 G +++ + LD +++ + LT+ A D G S + ++ + + D N+ APVF+ A Sbjct: 1059 NPNTGS--LSILKALDREEQEVFNLTIVAEDHGIPQLSTSQVLSVRVIDVNDEAPVFQRA 1116 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITY-----------------SLSSEISNE 515 + A V E+ GTTVL V+A D D G N +TY + + E+ E Sbjct: 1117 EFEALVIENKGPGTTVLKVTAVDRDQGSNGHVTYGGVTEEGFVINPVTGVITTTKELDTE 1176 Query: 516 AVAHH-------DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568 A H+ D F ++P TGA++T++ LDRET + Y L V A D G P+LS T V+ Sbjct: 1177 AQDHYTLTAGDPDGDFHLHPSTGALSTSRGLDRETKAEYTLEVVASDRGSPALSTTVMVQ 1236 Query: 569 ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG 628 + V+DVNDN P+F +AD LNG+ Y L G Sbjct: 1237 VQVMDVNDNSPIF-------------------------NADDALNGKFLYFLSQD--AHG 1269 Query: 629 SFVIDPASGVIRTNKALDRESVATHDLKAVAID-GGTPPQSSTVIVHIKIEDINDSPPVF 687 +F +D +GVI T+ ALDRE A + + A+D P++++ V + + D+ND+ PVF Sbjct: 1270 AFTVDENTGVITTSAALDREKWAAYTFQVFAVDLSPAEPRNTSAQVTVTVLDVNDNAPVF 1329 Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 D L +S + ++A D D G N V Y Sbjct: 1330 IQDPLVIEVSIRHS-QRVLATMKAEDKDFGANGSVFY 1365 Score = 249 bits (609), Expect = 1e-63 Identities = 186/645 (28%), Positives = 305/645 (47%), Gaps = 65/645 (10%) Query: 92 IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151 + SG + TR +LDRE + Y ++V D +P S+T T H+ ++D+NDN P FS Sbjct: 627 LSSTSGEISTRLALDREHQSSYQLVVVVQDGGTPPR---SATGTAHITVLDENDNAPTFS 683 Query: 152 ----EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 ++ + V E + V+ + A D D G N + Y++ G + +F+++ ++G Sbjct: 684 HTRPDRELLLQVVEGLP--SGTVLGTVTAKDPDEGENGTVHYSLSGARAE-RFTLNPMTG 740 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI-RDVNDNAPRFYTSLFQESV 266 ++ L + + Y ++ A D GSP S+T +L I + N S+ +V Sbjct: 741 ELKAASPLRWAERSEYTFMVTAADHGSPGLSSTCRLQIQVLSSARSNLKPNIFSVTMNAV 800 Query: 267 SENVPIGYSI--VRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 E P G I VR Q + ++TY + + D +D G VY +L Sbjct: 801 -EGAPPGSIIGSVRSQNHQQSSSTEGQVTYLVVGGS---DRDGTFMVDRLKGDVYLVREL 856 Query: 325 DRETQAKYQLLVTATDGGDP-PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383 D E ++Y L + +D P S F + + E+ PG Sbjct: 857 DYEKGSRYTLHIEVSDFSQAFPSSHLVQLEINVQDRNDHAPHFTEDPVTIVIPENTEPGA 916 Query: 384 PVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440 V T A D D ++ L Y I ++ G++T+ Q LD + L Sbjct: 917 SVYTFQAIDKDGSGPNSELIYSIEHYWPETHL-LSLDPVSGVLTLGQKLDRESTPSLFLV 975 Query: 441 VSATD-----SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495 V ATD S R + ++ +TD N+ PVF ++P SV ED P+G +L V A D Sbjct: 976 VRATDQTVDPSQRRWGSVTARMFVTDENDNTPVF-SSPSAVSVMEDQPVGFVILYVMARD 1034 Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555 D G N +++Y + + N A +F +NP TG+++ K LDRE + LT+ A D Sbjct: 1035 EDEGENGRVSYRIQA--GNTA-----GRFSLNPNTGSLSILKALDREEQEVFNLTIVAED 1087 Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615 G+P LS + + + V+DVND PVF++ + A ++E+ GT+V +V A D D G NG Sbjct: 1088 HGIPQLSTSQVLSVRVIDVNDEAPVFQRAEFEALVIENKGPGTTVLKVTAVDRDQGSNGH 1147 Query: 616 IHY---------------------ELDPKDRE---------EGSFVIDPASGVIRTNKAL 645 + Y ELD + ++ +G F + P++G + T++ L Sbjct: 1148 VTYGGVTEEGFVINPVTGVITTTKELDTEAQDHYTLTAGDPDGDFHLHPSTGALSTSRGL 1207 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690 DRE+ A + L+ VA D G+P S+TV+V +++ D+ND+ P+F +D Sbjct: 1208 DRETKAEYTLEVVASDRGSPALSTTVMVQVQVMDVNDNSPIFNAD 1252 Score = 223 bits (545), Expect = 6e-56 Identities = 174/575 (30%), Positives = 271/575 (47%), Gaps = 42/575 (7%) Query: 202 IDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF-YTS 260 + S SG++S LD E SY+LV+ QDGG+P RS T I + D NDNAP F +T Sbjct: 627 LSSTSGEISTRLALDREHQSSYQLVVVVQDGGTPPRSATGTAHITVLDENDNAPTFSHTR 686 Query: 261 LFQE---SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317 +E V E +P G + V A D DEG N + Y+++ G T++P +G Sbjct: 687 PDRELLLQVVEGLPSGTVLGTVTAKDPDEGENGTVHYSLS-----GARAERFTLNPMTGE 741 Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL-- 375 + + L +++Y +VTA D G P S+T P + V + Sbjct: 742 LKAASPLRWAERSEYTFMVTAADHGSPGLSSTCRLQIQVLSSARSN--LKPNIFSVTMNA 799 Query: 376 AEDEPPGTPVVTLTATDADE----DNRLHYEITGGNTR-GRFSITSQNGRGLITVAQPLD 430 E PPG+ + ++ + + + + ++ Y + GG+ R G F + G + + + LD Sbjct: 800 VEGAPPGSIIGSVRSQNHQQSSSTEGQVTYLVVGGSDRDGTFMVDRLKGD--VYLVRELD 857 Query: 431 FKQERRYVLTVSATDSGGR---SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 +++ RY L + +D S ++IN+ D N++AP F P T + E+ G + Sbjct: 858 YEKGSRYTLHIEVSDFSQAFPSSHLVQLEINVQDRNDHAPHFTEDPVTIVIPENTEPGAS 917 Query: 488 VLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 V A D D G N+++ YS+ E ++P +G +T + LDRE+ Sbjct: 918 VYTFQAIDKDGSGPNSELIYSI------EHYWPETHLLSLDPVSGVLTLGQKLDRESTPS 971 Query: 547 YLLTVTARDGGV-PSLS--DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 L V A D V PS + + V D NDN PVF ++MED VG + V Sbjct: 972 LFLVVRATDQTVDPSQRRWGSVTARMFVTDENDNTPVFSSPS-AVSVMEDQPVGFVILYV 1030 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 A D D G NGR+ Y + + G F ++P +G + KALDRE +L VA D G Sbjct: 1031 MARDEDEGENGRVSYRIQAGNTA-GRFSLNPNTGSLSILKALDREEQEVFNLTIVAEDHG 1089 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 P S++ ++ +++ D+ND PVF+ + EN GTT+ ++ A D D+G N V Sbjct: 1090 IPQLSTSQVLSVRVIDVNDEAPVFQRAEFEALVIENKGPGTTVLKVTAVDRDQGSNGHVT 1149 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758 Y GG F + G + T +LD E+ Sbjct: 1150 Y---GGVTEEGFVINPVTG----VITTTKELDTEA 1177 Score = 214 bits (523), Expect = 3e-53 Identities = 181/594 (30%), Positives = 278/594 (46%), Gaps = 41/594 (6%) Query: 276 IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA-KYQL 334 + +V A D D G +TY + D TID SG + TS LDR+ A K+ L Sbjct: 19 LAQVSATDEDRGSFGAVTYALGSPSGNTPPD-QFTIDKGSGQLCTSTPLDRDEGADKFDL 77 Query: 335 LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394 VTATDGG S+ A F P Y V L+ PGT VV +TA D D Sbjct: 78 TVTATDGGG--LSSVARVRVSVVDINDNRPAFYPVLYTVSLSTHSSPGTSVVKVTANDPD 135 Query: 395 E--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSD- 451 + R+ Y G F++ G +I++++ L K + ++A D GG + Sbjct: 136 SGLNGRVTYRTVPGGGSAFFTLNKDTG--VISLSRSLHGKANTVISMEIAAEDGGGLTAP 193 Query: 452 -TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510 A V +++ + +PVFE A Y +V ED GT++ VV A+ + G + I YS+SS Sbjct: 194 VNARVNVSVVGGSVTSPVFEQAQYFFTVPEDVLRGTSLGVVRAS-AKTGGSKDILYSISS 252 Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570 + + F ++ TG I T LD ET S L + AR G P+ TT V I+ Sbjct: 253 ---GDPYGY----FTVDSSTGTIRTALPLDHETCSSLELEIQARYGFPPAYG-TTRVRIT 304 Query: 571 VVDVNDNEPVFKQQLYTANIM-EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629 + D+NDN P F + ++ E +GT + + ATD D G NG++ ++L S Sbjct: 305 ISDINDNAPAFLPSSSESLLLPEITKMGTVIYTIQATDRDSGHNGQLSFDLVSAGAAGSS 364 Query: 630 ----FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS--TVIVHIKIEDINDS 683 F +D SG +R +L ESV +DL+ VA DGG P SS T++VHI+ +D Sbjct: 365 GQRTFGVDRGSGEVRLIGSLSYESVPRYDLQVVAKDGGAPQLSSTFTLVVHIQAQDARG- 423 Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 P F++ + EN+P+ T ++RA + + + + Y ++ D+ F + S Sbjct: 424 -PNFDTLTYRVELRENTPLNTQFLQVRALNTEASGGSSISYHLRPDGDAAGFGIM----S 478 Query: 744 DKAELVTMVDLDYESPRKKYELVIRAASPP----LWNDVRVEILVTDVNDNAPVMKDFQI 799 D + LD E + Y L + A+S P V + VTD NDN+P + ++ Sbjct: 479 DSGWIFVRSSLDRE-VKDMYLLTVLASSGPGGAGRTGSATVRVTVTDENDNSPRLSQERV 537 Query: 800 IFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTL 851 ++ FGRV A D D + +L Y++L + +N TG + + Sbjct: 538 FLAVRENLLAGTGFGRVSAIDRDAGLNARLTYKLL--HTDRHFQINSQTGKIII 589 Score = 204 bits (498), Expect = 3e-50 Identities = 165/588 (28%), Positives = 265/588 (45%), Gaps = 21/588 (3%) Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAI--IGGNTQM-QFSIDSLSGDVSLVKTLDYEQ 219 IS T ++A++ ATD D G+ A+ YA+ GNT QF+ID SG + LD ++ Sbjct: 11 ISDTRVSMLAQVSATDEDRGSFGAVTYALGSPSGNTPPDQFTIDKGSGQLCTSTPLDRDE 70 Query: 220 -VRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR 278 + L + A DGG S+ ++ +++ D+NDN P FY L+ S+S + G S+V+ Sbjct: 71 GADKFDLTVTATDGGG--LSSVARVRVSVVDINDNRPAFYPVLYTVSLSTHSSPGTSVVK 128 Query: 279 VQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA 338 V A D D G+N +TY + G T++ +G + S L + + + A Sbjct: 129 VTANDPDSGLNGRVTY----RTVPGGGSAFFTLNKDTGVISLSRSLHGKANTVISMEIAA 184 Query: 339 TDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR 398 DGG A F QY + ED GT + + A+ ++ Sbjct: 185 EDGGGLTAPVNARVNVSVVGGSVTSPVFEQAQYFFTVPEDVLRGTSLGVVRASAKTGGSK 244 Query: 399 -LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS-DTAMVQ 456 + Y I+ G+ G F++ S G I A PLD + L + A + T V+ Sbjct: 245 DILYSISSGDPYGYFTVDSST--GTIRTALPLDHETCSSLELEIQARYGFPPAYGTTRVR 302 Query: 457 INITDANNYAPVF-ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515 I I+D N+ AP F ++ + + E +GT + + ATD D G N Q+++ L S + Sbjct: 303 ITISDINDNAPAFLPSSSESLLLPEITKMGTVIYTIQATDRDSGHNGQLSFDLVS--AGA 360 Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575 A + + F ++ +G + L E++ Y L V A+DGG P LS T + + + + Sbjct: 361 AGSSGQRTFGVDRGSGEVRLIGSLSYESVPRYDLQVVAKDGGAPQLSSTFTLVVHIQAQD 420 Query: 576 DNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA 635 P F Y + E+ + T QV A + + I Y L P D + F I Sbjct: 421 ARGPNFDTLTYRVELRENTPLNTQFLQVRALNTEASGGSSISYHLRP-DGDAAGFGIMSD 479 Query: 636 SGVIRTNKALDRESVATHDLKAVAIDG-GTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694 SG I +LDRE + L +A G G ++ + V + + D ND+ P + + Sbjct: 480 SGWIFVRSSLDREVKDMYLLTVLASSGPGGAGRTGSATVRVTVTDENDNSPRLSQERVFL 539 Query: 695 YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 + EN GT G + A D D G NA + Y + D F + ++ G Sbjct: 540 AVRENLLAGTGFGRVSAIDRDAGLNARLTYKLLHTD--RHFQINSQTG 585 Score = 195 bits (475), Expect = 2e-47 Identities = 175/629 (27%), Positives = 283/629 (44%), Gaps = 37/629 (5%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATD--QASPVSDRLSSTATIHVNIIDDNDNY 147 F +D G + LD EK +RYT+ ++ +D QA P S + + +N+ D ND+ Sbjct: 841 FMVDRLKGDVYLVRELDYEKGSRYTLHIEVSDFSQAFPSSHLVQ----LEINVQDRNDHA 896 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSAIRYAI--IGGNTQMQFSIDS 204 P F+E T+ + E+ + +A D D G NS + Y+I T + S+D Sbjct: 897 PHFTEDPVTIVIPENTE--PGASVYTFQAIDKDGSGPNSELIYSIEHYWPETHL-LSLDP 953 Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQD---GGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261 +SG ++L + LD E S LV+RA D S R + + + D NDN P F +S Sbjct: 954 VSGVLTLGQKLDRESTPSLFLVVRATDQTVDPSQRRWGSVTARMFVTDENDNTPVF-SSP 1012 Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321 SV E+ P+G+ I+ V A D DEG N ++Y + GN +++P +G + Sbjct: 1013 SAVSVMEDQPVGFVILYVMARDEDEGENGRVSYRIQ----AGNTAGRFSLNPNTGSLSIL 1068 Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381 LDRE Q + L + A D G P S + F ++E + E++ P Sbjct: 1069 KALDREEQEVFNLTIVAEDHGIPQLSTSQVLSVRVIDVNDEAPVFQRAEFEALVIENKGP 1128 Query: 382 GTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441 GT V+ +TA D D+ + H GG T F I G +IT + LD + + Y LT Sbjct: 1129 GTTVLKVTAVDRDQGSNGHVTY-GGVTEEGFVINPVTG--VITTTKELDTEAQDHYTLTA 1185 Query: 442 SATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501 D + ++ + + E + +P +T ++V DV N Sbjct: 1186 GDPDGDFHLHPSTGALSTSRGLDRETKAEYTLEVVASDRGSPALSTTVMVQVQVMDVNDN 1245 Query: 502 AQITYSLSSEISNEAVAHHDQQ----FVINPQTGAITTNKLLDRETMSGYLLTVTARDGG 557 + I ++ ++ + + Q F ++ TG ITT+ LDRE + Y V A D Sbjct: 1246 SPI-FNADDALNGKFLYFLSQDAHGAFTVDENTGVITTSAALDREKWAAYTFQVFAVDLS 1304 Query: 558 VPSLSDTT-DVEISVVDVNDNEPVFKQQ--LYTANIMEDALVGTSVSQVGATDADVGLNG 614 +T+ V ++V+DVNDN PVF Q + +I V ++ + A D D G NG Sbjct: 1305 PAEPRNTSAQVTVTVLDVNDNAPVFIQDPLVIEVSIRHSQRV---LATMKAEDKDFGANG 1361 Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674 + Y + F I+ +G I+ + L + A L A+D G+P QS+ +V Sbjct: 1362 SVFYRFATPVK---GFSINSLTGEIQATEPLQDLTQAQRTLIVEAMDQGSPAQSAQGVVV 1418 Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIG 703 I ++++ + F + I EN+ G Sbjct: 1419 IYVKEVVYNGIRFSRNARDVSIQENAAKG 1447 Score = 194 bits (474), Expect = 2e-47 Identities = 171/608 (28%), Positives = 258/608 (42%), Gaps = 50/608 (8%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELV 65 + +INV D NDH+P F + E G +V T +A D+D G N+E+ Y+IE Sbjct: 883 VQLEINVQDRNDHAPHFTEDPVTIVIPENTEPGASVYTFQAIDKDGSGPNSELIYSIEHY 942 Query: 66 TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125 +T + +D SG L LDRE ++V+ATDQ Sbjct: 943 WPET------------------HLLSLDPVSGVLTLGQKLDRESTPSLFLVVRATDQTVD 984 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 S R + T + + D+NDN P FS + VSV ED V VI + A D D G N Sbjct: 985 PSQRRWGSVTARMFVTDENDNTPVFSSPS-AVSVMEDQPV--GFVILYVMARDEDEGENG 1041 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 + Y I GNT +FS++ +G +S++K LD E+ + L I A+D G P S + L + Sbjct: 1042 RVSYRIQAGNTAGRFSLNPNTGSLSILKALDREEQEVFNLTIVAEDHGIPQLSTSQVLSV 1101 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 + DVND AP F + F+ V EN G ++++V A D D+G N +T Y G Sbjct: 1102 RVIDVNDEAPVFQRAEFEALVIENKGPGTTVLKVTAVDRDQGSNGHVT-------YGGVT 1154 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 + I+P +G + T+ +LD E Q Y L DG +T Sbjct: 1155 EEGFVINPVTGVITTTKELDTEAQDHYTLTAGDPDGDFHLHPSTGALSTSRGLDRETKAE 1214 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRF--------SITSQ 417 + + T +V + D ++++ + N + + + T Sbjct: 1215 YTLEVVASDRGSPALSTTVMVQVQVMDVNDNSPIFNADDALNGKFLYFLSQDAHGAFTVD 1274 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATD---SGGRSDTAMVQINITDANNYAPVFENAPY 474 G+IT + LD ++ Y V A D + R+ +A V + + D N+ APVF P Sbjct: 1275 ENTGVITTSAALDREKWAAYTFQVFAVDLSPAEPRNTSAQVTVTVLDVNDNAPVFIQDPL 1334 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 V + + A D D G N + Y ++ + F IN TG I Sbjct: 1335 VIEV-SIRHSQRVLATMKAEDKDFGANGSVFYRFATPVKG---------FSINSLTGEIQ 1384 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 + L T + L V A D G P+ S V I V +V N F + +I E+A Sbjct: 1385 ATEPLQDLTQAQRTLIVEAMDQGSPAQSAQGVVVIYVKEVVYNGIRFSRNARDVSIQENA 1444 Query: 595 LVGTSVSQ 602 G + Q Sbjct: 1445 AKGEIMVQ 1452 Score = 194 bits (473), Expect = 3e-47 Identities = 162/562 (28%), Positives = 257/562 (45%), Gaps = 33/562 (5%) Query: 88 DVFRIDGRSGALLTRASLDREKVA-RYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146 D F ID SG L T LDR++ A ++ + V ATD LSS A + V+++D NDN Sbjct: 49 DQFTIDKGSGQLCTSTPLDRDEGADKFDLTVTATDGGG-----LSSVARVRVSVVDINDN 103 Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206 P F YTVS+ S + K+ A D D G N + Y + G F+++ + Sbjct: 104 RPAFYPVLYTVSLSTHSS--PGTSVVKVTANDPDSGLNGRVTYRTVPGGGSAFFTLNKDT 161 Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266 G +SL ++L + + I A+DGG + ++ +++ + +P F + + +V Sbjct: 162 GVISLSRSLHGKANTVISMEIAAEDGGGLTAPVNARVNVSVVGGSVTSPVFEQAQYFFTV 221 Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326 E+V G S+ V+A A G + ++ Y+++ D G T+D +G + T+ LD Sbjct: 222 PEDVLRGTSLGVVRA-SAKTGGSKDILYSISSGDPYGY----FTVDSSTGTIRTALPLDH 276 Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE-VELAEDEPPGTPV 385 ET + +L + A G PP T F+P E + L E GT + Sbjct: 277 ETCSSLELEIQAR-YGFPPAYGTTRVRITISDINDNAPAFLPSSSESLLLPEITKMGTVI 335 Query: 386 VTLTATDAD--EDNRLHYEIT---GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440 T+ ATD D + +L +++ + G+ + G G + + L ++ RY L Sbjct: 336 YTIQATDRDSGHNGQLSFDLVSAGAAGSSGQRTFGVDRGSGEVRLIGSLSYESVPRYDLQ 395 Query: 441 VSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498 V A D G S T + ++I + P F+ Y + E+ P+ T L V A +++ Sbjct: 396 VVAKDGGAPQLSSTFTLVVHIQAQDARGPNFDTLTYRVELRENTPLNTQFLQVRALNTEA 455 Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG-G 557 + I+Y L + +A F I +G I LDRE YLLTV A G G Sbjct: 456 SGGSSISYHLRPD--GDAAG-----FGIMSDSGWIFVRSSLDREVKDMYLLTVLASSGPG 508 Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617 + + V ++V D NDN P Q+ + E+ L GT +V A D D GLN R+ Sbjct: 509 GAGRTGSATVRVTVTDENDNSPRLSQERVFLAVRENLLAGTGFGRVSAIDRDAGLNARLT 568 Query: 618 YELDPKDREEGSFVIDPASGVI 639 Y+L DR F I+ +G I Sbjct: 569 YKLLHTDRH---FQINSQTGKI 587 Score = 184 bits (449), Expect = 2e-44 Identities = 176/588 (29%), Positives = 258/588 (43%), Gaps = 46/588 (7%) Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 + + SG + T LDRE Q+ YQL+V DGG PPRSAT T F Sbjct: 625 LCLSSTSGEISTRLALDREHQSSYQLVVVVQDGGTPPRSATGTAHITVLDENDNAPTFSH 684 Query: 369 GQYEVEL----AEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGL 422 + + EL E P GT + T+TA D D E+ +HY ++G RF++ G Sbjct: 685 TRPDRELLLQVVEGLPSGTVLGTVTAKDPDEGENGTVHYSLSGARAE-RFTLNPMTGE-- 741 Query: 423 ITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDA--NNYAP-VFENAPYTAS 477 + A PL + + Y V+A D G G S T +QI + + +N P +F T + Sbjct: 742 LKAASPLRWAERSEYTFMVTAADHGSPGLSSTCRLQIQVLSSARSNLKPNIFS---VTMN 798 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ--FVINPQTGAITT 535 E AP G+ ++ + S N Q + S +++ V D+ F+++ G + Sbjct: 799 AVEGAPPGS---IIGSVRSQ---NHQQSSSTEGQVTYLVVGGSDRDGTFMVDRLKGDVYL 852 Query: 536 NKLLDRETMSGYLLTVTARD--GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593 + LD E S Y L + D PS S +EI+V D ND+ P F + T I E+ Sbjct: 853 VRELDYEKGSRYTLHIEVSDFSQAFPS-SHLVQLEINVQDRNDHAPHFTEDPVTIVIPEN 911 Query: 594 ALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652 G SV A D D G N + Y ++ E +DP SGV+ + LDRES + Sbjct: 912 TEPGASVYTFQAIDKDGSGPNSELIYSIEHYWPETHLLSLDPVSGVLTLGQKLDRESTPS 971 Query: 653 HDLKAVAIDGGTPPQS---STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 L A D P +V + + D ND+ PVF S + E+ P+G I + Sbjct: 972 LFLVVRATDQTVDPSQRRWGSVTARMFVTDENDNTPVFSSPS-AVSVMEDQPVGFVILYV 1030 Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 A D DEG N V Y I+ G+ + FSL GS L + LD E ++ + L I A Sbjct: 1031 MARDEDEGENGRVSYRIQAGNTAGRFSLNPNTGS----LSILKALDREE-QEVFNLTIVA 1085 Query: 770 AS---PPLWNDVRVEILVTDVNDNAPVMK--DFQIIFNNYKDCFPVGPFGRVPAYDADVT 824 P L + + V DVND APV + +F+ + K P +V A D D Sbjct: 1086 EDHGIPQLSTSQVLSVRVIDVNDEAPVFQRAEFEALVIENKG--PGTTVLKVTAVDRDQG 1143 Query: 825 DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 + G ++N TG +T + +L+T T+ DG Sbjct: 1144 SN-GHVTYGGVTEEGFVINPVTGVITTTKELDTEAQDHYTLTAGDPDG 1190 Score = 175 bits (425), Expect = 2e-41 Identities = 155/534 (29%), Positives = 239/534 (44%), Gaps = 50/534 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +++V+D ND+ P F Y S+ +S GT+V+ + A D D G N V Y Sbjct: 94 RVSVVDINDNRPAFYPVLYTVSLSTHSSPGTSVVKVTANDPDSGLNGRVTYRTV------ 147 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD---QASPV 126 P F ++ +G + SL + ++ + A D +PV Sbjct: 148 --PGGGSA-----------FFTLNKDTGVISLSRSLHGKANTVISMEIAAEDGGGLTAPV 194 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 + R+ +V+++ + P F + Y +V ED V + ++A+ A G + Sbjct: 195 NARV------NVSVVGGSVTSPVFEQAQYFFTVPED--VLRGTSLGVVRAS-AKTGGSKD 245 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 I Y+I G+ F++DS +G + LD+E S L I+A+ G P+ TT++ I Sbjct: 246 ILYSISSGDPYGYFTVDSSTGTIRTALPLDHETCSSLELEIQARYGFPPA-YGTTRVRIT 304 Query: 247 IRDVNDNAPRFYTSLFQE-SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 I D+NDNAP F S + + E +G I +QA D D G N +L++ + G+ Sbjct: 305 ISDINDNAPAFLPSSSESLLLPEITKMGTVIYTIQATDRDSGHNGQLSFDLVSAGAAGSS 364 Query: 306 -DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 +D SG V G L E+ +Y L V A DGG P S+T T Sbjct: 365 GQRTFGVDRGSGEVRLIGSLSYESVPRYDLQVVAKDGGAPQLSSTFTLVVHIQAQDARGP 424 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTA--TDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422 F Y VEL E+ P T + + A T+A + + Y + F I S + G Sbjct: 425 NFDTLTYRVELRENTPLNTQFLQVRALNTEASGGSSISYHLRPDGDAAGFGIMSDS--GW 482 Query: 423 ITVAQPLDFKQERRYVLTVSATD---SGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479 I V LD + + Y+LTV A+ GR+ +A V++ +TD N+ +P +V Sbjct: 483 IFVRSSLDREVKDMYLLTVLASSGPGGAGRTGSATVRVTVTDENDNSPRLSQERVFLAVR 542 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 E+ GT VSA D D G+NA++TY L H D+ F IN QTG I Sbjct: 543 ENLLAGTGFGRVSAIDRDAGLNARLTYKL---------LHTDRHFQINSQTGKI 587 Score = 157 bits (382), Expect = 3e-36 Identities = 127/412 (30%), Positives = 197/412 (47%), Gaps = 23/412 (5%) Query: 372 EVELAEDEPPGTPVVTLTATDADEDN--RLHYEI--TGGNTRGRFSITSQNGRGLITVAQ 427 E LA + + + ++ATD D + + Y + GNT T G G + + Sbjct: 6 EPVLAISDTRVSMLAQVSATDEDRGSFGAVTYALGSPSGNTPPD-QFTIDKGSGQLCTST 64 Query: 428 PLDFKQER-RYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 PLD + ++ LTV+ATD GG S A V++++ D N+ P F YT S+ + GT Sbjct: 65 PLDRDEGADKFDLTVTATDGGGLSSVARVRVSVVDINDNRPAFYPVLYTVSLSTHSSPGT 124 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 +V+ V+A D D G+N ++TY + A F +N TG I+ ++ L + + Sbjct: 125 SVVKVTANDPDSGLNGRVTY---RTVPGGGSAF----FTLNKDTGVISLSRSLHGKANTV 177 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 + + A DGG + V +SVV + PVF+Q Y + ED L GTS+ V A+ Sbjct: 178 ISMEIAAEDGGGLTAPVNARVNVSVVGGSVTSPVFEQAQYFFTVPEDVLRGTSLGVVRAS 237 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 A G + I Y + D G F +D ++G IRT LD E+ ++ +L+ + G PP Sbjct: 238 -AKTGGSKDILYSISSGD-PYGYFTVDSSTGTIRTALPLDHETCSSLELE-IQARYGFPP 294 Query: 667 QSSTVIVHIKIEDINDSPPVF-ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 T V I I DIND+ P F S + + E + +GT I I+A D D G N + + Sbjct: 295 AYGTTRVRITISDINDNAPAFLPSSSESLLLPEITKMGTVIYTIQATDRDSGHNGQLSFD 354 Query: 726 IKGGDDSNSFSLET---RQGSDKAELVTMVDLDYES-PRKKYELVIRAASPP 773 + + S T +GS + L+ L YES PR ++V + P Sbjct: 355 LVSAGAAGSSGQRTFGVDRGSGEVRLIG--SLSYESVPRYDLQVVAKDGGAP 404 Score = 128 bits (309), Expect = 2e-27 Identities = 115/450 (25%), Positives = 199/450 (44%), Gaps = 41/450 (9%) Query: 1 MSVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEY 60 ++ P ++V+ + SPVFE QY +V E GT++ ++A+ + G + ++ Y Sbjct: 190 LTAPVNARVNVSVVGGSVTSPVFEQAQYFFTVPEDVLRGTSLGVVRASAKT-GGSKDILY 248 Query: 61 TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT 120 +I + D F +D +G + T LD E + + ++A Sbjct: 249 SIS--SGDPYG-----------------YFTVDSSTGTIRTALPLDHETCSSLELEIQAR 289 Query: 121 DQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD 180 P T + + I D NDN P F + + +I+ VI I+ATD D Sbjct: 290 YGFPPAY----GTTRVRITISDINDNAPAFLPSSSESLLLPEITKMGT-VIYTIQATDRD 344 Query: 181 VGANSAIRYAII-----GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP 235 G N + + ++ G + Q F +D SG+V L+ +L YE V Y L + A+DGG+P Sbjct: 345 SGHNGQLSFDLVSAGAAGSSGQRTFGVDRGSGEVRLIGSLSYESVPRYDLQVVAKDGGAP 404 Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295 S+T L+++I+ + P F T ++ + EN P+ ++V+A + + + ++Y Sbjct: 405 QLSSTFTLVVHIQAQDARGPNFDTLTYRVELRENTPLNTQFLQVRALNTEASGGSSISYH 464 Query: 296 M-TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG-GDPPRSATATXX 353 + D D G I SGW++ LDRE + Y L V A+ G G R+ +AT Sbjct: 465 LRPDGDAAG-----FGIMSDSGWIFVRSSLDREVKDMYLLTVLASSGPGGAGRTGSATVR 519 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGR 411 + + + E+ GT ++A D D + RL Y++ +T Sbjct: 520 VTVTDENDNSPRLSQERVFLAVRENLLAGTGFGRVSAIDRDAGLNARLTYKLL--HTDRH 577 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTV 441 F I SQ G+ +I + + R L + Sbjct: 578 FQINSQTGKIIIPITDIKELHSSIRVQLLI 607 Score = 115 bits (276), Expect = 2e-23 Identities = 81/251 (32%), Positives = 133/251 (52%), Gaps = 12/251 (4%) Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 D IGT + +V T +DV + ++YSL + + + + N +GA+ + LD Sbjct: 1567 DMLIGTEITLV--TGNDVDSSPALSYSLQLDPTALGMFGIHRY---NQWSGALRLQRALD 1621 Query: 541 RETMSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 RE S + + + A DG G +L+ V + V DVNDN P F ++ TA+I E+ ++ Sbjct: 1622 REHQSTHTVIIQATDGQGHFALAP---VVVEVKDVNDNHPFFPVEVLTASIRENQPANSA 1678 Query: 600 VSQVGATDADVGLNGRIHY-ELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 V+ + A D D G+ G + Y L+ + SF +DP SG IR+ D E + + + A+ Sbjct: 1679 VTVLHAIDHDTGVFGHLKYFMLERTGTGKESFSVDPNSGEIRSKIPFDFEKINSFNFVAM 1738 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 AID G S+TV V + + ++ PVF S +F + E + G +IG+++A+D D G Sbjct: 1739 AIDSGN--HSATVTVQVFVTGEDEYDPVFLSQDFSFEVPEGAKKGQSIGQVQANDEDGGV 1796 Query: 719 NAVVHYSIKGG 729 + +V YS G Sbjct: 1797 DGIVLYSFPTG 1807 Score = 94.7 bits (225), Expect = 3e-17 Identities = 65/209 (31%), Positives = 104/209 (49%), Gaps = 11/209 (5%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 + R + SGAL + +LDRE + +TV+++ATD + A + V + D NDN+P Sbjct: 1604 IHRYNQWSGALRLQRALDREHQSTHTVIIQATDGQGHF-----ALAPVVVEVKDVNDNHP 1658 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII--GGNTQMQFSIDSLS 206 F + T S+ E+ N + + A D D G ++Y ++ G + FS+D S Sbjct: 1659 FFPVEVLTASIRENQPA--NSAVTVLHAIDHDTGVFGHLKYFMLERTGTGKESFSVDPNS 1716 Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266 G++ D+E++ S+ V A D G+ S + T Q+ + D D P F + F V Sbjct: 1717 GEIRSKIPFDFEKINSFNFVAMAIDSGNHSATVTVQVFVTGEDEYD--PVFLSQDFSFEV 1774 Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYT 295 E G SI +VQA D D GV+ + Y+ Sbjct: 1775 PEGAKKGQSIGQVQANDEDGGVDGIVLYS 1803 Score = 79.8 bits (188), Expect = 1e-12 Identities = 59/222 (26%), Positives = 97/222 (43%), Gaps = 10/222 (4%) Query: 177 TDADVGANSAIRYAIIGGNTQM-QFSI---DSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232 T DV ++ A+ Y++ T + F I + SG + L + LD E ++ ++I+A DG Sbjct: 1578 TGNDVDSSPALSYSLQLDPTALGMFGIHRYNQWSGALRLQRALDREHQSTHTVIIQATDG 1637 Query: 233 GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292 +++ ++DVNDN P F + S+ EN P ++ + A D D GV L Sbjct: 1638 --QGHFALAPVVVEVKDVNDNHPFFPVEVLTASIRENQPANSAVTVLHAIDHDTGVFGHL 1695 Query: 293 TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352 Y M ++ TG ++DP SG + + D E + + A D G+ SAT T Sbjct: 1696 KYFMLERTGTGKES--FSVDPNSGEIRSKIPFDFEKINSFNFVAMAIDSGN--HSATVTV 1751 Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394 F+ + E+ E G + + A D D Sbjct: 1752 QVFVTGEDEYDPVFLSQDFSFEVPEGAKKGQSIGQVQANDED 1793 Score = 77.8 bits (183), Expect = 4e-12 Identities = 124/521 (23%), Positives = 198/521 (38%), Gaps = 58/521 (11%) Query: 11 INVLDCNDHSPVFEMQQY--EASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68 + VLD ND++PVF E S+R S + T+KA D+D G N V Y Sbjct: 1317 VTVLDVNDNAPVFIQDPLVIEVSIRH---SQRVLATMKAEDKDFGANGSVFYRFATPVKG 1373 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 F I+ +G + L A+ T++V+A DQ SP Sbjct: 1374 ---------------------FSINSLTGEIQATEPLQDLTQAQRTLIVEAMDQGSPAQ- 1411 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-------- 180 S+ + + + + N +FS VS+ E+ + ++ K D + Sbjct: 1412 --SAQGVVVIYVKEVVYNGIRFSRNARDVSIQEN-AAKGEIMVQSSKGLDFEDTPRLRLV 1468 Query: 181 VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDY-EQVRSYRLVIR---AQDGGSPS 236 V A S + + N +Q D+L L + Y + + Y + I A+D Sbjct: 1469 VKAESVSSTSFMAINLILQDVNDNLPR-FQLQNYIAYMREAQGYDMPIIQVVAEDVDQGQ 1527 Query: 237 RSNTTQLLINIRDVNDNAPRFY-------TSLFQESVSENVPIGYSIVRVQAYDADEGVN 289 ++ + NA F+ T F ++ IG I V D D + Sbjct: 1528 NGQEVRIPESNYISCQNAHSFFCFLKFYLTCFFVFFFPLDMLIGTEITLVTGNDVDS--S 1585 Query: 290 AELTYTMT-DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348 L+Y++ D G + + SG + LDRE Q+ + +++ ATDG A Sbjct: 1586 PALSYSLQLDPTALGMFGIH-RYNQWSGALRLQRALDREHQSTHTVIIQATDGQG--HFA 1642 Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGG 406 A F + E++P + V L A D D L Y + Sbjct: 1643 LAPVVVEVKDVNDNHPFFPVEVLTASIRENQPANSAVTVLHAIDHDTGVFGHLKYFMLER 1702 Query: 407 NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYA 466 G+ S + G I P DF++ + A DSG S T VQ+ +T + Y Sbjct: 1703 TGTGKESFSVDPNSGEIRSKIPFDFEKINSFNFVAMAIDSGNHSATVTVQVFVTGEDEYD 1762 Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507 PVF + ++ V E A G ++ V A D D G++ + YS Sbjct: 1763 PVFLSQDFSFEVPEGAKKGQSIGQVQANDEDGGVDGIVLYS 1803 Score = 59.7 bits (138), Expect = 1e-06 Identities = 43/170 (25%), Positives = 73/170 (42%), Gaps = 4/170 (2%) Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765 + ++ A D D G V Y++ G N+ + +L T LD + K++L Sbjct: 19 LAQVSATDEDRGSFGAVTYAL-GSPSGNTPPDQFTIDKGSGQLCTSTPLDRDEGADKFDL 77 Query: 766 VIRAASPPLWNDV-RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD-- 822 + A + V RV + V D+NDN P + P +V A D D Sbjct: 78 TVTATDGGGLSSVARVRVSVVDINDNRPAFYPVLYTVSLSTHSSPGTSVVKVTANDPDSG 137 Query: 823 VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 + ++ YR + G + LN+ TG ++LS L+ + +ME++ DG Sbjct: 138 LNGRVTYRTVPGGGSAFFTLNKDTGVISLSRSLHGKANTVISMEIAAEDG 187 Score = 40.7 bits (91), Expect = 0.57 Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 8/74 (10%) Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVR 779 HY++ GD F L G+ L T LD E+ + +Y L + A+ SP L V Sbjct: 1180 HYTLTAGDPDGDFHLHPSTGA----LSTSRGLDRET-KAEYTLEVVASDRGSPALSTTVM 1234 Query: 780 VEILVTDVNDNAPV 793 V++ V DVNDN+P+ Sbjct: 1235 VQVQVMDVNDNSPI 1248 Score = 37.9 bits (84), Expect = 4.0 Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 7/85 (8%) Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV--DVNDNEPVFKQQLYTANI 590 + ++K LD E L V A S+S T+ + I+++ DVNDN P F+ Q Y A + Sbjct: 1451 VQSSKGLDFEDTPRLRLVVKAE-----SVSSTSFMAINLILQDVNDNLPRFQLQNYIAYM 1505 Query: 591 MEDALVGTSVSQVGATDADVGLNGR 615 E + QV A D D G NG+ Sbjct: 1506 REAQGYDMPIIQVVAEDVDQGQNGQ 1530 >UniRef50_A7SN99 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 943 Score = 276 bits (676), Expect = 7e-72 Identities = 251/889 (28%), Positives = 397/889 (44%), Gaps = 101/889 (11%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ + D ND++PVF Y SV+E + GTT +KATD D G+NA ++Y+I Sbjct: 121 RVQIEDVNDNTPVFINTPYSISVKEN-TLGTTGFAVKATDADQGQNALIKYSIT------ 173 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 +A VF G LD EK + + V A+D R Sbjct: 174 -GGNEANMFKIGAYEGTISVFPDSG---------VLDYEKYKSFNLTVSASDLGGVNGSR 223 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + T+ + + + D +D FS YT V E S T + + A D D+ N + Y Sbjct: 224 TAVTS-VFIRVEDVDDLPAVFSPDYYTAKVAE--SSTKGFYVTTVTARDGDLSLNKPVSY 280 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I G T + +S + + T+ ++ V T Q I I D Sbjct: 281 FIDQGITTSPQHYEPVSSSIKAISTI-------HKAVFA-----------TVQ--ITITD 320 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 +NDNAP+F + +V EN P G +++RV A DAD G NA+ TY++T G Sbjct: 321 INDNAPKFVNLPYSGTVPENSPTGLTVLRVTAQDADSGDNAKFTYSLTGA--AGKF---- 374 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 + G+V SG +DRETQ Y+ V+ +D P + P Sbjct: 375 -VVSSEGYVVVSGNIDRETQDTYEFKVSVSDADLGPNADVRFSFIPDSSGLDKLFTIDPV 433 Query: 370 QYEVE-LA----EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG----- 419 +++ LA E+ + + + + R Y R R + T++ G Sbjct: 434 SGDIKTLATFDREERVSYGLGIRVIDQPSGQQGRYVYIANKRFIRSRDNQTTRKGDNIAN 493 Query: 420 ----RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAP-Y 474 GL+ + LD + Y L V ATD GG+ T+ + + + D N+ APVF Y Sbjct: 494 KRGNSGLVKTSSSLDRETTPVYTLVVRATDGGGKEVTSSLTVILDDVNDNAPVFSRPEGY 553 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 T V ++ +G +V V ATD D GINA YSL S VA + +F+I+ +TG I Sbjct: 554 TFEV-QEGGVGLSVGTVQATDRDSGINAATLYSLKS------VADY-SKFIIDSKTGVIK 605 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 T+ LDRET + V ARD G P LS + ++V D+ND+ P F Q+ Y+ + E Sbjct: 606 TSFSLDRETQDQLNIRVIARDTGSPQLSAEVGIIVNVTDINDHRPAFSQRQYSVTVQEKR 665 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654 + + ATD+D G+N +HY +D SF +D +G + T LDRE A + Sbjct: 666 -ASHVILTLTATDSDRGINSALHYMID-SGNFGNSFTLDALTGSLSTTGPLDREVRAEYT 723 Query: 655 LKAVAID--GGTP---PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 L D G P + +V++ IED+ND+ PVF + I E++ GT I ++ Sbjct: 724 LLVFVSDLQGNASLGIPLRDSAVVNVFIEDMNDNSPVFPQSQYSLTIPEDTAPGTGIIQV 783 Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 +A D D G + +HYSI G+ F ++ S A + LD + PR + + Sbjct: 784 QARDIDSGISQNLHYSIVSGNSLGRFFID----SSSARVYVKSPLDRDPPRNEGAYTL-- 837 Query: 770 ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVGPFGRVPA---YDADVTD 825 V I ++DVND+ P Q +++ + +G P+ D Sbjct: 838 ---------EVTITISDVNDSPPEFS--QAMYSVRIPENITLGTVVLQPSCVDRDLGTNG 886 Query: 826 KLQYRILSGNNAN--LILLNETTGSMTLSPQLNTNV-PKLATMEVSVTD 871 ++ Y I SGN+ +N ++G++++S + + + K ++ ++ TD Sbjct: 887 QISYHISSGNSETPPRFSVNPSSGALSVSTEFDFDTGRKSYSLVLTATD 935 Score = 263 bits (645), Expect = 4e-68 Identities = 255/915 (27%), Positives = 410/915 (44%), Gaps = 103/915 (11%) Query: 21 PVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXX 80 P F QY + E +GT VLT++A D + N ++ Y L+ ED Sbjct: 27 PRFVETQYVGRLPENQPTGTGVLTVRAVDNE---NDQITYQ--------LSGEDGR---- 71 Query: 81 XXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVL-VKATD-QASPVSDRLSSTATIHV 138 F+I+ +G + + ++DREK+ +L KA A + V Sbjct: 72 ---------FKINSVTGEITSNVNIDREKLPGSNLLEFKAIAYDAKGAGYDYRVDVPVRV 122 Query: 139 NIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQM 198 I D NDN P F Y++SV E+ T +KATDAD G N+ I+Y+I GGN Sbjct: 123 QIEDVNDNTPVFINTPYSISVKENTLGTTG---FAVKATDADQGQNALIKYSITGGNEAN 179 Query: 199 QFSIDSLSGDVSLVK---TLDYEQVRSYRLVIRAQD--GGSPSRSNTTQLLINIRDVNDN 253 F I + G +S+ LDYE+ +S+ L + A D G + SR+ T + I + DV+D Sbjct: 180 MFKIGAYEGTISVFPDSGVLDYEKYKSFNLTVSASDLGGVNGSRTAVTSVFIRVEDVDDL 239 Query: 254 APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313 F + V+E+ G+ + V A D D +N ++Y + D+ T + P +P Sbjct: 240 PAVFSPDYYTAKVAESSTKGFYVTTVTARDGDLSLNKPVSYFI-DQGITTS---PQHYEP 295 Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373 S + + + A Q+ +T + P F+ Y Sbjct: 296 VSSSIKAISTIHKAVFATVQITITDINDNAPK--------------------FVNLPYSG 335 Query: 374 ELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431 + E+ P G V+ +TA DAD DN + Y +TG G+F ++S+ G + V+ +D Sbjct: 336 TVPENSPTGLTVLRVTAQDADSGDNAKFTYSLTG--AAGKFVVSSE---GYVVVSGNIDR 390 Query: 432 KQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPY-----TASVFEDAPIGT 486 + + Y VS +D+ + + I D++ +F P T + F+ + Sbjct: 391 ETQDTYEFKVSVSDADLGPNADVRFSFIPDSSGLDKLFTIDPVSGDIKTLATFDREERVS 450 Query: 487 TVLVVSATDSDVGINAQITYSLSSEI----SNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 L + D G + Y + N+ D +G + T+ LDRE Sbjct: 451 YGLGIRVIDQPSGQQGRYVYIANKRFIRSRDNQTTRKGDNIANKRGNSGLVKTSSSLDRE 510 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF-KQQLYTANIMEDALVGTSVS 601 T Y L V A DGG + T+ + + + DVNDN PVF + + YT + E VG SV Sbjct: 511 TTPVYTLVVRATDGGGKEV--TSSLTVILDDVNDNAPVFSRPEGYTFEVQEGG-VGLSVG 567 Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 V ATD D G+N Y L + F+ID +GVI+T+ +LDRE+ +++ +A D Sbjct: 568 TVQATDRDSGINAATLYSL-KSVADYSKFIIDSKTGVIKTSFSLDRETQDQLNIRVIARD 626 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 G+P S+ V + + + DIND P F + + E I + A D D G N+ Sbjct: 627 TGSPQLSAEVGIIVNVTDINDHRPAFSQRQYSVTVQEKR-ASHVILTLTATDSDRGINSA 685 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI--------RAASPP 773 +HY I G+ NSF+L+ GS L T LD E R +Y L++ + P Sbjct: 686 LHYMIDSGNFGNSFTLDALTGS----LSTTGPLDRE-VRAEYTLLVFVSDLQGNASLGIP 740 Query: 774 LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRI 831 L + V + + D+NDN+PV Q +D P +V A D D ++ L Y I Sbjct: 741 LRDSAVVNVFIEDMNDNSPVFPQSQYSLTIPEDTAPGTGIIQVQARDIDSGISQNLHYSI 800 Query: 832 LSGNNANLILLNETTGSMTLSPQLNTNVPK---LATMEVSVT-DGVNEIK---AMMQLSV 884 +SGN+ ++ ++ + + L+ + P+ T+EV++T VN+ + SV Sbjct: 801 VSGNSLGRFFIDSSSARVYVKSPLDRDPPRNEGAYTLEVTITISDVNDSPPEFSQAMYSV 860 Query: 885 RLITEEMLLNSITVR 899 R I E + L ++ ++ Sbjct: 861 R-IPENITLGTVVLQ 874 Score = 214 bits (522), Expect = 3e-53 Identities = 161/480 (33%), Positives = 240/480 (50%), Gaps = 44/480 (9%) Query: 94 GRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDD-NDNYPQFSE 152 G SG + T +SLDRE YT++V+ATD ++S+ T+ I+DD NDN P FS Sbjct: 496 GNSGLVKTSSSLDRETTPVYTLVVRATDGGGK---EVTSSLTV---ILDDVNDNAPVFSR 549 Query: 153 -KTYTVSVDED-ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVS 210 + YT V E + ++ + ++ATD D G N+A Y++ +F IDS +G + Sbjct: 550 PEGYTFEVQEGGVGLS----VGTVQATDRDSGINAATLYSLKSVADYSKFIIDSKTGVIK 605 Query: 211 LVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENV 270 +LD E + + A+D GSP S +++N+ D+ND+ P F + +V E Sbjct: 606 TSFSLDRETQDQLNIRVIARDTGSPQLSAEVGIIVNVTDINDHRPAFSQRQYSVTVQEK- 664 Query: 271 PIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA 330 + I+ + A D+D G+N+ L Y M D +GN T+D +G + T+G LDRE +A Sbjct: 665 RASHVILTLTATDSDRGINSALHY-MID---SGNFGNSFTLDALTGSLSTTGPLDREVRA 720 Query: 331 KYQLLVTATD-GGDP----PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 +Y LLV +D G+ P +A F QY + + ED PGT + Sbjct: 721 EYTLLVFVSDLQGNASLGIPLRDSAVVNVFIEDMNDNSPVFPQSQYSLTIPEDTAPGTGI 780 Query: 386 VTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443 + + A D D LHY I GN+ GRF I S + R + V PLD R Sbjct: 781 IQVQARDIDSGISQNLHYSIVSGNSLGRFFIDSSSAR--VYVKSPLDRDPPR-------- 830 Query: 444 TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503 + G + T V I I+D N+ P F A Y+ + E+ +GT VL S D D+G N Q Sbjct: 831 -NEG--AYTLEVTITISDVNDSPPEFSQAMYSVRIPENITLGTVVLQPSCVDRDLGTNGQ 887 Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET-MSGYLLTVTARDGGVPSLS 562 I+Y +SS S +F +NP +GA++ + D +T Y L +TA D G P+LS Sbjct: 888 ISYHISSGNSET-----PPRFSVNPSSGALSVSTEFDFDTGRKSYSLVLTATDKGEPALS 942 Score = 151 bits (365), Expect = 4e-34 Identities = 108/342 (31%), Positives = 173/342 (50%), Gaps = 44/342 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NV D NDH P F +QY +V+E +S +LTL ATD D G N+ + Y I+ Sbjct: 640 VNVTDINDHRPAFSQRQYSVTVQEKRASHV-ILTLTATDSDRGINSALHYMID------- 691 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS--D 128 + F +D +G+L T LDRE A YT+LV +D S Sbjct: 692 ------------SGNFGNSFTLDALTGSLSTTGPLDREVRAEYTLLVFVSDLQGNASLGI 739 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 L +A ++V I D NDN P F + Y++++ ED I +++A D D G + + Sbjct: 740 PLRDSAVVNVFIEDMNDNSPVFPQSQYSLTIPED--TAPGTGIIQVQARDIDSGISQNLH 797 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y+I+ GN+ +F IDS S V + LD + R+ +G + T ++ I I Sbjct: 798 YSIVSGNSLGRFFIDSSSARVYVKSPLDRDPPRN--------EG-----AYTLEVTITIS 844 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 DVND+ P F +++ + EN+ +G +++ D D G N +++Y ++ +GN + P Sbjct: 845 DVNDSPPEFSQAMYSVRIPENITLGTVVLQPSCVDRDLGTNGQISYHIS----SGNSETP 900 Query: 309 --ITIDPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDPPRS 347 +++P SG + S + D +T K Y L++TATD G+P S Sbjct: 901 PRFSVNPSSGALSVSTEFDFDTGRKSYSLVLTATDKGEPALS 942 Score = 123 bits (296), Expect = 8e-26 Identities = 130/421 (30%), Positives = 184/421 (43%), Gaps = 53/421 (12%) Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523 N P F Y + E+ P GT VL V A D++ N QITY LS E D + Sbjct: 24 NSPPRFVETQYVGRLPENQPTGTGVLTVRAVDNE---NDQITYQLSGE---------DGR 71 Query: 524 FVINPQTGAITTNKLLDRETMSGYLL------TVTARDGGVPSLSDTTDVEISVVDVNDN 577 F IN TG IT+N +DRE + G L A+ G D V + + DVNDN Sbjct: 72 FKINSVTGEITSNVNIDREKLPGSNLLEFKAIAYDAKGAGYDYRVDVP-VRVQIEDVNDN 130 Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637 PVF Y+ ++ E+ L GT+ V ATDAD G N I Y + + E F I G Sbjct: 131 TPVFINTPYSISVKENTL-GTTGFAVKATDADQGQNALIKYSITGGN-EANMFKIGAYEG 188 Query: 638 VIRT---NKALDRESVATHDLKAVAIDGGTPPQSSTVI--VHIKIEDINDSPPVFESDCL 692 I + LD E + +L A D G S T + V I++ED++D P VF D Sbjct: 189 TISVFPDSGVLDYEKYKSFNLTVSASDLGGVNGSRTAVTSVFIRVEDVDDLPAVFSPDYY 248 Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752 T ++E+S G + + A D D N V Y I G ++ E S KA + T+ Sbjct: 249 TAKVAESSTKGFYVTTVTARDGDLSLNKPVSYFIDQGITTSPQHYEPVSSSIKA-ISTI- 306 Query: 753 DLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG- 811 ++ V V+I +TD+NDNAP + + P G Sbjct: 307 ----------HKAVF----------ATVQITITDINDNAPKFVNLP-YSGTVPENSPTGL 345 Query: 812 PFGRVPAYDADVTDKLQYRI-LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVT 870 RV A DAD D ++ L+G ++ +E G + +S ++ +VSV+ Sbjct: 346 TVLRVTAQDADSGDNAKFTYSLTGAAGKFVVSSE--GYVVVSGNIDRETQDTYEFKVSVS 403 Query: 871 D 871 D Sbjct: 404 D 404 Score = 95.1 bits (226), Expect = 2e-17 Identities = 69/210 (32%), Positives = 111/210 (52%), Gaps = 15/210 (7%) Query: 567 VEISVVDVNDNEPV-FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625 +E +++ N P F + Y + E+ GT V V A D + N +I Y+L +D Sbjct: 14 IEAALIQGQANSPPRFVETQYVGRLPENQPTGTGVLTVRAVDNE---NDQITYQLSGED- 69 Query: 626 EEGSFVIDPASGVIRTNKALDRESVATHDL---KAVAID--GGTPPQSSTVIVHIKIEDI 680 G F I+ +G I +N +DRE + +L KA+A D G V V ++IED+ Sbjct: 70 --GRFKINSVTGEITSNVNIDREKLPGSNLLEFKAIAYDAKGAGYDYRVDVPVRVQIEDV 127 Query: 681 NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR 740 ND+ PVF + + + EN+ +GTT ++A D D+G NA++ YSI GG+++N F + Sbjct: 128 NDNTPVFINTPYSISVKENT-LGTTGFAVKATDADQGQNALIKYSITGGNEANMFKIGAY 186 Query: 741 QGSDKAELVTMVDLDYESPRKKYELVIRAA 770 +G+ + V LDYE K + L + A+ Sbjct: 187 EGTISVFPDSGV-LDYEK-YKSFNLTVSAS 214 Score = 84.2 bits (199), Expect = 5e-14 Identities = 70/243 (28%), Positives = 115/243 (47%), Gaps = 42/243 (17%) Query: 1 MSVPFCIHQQINVL--DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEV 58 + +P +NV D ND+SPVF QY ++ E + GT ++ ++A D D G + + Sbjct: 737 LGIPLRDSAVVNVFIEDMNDNSPVFPQSQYSLTIPEDTAPGTGIIQVQARDIDSGISQNL 796 Query: 59 EYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVK 118 Y+I V+ ++L F ID S + ++ LDR+ Sbjct: 797 HYSI--VSGNSLGR-----------------FFIDSSSARVYVKSPLDRD---------- 827 Query: 119 ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178 P + + T + + I D ND+ P+FS+ Y+V + E+I++ V+ + D Sbjct: 828 ------PPRNEGAYTLEVTITISDVNDSPPEFSQAMYSVRIPENITL--GTVVLQPSCVD 879 Query: 179 ADVGANSAIRYAIIGGN--TQMQFSIDSLSGDVSLVKTLDYEQVR-SYRLVIRAQDGGSP 235 D+G N I Y I GN T +FS++ SG +S+ D++ R SY LV+ A D G P Sbjct: 880 RDLGTNGQISYHISSGNSETPPRFSVNPSSGALSVSTEFDFDTGRKSYSLVLTATDKGEP 939 Query: 236 SRS 238 + S Sbjct: 940 ALS 942 >UniRef50_UPI0000660C02 Cluster: Homolog of Brachydanio rerio "Protocadherin2-gamma-v12-A.; n=1; Takifugu rubripes|Rep: Homolog of Brachydanio rerio "Protocadherin2-gamma-v12-A. - Takifugu rubripes Length = 1441 Score = 273 bits (670), Expect = 4e-71 Identities = 253/944 (26%), Positives = 415/944 (43%), Gaps = 99/944 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND++PVF+ ++ + E A G+ + KA D DIG N YT L Sbjct: 93 VEITDINDNAPVFQKEEKRFEISESAIVGSKFMLEKAIDPDIGMNGLQRYT--------L 144 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 P D DG + ++ + LDREK ++L+ A D P + Sbjct: 145 KPSDNFVLKLHTES--------DGDKKVEMILQKPLDREKQEHISLLLTAEDGGEP---Q 193 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 ++ T I+V ++D NDN P F++ Y ++ E+ +I K+ A+DAD G++ + Y Sbjct: 194 MTGTMRIYVAVLDVNDNAPVFTKPVYKANIAEN--AVRGTLITKVSASDADKGSHGEVSY 251 Query: 190 AIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 I F ++S GDV L +DYE+ + Y + + A D G S++++++I++ Sbjct: 252 VIANSMDPASNLFHVNS-EGDVILNGPIDYEREKHYDIDVEAIDSGG--LSDSSKIIIDV 308 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 DVNDN P SV+E+ + I + D D N ++ + N ++ Sbjct: 309 IDVNDNKPTINIISASGSVTEDSALKTVIALMSVNDPDSENNGKVQCMI-------NENI 361 Query: 308 PITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 P I S VY T +LDRE +++Y + V+ +D G P S++ T Sbjct: 362 PFEIKFTSNNVYSLLTERELDRERESEYNITVSCSDEGVPSLSSSVTLTLQISDVNDNPP 421 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRG---RFSITSQNG 419 F YE + E+ PG V T+ A D D ++ R+ Y + + G ++ Sbjct: 422 VFERSSYEAYIVENNTPGLSVFTVKARDTDWNQNARVSYILEDSSVNGVPVSSYVSVSAD 481 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAP---------- 467 G++ + D++Q + + V A D G S V+I I D N+ P Sbjct: 482 SGVVHAVRSFDYEQIKDFHFLVKAQDGGSPPLSSNVSVKILIQDQNDNPPQVLYPVQTGG 541 Query: 468 --VFENAPYTASV----FEDAPIGTTVLVVSATDSDVGINAQIT----------YSLSSE 511 V E P +A V ED +G L D +I L+ Sbjct: 542 SMVAEMVPRSADVGYLSAEDPDVGINALKAYTISKDDCFTLKIKEIENGRKVPELVLNKS 601 Query: 512 ISNEAVAHHDQQFVI----NP-QTG-AITTNKLLDRETMSGYLLT-VTARDGGVPSLSDT 564 + E A H NP ++G A T K+LD + T + A+D G P + Sbjct: 602 LDREKKAIHSLFLTAVDGGNPVKSGTAKITVKVLDVNDQCSRIRTYIFAKDKGHPQMEGH 661 Query: 565 TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624 V+I V+D+NDN P I EDA G+ V+ + A D D G NG++ L PKD Sbjct: 662 CRVQIMVIDINDNAPEIILTSVPNPIREDAQRGSVVALIRARDEDSGNNGKVMLHL-PKD 720 Query: 625 REEGSFVIDPASG---VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681 F + P+ G + T+ LDRE+++ ++++ A D G+PP SS I+ + I D+N Sbjct: 721 ---SPFTLKPSFGNNYALVTSGVLDRETISEYNIEITATDSGSPPLSSKKIIPVSITDVN 777 Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN-SFSLETR 740 D+PPVF Y+ EN G+ + + A D D G NA + YSI + S S Sbjct: 778 DNPPVFTQPSYNVYLKENGVPGSILYSVSASDLDFGENAKISYSILDSKVQDVSVSSYVY 837 Query: 741 QGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP--VMK 795 SD + +M DYE K +++ ++A SP L ++ V + + D NDNAP + Sbjct: 838 INSDNGSIYSMHSFDYEK-LKVFQIRVQAKDQGSPSLSSNTTVHVFILDQNDNAPAVIYP 896 Query: 796 DFQIIFNNYKDCFPVGP-----FGRVPAYDADVTDK--LQYRILSGNNANLILLNETTGS 848 + + P +V A DAD + YR+ +A+L +N+ TG Sbjct: 897 SSAALGSLSHQRMPRSAKAGHLLTKVTAVDADSGHNAWISYRLAEATDASLFTVNQYTGE 956 Query: 849 MTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEML 892 + ++ + + + D I++ ++V ++ E+ L Sbjct: 957 VRTKRAVSEQDDSSQRLLIEIKDDGEPIQS-STVTVSVLLEDGL 999 Score = 241 bits (589), Expect = 3e-61 Identities = 227/792 (28%), Positives = 352/792 (44%), Gaps = 78/792 (9%) Query: 97 GALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT 156 GALL + +DRE + R T Q + + + V I D NDN P F ++ Sbjct: 54 GALLVKEKIDREALCRQTTPCALHFQVT--LENPLELFPVTVEITDINDNAPVFQKEEKR 111 Query: 157 VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII-GGNTQMQFSIDSLSGD----VSL 211 + E V ++ K A D D+G N RY + N ++ +S GD + L Sbjct: 112 FEISESAIVGSKFMLEK--AIDPDIGMNGLQRYTLKPSDNFVLKLHTES-DGDKKVEMIL 168 Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271 K LD E+ L++ A+DGG P + T ++ + + DVNDNAP F +++ +++EN Sbjct: 169 QKPLDREKQEHISLLLTAEDGGEPQMTGTMRIYVAVLDVNDNAPVFTKPVYKANIAENAV 228 Query: 272 IGYSIVRVQAYDADEGVNAELTYTMTDK-DYTGNVDLPITIDPRSGWVYTSGQLDRETQA 330 G I +V A DAD+G + E++Y + + D N+ ++ G V +G +D E + Sbjct: 229 RGTLITKVSASDADKGSHGEVSYVIANSMDPASNL---FHVN-SEGDVILNGPIDYEREK 284 Query: 331 KYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTA 390 Y + V A D G S+ + V ED T + ++ Sbjct: 285 HYDIDVEAIDSGGLSDSSKIIIDVIDVNDNKPTINIISASGSV--TEDSALKTVIALMSV 342 Query: 391 TDADEDNRLHYE-ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG-- 447 D D +N + + N TS N L+T + LD ++E Y +TVS +D G Sbjct: 343 NDPDSENNGKVQCMINENIPFEIKFTSNNVYSLLT-ERELDRERESEYNITVSCSDEGVP 401 Query: 448 GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507 S + + + I+D N+ PVFE + Y A + E+ G +V V A D+D NA+++Y Sbjct: 402 SLSSSVTLTLQISDVNDNPPVFERSSYEAYIVENNTPGLSVFTVKARDTDWNQNARVSYI 461 Query: 508 L-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566 L S ++ V+ + ++ +G + + D E + + V A+DGG P LS Sbjct: 462 LEDSSVNGVPVSSY---VSVSADSGVVHAVRSFDYEQIKDFHFLVKAQDGGSPPLSSNVS 518 Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALVGTS--VSQVGATDADVGLNGRIHYELDPKD 624 V+I + D NDN P + T M +V S V + A D DVG+N Y + D Sbjct: 519 VKILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYLSAEDPDVGINALKAYTISKDD 578 Query: 625 REEGSF-VIDPASGV--IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681 I+ V + NK+LDRE A H L A+DGG P +S T + +K+ D+N Sbjct: 579 CFTLKIKEIENGRKVPELVLNKSLDREKKAIHSLFLTAVDGGNPVKSGTAKITVKVLDVN 638 Query: 682 D--------------SPPVFESDC----LTFYISENSP----------------IGTTIG 707 D P E C + I++N+P G+ + Sbjct: 639 DQCSRIRTYIFAKDKGHPQMEGHCRVQIMVIDINDNAPEIILTSVPNPIREDAQRGSVVA 698 Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 IRA D D G N V + + F+L+ G++ A LVT LD E+ +Y + I Sbjct: 699 LIRARDEDSGNNGKVMLHL---PKDSPFTLKPSFGNNYA-LVTSGVLDRET-ISEYNIEI 753 Query: 768 RA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY--KDCFPVGPFGRVPAYDAD 822 A SPPL + + + +TDVNDN PV Q +N Y ++ P V A D D Sbjct: 754 TATDSGSPPLSSKKIIPVSITDVNDNPPVFT--QPSYNVYLKENGVPGSILYSVSASDLD 811 Query: 823 VTD--KLQYRIL 832 + K+ Y IL Sbjct: 812 FGENAKISYSIL 823 Score = 173 bits (422), Expect = 4e-41 Identities = 172/620 (27%), Positives = 265/620 (42%), Gaps = 77/620 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND+ PVFE YEA + E + G +V T+KA D D +NA V Y +E + + + Sbjct: 411 LQISDVNDNPPVFERSSYEAYIVENNTPGLSVFTVKARDTDWNQNARVSYILEDSSVNGV 470 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 V + SG + S D E++ + LVKA D SP L Sbjct: 471 P--------------VSSYVSVSADSGVVHAVRSFDYEQIKDFHFLVKAQDGGSPP---L 513 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SS ++ + I D NDN PQ T V + + + A D DVG N+ Y Sbjct: 514 SSNVSVKILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYLSAEDPDVGINALKAYT 573 Query: 191 IIGGNTQMQFSIDSLSG-----DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 I + I + ++ L K+LD E+ + L + A DGG+P +S T ++ + Sbjct: 574 ISKDDC-FTLKIKEIENGRKVPELVLNKSLDREKKAIHSLFLTAVDGGNPVKSGTAKITV 632 Query: 246 NIRDVNDNAPRFYTSLFQES------------------VSENVP--IGYSIVRVQAYDAD 285 + DVND R T +F + +++N P I S+ DA Sbjct: 633 KVLDVNDQCSRIRTYIFAKDKGHPQMEGHCRVQIMVIDINDNAPEIILTSVPNPIREDAQ 692 Query: 286 EG-VNAELTYTMTDKDYTGNV------DLPITIDPRSGWVY---TSGQLDRETQAKYQLL 335 G V A + D G V D P T+ P G Y TSG LDRET ++Y + Sbjct: 693 RGSVVALIRARDEDSGNNGKVMLHLPKDSPFTLKPSFGNNYALVTSGVLDRETISEYNIE 752 Query: 336 VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD- 394 +TATD G PP S+ F Y V L E+ PG+ + +++A+D D Sbjct: 753 ITATDSGSPPLSSKKIIPVSITDVNDNPPVFTQPSYNVYLKENGVPGSILYSVSASDLDF 812 Query: 395 -EDNRLHYEITGGNTRGRFSITS----QNGRGLITVAQPLDFKQERRYVLTVSATDSG-- 447 E+ ++ Y I + S++S + G I D+++ + + + V A D G Sbjct: 813 GENAKISYSILDSKVQD-VSVSSYVYINSDNGSIYSMHSFDYEKLKVFQIRVQAKDQGSP 871 Query: 448 GRSDTAMVQINITDANNYAP--VFENAPYTASVF-----EDAPIGTTVLVVSATDSDVGI 500 S V + I D N+ AP ++ ++ S+ A G + V+A D+D G Sbjct: 872 SLSSNTTVHVFILDQNDNAPAVIYPSSAALGSLSHQRMPRSAKAGHLLTKVTAVDADSGH 931 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560 NA I+Y L A A F +N TG + T + + + S L + +D G P Sbjct: 932 NAWISYRL-------AEATDASLFTVNQYTGEVRTKRAVSEQDDSSQRLLIEIKDDGEPI 984 Query: 561 LSDTTDVEISVVDVNDNEPV 580 S T V + + D +EP+ Sbjct: 985 QSSTVTVSVLLED-GLHEPI 1003 Score = 147 bits (355), Expect = 6e-33 Identities = 106/354 (29%), Positives = 176/354 (49%), Gaps = 40/354 (11%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 QI V+D ND++P + +RE A G+ V ++A D+D G N +V + + T Sbjct: 665 QIMVIDINDNAPEIILTSVPNPIREDAQRGSVVALIRARDEDSGNNGKVMLHLPKDSPFT 724 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L P G + AL+T LDRE ++ Y + + ATD SP Sbjct: 725 LKPS-------------------FGNNYALVTSGVLDRETISEYNIEITATDSGSP---P 762 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LSS I V+I D NDN P F++ +Y V + E + ++ + A+D D G N+ I Y Sbjct: 763 LSSKKIIPVSITDVNDNPPVFTQPSYNVYLKE--NGVPGSILYSVSASDLDFGENAKISY 820 Query: 190 AIIGGNTQ-----MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 +I+ Q I+S +G + + + DYE+++ +++ ++A+D GSPS S+ T + Sbjct: 821 SILDSKVQDVSVSSYVYINSDNGSIYSMHSFDYEKLKVFQIRVQAKDQGSPSLSSNTTVH 880 Query: 245 INIRDVNDNAPR-FYT------SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297 + I D NDNAP Y SL + + + G+ + +V A DAD G NA ++Y + Sbjct: 881 VFILDQNDNAPAVIYPSSAALGSLSHQRMPRSAKAGHLLTKVTAVDADSGHNAWISYRLA 940 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 + + L T++ +G V T + + + +LL+ D G+P +S+T T Sbjct: 941 E---ATDASL-FTVNQYTGEVRTKRAVSEQDDSSQRLLIEIKDDGEPIQSSTVT 990 Score = 113 bits (273), Expect = 5e-23 Identities = 77/248 (31%), Positives = 120/248 (48%), Gaps = 11/248 (4%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F +D G L+ +DRE + + T Q V++ I V I D NDNYP Sbjct: 1200 FSVDAGKGELVVNDRIDREALCGQSASCVLTLQV--VTENPLQLHRIEVEIKDINDNYPN 1257 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD- 208 F + + E + ++ A D DVG+NS Y + + + LSGD Sbjct: 1258 FLTGERFLKIAESTAAGVRFLLET--AQDPDVGSNSVKSYTL-SKDECFSLKMKDLSGDR 1314 Query: 209 ----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 + L KTLD E+ S+ L++ A DGG+P ++ TT +++ + D NDN P F L+ Sbjct: 1315 QIPELVLDKTLDREKQDSHHLLLTAIDGGNPVKTGTTTIIVTVLDNNDNVPVFQKPLYNI 1374 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 S+ EN +++V+A DADEGVN E+ Y+ + + + +D +G ++ GQL Sbjct: 1375 SLPENSSTSSVLLKVEATDADEGVNGEIEYSFPEHTPQDILSV-FRLDSSTGEIFLVGQL 1433 Query: 325 DRETQAKY 332 D E Y Sbjct: 1434 DYEKSIMY 1441 Score = 99.1 bits (236), Expect = 2e-18 Identities = 62/196 (31%), Positives = 100/196 (51%), Gaps = 5/196 (2%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 +++ I D N+ P F + E G L+ +A D DVG N+ +Y+LS + Sbjct: 1244 IEVEIKDINDNYPNFLTGERFLKIAESTAAGVRFLLETAQDPDVGSNSVKSYTLSKD--- 1300 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 E + + + Q + +K LDRE + L +TA DGG P + TT + ++V+D Sbjct: 1301 ECFSLKMKDLSGDRQIPELVLDKTLDREKQDSHHLLLTAIDGGNPVKTGTTTIIVTVLDN 1360 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE--GSFVI 632 NDN PVF++ LY ++ E++ + + +V ATDAD G+NG I Y ++ F + Sbjct: 1361 NDNVPVFQKPLYNISLPENSSTSSVLLKVEATDADEGVNGEIEYSFPEHTPQDILSVFRL 1420 Query: 633 DPASGVIRTNKALDRE 648 D ++G I LD E Sbjct: 1421 DSSTGEIFLVGQLDYE 1436 Score = 96.7 bits (230), Expect = 8e-18 Identities = 78/274 (28%), Positives = 115/274 (41%), Gaps = 12/274 (4%) Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 VV D+G+ + ++ EA Q F ++ G + N +DRE + G Sbjct: 1169 VVGNLAKDLGLGLSDIFDRKLRVAAEA---GKQYFSVDAGKGELVVNDRIDREALCGQSA 1225 Query: 550 T-VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 + V + +E+ + D+NDN P F I E G A D Sbjct: 1226 SCVLTLQVVTENPLQLHRIEVEIKDINDNYPNFLTGERFLKIAESTAAGVRFLLETAQDP 1285 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASG-----VIRTNKALDRESVATHDLKAVAIDGG 663 DVG N Y L KD E S + SG + +K LDRE +H L AIDGG Sbjct: 1286 DVGSNSVKSYTLS-KD-ECFSLKMKDLSGDRQIPELVLDKTLDREKQDSHHLLLTAIDGG 1343 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 P ++ T + + + D ND+ PVF+ + ENS + + ++ A D DEG N + Sbjct: 1344 NPVKTGTTTIIVTVLDNNDNVPVFQKPLYNISLPENSSTSSVLLKVEATDADEGVNGEIE 1403 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757 YS + S+ R S E+ + LDYE Sbjct: 1404 YSFPEHTPQDILSV-FRLDSSTGEIFLVGQLDYE 1436 Score = 75.8 bits (178), Expect = 2e-11 Identities = 59/243 (24%), Positives = 108/243 (44%), Gaps = 6/243 (2%) Query: 200 FSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF 257 FS+D+ G++ + +D E + +S V+ Q + + ++ + I+D+NDN P F Sbjct: 1200 FSVDAGKGELVVNDRIDREALCGQSASCVLTLQVV-TENPLQLHRIEVEIKDINDNYPNF 1258 Query: 258 YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317 T ++E+ G + A D D G N+ +YT++ + ++ D + Sbjct: 1259 LTGERFLKIAESTAAGVRFLLETAQDPDVGSNSVKSYTLSKDECFSLKMKDLSGDRQIPE 1318 Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377 + LDRE Q + LL+TA DGG+P ++ T T F Y + L E Sbjct: 1319 LVLDKTLDREKQDSHHLLLTAIDGGNPVKTGTTTIIVTVLDNNDNVPVFQKPLYNISLPE 1378 Query: 378 DEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSI-TSQNGRGLITVAQPLDFKQE 434 + + ++ + ATDADE + + Y + S+ + G I + LD+++ Sbjct: 1379 NSSTSSVLLKVEATDADEGVNGEIEYSFPEHTPQDILSVFRLDSSTGEIFLVGQLDYEKS 1438 Query: 435 RRY 437 Y Sbjct: 1439 IMY 1441 Score = 56.4 bits (130), Expect = 1e-05 Identities = 46/184 (25%), Positives = 85/184 (46%), Gaps = 12/184 (6%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG---- 421 F+ G+ +++AE G + TA D D + T FS+ ++ G Sbjct: 1258 FLTGERFLKIAESTAAGVRFLLETAQDPDVGSNSVKSYTLSKDEC-FSLKMKDLSGDRQI 1316 Query: 422 -LITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASV 478 + + + LD +++ + L ++A D G ++ T + + + D N+ PVF+ Y S+ Sbjct: 1317 PELVLDKTLDREKQDSHHLLLTAIDGGNPVKTGTTTIIVTVLDNNDNVPVFQKPLYNISL 1376 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 E++ + +L V ATD+D G+N +I YS + ++ F ++ TG I Sbjct: 1377 PENSSTSSVLLKVEATDADEGVNGEIEYSFPEHTPQDILS----VFRLDSSTGEIFLVGQ 1432 Query: 539 LDRE 542 LD E Sbjct: 1433 LDYE 1436 Score = 54.8 bits (126), Expect = 3e-05 Identities = 35/103 (33%), Positives = 52/103 (50%), Gaps = 16/103 (15%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND+ PVF+ Y S+ E +S+ + +L ++ATD D G N E+EY+ T Sbjct: 1355 VTVLDNNDNVPVFQKPLYNISLPENSSTSSVLLKVEATDADEGVNGEIEYSFPEHT---- 1410 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARY 113 P+D + VFR+D +G + LD EK Y Sbjct: 1411 -PQD-----------ILSVFRLDSSTGEIFLVGQLDYEKSIMY 1441 >UniRef50_UPI0000E4A946 Cluster: PREDICTED: similar to cadherin 23; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to cadherin 23 - Strongylocentrotus purpuratus Length = 1482 Score = 272 bits (668), Expect = 7e-71 Identities = 266/904 (29%), Positives = 414/904 (45%), Gaps = 108/904 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + + ND++PVF QY+ S+ E + T V L+ATD D+G E T EL+ + Sbjct: 325 VYLTNINDNTPVFSQSQYDVSLPENSVENTPVQQLEATDADVG----AELTFELLGYNN- 379 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSG--ALLTRASLDREKVARYTVLVKATDQASPVSD 128 D F I+ +G ++ A + E ++ Y + +D + Sbjct: 380 -----------------DWFNINSSTGYISVSDTADFNAELLSVYFLTCVVSD-----GE 417 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE-DISVTDNPV----IAKIKATDADVGA 183 R+S TA ++V + D NDN P F Y+VS+ E ++ + + I ++ ATDAD+ Sbjct: 418 RVS-TALLNVTVTDVNDNPPLFQLDLYSVSIPEYNVDMLEEEDEGLNILQVLATDADINV 476 Query: 184 -NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYE-QVRSYRLVIRAQDGGSPSRSNTT 241 N + Y+I GN + +F I+S +G + ++D E + ++ +V+ A DGG+PS + TT Sbjct: 477 INRMLTYSIESGNEEGKFDINSTTGMIFRKASIDRETEEATFEMVVMAIDGGTPSMNGTT 536 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 + I+I DVNDN P F +L+ V EN G + + A D D + ++ YT+ + Sbjct: 537 LVTISIEDVNDNNPIFLAALYNAEVPENAAFGTLVANITAVDMDVD-SLDVLYTIEEAS- 594 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 P ++ + G + SG +D E Q Y L VTATD D R + T Sbjct: 595 ------PFLVN-QEGLITLSGTVDYEIQMTYNLTVTATDREDTSRQGSCTVMINIMDVND 647 Query: 362 XXXXF-MPGQYEVELAE-----DEPPGTP----VVTLTATDADEDNRLHYEITG------ 405 F P + + E D PG+ ++TL ATD D + L Y I Sbjct: 648 EPPEFDTPSPSSLSVNESAAYCDSLPGSDDCHVLITLQATDPDTNTDLRYSILDVKGYDE 707 Query: 406 ------GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD------SGGRSDTA 453 GN +F + S+ G + V LD + +R+ +TV D + ++D+A Sbjct: 708 NSRLVVGNFSDQFGVDSETGD--VFVRTELDRETVQRFDVTVVVDDMKAEENNDTQTDSA 765 Query: 454 MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV-VSATDSDVGINAQITYSLSSEI 512 + I + D N+ AP F + P + E +G + V + A D D N + Y L + Sbjct: 766 ELVITVLDVNDNAPEFIDLPDNFTTPETDQVGMVISVNILADDEDAEDNGIVIYELLDDA 825 Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572 VA I+ TG +T + +D+E +T A+DGG P L+ T +I + Sbjct: 826 GG-LVA-------ISETTGILTVKQPIDKELNDSLTITFCAKDGGDPPLNTTVTRQIFIT 877 Query: 573 DVNDNEPVFKQQL-YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631 DVNDN PVF L A+I+ED GT V V ATDAD G + Y + E FV Sbjct: 878 DVNDNTPVFNVSLPNEASILEDTTNGTLVLTVYATDADPDF-GDLTYTISAGVGLE-DFV 935 Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF-ESD 690 I+P +G I LDRE A + L VA DG + + V I I D+ND+ P F ES Sbjct: 936 INPENGDITVQNELDREEQALYTLTVVASDG---IRQDNLEVTITILDVNDNHPEFTESF 992 Query: 691 CLTFYISENSPIGTTIGEIRAHDPDE--GPNAVVHYSIKGGDDSNSFSLETRQGSDKAEL 748 + ISE + G+++ I A D DE N+ V Y + + S F ++ G + Sbjct: 993 PESTTISETAEPGSSVAAIVAVDDDEPGTNNSAVRYIMTDENQSGFFKMDYVTG---VVI 1049 Query: 749 VTMVDLDYESPRKKYELVIRAA---SPPLWNDVR-VEILVTDVNDNAPVMKDFQIIFNNY 804 + D P Y LV+ A+ PPL D R ++VTD ND APV + Y Sbjct: 1050 LNTTSTDALIP-GVYVLVVVASDLGDPPLMTDPRNFSVIVTDYNDEAPVFVQPKQGATVY 1108 Query: 805 KDCFPVGPFGRVPAYDADVTDK--LQYRILSGNNA----NLILLNETTGSMTLSPQLNTN 858 D G A D D+ D + + +G A ++ETTG++ ++ + + Sbjct: 1109 VDENYSGHITTAEATDGDLGDNGVVTFAFDTGLGATDDYKYFTIDETTGAIEITSETDRE 1168 Query: 859 VPKL 862 ++ Sbjct: 1169 TKEI 1172 Score = 254 bits (622), Expect = 3e-65 Identities = 247/819 (30%), Positives = 386/819 (47%), Gaps = 82/819 (10%) Query: 11 INVLDCNDHSPVFEMQQY-EASVREGASSGTTV-LTLKATDQDIGKNAEVEYTIELVTAD 68 I + D +D+ P F + A++ E + GT + +L+A D D G+ + ++E Sbjct: 213 IRLSDVDDNPPTFTPKGVVNATIPEHSPRGTQLDFSLEAFDLDSGEAGRIILSLEDDEGI 272 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 + V DV R+D S +LD E+++ T +KA+D + Sbjct: 273 FYLVSETIFNSG-----VVDV-RVDNSS-------ALDFERISEVTFQIKASDAQG--GN 317 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 TAT+++ I NDN P FS+ Y VS+ E+ SV + PV +++ATDADVGA + Sbjct: 318 FSVVTATVYLTNI--NDNTPVFSQSQYDVSLPEN-SVENTPV-QQLEATDADVGAE--LT 371 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDY--EQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 + ++G N F+I+S +G +S+ T D+ E + Y L DG R +T L + Sbjct: 372 FELLGYNNDW-FNINSSTGYISVSDTADFNAELLSVYFLTCVVSDG---ERVSTALLNVT 427 Query: 247 IRDVNDNAPRFYTSLFQESVSE-NVPI------GYSIVRVQAYDADEGV-NAELTYTMTD 298 + DVNDN P F L+ S+ E NV + G +I++V A DAD V N LTY++ Sbjct: 428 VTDVNDNPPLFQLDLYSVSIPEYNVDMLEEEDEGLNILQVLATDADINVINRMLTYSIE- 486 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRET-QAKYQLLVTATDGGDPPRSATATXXXXXX 357 +GN + I+ +G ++ +DRET +A ++++V A DGG P + T Sbjct: 487 ---SGNEEGKFDINSTTGMIFRKASIDRETEEATFEMVVMAIDGGTPSMNGTTLVTISIE 543 Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN-RLHYEITGGNTRGRFSITS 416 F+ Y E+ E+ GT V +TA D D D+ + Y I + F + Sbjct: 544 DVNDNNPIFLAALYNAEVPENAAFGTLVANITAVDMDVDSLDVLYTIEEASP---FLV-- 598 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATD--SGGRSDTAMVQINITDANNYAPVFEN-AP 473 N GLIT++ +D++ + Y LTV+ATD R + V INI D N+ P F+ +P Sbjct: 599 -NQEGLITLSGTVDYEIQMTYNLTVTATDREDTSRQGSCTVMINIMDVNDEPPEFDTPSP 657 Query: 474 YTASVFEDAPI-----GT----TVLVVSATDSDVGINAQITYSL-----SSEISNEAVAH 519 + SV E A G+ ++ + ATD D N + YS+ E S V + Sbjct: 658 SSLSVNESAAYCDSLPGSDDCHVLITLQATDPDT--NTDLRYSILDVKGYDENSRLVVGN 715 Query: 520 HDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT----TDVEISVVDVN 575 QF ++ +TG + LDRET+ + +TV D +DT ++ I+V+DVN Sbjct: 716 FSDQFGVDSETGDVFVRTELDRETVQRFDVTVVVDDMKAEENNDTQTDSAELVITVLDVN 775 Query: 576 DNEPVFKQQLYTANIMEDALVGTSVS-QVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634 DN P F E VG +S + A D D NG + YEL D G I Sbjct: 776 DNAPEFIDLPDNFTTPETDQVGMVISVNILADDEDAEDNGIVIYEL--LDDAGGLVAISE 833 Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT- 693 +G++ + +D+E + + A DGG PP ++TV I I D+ND+ PVF Sbjct: 834 TTGILTVKQPIDKELNDSLTITFCAKDGGDPPLNTTVTRQIFITDVNDNTPVFNVSLPNE 893 Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753 I E++ GT + + A D D + Y+I G F + G ++ + Sbjct: 894 ASILEDTTNGTLVLTVYATDADPDFGDLT-YTISAGVGLEDFVINPENG----DITVQNE 948 Query: 754 LDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP 792 LD E + Y L + A+ +++ V I + DVNDN P Sbjct: 949 LDREE-QALYTLTVVASDGIRQDNLEVTITILDVNDNHP 986 Score = 233 bits (570), Expect = 5e-59 Identities = 239/848 (28%), Positives = 372/848 (43%), Gaps = 115/848 (13%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I++ D ND++P+F Y A V E A+ GT V + A D D+ + +V YTIE + + Sbjct: 540 ISIEDVNDNNPIFLAALYNAEVPENAAFGTLVANITAVDMDV-DSLDVLYTIEEASPFLV 598 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N E G + ++D E Y + V ATD+ + R Sbjct: 599 NQE-----------------------GLITLSGTVDYEIQMTYNLTVTATDRED--TSRQ 633 Query: 131 SSTATIHVNIIDDNDNYPQF-SEKTYTVSVDEDISVTDN-------PVIAKIKATDADVG 182 S T+ +NI+D ND P+F + ++SV+E + D+ V+ ++ATD D Sbjct: 634 GS-CTVMINIMDVNDEPPEFDTPSPSSLSVNESAAYCDSLPGSDDCHVLITLQATDPD-- 690 Query: 183 ANSAIRYAIIG------------GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ 230 N+ +RY+I+ GN QF +DS +GDV + LD E V+ + + + Sbjct: 691 TNTDLRYSILDVKGYDENSRLVVGNFSDQFGVDSETGDVFVRTELDRETVQRFDVTVVVD 750 Query: 231 D----GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSI-VRVQAYDAD 285 D + +++++ +L+I + DVNDNAP F + E +G I V + A D D Sbjct: 751 DMKAEENNDTQTDSAELVITVLDVNDNAPEFIDLPDNFTTPETDQVGMVISVNILADDED 810 Query: 286 EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP 345 N + Y + D G + + I +G + +D+E + A DGGDPP Sbjct: 811 AEDNGIVIYELLDD--AGGL---VAISETTGILTVKQPIDKELNDSLTITFCAKDGGDPP 865 Query: 346 RSATATXXXXXXXXXXXXXXF-MPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEI 403 + T T F + E + ED GT V+T+ ATDAD D L Y I Sbjct: 866 LNTTVTRQIFITDVNDNTPVFNVSLPNEASILEDTTNGTLVLTVYATDADPDFGDLTYTI 925 Query: 404 TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDAN 463 + G F I +NG ITV LD +++ Y LTV A+D G R D V I I D N Sbjct: 926 SAGVGLEDFVINPENGD--ITVQNELDREEQALYTLTVVASD-GIRQDNLEVTITILDVN 982 Query: 464 NYAPVF-ENAPYTASVFEDAPIGTTVLVVSATDSD-VGI-NAQITYSLSSEISNEAVAHH 520 + P F E+ P + ++ E A G++V + A D D G N+ + Y ++ E + Sbjct: 983 DNHPEFTESFPESTTISETAEPGSSVAAIVAVDDDEPGTNNSAVRYIMTDE-------NQ 1035 Query: 521 DQQFVINPQTGAITTNKLLDRETMSG-YLLTVTARD-GGVPSLSDTTDVEISVVDVNDNE 578 F ++ TG + N + G Y+L V A D G P ++D + + V D ND Sbjct: 1036 SGFFKMDYVTGVVILNTTSTDALIPGVYVLVVVASDLGDPPLMTDPRNFSVIVTDYNDEA 1095 Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP---KDREEGSFVIDPA 635 PVF Q A + D ++ ATD D+G NG + + D + F ID Sbjct: 1096 PVFVQPKQGATVYVDENYSGHITTAEATDGDLGDNGVVTFAFDTGLGATDDYKYFTIDET 1155 Query: 636 SGVIRTNKALDRESVATHDLKAVAIDG----GTPPQSSTVIVHIKIEDINDSPPVF---- 687 +G I DRE+ + + I G P +SS V ++++ D +D+ P + Sbjct: 1156 TGAIEITSETDRETKEIYIRLLLGIIGMNAKSDPIRSSQVTFYVQVNDTDDNEPAYWGER 1215 Query: 688 --------ESDCLTFYISENSPIGTTIGEI-RAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738 + Y+ EN GT +G + A D D ++Y I + F L+ Sbjct: 1216 TGPEGPQDPPEAALLYVQENLGEGTFVGTVPEAVDLDSDLYNQIYYFIVSATSEDYFILD 1275 Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW--------------NDVRVEILV 784 G+ +T+V+ R ++ LVI A S P + N RV + V Sbjct: 1276 KYSGN-----LTLVNPIDREKRPEFSLVIWADSNPDYEPDMNVIYDPLKEDNLARVTVTV 1330 Query: 785 TDVNDNAP 792 +DVND+ P Sbjct: 1331 SDVNDSPP 1338 Score = 213 bits (520), Expect = 6e-53 Identities = 215/764 (28%), Positives = 321/764 (42%), Gaps = 72/764 (9%) Query: 11 INVLDCNDHSPVFEMQQYEA-SVREGAS-----SGT----TVLTLKATDQDIGKNAEVEY 60 IN++D ND P F+ + SV E A+ G+ ++TL+ATD D N ++ Y Sbjct: 640 INIMDVNDEPPEFDTPSPSSLSVNESAAYCDSLPGSDDCHVLITLQATDPDT--NTDLRY 697 Query: 61 TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT 120 +I L+ + D F +D +G + R LDRE V R+ V V Sbjct: 698 SI-------LDVKGYDENSRLVVGNFSDQFGVDSETGDVFVRTELDRETVQRFDVTVVVD 750 Query: 121 D-QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA 179 D +A +D + +A + + ++D NDN P+F + + E V + I A D Sbjct: 751 DMKAEENNDTQTDSAELVITVLDVNDNAPEFIDLPDNFTTPETDQV-GMVISVNILADDE 809 Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239 D N + Y ++ + +I +G +++ + +D E S + A+DGG P + Sbjct: 810 DAEDNGIVIYELLDDAGGL-VAISETTGILTVKQPIDKELNDSLTITFCAKDGGDPPLNT 868 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQE-SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 T I I DVNDN P F SL E S+ E+ G ++ V A DAD +LTYT++ Sbjct: 869 TVTRQIFITDVNDNTPVFNVSLPNEASILEDTTNGTLVLTVYATDADPDFG-DLTYTISA 927 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG-GDPPRSATATXXXXXX 357 G D I+P +G + +LDRE QA Y L V A+DG T T Sbjct: 928 G--VGLEDF--VINPENGDITVQNELDREEQALYTLTVVASDGIRQDNLEVTITILDVND 983 Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE----DNRLHYEITGGNTRGRFS 413 F E AE PG+ V + A D DE ++ + Y +T N G F Sbjct: 984 NHPEFTESFPESTTISETAE---PGSSVAAIVAVDDDEPGTNNSAVRYIMTDENQSGFFK 1040 Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFE 470 + G ++ D YVL V A+D G +D + +TD N+ APVF Sbjct: 1041 MDYVTGVVILNTTST-DALIPGVYVLVVVASDLGDPPLMTDPRNFSVIVTDYNDEAPVFV 1099 Query: 471 NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 A+V+ D + ATD D+G N +T++ + + + F I+ T Sbjct: 1100 QPKQGATVYVDENYSGHITTAEATDGDLGDNGVVTFAFDTGLG---ATDDYKYFTIDETT 1156 Query: 531 GAITTNKLLDRETMSGYLLTVTARDG----GVPSLSDTTDVEISVVDVNDNEPVF----- 581 GAI DRET Y+ + G P S + V D +DNEP + Sbjct: 1157 GAIEITSETDRETKEIYIRLLLGIIGMNAKSDPIRSSQVTFYVQVNDTDDNEPAYWGERT 1216 Query: 582 -------KQQLYTANIMEDALVGTSVSQVG-ATDADVGLNGRIHYELDPKDREEGSFVID 633 + + E+ GT V V A D D L +I+Y + E+ F++D Sbjct: 1217 GPEGPQDPPEAALLYVQENLGEGTFVGTVPEAVDLDSDLYNQIYYFIVSATSED-YFILD 1275 Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI-----------VHIKIEDIND 682 SG + +DRE L A VI V + + D+ND Sbjct: 1276 KYSGNLTLVNPIDREKRPEFSLVIWADSNPDYEPDMNVIYDPLKEDNLARVTVTVSDVND 1335 Query: 683 SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 SPP FE D T + ++ G + + A DPD G NAV Y+I Sbjct: 1336 SPPRFEEDRYTAGVLYSTSFGVEVITVNAVDPDLGENAVTVYTI 1379 Score = 204 bits (499), Expect = 2e-50 Identities = 217/769 (28%), Positives = 350/769 (45%), Gaps = 79/769 (10%) Query: 155 YTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS-GDVSL-V 212 +T ++++ S++ N + A + + R+ G +Q +D LS G+V L V Sbjct: 121 FTSEIEDNGSISPNFGCGRYAAMTLTILPVNNGRFHSADGPSQRP--VDWLSTGEVVLTV 178 Query: 213 KTLDYEQVRSYRLVIRAQDGGSPSRS-NT-TQLLINIRDVNDNAPRFYTS-LFQESVSEN 269 D + + R I D P NT T + I + DV+DN P F + ++ E+ Sbjct: 179 VANDGDLGVNLRNAIEEDDDDQPMEQINTNTSIYIRLSDVDDNPPTFTPKGVVNATIPEH 238 Query: 270 VPIGYSI-VRVQAYDADEGVNAELTYTMTDKD-----YTGNVDLPITIDPRSGWVYTSGQ 323 P G + ++A+D D G + ++ D + + + +D R V S Sbjct: 239 SPRGTQLDFSLEAFDLDSGEAGRIILSLEDDEGIFYLVSETIFNSGVVDVR---VDNSSA 295 Query: 324 LDRE--TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381 LD E ++ +Q+ + GG+ + T F QY+V L E+ Sbjct: 296 LDFERISEVTFQIKASDAQGGN---FSVVTATVYLTNINDNTPVFSQSQYDVSLPENSVE 352 Query: 382 GTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR--YVL 439 TPV L ATDAD L +E+ G N F+I S G I+V+ DF E Y L Sbjct: 353 NTPVQQLEATDADVGAELTFELLGYNNDW-FNINSSTG--YISVSDTADFNAELLSVYFL 409 Query: 440 TVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASV-------FEDAPIGTTVLVVS 492 T +D G R TA++ + +TD N+ P+F+ Y+ S+ E+ G +L V Sbjct: 410 TCVVSD-GERVSTALLNVTVTDVNDNPPLFQLDLYSVSIPEYNVDMLEEEDEGLNILQVL 468 Query: 493 ATDSDVG-INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG-YLLT 550 ATD+D+ IN +TYS+ S NE + +F IN TG I +DRET + + Sbjct: 469 ATDADINVINRMLTYSIES--GNE-----EGKFDINSTTGMIFRKASIDRETEEATFEMV 521 Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610 V A DGG PS++ TT V IS+ DVNDN P+F LY A + E+A GT V+ + A D DV Sbjct: 522 VMAIDGGTPSMNGTTLVTISIEDVNDNNPIFLAALYNAEVPENAAFGTLVANITAVDMDV 581 Query: 611 GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST 670 + + Y ++ E F+++ G+I + +D E T++L A D + + Sbjct: 582 D-SLDVLYTIE----EASPFLVN-QEGLITLSGTVDYEIQMTYNLTVTATDREDTSRQGS 635 Query: 671 VIVHIKIEDINDSPPVFESDC-LTFYISENSPIGTTIG---------EIRAHDPDEGPNA 720 V I I D+ND PP F++ + ++E++ ++ ++A DPD N Sbjct: 636 CTVMINIMDVNDEPPEFDTPSPSSLSVNESAAYCDSLPGSDDCHVLITLQATDPD--TNT 693 Query: 721 VVHYSI---KGGDDSN-----SFSLETRQGSDKAELVTMVDLDYES-PRKKYELVIRAAS 771 + YSI KG D+++ +FS + S+ ++ +LD E+ R +V+ Sbjct: 694 DLRYSILDVKGYDENSRLVVGNFSDQFGVDSETGDVFVRTELDRETVQRFDVTVVVDDMK 753 Query: 772 PPLWNDVRVE-----ILVTDVNDNAPVMKDFQIIFNNYK-DCFPVGPFGRVPAYDADVTD 825 ND + + I V DVNDNAP D F + D + + A D D D Sbjct: 754 AEENNDTQTDSAELVITVLDVNDNAPEFIDLPDNFTTPETDQVGMVISVNILADDEDAED 813 Query: 826 K--LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 + Y +L + L+ ++ETTG +T+ ++ + T+ DG Sbjct: 814 NGIVIYELLD-DAGGLVAISETTGILTVKQPIDKELNDSLTITFCAKDG 861 Score = 180 bits (438), Expect = 5e-43 Identities = 220/812 (27%), Positives = 345/812 (42%), Gaps = 88/812 (10%) Query: 117 VKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKA 176 ++ D P+ +++++ +I++ + D +DN P F+ K + + S + ++A Sbjct: 193 IEEDDDDQPM-EQINTNTSIYIRLSDVDDNPPTFTPKGVVNATIPEHSPRGTQLDFSLEA 251 Query: 177 TDADVGANSAIRYAIIGGN------TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ 230 D D G I ++ ++ F+ + V LD+E++ I+A Sbjct: 252 FDLDSGEAGRIILSLEDDEGIFYLVSETIFNSGVVDVRVDNSSALDFERISEVTFQIKAS 311 Query: 231 D--GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV 288 D GG+ S T L NI NDN P F S + S+ EN + +++A DAD V Sbjct: 312 DAQGGNFSVVTATVYLTNI---NDNTPVFSQSQYDVSLPENSVENTPVQQLEATDAD--V 366 Query: 289 NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD--RETQAKYQLLVTATDGGDPPR 346 AELT+ + Y + I+ +G++ S D E + Y L +DG R Sbjct: 367 GAELTFELL--GYNNDW---FNINSSTGYISVSDTADFNAELLSVYFLTCVVSDG---ER 418 Query: 347 SATATXXXXXXXXXXXXXXFMPG-------QYEVELAEDEPPGTPVVTLTATDADED--N 397 +TA F +Y V++ E+E G ++ + ATDAD + N Sbjct: 419 VSTALLNVTVTDVNDNPPLFQLDLYSVSIPEYNVDMLEEEDEGLNILQVLATDADINVIN 478 Query: 398 R-LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK-QERRYVLTVSATDSG--GRSDTA 453 R L Y I GN G+F I S G+I +D + +E + + V A D G + T Sbjct: 479 RMLTYSIESGNEEGKFDINSTT--GMIFRKASIDRETEEATFEMVVMAIDGGTPSMNGTT 536 Query: 454 MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513 +V I+I D N+ P+F A Y A V E+A GT V ++A D DV + + Y++ Sbjct: 537 LVTISIEDVNDNNPIFLAALYNAEVPENAAFGTLVANITAVDMDVD-SLDVLYTI----- 590 Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 EA F++N Q G IT + +D E Y LTVTA D S + V I+++D Sbjct: 591 EEA-----SPFLVN-QEGLITLSGTVDYEIQMTYNLTVTATDREDTSRQGSCTVMINIMD 644 Query: 574 VNDNEPVFKQQLYTA-NIME-----DALVGTSVSQV----GATDADVGLNGRIHYELDPK 623 VND P F ++ ++ E D+L G+ V ATD D + R + LD K Sbjct: 645 VNDEPPEFDTPSPSSLSVNESAAYCDSLPGSDDCHVLITLQATDPDTNTDLR-YSILDVK 703 Query: 624 DREEGS----------FVIDPASGVIRTNKALDRESVATHDLKAVAID----GGTPPQSS 669 +E S F +D +G + LDRE+V D+ V D Q+ Sbjct: 704 GYDENSRLVVGNFSDQFGVDSETGDVFVRTELDRETVQRFDVTVVVDDMKAEENNDTQTD 763 Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG-EIRAHDPDEGPNAVVHYSIKG 728 + + I + D+ND+ P F F E +G I I A D D N +V Y + Sbjct: 764 SAELVITVLDVNDNAPEFIDLPDNFTTPETDQVGMVISVNILADDEDAEDNGIVIYELL- 822 Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVN 788 DD+ + + + + +D + PPL V +I +TDVN Sbjct: 823 -DDAGGL-VAISETTGILTVKQPIDKELNDSLTITFCAKDGGDPPLNTTVTRQIFITDVN 880 Query: 789 DNAPVMKDFQIIFNNYKDCFPVGPFG----RVPAYDADVT-DKLQYRILSGNNANLILLN 843 DN PV F + N G V A DAD L Y I +G ++N Sbjct: 881 DNTPV---FNVSLPNEASILEDTTNGTLVLTVYATDADPDFGDLTYTISAGVGLEDFVIN 937 Query: 844 ETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE 875 G +T+ +L+ L T+ V +DG+ + Sbjct: 938 PENGDITVQNELDREEQALYTLTVVASDGIRQ 969 Score = 146 bits (354), Expect = 8e-33 Identities = 165/640 (25%), Positives = 267/640 (41%), Gaps = 72/640 (11%) Query: 7 IHQQINVLDCNDHSPVFEMQ-QYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELV 65 + +QI + D ND++PVF + EAS+ E ++GT VLT+ ATD D ++ YTI Sbjct: 870 VTRQIFITDVNDNTPVFNVSLPNEASILEDTTNGTLVLTVYATDAD-PDFGDLTYTISA- 927 Query: 66 TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125 + ED F I+ +G + + LDRE+ A YT+ V A+D Sbjct: 928 ---GVGLED---------------FVINPENGDITVQNELDREEQALYTLTVVASDGIR- 968 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN- 184 D L T TI +D NDN+P+F+E + + + + V A + D + G N Sbjct: 969 -QDNLEVTITI----LDVNDNHPEFTESFPESTTISETAEPGSSVAAIVAVDDDEPGTNN 1023 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQD-GGSPSRSNTTQ 242 SA+RY + N F +D ++G V L T + Y LV+ A D G P ++ Sbjct: 1024 SAVRYIMTDENQSGFFKMDYVTGVVILNTTSTDALIPGVYVLVVVASDLGDPPLMTDPRN 1083 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 + + D ND AP F +V + I +A D D G N +T+ D Sbjct: 1084 FSVIVTDYNDEAPVFVQPKQGATVYVDENYSGHITTAEATDGDLGDNGVVTFAF-DTGLG 1142 Query: 303 GNVDLP-ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG----GDPPRSATATXXXXXX 357 D TID +G + + + DRET+ Y L+ G DP RS+ T Sbjct: 1143 ATDDYKYFTIDETTGAIEITSETDRETKEIYIRLLLGIIGMNAKSDPIRSSQVTFYVQVN 1202 Query: 358 XXXXXXXXFMPGQYEVELAEDEPP------------GTPVVTLT-ATDADED--NRLHYE 402 + + E +D P GT V T+ A D D D N+++Y Sbjct: 1203 DTDDNEPAYWGERTGPEGPQDPPEAALLYVQENLGEGTFVGTVPEAVDLDSDLYNQIYYF 1262 Query: 403 ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT-------------DSGGR 449 I + F + +G +T+ P+D ++ + L + A D Sbjct: 1263 IVSATSEDYFILDKYSGN--LTLVNPIDREKRPEFSLVIWADSNPDYEPDMNVIYDPLKE 1320 Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509 + A V + ++D N+ P FE YTA V G V+ V+A D D+G NA Y++ Sbjct: 1321 DNLARVTVTVSDVNDSPPRFEEDRYTAGVLYSTSFGVEVITVNAVDPDLGENAVTVYTIL 1380 Query: 510 SEISNEAVAHHDQQ---FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566 S+ S +A + + F IN G + + S Y++ + A D P+ +D Sbjct: 1381 SQKSYDADGNGGVEVDVFAIN--DGKVINSVTFQASDDSYYIVELQATDSLNPNFTDNAT 1438 Query: 567 VEISVV-DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 + + ++ ++ +F + +D + + A Sbjct: 1439 LSVYLMTEIEQVSALFADEPVNVRETQDDFIRLPTQAIAA 1478 Score = 41.1 bits (92), Expect = 0.43 Identities = 20/44 (45%), Positives = 25/44 (56%) Query: 445 DSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 D GR+DT V I+I DA N PVF PY S+ ED + T+ Sbjct: 7 DDEGRNDTTKVVISIRDAQNQPPVFIGQPYDKSIPEDTAVVHTM 50 >UniRef50_A7SN98 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 471 Score = 272 bits (668), Expect = 7e-71 Identities = 173/466 (37%), Positives = 252/466 (54%), Gaps = 27/466 (5%) Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS 164 LDRE YT+ VKATD PV R S+ A ++V ++D NDN P F +++Y V + E Sbjct: 11 LDRETKLNYTLDVKATD-VDPVDPRWSA-AVVYVEVLDSNDNAPVFKKQSYVVEMVEHSP 68 Query: 165 VT------DNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYE 218 T V+ IK TD DVG+N I Y+I+ GN F IDS S + +V +D E Sbjct: 69 TTFTVVKVGEKVVFLIKTTDRDVGSNGRISYSIVSGNVDGAFVIDS-SSVIRVVALVDRE 127 Query: 219 -QVRSYRLVIRAQDGGSPS-RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSI 276 Y L++ A+D G P+ + T ++ I I D+NDNAPRF + SV E+ +G + Sbjct: 128 AHPAGYSLLVVARDHGYPTPNAATARVNITISDINDNAPRFLKFTYSGSVREDRTVGTEV 187 Query: 277 VRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLV 336 V+VQA D D+G+ E+ + +T D G + T SG + + LDRE +A Y+L V Sbjct: 188 VQVQATDDDDGLAGEIVFAITGGDPEGLFSILNT----SGKITVARSLDREMKATYELTV 243 Query: 337 TATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED 396 TATD P+S + F + L+E PGTPV+T+ ATD D Sbjct: 244 TATDRAGDPKSTSVEVDITITDANDNKPVFTNIPATILLSESTIPGTPVITVVATDQDIG 303 Query: 397 NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTA 453 G + +G+F++ + G +++ LD++ +RY + + ATD G S T Sbjct: 304 VNGQVRYVGDSPKGKFAVNAITG--VVSTVGELDYEDVQRYTVYIVATDQGEPQLNSTTL 361 Query: 454 MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513 + I++ DAN+ P F A YTA V E+A GT V++V+AT+ D G +++ITY++S+ Sbjct: 362 HLNISLVDANDNNPTFTKAAYTAHVSEEATAGTNVIMVNATERDSGKDSKITYNISA--- 418 Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 + + H F IN TG I+ K LDRET S Y L V+ARDGG P Sbjct: 419 GDPLDH----FAINHLTGQISVRKALDRETTSLYTLLVSARDGGTP 460 Score = 257 bits (630), Expect = 3e-66 Identities = 175/488 (35%), Positives = 252/488 (51%), Gaps = 35/488 (7%) Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLINIRDVNDNAPRFYTSLFQ 263 ++GD+ V LD E +Y L ++A D R + + + + D NDNAP F + Sbjct: 1 MTGDIRAVGLLDRETKLNYTLDVKATDVDPVDPRWSAAVVYVEVLDSNDNAPVFKKQSYV 60 Query: 264 ESVSENVPIGYSIVRV--------QAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315 + E+ P +++V+V + D D G N ++Y++ +GNVD ID S Sbjct: 61 VEMVEHSPTTFTVVKVGEKVVFLIKTTDRDVGSNGRISYSIV----SGNVDGAFVIDS-S 115 Query: 316 GWVYTSGQLDRETQ-AKYQLLVTATDGGDP-PRSATATXXXXXXXXXXXXXXFMPGQYEV 373 + +DRE A Y LLV A D G P P +ATA F+ Y Sbjct: 116 SVIRVVALVDREAHPAGYSLLVVARDHGYPTPNAATARVNITISDINDNAPRFLKFTYSG 175 Query: 374 ELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431 + ED GT VV + ATD D+ + + ITGG+ G FSI + +G+ ITVA+ LD Sbjct: 176 SVREDRTVGTEVVQVQATDDDDGLAGEIVFAITGGDPEGLFSILNTSGK--ITVARSLDR 233 Query: 432 KQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 + + Y LTV+ATD G +S + V I ITDAN+ PVF N P T + E GT V+ Sbjct: 234 EMKATYELTVTATDRAGDPKSTSVEVDITITDANDNKPVFTNIPATILLSESTIPGTPVI 293 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 V ATD D+G+N Q+ Y S +F +N TG ++T LD E + Y + Sbjct: 294 TVVATDQDIGVNGQVRYVGDSPKG---------KFAVNAITGVVSTVGELDYEDVQRYTV 344 Query: 550 TVTARDGGVPSLSDTT-DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 + A D G P L+ TT + IS+VD NDN P F + YTA++ E+A GT+V V AT+ Sbjct: 345 YIVATDQGEPQLNSTTLHLNISLVDANDNNPTFTKAAYTAHVSEEATAGTNVIMVNATER 404 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ- 667 D G + +I Y + D + F I+ +G I KALDRE+ + + L A DGGTPP+ Sbjct: 405 DSGKDSKITYNISAGDPLD-HFAINHLTGQISVRKALDRETTSLYTLLVSARDGGTPPRF 463 Query: 668 -SSTVIVH 674 +TV++H Sbjct: 464 GQATVLIH 471 Score = 206 bits (503), Expect = 7e-51 Identities = 150/445 (33%), Positives = 215/445 (48%), Gaps = 31/445 (6%) Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGGDP--PRSATATXXXXXXXXXXXXXXFMPGQYE 372 +G + G LDRET+ Y L V ATD DP PR + A F Y Sbjct: 2 TGDIRAVGLLDRETKLNYTLDVKATDV-DPVDPRWSAAVVYVEVLDSNDNAPVFKKQSYV 60 Query: 373 VELAEDEPP-------GTPVVTLTAT---DADEDNRLHYEITGGNTRGRFSITSQNGRGL 422 VE+ E P G VV L T D + R+ Y I GN G F I S + + Sbjct: 61 VEMVEHSPTTFTVVKVGEKVVFLIKTTDRDVGSNGRISYSIVSGNVDGAFVIDSSS---V 117 Query: 423 ITVAQPLDFKQERR-YVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASV 478 I V +D + Y L V A D G + TA V I I+D N+ AP F Y+ SV Sbjct: 118 IRVVALVDREAHPAGYSLLVVARDHGYPTPNAATARVNITISDINDNAPRFLKFTYSGSV 177 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 ED +GT V+ V ATD D G+ +I ++++ + F I +G IT + Sbjct: 178 REDRTVGTEVVQVQATDDDDGLAGEIVFAITG-------GDPEGLFSILNTSGKITVARS 230 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 LDRE + Y LTVTA D S + +V+I++ D NDN+PVF T + E + GT Sbjct: 231 LDREMKATYELTVTATDRAGDPKSTSVEVDITITDANDNKPVFTNIPATILLSESTIPGT 290 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 V V ATD D+G+NG++ Y D +G F ++ +GV+ T LD E V + + V Sbjct: 291 PVITVVATDQDIGVNGQVRY---VGDSPKGKFAVNAITGVVSTVGELDYEDVQRYTVYIV 347 Query: 659 AIDGGTPPQSSTVI-VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A D G P +ST + ++I + D ND+ P F T ++SE + GT + + A + D G Sbjct: 348 ATDQGEPQLNSTTLHLNISLVDANDNNPTFTKAAYTAHVSEEATAGTNVIMVNATERDSG 407 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQG 742 ++ + Y+I GD + F++ G Sbjct: 408 KDSKITYNISAGDPLDHFAINHLTG 432 Score = 190 bits (462), Expect = 6e-46 Identities = 153/463 (33%), Positives = 224/463 (48%), Gaps = 35/463 (7%) Query: 429 LDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 LD + + Y L V ATD R A+V + + D+N+ APVF+ Y + E +P Sbjct: 11 LDRETKLNYTLDVKATDVDPVDPRWSAAVVYVEVLDSNDNAPVFKKQSYVVEMVEHSPTT 70 Query: 486 TTVL--------VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 TV+ ++ TD DVG N +I+YS+ S + D FVI+ + I Sbjct: 71 FTVVKVGEKVVFLIKTTDRDVGSNGRISYSIVS-------GNVDGAFVID-SSSVIRVVA 122 Query: 538 LLDRETM-SGYLLTVTARDGGVPSLSDTTD-VEISVVDVNDNEPVFKQQLYTANIMEDAL 595 L+DRE +GY L V ARD G P+ + T V I++ D+NDN P F + Y+ ++ ED Sbjct: 123 LVDREAHPAGYSLLVVARDHGYPTPNAATARVNITISDINDNAPRFLKFTYSGSVREDRT 182 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655 VGT V QV ATD D GL G I + + D EG F I SG I ++LDRE AT++L Sbjct: 183 VGTEVVQVQATDDDDGLAGEIVFAITGGD-PEGLFSILNTSGKITVARSLDREMKATYEL 241 Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 A D P+S++V V I I D ND+ PVF + T +SE++ GT + + A D D Sbjct: 242 TVTATDRAGDPKSTSVEVDITITDANDNKPVFTNIPATILLSESTIPGTPVITVVATDQD 301 Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP--P 773 G N V Y G F++ G + T+ +LDYE ++ Y + I A P Sbjct: 302 IGVNGQVRYV--GDSPKGKFAVNAITGV----VSTVGELDYEDVQR-YTVYIVATDQGEP 354 Query: 774 LWND--VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQY 829 N + + I + D NDN P + ++ V A + D K+ Y Sbjct: 355 QLNSTTLHLNISLVDANDNNPTFTKAAYTAHVSEEATAGTNVIMVNATERDSGKDSKITY 414 Query: 830 RILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 I +G+ + +N TG +++ L+ L T+ VS DG Sbjct: 415 NISAGDPLDHFAINHLTGQISVRKALDRETTSLYTLLVSARDG 457 Score = 180 bits (439), Expect = 4e-43 Identities = 138/449 (30%), Positives = 215/449 (47%), Gaps = 44/449 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT--------LKATDQDIGKNAEVEYTI 62 + VLD ND++PVF+ Q Y + E + + TV+ +K TD+D+G N + Y+I Sbjct: 42 VEVLDSNDNAPVFKKQSYVVEMVEHSPTTFTVVKVGEKVVFLIKTTDRDVGSNGRISYSI 101 Query: 63 ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREK-VARYTVLVKATD 121 V F ID S + A +DRE A Y++LV A D Sbjct: 102 -------------------VSGNVDGAFVIDS-SSVIRVVALVDREAHPAGYSLLVVARD 141 Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181 P + ++TA +++ I D NDN P+F + TY+ SV ED +V + +++ATD D Sbjct: 142 HGYPTPN--AATARVNITISDINDNAPRFLKFTYSGSVREDRTVGTE--VVQVQATDDDD 197 Query: 182 GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 G I +AI GG+ + FSI + SG +++ ++LD E +Y L + A D +S + Sbjct: 198 GLAGEIVFAITGGDPEGLFSILNTSGKITVARSLDREMKATYELTVTATDRAGDPKSTSV 257 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 ++ I I D NDN P F +SE+ G ++ V A D D GVN ++ Y Sbjct: 258 EVDITITDANDNKPVFTNIPATILLSESTIPGTPVITVVATDQDIGVNGQVRY--VGDSP 315 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP-RSATATXXXXXXXXX 360 G ++ +G V T G+LD E +Y + + ATD G+P S T Sbjct: 316 KGK----FAVNAITGVVSTVGELDYEDVQRYTVYIVATDQGEPQLNSTTLHLNISLVDAN 371 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQN 418 F Y ++E+ GT V+ + AT+ D +D+++ Y I+ G+ F+I Sbjct: 372 DNNPTFTKAAYTAHVSEEATAGTNVIMVNATERDSGKDSKITYNISAGDPLDHFAINHLT 431 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSG 447 G+ I+V + LD + Y L VSA D G Sbjct: 432 GQ--ISVRKALDRETTSLYTLLVSARDGG 458 Score = 178 bits (433), Expect = 2e-42 Identities = 120/342 (35%), Positives = 180/342 (52%), Gaps = 31/342 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D ND++P F Y SVRE + GT V+ ++ATD D G E+ + I T Sbjct: 156 ITISDINDNAPRFLKFTYSGSVREDRTVGTEVVQVQATDDDDGLAGEIVFAI---TGG-- 210 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +PE +F I SG + SLDRE A Y + V ATD+A D Sbjct: 211 DPEG--------------LFSILNTSGKITVARSLDREMKATYELTVTATDRAG---DPK 253 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S++ + + I D NDN P F+ T+ + E ++ PVI + ATD D+G N +RY Sbjct: 254 STSVEVDITITDANDNKPVFTNIPATILLSES-TIPGTPVITVV-ATDQDIGVNGQVRY- 310 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT-QLLINIRD 249 +G + + +F++++++G VS V LDYE V+ Y + I A D G P ++TT L I++ D Sbjct: 311 -VGDSPKGKFAVNAITGVVSTVGELDYEDVQRYTVYIVATDQGEPQLNSTTLHLNISLVD 369 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 NDN P F + + VSE G +++ V A + D G ++++TY ++ D + Sbjct: 370 ANDNNPTFTKAAYTAHVSEEATAGTNVIMVNATERDSGKDSKITYNISAGDPLDH----F 425 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 I+ +G + LDRET + Y LLV+A DGG PPR AT Sbjct: 426 AINHLTGQISVRKALDRETTSLYTLLVSARDGGTPPRFGQAT 467 Score = 153 bits (371), Expect = 7e-35 Identities = 119/356 (33%), Positives = 170/356 (47%), Gaps = 21/356 (5%) Query: 530 TGAITTNKLLDRETMSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588 TG I LLDRET Y L V A D V V + V+D NDN PVFK+Q Y Sbjct: 2 TGDIRAVGLLDRETKLNYTLDVKATDVDPVDPRWSAAVVYVEVLDSNDNAPVFKKQSYVV 61 Query: 589 NIMEDALVGTSVSQVG--------ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640 ++E + +V +VG TD DVG NGRI Y + +G+FVID +S VIR Sbjct: 62 EMVEHSPTTFTVVKVGEKVVFLIKTTDRDVGSNGRISYSI-VSGNVDGAFVID-SSSVIR 119 Query: 641 TNKALDRES-VATHDLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698 +DRE+ A + L VA D G P P ++T V+I I DIND+ P F + + E Sbjct: 120 VVALVDREAHPAGYSLLVVARDHGYPTPNAATARVNITISDINDNAPRFLKFTYSGSVRE 179 Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758 + +GT + +++A D D+G + ++I GGD FS+ G ++ LD E Sbjct: 180 DRTVGTEVVQVQATDDDDGLAGEIVFAITGGDPEGLFSILNTSG----KITVARSLDREM 235 Query: 759 PRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR 815 + YEL + A A P V V+I +TD NDN PV + + P P Sbjct: 236 -KATYELTVTATDRAGDPKSTSVEVDITITDANDNKPVFTNIPATILLSESTIPGTPVIT 294 Query: 816 VPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 V A D D+ Q R + + +N TG ++ +L+ + T+ + TD Sbjct: 295 VVATDQDIGVNGQVRYVGDSPKGKFAVNAITGVVSTVGELDYEDVQRYTVYIVATD 350 Score = 129 bits (311), Expect = 1e-27 Identities = 85/242 (35%), Positives = 126/242 (52%), Gaps = 29/242 (11%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 + I + D ND+ PVF + E GT V+T+ ATDQDIG N +V Y + Sbjct: 257 VEVDITITDANDNKPVFTNIPATILLSESTIPGTPVITVVATDQDIGVNGQVRYVGD--- 313 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 +P+ F ++ +G + T LD E V RYTV + ATDQ P Sbjct: 314 ----SPKGK--------------FAVNAITGVVSTVGELDYEDVQRYTVYIVATDQGEP- 354 Query: 127 SDRLSSTATIHVNI--IDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184 +L+ST T+H+NI +D NDN P F++ YT V E+ + N ++ + AT+ D G + Sbjct: 355 --QLNST-TLHLNISLVDANDNNPTFTKAAYTAHVSEEATAGTNVIM--VNATERDSGKD 409 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 S I Y I G+ F+I+ L+G +S+ K LD E Y L++ A+DGG+P R +L Sbjct: 410 SKITYNISAGDPLDHFAINHLTGQISVRKALDRETTSLYTLLVSARDGGTPPRFGQATVL 469 Query: 245 IN 246 I+ Sbjct: 470 IH 471 Score = 80.6 bits (190), Expect = 6e-13 Identities = 70/257 (27%), Positives = 119/257 (46%), Gaps = 18/257 (7%) Query: 636 SGVIRTNKALDRESVATH--DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693 +G IR LDRE+ + D+KA +D P+ S +V++++ D ND+ PVF+ Sbjct: 2 TGDIRAVGLLDRETKLNYTLDVKATDVDP-VDPRWSAAVVYVEVLDSNDNAPVFKKQSYV 60 Query: 694 FYISENSPIGTTI---GE-----IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745 + E+SP T+ GE I+ D D G N + YSI G+ +F +++ S Sbjct: 61 VEMVEHSPTTFTVVKVGEKVVFLIKTTDRDVGSNGRISYSIVSGNVDGAFVIDS---SSV 117 Query: 746 AELVTMVDLDYESPRKKYELVIRAASPPLWN--DVRVEILVTDVNDNAPVMKDFQIIFNN 803 +V +VD + +V R P N RV I ++D+NDNAP F + Sbjct: 118 IRVVALVDREAHPAGYSLLVVARDHGYPTPNAATARVNITISDINDNAPRFLKFTYSGSV 177 Query: 804 YKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPK 861 +D +V A D D + ++ + I G+ L + T+G +T++ L+ + Sbjct: 178 REDRTVGTEVVQVQATDDDDGLAGEIVFAITGGDPEGLFSILNTSGKITVARSLDREMKA 237 Query: 862 LATMEVSVTDGVNEIKA 878 + V+ TD + K+ Sbjct: 238 TYELTVTATDRAGDPKS 254 >UniRef50_UPI0000DB71FC Cluster: PREDICTED: similar to Cad87A CG6977-PA; n=2; Endopterygota|Rep: PREDICTED: similar to Cad87A CG6977-PA - Apis mellifera Length = 1907 Score = 272 bits (667), Expect = 9e-71 Identities = 274/915 (29%), Positives = 410/915 (44%), Gaps = 114/915 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D N+++PVF + Y AS+ E + GT V + ATD D G NAE+ Y I+ D Sbjct: 677 ITIRDVNNNAPVFPHELYTASLPEISPIGTVVEEVTATDADTGINAELVYRIQKGAFDD- 735 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F I+ +G + LD + Y V V A D+ +P L Sbjct: 736 -------------------FTINETTGIVTVFRKLDYDNKNTYHVEVIAFDKGTP---SL 773 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + T T+ +N+ + ND P F+ +T V ED + V +KATD D A+ +A Sbjct: 774 TGTTTLMINVENSNDKAPYFTPETQRAEVTEDTPI--GTVFTTLKATDPDSTNVEALNFA 831 Query: 191 I------IGGNTQMQ---------FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP 235 I I N Q F++D +G VS+V++LD + + + + D +P Sbjct: 832 ISEPITAIDRNGQQVNDSKSFKDFFAVDRATGQVSVVRSLDRDIAATVSITVVVSDTTAP 891 Query: 236 S-RSNTTQLLINIRDVNDNAPRFYTSLFQES------VSENVPIGYSIVRVQAYDADEGV 288 + + L++ I DVN AP F +E+ + E P G + A DAD + Sbjct: 892 TLQQGRGTLVVTIIDVNHMAPEFLKPWTRENPRYLIEMQEEQPTGAIVGAFTAVDADSNI 951 Query: 289 NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348 Y + N+D +T G V TS +D E + + V A D G P SA Sbjct: 952 AG---YAIIPPSPYFNID-NVT-----GIVRTSQVIDYEETKQLEFTVVAYDSGVPQLSA 1002 Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGG 406 T F Y + E+ PPGT V+ + ATD DE + Y + G Sbjct: 1003 TTKVIVTVININDQDPKFEKELYNASVKENSPPGTHVIVVKATDGDEGPFGEVSYSLIGD 1062 Query: 407 NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD----SGGRSDTAMVQINITDA 462 + F+I + G + A LD + +TV A+D + RS T V + + D Sbjct: 1063 HAAD-FNIGHETGEITVGSAAVLDREITPNITITVMASDGAHINSRRSTTVPVVVKLIDV 1121 Query: 463 NNYAPVFENAPYTASVFEDAPIG--TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520 N+ P+F Y ASV E+ P+ +L V A D D GIN ++ Y++ NE+ Sbjct: 1122 NDNRPIFTQHSYRASVAENLPVNPPAPILQVRAVDHDEGINGEVWYTIIHGNENES---- 1177 Query: 521 DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEP 579 F +N +TG + L S Y + V ARDG G SD V+I V VN ++P Sbjct: 1178 ---FSLNHETGILYPGAALLGRAGS-YRIEVEARDGAGNGPHSDKCYVDIRVTPVNQHKP 1233 Query: 580 VFKQQLYTANIME----DALVGTSVSQVGATDADVGLNGRIHYELDPKDR---EEGSFVI 632 F T +E ++ + V A D D G NGR+ Y L +R E F I Sbjct: 1234 QFVLPELTNATVEVPENTGVLNYLILTVKAIDRDPGENGRVSYHLKVGNRNIQETEEFSI 1293 Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV-IVHIKIEDINDSPPVFESDC 691 D +G +R+ LDRE + +L VA D GTP T+ ++ +++ D ND+ P F + Sbjct: 1294 DQETGELRSKIILDREVKSKFELVLVAADHGTPTAYETLRLLTVQLVDTNDNTPQFYDE- 1352 Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751 F ISEN P +G++ A D DEG +A V+Y I+ G+++ +F ++ GS + T Sbjct: 1353 YHFQISENRPKDYFVGKVIAEDKDEGRHAKVYYYIEAGNENYAFYIDKSDGS----IYTN 1408 Query: 752 VDLDYESPRKKYELVIRAA-------SP-----PLWND-----VRVEILVTDVNDNAPVM 794 D E+ R KY L I A+ SP PL ++ V V I++ D NDN+P+ Sbjct: 1409 KSFDRET-RDKYVLSILASNDPDIYISPADAGRPLMHNTDHGYVNVTIIILDENDNSPIF 1467 Query: 795 K--DFQIIFNNYKDCFPVGPF-GRVPAYDADVTDK--LQYRILSGNNANLILLNETTGSM 849 + D+ N+ + V F +V A D DV D L Y + S N + +GS+ Sbjct: 1468 ERNDYYAGVNSMAN---VNDFVTKVTASDLDVGDNGTLHYYVASA-NLYKYGSEKPSGSI 1523 Query: 850 TLSPQLNTNVPKLAT 864 SP + T KL T Sbjct: 1524 VPSPFIVTQDGKLVT 1538 Score = 252 bits (616), Expect = 1e-64 Identities = 239/834 (28%), Positives = 384/834 (46%), Gaps = 94/834 (11%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLT-LKATDQDIGKNAEVEYTIELVTADTLN 71 VLD ND+ P F YEA E G+T+L+ +K D D+ + TI+L T Sbjct: 119 VLDDNDNPPRFLNVPYEAVAEEDLPVGSTILSGIKVIDPDL-----LGDTIDL----TCV 169 Query: 72 PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131 P+ V R + +GAL+ R LD + Y +L++A+D + + Sbjct: 170 PQPQFLDACEKFGIVDVEKRQNSYTGALVLRQPLDYRERPFYQLLLRASDGLN------N 223 Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191 T + + + D ++ P+F + + T V ED + ++ +KA D D G + Y + Sbjct: 224 ETTGVEIKVADIQNSPPEFLD-SLTGVVREDDPI--GTLVMTVKARDGDRGMPRKMIYEL 280 Query: 192 IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS----YRLVIRAQD--GGSPSRSN----TT 241 + N F +D +G++ K L+ E ++ L +RA++ G P N T Sbjct: 281 V-TNPFDYFLLDDETGELRTAKPLNREALKDSTGVLTLKVRARELIDGMPGNDNLTVSTA 339 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 + + I+DVND P F + + ENVP G + + D V +++ +D Sbjct: 340 EATVTIKDVNDEPPTFNRREYNIEIPENVPNGTPLPHLDMTVKDPDVGLNSVFSLRLEDI 399 Query: 302 TGNVDLPITIDPRSGWVYTS-------GQLDRE--TQAKYQLLVTATD-GGDPPRSATAT 351 T D TI+P TS G LD E Q K+ +LV A + DP S+TAT Sbjct: 400 T---DGAFTIEPTMATGSTSVNIRVANGSLDYENPNQRKFIILVVAEEVHTDPKLSSTAT 456 Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN----RLHYEITGGN 407 F Y + E PPGTPV+T+TA D D + Y++ G Sbjct: 457 VTVSITDANDNSPTFSNPTYTAVVLETAPPGTPVITITAKDRDSGRFGTAGIAYQLLGQG 516 Query: 408 TRGRFSITSQNGRGLITV---AQP-----LDFKQERRYVLTVSATDSGGRSDTAMV--QI 457 + FS+ ++ G+ITV A P LD++++ Y LT ATD G+ T V +I Sbjct: 517 AQ-HFSVDRKS--GIITVAPCANPGTSPCLDYEEQTEYFLTYKATDDDGQGQTTSVSLRI 573 Query: 458 NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517 +++DAN+ P F Y A + E A L V A D D ++ITY++ + + + Sbjct: 574 SLSDANDSPPRFLQDKYRAVIDEGAEKFEPDLKVQARDKDK--TSKITYAI---VGGDEL 628 Query: 518 AHHDQQFVINPQTGAIT-TNK---LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 F I+ TG IT NK L T L + A DG D+ V I++ D Sbjct: 629 ----DLFAIDQDTGEITIKNKGPVDLTNSTHDWIALVIQASDG---IFVDSAIVNITIRD 681 Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633 VN+N PVF +LYTA++ E + +GT V +V ATDAD G+N + Y + ++ F I+ Sbjct: 682 VNNNAPVFPHELYTASLPEISPIGTVVEEVTATDADTGINAELVYRIQKGAFDD--FTIN 739 Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693 +G++ + LD ++ T+ ++ +A D GTP + T + I +E+ ND P F + Sbjct: 740 ETTGIVTVFRKLDYDNKNTYHVEVIAFDKGTPSLTGTTTLMINVENSNDKAPYFTPETQR 799 Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI--------KGG---DDSNSFS--LETR 740 ++E++PIGT ++A DPD ++++I + G +DS SF Sbjct: 800 AEVTEDTPIGTVFTTLKATDPDSTNVEALNFAISEPITAIDRNGQQVNDSKSFKDFFAVD 859 Query: 741 QGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVT--DVNDNAP 792 + + + +V +D D + +V+ + P R ++VT DVN AP Sbjct: 860 RATGQVSVVRSLDRDI-AATVSITVVVSDTTAPTLQQGRGTLVVTIIDVNHMAP 912 Score = 246 bits (601), Expect = 9e-63 Identities = 260/918 (28%), Positives = 405/918 (44%), Gaps = 96/918 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I V D + P F + VRE GT V+T+KA D D G ++ Y ELVT Sbjct: 229 EIKVADIQNSPPEF-LDSLTGVVREDDPIGTLVMTVKARDGDRGMPRKMIY--ELVT--- 282 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR----YTVLVKATD--QA 123 NP D F +D +G L T L+RE + T+ V+A + Sbjct: 283 -NPFD--------------YFLLDDETGELRTAKPLNREALKDSTGVLTLKVRARELIDG 327 Query: 124 SPVSDRLS-STATIHVNIIDDNDNYPQFSEKTYTVSVDEDI-SVTDNPVIAKIKATDADV 181 P +D L+ STA V I D ND P F+ + Y + + E++ + T P + + D DV Sbjct: 328 MPGNDNLTVSTAEATVTIKDVNDEPPTFNRREYNIEIPENVPNGTPLPHL-DMTVKDPDV 386 Query: 182 GANS--AIRYAII--GGNT-QMQFSIDSLSGDVSLVK-TLDYEQVRSYR---LVIRAQDG 232 G NS ++R I G T + + S S ++ + +LDYE + LV+ + Sbjct: 387 GLNSVFSLRLEDITDGAFTIEPTMATGSTSVNIRVANGSLDYENPNQRKFIILVVAEEVH 446 Query: 233 GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV--NA 290 P S+T + ++I D NDN+P F + V E P G ++ + A D D G A Sbjct: 447 TDPKLSSTATVTVSITDANDNSPTFSNPTYTAVVLETAPPGTPVITITAKDRDSGRFGTA 506 Query: 291 ELTYTMTDKDYTG-NVDLP---ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR 346 + Y + + +VD IT+ P + TS LD E Q +Y L ATD + Sbjct: 507 GIAYQLLGQGAQHFSVDRKSGIITVAPCAN-PGTSPCLDYEEQTEYFLTYKATDDDGQGQ 565 Query: 347 SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG 406 + + + F+ +Y + E P + + A D D+ +++ Y I GG Sbjct: 566 TTSVSLRISLSDANDSPPRFLQDKYRAVIDEGAEKFEPDLKVQARDKDKTSKITYAIVGG 625 Query: 407 NTRGRFSITSQNGRGLITVAQPLDFKQERR--YVLTVSATDSGGRSDTAMVQINITDANN 464 + F+I G I P+D L + A+D G D+A+V I I D NN Sbjct: 626 DELDLFAIDQDTGEITIKNKGPVDLTNSTHDWIALVIQASD-GIFVDSAIVNITIRDVNN 684 Query: 465 YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524 APVF + YTAS+ E +PIGT V V+ATD+D GINA++ Y + ++ F Sbjct: 685 NAPVFPHELYTASLPEISPIGTVVEEVTATDADTGINAELVYRIQKGAFDD--------F 736 Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584 IN TG +T + LD + + Y + V A D G PSL+ TT + I+V + ND P F + Sbjct: 737 TINETTGIVTVFRKLDYDNKNTYHVEVIAFDKGTPSLTGTTTLMINVENSNDKAPYFTPE 796 Query: 585 LYTANIMEDALVGTSVSQVGATDAD----VGLNGRIHYELDPKDRE----------EGSF 630 A + ED +GT + + ATD D LN I + DR + F Sbjct: 797 TQRAEVTEDTPIGTVFTTLKATDPDSTNVEALNFAISEPITAIDRNGQQVNDSKSFKDFF 856 Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP-QSSTVIVHIKIEDINDSPPVF-- 687 +D A+G + ++LDR+ AT + V D P Q + + I D+N P F Sbjct: 857 AVDRATGQVSVVRSLDRDIAATVSITVVVSDTTAPTLQQGRGTLVVTIIDVNHMAPEFLK 916 Query: 688 ----ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 E+ + E P G +G A D D + Y+I S F+++ G Sbjct: 917 PWTRENPRYLIEMQEEQPTGAIVGAFTAVDADSN---IAGYAII--PPSPYFNIDNVTGI 971 Query: 744 DKAELVTMVDLDYESPRKKYELVIRAAS--PPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801 + V +DYE ++ V+ S P L +V + V ++ND P + ++ Sbjct: 972 VRTSQV----IDYEETKQLEFTVVAYDSGVPQLSATTKVIVTVININDQDPKFEK-ELYN 1026 Query: 802 NNYKDCFPVGPFG-RVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTL--SPQLN 856 + K+ P G V A D D ++ Y ++ G++A + TG +T+ + L+ Sbjct: 1027 ASVKENSPPGTHVIVVKATDGDEGPFGEVSYSLI-GDHAADFNIGHETGEITVGSAAVLD 1085 Query: 857 TNVPKLATMEVSVTDGVN 874 + T+ V +DG + Sbjct: 1086 REITPNITITVMASDGAH 1103 Score = 216 bits (528), Expect = 6e-54 Identities = 212/744 (28%), Positives = 328/744 (44%), Gaps = 58/744 (7%) Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 D F ++ R+G + LDRE+ V D+ +V ++DDNDN Sbjct: 67 DHFVVNPRTGVITLAKPLDREENGTIRFRVTLEDEVPAGQQPNIVGVDAYVIVLDDNDNP 126 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG----------GNTQ 197 P+F Y +ED+ V + +++ IK D D+ ++ + G Sbjct: 127 PRFLNVPYEAVAEEDLPV-GSTILSGIKVIDPDLLGDTIDLTCVPQPQFLDACEKFGIVD 185 Query: 198 MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF 257 ++ +S +G + L + LDY + Y+L++RA DG + TT + I + D+ ++ P F Sbjct: 186 VEKRQNSYTGALVLRQPLDYRERPFYQLLLRASDG---LNNETTGVEIKVADIQNSPPEF 242 Query: 258 YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317 SL V E+ PIG ++ V+A D D G+ ++ Y + T D +D +G Sbjct: 243 LDSL-TGVVREDDPIGTLVMTVKARDGDRGMPRKMIYELV----TNPFDY-FLLDDETGE 296 Query: 318 VYTSGQLDRET----------QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 + T+ L+RE + + + L+ G D +TA F Sbjct: 297 LRTAKPLNREALKDSTGVLTLKVRARELIDGMPGNDNLTVSTAEATVTIKDVNDEPPTFN 356 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT---GGNTRGRFSITSQNGRGL-- 422 +Y +E+ E+ P GTP+ L T D D L+ + T G F+I G Sbjct: 357 RREYNIEIPENVPNGTPLPHLDMTVKDPDVGLNSVFSLRLEDITDGAFTIEPTMATGSTS 416 Query: 423 --ITVAQ-PLDFK--QERRYVLTVSATD---SGGRSDTAMVQINITDANNYAPVFENAPY 474 I VA LD++ +R++++ V A + S TA V ++ITDAN+ +P F N Y Sbjct: 417 VNIRVANGSLDYENPNQRKFIILVVAEEVHTDPKLSSTATVTVSITDANDNSPTFSNPTY 476 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGI--NAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 TA V E AP GT V+ ++A D D G A I Y L + + + Sbjct: 477 TAVVLETAPPGTPVITITAKDRDSGRFGTAGIAYQLLGQGAQHFSVDRKSGIITVAPCAN 536 Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592 T+ LD E + Y LT A D + + + IS+ D ND+ P F Q Y A I E Sbjct: 537 PGTSPCLDYEEQTEYFLTYKATDDDGQGQTTSVSLRISLSDANDSPPRFLQDKYRAVIDE 596 Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR-TNKALDRESVA 651 A +V A D D +I Y + D E F ID +G I NK + + Sbjct: 597 GAEKFEPDLKVQARDKD--KTSKITYAIVGGD-ELDLFAIDQDTGEITIKNKGPVDLTNS 653 Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711 THD A+ I + IV+I I D+N++ PVF + T + E SPIGT + E+ A Sbjct: 654 THDWIALVIQASDGIFVDSAIVNITIRDVNNNAPVFPHELYTASLPEISPIGTVVEEVTA 713 Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV-DLDYESPRKKYELVIR-- 768 D D G NA + Y I+ G + F++ G +VT+ LDY++ + VI Sbjct: 714 TDADTGINAELVYRIQKG-AFDDFTINETTG-----IVTVFRKLDYDNKNTYHVEVIAFD 767 Query: 769 AASPPLWNDVRVEILVTDVNDNAP 792 +P L + I V + ND AP Sbjct: 768 KGTPSLTGTTTLMINVENSNDKAP 791 Score = 187 bits (456), Expect = 3e-45 Identities = 163/595 (27%), Positives = 268/595 (45%), Gaps = 54/595 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V++ ND P FE + Y ASV+E + GT V+ +KATD D G EV Y++ + Sbjct: 1008 VTVININDQDPKFEKELYNASVKENSPPGTHVIVVKATDGDEGPFGEVSYSL-------I 1060 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALL--TRASLDREKVARYTVLVKATDQASPVSD 128 A F I +G + + A LDRE T+ V A+D A ++ Sbjct: 1061 GDHAAD-------------FNIGHETGEITVGSAAVLDREITPNITITVMASDGAH-INS 1106 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 R S+T + V +ID NDN P F++ +Y SV E++ V I +++A D D G N + Sbjct: 1107 RRSTTVPVVVKLIDVNDNRPIFTQHSYRASVAENLPVNPPAPILQVRAVDHDEGINGEVW 1166 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG-GSPSRSNTTQLLINI 247 Y II GN FS++ +G + L + SYR+ + A+DG G+ S+ + I + Sbjct: 1167 YTIIHGNENESFSLNHETGILYPGAAL-LGRAGSYRIEVEARDGAGNGPHSDKCYVDIRV 1225 Query: 248 RDVNDNAPRFYTSLFQES---VSENVPI-GYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 VN + P+F + V EN + Y I+ V+A D D G N ++Y + + Sbjct: 1226 TPVNQHKPQFVLPELTNATVEVPENTGVLNYLILTVKAIDRDPGENGRVSYHLKVGNRNI 1285 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 +ID +G + + LDRE ++K++L++ A D G P T Sbjct: 1286 QETEEFSIDQETGELRSKIILDREVKSKFELVLVAADHGTPTAYETLRLLTVQLVDTNDN 1345 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRG 421 +Y +++E+ P V + A D DE +++Y I GN F I +G Sbjct: 1346 TPQFYDEYHFQISENRPKDYFVGKVIAEDKDEGRHAKVYYYIEAGNENYAFYIDKSDGS- 1404 Query: 422 LITVAQPLDFKQERRYVLTVSATDS---------GGRS---DTAMVQINIT----DANNY 465 I + D + +YVL++ A++ GR +T +N+T D N+ Sbjct: 1405 -IYTNKSFDRETRDKYVLSILASNDPDIYISPADAGRPLMHNTDHGYVNVTIIILDENDN 1463 Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL-SSEISNEAVAHHDQQF 524 +P+FE Y A V A + V V+A+D DVG N + Y + S+ + Sbjct: 1464 SPIFERNDYYAGVNSMANVNDFVTKVTASDLDVGDNGTLHYYVASANLYKYGSEKPSGSI 1523 Query: 525 VINP----QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575 V +P Q G + T+ + +++ V A++ +P T V + V + + Sbjct: 1524 VPSPFIVTQDGKLVTSGYMAEYNQDRFIVEVIAKEAAIPERYAMTRVHVWVFEAS 1578 Score = 180 bits (437), Expect = 7e-43 Identities = 196/715 (27%), Positives = 315/715 (44%), Gaps = 59/715 (8%) Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD----GGSPSRSNTTQLLINIRDVNDNAP 255 F ++ +G ++L K LD E+ + R + +D G P+ +I + D NDN P Sbjct: 69 FVVNPRTGVITLAKPLDREENGTIRFRVTLEDEVPAGQQPNIVGVDAYVI-VLDDNDNPP 127 Query: 256 RFYTSLFQESVSENVPIGYSIVR-VQAYDAD-EGVNAELTYTMTDK-----DYTGNVDLP 308 RF ++ E++P+G +I+ ++ D D G +LT + + G VD+ Sbjct: 128 RFLNVPYEAVAEEDLPVGSTILSGIKVIDPDLLGDTIDLTCVPQPQFLDACEKFGIVDVE 187 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 + +G + LD + YQLL+ A+DG + T F+ Sbjct: 188 KRQNSYTGALVLRQPLDYRERPFYQLLLRASDG---LNNETTGVEIKVADIQNSPPEFLD 244 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 V + ED+P GT V+T+ A D D ++ YE+ N F + + G + A Sbjct: 245 SLTGV-VREDDPIGTLVMTVKARDGDRGMPRKMIYELV-TNPFDYFLLDDETGE--LRTA 300 Query: 427 QPLDFK--QERRYVLTVSA-----TDSGGRSD-----TAMVQINITDANNYAPVFENAPY 474 +PL+ + ++ VLT+ D +D TA + I D N+ P F Y Sbjct: 301 KPLNREALKDSTGVLTLKVRARELIDGMPGNDNLTVSTAEATVTIKDVNDEPPTFNRREY 360 Query: 475 TASVFEDAPIGTTV--LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 + E+ P GT + L ++ D DVG+N+ + L +I++ A + Sbjct: 361 NIEIPENVPNGTPLPHLDMTVKDPDVGLNSVFSLRL-EDITDGAFTIEPTMATGSTSVNI 419 Query: 533 ITTNKLLDRE--TMSGYLLTVTARDGGV-PSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589 N LD E +++ V A + P LS T V +S+ D NDN P F YTA Sbjct: 420 RVANGSLDYENPNQRKFIILVVAEEVHTDPKLSSTATVTVSITDANDNSPTFSNPTYTAV 479 Query: 590 IMEDALVGTSVSQVGATDADVGLNGR--IHYELDPKDREEGSFVIDPASGVIR------- 640 ++E A GT V + A D D G G I Y+L + + F +D SG+I Sbjct: 480 VLETAPPGTPVITITAKDRDSGRFGTAGIAYQLLGQGAQH--FSVDRKSGIITVAPCANP 537 Query: 641 -TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699 T+ LD E + L A D Q+++V + I + D NDSPP F D I E Sbjct: 538 GTSPCLDYEEQTEYFLTYKATDDDGQGQTTSVSLRISLSDANDSPPRFLQDKYRAVIDEG 597 Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759 + +++A D D+ + + Y+I GGD+ + F+++ G + VDL S Sbjct: 598 AEKFEPDLKVQARDKDK--TSKITYAIVGGDELDLFAIDQDTGEITIKNKGPVDLT-NST 654 Query: 760 RKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPA 818 LVI+A+ + V I + DVN+NAPV ++ + + P+G V A Sbjct: 655 HDWIALVIQASDGIFVDSAIVNITIRDVNNNAPVF-PHELYTASLPEISPIGTVVEEVTA 713 Query: 819 YDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 DAD + +L YRI G + +NETTG +T+ +L+ + +EV D Sbjct: 714 TDADTGINAELVYRIQKGAFDD-FTINETTGIVTVFRKLDYDNKNTYHVEVIAFD 767 Score = 144 bits (348), Expect = 4e-32 Identities = 149/517 (28%), Positives = 235/517 (45%), Gaps = 51/517 (9%) Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434 L+E GT V L D E + + Y I F + + G +IT+A+PLD ++ Sbjct: 36 LSESTKVGTEVFVLKGHDP-EGSPVKYGI---QLTDHFVVNPRTG--VITLAKPLDREEN 89 Query: 435 R--RYVLTVSATDSGGRSDTAM---VQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 R+ +T+ G+ + + + D N+ P F N PY A ED P+G+T+L Sbjct: 90 GTIRFRVTLEDEVPAGQQPNIVGVDAYVIVLDDNDNPPRFLNVPYEAVAEEDLPVGSTIL 149 Query: 490 V-VSATDSD-VGINAQITYSLSSEISN--EAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 + D D +G +T + + E D + N TGA+ + LD Sbjct: 150 SGIKVIDPDLLGDTIDLTCVPQPQFLDACEKFGIVDVEKRQNSYTGALVLRQPLDYRERP 209 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 Y L + A DG ++TT VEI V D+ ++ P F L T + ED +GT V V A Sbjct: 210 FYQLLLRASDG---LNNETTGVEIKVADIQNSPPEFLDSL-TGVVREDDPIGTLVMTVKA 265 Query: 606 TDADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRES------VATHDLKA 657 D D G+ ++ YEL +P D F++D +G +RT K L+RE+ V T ++A Sbjct: 266 RDGDRGMPRKMIYELVTNPFD----YFLLDDETGELRTAKPLNREALKDSTGVLTLKVRA 321 Query: 658 VAIDGGTPPQS----STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG--EIRA 711 + G P ST + I+D+ND PP F I EN P GT + ++ Sbjct: 322 RELIDGMPGNDNLTVSTAEATVTIKDVNDEPPTFNRREYNIEIPENVPNGTPLPHLDMTV 381 Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQ--GSDKAEL-VTMVDLDYESP-RKKYELVI 767 DPD G N+V ++ D +F++E GS + V LDYE+P ++K+ +++ Sbjct: 382 KDPDVGLNSVFSLRLEDITD-GAFTIEPTMATGSTSVNIRVANGSLDYENPNQRKFIILV 440 Query: 768 RA----ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV 823 A P L + V + +TD NDN+P + + P P + A D D Sbjct: 441 VAEEVHTDPKLSSTATVTVSITDANDNSPTFSNPTYTAVVLETAPPGTPVITITAKDRDS 500 Query: 824 ----TDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 T + Y++L G A ++ +G +T++P N Sbjct: 501 GRFGTAGIAYQLL-GQGAQHFSVDRKSGIITVAPCAN 536 Score = 43.2 bits (97), Expect = 0.11 Identities = 20/56 (35%), Positives = 31/56 (55%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 ++ I +LD ND+SP+FE Y A V A+ V + A+D D+G N + Y + Sbjct: 1451 VNVTIIILDENDNSPIFERNDYYAGVNSMANVNDFVTKVTASDLDVGDNGTLHYYV 1506 >UniRef50_Q96QU1 Cluster: Protocadherin-15 precursor; n=69; Euteleostomi|Rep: Protocadherin-15 precursor - Homo sapiens (Human) Length = 1955 Score = 272 bits (667), Expect = 9e-71 Identities = 254/836 (30%), Positives = 386/836 (46%), Gaps = 96/836 (11%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-----LKATDQDIGKNAEVEYTIEL 64 +I V D ND+SP F+ + Y A+V E GTT+ T ATD D G N ++EY I+ Sbjct: 134 RIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQY 193 Query: 65 VTADTLNPEDAXXXXXXXXXXVQDVFRIDGR-SGALLTRASLDREKVARYTVLVKATDQA 123 NP+D D F I +G ++ R L+ E RY V+++A D+A Sbjct: 194 ------NPDDPTS---------NDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRA 238 Query: 124 SPVSDRLSSTATIHVNIIDDNDNYPQF------------SEKTYTVSVDEDISVTD-NPV 170 +++R ++T T+ V+++D +D P F TY ++ E + + NP+ Sbjct: 239 QNLNERRTTTTTLTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPI 298 Query: 171 IA--KIKATDAD-----VGANSAIRYAIIGGNTQ---MQFSIDSLSGDVSLVKTLDYEQV 220 I I+A D D I Y+I+ G + F + + ++SL++ ++ + Sbjct: 299 IVTPPIQAIDQDRNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFH 358 Query: 221 RSYRLVIRA-QDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSI--- 276 + + LVI+A QD G P + L I I D N+ +P F +Q + E+ P+G +I Sbjct: 359 QKFDLVIKAEQDNGHPLPA-FAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDS 417 Query: 277 ------VRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA 330 +R+ A D D + + DYT +T + ++ +DRE Q Sbjct: 418 LNLTSPLRIVALDKDIEDTKDPELHLFLNDYTS--VFTVTQTGITRYLTLLQPVDREEQQ 475 Query: 331 KYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTA 390 Y +TA DG S F Y+V + D PG V+ LTA Sbjct: 476 TYTFSITAFDG--VQESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTA 533 Query: 391 TDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG- 447 DADE + + YEI G +G F I GLIT+A ++ R Y LTV A D+ Sbjct: 534 VDADEGSNGEITYEILVG-AQGDFIINKTT--GLITIAPGVEMIVGRTYALTVQAADNAP 590 Query: 448 ---GRSDTAMVQINITDANNYAPV-FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503 R+ V I + NN +P F Y+ + E +G +L + ATD + Sbjct: 591 PAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDS 647 Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD 563 ITY++ + + F ++ TG +T K LDRE+ Y+L +TA DG P + Sbjct: 648 ITYAIEN-------GDPQRVFNLSETTGILTLGKALDRESTDRYILIITASDGR-PDGTS 699 Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK 623 T V I V DVNDN PVF L + + V QV ATD D G+NG++HY L Sbjct: 700 TATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSL--- 756 Query: 624 DREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS 683 F I ++G I T L+RE ++L VA DG P+ ST+ + IK+ DI+D+ Sbjct: 757 GNFNNLFRI-TSNGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDN 815 Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 PVF + T + EN P GTTI +I A D D G N V Y I+ + + F+L G Sbjct: 816 SPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGAN--VSYRIRSPEVKHFFALHPFTG- 872 Query: 744 DKAELVTMVDLDYES-PRKKYELVIRAASPPLWNDV-----RVEILVTDVNDNAPV 793 EL + LDYE+ P ++ + + ++ + V ++V D+ND PV Sbjct: 873 ---ELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPV 925 Score = 244 bits (598), Expect = 2e-62 Identities = 212/733 (28%), Positives = 343/733 (46%), Gaps = 63/733 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V+D ND++P F Y+ V G +V+ L A D D G N E+ Y I LV A Sbjct: 497 IQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITYEI-LVGA--- 552 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 Q F I+ +G + ++ Y + V+A D A P ++R Sbjct: 553 ----------------QGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPP-AERR 595 Query: 131 SSTATIHVNIID-DNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 +S T+++ ++ +N + P+F + Y++ + E + V V+ ++ATD + +I Y Sbjct: 596 NSICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRV--GAVLLNLQATDRE---GDSITY 650 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 AI G+ Q F++ +G ++L K LD E Y L+I A DG P ++T + I + D Sbjct: 651 AIENGDPQRVFNLSETTGILTLGKALDRESTDRYILIITASDG-RPDGTSTATVNIVVTD 709 Query: 250 VNDNAPRFYTSLFQE-SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 VNDNAP F L + SV E + + +V+A D D G+N ++ Y++ GN + Sbjct: 710 VNDNAPVFDPYLPRNLSVVEEEANAF-VGQVKATDPDAGINGQVHYSL------GNFNNL 762 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 I +G +YT+ +L+RE + Y+L+V ATDG PR +T T F Sbjct: 763 FRITS-NGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTN 821 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 Y V + E+ P GT ++ + A D D + Y I + F++ G +++ + Sbjct: 822 STYTVLVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEVKHFFALHPFTGE--LSLLRS 879 Query: 429 LDFK----QERRYVLTVSATDSGGRSDT--AMVQINITDANNYAPVFENAPYTASVFEDA 482 LD++ QE V A D G A V + + D N+Y PVF Y V DA Sbjct: 880 LDYEAFPDQEASITFLVEAFDIYGTMPPGIATVTVIVKDMNDYPPVFSKRIYKGMVAPDA 939 Query: 483 PIGTTVLVVSATDSDV-GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 GT + V A D+D G+ A + + + + F + +G + T L+ Sbjct: 940 VKGTPITTVYAEDADPPGLPAS---RVRYRVDDVQFPYPASIFEVEEDSGRVITRVNLNE 996 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN-IMEDALVGTSV 600 E + + L V A D G P +S + V+I V+ + P F Q+ Y + E A GT V Sbjct: 997 EPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGEI-PRFTQEEYRPPPVSELATKGTMV 1055 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES-------VATH 653 + A +N I Y + EE +F I+ +GVI N LD E+ V Sbjct: 1056 GVISAA----AINQSIVYSI-VSGNEEDTFGINNITGVIYVNGPLDYETRTSYVLRVQAD 1110 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713 L+ V + P +S+T V+I+I+D N+ PPVF+ +SE++ + T++ ++A D Sbjct: 1111 SLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKFYIGGVSEDARMFTSVLRVKATD 1170 Query: 714 PDEGPNAVVHYSI 726 D G +V+ Y + Sbjct: 1171 KDTGNYSVMAYRL 1183 Score = 214 bits (523), Expect = 3e-53 Identities = 214/796 (26%), Positives = 362/796 (45%), Gaps = 66/796 (8%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKAT-DQASPVSDRLSSTATIHVNIIDDNDNYP 148 F + R+ L ++R+ ++ +++KA D P L + A +H+ I+D+N+ P Sbjct: 338 FHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQDNGHP----LPAFAGLHIEILDENNQSP 393 Query: 149 QFSEKTYTVSVDEDI----SVTDNPVIA---KIKATDADVGANSAIRYAIIGGNTQMQFS 201 F+ +Y + E +++D+ + +I A D D+ + + F+ Sbjct: 394 YFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALDKDIEDTKDPELHLFLNDYTSVFT 453 Query: 202 IDS--LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259 + ++ ++L++ +D E+ ++Y I A DG S + I + D NDN P F Sbjct: 454 VTQTGITRYLTLLQPVDREEQQTYTFSITAFDG--VQESEPVIVNIQVMDANDNTPTFPE 511 Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319 + V ++ G S++++ A DADEG N E+TY + I+ +G + Sbjct: 512 ISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITY-----EILVGAQGDFIINKTTGLIT 566 Query: 320 TSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXXXXFMPG-QYEVELA 376 + ++ Y L V A D P R++ T P Y +E++ Sbjct: 567 IAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIEVLPPNNQSPPRFPQLMYSLEIS 626 Query: 377 EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436 E G ++ L ATD + D+ + Y I G+ + F+++ G++T+ + LD + R Sbjct: 627 EAMRVGAVLLNLQATDREGDS-ITYAIENGDPQRVFNLSETT--GILTLGKALDRESTDR 683 Query: 437 YVLTVSATDSGGRSD---TAMVQINITDANNYAPVFE-NAPYTASVFEDAPIGTTVLVVS 492 Y+L ++A+D GR D TA V I +TD N+ APVF+ P SV E+ V V Sbjct: 684 YILIITASD--GRPDGTSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEE-EANAFVGQVK 740 Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552 ATD D GIN Q+ YSL + + F I G+I T L+RE Y L V Sbjct: 741 ATDPDAGINGQVHYSL---------GNFNNLFRIT-SNGSIYTAVKLNREVRDYYELVVV 790 Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612 A DG V T + I V+D++DN PVF YT + E+ GT++ Q+ A D D+G Sbjct: 791 ATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGA 850 Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKAL------DRESVATHDLKAVAIDGGTPP 666 N + Y + + + F + P +G + ++L D+E+ T ++A I G PP Sbjct: 851 N--VSYRIRSPEVKH-FFALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPP 907 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG--PNAVVHY 724 +TV V +K D+ND PPVF ++ ++ GT I + A D D P + V Y Sbjct: 908 GIATVTVIVK--DMNDYPPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRY 965 Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVE 781 + S+ + D ++T V+L+ E P ++LV+ A P + + V+ Sbjct: 966 RVDDVQFPYPASIFEVE-EDSGRVITRVNLN-EEPTTIFKLVVVAFDDGEPVMSSSATVK 1023 Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDKLQYRILSGNNANLI 840 ILV + P + + G G + A A + + Y I+SGN + Sbjct: 1024 ILVLHPGE-IPRFTQEEYRPPPVSELATKGTMVGVISA--AAINQSIVYSIVSGNEEDTF 1080 Query: 841 LLNETTGSMTLSPQLN 856 +N TG + ++ L+ Sbjct: 1081 GINNITGVIYVNGPLD 1096 Score = 206 bits (502), Expect = 9e-51 Identities = 210/779 (26%), Positives = 340/779 (43%), Gaps = 88/779 (11%) Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIK----ATDADVGANSAIRYAI 191 + + + D NDN P F ++Y +V+E ++ + ATD D G N I Y + Sbjct: 133 VRIVVRDRNDNSPTFKHESYYATVNE-LTPVGTTIFTGFSGDNGATDIDDGPNGQIEY-V 190 Query: 192 IGGNTQMQFSIDS------LSGDVSLVKTLDYEQVRSYRLVIRAQDGG---SPSRSNTTQ 242 I N S D+ L+G++ L K L+YE Y ++I+A D + R+ TT Sbjct: 191 IQYNPDDPTSNDTFEIPLMLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTT 250 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYS---------------IVR--VQAYDAD 285 L +++ D +D P F + + + P+ Y IV +QA D D Sbjct: 251 LTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQD 310 Query: 286 EGVNAE-----LTYTM---TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVT 337 + + Y++ T +DY + PR+ + ++R+ K+ L++ Sbjct: 311 RNIQPPSDRPGILYSILVGTPEDYPRFFHM----HPRTAELSLLEPVNRDFHQKFDLVIK 366 Query: 338 ATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG---------TPVVTL 388 A P A A F Y+ + E P G T + + Sbjct: 367 AEQDNGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRI 426 Query: 389 TATDAD----EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444 A D D +D LH + + F++T +T+ QP+D ++++ Y +++A Sbjct: 427 VALDKDIEDTKDPELHLFL--NDYTSVFTVTQTGITRYLTLLQPVDREEQQTYTFSITAF 484 Query: 445 DSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504 D S+ +V I + DAN+ P F Y V+ D G +V+ ++A D+D G N +I Sbjct: 485 DGVQESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEI 544 Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS--LS 562 TY E + F+IN TG IT ++ Y LTV A D P+ + Sbjct: 545 TY--------EILVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRN 596 Query: 563 DTTDVEISVVDVNDNEPV-FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621 V I V+ N+ P F Q +Y+ I E VG + + ATD + I Y ++ Sbjct: 597 SICTVYIEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIE 653 Query: 622 PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681 D + F + +G++ KALDRES + L A D G P +ST V+I + D+N Sbjct: 654 NGDPQR-VFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDGTSTATVNIVVTDVN 711 Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741 D+ PVF+ +G+++A DPD G N VHYS+ G+ +N F + T Sbjct: 712 DNAPVFDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSL--GNFNNLFRI-TSN 768 Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQ 798 GS + T V L+ E R YELV+ A A P + + + I V D++DN+PV + Sbjct: 769 GS----IYTAVKLNRE-VRDYYELVVVATDGAVHPRHSTLTLAIKVLDIDDNSPVFTNST 823 Query: 799 IIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 ++ P G ++ A D D+ + YRI S + L+ TG ++L L+ Sbjct: 824 YTV-LVEENLPAGTTILQIEAKDVDLGANVSYRIRSPEVKHFFALHPFTGELSLLRSLD 881 Score = 194 bits (474), Expect = 2e-47 Identities = 205/658 (31%), Positives = 297/658 (45%), Gaps = 81/658 (12%) Query: 11 INVLDCNDHSPV-FEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 I VL N+ SP F Y + E G +L L+ATD++ + Y IE Sbjct: 603 IEVLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATDRE---GDSITYAIE------ 653 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N + Q VF + +G L +LDRE RY +++ A+D P Sbjct: 654 -NGDP------------QRVFNLSETTGILTLGKALDRESTDRYILIITASD-GRPDG-- 697 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKT-YTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 +STAT+++ + D NDN P F +SV E+ + N + ++KATD D G N + Sbjct: 698 -TSTATVNIVVTDVNDNAPVFDPYLPRNLSVVEEEA---NAFVGQVKATDPDAGINGQVH 753 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y++ GN F I S +G + L+ E Y LV+ A DG R +T L I + Sbjct: 754 YSL--GNFNNLFRITS-NGSIYTAVKLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVL 810 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D++DN+P F S + V EN+P G +I++++A D D G N ++Y + + V Sbjct: 811 DIDDNSPVFTNSTYTVLVEENLPAGTTILQIEAKDVDLGAN--VSYRIRSPE----VKHF 864 Query: 309 ITIDPRSGWVYTSGQLDRET----QAKYQLLVTATD--GGDPPRSATATXXXXXXXXXXX 362 + P +G + LD E +A LV A D G PP AT T Sbjct: 865 FALHPFTGELSLLRSLDYEAFPDQEASITFLVEAFDIYGTMPPGIATVT--VIVKDMNDY 922 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADED----NRLHYEITGGN---TRGRFSIT 415 F Y+ +A D GTP+ T+ A DAD +R+ Y + F + Sbjct: 923 PPVFSKRIYKGMVAPDAVKGTPITTVYAEDADPPGLPASRVRYRVDDVQFPYPASIFEVE 982 Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAP 473 +GR + V L+ + + L V A D G S +A V+I + P F Sbjct: 983 EDSGRVITRV--NLNEEPTTIFKLVVVAFDDGEPVMSSSATVKILVLHPGE-IPRFTQEE 1039 Query: 474 Y-TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 Y V E A GT V V+SA IN I YS+ S NE + F IN TG Sbjct: 1040 YRPPPVSELATKGTMVGVISA----AAINQSIVYSIVS--GNE-----EDTFGINNITGV 1088 Query: 533 ITTNKLLDRETMSGYLLTVTA-------RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585 I N LD ET + Y+L V A + VPS S+T V I + D N++ PVF+++ Sbjct: 1089 IYVNGPLDYETRTSYVLRVQADSLEVVLANLRVPSKSNTAKVYIEIQDENNHPPVFQKKF 1148 Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG--SFVIDPASGVIRT 641 Y + EDA + TSV +V ATD D G + Y L +EG FV++ +G+I+T Sbjct: 1149 YIGGVSEDARMFTSVLRVKATDKDTGNYSVMAYRLIIPPIKEGKEGFVVETYTGLIKT 1206 Score = 160 bits (388), Expect = 6e-37 Identities = 182/695 (26%), Positives = 296/695 (42%), Gaps = 65/695 (9%) Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR-----VQAYDADEGVNAELTYTM 296 ++ I +RD NDN+P F + +V+E P+G +I A D D+G N ++ Y + Sbjct: 132 EVRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVI 191 Query: 297 --TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG---DPPRSATAT 351 D T N I + +G + +L+ E + +Y +++ A D + R+ T T Sbjct: 192 QYNPDDPTSNDTFEIPL-MLTGNIVLRKRLNYEDKTRYFVIIQANDRAQNLNERRTTTTT 250 Query: 352 XXXXXXXXXXXXXXFMPG------------QYEVELAEDEPPG--TPVVTLTATDA-DED 396 F+P Y+ + E P P++ A D+D Sbjct: 251 LTVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIPELRTPEELNPIIVTPPIQAIDQD 310 Query: 397 NRLH---------YEITGGNTRGRFSITSQNGR-GLITVAQPLDFKQERRYVLTVSATDS 446 + Y I G + R +++ +P++ +++ L + A Sbjct: 311 RNIQPPSDRPGILYSILVGTPEDYPRFFHMHPRTAELSLLEPVNRDFHQKFDLVIKAEQD 370 Query: 447 GGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTV---LVVSATDSDVGIN 501 G A + I I D NN +P F Y + E AP+G T+ L +++ V ++ Sbjct: 371 NGHPLPAFAGLHIEILDENNQSPYFTMPSYQGYILESAPVGATISDSLNLTSPLRIVALD 430 Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGA---ITTNKLLDRETMSGYLLTVTARDGGV 558 I + E+ + + + F + QTG +T + +DRE Y ++TA DG Sbjct: 431 KDIEDTKDPEL-HLFLNDYTSVFTVT-QTGITRYLTLLQPVDREEQQTYTFSITAFDG-- 486 Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618 S+ V I V+D NDN P F + Y + D G SV Q+ A DAD G NG I Y Sbjct: 487 VQESEPVIVNIQVMDANDNTPTFPEISYDVYVYTDMRPGDSVIQLTAVDADEGSNGEITY 546 Query: 619 ELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678 E+ +G F+I+ +G+I ++ T+ L A D P + I + IE Sbjct: 547 EI--LVGAQGDFIINKTTGLITIAPGVEMIVGRTYALTVQAADNAPPAERRNSICTVYIE 604 Query: 679 DI---NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735 + N SPP F + ISE +G + ++A D EG + + Y+I+ GD F Sbjct: 605 VLPPNNQSPPRFPQLMYSLEISEAMRVGAVLLNLQATD-REGDS--ITYAIENGDPQRVF 661 Query: 736 SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--PPLWNDVRVEILVTDVNDNAPV 793 +L G L LD ES +Y L+I A+ P + V I+VTDVNDNAPV Sbjct: 662 NLSETTGI----LTLGKALDRES-TDRYILIITASDGRPDGTSTATVNIVVTDVNDNAPV 716 Query: 794 MKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSP 853 + + + G+V A D D Q GN NL + + GS+ + Sbjct: 717 FDPYLPRNLSVVEEEANAFVGQVKATDPDAGINGQVHYSLGNFNNLFRIT-SNGSIYTAV 775 Query: 854 QLNTNVPKLATMEVSVTDG-VNEIKAMMQLSVRLI 887 +LN V + V TDG V+ + + L+++++ Sbjct: 776 KLNREVRDYYELVVVATDGAVHPRHSTLTLAIKVL 810 Score = 49.2 bits (112), Expect = 0.002 Identities = 57/216 (26%), Positives = 93/216 (43%), Gaps = 19/216 (8%) Query: 619 ELDPKDREEGSFVIDPASGVI---RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH- 674 EL KD + ++DP ++ T + LDR+ V + + T+I H Sbjct: 74 ELSLKDNVDYWVLMDPVKQMLFLNSTGRVLDRDPPMNIHSIVVQVQC-INKKVGTIIYHE 132 Query: 675 --IKIEDINDSPPVFESDCLTFYISENSPIGTTI-----GEIRAHDPDEGPNAVVHYSIK 727 I + D ND+ P F+ + ++E +P+GTTI G+ A D D+GPN + Y I+ Sbjct: 133 VRIVVRDRNDNSPTFKHESYYATVNELTPVGTTIFTGFSGDNGATDIDDGPNGQIEYVIQ 192 Query: 728 -GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS-PPLWNDVR--VEIL 783 DD S +V L+YE + +Y ++I+A N+ R L Sbjct: 193 YNPDDPTSNDTFEIPLMLTGNIVLRKRLNYED-KTRYFVIIQANDRAQNLNERRTTTTTL 251 Query: 784 VTDVNDNAPVMKDFQ--IIFNNYKDCFPVGPFGRVP 817 DV D + F ++ N +DC P+ +P Sbjct: 252 TVDVLDGDDLGPMFLPCVLVPNTRDCRPLTYQAAIP 287 >UniRef50_UPI0000F2053F Cluster: PREDICTED: similar to FAT tumor suppressor homolog 1 (Drosophila),; n=3; Danio rerio|Rep: PREDICTED: similar to FAT tumor suppressor homolog 1 (Drosophila), - Danio rerio Length = 1402 Score = 268 bits (658), Expect = 1e-69 Identities = 241/782 (30%), Positives = 374/782 (47%), Gaps = 98/782 (12%) Query: 104 SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI 163 +++ E+ + YTVL+ +D + A++ V ++D NDN P+F + TVS+ E+ Sbjct: 479 TVETEEKSSYTVLLSISDGTN------RDEASVLVEVLDVNDNSPEFEDHPPTVSISENH 532 Query: 164 SVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY 223 V ++ +A +KATDAD G N+ ++Y ++GG + F+ID +G ++L LD E Y Sbjct: 533 IVGED--VASVKATDADAGFNAEVQYTLLGGAGR--FNIDQETGVITLAAPLDREAQDEY 588 Query: 224 RLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYD 283 LVI QD G PS S TT L I + D+NDN+P F ++ ++ E+ +G +V V A D Sbjct: 589 HLVITVQDQGRPSLSTTTDLGITVTDINDNSPIFSKQQYETTMFEDADVGADVVVVMATD 648 Query: 284 ADEGVNAELTYTMTDKDYTGNVDLPI-TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG 342 D+GVNA +++ + ++ + D P+ ID SG V +G+LD +Y L V DGG Sbjct: 649 KDDGVNAVVSFHIVNQQPSS--DTPVFNIDSDSGSVTLAGKLDYSKAKRYTLDVEGRDGG 706 Query: 343 DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYE 402 P + +A VE D+PP + + D ++ Sbjct: 707 SPSLTGSAVVIVW-----------------VEDVNDKPP-------VFSKDEYDVSIYEN 742 Query: 403 ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDA 462 + GG +T ++ ++ V QP+D G TA V I + D Sbjct: 743 LAGGTALVSLEVTDEDK--VVAVDQPVD-----------------GLRSTAQVIITVLDI 783 Query: 463 NNYAPVFENAPYTASVFEDAPIGTT---VLVVSATDSDVGINAQITYSLSSEISNEAVAH 519 N+ P F P + E ++ V +SATD+D+G N +T+S SS Sbjct: 784 NDNNPQFLPLPELIEIQEGKYTQSSPGEVCKISATDADIGDNGLVTFSTSSY-------- 835 Query: 520 HDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP 579 +F G + LDRE Y + +TA D G+P L++ T V +S+ DVNDN P Sbjct: 836 --SKFFSCSDDGTLQAISELDREMQDVYDVVITAVDHGIPQLNNMTTVRVSITDVNDNAP 893 Query: 580 VFKQQLYTANIM-EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV-IDPASG 637 VF + Y+ +I+ DA VG + V ATD D G N I Y E S V +D +G Sbjct: 894 VFSSETYSRSILVRDAKVGELLLTVSATDRDAGDNALITYSFS----EVSSMVALDAETG 949 Query: 638 VIRTNKALDRESVAT-HDLKAVAIDGGTPPQS--STVIVHIKIEDINDSPPVFESDCLTF 694 I L + T L A+A D GTP S + V++H KI +++S FES F Sbjct: 950 DITLTSDLSEVTEDTLLTLSAIATDHGTPALSDEAEVLIHFKIASLSESVS-FESSSYNF 1008 Query: 695 YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDL 754 I EN P T +G ++A P V+Y++K +D FS++ +G+ +A L ++ Sbjct: 1009 MIKENEPEETIVGTVKA--LTGSPLVTVNYNMKSHED--VFSVDA-EGTIQA-LKSLDKE 1062 Query: 755 DYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP---VMKDFQIIFNNYKDCFPVG 811 D E E I + +PP + V + V +VN+ AP K IFN FP+ Sbjct: 1063 DVEWYILTVE-AIDSRTPPNTAETTVSVQVENVNE-APEFDAEKYTAEIFNIAPYKFPI- 1119 Query: 812 PFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSV 869 +V A D DV + KLQY ++ ++ + +TG + + ++ V L T EV Sbjct: 1120 --VKVQATDPDVDESSKLQYSLV--KPTTVLDVEASTGQLYVL-DASSIVDPLVTYEVKA 1174 Query: 870 TD 871 TD Sbjct: 1175 TD 1176 Score = 192 bits (467), Expect = 2e-46 Identities = 187/685 (27%), Positives = 316/685 (46%), Gaps = 75/685 (10%) Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266 G++ L+K L+Y ++ Y ++AQD G S+TT + I I D ++ P F SL++ ++ Sbjct: 77 GNIRLLKHLNYNNIQQYTFTVKAQDTG--GLSDTTAVTITIVDYDNLNPYFDHSLYKATI 134 Query: 267 SENVPIGYSIV---RVQAYDADEGVNAELTYTMT---DKDYTGNVDLPITIDPRSGWVYT 320 EN +S V ++A D D G+N + Y++T +Y N + I+P SG + Sbjct: 135 EENEIGHFSDVTPEAIKAQDGDTGINEPVVYSLTTVLPNEYQSNFE----INPNSGVISV 190 Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380 + LDRE + L + A DP ++A A F +Y + + E+ P Sbjct: 191 TTALDREEIDQITLYIQAAQQNDPSKTANAVVSVIIEDVDDNSPKFDQEEYIISIPENSP 250 Query: 381 PGTPVVTLTATDADEDNRL-HYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL 439 V+ TD D + I + FSI + +GR L+ + LD + + Sbjct: 251 KDQFVLQTIVTDLDLGGFVGTLRIIPDSV--PFSI-NPDGRILVKRPEDLDRETTAIFSF 307 Query: 440 TVSATDS--GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497 V A ++ +TA V I + D N+ +P F ++ Y V+ D +G V+ V ATD D Sbjct: 308 QVEAQENPPSTNKETADVTIILLDENDNSPQFTDSEYEGKVYADQTVGMEVVKVEATDLD 367 Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL--LDRETMSGYLLTVTARD 555 G NA+I+Y + E NE F +N + GAIT +L L + + L +TARD Sbjct: 368 EGPNAEISYFI--EFGNE-----KGFFGLNEKDGAITLVQLIPLVENEILEFALYITARD 420 Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615 GG ++S +T + + D+ P F Q+ Y + E+ DA++ + Sbjct: 421 GG--AISRSTPALVHIQAPGDSHPQFLQKTYQGQVEEN-----------QEDAEI---VK 464 Query: 616 IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675 +++ IDP V T + ++ S ++I GT ++V+V Sbjct: 465 VNF-----------LSIDPFVPVTLTVETEEKSSYTV----LLSISDGTNRDEASVLV-- 507 Query: 676 KIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735 ++ D+ND+ P FE T ISEN +G + ++A D D G NA V Y++ GG + F Sbjct: 508 EVLDVNDNSPEFEDHPPTVSISENHIVGEDVASVKATDADAGFNAEVQYTLLGG--AGRF 565 Query: 736 SLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792 +++ G + LD E+ + +Y LVI P L + I VTD+NDN+P Sbjct: 566 NIDQETG----VITLAAPLDREA-QDEYHLVITVQDQGRPSLSTTTDLGITVTDINDNSP 620 Query: 793 VMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILS---GNNANLILLNETTG 847 + Q ++D V A D D V + + I++ ++ + ++ +G Sbjct: 621 IFSKQQYETTMFEDADVGADVVVVMATDKDDGVNAVVSFHIVNQQPSSDTPVFNIDSDSG 680 Query: 848 SMTLSPQLNTNVPKLATMEVSVTDG 872 S+TL+ +L+ + K T++V DG Sbjct: 681 SVTLAGKLDYSKAKRYTLDVEGRDG 705 Score = 177 bits (431), Expect = 4e-42 Identities = 103/296 (34%), Positives = 152/296 (51%), Gaps = 12/296 (4%) Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 + V ++ +++ Y + +S +D R D A V + + D N+ +P FE+ P T S+ E+ Sbjct: 474 VPVTLTVETEEKSSYTVLLSISDGTNR-DEASVLVEVLDVNDNSPEFEDHPPTVSISENH 532 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 +G V V ATD+D G NA++ Y+L +F I+ +TG IT LDRE Sbjct: 533 IVGEDVASVKATDADAGFNAEVQYTLLGGAG---------RFNIDQETGVITLAAPLDRE 583 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 Y L +T +D G PSLS TTD+ I+V D+NDN P+F +Q Y + EDA VG V Sbjct: 584 AQDEYHLVITVQDQGRPSLSTTTDLGITVTDINDNSPIFSKQQYETTMFEDADVGADVVV 643 Query: 603 VGATDADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 V ATD D G+N + + + + F ID SG + LD + L Sbjct: 644 VMATDKDDGVNAVVSFHIVNQQPSSDTPVFNIDSDSGSVTLAGKLDYSKAKRYTLDVEGR 703 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 DGG+P + + +V + +ED+ND PPVF D I EN GT + + D D+ Sbjct: 704 DGGSPSLTGSAVVIVWVEDVNDKPPVFSKDEYDVSIYENLAGGTALVSLEVTDEDK 759 Score = 144 bits (349), Expect = 3e-32 Identities = 95/281 (33%), Positives = 142/281 (50%), Gaps = 29/281 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND+SP FE S+ E G V ++KATD D G NAEV+YT+ L A Sbjct: 507 VEVLDVNDNSPEFEDHPPTVSISENHIVGEDVASVKATDADAGFNAEVQYTL-LGGAGRF 565 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N ID +G + A LDRE Y +++ DQ P L Sbjct: 566 N--------------------IDQETGVITLAAPLDREAQDEYHLVITVQDQGRP---SL 602 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+T + + + D NDN P FS++ Y ++ ED V + V+ + ATD D G N+ + + Sbjct: 603 STTTDLGITVTDINDNSPIFSKQQYETTMFEDADVGADVVV--VMATDKDDGVNAVVSFH 660 Query: 191 IIGGNTQMQ---FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 I+ F+IDS SG V+L LDY + + Y L + +DGGSPS + + +++ + Sbjct: 661 IVNQQPSSDTPVFNIDSDSGSVTLAGKLDYSKAKRYTLDVEGRDGGSPSLTGSAVVIVWV 720 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV 288 DVND P F + S+ EN+ G ++V ++ D D+ V Sbjct: 721 EDVNDKPPVFSKDEYDVSIYENLAGGTALVSLEVTDEDKVV 761 Score = 126 bits (304), Expect = 9e-27 Identities = 112/422 (26%), Positives = 174/422 (41%), Gaps = 21/422 (4%) Query: 66 TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125 T T+ P DA DV R DG L L+ + +YT VKA D Sbjct: 50 TVRTIKPLDADEIKQPPAPEDFDV-RSDGNIRLL---KHLNYNNIQQYTFTVKAQDTGG- 104 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE-DISVTDNPVIAKIKATDADVGAN 184 LS T + + I+D ++ P F Y +++E +I + IKA D D G N Sbjct: 105 ----LSDTTAVTITIVDYDNLNPYFDHSLYKATIEENEIGHFSDVTPEAIKAQDGDTGIN 160 Query: 185 SAIRYA---IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 + Y+ ++ Q F I+ SG +S+ LD E++ L I+A PS++ Sbjct: 161 EPVVYSLTTVLPNEYQSNFEINPNSGVISVTTALDREEIDQITLYIQAAQQNDPSKTANA 220 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 + + I DV+DN+P+F + S+ EN P +++ D D G + T + Sbjct: 221 VVSVIIEDVDDNSPKFDQEEYIISIPENSPKDQFVLQTIVTDLDLG-----GFVGTLRII 275 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 +V I D R V LDRET A + V A + TA Sbjct: 276 PDSVPFSINPDGRI-LVKRPEDLDRETTAIFSFQVEAQENPPSTNKETADVTIILLDEND 334 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNG 419 F +YE ++ D+ G VV + ATD DE + + Y I GN +G F + ++G Sbjct: 335 NSPQFTDSEYEGKVYADQTVGMEVVKVEATDLDEGPNAEISYFIEFGNEKGFFGLNEKDG 394 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479 + PL + + L ++A D G S + ++I + P F Y V Sbjct: 395 AITLVQLIPLVENEILEFALYITARDGGAISRSTPALVHIQAPGDSHPQFLQKTYQGQVE 454 Query: 480 ED 481 E+ Sbjct: 455 EN 456 Score = 113 bits (271), Expect = 9e-23 Identities = 108/378 (28%), Positives = 163/378 (43%), Gaps = 20/378 (5%) Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 P+ L + TD D+ + L ++ + A D F + G I K L+ Sbjct: 32 PVALDFLELVYTDGDLNATVRTIKPLDADEIKQPPAPED--FDVRSD-GNIRLLKHLNYN 88 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL---VGTS 599 + Y TV A+D G LSDTT V I++VD ++ P F LY A I E+ + + Sbjct: 89 NIQQYTFTVKAQDTG--GLSDTTAVTITIVDYDNLNPYFDHSLYKATIEENEIGHFSDVT 146 Query: 600 VSQVGATDADVGLNGRIHYELDP--KDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 + A D D G+N + Y L + + +F I+P SGVI ALDRE + L Sbjct: 147 PEAIKAQDGDTGINEPVVYSLTTVLPNEYQSNFEINPNSGVISVTTALDREEIDQITLYI 206 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A P +++ +V + IED++D+ P F+ + I ENSP + + D D G Sbjct: 207 QAAQQNDPSKTANAVVSVIIEDVDDNSPKFDQEEYIISIPENSPKDQFVLQTIVTDLDLG 266 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN- 776 +++ DS FS+ + + DLD E+ V +PP N Sbjct: 267 GFV---GTLRIIPDSVPFSINP---DGRILVKRPEDLDRETTAIFSFQVEAQENPPSTNK 320 Query: 777 -DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILS 833 V I++ D NDN+P D + Y D +V A D D ++ Y I Sbjct: 321 ETADVTIILLDENDNSPQFTDSEYEGKVYADQTVGMEVVKVEATDLDEGPNAEISYFIEF 380 Query: 834 GNNANLILLNETTGSMTL 851 GN LNE G++TL Sbjct: 381 GNEKGFFGLNEKDGAITL 398 Score = 110 bits (265), Expect = 5e-22 Identities = 101/346 (29%), Positives = 163/346 (47%), Gaps = 34/346 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVRE---GASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 I ++D ++ +P F+ Y+A++ E G S T +KA D D G N V Y++ Sbjct: 113 ITIVDYDNLNPYFDHSLYKATIEENEIGHFSDVTPEAIKAQDGDTGINEPVVYSLT---- 168 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 T+ P + Q F I+ SG + +LDRE++ + T+ ++A Q P Sbjct: 169 -TVLPNE-----------YQSNFEINPNSGVISVTTALDREEIDQITLYIQAAQQNDPSK 216 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 ++ A + V I D +DN P+F ++ Y +S+ E+ S D V+ I TD D+G Sbjct: 217 ---TANAVVSVIIEDVDDNSPKFDQEEYIISIPEN-SPKDQFVLQTI-VTDLDLGGFVGT 271 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 I + FSI+ G + LVK LD E + + AQ+ + T + Sbjct: 272 LRII---PDSVPFSINP-DGRI-LVKRPEDLDRETTAIFSFQVEAQENPPSTNKETADVT 326 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 I + D NDN+P+F S ++ V + +G +V+V+A D DEG NAE++Y + + G Sbjct: 327 IILLDENDNSPQFTDSEYEGKVYADQTVGMEVVKVEATDLDEGPNAEISYFIEFGNEKGF 386 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350 L D V ++ E ++ L +TA DGG RS A Sbjct: 387 FGLN-EKDGAITLVQLIPLVENEI-LEFALYITARDGGAISRSTPA 430 Score = 106 bits (255), Expect = 8e-21 Identities = 125/473 (26%), Positives = 195/473 (41%), Gaps = 54/473 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGA---SSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 I VLD ND++P F ++EG SS V + ATD DIG N LVT Sbjct: 778 ITVLDINDNNPQFLPLPELIEIQEGKYTQSSPGEVCKISATDADIGDNG-------LVTF 830 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 T + F G L + LDRE Y V++ A D P Sbjct: 831 STSS---------------YSKFFSCSDDGTLQAISELDREMQDVYDVVITAVDHGIP-- 873 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSV-DEDISVTDNPVIAKIKATDADVGANSA 186 +L++ T+ V+I D NDN P FS +TY+ S+ D V + ++ + ATD D G N+ Sbjct: 874 -QLNNMTTVRVSITDVNDNAPVFSSETYSRSILVRDAKVGE--LLLTVSATDRDAGDNAL 930 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTL-DYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 I Y+ ++D+ +GD++L L + + L A D G+P+ S+ ++LI Sbjct: 931 ITYSF--SEVSSMVALDAETGDITLTSDLSEVTEDTLLTLSAIATDHGTPALSDEAEVLI 988 Query: 246 NIRDVN-DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + + + + F +S + + EN P + V+A V + Y M + + Sbjct: 989 HFKIASLSESVSFESSSYNFMIKENEPEETIVGTVKALTGSPLVT--VNYNMKSHEDVFS 1046 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 VD G + LD+E Y L V A D PP +A T Sbjct: 1047 VDA-------EGTIQALKSLDKEDVEWYILTVEAIDSRTPPNTA-ETTVSVQVENVNEAP 1098 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTAT--DADEDNRLHYEITGGNTRGRFSITSQNGRGL 422 F +Y E+ P P+V + AT D DE ++L Y + T + + G+ Sbjct: 1099 EFDAEKYTAEIFNIAPYKFPIVKVQATDPDVDESSKLQYSLVKPTT--VLDVEASTGQLY 1156 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINI--TDANNYAPVFENAP 473 + A + + V ATD G T V+I + + ++N + N P Sbjct: 1157 VLDASSI---VDPLVTYEVKATDKHGLFTTTAVEITVKQSASDNIVVISLNQP 1206 Score = 98.3 bits (234), Expect = 3e-18 Identities = 119/449 (26%), Positives = 176/449 (39%), Gaps = 36/449 (8%) Query: 267 SENVPIGYSIVRVQAYDADEGVNAEL-TYTMTDKDYTGNVDLPITIDPRS-GWVYTSGQL 324 S P+ + + D D +NA + T D D P D RS G + L Sbjct: 28 SHRFPVALDFLELVYTDGD--LNATVRTIKPLDADEIKQPPAPEDFDVRSDGNIRLLKHL 85 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 + +Y V A D G S T F Y+ + E+E Sbjct: 86 NYNNIQQYTFTVKAQDTGG--LSDTTAVTITIVDYDNLNPYFDHSLYKATIEENEIGHFS 143 Query: 385 VVTLTATDA-DEDNRLH----YEITG---GNTRGRFSITSQNGRGLITVAQPLDFKQERR 436 VT A A D D ++ Y +T + F I +G +I+V LD ++ + Sbjct: 144 DVTPEAIKAQDGDTGINEPVVYSLTTVLPNEYQSNFEINPNSG--VISVTTALDREEIDQ 201 Query: 437 YVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494 L + A S TA +V + I D ++ +P F+ Y S+ E++P VL T Sbjct: 202 ITLYIQAAQQNDPSKTANAVVSVIIEDVDDNSPKFDQEEYIISIPENSPKDQFVLQTIVT 261 Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL--LDRETMSGYLLTVT 552 D D+G + + F INP G I + LDRET + + V Sbjct: 262 DLDLG----------GFVGTLRIIPDSVPFSINPD-GRILVKRPEDLDRETTAIFSFQVE 310 Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612 A++ + +T DV I ++D NDN P F Y + D VG V +V ATD D G Sbjct: 311 AQENPPSTNKETADVTIILLDENDNSPQFTDSEYEGKVYADQTVGMEVVKVEATDLDEGP 370 Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNK--ALDRESVATHDLKAVAIDGGTPPQSST 670 N I Y ++ E+G F ++ G I + L + L A DGG +S+ Sbjct: 371 NAEISYFIE-FGNEKGFFGLNEKDGAITLVQLIPLVENEILEFALYITARDGGAISRSTP 429 Query: 671 VIVHIKIEDINDSPPVFESDCLTFYISEN 699 +VHI+ DS P F + EN Sbjct: 430 ALVHIQAP--GDSHPQFLQKTYQGQVEEN 456 Score = 79.8 bits (188), Expect = 1e-12 Identities = 72/289 (24%), Positives = 132/289 (45%), Gaps = 33/289 (11%) Query: 10 QINVLDCNDHSPVFEMQQYEASVR-EGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68 ++++ D ND++PVF + Y S+ A G +LT+ ATD+D G NA + Y+ V+ Sbjct: 882 RVSITDVNDNAPVFSSETYSRSILVRDAKVGELLLTVSATDRDAGDNALITYSFSEVS-- 939 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP-VS 127 ++ DA + +V LLT +++ ATD +P +S Sbjct: 940 SMVALDAETGDITLTSDLSEV-----TEDTLLTLSAI-------------ATDHGTPALS 981 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 D + IH I +++ F +Y + E + + ++ +KA + Sbjct: 982 D--EAEVLIHFKIASLSESV-SFESSSYNFMIKE--NEPEETIVGTVKALTG--SPLVTV 1034 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 Y + + + FS+D+ G + +K+LD E V Y L + A D +P + T + + + Sbjct: 1035 NYNM--KSHEDVFSVDA-EGTIQALKSLDKEDVEWYILTVEAIDSRTPPNTAETTVSVQV 1091 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 +VN+ AP F + + P + IV+VQA D D +++L Y++ Sbjct: 1092 ENVNE-APEFDAEKYTAEIFNIAPYKFPIVKVQATDPDVDESSKLQYSL 1139 >UniRef50_UPI00006A1F6A Cluster: UPI00006A1F6A related cluster; n=3; Xenopus tropicalis|Rep: UPI00006A1F6A UniRef100 entry - Xenopus tropicalis Length = 644 Score = 260 bits (638), Expect = 3e-67 Identities = 190/601 (31%), Positives = 286/601 (47%), Gaps = 46/601 (7%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +F I+ +G++ T +++DRE L+ +S + + + + ++D NDN P Sbjct: 66 LFSINSTTGSIYTTSNIDRES------LISDVINLVVLSSQPTYPTEVRITVLDINDNSP 119 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI------ 202 F E V + ED+ I + A+D D G N+ +RY+I+ GN FSI Sbjct: 120 VFQEPHSKVEISEDLP--PGSYICGVSASDGDTGLNANLRYSIVSGNKLGWFSISENSGL 177 Query: 203 -DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261 D LSG +S LD EQ L I A D G+P S+T ++++++ DVNDN+P FY Sbjct: 178 LDPLSGKLSNRADLDREQQDRCTLQILATDLGTPPLSSTAKVIVSLLDVNDNSPVFYPVQ 237 Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321 + ++ EN P + V A D D G+N + Y++ D + + P +G + T Sbjct: 238 YFANIQENEPPASFVATVTASDPDLGINGTIRYSIRAGDTS-----KFQVHPETGAISTK 292 Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE-VELAEDEP 380 LDRE + YQL V ATDGG A F G Y ++E Sbjct: 293 AALDREEKTAYQLQVVATDGGGLQSHNHAIVTITVLDTQDNPPSFSQGSYSFASISELAS 352 Query: 381 PGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYV 438 T V+ ++++D DE N + Y I GN F++ S G+ + + LD++ Y Sbjct: 353 NMTQVLRVSSSDVDEGNNGLISYSIMKGNEEKHFTMDSSTGQ--VALVGRLDYEATASYS 410 Query: 439 LTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496 L + A DSG S T+ + I + D N+ +P F A V E+ +G V V+ATDS Sbjct: 411 LIIQAVDSGAVPLSATSTLSIEVLDENDNSPSFPKAALFVDVVENMRVGELVSSVTATDS 470 Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556 D G NA I YS++ ++ F I+P TG+I K LD ET + Y L +TA+D Sbjct: 471 DSGDNADIHYSITG-------TNNHGTFSISPNTGSIFLAKKLDFETQALYKLNITAKDK 523 Query: 557 GVPSLSDTTDVEISVVDVNDNEPVF-------KQQLYTANIMEDALVGTSVSQVGATDAD 609 G P S T V I V D NDN P F Q + A+ +G+ +S + A D D Sbjct: 524 GNPPRSSTMSVIIKVRDFNDNPPSFPAVPTFVSQNAFAAD--PSLAIGSVLSTITAFDPD 581 Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669 G NG I YE+ D E +F++D SG +R + S + L A D G +++ Sbjct: 582 EGSNGEIEYEIISGDTE--TFIVDRYSGDLRVAAPM-LPSHLIYSLIVAATDLGAERKAT 638 Query: 670 T 670 T Sbjct: 639 T 639 Score = 241 bits (591), Expect = 1e-61 Identities = 186/592 (31%), Positives = 289/592 (48%), Gaps = 45/592 (7%) Query: 310 TIDPRSGWVYTSGQLDRETQAKYQL-LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 +I+ +G +YT+ +DRE+ + LV + P T F Sbjct: 68 SINSTTGSIYTTSNIDRESLISDVINLVVLSSQPTYPTEVRITVLDINDNSPV----FQE 123 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNG-----RG 421 +VE++ED PPG+ + ++A+D D + L Y I GN G FSI+ +G G Sbjct: 124 PHSKVEISEDLPPGSYICGVSASDGDTGLNANLRYSIVSGNKLGWFSISENSGLLDPLSG 183 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVF 479 ++ LD +Q+ R L + ATD G S TA V +++ D N+ +PVF Y A++ Sbjct: 184 KLSNRADLDREQQDRCTLQILATDLGTPPLSSTAKVIVSLLDVNDNSPVFYPVQYFANIQ 243 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E+ P + V V+A+D D+GIN I YS+ A +F ++P+TGAI+T L Sbjct: 244 ENEPPASFVATVTASDPDLGINGTIRYSIR--------AGDTSKFQVHPETGAISTKAAL 295 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT-ANIMEDALVGT 598 DRE + Y L V A DGG + V I+V+D DN P F Q Y+ A+I E A T Sbjct: 296 DREEKTAYQLQVVATDGGGLQSHNHAIVTITVLDTQDNPPSFSQGSYSFASISELASNMT 355 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 V +V ++D D G NG I Y + K EE F +D ++G + LD E+ A++ L Sbjct: 356 QVLRVSSSDVDEGNNGLISYSI-MKGNEEKHFTMDSSTGQVALVGRLDYEATASYSLIIQ 414 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 A+D G P S+T + I++ D ND+ P F L + EN +G + + A D D G Sbjct: 415 AVDSGAVPLSATSTLSIEVLDENDNSPSFPKAALFVDVVENMRVGELVSSVTATDSDSGD 474 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLW 775 NA +HYSI G ++ +FS+ GS + LD+E+ + Y+L I A +PP Sbjct: 475 NADIHYSITGTNNHGTFSISPNTGS----IFLAKKLDFET-QALYKLNITAKDKGNPPRS 529 Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-------FGRVPAYDAD--VTDK 826 + + V I V D NDN P + ++ F P + A+D D + Sbjct: 530 STMSVIIKVRDFNDNPPSFPAVPTFVS--QNAFAADPSLAIGSVLSTITAFDPDEGSNGE 587 Query: 827 LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKA 878 ++Y I+SG+ I+ + +P L +++ + ++ V+ TD E KA Sbjct: 588 IEYEIISGDTETFIVDRYSGDLRVAAPMLPSHL--IYSLIVAATDLGAERKA 637 Score = 241 bits (591), Expect = 1e-61 Identities = 182/571 (31%), Positives = 277/571 (48%), Gaps = 45/571 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I VLD ND+SPVF+ + + E G+ + + A+D D G NA + Y+I V+ + Sbjct: 108 RITVLDINDNSPVFQEPHSKVEISEDLPPGSYICGVSASDGDTGLNANLRYSI--VSGNK 165 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L ++ +D SG L RA LDRE+ R T+ + ATD +P Sbjct: 166 LG----------WFSISENSGLLDPLSGKLSNRADLDREQQDRCTLQILATDLGTP---P 212 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LSSTA + V+++D NDN P F Y ++ E+ +A + A+D D+G N IRY Sbjct: 213 LSSTAKVIVSLLDVNDNSPVFYPVQYFANIQENEPPAS--FVATVTASDPDLGINGTIRY 270 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 +I G+T +F + +G +S LD E+ +Y+L + A DGG N + I + D Sbjct: 271 SIRAGDTS-KFQVHPETGAISTKAALDREEKTAYQLQVVATDGGGLQSHNHAIVTITVLD 329 Query: 250 VNDNAPRFYTSLFQ-ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 DN P F + S+SE ++RV + D DEG N ++Y++ GN + Sbjct: 330 TQDNPPSFSQGSYSFASISELASNMTQVLRVSSSDVDEGNNGLISYSI----MKGNEEKH 385 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 T+D +G V G+LD E A Y L++ A D G P SAT+T F Sbjct: 386 FTMDSSTGQVALVGRLDYEATASYSLIIQAVDSGAVPLSATSTLSIEVLDENDNSPSFPK 445 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADE-DNR-LHYEITGGNTRGRFSITSQNGRGLITVA 426 V++ E+ G V ++TATD+D DN +HY ITG N G FSI+ G I +A Sbjct: 446 AALFVDVVENMRVGELVSSVTATDSDSGDNADIHYSITGTNNHGTFSISPNTGS--IFLA 503 Query: 427 QPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAP--YTASVFEDA 482 + LDF+ + Y L ++A D G RS T V I + D N+ P F P + + F Sbjct: 504 KKLDFETQALYKLNITAKDKGNPPRSSTMSVIIKVRDFNDNPPSFPAVPTFVSQNAFAAD 563 Query: 483 P---IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKL 538 P IG+ + ++A D D G N +I Y E ++ + F+++ +G + + Sbjct: 564 PSLAIGSVLSTITAFDPDEGSNGEIEY--------EIISGDTETFIVDRYSGDLRVAAPM 615 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569 L + Y L V A D G + TT++ I Sbjct: 616 LPSHLI--YSLIVAATDLGAERKATTTELTI 644 Score = 214 bits (522), Expect = 3e-53 Identities = 156/508 (30%), Positives = 243/508 (47%), Gaps = 25/508 (4%) Query: 374 ELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ 433 ++ E++PPGT V T++ + + FSI S G I +D + Sbjct: 36 QVLEEQPPGTYVGTISTKPGFTYRLSEFHVL-------FSINSTTGS--IYTTSNIDRES 86 Query: 434 ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 V+ + S T V+I + D N+ +PVF+ + ED P G+ + VSA Sbjct: 87 LISDVINLVVLSSQPTYPTE-VRITVLDINDNSPVFQEPHSKVEISEDLPPGSYICGVSA 145 Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553 +D D G+NA + YS+ S + + +++P +G ++ LDRE L + A Sbjct: 146 SDGDTGLNANLRYSIVSGNKLGWFSISENSGLLDPLSGKLSNRADLDREQQDRCTLQILA 205 Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613 D G P LS T V +S++DVNDN PVF Y ANI E+ + V+ V A+D D+G+N Sbjct: 206 TDLGTPPLSSTAKVIVSLLDVNDNSPVFYPVQYFANIQENEPPASFVATVTASDPDLGIN 265 Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673 G I Y + D + F + P +G I T ALDRE + L+ VA DGG + IV Sbjct: 266 GTIRYSIRAGDTSK--FQVHPETGAISTKAALDREEKTAYQLQVVATDGGGLQSHNHAIV 323 Query: 674 HIKIEDINDSPPVFESDCLTF-YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732 I + D D+PP F +F ISE + T + + + D DEG N ++ YSI G++ Sbjct: 324 TITVLDTQDNPPSFSQGSYSFASISELASNMTQVLRVSSSDVDEGNNGLISYSIMKGNEE 383 Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVND 789 F++++ G ++ + LDYE+ Y L+I+A + PL + I V D ND Sbjct: 384 KHFTMDSSTG----QVALVGRLDYEA-TASYSLIIQAVDSGAVPLSATSTLSIEVLDEND 438 Query: 790 NAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDK--LQYRILSGNNANLILLNETT 846 N+P +F + + VG V A D+D D + Y I NN ++ T Sbjct: 439 NSPSFPK-AALFVDVVENMRVGELVSSVTATDSDSGDNADIHYSITGTNNHGTFSISPNT 497 Query: 847 GSMTLSPQLNTNVPKLATMEVSVTDGVN 874 GS+ L+ +L+ L + ++ D N Sbjct: 498 GSIFLAKKLDFETQALYKLNITAKDKGN 525 >UniRef50_A6VVW9 Cluster: Autotransporter-associated beta strand repeat protein; n=2; cellular organisms|Rep: Autotransporter-associated beta strand repeat protein - Marinomonas sp. MWYL1 Length = 3391 Score = 260 bits (637), Expect = 4e-67 Identities = 265/903 (29%), Positives = 395/903 (43%), Gaps = 96/903 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTADT 69 ++V D ND++PV SV E A + T + T ATD D N+ + Y+ Sbjct: 2034 VSVNDLNDNTPVMTSGA-TGSVDENADTSTVIYTATATDADGTAANSTLVYS-------- 2084 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV--S 127 L+ +DA D ID +G + +AS D E Y+ V ATD + S Sbjct: 2085 LSGDDA------------DKLIIDATTGEVTLKASADYETQTSYSFNVVATDNGAGNFNS 2132 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSA 186 LS+T + V++ D NDN P + T SV+E+ + VI ATDAD ANS Sbjct: 2133 GSLSTTQAVIVSVNDLNDNTPVMTSGA-TGSVNENADTST--VIYTATATDADGTAANST 2189 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG-----SPSRSNTT 241 + Y++ G + + ID+ +G+V+L + DYE SY + A D G S S S T Sbjct: 2190 LVYSLSGDDAD-KLIIDATTGEVTLKASADYETQTSYSFNVVATDNGAGNFNSGSLSTTQ 2248 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKD 300 +++++ D+NDN P TS SV+EN I A DAD N L Y+++ D Sbjct: 2249 AVIVSVNDLNDNTP-VMTSGATGSVNENADTSTVIYTATATDADGTATNNTLRYSLSGDD 2307 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG----DPPRSATATXXXXX 356 + I+ +G V D ET++ Y V ATD G + +T Sbjct: 2308 AA-----LLDINAVTGVVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVIVS 2362 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFS 413 M + E+ T + T T TDAD +N L Y ++G + + Sbjct: 2363 VNDLNDNTPVMTSGATGSVDENADTSTVIYTATGTDADGTAANNTLRYSLSGDDA-DKLI 2421 Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATD-------SGGRSDTAMVQINITDANNYA 466 I + G +T+ D++ + Y V ATD SG S T V +++ D N+ Sbjct: 2422 IDATTGE--VTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNT 2479 Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFV 525 PV ++ T SV E+A T + +ATD+D N + YSLS + + A+ Sbjct: 2480 PVMTSSA-TGSVNENADTSTVIYTATATDADGTATNNTLRYSLSGD--DAALLD------ 2530 Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVP-----SLSDTTDVEISVVDVNDNEPV 580 IN TG +T D ET S Y V A D G SLS T V +SV D+NDN PV Sbjct: 2531 INAVTGVVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNAPV 2590 Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVI 639 TA+I E+A T V ATDAD N I + L D +F +D ++GV+ Sbjct: 2591 ITSGA-TASIDENAATSTVVYTATATDADGTSANNTISFSLTGTDA--AAFDVDSSTGVV 2647 Query: 640 RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699 + D E+ +++ +A D G + T V + + D+ND+ PV S T I EN Sbjct: 2648 TLKASADYETKSSYSFNVIATDNGAGNLTDTQAVIVSVNDLNDNAPVITSGA-TASIDEN 2706 Query: 700 SPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM-VDLDYE 757 + T + A D D N + +S+ G D+ +F +++ G +VT+ DYE Sbjct: 2707 AATSTVVYTATATDADGTSANNAISFSLTG-TDAAAFDIDSSTG-----VVTLKASADYE 2760 Query: 758 SPRKKYELVIRAA--------SPPLWNDVRVEILVTDVNDNAPVMKDFQI-IFNNYKDCF 808 + + Y + A S L V + V D+NDN PVM N D Sbjct: 2761 T-KASYSFNVVATDNGAGNFNSGSLSTTQAVIVSVNDLNDNTPVMTSGATGSVNENADTS 2819 Query: 809 PVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVS 868 V D + LSG++A+ ++++ TTG +TL + + V Sbjct: 2820 TVIYTATATDADGTAANSTLVYSLSGDDADKLIIDATTGEVTLKASADYETQTSYSFNVV 2879 Query: 869 VTD 871 TD Sbjct: 2880 ATD 2882 Score = 259 bits (635), Expect = 7e-67 Identities = 250/823 (30%), Positives = 369/823 (44%), Gaps = 91/823 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTADT 69 ++V D ND++PV SV E A + T + T ATD D N+ + Y+ Sbjct: 2143 VSVNDLNDNTPVMTSGA-TGSVNENADTSTVIYTATATDADGTAANSTLVYS-------- 2193 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV--S 127 L+ +DA D ID +G + +AS D E Y+ V ATD + S Sbjct: 2194 LSGDDA------------DKLIIDATTGEVTLKASADYETQTSYSFNVVATDNGAGNFNS 2241 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSA 186 LS+T + V++ D NDN P + T SV+E+ + VI ATDAD N+ Sbjct: 2242 GSLSTTQAVIVSVNDLNDNTPVMTSGA-TGSVNENADTST--VIYTATATDADGTATNNT 2298 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG-----SPSRSNTT 241 +RY++ G + + I++++G V+L + DYE SY + A D G S S S T Sbjct: 2299 LRYSLSGDDAAL-LDINAVTGVVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQ 2357 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKD 300 +++++ D+NDN P TS SV EN I DAD N L Y+++ D Sbjct: 2358 AVIVSVNDLNDNTP-VMTSGATGSVDENADTSTVIYTATGTDADGTAANNTLRYSLSGDD 2416 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG----DPPRSATATXXXXX 356 + ID +G V D ET++ Y V ATD G + +T Sbjct: 2417 AD-----KLIIDATTGEVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVS 2471 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFS 413 M + E+ T + T TATDAD +N L Y ++G + Sbjct: 2472 VNDLNDNTPVMTSSATGSVNENADTSTVIYTATATDADGTATNNTLRYSLSGDDA-ALLD 2530 Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATD-------SGGRSDTAMVQINITDANNYA 466 I + G ++T+ D++ + Y V ATD SG S T V +++ D N+ A Sbjct: 2531 INAVTG--VVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNA 2588 Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 PV + TAS+ E+A T V +ATD+D G +A T S S ++ A F + Sbjct: 2589 PVITSGA-TASIDENAATSTVVYTATATDAD-GTSANNTISFSLTGTDAAA------FDV 2640 Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586 + TG +T D ET S Y V A D G +L+DT V +SV D+NDN PV Sbjct: 2641 DSSTGVVTLKASADYETKSSYSFNVIATDNGAGNLTDTQAVIVSVNDLNDNAPVITSGA- 2699 Query: 587 TANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645 TA+I E+A T V ATDAD N I + L D +F ID ++GV+ + Sbjct: 2700 TASIDENAATSTVVYTATATDADGTSANNAISFSLTGTD--AAAFDIDSSTGVVTLKASA 2757 Query: 646 DRESVATHDLKAVAIDGG-----TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700 D E+ A++ VA D G + S+T V + + D+ND+ PV S T ++EN+ Sbjct: 2758 DYETKASYSFNVVATDNGAGNFNSGSLSTTQAVIVSVNDLNDNTPVMTSGA-TGSVNENA 2816 Query: 701 PIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759 T I A D D N+ + YS+ GDD++ ++ G E+ DYE+ Sbjct: 2817 DTSTVIYTATATDADGTAANSTLVYSL-SGDDADKLIIDATTG----EVTLKASADYET- 2870 Query: 760 RKKYELVIRAA--------SPPLWNDVRVEILVTDVNDNAPVM 794 + Y + A S L V + V D+NDN P + Sbjct: 2871 QTSYSFNVVATDNGAGNFNSGSLSTTQAVIVSVNDLNDNTPTV 2913 Score = 250 bits (611), Expect = 6e-64 Identities = 260/904 (28%), Positives = 391/904 (43%), Gaps = 98/904 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTADT 69 ++V D ND++PV SV E A + T + T TD D N + Y+ Sbjct: 1925 VSVNDLNDNTPVMTSGA-TGSVDENADTSTVIYTATGTDADGTATNNTLRYS-------- 1975 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV--S 127 L+ +DA D ID +G + +AS D E Y+ V ATD + S Sbjct: 1976 LSGDDA------------DKLIIDATTGEVTLKASADYETQTSYSFNVVATDNGAGNFNS 2023 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSA 186 LS+T + V++ D NDN P + T SVDE+ + VI ATDAD ANS Sbjct: 2024 GSLSTTQAVIVSVNDLNDNTPVMTSGA-TGSVDENADTST--VIYTATATDADGTAANST 2080 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG-----SPSRSNTT 241 + Y++ G + + ID+ +G+V+L + DYE SY + A D G S S S T Sbjct: 2081 LVYSLSGDDAD-KLIIDATTGEVTLKASADYETQTSYSFNVVATDNGAGNFNSGSLSTTQ 2139 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKD 300 +++++ D+NDN P TS SV+EN I A DAD N+ L Y+++ D Sbjct: 2140 AVIVSVNDLNDNTP-VMTSGATGSVNENADTSTVIYTATATDADGTAANSTLVYSLSGDD 2198 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG----DPPRSATATXXXXX 356 + ID +G V D ETQ Y V ATD G + +T Sbjct: 2199 AD-----KLIIDATTGEVTLKASADYETQTSYSFNVVATDNGAGNFNSGSLSTTQAVIVS 2253 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFS 413 M + E+ T + T TATDAD +N L Y ++G + Sbjct: 2254 VNDLNDNTPVMTSGATGSVNENADTSTVIYTATATDADGTATNNTLRYSLSGDDA-ALLD 2312 Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATD-------SGGRSDTAMVQINITDANNYA 466 I + G++T+ D++ + Y V ATD SG S T V +++ D N+ Sbjct: 2313 INAVT--GVVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVIVSVNDLNDNT 2370 Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFV 525 PV + T SV E+A T + + TD+D N + YSLS + ++ + + Sbjct: 2371 PVMTSGA-TGSVDENADTSTVIYTATGTDADGTAANNTLRYSLSGDDAD--------KLI 2421 Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGV-----PSLSDTTDVEISVVDVNDNEPV 580 I+ TG +T D ET S Y V A D G SLS T V +SV D+NDN PV Sbjct: 2422 IDATTGEVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNTPV 2481 Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVI 639 T ++ E+A T + ATDAD N + Y L D I+ +GV+ Sbjct: 2482 MTSSA-TGSVNENADTSTVIYTATATDADGTATNNTLRYSLSGDD--AALLDINAVTGVV 2538 Query: 640 RTNKALDRESVATHDLKAVAIDGG-----TPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694 + D E+ +++ +A D G + S+T V + + D+ND+ PV S T Sbjct: 2539 TLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNAPVITSGA-TA 2597 Query: 695 YISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM-V 752 I EN+ T + A D D N + +S+ G D+ +F +++ G +VT+ Sbjct: 2598 SIDENAATSTVVYTATATDADGTSANNTISFSLT-GTDAAAFDVDSSTG-----VVTLKA 2651 Query: 753 DLDYESPRKKYELVIRAASPPLWN--DVRVEIL-VTDVNDNAPVMKD--FQIIFNNYKDC 807 DYE+ + Y + A N D + I+ V D+NDNAPV+ I N Sbjct: 2652 SADYET-KSSYSFNVIATDNGAGNLTDTQAVIVSVNDLNDNAPVITSGATASIDENAATS 2710 Query: 808 FPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867 V A + + + L+G +A ++ +TG +TL + + V Sbjct: 2711 TVVYTATATDADGTSANNAISFS-LTGTDAAAFDIDSSTGVVTLKASADYETKASYSFNV 2769 Query: 868 SVTD 871 TD Sbjct: 2770 VATD 2773 Score = 241 bits (589), Expect = 3e-61 Identities = 258/909 (28%), Positives = 387/909 (42%), Gaps = 103/909 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTADT 69 ++V D ND++PV SV E A + T + T ATD D N + Y++ A Sbjct: 1816 VSVNDLNDNTPVMTSGA-TGSVNENADTSTVIYTATATDADGTATNNTLRYSLSGADAAL 1874 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV--S 127 L+ I+ +G + +AS D E + Y+ V ATD + S Sbjct: 1875 LD--------------------INAVTGVVTLKASADYETKSSYSFNVIATDNGAGNLNS 1914 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSA 186 LS+T + V++ D NDN P + T SVDE+ + VI TDAD N+ Sbjct: 1915 GSLSTTQAVTVSVNDLNDNTPVMTSGA-TGSVDENADTST--VIYTATGTDADGTATNNT 1971 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG-----SPSRSNTT 241 +RY++ G + + ID+ +G+V+L + DYE SY + A D G S S S T Sbjct: 1972 LRYSLSGDDAD-KLIIDATTGEVTLKASADYETQTSYSFNVVATDNGAGNFNSGSLSTTQ 2030 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKD 300 +++++ D+NDN P TS SV EN I A DAD N+ L Y+++ D Sbjct: 2031 AVIVSVNDLNDNTP-VMTSGATGSVDENADTSTVIYTATATDADGTAANSTLVYSLSGDD 2089 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG----DPPRSATATXXXXX 356 + ID +G V D ETQ Y V ATD G + +T Sbjct: 2090 AD-----KLIIDATTGEVTLKASADYETQTSYSFNVVATDNGAGNFNSGSLSTTQAVIVS 2144 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFS 413 M + E+ T + T TATDAD ++ L Y ++G + + Sbjct: 2145 VNDLNDNTPVMTSGATGSVNENADTSTVIYTATATDADGTAANSTLVYSLSGDDA-DKLI 2203 Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATD-------SGGRSDTAMVQINITDANNYA 466 I + G +T+ D++ + Y V ATD SG S T V +++ D N+ Sbjct: 2204 IDATTGE--VTLKASADYETQTSYSFNVVATDNGAGNFNSGSLSTTQAVIVSVNDLNDNT 2261 Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFV 525 PV + T SV E+A T + +ATD+D N + YSLS + + A+ Sbjct: 2262 PVMTSGA-TGSVNENADTSTVIYTATATDADGTATNNTLRYSLSGD--DAALLD------ 2312 Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGV-----PSLSDTTDVEISVVDVNDNEPV 580 IN TG +T D ET S Y V A D G SLS T V +SV D+NDN PV Sbjct: 2313 INAVTGVVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVIVSVNDLNDNTPV 2372 Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVI 639 T ++ E+A T + TDAD N + Y L D ++ +ID +G + Sbjct: 2373 MTSGA-TGSVDENADTSTVIYTATGTDADGTAANNTLRYSLSGDDADK--LIIDATTGEV 2429 Query: 640 RTNKALDRESVATHDLKAVAIDGG-----TPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694 + D E+ +++ +A D G + S+T V + + D+ND+ PV S T Sbjct: 2430 TLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNTPVMTSSA-TG 2488 Query: 695 YISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM-V 752 ++EN+ T I A D D N + YS+ GDD+ + G +VT+ Sbjct: 2489 SVNENADTSTVIYTATATDADGTATNNTLRYSL-SGDDAALLDINAVTG-----VVTLKA 2542 Query: 753 DLDYESPRKKYELVIRAA--------SPPLWNDVRVEILVTDVNDNAPVMKD--FQIIFN 802 DYE+ + Y + A S L V + V D+NDNAPV+ I Sbjct: 2543 SADYET-KSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNAPVITSGATASIDE 2601 Query: 803 NYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKL 862 N V A + + + L+G +A ++ +TG +TL + Sbjct: 2602 NAATSTVVYTATATDADGTSANNTISFS-LTGTDAAAFDVDSSTGVVTLKASADYETKSS 2660 Query: 863 ATMEVSVTD 871 + V TD Sbjct: 2661 YSFNVIATD 2669 Score = 235 bits (575), Expect = 1e-59 Identities = 241/873 (27%), Positives = 371/873 (42%), Gaps = 82/873 (9%) Query: 42 VLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLT 101 V+T AT ++ +NA I TA + + + I+ +GA+ Sbjct: 1509 VITSGATG-NVDENASTSTVIYTATATDADNDSLTYSLSGTDAAL---LNINASTGAVTL 1564 Query: 102 RASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE 161 + S D E Y+ + TD + S L+ + + V++ D ND+ P + T SV+E Sbjct: 1565 KNSADYETKNTYSFNIVVTDSS---SGHLTGSKAVTVSVNDLNDHTPVMTSGA-TGSVNE 1620 Query: 162 DISVTDNPVIAKIKATDAD-VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV 220 + + VI ATDAD N+ +RY++ G + + I+ ++G V+L + DYE Sbjct: 1621 NADT--STVIYTATATDADGTATNNTLRYSLSGADAAL-LDINVVTGVVTLKASADYETK 1677 Query: 221 RSYRLVIRAQDGG-----SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275 SY + A D G S S S T + +++ D+NDN P TS SV+EN Sbjct: 1678 SSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNTPAM-TSGATGSVNENADTSTV 1736 Query: 276 IVRVQAYDAD-EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQL 334 I A DAD N L Y+++ D + I+ +G V D ET++ Y Sbjct: 1737 IYTATATDADGTATNNTLRYSLSGADAA-----LLDINAVTGVVTLKASADYETKSSYSF 1791 Query: 335 LVTATDGG----DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTA 390 V ATD G + +T M + E+ T + T TA Sbjct: 1792 NVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNTPVMTSGATGSVNENADTSTVIYTATA 1851 Query: 391 TDAD---EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD-- 445 TDAD +N L Y ++G + I + G++T+ D++ + Y V ATD Sbjct: 1852 TDADGTATNNTLRYSLSGADA-ALLDINAVT--GVVTLKASADYETKSSYSFNVIATDNG 1908 Query: 446 -----SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VG 499 SG S T V +++ D N+ PV + T SV E+A T + + TD+D Sbjct: 1909 AGNLNSGSLSTTQAVTVSVNDLNDNTPVMTSGA-TGSVDENADTSTVIYTATGTDADGTA 1967 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV- 558 N + YSLS + ++ + +I+ TG +T D ET + Y V A D G Sbjct: 1968 TNNTLRYSLSGDDAD--------KLIIDATTGEVTLKASADYETQTSYSFNVVATDNGAG 2019 Query: 559 ----PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD-VGLN 613 SLS T V +SV D+NDN PV T ++ E+A T + ATDAD N Sbjct: 2020 NFNSGSLSTTQAVIVSVNDLNDNTPVMTSGA-TGSVDENADTSTVIYTATATDADGTAAN 2078 Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG-----TPPQS 668 + Y L D ++ +ID +G + + D E+ ++ VA D G + S Sbjct: 2079 STLVYSLSGDDADK--LIIDATTGEVTLKASADYETQTSYSFNVVATDNGAGNFNSGSLS 2136 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIK 727 +T V + + D+ND+ PV S T ++EN+ T I A D D N+ + YS+ Sbjct: 2137 TTQAVIVSVNDLNDNTPVMTSGA-TGSVNENADTSTVIYTATATDADGTAANSTLVYSL- 2194 Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA--------SPPLWNDVR 779 GDD++ ++ G E+ DYE+ + Y + A S L Sbjct: 2195 SGDDADKLIIDATTG----EVTLKASADYET-QTSYSFNVVATDNGAGNFNSGSLSTTQA 2249 Query: 780 VEILVTDVNDNAPVMKDFQI-IFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNAN 838 V + V D+NDN PVM N D V D T+ LSG++A Sbjct: 2250 VIVSVNDLNDNTPVMTSGATGSVNENADTSTVIYTATATDADGTATNNTLRYSLSGDDAA 2309 Query: 839 LILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 L+ +N TG +TL + + V TD Sbjct: 2310 LLDINAVTGVVTLKASADYETKSSYSFNVIATD 2342 Score = 212 bits (517), Expect = 1e-52 Identities = 215/770 (27%), Positives = 327/770 (42%), Gaps = 71/770 (9%) Query: 139 NIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQM 198 N I DN T +VDE+ S + VI ATDAD N ++ Y++ G + + Sbjct: 1498 NDITLKDNAAPVITSGATGNVDENASTST--VIYTATATDAD---NDSLTYSLSGTDAAL 1552 Query: 199 QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY 258 +I++ +G V+L + DYE +Y I D S + + + +++ D+ND+ P Sbjct: 1553 -LNINASTGAVTLKNSADYETKNTYSFNIVVTDSSSGHLTGSKAVTVSVNDLNDHTP-VM 1610 Query: 259 TSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317 TS SV+EN I A DAD N L Y+++ D +D+ + +G Sbjct: 1611 TSGATGSVNENADTSTVIYTATATDADGTATNNTLRYSLSGAD-AALLDINVV----TGV 1665 Query: 318 VYTSGQLDRETQAKYQLLVTATDGG----DPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373 V D ET++ Y V ATD G + +T M Sbjct: 1666 VTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNTPAMTSGATG 1725 Query: 374 ELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 + E+ T + T TATDAD +N L Y ++G + I + G++T+ D Sbjct: 1726 SVNENADTSTVIYTATATDADGTATNNTLRYSLSGADA-ALLDINAVT--GVVTLKASAD 1782 Query: 431 FKQERRYVLTVSATD-------SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 ++ + Y V ATD SG S T V +++ D N+ PV + T SV E+A Sbjct: 1783 YETKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNTPVMTSGA-TGSVNENAD 1841 Query: 484 IGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 T + +ATD+D N + YSLS ++ A+ IN TG +T D E Sbjct: 1842 TSTVIYTATATDADGTATNNTLRYSLSG--ADAALLD------INAVTGVVTLKASADYE 1893 Query: 543 TMSGYLLTVTARDGGV-----PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 T S Y V A D G SLS T V +SV D+NDN PV T ++ E+A Sbjct: 1894 TKSSYSFNVIATDNGAGNLNSGSLSTTQAVTVSVNDLNDNTPVMTSGA-TGSVDENADTS 1952 Query: 598 TSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 T + TDAD N + Y L D ++ +ID +G + + D E+ ++ Sbjct: 1953 TVIYTATGTDADGTATNNTLRYSLSGDDADK--LIIDATTGEVTLKASADYETQTSYSFN 2010 Query: 657 AVAIDGG-----TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711 VA D G + S+T V + + D+ND+ PV S T + EN+ T I A Sbjct: 2011 VVATDNGAGNFNSGSLSTTQAVIVSVNDLNDNTPVMTSGA-TGSVDENADTSTVIYTATA 2069 Query: 712 HDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770 D D N+ + YS+ GDD++ ++ G E+ DYE+ + Y + A Sbjct: 2070 TDADGTAANSTLVYSL-SGDDADKLIIDATTG----EVTLKASADYET-QTSYSFNVVAT 2123 Query: 771 --------SPPLWNDVRVEILVTDVNDNAPVMKDFQI-IFNNYKDCFPVGPFGRVPAYDA 821 S L V + V D+NDN PVM N D V D Sbjct: 2124 DNGAGNFNSGSLSTTQAVIVSVNDLNDNTPVMTSGATGSVNENADTSTVIYTATATDADG 2183 Query: 822 DVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + LSG++A+ ++++ TTG +TL + + V TD Sbjct: 2184 TAANSTLVYSLSGDDADKLIIDATTGEVTLKASADYETQTSYSFNVVATD 2233 Score = 202 bits (493), Expect = 1e-49 Identities = 192/639 (30%), Positives = 285/639 (44%), Gaps = 73/639 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTADT 69 ++V D ND++PV SV E A + T + T TD D N + Y+ Sbjct: 2361 VSVNDLNDNTPVMTSGA-TGSVDENADTSTVIYTATGTDADGTAANNTLRYS-------- 2411 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV--S 127 L+ +DA D ID +G + +AS D E + Y+ V ATD + S Sbjct: 2412 LSGDDA------------DKLIIDATTGEVTLKASADYETKSSYSFNVIATDNGAGNLNS 2459 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSA 186 LS+T + V++ D NDN P + T SV+E+ + VI ATDAD N+ Sbjct: 2460 GSLSTTQAVTVSVNDLNDNTPVMTSSA-TGSVNENADTST--VIYTATATDADGTATNNT 2516 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG-----SPSRSNTT 241 +RY++ G + + I++++G V+L + DYE SY + A D G S S S T Sbjct: 2517 LRYSLSGDDAAL-LDINAVTGVVTLKASADYETKSSYSFNVIATDNGAGNLNSGSLSTTQ 2575 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 + +++ D+NDNAP TS S+ EN + A DAD G +A T + + Sbjct: 2576 AVTVSVNDLNDNAP-VITSGATASIDENAATSTVVYTATATDAD-GTSANNTISFS---L 2630 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 TG +D +G V D ET++ Y V ATD G + T Sbjct: 2631 TGTDAAAFDVDSSTGVVTLKASADYETKSSYSFNVIATDNGAGNLTDTQAVIVSVNDLND 2690 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQN 418 G + E+ T V T TATDAD +N + + +TG + F I S Sbjct: 2691 NAPVITSGA-TASIDENAATSTVVYTATATDADGTSANNAISFSLTGTDAAA-FDIDSST 2748 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATD-------SGGRSDTAMVQINITDANNYAPVFEN 471 G ++T+ D++ + Y V ATD SG S T V +++ D N+ PV + Sbjct: 2749 G--VVTLKASADYETKASYSFNVVATDNGAGNFNSGSLSTTQAVIVSVNDLNDNTPVMTS 2806 Query: 472 APYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 T SV E+A T + +ATD+D N+ + YSLS + +++ +I+ T Sbjct: 2807 GA-TGSVNENADTSTVIYTATATDADGTAANSTLVYSLSGDDADK--------LIIDATT 2857 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVP-----SLSDTTDVEISVVDVNDNEPVFKQQL 585 G +T D ET + Y V A D G SLS T V +SV D+NDN P Sbjct: 2858 GEVTLKASADYETQTSYSFNVVATDNGAGNFNSGSLSTTQAVIVSVNDLNDNTPTVSAGA 2917 Query: 586 YTANIME-----DALVGTSVSQVGATDADVGLNGRIHYE 619 TA ++E +A GT+ S + T DV G + Y+ Sbjct: 2918 ETAILVEAGGVNNAAAGTNSSSITLTKGDVDTVGSVSYD 2956 Score = 101 bits (242), Expect = 3e-19 Identities = 97/316 (30%), Positives = 143/316 (45%), Gaps = 42/316 (13%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 ++V D ND++PV AS+ E A++ T V T ATD D G +A + L D Sbjct: 2683 VSVNDLNDNAPVITSGA-TASIDENAATSTVVYTATATDAD-GTSANNAISFSLTGTDAA 2740 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV--SD 128 F ID +G + +AS D E A Y+ V ATD + S Sbjct: 2741 ------------------AFDIDSSTGVVTLKASADYETKASYSFNVVATDNGAGNFNSG 2782 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-VGANSAI 187 LS+T + V++ D NDN P + T SV+E+ + VI ATDAD ANS + Sbjct: 2783 SLSTTQAVIVSVNDLNDNTPVMTSGA-TGSVNENADTST--VIYTATATDADGTAANSTL 2839 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG-----SPSRSNTTQ 242 Y++ G + + ID+ +G+V+L + DYE SY + A D G S S S T Sbjct: 2840 VYSLSGDDAD-KLIIDATTGEVTLKASADYETQTSYSFNVVATDNGAGNFNSGSLSTTQA 2898 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE-LTYTMTDKDY 301 +++++ D+NDN P +VS + +A G N+ +T T D D Sbjct: 2899 VIVSVNDLNDNTP---------TVSAGAETAILVEAGGVNNAAAGTNSSSITLTKGDVDT 2949 Query: 302 TGNVDLPITIDPRSGW 317 G+V T +GW Sbjct: 2950 VGSVSYDATYLTNNGW 2965 >UniRef50_UPI0000D5573F Cluster: PREDICTED: similar to CG3389-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG3389-PA - Tribolium castaneum Length = 1870 Score = 260 bits (636), Expect = 5e-67 Identities = 218/750 (29%), Positives = 341/750 (45%), Gaps = 54/750 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + +LD N+ +PVF + ++RE + G+ + LKA D D K A++ YTI + Sbjct: 826 VTILDINNKNPVF-YEPGSVTMRENTAVGSVIAKLKAKDLD--KTAQLVYTINPKFCEAK 882 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N + + F + SG L LDRE V + + + D AS ++ Sbjct: 883 N--ERGILLKLSDFNCAETFHLHPMSGVLTIAQQLDREMVEKVQMGLMVEDTASETGPQI 940 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+T TI +NI D NDN P+F + Y S+ E+ + I + A DAD N I Y Sbjct: 941 STT-TITINIEDINDNSPKFRQPYYKFSITENSK--NGVTIGNVLAEDAD--KNKTITYT 995 Query: 191 IIGGN--TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 + G T++ + +DS SGD+ + +D+E L I+A D G P+R + ++ I I Sbjct: 996 LDGRFEITELIY-LDSNSGDLVVANKIDHEIYDWLNLTIKATDSGIPARFSRVEIFIQIL 1054 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D NDN P F +SE+ P+G + ++A DAD G ++TY + G Sbjct: 1055 DENDNNPFFLGEPQSLLISEDTPVGRQVAIIEAKDADSGEFGKITYLLDRISSEGK---- 1110 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG------GDPPRSATATXXXXXXXXXXX 362 +ID SG + S +LDRE + Y L++ A D R+A Sbjct: 1111 FSIDADSGILKVSDKLDREEKHSYLLVIEAWDNYQYGFNSGESRNAFKHINVTILDVNDN 1170 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN----RLHYEITGGNTRGRFSITSQN 418 Y V + E PG + T A+DAD+ N ++ +I+ GN + F++ SQ Sbjct: 1171 HPQLHVPPYCVNITEFHEPGQAITTFHASDADDPNTSNGQVIIDISDGNQKNFFAL-SQI 1229 Query: 419 GRGLITVAQPLDFK-QERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPY- 474 + + + Y L + A D G S + I +TD N++ P F P+ Sbjct: 1230 SEWSAELRTTTSLRGRHGNYTLIIRAQDLGTPSHLIEEPLHICVTDFNDHPPTFVTPPHN 1289 Query: 475 -TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 T V E+A IG+ ++ + ATD DVG N + Y L ++ A H + F + P +G + Sbjct: 1290 STLRVPENATIGSALVKIIATDEDVGSNGIVRYRLKAD-----PAGHWKSFNLQPVSGIL 1344 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593 LDR+ Y + + A D GVPSLS D+ + V ++ND +P F +T N E+ Sbjct: 1345 ELRLPLDRKKQKVYDIRIEAYDLGVPSLSSDLDLTVYVSNINDYQPQFMGDEFTVNFTEN 1404 Query: 594 ALVGTSVSQVGAT-DADV----GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648 ++ T D D G I Y + E G F + P ++ ++ LDRE Sbjct: 1405 KPSEVERQKLPQTVDRDELEFDGPFAPICYFI-VGGNENGLFKLHPVEHILTVSRPLDRE 1463 Query: 649 SVATHDLKAVAIDGGT-PPQSSTVI---------VHIKIEDINDSPPVFESDCLTFYISE 698 TH L A + T PP++ + V +K+ D+ND+ P F T +S Sbjct: 1464 EKDTHLLLVKATEDCTKPPRNESFFDSSDDTQLKVIVKVLDVNDNAPQFIHRVFTGGVST 1523 Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 + GTT E++A D D NA + Y + G Sbjct: 1524 ATSFGTTFMEVKAEDADLDDNARMSYFLIG 1553 Score = 253 bits (619), Expect = 6e-65 Identities = 246/869 (28%), Positives = 385/869 (44%), Gaps = 92/869 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTADT 69 I V D NDH+P+FE Y SV E S GT++L ++A D D N + Y I+ +D Sbjct: 713 IYVQDVNDHAPLFEYTFYNKSVPEDISGGTSILQVRAKDFDGSSPNNRIVYRIQNGASDK 772 Query: 70 --LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 + PE I GA L L + + Y++ V A D A P Sbjct: 773 FIIAPESGI---------------ISVARGASLD-PDLTQPRTLHYSLNVVALDGA-PGE 815 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN--- 184 ++L + T++V I+D N+ P F E +V++ E+ +V VIAK+KA D D A Sbjct: 816 NQLQAGVTVNVTILDINNKNPVFYEPG-SVTMRENTAV--GSVIAKLKAKDLDKTAQLVY 872 Query: 185 ------------SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232 I + N F + +SG +++ + LD E V ++ + +D Sbjct: 873 TINPKFCEAKNERGILLKLSDFNCAETFHLHPMSGVLTIAQQLDREMVEKVQMGLMVEDT 932 Query: 233 GSPS--RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290 S + + +TT + INI D+NDN+P+F ++ S++EN G +I V A DAD+ N Sbjct: 933 ASETGPQISTTTITINIEDINDNSPKFRQPYYKFSITENSKNGVTIGNVLAEDADK--NK 990 Query: 291 ELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350 +TYT+ D + I +D SG + + ++D E L + ATD G P R + Sbjct: 991 TITYTL---DGRFEITELIYLDSNSGDLVVANKIDHEIYDWLNLTIKATDSGIPARFSRV 1047 Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNT 408 F+ + ++ED P G V + A DAD E ++ Y + ++ Sbjct: 1048 EIFIQILDENDNNPFFLGEPQSLLISEDTPVGRQVAIIEAKDADSGEFGKITYLLDRISS 1107 Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS------GGRSDTAMVQINIT-- 460 G+FSI + +G ++ V+ LD +++ Y+L + A D+ G S A IN+T Sbjct: 1108 EGKFSIDADSG--ILKVSDKLDREEKHSYLLVIEAWDNYQYGFNSGESRNAFKHINVTIL 1165 Query: 461 DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG--INAQITYSLSSEISNEAVA 518 D N+ P PY ++ E G + A+D+D N Q+ +S A Sbjct: 1166 DVNDNHPQLHVPPYCVNITEFHEPGQAITTFHASDADDPNTSNGQVIIDISDGNQKNFFA 1225 Query: 519 HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578 I+ + + T L R Y L + A+D G PS + I V D ND+ Sbjct: 1226 LSQ----ISEWSAELRTTTSL-RGRHGNYTLIIRAQDLGTPSHLIEEPLHICVTDFNDHP 1280 Query: 579 PVFKQQLY--TANIMEDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDREEGSFVIDP 634 P F + T + E+A +G+++ ++ ATD DVG NG + Y L DP + SF + P Sbjct: 1281 PTFVTPPHNSTLRVPENATIGSALVKIIATDEDVGSNGIVRYRLKADPAGHWK-SFNLQP 1339 Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694 SG++ LDR+ +D++ A D G P SS + + + + +IND P F D T Sbjct: 1340 VSGILELRLPLDRKKQKVYDIRIEAYDLGVPSLSSDLDLTVYVSNINDYQPQFMGDEFTV 1399 Query: 695 YISENSPIGTTIGEI-RAHDPDE----GPNAVVHYSIKGGDDSNSFSLE----------- 738 +EN P ++ + D DE GP A + Y I GG+++ F L Sbjct: 1400 NFTENKPSEVERQKLPQTVDRDELEFDGPFAPICYFIVGGNENGLFKLHPVEHILTVSRP 1459 Query: 739 -TRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDF 797 R+ D L+ D P + + L +V + V DVNDNAP Sbjct: 1460 LDREEKDTHLLLVKATEDCTKPPRNESFFDSSDDTQL----KVIVKVLDVNDNAPQF-IH 1514 Query: 798 QIIFNNYKDCFPVG-PFGRVPAYDADVTD 825 ++ G F V A DAD+ D Sbjct: 1515 RVFTGGVSTATSFGTTFMEVKAEDADLDD 1543 Score = 235 bits (576), Expect = 1e-59 Identities = 227/793 (28%), Positives = 355/793 (44%), Gaps = 63/793 (7%) Query: 88 DVFRIDGRSGA---LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDN 144 DV R++ S + LDRE Y +++ TD + ++ + + V D N Sbjct: 96 DVIRVENISPTEADVYLNKELDRETRDEYPLVLTLTDGRLGHGNYVTQSLLLLVE--DVN 153 Query: 145 DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ-FSID 203 DN P F+ ++++ ED + VIA ++ATD D GA + Y + +T+ FS+ Sbjct: 154 DNTPIFTSHQSSITLREDAAPG---VIATLEATDLDEGAYGQVVYQLQEVDTKESLFSVS 210 Query: 204 SLSGD--VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT--TQLLINIRDVNDNAPRFYT 259 + G V LV +LDYE+ ++L + A D R NT LL+ + DV D P F Sbjct: 211 TAGGKAIVRLVGSLDYEKQTLHQLKVLAVDRAKQGRVNTGTAALLVKVEDVEDQPPEFVR 270 Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319 ++EN PIG S+++V A D D GVN + Y+++ D+ +++ +G + Sbjct: 271 VTSVARIAENAPIGTSVLQVTAIDGDRGVNNPILYSLSSNSIDRITDV-FSLEETTGTLL 329 Query: 320 TSGQLDRE----TQAKYQLLVTATDGG---DPPRSATATXXXXXXXXXXXXXXFMPGQYE 372 T+ LDRE + Y L +TAT+ G PP S T F G YE Sbjct: 330 TAKTLDRESLSLSSGTYILQITATEYGGKIKPPPSVTTEVTVIITDINDETPKFRSGYYE 389 Query: 373 VELAEDEPPGTPVVTLTAT-----DADEDNRLHYEITGGNTRGRFSITS----QNGRGLI 423 E+AE+ P TP+ L + D D+ +++ F IT +I Sbjct: 390 CEIAENAPVNTPLTFLGSAMPEVYDHDQGINGTFQLYVKGASDVFEITPTKAINEATFMI 449 Query: 424 TVAQP--LDFKQERRYVLTVSATD---SGGRSDTAMVQINITDANNYAPVFENAPYTASV 478 V LD+++ + T+ A + + + V +I D N+ P F Y V Sbjct: 450 RVKNSTFLDYEKIKTINFTLVAKEIVKHNPKFNEVPVVAHILDRNDNYPEFTKNVYEVFV 509 Query: 479 FEDAPIGTTVLVVSATDSDVGI--NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 E+ IG TV V A D D G+ I Y+ S + H +I+ +T Sbjct: 510 PENCDIGATVAWVQALDDDSGVFGTMGIRYTHLSGSIQHMLNLHPTTGIISVKTAG---G 566 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 DRE +S + LTV ARD T + I++ DVNDN P+F Q Y A ++E+ L Sbjct: 567 PNWDREQISRHYLTVEARDDLGQGNRITVQLIINIEDVNDNPPIFTQNRYEARLLENKLD 626 Query: 597 GTSVSQVGATDADVG--LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD-------- 646 + +V A DAD+ N I Y L D +F I+P++G+I+ ++D Sbjct: 627 FENPLKVEARDADLNGTKNNEIEYSLF-GDLSH-NFTIEPSTGIIKPRTSIDFEALEGSL 684 Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706 ++S+ L A D GTP S V ++I ++D+ND P+FE + E+ GT+I Sbjct: 685 KDSIRQLHLTVRARDWGTPSLFSDVPLYIYVQDVNDHAPLFEYTFYNKSVPEDISGGTSI 744 Query: 707 GEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYE 764 ++RA D D PN + Y I+ G S+ F + G +D D PR Y Sbjct: 745 LQVRAKDFDGSSPNNRIVYRIQNG-ASDKFIIAPESGIISVARGASLDPDLTQPRTLHYS 803 Query: 765 L-VIRAASPP----LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPA 818 L V+ P L V V + + D+N+ PV + + ++ VG ++ A Sbjct: 804 LNVVALDGAPGENQLQAGVTVNVTILDINNKNPVFYEPGSV--TMRENTAVGSVIAKLKA 861 Query: 819 YDADVTDKLQYRI 831 D D T +L Y I Sbjct: 862 KDLDKTAQLVYTI 874 Score = 223 bits (545), Expect = 6e-56 Identities = 230/834 (27%), Positives = 372/834 (44%), Gaps = 88/834 (10%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAE-VEYTIELVTADTLN 71 + D ND +P F YE + E A T + L + ++ + + + T +L + Sbjct: 373 ITDINDETPKFRSGYYECEIAENAPVNTPLTFLGSAMPEVYDHDQGINGTFQLYVKGASD 432 Query: 72 PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131 + + F I ++ L ++ K +T++ K + +P + + Sbjct: 433 VFEITPTKAIN----EATFMIRVKNSTFL---DYEKIKTINFTLVAKEIVKHNPKFNEVP 485 Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA--NSAIRY 189 A +I+D NDNYP+F++ Y V V E+ + +A ++A D D G IRY Sbjct: 486 VVA----HILDRNDNYPEFTKNVYEVFVPENCDI--GATVAWVQALDDDSGVFGTMGIRY 539 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTL-----DYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 + G+ Q ++ +G +S VKT D EQ+ + L + A+D T QL+ Sbjct: 540 THLSGSIQHMLNLHPTTGIIS-VKTAGGPNWDREQISRHYLTVEARDDLGQGNRITVQLI 598 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGV-NAELTYTMTDKDYT 302 INI DVNDN P F + ++ + EN + ++V+A DAD G N E+ Y++ Sbjct: 599 INIEDVNDNPPIFTQNRYEARLLENKLDFENPLKVEARDADLNGTKNNEIEYSLF----- 653 Query: 303 GNVDLPITIDPRSGWVYTSGQLD--------RETQAKYQLLVTATDGGDPPRSATATXXX 354 G++ TI+P +G + +D +++ + L V A D G P + Sbjct: 654 GDLSHNFTIEPSTGIIKPRTSIDFEALEGSLKDSIRQLHLTVRARDWGTPSLFSDVPLYI 713 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGR 411 F Y + ED GT ++ + A D D +NR+ Y I G + + Sbjct: 714 YVQDVNDHAPLFEYTFYNKSVPEDISGGTSILQVRAKDFDGSSPNNRIVYRIQNGAS-DK 772 Query: 412 FSITSQNGRGLITVAQPL----DFKQER--RYVLTVSATDS--GGRSDTAMVQINIT--D 461 F I ++G +I+VA+ D Q R Y L V A D G A V +N+T D Sbjct: 773 FIIAPESG--IISVARGASLDPDLTQPRTLHYSLNVVALDGAPGENQLQAGVTVNVTILD 830 Query: 462 ANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS---EISNEA-- 516 NN PVF P + ++ E+ +G+ + + A D D AQ+ Y+++ E NE Sbjct: 831 INNKNPVFYE-PGSVTMRENTAVGSVIAKLKAKDLDK--TAQLVYTINPKFCEAKNERGI 887 Query: 517 -VAHHD----QQFVINPQTGAITTNKLLDRETMS----GYLLTVTARDGGVPSLSDTTDV 567 + D + F ++P +G +T + LDRE + G ++ TA + G P +S TT + Sbjct: 888 LLKLSDFNCAETFHLHPMSGVLTIAQQLDREMVEKVQMGLMVEDTASETG-PQISTTT-I 945 Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627 I++ D+NDN P F+Q Y +I E++ G ++ V A DAD N I Y LD + Sbjct: 946 TINIEDINDNSPKFRQPYYKFSITENSKNGVTIGNVLAEDADK--NKTITYTLDGRFEIT 1003 Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687 +D SG + +D E +L A D G P + S V + I+I D ND+ P F Sbjct: 1004 ELIYLDSNSGDLVVANKIDHEIYDWLNLTIKATDSGIPARFSRVEIFIQILDENDNNPFF 1063 Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747 + + ISE++P+G + I A D D G + Y + FS++ +D Sbjct: 1064 LGEPQSLLISEDTPVGRQVAIIEAKDADSGEFGKITYLLDRISSEGKFSID----ADSGI 1119 Query: 748 LVTMVDLDYESPRKKYELVIRA--------ASPPLWNDVR-VEILVTDVNDNAP 792 L LD E + Y LVI A S N + + + + DVNDN P Sbjct: 1120 LKVSDKLDREE-KHSYLLVIEAWDNYQYGFNSGESRNAFKHINVTILDVNDNHP 1172 Score = 220 bits (538), Expect = 4e-55 Identities = 248/944 (26%), Positives = 409/944 (43%), Gaps = 103/944 (10%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72 V D ND++P+F Q ++RE A+ G + TL+ATD D G +V Y ++ V DT Sbjct: 149 VEDVNDNTPIFTSHQSSITLREDAAPG-VIATLEATDLDEGAYGQVVYQLQEV--DT--- 202 Query: 73 EDAXXXXXXXXXXVQDVFRIDGRSGALLTR--ASLDREKVARYTVLVKATDQASPVSDRL 130 + +F + G + R SLD EK + + V A D+A R+ Sbjct: 203 -------------KESLFSVSTAGGKAIVRLVGSLDYEKQTLHQLKVLAVDRAK--QGRV 247 Query: 131 SS-TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 ++ TA + V + D D P+F T + E+ + + + ++ A D D G N+ I Y Sbjct: 248 NTGTAALLVKVEDVEDQPPEFVRVTSVARIAENAPIGTS--VLQVTAIDGDRGVNNPILY 305 Query: 190 AIIGGNTQM---QFSIDSLSGDVSLVKTLDYEQVR----SYRLVIRAQDGG---SPSRSN 239 ++ + FS++ +G + KTLD E + +Y L I A + G P S Sbjct: 306 SLSSNSIDRITDVFSLEETTGTLLTAKTLDRESLSLSSGTYILQITATEYGGKIKPPPSV 365 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRV-----QAYDADEGVNAELTY 294 TT++ + I D+ND P+F + ++ ++EN P+ + + + YD D+G+N Sbjct: 366 TTEVTVIITDINDETPKFRSGYYECEIAENAPVNTPLTFLGSAMPEVYDHDQGINGTFQL 425 Query: 295 TMTDKDYTGNVDLPITIDPRSGW--VYTSGQLDRETQAKYQLLVTATD-GGDPPRSATAT 351 + + I+ + V S LD E + A + P+ Sbjct: 426 YVKGASDVFEITPTKAINEATFMIRVKNSTFLDYEKIKTINFTLVAKEIVKHNPKFNEVP 485 Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE----DNRLHYEITGGN 407 F YEV + E+ G V + A D D + Y G+ Sbjct: 486 VVAHILDRNDNYPEFTKNVYEVFVPENCDIGATVAWVQALDDDSGVFGTMGIRYTHLSGS 545 Query: 408 TRGRFSITSQNG-RGLITVAQP-LDFKQERRYVLTVSATDSGGRSDTAMVQ--INITDAN 463 + ++ G + T P D +Q R+ LTV A D G+ + VQ INI D N Sbjct: 546 IQHMLNLHPTTGIISVKTAGGPNWDREQISRHYLTVEARDDLGQGNRITVQLIINIEDVN 605 Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG--INAQITYSLSSEISNEAVAHHD 521 + P+F Y A + E+ L V A D+D+ N +I YSL ++S+ Sbjct: 606 DNPPIFTQNRYEARLLENKLDFENPLKVEARDADLNGTKNNEIEYSLFGDLSH------- 658 Query: 522 QQFVINPQTGAITTNKLLDRETMSGYL--------LTVTARDGGVPSLSDTTDVEISVVD 573 F I P TG I +D E + G L LTV ARD G PSL + I V D Sbjct: 659 -NFTIEPSTGIIKPRTSIDFEALEGSLKDSIRQLHLTVRARDWGTPSLFSDVPLYIYVQD 717 Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVI 632 VND+ P+F+ Y ++ ED GTS+ QV A D D N RI Y + ++ F+I Sbjct: 718 VNDHAPLFEYTFYNKSVPEDISGGTSILQVRAKDFDGSSPNNRIVYRI--QNGASDKFII 775 Query: 633 DPASGVIRTNKA------LDRESVATHDLKAVAIDG--GTPPQSSTVIVHIKIEDINDSP 684 P SG+I + L + + L VA+DG G + V V++ I DIN+ Sbjct: 776 APESGIISVARGASLDPDLTQPRTLHYSLNVVALDGAPGENQLQAGVTVNVTILDINNKN 835 Query: 685 PVF-ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL------ 737 PVF E +T + EN+ +G+ I +++A D D+ V + K + N + Sbjct: 836 PVFYEPGSVT--MRENTAVGSVIAKLKAKDLDKTAQLVYTINPKFCEAKNERGILLKLSD 893 Query: 738 ----ETRQGSDKAELVTMV-DLDYESPRK-KYELVIR---AASPPLWNDVRVEILVTDVN 788 ET + ++T+ LD E K + L++ + + P + + I + D+N Sbjct: 894 FNCAETFHLHPMSGVLTIAQQLDREMVEKVQMGLMVEDTASETGPQISTTTITINIEDIN 953 Query: 789 DNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSG--NNANLILLNETT 846 DN+P + F+ ++ G V A DAD + Y L G LI L+ + Sbjct: 954 DNSPKFRQPYYKFSITENSKNGVTIGNVLAEDADKNKTITY-TLDGRFEITELIYLDSNS 1012 Query: 847 GSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITE 889 G + ++ +++ + + + TD G+ + +++ ++++ E Sbjct: 1013 GDLVVANKIDHEIYDWLNLTIKATDSGIPARFSRVEIFIQILDE 1056 Score = 220 bits (538), Expect = 4e-55 Identities = 228/839 (27%), Positives = 366/839 (43%), Gaps = 90/839 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D D P F A + E A GT+VL + A D D G N + Y++ + D + Sbjct: 256 VKVEDVEDQPPEFVRVTSVARIAENAPIGTSVLQVTAIDGDRGVNNPILYSLSSNSIDRI 315 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA----RYTVLVKATDQASPV 126 DVF ++ +G LLT +LDRE ++ Y + + AT+ + Sbjct: 316 T----------------DVFSLEETTGTLLTAKTLDRESLSLSSGTYILQITATEYGGKI 359 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVI----AKIKATDADVG 182 S T + V I D ND P+F Y + E+ V + P+ A + D D G Sbjct: 360 KPPPSVTTEVTVIITDINDETPKFRSGYYECEIAENAPV-NTPLTFLGSAMPEVYDHDQG 418 Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSL---VKT---LDYEQVRSYRLVIRAQDGGSPS 236 N + + G + + + + + VK LDYE++++ + A++ + Sbjct: 419 INGTFQLYVKGASDVFEITPTKAINEATFMIRVKNSTFLDYEKIKTINFTLVAKEIVKHN 478 Query: 237 -RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295 + N ++ +I D NDN P F ++++ V EN IG ++ VQA D D GV + Sbjct: 479 PKFNEVPVVAHILDRNDNYPEFTKNVYEVFVPENCDIGATVAWVQALDDDSGVFGTMGIR 538 Query: 296 MTDKDYTGNVDLPITIDPRSG--WVYTSG--QLDRETQAKYQLLVTATDGGDPPRSATAT 351 T +G++ + + P +G V T+G DRE +++ L V A D T Sbjct: 539 YT--HLSGSIQHMLNLHPTTGIISVKTAGGPNWDREQISRHYLTVEARDDLGQGNRITVQ 596 Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD----EDNRLHYEITGGN 407 F +YE L E++ + + A DAD ++N + Y + G Sbjct: 597 LIINIEDVNDNPPIFTQNRYEARLLENKLDFENPLKVEARDADLNGTKNNEIEYSLFGDL 656 Query: 408 TRGRFSITSQNGRGLITVAQPLDFK--------QERRYVLTVSATDSGGRS--DTAMVQI 457 + + T + G+I +DF+ R+ LTV A D G S + I Sbjct: 657 SH---NFTIEPSTGIIKPRTSIDFEALEGSLKDSIRQLHLTVRARDWGTPSLFSDVPLYI 713 Query: 458 NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEA 516 + D N++AP+FE Y SV ED GT++L V A D D N +I Y + + S++ Sbjct: 714 YVQDVNDHAPLFEYTFYNKSVPEDISGGTSILQVRAKDFDGSSPNNRIVYRIQNGASDKF 773 Query: 517 VAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG--GVPSLSDTTDVEISVVDV 574 + + +I+ GA L T+ Y L V A DG G L V ++++D+ Sbjct: 774 II-APESGIISVARGASLDPDLTQPRTLH-YSLNVVALDGAPGENQLQAGVTVNVTILDI 831 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK----DREEG-- 628 N+ PVF + + + E+ VG+ ++++ A D D ++ Y ++PK E G Sbjct: 832 NNKNPVFYEP-GSVTMRENTAVGSVIAKLKAKDLD--KTAQLVYTINPKFCEAKNERGIL 888 Query: 629 ----------SFVIDPASGVIRTNKALDRESVATHDLKAVAID--GGTPPQSSTVIVHIK 676 +F + P SGV+ + LDRE V + + D T PQ ST + I Sbjct: 889 LKLSDFNCAETFHLHPMSGVLTIAQQLDREMVEKVQMGLMVEDTASETGPQISTTTITIN 948 Query: 677 IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736 IEDIND+ P F F I+ENS G TIG + A D D+ N + Y++ G + Sbjct: 949 IEDINDNSPKFRQPYYKFSITENSKNGVTIGNVLAEDADK--NKTITYTLDGRFEITEL- 1005 Query: 737 LETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAP 792 S+ +LV +D+E L I+A P ++ V + I + D NDN P Sbjct: 1006 --IYLDSNSGDLVVANKIDHEI-YDWLNLTIKATDSGIPARFSRVEIFIQILDENDNNP 1061 Score = 185 bits (450), Expect = 2e-44 Identities = 159/556 (28%), Positives = 258/556 (46%), Gaps = 39/556 (7%) Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 + P+G I +++ D D L++ + + + + + I P VY + +LDRE Sbjct: 64 KETPVGTLIYKLRGTDPD---GDPLSFGVRSQSGSDVIRVE-NISPTEADVYLNKELDRE 119 Query: 328 TQAKYQLLVTATDGG-DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386 T+ +Y L++T TDG T + F Q + L ED PG + Sbjct: 120 TRDEYPLVLTLTDGRLGHGNYVTQSLLLLVEDVNDNTPIFTSHQSSITLREDAAPGV-IA 178 Query: 387 TLTATDADED--NRLHYEITGGNTR-GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443 TL ATD DE ++ Y++ +T+ FS+++ G+ ++ + LD++++ + L V A Sbjct: 179 TLEATDLDEGAYGQVVYQLQEVDTKESLFSVSTAGGKAIVRLVGSLDYEKQTLHQLKVLA 238 Query: 444 TDSG--GR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499 D GR + TA + + + D + P F A + E+APIGT+VL V+A D D G Sbjct: 239 VDRAKQGRVNTGTAALLVKVEDVEDQPPEFVRVTSVARIAENAPIGTSVLQVTAIDGDRG 298 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS----GYLLTVTARD 555 +N I YSLSS ++ F + TG + T K LDRE++S Y+L +TA + Sbjct: 299 VNNPILYSLSS----NSIDRITDVFSLEETTGTLLTAKTLDRESLSLSSGTYILQITATE 354 Query: 556 GG---VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT-----D 607 G P S TT+V + + D+ND P F+ Y I E+A V T ++ +G+ D Sbjct: 355 YGGKIKPPPSVTTEVTVIITDINDETPKFRSGYYECEIAENAPVNTPLTFLGSAMPEVYD 414 Query: 608 ADVGLNGRIH-YELDPKDREE--GSFVIDPASGVIRTNKA--LDRESVATHDLKAVAID- 661 D G+NG Y D E + I+ A+ +IR + LD E + T + VA + Sbjct: 415 HDQGINGTFQLYVKGASDVFEITPTKAINEATFMIRVKNSTFLDYEKIKTINFTLVAKEI 474 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 P+ + V V I D ND+ P F + ++ EN IG T+ ++A D D G Sbjct: 475 VKHNPKFNEVPVVAHILDRNDNYPEFTKNVYEVFVPENCDIGATVAWVQALDDDSGVFGT 534 Query: 722 --VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR 779 + Y+ G + +L G + + D E + Y V N + Sbjct: 535 MGIRYTHLSGSIQHMLNLHPTTGIISVKTAGGPNWDREQISRHYLTVEARDDLGQGNRIT 594 Query: 780 VEILVT--DVNDNAPV 793 V++++ DVNDN P+ Sbjct: 595 VQLIINIEDVNDNPPI 610 Score = 177 bits (431), Expect = 4e-42 Identities = 205/771 (26%), Positives = 334/771 (43%), Gaps = 65/771 (8%) Query: 170 VIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA 229 +I K++ TD D S + G + +I DV L K LD E Y LV+ Sbjct: 71 LIYKLRGTDPDGDPLSFGVRSQSGSDVIRVENISPTEADVYLNKELDRETRDEYPLVLTL 130 Query: 230 QDGGSPSRSNTTQ-LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV 288 DG + TQ LL+ + DVNDN P F + ++ E+ G I ++A D DEG Sbjct: 131 TDGRLGHGNYVTQSLLLLVEDVNDNTPIFTSHQSSITLREDAAPGV-IATLEATDLDEGA 189 Query: 289 NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348 ++ Y + + D ++ ++ V G LD E Q +QL V A D R Sbjct: 190 YGQVVYQLQEVDTKESL-FSVSTAGGKAIVRLVGSLDYEKQTLHQLKVLAVDRAKQGRVN 248 Query: 349 TATXXXXXXXXXXXXX--XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEIT 404 T T F+ +AE+ P GT V+ +TA D D +N + Y ++ Sbjct: 249 TGTAALLVKVEDVEDQPPEFVRVTSVARIAENAPIGTSVLQVTAIDGDRGVNNPILYSLS 308 Query: 405 GGNTRGRFSITS-QNGRGLITVAQPLDFKQ----ERRYVLTVSATDSGGR-----SDTAM 454 + + S + G + A+ LD + Y+L ++AT+ GG+ S T Sbjct: 309 SNSIDRITDVFSLEETTGTLLTAKTLDRESLSLSSGTYILQITATEYGGKIKPPPSVTTE 368 Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT-----DSDVGINAQITYSLS 509 V + ITD N+ P F + Y + E+AP+ T + + + D D GIN T+ L Sbjct: 369 VTVIITDINDETPKFRSGYYECEIAENAPVNTPLTFLGSAMPEVYDHDQGING--TFQLY 426 Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNK--LLDRETMSGYLLTVTARD--GGVPSLSDTT 565 + +++ V IN T I LD E + T+ A++ P ++ Sbjct: 427 VKGASD-VFEITPTKAINEATFMIRVKNSTFLDYEKIKTINFTLVAKEIVKHNPKFNEVP 485 Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625 V ++D NDN P F + +Y + E+ +G +V+ V A D D G+ G + Sbjct: 486 -VVAHILDRNDNYPEFTKNVYEVFVPENCDIGATVAWVQALDDDSGVFGTMGIRYTHLSG 544 Query: 626 E-EGSFVIDPASGVIRTNKA----LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680 + + P +G+I A DRE ++ H L A D TV + I IED+ Sbjct: 545 SIQHMLNLHPTTGIISVKTAGGPNWDREQISRHYLTVEARDDLGQGNRITVQLIINIEDV 604 Query: 681 NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG--PNAVVHYSIKGGDDSNSFSLE 738 ND+PP+F + + EN ++ A D D N + YS+ G D S++F++E Sbjct: 605 NDNPPIFTQNRYEARLLENKLDFENPLKVEARDADLNGTKNNEIEYSLFG-DLSHNFTIE 663 Query: 739 TRQGSDKAELVTMVDLD-----YESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDN 790 G K T +D + + ++ L +RA +P L++DV + I V DVND+ Sbjct: 664 PSTGIIKPR--TSIDFEALEGSLKDSIRQLHLTVRARDWGTPSLFSDVPLYIYVQDVNDH 721 Query: 791 APVMKDFQIIFNNY---KDCFPVGPFGRVPAYDAD---VTDKLQYRILSGNNANLILLNE 844 AP+ F+ F N +D +V A D D +++ YRI +G + I+ E Sbjct: 722 APL---FEYTFYNKSVPEDISGGTSILQVRAKDFDGSSPNNRIVYRIQNGASDKFIIAPE 778 Query: 845 T-----TGSMTLSPQLNTNVPKLATMEVSVTDGV---NEIKAMMQLSVRLI 887 + +L P L ++ V DG N+++A + ++V ++ Sbjct: 779 SGIISVARGASLDPDLTQPRTLHYSLNVVALDGAPGENQLQAGVTVNVTIL 829 Score = 172 bits (419), Expect = 1e-40 Identities = 183/704 (25%), Positives = 299/704 (42%), Gaps = 73/704 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 IN+ D ND+SP F Y+ S+ E + +G T+ + A D D KN + YT++ Sbjct: 947 INIEDINDNSPKFRQPYYKFSITENSKNGVTIGNVLAEDAD--KNKTITYTLD------- 997 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + ++ +D SG L+ +D E + +KATD P Sbjct: 998 -----------GRFEITELIYLDSNSGDLVVANKIDHEIYDWLNLTIKATDSGIPAR--- 1043 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S I + I+D+NDN P F + ++ + ED V +A I+A DAD G I Y Sbjct: 1044 FSRVEIFIQILDENDNNPFFLGEPQSLLISEDTPVGRQ--VAIIEAKDADSGEFGKITYL 1101 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG------GSPSRSNTTQLL 244 + +++ +FSID+ SG + + LD E+ SY LVI A D SR+ + Sbjct: 1102 LDRISSEGKFSIDADSGILKVSDKLDREEKHSYLLVIEAWDNYQYGFNSGESRNAFKHIN 1161 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG--VNAELTYTMTDKDYT 302 + I DVNDN P+ + + +++E G +I A DAD+ N ++ ++D + Sbjct: 1162 VTILDVNDNHPQLHVPPYCVNITEFHEPGQAITTFHASDADDPNTSNGQVIIDISDGNQK 1221 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 L I S + T+ L R Y L++ A D G P Sbjct: 1222 NFFALS-QISEWSAELRTTTSL-RGRHGNYTLIIRAQDLGTPSHLIEEPLHICVTDFNDH 1279 Query: 363 XXXFM--PGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQN 418 F+ P + + E+ G+ +V + ATD D + + Y + S Q Sbjct: 1280 PPTFVTPPHNSTLRVPENATIGSALVKIIATDEDVGSNGIVRYRLKADPAGHWKSFNLQP 1339 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTA 476 G++ + PLD K+++ Y + + A D G S + + +++ N+Y P F +T Sbjct: 1340 VSGILELRLPLDRKKQKVYDIRIEAYDLGVPSLSSDLDLTVYVSNINDYQPQFMGDEFTV 1399 Query: 477 SVFEDAPIGTTVLVVSAT-DSDV----GINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 + E+ P + T D D G A I Y + NE + F ++P Sbjct: 1400 NFTENKPSEVERQKLPQTVDRDELEFDGPFAPICYFIVG--GNE-----NGLFKLHPVEH 1452 Query: 532 AITTNKLLDRETMSGYLLTVTA-RDGGVP----SLSDTTD-----VEISVVDVNDNEPVF 581 +T ++ LDRE +LL V A D P S D++D V + V+DVNDN P F Sbjct: 1453 ILTVSRPLDREEKDTHLLLVKATEDCTKPPRNESFFDSSDDTQLKVIVKVLDVNDNAPQF 1512 Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK----------DREEGSFV 631 +++T + GT+ +V A DAD+ N R+ Y L K D + F+ Sbjct: 1513 IHRVFTGGVSTATSFGTTFMEVKAEDADLDDNARMSYFLIGKVQMTLTEGLEDLKRDPFL 1572 Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675 +D +G ++ N D + D G + V +++ Sbjct: 1573 VDRDTGAVQLNFDPQEGMKGYFDFMVLVNDTGGLQDMARVFIYL 1616 >UniRef50_Q967F4 Cluster: Cadherin-related hmr-1 precursor; n=3; Caenorhabditis|Rep: Cadherin-related hmr-1 precursor - Caenorhabditis elegans Length = 2920 Score = 258 bits (633), Expect = 1e-66 Identities = 254/928 (27%), Positives = 404/928 (43%), Gaps = 80/928 (8%) Query: 3 VPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 + FC + V+D ND+SP FE YE SV + GT+V+T+ A D D NAE+ Y++ Sbjct: 960 IGFC-QFSVEVVDINDNSPQFERPSYETSVSRFEAVGTSVITVFAFDNDAAHNAEITYSL 1018 Query: 63 ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122 E+ DT E+ D F + R +T K ++ V A D Sbjct: 1019 EI---DTTAGEEHQNDL--------DFFELVNRRSGEITLIKPIPMKTQKFIFNVIADDN 1067 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT---VSVDEDISVTDNPVIAKIKATDA 179 P + L S+A + +N++D P++ ++VDE++ + N VI + +A + Sbjct: 1068 GIP--EALQSSAQVTLNVLDKQQKAPKWQTSPDCKPGITVDENVEL--NKVILRCRAVSS 1123 Query: 180 DVGANSAIRYAII-----GGNTQMQF-SIDSLSG-----DVSLVKTLDYEQVRSYRLVIR 228 NS + Y + G + +F + +V +++ LDYEQV +Y L + Sbjct: 1124 GDSRNSDVIYKLTASGGPGNKAESKFRQFNKFENGNEWVEVVIMEGLDYEQVNNYTLTLT 1183 Query: 229 AQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENV--------PIGYSIVRVQ 280 A D S S T ++ +RDVND P+F LF ++ E + G IV V+ Sbjct: 1184 ATDMTSRVASTKT-FVVEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVK 1242 Query: 281 AYDAD-EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTAT 339 A D D +G E+ Y + + G ID +G ++ + + DRE Y L V A+ Sbjct: 1243 AIDTDSDGPQNEVHYRIVG-EANGEETKHFRIDELTGEIFPNEKFDREKIDMYILTVEAS 1301 Query: 340 D-------GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392 D G + P F +Y + E E G V+T+ A D Sbjct: 1302 DRSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHD 1361 Query: 393 ADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT 452 D+ + L Y + G GR + G I V +PLDF+ +Y L + A+D G + T Sbjct: 1362 LDKHSNLRYHLIGAG-GGRIPFGVRTDSGTIFVKEPLDFEASDQYHLVLIASD-GRHNAT 1419 Query: 453 AMVQINITDANNYAPVFENAPYTASVF-EDAPIGTTVLVVSATDSDVG-INAQITYSLSS 510 V I+I D N+ AP FE Y +V ED I + V ATD+D +++I Y L Sbjct: 1420 TNVYIHIEDVNDNAPQFEQQKYATTVIEEDVDIPKVLFNVHATDADQDEKSSRIVYRLEG 1479 Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG---YLLTVTARDGGVPSLSDTTDV 567 + + D+ F I +G I K LDR+ +G + V A D L DV Sbjct: 1480 QGA-------DEVFRIGKYSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGLVGYADV 1532 Query: 568 EISVVDVNDNEPVFKQQLY---TANIMEDALVGTSVSQVGATDAD--VGLNGRIHYEL-- 620 +++V D+NDN P+F ++L+ N G V A D D N I Y + Sbjct: 1533 QVNVRDINDNSPIFPERLFGYIEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGIVR 1592 Query: 621 DPKDREEGSFVIDPASGVIRTNKALDRESVATHD--LKAVAIDGGTPPQSSTVIVHIKIE 678 + E F ID +G I ++LDRE + + ++ A D G P + V IK+ Sbjct: 1593 NKLINGESVFRIDQNTGKIFAMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIKVT 1652 Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738 D+ND+ P FE + E +PIG + A D DE V ++ + ++S+ F + Sbjct: 1653 DMNDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDADEEAKDNV-FTYQLSEESDYFYVT 1711 Query: 739 TRQGSDKAE---LVTMVDLDYE--SPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPV 793 T + S ++ L LDYE + R + L IR + + V + + D ND+AP Sbjct: 1712 TDKDSKQSSVGVLRVKQPLDYEDVTQRDGFHLGIRVSDGRHDAEAAVHVALVDRNDHAPH 1771 Query: 794 MKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLS 852 + + ++ P G GR A D D D ++RI ++ + G++ ++ Sbjct: 1772 IHG--ATEHRVREDVPRGTSIGRYTATDRDAGDTARFRINRQSDPKRQFTIDQDGTLRVA 1829 Query: 853 PQLNTNVPKLATMEVSVTDGVNEIKAMM 880 L+ + + + D N I M Sbjct: 1830 HTLDREDIAVYNLIIEAYDNSNNIGRQM 1857 Score = 243 bits (594), Expect = 6e-62 Identities = 354/1379 (25%), Positives = 560/1379 (40%), Gaps = 160/1379 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGAS--------SGTTVLTLKATDQDI-GKNAEVEYT 61 + V D ND P F + + ++ E + +G ++T+KA D D G EV Y Sbjct: 1199 VEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYR 1258 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121 I N E+ FRID +G + DREK+ Y + V+A+D Sbjct: 1259 I----VGEANGEETKH------------FRIDELTGEIFPNEKFDREKIDMYILTVEASD 1302 Query: 122 Q---ASPVSDRLSS-TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKAT 177 + A P ++ + + + I D NDN P F E+ Y V E S + + IKA Sbjct: 1303 RSVSALPGANGPNKDNVKVQIVINDVNDNAPSFEEQKYIGRVKE--SEGEGHDVITIKAH 1360 Query: 178 DADVGANSAIRYAIIG-GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS 236 D D +N +RY +IG G ++ F + + SG + + + LD+E Y LV+ A DG Sbjct: 1361 DLDKHSN--LRYHLIGAGGGRIPFGVRTDSGTIFVKEPLDFEASDQYHLVLIASDG---R 1415 Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESV-SENVPIGYSIVRVQAYDADEGV-NAELTY 294 + TT + I+I DVNDNAP+F + +V E+V I + V A DAD+ ++ + Y Sbjct: 1416 HNATTNVYIHIEDVNDNAPQFEQQKYATTVIEEDVDIPKVLFNVHATDADQDEKSSRIVY 1475 Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA---KYQLLVTATDGGDPPRSATAT 351 + + D I SG + LDR+ A + +V A D A Sbjct: 1476 RLEGQ----GADEVFRIGKYSGTIELVKALDRDPPAGVPSWNFVVQAIDDDGNGLVGYAD 1531 Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPP----GTPVVTLTATDADEDNRLHYEITGGN 407 F P + + E+ P G + + A D D+ + I G Sbjct: 1532 VQVNVRDINDNSPIF-PERLFGYIEENREPIHSDGVYFMDVQARDFDDPTTENANIEYGI 1590 Query: 408 TRGR-------FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQIN 458 R + F I G+ + + ER +++ V A D G R A V I Sbjct: 1591 VRNKLINGESVFRIDQNTGKIFAMRSLDREISSEREFIIEVRANDRGVPSREGFANVTIK 1650 Query: 459 ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI-TYSLSSEISNEAV 517 +TD N+ AP FE Y SV E APIG V+ SA D+D + TY LS E S+ Sbjct: 1651 VTDMNDNAPFFEKTRYEGSVEETAPIGAAVMSFSAFDADEEAKDNVFTYQLSEE-SDYFY 1709 Query: 518 AHHDQQFVINPQTGAITTNKLLDRETMS---GYLLTVTARDGGVPSLSDTTDVEISVVDV 574 D+ G + + LD E ++ G+ L + DG + V +++VD Sbjct: 1710 VTTDKDSK-QSSVGVLRVKQPLDYEDVTQRDGFHLGIRVSDGRHDA---EAAVHVALVDR 1765 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR--IHYELDPKDREEGSFVI 632 ND+ P + ED GTS+ + ATD D G R I+ + DPK + F I Sbjct: 1766 NDHAPHIHGAT-EHRVREDVPRGTSIGRYTATDRDAGDTARFRINRQSDPKRQ----FTI 1820 Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692 D G +R LDRE +A ++L A D V V++ +D+ND+ P + Sbjct: 1821 DQ-DGTLRVAHTLDREDIAVYNLIIEAYDNSNNIGRQMVAVYL--QDVNDNGPEPYTVPR 1877 Query: 693 TFYISENSPIGTT-IGEIRAHDPDE---GP--NAVVHYSIKGGDDSNS-FSLETRQGSDK 745 EN+P+ EIRA D D GP V S K N F+ G+ Sbjct: 1878 PCIFRENTPVNQLGTCEIRATDRDTAEFGPPFTMEVSPSFKYSQYLNVIFNANGDGGNGS 1937 Query: 746 AELVTMVDLDYESP--RKKYEL-VIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN 802 + + + D E+P K E+ +I A N+ V +++ D+NDN I N Sbjct: 1938 MTITPLQEFDREAPVPGKILEIPLILADRAGRRNEASVHVIIGDLNDNTMHDGRMTIHVN 1997 Query: 803 NYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKL 862 +Y GRV DAD D L + S ++ GS+T++ ++ Sbjct: 1998 SYLGRLKETVIGRVYVDDADDWD-LGDKTFSWKDSRPGFELSDKGSITMAGEMAAGT--- 2053 Query: 863 ATMEVSVTDGVNEIKAM--MQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGL 920 TM +V D + A+ + + V + + N +V+L + AE+ L FI Sbjct: 2054 YTMSANVHDNARDEDAVGYVTVIVNAVPQIAFDNQGSVQL--LIAEETPLQLPDDFIRAD 2111 Query: 921 A---AIIPCPKENIYIFSVQDDT-DVTGNILNVSFSARR--PDAEVGVAGDPSPHYSPTH 974 + +++ K+ + + D T DV + ++ R P V S + Sbjct: 2112 SNGQSLMDTFKQEMTAYMGGDVTVDVFSVQVGIATLQTRDVPVLNVRFNARGSTYRDTAQ 2171 Query: 975 LRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFR 1034 L + HR L R V+++ ++C C C T+ V+++S + Sbjct: 2172 LNGLIAAHRADLQRKLNVEIVGVGIDMCKFTQC--DAGCQTLNSADYDGIVVSANSTVIV 2229 Query: 1035 PIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREG--GILCQGC 1092 + + C CP C+ L C DG G C R +G G CQG Sbjct: 2230 GVNATSRDDCTCPVWRAPPACQHSL----CHNDGVCHNTNPGFFCECRNDGLKGARCQG- 2284 Query: 1093 SIDAAYTTAVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRY---- 1148 TT RSF + F + + +++ F T + LL YNG Sbjct: 2285 ------TT-------RSFGGNGFAWYKPMPACTSLNISFSFMTTQSDALLFYNGPLETLR 2331 Query: 1149 NERH----DFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGN-VGDGSWHTVEIEY 1203 N+ H D++ ++L RGG L S + G +S + V + DG+WH + + Sbjct: 2332 NDTHIEYSDYIFIQL------RGGRISLEVSMN-GQSRSSLEVASTALNDGTWHDISVNQ 2384 Query: 1204 FNRTITMILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQ 1263 + + +++D+C + L AGA D +C R E+ T L++ P+Q Sbjct: 2385 EGKRVELVVDNC-RFLG-AGADD----SSC----------RAELYTPDDDERLNIVTPVQ 2428 Query: 1264 IGGLPNIPSS---FQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSS 1319 IGGL + + GC+ + ++ DL + + + GC + C S Sbjct: 2429 IGGLAPLSGQDYPQTIPRAGLNGCVRNLNVNGDQYDLATPAFEQNSEKGCRLWGATCDS 2487 Score = 212 bits (518), Expect = 1e-52 Identities = 254/917 (27%), Positives = 386/917 (42%), Gaps = 107/917 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D ND+ P F Y A VRE T+L + A D+D G N+ + Y++ Sbjct: 630 IRIDDVNDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKDTGDNSRITYSV-------- 681 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 D + R+D A E+ Y V A D PVS L Sbjct: 682 ---DNHNFSINSNGEISAKVRLD---------ADQLNERHFVYRFNVTARDHGEPVS--L 727 Query: 131 SSTATIHVNIIDDNDNYPQF-SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 SS+A IH+ + ND F YT V ED + PVI +I+A DAD + Y Sbjct: 728 SSSAMIHIRTENTNDESAVFLPTSQYTAFVAED-AQGGTPVI-QIQARDAD---RDEVTY 782 Query: 190 AII---GGNTQMQ--FSIDSLSGDVSL---VKTLDYEQVRS-YRLVIRAQDGGS----PS 236 + + G +TQ FSID +G V L V D + + L + QD GS PS Sbjct: 783 SFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPS 842 Query: 237 RSNTT--QLLINIRDVNDNAPRFYTSLFQESVSENVPIGY-----SIVRVQAYDADEGVN 289 +++T+ LLI I DVN+N P F +++ + Y +IV+V+A D D N Sbjct: 843 KTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSAN 902 Query: 290 AELTYTMTDKDYTGNVD-LPITIDPRSGWVYTSGQL--DRETQAKYQLLVTATDGGDPPR 346 ++ Y++ YT + ID ++G + S + DRET+ + + V ATD GD P Sbjct: 903 GDIVYSLY---YTQSESRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRGDRPL 959 Query: 347 SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR------LH 400 F YE ++ E GT V+T+ A D D + L Sbjct: 960 IGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGTSVITVFAFDNDAAHNAEITYSLE 1019 Query: 401 YEITGG----NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG---GRSDTA 453 + T G N F + ++ G IT+ +P+ K + +++ V A D+G +A Sbjct: 1020 IDTTAGEEHQNDLDFFELVNRRS-GEITLIKPIPMKTQ-KFIFNVIADDNGIPEALQSSA 1077 Query: 454 MVQINITDANNYAPVFENAPYT---ASVFEDAPIGTTVLVVSATDSDVGINAQITYSL-- 508 V +N+ D AP ++ +P +V E+ + +L A S N+ + Y L Sbjct: 1078 QVTLNVLDKQQKAPKWQTSPDCKPGITVDENVELNKVILRCRAVSSGDSRNSDVIYKLTA 1137 Query: 509 SSEISNEAVAHHDQ--QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566 S N+A + Q +F + + + LD E ++ Y LT+TA D ++ T Sbjct: 1138 SGGPGNKAESKFRQFNKFENGNEWVEVVIMEGLDYEQVNNYTLTLTATD-MTSRVASTKT 1196 Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALV--------GTSVSQVGATDADV-GLNGRIH 617 + V DVND P F L+T I E+ G + V A D D G +H Sbjct: 1197 FVVEVRDVNDVVPQFTVDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVH 1256 Query: 618 YEL--DPKDREEGSFVIDPASGVIRTNKALDRE-------SVATHDLKAVAIDGGTPPQS 668 Y + + E F ID +G I N+ DRE +V D A+ G P Sbjct: 1257 YRIVGEANGEETKHFRIDELTGEIFPNEKFDREKIDMYILTVEASDRSVSALPGANGPNK 1316 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 V V I I D+ND+ P FE + E+ G + I+AHD D+ N H I Sbjct: 1317 DNVKVQIVINDVNDNAPSFEEQKYIGRVKESEGEGHDVITIKAHDLDKHSNLRYHL-IGA 1375 Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVN 788 G F + T D + LD+E+ +Y LV+ A+ V I + DVN Sbjct: 1376 GGGRIPFGVRT----DSGTIFVKEPLDFEA-SDQYHLVLIASDGRHNATTNVYIHIEDVN 1430 Query: 789 DNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADVTDK---LQYRILSGNNANLIL-LN 843 DNAP + + ++ + V A DAD +K + YR L G A+ + + Sbjct: 1431 DNAPQFEQQKYATTVIEEDVDIPKVLFNVHATDADQDEKSSRIVYR-LEGQGADEVFRIG 1489 Query: 844 ETTGSMTLSPQLNTNVP 860 + +G++ L L+ + P Sbjct: 1490 KYSGTIELVKALDRDPP 1506 Score = 200 bits (487), Expect = 6e-49 Identities = 212/752 (28%), Positives = 327/752 (43%), Gaps = 63/752 (8%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F +D +SG + T S E+ Y + +A D SP + S + + + I ++ PQ Sbjct: 472 FIVDPKSGVVRTGWS-KYERGDTYRISAQAMD-LSPSDNTTSQLSEVAILEILADERPPQ 529 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDA--DVGANSAIRYAIIGGNTQMQ---FSIDS 204 F+++ Y V+V ED V + V K ++ + D + I Y++ G + + F ID Sbjct: 530 FAKQEYEVTVSEDNLVDYSVVDVKAQSFRSFEDGRSKGPITYSLEGDTPEDETKWFRIDP 589 Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 +G + L + LD++ +L +R + L I I DVNDN P F L+ Sbjct: 590 STGIIHLTRLLDFDDPALPKLHKLKVTAREDNRESHVDLTIRIDDVNDNVPTFTRPLYTA 649 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 V E++P+ +I++V A D D G N+ +TY++ + +++ N + I+ R + QL Sbjct: 650 QVREDIPLNQTILKVTAVDKDTGDNSRITYSVDNHNFSINSNGEISAKVR----LDADQL 705 Query: 325 DRETQAKYQLLVTATDGGDP-PRSATATXXXXXXXXXXXXXXFMP-GQYEVELAEDEPPG 382 + E Y+ VTA D G+P S++A F+P QY +AED G Sbjct: 706 N-ERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTNDESAVFLPTSQYTAFVAEDAQGG 764 Query: 383 TPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNGRGLITVAQPLD----FKQERR 436 TPV+ + A DAD D + + G +T+ + GL+ + + + E Sbjct: 765 TPVIQIQARDADRDEVTYSFMDKNGRSTQKMNLFSIDEHTGLVKLRHGVSAADLAEAENP 824 Query: 437 YVLTVSATDSGG--------RSDTAMVQINITDANNYAPVFEN-APYT--ASVFEDA--P 483 LTV D G + A + I I D NN P F + A Y+ A + E Sbjct: 825 INLTVIVQDDGSCCVYPSKTHTSYATLLIGIEDVNNNKPEFPDCAKYSDIAKIMEGTYKT 884 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK--LLDR 541 T++ V ATD D N I YSL S A FVI+ QTG +T + + DR Sbjct: 885 DPPTIVKVEATDDDSSANGDIVYSLYYTQSESRKA-----FVIDRQTGVLTPSPHVVFDR 939 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 ET +TV A D G L + VVD+NDN P F++ Y ++ VGTSV Sbjct: 940 ETRPREDVTVKATDRGDRPLIGFCQFSVEVVDINDNSPQFERPSYETSVSRFEAVGTSVI 999 Query: 602 QVGATDADVGLNGRIHY--ELDPKDREEGS------FVIDPASGVIRTNKALDRESVATH 653 V A D D N I Y E+D EE +++ SG I K + ++ Sbjct: 1000 TVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDFFELVNRRSGEITLIKPIPMKT-QKF 1058 Query: 654 DLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPVFES--DCLT-FYISENSPIGTTIGEI 709 +A D G P S+ V + + D P +++ DC + EN + I Sbjct: 1059 IFNVIADDNGIPEALQSSAQVTLNVLDKQQKAPKWQTSPDCKPGITVDENVELNKVILRC 1118 Query: 710 RAHDPDEGPNAVVHYSI-KGGDDSNSFSLETRQ------GSDKAELVTMVDLDYESPRKK 762 RA + N+ V Y + G N + RQ G++ E+V M LDYE Sbjct: 1119 RAVSSGDSRNSDVIYKLTASGGPGNKAESKFRQFNKFENGNEWVEVVIMEGLDYEQV-NN 1177 Query: 763 YELVIRAA--SPPLWNDVRVEILVTDVNDNAP 792 Y L + A + + + + V DVND P Sbjct: 1178 YTLTLTATDMTSRVASTKTFVVEVRDVNDVVP 1209 Score = 197 bits (480), Expect = 4e-48 Identities = 235/890 (26%), Positives = 384/890 (43%), Gaps = 100/890 (11%) Query: 17 NDHSPVFEMQQYEASVREGASSGTTVLTLKATD----QDIGKNAEVEYTIELVTADTLNP 72 ++ P F Q+YE +V E +V+ +KA +D + Y++E DT P Sbjct: 524 DERPPQFAKQEYEVTVSEDNLVDYSVVDVKAQSFRSFEDGRSKGPITYSLE---GDT--P 578 Query: 73 EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132 ED FRID +G + LD + A L K + + D S Sbjct: 579 EDETKW-----------FRIDPSTGIIHLTRLLDFDDPA-LPKLHKL--KVTAREDNRES 624 Query: 133 TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII 192 + + I D NDN P F+ YT V EDI + N I K+ A D D G NS I Y++ Sbjct: 625 HVDLTIRIDDVNDNVPTFTRPLYTAQVREDIPL--NQTILKVTAVDKDTGDNSRITYSVD 682 Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRS----YRLVIRAQDGGSP-SRSNTTQLLINI 247 N FSI+S +G++S LD +Q+ YR + A+D G P S S++ + I Sbjct: 683 NHN----FSINS-NGEISAKVRLDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRT 737 Query: 248 RDVNDNAPRFY-TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + ND + F TS + V+E+ G ++++QA DAD E+TY+ DK+ Sbjct: 738 ENTNDESAVFLPTSQYTAFVAEDAQGGTPVIQIQARDADRD---EVTYSFMDKNGRSTQK 794 Query: 307 LPI-TIDPRSGWVY----TSGQLDRETQAKYQLLVTATDGGD----PPRSAT--ATXXXX 355 + + +ID +G V S E + L V D G P ++ T AT Sbjct: 795 MNLFSIDEHTGLVKLRHGVSAADLAEAENPINLTVIVQDDGSCCVYPSKTHTSYATLLIG 854 Query: 356 XXXXXXXXXXFMPGQYEVELA-------EDEPPGTPVVTLTATDADEDNRLHYEITGGNT 408 F ++A + +PP V T D+ + + Y + + Sbjct: 855 IEDVNNNKPEFPDCAKYSDIAKIMEGTYKTDPPTIVKVEATDDDSSANGDIVYSLYYTQS 914 Query: 409 RGRFSITSQNGRGLITVAQPLDFKQER--RYVLTVSATDSGGRSDTAMVQ--INITDANN 464 R + G++T + + F +E R +TV ATD G R Q + + D N+ Sbjct: 915 ESRKAFVIDRQTGVLTPSPHVVFDRETRPREDVTVKATDRGDRPLIGFCQFSVEVVDIND 974 Query: 465 YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524 +P FE Y SV +GT+V+ V A D+D NA+ITYSL + + +D F Sbjct: 975 NSPQFERPSYETSVSRFEAVGTSVITVFAFDNDAAHNAEITYSLEIDTTAGEEHQNDLDF 1034 Query: 525 --VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVF 581 ++N ++G IT K + +T ++ V A D G+P +L + V ++V+D P + Sbjct: 1035 FELVNRRSGEITLIKPIPMKTQK-FIFNVIADDNGIPEALQSSAQVTLNVLDKQQKAPKW 1093 Query: 582 KQQ---LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL----DPKDREEGSF---- 630 + + E+ + + + A + N + Y+L P ++ E F Sbjct: 1094 QTSPDCKPGITVDENVELNKVILRCRAVSSGDSRNSDVIYKLTASGGPGNKAESKFRQFN 1153 Query: 631 VIDPASGVIRT--NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688 + + + + LD E V + L A D T +ST +++ D+ND P F Sbjct: 1154 KFENGNEWVEVVIMEGLDYEQVNNYTLTLTATD-MTSRVASTKTFVVEVRDVNDVVPQFT 1212 Query: 689 SDCLTFYISE----NSPIGTTIGE----IRAHDPD-EGPNAVVHYSIKG---GDDSNSFS 736 D T I E N + T G+ ++A D D +GP VHY I G G+++ F Sbjct: 1213 VDLFTGTIDEEMTPNEHLEKTNGKPIVTVKAIDTDSDGPQNEVHYRIVGEANGEETKHFR 1272 Query: 737 LETRQG----SDK--AELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDN 790 ++ G ++K E + M L E+ + + A+ P ++V+V+I++ DVNDN Sbjct: 1273 IDELTGEIFPNEKFDREKIDMYILTVEASDRSVS-ALPGANGPNKDNVKVQIVINDVNDN 1331 Query: 791 APVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANL 839 AP ++ Q K+ G + A+D D L+Y ++ + Sbjct: 1332 APSFEE-QKYIGRVKESEGEGHDVITIKAHDLDKHSNLRYHLIGAGGGRI 1380 Score = 101 bits (243), Expect = 2e-19 Identities = 120/489 (24%), Positives = 215/489 (43%), Gaps = 45/489 (9%) Query: 389 TATDADEDNRLHYEITGGNTRGRFSITSQ----NGRGLITVAQPLDFKQERRYVLTVSAT 444 T + E + + G T G ++ + + G I + +PL++++ + TV Sbjct: 340 TTMEDIEKKDMKIPLFAGETIGEINVAKEWLKIDDDGKIHLLKPLNYEKTSSIIATVPIN 399 Query: 445 DSGGRSDTAMVQINITDANNYAPVFENAPYT--ASVFEDAPIGTTVLVVSATDSDVGINA 502 + T ++I++ D + P F N+P A V + IG V A D ++ Sbjct: 400 GLQS-TRTQTIRIHVADIDE-PPSFVNSPLPMLAVVPLNPTIGRIVYQFVARDEHGDGDS 457 Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 + Y I + F+++P++G + T E Y ++ A D PS + Sbjct: 458 NVLYKTIDVIPAGS-------FIVDPKSGVVRTG-WSKYERGDTYRISAQAMDLS-PSDN 508 Query: 563 DTTDV-EISVVDV--NDNEPVFKQQLYTANIMEDALVGTSVSQVGATD----ADVGLNGR 615 T+ + E++++++ ++ P F +Q Y + ED LV SV V A D G Sbjct: 509 TTSQLSEVAILEILADERPPQFAKQEYEVTVSEDNLVDYSVVDVKAQSFRSFEDGRSKGP 568 Query: 616 IHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673 I Y L D + E F IDP++G+I + LD + A L + + + S V + Sbjct: 569 ITYSLEGDTPEDETKWFRIDPSTGIIHLTRLLDFDDPALPKLHKLKVTAREDNRESHVDL 628 Query: 674 HIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN 733 I+I+D+ND+ P F T + E+ P+ TI ++ A D D G N+ + YS+ D++ Sbjct: 629 TIRIDDVNDNVPTFTRPLYTAQVREDIPLNQTILKVTAVDKDTGDNSRITYSV----DNH 684 Query: 734 SFSLETRQGSDKAELVTMVDLDYESPRK---KYELVIRAASPP--LWNDVRVEILVTDVN 788 +FS+ + G A++ +D D + R ++ + R P L + + I + N Sbjct: 685 NFSINS-NGEISAKV--RLDADQLNERHFVYRFNVTARDHGEPVSLSSSAMIHIRTENTN 741 Query: 789 DNAPV-MKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGN-----NANLILL 842 D + V + Q +D P ++ A DAD D++ Y + N NL + Sbjct: 742 DESAVFLPTSQYTAFVAEDAQGGTPVIQIQARDAD-RDEVTYSFMDKNGRSTQKMNLFSI 800 Query: 843 NETTGSMTL 851 +E TG + L Sbjct: 801 DEHTGLVKL 809 >UniRef50_Q4S488 Cluster: Chromosome undetermined SCAF14743, whole genome shotgun sequence; n=2; cellular organisms|Rep: Chromosome undetermined SCAF14743, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 2087 Score = 258 bits (631), Expect = 2e-66 Identities = 210/673 (31%), Positives = 312/673 (46%), Gaps = 42/673 (6%) Query: 40 TTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL 99 T TL+ Q++ +T V +N V + + G S A Sbjct: 566 TGFFTLRVRVQNVASVPLASFTTVYVNVTDVNDNVPFFLSSTYEATVPEGAQT-GTSVAQ 624 Query: 100 LTRASLDR--EKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTV 157 ++ A LD RY +L + S A + D E Y V Sbjct: 625 VSAADLDSGPHGTVRYLILRDDSGDWRFFDIDSLSGAIVSRASFDREQKASYLLESLYEV 684 Query: 158 SVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDY 217 SV+ED V VI + A D D GAN+ +RY I GN+ F ++ G + + + LDY Sbjct: 685 SVEEDKEV--GFVIITVTANDEDEGANAKLRYQIAAGNSMGAFDVEPEVGTIFVARPLDY 742 Query: 218 EQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP-IGYSI 276 E R Y+L + A DG N T +++ + + ND AP F S + +V+E + + I Sbjct: 743 EAERRYQLRLVASDG---KWENETLVVVEVLNRNDEAPVFSQSQYHAAVTEELSQLPVLI 799 Query: 277 VRVQAYDAD-EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL 335 ++V A D D E L Y++ + G T+D RSG +Y +LDRE + ++ L Sbjct: 800 LQVSATDPDQEADQGALRYSLHGQGAGGE----FTVDQRSGSIYAHRRLDREERPTWRFL 855 Query: 336 VTATDGGDPPRSATATXXXXXXXXXXXXXXF------MPGQYEVELAEDEPPGTPVVTLT 389 V ATD G + A F G + +AE+ P T V+ + Sbjct: 856 VLATDEGGAGLTGFADVLLEVRDVNDNAPFFPCPALQAEGCFVGRVAENSPADTSVMEMR 915 Query: 390 ATDADEDNR-----LHYEITGGNTRGRFSIT--SQNGR-GLI-TVAQPLDFKQERRYVLT 440 ATD D+ N L Y I N R + ++ S NG G I TV + LD ++ R+++ Sbjct: 916 ATDLDDPNVGANAILTYSIIQ-NVRNQINLNLFSINGATGTIYTVLRSLDREEAERHLVV 974 Query: 441 VSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 V A D G + T I ++D N++APVF Y+A V ED +G+ VLVVSA D D G Sbjct: 975 VEARDGEGLAGTGTATIIVSDVNDHAPVFTQRLYSAQVTEDLEVGSQVLVVSAMDQDEGQ 1034 Query: 501 NAQITYSL-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG--YLLTVTARDGG 557 NA +T+S+ + + D+ +N + G I K +D E + LTV A D Sbjct: 1035 NAAVTFSIVGGDEDRKFFLETDR---VN-RRGVIRLQKKVDFEKPQERVFNLTVKAEDSD 1090 Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLY-TANIMEDALVGTSVSQVGATDADVGLNGRI 616 SLS + V D ND+ PVF Q Y A + ED GT V+QV A+DAD G NGR+ Sbjct: 1091 FFSLSSCL---VRVEDANDHAPVFSPQFYEAAALSEDTAAGTIVTQVTASDADSGQNGRL 1147 Query: 617 HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676 Y + + G F++D SG + +LDRE + H + +A D GTP + T ++ + Sbjct: 1148 SYSISRQSDPLGQFLVD-QSGWVLLAGSLDREKTSQHRILLLATDAGTPALTGTAVLIVT 1206 Query: 677 IEDINDSPPVFES 689 + D+ND+ P FE+ Sbjct: 1207 VLDVNDNGPEFEA 1219 Score = 209 bits (510), Expect = 1e-51 Identities = 178/567 (31%), Positives = 260/567 (45%), Gaps = 43/567 (7%) Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D A SL++ SV E+ +G+ I+ V A D DEG NA+L Y + + G D Sbjct: 669 DREQKASYLLESLYEVSVEEDKEVGFVIITVTANDEDEGANAKLRYQIAAGNSMGAFD-- 726 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 ++P G ++ + LD E + +YQL + A+DG + F Sbjct: 727 --VEPEVGTIFVARPLDYEAERRYQLRLVASDGKWENETLVVVEVLNRNDEAPV---FSQ 781 Query: 369 GQYEVELAEDEPPGTPVVTL--TATDADED---NRLHYEITGGNTRGRFSITSQNGRGLI 423 QY + E E PV+ L +ATD D++ L Y + G G F++ ++G I Sbjct: 782 SQYHAAVTE-ELSQLPVLILQVSATDPDQEADQGALRYSLHGQGAGGEFTVDQRSGS--I 838 Query: 424 TVAQPLDFKQERRYVLTVSATDSGGRSDT--AMVQINITDANNYAPVFE------NAPYT 475 + LD ++ + V ATD GG T A V + + D N+ AP F + Sbjct: 839 YAHRRLDREERPTWRFLVLATDEGGAGLTGFADVLLEVRDVNDNAPFFPCPALQAEGCFV 898 Query: 476 ASVFEDAPIGTTVLVVSATDSD---VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 V E++P T+V+ + ATD D VG NA +TYS+ + N+ + F IN TG Sbjct: 899 GRVAENSPADTSVMEMRATDLDDPNVGANAILTYSIIQNVRNQINLN---LFSINGATGT 955 Query: 533 I-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 I T + LDRE +L+ V ARDG L+ T I V DVND+ PVF Q+LY+A + Sbjct: 956 IYTVLRSLDREEAERHLVVVEARDG--EGLAGTGTATIIVSDVNDHAPVFTQRLYSAQVT 1013 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV-IDPAS--GVIRTNKALDRE 648 ED VG+ V V A D D G N + + + D + F+ D + GVIR K +D E Sbjct: 1014 EDLEVGSQVLVVSAMDQDEGQNAAVTFSIVGGDEDRKFFLETDRVNRRGVIRLQKKVDFE 1073 Query: 649 SVATH--DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL-TFYISENSPIGTT 705 +L A D SS ++ ++ED ND PVF +SE++ GT Sbjct: 1074 KPQERVFNLTVKAEDSDFFSLSSCLV---RVEDANDHAPVFSPQFYEAAALSEDTAAGTI 1130 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765 + ++ A D D G N + YSI D L + G L +D + S + L Sbjct: 1131 VTQVTASDADSGQNGRLSYSISRQSDPLGQFLVDQSG--WVLLAGSLDREKTSQHRILLL 1188 Query: 766 VIRAASPPLWNDVRVEILVTDVNDNAP 792 A +P L + + V DVNDN P Sbjct: 1189 ATDAGTPALTGTAVLIVTVLDVNDNGP 1215 Score = 205 bits (501), Expect = 1e-50 Identities = 142/441 (32%), Positives = 230/441 (52%), Gaps = 30/441 (6%) Query: 371 YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 YEV + ED+ G ++T+TA D DE + +L Y+I GN+ G F + + G I VA+P Sbjct: 682 YEVSVEEDKEVGFVIITVTANDEDEGANAKLRYQIAAGNSMGAFDVEPEVGT--IFVARP 739 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED-APIGTT 487 LD++ ERRY L + A+D ++T +V + + + N+ APVF + Y A+V E+ + + Sbjct: 740 LDYEAERRYQLRLVASDGKWENETLVV-VEVLNRNDEAPVFSQSQYHAAVTEELSQLPVL 798 Query: 488 VLVVSATDSDVGIN-AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 +L VSATD D + + YSL + + +F ++ ++G+I ++ LDRE Sbjct: 799 ILQVSATDPDQEADQGALRYSLHGQGAGG-------EFTVDQRSGSIYAHRRLDREERPT 851 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK------QQLYTANIMEDALVGTSV 600 + V A D G L+ DV + V DVNDN P F + + + E++ TSV Sbjct: 852 WRFLVLATDEGGAGLTGFADVLLEVRDVNDNAPFFPCPALQAEGCFVGRVAENSPADTSV 911 Query: 601 SQVGATDAD---VGLNGRIHYELDPKDREE---GSFVIDPASGVIRTN-KALDRESVATH 653 ++ ATD D VG N + Y + R + F I+ A+G I T ++LDRE H Sbjct: 912 MEMRATDLDDPNVGANAILTYSIIQNVRNQINLNLFSINGATGTIYTVLRSLDREEAERH 971 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713 + A DG + T I + D+ND PVF + ++E+ +G+ + + A D Sbjct: 972 LVVVEARDGEGLAGTGTAT--IIVSDVNDHAPVFTQRLYSAQVTEDLEVGSQVLVVSAMD 1029 Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK-YELVIRAASP 772 DEG NA V +SI GGD+ F LET + + + + +D+E P+++ + L ++A Sbjct: 1030 QDEGQNAAVTFSIVGGDEDRKFFLETDRVNRRGVIRLQKKVDFEKPQERVFNLTVKAEDS 1089 Query: 773 PLWNDVRVEILVTDVNDNAPV 793 ++ + V D ND+APV Sbjct: 1090 DFFSLSSCLVRVEDANDHAPV 1110 Score = 145 bits (351), Expect = 2e-32 Identities = 138/483 (28%), Positives = 234/483 (48%), Gaps = 50/483 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASS-GTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 + VL+ ND +PVF QY A+V E S +L + ATD D + A+ + + Sbjct: 767 VEVLNRNDEAPVFSQSQYHAAVTEELSQLPVLILQVSATDPD--QEAD-----QGALRYS 819 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L+ + A F +D RSG++ LDRE+ + LV ATD+ Sbjct: 820 LHGQGAGGE-----------FTVDQRSGSIYAHRRLDREERPTWRFLVLATDEGGA---G 865 Query: 130 LSSTATIHVNIIDDNDNYPQF------SEKTYTVSVDEDISVTDNPVIAKIKATDAD--- 180 L+ A + + + D NDN P F +E + V E+ S D V+ +++ATD D Sbjct: 866 LTGFADVLLEVRDVNDNAPFFPCPALQAEGCFVGRVAEN-SPADTSVM-EMRATDLDDPN 923 Query: 181 VGANSAIRYAIIGG-NTQMQ---FSIDSLSGDV-SLVKTLDYEQVRSYRLVIRAQDGGSP 235 VGAN+ + Y+II Q+ FSI+ +G + +++++LD E+ + +V+ A+DG Sbjct: 924 VGANAILTYSIIQNVRNQINLNLFSINGATGTIYTVLRSLDREEAERHLVVVEARDGEGL 983 Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295 + + T ++++ DVND+AP F L+ V+E++ +G ++ V A D DEG NA +T++ Sbjct: 984 AGTGTATIIVS--DVNDHAPVFTQRLYSAQVTEDLEVGSQVLVVSAMDQDEGQNAAVTFS 1041 Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355 + D L R G + ++D E + +T D + ++ Sbjct: 1042 IVGGDEDRKFFLETDRVNRRGVIRLQKKVDFEKPQERVFNLTVK-AEDSDFFSLSSCLVR 1100 Query: 356 XXXXXXXXXXFMPGQYEVE-LAEDEPPGTPVVTLTATDAD--EDNRLHYEITG-GNTRGR 411 F P YE L+ED GT V +TA+DAD ++ RL Y I+ + G+ Sbjct: 1101 VEDANDHAPVFSPQFYEAAALSEDTAAGTIVTQVTASDADSGQNGRLSYSISRQSDPLGQ 1160 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVF 469 F + G + +A LD ++ ++ + + ATD+G + TA++ + + D N+ P F Sbjct: 1161 FLVDQS---GWVLLAGSLDREKTSQHRILLLATDAGTPALTGTAVLIVTVLDVNDNGPEF 1217 Query: 470 ENA 472 E A Sbjct: 1218 EAA 1220 Score = 101 bits (241), Expect = 4e-19 Identities = 71/231 (30%), Positives = 114/231 (49%), Gaps = 9/231 (3%) Query: 433 QERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492 Q R V + A+D G RS + + + IT+ +N P ++ Y +V E+ ++ + Sbjct: 455 QTSRIVRQIVASDGGNRSSSVELTVFITNVHNQPPQWDQPEYWVTVPENTVRDAKIVTIK 514 Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ----TGAITTNKLLDRETMSGYL 548 AT S +G + ++TY L E + +F + P + +I + LD ET + Sbjct: 515 AT-SPLG-DPRVTYDL--EEGQVPETNMPVRFYVKPNRADGSASILVAENLDFETTGFFT 570 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 L V ++ L+ T V ++V DVNDN P F Y A + E A GTSV+QV A D Sbjct: 571 LRVRVQNVASVPLASFTTVYVNVTDVNDNVPFFLSSTYEATVPEGAQTGTSVAQVSAADL 630 Query: 609 DVGLNGRIHYELDPKDREEGSFV-IDPASGVIRTNKALDRESVATHDLKAV 658 D G +G + Y + D + F ID SG I + + DRE A++ L+++ Sbjct: 631 DSGPHGTVRYLILRDDSGDWRFFDIDSLSGAIVSRASFDREQKASYLLESL 681 Score = 95.5 bits (227), Expect = 2e-17 Identities = 125/468 (26%), Positives = 199/468 (42%), Gaps = 57/468 (12%) Query: 336 VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395 + A+DGG+ RS++ + +Y V + E+ +VT+ AT Sbjct: 463 IVASDGGN--RSSSVELTVFITNVHNQPPQWDQPEYWVTVPENTVRDAKIVTIKATSPLG 520 Query: 396 DNRLHYEITGG-----NTRGRFSI--TSQNGRGLITVAQPLDFKQERRYVLTVSATD--S 446 D R+ Y++ G N RF + +G I VA+ LDF+ + L V + S Sbjct: 521 DPRVTYDLEEGQVPETNMPVRFYVKPNRADGSASILVAENLDFETTGFFTLRVRVQNVAS 580 Query: 447 GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506 + V +N+TD N+ P F ++ Y A+V E A GT+V VSA D D G + + Y Sbjct: 581 VPLASFTTVYVNVTDVNDNVPFFLSSTYEATVPEGAQTGTSVAQVSAADLDSGPHGTVRY 640 Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566 + + S + + F I+ +GAI + DRE + YLL SL Sbjct: 641 LILRDDSGDW-----RFFDIDSLSGAIVSRASFDREQKASYLL---------ESL----- 681 Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE 626 E+SV + D E F TAN ++ Q+ A N ++++P E Sbjct: 682 YEVSVEE--DKEVGFVIITVTANDEDEGANAKLRYQIAAG------NSMGAFDVEP---E 730 Query: 627 EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686 G+ + + LD E+ + L+ VA DG ++ T++V +++ + ND PV Sbjct: 731 VGTIFV---------ARPLDYEAERRYQLRLVASDGKW--ENETLVV-VEVLNRNDEAPV 778 Query: 687 F-ESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSD 744 F +S E S + I ++ A DPD E + YS+ G F+++ R GS Sbjct: 779 FSQSQYHAAVTEELSQLPVLILQVSATDPDQEADQGALRYSLHGQGAGGEFTVDQRSGSI 838 Query: 745 KAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP 792 A +D + + L L V + V DVNDNAP Sbjct: 839 YAH--RRLDREERPTWRFLVLATDEGGAGLTGFADVLLEVRDVNDNAP 884 Score = 79.4 bits (187), Expect = 1e-12 Identities = 62/213 (29%), Positives = 110/213 (51%), Gaps = 15/213 (7%) Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SS+ + V I + ++ PQ+ + Y V+V E+ +V D ++ IKAT + +G + + Y Sbjct: 472 SSSVELTVFITNVHNQPPQWDQPEYWVTVPEN-TVRDAKIVT-IKAT-SPLG-DPRVTYD 527 Query: 191 IIGG-----NTQMQFSI--DSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 + G N ++F + + G S++ + LD+E + L +R Q+ S ++ T Sbjct: 528 LEEGQVPETNMPVRFYVKPNRADGSASILVAENLDFETTGFFTLRVRVQNVASVPLASFT 587 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 + +N+ DVNDN P F +S ++ +V E G S+ +V A D D G + + Y + +D Sbjct: 588 TVYVNVTDVNDNVPFFLSSTYEATVPEGAQTGTSVAQVSAADLDSGPHGTVRYLIL-RDD 646 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQL 334 +G+ ID SG + + DRE +A Y L Sbjct: 647 SGDWRF-FDIDSLSGAIVSRASFDREQKASYLL 678 Score = 72.1 bits (169), Expect = 2e-10 Identities = 44/120 (36%), Positives = 59/120 (49%), Gaps = 6/120 (5%) Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 P N A V E+ P GT VL V A D+D+G+N Q+ Y + + + V+ F I Sbjct: 130 PQCHNYSQRAVVLENQPPGTGVLRVQAQDADLGVNGQVKYGI---MHRDGVS---SGFHI 183 Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586 +P G ITT DRE + L+VTA D L + + V D NDNEP F+ Y Sbjct: 184 DPDAGYITTTVSFDRERQREFTLSVTATDQADEPLIGICQITVLVADQNDNEPKFENSRY 243 Score = 68.1 bits (159), Expect = 3e-09 Identities = 60/239 (25%), Positives = 103/239 (43%), Gaps = 10/239 (4%) Query: 454 MVQINITDANNYAPVFENAPYTAS-VFEDAPIGTTVL--VVSATDSDVGINAQITYSLSS 510 +V + +TD N+ P F +A Y+ V E P GT++L ++ S Y+L+ Sbjct: 9 LVVVQVTDQNDCTPEFLHAIYSRDGVPESVPAGTSLLQGIIKLRRSPPPRLRGPQYTLNI 68 Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570 +++ + F ++ I + D L V G P + + + Sbjct: 69 TATDDNAS--GGPFPLSSSAQVIVG--INDVNNNKPVFLEVRGPRGRAPGVGPQGPLPLL 124 Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630 + + + Q+ A ++E+ GT V +V A DAD+G+NG++ Y + +D F Sbjct: 125 HLRLFPQCHNYSQR---AVVLENQPPGTGVLRVQAQDADLGVNGQVKYGIMHRDGVSSGF 181 Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES 689 IDP +G I T + DRE L A D P + + + D ND+ P FE+ Sbjct: 182 HIDPDAGYITTTVSFDRERQREFTLSVTATDQADEPLIGICQITVLVADQNDNEPKFEN 240 Score = 68.1 bits (159), Expect = 3e-09 Identities = 64/275 (23%), Positives = 116/275 (42%), Gaps = 21/275 (7%) Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610 + A DGG + S + ++ + + +V++ P + Q Y + E+ + + + AT + + Sbjct: 463 IVASDGG--NRSSSVELTVFITNVHNQPPQWDQPEYWVTVPENTVRDAKIVTIKAT-SPL 519 Query: 611 GLNGRIHYELD----PKDREEGSFVIDP----ASGVIRTNKALDRESVATHDLKAVAIDG 662 G + R+ Y+L+ P+ F + P S I + LD E+ L+ + Sbjct: 520 G-DPRVTYDLEEGQVPETNMPVRFYVKPNRADGSASILVAENLDFETTGFFTLRVRVQNV 578 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 + P +S V++ + D+ND+ P F S + E + GT++ ++ A D D GP+ V Sbjct: 579 ASVPLASFTTVYVNVTDVNDNVPFFLSSTYEATVPEGAQTGTSVAQVSAADLDSGPHGTV 638 Query: 723 HYSIKGGD--DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRV 780 Y I D D F +++ G+ +V+ D E + S +V Sbjct: 639 RYLILRDDSGDWRFFDIDSLSGA----IVSRASFDREQKASYLLESLYEVSVEEDKEVGF 694 Query: 781 EILVTDVND---NAPVMKDFQIIFNNYKDCFPVGP 812 I+ ND A +QI N F V P Sbjct: 695 VIITVTANDEDEGANAKLRYQIAAGNSMGAFDVEP 729 Score = 65.3 bits (152), Expect = 2e-08 Identities = 35/80 (43%), Positives = 47/80 (58%), Gaps = 3/80 (3%) Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325 V EN P G ++RVQA DAD GVN ++ Y + +D V IDP +G++ T+ D Sbjct: 141 VLENQPPGTGVLRVQAQDADLGVNGQVKYGIMHRD---GVSSGFHIDPDAGYITTTVSFD 197 Query: 326 RETQAKYQLLVTATDGGDPP 345 RE Q ++ L VTATD D P Sbjct: 198 RERQREFTLSVTATDQADEP 217 Score = 59.3 bits (137), Expect = 2e-06 Identities = 45/135 (33%), Positives = 65/135 (48%), Gaps = 19/135 (14%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NV D ND+ P F YEA+V EGA +GT+V + A D D G + V Y I L Sbjct: 591 VNVTDVNDNVPFFLSSTYEATVPEGAQTGTSVAQVSAADLDSGPHGTVRYLI-------L 643 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F ID SGA+++RAS DRE+ A Y L+++ + S D+ Sbjct: 644 RDDSGDWR----------FFDIDSLSGAIVSRASFDREQKASY--LLESLYEVSVEEDKE 691 Query: 131 SSTATIHVNIIDDND 145 I V D+++ Sbjct: 692 VGFVIITVTANDEDE 706 Score = 55.6 bits (128), Expect = 2e-05 Identities = 30/102 (29%), Positives = 51/102 (50%), Gaps = 2/102 (1%) Query: 171 IAKIKATDADVGANSAIRYAIIGGN-TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA 229 + +++A DAD+G N ++Y I+ + F ID +G ++ + D E+ R + L + A Sbjct: 151 VLRVQAQDADLGVNGQVKYGIMHRDGVSSGFHIDPDAGYITTTVSFDRERQREFTLSVTA 210 Query: 230 QDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271 D Q+ + + D NDN P+F S +Q S E P Sbjct: 211 TDQADEPLIGICQITVLVADQNDNEPKFENSRYQ-STQEATP 251 Score = 54.8 bits (126), Expect = 3e-05 Identities = 33/103 (32%), Positives = 52/103 (50%), Gaps = 5/103 (4%) Query: 696 ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755 + E+ +G I + A+D DEG NA + Y I G+ +F +E G+ + LD Sbjct: 686 VEEDKEVGFVIITVTANDEDEGANAKLRYQIAAGNSMGAFDVEPEVGT----IFVARPLD 741 Query: 756 YESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQ 798 YE+ R+ Y+L + A+ N+ V + V + ND APV Q Sbjct: 742 YEAERR-YQLRLVASDGKWENETLVVVEVLNRNDEAPVFSQSQ 783 Score = 54.0 bits (124), Expect = 6e-05 Identities = 42/126 (33%), Positives = 55/126 (43%), Gaps = 21/126 (16%) Query: 30 ASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDV 89 A V E GT VL ++A D D+G N +V+Y I V Sbjct: 139 AVVLENQPPGTGVLRVQAQDADLGVNGQVKYGI------------------MHRDGVSSG 180 Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F ID +G + T S DRE+ +T+ V ATDQA + L I V + D NDN P+ Sbjct: 181 FHIDPDAGYITTTVSFDRERQREFTLSVTATDQA---DEPLIGICQITVLVADQNDNEPK 237 Query: 150 FSEKTY 155 F Y Sbjct: 238 FENSRY 243 Score = 47.2 bits (107), Expect = 0.007 Identities = 62/239 (25%), Positives = 97/239 (40%), Gaps = 25/239 (10%) Query: 567 VEISVVDVNDNEPVFKQQLYTAN-IMEDALVGTSVSQVGATDADVGLNGRIH---YELDP 622 V + V D ND P F +Y+ + + E GTS+ Q G R+ Y L+ Sbjct: 10 VVVQVTDQNDCTPEFLHAIYSRDGVPESVPAGTSLLQ-GIIKLRRSPPPRLRGPQYTLNI 68 Query: 623 KDREE----GSFVIDPASGVI-RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 ++ G F + ++ VI N + + V G PQ ++H+++ Sbjct: 69 TATDDNASGGPFPLSSSAQVIVGINDVNNNKPVFLEVRGPRGRAPGVGPQGPLPLLHLRL 128 Query: 678 EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD-SNSFS 736 P + + EN P GT + ++A D D G N V Y I D S+ F Sbjct: 129 F------PQCHNYSQRAVVLENQPPGTGVLRVQAQDADLGVNGQVKYGIMHRDGVSSGFH 182 Query: 737 LETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792 ++ D + T V D E R ++ L + A A PL ++ +LV D NDN P Sbjct: 183 ID----PDAGYITTTVSFDRERQR-EFTLSVTATDQADEPLIGICQITVLVADQNDNEP 236 Score = 47.2 bits (107), Expect = 0.007 Identities = 35/107 (32%), Positives = 55/107 (51%), Gaps = 9/107 (8%) Query: 377 EDEPPGTPVVTLTATDAD--EDNRLHYEI--TGGNTRGRFSITSQNGRGLITVAQPLDFK 432 E++PPGT V+ + A DAD + ++ Y I G + G F I G IT D + Sbjct: 143 ENQPPGTGVLRVQAQDADLGVNGQVKYGIMHRDGVSSG-FHIDPD--AGYITTTVSFDRE 199 Query: 433 QERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYAPVFENAPYTAS 477 ++R + L+V+ATD + QI + D N+ P FEN+ Y ++ Sbjct: 200 RQREFTLSVTATDQADEPLIGICQITVLVADQNDNEPKFENSRYQST 246 Score = 42.7 bits (96), Expect = 0.14 Identities = 26/88 (29%), Positives = 36/88 (40%), Gaps = 4/88 (4%) Query: 1280 DFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSAP---CYNGAECSDLWDTYI 1336 D GCI + +D + DL S + AGC C S C C W ++ Sbjct: 1477 DQSGCIRNLVVDSQVYDLASPGESVDSWAGCRLTDGACVSGAGPSCGPRGSCVADWGSFS 1536 Query: 1337 CDCKEGHTGKDCADSTGPPWRFGGDGML 1364 C C G+ G C D+ P + FG +L Sbjct: 1537 CHCGPGYAGLKC-DAAVPEFSFGSGSLL 1563 Score = 41.1 bits (92), Expect = 0.43 Identities = 41/173 (23%), Positives = 73/173 (42%), Gaps = 9/173 (5%) Query: 227 IRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE 286 I A DGG+ RS++ +L + I +V++ P++ + +V EN IV ++A + Sbjct: 463 IVASDGGN--RSSSVELTVFITNVHNQPPQWDQPEYWVTVPENTVRDAKIVTIKA-TSPL 519 Query: 287 GVNAELTYTMTDKDYTG-NVDLPITIDPR----SGWVYTSGQLDRETQAKYQLLVTATDG 341 G + +TY + + N+ + + P S + + LD ET + L V + Sbjct: 520 G-DPRVTYDLEEGQVPETNMPVRFYVKPNRADGSASILVAENLDFETTGFFTLRVRVQNV 578 Query: 342 GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394 P ++ T F+ YE + E GT V ++A D D Sbjct: 579 ASVPLASFTTVYVNVTDVNDNVPFFLSSTYEATVPEGAQTGTSVAQVSAADLD 631 >UniRef50_Q5F4W0 Cluster: Putative uncharacterized protein; n=3; Caenorhabditis|Rep: Putative uncharacterized protein - Caenorhabditis elegans Length = 2779 Score = 256 bits (626), Expect = 8e-66 Identities = 229/834 (27%), Positives = 382/834 (45%), Gaps = 78/834 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I ++D ND++PVF +Y ASV S G+ ++T++ATD DIG+N+ + Y I+ +A Sbjct: 221 IEIIDANDNAPVFSRSRYTASVSANISIGSHLITVQATDADIGENSRISYDIKKTSA--- 277 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P ++ F I +SG + T ASL + + V+V A+D SP L Sbjct: 278 -PSNSN-------------FAIS-QSGVITTTASL--LPASTHDVIVVASDHGSP---SL 317 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SS+A + + ++ + P + + V + +N + I A + + Sbjct: 318 SSSAVVTITVLGSTLSSPPL-DIIWLVE-SNSAHLMENSTLGSIVARVSIAQQYRDTKLR 375 Query: 191 IIGGNTQMQFSIDSLSGDVSLV-KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 +IG + D + L+ LD E + L + G + L+ I D Sbjct: 376 LIGSSALCPQQTDQAHVYLLLLCGILDRETASEHHLKFLLEKDGQIIIEHPQ--LLTIGD 433 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 +NDNAP++++S Q +S N G S + A D D G N + Y++ D + + Sbjct: 434 INDNAPQWHSS--QIHISLNRTQGGSRT-LTAKDPDLGQNGWIRYSVLDTEL-------V 483 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 +ID +G ++ +D ++ + V A DGG P S F Sbjct: 484 SIDKETGRIFVPNTIDCNIGSEIKFRVRAEDGGSPALSTDLQVVADLLDTESKPPQFEKA 543 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 ++VE+ ED P GT +V + A ++ N R+ Y + + +T G + + + Sbjct: 544 LWQVEIPEDTPIGTCLVKVVANNSQCGNSKRIRYSLQNQDEH----LTVDTMSGTVCIQK 599 Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 DF++++ Y TV AT++ + T+++ I + D N+ P+F Y +V E Sbjct: 600 TFDFEKQKSYQTTVIATNANSETSTSLISIRLKDVNDNWPIFYPNEYHLTVREGPKPEEP 659 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 +LVVSA+D D G +++Y + SE S+ F INP TG + K L R + Sbjct: 660 LLVVSASDMDSGTFGEVSYHILSESSS---------FSINPVTGEVFAQKPLAR---GRF 707 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 L V+A+DGG S ++ ++ I+V+D + P F + Y ED L G ++ VGA Sbjct: 708 HLVVSAKDGGGQSSENSANIHITVIDKDTKTPQFSRSKYEIRTTEDILPGIAIGSVGAM- 766 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP- 666 ++ Y + D++ +F ID +G I + LD + HD + I P Sbjct: 767 ------SKVKYSIYSGDQDH-NFSIDEDTGKIYVTRYLDAD---VHDTVLLNIQATLPSG 816 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 +S+ V I IED ND+PP F S + I E+ + ++A D D+ N V YSI Sbjct: 817 ESNQTQVVIFIEDHNDNPPQFSSSLVEISIREDLKLHEPFYVVQASDKDKKKNGEVRYSI 876 Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEIL 783 +S ++ G +L T LDYE+ R Y+L ++A PP +++ + I Sbjct: 877 ISSHPGSSIEIDQFTG----QLSTGSLLDYEATR-NYKLRVKATDLGIPPRSSNMTLFIH 931 Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGN 835 V DVNDNAP + ++ P G+V A D D + ++ YRI +G+ Sbjct: 932 VLDVNDNAPEFEKSWYTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRITNGS 985 Score = 237 bits (581), Expect = 2e-60 Identities = 209/762 (27%), Positives = 335/762 (43%), Gaps = 67/762 (8%) Query: 138 VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQ 197 + I D NDN PQ+ +S++ + + A D D+G N IRY+++ +T+ Sbjct: 429 LTIGDINDNAPQWHSSQIHISLNRTQGGSRT-----LTAKDPDLGQNGWIRYSVL--DTE 481 Query: 198 MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF 257 + SID +G + + T+D + +RA+DGGSP+ S Q++ ++ D P+F Sbjct: 482 L-VSIDKETGRIFVPNTIDCNIGSEIKFRVRAEDGGSPALSTDLQVVADLLDTESKPPQF 540 Query: 258 YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317 +L+Q + E+ PIG +V+V A ++ G + + Y++ N D +T+D SG Sbjct: 541 EKALWQVEIPEDTPIGTCLVKVVANNSQCGNSKRIRYSLQ------NQDEHLTVDTMSGT 594 Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377 V D E Q YQ V AT+ ++T+ F P +Y + + E Sbjct: 595 VCIQKTFDFEKQKSYQTTVIATNANS--ETSTSLISIRLKDVNDNWPIFYPNEYHLTVRE 652 Query: 378 DEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435 P P++ ++A+D D + Y I ++ FSI G + +PL Sbjct: 653 GPKPEEPLLVVSASDMDSGTFGEVSYHILSESSS--FSINPVTGE--VFAQKPL---ARG 705 Query: 436 RYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 R+ L VSA D GG+S ++A + I + D + P F + Y ED G + Sbjct: 706 RFHLVVSAKDGGGQSSENSANIHITVIDKDTKTPQFSRSKYEIRTTEDILPGIAI----- 760 Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553 VG +++ YS+ S D F I+ TG I + LD + LL + A Sbjct: 761 --GSVGAMSKVKYSIYS-------GDQDHNFSIDEDTGKIYVTRYLDADVHDTVLLNIQA 811 Query: 554 RDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612 +PS S+ T V I + D NDN P F L +I ED + V A+D D Sbjct: 812 T---LPSGESNQTQVVIFIEDHNDNPPQFSSSLVEISIREDLKLHEPFYVVQASDKDKKK 868 Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672 NG + Y + S ID +G + T LD E+ + L+ A D G PP+SS + Sbjct: 869 NGEVRYSII-SSHPGSSIEIDQFTGQLSTGSLLDYEATRNYKLRVKATDLGIPPRSSNMT 927 Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD-- 730 + I + D+ND+ P FE T + ENSP T +G++ A D D N + Y I G Sbjct: 928 LFIHVLDVNDNAPEFEKSWYTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRITNGSEY 987 Query: 731 ---DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDV 787 D ++ T++ D+ E+++ VD+ + K PP + I V DV Sbjct: 988 FGIDEKLGNVYTKRSIDR-EVISHVDISIVAEDK--------GVPPRSSTASARISVLDV 1038 Query: 788 NDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNET 845 NDN P I G + A D D + + YR + + + ++ Sbjct: 1039 NDNPPSCLSITPIVVPAGSPLSTA-IGTIVAMDPDKGLNGSVLYR---AQLQSSLFVVKS 1094 Query: 846 TGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRL 886 G + L QLN + + + V V+D GV + + VR+ Sbjct: 1095 NGDVYLRRQLNASDERHQRLSVIVSDQGVPRKSVVCHVPVRI 1136 Score = 207 bits (505), Expect = 4e-51 Identities = 200/793 (25%), Positives = 337/793 (42%), Gaps = 63/793 (7%) Query: 91 RIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQF 150 ++D RSG + T A LD EK +++ ++ +++ D L V + D+NDN P F Sbjct: 70 KVDERSGEISTIAHLDYEKRSKFDIVAVKVEESGETIDIL-------VEVDDENDNAPSF 122 Query: 151 SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS------ 204 +++ + + E + + + + TD D R+ I+ GN F + S Sbjct: 123 ADQVVKLEISEFAQLGTSFALPTV--TDGDGPKFDVHRFVILQGNVNNVFKLASRKVNEQ 180 Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 L D+ + LD E Y L+I AQDGG P++ + I I D NDNAP F S + Sbjct: 181 LQADLVVNGQLDREFRDKYELLIEAQDGGKPAKIGQLRCSIEIIDANDNAPVFSRSRYTA 240 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 SVS N+ IG ++ VQA DAD G N+ ++Y + N + I+ +SG + T+ L Sbjct: 241 SVSANISIGSHLITVQATDADIGENSRISYDIKKTSAPSNSNFAIS---QSGVITTTASL 297 Query: 325 DRETQAKYQLLVTATDGGDPPRSATA----TXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380 + + ++V A+D G P S++A T ++ L E+ Sbjct: 298 --LPASTHDVIVVASDHGSPSLSSSAVVTITVLGSTLSSPPLDIIWLVESNSAHLMENST 355 Query: 381 PGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440 G+ V ++ D +L G++ T Q L+ + LD + + L Sbjct: 356 LGSIVARVSIAQQYRDTKLRLI---GSSALCPQQTDQAHVYLLLLCGILDRETASEHHLK 412 Query: 441 VSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 G + I D N+ AP + ++ S+ T ++A D D+G Sbjct: 413 FLLEKDGQIIIEHPQLLTIGDINDNAPQWHSSQIHISLNRTQGGSRT---LTAKDPDLGQ 469 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560 N I YS+ + E V+ I+ +TG I +D S V A DGG P+ Sbjct: 470 NGWIRYSV---LDTELVS-------IDKETGRIFVPNTIDCNIGSEIKFRVRAEDGGSPA 519 Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620 LS V ++D P F++ L+ I ED +GT + +V A ++ G + RI Y L Sbjct: 520 LSTDLQVVADLLDTESKPPQFEKALWQVEIPEDTPIGTCLVKVVANNSQCGNSKRIRYSL 579 Query: 621 DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680 +D +D SG + K D E ++ +A + + ++ST ++ I+++D+ Sbjct: 580 QNQDEH---LTVDTMSGTVCIQKTFDFEKQKSYQTTVIATNANS--ETSTSLISIRLKDV 634 Query: 681 NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR 740 ND+ P+F + + E + + A D D G V Y I +S+SFS+ Sbjct: 635 NDNWPIFYPNEYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHIL--SESSSFSINPV 692 Query: 741 QGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDF 797 G E+ L R ++ LV+ A N + I V D + P Sbjct: 693 TG----EVFAQKPL----ARGRFHLVVSAKDGGGQSSENSANIHITVIDKDTKTPQFSRS 744 Query: 798 QIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNT 857 + +D P G V A K++Y I SG+ + ++E TG + ++ L+ Sbjct: 745 KYEIRTTEDILPGIAIGSVGA-----MSKVKYSIYSGDQDHNFSIDEDTGKIYVTRYLDA 799 Query: 858 NVPKLATMEVSVT 870 +V + + T Sbjct: 800 DVHDTVLLNIQAT 812 Score = 192 bits (468), Expect = 1e-46 Identities = 182/686 (26%), Positives = 298/686 (43%), Gaps = 57/686 (8%) Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L PE A + F +D G + T LDRE + RY++ V T + R Sbjct: 1854 LQPELAGLTYSIVEGNIDSAFSVDSE-GVIRTNLELDREILERYSLKVIGTGSGQQIGTR 1912 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + + VN + NDN P F + V E++ V +A + A D D A +RY Sbjct: 1913 VD----VRVNNL--NDNVPSFP-MSKPRRVPENLRV--GSYVATVGAKDVDNLA--PLRY 1961 Query: 190 AIIG---GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 ++ G T F+ID +G + L LD+E + + L I+A DG S T L I Sbjct: 1962 FLVSDSSGQTPTHFNIDQFTGTIHLTAPLDFEVLPEHTLTIKATDG---SFDTFTNLTIF 2018 Query: 247 IRDVNDNAPRFYTSLFQESVSE-NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 + D+NDNAP F L+Q +VS G +++A+D D LTY++ G+ Sbjct: 2019 VSDINDNAPTFSKPLYQTTVSPATFSPGQPFAKIEAHDLD--ARGALTYSLGQ----GSS 2072 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX- 364 + + P SG ++ ++ +Y + VTATD G P S + Sbjct: 2073 SI-FRVAPESGALFM--KVLPPAGERYLVTVTATDNGVPSFSTSVPVSVIIGEAEPTDKP 2129 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLIT 424 F ++ E+ E+ G + L+ +E HY I FSI G + Sbjct: 2130 GFEKAEFRFEVMENSKIGLQIGNLSG---EESREFHYRIQDPEASKIFSIDKF---GRLF 2183 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDA 482 VA P+D +Q + V + S + ++ D N+ PVF + Y S+ + Sbjct: 2184 VAGPIDREQRATHEFQVEIDNEMMTSQKVQCKCHVIVLDENDNLPVFTSVAYYLSLKDSM 2243 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL---- 538 G + + A+D D G N +++Y + S V +NP TG+I N+ Sbjct: 2244 AHGQKIGQIMASDQDSGENGRVSYRILSGNDLNIVT-------LNPDTGSIQLNEWNDAQ 2296 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV--DVNDNEPVFKQQLYTANIMEDALV 596 LD + + + V ARD G P+ + V++S+ + + P F +Y +++ED V Sbjct: 2297 LDEFPNATWQILVEARDHGHPARAAVGKVQVSLKMSSWSGSAPFFVLPVYEVHVLEDTSV 2356 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 GT + ++ A++ N + Y L +G ID +G + LD ES + Sbjct: 2357 GTVLQKIRASNRLGMRNDGLLYSLK---EHQGKLGIDVKTGELTLKTHLDWESEPIISMY 2413 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 DG +S+ V + I +E +++ PVF T I ++P G ++G+++A D D Sbjct: 2414 LSVSDGNG--RSAVVPLKIVVEPVDEFAPVFTKSSYTLQIPISTPAGESVGQMQAIDEDG 2471 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQG 742 G + VV YSI D ++ +E G Sbjct: 2472 GVHGVVKYSI--SDRQSTVKIEEHTG 2495 Score = 175 bits (425), Expect = 2e-41 Identities = 169/582 (29%), Positives = 258/582 (44%), Gaps = 69/582 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D ND+ P+F +Y +VREG +L + A+D D G EV Y I L Sbjct: 629 IRLKDVNDNWPIFYPNEYHLTVREGPKPEEPLLVVSASDMDSGTFGEVSYHI-------L 681 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + + F I+ +G + + L R R+ ++V A D S+ Sbjct: 682 SESSS--------------FSINPVTGEVFAQKPLAR---GRFHLVVSAKDGGGQSSE-- 722 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 ++A IH+ +ID + PQFS Y + EDI P IA VGA S ++Y+ Sbjct: 723 -NSANIHITVIDKDTKTPQFSRSKYEIRTTEDIL----PGIA-----IGSVGAMSKVKYS 772 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS-RSNTTQLLINIRD 249 I G+ FSID +G + + + LD + + L I+A PS SN TQ++I I D Sbjct: 773 IYSGDQDHNFSIDEDTGKIYVTRYLDADVHDTVLLNIQAT---LPSGESNQTQVVIFIED 829 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 NDN P+F +SL + S+ E++ + VQA D D+ N E+ Y++ + G+ I Sbjct: 830 HNDNPPQFSSSLVEISIREDLKLHEPFYVVQASDKDKKKNGEVRYSII-SSHPGS---SI 885 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 ID +G + T LD E Y+L V ATD G PPRS+ T F Sbjct: 886 EIDQFTGQLSTGSLLDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKS 945 Query: 370 QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 Y +E+ E+ PP T V + A D D E+ ++ Y IT G+ F I + G + + Sbjct: 946 WYTMEVLENSPPKTIVGKVVARDKDSLENGQIVYRITNGSE--YFGIDEKLGN--VYTKR 1001 Query: 428 PLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAP-VFENAPYTASVFEDAPI 484 +D + +++ A D G RS TA +I++ D N+ P P V +P+ Sbjct: 1002 SIDREVISHVDISIVAEDKGVPPRSSTASARISVLDVNDNPPSCLSITPIV--VPAGSPL 1059 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 T + + A D D G+N + Y + S FV+ G + + L+ Sbjct: 1060 STAIGTIVAMDPDKGLNGSVLYRAQLQSS---------LFVVK-SNGDVYLRRQLNASDE 1109 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISV----VDVNDNEPVFK 582 L+V D GVP S V + + D+ EP K Sbjct: 1110 RHQRLSVIVSDQGVPRKSVVCHVPVRISKGSADIQIQEPFQK 1151 Score = 172 bits (419), Expect = 1e-40 Identities = 180/691 (26%), Positives = 296/691 (42%), Gaps = 63/691 (9%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F I+ +G++ LDRE + +++ TD S + + T+ V + D NDN PQ Sbjct: 1673 FSINSTTGSISV-LPLDREASQEHLLIIILTDGGSR-----NDSCTVRVTVADQNDNKPQ 1726 Query: 150 FSEKTYT-VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 T + + + E V D V+ + +A+D D+G N + ++ ++ + +GD Sbjct: 1727 LDASTPSELEIAESSRVGD--VLHRFRASDMDIGQNGKFSFELLEDSSG-SLDLVPETGD 1783 Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP---RFYTSLFQES 265 + L + ++S+++ +R D G P L I+ R+ A F + + Sbjct: 1784 LVLRRL---SSLQSWKIKLRVVDHGVPGLYVEKNLEISNRNPQTEAKAPLEFLKQTYLST 1840 Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325 + E +P G I ++Q A LTY++ + GN+D ++D G + T+ +LD Sbjct: 1841 IDEGLPRGQFIAKLQPELAG------LTYSIVE----GNIDSAFSVDSE-GVIRTNLELD 1889 Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 RE +Y L V T G T P + E+ G+ V Sbjct: 1890 REILERYSLKVIGTGSGQQ----IGTRVDVRVNNLNDNVPSFPMSKPRRVPENLRVGSYV 1945 Query: 386 VTLTATDADEDNRLHYEI---TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 T+ A D D L Y + + G T F+I G I + PLDF+ + LT+ Sbjct: 1946 ATVGAKDVDNLAPLRYFLVSDSSGQTPTHFNIDQFTGT--IHLTAPLDFEVLPEHTLTIK 2003 Query: 443 ATDSGGRSDT-AMVQINITDANNYAPVFENAPY--TASVFEDAPIGTTVLVVSATDSDVG 499 ATD G DT + I ++D N+ AP F Y T S +P G + A D D Sbjct: 2004 ATD--GSFDTFTNLTIFVSDINDNAPTFSKPLYQTTVSPATFSP-GQPFAKIEAHDLDA- 2059 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 +TYSL S+ F + P++GA+ L YL+TVTA D GVP Sbjct: 2060 -RGALTYSLGQGSSSI--------FRVAPESGALFMKVL--PPAGERYLVTVTATDNGVP 2108 Query: 560 SLSDTTDVEISVVDVNDNE-PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618 S S + V + + + + P F++ + +ME++ +G + + ++ HY Sbjct: 2109 SFSTSVPVSVIIGEAEPTDKPGFEKAEFRFEVMENSKIGLQIGNLSGEESR-----EFHY 2163 Query: 619 ELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678 + + + F ID G + +DRE ATH+ + + Q H+ + Sbjct: 2164 RIQDPEASK-IFSIDKF-GRLFVAGPIDREQRATHEFQVEIDNEMMTSQKVQCKCHVIVL 2221 Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738 D ND+ PVF S + ++ G IG+I A D D G N V Y I G+D N +L Sbjct: 2222 DENDNLPVFTSVAYYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRILSGNDLNIVTLN 2281 Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 GS + LD E P +++++ A Sbjct: 2282 PDTGSIQLNEWNDAQLD-EFPNATWQILVEA 2311 Score = 168 bits (409), Expect = 2e-39 Identities = 185/748 (24%), Positives = 318/748 (42%), Gaps = 69/748 (9%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F ID +G + LD + TVL+ QA+ S + T + + I D NDN PQ Sbjct: 782 FSIDEDTGKIYVTRYLDAD--VHDTVLLNI--QATLPSGESNQTQVV-IFIEDHNDNPPQ 836 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209 FS +S+ ED+ + + + ++A+D D N +RY+II + ID +G + Sbjct: 837 FSSSLVEISIREDLKLHEPFYV--VQASDKDKKKNGEVRYSIISSHPGSSIEIDQFTGQL 894 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269 S LDYE R+Y+L ++A D G P RS+ L I++ DVNDNAP F S + V EN Sbjct: 895 STGSLLDYEATRNYKLRVKATDLGIPPRSSNMTLFIHVLDVNDNAPEFEKSWYTMEVLEN 954 Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTD-KDYTGNVDLPITIDPRSGWVYTSGQLDRET 328 P + +V A D D N ++ Y +T+ +Y G ID + G VYT +DRE Sbjct: 955 SPPKTIVGKVVARDKDSLENGQIVYRITNGSEYFG-------IDEKLGNVYTKRSIDREV 1007 Query: 329 QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388 + + + A D G PPRS+TA+ + + + P T + T+ Sbjct: 1008 ISHVDISIVAEDKGVPPRSSTASARISVLDVNDNPPSCL-SITPIVVPAGSPLSTAIGTI 1066 Query: 389 TATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG 448 A D D+ L+ + + + S+ G + + + L+ ER L+V +D G Sbjct: 1067 VAMDPDKG--LNGSVL-YRAQLQSSLFVVKSNGDVYLRRQLNASDERHQRLSVIVSDQGV 1123 Query: 449 RSDTAMVQINITDANNYAPVFENAPYT--ASVFEDAPIGTTVLVVSATDSDVGINAQITY 506 + + + + + A + P+ + + P G + ++AT G+++ + Sbjct: 1124 PRKSVVCHVPVRISKGSADIQIQEPFQKYIEIPKSCPTGCRLTTLNAT----GVSSWLIQ 1179 Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566 SSEISN F+I+ + R Y L + D + Sbjct: 1180 --SSEISNHFAIREGVLFMISHP---------IHRPP---YSLVIVLSD------KNDRQ 1219 Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE 626 I + + E K++ T I + +GT + ++G AD G Y E Sbjct: 1220 KSIQLRVLASGEAANKEE--TIRISDSNSIGTKIGRLGEKSAD----GSFFYRF--SSEE 1271 Query: 627 EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI-VHIKIEDINDSPP 685 +D G++ L R TH+ T S+ + V ++I P Sbjct: 1272 SCPLELDQTGGLLYLADGLRRGD--THNFSCFFEKFNTTDGSAEEMRVDLEISRTKSDKP 1329 Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745 F++ L I E++P G+ I + A D+ + + S + ++FS++ G Sbjct: 1330 RFDTGHLRVNIREDTPTGSIITTVNATVSDDSASPI---SYRFPLLIDNFSIDQFTGD-- 1384 Query: 746 AELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP--VMKDFQIIFNN 803 +T++D + Y L++ A + + V + V DVND+ P V + ++ ++ Sbjct: 1385 ---ITLIDTLHWHVTPTYNLIVEAFTSGPGTTLLVTVNVDDVNDHTPFIVSQPTVLLPSS 1441 Query: 804 YKDCFPVGPFGRVPAYDADVTDKLQYRI 831 Y+ G RV A D D +++Y + Sbjct: 1442 YR---KGGMVHRVVAIDLDKDPEIRYSL 1466 Score = 167 bits (406), Expect = 4e-39 Identities = 207/771 (26%), Positives = 333/771 (43%), Gaps = 77/771 (9%) Query: 95 RSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKT 154 +S ++ +++ R+T++ + D+ ST IHV + P+ S + Sbjct: 1584 KSSKIVQKSASVATGTQRFTIVAQKDDELD------YSTLKIHVEPVFTEP--PKISSTS 1635 Query: 155 Y-TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVK 213 V+++E++ + D +I AT + S R+ GN +FSI+S +G +S++ Sbjct: 1636 CGVVTIEENVGIED---FKRILATG--MTEESRFRFQ---GNAP-KFSINSTTGSISVLP 1686 Query: 214 TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE-SVSENVPI 272 LD E + + L+I DGGS R+++ + + + D NDN P+ S E ++E+ + Sbjct: 1687 -LDREASQEHLLIIILTDGGS--RNDSCTVRVTVADQNDNKPQLDASTPSELEIAESSRV 1743 Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332 G + R +A D D G N + ++ + + D +G++DL P +G + +L K Sbjct: 1744 GDVLHRFRASDMDIGQNGKFSFELLE-DSSGSLDLV----PETGDLVLR-RLSSLQSWKI 1797 Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXX---FMPGQYEVELAEDEPPGTPVVTLT 389 +L V D G P F+ Y + E P G + L Sbjct: 1798 KLRVV--DHGVPGLYVEKNLEISNRNPQTEAKAPLEFLKQTYLSTIDEGLPRGQFIAKLQ 1855 Query: 390 ATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR 449 A L Y I GN FS+ S+ G+I LD + RY L V T SG + Sbjct: 1856 PELAG----LTYSIVEGNIDSAFSVDSE---GVIRTNLELDREILERYSLKVIGTGSGQQ 1908 Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509 T V + + + N+ P F + V E+ +G+ V V A D D A + Y L Sbjct: 1909 IGTR-VDVRVNNLNDNVPSFPMSK-PRRVPENLRVGSYVATVGAKDVDN--LAPLRYFLV 1964 Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569 S+ S + H F I+ TG I LD E + + LT+ A DG S T++ I Sbjct: 1965 SDSSGQTPTH----FNIDQFTGTIHLTAPLDFEVLPEHTLTIKATDG---SFDTFTNLTI 2017 Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALV-GTSVSQVGATDADVGLNGRIHYELDPKDREEG 628 V D+NDN P F + LY + G +++ A D D G + Y L Sbjct: 2018 FVSDINDNAPTFSKPLYQTTVSPATFSPGQPFAKIEAHDLDA--RGALTYSLG--QGSSS 2073 Query: 629 SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP-PVF 687 F + P SG + K L + + A D G P S++V V + I + + P F Sbjct: 2074 IFRVAPESGALFM-KVLPPAG-ERYLVTVTATDNGVPSFSTSVPVSVIIGEAEPTDKPGF 2131 Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747 E F + ENS IG IG + + E HY I+ + S FS++ Sbjct: 2132 EKAEFRFEVMENSKIGLQIGNLSGEESRE-----FHYRIQDPEASKIFSIDKF-----GR 2181 Query: 748 LVTMVDLDYESPRKKYELVIRAASPPLWND---VRVEILVTDVNDNAPVMKDFQIIFNNY 804 L +D E R +E + + + + + ++V D NDN PV + + Sbjct: 2182 LFVAGPIDREQ-RATHEFQVEIDNEMMTSQKVQCKCHVIVLDENDNLPVFTSVAY-YLSL 2239 Query: 805 KDCFPVGP-FGRVPAYDADVTD--KLQYRILSGNNANLILLNETTGSMTLS 852 KD G G++ A D D + ++ YRILSGN+ N++ LN TGS+ L+ Sbjct: 2240 KDSMAHGQKIGQIMASDQDSGENGRVSYRILSGNDLNIVTLNPDTGSIQLN 2290 Score = 142 bits (345), Expect = 9e-32 Identities = 166/683 (24%), Positives = 295/683 (43%), Gaps = 54/683 (7%) Query: 184 NSAIRYAIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLV-IRAQDGGSPSRSNT 240 ++A +Y ++ + Q +D SG++S + LDYE+ + +V ++ ++ G T Sbjct: 51 SAAPKYFVVFPDEQTSKFLKVDERSGEISTIAHLDYEKRSKFDIVAVKVEESG-----ET 105 Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 +L+ + D NDNAP F + + +SE +G S D D G ++ + + Sbjct: 106 IDILVEVDDENDNAPSFADQVVKLEISEFAQLGTSFALPTVTDGD-GPKFDVHRFVILQG 164 Query: 301 YTGNVDLPIT---IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357 NV + + + +GQLDRE + KY+LL+ A DGG P + Sbjct: 165 NVNNVFKLASRKVNEQLQADLVVNGQLDREFRDKYELLIEAQDGGKPAKIGQLRCSIEII 224 Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEI--TGGNTRGRFS 413 F +Y ++ + G+ ++T+ ATDAD E++R+ Y+I T + F+ Sbjct: 225 DANDNAPVFSRSRYTASVSANISIGSHLITVQATDADIGENSRISYDIKKTSAPSNSNFA 284 Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAP----VF 469 I+ G+IT L ++ S S S +A+V I + + +P ++ Sbjct: 285 ISQS---GVITTTASLLPASTHDVIVVASDHGSPSLSSSAVVTITVLGSTLSSPPLDIIW 341 Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 +A + E++ +G+ V VS ++ S S DQ V Sbjct: 342 LVESNSAHLMENSTLGSIVARVSIAQQYRDTKLRLIGS-----SALCPQQTDQAHVY--- 393 Query: 530 TGAITTNKLLDRETMS-GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588 + +LDRET S +L + +DG + + + + +++ D+NDN P + Sbjct: 394 --LLLLCGILDRETASEHHLKFLLEKDGQI--IIEHPQL-LTIGDINDNAPQWHSS--QI 446 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648 +I + G S + A D D+G NG I Y + D E S ID +G I +D Sbjct: 447 HISLNRTQGGS-RTLTAKDPDLGQNGWIRYSV--LDTELVS--IDKETGRIFVPNTIDCN 501 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 + + A DGG+P S+ + V + D PP FE I E++PIGT + + Sbjct: 502 IGSEIKFRVRAEDGGSPALSTDLQVVADLLDTESKPPQFEKALWQVEIPEDTPIGTCLVK 561 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768 + A++ G + + YS++ D+ +++T G+ + D+E + VI Sbjct: 562 VVANNSQCGNSKRIRYSLQNQDE--HLTVDTMSGT----VCIQKTFDFEKQKSYQTTVIA 615 Query: 769 AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDK 826 + + + I + DVNDN P+ + + P P V A D D + Sbjct: 616 TNANSETSTSLISIRLKDVNDNWPIFYPNEYHLTVREGPKPEEPLLVVSASDMDSGTFGE 675 Query: 827 LQYRILSGNNANLILLNETTGSM 849 + Y ILS +++ +N TG + Sbjct: 676 VSYHILSESSS--FSINPVTGEV 696 Score = 142 bits (343), Expect = 2e-31 Identities = 155/620 (25%), Positives = 264/620 (42%), Gaps = 54/620 (8%) Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 +F ++TY ++DE + IAK++ A + Y+I+ GN FS+DS G Sbjct: 1831 EFLKQTYLSTIDEGLP--RGQFIAKLQPELA------GLTYSIVEGNIDSAFSVDS-EGV 1881 Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268 + LD E + Y L + G + T++ + + ++NDN P F S V E Sbjct: 1882 IRTNLELDREILERYSLKVIGTGSG---QQIGTRVDVRVNNLNDNVPSFPMSK-PRRVPE 1937 Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328 N+ +G + V A D D A L Y + D +G ID +G ++ + LD E Sbjct: 1938 NLRVGSYVATVGAKDVDN--LAPLRYFLVS-DSSGQTPTHFNIDQFTGTIHLTAPLDFEV 1994 Query: 329 QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE-PPGTPVVT 387 ++ L + ATDG F Y+ ++ PG P Sbjct: 1995 LPEHTLTIKATDGSF---DTFTNLTIFVSDINDNAPTFSKPLYQTTVSPATFSPGQPFAK 2051 Query: 388 LTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447 + A D D L Y + G++ F + ++G + V P RY++TV+ATD+G Sbjct: 2052 IEAHDLDARGALTYSLGQGSS-SIFRVAPESGALFMKVLPPAG----ERYLVTVTATDNG 2106 Query: 448 GRSDTAMVQINITDAN---NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504 S + V +++ P FE A + V E++ IG + +S +S + +I Sbjct: 2107 VPSFSTSVPVSVIIGEAEPTDKPGFEKAEFRFEVMENSKIGLQIGNLSGEESRE-FHYRI 2165 Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT 564 +S+I + + + FV P +DRE + + V + + S Sbjct: 2166 QDPEASKIFS--IDKFGRLFVAGP----------IDREQRATHEFQVEIDNEMMTSQKVQ 2213 Query: 565 TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624 + V+D NDN PVF Y ++ + G + Q+ A+D D G NGR+ Y + Sbjct: 2214 CKCHVIVLDENDNLPVFTSVAYYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRI-LSG 2272 Query: 625 REEGSFVIDPASGVIRTNK----ALDRESVATHDLKAVAIDGGTPPQSST--VIVHIKIE 678 + ++P +G I+ N+ LD AT + A D G P +++ V V +K+ Sbjct: 2273 NDLNIVTLNPDTGSIQLNEWNDAQLDEFPNATWQILVEARDHGHPARAAVGKVQVSLKMS 2332 Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738 + S P F ++ E++ +GT + +IRA + N + YS+K + ++ Sbjct: 2333 SWSGSAPFFVLPVYEVHVLEDTSVGTVLQKIRASNRLGMRNDGLLYSLK--EHQGKLGID 2390 Query: 739 TRQGSDKAELVTMVDLDYES 758 + G EL LD+ES Sbjct: 2391 VKTG----ELTLKTHLDWES 2406 Score = 124 bits (298), Expect = 5e-26 Identities = 123/500 (24%), Positives = 209/500 (41%), Gaps = 38/500 (7%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +FR+ SGAL + + RY V V ATD P S S ++ + + D P Sbjct: 2074 IFRVAPESGALFMKVLPPAGE--RYLVTVTATDNGVP-SFSTSVPVSVIIGEAEPTDK-P 2129 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 F + + V E+ + I + ++ Y I FSID G Sbjct: 2130 GFEKAEFRFEVMENSKI--GLQIGNLSGEES-----REFHYRIQDPEASKIFSIDKF-GR 2181 Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268 + + +D EQ ++ + + S+ + + + D NDN P F + + S+ + Sbjct: 2182 LFVAGPIDREQRATHEFQVEIDNEMMTSQKVQCKCHVIVLDENDNLPVFTSVAYYLSLKD 2241 Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV----YTSGQL 324 ++ G I ++ A D D G N ++Y + +GN +T++P +G + + QL Sbjct: 2242 SMAHGQKIGQIMASDQDSGENGRVSYRIL----SGNDLNIVTLNPDTGSIQLNEWNDAQL 2297 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX--FMPGQYEVELAEDEPPG 382 D A +Q+LV A D G P R+A F+ YEV + ED G Sbjct: 2298 DEFPNATWQILVEARDHGHPARAAVGKVQVSLKMSSWSGSAPFFVLPVYEVHVLEDTSVG 2357 Query: 383 TPVVTLTATD--ADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440 T + + A++ ++ L Y + +G+ I + G +T+ LD++ E + Sbjct: 2358 TVLQKIRASNRLGMRNDGLLYSLK--EHQGKLGIDVKTGE--LTLKTHLDWESEPIISMY 2413 Query: 441 VSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 +S +D GRS ++I + + +APVF + YT + P G +V + A D D G+ Sbjct: 2414 LSVSDGNGRSAVVPLKIVVEPVDEFAPVFTKSSYTLQIPISTPAGESVGQMQAIDEDGGV 2473 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK-LLDRETMSGYLLTVTARDGGVP 559 + + YS+S S + H TG I K L+ R ++ +TV A Sbjct: 2474 HGVVKYSISDRQSTVKIEEH---------TGIIRLQKPLVSRRNLTIEQITVVAYSSPTK 2524 Query: 560 SLSDTTDVEISVVDVNDNEP 579 T +EI DV + P Sbjct: 2525 QSKTTVYLEIGPFDVQPSLP 2544 Score = 88.2 bits (209), Expect = 3e-15 Identities = 79/297 (26%), Positives = 131/297 (44%), Gaps = 28/297 (9%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI---ELVTADT 69 VLD ND+ PVF Y S+++ + G + + A+DQD G+N V Y I + T Sbjct: 2220 VLDENDNLPVFTSVAYYLSLKDSMAHGQKIGQIMASDQDSGENGRVSYRILSGNDLNIVT 2279 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 LNP+ A LD A + +LV+A D P Sbjct: 2280 LNPDTGSIQLNE------------------WNDAQLDEFPNATWQILVEARDHGHPARAA 2321 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + + + + + + P F Y V V ED SV V+ KI+A++ N + Y Sbjct: 2322 VGK-VQVSLKMSSWSGSAPFFVLPVYEVHVLEDTSV--GTVLQKIRASNRLGMRNDGLLY 2378 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 ++ Q + ID +G+++L LD+E + + DG RS L I + Sbjct: 2379 SL--KEHQGKLGIDVKTGELTLKTHLDWESEPIISMYLSVSDGN--GRSAVVPLKIVVEP 2434 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 V++ AP F S + + + P G S+ ++QA D D GV+ + Y+++D+ T ++ Sbjct: 2435 VDEFAPVFTKSSYTLQIPISTPAGESVGQMQAIDEDGGVHGVVKYSISDRQSTVKIE 2491 Score = 87.8 bits (208), Expect = 4e-15 Identities = 105/406 (25%), Positives = 182/406 (44%), Gaps = 33/406 (8%) Query: 478 VFEDAP-IGTTVLVVSATDSDVGIN--AQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 VF + P I +T V + +VGI +I + +E S + +F IN TG+I+ Sbjct: 1624 VFTEPPKISSTSCGVVTIEENVGIEDFKRILATGMTEESRFRFQGNAPKFSINSTTGSIS 1683 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA-NIMED 593 L DRE +LL + DGG S +D+ V ++V D NDN+P + I E Sbjct: 1684 VLPL-DREASQEHLLIIILTDGG--SRNDSCTVRVTVADQNDNKPQLDASTPSELEIAES 1740 Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653 + VG + + A+D D+G NG+ +EL + GS + P +G + + S+ + Sbjct: 1741 SRVGDVLHRFRASDMDIGQNGKFSFEL--LEDSSGSLDLVPETGDLVLRRL---SSLQSW 1795 Query: 654 DLKAVAIDGGTPP---QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710 +K +D G P + + I + + +P F I E P G I +++ Sbjct: 1796 KIKLRVVDHGVPGLYVEKNLEISNRNPQTEAKAPLEFLKQTYLSTIDEGLPRGQFIAKLQ 1855 Query: 711 AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770 P+ A + YSI G+ ++FS+++ + + T ++LD E ++Y L + Sbjct: 1856 ---PEL---AGLTYSIVEGNIDSAFSVDS-----EGVIRTNLELDREI-LERYSLKVIGT 1903 Query: 771 SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDKLQY 829 RV++ V ++NDN P + + VG + V A D D L+Y Sbjct: 1904 GSGQQIGTRVDVRVNNLNDNVPSFPMSKP--RRVPENLRVGSYVATVGAKDVDNLAPLRY 1961 Query: 830 RILS---GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 ++S G +++ TG++ L+ L+ V T+ + TDG Sbjct: 1962 FLVSDSSGQTPTHFNIDQFTGTIHLTAPLDFEVLPEHTLTIKATDG 2007 Score = 81.4 bits (192), Expect = 3e-13 Identities = 66/221 (29%), Positives = 104/221 (47%), Gaps = 14/221 (6%) Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638 P F Q L + E A +GT + + + ++ + P ++ +D SG Sbjct: 20 PTFCQCLTKFTVPESAQIGTRIGWISGKREESAAPK--YFVVFPDEQTSKFLKVDERSGE 77 Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698 I T LD E + D+ AV ++ T+ + ++++D ND+ P F + ISE Sbjct: 78 ISTIAHLDYEKRSKFDIVAVKVE----ESGETIDILVEVDDENDNAPSFADQVVKLEISE 133 Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVH-YSIKGGDDSNSFSLETRQGSD--KAELVTMVDLD 755 + +GT+ D D GP VH + I G+ +N F L +R+ ++ +A+LV LD Sbjct: 134 FAQLGTSFALPTVTDGD-GPKFDVHRFVILQGNVNNVFKLASRKVNEQLQADLVVNGQLD 192 Query: 756 YESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPV 793 E R KYEL+I A P +R I + D NDNAPV Sbjct: 193 REF-RDKYELLIEAQDGGKPAKIGQLRCSIEIIDANDNAPV 232 Score = 54.8 bits (126), Expect = 3e-05 Identities = 50/196 (25%), Positives = 90/196 (45%), Gaps = 18/196 (9%) Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS- 185 +D + + + I + P+F V++ ED +I + AT +D A+ Sbjct: 1308 TDGSAEEMRVDLEISRTKSDKPRFDTGHLRVNIREDTPT--GSIITTVNATVSDDSASPI 1365 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 + R+ ++ N FSID +GD++L+ TL + +Y L++ A G T + + Sbjct: 1366 SYRFPLLIDN----FSIDQFTGDITLIDTLHWHVTPTYNLIVEAFTSGP---GTTLLVTV 1418 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 N+ DVND+ P F S + + G + RV A D D+ + E+ Y++ Y G+ Sbjct: 1419 NVDDVNDHTP-FIVSQPTVLLPSSYRKGGMVHRVVAIDLDK--DPEIRYSL---KYAGSE 1472 Query: 306 DLP--ITIDPRSGWVY 319 ID +SG ++ Sbjct: 1473 VAKEFFKIDEKSGEIF 1488 Score = 44.4 bits (100), Expect = 0.046 Identities = 53/192 (27%), Positives = 75/192 (39%), Gaps = 14/192 (7%) Query: 448 GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507 G ++ V + I+ + P F+ ++ ED P G+ + V+AT SD + I+Y Sbjct: 1310 GSAEEMRVDLEISRTKSDKPRFDTGHLRVNIREDTPTGSIITTVNATVSDDSA-SPISYR 1368 Query: 508 LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567 I N F I+ TG IT L Y L V A G T V Sbjct: 1369 FPLLIDN---------FSIDQFTGDITLIDTLHWHVTPTYNLIVEAFTSGP---GTTLLV 1416 Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627 ++V DVND+ P Q T + G V +V A D D R + + + Sbjct: 1417 TVNVDDVNDHTPFIVSQ-PTVLLPSSYRKGGMVHRVVAIDLDKDPEIRYSLKYAGSEVAK 1475 Query: 628 GSFVIDPASGVI 639 F ID SG I Sbjct: 1476 EFFKIDEKSGEI 1487 Score = 44.4 bits (100), Expect = 0.046 Identities = 107/492 (21%), Positives = 186/492 (37%), Gaps = 42/492 (8%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQNGRGLIT 424 F G V + ED P G+ + T+ AT +D+ + + Y FSI G IT Sbjct: 1331 FDTGHLRVNIREDTPTGSIITTVNATVSDDSASPISYRFP--LLIDNFSIDQFTGD--IT 1386 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 + L + Y L V A SG + T +V +N+ D N++ P + P T + Sbjct: 1387 LIDTLHWHVTPTYNLIVEAFTSGPGT-TLLVTVNVDDVNDHTPFIVSQP-TVLLPSSYRK 1444 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 G V V A D D + +I YSL S A + F I+ ++G I Sbjct: 1445 GGMVHRVVAIDLDK--DPEIRYSLKYAGSEVA----KEFFKIDEKSGEIFV-------VE 1491 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 S L+ + G+P ++ + D + V L +N Sbjct: 1492 SSSALSTSFGGAGLPETLTIRATDLQDLTKFDEQKVL---LKASNASRSTWHFFDEQHKD 1548 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE-SVATHDLK-AVAIDG 662 T G +L ++ + + ++++K + + SVAT + + Sbjct: 1549 VTILSTSPQGSQILQLKFQEGVDLQLIPSSPHFELKSSKIVQKSASVATGTQRFTIVAQK 1608 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 ST+ +H++ + P + + C I EN I I A G Sbjct: 1609 DDELDYSTLKIHVE-PVFTEPPKISSTSCGVVTIEENVGI-EDFKRILA----TGMTEES 1662 Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEI 782 + +G ++ FS+ + GS ++++ LD E+ ++ ++I + V + Sbjct: 1663 RFRFQG--NAPKFSINSTTGS-----ISVLPLDREASQEHLLIIILTDGGSRNDSCTVRV 1715 Query: 783 LVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADV--TDKLQYRILSGNNANL 839 V D NDN P + + VG R A D D+ K + +L ++ +L Sbjct: 1716 TVADQNDNKPQLDASTPSELEIAESSRVGDVLHRFRASDMDIGQNGKFSFELLEDSSGSL 1775 Query: 840 ILLNETTGSMTL 851 L+ E TG + L Sbjct: 1776 DLVPE-TGDLVL 1786 >UniRef50_UPI0000DB7905 Cluster: PREDICTED: similar to Cad99C CG31009-PA, partial; n=3; Endopterygota|Rep: PREDICTED: similar to Cad99C CG31009-PA, partial - Apis mellifera Length = 1556 Score = 255 bits (625), Expect = 1e-65 Identities = 251/898 (27%), Positives = 385/898 (42%), Gaps = 73/898 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVL-TLKATDQDIGKNAEVEYTIELVTADT 69 + V D ND++P F YE +V E G+T+ + A D D G N VEY+I Sbjct: 99 VRVSDINDNAPKFINTPYETTVPELTPVGSTIFKNVVAVDADAGVNGIVEYSIAPGDGTG 158 Query: 70 LNPEDAXXXXXXXXXXVQDVFRID-GRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 + D F I+ G + +LD E+ RY V + A+D+A VS+ Sbjct: 159 IGNNDGVGRNRITTADGYGYFSINLPHQGQVTVNRTLDFERTQRYLVTILASDRARNVSE 218 Query: 129 RLSSTATIHVNIIDDNDNYPQF------------SEKTYTVSVDEDI-SVTDNPVIAKIK 175 R +ST T+ VNI DD+D P F Y+ SV + S N KI+ Sbjct: 219 RFTSTTTLTVNIRDDDDQDPSFIYQGCMLLDGACINPEYSASVSSGVLSGILNISPEKIQ 278 Query: 176 ATDADVGANSAIRYAIIGGNT---QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232 A D D N+ I Y+ + GN + F I+ +G V +K +D + + ++I+A + Sbjct: 279 AVDMD-SINAPIHYSFLSGNPPNYREFFEINPNTGAVKQIKAVDTTVTKRFDIIIKAVEV 337 Query: 233 GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR-------VQAYDAD 285 RS T +L I ++ V+ N P S + V EN PIG ++ + DAD Sbjct: 338 SEAKRSATAKLTITVKPVDSNPPIITASSIEGFVDENAPIGTKVIDKDGDPIVLTVSDAD 397 Query: 286 EGV-NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE--TQAKYQLLVTATDGG 342 G + + Y+ + T N IDP V LDR+ + +++ V A + Sbjct: 398 LGPDDPKPAYSF---ELTTNF---FAIDPSGMLVVNEENLDRDPPSPGRFRFQVVAREKT 451 Query: 343 DPPRSATATXXXXXXXXXXXXXXF-MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHY 401 SA + M V+ E + T V T D E+ + Y Sbjct: 452 GVAASAPLSFVVILNDVNDNAPMLPMIPPITVQAGETKKVVTK-VEATDNDEGENAEITY 510 Query: 402 EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN-IT 460 I + G G+I + L+ ++ + +TV ATD GG+ +V++N I Sbjct: 511 SIYHVSNNGLHKFKIDPRTGVIESVRKLNAGEQ--FSITVQATDKGGKYSQTIVEVNVIP 568 Query: 461 DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520 N +PVF+ Y V E A I +T+ +V A D + N ++YS+ S N+ Sbjct: 569 GPNTRSPVFQQPVYEVQVSEGASINSTMTIVHAVDPE---NDPVSYSIVS--GNDL---- 619 Query: 521 DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580 +QF I ++G IT + LDRE ++ Y L + A D G L T V I V D+ND P Sbjct: 620 -RQFAIGDKSGVITVIRKLDREDLTRYQLLIKAEDSG--GLFSTATVNIKVTDINDKNPE 676 Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640 F Y ++ E + +V A DAD G+N I Y P D F +DP +G + Sbjct: 677 FVGLPYEFSVKEGE-ARKLIGRVHAEDADEGINAEITY-FAPDDI---PFTVDPETGDVL 731 Query: 641 TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700 T LD E + A DG + +T V +K+ D+ D PVF + EN Sbjct: 732 TKIVLDYEQNDEYKFVVTARDGAPDYRLATATVTVKVIDVEDEVPVFHQSSYEARVKENI 791 Query: 701 PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760 P T+ ++ A DPD + Y IK G D+ F+++ R G K T LDYE Sbjct: 792 P-DYTVLQVTADDPD--TKKQITYMIKQG-DTELFAIDQRTGVIK----TTRGLDYERES 843 Query: 761 KKYELV--IRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVP 817 + ++ + S + RV + V DVND PV D P+G + Sbjct: 844 QHILIIGTVENTSDLPGSTTRVVVNVQDVNDIPPVFTSVPRPI-TLDDDIPIGTTVINLI 902 Query: 818 AYDADVT---DKLQYRILSGNNAN-LILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 A D+D T ++++Y I+ AN +++ TG + + L ++V D Sbjct: 903 ATDSDGTAPGNQVRYEIVGRGIANKYFMIDPDTGVLRVRDDLRKETDTEYQVDVRAYD 960 Score = 235 bits (576), Expect = 1e-59 Identities = 205/716 (28%), Positives = 325/716 (45%), Gaps = 43/716 (6%) Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121 I+ V D++N ++ F I+ +GA+ ++D R+ +++KA + Sbjct: 277 IQAVDMDSINAPIHYSFLSGNPPNYREFFEINPNTGAVKQIKAVDTTVTKRFDIIIKAVE 336 Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK------IK 175 + + S+TA + + + + N P + + VDE+ + VI K + Sbjct: 337 VSEA---KRSATAKLTITVKPVDSNPPIITASSIEGFVDENAPI-GTKVIDKDGDPIVLT 392 Query: 176 ATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS--YRLVIRAQDGG 233 +DAD+G + + A T F+ID V + LD + +R + A++ Sbjct: 393 VSDADLGPDDP-KPAYSFELTTNFFAIDPSGMLVVNEENLDRDPPSPGRFRFQVVAREKT 451 Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293 + S ++ + DVNDNAP + + + +V+A D DEG NAE+T Sbjct: 452 GVAASAPLSFVVILNDVNDNAPML--PMIPPITVQAGETKKVVTKVEATDNDEGENAEIT 509 Query: 294 YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353 Y++ G I DPR+G + + +L+ Q + + V ATD G S T Sbjct: 510 YSIYHVSNNGLHKFKI--DPRTGVIESVRKLNAGEQ--FSITVQATDKGGK-YSQTIVEV 564 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS 413 F YEV+++E + + + A D + D + Y I GN +F+ Sbjct: 565 NVIPGPNTRSPVFQQPVYEVQVSEGASINSTMTIVHAVDPENDP-VSYSIVSGNDLRQFA 623 Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAP 473 I ++G +ITV + LD + RY L + A DSGG TA V I +TD N+ P F P Sbjct: 624 IGDKSG--VITVIRKLDREDLTRYQLLIKAEDSGGLFSTATVNIKVTDINDKNPEFVGLP 681 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 Y SV ++ + V A D+D GINA+ITY A D F ++P+TG + Sbjct: 682 YEFSV-KEGEARKLIGRVHAEDADEGINAEITY----------FAPDDIPFTVDPETGDV 730 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593 T +LD E Y VTARDG T V + V+DV D PVF Q Y A + E+ Sbjct: 731 LTKIVLDYEQNDEYKFVVTARDGAPDYRLATATVTVKVIDVEDEVPVFHQSSYEARVKEN 790 Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653 + +V QV A D D +I Y + D E F ID +GVI+T + LD E + H Sbjct: 791 -IPDYTVLQVTADDPDT--KKQITYMIKQGDTE--LFAIDQRTGVIKTTRGLDYERESQH 845 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713 L ++ + ST V + ++D+ND PPVF S + ++ PIGTT+ + A D Sbjct: 846 ILIIGTVENTSDLPGSTTRVVVNVQDVNDIPPVFTSVPRPITLDDDIPIGTTVINLIATD 905 Query: 714 PD-EGPNAVVHYSIKGGDDSNSFSL---ETRQGSDKAELVTMVDLDYESPRKKYEL 765 D P V Y I G +N + + +T + +L D +Y+ + Y++ Sbjct: 906 SDGTAPGNQVRYEIVGRGIANKYFMIDPDTGVLRVRDDLRKETDTEYQVDVRAYDM 961 Score = 203 bits (495), Expect = 6e-50 Identities = 246/918 (26%), Positives = 392/918 (42%), Gaps = 85/918 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V + + P+ E V E A GT V+ D+D + T+ AD L Sbjct: 350 ITVKPVDSNPPIITASSIEGFVDENAPIGTKVI-----DKD---GDPIVLTVS--DAD-L 398 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA--RYTVLVKATDQASPVSD 128 P+D + F ID ++ +LDR+ + R+ V A ++ + Sbjct: 399 GPDDPKPAYSFELTT--NFFAIDPSGMLVVNEENLDRDPPSPGRFRFQVVAREKTGVAA- 455 Query: 129 RLSSTATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 S+ + V + D NDN P TV E V+ K++ATD D G N+ I Sbjct: 456 --SAPLSFVVILNDVNDNAPMLPMIPPITVQAGET-----KKVVTKVEATDNDEGENAEI 508 Query: 188 RYAI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 Y+I + N +F ID +G + V+ L+ + + + ++A D G ++ + Sbjct: 509 TYSIYHVSNNGLHKFKIDPRTGVIESVRKLNAGE--QFSITVQATDKGGKYSQTIVEVNV 566 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 I N +P F +++ VSE I ++ V A D + N ++Y++ +GN Sbjct: 567 -IPGPNTRSPVFQQPVYEVQVSEGASINSTMTIVHAVDPE---NDPVSYSIV----SGND 618 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 I +SG + +LDRE +YQLL+ A D G +TAT Sbjct: 619 LRQFAIGDKSGVITVIRKLDREDLTRYQLLIKAEDSGG--LFSTATVNIKVTDINDKNPE 676 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG-RFSITSQNGRGLIT 424 F+ YE + E E + + A DADE ++ EIT F++ + G L Sbjct: 677 FVGLPYEFSVKEGEARKL-IGRVHAEDADEG--INAEITYFAPDDIPFTVDPETGDVLTK 733 Query: 425 VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 + LD++Q Y V+A D R TA V + + D + PVF + Y A V E+ Sbjct: 734 IV--LDYEQNDEYKFVVTARDGAPDYRLATATVTVKVIDVEDEVPVFHQSSYEARVKENI 791 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 P TVL V+A D D QITY + + + F I+ +TG I T + LD E Sbjct: 792 P-DYTVLQVTADDPDT--KKQITYMIKQGDT--------ELFAIDQRTGVIKTTRGLDYE 840 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 S ++L + + TT V ++V DVND PVF + +D +GT+V Sbjct: 841 RESQHILIIGTVENTSDLPGSTTRVVVNVQDVNDIPPVFTSVPRPITLDDDIPIGTTVIN 900 Query: 603 VGATDADVGLNG-RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 + ATD+D G ++ YE+ + F+IDP +GV+R L +E+ + + A D Sbjct: 901 LIATDSDGTAPGNQVRYEIVGRGIANKYFMIDPDTGVLRVRDDLRKETDTEYQVDVRAYD 960 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPV----FESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 G P SS V + + + PP F + + E++ T I I + Sbjct: 961 MGEPQLSSVTTVPVYVRHVATVPPEIGLGFAENSYNVEVPEDAGDNTLIKIITIINSHAH 1020 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS-PPLWN 776 + I G++ + F + + A + LDYE+ + Y++ I+ S L N Sbjct: 1021 DTTPLKCEIYSGNEDDLFEAGVTEERNCALKLKKGALDYET-TESYQVKIKLESLSGLLN 1079 Query: 777 DVR----VEILVTDVNDNAPVM----KDFQIIFNNYKDCFP-VGPFG----RVPAYDAD- 822 R V+I V DVNDN P D ++ Y P FG +V A+D D Sbjct: 1080 SGRNTTMVKIQVVDVNDNKPEFIFPENDLKLSRGRYFAAIPRSAQFGSTVIQVKAHDKDN 1139 Query: 823 -VTDKLQYRILSGNNANLILLNETTGSM-TLSPQLNTNVPKLA-TMEVSVTDGVNEI--- 876 KL+YRIL G ++ ++ ++G + T + N + +L +V V D N Sbjct: 1140 GKYGKLEYRILGGRGSDYFAMDTSSGIIRTTATFDNVDPAELPFKFDVRVRDNPNSTDNF 1199 Query: 877 -KAMMQLSVRLITEEMLL 893 + + V LI EE L+ Sbjct: 1200 NSIVAPVIVNLIGEENLM 1217 Score = 184 bits (449), Expect = 2e-44 Identities = 222/818 (27%), Positives = 349/818 (42%), Gaps = 97/818 (11%) Query: 87 QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146 Q F+++G+ LL D E ++ + T + + T + V + D NDN Sbjct: 52 QPRFKLNGKRLQLLEPLDRDDENLSHVVFQLSCTVKQT----NKKRTIPVIVRVSDINDN 107 Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI-------IGGNTQM- 198 P+F Y +V E ++ + + + A DAD G N + Y+I IG N + Sbjct: 108 APKFINTPYETTVPE-LTPVGSTIFKNVVAVDADAGVNGIVEYSIAPGDGTGIGNNDGVG 166 Query: 199 -----------QFSID-SLSGDVSLVKTLDYEQVRSYRLVIRAQDGG---SPSRSNTTQL 243 FSI+ G V++ +TLD+E+ + Y + I A D S ++TT L Sbjct: 167 RNRITTADGYGYFSINLPHQGQVTVNRTLDFERTQRYLVTILASDRARNVSERFTSTTTL 226 Query: 244 LINIRDVNDNAPRF-YTSL-----------FQESVSENVPIG---YSIVRVQAYDADEGV 288 +NIRD +D P F Y + SVS V G S ++QA D D + Sbjct: 227 TVNIRDDDDQDPSFIYQGCMLLDGACINPEYSASVSSGVLSGILNISPEKIQAVDMD-SI 285 Query: 289 NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348 NA + Y+ + N I+P +G V +D ++ +++ A + + RSA Sbjct: 286 NAPIHYSFLSGN-PPNYREFFEINPNTGAVKQIKAVDTTVTKRFDIIIKAVEVSEAKRSA 344 Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV-------VTLTATDAD---EDNR 398 TA E + E+ P GT V + LT +DAD +D + Sbjct: 345 TAKLTITVKPVDSNPPIITASSIEGFVDENAPIGTKVIDKDGDPIVLTVSDADLGPDDPK 404 Query: 399 LHYEITGGNTRGRFSITSQNGRGLITVAQ---PLDFKQERRYVLTVSATDSGGRSDTAMV 455 Y T F+I + G++ V + D R+ V A + G + +A + Sbjct: 405 PAYSFE--LTTNFFAI---DPSGMLVVNEENLDRDPPSPGRFRFQVVAREKTGVAASAPL 459 Query: 456 Q--INITDANNYAPVFEN-APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512 + + D N+ AP+ P T E + V V ATD+D G NA+ITYS+ + Sbjct: 460 SFVVILNDVNDNAPMLPMIPPITVQAGETKKV---VTKVEATDNDEGENAEITYSI-YHV 515 Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572 SN + +F I+P+TG I + + L+ + +TV A D G T VE++V+ Sbjct: 516 SNNGL----HKFKIDPRTGVIESVRKLNAGEQ--FSITVQATDKG--GKYSQTIVEVNVI 567 Query: 573 -DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631 N PVF+Q +Y + E A + ++++ V A D + N + Y + + F Sbjct: 568 PGPNTRSPVFQQPVYEVQVSEGASINSTMTIVHAVDPE---NDPVSYSI-VSGNDLRQFA 623 Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691 I SGVI + LDRE + + L A D G ST V+IK+ DIND P F Sbjct: 624 IGDKSGVITVIRKLDREDLTRYQLLIKAEDSG--GLFSTATVNIKVTDINDKNPEFVGLP 681 Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751 F + E IG + A D DEG NA + Y D F+++ G +++T Sbjct: 682 YEFSVKEGE-ARKLIGRVHAEDADEGINAEITYF---APDDIPFTVDPETG----DVLTK 733 Query: 752 VDLDYE-SPRKKYELVIRAASPPL-WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809 + LDYE + K+ + R +P V + V DV D PV K+ P Sbjct: 734 IVLDYEQNDEYKFVVTARDGAPDYRLATATVTVKVIDVEDEVPVFHQ-SSYEARVKENIP 792 Query: 810 VGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTG 847 +V A D D ++ Y I G + L +++ TG Sbjct: 793 DYTVLQVTADDPDTKKQITYMIKQG-DTELFAIDQRTG 829 Score = 119 bits (286), Expect = 1e-24 Identities = 128/454 (28%), Positives = 209/454 (46%), Gaps = 68/454 (14%) Query: 394 DEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER--RYVLTVSAT-DSGGRS 450 D N E+ + RF + NG+ L + +PLD E V +S T + Sbjct: 37 DPYNETTLELIFPGRQPRFKL---NGKRL-QLLEPLDRDDENLSHVVFQLSCTVKQTNKK 92 Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV-VSATDSDVGINAQITYSLS 509 T V + ++D N+ AP F N PY +V E P+G+T+ V A D+D G+N + YS++ Sbjct: 93 RTIPVIVRVSDINDNAPKFINTPYETTVPELTPVGSTIFKNVVAVDADAGVNGIVEYSIA 152 Query: 510 ----SEISNE--------AVAHHDQQFVIN-PQTGAITTNKLLDRETMSGYLLTVTARDG 556 + I N A F IN P G +T N+ LD E YL+T+ A D Sbjct: 153 PGDGTGIGNNDGVGRNRITTADGYGYFSINLPHQGQVTVNRTLDFERTQRYLVTILASDR 212 Query: 557 G---VPSLSDTTDVEISVVDVNDNEPVFKQQ------------LYTANIMEDALVG---T 598 + TT + +++ D +D +P F Q Y+A++ L G Sbjct: 213 ARNVSERFTSTTTLTVNIRDDDDQDPSFIYQGCMLLDGACINPEYSASVSSGVLSGILNI 272 Query: 599 SVSQVGATDADVGLNGRIHYEL---DPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655 S ++ A D D +N IHY +P + E F I+P +G ++ KA+D D+ Sbjct: 273 SPEKIQAVDMD-SINAPIHYSFLSGNPPNYRE-FFEINPNTGAVKQIKAVDTTVTKRFDI 330 Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 A++ +S+T + I ++ ++ +PP+ + + ++ EN+PIGT + D D Sbjct: 331 IIKAVEVSEAKRSATAKLTITVKPVDSNPPIITASSIEGFVDENAPIGT-----KVIDKD 385 Query: 716 EGPNAV-VHYSIKGGDD---SNSFSLETR-QGSDKAELVTM----VDLDYESP-RKKYEL 765 P + V + G DD + SF L T D + ++ + +D D SP R ++++ Sbjct: 386 GDPIVLTVSDADLGPDDPKPAYSFELTTNFFAIDPSGMLVVNEENLDRDPPSPGRFRFQV 445 Query: 766 VIR-----AASPPLWNDVRVEILVTDVNDNAPVM 794 V R AAS PL +++ DVNDNAP++ Sbjct: 446 VAREKTGVAASAPL----SFVVILNDVNDNAPML 475 Score = 37.5 bits (83), Expect = 5.3 Identities = 22/62 (35%), Positives = 34/62 (54%), Gaps = 9/62 (14%) Query: 10 QINVLDCNDHSPVF---------EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEY 60 +I V+D ND+ P F +Y A++ A G+TV+ +KA D+D GK ++EY Sbjct: 1088 KIQVVDVNDNKPEFIFPENDLKLSRGRYFAAIPRSAQFGSTVIQVKAHDKDNGKYGKLEY 1147 Query: 61 TI 62 I Sbjct: 1148 RI 1149 >UniRef50_Q60I71 Cluster: Cadherin-related neuronal receptor variable 6; n=16; Clupeocephala|Rep: Cadherin-related neuronal receptor variable 6 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 939 Score = 255 bits (625), Expect = 1e-65 Identities = 182/601 (30%), Positives = 280/601 (46%), Gaps = 31/601 (5%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F ++ ++G L + LDRE++ ++ K + + + + VN++D NDN P Sbjct: 72 FDVNMKTGILQVKDKLDREEICGQSL--KCALELEAIVNSPLNMYRFEVNVLDVNDNSPT 129 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG-- 207 F ++V E + + + A DADVG NS Y + + FS+D+ SG Sbjct: 130 FPSSRLQLNVSEAAFIGERYALPN--AFDADVGINSVKSYKL---SANEHFSLDAQSGGE 184 Query: 208 -----DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLF 262 ++ L K LD E+ RL + A DGG P RS T +++N+ DVNDN P F SL+ Sbjct: 185 QSVSAELVLQKALDREKQPVIRLTLTAVDGGKPPRSGTVHIIVNVIDVNDNIPVFTKSLY 244 Query: 263 QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322 + + EN P+ +S++ V A DAD G+N E+ Y+ N++ I+ +G + G Sbjct: 245 KARILENAPVEFSVITVNARDADAGLNGEIEYSFIKHGIDKNIE-SFAINKETGEITVMG 303 Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382 +LD E+ ++ V A D G PR A + E P G Sbjct: 304 KLDHESNNAIEIRVQARDKGSTPRVAHCKVLVEIMDVNDNIPEISVTSLINVVKEGSPKG 363 Query: 383 TPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440 T V +T D D E+ + +I + T +N L+ V PLD + Y +T Sbjct: 364 TMVGLITVKDDDSGENGSVKLKIL-DSLPFALQNTYKNKYSLV-VDGPLDRESASEYNVT 421 Query: 441 VSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498 +SA D G S T+++ ++++D N+ AP F V E++ IG + VSA D DV Sbjct: 422 ISAADEGSPPLSSTSVIAVHVSDVNDNAPRFPEPVINVYVKENSQIGAVLHTVSAVDPDV 481 Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558 G NA+ITYSL + V IN TG + + + + E + + V A D GV Sbjct: 482 GDNARITYSLLESSKSGPVT---SMININSDTGDLHSLQSFNYEEIKTFEFKVQATDSGV 538 Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQ------QLYTANIMEDALVGTSVSQVGATDADVGL 612 P LS V + V+D NDN P + T NI A G V+++ A DAD G Sbjct: 539 PPLSSNVTVNVFVLDENDNSPAILAPYSELGSVNTENIPYSAEAGYFVAKIRAVDADSGY 598 Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672 N + Y + + + F I +SG IRT + + + TH L + D G P S+TV Sbjct: 599 NALLSYHIS-EPKGNNLFRIGTSSGEIRTKRRMSDNDLKTHPLVILVCDNGEPSLSATVS 657 Query: 673 V 673 + Sbjct: 658 I 658 Score = 194 bits (472), Expect = 4e-47 Identities = 140/479 (29%), Positives = 230/479 (48%), Gaps = 26/479 (5%) Query: 412 FSITSQNG-----RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANN 464 FS+ +Q+G + + + LD +++ LT++A D G RS T + +N+ D N+ Sbjct: 175 FSLDAQSGGEQSVSAELVLQKALDREKQPVIRLTLTAVDGGKPPRSGTVHIIVNVIDVND 234 Query: 465 YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524 PVF + Y A + E+AP+ +V+ V+A D+D G+N +I YS + + + F Sbjct: 235 NIPVFTKSLYKARILENAPVEFSVITVNARDADAGLNGEIEYSFIKH----GIDKNIESF 290 Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584 IN +TG IT LD E+ + + V ARD G V + ++DVNDN P Sbjct: 291 AINKETGEITVMGKLDHESNNAIEIRVQARDKGSTPRVAHCKVLVEIMDVNDNIPEISVT 350 Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGVIRTNK 643 + E + GT V + D D G NG + + LD + + S V+ + Sbjct: 351 SLINVVKEGSPKGTMVGLITVKDDDSGENGSVKLKILDSLPFALQNTYKNKYSLVV--DG 408 Query: 644 ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703 LDRES + +++ A D G+PP SST ++ + + D+ND+ P F + Y+ ENS IG Sbjct: 409 PLDRESASEYNVTISAADEGSPPLSSTSVIAVHVSDVNDNAPRFPEPVINVYVKENSQIG 468 Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY 763 + + A DPD G NA + YS+ S + SD +L ++ +YE K + Sbjct: 469 AVLHTVSAVDPDVGDNARITYSLLESSKSGPVTSMININSDTGDLHSLQSFNYEE-IKTF 527 Query: 764 ELVIRAAS---PPLWNDVRVEILVTDVNDNAP-VMKDFQIIFNNYKDCFP----VGPF-G 814 E ++A PPL ++V V + V D NDN+P ++ + + + + P G F Sbjct: 528 EFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAILAPYSELGSVNTENIPYSAEAGYFVA 587 Query: 815 RVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 ++ A DAD L Y I NL + ++G + +++ N K + + V D Sbjct: 588 KIRAVDADSGYNALLSYHISEPKGNNLFRIGTSSGEIRTKRRMSDNDLKTHPLVILVCD 646 Score = 185 bits (450), Expect = 2e-44 Identities = 159/583 (27%), Positives = 257/583 (44%), Gaps = 54/583 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++NVLD ND+SP F + + +V E A G A D D+G N+ Y + + Sbjct: 117 EVNVLDVNDNSPTFPSSRLQLNVSEAAFIGERYALPNAFDADVGINSVKSYKLSANEHFS 176 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L+ + Q V S L+ + +LDREK + + A D P Sbjct: 177 LDAQSGGE---------QSV------SAELVLQKALDREKQPVIRLTLTAVDGGKPPR-- 219 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S T I VN+ID NDN P F++ Y + E+ V + + + A DAD G N I Y Sbjct: 220 -SGTVHIIVNVIDVNDNIPVFTKSLYKARILENAPVEFS--VITVNARDADAGLNGEIEY 276 Query: 190 AII--GGNTQMQ-FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 + I G + ++ F+I+ +G+++++ LD+E + + ++A+D GS R ++L+ Sbjct: 277 SFIKHGIDKNIESFAINKETGEITVMGKLDHESNNAIEIRVQARDKGSTPRVAHCKVLVE 336 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 I DVNDN P + V E P G + + D D G N + + D Sbjct: 337 IMDVNDNIPEISVTSLINVVKEGSPKGTMVGLITVKDDDSGENGSVKLKILDS------- 389 Query: 307 LPITIDPRSGWVYT---SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 LP + Y+ G LDRE+ ++Y + ++A D G PP S+T+ Sbjct: 390 LPFALQNTYKNKYSLVVDGPLDRESASEYNVTISAADEGSPPLSSTSVIAVHVSDVNDNA 449 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRGRFS--ITSQNG 419 F V + E+ G + T++A D D DN R+ Y + + G + I + Sbjct: 450 PRFPEPVINVYVKENSQIGAVLHTVSAVDPDVGDNARITYSLLESSKSGPVTSMININSD 509 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPY--- 474 G + Q ++++ + + V ATDSG S V + + D N+ +P APY Sbjct: 510 TGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNSPAIL-APYSEL 568 Query: 475 ----TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 T ++ A G V + A D+D G NA ++Y +S N F I + Sbjct: 569 GSVNTENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKGNNL-------FRIGTSS 621 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 G I T + + + + L + D G PSLS T ++ VV+ Sbjct: 622 GEIRTKRRMSDNDLKTHPLVILVCDNGEPSLSATVSIDAVVVE 664 Score = 154 bits (374), Expect = 3e-35 Identities = 137/502 (27%), Positives = 220/502 (43%), Gaps = 40/502 (7%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 +H +NV+D ND+ PVF Y+A + E A +V+T+ A D D G N E+EY+ Sbjct: 223 VHIIVNVIDVNDNIPVFTKSLYKARILENAPVEFSVITVNARDADAGLNGEIEYSFIKHG 282 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 D N E F I+ +G + LD E + V+A D+ S Sbjct: 283 IDK-NIES---------------FAINKETGEITVMGKLDHESNNAIEIRVQARDKGS-- 324 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 + R++ + V I+D NDN P+ S T ++V ++ S ++ I D D G N + Sbjct: 325 TPRVAHCKVL-VEIMDVNDNIPEISV-TSLINVVKEGS-PKGTMVGLITVKDDDSGENGS 381 Query: 187 IRYAIIGGNTQMQFSI-DSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 ++ I+ + F++ ++ SLV LD E Y + I A D GSP S+T+ + Sbjct: 382 VKLKILDS---LPFALQNTYKNKYSLVVDGPLDRESASEYNVTISAADEGSPPLSSTSVI 438 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 +++ DVNDNAPRF + V EN IG + V A D D G NA +TY++ + +G Sbjct: 439 AVHVSDVNDNAPRFPEPVINVYVKENSQIGAVLHTVSAVDPDVGDNARITYSLLESSKSG 498 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 V I I+ +G +++ + E ++ V ATD G PP S+ T Sbjct: 499 PVTSMININSDTGDLHSLQSFNYEEIKTFEFKVQATDSGVPPLSSNVTVNVFVLDENDNS 558 Query: 364 XXFMPGQYEVELAEDE------PPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSIT 415 + E+ E G V + A DAD + L Y I+ F I Sbjct: 559 PAILAPYSELGSVNTENIPYSAEAGYFVAKIRAVDADSGYNALLSYHISEPKGNNLFRIG 618 Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN---ITDANNYAPVFENA 472 + +G I + + + + L + D+G S +A V I+ + + F +A Sbjct: 619 TSSGE--IRTKRRMSDNDLKTHPLVILVCDNGEPSLSATVSIDAVVVESGGDVKTPFRHA 676 Query: 473 PYTASVFEDAPIGTTVLVVSAT 494 P F D + + +VS + Sbjct: 677 PVKEESFSDLNLYLLIAIVSVS 698 Score = 141 bits (341), Expect = 3e-31 Identities = 116/370 (31%), Positives = 169/370 (45%), Gaps = 24/370 (6%) Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523 N P + SV E+A GTTV + ++ +N Q +I V + + Sbjct: 19 NILPRISSGQIAFSVSEEASPGTTVGNIV---KELNLNLQELEHRGFQI----VGPNKRY 71 Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVNDNEPVFK 582 F +N +TG + LDRE + G L + V S + E++V+DVNDN P F Sbjct: 72 FDVNMKTGILQVKDKLDREEICGQSLKCALELEAIVNSPLNMYRFEVNVLDVNDNSPTFP 131 Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR---EEGSFVIDPASGVI 639 N+ E A +G + A DADVG+N Y+L + + S S + Sbjct: 132 SSRLQLNVSEAAFIGERYALPNAFDADVGINSVKSYKLSANEHFSLDAQSGGEQSVSAEL 191 Query: 640 RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699 KALDRE L A+DGG PP+S TV + + + D+ND+ PVF I EN Sbjct: 192 VLQKALDREKQPVIRLTLTAVDGGKPPRSGTVHIIVNVIDVNDNIPVFTKSLYKARILEN 251 Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYS-IKGGDDSN--SFSLETRQGSDKAELVTMVDLDY 756 +P+ ++ + A D D G N + YS IK G D N SF++ G E+ M LD+ Sbjct: 252 APVEFSVITVNARDADAGLNGEIEYSFIKHGIDKNIESFAINKETG----EITVMGKLDH 307 Query: 757 ESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF 813 ES E+ ++A S P +V + + DVNDN P + +I N K+ P G Sbjct: 308 ES-NNAIEIRVQARDKGSTPRVAHCKVLVEIMDVNDNIPEISVTSLI-NVVKEGSPKGTM 365 Query: 814 -GRVPAYDAD 822 G + D D Sbjct: 366 VGLITVKDDD 375 Score = 77.0 bits (181), Expect = 7e-12 Identities = 74/295 (25%), Positives = 123/295 (41%), Gaps = 17/295 (5%) Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648 ++ E+A GT+V + + ++ L H + F ++ +G+++ LDRE Sbjct: 32 SVSEEASPGTTVGNI-VKELNLNLQELEHRGFQIVGPNKRYFDVNMKTGILQVKDKLDRE 90 Query: 649 SVATHDLK-AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 + LK A+ ++ + + + D+ND+ P F S L +SE + IG Sbjct: 91 EICGQSLKCALELEAIVNSPLNMYRFEVNVLDVNDNSPTFPSSRLQLNVSEAAFIGERYA 150 Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK---AELVTMVDLDYE-SPRKKY 763 A D D G N+V Y + + FSL+ + G ++ AELV LD E P + Sbjct: 151 LPNAFDADVGINSVKSYKLSANE---HFSLDAQSGGEQSVSAELVLQKALDREKQPVIRL 207 Query: 764 EL-VIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQI---IFNNYKDCFPVGPFGRVPAY 819 L + PP V + + V DVNDN PV I N F V A Sbjct: 208 TLTAVDGGKPPRSGTVHIIVNVIDVNDNIPVFTKSLYKARILENAPVEFSVITVNARDA- 266 Query: 820 DADVTDKLQYRILS---GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 DA + +++Y + N +N+ TG +T+ +L+ + V D Sbjct: 267 DAGLNGEIEYSFIKHGIDKNIESFAINKETGEITVMGKLDHESNNAIEIRVQARD 321 Score = 37.5 bits (83), Expect = 5.3 Identities = 43/174 (24%), Positives = 76/174 (43%), Gaps = 7/174 (4%) Query: 685 PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK-GGDDSNSFSLETRQG- 742 P S + F +SE + GTT+G I + + + H + G + F + + G Sbjct: 22 PRISSGQIAFSVSEEASPGTTVGNI-VKELNLNLQELEHRGFQIVGPNKRYFDVNMKTGI 80 Query: 743 SDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN 802 + + ++ +S + EL SP N R E+ V DVNDN+P ++ N Sbjct: 81 LQVKDKLDREEICGQSLKCALELEAIVNSP--LNMYRFEVNVLDVNDNSPTFPSSRLQLN 138 Query: 803 NYKDCFPVGPFGRVPAYDADV-TDKLQYRILSGNNANLILLNETTGSMTLSPQL 855 + F + A+DADV + ++ LS N + L ++ G ++S +L Sbjct: 139 VSEAAFIGERYALPNAFDADVGINSVKSYKLSANE-HFSLDAQSGGEQSVSAEL 191 >UniRef50_Q7PUW9 Cluster: ENSANGP00000018135; n=2; Anopheles gambiae|Rep: ENSANGP00000018135 - Anopheles gambiae str. PEST Length = 1880 Score = 254 bits (621), Expect = 3e-65 Identities = 222/765 (29%), Positives = 344/765 (44%), Gaps = 72/765 (9%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKAT-----DQDIGKNAEVEYTIELVTA 67 V D ND P F YE + E A T + + D D GKN T L Sbjct: 387 VTDVNDEIPRFRSDGYECEIGENAQENTLARFIDGSINEVFDYDQGKNG----TFRL--- 439 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 +L+P + F + + ++ LD E+V ++ V A++ S + Sbjct: 440 -SLHPPSDIFEVIPKRAINEATFGLRVKDPSM-----LDYERVRELSLTVVASEVES--A 491 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG--ANS 185 R +STA I V ++D NDN+P+FS+ Y + V E +VT V+ +++ATD+D G Sbjct: 492 GR-TSTAQIRVVVLDQNDNFPEFSQPVYEIDVPE--NVTAGTVLLQLQATDSDSGLFGTE 548 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKT----LDYEQVRSYRLVIRAQDGGSPSRSNTT 241 +RYA + G+ +D +G V+L+ + D E ++ + L + A+D G NT Sbjct: 549 GVRYANLTGSISSFLHLDPHAGTVTLMASESPVFDREIIQKHYLSVEARDNGGRGNRNTV 608 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EG-VNAELTYTMT-- 297 L++N+ DVNDNAP F ++ + EN S + V+A D+D EG N+ + Y + Sbjct: 609 PLILNVLDVNDNAPVFVQKRYEVRLKENAFEFESPIVVEARDSDLEGSPNSAVEYRLIGA 668 Query: 298 -DKDY------TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350 DY TG + + +D + G D T A L + A DGG+PP +A Sbjct: 669 HHSDYFHVDRRTGRLSVREAVD-FERLESSGGSGDTRTIA---LTIEAADGGEPPLTAQV 724 Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGN 407 F+ QY + + ED P G PV+ +TA D D +N + Y I G Sbjct: 725 EVTVYVQDVNDYAPVFLESQYAIVIPEDTPSGLPVLRVTAMDGDGSFPNNHVTYRIQQGG 784 Query: 408 TRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAP 467 GRF I + G IT LD + A D+ G T ++++ TD N Sbjct: 785 D-GRFVIGASTGEISITHGASLD--------PNLLAPDALGSGSTYVLEVFATDGGNGDQ 835 Query: 468 VFENAPYTASVFEDAPIGTTVLVVSATDSDVG--INAQITYSLSSEISNE-AVAHHDQ-- 522 + + + + P+GT V + ATD D G + I SLS + E A+ D Sbjct: 836 QLQG----SCLVNNTPVGTEVYRLMATDPDEGAMLRYYIDRSLSEGKTEEGALVKLDDYD 891 Query: 523 ---QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP--SLSDTTDVEISVVDVNDN 577 F++N G + KLLDRE ++ L D T ++I+V+D NDN Sbjct: 892 FAAAFILNETNGLLKIAKLLDREKIAEIKLACVVEDVAAERGDQMANTFLKITVLDENDN 951 Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637 P F++ Y +I E++ G +V V A DAD N + Y L+ + +D +G Sbjct: 952 NPKFRKPFYKHSIAENSQYGVAVCTVVAEDAD--QNKTVKYSLEGEKGVLELLHVDDETG 1009 Query: 638 VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697 I +D E + + A D GTPP++S V V +++ D ND+ P F +Y+S Sbjct: 1010 EIVVRNRIDHEEYSWLNFSVRAADTGTPPRASFVEVFVQVLDENDNNPYFVDSVNDYYVS 1069 Query: 698 ENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 EN+ +G I I A D D G + Y + FS++ +G Sbjct: 1070 ENASVGAEIAIILAKDLDSGDFGRITYILDRVSSKEKFSIDPEKG 1114 Score = 245 bits (600), Expect = 1e-62 Identities = 240/906 (26%), Positives = 393/906 (43%), Gaps = 89/906 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ VLD ND+ P F YE V E ++GT +L L+ATD D G + E V Sbjct: 500 RVVVLDQNDNFPEFSQPVYEIDVPENVTAGTVLLQLQATDSDSGL-----FGTEGVRYAN 554 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS----LDREKVARYTVLVKATDQASP 125 L + +D +G + AS DRE + ++ + V+A D Sbjct: 555 L------------TGSISSFLHLDPHAGTVTLMASESPVFDREIIQKHYLSVEARDNGGR 602 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 + +T + +N++D NDN P F +K Y V + E+ ++P++ + + +D + NS Sbjct: 603 GN---RNTVPLILNVLDVNDNAPVFVQKRYEVRLKENAFEFESPIVVEARDSDLEGSPNS 659 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV---------RSYRLVIRAQDGGSPS 236 A+ Y +IG + F +D +G +S+ + +D+E++ R+ L I A DGG P Sbjct: 660 AVEYRLIGAHHSDYFHVDRRTGRLSVREAVDFERLESSGGSGDTRTIALTIEAADGGEPP 719 Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV-NAELTYT 295 + ++ + ++DVND AP F S + + E+ P G ++RV A D D N +TY Sbjct: 720 LTAQVEVTVYVQDVNDYAPVFLESQYAIVIPEDTPSGLPVLRVTAMDGDGSFPNNHVTYR 779 Query: 296 MT---DKDY-----TGNVDLP--ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP 345 + D + TG + + ++DP + L + + Y L V ATDGG+ Sbjct: 780 IQQGGDGRFVIGASTGEISITHGASLDPN---LLAPDALG--SGSTYVLEVFATDGGNGD 834 Query: 346 RSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV---VTLTATDADEDNRLHYE 402 + + M A D G + + + ++ + + Sbjct: 835 QQLQGSCLVNNTPVGTEVYRLM--------ATDPDEGAMLRYYIDRSLSEGKTEEGALVK 886 Query: 403 ITGGNTRGRFSITSQNGRGLITVAQPLDFKQ--ERRYVLTVS--ATDSGGRSDTAMVQIN 458 + + F + N GL+ +A+ LD ++ E + V A + G + ++I Sbjct: 887 LDDYDFAAAFILNETN--GLLKIAKLLDREKIAEIKLACVVEDVAAERGDQMANTFLKIT 944 Query: 459 ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518 + D N+ P F Y S+ E++ G V V A D+D N + YSL E + Sbjct: 945 VLDENDNNPKFRKPFYKHSIAENSQYGVAVCTVVAEDADQ--NKTVKYSLEGEKGVLELL 1002 Query: 519 HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578 H ++ +TG I +D E S +V A D G P + +V + V+D NDN Sbjct: 1003 H------VDDETGEIVVRNRIDHEEYSWLNFSVRAADTGTPPRASFVEVFVQVLDENDNN 1056 Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638 P F + + E+A VG ++ + A D D G GRI Y LD +E F IDP G+ Sbjct: 1057 PYFVDSVNDYYVSENASVGAEIAIILAKDLDSGDFGRITYILDRVSSKE-KFSIDPEKGI 1115 Query: 639 IRTNKALDRESVATHDLKAVAID----GGTPPQSSTVIVHIKIE--DINDSPPVFESDCL 692 +R ALDRE A + L A D G +S HI I D ND+ PV + Sbjct: 1116 LRVAGALDREETAEYMLAVEAWDNYPYGYLNGESRNAFKHILIHVLDDNDNVPVIQKPSG 1175 Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752 I+E I I ++RA D D+ N S D S F ++ + + AE+ + Sbjct: 1176 CSMITEYHNINDPIVKLRATDADDPTNGNGQLSFDIVDPSGIFYIQ-QVSAQYAEIYSRG 1234 Query: 753 DLDYESPRKKYELVIR-AASPPLWNDVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFP 809 L EL++ P V+I VTD ND+AP V+ +++ Sbjct: 1235 PLKNLHGNYTLELIVSDLGGVPNTARETVDICVTDFNDHAPVFVVPSGNTTVKVFENTTL 1294 Query: 810 VGPFGRVPAYDADVTDK--LQYRILSGNNANL--ILLNETTGSMTLSPQLNTNVPKLATM 865 PF +V AYD DV + ++YR+ N L++ TG ++L+ L+ + + Sbjct: 1295 GKPFFQVHAYDEDVGENAIVRYRLKMDTMGNFRKFSLDKETGELSLAASLDREQQMMYDL 1354 Query: 866 EVSVTD 871 + D Sbjct: 1355 RIEAYD 1360 Score = 239 bits (584), Expect = 1e-60 Identities = 210/718 (29%), Positives = 323/718 (44%), Gaps = 53/718 (7%) Query: 39 GTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGA 98 GT V L ATD D G A + Y I+ ++ E A F ++ +G Sbjct: 849 GTEVYRLMATDPDEG--AMLRYYIDRSLSEGKTEEGALVKLDDYDFAA--AFILNETNGL 904 Query: 99 LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158 L LDREK+A + D A+ D++++T + + ++D+NDN P+F + Y S Sbjct: 905 LKIAKLLDREKIAEIKLACVVEDVAAERGDQMANTF-LKITVLDENDNNPKFRKPFYKHS 963 Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQF-SIDSLSGDVSLVKTLDY 217 + E+ + + A DAD N ++Y++ G ++ +D +G++ + +D+ Sbjct: 964 IAENSQY--GVAVCTVVAEDAD--QNKTVKYSLEGEKGVLELLHVDDETGEIVVRNRIDH 1019 Query: 218 EQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277 E+ +RA D G+P R++ ++ + + D NDN P F S+ VSEN +G I Sbjct: 1020 EEYSWLNFSVRAADTGTPPRASFVEVFVQVLDENDNNPYFVDSVNDYYVSENASVGAEIA 1079 Query: 278 RVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVT 337 + A D D G +TY + D + + +IDP G + +G LDRE A+Y L V Sbjct: 1080 IILAKDLDSGDFGRITYIL---DRVSSKE-KFSIDPEKGILRVAGALDREETAEYMLAVE 1135 Query: 338 ATDG------GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTAT 391 A D R+A + E P+V L AT Sbjct: 1136 AWDNYPYGYLNGESRNAFKHILIHVLDDNDNVPVIQKPSGCSMITEYHNINDPIVKLRAT 1195 Query: 392 DADE----DNRLHYEITGGNTRGRFSITSQNGR-GLITVAQPLDFKQERRYVLTVSATDS 446 DAD+ + +L ++I + G F I + + I PL Y L + +D Sbjct: 1196 DADDPTNGNGQLSFDIV--DPSGIFYIQQVSAQYAEIYSRGPLK-NLHGNYTLELIVSDL 1252 Query: 447 GGRSDTAM--VQINITDANNYAPVF--ENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502 GG +TA V I +TD N++APVF + T VFE+ +G V A D DVG NA Sbjct: 1253 GGVPNTARETVDICVTDFNDHAPVFVVPSGNTTVKVFENTTLGKPFFQVHAYDEDVGENA 1312 Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS-L 561 + Y L + ++F ++ +TG ++ LDRE Y L + A D G+P+ L Sbjct: 1313 IVRYRLKMDTMGNF-----RKFSLDKETGELSLAASLDREQQMMYDLRIEAYDQGIPTPL 1367 Query: 562 SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT-DADV-----GLNGR 615 S T D+ + V DVNDN P F + + N E GT ++ T D D G Sbjct: 1368 SSTVDLIVYVRDVNDNLPQFLLKEISLNFTEHMTPGTERIRLPDTVDQDYLDPLDGPAAS 1427 Query: 616 IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG--------GTPPQ 667 + E+G F +DP S + K LDRE + + L A + T Sbjct: 1428 VVCYYIVHGNEDGHFGLDPVSHDLTVEKELDREKKSLYKLHIKATEECTNANLSLDTTSH 1487 Query: 668 SSTVI-VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 S ++ + I DIND+ PVFES T IS +S G TI +++A D D+G N +V Y Sbjct: 1488 SGNLLKATVYINDINDNSPVFESKIFTGGISTSSLFGATILQLQATDEDDGLNGLVRY 1545 Score = 201 bits (491), Expect = 2e-49 Identities = 193/678 (28%), Positives = 302/678 (44%), Gaps = 70/678 (10%) Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS 164 LDRE YT+++ TD + + T + + + D NDN P F + V ED Sbjct: 127 LDREAREEYTLILTLTD--GRLGEGNFVTQSFLLLVEDINDNEPIFKPFASVLEVAED-- 182 Query: 165 VTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ-FSIDSLSGD--VSLVKTLDYEQVR 221 + ++ ++A D D GA + Y I G + + FSI + +G V L + LDYE+ Sbjct: 183 -SPPGILTTLEAVDKDEGAYGQVVYYIQGLSEENNVFSISTSNGKGVVRLARALDYERQH 241 Query: 222 SYRLVIRAQDGGSPSRSN--TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIG------ 273 Y + + A D R N T LL+ ++DV D P F + +SE+ PIG Sbjct: 242 FYHINVLAVDRAIQGRINTGTAALLVRVKDVEDQPPEFLVTQPVVRISEDAPIGTEVASM 301 Query: 274 -YSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK- 331 YS+ V+A D D G+N + Y +++ N ID G + T +LDRE Sbjct: 302 IYSLSTVKAVDGDRGINNRIIYGISN-----NGSELFEIDRLKGSLRTKQKLDREDSTNP 356 Query: 332 ----YQLLVTATDGG--DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 + L V A + P S+T F YE E+ E+ T Sbjct: 357 INGAFILEVVAIEESKLQPAPSSTMEITVIVTDVNDEIPRFRSDGYECEIGENAQENTLA 416 Query: 386 VTLTAT-----DADEDNRLHYEITGGNTRGRFSITSQNGRGLIT----VAQP--LDFKQE 434 + + D D+ + ++ F + + T V P LD+++ Sbjct: 417 RFIDGSINEVFDYDQGKNGTFRLSLHPPSDIFEVIPKRAINEATFGLRVKDPSMLDYERV 476 Query: 435 RRYVLTV--SATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492 R LTV S +S GR+ TA +++ + D N+ P F Y V E+ GT +L + Sbjct: 477 RELSLTVVASEVESAGRTSTAQIRVVVLDQNDNFPEFSQPVYEIDVPENVTAGTVLLQLQ 536 Query: 493 ATDSDVGI--NAQITY-SLSSEISNEAVAHHDQQFVINPQTGAIT----TNKLLDRETMS 545 ATDSD G+ + Y +L+ IS + H ++P G +T + + DRE + Sbjct: 537 ATDSDSGLFGTEGVRYANLTGSIS--SFLH------LDPHAGTVTLMASESPVFDREIIQ 588 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 + L+V ARD G +T + ++V+DVNDN PVF Q+ Y + E+A S V A Sbjct: 589 KHYLSVEARDNGGRGNRNTVPLILNVLDVNDNAPVFVQKRYEVRLKENAFEFESPIVVEA 648 Query: 606 TDADV--GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE----SVATHDLKAVA 659 D+D+ N + Y L + F +D +G + +A+D E S + D + +A Sbjct: 649 RDSDLEGSPNSAVEYRLIGAHHSD-YFHVDRRTGRLSVREAVDFERLESSGGSGDTRTIA 707 Query: 660 I-----DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 + DGG PP ++ V V + ++D+ND PVF I E++P G + + A D Sbjct: 708 LTIEAADGGEPPLTAQVEVTVYVQDVNDYAPVFLESQYAIVIPEDTPSGLPVLRVTAMDG 767 Query: 715 DEG-PNAVVHYSIKGGDD 731 D PN V Y I+ G D Sbjct: 768 DGSFPNNHVTYRIQQGGD 785 Score = 192 bits (467), Expect = 2e-46 Identities = 246/944 (26%), Positives = 391/944 (41%), Gaps = 105/944 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDI--GKNAEVEYTIELVTAD 68 +NVLD ND++PVF ++YE ++E A + + ++A D D+ N+ VEY L+ A Sbjct: 612 LNVLDVNDNAPVFVQKRYEVRLKENAFEFESPIVVEARDSDLEGSPNSAVEY--RLIGAH 669 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARY-----TVLVKATDQA 123 D F +D R+G L R ++D E++ T + T +A Sbjct: 670 H-----------------SDYFHVDRRTGRLSVREAVDFERLESSGGSGDTRTIALTIEA 712 Query: 124 SPVSDR-LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 + + L++ + V + D ND P F E Y + + ED + + PV+ ++ A D D Sbjct: 713 ADGGEPPLTAQVEVTVYVQDVNDYAPVFLESQYAIVIPED-TPSGLPVL-RVTAMDGDGS 770 Query: 183 -ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVK--TLDYEQVR--------SYRLVIRAQD 231 N+ + Y I G +F I + +G++S+ +LD + +Y L + A D Sbjct: 771 FPNNHVTYRIQQGGDG-RFVIGASTGEISITHGASLDPNLLAPDALGSGSTYVLEVFATD 829 Query: 232 GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE 291 GG+ + L+N V R L E + Y I R EG E Sbjct: 830 GGNGDQQLQGSCLVNNTPVGTEVYR----LMATDPDEGAMLRYYIDR----SLSEGKTEE 881 Query: 292 LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVT----ATDGGDPPRS 347 D DY + ++ +G + + LDRE A+ +L A + GD + Sbjct: 882 GALVKLD-DY--DFAAAFILNETNGLLKIAKLLDREKIAEIKLACVVEDVAAERGD--QM 936 Query: 348 ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGN 407 A F Y+ +AE+ G V T+ A DAD++ + Y + G Sbjct: 937 ANTFLKITVLDENDNNPKFRKPFYKHSIAENSQYGVAVCTVVAEDADQNKTVKYSLEG-- 994 Query: 408 TRGRFSITSQNGR-GLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANN 464 +G + + G I V +D ++ +V A D+G R+ V + + D N+ Sbjct: 995 EKGVLELLHVDDETGEIVVRNRIDHEEYSWLNFSVRAADTGTPPRASFVEVFVQVLDEND 1054 Query: 465 YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524 P F ++ V E+A +G + ++ A D D G +ITY L S E +F Sbjct: 1055 NNPYFVDSVNDYYVSENASVGAEIAIILAKDLDSGDFGRITYILDRVSSKE-------KF 1107 Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDG------GVPSLSDTTDVEISVVDVNDNE 578 I+P+ G + LDRE + Y+L V A D S + + I V+D NDN Sbjct: 1108 SIDPEKGILRVAGALDREETAEYMLAVEAWDNYPYGYLNGESRNAFKHILIHVLDDNDNV 1167 Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638 PV ++ + I E + + ++ ATDAD NG D D G F I S Sbjct: 1168 PVIQKPSGCSMITEYHNINDPIVKLRATDADDPTNGNGQLSFDIVD-PSGIFYIQQVSAQ 1226 Query: 639 IRT--NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF--ESDCLTF 694 ++ + + L+ + D G P ++ V I + D ND PVF S T Sbjct: 1227 YAEIYSRGPLKNLHGNYTLELIVSDLGGVPNTARETVDICVTDFNDHAPVFVVPSGNTTV 1286 Query: 695 YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN--SFSLETRQGSDKAELVTMV 752 + EN+ +G ++ A+D D G NA+V Y +K N FSL+ G EL Sbjct: 1287 KVFENTTLGKPFFQVHAYDEDVGENAIVRYRLKMDTMGNFRKFSLDKETG----ELSLAA 1342 Query: 753 DLDYESPRKKYELVIRA----ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCF 808 LD E + Y+L I A PL + V + + V DVNDN P +I N + Sbjct: 1343 SLDREQ-QMMYDLRIEAYDQGIPTPLSSTVDLIVYVRDVNDNLPQFLLKEISLNFTEHMT 1401 Query: 809 PVGPFGRVP-AYDADVTDKLQ--------YRILSGNNANLILLNETTGSMTLSPQLNTNV 859 P R+P D D D L Y I+ GN L+ + +T+ +L+ Sbjct: 1402 PGTERIRLPDTVDQDYLDPLDGPAASVVCYYIVHGNEDGHFGLDPVSHDLTVEKELDREK 1461 Query: 860 PKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDM 903 L + + T+ LS+ + L TV +ND+ Sbjct: 1462 KSLYKLHIKATEECTN----ANLSLDTTSHSGNLLKATVYINDI 1501 Score = 186 bits (454), Expect = 6e-45 Identities = 199/755 (26%), Positives = 327/755 (43%), Gaps = 85/755 (11%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72 V D ND+ P+F+ V E + G + TL+A D+D G +V Y I+ ++ + Sbjct: 160 VEDINDNEPIFKPFASVLEVAEDSPPGI-LTTLEAVDKDEGAYGQVVYYIQGLSEEN--- 215 Query: 73 EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSS 132 V + +G+ L RA LD E+ Y + V A D+A + R+++ Sbjct: 216 ------------NVFSISTSNGKGVVRLARA-LDYERQHFYHINVLAVDRA--IQGRINT 260 Query: 133 -TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV-----IAKIKATDADVGANSA 186 TA + V + D D P+F V + ED + ++ +KA D D G N+ Sbjct: 261 GTAALLVRVKDVEDQPPEFLVTQPVVRISEDAPIGTEVASMIYSLSTVKAVDGDRGINNR 320 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-------YRLVIRAQDGGSPSRSN 239 I Y I +++ F ID L G + + LD E + +V + P+ S+ Sbjct: 321 IIYGISNNGSEL-FEIDRLKGSLRTKQKLDREDSTNPINGAFILEVVAIEESKLQPAPSS 379 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRV------QAYDADEGVNAELT 293 T ++ + + DVND PRF + ++ + EN ++ R + +D D+G N Sbjct: 380 TMEITVIVTDVNDEIPRFRSDGYECEIGENAQEN-TLARFIDGSINEVFDYDQGKNGTFR 438 Query: 294 YTMTDKDYTGNVDLPITIDPRSGW--VYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 ++ V I+ + V LD E + L V A++ R++TA Sbjct: 439 LSLHPPSDIFEVIPKRAINEATFGLRVKDPSMLDYERVRELSLTVVASEVESAGRTSTAQ 498 Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE----DNRLHYEITGGN 407 F YE+++ E+ GT ++ L ATD+D + Y G+ Sbjct: 499 IRVVVLDQNDNFPEFSQPVYEIDVPENVTAGTVLLQLQATDSDSGLFGTEGVRYANLTGS 558 Query: 408 TRGRFSITSQNGRGLITVAQPLDFKQE--RRYVLTVSATDSGGRS--DTAMVQINITDAN 463 + G + ++ F +E +++ L+V A D+GGR +T + +N+ D N Sbjct: 559 ISSFLHLDPHAGTVTLMASESPVFDREIIQKHYLSVEARDNGGRGNRNTVPLILNVLDVN 618 Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV--GINAQITYSLSSEISNEAVAHHD 521 + APVF Y + E+A + +VV A DSD+ N+ + Y L AHH Sbjct: 619 DNAPVFVQKRYEVRLKENAFEFESPIVVEARDSDLEGSPNSAVEYRLIG-------AHHS 671 Query: 522 QQFVINPQTGAITTNKLLDRETM--SG-------YLLTVTARDGGVPSLSDTTDVEISVV 572 F ++ +TG ++ + +D E + SG LT+ A DGG P L+ +V + V Sbjct: 672 DYFHVDRRTGRLSVREAVDFERLESSGGSGDTRTIALTIEAADGGEPPLTAQVEVTVYVQ 731 Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL-NGRIHYELDPKDREEGSFV 631 DVND PVF + Y I ED G V +V A D D N + Y + + +G FV Sbjct: 732 DVNDYAPVFLESQYAIVIPEDTPSGLPVLRVTAMDGDGSFPNNHVTYRI--QQGGDGRFV 789 Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691 I ++G I S+ + L A+ G ST ++ + D + + C Sbjct: 790 IGASTGEISITHG---ASLDPNLLAPDALGSG-----STYVLEVFATDGGNGDQQLQGSC 841 Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 L N+P+GT + + A DPDEG A++ Y I Sbjct: 842 LV----NNTPVGTEVYRLMATDPDEG--AMLRYYI 870 Score = 179 bits (435), Expect = 1e-42 Identities = 171/634 (26%), Positives = 278/634 (43%), Gaps = 55/634 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I VLD ND++P F Y+ S+ E + G V T+ A D D +N V+Y++E Sbjct: 942 KITVLDENDNNPKFRKPFYKHSIAENSQYGVAVCTVVAEDAD--QNKTVKYSLE------ 993 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 V ++ +D +G ++ R +D E+ + V+A D +P Sbjct: 994 ------------GEKGVLELLHVDDETGEIVVRNRIDHEEYSWLNFSVRAADTGTPPR-- 1039 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 +S + V ++D+NDN P F + V E+ SV IA I A D D G I Y Sbjct: 1040 -ASFVEVFVQVLDENDNNPYFVDSVNDYYVSENASV--GAEIAIILAKDLDSGDFGRITY 1096 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG------GSPSRSNTTQL 243 + +++ +FSID G + + LD E+ Y L + A D SR+ + Sbjct: 1097 ILDRVSSKEKFSIDPEKGILRVAGALDREETAEYMLAVEAWDNYPYGYLNGESRNAFKHI 1156 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 LI++ D NDN P ++E I IV+++A DAD+ N + D +G Sbjct: 1157 LIHVLDDNDNVPVIQKPSGCSMITEYHNINDPIVKLRATDADDPTNGNGQLSFDIVDPSG 1216 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 + + + +Y+ G L + Y L + +D G P +A T Sbjct: 1217 IFYIQ-QVSAQYAEIYSRGPL-KNLHGNYTLELIVSDLGGVPNTARETVDICVTDFNDHA 1274 Query: 364 XXFM--PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEI---TGGNTRGRFSITS 416 F+ G V++ E+ G P + A D D E+ + Y + T GN R +FS+ Sbjct: 1275 PVFVVPSGNTTVKVFENTTLGKPFFQVHAYDEDVGENAIVRYRLKMDTMGNFR-KFSLDK 1333 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAP 473 + G +++A LD +Q+ Y L + A D G S T + + + D N+ P F Sbjct: 1334 ETGE--LSLAASLDREQQMMYDLRIEAYDQGIPTPLSSTVDLIVYVRDVNDNLPQFLLKE 1391 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 + + E GT + + T ++ + S + D F ++P + + Sbjct: 1392 ISLNFTEHMTPGTERIRLPDTVDQDYLDPLDGPAASVVCYYIVHGNEDGHFGLDPVSHDL 1451 Query: 534 TTNKLLDRETMSGYLLTVTARDGGV-PSLS-DTTD-------VEISVVDVNDNEPVFKQQ 584 T K LDRE S Y L + A + +LS DTT + + D+NDN PVF+ + Sbjct: 1452 TVEKELDREKKSLYKLHIKATEECTNANLSLDTTSHSGNLLKATVYINDINDNSPVFESK 1511 Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618 ++T I +L G ++ Q+ ATD D GLNG + Y Sbjct: 1512 IFTGGISTSSLFGATILQLQATDEDDGLNGLVRY 1545 Score = 175 bits (427), Expect = 1e-41 Identities = 169/633 (26%), Positives = 288/633 (45%), Gaps = 56/633 (8%) Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQLLINIRDVNDNAPRF 257 F ++ +G + + K LD E++ +L +D + + T L I + D NDN P+F Sbjct: 896 FILNETNGLLKIAKLLDREKIAEIKLACVVEDVAAERGDQMANTFLKITVLDENDNNPKF 955 Query: 258 YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317 ++ S++EN G ++ V A DAD+ N + Y++ + G ++L + +D +G Sbjct: 956 RKPFYKHSIAENSQYGVAVCTVVAEDADQ--NKTVKYSLEGEK--GVLEL-LHVDDETGE 1010 Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377 + ++D E + V A D G PPR++ F+ + ++E Sbjct: 1011 IVVRNRIDHEEYSWLNFSVRAADTGTPPRASFVEVFVQVLDENDNNPYFVDSVNDYYVSE 1070 Query: 378 DEPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435 + G + + A D D + R+ Y + +++ +FSI + +G++ VA LD ++ Sbjct: 1071 NASVGAEIAIILAKDLDSGDFGRITYILDRVSSKEKFSIDPE--KGILRVAGALDREETA 1128 Query: 436 RYVLTVSATDS------GGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 Y+L V A D+ G S A + I++ D N+ PV + + + E I Sbjct: 1129 EYMLAVEAWDNYPYGYLNGESRNAFKHILIHVLDDNDNVPVIQKPSGCSMITEYHNINDP 1188 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 ++ + ATD+D N LS +I + + + QQ ++ Q I + L + Y Sbjct: 1189 IVKLRATDADDPTNGN--GQLSFDIVDPSGIFYIQQ--VSAQYAEIYSRGPL-KNLHGNY 1243 Query: 548 LLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVF--KQQLYTANIMEDALVGTSVSQVG 604 L + D GGVP+ + T V+I V D ND+ PVF T + E+ +G QV Sbjct: 1244 TLELIVSDLGGVPNTARET-VDICVTDFNDHAPVFVVPSGNTTVKVFENTTLGKPFFQVH 1302 Query: 605 ATDADVGLNGRIHYELDPKDREE-GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 A D DVG N + Y L F +D +G + +LDRE +DL+ A D G Sbjct: 1303 AYDEDVGENAIVRYRLKMDTMGNFRKFSLDKETGELSLAASLDREQQMMYDLRIEAYDQG 1362 Query: 664 TP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT-------TIGEIRAHDPD 715 P P SSTV + + + D+ND+ P F ++ +E+ GT T+ + DP Sbjct: 1363 IPTPLSSTVDLIVYVRDVNDNLPQFLLKEISLNFTEHMTPGTERIRLPDTVDQDYL-DPL 1421 Query: 716 EGPNA-VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---- 770 +GP A VV Y I G++ F L+ +L +LD E + Y+L I+A Sbjct: 1422 DGPAASVVCYYIVHGNEDGHFGLDPVSH----DLTVEKELDREK-KSLYKLHIKATEECT 1476 Query: 771 --------SPPLWNDVRVEILVTDVNDNAPVMK 795 + N ++ + + D+NDN+PV + Sbjct: 1477 NANLSLDTTSHSGNLLKATVYINDINDNSPVFE 1509 Score = 175 bits (426), Expect = 1e-41 Identities = 191/692 (27%), Positives = 287/692 (41%), Gaps = 60/692 (8%) Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ-LLINIRDVNDNAPRFYTSLFQESVS 267 V L LD E Y L++ DG + TQ L+ + D+NDN P F V+ Sbjct: 121 VYLNHELDREAREEYTLILTLTDGRLGEGNFVTQSFLLLVEDINDNEPIFKPFASVLEVA 180 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 E+ P G + ++A D DEG ++ Y + NV I+ G V + LD E Sbjct: 181 EDSPPGI-LTTLEAVDKDEGAYGQVVYYIQGLSEENNV-FSISTSNGKGVVRLARALDYE 238 Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX--XFMPGQYEVELAEDEPPGTPV 385 Q Y + V A D R T T F+ Q V ++ED P GT V Sbjct: 239 RQHFYHINVLAVDRAIQGRINTGTAALLVRVKDVEDQPPEFLVTQPVVRISEDAPIGTEV 298 Query: 386 V-------TLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436 T+ A D D +NR+ Y I+ + F I +G + Q LD + Sbjct: 299 ASMIYSLSTVKAVDGDRGINNRIIYGISNNGSE-LFEIDRL--KGSLRTKQKLDREDSTN 355 Query: 437 -----YVLTVSATDSG----GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 ++L V A + S T + + +TD N+ P F + Y + E+A T Sbjct: 356 PINGAFILEVVAIEESKLQPAPSSTMEITVIVTDVNDEIPRFRSDGYECEIGENAQENTL 415 Query: 488 VLVVSAT-----DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA-ITTNKLLDR 541 + + D D G N T+ LS ++ ++ + G + +LD Sbjct: 416 ARFIDGSINEVFDYDQGKNG--TFRLSLHPPSDIFEVIPKRAINEATFGLRVKDPSMLDY 473 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 E + LTV A + + T + + V+D NDN P F Q +Y ++ E+ GT + Sbjct: 474 ERVRELSLTVVASEVESAGRTSTAQIRVVVLDQNDNFPEFSQPVYEIDVPENVTAGTVLL 533 Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFV-IDPASGVI----RTNKALDRESVATHDLK 656 Q+ ATD+D GL G SF+ +DP +G + + DRE + H L Sbjct: 534 QLQATDSDSGLFGTEGVRYANLTGSISSFLHLDPHAGTVTLMASESPVFDREIIQKHYLS 593 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN-----SPIGTTIGEIRA 711 A D G +TV + + + D+ND+ PVF + EN SPI + E R Sbjct: 594 VEARDNGGRGNRNTVPLILNVLDVNDNAPVFVQKRYEVRLKENAFEFESPI---VVEARD 650 Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS-DKAELVTMVDLDY---ESPRKKYELVI 767 D + PN+ V Y + G S+ F ++ R G E V L+ + L I Sbjct: 651 SDLEGSPNSAVEYRLIGAHHSDYFHVDRRTGRLSVREAVDFERLESSGGSGDTRTIALTI 710 Query: 768 RAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD- 822 AA PPL V V + V DVND APV + Q +D P G P RV A D D Sbjct: 711 EAADGGEPPLTAQVEVTVYVQDVNDYAPVFLESQYAIVIPEDT-PSGLPVLRVTAMDGDG 769 Query: 823 --VTDKLQYRILSGNNANLILLNETTGSMTLS 852 + + YRI G + + + +TG ++++ Sbjct: 770 SFPNNHVTYRIQQGGDGRFV-IGASTGEISIT 800 Score = 167 bits (407), Expect = 3e-39 Identities = 171/621 (27%), Positives = 274/621 (44%), Gaps = 53/621 (8%) Query: 271 PIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA 330 P+G I R++ YDAD LT+ + + + L + +VY + +LDRE + Sbjct: 78 PVGTLIYRLRGYDAD---GDPLTFGVQKSADSHIIRLKQNTSSEA-FVYLNHELDREARE 133 Query: 331 KYQLLVTATDGG-DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389 +Y L++T TDG T + F P +E+AED PPG + TL Sbjct: 134 EYTLILTLTDGRLGEGNFVTQSFLLLVEDINDNEPIFKPFASVLEVAEDSPPGI-LTTLE 192 Query: 390 ATDADED--NRLHYEITG-GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446 A D DE ++ Y I G FSI++ NG+G++ +A+ LD++++ Y + V A D Sbjct: 193 AVDKDEGAYGQVVYYIQGLSEENNVFSISTSNGKGVVRLARALDYERQHFYHINVLAVDR 252 Query: 447 G--GR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL-------VVSATD 495 GR + TA + + + D + P F + EDAPIGT V V A D Sbjct: 253 AIQGRINTGTAALLVRVKDVEDQPPEFLVTQPVVRISEDAPIGTEVASMIYSLSTVKAVD 312 Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS-----GYLLT 550 D GIN +I Y +S+ S + F I+ G++ T + LDRE + ++L Sbjct: 313 GDRGINNRIIYGISNNGS--------ELFEIDRLKGSLRTKQKLDREDSTNPINGAFILE 364 Query: 551 VTARDGG--VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT-- 606 V A + P+ S T ++ + V DVND P F+ Y I E+A T + + Sbjct: 365 VVAIEESKLQPAPSSTMEITVIVTDVNDEIPRFRSDGYECEIGENAQENTLARFIDGSIN 424 Query: 607 ---DADVGLNGRIHYEL-DPKDREE--GSFVIDPASGVIRTN--KALDRESVATHDLKAV 658 D D G NG L P D E I+ A+ +R LD E V L V Sbjct: 425 EVFDYDQGKNGTFRLSLHPPSDIFEVIPKRAINEATFGLRVKDPSMLDYERVRELSLTVV 484 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG- 717 A + + ++ST + + + D ND+ P F + EN GT + +++A D D G Sbjct: 485 ASEVESAGRTSTAQIRVVVLDQNDNFPEFSQPVYEIDVPENVTAGTVLLQLQATDSDSGL 544 Query: 718 -PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN 776 V Y+ G S+ L+ G+ D E +K Y V + N Sbjct: 545 FGTEGVRYANLTGSISSFLHLDPHAGTVTLMASESPVFDREIIQKHYLSVEARDNGGRGN 604 Query: 777 DVRVEIL--VTDVNDNAP--VMKDFQIIF--NNYKDCFPVGPFGRVPAYDADVTDKLQYR 830 V ++ V DVNDNAP V K +++ N ++ P+ R + ++YR Sbjct: 605 RNTVPLILNVLDVNDNAPVFVQKRYEVRLKENAFEFESPIVVEARDSDLEGSPNSAVEYR 664 Query: 831 ILSGNNANLILLNETTGSMTL 851 ++ ++++ ++ TG +++ Sbjct: 665 LIGAHHSDYFHVDRRTGRLSV 685 Score = 151 bits (367), Expect = 2e-34 Identities = 158/588 (26%), Positives = 251/588 (42%), Gaps = 79/588 (13%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND++P F + V E AS G + + A D D G + Y ++ V++ Sbjct: 1047 VQVLDENDNNPYFVDSVNDYYVSENASVGAEIAIILAKDLDSGDFGRITYILDRVSS--- 1103 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS-PVSDR 129 ++ F ID G L +LDRE+ A Y + V+A D + Sbjct: 1104 ----------------KEKFSIDPEKGILRVAGALDREETAEYMLAVEAWDNYPYGYLNG 1147 Query: 130 LSSTATIHV--NIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 S A H+ +++DDNDN P + + + E ++ D P++ K++ATDAD N Sbjct: 1148 ESRNAFKHILIHVLDDNDNVPVIQKPSGCSMITEYHNIND-PIV-KLRATDADDPTN--- 1202 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVK-TLDYEQVRS----------YRLVIRAQD-GGSP 235 GN Q+ F I SG + + + Y ++ S Y L + D GG P Sbjct: 1203 ------GNGQLSFDIVDPSGIFYIQQVSAQYAEIYSRGPLKNLHGNYTLELIVSDLGGVP 1256 Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVS--ENVPIGYSIVRVQAYDADEGVNAELT 293 + + T + I + D ND+AP F +V EN +G +V AYD D G NA + Sbjct: 1257 NTARET-VDICVTDFNDHAPVFVVPSGNTTVKVFENTTLGKPFFQVHAYDEDVGENAIVR 1315 Query: 294 YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSATATX 352 Y + D GN ++D +G + + LDRE Q Y L + A D G P P S+T Sbjct: 1316 YRLK-MDTMGNFR-KFSLDKETGELSLAASLDREQQMMYDLRIEAYDQGIPTPLSSTVDL 1373 Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTAT---------DADEDNRLHYEI 403 F+ + + E PGT + L T D + + Y I Sbjct: 1374 IVYVRDVNDNLPQFLLKEISLNFTEHMTPGTERIRLPDTVDQDYLDPLDGPAASVVCYYI 1433 Query: 404 TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM--------- 454 GN G F + + +TV + LD +++ Y L + AT+ ++ ++ Sbjct: 1434 VHGNEDGHFGLDPVSHD--LTVEKELDREKKSLYKLHIKATEECTNANLSLDTTSHSGNL 1491 Query: 455 --VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512 + I D N+ +PVFE+ +T + + G T+L + ATD D G+N + Y E+ Sbjct: 1492 LKATVYINDINDNSPVFESKIFTGGISTSSLFGATILQLQATDEDDGLNGLVRYYRHGEV 1551 Query: 513 SNEAVAHHD----QQFVINPQTGAITTNKLLDRETMSGYL-LTVTARD 555 D F++ TG + N +++M GY +V A D Sbjct: 1552 RKTLAEGLDDLRSDPFLVEADTGQVLLN-FFPQKSMRGYFDFSVLAND 1598 Score = 44.4 bits (100), Expect = 0.046 Identities = 36/127 (28%), Positives = 61/127 (48%), Gaps = 10/127 (7%) Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759 +P+GT I +R +D D P + + ++ DS+ L+ + S +A + +LD E+ Sbjct: 77 TPVGTLIYRLRGYDADGDP---LTFGVQKSADSHIIRLK-QNTSSEAFVYLNHELDREA- 131 Query: 760 RKKYELVIRAASPPLWNDVRVE----ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR 815 R++Y L++ L V +LV D+NDN P+ K F + +D P G Sbjct: 132 REEYTLILTLTDGRLGEGNFVTQSFLLLVEDINDNEPIFKPFASVLEVAEDS-PPGILTT 190 Query: 816 VPAYDAD 822 + A D D Sbjct: 191 LEAVDKD 197 >UniRef50_Q9VGG5 Cluster: Cadherin 87A precursor; n=2; Diptera|Rep: Cadherin 87A precursor - Drosophila melanogaster (Fruit fly) Length = 1975 Score = 254 bits (621), Expect = 3e-65 Identities = 230/775 (29%), Positives = 349/775 (45%), Gaps = 79/775 (10%) Query: 11 INVLDCNDHSPVFEMQQYEAS----VREGASSG-TTVLTLKATDQDIGKNAEVEYTIELV 65 I++ +C+D+ ++ + + V E G +L+++A ++IG V+YT L+ Sbjct: 530 ISLANCHDNGESNRRERRDLNEDEHVEEDDGEGHLEMLSMEAATREIGTEPTVQYT--LI 587 Query: 66 TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125 T + + + LD E Y + KATD Sbjct: 588 TQAPEEQASSVPLPAPVPHAAPSGVPAATANDDKAPQTCLDYESETTYFLSYKATDDNGR 647 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 S +S ++ +++ D ND+ P Y SVDE V D+P+I +KA DAD S Sbjct: 648 GS---ASVVSLRISVTDANDSPPVCESPLYRASVDEGAVVFDSPLI--VKARDADT--MS 700 Query: 186 AIRYAIIGGN-TQMQFSIDSLSGDVSLVK--TLDYEQVRSYRLV--IRAQDGGSPSRSNT 240 I Y I G + F ID +G + + TLD + S +L+ + A DG + Sbjct: 701 RISYRIRGSEQVESIFDIDRETGQIIIRPNATLDVTNLNSDQLIFAVEANDGLFTAHCGV 760 Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 I +RDVN++ P F + V EN IG S+ RV A D D G NAEL Y + Sbjct: 761 N---ITVRDVNNHVPNFEQQSYSAVVEENSEIGTSVERVHATDLDTGKNAELRYRIQQ-- 815 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 G+ D I +G V+ S +LD + + YQL + A+D G P + TAT Sbjct: 816 --GSFD-DFGIVETTGEVFVSRKLDFDRRNTYQLQIQASDQGTPSLTGTATLTINVQNSN 872 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHY----EITGGNTRGR--- 411 F+P E+ D PPG V TL A D D N L + +IT + G+ Sbjct: 873 DKDPYFVPATQHAEVRADAPPGQLVYTLIALDPDVANHNALEFAGTDDITAIDKEGKELP 932 Query: 412 --------FSITSQNGRGLITVAQPLD---FKQERRYVLTVSATDSGGRSDTAMVQINIT 460 F I S+NG+ ++V + LD F R VL +T + ++ I I Sbjct: 933 HYDQFKEYFKI-SRNGK--VSVNKQLDRNLFAVMRINVLVTDSTAPNVQQGRGLLIIQII 989 Query: 461 DANNYAPVFENAPYTAS-------VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513 D N P F NAP++ + E+ P+GT + + A D D S I Sbjct: 990 DVNKNPPRF-NAPWSVEQPQIKLQMVEEQPVGTVLTTLQANDED------------SSIG 1036 Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 ++ +D F IN +G I T LD E + VT D GVP+L+ T DV + +++ Sbjct: 1037 EFNISDNDY-FAINQTSGMIYTIARLDYEVVKEVKFQVTVSDTGVPALTATADVVVDIIN 1095 Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633 +NDN+P F Q Y N+ E++ GT +V A D DVG+ G I Y L ++ + F ID Sbjct: 1096 LNDNDPKFSQSDYYFNVTENSPRGTVAGKVEAHDGDVGVFGEITYTLIGENNK--YFSID 1153 Query: 634 PASG--VIRTNKALDRESVATHDLKAVAID--GGTPPQSSTVIVHIKIEDINDSPPVFES 689 +G ++ + LDRE + L VA D +S+T +HI I D+ND+ PVF Sbjct: 1154 AYTGNVMVANSSILDREQIKELTLSVVAQDKAPAAVQKSATATIHINILDVNDNAPVFTR 1213 Query: 690 DCLTFYISENSPI--GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 D ++EN+ + +++A D DEG V Y I G++ F L+ + G Sbjct: 1214 DVYNSTVAENAAYQPPAALLQVQAIDQDEGLYGDVRYIITAGNEMGLFKLDAQSG 1268 Score = 242 bits (593), Expect = 8e-62 Identities = 255/901 (28%), Positives = 398/901 (44%), Gaps = 107/901 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D N+H P FE Q Y A V E + GT+V + ATD D GKNAE+ Y I+ + D Sbjct: 762 ITVRDVNNHVPNFEQQSYSAVVEENSEIGTSVERVHATDLDTGKNAELRYRIQQGSFDD- 820 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F I +G + LD ++ Y + ++A+DQ +P L Sbjct: 821 -------------------FGIVETTGEVFVSRKLDFDRRNTYQLQIQASDQGTP---SL 858 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + TAT+ +N+ + ND P F T V D ++ + A D DV ++A+ +A Sbjct: 859 TGTATLTINVQNSNDKDPYFVPATQHAEVRAD--APPGQLVYTLIALDPDVANHNALEFA 916 Query: 191 IIGGNTQMQ---------------FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP 235 T + F I S +G VS+ K LD R+ + D +P Sbjct: 917 GTDDITAIDKEGKELPHYDQFKEYFKI-SRNGKVSVNKQLDRNLFAVMRINVLVTDSTAP 975 Query: 236 S-RSNTTQLLINIRDVNDNAPRFYT--SLFQESVS----ENVPIGYSIVRVQAYDADEGV 288 + + L+I I DVN N PRF S+ Q + E P+G + +QA D D + Sbjct: 976 NVQQGRGLLIIQIIDVNKNPPRFNAPWSVEQPQIKLQMVEEQPVGTVLTTLQANDEDSSI 1035 Query: 289 NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348 + ++D DY I+ SG +YT +LD E + + VT +D G P +A Sbjct: 1036 GE---FNISDNDY-------FAINQTSGMIYTIARLDYEVVKEVKFQVTVSDTGVPALTA 1085 Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGG 406 TA F Y + E+ P GT + A D D + Y + G Sbjct: 1086 TADVVVDIINLNDNDPKFSQSDYYFNVTENSPRGTVAGKVEAHDGDVGVFGEITYTLIGE 1145 Query: 407 NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG----RSDTAMVQINITDA 462 N + FSI + G ++ + LD +Q + L+V A D +S TA + INI D Sbjct: 1146 NNK-YFSIDAYTGNVMVANSSILDREQIKELTLSVVAQDKAPAAVQKSATATIHINILDV 1204 Query: 463 NNYAPVFENAPYTASVFEDAPIG--TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520 N+ APVF Y ++V E+A +L V A D D G+ + Y +++ NE Sbjct: 1205 NDNAPVFTRDVYNSTVAENAAYQPPAALLQVQAIDQDEGLYGDVRYIITA--GNEMGL-- 1260 Query: 521 DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEP 579 F ++ Q+G + + L + Y LT++ARD G ++ TT I+V+ VN ++P Sbjct: 1261 ---FKLDAQSGIVYPAQSLSGKH-GAYELTISARDTQGSGTMESTTKAIITVLRVNRHKP 1316 Query: 580 VFK-QQLYTANI-MEDALVGTS--VSQVGATDADVGLNGRIHYELDPKDREE---GSFVI 632 F L A I + +V + V A D D NG++ Y L +R E G F I Sbjct: 1317 EFVIPALSNATIEIPGDIVQPDYLLLTVRAMDNDTEENGKVSYHLQVNNRNEQQTGEFKI 1376 Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF--ESD 690 D +G +R L+R++ A +D+ VA D G PP S ++ + I D N++ P F S+ Sbjct: 1377 DEVTGELRAKTQLNRKNRANYDIILVARDAGNPPFESLRLLSVSIVDANENRPEFPDASN 1436 Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF------SLETRQGSD 744 I+ENS IG I+A + + +Y + G +D + + T + D Sbjct: 1437 PYKVSINENSGRDVKIGHIQAASRSKHNRDIFYYMLLGNEDGAFYVDKLTGDIYTNKSLD 1496 Query: 745 KAE-------LVTMVDLD-YESPRKKYELVIRAASPPLWNDV-RVEILVTDVNDNAPVMK 795 + E ++ + D + S ++ I+ + N V +V I V DVNDN PV + Sbjct: 1497 REETDVYTLYILASIKADLHISEEERASFSIKTLNRD--NTVAKVAITVLDVNDNPPVFE 1554 Query: 796 DFQIIFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLS 852 I + +G V A DAD K+++ I++ +N ++TGS+ S Sbjct: 1555 K-PIYYAGVNANAKMGAAITLVNATDADQGKNAKIEFMIVA-SNLYKFGATKSTGSIVPS 1612 Query: 853 P 853 P Sbjct: 1613 P 1613 Score = 223 bits (546), Expect = 4e-56 Identities = 237/901 (26%), Positives = 409/901 (45%), Gaps = 92/901 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I+V D ND PV E Y ASV EGA + L +KA D D + + Y I Sbjct: 656 RISVTDANDSPPVCESPLYRASVDEGAVVFDSPLIVKARDADT--MSRISYRIR------ 707 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR--ASLDREKVARYTVLVKATDQASPVS 127 V+ +F ID +G ++ R A+LD + ++ A + Sbjct: 708 ------------GSEQVESIFDIDRETGQIIIRPNATLDVTNLNSDQLIF-----AVEAN 750 Query: 128 DRL-SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 D L ++ +++ + D N++ P F +++Y+ V+E+ + + + ++ ATD D G N+ Sbjct: 751 DGLFTAHCGVNITVRDVNNHVPNFEQQSYSAVVEENSEIGTS--VERVHATDLDTGKNAE 808 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 +RY I G+ F I +G+V + + LD+++ +Y+L I+A D G+PS + T L IN Sbjct: 809 LRYRIQQGSFD-DFGIVETTGEVFVSRKLDFDRRNTYQLQIQASDQGTPSLTGTATLTIN 867 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK----DYT 302 +++ ND P F + V + P G + + A D D + L + TD D Sbjct: 868 VQNSNDKDPYFVPATQHAEVRADAPPGQLVYTLIALDPDVANHNALEFAGTDDITAIDKE 927 Query: 303 GNVDLPITID-------PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP-RSATATXXX 354 G +LP R+G V + QLDR A ++ V TD P + Sbjct: 928 GK-ELPHYDQFKEYFKISRNGKVSVNKQLDRNLFAVMRINVLVTDSTAPNVQQGRGLLII 986 Query: 355 XXXXXXXXXXXFMPG------QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT 408 F Q ++++ E++P GT + TL A D D + I+ + Sbjct: 987 QIIDVNKNPPRFNAPWSVEQPQIKLQMVEEQPVGTVLTTLQANDEDSSIG-EFNISDNDY 1045 Query: 409 RGRFSITSQNGRGLITVAQPLDFK--QERRYVLTVSATDSGGRSDTAMVQINITDANNYA 466 F+I +G + T+A+ LD++ +E ++ +TVS T + TA V ++I + N+ Sbjct: 1046 ---FAINQTSGM-IYTIAR-LDYEVVKEVKFQVTVSDTGVPALTATADVVVDIINLNDND 1100 Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 P F + Y +V E++P GT V A D DVG+ +ITY+L E +++ F I Sbjct: 1101 PKFSQSDYYFNVTENSPRGTVAGKVEAHDGDVGVFGEITYTLIGE--------NNKYFSI 1152 Query: 527 NPQTG--AITTNKLLDRETMSGYLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFK 582 + TG + + +LDRE + L+V A+D ++ S T + I+++DVNDN PVF Sbjct: 1153 DAYTGNVMVANSSILDREQIKELTLSVVAQDKAPAAVQKSATATIHINILDVNDNAPVFT 1212 Query: 583 QQLYTANIMEDALVG--TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640 + +Y + + E+A ++ QV A D D GL G + Y + + E G F +D SG++ Sbjct: 1213 RDVYNSTVAENAAYQPPAALLQVQAIDQDEGLYGDVRYIITAGN-EMGLFKLDAQSGIVY 1271 Query: 641 TNKALDRESVATHDLKAVAIDG-GTPPQSSTVIVHIKIEDINDSPPVFESDCL---TFYI 696 ++L + A ++L A D G+ ST I + +N P F L T I Sbjct: 1272 PAQSLSGKHGA-YELTISARDTQGSGTMESTTKAIITVLRVNRHKPEFVIPALSNATIEI 1330 Query: 697 -SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755 + + +RA D D N V Y ++ + + + E + EL L+ Sbjct: 1331 PGDIVQPDYLLLTVRAMDNDTEENGKVSYHLQVNNRNEQQTGEFKIDEVTGELRAKTQLN 1390 Query: 756 YESPRKKYELVI--RAASPPLWNDVRV-EILVTDVNDNAPVMKDFQIIFNNYKDCFPVG- 811 ++ R Y++++ R A P + +R+ + + D N+N P +F N YK Sbjct: 1391 RKN-RANYDIILVARDAGNPPFESLRLLSVSIVDANENRP---EFPDASNPYKVSINENS 1446 Query: 812 ----PFGRVPAYDADVTDK-LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATME 866 G + A ++ + Y +L GN +++ TG + + L+ + T+ Sbjct: 1447 GRDVKIGHIQAASRSKHNRDIFYYMLLGNEDGAFYVDKLTGDIYTNKSLDREETDVYTLY 1506 Query: 867 V 867 + Sbjct: 1507 I 1507 Score = 198 bits (484), Expect = 1e-48 Identities = 194/659 (29%), Positives = 298/659 (45%), Gaps = 69/659 (10%) Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 TL D D F I+ SG + T A LD E V V +D P Sbjct: 1025 TLQANDEDSSIGEFNISDNDYFAINQTSGMIYTIARLDYEVVKEVKFQVTVSDTGVPA-- 1082 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 L++TA + V+II+ NDN P+FS+ Y +V E+ V K++A D DVG I Sbjct: 1083 -LTATADVVVDIINLNDNDPKFSQSDYYFNVTENSP--RGTVAGKVEAHDGDVGVFGEIT 1139 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPS--RSNTTQLL 244 Y +IG N + FSID+ +G+V + + LD EQ++ L + AQD + +S T + Sbjct: 1140 YTLIGENNKY-FSIDAYTGNVMVANSSILDREQIKELTLSVVAQDKAPAAVQKSATATIH 1198 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIG--YSIVRVQAYDADEGVNAELTYTMTDKDYT 302 INI DVNDNAP F ++ +V+EN ++++VQA D DEG+ ++ Y +T Sbjct: 1199 INILDVNDNAPVFTRDVYNSTVAENAAYQPPAALLQVQAIDQDEGLYGDVRYIIT----A 1254 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD--GGDPPRSATATXXXXXXXXX 360 GN +D +SG VY + L + A Y+L ++A D G S T Sbjct: 1255 GNEMGLFKLDAQSGIVYPAQSLSGKHGA-YELTISARDTQGSGTMESTTKAIITVLRVNR 1313 Query: 361 XXXXXFMPG--QYEVELAED-EPPGTPVVTLTATDAD--EDNRLHYEITGGNTR----GR 411 +P +E+ D P ++T+ A D D E+ ++ Y + N G Sbjct: 1314 HKPEFVIPALSNATIEIPGDIVQPDYLLLTVRAMDNDTEENGKVSYHLQVNNRNEQQTGE 1373 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVF 469 F I G + L+ K Y + + A D+G ++ ++I DAN P F Sbjct: 1374 FKIDEVTGE--LRAKTQLNRKNRANYDIILVARDAGNPPFESLRLLSVSIVDANENRPEF 1431 Query: 470 ENA--PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527 +A PY S+ E++ + + A N I Y + + NE D F ++ Sbjct: 1432 PDASNPYKVSINENSGRDVKIGHIQAASRSKH-NRDIFYYML--LGNE-----DGAFYVD 1483 Query: 528 PQTGAITTNKLLDRETMSGYLLTVTAR-------------DGGVPSLS-DTT--DVEISV 571 TG I TNK LDRE Y L + A + +L+ D T V I+V Sbjct: 1484 KLTGDIYTNKSLDREETDVYTLYILASIKADLHISEEERASFSIKTLNRDNTVAKVAITV 1543 Query: 572 VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD------- 624 +DVNDN PVF++ +Y A + +A +G +++ V ATDAD G N +I + + + Sbjct: 1544 LDVNDNPPVFEKPIYYAGVNANAKMGAAITLVNATDADQGKNAKIEFMIVASNLYKFGAT 1603 Query: 625 REEGSFVIDP----ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679 + GS V P G I N + + +L+ VA + P S++ V+I + D Sbjct: 1604 KSTGSIVPSPFAISQDGRISANTIMAEYNQDRFELEIVARELEQPQSSASTKVNIWVFD 1662 Score = 187 bits (455), Expect = 4e-45 Identities = 213/808 (26%), Positives = 344/808 (42%), Gaps = 81/808 (10%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVL-TLKATDQDI-GKNAEVEYTIELVTADTL 70 +LD ND+ P F+ YEA V E A+ GTT+ + D+DI G++ +++ Sbjct: 122 ILDLNDNPPEFQNTPYEADVNEDAAVGTTIFDKITVKDRDIVGESLDLK-----CLPQQQ 176 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +PE + A++ +L+ + Y ++ATD Sbjct: 177 SPEACRKFRLHIIKRDATIL-----EAAVVLNDTLNYNQRMVYHFQIEATDGPH------ 225 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + T + D D P F TV +DED + N ++ + A D D G I Y Sbjct: 226 KTQTTFEARVKDVQDKPPVFQGSLSTV-IDEDSPI--NTLVLTVHARDGDTGEPRKIVYD 282 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS----YRLVIRAQD--GGSPS----RSNT 240 + N F +D+ +G++ K LD E + LVIRA++ G PS S T Sbjct: 283 -LRTNPNDYFLLDAQTGELRTAKPLDREALEDSTGIISLVIRARELVNGVPSDDPLTSAT 341 Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSI-VRVQAYDADEGVNAELTYTMTDK 299 + + IRDVND+ P F + S+ EN G + + + DAD G+N++ + D Sbjct: 342 AKATVTIRDVNDSPPVFNHKEYSVSLLENTLPGTPLALDMSVSDADVGINSKFALRLDDV 401 Query: 300 DYTGNVDLP-ITIDPRSGWVYTSGQLDRE--TQAKYQLLVTATDGGDPPR-SATATXXXX 355 +V+ +T + +G LD E Q K+ +LV A + PR S+TAT Sbjct: 402 SGVFDVEPKLVTGYSQVNIRVANGTLDYENPNQRKFIVLVVAEETDTNPRLSSTATITVS 461 Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE----DNRLHYEITGGNTRGR 411 F Y ++E PG + T+TA D D D+ + Y ++G Sbjct: 462 VLDANDNKPVFEQESYSASVSEAALPGQYIATITARDVDSGSYGDSGIRYSLSGTGAE-L 520 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN 471 F + Q G+I++A D + R D D D + + Sbjct: 521 FHVNEQT--GVISLANCHDNGESNRRERRDLNEDEHVEED---------DGEGHLEMLSM 569 Query: 472 APYTASVFEDAPIGTTVLVVSATD--SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 T + + + T++ + + S V + A + ++ S + A A+ D+ PQ Sbjct: 570 EAATREIGTEPTVQYTLITQAPEEQASSVPLPAPVPHAAPSGVP-AATANDDKA----PQ 624 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589 T LD E+ + Y L+ A D + + ISV D ND+ PV + LY A+ Sbjct: 625 T-------CLDYESETTYFLSYKATDDNGRGSASVVSLRISVTDANDSPPVCESPLYRAS 677 Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG--VIRTNKALDR 647 + E A+V S V A DAD RI Y + ++ E F ID +G +IR N LD Sbjct: 678 VDEGAVVFDSPLIVKARDADT--MSRISYRIRGSEQVESIFDIDRETGQIIIRPNATLDV 735 Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 ++ + L A++ ++ V+I + D+N+ P FE + + ENS IGT++ Sbjct: 736 TNLNSDQL-IFAVEANDGLFTAHCGVNITVRDVNNHVPNFEQQSYSAVVEENSEIGTSVE 794 Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 + A D D G NA + Y I+ G + +ET E+ LD++ R Y+L I Sbjct: 795 RVHATDLDTGKNAELRYRIQQGSFDDFGIVET-----TGEVFVSRKLDFDR-RNTYQLQI 848 Query: 768 RAA---SPPLWNDVRVEILVTDVNDNAP 792 +A+ +P L + I V + ND P Sbjct: 849 QASDQGTPSLTGTATLTINVQNSNDKDP 876 Score = 185 bits (450), Expect = 2e-44 Identities = 172/659 (26%), Positives = 289/659 (43%), Gaps = 43/659 (6%) Query: 215 LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY 274 LDYE +Y L +A D ++ L I++ D ND+ P + L++ SV E + Sbjct: 627 LDYESETTYFLSYKATDDNGRGSASVVSLRISVTDANDSPPVCESPLYRASVDEGAVVFD 686 Query: 275 SIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE-TQAKYQ 333 S + V+A DAD + ++Y + + ++ ID +G + + T Sbjct: 687 SPLIVKARDAD--TMSRISYRIRGSEQVESI---FDIDRETGQIIIRPNATLDVTNLNSD 741 Query: 334 LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393 L+ A + D +A F Y + E+ GT V + ATD Sbjct: 742 QLIFAVEANDGLFTAHCGVNITVRDVNNHVPNFEQQSYSAVVEENSEIGTSVERVHATDL 801 Query: 394 D--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS- 450 D ++ L Y I G+ F I G + V++ LDF + Y L + A+D G S Sbjct: 802 DTGKNAELRYRIQQGSFDD-FGIVETTGE--VFVSRKLDFDRRNTYQLQIQASDQGTPSL 858 Query: 451 -DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509 TA + IN+ ++N+ P F A A V DAP G V + A D DV + + ++ + Sbjct: 859 TGTATLTINVQNSNDKDPYFVPATQHAEVRADAPPGQLVYTLIALDPDVANHNALEFAGT 918 Query: 510 SEIS-----NEAVAHHDQ--QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 +I+ + + H+DQ ++ + G ++ NK LDR + + V D P++ Sbjct: 919 DDITAIDKEGKELPHYDQFKEYFKISRNGKVSVNKQLDRNLFAVMRINVLVTDSTAPNVQ 978 Query: 563 DTTDVEI-SVVDVNDNEPVF------KQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615 + I ++DVN N P F +Q ++E+ VGT ++ + A D D + Sbjct: 979 QGRGLLIIQIIDVNKNPPRFNAPWSVEQPQIKLQMVEEQPVGTVLTTLQANDEDSSIG-- 1036 Query: 616 IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675 E + D + F I+ SG+I T LD E V + D G P ++T V + Sbjct: 1037 ---EFNISDNDY--FAINQTSGMIYTIARLDYEVVKEVKFQVTVSDTGVPALTATADVVV 1091 Query: 676 KIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735 I ++ND+ P F F ++ENSP GT G++ AHD D G + Y++ G +++ F Sbjct: 1092 DIINLNDNDPKFSQSDYYFNVTENSPRGTVAGKVEAHDGDVGVFGEITYTLIG-ENNKYF 1150 Query: 736 SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND---VRVEILVTDVNDNAP 792 S++ G+ +++D + + +V + +P + I + DVNDNAP Sbjct: 1151 SIDAYTGNVMVANSSILDRE-QIKELTLSVVAQDKAPAAVQKSATATIHINILDVNDNAP 1209 Query: 793 VM-KD-FQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTG 847 V +D + P +V A D D + ++Y I +GN L L+ +G Sbjct: 1210 VFTRDVYNSTVAENAAYQPPAALLQVQAIDQDEGLYGDVRYIITAGNEMGLFKLDAQSG 1268 Score = 184 bits (449), Expect = 2e-44 Identities = 160/596 (26%), Positives = 262/596 (43%), Gaps = 57/596 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +++++ ND+ P F Y +V E + GT ++A D D+G E+ YT+ Sbjct: 1091 VDIINLNDNDPKFSQSDYYFNVTENSPRGTVAGKVEAHDGDVGVFGEITYTL-------- 1142 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS--LDREKVARYTVLVKATDQASPVSD 128 F ID +G ++ S LDRE++ T+ V A D+A P + Sbjct: 1143 ------------IGENNKYFSIDAYTGNVMVANSSILDREQIKELTLSVVAQDKA-PAAV 1189 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 + S+TATIH+NI+D NDN P F+ Y +V E+ + + +++A D D G +R Sbjct: 1190 QKSATATIHINILDVNDNAPVFTRDVYNSTVAENAAYQPPAALLQVQAIDQDEGLYGDVR 1249 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG-GSPSRSNTTQLLINI 247 Y I GN F +D+ SG V ++L + +Y L I A+D GS + +TT+ +I + Sbjct: 1250 YIITAGNEMGLFKLDAQSGIVYPAQSLSGKH-GAYELTISARDTQGSGTMESTTKAIITV 1308 Query: 248 RDVNDNAPRFYTSLFQESVSEN----VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 VN + P F + E V Y ++ V+A D D N +++Y + + Sbjct: 1309 LRVNRHKPEFVIPALSNATIEIPGDIVQPDYLLLTVRAMDNDTEENGKVSYHLQVNNRNE 1368 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 ID +G + QL+R+ +A Y +++ A D G+PP + Sbjct: 1369 QQTGEFKIDEVTGELRAKTQLNRKNRANYDIILVARDAGNPPFESLRLLSVSIVDANENR 1428 Query: 364 XXFMPGQ--YEVELAEDEPPGTPVVTLTATDADEDNR-LHYEITGGNTRGRFSITSQNGR 420 F Y+V + E+ + + A + NR + Y + GN G F + G Sbjct: 1429 PEFPDASNPYKVSINENSGRDVKIGHIQAASRSKHNRDIFYYMLLGNEDGAFYVDKLTGD 1488 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSG-----------------GRSDT-AMVQINITDA 462 I + LD ++ Y L + A+ R +T A V I + D Sbjct: 1489 --IYTNKSLDREETDVYTLYILASIKADLHISEEERASFSIKTLNRDNTVAKVAITVLDV 1546 Query: 463 NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL-SSEISNEAVAHHD 521 N+ PVFE Y A V +A +G + +V+ATD+D G NA+I + + +S + Sbjct: 1547 NDNPPVFEKPIYYAGVNANAKMGAAITLVNATDADQGKNAKIEFMIVASNLYKFGATKST 1606 Query: 522 QQFVINP----QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 V +P Q G I+ N ++ + L + AR+ P S +T V I V D Sbjct: 1607 GSIVPSPFAISQDGRISANTIMAEYNQDRFELEIVARELEQPQSSASTKVNIWVFD 1662 Score = 146 bits (353), Expect = 1e-32 Identities = 149/513 (29%), Positives = 232/513 (45%), Gaps = 50/513 (9%) Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434 L E+ GT V L A D E + + Y G + FS+ +G IT+ +PLD +++ Sbjct: 36 LYENVTVGTVVFRLEAYDP-EGSPVTYGAIGAD---HFSVDPVSGN--ITLIKPLDREEK 89 Query: 435 RRYVLTVSATD----SGGRSDTAMVQINIT----DANNYAPVFENAPYTASVFEDAPIGT 486 VS D G +V++ IT D N+ P F+N PY A V EDA +GT Sbjct: 90 DTLKFLVSIRDRVDPEGESERDNVVEVPITFIILDLNDNPPEFQNTPYEADVNEDAAVGT 149 Query: 487 TVL-VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT---GAITTNKLLDRE 542 T+ ++ D D+ + L + S EA + T A+ N L+ Sbjct: 150 TIFDKITVKDRDIVGESLDLKCLPQQQSPEACRKFRLHIIKRDATILEAAVVLNDTLNYN 209 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 Y + A DG P + TT E V DV D PVF+ L T I ED+ + T V Sbjct: 210 QRMVYHFQIEATDG--PHKTQTT-FEARVKDVQDKPPVFQGSLSTV-IDEDSPINTLVLT 265 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES------VATHDLK 656 V A D D G +I Y+L + F++D +G +RT K LDRE+ + + ++ Sbjct: 266 VHARDGDTGEPRKIVYDL--RTNPNDYFLLDAQTGELRTAKPLDREALEDSTGIISLVIR 323 Query: 657 AVAIDGGTPPQ----SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG-EIRA 711 A + G P S+T + I D+NDSPPVF + + EN+ GT + ++ Sbjct: 324 ARELVNGVPSDDPLTSATAKATVTIRDVNDSPPVFNHKEYSVSLLENTLPGTPLALDMSV 383 Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAEL---VTMVDLDYESPRKKYELVIR 768 D D G N+ ++++ D S F +E + + +++ V LDYE+P ++ +V+ Sbjct: 384 SDADVGINS--KFALRLDDVSGVFDVEPKLVTGYSQVNIRVANGTLDYENPNQRKFIVLV 441 Query: 769 AA-----SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV 823 A +P L + + + V D NDN PV + + + P + A D D Sbjct: 442 VAEETDTNPRLSSTATITVSVLDANDNKPVFEQESYSASVSEAALPGQYIATITARDVDS 501 Query: 824 ----TDKLQYRILSGNNANLILLNETTGSMTLS 852 ++Y LSG A L +NE TG ++L+ Sbjct: 502 GSYGDSGIRYS-LSGTGAELFHVNEQTGVISLA 533 Score = 144 bits (348), Expect = 4e-32 Identities = 192/782 (24%), Positives = 323/782 (41%), Gaps = 85/782 (10%) Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 P F++ + + E+++V V+ +++A D + S + Y IG + FS+D +SG Sbjct: 25 PVFTQTLNNIILYENVTV--GTVVFRLEAYDPE---GSPVTYGAIGAD---HFSVDPVSG 76 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQD----GGSPSRSNTTQLLIN--IRDVNDNAPRFYTSL 261 +++L+K LD E+ + + ++ +D G R N ++ I I D+NDN P F + Sbjct: 77 NITLIKPLDREEKDTLKFLVSIRDRVDPEGESERDNVVEVPITFIILDLNDNPPEFQNTP 136 Query: 262 FQESVSENVPIGYSIV-RVQAYDAD-EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319 ++ V+E+ +G +I ++ D D G + +L + + I R + Sbjct: 137 YEADVNEDAAVGTTIFDKITVKDRDIVGESLDLKCLPQQQSPEACRKFRLHIIKRDATIL 196 Query: 320 TSGQLDRET-----QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374 + + +T + Y + ATDG P T F G Sbjct: 197 EAAVVLNDTLNYNQRMVYHFQIEATDG---PHKTQTTFEARVKDVQDKPPVFQ-GSLSTV 252 Query: 375 LAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432 + ED P T V+T+ A D D E ++ Y++ N F + +Q G + A+PLD + Sbjct: 253 IDEDSPINTLVLTVHARDGDTGEPRKIVYDLR-TNPNDYFLLDAQTGE--LRTAKPLDRE 309 Query: 433 Q------------ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 R ++ +D S TA + I D N+ PVF + Y+ S+ E Sbjct: 310 ALEDSTGIISLVIRARELVNGVPSDDPLTSATAKATVTIRDVNDSPPVFNHKEYSVSLLE 369 Query: 481 DAPIGTTV-LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN-PQTGAITTNKL 538 + GT + L +S +D+DVGIN++ L ++S V + + V Q N Sbjct: 370 NTLPGTPLALDMSVSDADVGINSKFALRL-DDVS--GVFDVEPKLVTGYSQVNIRVANGT 426 Query: 539 LDRE--TMSGYLLTVTARDGGV-PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 LD E +++ V A + P LS T + +SV+D NDN+PVF+Q+ Y+A++ E AL Sbjct: 427 LDYENPNQRKFIVLVVAEETDTNPRLSSTATITVSVLDANDNKPVFEQESYSASVSEAAL 486 Query: 596 VGTSVSQVGATDADVGLNG--RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653 G ++ + A D D G G I Y L E F ++ +GVI D Sbjct: 487 PGQYIATITARDVDSGSYGDSGIRYSLSGTGAE--LFHVNEQTGVISLANCHDNGESNRR 544 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713 + + + D H++ +D + + T I + T + Sbjct: 545 ERRDLNED-----------EHVEEDDGEGHLEMLSMEAATREIGTEPTVQYT---LITQA 590 Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP 773 P+E ++V + + T DKA LDYES Y L +A Sbjct: 591 PEEQASSVPLPAPVPHAAPSGVPAAT-ANDDKA---PQTCLDYES-ETTYFLSYKATDDN 645 Query: 774 LWNDVRV---EILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQ 828 V I VTD ND+ PV + ++ + F P V A DAD ++ Sbjct: 646 GRGSASVVSLRISVTDANDSPPVCESPLYRASVDEGAVVFD-SPL-IVKARDADTMSRIS 703 Query: 829 YRILSGNNANLIL-LNETTGSMTLSPQLNTNVPKLAT----MEVSVTDGVNEIKAMMQLS 883 YRI I ++ TG + + P +V L + V DG+ + ++ Sbjct: 704 YRIRGSEQVESIFDIDRETGQIIIRPNATLDVTNLNSDQLIFAVEANDGLFTAHCGVNIT 763 Query: 884 VR 885 VR Sbjct: 764 VR 765 Score = 130 bits (313), Expect = 7e-28 Identities = 136/483 (28%), Positives = 210/483 (43%), Gaps = 54/483 (11%) Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTAT---IHVNIIDDN 144 D F +D SG + LDRE+ LV D+ P + I I+D N Sbjct: 67 DHFSVDPVSGNITLIKPLDREEKDTLKFLVSIRDRVDPEGESERDNVVEVPITFIILDLN 126 Query: 145 DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQ---MQFS 201 DN P+F Y V+ED +V + KI D D+ S + + +F Sbjct: 127 DNPPEFQNTPYEADVNEDAAV-GTTIFDKITVKDRDIVGESLDLKCLPQQQSPEACRKFR 185 Query: 202 IDSLSGDVSLVK-------TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNA 254 + + D ++++ TL+Y Q Y I A DG P ++ TT ++DV D Sbjct: 186 LHIIKRDATILEAAVVLNDTLNYNQRMVYHFQIEATDG--PHKTQTT-FEARVKDVQDKP 242 Query: 255 PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR 314 P F SL + E+ PI ++ V A D D G ++ Y D N + +D + Sbjct: 243 PVFQGSL-STVIDEDSPINTLVLTVHARDGDTGEPRKIVY-----DLRTNPNDYFLLDAQ 296 Query: 315 SGWVYTSGQLDRET----------QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 +G + T+ LDRE + + LV DP SATA Sbjct: 297 TGELRTAKPLDREALEDSTGIISLVIRARELVNGVPSDDPLTSATAKATVTIRDVNDSPP 356 Query: 365 XFMPGQYEVELAEDEPPGTPV-VTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL- 422 F +Y V L E+ PGTP+ + ++ +DAD + + + G F + + G Sbjct: 357 VFNHKEYSVSLLENTLPGTPLALDMSVSDADVGINSKFALRLDDVSGVFDVEPKLVTGYS 416 Query: 423 ---ITVAQ-PLDFK--QERRYVLTVSA--TDSGGR-SDTAMVQINITDANNYAPVFENAP 473 I VA LD++ +R++++ V A TD+ R S TA + +++ DAN+ PVFE Sbjct: 417 QVNIRVANGTLDYENPNQRKFIVLVVAEETDTNPRLSSTATITVSVLDANDNKPVFEQES 476 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGI--NAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 Y+ASV E A G + ++A D D G ++ I YSLS + + F +N QTG Sbjct: 477 YSASVSEAALPGQYIATITARDVDSGSYGDSGIRYSLSGTGA--------ELFHVNEQTG 528 Query: 532 AIT 534 I+ Sbjct: 529 VIS 531 Score = 91.1 bits (216), Expect = 4e-16 Identities = 109/422 (25%), Positives = 184/422 (43%), Gaps = 58/422 (13%) Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523 N PVF ++E+ +GT V + A D + + +TY A H Sbjct: 22 NLPPVFTQTLNNIILYENVTVGTVVFRLEAYDPE---GSPVTYGAIG-------ADH--- 68 Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD--VEIS----VVDVNDN 577 F ++P +G IT K LDRE V+ RD P D VE+ ++D+NDN Sbjct: 69 FSVDPVSGNITLIKPLDREEKDTLKFLVSIRDRVDPEGESERDNVVEVPITFIILDLNDN 128 Query: 578 EPVFKQQLYTANIMEDALVGTSV-SQVGATDADV---GLNGR-IHYELDPKD-REEGSFV 631 P F+ Y A++ EDA VGT++ ++ D D+ L+ + + + P+ R+ + Sbjct: 129 PPEFQNTPYEADVNEDAAVGTTIFDKITVKDRDIVGESLDLKCLPQQQSPEACRKFRLHI 188 Query: 632 IDPASGVIRT----NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687 I + ++ N L+ + + A DG P + +++D+ D PPVF Sbjct: 189 IKRDATILEAAVVLNDTLNYNQRMVYHFQIEATDG---PHKTQTTFEARVKDVQDKPPVF 245 Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747 + L+ I E+SPI T + + A D D G + Y ++ + ++ F L+ + G E Sbjct: 246 QGS-LSTVIDEDSPINTLVLTVHARDGDTGEPRKIVYDLR-TNPNDYFLLDAQTG----E 299 Query: 748 LVTMVDLDYESPRKK---YELVIRA--------ASPPLWN-DVRVEILVTDVNDNAPVMK 795 L T LD E+ LVIRA + PL + + + + DVND+ PV Sbjct: 300 LRTAKPLDREALEDSTGIISLVIRARELVNGVPSDDPLTSATAKATVTIRDVNDSPPVFN 359 Query: 796 DFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQL 855 + + ++ P P A D V+D + N+ + L++ +G + P+L Sbjct: 360 HKEYSVSLLENTLPGTPL----ALDMSVSD----ADVGINSKFALRLDDVSGVFDVEPKL 411 Query: 856 NT 857 T Sbjct: 412 VT 413 Score = 81.0 bits (191), Expect = 4e-13 Identities = 60/209 (28%), Positives = 100/209 (47%), Gaps = 20/209 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTV-LTLKATDQDIGKNAEVEYTIELVTADT 69 + + D ND PVF ++Y S+ E GT + L + +D D+G N++ Sbjct: 346 VTIRDVNDSPPVFNHKEYSVSLLENTLPGTPLALDMSVSDADVGINSKF----------A 395 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L +D V +++ R + +LD E + +V + + + R Sbjct: 396 LRLDDVSGVFDVEPKLVTGYSQVNIR----VANGTLDYENPNQRKFIVLVVAEETDTNPR 451 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA--NSAI 187 LSSTATI V+++D NDN P F +++Y+ SV E + IA I A D D G+ +S I Sbjct: 452 LSSTATITVSVLDANDNKPVFEQESYSASVSE--AALPGQYIATITARDVDSGSYGDSGI 509 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLD 216 RY++ G ++ F ++ +G +SL D Sbjct: 510 RYSLSGTGAEL-FHVNEQTGVISLANCHD 537 Score = 38.3 bits (85), Expect = 3.0 Identities = 53/228 (23%), Positives = 97/228 (42%), Gaps = 31/228 (13%) Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 PPVF + EN +GT + + A+DP+ P V Y G D FS++ G+ Sbjct: 24 PPVFTQTLNNIILYENVTVGTVVFRLEAYDPEGSP---VTYGAIGAD---HFSVDPVSGN 77 Query: 744 DKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR---VEILVT----DVNDNAPVMKD 796 L+ +D + E K+ + IR P R VE+ +T D+NDN P ++ Sbjct: 78 --ITLIKPLDRE-EKDTLKFLVSIRDRVDPEGESERDNVVEVPITFIILDLNDNPPEFQN 134 Query: 797 FQIIFNNYKDCFPVGP--FGRVPAYDADVT-DKLQYRILSGNNA---------NLILLNE 844 + +D VG F ++ D D+ + L + L + ++I + Sbjct: 135 TPYEADVNEDA-AVGTTIFDKITVKDRDIVGESLDLKCLPQQQSPEACRKFRLHIIKRDA 193 Query: 845 T--TGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEE 890 T ++ L+ LN N + ++ TDG ++ + + V+ + ++ Sbjct: 194 TILEAAVVLNDTLNYNQRMVYHFQIEATDGPHKTQTTFEARVKDVQDK 241 >UniRef50_Q9Y5F6 Cluster: Protocadherin gamma C5 precursor; n=49; Tetrapoda|Rep: Protocadherin gamma C5 precursor - Homo sapiens (Human) Length = 944 Score = 252 bits (618), Expect = 8e-65 Identities = 178/617 (28%), Positives = 277/617 (44%), Gaps = 24/617 (3%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F + SGAL +DRE + + Q V++ + V I+D NDN P Sbjct: 75 FSLSLMSGALAVNQKIDRESLCGASTSCLLPVQV--VTEHPLELIRVEVEILDLNDNSPS 132 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG-- 207 F+ + + E S A D DVG N+ Y + N+ ++ +L Sbjct: 133 FATPEREMRISE--SAASGARFPLDSAQDPDVGTNTVSFYTL-SPNSHFSLNVKTLKDGK 189 Query: 208 ---DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 ++ L + LD E ++LV+ A DGG+P+RS TT + + + D+NDNAP F +S+ + Sbjct: 190 PFPELVLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRV 249 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 + EN PIG ++R+ A D DEG N +L Y+ D +L +DP SG ++ G + Sbjct: 250 GIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNL-FGLDPSSGAIHVLGPI 308 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 D E Y++ A D G P + + E P GT Sbjct: 309 DFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTV 368 Query: 385 VVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444 V D D + S+N L+T +QPLD + Y++ + A+ Sbjct: 369 VGLFNVRDRDSGRNGEVSLDISPDLPFQIKPSENHYSLLT-SQPLDREATSHYIIELLAS 427 Query: 445 DSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502 D+G S +++NI+D N+ AP F YTA + E+ P G+ + V+A+D D G NA Sbjct: 428 DAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNA 487 Query: 503 QITYSLSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL 561 ++TYS+ + N+ FV +NP+ G I + D E + + V RD G P L Sbjct: 488 RLTYSI---VGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPL 544 Query: 562 SDTTDVEISVVDVNDNEPVFK------QQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615 T + + V+D NDN P + + A G+ V++V A DAD G N Sbjct: 545 HANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAW 604 Query: 616 IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675 + Y L P+ G F++ +G +RT +AL + T + + D G P SST V + Sbjct: 605 LSYSLLPQSTAPGLFLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLL 664 Query: 676 KIEDINDSPPVFESDCL 692 +ED + SD L Sbjct: 665 VLEDEDPEEMPKSSDFL 681 Score = 214 bits (523), Expect = 3e-53 Identities = 166/578 (28%), Positives = 260/578 (44%), Gaps = 39/578 (6%) Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT-DKDYTG 303 + I D+NDN+P F T + +SE+ G A D D G N YT++ + ++ Sbjct: 121 VEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSL 180 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 NV P V QLDRE QA++QL++TA DGG P RS T Sbjct: 181 NVKTLKDGKPFPELVLEQ-QLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNA 239 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI---TGGNTRGRFSITSQN 418 F V + E+ P GT ++ L ATD DE + +L Y T R F + + Sbjct: 240 PTFQSSVLRVGIPENAPIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSS 299 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTA 476 G I V P+DF++ R Y + A D G ++Q+++ D N+ AP A Sbjct: 300 GA--IHVLGPIDFEESRFYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLAN 357 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG--AIT 534 V E P+GT V + + D D G N +++ +S ++ F I P ++ Sbjct: 358 PVLESTPVGTVVGLFNVRDRDSGRNGEVSLDISPDLP----------FQIKPSENHYSLL 407 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 T++ LDRE S Y++ + A D G PSL + +++ DVNDN P F QQLYTA I+E+ Sbjct: 408 TSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNISDVNDNAPRFNQQLYTAYILENR 467 Query: 595 LVGTSVSQVGATDADVGLNGRIHYEL---DPKDREEGSFV-IDPASGVIRTNKALDRESV 650 G+ + V A+D D G N R+ Y + + SFV ++P G I + D E + Sbjct: 468 PPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELL 527 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE------SDCLTFYISENSPIGT 704 + D G+PP + +H+ + D ND+ P + ++P G+ Sbjct: 528 QMLQIVVGVRDSGSPPLHANTSLHVFVLDENDNAPAVLHPRPDWEHSAPQRLPRSAPPGS 587 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDS-NSFSLETRQGSDKAELVTMVDLDYESPRKKY 763 + ++ A D D G NA + YS+ + F + T G + + D +S ++ Sbjct: 588 LVTKVTAVDADAGHNAWLSYSLLPQSTAPGLFLVSTHTGEVRTARALLED---DSDTQQV 644 Query: 764 ELVIRAASPPLWNDVRVEILVTDVND--NAPVMKDFQI 799 +++R P + +LV + D P DF I Sbjct: 645 VVLVRDNGDPSLSSTATVLLVLEDEDPEEMPKSSDFLI 682 Score = 198 bits (483), Expect = 2e-48 Identities = 167/593 (28%), Positives = 266/593 (44%), Gaps = 57/593 (9%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 I ++ +LD ND+SP F + E + E A+SG A D D+G N YT+ + Sbjct: 117 IRVEVEILDLNDNSPSFATPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNS 176 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRS-GALLTRASLDREKVARYTVLVKATDQASP 125 +LN + DG+ L+ LDRE AR+ +++ A D +P Sbjct: 177 HFSLNVKTLK----------------DGKPFPELVLEQQLDREAQARHQLVLTAVDGGTP 220 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 S T I V ++D NDN P F V + E+ + ++ ++ ATD D G N Sbjct: 221 AR---SGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPI--GTLLLRLNATDPDEGTNG 275 Query: 186 AIRYAIIGGNT----QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 + Y+ G +T + F +D SG + ++ +D+E+ R Y + RA+D G P+ Sbjct: 276 QLDYS-FGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESRFYEIHARARDQGQPAMEGHC 334 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 + +++ DVNDNAP + V E+ P+G + D D G N E++ ++ Sbjct: 335 VIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNVRDRDSGRNGEVSLDISP--- 391 Query: 302 TGNVDLPITIDPRSGW--VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 DLP I P + TS LDRE + Y + + A+D G P T Sbjct: 392 ----DLPFQIKPSENHYSLLTSQPLDREATSHYIIELLASDAGSPSLHKHLTIRLNISDV 447 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DN-RLHYEITGGNTRG--RFSIT 415 F Y + E+ PPG+ + T+ A+D D DN RL Y I G +G S Sbjct: 448 NDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSIVGNQVQGAPASSFV 507 Query: 416 SQNGR-GLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAP-VFE 470 N G I + D++ + + V DSG ++T++ + + D N+ AP V Sbjct: 508 YVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSL-HVFVLDENDNAPAVLH 566 Query: 471 NAP---YTA--SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525 P ++A + AP G+ V V+A D+D G NA ++YSL + + + F+ Sbjct: 567 PRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQSTAPGL------FL 620 Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578 ++ TG + T + L + + V RD G PSLS T V + + D + E Sbjct: 621 VSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVLLVLEDEDPEE 673 Score = 132 bits (318), Expect = 2e-28 Identities = 103/329 (31%), Positives = 156/329 (47%), Gaps = 27/329 (8%) Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 SV E++ GT V V+ D+G+ S ++ +E + + F ++ +GA+ N Sbjct: 34 SVVEESEPGTLVGNVA---QDLGLKMTDLLSRRLQLGSE---ENGRYFSLSLMSGALAVN 87 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLS-DTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 + +DRE++ G + V + VE+ ++D+NDN P F I E A Sbjct: 88 QKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFATPEREMRISESAA 147 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI----DPASGVIRTNKALDRESVA 651 G A D DVG N Y L P + P ++ + LDRE+ A Sbjct: 148 SGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPELV-LEQQLDREAQA 206 Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711 H L A+DGGTP +S T ++ + + DIND+ P F+S L I EN+PIGT + + A Sbjct: 207 RHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPENAPIGTLLLRLNA 266 Query: 712 HDPDEGPNAVVHYSIKGGDDS-----NSFSLETRQGSDKAELVTMVDLDYESPRKKYELV 766 DPDEG N + YS GD + N F L+ G+ + + +D+E R YE+ Sbjct: 267 TDPDEGTNGQLDYSF--GDHTSEAVRNLFGLDPSSGA----IHVLGPIDFEESR-FYEIH 319 Query: 767 IRA---ASPPLWNDVRVEILVTDVNDNAP 792 RA P + +++ V DVNDNAP Sbjct: 320 ARARDQGQPAMEGHCVIQVDVGDVNDNAP 348 >UniRef50_Q5ICW6 Cluster: Protocadherin 15a; n=8; Clupeocephala|Rep: Protocadherin 15a - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 1796 Score = 248 bits (608), Expect = 1e-63 Identities = 238/832 (28%), Positives = 386/832 (46%), Gaps = 59/832 (7%) Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKAT-DQASPVSDRLSSTATIHVNIIDDNDN 146 + F ++ + L S+DRE R+++++KA D P L + + + + I+D+N+ Sbjct: 341 EFFTLNRSTAELRLLKSVDRELYQRFSLVIKAEQDNGHP----LPAYSKLEIEILDENNQ 396 Query: 147 YPQFSEKTYTVSVDEDISV-TDNPVIAKIKAT------DADVGANSAIRYAIIGGNTQMQ 199 P F + +Y V E SV T A + A D D+ + I Sbjct: 397 APYFQQSSYRGFVSESSSVGTTISASANLTAPLAIIALDNDIEETKDPQLKITLNEYTSI 456 Query: 200 FSIDS--LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF 257 F+I + ++ ++L+K +D E +Y L + A DG SR T +L+ D NDN P F Sbjct: 457 FTITTSGITRFLTLLKPVDREIQTNYTLTLVATDGVQQSRPVTVDILVI--DANDNTPTF 514 Query: 258 YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317 + + N+ G +++++ A DAD G+N +TY + D+ + I+ R+G Sbjct: 515 AQVSYSVEIFTNMLPGETVLQLMAQDADAGLNGLITYAILAGDHGDFI-----INNRTGR 569 Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXXXXFMPGQ-YEVE 374 + + + Y L V A D RS+ T P Q Y +E Sbjct: 570 ITLAPGVMLTVGRSYALTVRAADNAPDTERRSSITTVYIEVLPPNNQSPPRFPLQTYNLE 629 Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434 ++E G ++ L ATD + D + Y I G+ + F+++ G L+ +A+PLD + Sbjct: 630 ISEAMRIGAILLNLQATDRELDP-ITYRIETGDPQEVFNLSRTIG--LLLLAKPLDRETI 686 Query: 435 RRYVLTVSATDSG-GRSDTAMVQINITDANNYAPVFE-NAPYTASVFEDAPIGTTVLVVS 492 +Y L V+A+D G TA V I ITD N+ P F+ P +V E+ V V Sbjct: 687 DQYRLIVTASDGHPGGISTATVSIVITDVNDNDPTFDLTLPRNLTVREEEA-NVFVGQVR 745 Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552 ATD D G+N Q+ Y L S S F IN TG+I T LDRET S Y L V Sbjct: 746 ATDPDGGLNGQVRYRLLSFAS---------LFSIN-STGSIFTAVPLDRETRSRYDLIVE 795 Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612 A DG V T + + V+D+NDN PVF Q +YT N+ E+ G+ + ++ A DAD+ Sbjct: 796 ASDGAVDPRRTTITLLVEVLDINDNSPVFSQPVYTVNVPENTPAGSIILRLTAVDADLVS 855 Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA----THDLKAVAIDGGTPPQS 668 N + Y + + + F ++ +GVI +ALD ES+A T+ + A+D G Sbjct: 856 N--VTYRIKTEAALQ-LFAVNRLTGVISVLQALDFESLAAGNSTYTFEVEALDHGGVLPP 912 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA--HDPDEGPNAVVHYSI 726 T V ++I D+ND PVF ++ N+ GT I + A DP P + V Y + Sbjct: 913 GTATVSVRITDMNDFSPVFRQALYKGLVAPNAEKGTVITTVLAEDQDPPGTPASKVRYRV 972 Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEIL 783 S S+ + +D ++T V+L+ E P ++LV+ A P N VEI Sbjct: 973 DQELSPYSGSIFDVE-TDTGLVITKVNLN-EQPTTVFKLVVMAYDDGEPVKTNRTTVEIT 1030 Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLILL 842 V + P+ + + F+ + P+G P G + A + T + Y I+SGN + + Sbjct: 1031 VLQPS-RIPIFTEEEYRFSPVSENAPIGTPVGLILAAATNTT--VVYSIVSGNEGGVFTV 1087 Query: 843 NETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLN 894 N++TG + + L+ + V D + I A ++ + T ++ +N Sbjct: 1088 NKSTGIIYTNKSLDYENVTSYVLRVQ-ADSLTVILANLRAPSKTNTAKVFIN 1138 Score = 248 bits (606), Expect = 2e-63 Identities = 257/848 (30%), Positives = 378/848 (44%), Gaps = 109/848 (12%) Query: 7 IHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-----LKATDQDIGKNAEVEY 60 +H+ +I V D ND++P F+ +Y SV E GTT+ T ATD D G N ++EY Sbjct: 135 LHEVRIVVRDRNDNTPRFQQPRYYVSVNELTPVGTTIFTGFSGNNGATDIDDGPNGQIEY 194 Query: 61 TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGR-SGALLTRASLDREKVARYTVLVKA 119 I+ NP D RI G SG ++ L+ E+ RY ++V+A Sbjct: 195 AIQY------NPNDPMSNRTV---------RIAGTLSGNIVLAERLNYEERTRYLIIVQA 239 Query: 120 TDQASPVSDRLSSTATIHVNIIDDNDNYPQF------------SEKTYTVSVDEDISVTD 167 D+A R ++T T+ ++++D +D P F + TY V++ E Sbjct: 240 NDRAPYPGTRRTATTTLTLDVLDGDDLGPMFLPCVLVNNTQDCNPVTYRVAIPELTDPNK 299 Query: 168 -NP--VIAKIKATDAD-----VGANSAIRYAIIGGNTQMQ---FSIDSLSGDVSLVKTLD 216 NP V I+A D D I Y I+ G F+++ + ++ L+K++D Sbjct: 300 LNPLNVTPPIRAIDQDRNIQPPSDRPGILYFILVGTPSTYPEFFTLNRSTAELRLLKSVD 359 Query: 217 YEQVRSYRLVIRA-QDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275 E + + LVI+A QD G P + ++L I I D N+ AP F S ++ VSE+ +G + Sbjct: 360 RELYQRFSLVIKAEQDNGHPLPA-YSKLEIEILDENNQAPYFQQSSYRGFVSESSSVGTT 418 Query: 276 IVRVQAYDADEGVNAELTYTMTDKDY--TGNVDLPITIDPRSG--WVYTSG--------- 322 I A + A L D D T + L IT++ + + TSG Sbjct: 419 I------SASANLTAPLAIIALDNDIEETKDPQLKITLNEYTSIFTITTSGITRFLTLLK 472 Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382 +DRE Q Y L + ATDG +S T F Y VE+ + PG Sbjct: 473 PVDREIQTNYTLTLVATDG--VQQSRPVTVDILVIDANDNTPTFAQVSYSVEIFTNMLPG 530 Query: 383 TPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440 V+ L A DAD + + Y I G+ G F I ++ GR IT+A + R Y LT Sbjct: 531 ETVLQLMAQDADAGLNGLITYAILAGD-HGDFIINNRTGR--ITLAPGVMLTVGRSYALT 587 Query: 441 VSATDSG----GRSDTAMVQINITDANNYAPV-FENAPYTASVFEDAPIGTTVLVVSATD 495 V A D+ RS V I + NN +P F Y + E IG +L + ATD Sbjct: 588 VRAADNAPDTERRSSITTVYIEVLPPNNQSPPRFPLQTYNLEISEAMRIGAILLNLQATD 647 Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555 ++ ITY + + E F ++ G + K LDRET+ Y L VTA D Sbjct: 648 RELD---PITYRIETGDPQEV-------FNLSRTIGLLLLAKPLDRETIDQYRLIVTASD 697 Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615 G +S T V I + DVNDN+P F L + + V QV ATD D GLNG+ Sbjct: 698 GHPGGIS-TATVSIVITDVNDNDPTFDLTLPRNLTVREEEANVFVGQVRATDPDGGLNGQ 756 Query: 616 IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675 + Y L S ++G I T LDRE+ + +DL A DG P+ +T+ + + Sbjct: 757 VRYRL----LSFASLFSINSTGSIFTAVPLDRETRSRYDLIVEASDGAVDPRRTTITLLV 812 Query: 676 KIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735 ++ DIND+ PVF T + EN+P G+ I + A D D N V Y IK F Sbjct: 813 EVLDINDNSPVFSQPVYTVNVPENTPAGSIILRLTAVDADLVSN--VTYRIKTEAALQLF 870 Query: 736 SLETRQGSDKAELVTMVDLDYES---PRKKYELVIRAAS-----PPLWNDVRVEILVTDV 787 ++ G + + LD+ES Y + A PP V + +TD+ Sbjct: 871 AVNRLTG----VISVLQALDFESLAAGNSTYTFEVEALDHGGVLPP--GTATVSVRITDM 924 Query: 788 NDNAPVMK 795 ND +PV + Sbjct: 925 NDFSPVFR 932 Score = 246 bits (602), Expect = 7e-63 Identities = 240/852 (28%), Positives = 378/852 (44%), Gaps = 78/852 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I +LD N+ +P F+ Y V E +S GTT I +A + + ++ D Sbjct: 387 EIEILDENNQAPYFQQSSYRGFVSESSSVGTT----------ISASANLTAPLAIIALDN 436 Query: 70 LNPEDAXXXXXXXXXXVQDVFRI--DGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 E +F I G + L +DRE YT+ + ATD Sbjct: 437 DIEETKDPQLKITLNEYTSIFTITTSGITRFLTLLKPVDREIQTNYTLTLVATDGVQQ-- 494 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 S T+ + +ID NDN P F++ +Y+V + ++ + ++ A DAD G N I Sbjct: 495 ---SRPVTVDILVIDANDNTPTFAQVSYSVEIFTNM--LPGETVLQLMAQDADAGLNGLI 549 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS--RSNTTQLLI 245 YAI+ G+ F I++ +G ++L + RSY L +RA D + RS+ T + I Sbjct: 550 TYAILAGD-HGDFIINNRTGRITLAPGVMLTVGRSYALTVRAADNAPDTERRSSITTVYI 608 Query: 246 NIRDVNDNAP-RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + N+ +P RF + +SE + IG ++ +QA D + +TY + D Sbjct: 609 EVLPPNNQSPPRFPLQTYNLEISEAMRIGAILLNLQATDRELD---PITYRIETGDPQEV 665 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 +L TI G + + LDRET +Y+L+VTA+DG P +TAT Sbjct: 666 FNLSRTI----GLLLLAKPLDRETIDQYRLIVTASDG-HPGGISTATVSIVITDVNDNDP 720 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGL 422 F +E V + ATD D + ++ Y + + FSI N G Sbjct: 721 TFDLTLPRNLTVREEEANVFVGQVRATDPDGGLNGQVRYRLL--SFASLFSI---NSTGS 775 Query: 423 ITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 I A PLD + RY L V A+D R T + + + D N+ +PVF YT +V E Sbjct: 776 IFTAVPLDRETRSRYDLIVEASDGAVDPRRTTITLLVEVLDINDNSPVFSQPVYTVNVPE 835 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 + P G+ +L ++A D+D+ N +TY + +E + Q F +N TG I+ + LD Sbjct: 836 NTPAGSIILRLTAVDADLVSN--VTYRIKTEAAL-------QLFAVNRLTGVISVLQALD 886 Query: 541 RETM----SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 E++ S Y V A D G T V + + D+ND PVF+Q LY + +A Sbjct: 887 FESLAAGNSTYTFEVEALDHGGVLPPGTATVSVRITDMNDFSPVFRQALYKGLVAPNAEK 946 Query: 597 GTSVSQVGATDADVGLN--GRIHYELDPK-DREEGS-FVIDPASGVIRTNKALDRESVAT 652 GT ++ V A D D ++ Y +D + GS F ++ +G++ T L+ + Sbjct: 947 GTVITTVLAEDQDPPGTPASKVRYRVDQELSPYSGSIFDVETDTGLVITKVNLNEQPTTV 1006 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 L +A D G P +++ V I + + P E + +SEN+PIGT +G I A Sbjct: 1007 FKLVVMAYDDGEPVKTNRTTVEITVLQPSRIPIFTEEEYRFSPVSENAPIGTPVGLILA- 1065 Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS- 771 N V YSI G++ F++ G + T LDYE+ Y L ++A S Sbjct: 1066 ---AATNTTVVYSIVSGNEGGVFTVNKSTGI----IYTNKSLDYENVTS-YVLRVQADSL 1117 Query: 772 ---------PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD 822 P N +V I V D ND+ PV I +D ++ A D D Sbjct: 1118 TVILANLRAPSKTNTAKVFINVQDENDHPPVFSRQVYIGGVTEDTKTFTTVLKIVATDVD 1177 Query: 823 VTD--KLQYRIL 832 + K+ YR++ Sbjct: 1178 TGNYSKMAYRLI 1189 Score = 217 bits (530), Expect = 4e-54 Identities = 220/758 (29%), Positives = 335/758 (44%), Gaps = 77/758 (10%) Query: 11 INVLDCNDHSPV-FEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 I VL N+ SP F +Q Y + E G +L L+ATD+++ + Y IE T D Sbjct: 608 IEVLPPNNQSPPRFPLQTYNLEISEAMRIGAILLNLQATDRELDP---ITYRIE--TGDP 662 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 Q+VF + G LL LDRE + +Y ++V A+D P Sbjct: 663 -----------------QEVFNLSRTIGLLLLAKPLDRETIDQYRLIVTASD-GHPGG-- 702 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTD---NPVIAKIKATDADVGANSA 186 STAT+ + I D NDN P T+ +++ +++V + N + +++ATD D G N Sbjct: 703 -ISTATVSIVITDVNDNDP-----TFDLTLPRNLTVREEEANVFVGQVRATDPDGGLNGQ 756 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 +RY ++ + FSI+S +G + LD E Y L++ A DG R T LL+ Sbjct: 757 VRYRLL--SFASLFSINS-TGSIFTAVPLDRETRSRYDLIVEASDGAVDPRRTTITLLVE 813 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + D+NDN+P F ++ +V EN P G I+R+ A DAD + + +TY + + + Sbjct: 814 VLDINDNSPVFSQPVYTVNVPENTPAGSIILRLTAVDAD--LVSNVTYRIKTE---AALQ 868 Query: 307 LPITIDPRSGWVYTSGQLDRETQAK----YQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 L ++ +G + LD E+ A Y V A D G TAT Sbjct: 869 L-FAVNRLTGVISVLQALDFESLAAGNSTYTFEVEALDHGGVLPPGTATVSVRITDMNDF 927 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADED----NRLHYEITGGNTRGRFSITS-Q 417 F Y+ +A + GT + T+ A D D +++ Y + + SI + Sbjct: 928 SPVFRQALYKGLVAPNAEKGTVITTVLAEDQDPPGTPASKVRYRVDQELSPYSGSIFDVE 987 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDAN-NYAPVFENAPYTA 476 GL+ L+ + + L V A D G T + IT + P+F Y Sbjct: 988 TDTGLVITKVNLNEQPTTVFKLVVMAYDDGEPVKTNRTTVEITVLQPSRIPIFTEEEYRF 1047 Query: 477 S-VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 S V E+APIGT V ++ A + N + YS+ S NE F +N TG I T Sbjct: 1048 SPVSENAPIGTPVGLILAAAT----NTTVVYSIVS--GNEGGV-----FTVNKSTGIIYT 1096 Query: 536 NKLLDRETMSGYLLTVTARDGGV-------PSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588 NK LD E ++ Y+L V A V PS ++T V I+V D ND+ PVF +Q+Y Sbjct: 1097 NKSLDYENVTSYVLRVQADSLTVILANLRAPSKTNTAKVFINVQDENDHPPVFSRQVYIG 1156 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALD 646 + ED T+V ++ ATD D G ++ Y L P + SFVI+P +GVI++ Sbjct: 1157 GVTEDTKTFTTVLKIVATDVDTGNYSKMAYRLIIPPTTEGQDSFVIEPYTGVIKSAIMFR 1216 Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706 + + VA D +S V + + + D V S+ + EN +I Sbjct: 1217 NMRRSYFKFQVVATDDYGKGLTSKADVVVSVVNALDM-QVVVSNVPPTVVEENKEQLISI 1275 Query: 707 GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD 744 E D G +V SI + LE SD Sbjct: 1276 LERYVQDQIPGAKVIVE-SIGPRRHGEGYELEDYSKSD 1312 >UniRef50_Q9VAF5 Cluster: CG31009-PA; n=9; Diptera|Rep: CG31009-PA - Drosophila melanogaster (Fruit fly) Length = 1706 Score = 246 bits (601), Expect = 9e-63 Identities = 252/885 (28%), Positives = 391/885 (44%), Gaps = 81/885 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVL-TLKATDQDIGKNAEVEYTIELVTADT 69 + V D ND++P F YE +V E GTT+ ++A D+D G N VEY I + ++ Sbjct: 130 VRVSDINDNAPRFMNTPYEVTVPESTPVGTTIFRNIQALDKDAGVNGLVEYFIAEGSPNS 189 Query: 70 LNPEDAXXXXXXXXXXVQDVFRID-GRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 N E F I G + +LD EK+ Y + + A+D+A +D Sbjct: 190 TNVEKYSADGYGT-------FAISFPHQGQVTVAKTLDFEKIQTYYLTIVASDRARNTAD 242 Query: 129 RLSSTATIHVNIIDDNDNYPQF------SEKTYTVSVDEDISVTDNPVIA-------KIK 175 RLSST T+ VNI D ND P F S ++ + SV ++ +I+ Sbjct: 243 RLSSTTTLTVNIADSNDLDPSFIYSGCVSLDGACINPEYSASVPAGSLLGVLTVLPERIQ 302 Query: 176 ATDADVGANSAIRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD- 231 A D D NS IRY+ + GN F ID +G + K +D + Y ++++A++ Sbjct: 303 AVDLDT-INSPIRYSFASGMPGNYADYFQIDESTGVLKQTKAVDTSTAKKYDIIVKAEEV 361 Query: 232 GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNA 290 P R T +L I ++ V+ N P +S + V EN PIG ++ +A Sbjct: 362 SPGPQRFTTAKLEIFVKPVDANPPVISSSQAEGYVDENSPIGTRVLDAHGNPISFMTTDA 421 Query: 291 ELTYTMTDKDYTGNVDLP-ITIDPRSGWVYTSGQLDRETQA--KYQLLVTATDGGDPPRS 347 +L+ + DY + P + V LDR+ A +++ V A + PR+ Sbjct: 422 DLSDSDPKPDYIYELTTPSFNVTGDGILVVNEENLDRDPPAPGRFKFQVVARE----PRT 477 Query: 348 ATATXXXXXXXXXXXXXXFMPGQYEVE----LAEDEPPGTPVVTLTATDADEDNR--LHY 401 A+ P V A D+ V +TATD DE + Y Sbjct: 478 NAASAPLSLTVHLRDVNDNAPKLAMVAPISITAGDQSESRLVTQVTATDNDEGPNAVVTY 537 Query: 402 EITGGNTRG--RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINI 459 I + G +F+I + G + T + L +Q Y +TV ATD GG S A+V++++ Sbjct: 538 SIYHVSNNGIQKFTINATTGE-IRTQGRLLAGEQ---YSITVQATDIGGLSSQAIVEVSV 593 Query: 460 TDA-NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518 T N P F+ Y V E A I +TV VV A D + N + YS+ S N+ Sbjct: 594 TPGPNTKPPRFQKPIYEVQVSEGAEINSTVTVVHAEDPE---NDAVVYSIIS--GNDL-- 646 Query: 519 HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578 +QF + ++G I + LDRE+++ Y L + A D G LS + V I V D+ND Sbjct: 647 ---RQFAVGQESGVIIVIRKLDRESLTRYQLILKAEDTG--GLSSSATVNIKVTDINDKN 701 Query: 579 PVFK-QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637 P F+ L +E+ SV V ATDAD G+N I Y + P D F I+ SG Sbjct: 702 PEFEASTLPYVFQVEEGKAQASVGVVHATDADEGINAEITYSI-PTDI---PFTINATSG 757 Query: 638 VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697 I T K LD E + + A DG + T V + + D+ D P F + +I Sbjct: 758 EILTAKELDYEQLNEYKFVVTAKDGAPDARLGTASVTVMVLDLPDEVPKFSDARIDVHIP 817 Query: 698 ENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757 EN + ++A DPD P + Y ++ G ++ F + + G E+ T+ LDYE Sbjct: 818 ENEE-NFLVATVQAFDPDSMPE--ITYVLRKG-NAELFKVSEKSG----EVRTIKGLDYE 869 Query: 758 SPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN--NYKDCFPVGP-FG 814 S +K+++L I +LV DV D + F + + D +G Sbjct: 870 S-QKQHQLTIGTIENDGNGPGDTILLVVDVEDRNDLPPRFITVPDPVTVNDDQGIGTIIA 928 Query: 815 RVPAYDADVT---DKLQYRILS-GNNANLILLNETTGSMTLSPQL 855 +PA D D T + ++Y I+ G ++ TG++ + +L Sbjct: 929 TLPAIDGDGTSPGNVVRYEIVGRGKAPKYFQVDPDTGAVRIRDEL 973 Score = 224 bits (547), Expect = 3e-56 Identities = 223/774 (28%), Positives = 342/774 (44%), Gaps = 54/774 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVR-EGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +N+ D ND P F Y V +GA +G + I+ V DT Sbjct: 252 VNIADSNDLDPSFI---YSGCVSLDGACINPEYSASVPAGSLLGVLTVLPERIQAVDLDT 308 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 +N D F+ID +G L ++D +Y ++VKA ++ SP R Sbjct: 309 INSPIRYSFASGMPGNYADYFQIDESTGVLKQTKAVDTSTAKKYDIIVKA-EEVSPGPQR 367 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED-------ISVTDNPVIAKIKATDADVG 182 + TA + + + + N P S VDE+ + NP+ TDAD+ Sbjct: 368 FT-TAKLEIFVKPVDANPPVISSSQAEGYVDENSPIGTRVLDAHGNPI--SFMTTDADL- 423 Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSLV---KTLDYEQVRS--YRLVIRAQDGGSPSR 237 ++S + I T F++ +GD LV + LD + ++ + A++ + + Sbjct: 424 SDSDPKPDYIYELTTPSFNV---TGDGILVVNEENLDRDPPAPGRFKFQVVAREPRTNAA 480 Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297 S L +++RDVNDNAP+ + + + +V A D DEG NA +TY++ Sbjct: 481 SAPLSLTVHLRDVNDNAPKLAMVAPISITAGDQSESRLVTQVTATDNDEGPNAVVTYSIY 540 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357 + N TI+ +G + T G+L Q Y + V ATD G A Sbjct: 541 H--VSNNGIQKFTINATTGEIRTQGRLLAGEQ--YSITVQATDIGGLSSQAIVEVSVTPG 596 Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ 417 F YEV+++E + V + A D + D + Y I GN +F++ + Sbjct: 597 PNTKPPR-FQKPIYEVQVSEGAEINSTVTVVHAEDPEND-AVVYSIISGNDLRQFAVGQE 654 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENA--PYT 475 +G +I V + LD + RY L + A D+GG S +A V I +TD N+ P FE + PY Sbjct: 655 SG--VIIVIRKLDRESLTRYQLILKAEDTGGLSSSATVNIKVTDINDKNPEFEASTLPYV 712 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 V E+ +V VV ATD+D GINA+ITYS+ ++I F IN +G I T Sbjct: 713 FQV-EEGKAQASVGVVHATDADEGINAEITYSIPTDIP----------FTINATSGEILT 761 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 K LD E ++ Y VTA+DG + T V + V+D+ D P F +I E+ Sbjct: 762 AKELDYEQLNEYKFVVTAKDGAPDARLGTASVTVMVLDLPDEVPKFSDARIDVHIPENE- 820 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655 V+ V A D D I Y L + E F + SG +RT K LD ES H L Sbjct: 821 ENFLVATVQAFDPD--SMPEITYVLRKGNAE--LFKVSEKSGEVRTIKGLDYESQKQHQL 876 Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 I+ T+++ + +ED ND PP F + ++++ IGT I + A D D Sbjct: 877 TIGTIENDGNGPGDTILLVVDVEDRNDLPPRFITVPDPVTVNDDQGIGTIIATLPAIDGD 936 Query: 716 -EGPNAVVHYSIKG-GDDSNSFSLETRQGSDKA--ELVTMVDLDYESPRKKYEL 765 P VV Y I G G F ++ G+ + EL D +Y+ + Y+L Sbjct: 937 GTSPGNVVRYEIVGRGKAPKYFQVDPDTGAVRIRDELRKEEDTEYQVDIRAYDL 990 Score = 218 bits (532), Expect = 2e-54 Identities = 206/768 (26%), Positives = 343/768 (44%), Gaps = 88/768 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-LKATDQDIGKNAEVEYTIELVTADT 69 +++ D ND++P M S+ G S + ++T + ATD D G NA V Y+I V+ + Sbjct: 488 VHLRDVNDNAPKLAMVA-PISITAGDQSESRLVTQVTATDNDEGPNAVVTYSIYHVSNNG 546 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + F I+ +G + T+ L + +Y++ V+ATD Sbjct: 547 IQK-----------------FTINATTGEIRTQGRLLAGE--QYSITVQATDIGG----- 582 Query: 130 LSSTATIHVNIIDD-NDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 LSS A + V++ N P+F + Y V V E + N + + A D + N A+ Sbjct: 583 LSSQAIVEVSVTPGPNTKPPRFQKPIYEVQVSEGAEI--NSTVTVVHAEDPE---NDAVV 637 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y+II GN QF++ SG + +++ LD E + Y+L+++A+D G S S T I + Sbjct: 638 YSIISGNDLRQFAVGQESGVIIVIRKLDRESLTRYQLILKAEDTGGLSSSATVN--IKVT 695 Query: 249 DVNDNAPRFYTSLFQESVS-ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 D+ND P F S E S+ V A DADEG+NAE+TY++ D+ Sbjct: 696 DINDKNPEFEASTLPYVFQVEEGKAQASVGVVHATDADEGINAEITYSIP-------TDI 748 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 P TI+ SG + T+ +LD E +Y+ +VTA DG R TA+ F Sbjct: 749 PFTINATSGEILTAKELDYEQLNEYKFVVTAKDGAPDARLGTASVTVMVLDLPDEVPKFS 808 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 + +V + E+E V T+ A D D + Y + GN F ++ ++G + + Sbjct: 809 DARIDVHIPENEE-NFLVATVQAFDPDSMPEITYVLRKGNAE-LFKVSEKSGE--VRTIK 864 Query: 428 PLDFKQERRYVLTVSA--TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 LD++ ++++ LT+ D G DT ++ +++ D N+ P F P +V +D IG Sbjct: 865 GLDYESQKQHQLTIGTIENDGNGPGDTILLVVDVEDRNDLPPRFITVPDPVTVNDDQGIG 924 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 T + + A D D + + EI A + F ++P TGA+ L +E + Sbjct: 925 TIIATLPAIDGDGTSPGNV---VRYEIVGRGKA--PKYFQVDPDTGAVRIRDELRKEEDT 979 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISV---VDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 Y + + A D G P LS + + V + +NE +L + M +G + S Sbjct: 980 EYQVDIRAYDLGEPQLSSVAPLRVDVHHLLSSGNNEIKLDNKLESGTGMSSESIGLAFSD 1039 Query: 603 VGATDA-----DVGLNGRIHYELDPKDREEG------SFVIDPASGVIRTNKA------- 644 T + + ++ ++ K +G FV G+ + A Sbjct: 1040 DSYTTSVPESMEANSTLKLIQIVNSKTSGDGPPAFRCEFVSGNGGGIFNLSSADHGCNLL 1099 Query: 645 ----LDRESVATHDLKAVAIDGG--TPPQSSTVIVHIKIEDINDSPPVFESDCL-----T 693 LD E+ +++ L+ P T V I ++D ND+ P FE + L T Sbjct: 1100 LIQPLDFENKSSYSLQLRLTSHRYFVNPLKDTTSVEIIVQDENDNAPEFEFNRLRGQQDT 1159 Query: 694 FY--ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLET 739 FY ++E + TTI ++RA D D G V Y++ DD N ++ T Sbjct: 1160 FYTVVTEEMDVDTTILQVRATDRDSGKFGTVRYTLY-DDDENRVNMPT 1206 Score = 213 bits (521), Expect = 4e-53 Identities = 233/816 (28%), Positives = 352/816 (43%), Gaps = 91/816 (11%) Query: 87 QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146 Q +F+++G+ LL D E ++ V T + S T I V + D NDN Sbjct: 83 QPIFQLNGKKLQLLQPLDRDEENLSHIVFQVSCTTR----STGKKRTIPIIVRVSDINDN 138 Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQM----QFSI 202 P+F Y V+V E V + I+A D D G N + Y I G+ ++S Sbjct: 139 APRFMNTPYEVTVPESTPV-GTTIFRNIQALDKDAGVNGLVEYFIAEGSPNSTNVEKYSA 197 Query: 203 DSLS---------GDVSLVKTLDYEQVRSYRLVIRAQD---GGSPSRSNTTQLLINIRDV 250 D G V++ KTLD+E++++Y L I A D + S+TT L +NI D Sbjct: 198 DGYGTFAISFPHQGQVTVAKTLDFEKIQTYYLTIVASDRARNTADRLSSTTTLTVNIADS 257 Query: 251 NDNAPRFYTS--------LFQESVSENVPIGYSI-------VRVQAYDADEGVNAELTYT 295 ND P F S S +VP G + R+QA D D +N+ + Y+ Sbjct: 258 NDLDPSFIYSGCVSLDGACINPEYSASVPAGSLLGVLTVLPERIQAVDLDT-INSPIRYS 316 Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD-GGDPPRSATATXXX 354 GN ID +G + + +D T KY ++V A + P R TA Sbjct: 317 FA-SGMPGNYADYFQIDESTGVLKQTKAVDTSTAKKYDIIVKAEEVSPGPQRFTTAKLEI 375 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPV-------VTLTATDAD-EDNRLHYEITGG 406 Q E + E+ P GT V ++ TDAD D+ + Sbjct: 376 FVKPVDANPPVISSSQAEGYVDENSPIGTRVLDAHGNPISFMTTDADLSDSDPKPDYIYE 435 Query: 407 NTRGRFSITSQNGRGLITVAQ---PLDFKQERRYVLTVSATD--SGGRSDTAMVQINITD 461 T F++T G G++ V + D R+ V A + + S + +++ D Sbjct: 436 LTTPSFNVT---GDGILVVNEENLDRDPPAPGRFKFQVVAREPRTNAASAPLSLTVHLRD 492 Query: 462 ANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521 N+ AP + D V V+ATD+D G NA +TYS+ +SN + Sbjct: 493 VNDNAPKLAMVAPISITAGDQSESRLVTQVTATDNDEGPNAVVTYSI-YHVSNNGI---- 547 Query: 522 QQFVINPQTGAI-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV-DVNDNEP 579 Q+F IN TG I T +LL E Y +TV A D G LS VE+SV N P Sbjct: 548 QKFTINATTGEIRTQGRLLAGEQ---YSITVQATDIG--GLSSQAIVEVSVTPGPNTKPP 602 Query: 580 VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639 F++ +Y + E A + ++V+ V A D + N + Y + + F + SGVI Sbjct: 603 RFQKPIYEVQVSEGAEINSTVTVVHAEDPE---NDAVVYSI-ISGNDLRQFAVGQESGVI 658 Query: 640 RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS-E 698 + LDRES+ + L A D G SS+ V+IK+ DIND P FE+ L + E Sbjct: 659 IVIRKLDRESLTRYQLILKAEDTG--GLSSSATVNIKVTDINDKNPEFEASTLPYVFQVE 716 Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758 ++G + A D DEG NA + YSI F++ G E++T +LDYE Sbjct: 717 EGKAQASVGVVHATDADEGINAEITYSI---PTDIPFTINATSG----EILTAKELDYEQ 769 Query: 759 PRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN--NYKDCFPVGPF 813 +Y+ V+ A A V ++V D+ D P D +I + ++ F V Sbjct: 770 -LNEYKFVVTAKDGAPDARLGTASVTVMVLDLPDEVPKFSDARIDVHIPENEENFLV--- 825 Query: 814 GRVPAYDADVTDKLQYRILSGNNANLILLNETTGSM 849 V A+D D ++ Y +L NA L ++E +G + Sbjct: 826 ATVQAFDPDSMPEITY-VLRKGNAELFKVSEKSGEV 860 Score = 183 bits (446), Expect = 5e-44 Identities = 188/700 (26%), Positives = 306/700 (43%), Gaps = 72/700 (10%) Query: 29 EASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQD 88 E SV G ++ + + + AE+ T+ +V A+ +PE+ Sbjct: 590 EVSVTPGPNTKPPRFQKPIYEVQVSEGAEINSTVTVVHAE--DPENDAVVYSIISGNDLR 647 Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 F + SG ++ LDRE + RY +++KA D LSS+AT+++ + D ND P Sbjct: 648 QFAVGQESGVIIVIRKLDRESLTRYQLILKAEDTGG-----LSSSATVNIKVTDINDKNP 702 Query: 149 QFSEKT--YTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206 +F T Y V+E + + + ATDAD G N+ I Y+I T + F+I++ S Sbjct: 703 EFEASTLPYVFQVEEGKAQAS---VGVVHATDADEGINAEITYSI---PTDIPFTINATS 756 Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266 G++ K LDYEQ+ Y+ V+ A+DG +R T + + + D+ D P+F + + Sbjct: 757 GEILTAKELDYEQLNEYKFVVTAKDGAPDARLGTASVTVMVLDLPDEVPKFSDARIDVHI 816 Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326 EN + + VQA+D D E+TY + GN +L + +SG V T LD Sbjct: 817 PENEE-NFLVATVQAFDPDS--MPEITYVLR----KGNAEL-FKVSEKSGEVRTIKGLDY 868 Query: 327 ETQAKYQLLV-TATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 E+Q ++QL + T + G+ P T F+ V + +D+ GT + Sbjct: 869 ESQKQHQLTIGTIENDGNGP-GDTILLVVDVEDRNDLPPRFITVPDPVTVNDDQGIGTII 927 Query: 386 VTLTATDAD---EDNRLHYEITG-GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441 TL A D D N + YEI G G F + G + + L +++ Y + + Sbjct: 928 ATLPAIDGDGTSPGNVVRYEIVGRGKAPKYFQVDPDT--GAVRIRDELRKEEDTEYQVDI 985 Query: 442 SATDSG--GRSDTAMVQINI---TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496 A D G S A +++++ + N +N + + IG S T S Sbjct: 986 RAYDLGEPQLSSVAPLRVDVHHLLSSGNNEIKLDNKLESGTGMSSESIGLAFSDDSYTTS 1045 Query: 497 -----DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL-----------LD 540 + ++ ++S+ S + +FV G + LD Sbjct: 1046 VPESMEANSTLKLIQIVNSKTSGDGPPAFRCEFVSGNGGGIFNLSSADHGCNLLLIQPLD 1105 Query: 541 RETMSGY--LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF-------KQQLYTANIM 591 E S Y L +T+ V L DTT VEI V D NDN P F +Q + + Sbjct: 1106 FENKSSYSLQLRLTSHRYFVNPLKDTTSVEIIVQDENDNAPEFEFNRLRGQQDTFYTVVT 1165 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDR---EEGSFVIDPASGVIRTNKALD 646 E+ V T++ QV ATD D G G + Y L D ++R F++ +GV+RT K Sbjct: 1166 EEMDVDTTILQVRATDRDSGKFGTVRYTLYDDDENRVNMPTSFFMMSEDTGVLRTAKHFK 1225 Query: 647 RES--VATHDLKAVAIDG---GTPPQSSTVIVHIKIEDIN 681 E+ T ++A DG G+ + ++V+ K+ DIN Sbjct: 1226 NENDFPLTFLVEARDSDGQEQGSHRTRARIVVN-KLADIN 1264 Score = 156 bits (379), Expect = 7e-36 Identities = 188/742 (25%), Positives = 319/742 (42%), Gaps = 75/742 (10%) Query: 90 FRIDGRSGALLTRASLDREKVA--RYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 F + G ++ +LDR+ A R+ V A + P ++ S+ ++ V++ D NDN Sbjct: 441 FNVTGDGILVVNEENLDRDPPAPGRFKFQVVARE---PRTNAASAPLSLTVHLRDVNDNA 497 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI--IGGNTQMQFSIDSL 205 P+ + +S+ +++ ++ ++ ATD D G N+ + Y+I + N +F+I++ Sbjct: 498 PKLA-MVAPISITAG-DQSESRLVTQVTATDNDEGPNAVVTYSIYHVSNNGIQKFTINAT 555 Query: 206 SGDVSLV-KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 +G++ + L EQ Y + ++A D G S ++ + N PRF +++ Sbjct: 556 TGEIRTQGRLLAGEQ---YSITVQATDIGGLSSQAIVEVSVT-PGPNTKPPRFQKPIYEV 611 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 VSE I ++ V A D + N + Y++ +GN + SG + +L Sbjct: 612 QVSEGAEINSTVTVVHAEDPE---NDAVVYSII----SGNDLRQFAVGQESGVIIVIRKL 664 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 DRE+ +YQL++ A D G SAT Y ++ E + + Sbjct: 665 DRESLTRYQLILKAEDTGGLSSSATVNIKVTDINDKNPEFEASTLPYVFQVEEGKAQAS- 723 Query: 385 VVTLTATDADEDNRLHYEITGG-NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443 V + ATDADE ++ EIT T F+I + +G I A+ LD++Q Y V+A Sbjct: 724 VGVVHATDADEG--INAEITYSIPTDIPFTINATSGE--ILTAKELDYEQLNEYKFVVTA 779 Query: 444 TDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501 D R TA V + + D + P F +A + E+ V V A D D Sbjct: 780 KDGAPDARLGTASVTVMVLDLPDEVPKFSDARIDVHIPENEE-NFLVATVQAFDPDS--M 836 Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL 561 +ITY L + + F ++ ++G + T K LD E+ + LT+ + Sbjct: 837 PEITYVLRKG--------NAELFKVSEKSGEVRTIKGLDYESQKQHQLTIGTIENDGNGP 888 Query: 562 SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI-HYEL 620 DT + + V D ND P F + +D +GT ++ + A D D G + YE+ Sbjct: 889 GDTILLVVDVEDRNDLPPRFITVPDPVTVNDDQGIGTIIATLPAIDGDGTSPGNVVRYEI 948 Query: 621 DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST----VIVH-- 674 + + F +DP +G +R L +E + + A D G P SS V VH Sbjct: 949 VGRGKAPKYFQVDPDTGAVRIRDELRKEEDTEYQVDIRAYDLGEPQLSSVAPLRVDVHHL 1008 Query: 675 -------IKIEDINDSPP---------VFESDCLTFYISENSPIGTT---IGEIRAHDPD 715 IK+++ +S F D T + E+ +T I + + Sbjct: 1009 LSSGNNEIKLDNKLESGTGMSSESIGLAFSDDSYTTSVPESMEANSTLKLIQIVNSKTSG 1068 Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---- 771 +GP A G+ F+L + L+ + LD+E+ + Y L +R S Sbjct: 1069 DGPPA-FRCEFVSGNGGGIFNLSS--ADHGCNLLLIQPLDFEN-KSSYSLQLRLTSHRYF 1124 Query: 772 -PPLWNDVRVEILVTDVNDNAP 792 PL + VEI+V D NDNAP Sbjct: 1125 VNPLKDTTSVEIIVQDENDNAP 1146 Score = 52.8 bits (121), Expect = 1e-04 Identities = 61/252 (24%), Positives = 108/252 (42%), Gaps = 35/252 (13%) Query: 645 LDR-ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703 LDR E +H + V+ + + T+ + +++ DIND+ P F + + E++P+G Sbjct: 99 LDRDEENLSHIVFQVSCTTRSTGKKRTIPIIVRVSDINDNAPRFMNTPYEVTVPESTPVG 158 Query: 704 TTI-GEIRAHDPDEGPNAVVHYSI-KGGDDSNSFSLETRQG--------SDKAELVTMVD 753 TTI I+A D D G N +V Y I +G +S + + G + ++ Sbjct: 159 TTIFRNIQALDKDAGVNGLVEYFIAEGSPNSTNVEKYSADGYGTFAISFPHQGQVTVAKT 218 Query: 754 LDYESPRKKYELVI-----RAASPPLWNDVRVEILVTDVNDNAP-------VMKDFQIIF 801 LD+E + Y ++ R + L + + + + D ND P V D I Sbjct: 219 LDFEKIQTYYLTIVASDRARNTADRLSSTTTLTVNIADSNDLDPSFIYSGCVSLDGACIN 278 Query: 802 NNYKDCFPVGPF--------GRVPAYDAD-VTDKLQYRILSG---NNANLILLNETTGSM 849 Y P G R+ A D D + ++Y SG N A+ ++E+TG + Sbjct: 279 PEYSASVPAGSLLGVLTVLPERIQAVDLDTINSPIRYSFASGMPGNYADYFQIDESTGVL 338 Query: 850 TLSPQLNTNVPK 861 + ++T+ K Sbjct: 339 KQTKAVDTSTAK 350 Score = 45.2 bits (102), Expect = 0.026 Identities = 44/176 (25%), Positives = 81/176 (46%), Gaps = 20/176 (11%) Query: 99 LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQF-------S 151 LL LD E + Y++ ++ T V+ L T ++ + + D+NDN P+F Sbjct: 1098 LLLIQPLDFENKSSYSLQLRLTSHRYFVNP-LKDTTSVEIIVQDENDNAPEFEFNRLRGQ 1156 Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG---GNTQMQFSIDSLSGD 208 + T+ V E++ V + I +++ATD D G +RY + M S +S D Sbjct: 1157 QDTFYTVVTEEMDV--DTTILQVRATDRDSGKFGTVRYTLYDDDENRVNMPTSFFMMSED 1214 Query: 209 VSLVKTLDY---EQVRSYRLVIRAQDG-GSPSRSNTT--QLLIN-IRDVNDNAPRF 257 +++T + E ++ A+D G S+ T ++++N + D+N A F Sbjct: 1215 TGVLRTAKHFKNENDFPLTFLVEARDSDGQEQGSHRTRARIVVNKLADINRMALSF 1270 >UniRef50_O60245 Cluster: Protocadherin-7 precursor; n=52; Euteleostomi|Rep: Protocadherin-7 precursor - Homo sapiens (Human) Length = 1069 Score = 245 bits (600), Expect = 1e-62 Identities = 177/590 (30%), Positives = 282/590 (47%), Gaps = 35/590 (5%) Query: 173 KIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVK-TLDYEQVRSYRLVIRAQD 231 ++ A++ G N R ++ Q+ + D +VK LD EQ SY L +R +D Sbjct: 225 RLDASEGGGGTNPGGRSSVF--ELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRD 282 Query: 232 GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE 291 GG P RS+ L + I DVNDN+PRF S+++ ++EN G I++++A D D GVN + Sbjct: 283 GGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQ 342 Query: 292 LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 + Y T +V + +D SGW+ ++DRE + + V A D G PP++ AT Sbjct: 343 IEYVFGAA--TESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKAT 400 Query: 352 XXXXXXXXXXXXXXF-------MPGQYEV-ELAEDEPPGTPVVTLTATDADE-DNRLHYE 402 +P + V +AED TP+ + +D D+ +N + Sbjct: 401 VVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTC 460 Query: 403 ITGGNTRGRFSITS-----QNGRG-LITVAQPLDFKQERRYVLTVSATDSGGRSDTA--M 454 G+ + S QN + + + PLD++ R + + + A DSG S ++ Sbjct: 461 TVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSKNS 520 Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 + + + D N+ P+F + E+ G V V ATD+D G NA+I YSL S + Sbjct: 521 LIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMG 580 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 F I+P +G I N +LDRE Y V A+D G+P L +T V + V D Sbjct: 581 --------IFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADK 632 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634 NDN+P F Q ++T + E+ + V V DAD G N + + + F I+ Sbjct: 633 NDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYI---EENNNIFSIEN 689 Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694 +G I + + DRE T+ + A+DGG PP+S+T V + + D ND+ P Sbjct: 690 DTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLPKNIS 749 Query: 695 Y--ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 Y + +S + T + + A D D+G NA ++YSI GG+ F ++ G Sbjct: 750 YTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSG 799 Score = 232 bits (567), Expect = 1e-58 Identities = 171/566 (30%), Positives = 256/566 (45%), Gaps = 22/566 (3%) Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381 G LDRE + Y+L + DGGDPPRS+ A F YE +LAE+ P Sbjct: 264 GALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAENSAP 323 Query: 382 GTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL 439 GTP++ L A D D + ++ Y R + G ++V +D ++ + Sbjct: 324 GTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREEVNQLRF 383 Query: 440 TVSATDSGG--RSDTAMVQINITDANNYAPVFE-----NAPY---TASVFEDAPIGTTVL 489 TV A D G ++D A V +NI D N+ P E P A+V ED + T + Sbjct: 384 TVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIA 443 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 +V +D D G N +T ++ ++ + D + N + + T+ LD E + + Sbjct: 444 LVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNV 503 Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 + A D G PSLS + + V D NDN P+F Q + E+ + G V+ V ATDAD Sbjct: 504 VIVAVDSGSPSLSSKNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDAD 563 Query: 610 VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669 G N I Y LD G F IDP SG I N LDRE ++ K A D G P Sbjct: 564 SGKNAEIAYSLD--SSVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQG 621 Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729 + V +++ D ND+ P F D TFY+ EN + +G + D D+G NA + I+ Sbjct: 622 STTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIE-- 679 Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVND 789 +++N FS+E G+ + + D ++++ + PP V + V D ND Sbjct: 680 ENNNIFSIENDTGTIYSTM--SFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDEND 737 Query: 790 NAP-VMKDFQIIFNNYKDCFPVGP-FGRVPAYDAD--VTDKLQYRILSGNNANLILLNET 845 NAP V I + V V A D+D + L Y I+ GN L ++ T Sbjct: 738 NAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPT 797 Query: 846 TGSMTLSPQLNTNVPKLATMEVSVTD 871 +G ++L +L L + V V D Sbjct: 798 SGVVSLVGKLTQKHYGLHRLVVQVND 823 Score = 227 bits (555), Expect = 3e-57 Identities = 182/596 (30%), Positives = 262/596 (43%), Gaps = 57/596 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ + D ND+SP FE YEA + E ++ GT +L L+A D D+G N ++EY T Sbjct: 295 RVLITDVNDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATES- 353 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 V+ + R+D SG L +DRE+V + V A D+ P Sbjct: 354 ----------------VRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPK-- 395 Query: 130 LSSTATIHVNIIDDNDNYPQFSE--------KTYTVSVDEDISVTDNPVIAKIKATDADV 181 + AT+ +NI D+NDN P K +V ED+ V D P IA ++ +D D Sbjct: 396 -TDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLV-DTP-IALVQVSDRDQ 452 Query: 182 GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVK-------TLDYEQVRSYRLVIRAQDGGS 234 G N + ++G GD + K LDYE R + +VI A D GS Sbjct: 453 GENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGS 512 Query: 235 PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294 PS S+ L++ + D NDN P F S+ + EN G + V A DAD G NAE+ Y Sbjct: 513 PSLSSKNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAY 572 Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354 ++ D G IDP SG + + LDRE +Y+ V A D G P + T Sbjct: 573 SL-DSSVMG----IFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIV 627 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSI 414 FM + + E+ P +PV +T DAD+ + FSI Sbjct: 628 QVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSI 687 Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVF--- 469 +N G I D + + Y V A D G RS TA V + + D N+ AP Sbjct: 688 --ENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTVTLP 745 Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 +N YT + + + T V V ATDSD GINA + YS+ + + F I+P Sbjct: 746 KNISYTL-LPPSSNVRTVVATVLATDSDDGINADLNYSIVG-------GNPFKLFEIDPT 797 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585 +G ++ L ++ + L V D G PS S TT V + V + N Q+ Sbjct: 798 SGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTVVHVFVNESVSNATAIDSQI 853 Score = 220 bits (538), Expect = 4e-55 Identities = 177/601 (29%), Positives = 274/601 (45%), Gaps = 39/601 (6%) Query: 99 LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158 L+ + +LDRE+ Y + ++ D P SS A + V I D NDN P+F + Y Sbjct: 260 LIVKGALDREQRDSYELTLRVRDGGDPPR---SSQAILRVLITDVNDNSPRFEKSVYEAD 316 Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ---FSIDSLSGDVSLVKTL 215 + E+ S P++ +++A D DVG N I Y + G T+ +D SG +S++ + Sbjct: 317 LAEN-SAPGTPIL-QLRAADLDVGVNGQIEY-VFGAATESVRRLLRLDETSGWLSVLHRI 373 Query: 216 DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE--------SVS 267 D E+V R + A+D G P +++ +++NI+D NDN P +V+ Sbjct: 374 DREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVA 433 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDK---DYTGNVDLPITIDPRSGWVYTSGQL 324 E+V + I VQ D D+G N +T T+ D + + +++TS L Sbjct: 434 EDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPL 493 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 D E ++ +++ A D G P S+ + F EV E+ PG Sbjct: 494 DYEATREFNVVIVAVDSGSPSLSSKNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGER 553 Query: 385 VVTLTATDADEDNRLHYEIT-GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443 V T+ ATDAD + + G F+I +G L+ LD +Q RY V+A Sbjct: 554 VATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTV--LDREQTDRYEFKVNA 611 Query: 444 TDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501 D G + V + + D N+ P F +T V E+ + V +V+ D+D G N Sbjct: 612 KDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRN 671 Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL 561 A++ SL E +N F I TG I + DRE + Y V A DGG P Sbjct: 672 AEM--SLYIEENNNI-------FSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPR 722 Query: 562 SDTTDVEISVVDVNDNEPVF---KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618 S T V + V+D NDN P K YT + + V T V+ V ATD+D G+N ++Y Sbjct: 723 SATATVSLFVMDENDNAPTVTLPKNISYTL-LPPSSNVRTVVATVLATDSDDGINADLNY 781 Query: 619 ELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678 + + + F IDP SGV+ L ++ H L D G P QS+T +VH+ + Sbjct: 782 SIVGGNPFK-LFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTVVHVFVN 840 Query: 679 D 679 + Sbjct: 841 E 841 Score = 176 bits (429), Expect = 6e-42 Identities = 138/473 (29%), Positives = 217/473 (45%), Gaps = 38/473 (8%) Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480 + V LD +Q Y LT+ D G RS A++++ ITD N+ +P FE + Y A + E Sbjct: 260 LIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADLAE 319 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 ++ GT +L + A D DVG+N QI Y + + E+V + ++ +G ++ +D Sbjct: 320 NSAPGTPILQLRAADLDVGVNGQIEYVFGA--ATESVR---RLLRLDETSGWLSVLHRID 374 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY--------TANIME 592 RE ++ TV ARD G P +D V +++ D NDN P + + AN+ E Sbjct: 375 REEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAE 434 Query: 593 DALVGTSVSQVGATDADVGLNG--------RIHYELDPKDREEGSFVIDPASGVIRTNKA 644 D LV T ++ V +D D G NG + ++L P EG + + T+ Sbjct: 435 DVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ--NKKKYFLHTSTP 492 Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 LD E+ ++ VA+D G+P SS + +K+ D ND+PP+F + Y EN+ G Sbjct: 493 LDYEATREFNVVIVAVDSGSPSLSSKNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGE 552 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764 + + A D D G NA + YS+ DS+ + D +++ LD E +YE Sbjct: 553 RVATVLATDADSGKNAEIAYSL----DSSVMGIFAID-PDSGDILVNTVLDREQT-DRYE 606 Query: 765 LVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY--KDCFPVGPFGRVPAY 819 + A P L V + V D NDN P K Q +F Y ++ P P G V Sbjct: 607 FKVNAKDKGIPVLQGSTTVIVQVADKNDNDP--KFMQDVFTFYVKENLQPNSPVGMVTVM 664 Query: 820 DADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 DAD + + N N+ + TG++ + + T V DG Sbjct: 665 DADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDG 717 Score = 46.0 bits (104), Expect = 0.015 Identities = 25/65 (38%), Positives = 33/65 (50%) Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615 G S D + ++ V+D+NDN P F + T + E+ VGT ATD D G NG Sbjct: 118 GPSQSWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGI 177 Query: 616 IHYEL 620 YEL Sbjct: 178 ERYEL 182 Score = 42.3 bits (95), Expect = 0.19 Identities = 21/56 (37%), Positives = 30/56 (53%) Query: 456 QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE 511 Q+ + D N+ P F + T +V E+ P+GT L+ +ATD D G N Y L E Sbjct: 130 QVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQE 185 Score = 41.5 bits (93), Expect = 0.32 Identities = 20/48 (41%), Positives = 25/48 (52%) Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 DIND+ P F S LT + EN P+GT A D D G N + Y + Sbjct: 135 DINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYEL 182 Score = 40.3 bits (90), Expect = 0.75 Identities = 20/53 (37%), Positives = 27/53 (50%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 Q+ VLD ND++P F +V E GT L ATD+D G+N Y + Sbjct: 130 QVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYEL 182 >UniRef50_Q174A5 Cluster: Cadherin; n=1; Aedes aegypti|Rep: Cadherin - Aedes aegypti (Yellowfever mosquito) Length = 1727 Score = 245 bits (599), Expect = 2e-62 Identities = 243/838 (28%), Positives = 372/838 (44%), Gaps = 87/838 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTL-----KATDQDIGKNAEVEYTIELV 65 I + D ND +P F YE+ + E A T V L + D D G N T +L Sbjct: 134 IIITDVNDETPTFRSHSYESEINENAQENTPVSFLGFSRNEVFDYDQGHNG----TFDLY 189 Query: 66 TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125 L P + + F + + LL D EKV + A + A Sbjct: 190 ----LEPNNGLFEITPSRAVNEATFVLRVKDSTLL-----DYEKVKSMNFTIHAREIAP- 239 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG--A 183 + S ATI V+I D NDN+P+FS+ +Y + E+ V ++ +I+A D D G Sbjct: 240 --EGKHSMATIVVHIRDQNDNFPEFSKASYECYLPENSGV--GALLTQIQAVDVDSGDFG 295 Query: 184 NSAIRYAIIGGNTQMQFSIDSLSGDVSLVK----TLDYEQVRSYRLVIRAQDGGSPSRSN 239 S IR+ + G+ +++ L+G +++ LD E V+ + L I A+D N Sbjct: 296 TSGIRFISLSGSIADLLALNPLTGVITIKAPGGHALDRELVQKHYLTIEARDNLGRGNRN 355 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGV-NAELTYTMT 297 + QL+++I DVNDNAP F S+++ + EN + + ++A DAD G N+E+ + + Sbjct: 356 SVQLVVHILDVNDNAPVFLQSMYEARLMENKLSFETPLVLEARDADLNGTKNSEIKFEIV 415 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRE--TQAKYQ-----LLVTATDGGDPPRSATA 350 + + N TID +SG + +D E T + L V A+D G P S Sbjct: 416 EGQFKDN----FTIDAKSGKLVPLTPIDFELLTSGTFNIRPIFLTVLASDSGVPKLSTKV 471 Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGN 407 F+ Y + E+ P G+P++ + A D D +N + Y I G Sbjct: 472 PVTIHVQDVNDHPPQFLHSVYTQSVPENLPSGSPILEVKAIDKDGSSPNNFIVYRIQSGA 531 Query: 408 TRGRFSITSQNGRGLITVAQPLD----FKQERRYVLTVSATDSG-GRSDT---AMVQINI 459 + +F I+ G + LD + Y L V A D G G V I+I Sbjct: 532 S-DKFVISPDTGIISVATGASLDPDMTDPKTTEYFLNVLALDGGIGEQQLQSFCRVNISI 590 Query: 460 TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG------INAQITYSLSSEIS 513 D NN +P F P T S+ E+ P+GT + A D D +++ + + S E + Sbjct: 591 KDVNNKSPYFLE-PGTISIRENTPVGTYAYRLLANDLDKEPILRYYMDSNTSEARSEEGA 649 Query: 514 NEAVAHHDQ--QFVINPQTGAITTNKLLDRETMS----GYLLTVTARDGGVPSLSDTTDV 567 ++ +D F++N G I KLLDRE + G+++ A + G + TT + Sbjct: 650 LVKLSEYDYLTAFMLNSTDGLIRVIKLLDREKVEIIKLGFIVEDIAAEFGKQTA--TTTL 707 Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD-PKDRE 626 I V D NDN P F+ Y +I E++ G ++ V A D D N I Y L+ PK+ Sbjct: 708 TIVVEDENDNNPKFRNSFYKRSIPENSPHGVTIMSVVADDMDK--NKTIRYSLEGPKEIT 765 Query: 627 EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686 E +D +G I + +D E + A D G PP+SS V I++ D ND+ P Sbjct: 766 E-LLHLDMETGEIVVSNKIDYEIFPWLNFTVRATDSGHPPRSSLAEVFIQVIDENDNNPY 824 Query: 687 FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746 F D F + ENS IGT I I+A DPD G + Y I S FS++ G Sbjct: 825 FPIDTTNFTVYENSMIGTRIATIQALDPDSGAFGKITYLIDRVSASGKFSIDPDTG---- 880 Query: 747 ELVTMVDLDYESPRKKYELVIRA--------ASPPLWNDVR-VEILVTDVNDNAPVMK 795 L+ + D + Y +VI A S N + + I V D NDNAP+++ Sbjct: 881 -LLVVADFLDREKQDSYMIVIEAWDNYQFGYLSGESRNAFKQIFISVLDENDNAPIIQ 937 Score = 233 bits (570), Expect = 5e-59 Identities = 244/902 (27%), Positives = 386/902 (42%), Gaps = 90/902 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D D P F + V E A GTTV +KA D D G N + Y+I Sbjct: 22 VKVKDVEDQPPEFIVASTVIRVPEDAPIGTTVTQVKAIDGDRGVNNRIRYSIS------- 74 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKV-----ARYTVLVKATDQASP 125 + FRIDG G + T LDRE A Y + + AT+Q S Sbjct: 75 -------------RNISSPFRIDGSLGTISTTMKLDREDARNRANAAYILEIVATEQNSK 121 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV----IAKIKATDADV 181 + S I + I D ND P F +Y ++E+ + + PV ++ + D D Sbjct: 122 IKPTPSVRTEITIIITDVNDETPTFRSHSYESEINEN-AQENTPVSFLGFSRNEVFDYDQ 180 Query: 182 GANSAIRYAIIGGNTQMQFSIDSLSGDVSLV------KTLDYEQVRSYRLVIRAQDGGSP 235 G N + N + + + + V LDYE+V+S I A++ Sbjct: 181 GHNGTFDLYLEPNNGLFEITPSRAVNEATFVLRVKDSTLLDYEKVKSMNFTIHAREIAPE 240 Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295 + + ++++IRD NDN P F + ++ + EN +G + ++QA D D G T Sbjct: 241 GKHSMATIVVHIRDQNDNFPEFSKASYECYLPENSGVGALLTQIQAVDVDSGDFG--TSG 298 Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSG----QLDRETQAKYQLLVTATDGGDPPRSATAT 351 + +G++ + ++P +G + LDRE K+ L + A D + Sbjct: 299 IRFISLSGSIADLLALNPLTGVITIKAPGGHALDRELVQKHYLTIEARDNLGRGNRNSVQ 358 Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD----EDNRLHYEITGGN 407 F+ YE L E++ + L A DAD +++ + +EI G Sbjct: 359 LVVHILDVNDNAPVFLQSMYEARLMENKLSFETPLVLEARDADLNGTKNSEIKFEIVEGQ 418 Query: 408 TRGRFSITSQNGRGLITVAQPLDFK-------QERRYVLTVSATDSG--GRSDTAMVQIN 458 + F+I +++G+ + P+DF+ R LTV A+DSG S V I+ Sbjct: 419 FKDNFTIDAKSGK--LVPLTPIDFELLTSGTFNIRPIFLTVLASDSGVPKLSTKVPVTIH 476 Query: 459 ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAV 517 + D N++ P F ++ YT SV E+ P G+ +L V A D D N I Y + S S++ V Sbjct: 477 VQDVNDHPPQFLHSVYTQSVPENLPSGSPILEVKAIDKDGSSPNNFIVYRIQSGASDKFV 536 Query: 518 AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV--PSLSDTTDVEISVVDVN 575 D +I+ TGA + D +T + Y L V A DGG+ L V IS+ DVN Sbjct: 537 ISPDTG-IISVATGASLDPDMTDPKT-TEYFLNVLALDGGIGEQQLQSFCRVNISIKDVN 594 Query: 576 DNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD--REEG----- 628 + P F + T +I E+ VGT ++ A D D R + + + + EEG Sbjct: 595 NKSPYFLEP-GTISIRENTPVGTYAYRLLANDLDKEPILRYYMDSNTSEARSEEGALVKL 653 Query: 629 -------SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP--PQSSTVIVHIKIED 679 +F+++ G+IR K LDRE V L + D Q++T + I +ED Sbjct: 654 SEYDYLTAFMLNSTDGLIRVIKLLDREKVEIIKLGFIVEDIAAEFGKQTATTTLTIVVED 713 Query: 680 INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD-SNSFSLE 738 ND+ P F + I ENSP G TI + A D D+ N + YS++G + + L+ Sbjct: 714 ENDNNPKFRNSFYKRSIPENSPHGVTIMSVVADDMDK--NKTIRYSLEGPKEITELLHLD 771 Query: 739 TRQGSDKAELVTMVDLDYE-SPRKKYEL-VIRAASPPLWNDVRVEILVTDVNDNAPVMKD 796 G E+V +DYE P + + + PP + V I V D NDN P Sbjct: 772 METG----EIVVSNKIDYEIFPWLNFTVRATDSGHPPRSSLAEVFIQVIDENDNNPYFPI 827 Query: 797 FQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQ 854 F Y++ + A D D K+ Y I + + ++ TG + ++ Sbjct: 828 DTTNFTVYENSMIGTRIATIQALDPDSGAFGKITYLIDRVSASGKFSIDPDTGLLVVADF 887 Query: 855 LN 856 L+ Sbjct: 888 LD 889 Score = 215 bits (526), Expect = 1e-53 Identities = 241/915 (26%), Positives = 397/915 (43%), Gaps = 89/915 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +++LD ND++PVF YEA + E S T L L+A D D+ E E+V Sbjct: 361 VHILDVNDNAPVFLQSMYEARLMENKLSFETPLVLEARDADLNGTKNSEIKFEIVEGQ-- 418 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD-- 128 +D F ID +SG L+ +D E + T ++ SD Sbjct: 419 ---------------FKDNFTIDAKSGKLVPLTPIDFELLTSGTFNIRPIFLTVLASDSG 463 Query: 129 --RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA-NS 185 +LS+ + +++ D ND+ PQF YT SV E++ + +P++ ++KA D D + N+ Sbjct: 464 VPKLSTKVPVTIHVQDVNDHPPQFLHSVYTQSVPENLP-SGSPIL-EVKAIDKDGSSPNN 521 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVK--TLDYE----QVRSYRLVIRAQDGGSPSRS- 238 I Y I G + +F I +G +S+ +LD + + Y L + A DGG + Sbjct: 522 FIVYRIQSGASD-KFVISPDTGIISVATGASLDPDMTDPKTTEYFLNVLALDGGIGEQQL 580 Query: 239 -NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG------VNAE 291 + ++ I+I+DVN+ +P ++ S+ EN P+G R+ A D D+ +++ Sbjct: 581 QSFCRVNISIKDVNNKSP-YFLEPGTISIRENTPVGTYAYRLLANDLDKEPILRYYMDSN 639 Query: 292 LTYTMTDKDYTGNVD-----LPITIDPRSGWVYTSGQLDRETQA--KYQLLVTATDGGDP 344 + +++ + ++ G + LDRE K +V Sbjct: 640 TSEARSEEGALVKLSEYDYLTAFMLNSTDGLIRVIKLLDREKVEIIKLGFIVEDIAAEFG 699 Query: 345 PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT 404 ++AT T F Y+ + E+ P G ++++ A D D++ + Y + Sbjct: 700 KQTATTTLTIVVEDENDNNPKFRNSFYKRSIPENSPHGVTIMSVVADDMDKNKTIRYSLE 759 Query: 405 GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDA 462 G G I V+ +D++ TV ATDSG RS A V I + D Sbjct: 760 GPKEITELLHLDME-TGEIVVSNKIDYEIFPWLNFTVRATDSGHPPRSSLAEVFIQVIDE 818 Query: 463 NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522 N+ P F +V+E++ IGT + + A D D G +ITY L +S Sbjct: 819 NDNNPYFPIDTTNFTVYENSMIGTRIATIQALDPDSGAFGKITY-LIDRVSASG------ 871 Query: 523 QFVINPQTGAITTNKLLDRETMSGYLLTVTARDG------GVPSLSDTTDVEISVVDVND 576 +F I+P TG + LDRE Y++ + A D S + + ISV+D ND Sbjct: 872 KFSIDPDTGLLVVADFLDREKQDSYMIVIEAWDNYQFGYLSGESRNAFKQIFISVLDEND 931 Query: 577 NEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL--NGRIHYELDPKDREEGSFVIDP 634 N P+ + + E + + + ATDAD NG I +++ + F+ Sbjct: 932 NAPIIQVPDGCVQVTEFHDIREPLLVLKATDADDPKTGNGLIGFDIIDVAGSDIFFLRQK 991 Query: 635 ASGV--IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC- 691 GV I ++++L+ + L +A D G+PP + + I + D ND P F S Sbjct: 992 ERGVAEIFSSRSLNN-FYGNYSLLIMARDEGSPPNTVNEKIDICVLDFNDHAPEFVSPSS 1050 Query: 692 -LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG--DDSNSFSLETRQGSDKAEL 748 +T I EN+ +GT I ++ A D D GPNA V Y K SFS++ GS + Sbjct: 1051 NITIRIPENATVGTMIIQVMARDNDIGPNAAVRYRFKPDPLGSFRSFSIDEDTGS----I 1106 Query: 749 VTMVDLDYESPRKKYELVIRA----ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY 804 + LD E +K +EL + A PL +D+ + I V +VND P +I N Sbjct: 1107 TLKLPLDRER-QKVHELRVEAYDQGIPTPLSSDLDLTIYVRNVNDYEPQFLVEEISVNFT 1165 Query: 805 KDCFPVGPFGRVP-AYDADVTDKLQ-------YRILSGNNANLILLNETTGSMTLSPQLN 856 + P ++P D D D L Y I+ GN L+ + +T++ +L+ Sbjct: 1166 EHARPGLERRQLPDTIDRDEVDDLDDPPTMVCYFIVYGNENGHFHLDPYSHILTVTKELD 1225 Query: 857 TNVPKLATMEVSVTD 871 T+ V T+ Sbjct: 1226 RESRSNHTLVVKATE 1240 Score = 191 bits (465), Expect = 3e-46 Identities = 191/721 (26%), Positives = 310/721 (42%), Gaps = 71/721 (9%) Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295 + + T LL+ ++DV D P F + V E+ PIG ++ +V+A D D GVN + Y+ Sbjct: 13 TNTGTAALLVKVKDVEDQPPEFIVASTVIRVPEDAPIGTTVTQVKAIDGDRGVNNRIRYS 72 Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE-----TQAKYQLLVTATDGGD---PPRS 347 + + N+ P ID G + T+ +LDRE A Y L + AT+ P S Sbjct: 73 I-----SRNISSPFRIDGSLGTISTTMKLDREDARNRANAAYILEIVATEQNSKIKPTPS 127 Query: 348 ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL-----TATDADEDNRLHYE 402 F YE E+ E+ TPV L D D+ + ++ Sbjct: 128 VRTEITIIITDVNDETPTFRSHSYESEINENAQENTPVSFLGFSRNEVFDYDQGHNGTFD 187 Query: 403 ITGGNTRGRFSITSQNGRGLITV------AQPLDFKQERRYVLTVSATDSG--GRSDTAM 454 + G F IT T + LD+++ + T+ A + G+ A Sbjct: 188 LYLEPNNGLFEITPSRAVNEATFVLRVKDSTLLDYEKVKSMNFTIHAREIAPEGKHSMAT 247 Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD---SDVGINAQITYSLSSE 511 + ++I D N+ P F A Y + E++ +G + + A D D G + SLS Sbjct: 248 IVVHIRDQNDNFPEFSKASYECYLPENSGVGALLTQIQAVDVDSGDFGTSGIRFISLSGS 307 Query: 512 ISNEAVAHHDQQFVINPQTGAITT----NKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567 I++ +NP TG IT LDRE + + LT+ ARD ++ + Sbjct: 308 IAD--------LLALNPLTGVITIKAPGGHALDRELVQKHYLTIEARDNLGRGNRNSVQL 359 Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG--LNGRIHYELDPKDR 625 + ++DVNDN PVF Q +Y A +ME+ L + + A DAD+ N I +E+ + + Sbjct: 360 VVHILDVNDNAPVFLQSMYEARLMENKLSFETPLVLEARDADLNGTKNSEIKFEI-VEGQ 418 Query: 626 EEGSFVIDPASGVIRTNKALDRESVATHD-------LKAVAIDGGTPPQSSTVIVHIKIE 678 + +F ID SG + +D E + + L +A D G P S+ V V I ++ Sbjct: 419 FKDNFTIDAKSGKLVPLTPIDFELLTSGTFNIRPIFLTVLASDSGVPKLSTKVPVTIHVQ 478 Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSL 737 D+ND PP F T + EN P G+ I E++A D D PN + Y I+ G S+ F + Sbjct: 479 DVNDHPPQFLHSVYTQSVPENLPSGSPILEVKAIDKDGSSPNNFIVYRIQSG-ASDKFVI 537 Query: 738 ETRQGSDKAELVTMVDLDYESPR-KKYELVIRA-----ASPPLWNDVRVEILVTDVNDNA 791 G +D D P+ +Y L + A L + RV I + DVN+ + Sbjct: 538 SPDTGIISVATGASLDPDMTDPKTTEYFLNVLALDGGIGEQQLQSFCRVNISIKDVNNKS 597 Query: 792 PVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVTDKLQYRILSGNNANLILLNETTGSMT 850 P + I + ++ PVG + R+ A D D L+Y + ++N G++ Sbjct: 598 PYFLEPGTI--SIRENTPVGTYAYRLLANDLDKEPILRYYM----DSNTSEARSEEGALV 651 Query: 851 LSPQLNTNVPKLATMEVSVTDG-VNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFL 909 + + L ++ TDG + IK + + V +I ++ I TA L Sbjct: 652 KLSEYD----YLTAFMLNSTDGLIRVIKLLDREKVEIIKLGFIVEDIAAEFGKQTATTTL 707 Query: 910 S 910 + Sbjct: 708 T 708 Score = 190 bits (464), Expect = 4e-46 Identities = 190/666 (28%), Positives = 295/666 (44%), Gaps = 62/666 (9%) Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + TA + V + D D P+F + + V ED + + ++KA D D G N+ IRY+ Sbjct: 15 TGTAALLVKVKDVEDQPPEFIVASTVIRVPEDAPI--GTTVTQVKAIDGDRGVNNRIRYS 72 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-----YRLVIRAQDGGS---PSRSNTTQ 242 I N F ID G +S LD E R+ Y L I A + S P+ S T+ Sbjct: 73 I-SRNISSPFRIDGSLGTISTTMKLDREDARNRANAAYILEIVATEQNSKIKPTPSVRTE 131 Query: 243 LLINIRDVNDNAPRF----YTSLFQESVSENVPIGY-SIVRVQAYDADEGVNAELTYTMT 297 + I I DVND P F Y S E+ EN P+ + R + +D D+G N + Sbjct: 132 ITIIITDVNDETPTFRSHSYESEINENAQENTPVSFLGFSRNEVFDYDQGHNGTFDLYLE 191 Query: 298 DKDYTGNVDLPITIDPRSG--WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355 + + ++ + V S LD E + A + + + AT Sbjct: 192 PNNGLFEITPSRAVNEATFVLRVKDSTLLDYEKVKSMNFTIHAREIAPEGKHSMATIVVH 251 Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS-I 414 F YE L E+ G + + A D D + I + G + + Sbjct: 252 IRDQNDNFPEFSKASYECYLPENSGVGALLTQIQAVDVDSGDFGTSGIRFISLSGSIADL 311 Query: 415 TSQNG-RGLITVAQP----LDFKQERRYVLTVSATDSGGRSDTAMVQ--INITDANNYAP 467 + N G+IT+ P LD + +++ LT+ A D+ GR + VQ ++I D N+ AP Sbjct: 312 LALNPLTGVITIKAPGGHALDRELVQKHYLTIEARDNLGRGNRNSVQLVVHILDVNDNAP 371 Query: 468 VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV-AHHDQQFVI 526 VF + Y A + E+ T LV+ A D+D + + +SEI E V F I Sbjct: 372 VFLQSMYEARLMENKLSFETPLVLEARDAD------LNGTKNSEIKFEIVEGQFKDNFTI 425 Query: 527 NPQTGAITTNKLLDRETMSG-------YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP 579 + ++G + +D E ++ LTV A D GVP LS V I V DVND+ P Sbjct: 426 DAKSGKLVPLTPIDFELLTSGTFNIRPIFLTVLASDSGVPKLSTKVPVTIHVQDVNDHPP 485 Query: 580 VFKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDPASGV 638 F +YT ++ E+ G+ + +V A D D N I Y + + FVI P +G+ Sbjct: 486 QFLHSVYTQSVPENLPSGSPILEVKAIDKDGSSPNNFIVYRI--QSGASDKFVISPDTGI 543 Query: 639 I--RTNKALDRE----SVATHDLKAVAIDGGTPPQ--SSTVIVHIKIEDINDSPPVFESD 690 I T +LD + + L +A+DGG Q S V+I I+D+N+ P F + Sbjct: 544 ISVATGASLDPDMTDPKTTEYFLNVLALDGGIGEQQLQSFCRVNISIKDVNNKSPYF-LE 602 Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750 T I EN+P+GT + A+D D+ P ++ Y + DSN+ + +G+ LV Sbjct: 603 PGTISIRENTPVGTYAYRLLANDLDKEP--ILRYYM----DSNTSEARSEEGA----LVK 652 Query: 751 MVDLDY 756 + + DY Sbjct: 653 LSEYDY 658 Score = 137 bits (331), Expect = 5e-30 Identities = 176/694 (25%), Positives = 284/694 (40%), Gaps = 64/694 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V+D ND++P F + +V E + GT + T++A D D G ++ Y I+ V+A Sbjct: 813 IQVIDENDNNPYFPIDTTNFTVYENSMIGTRIATIQALDPDSGAFGKITYLIDRVSAS-- 870 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD--QASPVS- 127 F ID +G L+ LDREK Y ++++A D Q +S Sbjct: 871 -----------------GKFSIDPDTGLLVVADFLDREKQDSYMIVIEAWDNYQFGYLSG 913 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD--VGANS 185 + ++ I ++++D+NDN P V V E + + P++ +KATDAD N Sbjct: 914 ESRNAFKQIFISVLDENDNAPIIQVPDGCVQVTEFHDIRE-PLLV-LKATDADDPKTGNG 971 Query: 186 AIRYAIIG-GNTQMQFSIDSLSGDVSLVKTLDYEQVR-SYRLVIRAQDGGSPSRSNTTQL 243 I + II + + F G + + +Y L+I A+D GSP + ++ Sbjct: 972 LIGFDIIDVAGSDIFFLRQKERGVAEIFSSRSLNNFYGNYSLLIMARDEGSPPNTVNEKI 1031 Query: 244 LINIRDVNDNAPRFYT--SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 I + D ND+AP F + S + EN +G I++V A D D G NA + Y D Sbjct: 1032 DICVLDFNDHAPEFVSPSSNITIRIPENATVGTMIIQVMARDNDIGPNAAVRYRFKP-DP 1090 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSATATXXXXXXXXX 360 G+ +ID +G + LDRE Q ++L V A D G P P S+ Sbjct: 1091 LGSFR-SFSIDEDTGSITLKLPLDRERQKVHELRVEAYDQGIPTPLSSDLDLTIYVRNVN 1149 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTAT-DADEDNRLHYEITGGNTRGRFSITSQNG 419 F+ + V E PG L T D DE + ++ T + I N Sbjct: 1150 DYEPQFLVEEISVNFTEHARPGLERRQLPDTIDRDEVD----DLDDPPTMVCYFIVYGNE 1205 Query: 420 RGLITVAQPLDFKQERRYVLTVSAT-DSGGRSDTAMVQINITDANNYAPVFE-NAPYTAS 477 G + P ++LTV+ D RS+ +V D N P + P + Sbjct: 1206 NGHFHL-DPYS------HILTVTKELDRESRSNHTLVVKATEDCINTPPSINLSRPEAIA 1258 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 + + P T + I S + I+ + GA++ Sbjct: 1259 LQKPTPFKYHQRTTKPTTAVASQYVSIYDRYKKSRSFDTPGTE-----IDIKQGAVSWQS 1313 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVE--ISVVDVNDNEPVFKQQLYTANIMEDAL 595 D S + G + +D T V I V D+NDN PVF Q+++T + + Sbjct: 1314 DADSAPSSLLMPRFEKYTGQLFYHNDNTLVRVLIHVQDINDNPPVFIQKIFTGGVTTSTV 1373 Query: 596 VGTSVSQVGATDADVGLNGRI-HYELD--PKDREEG-------SFVIDPASGVIRTNKAL 645 GT ++ A D D G NG++ +Y++ K EG F++D +G ++ N Sbjct: 1374 FGTQFLKLTAIDRDHGANGQVSYYQIGDIKKTLTEGLENVQKPPFLVDRRTGAVQLNFDP 1433 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679 + D K +A D + V +++ ED Sbjct: 1434 QKGMKGYFDFKVLANDSAGHSDEAHVFIYLLRED 1467 Score = 72.5 bits (170), Expect = 2e-10 Identities = 67/239 (28%), Positives = 111/239 (46%), Gaps = 29/239 (12%) Query: 2 SVPFCIHQQIN--VLDCNDHSPVFEMQQYEASVR--EGASSGTTVLTLKATDQDIGKNAE 57 S P ++++I+ VLD NDH+P F ++R E A+ GT ++ + A D DIG NA Sbjct: 1022 SPPNTVNEKIDICVLDFNDHAPEFVSPSSNITIRIPENATVGTMIIQVMARDNDIGPNAA 1081 Query: 58 VEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLV 117 V Y + P+ F ID +G++ + LDRE+ + + V Sbjct: 1082 VRYRFK--------PDPLGSFRS---------FSIDEDTGSITLKLPLDRERQKVHELRV 1124 Query: 118 KATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE----DISVTDNP-VIA 172 +A DQ P LSS + + + + ND PQF + +V+ E + P I Sbjct: 1125 EAYDQGIPTP--LSSDLDLTIYVRNVNDYEPQFLVEEISVNFTEHARPGLERRQLPDTID 1182 Query: 173 KIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD 231 + + D D + + Y I+ GN F +D S +++ K LD E ++ LV++A + Sbjct: 1183 RDEVDDLD-DPPTMVCYFIVYGNENGHFHLDPYSHILTVTKELDRESRSNHTLVVKATE 1240 Score = 44.0 bits (99), Expect = 0.061 Identities = 47/173 (27%), Positives = 74/173 (42%), Gaps = 11/173 (6%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS- 513 V I++ D N+ PVF +T V GT L ++A D D G N Q++Y +I Sbjct: 1345 VLIHVQDINDNPPVFIQKIFTGGVTTSTVFGTQFLKLTAIDRDHGANGQVSYYQIGDIKK 1404 Query: 514 --NEAVAH-HDQQFVINPQTGAITTNKLLDRETMSGYL-LTVTARDGGVPSLSDTTDVEI 569 E + + F+++ +TGA+ N ++ M GY V A D SD V I Sbjct: 1405 TLTEGLENVQKPPFLVDRRTGAVQLN-FDPQKGMKGYFDFKVLANDSA--GHSDEAHVFI 1461 Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSV-SQVGATDADVGLNGRIHYELD 621 ++ D F +L + E V S V ++ ++ + RIH D Sbjct: 1462 YLLR-EDQRVKFVLRLQPTEVREKIFTFRDVLSNVSSSIVNID-DFRIHENRD 1512 Score = 41.5 bits (93), Expect = 0.32 Identities = 21/57 (36%), Positives = 32/57 (56%) Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 ++ V V I ++DIND+PPVF T ++ ++ GT ++ A D D G N V Y Sbjct: 1340 NTLVRVLIHVQDINDNPPVFIQKIFTGGVTTSTVFGTQFLKLTAIDRDHGANGQVSY 1396 >UniRef50_UPI0000E81FAF Cluster: PREDICTED: similar to Protocadherin beta 1 precursor (PCDH-beta1); n=1; Gallus gallus|Rep: PREDICTED: similar to Protocadherin beta 1 precursor (PCDH-beta1) - Gallus gallus Length = 926 Score = 244 bits (598), Expect = 2e-62 Identities = 182/591 (30%), Positives = 276/591 (46%), Gaps = 29/591 (4%) Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV----RSYRLVIRAQDGGSPSRSNT 240 +A + ++ ++ F +D SG +++ +TLD E++ S L+ + N Sbjct: 143 AARKARVVSEGSEQHFRLDPHSGVLTVTETLDRERICPHSESCALLFKL------FFENP 196 Query: 241 TQLL---INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297 QL+ + +RDVND++P F +SE G +A D D G+N Y+++ Sbjct: 197 VQLIRGEVEVRDVNDHSPVFPQKEMVLDISETASPGLRFPLEKAQDEDVGINGLQNYSLS 256 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357 + + + LDRE Q + L++TATDGG PPRS TA Sbjct: 257 PNSHFSLALGRGKDGDKYAELVLQRPLDREEQRELHLVLTATDGGSPPRSGTAQVRVVVL 316 Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSIT 415 F YE+ +AE+ PPG VV ++A D DE + ++ Y + R R + Sbjct: 317 DANDNMPVFSREVYEIRVAENSPPGQLVVRVSAADPDEGSNGKVRYAFSQTTERTRQLFS 376 Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYT 475 G G I V LD + + + + V ATD GG S V + + D N+++P F Sbjct: 377 LDPGTGEIRVRGNLDCEDAKNHEMVVRATDGGGLSAHCRVHVEVRDVNDHSPEFPEKDVV 436 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 V E A GT + +A D DVGIN YSLS S+ ++A ++ + + Sbjct: 437 LDVPETASPGTRFPLEAARDKDVGINGLQDYSLSPN-SHFSLALETEKR--GGKYAELVL 493 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 K LDRE L +TA DGG PS S T V + V+D NDN PVF +++Y + E++ Sbjct: 494 QKPLDREEQRELHLVLTATDGGSPSRSGTAQVRVVVLDANDNMPVFSREVYEVRVAENSP 553 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGS---FVIDPASGVIRTNKALDRESVAT 652 G V +V A D D G G++ Y EGS F ++ SGVIR + LD E + Sbjct: 554 PGQLVVRVSAADPDEGSYGKVRYAFS--QTTEGSRQLFDLNADSGVIRVSGKLDFEEAKS 611 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 H+L A DGG S+ VH+++ D+ND+ P ++ I E++P T + + Sbjct: 612 HELVVRATDGGG--LSAHCRVHVEVLDVNDNAPEMALSSVSASIPEDAPPRTVVALLSVR 669 Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY 763 D D G N +I+G FSL T ++ EL T LD E+ Y Sbjct: 670 DRDSGDNGRTECAIEG---DVPFSL-TAAFANHYELRTSAALDRETTALGY 716 Score = 225 bits (550), Expect = 1e-56 Identities = 168/552 (30%), Positives = 257/552 (46%), Gaps = 46/552 (8%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 I ++ V D NDHSPVF ++ + E AS G KA D+D+G N Y Sbjct: 200 IRGEVEVRDVNDHSPVFPQKEMVLDISETASPGLRFPLEKAQDEDVGINGLQNY------ 253 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASP 125 +L+P DG + L+ + LDRE+ +++ ATD SP Sbjct: 254 --SLSPNSHFSLALGRGK--------DGDKYAELVLQRPLDREEQRELHLVLTATDGGSP 303 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 S TA + V ++D NDN P FS + Y + V E + ++ ++ A D D G+N Sbjct: 304 PR---SGTAQVRVVVLDANDNMPVFSREVYEIRVAE--NSPPGQLVVRVSAADPDEGSNG 358 Query: 186 AIRYAI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 +RYA T+ FS+D +G++ + LD E +++ +V+RA DGG S ++ Sbjct: 359 KVRYAFSQTTERTRQLFSLDPGTGEIRVRGNLDCEDAKNHEMVVRATDGGGLSAH--CRV 416 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 + +RDVND++P F V E G A D D G+N Y+++ + Sbjct: 417 HVEVRDVNDHSPEFPEKDVVLDVPETASPGTRFPLEAARDKDVGINGLQDYSLSPNSH-- 474 Query: 304 NVDLPITIDPRSG---WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 L + + R G + LDRE Q + L++TATDGG P RS TA Sbjct: 475 -FSLALETEKRGGKYAELVLQKPLDREEQRELHLVLTATDGGSPSRSGTAQVRVVVLDAN 533 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN----RLHYEITGGNTRGRFSITS 416 F YEV +AE+ PPG VV ++A D DE + R + T +R F + + Sbjct: 534 DNMPVFSREVYEVRVAENSPPGQLVVRVSAADPDEGSYGKVRYAFSQTTEGSRQLFDLNA 593 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA 476 + G+I V+ LDF++ + + L V ATD GG S V + + D N+ AP + +A Sbjct: 594 DS--GVIRVSGKLDFEEAKSHELVVRATDGGGLSAHCRVHVEVLDVNDNAPEMALSSVSA 651 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 S+ EDAP T V ++S D D G N + ++ ++ A + + T+ Sbjct: 652 SIPEDAPPRTVVALLSVRDRDSGDNGRTECAIEGDVPFSLTAAFANHY-------ELRTS 704 Query: 537 KLLDRETMS-GY 547 LDRET + GY Sbjct: 705 AALDRETTALGY 716 Score = 223 bits (546), Expect = 4e-56 Identities = 186/605 (30%), Positives = 276/605 (45%), Gaps = 40/605 (6%) Query: 90 FRIDGRSGALLTRASLDREKVARYT---VLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146 FR+D SG L +LDRE++ ++ L+ +PV V + D ND+ Sbjct: 158 FRLDPHSGVLTVTETLDRERICPHSESCALLFKLFFENPVQ-----LIRGEVEVRDVNDH 212 Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIA--KIKATDADVGANSAIRYAIIGGNTQMQFSID- 203 P F +K + DIS T +P + KA D DVG N Y++ N+ ++ Sbjct: 213 SPVFPQKEMVL----DISETASPGLRFPLEKAQDEDVGINGLQNYSL-SPNSHFSLALGR 267 Query: 204 SLSGD----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259 GD + L + LD E+ R LV+ A DGGSP RS T Q+ + + D NDN P F Sbjct: 268 GKDGDKYAELVLQRPLDREEQRELHLVLTATDGGSPPRSGTAQVRVVVLDANDNMPVFSR 327 Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319 +++ V+EN P G +VRV A D DEG N ++ Y + T ++DP +G + Sbjct: 328 EVYEIRVAENSPPGQLVVRVSAADPDEGSNGKVRYAFSQT--TERTRQLFSLDPGTGEIR 385 Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE 379 G LD E ++++V ATDGG SA F +++ E Sbjct: 386 VRGNLDCEDAKNHEMVVRATDGGG--LSAHCRVHVEVRDVNDHSPEFPEKDVVLDVPETA 443 Query: 380 PPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQNGRGL---ITVAQPLDFKQER 435 PGT A D D N L N+ ++ ++ G + + +PLD +++R Sbjct: 444 SPGTRFPLEAARDKDVGINGLQDYSLSPNSHFSLALETEKRGGKYAELVLQKPLDREEQR 503 Query: 436 RYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 L ++ATD G RS TA V++ + DAN+ PVF Y V E++P G V+ VSA Sbjct: 504 ELHLVLTATDGGSPSRSGTAQVRVVVLDANDNMPVFSREVYEVRVAENSPPGQLVVRVSA 563 Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553 D D G ++ Y+ S Q F +N +G I + LD E + L V A Sbjct: 564 ADPDEGSYGKVRYAFSQTTEGSR-----QLFDLNADSGVIRVSGKLDFEEAKSHELVVRA 618 Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613 DGG LS V + V+DVNDN P +A+I EDA T V+ + D D G N Sbjct: 619 TDGG--GLSAHCRVHVEVLDVNDNAPEMALSSVSASIPEDAPPRTVVALLSVRDRDSGDN 676 Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673 GR ++ D +RT+ ALDRE+ A ++ A T P+ T+ Sbjct: 677 GRTECAIE-GDVPFSLTAAFANHYELRTSAALDRETTALGYYRSEACH--TMPKKETLAA 733 Query: 674 HIKIE 678 + ++ Sbjct: 734 YAGVQ 738 Score = 190 bits (464), Expect = 4e-46 Identities = 129/378 (34%), Positives = 182/378 (48%), Gaps = 16/378 (4%) Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480 + + +PLD +++R L ++ATD G RS TA V++ + DAN+ PVF Y V E Sbjct: 277 LVLQRPLDREEQRELHLVLTATDGGSPPRSGTAQVRVVVLDANDNMPVFSREVYEIRVAE 336 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 ++P G V+ VSA D D G N ++ Y+ S + Q F ++P TG I LD Sbjct: 337 NSPPGQLVVRVSAADPDEGSNGKVRYAFS-----QTTERTRQLFSLDPGTGEIRVRGNLD 391 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 E + + V A DGG LS V + V DVND+ P F ++ ++ E A GT Sbjct: 392 CEDAKNHEMVVRATDGG--GLSAHCRVHVEVRDVNDHSPEFPEKDVVLDVPETASPGTRF 449 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV---IRTNKALDRESVATHDLKA 657 A D DVG+NG Y L P + + G + K LDRE L Sbjct: 450 PLEAARDKDVGINGLQDYSLSPNSHFSLALETEKRGGKYAELVLQKPLDREEQRELHLVL 509 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A DGG+P +S T V + + D ND+ PVF + ++ENSP G + + A DPDEG Sbjct: 510 TATDGGSPSRSGTAQVRVVVLDANDNMPVFSREVYEVRVAENSPPGQLVVRVSAADPDEG 569 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWN 776 V Y+ + + + +D + LD+E K +ELV+RA L Sbjct: 570 SYGKVRYAFSQTTEGSRQLFDL--NADSGVIRVSGKLDFEE-AKSHELVVRATDGGGLSA 626 Query: 777 DVRVEILVTDVNDNAPVM 794 RV + V DVNDNAP M Sbjct: 627 HCRVHVEVLDVNDNAPEM 644 Score = 131 bits (317), Expect = 2e-28 Identities = 115/400 (28%), Positives = 178/400 (44%), Gaps = 29/400 (7%) Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY-- 547 +V D+G++ + + + +E +Q F ++P +G +T + LDRE + + Sbjct: 127 LVGNVAQDLGLSPSQLAARKARVVSEG---SEQHFRLDPHSGVLTVTETLDRERICPHSE 183 Query: 548 ---LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 LL + V + E+ V DVND+ PVF Q+ +I E A G Sbjct: 184 SCALLFKLFFENPVQLIRG----EVEVRDVNDHSPVFPQKEMVLDISETASPGLRFPLEK 239 Query: 605 ATDADVGLNGRIHYELDPKDREE---GSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 A D DVG+NG +Y L P G + + LDRE L A D Sbjct: 240 AQDEDVGINGLQNYSLSPNSHFSLALGRGKDGDKYAELVLQRPLDREEQRELHLVLTATD 299 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 GG+PP+S T V + + D ND+ PVF + ++ENSP G + + A DPDEG N Sbjct: 300 GGSPPRSGTAQVRVVVLDANDNMPVFSREVYEIRVAENSPPGQLVVRVSAADPDEGSNGK 359 Query: 722 VHYSIKGGDDSNS--FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDV 778 V Y+ + FSL+ G E+ +LD E K +E+V+RA L Sbjct: 360 VRYAFSQTTERTRQLFSLDPGTG----EIRVRGNLDCED-AKNHEMVVRATDGGGLSAHC 414 Query: 779 RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV-TDKLQ-YRILSGNN 836 RV + V DVND++P + ++ + + P F A D DV + LQ Y + ++ Sbjct: 415 RVHVEVRDVNDHSPEFPEKDVVLDVPETASPGTRFPLEAARDKDVGINGLQDYSLSPNSH 474 Query: 837 ANLILLNETTG----SMTLSPQLNTNVPKLATMEVSVTDG 872 +L L E G + L L+ + + ++ TDG Sbjct: 475 FSLALETEKRGGKYAELVLQKPLDREEQRELHLVLTATDG 514 >UniRef50_Q7QJ26 Cluster: ENSANGP00000009575; n=6; Culicidae|Rep: ENSANGP00000009575 - Anopheles gambiae str. PEST Length = 1424 Score = 244 bits (597), Expect = 3e-62 Identities = 359/1345 (26%), Positives = 556/1345 (41%), Gaps = 189/1345 (14%) Query: 18 DHSPVF-EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAX 76 + P F E Y+ ++E GT VL + A DQD N +EY++ + + Sbjct: 13 NRKPTFNECDSYKPMLKEEQPVGTPVLHVNAIDQD--PNQIIEYSLMTTPGERVR----- 65 Query: 77 XXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYT---VLVKATDQASPVSDRLSST 133 FRID +G + T DR++ R + V+ATD P RL Sbjct: 66 -------------FRIDKNTGEITTVHVFDRDEPIREKEIYISVRATDDGRP---RLDDV 109 Query: 134 ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG 193 T+ V I+D NDN P F + Y SV +D+ V N + I ATD D G NS I+Y ++ Sbjct: 110 CTLKVKIVDINDNSPVFDKVRYEESVAKDMKV--NQRVGTISATDMDDGDNSLIKYELLQ 167 Query: 194 GNTQMQF-SIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD---GGSPSRSNTTQLLINIRD 249 F I+ +G V+LVK +D + Y + +RA + G P ++ I + + Sbjct: 168 SLPDSSFFQINENNGLVTLVKQIDRSPGQHYLIHVRAYNLNQQGEPVHHTDVEVKILVME 227 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA------ELTYTMTDKDYTG 303 N +P +++ L +E++ N + ++A+ + EL T++ + Sbjct: 228 SNKRSP-YFSKLPEETIVLNETFKDYSKPIAIFEANSAIPEKPEVIFELIQGRTEETNSK 286 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 + L ++ + LD E A+Y L V+ + D A A Sbjct: 287 HTFLLEQLN-NVATIKLGKALDYEIIAEYTLTVSVKNSDD--LIAEAVLKIQVLDENDII 343 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQNGR 420 F P + E++PPGT V+ + A D D +N + Y ++ F I N Sbjct: 344 PVF-PEMTSGAVLENDPPGTQVMVVKAYDLDGTPANNIVSYRFED-ESQHLFHI--DNIT 399 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSG-------GR--SDTAMVQINITDANNYAPVFEN 471 G I LD +Q Y L V A D+ G+ S T ++ I + D N+ P F + Sbjct: 400 GQIKTLAALDREQTDSYQLKVVAEDNSPSALYRNGKPNSITKLLFIKVMDKNDNKPAFTS 459 Query: 472 APYTAS-VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 + V ED I T V+ V+A D D + + Y++ S NE +A F I+ T Sbjct: 460 QHFVVEGVPEDENINTPVIEVTARDPDA--TSLLHYTIVS--GNEGLA-----FKIDNNT 510 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590 G I+ N LD ET+ Y L V DG D V I V +VNDN P F L I Sbjct: 511 GRISINNRLDYETVREYTLIVQVDDG---IFQDNATVSIKVKNVNDNPPRFTG-LRNVTI 566 Query: 591 MEDALVGTSVSQVGATDADV-GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES 649 E+ + + V A D D+ + H D + + ID SG +R +ALDR+ Sbjct: 567 PEETIPSGCIMTVQAYDPDIENRSDPQHIRFFYVDEYDDAIEIDD-SGCLRLKRALDRDP 625 Query: 650 VATHD-----LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 + A DG +TVI I +EDIND+ P + ++ EN P G Sbjct: 626 PLGSKRWQFIITATDEDGAGKKTPATVI--ISLEDINDNAPRLSNTMPVVWV-ENRPPGL 682 Query: 705 TIGEIRAHDPDEGPNAV-VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY 763 + ++RA D DE N H+SI D + + ++ R EL +V+ D E +K+Y Sbjct: 683 IV-KLRADDVDEPQNGPPFHFSI---DPNARYEIKKRFKVQGEELHALVEFDREE-QKEY 737 Query: 764 EL--VIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD 820 ++ +IR + P+ + +++ D NDN +I NYK P GRV D Sbjct: 738 QIPILIRDSGEEPMSAVSMLHLVIGDDNDNKMRPGKSRIFVYNYKGESPNTEIGRVYVDD 797 Query: 821 ADVTDKLQYRILSGN-----NANLILLNETTGSMTLSPQLNTNVPKLA--TMEVSVTDGV 873 D D + + + LN TG +T+ +L +E S Sbjct: 798 PDDWDLPDKTFIWDDATRHQSVAFFDLNRDTGMITMLQGTRRGDYELNFHVIEHSRHFPR 857 Query: 874 NEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFI---DGLAAIIP----C 926 + + A + ++V+ I EE + S ++R +++TAE+F+S G D L A I Sbjct: 858 HNVTAKVTVTVKEIPEEAVDKSGSIRFHNVTAEEFVSRTPGQLTTPKDRLQASIANTLNV 917 Query: 927 PKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTL 986 +EN+ +F+V + G L+V FSA SP+Y+P L + L Sbjct: 918 SRENVDVFTVLKRDNDNGTFLDVRFSAHG-----------SPYYAPERLNGMMGYQLHQL 966 Query: 987 ARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQC 1046 + VL + C+ E C K + L++ P+ +T Sbjct: 967 EEDVGLSVLMVGIDECIEEG----RNCELSCK-----------NTLYKSNVPIAVYTNT- 1010 Query: 1047 PEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQG-CSIDAAYTTAVCEL 1105 F GVN +A C +C + S + GG L CS + CE+ Sbjct: 1011 -SSFVGVNA---FVQAVC-------VCEAPSPSLTCLNGGFLVNDRCSCPEGFEGPHCEM 1059 Query: 1106 RARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNG--RYNER---HDFLALELV 1160 F S + +P + + ++ + Q GL++Y G YN R DFLALELV Sbjct: 1060 LGIGFYGSGYALYPPTSPCNMTRISVELSPQQEDGLVMYIGPLNYNPRLPVPDFLALELV 1119 Query: 1161 SSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMILDDCDKVLS 1220 G P L + G G I G TVEI +TI MI+D+C LS Sbjct: 1120 K------GLPVLLLDY--GSGTIRIEHRHRFPQGKPFTVEIVLQPQTIEMIVDNCK--LS 1169 Query: 1221 LAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGG----LPNIPSSFQ- 1275 C + P +RFL++ PLQ+GG L ++ S F Sbjct: 1170 -----------TCMSLDAPKGP----------NRFLNVNAPLQLGGAAVNLDSLGSLFNW 1208 Query: 1276 ---VKNKDFVGCISDFYIDHKFIDL 1297 ++K F GC+ + I+ + DL Sbjct: 1209 TYVPQDKGFSGCLRNLTINERTYDL 1233 Score = 183 bits (446), Expect = 5e-44 Identities = 195/732 (26%), Positives = 301/732 (41%), Gaps = 69/732 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ ++D ND+SPVF+ +YE SV + V T+ ATD D G N+ ++Y + D+ Sbjct: 113 KVKIVDINDNSPVFDKVRYEESVAKDMKVNQRVGTISATDMDDGDNSLIKYELLQSLPDS 172 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKA---TDQASPV 126 F+I+ +G + +DR Y + V+A Q PV Sbjct: 173 ------------------SFFQINENNGLVTLVKQIDRSPGQHYLIHVRAYNLNQQGEPV 214 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 + + + +++ N P FS+ T+ ++E P IA +A A + Sbjct: 215 H---HTDVEVKILVMESNKRSPYFSKLPEETIVLNETFKDYSKP-IAIFEANSA-IPEKP 269 Query: 186 AIRYAIIGG-----NTQMQFSIDSLS--GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238 + + +I G N++ F ++ L+ + L K LDYE + Y L + ++ S Sbjct: 270 EVIFELIQGRTEETNSKHTFLLEQLNNVATIKLGKALDYEIIAEYTLTVSVKN--SDDLI 327 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 L I + D ND P F + +V EN P G ++ V+AYD D G A + Sbjct: 328 AEAVLKIQVLDENDIIPVF-PEMTSGAVLENDPPGTQVMVVKAYDLD-GTPANNIVSYRF 385 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG-------GDPPRSATAT 351 +D + ++ ID +G + T LDRE YQL V A D P S T Sbjct: 386 EDESQHL---FHIDNITGQIKTLAALDREQTDSYQLKVVAEDNSPSALYRNGKPNSITKL 442 Query: 352 XXXXXXXXXXXXXXFMPGQYEVE-LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG 410 F + VE + EDE TPV+ +TA D D + LHY I GN Sbjct: 443 LFIKVMDKNDNKPAFTSQHFVVEGVPEDENINTPVIEVTARDPDATSLLHYTIVSGNEGL 502 Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFE 470 F I + GR I++ LD++ R Y L V D G D A V I + + N+ P F Sbjct: 503 AFKIDNNTGR--ISINNRLDYETVREYTLIVQ-VDDGIFQDNATVSIKVKNVNDNPPRFT 559 Query: 471 NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 E P G ++ V A D D+ S I V +D I+ + Sbjct: 560 GLRNVTIPEETIPSG-CIMTVQAYDPDIE-----NRSDPQHIRFFYVDEYDDAIEID-DS 612 Query: 531 GAITTNKLLDRETMSG-----YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585 G + + LDR+ G +++T T DG T V IS+ D+NDN P + Sbjct: 613 GCLRLKRALDRDPPLGSKRWQFIITATDEDGAGKKTPAT--VIISLEDINDNAPRLSNTM 670 Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNG-RIHYELDPKDREEGSFVIDPASGVIRTNKA 644 + E+ G V ++ A D D NG H+ +DP R E + Sbjct: 671 PVVWV-ENRPPGLIV-KLRADDVDEPQNGPPFHFSIDPNARYEIKKRFKVQGEELHALVE 728 Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 DRE + + + D G P S+ ++H+ I D ND+ + Y + T Sbjct: 729 FDREEQKEYQIPILIRDSGEEPMSAVSMLHLVIGDDNDNKMRPGKSRIFVYNYKGESPNT 788 Query: 705 TIGEIRAHDPDE 716 IG + DPD+ Sbjct: 789 EIGRVYVDDPDD 800 Score = 99.5 bits (237), Expect = 1e-18 Identities = 103/354 (29%), Positives = 153/354 (43%), Gaps = 23/354 (6%) Query: 456 QINITDANNYAPVFENAP-YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 + + N P F Y + E+ P+GT VL V+A D D N I YSL + Sbjct: 5 EFSANQVENRKPTFNECDSYKPMLKEEQPVGTPVLHVNAIDQDP--NQIIEYSLMTT-PG 61 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETM---SGYLLTVTARDGGVPSLSDTTDVEISV 571 E V +F I+ TG ITT + DR+ ++V A D G P L D +++ + Sbjct: 62 ERV-----RFRIDKNTGEITTVHVFDRDEPIREKEIYISVRATDDGRPRLDDVCTLKVKI 116 Query: 572 VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631 VD+NDN PVF + Y ++ +D V V + ATD D G N I YEL + F Sbjct: 117 VDINDNSPVFDKVRYEESVAKDMKVNQRVGTISATDMDDGDNSLIKYELLQSLPDSSFFQ 176 Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAI----DGGTPPQSSTVIVHIKIEDINDSPPVF 687 I+ +G++ K +DR S H L V G P + V V I + + N P F Sbjct: 177 INENNGLVTLVKQIDR-SPGQHYLIHVRAYNLNQQGEPVHHTDVEVKILVMESNKRSPYF 235 Query: 688 ES-DCLTFYISEN-SPIGTTIGEIRAHDPDEGPNAVVHYSIKG-GDDSNS-FSLETRQGS 743 T ++E I A+ V+ I+G +++NS + Q + Sbjct: 236 SKLPEETIVLNETFKDYSKPIAIFEANSAIPEKPEVIFELIQGRTEETNSKHTFLLEQLN 295 Query: 744 DKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAPVMKD 796 + A + LDYE +Y L + S L + ++I V D ND PV + Sbjct: 296 NVATIKLGKALDYEI-IAEYTLTVSVKNSDDLIAEAVLKIQVLDENDIIPVFPE 348 >UniRef50_Q8MY75 Cluster: Pf1-cadherin; n=1; Ptychodera flava|Rep: Pf1-cadherin - Ptychodera flava Length = 1959 Score = 244 bits (596), Expect = 4e-62 Identities = 317/1262 (25%), Positives = 514/1262 (40%), Gaps = 156/1262 (12%) Query: 377 EDEPPGTPVVTLTATDADEDNR-----LHYEI--TGGNTRGR--FSITSQNGRGLITVAQ 427 E+ PG V+T+ A D D+ N + Y I N+ G+ F+I S++ + T Sbjct: 579 ENGAPGVTVMTIQAEDLDDPNEGGNALVRYSILRNAQNSVGQAIFAIDSESAV-ITTQVG 637 Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 LD ++ Y + V A D G + T I ++D N+ P F A + E+ P+ ++ Sbjct: 638 NLDREEIPSYDIVVKAVDGGAHTGTVTATIYVSDENDNPPEFPQAKSFVEISENVPVDSS 697 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG--AITTNKLLDRE-TM 544 V V A D DVGIN +YS+ S E + +P +G + K +D E Sbjct: 698 VFKVIAIDRDVGIN---SYSIISGNVGEKF-----RIETDPDSGYAIVKVAKKIDFELNE 749 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 S ++LT+ D + TT+++I V+D ND P F Q Y A ED T++ V Sbjct: 750 SKFVLTIEVDDS---KNTATTELDIRVMDANDEVPSFSQPRYLAEHPEDFAKWTTIGTVA 806 Query: 605 ATDADVGLN-GRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHD------- 654 ATD D I +E+ P+ + F + A+G + K LDRE D Sbjct: 807 ATDRDKSEKFSEIEFEVVRVPEFPDSSFFTVGSANGSVMAIKDLDREPYEDPDQIRENYI 866 Query: 655 LKAVAID-----GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 A D G ++TV + I D+ND+ P F T + EN+P G G + Sbjct: 867 FTVTATDNVRGQSGERRNTATVTFTVSITDVNDNAPEFLPG-YTLLVPENTPAGYEAGVV 925 Query: 710 RAHDPDEGPNA--VVHYSIKGGDDSNSFSLETRQG-SDKAELVTMVDLDYESPRKKYELV 766 D D+ N H I + F + + G D+ +V++ + D E+ Y V Sbjct: 926 EIIDRDDDSNGPPFTHRVIDDDGILSFFDVSSPIGVEDQLRVVSLEEFDREATPFYYIPV 985 Query: 767 IRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVT-- 824 + + + + + + DVNDN P I+ +YK P G V A D D+ Sbjct: 986 VLSDKHGVSATQTLTVTIGDVNDNPPSPATKTILVYSYKGQIPRSAIGEVYAADEDIVKG 1045 Query: 825 DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884 D + Y + + +++ TG + + +EV I ++ + V Sbjct: 1046 DDISYTVTT--PIPQFSVDKDTGQIIIEENTKAGTYDF-KVEVDEKPWPPVICTVI-VEV 1101 Query: 885 RLITEEMLLNSITVRLNDMTAEQFL--SP-LLGFFIDGLAAIIPCPKENIYIFSVQDDTD 941 + I EE + +S +VRL +AE+F+ +P + F D L ++ KENI IFSV Sbjct: 1102 KDIPEEAVFSSGSVRLL-TSAEKFIRGTPSMKDRFHDILVDVLGAKKENIDIFSV----- 1155 Query: 942 VTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNI 1001 +NV + D G SP+Y P + ++ L + + V ++ Sbjct: 1156 -----INVPGEENQCDVRWSAHG--SPYYRPEKMNTQLLLAKDVIESQLGVSFGMVPIDM 1208 Query: 1002 CVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCETILTK 1061 C+ E C ++ + F + + C C G + + Sbjct: 1209 CLDEGICE-SSCTNYFNAITDPTIIDDGADTFVSVTTIQRAECVC-----GAK---LAPR 1259 Query: 1062 ASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCELRARSFPVSSFLTFPGL 1121 C + C +G QC+ G + C D Y CE +R F +SF +P L Sbjct: 1260 GPCA----SNPCLNGGQCIDTPSGYV----CQCDEKYGGPNCEDISRGFQSNSFAWYPPL 1311 Query: 1122 KRRHRIHLKLKFATQTTSGLLLYNG-----RYNERHDFLALELVSSEAGRGGGPGLRFSF 1176 + ++F T++ G++LYNG + DF+A+ELV GG P + Sbjct: 1312 SQCEETKTSIEFLTKSRDGIILYNGPIVPIDLGQPQDFMAIELV------GGKP--KLYM 1363 Query: 1177 SLGGGKSEITVEG-NVGDGSWHTVEIEYFNRTITMILDDCDK-VLSLAGAADFGLKYACA 1234 LG G +T++ + D WHT+EI ++ + +LD C+ V++ + C Sbjct: 1364 DLGSGMLPLTIDSPPLNDEKWHTLEIIRKSKHVEFVLDHCENAVITETERTSVSDESNC- 1422 Query: 1235 NFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLP-----NIPSSFQ-VKNKDFVGCISDF 1288 + T +RFL++ PLQ+GG+ P++F DFVGCI + Sbjct: 1423 ---------KATDTTPGTNRFLNVNTPLQLGGIDMDSTYTYPNTFNFAPGGDFVGCIRNV 1473 Query: 1289 YIDHKFIDLNSYVADNGTLAGCPEKRSRC---SSAPCYNGAECSDLWDTYICDCKEGHTG 1345 D K DL + + + GCP+ C C NG ++ Y C C G G Sbjct: 1474 IQDGKVYDLGTPGREKNSEQGCPQTDLLCYVDGVYVCKNGLCVTESASVYTCVCDPGWGG 1533 Query: 1346 KDCADSTGPPWRFGGDGMLSFNPLLRPIQLPWLNALSI---RTRQRDAFVMSIQ------ 1396 + C D P + F D + ++ + +++ I T++ DA +M +Q Sbjct: 1534 EAC-DEELPSYDFLSDSYVIYDLEASLVSDKYMSDYQIMVGNTQEEDALLMHLQNVDGEE 1592 Query: 1397 -----LKSGLLHYSYN-GE-----TMYLPMATLSDGAWHRIEIKWLGTDISVTVD--YGL 1443 +K G YN G+ ++ + T++DG +H + + G VD G+ Sbjct: 1593 YITMKMKEGNAFIEYNLGDPGMKYSLRVHNYTINDGNYHTVRLLRYGNIFRFEVDGGGGV 1652 Query: 1444 RTVLMPMLANKIQGQYI--GKILIGGLDTTAGLLASDVGFFEGCIQDVR-----IGTAQS 1496 RTV A I ++I K +I G + + + + GC +D R IG Sbjct: 1653 RTV---EKAQGIFKEFIPDPKSVIVGANVSLSEMRVLGDDYSGCAKDARISNSYIGFDGE 1709 Query: 1497 LLNRPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRV--GPQCVSACEL 1554 + V V C C+LS C CV + C+C V G CV E Sbjct: 1710 IDGTIAVPNRVEKDCNI---CLLSPCIAPLVCVPTPSFYYCSCPGDLVFRGGACVK--EG 1764 Query: 1555 GP 1556 GP Sbjct: 1765 GP 1766 Score = 175 bits (426), Expect = 1e-41 Identities = 196/746 (26%), Positives = 307/746 (41%), Gaps = 73/746 (9%) Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 D + I++ DN + +F++ Y SV E+ V+ ++ A + Sbjct: 96 DAWKDSFNIYITKSGDNSEHLKFTQDRYEGSVLENSPA--GTVVYGFESISA-CSECDLV 152 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 Y+++G + +F++++ G V++ + LD E SY L + A + + TT LLI Sbjct: 153 EYSLLGTGEE-KFNLENKDGIVTIQTNEVLDRESRASYNLTLVA--ASASLETETTDLLI 209 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 + DVNDNAP F + +V E P + V A D D G N ++ Y YT Sbjct: 210 TVEDVNDNAPEFDPETCEVTVPEISPADAIVAYVHAVDPDAGKNGKVMY------YTDTN 263 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA-----TXXXXXXXXX 360 D+ ++ P +G V G L + +Y L V A D G P A+ Sbjct: 264 DMTFSVHPDTGGVIIGGPLQAK---EYTLTVFARDRGKPSLEASTPGRVIITVTPVDQSL 320 Query: 361 XXXXXFMPG------------QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT 408 PG + +V L ED P G+ V T+ A D+ ++ + + Sbjct: 321 KFSSILGPGPVILQDDDEELPEIKVSLMEDAPKGSVVTTIKAPSNDKSSQYRF-LMNNPM 379 Query: 409 RGRFSITSQNGRGLITVAQPLDF--KQERRYVLTVSATD---SGGRSDTAMVQINITDAN 463 RF + G ++T +D +E +T D + ++ I ++ + Sbjct: 380 NPRFHVQYYTGDIVLTGRLDIDAHPTEEINVGITKDFNDPLREAPKEQKVIITIIPSETD 439 Query: 464 NYAP---VFENAPYTAS--VFEDAPIGTTVLVVSATDSDVGI---NAQITYSLSSEISNE 515 AP V + AS F+ TV V S V +T + + SN Sbjct: 440 KPAPPNQVVKPRIRRASKPSFDQPSYEGTVEEVDGLASPVPAFVPREILTVRANGDPSNI 499 Query: 516 AV----AHHDQQFVINPQTGAITTNKLLDRETMSGYL--LTVTARDGGVPSLSDTTDVE- 568 A + F I +G I++ K LDRE G + TVTA + + TT VE Sbjct: 500 QYRIQQAEFREDFAIGLTSGIISSRKHLDREDNKGQVREFTVTASNS-----AGTTSVEV 554 Query: 569 -ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD---VGLNGRIHYELDPKD 624 I + DVNDN P F Y + E+ G +V + A D D G N + Y + Sbjct: 555 LIKIKDVNDNAPQFPYPPYIGSFPENGAPGVTVMTIQAEDLDDPNEGGNALVRYSILRNA 614 Query: 625 RE---EGSFVIDPASGVIRTNKA-LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680 + + F ID S VI T LDRE + ++D+ A+DGG + TV I + D Sbjct: 615 QNSVGQAIFAIDSESAVITTQVGNLDREEIPSYDIVVKAVDGGA--HTGTVTATIYVSDE 672 Query: 681 NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR 740 ND+PP F ISEN P+ +++ ++ A D D G N+ YSI G+ F +ET Sbjct: 673 NDNPPEFPQAKSFVEISENVPVDSSVFKVIAIDRDVGINS---YSIISGNVGEKFRIETD 729 Query: 741 QGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQII 800 S A + +D+E K+ L I ++I V D ND P + + Sbjct: 730 PDSGYAIVKVAKKIDFELNESKFVLTIEVDDSKNTATTELDIRVMDANDEVPSFSQPRYL 789 Query: 801 FNNYKDCFPVGPFGRVPAYDADVTDK 826 + +D G V A D D ++K Sbjct: 790 AEHPEDFAKWTTIGTVAATDRDKSEK 815 Score = 170 bits (413), Expect = 5e-40 Identities = 175/612 (28%), Positives = 262/612 (42%), Gaps = 50/612 (8%) Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN---SAIRYAIIGGNTQMQFSIDS 204 P F + +Y +V+E + +PV A + V AN S I+Y I + F+I Sbjct: 458 PSFDQPSYEGTVEE-VDGLASPVPAFVPREILTVRANGDPSNIQYRIQQAEFREDFAIGL 516 Query: 205 LSGDVSLVKTLDYE----QVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260 SG +S K LD E QVR + V + G+ S ++LI I+DVNDNAP+F Sbjct: 517 TSGIISSRKHLDREDNKGQVREF-TVTASNSAGTTS----VEVLIKIKDVNDNAPQFPYP 571 Query: 261 LFQESVSENVPIGYSIVRVQAYDAD---EGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317 + S EN G +++ +QA D D EG NA + Y++ ID S Sbjct: 572 PYIGSFPENGAPGVTVMTIQAEDLDDPNEGGNALVRYSILRNAQNSVGQAIFAIDSESAV 631 Query: 318 VYTS-GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376 + T G LDRE Y ++V A DGG + T T F + VE++ Sbjct: 632 ITTQVGNLDREEIPSYDIVVKAVDGG--AHTGTVTATIYVSDENDNPPEFPQAKSFVEIS 689 Query: 377 EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITS--QNGRGLITVAQPLDFK-Q 433 E+ P + V + A D D Y I GN +F I + +G ++ VA+ +DF+ Sbjct: 690 ENVPVDSSVFKVIAIDRDVGIN-SYSIISGNVGEKFRIETDPDSGYAIVKVAKKIDFELN 748 Query: 434 ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 E ++VLT+ DS + T + I + DAN+ P F Y A ED TT+ V+A Sbjct: 749 ESKFVLTIEVDDSKNTATTEL-DIRVMDANDEVPSFSQPRYLAEHPEDFAKWTTIGTVAA 807 Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE-------TMSG 546 TD D ++ + E+ F + G++ K LDRE Sbjct: 808 TDRD---KSEKFSEIEFEVVRVPEFPDSSFFTVGSANGSVMAIKDLDREPYEDPDQIREN 864 Query: 547 YLLTVTARD-----GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 Y+ TVTA D G + T +S+ DVNDN P F YT + E+ G Sbjct: 865 YIFTVTATDNVRGQSGERRNTATVTFTVSITDVNDNAPEFLPG-YTLLVPENTPAGYEAG 923 Query: 602 QVGATDADVGLNGR--IHYELDPKDREEGSFVIDPASGV-----IRTNKALDRESVATHD 654 V D D NG H +D D F + GV + + + DRE+ + Sbjct: 924 VVEIIDRDDDSNGPPFTHRVID-DDGILSFFDVSSPIGVEDQLRVVSLEEFDREATPFYY 982 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 + V D S+T + + I D+ND+PP + + Y + + IGE+ A D Sbjct: 983 IPVVLSD--KHGVSATQTLTVTIGDVNDNPPSPATKTILVYSYKGQIPRSAIGEVYAADE 1040 Query: 715 DEGPNAVVHYSI 726 D + Y++ Sbjct: 1041 DIVKGDDISYTV 1052 Score = 161 bits (392), Expect = 2e-37 Identities = 204/768 (26%), Positives = 321/768 (41%), Gaps = 88/768 (11%) Query: 87 QDVFRIDGRSG--ALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDN 144 ++ F ++ + G + T LDRE A Y + + A + + T + + + D N Sbjct: 161 EEKFNLENKDGIVTIQTNEVLDRESRASYNLTLVAASASLE-----TETTDLLITVEDVN 215 Query: 145 DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS 204 DN P+F +T V+V E IS D ++A + A D D G N + Y M FS+ Sbjct: 216 DNAPEFDPETCEVTVPE-ISPAD-AIVAYVHAVDPDAGKNGKVMYYT--DTNDMTFSVHP 271 Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT--QLLINIRDVNDNAPRFYTSL- 261 +G V + L Q + Y L + A+D G PS +T +++I + V D + +F + L Sbjct: 272 DTGGVIIGGPL---QAKEYTLTVFARDRGKPSLEASTPGRVIITVTPV-DQSLKFSSILG 327 Query: 262 ---------------FQESVSENVPIGYSIVRVQAYDADEG------VNAELTYTMTDKD 300 + S+ E+ P G + ++A D+ +N + + Sbjct: 328 PGPVILQDDDEELPEIKVSLMEDAPKGSVVTTIKAPSNDKSSQYRFLMNNPMNPRFHVQY 387 Query: 301 YTGNVDLP--ITIDPRS------GWVYTSGQLDRETQAKYQLLVT----ATDGGDPPRSA 348 YTG++ L + ID G RE + ++++T TD PP Sbjct: 388 YTGDIVLTGRLDIDAHPTEEINVGITKDFNDPLREAPKEQKVIITIIPSETDKPAPPNQV 447 Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVE-LAEDEPPGTPVVTLTATDADEDNRLHYEITGGN 407 + EV+ LA P P LT + + + Y I Sbjct: 448 VKPRIRRASKPSFDQPSYEGTVEEVDGLASPVPAFVPREILTVRANGDPSNIQYRIQQAE 507 Query: 408 TRGRFSITSQNGRGLITVAQPLDFKQERRYV--LTVSATDSGGRSDTAMVQINITDANNY 465 R F+I + G+I+ + LD + + V TV+A++S G + + V I I D N+ Sbjct: 508 FREDFAIGLTS--GIISSRKHLDREDNKGQVREFTVTASNSAG-TTSVEVLIKIKDVNDN 564 Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSD---VGINAQITYSLSSEISNEAVAHHDQ 522 AP F PY S E+ G TV+ + A D D G NA + YS+ N Sbjct: 565 APQFPYPPYIGSFPENGAPGVTVMTIQAEDLDDPNEGGNALVRYSILRNAQNSV---GQA 621 Query: 523 QFVINPQTGAITTN-KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581 F I+ ++ ITT LDRE + Y + V A DGG + + T I V D NDN P F Sbjct: 622 IFAIDSESAVITTQVGNLDREEIPSYDIVVKAVDGG--AHTGTVTATIYVSDENDNPPEF 679 Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG--VI 639 Q I E+ V +SV +V A D DVG+N + + E+ DP SG ++ Sbjct: 680 PQAKSFVEISENVPVDSSVFKVIAIDRDVGINS--YSIISGNVGEKFRIETDPDSGYAIV 737 Query: 640 RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699 + K +D E + + + +D ++T + I++ D ND P F E+ Sbjct: 738 KVAKKIDFELNESKFVLTIEVDDS--KNTATTELDIRVMDANDEVPSFSQPRYLAEHPED 795 Query: 700 SPIGTTIGEIRAHDPDEGPN-AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD--- 755 TTIG + A D D+ + + + + + S T GS ++ + DLD Sbjct: 796 FAKWTTIGTVAATDRDKSEKFSEIEFEVVRVPEFPDSSFFT-VGSANGSVMAIKDLDREP 854 Query: 756 YESP---RKKYELV------IRAASPPLWNDVRV--EILVTDVNDNAP 792 YE P R+ Y +R S N V + +TDVNDNAP Sbjct: 855 YEDPDQIRENYIFTVTATDNVRGQSGERRNTATVTFTVSITDVNDNAP 902 Score = 151 bits (366), Expect = 3e-34 Identities = 186/660 (28%), Positives = 284/660 (43%), Gaps = 70/660 (10%) Query: 90 FRIDGRSGALLTRASLDRE----KVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145 F I SG + +R LDRE +V +TV A++ A S + + I D ND Sbjct: 512 FAIGLTSGIISSRKHLDREDNKGQVREFTVT--ASNSAGTTS------VEVLIKIKDVND 563 Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD---VGANSAIRYAIIGG--NT--QM 198 N PQF Y S E+ + + I+A D D G N+ +RY+I+ N+ Q Sbjct: 564 NAPQFPYPPYIGSFPENGA--PGVTVMTIQAEDLDDPNEGGNALVRYSILRNAQNSVGQA 621 Query: 199 QFSIDSLSGDVSL-VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF 257 F+IDS S ++ V LD E++ SY +V++A DGG+ + T I + D NDN P F Sbjct: 622 IFAIDSESAVITTQVGNLDREEIPSYDIVVKAVDGGA--HTGTVTATIYVSDENDNPPEF 679 Query: 258 YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV--DLPITIDPRS 315 + +SENVP+ S+ +V A D D G+N +Y++ +GNV I DP S Sbjct: 680 PQAKSFVEISENVPVDSSVFKVIAIDRDVGIN---SYSI----ISGNVGEKFRIETDPDS 732 Query: 316 GW--VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373 G+ V + ++D E +L D D +AT F +Y Sbjct: 733 GYAIVKVAKKIDFELNESKFVLTIEVD--DSKNTATTELDIRVMDANDEVPSFSQPRYLA 790 Query: 374 ELAEDEPPGTPVVTLTATDADEDNR---LHYEIT---GGNTRGRFSITSQNGRGLITV-- 425 E ED T + T+ ATD D+ + + +E+ F++ S NG + Sbjct: 791 EHPEDFAKWTTIGTVAATDRDKSEKFSEIEFEVVRVPEFPDSSFFTVGSANGSVMAIKDL 850 Query: 426 -AQPLDFKQERR--YVLTVSATD-----SGGRSDTAMV--QINITDANNYAPVFENAPYT 475 +P + + R Y+ TV+ATD SG R +TA V ++ITD N+ AP F YT Sbjct: 851 DREPYEDPDQIRENYIFTVTATDNVRGQSGERRNTATVTFTVSITDVNDNAPEFLPG-YT 909 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINA-QITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 V E+ P G VV D D N T+ + + + + Q ++ Sbjct: 910 LLVPENTPAGYEAGVVEIIDRDDDSNGPPFTHRVIDDDGILSFFDVSSPIGVEDQLRVVS 969 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 + DRE Y + V D +S T + +++ DVNDN P + + Sbjct: 970 LEE-FDREATPFYYIPVVLSD--KHGVSATQTLTVTIGDVNDNPPSPATKTILVYSYKGQ 1026 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654 + +++ +V A D D+ I Y + + F +D +G I + T+D Sbjct: 1027 IPRSAIGEVYAADEDIVKGDDISYTVTTPIPQ---FSVDKDTGQIIIE---ENTKAGTYD 1080 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI-GTTIGEIRAHD 713 K + PP TVIV +K DI + VF S + S I GT + R HD Sbjct: 1081 FKVEVDEKPWPPVICTVIVEVK--DIPEE-AVFSSGSVRLLTSAEKFIRGTPSMKDRFHD 1137 Score = 139 bits (337), Expect = 9e-31 Identities = 151/553 (27%), Positives = 235/553 (42%), Gaps = 59/553 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVTA 67 I + D ND++P F Y S E + G TV+T++A D D G NA V Y+I Sbjct: 556 IKIKDVNDNAPQFPYPPYIGSFPENGAPGVTVMTIQAEDLDDPNEGGNALVRYSI----- 610 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR-ASLDREKVARYTVLVKATDQASPV 126 N +++ Q +F ID S + T+ +LDRE++ Y ++VKA D + Sbjct: 611 -LRNAQNSVG---------QAIFAIDSESAVITTQVGNLDREEIPSYDIVVKAVDGGAHT 660 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 + TATI+V+ D+NDN P+F + V + E++ V + + K+ A D DVG NS Sbjct: 661 G---TVTATIYVS--DENDNPPEFPQAKSFVEISENVPVDSS--VFKVIAIDRDVGINS- 712 Query: 187 IRYAIIGGNTQMQFSI----DSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGGSPSRSNTT 241 Y+II GN +F I DS V + K +D+E S + L I D + TT Sbjct: 713 --YSIISGNVGEKFRIETDPDSGYAIVKVAKKIDFELNESKFVLTIEVDDS---KNTATT 767 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN-AELTYTMTDKD 300 +L I + D ND P F + E+ +I V A D D+ +E+ + + Sbjct: 768 ELDIRVMDANDEVPSFSQPRYLAEHPEDFAKWTTIGTVAATDRDKSEKFSEIEFEVVRVP 827 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRE-------TQAKYQLLVTATD-----GGDPPRSA 348 + T+ +G V LDRE + Y VTATD G+ +A Sbjct: 828 EFPDSSF-FTVGSANGSVMAIKDLDREPYEDPDQIRENYIFTVTATDNVRGQSGERRNTA 886 Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR----LHYEIT 404 T T F+PG Y + + E+ P G + D D+D+ H I Sbjct: 887 TVTFTVSITDVNDNAPEFLPG-YTLLVPENTPAGYEAGVVEIIDRDDDSNGPPFTHRVID 945 Query: 405 GGNTRGRFSITSQNG-RGLITVAQPLDFKQERR--YVLTVSATDSGGRSDTAMVQINITD 461 F ++S G + V +F +E Y + V +D G S T + + I D Sbjct: 946 DDGILSFFDVSSPIGVEDQLRVVSLEEFDREATPFYYIPVVLSDKHGVSATQTLTVTIGD 1005 Query: 462 ANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521 N+ P ++ + + V A D D+ I+Y++++ I +V Sbjct: 1006 VNDNPPSPATKTILVYSYKGQIPRSAIGEVYAADEDIVKGDDISYTVTTPIPQFSVDKDT 1065 Query: 522 QQFVINPQTGAIT 534 Q +I T A T Sbjct: 1066 GQIIIEENTKAGT 1078 Score = 92.3 bits (219), Expect = 2e-16 Identities = 169/636 (26%), Positives = 246/636 (38%), Gaps = 79/636 (12%) Query: 251 NDNAPRFYTSLFQESVSENVPIG---YSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 N +F ++ SV EN P G Y + A + V L T +K N D Sbjct: 112 NSEHLKFTQDRYEGSVLENSPAGTVVYGFESISACSECDLVEYSLLGTGEEKFNLENKDG 171 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 +TI T+ LDRE++A Y L + A + T F Sbjct: 172 IVTIQ-------TNEVLDRESRASYNLTLVAASAS--LETETTDLLITVEDVNDNAPEFD 222 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNR---LHYEITGGNTRGRFSITSQNGRGLIT 424 P EV + E P V + A D D ++Y T T FS+ G G+I Sbjct: 223 PETCEVTVPEISPADAIVAYVHAVDPDAGKNGKVMYYTDTNDMT---FSVHPDTG-GVI- 277 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAM----VQINITDANNY---------APVF-- 469 + PL Q + Y LTV A D G S A V I +T + PV Sbjct: 278 IGGPL---QAKEYTLTVFARDRGKPSLEASTPGRVIITVTPVDQSLKFSSILGPGPVILQ 334 Query: 470 ---ENAP-YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA-VAHHDQQF 524 E P S+ EDAP G+ V + A +D ++Q + +++ ++ V ++ Sbjct: 335 DDDEELPEIKVSLMEDAPKGSVVTTIKAPSNDK--SSQYRFLMNNPMNPRFHVQYYTGDI 392 Query: 525 VINPQ-------TGAITTNKLLD-----RETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572 V+ + T I D RE + +T +PS +D VV Sbjct: 393 VLTGRLDIDAHPTEEINVGITKDFNDPLREAPKEQKVIITI----IPSETDKPAPPNQVV 448 Query: 573 DVN---DNEPVFKQQLYTANIME-DALVGTSVSQVGATDADVGLNG---RIHYELDPKDR 625 ++P F Q Y + E D L + V V NG I Y + + Sbjct: 449 KPRIRRASKPSFDQPSYEGTVEEVDGLASPVPAFVPREILTVRANGDPSNIQYRIQQAEF 508 Query: 626 EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685 E F I SG+I + K LDRE ++ + +++V V IKI+D+ND+ P Sbjct: 509 RE-DFAIGLTSGIISSRKHLDRED-NKGQVREFTVTASNSAGTTSVEVLIKIKDVNDNAP 566 Query: 686 VFESDCLTFYISENSPIGTTIGEIRAH---DPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 F EN G T+ I+A DP+EG NA+V YSI ++ Sbjct: 567 QFPYPPYIGSFPENGAPGVTVMTIQAEDLDDPNEGGNALVRYSILRNAQNSVGQAIFAID 626 Query: 743 SDKAELVTMV-DLDYESPRKKYELVIRAASPPL-WNDVRVEILVTDVNDNAPVMKDFQII 800 S+ A + T V +LD E Y++V++A V I V+D NDN P + Sbjct: 627 SESAVITTQVGNLDREE-IPSYDIVVKAVDGGAHTGTVTATIYVSDENDNPPEFPQAK-S 684 Query: 801 FNNYKDCFPV-GPFGRVPAYDADVTDKLQYRILSGN 835 F + PV +V A D DV Y I+SGN Sbjct: 685 FVEISENVPVDSSVFKVIAIDRDVGIN-SYSIISGN 719 Score = 76.2 bits (179), Expect = 1e-11 Identities = 67/248 (27%), Positives = 110/248 (44%), Gaps = 20/248 (8%) Query: 421 GLITVAQPL-DFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479 G+I + L D+ V+ D D+ + I + N+ F Y SV Sbjct: 69 GIIRSMEELTDYANRMFSVVVEQFLDDDAWKDSFNIYITKSGDNSEHLKFTQDRYEGSVL 128 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT--TNK 537 E++P GT V + + + + YSL + +++F + + G +T TN+ Sbjct: 129 ENSPAGTVVYGFESISACSECDL-VEYSL--------LGTGEEKFNLENKDGIVTIQTNE 179 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 +LDRE+ + Y LT+ A + + +TTD+ I+V DVNDN P F + + E + Sbjct: 180 VLDRESRASYNLTLVAASASLET--ETTDLLITVEDVNDNAPEFDPETCEVTVPEISPAD 237 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 V+ V A D D G NG++ Y D D +F + P +G + L + + L Sbjct: 238 AIVAYVHAVDPDAGKNGKVMYYTDTNDM---TFSVHPDTGGVIIGGPLQAKE---YTLTV 291 Query: 658 VAIDGGTP 665 A D G P Sbjct: 292 FARDRGKP 299 Score = 46.0 bits (104), Expect = 0.015 Identities = 50/209 (23%), Positives = 85/209 (40%), Gaps = 17/209 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD-T 69 I V D ND++P F+ + E +V E + + V + A D D GKN +V Y + + Sbjct: 209 ITVEDVNDNAPEFDPETCEVTVPEISPADAIVAYVHAVDPDAGKNGKVMYYTDTNDMTFS 268 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 ++P+ + + R + SL+ R + V DQ+ S Sbjct: 269 VHPDTGGVIIGGPLQAKEYTLTVFARDRG---KPSLEASTPGRVIITVTPVDQSLKFSSI 325 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L I + DD++ P+ VS+ ED V+ IKA D +S R+ Sbjct: 326 LGPGPVI---LQDDDEELPEIK-----VSLMED--APKGSVVTTIKAPSND--KSSQYRF 373 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYE 218 ++ +F + +GD+ L LD + Sbjct: 374 -LMNNPMNPRFHVQYYTGDIVLTGRLDID 401 >UniRef50_UPI00015A41E3 Cluster: UPI00015A41E3 related cluster; n=2; Danio rerio|Rep: UPI00015A41E3 UniRef100 entry - Danio rerio Length = 1114 Score = 243 bits (595), Expect = 5e-62 Identities = 230/825 (27%), Positives = 364/825 (44%), Gaps = 75/825 (9%) Query: 59 EYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVK 118 EY ++V D P+D F ++ +G + + LDRE + + Sbjct: 44 EYAFKIVATD---PDDDPLTYKIAGTNA-GFFTVEEHTGIVTIKILLDRETTQHFKCTLV 99 Query: 119 ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178 +T A + ++ T I++N+ D NDN P F+ Y V E+ +V V+ ATD Sbjct: 100 STYNAPTLFIQVRKT--IYINVEDANDNIPIFNGLPYNKEVLENTTV--GFVLFTASATD 155 Query: 179 ADVGANSAIRYAI--IGGNTQMQFSIDSLSGDVSLVKTLDY-EQVRSYRLVIRAQDGGSP 235 +D G + Y I + + + FSI + +G V+LV L++ E+ Y++ I A DGG Sbjct: 156 SDFGQAGIVSYKIDEVVPDDKDMFSIVAATGVVTLVGNLNFTEKSPFYQIRINASDGGGE 215 Query: 236 S------RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN 289 +S++ I ++DV D P+F +V EN +G ++ V+A D D GVN Sbjct: 216 LYGEEVVQSSSAIAFITVKDVPDIDPQFLNLPNNAAVEENTGVGTTVFTVRARDPDTGVN 275 Query: 290 AELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET----QAKYQLLVTATDGGDPP 345 ++T+++ D T DL ID +G V + ++DRE A L + A++ Sbjct: 276 DKITFSI---DKTNASDL-FRIDTNTGIVSVNAEIDREELLNISATVVLKIKASETMPNV 331 Query: 346 RSATATXXXXXXXXXXXXXXFMPGQYEVE-------------LAEDEPPGTPVVTLTAT- 391 A+ P YE E + E G V L Sbjct: 332 NGVIASTIGELQISIKDENDNSPEFYECEGEACMKKDNFEGNVNEHSSTGLAVANLNIKV 391 Query: 392 ---DADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA------QPLDFKQERRYVLTVS 442 D E++ + + G + + F ++ +G G TV Q +D++ ++ + + Sbjct: 392 KDLDGGENSTFNLHLDGPD-KDAFRVSPTSGMGESTVQVLVKDPQAVDYEIKQIMNVQII 450 Query: 443 ATDSGGR-SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501 A D+ + TA V I++ D N+ P FE Y VFE GT V + ATD+D Sbjct: 451 AVDANADFTSTATVTIHLNDTNDNFPTFEKELYKEKVFEHCENGTIVATIIATDADAFDE 510 Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL 561 +ITY L E H++ I +T LD E Y LT+ A D G + Sbjct: 511 GKITYRLMPESIRSLFGVHEKTGTIY-----VTNGDTLDWEVTKSYTLTLQAFDSG--NN 563 Query: 562 SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG--LNGRIHYE 619 + TT VEIS++D+NDN P + +Y A + E+ Q+ ATD D LN + Y Sbjct: 564 TGTTVVEISILDINDNAPEMNRDIYEAFVQENE---DFKIQIQATDRDEPKTLNSEVQYR 620 Query: 620 LDPKDREEGSFVIDPASGVIRTNKALDRESV-----ATHDLKAVAIDGGTPPQSSTVIVH 674 + + +F I SG++ LDRE++ L +A D GTP +SS+ V+ Sbjct: 621 ISEESTFSSNFTIGLESGLLTNKGDLDREAIDISQNGVIQLIVIASDLGTPSRSSSAKVN 680 Query: 675 IKIEDINDSPPVF-ESDCLTFYISENSPIGTTIGEIRAHDPDEGP-NAVVHYSIKGGDDS 732 I + D ND+ P + +S F + E S G +G + AHD D+ N + +SI G Sbjct: 681 ISVGDANDNAPRYLDSSPYEFRVKE-SVKGIYVGPVHAHDADQTDFNNRIFFSITDGSFG 739 Query: 733 NSFSLETRQGSDKAELVTM---VDLDYESPRKKYELVIRAASPPLWNDV-RVEILVTDVN 788 + +T+ V+LDYES RK+Y L ++A+ +DV V I+V DVN Sbjct: 740 SFIIYSEAFSKGYRGNITVDPSVELDYESNRKEYTLKVQASDLGQKSDVAEVHIIVEDVN 799 Query: 789 DNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILS 833 D P I+ + PV P + D D L Y ++S Sbjct: 800 DTPPEFPSGMILKVDENTTLPV-PVDTIKGKDVDTNHSLIYELVS 843 Score = 206 bits (503), Expect = 7e-51 Identities = 206/755 (27%), Positives = 330/755 (43%), Gaps = 89/755 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 INV D ND+ P+F Y V E + G + T ATD D G+ V Y I+ V Sbjct: 117 INVEDANDNIPIFNGLPYNKEVLENTTVGFVLFTASATDSDFGQAGIVSYKIDEVV---- 172 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLD-REKVARYTVLVKATDQASPVSDR 129 P+D +D+F I +G + +L+ EK Y + + A+D + Sbjct: 173 -PDD------------KDMFSIVAATGVVTLVGNLNFTEKSPFYQIRINASDGGGELYGE 219 Query: 130 ---LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 SS+A + + D D PQF +V+E+ V + ++A D D G N Sbjct: 220 EVVQSSSAIAFITVKDVPDIDPQFLNLPNNAAVEENTGV--GTTVFTVRARDPDTGVNDK 277 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT----- 241 I ++I N F ID+ +G VS+ +D E++ + + + S + N Sbjct: 278 ITFSIDKTNASDLFRIDTNTGIVSVNAEIDREELLNISATVVLKIKASETMPNVNGVIAS 337 Query: 242 ---QLLINIRDVNDNAPRFYT---------SLFQESVSENVPIGYSI--VRVQAYDADEG 287 +L I+I+D NDN+P FY F+ +V+E+ G ++ + ++ D D G Sbjct: 338 TIGELQISIKDENDNSPEFYECEGEACMKKDNFEGNVNEHSSTGLAVANLNIKVKDLDGG 397 Query: 288 VNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL--------DRETQAKYQLLVTAT 339 N+ + D + P SG ++ Q+ D E + + + A Sbjct: 398 ENSTFNLHLDGPDKDA-----FRVSPTSGMGESTVQVLVKDPQAVDYEIKQIMNVQIIAV 452 Query: 340 DGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDN 397 D + ++TAT F Y+ ++ E GT V T+ ATDAD ++ Sbjct: 453 DA-NADFTSTATVTIHLNDTNDNFPTFEKELYKEKVFEHCENGTIVATIIATDADAFDEG 511 Query: 398 RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQI 457 ++ Y + + R F + + G +T LD++ + Y LT+ A DSG + T +V+I Sbjct: 512 KITYRLMPESIRSLFGVHEKTGTIYVTNGDTLDWEVTKSYTLTLQAFDSGNNTGTTVVEI 571 Query: 458 NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD--VGINAQITYSLSSEISNE 515 +I D N+ AP Y A V E+ + + ATD D +N+++ Y +S E Sbjct: 572 SILDINDNAPEMNRDIYEAFVQENEDF---KIQIQATDRDEPKTLNSEVQYRISEE---- 624 Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRE----TMSGYL-LTVTARDGGVPSLSDTTDVEIS 570 + F I ++G +T LDRE + +G + L V A D G PS S + V IS Sbjct: 625 --STFSSNFTIGLESGLLTNKGDLDREAIDISQNGVIQLIVIASDLGTPSRSSSAKVNIS 682 Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGS 629 V D NDN P + +++++ G V V A DAD N RI + + D GS Sbjct: 683 VGDANDNAPRYLDSSPYEFRVKESVKGIYVGPVHAHDADQTDFNNRIFFSI--TDGSFGS 740 Query: 630 FVI--DPASGVIRTNKALD-------RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680 F+I + S R N +D + + LK A D G +S VHI +ED+ Sbjct: 741 FIIYSEAFSKGYRGNITVDPSVELDYESNRKEYTLKVQASDLG--QKSDVAEVHIIVEDV 798 Query: 681 NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 ND+PP F S + + EN+ + + I+ D D Sbjct: 799 NDTPPEFPSG-MILKVDENTTLPVPVDTIKGKDVD 832 Score = 181 bits (441), Expect = 2e-43 Identities = 187/648 (28%), Positives = 292/648 (45%), Gaps = 75/648 (11%) Query: 10 QINVLDCNDHSPVF---------EMQQYEASVREGASSGTTV--LTLKATDQDIGKNAEV 58 QI++ D ND+SP F + +E +V E +S+G V L +K D D G+N+ Sbjct: 343 QISIKDENDNSPEFYECEGEACMKKDNFEGNVNEHSSTGLAVANLNIKVKDLDGGENSTF 402 Query: 59 EYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVK 118 ++ D VQ + + ++D E V + Sbjct: 403 NLHLDGPDKDAFR---VSPTSGMGESTVQVLVK---------DPQAVDYEIKQIMNVQII 450 Query: 119 ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178 A D + +STAT+ +++ D NDN+P F ++ Y V E + ++A I ATD Sbjct: 451 AVDANAD----FTSTATVTIHLNDTNDNFPTFEKELYKEKVFEHCE--NGTIVATIIATD 504 Query: 179 ADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVK--TLDYEQVRSYRLVIRAQDGGSPS 236 AD I Y ++ + + F + +G + + TLD+E +SY L ++A D G+ Sbjct: 505 ADAFDEGKITYRLMPESIRSLFGVHEKTGTIYVTNGDTLDWEVTKSYTLTLQAFDSGN-- 562 Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG--VNAELTY 294 + TT + I+I D+NDNAP +++ V EN +++QA D DE +N+E+ Y Sbjct: 563 NTGTTVVEISILDINDNAPEMNRDIYEAFVQENEDFK---IQIQATDRDEPKTLNSEVQY 619 Query: 295 TMTDKD-YTGNVDLPITIDPRSGWVYTSGQLDRET-----QAKYQLLVTATDGGDPPRSA 348 ++++ ++ N TI SG + G LDRE QL+V A+D G P RS+ Sbjct: 620 RISEESTFSSN----FTIGLESGLLTNKGDLDREAIDISQNGVIQLIVIASDLGTPSRSS 675 Query: 349 TATXXXXXXXXXXXXXXFMPGQ-YEVELAEDEPPGTPVVTLTATDADE---DNRLHYEIT 404 +A ++ YE + E G V + A DAD+ +NR+ + IT Sbjct: 676 SAKVNISVGDANDNAPRYLDSSPYEFRVKESVK-GIYVGPVHAHDADQTDFNNRIFFSIT 734 Query: 405 GGNTRGRFSITSQ----NGRGLITV--AQPLDFKQERR-YVLTVSATDSGGRSDTAMVQI 457 G+ G F I S+ RG ITV + LD++ R+ Y L V A+D G +SD A V I Sbjct: 735 DGSF-GSFIIYSEAFSKGYRGNITVDPSVELDYESNRKEYTLKVQASDLGQKSDVAEVHI 793 Query: 458 NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS--NE 515 + D N+ P F + V E+ + V + D D N + Y L S N Sbjct: 794 IVEDVNDTPPEFPSG-MILKVDENTTLPVPVDTIKGKDVDT--NHSLIYELVSTKCQCNG 850 Query: 516 AVAHHDQQFVINPQTGAITTNK--LLDRETMSGYLLTVTARD----GGVPSLSDTTDVEI 569 + +++ I G I N ++D E LT D G S + V I Sbjct: 851 TIGPCPEEWFIVESNGDIIANTEYVIDYEKCDVVFLTARVVDIYTEVGSNSSEGSGVVTI 910 Query: 570 SVVDVNDNEP--VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615 ++VD+NDN P VF Q Y ++E GTSV++ ATD D N + Sbjct: 911 NIVDINDNAPEFVFLQDFYVV-VIEKVDTGTSVARAYATDRDTADNNK 957 Score = 155 bits (376), Expect = 2e-35 Identities = 193/770 (25%), Positives = 323/770 (41%), Gaps = 71/770 (9%) Query: 154 TYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVK 213 T V + ED+ + + KI ATD D + + Y I G N F+++ +G V++ Sbjct: 31 TSVVILREDLRIGEYAF--KIVATDPD---DDPLTYKIAGTNAGF-FTVEEHTGIVTIKI 84 Query: 214 TLDYEQVRSYRL-VIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI 272 LD E + ++ ++ + + + IN+ D NDN P F + + V EN + Sbjct: 85 LLDRETTQHFKCTLVSTYNAPTLFIQVRKTIYINVEDANDNIPIFNGLPYNKEVLENTTV 144 Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD-RETQAK 331 G+ + A D+D G ++Y + D+ + D+ +I +G V G L+ E Sbjct: 145 GFVLFTASATDSDFGQAGIVSYKI-DEVVPDDKDM-FSIVAATGVVTLVGNLNFTEKSPF 202 Query: 332 YQLLVTATDGG------DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 YQ+ + A+DGG + +S++A F+ + E+ GT V Sbjct: 203 YQIRINASDGGGELYGEEVVQSSSAIAFITVKDVPDIDPQFLNLPNNAAVEENTGVGTTV 262 Query: 386 VTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ----ERRYVL 439 T+ A D D ++++ + I N F I + G+++V +D ++ VL Sbjct: 263 FTVRARDPDTGVNDKITFSIDKTNASDLFRIDTNT--GIVSVNAEIDREELLNISATVVL 320 Query: 440 TVSATDS----GG--RSDTAMVQINITDANNYAPVF---------ENAPYTASVFEDAPI 484 + A+++ G S +QI+I D N+ +P F + + +V E + Sbjct: 321 KIKASETMPNVNGVIASTIGELQISIKDENDNSPEFYECEGEACMKKDNFEGNVNEHSST 380 Query: 485 GTTV--LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 G V L + D D G N+ L + + + + +D E Sbjct: 381 GLAVANLNIKVKDLDGGENSTFNLHLDGPDKDAFRVSPTSGMGESTVQVLVKDPQAVDYE 440 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 + + A D + T V I + D NDN P F+++LY + E GT V+ Sbjct: 441 IKQIMNVQIIAVDANA-DFTSTATVTIHLNDTNDNFPTFEKELYKEKVFEHCENGTIVAT 499 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN-KALDRESVATHDLKAVAID 661 + ATDAD G+I Y L P+ V + + TN LD E ++ L A D Sbjct: 500 IIATDADAFDEGKITYRLMPESIRSLFGVHEKTGTIYVTNGDTLDWEVTKSYTLTLQAFD 559 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP--N 719 G + T +V I I DIND+ P D ++ EN +I+A D DE N Sbjct: 560 SGN--NTGTTVVEISILDINDNAPEMNRDIYEAFVQENEDFKI---QIQATDRDEPKTLN 614 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE----SPRKKYELVIRAA---SP 772 + V Y I + ++FS G + L DLD E S +L++ A+ +P Sbjct: 615 SEVQYRI---SEESTFSSNFTIGLESGLLTNKGDLDREAIDISQNGVIQLIVIASDLGTP 671 Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD---KLQY 829 + +V I V D NDNAP D K+ G V A+DAD TD ++ + Sbjct: 672 SRSSSAKVNISVGDANDNAPRYLDSSPYEFRVKESVKGIYVGPVHAHDADQTDFNNRIFF 731 Query: 830 RILSGNNANLILLNET-----TGSMTLSPQLNTNVP---KLATMEVSVTD 871 I G+ + I+ +E G++T+ P + + K T++V +D Sbjct: 732 SITDGSFGSFIIYSEAFSKGYRGNITVDPSVELDYESNRKEYTLKVQASD 781 Score = 155 bits (375), Expect = 2e-35 Identities = 207/765 (27%), Positives = 321/765 (41%), Gaps = 96/765 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D D P F A+V E GTTV T++A D D G N ++ ++I+ A Sbjct: 231 ITVKDVPDIDPQFLNLPNNAAVEENTGVGTTVFTVRARDPDTGVNDKITFSIDKTNAS-- 288 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKV----ARYTVLVKATDQASPV 126 D+FRID +G + A +DRE++ A + +KA++ V Sbjct: 289 -----------------DLFRIDTNTGIVSVNAEIDREELLNISATVVLKIKASETMPNV 331 Query: 127 SDRLSST-ATIHVNIIDDNDNYPQFSE---------KTYTVSVDEDISVTDNPVIAKIKA 176 + ++ST + ++I D+NDN P+F E + +V+E S IK Sbjct: 332 NGVIASTIGELQISIKDENDNSPEFYECEGEACMKKDNFEGNVNEHSSTGLAVANLNIKV 391 Query: 177 TDADVGANSAIRYAIIGGNTQMQFSIDSLSG-DVSLVKTL-------DYEQVRSYRLVIR 228 D D G NS + G + F + SG S V+ L DYE + + I Sbjct: 392 KDLDGGENSTFNLHLDGPDKDA-FRVSPTSGMGESTVQVLVKDPQAVDYEIKQIMNVQII 450 Query: 229 AQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV 288 A D + S T + I++ D NDN P F L++E V E+ G + + A DAD Sbjct: 451 AVDANADFTSTAT-VTIHLNDTNDNFPTFEKELYKEKVFEHCENGTIVATIIATDADAFD 509 Query: 289 NAELTYTMTDKDYTGNVDLPITIDPRSGWVY-TSGQ-LDRETQAKYQLLVTATDGGDPPR 346 ++TY + + ++ + ++G +Y T+G LD E Y L + A D G+ Sbjct: 510 EGKITYRLMPE----SIRSLFGVHEKTGTIYVTNGDTLDWEVTKSYTLTLQAFDSGN--N 563 Query: 347 SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH----YE 402 + T YE + E+E + + ATD DE L+ Y Sbjct: 564 TGTTVVEISILDINDNAPEMNRDIYEAFVQENEDFK---IQIQATDRDEPKTLNSEVQYR 620 Query: 403 ITGGNT-RGRFSITSQNG----RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMV 455 I+ +T F+I ++G +G + + +D Q L V A+D G RS +A V Sbjct: 621 ISEESTFSSNFTIGLESGLLTNKGDLD-REAIDISQNGVIQLIVIASDLGTPSRSSSAKV 679 Query: 456 QINITDANNYAPVF-ENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEIS 513 I++ DAN+ AP + +++PY V E G V V A D+D N +I +S++ Sbjct: 680 NISVGDANDNAPRYLDSSPYEFRVKESVK-GIYVGPVHAHDADQTDFNNRIFFSITDGSF 738 Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSG---YLLTVTARDGGVPSLSDTTDVEIS 570 + + + G IT + ++ + S Y L V A D G SD +V I Sbjct: 739 GSFIIYSEA--FSKGYRGNITVDPSVELDYESNRKEYTLKVQASDLG--QKSDVAEVHII 794 Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGS 629 V DVND P F + + E+ + V + D D N + YEL K + G+ Sbjct: 795 VEDVNDTPPEFPSGMIL-KVDENTTLPVPVDTIKGKDVDT--NHSLIYELVSTKCQCNGT 851 Query: 630 --------FVIDPASGVI-RTNKALDRESVATHDLKAVAID----GGTPPQSSTVIVHIK 676 F+++ +I T +D E L A +D G+ + +V I Sbjct: 852 IGPCPEEWFIVESNGDIIANTEYVIDYEKCDVVFLTARVVDIYTEVGSNSSEGSGVVTIN 911 Query: 677 IEDINDSPP--VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 I DIND+ P VF D I E GT++ A D D N Sbjct: 912 IVDINDNAPEFVFLQDFYVVVI-EKVDTGTSVARAYATDRDTADN 955 Score = 147 bits (355), Expect = 6e-33 Identities = 151/553 (27%), Positives = 245/553 (44%), Gaps = 54/553 (9%) Query: 373 VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432 V L ED G + ATD D+D L Y+I G N G F++ G ++T+ LD + Sbjct: 34 VILREDLRIGEYAFKIVATDPDDDP-LTYKIAGTNA-GFFTVEEHTG--IVTIKILLDRE 89 Query: 433 QERRYVLTVSATDSGGRSDTAM---VQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 + + T+ +T + + + IN+ DAN+ P+F PY V E+ +G + Sbjct: 90 TTQHFKCTLVSTYNAPTLFIQVRKTIYINVEDANDNIPIFNGLPYNKEVLENTTVGFVLF 149 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT-TNKLLDRETMSGYL 548 SATDSD G ++Y + +E V F I TG +T L E Y Sbjct: 150 TASATDSDFGQAGIVSYKI-----DEVVPDDKDMFSIVAATGVVTLVGNLNFTEKSPFYQ 204 Query: 549 LTVTARDGGVPSL------SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 + + A DGG S + I+V DV D +P F A + E+ VGT+V Sbjct: 205 IRINASDGGGELYGEEVVQSSSAIAFITVKDVPDIDPQFLNLPNNAAVEENTGVGTTVFT 264 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV----ATHDLKAV 658 V A D D G+N +I + +D K F ID +G++ N +DRE + AT LK Sbjct: 265 VRARDPDTGVNDKITFSID-KTNASDLFRIDTNTGIVSVNAEIDREELLNISATVVLKIK 323 Query: 659 AIDGGTPPQSSTVI------VHIKIEDINDSPPVF---------ESDCLTFYISENSPIG 703 A + T P + VI + I I+D ND+ P F + D ++E+S G Sbjct: 324 ASE--TMPNVNGVIASTIGELQISIKDENDNSPEFYECEGEACMKKDNFEGNVNEHSSTG 381 Query: 704 TTIG--EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD----LDYE 757 + I+ D D G N+ + + G D ++F + G ++ + +V +DYE Sbjct: 382 LAVANLNIKVKDLDGGENSTFNLHL-DGPDKDAFRVSPTSGMGESTVQVLVKDPQAVDYE 440 Query: 758 SPR-KKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRV 816 + +++ A+ + V I + D NDN P + ++ C + Sbjct: 441 IKQIMNVQIIAVDANADFTSTATVTIHLNDTNDNFPTFEKELYKEKVFEHCENGTIVATI 500 Query: 817 PAYDADVTD--KLQYRILSGNNANLILLNETTGS--MTLSPQLNTNVPKLATMEVSVTD- 871 A DAD D K+ YR++ + +L ++E TG+ +T L+ V K T+ + D Sbjct: 501 IATDADAFDEGKITYRLMPESIRSLFGVHEKTGTIYVTNGDTLDWEVTKSYTLTLQAFDS 560 Query: 872 GVNEIKAMMQLSV 884 G N ++++S+ Sbjct: 561 GNNTGTTVVEISI 573 Score = 56.8 bits (131), Expect = 8e-06 Identities = 61/205 (29%), Positives = 91/205 (44%), Gaps = 30/205 (14%) Query: 113 YTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV-I 171 YT+ V+A+D S A +H+ + D ND P+F + VDE+ ++ PV + Sbjct: 773 YTLKVQASDLGQK-----SDVAEVHIIVEDVNDTPPEFPSGMI-LKVDENTTL---PVPV 823 Query: 172 AKIKATDADVGANSAIRYAIIGGNTQMQ----------FSIDSLSGDV--SLVKTLDYEQ 219 IK D D N ++ Y ++ Q F ++S +GD+ + +DYE+ Sbjct: 824 DTIKGKDVDT--NHSLIYELVSTKCQCNGTIGPCPEEWFIVES-NGDIIANTEYVIDYEK 880 Query: 220 VRSYRLVIRAQD----GGSPSRSNTTQLLINIRDVNDNAPRF-YTSLFQESVSENVPIGY 274 L R D GS S + + INI D+NDNAP F + F V E V G Sbjct: 881 CDVVFLTARVVDIYTEVGSNSSEGSGVVTINIVDINDNAPEFVFLQDFYVVVIEKVDTGT 940 Query: 275 SIVRVQAYDADEGVNAELTYTMTDK 299 S+ R A D D N + T +K Sbjct: 941 SVARAYATDRDTADNNKKTKFQVNK 965 Score = 36.7 bits (81), Expect = 9.2 Identities = 19/58 (32%), Positives = 33/58 (56%), Gaps = 2/58 (3%) Query: 11 INVLDCNDHSPVFE-MQQYEASVREGASSGTTVLTLKATDQDIG-KNAEVEYTIELVT 66 IN++D ND++P F +Q + V E +GT+V ATD+D N + ++ + +T Sbjct: 910 INIVDINDNAPEFVFLQDFYVVVIEKVDTGTSVARAYATDRDTADNNKKTKFQVNKIT 967 >UniRef50_A7SHT2 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 470 Score = 242 bits (593), Expect = 8e-62 Identities = 169/491 (34%), Positives = 250/491 (50%), Gaps = 31/491 (6%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F ++ +G + SLDRE A Y+V V A+D + + I V+I D ND YP Sbjct: 1 FAVNKTTGDIKVTRSLDRESNASYSVTVMASD------GKFQAFLEIDVHIQDINDQYPV 54 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209 FS + Y+V++ E+ S PV+ ++ A D D G+NS + Y+I+ GN+ FSID +G + Sbjct: 55 FSPQNYSVAISEE-SWVRLPVL-QVTAVDMDSGSNSQVTYSIVDGNS--SFSIDPNTGQI 110 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPS--RSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 + +TLD+E RS+ L ++A+D G P+ + + INI D NDN P F + S++ Sbjct: 111 IVHRTLDFEVTRSFILRVQARDNGKPALVSRDYAYVTINITDENDNNPVFDKRSYNFSIT 170 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 E+V G V+A DAD G NA+L+Y++ D+D V +D +G + G +DRE Sbjct: 171 EDVAKGTVFGFVRANDADSGKNAKLSYSIPDED----VRKTFAVDEITGNLSVVGDIDRE 226 Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387 Y +V TD G PR A F P Y V ++E GT +V Sbjct: 227 RTGIYSFVVVVTDHGSSPRVGFAVVSVQVKDVNDNQPIFRPQNYTVRISEGTSVGTKIVW 286 Query: 388 LTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445 + A D D + + Y I GN F I G I + LD + +Y L + ATD Sbjct: 287 VHAHDEDIGPNALITYHIDSGNKESIFDIED----GTIVLNGTLDREVMDQYTLGILATD 342 Query: 446 SGG----RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501 +G D A+V I I D N+ P F + Y+ ++ ED IGT VL V A+D D+G N Sbjct: 343 NGEPPQLSRDPAIVVITIEDINDNYPEFNASVYSVNISEDTSIGTQVLSVYASDKDLGSN 402 Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG-YLLTVTARDGGVPS 560 A + Y + + +++ + F +N TGAI+T LD E+ + + V ARD G P+ Sbjct: 403 AHVQYFIIASANDDI----KRVFDVNKTTGAISTTSNLDFESANNRFQFQVEARDNGKPA 458 Query: 561 LSDTTDVEISV 571 L T VEI V Sbjct: 459 LYSQTTVEIMV 469 Score = 205 bits (501), Expect = 1e-50 Identities = 146/489 (29%), Positives = 227/489 (46%), Gaps = 31/489 (6%) Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259 F+++ +GD+ + ++LD E SY + + A DG + ++ ++I+D+ND P F Sbjct: 1 FAVNKTTGDIKVTRSLDRESNASYSVTVMASDGKFQA---FLEIDVHIQDINDQYPVFSP 57 Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319 + ++SE + +++V A D D G N+++TY++ D GN +IDP +G + Sbjct: 58 QNYSVAISEESWVRLPVLQVTAVDMDSGSNSQVTYSIVD----GNSS--FSIDPNTGQII 111 Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRSAT--ATXXXXXXXXXXXXXXFMPGQYEVELAE 377 LD E + L V A D G P + A F Y + E Sbjct: 112 VHRTLDFEVTRSFILRVQARDNGKPALVSRDYAYVTINITDENDNNPVFDKRSYNFSITE 171 Query: 378 DEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435 D GT + A DAD ++ +L Y I + R F++ G ++V +D ++ Sbjct: 172 DVAKGTVFGFVRANDADSGKNAKLSYSIPDEDVRKTFAVDEITGN--LSVVGDIDRERTG 229 Query: 436 RYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 Y V TD G R A+V + + D N+ P+F YT + E +GT ++ V A Sbjct: 230 IYSFVVVVTDHGSSPRVGFAVVSVQVKDVNDNQPIFRPQNYTVRISEGTSVGTKIVWVHA 289 Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553 D D+G NA ITY + S +++ + + + G I N LDRE M Y L + A Sbjct: 290 HDEDIGPNALITYHIDS---------GNKESIFDIEDGTIVLNGTLDREVMDQYTLGILA 340 Query: 554 RDGG-VPSLS-DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG 611 D G P LS D V I++ D+NDN P F +Y+ NI ED +GT V V A+D D+G Sbjct: 341 TDNGEPPQLSRDPAIVVITIEDINDNYPEFNASVYSVNISEDTSIGTQVLSVYASDKDLG 400 Query: 612 LNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATH-DLKAVAIDGGTPPQS 668 N + Y + D + F ++ +G I T LD ES + A D G P Sbjct: 401 SNAHVQYFIIASANDDIKRVFDVNKTTGAISTTSNLDFESANNRFQFQVEARDNGKPALY 460 Query: 669 STVIVHIKI 677 S V I + Sbjct: 461 SQTTVEIMV 469 Score = 200 bits (489), Expect = 3e-49 Identities = 140/448 (31%), Positives = 220/448 (49%), Gaps = 30/448 (6%) Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 G I V + LD + Y +TV A+D G + ++I D N+ PVF Y+ ++ E Sbjct: 8 GDIKVTRSLDRESNASYSVTVMASD-GKFQAFLEIDVHIQDINDQYPVFSPQNYSVAISE 66 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 ++ + VL V+A D D G N+Q+TYS + + F I+P TG I ++ LD Sbjct: 67 ESWVRLPVLQVTAVDMDSGSNSQVTYS---------IVDGNSSFSIDPNTGQIIVHRTLD 117 Query: 541 RETMSGYLLTVTARDGGVPSL--SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 E ++L V ARD G P+L D V I++ D NDN PVF ++ Y +I ED GT Sbjct: 118 FEVTRSFILRVQARDNGKPALVSRDYAYVTINITDENDNNPVFDKRSYNFSITEDVAKGT 177 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 V A DAD G N ++ Y + +D + +F +D +G + +DRE + V Sbjct: 178 VFGFVRANDADSGKNAKLSYSIPDEDVRK-TFAVDEITGNLSVVGDIDRERTGIYSFVVV 236 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 D G+ P+ +V ++++D+ND+ P+F T ISE + +GT I + AHD D GP Sbjct: 237 VTDHGSSPRVGFAVVSVQVKDVNDNQPIFRPQNYTVRISEGTSVGTKIVWVHAHDEDIGP 296 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS----PPL 774 NA++ Y I G+ + F +E +V LD E +Y L I A P L Sbjct: 297 NALITYHIDSGNKESIFDIE------DGTIVLNGTLDRE-VMDQYTLGILATDNGEPPQL 349 Query: 775 WNDVRVEIL-VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRI 831 D + ++ + D+NDN P N +D V A D D+ +QY I Sbjct: 350 SRDPAIVVITIEDINDNYPEFNASVYSVNISEDTSIGTQVLSVYASDKDLGSNAHVQYFI 409 Query: 832 LSGNNANL---ILLNETTGSMTLSPQLN 856 ++ N ++ +N+TTG+++ + L+ Sbjct: 410 IASANDDIKRVFDVNKTTGAISTTSNLD 437 Score = 185 bits (450), Expect = 2e-44 Identities = 130/443 (29%), Positives = 205/443 (46%), Gaps = 36/443 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +++ D ND PVF Q Y ++ E + VL + A D D G N++V Y+I V ++ Sbjct: 43 VHIQDINDQYPVFSPQNYSVAISEESWVRLPVLQVTAVDMDSGSNSQVTYSI--VDGNS- 99 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F ID +G ++ +LD E + + V+A D P Sbjct: 100 ------------------SFSIDPNTGQIIVHRTLDFEVTRSFILRVQARDNGKPALVS- 140 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 A + +NI D+NDN P F +++Y S+ ED V V ++A DAD G N+ + Y+ Sbjct: 141 RDYAYVTINITDENDNNPVFDKRSYNFSITED--VAKGTVFGFVRANDADSGKNAKLSYS 198 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I + + F++D ++G++S+V +D E+ Y V+ D GS R + + ++DV Sbjct: 199 IPDEDVRKTFAVDEITGNLSVVGDIDRERTGIYSFVVVVTDHGSSPRVGFAVVSVQVKDV 258 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F + +SE +G IV V A+D D G NA +TY + +GN + Sbjct: 259 NDNQPIFRPQNYTVRISEGTSVGTKIVWVHAHDEDIGPNALITYHID----SGNKE--SI 312 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA--TATXXXXXXXXXXXXXXFMP 368 D G + +G LDRE +Y L + ATD G+PP+ + A F Sbjct: 313 FDIEDGTIVLNGTLDREVMDQYTLGILATDNGEPPQLSRDPAIVVITIEDINDNYPEFNA 372 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYE---ITGGNTRGRFSITSQNGRGLITV 425 Y V ++ED GT V+++ A+D D + H + I N + G I+ Sbjct: 373 SVYSVNISEDTSIGTQVLSVYASDKDLGSNAHVQYFIIASANDDIKRVFDVNKTTGAIST 432 Query: 426 AQPLDFKQ-ERRYVLTVSATDSG 447 LDF+ R+ V A D+G Sbjct: 433 TSNLDFESANNRFQFQVEARDNG 455 Score = 158 bits (383), Expect = 2e-36 Identities = 110/337 (32%), Positives = 167/337 (49%), Gaps = 30/337 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 IN+ D ND++PVF+ + Y S+ E + GT ++A D D GKNA++ Y+I Sbjct: 148 INITDENDNNPVFDKRSYNFSITEDVAKGTVFGFVRANDADSGKNAKLSYSI-------- 199 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P++ V+ F +D +G L +DRE+ Y+ +V TD S S R+ Sbjct: 200 -PDE----------DVRKTFAVDEITGNLSVVGDIDRERTGIYSFVVVVTDHGS--SPRV 246 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 A + V + D NDN P F + YTV + E SV I + A D D+G N+ I Y Sbjct: 247 -GFAVVSVQVKDVNDNQPIFRPQNYTVRISEGTSV--GTKIVWVHAHDEDIGPNALITYH 303 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR--SNTTQLLINIR 248 I GN + F I+ G + L TLD E + Y L I A D G P + + ++I I Sbjct: 304 IDSGNKESIFDIE--DGTIVLNGTLDREVMDQYTLGILATDNGEPPQLSRDPAIVVITIE 361 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D+NDN P F S++ ++SE+ IG ++ V A D D G NA + Y + ++ Sbjct: 362 DINDNYPEFNASVYSVNISEDTSIGTQVLSVYASDKDLGSNAHVQYFII-ASANDDIKRV 420 Query: 309 ITIDPRSGWVYTSGQLDRET-QAKYQLLVTATDGGDP 344 ++ +G + T+ LD E+ ++Q V A D G P Sbjct: 421 FDVNKTTGAISTTSNLDFESANNRFQFQVEARDNGKP 457 Score = 88.6 bits (210), Expect = 2e-15 Identities = 75/249 (30%), Positives = 122/249 (48%), Gaps = 17/249 (6%) Query: 630 FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES 689 F ++ +G I+ ++LDRES A++ + +A DG + + + + I+DIND PVF Sbjct: 1 FAVNKTTGDIKVTRSLDRESNASYSVTVMASDGKF---QAFLEIDVHIQDINDQYPVFSP 57 Query: 690 DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV 749 + ISE S + + ++ A D D G N+ V YSI G+ +SFS++ G +++ Sbjct: 58 QNYSVAISEESWVRLPVLQVTAVDMDSGSNSQVTYSIVDGN--SSFSIDPNTG----QII 111 Query: 750 TMVDLDYESPRKKYELVIRA---ASPPLWND--VRVEILVTDVNDNAPVMKDFQIIFNNY 804 LD+E R + L ++A P L + V I +TD NDN PV F+ Sbjct: 112 VHRTLDFEVTRS-FILRVQARDNGKPALVSRDYAYVTINITDENDNNPVFDKRSYNFSIT 170 Query: 805 KDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKL 862 +D FG V A DAD KL Y I + ++E TG++++ ++ + Sbjct: 171 EDVAKGTVFGFVRANDADSGKNAKLSYSIPDEDVRKTFAVDEITGNLSVVGDIDRERTGI 230 Query: 863 ATMEVSVTD 871 + V VTD Sbjct: 231 YSFVVVVTD 239 >UniRef50_Q8N6Y1 Cluster: Protocadherin-20 precursor; n=28; Euteleostomi|Rep: Protocadherin-20 precursor - Homo sapiens (Human) Length = 924 Score = 242 bits (593), Expect = 8e-62 Identities = 186/669 (27%), Positives = 303/669 (45%), Gaps = 28/669 (4%) Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195 + + I D NDN PQF +V V E+ V I A D DVG N Y ++ + Sbjct: 168 VKIAIRDINDNAPQFPVSQISVWVPENAPVNTRLAIEH-PAVDPDVGINGVQTYRLLDYH 226 Query: 196 TQMQFSID-SLSGD----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 ++ + +G+ + ++ LD E Y +I A+DGGSP + L I I D+ Sbjct: 227 GMFTLDVEENENGERTPYLIVMGALDRETQDQYVSIIIAEDGGSPPLLGSATLTIGISDI 286 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F S +V N +G I VQA D D G NA++TY+ + K + DL Sbjct: 287 NDNCPLFTDSQINVTVYGNATVGTPIAAVQAVDKDLGTNAQITYSYSQKVPQASKDL-FH 345 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX--XXXXXFMP 368 +D +G + ++ ++L + A G P TA ++ Sbjct: 346 LDENTGVIKLFSKIGGSVLESHKLTILANGPGCIPAVITALVSIIKVIFRPPEIVPRYIA 405 Query: 369 GQYE--VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 + + V L E EP TP+ T D + +++ + G N L+ Sbjct: 406 NEIDGVVYLKELEPVNTPIAFFTIRDPEGKYKVNCYLDGEGPFRLSPYKPYNNEYLLETT 465 Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 +P+D++ ++ Y + V A +S G ++++ + D N+ AP+F ++ E+ Sbjct: 466 KPMDYELQQFYEVAVVAWNSEGFHVKRVIKVQLLDDNDNAPIFLQPLIELTIEENNSPNA 525 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 + + ATD+D Q++Y L + + F ++ TG +T + LDRE Sbjct: 526 FLTKLYATDADSEERGQVSYFLGPDAPS--------YFSLDSVTGILTVSTQLDREEKEK 577 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y TV A D G P V ++V+D NDN P F + ++ + E+ + + T Sbjct: 578 YRYTVRAVDCGKPPRESVATVALTVLDKNDNSPRFINKDFSFFVPENFPGYGEIGVISVT 637 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 DAD G NG + + + FVID G++R +LDRE +++ L A+DGG P Sbjct: 638 DADAGRNGWVALSV---VNQSDIFVIDTGKGMLRAKVSLDREQQSSYTLWVEAVDGGEPA 694 Query: 667 QSSTVIVHIKIEDINDSPP--VFESDCLTFYISENSPI-GTTIGEIRAHDPDEGPNAVVH 723 SST + I + DIND+PP +F +++ + S + G+ + E+ A D D G NAV+ Sbjct: 695 LSSTAKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGSPVTEVYAVDKDTGMNAVIA 754 Query: 724 YSIKG--GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE 781 YSI G G SF ++ + G+ E ++ DY R ++ PL + V V Sbjct: 755 YSIIGRRGPRPESFRIDPKTGNITLE-EALLQTDYGLHRLLVKVSDHGYPEPLHSTVMVN 813 Query: 782 ILVTDVNDN 790 + V D N Sbjct: 814 LFVNDTVSN 822 Score = 182 bits (443), Expect = 1e-43 Identities = 191/703 (27%), Positives = 302/703 (42%), Gaps = 66/703 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTV-LTLKATDQDIGKNAEVEYTI-ELVTA 67 +I + D ND++P F + Q V E A T + + A D D+G N Y + + Sbjct: 169 KIAIRDINDNAPQFPVSQISVWVPENAPVNTRLAIEHPAVDPDVGINGVQTYRLLDYHGM 228 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 TL+ E+ R+ L+ +LDRE +Y ++ A D SP Sbjct: 229 FTLDVEENENGE---------------RTPYLIVMGALDRETQDQYVSIIIAEDGGSPP- 272 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 L +AT+ + I D NDN P F++ V+V + +V IA ++A D D+G N+ I Sbjct: 273 --LLGSATLTIGISDINDNCPLFTDSQINVTVYGNATV--GTPIAAVQAVDKDLGTNAQI 328 Query: 188 RYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS-PSRSNTTQL 243 Y+ + ++ F +D +G + L + + S++L I A G P+ Sbjct: 329 TYSYSQKVPQASKDLFHLDENTGVIKLFSKIGGSVLESHKLTILANGPGCIPAVITALVS 388 Query: 244 LIN-IRDVNDNAPRFYTS------LFQESVSENVPIGYSIVR--VQAYDADEGVNAELTY 294 +I I + PR+ + +E N PI + +R Y + ++ E + Sbjct: 389 IIKVIFRPPEIVPRYIANEIDGVVYLKELEPVNTPIAFFTIRDPEGKYKVNCYLDGEGPF 448 Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354 ++ N L T P +D E Q Y++ V A + Sbjct: 449 RLSPYKPYNNEYLLETTKP----------MDYELQQFYEVAVVAWN--SEGFHVKRVIKV 496 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYE-ITGGNTRGRFS 413 F+ E+ + E+ P + L ATDAD + R G + FS Sbjct: 497 QLLDDNDNAPIFLQPLIELTIEENNSPNAFLTKLYATDADSEERGQVSYFLGPDAPSYFS 556 Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFEN 471 + S G++TV+ LD +++ +Y TV A D G R A V + + D N+ +P F N Sbjct: 557 LDSVT--GILTVSTQLDREEKEKYRYTVRAVDCGKPPRESVATVALTVLDKNDNSPRFIN 614 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 ++ V E+ P + V+S TD+D G N + S V + FVI+ G Sbjct: 615 KDFSFFVPENFPGYGEIGVISVTDADAGRNGWVALS---------VVNQSDIFVIDTGKG 665 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP--VFKQ-QLYTA 588 + LDRE S Y L V A DGG P+LS T + I ++D+NDN P +F Q + Sbjct: 666 MLRAKVSLDREQQSSYTLWVEAVDGGEPALSSTAKITILLLDINDNPPLVLFPQSNMSYL 725 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGVIRTNKALDR 647 ++ L G+ V++V A D D G+N I Y + + SF IDP +G I +AL + Sbjct: 726 LVLPSTLPGSPVTEVYAVDKDTGMNAVIAYSIIGRRGPRPESFRIDPKTGNITLEEALLQ 785 Query: 648 ESVATHDLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFES 689 H L D G P P STV+V++ + D + ES Sbjct: 786 TDYGLHRLLVKVSDHGYPEPLHSTVMVNLFVNDTVSNESYIES 828 Score = 169 bits (410), Expect = 1e-39 Identities = 166/647 (25%), Positives = 271/647 (41%), Gaps = 37/647 (5%) Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSI-VRVQAYDADEGVNAELTYTMTDKDYTG 303 I IRD+NDNAP+F S V EN P+ + + A D D G+N TY + D Y G Sbjct: 170 IAIRDINDNAPQFPVSQISVWVPENAPVNTRLAIEHPAVDPDVGINGVQTYRLLD--YHG 227 Query: 304 NVDLPITIDP---RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 L + + R+ ++ G LDRETQ +Y ++ A DGG PP +AT Sbjct: 228 MFTLDVEENENGERTPYLIVMGALDRETQDQYVSIIIAEDGGSPPLLGSATLTIGISDIN 287 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITS-Q 417 F Q V + + GTP+ + A D D + ++ Y + + + Sbjct: 288 DNCPLFTDSQINVTVYGNATVGTPIAAVQAVDKDLGTNAQITYSYSQKVPQASKDLFHLD 347 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQIN--ITDANNYAPVFENAP 473 G+I + + + LT+ A G TA+V I I P + Sbjct: 348 ENTGVIKLFSKIGGSVLESHKLTILANGPGCIPAVITALVSIIKVIFRPPEIVPRYIANE 407 Query: 474 YTASVF--EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 V+ E P+ T + + D + Y ++ + E N + Sbjct: 408 IDGVVYLKELEPVNTPIAFFTIRDPEG------KYKVNCYLDGEGPFRLSPYKPYNNEY- 460 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 + T K +D E Y + V A + +++ ++D NDN P+F Q L I Sbjct: 461 LLETTKPMDYELQQFYEVAVVAWNS--EGFHVKRVIKVQLLDDNDNAPIFLQPLIELTIE 518 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA 651 E+ ++++ ATDAD G++ Y L P F +D +G++ + LDRE Sbjct: 519 ENNSPNAFLTKLYATDADSEERGQVSYFLGPD--APSYFSLDSVTGILTVSTQLDREEKE 576 Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711 + A+D G PP+ S V + + D ND+ P F + +F++ EN P IG I Sbjct: 577 KYRYTVRAVDCGKPPRESVATVALTVLDKNDNSPRFINKDFSFFVPENFPGYGEIGVISV 636 Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771 D D G N V S+ + S+ F ++T +G +A++ +D + +S + + Sbjct: 637 TDADAGRNGWVALSVV--NQSDIFVIDTGKGMLRAKV--SLDREQQSSYTLWVEAVDGGE 692 Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN---YKDCFPVGPFGRVPAYDAD--VTDK 826 P L + ++ IL+ D+NDN P++ Q + P P V A D D + Sbjct: 693 PALSSTAKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGSPVTEVYAVDKDTGMNAV 752 Query: 827 LQYRILS--GNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + Y I+ G ++ TG++TL L L + V V+D Sbjct: 753 IAYSIIGRRGPRPESFRIDPKTGNITLEEALLQTDYGLHRLLVKVSD 799 Score = 89.8 bits (213), Expect = 9e-16 Identities = 78/266 (29%), Positives = 126/266 (47%), Gaps = 33/266 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND+SP F + + V E + + TD D G+N V ++ + Sbjct: 600 LTVLDKNDNSPRFINKDFSFFVPENFPGYGEIGVISVTDADAGRNGWVALSV-------V 652 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N D +F ID G L + SLDRE+ + YT+ V+A D P L Sbjct: 653 NQSD--------------IFVIDTGKGMLRAKVSLDREQQSSYTLWVEAVDGGEPA---L 695 Query: 131 SSTATIHVNIIDDNDNYP--QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 SSTA I + ++D NDN P F + + + ++ +PV ++ A D D G N+ I Sbjct: 696 SSTAKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGSPV-TEVYAVDKDTGMNAVIA 754 Query: 189 YAIIG--GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 Y+IIG G F ID +G+++L + L +RL+++ D G P ++T +++N Sbjct: 755 YSIIGRRGPRPESFRIDPKTGNITLEEALLQTDYGLHRLLVKVSDHGYPEPLHST-VMVN 813 Query: 247 IRDVNDNAPR--FYTSLFQESVSENV 270 + VND + SL ++ N+ Sbjct: 814 L-FVNDTVSNESYIESLLRKEPEINI 838 Score = 78.2 bits (184), Expect = 3e-12 Identities = 62/226 (27%), Positives = 105/226 (46%), Gaps = 10/226 (4%) Query: 671 VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG-EIRAHDPDEGPNAVVHYSIKGG 729 V V I I DIND+ P F ++ ++ EN+P+ T + E A DPD G N V Y + Sbjct: 166 VKVKIAIRDINDNAPQFPVSQISVWVPENAPVNTRLAIEHPAVDPDVGINGVQTYRLLDY 225 Query: 730 DDSNSFSLETRQGSDKAE-LVTMVDLDYESPRKKYELVIR--AASPPLWNDVRVEILVTD 786 + +E + ++ L+ M LD E+ + ++I SPPL + I ++D Sbjct: 226 HGMFTLDVEENENGERTPYLIVMGALDRETQDQYVSIIIAEDGGSPPLLGSATLTIGISD 285 Query: 787 VNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQY-----RILSGNNANLIL 841 +NDN P+ D QI Y + P V A D D+ Q + + + +L Sbjct: 286 INDNCPLFTDSQINVTVYGNATVGTPIAAVQAVDKDLGTNAQITYSYSQKVPQASKDLFH 345 Query: 842 LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887 L+E TG + L ++ +V + + + + +G I A++ V +I Sbjct: 346 LDENTGVIKLFSKIGGSVLESHKLTI-LANGPGCIPAVITALVSII 390 >UniRef50_UPI000155BF0A Cluster: PREDICTED: similar to protocadherin gamma B5; n=2; Ornithorhynchus anatinus|Rep: PREDICTED: similar to protocadherin gamma B5 - Ornithorhynchus anatinus Length = 1443 Score = 242 bits (592), Expect = 1e-61 Identities = 188/608 (30%), Positives = 274/608 (45%), Gaps = 28/608 (4%) Query: 87 QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146 + +F + SG LL +DRE++ TV +A V + + ++V I D NDN Sbjct: 72 KQLFTVSADSGDLLVSHRIDREQICGKTVRCSILLEA--VVENPLNVFHVNVEIQDINDN 129 Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206 P+F + + E S A A D DVG NS Y ++ N F + Sbjct: 130 PPRFRRNHIDLEISE--SAVSGASFALEPAQDPDVGINSLKNY-LLSTNPNFSFDVKETK 186 Query: 207 -----GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261 ++ + K LD E SY LV+ A DGG P S T ++ IN+ D NDNAP F + Sbjct: 187 DGNKYAELIVGKPLDRETQNSYHLVLTAVDGGDPVLSGTVEIRINVTDANDNAPVFSQDV 246 Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321 ++ S+ E++P G ++RV+A D DEG NA +T+ ++ T V +DP SG + T Sbjct: 247 YKVSLRESLPPGSPVLRVEATDKDEGANARVTFAFSNVAQT--VRHAFALDPVSGEISTK 304 Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381 G LD E Y L++ A DGG T F + ED Sbjct: 305 GILDFEGIKGYSLVLEAKDGGGLVTQCTVEIEILDENDNAPEVTFT--SISSPIPEDSEL 362 Query: 382 GTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440 GT + + D D DN G + +S N L+T LD +Q Y +T Sbjct: 363 GTVIALIRTRDRDSGDNGAVTCRIEGEIPFKIVSSSNNYYKLMT-DSVLDREQTAEYNIT 421 Query: 441 VSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498 ++ATD G + + + + + D N+ PVF + Y A V E+ G ++ VSA+D D+ Sbjct: 422 ITATDRGNPPLTTSKTISLLVADVNDNPPVFPHTTYVAYVPENNRPGASIFRVSASDRDL 481 Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558 NA+I+YSL S+E+ IN +G I + D E + L V A+D G Sbjct: 482 DSNARISYSLLD--SSESELPLSSSVSINSHSGDIYAQRSFDYEQFRAFELHVQAQDSGS 539 Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQQLYTAN-------IMEDALVGTSVSQVGATDADVG 611 P L V + +VD NDN P + + A G VS+V A DAD G Sbjct: 540 PPLRANVTVRVFIVDQNDNAPRILYPALEPDGSALFDMVPRSAEPGYLVSKVVAVDADSG 599 Query: 612 LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671 N + Y + + + G F + +G IRT +AL + H L DGG PP SSTV Sbjct: 600 PNAWLAYHV-LQASDPGLFSLGLRTGEIRTARALADGDPSRHRLLVAVRDGGQPPLSSTV 658 Query: 672 IVHIKIED 679 +H+ D Sbjct: 659 ALHLVFAD 666 Score = 219 bits (534), Expect = 1e-54 Identities = 172/581 (29%), Positives = 270/581 (46%), Gaps = 36/581 (6%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQ---NGRG 421 F ++E++E G A D D N L + N F + N Sbjct: 133 FRRNHIDLEISESAVSGASFALEPAQDPDVGINSLKNYLLSTNPNFSFDVKETKDGNKYA 192 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVF 479 + V +PLD + + Y L ++A D G S T ++IN+TDAN+ APVF Y S+ Sbjct: 193 ELIVGKPLDRETQNSYHLVLTAVDGGDPVLSGTVEIRINVTDANDNAPVFSQDVYKVSLR 252 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E P G+ VL V ATD D G NA++T++ S+ + V H F ++P +G I+T +L Sbjct: 253 ESLPPGSPVLRVEATDKDEGANARVTFAFSNVA--QTVRH---AFALDPVSGEISTKGIL 307 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 D E + GY L + A+DGG L VEI ++D NDN P ++ I ED+ +GT Sbjct: 308 DFEGIKGYSLVLEAKDGG--GLVTQCTVEIEILDENDNAPEVTFTSISSPIPEDSELGTV 365 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG---VIRTNKALDRESVATHDLK 656 ++ + D D G NG + ++ E F I +S + T+ LDRE A +++ Sbjct: 366 IALIRTRDRDSGDNGAVTCRIEG----EIPFKIVSSSNNYYKLMTDSVLDREQTAEYNIT 421 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 A D G PP +++ + + + D+ND+PPVF Y+ EN+ G +I + A D D Sbjct: 422 ITATDRGNPPLTTSKTISLLVADVNDNPPVFPHTTYVAYVPENNRPGASIFRVSASDRDL 481 Query: 717 GPNAVVHYSIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASP 772 NA + YS+ +S S S ++ DYE R +EL ++A SP Sbjct: 482 DSNARISYSLLDSSESELPLSSSVSINSHSGDIYAQRSFDYEQFR-AFELHVQAQDSGSP 540 Query: 773 PLWNDVRVEILVTDVNDNAP------VMKDFQIIFNNY-KDCFPVGPFGRVPAYDADVTD 825 PL +V V + + D NDNAP + D +F+ + P +V A DAD Sbjct: 541 PLRANVTVRVFIVDQNDNAPRILYPALEPDGSALFDMVPRSAEPGYLVSKVVAVDADSGP 600 Query: 826 K--LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLS 883 L Y +L ++ L L TG + + L P + V+V DG + ++ Sbjct: 601 NAWLAYHVLQASDPGLFSLGLRTGEIRTARALADGDPSRHRLLVAVRDG-GQPPLSSTVA 659 Query: 884 VRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAII 924 + L+ + L ++ L+D +A + FF+ AI+ Sbjct: 660 LHLVFADSLQEALP-ELSDRSAPSDSQSKVNFFLVIALAIV 699 Score = 164 bits (398), Expect = 4e-38 Identities = 136/468 (29%), Positives = 212/468 (45%), Gaps = 42/468 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +INV D ND++PVF Y+ S+RE G+ VL ++ATD+D G NA V + V A T Sbjct: 229 RINVTDANDNAPVFSQDVYKVSLRESLPPGSPVLRVEATDKDEGANARVTFAFSNV-AQT 287 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 V+ F +D SG + T+ LD E + Y+++++A D Sbjct: 288 ----------------VRHAFALDPVSGEISTKGILDFEGIKGYSLVLEAKDGGG----- 326 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L + T+ + I+D+NDN P+ + + + + ED + VIA I+ D D G N A+ Sbjct: 327 LVTQCTVEIEILDENDNAPEVTFTSISSPIPEDSEL--GTVIALIRTRDRDSGDNGAVTC 384 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 I G ++ F I S S + + T LD EQ Y + I A D G+P + + + + Sbjct: 385 RIEG---EIPFKIVSSSNNYYKLMTDSVLDREQTAEYNITITATDRGNPPLTTSKTISLL 441 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NV 305 + DVNDN P F + + V EN G SI RV A D D NA ++Y++ D + + Sbjct: 442 VADVNDNPPVFPHTTYVAYVPENNRPGASIFRVSASDRDLDSNARISYSLLDSSESELPL 501 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 ++I+ SG +Y D E ++L V A D G PP A T Sbjct: 502 SSSVSINSHSGDIYAQRSFDYEQFRAFELHVQAQDSGSPPLRANVTVRVFIVDQNDNAPR 561 Query: 366 FMPGQYEVE-------LAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITS 416 + E + + PG V + A DAD L Y + + G FS+ Sbjct: 562 ILYPALEPDGSALFDMVPRSAEPGYLVSKVVAVDADSGPNAWLAYHVLQASDPGLFSLGL 621 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANN 464 + G I A+ L R+ L V+ D G ++ V +++ A++ Sbjct: 622 RTGE--IRTARALADGDPSRHRLLVAVRDGGQPPLSSTVALHLVFADS 667 Score = 92.3 bits (219), Expect = 2e-16 Identities = 69/228 (30%), Positives = 111/228 (48%), Gaps = 8/228 (3%) Query: 601 SQVGATDADVGLNGR-IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK-AV 658 S VG D+GLN R + E+ F + SG + + +DRE + ++ ++ Sbjct: 45 SVVGHLARDLGLNIREVSGRKLRVSAEKQLFTVSADSGDLLVSHRIDREQICGKTVRCSI 104 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 ++ + V+++I+DIND+PP F + + ISE++ G + A DPD G Sbjct: 105 LLEAVVENPLNVFHVNVEIQDINDNPPRFRRNHIDLEISESAVSGASFALEPAQDPDVGI 164 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLW 775 N++ +Y + + + ET+ G+ AEL+ LD E+ + Y LV+ A P L Sbjct: 165 NSLKNYLLSTNPNFSFDVKETKDGNKYAELIVGKPLDRET-QNSYHLVLTAVDGGDPVLS 223 Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD 822 V + I VTD NDNAPV + + ++ P G P RV A D D Sbjct: 224 GTVEIRINVTDANDNAPVFSQ-DVYKVSLRESLPPGSPVLRVEATDKD 270 Score = 91.5 bits (217), Expect = 3e-16 Identities = 62/231 (26%), Positives = 113/231 (48%), Gaps = 20/231 (8%) Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 S LSS T+ +N+ D NDN P F +++ V V E+ ++ + A+D D G N Sbjct: 1022 SPPLSSQRTVSLNVSDVNDNAPAFFRRSHEVFVQENNR--PGVLLCSLAASDPDSGLNGL 1079 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 I Y+++ + +G V ++ DYEQ ++ + ++A+D G P S+T + + Sbjct: 1080 IAYSLLEPRGRE-------TGAVHAARSFDYEQTQTLQFEVQARDRGEPPLSSTVTVRLF 1132 Query: 247 IRDVNDNAPRFYT------SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 I DVNDNAP +L +++ + G+ + +V A D D G NA ++Y + Sbjct: 1133 ILDVNDNAPAVLRPQARPGALCPQALPPSASAGHLVTKVTAVDLDSGYNAWVSYQL---- 1188 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 + + +G + T+G + + + +L++ D G+PP S + T Sbjct: 1189 FEAPDPTLFAVSRYAGEIRTAGPIPADLPPQ-RLVIMVQDSGNPPLSTSVT 1238 Score = 89.4 bits (212), Expect = 1e-15 Identities = 68/237 (28%), Positives = 106/237 (44%), Gaps = 19/237 (8%) Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616 G P LS V ++V DVNDN P F ++ + + E+ G + + A+D D GLNG I Sbjct: 1021 GSPPLSSQRTVSLNVSDVNDNAPAFFRRSHEVFVQENNRPGVLLCSLAASDPDSGLNGLI 1080 Query: 617 HYE-LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675 Y L+P+ RE +G + ++ D E T + A D G PP SSTV V + Sbjct: 1081 AYSLLEPRGRE---------TGAVHAARSFDYEQTQTLQFEVQARDRGEPPLSSTVTVRL 1131 Query: 676 KIEDINDSPPVF------ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729 I D+ND+ P + ++ G + ++ A D D G NA V Y + Sbjct: 1132 FILDVNDNAPAVLRPQARPGALCPQALPPSASAGHLVTKVTAVDLDSGYNAWVSYQLFEA 1191 Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTD 786 D F++ G + DL P++ +V + +PPL V + + + D Sbjct: 1192 PDPTLFAVSRYAGEIRTAGPIPADL---PPQRLVIMVQDSGNPPLSTSVTLLVSLED 1245 Score = 87.8 bits (208), Expect = 4e-15 Identities = 72/244 (29%), Positives = 107/244 (43%), Gaps = 22/244 (9%) Query: 442 SATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501 S S S V +N++D N+ AP F + V E+ G + ++A+D D G+N Sbjct: 1018 STAGSPPLSSQRTVSLNVSDVNDNAPAFFRRSHEVFVQENNRPGVLLCSLAASDPDSGLN 1077 Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL 561 I YSL E TGA+ + D E V ARD G P L Sbjct: 1078 GLIAYSLLEPRGRE--------------TGAVHAARSFDYEQTQTLQFEVQARDRGEPPL 1123 Query: 562 SDTTDVEISVVDVNDNEP-VFKQQLYTANIMEDAL-----VGTSVSQVGATDADVGLNGR 615 S T V + ++DVNDN P V + Q + AL G V++V A D D G N Sbjct: 1124 SSTVTVRLFILDVNDNAPAVLRPQARPGALCPQALPPSASAGHLVTKVTAVDLDSGYNAW 1183 Query: 616 IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675 + Y+L + + F + +G IRT + + + L + D G PP S++V + + Sbjct: 1184 VSYQLF-EAPDPTLFAVSRYAGEIRTAGPIPAD-LPPQRLVIMVQDSGNPPLSTSVTLLV 1241 Query: 676 KIED 679 +ED Sbjct: 1242 SLED 1245 Score = 70.9 bits (166), Expect = 5e-10 Identities = 62/243 (25%), Positives = 104/243 (42%), Gaps = 34/243 (13%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NV D ND++P F + +E V+E G + +L A+D D G N + Y++ L Sbjct: 1033 LNVSDVNDNAPAFFRRSHEVFVQENNRPGVLLCSLAASDPDSGLNGLIAYSL-------L 1085 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P +GA+ S D E+ V+A D+ P L Sbjct: 1086 EPRGR-------------------ETGAVHAARSFDYEQTQTLQFEVQARDRGEPP---L 1123 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSV--DEDI--SVTDNPVIAKIKATDADVGANSA 186 SST T+ + I+D NDN P + + S + ++ K+ A D D G N+ Sbjct: 1124 SSTVTVRLFILDVNDNAPAVLRPQARPGALCPQALPPSASAGHLVTKVTAVDLDSGYNAW 1183 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 + Y + F++ +G++ + + + RLVI QD G+P S + LL++ Sbjct: 1184 VSYQLFEAPDPTLFAVSRYAGEIRTAGPIPAD-LPPQRLVIMVQDSGNPPLSTSVTLLVS 1242 Query: 247 IRD 249 + D Sbjct: 1243 LED 1245 Score = 68.5 bits (160), Expect = 2e-09 Identities = 43/134 (32%), Positives = 66/134 (49%), Gaps = 13/134 (9%) Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 G+PP SS V + + D+ND+ P F ++ EN+ G + + A DPD G N ++ Sbjct: 1021 GSPPLSSQRTVSLNVSDVNDNAPAFFRRSHEVFVQENNRPGVLLCSLAASDPDSGLNGLI 1080 Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIR-AASPPLWNDVRV 780 YS+ LE R G + + DYE + ++E+ R PPL + V V Sbjct: 1081 AYSL----------LEPR-GRETGAVHAARSFDYEQTQTLQFEVQARDRGEPPLSSTVTV 1129 Query: 781 EILVTDVNDNAPVM 794 + + DVNDNAP + Sbjct: 1130 RLFILDVNDNAPAV 1143 Score = 58.8 bits (136), Expect = 2e-06 Identities = 49/171 (28%), Positives = 74/171 (43%), Gaps = 14/171 (8%) Query: 181 VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240 + A A R A G T + F L+ +S +TL + + GSP S+ Sbjct: 972 LAAPRAKRAAAPGRQTSLPFG---LAARLSRGQTLKPALSSRCQTDSQRSTAGSPPLSSQ 1028 Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 + +N+ DVNDNAP F+ + V EN G + + A D D G+N + Y++ + Sbjct: 1029 RTVSLNVSDVNDNAPAFFRRSHEVFVQENNRPGVLLCSLAASDPDSGLNGLIAYSLLEP- 1087 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 G +G V+ + D E Q V A D G+PP S+T T Sbjct: 1088 -RGR---------ETGAVHAARSFDYEQTQTLQFEVQARDRGEPPLSSTVT 1128 Score = 56.0 bits (129), Expect = 1e-05 Identities = 62/242 (25%), Positives = 96/242 (39%), Gaps = 27/242 (11%) Query: 342 GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHY 401 G PP S+ T F +EV + E+ PG + +L A+D D Sbjct: 1021 GSPPLSSQRTVSLNVSDVNDNAPAFFRRSHEVFVQENNRPGVLLCSLAASDPD------- 1073 Query: 402 EITGGNTRGRFSITSQNGR--GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQI 457 +G N +S+ GR G + A+ D++Q + V A D G S T V++ Sbjct: 1074 --SGLNGLIAYSLLEPRGRETGAVHAARSFDYEQTQTLQFEVQARDRGEPPLSSTVTVRL 1131 Query: 458 NITDANNYAPVF------ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE 511 I D N+ AP A ++ A G V V+A D D G NA ++Y L Sbjct: 1132 FILDVNDNAPAVLRPQARPGALCPQALPPSASAGHLVTKVTAVDLDSGYNAWVSYQLFE- 1190 Query: 512 ISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571 A F ++ G I T + + + L + +D G P LS + + +S+ Sbjct: 1191 ------APDPTLFAVSRYAGEIRTAGPIPAD-LPPQRLVIMVQDSGNPPLSTSVTLLVSL 1243 Query: 572 VD 573 D Sbjct: 1244 ED 1245 >UniRef50_UPI0000583D73 Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 1326 Score = 242 bits (592), Expect = 1e-61 Identities = 194/683 (28%), Positives = 311/683 (45%), Gaps = 42/683 (6%) Query: 92 IDGRSGALLTRASLDREKVAR-YTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQF 150 +D ++G L T LDRE++ + L + A + R T+ V I D ND+ P+F Sbjct: 72 LDSQTGELTTVLDLDREELCPGSSALCEIEVNAIELGTR--EVITVKVTINDINDHAPEF 129 Query: 151 SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS------AIRYAIIGGNTQMQFSIDS 204 + +S+ E SV A+D D+G N+ + YA G Q +F Sbjct: 130 RDDLTNMSIPE--SVVPGTRFPLSTASDEDIGENAIQGYRLSDEYAETFGLVQNEFPGGL 187 Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 + + ++ +LD E +Y + + A DGG P S T L + + D +D++P F + +Q Sbjct: 188 IIIQLEVIGSLDRENKDNYVMTLYADDGGDPVLSGVTTLNVTVLDSDDHSPVFDRTSYQV 247 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 SV+EN+ +G I++V+A D D G N ++ Y ++L ID SGW+ +L Sbjct: 248 SVAENIGVGQHIIQVRASDPDTGTNGQIIYDFGGSVSAKIIEL-FEIDSESGWLSVKSEL 306 Query: 325 DRETQAKYQLLVTATDG-GDP-PRSATATXXXXXXXXXXXXXXFMP----GQYEVELAED 378 D E ++ +Q+ + AT+ +P P T T G+++ +AE+ Sbjct: 307 DFEDESSHQVSIRATNNVPNPLPDFTTVTVNLIDVNDNKPRLTISALGDGGRFK-HIAEN 365 Query: 379 EPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITS-QNGRGLITVAQPLDFKQERRY 437 P V + TD D +T + G F + S + G+ + A LD + Y Sbjct: 366 SPEDVDVAYVRVTDMDTGVNGQAILTLEDDFGHFYLESFREGQYFLKTAGVLDREDIDFY 425 Query: 438 VLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495 +T+ A D G S + + D N+ +P+F ++ Y A++ E+ G V V A D Sbjct: 426 NITILAEDRGSPVLSSRRRFAVFVDDENDNSPIFSSSVYHATISENNEPGHRVATVQAID 485 Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555 D N ++ YSL + D F I+P G +T N LDRE L + A D Sbjct: 486 KDELENGEVVYSLLDD--------KDGSFGIHPFNGVLTANVSLDREDGESIDLMIRACD 537 Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615 G P + + V+D+NDN P F L I E+ GT V + ATDAD G NGR Sbjct: 538 RGQPQGCSDVPLTVRVLDMNDNGPTFGGDLIEMRIDENKPSGTIVGRAVATDADEGDNGR 597 Query: 616 IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675 + Y + + F ID SG I + LDRE + A+D G P+++T V + Sbjct: 598 LRYSI----LTDAVFRIDEDSGRIYSTAELDREIQELYHFTVRAVDDGLSPKTATATVVV 653 Query: 676 KIEDINDSPPVF---ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732 + D ND P F + +I ++ G I + + D D+ NA V Y+I G+ + Sbjct: 654 TVNDGNDHSPEFIVPSAKNDIRFIPVSADPGLHIMTVESEDEDKDENAAVSYAISHGNTN 713 Query: 733 NSFSLETRQGSDKAELVTMVDLD 755 +F ++ ++VT DL+ Sbjct: 714 GAFGIQA-----NGQVVTAQDLE 731 Score = 226 bits (552), Expect = 8e-57 Identities = 202/687 (29%), Positives = 302/687 (43%), Gaps = 59/687 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ + D NDH+P F S+ E GT A+D+DIG+NA Y + A+T Sbjct: 116 KVTINDINDHAPEFRDDLTNMSIPESVVPGTRFPLSTASDEDIGENAIQGYRLSDEYAET 175 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 VQ+ F L SLDRE Y + + A D PV Sbjct: 176 FG-------------LVQNEFPGGLIIIQLEVIGSLDRENKDNYVMTLYADDGGDPV--- 219 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LS T++V ++D +D+ P F +Y VSV E+I V + I +++A+D D G N I Y Sbjct: 220 LSGVTTLNVTVLDSDDHSPVFDRTSYQVSVAENIGVGQH--IIQVRASDPDTGTNGQIIY 277 Query: 190 AIIGGNTQMQ----FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 GG+ + F IDS SG +S+ LD+E S+++ IRA + + T + + Sbjct: 278 DF-GGSVSAKIIELFEIDSESGWLSVKSELDFEDESSHQVSIRATNNVPNPLPDFTTVTV 336 Query: 246 NIRDVNDNAPRFYTSLFQES-----VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 N+ DVNDN PR S + ++EN P + V+ D D GVN + T+ D D Sbjct: 337 NLIDVNDNKPRLTISALGDGGRFKHIAENSPEDVDVAYVRVTDMDTGVNGQAILTLED-D 395 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 + G+ L + ++ T+G LDRE Y + + A D G P S+ Sbjct: 396 F-GHFYLE-SFREGQYFLKTAGVLDREDIDFYNITILAEDRGSPVLSSRRRFAVFVDDEN 453 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQN 418 F Y ++E+ PG V T+ A D DE + + Y + G F I N Sbjct: 454 DNSPIFSSSVYHATISENNEPGHRVATVQAIDKDELENGEVVYSLLDDKD-GSFGIHPFN 512 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYT 475 G ++T LD + L + A D G G SD + + + D N+ P F Sbjct: 513 G--VLTANVSLDREDGESIDLMIRACDRGQPQGCSDVPLT-VRVLDMNDNGPTFGGDLIE 569 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 + E+ P GT V ATD+D G N ++ YS+ + D F I+ +G I + Sbjct: 570 MRIDENKPSGTIVGRAVATDADEGDNGRLRYSILT----------DAVFRIDEDSGRIYS 619 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF-----KQQLYTANI 590 LDRE Y TV A D G+ + T V ++V D ND+ P F K + + Sbjct: 620 TAELDREIQELYHFTVRAVDDGLSPKTATATVVVTVNDGNDHSPEFIVPSAKNDIRFIPV 679 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650 D G + V + D D N + Y + G+F I A+G + T + L+ Sbjct: 680 SADP--GLHIMTVESEDEDKDENAAVSYAIS-HGNTNGAFGIQ-ANGQVVTAQDLEPMWE 735 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKI 677 HD+ A DGG P SST ++ + I Sbjct: 736 GVHDITIRATDGGNPSASSTAVLRVVI 762 Score = 225 bits (550), Expect = 1e-56 Identities = 190/657 (28%), Positives = 295/657 (44%), Gaps = 47/657 (7%) Query: 160 DEDISVTDNPVIAKIKATDADVGANSAIRYAIIG-GNTQMQFSIDSLSGDVSLVKTLDYE 218 D D V VI + A D + ++ ++++G N S+DS +G+++ V LD E Sbjct: 30 DIDEGVGPGTVIGNV-ADDLAITIDANTEFSMLGVPNETAYVSLDSQTGELTTVLDLDRE 88 Query: 219 QV--RSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSI 276 ++ S L + + + I D+ND+AP F L S+ E+V G Sbjct: 89 ELCPGSSALCEIEVNAIELGTREVITVKVTINDINDHAPEFRDDLTNMSIPESVVPGTRF 148 Query: 277 VRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS----GQLDRETQAKY 332 A D D G NA Y ++D +Y L P G + G LDRE + Y Sbjct: 149 PLSTASDEDIGENAIQGYRLSD-EYAETFGLVQNEFP-GGLIIIQLEVIGSLDRENKDNY 206 Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392 + + A DGGDP S T F Y+V +AE+ G ++ + A+D Sbjct: 207 VMTLYADDGGDPVLSGVTTLNVTVLDSDDHSPVFDRTSYQVSVAENIGVGQHIIQVRASD 266 Query: 393 ADE--DNRLHYEITGGNTRGR----FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446 D + ++ Y+ GG+ + F I S++G ++V LDF+ E + +++ AT++ Sbjct: 267 PDTGTNGQIIYDF-GGSVSAKIIELFEIDSESG--WLSVKSELDFEDESSHQVSIRATNN 323 Query: 447 --GGRSDTAMVQINITDANNYAP-----VFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499 D V +N+ D N+ P + + E++P V V TD D G Sbjct: 324 VPNPLPDFTTVTVNLIDVNDNKPRLTISALGDGGRFKHIAENSPEDVDVAYVRVTDMDTG 383 Query: 500 INAQITYSLSSEISNEAV-AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558 +N Q +L + + + + + Q+ + T +LDRE + Y +T+ A D G Sbjct: 384 VNGQAILTLEDDFGHFYLESFREGQYFLK-------TAGVLDREDIDFYNITILAEDRGS 436 Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618 P LS + V D NDN P+F +Y A I E+ G V+ V A D D NG + Y Sbjct: 437 PVLSSRRRFAVFVDDENDNSPIFSSSVYHATISENNEPGHRVATVQAIDKDELENGEVVY 496 Query: 619 ELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678 L D ++GSF I P +GV+ N +LDRE + DL A D G P S V + +++ Sbjct: 497 SL--LDDKDGSFGIHPFNGVLTANVSLDREDGESIDLMIRACDRGQPQGCSDVPLTVRVL 554 Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738 D+ND+ P F D + I EN P GT +G A D DEG N + YSI F ++ Sbjct: 555 DMNDNGPTFGGDLIEMRIDENKPSGTIVGRAVATDADEGDNGRLRYSIL---TDAVFRID 611 Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAP 792 D + + +LD E ++ Y +RA P V + V D ND++P Sbjct: 612 ----EDSGRIYSTAELDREI-QELYHFTVRAVDDGLSPKTATATVVVTVNDGNDHSP 663 Score = 141 bits (342), Expect = 2e-31 Identities = 112/369 (30%), Positives = 174/369 (47%), Gaps = 24/369 (6%) Query: 439 LTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498 + V+A + G R + V++ I D N++AP F + S+ E GT + +A+D D+ Sbjct: 100 IEVNAIELGTR-EVITVKVTINDINDHAPEFRDDLTNMSIPESVVPGTRFPLSTASDEDI 158 Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558 G NA Y LS E + E +F + LDRE Y++T+ A DGG Sbjct: 159 GENAIQGYRLSDEYA-ETFGLVQNEFPGGLIIIQLEVIGSLDRENKDNYVMTLYADDGGD 217 Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618 P LS T + ++V+D +D+ PVF + Y ++ E+ VG + QV A+D D G NG+I Y Sbjct: 218 PVLSGVTTLNVTVLDSDDHSPVFDRTSYQVSVAENIGVGQHIIQVRASDPDTGTNGQIIY 277 Query: 619 ELDPKDREE--GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676 + + F ID SG + LD E ++H + A + P V + Sbjct: 278 DFGGSVSAKIIELFEIDSESGWLSVKSELDFEDESSHQVSIRATNNVPNPLPDFTTVTVN 337 Query: 677 IEDINDSPPVFESDCL----TF-YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD 731 + D+ND+ P L F +I+ENSP + +R D D G N +++ DD Sbjct: 338 LIDVNDNKPRLTISALGDGGRFKHIAENSPEDVDVAYVRVTDMDTGVNGQAILTLE--DD 395 Query: 732 SNSFSLET-RQGS---DKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILV 784 F LE+ R+G A ++ D+D+ Y + I A SP L + R + V Sbjct: 396 FGHFYLESFREGQYFLKTAGVLDREDIDF------YNITILAEDRGSPVLSSRRRFAVFV 449 Query: 785 TDVNDNAPV 793 D NDN+P+ Sbjct: 450 DDENDNSPI 458 >UniRef50_Q8TAB3 Cluster: Protocadherin-19 precursor; n=31; Euteleostomi|Rep: Protocadherin-19 precursor - Homo sapiens (Human) Length = 1148 Score = 241 bits (589), Expect = 3e-61 Identities = 175/543 (32%), Positives = 248/543 (45%), Gaps = 33/543 (6%) Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + I+D+NDNAP F + + +SE G I AYD D G TY +T + G Sbjct: 117 VEIKDLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFG- 175 Query: 305 VDLPITID-PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 +++ D R + LDRETQ+ Y +TA DGGDPPR T Sbjct: 176 LEIKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNN 235 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGG-NTRGRFSITSQNGR 420 F Y V + E+ PP TPV+ L A+D DE + ++ Y G N R R Sbjct: 236 PVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHS 295 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTAS- 477 GL+TV LD+++ Y L V A D G S A V +++ D N+ PV + Sbjct: 296 GLVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSEL 355 Query: 478 --VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 V E AP G + +V +D D G+N ++ L + N V Q++ I Sbjct: 356 VEVSESAPPGYVIALVRVSDRDSGLNGRVQCRL---LGN--VPFRLQEY---ESFSTILV 407 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 + LDRE Y LT+ ARDGGVP L + + D NDN P F + Y + E+ Sbjct: 408 DGRLDREQHDQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNT 467 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDP---KDREEGSFV-IDPASGVIRTNKALDRESVA 651 G + V A D D+GLNG + Y++ P +D ++V I+P SG I ++ + E Sbjct: 468 PGAYLLSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTK 527 Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL-----TFYISENSPIGTTI 706 + K +A DGG P S V + I D+ND+ PV + L YI NS IG + Sbjct: 528 AFEFKVLAKDGGLPSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLV 587 Query: 707 GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV 766 ++A D DEG N V Y + G D F ++ G V ES + YEL+ Sbjct: 588 TVVKAEDYDEGENGRVTYDMTEG-DRGFFEIDQVNGE-----VRTTRTFGESSKSSYELI 641 Query: 767 IRA 769 + A Sbjct: 642 VVA 644 Score = 212 bits (518), Expect = 1e-52 Identities = 181/609 (29%), Positives = 268/609 (44%), Gaps = 31/609 (5%) Query: 92 IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151 I+ SG L+T+ +DR+ + R + K +S + I V I D NDN P F Sbjct: 74 INPSSGLLVTKQKIDRDLLCRQSP--KCIISLEVMSSSME-ICVIKVEIKDLNDNAPSFP 130 Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNT---QMQFSID-SLSG 207 + + E + + I A D D G+ Y + +++ D S Sbjct: 131 AAQIELEISE--AASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSRFA 188 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 ++ + K+LD E Y I A DGG P R T L I + D NDN P F S + SV Sbjct: 189 ELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYAVSVP 248 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 EN P ++R+ A D DEG N ++ Y+ +L IDP SG V +G LD E Sbjct: 249 ENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTREL-FQIDPHSGLVTVTGALDYE 307 Query: 328 TQAKYQLLVTATDGG--DPPRSATATXXXXXXXXXXXXXXFMPGQYE-VELAEDEPPGTP 384 Y+L V A D G P T + E VE++E PPG Sbjct: 308 EGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYV 367 Query: 385 VVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 + + +D D + R+ + G F + I V LD +Q +Y LT+ Sbjct: 368 IALVRVSDRDSGLNGRVQCRLLGNVP---FRLQEYESFSTILVDGRLDREQHDQYNLTIQ 424 Query: 443 ATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 A D G + ITD N+ P F Y V E+ G +L VSA D D+G+ Sbjct: 425 ARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGL 484 Query: 501 NAQITYSL-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 N ++Y + S++ + V + INP +G I + + E + V A+DGG+P Sbjct: 485 NGSVSYQIVPSQVRDMPVFTY---VSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLP 541 Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLY---TAN--IMEDALVGTSVSQVGATDADVGLNG 614 SL V + ++DVNDN PV TA I ++ +G V+ V A D D G NG Sbjct: 542 SLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGENG 601 Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674 R+ Y++ DR G F ID +G +RT + S ++++L VA D G S++ +V Sbjct: 602 RVTYDMTEGDR--GFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVL 659 Query: 675 IKIEDINDS 683 I + D+ Sbjct: 660 IYLSPALDA 668 Score = 164 bits (399), Expect = 3e-38 Identities = 130/443 (29%), Positives = 200/443 (45%), Gaps = 22/443 (4%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGL- 422 F Q E+E++E PGT + +A D D + YE+T G T +G Sbjct: 129 FPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSRFA 188 Query: 423 -ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVF 479 + V + LD + + Y ++A D G R T + I +TD+N+ PVF + Y SV Sbjct: 189 ELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYAVSVP 248 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E++P T V+ ++A+D D G N Q+ YS +++ + F I+P +G +T L Sbjct: 249 ENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRT----RELFQIDPHSGLVTVTGAL 304 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME---DALV 596 D E Y L V A+D G S+ V +SV+D NDN PV + ++E A Sbjct: 305 DYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPP 364 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 G ++ V +D D GLNGR+ L + I + LDRE ++L Sbjct: 365 GYVIALVRVSDRDSGLNGRVQCRL--LGNVPFRLQEYESFSTILVDGRLDREQHDQYNLT 422 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 A DGG P S + I D ND+ P F + EN+ G + + A DPD Sbjct: 423 IQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDL 482 Query: 717 GPNAVVHYSIKGGD--DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--- 771 G N V Y I D F+ + + ++ + ++E K +E + A Sbjct: 483 GLNGSVSYQIVPSQVRDMPVFTYVSIN-PNSGDIYALRSFNHEQT-KAFEFKVLAKDGGL 540 Query: 772 PPLWNDVRVEILVTDVNDNAPVM 794 P L ++ V +++ DVNDN PV+ Sbjct: 541 PSLQSNATVRVIILDVNDNTPVI 563 Score = 147 bits (357), Expect = 3e-33 Identities = 133/465 (28%), Positives = 201/465 (43%), Gaps = 38/465 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND++PVF Y SV E + T V+ L A+D D G N +V Y+ D Sbjct: 226 IKVTDSNDNNPVFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDR- 284 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +++F+ID SG + +LD E+ Y + V+A D P S + Sbjct: 285 ---------------TRELFQIDPHSGLVTVTGALDYEEGHVYELDVQAKD-LGPNS--I 326 Query: 131 SSTATIHVNIIDDNDNYP---QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 + + V+++D NDN P S + V V E S VIA ++ +D D G N + Sbjct: 327 PAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSE--SAPPGYVIALVRVSDRDSGLNGRV 384 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 + ++ GN + + + LD EQ Y L I+A+DGG P + + I Sbjct: 385 QCRLL-GNVPFRLQEYESFSTILVDGRLDREQHDQYNLTIQARDGGVPMLQSAKSFTVLI 443 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NVD 306 D NDN P F +Q V EN G ++ V A D D G+N ++Y + V Sbjct: 444 TDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLNGSVSYQIVPSQVRDMPVF 503 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT-----XXXXXXXXXX 361 ++I+P SG +Y + E ++ V A DGG P + AT Sbjct: 504 TYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQSNATVRVIILDVNDNTPVI 563 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419 + G EV + + G V + A D D E+ R+ Y++T G+ RG F I NG Sbjct: 564 TAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRVTYDMTEGD-RGFFEIDQVNG 622 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDA 462 + + + Y L V A D G S +A+V I ++ A Sbjct: 623 E--VRTTRTFGESSKSSYELIVVAHDHGKTSLSASALVLIYLSPA 665 Score = 123 bits (297), Expect = 6e-26 Identities = 119/432 (27%), Positives = 188/432 (43%), Gaps = 31/432 (7%) Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 SV E+ GT + V+ + G + + + + + H INP +G + T Sbjct: 28 SVEEEQRAGTVIANVAKDAREAGFALDPRQASAFRVVSNSAPHLVD---INPSSGLLVTK 84 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 + +DR+ + + S + +++ + D+NDN P F I E A Sbjct: 85 QKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKDLNDNAPSFPAAQIELEISEAASP 144 Query: 597 GTSVSQVGATDADVGLNGRIHYELDP--------KDREEGSFVIDPASGVIRTNKALDRE 648 GT + A D D G G YEL P K R +GS + + K+LDRE Sbjct: 145 GTRIPLDSAYDPDSGSFGVQTYELTPNELFGLEIKTRGDGSRFAE-----LVVEKSLDRE 199 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 + + + + A+DGG PP+ TV + IK+ D ND+ PVF + ENSP T + Sbjct: 200 TQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPVFSESTYAVSVPENSPPNTPVIR 259 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVI 767 + A DPDEG N V YS G N + E Q + LVT+ LDYE YEL + Sbjct: 260 LNASDPDEGTNGQVVYSFYG--YVNDRTRELFQIDPHSGLVTVTGALDYEEGH-VYELDV 316 Query: 768 RA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN--NYKDCFPVG---PFGRVPAY 819 +A + +V + V D NDN PV+ + + P G RV Sbjct: 317 QAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYVIALVRVSDR 376 Query: 820 DADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKA 878 D+ + ++Q R+L GN + E+ ++ + +L+ + + D GV +++ Sbjct: 377 DSGLNGRVQCRLL-GNVPFRLQEYESFSTILVDGRLDREQHDQYNLTIQARDGGVPMLQS 435 Query: 879 MMQLSVRLITEE 890 +V LIT+E Sbjct: 436 AKSFTV-LITDE 446 >UniRef50_Q5CCS6 Cluster: Af1-cadherin; n=1; Artemia franciscana|Rep: Af1-cadherin - Artemia sanfranciscana (Brine shrimp) (Artemia franciscana) Length = 1566 Score = 239 bits (586), Expect = 6e-61 Identities = 192/665 (28%), Positives = 318/665 (47%), Gaps = 51/665 (7%) Query: 171 IAKIKATDADVGANSAIRYAIIGGNT-QMQFSIDSLSGDVSLVKTLDYEQVRSYRLV--- 226 + K++A D D G +RY II + + QF+++S +G+++ K D ++ + +L+ Sbjct: 131 VTKVEAYDPDQGPAGKVRYEIIRSQSAEKQFNVNSYTGEITTAKVFDRDEPKREKLLYVT 190 Query: 227 IRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE 286 ++A D G P+ + I D NDNAP F + ++E++ ++ + +++RV A D DE Sbjct: 191 VKAVDEGFPALDVLCTFSVTITDKNDNAPIFDKNDYRETIPQDSKVNQTVMRVAATDIDE 250 Query: 287 GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE-TQAKYQLLVTATDGGDPP 345 G NA +TY++ ++D IDP+SG++ ++ E +++L+ A DGG P Sbjct: 251 GENARITYSLRANRDESDLDY-FQIDPQSGFIKLVKAIEAEKVDYQFELVAAARDGGTPS 309 Query: 346 RSATATXXXXXXXXXXXXXXFMP-GQYEVELAED-EPPGTPVVTLTATDADEDNRLHYEI 403 TA F + +++ E G P+VTL A E +++ + Sbjct: 310 NETTAQVNIKVVSSNRRAPEFTEVPDHIIDIEESFNDFGRPIVTLRAVSNIEKPVVYFSL 369 Query: 404 TGGNTRGR-----FSITSQ-NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQI 457 G T F + + NG I +A+ LD++ Y L + + S +V++ Sbjct: 370 VNGQTEDTNKEETFRLVERANGTMDIFLARKLDYETVSNYQLNIRVQNDFDVSAETIVRL 429 Query: 458 NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEA 516 + D+N+ P F + + SV E++ + T VL + A D D N ++TY L S Sbjct: 430 RVLDSNDEIPSFIDIE-SGSVLENSAVQTFVLRIRAIDKDGTSPNNKVTYRLLSNTDT-- 486 Query: 517 VAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL-SD------TTDVEI 569 F I+ +TG I T K LDRE S Y +TV A+DG SL SD ++ Sbjct: 487 -------FSIDSETGEIRTLKRLDREETSSYAVTVQAQDGAPSSLRSDGLPNMYQKKFKV 539 Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629 V+D NDN P F+Q Y A I EDA + + V +V A D D I Y++ + + + Sbjct: 540 EVLDQNDNPPRFEQPTYNAEIAEDADINSKVIEVTARDKDDF--AVIRYDITDGN-VDNA 596 Query: 630 FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES 689 F+++ SGVIR N LD E + + L+ A DG S VH+ I ++ND+PP+FE+ Sbjct: 597 FMVEEKSGVIRVNNQLDYEKITDYYLRVRASDG---IHSDEATVHVSISNVNDNPPIFEN 653 Query: 690 ---DCLTFYISENSPIGTTIGEIRAHDPD---EGPNAVVHYSI-KGGDDSNSFSLETRQG 742 + I E I +I DPD G N + +S+ + G + F + T +G Sbjct: 654 MQNPHVVRNIIEEEKRPDPIAKITVRDPDWDKGGKNPYITFSLDRTGQYAKHFRI-TPEG 712 Query: 743 SDKAELVTMVDLDYESPRKKYELVIRAASPPLW----NDVRVEILVTDVNDNAPVMKDFQ 798 + D P+ + ++ P N + VEI + D+NDNAP + Q Sbjct: 713 ELFLDKGIDRDPPNGYPQARVNIIAEDRLEPNGKVQSNTLVVEIHLDDINDNAPFLNMEQ 772 Query: 799 -IIFN 802 ++FN Sbjct: 773 PVVFN 777 Score = 234 bits (573), Expect = 2e-59 Identities = 314/1247 (25%), Positives = 508/1247 (40%), Gaps = 138/1247 (11%) Query: 29 EASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQD 88 E S+ EG ++GT V ++A D D G +V Y E++ + + + Sbjct: 118 ETSIPEGENAGTFVTKVEAYDPDQGPAGKVRY--EIIRSQSAEKQ--------------- 160 Query: 89 VFRIDGRSGALLTRASLDREKVARYTVL---VKATDQASPVSDRLSSTATIHVNIIDDND 145 F ++ +G + T DR++ R +L VKA D+ P D L T V I D ND Sbjct: 161 -FNVNSYTGEITTAKVFDRDEPKREKLLYVTVKAVDEGFPALDVL---CTFSVTITDKND 216 Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ---FSI 202 N P F + Y ++ +D V N + ++ ATD D G N+ I Y++ + F I Sbjct: 217 NAPIFDKNDYRETIPQDSKV--NQTVMRVAATDIDEGENARITYSLRANRDESDLDYFQI 274 Query: 203 DSLSGDVSLVKTLDYEQV-RSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261 D SG + LVK ++ E+V + LV A+DGG+PS T Q+ I + N AP F T + Sbjct: 275 DPQSGFIKLVKAIEAEKVDYQFELVAAARDGGTPSNETTAQVNIKVVSSNRRAPEF-TEV 333 Query: 262 FQE--SVSENV-PIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW- 317 + E+ G IV ++A E + + T + ++ +G Sbjct: 334 PDHIIDIEESFNDFGRPIVTLRAVSNIEKPVVYFSLVNGQTEDTNKEETFRLVERANGTM 393 Query: 318 -VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376 ++ + +LD ET + YQL + + D SA F+ + + Sbjct: 394 DIFLARKLDYETVSNYQLNIRVQNDFDV--SAETIVRLRVLDSNDEIPSFIDIE-SGSVL 450 Query: 377 EDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ 433 E+ T V+ + A D D +N++ Y + NT FSI S+ G I + LD ++ Sbjct: 451 ENSAVQTFVLRIRAIDKDGTSPNNKVTYRLL-SNT-DTFSIDSETGE--IRTLKRLDREE 506 Query: 434 ERRYVLTVSATD---SGGRSD------TAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 Y +TV A D S RSD ++ + D N+ P FE Y A + EDA I Sbjct: 507 TSSYAVTVQAQDGAPSSLRSDGLPNMYQKKFKVEVLDQNDNPPRFEQPTYNAEIAEDADI 566 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 + V+ V+A D D A I Y ++ + D F++ ++G I N LD E + Sbjct: 567 NSKVIEVTARDKD--DFAVIRYDITD-------GNVDNAFMVEEKSGVIRVNNQLDYEKI 617 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL---YTANIMEDALVGTSVS 601 + Y L V A DG SD V +S+ +VNDN P+F+ NI+E+ ++ Sbjct: 618 TDYYLRVRASDG---IHSDEATVHVSISNVNDNPPIFENMQNPHVVRNIIEEEKRPDPIA 674 Query: 602 QVGATDAD---VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD---L 655 ++ D D G N I + LD + F I P G + +K +DR+ + + Sbjct: 675 KITVRDPDWDKGGKNPYITFSLDRTGQYAKHFRITP-EGELFLDKGIDRDPPNGYPQARV 733 Query: 656 KAVAIDGGTP---PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 +A D P QS+T++V I ++DIND+ P + + P+ I + A Sbjct: 734 NIIAEDRLEPNGKVQSNTLVVEIHLDDINDNAPFLNMEQPVVFNENQKPM--LITNLTAD 791 Query: 713 DPDE---GPNAVVHYSIKGGDDS---NSFSLETRQGSDKAELVTMVDLDYESPRKKYELV 766 D D+ G I + SF++ + S +L + V D E RK Y + Sbjct: 792 DNDDESVGNGPPFQMRIDPNAEPIILTSFAV-NKAPSGVWQLHSNVMFDREE-RKVYNIP 849 Query: 767 I----RAASPPLWNDV---RVEILVTDVNDNAPVMKDFQ--IIFNNYKDCFPVGPFGRVP 817 I P +E+++ D NDN MKD + I NYK+ P GR Sbjct: 850 IVISDNGGGDPSRRQTGTSTLEVVIGDENDND--MKDGKSAITVYNYKNSLPDTMIGRAY 907 Query: 818 AYDADVTDKLQYRILSGNNANLILLN-ETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEI 876 D D D + + G +T+ +L + V D Sbjct: 908 VDDPDDWDLPDKEFTWFDTIQPTYFSLHPKGMITMKAGTPAGEYRL---RIKVYDQKWNS 964 Query: 877 KAMMQLSVRL--ITEEMLLNSITVRLNDMTAEQFLSPLLG-----FFIDGLAAIIPCPKE 929 +A ++ V I EE + S +VRL+ +T F++P G D +A + P Sbjct: 965 QATAEVIVNSIEIPEEAVKKSGSVRLDGVTEVDFITPRGGESMREMLRDAVAKYLSVPLG 1024 Query: 930 NIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARL 989 N+ +F+V+ V I++ FS SP++ P + + T L Sbjct: 1025 NVDLFTVR---GVNKTIVDARFSVHN-----------SPYWDPVKINGLLGEKSTELKDT 1070 Query: 990 ATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEG 1049 ++L + C+ EP C + L + F+ ++ F + + C C G Sbjct: 1071 LKAEILGIGIDECMKEPGPCDGPCTSFLTILDTPYFIYGNTSSFVGVNAYADYDCACRIG 1130 Query: 1050 FTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCELRARS 1109 +N + CE C +G C+ L C + CE S Sbjct: 1131 -PVLNSPRGPIRDQCE-----EYCFNGGTCILNG----LFPRCECPDNFEGPRCEALEAS 1180 Query: 1110 FPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERHDFLALELVSSEAGRGGG 1169 F SF P L + +F + T +GL+ YNG ++ D + V+ E G Sbjct: 1181 FNGVSFGWLPSLPACSDGSITFEFTSHTENGLMFYNGPHSIPSDKSITDFVAVELD-DGI 1239 Query: 1170 PGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNR-TITMILDDC 1215 P + G K ++ N GD H +E+ + +R + + LD C Sbjct: 1240 PVAYINLGSGIRKLQLNDNKNYGDKESHLLELRWNDRQEVRLTLDGC 1286 Score = 210 bits (513), Expect = 4e-52 Identities = 195/746 (26%), Positives = 342/746 (45%), Gaps = 81/746 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND++P+F+ Y ++ + + TV+ + ATD D G+NA + Y++ Sbjct: 209 VTITDKNDNAPIFDKNDYRETIPQDSKVNQTVMRVAATDIDEGENARITYSLR------A 262 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKV-ARYTVLVKATDQASPVSDR 129 N +++ D F+ID +SG + +++ EKV ++ ++ A D +P ++ Sbjct: 263 NRDESDL----------DYFQIDPQSGFIKLVKAIEAEKVDYQFELVAAARDGGTPSNE- 311 Query: 130 LSSTATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 +TA +++ ++ N P+F+E + + ++E + P++ ++ + + Sbjct: 312 --TTAQVNIKVVSSNRRAPEFTEVPDHIIDIEESFNDFGRPIVTLRAVSNIE---KPVVY 366 Query: 189 YAIIGGNTQMQFS------IDSLSG--DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240 ++++ G T+ ++ +G D+ L + LDYE V +Y+L IR Q+ S Sbjct: 367 FSLVNGQTEDTNKEETFRLVERANGTMDIFLARKLDYETVSNYQLNIRVQNDFDVSAETI 426 Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDK 299 +L + D ND P F + SV EN + ++R++A D D N ++TY + Sbjct: 427 VRL--RVLDSNDEIPSF-IDIESGSVLENSAVQTFVLRIRAIDKDGTSPNNKVTYRL--- 480 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-------PRSATATX 352 N D +ID +G + T +LDRE + Y + V A DG P Sbjct: 481 --LSNTD-TFSIDSETGEIRTLKRLDREETSSYAVTVQAQDGAPSSLRSDGLPNMYQKKF 537 Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRF 412 F Y E+AED + V+ +TA D D+ + Y+IT GN F Sbjct: 538 KVEVLDQNDNPPRFEQPTYNAEIAEDADINSKVIEVTARDKDDFAVIRYDITDGNVDNAF 597 Query: 413 SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENA 472 + ++ G+I V LD+++ Y L V A+D G SD A V ++I++ N+ P+FEN Sbjct: 598 MVEEKS--GVIRVNNQLDYEKITDYYLRVRASD-GIHSDEATVHVSISNVNDNPPIFENM 654 Query: 473 --PYTA-SVFEDAPIGTTVLVVSATDSD---VGINAQITYSLSSEISNEAVAHHDQQFVI 526 P+ ++ E+ + ++ D D G N IT+SL + + + F I Sbjct: 655 QNPHVVRNIIEEEKRPDPIAKITVRDPDWDKGGKNPYITFSL------DRTGQYAKHFRI 708 Query: 527 NPQTGAITTNKLLDRETMSGY---LLTVTARDGGVPS---LSDTTDVEISVVDVNDNEPV 580 P+ G + +K +DR+ +GY + + A D P+ S+T VEI + D+NDN P Sbjct: 709 TPE-GELFLDKGIDRDPPNGYPQARVNIIAEDRLEPNGKVQSNTLVVEIHLDDINDNAPF 767 Query: 581 FK-QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE--EGSFVIDPA-S 636 +Q N + ++ T+++ D VG +DP SF ++ A S Sbjct: 768 LNMEQPVVFNENQKPMLITNLTADDNDDESVGNGPPFQMRIDPNAEPIILTSFAVNKAPS 827 Query: 637 GV--IRTNKALDRESVATHDLKAVAID--GGTPP--QSSTVIVHIKIEDINDSPPVFESD 690 GV + +N DRE +++ V D GG P Q+ T + + I D ND+ Sbjct: 828 GVWQLHSNVMFDREERKVYNIPIVISDNGGGDPSRRQTGTSTLEVVIGDENDNDMKDGKS 887 Query: 691 CLTFYISENSPIGTTIGEIRAHDPDE 716 +T Y +NS T IG DPD+ Sbjct: 888 AITVYNYKNSLPDTMIGRAYVDDPDD 913 Score = 143 bits (346), Expect = 7e-32 Identities = 149/499 (29%), Positives = 222/499 (44%), Gaps = 43/499 (8%) Query: 398 RLHYEITGGNTRGRFS---ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM 454 R H+E+ +F + Q GR ++ P Q+++ V + S + Sbjct: 40 RSHFEVESIGEHLKFEKHHVRRQAGRQPYRLSDPQ--LQKQKMVNSESPEARAASMPSRG 97 Query: 455 VQINITDAN-NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513 V N T A N P F T S+ E GT V V A D D G ++ Y + S Sbjct: 98 VTPNPTAAAINTRPTFIKCNET-SIPEGENAGTFVTKVEAYDPDQGPAGKVRYEIIRSQS 156 Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL---TVTARDGGVPSLSDTTDVEIS 570 E +QF +N TG ITT K+ DR+ L TV A D G P+L ++ Sbjct: 157 AE------KQFNVNSYTGEITTAKVFDRDEPKREKLLYVTVKAVDEGFPALDVLCTFSVT 210 Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS- 629 + D NDN P+F + Y I +D+ V +V +V ATD D G N RI Y L +R+E Sbjct: 211 ITDKNDNAPIFDKNDYRETIPQDSKVNQTVMRVAATDIDEGENARITYSL-RANRDESDL 269 Query: 630 --FVIDPASGVIRTNKALDRESV-ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686 F IDP SG I+ KA++ E V +L A A DGGTP +T V+IK+ N P Sbjct: 270 DYFQIDPQSGFIKLVKAIEAEKVDYQFELVAAARDGGTPSNETTAQVNIKVVSSNRRAPE 329 Query: 687 FES--DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD 744 F D + + G I +RA E P VV++S+ G ++ ET + + Sbjct: 330 FTEVPDHIIDIEESFNDFGRPIVTLRAVSNIEKP--VVYFSLVNGQTEDTNKEETFRLVE 387 Query: 745 KA----ELVTMVDLDYESPRKKYELVIRAASP-PLWNDVRVEILVTDVNDNAPVMKDFQ- 798 +A ++ LDYE+ Y+L IR + + + V + V D ND P D + Sbjct: 388 RANGTMDIFLARKLDYETV-SNYQLNIRVQNDFDVSAETIVRLRVLDSNDEIPSFIDIES 446 Query: 799 --IIFNNYKDCFPVGPFGRVPAYDADVT---DKLQYRILSGNNANLILLNETTGSMTLSP 853 ++ N+ F + R+ A D D T +K+ YR+LS N + ++ TG + Sbjct: 447 GSVLENSAVQTFVL----RIRAIDKDGTSPNNKVTYRLLS--NTDTFSIDSETGEIRTLK 500 Query: 854 QLNTNVPKLATMEVSVTDG 872 +L+ + V DG Sbjct: 501 RLDREETSSYAVTVQAQDG 519 >UniRef50_UPI00006A1011 Cluster: FAT tumor suppressor homolog 3; n=1; Xenopus tropicalis|Rep: FAT tumor suppressor homolog 3 - Xenopus tropicalis Length = 978 Score = 239 bits (584), Expect = 1e-60 Identities = 175/533 (32%), Positives = 262/533 (49%), Gaps = 27/533 (5%) Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYA 466 G F++ +G +I + QPLD + + Y +TV A+D S A V I + D N+ Sbjct: 17 GHFAVDMSSG--IIILEQPLDRELQSSYNITVKASDLSPVLTLSSLAFVTITVLDVNDNP 74 Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 P+FE Y +V ED +GT VL V A D+G NA+I YS+ S NE QF I Sbjct: 75 PIFERRDYWVTVAEDTTLGTKVLSVFAASKDIGTNAEILYSIRS--GNEHA-----QFFI 127 Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586 NP+TGAI+ LD E + L V A DGG PSLS T V I++ DVNDN PVF Q++Y Sbjct: 128 NPKTGAISVVNTLDYENCKHFYLVVEATDGGSPSLSAVTTVNINLTDVNDNAPVFSQEVY 187 Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646 +A I EDA VG SV V T + NG ++ + PA G R A Sbjct: 188 SAVISEDASVGDSVVMVSVTSSI--SNGLFYFAAN--FNHFFLLFTTPAEG--RQRGASA 241 Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706 R V+ + L A D G P SSTV V+I I D+ND+ P F + I EN P+GT+I Sbjct: 242 RWKVSGYSLLVQARDSGAPALSSTVTVNIDISDVNDNSPQFTPANYSAVIQENKPVGTSI 301 Query: 707 GEIRAHDPDEGPNA-VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765 ++ D D N ++I G++ F L+ + G ++ +V + E Sbjct: 302 VQLVVTDKDSFHNGPPFEFTIISGNEGGEFLLD-QSGVLRSAVVFQHTISDE--HLLCVQ 358 Query: 766 VIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD 825 V + P L + + I V + + + P ++ +D FP G G++ A D D+ D Sbjct: 359 VKDSGKPALTSQSFLHIRVIEESVHKPSAIPLEVYIVTMEDDFPGGVIGKIHATDQDIYD 418 Query: 826 KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVR 885 L Y L +L +N G + L+ T+ VSV DG ++ + + V Sbjct: 419 VLSYN-LKSEQKSLFKVNNHDGKLIALGGLDGG---KYTLNVSVNDGRYQVSIDVTVHVE 474 Query: 886 LITEEMLLNSITVRLNDMTAEQFLS-PLLGFFIDGLAAIIPCPKENIYIFSVQ 937 + +EML N++T+R +++ E F+ + GF A++ ++++YI S+Q Sbjct: 475 QLRQEMLQNAVTIRFENISPEDFVGLHMHGFRRTLRNAVLTQKEDSLYIISIQ 527 Score = 186 bits (453), Expect = 8e-45 Identities = 138/443 (31%), Positives = 209/443 (47%), Gaps = 26/443 (5%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F +D SG ++ LDRE + Y + VKA+D SPV LSS A + + ++D NDN P Sbjct: 19 FAVDMSSGIIILEQPLDRELQSSYNITVKASD-LSPVLT-LSSLAFVTITVLDVNDNPPI 76 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209 F + Y V+V ED ++ + + A D+G N+ I Y+I GN QF I+ +G + Sbjct: 77 FERRDYWVTVAEDTTLGTK--VLSVFAASKDIGTNAEILYSIRSGNEHAQFFINPKTGAI 134 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269 S+V TLDYE + + LV+ A DGGSPS S T + IN+ DVNDNAP F ++ +SE+ Sbjct: 135 SVVNTLDYENCKHFYLVVEATDGGSPSLSAVTTVNINLTDVNDNAPVFSQEVYSAVISED 194 Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329 +G S+V V ++ L Y + ++ + P G G R Sbjct: 195 ASVGDSVVMV---SVTSSISNGLFYFAANFNHF----FLLFTTPAEG--RQRGASARWKV 245 Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389 + Y LLV A D G P S+T T F P Y + E++P GT +V L Sbjct: 246 SGYSLLVQARDSGAPALSSTVTVNIDISDVNDNSPQFTPANYSAVIQENKPVGTSIVQLV 305 Query: 390 ATDADEDNR---LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446 TD D + + I GN G F + G++ A ++L V DS Sbjct: 306 VTDKDSFHNGPPFEFTIISGNEGGEFLLDQS---GVLRSAVVFQHTISDEHLLCVQVKDS 362 Query: 447 G--GRSDTAMVQINITDANNYAP-VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503 G + + + I + + + + P Y ++ +D P G + + ATD D I Sbjct: 363 GKPALTSQSFLHIRVIEESVHKPSAIPLEVYIVTMEDDFP-GGVIGKIHATDQD--IYDV 419 Query: 504 ITYSLSSE-ISNEAVAHHDQQFV 525 ++Y+L SE S V +HD + + Sbjct: 420 LSYNLKSEQKSLFKVNNHDGKLI 442 Score = 153 bits (372), Expect = 5e-35 Identities = 136/500 (27%), Positives = 227/500 (45%), Gaps = 32/500 (6%) Query: 182 GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP--SRSN 239 G N + Y+++ + F++D SG + L + LD E SY + ++A D SP + S+ Sbjct: 2 GINRKVVYSLVD-SADGHFAVDMSSGIIILEQPLDRELQSSYNITVKASDL-SPVLTLSS 59 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 + I + DVNDN P F + +V+E+ +G ++ V A D G NAE+ Y++ Sbjct: 60 LAFVTITVLDVNDNPPIFERRDYWVTVAEDTTLGTKVLSVFAASKDIGTNAEILYSIR-- 117 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 +GN I+P++G + LD E + L+V ATDGG P SA T Sbjct: 118 --SGNEHAQFFINPKTGAISVVNTLDYENCKHFYLVVEATDGGSPSLSAVTTVNINLTDV 175 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG 419 F Y ++ED G VV ++ T + N L Y N T G Sbjct: 176 NDNAPVFSQEVYSAVISEDASVGDSVVMVSVT-SSISNGLFYFAANFNHFFLLFTTPAEG 234 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477 R A+ + Y L V A DSG S T V I+I+D N+ +P F A Y+A Sbjct: 235 RQRGASAR----WKVSGYSLLVQARDSGAPALSSTVTVNIDISDVNDNSPQFTPANYSAV 290 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 + E+ P+GT+++ + TD D N + + NE +F+++ Q+G + + Sbjct: 291 IQENKPVGTSIVQLVVTDKDSFHNGP-PFEFTIISGNEG-----GEFLLD-QSGVLRSAV 343 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP-VFKQQLYTANIMEDALV 596 + +LL V +D G P+L+ + + I V++ + ++P ++Y MED Sbjct: 344 VFQHTISDEHLLCVQVKDSGKPALTSQSFLHIRVIEESVHKPSAIPLEVYIVT-MEDDFP 402 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 G + ++ ATD D+ + Y L K ++ F ++ G + LD + Sbjct: 403 GGVIGKIHATDQDI--YDVLSYNL--KSEQKSLFKVNNHDGKLIALGGLDGGKYTLN--- 455 Query: 657 AVAIDGGTPPQSSTVIVHIK 676 V+++ G S V VH++ Sbjct: 456 -VSVNDGRYQVSIDVTVHVE 474 Score = 147 bits (357), Expect = 3e-33 Identities = 123/436 (28%), Positives = 207/436 (47%), Gaps = 41/436 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I VLD ND+ P+FE + Y +V E + GT VL++ A +DIG NAE+ Y+I Sbjct: 65 ITVLDVNDNPPIFERRDYWVTVAEDTTLGTKVLSVFAASKDIGTNAEILYSIR------S 118 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 E A F I+ ++GA+ +LD E + ++V+ATD SP L Sbjct: 119 GNEHAQ-------------FFINPKTGAISVVNTLDYENCKHFYLVVEATDGGSP---SL 162 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+ T+++N+ D NDN P FS++ Y+ + ED SV D+ V+ + ++ +N +A Sbjct: 163 SAVTTVNINLTDVNDNAPVFSQEVYSAVISEDASVGDSVVMVSVTSSI----SNGLFYFA 218 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 N F + + + +V Y L+++A+D G+P+ S+T + I+I DV Sbjct: 219 ---ANFNHFFLLFTTPAEGRQRGASARWKVSGYSLLVQARDSGAPALSSTVTVNIDISDV 275 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA-ELTYTMTDKDYTGNVDLPI 309 NDN+P+F + + + EN P+G SIV++ D D N +T+ +GN Sbjct: 276 NDNSPQFTPANYSAVIQENKPVGTSIVQLVVTDKDSFHNGPPFEFTI----ISGNEGGEF 331 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 +D +SG + ++ ++ L V D G P ++ + +P Sbjct: 332 LLD-QSGVLRSAVVFQHTISDEHLLCVQVKDSGKPALTSQSFLHIRVIEESVHKPSAIPL 390 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 + + ED+ PG + + ATD D + L Y + + F + + +G+ LI + L Sbjct: 391 EVYIVTMEDDFPGGVIGKIHATDQDIYDVLSYNLK-SEQKSLFKVNNHDGK-LIALG-GL 447 Query: 430 DFKQERRYVLTVSATD 445 D +Y L VS D Sbjct: 448 D---GGKYTLNVSVND 460 Score = 70.9 bits (166), Expect = 5e-10 Identities = 64/242 (26%), Positives = 115/242 (47%), Gaps = 19/242 (7%) Query: 102 RASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE 161 R + R KV+ Y++LV+A D +P LSST T++++I D NDN PQF+ Y+ + E Sbjct: 237 RGASARWKVSGYSLLVQARDSGAPA---LSSTVTVNIDISDVNDNSPQFTPANYSAVIQE 293 Query: 162 DISVTDNPVIAKIKATDADVGANS-AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV 220 + V + I ++ TD D N + II GN +F +D SG + + Sbjct: 294 NKPVGTS--IVQLVVTDKDSFHNGPPFEFTIISGNEGGEFLLDQ-SGVLRSAVVFQHTIS 350 Query: 221 RSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP-RFYTSLFQESVSENVPIGYSIVRV 279 + L ++ +D G P+ ++ + L I + + + + P ++ ++ ++ P G I ++ Sbjct: 351 DEHLLCVQVKDSGKPALTSQSFLHIRVIEESVHKPSAIPLEVYIVTMEDDFP-GGVIGKI 409 Query: 280 QAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTAT 339 A D D + L+Y + + + ++ G + G LD KY L V+ Sbjct: 410 HATDQD--IYDVLSYNLKSEQKS-----LFKVNNHDGKLIALGGLD---GGKYTLNVSVN 459 Query: 340 DG 341 DG Sbjct: 460 DG 461 Score = 39.1 bits (87), Expect = 1.7 Identities = 12/39 (30%), Positives = 21/39 (53%) Query: 1310 CPEKRSRCSSAPCYNGAECSDLWDTYICDCKEGHTGKDC 1348 C E + C C NG C +++ ++ C+C G+ G+ C Sbjct: 754 CEEDINECEREDCENGGTCVNVFGSFFCNCSHGYVGQYC 792 >UniRef50_Q4RKB4 Cluster: Chromosome 18 SCAF15030, whole genome shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 18 SCAF15030, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1521 Score = 239 bits (584), Expect = 1e-60 Identities = 194/623 (31%), Positives = 284/623 (45%), Gaps = 54/623 (8%) Query: 99 LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158 L+ + +LDRE+ Y ++++ D +P SS A + V+I D NDN PQF TY Sbjct: 358 LIVKGTLDREQKDSYELILRVRDGGNPPR---SSQALLRVSITDVNDNSPQFERSTYEAE 414 Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ---FSIDSLSGDVSLVKTL 215 + E+ + PV+ +++A+D DVG N + Y + G T+ +D +G +S++ + Sbjct: 415 MAEN-APPGTPVL-QVRASDRDVGVNGQVEY-VFGAATESVRRLLRLDEATGWLSVLHRI 471 Query: 216 DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP--------RFYTSLFQESVS 267 D E+V R + A+D G P R++ T +++ +RD NDN P R V Sbjct: 472 DREEVAQLRFTVTARDRGQPPRTDRTTVVLAVRDENDNVPVVEIRKIGRIPVRDGAALVP 531 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMT-DKDYT----GNVDLP-------ITIDPRS 315 ENV + + VQ D D+G N +T T+ D +T G LP + + Sbjct: 532 ENVLVDTPVALVQVSDRDQGENGAVTCTVVGDVPFTLKPAGETVLPPLPAEDAFDRNKKK 591 Query: 316 GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375 +++TS LD ET +Y + + A D G P S+ ++ F EV Sbjct: 592 YFLHTSALLDYETTKEYSVTIVAVDSGSPSLSSNSSLMVRVVDINDHPPIFAQSVVEVHF 651 Query: 376 AEDEPPGTPVVTLTATDADEDNRLHYEIT---GGNTRGRFSITSQNGRGLITVAQPLDFK 432 AE+ PG VVT+ ATDAD + GN G F I + NG I LD + Sbjct: 652 AENNSPGERVVTVVATDADSGKNAEIAFSLDPAGN--GPFYIDADNGD--IRATGVLDRE 707 Query: 433 QERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 Q RY L V A D G S +A V I +TD N+ AP F +T V E+ + V + Sbjct: 708 QRERYELRVIAKDKGTPSLQGSATVVIQVTDRNDNAPKFAQEIFTFYVKENLLANSPVGM 767 Query: 491 VSATDSDVGINAQITY-----------SLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 V+ TD+D G NA+++ + S +A ++ F I TG I ++ Sbjct: 768 VTVTDADEGENAELSLFVEIGGPEERKMVGSTEDEDAEKGQEEMFSIENNTGTIFSSASF 827 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF---KQQLYTANIMEDALV 596 DRE +S Y V A DGG P + T V + V D NDN P + YT + + Sbjct: 828 DREKLSIYTFRVRAVDGGEPRKTATATVSLFVTDENDNAPSITSPANESYTL-LPPASSA 886 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 T V V A D+D GLN + Y L F I +GVI + L+R H L Sbjct: 887 RTVVRTVKAVDSDSGLNADLRYAL-VGGNPYRLFEIGHTNGVITLAEPLERRHRGLHRLV 945 Query: 657 AVAIDGGTPPQSSTVIVHIKIED 679 D G P +T +VHI I D Sbjct: 946 VRVTDSGIPSLCATALVHIFIND 968 Score = 229 bits (560), Expect = 8e-58 Identities = 189/643 (29%), Positives = 281/643 (43%), Gaps = 51/643 (7%) Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332 G I RV+A G N E + D+P + + G LDRE + Y Sbjct: 315 GSPITRVEALGDRRGRNGENGGARSTVFKLQVADIPD--GEKQPQLIVKGTLDREQKDSY 372 Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392 +L++ DGG+PPRS+ A F YE E+AE+ PPGTPV+ + A+D Sbjct: 373 ELILRVRDGGNPPRSSQALLRVSITDVNDNSPQFERSTYEAEMAENAPPGTPVLQVRASD 432 Query: 393 ADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG-- 448 D + ++ Y R + G ++V +D ++ + TV+A D G Sbjct: 433 RDVGVNGQVEYVFGAATESVRRLLRLDEATGWLSVLHRIDREEVAQLRFTVTARDRGQPP 492 Query: 449 RSDTAMVQINITDANNYAPVFE-----NAPY---TASVFEDAPIGTTVLVVSATDSDVGI 500 R+D V + + D N+ PV E P A V E+ + T V +V +D D G Sbjct: 493 RTDRTTVVLAVRDENDNVPVVEIRKIGRIPVRDGAALVPENVLVDTPVALVQVSDRDQGE 552 Query: 501 NAQITYSLSSEI------SNEAVAHH---DQQFVINPQTGAITTNKLLDRETMSGYLLTV 551 N +T ++ ++ + E V + F N + + T+ LLD ET Y +T+ Sbjct: 553 NGAVTCTVVGDVPFTLKPAGETVLPPLPAEDAFDRNKKKYFLHTSALLDYETTKEYSVTI 612 Query: 552 TARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG 611 A D G PSLS + + + VVD+ND+ P+F Q + + E+ G V V ATDAD G Sbjct: 613 VAVDSGSPSLSSNSSLMVRVVDINDHPPIFAQSVVEVHFAENNSPGERVVTVVATDADSG 672 Query: 612 LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671 N I + LDP G F ID +G IR LDRE ++L+ +A D GTP + Sbjct: 673 KNAEIAFSLDPAG--NGPFYIDADNGDIRATGVLDREQRERYELRVIAKDKGTPSLQGSA 730 Query: 672 IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK-GGD 730 V I++ D ND+ P F + TFY+ EN + +G + D DEG NA + ++ GG Sbjct: 731 TVVIQVTDRNDNAPKFAQEIFTFYVKENLLANSPVGMVTVTDADEGENAELSLFVEIGGP 790 Query: 731 DSNSFSLETRQGSDKAELVTMVDLDYES---------PRKK---YELVIRA---ASPPLW 775 + T + M ++ + R+K Y +RA P Sbjct: 791 EERKMVGSTEDEDAEKGQEEMFSIENNTGTIFSSASFDREKLSIYTFRVRAVDGGEPRKT 850 Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR-----VPAYDAD--VTDKLQ 828 V + VTD NDNAP + N P R V A D+D + L+ Sbjct: 851 ATATVSLFVTDENDNAPSITS---PANESYTLLPPASSARTVVRTVKAVDSDSGLNADLR 907 Query: 829 YRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 Y ++ GN L + T G +TL+ L L + V VTD Sbjct: 908 YALVGGNPYRLFEIGHTNGVITLAEPLERRHRGLHRLVVRVTD 950 Score = 205 bits (500), Expect = 2e-50 Identities = 192/649 (29%), Positives = 290/649 (44%), Gaps = 85/649 (13%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++++ D ND+SP FE YEA + E A GT VL ++A+D+D+G N +VEY T Sbjct: 393 RVSITDVNDNSPQFERSTYEAEMAENAPPGTPVLQVRASDRDVGVNGQVEYVFGAATES- 451 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 V+ + R+D +G L +DRE+VA+ V A D+ P R Sbjct: 452 ----------------VRRLLRLDEATGWLSVLHRIDREEVAQLRFTVTARDRGQP--PR 493 Query: 130 LSSTATIHVNIIDDNDNYP--------QFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181 T T+ + + D+NDN P + + V E++ V D PV A ++ +D D Sbjct: 494 TDRT-TVVLAVRDENDNVPVVEIRKIGRIPVRDGAALVPENVLV-DTPV-ALVQVSDRDQ 550 Query: 182 GANSAIRYAIIG---------GNTQMQ-------FSIDSLSGDVSLVKTLDYEQVRSYRL 225 G N A+ ++G G T + F + + LDYE + Y + Sbjct: 551 GENGAVTCTVVGDVPFTLKPAGETVLPPLPAEDAFDRNKKKYFLHTSALLDYETTKEYSV 610 Query: 226 VIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD 285 I A D GSPS S+ + L++ + D+ND+ P F S+ + +EN G +V V A DAD Sbjct: 611 TIVAVDSGSPSLSSNSSLMVRVVDINDHPPIFAQSVVEVHFAENNSPGERVVTVVATDAD 670 Query: 286 EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP 345 G NAE+ +++ D GN P ID +G + +G LDRE + +Y+L V A D G P Sbjct: 671 SGKNAEIAFSL---DPAGNG--PFYIDADNGDIRATGVLDREQRERYELRVIAKDKGTPS 725 Query: 346 RSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR----LHY 401 +AT F + + E+ +PV +T TDADE L Sbjct: 726 LQGSATVVIQVTDRNDNAPKFAQEIFTFYVKENLLANSPVGMVTVTDADEGENAELSLFV 785 Query: 402 EITG-------GNT------RGRFSITS-QNGRGLITVAQPLDFKQERRYVLTVSATDSG 447 EI G G+T +G+ + S +N G I + D ++ Y V A D G Sbjct: 786 EIGGPEERKMVGSTEDEDAEKGQEEMFSIENNTGTIFSSASFDREKLSIYTFRVRAVDGG 845 Query: 448 --GRSDTAMVQINITDANNYAP-VFENAPYTASVFEDAPIGTTVL-VVSATDSDVGINAQ 503 ++ TA V + +TD N+ AP + A + ++ A TV+ V A DSD G+NA Sbjct: 846 EPRKTATATVSLFVTDENDNAPSITSPANESYTLLPPASSARTVVRTVKAVDSDSGLNAD 905 Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD 563 + Y+L + + F I G IT + L+R + L V D G+PSL Sbjct: 906 LRYALVG-------GNPYRLFEIGHTNGVITLAEPLERRHRGLHRLVVRVTDSGIPSLCA 958 Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612 T V I + N+ + L A I S+ G D+D L Sbjct: 959 TALVHIFI-----NDSLANASLVEAQIARSLAAPLSLDIAGDPDSDRSL 1002 Score = 156 bits (379), Expect = 7e-36 Identities = 113/391 (28%), Positives = 183/391 (46%), Gaps = 37/391 (9%) Query: 429 LDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD++ + Y +T+ A DSG S + + + + D N++ P+F + E+ G Sbjct: 600 LDYETTKEYSVTIVAVDSGSPSLSSNSSLMVRVVDINDHPPIFAQSVVEVHFAENNSPGE 659 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 V+ V ATD+D G NA+I +SL + F I+ G I +LDRE Sbjct: 660 RVVTVVATDADSGKNAEIAFSLDPAGNGP--------FYIDADNGDIRATGVLDREQRER 711 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y L V A+D G PSL + V I V D NDN P F Q+++T + E+ L + V V T Sbjct: 712 YELRVIAKDKGTPSLQGSATVVIQVTDRNDNAPKFAQEIFTFYVKENLLANSPVGMVTVT 771 Query: 607 DADVGLNGRIHYELD---PKDR--------------EEGSFVIDPASGVIRTNKALDRES 649 DAD G N + ++ P++R +E F I+ +G I ++ + DRE Sbjct: 772 DADEGENAELSLFVEIGGPEERKMVGSTEDEDAEKGQEEMFSIENNTGTIFSSASFDREK 831 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY--ISENSPIGTTIG 707 ++ + + A+DGG P +++T V + + D ND+ P S Y + S T + Sbjct: 832 LSIYTFRVRAVDGGEPRKTATATVSLFVTDENDNAPSITSPANESYTLLPPASSARTVVR 891 Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 ++A D D G NA + Y++ GG+ F + G ++T+ + R + LV+ Sbjct: 892 TVKAVDSDSGLNADLRYALVGGNPYRLFEIGHTNG-----VITLAEPLERRHRGLHRLVV 946 Query: 768 RAAS---PPLWNDVRVEILVTDVNDNAPVMK 795 R P L V I + D NA +++ Sbjct: 947 RVTDSGIPSLCATALVHIFINDSLANASLVE 977 >UniRef50_UPI00006A0F39 Cluster: Protocadherin alpha 13 precursor (PCDH-alpha13).; n=6; Xenopus tropicalis|Rep: Protocadherin alpha 13 precursor (PCDH-alpha13). - Xenopus tropicalis Length = 779 Score = 238 bits (583), Expect = 1e-60 Identities = 175/608 (28%), Positives = 291/608 (47%), Gaps = 34/608 (5%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F ++ +G L +DRE V T + + +A V + + + + I D NDN P Sbjct: 85 FNVNLENGNLYVADRIDRESVCEMTPICSLSLEA--VVENPLNIFHVEIEIKDINDNSPS 142 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG-- 207 FS+ T + + E ++ A D D G NS Y I N + ++ + S Sbjct: 143 FSKDTMNLEITELTHPGTRFILGD--ALDPDDGMNSLQAYDI-SKNEYFKLNVKTSSDGR 199 Query: 208 ---DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 ++ L + LD E+ + ++++ A DGG P+R+ + + I I D+NDN+P F L+Q Sbjct: 200 MIPELVLERPLDREKQSALQIILTALDGGIPARTGISMIKIIISDINDNSPLFSQELYQV 259 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 S++E+ P+ ++++ A DADEGVN +TY ++ + TID +G + T G L Sbjct: 260 SLTESAPVNTLVIQMNATDADEGVNGHITYYLS--RISKAAQQKFTIDTETGEIRTKGTL 317 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 D ET Y+++V A DGG + A + + E+ PGT Sbjct: 318 DFETTKAYEMIVEAQDGGG--LFSNAKVVIQIVDANDNAPEIILTSVSNSIPENSVPGTV 375 Query: 385 VVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGL-ITVAQPLDFKQERRYVLTV 441 + + D D E+ ++ +IT F ITS + + + LD ++ Y +T+ Sbjct: 376 IALINIRDIDSGENGNVYCQIT---DLLPFEITSSSSNYFRLLTTRNLDREEMHEYNITI 432 Query: 442 SATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499 ATD G S T +++ + D N+ PVF A Y + E+ P G++V V A+D D+ Sbjct: 433 KATDRGSPSLSTTKTIKLVLLDVNDNPPVFGQASYVVYIPENNPSGSSVFQVQASDPDLD 492 Query: 500 INAQITYS-LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558 NA+ITYS +++ N V+ + IN TG + + D E + + + V A+D G Sbjct: 493 DNAKITYSIMNTNTDNFPVSSY---ISINSMTGILYAQRPFDYEQLREFGIQVMAKDNGS 549 Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQQLYTAN-------IMEDALVGTSVSQVGATDADVG 611 P L+ TT V I + D+NDN P +A+ + + G V++V A DAD G Sbjct: 550 PPLNSTTTVTICITDLNDNSPKILYPSTSADDSAQFEIVPRTSNKGELVAKVVAVDADSG 609 Query: 612 LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671 N + YE + E SF I +G IRT + + L + D G+PP+S+T+ Sbjct: 610 HNAWLSYEF-LQVSESMSFTISRHTGEIRTLRVFPEKETLKQRLVVLVKDNGSPPRSATI 668 Query: 672 IVHIKIED 679 +++ + D Sbjct: 669 NLNLVVAD 676 Score = 223 bits (546), Expect = 4e-56 Identities = 167/604 (27%), Positives = 285/604 (47%), Gaps = 29/604 (4%) Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ-DGGSPSRSNTTQLLINIRDVNDNAPRFY 258 F+++ +G++ + +D E V + + + N + I I+D+NDN+P F Sbjct: 85 FNVNLENGNLYVADRIDRESVCEMTPICSLSLEAVVENPLNIFHVEIEIKDINDNSPSFS 144 Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS-GW 317 ++E G + A D D+G+N+ Y ++ +Y +++ + D R Sbjct: 145 KDTMNLEITELTHPGTRFILGDALDPDDGMNSLQAYDISKNEYF-KLNVKTSSDGRMIPE 203 Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377 + LDRE Q+ Q+++TA DGG P R+ + F Y+V L E Sbjct: 204 LVLERPLDREKQSALQIILTALDGGIPARTGISMIKIIISDINDNSPLFSQELYQVSLTE 263 Query: 378 DEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435 P T V+ + ATDADE + + Y ++ + + T G I LDF+ + Sbjct: 264 SAPVNTLVIQMNATDADEGVNGHITYYLSRISKAAQQKFTIDTETGEIRTKGTLDFETTK 323 Query: 436 RYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495 Y + V A D GG A V I I DAN+ AP + S+ E++ GT + +++ D Sbjct: 324 AYEMIVEAQDGGGLFSNAKVVIQIVDANDNAPEIILTSVSNSIPENSVPGTVIALINIRD 383 Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555 D G N + ++ + E + F + T + LDRE M Y +T+ A D Sbjct: 384 IDSGENGNVYCQITDLLPFEITSSSSNYF-------RLLTTRNLDREEMHEYNITIKATD 436 Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615 G PSLS T +++ ++DVNDN PVF Q Y I E+ G+SV QV A+D D+ N + Sbjct: 437 RGSPSLSTTKTIKLVLLDVNDNPPVFGQASYVVYIPENNPSGSSVFQVQASDPDLDDNAK 496 Query: 616 IHYELDPKDREE---GSFV-IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671 I Y + + + S++ I+ +G++ + D E + ++ +A D G+PP +ST Sbjct: 497 ITYSIMNTNTDNFPVSSYISINSMTGILYAQRPFDYEQLREFGIQVMAKDNGSPPLNSTT 556 Query: 672 IVHIKIEDINDSPP--VFES----DCLTF-YISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 V I I D+ND+ P ++ S D F + S G + ++ A D D G NA + Y Sbjct: 557 TVTICITDLNDNSPKILYPSTSADDSAQFEIVPRTSNKGELVAKVVAVDADSGHNAWLSY 616 Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTM-VDLDYESPRKKYELVIR-AASPPLWNDVRVEI 782 +S SF++ G E+ T+ V + E+ +++ ++++ SPP + + + Sbjct: 617 EFLQVSESMSFTISRHTG----EIRTLRVFPEKETLKQRLVVLVKDNGSPPRSATINLNL 672 Query: 783 LVTD 786 +V D Sbjct: 673 VVAD 676 Score = 208 bits (507), Expect = 2e-51 Identities = 143/439 (32%), Positives = 225/439 (51%), Gaps = 23/439 (5%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSI-TSQNGRGL- 422 F +E+ E PGT + A D D+ N L N + ++ TS +GR + Sbjct: 143 FSKDTMNLEITELTHPGTRFILGDALDPDDGMNSLQAYDISKNEYFKLNVKTSSDGRMIP 202 Query: 423 -ITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVF 479 + + +PLD +++ + ++A D G R+ +M++I I+D N+ +P+F Y S+ Sbjct: 203 ELVLERPLDREKQSALQIILTALDGGIPARTGISMIKIIISDINDNSPLFSQELYQVSLT 262 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E AP+ T V+ ++ATD+D G+N ITY LS IS A Q+F I+ +TG I T L Sbjct: 263 ESAPVNTLVIQMNATDADEGVNGHITYYLS-RISKAA----QQKFTIDTETGEIRTKGTL 317 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 D ET Y + V A+DGG L V I +VD NDN P + +I E+++ GT Sbjct: 318 DFETTKAYEMIVEAQDGG--GLFSNAKVVIQIVDANDNAPEIILTSVSNSIPENSVPGTV 375 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR--TNKALDRESVATHDLKA 657 ++ + D D G NG ++ ++ E + +S R T + LDRE + +++ Sbjct: 376 IALINIRDIDSGENGNVYCQITDLLPFE---ITSSSSNYFRLLTTRNLDREEMHEYNITI 432 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A D G+P S+T + + + D+ND+PPVF YI EN+P G+++ +++A DPD Sbjct: 433 KATDRGSPSLSTTKTIKLVLLDVNDNPPVFGQASYVVYIPENNPSGSSVFQVQASDPDLD 492 Query: 718 PNAVVHYSIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPP 773 NA + YSI + N S S L DYE R+ + + + A SPP Sbjct: 493 DNAKITYSIMNTNTDNFPVSSYISINSMTGILYAQRPFDYEQLRE-FGIQVMAKDNGSPP 551 Query: 774 LWNDVRVEILVTDVNDNAP 792 L + V I +TD+NDN+P Sbjct: 552 LNSTTTVTICITDLNDNSP 570 Score = 167 bits (406), Expect = 4e-39 Identities = 128/404 (31%), Positives = 193/404 (47%), Gaps = 21/404 (5%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 V+I I D N+ +P F + E GT ++ A D D G+N+ Y +S N Sbjct: 129 VEIEIKDINDNSPSFSKDTMNLEITELTHPGTRFILGDALDPDDGMNSLQAYDISK---N 185 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 E + + + + LDRE S + +TA DGG+P+ + + ++I + D+ Sbjct: 186 EYFKLNVKTSSDGRMIPELVLERPLDREKQSALQIILTALDGGIPARTGISMIKIIISDI 245 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR-EEGSFVID 633 NDN P+F Q+LY ++ E A V T V Q+ ATDAD G+NG I Y L + + F ID Sbjct: 246 NDNSPLFSQELYQVSLTESAPVNTLVIQMNATDADEGVNGHITYYLSRISKAAQQKFTID 305 Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693 +G IRT LD E+ +++ A DGG ++ V+ I+I D ND+ P ++ Sbjct: 306 TETGEIRTKGTLDFETTKAYEMIVEAQDGGGLFSNAKVV--IQIVDANDNAPEIILTSVS 363 Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753 I ENS GT I I D D G N V+ I D F + T S+ L+T + Sbjct: 364 NSIPENSVPGTVIALINIRDIDSGENGNVYCQI---TDLLPFEI-TSSSSNYFRLLTTRN 419 Query: 754 LDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV 810 LD E +Y + I+A SP L +++++ DVNDN PV + ++ Sbjct: 420 LDREE-MHEYNITIKATDRGSPSLSTTKTIKLVLLDVNDNPPVFGQASYVVYIPENNPSG 478 Query: 811 GPFGRVPAYDADVTD--KLQYRILSGNNANL-----ILLNETTG 847 +V A D D+ D K+ Y I++ N N I +N TG Sbjct: 479 SSVFQVQASDPDLDDNAKITYSIMNTNTDNFPVSSYISINSMTG 522 Score = 161 bits (392), Expect = 2e-37 Identities = 134/471 (28%), Positives = 213/471 (45%), Gaps = 46/471 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I + D ND+SP+F + Y+ S+ E A T V+ + ATD D G N + Y + ++ Sbjct: 239 KIIISDINDNSPLFSQELYQVSLTESAPVNTLVIQMNATDADEGVNGHITYYLSRISK-- 296 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 Q F ID +G + T+ +LD E Y ++V+A D Sbjct: 297 ---------------AAQQKFTIDTETGEIRTKGTLDFETTKAYEMIVEAQDGGG----- 336 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L S A + + I+D NDN P+ + + S+ E+ SV VIA I D D G N + Sbjct: 337 LFSNAKVVIQIVDANDNAPEIILTSVSNSIPEN-SVPGT-VIALINIRDIDSGENGNVYC 394 Query: 190 AIIGGNTQMQFSIDSLSGD---VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 I + F I S S + + + LD E++ Y + I+A D GSPS S T + + Sbjct: 395 QI---TDLLPFEITSSSSNYFRLLTTRNLDREEMHEYNITIKATDRGSPSLSTTKTIKLV 451 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN-- 304 + DVNDN P F + + + EN P G S+ +VQA D D NA++TY++ + + T N Sbjct: 452 LLDVNDNPPVFGQASYVVYIPENNPSGSSVFQVQASDPDLDDNAKITYSIMNTN-TDNFP 510 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 V I+I+ +G +Y D E ++ + V A D G PP ++T T Sbjct: 511 VSSYISINSMTGILYAQRPFDYEQLREFGIQVMAKDNGSPPLNSTTTVTICITDLNDNSP 570 Query: 365 XFM--------PGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSI 414 + Q+E+ + G V + A DAD + L YE + F+I Sbjct: 571 KILYPSTSADDSAQFEI-VPRTSNKGELVAKVVAVDADSGHNAWLSYEFLQVSESMSFTI 629 Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNY 465 + G I + K+ + L V D+G +A + +N+ A+N+ Sbjct: 630 SRHTGE--IRTLRVFPEKETLKQRLVVLVKDNGSPPRSATINLNLVVADNF 678 >UniRef50_A7SSF2 Cluster: Predicted protein; n=2; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 814 Score = 237 bits (581), Expect = 2e-60 Identities = 141/428 (32%), Positives = 229/428 (53%), Gaps = 24/428 (5%) Query: 164 SVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY 223 +VT + + A D D G N + Y I+ + + F+ +S +G VSL LD E V Y Sbjct: 400 NVTSGTQVLTLFAHDRDEGINGQVFYYIVTSSVKGVFTTNSTTGVVSLTAELDRESVYQY 459 Query: 224 RLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY- 282 +++ AQDGGSP R+ + + + + D NDN P F T + +SE IG I+RV A Sbjct: 460 NMLVVAQDGGSPPRTASAHVKVEVLDCNDNPPVFTTLYYTLQLSEATSIGTRILRVSAND 519 Query: 283 --DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD 340 D DEGVNAE+ Y + D V +I+ +G + +D E ++ Y V A+D Sbjct: 520 RDDKDEGVNAEIRYFLKD----AIVSKKFSINDTTGQITIKQAVDYEERSSYSFEVFASD 575 Query: 341 GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNR 398 GG+ + +++ F+P +Y V+L E+ GTPV +TA+D D + + Sbjct: 576 GGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTPVTQVTASDLDSSLNGK 635 Query: 399 LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG----GRSDTAM 454 + + I GGN+ G+F + QN G++T + LD++ Y L + ATD G S M Sbjct: 636 VLFSILGGNSDGKF-VIDQN-TGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGM 693 Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 + +++ + N+ +PVF Y+AS+ E+ +G +L V+A+D D +N ++ +S+ Sbjct: 694 LHVSVVNINDNSPVFSQKMYSASIDENTTVGHVILRVTASDLDSSLNGKVLFSILE---- 749 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD--VEISVV 572 + D +FV++ TG +TTNK LD E ++ Y L + A D G P L+ + + +SVV Sbjct: 750 ---GNSDGKFVVDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVV 806 Query: 573 DVNDNEPV 580 ++NDN PV Sbjct: 807 NINDNSPV 814 Score = 237 bits (579), Expect = 4e-60 Identities = 154/438 (35%), Positives = 233/438 (53%), Gaps = 29/438 (6%) Query: 370 QYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 +YE E+ E+ GT V+TL A D DE + ++ Y I + +G F T+ + G++++ Sbjct: 392 RYEFEMYENVTSGTQVLTLFAHDRDEGINGQVFYYIVTSSVKGVF--TTNSTTGVVSLTA 449 Query: 428 PLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 LD + +Y + V A D G R+ +A V++ + D N+ PVF YT + E IG Sbjct: 450 ELDRESVYQYNMLVVAQDGGSPPRTASAHVKVEVLDCNDNPPVFTTLYYTLQLSEATSIG 509 Query: 486 TTVLVVSATD---SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 T +L VSA D D G+NA+I Y L I ++ +F IN TG IT + +D E Sbjct: 510 TRILRVSANDRDDKDEGVNAEIRYFLKDAIVSK-------KFSINDTTGQITIKQAVDYE 562 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 S Y V A DGG L+ ++ V I+++DVNDN P F Y ++E+ +GT V+Q Sbjct: 563 ERSSYSFEVFASDGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTPVTQ 622 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 V A+D D LNG++ + + +G FVID +GV+ TNK+LD E V + L A D Sbjct: 623 VTASDLDSSLNGKVLFSI-LGGNSDGKFVIDQNTGVVTTNKSLDYEDVTEYTLVIQATDC 681 Query: 663 GTPPQSSTV--IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 G PP +S+ ++H+ + +IND+ PVF + I EN+ +G I + A D D N Sbjct: 682 GDPPLNSSQPGMLHVSVVNINDNSPVFSQKMYSASIDENTTVGHVILRVTASDLDSSLNG 741 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWND 777 V +SI G+ F ++ G + T LDYE +Y LVI+A PPL + Sbjct: 742 KVLFSILEGNSDGKFVVDQNTG----VVTTNKSLDYEDV-TEYTLVIQATDCGDPPLNSS 796 Query: 778 V--RVEILVTDVNDNAPV 793 + + V ++NDN+PV Sbjct: 797 QPGMLHVSVVNINDNSPV 814 Score = 237 bits (579), Expect = 4e-60 Identities = 143/436 (32%), Positives = 237/436 (54%), Gaps = 25/436 (5%) Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321 ++ + ENV G ++ + A+D DEG+N ++ Y + T +V T + +G V + Sbjct: 393 YEFEMYENVTSGTQVLTLFAHDRDEGINGQVFYYIV----TSSVKGVFTTNSTTGVVSLT 448 Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381 +LDRE+ +Y +LV A DGG PPR+A+A F Y ++L+E Sbjct: 449 AELDRESVYQYNMLVVAQDGGSPPRTASAHVKVEVLDCNDNPPVFTTLYYTLQLSEATSI 508 Query: 382 GTPVVTLTATDADEDN-----RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436 GT ++ ++A D D+ + + Y + +FSI G+ IT+ Q +D+++ Sbjct: 509 GTRILRVSANDRDDKDEGVNAEIRYFLKDAIVSKKFSINDTTGQ--ITIKQAVDYEERSS 566 Query: 437 YVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494 Y V A+D G + ++ V+I I D N+ P F Y + E+ IGT V V+A+ Sbjct: 567 YSFEVFASDGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTPVTQVTAS 626 Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554 D D +N ++ +S+ + D +FVI+ TG +TTNK LD E ++ Y L + A Sbjct: 627 DLDSSLNGKVLFSILG-------GNSDGKFVIDQNTGVVTTNKSLDYEDVTEYTLVIQAT 679 Query: 555 DGGVPSLSDTTD--VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612 D G P L+ + + +SVV++NDN PVF Q++Y+A+I E+ VG + +V A+D D L Sbjct: 680 DCGDPPLNSSQPGMLHVSVVNINDNSPVFSQKMYSASIDENTTVGHVILRVTASDLDSSL 739 Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV- 671 NG++ + + + +G FV+D +GV+ TNK+LD E V + L A D G PP +S+ Sbjct: 740 NGKVLFSI-LEGNSDGKFVVDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQP 798 Query: 672 -IVHIKIEDINDSPPV 686 ++H+ + +IND+ PV Sbjct: 799 GMLHVSVVNINDNSPV 814 Score = 202 bits (494), Expect = 8e-50 Identities = 139/452 (30%), Positives = 223/452 (49%), Gaps = 37/452 (8%) Query: 26 QQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXX 85 ++YE + E +SGT VLTL A D+D G N +V Y I VT+ Sbjct: 391 RRYEFEMYENVTSGTQVLTLFAHDRDEGINGQVFYYI--VTSS----------------- 431 Query: 86 VQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145 V+ VF + +G + A LDRE V +Y +LV A D SP +++A + V ++D ND Sbjct: 432 VKGVFTTNSTTGVVSLTAELDRESVYQYNMLVVAQDGGSPPR---TASAHVKVEVLDCND 488 Query: 146 NYPQFSEKTYTVSVDEDISVTDNPV-IAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS 204 N P F+ YT+ + E S+ + ++ D D G N+ IRY + +FSI+ Sbjct: 489 NPPVFTTLYYTLQLSEATSIGTRILRVSANDRDDKDEGVNAEIRYFLKDAIVSKKFSIND 548 Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 +G +++ + +DYE+ SY + A DGG + ++ + I I DVNDN P F + + Sbjct: 549 TTGQITIKQAVDYEERSSYSFEVFASDGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYV 608 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 + ENV IG + +V A D D +N ++ +++ GN D ID +G V T+ L Sbjct: 609 QLVENVAIGTPVTQVTASDLDSSLNGKVLFSILG----GNSDGKFVIDQNTGVVTTNKSL 664 Query: 325 DRETQAKYQLLVTATDGGDPP--RSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382 D E +Y L++ ATD GDPP S F Y + E+ G Sbjct: 665 DYEDVTEYTLVIQATDCGDPPLNSSQPGMLHVSVVNINDNSPVFSQKMYSASIDENTTVG 724 Query: 383 TPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440 ++ +TA+D D + ++ + I GN+ G+F + QN G++T + LD++ Y L Sbjct: 725 HVILRVTASDLDSSLNGKVLFSILEGNSDGKF-VVDQN-TGVVTTNKSLDYEDVTEYTLV 782 Query: 441 VSATDSG----GRSDTAMVQINITDANNYAPV 468 + ATD G S M+ +++ + N+ +PV Sbjct: 783 IQATDCGDPPLNSSQPGMLHVSVVNINDNSPV 814 Score = 190 bits (463), Expect = 5e-46 Identities = 130/409 (31%), Positives = 201/409 (49%), Gaps = 25/409 (6%) Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ-FSIDSLS 206 P F++ Y+ + ED +V + + A D D N+ + Y+I+ +T+ F ID+++ Sbjct: 1 PIFNQTLYSAIIPEDFTV--GGTLLTVLARDQDAALNARVTYSIVSFSTESDYFVIDNIT 58 Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266 G V K DYE R Y +RA+D GSP RS + + I D NDN P F ++ V Sbjct: 59 GVVRSSKEFDYETQRMYSFSVRAEDRGSPIRSAIATIHVQITDTNDNRPIFQPMEYETRV 118 Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326 SEN P+G + RV+A D D NA+L Y++ + GN + TID +G + T + D Sbjct: 119 SENTPLGTIVARVKAVDKDSTSNADLIYSIQN----GNNNGSFTIDNSTGEIMTRKEFDF 174 Query: 327 ETQAKYQLLVTATDGGDPPRSAT--ATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 E +Y L ++ +D G P S+ A F +Y + E+ GT Sbjct: 175 EKTERYNLTISVSDTGVPALSSLNFANVVIIVVDENDNPPEFAQKRYTATVYENFTVGTV 234 Query: 385 VVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 V+ +TA D D + L Y I GNT F I + +G I++ +PLD + Y L + Sbjct: 235 VLRVTAHDKDSGPNAMLKYSIHSGNTDDAFVIIADSGD--ISLDKPLDKETIENYTLVLI 292 Query: 443 ATDSG----GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498 TD G +V + ++ N +AP F N Y AS+ E+ P+GT+++ V A + DV Sbjct: 293 VTDMGIPPLESIKRMVVNVIVSGVNEHAPRFLNEFYNASIPENLPLGTSIVRVRAVEDDV 352 Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 + A+ Y + S++ F++N QTG IT + LD ET Y Sbjct: 353 SVGARFIYVIKDAASSKV-------FLVN-QTGDITLARELDYETRRRY 393 Score = 187 bits (455), Expect = 4e-45 Identities = 133/423 (31%), Positives = 198/423 (46%), Gaps = 36/423 (8%) Query: 21 PVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXX 80 P+F Y A + E + G T+LT+ A DQD NA V Y+I + ++ Sbjct: 1 PIFNQTLYSAIIPEDFTVGGTLLTVLARDQDAALNARVTYSIVSFSTES----------- 49 Query: 81 XXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNI 140 D F ID +G + + D E Y+ V+A D+ SP+ S+ ATIHV I Sbjct: 50 -------DYFVIDNITGVVRSSKEFDYETQRMYSFSVRAEDRGSPIR---SAIATIHVQI 99 Query: 141 IDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQF 200 D NDN P F Y V E+ + ++A++KA D D +N+ + Y+I GN F Sbjct: 100 TDTNDNRPIFQPMEYETRVSENTPL--GTIVARVKAVDKDSTSNADLIYSIQNGNNNGSF 157 Query: 201 SIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS--NTTQLLINIRDVNDNAPRFY 258 +ID+ +G++ K D+E+ Y L I D G P+ S N ++I + D NDN P F Sbjct: 158 TIDNSTGEIMTRKEFDFEKTERYNLTISVSDTGVPALSSLNFANVVIIVVDENDNPPEFA 217 Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV 318 + +V EN +G ++RV A+D D G NA L Y++ ++GN D I SG + Sbjct: 218 QKRYTATVYENFTVGTVVLRVTAHDKDSGPNAMLKYSI----HSGNTDDAFVIIADSGDI 273 Query: 319 YTSGQLDRETQAKYQLLVTATDGGDPPRSA--TATXXXXXXXXXXXXXXFMPGQYEVELA 376 LD+ET Y L++ TD G PP + F+ Y + Sbjct: 274 SLDKPLDKETIENYTLVLIVTDMGIPPLESIKRMVVNVIVSGVNEHAPRFLNEFYNASIP 333 Query: 377 EDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434 E+ P GT +V + A + D R Y I + F + N G IT+A+ LD++ Sbjct: 334 ENLPLGTSIVRVRAVEDDVSVGARFIYVIKDAASSKVFLV---NQTGDITLARELDYETR 390 Query: 435 RRY 437 RRY Sbjct: 391 RRY 393 Score = 186 bits (454), Expect = 6e-45 Identities = 115/347 (33%), Positives = 188/347 (54%), Gaps = 33/347 (9%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKAT---DQDIGKNAEVEYTIEL 64 H ++ VLDCND+ PVF Y + E S GT +L + A D+D G NAE+ Y + Sbjct: 478 HVKVEVLDCNDNPPVFTTLYYTLQLSEATSIGTRILRVSANDRDDKDEGVNAEIRYFL-- 535 Query: 65 VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS 124 +DA V F I+ +G + + ++D E+ + Y+ V A+D Sbjct: 536 --------KDA---------IVSKKFSINDTTGQITIKQAVDYEERSSYSFEVFASDGGE 578 Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184 RL+ ++++ + IID NDN P F Y V + E++++ PV ++ A+D D N Sbjct: 579 A---RLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAI-GTPV-TQVTASDLDSSLN 633 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQ 242 + ++I+GGN+ +F ID +G V+ K+LDYE V Y LVI+A D G P + S Sbjct: 634 GKVLFSILGGNSDGKFVIDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSSQPGM 693 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 L +++ ++NDN+P F ++ S+ EN +G+ I+RV A D D +N ++ +++ + Sbjct: 694 LHVSVVNINDNSPVFSQKMYSASIDENTTVGHVILRVTASDLDSSLNGKVLFSILE---- 749 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT 349 GN D +D +G V T+ LD E +Y L++ ATD GDPP +++ Sbjct: 750 GNSDGKFVVDQNTGVVTTNKSLDYEDVTEYTLVIQATDCGDPPLNSS 796 Score = 186 bits (452), Expect = 1e-44 Identities = 133/418 (31%), Positives = 209/418 (50%), Gaps = 26/418 (6%) Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 P+F Y+A + ED +G T+L V A D D +NA++TYS+ S S E+ FVI Sbjct: 1 PIFNQTLYSAIIPEDFTVGGTLLTVLARDQDAALNARVTYSIVS-FSTES-----DYFVI 54 Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586 + TG + ++K D ET Y +V A D G P S + + + D NDN P+F+ Y Sbjct: 55 DNITGVVRSSKEFDYETQRMYSFSVRAEDRGSPIRSAIATIHVQITDTNDNRPIFQPMEY 114 Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646 + E+ +GT V++V A D D N + Y + GSF ID ++G I T K D Sbjct: 115 ETRVSENTPLGTIVARVKAVDKDSTSNADLIYSIQ-NGNNNGSFTIDNSTGEIMTRKEFD 173 Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKI--EDINDSPPVFESDCLTFYISENSPIGT 704 E ++L D G P SS ++ I D ND+PP F T + EN +GT Sbjct: 174 FEKTERYNLTISVSDTGVPALSSLNFANVVIIVVDENDNPPEFAQKRYTATVYENFTVGT 233 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764 + + AHD D GPNA++ YSI G+ ++F + +D ++ LD E+ + Y Sbjct: 234 VVLRVTAHDKDSGPNAMLKYSIHSGNTDDAFVII----ADSGDISLDKPLDKET-IENYT 288 Query: 765 LVIRAAS---PPLWNDVR--VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPA 818 LV+ PPL + R V ++V+ VN++AP + + + + P+G RV A Sbjct: 289 LVLIVTDMGIPPLESIKRMVVNVIVSGVNEHAPRFLN-EFYNASIPENLPLGTSIVRVRA 347 Query: 819 YDADVT--DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV--SVTDG 872 + DV+ + Y I ++ + L+N+ TG +TL+ +L+ + E+ +VT G Sbjct: 348 VEDDVSVGARFIYVIKDAASSKVFLVNQ-TGDITLARELDYETRRRYEFEMYENVTSG 404 Score = 179 bits (436), Expect = 9e-43 Identities = 109/329 (33%), Positives = 175/329 (53%), Gaps = 31/329 (9%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 IH QI D ND+ P+F+ +YE V E GT V +KA D+D NA++ Y+I+ Sbjct: 95 IHVQIT--DTNDNRPIFQPMEYETRVSENTPLGTIVARVKAVDKDSTSNADLIYSIQ--- 149 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 N + F ID +G ++TR D EK RY + + +D P Sbjct: 150 ----NGNNNGS------------FTIDNSTGEIMTRKEFDFEKTERYNLTISVSDTGVPA 193 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 L+ A + + ++D+NDN P+F++K YT +V E+ +V V+ ++ A D D G N+ Sbjct: 194 LSSLNF-ANVVIIVVDENDNPPEFAQKRYTATVYENFTV--GTVVLRVTAHDKDSGPNAM 250 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 ++Y+I GNT F I + SGD+SL K LD E + +Y LV+ D G P + ++++N Sbjct: 251 LKYSIHSGNTDDAFVIIADSGDISLDKPLDKETIENYTLVLIVTDMGIPPLESIKRMVVN 310 Query: 247 --IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + VN++APRF + S+ EN+P+G SIVRV+A + D V A Y + D Sbjct: 311 VIVSGVNEHAPRFLNEFYNASIPENLPLGTSIVRVRAVEDDVSVGARFIYVIKDA----- 365 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQ 333 + + ++G + + +LD ET+ +Y+ Sbjct: 366 ASSKVFLVNQTGDITLARELDYETRRRYE 394 Score = 170 bits (414), Expect = 4e-40 Identities = 129/410 (31%), Positives = 199/410 (48%), Gaps = 27/410 (6%) Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 Y ++E+ GT VL + A D D GIN Q+ Y + + S + V F N TG + Sbjct: 393 YEFEMYENVTSGTQVLTLFAHDRDEGINGQVFYYIVTS-SVKGV------FTTNSTTGVV 445 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593 + LDRE++ Y + V A+DGG P + + V++ V+D NDN PVF YT + E Sbjct: 446 SLTAELDRESVYQYNMLVVAQDGGSPPRTASAHVKVEVLDCNDNPPVFTTLYYTLQLSEA 505 Query: 594 ALVGTSVSQVGATDAD---VGLNGRIHYELDPKDR-EEGSFVIDPASGVIRTNKALDRES 649 +GT + +V A D D G+N I Y L KD F I+ +G I +A+D E Sbjct: 506 TSIGTRILRVSANDRDDKDEGVNAEIRYFL--KDAIVSKKFSINDTTGQITIKQAVDYEE 563 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 +++ + A DGG + + V I I D+ND+ P F + EN IGT + ++ Sbjct: 564 RSSYSFEVFASDGGEARLTGSSSVRITIIDVNDNRPYFLPTRYYVQLVENVAIGTPVTQV 623 Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 A D D N V +SI GG+ F ++ G + T LDYE + Y LVI+A Sbjct: 624 TASDLDSSLNGKVLFSILGGNSDGKFVIDQNTGV----VTTNKSLDYEDVTE-YTLVIQA 678 Query: 770 AS---PPLWNDV--RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDAD- 822 PPL + + + V ++NDN+PV ++ + + VG RV A D D Sbjct: 679 TDCGDPPLNSSQPGMLHVSVVNINDNSPVFSQ-KMYSASIDENTTVGHVILRVTASDLDS 737 Query: 823 -VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + K+ + IL GN+ ++++ TG +T + L+ T+ + TD Sbjct: 738 SLNGKVLFSILEGNSDGKFVVDQNTGVVTTNKSLDYEDVTEYTLVIQATD 787 Score = 157 bits (382), Expect = 3e-36 Identities = 103/318 (32%), Positives = 169/318 (53%), Gaps = 15/318 (4%) Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638 P+F Q LY+A I ED VG ++ V A D D LN R+ Y + E FVID +GV Sbjct: 1 PIFNQTLYSAIIPEDFTVGGTLLTVLARDQDAALNARVTYSIVSFSTESDYFVIDNITGV 60 Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698 +R++K D E+ + A D G+P +S+ +H++I D ND+ P+F+ +SE Sbjct: 61 VRSSKEFDYETQRMYSFSVRAEDRGSPIRSAIATIHVQITDTNDNRPIFQPMEYETRVSE 120 Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758 N+P+GT + ++A D D NA + YSI+ G+++ SF+++ G E++T + D+E Sbjct: 121 NTPLGTIVARVKAVDKDSTSNADLIYSIQNGNNNGSFTIDNSTG----EIMTRKEFDFEK 176 Query: 759 PRKKYELVIRAAS---PPL--WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF 813 ++Y L I + P L N V I+V D NDN P + Y++ F VG Sbjct: 177 -TERYNLTISVSDTGVPALSSLNFANVVIIVVDENDNPPEFAQKRYTATVYEN-FTVGTV 234 Query: 814 G-RVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVT 870 RV A+D D L+Y I SGN + ++ +G ++L L+ + T+ + VT Sbjct: 235 VLRVTAHDKDSGPNAMLKYSIHSGNTDDAFVIIADSGDISLDKPLDKETIENYTLVLIVT 294 Query: 871 D-GVNEIKAMMQLSVRLI 887 D G+ ++++ ++ V +I Sbjct: 295 DMGIPPLESIKRMVVNVI 312 Score = 67.7 bits (158), Expect = 4e-09 Identities = 45/147 (30%), Positives = 74/147 (50%), Gaps = 22/147 (14%) Query: 2 SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 S P +H ++V++ ND+SPVF + Y AS+ E + G +L + A+D D N +V ++ Sbjct: 689 SQPGMLH--VSVVNINDNSPVFSQKMYSASIDENTTVGHVILRVTASDLDSSLNGKVLFS 746 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121 I +D F +D +G + T SLD E V YT++++ATD Sbjct: 747 ILEGNSD-------------------GKFVVDQNTGVVTTNKSLDYEDVTEYTLVIQATD 787 Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYP 148 P + S +HV++++ NDN P Sbjct: 788 CGDPPLNS-SQPGMLHVSVVNINDNSP 813 Score = 55.6 bits (128), Expect = 2e-05 Identities = 55/201 (27%), Positives = 83/201 (41%), Gaps = 14/201 (6%) Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753 F + EN GT + + AHD DEG N V Y I F+ + G + + Sbjct: 395 FEMYENVTSGTQVLTLFAHDRDEGINGQVFYYIVTSSVKGVFTTNSTTGV----VSLTAE 450 Query: 754 LDYESPRKKYELVIR--AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811 LD ES + LV+ SPP V++ V D NDN PV + +G Sbjct: 451 LDRESVYQYNMLVVAQDGGSPPRTASAHVKVEVLDCNDNPPVFTTLYYTLQ-LSEATSIG 509 Query: 812 P-FGRVPAYDADVTDK-----LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATM 865 RV A D D D+ ++Y + + +N+TTG +T+ ++ + Sbjct: 510 TRILRVSANDRDDKDEGVNAEIRYFLKDAIVSKKFSINDTTGQITIKQAVDYEERSSYSF 569 Query: 866 EVSVTDGVNEIKAMMQLSVRL 886 EV +DG E + SVR+ Sbjct: 570 EVFASDG-GEARLTGSSSVRI 589 >UniRef50_Q9VJB6 Cluster: Putative neural-cadherin 2 precursor; n=5; Diptera|Rep: Putative neural-cadherin 2 precursor - Drosophila melanogaster (Fruit fly) Length = 2215 Score = 237 bits (581), Expect = 2e-60 Identities = 297/1169 (25%), Positives = 468/1169 (40%), Gaps = 142/1169 (12%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDN-----RLHYEITGG---NTRGRFSITSQ 417 F G Y + E+ G+ V+T++A D D+ N +L Y I G + Sbjct: 422 FPQGIYFGNVTENGTAGSSVMTMSAVDYDDPNESTNAKLIYSIEKNVIEEETGAPIFEIE 481 Query: 418 NGRGLI-TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA 476 GLI T LD ++ Y + V A D GG T I + D N+ P F + Sbjct: 482 PETGLIKTAVCCLDRERTPDYSIQVVAMDGGGLKGTGTASIRVKDLNDMPPQFTKDEWVT 541 Query: 477 SVFEDAPI---GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ-TGA 532 V E T +L V+ D D Q Y + + N V N TG+ Sbjct: 542 EVDETNGTYIPETPILTVTVQDEDETNTFQ--YKV---VPNSGFGADKFAMVRNGDGTGS 596 Query: 533 ITTNKLLDRET---MSGYLLTVTARDGGV--PSLSDTTDVEISVV-----DVNDNEPVFK 582 + + LD E SG+ + D G P SD V S V D+NDN P F Sbjct: 597 LKIIQPLDYEDPLQSSGFRFRIQVNDKGDDGPGGSDKYHVAYSWVVVKLRDINDNVPKFD 656 Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642 ++ +I ED VGT + Q ATDAD G + ++ Y++ + F I G + Sbjct: 657 REHIEVSIYEDTKVGTILEQFKATDADQGGHSKVAYKIVRSTNRKRQFAISDR-GAVSIQ 715 Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 + LDRE+ H ++ +AID G+P +++T + + ++D+ND+ P F D + EN Sbjct: 716 RPLDRETQDRHHIQILAIDDGSPARTATATLTVIVKDVNDNAPTFAQDYKPT-LPENVS- 773 Query: 703 GTTIGEIRAHDPDE------GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD--- 753 G I E+ A DPD+ GP + + F +E + D V ++ Sbjct: 774 GKKILEVAAKDPDDRLRGNGGPFTFRLDPLASDEIKAGFKVEYDRRGDNENGVAIISSLR 833 Query: 754 -LDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809 D E+ +K Y + I +P + + + + DVNDN ++ NY+ Sbjct: 834 PFDREA-QKSYAIPIEIKDNGAPAMTGTSTLTVTIGDVNDNKMQPGSKSVLVYNYQGQSQ 892 Query: 810 VGPFGRVPAYDA---DVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATME 866 P GRV D DV DK Y + + L+ TG +T+ +L Sbjct: 893 DTPIGRVYVNDPDDWDVPDKKYYWEVQEHQR--FKLDTDTGILTMRAGTRRGRYQLRFKV 950 Query: 867 VSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFL---SPL--------LGF 915 G +I A + ++VR IT E + + ++RL+ +T E F+ +P+ L Sbjct: 951 YDREHGQEDIPANLSVTVRDITAEAVQQAGSMRLSHITDEDFVRTWNPVKNQVEPSKLER 1010 Query: 916 FIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHL 975 F + LA ++ ++N+ +FSVQ + +V F+AR + P++ L Sbjct: 1011 FRNKLAELLYTDRDNVDVFSVQLKEGSPYPLTDVHFAAR--------SATQQPYFKAVRL 1062 Query: 976 RERVYLHRTTLARLATVQVLPFDDNICVHE---PCLNFEECLTVLKFGNASGFVNSDSVL 1032 V +HR + + + + + N C+HE C C + ++ G V+ + Sbjct: 1063 NGVVQMHREEIEKDVGLNITMVNINECLHEGKGKC-GSNSCTSKVELGKKPYTVSVNRTA 1121 Query: 1033 FRPIYPVTSFTCQC-PEGFT--GVNCETILTKASCEVDGDGSICRSGSQCVARREGGILC 1089 + S C C FT NC T +C +G +CV R G C Sbjct: 1122 LVGVRLDISAQCVCRARNFTHQDHNCRT-------------HLCYNGGRCVETRNGP-KC 1167 Query: 1090 QGCSIDAAYTTAVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNG--- 1146 C + Y C+ RSF + + +P L+ HL L+F T+ GL+LYNG Sbjct: 1168 VACPV--GYNGPRCQQSTRSFRGNGWAWYPPLQLCQESHLSLEFITRVADGLILYNGPIV 1225 Query: 1147 --RYNER--HDFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIE 1202 + E DF+ALEL G P L F G + + + + DG WH ++I Sbjct: 1226 PPKPEETVISDFIALEL------EQGYPRLLIDFGSGTLELRVKTKKTLDDGVWHRLDIF 1279 Query: 1203 YFNRTITMILDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPL 1262 + + M++D C +L + G F AR +IP L+L PL Sbjct: 1280 WDTENVRMVVDFCR--TALVSEMEDGTP---PEFDDNACQARGQIPPFA--ESLNLNQPL 1332 Query: 1263 QIGGLPN-------IPSSFQVKNKDFVGCISDFYIDHKFIDLNSYVADNGTLAGCPEKRS 1315 Q+GGL + +K F GCI + + + DL + CP+ Sbjct: 1333 QLGGLYRQHFDQTLYNWQYAFSSKGFDGCIRNVIHNSEHYDLAFPALARNSFPACPQTDE 1392 Query: 1316 RC----SSAPCYNGAECSDLWDTYICDCKEGHTGKDCADSTGPPWRFGGDGMLSFNPLLR 1371 C +A C+ C C C+ G G C T P F + F Sbjct: 1393 VCLKTEHTARCWEHGNCVASLVQAKCHCQPGWMGPGCNVPT-IPTTFKAQSYVKFALSFE 1451 Query: 1372 PIQLPWLNALSIRTRQR--DAFVMS---------IQLKSGLLHYSYNGETM-------YL 1413 P + L RTR++ + F +S ++L+ G L + YN +M L Sbjct: 1452 PDRFSTQLQLRFRTREQGGELFRVSDQHHREYAILELRRGHLQFRYNLNSMRNEEQLLTL 1511 Query: 1414 PMATLSDGAWHRIEIKWLGTDISVTVDYG 1442 ++DG WH I I G+ + +D G Sbjct: 1512 TAIAVNDGQWHVIRISRYGSAALMELDGG 1540 Score = 196 bits (477), Expect = 1e-47 Identities = 162/589 (27%), Positives = 272/589 (46%), Gaps = 58/589 (9%) Query: 198 MQFSIDSLSGDVS---LVKTLDYEQVRS---YRLVIRAQDGGSPSRSNTTQLLINIRDVN 251 MQF +D+ + S L+ LD +Q +R + AQD G + +N++D+N Sbjct: 357 MQFRVDNSFNEKSNNRLLCPLDRDQPNGRPQWRFTVFAQDEGGEGLVGYADIQVNLKDIN 416 Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD---EGVNAELTYTMTDKDYTGNVDLP 308 DNAP+F ++ +V+EN G S++ + A D D E NA+L Y++ P Sbjct: 417 DNAPQFPQGIYFGNVTENGTAGSSVMTMSAVDYDDPNESTNAKLIYSIEKNVIEEETGAP 476 Query: 309 I-TIDPRSGWVYTS-GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 I I+P +G + T+ LDRE Y + V A DGG T T F Sbjct: 477 IFEIEPETGLIKTAVCCLDRERTPDYSIQVVAMDGGG--LKGTGTASIRVKDLNDMPPQF 534 Query: 367 MPGQYEVELAEDEP---PGTPVVTLTATDADEDNRLHYEITGGNTRG--RFS-ITSQNGR 420 ++ E+ E P TP++T+T D DE N Y++ + G +F+ + + +G Sbjct: 535 TKDEWVTEVDETNGTYIPETPILTVTVQDEDETNTFQYKVVPNSGFGADKFAMVRNGDGT 594 Query: 421 GLITVAQPLDFK---QERRYVLTVSATDSG----GRSDT-----AMVQINITDANNYAPV 468 G + + QPLD++ Q + + D G G SD + V + + D N+ P Sbjct: 595 GSLKIIQPLDYEDPLQSSGFRFRIQVNDKGDDGPGGSDKYHVAYSWVVVKLRDINDNVPK 654 Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528 F+ S++ED +GT + ATD+D G ++++ Y + + + +QF I+ Sbjct: 655 FDREHIEVSIYEDTKVGTILEQFKATDADQGGHSKVAYKIVRSTNRK------RQFAISD 708 Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588 + GA++ + LDRET + + + A D G P+ + T + + V DVNDN P F Q Y Sbjct: 709 R-GAVSIQRPLDRETQDRHHIQILAIDDGSPARTATATLTVIVKDVNDNAPTFAQD-YKP 766 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGR---IHYELDP--KDREEGSFVI------DPASG 637 + E+ + G + +V A D D L G + LDP D + F + D +G Sbjct: 767 TLPEN-VSGKKILEVAAKDPDDRLRGNGGPFTFRLDPLASDEIKAGFKVEYDRRGDNENG 825 Query: 638 V--IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695 V I + + DRE+ ++ + D G P + T + + I D+ND+ S + Y Sbjct: 826 VAIISSLRPFDREAQKSYAIPIEIKDNGAPAMTGTSTLTVTIGDVNDNKMQPGSKSVLVY 885 Query: 696 ISENSPIGTTIGEIRAHDPDEG--PNAVVHYSIKGGDDSNSFSLETRQG 742 + T IG + +DPD+ P+ ++ ++ + F L+T G Sbjct: 886 NYQGQSQDTPIGRVYVNDPDDWDVPDKKYYWEVQ---EHQRFKLDTDTG 931 Score = 128 bits (310), Expect = 2e-27 Identities = 122/490 (24%), Positives = 217/490 (44%), Gaps = 61/490 (12%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDI---GKNAEVEYTIELVT 66 Q+N+ D ND++P F Y +V E ++G++V+T+ A D D NA++ Y+IE Sbjct: 409 QVNLKDINDNAPQFPQGIYFGNVTENGTAGSSVMTMSAVDYDDPNESTNAKLIYSIE--- 465 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS-LDREKVARYTVLVKATDQASP 125 + + E +F I+ +G + T LDRE+ Y++ V A D Sbjct: 466 KNVIEEETGA-----------PIFEIEPETGLIKTAVCCLDRERTPDYSIQVVAMDGGG- 513 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 L T T + + D ND PQF++ + VDE + T P + T D + Sbjct: 514 ----LKGTGTASIRVKDLNDMPPQFTKDEWVTEVDE-TNGTYIPETPILTVTVQDEDETN 568 Query: 186 AIRYAII-----GGNTQMQFSIDSLSGDVSLVKTLDYE---QVRSYRLVIRAQDGG--SP 235 +Y ++ G + +G + +++ LDYE Q +R I+ D G P Sbjct: 569 TFQYKVVPNSGFGADKFAMVRNGDGTGSLKIIQPLDYEDPLQSSGFRFRIQVNDKGDDGP 628 Query: 236 SRSNT-----TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290 S+ + +++ +RD+NDN P+F + S+ E+ +G + + +A DAD+G ++ Sbjct: 629 GGSDKYHVAYSWVVVKLRDINDNVPKFDREHIEVSIYEDTKVGTILEQFKATDADQGGHS 688 Query: 291 ELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350 ++ Y + + N I R G V LDRETQ ++ + + A D G P R+ATA Sbjct: 689 KVAYKIV---RSTNRKRQFAISDR-GAVSIQRPLDRETQDRHHIQILAIDDGSPARTATA 744 Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH--------YE 402 T F Y+ L E+ G ++ + A D D+ R + Sbjct: 745 TLTVIVKDVNDNAPTFAQ-DYKPTLPEN-VSGKKILEVAAKDPDDRLRGNGGPFTFRLDP 802 Query: 403 ITGGNTRGRFSI------TSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAM 454 + + F + ++NG +I+ +P D + ++ Y + + D+G + T+ Sbjct: 803 LASDEIKAGFKVEYDRRGDNENGVAIISSLRPFDREAQKSYAIPIEIKDNGAPAMTGTST 862 Query: 455 VQINITDANN 464 + + I D N+ Sbjct: 863 LTVTIGDVND 872 Score = 110 bits (264), Expect = 6e-22 Identities = 120/478 (25%), Positives = 210/478 (43%), Gaps = 42/478 (8%) Query: 134 ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV-IAKIKATDADVGANSAIRYAII 192 A I VN+ D NDN PQF + Y +V E+ + + + ++ + D + N+ + Y+I Sbjct: 406 ADIQVNLKDINDNAPQFPQGIYFGNVTENGTAGSSVMTMSAVDYDDPNESTNAKLIYSIE 465 Query: 193 GGNTQMQFS--IDSLSGDVSLVKT----LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 + + I + + L+KT LD E+ Y + + A DGG + T I Sbjct: 466 KNVIEEETGAPIFEIEPETGLIKTAVCCLDRERTPDYSIQVVAMDGGGLKGTGTAS--IR 523 Query: 247 IRDVNDNAPRFYTSLFQESVSEN----VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 ++D+ND P+F + V E +P I+ V D DE N + + + Sbjct: 524 VKDLNDMPPQFTKDEWVTEVDETNGTYIP-ETPILTVTVQDEDE-TNTFQYKVVPNSGFG 581 Query: 303 GNVDLPITIDPRSGWVYTSGQLDRE---TQAKYQLLVTATDGGD--PPRS-----ATATX 352 + + +G + LD E + ++ + D GD P S A + Sbjct: 582 ADKFAMVRNGDGTGSLKIIQPLDYEDPLQSSGFRFRIQVNDKGDDGPGGSDKYHVAYSWV 641 Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRG 410 F EV + ED GT + ATDAD+ +++ Y+I R Sbjct: 642 VVKLRDINDNVPKFDREHIEVSIYEDTKVGTILEQFKATDADQGGHSKVAYKIVRSTNRK 701 Query: 411 R-FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAP 467 R F+I+ RG +++ +PLD + + R+ + + A D G R+ TA + + + D N+ AP Sbjct: 702 RQFAISD---RGAVSIQRPLDRETQDRHHIQILAIDDGSPARTATATLTVIVKDVNDNAP 758 Query: 468 VFENAPYTASVFEDAPIGTTVLVVSATDSD---VGINAQITYSLSSEISNEAVA----HH 520 F Y ++ E+ G +L V+A D D G T+ L S+E A + Sbjct: 759 TFAQ-DYKPTLPENVS-GKKILEVAAKDPDDRLRGNGGPFTFRLDPLASDEIKAGFKVEY 816 Query: 521 DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578 D++ I++ + DRE Y + + +D G P+++ T+ + +++ DVNDN+ Sbjct: 817 DRRGDNENGVAIISSLRPFDREAQKSYAIPIEIKDNGAPAMTGTSTLTVTIGDVNDNK 874 Score = 105 bits (253), Expect = 1e-20 Identities = 104/396 (26%), Positives = 175/396 (44%), Gaps = 39/396 (9%) Query: 523 QFVINPQTGAITTNKLL---DRETMSG---YLLTVTARDGGVPSLSDTTDVEISVVDVND 576 QF ++ + N+LL DR+ +G + TV A+D G L D+++++ D+ND Sbjct: 358 QFRVDNSFNEKSNNRLLCPLDRDQPNGRPQWRFTVFAQDEGGEGLVGYADIQVNLKDIND 417 Query: 577 NEPVFKQQLYTANIMEDALVGTSVSQVGATDAD---VGLNGRIHYELDPK--DREEGS-- 629 N P F Q +Y N+ E+ G+SV + A D D N ++ Y ++ + E G+ Sbjct: 418 NAPQFPQGIYFGNVTENGTAGSSVMTMSAVDYDDPNESTNAKLIYSIEKNVIEEETGAPI 477 Query: 630 FVIDPASGVIRTNK-ALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688 F I+P +G+I+T LDRE + ++ VA+DGG + T I+++D+ND PP F Sbjct: 478 FEIEPETGLIKTAVCCLDRERTPDYSIQVVAMDGGGLKGTGT--ASIRVKDLNDMPPQFT 535 Query: 689 SDCLTFYISENSPIGTTIGE-----IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 D + E + GT I E + D DE G ++ F++ R G Sbjct: 536 KDEWVTEVDETN--GTYIPETPILTVTVQDEDETNTFQYKVVPNSGFGADKFAM-VRNGD 592 Query: 744 DKAELVTMVDLDYESP------RKKYELVIRAASPPLWNDVR------VEILVTDVNDNA 791 L + LDYE P R + ++ + P +D V + + D+NDN Sbjct: 593 GTGSLKIIQPLDYEDPLQSSGFRFRIQVNDKGDDGPGGSDKYHVAYSWVVVKLRDINDNV 652 Query: 792 PVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSM 849 P I + Y+D + A DAD K+ Y+I+ N G++ Sbjct: 653 PKFDREHIEVSIYEDTKVGTILEQFKATDADQGGHSKVAYKIVRSTNRKRQFAISDRGAV 712 Query: 850 TLSPQLNTNVPKLATMEV-SVTDGVNEIKAMMQLSV 884 ++ L+ +++ ++ DG A L+V Sbjct: 713 SIQRPLDRETQDRHHIQILAIDDGSPARTATATLTV 748 Score = 103 bits (246), Expect = 9e-20 Identities = 88/299 (29%), Positives = 136/299 (45%), Gaps = 27/299 (9%) Query: 138 VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG-NT 196 V + D NDN P+F + VS+ ED V ++ + KATDAD G +S + Y I+ N Sbjct: 643 VKLRDINDNVPKFDREHIEVSIYEDTKV--GTILEQFKATDADQGGHSKVAYKIVRSTNR 700 Query: 197 QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256 + QF+I G VS+ + LD E + + I A D GSP+R+ T L + ++DVNDNAP Sbjct: 701 KRQFAISD-RGAVSIQRPLDRETQDRHHIQILAIDDGSPARTATATLTVIVKDVNDNAPT 759 Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADE---GVNAELTYTM----TDKDYTG-NVDLP 308 F ++ ++ ENV G I+ V A D D+ G T+ + +D+ G V+ Sbjct: 760 FAQD-YKPTLPENVS-GKKILEVAAKDPDDRLRGNGGPFTFRLDPLASDEIKAGFKVEYD 817 Query: 309 ITIDPRSGWVYTSG--QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 D +G S DRE Q Y + + D G P + T T Sbjct: 818 RRGDNENGVAIISSLRPFDREAQKSYAIPIEIKDNGAP--AMTGTSTLTVTIGDVNDNKM 875 Query: 367 MPGQYEVEL--AEDEPPGTPVVTLTATDADE----DNRLHYEITGGNTRGRFSITSQNG 419 PG V + + + TP+ + D D+ D + ++E+ RF + + G Sbjct: 876 QPGSKSVLVYNYQGQSQDTPIGRVYVNDPDDWDVPDKKYYWEV---QEHQRFKLDTDTG 931 Score = 77.4 bits (182), Expect = 5e-12 Identities = 52/142 (36%), Positives = 75/142 (52%), Gaps = 8/142 (5%) Query: 395 EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM 454 E + Y+ITGGN F++ QN G+I VA PLD++ RY L + AT + + T + Sbjct: 178 ESTNIRYQITGGNIGNAFAV--QNTTGVIYVASPLDYETRPRYELRLEATRNRKNNYTTV 235 Query: 455 VQINITDANNYAPVFENAPYTASVFE--DAPIGTTVLVVSATDSDVGINAQITYSLSSE- 511 V IN+ D N+ PVF+ Y + E D + +L V+ATD DV I Y L+ + Sbjct: 236 V-INVRDVNDNPPVFDRQTYRTQITEEDDRNLPKRILQVTATDGDVDRPINIVYFLTGQG 294 Query: 512 ISNEAVAHHDQQFVINPQTGAI 533 I + A + +F IN TG I Sbjct: 295 IDPDNPA--NSKFDINRTTGDI 314 Score = 60.1 bits (139), Expect = 9e-07 Identities = 38/115 (33%), Positives = 59/115 (51%), Gaps = 9/115 (7%) Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 IRY I GGN F++ + +G + + LDYE Y L + A ++N T ++IN Sbjct: 182 IRYQITGGNIGNAFAVQNTTGVIYVASPLDYETRPRYELRLEATRN---RKNNYTTVVIN 238 Query: 247 IRDVNDNAPRFYTSLFQESVSE----NVPIGYSIVRVQAYDADEGVNAELTYTMT 297 +RDVNDN P F ++ ++E N+P I++V A D D + Y +T Sbjct: 239 VRDVNDNPPVFDRQTYRTQITEEDDRNLP--KRILQVTATDGDVDRPINIVYFLT 291 Score = 53.6 bits (123), Expect = 8e-05 Identities = 42/166 (25%), Positives = 69/166 (41%), Gaps = 12/166 (7%) Query: 54 KNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARY 113 K AE T D L E + + F + +G + + LD E RY Sbjct: 159 KMAEQYDTFIKFNHDQLQRESTNIRYQITGGNIGNAFAVQNTTGVIYVASPLDYETRPRY 218 Query: 114 TVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK 173 + ++AT +R ++ T+ +N+ D NDN P F +TY + E+ I + Sbjct: 219 ELRLEAT------RNRKNNYTTVVINVRDVNDNPPVFDRQTYRTQITEEDDRNLPKRILQ 272 Query: 174 IKATDADVGANSAIRYAIIG------GNTQMQFSIDSLSGDVSLVK 213 + ATD DV I Y + G +F I+ +GD+ ++K Sbjct: 273 VTATDGDVDRPINIVYFLTGQGIDPDNPANSKFDINRTTGDIFVLK 318 Score = 52.0 bits (119), Expect = 2e-04 Identities = 46/128 (35%), Positives = 57/128 (44%), Gaps = 10/128 (7%) Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583 F + TG I LD ET Y L + A ++ T V I+V DVNDN PVF + Sbjct: 195 FAVQNTTGVIYVASPLDYETRPRYELRLEATRN---RKNNYTTVVINVRDVNDNPPVFDR 251 Query: 584 QLYTANIME--DALVGTSVSQVGATDADVGLNGRIHYEL-----DPKDREEGSFVIDPAS 636 Q Y I E D + + QV ATD DV I Y L DP + F I+ + Sbjct: 252 QTYRTQITEEDDRNLPKRILQVTATDGDVDRPINIVYFLTGQGIDPDNPANSKFDINRTT 311 Query: 637 GVIRTNKA 644 G I KA Sbjct: 312 GDIFVLKA 319 Score = 44.4 bits (100), Expect = 0.046 Identities = 29/82 (35%), Positives = 41/82 (50%), Gaps = 5/82 (6%) Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771 HD + + + Y I GG+ N+F+++ G + LDYE+ R +YEL + A Sbjct: 172 HDQLQRESTNIRYQITGGNIGNAFAVQNTTGV----IYVASPLDYET-RPRYELRLEATR 226 Query: 772 PPLWNDVRVEILVTDVNDNAPV 793 N V I V DVNDN PV Sbjct: 227 NRKNNYTTVVINVRDVNDNPPV 248 Score = 39.5 bits (88), Expect = 1.3 Identities = 23/91 (25%), Positives = 41/91 (45%), Gaps = 5/91 (5%) Query: 11 INVLDCNDHSPVFEMQQYEASVRE--GASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68 INV D ND+ PVF+ Q Y + E + +L + ATD D+ + + Y +T Sbjct: 237 INVRDVNDNPPVFDRQTYRTQITEEDDRNLPKRILQVTATDGDVDRPINIVY---FLTGQ 293 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL 99 ++P++ D+F + ++ L Sbjct: 294 GIDPDNPANSKFDINRTTGDIFVLKAKTKRL 324 Score = 38.7 bits (86), Expect = 2.3 Identities = 18/42 (42%), Positives = 24/42 (57%), Gaps = 3/42 (7%) Query: 1309 GCPEKRSRCSSAPCYNGAECSDLWD--TYICDCKEGHTGKDC 1348 GC + R+ C PC NGA C +L Y C C EG+ G++C Sbjct: 1690 GCVD-RNECLDLPCLNGATCINLEPRLRYRCICPEGYWGENC 1730 Score = 37.9 bits (84), Expect = 4.0 Identities = 28/109 (25%), Positives = 54/109 (49%), Gaps = 6/109 (5%) Query: 629 SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688 +F + +GVI LD E+ ++L+ A +TV+++++ D+ND+PPVF+ Sbjct: 194 AFAVQNTTGVIYVASPLDYETRPRYELRLEATRN-RKNNYTTVVINVR--DVNDNPPVFD 250 Query: 689 SDCLTFYISENSP--IGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNS 734 I+E + I ++ A D D + P +V++ G D ++ Sbjct: 251 RQTYRTQITEEDDRNLPKRILQVTATDGDVDRPINIVYFLTGQGIDPDN 299 >UniRef50_A4KCK1 Cluster: Protocadherin 2A37; n=12; Clupeocephala|Rep: Protocadherin 2A37 - Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) Length = 1013 Score = 237 bits (579), Expect = 4e-60 Identities = 183/627 (29%), Positives = 289/627 (46%), Gaps = 29/627 (4%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F I+ ++G L +DRE + +T + V + + V I+D NDN PQ Sbjct: 78 FAINHKNGKLTVSDRIDRETICEFTGTCSLNLEV--VLENPLDVHNVEVEILDVNDNAPQ 135 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG-- 207 F Y + V E ++T + A DAD G+NS +Y + + S+ S Sbjct: 136 FPRDEYQLEVSES-ALTGTRFHIE-GAQDADDGSNSVKQYRLSRNDHLTLDSVKQFSNNK 193 Query: 208 --DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265 ++ L K D E + S+ L++ A DGG+P RS T ++ + I D NDNAP F +S+++ Sbjct: 194 HIELILKKPFDRELMPSHELILTAIDGGTPQRSGTARINVRILDANDNAPVFGSSVYKVK 253 Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT-GNVDLPITIDPRSGWVYTSGQL 324 +SEN P G ++++ A D DEG N ++ Y+ + YT V ++D +G + + Sbjct: 254 LSENSPKGALVIKLNAADIDEGSNGDVFYSFS--SYTPERVRQMFSLDTDTGEIRVKNNI 311 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 D E Y++ + A D G P +A + + ED T Sbjct: 312 DYEETNSYEMYIQAMDKGPAPVAANCKVVVDILDVNDNVPEIVLSSLSSPVREDARADTV 371 Query: 385 VVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 V ++ D D ++ ++ EI G N F+I S I + LD + + Y +TVS Sbjct: 372 VALISVNDRDSGQNKQVTLEI-GPNL--PFAIKSFRNHYTIVTSAFLDRETIKSYNVTVS 428 Query: 443 ATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 A D G S +++ D N+ P FE YT V E+ G ++ VV ATD+D Sbjct: 429 AVDGGTPPLSSQMSFMVDVADVNDNPPRFEQTSYTVYVTENNAPGASLCVVRATDADAAE 488 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560 NA+ITY++ S+ N I P TG + D E + + V A+D GVP Sbjct: 489 NARITYTVISD--NNYGIPVASYVSIKPNTGEAYALRAFDFEKLREFHFQVKAQDNGVPP 546 Query: 561 LSDTTDVEISVVDVNDNEP-VF----KQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615 LS V + ++D ND+ P +F L T +M++A G VS+V A D D G N Sbjct: 547 LSRVVTVYLYIMDQNDHVPKIFYPPTNGSLTTEMLMKNAEAGVLVSKVVAWDGDAGQNAW 606 Query: 616 IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675 + Y L + + F + +G IRT + + ++ + L + D G PP S+T +HI Sbjct: 607 LMYTLKQTNTDLDLFKVHEYTGEIRTTRHVIEDNSTSFVLTVLVRDHGLPPLSTTATLHI 666 Query: 676 KIEDINDSPPVFESDCLTFYISENSPI 702 + ++ PP D I NSP+ Sbjct: 667 HVMEL---PPKMTPDPKRI-IRPNSPL 689 Score = 215 bits (524), Expect = 2e-53 Identities = 156/500 (31%), Positives = 230/500 (46%), Gaps = 28/500 (5%) Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + I DVNDNAP+F +Q VSE+ G A DAD+G N+ Y ++ D+ Sbjct: 124 VEILDVNDNAPQFPRDEYQLEVSESALTGTRFHIEGAQDADDGSNSVKQYRLSRNDHLTL 183 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 + + + + DRE ++L++TA DGG P RS TA Sbjct: 184 DSVKQFSNNKHIELILKKPFDRELMPSHELILTAIDGGTPQRSGTARINVRILDANDNAP 243 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEI---TGGNTRGRFSITSQNG 419 F Y+V+L+E+ P G V+ L A D DE + + Y T R FS+ + G Sbjct: 244 VFGSSVYKVKLSENSPKGALVIKLNAADIDEGSNGDVFYSFSSYTPERVRQMFSLDTDTG 303 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTAS 477 I V +D+++ Y + + A D G A V ++I D N+ P + ++ Sbjct: 304 E--IRVKNNIDYEETNSYEMYIQAMDKGPAPVAANCKVVVDILDVNDNVPEIVLSSLSSP 361 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 V EDA T V ++S D D G N Q+T + + + + ++ T+ Sbjct: 362 VREDARADTVVALISVNDRDSGQNKQVTLEIGPNLPFAIKSFRNHYTIV--------TSA 413 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LDRET+ Y +TV+A DGG P LS + V DVNDN P F+Q YT + E+ G Sbjct: 414 FLDRETIKSYNVTVSAVDGGTPPLSSQMSFMVDVADVNDNPPRFEQTSYTVYVTENNAPG 473 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEG----SFV-IDPASGVIRTNKALDRESVAT 652 S+ V ATDAD N RI Y + D G S+V I P +G +A D E + Sbjct: 474 ASLCVVRATDADAAENARITYTV-ISDNNYGIPVASYVSIKPNTGEAYALRAFDFEKLRE 532 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDS-PPVF----ESDCLTFYISENSPIGTTIG 707 + A D G PP S V V++ I D ND P +F T + +N+ G + Sbjct: 533 FHFQVKAQDNGVPPLSRVVTVYLYIMDQNDHVPKIFYPPTNGSLTTEMLMKNAEAGVLVS 592 Query: 708 EIRAHDPDEGPNAVVHYSIK 727 ++ A D D G NA + Y++K Sbjct: 593 KVVAWDGDAGQNAWLMYTLK 612 Score = 207 bits (506), Expect = 3e-51 Identities = 160/587 (27%), Positives = 260/587 (44%), Gaps = 47/587 (8%) Query: 4 PFCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 P +H ++ +LD ND++P F +Y+ V E A +GT A D D G N+ +Y Sbjct: 116 PLDVHNVEVEILDVNDNAPQFPRDEYQLEVSESALTGTRFHIEGAQDADDGSNSVKQY-- 173 Query: 63 ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122 L D L + + + L+ + DRE + + +++ A D Sbjct: 174 RLSRNDHLTLDSVKQFS-------------NNKHIELILKKPFDRELMPSHELILTAIDG 220 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 +P + S TA I+V I+D NDN P F Y V + E + ++ K+ A D D G Sbjct: 221 GTP---QRSGTARINVRILDANDNAPVFGSSVYKVKLSE--NSPKGALVIKLNAADIDEG 275 Query: 183 ANSAIRYAIIG---GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239 +N + Y+ + FS+D+ +G++ + +DYE+ SY + I+A D G + Sbjct: 276 SNGDVFYSFSSYTPERVRQMFSLDTDTGEIRVKNNIDYEETNSYEMYIQAMDKGPAPVAA 335 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 +++++I DVNDN P S V E+ + + D D G N ++T Sbjct: 336 NCKVVVDILDVNDNVPEIVLSSLSSPVREDARADTVVALISVNDRDSGQNKQVTL----- 390 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 + N+ I + TS LDRET Y + V+A DGG PP S+ + Sbjct: 391 EIGPNLPFAIKSFRNHYTIVTSAFLDRETIKSYNVTVSAVDGGTPPLSSQMSFMVDVADV 450 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRG---RFSI 414 F Y V + E+ PG + + ATDAD E+ R+ Y + N G + Sbjct: 451 NDNPPRFEQTSYTVYVTENNAPGASLCVVRATDADAAENARITYTVISDNNYGIPVASYV 510 Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENA 472 + + G + DF++ R + V A D+G S V + I D N++ P Sbjct: 511 SIKPNTGEAYALRAFDFEKLREFHFQVKAQDNGVPPLSRVVTVYLYIMDQNDHVPKIFYP 570 Query: 473 PYTAS-----VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527 P S + ++A G V V A D D G NA + Y+L +N + F ++ Sbjct: 571 PTNGSLTTEMLMKNAEAGVLVSKVVAWDGDAGQNAWLMYTLKQ--TNTDL----DLFKVH 624 Query: 528 PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 TG I T + + + + ++LTV RD G+P LS T + I V+++ Sbjct: 625 EYTGEIRTTRHVIEDNSTSFVLTVLVRDHGLPPLSTTATLHIHVMEL 671 Score = 180 bits (438), Expect = 5e-43 Identities = 128/440 (29%), Positives = 214/440 (48%), Gaps = 23/440 (5%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRL--HYEITGGNTRGRFSIT--SQNGRG 421 F +Y++E++E GT A DAD+ + Y ++ + S+ S N Sbjct: 136 FPRDEYQLEVSESALTGTRFHIEGAQDADDGSNSVKQYRLSRNDHLTLDSVKQFSNNKHI 195 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVF 479 + + +P D + + L ++A D G RS TA + + I DAN+ APVF ++ Y + Sbjct: 196 ELILKKPFDRELMPSHELILTAIDGGTPQRSGTARINVRILDANDNAPVFGSSVYKVKLS 255 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E++P G V+ ++A D D G N + YS SS + E V Q F ++ TG I + Sbjct: 256 ENSPKGALVIKLNAADIDEGSNGDVFYSFSS-YTPERVR---QMFSLDTDTGEIRVKNNI 311 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 D E + Y + + A D G ++ V + ++DVNDN P ++ + EDA T Sbjct: 312 DYEETNSYEMYIQAMDKGPAPVAANCKVVVDILDVNDNVPEIVLSSLSSPVREDARADTV 371 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG--VIRTNKALDRESVATHDLKA 657 V+ + D D G N ++ E+ P F I I T+ LDRE++ ++++ Sbjct: 372 VALISVNDRDSGQNKQVTLEIGPNL----PFAIKSFRNHYTIVTSAFLDRETIKSYNVTV 427 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A+DGGTPP SS + + + D+ND+PP FE T Y++EN+ G ++ +RA D D Sbjct: 428 SAVDGGTPPLSSQMSFMVDVADVNDNPPRFEQTSYTVYVTENNAPGASLCVVRATDADAA 487 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQG--SDKAELVTMVDLDYESPRKKYELVIRAAS---P 772 NA + Y++ D++ + + + E + D+E R+ + ++A P Sbjct: 488 ENARITYTVIS-DNNYGIPVASYVSIKPNTGEAYALRAFDFEKLRE-FHFQVKAQDNGVP 545 Query: 773 PLWNDVRVEILVTDVNDNAP 792 PL V V + + D ND+ P Sbjct: 546 PLSRVVTVYLYIMDQNDHVP 565 Score = 159 bits (386), Expect = 1e-36 Identities = 134/474 (28%), Positives = 210/474 (44%), Gaps = 23/474 (4%) Query: 374 ELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGR-FSITSQNGRGLITVAQPLDFK 432 EL P G V L D + + +T T R F+I +NG+ +TV+ +D + Sbjct: 40 ELENGAPVGDIVQDL-GLDPRKLSARRIRVTSDGTHRRYFAINHKNGK--LTVSDRIDRE 96 Query: 433 QERRYVLTVSATDS---GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 + T S D V++ I D N+ AP F Y V E A GT Sbjct: 97 TICEFTGTCSLNLEVVLENPLDVHNVEVEILDVNDNAPQFPRDEYQLEVSESALTGTRFH 156 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 + A D+D G N+ Y LS ++ +QF N I K DRE M + L Sbjct: 157 IEGAQDADDGSNSVKQYRLSR--NDHLTLDSVKQFSNNKHIELIL-KKPFDRELMPSHEL 213 Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 +TA DGG P S T + + ++D NDN PVF +Y + E++ G V ++ A D D Sbjct: 214 ILTAIDGGTPQRSGTARINVRILDANDNAPVFGSSVYKVKLSENSPKGALVIKLNAADID 273 Query: 610 VGLNGRIHYELDP--KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 G NG + Y +R F +D +G IR +D E ++++ A+D G P Sbjct: 274 EGSNGDVFYSFSSYTPERVRQMFSLDTDTGEIRVKNNIDYEETNSYEMYIQAMDKGPAPV 333 Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 ++ V + I D+ND+ P L+ + E++ T + I +D D G N V I Sbjct: 334 AANCKVVVDILDVNDNVPEIVLSSLSSPVREDARADTVVALISVNDRDSGQNKQVTLEI- 392 Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILV 784 + F++++ + + +VT LD E+ K Y + + A +PPL + + + V Sbjct: 393 --GPNLPFAIKSFR--NHYTIVTSAFLDRETI-KSYNVTVSAVDGGTPPLSSQMSFMVDV 447 Query: 785 TDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGNN 836 DVNDN P + ++ P V A DAD + ++ Y ++S NN Sbjct: 448 ADVNDNPPRFEQTSYTVYVTENNAPGASLCVVRATDADAAENARITYTVISDNN 501 >UniRef50_Q7PT49 Cluster: ENSANGP00000019477; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000019477 - Anopheles gambiae str. PEST Length = 976 Score = 235 bits (574), Expect = 2e-59 Identities = 242/811 (29%), Positives = 367/811 (45%), Gaps = 82/811 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I VLD ND PVF + ++ E GT V+ ++A D D G A I D Sbjct: 218 KIKVLDENDIIPVFT-EVTSGTIPEDEPPGTPVMQVRAYDLD-GTPAN---NIVSYRFDD 272 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N Q +F ID R+G + +R DRE Y + + A D SP + Sbjct: 273 EN---------------QQLFHIDSRTGNITSRVEFDREATDSYHLKIIAEDN-SPSA-- 314 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTV-SVDEDISVTDNPVIAKIKATDADVGANSAIR 188 L S I + I D ND+ P+F + + +V ED ++ N V+ ++ A D D S I Sbjct: 315 LISQLFI-IKISDKNDHQPKFVKDHFVAENVPEDANI--NTVVIEVTALDQDTA--SLIT 369 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y+II GN F ID +G +S+ LDYE +R Y L+++A DG + N T + I I Sbjct: 370 YSIIEGNVGDAFKIDENTGRISVNSRLDYETIREYMLIVQADDG--IFQDNAT-VSIKIE 426 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYD-----ADEGVNAELTYTMTDKDYT- 302 +VNDN PRF E +P G I+ +QAYD DE + ++ DK + Sbjct: 427 NVNDNPPRFIDLRNVTIQEETIPPG-CIMTIQAYDPDIENRDEPQHIRFSFEAVDKSGSI 485 Query: 303 --GNVDLPITIDPRSGWVYTSG---QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357 NV + G + T Q + V ATD G P T Sbjct: 486 RFHNVTAEEFVSRTPGQLTTPKDRLQASIANTLNIYITVRATDNGRPRLDDVCTFKVMIL 545 Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DNR-LHYEITGGNTRGRFSIT 415 F +YE + +D V T++ATD D+ DN + YEI N + Sbjct: 546 DINDNPPVFDKVRYEESVTKDMKANLRVATISATDMDDGDNSIIKYEIVQQNPDSSYFKI 605 Query: 416 SQNGRGLITVAQP-LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPY 474 ++N GL+T+ +P LD++ Y LTVS +S +++I + D N+ PVF Sbjct: 606 NEN-NGLLTLTKPTLDYETVTEYTLTVSVKNSYNNVVETVLKIKVLDENDIIPVFTEVT- 663 Query: 475 TASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 + ++ E+ P GT V+ V A D D N ++Y + E + Q F I+ +TG+I Sbjct: 664 SGTIPENEPPGTPVMQVRAYDLDGTPANNIVSYRIEDE--------NQQLFHIDSRTGSI 715 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSL-------SDTTDVEISVVDVNDNEPVF-KQQL 585 T+ DRE Y L + A D +L S + I + D ND++P F K L Sbjct: 716 TSRVEFDREATDSYHLKIIAEDNSPSALYSNGKPNSCSQLFTIKISDKNDHKPRFVKGLL 775 Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645 T ++ ED+ + ++ +V A D D I Y + + +F ID +G I N L Sbjct: 776 ATEDVSEDSDINMTLIEVKALDQDTA--SLITYSI-IEGNVGDAFKIDEHTGRISINNWL 832 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT- 704 D E++ + L V D G S+T V+IKI+++ND+PP F E P G Sbjct: 833 DYETIREYKL-IVQADDGIFQDSTT--VYIKIKNVNDNPPRFTGIRNVTIQEETIPSGPP 889 Query: 705 -TIGEIRAHDPDEGPNA-VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK 762 I + A D DE N H+SI D + + ++ R EL +V+ D E +K+ Sbjct: 890 GLIVRLTAEDVDEAQNGPPFHFSI---DPNAPYEIKERFQVQNDELYALVEFDREE-QKE 945 Query: 763 YELVIR---AASPPLWNDVRVEILVTDVNDN 790 Y + IR + P+ + +++++ D NDN Sbjct: 946 YRVPIRISDSGEEPMSDVSILQLVIGDDNDN 976 Score = 226 bits (553), Expect = 6e-57 Identities = 236/903 (26%), Positives = 401/903 (44%), Gaps = 91/903 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ +LD ND+ PVF+ +YE SV + + V T+ ATD D G N+ ++Y E+V Sbjct: 32 KVTILDINDNPPVFDKVRYEESVTKDMKANLRVATISATDMDDGDNSIIKY--EIVQQ-- 87 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 NP+ + F+I+ +G L +DR Y++ V+A + Sbjct: 88 -NPDSSY-------------FKINENNGLLTLTKPVDRSPGQYYSIRVRAYN-------- 125 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 +D Q +E V V E + P K++A A + N + Sbjct: 126 -----------VDPQGEAVQDAEVDVKVRVVESNKLP--PYFTKVQA--AALVLNETFK- 169 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 T+ ++ S +TLDYE V Y L + ++ S T L I + D Sbjct: 170 ----NYTESLAEFEAESNIPEKPETLDYETVTEYTLTVSVKN--SHDLVAETVLKIKVLD 223 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYTGNVDLP 308 ND P F T + ++ E+ P G +++V+AYD D N ++Y D+ N L Sbjct: 224 ENDIIPVF-TEVTSGTIPEDEPPGTPVMQVRAYDLDGTPANNIVSYRFDDE----NQQL- 277 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 ID R+G + + + DRE Y L + A D P + F+ Sbjct: 278 FHIDSRTGNITSRVEFDREATDSYHLKIIAEDNS-PSALISQLFIIKISDKNDHQPKFVK 336 Query: 369 GQYEVE-LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 + E + ED T V+ +TA D D + + Y I GN F I GR I+V Sbjct: 337 DHFVAENVPEDANINTVVIEVTALDQDTASLITYSIIEGNVGDAFKIDENTGR--ISVNS 394 Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 LD++ R Y+L V A D G D A V I I + N+ P F + E P G Sbjct: 395 RLDYETIREYMLIVQA-DDGIFQDNATVSIKIENVNDNPPRFIDLRNVTIQEETIPPGC- 452 Query: 488 VLVVSATDSDVGINAQ---ITYSLSSEISNEAVAHHD---QQFVINPQTGAITTNKLLDR 541 ++ + A D D+ + I +S + + ++ H+ ++FV + G +TT K + Sbjct: 453 IMTIQAYDPDIENRDEPQHIRFSFEAVDKSGSIRFHNVTAEEFV-SRTPGQLTTPKDRLQ 511 Query: 542 ETMSGYL---LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 +++ L +TV A D G P L D ++ ++D+NDN PVF + Y ++ +D Sbjct: 512 ASIANTLNIYITVRATDNGRPRLDDVCTFKVMILDINDNPPVFDKVRYEESVTKDMKANL 571 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR-TNKALDRESVATHDLKA 657 V+ + ATD D G N I YE+ ++ + F I+ +G++ T LD E+V + L Sbjct: 572 RVATISATDMDDGDNSIIKYEIVQQNPDSSYFKINENNGLLTLTKPTLDYETVTEYTL-T 630 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 V++ TV+ IK+ D ND PVF ++ + I EN P GT + ++RA+D D Sbjct: 631 VSVKNSYNNVVETVL-KIKVLDENDIIPVF-TEVTSGTIPENEPPGTPVMQVRAYDLDGT 688 Query: 718 P-NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP--L 774 P N +V Y I+ ++ F +++R GS + + V+ D E+ + +I + P L Sbjct: 689 PANNIVSYRIE-DENQQLFHIDSRTGS----ITSRVEFDREATDSYHLKIIAEDNSPSAL 743 Query: 775 WNDVR-------VEILVTDVNDNAP-VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK 826 +++ + I ++D ND+ P +K + +D V A D D Sbjct: 744 YSNGKPNSCSQLFTIKISDKNDHKPRFVKGLLATEDVSEDSDINMTLIEVKALDQDTASL 803 Query: 827 LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRL 886 + Y I+ GN + ++E TG ++++ L+ + + V DG+ + + + ++ Sbjct: 804 ITYSIIEGNVGDAFKIDEHTGRISINNWLDYETIREYKLIVQADDGIFQDSTTVYIKIKN 863 Query: 887 ITE 889 + + Sbjct: 864 VND 866 Score = 226 bits (552), Expect = 8e-57 Identities = 223/754 (29%), Positives = 351/754 (46%), Gaps = 68/754 (9%) Query: 104 SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI 163 +LD E V YT+ V + S L + + + ++D+ND P F+E T + ++ ED Sbjct: 190 TLDYETVTEYTLTVSVKN-----SHDLVAETVLKIKVLDENDIIPVFTEVT-SGTIPED- 242 Query: 164 SVTDNPVIAKIKATDAD-VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222 PV+ +++A D D AN+ + Y N Q+ F IDS +G+++ D E S Sbjct: 243 EPPGTPVM-QVRAYDLDGTPANNIVSYRFDDENQQL-FHIDSRTGNITSRVEFDREATDS 300 Query: 223 YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLF-QESVSENVPIGYSIVRVQA 281 Y L I A+D SPS + +I I D ND+ P+F F E+V E+ I ++ V A Sbjct: 301 YHLKIIAEDN-SPSALISQLFIIKISDKNDHQPKFVKDHFVAENVPEDANINTVVIEVTA 359 Query: 282 YDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341 D D + +TY++ + GNV ID +G + + +LD ET +Y L+V A DG Sbjct: 360 LDQDTA--SLITYSIIE----GNVGDAFKIDENTGRISVNSRLDYETIREYMLIVQADDG 413 Query: 342 GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--- 398 AT F+ + E PPG ++T+ A D D +NR Sbjct: 414 ---IFQDNATVSIKIENVNDNPPRFIDLRNVTIQEETIPPGC-IMTIQAYDPDIENRDEP 469 Query: 399 ----LHYEITGGNTRGRF-SITSQN--GRGLITVAQPLDFKQER-----RYVLTVSATDS 446 +E + RF ++T++ R + P D Q +TV ATD+ Sbjct: 470 QHIRFSFEAVDKSGSIRFHNVTAEEFVSRTPGQLTTPKDRLQASIANTLNIYITVRATDN 529 Query: 447 GGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504 G D ++ I D N+ PVF+ Y SV +D V +SATD D G N+ I Sbjct: 530 GRPRLDDVCTFKVMILDINDNPPVFDKVRYEESVTKDMKANLRVATISATDMDDGDNSII 589 Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTGAITTNK-LLDRETMSGYLLTVTARDGGVPSLSD 563 Y + + + + F IN G +T K LD ET++ Y LTV+ ++ ++ + Sbjct: 590 KYEIVQQNPDSSY------FKINENNGLLTLTKPTLDYETVTEYTLTVSVKNS-YNNVVE 642 Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDP 622 T ++I V+D ND PVF + + + I E+ GT V QV A D D N + Y ++ Sbjct: 643 TV-LKIKVLDENDIIPVFTE-VTSGTIPENEPPGTPVMQVRAYDLDGTPANNIVSYRIE- 699 Query: 623 KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP-------PQSSTVIVHI 675 D + F ID +G I + DRE+ ++ LK +A D P S + + I Sbjct: 700 -DENQQLFHIDSRTGSITSRVEFDREATDSYHLKIIAEDNSPSALYSNGKPNSCSQLFTI 758 Query: 676 KIEDINDSPPVFESDCL-TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734 KI D ND P F L T +SE+S I T+ E++A D D +++ YSI G+ ++ Sbjct: 759 KISDKNDHKPRFVKGLLATEDVSEDSDINMTLIEVKALDQDTA--SLITYSIIEGNVGDA 816 Query: 735 FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVM 794 F ++ G + LDYE+ R+ Y+L+++A + V I + +VNDN P Sbjct: 817 FKIDEHTG----RISINNWLDYETIRE-YKLIVQADDGIFQDSTTVYIKIKNVNDNPPRF 871 Query: 795 KDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQ 828 + + ++ P GP G + A+ D+ Q Sbjct: 872 TGIRNV-TIQEETIPSGPPGLIVRLTAEDVDEAQ 904 Score = 178 bits (434), Expect = 2e-42 Identities = 216/767 (28%), Positives = 322/767 (41%), Gaps = 94/767 (12%) Query: 115 VLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKI 174 + V+ATD P RL T V I+D NDN P F + Y SV +D+ N +A I Sbjct: 13 ITVRATDNGRP---RLDDVCTFKVTILDINDNPPVFDKVRYEESVTKDMKA--NLRVATI 67 Query: 175 KATDADVGANSAIRYAIIGGNTQMQ-FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233 ATD D G NS I+Y I+ N F I+ +G ++L K +D + Y + +RA + Sbjct: 68 SATDMDDGDNSIIKYEIVQQNPDSSYFKINENNGLLTLTKPVDRSPGQYYSIRVRAYNVD 127 Query: 234 SPSRS-NTTQLLINIRDVNDN-APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE 291 + ++ + +R V N P ++T +VQA A Sbjct: 128 PQGEAVQDAEVDVKVRVVESNKLPPYFT------------------KVQA--------AA 161 Query: 292 LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 L T K+YT ++ + S LD ET +Y L V+ + D T Sbjct: 162 LVLNETFKNYTESL---AEFEAESNIPEKPETLDYETVTEYTLTVSVKNSHD---LVAET 215 Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNT 408 + EDEPPGTPV+ + A D D +N + Y N Sbjct: 216 VLKIKVLDENDIIPVFTEVTSGTIPEDEPPGTPVMQVRAYDLDGTPANNIVSYRFDDENQ 275 Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD-SGGRSDTAMVQINITDANNYAP 467 + F I S+ G IT D + Y L + A D S + + I I+D N++ P Sbjct: 276 Q-LFHIDSRTGN--ITSRVEFDREATDSYHLKIIAEDNSPSALISQLFIIKISDKNDHQP 332 Query: 468 VFENAPYTA-SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 F + A +V EDA I T V+ V+A D D + ITYS+ +A F I Sbjct: 333 KFVKDHFVAENVPEDANINTVVIEVTALDQDTA--SLITYSIIEGNVGDA-------FKI 383 Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586 + TG I+ N LD ET+ Y+L V A DG D V I + +VNDN P F L Sbjct: 384 DENTGRISVNSRLDYETIREYMLIVQADDG---IFQDNATVSIKIENVNDNPPRF-IDLR 439 Query: 587 TANIMEDALVGTSVSQVGATDADVGLNG---RIHYELDPKDREEGSF---------VIDP 634 I E+ + + + A D D+ I + + D+ GS + Sbjct: 440 NVTIQEETIPPGCIMTIQAYDPDIENRDEPQHIRFSFEAVDK-SGSIRFHNVTAEEFVSR 498 Query: 635 ASGVIRTNKALDRESVATH---DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691 G + T K + S+A + A D G P + I DIND+PPVF+ Sbjct: 499 TPGQLTTPKDRLQASIANTLNIYITVRATDNGRPRLDDVCTFKVMILDINDNPPVFDKVR 558 Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-KGGDDSNSFSLETRQGSDKAELVT 750 ++++ + I A D D+G N+++ Y I + DS+ F + G +T Sbjct: 559 YEESVTKDMKANLRVATISATDMDDGDNSIIKYEIVQQNPDSSYFKINENNG---LLTLT 615 Query: 751 MVDLDYESPRKKYELVIRAASPPLWNDV---RVEILVTDVNDNAPVMKDFQIIFNNYKDC 807 LDYE+ +Y L + + +N+V ++I V D ND PV ++ + Sbjct: 616 KPTLDYETV-TEYTLTVSVKNS--YNNVVETVLKIKVLDENDIIPVFT--EVTSGTIPEN 670 Query: 808 FPVG-PFGRVPAYDADVT---DKLQYRILSGNNANLILLNETTGSMT 850 P G P +V AYD D T + + YRI N L ++ TGS+T Sbjct: 671 EPPGTPVMQVRAYDLDGTPANNIVSYRI-EDENQQLFHIDSRTGSIT 716 Score = 65.7 bits (153), Expect = 2e-08 Identities = 49/166 (29%), Positives = 76/166 (45%), Gaps = 11/166 (6%) Query: 433 QERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 +E+ +TV ATD+G D ++ I D N+ PVF+ Y SV +D V Sbjct: 7 REKEIYITVRATDNGRPRLDDVCTFKVTILDINDNPPVFDKVRYEESVTKDMKANLRVAT 66 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550 +SATD D G N+ I Y + + + + F IN G +T K +DR Y + Sbjct: 67 ISATDMDDGDNSIIKYEIVQQNPDSS------YFKINENNGLLTLTKPVDRSPGQYYSIR 120 Query: 551 VTAR--DGGVPSLSDT-TDVEISVVDVNDNEPVFKQQLYTANIMED 593 V A D ++ D DV++ VV+ N P F + A ++ + Sbjct: 121 VRAYNVDPQGEAVQDAEVDVKVRVVESNKLPPYFTKVQAAALVLNE 166 >UniRef50_Q17NI9 Cluster: Protocadherin; n=3; Endopterygota|Rep: Protocadherin - Aedes aegypti (Yellowfever mosquito) Length = 605 Score = 234 bits (573), Expect = 2e-59 Identities = 173/533 (32%), Positives = 258/533 (48%), Gaps = 45/533 (8%) Query: 92 IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151 ID +G + T+ LDREK A Y+++ A P+S + + ++D+NDN P F Sbjct: 95 IDHTTGEIRTKVLLDREKRASYSLV------AIPLS---GENVRVVIRVLDENDNAPTFP 145 Query: 152 EKTYTVSVDE----DISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS--- 204 + E D+ T NP A D D+G + RY I+ GN F + S Sbjct: 146 TALMNIEFPENTPRDVKRTLNP------ARDLDLGRYNTQRYNIVSGNVNNAFRLSSHRE 199 Query: 205 ----LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260 L D+ + LD E +Y LV+ A DGG+P + I I+DVNDN P F S Sbjct: 200 RDGVLYLDLQINGFLDRETTPAYSLVVEALDGGNPPLRGQMTVNITIQDVNDNQPIFNQS 259 Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT 320 + +V EN IG ++++V A D D G N + Y + + + D IDP +G + Sbjct: 260 RYFATVPENATIGTTVLQVYATDQDAGENGMVEYAINRRQ--SDKDQMFRIDPNTGLISV 317 Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX----XXFMPGQYEVELA 376 + LD ET+ ++L+V A D G P TA F+ +++ Sbjct: 318 NKPLDFETKELHELVVVAKDRGLQPLETTAFVSIRVTDVNDNQPIINVIFLSDDATPKIS 377 Query: 377 EDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQ-NGRGLITVAQPLDFK 432 E PG V ++ D D E + ++ ++GG G F +T++ N L+ V+ PLD + Sbjct: 378 ESAQPGEFVARISVNDPDSKTEYSNVNVTLSGGE--GHFGLTTRDNIIYLVIVSLPLDRE 435 Query: 433 QERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 + Y L+V ATD+G A + + +TD N+ AP FE Y A+V E A GT+V+ Sbjct: 436 IKPNYTLSVVATDTGNPPLHAAKTIFLTVTDINDNAPEFEKEIYHANVMEVADPGTSVIQ 495 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550 V+A D D G N+ I YSL H Q F I+ +G ITT +D ET L Sbjct: 496 VTAIDKDEGNNSAIAYSLLDTPDT-----HSQWFQIDSNSGLITTRAHIDCETDPVPQLI 550 Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 V A+D G P +S T V +++ DVNDNEP+F Q Y ++ E+ G + +V Sbjct: 551 VVAKDNGFPPMSSTGTVLVTIHDVNDNEPIFDQSFYNVSVAENEPKGRCILKV 603 Score = 221 bits (541), Expect = 2e-55 Identities = 174/545 (31%), Positives = 242/545 (44%), Gaps = 36/545 (6%) Query: 182 GANSAIRYAII---GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238 G +S Y I+ G +ID +G++ LD E+ SY LV P Sbjct: 72 GVDSGPPYLIVPVPGSAVDTDLAIDHTTGEIRTKVLLDREKRASYSLV------AIPLSG 125 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 +++I + D NDNAP F T+L EN P A D D G Y + Sbjct: 126 ENVRVVIRVLDENDNAPTFPTALMNIEFPENTPRDVKRTLNPARDLDLGRYNTQRYNIV- 184 Query: 299 KDYTGNVDLPITIDP---RSGWVYT----SGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 +GNV+ + R G +Y +G LDRET Y L+V A DGG+PP T Sbjct: 185 ---SGNVNNAFRLSSHRERDGVLYLDLQINGFLDRETTPAYSLVVEALDGGNPPLRGQMT 241 Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTR 409 F +Y + E+ GT V+ + ATD D E+ + Y I + Sbjct: 242 VNITIQDVNDNQPIFNQSRYFATVPENATIGTTVLQVYATDQDAGENGMVEYAINRRQSD 301 Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAP 467 GLI+V +PLDF+ + + L V A D G + TA V I +TD N+ P Sbjct: 302 KDQMFRIDPNTGLISVNKPLDFETKELHELVVVAKDRGLQPLETTAFVSIRVTDVNDNQP 361 Query: 468 V----FENAPYTASVFEDAPIGTTVLVVSATDSDVGIN-AQITYSLSSEISNEAVAHHDQ 522 + F + T + E A G V +S D D + + +LS + + D Sbjct: 362 IINVIFLSDDATPKISESAQPGEFVARISVNDPDSKTEYSNVNVTLSGGEGHFGLTTRDN 421 Query: 523 QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582 + + + LDRE Y L+V A D G P L + ++V D+NDN P F+ Sbjct: 422 IIYL------VIVSLPLDREIKPNYTLSVVATDTGNPPLHAAKTIFLTVTDINDNAPEFE 475 Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGVIRT 641 +++Y AN+ME A GTSV QV A D D G N I Y LD D F ID SG+I T Sbjct: 476 KEIYHANVMEVADPGTSVIQVTAIDKDEGNNSAIAYSLLDTPDTHSQWFQIDSNSGLITT 535 Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701 +D E+ L VA D G PP SST V + I D+ND+ P+F+ ++EN P Sbjct: 536 RAHIDCETDPVPQLIVVAKDNGFPPMSSTGTVLVTIHDVNDNEPIFDQSFYNVSVAENEP 595 Query: 702 IGTTI 706 G I Sbjct: 596 KGRCI 600 Score = 206 bits (503), Expect = 7e-51 Identities = 164/546 (30%), Positives = 246/546 (45%), Gaps = 36/546 (6%) Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325 VSE VPIG+ I + + GV++ Y + + VD + ID +G + T LD Sbjct: 53 VSEGVPIGHQIGFIGEFL--HGVDSGPPYLIVPVPGSA-VDTDLAIDHTTGEIRTKVLLD 109 Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 RE +A Y L+ G + F +E E+ P Sbjct: 110 REKRASYSLVAIPLSGEN------VRVVIRVLDENDNAPTFPTALMNIEFPENTPRDVKR 163 Query: 386 VTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGR-GLITVAQP----LDFKQERRYV 438 A D D N Y I GN F ++S R G++ + LD + Y Sbjct: 164 TLNPARDLDLGRYNTQRYNIVSGNVNNAFRLSSHRERDGVLYLDLQINGFLDRETTPAYS 223 Query: 439 LTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496 L V A D G + +NIT D N+ P+F + Y A+V E+A IGTTVL V ATD Sbjct: 224 LVVEALDGGNPPLRGQMTVNITIQDVNDNQPIFNQSRYFATVPENATIGTTVLQVYATDQ 283 Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556 D G N + Y+++ S++ DQ F I+P TG I+ NK LD ET + L V A+D Sbjct: 284 DAGENGMVEYAINRRQSDK-----DQMFRIDPNTGLISVNKPLDFETKELHELVVVAKDR 338 Query: 557 GVPSLSDTTDVEISVVDVNDNEPV----FKQQLYTANIMEDALVGTSVSQVGATDADVGL 612 G+ L T V I V DVNDN+P+ F T I E A G V+++ D D Sbjct: 339 GLQPLETTAFVSIRVTDVNDNQPIINVIFLSDDATPKISESAQPGEFVARISVNDPDSKT 398 Query: 613 N-GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671 ++ L + G D ++ + LDRE + L VA D G PP + Sbjct: 399 EYSNVNVTLSGGEGHFGLTTRDNIIYLVIVSLPLDREIKPNYTLSVVATDTGNPPLHAAK 458 Query: 672 IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD 731 + + + DIND+ P FE + + E + GT++ ++ A D DEG N+ + YS+ D Sbjct: 459 TIFLTVTDINDNAPEFEKEIYHANVMEVADPGTSVIQVTAIDKDEGNNSAIAYSLLDTPD 518 Query: 732 SNS--FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--PPLWNDVRVEILVTDV 787 ++S F +++ G + T +D E+ +V+ + PP+ + V + + DV Sbjct: 519 THSQWFQIDSNSGL----ITTRAHIDCETDPVPQLIVVAKDNGFPPMSSTGTVLVTIHDV 574 Query: 788 NDNAPV 793 NDN P+ Sbjct: 575 NDNEPI 580 Score = 162 bits (394), Expect = 1e-37 Identities = 143/494 (28%), Positives = 212/494 (42%), Gaps = 33/494 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I VLD ND++P F E A D D+G+ Y I V+ + Sbjct: 132 IRVLDENDNAPTFPTALMNIEFPENTPRDVKRTLNPARDLDLGRYNTQRYNI--VSGNVN 189 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N D+ +I+G LDRE Y+++V+A D +P L Sbjct: 190 NAFRLSSHRERDGVLYLDL-QING---------FLDRETTPAYSLVVEALDGGNPP---L 236 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 T+++ I D NDN P F++ Y +V E+ ++ + ++ ATD D G N + YA Sbjct: 237 RGQMTVNITIQDVNDNQPIFNQSRYFATVPENATI--GTTVLQVYATDQDAGENGMVEYA 294 Query: 191 IIG--GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 I + F ID +G +S+ K LD+E + LV+ A+D G T + I + Sbjct: 295 INRRQSDKDQMFRIDPNTGLISVNKPLDFETKELHELVVVAKDRGLQPLETTAFVSIRVT 354 Query: 249 DVNDNAPRFYTSLFQES----VSENVPIGYSIVRVQAYDADEGVN-AELTYTMTDKDYTG 303 DVNDN P + +SE+ G + R+ D D + + T++ + G Sbjct: 355 DVNDNQPIINVIFLSDDATPKISESAQPGEFVARISVNDPDSKTEYSNVNVTLSGGE--G 412 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 + L T D V S LDRE + Y L V ATD G+PP A T Sbjct: 413 HFGLT-TRDNIIYLVIVSLPLDREIKPNYTLSVVATDTGNPPLHAAKTIFLTVTDINDNA 471 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGG-NTRGRFSITSQNGR 420 F Y + E PGT V+ +TA D DE N + Y + +T ++ N Sbjct: 472 PEFEKEIYHANVMEVADPGTSVIQVTAIDKDEGNNSAIAYSLLDTPDTHSQWFQIDSNS- 530 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASV 478 GLIT +D + + L V A D+G S T V + I D N+ P+F+ + Y SV Sbjct: 531 GLITTRAHIDCETDPVPQLIVVAKDNGFPPMSSTGTVLVTIHDVNDNEPIFDQSFYNVSV 590 Query: 479 FEDAPIGTTVLVVS 492 E+ P G +L VS Sbjct: 591 AENEPKGRCILKVS 604 Score = 118 bits (285), Expect = 2e-24 Identities = 89/290 (30%), Positives = 134/290 (46%), Gaps = 32/290 (11%) Query: 521 DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580 D I+ TG I T LLDRE + Y L +P + V I V+D NDN P Sbjct: 90 DTDLAIDHTTGEIRTKVLLDREKRASYSLVA------IPLSGENVRVVIRVLDENDNAPT 143 Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVG---------LNGRIH--YELDPKDREEGS 629 F L E+ + A D D+G ++G ++ + L +G Sbjct: 144 FPTALMNIEFPENTPRDVKRTLNPARDLDLGRYNTQRYNIVSGNVNNAFRLSSHRERDGV 203 Query: 630 FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES 689 +D ++ N LDRE+ + L A+DGG PP + V+I I+D+ND+ P+F Sbjct: 204 LYLD-----LQINGFLDRETTPAYSLVVEALDGGNPPLRGQMTVNITIQDVNDNQPIFNQ 258 Query: 690 DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI--KGGDDSNSFSLETRQGSDKAE 747 + EN+ IGTT+ ++ A D D G N +V Y+I + D F ++ G Sbjct: 259 SRYFATVPENATIGTTVLQVYATDQDAGENGMVEYAINRRQSDKDQMFRIDPNTGL---- 314 Query: 748 LVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVM 794 + LD+E+ ++ +ELV+ A PL V I VTDVNDN P++ Sbjct: 315 ISVNKPLDFET-KELHELVVVAKDRGLQPLETTAFVSIRVTDVNDNQPII 363 >UniRef50_Q4SJS0 Cluster: Chromosome 1 SCAF14573, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 1 SCAF14573, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 734 Score = 234 bits (572), Expect = 3e-59 Identities = 197/706 (27%), Positives = 318/706 (45%), Gaps = 43/706 (6%) Query: 100 LTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSV 159 L R +L E+ ++ T P D + I D NDN P F + + V Sbjct: 51 LDREALCPEETEAERCIILLTAVVGPSGDLIQFPVIIE----DVNDNEPYFEKSEIHLWV 106 Query: 160 DEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLV--KTLDY 217 ED +V + ++ ++A D D G NS + Y + N + +SLV LD Sbjct: 107 SEDATVGTS-LLLDVQAVDRDAGRNSEVHYRLEDPNGVFGLTFKEDGPIISLVVQTALDR 165 Query: 218 EQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE-SVSENVPIGYSI 276 E Y + + A D GS S T L++ + DV+DN P F + ++ + P + Sbjct: 166 ETRDFYEVKLEAADCGSNPLSATATLIVTVTDVDDNCPSFSPDNPRSVTIPGDSPRSMLV 225 Query: 277 VRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLV 336 +V+A D D NA + Y+++ K + ++D +G + + L +T + L V Sbjct: 226 AQVRAIDPDSATNAAIIYSLSPK-VSERAKKLFSLDSLTGDIRLAQDLHSDTSEELLLKV 284 Query: 337 TATDGGDPPRSATATXXXXXXXXXXXXXXF-MPGQYEVELAEDEPPGTPVVTLTATDADE 395 A+ PP T G+++ + A P P L + + Sbjct: 285 LASSQHCPPADTLVTVSILPKAYRELMIKIAFIGEHQ-KGAMVLPENQPPTALAILELEG 343 Query: 396 DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV-----SATDSGGRS 450 DN + FS++ QNG+ L++ ++PLD + + Y + V SA S Sbjct: 344 DNSFISSSLTIENKVPFSLSPQNGKYLLSTSKPLDHEMKSDYSIGVVARGTSADGSASAP 403 Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510 ++++ + D N+ AP F + Y V E+ G T+L VSA+D+D G N ++TY L + Sbjct: 404 SRHILRVMVADVNDNAPNFLRSHYQLEVEENNRPGMTLLHVSASDADGGCNGRVTYRLGN 463 Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570 H F ++P TG ++ + LDRE + +L+ V ARD G P L V + Sbjct: 464 --------HTSTVFSVHPVTGRLSASTSLDREQQAAHLIRVFARDSGSPPLESAATVSVR 515 Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630 V+D NDN PVF + + ED + T V V +D D G NG + EL K+ G F Sbjct: 516 VLDQNDNAPVFVTPHFIFFVPEDVPLFTEVGAVSVSDPDEGDNGNM--ELFFKN-NGGPF 572 Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPVF-- 687 ++ G++ T LD E ++L +A D G P +ST V I + D+ND+PP Sbjct: 573 CVNSTQGILHTTTNLDHEIEQRYELYLLASDRGYPSALTSTSRVTIFVVDVNDNPPKVIL 632 Query: 688 ---ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS---FSLETRQ 741 S CLT + ++ GT + +I A D D G N+ V Y++ + + S F +++R Sbjct: 633 PSSNSSCLT--VPADTIAGTVVTKIHAIDEDSGLNSEVTYTVVAPEPARSTAVFKVDSRS 690 Query: 742 GS-DKAELVTMVDLDYESPRKKYELVIRAASP-PLWNDVRVEILVT 785 G+ AE + DL + +V P PL+ V V +LV+ Sbjct: 691 GNITTAEQLLQKDL---GMHHLFVVVRDQGKPIPLYTTVWVNLLVS 733 Score = 205 bits (501), Expect = 1e-50 Identities = 198/689 (28%), Positives = 319/689 (46%), Gaps = 71/689 (10%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLT-LKATDQDIGKNAEVEYTIELVTADTLNPE 73 D ND+ P FE + V E A+ GT++L ++A D+D G+N+EV Y +E +P Sbjct: 89 DVNDNEPYFEKSEIHLWVSEDATVGTSLLLDVQAVDRDAGRNSEVHYRLE-------DPN 141 Query: 74 DAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSST 133 F+ DG +L+ + +LDRE Y V ++A D S+ LS+T Sbjct: 142 GVFGL----------TFKEDGPIISLVVQTALDRETRDFYEVKLEAADCG---SNPLSAT 188 Query: 134 ATIHVNIIDDNDNYPQFS-EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI- 191 AT+ V + D +DN P FS + +V++ D + ++A+++A D D N+AI Y++ Sbjct: 189 ATLIVTVTDVDDNCPSFSPDNPRSVTIPGD--SPRSMLVAQVRAIDPDSATNAAIIYSLS 246 Query: 192 --IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 + + FS+DSL+GD+ L + L + L + A P T + ++I Sbjct: 247 PKVSERAKKLFSLDSLTGDIRLAQDLHSDTSEELLLKVLASSQHCPPAD--TLVTVSI-- 302 Query: 250 VNDNAPRFYTSLFQE--SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 P+ Y L + + E+ + Q A + E + T + Sbjct: 303 ----LPKAYRELMIKIAFIGEHQKGAMVLPENQPPTALAILELEGDNSFISSSLTIENKV 358 Query: 308 PITIDPRSG--WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX----XXXXXXXXX 361 P ++ P++G + TS LD E ++ Y + V A G SA+A Sbjct: 359 PFSLSPQNGKYLLSTSKPLDHEMKSDYSIGVVAR-GTSADGSASAPSRHILRVMVADVND 417 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNG 419 F+ Y++E+ E+ PG ++ ++A+DAD + R+ Y + G +T FS+ G Sbjct: 418 NAPNFLRSHYQLEVEENNRPGMTLLHVSASDADGGCNGRVTYRL-GNHTSTVFSVHPVTG 476 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTAS 477 R ++ + LD +Q+ +++ V A DSG A V + + D N+ APVF + Sbjct: 477 R--LSASTSLDREQQAAHLIRVFARDSGSPPLESAATVSVRVLDQNDNAPVFVTPHFIFF 534 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 V ED P+ T V VS +D D G N + ++ F +N G + T Sbjct: 535 VPEDVPLFTEVGAVSVSDPDEGDNGNMELFFK---------NNGGPFCVNSTQGILHTTT 585 Query: 538 LLDRETMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTAN-----IM 591 LD E Y L + A D G PS L+ T+ V I VVDVNDN P K L ++N + Sbjct: 586 NLDHEIEQRYELYLLASDRGYPSALTSTSRVTIFVVDVNDNPP--KVILPSSNSSCLTVP 643 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKD--REEGSFVIDPASGVIRTNKALDRES 649 D + GT V+++ A D D GLN + Y + + R F +D SG I T + L ++ Sbjct: 644 ADTIAGTVVTKIHAIDEDSGLNSEVTYTVVAPEPARSTAVFKVDSRSGNITTAEQLLQKD 703 Query: 650 VATHDLKAVAIDGGTP-PQSSTVIVHIKI 677 + H L V D G P P +TV V++ + Sbjct: 704 LGMHHLFVVVRDQGKPIPLYTTVWVNLLV 732 Score = 197 bits (480), Expect = 4e-48 Identities = 173/591 (29%), Positives = 262/591 (44%), Gaps = 37/591 (6%) Query: 218 EQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277 E+ + R +I PS + Q + I DVNDN P F S VSE+ +G S++ Sbjct: 59 EETEAERCIILLTAVVGPS-GDLIQFPVIIEDVNDNEPYFEKSEIHLWVSEDATVGTSLL 117 Query: 278 R-VQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLV 336 VQA D D G N+E+ Y + D + G L D + LDRET+ Y++ + Sbjct: 118 LDVQAVDRDAGRNSEVHYRLEDPN--GVFGLTFKEDGPIISLVVQTALDRETRDFYEVKL 175 Query: 337 TATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ-YEVELAEDEPPGTPVVTLTATDADE 395 A D G P SATAT F P V + D P V + A D D Sbjct: 176 EAADCGSNPLSATATLIVTVTDVDDNCPSFSPDNPRSVTIPGDSPRSMLVAQVRAIDPDS 235 Query: 396 DNR--LHYEIT---GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS 450 + Y ++ + FS+ S G I +AQ L +L V A+ Sbjct: 236 ATNAAIIYSLSPKVSERAKKLFSLDSLTGD--IRLAQDLHSDTSEELLLKVLASSQHCPP 293 Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510 +V ++I + + + G VL + + + I ++ +S Sbjct: 294 ADTLVTVSILPK-----AYRELMIKIAFIGEHQKGAMVLPENQPPTALAI-LELEGD-NS 346 Query: 511 EISNEAVAHHDQQFVINPQTGA--ITTNKLLDRETMSGYLLTVTARD---GGVPSLSDTT 565 IS+ + F ++PQ G ++T+K LD E S Y + V AR G S Sbjct: 347 FISSSLTIENKVPFSLSPQNGKYLLSTSKPLDHEMKSDYSIGVVARGTSADGSASAPSRH 406 Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625 + + V DVNDN P F + Y + E+ G ++ V A+DAD G NGR+ Y L + Sbjct: 407 ILRVMVADVNDNAPNFLRSHYQLEVEENNRPGMTLLHVSASDADGGCNGRVTYRLG--NH 464 Query: 626 EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685 F + P +G + + +LDRE A H ++ A D G+PP S V +++ D ND+ P Sbjct: 465 TSTVFSVHPVTGRLSASTSLDREQQAAHLIRVFARDSGSPPLESAATVSVRVLDQNDNAP 524 Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745 VF + F++ E+ P+ T +G + DPDEG N + K ++ F + + QG Sbjct: 525 VFVTPHFIFFVPEDVPLFTEVGAVSVSDPDEGDNGNMELFFK--NNGGPFCVNSTQGI-- 580 Query: 746 AELVTMVDLDYESPRKKYELVIRAAS----PPLWNDVRVEILVTDVNDNAP 792 L T +LD+E ++YEL + A+ L + RV I V DVNDN P Sbjct: 581 --LHTTTNLDHEI-EQRYELYLLASDRGYPSALTSTSRVTIFVVDVNDNPP 628 Score = 130 bits (313), Expect = 7e-28 Identities = 99/339 (29%), Positives = 155/339 (45%), Gaps = 32/339 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ V D ND++P F Y+ V E G T+L + A+D D G N V Y + T+ Sbjct: 409 RVMVADVNDNAPNFLRSHYQLEVEENNRPGMTLLHVSASDADGGCNGRVTYRLGNHTST- 467 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 VF + +G L SLDRE+ A + + V A D SP Sbjct: 468 -------------------VFSVHPVTGRLSASTSLDREQQAAHLIRVFARDSGSP---P 505 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L S AT+ V ++D NDN P F + V ED+ + + + +D D G N + Sbjct: 506 LESAATVSVRVLDQNDNAPVFVTPHFIFFVPEDVPLFTE--VGAVSVSDPDEGDNGNME- 562 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR-SNTTQLLINIR 248 + N F ++S G + LD+E + Y L + A D G PS ++T+++ I + Sbjct: 563 -LFFKNNGGPFCVNSTQGILHTTTNLDHEIEQRYELYLLASDRGYPSALTSTSRVTIFVV 621 Query: 249 DVNDNAPRFYTSLFQES---VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 DVNDN P+ S V + G + ++ A D D G+N+E+TYT+ + + Sbjct: 622 DVNDNPPKVILPSSNSSCLTVPADTIAGTVVTKIHAIDEDSGLNSEVTYTVVAPEPARST 681 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP 344 + +D RSG + T+ QL ++ + L V D G P Sbjct: 682 AV-FKVDSRSGNITTAEQLLQKDLGMHHLFVVVRDQGKP 719 Score = 122 bits (293), Expect = 2e-25 Identities = 134/520 (25%), Positives = 217/520 (41%), Gaps = 27/520 (5%) Query: 366 FMPGQYEVELAEDEPPGTPV---VTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL 422 F + + ++ED GT + V DA ++ +HY + N G F +T + + Sbjct: 97 FEKSEIHLWVSEDATVGTSLLLDVQAVDRDAGRNSEVHYRLEDPN--GVFGLTFKEDGPI 154 Query: 423 ITVAQPLDFKQERR--YVLTVSATDSGGR--SDTAMVQINITDANNYAPVFE-NAPYTAS 477 I++ +E R Y + + A D G S TA + + +TD ++ P F + P + + Sbjct: 155 ISLVVQTALDRETRDFYEVKLEAADCGSNPLSATATLIVTVTDVDDNCPSFSPDNPRSVT 214 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 + D+P V V A D D NA I YSLS ++S A + F ++ TG I + Sbjct: 215 IPGDSPRSMLVAQVRAIDPDSATNAAIIYSLSPKVSERA----KKLFSLDSLTGDIRLAQ 270 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 L +T LL V A P +DT V +S++ E + K + + A+V Sbjct: 271 DLHSDTSEELLLKVLASSQHCPP-ADTL-VTVSILPKAYRELMIKIA-FIGEHQKGAMV- 326 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEG-SFVIDPASG--VIRTNKALDRESVATHD 654 +Q A + L G + E F + P +G ++ T+K LD E + + Sbjct: 327 LPENQPPTALAILELEGDNSFISSSLTIENKVPFSLSPQNGKYLLSTSKPLDHEMKSDYS 386 Query: 655 LKAVAID---GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711 + VA G+ S I+ + + D+ND+ P F + EN+ G T+ + A Sbjct: 387 IGVVARGTSADGSASAPSRHILRVMVADVNDNAPNFLRSHYQLEVEENNRPGMTLLHVSA 446 Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771 D D G N V Y + G S FS+ G A T +D + ++ + S Sbjct: 447 SDADGGCNGRVTYRL-GNHTSTVFSVHPVTGRLSAS--TSLDREQQAAHLIRVFARDSGS 503 Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRI 831 PPL + V + V D NDNAPV IF +D G V D D D + Sbjct: 504 PPLESAATVSVRVLDQNDNAPVFVTPHFIFFVPEDVPLFTEVGAVSVSDPDEGDNGNMEL 563 Query: 832 LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 NN +N T G + + L+ + + + + +D Sbjct: 564 FFKNNGGPFCVNSTQGILHTTTNLDHEIEQRYELYLLASD 603 Score = 72.1 bits (169), Expect = 2e-10 Identities = 64/237 (27%), Positives = 104/237 (43%), Gaps = 31/237 (13%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND++PVF + V E T V + +D D G N +E L + Sbjct: 514 VRVLDQNDNAPVFVTPHFIFFVPEDVPLFTEVGAVSVSDPDEGDNGNME----LFFKNNG 569 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P F ++ G L T +LD E RY + + A+D+ P L Sbjct: 570 GP-----------------FCVNSTQGILHTTTNLDHEIEQRYELYLLASDRGYP--SAL 610 Query: 131 SSTATIHVNIIDDNDNYPQF---SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 +ST+ + + ++D NDN P+ S + ++V D V+ KI A D D G NS + Sbjct: 611 TSTSRVTIFVVDVNDNPPKVILPSSNSSCLTVPAD--TIAGTVVTKIHAIDEDSGLNSEV 668 Query: 188 RYAIIG---GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 Y ++ + F +DS SG+++ + L + + + L + +D G P TT Sbjct: 669 TYTVVAPEPARSTAVFKVDSRSGNITTAEQLLQKDLGMHHLFVVVRDQGKPIPLYTT 725 >UniRef50_Q60H51 Cluster: Protocadherin2-gamma-v5-sCP1; n=11; Clupeocephala|Rep: Protocadherin2-gamma-v5-sCP1 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 969 Score = 233 bits (570), Expect = 5e-59 Identities = 157/570 (27%), Positives = 273/570 (47%), Gaps = 27/570 (4%) Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 ++ + ++D+NDNAP F +SEN +G +A D D G+N +Y + D Sbjct: 129 RVTVEVQDINDNAPLFPKESVNLEISENAVLGARFPLDRAMDTDVGLNGIQSYKLHPTDN 188 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 +T + + +LDRE + + +L++ ATDGG P +S T Sbjct: 189 FKLEVHSLTDGNKYIEMILQRELDREERDEIKLVLLATDGGSPQKSGTVKIHVTILDAND 248 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH----YEITGGNTRGRFSITSQ 417 ++ E+ E+ P GT + T++A DADE H + + R F+I S+ Sbjct: 249 NAPVCKQSVFKTEVRENSPAGTVMGTVSAADADEGVNGHVSYYFALANKEERELFNINSE 308 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTAS 477 G +T+ LD++ + Y L ++A D GG SDT + I++TD N+ P + ++ + Sbjct: 309 TGE--VTLLAHLDYESQNSYQLNINARDKGGLSDTCKIVIDVTDENDNPPTIQLMSFSNT 366 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 + E++P+GTTV V++ D+D G N + +S++ I + + + + ++ T+ Sbjct: 367 IAENSPVGTTVAVINVEDADSGKNGLVHFSINQNIPFKIESTFSEYY-------SLITDD 419 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 +LDRET++ Y +T+ D G P+ + + + DVNDN P F Y + E+ G Sbjct: 420 MLDRETVTEYNITILVSDQGSPARHSNKTLNVKISDVNDNPPKFGSDEYKTFVNENNSPG 479 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKD---REEGSFV-IDPASGVIRTNKALDRESVATH 653 ++ V A DAD G N ++ Y L +D S V +D +G + K+ D E + + Sbjct: 480 VTILTVKANDADWGPNAQLSYFLKDEDIRGAPLSSLVSVDALTGTVHAVKSFDFEQLKSF 539 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP--VFESDCLTFYISENSP----IGTTIG 707 A DGG+PP SS V + I I+D ND+ P ++ ++E P +G + Sbjct: 540 SFNVTARDGGSPPLSSEVTITINIQDQNDNAPQVLYPVQTGASVVAEIVPRAVDVGYLVT 599 Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 ++ A D D G NA + Y ++ D F + + G + V V D ++ ++K +V+ Sbjct: 600 KVVAVDVDSGQNAWLSYKLQKAPDRALFEVGLQNG--EIRTVRQV-TDKDAVKQKLTVVV 656 Query: 768 RAASPPLWNDVRVEILVTDVNDNAPVMKDF 797 P + V V I V + V+ +F Sbjct: 657 EDNGQPSRSAV-VSINVAVADSFPEVLSEF 685 Score = 215 bits (526), Expect = 1e-53 Identities = 174/600 (29%), Positives = 271/600 (45%), Gaps = 33/600 (5%) Query: 97 GALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT 156 G L+ + +DRE++ + T + + + + V + D NDN P F +++ Sbjct: 93 GTLVVKERIDREELCKQTT--PCSFSFDLIVENPIQLHRVTVEVQDINDNAPLFPKESVN 150 Query: 157 VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG-----DVSL 211 + + E+ + + + A D DVG N Y + + + SL+ ++ L Sbjct: 151 LEISENAVLGARFPLDR--AMDTDVGLNGIQSYKL-HPTDNFKLEVHSLTDGNKYIEMIL 207 Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271 + LD E+ +LV+ A DGGSP +S T ++ + I D NDNAP S+F+ V EN P Sbjct: 208 QRELDREERDEIKLVLLATDGGSPQKSGTVKIHVTILDANDNAPVCKQSVFKTEVRENSP 267 Query: 272 IGYSIVRVQAYDADEGVNAELTY--TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329 G + V A DADEGVN ++Y + +K+ +L I+ +G V LD E+Q Sbjct: 268 AGTVMGTVSAADADEGVNGHVSYYFALANKE---EREL-FNINSETGEVTLLAHLDYESQ 323 Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389 YQL + A D G S T + +AE+ P GT V + Sbjct: 324 NSYQLNINARDKGG--LSDTCKIVIDVTDENDNPPTIQLMSFSNTIAENSPVGTTVAVIN 381 Query: 390 ATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447 DAD ++ +H+ I N + T LIT LD + Y +T+ +D G Sbjct: 382 VEDADSGKNGLVHFSI-NQNIPFKIESTFSEYYSLIT-DDMLDRETVTEYNITILVSDQG 439 Query: 448 --GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505 R + + I+D N+ P F + Y V E+ G T+L V A D+D G NAQ++ Sbjct: 440 SPARHSNKTLNVKISDVNDNPPKFGSDEYKTFVNENNSPGVTILTVKANDADWGPNAQLS 499 Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTT 565 Y L E A ++ TG + K D E + + VTARDGG P LS Sbjct: 500 YFLKDEDIRGAPL--SSLVSVDALTGTVHAVKSFDFEQLKSFSFNVTARDGGSPPLSSEV 557 Query: 566 DVEISVVDVNDNEPVFKQQLYT-----ANIMEDAL-VGTSVSQVGATDADVGLNGRIHYE 619 + I++ D NDN P + T A I+ A+ VG V++V A D D G N + Y+ Sbjct: 558 TITINIQDQNDNAPQVLYPVQTGASVVAEIVPRAVDVGYLVTKVVAVDVDSGQNAWLSYK 617 Query: 620 LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679 L K + F + +G IRT + + + L V D G P +S+ V +++ + D Sbjct: 618 LQ-KAPDRALFEVGLQNGEIRTVRQVTDKDAVKQKLTVVVEDNGQPSRSAVVSINVAVAD 676 Score = 185 bits (450), Expect = 2e-44 Identities = 142/470 (30%), Positives = 221/470 (47%), Gaps = 41/470 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + +LD ND++PV + ++ VRE + +GT + T+ A D D G N V Y L Sbjct: 241 VTILDANDNAPVCKQSVFKTEVRENSPAGTVMGTVSAADADEGVNGHVSYYFALA----- 295 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N E+ +++F I+ +G + A LD E Y + + A D+ L Sbjct: 296 NKEE------------RELFNINSETGEVTLLAHLDYESQNSYQLNINARDKGG-----L 338 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S T I +++ D+NDN P +++ ++ E+ V +A I DAD G N + ++ Sbjct: 339 SDTCKIVIDVTDENDNPPTIQLMSFSNTIAENSPV--GTTVAVINVEDADSGKNGLVHFS 396 Query: 191 IIGGNTQMQFSIDSLSGDV-SLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 I N + F I+S + SL+ LD E V Y + I D GSP+R + L + I Sbjct: 397 I---NQNIPFKIESTFSEYYSLITDDMLDRETVTEYNITILVSDQGSPARHSNKTLNVKI 453 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NVD 306 DVNDN P+F + ++ V+EN G +I+ V+A DAD G NA+L+Y + D+D G + Sbjct: 454 SDVNDNPPKFGSDEYKTFVNENNSPGVTILTVKANDADWGPNAQLSYFLKDEDIRGAPLS 513 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 +++D +G V+ D E + VTA DGG PP S+ T Sbjct: 514 SLVSVDALTGTVHAVKSFDFEQLKSFSFNVTARDGGSPPLSSEVTITINIQDQNDNAPQV 573 Query: 367 M-PGQYEVELAEDEPP-----GTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQN 418 + P Q + + P G V + A D D L Y++ R F + QN Sbjct: 574 LYPVQTGASVVAEIVPRAVDVGYLVTKVVAVDVDSGQNAWLSYKLQKAPDRALFEVGLQN 633 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468 G + TV Q D K + LTV D+G S +A+V IN+ A+++ V Sbjct: 634 GE-IRTVRQVTD-KDAVKQKLTVVVEDNGQPSRSAVVSINVAVADSFPEV 681 >UniRef50_Q9Y5H6 Cluster: Protocadherin alpha 8 precursor; n=204; Mammalia|Rep: Protocadherin alpha 8 precursor - Homo sapiens (Human) Length = 950 Score = 231 bits (566), Expect = 2e-58 Identities = 172/614 (28%), Positives = 277/614 (45%), Gaps = 25/614 (4%) Query: 87 QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146 +D+ + ++G L + +DRE++ + + + + DR + V + D NDN Sbjct: 72 RDLLEVSLQNGILFVNSRIDREELCGRSA--ECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129 Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206 P F K + V E + D+ + A+DADVGANS + Y + + ++S + Sbjct: 130 PPVFRVKDQKLFVSES-RMPDSRFPLE-GASDADVGANSVLTYRL-SSHDYFMLDVNSKN 186 Query: 207 GDVSLV-----KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261 + LV K+LD E ++ L + A DGG P + T QLL+ + DVNDNAP F S Sbjct: 187 DENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSE 246 Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321 ++ + EN G +++++ A D DEG N ++Y+ T +D +ID +G + Sbjct: 247 YEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVID-HFSIDRNTGEIVIR 305 Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381 G LD E + Y++L+ ATD G PP + T + + ED Sbjct: 306 GNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQF 365 Query: 382 GTPVVTLTATDADEDNRLHYEIT-GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440 GT + ++ D D + + + T +N L+ + LD ++ Y L Sbjct: 366 GTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLV-LDSALDRERVSAYELV 424 Query: 441 VSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498 V+A D G S TA + + + D N+ AP F YT V E+ P G + VSA D+D Sbjct: 425 VTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADA 484 Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558 NA ++YSL E ++ ++G + + LD E + V+ARD GV Sbjct: 485 QENALVSYSLVERRVGERSL--SSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGV 542 Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQQLY-----TANIMEDALVGTS--VSQVGATDADVG 611 P L +++ V+D NDN P + A+ + VG V++V A DAD G Sbjct: 543 PPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSG 602 Query: 612 LNGRIHYELDP-KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST 670 N + YEL P F + +G I T + LD H L + D G P ++T Sbjct: 603 YNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTAT 662 Query: 671 VIVHIKIEDINDSP 684 V + + + +P Sbjct: 663 ATVLVSLVESGQAP 676 Score = 211 bits (515), Expect = 2e-52 Identities = 163/549 (29%), Positives = 242/549 (44%), Gaps = 32/549 (5%) Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + ++DVNDN P F + VSE+ A DAD G N+ LTY ++ DY Sbjct: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYF-M 179 Query: 305 VDLPITIDPRS-GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 +D+ D + LDRE + L +TATDGG P + T Sbjct: 180 LDVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNA 239 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITG---GNTRGRFSITSQN 418 F +YEV + E+ GT V+ L A+D DE + + Y FSI Sbjct: 240 PTFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNT 299 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTA 476 G I + LDF+QE Y + + ATD G + V + I D N+ P + Sbjct: 300 GE--IVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSL 357 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 V EDA GT + ++S D D G N Q+T SL + + V+ + ++ + Sbjct: 358 PVREDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYY-------SLVLD 410 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 LDRE +S Y L VTARDGG PSL T + + V DVNDN P F Q YT + E+ Sbjct: 411 SALDRERVSAYELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPP 470 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPK---DREEGSFV-IDPASGVIRTNKALDRESVAT 652 G + V A DAD N + Y L + +R S++ + SG + + LD E + Sbjct: 471 GCHIFTVSARDADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELEL 530 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF-------ESDCLTFYISENSPIGTT 705 + A D G PP S V + + + D ND+ P + + + G Sbjct: 531 LQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHV 590 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD-YESPRKKYE 764 + ++RA D D G NA + Y ++ ++S + R G E+ T LD +SPR + Sbjct: 591 VAKVRAVDADSGYNAWLSYELQPA--ASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLL 648 Query: 765 LVIRAASPP 773 ++++ P Sbjct: 649 VLVKDHGEP 657 Score = 184 bits (449), Expect = 2e-44 Identities = 118/378 (31%), Positives = 192/378 (50%), Gaps = 12/378 (3%) Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFE 480 + + + LD + + L ++ATD G T VQ+ +T D N+ AP FE + Y +FE Sbjct: 194 LVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFE 253 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 +A GTTV+ ++A+D D G N I+YS +S + + H F I+ TG I LD Sbjct: 254 NADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDH----FSIDRNTGEIVIRGNLD 309 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 E + Y + + A D G P ++ V + ++D NDN P + + EDA GT + Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 + + D D G NG++ L P + ++ + ALDRE V+ ++L A Sbjct: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLV-LDSALDRERVSAYELVVTAR 428 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 DGG+P +T + +++ D+ND+ P F T ++ EN+P G I + A D D NA Sbjct: 429 DGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488 Query: 721 VVHYSI---KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS-PPLWN 776 +V YS+ + G+ S S + S K + +D + E ++++ R A PPL + Sbjct: 489 LVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHE-ELELLQFQVSARDAGVPPLGS 547 Query: 777 DVRVEILVTDVNDNAPVM 794 +V +++ V D NDNAP + Sbjct: 548 NVTLQVFVLDENDNAPAL 565 Score = 177 bits (430), Expect = 5e-42 Identities = 140/463 (30%), Positives = 208/463 (44%), Gaps = 37/463 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND++P FE +YE + E A +GTTV+ L A+D D G N + Y+ + +T+ Sbjct: 230 VTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLV-ETM 288 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 V D F ID +G ++ R +LD E+ Y +L+ ATD+ P + Sbjct: 289 ---------------VIDHFSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHP---PM 330 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + T+ V I+D NDN P+ + + ++ V ED VIA I D D GAN + + Sbjct: 331 AGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQF--GTVIALISVNDLDSGANGQVTCS 388 Query: 191 IIGGNTQMQFS-IDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 ++ + F + + SLV LD E+V +Y LV+ A+DGGSPS T L + + Sbjct: 389 LM---PHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARDGGSPSLWATASLSVEV 445 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY-TGNVD 306 DVNDNAP F + V EN P G I V A DAD NA ++Y++ ++ ++ Sbjct: 446 ADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERSLS 505 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 I++ SG VY LD E Q V+A D G PP + T Sbjct: 506 SYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPAL 565 Query: 367 MP-------GQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQ 417 + G + G V + A DAD L YE+ + R Sbjct: 566 LEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPAASSPRIPFRVG 625 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT 460 G I+ + LD R+ L V D G + TA + ++ Sbjct: 626 LYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668 Score = 151 bits (366), Expect = 3e-34 Identities = 132/450 (29%), Positives = 202/450 (44%), Gaps = 25/450 (5%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE--I 512 V + + D N+ PVF V E + + A+D+DVG N+ +TY LSS Sbjct: 119 VDVEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYF 178 Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572 + + +D+ ++ + K LDRE + L +TA DGG P L+ T + ++V+ Sbjct: 179 MLDVNSKNDENKLVE-----LVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVL 233 Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP--KDREEGSF 630 DVNDN P F+Q Y I E+A GT+V ++ A+D D G NG I Y + + F Sbjct: 234 DVNDNAPTFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHF 293 Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690 ID +G I LD E + + A D G PP + V ++I D ND+ P Sbjct: 294 SIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALT 353 Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750 L+ + E++ GT I I +D D G N V S+ F L + LV Sbjct: 354 SLSLPVREDAQFGTVIALISVNDLDSGANGQVTCSLM---PHVPFKL-VSTFKNYYSLVL 409 Query: 751 MVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC 807 LD E YELV+ A SP LW + + V DVNDNAP + ++ Sbjct: 410 DSALDRERV-SAYELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENN 468 Query: 808 FPVGPFGRVPAYDADVTDK-------LQYRILSGNNANLILLNETTGSMTLSPQLNTNVP 860 P V A DAD + ++ R+ + ++ I ++ +G + L+ Sbjct: 469 PPGCHIFTVSARDADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEEL 528 Query: 861 KLATMEVSVTD-GVNEIKAMMQLSVRLITE 889 +L +VS D GV + + + L V ++ E Sbjct: 529 ELLQFQVSARDAGVPPLGSNVTLQVFVLDE 558 Score = 122 bits (294), Expect = 1e-25 Identities = 97/326 (29%), Positives = 148/326 (45%), Gaps = 21/326 (6%) Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 SV E+A GT V ++ D+G+ L + A H ++ Q G + N Sbjct: 34 SVPEEAKHGTFVGRIA---QDLGLELA---ELVPRLFRVASKRHRDLLEVSLQNGILFVN 87 Query: 537 KLLDRETMSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 +DRE + G + + V V++ V DVNDN PVF+ + + E + Sbjct: 88 SRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDNPPVFRVKDQKLFVSESRM 147 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKD---REEGSFVIDPASGVIRTNKALDRESVAT 652 + GA+DADVG N + Y L D + S + + K+LDRE Sbjct: 148 PDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDENKLVELVLRKSLDREDAPA 207 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 H L A DGG P + TV + + + D+ND+ P FE I EN+ GTT+ ++ A Sbjct: 208 HHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIKLNAS 267 Query: 713 DPDEGPNAVVHYSIKGGDDS---NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 DPDEG N + YS ++ + FS++ G E+V +LD+E Y+++I A Sbjct: 268 DPDEGANGAISYSFNSLVETMVIDHFSIDRNTG----EIVIRGNLDFEQ-ENLYKILIDA 322 Query: 770 AS---PPLWNDVRVEILVTDVNDNAP 792 PP+ V + + D NDN P Sbjct: 323 TDKGHPPMAGHCTVLVRILDKNDNVP 348 >UniRef50_UPI0000E80F11 Cluster: PREDICTED: similar to protocadherin LKC; n=2; Gallus gallus|Rep: PREDICTED: similar to protocadherin LKC - Gallus gallus Length = 1497 Score = 231 bits (565), Expect = 2e-58 Identities = 234/819 (28%), Positives = 375/819 (45%), Gaps = 91/819 (11%) Query: 36 ASSGTTVLTLKATDQDIGKNAEV-EYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDG 94 A+SG T T + ++ ++ E+ +L+ D D F + Sbjct: 218 AASGNTAPIFNMTIVYVAEDLQIGEFAFQLMAYDI----DGDTITYSISGSDSFYFTANA 273 Query: 95 RSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKT 154 ++G + R LDRE AR T+LV +D +++ +S I V D NDN P F Sbjct: 274 QTGVVTLRNLLDRESQARLTILVTVSDG---INEAVSRRLPIIVE--DRNDNAPVFQNLP 328 Query: 155 YTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI---IGGNTQMQ--FSIDSLSGDV 209 Y SV E+ +V VI + A D+D G + + Y+I I T+ F I S SG V Sbjct: 329 YETSVLENTTV--GSVIYTVFANDSDTGTAARVSYSIQEVIPDTTKNHRLFYILS-SGSV 385 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSR------SNTTQLLINIRDVNDNAPRFYTSLFQ 263 L +LDY ++L I AQDGG R S+TT L I + DV + PRF + Sbjct: 386 VLNNSLDYTMNTFFQLKILAQDGGGLLRNETVIQSSTTYLSITVIDVPNLDPRFLNEPYS 445 Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323 SV E P+G +++ V A D D GVN +++Y+ T N +P I+ +G + S Sbjct: 446 GSVPEGCPVGTTVLTVTAMDRDTGVNDKISYSFT------NASVPFAINDTTGTITVSQV 499 Query: 324 LDRETQAKYQLL--VTATDG-----GDPPRSATATXXXXXXXXXXXXXXFM--------- 367 LDRE ++L V A + G+ +++T + Sbjct: 500 LDREQLPSEEVLLEVLARESNLDIYGNVAQASTLVTVLVTDVNDNKPQFYQCSSNCNFIH 559 Query: 368 -PGQYEVELAEDEPPGTPV--VTLTATDADEDNRLHYEI-TGGNTRGRFSITSQ----NG 419 + + E PV +++ A D D+ +E+ G + F+++ G Sbjct: 560 TQSNFTGSIIEHSSSKVPVSNLSIVARDPDKGTNGTFELYLQGTSASAFTVSPTRIVGTG 619 Query: 420 RGLITVAQP--LDFKQERRYVLTVSATDSGGRSD---TAMVQINITDANNYAPVFENAPY 474 I V P +D++ V+ + A D+G +D TA V I++ D N++ P F + Y Sbjct: 620 EVQILVQNPSAVDYEITHVMVVQLIANDTGNPTDCCSTATVTIDLIDTNDHIPEFPQSTY 679 Query: 475 TASVFEDAPIGTTVLV-VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA- 532 V E++P GT + ++A D D G + QITY L E E F++N +GA Sbjct: 680 NLRVMENSPDGTIIATNITAYDPDSGASGQITYQLLPESIQEI-------FMVNATSGAV 732 Query: 533 -ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 + LLDRE Y + A+DGG ++ TT +EI+V+D NDNEP+ Y ++ Sbjct: 733 LVRNGSLLDREMRPVYYANLQAKDGG--NMMGTTLLEITVLDKNDNEPIIIGS-YFISVE 789 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV- 650 E V T + + D + N + +++ P +F I +G + + LDRE+V Sbjct: 790 EGQNVSTQIRAID-NDEEGTPNSELGFKIVP-GLYSNNFTISQTTGELHNIEPLDREAVD 847 Query: 651 --ATHDLKAVAI-DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 A + V + D G P S+ V V I + D+ND+ PVF F I E+S G+ +G Sbjct: 848 DEAGQMVVTVEVYDHGVPQLSTMVNVTITVADVNDNTPVFLQQSYEFSIFESSD-GSFVG 906 Query: 708 EIRAHDPDEGP-NAVVHYSIKGGDDSNSFSL-ETRQG----SDKAELVTMVDLDYESPRK 761 ++ A D D N+ + + ++ S++F + +R G S + L V ++YE+ ++ Sbjct: 907 DVMATDADRTEINSRISFQLEKSTGSSNFLISSSRLGPGNYSGRLSLNPGVSVNYEAMQE 966 Query: 762 K-YELVIRA---ASPPLWNDVRVEILVT--DVNDNAPVM 794 K + LV+ A A+ N V +LV DVND P + Sbjct: 967 KLFSLVVLAENTAADNSGNIANVSVLVNILDVNDEPPTI 1005 Score = 197 bits (481), Expect = 3e-48 Identities = 228/874 (26%), Positives = 370/874 (42%), Gaps = 95/874 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND++PVF+ YE SV E + G+ + T+ A D D G A V Y+I+ V DT Sbjct: 312 IIVEDRNDNAPVFQNLPYETSVLENTTVGSVIYTVFANDSDTGTAARVSYSIQEVIPDTT 371 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +F I SG+++ SLD + + + A D + + Sbjct: 372 KNHR--------------LFYILS-SGSVVLNNSLDYTMNTFFQLKILAQDGGGLLRNET 416 Query: 131 ---SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 SST + + +ID + P+F + Y+ SV E V + + A D D G N I Sbjct: 417 VIQSSTTYLSITVIDVPNLDPRFLNEPYSGSVPEGCPV--GTTVLTVTAMDRDTGVNDKI 474 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIR--AQDGGSPSRSNTTQ--- 242 Y+ N + F+I+ +G +++ + LD EQ+ S +++ A++ N Q Sbjct: 475 SYSFT--NASVPFAINDTTGTITVSQVLDREQLPSEEVLLEVLARESNLDIYGNVAQAST 532 Query: 243 -LLINIRDVNDNAPRFY---------------TSLFQESVSENVPIGYSIVRVQAYDADE 286 + + + DVNDN P+FY T E S VP+ S + + A D D+ Sbjct: 533 LVTVLVTDVNDNKPQFYQCSSNCNFIHTQSNFTGSIIEHSSSKVPV--SNLSIVARDPDK 590 Query: 287 GVNA--ELTYTMTDKD-YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD 343 G N EL T +T + + V +D E + + A D G+ Sbjct: 591 GTNGTFELYLQGTSASAFTVSPTRIVGTGEVQILVQNPSAVDYEITHVMVVQLIANDTGN 650 Query: 344 PPR-SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT-LTATDADE--DNRL 399 P +TAT F Y + + E+ P GT + T +TA D D ++ Sbjct: 651 PTDCCSTATVTIDLIDTNDHIPEFPQSTYNLRVMENSPDGTIIATNITAYDPDSGASGQI 710 Query: 400 HYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINI 459 Y++ + + F + + +G L+ LD + Y + A D G T +++I + Sbjct: 711 TYQLLPESIQEIFMVNATSGAVLVRNGSLLDREMRPVYYANLQAKDGGNMMGTTLLEITV 770 Query: 460 TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAH 519 D N+ P+ + Y SV E + T + + D + N+++ + + + Sbjct: 771 LDKNDNEPIIIGS-YFISVEEGQNVSTQIRAID-NDEEGTPNSELGFKIVPGL------- 821 Query: 520 HDQQFVINPQTGAITTNKLLDRETMSG----YLLTVTARDGGVPSLSDTTDVEISVVDVN 575 + F I+ TG + + LDRE + ++TV D GVP LS +V I+V DVN Sbjct: 822 YSNNFTISQTTGELHNIEPLDREAVDDEAGQMVVTVEVYDHGVPQLSTMVNVTITVADVN 881 Query: 576 DNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVIDP 634 DN PVF QQ Y +I E + G+ V V ATDAD +N RI ++L+ K +F+I Sbjct: 882 DNTPVFLQQSYEFSIFESS-DGSFVGDVMATDADRTEINSRISFQLE-KSTGSSNFLISS 939 Query: 635 A-------SGVIRTNK--ALDRESVATHDLKAVAIDGGTPPQSS----TVIVHIKIEDIN 681 + SG + N +++ E++ V + T +S V V + I D+N Sbjct: 940 SRLGPGNYSGRLSLNPGVSVNYEAMQEKLFSLVVLAENTAADNSGNIANVSVLVNILDVN 999 Query: 682 DSPP-VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV-HYSI---KGGDDSNSFS 736 D PP + S + EN + + A D D + V S+ KGG + Sbjct: 1000 DEPPTIVPSSLEGVSVRENGTQQDLVHTVFASDRDTNHSLVFEELSVACYKGGSSAGEVC 1059 Query: 737 LE-TRQGSDKAELVTMVDLDYE------SPRKKYELVIRAASPPLWNDVRVEILVTDVND 789 + + + L D+DYE + +L + + N+ ++I + D+ND Sbjct: 1060 WDWFVLLPNGSVLANSFDIDYELCDVVQLTMRVEDLYTQKGNQYSQNET-LQIRIIDIND 1118 Query: 790 NAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD 822 NAPV F + PV V A DAD Sbjct: 1119 NAPVFLPVSGTFVVVPEISPVDLQVATVKATDAD 1152 Score = 177 bits (430), Expect = 5e-42 Identities = 191/671 (28%), Positives = 295/671 (43%), Gaps = 81/671 (12%) Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325 V+E++ IG ++ AYD D +TY+++ D T + ++G V LD Sbjct: 234 VAEDLQIGEFAFQLMAYDIDGDT---ITYSISGSD-----SFYFTANAQTGVVTLRNLLD 285 Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 RE+QA+ +LVT +DG + S +P YE + E+ G+ + Sbjct: 286 RESQARLTILVTVSDGINEAVSRRLPIIVEDRNDNAPVFQNLP--YETSVLENTTVGSVI 343 Query: 386 VTLTATDADEDN--RLHY---EITGGNTRGR--FSITSQNGRGLITVAQPLDFKQERRYV 438 T+ A D+D R+ Y E+ T+ F I S G + + LD+ + Sbjct: 344 YTVFANDSDTGTAARVSYSIQEVIPDTTKNHRLFYILSS---GSVVLNNSLDYTMNTFFQ 400 Query: 439 LTVSATDSGG--------RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 L + A D GG +S T + I + D N P F N PY+ SV E P+GTTVL Sbjct: 401 LKILAQDGGGLLRNETVIQSSTTYLSITVIDVPNLDPRFLNEPYSGSVPEGCPVGTTVLT 460 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG--YL 548 V+A D D G+N +I+YS +N +V F IN TG IT +++LDRE + L Sbjct: 461 VTAMDRDTGVNDKISYS----FTNASV-----PFAINDTTGTITVSQVLDREQLPSEEVL 511 Query: 549 LTVTARDGGVPSLSD----TTDVEISVVDVNDNEPVF-----------KQQLYTANIMED 593 L V AR+ + + +T V + V DVNDN+P F Q +T +I+E Sbjct: 512 LEVLARESNLDIYGNVAQASTLVTVLVTDVNDNKPQFYQCSSNCNFIHTQSNFTGSIIEH 571 Query: 594 ALVGTSVSQVG--ATDADVGLNGRIHYELDPKDREEGSFVIDP----ASG----VIRTNK 643 + VS + A D D G NG +EL + +F + P +G +++ Sbjct: 572 SSSKVPVSNLSIVARDPDKGTNGT--FELYLQGTSASAFTVSPTRIVGTGEVQILVQNPS 629 Query: 644 ALDRESVATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 A+D E ++ +A D G P ST V I + D ND P F + ENSP Sbjct: 630 AVDYEITHVMVVQLIANDTGNPTDCCSTATVTIDLIDTNDHIPEFPQSTYNLRVMENSPD 689 Query: 703 GTTIG-EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761 GT I I A+DPD G + + Y + F + G A LV L R Sbjct: 690 GTIIATNITAYDPDSGASGQITYQLLPESIQEIFMVNATSG---AVLVRNGSLLDREMRP 746 Query: 762 KYELVIRAA-SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD 820 Y ++A + +EI V D NDN P++ F + ++ V R D Sbjct: 747 VYYANLQAKDGGNMMGTTLLEITVLDKNDNEPII--IGSYFISVEEGQNVSTQIRAIDND 804 Query: 821 ADVT--DKLQYRILSGNNANLILLNETTGSM-TLSPQLNTNVPKLA---TMEVSVTD-GV 873 + T +L ++I+ G +N +++TTG + + P V A + V V D GV Sbjct: 805 EEGTPNSELGFKIVPGLYSNNFTISQTTGELHNIEPLDREAVDDEAGQMVVTVEVYDHGV 864 Query: 874 NEIKAMMQLSV 884 ++ M+ +++ Sbjct: 865 PQLSTMVNVTI 875 Score = 158 bits (384), Expect = 2e-36 Identities = 138/515 (26%), Positives = 244/515 (47%), Gaps = 52/515 (10%) Query: 373 VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432 V +AED G L A D D D + Y I+G ++ F T+ G++T+ LD + Sbjct: 232 VYVAEDLQIGEFAFQLMAYDIDGDT-ITYSISGSDS---FYFTANAQTGVVTLRNLLDRE 287 Query: 433 QERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492 + R + V+ +D + + + I + D N+ APVF+N PY SV E+ +G+ + V Sbjct: 288 SQARLTILVTVSDGINEAVSRRLPIIVEDRNDNAPVFQNLPYETSVLENTTVGSVIYTVF 347 Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552 A DSD G A+++YS+ E+ + +H ++++ +G++ N LD + + L + Sbjct: 348 ANDSDTGTAARVSYSI-QEVIPDTTKNHRLFYILS--SGSVVLNNSLDYTMNTFFQLKIL 404 Query: 553 ARDGG------VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 A+DGG S TT + I+V+DV + +P F + Y+ ++ E VGT+V V A Sbjct: 405 AQDGGGLLRNETVIQSSTTYLSITVIDVPNLDPRFLNEPYSGSVPEGCPVGTTVLTVTAM 464 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD--LKAVAIDG-- 662 D D G+N +I Y F I+ +G I ++ LDRE + + + L+ +A + Sbjct: 465 DRDTGVNDKISYSF---TNASVPFAINDTTGTITVSQVLDREQLPSEEVLLEVLARESNL 521 Query: 663 ---GTPPQSSTVIVHIKIEDINDSPPVF---ESDCLTFYISEN----------SPIGTTI 706 G Q+ST +V + + D+ND+ P F S+C + N S + + Sbjct: 522 DIYGNVAQAST-LVTVLVTDVNDNKPQFYQCSSNCNFIHTQSNFTGSIIEHSSSKVPVSN 580 Query: 707 GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD----LDYESPR-K 761 I A DPD+G N ++ G +++F++ + E+ +V +DYE Sbjct: 581 LSIVARDPDKGTNGTFELYLQ-GTSASAFTVSPTRIVGTGEVQILVQNPSAVDYEITHVM 639 Query: 762 KYELVIRAASPP--LWNDVRVEILVTDVNDNAPVMKDFQIIFN-NYKDCFPVGPF--GRV 816 +L+ P + V I + D ND+ P Q +N + P G + Sbjct: 640 VVQLIANDTGNPTDCCSTATVTIDLIDTNDHIPEFP--QSTYNLRVMENSPDGTIIATNI 697 Query: 817 PAYDAD--VTDKLQYRILSGNNANLILLNETTGSM 849 AYD D + ++ Y++L + + ++N T+G++ Sbjct: 698 TAYDPDSGASGQITYQLLPESIQEIFMVNATSGAV 732 Score = 157 bits (381), Expect = 4e-36 Identities = 194/770 (25%), Positives = 318/770 (41%), Gaps = 87/770 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V+D + P F + Y SV EG GTTVLT+ A D+D G N ++ Y+ + Sbjct: 427 ITVIDVPNLDPRFLNEPYSGSVPEGCPVGTTVLTVTAMDRDTGVNDKISYSFTNASVP-- 484 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS--PVSD 128 F I+ +G + LDRE++ VL++ + S + Sbjct: 485 -------------------FAINDTTGTITVSQVLDREQLPSEEVLLEVLARESNLDIYG 525 Query: 129 RLSSTAT-IHVNIIDDNDNYPQF-----------SEKTYTVSVDEDISVTDNPVIAKIKA 176 ++ +T + V + D NDN PQF ++ +T S+ E S I A Sbjct: 526 NVAQASTLVTVLVTDVNDNKPQFYQCSSNCNFIHTQSNFTGSIIEHSSSKVPVSNLSIVA 585 Query: 177 TDADVGANSAIRYAIIGGNTQMQFSIDSL----SGDVSLV----KTLDYEQVRSYRLVIR 228 D D G N + G + F++ +G+V ++ +DYE + + Sbjct: 586 RDPDKGTNGTFEL-YLQGTSASAFTVSPTRIVGTGEVQILVQNPSAVDYEITHVMVVQLI 644 Query: 229 AQDGGSPSRS-NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV-RVQAYDADE 286 A D G+P+ +T + I++ D ND+ P F S + V EN P G I + AYD D Sbjct: 645 ANDTGNPTDCCSTATVTIDLIDTNDHIPEFPQSTYNLRVMENSPDGTIIATNITAYDPDS 704 Query: 287 GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT--SGQLDRETQAKYQLLVTATDGGDP 344 G + ++TY + + ++ ++ SG V LDRE + Y + A DGG+ Sbjct: 705 GASGQITYQLLPE----SIQEIFMVNATSGAVLVRNGSLLDREMRPVYYANLQAKDGGN- 759 Query: 345 PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN-RLHYEI 403 T + G Y + + E + T + + + N L ++I Sbjct: 760 --MMGTTLLEITVLDKNDNEPIIIGSYFISVEEGQNVSTQIRAIDNDEEGTPNSELGFKI 817 Query: 404 TGGNTRGRFSITSQNGRGLITVAQPLDFK----QERRYVLTVSATDSGGRSDTAMVQINI 459 G F+I+ G + +PLD + + + V+TV D G + MV + I Sbjct: 818 VPGLYSNNFTISQTTGE--LHNIEPLDREAVDDEAGQMVVTVEVYDHGVPQLSTMVNVTI 875 Query: 460 T--DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNEA 516 T D N+ PVF Y S+FE + G+ V V ATD+D IN++I++ L + Sbjct: 876 TVADVNDNTPVFLQQSYEFSIFESSD-GSFVGDVMATDADRTEINSRISFQLEKSTGSSN 934 Query: 517 VAHHDQQFVINPQTGAITTNK--LLDRETMSGYL--LTVTARDGGVPSLSDTTDVEI--S 570 + +G ++ N ++ E M L L V A + + + +V + + Sbjct: 935 FLISSSRLGPGNYSGRLSLNPGVSVNYEAMQEKLFSLVVLAENTAADNSGNIANVSVLVN 994 Query: 571 VVDVNDNEP-VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629 ++DVND P + L ++ E+ V V A+D D + + EL + GS Sbjct: 995 ILDVNDEPPTIVPSSLEGVSVRENGTQQDLVHTVFASDRDTN-HSLVFEELSVACYKGGS 1053 Query: 630 ---------FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP---QSSTVIVHIKI 677 FV+ P V+ + +D E L D T S + I+I Sbjct: 1054 SAGEVCWDWFVLLPNGSVLANSFDIDYELCDVVQLTMRVEDLYTQKGNQYSQNETLQIRI 1113 Query: 678 EDINDSPPVFESDCLTFYI-SENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 DIND+ PVF TF + E SP+ + ++A D D G V ++I Sbjct: 1114 IDINDNAPVFLPVSGTFVVVPEISPVDLQVATVKATDADSGLEGTVFFNI 1163 Score = 122 bits (293), Expect = 2e-25 Identities = 165/648 (25%), Positives = 278/648 (42%), Gaps = 85/648 (13%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-LKATDQDIGKNAEVEYTIELVTADT 69 I+++D NDH P F Y V E + GT + T + A D D G + ++ Y Sbjct: 662 IDLIDTNDHIPEFPQSTYNLRVMENSPDGTIIATNITAYDPDSGASGQITYQ-------- 713 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR--ASLDREKVARYTVLVKATDQASPVS 127 L PE +Q++F ++ SGA+L R + LDRE Y ++A D + Sbjct: 714 LLPES-----------IQEIFMVNATSGAVLVRNGSLLDREMRPVYYANLQAKDGGN--- 759 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA--NS 185 + T + + ++D NDN P +Y +SV+E +V+ +I+A D D NS Sbjct: 760 --MMGTTLLEITVLDKNDNEPIIIG-SYFISVEEGQNVS-----TQIRAIDNDEEGTPNS 811 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQ--DGGSPSRSNTT 241 + + I+ G F+I +G++ ++ LD E V + ++V+ + D G P S Sbjct: 812 ELGFKIVPGLYSNNFTISQTTGELHNIEPLDREAVDDEAGQMVVTVEVYDHGVPQLSTMV 871 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG-VNAELTYTMTDKD 300 + I + DVNDN P F ++ S+ E+ G + V A DAD +N+ +++ + Sbjct: 872 NVTITVADVNDNTPVFLQQSYEFSIFESSD-GSFVGDVMATDADRTEINSRISFQLEKS- 929 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLD---------RETQAK-YQLLVTA--TDGGDPPRSA 348 TG+ + I+ R G SG+L Q K + L+V A T + A Sbjct: 930 -TGSSNFLIS-SSRLGPGNYSGRLSLNPGVSVNYEAMQEKLFSLVVLAENTAADNSGNIA 987 Query: 349 TATXXXXXXXXXXXXXXFMPGQYE-VELAEDEPPGTPVVTLTATDADEDNRLHYE----- 402 + +P E V + E+ V T+ A+D D ++ L +E Sbjct: 988 NVSVLVNILDVNDEPPTIVPSSLEGVSVRENGTQQDLVHTVFASDRDTNHSLVFEELSVA 1047 Query: 403 -ITGGNTRGR----FSITSQNGRGLITVAQPLDFKQERRYVLTVSATD----SGGR-SDT 452 GG++ G + + NG ++ + +D++ LT+ D G + S Sbjct: 1048 CYKGGSSAGEVCWDWFVLLPNG-SVLANSFDIDYELCDVVQLTMRVEDLYTQKGNQYSQN 1106 Query: 453 AMVQINITDANNYAPVFENAPYTASVF-EDAPIGTTVLVVSATDSDVGINAQITYSLSSE 511 +QI I D N+ APVF T V E +P+ V V ATD+D G+ + +++ S Sbjct: 1107 ETLQIRIIDINDNAPVFLPVSGTFVVVPEISPVDLQVATVKATDADSGLEGTVFFNIISV 1166 Query: 512 I--SNEAVAH-HDQQFVI------NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 + + V + F + + G+I LD Y +TV ARD P + Sbjct: 1167 VLVQEDGVKRPFENLFKVVTSADQDSYIGSIQVASNLDSSLKGQYQVTVEARDSAAPQQA 1226 Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610 T + I VD + + Q + T + ++ L ++ AT A V Sbjct: 1227 TQTTLIIFTVD--QSYRIHLQFVTTVDEVQSNLESIRLALTSATKAGV 1272 Score = 67.3 bits (157), Expect = 6e-09 Identities = 94/374 (25%), Positives = 162/374 (43%), Gaps = 43/374 (11%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGK-NAEVEYTIELV 65 ++ I V D ND++PVF Q YE S+ E +S G+ V + ATD D + N+ + + +E Sbjct: 871 VNVTITVADVNDNTPVFLQQSYEFSIFE-SSDGSFVGDVMATDADRTEINSRISFQLEKS 929 Query: 66 TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125 T + + R+ G + ++ +EK+ ++++V A + A+ Sbjct: 930 TGSSNFLISSSRLGPGNYSG-----RLSLNPGVSVNYEAM-QEKL--FSLVVLAENTAAD 981 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYT-VSVDEDISVTDNPVIAKIKATDADVGAN 184 S +++ + + VNI+D ND P + VSV E + T ++ + A+D D + Sbjct: 982 NSGNIANVSVL-VNILDVNDEPPTIVPSSLEGVSVRE--NGTQQDLVHTVFASDRDTNHS 1038 Query: 185 SAIRYAII----GGNTQMQFSIDSL----SGDVSLVK-TLDYEQVRSYRLVIRAQD---- 231 + GG++ + D +G V +DYE +L +R +D Sbjct: 1039 LVFEELSVACYKGGSSAGEVCWDWFVLLPNGSVLANSFDIDYELCDVVQLTMRVEDLYTQ 1098 Query: 232 -GGSPSRSNTTQLLINIRDVNDNAPRFY-TSLFQESVSENVPIGYSIVRVQAYDADEGVN 289 G S++ T Q I I D+NDNAP F S V E P+ + V+A DAD G+ Sbjct: 1099 KGNQYSQNETLQ--IRIIDINDNAPVFLPVSGTFVVVPEISPVDLQVATVKATDADSGLE 1156 Query: 290 AELTYTMTD---------KDYTGNVDLPITI---DPRSGWVYTSGQLDRETQAKYQLLVT 337 + + + K N+ +T D G + + LD + +YQ+ V Sbjct: 1157 GTVFFNIISVVLVQEDGVKRPFENLFKVVTSADQDSYIGSIQVASNLDSSLKGQYQVTVE 1216 Query: 338 ATDGGDPPRSATAT 351 A D P ++ T Sbjct: 1217 ARDSAAPQQATQTT 1230 Score = 44.4 bits (100), Expect = 0.046 Identities = 47/173 (27%), Positives = 74/173 (42%), Gaps = 11/173 (6%) Query: 10 QINVLDCNDHSPVF-EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68 QI ++D ND++PVF + V E + V T+KATD D G V + I V Sbjct: 1110 QIRIIDINDNAPVFLPVSGTFVVVPEISPVDLQVATVKATDADSGLEGTVFFNIISVV-- 1167 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 L ED V D G++ ++LD +Y V V+A D A+P Sbjct: 1168 -LVQEDGVKRPFENLFKVVTSADQDSYIGSIQVASNLDSSLKGQYQVTVEARDSAAP--- 1223 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181 + ++ T+ + +D + + +VDE S ++ +A AT A V Sbjct: 1224 QQATQTTLIIFTVDQSYRI----HLQFVTTVDEVQSNLESIRLALTSATKAGV 1272 >UniRef50_UPI0000E80EB1 Cluster: PREDICTED: similar to cadherin-related neuronal receptor 3; n=1; Gallus gallus|Rep: PREDICTED: similar to cadherin-related neuronal receptor 3 - Gallus gallus Length = 695 Score = 230 bits (563), Expect = 4e-58 Identities = 191/627 (30%), Positives = 294/627 (46%), Gaps = 55/627 (8%) Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDG-GSPS 236 + G A R ++ + + SG + + LD E++ +S +R + P Sbjct: 53 EAGEAEARRLRLVARGRRASVEVSGASGALVVSSRLDREELCGKSAPCALRLEVLLDRPL 112 Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 R + + + D+NDNAPRF + SV EN P+ A DAD G NA+L+Y++ Sbjct: 113 R--VFHVEVEVTDINDNAPRFPNAYKNISVWENSPLNSRFPLEGASDADIGSNAQLSYSL 170 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 + ++ + S ++ + LDRE+ ++++L++TA+DGG P + T Sbjct: 171 SPSEHFALDVQRGEENLESLFLVLTKPLDRESLSEHRLVLTASDGGRPALTGTVQLVISV 230 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGG---NTRGR 411 F Y+V+L ED GT V + ATD DE + Y I + R Sbjct: 231 LDANDNAPQFNQSVYKVQLPEDAAEGTLVGRVAATDPDEGINQEFSYSIVSSVPASQRDS 290 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN 471 FSI + G I + LD++ R L + A D+G + P+ + Sbjct: 291 FSIDPRTGE--IRLRGLLDYEVVRLCELQIEARDNG-----------------FPPLSRH 331 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 V + A+D+D+G NAQ++YSLS +E A + N ++ Sbjct: 332 CKVVVQVLD-----------GASDADIGSNAQLSYSLSP---SEHFALDVKSPDDNLKSL 377 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 + LDRE++S + L +TA DGG P+L+ T + ISV+D NDN P F Q +Y + Sbjct: 378 FLVLTHPLDRESLSEHRLVLTASDGGRPALTGTVQLVISVLDANDNAPQFNQSVYKVQLP 437 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRES 649 EDA GT V +V ATD D G+N Y + + SF IDP +G IR LD E Sbjct: 438 EDAAEGTLVGRVAATDPDEGINQAFSYSIVSSVPASQRDSFSIDPRTGEIRLTGPLDFED 497 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 V H+L+ A D GTPP S V +++ D+ND+ P L+ + E++ +GT + + Sbjct: 498 VHQHELQIEARDKGTPPLSGHCSVILEVLDVNDNAPEVWVTSLSVPVPEDAALGTVVALL 557 Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSL-ETRQGSDKAELVTMVDLDYESPRKKYELVIR 768 D D GPN V +++ + F L T GS LV LD E +YE+ + Sbjct: 558 SVSDRDSGPNGRVRCAVR---PPSPFGLVATFAGS--YSLVLREALDRERV-SEYEVEVG 611 Query: 769 A---ASPPLWNDVRVEILVTDVNDNAP 792 A +PPL + + V+DVNDNAP Sbjct: 612 AEDGGAPPLRASRGLRVPVSDVNDNAP 638 Score = 217 bits (530), Expect = 4e-54 Identities = 176/632 (27%), Positives = 284/632 (44%), Gaps = 69/632 (10%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 H ++ V D ND++P F SV E + + A+D DIG NA++ Y++ Sbjct: 116 HVEVEVTDINDNAPRFPNAYKNISVWENSPLNSRFPLEGASDADIGSNAQLSYSLS---- 171 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 E ++ +F + LT+ LDRE ++ + +++ A+D P Sbjct: 172 ---PSEHFALDVQRGEENLESLFLV-------LTK-PLDRESLSEHRLVLTASDGGRPA- 219 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 L+ T + ++++D NDN PQF++ Y V + ED + ++ ++ ATD D G N Sbjct: 220 --LTGTVQLVISVLDANDNAPQFNQSVYKVQLPED--AAEGTLVGRVAATDPDEGINQEF 275 Query: 188 RYAIIGGNTQMQ---FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 Y+I+ Q FSID +G++ L LDYE VR L I A+D G P S +++ Sbjct: 276 SYSIVSSVPASQRDSFSIDPRTGEIRLRGLLDYEVVRLCELQIEARDNGFPPLSRHCKVV 335 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + + D +A + N + YS+ + + D K N Sbjct: 336 VQVLDGASDA----------DIGSNAQLSYSLSPSEHFALDV------------KSPDDN 373 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 + +S ++ + LDRE+ ++++L++TA+DGG P + T Sbjct: 374 L--------KSLFLVLTHPLDRESLSEHRLVLTASDGGRPALTGTVQLVISVLDANDNAP 425 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITG---GNTRGRFSITSQNG 419 F Y+V+L ED GT V + ATD DE + Y I + R FSI + G Sbjct: 426 QFNQSVYKVQLPEDAAEGTLVGRVAATDPDEGINQAFSYSIVSSVPASQRDSFSIDPRTG 485 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477 I + PLDF+ ++ L + A D G S V + + D N+ AP + Sbjct: 486 E--IRLTGPLDFEDVHQHELQIEARDKGTPPLSGHCSVILEVLDVNDNAPEVWVTSLSVP 543 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 V EDA +GT V ++S +D D G N ++ ++ VA + ++ + Sbjct: 544 VPEDAALGTVVALLSVSDRDSGPNGRVRCAVRPPSPFGLVATFAGSY-------SLVLRE 596 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LDRE +S Y + V A DGG P L + + + V DVNDN P F Q +YT E+ G Sbjct: 597 ALDRERVSEYEVEVGAEDGGAPPLRASRGLRVPVSDVNDNAPAFAQAVYTVLARENNAAG 656 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGS 629 ++++ A D D NGR+ Y + GS Sbjct: 657 AELARLWARDPDEAGNGRVSYSVAEGGAGSGS 688 Score = 175 bits (425), Expect = 2e-41 Identities = 110/315 (34%), Positives = 161/315 (51%), Gaps = 8/315 (2%) Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ--INITDANNYAPVFENAPYTASVFE 480 + + PLD + + L ++A+D G + T VQ I++ DAN+ AP F + Y + E Sbjct: 379 LVLTHPLDRESLSEHRLVLTASDGGRPALTGTVQLVISVLDANDNAPQFNQSVYKVQLPE 438 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 DA GT V V+ATD D GIN +YS+ S + A F I+P+TG I LD Sbjct: 439 DAAEGTLVGRVAATDPDEGINQAFSYSIVSSVP----ASQRDSFSIDPRTGEIRLTGPLD 494 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 E + + L + ARD G P LS V + V+DVNDN P + + EDA +GT V Sbjct: 495 FEDVHQHELQIEARDKGTPPLSGHCSVILEVLDVNDNAPEVWVTSLSVPVPEDAALGTVV 554 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 + + +D D G NGR+ + P G S + +ALDRE V+ ++++ A Sbjct: 555 ALLSVSDRDSGPNGRVRCAVRPPS-PFGLVATFAGSYSLVLREALDRERVSEYEVEVGAE 613 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 DGG PP ++ + + + D+ND+ P F T EN+ G + + A DPDE N Sbjct: 614 DGGAPPLRASRGLRVPVSDVNDNAPAFAQAVYTVLARENNAAGAELARLWARDPDEAGNG 673 Query: 721 VVHYSI-KGGDDSNS 734 V YS+ +GG S S Sbjct: 674 RVSYSVAEGGAGSGS 688 Score = 134 bits (324), Expect = 3e-29 Identities = 86/263 (32%), Positives = 136/263 (51%), Gaps = 15/263 (5%) Query: 92 IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151 + G SGAL+ + LDRE++ + + + DR + V + D NDN P+F Sbjct: 75 VSGASGALVVSSRLDREELCGKSA--PCALRLEVLLDRPLRVFHVEVEVTDINDNAPRFP 132 Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSL 211 +SV E+ + N A+DAD+G+N+ + Y++ + F++D G+ +L Sbjct: 133 NAYKNISVWENSPL--NSRFPLEGASDADIGSNAQLSYSL---SPSEHFALDVQRGEENL 187 Query: 212 -------VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 K LD E + +RLV+ A DGG P+ + T QL+I++ D NDNAP+F S+++ Sbjct: 188 ESLFLVLTKPLDRESLSEHRLVLTASDGGRPALTGTVQLVISVLDANDNAPQFNQSVYKV 247 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 + E+ G + RV A D DEG+N E +Y++ D +IDPR+G + G L Sbjct: 248 QLPEDAAEGTLVGRVAATDPDEGINQEFSYSIVSSVPASQRD-SFSIDPRTGEIRLRGLL 306 Query: 325 DRETQAKYQLLVTATDGGDPPRS 347 D E +L + A D G PP S Sbjct: 307 DYEVVRLCELQIEARDNGFPPLS 329 Score = 118 bits (283), Expect = 3e-24 Identities = 103/341 (30%), Positives = 155/341 (45%), Gaps = 31/341 (9%) Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV-INPQTGAITT 535 SV E+A GT VV D+G+ A + + VA + V ++ +GA+ Sbjct: 32 SVPEEAEAGT---VVGRLAQDLGLEAGEAEARRLRL----VARGRRASVEVSGASGALVV 84 Query: 536 NKLLDRETMSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 + LDRE + G R + + VE+ V D+NDN P F ++ E++ Sbjct: 85 SSRLDREELCGKSAPCALRLEVLLDRPLRVFHVEVEVTDINDNAPRFPNAYKNISVWENS 144 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG-------VIRTNKALDR 647 + + GA+DAD+G N ++ Y L P + F +D G + K LDR Sbjct: 145 PLNSRFPLEGASDADIGSNAQLSYSLSPSEH----FALDVQRGEENLESLFLVLTKPLDR 200 Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 ES++ H L A DGG P + TV + I + D ND+ P F + E++ GT +G Sbjct: 201 ESLSEHRLVLTASDGGRPALTGTVQLVISVLDANDNAPQFNQSVYKVQLPEDAAEGTLVG 260 Query: 708 EIRAHDPDEGPNAVVHYSIKG---GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764 + A DPDEG N YSI +SFS++ R G E+ LDYE R E Sbjct: 261 RVAATDPDEGINQEFSYSIVSSVPASQRDSFSIDPRTG----EIRLRGLLDYEVVR-LCE 315 Query: 765 LVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFN 802 L I A PPL +V + V D +A + + Q+ ++ Sbjct: 316 LQIEARDNGFPPLSRHCKVVVQVLDGASDADIGSNAQLSYS 356 >UniRef50_Q60H55 Cluster: Protocadherin2-gamma-v12-sCP1; n=8; Danio rerio|Rep: Protocadherin2-gamma-v12-sCP1 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 955 Score = 230 bits (562), Expect = 5e-58 Identities = 173/606 (28%), Positives = 284/606 (46%), Gaps = 26/606 (4%) Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 + ++ +G LL + +DRE + T Q + D TI V I D NDN Sbjct: 69 EYIELNRNTGLLLIKEKMDRESLCAKTTPCALHLQM--ILDNPMELYTITVEITDINDNA 126 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNT---QMQFSID- 203 P F ++ + + E V ++ K A D DVG NS Y++ + ++Q D Sbjct: 127 PNFQKRDFKFEISESAMVGARFMLGK--AFDPDVGTNSLQSYSLKPTDKFRLELQSQADG 184 Query: 204 SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263 S + ++ L K LD E S+ L++ A DGG P S T Q+ I + D+NDNAP F ++ Sbjct: 185 SKNVEMILQKALDREMQSSFTLLLEAFDGGDPVLSGTVQIHIAVLDINDNAPVFMQKEYK 244 Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323 + +E P G + V A D DEG N+E+TY ++D + D+ ++ ++G + +G Sbjct: 245 ATATEEAPKGSILTVVSATDTDEGSNSEVTYYISDTMDSVMADM-FLVNEQTGELILNGH 303 Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383 D E + Y+L + A D G + + + V +E GT Sbjct: 304 FDYEKVSHYELTIHAKDQGGLSNACKVIIDVLDVNDNSPSINILSSSHSV--SEGSKFGT 361 Query: 384 PVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL-ITVAQPLDFKQERRYVLTVS 442 + L D D + + F I SQ+ + Q LD ++E Y ++V Sbjct: 362 VIAMLNVDDLDSGASGQVQCV-MSEEIPFVIKSQSSNFFSLQTEQELDRERETEYNISVI 420 Query: 443 ATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 +D G S + + + I+D N+ PVF+ + Y A V E+ G ++ V A+D+D Sbjct: 421 CSDEGVPSLSSSVSLTVQISDVNDNPPVFKKSNYEAFVMENNTPGLSIFTVKASDADWNQ 480 Query: 501 NAQITYSL-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 NA+++Y L S +S +V+ + ++P +G IT + D ET+ + V A+DGG P Sbjct: 481 NARVSYILEDSTVSGVSVSSY---VSVHPDSGLITAVRSFDYETLKDFHFRVKAQDGGSP 537 Query: 560 SLSDTTDVEISVVDVNDNEP--VFKQQLYTANIME----DALVGTSVSQVGATDADVGLN 613 LS V+++V D NDN P ++ Q T+ + E A VG V++V A D D G N Sbjct: 538 PLSSNVTVKVTVQDQNDNAPQVLYPVQTGTSVVAEIVPRAADVGYLVTKVVAVDVDSGQN 597 Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673 + Y+L K + F + +G IRT + + + L V D G P +S+ V + Sbjct: 598 AWLSYKLQ-KAPDRALFEVGLQNGEIRTVRQVTDKDAVKQKLTVVVEDNGQPSRSAVVSI 656 Query: 674 HIKIED 679 ++ + D Sbjct: 657 NVAVAD 662 Score = 229 bits (561), Expect = 6e-58 Identities = 168/574 (29%), Positives = 277/574 (48%), Gaps = 36/574 (6%) Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT 302 + + I D+NDNAP F F+ +SE+ +G + +A+D D G N+ +Y++ D Sbjct: 115 ITVEITDINDNAPNFQKRDFKFEISESAMVGARFMLGKAFDPDVGTNSLQSYSLKPTDKF 174 Query: 303 GNVDLPITID-PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 ++L D ++ + LDRE Q+ + LL+ A DGGDP S T Sbjct: 175 -RLELQSQADGSKNVEMILQKALDREMQSSFTLLLEAFDGGDPVLSGTVQIHIAVLDIND 233 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITG---GNTRGRFSITS 416 FM +Y+ E+ P G+ + ++ATD DE ++ + Y I+ F + Sbjct: 234 NAPVFMQKEYKATATEEAPKGSILTVVSATDTDEGSNSEVTYYISDTMDSVMADMFLVNE 293 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTA 476 Q G ++ D+++ Y LT+ A D GG S+ V I++ D N+ +P + Sbjct: 294 QTGELILN--GHFDYEKVSHYELTIHAKDQGGLSNACKVIIDVLDVNDNSPSINILSSSH 351 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG---AI 533 SV E + GT + +++ D D G + Q+ +S EI FVI Q+ ++ Sbjct: 352 SVSEGSKFGTVIAMLNVDDLDSGASGQVQCVMSEEIP----------FVIKSQSSNFFSL 401 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593 T + LDRE + Y ++V D GVPSLS + + + + DVNDN PVFK+ Y A +ME+ Sbjct: 402 QTEQELDRERETEYNISVICSDEGVPSLSSSVSLTVQISDVNDNPPVFKKSNYEAFVMEN 461 Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDP---KDREEGSFV-IDPASGVIRTNKALDRES 649 G S+ V A+DAD N R+ Y L+ S+V + P SG+I ++ D E+ Sbjct: 462 NTPGLSIFTVKASDADWNQNARVSYILEDSTVSGVSVSSYVSVHPDSGLITAVRSFDYET 521 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP--VFESDCLTFYISENSP----IG 703 + + A DGG+PP SS V V + ++D ND+ P ++ T ++E P +G Sbjct: 522 LKDFHFRVKAQDGGSPPLSSNVTVKVTVQDQNDNAPQVLYPVQTGTSVVAEIVPRAADVG 581 Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY 763 + ++ A D D G NA + Y ++ D F + + G + V V D ++ ++K Sbjct: 582 YLVTKVVAVDVDSGQNAWLSYKLQKAPDRALFEVGLQNG--EIRTVRQV-TDKDAVKQKL 638 Query: 764 ELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDF 797 +V+ P + V V I V + V+ +F Sbjct: 639 TVVVEDNGQPSRSAV-VSINVAVADSFPEVLSEF 671 Score = 200 bits (487), Expect = 6e-49 Identities = 162/585 (27%), Positives = 265/585 (45%), Gaps = 61/585 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND++P F+ + ++ + E A G + KA D D+G N+ Y +L Sbjct: 117 VEITDINDNAPNFQKRDFKFEISESAMVGARFMLGKAFDPDVGTNSLQSY--------SL 168 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 P D + DG ++ ++ + +LDRE + +T+L++A D PV Sbjct: 169 KPTDKFRLELQS--------QADGSKNVEMILQKALDREMQSSFTLLLEAFDGGDPV--- 217 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LS T IH+ ++D NDN P F +K Y + E+ ++ + ATD D G+NS + Y Sbjct: 218 LSGTVQIHIAVLDINDNAPVFMQKEYKATATEE--APKGSILTVVSATDTDEGSNSEVTY 275 Query: 190 AIIGGNTQM---QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 I + F ++ +G++ L DYE+V Y L I A+D G SN +++I+ Sbjct: 276 YISDTMDSVMADMFLVNEQTGELILNGHFDYEKVSHYELTIHAKDQG--GLSNACKVIID 333 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + DVNDN+P SVSE G I + D D G + ++ M++ + Sbjct: 334 VLDVNDNSPSINILSSSHSVSEGSKFGTVIAMLNVDDLDSGASGQVQCVMSE-------E 386 Query: 307 LPITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 +P I +S + T +LDRE + +Y + V +D G P S++ + Sbjct: 387 IPFVIKSQSSNFFSLQTEQELDRERETEYNISVICSDEGVPSLSSSVSLTVQISDVNDNP 446 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITS----Q 417 F YE + E+ PG + T+ A+DAD ++ R+ Y + G S++S Sbjct: 447 PVFKKSNYEAFVMENNTPGLSIFTVKASDADWNQNARVSYILEDSTVSG-VSVSSYVSVH 505 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAP--VFENAP 473 GLIT + D++ + + V A D G S V++ + D N+ AP ++ Sbjct: 506 PDSGLITAVRSFDYETLKDFHFRVKAQDGGSPPLSSNVTVKVTVQDQNDNAPQVLYPVQT 565 Query: 474 YTASVFEDAP----IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 T+ V E P +G V V A D D G NA ++Y L A F + Q Sbjct: 566 GTSVVAEIVPRAADVGYLVTKVVAVDVDSGQNAWLSYKLQK-------APDRALFEVGLQ 618 Query: 530 TGAI-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 G I T ++ D++ + LTV D G PS S + ++V D Sbjct: 619 NGEIRTVRQVTDKDAVK-QKLTVVVEDNGQPSRSAVVSINVAVAD 662 Score = 184 bits (448), Expect = 3e-44 Identities = 143/470 (30%), Positives = 222/470 (47%), Gaps = 40/470 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I VLD ND++PVF ++Y+A+ E A G+ + + ATD D G N+EV Y I +DT+ Sbjct: 226 IAVLDINDNAPVFMQKEYKATATEEAPKGSILTVVSATDTDEGSNSEVTYYI----SDTM 281 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + + D+F ++ ++G L+ D EKV+ Y + + A DQ L Sbjct: 282 D------------SVMADMFLVNEQTGELILNGHFDYEKVSHYELTIHAKDQGG-----L 324 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+ + ++++D NDN P + + + SV E VIA + D D GA+ ++ Sbjct: 325 SNACKVIIDVLDVNDNSPSINILSSSHSVSEGSKF--GTVIAMLNVDDLDSGASGQVQCV 382 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 + + ++ F I S S + ++T LD E+ Y + + D G PS S++ L + I Sbjct: 383 M---SEEIPFVIKSQSSNFFSLQTEQELDRERETEYNISVICSDEGVPSLSSSVSLTVQI 439 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NVD 306 DVNDN P F S ++ V EN G SI V+A DAD NA ++Y + D +G +V Sbjct: 440 SDVNDNPPVFKKSNYEAFVMENNTPGLSIFTVKASDADWNQNARVSYILEDSTVSGVSVS 499 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 +++ P SG + D ET + V A DGG PP S+ T Sbjct: 500 SYVSVHPDSGLITAVRSFDYETLKDFHFRVKAQDGGSPPLSSNVTVKVTVQDQNDNAPQV 559 Query: 367 M-PGQYEVELAEDEPP-----GTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQN 418 + P Q + + P G V + A D D L Y++ R F + QN Sbjct: 560 LYPVQTGTSVVAEIVPRAADVGYLVTKVVAVDVDSGQNAWLSYKLQKAPDRALFEVGLQN 619 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468 G + TV Q D K + LTV D+G S +A+V IN+ A+++ V Sbjct: 620 GE-IRTVRQVTD-KDAVKQKLTVVVEDNGQPSRSAVVSINVAVADSFPEV 667 >UniRef50_UPI0000DB7673 Cluster: PREDICTED: similar to Cad74A CG6445-PA, isoform A; n=2; Apocrita|Rep: PREDICTED: similar to Cad74A CG6445-PA, isoform A - Apis mellifera Length = 1843 Score = 229 bits (560), Expect = 8e-58 Identities = 251/899 (27%), Positives = 393/899 (43%), Gaps = 93/899 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD--IGKNAEVEYTIELVTAD 68 I + D ND+ P FE ++Y +VREGA+S + ++ATD D + N +V Y+I + Sbjct: 583 IELEDVNDNKPAFEQKEYTRTVREGATSFDPQMFVRATDADGPMQGNGKVTYSISSHNSM 642 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR--YTVLVKATDQASPV 126 T DVF+I+ +G + ++ + R Y + ++ATD +P Sbjct: 643 T-----------------NDVFKINRDTGEVTMAKAVRSDDTERGIYELAIRATDAGTPP 685 Query: 127 ---SDRLSSTATIHVN---IIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD 180 RLS + N I N TY + E+ S + ++ A D D Sbjct: 686 LFSETRLSVRVGVPGNQKPIFRGNYKSNLPGPSTYRARLLENAS--PGTEVIRVVANDPD 743 Query: 181 VGANSAIRYAIIGGNTQMQFSIDSLSG--DVSLVKTLDYEQV-RSYRLVIRAQDGGSPSR 237 G +S ++Y I G + F IDS SG VS LD E Y +++ A D G+P R Sbjct: 744 -GRDSLLQYHIASG-AKDNFVIDSSSGVITVSPDARLDLESGGEKYEVIVYAIDSGTPVR 801 Query: 238 SN-TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 TT + +N+ DVN+ P F S + VSE IG +++V A D D +A L Y++ Sbjct: 802 ETATTTVTVNMIDVNNKPPTFNESTYLVYVSERAAIGEPVLKVAATDPDS--DAYLEYSI 859 Query: 297 TDK----DYTG---------NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG- 342 + D TG + I+ +G + + LD + A L V D Sbjct: 860 VEPIRAVDKTGVALKNTAPYDYKTAFRINSTTGLITVNRVLDYQVAAVVILTVQVQDLNA 919 Query: 343 --DPPRSATATXXXXXXXXXXXXXXFM--PG------QYEVELAEDEPPGTPVVTLTATD 392 D R T PG + + E++P GT ++ L+A + Sbjct: 920 VVDKERQITRVEVTIYIQAYSDDNPTFTNPGWSPNNPTIRISVPEEQPLGTTLLMLSARE 979 Query: 393 ADEDNRLH-YEITG-GNTRGRFSITSQNGRGLITVAQPLDFKQ-ERRYV---LTVSATDS 446 + +E+ + G ++ Q+G + +++ LD++ ++++ + A D Sbjct: 980 PTTGYPVQRFELVREDDDEGYVNVGVQSGN--VVLSKRLDYEALNQKFIQFKVRALARDY 1037 Query: 447 G--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504 + A V + + D N+ PVF Y SV E VL V ATD D Q Sbjct: 1038 EITRKMSEANVIVEVQDTNDNNPVFAQKDYKISVLESEKPSKIVLNVKATDMDSSNTEQE 1097 Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTG--AITTNKLLDRETMSGYLLTVTARD---GGVP 559 E+ + + F + P TG I TN LDRE S V A D GG Sbjct: 1098 VRRGYGEVRYSLIGENANMFEVEPITGNIQIATNTTLDREKQSVLRFYVVASDMPQGGAE 1157 Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619 S V + V+DVNDN P F+Q+ YTA I E+A G SV + ATD D G I+YE Sbjct: 1158 QRSTRALVTVDVLDVNDNAPTFEQEAYTAVIPENAPSGVSVVNITATDPDEDKGGVINYE 1217 Query: 620 LDPKDREEGSFVIDPASGVIRTNKAL-DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678 + + G F ID +G I + +AL + + ++ DGG P S VI+ + I Sbjct: 1218 IIDEGEASGLFEIDHKTGEIYSARALTGKGRTEPYIMRIRGEDGGEPELYSDVILTLYIG 1277 Query: 679 DI--NDSPPVFESDCL--TFYISENSPIGTTIGEIRAHDPDEG--PNAVVHYSIKGGDDS 732 D+ ND P+F L YISENS IG+ + ++ A DPD+ PN + + + Sbjct: 1278 DVVSNDGVPLFIRPTLEEVAYISENSTIGSPVFQVVASDPDDPNLPNGKITFKFLEDGNF 1337 Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVND 789 + R S+ + T LD E+ + Y L++ A +PP ++++V D++D Sbjct: 1338 GKDASAFRINSETGLITTRKLLDREA-KDSYTLILVAQDLGNPPQQATRVLQVIVNDIDD 1396 Query: 790 NAPVMK---DFQIIFNNYKDCFPVG-PFGRVPAYDADVTDK--LQYRILSGNNANLILL 842 + P K D + + P+G G + A D D+ + + Y I+ GN A L L+ Sbjct: 1397 HKPHFKRNLDSPPVELAVLEETPIGAKVGVIEAIDEDIGENGMIDYAIVYGNEAGLFLV 1455 Score = 221 bits (541), Expect = 2e-55 Identities = 239/846 (28%), Positives = 397/846 (46%), Gaps = 118/846 (13%) Query: 28 YEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQ 87 Y A + E AS GT V+ + A D D G+++ ++Y I + Sbjct: 720 YRARLLENASPGTEVIRVVANDPD-GRDSLLQYHI--------------------ASGAK 758 Query: 88 DVFRIDGRSGALLTR--ASLDREKVA-RYTVLVKATDQASPVSDRLSSTATIHVNIIDDN 144 D F ID SG + A LD E +Y V+V A D +PV R ++T T+ VN+ID N Sbjct: 759 DNFVIDSSSGVITVSPDARLDLESGGEKYEVIVYAIDSGTPV--RETATTTVTVNMIDVN 816 Query: 145 DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG---------- 194 + P F+E TY V V E ++ + PV+ K+ ATD D +++ + Y+I+ Sbjct: 817 NKPPTFNESTYLVYVSERAAIGE-PVL-KVAATDPD--SDAYLEYSIVEPIRAVDKTGVA 872 Query: 195 --NT-----QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS---PSRSNT-TQL 243 NT + F I+S +G +++ + LDY+ L ++ QD + R T ++ Sbjct: 873 LKNTAPYDYKTAFRINSTTGLITVNRVLDYQVAAVVILTVQVQDLNAVVDKERQITRVEV 932 Query: 244 LINIRDVNDNAPRFYTS-------LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 I I+ +D+ P F + SV E P+G +++ + A + G + + Sbjct: 933 TIYIQAYSDDNPTFTNPGWSPNNPTIRISVPEEQPLGTTLLMLSAREPTTGYPVQRFELV 992 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ----AKYQLLVTATDGGDPPRSATATX 352 + D G V++ + +SG V S +LD E ++++ A D + + A Sbjct: 993 REDDDEGYVNVGV----QSGNVVLSKRLDYEALNQKFIQFKVRALARDYEITRKMSEANV 1048 Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRF 412 F Y++ + E E P V+ + ATD D N E+ G R+ Sbjct: 1049 IVEVQDTNDNNPVFAQKDYKISVLESEKPSKIVLNVKATDMDSSNT-EQEVRRGYGEVRY 1107 Query: 413 SITSQNGR--------GLITVAQPLDFKQERRYVLT--VSATD--SGG---RSDTAMVQI 457 S+ +N G I +A +E++ VL V A+D GG RS A+V + Sbjct: 1108 SLIGENANMFEVEPITGNIQIATNTTLDREKQSVLRFYVVASDMPQGGAEQRSTRALVTV 1167 Query: 458 NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517 ++ D N+ AP FE YTA + E+AP G +V+ ++ATD D I Y EI +E Sbjct: 1168 DVLDVNDNAPTFEQEAYTAVIPENAPSGVSVVNITATDPDEDKGGVINY----EIIDEGE 1223 Query: 518 AHHDQQFVINPQTGAI-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV-- 574 A F I+ +TG I + L + Y++ + DGG P L + + + DV Sbjct: 1224 A--SGLFEIDHKTGEIYSARALTGKGRTEPYIMRIRGEDGGEPELYSDVILTLYIGDVVS 1281 Query: 575 NDNEPVFKQQLY--TANIMEDALVGTSVSQVGATDAD-VGL-NGRIHYE-LDPKD--REE 627 ND P+F + A I E++ +G+ V QV A+D D L NG+I ++ L+ + ++ Sbjct: 1282 NDGVPLFIRPTLEEVAYISENSTIGSPVFQVVASDPDDPNLPNGKITFKFLEDGNFGKDA 1341 Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687 +F I+ +G+I T K LDRE+ ++ L VA D G PPQ +T ++ + + DI+D P F Sbjct: 1342 SAFRINSETGLITTRKLLDREAKDSYTLILVAQDLGNPPQQATRVLQVIVNDIDDHKPHF 1401 Query: 688 ----ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLET---- 739 +S + + E +PIG +G I A D D G N ++ Y+I G+++ F +E Sbjct: 1402 KRNLDSPPVELAVLEETPIGAKVGVIEAIDEDIGENGMIDYAIVYGNEAGLFLVERLENN 1461 Query: 740 --------RQGSDKAE--LVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVND 789 R ++A+ L+T+ Y + KK ++V + + ++ +V + V D++D Sbjct: 1462 SAVIRSNGRLDRERADHHLLTIKCFPYST--KKGDIVPKPYNRQDPSERQVLVKVLDIDD 1519 Query: 790 NAPVMK 795 N P K Sbjct: 1520 NRPKFK 1525 Score = 213 bits (520), Expect = 6e-53 Identities = 213/808 (26%), Positives = 351/808 (43%), Gaps = 78/808 (9%) Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 + F ++ SG ++ R +LDRE V++ TD+ S+ + + + ++D+NDN Sbjct: 68 EYFTVNRDSGVVVLRKALDRESQDLIEVIISITDEGIAGSEPNTVSLRREIAVLDENDNP 127 Query: 148 PQFSEKTYTVSVDEDISVTDNPV-IAKIKATDADVGANSAIRYAIIGGNTQ------MQF 200 P + + Y V E V V I TD D G N+ + + + Sbjct: 128 PVYHGRPYAARVPESAHVGGLLVPPGTITITDRDGGVNADVHVECVSASRDDDVCDVFNV 187 Query: 201 SIDSLSG-----DVSLVKTLDYEQVRSYRLVIRAQDGGSP-SR--SNTTQLLINIRDVND 252 S + L+ +SL K+LDYE+ SY + + A DG S SR + +++ DV D Sbjct: 188 STEKLAEGKYDVQISLAKSLDYERRNSYLINLLAIDGASDVSRRLQARATVAVDVLDVQD 247 Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI- 311 P F + + ++ EN G++I+ V+A D D G L T+ D+D +G+ DL ++ Sbjct: 248 QPPVFLNAPYSAALPENTAAGHTILTVRARDGDTGEPRSLLLTLEDED-SGHFDLDVSRE 306 Query: 312 -DPRSG-WVYTSGQLDRE------TQAKYQLLVTATD---GGDPPRSATATXXXXXXXXX 360 D G V T+ LDRE Y V AT+ P +AT+ Sbjct: 307 GDATVGKLVTTNVSLDREDPRILQNGGIYTFQVKATELINNEIPAETATSIVTIVVTDVD 366 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPV--VTLTATDADEDNRLHYEITGGNTRG------RF 412 F + + ++ED TP+ + + +D D Y + + G F Sbjct: 367 DLMPVFNQKYFNITISEDIGKDTPLPGLNMIVSDGDVGENAKYTLALRDDPGYPGISRAF 426 Query: 413 SITSQNGRGLITV------AQPLDFKQE----RRYVLTVSATDSGGRSDTAMVQINITDA 462 + + +G + V LD+ E R+ V A + ++ V + + DA Sbjct: 427 VVGPEEAQGRVPVVVKARNVSVLDYDVEDIARRQLEFEVVALVANQVVASSRVHVRLKDA 486 Query: 463 NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522 N+++P F + Y S+ EDA IGT V A D D G ++TY+L Sbjct: 487 NDHSPEFSQSVYKLSLPEDAGIGTRFGDVFARDYDSGSFGELTYTLR--------GFGAD 538 Query: 523 QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582 +F NP+TG I+ +K LD E Y LT+ A+DGG ++ I + DVNDN+P F+ Sbjct: 539 KFATNPKTGGISVSKALDYEAQKSYSLTMEAKDGG--GRVSAVNILIELEDVNDNKPAFE 596 Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGL--NGRIHYELDPKDREEGS-FVIDPASGVI 639 Q+ YT + E A V ATDAD + NG++ Y + + F I+ +G + Sbjct: 597 QKEYTRTVREGATSFDPQMFVRATDADGPMQGNGKVTYSISSHNSMTNDVFKINRDTGEV 656 Query: 640 RTNKAL--DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD------- 690 KA+ D ++L A D GTPP S + +++ + P+F + Sbjct: 657 TMAKAVRSDDTERGIYELAIRATDAGTPPLFSETRLSVRVGVPGNQKPIFRGNYKSNLPG 716 Query: 691 --CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAEL 748 + EN+ GT + + A+DPD G ++++ Y I G N F +++ G + Sbjct: 717 PSTYRARLLENASPGTEVIRVVANDPD-GRDSLLQYHIASGAKDN-FVIDSSSG--VITV 772 Query: 749 VTMVDLDYESPRKKYELVIRA--ASPPLWNDVRVEILVT--DVNDNAPVMKDFQIIFNNY 804 LD ES +KYE+++ A + P+ + V DVN+ P + + Sbjct: 773 SPDARLDLESGGEKYEVIVYAIDSGTPVRETATTTVTVNMIDVNNKPPTFNESTYLVYVS 832 Query: 805 KDCFPVGPFGRVPAYDADVTDKLQYRIL 832 + P +V A D D L+Y I+ Sbjct: 833 ERAAIGEPVLKVAATDPDSDAYLEYSIV 860 Score = 213 bits (520), Expect = 6e-53 Identities = 214/771 (27%), Positives = 347/771 (45%), Gaps = 76/771 (9%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVL---TLKATDQDIGKNAEVEYTIE 63 + ++I VLD ND+ PV+ + Y A V E A G ++ T+ TD+D G NA+V +E Sbjct: 114 LRREIAVLDENDNPPVYHGRPYAARVPESAHVGGLLVPPGTITITDRDGGVNADVH--VE 171 Query: 64 LVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRA-SLDREKVARYTVLVKATDQ 122 V+A +D + +G+ ++ A SLD E+ Y + + A D Sbjct: 172 CVSAS--RDDDVCDVFNVSTEKL-----AEGKYDVQISLAKSLDYERRNSYLINLLAIDG 224 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 AS VS RL + AT+ V+++D D P F Y+ ++ E+ + I ++A D D G Sbjct: 225 ASDVSRRLQARATVAVDVLDVQDQPPVFLNAPYSAALPENTAA--GHTILTVRARDGDTG 282 Query: 183 ANSAIRYAIIGGNTQMQFSID-SLSGDVSLVK------TLDYEQVR------SYRLVIRA 229 ++ + ++ F +D S GD ++ K +LD E R Y ++A Sbjct: 283 EPRSLLLTLEDEDSG-HFDLDVSREGDATVGKLVTTNVSLDREDPRILQNGGIYTFQVKA 341 Query: 230 QD---GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSI--VRVQAYDA 284 + P+ + T+ + I + DV+D P F F ++SE++ + + + D Sbjct: 342 TELINNEIPAETATSIVTIVVTDVDDLMPVFNQKYFNITISEDIGKDTPLPGLNMIVSDG 401 Query: 285 DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW----VYTSGQ------LDRETQAKYQL 334 D G NA+ T + D + + P V + D E A+ QL Sbjct: 402 DVGENAKYTLALRDDPGYPGISRAFVVGPEEAQGRVPVVVKARNVSVLDYDVEDIARRQL 461 Query: 335 LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394 A++ F Y++ L ED GT + A D D Sbjct: 462 EFEVVALVANQVVASSRVHVRLKDANDHSPEFSQSVYKLSLPEDAGIGTRFGDVFARDYD 521 Query: 395 EDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT 452 + L Y + G +F+ + G I+V++ LD++ ++ Y LT+ A D GGR Sbjct: 522 SGSFGELTYTLRGFGA-DKFATNPKTGG--ISVSKALDYEAQKSYSLTMEAKDGGGRVSA 578 Query: 453 AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI--NAQITYSLSS 510 + I + D N+ P FE YT +V E A + V ATD+D + N ++TYS+SS Sbjct: 579 VNILIELEDVNDNKPAFEQKEYTRTVREGATSFDPQMFVRATDADGPMQGNGKVTYSISS 638 Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLL-DRETMSG-YLLTVTARDGGVPSLSDTTDVE 568 S + F IN TG +T K + +T G Y L + A D G P L T + Sbjct: 639 HNSMT-----NDVFKINRDTGEVTMAKAVRSDDTERGIYELAIRATDAGTPPLFSETRLS 693 Query: 569 ISVVDVNDNEPVFK---------QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619 + V + +P+F+ Y A ++E+A GT V +V A D D G + + Y Sbjct: 694 VRVGVPGNQKPIFRGNYKSNLPGPSTYRARLLENASPGTEVIRVVANDPD-GRDSLLQYH 752 Query: 620 LDPKDREEGSFVIDPASGVIRT--NKALDRESVA-THDLKAVAIDGGTP-PQSSTVIVHI 675 + ++ +FVID +SGVI + LD ES +++ AID GTP +++T V + Sbjct: 753 IASGAKD--NFVIDSSSGVITVSPDARLDLESGGEKYEVIVYAIDSGTPVRETATTTVTV 810 Query: 676 KIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 + D+N+ PP F Y+SE + IG + ++ A DPD +A + YSI Sbjct: 811 NMIDVNNKPPTFNESTYLVYVSERAAIGEPVLKVAATDPDS--DAYLEYSI 859 Score = 199 bits (485), Expect = 1e-48 Identities = 205/756 (27%), Positives = 328/756 (43%), Gaps = 64/756 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +N++D N+ P F Y V E A+ G VL + ATD D +A +EY+I V Sbjct: 810 VNMIDVNNKPPTFNESTYLVYVSERAAIGEPVLKVAATDPD--SDAYLEYSI--VEPIRA 865 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + + FRI+ +G + LD + VA +L + V D+ Sbjct: 866 VDKTGVALKNTAPYDYKTAFRINSTTGLITVNRVLDYQ-VAAVVILTVQVQDLNAVVDKE 924 Query: 131 SSTATIHVNII-----DDNDNY--PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183 + V I DDN + P +S T+ + + + A + G Sbjct: 925 RQITRVEVTIYIQAYSDDNPTFTNPGWSPNNPTIRISVPEEQPLGTTLLMLSAREPTTG- 983 Query: 184 NSAIRYAIIGGNTQMQF-SIDSLSGDVSLVKTLDYEQVR----SYRLVIRAQDGGSPSRS 238 R+ ++ + + ++ SG+V L K LDYE + +++ A+D + Sbjct: 984 YPVQRFELVREDDDEGYVNVGVQSGNVVLSKRLDYEALNQKFIQFKVRALARDYEITRKM 1043 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMT 297 + +++ ++D NDN P F ++ SV E+ ++ V+A D D E+ Sbjct: 1044 SEANVIVEVQDTNDNNPVFAQKDYKISVLESEKPSKIVLNVKATDMDSSNTEQEVRRGYG 1103 Query: 298 DKDYT--GNVDLPITIDPRSG--WVYTSGQLDRETQAKYQLLVTATD---GGDPPRSATA 350 + Y+ G ++P +G + T+ LDRE Q+ + V A+D GG RS A Sbjct: 1104 EVRYSLIGENANMFEVEPITGNIQIATNTTLDREKQSVLRFYVVASDMPQGGAEQRSTRA 1163 Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITG-GN 407 F Y + E+ P G VV +TATD DED ++YEI G Sbjct: 1164 LVTVDVLDVNDNAPTFEQEAYTAVIPENAPSGVSVVNITATDPDEDKGGVINYEIIDEGE 1223 Query: 408 TRGRFSITSQNGRGLITVAQPLDFK-QERRYVLTVSATDSGG---RSDTAM-VQINITDA 462 G F I + G I A+ L K + Y++ + D G SD + + I + Sbjct: 1224 ASGLFEIDHKTGE--IYSARALTGKGRTEPYIMRIRGEDGGEPELYSDVILTLYIGDVVS 1281 Query: 463 NNYAPVF--ENAPYTASVFEDAPIGTTVLVVSATDSDVG--INAQITYSLSSEISNEAVA 518 N+ P+F A + E++ IG+ V V A+D D N +IT+ + + Sbjct: 1282 NDGVPLFIRPTLEEVAYISENSTIGSPVFQVVASDPDDPNLPNGKITFKF---LEDGNFG 1338 Query: 519 HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578 F IN +TG ITT KLLDRE Y L + A+D G P T +++ V D++D++ Sbjct: 1339 KDASAFRINSETGLITTRKLLDREAKDSYTLILVAQDLGNPPQQATRVLQVIVNDIDDHK 1398 Query: 579 PVFKQQL----YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634 P FK+ L ++E+ +G V + A D D+G NG I Y + E G F+++ Sbjct: 1399 PHFKRNLDSPPVELAVLEETPIGAKVGVIEAIDEDIGENGMIDYAI-VYGNEAGLFLVER 1457 Query: 635 A---SGVIRTNKALDRESVATHDLKAVAI------DGGTPPQ------SSTVIVHIKIED 679 S VIR+N LDRE A H L + G P+ S V +K+ D Sbjct: 1458 LENNSAVIRSNGRLDRER-ADHHLLTIKCFPYSTKKGDIVPKPYNRQDPSERQVLVKVLD 1516 Query: 680 INDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 I+D+ P F+ + +T + N PI T++ + A D D Sbjct: 1517 IDDNRPKFKKENVTLGVRLNVPIDTSLITLEALDAD 1552 Score = 140 bits (340), Expect = 4e-31 Identities = 179/702 (25%), Positives = 306/702 (43%), Gaps = 90/702 (12%) Query: 250 VNDNAPRFYTS--LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 V + AP F + + +VSE P G + ++ D + ++L Y+++ + +T N D Sbjct: 20 VINRAPHFVQGGDMARLAVSEGTPPGAPVYTLKGEDPE---GSKLHYSISGEYFTVNRD- 75 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATD---GGDPPRSATATXXXXXXXXXXXXX 364 SG V LDRE+Q +++++ TD G P + + Sbjct: 76 -------SGVVVLRKALDRESQDLIEVIISITDEGIAGSEPNTVSLRREIAVLDENDNPP 128 Query: 365 XFMPGQYEVELAEDE-------PPGTPVVTLTATDADEDNRLHYEITGGNTRGR----FS 413 + Y + E PPGT +T+T D + +H E + F+ Sbjct: 129 VYHGRPYAARVPESAHVGGLLVPPGT--ITITDRDGGVNADVHVECVSASRDDDVCDVFN 186 Query: 414 ITSQN-GRGL----ITVAQPLDFKQERRYVLTVSATDSGGRSDT-------AMVQINITD 461 ++++ G I++A+ LD+++ Y++ + A D G SD A V +++ D Sbjct: 187 VSTEKLAEGKYDVQISLAKSLDYERRNSYLINLLAID--GASDVSRRLQARATVAVDVLD 244 Query: 462 ANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521 + PVF NAPY+A++ E+ G T+L V A D D G + +L E S Sbjct: 245 VQDQPPVFLNAPYSAALPENTAAGHTILTVRARDGDTGEPRSLLLTLEDEDSGHFDLDVS 304 Query: 522 QQFVINPQTG-AITTNKLLDRE----TMSGYLLTVTAR-----DGGVPSLSDTTDVEISV 571 ++ + G +TTN LDRE +G + T + + +P+ + T+ V I V Sbjct: 305 REG--DATVGKLVTTNVSLDREDPRILQNGGIYTFQVKATELINNEIPAETATSIVTIVV 362 Query: 572 VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG--ATDADVGLNGRIHYELDPKDREEG- 628 DV+D PVF Q+ + I ED T + + +D DVG N + L G Sbjct: 363 TDVDDLMPVFNQKYFNITISEDIGKDTPLPGLNMIVSDGDVGENAKYTLALRDDPGYPGI 422 Query: 629 --SFVIDP--ASG----VIRTNKA----LDRESVATHDL--KAVAIDGGTPPQSSTVIVH 674 +FV+ P A G V++ D E +A L + VA+ SS VH Sbjct: 423 SRAFVVGPEEAQGRVPVVVKARNVSVLDYDVEDIARRQLEFEVVALVANQVVASSR--VH 480 Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734 ++++D ND P F + E++ IGT G++ A D D G + Y+++ G ++ Sbjct: 481 VRLKDANDHSPEFSQSVYKLSLPEDAGIGTRFGDVFARDYDSGSFGELTYTLR-GFGADK 539 Query: 735 FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAPV 793 F+ + G + LDYE+ +K Y L + A + V + I + DVNDN P Sbjct: 540 FATNPKTGG----ISVSKALDYEA-QKSYSLTMEAKDGGGRVSAVNILIELEDVNDNKPA 594 Query: 794 MKDFQIIFNNYKDCFPVGPFGRVPAYDAD----VTDKLQYRILSGNNA--NLILLNETTG 847 + + + P V A DAD K+ Y I S N+ ++ +N TG Sbjct: 595 FEQKEYTRTVREGATSFDPQMFVRATDADGPMQGNGKVTYSISSHNSMTNDVFKINRDTG 654 Query: 848 SMTLSPQLNTNVPKLATMEVSV--TD-GVNEIKAMMQLSVRL 886 +T++ + ++ + E+++ TD G + + +LSVR+ Sbjct: 655 EVTMAKAVRSDDTERGIYELAIRATDAGTPPLFSETRLSVRV 696 Score = 97.1 bits (231), Expect = 6e-18 Identities = 77/288 (26%), Positives = 138/288 (47%), Gaps = 31/288 (10%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 FRI+ +G + TR LDRE YT+++ A D +P +T + V + D +D+ P Sbjct: 1344 FRINSETGLITTRKLLDREAKDSYTLILVAQDLGNPPQQ---ATRVLQVIVNDIDDHKPH 1400 Query: 150 FSEKTYTVSVDEDISVTDNPVIAK---IKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206 F + V+ + + + P+ AK I+A D D+G N I YAI+ GN F ++ L Sbjct: 1401 FKRNLDSPPVELAV-LEETPIGAKVGVIEAIDEDIGENGMIDYAIVYGNEAGLFLVERLE 1459 Query: 207 GDVSLVKT---LDYEQVRSYRLVIRAQDGGS------PSRSNTT-----QLLINIRDVND 252 + +++++ LD E+ + L I+ + P N Q+L+ + D++D Sbjct: 1460 NNSAVIRSNGRLDRERADHHLLTIKCFPYSTKKGDIVPKPYNRQDPSERQVLVKVLDIDD 1519 Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD------ 306 N P+F V NVPI S++ ++A DAD + Y+M +T VD Sbjct: 1520 NRPKFKKENVTLGVRLNVPIDTSLITLEALDADSDA-LPINYSMGKASFTSLVDPSMSRR 1578 Query: 307 -LP--ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 +P ++++ ++G + T+G + +++V+A + P R T Sbjct: 1579 KIPSHLSLNSQTGELRTTGSMSSYADGYMEIIVSANNSVTPARETNIT 1626 >UniRef50_Q4SVM8 Cluster: Chromosome 1 SCAF13750, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1 SCAF13750, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 2845 Score = 229 bits (560), Expect = 8e-58 Identities = 170/580 (29%), Positives = 278/580 (47%), Gaps = 25/580 (4%) Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ-DGGSPSRS 238 DVG + ++ G Q F ++ G +S+ + +D E++ + A + Sbjct: 1820 DVGRLTDRNLRLLSGTKQDLFKVNPSDGVLSVKRRVDREELCAKMAPCVANLKAVVENPL 1879 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 Q++I I DVNDNAP+F + V E+ +G A+D + G+N+ TY + + Sbjct: 1880 EMHQVIIEILDVNDNAPKFPEENYTLEVLESAMVGSRFQIEGAHDLEVGINSLQTYKINN 1939 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358 Y D + ++ QLDRE A++ L VTA DGG P +S Sbjct: 1940 NQYFRVETEEFGEDGKVPFLILHRQLDREQTAQHWLKVTALDGGKPIKSGNLNITVIVSD 1999 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITG---GNTRGRFS 413 +Y V + E+ P GT ++T+ A+D DE ++ + Y + G F+ Sbjct: 2000 INDNPPVCDKQKYVVTVKENAPEGTFLLTVNASDPDEGMNSAIEYSLRSKLRGIHSDPFN 2059 Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFEN 471 + S G+ +TV LD+++++ Y + V A D G S V + + D N+ P E Sbjct: 2060 LDSTTGK--LTVKAGLDYEEKQVYEIKVLAADKGSVSLSTHCNVVVRVEDVNDNPPEIEI 2117 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 ++S+ EDAP GT V ++ TD D G+N Q+ S+ + + + D + Sbjct: 2118 TSLSSSIPEDAPPGTVVALMGVTDRDSGVNGQVICSVPAHLPFDLKPSPDGH------SY 2171 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 ++ T LD+E+ Y + +TA+D G P+LS T + + V+DVNDN P+F + YT + Sbjct: 2172 SLVTKDYLDKESTHMYDIQITAKDLGSPALSSTKVIHVDVLDVNDNRPLFSESPYTFYVP 2231 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFV-IDPASGVIRTNKALDRES 649 E+ G+SV V A+D D G N + Y L +D SF+ I+ A+G I K D E+ Sbjct: 2232 ENNKAGSSVFTVSASDVDSGQNAALSYSLIRNQDLTITSFLNINEANGTISALKTFDFET 2291 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF----ESDCLTFYISE---NSPI 702 + T + VA D G+P SS V V + I D ND+ PV S+ + E N Sbjct: 2292 LKTFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNA 2351 Query: 703 GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 G + ++RA+D D G N + ++++ D + F L+ G Sbjct: 2352 GHLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTG 2391 Score = 223 bits (544), Expect = 7e-56 Identities = 178/607 (29%), Positives = 270/607 (44%), Gaps = 28/607 (4%) Query: 87 QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146 QD+F+++ G L + +DRE++ A +A V + L I + I+D NDN Sbjct: 1837 QDLFKVNPSDGVLSVKRRVDREELCAKMAPCVANLKAV-VENPLEMHQVI-IEILDVNDN 1894 Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206 P+F E+ YT+ V E V I A D +VG NS Y I N + + Sbjct: 1895 APKFPEENYTLEVLESAMVGSRFQIEG--AHDLEVGINSLQTYKI-NNNQYFRVETEEFG 1951 Query: 207 GD-----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261 D + L + LD EQ + L + A DGG P +S + + + D+NDN P Sbjct: 1952 EDGKVPFLILHRQLDREQTAQHWLKVTALDGGKPIKSGNLNITVIVSDINDNPPVCDKQK 2011 Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321 + +V EN P G ++ V A D DEG+N+ + Y++ K G P +D +G + Sbjct: 2012 YVVTVKENAPEGTFLLTVNASDPDEGMNSAIEYSLRSK-LRGIHSDPFNLDSTTGKLTVK 2070 Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381 LD E + Y++ V A D G S + ED PP Sbjct: 2071 AGLDYEEKQVYEIKVLAADKGSVSLSTHCNVVVRVEDVNDNPPEIEITSLSSSIPEDAPP 2130 Query: 382 GTPVVTLTATDADEDNRLHYEITGGNTRGRFSI-TSQNGRGLITVAQP-LDFKQERRYVL 439 GT V + TD D I F + S +G V + LD + Y + Sbjct: 2131 GTVVALMGVTDRDSGVN-GQVICSVPAHLPFDLKPSPDGHSYSLVTKDYLDKESTHMYDI 2189 Query: 440 TVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497 ++A D G S T ++ +++ D N+ P+F +PYT V E+ G++V VSA+D D Sbjct: 2190 QITAKDLGSPALSSTKVIHVDVLDVNDNRPLFSESPYTFYVPENNKAGSSVFTVSASDVD 2249 Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG 557 G NA ++YSL I N+ + IN G I+ K D ET+ + V A D G Sbjct: 2250 SGQNAALSYSL---IRNQDLT-ITSFLNINEANGTISALKTFDFETLKTFQFQVVASDSG 2305 Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYT-------ANIMEDALVGTSVSQVGATDADV 610 PSLS V++ ++D NDN PV + + I + G V++V A DAD+ Sbjct: 2306 SPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVRAYDADI 2365 Query: 611 GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST 670 G NG + + L + + F +D +G IRT ++ A H L + D G S+T Sbjct: 2366 GYNGWLLFALQ-EVSDHSLFGLDRYTGQIRTLRSFTETDEAEHKLVILVKDNGNVSLSAT 2424 Query: 671 VIVHIKI 677 V +K+ Sbjct: 2425 ATVLVKL 2431 Score = 199 bits (486), Expect = 8e-49 Identities = 160/558 (28%), Positives = 254/558 (45%), Gaps = 30/558 (5%) Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195 I V I D NDN P F T + + E SV + + A D DVG+NS Y + + Sbjct: 1119 IEVEITDINDNAPHFRRGTMHLDISESSSVGER--FSLNNAADPDVGSNSVKDYHL---S 1173 Query: 196 TQMQFSIDSLSG-------DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 FSI+ +G D+ L K LD E + L++ A DGG P+R+ T +++ + Sbjct: 1174 ASEHFSINIQTGRDGTKFADLILTKALDREMQAVHNLILTAVDGGVPTRTGTASIVVRVL 1233 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NVDL 307 DVNDNAP F + V EN PIG ++++ A D DEG N+++ Y+ + YT Sbjct: 1234 DVNDNAPSFDREKYVVDVMENSPIGSLVLKLNATDLDEGSNSDIVYSYS--LYTSERTQQ 1291 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 ++P +G + ++ E +++ V A+D G S Sbjct: 1292 VFHLNPENGEIRVREMINYEDLKLFEMEVIASDKGPNLLSGQCKLTIQVTDMNDNHPEIS 1351 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 ++ + E+ T + ++ +D D DN + + +S N L+ V+ Sbjct: 1352 IKSFQSPVKENIDVETVIAVVSVSDKDSGDNGVVDLHIPDKMPFKLRQSSDNYYELV-VS 1410 Query: 427 QPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 +PLD ++ Y +T + TD G SD + + + D N+ P F + YT V E+ Sbjct: 1411 EPLDREKVPEYDITFTVTDRGSPPLSDNETMTLELLDVNDNVPRFPQSFYTIRVTENNAP 1470 Query: 485 GTTVLVVSATDSDVGINAQITY-SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 G + ++A D D+ N + Y L EI+N +++ F INP+ G + K D E Sbjct: 1471 GALLSSLTAFDPDLHENQYLVYFILEKEIANTSMS---MLFSINPENGNLYALKTFDYEI 1527 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT-ANIMEDAL-----VG 597 +L + ARD G P LS V I +VD NDN PV +++E+ + G Sbjct: 1528 EKEFLFHIEARDSGSPPLSSNVTVHIVIVDQNDNAPVIVSPWRAQGSVVEEKIPRSTDKG 1587 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 + V++V A D D N RI Y+L + + F +D +G IRT + L Sbjct: 1588 SLVAKVIALDVDSVHNSRITYQL-LQVTDATLFSLDQYNGEIRTMRMFSYRDPRHQRLVV 1646 Query: 658 VAIDGGTPPQSSTVIVHI 675 VA D G P S+TV + + Sbjct: 1647 VAKDNGDPALSATVTIKL 1664 Score = 196 bits (477), Expect = 1e-47 Identities = 125/376 (33%), Positives = 198/376 (52%), Gaps = 21/376 (5%) Query: 429 LDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD +Q ++ L V+A D G +S + + ++D N+ PV + Y +V E+AP GT Sbjct: 1965 LDREQTAQHWLKVTALDGGKPIKSGNLNITVIVSDINDNPPVCDKQKYVVTVKENAPEGT 2024 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 +L V+A+D D G+N+ I YSL S++ H F ++ TG +T LD E Sbjct: 2025 FLLTVNASDPDEGMNSAIEYSLRSKLRGI----HSDPFNLDSTTGKLTVKAGLDYEEKQV 2080 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y + V A D G SLS +V + V DVNDN P + +++I EDA GT V+ +G T Sbjct: 2081 YEIKVLAADKGSVSLSTHCNVVVRVEDVNDNPPEIEITSLSSSIPEDAPPGTVVALMGVT 2140 Query: 607 DADVGLNGRI------HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 D D G+NG++ H D K +G S + T LD+ES +D++ A Sbjct: 2141 DRDSGVNGQVICSVPAHLPFDLKPSPDGH------SYSLVTKDYLDKESTHMYDIQITAK 2194 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 D G+P SST ++H+ + D+ND+ P+F TFY+ EN+ G+++ + A D D G NA Sbjct: 2195 DLGSPALSSTKVIHVDVLDVNDNRPLFSESPYTFYVPENNKAGSSVFTVSASDVDSGQNA 2254 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIR-AASPPLWNDV 778 + YS+ D S + + D+E+ + ++++V + SP L ++V Sbjct: 2255 ALSYSLIRNQDLTITSF-LNINEANGTISALKTFDFETLKTFQFQVVASDSGSPSLSSNV 2313 Query: 779 RVEILVTDVNDNAPVM 794 V++ + D NDNAPV+ Sbjct: 2314 TVKVFILDQNDNAPVI 2329 Score = 190 bits (463), Expect = 5e-46 Identities = 163/586 (27%), Positives = 259/586 (44%), Gaps = 59/586 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ + D ND++P F + E +S G A D D+G N+ +Y + + Sbjct: 1120 EVEITDINDNAPHFRRGTMHLDISESSSVGERFSLNNAADPDVGSNSVKDYHLSASEHFS 1179 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 +N + + +LT+A LDRE A + +++ A D P Sbjct: 1180 INIQTGRDGTKF--------------ADLILTKA-LDREMQAVHNLILTAVDGGVPTR-- 1222 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + TA+I V ++D NDN P F + Y V V E+ + ++ K+ ATD D G+NS I Y Sbjct: 1223 -TGTASIVVRVLDVNDNAPSFDREKYVVDVMENSPI--GSLVLKLNATDLDEGSNSDIVY 1279 Query: 190 A---IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 + TQ F ++ +G++ + + ++YE ++ + + + A D G S +L I Sbjct: 1280 SYSLYTSERTQQVFHLNPENGEIRVREMINYEDLKLFEMEVIASDKGPNLLSGQCKLTIQ 1339 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + D+NDN P FQ V EN+ + I V D D G N + + DK Sbjct: 1340 VTDMNDNHPEISIKSFQSPVKENIDVETVIAVVSVSDKDSGDNGVVDLHIPDK------- 1392 Query: 307 LPITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 +P + S Y S LDRE +Y + T TD G PP S T Sbjct: 1393 MPFKLRQSSDNYYELVVSEPLDREKVPEYDITFTVTDRGSPPLSDNETMTLELLDVNDNV 1452 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHY-----EITGGNTRGRFSITS 416 F Y + + E+ PG + +LTA D D E+ L Y EI + FSI Sbjct: 1453 PRFPQSFYTIRVTENNAPGALLSSLTAFDPDLHENQYLVYFILEKEIANTSMSMLFSINP 1512 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPY 474 +NG + + D++ E+ ++ + A DSG S V I I D N+ APV +P+ Sbjct: 1513 ENGN--LYALKTFDYEIEKEFLFHIEARDSGSPPLSSNVTVHIVIVDQNDNAPVIV-SPW 1569 Query: 475 TA--SVFED-----APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527 A SV E+ G+ V V A D D N++ITY L ++++ + F ++ Sbjct: 1570 RAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQL-LQVTDATL------FSLD 1622 Query: 528 PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 G I T ++ L V A+D G P+LS T +++S V+ Sbjct: 1623 QYNGEIRTMRMFSYRDPRHQRLVVVAKDNGDPALSATVTIKLSTVE 1668 Score = 189 bits (461), Expect = 8e-46 Identities = 161/586 (27%), Positives = 263/586 (44%), Gaps = 46/586 (7%) Query: 4 PFCIHQQI-NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 P +HQ I +LD ND++P F + Y V E A G+ A D ++G N+ Y I Sbjct: 1878 PLEMHQVIIEILDVNDNAPKFPEENYTLEVLESAMVGSRFQIEGAHDLEVGINSLQTYKI 1937 Query: 63 ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122 + E+ F DG+ L+ LDRE+ A++ + V A D Sbjct: 1938 NNNQYFRVETEE---------------FGEDGKVPFLILHRQLDREQTAQHWLKVTALDG 1982 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 P+ S I V + D NDN P ++ Y V+V E+ + + + A+D D G Sbjct: 1983 GKPIK---SGNLNITVIVSDINDNPPVCDKQKYVVTVKEN--APEGTFLLTVNASDPDEG 2037 Query: 183 ANSAIRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239 NSAI Y++ + G F++DS +G +++ LDYE+ + Y + + A D GS S S Sbjct: 2038 MNSAIEYSLRSKLRGIHSDPFNLDSTTGKLTVKAGLDYEEKQVYEIKVLAADKGSVSLST 2097 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 +++ + DVNDN P + S+ E+ P G + + D D GVN ++ ++ Sbjct: 2098 HCNVVVRVEDVNDNPPEIEITSLSSSIPEDAPPGTVVALMGVTDRDSGVNGQVICSVPAH 2157 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 DL + D S + T LD+E+ Y + +TA D G P S+T Sbjct: 2158 ---LPFDLKPSPDGHSYSLVTKDYLDKESTHMYDIQITAKDLGSPALSSTKVIHVDVLDV 2214 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQ 417 F Y + E+ G+ V T++A+D D ++ L Y + S + Sbjct: 2215 NDNRPLFSESPYTFYVPENNKAGSSVFTVSASDVDSGQNAALSYSLIRNQDLTITSFLNI 2274 Query: 418 N-GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVF---EN 471 N G I+ + DF+ + + V A+DSG S V++ I D N+ APV + Sbjct: 2275 NEANGTISALKTFDFETLKTFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVS 2334 Query: 472 APYTASVFEDAP----IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527 + +A E+ P G V V A D+D+G N + ++L E+S+ ++ F ++ Sbjct: 2335 SNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFAL-QEVSDHSL------FGLD 2387 Query: 528 PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 TG I T + + + L + +D G SLS T V + +V+ Sbjct: 2388 RYTGQIRTLRSFTETDEAEHKLVILVKDNGNVSLSATATVLVKLVE 2433 Score = 182 bits (442), Expect = 2e-43 Identities = 148/578 (25%), Positives = 258/578 (44%), Gaps = 29/578 (5%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGR--- 420 F G ++++E G A D D ++ Y ++ FSI Q GR Sbjct: 1133 FRRGTMHLDISESSSVGERFSLNNAADPDVGSNSVKDYHLSASE---HFSINIQTGRDGT 1189 Query: 421 --GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTA 476 + + + LD + + + L ++A D G R+ TA + + + D N+ AP F+ Y Sbjct: 1190 KFADLILTKALDREMQAVHNLILTAVDGGVPTRTGTASIVVRVLDVNDNAPSFDREKYVV 1249 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 V E++PIG+ VL ++ATD D G N+ I YS S S Q F +NP+ G I Sbjct: 1250 DVMENSPIGSLVLKLNATDLDEGSNSDIVYSYSLYTSERT----QQVFHLNPENGEIRVR 1305 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 ++++ E + + + V A D G LS + I V D+NDN P + + + + E+ V Sbjct: 1306 EMINYEDLKLFEMEVIASDKGPNLLSGQCKLTIQVTDMNDNHPEISIKSFQSPVKENIDV 1365 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 T ++ V +D D G NG + + K + D ++ ++ LDRE V +D+ Sbjct: 1366 ETVIAVVSVSDKDSGDNGVVDLHIPDKMPFKLRQSSDNYYELV-VSEPLDREKVPEYDIT 1424 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 D G+PP S + +++ D+ND+ P F T ++EN+ G + + A DPD Sbjct: 1425 FTVTDRGSPPLSDNETMTLELLDVNDNVPRFPQSFYTIRVTENNAPGALLSSLTAFDPDL 1484 Query: 717 GPNAVVHYSIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIR-AASPP 773 N + Y I + +N S S+ + L + DYE ++ + + R + SPP Sbjct: 1485 HENQYLVYFILEKEIANTSMSMLFSINPENGNLYALKTFDYEIEKEFLFHIEARDSGSPP 1544 Query: 774 LWNDVRVEILVTDVNDNAPVM-----KDFQIIFNNYKDCFPVGPF-GRVPAYDADV--TD 825 L ++V V I++ D NDNAPV+ ++ G +V A D D Sbjct: 1545 LSSNVTVHIVIVDQNDNAPVIVSPWRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNS 1604 Query: 826 KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVR 885 ++ Y++L +A L L++ G + + P+ + V D + ++++ Sbjct: 1605 RITYQLLQVTDATLFSLDQYNGEIRTMRMFSYRDPRHQRLVVVAKDN-GDPALSATVTIK 1663 Query: 886 LITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAI 923 L T E + + + S L + + GL ++ Sbjct: 1664 LSTVETAVKAYSDMTEVPLEYDIFSDLNLYLVIGLGSV 1701 Score = 173 bits (422), Expect = 4e-41 Identities = 127/427 (29%), Positives = 198/427 (46%), Gaps = 17/427 (3%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 V I I D N+ AP F YT V E A +G+ + A D +VGIN+ TY +++ N Sbjct: 1884 VIIEILDVNDNAPKFPEENYTLEVLESAMVGSRFQIEGAHDLEVGINSLQTYKINN---N 1940 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 + ++F + + + ++ LDRE + + L VTA DGG P S ++ + V D+ Sbjct: 1941 QYFRVETEEFGEDGKVPFLILHRQLDREQTAQHWLKVTALDGGKPIKSGNLNITVIVSDI 2000 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR--EEGSFVI 632 NDN PV +Q Y + E+A GT + V A+D D G+N I Y L K R F + Sbjct: 2001 NDNPPVCDKQKYVVTVKENAPEGTFLLTVNASDPDEGMNSAIEYSLRSKLRGIHSDPFNL 2060 Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692 D +G + LD E +++K +A D G+ S+ V +++ED+ND+PP E L Sbjct: 2061 DSTTGKLTVKAGLDYEEKQVYEIKVLAADKGSVSLSTHCNVVVRVEDVNDNPPEIEITSL 2120 Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752 + I E++P GT + + D D G N V S+ F L+ LVT Sbjct: 2121 SSSIPEDAPPGTVVALMGVTDRDSGVNGQVICSVPA---HLPFDLKPSPDGHSYSLVTKD 2177 Query: 753 DLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809 LD ES Y++ I A SP L + + + V DVNDN P+ + F ++ Sbjct: 2178 YLDKESTH-MYDIQITAKDLGSPALSSTKVIHVDVLDVNDNRPLFSESPYTFYVPENNKA 2236 Query: 810 VGPFGRVPAYDADVTDK--LQYRILSGNN---ANLILLNETTGSMTLSPQLNTNVPKLAT 864 V A D D L Y ++ + + + +NE G+++ + K Sbjct: 2237 GSSVFTVSASDVDSGQNAALSYSLIRNQDLTITSFLNINEANGTISALKTFDFETLKTFQ 2296 Query: 865 MEVSVTD 871 +V +D Sbjct: 2297 FQVVASD 2303 Score = 163 bits (396), Expect = 6e-38 Identities = 178/710 (25%), Positives = 295/710 (41%), Gaps = 83/710 (11%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ + D ND++P F + E +S G A D D+G N+ +Y + + Sbjct: 321 EVEITDINDNAPHFRRGTMHLDISESSSVGERFSLNNAADPDVGSNSVKDYHLSASEHFS 380 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 +N + + +LT+A LDRE A + +++ A D P Sbjct: 381 INIQTGRDGTKF--------------ADLILTKA-LDREMQAVHNLILTAVDGGVP---- 421 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 T T D NDN+P+ S K++ V E+I V VIA + +D D G N + Sbjct: 422 ---TRT------DMNDNHPEISIKSFQSPVKENIDV--ETVIAVVSVSDKDSGDNGVVDL 470 Query: 190 AIIGGNTQMQFSIDSLSG---DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 I +M F + S ++ + + LD E+V Y + D GSP S+ + + Sbjct: 471 HI---PDKMPFKLRQSSDNYYELVVSEPLDREKVPEYDITFTVTDRGSPPLSDNETMTLE 527 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NV 305 + DVNDN PRF S + V+EN G + + A+D D N L Y + +K+ ++ Sbjct: 528 LLDVNDNVPRFPQSFYTIRVTENNAPGALLSSLTAFDPDLHENQYLVYFILEKEIANTSM 587 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 + +I+P +G +Y D E + ++ + A D G PP S+ T Sbjct: 588 SMLFSINPENGNLYALKTFDYEIEKEFLFHIEARDSGSPPLSSNVTVHIVIVDQNDNAPV 647 Query: 366 FM-PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLIT 424 + P + + E P V+ L D+ ++R+ Y++ FS+ NG I Sbjct: 648 IVSPWRAQGLCGGGEDP--QVIALD-VDSVHNSRITYKLLQVTDATLFSLDQYNGE--IR 702 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN---APYTASVFED 481 + ++ R L V A D+G + +A V I ++ + + P +F D Sbjct: 703 TMRMFSYRDPRHQRLVVVAKDNGDPALSATVTIKLSTVETAVKAYSDMTEVPLEYDIFSD 762 Query: 482 ----APIGTTVLVVSATDS----DVGINAQITYSLSSEISNEAVAH-------------- 519 IG + V+SA S V T + S+ +SN+A + Sbjct: 763 LNLYLVIGAGLGVLSAAHSPSWNSVISERNSTIADSTLVSNDAYWYSLFLAETRKGKLVV 822 Query: 520 -----HDQQFVINP---QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571 +++++ + G + K D E +L + ARD G P LS V I + Sbjct: 823 RQPVPKGSRYIVSSIPRENGNLYALKTFDYEIEKEFLFHIEARDSGSPPLSSNVTVHIVI 882 Query: 572 VDVNDNEPVFKQQLYT-ANIMEDAL-----VGTSVSQVGATDADVGLNGRIHYELDPKDR 625 VD NDN PV +++E+ + G+ V++V A D D N RI Y+L + Sbjct: 883 VDQNDNAPVIVSPWRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQL-LQVT 941 Query: 626 EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675 + F +D +G IRT + L VA D G P S+TV + + Sbjct: 942 DATLFSLDQYNGEIRTMRMFSYRDPRHQRLVVVAKDNGDPALSATVTIKL 991 Score = 153 bits (370), Expect = 9e-35 Identities = 235/982 (23%), Positives = 387/982 (39%), Gaps = 104/982 (10%) Query: 11 INVLDCNDHSPVF------EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIEL 64 I ++D ND++PV + E + G+ V + A D D N+ + Y + Sbjct: 82 IVIVDQNDNAPVIVSPWRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQLLQ 141 Query: 65 VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS 124 VT TL D +R D R L+ A + + TV +K + + Sbjct: 142 VTDATLFSLDQYNGEIRTMRMFS--YR-DPRHQRLVVVAKDNGDPALSATVTIKLSTVET 198 Query: 125 PVSDRLSSTAT-IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183 V T + +I D + Y + + + I VT ++ K + A A Sbjct: 199 AVKAYSDMTEVPLEYDIFSDLNLYLVIGLGSVSFLLLITILVT---IVIKCQKPKASKAA 255 Query: 184 NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT-- 241 A R ++I +S D +L + R +LV+R Q SR + T Sbjct: 256 -PACRNSVISERNSTIADSTLVSNDAYWY-SLFLAETRKGKLVVR-QPVPKGSRLDATIE 312 Query: 242 ------QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295 + + I D+NDNAP F +SE+ +G A D D G N+ Y Sbjct: 313 NPVRMFNIEVEITDINDNAPHFRRGTMHLDISESSSVGERFSLNNAADPDVGSNSVKDYH 372 Query: 296 MTDKDYTG-NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354 ++ ++ N+ + + T LDRE QA + L++TA DGG P R+ Sbjct: 373 LSASEHFSINIQTGRDGTKFADLILTKA-LDREMQAVHNLILTAVDGGVPTRTDMNDNHP 431 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFS 413 ++ + E+ T + ++ +D D DN + + Sbjct: 432 EISIKS----------FQSPVKENIDVETVIAVVSVSDKDSGDNGVVDLHIPDKMPFKLR 481 Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFEN 471 +S N L+ V++PLD ++ Y +T + TD G SD + + + D N+ P F Sbjct: 482 QSSDNYYELV-VSEPLDREKVPEYDITFTVTDRGSPPLSDNETMTLELLDVNDNVPRFPQ 540 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS-LSSEISNEAVAHHDQQFVINPQT 530 + YT V E+ G + ++A D D+ N + Y L EI+N +++ F INP+ Sbjct: 541 SFYTIRVTENNAPGALLSSLTAFDPDLHENQYLVYFILEKEIANTSMS---MLFSINPEN 597 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590 G + K D E +L + ARD G P LS V I +VD NDN PV + Sbjct: 598 GNLYALKTFDYEIEKEFLFHIEARDSGSPPLSSNVTVHIVIVDQNDNAPVIVSPWRAQGL 657 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650 G QV A D D N RI Y+L + + F +D +G IRT + Sbjct: 658 CG----GGEDPQVIALDVDSVHNSRITYKL-LQVTDATLFSLDQYNGEIRTMRMFSYRDP 712 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKI--------EDINDSPPVFE--SDCLTFYISENS 700 L VA D G P S+TV + + D+ + P ++ SD L Y+ Sbjct: 713 RHQRLVVVAKDNGDPALSATVTIKLSTVETAVKAYSDMTEVPLEYDIFSD-LNLYLV--- 768 Query: 701 PIGTTIGEIRA-HDPDEGP-----NAVVHYSIKGGDDSNSFSL---ETRQGS-------- 743 IG +G + A H P N+ + S +D+ +SL ETR+G Sbjct: 769 -IGAGLGVLSAAHSPSWNSVISERNSTIADSTLVSNDAYWYSLFLAETRKGKLVVRQPVP 827 Query: 744 ------------DKAELVTMVDLDYESPRK-KYELVIR-AASPPLWNDVRVEILVTDVND 789 + L + DYE ++ + + R + SPPL ++V V I++ D ND Sbjct: 828 KGSRYIVSSIPRENGNLYALKTFDYEIEKEFLFHIEARDSGSPPLSSNVTVHIVIVDQND 887 Query: 790 NAPVM-----KDFQIIFNNYKDCFPVGPF-GRVPAYDADV--TDKLQYRILSGNNANLIL 841 NAPV+ ++ G +V A D D ++ Y++L +A L Sbjct: 888 NAPVIVSPWRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQLLQVTDATLFS 947 Query: 842 LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLN 901 L++ G + + P+ + V D + ++++L T E + + + Sbjct: 948 LDQYNGEIRTMRMFSYRDPRHQRLVVVAKDN-GDPALSATVTIKLSTVETAVKAYSDMTE 1006 Query: 902 DMTAEQFLSPLLGFFIDGLAAI 923 S L + + GL ++ Sbjct: 1007 VPLEYDIFSDLNLYLVIGLGSV 1028 Score = 151 bits (366), Expect = 3e-34 Identities = 93/279 (33%), Positives = 144/279 (51%), Gaps = 15/279 (5%) Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVNDNEPVFK 582 F +NP G ++ + +DRE + + A V + + V I ++DVNDN P F Sbjct: 1840 FKVNPSDGVLSVKRRVDREELCAKMAPCVANLKAVVENPLEMHQVIIEILDVNDNAPKFP 1899 Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR---EEGSFVIDPASGVI 639 ++ YT ++E A+VG+ GA D +VG+N Y+++ E F D + Sbjct: 1900 EENYTLEVLESAMVGSRFQIEGAHDLEVGINSLQTYKINNNQYFRVETEEFGEDGKVPFL 1959 Query: 640 RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699 ++ LDRE A H LK A+DGG P +S + + + + DIND+PPV + + EN Sbjct: 1960 ILHRQLDREQTAQHWLKVTALDGGKPIKSGNLNITVIVSDINDNPPVCDKQKYVVTVKEN 2019 Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKG---GDDSNSFSLETRQGSDKAELVTMVDLDY 756 +P GT + + A DPDEG N+ + YS++ G S+ F+L++ G +L LDY Sbjct: 2020 APEGTFLLTVNASDPDEGMNSAIEYSLRSKLRGIHSDPFNLDSTTG----KLTVKAGLDY 2075 Query: 757 ESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAP 792 E ++ YE+ + AA S L V + V DVNDN P Sbjct: 2076 EE-KQVYEIKVLAADKGSVSLSTHCNVVVRVEDVNDNPP 2113 Score = 131 bits (317), Expect = 2e-28 Identities = 137/534 (25%), Positives = 228/534 (42%), Gaps = 58/534 (10%) Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM-P 368 +I +G +Y D E + ++ + A D G PP S+ T + P Sbjct: 836 SIPRENGNLYALKTFDYEIEKEFLFHIEARDSGSPPLSSNVTVHIVIVDQNDNAPVIVSP 895 Query: 369 GQYEVELAEDEPP-----GTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRG 421 + + + E++ P G+ V + A D D ++R+ Y++ FS+ NG Sbjct: 896 WRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQLLQVTDATLFSLDQYNGE- 954 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN---APYTASV 478 I + ++ R L V A D+G + +A V I ++ + + P + Sbjct: 955 -IRTMRMFSYRDPRHQRLVVVAKDNGDPALSATVTIKLSTVETAVKAYSDMTEVPLEYDI 1013 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA-VAHHDQQFVINPQTGAITTNK 537 F D + V+ + + + I +T + + + A + VI+ + I + Sbjct: 1014 FSDLNL-YLVIGLGSVSFLLLITILVTIVIKCQKPKASKAAPACRNSVISERNSTIADST 1072 Query: 538 LLDR----------ETMSGYLLTVTARDGGVPSLSDTTD-------VEISVVDVNDNEPV 580 L+ ET G L+ G P L T + +E+ + D+NDN P Sbjct: 1073 LVSNDAYWYSLFLAETRKGKLVVRQPVPKGSPRLDATIENPVRMFNIEVEITDINDNAPH 1132 Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640 F++ +I E + VG S A D DVG N Y L + F I+ +G Sbjct: 1133 FRRGTMHLDISESSSVGERFSLNNAADPDVGSNSVKDYHLSASEH----FSINIQTGRDG 1188 Query: 641 TN-------KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693 T KALDRE A H+L A+DGG P ++ T + +++ D+ND+ P F+ + Sbjct: 1189 TKFADLILTKALDREMQAVHNLILTAVDGGVPTRTGTASIVVRVLDVNDNAPSFDREKYV 1248 Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNA--VVHYSIKGGDDSNS-FSLETRQGSDKA-ELV 749 + ENSPIG+ + ++ A D DEG N+ V YS+ + + F L G + E++ Sbjct: 1249 VDVMENSPIGSLVLKLNATDLDEGSNSDIVYSYSLYTSERTQQVFHLNPENGEIRVREMI 1308 Query: 750 TMVDLDYESPRKKYEL-VIRAASPP--LWNDVRVEILVTDVNDNAP--VMKDFQ 798 DL K +E+ VI + P L ++ I VTD+NDN P +K FQ Sbjct: 1309 NYEDL------KLFEMEVIASDKGPNLLSGQCKLTIQVTDMNDNHPEISIKSFQ 1356 Score = 111 bits (268), Expect = 2e-22 Identities = 142/565 (25%), Positives = 224/565 (39%), Gaps = 64/565 (11%) Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM-PGQYEV 373 +G +Y D E + ++ + A D G PP S+ T + P + + Sbjct: 43 NGNLYALKTFDYEIEKEFLFHIEARDSGSPPLSSNVTVHIVIVDQNDNAPVIVSPWRAQG 102 Query: 374 ELAEDEPP-----GTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 + E++ P G+ V + A D D ++R+ Y++ FS+ NG I Sbjct: 103 SVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQLLQVTDATLFSLDQYNGE--IRTM 160 Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN---APYTASVFEDAP 483 + ++ R L V A D+G + +A V I ++ + + P +F D Sbjct: 161 RMFSYRDPRHQRLVVVAKDNGDPALSATVTIKLSTVETAVKAYSDMTEVPLEYDIFSDLN 220 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEA-VAHHDQQFVINPQTGAITTNKLLDRE 542 + V+ + + + I +T + + + A + VI+ + I + L+ + Sbjct: 221 L-YLVIGLGSVSFLLLITILVTIVIKCQKPKASKAAPACRNSVISERNSTIADSTLVSND 279 Query: 543 TMSGYLLTVTARDGG------VPSLS--DTT--------DVEISVVDVNDNEPVFKQQLY 586 L R G VP S D T ++E+ + D+NDN P F++ Sbjct: 280 AYWYSLFLAETRKGKLVVRQPVPKGSRLDATIENPVRMFNIEVEITDINDNAPHFRRGTM 339 Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT----- 641 +I E + VG S A D DVG N Y L + F I+ +G T Sbjct: 340 HLDISESSSVGERFSLNNAADPDVGSNSVKDYHLSASEH----FSINIQTGRDGTKFADL 395 Query: 642 --NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699 KALDRE A H+L A+DGG P ++ D+ND+ P + EN Sbjct: 396 ILTKALDREMQAVHNLILTAVDGGVPTRT----------DMNDNHPEISIKSFQSPVKEN 445 Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK-AELVTMVDLDYES 758 + T I + D D G N VV I D F L RQ SD ELV LD E Sbjct: 446 IDVETVIAVVSVSDKDSGDNGVVDLHI---PDKMPFKL--RQSSDNYYELVVSEPLDREK 500 Query: 759 PRKKYEL---VIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR 815 +Y++ V SPPL ++ + + + DVNDN P ++ P Sbjct: 501 V-PEYDITFTVTDRGSPPLSDNETMTLELLDVNDNVPRFPQSFYTIRVTENNAPGALLSS 559 Query: 816 VPAYDADVTDK--LQYRILSGNNAN 838 + A+D D+ + L Y IL AN Sbjct: 560 LTAFDPDLHENQYLVYFILEKEIAN 584 Score = 87.8 bits (208), Expect = 4e-15 Identities = 64/201 (31%), Positives = 97/201 (48%), Gaps = 12/201 (5%) Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRET 543 GT+V V A D D NA+++Y + + S E + F+ IN +TG I K D ET Sbjct: 2522 GTSVFAVKAFDRDENDNARVSYHILRDGSPE---NKLTSFLNINSETGDILALKSFDFET 2578 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT-------ANIMEDALV 596 + + V A D G PSLS V++ ++D NDN PV + + I + Sbjct: 2579 LKTFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNA 2638 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 G V++V A DAD+G NG + + L + + F +D +G IRT ++ A H L Sbjct: 2639 GHLVTKVRAYDADIGYNGWLLFALQ-EVSDHSLFGLDRYTGQIRTLRSFTETDEAEHKLV 2697 Query: 657 AVAIDGGTPPQSSTVIVHIKI 677 + D G S+T V +K+ Sbjct: 2698 ILVKDNGNVSLSATATVLVKL 2718 Score = 82.6 bits (195), Expect = 1e-13 Identities = 55/191 (28%), Positives = 99/191 (51%), Gaps = 18/191 (9%) Query: 174 IKATDADVGANSAIRYAII-GGNTQMQFS----IDSLSGDVSLVKTLDYEQVRSYRLVIR 228 +KA D D N+ + Y I+ G+ + + + I+S +GD+ +K+ D+E +++++ + Sbjct: 2528 VKAFDRDENDNARVSYHILRDGSPENKLTSFLNINSETGDILALKSFDFETLKTFQFQVV 2587 Query: 229 AQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ-------ESVSENVPIGYSIVRVQA 281 A D GSPS S+ + + I D NDNAP + E + NV G+ + +V+A Sbjct: 2588 ASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHLVTKVRA 2647 Query: 282 YDADEGVNAELTYTMTD-KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD 340 YDAD G N L + + + D++ +D +G + T +A+++L++ D Sbjct: 2648 YDADIGYNGWLLFALQEVSDHS-----LFGLDRYTGQIRTLRSFTETDEAEHKLVILVKD 2702 Query: 341 GGDPPRSATAT 351 G+ SATAT Sbjct: 2703 NGNVSLSATAT 2713 Score = 75.8 bits (178), Expect = 2e-11 Identities = 61/219 (27%), Positives = 100/219 (45%), Gaps = 22/219 (10%) Query: 34 EGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRID 93 E GT+V +KA D+D NA V Y I D +PE+ + I+ Sbjct: 2517 EANQPGTSVFAVKAFDRDENDNARVSYHI---LRDG-SPENK----------LTSFLNIN 2562 Query: 94 GRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN-----YP 148 +G +L S D E + + V A+D SP LSS T+ V I+D NDN YP Sbjct: 2563 SETGDILALKSFDFETLKTFQFQVVASDSGSP---SLSSNVTVKVFILDQNDNAPVILYP 2619 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 S + + +V ++ K++A DAD+G N + +A+ + F +D +G Sbjct: 2620 VSSNGSAEGLEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTGQ 2679 Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 + +++ ++LVI +D G+ S S T +L+ + Sbjct: 2680 IRTLRSFTETDEAEHKLVILVKDNGNVSLSATATVLVKL 2718 Score = 73.7 bits (173), Expect = 7e-11 Identities = 47/155 (30%), Positives = 74/155 (47%), Gaps = 7/155 (4%) Query: 96 SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSE--K 153 +G L + D E + ++A D SP LSS T+H+ I+D NDN P + Sbjct: 43 NGNLYALKTFDYEIEKEFLFHIEARDSGSPP---LSSNVTVHIVIVDQNDNAPVIVSPWR 99 Query: 154 TYTVSVDEDI--SVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSL 211 V+E I S ++AK+ A D D NS I Y ++ FS+D +G++ Sbjct: 100 AQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQLLQVTDATLFSLDQYNGEIRT 159 Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 ++ Y R RLV+ A+D G P+ S T + ++ Sbjct: 160 MRMFSYRDPRHQRLVVVAKDNGDPALSATVTIKLS 194 Score = 67.7 bits (158), Expect = 4e-09 Identities = 47/152 (30%), Positives = 72/152 (47%), Gaps = 10/152 (6%) Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP------RFYT 259 +G++ +KT DYE + + I A+D GSP S+ + I I D NDNAP R Sbjct: 43 NGNLYALKTFDYEIEKEFLFHIEARDSGSPPLSSNVTVHIVIVDQNDNAPVIVSPWRAQG 102 Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319 S+ +E + + G + +V A D D N+ +TY + + L ++D +G + Sbjct: 103 SVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQLLQ---VTDATL-FSLDQYNGEIR 158 Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 T +L+V A D GDP SAT T Sbjct: 159 TMRMFSYRDPRHQRLVVVAKDNGDPALSATVT 190 Score = 64.5 bits (150), Expect = 4e-08 Identities = 48/153 (31%), Positives = 70/153 (45%), Gaps = 7/153 (4%) Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT- 587 + G + K D E +L + ARD G P LS V I +VD NDN PV Sbjct: 42 ENGNLYALKTFDYEIEKEFLFHIEARDSGSPPLSSNVTVHIVIVDQNDNAPVIVSPWRAQ 101 Query: 588 ANIMEDAL-----VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN 642 +++E+ + G+ V++V A D D N RI Y+L + + F +D +G IRT Sbjct: 102 GSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQL-LQVTDATLFSLDQYNGEIRTM 160 Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675 + L VA D G P S+TV + + Sbjct: 161 RMFSYRDPRHQRLVVVAKDNGDPALSATVTIKL 193 Score = 61.7 bits (143), Expect = 3e-07 Identities = 48/157 (30%), Positives = 75/157 (47%), Gaps = 11/157 (7%) Query: 597 GTSVSQVGATDADVGLNGRIHYEL----DPKDREEGSFVIDPASGVIRTNKALDRESVAT 652 GTSV V A D D N R+ Y + P+++ I+ +G I K+ D E++ T Sbjct: 2522 GTSVFAVKAFDRDENDNARVSYHILRDGSPENKLTSFLNINSETGDILALKSFDFETLKT 2581 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF----ESDCLTFYISE---NSPIGTT 705 + VA D G+P SS V V + I D ND+ PV S+ + E N G Sbjct: 2582 FQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNVNAGHL 2641 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 + ++RA+D D G N + ++++ D + F L+ G Sbjct: 2642 VTKVRAYDADIGYNGWLLFALQEVSDHSLFGLDRYTG 2678 Score = 60.5 bits (140), Expect = 7e-07 Identities = 60/211 (28%), Positives = 98/211 (46%), Gaps = 21/211 (9%) Query: 377 EDEPPGTPVVTLTATDADE-DN-RLHYEIT-GGNTRGRFS--ITSQNGRGLITVAQPLDF 431 E PGT V + A D DE DN R+ Y I G+ + + + + G I + DF Sbjct: 2517 EANQPGTSVFAVKAFDRDENDNARVSYHILRDGSPENKLTSFLNINSETGDILALKSFDF 2576 Query: 432 KQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVF---ENAPYTASVFEDAP--- 483 + + + V A+DSG S V++ I D N+ APV ++ +A E+ P Sbjct: 2577 ETLKTFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVILYPVSSNGSAEGLEEIPRNV 2636 Query: 484 -IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 G V V A D+D+G N + ++L E+S+ ++ F ++ TG I T + Sbjct: 2637 NAGHLVTKVRAYDADIGYNGWLLFALQ-EVSDHSL------FGLDRYTGQIRTLRSFTET 2689 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 + + L + +D G SLS T V + +V+ Sbjct: 2690 DEAEHKLVILVKDNGNVSLSATATVLVKLVE 2720 Score = 57.6 bits (133), Expect = 5e-06 Identities = 33/103 (32%), Positives = 58/103 (56%), Gaps = 4/103 (3%) Query: 695 YISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-KGGDDSNSFSLETRQGSDKAELVTMVD 753 YI N P GT++ ++A D DE NA V Y I + G N + S+ +++ + Sbjct: 2515 YIEANQP-GTSVFAVKAFDRDENDNARVSYHILRDGSPENKLTSFLNINSETGDILALKS 2573 Query: 754 LDYESPRK-KYELVIR-AASPPLWNDVRVEILVTDVNDNAPVM 794 D+E+ + ++++V + SP L ++V V++ + D NDNAPV+ Sbjct: 2574 FDFETLKTFQFQVVASDSGSPSLSSNVTVKVFILDQNDNAPVI 2616 Score = 43.2 bits (97), Expect = 0.11 Identities = 28/95 (29%), Positives = 44/95 (46%), Gaps = 2/95 (2%) Query: 258 YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY-TMTDKDYTGNVDLPITIDPRSG 316 Y S + + N P G S+ V+A+D DE NA ++Y + D + + I+ +G Sbjct: 2508 YRSGDKRYIEANQP-GTSVFAVKAFDRDENDNARVSYHILRDGSPENKLTSFLNINSETG 2566 Query: 317 WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 + D ET +Q V A+D G P S+ T Sbjct: 2567 DILALKSFDFETLKTFQFQVVASDSGSPSLSSNVT 2601 Score = 39.1 bits (87), Expect = 1.7 Identities = 41/197 (20%), Positives = 81/197 (41%), Gaps = 11/197 (5%) Query: 737 LETRQGSDKAELVTMVDLDYESPRK-KYELVIR-AASPPLWNDVRVEILVTDVNDNAPVM 794 L + ++ L + DYE ++ + + R + SPPL ++V V I++ D NDNAPV+ Sbjct: 35 LRSFYSAENGNLYALKTFDYEIEKEFLFHIEARDSGSPPLSSNVTVHIVIVDQNDNAPVI 94 Query: 795 -----KDFQIIFNNYKDCFPVGPF-GRVPAYDADV--TDKLQYRILSGNNANLILLNETT 846 ++ G +V A D D ++ Y++L +A L L++ Sbjct: 95 VSPWRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQLLQVTDATLFSLDQYN 154 Query: 847 GSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAE 906 G + + P+ + V D + ++++L T E + + + Sbjct: 155 GEIRTMRMFSYRDPRHQRLVVVAKDN-GDPALSATVTIKLSTVETAVKAYSDMTEVPLEY 213 Query: 907 QFLSPLLGFFIDGLAAI 923 S L + + GL ++ Sbjct: 214 DIFSDLNLYLVIGLGSV 230 >UniRef50_UPI00004F6742 Cluster: protocadherin 1 gamma 32; n=3; Danio rerio|Rep: protocadherin 1 gamma 32 - Danio rerio Length = 961 Score = 229 bits (559), Expect = 1e-57 Identities = 179/609 (29%), Positives = 285/609 (46%), Gaps = 34/609 (5%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F +D SGAL+ + ++DRE + + Q S + + L + + + I+D NDN PQ Sbjct: 92 FNVDLTSGALVIKETMDREILCGGRLHCHIRIQIS-LQNPLEMHS-VSIEIVDVNDNAPQ 149 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD- 208 F + ++ V E + A D DVG NS +R + N ID+ S Sbjct: 150 FQSQNTSLEVSE--AAAPGTSFRLESAHDPDVGVNS-LRAYYLSQNDCFILKIDTKSDGS 206 Query: 209 ----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 + L K LD E++ YRL++ A DGGS +S + + INI DVNDNAP F + Sbjct: 207 KIPILVLNKPLDREKMSEYRLILTAVDGGSAEKSGNSAVFINILDVNDNAPHFLNPTKRV 266 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 ++ EN P G + + A DAD G N E++YT DK +V ++D +G + +G + Sbjct: 267 TLLENSPHGTLVTLLNASDADHGQNGEISYTF-DKYTPDSVLKLFSVDSVTGEIRVTGLI 325 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 D E + + V A D G PP + ++ED GT Sbjct: 326 DHELAKVHDVTVLARDKGMPPMEGSCNIKIEIIDVNDNTPEISINMVSSVISEDVTLGTV 385 Query: 385 VVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP--LDFKQERRYVLT 440 + + D D ++ ++ I G F I+S +GL T+ LD + Y +T Sbjct: 386 IALIKVKDEDTGKNGEVNLHIPYGLP---FKISSPY-KGLFTLMADGLLDREAVAEYTIT 441 Query: 441 VSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498 V+ATDSG RS + ++D N+ P+F Y+ + E+ +L VSA+D DV Sbjct: 442 VTATDSGSPPRSSQKSFVLCLSDVNDNPPIFSQPSYSVDIAENNAPNAPLLSVSASDPDV 501 Query: 499 GINAQITYSLSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETMSGYLLTVTARDGG 557 G N+ I++S+ + +EA+ +V INP +G I + D E ++ + V +D G Sbjct: 502 GENSTISFSI---LESEALGLSVSSYVYINPNSGQIYAIRKFDYEHLNAFQFVVQVQDRG 558 Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN------IMEDALVGTSVSQVGATDADVG 611 PS S V + + D ND+ P+ T++ I A +G V+++ D D G Sbjct: 559 TPSQSSNATVHVFIKDQNDHPPILIYPAPTSDGTLHFFIPRTASIGHLVNRITFVDGDSG 618 Query: 612 LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE-SVATHDLKAVAIDGGTPPQSST 670 N + Y + D E F ID +G +RT + L E S + L + D G P +S++ Sbjct: 619 HNAWLFYSILGPDAE--MFHIDAHTGELRTAQKLSEEDSKSVFSLNVIVKDNGRPSRSAS 676 Query: 671 VIVHIKIED 679 V V+I + + Sbjct: 677 VAVNITLAE 685 Score = 212 bits (517), Expect = 1e-52 Identities = 176/596 (29%), Positives = 269/596 (45%), Gaps = 38/596 (6%) Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLV--IRAQDG-GSPSRSNTTQLLINI 247 II + F++D SG + + +T+D E + RL IR Q +P ++ I I Sbjct: 83 IISESNDKYFNVDLTSGALVIKETMDREILCGGRLHCHIRIQISLQNPLEMHSVS--IEI 140 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD-YTGNVD 306 DVNDNAP+F + VSE G S A+D D GVN+ Y ++ D + +D Sbjct: 141 VDVNDNAPQFQSQNTSLEVSEAAAPGTSFRLESAHDPDVGVNSLRAYYLSQNDCFILKID 200 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 + + + + LDRE ++Y+L++TA DGG +S + F Sbjct: 201 TK-SDGSKIPILVLNKPLDREKMSEYRLILTAVDGGSAEKSGNSAVFINILDVNDNAPHF 259 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHY---EITGGNTRGRFSITSQNGRG 421 + V L E+ P GT V L A+DAD ++ + Y + T + FS+ S G Sbjct: 260 LNPTKRVTLLENSPHGTLVTLLNASDADHGQNGEISYTFDKYTPDSVLKLFSVDSVTGE- 318 Query: 422 LITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVF 479 I V +D + + + +TV A D G + ++I I D N+ P ++ + Sbjct: 319 -IRVTGLIDHELAKVHDVTVLARDKGMPPMEGSCNIKIEIIDVNDNTPEISINMVSSVIS 377 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 ED +GT + ++ D D G N ++ + + + + + F + + LL Sbjct: 378 EDVTLGTVIALIKVKDEDTGKNGEVNLHIPYGLPFKISSPYKGLFTL-------MADGLL 430 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 DRE ++ Y +TVTA D G P S + + DVNDN P+F Q Y+ +I E+ Sbjct: 431 DREAVAEYTITVTATDSGSPPRSSQKSFVLCLSDVNDNPPIFSQPSYSVDIAENNAPNAP 490 Query: 600 VSQVGATDADVGLNGRIHY---ELDPKDREEGSFV-IDPASGVIRTNKALDRESVATHDL 655 + V A+D DVG N I + E + S+V I+P SG I + D E + Sbjct: 491 LLSVSASDPDVGENSTISFSILESEALGLSVSSYVYINPNSGQIYAIRKFDYEHLNAFQF 550 Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF-----ESD-CLTFYISENSPIGTTIGEI 709 D GTP QSS VH+ I+D ND PP+ SD L F+I + IG + I Sbjct: 551 VVQVQDRGTPSQSSNATVHVFIKDQNDHPPILIYPAPTSDGTLHFFIPRTASIGHLVNRI 610 Query: 710 RAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765 D D G NA + YSI G D+ F ++ G EL T L E + + L Sbjct: 611 TFVDGDSGHNAWLFYSIL-GPDAEMFHIDAHTG----ELRTAQKLSEEDSKSVFSL 661 Score = 196 bits (479), Expect = 5e-48 Identities = 162/592 (27%), Positives = 266/592 (44%), Gaps = 58/592 (9%) Query: 4 PFCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 P +H I ++D ND++P F+ Q V E A+ GT+ A D D+G N+ Sbjct: 130 PLEMHSVSIEIVDVNDNAPQFQSQNTSLEVSEAAAPGTSFRLESAHDPDVGVNS------ 183 Query: 63 ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122 + A L+ D D + L+ LDREK++ Y +++ A D Sbjct: 184 --LRAYYLSQNDCFILKI-------DTKSDGSKIPILVLNKPLDREKMSEYRLILTAVDG 234 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 S S + + +NI+D NDN P F T V++ E + ++ + A+DAD G Sbjct: 235 GSA---EKSGNSAVFINILDVNDNAPHFLNPTKRVTLLE--NSPHGTLVTLLNASDADHG 289 Query: 183 ANSAIRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239 N I Y + FS+DS++G++ + +D+E + + + + A+D G P Sbjct: 290 QNGEISYTFDKYTPDSVLKLFSVDSVTGEIRVTGLIDHELAKVHDVTVLARDKGMPPMEG 349 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 + + I I DVNDN P ++ +SE+V +G I ++ D D G N E+ + Sbjct: 350 SCNIKIEIIDVNDNTPEISINMVSSVISEDVTLGTVIALIKVKDEDTGKNGEVNLHIP-- 407 Query: 300 DYTGNVDLPITI-DPRSG--WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 LP I P G + G LDRE A+Y + VTATD G PPRS+ + Sbjct: 408 -----YGLPFKISSPYKGLFTLMADGLLDREAVAEYTITVTATDSGSPPRSSQKSFVLCL 462 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSI 414 F Y V++AE+ P P+++++A+D D E++ + + I G S+ Sbjct: 463 SDVNDNPPIFSQPSYSVDIAENNAPNAPLLSVSASDPDVGENSTISFSILESEALG-LSV 521 Query: 415 TS----QNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPV 468 +S G I + D++ + V D G +S A V + I D N++ P+ Sbjct: 522 SSYVYINPNSGQIYAIRKFDYEHLNAFQFVVQVQDRGTPSQSSNATVHVFIKDQNDHPPI 581 Query: 469 FENAPYTAS------VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522 T+ + A IG V ++ D D G NA + YS+ + +A + Sbjct: 582 LIYPAPTSDGTLHFFIPRTASIGHLVNRITFVDGDSGHNAWLFYSI---LGPDA-----E 633 Query: 523 QFVINPQTGAI-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 F I+ TG + T KL + ++ S + L V +D G PS S + V I++ + Sbjct: 634 MFHIDAHTGELRTAQKLSEEDSKSVFSLNVIVKDNGRPSRSASVAVNITLAE 685 Score = 180 bits (437), Expect = 7e-43 Identities = 122/441 (27%), Positives = 215/441 (48%), Gaps = 20/441 (4%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSI-TSQNGRGL- 422 F +E++E PGT +A D D N L N I T +G + Sbjct: 150 FQSQNTSLEVSEAAAPGTSFRLESAHDPDVGVNSLRAYYLSQNDCFILKIDTKSDGSKIP 209 Query: 423 -ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVF 479 + + +PLD ++ Y L ++A D G +S + V INI D N+ AP F N ++ Sbjct: 210 ILVLNKPLDREKMSEYRLILTAVDGGSAEKSGNSAVFINILDVNDNAPHFLNPTKRVTLL 269 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E++P GT V +++A+D+D G N +I+Y+ + + + F ++ TG I L+ Sbjct: 270 ENSPHGTLVTLLNASDADHGQNGEISYTFDKYTPDSVL----KLFSVDSVTGEIRVTGLI 325 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 D E + +TV ARD G+P + + +++I ++DVNDN P + ++ I ED +GT Sbjct: 326 DHELAKVHDVTVLARDKGMPPMEGSCNIKIEIIDVNDNTPEISINMVSSVISEDVTLGTV 385 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV--IRTNKALDRESVATHDLKA 657 ++ + D D G NG ++ + P + P G+ + + LDRE+VA + + Sbjct: 386 IALIKVKDEDTGKNGEVNLHI-PYGLPFK--ISSPYKGLFTLMADGLLDREAVAEYTITV 442 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A D G+PP+SS + + D+ND+PP+F + I+EN+ + + A DPD G Sbjct: 443 TATDSGSPPRSSQKSFVLCLSDVNDNPPIFSQPSYSVDIAENNAPNAPLLSVSASDPDVG 502 Query: 718 PNAVVHYSIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPP 773 N+ + +SI + S S + ++ + DYE ++ V++ +P Sbjct: 503 ENSTISFSILESEALGLSVSSYVYINPNSGQIYAIRKFDYEH-LNAFQFVVQVQDRGTPS 561 Query: 774 LWNDVRVEILVTDVNDNAPVM 794 ++ V + + D ND+ P++ Sbjct: 562 QSSNATVHVFIKDQNDHPPIL 582 Score = 167 bits (406), Expect = 4e-39 Identities = 123/376 (32%), Positives = 177/376 (47%), Gaps = 17/376 (4%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 V I I D N+ AP F++ + V E A GT+ + SA D DVG+N+ Y LS N Sbjct: 136 VSIEIVDVNDNAPQFQSQNTSLEVSEAAAPGTSFRLESAHDPDVGVNSLRAYYLSQ---N 192 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 + + + NK LDRE MS Y L +TA DGG S + V I+++DV Sbjct: 193 DCFILKIDTKSDGSKIPILVLNKPLDREKMSEYRLILTAVDGGSAEKSGNSAVFINILDV 252 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP--KDREEGSFVI 632 NDN P F ++E++ GT V+ + A+DAD G NG I Y D D F + Sbjct: 253 NDNAPHFLNPTKRVTLLENSPHGTLVTLLNASDADHGQNGEISYTFDKYTPDSVLKLFSV 312 Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692 D +G IR +D E HD+ +A D G PP + + I+I D+ND+ P + + Sbjct: 313 DSVTGEIRVTGLIDHELAKVHDVTVLARDKGMPPMEGSCNIKIEIIDVNDNTPEISINMV 372 Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752 + ISE+ +GT I I+ D D G N V+ I G F + + K M Sbjct: 373 SSVISEDVTLGTVIALIKVKDEDTGKNGEVNLHIPYG---LPFKISSPY---KGLFTLMA 426 Query: 753 D--LDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC 807 D LD E+ +Y + + A SPP + + ++DVNDN P+ + ++ Sbjct: 427 DGLLDREAV-AEYTITVTATDSGSPPRSSQKSFVLCLSDVNDNPPIFSQPSYSVDIAENN 485 Query: 808 FPVGPFGRVPAYDADV 823 P P V A D DV Sbjct: 486 APNAPLLSVSASDPDV 501 Score = 157 bits (382), Expect = 3e-36 Identities = 135/471 (28%), Positives = 205/471 (43%), Gaps = 40/471 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 IN+LD ND++P F ++ E + GT V L A+D D G+N E+ YT + T D+ Sbjct: 247 INILDVNDNAPHFLNPTKRVTLLENSPHGTLVTLLNASDADHGQNGEISYTFDKYTPDS- 305 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 V +F +D +G + +D E + V V A D+ P + Sbjct: 306 ---------------VLKLFSVDSVTGEIRVTGLIDHELAKVHDVTVLARDKGMP---PM 347 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + I + IID NDN P+ S + + ED VT VIA IK D D G N + Sbjct: 348 EGSCNIKIEIIDVNDNTPEISINMVSSVISED--VTLGTVIALIKVKDEDTGKNGEVNLH 405 Query: 191 IIGGNTQMQFSIDS-LSGDVSLVK--TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 I G + F I S G +L+ LD E V Y + + A D GSP RS+ ++ + Sbjct: 406 IPYG---LPFKISSPYKGLFTLMADGLLDREAVAEYTITVTATDSGSPPRSSQKSFVLCL 462 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NVD 306 DVNDN P F + ++EN ++ V A D D G N+ +++++ + + G +V Sbjct: 463 SDVNDNPPIFSQPSYSVDIAENNAPNAPLLSVSASDPDVGENSTISFSILESEALGLSVS 522 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 + I+P SG +Y + D E +Q +V D G P +S+ AT Sbjct: 523 SYVYINPNSGQIYAIRKFDYEHLNAFQFVVQVQDRGTPSQSSNATVHVFIKDQNDHPPIL 582 Query: 367 M------PGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQN 418 + G + G V +T D D + L Y I G + F I + Sbjct: 583 IYPAPTSDGTLHFFIPRTASIGHLVNRITFVDGDSGHNAWLFYSILGPDAE-MFHIDAHT 641 Query: 419 GRGLITVAQPLDFKQERR-YVLTVSATDSGGRSDTAMVQINITDANNYAPV 468 G + AQ L + + + L V D+G S +A V +NIT A + V Sbjct: 642 GE--LRTAQKLSEEDSKSVFSLNVIVKDNGRPSRSASVAVNITLAEKSSDV 690 >UniRef50_Q8IGX4 Cluster: RE10062p; n=6; Diptera|Rep: RE10062p - Drosophila melanogaster (Fruit fly) Length = 1820 Score = 229 bits (559), Expect = 1e-57 Identities = 224/806 (27%), Positives = 351/806 (43%), Gaps = 81/806 (10%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 VF +D +G + R LDRE V++ TD+ ++ + + + + NDN P Sbjct: 67 VFSVDRETGVVRLRQELDRETQDTVEVIISITDEGIYGTEPNTVSQRRVIPVRYYNDNQP 126 Query: 149 QFSEKTYTVSVDEDISV-TDNPVIAKIKATDADVGANSAIRYAIIGGNT--------QMQ 199 F + YT SV E + V ++ V I D D G NS ++ + N ++ Sbjct: 127 TFLGRPYTASVSESLPVGSELSVEPPIVVVDRDEGINSEVQMKCLEENDICDIFEVRAVK 186 Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR-SNTTQLLINIRDVNDNAPRFY 258 S + + V+L + LD+E SY L I A D +R S+ + IN+ D+ D P F Sbjct: 187 ISDGNYTARVALKQQLDFESRPSYILTISASDSALDNRLSSLATISINVIDIQDQPPIFT 246 Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV 318 + + +V EN P G SI+ V+A D D G+ E+ ++ D+ + G+ +L DPR G Sbjct: 247 NAPYSATVPENTPAGVSILTVKAVDGDVGIPREIFLSLEDEPF-GHFELVPFGDPRDGTA 305 Query: 319 Y---TSGQLDRETQ------AKYQLLVTAT---DGGDPPRSATATXXXXXXXXXXXXXXF 366 TS LDRE Y + AT DG P + F Sbjct: 306 VLQTTSEPLDRENAEILQNGGVYVFSIRATELIDGAIPAEHSLTRVTIVVTDVDDHQPTF 365 Query: 367 MPGQYEVELAEDEPPGTPV--VTLTATDADEDNRLHYEITGG---NTRGRFSI--TSQNG 419 + V + E+ G P+ +++ D D YE++ N F + T G Sbjct: 366 SGPHFNVSITENLANGMPLPGLSIFVDDRDMGENSRYELSLRDVFNAARVFEVSPTESQG 425 Query: 420 RGLITV----AQPLDFK----QERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN 471 R + V A LD+ R++ + A+ G V+I++ DAN+ APVF+ Sbjct: 426 RTPVVVKVLNASRLDYDVVDPDLRKFEFDLVASVKGVEKAKTRVEIHLLDANDNAPVFDQ 485 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 Y + E+ P+ + V ATD D G + Y L ++ F +NP+TG Sbjct: 486 GTYRFTAAENLPVDAIIGHVKATDLDSGEFGHVRYVLKGFGADN--------FYVNPETG 537 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 + K LD E S Y LTV A DGG + ++ + V DVNDN P F+ + Y+ I Sbjct: 538 GVYLLKPLDYEKQSSYSLTVVAIDGGQREAN--ANLFVGVTDVNDNHPNFESKEYSRTIR 595 Query: 592 EDALVGTSVSQVGATDADVGL--NGRIHYELDPKDREEGS-FVIDPASGVIRTNKA---L 645 E A + V A DAD NGR+ Y + ++ G+ F I+P +G I KA + Sbjct: 596 EGAALFEPQFFVRAHDADGPSQGNGRVKYSIVSENSIAGNVFRIEPDTGEIVIQKAARSM 655 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY---------- 695 D E ++L A D G PP S+T V +++ + P+F Sbjct: 656 DTER-GEYELVVSATDFGIPPLSNTTRVLVRVGISGNQRPIFRGHFQNMENLPIIGPPSY 714 Query: 696 ---ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752 I EN+ G+ + + AHDPD G ++++ Y I G +D+ F ++ G + Sbjct: 715 RVSIPENAAAGSNVTSVSAHDPD-GLDSLLRYRIVGANDN--FEIDEISGLITVSPQARI 771 Query: 753 DLDYESPRKKYELVIRAASP----PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY-KDC 807 D D S +E+++ A P V + V D+ND P + Q + Y + Sbjct: 772 DRD--SNMNSFEIIVNAVDSGTPIPETATTTVYVNVKDINDERPKFE--QNSYATYVSER 827 Query: 808 FPVGPFG-RVPAYDADVTDKLQYRIL 832 VG RV A D D+ KL+Y ++ Sbjct: 828 TAVGESVLRVKAIDKDLNSKLEYSMV 853 Score = 219 bits (536), Expect = 7e-55 Identities = 242/920 (26%), Positives = 405/920 (44%), Gaps = 114/920 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGK--NAEVEYTIELVTAD 68 + V D ND+ P FE ++Y ++REGA+ ++A D D N V+Y+I V+ + Sbjct: 573 VGVTDVNDNHPNFESKEYSRTIREGAALFEPQFFVRAHDADGPSQGNGRVKYSI--VSEN 630 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRA---SLDREKVARYTVLVKATDQASP 125 ++ +VFRI+ +G ++ + S+D E+ Y ++V ATD P Sbjct: 631 SI---------------AGNVFRIEPDTGEIVIQKAARSMDTER-GEYELVVSATDFGIP 674 Query: 126 VSDRLSSTATIHVNI-IDDN------------DNYPQFSEKTYTVSVDEDISVTDNPVIA 172 LS+T + V + I N +N P +Y VS+ E+ + N + Sbjct: 675 P---LSNTTRVLVRVGISGNQRPIFRGHFQNMENLPIIGPPSYRVSIPENAAAGSN--VT 729 Query: 173 KIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG--DVSLVKTLDYEQ-VRSYRLVIRA 229 + A D D G +S +RY I+G N F ID +SG VS +D + + S+ +++ A Sbjct: 730 SVSAHDPD-GLDSLLRYRIVGANDN--FEIDEISGLITVSPQARIDRDSNMNSFEIIVNA 786 Query: 230 QDGGSP-SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV 288 D G+P + TT + +N++D+ND P+F + + VSE +G S++RV+A D D + Sbjct: 787 VDSGTPIPETATTTVYVNVKDINDERPKFEQNSYATYVSERTAVGESVLRVKAIDKD--L 844 Query: 289 NAELTYTMTDK-DYTGNVDLPIT------------IDPRSGWVYTSGQLDRETQAKYQLL 335 N++L Y+M T + I +D +SG ++ +G L + A Sbjct: 845 NSKLEYSMVGPVAATTKAGVSIANRSNYRLQEAFRVDSQSGEIFVNGTLRHDVAAIIIFT 904 Query: 336 VTATDGG---DPPRSATATXXXXXXXXXXXXXXFMPGQ--------YEVELAEDEPPGTP 384 V D DP T +V++ E+ P + Sbjct: 905 VGVRDLNAEVDPEGQVDTTEVTVYVQSFQDTNPVFKNTGWTSSRPVIDVKIKEEMPIDSA 964 Query: 385 VVTLTATDADEDNRL-HYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ----ERRYVL 439 + L A D + +E+ F + + G + + + LD++ + L Sbjct: 965 LFILQAEDPVTRQPITSFELIEPKQVDYFQVAERTGE--VILKKRLDYEALGDTGPEFEL 1022 Query: 440 TVSATDSGG-RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498 V A + RS + V I + + N+ +P FE Y A++ E+ P V+ V A D D Sbjct: 1023 QVRANSADRQRSTVSRVNITVENVNDNSPRFERNSYQATIIENRPHPERVIRVRALDKDA 1082 Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI--TTNKLLDRETMSGYLLTVTARDG 556 +NA+ +I H F IN TG I + + +DRE L + A D Sbjct: 1083 VLNARDERLGYHKIIYSLQGEHAMLFDINNTTGEIIVASGQTIDRERTPRIQLQIKAEDS 1142 Query: 557 -GVPS--LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613 G P+ +++I V+DVNDN P F Q+ Y+ I E+A + + V Q+ A DAD GL Sbjct: 1143 PGRPTDAKQSVVELQIEVLDVNDNAPEFTQKKYSTVIPENAQIDSFVLQLEAVDADEGLG 1202 Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA-THDLKAVAIDGGT-----PPQ 667 G + YEL + G F ID SG+I T + L + A + L A D G P Sbjct: 1203 GEVRYELVNEGEANGLFKIDTKSGLISTRRNLTGKGRAHPYVLIVRAQDNGNQMPKQPTL 1262 Query: 668 SSTVIVHIKIEDI--NDSPPVFESDCL--TFYISENSPIGTTIGEIRAHDPDE--GPNAV 721 S+ V I I D+ ND P F S + ++EN+ G + ++ A DPD+ P+ Sbjct: 1263 STDTDVRIYIGDVSANDGVPYFLSPRVGQMANVTENAVTGAPVFQVIASDPDDESTPSGT 1322 Query: 722 VHYSI-KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA--SPPLWNDV 778 + Y I D+ +F ++ G + T +D E+ + Y +++ + P + Sbjct: 1323 ITYRILPDTPDAEAFVIDAHSGL----ITTRQSMDRET-KDMYRILLEVSDNGQPKQSAT 1377 Query: 779 RV-EILVTDVNDNAPVM---KDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDK--LQYRI 831 R+ +I + DV+D+ P + + ++ P G G A D D+ + + Y I Sbjct: 1378 RILQIAILDVDDHEPRFAREAGAGPLSMSVREEEPAGTIVGNFSALDEDLGENAAIDYVI 1437 Query: 832 LSGNNANLILLNETTGSMTL 851 + GNN L + S+ + Sbjct: 1438 IDGNNEQLFTIERNNESLAI 1457 Score = 217 bits (530), Expect = 4e-54 Identities = 210/761 (27%), Positives = 338/761 (44%), Gaps = 67/761 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NV D ND P FE Y V E + G +VL +KA D+D+ N+++EY++ A T Sbjct: 803 VNVKDINDERPKFEQNSYATYVSERTAVGESVLRVKAIDKDL--NSKLEYSMVGPVAAT- 859 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS-DR 129 + +Q+ FR+D +SG + +L + A V D + V + Sbjct: 860 -TKAGVSIANRSNYRLQEAFRVDSQSGEIFVNGTLRHDVAAIIIFTVGVRDLNAEVDPEG 918 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE-DISVTDN-PVIAKIKATDAD--VGANS 185 T + V + D P F +T S D+ + + P+ + + A+ V Sbjct: 919 QVDTTEVTVYVQSFQDTNPVFKNTGWTSSRPVIDVKIKEEMPIDSALFILQAEDPVTRQP 978 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV----RSYRLVIRAQDGGSPSRSNTT 241 + +I F + +G+V L K LDYE + + L +RA + RS + Sbjct: 979 ITSFELIEPKQVDYFQVAERTGEVILKKRLDYEALGDTGPEFELQVRA-NSADRQRSTVS 1037 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA---ELTYTMTD 298 ++ I + +VNDN+PRF + +Q ++ EN P ++RV+A D D +NA L Y Sbjct: 1038 RVNITVENVNDNSPRFERNSYQATIIENRPHPERVIRVRALDKDAVLNARDERLGYHKII 1097 Query: 299 KDYTGNVDLPITIDPRSG-WVYTSGQ-LDRETQAKYQLLVTATDGGDPP---RSATATXX 353 G + I+ +G + SGQ +DRE + QL + A D P + + Sbjct: 1098 YSLQGEHAMLFDINNTTGEIIVASGQTIDRERTPRIQLQIKAEDSPGRPTDAKQSVVELQ 1157 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITG-GNTRG 410 F +Y + E+ + V+ L A DADE + YE+ G G Sbjct: 1158 IEVLDVNDNAPEFTQKKYSTVIPENAQIDSFVLQLEAVDADEGLGGEVRYELVNEGEANG 1217 Query: 411 RFSITSQNGRGLITVAQPLDFK-QERRYVLTVSATDSGGR--------SDT-AMVQINIT 460 F I +++ GLI+ + L K + YVL V A D+G + +DT + I Sbjct: 1218 LFKIDTKS--GLISTRRNLTGKGRAHPYVLIVRAQDNGNQMPKQPTLSTDTDVRIYIGDV 1275 Query: 461 DANNYAPVF--ENAPYTASVFEDAPIGTTVLVVSATDSD--VGINAQITYSLSSEISNEA 516 AN+ P F A+V E+A G V V A+D D + ITY + + + Sbjct: 1276 SANDGVPYFLSPRVGQMANVTENAVTGAPVFQVIASDPDDESTPSGTITYRILPDTPDA- 1334 Query: 517 VAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVND 576 + FVI+ +G ITT + +DRET Y + + D G P S T ++I+++DV+D Sbjct: 1335 -----EAFVIDAHSGLITTRQSMDRETKDMYRILLEVSDNGQPKQSATRILQIAILDVDD 1389 Query: 577 NEPVFKQQL----YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632 +EP F ++ + ++ E+ GT V A D D+G N I Y + + E+ F I Sbjct: 1390 HEPRFAREAGAGPLSMSVREEEPAGTIVGNFSALDEDLGENAAIDYVIIDGNNEQ-LFTI 1448 Query: 633 D---PASGVIRTNKALDRESVATHDLKAVAIDGGTP-------PQSSTVIVHIKIE---- 678 + + +++T K +DRE V + L + G P P + H++I Sbjct: 1449 ERNNESLAILKTKKPIDREQVESFTLTIKCLKLGEPGYKFIGDPYDRQDLSHLRINVRVL 1508 Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-EGP 718 DI+D+ P FE T I N PI T + ++A D D E P Sbjct: 1509 DIDDNLPKFEQPDPTVGIRINVPIDTVVTTLKASDADAEAP 1549 Score = 200 bits (488), Expect = 4e-49 Identities = 210/763 (27%), Positives = 337/763 (44%), Gaps = 81/763 (10%) Query: 17 NDHSPVFEMQQYEASVREGASSGTTVLT---LKATDQDIGKNAEVEYTIELVTADTLNPE 73 ND+ P F + Y ASV E G+ + + D+D G N+EV+ L Sbjct: 122 NDNQPTFLGRPYTASVSESLPVGSELSVEPPIVVVDRDEGINSEVQMKC-------LEEN 174 Query: 74 DAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSST 133 D + D + + + LD E Y + + A+D A + +RLSS Sbjct: 175 DICDIFEVRAVKISD----GNYTARVALKQQLDFESRPSYILTISASDSA--LDNRLSSL 228 Query: 134 ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG 193 ATI +N+ID D P F+ Y+ +V E+ + I +KA D DVG I ++ Sbjct: 229 ATISINVIDIQDQPPIFTNAPYSATVPENTPAGVS--ILTVKAVDGDVGIPREIFLSLED 286 Query: 194 ---GNTQMQFSIDSLSGDVSLVKT---LDYEQVRS------YRLVIRAQ---DGGSPSRS 238 G+ ++ D G L T LD E Y IRA DG P+ Sbjct: 287 EPFGHFELVPFGDPRDGTAVLQTTSEPLDRENAEILQNGGVYVFSIRATELIDGAIPAEH 346 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY--DADEGVNAELTYTM 296 + T++ I + DV+D+ P F F S++EN+ G + + + D D G N+ ++ Sbjct: 347 SLTRVTIVVTDVDDHQPTFSGPHFNVSITENLANGMPLPGLSIFVDDRDMGENSRYELSL 406 Query: 297 TDKDYTGNVD--LPITIDPRSGWVY---TSGQLDRETQ----AKYQLLVTATDGGDPPRS 347 D V P R+ V + +LD + K++ + A+ G Sbjct: 407 RDVFNAARVFEVSPTESQGRTPVVVKVLNASRLDYDVVDPDLRKFEFDLVASVKG--VEK 464 Query: 348 ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYE-ITGG 406 A F G Y AE+ P + + ATD D H + G Sbjct: 465 AKTRVEIHLLDANDNAPVFDQGTYRFTAAENLPVDAIIGHVKATDLDSGEFGHVRYVLKG 524 Query: 407 NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYA 466 F + + G + + +PLD++++ Y LTV A D G R A + + +TD N+ Sbjct: 525 FGADNFYVNPETGG--VYLLKPLDYEKQSSYSLTVVAIDGGQREANANLFVGVTDVNDNH 582 Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI--NAQITYSLSSEISNEAVAHHDQQF 524 P FE+ Y+ ++ E A + V A D+D N ++ YS+ SE S +A + F Sbjct: 583 PNFESKEYSRTIREGAALFEPQFFVRAHDADGPSQGNGRVKYSIVSENS---IAGN--VF 637 Query: 525 VINPQTGAITTNKLL-DRETMSG-YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582 I P TG I K +T G Y L V+A D G+P LS+TT V + V + P+F+ Sbjct: 638 RIEPDTGEIVIQKAARSMDTERGEYELVVSATDFGIPPLSNTTRVLVRVGISGNQRPIFR 697 Query: 583 QQL-------------YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629 Y +I E+A G++V+ V A D D GL+ + Y + + + Sbjct: 698 GHFQNMENLPIIGPPSYRVSIPENAAAGSNVTSVSAHDPD-GLDSLLRYRIVGAN---DN 753 Query: 630 FVIDPASGVIRTNKA--LDRES-VATHDLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPP 685 F ID SG+I + +DR+S + + ++ A+D GTP P+++T V++ ++DIND P Sbjct: 754 FEIDEISGLITVSPQARIDRDSNMNSFEIIVNAVDSGTPIPETATTTVYVNVKDINDERP 813 Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 FE + Y+SE + +G ++ ++A D D N+ + YS+ G Sbjct: 814 KFEQNSYATYVSERTAVGESVLRVKAIDKD--LNSKLEYSMVG 854 Score = 196 bits (477), Expect = 1e-47 Identities = 235/944 (24%), Positives = 402/944 (42%), Gaps = 127/944 (13%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I++LD ND++PVF+ Y + E + +KATD D G+ V Y ++ AD Sbjct: 470 EIHLLDANDNAPVFDQGTYRFTAAENLPVDAIIGHVKATDLDSGEFGHVRYVLKGFGADN 529 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 F ++ +G + LD EK + Y++ V A D + Sbjct: 530 --------------------FYVNPETGGVYLLKPLDYEKQSSYSLTVVAID-----GGQ 564 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + A + V + D NDN+P F K Y+ ++ E ++ + + D N ++Y Sbjct: 565 REANANLFVGVTDVNDNHPNFESKEYSRTIREGAALFEPQFFVRAHDADGPSQGNGRVKY 624 Query: 190 AIIGGNT--QMQFSIDSLSGDVSLVK---TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 +I+ N+ F I+ +G++ + K ++D E+ Y LV+ A D G P SNTT++L Sbjct: 625 SIVSENSIAGNVFRIEPDTGEIVIQKAARSMDTER-GEYELVVSATDFGIPPLSNTTRVL 683 Query: 245 I------NIRDV-------NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE 291 + N R + +N P ++ S+ EN G ++ V A+D D G+++ Sbjct: 684 VRVGISGNQRPIFRGHFQNMENLPIIGPPSYRVSIPENAAAGSNVTSVSAHDPD-GLDSL 742 Query: 292 LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ--LDRETQA-KYQLLVTATDGGDP-PRS 347 L Y + + N + ID SG + S Q +DR++ ++++V A D G P P + Sbjct: 743 LRYRIVGAN--DNFE----IDEISGLITVSPQARIDRDSNMNSFEIIVNAVDSGTPIPET 796 Query: 348 ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITG-- 405 AT T F Y ++E G V+ + A D D +++L Y + G Sbjct: 797 ATTTVYVNVKDINDERPKFEQNSYATYVSERTAVGESVLRVKAIDKDLNSKLEYSMVGPV 856 Query: 406 -GNTRGRFSITSQNG------------RGLITVAQPLDFKQERRYVLTV------SATDS 446 T+ SI +++ G I V L + TV + D Sbjct: 857 AATTKAGVSIANRSNYRLQEAFRVDSQSGEIFVNGTLRHDVAAIIIFTVGVRDLNAEVDP 916 Query: 447 GGRSDTAMVQINITDANNYAPVFENAPYTAS-------VFEDAPIGTTVLVVSATDSDVG 499 G+ DT V + + + PVF+N +T+S + E+ PI + + ++ A D Sbjct: 917 EGQVDTTEVTVYVQSFQDTNPVFKNTGWTSSRPVIDVKIKEEMPIDSALFILQAEDP--- 973 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM--SGYLLTVTARDGG 557 + Q S I + V + F + +TG + K LD E + +G + R Sbjct: 974 VTRQPITSFEL-IEPKQVDY----FQVAERTGEVILKKRLDYEALGDTGPEFELQVRANS 1028 Query: 558 VPSLSDTTD-VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR- 615 T V I+V +VNDN P F++ Y A I+E+ V +V A D D LN R Sbjct: 1029 ADRQRSTVSRVNITVENVNDNSPRFERNSYQATIIENRPHPERVIRVRALDKDAVLNARD 1088 Query: 616 ----IHYELDPKDREEGS-FVIDPASG--VIRTNKALDRESVATHDLKAVAIDG-GTPPQ 667 H + E F I+ +G ++ + + +DRE L+ A D G P Sbjct: 1089 ERLGYHKIIYSLQGEHAMLFDINNTTGEIIVASGQTIDRERTPRIQLQIKAEDSPGRPTD 1148 Query: 668 SSTVIVHIKIE--DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 + +V ++IE D+ND+ P F + I EN+ I + + ++ A D DEG V Y Sbjct: 1149 AKQSVVELQIEVLDVNDNAPEFTQKKYSTVIPENAQIDSFVLQLEAVDADEGLGGEVRYE 1208 Query: 726 -IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA--------ASPPLWN 776 + G+ + F ++T+ G + T +L + Y L++RA P L Sbjct: 1209 LVNEGEANGLFKIDTKSGL----ISTRRNLTGKGRAHPYVLIVRAQDNGNQMPKQPTLST 1264 Query: 777 DVRVEILVTDV--NDNAPVMKDFQI--IFNNYKDCFPVGPFGRVPAYDAD----VTDKLQ 828 D V I + DV ND P ++ + N ++ P +V A D D + + Sbjct: 1265 DTDVRIYIGDVSANDGVPYFLSPRVGQMANVTENAVTGAPVFQVIASDPDDESTPSGTIT 1324 Query: 829 YRILSGN-NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 YRIL +A +++ +G +T ++ + + + V+D Sbjct: 1325 YRILPDTPDAEAFVIDAHSGLITTRQSMDRETKDMYRILLEVSD 1368 Score = 182 bits (443), Expect = 1e-43 Identities = 219/851 (25%), Positives = 348/851 (40%), Gaps = 101/851 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 INV+D D P+F Y A+V E +G ++LT+KA D D+G E+ ++E Sbjct: 233 INVIDIQDQPPIFTNAPYSATVPENTPAGVSILTVKAVDGDVGIPREIFLSLE------- 285 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLD-REKVARYTVLVKATDQASPVSDR 129 E +D + + L R + + + Y ++AT+ Sbjct: 286 -DEPFGHFELVPFGDPRDGTAVLQTTSEPLDRENAEILQNGGVYVFSIRATELIDGAIPA 344 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S + + + D +D+ P FS + VS+ E+++ I D D+G NS Sbjct: 345 EHSLTRVTIVVTDVDDHQPTFSGPHFNVSITENLANGMPLPGLSIFVDDRDMGENSRYEL 404 Query: 190 A---IIGGNTQMQFSIDSLSGDVSLV------KTLDYEQV----RSYRLVIRAQDGGSPS 236 + + + S G +V LDY+ V R + + A G Sbjct: 405 SLRDVFNAARVFEVSPTESQGRTPVVVKVLNASRLDYDVVDPDLRKFEFDLVASVKGVEK 464 Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 T++ I++ D NDNAP F ++ + +EN+P+ I V+A D D G + Y + Sbjct: 465 AK--TRVEIHLLDANDNAPVFDQGTYRFTAAENLPVDAIIGHVKATDLDSGEFGHVRYVL 522 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 K + + ++P +G VY LD E Q+ Y L V A DGG R A A Sbjct: 523 --KGFGAD---NFYVNPETGGVYLLKPLDYEKQSSYSLTVVAIDGGQ--REANANLFVGV 575 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD----EDNRLHYEITGGNT-RGR 411 F +Y + E P + A DAD + R+ Y I N+ G Sbjct: 576 TDVNDNHPNFESKEYSRTIREGAALFEPQFFVRAHDADGPSQGNGRVKYSIVSENSIAGN 635 Query: 412 -FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPV 468 F I G +I A + Y L VSATD G S+T V + + + N P+ Sbjct: 636 VFRIEPDTGEIVIQKAARSMDTERGEYELVVSATDFGIPPLSNTTRVLVRVGISGNQRPI 695 Query: 469 F-------ENAP------YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515 F EN P Y S+ E+A G+ V VSA D D G+++ + Y + N Sbjct: 696 FRGHFQNMENLPIIGPPSYRVSIPENAAAGSNVTSVSAHDPD-GLDSLLRYRIVGANDNF 754 Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRET-MSGYLLTVTARDGGVP-SLSDTTDVEISVVD 573 + ++PQ +DR++ M+ + + V A D G P + TT V ++V D Sbjct: 755 EIDEISGLITVSPQA-------RIDRDSNMNSFEIIVNAVDSGTPIPETATTTVYVNVKD 807 Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL------------- 620 +ND P F+Q Y + E VG SV +V A D D LN ++ Y + Sbjct: 808 INDERPKFEQNSYATYVSERTAVGESVLRVKAIDKD--LNSKLEYSMVGPVAATTKAGVS 865 Query: 621 ---DPKDREEGSFVIDPASGVIRTNKALDRESVA----THDLKAVAIDGGTPPQSSTVIV 673 R + +F +D SG I N L + A T ++ + + Q T V Sbjct: 866 IANRSNYRLQEAFRVDSQSGEIFVNGTLRHDVAAIIIFTVGVRDLNAEVDPEGQVDTTEV 925 Query: 674 HIKIEDINDSPPVFES-------DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 + ++ D+ PVF++ + I E PI + + ++A DP + + + Sbjct: 926 TVYVQSFQDTNPVFKNTGWTSSRPVIDVKIKEEMPIDSALFILQAEDP-VTRQPITSFEL 984 Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYES---PRKKYELVIRAASPPLWNDV--RVE 781 + F + R G E++ LDYE+ ++EL +RA S RV Sbjct: 985 IEPKQVDYFQVAERTG----EVILKKRLDYEALGDTGPEFELQVRANSADRQRSTVSRVN 1040 Query: 782 ILVTDVNDNAP 792 I V +VNDN+P Sbjct: 1041 ITVENVNDNSP 1051 Score = 169 bits (411), Expect = 1e-39 Identities = 182/675 (26%), Positives = 294/675 (43%), Gaps = 76/675 (11%) Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 S+SEN P+G + +++ D + G L Y+++ G V ++D +G V +L Sbjct: 35 SLSENTPVGSPVFQLKGTDPEGG---RLKYSIS-----GPV---FSVDRETGVVRLRQEL 83 Query: 325 DRETQAKYQLLVTATDGG---DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381 DRETQ +++++ TD G P + + F+ Y ++E P Sbjct: 84 DRETQDTVEVIISITDEGIYGTEPNTVSQRRVIPVRYYNDNQPTFLGRPYTASVSESLPV 143 Query: 382 GTPVVT---LTATDADE--DNRLHYEITGGNTR------GRFSITSQNGRGLITVAQPLD 430 G+ + + D DE ++ + + N I+ N + + Q LD Sbjct: 144 GSELSVEPPIVVVDRDEGINSEVQMKCLEENDICDIFEVRAVKISDGNYTARVALKQQLD 203 Query: 431 FKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 F+ Y+LT+SA+DS S A + IN+ D + P+F NAPY+A+V E+ P G + Sbjct: 204 FESRPSYILTISASDSALDNRLSSLATISINVIDIQDQPPIFTNAPYSATVPENTPAGVS 263 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI---TTNKLLDRET- 543 +L V A D DVGI +I SL +E H + +P+ G TT++ LDRE Sbjct: 264 ILTVKAVDGDVGIPREIFLSL----EDEPFGHFELVPFGDPRDGTAVLQTTSEPLDRENA 319 Query: 544 ---MSG--YLLTVTAR---DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 +G Y+ ++ A DG +P+ T V I V DV+D++P F + +I E+ Sbjct: 320 EILQNGGVYVFSIRATELIDGAIPAEHSLTRVTIVVTDVDDHQPTFSGPHFNVSITENLA 379 Query: 596 VGTSVS--QVGATDADVGLNGRIHYELDPKDREEGS--FVIDPASGVIRTN---KALDRE 648 G + + D D+G N R YEL +D + F + P RT K L+ Sbjct: 380 NGMPLPGLSIFVDDRDMGENSR--YELSLRDVFNAARVFEVSPTESQGRTPVVVKVLNAS 437 Query: 649 ----SVATHDLKAVAID---GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701 V DL+ D + + V I + D ND+ PVF+ F +EN P Sbjct: 438 RLDYDVVDPDLRKFEFDLVASVKGVEKAKTRVEIHLLDANDNAPVFDQGTYRFTAAENLP 497 Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK 761 + IG ++A D D G V Y +KG N F + G + + LDYE + Sbjct: 498 VDAIIGHVKATDLDSGEFGHVRYVLKGFGADN-FYVNPETGG----VYLLKPLDYEK-QS 551 Query: 762 KYELVIRAASPPLWN-DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD 820 Y L + A + + + VTDVNDN P + + + P V A+D Sbjct: 552 SYSLTVVAIDGGQREANANLFVGVTDVNDNHPNFESKEYSRTIREGAALFEPQFFVRAHD 611 Query: 821 AD----VTDKLQYRILSGNN--ANLILLNETTGSMTLSPQLNTNVPKLATME--VSVTD- 871 AD +++Y I+S N+ N+ + TG + + + + E VS TD Sbjct: 612 ADGPSQGNGRVKYSIVSENSIAGNVFRIEPDTGEIVIQKAARSMDTERGEYELVVSATDF 671 Query: 872 GVNEIKAMMQLSVRL 886 G+ + ++ VR+ Sbjct: 672 GIPPLSNTTRVLVRV 686 Score = 116 bits (279), Expect = 9e-24 Identities = 104/353 (29%), Positives = 158/353 (44%), Gaps = 37/353 (10%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 + QI VLD ND++P F ++Y + E A + VL L+A D D G EV Y ELV Sbjct: 1154 VELQIEVLDVNDNAPEFTQKKYSTVIPENAQIDSFVLQLEAVDADEGLGGEVRY--ELVN 1211 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASL-DREKVARYTVLVKATDQAS- 124 N +F+ID +SG + TR +L + + Y ++V+A D + Sbjct: 1212 EGEAN----------------GLFKIDTKSGLISTRRNLTGKGRAHPYVLIVRAQDNGNQ 1255 Query: 125 -PVSDRLSSTATIHVNI--IDDNDNYPQF-SEKTYTVSVDEDISVTDNPVIAKIKATDAD 180 P LS+ + + I + ND P F S + ++ + +VT PV I + D Sbjct: 1256 MPKQPTLSTDTDVRIYIGDVSANDGVPYFLSPRVGQMANVTENAVTGAPVFQVIASDPDD 1315 Query: 181 VGANS-AIRYAIIGGNTQMQ-FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238 S I Y I+ + F ID+ SG ++ +++D E YR+++ D G P +S Sbjct: 1316 ESTPSGTITYRILPDTPDAEAFVIDAHSGLITTRQSMDRETKDMYRILLEVSDNGQPKQS 1375 Query: 239 NTTQLLINIRDVNDNAPRFYTSL----FQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294 T L I I DV+D+ PRF SV E P G + A D D G NA + Y Sbjct: 1376 ATRILQIAILDVDDHEPRFAREAGAGPLSMSVREEEPAGTIVGNFSALDEDLGENAAIDY 1435 Query: 295 TMTDKDYTGNVDLPITIDPRS---GWVYTSGQLDRETQAKYQLLVTATDGGDP 344 + D GN + TI+ + + T +DRE + L + G+P Sbjct: 1436 VIID----GNNEQLFTIERNNESLAILKTKKPIDREQVESFTLTIKCLKLGEP 1484 Score = 106 bits (254), Expect = 1e-20 Identities = 80/288 (27%), Positives = 136/288 (47%), Gaps = 30/288 (10%) Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 + F ID SG + TR S+DRE Y +L++ +D P + S+T + + I+D +D+ Sbjct: 1335 EAFVIDAHSGLITTRQSMDRETKDMYRILLEVSDNGQP---KQSATRILQIAILDVDDHE 1391 Query: 148 PQFSEKTYTVSVDEDISVTD--NPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205 P+F+ + + + + ++ A D D+G N+AI Y II GN + F+I+ Sbjct: 1392 PRFAREAGAGPLSMSVREEEPAGTIVGNFSALDEDLGENAAIDYVIIDGNNEQLFTIERN 1451 Query: 206 SGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPS---------RSNTTQLLINIR--DVN 251 + ++++KT +D EQV S+ L I+ G P R + + L IN+R D++ Sbjct: 1452 NESLAILKTKKPIDREQVESFTLTIKCLKLGEPGYKFIGDPYDRQDLSHLRINVRVLDID 1511 Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE-----GVNAELT------YTMTDKD 300 DN P+F + NVPI + ++A DAD G++ E Y + Sbjct: 1512 DNLPKFEQPDPTVGIRINVPIDTVVTTLKASDADAEAPPVGLSIENVTFVPQFYKRSRSL 1571 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348 GN+ T++ R+G + T G + + V A + P R A Sbjct: 1572 AVGNLHNLFTLNNRTGELRTGGSFADYVDGYFLMRVMANNSVQPKRQA 1619 >UniRef50_Q9Y5I4 Cluster: Protocadherin alpha C2 precursor; n=23; Euteleostomi|Rep: Protocadherin alpha C2 precursor - Homo sapiens (Human) Length = 1007 Score = 228 bits (558), Expect = 1e-57 Identities = 173/584 (29%), Positives = 266/584 (45%), Gaps = 56/584 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ +LD ND+SP F Y+ V E + G A D D+G N+ Y Sbjct: 135 EVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTY--------E 186 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L+P + V L+ R LDRE+ A + +++ A D P Sbjct: 187 LSPSEHFELDLKPLQENSKVLE-------LVLRKGLDREQAALHHLVLTAVDGGIPAR-- 237 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S TA I V ++D NDN P F + TY V + ED ++ K+ A+D D G+N +RY Sbjct: 238 -SGTAQISVRVLDTNDNSPAFDQSTYRVQLRED--SPPGTLVVKLNASDPDEGSNGELRY 294 Query: 190 AIIGGNTQMQ---FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 ++ + + FSID+ +G+V ++ LDYE+ SY++ ++A D G + ++L++ Sbjct: 295 SLSSYTSDRERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVD 354 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 I DVNDNAP + V EN + + D D G N +++ + Sbjct: 355 IVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGL-------EAT 407 Query: 307 LPITID--PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 LP ++ S + SG LDRE A Y + VTATDGG P ++ T Sbjct: 408 LPFRLNGFGNSYTLVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPP 467 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR-------LHYEITGGNTRGRFSITSQ 417 F+ Y + + E+ PG + T+ ATD DE L EI G SI S Sbjct: 468 SFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSA 527 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAP--VFENAP 473 +G + D+++ R + +TV A D G S T + + D N++AP ++ + Sbjct: 528 SGS--LYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPTST 585 Query: 474 YTASVFE----DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 +++ FE AP G V V A DSD G NA + Y L+ + F + Sbjct: 586 NSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTSDLDL-------FKVELH 638 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 TG I T + + E+ S + LTV RD G PSLS + + ++VVD Sbjct: 639 TGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVD 682 Score = 228 bits (557), Expect = 2e-57 Identities = 177/603 (29%), Positives = 275/603 (45%), Gaps = 27/603 (4%) Query: 92 IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151 +D SGAL +DRE + + ++ + + + V I+D NDN P+F Sbjct: 92 LDLTSGALFVNERIDREALCEQRP--RCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFP 149 Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG---- 207 Y + V E SV A D DVGANS Y + + + + L Sbjct: 150 RPNYQLQVSE--SVAPGARFHIESAQDPDVGANSVQTYEL-SPSEHFELDLKPLQENSKV 206 Query: 208 -DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266 ++ L K LD EQ + LV+ A DGG P+RS T Q+ + + D NDN+P F S ++ + Sbjct: 207 LELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQL 266 Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI-TIDPRSGWVYTSGQLD 325 E+ P G +V++ A D DEG N EL Y+++ YT + + + +ID +G V G LD Sbjct: 267 REDSPPGTLVVKLNASDPDEGSNGELRYSLS--SYTSDRERQLFSIDASTGEVRVIGGLD 324 Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 E + YQ+ V ATD G P + + + E+ P T V Sbjct: 325 YEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIV 384 Query: 386 VTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445 L+ D D + G F + + V+ PLD ++ Y +TV+ATD Sbjct: 385 AVLSVNDQDSGPNRKVSL-GLEATLPFRLNGFGNSYTLVVSGPLDRERVAVYNITVTATD 443 Query: 446 SGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503 G T++ +++ I+D N+ P F Y+ + E+ G + V ATD D NA+ Sbjct: 444 GGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAE 503 Query: 504 ITYS-LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 +TYS L EI V + IN +G++ D E + +TV A+D G P LS Sbjct: 504 VTYSLLEREIQGLPVTSY---VSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLS 560 Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTAN------IMEDALVGTSVSQVGATDADVGLNGRI 616 T + VVD+ND+ P T + + A G V++V A D+D G N + Sbjct: 561 STVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWL 620 Query: 617 HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676 Y L + + F ++ +G IRT + + ES +T +L V D G P S++V + + Sbjct: 621 FYHL-AQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVA 679 Query: 677 IED 679 + D Sbjct: 680 VVD 682 Score = 183 bits (446), Expect = 5e-44 Identities = 166/604 (27%), Positives = 279/604 (46%), Gaps = 37/604 (6%) Query: 309 ITIDPRSGWVYTSGQLDRET--QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 + +D SG ++ + ++DRE + + + L++ P + +A Sbjct: 90 LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSPRFP 149 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADED-NRLH-YEITGG-NTRGRFSITSQNGRGL- 422 P Y+++++E PG +A D D N + YE++ + +N + L Sbjct: 150 RPN-YQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKVLE 208 Query: 423 ITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 + + + LD +Q + L ++A D G RS TA + + + D N+ +P F+ + Y + E Sbjct: 209 LVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQLRE 268 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 D+P GT V+ ++A+D D G N ++ YSLSS S+ Q F I+ TG + LD Sbjct: 269 DSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDR----ERQLFSIDASTGEVRVIGGLD 324 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP-VFKQQLYTANIMEDALVGTS 599 E S Y + V A D G ++ V + +VDVNDN P V LY+ + E+A T Sbjct: 325 YEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSP-VPENATPNTI 383 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 V+ + D D G N ++ L+ + + + V+ + LDRE VA +++ A Sbjct: 384 VAVLSVNDQDSGPNRKVSLGLEATLPFRLNGFGNSYTLVV--SGPLDRERVAVYNITVTA 441 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 DGG P +S + ++I DIND+PP F D + YI EN+ G + ++A DPDE N Sbjct: 442 TDGGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKEN 501 Query: 720 AVVHYS-----IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR--AASP 772 A V YS I+G ++ S+ + GS L + DYE R+ + V SP Sbjct: 502 AEVTYSLLEREIQGLPVTSYVSINSASGS----LYAVNSFDYEKFREFFVTVEAQDKGSP 557 Query: 773 PLWNDVRVEILVTDVNDNA-----PVMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTDK 826 PL + V + V D+ND+A P + F P G +V A D+D Sbjct: 558 PLSSTVTANVYVVDMNDHAPHILYPTSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQN 617 Query: 827 --LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLS 883 L Y + ++ +L + TG + + ++ + V V D G + A + ++ Sbjct: 618 AWLFYHLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAIT 677 Query: 884 VRLI 887 V ++ Sbjct: 678 VAVV 681 >UniRef50_Q9Y5H7 Cluster: Protocadherin alpha 5 precursor; n=15; Eutheria|Rep: Protocadherin alpha 5 precursor - Homo sapiens (Human) Length = 936 Score = 228 bits (558), Expect = 1e-57 Identities = 171/617 (27%), Positives = 283/617 (45%), Gaps = 33/617 (5%) Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 D+ ++ ++G L + +DRE++ R + + + DR + V + D NDN Sbjct: 72 DLLEVNLQNGILFVNSRIDREELCRRRA--ECSIHLEVIVDRPLQVFHVEVAVKDINDNP 129 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 P+FS + + + E + D+ + A+D D+GAN+ +RY + N F +D + Sbjct: 130 PRFSRQEQRLFILES-RMPDSRFPLE-GASDLDIGANAQLRYRL---NPNEYFDLDVKTN 184 Query: 208 D-------VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260 + + L K+LD E+ + +RL++ A DGG P + T QLLIN+ D NDNAP F S Sbjct: 185 EEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKS 244 Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT 320 ++ + EN P G ++++ A DADEG+N E+ Y ++ +V I+ +G + Sbjct: 245 IYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNL-VLDDVKSKFIINSNTGEIKV 303 Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380 +G+LD E Y++ + A D P S + + ED P Sbjct: 304 NGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAP 363 Query: 381 PGTPVVTLTATDADEDNRLHYEITGG---NTRGRFSITSQNGRGLITVAQPLDFKQERRY 437 T + ++ +D D+ + ++T + + T +N L+ + LD + Y Sbjct: 364 LSTVIALISV--SDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLV-LDSALDRESVSVY 420 Query: 438 VLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495 L V+A D G S TA V + + D N+ AP F YT V E+ P G + VSA D Sbjct: 421 ELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARD 480 Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555 +D NA ++YSL E ++ ++G + + LD E + V+ARD Sbjct: 481 ADAQENALVSYSLVERRVGERPL--SSYVSVHAESGKVYALQPLDHEEVELLQFQVSARD 538 Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLY--TANIMEDAL-----VGTSVSQVGATDA 608 GVP L +++ V+D NDN P T + + + G V++V A D Sbjct: 539 AGVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDP 598 Query: 609 DVGLNGRIHYELDPKDREEG-SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 D G N + YEL P F + +G I T ++LD H L + D G PP Sbjct: 599 DSGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPL 658 Query: 668 SSTVIVHIKIEDINDSP 684 ++T V + + + +P Sbjct: 659 TATATVLVSLVESGQAP 675 Score = 214 bits (523), Expect = 3e-53 Identities = 165/553 (29%), Positives = 249/553 (45%), Gaps = 37/553 (6%) Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + ++D+NDN PRF + + E+ A D D G NA+L Y + +Y Sbjct: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEY--- 176 Query: 305 VDLPI-TIDPRSGWV--YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 DL + T + + ++ LDRE +++LLV ATDGG P + T Sbjct: 177 FDLDVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDAND 236 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITG---GNTRGRFSITS 416 F Y V L E+ P GT V+ L A+DADE + + Y + + + +F I S Sbjct: 237 NAPEFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINS 296 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPY 474 G I V LD++ Y + + A D S V + + D N+ P Sbjct: 297 NTGE--IKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTL 354 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 V EDAP+ T + ++S +D D G N Q+T SL + + V+ + ++ Sbjct: 355 FLPVKEDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYY-------SLV 407 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 + LDRE++S Y L VTARDGG PSL T V + V DVNDN P F Q YT + E+ Sbjct: 408 LDSALDRESVSVYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENN 467 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPK---DREEGSFV-IDPASGVIRTNKALDRESV 650 G + V A DAD N + Y L + +R S+V + SG + + LD E V Sbjct: 468 PPGCHIFTVSARDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEV 527 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF-------ESDCLTFYISENSPIG 703 + A D G PP S V + + + D ND+ P ++ + + G Sbjct: 528 ELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAG 587 Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD-YESPRKK 762 + ++RA DPD G NA + Y ++ S + R G E+ T LD E+PR + Sbjct: 588 HVVAKVRAVDPDSGYNAWLSYELQPA--PGSARIPFRVGLYTGEISTTRSLDETEAPRHR 645 Query: 763 YELVIR-AASPPL 774 ++++ PPL Sbjct: 646 LLVLVKDHGEPPL 658 Score = 192 bits (469), Expect = 9e-47 Identities = 119/377 (31%), Positives = 196/377 (51%), Gaps = 10/377 (2%) Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ--INITDANNYAPVFENAPYTASVFE 480 + + + LD ++ + + L V ATD G T VQ IN+ DAN+ AP F+ + Y + E Sbjct: 193 LVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVRLLE 252 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 +AP GT V+ ++A+D+D GIN +I Y S+ + ++ + +F+IN TG I N LD Sbjct: 253 NAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKS----KFIINSNTGEIKVNGELD 308 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 E + Y + + A D LS V + ++DVNDN P + EDA + T + Sbjct: 309 YEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVI 368 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 + + +D D G NG++ L P + ++ + ALDRESV+ ++L A Sbjct: 369 ALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLV-LDSALDRESVSVYELVVTAR 427 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 DGG+P +T V +++ D+ND+ P F T ++ EN+P G I + A D D NA Sbjct: 428 DGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQENA 487 Query: 721 VVHYS-IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR-KKYELVIR-AASPPLWND 777 +V YS ++ S ++ ++ + LD+E ++++ R A PPL ++ Sbjct: 488 LVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSN 547 Query: 778 VRVEILVTDVNDNAPVM 794 V +++ V D NDNAP + Sbjct: 548 VTLQVFVLDENDNAPAL 564 Score = 154 bits (373), Expect = 4e-35 Identities = 114/346 (32%), Positives = 164/346 (47%), Gaps = 30/346 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 INVLD ND++P F+ Y + E A SGT V+ L A+D D G N E+ Y + D Sbjct: 229 INVLDANDNAPEFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLD-- 286 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 V+ F I+ +G + LD E Y + + A D++ + L Sbjct: 287 --------------DVKSKFIINSNTGEIKVNGELDYEDYNSYEINIDAMDKS---TFPL 329 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S + V ++D NDN P+ + T + V ED + + VIA I +D D GAN + + Sbjct: 330 SGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPL--STVIALISVSDRDSGANGQVTCS 387 Query: 191 IIGGNTQMQFS-IDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 ++ + F + + SLV LD E V Y LV+ A+DGGSPS T + + + Sbjct: 388 LM---PHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDGGSPSLWATASVSVEV 444 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 DVNDNAP F + V EN P G I V A DAD NA ++Y++ ++ G L Sbjct: 445 ADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVER-RVGERPL 503 Query: 308 P--ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 +++ SG VY LD E Q V+A D G PP + T Sbjct: 504 SSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVT 549 Score = 57.2 bits (132), Expect = 6e-06 Identities = 67/281 (23%), Positives = 123/281 (43%), Gaps = 18/281 (6%) Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV-IDPASGVIRTNKALDR 647 +I E+A GT V ++ A D + L + + G + ++ +G++ N +DR Sbjct: 33 SIPEEAKHGTFVGRI-AQDLGLELAELVPRLFRVASKGRGDLLEVNLQNGILFVNSRIDR 91 Query: 648 ESVATHDLK-AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706 E + + ++ ++ V + ++DIND+PP F +I E+ + Sbjct: 92 EELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNPPRFSRQEQRLFILESRMPDSRF 151 Query: 707 GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA---ELVTMVDLDYESPRKKY 763 A D D G NA + Y + + + F L+ + ++ ELV LD E ++ Sbjct: 152 PLEGASDLDIGANAQLRYRL---NPNEYFDLDVKTNEEETNFLELVLRKSLDREETQEHR 208 Query: 764 ELVIR--AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYD 820 LVI P L V++ I V D NDNAP D I + P G ++ A D Sbjct: 209 LLVIATDGGKPELTGTVQLLINVLDANDNAPEF-DKSIYNVRLLENAPSGTLVIKLNASD 267 Query: 821 AD--VTDKLQY---RILSGNNANLILLNETTGSMTLSPQLN 856 AD + ++ Y ++ + + ++N TG + ++ +L+ Sbjct: 268 ADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELD 308 >UniRef50_P34616 Cluster: Cadherin-3 precursor; n=13; root|Rep: Cadherin-3 precursor - Caenorhabditis elegans Length = 3343 Score = 228 bits (557), Expect = 2e-57 Identities = 199/751 (26%), Positives = 342/751 (45%), Gaps = 72/751 (9%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F I G + T + LD E + Y + A ST+ + +++ D+ND P+ Sbjct: 1598 FTISPFDGTIFTNSPLDFENIKTYRFNITAG----------KSTSQVIIHVTDENDEAPR 1647 Query: 150 F-SEKTYTVSVDEDISVTDNP-VIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 F + + V E++ P +I A D D G N + Y+I+ GNT + F+++S +G Sbjct: 1648 FITGDVVNLKVLEELDTVSYPLIIGSSIAEDLDEGQNGLVTYSILSGNTSL-FAVNSTTG 1706 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 D+ + LD E+ + L+I A+D G PS S T+++LI++ D+NDN P F S + +S Sbjct: 1707 DILSLIPLDREESSLHELLIEAKDAGIPSLSATSKILIHVGDINDNTPEFELSSYFIKIS 1766 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 EN IG I+R+ A D D+ +AEL Y++ D + +P I+ +GW+ +G+++RE Sbjct: 1767 ENSKIGSKIIRILATDKDK--DAELQYSLESND---EITIPFRINVATGWITVAGKVNRE 1821 Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387 +++ V TDG +S+ ++ + + + Sbjct: 1822 ENEEFRFFVKVTDG---EKSSKVIVEIHVEDFNDNHPMINDRNSDIFVPDPTRSVEIIHV 1878 Query: 388 LTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447 + D D+ + L + + N S+NG IT+ PL + + V+ +D Sbjct: 1879 INVHDLDKSDHLKFSLNNSNLN-----LSENGE--ITLKSPL----QTAVPVRVTVSDDA 1927 Query: 448 GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507 G M + + + PVF T SV E L V + D I YS Sbjct: 1928 GHV-AFMEYLFHPHSRKHFPVFVEKLDTVSVREH---DEQELAVFKANGD-----SIRYS 1978 Query: 508 LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG-GVPSLSDTTD 566 + S S+ H + + TG + T LD E S L+ + A LS T Sbjct: 1979 IVSRCSD----HLEME----KSTGILKTKSSLDAEEYSECLVFIIATTYFDNKPLSTITK 2030 Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDA---LVGTSVSQVGATDADVGLNGRIHYELDPK 623 I +VD+NDN P F QQLY N+ E++ L+G +++ D+ + R+ YE+ Sbjct: 2031 ATIKIVDINDNSPRFDQQLYRFNVTENSGPKLIGHVIAR------DIDRSSRVFYEIVGG 2084 Query: 624 DREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS 683 D V + SG I + + LDRE+ + + L AID G P + V + + D +D+ Sbjct: 2085 DANHEFMVTE--SGQIESVRDLDRETKSEYHLIVEAIDDGKPRRRGNTTVIVTVLDEDDN 2142 Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 P F S + E+ IG + ++ A D DE N + + GG + F ++ G Sbjct: 2143 APRF-SRIFHVEVPEDVRIGEPVIQLSASDADEHSNH--RFELDGGGEGIPFRVDENTG- 2198 Query: 744 DKAELVTMVD-LDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFN 802 +V + D LD+E ++ Y + ++ + + + V DVNDNAP+ + + +F Sbjct: 2199 ----MVFVNDSLDFEK-KQSYRIKVKLTDGAWLIETSLFVNVKDVNDNAPIFEKPEYLFI 2253 Query: 803 NYKDCFPVGPFGRVPAYDADVTDKLQYRILS 833 + ++ +G F D++ K++Y + S Sbjct: 2254 SEENSAEIGQF-HASDMDSENNGKIRYSVTS 2283 Score = 157 bits (380), Expect = 5e-36 Identities = 168/700 (24%), Positives = 309/700 (44%), Gaps = 67/700 (9%) Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259 F+I G + LD+E +++YR I A +T+Q++I++ D ND APRF T Sbjct: 1598 FTISPFDGTIFTNSPLDFENIKTYRFNITAG-------KSTSQVIIHVTDENDEAPRFIT 1650 Query: 260 S-LFQESVSENVP-IGYSIVRVQ--AYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315 + V E + + Y ++ A D DEG N +TY++ +GN L ++ + Sbjct: 1651 GDVVNLKVLEELDTVSYPLIIGSSIAEDLDEGQNGLVTYSIL----SGNTSL-FAVNSTT 1705 Query: 316 GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375 G + + LDRE + ++LL+ A D G P SAT+ F Y +++ Sbjct: 1706 GDILSLIPLDREESSLHELLIEAKDAGIPSLSATSKILIHVGDINDNTPEFELSSYFIKI 1765 Query: 376 AEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435 +E+ G+ ++ + ATD D+D L Y + N G ITVA ++ ++ Sbjct: 1766 SENSKIGSKIIRILATDKDKDAELQYSLES-NDEITIPFRINVATGWITVAGKVNREENE 1824 Query: 436 RYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495 + V TD G +S +V+I++ D N+ P+ + + +F P + ++ Sbjct: 1825 EFRFFVKVTD-GEKSSKVIVEIHVEDFNDNHPMINDR--NSDIFVPDPTRSVEIIHVINV 1881 Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555 D+ + + +SL++ N + + G IT L +T +TV+ Sbjct: 1882 HDLDKSDHLKFSLNNSNLNLS------------ENGEITLKSPL--QTAVPVRVTVSDDA 1927 Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615 G V + + + PVF ++L T ++ E +V + + R Sbjct: 1928 GHVAFME-----YLFHPHSRKHFPVFVEKLDTVSVREHDEQELAVFKANGDSIRYSIVSR 1982 Query: 616 IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG-GTPPQSSTVIVH 674 L+ ++ ++G+++T +LD E + + +A P S+ Sbjct: 1983 CSDHLE----------MEKSTGILKTKSSLDAEEYSECLVFIIATTYFDNKPLSTITKAT 2032 Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734 IKI DIND+ P F+ F ++ENS IG + A D D V Y I GGD ++ Sbjct: 2033 IKIVDINDNSPRFDQQLYRFNVTENSG-PKLIGHVIARDIDRSSR--VFYEIVGGDANHE 2089 Query: 735 FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNA 791 F + ++ ++ ++ DLD E+ + +Y L++ A P + V + V D +DNA Sbjct: 2090 FMV-----TESGQIESVRDLDRET-KSEYHLIVEAIDDGKPRRRGNTTVIVTVLDEDDNA 2143 Query: 792 PVMKDFQIIFN-NYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSM 849 P F IF+ + +G P ++ A DAD ++ + G ++E TG + Sbjct: 2144 P---RFSRIFHVEVPEDVRIGEPVIQLSASDADEHSNHRFELDGGGEGIPFRVDENTGMV 2200 Query: 850 TLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889 ++ L+ + ++V +TDG I+ + ++V+ + + Sbjct: 2201 FVNDSLDFEKKQSYRIKVKLTDGAWLIETSLFVNVKDVND 2240 Score = 153 bits (370), Expect = 9e-35 Identities = 191/751 (25%), Positives = 314/751 (41%), Gaps = 70/751 (9%) Query: 2 SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEV--- 58 S P IH I+VLD ND+SP+F + + E A G V ATD D GKN + Sbjct: 96 SPPSIIHILIDVLDVNDNSPIFPIDVQRVEIPETAPIGWRVQISGATDPDEGKNGTIGKY 155 Query: 59 EYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVK 118 E L T DT++P + + DG +T LDRE Y++ + Sbjct: 156 ELVDSLATVDTMSPFG--------------IVQSDGFLFLEVT-GKLDRETRDLYSMRLT 200 Query: 119 ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178 A DQ P LSS+ +++ I+D NDN P F ++ T++ + N + + ATD Sbjct: 201 AIDQGVP---ELSSSCHLNILILDINDNPPNFGIRSLTLNWNG----LPNTKLFSLNATD 253 Query: 179 ADVGANSAIRYAII-GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237 D NS + Y I+ G T FSI S + LV + E ++ V+ A+D G P Sbjct: 254 LDSNENSLLTYRILPSGPTSEMFSI---SDENILVTQNNTECLQRCEFVVEARDSGVPPL 310 Query: 238 SNTTQLLINIRDVNDNAP----RFYTSLFQESVSENVPI-GYSIVRVQAYDADEGVNAEL 292 S T +++N+ N++ P RFY S + + + + G ++ + D+D + A Sbjct: 311 STTLNIVVNMEYGNEHEPNINIRFYPSDYPFIIVQPEDVNGKTLAILSITDSDGPLGANS 370 Query: 293 TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSATAT 351 T + + + L I +S + T ++ Q +Y L A DG P R Sbjct: 371 TIWIENGNEQSIFSL---ISRQSINILTVKHVENANQEQYILEFRANDGQSPADRITRKE 427 Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGR 411 + + V + +D PG+ V + D +E+ + Sbjct: 428 LKIFFKKYVKSTQIHVERESHVTVEKDTVPGSFVAHVETNCTD---MCSFELANSDV--- 481 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVF-E 470 F I NG I V + + Y L + R + +A+ + V E Sbjct: 482 FKIDPFNG---IIVTSSILPEGVTSYHLPI-------RIHLPPPSTQLVEADVFVKVIQE 531 Query: 471 NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 + P ++PI T DV + I ++I + + + P Sbjct: 532 SVPKNLIRSSESPIHLKRAYTFTTWQDVSLGTVIGRLPKAQI--YSTIDTVSELGVFPD- 588 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590 G++ K + + ++ L VT + S T + V +N + P+ Q+ ++ Sbjct: 589 GSVFVGKTITSDFVT---LPVTLVNRNTTQTSIIT---LIVKPLNQHSPIC--QITEIHV 640 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGVIRTNKALDRES 649 +E+A +GT ++ A D D GL+G + Y+ L D +G F +D SG +R+ KA D E Sbjct: 641 LENAPIGTIFGRIQARDEDSGLSGVVSYKILTKSDDYDGIFHLDSTSGSLRSLKAFDAEK 700 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 ++ + A D GTP +++ I IED+ND+ P F S T IS S T+ + Sbjct: 701 KRSYTFEYEAKDLGTPSKTTNCPATIFIEDVNDNVPKFGSRYYTATISGKS--NETVAIV 758 Query: 710 RAHDPD-EGPNAVVHYSIKGGDDSNSFSLET 739 +A+D D + N + Y + D ET Sbjct: 759 QANDNDVDVKNQKLQYHLLNYHDFFQLDKET 789 Score = 135 bits (327), Expect = 1e-29 Identities = 129/423 (30%), Positives = 196/423 (46%), Gaps = 46/423 (10%) Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205 ++P F EK TVSV E D +A KA +IRY+I+ + ++ Sbjct: 1944 HFPVFVEKLDTVSVREH----DEQELAVFKAN------GDSIRYSIVSRCSD-HLEMEKS 1992 Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDG-GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 +G + +LD E+ + I A + S T+ I I D+NDN+PRF L++ Sbjct: 1993 TGILKTKSSLDAEEYSECLVFIIATTYFDNKPLSTITKATIKIVDINDNSPRFDQQLYRF 2052 Query: 265 SVSENVPIGYSIV-RVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323 +V+EN G ++ V A D D ++ + Y + D N + +T SG + + Sbjct: 2053 NVTENS--GPKLIGHVIARDIDR--SSRVFYEIVGGD--ANHEFMVT---ESGQIESVRD 2103 Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383 LDRET+++Y L+V A D G P R T F + VE+ ED G Sbjct: 2104 LDRETKSEYHLIVEAIDDGKPRRRGNTTVIVTVLDEDDNAPRFSR-IFHVEVPEDVRIGE 2162 Query: 384 PVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443 PV+ L+A+DADE + +E+ GG F + G++ V LDF++++ Y + V Sbjct: 2163 PVIQLSASDADEHSNHRFELDGGGEGIPFRV--DENTGMVFVNDSLDFEKKQSYRIKVKL 2220 Query: 444 TDSGGRSDTAMVQINITDANNYAPVFENAPYT-ASVFEDAPIGTTVLVVSATDSDVGINA 502 TD +T++ +N+ D N+ AP+FE Y S A IG A+D D N Sbjct: 2221 TDGAWLIETSLF-VNVKDVNDNAPIFEKPEYLFISEENSAEIGQ----FHASDMDSENNG 2275 Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITT-NKLLDRETMSGYLLTVTARDGGVPSL 561 +I YS++S F I P TG ++ + L + MS L VTA D GVP L Sbjct: 2276 KIRYSVTS-----------PYFKIEPSTGVLSRFRQQLPQPLMS---LKVTATDHGVPRL 2321 Query: 562 SDT 564 T Sbjct: 2322 QKT 2324 Score = 131 bits (316), Expect = 3e-28 Identities = 161/669 (24%), Positives = 284/669 (42%), Gaps = 87/669 (13%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+V D ND++P FE+ Y + E + G+ ++ + ATD+D K+AE++Y++E Sbjct: 1744 IHVGDINDNTPEFELSSYFIKISENSKIGSKIIRILATDKD--KDAELQYSLES------ 1795 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N E + FRI+ +G + ++RE+ + VK TD Sbjct: 1796 NDE------------ITIPFRINVATGWITVAGKVNREENEEFRFFVKVTDGEK------ 1837 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SS + +++ D NDN+P +++ + V + + +I I D D + ++++ Sbjct: 1838 SSKVIVEIHVEDFNDNHPMINDRNSDIFVPDPTRSVE--IIHVINVHDLD--KSDHLKFS 1893 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + N + S +G+++L L + R+ + + D G + + L + Sbjct: 1894 LNNSNLNL-----SENGEITLKSPL--QTAVPVRVTV-SDDAGHVA---FMEYLFHPHS- 1941 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 + P F L SV E+ ++ + + + + +D + Sbjct: 1942 RKHFPVFVEKLDTVSVREHDEQELAVFKANG----DSIRYSIVSRCSDH---------LE 1988 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD-PPRSATATXXXXXXXXXXXXXXFMPG 369 ++ +G + T LD E ++ + + AT D P S F Sbjct: 1989 MEKSTGILKTKSSLDAEEYSECLVFIIATTYFDNKPLSTITKATIKIVDINDNSPRFDQQ 2048 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 Y + E+ P + + A D D +R+ YEI GG+ F +T G I + L Sbjct: 2049 LYRFNVTENSGPKL-IGHVIARDIDRSSRVFYEIVGGDANHEFMVTES---GQIESVRDL 2104 Query: 430 DFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 D + + Y L V A D G R V + + D ++ AP F + V ED IG Sbjct: 2105 DRETKSEYHLIVEAIDDGKPRRRGNTTVIVTVLDEDDNAPRFSRI-FHVEVPEDVRIGEP 2163 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 V+ +SA+D+D N + + L E + F ++ TG + N LD E Y Sbjct: 2164 VIQLSASDADEHSNHR--FELDG--GGEGIP-----FRVDENTGMVFVNDSLDFEKKQSY 2214 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 + V DG L +T+ + ++V DVNDN P+F++ Y E++ + Q A+D Sbjct: 2215 RIKVKLTDGAW--LIETS-LFVNVKDVNDNAPIFEKPEYLFISEENS---AEIGQFHASD 2268 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVI-RTNKALDRESVATHDLKAVAIDGGTPP 666 D NG+I Y + F I+P++GV+ R + L + ++ LK A D G P Sbjct: 2269 MDSENNGKIRYSVTSP-----YFKIEPSTGVLSRFRQQLPQPLMS---LKVTATDHGVPR 2320 Query: 667 QSSTVIVHI 675 TV+ H+ Sbjct: 2321 LQKTVLAHL 2329 Score = 118 bits (285), Expect = 2e-24 Identities = 147/551 (26%), Positives = 246/551 (44%), Gaps = 56/551 (10%) Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 QFSE+T SV ED + N +I + +A++G Y + GN++++F +L + Sbjct: 26 QFSEETIKFSVSEDAKL--NTIIGHL---EAEIGYT----YRLSRGNSKIKFDEQTL--E 74 Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268 +S+ LD E + ++I S + +LI++ DVNDN+P F + + + E Sbjct: 75 LSVSSPLDRESENAIDMLIIT------SPPSIIHILIDVLDVNDNSPIFPIDVQRVEIPE 128 Query: 269 NVPIGYSIVRVQAYDADEGVNAEL-TYTMTDKDYTGNVDLPITIDPRSGWVY--TSGQLD 325 PIG+ + A D DEG N + Y + D T + P I G+++ +G+LD Sbjct: 129 TAPIGWRVQISGATDPDEGKNGTIGKYELVDSLATVDTMSPFGIVQSDGFLFLEVTGKLD 188 Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 RET+ Y + +TA D G P S++ F G + L + P T + Sbjct: 189 RETRDLYSMRLTAIDQGVPELSSSCHLNILILDINDNPPNF--GIRSLTLNWNGLPNTKL 246 Query: 386 VTLTATDAD--EDNRLHYEI-TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 +L ATD D E++ L Y I G T FSI+ +N ++ + Q +V V Sbjct: 247 FSLNATDLDSNENSLLTYRILPSGPTSEMFSISDEN---ILVTQNNTECLQRCEFV--VE 301 Query: 443 ATDSG--GRSDTAMVQINITDANNYAP----VFENAPYTASVFEDAPI-GTTVLVVSATD 495 A DSG S T + +N+ N + P F + Y + + + G T+ ++S TD Sbjct: 302 ARDSGVPPLSTTLNIVVNMEYGNEHEPNINIRFYPSDYPFIIVQPEDVNGKTLAILSITD 361 Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555 SD + A T + E NE +I+ Q+ I T K ++ Y+L A D Sbjct: 362 SDGPLGANSTIWI--ENGNEQSIFS----LISRQSINILTVKHVENANQEQYILEFRAND 415 Query: 556 GGVPSLSDT-TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614 G P+ T +++I + + ++ + +D + G+ V+ V D+ Sbjct: 416 GQSPADRITRKELKIFFKKYVKSTQIHVERESHVTVEKDTVPGSFVAHVETNCTDM---- 471 Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674 +EL D F IDP +G+I T+ L E V ++ L + I PP + V Sbjct: 472 -CSFELANSD----VFKIDPFNGIIVTSSILP-EGVTSYHL-PIRIH-LPPPSTQLVEAD 523 Query: 675 IKIEDINDSPP 685 + ++ I +S P Sbjct: 524 VFVKVIQESVP 534 Score = 116 bits (278), Expect = 1e-23 Identities = 108/375 (28%), Positives = 165/375 (44%), Gaps = 38/375 (10%) Query: 517 VAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVND 576 + +D F I+P G I TN LD E + Y +TA T+ V I V D ND Sbjct: 1591 IQDNDYNFTISPFDGTIFTNSPLDFENIKTYRFNITAG-------KSTSQVIIHVTDEND 1643 Query: 577 NEPVF-KQQLYTANIMED-------ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG 628 P F + ++E+ ++G+S+ A D D G NG + Y + Sbjct: 1644 EAPRFITGDVVNLKVLEELDTVSYPLIIGSSI----AEDLDEGQNGLVTYSI--LSGNTS 1697 Query: 629 SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688 F ++ +G I + LDRE + H+L A D G P S+T + I + DIND+ P FE Sbjct: 1698 LFAVNSTTGDILSLIPLDREESSLHELLIEAKDAGIPSLSATSKILIHVGDINDNTPEFE 1757 Query: 689 SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD-SNSFSLETRQGSDKAE 747 ISENS IG+ I I A D D+ +A + YS++ D+ + F + G Sbjct: 1758 LSSYFIKISENSKIGSKIIRILATDKDK--DAELQYSLESNDEITIPFRINVATG----- 1810 Query: 748 LVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC 807 +T+ +++ ++ + V VEI V D NDN P++ D Sbjct: 1811 WITVAGKVNREENEEFRFFVKVTDGEKSSKVIVEIHVEDFNDNHPMINDRNSDIFVPDPT 1870 Query: 808 FPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867 V + +D D +D L++ + NN+NL L G +TL L T VP + V Sbjct: 1871 RSVEIIHVINVHDLDKSDHLKFSL---NNSNLNL--SENGEITLKSPLQTAVP----VRV 1921 Query: 868 SVTDGVNEIKAMMQL 882 +V+D + M L Sbjct: 1922 TVSDDAGHVAFMEYL 1936 Score = 111 bits (268), Expect = 2e-22 Identities = 181/743 (24%), Positives = 291/743 (39%), Gaps = 80/743 (10%) Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI-RYAIIGG 194 I ++++D NDN P F V + E + I+ ATD D G N I +Y ++ Sbjct: 103 ILIDVLDVNDNSPIFPIDVQRVEIPETAPIGWRVQISG--ATDPDEGKNGTIGKYELVDS 160 Query: 195 ----NTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 +T F I G + L T LD E Y + + A D G P S++ L I I Sbjct: 161 LATVDTMSPFGIVQSDGFLFLEVTGKLDRETRDLYSMRLTAIDQGVPELSSSCHLNILIL 220 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D+NDN P F + +++ N + + A D D N+ LTY + T + Sbjct: 221 DINDNPPNF--GIRSLTLNWNGLPNTKLFSLNATDLDSNENSLLTYRILPSGPTSEM--- 275 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX----X 364 +I + V Q + E + + +V A D G PP S T Sbjct: 276 FSISDENILVT---QNNTECLQRCEFVVEARDSGVPPLSTTLNIVVNMEYGNEHEPNINI 332 Query: 365 XFMPGQYEVELAEDEPP-GTPVVTLTATDADEDNRLHYEI--TGGNTRGRFSITSQNGRG 421 F P Y + + E G + L+ TD+D + I GN + FS+ S+ Sbjct: 333 RFYPSDYPFIIVQPEDVNGKTLAILSITDSDGPLGANSTIWIENGNEQSIFSLISRQSIN 392 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 ++TV + QE+ Y+L A D +D IT F+ + + + Sbjct: 393 ILTVKHVENANQEQ-YILEFRANDGQSPAD------RIT-RKELKIFFKKYVKSTQIHVE 444 Query: 482 APIGTTVLVVSATDSDVG-INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 TV + S V + T S E++N V F I+P G I T+ +L Sbjct: 445 RESHVTVEKDTVPGSFVAHVETNCTDMCSFELANSDV------FKIDPFNGIIVTSSILP 498 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVD-------VNDNE-PVFKQQLYTANIME 592 E ++ Y L + + DV + V+ + +E P+ ++ YT + Sbjct: 499 -EGVTSYHLPIRIHLPPPSTQLVEADVFVKVIQESVPKNLIRSSESPIHLKRAYTFTTWQ 557 Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652 D +GT + ++ +I+ +D E G F G + K + + V Sbjct: 558 DVSLGTVIGRLP--------KAQIYSTIDTVS-ELGVF----PDGSVFVGKTITSDFVT- 603 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 L ++ T + T I+ + ++ +N P+ + ++ EN+PIGT G I+A Sbjct: 604 --LPVTLVNRNT---TQTSIITLIVKPLNQHSPICQ--ITEIHVLENAPIGTIFGRIQAR 656 Query: 713 DPDEGPNAVVHYSI--KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIR- 768 D D G + VV Y I K D F L++ GS L ++ D E R +E + Sbjct: 657 DEDSGLSGVVSYKILTKSDDYDGIFHLDSTSGS----LRSLKAFDAEKKRSYTFEYEAKD 712 Query: 769 AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV-TDKL 827 +P + I + DVNDN P + D DV KL Sbjct: 713 LGTPSKTTNCPATIFIEDVNDNVPKFGSRYYTATISGKSNETVAIVQANDNDVDVKNQKL 772 Query: 828 QYRILSGNNANLILLNETTGSMT 850 QY +L N + L++ TG +T Sbjct: 773 QYHLL--NYHDFFQLDKETGKVT 793 Score = 103 bits (247), Expect = 7e-20 Identities = 95/350 (27%), Positives = 153/350 (43%), Gaps = 26/350 (7%) Query: 401 YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT 460 Y ++ GN++ +F + ++V+ PLD + E + + + + I++ Sbjct: 57 YRLSRGNSKIKFDEQTLE----LSVSSPLDRESENAIDMLIITSPPS----IIHILIDVL 108 Query: 461 DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI-TYSLSSEISNEAVAH 519 D N+ +P+F + E APIG V + ATD D G N I Y L + + A Sbjct: 109 DVNDNSPIFPIDVQRVEIPETAPIGWRVQISGATDPDEGKNGTIGKYEL---VDSLATVD 165 Query: 520 HDQQFVINPQTGAI---TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVND 576 F I G + T KL DRET Y + +TA D GVP LS + + I ++D+ND Sbjct: 166 TMSPFGIVQSDGFLFLEVTGKL-DRETRDLYSMRLTAIDQGVPELSSSCHLNILILDIND 224 Query: 577 NEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS 636 N P F + T N + L T + + ATD D N + Y + P F I + Sbjct: 225 NPPNFGIRSLTLN--WNGLPNTKLFSLNATDLDSNENSLLTYRILPSGPTSEMFSISDEN 282 Query: 637 GVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP-----VFESDC 691 ++ N + E + + A D G PP S+T+ + + +E N+ P + SD Sbjct: 283 ILVTQN---NTECLQRCEFVVEARDSGVPPLSTTLNIVVNMEYGNEHEPNINIRFYPSDY 339 Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741 + G T+ + D D A I+ G++ + FSL +RQ Sbjct: 340 PFIIVQPEDVNGKTLAILSITDSDGPLGANSTIWIENGNEQSIFSLISRQ 389 Score = 85.8 bits (203), Expect = 2e-14 Identities = 110/435 (25%), Positives = 185/435 (42%), Gaps = 39/435 (8%) Query: 468 VFENAPYTASVFEDAPIGTTVL----VVSATDSDVGI---NAQITYSLSSEISNEAVAHH 520 +++N P F+D I V V+ D++ + N + ++SEI + Sbjct: 1434 IYDNRPPFKVHFDDVTIEFQVTQKLRAVTCEDAEFWMFFGNEDVGMLIASEIVTWRIVPQ 1493 Query: 521 --DQQFVINPQTGAI-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577 F I+P TG I +T ++ + + DG D + I +N Sbjct: 1494 IGSDSFKIDPITGIIQSTPNTKPTSDIAKLKIQAISYDGERVGFCDVK-IHIDKAAFVEN 1552 Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637 V + NI E A T V ++ A GL G + + + D +F I P G Sbjct: 1553 V-VLSNGTFEFNISETADRFTEVGKIVILGA--GLEGSV-FRIQDNDY---NFTISPFDG 1605 Query: 638 VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697 I TN LD E++ T+ A +S VI+H+ E+ +++P D + + Sbjct: 1606 TIFTNSPLDFENIKTYRFNITA-----GKSTSQVIIHVTDEN-DEAPRFITGDVVNLKVL 1659 Query: 698 ENSPIGT---TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDL 754 E + IG A D DEG N +V YSI G+ S F++ + G ++++++ L Sbjct: 1660 EELDTVSYPLIIGSSIAEDLDEGQNGLVTYSILSGNTS-LFAVNSTTG----DILSLIPL 1714 Query: 755 DYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811 D E +EL+I A P L ++ I V D+NDN P + F + +G Sbjct: 1715 DREES-SLHELLIEAKDAGIPSLSATSKILIHVGDINDNTPEF-ELSSYFIKISENSKIG 1772 Query: 812 P-FGRVPAYDADVTDKLQYRILSGNNANL-ILLNETTGSMTLSPQLNTNVPKLATMEVSV 869 R+ A D D +LQY + S + + +N TG +T++ ++N + V V Sbjct: 1773 SKIIRILATDKDKDAELQYSLESNDEITIPFRINVATGWITVAGKVNREENEEFRFFVKV 1832 Query: 870 TDGVNEIKAMMQLSV 884 TDG K ++++ V Sbjct: 1833 TDGEKSSKVIVEIHV 1847 Score = 83.4 bits (197), Expect = 8e-14 Identities = 81/287 (28%), Positives = 130/287 (45%), Gaps = 29/287 (10%) Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 D TI P G ++T+ LD E Y+ +TA +T+ Sbjct: 1595 DYNFTISPFDGTIFTNSPLDFENIKTYRFNITA-------GKSTSQVIIHVTDENDEAPR 1647 Query: 366 FMPGQ-YEVELAED-EPPGTPVV--TLTATDADE--DNRLHYEITGGNTRGRFSITSQNG 419 F+ G +++ E+ + P++ + A D DE + + Y I GNT F++ S G Sbjct: 1648 FITGDVVNLKVLEELDTVSYPLIIGSSIAEDLDEGQNGLVTYSILSGNT-SLFAVNSTTG 1706 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTAS 477 L + PLD ++ + L + A D+G S T+ + I++ D N+ P FE + Y Sbjct: 1707 DILSLI--PLDREESSLHELLIEAKDAGIPSLSATSKILIHVGDINDNTPEFELSSYFIK 1764 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 + E++ IG+ ++ + ATD D +A++ YSL SN+ + F IN TG IT Sbjct: 1765 ISENSKIGSKIIRILATDKDK--DAELQYSLE---SNDEIT---IPFRINVATGWITVAG 1816 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584 ++RE + V DG S VEI V D NDN P+ + Sbjct: 1817 KVNREENEEFRFFVKVTDG---EKSSKVIVEIHVEDFNDNHPMINDR 1860 Score = 69.3 bits (162), Expect = 1e-09 Identities = 60/187 (32%), Positives = 91/187 (48%), Gaps = 21/187 (11%) Query: 170 VIAKIKATDADVGANSAIRYAIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVI 227 + +I+A D D G + + Y I+ + F +DS SG + +K D E+ RSY Sbjct: 649 IFGRIQARDEDSGLSGVVSYKILTKSDDYDGIFHLDSTSGSLRSLKAFDAEKKRSYTFEY 708 Query: 228 RAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG 287 A+D G+PS++ I I DVNDN P+F + + ++S ++ VQA D D Sbjct: 709 EAKDLGTPSKTTNCPATIFIEDVNDNVPKFGSRYYTATISGK--SNETVAIVQANDNDVD 766 Query: 288 V-NAELTYTM--------TDKDYTGNV----DLPITIDPRSGWVYTSGQLDRE--TQAKY 332 V N +L Y + DK+ TG V D+P+T R ++ +D E Q+K Sbjct: 767 VKNQKLQYHLLNYHDFFQLDKE-TGKVTTIQDVPMTWQ-RLNISISAVNMDSERFLQSKT 824 Query: 333 QLLVTAT 339 LLVT T Sbjct: 825 FLLVTVT 831 Score = 66.1 bits (154), Expect = 1e-08 Identities = 59/198 (29%), Positives = 92/198 (46%), Gaps = 29/198 (14%) Query: 17 NDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAX 76 N HSP+ ++ E V E A GT ++A D+D G + V Y I L +D + Sbjct: 627 NQHSPICQIT--EIHVLENAPIGTIFGRIQARDEDSGLSGVVSYKI-LTKSDDYD----- 678 Query: 77 XXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATI 136 +F +D SG+L + + D EK YT +A D +P S + ATI Sbjct: 679 -----------GIFHLDSTSGSLRSLKAFDAEKKRSYTFEYEAKDLGTP-SKTTNCPATI 726 Query: 137 HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA-NSAIRYAIIGGN 195 + D NDN P+F + YT + IS N +A ++A D DV N ++Y ++ N Sbjct: 727 FIE--DVNDNVPKFGSRYYTAT----ISGKSNETVAIVQANDNDVDVKNQKLQYHLL--N 778 Query: 196 TQMQFSIDSLSGDVSLVK 213 F +D +G V+ ++ Sbjct: 779 YHDFFQLDKETGKVTTIQ 796 Score = 64.9 bits (151), Expect = 3e-08 Identities = 79/317 (24%), Positives = 127/317 (40%), Gaps = 34/317 (10%) Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640 F ++ ++ EDA + T + G +A++G R+ R D + + Sbjct: 27 FSEETIKFSVSEDAKLNTII---GHLEAEIGYTYRL-------SRGNSKIKFDEQTLELS 76 Query: 641 TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE--DINDSPPVFESDCLTFYISE 698 + LDRES D+ + +PP I+HI I+ D+ND+ P+F D I E Sbjct: 77 VSSPLDRESENAIDMLIIT----SPPS----IIHILIDVLDVNDNSPIFPIDVQRVEIPE 128 Query: 699 NSPIGTTIGEIRAHDPDEGPNAVV-HY----SIKGGDDSNSFSLETRQGSDKAELVTMVD 753 +PIG + A DPDEG N + Y S+ D + F + G E+ +D Sbjct: 129 TAPIGWRVQISGATDPDEGKNGTIGKYELVDSLATVDTMSPFGIVQSDGFLFLEVTGKLD 188 Query: 754 LDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF 813 + I P L + + IL+ D+NDN P + N + P Sbjct: 189 RETRDLYSMRLTAIDQGVPELSSSCHLNILILDINDNPPNFGIRSLTLN--WNGLPNTKL 246 Query: 814 GRVPAYDADVTDK--LQYRIL-SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVT 870 + A D D + L YRIL SG + + +++ L Q NT + V Sbjct: 247 FSLNATDLDSNENSLLTYRILPSGPTSEMFSISDEN---ILVTQNNTECLQRCEFVVEAR 303 Query: 871 D-GVNEIKAMMQLSVRL 886 D GV + + + V + Sbjct: 304 DSGVPPLSTTLNIVVNM 320 Score = 50.8 bits (116), Expect = 5e-04 Identities = 55/256 (21%), Positives = 98/256 (38%), Gaps = 15/256 (5%) Query: 239 NTTQ---LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295 NTTQ + + ++ +N ++P + + V EN PIG R+QA D D G++ ++Y Sbjct: 612 NTTQTSIITLIVKPLNQHSP--ICQITEIHVLENAPIGTIFGRIQARDEDSGLSGVVSYK 669 Query: 296 MTDK--DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353 + K DY G L D SG + + D E + Y A D G P ++ Sbjct: 670 ILTKSDDYDGIFHL----DSTSGSLRSLKAFDAEKKRSYTFEYEAKDLGTPSKTTNCPAT 725 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN-RLHYEITGGNTRGRF 412 F Y ++ +V D D N +L Y + N F Sbjct: 726 IFIEDVNDNVPKFGSRYYTATISGKSNETVAIVQANDNDVDVKNQKLQYHLL--NYHDFF 783 Query: 413 SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENA 472 + + G+ P+ +++ + V+ + + +T ++ A V N+ Sbjct: 784 QLDKETGKVTTIQDVPMTWQRLNISISAVNMDSERFLQSKTFLLVTVTSSSKLA-VQLNS 842 Query: 473 PYTASVFEDAPIGTTV 488 +F++ IG V Sbjct: 843 GNLIRIFKNDKIGEKV 858 >UniRef50_Q0V9M2 Cluster: Putative uncharacterized protein MGC146652; n=1; Xenopus tropicalis|Rep: Putative uncharacterized protein MGC146652 - Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) Length = 911 Score = 227 bits (556), Expect = 3e-57 Identities = 179/615 (29%), Positives = 288/615 (46%), Gaps = 33/615 (5%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F +D ++GAL R +DRE + ++ + ++ ++ + I+D NDN P Sbjct: 74 FFVDQKTGALTVRDRIDRESLCGSSLSCLLPLELG--IEKPFELFSVDIEILDVNDNSPS 131 Query: 150 FSEKTYTVSVDEDISVTDNPVI--AKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS- 206 F + + I + NP + A D+DVG N +Y I N S+ +L Sbjct: 132 FLSDNQIIQI---IEIFANPGVRFPLDTAEDSDVGINGINQYK-INPNPFFSLSVKNLKD 187 Query: 207 ----GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLF 262 ++ L K LD E+ + L++ A DGG RS +T + I + DVNDNAP F + Sbjct: 188 GTLIAELVLEKKLDREEKGQHELLLTAFDGGEQPRSGSTLITIIVLDVNDNAPVFDQPSY 247 Query: 263 QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322 + ++ EN+P+ ++++ A D DEGVNAE++Y T + ++P +G +Y G Sbjct: 248 KITLHENLPLTTVVMKLNATDLDEGVNAEISYLFDHHTSTAAKGI-FGLNPNTGEIYIKG 306 Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382 +D E Y+L V A DGG P + + E+ ED P G Sbjct: 307 FVDFEKTHFYELFVKAVDGGTPRQEGRCLIQVEVEDINDNSPEIIFTSNANEVPEDAPIG 366 Query: 383 TPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 T V +T D D ++ G + F I R + ++ LD ++ +Y + ++ Sbjct: 367 TVVGFITVRDKDSGKNGDVQL-GVSPDLPFKIQPFKNRYSLVTSEHLDREKTPQYTIQLT 425 Query: 443 ATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 A+D G S+ ++ +N++D N+ PVF + Y A + E+ GT + VSATD DVG Sbjct: 426 ASDLGSPALSNQTVILLNVSDVNDNRPVFSQSVYNAHIKENIEPGTLLCTVSATDPDVGS 485 Query: 501 NAQITYSLS-SEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558 N+ +TYS+S S+I +V+ FV IN TG I + D E +T D G Sbjct: 486 NSDLTYSISESQIDGSSVS----SFVFINSNTGDIYAQRSFDYEQFQVLTITARVEDSGS 541 Query: 559 PSLSDTTDVEISVVDVNDNEPVF------KQQLYTANIMEDALVGTSVSQVGATDADVGL 612 P L V I ++D NDN P K + I + A G V+++ A D D G Sbjct: 542 PKLFSNVSVHIFILDTNDNAPSVLYPGDSKGFIAQEKIPQSASAGYLVTKISAIDPDSGH 601 Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKA-LDRESVATHDLKAVAIDGGTPPQSSTV 671 N + Y + + + F I +G IR ++ L+ ++ H + +V+ D G P S+TV Sbjct: 602 NAWLSYRV-VEPIGQTLFEISQYTGEIRIIRSFLEIDNTEQHLVISVS-DHGEPALSATV 659 Query: 672 IVHI-KIEDINDSPP 685 V I +E+I P Sbjct: 660 TVIINSVENIAQELP 674 Score = 196 bits (477), Expect = 1e-47 Identities = 166/572 (29%), Positives = 252/572 (44%), Gaps = 37/572 (6%) Query: 180 DVGANSAI----RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRL-VIRAQDGGS 234 D+G N A R ++ G F +D +G +++ +D E + L + + G Sbjct: 50 DLGLNMADIEKRRLSLRSGANGRYFFVDQKTGALTVRDRIDRESLCGSSLSCLLPLELGI 109 Query: 235 PSRSNTTQLLINIRDVNDNAPRFYT-SLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293 + I I DVNDN+P F + + + + G A D+D G+N Sbjct: 110 EKPFELFSVDIEILDVNDNSPSFLSDNQIIQIIEIFANPGVRFPLDTAEDSDVGINGINQ 169 Query: 294 YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353 Y + + + + +LDRE + +++LL+TA DGG+ PRS + Sbjct: 170 YKINPNPFFSLSVKNLKDGTLIAELVLEKKLDREEKGQHELLLTAFDGGEQPRSGSTLIT 229 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED-----NRLHYEITGGNT 408 F Y++ L E+ P T V+ L ATD DE + L T Sbjct: 230 IIVLDVNDNAPVFDQPSYKITLHENLPLTTVVMKLNATDLDEGVNAEISYLFDHHTSTAA 289 Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYA 466 +G F + G I + +DF++ Y L V A D G + ++Q+ + D N+ + Sbjct: 290 KGIFGLNPNTGE--IYIKGFVDFEKTHFYELFVKAVDGGTPRQEGRCLIQVEVEDINDNS 347 Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 P V EDAPIGT V ++ D D G N + +S ++ F I Sbjct: 348 PEIIFTSNANEVPEDAPIGTVVGFITVRDKDSGKNGDVQLGVSPDLP----------FKI 397 Query: 527 NPQTG--AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584 P ++ T++ LDRE Y + +TA D G P+LS+ T + ++V DVNDN PVF Q Sbjct: 398 QPFKNRYSLVTSEHLDREKTPQYTIQLTASDLGSPALSNQTVILLNVSDVNDNRPVFSQS 457 Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD---REEGSFV-IDPASGVIR 640 +Y A+I E+ GT + V ATD DVG N + Y + SFV I+ +G I Sbjct: 458 VYNAHIKENIEPGTLLCTVSATDPDVGSNSDLTYSISESQIDGSSVSSFVFINSNTGDIY 517 Query: 641 TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP--VFESDCLTFYISE 698 ++ D E + A D G+P S V VHI I D ND+ P ++ D F E Sbjct: 518 AQRSFDYEQFQVLTITARVEDSGSPKLFSNVSVHIFILDTNDNAPSVLYPGDSKGFIAQE 577 Query: 699 NSP----IGTTIGEIRAHDPDEGPNAVVHYSI 726 P G + +I A DPD G NA + Y + Sbjct: 578 KIPQSASAGYLVTKISAIDPDSGHNAWLSYRV 609 Score = 182 bits (444), Expect = 1e-43 Identities = 120/380 (31%), Positives = 191/380 (50%), Gaps = 21/380 (5%) Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480 + + + LD +++ ++ L ++A D G RS + ++ I + D N+ APVF+ Y ++ E Sbjct: 194 LVLEKKLDREEKGQHELLLTAFDGGEQPRSGSTLITIIVLDVNDNAPVFDQPSYKITLHE 253 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 + P+ T V+ ++ATD D G+NA+I+Y S A F +NP TG I +D Sbjct: 254 NLPLTTVVMKLNATDLDEGVNAEISYLFDHHTSTAAKGI----FGLNPNTGEIYIKGFVD 309 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN---IMEDALVG 597 E Y L V A DGG P +++ V D+NDN P + ++T+N + EDA +G Sbjct: 310 FEKTHFYELFVKAVDGGTPRQEGRCLIQVEVEDINDNSP---EIIFTSNANEVPEDAPIG 366 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG--VIRTNKALDRESVATHDL 655 T V + D D G NG + + P + F I P + T++ LDRE + + Sbjct: 367 TVVGFITVRDKDSGKNGDVQLGVSP----DLPFKIQPFKNRYSLVTSEHLDREKTPQYTI 422 Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 + A D G+P S+ ++ + + D+ND+ PVF +I EN GT + + A DPD Sbjct: 423 QLTASDLGSPALSNQTVILLNVSDVNDNRPVFSQSVYNAHIKENIEPGTLLCTVSATDPD 482 Query: 716 EGPNAVVHYSIKGGD-DSNSFSLETRQGSDKAELVTMVDLDYESPRKKY--ELVIRAASP 772 G N+ + YSI D +S S S+ ++ DYE + V + SP Sbjct: 483 VGSNSDLTYSISESQIDGSSVSSFVFINSNTGDIYAQRSFDYEQFQVLTITARVEDSGSP 542 Query: 773 PLWNDVRVEILVTDVNDNAP 792 L+++V V I + D NDNAP Sbjct: 543 KLFSNVSVHIFILDTNDNAP 562 Score = 162 bits (394), Expect = 1e-37 Identities = 152/527 (28%), Positives = 232/527 (44%), Gaps = 34/527 (6%) Query: 366 FMPGQYEVELAEDEPPGTPVVT----LTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421 ++ GQ +AE+ PGT V L AD + R +G N GR+ Q G Sbjct: 25 WVSGQLRYSIAEESEPGTLVGNVAQDLGLNMADIEKRRLSLRSGAN--GRYFFVDQK-TG 81 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGRS---DTAMVQINITDANNYAPVFENAPYTASV 478 +TV +D + L+ G + V I I D N+ +P F + + Sbjct: 82 ALTVRDRIDRESLCGSSLSCLLPLELGIEKPFELFSVDIEILDVNDNSPSFLSDNQIIQI 141 Query: 479 FED-APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 E A G + +A DSDVGIN Y ++ N + + + K Sbjct: 142 IEIFANPGVRFPLDTAEDSDVGINGINQYKINP---NPFFSLSVKNLKDGTLIAELVLEK 198 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 LDRE + L +TA DGG S +T + I V+DVNDN PVF Q Y + E+ + Sbjct: 199 KLDREEKGQHELLLTAFDGGEQPRSGSTLITIIVLDVNDNAPVFDQPSYKITLHENLPLT 258 Query: 598 TSVSQVGATDADVGLNGRIHYELD--PKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655 T V ++ ATD D G+N I Y D +G F ++P +G I +D E ++L Sbjct: 259 TVVMKLNATDLDEGVNAEISYLFDHHTSTAAKGIFGLNPNTGEIYIKGFVDFEKTHFYEL 318 Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 A+DGGTP Q ++ +++EDIND+ P + E++PIGT +G I D D Sbjct: 319 FVKAVDGGTPRQEGRCLIQVEVEDINDNSPEIIFTSNANEVPEDAPIGTVVGFITVRDKD 378 Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPRKKYELVIR-AASPP 773 G N V + S + + ++ LVT LD E +P+ +L SP Sbjct: 379 SGKNGDVQLGV-----SPDLPFKIQPFKNRYSLVTSEHLDREKTPQYTIQLTASDLGSPA 433 Query: 774 LWNDVRVEILVTDVNDNAPVMKDFQIIFNNY--KDCFPVGPFGRVPAYDADV--TDKLQY 829 L N + + V+DVNDN PV Q ++N + ++ P V A D DV L Y Sbjct: 434 LSNQTVILLNVSDVNDNRPVFS--QSVYNAHIKENIEPGTLLCTVSATDPDVGSNSDLTY 491 Query: 830 RI----LSGNN-ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 I + G++ ++ + +N TG + + ++ T+ V D Sbjct: 492 SISESQIDGSSVSSFVFINSNTGDIYAQRSFDYEQFQVLTITARVED 538 Score = 160 bits (389), Expect = 4e-37 Identities = 131/493 (26%), Positives = 214/493 (43%), Gaps = 37/493 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I VLD ND++PVF+ Y+ ++ E T V+ L ATD D G NAE+ Y + T+ Sbjct: 230 IIVLDVNDNAPVFDQPSYKITLHENLPLTTVVMKLNATDLDEGVNAEISYLFDHHTS--- 286 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + +F ++ +G + + +D EK Y + VKA D +P R Sbjct: 287 -------------TAAKGIFGLNPNTGEIYIKGFVDFEKTHFYELFVKAVDGGTP---RQ 330 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 I V + D NDN P+ + V ED + V+ I D D G N ++ Sbjct: 331 EGRCLIQVEVEDINDNSPEIIFTSNANEVPEDAPI--GTVVGFITVRDKDSGKNGDVQ-- 386 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 +G + + F I SLV + LD E+ Y + + A D GSP+ SN T +L+N+ Sbjct: 387 -LGVSPDLPFKIQPFKNRYSLVTSEHLDREKTPQYTIQLTASDLGSPALSNQTVILLNVS 445 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NVDL 307 DVNDN P F S++ + EN+ G + V A D D G N++LTY++++ G +V Sbjct: 446 DVNDNRPVFSQSVYNAHIKENIEPGTLLCTVSATDPDVGSNSDLTYSISESQIDGSSVSS 505 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR-SATATXXXXXXXXXXXXXXF 366 + I+ +G +Y D E + D G P S + Sbjct: 506 FVFINSNTGDIYAQRSFDYEQFQVLTITARVEDSGSPKLFSNVSVHIFILDTNDNAPSVL 565 Query: 367 MPGQYEVELAEDEPP-----GTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNG 419 PG + +A+++ P G V ++A D D + L Y + + F I+ G Sbjct: 566 YPGDSKGFIAQEKIPQSASAGYLVTKISAIDPDSGHNAWLSYRVVEPIGQTLFEISQYTG 625 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479 + + L+ ++ L +S +D G + +A V + I N A ++ Sbjct: 626 E-IRIIRSFLEIDNTEQH-LVISVSDHGEPALSATVTVIINSVENIAQELPHSQDMIPHS 683 Query: 480 EDAPIGTTVLVVS 492 + +P T L++S Sbjct: 684 QTSPNLTLYLIIS 696 Score = 105 bits (253), Expect = 1e-20 Identities = 73/277 (26%), Positives = 125/277 (45%), Gaps = 25/277 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +NV D ND+ PVF Y A ++E GT + T+ ATD D+G N+++ Y+I D Sbjct: 442 LNVSDVNDNRPVFSQSVYNAHIKENIEPGTLLCTVSATDPDVGSNSDLTYSISESQID-- 499 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 V I+ +G + + S D E+ T+ + D SP +L Sbjct: 500 ------------GSSVSSFVFINSNTGDIYAQRSFDYEQFQVLTITARVEDSGSP---KL 544 Query: 131 SSTATIHVNIIDDNDNYPQF----SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 S ++H+ I+D NDN P K + S + ++ KI A D D G N+ Sbjct: 545 FSNVSVHIFILDTNDNAPSVLYPGDSKGFIAQEKIPQSASAGYLVTKISAIDPDSGHNAW 604 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 + Y ++ Q F I +G++ ++++ L+ + + LVI D G P+ S T ++I Sbjct: 605 LSYRVVEPIGQTLFEISQYTGEIRIIRSFLEIDNTEQH-LVISVSDHGEPALSATVTVII 663 Query: 246 N-IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA 281 N + ++ P + S N+ + Y I+ + A Sbjct: 664 NSVENIAQELPHSQDMIPHSQTSPNLTL-YLIISLVA 699 >UniRef50_UPI0000E821D2 Cluster: PREDICTED: similar to protocadherin gamma B5, partial; n=2; Gallus gallus|Rep: PREDICTED: similar to protocadherin gamma B5, partial - Gallus gallus Length = 850 Score = 227 bits (555), Expect = 3e-57 Identities = 160/564 (28%), Positives = 263/564 (46%), Gaps = 28/564 (4%) Query: 197 QMQFSIDSLSGDVSLVKTLDYEQV-RSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP 255 ++ F++ +G++ + + LD E++ R + + + N + + I D+NDN+P Sbjct: 74 KLYFAVSGENGNLYVSERLDREELCRESESCAVSFEAVVQNPLNVFHVEVAIHDINDNSP 133 Query: 256 RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315 F ++ + E G A D D G N+ LTY +T+ D + ++ + ++ + Sbjct: 134 AFSKAVLDLEIGEWTIPGARFPLEVAQDPDVGSNSLLTYQLTE-DSSFSLAMKVSKGGKQ 192 Query: 316 G-WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374 + LDRE Q+ +Q+++TATDGGD +S + F Y+ + Sbjct: 193 QPELVLERALDREKQSSFQMVLTATDGGDSAKSGSVHIRVNVSDANDNAPVFNKNAYDAQ 252 Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT----RGRFSITSQNGRGLITVAQPLD 430 + E+ P G+ V+ + A DAD + GN R FSI +++G + A PLD Sbjct: 253 MRENLPVGSLVLQVRAADADAGSNGRVSYFFGNVPESVRSLFSIDAESGE--VRTAGPLD 310 Query: 431 FKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 F++ +Y + D GG + VQI+I D N+ AP ++ V EDAP GT V + Sbjct: 311 FEERSKYSFGLEGRDGGGLTGHCEVQIDIIDENDNAPEITTLSLSSRVPEDAPPGTVVAL 370 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550 + D D G N Q+ LS + + VA + + T LDRE S + +T Sbjct: 371 LKVRDRDSGENGQVRCELSGDTPLQIVASSGGSY-------KVVTAGALDRERASEHRVT 423 Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610 V A D G P+LS D+ + V DVNDN PVF++ Y+A + E+ G V +V A DAD Sbjct: 424 VIATDRGSPALSSRADLVLEVSDVNDNAPVFEEAAYSAYVPENNAAGEPVLRVSARDADA 483 Query: 611 GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST 670 G NGR+ Y L + + +G + ++ D E ++ A DGGTP +S+T Sbjct: 484 GANGRVSYALAGGGADAAFVSVRAETGELYAQRSFDYERCREFSVEVRARDGGTPARSAT 543 Query: 671 VIVHIKIEDINDSPPVF-----------ESDCLTF-YISENSPIGTTIGEIRAHDPDEGP 718 V + + D ND+ P + F + ++ G + ++ A D D G Sbjct: 544 ATVRVFVLDRNDNAPRVLWPAAGGAEGGGAGAGPFEVVPRSAEAGYLVAKVVAVDADAGR 603 Query: 719 NAVVHYSIKGGDDSNSFSLETRQG 742 NA + Y + + F +E R G Sbjct: 604 NAWLSYELLQAPEPALFRVEARSG 627 Score = 225 bits (549), Expect = 2e-56 Identities = 184/618 (29%), Positives = 287/618 (46%), Gaps = 46/618 (7%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F + G +G L LDRE++ R + + +A V + + V I D NDN P Sbjct: 77 FAVSGENGNLYVSERLDREELCRESESCAVSFEA--VVQNPLNVFHVEVAIHDINDNSPA 134 Query: 150 FSEKTYTVSVDE-DISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG- 207 FS+ + + E I P+ A D DVG+NS + Y + ++ S G Sbjct: 135 FSKAVLDLEIGEWTIPGARFPLEV---AQDPDVGSNSLLTYQLTEDSSFSLAMKVSKGGK 191 Query: 208 ---DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 ++ L + LD E+ S+++V+ A DGG ++S + + +N+ D NDNAP F + + Sbjct: 192 QQPELVLERALDREKQSSFQMVLTATDGGDSAKSGSVHIRVNVSDANDNAPVFNKNAYDA 251 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 + EN+P+G +++V+A DAD G N ++Y + +V +ID SG V T+G L Sbjct: 252 QMRENLPVGSLVLQVRAADADAGSNGRVSYFF--GNVPESVRSLFSIDAESGEVRTAGPL 309 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 D E ++KY + DGG + + ED PPGT Sbjct: 310 DFEERSKYSFGLEGRDGGGLTGHCEVQIDIIDENDNAPEITTL--SLSSRVPEDAPPGTV 367 Query: 385 VVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 V L D D E+ ++ E++G + S G + A LD ++ + +TV Sbjct: 368 VALLKVRDRDSGENGQVRCELSGDTPLQ--IVASSGGSYKVVTAGALDRERASEHRVTVI 425 Query: 443 ATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 ATD G S A + + ++D N+ APVFE A Y+A V E+ G VL VSA D+D G Sbjct: 426 ATDRGSPALSSRADLVLEVSDVNDNAPVFEEAAYSAYVPENNAAGEPVLRVSARDADAGA 485 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560 N +++Y+L+ ++ A + +TG + + D E + + V ARDGG P+ Sbjct: 486 NGRVSYALAGGGADAAFVS------VRAETGELYAQRSFDYERCREFSVEVRARDGGTPA 539 Query: 561 LSDTTDVEISVVDVNDNEP-VFKQQLYTAN-----------IMEDALVGTSVSQVGATDA 608 S T V + V+D NDN P V A + A G V++V A DA Sbjct: 540 RSATATVRVFVLDRNDNAPRVLWPAAGGAEGGGAGAGPFEVVPRSAEAGYLVAKVVAVDA 599 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 D G N + YEL + E F ++ SG +RT +A + H L A G P S Sbjct: 600 DAGRNAWLSYEL-LQAPEPALFRVEARSGEVRTARA---KKQRPHPL---ATGHGQPALS 652 Query: 669 STVIVHIKI-EDINDSPP 685 +T +H+ + E + D+ P Sbjct: 653 ATATLHVVLAESVRDALP 670 Score = 192 bits (467), Expect = 2e-46 Identities = 131/436 (30%), Positives = 216/436 (49%), Gaps = 21/436 (4%) Query: 366 FMPGQYEVELAEDEPPGT--PVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL- 422 F ++E+ E PG P+ D ++ L Y++T ++ S+ G+ Sbjct: 135 FSKAVLDLEIGEWTIPGARFPLEVAQDPDVGSNSLLTYQLTEDSSFSLAMKVSKGGKQQP 194 Query: 423 -ITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVF 479 + + + LD +++ + + ++ATD G +S + +++N++DAN+ APVF Y A + Sbjct: 195 ELVLERALDREKQSSFQMVLTATDGGDSAKSGSVHIRVNVSDANDNAPVFNKNAYDAQMR 254 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E+ P+G+ VL V A D+D G N +++Y + E+V F I+ ++G + T L Sbjct: 255 ENLPVGSLVLQVRAADADAGSNGRVSYFFGNV--PESVR---SLFSIDAESGEVRTAGPL 309 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 D E S Y + RDGG L+ +V+I ++D NDN P ++ + EDA GT Sbjct: 310 DFEERSKYSFGLEGRDGG--GLTGHCEVQIDIIDENDNAPEITTLSLSSRVPEDAPPGTV 367 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 V+ + D D G NG++ EL D S + T ALDRE + H + +A Sbjct: 368 VALLKVRDRDSGENGQVRCELSG-DTPLQIVASSGGSYKVVTAGALDRERASEHRVTVIA 426 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 D G+P SS + +++ D+ND+ PVFE + Y+ EN+ G + + A D D G N Sbjct: 427 TDRGSPALSSRADLVLEVSDVNDNAPVFEEAAYSAYVPENNAAGEPVLRVSARDADAGAN 486 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776 V Y++ GG +F + R ++ EL DYE R ++ + +RA +P Sbjct: 487 GRVSYALAGGGADAAF-VSVR--AETGELYAQRSFDYERCR-EFSVEVRARDGGTPARSA 542 Query: 777 DVRVEILVTDVNDNAP 792 V + V D NDNAP Sbjct: 543 TATVRVFVLDRNDNAP 558 Score = 181 bits (440), Expect = 3e-43 Identities = 146/523 (27%), Positives = 234/523 (44%), Gaps = 53/523 (10%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 H ++ + D ND+SP F + + E G A D D+G N+ + Y + Sbjct: 120 HVEVAIHDINDNSPAFSKAVLDLEIGEWTIPGARFPLEVAQDPDVGSNSLLTYQLT---- 175 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 ED+ V + + L+ +LDREK + + +++ ATD Sbjct: 176 -----EDSSFSLA------MKVSKGGKQQPELVLERALDREKQSSFQMVLTATDGGDSAK 224 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 S + I VN+ D NDN P F++ Y + E++ V ++ +++A DAD G+N + Sbjct: 225 ---SGSVHIRVNVSDANDNAPVFNKNAYDAQMRENLPV--GSLVLQVRAADADAGSNGRV 279 Query: 188 RYAI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 Y + + + FSID+ SG+V LD+E+ Y + +DGG + ++ I Sbjct: 280 SYFFGNVPESVRSLFSIDAESGEVRTAGPLDFEERSKYSFGLEGRDGG--GLTGHCEVQI 337 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 +I D NDNAP T V E+ P G + ++ D D G N ++ ++ Sbjct: 338 DIIDENDNAPEITTLSLSSRVPEDAPPGTVVALLKVRDRDSGENGQVRCELSG------- 390 Query: 306 DLPITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 D P+ I SG Y T+G LDRE +++++ V ATD G P S+ A Sbjct: 391 DTPLQIVASSGGSYKVVTAGALDRERASEHRVTVIATDRGSPALSSRADLVLEVSDVNDN 450 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRF-SITSQNG 419 F Y + E+ G PV+ ++A DAD + R+ Y + GG F S+ ++ G Sbjct: 451 APVFEEAAYSAYVPENNAAGEPVLRVSARDADAGANGRVSYALAGGGADAAFVSVRAETG 510 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVF-------- 469 + + D+++ R + + V A D G RS TA V++ + D N+ AP Sbjct: 511 E--LYAQRSFDYERCREFSVEVRARDGGTPARSATATVRVFVLDRNDNAPRVLWPAAGGA 568 Query: 470 ENAPYTASVFEDAP----IGTTVLVVSATDSDVGINAQITYSL 508 E A FE P G V V A D+D G NA ++Y L Sbjct: 569 EGGGAGAGPFEVVPRSAEAGYLVAKVVAVDADAGRNAWLSYEL 611 Score = 171 bits (417), Expect = 2e-40 Identities = 113/348 (32%), Positives = 173/348 (49%), Gaps = 33/348 (9%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 +H ++NV D ND++PVF Y+A +RE G+ VL ++A D D G N V Y V Sbjct: 228 VHIRVNVSDANDNAPVFNKNAYDAQMRENLPVGSLVLQVRAADADAGSNGRVSYFFGNV- 286 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 PE V+ +F ID SG + T LD E+ ++Y+ ++ D Sbjct: 287 -----PE-----------SVRSLFSIDAESGEVRTAGPLDFEERSKYSFGLEGRDGGG-- 328 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 L+ + ++IID+NDN P+ + + + V ED V+A +K D D G N Sbjct: 329 ---LTGHCEVQIDIIDENDNAPEITTLSLSSRVPED--APPGTVVALLKVRDRDSGENGQ 383 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVK--TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 +R + G+T +Q + S G +V LD E+ +R+ + A D GSP+ S+ L+ Sbjct: 384 VR-CELSGDTPLQI-VASSGGSYKVVTAGALDRERASEHRVTVIATDRGSPALSSRADLV 441 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + + DVNDNAP F + + V EN G ++RV A DAD G N ++Y + G Sbjct: 442 LEVSDVNDNAPVFEEAAYSAYVPENNAAGEPVLRVSARDADAGANGRVSYALAG----GG 497 Query: 305 VDLP-ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 D +++ +G +Y D E ++ + V A DGG P RSATAT Sbjct: 498 ADAAFVSVRAETGELYAQRSFDYERCREFSVEVRARDGGTPARSATAT 545 Score = 159 bits (385), Expect = 1e-36 Identities = 121/422 (28%), Positives = 190/422 (45%), Gaps = 11/422 (2%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 V++ I D N+ +P F A + E G + A D DVG N+ +TY L+ + S Sbjct: 121 VEVAIHDINDNSPAFSKAVLDLEIGEWTIPGARFPLEVAQDPDVGSNSLLTYQLTEDSSF 180 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 + P+ + + LDRE S + + +TA DGG + S + + ++V D Sbjct: 181 SLAMKVSKGGKQQPE---LVLERALDREKQSSFQMVLTATDGGDSAKSGSVHIRVNVSDA 237 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFVID 633 NDN PVF + Y A + E+ VG+ V QV A DAD G NGR+ Y + + F ID Sbjct: 238 NDNAPVFNKNAYDAQMRENLPVGSLVLQVRAADADAGSNGRVSYFFGNVPESVRSLFSID 297 Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693 SG +RT LD E + + DGG + V I I D ND+ P + L+ Sbjct: 298 AESGEVRTAGPLDFEERSKYSFGLEGRDGGG--LTGHCEVQIDIIDENDNAPEITTLSLS 355 Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753 + E++P GT + ++ D D G N V + G D+ + + GS K +D Sbjct: 356 SRVPEDAPPGTVVALLKVRDRDSGENGQVRCELSG--DTPLQIVASSGGSYKVVTAGALD 413 Query: 754 LDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF 813 + S + + SP L + + + V+DVNDNAPV ++ ++ P Sbjct: 414 RERASEHRVTVIATDRGSPALSSRADLVLEVSDVNDNAPVFEEAAYSAYVPENNAAGEPV 473 Query: 814 GRVPAYDAD--VTDKLQYRILSGN-NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVT 870 RV A DAD ++ Y + G +A + + TG + + + ++EV Sbjct: 474 LRVSARDADAGANGRVSYALAGGGADAAFVSVRAETGELYAQRSFDYERCREFSVEVRAR 533 Query: 871 DG 872 DG Sbjct: 534 DG 535 Score = 65.3 bits (152), Expect = 2e-08 Identities = 65/242 (26%), Positives = 103/242 (42%), Gaps = 10/242 (4%) Query: 601 SQVGATDADVGLN-GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK-AV 658 S VG D+GL+ + E+ F + +G + ++ LDRE + AV Sbjct: 47 SLVGPLARDLGLSPAELPARQLRLSSEKLYFAVSGENGNLYVSERLDREELCRESESCAV 106 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 + + + V + I DIND+ P F L I E + G A DPD G Sbjct: 107 SFEAVVQNPLNVFHVEVAIHDINDNSPAFSKAVLDLEIGEWTIPGARFPLEVAQDPDVGS 166 Query: 719 NAVVHYSIKGGDDSNSFSLE-TRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPL 774 N+++ Y + D S S +++ ++ G + ELV LD E + +++V+ A Sbjct: 167 NSLLTYQLT-EDSSFSLAMKVSKGGKQQPELVLERALDREK-QSSFQMVLTATDGGDSAK 224 Query: 775 WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVTDKLQYRILS 833 V + + V+D NDNAPV ++ PVG +V A DAD + Sbjct: 225 SGSVHIRVNVSDANDNAPVFNK-NAYDAQMRENLPVGSLVLQVRAADADAGSNGRVSYFF 283 Query: 834 GN 835 GN Sbjct: 284 GN 285 >UniRef50_A4KCM6 Cluster: Protocadherin 2G25; n=4; Takifugu rubripes|Rep: Protocadherin 2G25 - Fugu rubripes (Japanese pufferfish) (Takifugu rubripes) Length = 950 Score = 227 bits (555), Expect = 3e-57 Identities = 154/510 (30%), Positives = 241/510 (47%), Gaps = 21/510 (4%) Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + I D+NDN P F + +SE+ G V +A D D G+N+ +YT+ D Sbjct: 123 VEITDINDNPPTFERDEIRYDISESALTGARFVLEKAIDDDVGLNSLKSYTLKPSDNFVL 182 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 + + + QLDRE Q L++TA DGG+P S T Sbjct: 183 KTVNRGDGSKHVEMVLQKQLDRENQNHVSLILTALDGGEPQLSGTMQIIVTVLDANDNPP 242 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGL 422 +Y+ + E+ P GT + T++ATD DE N + Y I+ G F I + +G + Sbjct: 243 VCSKPEYKASVRENAPIGTRITTVSATDKDEGNNGIVTYMISKSGAAGLFRIDATDG--V 300 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 +T++ +D+++ + Y L V +D GG SD V +++TD N+ P + +V E+ Sbjct: 301 LTLSGNVDYEKRKHYELDVQVSDQGGLSDACRVTVDVTDTNDNPPSINIMSKSQTVSENT 360 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 GT + +++ D D N ++ L I H + N IT ++L DRE Sbjct: 361 KPGTVITMLNVQDPDSNENGRVMCVLDENI------HFTIRSTTNNFFTVITDSEL-DRE 413 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 S Y +TV+ D GVPSLS + + + + DVNDN PVF++ Y A I+E+ G SV Sbjct: 414 RESEYNITVSCSDEGVPSLSSSVTLTLQISDVNDNPPVFERSSYEAYIVENNTPGLSVFT 473 Query: 603 VGATDADVGLNGRIHYELDPKDRE---EGSFV-IDPASGVIRTNKALDRESVATHDLKAV 658 V A DAD N R+ Y L+ S+V + SGV+ ++ D E + Sbjct: 474 VKARDADWNQNARVSYILEDSSVNGVPVSSYVSVSADSGVVHAVRSFDYEQIKDFHFLVK 533 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVF------ESDCLTFYISENSPIGTTIGEIRAH 712 A DGG+PP SS V V I I+D ND+PP + + ++ +G + ++ A Sbjct: 534 AQDGGSPPLSSNVSVKILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAV 593 Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 D D G NA + Y ++ D F + + G Sbjct: 594 DVDSGQNAWLSYKLQKATDRALFEVGLQNG 623 Score = 221 bits (541), Expect = 2e-55 Identities = 174/597 (29%), Positives = 268/597 (44%), Gaps = 29/597 (4%) Query: 97 GALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT 156 G LL + +DRE + T+ Q + + T+ V I D NDN P F Sbjct: 84 GVLLIKDRIDREALCGQTMPCALHFQM--ILENPMEFYTVTVEITDINDNPPTFERDEIR 141 Query: 157 VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG----DVSLV 212 + E ++T + + KA D DVG NS Y + + + +++ G ++ L Sbjct: 142 YDISES-ALTGARFVLE-KAIDDDVGLNSLKSYTLKPSDNFVLKTVNRGDGSKHVEMVLQ 199 Query: 213 KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI 272 K LD E L++ A DGG P S T Q+++ + D NDN P ++ SV EN PI Sbjct: 200 KQLDRENQNHVSLILTALDGGEPQLSGTMQIIVTVLDANDNPPVCSKPEYKASVRENAPI 259 Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332 G I V A D DEG N +TY ++ G ID G + SG +D E + Y Sbjct: 260 GTRITTVSATDKDEGNNGIVTYMISKSGAAG----LFRIDATDGVLTLSGNVDYEKRKHY 315 Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392 +L V +D G + T M V +E+ PGT + L D Sbjct: 316 ELDVQVSDQGGLSDACRVTVDVTDTNDNPPSINIMSKSQTV--SENTKPGTVITMLNVQD 373 Query: 393 AD-EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GR 449 D +N + N T+ N +IT ++ LD ++E Y +TVS +D G Sbjct: 374 PDSNENGRVMCVLDENIHFTIRSTTNNFFTVITDSE-LDRERESEYNITVSCSDEGVPSL 432 Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL- 508 S + + + I+D N+ PVFE + Y A + E+ G +V V A D+D NA+++Y L Sbjct: 433 SSSVTLTLQISDVNDNPPVFERSSYEAYIVENNTPGLSVFTVKARDADWNQNARVSYILE 492 Query: 509 SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568 S ++ V+ + ++ +G + + D E + + V A+DGG P LS V+ Sbjct: 493 DSSVNGVPVSSY---VSVSADSGVVHAVRSFDYEQIKDFHFLVKAQDGGSPPLSSNVSVK 549 Query: 569 ISVVDVNDNEPVFKQQLYTANIM------EDALVGTSVSQVGATDADVGLNGRIHYELDP 622 I + D NDN P + T M A VG V++V A D D G N + Y+L Sbjct: 550 ILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLQ- 608 Query: 623 KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679 K + F + +G IRT + + + L + D G P +S+TVIV++ + D Sbjct: 609 KATDRALFEVGLQNGEIRTIRQVTDKDAVKQRLSVIVEDNGQPSRSATVIVNVAVAD 665 Score = 184 bits (449), Expect = 2e-44 Identities = 157/578 (27%), Positives = 249/578 (43%), Gaps = 50/578 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND+ P FE + + E A +G + KA D D+G N+ Y TL Sbjct: 123 VEITDINDNPPTFERDEIRYDISESALTGARFVLEKAIDDDVGLNSLKSY--------TL 174 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 P D ++ V R DG + ++ + LDRE ++++ A D P + Sbjct: 175 KPSD--------NFVLKTVNRGDGSKHVEMVLQKQLDRENQNHVSLILTALDGGEP---Q 223 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LS T I V ++D NDN P S+ Y SV E+ + I + ATD D G N + Y Sbjct: 224 LSGTMQIIVTVLDANDNPPVCSKPEYKASVRENAPIGTR--ITTVSATDKDEGNNGIVTY 281 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I F ID+ G ++L +DYE+ + Y L ++ D G S+ ++ +++ D Sbjct: 282 MISKSGAAGLFRIDATDGVLTLSGNVDYEKRKHYELDVQVSDQG--GLSDACRVTVDVTD 339 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 NDN P ++VSEN G I + D D N + + + N+ I Sbjct: 340 TNDNPPSINIMSKSQTVSENTKPGTVITMLNVQDPDSNENGRVMCVLDE-----NIHFTI 394 Query: 310 TIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 + + V T +LDRE +++Y + V+ +D G P S++ T F Sbjct: 395 RSTTNNFFTVITDSELDRERESEYNITVSCSDEGVPSLSSSVTLTLQISDVNDNPPVFER 454 Query: 369 GQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRG---RFSITSQNGRGLI 423 YE + E+ PG V T+ A DAD ++ R+ Y + + G ++ G++ Sbjct: 455 SSYEAYIVENNTPGLSVFTVKARDADWNQNARVSYILEDSSVNGVPVSSYVSVSADSGVV 514 Query: 424 TVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTAS---- 477 + D++Q + + V A D G S V+I I D N+ P T Sbjct: 515 HAVRSFDYEQIKDFHFLVKAQDGGSPPLSSNVSVKILIQDQNDNPPQVLYPVQTGGSMVA 574 Query: 478 --VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 V A +G V V A D D G NA ++Y L + ++ A+ F + Q G I T Sbjct: 575 EMVPRSADVGYLVTKVVAVDVDSGQNAWLSYKL-QKATDRAL------FEVGLQNGEIRT 627 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 + + + L+V D G PS S T V ++V D Sbjct: 628 IRQVTDKDAVKQRLSVIVEDNGQPSRSATVIVNVAVAD 665 Score = 171 bits (416), Expect = 2e-40 Identities = 122/379 (32%), Positives = 181/379 (47%), Gaps = 23/379 (6%) Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFE 480 + + + LD + + L ++A D G S T + + + DAN+ PV Y ASV E Sbjct: 196 MVLQKQLDRENQNHVSLILTALDGGEPQLSGTMQIIVTVLDANDNPPVCSKPEYKASVRE 255 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 +APIGT + VSATD D G N +TY +S S A F I+ G +T + +D Sbjct: 256 NAPIGTRITTVSATDKDEGNNGIVTYMISK--SGAAGL-----FRIDATDGVLTLSGNVD 308 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 E Y L V D G LSD V + V D NDN P + + E+ GT + Sbjct: 309 YEKRKHYELDVQVSDQG--GLSDACRVTVDVTDTNDNPPSINIMSKSQTVSENTKPGTVI 366 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG---VIRTNKALDRESVATHDLKA 657 + + D D NGR+ LD E F I + + T+ LDRE + +++ Sbjct: 367 TMLNVQDPDSNENGRVMCVLD----ENIHFTIRSTTNNFFTVITDSELDRERESEYNITV 422 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 D G P SS+V + ++I D+ND+PPVFE YI EN+ G ++ ++A D D Sbjct: 423 SCSDEGVPSLSSSVTLTLQISDVNDNPPVFERSSYEAYIVENNTPGLSVFTVKARDADWN 482 Query: 718 PNAVVHYSIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPP 773 NA V Y ++ + S +D + + DYE K + +++A SPP Sbjct: 483 QNARVSYILEDSSVNGVPVSSYVSVSADSGVVHAVRSFDYEQI-KDFHFLVKAQDGGSPP 541 Query: 774 LWNDVRVEILVTDVNDNAP 792 L ++V V+IL+ D NDN P Sbjct: 542 LSSNVSVKILIQDQNDNPP 560 Score = 165 bits (402), Expect = 1e-38 Identities = 138/470 (29%), Positives = 205/470 (43%), Gaps = 43/470 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND+ PV +Y+ASVRE A GT + T+ ATD+D G N V Y I A L Sbjct: 232 VTVLDANDNPPVCSKPEYKASVRENAPIGTRITTVSATDKDEGNNGIVTYMISKSGAAGL 291 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 FRID G L ++D EK Y + V+ +DQ L Sbjct: 292 -------------------FRIDATDGVLTLSGNVDYEKRKHYELDVQVSDQGG-----L 327 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S + V++ D NDN P + + + +V E + VI + D D N + Sbjct: 328 SDACRVTVDVTDTNDNPPSINIMSKSQTVSE--NTKPGTVITMLNVQDPDSNENGRVMCV 385 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 + + + F+I S + + V T LD E+ Y + + D G PS S++ L + I Sbjct: 386 L---DENIHFTIRSTTNNFFTVITDSELDRERESEYNITVSCSDEGVPSLSSSVTLTLQI 442 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NVD 306 DVNDN P F S ++ + EN G S+ V+A DAD NA ++Y + D G V Sbjct: 443 SDVNDNPPVFERSSYEAYIVENNTPGLSVFTVKARDADWNQNARVSYILEDSSVNGVPVS 502 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 +++ SG V+ D E + LV A DGG PP S+ + Sbjct: 503 SYVSVSADSGVVHAVRSFDYEQIKDFHFLVKAQDGGSPPLSSNVSVKILIQDQNDNPPQV 562 Query: 367 M-PGQYEVELAEDEPP-----GTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQN 418 + P Q + + P G V + A D D L Y++ R F + QN Sbjct: 563 LYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLQKATDRALFEVGLQN 622 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468 G + T+ Q D K + L+V D+G S +A V +N+ A+++ V Sbjct: 623 GE-IRTIRQVTD-KDAVKQRLSVIVEDNGQPSRSATVIVNVAVADSFPEV 670 Score = 150 bits (364), Expect = 5e-34 Identities = 106/346 (30%), Positives = 166/346 (47%), Gaps = 18/346 (5%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL--SSEI 512 V + ITD N+ P FE + E A G ++ A D DVG+N+ +Y+L S Sbjct: 121 VTVEITDINDNPPTFERDEIRYDISESALTGARFVLEKAIDDDVGLNSLKSYTLKPSDNF 180 Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572 + V D + + K LDRE + L +TA DGG P LS T + ++V+ Sbjct: 181 VLKTVNRGDGSKHVE-----MVLQKQLDRENQNHVSLILTALDGGEPQLSGTMQIIVTVL 235 Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632 D NDN PV + Y A++ E+A +GT ++ V ATD D G NG + Y + K G F I Sbjct: 236 DANDNPPVCSKPEYKASVRENAPIGTRITTVSATDKDEGNNGIVTYMIS-KSGAAGLFRI 294 Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692 D GV+ + +D E ++L D G S V + + D ND+PP Sbjct: 295 DATDGVLTLSGNVDYEKRKHYELDVQVSDQGG--LSDACRVTVDVTDTNDNPPSINIMSK 352 Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752 + +SEN+ GT I + DPD N V + D++ F++ + ++ ++T Sbjct: 353 SQTVSENTKPGTVITMLNVQDPDSNENGRVMCVL---DENIHFTIRSTT-NNFFTVITDS 408 Query: 753 DLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMK 795 +LD E +Y + + + P L + V + + ++DVNDN PV + Sbjct: 409 ELDRER-ESEYNITVSCSDEGVPSLSSSVTLTLQISDVNDNPPVFE 453 Score = 78.6 bits (185), Expect = 2e-12 Identities = 60/205 (29%), Positives = 99/205 (48%), Gaps = 8/205 (3%) Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732 V ++I DIND+PP FE D + + ISE++ G +A D D G N++ Y++K D+ Sbjct: 121 VTVEITDINDNPPTFERDEIRYDISESALTGARFVLEKAIDDDVGLNSLKSYTLKPSDNF 180 Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVND 789 ++ GS E+V LD E+ + L++ A P L +++ + V D ND Sbjct: 181 VLKTVNRGDGSKHVEMVLQKQLDREN-QNHVSLILTALDGGEPQLSGTMQIIVTVLDAND 239 Query: 790 NAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADVTDK--LQYRILSGNNANLILLNETT 846 N PV + + ++ P+G V A D D + + Y I A L ++ T Sbjct: 240 NPPVCSKPE-YKASVRENAPIGTRITTVSATDKDEGNNGIVTYMISKSGAAGLFRIDATD 298 Query: 847 GSMTLSPQLNTNVPKLATMEVSVTD 871 G +TLS ++ K ++V V+D Sbjct: 299 GVLTLSGNVDYEKRKHYELDVQVSD 323 >UniRef50_UPI0000F1FBA8 Cluster: PREDICTED: hypothetical protein; n=2; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 841 Score = 226 bits (553), Expect = 6e-57 Identities = 194/715 (27%), Positives = 321/715 (44%), Gaps = 31/715 (4%) Query: 91 RIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQF 150 R+D +G L T+ LDRE + + T + V + + + D NDN P F Sbjct: 65 RVDEITGDLFTKDRLDRETLCPSHQDGECTFLNTAVVSPHLDVVPMVIVVNDINDNAPVF 124 Query: 151 SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVS 210 + + ED S+ + +A D D N I Y + G N + ++ Sbjct: 125 ERNEIPLRIPEDTSI-GTTFLLDDQAQDKDTANNGLIHYHLEGSNGFFGIRQEDYGLELI 183 Query: 211 LVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENV 270 + K LD E +Y LV+ A D GS S T L + + DV+DN P F +++ + Sbjct: 184 VQKELDRETQDNYFLVLVAVDRGSMPLSATANLSVTVTDVDDNCPEFDDDSPIKAIVPGL 243 Query: 271 PI-GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329 I G ++ +++A D D G NA++T++ + + + +D +G + + + ++ Sbjct: 244 GIKGTAVAQLKATDKDLGQNAQITFSFS-RQISDRAKTLFYMDRHTGLISLAVDVHTDSP 302 Query: 330 AKYQLLVTATDGGDPPRSATATXXX--XXXXXXXXXXXFMPGQYE--VELAEDEPPGTPV 385 ++ L V A PP A T F+ + L E+EPP T + Sbjct: 303 EEHMLKVFANGPLCPPAQAQVTVYIQPMVSSEPTIKIRFVTEHKNQVIMLQENEPP-TVL 361 Query: 386 VTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445 L D D ++ FS+ Q G L++ ++ LDF+ Y +TV +D Sbjct: 362 ALLELEDTSSDKG---TLSLETDSMPFSLKQQAGSYLLSTSKALDFELCGEYDVTVVISD 418 Query: 446 SGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503 G ++++ + D N+ AP FE Y + E+ G +L V ATD+D + Sbjct: 419 PHGARLHGREVIKVVVQDLNDNAPKFEQTRYETDIKENNKPGEFLLKVQATDADSHQFGK 478 Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD 563 + Y ++ + F I +TG I + LDRE Y+LTV A+DGG PS Sbjct: 479 VEYRIT----------NGSPFRIQEETGVILVTEPLDREQQGTYILTVLAQDGGDPSQEA 528 Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK 623 V ++V+D+NDN P F + + E + V +V +DAD G NGRI +D + Sbjct: 529 FAIVFVNVLDMNDNPPAFPTPHFYFFVSESLPHLSQVGKVTVSDADDGDNGRI---VDLR 585 Query: 624 D-REEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND 682 ++ FVID + G++R+ +DRE ++L VA+DGG+P S+TV + + +EDIND Sbjct: 586 ILNDKAPFVIDMSQGMLRSTGEVDREKQDRYELLVVAVDGGSPVLSTTVKMTVFVEDIND 645 Query: 683 SPP---VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLET 739 + P + S+ IS + G+ I +I A D D G N+ + Y I + + + Sbjct: 646 NQPQVLLPSSNLSCLTISPATQAGSMITKIYAIDEDSGMNSDITYQIIASEPALQSPFQI 705 Query: 740 RQGSDKAELVTMVDLDYESPRKKYELVIRAASP-PLWNDVRVEILVTDVNDNAPV 793 Q S LV + + + +V P PL + V +LV + + V Sbjct: 706 DQHSGNITLVQHLRGEDYGMHHLFIVVRDGGKPDPLQTTIWVNLLVNETLEKCHV 760 Score = 189 bits (461), Expect = 8e-46 Identities = 183/687 (26%), Positives = 304/687 (44%), Gaps = 63/687 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTT-VLTLKATDQDIGKNAEVEYTIELVTADT 69 I V D ND++PVFE + + E S GTT +L +A D+D N + Y +E Sbjct: 112 IVVNDINDNAPVFERNEIPLRIPEDTSIGTTFLLDDQAQDKDTANNGLIHYHLE------ 165 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 Q+ + ++ L+ + LDRE Y +++ A D+ S Sbjct: 166 --------GSNGFFGIRQEDYGLE-----LIVQKELDRETQDNYFLVLVAVDRGSM---P 209 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LS+TA + V + D +DN P+F + + ++ + + +A++KATD D+G N+ I + Sbjct: 210 LSATANLSVTVTDVDDNCPEFDDDSPIKAIVPGLGI-KGTAVAQLKATDKDLGQNAQITF 268 Query: 190 AI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 + I + F +D +G +SL + + + L + A P Q+ + Sbjct: 269 SFSRQISDRAKTLFYMDRHTGLISLAVDVHTDSPEEHMLKVFANGPLCPPAQ--AQVTVY 326 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN-AELTYTMTDKDYTG-- 303 I+ + + P E ++ ++ +Q + + EL T +DK Sbjct: 327 IQPMVSSEPTIKIRFVTEHKNQ-------VIMLQENEPPTVLALLELEDTSSDKGTLSLE 379 Query: 304 NVDLPITIDPRSG--WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 +P ++ ++G + TS LD E +Y + V +D Sbjct: 380 TDSMPFSLKQQAGSYLLSTSKALDFELCGEYDVTVVISDPHGARLHGREVIKVVVQDLND 439 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419 F +YE ++ E+ PG ++ + ATDAD + ++ Y IT G+ F I Q Sbjct: 440 NAPKFEQTRYETDIKENNKPGEFLLKVQATDADSHQFGKVEYRITNGSP---FRI--QEE 494 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDT--AMVQINITDANNYAPVFENAPYTAS 477 G+I V +PLD +Q+ Y+LTV A D G S A+V +N+ D N+ P F + Sbjct: 495 TGVILVTEPLDREQQGTYILTVLAQDGGDPSQEAFAIVFVNVLDMNDNPPAFPTPHFYFF 554 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 V E P + V V+ +D+D G N +I + I N+ FVI+ G + + Sbjct: 555 VSESLPHLSQVGKVTVSDADDGDNGRI---VDLRILNDKA-----PFVIDMSQGMLRSTG 606 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP---VFKQQLYTANIMEDA 594 +DRE Y L V A DGG P LS T + + V D+NDN+P + L I Sbjct: 607 EVDREKQDRYELLVVAVDGGSPVLSTTVKMTVFVEDINDNQPQVLLPSSNLSCLTISPAT 666 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNKALDRESVATH 653 G+ ++++ A D D G+N I Y++ + + F ID SG I + L E H Sbjct: 667 QAGSMITKIYAIDEDSGMNSDITYQIIASEPALQSPFQIDQHSGNITLVQHLRGEDYGMH 726 Query: 654 DLKAVAIDGGTP-PQSSTVIVHIKIED 679 L V DGG P P +T+ V++ + + Sbjct: 727 HLFIVVRDGGKPDPLQTTIWVNLLVNE 753 Score = 168 bits (409), Expect = 2e-39 Identities = 170/672 (25%), Positives = 293/672 (43%), Gaps = 48/672 (7%) Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYS-IVRVQAYDADEGVNAELTYTMTDKDY 301 ++I + D+NDNAP F + + E+ IG + ++ QA D D N + Y + Sbjct: 110 MVIVVNDINDNAPVFERNEIPLRIPEDTSIGTTFLLDDQAQDKDTANNGLIHYHLEGS-- 167 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 N I + + +LDRETQ Y L++ A D G P SATA Sbjct: 168 --NGFFGIRQEDYGLELIVQKELDRETQDNYFLVLVAVDRGSMPLSATANLSVTVTDVDD 225 Query: 362 XXXXFMPGQYEVELAEDEP-PGTPVVTLTATDAD--EDNRLHYEITGG-NTRGRFSITSQ 417 F + GT V L ATD D ++ ++ + + + R + Sbjct: 226 NCPEFDDDSPIKAIVPGLGIKGTAVAQLKATDKDLGQNAQITFSFSRQISDRAKTLFYMD 285 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTAS 477 GLI++A + ++L V A +G A Q+ + P+ + P T Sbjct: 286 RHTGLISLAVDVHTDSPEEHMLKVFA--NGPLCPPAQAQVTVY----IQPMVSSEP-TIK 338 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA--ITT 535 + V+++ + + SS+ ++ F + Q G+ ++T Sbjct: 339 IRFVTEHKNQVIMLQENEPPTVLALLELEDTSSDKGTLSLETDSMPFSLKQQAGSYLLST 398 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 +K LD E Y +TV D L +++ V D+NDN P F+Q Y +I E+ Sbjct: 399 SKALDFELCGEYDVTVVISDPHGARLHGREVIKVVVQDLNDNAPKFEQTRYETDIKENNK 458 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKALDRESVATHD 654 G + +V ATDAD G++ Y + GS F I +GVI + LDRE T+ Sbjct: 459 PGEFLLKVQATDADSHQFGKVEYRIT-----NGSPFRIQEETGVILVTEPLDREQQGTYI 513 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 L +A DGG P Q + IV + + D+ND+PP F + F++SE+ P + +G++ D Sbjct: 514 LTVLAQDGGDPSQEAFAIVFVNVLDMNDNPPAFPTPHFYFFVSESLPHLSQVGKVTVSDA 573 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---AS 771 D+G N + ++ +D F ++ QG L + ++D E + +YEL++ A S Sbjct: 574 DDGDNGRI-VDLRILNDKAPFVIDMSQGM----LRSTGEVDREK-QDRYELLVVAVDGGS 627 Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-------FGRVPAYDAD-- 822 P L V++ + V D+NDN P + ++ ++ C + P ++ A D D Sbjct: 628 PVLSTTVKMTVFVEDINDNQPQV----LLPSSNLSCLTISPATQAGSMITKIYAIDEDSG 683 Query: 823 VTDKLQYRILSGNNA--NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMM 880 + + Y+I++ A + +++ +G++TL L + + + V DG Sbjct: 684 MNSDITYQIIASEPALQSPFQIDQHSGNITLVQHLRGEDYGMHHLFIVVRDGGKPDPLQT 743 Query: 881 QLSVRLITEEML 892 + V L+ E L Sbjct: 744 TIWVNLLVNETL 755 Score = 132 bits (318), Expect = 2e-28 Identities = 100/338 (29%), Positives = 155/338 (45%), Gaps = 33/338 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ V D ND++P FE +YE ++E G +L ++ATD D + +VEY I Sbjct: 431 KVVVQDLNDNAPKFEQTRYETDIKENNKPGEFLLKVQATDADSHQFGKVEYRI-----TN 485 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 +P FRI +G +L LDRE+ Y + V A D P + Sbjct: 486 GSP-----------------FRIQEETGVILVTEPLDREQQGTYILTVLAQDGGDPSQE- 527 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + A + VN++D NDN P F + V E S+ + K+ +DAD G N I Sbjct: 528 --AFAIVFVNVLDMNDNPPAFPTPHFYFFVSE--SLPHLSQVGKVTVSDADDGDNGRIVD 583 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I N + F ID G + +D E+ Y L++ A DGGSP S T ++ + + D Sbjct: 584 LRI-LNDKAPFVIDMSQGMLRSTGEVDREKQDRYELLVVAVDGGSPVLSTTVKMTVFVED 642 Query: 250 VNDNAPRFY---TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 +NDN P+ ++L ++S G I ++ A D D G+N+++TY + + + Sbjct: 643 INDNQPQVLLPSSNLSCLTISPATQAGSMITKIYAIDEDSGMNSDITYQIIASEPA--LQ 700 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP 344 P ID SG + L E + L + DGG P Sbjct: 701 SPFQIDQHSGNITLVQHLRGEDYGMHHLFIVVRDGGKP 738 Score = 77.8 bits (183), Expect = 4e-12 Identities = 78/286 (27%), Positives = 133/286 (46%), Gaps = 21/286 (7%) Query: 632 IDPASGVIRTNKALDRESVA-TH-DLKAVAIDGGT-PPQSSTVIVHIKIEDINDSPPVFE 688 +D +G + T LDRE++ +H D + ++ P V + I + DIND+ PVFE Sbjct: 66 VDEITGDLFTKDRLDRETLCPSHQDGECTFLNTAVVSPHLDVVPMVIVVNDINDNAPVFE 125 Query: 689 SDCLTFYISENSPIGTT-IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747 + + I E++ IGTT + + +A D D N ++HY ++G SN F RQ E Sbjct: 126 RNEIPLRIPEDTSIGTTFLLDDQAQDKDTANNGLIHYHLEG---SNGF-FGIRQEDYGLE 181 Query: 748 LVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY 804 L+ +LD E+ + Y LV+ A S PL + + VTDV+DN P D I Sbjct: 182 LIVQKELDRET-QDNYFLVLVAVDRGSMPLSATANLSVTVTDVDDNCPEFDDDSPIKAIV 240 Query: 805 KDCFPVG-PFGRVPAYDADVTDKLQY-----RILSGNNANLILLNETTGSMTLSPQLNTN 858 G ++ A D D+ Q R +S L ++ TG ++L+ ++T+ Sbjct: 241 PGLGIKGTAVAQLKATDKDLGQNAQITFSFSRQISDRAKTLFYMDRHTGLISLAVDVHTD 300 Query: 859 VPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMT 904 P+ ++V + Q V + + M+ + T+++ +T Sbjct: 301 SPEEHMLKVFAN---GPLCPPAQAQVTVYIQPMVSSEPTIKIRFVT 343 >UniRef50_A1L1W7 Cluster: LOC555688 protein; n=6; Euteleostomi|Rep: LOC555688 protein - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 1078 Score = 226 bits (552), Expect = 8e-57 Identities = 164/506 (32%), Positives = 239/506 (47%), Gaps = 32/506 (6%) Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 I I DVNDNAPRF T+ +SEN G A D D G N TYT+T D G Sbjct: 108 IEIIDVNDNAPRFPTNHIDIEISENAAPGTRFPLEGASDPDSGSNGIQTYTITPNDIFG- 166 Query: 305 VDLPITID-PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 +++ D + + LDRETQ++Y +TA DGGDPP+S T Sbjct: 167 LEIKTRGDGSKIAELVVEKTLDRETQSRYTFELTAEDGGDPPKSGTVQLNIKVIDSNDNN 226 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI---TGGNTRGRFSITSQN 418 F Y V + E+ P T V+ L ATD DE + + Y T+ F I + Sbjct: 227 PVFDEPVYTVNVLENSPINTLVIDLNATDPDEGTNGEVVYSFINFVSNLTKQMFKIDPKT 286 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAP----VFENA 472 G +ITV LD ++ + + V A D G S A V +N+ D N+ AP + EN+ Sbjct: 287 G--VITVNGVLDHEELHIHEIDVQAKDLGPNSIPAHCKVIVNVIDINDNAPEIKLLSENS 344 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 V E+AP+G + +V +D+D G N ++ L + + + F Sbjct: 345 EMV-EVSENAPLGYVIALVRVSDNDSGANGKVQCRLQGNVPFRL--NEFESF------ST 395 Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592 + + LDRE Y LT+ A D G P L + + V D NDN P F + Y A ++E Sbjct: 396 LLVDGRLDREQRDMYNLTILAEDSGYPPLRSSKSFAVKVTDENDNPPYFTKPHYQAMVLE 455 Query: 593 DALVGTSVSQVGATDADVGLNGRIHYEL---DPKDREEGSFVIDPASGVIRTNKALDRES 649 + + G + V A D D+G+NG + YE+ + + S+V ++G I +A + E Sbjct: 456 NNVPGAFLLAVSARDPDLGMNGTVSYEIIKSEVRGMSVESYVTVNSNGEIYGVRAFNHED 515 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT-----FYISENSPIGT 704 T + K A DGG PP +S V I + D+ND+ PV + L I +N+ +G Sbjct: 516 TRTFEFKVSAKDGGDPPLTSNATVRIVVLDVNDNTPVMTTPPLVNGTAEVSIPKNAGVGY 575 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGD 730 + +I+A D DEG N + YSI GD Sbjct: 576 LVTQIKADDYDEGENGRLTYSISEGD 601 Score = 213 bits (520), Expect = 6e-53 Identities = 173/600 (28%), Positives = 271/600 (45%), Gaps = 58/600 (9%) Query: 2 SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 S+ C+ + I ++D ND++P F + + E A+ GT A+D D G N YT Sbjct: 100 SMEICVIK-IEIIDVNDNAPRFPTNHIDIEISENAAPGTRFPLEGASDPDSGSNGIQTYT 158 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKAT 120 I P D ++ R DG + L+ +LDRE +RYT + A Sbjct: 159 I--------TPND--------IFGLEIKTRGDGSKIAELVVEKTLDRETQSRYTFELTAE 202 Query: 121 DQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD 180 D P S T +++ +ID NDN P F E YTV+V E+ + N ++ + ATD D Sbjct: 203 DGGDPPK---SGTVQLNIKVIDSNDNNPVFDEPVYTVNVLENSPI--NTLVIDLNATDPD 257 Query: 181 VGANSAIRYAII---GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237 G N + Y+ I T+ F ID +G +++ LD+E++ + + ++A+D G S Sbjct: 258 EGTNGEVVYSFINFVSNLTKQMFKIDPKTGVITVNGVLDHEELHIHEIDVQAKDLGPNSI 317 Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQES-----VSENVPIGYSIVRVQAYDADEGVNAEL 292 ++++N+ D+NDNAP L E+ VSEN P+GY I V+ D D G N ++ Sbjct: 318 PAHCKVIVNVIDINDNAPEI--KLLSENSEMVEVSENAPLGYVIALVRVSDNDSGANGKV 375 Query: 293 TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352 + GNV + + G+LDRE + Y L + A D G PP ++ + Sbjct: 376 QCRL-----QGNVPFRLNEFESFSTLLVDGRLDREQRDMYNLTILAEDSGYPPLRSSKSF 430 Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRG 410 F Y+ + E+ PG ++ ++A D D + + YEI RG Sbjct: 431 AVKVTDENDNPPYFTKPHYQAMVLENNVPGAFLLAVSARDPDLGMNGTVSYEIIKSEVRG 490 Query: 411 RF--SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYA 466 S + N G I + + + R + VSA D G + A V+I + D N+ Sbjct: 491 MSVESYVTVNSNGEIYGVRAFNHEDTRTFEFKVSAKDGGDPPLTSNATVRIVVLDVNDNT 550 Query: 467 PVFENAPYT-----ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521 PV P S+ ++A +G V + A D D G N ++TYS IS +A+ Sbjct: 551 PVMTTPPLVNGTAEVSIPKNAGVGYLVTQIKADDYDEGENGRLTYS----ISEGDMAY-- 604 Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV-VDVNDNEPV 580 F I+ G + T K Y +TV A D G SLS + + I + D+N E + Sbjct: 605 --FEIDQINGEVRTTKTFGENAKPSYQITVVAHDHGQTSLSASAYIVIYLSPDLNAQEQI 662 Score = 212 bits (517), Expect = 1e-52 Identities = 176/606 (29%), Positives = 273/606 (45%), Gaps = 37/606 (6%) Query: 96 SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155 +G L+T+ +DR+ V R T K +S+ + I + IID NDN P+F Sbjct: 69 AGLLITKQKIDRDAVCRQTP--KCFISLEVMSNSME-ICVIKIEIIDVNDNAPRFPTNHI 125 Query: 156 TVSVDEDISV-TDNPVIAKIKATDADVGANSAIRYAIIGGNT---QMQFSID-SLSGDVS 210 + + E+ + T P+ A+D D G+N Y I + +++ D S ++ Sbjct: 126 DIEISENAAPGTRFPLEG---ASDPDSGSNGIQTYTITPNDIFGLEIKTRGDGSKIAELV 182 Query: 211 LVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENV 270 + KTLD E Y + A+DGG P +S T QL I + D NDN P F ++ +V EN Sbjct: 183 VEKTLDRETQSRYTFELTAEDGGDPPKSGTVQLNIKVIDSNDNNPVFDEPVYTVNVLENS 242 Query: 271 PIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI-TIDPRSGWVYTSGQLDRETQ 329 PI ++ + A D DEG N E+ Y+ ++ N+ + IDP++G + +G LD E Sbjct: 243 PINTLVIDLNATDPDEGTNGEVVYSFI--NFVSNLTKQMFKIDPKTGVITVNGVLDHEEL 300 Query: 330 AKYQLLVTATDGGD---PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386 +++ V A D G P VE++E+ P G + Sbjct: 301 HIHEIDVQAKDLGPNSIPAHCKVIVNVIDINDNAPEIKLLSENSEMVEVSENAPLGYVIA 360 Query: 387 TLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444 + +D D + ++ + G F + + V LD +Q Y LT+ A Sbjct: 361 LVRVSDNDSGANGKVQCRLQGNVP---FRLNEFESFSTLLVDGRLDREQRDMYNLTILAE 417 Query: 445 DSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501 DSG RS + + +TD N+ P F Y A V E+ G +L VSA D D+G+N Sbjct: 418 DSGYPPLRSSKSFA-VKVTDENDNPPYFTKPHYQAMVLENNVPGAFLLAVSARDPDLGMN 476 Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL 561 ++Y + I +E + +V G I + + E + V+A+DGG P L Sbjct: 477 GTVSYEI---IKSEVRGMSVESYVTVNSNGEIYGVRAFNHEDTRTFEFKVSAKDGGDPPL 533 Query: 562 SDTTDVEISVVDVNDNEPVFK-----QQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616 + V I V+DVNDN PV +I ++A VG V+Q+ A D D G NGR+ Sbjct: 534 TSNATVRIVVLDVNDNTPVMTTPPLVNGTAEVSIPKNAGVGYLVTQIKADDYDEGENGRL 593 Query: 617 HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID-GGTPPQSSTVIVHI 675 Y + D F ID +G +RT K + ++ + VA D G T +S IV Sbjct: 594 TYSISEGDM--AYFEIDQINGEVRTTKTFGENAKPSYQITVVAHDHGQTSLSASAYIVIY 651 Query: 676 KIEDIN 681 D+N Sbjct: 652 LSPDLN 657 Score = 192 bits (469), Expect = 9e-47 Identities = 137/443 (30%), Positives = 217/443 (48%), Gaps = 23/443 (5%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADE-DNRLH-YEITGGNTRGRFSITSQNGRGL- 422 F ++E++E+ PGT A+D D N + Y IT + G T +G + Sbjct: 120 FPTNHIDIEISENAAPGTRFPLEGASDPDSGSNGIQTYTITPNDIFGLEIKTRGDGSKIA 179 Query: 423 -ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVF 479 + V + LD + + RY ++A D G +S T + I + D+N+ PVF+ YT +V Sbjct: 180 ELVVEKTLDRETQSRYTFELTAEDGGDPPKSGTVQLNIKVIDSNDNNPVFDEPVYTVNVL 239 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E++PI T V+ ++ATD D G N ++ YS + +SN Q F I+P+TG IT N +L Sbjct: 240 ENSPINTLVIDLNATDPDEGTNGEVVYSFINFVSNLT----KQMFKIDPKTGVITVNGVL 295 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK---QQLYTANIMEDALV 596 D E + + + V A+D G S+ V ++V+D+NDN P K + + E+A + Sbjct: 296 DHEELHIHEIDVQAKDLGPNSIPAHCKVIVNVIDINDNAPEIKLLSENSEMVEVSENAPL 355 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPK-DREEGSFVIDPASGVIRTNKALDRESVATHDL 655 G ++ V +D D G NG++ L F + + + LDRE ++L Sbjct: 356 GYVIALVRVSDNDSGANGKVQCRLQGNVPFRLNEF---ESFSTLLVDGRLDREQRDMYNL 412 Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 +A D G PP S+ +K+ D ND+PP F + EN+ G + + A DPD Sbjct: 413 TILAEDSGYPPLRSSKSFAVKVTDENDNPPYFTKPHYQAMVLENNVPGAFLLAVSARDPD 472 Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQG-SDKAELVTMVDLDYESPRKKYELVIRA---AS 771 G N V Y I + S+E+ + E+ + ++E R +E + A Sbjct: 473 LGMNGTVSYEIIKSE-VRGMSVESYVTVNSNGEIYGVRAFNHEDTRT-FEFKVSAKDGGD 530 Query: 772 PPLWNDVRVEILVTDVNDNAPVM 794 PPL ++ V I+V DVNDN PVM Sbjct: 531 PPLTSNATVRIVVLDVNDNTPVM 553 Score = 165 bits (400), Expect = 2e-38 Identities = 140/482 (29%), Positives = 209/482 (43%), Gaps = 35/482 (7%) Query: 370 QYEVELAEDEPPGTPVVTLTATDADE-----DNRLHYEITGGNTRGRFSITSQNGRGLIT 424 +Y VE E+ GT + +TA DA NR Y N+ R+ + + GL+ Sbjct: 19 KYTVE--EELRAGTKIANVTA-DAKVAGFALGNRQPYLRVISNSEPRW--VNLSPAGLLI 73 Query: 425 VAQPLDFKQERRYV--LTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 Q +D R +S + +++I I D N+ AP F + E+A Sbjct: 74 TKQKIDRDAVCRQTPKCFISLEVMSNSMEICVIKIEIIDVNDNAPRFPTNHIDIEISENA 133 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 GT + A+D D G N TY+++ N+ + + + K LDRE Sbjct: 134 APGTRFPLEGASDPDSGSNGIQTYTITP---NDIFGLEIKTRGDGSKIAELVVEKTLDRE 190 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 T S Y +TA DGG P S T + I V+D NDN PVF + +YT N++E++ + T V Sbjct: 191 TQSRYTFELTAEDGGDPPKSGTVQLNIKVIDSNDNNPVFDEPVYTVNVLENSPINTLVID 250 Query: 603 VGATDADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 + ATD D G NG + Y + + F IDP +GVI N LD E + H++ A Sbjct: 251 LNATDPDEGTNGEVVYSFINFVSNLTKQMFKIDPKTGVITVNGVLDHEELHIHEIDVQAK 310 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPP---VFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 D G + V + + DIND+ P + + +SEN+P+G I +R D D G Sbjct: 311 DLGPNSIPAHCKVIVNVIDINDNAPEIKLLSENSEMVEVSENAPLGYVIALVRVSDNDSG 370 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPL 774 N V ++G + + + L+ LD E R Y L I A PPL Sbjct: 371 ANGKVQCRLQG-----NVPFRLNEFESFSTLLVDGRLDREQ-RDMYNLTILAEDSGYPPL 424 Query: 775 WNDVRVEILVTDVNDNAPVMK----DFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYR 830 + + VTD NDN P ++ NN F + R P D + + Y Sbjct: 425 RSSKSFAVKVTDENDNPPYFTKPHYQAMVLENNVPGAFLLAVSARDP--DLGMNGTVSYE 482 Query: 831 IL 832 I+ Sbjct: 483 II 484 Score = 155 bits (376), Expect = 2e-35 Identities = 136/499 (27%), Positives = 223/499 (44%), Gaps = 37/499 (7%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 + I V+D ND++PVF+ Y +V E + T V+ L ATD D G N EV Y+ Sbjct: 213 VQLNIKVIDSNDNNPVFDEPVYTVNVLENSPINTLVIDLNATDPDEGTNGEVVYSF---- 268 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 +N + +F+ID ++G + LD E++ + + V+A D P Sbjct: 269 ---IN---------FVSNLTKQMFKIDPKTGVITVNGVLDHEELHIHEIDVQAKD-LGPN 315 Query: 127 SDRLSSTATIHVNIIDDNDNYPQ---FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA 183 S + + + VN+ID NDN P+ SE + V V E+ + VIA ++ +D D GA Sbjct: 316 S--IPAHCKVIVNVIDINDNAPEIKLLSENSEMVEVSENAPL--GYVIALVRVSDNDSGA 371 Query: 184 NSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 N ++ + GN + + + + LD EQ Y L I A+D G P ++ Sbjct: 372 NGKVQ-CRLQGNVPFRLNEFESFSTLLVDGRLDREQRDMYNLTILAEDSGYPPLRSSKSF 430 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 + + D NDN P F +Q V EN G ++ V A D D G+N ++Y + + G Sbjct: 431 AVKVTDENDNPPYFTKPHYQAMVLENNVPGAFLLAVSARDPDLGMNGTVSYEIIKSEVRG 490 Query: 304 -NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT-----XXXXXX 357 +V+ +T++ +G +Y + E ++ V+A DGGDPP ++ AT Sbjct: 491 MSVESYVTVN-SNGEIYGVRAFNHEDTRTFEFKVSAKDGGDPPLTSNATVRIVVLDVNDN 549 Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSIT 415 + G EV + ++ G V + A D D E+ RL Y I+ G+ F I Sbjct: 550 TPVMTTPPLVNGTAEVSIPKNAGVGYLVTQIKADDYDEGENGRLTYSISEGD-MAYFEID 608 Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYT 475 NG + + + Y +TV A D G S +A I I + + + P Sbjct: 609 QINGE--VRTTKTFGENAKPSYQITVVAHDHGQTSLSASAYIVIYLSPDLNAQEQIGPVN 666 Query: 476 ASVFEDAPIGTTVLVVSAT 494 S+ +G+ +++ T Sbjct: 667 LSLIFIIALGSIAVILFVT 685 >UniRef50_Q60I64 Cluster: Cadherin-related neuronal receptor constant; n=6; Clupeocephala|Rep: Cadherin-related neuronal receptor constant - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 1009 Score = 225 bits (550), Expect = 1e-56 Identities = 171/592 (28%), Positives = 269/592 (45%), Gaps = 57/592 (9%) Query: 4 PFCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 PF H + +LD ND+SP+F +Y+ + EGA G A D D N+ Y + Sbjct: 115 PFEQHSVDVEILDANDNSPLFPRDEYQLEISEGAQPGARFSIEGAQDSDDASNSVRHYRL 174 Query: 63 ---ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKA 119 E + D+ P DG+ L+ + DRE + + L+ A Sbjct: 175 TPNEHLALDSTKPP------------------ADGKQVELVLKKPFDRELLQSHQFLITA 216 Query: 120 TDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA 179 TD SP S TA I+V ++D NDN P F Y V + E+ V ++ K+ ATD Sbjct: 217 TDGGSPPR---SGTARINVRVLDTNDNVPVFDSSVYKVKLRENSPV--GALVIKLNATDR 271 Query: 180 DVGANSAIRYAIIG---GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS 236 D G+N + Y+ + FS+D+ SG++ + +DYE+ SY + I+A D G + Sbjct: 272 DEGSNGEVYYSFSSYTPDKVRQMFSVDADSGEIRVKSNVDYEETNSYEMYIQAADRGQGA 331 Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 + ++++ + DVNDN P S V E+ + + D D G N +++ + Sbjct: 332 VAVHCKVVVEVLDVNDNPPEIVLSSLSSPVREDARADTVVALISINDKDSGQNKQVSLDI 391 Query: 297 TDKDYTGNVDLPITIDP-RSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354 DLP I R+ + + TS LDRET + Y + VTATDGG PP S++ T Sbjct: 392 IPP------DLPFKIKSFRNHYTIVTSALLDRETISSYNVTVTATDGGTPPLSSSMTVRV 445 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRG-- 410 F Y V ++E+ P P+ + ATD D E+ R+ Y I N G Sbjct: 446 EVADINDNPPRFKQTSYTVYVSENNAPSAPLCVIKATDPDAGENARITYTILTDNNHGVS 505 Query: 411 -RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAP 467 ++ + G + + DF++ R + V A D+G S A V I I D+N+++P Sbjct: 506 VGSYVSVKPATGEVYALRSFDFEKLREFHFQVKAQDNGVPPLSRVATVYIYIMDSNDHSP 565 Query: 468 VFENA-----PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522 F A T ++ + G V A D D G NA + Y+L A Sbjct: 566 QFARAVANGSHSTETILRHSEAGVLVSRALAWDLDAGENAWLLYNLHH-------APELD 618 Query: 523 QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 F I+ TG I T + + + + + LTV RD G P+ S +T + ++V+++ Sbjct: 619 LFKIHEHTGEIRTTRRVIEDNSTVFSLTVHVRDHGSPARSASTTINVAVMEL 670 Score = 223 bits (546), Expect = 4e-56 Identities = 171/575 (29%), Positives = 254/575 (44%), Gaps = 26/575 (4%) Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR-LVIRAQDGGSPSRSNTTQL 243 SA R I + F+I+ +G + + +D E + + + D S + Sbjct: 62 SARRIRISSDTARRYFNINHKTGKLVISDRIDRETLCEFSGTCTLSLDVVLESPFEQHSV 121 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 + I D NDN+P F +Q +SE G A D+D+ N+ Y +T ++ Sbjct: 122 DVEILDANDNSPLFPRDEYQLEISEGAQPGARFSIEGAQDSDDASNSVRHYRLTPNEHLA 181 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 D + + DRE +Q L+TATDGG PPRS TA Sbjct: 182 LDSTKPPADGKQVELVLKKPFDRELLQSHQFLITATDGGSPPRSGTARINVRVLDTNDNV 241 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI---TGGNTRGRFSITSQN 418 F Y+V+L E+ P G V+ L ATD DE + ++Y T R FS+ + + Sbjct: 242 PVFDSSVYKVKLRENSPVGALVIKLNATDRDEGSNGEVYYSFSSYTPDKVRQMFSVDADS 301 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTA 476 G I V +D+++ Y + + A D G + V + + D N+ P + ++ Sbjct: 302 GE--IRVKSNVDYEETNSYEMYIQAADRGQGAVAVHCKVVVEVLDVNDNPPEIVLSSLSS 359 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 V EDA T V ++S D D G N Q+ S +I + + F N T I T+ Sbjct: 360 PVREDARADTVVALISINDKDSGQNKQV----SLDIIPPDLPFKIKSFR-NHYT--IVTS 412 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 LLDRET+S Y +TVTA DGG P LS + V + V D+NDN P FKQ YT + E+ Sbjct: 413 ALLDRETISSYNVTVTATDGGTPPLSSSMTVRVEVADINDNPPRFKQTSYTVYVSENNAP 472 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDR---EEGSFV-IDPASGVIRTNKALDRESVAT 652 + + ATD D G N RI Y + + GS+V + PA+G + ++ D E + Sbjct: 473 SAPLCVIKATDPDAGENARITYTILTDNNHGVSVGSYVSVKPATGEVYALRSFDFEKLRE 532 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF-----ESDCLTFYISENSPIGTTIG 707 + A D G PP S V+I I D ND P F T I +S G + Sbjct: 533 FHFQVKAQDNGVPPLSRVATVYIYIMDSNDHSPQFARAVANGSHSTETILRHSEAGVLVS 592 Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 A D D G NA + Y++ + + F + G Sbjct: 593 RALAWDLDAGENAWLLYNLHHAPELDLFKIHEHTG 627 Score = 208 bits (507), Expect = 2e-51 Identities = 158/603 (26%), Positives = 264/603 (43%), Gaps = 21/603 (3%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F I+ ++G L+ +DRE + ++ T V + ++ V I+D NDN P Sbjct: 77 FNINHKTGKLVISDRIDRETLCEFSGT--CTLSLDVVLESPFEQHSVDVEILDANDNSPL 134 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN----TQMQFSIDSL 205 F Y + + E + A D+D +NS Y + + D Sbjct: 135 FPRDEYQLEISE--GAQPGARFSIEGAQDSDDASNSVRHYRLTPNEHLALDSTKPPADGK 192 Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265 ++ L K D E ++S++ +I A DGGSP RS T ++ + + D NDN P F +S+++ Sbjct: 193 QVELVLKKPFDRELLQSHQFLITATDGGSPPRSGTARINVRVLDTNDNVPVFDSSVYKVK 252 Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYT-GNVDLPITIDPRSGWVYTSGQL 324 + EN P+G ++++ A D DEG N E+ Y+ + YT V ++D SG + + Sbjct: 253 LRENSPVGALVIKLNATDRDEGSNGEVYYSFS--SYTPDKVRQMFSVDADSGEIRVKSNV 310 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 D E Y++ + A D G + + + ED T Sbjct: 311 DYEETNSYEMYIQAADRGQGAVAVHCKVVVEVLDVNDNPPEIVLSSLSSPVREDARADTV 370 Query: 385 VVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444 V ++ D D + F I S I + LD + Y +TV+AT Sbjct: 371 VALISINDKDSGQNKQVSLDIIPPDLPFKIKSFRNHYTIVTSALLDRETISSYNVTVTAT 430 Query: 445 DSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502 D G S + V++ + D N+ P F+ YT V E+ + V+ ATD D G NA Sbjct: 431 DGGTPPLSSSMTVRVEVADINDNPPRFKQTSYTVYVSENNAPSAPLCVIKATDPDAGENA 490 Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 +ITY++ ++ +N V+ + P TG + + D E + + V A+D GVP LS Sbjct: 491 RITYTILTD-NNHGVS-VGSYVSVKPATGEVYALRSFDFEKLREFHFQVKAQDNGVPPLS 548 Query: 563 DTTDVEISVVDVNDNEPVFKQQL-----YTANIMEDALVGTSVSQVGATDADVGLNGRIH 617 V I ++D ND+ P F + + T I+ + G VS+ A D D G N + Sbjct: 549 RVATVYIYIMDSNDHSPQFARAVANGSHSTETILRHSEAGVLVSRALAWDLDAGENAWLL 608 Query: 618 YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 Y L E F I +G IRT + + ++ L D G+P +S++ +++ + Sbjct: 609 YNLHHAP-ELDLFKIHEHTGEIRTTRRVIEDNSTVFSLTVHVRDHGSPARSASTTINVAV 667 Query: 678 EDI 680 ++ Sbjct: 668 MEL 670 Score = 200 bits (487), Expect = 6e-49 Identities = 130/440 (29%), Positives = 225/440 (51%), Gaps = 22/440 (5%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRL--HYEITGGNTRGRFSITSQ-NGRGL 422 F +Y++E++E PG A D+D+ + HY +T S +G+ + Sbjct: 135 FPRDEYQLEISEGAQPGARFSIEGAQDSDDASNSVRHYRLTPNEHLALDSTKPPADGKQV 194 Query: 423 -ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVF 479 + + +P D + + + ++ATD G RS TA + + + D N+ PVF+++ Y + Sbjct: 195 ELVLKKPFDRELLQSHQFLITATDGGSPPRSGTARINVRVLDTNDNVPVFDSSVYKVKLR 254 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E++P+G V+ ++ATD D G N ++ YS SS ++ Q F ++ +G I + Sbjct: 255 ENSPVGALVIKLNATDRDEGSNGEVYYSFSSYTPDKV----RQMFSVDADSGEIRVKSNV 310 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 D E + Y + + A D G +++ V + V+DVNDN P ++ + EDA T Sbjct: 311 DYEETNSYEMYIQAADRGQGAVAVHCKVVVEVLDVNDNPPEIVLSSLSSPVREDARADTV 370 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG--VIRTNKALDRESVATHDLKA 657 V+ + D D G N ++ ++ P D F I I T+ LDRE+++++++ Sbjct: 371 VALISINDKDSGQNKQVSLDIIPPDLP---FKIKSFRNHYTIVTSALLDRETISSYNVTV 427 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A DGGTPP SS++ V +++ DIND+PP F+ T Y+SEN+ + I+A DPD G Sbjct: 428 TATDGGTPPLSSSMTVRVEVADINDNPPRFKQTSYTVYVSENNAPSAPLCVIKATDPDAG 487 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKA--ELVTMVDLDYESPRKKYELVIRAAS---P 772 NA + Y+I D+++ S+ + A E+ + D+E R+ + ++A P Sbjct: 488 ENARITYTILT-DNNHGVSVGSYVSVKPATGEVYALRSFDFEKLRE-FHFQVKAQDNGVP 545 Query: 773 PLWNDVRVEILVTDVNDNAP 792 PL V I + D ND++P Sbjct: 546 PLSRVATVYIYIMDSNDHSP 565 Score = 160 bits (388), Expect = 6e-37 Identities = 111/389 (28%), Positives = 176/389 (45%), Gaps = 15/389 (3%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 V + I DAN+ +P+F Y + E A G + A DSD N+ Y L+ N Sbjct: 121 VDVEILDANDNSPLFPRDEYQLEISEGAQPGARFSIEGAQDSDDASNSVRHYRLTP---N 177 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 E +A + + + + K DRE + + +TA DGG P S T + + V+D Sbjct: 178 EHLALDSTKPPADGKQVELVLKKPFDRELLQSHQFLITATDGGSPPRSGTARINVRVLDT 237 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP--KDREEGSFVI 632 NDN PVF +Y + E++ VG V ++ ATD D G NG ++Y D+ F + Sbjct: 238 NDNVPVFDSSVYKVKLRENSPVGALVIKLNATDRDEGSNGEVYYSFSSYTPDKVRQMFSV 297 Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692 D SG IR +D E ++++ A D G + V +++ D+ND+PP L Sbjct: 298 DADSGEIRVKSNVDYEETNSYEMYIQAADRGQGAVAVHCKVVVEVLDVNDNPPEIVLSSL 357 Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752 + + E++ T + I +D D G N V I D + + + +VT Sbjct: 358 SSPVREDARADTVVALISINDKDSGQNKQVSLDIIPPD----LPFKIKSFRNHYTIVTSA 413 Query: 753 DLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809 LD E+ Y + + A +PPL + + V + V D+NDN P K ++ P Sbjct: 414 LLDRETI-SSYNVTVTATDGGTPPLSSSMTVRVEVADINDNPPRFKQTSYTVYVSENNAP 472 Query: 810 VGPFGRVPAYDADVTD--KLQYRILSGNN 836 P + A D D + ++ Y IL+ NN Sbjct: 473 SAPLCVIKATDPDAGENARITYTILTDNN 501 Score = 58.4 bits (135), Expect = 3e-06 Identities = 48/185 (25%), Positives = 76/185 (41%), Gaps = 4/185 (2%) Query: 630 FVIDPASGVIRTNKALDRESVATHD-LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688 F I+ +G + + +DRE++ +++D V ++I D ND+ P+F Sbjct: 77 FNINHKTGKLVISDRIDRETLCEFSGTCTLSLDVVLESPFEQHSVDVEILDANDNSPLFP 136 Query: 689 SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAEL 748 D ISE + G A D D+ N+V HY + + S + + EL Sbjct: 137 RDEYQLEISEGAQPGARFSIEGAQDSDDASNSVRHYRLTPNEHLALDSTKPPADGKQVEL 196 Query: 749 VTMVDLDYESPRKKYELVIR--AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKD 806 V D E + L+ SPP R+ + V D NDN PV D + ++ Sbjct: 197 VLKKPFDRELLQSHQFLITATDGGSPPRSGTARINVRVLDTNDNVPVF-DSSVYKVKLRE 255 Query: 807 CFPVG 811 PVG Sbjct: 256 NSPVG 260 >UniRef50_Q9Y5F3 Cluster: Protocadherin beta 1 precursor; n=260; Amniota|Rep: Protocadherin beta 1 precursor - Homo sapiens (Human) Length = 818 Score = 225 bits (549), Expect = 2e-56 Identities = 175/629 (27%), Positives = 289/629 (45%), Gaps = 40/629 (6%) Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDG-GSPS 236 +VG +A ++ +M F + +GD+ + + LD E + ++ V+ + P Sbjct: 55 EVGKLAARGARLVSEGNKMHFRLHRKTGDLFVKEKLDRESLCGKADPCVLHFEVVLVEPL 114 Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 +S + + + D+NDNAP F + E+ P+G A D D G+N YT+ Sbjct: 115 QSFRAE--VRVFDINDNAPVFLNKEPLLKIPESTPLGSRFPLQSAQDLDVGLNGLQNYTL 172 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 + Y + P+ + + LDRE Q + L +TA DGG PP+S TA Sbjct: 173 SANGYFHLHTRFCSHGPKYAELVLNKPLDREEQPEVNLTITAVDGGSPPKSGTAHIHVVV 232 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTR--GRF 412 F Y +++E+ P G+ V T+TA D DE + + Y + F Sbjct: 233 LDVNDHVPQFSRLVYRAQVSENSPNGSLVATVTAVDLDEGTNKAITYSLAQNPEAILKTF 292 Query: 413 SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENA 472 I QNG + + PLDF+ Y + + ATD GG S + V + + D N+ P + Sbjct: 293 QIDPQNGE--VRLRGPLDFEAIETYDIDIQATDGGGLSAHSKVLVEVVDVNDNPPEVMVS 350 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG- 531 ++ + ED+P T V + + D D+ + ++T L D FVI P G Sbjct: 351 SVSSPLPEDSPPQTVVALFTIRDRDIRVGGKVTCFL----------REDLPFVIKPTFGN 400 Query: 532 --AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589 ++ T++ LDRE +SGY +T+ A D G PSLS T +E+ + DVNDN P+F++ Y Sbjct: 401 SYSLVTDRSLDREEVSGYNITIVAMDTGPPSLSAETMIEVLISDVNDNPPIFREDSYILT 460 Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYE-LDPKDREEGSFV---IDPASGVIRTNKAL 645 + E+ + +V A D D+G N +I Y L PK+ + F I+ +G + + + Sbjct: 461 VRENNSPAVFIGKVHAEDLDLGENAQITYSLLPPKNGDLSVFAYISINSGNGKLYALRTM 520 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV----FESDCL--TFYISEN 699 D E++ A DGG SS V V + + D ND+ P+ ++ L + + Sbjct: 521 DYEAIQDFQFVVKATDGGFLSLSSQVTVRVVVLDDNDNRPMILYPLQNGTLPCNDLVPRS 580 Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759 + G + ++ A D D G N+ + Y + D FS++ + G E+ T+ + P Sbjct: 581 AEAGYLVTKVVAVDGDSGQNSWLSYHLLKATDLGLFSVQRQNG----EIHTLRQISERDP 636 Query: 760 --RKKYELVIRAASPPLWNDVRVEILVTD 786 +K LV P L V + IL+ D Sbjct: 637 MMQKLIILVQDHGQPALSTTVSLNILLVD 665 Score = 203 bits (496), Expect = 5e-50 Identities = 180/605 (29%), Positives = 262/605 (43%), Gaps = 29/605 (4%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 FR+ ++G L + LDRE + + V S A V + D NDN P Sbjct: 75 FRLHRKTGDLFVKEKLDRESLCGKADPCVLHFEVVLVEPLQSFRA--EVRVFDINDNAPV 132 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG---NTQMQF-SIDSL 205 F K + + E + + A D DVG N Y + + +F S Sbjct: 133 FLNKEPLLKIPESTPLGSRFPLQ--SAQDLDVGLNGLQNYTLSANGYFHLHTRFCSHGPK 190 Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265 ++ L K LD E+ L I A DGGSP +S T + + + DVND+ P+F +++ Sbjct: 191 YAELVLNKPLDREEQPEVNLTITAVDGGSPPKSGTAHIHVVVLDVNDHVPQFSRLVYRAQ 250 Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325 VSEN P G + V A D DEG N +TY++ + IDP++G V G LD Sbjct: 251 VSENSPNGSLVATVTAVDLDEGTNKAITYSLAQNPEA--ILKTFQIDPQNGEVRLRGPLD 308 Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 E Y + + ATDGG SA + M L ED PP T V Sbjct: 309 FEAIETYDIDIQATDGGG--LSAHSKVLVEVVDVNDNPPEVMVSSVSSPLPEDSPPQTVV 366 Query: 386 VTLTATDADEDNRLHYEITGGNTRG-RFSI--TSQNGRGLITVAQPLDFKQERRYVLTVS 442 T D D R+ ++T F I T N L+T + LD ++ Y +T+ Sbjct: 367 ALFTI--RDRDIRVGGKVTCFLREDLPFVIKPTFGNSYSLVT-DRSLDREEVSGYNITIV 423 Query: 443 ATDSGGRSDTA--MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 A D+G S +A M+++ I+D N+ P+F Y +V E+ + V A D D+G Sbjct: 424 AMDTGPPSLSAETMIEVLISDVNDNPPIFREDSYILTVRENNSPAVFIGKVHAEDLDLGE 483 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560 NAQITYSL + + IN G + + +D E + + V A DGG S Sbjct: 484 NAQITYSLLPPKNGDLSVF--AYISINSGNGKLYALRTMDYEAIQDFQFVVKATDGGFLS 541 Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV------GTSVSQVGATDADVGLNG 614 LS V + V+D NDN P+ L + + LV G V++V A D D G N Sbjct: 542 LSSQVTVRVVVLDDNDNRPMILYPLQNGTLPCNDLVPRSAEAGYLVTKVVAVDGDSGQNS 601 Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674 + Y L K + G F + +G I T + + L + D G P S+TV ++ Sbjct: 602 WLSYHL-LKATDLGLFSVQRQNGEIHTLRQISERDPMMQKLIILVQDHGQPALSTTVSLN 660 Query: 675 IKIED 679 I + D Sbjct: 661 ILLVD 665 Score = 172 bits (418), Expect = 1e-40 Identities = 133/443 (30%), Positives = 209/443 (47%), Gaps = 22/443 (4%) Query: 456 QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515 ++ + D N+ APVF N + E P+G+ + SA D DVG+N Y+LS+ N Sbjct: 120 EVRVFDINDNAPVFLNKEPLLKIPESTPLGSRFPLQSAQDLDVGLNGLQNYTLSA---NG 176 Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575 H + P+ + NK LDRE LT+TA DGG P S T + + V+DVN Sbjct: 177 YFHLHTRFCSHGPKYAELVLNKPLDREEQPEVNLTITAVDGGSPPKSGTAHIHVVVLDVN 236 Query: 576 DNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE-GSFVIDP 634 D+ P F + +Y A + E++ G+ V+ V A D D G N I Y L +F IDP Sbjct: 237 DHVPQFSRLVYRAQVSENSPNGSLVATVTAVDLDEGTNKAITYSLAQNPEAILKTFQIDP 296 Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694 +G +R LD E++ T+D+ A DGG S V+V ++ D+ND+PP ++ Sbjct: 297 QNGEVRLRGPLDFEAIETYDIDIQATDGGGLSAHSKVLV--EVVDVNDNPPEVMVSSVSS 354 Query: 695 YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDL 754 + E+SP T + D D V ++ + F ++ G+ + LVT L Sbjct: 355 PLPEDSPPQTVVALFTIRDRDIRVGGKVTCFLR---EDLPFVIKPTFGNSYS-LVTDRSL 410 Query: 755 DYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811 D E Y + I A P L + +E+L++DVNDN P+ ++ I ++ P Sbjct: 411 DREEV-SGYNITIVAMDTGPPSLSAETMIEVLISDVNDNPPIFREDSYILTVRENNSPAV 469 Query: 812 PFGRVPAYDADVTDKLQ--YRILSGNNANL-----ILLNETTGSMTLSPQLNTNVPKLAT 864 G+V A D D+ + Q Y +L N +L I +N G + ++ + Sbjct: 470 FIGKVHAEDLDLGENAQITYSLLPPKNGDLSVFAYISINSGNGKLYALRTMDYEAIQDFQ 529 Query: 865 MEVSVTDGVNEIKAMMQLSVRLI 887 V TDG + Q++VR++ Sbjct: 530 FVVKATDG-GFLSLSSQVTVRVV 551 Score = 163 bits (397), Expect = 5e-38 Identities = 161/595 (27%), Positives = 250/595 (42%), Gaps = 59/595 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ V D ND++PVF ++ + E G+ A D D+G N YT+ Sbjct: 120 EVRVFDINDNAPVFLNKEPLLKIPESTPLGSRFPLQSAQDLDVGLNGLQNYTLS------ 173 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGA-LLTRASLDREKVARYTVLVKATDQASPVSD 128 + F G A L+ LDRE+ + + A D SP Sbjct: 174 ----------ANGYFHLHTRFCSHGPKYAELVLNKPLDREEQPEVNLTITAVDGGSPPK- 222 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 S TA IHV ++D ND+ PQFS Y V E + + ++A + A D D G N AI Sbjct: 223 --SGTAHIHVVVLDVNDHVPQFSRLVYRAQVSE--NSPNGSLVATVTAVDLDEGTNKAIT 278 Query: 189 YAIIGGNTQM--QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 Y++ + F ID +G+V L LD+E + +Y + I+A DGG S +++L+ Sbjct: 279 YSLAQNPEAILKTFQIDPQNGEVRLRGPLDFEAIETYDIDIQATDGGGLSAH--SKVLVE 336 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + DVNDN P S + E+ P + D D V ++T + + D Sbjct: 337 VVDVNDNPPEVMVSSVSSPLPEDSPPQTVVALFTIRDRDIRVGGKVTCFLRE-------D 389 Query: 307 LPITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 LP I P G Y T LDRE + Y + + A D G P SA Sbjct: 390 LPFVIKPTFGNSYSLVTDRSLDREEVSGYNITIVAMDTGPPSLSAETMIEVLISDVNDNP 449 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEI---TGGNTRGRFSITSQN 418 F Y + + E+ P + + A D D E+ ++ Y + G+ I+ + Sbjct: 450 PIFREDSYILTVRENNSPAVFIGKVHAEDLDLGENAQITYSLLPPKNGDLSVFAYISINS 509 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPV----FENA 472 G G + + +D++ + + V ATD G S V++ + D N+ P+ +N Sbjct: 510 GNGKLYALRTMDYEAIQDFQFVVKATDGGFLSLSSQVTVRVVVLDDNDNRPMILYPLQNG 569 Query: 473 --PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 P V A G V V A D D G N+ ++Y L A F + Q Sbjct: 570 TLPCNDLVPRSAEAGYLVTKVVAVDGDSGQNSWLSYHLLK-------ATDLGLFSVQRQN 622 Query: 531 GAI-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584 G I T ++ +R+ M L+ + +D G P+LS T + I +VD +EP + Q Sbjct: 623 GEIHTLRQISERDPMMQKLI-ILVQDHGQPALSTTVSLNILLVD-GFSEPYLQFQ 675 Score = 142 bits (344), Expect = 1e-31 Identities = 132/464 (28%), Positives = 201/464 (43%), Gaps = 41/464 (8%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 H + VLD NDH P F Y A V E + +G+ V T+ A D D G N + Y++ Sbjct: 227 HIHVVVLDVNDHVPQFSRLVYRAQVSENSPNGSLVATVTAVDLDEGTNKAITYSL----- 281 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 NPE + F+ID ++G + R LD E + Y + ++ATD Sbjct: 282 -AQNPE-----------AILKTFQIDPQNGEVRLRGPLDFEAIETYDIDIQATDGGG--- 326 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 LS+ + + V ++D NDN P+ + + + ED V+A D D+ + Sbjct: 327 --LSAHSKVLVEVVDVNDNPPEVMVSSVSSPLPED--SPPQTVVALFTIRDRDIRVGGKV 382 Query: 188 RYAIIGGNTQMQFSIDSLSGD-VSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 + + F I G+ SLV ++LD E+V Y + I A D G PS S T + Sbjct: 383 TCFL---REDLPFVIKPTFGNSYSLVTDRSLDREEVSGYNITIVAMDTGPPSLSAETMIE 439 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT-MTDKDYTG 303 + I DVNDN P F + +V EN I +V A D D G NA++TY+ + K+ Sbjct: 440 VLISDVNDNPPIFREDSYILTVRENNSPAVFIGKVHAEDLDLGENAQITYSLLPPKNGDL 499 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 +V I+I+ +G +Y +D E +Q +V ATDGG S+ T Sbjct: 500 SVFAYISINSGNGKLYALRTMDYEAIQDFQFVVKATDGGFLSLSSQVTVRVVVLDDNDNR 559 Query: 364 XXFM-PGQYEVELAEDEPP-----GTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSIT 415 + P Q D P G V + A D D +++ L Y + G FS+ Sbjct: 560 PMILYPLQNGTLPCNDLVPRSAEAGYLVTKVVAVDGDSGQNSWLSYHLLKATDLGLFSVQ 619 Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINI 459 QNG I + + + L + D G + + V +NI Sbjct: 620 RQNGE--IHTLRQISERDPMMQKLIILVQDHGQPALSTTVSLNI 661 >UniRef50_Q60H65 Cluster: Protocadherin1-alpha-av15-vCP; n=75; Eukaryota|Rep: Protocadherin1-alpha-av15-vCP - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 939 Score = 224 bits (548), Expect = 2e-56 Identities = 171/612 (27%), Positives = 280/612 (45%), Gaps = 36/612 (5%) Query: 87 QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIH---VNIIDD 143 + +F ++ G L + LDRE V ++T + L + IH V++ID Sbjct: 74 ESMFSVNQNDGVLYVKGKLDRENVCE-----RSTPCLINLKIALENPLEIHYVTVDVIDV 128 Query: 144 NDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSID 203 ND+ P F E+ + + E +V A D D G+NS Y + + I Sbjct: 129 NDHAPMFPEQEKRLEISE--TVLPGARFQLQAARDPDSGSNSVQTYKL-SHTEYFRIEIK 185 Query: 204 SLSGD-----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY 258 D + L K LD E +S +L + A DGG P +S ++I++ D+NDNAP F Sbjct: 186 DRYEDGKVPVLILQKPLDREVTKSIKLQLTALDGGRPPKSGKMTIIIDVLDINDNAPVFI 245 Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV 318 ++ +++EN P+G +I+RV A D DEG N + Y++ D + ++P +G + Sbjct: 246 KEVYSVTLNENTPVGTTILRVNATDLDEGQNGVVVYSL-GHDVNDKLRKLFNVNPVTGEI 304 Query: 319 YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAED 378 +G LD E + Y++ + A+D G P + + + ED Sbjct: 305 VVTGLLDFEVKDIYEIDIQASDKGIAPLTTDKSVTIKIADVNDNEPQIEVTSLSSTIPED 364 Query: 379 EPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436 PGT V ++ +D D + R+ ++ + +N L+T + LD + Sbjct: 365 SKPGTTVALISVSDLDSGINGRVTCSLSENIPFQLMPSSQENTYSLVTTS-ALDRETIAH 423 Query: 437 YVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494 Y +T+ A D+G S V + I+D N+ +P F ++PY V E+ G ++ VSA+ Sbjct: 424 YDITLEAKDAGQPPLSSVKSVTVQISDVNDNSPEFSSSPYAFYVMENNAPGKSLFSVSAS 483 Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETMSGYLLTVTA 553 D D G N+ ++Y + + E + F+ IN + G I K D ET + + A Sbjct: 484 DKDTGENSAVSYQIWRDGGAE---NKFTSFININSENGEIYALKSFDFETSKTFQFHILA 540 Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN--------IMEDALVGTSVSQVGA 605 D G PSLS V + ++D NDN PV + +AN I + G V++V A Sbjct: 541 TDSGSPSLSSNVTVNVFILDQNDNVPVILYPV-SANGSAEGVEEIPRNVNAGHLVTKVRA 599 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 DAD+G NG + + L + E F +D +G IRT ++ A H L + D G Sbjct: 600 YDADIGYNGWLLFSLQ-EVSEHSLFALDRYTGQIRTLRSFTETDEAQHKLVILVKDNGNV 658 Query: 666 PQSSTVIVHIKI 677 S+T V +K+ Sbjct: 659 SLSATATVIVKV 670 Score = 217 bits (531), Expect = 3e-54 Identities = 150/500 (30%), Positives = 239/500 (47%), Gaps = 24/500 (4%) Query: 310 TIDPRSGWVYTSGQLDRET--QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 +++ G +Y G+LDRE + L+ + P F Sbjct: 78 SVNQNDGVLYVKGKLDRENVCERSTPCLINLKIALENPLEIHYVTVDVIDVNDHAPM-FP 136 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG-RFSITSQNGRGLITVA 426 + +E++E PG A D D + +T R I + G + V Sbjct: 137 EQEKRLEISETVLPGARFQLQAARDPDSGSNSVQTYKLSHTEYFRIEIKDRYEDGKVPVL 196 Query: 427 ---QPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFED 481 +PLD + + L ++A D G +S + I++ D N+ APVF Y+ ++ E+ Sbjct: 197 ILQKPLDREVTKSIKLQLTALDGGRPPKSGKMTIIIDVLDINDNAPVFIKEVYSVTLNEN 256 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 P+GTT+L V+ATD D G N + YSL +++++ + F +NP TG I LLD Sbjct: 257 TPVGTTILRVNATDLDEGQNGVVVYSLGHDVNDKL----RKLFNVNPVTGEIVVTGLLDF 312 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 E Y + + A D G+ L+ V I + DVNDNEP + ++ I ED+ GT+V+ Sbjct: 313 EVKDIYEIDIQASDKGIAPLTTDKSVTIKIADVNDNEPQIEVTSLSSTIPEDSKPGTTVA 372 Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV----IRTNKALDRESVATHDLKA 657 + +D D G+NGR+ L E F + P+S + T ALDRE++A +D+ Sbjct: 373 LISVSDLDSGINGRVTCSLS----ENIPFQLMPSSQENTYSLVTTSALDRETIAHYDITL 428 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A D G PP SS V ++I D+ND+ P F S FY+ EN+ G ++ + A D D G Sbjct: 429 EAKDAGQPPLSSVKSVTVQISDVNDNSPEFSSSPYAFYVMENNAPGKSLFSVSASDKDTG 488 Query: 718 PNAVVHYSI-KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR--KKYELVIRAASPPL 774 N+ V Y I + G N F+ S+ E+ + D+E+ + + + L + SP L Sbjct: 489 ENSAVSYQIWRDGGAENKFTSFININSENGEIYALKSFDFETSKTFQFHILATDSGSPSL 548 Query: 775 WNDVRVEILVTDVNDNAPVM 794 ++V V + + D NDN PV+ Sbjct: 549 SSNVTVNVFILDQNDNVPVI 568 Score = 213 bits (520), Expect = 6e-53 Identities = 168/574 (29%), Positives = 260/574 (45%), Gaps = 29/574 (5%) Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDGGSPSRSNTTQLLIN 246 + I+ + + FS++ G + + LD E V RS +I + + + ++ Sbjct: 66 FRIVSTSGESMFSVNQNDGVLYVKGKLDRENVCERSTPCLINLKIA-LENPLEIHYVTVD 124 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + DVND+AP F + +SE V G A D D G N+ TY ++ +Y Sbjct: 125 VIDVNDHAPMFPEQEKRLEISETVLPGARFQLQAARDPDSGSNSVQTYKLSHTEYFRIEI 184 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 D + + LDRE +L +TA DGG PP+S T F Sbjct: 185 KDRYEDGKVPVLILQKPLDREVTKSIKLQLTALDGGRPPKSGKMTIIIDVLDINDNAPVF 244 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEI---TGGNTRGRFSITSQNGRG 421 + Y V L E+ P GT ++ + ATD DE + Y + R F++ G Sbjct: 245 IKEVYSVTLNENTPVGTTILRVNATDLDEGQNGVVVYSLGHDVNDKLRKLFNVNPVTGE- 303 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTASVF 479 I V LDF+ + Y + + A+D G T V I I D N+ P E ++++ Sbjct: 304 -IVVTGLLDFEVKDIYEIDIQASDKGIAPLTTDKSVTIKIADVNDNEPQIEVTSLSSTIP 362 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 ED+ GTTV ++S +D D GIN ++T SLS I + + + T ++ T L Sbjct: 363 EDSKPGTTVALISVSDLDSGINGRVTCSLSENIPFQLMPSSQEN------TYSLVTTSAL 416 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 DRET++ Y +T+ A+D G P LS V + + DVNDN P F Y +ME+ G S Sbjct: 417 DRETIAHYDITLEAKDAGQPPLSSVKSVTVQISDVNDNSPEFSSSPYAFYVMENNAPGKS 476 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFV----IDPASGVIRTNKALDRESVATHDL 655 + V A+D D G N + Y++ E F I+ +G I K+ D E+ T Sbjct: 477 LFSVSASDKDTGENSAVSYQIWRDGGAENKFTSFININSENGEIYALKSFDFETSKTFQF 536 Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF-------ESDCLTFYISENSPIGTTIGE 708 +A D G+P SS V V++ I D ND+ PV S I N G + + Sbjct: 537 HILATDSGSPSLSSNVTVNVFILDQNDNVPVILYPVSANGSAEGVEEIPRNVNAGHLVTK 596 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 +RA+D D G N + +S++ + + F+L+ G Sbjct: 597 VRAYDADIGYNGWLLFSLQEVSEHSLFALDRYTG 630 Score = 195 bits (475), Expect = 2e-47 Identities = 157/594 (26%), Positives = 270/594 (45%), Gaps = 60/594 (10%) Query: 4 PFCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 P IH ++V+D NDH+P+F Q+ + E G A D D G N+ Y + Sbjct: 115 PLEIHYVTVDVIDVNDHAPMFPEQEKRLEISETVLPGARFQLQAARDPDSGSNSVQTYKL 174 Query: 63 ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122 ++D + DG+ L+ + LDRE + + A D Sbjct: 175 S--------------HTEYFRIEIKDRYE-DGKVPVLILQKPLDREVTKSIKLQLTALDG 219 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 P S TI ++++D NDN P F ++ Y+V+++E+ V I ++ ATD D G Sbjct: 220 GRPPK---SGKMTIIIDVLDINDNAPVFIKEVYSVTLNENTPV--GTTILRVNATDLDEG 274 Query: 183 ANSAIRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239 N + Y++ + + F+++ ++G++ + LD+E Y + I+A D G + Sbjct: 275 QNGVVVYSLGHDVNDKLRKLFNVNPVTGEIVVTGLLDFEVKDIYEIDIQASDKGIAPLTT 334 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 + I I DVNDN P+ + ++ E+ G ++ + D D G+N +T ++++ Sbjct: 335 DKSVTIKIADVNDNEPQIEVTSLSSTIPEDSKPGTTVALISVSDLDSGINGRVTCSLSE- 393 Query: 300 DYTGNVDLPITIDPRSGW----VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355 ++P + P S + T+ LDRET A Y + + A D G PP S+ + Sbjct: 394 ------NIPFQLMPSSQENTYSLVTTSALDRETIAHYDITLEAKDAGQPPLSSVKSVTVQ 447 Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEI-TGGNTRGRF 412 F Y + E+ PG + +++A+D D E++ + Y+I G +F Sbjct: 448 ISDVNDNSPEFSSSPYAFYVMENNAPGKSLFSVSASDKDTGENSAVSYQIWRDGGAENKF 507 Query: 413 S----ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYA 466 + I S+NG I + DF+ + + + ATDSG S ++ V +N I D N+ Sbjct: 508 TSFININSENGE--IYALKSFDFETSKTFQFHILATDSGSPSLSSNVTVNVFILDQNDNV 565 Query: 467 PVF---ENAPYTASVFEDAP----IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAH 519 PV +A +A E+ P G V V A D+D+G N + +SL E+S ++ Sbjct: 566 PVILYPVSANGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQ-EVSEHSL-- 622 Query: 520 HDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 F ++ TG I T + + + L + +D G SLS T V + VV+ Sbjct: 623 ----FALDRYTGQIRTLRSFTETDEAQHKLVILVKDNGNVSLSATATVIVKVVE 672 Score = 161 bits (392), Expect = 2e-37 Identities = 126/429 (29%), Positives = 191/429 (44%), Gaps = 19/429 (4%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 V +++ D N++AP+F + E G + +A D D G N+ TY LS Sbjct: 121 VTVDVIDVNDHAPMFPEQEKRLEISETVLPGARFQLQAARDPDSGSNSVQTYKLSH---T 177 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 E + + + + K LDRE L +TA DGG P S + I V+D+ Sbjct: 178 EYFRIEIKDRYEDGKVPVLILQKPLDREVTKSIKLQLTALDGGRPPKSGKMTIIIDVLDI 237 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDREEGSFVI 632 NDN PVF +++Y+ + E+ VGT++ +V ATD D G NG + Y L D D+ F + Sbjct: 238 NDNAPVFIKEVYSVTLNENTPVGTTILRVNATDLDEGQNGVVVYSLGHDVNDKLRKLFNV 297 Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692 +P +G I LD E +++ A D G P ++ V IKI D+ND+ P E L Sbjct: 298 NPVTGEIVVTGLLDFEVKDIYEIDIQASDKGIAPLTTDKSVTIKIADVNDNEPQIEVTSL 357 Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752 + I E+S GTT+ I D D G N V S+ ++ F L + LVT Sbjct: 358 SSTIPEDSKPGTTVALISVSDLDSGINGRVTCSLS---ENIPFQLMPSSQENTYSLVTTS 414 Query: 753 DLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809 LD E+ Y++ + A PPL + V + ++DVNDN+P F ++ P Sbjct: 415 ALDRETIAH-YDITLEAKDAGQPPLSSVKSVTVQISDVNDNSPEFSSSPYAFYVMENNAP 473 Query: 810 VGPFGRVPAYDADVTDK--LQYRILSGNNA-----NLILLNETTGSMTLSPQLNTNVPKL 862 V A D D + + Y+I A + I +N G + + K Sbjct: 474 GKSLFSVSASDKDTGENSAVSYQIWRDGGAENKFTSFININSENGEIYALKSFDFETSKT 533 Query: 863 ATMEVSVTD 871 + TD Sbjct: 534 FQFHILATD 542 Score = 123 bits (297), Expect = 6e-26 Identities = 100/323 (30%), Positives = 148/323 (45%), Gaps = 15/323 (4%) Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 S+ E+ GT V V+ D+GI+ + I + + + F +N G + Sbjct: 36 SISEEQKDGTAVGNVA---KDLGIDPKTLKERGFRIVSTS---GESMFSVNQNDGVLYVK 89 Query: 537 KLLDRETMSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 LDRE + + + + V + V+DVND+ P+F +Q I E L Sbjct: 90 GKLDRENVCERSTPCLINLKIALENPLEIHYVTVDVIDVNDHAPMFPEQEKRLEISETVL 149 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDR---EEGSFVIDPASGVIRTNKALDRESVAT 652 G A D D G N Y+L + E D V+ K LDRE + Sbjct: 150 PGARFQLQAARDPDSGSNSVQTYKLSHTEYFRIEIKDRYEDGKVPVLILQKPLDREVTKS 209 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 L+ A+DGG PP+S + + I + DIND+ PVF + + ++EN+P+GTTI + A Sbjct: 210 IKLQLTALDGGRPPKSGKMTIIIDVLDINDNAPVFIKEVYSVTLNENTPVGTTILRVNAT 269 Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS- 771 D DEG N VV YS+ G D ++ E+V LD+E + YE+ I+A+ Sbjct: 270 DLDEGQNGVVVYSL-GHDVNDKLRKLFNVNPVTGEIVVTGLLDFE-VKDIYEIDIQASDK 327 Query: 772 --PPLWNDVRVEILVTDVNDNAP 792 PL D V I + DVNDN P Sbjct: 328 GIAPLTTDKSVTIKIADVNDNEP 350 >UniRef50_Q4SNX9 Cluster: Chromosome 15 SCAF14542, whole genome shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 15 SCAF14542, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1074 Score = 221 bits (541), Expect = 2e-55 Identities = 179/618 (28%), Positives = 281/618 (45%), Gaps = 38/618 (6%) Query: 91 RIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQF 150 R+ G L +DRE++ ++T S + V + D NDN P+F Sbjct: 73 RLRESDGQLSIGERIDRERICKHTSQCLIAFDVVSFSKEQFKLIHVEVEVKDINDNTPEF 132 Query: 151 SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS---- 206 K ++ + E+ +V I A D DVG+N Y I + FSID LS Sbjct: 133 PRKESSLEISENTAVGTR--IPLDFAADDDVGSNYIQSYQI---SVNSHFSIDVLSRADG 187 Query: 207 ---GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263 ++ L+K LD E SY L + A DGGSPSR+ TT++ + ++D NDN+P F + F Sbjct: 188 VKYAELVLMKELDRETQASYALELVAVDGGSPSRTGTTRVNVRVKDYNDNSPVFDRNSFS 247 Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323 + E+ P+G ++ + A D DEG+N E+ Y + T + +D +SG + Q Sbjct: 248 VDLPEDAPVGTLLLDLNAEDPDEGLNGEVVYGFGHQVPT-EIRQLFRVDRKSGRLTLESQ 306 Query: 324 LDRETQAKYQLLVTATDGGDPPRSATA--------TXXXXXXXXXXXXXXFMPGQYEVEL 375 +D E++ Y+ V ATD G P A G + Sbjct: 307 IDFESKNTYEFDVQATDLGPNPSPAVCKIVVQVQDVNDNAPEISITPMTSITAGIAYITE 366 Query: 376 AEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435 A +V+ + D+ + ++H + G+ R ++ +I PLD ++ Sbjct: 367 AAARESFVALVSTSDRDSGANGQVHCTLY-GHDHFRLQQAYEDS-FMIVSTSPLDREKIP 424 Query: 436 RYVLTVSATDSGGRSDTAMVQ--INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 Y LTV A D G + Q I +TD N+ APVF Y S+ E+ G + V A Sbjct: 425 EYNLTVVAEDLGSPPFRTITQYTIRLTDENDNAPVFSKPVYEVSMVENNAPGAYIATVVA 484 Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETMSGYLLTVT 552 D D G+N +++Y L+ + + FV ++P +G++ + + E M L +T Sbjct: 485 RDLDTGLNGKVSYKLA---DSYFMGSPISTFVSLDPASGSLYALRSFNYEVMKQLELRIT 541 Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ-QLYTAN----IMEDALVGTSVSQVGATD 607 A D G P LS T +V + +VD NDN P+ Q L+ + + DA G V++V A D Sbjct: 542 ASDAGSPPLSGTANVYVKMVDQNDNAPLITQPPLHNGSAEVLLPRDAPSGYVVTRVEARD 601 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 AD G+N + Y L E F I+ +G I ++AL+ + T + DGG P Sbjct: 602 ADEGMNSAVSYAL--AAGELSVFSINKDTGEIYLSQALNHDVDQTLSVTVTVSDGGRPAL 659 Query: 668 SSTVIVHIKIEDINDSPP 685 +ST +H + I SPP Sbjct: 660 TSTATLHFLV--IEGSPP 675 Score = 212 bits (517), Expect = 1e-52 Identities = 158/523 (30%), Positives = 245/523 (46%), Gaps = 38/523 (7%) Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + ++D+NDN P F +SEN +G I A D D G N +Y ++ + + Sbjct: 120 VEVKDINDNTPEFPRKESSLEISENTAVGTRIPLDFAADDDVGSNYIQSYQISVNSHF-S 178 Query: 305 VDLPITIDP-RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 +D+ D + + +LDRETQA Y L + A DGG P R+ T Sbjct: 179 IDVLSRADGVKYAELVLMKELDRETQASYALELVAVDGGSPSRTGTTRVNVRVKDYNDNS 238 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG-------NTRGRFSITS 416 F + V+L ED P GT ++ L A D DE L+ E+ G R F + Sbjct: 239 PVFDRNSFSVDLPEDAPVGTLLLDLNAEDPDEG--LNGEVVYGFGHQVPTEIRQLFRVDR 296 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPY 474 ++GR +T+ +DF+ + Y V ATD G A+ + + + D N+ AP P Sbjct: 297 KSGR--LTLESQIDFESKNTYEFDVQATDLGPNPSPAVCKIVVQVQDVNDNAPEISITPM 354 Query: 475 T------ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528 T A + E A + V +VS +D D G N Q+ +L ++ F+I Sbjct: 355 TSITAGIAYITEAAARESFVALVSTSDRDSGANGQVHCTLYGHDHFRLQQAYEDSFMI-- 412 Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA 588 ++T+ LDRE + Y LTV A D G P T I + D NDN PVF + +Y Sbjct: 413 ----VSTSP-LDREKIPEYNLTVVAEDLGSPPFRTITQYTIRLTDENDNAPVFSKPVYEV 467 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK---DREEGSFV-IDPASGVIRTNKA 644 +++E+ G ++ V A D D GLNG++ Y+L +FV +DPASG + ++ Sbjct: 468 SMVENNAPGAYIATVVARDLDTGLNGKVSYKLADSYFMGSPISTFVSLDPASGSLYALRS 527 Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL-----TFYISEN 699 + E + +L+ A D G+PP S T V++K+ D ND+ P+ L + + Sbjct: 528 FNYEVMKQLELRITASDAGSPPLSGTANVYVKMVDQNDNAPLITQPPLHNGSAEVLLPRD 587 Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 +P G + + A D DEG N+ V Y++ G+ S FS+ G Sbjct: 588 APSGYVVTRVEARDADEGMNSAVSYALAAGELS-VFSINKDTG 629 Score = 182 bits (443), Expect = 1e-43 Identities = 153/590 (25%), Positives = 257/590 (43%), Gaps = 57/590 (9%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 IH ++ V D ND++P F ++ + E + GT + A D D+G N Y I + Sbjct: 116 IHVEVEVKDINDNTPEFPRKESSLEISENTAVGTRIPLDFAADDDVGSNYIQSYQISV-- 173 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASP 125 + + R DG + L+ LDRE A Y + + A D SP Sbjct: 174 --------------NSHFSIDVLSRADGVKYAELVLMKELDRETQASYALELVAVDGGSP 219 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 + T ++V + D NDN P F +++V + ED V ++ + A D D G N Sbjct: 220 SR---TGTTRVNVRVKDYNDNSPVFDRNSFSVDLPEDAPV--GTLLLDLNAEDPDEGLNG 274 Query: 186 AIRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 + Y + + F +D SG ++L +D+E +Y ++A D G + Sbjct: 275 EVVYGFGHQVPTEIRQLFRVDRKSGRLTLESQIDFESKNTYEFDVQATDLGPNPSPAVCK 334 Query: 243 LLINIRDVNDNAPRF----YTSLFQ--ESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 +++ ++DVNDNAP TS+ ++E + V D D G N ++ T+ Sbjct: 335 IVVQVQDVNDNAPEISITPMTSITAGIAYITEAAARESFVALVSTSDRDSGANGQVHCTL 394 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 D+ L + S + ++ LDRE +Y L V A D G PP Sbjct: 395 YGHDH---FRLQQAYED-SFMIVSTSPLDREKIPEYNLTVVAEDLGSPPFRTITQYTIRL 450 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGR--- 411 F YEV + E+ PG + T+ A D D + ++ Y++ G Sbjct: 451 TDENDNAPVFSKPVYEVSMVENNAPGAYIATVVARDLDTGLNGKVSYKLADSYFMGSPIS 510 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVF 469 ++ G + + +++ ++ L ++A+D+G S TA V + + D N+ AP+ Sbjct: 511 TFVSLDPASGSLYALRSFNYEVMKQLELRITASDAGSPPLSGTANVYVKMVDQNDNAPLI 570 Query: 470 ENAPY---TASVF--EDAPIGTTVLVVSATDSDVGINAQITYSLSS-EISNEAVAHHDQQ 523 P +A V DAP G V V A D+D G+N+ ++Y+L++ E+S Sbjct: 571 TQPPLHNGSAEVLLPRDAPSGYVVTRVEARDADEGMNSAVSYALAAGELS---------V 621 Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 F IN TG I ++ L+ + +TVT DGG P+L+ T + V++ Sbjct: 622 FSINKDTGEIYLSQALNHDVDQTLSVTVTVSDGGRPALTSTATLHFLVIE 671 Score = 177 bits (430), Expect = 5e-42 Identities = 140/473 (29%), Positives = 223/473 (47%), Gaps = 34/473 (7%) Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480 + + + LD + + Y L + A D G R+ T V + + D N+ +PVF+ ++ + E Sbjct: 193 LVLMKELDRETQASYALELVAVDGGSPSRTGTTRVNVRVKDYNDNSPVFDRNSFSVDLPE 252 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 DAP+GT +L ++A D D G+N ++ Y ++ E Q F ++ ++G +T +D Sbjct: 253 DAPVGTLLLDLNAEDPDEGLNGEVVYGFGHQVPTEI----RQLFRVDRKSGRLTLESQID 308 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT------ANIMEDA 594 E+ + Y V A D G + + V DVNDN P T A I E A Sbjct: 309 FESKNTYEFDVQATDLGPNPSPAVCKIVVQVQDVNDNAPEISITPMTSITAGIAYITEAA 368 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654 + V+ V +D D G NG++H L D + + ++ T+ LDRE + ++ Sbjct: 369 ARESFVALVSTSDRDSGANGQVHCTLYGHDHFRLQQAYEDSFMIVSTS-PLDREKIPEYN 427 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 L VA D G+PP + I++ D ND+ PVF + EN+ G I + A D Sbjct: 428 LTVVAEDLGSPPFRTITQYTIRLTDENDNAPVFSKPVYEVSMVENNAPGAYIATVVARDL 487 Query: 715 DEGPNAVVHYSI-----KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 D G N V Y + G S SL+ GS L + +YE K+ EL I A Sbjct: 488 DTGLNGKVSYKLADSYFMGSPISTFVSLDPASGS----LYALRSFNYE-VMKQLELRITA 542 Query: 770 A---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP-VGPFG----RVPAYDA 821 + SPPL V + + D NDNAP++ + + + P P G RV A DA Sbjct: 543 SDAGSPPLSGTANVYVKMVDQNDNAPLITQPPLHNGSAEVLLPRDAPSGYVVTRVEARDA 602 Query: 822 D--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 D + + Y + +G ++ +N+ TG + LS LN +V + ++ V+V+DG Sbjct: 603 DEGMNSAVSYALAAG-ELSVFSINKDTGEIYLSQALNHDVDQTLSVTVTVSDG 654 Score = 157 bits (380), Expect = 5e-36 Identities = 125/456 (27%), Positives = 207/456 (45%), Gaps = 31/456 (6%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS--SEI 512 V++ + D N+ P F + + E+ +GT + + A D DVG N +Y +S S Sbjct: 118 VEVEVKDINDNTPEFPRKESSLEISENTAVGTRIPLDFAADDDVGSNYIQSYQISVNSHF 177 Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572 S + ++ D + + K LDRET + Y L + A DGG PS + TT V + V Sbjct: 178 SIDVLSRAD-----GVKYAELVLMKELDRETQASYALELVAVDGGSPSRTGTTRVNVRVK 232 Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE--GSF 630 D NDN PVF + ++ ++ EDA VGT + + A D D GLNG + Y + E F Sbjct: 233 DYNDNSPVFDRNSFSVDLPEDAPVGTLLLDLNAEDPDEGLNGEVVYGFGHQVPTEIRQLF 292 Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690 +D SG + +D ES T++ A D G P + + ++++D+ND+ P Sbjct: 293 RVDRKSGRLTLESQIDFESKNTYEFDVQATDLGPNPSPAVCKIVVQVQDVNDNAPEISIT 352 Query: 691 CLT------FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD 744 +T YI+E + + + + D D G N VH ++ G D F L+ + D Sbjct: 353 PMTSITAGIAYITEAAARESFVALVSTSDRDSGANGQVHCTLYGHD---HFRLQ-QAYED 408 Query: 745 KAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801 +V+ LD E +Y L + A SPP + I +TD NDNAPV Sbjct: 409 SFMIVSTSPLDREK-IPEYNLTVVAEDLGSPPFRTITQYTIRLTDENDNAPVFSKPVYEV 467 Query: 802 NNYKDCFPVGPFGRVPAYDAD--VTDKLQYRI-----LSGNNANLILLNETTGSMTLSPQ 854 + ++ P V A D D + K+ Y++ + + + L+ +GS+ Sbjct: 468 SMVENNAPGAYIATVVARDLDTGLNGKVSYKLADSYFMGSPISTFVSLDPASGSLYALRS 527 Query: 855 LNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITE 889 N V K + ++ +D G + + V+++ + Sbjct: 528 FNYEVMKQLELRITASDAGSPPLSGTANVYVKMVDQ 563 Score = 78.2 bits (184), Expect = 3e-12 Identities = 76/283 (26%), Positives = 127/283 (44%), Gaps = 15/283 (5%) Query: 635 ASGVIRTNKALDRESVATHDLKA-VAIDGGTPPQSSTVIVHIKIE--DINDSPPVFESDC 691 + G + + +DRE + H + +A D + + ++H+++E DIND+ P F Sbjct: 77 SDGQLSIGERIDRERICKHTSQCLIAFDVVSFSKEQFKLIHVEVEVKDINDNTPEFPRKE 136 Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751 + ISEN+ +GT I A D D G N + Y I + L G AELV M Sbjct: 137 SSLEISENTAVGTRIPLDFAADDDVGSNYIQSYQISVNSHFSIDVLSRADGVKYAELVLM 196 Query: 752 VDLDYESPRK-KYELV-IRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809 +LD E+ ELV + SP RV + V D NDN+PV + +D P Sbjct: 197 KELDRETQASYALELVAVDGGSPSRTGTTRVNVRVKDYNDNSPVFDRNSFSVDLPEDA-P 255 Query: 810 VGP-FGRVPAYDAD--VTDKLQYRI---LSGNNANLILLNETTGSMTLSPQLNTNVPKLA 863 VG + A D D + ++ Y + L ++ +G +TL Q++ Sbjct: 256 VGTLLLDLNAEDPDEGLNGEVVYGFGHQVPTEIRQLFRVDRKSGRLTLESQIDFESKNTY 315 Query: 864 TMEVSVTD-GVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTA 905 +V TD G N A+ ++ V++ +++ N+ + + MT+ Sbjct: 316 EFDVQATDLGPNPSPAVCKIVVQV--QDVNDNAPEISITPMTS 356 >UniRef50_Q3V7B0 Cluster: Protocadherin alpha; n=22; Tetrapoda|Rep: Protocadherin alpha - Macaca fuscata (Japanese macaque) Length = 937 Score = 221 bits (541), Expect = 2e-55 Identities = 173/616 (28%), Positives = 280/616 (45%), Gaps = 31/616 (5%) Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 D+ ++ ++G L + +DRE++ + + + + DR + V + D NDN Sbjct: 73 DLLEVNLQNGILFVNSRIDREELCGRSA--ECSIHLEVIVDRPLQVFHVDVEVKDINDNP 130 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 P F + + E + + A+DAD+G N+ + Y + N + + + Sbjct: 131 PVFPATQKNLFIAESRPLDSRFPLEG--ASDADIGENALLTYRL-SPNEYFSLDVPTSNQ 187 Query: 208 DVS-----LVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLF 262 V L K LD E+ L++ A DGG P + T QLLI + DVNDNAP F +L+ Sbjct: 188 QVKPLGLVLRKPLDREETPELHLLLTATDGGKPELTGTVQLLITVLDVNDNAPVFDRTLY 247 Query: 263 QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322 + ENV IG ++ A D DEG+N ++ Y+ + D + ++ +DP SG + G Sbjct: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFS-SDVSPDIKSKFHMDPVSGAITVIG 306 Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382 +D E +++ V A D G P + T + ++ED PG Sbjct: 307 HMDFEESRAHKIPVEAVDKGFLPLAGHCTVLVEVVDVNDNAPQLTLTSLFLPISEDAQPG 366 Query: 383 TPVVTLTATDADEDNRLHYEITGGNT-RGRFSITS--QNGRGLITVAQPLDFKQERRYVL 439 T V+TL + D D ++ ++T T F + S +N L+ + LD + Y L Sbjct: 367 T-VITLISV-FDRDFGVNGQVTCSLTPHVPFKLVSTFKNYYSLV-LDSVLDRESVSAYEL 423 Query: 440 TVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497 V+A D G S TA V + + D N+ AP F + YT V E+ P G + VSA D+D Sbjct: 424 VVTARDGGSPSLWATASVSVEVADVNDNAPAFTQSEYTVFVKENNPPGCHIFTVSARDAD 483 Query: 498 VGINAQITYSL-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556 NA ++YSL + A++ + ++ ++G + + LD E + V+ARD Sbjct: 484 AQENALVSYSLVERRVGERALSSY---VSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQ-------LYTANIMEDALVGTSVSQVGATDAD 609 GVPSLS +++ V+D NDN PV + + G V++V A DAD Sbjct: 541 GVPSLSSNATLQVFVLDENDNAPVLLAPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 Query: 610 VGLNGRIHYELDP-KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 G N + YE P F + +G I T +AL H L + D G P + Sbjct: 601 SGYNAWLSYEFQPVAVSARIPFRVGLYTGEISTTRALGETDAPRHRLLVLVKDHGEPSLT 660 Query: 669 STVIVHIKIEDINDSP 684 +T V + + + +P Sbjct: 661 ATATVLVSLVESAQAP 676 Score = 204 bits (498), Expect = 3e-50 Identities = 157/549 (28%), Positives = 254/549 (46%), Gaps = 32/549 (5%) Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + ++D+NDN P F + ++E+ P+ A DAD G NA LTY ++ +Y + Sbjct: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYF-S 179 Query: 305 VDLPITIDP-RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 +D+P + + + LDRE + LL+TATDGG P + T Sbjct: 180 LDVPTSNQQVKPLGLVLRKPLDREETPELHLLLTATDGGKPELTGTVQLLITVLDVNDNA 239 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGG---NTRGRFSITSQN 418 F Y V+L E+ GT V+ A+D DE + + Y + + + +F + + Sbjct: 240 PVFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPVS 299 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTA 476 G ITV +DF++ R + + V A D G + V + + D N+ AP Sbjct: 300 GA--ITVIGHMDFEESRAHKIPVEAVDKGFLPLAGHCTVLVEVVDVNDNAPQLTLTSLFL 357 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 + EDA GT + ++S D D G+N Q+T SL+ + + V+ + ++ + Sbjct: 358 PISEDAQPGTVITLISVFDRDFGVNGQVTCSLTPHVPFKLVSTFKNYY-------SLVLD 410 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 +LDRE++S Y L VTARDGG PSL T V + V DVNDN P F Q YT + E+ Sbjct: 411 SVLDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFTQSEYTVFVKENNPP 470 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPK---DREEGSFV-IDPASGVIRTNKALDRESVAT 652 G + V A DAD N + Y L + +R S+V + SG + + LD E + Sbjct: 471 GCHIFTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELEL 530 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES-------DCLTFYISENSPIGTT 705 + A D G P SS + + + D ND+ PV + ++ + + G Sbjct: 531 LQFQVSARDAGVPSLSSNATLQVFVLDENDNAPVLLAPRVGGIGGAVSELVPRSVGAGHV 590 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDL-DYESPRKKYE 764 + ++RA D D G NA + Y + + S + R G E+ T L + ++PR + Sbjct: 591 VAKVRAVDADSGYNAWLSYEFQ--PVAVSARIPFRVGLYTGEISTTRALGETDAPRHRLL 648 Query: 765 LVIRAASPP 773 ++++ P Sbjct: 649 VLVKDHGEP 657 Score = 187 bits (456), Expect = 3e-45 Identities = 137/440 (31%), Positives = 220/440 (50%), Gaps = 18/440 (4%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGR--- 420 F Q + +AE P + A+DAD E+ L Y ++ N + + N + Sbjct: 133 FPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSP-NEYFSLDVPTSNQQVKP 191 Query: 421 -GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTAS 477 GL+ + +PLD ++ L ++ATD G T VQ+ IT D N+ APVF+ YT Sbjct: 192 LGLV-LRKPLDREETPELHLLLTATDGGKPELTGTVQLLITVLDVNDNAPVFDRTLYTVK 250 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 + E+ IGT V+ +A+D D G+N I YS SS++S + + +F ++P +GAIT Sbjct: 251 LPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKS----KFHMDPVSGAITVIG 306 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 +D E + + V A D G L+ V + VVDVNDN P I EDA G Sbjct: 307 HMDFEESRAHKIPVEAVDKGFLPLAGHCTVLVEVVDVNDNAPQLTLTSLFLPISEDAQPG 366 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 T ++ + D D G+NG++ L P + ++ + LDRESV+ ++L Sbjct: 367 TVITLISVFDRDFGVNGQVTCSLTPHVPFKLVSTFKNYYSLV-LDSVLDRESVSAYELVV 425 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A DGG+P +T V +++ D+ND+ P F T ++ EN+P G I + A D D Sbjct: 426 TARDGGSPSLWATASVSVEVADVNDNAPAFTQSEYTVFVKENNPPGCHIFTVSARDADAQ 485 Query: 718 PNAVVHYS-IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIRAAS-PPL 774 NA+V YS ++ + S ++ ++ + LD+E ++++ R A P L Sbjct: 486 ENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPSL 545 Query: 775 WNDVRVEILVTDVNDNAPVM 794 ++ +++ V D NDNAPV+ Sbjct: 546 SSNATLQVFVLDENDNAPVL 565 Score = 169 bits (412), Expect = 7e-40 Identities = 141/449 (31%), Positives = 208/449 (46%), Gaps = 23/449 (5%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS-SEIS 513 V + + D N+ PVF + E P+ + + A+D+D+G NA +TY LS +E Sbjct: 119 VDVEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYF 178 Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 + V +QQ + P + K LDRE L +TA DGG P L+ T + I+V+D Sbjct: 179 SLDVPTSNQQ--VKPL--GLVLRKPLDREETPELHLLLTATDGGKPELTGTVQLLITVLD 234 Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDREEGSFV 631 VNDN PVF + LYT + E+ +GT V A+D D GLNG I Y D + F Sbjct: 235 VNDNAPVFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFH 294 Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691 +DP SG I +D E H + A+D G P + V +++ D+ND+ P Sbjct: 295 MDPVSGAITVIGHMDFEESRAHKIPVEAVDKGFLPLAGHCTVLVEVVDVNDNAPQLTLTS 354 Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751 L ISE++ GT I I D D G N V S+ F L + + + ++ Sbjct: 355 LFLPISEDAQPGTVITLISVFDRDFGVNGQVTCSLT---PHVPFKLVSTFKNYYSLVLDS 411 Query: 752 VDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCF 808 V LD ES YELV+ A SP LW V + V DVNDNAP + ++ Sbjct: 412 V-LDRESV-SAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFTQSEYTVFVKENNP 469 Query: 809 PVGPFGRVPAYDADVTDK--LQYRILS---GNNA--NLILLNETTGSMTLSPQLNTNVPK 861 P V A DAD + + Y ++ G A + + ++ +G + L+ + Sbjct: 470 PGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELE 529 Query: 862 LATMEVSVTD-GVNEIKAMMQLSVRLITE 889 L +VS D GV + + L V ++ E Sbjct: 530 LLQFQVSARDAGVPSLSSNATLQVFVLDE 558 Score = 146 bits (354), Expect = 8e-33 Identities = 108/345 (31%), Positives = 164/345 (47%), Gaps = 28/345 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I VLD ND++PVF+ Y + E S GT V+ A+D D G N ++ Y+ + + Sbjct: 230 ITVLDVNDNAPVFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSF----SSDV 285 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +P+ ++ F +D SGA+ +D E+ + + V+A D+ L Sbjct: 286 SPD------------IKSKFHMDPVSGAITVIGHMDFEESRAHKIPVEAVDKGFL---PL 330 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + T+ V ++D NDN PQ + + + + ED VI I D D G N + + Sbjct: 331 AGHCTVLVEVVDVNDNAPQLTLTSLFLPISED--AQPGTVITLISVFDRDFGVNGQVTCS 388 Query: 191 IIGGNTQMQFS-IDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 + + F + + SLV LD E V +Y LV+ A+DGGSPS T + + + Sbjct: 389 L---TPHVPFKLVSTFKNYYSLVLDSVLDRESVSAYELVVTARDGGSPSLWATASVSVEV 445 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN-VD 306 DVNDNAP F S + V EN P G I V A DAD NA ++Y++ ++ + Sbjct: 446 ADVNDNAPAFTQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALS 505 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 +++ SG VY LD E Q V+A D G P S+ AT Sbjct: 506 SYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPSLSSNAT 550 Score = 66.1 bits (154), Expect = 1e-08 Identities = 55/212 (25%), Positives = 101/212 (47%), Gaps = 11/212 (5%) Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV-IDPASGVIRTNKALDR 647 ++ E+A GT V ++ A D + L+ + + G + ++ +G++ N +DR Sbjct: 34 SVPEEAKHGTFVGRI-AQDLGLELSELVPRLFRAVCKFRGDLLEVNLQNGILFVNSRIDR 92 Query: 648 ESVATHDLK-AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706 E + + ++ ++ V ++++DIND+PPVF + +I+E+ P+ + Sbjct: 93 EELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPPVFPATQKNLFIAESRPLDSRF 152 Query: 707 GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE---LVTMVDLDYESPRKKY 763 A D D G NA++ Y + + FSL+ + + + LV LD E + + Sbjct: 153 PLEGASDADIGENALLTYRL---SPNEYFSLDVPTSNQQVKPLGLVLRKPLDREETPELH 209 Query: 764 ELVIR--AASPPLWNDVRVEILVTDVNDNAPV 793 L+ P L V++ I V DVNDNAPV Sbjct: 210 LLLTATDGGKPELTGTVQLLITVLDVNDNAPV 241 >UniRef50_UPI0000F2DF7E Cluster: PREDICTED: similar to protocadherin 8; n=1; Monodelphis domestica|Rep: PREDICTED: similar to protocadherin 8 - Monodelphis domestica Length = 955 Score = 220 bits (538), Expect = 4e-55 Identities = 168/552 (30%), Positives = 260/552 (47%), Gaps = 45/552 (8%) Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295 S S + + +RD+ND++PRF S VSE+ +G I A D D G NA + Sbjct: 176 SFSQLIHVEVEVRDINDHSPRFPRSQILVEVSESAAVGTRIPLEVAVDEDVGSNALQSLR 235 Query: 296 MTDKDYTGNVDLPITID-PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354 + + V+L D ++ + +LDRE+QA Y L + A DGGDPPRSATA Sbjct: 236 LVEPHSFFRVELQTRADGAKNADLLLLQELDRESQANYSLELVAQDGGDPPRSATAVLSV 295 Query: 355 XXXXXXXXXXXFMPGQY-EVELAEDEPPGTPVVTLTATDADEDNRLHYEIT-GGNT--RG 410 F G + EVE++ED P G+ ++ + ATD DE + GG T Sbjct: 296 RVLDANDHSPVFPLGSFIEVEVSEDSPEGSLLLDIDATDPDEGPSGDVVFSFGGRTPPEA 355 Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS--GGRSDTAMVQINITDANNYAPV 468 + G +T+ +PLD++Q+ Y L V A D G R T V ++I D N+ APV Sbjct: 356 QLPFHLDPRSGHLTLTRPLDYEQKETYELDVMAQDQGPGSRVSTCKVIVHILDVNDNAPV 415 Query: 469 FENAPY-----TASVFED---API------------GTTVLVV---SATDSDVGINAQIT 505 P TAS + AP+ G + ++ +A +S V + + + Sbjct: 416 ITIIPLVMAVNTASDYSSSFAAPVSASWEEPGGPQSGVALSLIPEGAAQESLVALVSTLD 475 Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGA---ITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 S + + F + P + T LDRE + Y LT+ A+D G P LS Sbjct: 476 RDSDSNGQVHCALYGHEHFRLQPAYAGSYLVLTTTPLDRERIPEYNLTLVAQDLGSPPLS 535 Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE-LD 621 + V D NDN P+F + +Y +++E+ G ++ V A D D+G NG++ Y L+ Sbjct: 536 TMRPYTVRVADENDNAPLFARPVYEVSVLENNFPGAYLTTVVARDPDLGRNGKVTYRLLE 595 Query: 622 PKDREEGSFV-----IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676 K+ ++ V +D SGV+R + DRE++A ++ A DGG+P Q +V + Sbjct: 596 TKEGQDRDLVSAYVSVDSDSGVLRARRRFDREALAELEVALEARDGGSPSQWGQTVVRLV 655 Query: 677 IEDIND-SP----PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD- 730 +ED ND +P P+ + + P G + ++A D DEGPNA + YS+ D Sbjct: 656 VEDQNDHAPEVIFPLLSNGSALVPLPRGVPPGFLVTRVQARDEDEGPNAELTYSLTHSDG 715 Query: 731 DSNSFSLETRQG 742 D + +L G Sbjct: 716 DPGALALHPHTG 727 Score = 184 bits (448), Expect = 3e-44 Identities = 177/616 (28%), Positives = 268/616 (43%), Gaps = 76/616 (12%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 IH ++ V D NDHSP F Q V E A+ GT + A D+D+G NA L + Sbjct: 181 IHVEVEVRDINDHSPRFPRSQILVEVSESAAVGTRIPLEVAVDEDVGSNA-------LQS 233 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGA-LLTRASLDREKVARYTVLVKATDQASP 125 + P V+ R DG A LL LDRE A Y++ + A D P Sbjct: 234 LRLVEPHS--------FFRVELQTRADGAKNADLLLLQELDRESQANYSLELVAQDGGDP 285 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYT-VSVDEDISVTDNPVIAKIKATDADVGAN 184 S+TA + V ++D ND+ P F ++ V V ED + ++ I ATD D G + Sbjct: 286 PR---SATAVLSVRVLDANDHSPVFPLGSFIEVEVSEDSP--EGSLLLDIDATDPDEGPS 340 Query: 185 SAIRYAIIGGNT----QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240 + ++ GG T Q+ F +D SG ++L + LDYEQ +Y L + AQD G SR +T Sbjct: 341 GDVVFSF-GGRTPPEAQLPFHLDPRSGHLTLTRPLDYEQKETYELDVMAQDQGPGSRVST 399 Query: 241 TQLLINIRDVNDNAPRF--------------YTSLFQESVSEN------VPIGYSIVRVQ 280 +++++I DVNDNAP Y+S F VS + G ++ + Sbjct: 400 CKVIVHILDVNDNAPVITIIPLVMAVNTASDYSSSFAAPVSASWEEPGGPQSGVALSLIP 459 Query: 281 AYDADEGVNAELTYTMTDKDYTGNVDLPI------TIDPR---SGWVYTSGQLDRETQAK 331 A E + A ++ D D G V + + P S V T+ LDRE + Sbjct: 460 EGAAQESLVALVSTLDRDSDSNGQVHCALYGHEHFRLQPAYAGSYLVLTTTPLDRERIPE 519 Query: 332 YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTAT 391 Y L + A D G PP S F YEV + E+ PG + T+ A Sbjct: 520 YNLTLVAQDLGSPPLSTMRPYTVRVADENDNAPLFARPVYEVSVLENNFPGAYLTTVVAR 579 Query: 392 DAD--EDNRLHY---EITGGNTRGRFS--ITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444 D D + ++ Y E G R S ++ + G++ + D + + + A Sbjct: 580 DPDLGRNGKVTYRLLETKEGQDRDLVSAYVSVDSDSGVLRARRRFDREALAELEVALEAR 639 Query: 445 DSGGRSD--TAMVQINITDANNYA-----PVFENAPYTASVFEDAPIGTTVLVVSATDSD 497 D G S +V++ + D N++A P+ N + P G V V A D D Sbjct: 640 DGGSPSQWGQTVVRLVVEDQNDHAPEVIFPLLSNGSALVPLPRGVPPGFLVTRVQARDED 699 Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG 557 G NA++TYSL+ + ++P TG ++ + L + L VT +D G Sbjct: 700 EGPNAELTYSLTHSDGDPGA------LALHPHTGELSLRRQLSPWPIDPLTLVVTVQDNG 753 Query: 558 VPSLSDTTDVEISVVD 573 PSLS TT + +S+ + Sbjct: 754 RPSLSCTTTLMLSLAE 769 Score = 121 bits (292), Expect = 3e-25 Identities = 89/248 (35%), Positives = 125/248 (50%), Gaps = 16/248 (6%) Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617 V S S VE+ V D+ND+ P F + + E A VGT + A D DVG N Sbjct: 174 VVSFSQLIHVEVEVRDINDHSPRFPRSQILVEVSESAAVGTRIPLEVAVDEDVGSNALQS 233 Query: 618 YEL-DPKD--REEGSFVIDPASGV-IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673 L +P R E D A + + LDRES A + L+ VA DGG PP+S+T ++ Sbjct: 234 LRLVEPHSFFRVELQTRADGAKNADLLLLQELDRESQANYSLELVAQDGGDPPRSATAVL 293 Query: 674 HIKIEDINDSPPVFE-SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732 +++ D ND PVF + +SE+SP G+ + +I A DPDEGP+ V +S G Sbjct: 294 SVRVLDANDHSPVFPLGSFIEVEVSEDSPEGSLLLDIDATDPDEGPSGDVVFSFGGRTPP 353 Query: 733 NS---FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDV---RVEILVTD 786 + F L+ R G L LDYE ++ YEL + A + V +V + + D Sbjct: 354 EAQLPFHLDPRSG----HLTLTRPLDYEQ-KETYELDVMAQDQGPGSRVSTCKVIVHILD 408 Query: 787 VNDNAPVM 794 VNDNAPV+ Sbjct: 409 VNDNAPVI 416 Score = 117 bits (281), Expect = 5e-24 Identities = 168/655 (25%), Positives = 268/655 (40%), Gaps = 73/655 (11%) Query: 377 EDEPPGTPVVTLTA-TDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP-LDFKQE 434 E+E PGT + L+A T AD + I G +TV + +D +Q Sbjct: 102 EEEIPGTVIGVLSAHTRADSPGMVPRNFRLMKQFNTSLIRLSEDDGQLTVGENGIDREQL 161 Query: 435 RRYVLTVSAT-DSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 + + T D S V++ + D N+++P F + V E A +GT + + A Sbjct: 162 CQQSQQCTLTFDVVSFSQLIHVEVEVRDINDHSPRFPRSQILVEVSESAAVGTRIPLEVA 221 Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553 D DVG NA + L S V Q + + + LDRE+ + Y L + A Sbjct: 222 VDEDVGSNALQSLRLVEPHSFFRVEL--QTRADGAKNADLLLLQELDRESQANYSLELVA 279 Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFK-QQLYTANIMEDALVGTSVSQVGATDADVGL 612 +DGG P S T + + V+D ND+ PVF + ED+ G+ + + ATD D G Sbjct: 280 QDGGDPPRSATAVLSVRVLDANDHSPVFPLGSFIEVEVSEDSPEGSLLLDIDATDPDEGP 339 Query: 613 NGRIHYELDPKDREEGS--FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST 670 +G + + + E F +DP SG + + LD E T++L +A D G + ST Sbjct: 340 SGDVVFSFGGRTPPEAQLPFHLDPRSGHLTLTRPLDYEQKETYELDVMAQDQGPGSRVST 399 Query: 671 VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE--GPNAVVHYSI-- 726 V + I D+ND+ PV L ++ S ++ + +E GP + V S+ Sbjct: 400 CKVIVHILDVNDNAPVITIIPLVMAVNTASDYSSSFAAPVSASWEEPGGPQSGVALSLIP 459 Query: 727 KGG---------------DDSNS-----------FSLETRQGSDKAELVTMVDLDYES-P 759 +G DSN F L+ L T LD E P Sbjct: 460 EGAAQESLVALVSTLDRDSDSNGQVHCALYGHEHFRLQPAYAGSYLVLTT-TPLDRERIP 518 Query: 760 RKKYELVIR-AASPPLWNDVRVEILVTDVNDNAPV----MKDFQIIFNNYKDCFPVGPFG 814 LV + SPPL + V D NDNAP+ + + ++ NN+ + Sbjct: 519 EYNLTLVAQDLGSPPLSTMRPYTVRVADENDNAPLFARPVYEVSVLENNFPGAYLTTVVA 578 Query: 815 RVPAYDADVTDKLQYRIL---SGNNANLI--LLNETTGSMTLSPQLNTNVPKLATMEVSV 869 R P D K+ YR+L G + +L+ ++ + S L + + LA +EV++ Sbjct: 579 RDP--DLGRNGKVTYRLLETKEGQDRDLVSAYVSVDSDSGVLRARRRFDREALAELEVAL 636 Query: 870 --TDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCP 927 DG Q VRL+ E+ ND A + + PLL +G +A++P P Sbjct: 637 EARDG-GSPSQWGQTVVRLVVEDQ---------ND-HAPEVIFPLLS---NG-SALVPLP 681 Query: 928 K---ENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERV 979 + + VQ + G +++S D + G PH LR ++ Sbjct: 682 RGVPPGFLVTRVQARDEDEGPNAELTYSLTHSDGDPGALA-LHPHTGELSLRRQL 735 Score = 106 bits (254), Expect = 1e-20 Identities = 77/242 (31%), Positives = 120/242 (49%), Gaps = 11/242 (4%) Query: 116 LVKATDQASPVSDRLSSTATIHVNII--DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK 173 L + + Q + D +S + IHV + D ND+ P+F V V E +V I Sbjct: 161 LCQQSQQCTLTFDVVSFSQLIHVEVEVRDINDHSPRFPRSQILVEVSESAAVGTR--IPL 218 Query: 174 IKATDADVGANSAIRYAIIGGNT----QMQFSIDSL-SGDVSLVKTLDYEQVRSYRLVIR 228 A D DVG+N+ ++ ++ ++Q D + D+ L++ LD E +Y L + Sbjct: 219 EVAVDEDVGSNALQSLRLVEPHSFFRVELQTRADGAKNADLLLLQELDRESQANYSLELV 278 Query: 229 AQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE-SVSENVPIGYSIVRVQAYDADEG 287 AQDGG P RS T L + + D ND++P F F E VSE+ P G ++ + A D DEG Sbjct: 279 AQDGGDPPRSATAVLSVRVLDANDHSPVFPLGSFIEVEVSEDSPEGSLLLDIDATDPDEG 338 Query: 288 VNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRS 347 + ++ ++ + LP +DPRSG + + LD E + Y+L V A D G R Sbjct: 339 PSGDVVFSFGGRT-PPEAQLPFHLDPRSGHLTLTRPLDYEQKETYELDVMAQDQGPGSRV 397 Query: 348 AT 349 +T Sbjct: 398 ST 399 Score = 104 bits (250), Expect = 3e-20 Identities = 123/487 (25%), Positives = 196/487 (40%), Gaps = 42/487 (8%) Query: 11 INVLDCNDHSPVFEMQQY-EASVREGASSGTTVLTLKATDQDIGKNAEVEYTI------E 63 + VLD NDHSPVF + + E V E + G+ +L + ATD D G + +V ++ E Sbjct: 295 VRVLDANDHSPVFPLGSFIEVEVSEDSPEGSLLLDIDATDPDEGPSGDVVFSFGGRTPPE 354 Query: 64 LVTADTLNPEDAXXXXXXXXXXVQ------DVFRIDGRSGALLTRAS-----LDREKVAR 112 L+P Q DV D G+ ++ LD A Sbjct: 355 AQLPFHLDPRSGHLTLTRPLDYEQKETYELDVMAQDQGPGSRVSTCKVIVHILDVNDNAP 414 Query: 113 YTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIA 172 ++ + SD SS A V+ + PQ +S+ + + ++ ++A Sbjct: 415 VITIIPLVMAVNTASDYSSSFAA-PVSASWEEPGGPQSG---VALSLIPEGAAQES-LVA 469 Query: 173 KIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRA 229 + D D +N + A+ G F + LV T LD E++ Y L + A Sbjct: 470 LVSTLDRDSDSNGQVHCALYGHE---HFRLQPAYAGSYLVLTTTPLDRERIPEYNLTLVA 526 Query: 230 QDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN 289 QD GSP S + + D NDNAP F +++ SV EN G + V A D D G N Sbjct: 527 QDLGSPPLSTMRPYTVRVADENDNAPLFARPVYEVSVLENNFPGAYLTTVVARDPDLGRN 586 Query: 290 AELTYTMTDKDYTGNVDLP---ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR 346 ++TY + + + DL +++D SG + + DRE A+ ++ + A DGG P + Sbjct: 587 GKVTYRLLETKEGQDRDLVSAYVSVDSDSGVLRARRRFDREALAELEVALEARDGGSPSQ 646 Query: 347 -SATATXXXXXXXXXXXXXXFMP----GQYEVELAEDEPPGTPVVTLTATDADE--DNRL 399 T P G V L PPG V + A D DE + L Sbjct: 647 WGQTVVRLVVEDQNDHAPEVIFPLLSNGSALVPLPRGVPPGFLVTRVQARDEDEGPNAEL 706 Query: 400 HYEIT-GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN 458 Y +T G ++ G +++ + L L V+ D+G S + + Sbjct: 707 TYSLTHSDGDPGALALHPHTGE--LSLRRQLSPWPIDPLTLVVTVQDNGRPSLSCTTTLM 764 Query: 459 ITDANNY 465 ++ A +Y Sbjct: 765 LSLAESY 771 Score = 98.7 bits (235), Expect = 2e-18 Identities = 78/302 (25%), Positives = 129/302 (42%), Gaps = 9/302 (2%) Query: 385 VVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444 +V+ D+D + ++H + G + R + G L+ PLD ++ Y LT+ A Sbjct: 470 LVSTLDRDSDSNGQVHCALYG-HEHFRLQ-PAYAGSYLVLTTTPLDRERIPEYNLTLVAQ 527 Query: 445 DSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502 D G + M + + D N+ AP+F Y SV E+ G + V A D D+G N Sbjct: 528 DLGSPPLSTMRPYTVRVADENDNAPLFARPVYEVSVLENNFPGAYLTTVVARDPDLGRNG 587 Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 ++TY L + ++ +G + + DRE ++ + + ARDGG PS Sbjct: 588 KVTYRLLETKEGQDRDLVSAYVSVDSDSGVLRARRRFDREALAELEVALEARDGGSPSQW 647 Query: 563 DTTDVEISVVDVNDNEP-VFKQQLYTANIM----EDALVGTSVSQVGATDADVGLNGRIH 617 T V + V D ND+ P V L + + G V++V A D D G N + Sbjct: 648 GQTVVRLVVEDQNDHAPEVIFPLLSNGSALVPLPRGVPPGFLVTRVQARDEDEGPNAELT 707 Query: 618 YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 Y L D + G+ + P +G + + L + L D G P S T + + + Sbjct: 708 YSLTHSDGDPGALALHPHTGELSLRRQLSPWPIDPLTLVVTVQDNGRPSLSCTTTLMLSL 767 Query: 678 ED 679 + Sbjct: 768 AE 769 Score = 84.6 bits (200), Expect = 4e-14 Identities = 96/343 (27%), Positives = 150/343 (43%), Gaps = 25/343 (7%) Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM-EDALVGTSVSQVGAT 606 ++T+ V + SD + + V + EP Q +++ E A + V+ V Sbjct: 415 VITIIPLVMAVNTASDYSSSFAAPVSASWEEPGGPQSGVALSLIPEGAAQESLVALVSTL 474 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPA---SGVIRTNKALDRESVATHDLKAVAIDGG 663 D D NG++H L + F + PA S ++ T LDRE + ++L VA D G Sbjct: 475 DRDSDSNGQVHCALYGHEH----FRLQPAYAGSYLVLTTTPLDRERIPEYNLTLVAQDLG 530 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 +PP S+ +++ D ND+ P+F + EN+ G + + A DPD G N V Sbjct: 531 SPPLSTMRPYTVRVADENDNAPLFARPVYEVSVLENNFPGAYLTTVVARDPDLGRNGKVT 590 Query: 724 YSI---KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWND 777 Y + K G D + S SD L D E+ + E+ + A SP W Sbjct: 591 YRLLETKEGQDRDLVSAYVSVDSDSGVLRARRRFDREA-LAELEVALEARDGGSPSQWGQ 649 Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDC-FPVG-PFG----RVPAYDAD--VTDKLQY 829 V ++V D ND+AP + F ++ N P G P G RV A D D +L Y Sbjct: 650 TVVRLVVEDQNDHAPEV-IFPLLSNGSALVPLPRGVPPGFLVTRVQARDEDEGPNAELTY 708 Query: 830 RIL-SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + S + + L+ TG ++L QL+ T+ V+V D Sbjct: 709 SLTHSDGDPGALALHPHTGELSLRRQLSPWPIDPLTLVVTVQD 751 >UniRef50_UPI000069E759 Cluster: UPI000069E759 related cluster; n=4; Xenopus tropicalis|Rep: UPI000069E759 UniRef100 entry - Xenopus tropicalis Length = 818 Score = 220 bits (538), Expect = 4e-55 Identities = 181/648 (27%), Positives = 293/648 (45%), Gaps = 27/648 (4%) Query: 90 FRIDGRSGALLTRA-SLDREKVARYTVLVKATDQ--ASPVSDRLSSTATIHVNIIDDNDN 146 F +D ++G L T A LDRE + L + + A S S A I + I+D ND+ Sbjct: 65 FHLDKQTGDLYTTAFKLDREHLCPQDTLNQCFVEIDAFVSSQEHSEIAKIKIFILDINDH 124 Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206 P F+++ T+SV ED +V I A+D D G NS + Y + + +S Sbjct: 125 APFFTDRIITISVQEDTAVGTIFSIDH-SASDPDAGQNSILLYHLNSIDNVFTLGNNSQL 183 Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266 ++L + LD+E Y + + A D G P S + +++ I DVNDN P F TS + Sbjct: 184 LSLTLQQPLDHESKSEYYMDLIASDKGQPPLSGSALIIVQITDVNDNCPVFLTSNMFIIL 243 Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326 N + ++ +++A D D G N+ + Y +++ + L ++ +G + + + Sbjct: 244 QRNSSVNSTVTQLEAVDEDTGENSIIQYVYSNRVPAESKKL-FHLESMTGILRLAAPIPE 302 Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF----MPGQYEVELAEDEPPG 382 ++ ++L V A G P AT F G+ V + ED P Sbjct: 303 DSPNNHKLTVLAIGPGCAPAVATVKLAIQELKRKEPRMEFRVIGAQGEEGVSVKEDVPIN 362 Query: 383 TPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV- 441 T + L D D I G + L+ + LDF+ E++Y + V Sbjct: 363 TIIAILEIKDTDYSILRPVYINGTIPFALKVSENSPDTYLLLTSGILDFELEQKYTIQVL 422 Query: 442 -SATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 +AT A + + + D N+ AP F + SV E+ G +L +SA D D G Sbjct: 423 GNATFDNLIVYQASLNVKLEDVNDNAPQFPQSVLEVSVEENNSPGAVILELSAFDRDSGS 482 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560 N I YS +E+ E F I+ G +T + DRE + Y + V A D G P+ Sbjct: 483 NGIIDYSFGAELPME--------FFIDASHGILTASVSFDREQKTSYTVIVLASDHGSPA 534 Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620 + + V I+++D NDN P+F +T ++ E+ +V + TDAD GLNG I + Sbjct: 535 QNGSCTVIITILDQNDNMPIFLTNEFTFSVPENLSRHGTVGIINVTDADSGLNGEISLSM 594 Query: 621 DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680 F +D +I LD ES ++L A D G PP SSTV V+I + D+ Sbjct: 595 ---LNTTMPFSVD--KNIILLEGYLDYESEYKYELWIEAHDKGNPPLSSTVKVNIMVLDM 649 Query: 681 NDSPPVF---ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 ND+ P+ +S+ + ++ G+++ ++ A D D G N + YS Sbjct: 650 NDNAPLILLPDSNFSYVLVPPDTLKGSSVTKVHAVDYDAGMNGAIQYS 697 Score = 181 bits (440), Expect = 3e-43 Identities = 177/648 (27%), Positives = 285/648 (43%), Gaps = 54/648 (8%) Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIG--YSIVRVQAYDADEGVNAE 291 S S ++ I I D+ND+AP F + SV E+ +G +SI A D D G N+ Sbjct: 105 SQEHSEIAKIKIFILDINDHAPFFTDRIITISVQEDTAVGTIFSIDH-SASDPDAGQNSI 163 Query: 292 LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGGDPPRSAT 349 L Y + ++D T+ S + + Q LD E++++Y + + A+D G PP S + Sbjct: 164 LLY------HLNSIDNVFTLGNNSQLLSLTLQQPLDHESKSEYYMDLIASDKGQPPLSGS 217 Query: 350 ATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITG-- 405 A F+ + L + + V L A D D E++ + Y + Sbjct: 218 ALIIVQITDVNDNCPVFLTSNMFIILQRNSSVNSTVTQLEAVDEDTGENSIIQYVYSNRV 277 Query: 406 -GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANN 464 ++ F + S G ++ +A P+ + LTV A G A V++ I + Sbjct: 278 PAESKKLFHLESMTG--ILRLAAPIPEDSPNNHKLTVLAIGPGCAPAVATVKLAIQELKR 335 Query: 465 YAPVFENAPYTA------SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518 P E A SV ED PI T + ++ D+D I L N + Sbjct: 336 KEPRMEFRVIGAQGEEGVSVKEDVPINTIIAILEIKDTDYSI-------LRPVYINGTIP 388 Query: 519 HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578 + +P T + T+ +LD E Y + V + + + + DVNDN Sbjct: 389 FALKVSENSPDTYLLLTSGILDFELEQKYTIQVLGNATFDNLIVYQASLNVKLEDVNDNA 448 Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638 P F Q + ++ E+ G + ++ A D D G NG I Y + E F ID + G+ Sbjct: 449 PQFPQSVLEVSVEENNSPGAVILELSAFDRDSGSNGIIDYSFGAELPME--FFIDASHGI 506 Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698 + + + DRE ++ + +A D G+P Q+ + V I I D ND+ P+F ++ TF + E Sbjct: 507 LTASVSFDREQKTSYTVIVLASDHGSPAQNGSCTVIITILDQNDNMPIFLTNEFTFSVPE 566 Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758 N T+G I D D G N + S+ + + FS+ DK ++ LDYES Sbjct: 567 NLSRHGTVGIINVTDADSGLNGEISLSML--NTTMPFSV------DKNIILLEGYLDYES 618 Query: 759 PRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVM----KDFQIIFNNYKDCFPVG 811 KYEL I A +PPL + V+V I+V D+NDNAP++ +F + D Sbjct: 619 -EYKYELWIEAHDKGNPPLSSTVKVNIMVLDMNDNAPLILLPDSNFSYVLVP-PDTLKGS 676 Query: 812 PFGRVPA--YDADVTDKLQYRILS--GNNANLILLNETTGSMTLSPQL 855 +V A YDA + +QY G +L ++ TG++TL + Sbjct: 677 SVTKVHAVDYDAGMNGAIQYSGFGELGPLGDLFTIDNITGNITLKESI 724 Score = 177 bits (430), Expect = 5e-42 Identities = 184/687 (26%), Positives = 299/687 (43%), Gaps = 74/687 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTV-LTLKATDQDIGKNAEVEYTIELVTAD 68 +I +LD NDH+P F + SV+E + GT + A+D D G+N+ + Y + Sbjct: 115 KIFILDINDHAPFFTDRIITISVQEDTAVGTIFSIDHSASDPDAGQNSILLYHLN----- 169 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LT-RASLDREKVARYTVLVKATDQASPV 126 + +VF + S L LT + LD E + Y + + A+D+ P Sbjct: 170 ----------------SIDNVFTLGNNSQLLSLTLQQPLDHESKSEYYMDLIASDKGQPP 213 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 LS +A I V I D NDN P F + + + SV N + +++A D D G NS Sbjct: 214 ---LSGSALIIVQITDVNDNCPVFLTSNMFIILQRNSSV--NSTVTQLEAVDEDTGENSI 268 Query: 187 IRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 I+Y + ++ F ++S++G + L + + +++L + A G T +L Sbjct: 269 IQYVYSNRVPAESKKLFHLESMTGILRLAAPIPEDSPNNHKLTVLAIGPGCAPAVATVKL 328 Query: 244 LINIRDVNDNAPRFYTSLF----QESVS--ENVPIGYSIVRVQAYDADEGVNAELTYTMT 297 I +++ PR + +E VS E+VPI I ++ D D Y++ Sbjct: 329 AI--QELKRKEPRMEFRVIGAQGEEGVSVKEDVPINTIIAILEIKDTD--------YSIL 378 Query: 298 DKDY-TGNVDLPITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353 Y G + + + S Y TSG LD E + KY + V D A+ Sbjct: 379 RPVYINGTIPFALKVSENSPDTYLLLTSGILDFELEQKYTIQVLGNATFDNLIVYQASLN 438 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGR 411 F EV + E+ PG ++ L+A D D + + Y G Sbjct: 439 VKLEDVNDNAPQFPQSVLEVSVEENNSPGAVILELSAFDRDSGSNGIIDYSF-GAELPME 497 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVF 469 F I + +G ++T + D +Q+ Y + V A+D G ++ + V I I D N+ P+F Sbjct: 498 FFIDASHG--ILTASVSFDREQKTSYTVIVLASDHGSPAQNGSCTVIITILDQNDNMPIF 555 Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 +T SV E+ TV +++ TD+D G+N +I+ S+ + +V D+ ++ Sbjct: 556 LTNEFTFSVPENLSRHGTVGIINVTDADSGLNGEISLSMLNTTMPFSV---DKNIIL--- 609 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF---KQQLY 586 LD E+ Y L + A D G P LS T V I V+D+NDN P+ Sbjct: 610 -----LEGYLDYESEYKYELWIEAHDKGNPPLSSTVKVNIMVLDMNDNAPLILLPDSNFS 664 Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKAL 645 + D L G+SV++V A D D G+NG I Y + G F ID +G I +++ Sbjct: 665 YVLVPPDTLKGSSVTKVHAVDYDAGMNGAIQYSGFGELGPLGDLFTIDNITGNITLKESI 724 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVI 672 + A D G P ST++ Sbjct: 725 IGHHCGLYQFMVKASDQGYPEALSTIV 751 Score = 138 bits (335), Expect = 2e-30 Identities = 110/367 (29%), Positives = 173/367 (47%), Gaps = 20/367 (5%) Query: 99 LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158 LLT LD E +YT+ V + + + A+++V + D NDN PQF + VS Sbjct: 403 LLTSGILDFELEQKYTIQVLGN---ATFDNLIVYQASLNVKLEDVNDNAPQFPQSVLEVS 459 Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYE 218 V+E+ S VI ++ A D D G+N I Y+ G M+F ID+ G ++ + D E Sbjct: 460 VEENNS--PGAVILELSAFDRDSGSNGIIDYSF-GAELPMEFFIDASHGILTASVSFDRE 516 Query: 219 QVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR 278 Q SY +++ A D GSP+++ + ++I I D NDN P F T+ F SV EN+ ++ Sbjct: 517 QKTSYTVIVLASDHGSPAQNGSCTVIITILDQNDNMPIFLTNEFTFSVPENLSRHGTVGI 576 Query: 279 VQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA 338 + DAD G+N E++ +M N +P ++D + G LD E++ KY+L + A Sbjct: 577 INVTDADSGLNGEISLSML------NTTMPFSVD--KNIILLEGYLDYESEYKYELWIEA 628 Query: 339 TDGGDPPRSATA-TXXXXXXXXXXXXXXFMPGQ--YEVELAEDEPPGTPVVTLTATDADE 395 D G+PP S+T +P V + D G+ V + A D D Sbjct: 629 HDKGNPPLSSTVKVNIMVLDMNDNAPLILLPDSNFSYVLVPPDTLKGSSVTKVHAVDYDA 688 Query: 396 DNRLHYEITGGNTRGRFS--ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG-GRSDT 452 + +G G T N G IT+ + + Y V A+D G + + Sbjct: 689 GMNGAIQYSGFGELGPLGDLFTIDNITGNITLKESIIGHHCGLYQFMVKASDQGYPEALS 748 Query: 453 AMVQINI 459 +V+INI Sbjct: 749 TIVRINI 755 >UniRef50_Q75QY0 Cluster: KIAA0811 protein; n=4; Eukaryota|Rep: KIAA0811 protein - Homo sapiens (Human) Length = 1123 Score = 219 bits (536), Expect = 7e-55 Identities = 143/445 (32%), Positives = 215/445 (48%), Gaps = 20/445 (4%) Query: 285 DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP 344 D+G NA++ Y++ D + + +ID +G + L QA +L V A+D G P Sbjct: 1 DQGANAQVVYSLPD-----SAEGHFSIDATTGVIRLEKPLQVRPQAPLELTVRASDLGTP 55 Query: 345 -PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEI 403 P S T F+ ++ V++ ED PPGT V+ L + Y + Sbjct: 56 IPLSTLGTVTVSVVGLEDYLPVFLNTEHSVQVPEDAPPGTEVLQLATLTRPGAEKTGYRV 115 Query: 404 TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV--SATDSGGRSDTAMVQINITD 461 GN +GRF + ++ G++ V LDF+ +Y L++ S S SD V +NITD Sbjct: 116 VSGNEQGRFRLDART--GILYVNASLDFETSPKYFLSIECSRKSSSSLSDVTTVMVNITD 173 Query: 462 ANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521 N + P F PY+ V E+A +G +L VSATD D +N+ ITYSL I + H Sbjct: 174 VNEHRPQFPQDPYSTRVLENALVGDVILTVSATDEDGPLNSDITYSL---IGGNQLGH-- 228 Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581 F I+P+ G + K LDRE S Y L + A D G P L + TD+ I V DVNDN P F Sbjct: 229 --FTIHPKKGELQVAKALDREQASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPPRF 286 Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641 Q Y+ + E++ +G+ V Q+ +D D NG + K +F + P G + T Sbjct: 287 FQLNYSTTVQENSPIGSKVLQLILSDPDSPENGPPYSFRITKGNNGSAFRVTP-DGWLVT 345 Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701 + L R + + L+ A D G PP SS VH+ + + + P + + E+ Sbjct: 346 AEGLSRRAQEWYQLQIQASDSGIPPLSSLTSVHVHVTEQSHYAPSALPLEIFITVGEDEF 405 Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSI 726 G +G+I A D D P + YS+ Sbjct: 406 QGGMVGKIHATDRD--PQDTLTYSL 428 Score = 187 bits (456), Expect = 3e-45 Identities = 127/374 (33%), Positives = 184/374 (49%), Gaps = 16/374 (4%) Query: 87 QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146 Q FR+D R+G L ASLD E +Y + ++ + ++S LS T+ VNI D N++ Sbjct: 121 QGRFRLDARTGILYVNASLDFETSPKYFLSIECSRKSS---SSLSDVTTVMVNITDVNEH 177 Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206 PQF + Y+ V E+ V D VI + ATD D NS I Y++IGGN F+I Sbjct: 178 RPQFPQDPYSTRVLENALVGD--VILTVSATDEDGPLNSDITYSLIGGNQLGHFTIHPKK 235 Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266 G++ + K LD EQ SY L +RA D G P T + I + DVNDN PRF+ + +V Sbjct: 236 GELQVAKALDREQASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPPRFFQLNYSTTV 295 Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326 EN PIG ++++ D D N Y+ + GN + P GW+ T+ L R Sbjct: 296 QENSPIGSKVLQLILSDPDSPENGP-PYSF--RITKGNNGSAFRVTP-DGWLVTAEGLSR 351 Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386 Q YQL + A+D G PP S+ + +P + + + EDE G V Sbjct: 352 RAQEWYQLQIQASDSGIPPLSSLTSVHVHVTEQSHYAPSALPLEIFITVGEDEFQGGMVG 411 Query: 387 TLTATDADEDNRLHYEITGGNTRGR-FSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445 + ATD D + L Y + T GR FS+ + +G+ I AQ L Y V+ +D Sbjct: 412 KIHATDRDPQDTLTYSLAEEETLGRHFSVGAPDGK--IIAAQGL---PRGHYSFNVTVSD 466 Query: 446 SGGRSDTAMVQINI 459 G + TA V + + Sbjct: 467 -GTFTTTAGVHVYV 479 Score = 166 bits (404), Expect = 7e-39 Identities = 134/472 (28%), Positives = 210/472 (44%), Gaps = 29/472 (6%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F ID +G + L A + V+A+D +P+ LS+ T+ V+++ D P Sbjct: 20 FSIDATTGVIRLEKPLQVRPQAPLELTVRASDLGTPIP--LSTLGTVTVSVVGLEDYLPV 77 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209 F ++V V ED + ++ AT GA Y ++ GN Q +F +D+ +G + Sbjct: 78 FLNTEHSVQVPED--APPGTEVLQL-ATLTRPGAEKT-GYRVVSGNEQGRFRLDARTGIL 133 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269 + +LD+E Y L I S S S+ T +++NI DVN++ P+F + V EN Sbjct: 134 YVNASLDFETSPKYFLSIECSRKSSSSLSDVTTVMVNITDVNEHRPQFPQDPYSTRVLEN 193 Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329 +G I+ V A D D +N+++TY++ + G+ TI P+ G + + LDRE Sbjct: 194 ALVGDVILTVSATDEDGPLNSDITYSLIGGNQLGH----FTIHPKKGELQVAKALDREQA 249 Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389 + Y L + ATD G PP F Y + E+ P G+ V+ L Sbjct: 250 SSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPPRFFQLNYSTTVQENSPIGSKVLQLI 309 Query: 390 ATDADEDNR---LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446 +D D + IT GN F +T G + A+ L + + Y L + A+DS Sbjct: 310 LSDPDSPENGPPYSFRITKGNNGSAFRVTPD---GWLVTAEGLSRRAQEWYQLQIQASDS 366 Query: 447 G--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504 G S V +++T+ ++YAP +V ED G V + ATD D + Sbjct: 367 GIPPLSSLTSVHVHVTEQSHYAPSALPLEIFITVGEDEFQGGMVGKIHATDRDP--QDTL 424 Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556 TYSL+ E E + H F + G I + L R Y VT DG Sbjct: 425 TYSLAEE---ETLGRH---FSVGAPDGKIIAAQGLPR---GHYSFNVTVSDG 467 Score = 124 bits (300), Expect = 3e-26 Identities = 132/486 (27%), Positives = 212/486 (43%), Gaps = 38/486 (7%) Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556 D G NAQ+ YSL + A H F I+ TG I K L + LTV A D Sbjct: 1 DQGANAQVVYSLP----DSAEGH----FSIDATTGVIRLEKPLQVRPQAPLELTVRASDL 52 Query: 557 GVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615 G P LS V +SVV + D PVF ++ + EDA GT V Q+ AT G + Sbjct: 53 GTPIPLSTLGTVTVSVVGLEDYLPVFLNTEHSVQVPEDAPPGTEVLQL-ATLTRPGAE-K 110 Query: 616 IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675 Y + E+G F +D +G++ N +LD E+ + L + S V + Sbjct: 111 TGYRV-VSGNEQGRFRLDARTGILYVNASLDFETSPKYFLSIECSRKSSSSLSDVTTVMV 169 Query: 676 KIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735 I D+N+ P F D + + EN+ +G I + A D D N+ + YS+ GG+ F Sbjct: 170 NITDVNEHRPQFPQDPYSTRVLENALVGDVILTVSATDEDGPLNSDITYSLIGGNQLGHF 229 Query: 736 SLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792 ++ ++G EL LD E Y L +RA PPL D + I V DVNDN P Sbjct: 230 TIHPKKG----ELQVAKALDREQ-ASSYSLKLRATDSGQPPLHEDTDIAIQVADVNDNPP 284 Query: 793 VMKDFQIIFN-NYKDCFPVG-PFGRVPAYDADVTDK---LQYRILSGNNANLILLNETTG 847 + FQ+ ++ ++ P+G ++ D D + +RI GNN + + G Sbjct: 285 --RFFQLNYSTTVQENSPIGSKVLQLILSDPDSPENGPPYSFRITKGNNGSAFRVT-PDG 341 Query: 848 SMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAE 906 + + L+ + +++ +D G+ + ++ + V +TE+ + L ++ Sbjct: 342 WLVTAEGLSRRAQEWYQLQIQASDSGIPPLSSLTSVHVH-VTEQSHYAPSALPL-EIFIT 399 Query: 907 QFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVA-GD 965 G + + A P++ + +++T L FS PD ++ A G Sbjct: 400 VGEDEFQGGMVGKIHATDRDPQDTLTYSLAEEET------LGRHFSVGAPDGKIIAAQGL 453 Query: 966 PSPHYS 971 P HYS Sbjct: 454 PRGHYS 459 Score = 93.9 bits (223), Expect = 6e-17 Identities = 83/332 (25%), Positives = 144/332 (43%), Gaps = 34/332 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +N+ D N+H P F Y V E A G +LT+ ATD+D N+++ Y+ L+ + L Sbjct: 169 VNITDVNEHRPQFPQDPYSTRVLENALVGDVILTVSATDEDGPLNSDITYS--LIGGNQL 226 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F I + G L +LDRE+ + Y++ ++ATD P L Sbjct: 227 GH-----------------FTIHPKKGELQVAKALDREQASSYSLKLRATDSGQP---PL 266 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS-AIRY 189 I + + D NDN P+F + Y+ +V E+ + + ++ +D D N + Sbjct: 267 HEDTDIAIQVADVNDNPPRFFQLNYSTTVQENSPIGSK--VLQLILSDPDSPENGPPYSF 324 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I GN F + + G + + L Y+L I+A D G P S+ T + +++ + Sbjct: 325 RITKGNNGSAFRV-TPDGWLVTAEGLSRRAQEWYQLQIQASDSGIPPLSSLTSVHVHVTE 383 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 + AP +V E+ G + ++ A D D LTY++ +++ G Sbjct: 384 QSHYAPSALPLEIFITVGEDEFQGGMVGKIHATDRDP--QDTLTYSLAEEETLGR---HF 438 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341 ++ G + + L R Y VT +DG Sbjct: 439 SVGAPDGKIIAAQGLPR---GHYSFNVTVSDG 467 Score = 36.7 bits (81), Expect = 9.2 Identities = 24/80 (30%), Positives = 33/80 (41%), Gaps = 7/80 (8%) Query: 1276 VKNKDFVGCISDFYIDHKFIDL---NSYVA---DNGTLAGCPEKRSRCSSAPCYNGAECS 1329 V K F GC+ ++ + +DL VA + L C CS C NG +CS Sbjct: 678 VSLKGFEGCLDAVVVNEEALDLLAPGKTVAGLLETQALTQCCLHSDYCSQNTCLNGGKCS 737 Query: 1330 DLWDT-YICDCKEGHTGKDC 1348 Y+C C +GK C Sbjct: 738 WTHGAGYVCKCPPQFSGKHC 757 >UniRef50_Q86N71 Cluster: Cadherin-related protein; n=1; Aplysia californica|Rep: Cadherin-related protein - Aplysia californica (California sea hare) Length = 1172 Score = 219 bits (535), Expect = 9e-55 Identities = 190/691 (27%), Positives = 317/691 (45%), Gaps = 59/691 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 IN+ D ND+ P F+ + + E + G T A D+D G+N+ YT+ L Sbjct: 154 INITDINDNMPTFKPSEITLDIPENNAVGLTKPLPTAMDRDTGQNSVQHYTL-------L 206 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P + + + FR+ +L+ ASLDRE YT+LV A D +P L Sbjct: 207 EP--SGPFSLDVERRLNNRFRL-----SLVADASLDRELQGHYTLLVVAEDGGAP---SL 256 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + T T+HVN+ D+NDN P F+++ Y+ SV E V + V+ K+ ATD D+G N+ +RY+ Sbjct: 257 TGTMTVHVNVTDENDNSPVFTQEEYSYSVGETERVGE--VVGKLTATDVDLGKNADVRYS 314 Query: 191 IIGGNTQMQ----FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 +I + F+++ L+G++++ L+Y+ ++ V+ A+D G +R +L ++ Sbjct: 315 LIFSTKDQRGGELFAVEQLTGEITIKAPLEYDAGSTFSAVVEARDRGDIARLTEARLSLS 374 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 I +V +NAPR +L Q++V N VR+ ++ +LT T D +G V Sbjct: 375 IVNVGNNAPRLSITL-QKTVRANT------VRISEGARNKTFVGKLTATDNDPGDSGKVQ 427 Query: 307 LPIT--------IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358 I P + +G LDRE Q + + +D G P ++++++ Sbjct: 428 CHSAHPNFQTNRIGPHEFTIIMNGTLDRERQDTIDVTLVCSDAGAPRKTSSSSFRVVVTD 487 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEIT-GGNTRGRFSITSQ 417 F Y V + E+ G ++ L A D D + + F I S+ Sbjct: 488 VNDNPPRFSQETYVVNVTEENIVGKHILKLRAEDPDYGVNKEFSYSLFPKENDVFGIDSK 547 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYT 475 + G++T D + ER+ + V+ATD G S TA V +NI D N+ P E Sbjct: 548 D--GILTARTTFDHELERKVNVIVTATDRGTPSLVSTATVVVNILDINDNYP--ELTTTE 603 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSL--SSEISNEAVAHHDQQFVINPQTGAI 533 V E+ V + TD D G NA++ +S+ +S+I+ Q F ++P G + Sbjct: 604 LRVPEEGGKMMLVGTLEGTDKDSGRNARLIFSMPPTSDITG-------QMFKVDPD-GRV 655 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF---KQQLYTANI 590 + LDRE+ S Y L++ RD GV V + V DVND+ P F + T + Sbjct: 656 FAIQNLDRESRSFYSLSIELRDDGVEPKVVYGTVNVIVEDVNDHAPSFHFPTPKNKTVSF 715 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650 + ++++ ATD D G N I Y + D+ + F ++ +G + + + Sbjct: 716 VWSLPTYVPITRLNATDGDAGENQTISYYIFSGDKTD-LFRLEKDTGNLFLRRKVKATDD 774 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681 L A D G Q S + + I+ N Sbjct: 775 QLQTLMVAAHDWGVDQQESQTFIDLVIDITN 805 Score = 209 bits (511), Expect = 7e-52 Identities = 181/679 (26%), Positives = 300/679 (44%), Gaps = 43/679 (6%) Query: 89 VFRIDGRSGALLTRASLDREKVAR---YTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145 +F I+ RSGAL + +DRE V ++ S V+D +++NI D ND Sbjct: 103 LFSINRRSGALSSHTMIDRETVCEGMDECIISFDVTVTSDVTD-FFRLVVVNINITDIND 161 Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205 N P F T+ + E+ +V + A D D G NS Y ++ + ++ Sbjct: 162 NMPTFKPSEITLDIPENNAVGLTKPLPT--AMDRDTGQNSVQHYTLLEPSGPFSLDVERR 219 Query: 206 SGD---VSLVK--TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260 + +SLV +LD E Y L++ A+DGG+PS + T + +N+ D NDN+P F Sbjct: 220 LNNRFRLSLVADASLDRELQGHYTLLVVAEDGGAPSLTGTMTVHVNVTDENDNSPVFTQE 279 Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM--TDKDYTGNVDLPITIDPRSGWV 318 + SV E +G + ++ A D D G NA++ Y++ + KD G +L ++ +G + Sbjct: 280 EYSYSVGETERVGEVVGKLTATDVDLGKNADVRYSLIFSTKDQRGG-EL-FAVEQLTGEI 337 Query: 319 YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE------ 372 L+ + + + +V A D GD R A + Sbjct: 338 TIKAPLEYDAGSTFSAVVEARDRGDIARLTEARLSLSIVNVGNNAPRLSITLQKTVRANT 397 Query: 373 VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ--PLD 430 V ++E T V LTATD D + + + + T++ G T+ LD Sbjct: 398 VRISEGARNKTFVGKLTATDNDPGDSGKVQCHSAHPNFQ---TNRIGPHEFTIIMNGTLD 454 Query: 431 FKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 +++ +T+ +D+G ++ ++ ++ +TD N+ P F Y +V E+ +G + Sbjct: 455 RERQDTIDVTLVCSDAGAPRKTSSSSFRVVVTDVNDNPPRFSQETYVVNVTEENIVGKHI 514 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 L + A D D G+N + +YSL + + F I+ + G +T D E Sbjct: 515 LKLRAEDPDYGVNKEFSYSLFPK--------ENDVFGIDSKDGILTARTTFDHELERKVN 566 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 + VTA D G PSL T V ++++D+NDN P + + E+ V + TD Sbjct: 567 VIVTATDRGTPSLVSTATVVVNILDINDNYP--ELTTTELRVPEEGGKMMLVGTLEGTDK 624 Query: 609 DVGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 D G N R+ + + P G F +DP G + + LDRES + + L D G P+ Sbjct: 625 DSGRNARLIFSMPPTSDITGQMFKVDP-DGRVFAIQNLDRESRSFYSLSIELRDDGVEPK 683 Query: 668 SSTVIVHIKIEDINDSPPVFESDC---LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 V++ +ED+ND P F T + P I + A D D G N + Y Sbjct: 684 VVYGTVNVIVEDVNDHAPSFHFPTPKNKTVSFVWSLPTYVPITRLNATDGDAGENQTISY 743 Query: 725 SIKGGDDSNSFSLETRQGS 743 I GD ++ F LE G+ Sbjct: 744 YIFSGDKTDLFRLEKDTGN 762 Score = 208 bits (508), Expect = 2e-51 Identities = 187/654 (28%), Positives = 273/654 (41%), Gaps = 40/654 (6%) Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 INI D+NDN P F S + EN +G + A D D G N+ YT+ + + Sbjct: 154 INITDINDNMPTFKPSEITLDIPENNAVGLTKPLPTAMDRDTGQNSVQHYTLLEPSGPFS 213 Query: 305 VDLPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 +D+ ++ R + LDRE Q Y LLV A DGG P + T T Sbjct: 214 LDVERRLNNRFRLSLVADASLDRELQGHYTLLVVAEDGGAPSLTGTMTVHVNVTDENDNS 273 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDAD----EDNRLHYEITGGNTRGRFSITSQNG 419 F +Y + E E G V LTATD D D R + + RG + Sbjct: 274 PVFTQEEYSYSVGETERVGEVVGKLTATDVDLGKNADVRYSLIFSTKDQRGGELFAVEQL 333 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENA----- 472 G IT+ PL++ + V A D G R A + ++I + N AP Sbjct: 334 TGEITIKAPLEYDAGSTFSAVVEARDRGDIARLTEARLSLSIVNVGNNAPRLSITLQKTV 393 Query: 473 -PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 T + E A T V ++ATD+D G S ++ + + Q I P Sbjct: 394 RANTVRISEGARNKTFVGKLTATDNDPGD--------SGKVQCHSAHPNFQTNRIGPHEF 445 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 I N LDRE +T+ D G P + ++ + V DVNDN P F Q+ Y N+ Sbjct: 446 TIIMNGTLDRERQDTIDVTLVCSDAGAPRKTSSSSFRVVVTDVNDNPPRFSQETYVVNVT 505 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA 651 E+ +VG + ++ A D D G+N Y L PK E F ID G++ D E Sbjct: 506 EENIVGKHILKLRAEDPDYGVNKEFSYSLFPK--ENDVFGIDSKDGILTARTTFDHELER 563 Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711 ++ A D GTP ST V + I DIND+ P E + E +G + Sbjct: 564 KVNVIVTATDRGTPSLVSTATVVVNILDINDNYP--ELTTTELRVPEEGGKMMLVGTLEG 621 Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771 D D G NA + +S+ D + + + +LD ES R Y L I Sbjct: 622 TDKDSGRNARLIFSMPPTSDITGQMFKV---DPDGRVFAIQNLDRES-RSFYSLSIELRD 677 Query: 772 PPLWNDV---RVEILVTDVNDNAPVMKDFQIIFN---NYKDCFPV-GPFGRVPAYDADVT 824 + V V ++V DVND+AP F N ++ P P R+ A D D Sbjct: 678 DGVEPKVVYGTVNVIVEDVNDHAPSF-HFPTPKNKTVSFVWSLPTYVPITRLNATDGDAG 736 Query: 825 DK--LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNE 875 + + Y I SG+ +L L + TG++ L ++ +L T+ V+ D GV++ Sbjct: 737 ENQTISYYIFSGDKTDLFRLEKDTGNLFLRRKVKATDDQLQTLMVAAHDWGVDQ 790 Score = 128 bits (308), Expect = 3e-27 Identities = 116/435 (26%), Positives = 192/435 (44%), Gaps = 29/435 (6%) Query: 454 MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL---SS 510 +V INITD N+ P F+ + T + E+ +G T + +A D D G N+ Y+L S Sbjct: 151 VVNINITDINDNMPTFKPSEITLDIPENNAVGLTKPLPTAMDRDTGQNSVQHYTLLEPSG 210 Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570 S + + +F ++ + + LDRE Y L V A DGG PSL+ T V ++ Sbjct: 211 PFSLDVERRLNNRFRLS-----LVADASLDRELQGHYTLLVVAEDGGAPSLTGTMTVHVN 265 Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDREEG 628 V D NDN PVF Q+ Y+ ++ E VG V ++ ATD D+G N + Y L KD+ G Sbjct: 266 VTDENDNSPVFTQEEYSYSVGETERVGEVVGKLTATDVDLGKNADVRYSLIFSTKDQRGG 325 Query: 629 S-FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687 F ++ +G I L+ ++ +T A D G + + + + I ++ ++ P Sbjct: 326 ELFAVEQLTGEITIKAPLEYDAGSTFSAVVEARDRGDIARLTEARLSLSIVNVGNNAPRL 385 Query: 688 ESD------CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH-YSIKGGDDSNSFSLETR 740 T ISE + T +G++ A D D G + V +S +N R Sbjct: 386 SITLQKTVRANTVRISEGARNKTFVGKLTATDNDPGDSGKVQCHSAHPNFQTN------R 439 Query: 741 QGSDKAELVTMVDLDYE-SPRKKYELVIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQ 798 G + ++ LD E LV A +P + ++VTDVNDN P Sbjct: 440 IGPHEFTIIMNGTLDRERQDTIDVTLVCSDAGAPRKTSSSSFRVVVTDVNDNPPRFSQET 499 Query: 799 IIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 + N ++ ++ A D D V + Y + N ++ ++ G +T + Sbjct: 500 YVVNVTEENIVGKHILKLRAEDPDYGVNKEFSYSLFPKEN-DVFGIDSKDGILTARTTFD 558 Query: 857 TNVPKLATMEVSVTD 871 + + + V+ TD Sbjct: 559 HELERKVNVIVTATD 573 Score = 115 bits (276), Expect = 2e-23 Identities = 103/346 (29%), Positives = 161/346 (46%), Gaps = 38/346 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ V D ND+ P F + Y +V E G +L L+A D D G N E Y + Sbjct: 482 RVVVTDVNDNPPRFSQETYVVNVTEENIVGKHILKLRAEDPDYGVNKEFSY--------S 533 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L P++ DVF ID + G L R + D E + V+V ATD+ +P Sbjct: 534 LFPKE------------NDVFGIDSKDGILTARTTFDHELERKVNVIVTATDRGTP---S 578 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L STAT+ VNI+D NDNYP+ + T + V E+ ++ ++ TD D G N+ + + Sbjct: 579 LVSTATVVVNILDINDNYPELT--TTELRVPEEGG--KMMLVGTLEGTDKDSGRNARLIF 634 Query: 190 AI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 ++ T F +D G V ++ LD E Y L I +D G + + + + Sbjct: 635 SMPPTSDITGQMFKVDP-DGRVFAIQNLDRESRSFYSLSIELRDDGVEPKVVYGTVNVIV 693 Query: 248 RDVNDNAPRF-YTSLFQESVS--ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 DVND+AP F + + ++VS ++P I R+ A D D G N ++Y + D T Sbjct: 694 EDVNDHAPSFHFPTPKNKTVSFVWSLPTYVPITRLNATDGDAGENQTISYYIFSGDKT-- 751 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPPRSAT 349 DL ++ +G ++ ++ L+V A D G D S T Sbjct: 752 -DL-FRLEKDTGNLFLRRKVKATDDQLQTLMVAAHDWGVDQQESQT 795 Score = 111 bits (268), Expect = 2e-22 Identities = 88/291 (30%), Positives = 140/291 (48%), Gaps = 33/291 (11%) Query: 524 FVINPQTGAITTNKLLDRETM-SGYLLTVTARDGGVPSLSDTTD------VEISVVDVND 576 F IN ++GA++++ ++DRET+ G + + D V SD TD V I++ D+ND Sbjct: 104 FSINRRSGALSSHTMIDRETVCEGMDECIISFD--VTVTSDVTDFFRLVVVNINITDIND 161 Query: 577 NEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPA 635 N P FK T +I E+ VG + A D D G N HY L+P G F +D Sbjct: 162 NMPTFKPSEITLDIPENNAVGLTKPLPTAMDRDTGQNSVQHYTLLEP----SGPFSLDVE 217 Query: 636 SGV-------IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688 + + + +LDRE + L VA DGG P + T+ VH+ + D ND+ PVF Sbjct: 218 RRLNNRFRLSLVADASLDRELQGHYTLLVVAEDGGAPSLTGTMTVHVNVTDENDNSPVFT 277 Query: 689 SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI----KGGDDSNSFSLETRQGSD 744 + ++ + E +G +G++ A D D G NA V YS+ K F++E G Sbjct: 278 QEEYSYSVGETERVGEVVGKLTATDVDLGKNADVRYSLIFSTKDQRGGELFAVEQLTG-- 335 Query: 745 KAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792 E+ L+Y++ + V+ A + R+ + + +V +NAP Sbjct: 336 --EITIKAPLEYDA-GSTFSAVVEARDRGDIARLTEARLSLSIVNVGNNAP 383 Score = 82.2 bits (194), Expect = 2e-13 Identities = 76/268 (28%), Positives = 118/268 (44%), Gaps = 18/268 (6%) Query: 620 LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST-----VIVH 674 LDP + E F I+ SG + ++ +DRE+V + + T T V+V+ Sbjct: 94 LDPNNAETHLFSINRRSGALSSHTMIDRETVCEGMDECIISFDVTVTSDVTDFFRLVVVN 153 Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS 734 I I DIND+ P F+ +T I EN+ +G T A D D G N+V HY++ S Sbjct: 154 INITDINDNMPTFKPSEITLDIPENNAVGLTKPLPTAMDRDTGQNSVQHYTLLEPSGPFS 213 Query: 735 FSLETRQGSD-KAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDN 790 +E R + + LV LD E + Y L++ A +P L + V + VTD NDN Sbjct: 214 LDVERRLNNRFRLSLVADASLDREL-QGHYTLLVVAEDGGAPSLTGTMTVHVNVTDENDN 272 Query: 791 APVMKDFQIIFNNYKDCFPVGP-FGRVPAYD------ADVTDKLQYRILSGNNANLILLN 843 +PV + + + + VG G++ A D ADV L + L + Sbjct: 273 SPVFTQEEYSY-SVGETERVGEVVGKLTATDVDLGKNADVRYSLIFSTKDQRGGELFAVE 331 Query: 844 ETTGSMTLSPQLNTNVPKLATMEVSVTD 871 + TG +T+ L + + V D Sbjct: 332 QLTGEITIKAPLEYDAGSTFSAVVEARD 359 >UniRef50_O14917 Cluster: Protocadherin-17 precursor; n=23; Euteleostomi|Rep: Protocadherin-17 precursor - Homo sapiens (Human) Length = 1159 Score = 219 bits (535), Expect = 9e-55 Identities = 167/591 (28%), Positives = 263/591 (44%), Gaps = 34/591 (5%) Query: 182 GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 G + + Y ++ + +D+ SG + + +D E + + + + Sbjct: 57 GRSKSGSYRVLENSAPHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDKEIC 116 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 + + I+D+NDNAP F + + +SEN G A+D D G N TY +T D+ Sbjct: 117 MIKVEIQDINDNAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDH 176 Query: 302 -TGNVDLPITID-PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 +D+ D + + LDRE Q + L++TA DGG+PPRSAT Sbjct: 177 GLFGLDVKSRGDGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDS 236 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITG---GNTRGRFSI 414 F Y VEL E+ P GT V+ L ATDADE + + Y + R FSI Sbjct: 237 NDNSPVFEAPSYLVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSI 296 Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENA 472 + G LI V LD+++ + V A D G A V + + D N+ AP Sbjct: 297 DPKTG--LIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFV 354 Query: 473 PYT-ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE----------AVAHHD 521 ++ E AP GT + +V TD D G N Q+ + +V Sbjct: 355 SVRQGALSEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKL 414 Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581 ++ N T + T++ LDRET Y +T+ ARDGG P L+ T I ++D NDN P F Sbjct: 415 EENYDNFYT--VVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRF 472 Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV----IDPASG 637 + LY + E+ + G + V A D D+G NG + Y + P + S ++P +G Sbjct: 473 TKGLYVLQVHENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNG 532 Query: 638 VIRTNKALDRESVATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPV-----FESDC 691 I ++ + E + K +A D G P S V + + D+ND+ PV ++D Sbjct: 533 AIYALRSFNFEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDT 592 Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 + N+ +G + +RA D D G + + Y I G+D + F ++ G Sbjct: 593 AELQVPRNAGLGYLVSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSG 643 Score = 210 bits (513), Expect = 4e-52 Identities = 187/629 (29%), Positives = 285/629 (45%), Gaps = 51/629 (8%) Query: 92 IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151 +D SG L T+ +DRE + R+ + + + +D+ I V I D NDN P FS Sbjct: 77 VDADSGLLYTKQRIDRESLCRHNAKCQLSLEVF-ANDK--EICMIKVEIQDINDNAPSFS 133 Query: 152 EKTYTVSVDEDISV-TDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS-GD- 208 + + E+ + T P+ + A D D G N Y + + + F +D S GD Sbjct: 134 SDQIEMDISENAAPGTRFPLTS---AHDPDAGENGLRTYLLTRDDHGL-FGLDVKSRGDG 189 Query: 209 -----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263 + + K LD EQ + LV+ A DGG P RS T Q+ + + D NDN+P F + Sbjct: 190 TKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYL 249 Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323 + EN P+G ++ + A DADEG N E+ Y+ + V +IDP++G + G Sbjct: 250 VELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSY-VPDRVRELFSIDPKTGLIRVKGN 308 Query: 324 LDRETQAKYQLLVTATD-GGDP-PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381 LD E ++ V A D G +P P T F+ + + L+E PP Sbjct: 309 LDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVR-QGALSEAAPP 367 Query: 382 GTPVVTLTATDAD--EDNRLHYEITGGNTRGR------------FSITSQNGRGLITVA- 426 GT + + TD D ++ +L + GG G F + +N TV Sbjct: 368 GTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKL-EENYDNFYTVVT 426 Query: 427 -QPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 +PLD + + Y +T+ A D G + T I I D N+ P F Y V E+ Sbjct: 427 DRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNI 486 Query: 484 IGTTVLVVSATDSDVGINAQITYS-LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 G + V A D D+G N ++YS L S I + ++ + +NP GAI + + E Sbjct: 487 PGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVS---VNPTNGAIYALRSFNFE 543 Query: 543 TMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVF---KQQLYTANIM--EDALV 596 + V A+D G P+ L V ++V+DVNDN PV Q TA + +A + Sbjct: 544 QTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAELQVPRNAGL 603 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 G VS V A D+D G +GR+ YE+ ++ F IDP+SG IRT + +L Sbjct: 604 GYLVSTVRALDSDFGESGRLTYEI-VDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELV 662 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPP 685 D G P S+ + + I ++ S P Sbjct: 663 VKVTDHGKPTLSA--VAKLIIRSVSGSLP 689 Score = 194 bits (474), Expect = 2e-47 Identities = 167/616 (27%), Positives = 280/616 (45%), Gaps = 41/616 (6%) Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 + +D SG +YT ++DRE+ ++ + F Sbjct: 75 LDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDKEICMIKVEIQDINDNAPSFSS 134 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSI-TSQNGRGL---- 422 Q E++++E+ PGT +A D D +N L + + G F + G G Sbjct: 135 DQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRGDGTKFPE 194 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFE 480 + + + LD +Q+ + L ++A D G +A VQIN+ D+N+ +PVFE Y + E Sbjct: 195 LVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSYLVELPE 254 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 +AP+GT V+ ++ATD+D G N ++ YS SS + + + F I+P+TG I LD Sbjct: 255 NAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRV----RELFSIDPKTGLIRVKGNLD 310 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP-VFKQQLYTANIMEDALVGTS 599 E + V ARD G + V + ++D NDN P + + + E A GT Sbjct: 311 YEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQGALSEAAPPGTV 370 Query: 600 VSQVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGV-------------IRTNKAL 645 ++ V TD D G NG++ L G + P V + T++ L Sbjct: 371 IALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDRPL 430 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 DRE+ +++ VA DGG+PP +ST IKI D ND+PP F + EN+ G Sbjct: 431 DRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIPGEY 490 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRK-KY 763 +G + A DPD G N V YSI + S + + ++E + ++ Sbjct: 491 LGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAFEF 550 Query: 764 ELVIRAASPP--LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG------R 815 +++ + + P L ++ V + V DVNDNAPV+ + N+ + G Sbjct: 551 KVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIV-LPTLQNDTAELQVPRNAGLGYLVST 609 Query: 816 VPAYDADVTD--KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-G 872 V A D+D + +L Y I+ GN+ +L ++ ++G + +V + + V VTD G Sbjct: 610 VRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVTDHG 669 Query: 873 VNEIKAMMQLSVRLIT 888 + A+ +L +R ++ Sbjct: 670 KPTLSAVAKLIIRSVS 685 Score = 180 bits (438), Expect = 5e-43 Identities = 161/582 (27%), Positives = 256/582 (43%), Gaps = 55/582 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ + D ND++P F Q E + E A+ GT A D D G+N Y L+T D Sbjct: 119 KVEIQDINDNAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTY---LLTRD- 174 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 + R DG + L+ + +LDRE+ +T+++ A D P Sbjct: 175 ----------DHGLFGLDVKSRGDGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPR- 223 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 S+T I+V +ID NDN P F +Y V + E+ + V+ + ATDAD G N + Sbjct: 224 --SATVQINVKVIDSNDNSPVFEAPSYLVELPENAPL--GTVVIDLNATDADEGPNGEVL 279 Query: 189 YAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 Y+ + + FSID +G + + LDYE+ + ++A+D G ++ + Sbjct: 280 YSFSSYVPDRVRELFSIDPKTGLIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTV 339 Query: 246 NIRDVNDNAPRF-YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG- 303 + D NDNAP + S+ Q ++SE P G I V+ D D G N +L + TG Sbjct: 340 KLIDRNDNAPSIGFVSVRQGALSEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGG 399 Query: 304 -------NVDLPITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353 +P ++ Y T LDRETQ +Y + + A DGG PP ++T + Sbjct: 400 GGGLGGPGGSVPFKLEENYDNFYTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFA 459 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTR-- 409 F G Y +++ E+ PG + ++ A D D ++ + Y I + Sbjct: 460 IKILDENDNPPRFTKGLYVLQVHENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDV 519 Query: 410 GRFSITSQN-GRGLITVAQPLDFKQERRYVLTVSATDSGGRS---DTAMVQINITDANNY 465 ++ S N G I + +F+Q + + V A DSG + A V++ + D N+ Sbjct: 520 SIYTYVSVNPTNGAIYALRSFNFEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDN 579 Query: 466 APV-----FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520 APV +N V +A +G V V A DSD G + ++TY + + Sbjct: 580 APVIVLPTLQNDTAELQVPRNAGLGYLVSTVRALDSDFGESGRLTYEIVD-------GND 632 Query: 521 DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 D F I+P +G I T + L V D G P+LS Sbjct: 633 DHLFEIDPSSGEIRTLHPFWEDVTPVVELVVKVTDHGKPTLS 674 Score = 150 bits (364), Expect = 5e-34 Identities = 145/548 (26%), Positives = 231/548 (42%), Gaps = 52/548 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V+D ND+SPVFE Y + E A GT V+ L ATD D G N EV Y+ D Sbjct: 231 VKVIDSNDNSPVFEAPSYLVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDR- 289 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 V+++F ID ++G + + +LD E+ + V+A D + + Sbjct: 290 ---------------VRELFSIDPKTGLIRVKGNLDYEENGMLEIDVQARDLGP---NPI 331 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + + V +ID NDN P + + + VIA ++ TD D G N ++ Sbjct: 332 PAHCKVTVKLIDRNDNAPSIGFVSVRQGALSE-AAPPGTVIALVRVTDRDSGKNGQLQCR 390 Query: 191 IIGGNT------------QMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSP 235 ++GG + F ++ + V T LD E Y + I A+DGGSP Sbjct: 391 VLGGGGTGGGGGLGGPGGSVPFKLEENYDNFYTVVTDRPLDRETQDEYNVTIVARDGGSP 450 Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295 ++T I I D NDN PRF L+ V EN G + V A D D G N ++Y+ Sbjct: 451 PLNSTKSFAIKILDENDNPPRFTKGLYVLQVHENNIPGEYLGSVLAQDPDLGQNGTVSYS 510 Query: 296 MTDKDYTGNVDL--PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR-SATATX 352 + + G+V + ++++P +G +Y + E ++ V A D G P + AT Sbjct: 511 IL-PSHIGDVSIYTYVSVNPTNGAIYALRSFNFEQTKAFEFKVLAKDSGAPAHLESNATV 569 Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPP-----GTPVVTLTATDAD--EDNRLHYEITG 405 + + + AE + P G V T+ A D+D E RL YEI Sbjct: 570 RVTVLDVNDNAPVIVLPTLQNDTAELQVPRNAGLGYLVSTVRALDSDFGESGRLTYEIVD 629 Query: 406 GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNY 465 GN F I +G I P L V TD G + +A+ ++ I + Sbjct: 630 GNDDHLFEIDPSSGE--IRTLHPFWEDVTPVVELVVKVTDHGKPTLSAVAKLIIRSVSGS 687 Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525 P E P + ++V +T S + + A IT ++ + N+ + ++ + Sbjct: 688 LP--EGVPRVNGEQHHWDMSLPLIVTLSTISIILLAAMITIAVKCKRENKEIRTYNCRIA 745 Query: 526 --INPQTG 531 +PQ G Sbjct: 746 EYSHPQLG 753 >UniRef50_Q9HCL0 Cluster: Protocadherin-18 precursor; n=33; Euteleostomi|Rep: Protocadherin-18 precursor - Homo sapiens (Human) Length = 1128 Score = 219 bits (534), Expect = 1e-54 Identities = 183/631 (29%), Positives = 297/631 (47%), Gaps = 50/631 (7%) Query: 170 VIAKIKATDADVGAN----SAIRY-AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR 224 VIA++ ADV S +R+ A+ GN+ + ++ +G++S+ T+D EQ+ Sbjct: 36 VIARLSEDVADVLLKLPNPSTVRFRAMQRGNSPL-LVVNEDNGEISIGATIDREQLCQKN 94 Query: 225 LVIRAQDGGSPSRSNTTQLL---INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA 281 L + + QL + + D+NDN+P+F SL +SE+ +G I A Sbjct: 95 LNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQFSRSLIPIEISESAAVGTRIPLDSA 154 Query: 282 YDADEGVNAELTYTMTDKDYTGNVDLPITID-PRSGWVYTSGQLDRETQAKYQLLVTATD 340 +D D G N+ TY+++ D+ N+++ D + + +LDRE ++ Y+L +TA+D Sbjct: 155 FDPDVGENSLHTYSLSANDFF-NIEVRTRTDGAKYAELIVVRELDRELKSSYELQLTASD 213 Query: 341 GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNR 398 G P RS ++ F Y ++L E+ P GT ++ L ATD DE + + Sbjct: 214 MGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSPVGTLLLDLNATDPDEGANGK 273 Query: 399 LHYEIT---GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA-- 453 + Y + F I S+ RG +T+ + +D++ + Y + V A D G S A Sbjct: 274 IVYSFSSHVSPKIMETFKIDSE--RGHLTLFKQVDYEITKSYEIDVQAQDLGPNSIPAHC 331 Query: 454 MVQINITDANNYAP------VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507 + I + D N+ P + + +FE PI T V +V D D G+N +I Sbjct: 332 KIIIKVVDVNDNKPEININLMSPGKEEISYIFEGDPIDTFVALVRVQDKDSGLNGEIVCK 391 Query: 508 LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567 L + ++ ++ I TN LDRE S Y LTV A D G PSLS Sbjct: 392 LHGHGHFKLQKTYENNYL-------ILTNATLDREKRSEYSLTVIAEDRGTPSLSTVKHF 444 Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627 + + D+NDN P F++ Y I E+ G ++ V ATD D+G NG++ Y + Sbjct: 445 TVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLGENGQVTYTILESFILG 504 Query: 628 GSF----VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ--SSTVIVHIKIEDIN 681 S IDP++G I + D E V+ A DGG+P Q S+T +V + I D N Sbjct: 505 SSITTYVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGSPKQLVSNTTVV-LTIIDEN 563 Query: 682 DSPPV-----FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736 D+ PV ++ I + + G + IRA D D G NA + +I G++ N F Sbjct: 564 DNVPVVIGPALRNNTAEITIPKGAESGFHVTRIRAIDRDSGVNAELSCAIVAGNEENIFI 623 Query: 737 LETRQGSDKAELVTMVDLDYESPRKKYELVI 767 ++ R ++ T V +D P ++EL + Sbjct: 624 IDPR----SCDIHTNVSMD-SVPYTEWELSV 649 Score = 207 bits (506), Expect = 3e-51 Identities = 174/611 (28%), Positives = 273/611 (44%), Gaps = 34/611 (5%) Query: 96 SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155 +G + A++DRE++ + + + I V ++D NDN PQFS Sbjct: 76 NGEISIGATIDREQLCQKNLNCSIEFDVITLPTEHLQLFHIEVEVLDINDNSPQFSRSLI 135 Query: 156 TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG---NTQMQFSIDSLS-GDVSL 211 + + E +V I A D DVG NS Y++ N +++ D ++ + Sbjct: 136 PIEISESAAVGTR--IPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKYAELIV 193 Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271 V+ LD E SY L + A D G P RS ++ L I+I D NDN+P F + + EN P Sbjct: 194 VRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSP 253 Query: 272 IGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK 331 +G ++ + A D DEG N ++ Y+ + + + ID G + Q+D E Sbjct: 254 VGTLLLDLNATDPDEGANGKIVYSFSSH-VSPKIMETFKIDSERGHLTLFKQVDYEITKS 312 Query: 332 YQLLVTATDGGDPPRSATA-------TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 Y++ V A D G P S A PG+ E+ + P Sbjct: 313 YEIDVQAQDLG--PNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEGDPIDT 370 Query: 385 VVTLTATDADEDNRLHYEITGG-NTRGRFSI--TSQNGRGLITVAQPLDFKQERRYVLTV 441 V L D+D+ L+ EI + G F + T +N ++T A LD ++ Y LTV Sbjct: 371 FVALVRVQ-DKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTNAT-LDREKRSEYSLTV 428 Query: 442 SATDSGGRSDTAMVQ--INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499 A D G S + + + I D N+ P F+ + Y + E+ G + V+ATD D+G Sbjct: 429 IAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLG 488 Query: 500 INAQITYS-LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558 N Q+TY+ L S I ++ + I+P GAI ++ D E +S V ARDGG Sbjct: 489 ENGQVTYTILESFILGSSITTY---VTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGS 545 Query: 559 PS-LSDTTDVEISVVDVNDNEPV-----FKQQLYTANIMEDALVGTSVSQVGATDADVGL 612 P L T V ++++D NDN PV + I + A G V+++ A D D G+ Sbjct: 546 PKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAESGFHVTRIRAIDRDSGV 605 Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672 N + + EE F+IDP S I TN ++D +L + D G P + V+ Sbjct: 606 NAELSCAI-VAGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQLHTKVL 664 Query: 673 VHIKIEDINDS 683 + I + +S Sbjct: 665 LKCMIFEYAES 675 Score = 189 bits (460), Expect = 1e-45 Identities = 163/578 (28%), Positives = 261/578 (45%), Gaps = 57/578 (9%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 H ++ VLD ND+SP F + E A+ GT + A D D+G+N+ +T L Sbjct: 115 HIEVEVLDINDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENS--LHTYSLSAN 172 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGA-LLTRASLDREKVARYTVLVKATDQASPV 126 D N E R DG A L+ LDRE + Y + + A+D P Sbjct: 173 DFFNIEVRT--------------RTDGAKYAELIVVRELDRELKSSYELQLTASDMGVP- 217 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 + S ++ + ++I D NDN P F +++Y + + E+ V ++ + ATD D GAN Sbjct: 218 --QRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSPV--GTLLLDLNATDPDEGANGK 273 Query: 187 IRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 I Y+ + F IDS G ++L K +DYE +SY + ++AQD G S ++ Sbjct: 274 IVYSFSSHVSPKIMETFKIDSERGHLTLFKQVDYEITKSYEIDVQAQDLGPNSIPAHCKI 333 Query: 244 LINIRDVNDNAPRFYTSLF---QESVS---ENVPIGYSIVRVQAYDADEGVNAELTYTMT 297 +I + DVNDN P +L +E +S E PI + V+ D D G+N E+ + Sbjct: 334 IIKVVDVNDNKPEININLMSPGKEEISYIFEGDPIDTFVALVRVQDKDSGLNGEIVCKLH 393 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357 G+ L T + + + T+ LDRE +++Y L V A D G P S Sbjct: 394 GH---GHFKLQKTYE-NNYLILTNATLDREKRSEYSLTVIAEDRGTPSLSTVKHFTVQIN 449 Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRG---RF 412 F +YE ++E+ PG + T+TATD D E+ ++ Y I G Sbjct: 450 DINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLGENGQVTYTILESFILGSSITT 509 Query: 413 SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR----SDTAMVQINITDANNYAPV 468 +T G I + D ++ + V A D G S+T +V + I D N+ PV Sbjct: 510 YVTIDPSNGAIYALRIFDHEEVSQITFVVEARDGGSPKQLVSNTTVV-LTIIDENDNVPV 568 Query: 469 -----FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523 N ++ + A G V + A D D G+NA+++ ++ + + Sbjct: 569 VIGPALRNNTAEITIPKGAESGFHVTRIRAIDRDSGVNAELSCAI-------VAGNEENI 621 Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSL 561 F+I+P++ I TN +D + + L+V +D G P L Sbjct: 622 FIIDPRSCDIHTNVSMDSVPYTEWELSVIIQDKGNPQL 659 Score = 184 bits (449), Expect = 2e-44 Identities = 152/498 (30%), Positives = 240/498 (48%), Gaps = 36/498 (7%) Query: 373 VELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSI-TSQNGRGL--ITVAQP 428 +E++E GT + +A D D +N LH N + T +G + V + Sbjct: 137 IEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSANDFFNIEVRTRTDGAKYAELIVVRE 196 Query: 429 LDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD + + Y L ++A+D G RS +++++I+I+D+N+ +P FE Y + E++P+GT Sbjct: 197 LDRELKSSYELQLTASDMGVPQRSGSSILKISISDSNDNSPAFEQQSYIIQLLENSPVGT 256 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 +L ++ATD D G N +I YS SS +S + + + F I+ + G +T K +D E Sbjct: 257 LLLDLNATDPDEGANGKIVYSFSSHVSPKIM----ETFKIDSERGHLTLFKQVDYEITKS 312 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT------ANIMEDALVGTSV 600 Y + V A+D G S+ + I VVDVNDN+P L + + I E + T V Sbjct: 313 YEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMSPGKEEISYIFEGDPIDTFV 372 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA---SGVIRTNKALDRESVATHDLKA 657 + V D D GLNG I +L G F + + +I TN LDRE + + L Sbjct: 373 ALVRVQDKDSGLNGEIVCKL----HGHGHFKLQKTYENNYLILTNATLDREKRSEYSLTV 428 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 +A D GTP S+ ++I DIND+PP F+ F ISEN+ G I + A DPD G Sbjct: 429 IAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSPGAYITTVTATDPDLG 488 Query: 718 PNAVVHYSI-KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASP- 772 N V Y+I + +S + + + D+E + V+ A SP Sbjct: 489 ENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEV-SQITFVVEARDGGSPK 547 Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-----FGRVPAYDAD--VTD 825 L ++ V + + D NDN PV+ + N + P G R+ A D D V Sbjct: 548 QLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAESGFHVTRIRAIDRDSGVNA 607 Query: 826 KLQYRILSGNNANLILLN 843 +L I++GN N+ +++ Sbjct: 608 ELSCAIVAGNEENIFIID 625 Score = 151 bits (367), Expect = 2e-34 Identities = 121/414 (29%), Positives = 196/414 (47%), Gaps = 29/414 (7%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 +++ + D N+ +P F + + E A +GT + + SA D DVG N+ TYSLS+ N Sbjct: 116 IEVEVLDINDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSA---N 172 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 + + + + + LDRE S Y L +TA D GVP S ++ ++IS+ D Sbjct: 173 DFFNIEVRTRTDGAKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDS 232 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY----ELDPKDREEGSF 630 NDN P F+QQ Y ++E++ VGT + + ATD D G NG+I Y + PK E +F Sbjct: 233 NDNSPAFEQQSYIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIME--TF 290 Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690 ID G + K +D E ++++ A D G + + IK+ D+ND+ P + Sbjct: 291 KIDSERGHLTLFKQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININ 350 Query: 691 CLT------FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD 744 ++ YI E PI T + +R D D G N + + G F L+ + + Sbjct: 351 LMSPGKEEISYIFEGDPIDTFVALVRVQDKDSGLNGEIVCKLHG---HGHFKLQ-KTYEN 406 Query: 745 KAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801 ++T LD E R +Y L + A +P L + + D+NDN P + + F Sbjct: 407 NYLILTNATLDREK-RSEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEF 465 Query: 802 NNYKDCFPVGPFGRVPAYDADVTD--KLQYRILSGNNANLILLNETTGSMTLSP 853 ++ P V A D D+ + ++ Y IL + IL + T +T+ P Sbjct: 466 VISENNSPGAYITTVTATDPDLGENGQVTYTILE----SFILGSSITTYVTIDP 515 >UniRef50_Q60H59 Cluster: Protocadherin2-gamma-c6-sCP1; n=37; Clupeocephala|Rep: Protocadherin2-gamma-c6-sCP1 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 966 Score = 217 bits (531), Expect = 3e-54 Identities = 174/607 (28%), Positives = 271/607 (44%), Gaps = 30/607 (4%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIH---VNIIDDNDN 146 F +D G L+ +DRE T+ ++ P+ + + +H + I D NDN Sbjct: 72 FSVDSGKGDLVVNGRIDRE-----TLCGQSASCLMPLQIVIENPLQLHRVEIEIQDINDN 126 Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206 P F K + + E V + A D DV +NS Y + N + ++ +L Sbjct: 127 PPTFHTKDVILKISE--LVAPGTRFSLESAEDLDVSSNSLKTYT-LNNNDFFRLNVKTLK 183 Query: 207 G-----DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261 ++ + K LD E+ + L++ A DGG+P +S T+ L I ++D+NDN P+F + Sbjct: 184 NGRKVPELVVEKALDREKQSIHELILTALDGGNPVKSGTSLLQIIVQDINDNEPKFEVAS 243 Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321 ++ SV E S+++++A D DEG+N E+ Y +V ++ +G + Sbjct: 244 YKASVVEKATFDLSVLKIKATDPDEGLNGEIEYLFA-AHTPESVRNVFRVNVETGEIKVI 302 Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381 G LD ET+ Y V A D G+P ++ + + E+ Sbjct: 303 GGLDYETKKSYTFDVCAKDKGNPELEGQSSVQIDIIDENDNPPEIILTSLPSPVPENATV 362 Query: 382 GTPVVTLTATDADEDNRLHYEITGGNTRGRFSITS-QNGRGLITVAQPLDFKQERRYVLT 440 GT V + D D N E+T ITS +N LIT + LD + Y + Sbjct: 363 GTVVALINVKDLDSGNNGKVELTISTGAPFKIITSFENHYSLITDSF-LDRELNSEYNIE 421 Query: 441 VSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498 + A D G S T V + + D N+ +PVF + Y + E+ G ++ VSATDSD Sbjct: 422 ILARDLGVPSLITTKAVNVKVLDVNDNSPVFSQSSYNVYINENNLAGFSLFSVSATDSDQ 481 Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558 NA +TYS+ N A F IN + G I + D E M + V A+D G Sbjct: 482 DKNAMLTYSVLDLSPNHVPA--SSYFYINSENGTIYSMSSFDYEKMKLISIVVQAKDQGS 539 Query: 559 PSLSDTTDVEISVVDVNDNEP-VFKQQLYTANIMED-----ALVGTSVSQVGATDADVGL 612 PSLS V + ++D NDN P V ++ A G V++V A DAD G Sbjct: 540 PSLSSNATVHVFILDQNDNAPAVIYPSTSMGSVSHQRMPRFAKAGHLVTKVTAVDADSGH 599 Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672 N + Y L + + F ++ +G +RT +A+ ++ L D G P QS+TV Sbjct: 600 NAWLFYRL-AEATDASLFSVNLHTGEVRTKRAVSEHDDSSQRLVLEIKDNGDPIQSTTVT 658 Query: 673 VHIKIED 679 V I IED Sbjct: 659 VDILIED 665 Score = 211 bits (516), Expect = 2e-52 Identities = 173/628 (27%), Positives = 285/628 (45%), Gaps = 35/628 (5%) Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDG-GSPS 236 D+ + + I + + FS+DS GD+ + +D E + +S ++ Q +P Sbjct: 52 DISDIAERKLRIASESNRQYFSVDSGKGDLVVNGRIDRETLCGQSASCLMPLQIVIENPL 111 Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 + + + I I+D+NDN P F+T +SE V G A D D N+ TYT+ Sbjct: 112 QLHRVE--IEIQDINDNPPTFHTKDVILKISELVAPGTRFSLESAEDLDVSSNSLKTYTL 169 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 + D+ + + + LDRE Q+ ++L++TA DGG+P +S T+ Sbjct: 170 NNNDFFRLNVKTLKNGRKVPELVVEKALDREKQSIHELILTALDGGNPVKSGTSLLQIIV 229 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI---TGGNTRGR 411 F Y+ + E V+ + ATD DE + + Y T + R Sbjct: 230 QDINDNEPKFEVASYKASVVEKATFDLSVLKIKATDPDEGLNGEIEYLFAAHTPESVRNV 289 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVF 469 F + + G I V LD++ ++ Y V A D G + VQI+I D N+ P Sbjct: 290 FRVNVETGE--IKVIGGLDYETKKSYTFDVCAKDKGNPELEGQSSVQIDIIDENDNPPEI 347 Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 + V E+A +GT V +++ D D G N ++ ++S+ + + + + Sbjct: 348 ILTSLPSPVPENATVGTVVALINVKDLDSGNNGKVELTISTGAPFKIITSFENHY----- 402 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589 ++ T+ LDRE S Y + + ARD GVPSL T V + V+DVNDN PVF Q Y Sbjct: 403 --SLITDSFLDRELNSEYNIEILARDLGVPSLITTKAVNVKVLDVNDNSPVFSQSSYNVY 460 Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHY---ELDPKDREEGS-FVIDPASGVIRTNKAL 645 I E+ L G S+ V ATD+D N + Y +L P S F I+ +G I + + Sbjct: 461 INENNLAGFSLFSVSATDSDQDKNAMLTYSVLDLSPNHVPASSYFYINSENGTIYSMSSF 520 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP--VFESDCLTFYISENSP-- 701 D E + + A D G+P SS VH+ I D ND+ P ++ S + + P Sbjct: 521 DYEKMKLISIVVQAKDQGSPSLSSNATVHVFILDQNDNAPAVIYPSTSMGSVSHQRMPRF 580 Query: 702 --IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP 759 G + ++ A D D G NA + Y + D++ FS+ G + + +++ Sbjct: 581 AKAGHLVTKVTAVDADSGHNAWLFYRLAEATDASLFSVNLHTGEVRTKRAVS---EHDDS 637 Query: 760 RKKYELVIRAASPPLWN-DVRVEILVTD 786 ++ L I+ P+ + V V+IL+ D Sbjct: 638 SQRLVLEIKDNGDPIQSTTVTVDILIED 665 Score = 191 bits (465), Expect = 3e-46 Identities = 152/536 (28%), Positives = 259/536 (48%), Gaps = 25/536 (4%) Query: 373 VELAEDEPPGTPVVTLTATDAD-EDNRLHYEITGGNTRGRFSI-TSQNGRGL--ITVAQP 428 ++++E PGT +A D D N L N R ++ T +NGR + + V + Sbjct: 137 LKISELVAPGTRFSLESAEDLDVSSNSLKTYTLNNNDFFRLNVKTLKNGRKVPELVVEKA 196 Query: 429 LDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD +++ + L ++A D G +S T+++QI + D N+ P FE A Y ASV E A Sbjct: 197 LDREKQSIHELILTALDGGNPVKSGTSLLQIIVQDINDNEPKFEVASYKASVVEKATFDL 256 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 +VL + ATD D G+N +I Y ++ + E+V + F +N +TG I LD ET Sbjct: 257 SVLKIKATDPDEGLNGEIEYLFAAH-TPESVRN---VFRVNVETGEIKVIGGLDYETKKS 312 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y V A+D G P L + V+I ++D NDN P + + E+A VGT V+ + Sbjct: 313 YTFDVCAKDKGNPELEGQSSVQIDIIDENDNPPEIILTSLPSPVPENATVGTVVALINVK 372 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D D G NG++ + + + +I T+ LDRE + ++++ +A D G P Sbjct: 373 DLDSGNNGKVELTISTGAPFKIITSFENHYSLI-TDSFLDRELNSEYNIEILARDLGVPS 431 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 +T V++K+ D+ND+ PVF YI+EN+ G ++ + A D D+ NA++ YS+ Sbjct: 432 LITTKAVNVKVLDVNDNSPVFSQSSYNVYINENNLAGFSLFSVSATDSDQDKNAMLTYSV 491 Query: 727 KGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEI 782 ++ S S+ + +M DYE K +V++A SP L ++ V + Sbjct: 492 LDLSPNHVPASSYFYINSENGTIYSMSSFDYEK-MKLISIVVQAKDQGSPSLSSNATVHV 550 Query: 783 LVTDVNDNAPVM----KDFQIIFNNYKDCFPVGP--FGRVPAYDADVTDK--LQYRILSG 834 + D NDNAP + + + F +V A DAD L YR+ Sbjct: 551 FILDQNDNAPAVIYPSTSMGSVSHQRMPRFAKAGHLVTKVTAVDADSGHNAWLFYRLAEA 610 Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEE 890 +A+L +N TG + ++ + + + + D + I++ ++V ++ E+ Sbjct: 611 TDASLFSVNLHTGEVRTKRAVSEHDDSSQRLVLEIKDNGDPIQS-TTVTVDILIED 665 Score = 176 bits (428), Expect = 8e-42 Identities = 165/596 (27%), Positives = 252/596 (42%), Gaps = 53/596 (8%) Query: 4 PFCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 P +H+ +I + D ND+ P F + + E + GT A D D+ N+ YT Sbjct: 110 PLQLHRVEIEIQDINDNPPTFHTKDVILKISELVAPGTRFSLESAEDLDVSSNSLKTYT- 168 Query: 63 ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122 LN D + V L+ +LDREK + + +++ A D Sbjct: 169 -------LNNNDFFRLNVKTLKNGRKV-------PELVVEKALDREKQSIHELILTALDG 214 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 +PV S T+ + + + D NDN P+F +Y SV E T + + KIKATD D G Sbjct: 215 GNPVK---SGTSLLQIIVQDINDNEPKFEVASYKASVVE--KATFDLSVLKIKATDPDEG 269 Query: 183 ANSAIRY---AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239 N I Y A + + F ++ +G++ ++ LDYE +SY + A+D G+P Sbjct: 270 LNGEIEYLFAAHTPESVRNVFRVNVETGEIKVIGGLDYETKKSYTFDVCAKDKGNPELEG 329 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 + + I+I D NDN P + V EN +G + + D D G N ++ T++ Sbjct: 330 QSSVQIDIIDENDNPPEIILTSLPSPVPENATVGTVVALINVKDLDSGNNGKVELTIS-- 387 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 TG IT + T LDRE ++Y + + A D G P T Sbjct: 388 --TGAPFKIITSFENHYSLITDSFLDRELNSEYNIEILARDLGVPSLITTKAVNVKVLDV 445 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR--LHYEITGGN-----TRGRF 412 F Y V + E+ G + +++ATD+D+D L Y + + F Sbjct: 446 NDNSPVFSQSSYNVYINENNLAGFSLFSVSATDSDQDKNAMLTYSVLDLSPNHVPASSYF 505 Query: 413 SITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAP-VF 469 I S+N G I D+++ + + V A D G S A V + I D N+ AP V Sbjct: 506 YINSEN--GTIYSMSSFDYEKMKLISIVVQAKDQGSPSLSSNATVHVFILDQNDNAPAVI 563 Query: 470 ENAPYTASVFED-----APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524 + SV A G V V+A D+D G NA + Y L A A F Sbjct: 564 YPSTSMGSVSHQRMPRFAKAGHLVTKVTAVDADSGHNAWLFYRL-------AEATDASLF 616 Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580 +N TG + T + + S L + +D G P S T V+I + D +EPV Sbjct: 617 SVNLHTGEVRTKRAVSEHDDSSQRLVLEIKDNGDPIQSTTVTVDILIED-GFHEPV 671 >UniRef50_Q32PS9 Cluster: Pcdh1g18 protein; n=35; Clupeocephala|Rep: Pcdh1g18 protein - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 868 Score = 217 bits (530), Expect = 4e-54 Identities = 171/602 (28%), Positives = 280/602 (46%), Gaps = 28/602 (4%) Query: 92 IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151 +D +G L+ + +DRE++ + + + + V+I D NDN P F Sbjct: 58 LDKENGHLVIKNKIDREELCGEISACSVSFDV--ILENPMELYRVTVDIQDINDNSPAFL 115 Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN---TQMQFSID-SLSG 207 + + E + + + A D DVG N+ +Y + + +Q + D S + Sbjct: 116 KSKIEQEISELVLIGARFPLES--AVDPDVGVNALQKYTLQPTDHFKLNVQNAEDGSKNV 173 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 ++ L LD E+ + L++ A DGG P RS T + I I DVNDNAP F S ++ S+ Sbjct: 174 EIVLHSPLDREKKNHHSLILTAFDGGKPQRSATLHINIIILDVNDNAPVFSQSSYKTSIV 233 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 EN P ++RV A DADE + Y + T V +ID SG V +GQ+D E Sbjct: 234 ENAPKSTVVIRVSATDADESSHGIQYYF---EHATPTVKALFSIDADSGDVKVTGQIDYE 290 Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387 ++++ V A D G S+ M + ++ED PGT + Sbjct: 291 KHKQFKIKVKAKDHGGLTDSSEIIIDVIDVNDNKPKITIM--SFSSAVSEDAAPGTVIAM 348 Query: 388 LTATDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446 + D D DN N+ + + N L+T ++ LD +Q Y +T++A D Sbjct: 349 INVQDLDSGDNSKISCSIDLNSPFKIISSLTNYYNLVTDSE-LDREQTAEYNITITAVDG 407 Query: 447 GG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504 G S ++ + I+D N++AP F Y A + E+ P TT+L V A D D G NA++ Sbjct: 408 GNPPLSVKEILNLKISDVNDHAPQFVQESYNAFIAENNPPSTTILTVKAEDMDWGPNAKV 467 Query: 505 TYSL-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD 563 +Y L ++++ +A + IN ++G + K D E + + + V A+DGG P LS Sbjct: 468 SYFLIDADLNGAPLASY---ISINSESGVVYAEKSFDYEQLKSFKMQVKAQDGGSPPLSS 524 Query: 564 TTDVEISVVDVNDNEPVFKQQLYT-ANIMED-----ALVGTSVSQVGATDADVGLNGRIH 617 + I + D NDN P + T A+++ + A VG V++V A D D G N + Sbjct: 525 NVTLNIIIQDQNDNAPQVLYPVQTGASVVAEIVPRAADVGYLVTKVVAVDVDSGQNAWLS 584 Query: 618 YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 Y+L K + F + +G IRT + + + L V D G P +S+ V +++ + Sbjct: 585 YKLQ-KAADRALFEVGLQNGEIRTVRQVTDKDAVKQKLTVVVEDNGQPSRSAVVSINVAV 643 Query: 678 ED 679 D Sbjct: 644 AD 645 Score = 206 bits (502), Expect = 9e-51 Identities = 164/582 (28%), Positives = 281/582 (48%), Gaps = 57/582 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +++ D ND+SP F + E + E G A D D+G NA +YT++ L Sbjct: 102 VDIQDINDNSPAFLKSKIEQEISELVLIGARFPLESAVDPDVGVNALQKYTLQPTDHFKL 161 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N ++A +D ++ ++ + LDREK +++++ A D P Sbjct: 162 NVQNA-----------ED----GSKNVEIVLHSPLDREKKNHHSLILTAFDGGKP----- 201 Query: 131 SSTATIHVNII--DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 +AT+H+NII D NDN P FS+ +Y S+ E + + V+ ++ ATDAD ++ Sbjct: 202 QRSATLHINIIILDVNDNAPVFSQSSYKTSIVE--NAPKSTVVIRVSATDADESSHGIQY 259 Query: 189 YAIIGGNT-QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 Y T + FSID+ SGDV + +DYE+ + +++ ++A+D G +++++++I++ Sbjct: 260 YFEHATPTVKALFSIDADSGDVKVTGQIDYEKHKQFKIKVKAKDHG--GLTDSSEIIIDV 317 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 DVNDN P+ F +VSE+ G I + D D G N++++ ++ D + Sbjct: 318 IDVNDNKPKITIMSFSSAVSEDAAPGTVIAMINVQDLDSGDNSKISCSI---DLNSPFKI 374 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 ++ V T +LDRE A+Y + +TA DGG+PP S F+ Sbjct: 375 ISSLTNYYNLV-TDSELDREQTAEYNITITAVDGGNPPLSVKEILNLKISDVNDHAPQFV 433 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHY-----EITGGNTRGRFSITSQNGR 420 Y +AE+ PP T ++T+ A D D + ++ Y ++ G SI S++ Sbjct: 434 QESYNAFIAENNPPSTTILTVKAEDMDWGPNAKVSYFLIDADLNGAPLASYISINSES-- 491 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYAP-VFENAPYTAS 477 G++ + D++Q + + + V A D G ++ V +N I D N+ AP V AS Sbjct: 492 GVVYAEKSFDYEQLKSFKMQVKAQDGGSPPLSSNVTLNIIIQDQNDNAPQVLYPVQTGAS 551 Query: 478 VFED-----APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 V + A +G V V A D D G NA ++Y L + ++ A+ F + Q G Sbjct: 552 VVAEIVPRAADVGYLVTKVVAVDVDSGQNAWLSYKL-QKAADRAL------FEVGLQNGE 604 Query: 533 I-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 I T ++ D++ + LTV D G PS S + ++V D Sbjct: 605 IRTVRQVTDKDAVK-QKLTVVVEDNGQPSRSAVVSINVAVAD 645 Score = 189 bits (461), Expect = 8e-46 Identities = 120/376 (31%), Positives = 196/376 (52%), Gaps = 16/376 (4%) Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480 I + PLD +++ + L ++A D G RS T + I I D N+ APVF + Y S+ E Sbjct: 175 IVLHSPLDREKKNHHSLILTAFDGGKPQRSATLHINIIILDVNDNAPVFSQSSYKTSIVE 234 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 +AP T V+ VSATD+D + Y + + +A+ F I+ +G + +D Sbjct: 235 NAPKSTVVIRVSATDADESSHGIQYYFEHATPTVKAL------FSIDADSGDVKVTGQID 288 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 E + + V A+D G L+D++++ I V+DVNDN+P +++ + EDA GT + Sbjct: 289 YEKHKQFKIKVKAKDHG--GLTDSSEIIIDVIDVNDNKPKITIMSFSSAVSEDAAPGTVI 346 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 + + D D G N +I +D + + ++ T+ LDRE A +++ A+ Sbjct: 347 AMINVQDLDSGDNSKISCSIDLNSPFKIISSLTNYYNLV-TDSELDREQTAEYNITITAV 405 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 DGG PP S I+++KI D+ND P F + +I+EN+P TTI ++A D D GPNA Sbjct: 406 DGGNPPLSVKEILNLKISDVNDHAPQFVQESYNAFIAENNPPSTTILTVKAEDMDWGPNA 465 Query: 721 VVHYSIKGGD-DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776 V Y + D + + S+ + DYE K +++ ++A SPPL + Sbjct: 466 KVSYFLIDADLNGAPLASYISINSESGVVYAEKSFDYEQ-LKSFKMQVKAQDGGSPPLSS 524 Query: 777 DVRVEILVTDVNDNAP 792 +V + I++ D NDNAP Sbjct: 525 NVTLNIIIQDQNDNAP 540 Score = 184 bits (449), Expect = 2e-44 Identities = 148/473 (31%), Positives = 222/473 (46%), Gaps = 40/473 (8%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 +H I +LD ND++PVF Y+ S+ E A T V+ + ATD D + ++Y E T Sbjct: 207 LHINIIILDVNDNAPVFSQSSYKTSIVENAPKSTVVIRVSATDADESSHG-IQYYFEHAT 265 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 V+ +F ID SG + +D EK ++ + VKA D Sbjct: 266 P-----------------TVKALFSIDADSGDVKVTGQIDYEKHKQFKIKVKAKDHGG-- 306 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 L+ ++ I +++ID NDN P+ + +++ +V ED + VIA I D D G NS Sbjct: 307 ---LTDSSEIIIDVIDVNDNKPKITIMSFSSAVSEDAA--PGTVIAMINVQDLDSGDNSK 361 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 I +I N+ + I SL+ +LV LD EQ Y + I A DGG+P S L Sbjct: 362 ISCSI-DLNSPFKI-ISSLTNYYNLVTDSELDREQTAEYNITITAVDGGNPPLSVKEILN 419 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG- 303 + I DVND+AP+F + ++EN P +I+ V+A D D G NA+++Y + D D G Sbjct: 420 LKISDVNDHAPQFVQESYNAFIAENNPPSTTILTVKAEDMDWGPNAKVSYFLIDADLNGA 479 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 + I+I+ SG VY D E +++ V A DGG PP S+ T Sbjct: 480 PLASYISINSESGVVYAEKSFDYEQLKSFKMQVKAQDGGSPPLSSNVTLNIIIQDQNDNA 539 Query: 364 XXFM-PGQYEVELAEDEPP-----GTPVVTLTATDADEDNR--LHYEITGGNTRGRFSIT 415 + P Q + + P G V + A D D L Y++ R F + Sbjct: 540 PQVLYPVQTGASVVAEIVPRAADVGYLVTKVVAVDVDSGQNAWLSYKLQKAADRALFEVG 599 Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468 QNG + TV Q D K + LTV D+G S +A+V IN+ A+++ V Sbjct: 600 LQNGE-IRTVRQVTD-KDAVKQKLTVVVEDNGQPSRSAVVSINVAVADSFPEV 650 Score = 144 bits (350), Expect = 2e-32 Identities = 113/345 (32%), Positives = 164/345 (47%), Gaps = 21/345 (6%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 V ++I D N+ +P F + + E IG + SA D DVG+NA Y+L Sbjct: 100 VTVDIQDINDNSPAFLKSKIEQEISELVLIGARFPLESAVDPDVGVNALQKYTLQP---- 155 Query: 515 EAVAHHDQQFVINPQTGA----ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570 H + V N + G+ I + LDRE + + L +TA DGG P S T + I Sbjct: 156 ---TDHFKLNVQNAEDGSKNVEIVLHSPLDREKKNHHSLILTAFDGGKPQRSATLHINII 212 Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630 ++DVNDN PVF Q Y +I+E+A T V +V ATDAD +G +Y + F Sbjct: 213 ILDVNDNAPVFSQSSYKTSIVENAPKSTVVIRVSATDADESSHGIQYYFEHATPTVKALF 272 Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690 ID SG ++ +D E +K A D G SS +I I + D+ND+ P Sbjct: 273 SIDADSGDVKVTGQIDYEKHKQFKIKVKAKDHGGLTDSSEII--IDVIDVNDNKPKITIM 330 Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750 + +SE++ GT I I D D G N+ + SI D NS ++ LVT Sbjct: 331 SFSSAVSEDAAPGTVIAMINVQDLDSGDNSKISCSI----DLNSPFKIISSLTNYYNLVT 386 Query: 751 MVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792 +LD E +Y + I A +PPL + + ++DVND+AP Sbjct: 387 DSELDREQ-TAEYNITITAVDGGNPPLSVKEILNLKISDVNDHAP 430 Score = 62.5 bits (145), Expect = 2e-07 Identities = 56/203 (27%), Positives = 85/203 (41%), Gaps = 6/203 (2%) Query: 632 IDPASGVIRTNKALDRESVATH-DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690 +D +G + +DRE + +V+ D V + I+DIND+ P F Sbjct: 58 LDKENGHLVIKNKIDREELCGEISACSVSFDVILENPMELYRVTVDIQDINDNSPAFLKS 117 Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750 + ISE IG A DPD G NA+ Y+++ D GS E+V Sbjct: 118 KIEQEISELVLIGARFPLESAVDPDVGVNALQKYTLQPTDHFKLNVQNAEDGSKNVEIVL 177 Query: 751 MVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC 807 LD E + + L++ A P + + I++ DVNDNAPV + ++ Sbjct: 178 HSPLDREK-KNHHSLILTAFDGGKPQRSATLHINIIILDVNDNAPVFSQSSYKTSIVENA 236 Query: 808 FPVGPFGRVPAYDADVTDK-LQY 829 RV A DAD + +QY Sbjct: 237 PKSTVVIRVSATDADESSHGIQY 259 >UniRef50_UPI00006614A3 Cluster: Homolog of Brachydanio rerio "Protocadherin2-gamma-v5-A.; n=3; Clupeocephala|Rep: Homolog of Brachydanio rerio "Protocadherin2-gamma-v5-A. - Takifugu rubripes Length = 715 Score = 216 bits (527), Expect = 8e-54 Identities = 171/559 (30%), Positives = 266/559 (47%), Gaps = 47/559 (8%) Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195 I V ++D ND+ P F + VS++ S A D DVG N+ Y + Sbjct: 122 ITVEVLDINDHAPVFPNQDKHVSLEISESALTGTQFPLQGADDMDVGQNALQNYVLSQNE 181 Query: 196 TQMQFSIDSLSG----DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251 + + G ++ L K LD E+ L + A DGG+P RS T + I + D N Sbjct: 182 NFILKQHANPDGSKYVEMVLQKPLDRERHPHLSLKLIAVDGGTPQRSGTVNIDITVLDAN 241 Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311 DN P F S+++ S+ EN IG ++V V A DAD G+ +TY+++ K G ++ TI Sbjct: 242 DNVPVFNQSVYKASIMENTKIGTNVVTVNATDADSGIYGLITYSLS-KMKGGAAEI-FTI 299 Query: 312 DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371 D +G + SG +D E KY++ V A D G T T + Sbjct: 300 DESTGAITVSGPIDYEKDRKYEVRVEARDRG----GLTGTSKVV---------------F 340 Query: 372 EVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ--NGRGLITVAQPL 429 +V D PP V+ + D+D++ ++ + + + F I S N LI+ Q Sbjct: 341 DVSDVNDNPP---VINVIDADSDKNGQIKCSL---DRKLPFKIESSLTNYYNLIS-DQFF 393 Query: 430 DFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 D + +Y +TV+ATDSG S + + + I+D N+ AP+FE Y+A + E+ GT+ Sbjct: 394 DRESVSKYNITVTATDSGTPPLSTSTTLHLIISDVNDNAPLFEKQSYSAYIVENNSPGTS 453 Query: 488 VLVVSATDSDVGINAQITYSL-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 + VSA DSD NA+I+Y L + IS ++ + +N + G I+ + D E + Sbjct: 454 IFTVSARDSDWNQNARISYILEETHISGSPISSY---LSLNSENGVISAARSFDYEQIKE 510 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM------EDALVGTSV 600 + V A+DGG P LS V+I + D NDN P + T M A VG V Sbjct: 511 LQIVVKAQDGGSPPLSSNVSVKILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYLV 570 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 ++V A D D G N + Y+L K + F + +G IRT + + + L + Sbjct: 571 TKVVAVDVDSGQNAWLSYKLQ-KATDRALFEVGLQNGEIRTIRQVTDKDAVKQRLSVIVE 629 Query: 661 DGGTPPQSSTVIVHIKIED 679 D G P +S+TVIV++ + D Sbjct: 630 DNGQPSRSATVIVNVAVAD 648 Score = 190 bits (462), Expect = 6e-46 Identities = 151/519 (29%), Positives = 239/519 (46%), Gaps = 51/519 (9%) Query: 242 QLLINIRDVNDNAPRFYTSLFQES--VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 ++ + + D+ND+AP F S +SE+ G A D D G NA Y ++ Sbjct: 121 RITVEVLDINDHAPVFPNQDKHVSLEISESALTGTQFPLQGADDMDVGQNALQNYVLSQN 180 Query: 300 DYTGNVDLPITIDPR-SGWVYTSGQ--LDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 + N L +P S +V Q LDRE L + A DGG P RS T Sbjct: 181 E---NFILKQHANPDGSKYVEMVLQKPLDRERHPHLSLKLIAVDGGTPQRSGTVNIDITV 237 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSI 414 F Y+ + E+ GT VVT+ ATDAD + Y ++ Sbjct: 238 LDANDNVPVFNQSVYKASIMENTKIGTNVVTVNATDADSGIYGLITYSLSKMKGGAAEIF 297 Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPY 474 T G ITV+ P+D++++R+Y + V A D GG + T+ V +++D N+ P Sbjct: 298 TIDESTGAITVSGPIDYEKDRKYEVRVEARDRGGLTGTSKVVFDVSDVNDNPP------- 350 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 V++ D+D N QI SL ++ + + + + Sbjct: 351 ---------------VINVIDADSDKNGQIKCSLDRKLPFKIESSLTNYY-------NLI 388 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 +++ DRE++S Y +TVTA D G P LS +T + + + DVNDN P+F++Q Y+A I+E+ Sbjct: 389 SDQFFDRESVSKYNITVTATDSGTPPLSTSTTLHLIISDVNDNAPLFEKQSYSAYIVENN 448 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV-----IDPASGVIRTNKALDRES 649 GTS+ V A D+D N RI Y L+ + GS + ++ +GVI ++ D E Sbjct: 449 SPGTSIFTVSARDSDWNQNARISYILE-ETHISGSPISSYLSLNSENGVISAARSFDYEQ 507 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF------ESDCLTFYISENSPIG 703 + + A DGG+PP SS V V I I+D ND+PP + + ++ +G Sbjct: 508 IKELQIVVKAQDGGSPPLSSNVSVKILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVG 567 Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 + ++ A D D G NA + Y ++ D F + + G Sbjct: 568 YLVTKVVAVDVDSGQNAWLSYKLQKATDRALFEVGLQNG 606 Score = 181 bits (441), Expect = 2e-43 Identities = 131/376 (34%), Positives = 190/376 (50%), Gaps = 37/376 (9%) Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480 + + +PLD ++ L + A D G RS T + I + DAN+ PVF + Y AS+ E Sbjct: 199 MVLQKPLDRERHPHLSLKLIAVDGGTPQRSGTVNIDITVLDANDNVPVFNQSVYKASIME 258 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 + IGT V+ V+ATD+D GI ITYSLS A + F I+ TGAIT + +D Sbjct: 259 NTKIGTNVVTVNATDADSGIYGLITYSLSKMKGGAA-----EIFTIDESTGAITVSGPID 313 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 E Y + V ARD G L+ T+ V V DVNDN PV Sbjct: 314 YEKDRKYEVRVEARDRG--GLTGTSKVVFDVSDVNDNPPV-------------------- 351 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 + DAD NG+I LD K + + +I +++ DRESV+ +++ A Sbjct: 352 --INVIDADSDKNGQIKCSLDRKLPFKIESSLTNYYNLI-SDQFFDRESVSKYNITVTAT 408 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 D GTPP S++ +H+ I D+ND+ P+FE + YI EN+ GT+I + A D D NA Sbjct: 409 DSGTPPLSTSTTLHLIISDVNDNAPLFEKQSYSAYIVENNSPGTSIFTVSARDSDWNQNA 468 Query: 721 VVHYSIKGGDDSNS-FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776 + Y ++ S S S S+ + DYE K+ ++V++A SPPL + Sbjct: 469 RISYILEETHISGSPISSYLSLNSENGVISAARSFDYEQI-KELQIVVKAQDGGSPPLSS 527 Query: 777 DVRVEILVTDVNDNAP 792 +V V+IL+ D NDN P Sbjct: 528 NVSVKILIQDQNDNPP 543 Score = 173 bits (422), Expect = 4e-41 Identities = 162/595 (27%), Positives = 264/595 (44%), Gaps = 87/595 (14%) Query: 4 PFCIHQ-QINVLDCNDHSPVFEMQQYEAS--VREGASSGTTVLTLKATDQDIGKNAEVEY 60 P +H+ + VLD NDH+PVF Q S + E A +GT A D D+G+NA Y Sbjct: 116 PLELHRITVEVLDINDHAPVFPNQDKHVSLEISESALTGTQFPLQGADDMDVGQNALQNY 175 Query: 61 TIE----LVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVL 116 + + NP+ + ++ + LDRE+ ++ Sbjct: 176 VLSQNENFILKQHANPDGSKYVE-------------------MVLQKPLDRERHPHLSLK 216 Query: 117 VKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKA 176 + A D +P + S T I + ++D NDN P F++ Y S+ E+ + N + + A Sbjct: 217 LIAVDGGTP---QRSGTVNIDITVLDANDNVPVFNQSVYKASIMENTKIGTN--VVTVNA 271 Query: 177 TDADVGANSAIRYAI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS 234 TDAD G I Y++ + G F+ID +G +++ +DYE+ R Y + + A+D G Sbjct: 272 TDADSGIYGLITYSLSKMKGGAAEIFTIDESTGAITVSGPIDYEKDRKYEVRVEARDRG- 330 Query: 235 PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294 + T++++ ++ DVNDN P ++ V DAD N ++ Sbjct: 331 -GLTGTSKVVFDVSDVNDNPP--------------------VINV--IDADSDKNGQIKC 367 Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATDGGDPPRSATATXX 353 ++ D+ ++ +T + + S Q DRE+ +KY + VTATD G PP S + T Sbjct: 368 SL-DRKLPFKIESSLT----NYYNLISDQFFDRESVSKYNITVTATDSGTPPLSTSTTLH 422 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHY-----EITGG 406 F Y + E+ PGT + T++A D+D ++ R+ Y I+G Sbjct: 423 LIISDVNDNAPLFEKQSYSAYIVENNSPGTSIFTVSARDSDWNQNARISYILEETHISGS 482 Query: 407 NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANN 464 S+ S+N G+I+ A+ D++Q + + V A D G S V+I I D N+ Sbjct: 483 PISSYLSLNSEN--GVISAARSFDYEQIKELQIVVKAQDGGSPPLSSNVSVKILIQDQND 540 Query: 465 YAPVFENAPYTAS------VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518 P T V A +G V V A D D G NA ++Y L + ++ A+ Sbjct: 541 NPPQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQNAWLSYKL-QKATDRAL- 598 Query: 519 HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 F + Q G I T + + + L+V D G PS S T V ++V D Sbjct: 599 -----FEVGLQNGEIRTIRQVTDKDAVKQRLSVIVEDNGQPSRSATVIVNVAVAD 648 Score = 140 bits (339), Expect = 5e-31 Identities = 128/474 (27%), Positives = 208/474 (43%), Gaps = 63/474 (13%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 ++ I VLD ND+ PVF Y+AS+ E GT V+T+ ATD D G + Y++ + Sbjct: 231 VNIDITVLDANDNVPVFNQSVYKASIMENTKIGTNVVTVNATDADSGIYGLITYSLSKMK 290 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 ++F ID +GA+ +D EK +Y V V+A D+ Sbjct: 291 GGAA-----------------EIFTIDESTGAITVSGPIDYEKDRKYEVRVEARDRGG-- 331 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 L+ T+ + ++ D V DNP + I DAD N Sbjct: 332 ---LTGTSKVVFDVSD----------------------VNDNPPV--INVIDADSDKNGQ 364 Query: 187 IRYAIIGGNTQMQFSIDS-LSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 I+ ++ + ++ F I+S L+ +L+ D E V Y + + A D G+P S +T L Sbjct: 365 IKCSL---DRKLPFKIESSLTNYYNLISDQFFDRESVSKYNITVTATDSGTPPLSTSTTL 421 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 + I DVNDNAP F + + EN G SI V A D+D NA ++Y + + +G Sbjct: 422 HLIISDVNDNAPLFEKQSYSAYIVENNSPGTSIFTVSARDSDWNQNARISYILEETHISG 481 Query: 304 N-VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 + + ++++ +G + + D E + Q++V A DGG PP S+ + Sbjct: 482 SPISSYLSLNSENGVISAARSFDYEQIKELQIVVKAQDGGSPPLSSNVSVKILIQDQNDN 541 Query: 363 XXXFM-PGQYEVELAEDEPP-----GTPVVTLTATDADEDNR--LHYEITGGNTRGRFSI 414 + P Q + + P G V + A D D L Y++ R F + Sbjct: 542 PPQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLQKATDRALFEV 601 Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468 QNG + T+ Q D K + L+V D+G S +A V +N+ A+++ V Sbjct: 602 GLQNGE-IRTIRQVTD-KDAVKQRLSVIVEDNGQPSRSATVIVNVAVADSFPEV 653 Score = 139 bits (337), Expect = 9e-31 Identities = 110/347 (31%), Positives = 163/347 (46%), Gaps = 38/347 (10%) Query: 455 VQINITDANNYAPVFENAPYTAS--VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512 + + + D N++APVF N S + E A GT + A D DVG NA Y LS Sbjct: 122 ITVEVLDINDHAPVFPNQDKHVSLEISESALTGTQFPLQGADDMDVGQNALQNYVLSQN- 180 Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572 N + H + + K LDRE L + A DGG P S T +++I+V+ Sbjct: 181 ENFILKQHANPD--GSKYVEMVLQKPLDRERHPHLSLKLIAVDGGTPQRSGTVNIDITVL 238 Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP-KDREEGSFV 631 D NDN PVF Q +Y A+IME+ +GT+V V ATDAD G+ G I Y L K F Sbjct: 239 DANDNVPVFNQSVYKASIMENTKIGTNVVTVNATDADSGIYGLITYSLSKMKGGAAEIFT 298 Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691 ID ++G I + +D E ++++ A D G +S V+ + D+ND+PPV Sbjct: 299 IDESTGAITVSGPIDYEKDRKYEVRVEARDRGGLTGTSKVV--FDVSDVNDNPPV----- 351 Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751 I D D N + S+ D F +E+ ++ L++ Sbjct: 352 -----------------INVIDADSDKNGQIKCSL---DRKLPFKIESSL-TNYYNLISD 390 Query: 752 VDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMK 795 D ES KY + + A +PPL + ++++DVNDNAP+ + Sbjct: 391 QFFDRESV-SKYNITVTATDSGTPPLSTSTTLHLIISDVNDNAPLFE 436 Score = 119 bits (287), Expect = 1e-24 Identities = 90/279 (32%), Positives = 136/279 (48%), Gaps = 16/279 (5%) Query: 526 INPQTGAITTNKLLDRETMSGYLLTVT-ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584 +N G + N+ +DRE + G + + + + + + + + + V+D+ND+ PVF Q Sbjct: 80 LNTDKGILVVNERIDREQLCGDVTPCSFSIEVILENPLELHRITVEVLDINDHAPVFPNQ 139 Query: 585 --LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP-ASGVIRT 641 + I E AL GT GA D DVG N +Y L + +P S + Sbjct: 140 DKHVSLEISESALTGTQFPLQGADDMDVGQNALQNYVLSQNENFILKQHANPDGSKYVEM 199 Query: 642 --NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699 K LDRE LK +A+DGGTP +S TV + I + D ND+ PVF I EN Sbjct: 200 VLQKPLDRERHPHLSLKLIAVDGGTPQRSGTVNIDITVLDANDNVPVFNQSVYKASIMEN 259 Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSI---KGGDDSNSFSLETRQGSDKAELVTMVDLDY 756 + IGT + + A D D G ++ YS+ KGG + F+++ G+ + +DY Sbjct: 260 TKIGTNVVTVNATDADSGIYGLITYSLSKMKGG-AAEIFTIDESTGA----ITVSGPIDY 314 Query: 757 ESPRKKYELVIRAAS-PPLWNDVRVEILVTDVNDNAPVM 794 E R KYE+ + A L +V V+DVNDN PV+ Sbjct: 315 EKDR-KYEVRVEARDRGGLTGTSKVVFDVSDVNDNPPVI 352 >UniRef50_Q24298 Cluster: DE-cadherin precursor; n=5; Neoptera|Rep: DE-cadherin precursor - Drosophila melanogaster (Fruit fly) Length = 1507 Score = 216 bits (527), Expect = 8e-54 Identities = 302/1140 (26%), Positives = 476/1140 (41%), Gaps = 105/1140 (9%) Query: 61 TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYT---VLV 117 T+E V D P+ + F I+ +G + T + DR++ V V Sbjct: 109 TVEAVDPD---PDQVIRYSIVQSPFERPKFFINPSTGVIFTTHTFDRDEPIHEKFVFVTV 165 Query: 118 KATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKAT 177 +ATD P D T +V I D NDN P F++ Y S+ E+ + V+ I A+ Sbjct: 166 QATDNGLPPLD---DVCTFNVTIEDINDNAPAFNKARYDESMSENAQ--PDAVVMTISAS 220 Query: 178 DADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237 D D G NS + Y I+ F ID SG + L + +D +SY +++RA + P Sbjct: 221 DFDDGNNSLVEYEILRERDFQYFKIDKESGIIYLKRPIDKRPGQSYAIIVRAYNV-VPDP 279 Query: 238 SNTTQLLINIRDVNDNA--PRFY----TSLFQESVSENVPIGYSIVRVQAYDADEG-VNA 290 Q+ + IR V + P F T ++ + +N + +R + D+ V Sbjct: 280 PQDAQIEVRIRVVESSIKPPSFVNPIDTPIYLKENLKNFTHPIATLRAVSNMPDKPEVIF 339 Query: 291 ELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350 EL T++ + N + I + LD E Y L + + + T Sbjct: 340 ELNTGRTEQTNSKNTFVFNQIG-NEVTISLGKTLDYEAITDYTLTMIVRNTHE---LGTE 395 Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGN 407 + + E+EPPGTPV+ + A D D +N + +E+ + Sbjct: 396 HQIKIQVEDVNDNIPYYTEVKSGTILENEPPGTPVMQVRAFDMDGTSANNIVSFELA--D 453 Query: 408 TRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTA-------MVQIN 458 R F+I G IT D ++ Y + V A+D+ S D + +I+ Sbjct: 454 NREYFTIDPNTGN--ITALTTFDREERDFYNVKVIASDNSPSSLFDNGEPNRGHQVFRIS 511 Query: 459 ITDANNYAPVFENAPYTAS-VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517 I D N++ P F+ Y A + EDA T V+ V A D D +QI YS+ S +A Sbjct: 512 IGDKNDHKPHFQQDKYLAERLLEDANTNTEVIEVKAEDEDNA--SQILYSIESGNVGDA- 568 Query: 518 AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577 F I +TG IT N+ LD ET++ Y L V A DG D T V I + DVNDN Sbjct: 569 ------FKIGLKTGKITVNQKLDYETITEYELKVRAFDG---IYDDYTTVVIKIEDVNDN 619 Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDADV-GLNGRIHYELDPKDREEGSFVIDPAS 636 PVFKQ Y+ I+E+ + V A D D+ N H + + ID S Sbjct: 620 PPVFKQD-YSVTILEETTYDDCILTVEAYDPDIKDRNADQHIVYSIHQNDGNRWTIDN-S 677 Query: 637 GVIRTNKALDRESVATHD-----LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691 G +R K LDR+ H +KA DG S+ V + ++DIND+ P ++ Sbjct: 678 GCLRLVKTLDRDPPNGHKNWQVLIKANDEDGVGTTVSTVKEVTVTLKDINDNAPFLINE- 736 Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751 + Y EN G + +++A+D D+ P A +++ G D + ++T+ D L Sbjct: 737 MPVYWQENRNPGHVV-QLQANDYDDTPGAG-NFTF-GIDSEATPDIKTKFSMDGDYLHAN 793 Query: 752 VDLDYESPRKKYELVIRAASPPLWNDVRVEIL---VTDVNDNAPVMKDFQIIFNNYKDCF 808 V D E+ +K+Y + IR + + V IL + DVNDNA +I NYK Sbjct: 794 VQFDREA-QKEYFIPIRISDSGVPRQSAVSILHLVIGDVNDNAMSEGSSRIFIYNYKGEA 852 Query: 809 PVGPFGRVPAYDADVTD-KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLA--TM 865 P GRV D D D + +Y + LN +TG +T+ L+ Sbjct: 853 PETDIGRVFVDDLDDWDLEDKYFEWKDLPHDQFRLNPSTGMITMLVHTAEGEYDLSFVVT 912 Query: 866 EVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIP 925 E S+ + + A + + VR + EE + S ++R ++T E+F+S F ++ Sbjct: 913 EDSMFVPRHSVDAYVTVVVRELPEEAVDKSGSIRFINVTKEEFISVPRDFQSPDALSL-- 970 Query: 926 CPKENIYI-FSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRT 984 K+ + + + +T V+ + +V + SP+Y+P L V ++ Sbjct: 971 --KDRLQLSLAKLFNTSVSNVDVFTVLQNENHTLDVRFSAHGSPYYAPEKLNGIVAQNQQ 1028 Query: 985 TLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTC 1044 L +Q+L +N +ECL + KF N P Y + S T Sbjct: 1029 RLENELDLQML-----------MVNIDECL-IEKFKCEESCTNELHKSSVP-YMIYSNT- 1074 Query: 1045 QCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCE 1104 F GVN + + CE GS + +C C ID +T CE Sbjct: 1075 ---TSFVGVNA-FVQAQCVCEAPLMRRCLNGGSPRYGEND---VCD-C-ID-GFTGPHCE 1124 Query: 1105 LRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNER-----HDFLALEL 1159 L + +F S + + + + + L+ Q GL++Y G N DFLALEL Sbjct: 1125 LVSVAFYGSGYAFYEPIAACNNTKISLEITPQIDQGLIMYLGPLNFNPLLAISDFLALEL 1184 Score = 200 bits (489), Expect = 3e-49 Identities = 182/658 (27%), Positives = 304/658 (46%), Gaps = 57/658 (8%) Query: 167 DNPVIAKIKATDADVGANSAIRYAIIGGNTQM-QFSIDSLSGDVSLVKTLDYEQVRSYRL 225 +N + ++A D D + IRY+I+ + +F I+ +G + T D ++ + Sbjct: 103 ENTYVLTVEAVDPD--PDQVIRYSIVQSPFERPKFFINPSTGVIFTTHTFDRDEPIHEKF 160 Query: 226 V---IRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY 282 V ++A D G P + + I D+NDNAP F + + ES+SEN ++ + A Sbjct: 161 VFVTVQATDNGLPPLDDVCTFNVTIEDINDNAPAFNKARYDESMSENAQPDAVVMTISAS 220 Query: 283 DADEGVNAELTY-TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD- 340 D D+G N+ + Y + ++D+ ID SG +Y +D+ Y ++V A + Sbjct: 221 DFDDGNNSLVEYEILRERDFQ-----YFKIDKESGIIYLKRPIDKRPGQSYAIIVRAYNV 275 Query: 341 GGDPPRSATATXXXXXXXXXXXXXXFM-PGQYEVELAEDEPPGT-PVVTLTATDADEDN- 397 DPP+ A F+ P + L E+ T P+ TL A D Sbjct: 276 VPDPPQDAQIEVRIRVVESSIKPPSFVNPIDTPIYLKENLKNFTHPIATLRAVSNMPDKP 335 Query: 398 RLHYEITGG-----NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT 452 + +E+ G N++ F I++ + LD++ Y LT+ ++ Sbjct: 336 EVIFELNTGRTEQTNSKNTFVFNQIGNEVTISLGKTLDYEAITDYTLTMIVRNTHELGTE 395 Query: 453 AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512 ++I + D N+ P + + ++ E+ P GT V+ V A D D G +A + I Sbjct: 396 HQIKIQVEDVNDNIPYYTEVK-SGTILENEPPGTPVMQVRAFDMD-GTSA-------NNI 446 Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD------ 566 + +A + + F I+P TG IT DRE Y + V A D SL D + Sbjct: 447 VSFELADNREYFTIDPNTGNITALTTFDREERDFYNVKVIASDNSPSSLFDNGEPNRGHQ 506 Query: 567 -VEISVVDVNDNEPVFKQQLYTA-NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624 IS+ D ND++P F+Q Y A ++EDA T V +V A D D +I Y ++ + Sbjct: 507 VFRISIGDKNDHKPHFQQDKYLAERLLEDANTNTEVIEVKAEDEDNA--SQILYSIESGN 564 Query: 625 REEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP 684 + +F I +G I N+ LD E++ ++LK A DG ++ V IKIED+ND+P Sbjct: 565 VGD-AFKIGLKTGKITVNQKLDYETITEYELKVRAFDGIYDDYTTVV---IKIEDVNDNP 620 Query: 685 PVFESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAVVH--YSIKGGDDSNSFSLETRQ 741 PVF+ D + I E + I + A+DPD + NA H YSI +D N ++++ Sbjct: 621 PVFKQD-YSVTILEETTYDDCILTVEAYDPDIKDRNADQHIVYSIH-QNDGNRWTID--- 675 Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRA-----ASPPLWNDVRVEILVTDVNDNAPVM 794 S LV +D D + K ++++I+A + V + + D+NDNAP + Sbjct: 676 NSGCLRLVKTLDRDPPNGHKNWQVLIKANDEDGVGTTVSTVKEVTVTLKDINDNAPFL 733 Score = 189 bits (461), Expect = 8e-46 Identities = 189/735 (25%), Positives = 318/735 (43%), Gaps = 79/735 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND++P F +Y+ S+ E A V+T+ A+D D G N+ VEY I L Sbjct: 183 VTIEDINDNAPAFNKARYDESMSENAQPDAVVMTISASDFDDGNNSLVEYEI-------L 235 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQA-SPVSDR 129 D F+ID SG + + +D+ Y ++V+A + P D Sbjct: 236 RERDF------------QYFKIDKESGIIYLKRPIDKRPGQSYAIIVRAYNVVPDPPQD- 282 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYT-VSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 + + + +++ + P F T + + E++ +P IA ++A +++ + Sbjct: 283 --AQIEVRIRVVESSIKPPSFVNPIDTPIYLKENLKNFTHP-IATLRAV-SNMPDKPEVI 338 Query: 189 YAIIGGNTQMQ-----FSIDSLSGDV--SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 + + G T+ F + + +V SL KTLDYE + Y L + ++ + Sbjct: 339 FELNTGRTEQTNSKNTFVFNQIGNEVTISLGKTLDYEAITDYTLTMIVRN--THELGTEH 396 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTD-K 299 Q+ I + DVNDN P +YT + ++ EN P G +++V+A+D D N +++ + D + Sbjct: 397 QIKIQVEDVNDNIP-YYTEVKSGTILENEPPGTPVMQVRAFDMDGTSANNIVSFELADNR 455 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG--------GDPPRSATAT 351 +Y TIDP +G + DRE + Y + V A+D G+P R Sbjct: 456 EY-------FTIDPNTGNITALTTFDREERDFYNVKVIASDNSPSSLFDNGEPNRGHQV- 507 Query: 352 XXXXXXXXXXXXXXFMPGQYEVE-LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG 410 F +Y E L ED T V+ + A D D +++ Y I GN Sbjct: 508 FRISIGDKNDHKPHFQQDKYLAERLLEDANTNTEVIEVKAEDEDNASQILYSIESGNVGD 567 Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFE 470 F I + G+ ITV Q LD++ Y L V A D G D V I I D N+ PVF+ Sbjct: 568 AFKIGLKTGK--ITVNQKLDYETITEYELKVRAFD-GIYDDYTTVVIKIEDVNDNPPVFK 624 Query: 471 NAPYTASVFEDAPIGTTVLVVSATDSDV---GINAQITYSLSSEISNEAVAHHDQQFVIN 527 Y+ ++ E+ +L V A D D+ + I YS+ N ++ I+ Sbjct: 625 Q-DYSVTILEETTYDDCILTVEAYDPDIKDRNADQHIVYSIHQNDGN--------RWTID 675 Query: 528 PQTGAITTNKLLDRETMSGY-----LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK 582 +G + K LDR+ +G+ L+ DG ++S +V +++ D+NDN P Sbjct: 676 -NSGCLRLVKTLDRDPPNGHKNWQVLIKANDEDGVGTTVSTVKEVTVTLKDINDNAPFLI 734 Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLN-GRIHYELDPKDREEGSFVIDPASGVIRT 641 ++ E+ G V Q+ A D D G + +D + + + Sbjct: 735 NEM-PVYWQENRNPG-HVVQLQANDYDDTPGAGNFTFGIDSEATPDIKTKFSMDGDYLHA 792 Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701 N DRE+ + + D G P QS+ I+H+ I D+ND+ S + Y + Sbjct: 793 NVQFDREAQKEYFIPIRISDSGVPRQSAVSILHLVIGDVNDNAMSEGSSRIFIYNYKGEA 852 Query: 702 IGTTIGEIRAHDPDE 716 T IG + D D+ Sbjct: 853 PETDIGRVFVDDLDD 867 Score = 121 bits (291), Expect = 3e-25 Identities = 112/401 (27%), Positives = 179/401 (44%), Gaps = 26/401 (6%) Query: 463 NNYAPVFEN-APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521 +N P F+N A Y V E+ P T VL V A D D + I YS+ Sbjct: 81 DNRKPAFKNCAGYAPKVKEEQPENTYVLTVEAVDPDP--DQVIRYSIVQS------PFER 132 Query: 522 QQFVINPQTGAITTNKLLDRETM---SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578 +F INP TG I T DR+ +TV A D G+P L D +++ D+NDN Sbjct: 133 PKFFINPSTGVIFTTHTFDRDEPIHEKFVFVTVQATDNGLPPLDDVCTFNVTIEDINDNA 192 Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638 P F + Y ++ E+A V + A+D D G N + YE+ ++R+ F ID SG+ Sbjct: 193 PAFNKARYDESMSENAQPDAVVMTISASDFDDGNNSLVEYEI-LRERDFQYFKIDKESGI 251 Query: 639 IRTNKALDRESVATHDLKAVAID-GGTPPQSSTVIVHIKIEDINDSPPVFESDCLT-FYI 696 I + +D+ ++ + A + PPQ + + V I++ + + PP F + T Y+ Sbjct: 252 IYLKRPIDKRPGQSYAIIVRAYNVVPDPPQDAQIEVRIRVVESSIKPPSFVNPIDTPIYL 311 Query: 697 SENSPIGT-TIGEIRA--HDPDEGPNAVVHYSIKGGDDSNS-FSLETRQGSDKAELVTMV 752 EN T I +RA + PD+ P + + + +NS + Q ++ + Sbjct: 312 KENLKNFTHPIATLRAVSNMPDK-PEVIFELNTGRTEQTNSKNTFVFNQIGNEVTISLGK 370 Query: 753 DLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQ--IIFNNYKDCFPV 810 LDYE+ +I + L + +++I V DVNDN P + + I N P Sbjct: 371 TLDYEAITDYTLTMIVRNTHELGTEHQIKIQVEDVNDNIPYYTEVKSGTILENEP---PG 427 Query: 811 GPFGRVPAYDADVTDKLQYRILS-GNNANLILLNETTGSMT 850 P +V A+D D T +N ++ TG++T Sbjct: 428 TPVMQVRAFDMDGTSANNIVSFELADNREYFTIDPNTGNIT 468 Score = 114 bits (274), Expect = 4e-23 Identities = 130/527 (24%), Positives = 226/527 (42%), Gaps = 41/527 (7%) Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGN-TRGRFSITSQNGRGLITVAQPL 429 Y ++ E++P T V+T+ A D D D + Y I R +F I G T Sbjct: 93 YAPKVKEEQPENTYVLTVEAVDPDPDQVIRYSIVQSPFERPKFFINPSTGVIFTTHTFDR 152 Query: 430 DFKQERRYV-LTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 D ++V +TV ATD+G D + I D N+ AP F A Y S+ E+A Sbjct: 153 DEPIHEKFVFVTVQATDNGLPPLDDVCTFNVTIEDINDNAPAFNKARYDESMSENAQPDA 212 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 V+ +SA+D D G N+ + Y + E Q F I+ ++G I + +D+ Sbjct: 213 VVMTISASDFDDGNNSLVEYEILRE-------RDFQYFKIDKESGIIYLKRPIDKRPGQS 265 Query: 547 YLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS--VSQV 603 Y + V A + P +V I VV+ + P F + T +++ L + ++ + Sbjct: 266 YAIIVRAYNVVPDPPQDAQIEVRIRVVESSIKPPSFVNPIDTPIYLKENLKNFTHPIATL 325 Query: 604 GATDADVGLNGRIHYELDPKDREE----GSFVIDPASG--VIRTNKALDRESVATHDLKA 657 A +++ + +EL+ E+ +FV + I K LD E++ + L Sbjct: 326 RAV-SNMPDKPEVIFELNTGRTEQTNSKNTFVFNQIGNEVTISLGKTLDYEAITDYTLTM 384 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 + T + + I++ED+ND+ P + ++ + I EN P GT + ++RA D D G Sbjct: 385 IV--RNTHELGTEHQIKIQVEDVNDNIPYY-TEVKSGTILENEPPGTPVMQVRAFDMD-G 440 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA--SP--- 772 +A S + D+ F+++ G+ + + D E R Y + + A+ SP Sbjct: 441 TSANNIVSFELADNREYFTIDPNTGN----ITALTTFDREE-RDFYNVKVIASDNSPSSL 495 Query: 773 -----PLWNDVRVEILVTDVNDNAP-VMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK 826 P I + D ND+ P +D + +D V A D D + Sbjct: 496 FDNGEPNRGHQVFRISIGDKNDHKPHFQQDKYLAERLLEDANTNTEVIEVKAEDEDNASQ 555 Query: 827 LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGV 873 + Y I SGN + + TG +T++ +L+ ++V DG+ Sbjct: 556 ILYSIESGNVGDAFKIGLKTGKITVNQKLDYETITEYELKVRAFDGI 602 >UniRef50_UPI000065EB3B Cluster: Homolog of Brachydanio rerio "Paraxial protocadherin.; n=1; Takifugu rubripes|Rep: Homolog of Brachydanio rerio "Paraxial protocadherin. - Takifugu rubripes Length = 980 Score = 215 bits (526), Expect = 1e-53 Identities = 172/631 (27%), Positives = 289/631 (45%), Gaps = 40/631 (6%) Query: 91 RIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQF 150 R+ G L +DRE++ R+T T S + V I D NDN P+F Sbjct: 53 RVRESDGELTVGERIDRERICRHTPQCLITFDVVNFSKDRYKLIHVAVEIRDINDNSPEF 112 Query: 151 SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS---- 206 K V + E+ +V + A DADVG+N Y I + F+ID L Sbjct: 113 PNKESIVEISENAAVGSR--VPLDPAADADVGSNYIQSYQI---SVNSHFTIDVLLRADG 167 Query: 207 ---GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263 ++ L+K LD E SY + + A DGG P RS +T++ I + D NDN+P F + F Sbjct: 168 VKYAELVLMKELDRETQSSYTVDLVATDGGHPFRSGSTKITILVTDFNDNSPVFDQNSFS 227 Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323 ++ E+ P+G I+ + A DAD+G+N E+ Y K + + +D +SG + Sbjct: 228 VTLPEDAPVGTVILNLNAVDADDGLNGEVVYGF-GKQVSHEIRQLFQVDHKSGRLTLRSP 286 Query: 324 LDRETQAKYQLLVTATD-GGDPPRS-------ATATXXXXXXXXXXXXXXFMPGQYEVEL 375 +D E + Y+L V ATD G +P S T G + Sbjct: 287 VDFEEKTTYELDVQATDLGANPSPSLCKIIIHITDVNDNAPEISITPMTSMTTGIAYISE 346 Query: 376 AEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSI-TSQNGRGLITVAQPLDFKQE 434 A D+ +++ D+ ++++H + G F + + +I A LD ++ Sbjct: 347 AADKDSLVALISTQDRDSGVNSQVHCSLYG---HDHFKLRQAYEDSYMIVTAASLDRERI 403 Query: 435 RRYVLTVSATDSGGRSDTAMVQ--INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492 Y LTV A D G ++Q I ++D N+ AP F SV E+ P G + V Sbjct: 404 SEYNLTVMAEDFGSPPMRKIIQYTIRLSDENDNAPHFARGVTEVSVVENNPPGAYITTVE 463 Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETMSGYLLTV 551 A+D+D+ N +ITY L + + + FV +N +G++ + + E M + V Sbjct: 464 ASDADLANNGKITYRL---VDSVIMGSPVNTFVSLNSVSGSLYALRSFNYEVMKQLDVHV 520 Query: 552 TARDGGVPSLSDTTDVEISVVDVNDNEP-VFKQQLYTAN----IMEDALVGTSVSQVGAT 606 A DGG P L T + + ++D NDN+P + + LY + + +D+ G ++Q+ AT Sbjct: 521 QASDGGSPQLQTTAVIRLKILDQNDNQPLIVEPPLYKGSAEVFLPKDSPGGYVLTQIKAT 580 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 DAD G+N ++ Y++ + F I+ +G + ++ L + T + D G+P Sbjct: 581 DADEGINAQLSYKI--IEGGHLGFSINKDTGKVHVSRQLTYDLSDTVKVTVAVSDNGSPS 638 Query: 667 QSSTVIVHIKIED--INDSPPVFESDCLTFY 695 +ST I+H+ + + P + ++D F+ Sbjct: 639 LTSTAIIHVSFTEGTLPSVPSLAQNDSEVFF 669 Score = 213 bits (520), Expect = 6e-53 Identities = 169/579 (29%), Positives = 268/579 (46%), Gaps = 42/579 (7%) Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293 S R + + IRD+NDN+P F +SEN +G + A DAD G N + Sbjct: 89 SKDRYKLIHVAVEIRDINDNSPEFPNKESIVEISENAAVGSRVPLDPAADADVGSNYIQS 148 Query: 294 YTMTDKDYTGNVDLPITIDP-RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352 Y ++ + +D+ + D + + +LDRETQ+ Y + + ATDGG P RS + Sbjct: 149 YQISVNSHF-TIDVLLRADGVKYAELVLMKELDRETQSSYTVDLVATDGGHPFRSGSTKI 207 Query: 353 XXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG------ 406 F + V L ED P GT ++ L A DAD+ L+ E+ G Sbjct: 208 TILVTDFNDNSPVFDQNSFSVTLPEDAPVGTVILNLNAVDADDG--LNGEVVYGFGKQVS 265 Query: 407 -NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQI--NITDAN 463 R F + ++GR +T+ P+DF+++ Y L V ATD G ++ +I +ITD N Sbjct: 266 HEIRQLFQVDHKSGR--LTLRSPVDFEEKTTYELDVQATDLGANPSPSLCKIIIHITDVN 323 Query: 464 NYAPVFENAPYT------ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517 + AP P T A + E A + V ++S D D G+N+Q+ SL + Sbjct: 324 DNAPEISITPMTSMTTGIAYISEAADKDSLVALISTQDRDSGVNSQVHCSLYGHDHFKLR 383 Query: 518 AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577 ++ ++I T LDRE +S Y LTV A D G P + I + D NDN Sbjct: 384 QAYEDSYMI-------VTAASLDRERISEYNLTVMAEDFGSPPMRKIIQYTIRLSDENDN 436 Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK---DREEGSFV-ID 633 P F + + +++E+ G ++ V A+DAD+ NG+I Y L +FV ++ Sbjct: 437 APHFARGVTEVSVVENNPPGAYITTVEASDADLANNGKITYRLVDSVIMGSPVNTFVSLN 496 Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS------PPVF 687 SG + ++ + E + D+ A DGG+P +T ++ +KI D ND+ PP++ Sbjct: 497 SVSGSLYALRSFNYEVMKQLDVHVQASDGGSPQLQTTAVIRLKILDQNDNQPLIVEPPLY 556 Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747 + F + ++SP G + +I+A D DEG NA + Y I G FS+ G K Sbjct: 557 KGSAEVF-LPKDSPGGYVLTQIKATDADEGINAQLSYKIIEGGHL-GFSINKDTG--KVH 612 Query: 748 LVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTD 786 + + D K V SP L + + + T+ Sbjct: 613 VSRQLTYDLSDTVKVTVAVSDNGSPSLTSTAIIHVSFTE 651 Score = 198 bits (483), Expect = 2e-48 Identities = 160/589 (27%), Positives = 267/589 (45%), Gaps = 55/589 (9%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 IH + + D ND+SP F ++ + E A+ G+ V A D D+G N Y I + + Sbjct: 96 IHVAVEIRDINDNSPEFPNKESIVEISENAAVGSRVPLDPAADADVGSNYIQSYQISVNS 155 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASP 125 T++ + R DG + L+ LDRE + YTV + ATD P Sbjct: 156 HFTIDV----------------LLRADGVKYAELVLMKELDRETQSSYTVDLVATDGGHP 199 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 S + I + + D NDN P F + +++V++ ED V VI + A DAD G N Sbjct: 200 FR---SGSTKITILVTDFNDNSPVFDQNSFSVTLPEDAPV--GTVILNLNAVDADDGLNG 254 Query: 186 AIRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 + Y + + F +D SG ++L +D+E+ +Y L ++A D G+ + + Sbjct: 255 EVVYGFGKQVSHEIRQLFQVDHKSGRLTLRSPVDFEEKTTYELDVQATDLGANPSPSLCK 314 Query: 243 LLINIRDVNDNAPRF----YTSLFQ--ESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 ++I+I DVNDNAP TS+ +SE + + D D GVN+++ ++ Sbjct: 315 IIIHITDVNDNAPEISITPMTSMTTGIAYISEAADKDSLVALISTQDRDSGVNSQVHCSL 374 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 D+ L + S + T+ LDRE ++Y L V A D G PP Sbjct: 375 YGHDH---FKLRQAYED-SYMIVTAASLDRERISEYNLTVMAEDFGSPPMRKIIQYTIRL 430 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRG---R 411 F G EV + E+ PPG + T+ A+DAD + ++ Y + G Sbjct: 431 SDENDNAPHFARGVTEVSVVENNPPGAYITTVEASDADLANNGKITYRLVDSVIMGSPVN 490 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVF 469 ++ + G + + +++ ++ + V A+D G TA++++ I D N+ P+ Sbjct: 491 TFVSLNSVSGSLYALRSFNYEVMKQLDVHVQASDGGSPQLQTTAVIRLKILDQNDNQPLI 550 Query: 470 ENAPY---TASVF--EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524 P +A VF +D+P G + + ATD+D GINAQ++Y + + F Sbjct: 551 VEPPLYKGSAEVFLPKDSPGGYVLTQIKATDADEGINAQLSYKI--------IEGGHLGF 602 Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 IN TG + ++ L + +TV D G PSL+ T + +S + Sbjct: 603 SINKDTGKVHVSRQLTYDLSDTVKVTVAVSDNGSPSLTSTAIIHVSFTE 651 Score = 177 bits (430), Expect = 5e-42 Identities = 160/529 (30%), Positives = 240/529 (45%), Gaps = 51/529 (9%) Query: 377 EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS---ITSQNGRGLITVAQPLDFKQ 433 E+ PGT + TL D L T +F+ I + G +TV + +D ++ Sbjct: 15 EEGAPGTVIGTLAK---DMSLSLSSSKTNFRMMKQFNDSFIRVRESDGELTVGERIDRER 71 Query: 434 ERRY----VLTVSATD-SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 R+ ++T + S R V + I D N+ +P F N + E+A +G+ V Sbjct: 72 ICRHTPQCLITFDVVNFSKDRYKLIHVAVEIRDINDNSPEFPNKESIVEISENAAVGSRV 131 Query: 489 LVVSATDSDVGINAQITYSLS--SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 + A D+DVG N +Y +S S + + + D + + K LDRET S Sbjct: 132 PLDPAADADVGSNYIQSYQISVNSHFTIDVLLRAD-----GVKYAELVLMKELDRETQSS 186 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y + + A DGG P S +T + I V D NDN PVF Q ++ + EDA VGT + + A Sbjct: 187 YTVDLVATDGGHPFRSGSTKITILVTDFNDNSPVFDQNSFSVTLPEDAPVGTVILNLNAV 246 Query: 607 DADVGLNGRIHYELDPKDREE--GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 DAD GLNG + Y + E F +D SG + +D E T++L A D G Sbjct: 247 DADDGLNGEVVYGFGKQVSHEIRQLFQVDHKSGRLTLRSPVDFEEKTTYELDVQATDLGA 306 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLT------FYISENSPIGTTIGEIRAHDPDEGP 718 P S + I I D+ND+ P +T YISE + + + I D D G Sbjct: 307 NPSPSLCKIIIHITDVNDNAPEISITPMTSMTTGIAYISEAADKDSLVALISTQDRDSGV 366 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLW 775 N+ VH S+ G D F L + D +VT LD E +Y L + A SPP+ Sbjct: 367 NSQVHCSLYGHD---HFKLR-QAYEDSYMIVTAASLDRER-ISEYNLTVMAEDFGSPPMR 421 Query: 776 NDVRVEILVTDVNDNAP----VMKDFQIIFNNYKDCFPVGPF-GRVPAYDADVTD--KLQ 828 ++ I ++D NDNAP + + ++ NN P G + V A DAD+ + K+ Sbjct: 422 KIIQYTIRLSDENDNAPHFARGVTEVSVVENN-----PPGAYITTVEASDADLANNGKIT 476 Query: 829 YR----ILSGNNAN-LILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 YR ++ G+ N + LN +GS+ N V K + V +DG Sbjct: 477 YRLVDSVIMGSPVNTFVSLNSVSGSLYALRSFNYEVMKQLDVHVQASDG 525 Score = 176 bits (429), Expect = 6e-42 Identities = 145/500 (29%), Positives = 227/500 (45%), Gaps = 43/500 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+SPVF+ + ++ E A GT +L L A D D G N EV Y Sbjct: 209 ILVTDFNDNSPVFDQNSFSVTLPEDAPVGTVILNLNAVDADDGLNGEVVYGF-------- 260 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 ++ +F++D +SG L R+ +D E+ Y + V+ATD + S Sbjct: 261 --------GKQVSHEIRQLFQVDHKSGRLTLRSPVDFEEKTTYELDVQATDLGANPS--- 309 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTD----NPVIAKIKATDADVGANSA 186 S I ++I D NDN P+ S T +++ + ++A I D D G NS Sbjct: 310 PSLCKIIIHITDVNDNAPEISITPMTSMTTGIAYISEAADKDSLVALISTQDRDSGVNSQ 369 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 + ++ G + F + D ++ T LD E++ Y L + A+D GSP Q Sbjct: 370 VHCSLYGHD---HFKLRQAYEDSYMIVTAASLDRERISEYNLTVMAEDFGSPPMRKIIQY 426 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 I + D NDNAP F + + SV EN P G I V+A DAD N ++TY + D G Sbjct: 427 TIRLSDENDNAPHFARGVTEVSVVENNPPGAYITTVEASDADLANNGKITYRLVDSVIMG 486 Query: 304 N-VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 + V+ ++++ SG +Y + E + + V A+DGG P TA Sbjct: 487 SPVNTFVSLNSVSGSLYALRSFNYEVMKQLDVHVQASDGGSPQLQTTAVIRLKILDQNDN 546 Query: 363 XXXFM-----PGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSIT 415 + G EV L +D P G + + ATDADE + +L Y+I G G FSI Sbjct: 547 QPLIVEPPLYKGSAEVFLPKDSPGGYVLTQIKATDADEGINAQLSYKIIEGGHLG-FSIN 605 Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAP 473 G+ + V++ L + +TV+ +D+G S TA++ ++ T+ V A Sbjct: 606 KDTGK--VHVSRQLTYDLSDTVKVTVAVSDNGSPSLTSTAIIHVSFTE-GTLPSVPSLAQ 662 Query: 474 YTASVFEDAPIGTTVLVVSA 493 + VF + +++V A Sbjct: 663 NDSEVFFEWDTSIAIIIVLA 682 Score = 172 bits (418), Expect = 1e-40 Identities = 145/526 (27%), Positives = 252/526 (47%), Gaps = 38/526 (7%) Query: 373 VELAEDEPPGTPVVTLTATDADEDNRL--HYEITGGNTRGRFSITSQNG--RGLITVAQP 428 VE++E+ G+ V A DAD + Y+I+ + + +G + + + Sbjct: 119 VEISENAAVGSRVPLDPAADADVGSNYIQSYQISVNSHFTIDVLLRADGVKYAELVLMKE 178 Query: 429 LDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD + + Y + + ATD G RS + + I +TD N+ +PVF+ ++ ++ EDAP+GT Sbjct: 179 LDRETQSSYTVDLVATDGGHPFRSGSTKITILVTDFNDNSPVFDQNSFSVTLPEDAPVGT 238 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 +L ++A D+D G+N ++ Y ++S+E Q F ++ ++G +T +D E + Sbjct: 239 VILNLNAVDADDGLNGEVVYGFGKQVSHEI----RQLFQVDHKSGRLTLRSPVDFEEKTT 294 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT------ANIMEDALVGTSV 600 Y L V A D G + I + DVNDN P T A I E A + V Sbjct: 295 YELDVQATDLGANPSPSLCKIIIHITDVNDNAPEISITPMTSMTTGIAYISEAADKDSLV 354 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 + + D D G+N ++H L D + + S +I T +LDRE ++ ++L +A Sbjct: 355 ALISTQDRDSGVNSQVHCSLYGHDHFKLRQAYED-SYMIVTAASLDRERISEYNLTVMAE 413 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 D G+PP + I++ D ND+ P F + EN+P G I + A D D N Sbjct: 414 DFGSPPMRKIIQYTIRLSDENDNAPHFARGVTEVSVVENNPPGAYITTVEASDADLANNG 473 Query: 721 VVHY----SIKGGDDSNSF-SLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SP 772 + Y S+ G N+F SL + GS L + +YE K+ ++ ++A+ SP Sbjct: 474 KITYRLVDSVIMGSPVNTFVSLNSVSGS----LYALRSFNYEV-MKQLDVHVQASDGGSP 528 Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFG----RVPAYDAD--VTD 825 L + + + D NDN P++ + + + + P P G ++ A DAD + Sbjct: 529 QLQTTAVIRLKILDQNDNQPLIVEPPLYKGSAEVFLPKDSPGGYVLTQIKATDADEGINA 588 Query: 826 KLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 +L Y+I+ G + +N+ TG + +S QL ++ + V+V+D Sbjct: 589 QLSYKIIEGGHLG-FSINKDTGKVHVSRQLTYDLSDTVKVTVAVSD 633 >UniRef50_Q95YK1 Cluster: Protocadherin; n=1; Ciona savignyi|Rep: Protocadherin - Ciona savignyi (Pacific transparent sea squirt) Length = 1177 Score = 215 bits (524), Expect = 2e-53 Identities = 188/636 (29%), Positives = 281/636 (44%), Gaps = 50/636 (7%) Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 D + SG + R +DRE QA + R+ S + + I D NDN Sbjct: 84 DAVDLGTSSGLITLRRRVDRETECGQAKECIIKVQAVMLPQRVFSLLNLEIVITDTNDNA 143 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNT--QMQFSIDSL 205 P F K V+V E ++V D + +A D D G NSAI Y I Q+ ++ Sbjct: 144 PTFPHKPIIVNVSESVTVNDIINLDSFQARDLDSGNNSAITYTIAPSQPFGVNQYIDEAG 203 Query: 206 SGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263 + L+ T LDYE + + L + A D G+P SN L I + D ND++P F S F Sbjct: 204 RPHLQLIVTSELDYETKQVHHLTLYATDNGTPPLSNNVALRILVTDANDHSPVFAQSEFV 263 Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323 + + EN P G+ I RV A D D G N + Y + D+ + L +T+D +G V Sbjct: 264 KELKENQPPGF-ITRVHAVDRDSGNNGRVQYFLGDESEAVSHQL-VTVDKDTGDVTLVQN 321 Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE-------LA 376 LDRET ++L+ A D + ++ + + V+ ++ Sbjct: 322 LDRETHDGMRILIEARDSAPTNQRSSRMWLVLRIDDDNDNAPTINMNFIVDADGQTAYIS 381 Query: 377 EDEPPGTPVVTLTATDADEDNRLHYEIT----------GGNTRGRFSITSQNGRGLITVA 426 E P GT V ++A+DAD +I+ NT G F + + GLI Sbjct: 382 EASPIGTYVAYVSASDADHGKNSEVDISIRTLVFGEPEYANT-GHFVLAAD---GLIGTG 437 Query: 427 QPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 LD + + Y + V A D+G RS + + I D N+ APVF+ Y ++ E + Sbjct: 438 LELDREIQNSYKVVVEARDAGDVPRSSFNNITVIILDENDNAPVFQKPVYPVTLSEADGV 497 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEI---SNEAVAH----HDQQFVINPQTGAITTNK 537 GTTV VSATD D T + EI N V + D F IN +TG IT + Sbjct: 498 GTTVTTVSATDKDALFPPVWTKNKKKEIVPSMNGKVTYLIDSDDNTFSINAETGEITLVR 557 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF-KQQLYTANIMEDALV 596 LDRE S + +T+ ARDGG P T +++ V DVNDN P+F + + L Sbjct: 558 PLDREGQSDWEVTIIARDGGSPYKESTCILKVVVSDVNDNRPLFINPAIDNSTAYATILR 617 Query: 597 GTSVSQVGATDADVGLNGRIHYEL----DPKDREE-------GSFVIDPASGVIRTNKAL 645 ++++ A D D + ++ L K +E FV+D A+G +R N + Sbjct: 618 DDVITRIQAVDYDSPMFSKVEISLLSVDGLKSTQETDGVEPYSFFVLDRATGDLRLNMST 677 Query: 646 D--RESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679 + V +H + A D G PP S + I + D Sbjct: 678 ADLNDIVGSHVIVVKATDNGQPPLESRTSITIIVSD 713 Score = 194 bits (472), Expect = 4e-47 Identities = 176/620 (28%), Positives = 282/620 (45%), Gaps = 50/620 (8%) Query: 206 SGDVSLVKTLDYEQV--RSYRLVIRAQDGGSPSRS-NTTQLLINIRDVNDNAPRFYTSLF 262 SG ++L + +D E ++ +I+ Q P R + L I I D NDNAP F Sbjct: 92 SGLITLRRRVDRETECGQAKECIIKVQAVMLPQRVFSLLNLEIVITDTNDNAPTFPHKPI 151 Query: 263 QESVSENVPIG--YSIVRVQAYDADEGVNAELTYTMTDKDYTG-NVDLPITIDPRSGWVY 319 +VSE+V + ++ QA D D G N+ +TYT+ G N + P + Sbjct: 152 IVNVSESVTVNDIINLDSFQARDLDSGNNSAITYTIAPSQPFGVNQYIDEAGRPHLQLIV 211 Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE 379 TS +LD ET+ + L + ATD G PP S F ++ EL E++ Sbjct: 212 TS-ELDYETKQVHHLTLYATDNGTPPLSNNVALRILVTDANDHSPVFAQSEFVKELKENQ 270 Query: 380 PPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS---ITSQNGRGLITVAQPLDFKQERR 436 PPG + + A D D N + G+ S +T G +T+ Q LD + Sbjct: 271 PPGF-ITRVHAVDRDSGNNGRVQYFLGDESEAVSHQLVTVDKDTGDVTLVQNLDRETHDG 329 Query: 437 YVLTVSATDSGG---RSDTAMVQINITDANNYAP------VFENAPYTASVFEDAPIGTT 487 + + A DS RS + + I D N+ AP + + TA + E +PIGT Sbjct: 330 MRILIEARDSAPTNQRSSRMWLVLRIDDDNDNAPTINMNFIVDADGQTAYISEASPIGTY 389 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 V VSA+D+D G N+++ S+ + + E + FV+ G I T LDRE + Y Sbjct: 390 VAYVSASDADHGKNSEVDISIRTLVFGEPEYANTGHFVLAAD-GLIGTGLELDREIQNSY 448 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 + V ARD G S ++ + ++D NDN PVF++ +Y + E VGT+V+ V ATD Sbjct: 449 KVVVEARDAGDVPRSSFNNITVIILDENDNAPVFQKPVYPVTLSEADGVGTTVTTVSATD 508 Query: 608 ADV----------------GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA 651 D +NG++ Y +D D +F I+ +G I + LDRE + Sbjct: 509 KDALFPPVWTKNKKKEIVPSMNGKVTYLIDSDD---NTFSINAETGEITLVRPLDREGQS 565 Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI-GTTIGEIR 710 ++ +A DGG+P + ST I+ + + D+ND+ P+F + + + + + I I+ Sbjct: 566 DWEVTIIARDGGSPYKESTCILKVVVSDVNDNRPLFINPAIDNSTAYATILRDDVITRIQ 625 Query: 711 AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770 A D D + V S+ D L++ Q +D E + LD R +L + + Sbjct: 626 AVDYDSPMFSKVEISLLSVD-----GLKSTQETDGVEPYSFFVLD----RATGDLRLNMS 676 Query: 771 SPPLWNDVRVEILVTDVNDN 790 + L + V ++V DN Sbjct: 677 TADLNDIVGSHVIVVKATDN 696 Score = 157 bits (381), Expect = 4e-36 Identities = 155/609 (25%), Positives = 265/609 (43%), Gaps = 67/609 (11%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVL--TLKATDQDIGKNAEVEYTIEL 64 ++ +I + D ND++P F + +V E + + + +A D D G N+ + YTI Sbjct: 130 LNLEIVITDTNDNAPTFPHKPIIVNVSESVTVNDIINLDSFQARDLDSGNNSAITYTIAP 189 Query: 65 VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS 124 +N Q + L+ + LD E + + + ATD + Sbjct: 190 SQPFGVN---------------QYIDEAGRPHLQLIVTSELDYETKQVHHLTLYATDNGT 234 Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184 P LS+ + + + D ND+ P F++ + + E+ I ++ A D D G N Sbjct: 235 PP---LSNNVALRILVTDANDHSPVFAQSEFVKELKEN---QPPGFITRVHAVDRDSGNN 288 Query: 185 SAIRYAIIGGNTQ----MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG-SPSRSN 239 ++Y +G ++ ++D +GDV+LV+ LD E R++I A+D + RS+ Sbjct: 289 GRVQY-FLGDESEAVSHQLVTVDKDTGDVTLVQNLDRETHDGMRILIEARDSAPTNQRSS 347 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQES------VSENVPIGYSIVRVQAYDADEGVNAEL- 292 L++ I D NDNAP + ++ +SE PIG + V A DAD G N+E+ Sbjct: 348 RMWLVLRIDDDNDNAPTINMNFIVDADGQTAYISEASPIGTYVAYVSASDADHGKNSEVD 407 Query: 293 ----TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348 T + +Y + D G + T +LDRE Q Y+++V A D GD PRS+ Sbjct: 408 ISIRTLVFGEPEYANTGHFVLAAD---GLIGTGLELDREIQNSYKVVVEARDAGDVPRSS 464 Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD-------EDNRLHY 401 F Y V L+E + GT V T++ATD D N+ Sbjct: 465 FNNITVIILDENDNAPVFQKPVYPVTLSEADGVGTTVTTVSATDKDALFPPVWTKNKKKE 524 Query: 402 EITGGNTRGRFSITSQNG-------RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDT 452 + N + + I S + G IT+ +PLD + + + +T+ A D G + T Sbjct: 525 IVPSMNGKVTYLIDSDDNTFSINAETGEITLVRPLDREGQSDWEVTIIARDGGSPYKEST 584 Query: 453 AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV-VSATDSDVGINAQITYSLSSE 511 ++++ ++D N+ P+F N S + V+ + A D D + +++ SL S Sbjct: 585 CILKVVVSDVNDNRPLFINPAIDNSTAYATILRDDVITRIQAVDYDSPMFSKVEISLLSV 644 Query: 512 ISNEAVAHHD-----QQFVINPQTGAITTN-KLLD-RETMSGYLLTVTARDGGVPSLSDT 564 ++ D FV++ TG + N D + + +++ V A D G P L Sbjct: 645 DGLKSTQETDGVEPYSFFVLDRATGDLRLNMSTADLNDIVGSHVIVVKATDNGQPPLESR 704 Query: 565 TDVEISVVD 573 T + I V D Sbjct: 705 TSITIIVSD 713 Score = 137 bits (331), Expect = 5e-30 Identities = 122/400 (30%), Positives = 197/400 (49%), Gaps = 34/400 (8%) Query: 421 GLITVAQPLDFKQE----RRYVLTVSATDSGGRSDTAM-VQINITDANNYAPVFENAPYT 475 GLIT+ + +D + E + ++ V A R + + ++I ITD N+ AP F + P Sbjct: 93 GLITLRRRVDRETECGQAKECIIKVQAVMLPQRVFSLLNLEIVITDTNDNAPTFPHKPII 152 Query: 476 ASVFEDAPIGTTVLVVS--ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 +V E + + + S A D D G N+ ITY+++ + D+ P I Sbjct: 153 VNVSESVTVNDIINLDSFQARDLDSGNNSAITYTIAPSQPFGVNQYIDEAG--RPHLQLI 210 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593 T++L D ET + LT+ A D G P LS+ + I V D ND+ PVF Q + + E+ Sbjct: 211 VTSEL-DYETKQVHHLTLYATDNGTPPLSNNVALRILVTDANDHSPVFAQSEFVKELKEN 269 Query: 594 ALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFV-IDPASGVIRTNKALDRESVA 651 G +++V A D D G NGR+ Y L D + V +D +G + + LDRE Sbjct: 270 QPPGF-ITRVHAVDRDSGNNGRVQYFLGDESEAVSHQLVTVDKDTGDVTLVQNLDRE--- 325 Query: 652 THDLKAVAIDGG----TPPQSSTVIVHIKIEDINDSPP------VFESDCLTFYISENSP 701 THD + I+ T +SS + + ++I+D ND+ P + ++D T YISE SP Sbjct: 326 THDGMRILIEARDSAPTNQRSSRMWLVLRIDDDNDNAPTINMNFIVDADGQTAYISEASP 385 Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKG---GDDSNSFSLETRQGSDKAELVTMVDLDYES 758 IGT + + A D D G N+ V SI+ G+ + + +D + T ++LD E Sbjct: 386 IGTYVAYVSASDADHGKNSEVDISIRTLVFGEPEYANTGHFVLAADGL-IGTGLELDREI 444 Query: 759 PRKKYELVIRAASP---PLWNDVRVEILVTDVNDNAPVMK 795 + Y++V+ A P + + +++ D NDNAPV + Sbjct: 445 -QNSYKVVVEARDAGDVPRSSFNNITVIILDENDNAPVFQ 483 Score = 81.0 bits (191), Expect = 4e-13 Identities = 79/309 (25%), Positives = 136/309 (44%), Gaps = 23/309 (7%) Query: 612 LNGRIHYE--LDPKDREEGSFVID--PASGVIRTNKALDRESVATHDLKAVA-IDGGTPP 666 LN + H P R +D +SG+I + +DRE+ + + + P Sbjct: 64 LNQKFHSSSMFSPSARRHRPDAVDLGTSSGLITLRRRVDRETECGQAKECIIKVQAVMLP 123 Query: 667 QS--STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG--EIRAHDPDEGPNAVV 722 Q S + + I I D ND+ P F + +SE+ + I +A D D G N+ + Sbjct: 124 QRVFSLLNLEIVITDTNDNAPTFPHKPIIVNVSESVTVNDIINLDSFQARDLDSGNNSAI 183 Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVR 779 Y+I G +L+ +LDYE+ ++ + L + A +PPL N+V Sbjct: 184 TYTIAPSQPFGVNQYIDEAGRPHLQLIVTSELDYET-KQVHHLTLYATDNGTPPLSNNVA 242 Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQYRILSGNNA 837 + ILVTD ND++PV + + K+ P G RV A D D ++QY + + A Sbjct: 243 LRILVTDANDHSPVFAQSEFV-KELKENQPPGFITRVHAVDRDSGNNGRVQYFLGDESEA 301 Query: 838 ---NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG--VNEIKAMMQLSVRLITEEML 892 L+ +++ TG +TL L+ + + D N+ + M L +R+ + Sbjct: 302 VSHQLVTVDKDTGDVTLVQNLDRETHDGMRILIEARDSAPTNQRSSRMWLVLRIDDDND- 360 Query: 893 LNSITVRLN 901 N+ T+ +N Sbjct: 361 -NAPTINMN 368 >UniRef50_Q9Y5H3 Cluster: Protocadherin gamma A10 precursor; n=119; Amniota|Rep: Protocadherin gamma A10 precursor - Homo sapiens (Human) Length = 936 Score = 215 bits (524), Expect = 2e-53 Identities = 179/608 (29%), Positives = 272/608 (44%), Gaps = 32/608 (5%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +F ++ RSG+L+T +DRE++ + + V DR+ I + + D NDN P Sbjct: 78 LFSLNPRSGSLITAGRIDREELCAQSARCVVSFNIL-VEDRVKLFG-IEIEVTDINDNAP 135 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 +F + V ++E+++ + + A D DVG NS Y + N + S + Sbjct: 136 KFQAENLDVKINENVAAGMRFPLPE--AIDPDVGVNSLQSYQL-SPNKHFSLRVQSRANG 192 Query: 209 VS-----LVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263 V L +LD E+ + LV+ A DGG P RS T + + + D NDNAP F ++ Sbjct: 193 VKYPELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYR 252 Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323 SV EN+P+G ++ V A D DEG N E+TY+ + L ++ +G + S Sbjct: 253 VSVPENLPVGTQLLTVTATDRDEGANGEVTYSF--RKLPDTQLLKFQLNKYTGEIKISEN 310 Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383 LD E Y++ + A DGG ATA + ED P GT Sbjct: 311 LDYEETGFYEIEIQAEDGG--AYLATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGT 368 Query: 384 PVVTLTATDADEDNRLHYEITGGNTRG-RFSI-TSQNGRGLITVAQPLDFKQERRYVLTV 441 V L D D + + ++T F + S + + + + LD +Q Y +TV Sbjct: 369 VVALLNVHDLDSEQ--NGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITV 426 Query: 442 SATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499 +ATD G S A + + D N+ P F Y + E+ G ++ V+A D D Sbjct: 427 TATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSK 486 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 NAQI YSL+ + IN TG + + D E + VTA D G P Sbjct: 487 ENAQIIYSLAEDTIQGVPL--SSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDP 544 Query: 560 SLSDTTDVEISVVDVNDNEP-VFKQQLYTAN------IMEDALVGTSVSQVGATDADVGL 612 LS + + V+D NDN P + L T A G V++V A D D G Sbjct: 545 PLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQ 604 Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKA-LDRESVATHDLKAVAIDGGTPPQSSTV 671 N + Y L K E G F + +G +RT +A LDR+++ + AV D G PP S+TV Sbjct: 605 NAWLSYRL-LKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQ-DHGQPPLSATV 662 Query: 672 IVHIKIED 679 + + + D Sbjct: 663 TLTVAVAD 670 Score = 214 bits (522), Expect = 3e-53 Identities = 171/611 (27%), Positives = 280/611 (45%), Gaps = 32/611 (5%) Query: 194 GNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251 G TQ+ FS++ SG + +D E++ +S R V+ + + R + I + D+N Sbjct: 74 GRTQL-FSLNPRSGSLITAGRIDREELCAQSARCVV-SFNILVEDRVKLFGIEIEVTDIN 131 Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT-DKDYTGNVDLPIT 310 DNAP+F ++ENV G +A D D GVN+ +Y ++ +K ++ V Sbjct: 132 DNAPKFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRAN 191 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 + + LDRE +A + L++TA+DGGDP RS T F + Sbjct: 192 -GVKYPELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPE 250 Query: 371 YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 Y V + E+ P GT ++T+TATD DE + + Y G I +++ Sbjct: 251 YRVSVPENLPVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLLKFQLNKYTGEIKISEN 310 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 LD+++ Y + + A D G TA V I + D N+ +P + V ED+P+GT V Sbjct: 311 LDYEETGFYEIEIQAEDGGAYLATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGTVV 370 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 +++ D D N Q+T S+ + + + D + + ++ LDRE +S Y Sbjct: 371 ALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYY-------RLVIHRALDREQVSSYN 423 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 +TVTA DGG P LS + V D+NDN P F Q Y I E+ G S+ V A D Sbjct: 424 ITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDP 483 Query: 609 DVGLNGRIHYELDPKDREEG----SFV-IDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 D N +I Y L +D +G S++ I+ +GV+ ++ D E ++ A D G Sbjct: 484 DSKENAQIIYSL-AEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSG 542 Query: 664 TPPQSSTVIVHIKIEDINDSP-----PVFESDCLT--FYISENSPIGTTIGEIRAHDPDE 716 PP SS V + + + D ND+ P +D T ++ G + ++ A D D Sbjct: 543 DPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDS 602 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR-AASPPLW 775 G NA + Y + + F++ G + LD ++ ++ + ++ PPL Sbjct: 603 GQNAWLSYRLLKASEPGLFAVGEHTGEVRTARAL---LDRDALKQSLVVAVQDHGQPPLS 659 Query: 776 NDVRVEILVTD 786 V + + V D Sbjct: 660 ATVTLTVAVAD 670 Score = 192 bits (469), Expect = 9e-47 Identities = 170/597 (28%), Positives = 269/597 (45%), Gaps = 32/597 (5%) Query: 310 TIDPRSGWVYTSGQLDRETQ-AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 +++PRSG + T+G++DRE A+ V + + R F Sbjct: 80 SLNPRSGSLITAGRIDREELCAQSARCVVSFNILVEDRVKLFGIEIEVTDINDNAPKFQA 139 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQ-NGRGL--IT 424 +V++ E+ G A D D N L N + S+ NG + Sbjct: 140 ENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKHFSLRVQSRANGVKYPELV 199 Query: 425 VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 + LD ++E + L ++A+D G RS T +V + + DAN+ APVF Y SV E+ Sbjct: 200 LEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVPENL 259 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 P+GT +L V+ATD D G N ++TYS + + +F +N TG I ++ LD E Sbjct: 260 PVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQLL-----KFQLNKYTGEIKISENLDYE 314 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 Y + + A DGG + T V I+V DVNDN P + + ED+ +GT V+ Sbjct: 315 ETGFYEIEIQAEDGG--AYLATAKVLITVEDVNDNSPELTITSLFSPVTEDSPLGTVVAL 372 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 + D D NG++ + + ID ++ ++ALDRE V+++++ A DG Sbjct: 373 LNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLV-IHRALDREQVSSYNITVTATDG 431 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 G+PP S+ +++ DIND+PP F YI EN+ G +I + A DPD NA + Sbjct: 432 GSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENAQI 491 Query: 723 HYSIKGGDDSNSFSLET--RQGSDKAELVTMVDLDYESPRKKYELVIRAAS--PPLWNDV 778 YS+ D L + SD L + DYE + V + S PPL ++V Sbjct: 492 IYSL-AEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPLSSNV 550 Query: 779 RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAY----------DADVTDKLQ 828 + + V D NDNAP + + + + + P P Y D+ L Sbjct: 551 SLSLFVLDQNDNAPEIL-YPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLS 609 Query: 829 YRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSV 884 YR+L + L + E TG + + L ++ V+V D G + A + L+V Sbjct: 610 YRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTV 666 Score = 191 bits (466), Expect = 2e-46 Identities = 168/583 (28%), Positives = 268/583 (45%), Gaps = 55/583 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I V D ND++P F+ + + + E ++G +A D D+G N+ Y Sbjct: 124 EIEVTDINDNAPKFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSY--------Q 175 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 L+P VQ R +G + L+ SLDRE+ A + +++ A+D P+ Sbjct: 176 LSPN------KHFSLRVQS--RANGVKYPELVLEHSLDREEEAIHHLVLTASDGGDPLR- 226 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 S T + V + D NDN P F+ Y VSV E++ V + + ATD D GAN + Sbjct: 227 --SGTVLVSVTVFDANDNAPVFTLPEYRVSVPENLPV--GTQLLTVTATDRDEGANGEVT 282 Query: 189 YAI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 Y+ + ++F ++ +G++ + + LDYE+ Y + I+A+DGG + T ++LI Sbjct: 283 YSFRKLPDTQLLKFQLNKYTGEIKISENLDYEETGFYEIEIQAEDGG--AYLATAKVLIT 340 Query: 247 IRDVNDNAPRF-YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 + DVNDN+P TSLF V+E+ P+G + + +D D N ++T ++ Y Sbjct: 341 VEDVNDNSPELTITSLF-SPVTEDSPLGTVVALLNVHDLDSEQNGQVTCSIL--AYL-PF 396 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 L +ID V LDRE + Y + VTATDGG PP S A Sbjct: 397 KLEKSIDSYYRLVIHRA-LDREQVSSYNITVTATDGGSPPLSTEAHFMLQVADINDNPPT 455 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRG---RFSITSQNGR 420 F Y + E+ G + ++TA D D E+ ++ Y + +G I+ + Sbjct: 456 FSQVSYFTYIPENNARGASIFSVTALDPDSKENAQIIYSLAEDTIQGVPLSSYISINSDT 515 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAP--VFENAPYTA 476 G++ + D++Q + V+A+DSG S + + + D N+ AP ++ P Sbjct: 516 GVLYALRSFDYEQFHELQMQVTASDSGDPPLSSNVSLSLFVLDQNDNAPEILYPALPTDG 575 Query: 477 SV-FEDAP----IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 S E AP G V V A D D G NA ++Y L A F + TG Sbjct: 576 STGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLK-------ASEPGLFAVGEHTG 628 Query: 532 AI-TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 + T LLDR+ + L V +D G P LS T + ++V D Sbjct: 629 EVRTARALLDRDALK-QSLVVAVQDHGQPPLSATVTLTVAVAD 670 Score = 156 bits (378), Expect = 9e-36 Identities = 129/469 (27%), Positives = 208/469 (44%), Gaps = 38/469 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D ND++PVF + +Y SV E GT +LT+ ATD+D G N EV Y+ + L Sbjct: 234 VTVFDANDNAPVFTLPEYRVSVPENLPVGTQLLTVTATDRDEGANGEVTYSFRKLPDTQL 293 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F+++ +G + +LD E+ Y + ++A D + ++ Sbjct: 294 LK-----------------FQLNKYTGEIKISENLDYEETGFYEIEIQAEDGGAYLA--- 333 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 TA + + + D NDN P+ + + V ED + V+A + D D N + + Sbjct: 334 --TAKVLITVEDVNDNSPELTITSLFSPVTEDSPL--GTVVALLNVHDLDSEQNGQVTCS 389 Query: 191 IIGGNT-QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I+ +++ SIDS V + + LD EQV SY + + A DGGSP S ++ + D Sbjct: 390 ILAYLPFKLEKSIDSYYRLV-IHRALDREQVSSYNITVTATDGGSPPLSTEAHFMLQVAD 448 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NVDLP 308 +NDN P F + + EN G SI V A D D NA++ Y++ + G + Sbjct: 449 INDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENAQIIYSLAEDTIQGVPLSSY 508 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM- 367 I+I+ +G +Y D E + Q+ VTA+D GDPP S+ + + Sbjct: 509 ISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPLSSNVSLSLFVLDQNDNAPEILY 568 Query: 368 -----PGQYEVELA-EDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNG 419 G VELA PG V + A D D L Y + + G F++ G Sbjct: 569 PALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTG 628 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468 + A+ L + + L V+ D G +A V + + A++ V Sbjct: 629 E--VRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSIPQV 675 Score = 78.2 bits (184), Expect = 3e-12 Identities = 58/247 (23%), Positives = 101/247 (40%), Gaps = 22/247 (8%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 H + V D ND+ P F Y + E + G ++ ++ A D D +NA++ Y++ Sbjct: 441 HFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKENAQIIYSL---AE 497 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 DT+ + I+ +G L S D E+ + V A+D P Sbjct: 498 DTIQ-----------GVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDP-- 544 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI-----SVTDNPVIAKIKATDADVG 182 LSS ++ + ++D NDN P+ + S ++ K+ A D D G Sbjct: 545 -PLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSG 603 Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 N+ + Y ++ + F++ +G+V + L LV+ QD G P S T Sbjct: 604 QNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVT 663 Query: 243 LLINIRD 249 L + + D Sbjct: 664 LTVAVAD 670 >UniRef50_UPI00004F6724 Cluster: protocadherin 1 gamma 1; n=3; Danio rerio|Rep: protocadherin 1 gamma 1 - Danio rerio Length = 932 Score = 214 bits (522), Expect = 3e-53 Identities = 164/561 (29%), Positives = 256/561 (45%), Gaps = 33/561 (5%) Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195 I + + D NDN P F + + + + E + +A D DVG NS Y + + Sbjct: 116 IALEVQDVNDNPPVFPKGSIKLEISEGAPTGSK--LQLTRARDLDVGINSVQTYIL---S 170 Query: 196 TQMQFSIDSLSG-----DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 F +D+ S D+ L +LD E + L++ A DGG+P S T + + + D+ Sbjct: 171 QNKHFVLDTKSSKDRYVDIVLKNSLDRETRGEHSLILSAVDGGNPPNSGTVVIEVVVIDM 230 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDNAP F L+ +SEN +G S++++ A D DEG N E+ Y + + N Sbjct: 231 NDNAPLFSQPLYNARLSENSALGTSVIKITATDEDEGANGEIKYYI--NHLSDNTKQLFK 288 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 ID G + GQLD E + Y++ V A DGG ++ Sbjct: 289 IDENYGEISVIGQLDHEKASSYEVEVQAEDGGG--QTGHCKVVIEIDDVNDNAPVISVKS 346 Query: 371 YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQ-NGRGLITVAQ 427 + ++ E+ PGT + + D D E++R+ I+ F + ++T + Sbjct: 347 LKNKIPENTTPGTEIAVINVKDQDSGENSRISCSISPNLP---FQLQPYIKSYFILTTSS 403 Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAMVQINI--TDANNYAPVFENAPYTASVFEDAPIG 485 LD +Q Y +T+ ATD G + + +NI +D N+ +P FE Y + E+ G Sbjct: 404 SLDREQIDNYNVTIIATDGGIPPLFSNISLNIQVSDVNDNSPRFELHSYFIYISENKQAG 463 Query: 486 TTVLVVSATDSDVGINAQITYSL-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 T+V VSA D D N + YSL SE++ ++ IN TG I T + D E Sbjct: 464 TSVCSVSANDPDWRQNGTVLYSLVPSEVNGVPMSSF---LSINGDTGVIHTVRSFDYEQF 520 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF------KQQLYTANIMEDALVGT 598 + + V ARD G P LS V++ + D NDN P + L T + + L G+ Sbjct: 521 RNFSVKVVARDNGSPPLSSNVTVKVFITDENDNSPQILYPVPDGKSLMTEMVPKATLSGS 580 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 VS+V A DAD G N + Y++ K + G F I SG I+T + + +L Sbjct: 581 LVSKVIAVDADSGQNAWLSYQI-LKSTDPGLFTIGLHSGEIKTQRDISESDNMKQNLVIS 639 Query: 659 AIDGGTPPQSSTVIVHIKIED 679 D G P S+T +V++ I D Sbjct: 640 VKDNGQPSLSTTCVVNLLISD 660 Score = 209 bits (511), Expect = 7e-52 Identities = 171/605 (28%), Positives = 281/605 (46%), Gaps = 57/605 (9%) Query: 4 PFCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 P +H + V D ND+ PVF + + EGA +G+ + +A D D+G N+ Y + Sbjct: 110 PLELHNIALEVQDVNDNPPVFPKGSIKLEISEGAPTGSKLQLTRARDLDVGINSVQTYIL 169 Query: 63 ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122 L+ + + +D + +D ++ + SLDRE +++++ A D Sbjct: 170 SQNKHFVLDTKSS-----------KDRY-VD-----IVLKNSLDRETRGEHSLILSAVDG 212 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 +P + S T I V +ID NDN P FS+ Y + E+ ++ + + KI ATD D G Sbjct: 213 GNPPN---SGTVVIEVVVIDMNDNAPLFSQPLYNARLSENSALGTS--VIKITATDEDEG 267 Query: 183 ANSAIRYAI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240 AN I+Y I + NT+ F ID G++S++ LD+E+ SY + ++A+DGG ++ Sbjct: 268 ANGEIKYYINHLSDNTKQLFKIDENYGEISVIGQLDHEKASSYEVEVQAEDGG--GQTGH 325 Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 +++I I DVNDNAP + + EN G I + D D G N+ ++ +++ Sbjct: 326 CKVVIEIDDVNDNAPVISVKSLKNKIPENTTPGTEIAVINVKDQDSGENSRISCSISP-- 383 Query: 301 YTGNVDLPITIDP--RSGWVY-TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357 +LP + P +S ++ TS LDRE Y + + ATDGG PP + + Sbjct: 384 -----NLPFQLQPYIKSYFILTTSSSLDREQIDNYNVTIIATDGGIPPLFSNISLNIQVS 438 Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRG--RFS 413 F Y + ++E++ GT V +++A D D ++ + Y + G S Sbjct: 439 DVNDNSPRFELHSYFIYISENKQAGTSVCSVSANDPDWRQNGTVLYSLVPSEVNGVPMSS 498 Query: 414 ITSQNG-RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAP-VF 469 S NG G+I + D++Q R + + V A D+G S V++ ITD N+ +P + Sbjct: 499 FLSINGDTGVIHTVRSFDYEQFRNFSVKVVARDNGSPPLSSNVTVKVFITDENDNSPQIL 558 Query: 470 ENAPYTASVF-EDAP----IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524 P S+ E P G+ V V A D+D G NA ++Y + F Sbjct: 559 YPVPDGKSLMTEMVPKATLSGSLVSKVIAVDADSGQNAWLSYQILKSTD-------PGLF 611 Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584 I +G I T + + L ++ +D G PSLS T V + + D P K Sbjct: 612 TIGLHSGEIKTQRDISESDNMKQNLVISVKDNGQPSLSTTCVVNLLISDNLSEVPELKDM 671 Query: 585 LYTAN 589 Y N Sbjct: 672 SYEDN 676 Score = 206 bits (502), Expect = 9e-51 Identities = 163/573 (28%), Positives = 260/573 (45%), Gaps = 26/573 (4%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQNGRGL-I 423 F G ++E++E P G+ + A D D N + I N S R + I Sbjct: 130 FPKGSIKLEISEGAPTGSKLQLTRARDLDVGINSVQTYILSQNKHFVLDTKSSKDRYVDI 189 Query: 424 TVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFED 481 + LD + + L +SA D G S T ++++ + D N+ AP+F Y A + E+ Sbjct: 190 VLKNSLDRETRGEHSLILSAVDGGNPPNSGTVVIEVVVIDMNDNAPLFSQPLYNARLSEN 249 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 + +GT+V+ ++ATD D G N +I Y ++ N Q F I+ G I+ LD Sbjct: 250 SALGTSVIKITATDEDEGANGEIKYYINHLSDNTK-----QLFKIDENYGEISVIGQLDH 304 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 E S Y + V A DGG + V I + DVNDN PV + I E+ GT ++ Sbjct: 305 EKASSYEVEVQAEDGG--GQTGHCKVVIEIDDVNDNAPVISVKSLKNKIPENTTPGTEIA 362 Query: 602 QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 + D D G N RI + P + I + ++ T+ +LDRE + +++ +A D Sbjct: 363 VINVKDQDSGENSRISCSISPNLPFQLQPYIK-SYFILTTSSSLDREQIDNYNVTIIATD 421 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 GG PP S + ++I++ D+ND+ P FE YISEN GT++ + A+DPD N Sbjct: 422 GGIPPLFSNISLNIQVSDVNDNSPRFELHSYFIYISENKQAGTSVCSVSANDPDWRQNGT 481 Query: 722 VHYSIKGGD-DSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIR-AASPPLWNDV 778 V YS+ + + S D + T+ DYE R ++V R SPPL ++V Sbjct: 482 VLYSLVPSEVNGVPMSSFLSINGDTGVIHTVRSFDYEQFRNFSVKVVARDNGSPPLSSNV 541 Query: 779 RVEILVTDVNDNAP----VMKDFQIIFNNY--KDCFPVGPFGRVPAYDADVTDK--LQYR 830 V++ +TD NDN+P + D + + K +V A DAD L Y+ Sbjct: 542 TVKVFITDENDNSPQILYPVPDGKSLMTEMVPKATLSGSLVSKVIAVDADSGQNAWLSYQ 601 Query: 831 ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEE 890 IL + L + +G + ++ + + +SV D + V L+ + Sbjct: 602 ILKSTDPGLFTIGLHSGEIKTQRDISESDNMKQNLVISVKDN-GQPSLSTTCVVNLLISD 660 Query: 891 MLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAI 923 L S L DM+ E S L + I L ++ Sbjct: 661 NL--SEVPELKDMSYEDNNSKLTSYLIIALVSV 691 Score = 171 bits (416), Expect = 2e-40 Identities = 118/342 (34%), Positives = 171/342 (50%), Gaps = 16/342 (4%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 + + + D N+ PVF + E AP G+ + + A D DVGIN+ TY LS Sbjct: 116 IALEVQDVNDNPPVFPKGSIKLEISEGAPTGSKLQLTRARDLDVGINSVQTYILSQNKHF 175 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 + ++ I LDRET + L ++A DGG P S T +E+ V+D+ Sbjct: 176 VLDTKSSKDRYVD-----IVLKNSLDRETRGEHSLILSAVDGGNPPNSGTVVIEVVVIDM 230 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP-KDREEGSFVID 633 NDN P+F Q LY A + E++ +GTSV ++ ATD D G NG I Y ++ D + F ID Sbjct: 231 NDNAPLFSQPLYNARLSENSALGTSVIKITATDEDEGANGEIKYYINHLSDNTKQLFKID 290 Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693 G I LD E ++++++ A DGG Q+ V I+I+D+ND+ PV L Sbjct: 291 ENYGEISVIGQLDHEKASSYEVEVQAEDGG--GQTGHCKVVIEIDDVNDNAPVISVKSLK 348 Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753 I EN+ GT I I D D G N+ + SI + F L+ S L T Sbjct: 349 NKIPENTTPGTEIAVINVKDQDSGENSRISCSI---SPNLPFQLQPYIKS-YFILTTSSS 404 Query: 754 LDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAP 792 LD E Y + I A PPL++++ + I V+DVNDN+P Sbjct: 405 LDREQ-IDNYNVTIIATDGGIPPLFSNISLNIQVSDVNDNSP 445 Score = 123 bits (296), Expect = 8e-26 Identities = 87/278 (31%), Positives = 135/278 (48%), Gaps = 18/278 (6%) Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584 I+ +G + ++ +DRE + G + + + + ++ + V DVNDN PVF + Sbjct: 74 IDLDSGDLFVSERIDREMLCGTASPCIMHFEFILENPLELHNIALEVQDVNDNPPVFPKG 133 Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR---- 640 I E A G+ + A D DVG+N Y L + FV+D S R Sbjct: 134 SIKLEISEGAPTGSKLQLTRARDLDVGINSVQTYILS----QNKHFVLDTKSSKDRYVDI 189 Query: 641 -TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699 +LDRE+ H L A+DGG PP S TV++ + + D+ND+ P+F +SEN Sbjct: 190 VLKNSLDRETRGEHSLILSAVDGGNPPNSGTVVIEVVVIDMNDNAPLFSQPLYNARLSEN 249 Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS--FSLETRQGSDKAELVTMVDLDYE 757 S +GT++ +I A D DEG N + Y I D+ F ++ G E+ + LD+E Sbjct: 250 SALGTSVIKITATDEDEGANGEIKYYINHLSDNTKQLFKIDENYG----EISVIGQLDHE 305 Query: 758 SPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAPVM 794 YE+ ++A +V I + DVNDNAPV+ Sbjct: 306 K-ASSYEVEVQAEDGGGQTGHCKVVIEIDDVNDNAPVI 342 Score = 95.1 bits (226), Expect = 2e-17 Identities = 76/268 (28%), Positives = 118/268 (44%), Gaps = 25/268 (9%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 I I V D ND+SP FE+ Y + E +GT+V ++ A D D +N V Y+ Sbjct: 431 ISLNIQVSDVNDNSPRFELHSYFIYISENKQAGTSVCSVSANDPDWRQNGTVLYS----- 485 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 L P + + I+G +G + T S D E+ ++V V A D SP Sbjct: 486 ---LVPSEVNGVP------MSSFLSINGDTGVIHTVRSFDYEQFRNFSVKVVARDNGSPP 536 Query: 127 SDRLSSTATIHVNIIDDNDNYPQF------SEKTYTVSVDEDISVTDNPVIAKIKATDAD 180 LSS T+ V I D+NDN PQ + T V + + +++K+ A DAD Sbjct: 537 ---LSSNVTVKVFITDENDNSPQILYPVPDGKSLMTEMVPK--ATLSGSLVSKVIAVDAD 591 Query: 181 VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240 G N+ + Y I+ F+I SG++ + + LVI +D G PS S T Sbjct: 592 SGQNAWLSYQILKSTDPGLFTIGLHSGEIKTQRDISESDNMKQNLVISVKDNGQPSLSTT 651 Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSE 268 + + I D P ++++ S+ Sbjct: 652 CVVNLLISDNLSEVPELKDMSYEDNNSK 679 >UniRef50_P73089 Cluster: Fat protein; n=1; Synechocystis sp. PCC 6803|Rep: Fat protein - Synechocystis sp. (strain PCC 6803) Length = 1965 Score = 214 bits (522), Expect = 3e-53 Identities = 201/789 (25%), Positives = 355/789 (44%), Gaps = 41/789 (5%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F + G+S L L+ E A YTV V D + L++ + +N +D+ P Sbjct: 684 FEVIGQSLFLKAGTVLNFESKASYTVTVNVDDDTVGSTPDLTADFKLTINNLDEVA--PT 741 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209 + ++ E+ N +I ++KATD D ++ I + + G+ F I++ +G+V Sbjct: 742 ITSGDTAKAIAENSGA--NQIIYQVKATD-DGDISAGITFGLKPGDDADSFIINATTGEV 798 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIRDVNDNAPRFYTSLFQESVSE 268 L+ D+E SY+ + A DG +P+ T QL+ + I D+++ AP + ++++E Sbjct: 799 KLIGNPDFETQSSYKFTVTADDGVNPA---TEQLVNLAIIDLDEIAPTITSGDTAKAIAE 855 Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328 N I +V A D D V+A +T+ + + + DL I I+ +G V + D ET Sbjct: 856 NSGANQVIYQVTATD-DADVSAGITFGLKPGN---DADLFI-INSTTGQVILTENPDFET 910 Query: 329 QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388 Q+ Y+ VTA+DG +P T G + E+ + + Sbjct: 911 QSSYKFTVTASDGVNPATEKIVT--LAIIDLDEIAPTITSGDTAKAITENSGANQVIYEV 968 Query: 389 TAT-DADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447 AT DAD + + + GN G F+I G+ +T+ DF+ + Y TV+A+D Sbjct: 969 IATDDADVSAGITFGLKPGNDAGSFTINPITGK--VTLIDDPDFETQSSYKFTVTASDGV 1026 Query: 448 GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507 + +V + I D + AP + ++ E++ + V ATD D ++A IT+ Sbjct: 1027 NLATEQLVNLTIIDLDEIAPTITSGDTAKAIAENSGANQVIYEVIATD-DADVSAGITFG 1085 Query: 508 LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567 L N+A F INP TG +T D ET S Y TVTA DG +L+ V Sbjct: 1086 LKP--GNDA-----GSFTINPITGKVTLIDDPDFETQSSYKFTVTASDG--VNLATEQLV 1136 Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627 ++++D+++ P I E++ + Q A D + ++ + + L P D + Sbjct: 1137 NLTIIDLDEIAPTITSGDTAKAITENSGANQIIYQATADD-NADISAGVTFGLKPGD-DA 1194 Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687 SF+I+ +G + D E+ +++ A DG P +V++ I D+++ P Sbjct: 1195 DSFIINAITGQVTLLDNPDFETQSSYKFTVTASDGVNPVTEQ--VVNLTIIDLDEIAPTI 1252 Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747 S I+ENS I ++ A D D +A V + +K GDD+ SFS+++ G K Sbjct: 1253 TSGNTAKAIAENSGANQVIYQVTATD-DADISAEVTFGLKLGDDATSFSIDSTTG--KVT 1309 Query: 748 LVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMK--DFQIIFNNYK 805 L+ D + +S K +P + V + + ++++ P + D + Sbjct: 1310 LINNPDFESQSSYKFTVTASDGVNPA--TEKIVTLAINNLDEIGPTITSGDTATPIDENS 1367 Query: 806 DCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATM 865 + + + DADV+ + + + GN+A +N TG +TL + Sbjct: 1368 GANQL-IYQVIATDDADVSAGITFGLKPGNDAGSFTINPITGEVTLIDDPDFETQSSYKF 1426 Query: 866 EVSVTDGVN 874 V+ +DGVN Sbjct: 1427 TVTASDGVN 1435 Score = 210 bits (513), Expect = 4e-52 Identities = 213/861 (24%), Positives = 392/861 (45%), Gaps = 49/861 (5%) Query: 43 LTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR 102 +T T + I +N+ I VTA A D+F I+ +G ++ Sbjct: 844 ITSGDTAKAIAENSGANQVIYQVTATDDADVSAGITFGLKPGNDADLFIINSTTGQVILT 903 Query: 103 ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162 + D E + Y V A+D +P ++++ + A IID ++ P + ++ E+ Sbjct: 904 ENPDFETQSSYKFTVTASDGVNPATEKIVTLA-----IIDLDEIAPTITSGDTAKAITEN 958 Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222 N VI ++ ATD D ++ I + + GN F+I+ ++G V+L+ D+E S Sbjct: 959 SGA--NQVIYEVIATD-DADVSAGITFGLKPGNDAGSFTINPITGKVTLIDDPDFETQSS 1015 Query: 223 YRLVIRAQDGGSPSRSNTTQLL-INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA 281 Y+ + A DG + + T QL+ + I D+++ AP + ++++EN I V A Sbjct: 1016 YKFTVTASDGVNLA---TEQLVNLTIIDLDEIAPTITSGDTAKAIAENSGANQVIYEVIA 1072 Query: 282 YDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG 341 D D V+A +T+ + + G+ TI+P +G V D ETQ+ Y+ VTA+DG Sbjct: 1073 TD-DADVSAGITFGLKPGNDAGS----FTINPITGKVTLIDDPDFETQSSYKFTVTASDG 1127 Query: 342 GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD-ADEDNRLH 400 + + G + E+ + TA D AD + Sbjct: 1128 VN--LATEQLVNLTIIDLDEIAPTITSGDTAKAITENSGANQIIYQATADDNADISAGVT 1185 Query: 401 YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT 460 + + G+ F I + G+ +T+ DF+ + Y TV+A+D +V + I Sbjct: 1186 FGLKPGDDADSFIINAITGQ--VTLLDNPDFETQSSYKFTVTASDGVNPVTEQVVNLTII 1243 Query: 461 DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520 D + AP + ++ E++ + V+ATD D I+A++T+ L ++ ++A + Sbjct: 1244 DLDEIAPTITSGNTAKAIAENSGANQVIYQVTATD-DADISAEVTFGL--KLGDDATS-- 1298 Query: 521 DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580 F I+ TG +T D E+ S Y TVTA DG P+ V +++ ++++ P Sbjct: 1299 ---FSIDSTTGKVTLINNPDFESQSSYKFTVTASDGVNPATEKI--VTLAINNLDEIGPT 1353 Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640 I E++ + QV ATD D ++ I + L P + + GSF I+P +G + Sbjct: 1354 ITSGDTATPIDENSGANQLIYQVIATD-DADVSAGITFGLKPGN-DAGSFTINPITGEVT 1411 Query: 641 TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700 D E+ +++ A DG P ++ IV + I D+++ P SD + I+ENS Sbjct: 1412 LIDDPDFETQSSYKFTVTASDGVNP--ATEKIVTLTINDLDELGPNITSDNIATAINENS 1469 Query: 701 PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDL-DYESP 759 I ++ A D D+ +A V + +K GD++N FS++ G VT++D D+E+ Sbjct: 1470 GANQIIYQVTADDGDD-ISAGVTFGLKPGDNANQFSIDPTTGQ-----VTLLDNPDFET- 1522 Query: 760 RKKYELVIRAASP--PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVP 817 + Y+ + A+ P + V + + D+++ AP + ++ +V Sbjct: 1523 QSSYKFTVTASDGVNPATEQL-VNLTIIDLDEIAPTITSGDTAKAIAENSGANQVIYQVT 1581 Query: 818 AYD-ADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEI 876 A D AD + + + + G +AN +N TG + L + V+ +DGVN + Sbjct: 1582 ATDDADTSAGVTFGLKPGEDANSFTINAATGEVELIGNPDFETQSSYKFTVTASDGVNPV 1641 Query: 877 KAMMQLSVRLITEEMLLNSIT 897 + +++ +I + + +IT Sbjct: 1642 TEQV-VNLTIIDLDEIAPTIT 1661 Score = 209 bits (511), Expect = 7e-52 Identities = 201/792 (25%), Positives = 355/792 (44%), Gaps = 46/792 (5%) Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 D F I+ +G + + D E + Y V A D +P +++L +++ IID ++ Sbjct: 787 DSFIINATTGEVKLIGNPDFETQSSYKFTVTADDGVNPATEQL-----VNLAIIDLDEIA 841 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 P + ++ E+ N VI ++ ATD D ++ I + + GN F I+S +G Sbjct: 842 PTITSGDTAKAIAENSGA--NQVIYQVTATD-DADVSAGITFGLKPGNDADLFIINSTTG 898 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 V L + D+E SY+ + A DG +P+ L I D+++ AP + ++++ Sbjct: 899 QVILTENPDFETQSSYKFTVTASDGVNPATEKIVTLA--IIDLDEIAPTITSGDTAKAIT 956 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 EN I V A D D V+A +T+ + + G+ TI+P +G V D E Sbjct: 957 ENSGANQVIYEVIATD-DADVSAGITFGLKPGNDAGS----FTINPITGKVTLIDDPDFE 1011 Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387 TQ+ Y+ VTA+DG + + G +AE+ + Sbjct: 1012 TQSSYKFTVTASDGVN--LATEQLVNLTIIDLDEIAPTITSGDTAKAIAENSGANQVIYE 1069 Query: 388 LTAT-DADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446 + AT DAD + + + GN G F+I G+ +T+ DF+ + Y TV+A+D Sbjct: 1070 VIATDDADVSAGITFGLKPGNDAGSFTINPITGK--VTLIDDPDFETQSSYKFTVTASDG 1127 Query: 447 GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT-DSDVGINAQIT 505 + +V + I D + AP + ++ E++ G ++ AT D + I+A +T Sbjct: 1128 VNLATEQLVNLTIIDLDEIAPTITSGDTAKAITENS--GANQIIYQATADDNADISAGVT 1185 Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTT 565 + L ++A F+IN TG +T D ET S Y TVTA DG P Sbjct: 1186 FGLKP--GDDA-----DSFIINAITGQVTLLDNPDFETQSSYKFTVTASDGVNPVTEQV- 1237 Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625 V ++++D+++ P I E++ + QV ATD D ++ + + L D Sbjct: 1238 -VNLTIIDLDEIAPTITSGNTAKAIAENSGANQVIYQVTATD-DADISAEVTFGLKLGD- 1294 Query: 626 EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685 + SF ID +G + D ES +++ A DG P ++ IV + I ++++ P Sbjct: 1295 DATSFSIDSTTGKVTLINNPDFESQSSYKFTVTASDGVNP--ATEKIVTLAINNLDEIGP 1352 Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745 S I ENS I ++ A D D +A + + +K G+D+ SF++ G Sbjct: 1353 TITSGDTATPIDENSGANQLIYQVIATD-DADVSAGITFGLKPGNDAGSFTINPITG--- 1408 Query: 746 AELVTMVDLDYESPRKKYELVIRAAS--PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN 803 E+ + D D+E+ + Y+ + A+ P + V + + D+++ P + I Sbjct: 1409 -EVTLIDDPDFET-QSSYKFTVTASDGVNPATEKI-VTLTINDLDELGPNITSDNIATAI 1465 Query: 804 YKDCFPVGPFGRVPAYDA-DVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKL 862 ++ +V A D D++ + + + G+NAN ++ TTG +TL + Sbjct: 1466 NENSGANQIIYQVTADDGDDISAGVTFGLKPGDNANQFSIDPTTGQVTLLDNPDFETQSS 1525 Query: 863 ATMEVSVTDGVN 874 V+ +DGVN Sbjct: 1526 YKFTVTASDGVN 1537 Score = 202 bits (492), Expect = 1e-49 Identities = 198/805 (24%), Positives = 362/805 (44%), Gaps = 43/805 (5%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F I+ +G + D E + Y V A+D + +++L +++ IID ++ P Sbjct: 993 FTINPITGKVTLIDDPDFETQSSYKFTVTASDGVNLATEQL-----VNLTIIDLDEIAPT 1047 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209 + ++ E+ N VI ++ ATD D ++ I + + GN F+I+ ++G V Sbjct: 1048 ITSGDTAKAIAENSGA--NQVIYEVIATD-DADVSAGITFGLKPGNDAGSFTINPITGKV 1104 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL-INIRDVNDNAPRFYTSLFQESVSE 268 +L+ D+E SY+ + A DG + + T QL+ + I D+++ AP + ++++E Sbjct: 1105 TLIDDPDFETQSSYKFTVTASDGVNLA---TEQLVNLTIIDLDEIAPTITSGDTAKAITE 1161 Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328 N I + A D + ++A +T+ + D + I+ +G V D ET Sbjct: 1162 NSGANQIIYQATA-DDNADISAGVTFGLKPGDDADS----FIINAITGQVTLLDNPDFET 1216 Query: 329 QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388 Q+ Y+ VTA+DG +P G +AE+ + + Sbjct: 1217 QSSYKFTVTASDGVNPVTEQVVNLTIIDLDEIAPTIT--SGNTAKAIAENSGANQVIYQV 1274 Query: 389 TATD-ADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447 TATD AD + + + G+ FSI S G+ +T+ DF+ + Y TV+A+D Sbjct: 1275 TATDDADISAEVTFGLKLGDDATSFSIDSTTGK--VTLINNPDFESQSSYKFTVTASDGV 1332 Query: 448 GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507 + +V + I + + P + + E++ + V ATD D ++A IT+ Sbjct: 1333 NPATEKIVTLAINNLDEIGPTITSGDTATPIDENSGANQLIYQVIATD-DADVSAGITFG 1391 Query: 508 LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567 L N+A + F INP TG +T D ET S Y TVTA DG P+ V Sbjct: 1392 LKP--GNDAGS-----FTINPITGEVTLIDDPDFETQSSYKFTVTASDGVNPATEKI--V 1442 Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627 +++ D+++ P I E++ + QV A D D ++ + + L P D Sbjct: 1443 TLTINDLDELGPNITSDNIATAINENSGANQIIYQVTADDGD-DISAGVTFGLKPGDNAN 1501 Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687 F IDP +G + D E+ +++ A DG P ++ +V++ I D+++ P Sbjct: 1502 -QFSIDPTTGQVTLLDNPDFETQSSYKFTVTASDGVNP--ATEQLVNLTIIDLDEIAPTI 1558 Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747 S I+ENS I ++ A D D +A V + +K G+D+NSF++ G + E Sbjct: 1559 TSGDTAKAIAENSGANQVIYQVTATD-DADTSAGVTFGLKPGEDANSFTINAATG--EVE 1615 Query: 748 LVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC 807 L+ D + +S K + + P+ V V + + D+++ AP + ++ Sbjct: 1616 LIGNPDFETQSSYK-FTVTASDGVNPVTEQV-VNLTIIDLDEIAPTITSGNTAKAIAENS 1673 Query: 808 FPVGPFGRVPAYD-ADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATME 866 +V A D AD++ + + + G++A ++ TTG +TL + Sbjct: 1674 GANQVIYQVTATDDADISAGVTFGLKPGDDATSFSIDSTTGKVTLINNPDFESQSSYRFT 1733 Query: 867 VSVTDGVNEIKAMMQLSVRLITEEM 891 V+ DGVN + Q+++ ++ + + Sbjct: 1734 VTADDGVNPV-TEQQIALEILDDNV 1757 Score = 192 bits (468), Expect = 1e-46 Identities = 178/709 (25%), Positives = 316/709 (44%), Gaps = 43/709 (6%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F I+ +G + D E + Y V A+D + +++L +++ IID ++ P Sbjct: 1095 FTINPITGKVTLIDDPDFETQSSYKFTVTASDGVNLATEQL-----VNLTIIDLDEIAPT 1149 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATD-ADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 + ++ E+ N +I + A D AD+ A + + + G+ F I++++G Sbjct: 1150 ITSGDTAKAITENSGA--NQIIYQATADDNADISAG--VTFGLKPGDDADSFIINAITGQ 1205 Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268 V+L+ D+E SY+ + A DG +P L I D+++ AP + ++++E Sbjct: 1206 VTLLDNPDFETQSSYKFTVTASDGVNPVTEQVVNL--TIIDLDEIAPTITSGNTAKAIAE 1263 Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328 N I +V A D D ++AE+T+ + G+ +ID +G V D E+ Sbjct: 1264 NSGANQVIYQVTATD-DADISAEVTFGLK----LGDDATSFSIDSTTGKVTLINNPDFES 1318 Query: 329 QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388 Q+ Y+ VTA+DG +P T G + E+ + + Sbjct: 1319 QSSYKFTVTASDGVNPATEKIVTLAINNLDEIGPTIT--SGDTATPIDENSGANQLIYQV 1376 Query: 389 TATD-ADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447 ATD AD + + + GN G F+I G +T+ DF+ + Y TV+A+D Sbjct: 1377 IATDDADVSAGITFGLKPGNDAGSFTINPITGE--VTLIDDPDFETQSSYKFTVTASDGV 1434 Query: 448 GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507 + +V + I D + P + ++ E++ + V+A D D I+A +T+ Sbjct: 1435 NPATEKIVTLTINDLDELGPNITSDNIATAINENSGANQIIYQVTADDGD-DISAGVTFG 1493 Query: 508 LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567 L + QF I+P TG +T D ET S Y TVTA DG P+ V Sbjct: 1494 LKP-------GDNANQFSIDPTTGQVTLLDNPDFETQSSYKFTVTASDGVNPATEQL--V 1544 Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627 ++++D+++ P I E++ + QV ATD D + + + L P + + Sbjct: 1545 NLTIIDLDEIAPTITSGDTAKAIAENSGANQVIYQVTATD-DADTSAGVTFGLKPGE-DA 1602 Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687 SF I+ A+G + D E+ +++ A DG P +V++ I D+++ P Sbjct: 1603 NSFTINAATGEVELIGNPDFETQSSYKFTVTASDGVNPVTEQ--VVNLTIIDLDEIAPTI 1660 Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAE 747 S I+ENS I ++ A D D +A V + +K GDD+ SFS+++ G K Sbjct: 1661 TSGNTAKAIAENSGANQVIYQVTATD-DADISAGVTFGLKPGDDATSFSIDSTTG--KVT 1717 Query: 748 LVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKD 796 L+ D + +S + +P + +EIL +DN V+++ Sbjct: 1718 LINNPDFESQSSYRFTVTADDGVNPVTEQQIALEIL----DDNVAVIEN 1762 Score = 173 bits (422), Expect = 4e-41 Identities = 158/639 (24%), Positives = 275/639 (43%), Gaps = 32/639 (5%) Query: 43 LTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR 102 +T T + I +N+ I TAD A D F I+ +G + Sbjct: 1150 ITSGDTAKAITENSGANQIIYQATADDNADISAGVTFGLKPGDDADSFIINAITGQVTLL 1209 Query: 103 ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162 + D E + Y V A+D +PV++++ +++ IID ++ P + ++ E+ Sbjct: 1210 DNPDFETQSSYKFTVTASDGVNPVTEQV-----VNLTIIDLDEIAPTITSGNTAKAIAEN 1264 Query: 163 ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS 222 N VI ++ ATD D ++ + + + G+ FSIDS +G V+L+ D+E S Sbjct: 1265 SGA--NQVIYQVTATD-DADISAEVTFGLKLGDDATSFSIDSTTGKVTLINNPDFESQSS 1321 Query: 223 YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY 282 Y+ + A DG +P+ L IN ++++ P + + EN I +V A Sbjct: 1322 YKFTVTASDGVNPATEKIVTLAIN--NLDEIGPTITSGDTATPIDENSGANQLIYQVIAT 1379 Query: 283 DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG 342 D D V+A +T+ + + G+ TI+P +G V D ETQ+ Y+ VTA+DG Sbjct: 1380 D-DADVSAGITFGLKPGNDAGS----FTINPITGEVTLIDDPDFETQSSYKFTVTASDGV 1434 Query: 343 DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR-LHY 401 +P T + E+ + +TA D D+ + + + Sbjct: 1435 NPATEKIVT--LTINDLDELGPNITSDNIATAINENSGANQIIYQVTADDGDDISAGVTF 1492 Query: 402 EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITD 461 + G+ +FSI G+ +T+ DF+ + Y TV+A+D + +V + I D Sbjct: 1493 GLKPGDNANQFSIDPTTGQ--VTLLDNPDFETQSSYKFTVTASDGVNPATEQLVNLTIID 1550 Query: 462 ANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521 + AP + ++ E++ + V+ATD D +A +T+ L Sbjct: 1551 LDEIAPTITSGDTAKAIAENSGANQVIYQVTATD-DADTSAGVTFGLKP-------GEDA 1602 Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581 F IN TG + D ET S Y TVTA DG P V ++++D+++ P Sbjct: 1603 NSFTINAATGEVELIGNPDFETQSSYKFTVTASDGVNPVTEQV--VNLTIIDLDEIAPTI 1660 Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641 I E++ + QV ATD D ++ + + L P D + SF ID +G + Sbjct: 1661 TSGNTAKAIAENSGANQVIYQVTATD-DADISAGVTFGLKPGD-DATSFSIDSTTGKVTL 1718 Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680 D ES +++ A DG P + + I +++ Sbjct: 1719 INNPDFESQSSYRFTVTADDGVNPVTEQQIALEILDDNV 1757 Score = 137 bits (332), Expect = 4e-30 Identities = 139/580 (23%), Positives = 258/580 (44%), Gaps = 31/580 (5%) Query: 324 LDRETQAKYQLLVTATDG--GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381 L+ E++A Y + V D G P TA G +AE+ Sbjct: 699 LNFESKASYTVTVNVDDDTVGSTP-DLTADFKLTINNLDEVAPTITSGDTAKAIAENSGA 757 Query: 382 GTPVVTLTATD-ADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440 + + ATD D + + + G+ F I + G + + P DF+ + Y T Sbjct: 758 NQIIYQVKATDDGDISAGITFGLKPGDDADSFIINATTGEVKL-IGNP-DFETQSSYKFT 815 Query: 441 VSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 V+A D + +V + I D + AP + ++ E++ + V+ATD D + Sbjct: 816 VTADDGVNPATEQLVNLAIIDLDEIAPTITSGDTAKAIAENSGANQVIYQVTATD-DADV 874 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560 +A IT+ L N+A F+IN TG + + D ET S Y TVTA DG P+ Sbjct: 875 SAGITFGLKP--GNDA-----DLFIINSTTGQVILTENPDFETQSSYKFTVTASDGVNPA 927 Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620 V ++++D+++ P I E++ + +V ATD D ++ I + L Sbjct: 928 TEKI--VTLAIIDLDEIAPTITSGDTAKAITENSGANQVIYEVIATD-DADVSAGITFGL 984 Query: 621 DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680 P + + GSF I+P +G + D E+ +++ A DG ++ +V++ I D+ Sbjct: 985 KPGN-DAGSFTINPITGKVTLIDDPDFETQSSYKFTVTASDGVN--LATEQLVNLTIIDL 1041 Query: 681 NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR 740 ++ P S I+ENS I E+ A D D +A + + +K G+D+ SF++ Sbjct: 1042 DEIAPTITSGDTAKAIAENSGANQVIYEVIATD-DADVSAGITFGLKPGNDAGSFTINPI 1100 Query: 741 QGSDKAELVTMVD-LDYESPRKKYELVIRAASPP-LWNDVRVEILVTDVNDNAPVMKDFQ 798 G VT++D D+E+ + Y+ + A+ L + V + + D+++ AP + Sbjct: 1101 TGK-----VTLIDDPDFET-QSSYKFTVTASDGVNLATEQLVNLTIIDLDEIAPTITSGD 1154 Query: 799 IIFNNYKDCFPVGPFGRVPAYD-ADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNT 857 ++ + A D AD++ + + + G++A+ ++N TG +TL + Sbjct: 1155 TAKAITENSGANQIIYQATADDNADISAGVTFGLKPGDDADSFIINAITGQVTLLDNPDF 1214 Query: 858 NVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSIT 897 V+ +DGVN + + +++ +I + + +IT Sbjct: 1215 ETQSSYKFTVTASDGVNPVTEQV-VNLTIIDLDEIAPTIT 1253 >UniRef50_UPI0000E80EB2 Cluster: PREDICTED: hypothetical protein; n=1; Gallus gallus|Rep: PREDICTED: hypothetical protein - Gallus gallus Length = 1259 Score = 213 bits (521), Expect = 4e-53 Identities = 166/584 (28%), Positives = 268/584 (45%), Gaps = 27/584 (4%) Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195 + V ++D ND+ P F + Y + V E S A D DVG NS Y + N Sbjct: 420 VEVEVLDINDHAPTFPWQEYVLEVAE--SAVLGARFPLESAQDPDVGTNSVHTYQL-SPN 476 Query: 196 TQMQFSIDSLS-----GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + + + S ++ L + LD EQ R++RL++ A DGG P RS T +L+ + D Sbjct: 477 SFFSLEVHTRSDASKFAELVLERALDREQQRTHRLLLTALDGGIPRRSGTAHVLVTVLDA 536 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F + S+ E+ P G ++++ A D DEG N E+ Y+ + +L Sbjct: 537 NDNIPAFDQPSYGVSLPEDAPAGTLVIQLNATDLDEGPNGEIEYSFSGHAPPSVREL-FR 595 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 ++PRSG V G LD E + ++L V A D G + Sbjct: 596 VEPRSGQVLLKGPLDYERASLHELYVQAKDRGPSAVAVHCRVLVHLLDVNDNAPEVTLTS 655 Query: 371 YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 + ED PPGT + ++ D D ++ R+ E++ + + ++ L+T +P Sbjct: 656 VSTPVQEDAPPGTVIAVISVLDRDSGDNGRVSCELS-PSVPFELRSSFRDYYTLVT-TEP 713 Query: 429 LDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 LD + Y ++++A D G + + + + ++D N+ AP F Y+ V E+ G Sbjct: 714 LDREAVSEYNISITARDMGSPALLTRSTLTVPVSDVNDNAPHFLQPSYSVYVMENNAPGA 773 Query: 487 TVLVVSATDSDVGINAQITYSLS-SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 ++ VSA D D NA ++YS++ I V + IN +G + + LD E + Sbjct: 774 SICSVSALDPDCQQNAYLSYSITDGHIHGMPVGTY---VSINSDSGHMYALRSLDYEQIR 830 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF------KQQLYTANIMEDALVGTS 599 + + V A+D G P LS V I V+D NDN PV + T + A G Sbjct: 831 SFQIQVQAQDAGFPPLSANVTVHIFVLDQNDNAPVIVSPMPRNGSVATELVPRSAGPGYL 890 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 V V A DAD GLN R+ Y+L + + F + P +G +RT ++ + A L Sbjct: 891 VGTVSAVDADAGLNSRLSYQL-LQATDFTLFSLAPDTGELRTLRSFLEQDAARQRLVVQV 949 Query: 660 IDGGTPPQSSTVIVHIK-IEDINDSPPVFESDCLTFYISENSPI 702 DGG P S+TV + + +E + + F + L S +SP+ Sbjct: 950 RDGGQPALSATVSLLLSVVETMPQTLSDFSNFSLPPEASSSSPL 993 Score = 209 bits (511), Expect = 7e-52 Identities = 169/583 (28%), Positives = 264/583 (45%), Gaps = 53/583 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ VLD NDH+P F Q+Y V E A G A D D+G N+ Y Sbjct: 421 EVEVLDINDHAPTFPWQEYVLEVAESAVLGARFPLESAQDPDVGTNSVHTYQ-------- 472 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L+P + L+ +LDRE+ + +L+ A D P R Sbjct: 473 LSPNSFFSLEVHTRSDAS-------KFAELVLERALDREQQRTHRLLLTALDGGIP---R 522 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S TA + V ++D NDN P F + +Y VS+ ED ++ ++ ATD D G N I Y Sbjct: 523 RSGTAHVLVTVLDANDNIPAFDQPSYGVSLPEDAPA--GTLVIQLNATDLDEGPNGEIEY 580 Query: 190 AIIG---GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 + G + + F ++ SG V L LDYE+ + L ++A+D G + + ++L++ Sbjct: 581 SFSGHAPPSVRELFRVEPRSGQVLLKGPLDYERASLHELYVQAKDRGPSAVAVHCRVLVH 640 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + DVNDNAP + V E+ P G I + D D G N ++ ++ +V Sbjct: 641 LLDVNDNAPEVTLTSVSTPVQEDAPPGTVIAVISVLDRDSGDNGRVSCELSP-----SVP 695 Query: 307 LPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 + R + + T+ LDRE ++Y + +TA D G P +T Sbjct: 696 FELRSSFRDYYTLVTTEPLDREAVSEYNISITARDMGSPALLTRSTLTVPVSDVNDNAPH 755 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGR-----FSITSQN 418 F+ Y V + E+ PG + +++A D D ++ L Y IT G+ G SI S + Sbjct: 756 FLQPSYSVYVMENNAPGASICSVSALDPDCQQNAYLSYSITDGHIHGMPVGTYVSINSDS 815 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFEN-APYT 475 G + + LD++Q R + + V A D+G S V I + D N+ APV + P Sbjct: 816 GH--MYALRSLDYEQIRSFQIQVQAQDAGFPPLSANVTVHIFVLDQNDNAPVIVSPMPRN 873 Query: 476 ASVFED-----APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 SV + A G V VSA D+D G+N++++Y L A F + P T Sbjct: 874 GSVATELVPRSAGPGYLVGTVSAVDADAGLNSRLSYQLLQ-------ATDFTLFSLAPDT 926 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 G + T + + + L V RDGG P+LS T + +SVV+ Sbjct: 927 GELRTLRSFLEQDAARQRLVVQVRDGGQPALSATVSLLLSVVE 969 Score = 194 bits (474), Expect = 2e-47 Identities = 158/522 (30%), Positives = 245/522 (46%), Gaps = 26/522 (4%) Query: 370 QYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQNGRGL---ITV 425 +Y +E+AE G +A D D N +H N+ + +++ + + Sbjct: 438 EYVLEVAESAVLGARFPLESAQDPDVGTNSVHTYQLSPNSFFSLEVHTRSDASKFAELVL 497 Query: 426 AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 + LD +Q+R + L ++A D G RS TA V + + DAN+ P F+ Y S+ EDAP Sbjct: 498 ERALDREQQRTHRLLLTALDGGIPRRSGTAHVLVTVLDANDNIPAFDQPSYGVSLPEDAP 557 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 GT V+ ++ATD D G N +I YS S A + F + P++G + LD E Sbjct: 558 AGTLVIQLNATDLDEGPNGEIEYSFSGH----APPSVRELFRVEPRSGQVLLKGPLDYER 613 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 S + L V A+D G +++ V + ++DVNDN P + + EDA GT ++ + Sbjct: 614 ASLHELYVQAKDRGPSAVAVHCRVLVHLLDVNDNAPEVTLTSVSTPVQEDAPPGTVIAVI 673 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 D D G NGR+ EL P E ++ T + LDRE+V+ +++ A D G Sbjct: 674 SVLDRDSGDNGRVSCELSPSVPFELRSSFRDYYTLV-TTEPLDREAVSEYNISITARDMG 732 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 +P + + + + D+ND+ P F + Y+ EN+ G +I + A DPD NA + Sbjct: 733 SPALLTRSTLTVPVSDVNDNAPHFLQPSYSVYVMENNAPGASICSVSALDPDCQQNAYLS 792 Query: 724 YSIKGGD-DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVR 779 YSI G SD + + LDYE R +++ ++A PPL +V Sbjct: 793 YSITDGHIHGMPVGTYVSINSDSGHMYALRSLDYEQIR-SFQIQVQAQDAGFPPLSANVT 851 Query: 780 VEILVTDVNDNAPV-MKDFQIIFNNYKDCFP--VGP---FGRVPAYDAD--VTDKLQYRI 831 V I V D NDNAPV + + + P GP G V A DAD + +L Y++ Sbjct: 852 VHIFVLDQNDNAPVIVSPMPRNGSVATELVPRSAGPGYLVGTVSAVDADAGLNSRLSYQL 911 Query: 832 LSGNNANLILLNETTGSM-TLSPQLNTNVPKLATMEVSVTDG 872 L + L L TG + TL L + + + V V DG Sbjct: 912 LQATDFTLFSLAPDTGELRTLRSFLEQDAAR-QRLVVQVRDG 952 Score = 173 bits (420), Expect = 8e-41 Identities = 152/486 (31%), Positives = 220/486 (45%), Gaps = 45/486 (9%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 H + VLD ND+ P F+ Y S+ E A +GT V+ L ATD D G N E+EY+ Sbjct: 528 HVLVTVLDANDNIPAFDQPSYGVSLPEDAPAGTLVIQLNATDLDEGPNGEIEYSFS---- 583 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 V+++FR++ RSG +L + LD E+ + + + V+A D+ P + Sbjct: 584 ------------GHAPPSVRELFRVEPRSGQVLLKGPLDYERASLHELYVQAKDR-GPSA 630 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 + +H ++D NDN P+ + + + V ED VIA I D D G N + Sbjct: 631 VAVHCRVLVH--LLDVNDNAPEVTLTSVSTPVQED--APPGTVIAVISVLDRDSGDNGRV 686 Query: 188 RYAIIGGNTQMQFSIDSLSGD-VSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 + + + F + S D +LV T LD E V Y + I A+D GSP+ + L Sbjct: 687 SCEL---SPSVPFELRSSFRDYYTLVTTEPLDREAVSEYNISITARDMGSPALLTRSTLT 743 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG- 303 + + DVNDNAP F + V EN G SI V A D D NA L+Y++TD G Sbjct: 744 VPVSDVNDNAPHFLQPSYSVYVMENNAPGASICSVSALDPDCQQNAYLSYSITDGHIHGM 803 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 V ++I+ SG +Y LD E +Q+ V A D G PP SA T Sbjct: 804 PVGTYVSINSDSGHMYALRSLDYEQIRSFQIQVQAQDAGFPPLSANVTVHIFVLDQNDNA 863 Query: 364 XXF---MP--GQYEVELA-EDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSIT 415 MP G EL PG V T++A DAD ++RL Y++ FS+ Sbjct: 864 PVIVSPMPRNGSVATELVPRSAGPGYLVGTVSAVDADAGLNSRLSYQLLQATDFTLFSLA 923 Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYT 475 G L T+ L+ + R L V D G + +A V + ++ V E P T Sbjct: 924 PDTGE-LRTLRSFLE-QDAARQRLVVQVRDGGQPALSATVSLLLS-------VVETMPQT 974 Query: 476 ASVFED 481 S F + Sbjct: 975 LSDFSN 980 Score = 162 bits (393), Expect = 1e-37 Identities = 121/348 (34%), Positives = 163/348 (46%), Gaps = 23/348 (6%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS--SEI 512 V++ + D N++AP F Y V E A +G + SA D DVG N+ TY LS S Sbjct: 420 VEVEVLDINDHAPTFPWQEYVLEVAESAVLGARFPLESAQDPDVGTNSVHTYQLSPNSFF 479 Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572 S E D + + + LDRE + L +TA DGG+P S T V ++V+ Sbjct: 480 SLEVHTRSDAS-----KFAELVLERALDREQQRTHRLLLTALDGGIPRRSGTAHVLVTVL 534 Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD----PKDREEG 628 D NDN P F Q Y ++ EDA GT V Q+ ATD D G NG I Y P RE Sbjct: 535 DANDNIPAFDQPSYGVSLPEDAPAGTLVIQLNATDLDEGPNGEIEYSFSGHAPPSVRE-- 592 Query: 629 SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688 F ++P SG + LD E + H+L A D G + V + + D+ND+ P Sbjct: 593 LFRVEPRSGQVLLKGPLDYERASLHELYVQAKDRGPSAVAVHCRVLVHLLDVNDNAPEVT 652 Query: 689 SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG-SDKAE 747 ++ + E++P GT I I D D G N V + S S E R D Sbjct: 653 LTSVSTPVQEDAPPGTVIAVISVLDRDSGDNGRVSCEL-----SPSVPFELRSSFRDYYT 707 Query: 748 LVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792 LVT LD E+ +Y + I A SP L + + V+DVNDNAP Sbjct: 708 LVTTEPLDREAV-SEYNISITARDMGSPALLTRSTLTVPVSDVNDNAP 754 >UniRef50_Q9VFH5 Cluster: CG3389-PA; n=2; Sophophora|Rep: CG3389-PA - Drosophila melanogaster (Fruit fly) Length = 2002 Score = 213 bits (521), Expect = 4e-53 Identities = 206/745 (27%), Positives = 325/745 (43%), Gaps = 78/745 (10%) Query: 88 DVFRID---GRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDN 144 ++ RI+ G + LDRE Y +++ TD S SD T + + + D N Sbjct: 109 EIIRIENTGGNEAKIFLAKELDRELQDEYAIVLTLTD--SHYSDHNYVTQSFLLLVEDIN 166 Query: 145 DNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY---AIIGGNTQMQFS 201 DN P F + + E + V++ ++ATDAD GA + Y + G N + Sbjct: 167 DNVPTFLPYQNAIEIPEGSAPG---VVSTLEATDADEGAYGQVVYYLQELDGDNDVFSIA 223 Query: 202 IDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGS--PSRSNTTQLLINIRDVNDNAPRFYT 259 G + L K LDYE+ Y+L + A D + P + T +L+ ++D+ D P F Sbjct: 224 THQGKGILRLQKELDYERKSLYQLRVLAIDRANQGPINTGTAAILVKVKDLEDQPPEFVE 283 Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319 ++E+ P+G ++RV+A D D G+N + Y++ D I+P +G V+ Sbjct: 284 VQAVARIAEDAPVGTKVLRVRAIDGDRGINNPIAYSLEANDL-------FDINPHTGIVH 336 Query: 320 TSGQLDRETQA-----KYQLLVTATD-GGDPPRSATATXXXXXXXXXXXXXXFMP--GQ- 370 T +LDRE Q+ + L ++AT+ + A T +P G+ Sbjct: 337 TLTKLDREEQSDQVNGAHILRISATELSKSNTQMAPTTVRTEVTVIVSDVNDEIPTFGET 396 Query: 371 -YEVELAEDEPPGTPV------VTLTATDADEDNRLHYEITGGNTRGRFSITSQ------ 417 Y E+ E+ TP+ V D DE N + + F I + Sbjct: 397 VYRCEVNENAQTNTPLNFIDEEVQNVVFDHDEGNNGTFRLFLDPPNDLFEIVPELAVNEA 456 Query: 418 NGRGLITVAQPLDFKQ--ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYT 475 N + ++ LDF+Q E + + D R +A VQI I D N+ P F Y Sbjct: 457 NFMLRVKNSKSLDFEQFTEVNFTIFAREVDEPSRWSSAHVQIFIRDQNDNFPEFSQTIYN 516 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 ASV E++ T + V A D D G T + +AH +NP TG IT Sbjct: 517 ASVLENSEQDTIITHVQAVDVDSGDYG--TMGIRYTNLRGGIAH---LLNLNPITGVITI 571 Query: 536 NK----LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 + DRE +S + LTV A D +T + + ++DVNDN P F Q+ Y ++ Sbjct: 572 KQAGGTAFDREIISRHYLTVEAIDNAGQGNRNTAQIIVDILDVNDNAPTFPQRQYETKLL 631 Query: 592 EDALVGTSVSQVGATDADVG--LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE- 648 E+ + Q+ A DAD+ N ++ YE+ + +F IDP SG++R + D E Sbjct: 632 ENQAEFETPLQLEARDADLNGTENSQVTYEI-VEGLYRSNFTIDPQSGLLRPVHSFDFEE 690 Query: 649 -----------------SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691 S+ DL A D G P S+ V V I ++D+ND+ P+F+ Sbjct: 691 LVDGSSRRSDPYTGGSFSIREIDLLVRARDSGIPMLSTVVPVLIYVQDVNDNAPIFQQSF 750 Query: 692 LTFYISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750 + E+ P G+++ ++ A D D PN VV Y I+ G + F + + G Sbjct: 751 YAKTVPEDLPGGSSVLQVTAIDRDGSAPNNVVVYRIQTG-AGDKFIINSETGVISVAHGA 809 Query: 751 MVDLDY-ESPRKKYEL-VIRAASPP 773 +D D ES R Y L V+R+ P Sbjct: 810 NLDPDLTESKRSLYTLSVVRSKEIP 834 Score = 212 bits (517), Expect = 1e-52 Identities = 210/783 (26%), Positives = 354/783 (45%), Gaps = 77/783 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD-IGKNAEVEYTIELVTADT 69 I V D ND++P+F+ Y +V E G++VL + A D+D N V Y I+ D Sbjct: 734 IYVQDVNDNAPIFQQSFYAKTVPEDLPGGSSVLQVTAIDRDGSAPNNVVVYRIQTGAGDK 793 Query: 70 --LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV- 126 +N E D+ S L S+ R K + ++K P Sbjct: 794 FIINSETGVISVAHGANLDPDLTE----SKRSLYTLSVVRSKEIPFCRILKPFRNCLPQI 849 Query: 127 -------SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDA 179 + +L +T T++++I D N+ P E + + E+ V ++ +I+ATD Sbjct: 850 ALDGGLGNSQLMTTCTVNISIQDVNNKPPVLKEMP-ALQILENTPV--GTLVYRIQATDL 906 Query: 180 DVGANSAIRYAI----IGGNTQM-------------QFSIDSLSGDVSLVKTLDYEQVRS 222 D A +RY + G T+ F +DS+ G + +VK LD E+V Sbjct: 907 DHKA--ILRYKLNPEHCEGRTEEGALVKSSEYDFLGAFEVDSIEGTLKVVKLLDRERVEH 964 Query: 223 YRLVIRAQDGGSPSRSNTTQ--LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQ 280 +L I +D + + L I + D NDN P+F +++S++EN G IV V Sbjct: 965 IKLAITVEDLAAAKGRQIAEGFLSIQVLDENDNNPKFRLPFYRQSITENSINGAMIVNVL 1024 Query: 281 AYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD 340 A D D+ N +TY + ++ + +DP++G + + ++D E V ATD Sbjct: 1025 ASDVDK--NRTITYALEGNPTYRSL---MHLDPQTGEIVVASKIDHEQHQWLNFSVRATD 1079 Query: 341 GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--R 398 G P RS+ F+ G ++E+ PGT V TL A DAD + + Sbjct: 1080 SGIPARSSLVDVYITVLDENDNNPYFVGGSKNYTISENAAPGTRVATLQAGDADSGDFGK 1139 Query: 399 LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS------GGRSDT 452 + + + +++G+F+I + G++TVA LD + + Y L + A D+ G S Sbjct: 1140 ITFLMDRISSQGKFTIDADT--GVLTVADRLDRESKDSYNLVIEAWDNYQFGFLAGESRN 1197 Query: 453 AMVQ--INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD--VGINAQITYSL 508 A Q I+I D N+ P + + E + V + D+D N ++ +++ Sbjct: 1198 AFKQVFISILDENDNPPEVDLPMSCVLITEYHELHERVASIVGKDADDPTTPNGRLDFAI 1257 Query: 509 SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568 + N+ +Q I+ I +K L R Y LT+T RD G+P+ ++ Sbjct: 1258 TR--GNKDGMFELRQ--IDAWNAQIFASKSL-RNRYGNYSLTITTRDMGLPANIVHNTLD 1312 Query: 569 ISVVDVNDNEPVFKQQLY--TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD-R 625 I V D ND+ PVF + L+ T I E+A VGT + Q A+D D+G N + Y L P Sbjct: 1313 ICVSDFNDHAPVFVRPLHNTTVRIPENATVGTLILQAYASDGDMGQNALVRYRLKPDPLG 1372 Query: 626 EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSP 684 F +D ++G + + L+RE H+++ A D G P SS + + I + ++ND Sbjct: 1373 SYKMFEVDGSTGELFLKEQLNREKQKIHEIRIEAYDQGLPTSLSSDLDLTIYVRNVNDYE 1432 Query: 685 PVFESDCLTFYISENSPIGT-------TI--GEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735 P F + ++ +E+S G+ TI ++ DP++ P+ V Y I G+++ F Sbjct: 1433 PQFMVNEISVNFTEHSDPGSERIKLPDTIDKDQLELDDPNDTPSQVC-YFIVNGNEAGYF 1491 Query: 736 SLE 738 L+ Sbjct: 1492 RLD 1494 Score = 202 bits (493), Expect = 1e-49 Identities = 206/739 (27%), Positives = 321/739 (43%), Gaps = 96/739 (12%) Query: 104 SLDREKVAR--YTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDE 161 SLD E+ +T+ + D+ S R SS A + + I D NDN+P+FS+ Y SV E Sbjct: 467 SLDFEQFTEVNFTIFAREVDEPS----RWSS-AHVQIFIRDQNDNFPEFSQTIYNASVLE 521 Query: 162 DISVTDNPVIAKIKATDADVG--ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT----L 215 + + +I ++A D D G IRY + G +++ ++G +++ + Sbjct: 522 NSE--QDTIITHVQAVDVDSGDYGTMGIRYTNLRGGIAHLLNLNPITGVITIKQAGGTAF 579 Query: 216 DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275 D E + + L + A D NT Q++++I DVNDNAP F ++ + EN + Sbjct: 580 DREIISRHYLTVEAIDNAGQGNRNTAQIIVDILDVNDNAPTFPQRQYETKLLENQAEFET 639 Query: 276 IVRVQAYDAD-EGV-NAELTYTMTDKDYTGNVDLPITIDPRSGWVY-------------T 320 ++++A DAD G N+++TY + + Y N TIDP+SG + + Sbjct: 640 PLQLEARDADLNGTENSQVTYEIVEGLYRSN----FTIDPQSGLLRPVHSFDFEELVDGS 695 Query: 321 SGQLDRETQAKYQ-----LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375 S + D T + LLV A D G P S F Y + Sbjct: 696 SRRSDPYTGGSFSIREIDLLVRARDSGIPMLSTVVPVLIYVQDVNDNAPIFQQSFYAKTV 755 Query: 376 AEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL--- 429 ED P G+ V+ +TA D D +N + Y I G +F I S+ G +I+VA Sbjct: 756 PEDLPGGSSVLQVTAIDRDGSAPNNVVVYRIQTG-AGDKFIINSETG--VISVAHGANLD 812 Query: 430 -DFKQERRYVLTVS-----------------------ATDSG-GRSD---TAMVQINITD 461 D + +R + T+S A D G G S T V I+I D Sbjct: 813 PDLTESKRSLYTLSVVRSKEIPFCRILKPFRNCLPQIALDGGLGNSQLMTTCTVNISIQD 872 Query: 462 ANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD------VGINAQITYSLSSEISNE 515 NN PV + P + E+ P+GT V + ATD D +N + + E + Sbjct: 873 VNNKPPVLKEMP-ALQILENTPVGTLVYRIQATDLDHKAILRYKLNPEHCEGRTEEGALV 931 Query: 516 AVAHHD--QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD--VEISV 571 + +D F ++ G + KLLDRE + L +T D + + I V Sbjct: 932 KSSEYDFLGAFEVDSIEGTLKVVKLLDRERVEHIKLAITVEDLAAAKGRQIAEGFLSIQV 991 Query: 572 VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631 +D NDN P F+ Y +I E+++ G + V A+D D N I Y L+ Sbjct: 992 LDENDNNPKFRLPFYRQSITENSINGAMIVNVLASDVD--KNRTITYALEGNPTYRSLMH 1049 Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691 +DP +G I +D E + A D G P +SS V V+I + D ND+ P F Sbjct: 1050 LDPQTGEIVVASKIDHEQHQWLNFSVRATDSGIPARSSLVDVYITVLDENDNNPYFVGGS 1109 Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751 + ISEN+ GT + ++A D D G + + + F+++ G ++T+ Sbjct: 1110 KNYTISENAAPGTRVATLQAGDADSGDFGKITFLMDRISSQGKFTIDADTG-----VLTV 1164 Query: 752 VD-LDYESPRKKYELVIRA 769 D LD ES + Y LVI A Sbjct: 1165 ADRLDRES-KDSYNLVIEA 1182 Score = 192 bits (469), Expect = 9e-47 Identities = 251/934 (26%), Positives = 388/934 (41%), Gaps = 121/934 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D D P F Q A + E A GT VL ++A D D G N + Y++E + Sbjct: 269 VKVKDLEDQPPEFVEVQAVARIAEDAPVGTKVLRVRAIDGDRGINNPIAYSLEANDLFDI 328 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 NP + + D +GA + R S T L K+ Q +P + R Sbjct: 329 NPHTGIVHTLTKLDREE---QSDQVNGAHILRISA--------TELSKSNTQMAPTTVRT 377 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTD--NPVIAKIKAT--DADVGANSA 186 T V + D ND P F E Y V+E+ N + +++ D D G N Sbjct: 378 EVT----VIVSDVNDEIPTFGETVYRCEVNENAQTNTPLNFIDEEVQNVVFDHDEGNNGT 433 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLV------KTLDYEQVRSYRLVIRAQDGGSPSRSNT 240 R + N + + + + + K+LD+EQ I A++ PSR ++ Sbjct: 434 FRLFLDPPNDLFEIVPELAVNEANFMLRVKNSKSLDFEQFTEVNFTIFAREVDEPSRWSS 493 Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 + I IRD NDN P F +++ SV EN I VQA D D G + T + Sbjct: 494 AHVQIFIRDQNDNFPEFSQTIYNASVLENSEQDTIITHVQAVDVDSGDYGTMGIRYT--N 551 Query: 301 YTGNVDLPITIDPRSGWVYTSGQ-----LDRETQAKYQLLVTATDGGDPPRSATATXXXX 355 G + + ++P +G V T Q DRE +++ L V A D TA Sbjct: 552 LRGGIAHLLNLNPITG-VITIKQAGGTAFDREIISRHYLTVEAIDNAGQGNRNTAQIIVD 610 Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD----EDNRLHYEITGGNTRGR 411 F QYE +L E++ + L A DAD E++++ YEI G R Sbjct: 611 ILDVNDNAPTFPQRQYETKLLENQAEFETPLQLEARDADLNGTENSQVTYEIVEGLYRSN 670 Query: 412 FSITSQNGRGLITVAQPLDFKQ-----ERR---YV----------LTVSATDSG--GRSD 451 F+I Q+ GL+ DF++ RR Y L V A DSG S Sbjct: 671 FTIDPQS--GLLRPVHSFDFEELVDGSSRRSDPYTGGSFSIREIDLLVRARDSGIPMLST 728 Query: 452 TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI-NAQITYSLSS 510 V I + D N+ AP+F+ + Y +V ED P G++VL V+A D D N + Y + + Sbjct: 729 VVPVLIYVQDVNDNAPIFQQSFYAKTVPEDLPGGSSVLQVTAIDRDGSAPNNVVVYRIQT 788 Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT------------------ 552 ++ + + + VI+ GA + L S Y L+V Sbjct: 789 GAGDKFII-NSETGVISVAHGA-NLDPDLTESKRSLYTLSVVRSKEIPFCRILKPFRNCL 846 Query: 553 ---ARDGGV--PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 A DGG+ L T V IS+ DVN+ PV K ++ I+E+ VGT V ++ ATD Sbjct: 847 PQIALDGGLGNSQLMTTCTVNISIQDVNNKPPVLK-EMPALQILENTPVGTLVYRIQATD 905 Query: 608 ADVGLNGRIHYELDPKDREE----------------GSFVIDPASGVIRTNKALDRESVA 651 D + Y+L+P+ E G+F +D G ++ K LDRE V Sbjct: 906 LD--HKAILRYKLNPEHCEGRTEEGALVKSSEYDFLGAFEVDSIEGTLKVVKLLDRERV- 962 Query: 652 THDLKAVAID---GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 H A+ ++ Q + + I++ D ND+ P F I+ENS G I Sbjct: 963 EHIKLAITVEDLAAAKGRQIAEGFLSIQVLDENDNNPKFRLPFYRQSITENSINGAMIVN 1022 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNS-FSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 + A D D+ N + Y+++G S L+ + G E+V +D+E + + Sbjct: 1023 VLASDVDK--NRTITYALEGNPTYRSLMHLDPQTG----EIVVASKIDHEQ-HQWLNFSV 1075 Query: 768 RAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVT 824 RA P + V V I V D NDN P + ++ P + A DAD Sbjct: 1076 RATDSGIPARSSLVDVYITVLDENDNNPYFVGGSKNYTISENAAPGTRVATLQAGDADSG 1135 Query: 825 D--KLQYRILSGNNANLILLNETTGSMTLSPQLN 856 D K+ + + ++ ++ TG +T++ +L+ Sbjct: 1136 DFGKITFLMDRISSQGKFTIDADTGVLTVADRLD 1169 Score = 161 bits (392), Expect = 2e-37 Identities = 160/567 (28%), Positives = 248/567 (43%), Gaps = 52/567 (9%) Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326 S +G I ++ YD D N LT+ + + + + T ++ + +LDR Sbjct: 76 SPETKVGTLIYTLKGYDPD---NDPLTFGKRNSHDSEIIRIENT-GGNEAKIFLAKELDR 131 Query: 327 ETQAKYQLLVTATDGGDPPRS-ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 E Q +Y +++T TD + T + F+P Q +E+ E PG V Sbjct: 132 ELQDEYAIVLTLTDSHYSDHNYVTQSFLLLVEDINDNVPTFLPYQNAIEIPEGSAPGV-V 190 Query: 386 VTLTATDADED---NRLHY--EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440 TL ATDADE ++Y E+ G N FSI + G+G++ + + LD++++ Y L Sbjct: 191 STLEATDADEGAYGQVVYYLQELDGDNDV--FSIATHQGKGILRLQKELDYERKSLYQLR 248 Query: 441 VSATDSGGR----SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496 V A D + + TA + + + D + P F A + EDAP+GT VL V A D Sbjct: 249 VLAIDRANQGPINTGTAAILVKVKDLEDQPPEFVEVQAVARIAEDAPVGTKVLRVRAIDG 308 Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS-----GYLLTV 551 D GIN I YSL + + F INP TG + T LDRE S ++L + Sbjct: 309 DRGINNPIAYSLEA----------NDLFDINPHTGIVHTLTKLDREEQSDQVNGAHILRI 358 Query: 552 TARDGGVPS--LSDTT---DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 +A + + ++ TT +V + V DVND P F + +Y + E+A T ++ + Sbjct: 359 SATELSKSNTQMAPTTVRTEVTVIVSDVNDEIPTFGETVYRCEVNENAQTNTPLNFIDEE 418 Query: 607 ------DADVGLNGRIHYELDP-KDREE--GSFVIDPASGVIRT--NKALDRESVATHDL 655 D D G NG LDP D E ++ A+ ++R +K+LD E + Sbjct: 419 VQNVVFDHDEGNNGTFRLFLDPPNDLFEIVPELAVNEANFMLRVKNSKSLDFEQFTEVNF 478 Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 A + P + S+ V I I D ND+ P F + ENS T I ++A D D Sbjct: 479 TIFAREVDEPSRWSSAHVQIFIRDQNDNFPEFSQTIYNASVLENSEQDTIITHVQAVDVD 538 Query: 716 EGPNAV--VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV--IRAAS 771 G + Y+ G ++ +L G + D E + Y V I A Sbjct: 539 SGDYGTMGIRYTNLRGGIAHLLNLNPITGVITIKQAGGTAFDREIISRHYLTVEAIDNAG 598 Query: 772 PPLWNDVRVEILVTDVNDNAPVMKDFQ 798 N ++ + + DVNDNAP Q Sbjct: 599 QGNRNTAQIIVDILDVNDNAPTFPQRQ 625 Score = 159 bits (387), Expect = 8e-37 Identities = 185/678 (27%), Positives = 289/678 (42%), Gaps = 87/678 (12%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72 V D ND+ P F Q + EG++ G V TL+ATD D G +V Y ++ + D Sbjct: 162 VEDINDNVPTFLPYQNAIEIPEGSAPG-VVSTLEATDADEGAYGQVVYYLQELDGD---- 216 Query: 73 EDAXXXXXXXXXXVQDVFRIDGR--SGALLTRASLDREKVARYTVLVKATDQAS--PVSD 128 DVF I G L + LD E+ + Y + V A D+A+ P++ Sbjct: 217 --------------NDVFSIATHQGKGILRLQKELDYERKSLYQLRVLAIDRANQGPIN- 261 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 + TA I V + D D P+F E + ED V + +++A D D G N+ I Sbjct: 262 --TGTAAILVKVKDLEDQPPEFVEVQAVARIAEDAPV--GTKVLRVRAIDGDRGINNPIA 317 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY--RLVIRAQDGGSPSRSNT------ 240 Y++ + F I+ +G V + LD E+ I S+SNT Sbjct: 318 YSLEANDL---FDINPHTGIVHTLTKLDREEQSDQVNGAHILRISATELSKSNTQMAPTT 374 Query: 241 --TQLLINIRDVNDNAPRFYTSLFQESVSE----NVPIGYSIVRVQ--AYDADEGVNAEL 292 T++ + + DVND P F ++++ V+E N P+ + VQ +D DEG N Sbjct: 375 VRTEVTVIVSDVNDEIPTFGETVYRCEVNENAQTNTPLNFIDEEVQNVVFDHDEGNNGTF 434 Query: 293 TYTMTDKDYTGNVDLPITIDPRSGW--VYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350 + + + + ++ + V S LD E + + A + +P R ++A Sbjct: 435 RLFLDPPNDLFEIVPELAVNEANFMLRVKNSKSLDFEQFTEVNFTIFAREVDEPSRWSSA 494 Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG 410 F Y + E+ T + + A D D + I N RG Sbjct: 495 HVQIFIRDQNDNFPEFSQTIYNASVLENSEQDTIITHVQAVDVDSGDYGTMGIRYTNLRG 554 Query: 411 RFS-ITSQNG-RGLITVAQP--LDFKQE--RRYVLTVSATDSGGRS--DTAMVQINITDA 462 + + + N G+IT+ Q F +E R+ LTV A D+ G+ +TA + ++I D Sbjct: 555 GIAHLLNLNPITGVITIKQAGGTAFDREIISRHYLTVEAIDNAGQGNRNTAQIIVDILDV 614 Query: 463 NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG--INAQITYSLSSEISNEAVAHH 520 N+ AP F Y + E+ T L + A D+D+ N+Q+TY + + + Sbjct: 615 NDNAPTFPQRQYETKLLENQAEFETPLQLEARDADLNGTENSQVTYEIVEGL-------Y 667 Query: 521 DQQFVINPQTGAITTNKLLD-RETMSG-------YL----------LTVTARDGGVPSLS 562 F I+PQ+G + D E + G Y L V ARD G+P LS Sbjct: 668 RSNFTIDPQSGLLRPVHSFDFEELVDGSSRRSDPYTGGSFSIREIDLLVRARDSGIPMLS 727 Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL-NGRIHYELD 621 V I V DVNDN P+F+Q Y + ED G+SV QV A D D N + Y + Sbjct: 728 TVVPVLIYVQDVNDNAPIFQQSFYAKTVPEDLPGGSSVLQVTAIDRDGSAPNNVVVYRIQ 787 Query: 622 PKDREEGSFVIDPASGVI 639 ++ F+I+ +GVI Sbjct: 788 TGAGDK--FIINSETGVI 803 Score = 155 bits (375), Expect = 2e-35 Identities = 189/718 (26%), Positives = 299/718 (41%), Gaps = 72/718 (10%) Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ-LLINIRDVNDNAPRFYTSLFQESVS 267 + L K LD E Y +V+ D + TQ L+ + D+NDN P F + Sbjct: 123 IFLAKELDRELQDEYAIVLTLTDSHYSDHNYVTQSFLLLVEDINDNVPTFLPYQNAIEIP 182 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 E G + ++A DADEG ++ Y + + D +V I G + +LD E Sbjct: 183 EGSAPGV-VSTLEATDADEGAYGQVVYYLQELDGDNDV-FSIATHQGKGILRLQKELDYE 240 Query: 328 TQAKYQLLVTATDGGD--PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 ++ YQL V A D + P + TA F+ Q +AED P GT V Sbjct: 241 RKSLYQLRVLAIDRANQGPINTGTAAILVKVKDLEDQPPEFVEVQAVARIAEDAPVGTKV 300 Query: 386 VTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER-----RYV 438 + + A D D +N + Y + + F I G ++ LD +++ ++ Sbjct: 301 LRVRAIDGDRGINNPIAYSLEANDL---FDINPHTG--IVHTLTKLDREEQSDQVNGAHI 355 Query: 439 LTVSATDSGGRSDTAM--------VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 L +SAT+ +S+T M V + ++D N+ P F Y V E+A T + Sbjct: 356 LRISATELS-KSNTQMAPTTVRTEVTVIVSDVNDEIPTFGETVYRCEVNENAQTNTPLNF 414 Query: 491 VSAT------DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA--ITTNKLLDRE 542 + D D G N T+ L + N+ + + +N + +K LD E Sbjct: 415 IDEEVQNVVFDHDEGNNG--TFRLFLDPPND-LFEIVPELAVNEANFMLRVKNSKSLDFE 471 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 + T+ AR+ PS + V+I + D NDN P F Q +Y A+++E++ T ++ Sbjct: 472 QFTEVNFTIFAREVDEPSRWSSAHVQIFIRDQNDNFPEFSQTIYNASVLENSEQDTIITH 531 Query: 603 VGATDADVGLNGR--IHYELDPKDREEGSFVIDPASGVIRTNK----ALDRESVATHDLK 656 V A D D G G I Y + + ++P +GVI + A DRE ++ H L Sbjct: 532 VQAVDVDSGDYGTMGIRY-TNLRGGIAHLLNLNPITGVITIKQAGGTAFDREIISRHYLT 590 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 AID +T + + I D+ND+ P F + EN T ++ A D D Sbjct: 591 VEAIDNAGQGNRNTAQIIVDILDVNDNAPTFPQRQYETKLLENQAEFETPLQLEARDADL 650 Query: 717 G--PNAVVHYSIKGGDDSNSFSLETRQG-------SDKAELV---TMVDLDYESPR---K 761 N+ V Y I G ++F+++ + G D ELV + Y + Sbjct: 651 NGTENSQVTYEIVEGLYRSNFTIDPQSGLLRPVHSFDFEELVDGSSRRSDPYTGGSFSIR 710 Query: 762 KYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVP 817 + +L++RA P L V V I V DVNDNAP+ + + P G +V Sbjct: 711 EIDLLVRARDSGIPMLSTVVPVLIYVQDVNDNAPIFQQ-SFYAKTVPEDLPGGSSVLQVT 769 Query: 818 AYDAD---VTDKLQYRILSGNNANLILLNET-----TGSMTLSPQLNTNVPKLATMEV 867 A D D + + YRI +G I+ +ET L P L + L T+ V Sbjct: 770 AIDRDGSAPNNVVVYRIQTGAGDKFIINSETGVISVAHGANLDPDLTESKRSLYTLSV 827 Score = 152 bits (369), Expect = 1e-34 Identities = 175/737 (23%), Positives = 312/737 (42%), Gaps = 85/737 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I VLD ND++P F + Y S+ E + +G ++ + A+D D KN + Y +E Sbjct: 989 IQVLDENDNNPKFRLPFYRQSITENSINGAMIVNVLASDVD--KNRTITYALEG------ 1040 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 NP + + +D ++G ++ + +D E+ V+ATD P Sbjct: 1041 NP------------TYRSLMHLDPQTGEIVVASKIDHEQHQWLNFSVRATDSGIPAR--- 1085 Query: 131 SSTATIHVNIIDDNDNYPQF--SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 SS +++ ++D+NDN P F K YT+S + +A ++A DAD G I Sbjct: 1086 SSLVDVYITVLDENDNNPYFVGGSKNYTISEN----AAPGTRVATLQAGDADSGDFGKIT 1141 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG------GSPSRSNTTQ 242 + + ++Q +F+ID+ +G +++ LD E SY LVI A D SR+ Q Sbjct: 1142 FLMDRISSQGKFTIDADTGVLTVADRLDRESKDSYNLVIEAWDNYQFGFLAGESRNAFKQ 1201 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV--NAELTYTMTDKD 300 + I+I D NDN P + ++E + + + DAD+ N L + +T + Sbjct: 1202 VFISILDENDNPPEVDLPMSCVLITEYHELHERVASIVGKDADDPTTPNGRLDFAITRGN 1261 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 G +L ID + ++ S L R Y L +T D G P T Sbjct: 1262 KDGMFELR-QIDAWNAQIFASKSL-RNRYGNYSLTITTRDMGLPANIVHNTLDICVSDFN 1319 Query: 361 XXXXXFMPGQYE--VELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITS 416 F+ + V + E+ GT ++ A+D D ++ + Y + + G + + Sbjct: 1320 DHAPVFVRPLHNTTVRIPENATVGTLILQAYASDGDMGQNALVRYRLKP-DPLGSYKMFE 1378 Query: 417 QNGR-GLITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENA 472 +G G + + + L+ ++++ + + + A D G S + I + + N+Y P F Sbjct: 1379 VDGSTGELFLKEQLNREKQKIHEIRIEAYDQGLPTSLSSDLDLTIYVRNVNDYEPQFMVN 1438 Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ-QFVINPQTG 531 + + E + G+ + + T + S++ V ++ F ++P+T Sbjct: 1439 EISVNFTEHSDPGSERIKLPDTIDKDQLELDDPNDTPSQVCYFIVNGNEAGYFRLDPETH 1498 Query: 532 AITTNKLLDRETMSGYLLTVTARDG-GVPSLSDTTDVEISVVDVND--NEPVFKQQL-YT 587 +T ++ LDRE ++ + L V A + S+S +++N+ V QQ Y Sbjct: 1499 ILTVDRELDREVIANFTLYVRATENCRNDSISGGEKRRRMGIEINNRLGGIVHNQQFGYD 1558 Query: 588 ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647 L T ++ G DA++ + YE +E DP G+ T+ LD Sbjct: 1559 RFKHSRQLRSTESNEYGPEDAEL-----LSYEAYDSSQE------DPTGGLATTHPELD- 1606 Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 S+ + V +++ DIND+PP F S T I+ N+ G Sbjct: 1607 --------------------STVIKVKVRVLDINDNPPRFRSKIFTGGITTNADFGLKFM 1646 Query: 708 EIRAHDPDEGPNAVVHY 724 + A D DEG N + Y Sbjct: 1647 RVEATDADEGDNGRIGY 1663 Score = 134 bits (325), Expect = 3e-29 Identities = 142/535 (26%), Positives = 226/535 (42%), Gaps = 48/535 (8%) Query: 373 VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRF---------------SITSQ 417 +++ E+ P GT V + ATD D L Y++ + GR + Sbjct: 886 LQILENTPVGTLVYRIQATDLDHKAILRYKLNPEHCEGRTEEGALVKSSEYDFLGAFEVD 945 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATD----SGGRSDTAMVQINITDANNYAPVFENAP 473 + G + V + LD ++ L ++ D G + + I + D N+ P F Sbjct: 946 SIEGTLKVVKLLDRERVEHIKLAITVEDLAAAKGRQIAEGFLSIQVLDENDNNPKFRLPF 1005 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 Y S+ E++ G ++V+ SDV N ITY+L + ++ H D PQTG I Sbjct: 1006 YRQSITENSINGA--MIVNVLASDVDKNRTITYALEGNPTYRSLMHLD------PQTGEI 1057 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593 +D E +V A D G+P+ S DV I+V+D NDN P F I E+ Sbjct: 1058 VVASKIDHEQHQWLNFSVRATDSGIPARSSLVDVYITVLDENDNNPYFVGGSKNYTISEN 1117 Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653 A GT V+ + A DAD G G+I + +D + +G F ID +GV+ LDRES ++ Sbjct: 1118 AAPGTRVATLQAGDADSGDFGKITFLMD-RISSQGKFTIDADTGVLTVADRLDRESKDSY 1176 Query: 654 DLKAVAID----GGTPPQSSTVI--VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 +L A D G +S V I I D ND+PP + I+E + + Sbjct: 1177 NLVIEAWDNYQFGFLAGESRNAFKQVFISILDENDNPPEVDLPMSCVLITEYHELHERVA 1236 Query: 708 EIRAHDPDE--GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765 I D D+ PN + ++I G+ F E RQ D + Y L Sbjct: 1237 SIVGKDADDPTTPNGRLDFAITRGNKDGMF--ELRQ-IDAWNAQIFASKSLRNRYGNYSL 1293 Query: 766 VIRAASPPLWNDV---RVEILVTDVNDNAPV-MKDFQIIFNNYKDCFPVGP-FGRVPAYD 820 I L ++ ++I V+D ND+APV ++ + VG + A D Sbjct: 1294 TITTRDMGLPANIVHNTLDICVSDFNDHAPVFVRPLHNTTVRIPENATVGTLILQAYASD 1353 Query: 821 ADVTDK--LQYRILSG--NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 D+ ++YR+ + + ++ +TG + L QLN K+ + + D Sbjct: 1354 GDMGQNALVRYRLKPDPLGSYKMFEVDGSTGELFLKEQLNREKQKIHEIRIEAYD 1408 Score = 122 bits (295), Expect = 1e-25 Identities = 144/523 (27%), Positives = 216/523 (41%), Gaps = 56/523 (10%) Query: 369 GQYEVELAEDEPPGTPVVTL--TATDADEDNR-LHYEITGGNTRGRFSITSQNGR-GLIT 424 GQ E+ L E P T V TL T D DN L + + I + G I Sbjct: 65 GQSEIVLRLKESPETKVGTLIYTLKGYDPDNDPLTFGKRNSHDSEIIRIENTGGNEAKIF 124 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ---INITDANNYAPVFENAPYTASVFED 481 +A+ LD + + Y + ++ TDS + Q + + D N+ P F PY ++ + Sbjct: 125 LAKELDRELQDEYAIVLTLTDSHYSDHNYVTQSFLLLVEDINDNVPTF--LPYQNAI--E 180 Query: 482 APIGTTVLVVS---ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 P G+ VVS ATD+D G Q+ Y L + V + G + K Sbjct: 181 IPEGSAPGVVSTLEATDADEGAYGQVVYYLQELDGDNDVF----SIATHQGKGILRLQKE 236 Query: 539 LDRETMSGYLLTVTARDGGV--PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 LD E S Y L V A D P + T + + V D+ D P F + A I EDA V Sbjct: 237 LDYERKSLYQLRVLAIDRANQGPINTGTAAILVKVKDLEDQPPEFVEVQAVARIAEDAPV 296 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA----- 651 GT V +V A D D G+N I Y L+ D F I+P +G++ T LDRE + Sbjct: 297 GTKVLRVRAIDGDRGINNPIAYSLEANDL----FDINPHTGIVHTLTKLDREEQSDQVNG 352 Query: 652 THDLKAVAID---GGTPPQSSTVIVHIKI--EDINDSPPVFESDCLTFYISENSPIGTTI 706 H L+ A + T +TV + + D+ND P F ++EN+ T + Sbjct: 353 AHILRISATELSKSNTQMAPTTVRTEVTVIVSDVNDEIPTFGETVYRCEVNENAQTNTPL 412 Query: 707 G----EIR--AHDPDEGPNAVVHYSIKGGDDSNSF--SLETRQGSDKAELVTMVDLDYES 758 E++ D DEG N + +D L + + + LD+E Sbjct: 413 NFIDEEVQNVVFDHDEGNNGTFRLFLDPPNDLFEIVPELAVNEANFMLRVKNSKSLDFEQ 472 Query: 759 -PRKKYELVIRAASPPL-WNDVRVEILVTDVNDNAP----VMKDFQIIFNNYKDCFPVGP 812 + + R P W+ V+I + D NDN P + + ++ N+ +D Sbjct: 473 FTEVNFTIFAREVDEPSRWSSAHVQIFIRDQNDNFPEFSQTIYNASVLENSEQDTI---- 528 Query: 813 FGRVPAYDADVTD----KLQYRILSGNNANLILLNETTGSMTL 851 V A D D D ++Y L G A+L+ LN TG +T+ Sbjct: 529 ITHVQAVDVDSGDYGTMGIRYTNLRGGIAHLLNLNPITGVITI 571 Score = 52.4 bits (120), Expect = 2e-04 Identities = 31/110 (28%), Positives = 51/110 (46%), Gaps = 7/110 (6%) Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY--- 294 S ++ + + D+NDN PRF + +F ++ N G +RV+A DADEG N + Y Sbjct: 1607 STVIKVKVRVLDINDNPPRFRSKIFTGGITTNADFGLKFMRVEATDADEGDNGRIGYYQV 1666 Query: 295 ---TMTDKDYTGNV-DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD 340 T + NV P +D +G V + + + + +V A D Sbjct: 1667 GEIRQTLSEGLENVRKAPFLLDQETGEVQLNFDPQKGMKGYFDFVVLAND 1716 Score = 42.7 bits (96), Expect = 0.14 Identities = 31/111 (27%), Positives = 52/111 (46%), Gaps = 6/111 (5%) Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509 S V++ + D N+ P F + +T + +A G + V ATD+D G N +I Y Sbjct: 1607 STVIKVKVRVLDINDNPPRFRSKIFTGGITTNADFGLKFMRVEATDADEGDNGRIGYYQV 1666 Query: 510 SEIS---NEAVAH-HDQQFVINPQTGAITTNKLLDRETMSGYL-LTVTARD 555 EI +E + + F+++ +TG + N ++ M GY V A D Sbjct: 1667 GEIRQTLSEGLENVRKAPFLLDQETGEVQLN-FDPQKGMKGYFDFVVLAND 1716 Score = 39.1 bits (87), Expect = 1.7 Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 6/65 (9%) Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYT--VSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 S+ + V ++D NDN P+F K +T ++ + D + +++ATDAD G N I Sbjct: 1607 STVIKVKVRVLDINDNPPRFRSKIFTGGITTNADFGLK----FMRVEATDADEGDNGRIG 1662 Query: 189 YAIIG 193 Y +G Sbjct: 1663 YYQVG 1667 Score = 37.9 bits (84), Expect = 4.0 Identities = 17/54 (31%), Positives = 27/54 (50%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEY 60 I ++ VLD ND+ P F + + + A G + ++ATD D G N + Y Sbjct: 1610 IKVKVRVLDINDNPPRFRSKIFTGGITTNADFGLKFMRVEATDADEGDNGRIGY 1663 >UniRef50_Q9H158 Cluster: Protocadherin alpha C1 precursor; n=12; Amniota|Rep: Protocadherin alpha C1 precursor - Homo sapiens (Human) Length = 963 Score = 213 bits (519), Expect = 8e-53 Identities = 174/640 (27%), Positives = 290/640 (45%), Gaps = 38/640 (5%) Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV-RSYRLVIRAQDGGSPSRSNTT 241 A S+ + + + ++ F +D SG++ + + D EQ+ R+ + D Sbjct: 49 AMSSRNFRFLSSHRELYFGVDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELH 108 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 ++ I++ D NDN+P F Q + E + G A D DEG N L+Y+++ + Sbjct: 109 KIRIHVLDTNDNSPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQH 168 Query: 302 TGNVDLPITIDPRS-GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 +D+ +D + LDRE +A + L++TA DGG P RS A Sbjct: 169 F-RLDMGSRVDGSEYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTN 227 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI---TGGNTRGRFSIT 415 F Y ++ E P GT + + A D DE + + Y + T R RF + Sbjct: 228 DNAPVFERSVYRTKVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVH 287 Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAP 473 ++G + VA L E + A D G G + TA + + +TD N++AP + Sbjct: 288 PKSGE--VQVAASLG-PPETLLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLT 344 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 + V EDA GT + + S D D+ N ++ +SS + A D + ++ Sbjct: 345 LSNPVPEDAAPGTVIALFSVKDEDLDSNGRVICGMSSAGPFQLTASFDNYY-------SL 397 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593 + LDRE +S Y + +TA D G P LS + +SV DVNDN P F Q + E+ Sbjct: 398 LIDGPLDREQISEYQVLITASDSGSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAEN 457 Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS----FVIDPASGVIRTNKALDRES 649 G S+ +V A D D+G NG + YEL E S ++ +SG I + D E Sbjct: 458 NGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPSASSLLAVESSSGAITAKTSFDFEQ 517 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF------ESDCLTFYISENSPIG 703 + + DGG PP+S+TV +++ + D ND+ PV + ++ G Sbjct: 518 LRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTG 577 Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK-AELVTMVDLDYESPRKK 762 + ++ A D D G NA + Y I DS+ F + G + A LV L ++ +++ Sbjct: 578 HLVTKVVAEDADSGSNAWLSYHISRASDSSLFRISANIGELRTARLV----LPTDAVKQR 633 Query: 763 YELVIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801 +V+R PPL + V + +L++ N ++ DF+ ++ Sbjct: 634 VVVVVRDHGDPPLSSSVTLGVLLS--NSVPQLLPDFEDVW 671 Score = 204 bits (498), Expect = 3e-50 Identities = 170/603 (28%), Positives = 264/603 (43%), Gaps = 23/603 (3%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F +D SG L+ R DRE++ R T + D L I ++++D NDN P Sbjct: 66 FGVDLPSGNLVVREPADREQLCRAKAACVLTYDLV-LEDPLE-LHKIRIHVLDTNDNSPL 123 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN---TQMQFSID-SL 205 F + + E + T A D D G+N + Y++ M +D S Sbjct: 124 FPAGDVQLHIPEFL--TPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSE 181 Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265 ++ L K LD EQ ++ LV+ A+DGG P+RS Q+ I + D NDNAP F S+++ Sbjct: 182 YPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTK 241 Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325 V E P G + RVQA D DEG N E+ Y++++ + + P+SG V + L Sbjct: 242 VPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNST-QAELRHRFHVHPKSGEVQVAASLG 300 Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 + + + A D G ++TA + ED PGT + Sbjct: 301 -PPETLLEAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVI 359 Query: 386 VTLTATDADEDNRLHYEITGGNTRGRFSIT-SQNGRGLITVAQPLDFKQERRYVLTVSAT 444 + D D D+ I G ++ G F +T S + + + PLD +Q Y + ++A+ Sbjct: 360 ALFSVKDEDLDSNGRV-ICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITAS 418 Query: 445 DSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502 DSG S + +++ D N+ P F V E+ G ++ V A D D+G N Sbjct: 419 DSGSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNG 478 Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 ++Y L IS A + +GAIT D E + G+ V RDGG+P S Sbjct: 479 LVSYELLDVISEGPSA--SSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRS 536 Query: 563 DTTDVEISVVDVNDNEPVF------KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616 T + + VVD NDN PV + + A G V++V A DAD G N + Sbjct: 537 ATVTINLFVVDRNDNYPVILFPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWL 596 Query: 617 HYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676 Y + + + F I G +RT + + + V D G PP SS+V + + Sbjct: 597 SYHIS-RASDSSLFRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVL 655 Query: 677 IED 679 + + Sbjct: 656 LSN 658 Score = 165 bits (402), Expect = 1e-38 Identities = 157/585 (26%), Positives = 248/585 (42%), Gaps = 53/585 (9%) Query: 4 PFCIHQ-QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 P +H+ +I+VLD ND+SP+F + + E + G A D D G N + Y Sbjct: 104 PLELHKIRIHVLDTNDNSPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSY-- 161 Query: 63 ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRS-GALLTRASLDREKVARYTVLVKATD 121 +L+P R+DG L+ +LDRE+ A + +++ A D Sbjct: 162 ------SLSPSQHFRLDMGS--------RVDGSEYPELVLEKALDREQRATHLLVLTARD 207 Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181 P S A + + ++D NDN P F Y V E + + V+ +++A D D Sbjct: 208 GGLPAR---SGDAQVTIIVVDTNDNAPVFERSVYRTKVPE--TAPNGTVLFRVQALDPDE 262 Query: 182 GANSAIRYAIIGGNTQMQ----FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237 G+N ++Y+ + +TQ + F + SG+V + +L + I A+D G Sbjct: 263 GSNGEVQYS-LSNSTQAELRHRFHVHPKSGEVQVAASLGPPET-LLEAYIEARDEGVFGL 320 Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297 ++T +LL+ + DVND+AP V E+ G I D D N + M+ Sbjct: 321 ASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKDEDLDSNGRVICGMS 380 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357 G L + D + G LDRE ++YQ+L+TA+D G PP S T Sbjct: 381 S---AGPFQLTASFDNYYS-LLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITVSVA 436 Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFS-- 413 F Q E+ +AE+ PG + + A D D ++ + YE+ + G + Sbjct: 437 DVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPSASS 496 Query: 414 -ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDAN-NYAPVF 469 + ++ G IT DF+Q R + V D G RS T + + + D N NY + Sbjct: 497 LLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYPVIL 556 Query: 470 ENAPYTASV-FEDAP----IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524 P SV E P G V V A D+D G NA ++Y +S A F Sbjct: 557 FPLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISR-------ASDSSLF 609 Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569 I+ G + T +L+ + V RD G P LS + + + Sbjct: 610 RISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGV 654 Score = 137 bits (331), Expect = 5e-30 Identities = 119/408 (29%), Positives = 187/408 (45%), Gaps = 21/408 (5%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 ++I++ D N+ +P+F + E G + +A D D G N ++YSLS + Sbjct: 110 IRIHVLDTNDNSPLFPAGDVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSP---S 166 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 + V + + K LDRE + +LL +TARDGG+P+ S V I VVD Sbjct: 167 QHFRLDMGSRVDGSEYPELVLEKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDT 226 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE--GSFVI 632 NDN PVF++ +Y + E A GT + +V A D D G NG + Y L + E F + Sbjct: 227 NDNAPVFERSVYRTKVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHV 286 Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692 P SG ++ +L + A D G +ST + +++ D+ND P + L Sbjct: 287 HPKSGEVQVAASLGPPETLL-EAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTL 345 Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752 + + E++ GT I D D N V I G + F L T + L+ Sbjct: 346 SNPVPEDAAPGTVIALFSVKDEDLDSNGRV---ICGMSSAGPFQL-TASFDNYYSLLIDG 401 Query: 753 DLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809 LD E +Y+++I A+ SPPL + + V DVNDN P Q ++ P Sbjct: 402 PLDREQ-ISEYQVLITASDSGSPPLSTRRTITVSVADVNDNTPNFPQPQQELFVAENNGP 460 Query: 810 VGPFGRVPAYDADV--TDKLQYRIL----SGNNA-NLILLNETTGSMT 850 GRV A D D+ + Y +L G +A +L+ + ++G++T Sbjct: 461 GASLGRVFAQDPDLGKNGLVSYELLDVISEGPSASSLLAVESSSGAIT 508 Score = 135 bits (326), Expect = 2e-29 Identities = 128/465 (27%), Positives = 197/465 (42%), Gaps = 37/465 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V+D ND++PVFE Y V E A +GT + ++A D D G N EV+Y++ T L Sbjct: 221 IIVVDTNDNAPVFERSVYRTKVPETAPNGTVLFRVQALDPDEGSNGEVQYSLSNSTQAEL 280 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 F + +SG + ASL + ++A D+ L Sbjct: 281 RHR----------------FHVHPKSGEVQVAASLGPPETL-LEAYIEARDEG---VFGL 320 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +STA + V + D ND+ P+ T + V ED VIA D D+ +N + Sbjct: 321 ASTAKLLVEVTDVNDHAPELDFLTLSNPVPED--AAPGTVIALFSVKDEDLDSNGRVICG 378 Query: 191 I-IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 + G Q+ S D+ + + LD EQ+ Y+++I A D GSP S + +++ D Sbjct: 379 MSSAGPFQLTASFDNYY-SLLIDGPLDREQISEYQVLITASDSGSPPLSTRRTITVSVAD 437 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NVDLP 308 VNDN P F + V+EN G S+ RV A D D G N ++Y + D G + Sbjct: 438 VNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLDVISEGPSASSL 497 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM- 367 + ++ SG + D E + V DGG PPRSAT T + Sbjct: 498 LAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVVDRNDNYPVILF 557 Query: 368 ----PGQYEVELA-EDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGR 420 G VE+ G V + A DAD + L Y I+ + F I++ G Sbjct: 558 PLPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASDSSLFRISANIGE 617 Query: 421 -GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANN 464 + P D ++R + V D G ++ V + + +N+ Sbjct: 618 LRTARLVLPTDAVKQR---VVVVVRDHGDPPLSSSVTLGVLLSNS 659 >UniRef50_UPI0000EB26D2 Cluster: UPI0000EB26D2 related cluster; n=1; Canis lupus familiaris|Rep: UPI0000EB26D2 UniRef100 entry - Canis familiaris Length = 599 Score = 212 bits (518), Expect = 1e-52 Identities = 169/524 (32%), Positives = 248/524 (47%), Gaps = 38/524 (7%) Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 D F + +G + T LDRE+ RY AT L + + + + D ND+ Sbjct: 95 DDFHVHADTGIIRTARRLDRERRDRYG-FAAAT--------LLGAVVQVEIRVNDVNDHS 145 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 P+F + + V E +S V A D D G Y ++ Q+++ S Sbjct: 146 PRFPRDSLRLDVSE-LSPPGTAVRLP-GAHDPDAGLFGTQGYTLL--LFQLRYGTPGSSP 201 Query: 208 ----DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263 D+ L++ LD E ++ L I A DGG P R+ ++ + + D NDN P F ++ Sbjct: 202 PEPLDLVLLRRLDREAAAAHELHIEAWDGGRPPRTGHLRVELRVLDENDNPPVFERGEYR 261 Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323 +V E+ P G + RV+A D D G N + Y++ + P ++ SG V Sbjct: 262 AAVREDAPPGAEVCRVRATDRDLGRNGLVRYSLRARQ------APFAVEELSGVVRVRRP 315 Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX----XXXXXFMPGQYEVELAEDE 379 LDRE QA +QLLV A DGG PP AT + ++E Sbjct: 316 LDREAQAWHQLLVEARDGGAPPEVATVRLSVAVLDVNDNPPAIHLLLLTDGGAARVSEGA 375 Query: 380 PPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL--ITVAQPLDFKQERRY 437 PG V ++ +DAD D ++ G F++ + G+ + VA PLD + Y Sbjct: 376 APGDYVARVSVSDADGDPEPRDSLSLEGGEGAFALRAGGSPGVFFLCVAGPLDREARDLY 435 Query: 438 VLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495 L + ATD+G +A + + + D N+ PVF Y SV E A GT VL VSATD Sbjct: 436 DLRLVATDAGSPPLSAEETLLLRVADLNDRPPVFGRERYVGSVSEAAAPGTAVLRVSATD 495 Query: 496 SD-VGIN-AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553 +D G + A++ Y+L A A F I+P++G I+T++ LDRE L V A Sbjct: 496 ADEAGTDHARLRYALVHLPGRCAPA-----FAIDPESGVISTSRSLDREVQEAVELRVVA 550 Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 +D G P LS T V I+V DVNDNEPVF++Q+Y A + E A VG Sbjct: 551 QDLGAPPLSATCLVSITVDDVNDNEPVFRRQVYNATLAEHAPVG 594 Score = 198 bits (483), Expect = 2e-48 Identities = 152/473 (32%), Positives = 227/473 (47%), Gaps = 22/473 (4%) Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 Q+ I + DVND++PRF + VSE P G ++ A+D D G+ YT+ + Sbjct: 133 QVEIRVNDVNDHSPRFPRDSLRLDVSELSPPGTAVRLPGAHDPDAGLFGTQGYTLLL--F 190 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 P + P + +LDRE A ++L + A DGG PPR+ Sbjct: 191 QLRYGTPGSSPPEPLDLVLLRRLDREAAAAHELHIEAWDGGRPPRTGHLRVELRVLDEND 250 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419 F G+Y + ED PPG V + ATD D + + Y + + F++ +G Sbjct: 251 NPPVFERGEYRAAVREDAPPGAEVCRVRATDRDLGRNGLVRYSLRA--RQAPFAVEELSG 308 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYT-- 475 ++ V +PLD + + + L V A D G + A V++++ D N+ P T Sbjct: 309 --VVRVRRPLDREAQAWHQLLVEARDGGAPPEVATVRLSVAVLDVNDNPPAIHLLLLTDG 366 Query: 476 --ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 A V E A G V VS +D+D + + SLS E A A +P + Sbjct: 367 GAARVSEGAAPGDYVARVSVSDADG--DPEPRDSLSLEGGEGAFALRAGG---SPGVFFL 421 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593 LDRE Y L + A D G P LS + + V D+ND PVF ++ Y ++ E Sbjct: 422 CVAGPLDREARDLYDLRLVATDAGSPPLSAEETLLLRVADLNDRPPVFGRERYVGSVSEA 481 Query: 594 ALVGTSVSQVGATDAD-VGLN-GRIHYEL-DPKDREEGSFVIDPASGVIRTNKALDRESV 650 A GT+V +V ATDAD G + R+ Y L R +F IDP SGVI T+++LDRE Sbjct: 482 AAPGTAVLRVSATDADEAGTDHARLRYALVHLPGRCAPAFAIDPESGVISTSRSLDREVQ 541 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703 +L+ VA D G PP S+T +V I ++D+ND+ PVF ++E++P+G Sbjct: 542 EAVELRVVAQDLGAPPLSATCLVSITVDDVNDNEPVFRRQVYNATLAEHAPVG 594 Score = 163 bits (395), Expect = 8e-38 Identities = 151/516 (29%), Positives = 228/516 (44%), Gaps = 43/516 (8%) Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374 +G + T+ +LDRE + +Y G A F ++ Sbjct: 103 TGIIRTARRLDRERRDRYGFAAATLLG------AVVQVEIRVNDVNDHSPRFPRDSLRLD 156 Query: 375 LAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432 ++E PPGT V A D D Y + R +S + + + LD + Sbjct: 157 VSELSPPGTAVRLPGAHDPDAGLFGTQGYTLLLFQLRYGTPGSSPPEPLDLVLLRRLDRE 216 Query: 433 QERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 + L + A D G R+ V++ + D N+ PVFE Y A+V EDAP G V Sbjct: 217 AAAAHELHIEAWDGGRPPRTGHLRVELRVLDENDNPPVFERGEYRAAVREDAPPGAEVCR 276 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550 V ATD D+G N + YSL + F + +G + + LDRE + + L Sbjct: 277 VRATDRDLGRNGLVRYSLRAR---------QAPFAVEELSGVVRVRRPLDREAQAWHQLL 327 Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT----ANIMEDALVGTSVSQVGAT 606 V ARDGG P T + ++V+DVNDN P L T A + E A G V++V + Sbjct: 328 VEARDGGAPPEVATVRLSVAVLDVNDNPPAIHLLLLTDGGAARVSEGAAPGDYVARVSVS 387 Query: 607 DADVGLNGRIHYELDPKDREEGSFVI----DPASGVIRTNKALDRESVATHDLKAVAIDG 662 DAD R L+ EG+F + P + LDRE+ +DL+ VA D Sbjct: 388 DADGDPEPRDSLSLEGG---EGAFALRAGGSPGVFFLCVAGPLDREARDLYDLRLVATDA 444 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG--PNA 720 G+PP S+ + +++ D+ND PPVF + +SE + GT + + A D DE +A Sbjct: 445 GSPPLSAEETLLLRVADLNDRPPVFGRERYVGSVSEAAAPGTAVLRVSATDADEAGTDHA 504 Query: 721 VVHYSI--KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLW 775 + Y++ G + +F+++ G + T LD E ++ EL + A +PPL Sbjct: 505 RLRYALVHLPGRCAPAFAIDPESG----VISTSRSLDRE-VQEAVELRVVAQDLGAPPLS 559 Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811 V I V DVNDN PV + Q+ + PVG Sbjct: 560 ATCLVSITVDDVNDNEPVFRR-QVYNATLAEHAPVG 594 Score = 147 bits (355), Expect = 6e-33 Identities = 120/379 (31%), Positives = 164/379 (43%), Gaps = 32/379 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ VLD ND+ PVFE +Y A+VRE A G V ++ATD+D+G+N V Y++ Sbjct: 242 ELRVLDENDNPPVFERGEYRAAVREDAPPGAEVCRVRATDRDLGRNGLVRYSLR------ 295 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 Q F ++ SG + R LDRE A + +LV+A D +P Sbjct: 296 ---------------ARQAPFAVEELSGVVRVRRPLDREAQAWHQLLVEARDGGAPPE-- 338 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP--VIAKIKATDADVGANSAI 187 +T + V ++D NDN P T +S P +A++ +DAD Sbjct: 339 -VATVRLSVAVLDVNDNPPAIHLLLLTDGGAARVSEGAAPGDYVARVSVSDADGDPEPRD 397 Query: 188 RYAIIGGNTQMQFSIDSLSG--DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 ++ GG G + + LD E Y L + A D GSP S LL+ Sbjct: 398 SLSLEGGEGAFALRAGGSPGVFFLCVAGPLDREARDLYDLRLVATDAGSPPLSAEETLLL 457 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG--VNAELTYTMTDKDYTG 303 + D+ND P F + SVSE G +++RV A DADE +A L Y + G Sbjct: 458 RVADLNDRPPVFGRERYVGSVSEAAAPGTAVLRVSATDADEAGTDHARLRYALV--HLPG 515 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 IDP SG + TS LDRE Q +L V A D G PP SAT Sbjct: 516 RCAPAFAIDPESGVISTSRSLDREVQEAVELRVVAQDLGAPPLSATCLVSITVDDVNDNE 575 Query: 364 XXFMPGQYEVELAEDEPPG 382 F Y LAE P G Sbjct: 576 PVFRRQVYNATLAEHAPVG 594 Score = 121 bits (291), Expect = 3e-25 Identities = 92/277 (33%), Positives = 135/277 (48%), Gaps = 21/277 (7%) Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583 F ++ TG I T + LDRE Y G V VEI V DVND+ P F + Sbjct: 97 FHVHADTGIIRTARRLDRERRDRYGFAAATLLGAV------VQVEIRVNDVNDHSPRFPR 150 Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL---DPKDREEGSFVIDPASGVIR 640 ++ E + GT+V GA D D GL G Y L + GS +P V+ Sbjct: 151 DSLRLDVSELSPPGTAVRLPGAHDPDAGLFGTQGYTLLLFQLRYGTPGSSPPEPLDLVLL 210 Query: 641 TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700 + LDRE+ A H+L A DGG PP++ + V +++ D ND+PPVFE + E++ Sbjct: 211 --RRLDREAAAAHELHIEAWDGGRPPRTGHLRVELRVLDENDNPPVFERGEYRAAVREDA 268 Query: 701 PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760 P G + +RA D D G N +V YS++ F++E G + LD E+ + Sbjct: 269 PPGAEVCRVRATDRDLGRNGLVRYSLRA--RQAPFAVEELSGVVRVRR----PLDREA-Q 321 Query: 761 KKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVM 794 ++L++ A +PP VR+ + V DVNDN P + Sbjct: 322 AWHQLLVEARDGGAPPEVATVRLSVAVLDVNDNPPAI 358 Score = 96.3 bits (229), Expect = 1e-17 Identities = 83/280 (29%), Positives = 127/280 (45%), Gaps = 30/280 (10%) Query: 7 IHQQINVLDCNDHSPVFEMQQYE----ASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 + + VLD ND+ P + A V EGA+ G V + +D D + E Sbjct: 342 VRLSVAVLDVNDNPPAIHLLLLTDGGAARVSEGAAPGDYVARVSVSDAD----GDPE--- 394 Query: 63 ELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ 122 D+L+ E VF L LDRE Y + + ATD Sbjct: 395 ---PRDSLSLEGGEGAFALRAGGSPGVF-------FLCVAGPLDREARDLYDLRLVATDA 444 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD-V 181 SP LS+ T+ + + D ND P F + Y SV E + + ++ ATDAD Sbjct: 445 GSPP---LSAEETLLLRVADLNDRPPVFGRERYVGSVSE--AAAPGTAVLRVSATDADEA 499 Query: 182 GANSA-IRYAIIG--GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238 G + A +RYA++ G F+ID SG +S ++LD E + L + AQD G+P S Sbjct: 500 GTDHARLRYALVHLPGRCAPAFAIDPESGVISTSRSLDREVQEAVELRVVAQDLGAPPLS 559 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR 278 T + I + DVNDN P F ++ +++E+ P+G+ ++ Sbjct: 560 ATCLVSITVDDVNDNEPVFRRQVYNATLAEHAPVGHCFLQ 599 >UniRef50_Q5CCS8 Cluster: Fc1-cadherin; n=2; Hexapoda|Rep: Fc1-cadherin - Folsomia candida Length = 1565 Score = 212 bits (517), Expect = 1e-52 Identities = 195/722 (27%), Positives = 320/722 (44%), Gaps = 64/722 (8%) Query: 17 NDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAX 76 ++++P + +Y+ S+ + + G V+ + ATD D G N V Y E NP D Sbjct: 231 HEYNPHLDKYEYKESMPQDLALGQVVMRISATDIDDGNNGTVVYACE---PHPQNPNDV- 286 Query: 77 XXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATI 136 + F I SG + + + ++ ++ + + A+D P + ++ + + Sbjct: 287 -----------EFFDISSASGEITLKKRIGNQQ--KFQLRIVASDLGVPPNSAITDLSIV 333 Query: 137 HVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNT 196 + + + P+F + +DE I PV ++AD + + + ++ G T Sbjct: 334 ---VAEPSQRPPEFINPPTLIHLDEYIYNLSVPVATLSARSNAD---DELVFFELVNGQT 387 Query: 197 QMQ-----FSIDSL---SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Q F++++ + + L + LDYE Y L IRAQ+ + + T L + + Sbjct: 388 QPTNKEAIFTLETEGRNTAHIKLDRQLDYESTTRYTLTIRAQN--KYNLAAETLLTVMVN 445 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYTMTDKDYTGNVDL 307 D ND P ++T + +V EN PIG S++RV+A D D N E+TY + D N Sbjct: 446 DKNDEKP-YFTEVTTGTVLENEPIGTSVMRVRAIDTDGTAPNNEVTYHLKS-DEEDN--- 500 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-------PRSATATXXXXXXXXX 360 +ID SG + T DRE + YQ++V A DG P T Sbjct: 501 -FSIDAISGEIKTRKMFDREEKDTYQVIVYAKDGAPSVKLNNGQPNERPQTLKIVIADKN 559 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR 420 F+ YE E++ED VV + A DAD + L Y IT GN F+I S + Sbjct: 560 DNGPVFVRDLYEAEMSEDADLNRVVVEVRAKDADTASVLQYTITEGNIDDAFAIRSTSTS 619 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 G+ITV LDF+ R+Y LTV +DS + T V+I I + N+ P FE ++ E Sbjct: 620 GVITVKNKLDFESIRQYELTVRVSDSVHEAKT-KVKIYIQNVNDEPPKFEPMNSNTTIVE 678 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 + + V A D D+G + + ++S I + F + P G + K LD Sbjct: 679 EFIPSDCIFRVKAYDPDIG-DRTVPQNISYFILT-----GKEHFSVGPDDGCVKVIKPLD 732 Query: 541 RETMSGYLLTVTARD--GGVPSLSD-TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 RE Y + V A D G P+ D ++ ++++D+NDN PV Q + + Sbjct: 733 REDKPFYQMVVGASDEWGLAPTKLDFYKELIVNLIDINDNAPVLSSQ--NPVVWNENQPR 790 Query: 598 TSVSQVGATDADVGLNG-RIHYELDPKDREEGSFVIDPASGVIRTNK-ALDRESVATHDL 655 ++Q+ ATDAD NG + +DPK + + ++ NK DRE V + + Sbjct: 791 GPITQLDATDADSPENGPPFTFSIDPKADMKIKELFSIEGKTLKANKDDFDREEVKQYVV 850 Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSP-PVFESDCLTFYISENSPIGTTIGEIRAHDP 714 D G ++ T + + I D ND+ ES + E +P IG + DP Sbjct: 851 PIAISDSGRERKTGTSYLTVIIGDQNDNDMQDGESRIFVYKYKERNPF--PIGRVYVKDP 908 Query: 715 DE 716 D+ Sbjct: 909 DD 910 Score = 210 bits (513), Expect = 4e-52 Identities = 331/1370 (24%), Positives = 547/1370 (39%), Gaps = 180/1370 (13%) Query: 17 NDHSPVF-EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDA 75 N H P F + Y S+ EG T V+ +KA DQD ++ T +V+ + + + Sbjct: 99 NLHKPDFVDCGSYRPSIPEGEPVDTPVIQVKALDQDPPESGGT-VTYSIVSGNEMLAD-- 155 Query: 76 XXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYT---VLVKATDQASPVSDRLSS 132 F +D +G + TR DR++ A+ V V+A+D +P RL + Sbjct: 156 --------------FAVDEHTGWISTRKIFDRDEPAKEKEVYVTVQASDNGNP---RLDA 198 Query: 133 TATIHVNIIDDNDNYPQF---------------------SEKTYTVSVDEDISVTDNPVI 171 T+ V I D NDN QF + Y S+ +D+++ V+ Sbjct: 199 VCTLKVKITDINDNTAQFLLSRRFNQGSYVPEHEYNPHLDKYEYKESMPQDLAL--GQVV 256 Query: 172 AKIKATDADVGANSAIRYAII----GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVI 227 +I ATD D G N + YA N F I S SG+++L K + +Q ++L I Sbjct: 257 MRISATDIDDGNNGTVVYACEPHPQNPNDVEFFDISSASGEITLKKRIGNQQ--KFQLRI 314 Query: 228 RAQDGGSPSRSNTTQLLINIRDVNDNAPRFY---TSLFQESVSENVPIGYSIVRVQAYDA 284 A D G P S T L I + + + P F T + + N+ + + + ++ Sbjct: 315 VASDLGVPPNSAITDLSIVVAEPSQRPPEFINPPTLIHLDEYIYNLSVPVATLSARSNAD 374 Query: 285 DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP 344 DE V EL T + T + + QLD E+ +Y L + A + + Sbjct: 375 DELVFFELVNGQTQPTNKEAIFTLETEGRNTAHIKLDRQLDYESTTRYTLTIRAQNKYN- 433 Query: 345 PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHY 401 A T + + E+EP GT V+ + A D D +N + Y Sbjct: 434 --LAAETLLTVMVNDKNDEKPYFTEVTTGTVLENEPIGTSVMRVRAIDTDGTAPNNEVTY 491 Query: 402 EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD-------SGGRSDTA- 453 + + FSI + +G I + D +++ Y + V A D + G+ + Sbjct: 492 HLKS-DEEDNFSIDAISGE--IKTRKMFDREEKDTYQVIVYAKDGAPSVKLNNGQPNERP 548 Query: 454 -MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512 ++I I D N+ PVF Y A + EDA + V+ V A D+D + + Y+++ Sbjct: 549 QTLKIVIADKNDNGPVFVRDLYEAEMSEDADLNRVVVEVRAKDADTA--SVLQYTITEGN 606 Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572 ++A A +G IT LD E++ Y LTV D + T V+I + Sbjct: 607 IDDAFAIRSTS-----TSGVITVKNKLDFESIRQYELTVRVSDSVHEA---KTKVKIYIQ 658 Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG---LNGRIHYELDPKDREEGS 629 +VND P F+ I+E+ + + +V A D D+G + I Y + +E Sbjct: 659 NVNDEPPKFEPMNSNTTIVEEFIPSDCIFRVKAYDPDIGDRTVPQNISYFI-LTGKEH-- 715 Query: 630 FVIDPASGVIRTNKALDRESVATHDLKAVAIDG-GTPPQSSTVIVHIKIE--DINDSPPV 686 F + P G ++ K LDRE + + A D G P + + DIND+ PV Sbjct: 716 FSVGPDDGCVKVIKPLDREDKPFYQMVVGASDEWGLAPTKLDFYKELIVNLIDINDNAPV 775 Query: 687 FESDCLTFYISENSPIG--TTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD 744 S + +EN P G T + A P+ GP +SI D L + +G Sbjct: 776 LSSQNPVVW-NENQPRGPITQLDATDADSPENGPPFT--FSIDPKADMKIKELFSIEG-- 830 Query: 745 KAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVE---ILVTDVNDNAPVMKDFQIIF 801 K D D E K+Y + I + +++ D NDN + +I Sbjct: 831 KTLKANKDDFDREEV-KQYVVPIAISDSGRERKTGTSYLTVIIGDQNDNDMQDGESRIFV 889 Query: 802 NNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPK 861 YK+ P P GRV D D D + + ++ TG + + + Sbjct: 890 YKYKERNPF-PIGRVYVKDPDDWDLPDKTFTLTTSNSHFTVDSDTGYINMKSTAEPS-DH 947 Query: 862 LATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSP--LLGFFIDG 919 + T +V + + + A + ++V+ IT+E + NS ++R T EQF+ G Sbjct: 948 VLTFKVEDSRWGSTVNAKVTVTVKEITDEAVDNSGSIRFMGTTKEQFIKVDRTTGLSKKD 1007 Query: 920 -----LAAIIPCPKENIYIFSVQDDTDVTG-NILNVSFSARRPDAEVGVAGDPSPHYSPT 973 LA I P EN+ +F+V + ++ N +V +S SP++ Sbjct: 1008 KLQRELARIFEVPIENVDVFTVGNSPSISDMNFFDVRYSVHN-----------SPYWKAE 1056 Query: 974 HLRERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLF 1033 L ++ + L + + ++ + C+ E C L + + ++ F Sbjct: 1057 KLNGKLAESKDLLEKHLELNIVMIGIDECLKEKHFCESSCSNTLAKSDIPLKIFTNETSF 1116 Query: 1034 RPIYPVTSFTCQCPEGFTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCS 1093 ++ + C C NC C +G IC SG GG+ C Sbjct: 1117 VGVHAIVQPVCNCSSFQPPNNC----LPNPCLNNG---ICTSG--------GGLDGFKCE 1161 Query: 1094 IDAAYTTAVCELRARSFPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRYNERH- 1152 DA + CE+ + + F FP L + L+++F + SGL+ YNG + Sbjct: 1162 CDAPFDGPRCEITSIALDGVGFAWFPSLTVCNDSSLQVEFMA-SKSGLIFYNGPIYQSSV 1220 Query: 1153 -DFLALELVSSEAGRGGGPGLRFSFSLGGGKSEITVEGNVGDGSWHTVEIEYFNRTITMI 1211 DF++LEL R G P L + G + EI + DG H V I + I+M Sbjct: 1221 TDFMSLEL------RDGKPMLLMDYGTGVSRLEIEHSPMLADGLSHKVHITWNPSAISMR 1274 Query: 1212 LDDCDKVLSLAGAADFGLKYACANFTRKVLPARCEIPTETCHRFLDLTGPLQIGGLPNIP 1271 +D+C K + C R PT T + L++ GP Q+GG+ P Sbjct: 1275 VDECRK-----------NEPTCYRTAR---------PTGT-NSQLNVNGPFQLGGISFDP 1313 Query: 1272 SSF-------QVKNKDFV-GCISDFYIDHKFIDLN--SYVADNGTLAGCP 1311 Q+ +K+F GCI++ + ++++L SY N T P Sbjct: 1314 KRLQNSMKWSQIPSKEFFQGCIANLTFNGEYVNLGNPSYSTLNVTTCDSP 1363 >UniRef50_UPI0000F1EDA6 Cluster: PREDICTED: hypothetical protein; n=2; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 970 Score = 211 bits (516), Expect = 2e-52 Identities = 167/605 (27%), Positives = 270/605 (44%), Gaps = 36/605 (5%) Query: 97 GALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT 156 G L +DRE++ + T + VS + V ++D NDN P+F T Sbjct: 82 GRLTAEERVDRERICKRNPRCVITFDVAFVSAEQFELFHVEVEVLDVNDNSPEFPRAECT 141 Query: 157 VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS-------GDV 209 V + E ++ IA A D+DVG+NS Y + + FSID ++ ++ Sbjct: 142 VEISESAALGTR--IALDAAEDSDVGSNSIQSYEL---SENSHFSIDVITRVDGVKYAEL 196 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269 LVK LD E + L + A DGG P RS +T + + ++D NDN+P F S + V E+ Sbjct: 197 VLVKELDREARAFFALKLVAADGGHPPRSGSTNVTVKVKDANDNSPLFDHSHYSVDVPED 256 Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329 P+ ++ + A D DEG+N ++ Y K T + +D ++G++ +D E + Sbjct: 257 TPVEALLLDLNAIDPDEGLNGQVVYEF-GKQVTTEIRQLFKLDYKTGYLTLQSPVDYEDE 315 Query: 330 AKYQLLVTATD-GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV-----ELAEDEPPGT 383 Y++ V ATD G +P S + V ++E P Sbjct: 316 TTYEIDVQATDLGHNPVPSVCKIIINIRDVNDNPPEIIITSITSVTDGVAHVSEATGPDI 375 Query: 384 PVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441 V ++ D D + ++ + GG+ R + ++T+A PLD ++ Y LTV Sbjct: 376 LVALISIKDKDTGANGQVSCTLNGGHGNFRLKRAYEGSYTIVTMA-PLDREKIAEYNLTV 434 Query: 442 SATDSGGRSDTAMVQ--INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499 A D G + Q + +TD N+ AP F Y + E+ GT + + A+D D G Sbjct: 435 VAEDFGVPPLRTVTQYIVRLTDVNDNAPAFSAKIYEGFIEENQLPGTYITTILASDQDSG 494 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 +N +ITY L +N +F I Q G + + + E L V A D G P Sbjct: 495 LNGEITYELFDSDTNSV-----SRFAIMNQAGNVYALQSFNYEVTKRLDLRVQASDRGWP 549 Query: 560 SLSDTTDVEISVVDVNDNEP-VFKQQLYTAN----IMEDALVGTSVSQVGATDADVGLNG 614 L + + I+VVD NDN P + L + + DA G V+++ A D+D GLN Sbjct: 550 QLHNNAILIINVVDQNDNTPFITHPPLINGSAEIQLPRDAPPGYIVTRIIAKDSDAGLNA 609 Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674 + Y++ D + F IDP +G I N+ + + + D G P Q+ST +H Sbjct: 610 ELTYKI--YDGGDFGFAIDPNTGEIYINRKITYDEYDLWKVLVTVNDNGQPSQTSTATIH 667 Query: 675 IKIED 679 + + Sbjct: 668 FTLTE 672 Score = 198 bits (484), Expect = 1e-48 Identities = 163/587 (27%), Positives = 255/587 (43%), Gaps = 55/587 (9%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 H ++ VLD ND+SP F + + E A+ GT + A D D+G N+ Y + Sbjct: 120 HVEVEVLDVNDNSPEFPRAECTVEISESAALGTRIALDAAEDSDVGSNSIQSYELS---- 175 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASPV 126 + + R+DG + L+ LDRE A + + + A D P Sbjct: 176 ------------ENSHFSIDVITRVDGVKYAELVLVKELDREARAFFALKLVAADGGHPP 223 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 S + + V + D NDN P F Y+V V ED V ++ + A D D G N Sbjct: 224 R---SGSTNVTVKVKDANDNSPLFDHSHYSVDVPEDTPV--EALLLDLNAIDPDEGLNGQ 278 Query: 187 IRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 + Y + + F +D +G ++L +DYE +Y + ++A D G + ++ Sbjct: 279 VVYEFGKQVTTEIRQLFKLDYKTGYLTLQSPVDYEDETTYEIDVQATDLGHNPVPSVCKI 338 Query: 244 LINIRDVNDNAPRFY-TSLFQES-----VSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297 +INIRDVNDN P TS+ + VSE + + D D G N +++ T+ Sbjct: 339 IINIRDVNDNPPEIIITSITSVTDGVAHVSEATGPDILVALISIKDKDTGANGQVSCTLN 398 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357 GN L + S + T LDRE A+Y L V A D G PP Sbjct: 399 GGH--GNFRLKRAYEG-SYTIVTMAPLDREKIAEYNLTVVAEDFGVPPLRTVTQYIVRLT 455 Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRG--RFS 413 F YE + E++ PGT + T+ A+D D + + YE+ +T RF+ Sbjct: 456 DVNDNAPAFSAKIYEGFIEENQLPGTYITTILASDQDSGLNGEITYELFDSDTNSVSRFA 515 Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFEN 471 I +Q G + Q +++ +R L V A+D G + A++ IN+ D N+ P + Sbjct: 516 IMNQAGN--VYALQSFNYEVTKRLDLRVQASDRGWPQLHNNAILIINVVDQNDNTPFITH 573 Query: 472 APYTASVFE-----DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 P E DAP G V + A DSD G+NA++TY + D F I Sbjct: 574 PPLINGSAEIQLPRDAPPGYIVTRIIAKDSDAGLNAELTYKIYDG--------GDFGFAI 625 Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 +P TG I N+ + + + + VT D G PS + T + ++ + Sbjct: 626 DPNTGEIYINRKITYDEYDLWKVLVTVNDNGQPSQTSTATIHFTLTE 672 Score = 198 bits (483), Expect = 2e-48 Identities = 164/577 (28%), Positives = 255/577 (44%), Gaps = 29/577 (5%) Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDGG-SPSRSNTTQL 243 IR+ ++ +T G ++ + +D E++ R+ R VI S + + Sbjct: 62 IRFKLMSPSTGSFIRFRESDGRLTAEERVDRERICKRNPRCVITFDVAFVSAEQFELFHV 121 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 + + DVNDN+P F + +SE+ +G I A D+D G N+ +Y +++ + Sbjct: 122 EVEVLDVNDNSPEFPRAECTVEISESAALGTRIALDAAEDSDVGSNSIQSYELSENSHF- 180 Query: 304 NVDLPITIDP-RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 ++D+ +D + + +LDRE +A + L + A DGG PPRS + Sbjct: 181 SIDVITRVDGVKYAELVLVKELDREARAFFALKLVAADGGHPPRSGSTNVTVKVKDANDN 240 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGG-NTRGRFSITSQNG 419 F Y V++ ED P ++ L A D DE + ++ YE T R Sbjct: 241 SPLFDHSHYSVDVPEDTPVEALLLDLNAIDPDEGLNGQVVYEFGKQVTTEIRQLFKLDYK 300 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYT-- 475 G +T+ P+D++ E Y + V ATD G + INI D N+ P T Sbjct: 301 TGYLTLQSPVDYEDETTYEIDVQATDLGHNPVPSVCKIIINIRDVNDNPPEIIITSITSV 360 Query: 476 ----ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 A V E V ++S D D G N Q++ +L+ N + + + Sbjct: 361 TDGVAHVSEATGPDILVALISIKDKDTGANGQVSCTLNGGHGNFRLKRAYEG------SY 414 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 I T LDRE ++ Y LTV A D GVP L T + + DVNDN P F ++Y I Sbjct: 415 TIVTMAPLDREKIAEYNLTVVAEDFGVPPLRTVTQYIVRLTDVNDNAPAFSAKIYEGFIE 474 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKALDRESV 650 E+ L GT ++ + A+D D GLNG I YEL D S F I +G + ++ + E Sbjct: 475 ENQLPGTYITTILASDQDSGLNGEITYELFDSDTNSVSRFAIMNQAGNVYALQSFNYEVT 534 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL-----TFYISENSPIGTT 705 DL+ A D G P + I+ I + D ND+ P L + ++P G Sbjct: 535 KRLDLRVQASDRGWPQLHNNAILIINVVDQNDNTPFITHPPLINGSAEIQLPRDAPPGYI 594 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 + I A D D G NA + Y I G D F+++ G Sbjct: 595 VTRIIAKDSDAGLNAELTYKIYDGGDF-GFAIDPNTG 630 Score = 157 bits (380), Expect = 5e-36 Identities = 117/375 (31%), Positives = 177/375 (47%), Gaps = 23/375 (6%) Query: 432 KQERRYVLTVS-ATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 K+ R V+T A S + + V++ + D N+ +P F A T + E A +GT + + Sbjct: 97 KRNPRCVITFDVAFVSAEQFELFHVEVEVLDVNDNSPEFPRAECTVEISESAALGTRIAL 156 Query: 491 VSATDSDVGINAQITYSLS--SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 +A DSDVG N+ +Y LS S S + + D + + K LDRE + + Sbjct: 157 DAAEDSDVGSNSIQSYELSENSHFSIDVITRVD-----GVKYAELVLVKELDREARAFFA 211 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 L + A DGG P S +T+V + V D NDN P+F Y+ ++ ED V + + A D Sbjct: 212 LKLVAADGGHPPRSGSTNVTVKVKDANDNSPLFDHSHYSVDVPEDTPVEALLLDLNAIDP 271 Query: 609 DVGLNGRIHYELDPKDREE--GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP 666 D GLNG++ YE + E F +D +G + +D E T+++ A D G P Sbjct: 272 DEGLNGQVVYEFGKQVTTEIRQLFKLDYKTGYLTLQSPVDYEDETTYEIDVQATDLGHNP 331 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTF------YISENSPIGTTIGEIRAHDPDEGPNA 720 S + I I D+ND+PP +T ++SE + + I D D G N Sbjct: 332 VPSVCKIIINIRDVNDNPPEIIITSITSVTDGVAHVSEATGPDILVALISIKDKDTGANG 391 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWND 777 V ++ GG +F L+ R +VTM LD E + Y L + A PPL Sbjct: 392 QVSCTLNGGH--GNFRLK-RAYEGSYTIVTMAPLDREKIAE-YNLTVVAEDFGVPPLRTV 447 Query: 778 VRVEILVTDVNDNAP 792 + + +TDVNDNAP Sbjct: 448 TQYIVRLTDVNDNAP 462 Score = 137 bits (332), Expect = 4e-30 Identities = 98/302 (32%), Positives = 145/302 (48%), Gaps = 22/302 (7%) Query: 96 SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155 S ++T A LDREK+A Y + V A D P L + V + D NDN P FS K Y Sbjct: 413 SYTIVTMAPLDREKIAEYNLTVVAEDFGVPP---LRTVTQYIVRLTDVNDNAPAFSAKIY 469 Query: 156 TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQM--QFSIDSLSGDVSLVK 213 ++E+ I I A+D D G N I Y + +T +F+I + +G+V ++ Sbjct: 470 EGFIEEN--QLPGTYITTILASDQDSGLNGEITYELFDSDTNSVSRFAIMNQAGNVYALQ 527 Query: 214 TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRF-YTSLFQESVS----E 268 + +YE + L ++A D G P N L+IN+ D NDN P + L S Sbjct: 528 SFNYEVTKRLDLRVQASDRGWPQLHNNAILIINVVDQNDNTPFITHPPLINGSAEIQLPR 587 Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328 + P GY + R+ A D+D G+NAELTY K Y G D IDP +G +Y + ++ + Sbjct: 588 DAPPGYIVTRIIAKDSDAGLNAELTY----KIYDGG-DFGFAIDPNTGEIYINRKITYDE 642 Query: 329 QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388 +++LVT D G P +++TAT G + E EDEP +V + Sbjct: 643 YDLWKVLVTVNDNGQPSQTSTATIHFTLTESAPSN-----GNFYDEREEDEPKQWTLVLI 697 Query: 389 TA 390 A Sbjct: 698 LA 699 Score = 69.3 bits (162), Expect = 1e-09 Identities = 75/291 (25%), Positives = 134/291 (46%), Gaps = 25/291 (8%) Query: 628 GSFV-IDPASGVIRTNKALDRESVATHDLKAV-AIDGGTPPQSSTVIVHIKIE--DINDS 683 GSF+ + G + + +DRE + + + V D + H+++E D+ND+ Sbjct: 72 GSFIRFRESDGRLTAEERVDRERICKRNPRCVITFDVAFVSAEQFELFHVEVEVLDVNDN 131 Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE--TR- 740 P F T ISE++ +GT I A D D G N++ Y + +++ FS++ TR Sbjct: 132 SPEFPRAECTVEISESAALGTRIALDAAEDSDVGSNSIQSYEL---SENSHFSIDVITRV 188 Query: 741 QGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDF 797 G AELV + +LD E+ R + L + AA PP V + V D NDN+P+ Sbjct: 189 DGVKYAELVLVKELDREA-RAFFALKLVAADGGHPPRSGSTNVTVKVKDANDNSPLFDHS 247 Query: 798 QIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRI---LSGNNANLILLNETTGSMTLS 852 + +D + A D D + ++ Y ++ L L+ TG +TL Sbjct: 248 HYSVDVPEDTPVEALLLDLNAIDPDEGLNGQVVYEFGKQVTTEIRQLFKLDYKTGYLTLQ 307 Query: 853 PQLNTNVPKLATMEVSVTD-GVNEIKAMMQ--LSVRLITE---EMLLNSIT 897 ++ ++V TD G N + ++ + +++R + + E+++ SIT Sbjct: 308 SPVDYEDETTYEIDVQATDLGHNPVPSVCKIIINIRDVNDNPPEIIITSIT 358 >UniRef50_UPI0000E20B47 Cluster: PREDICTED: similar to Protocadherin gamma B4 precursor (PCDH-gamma-B4) isoform 20; n=2; Catarrhini|Rep: PREDICTED: similar to Protocadherin gamma B4 precursor (PCDH-gamma-B4) isoform 20 - Pan troglodytes Length = 749 Score = 210 bits (514), Expect = 3e-52 Identities = 127/424 (29%), Positives = 213/424 (50%), Gaps = 16/424 (3%) Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQ-DGGSPSRSNTTQLLINIRDVNDNAPRFY 258 F++ + SG++ + LD E++ + + + + + N + + I D+ND+ P+F Sbjct: 75 FTVSAESGELLVSSRLDREEICGKKPACALEFEAVAENPLNFYHVNVEIEDINDHTPKFT 134 Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV 318 + F+ +SE+ G + A+DAD G N Y ++ D+ ++ + + + Sbjct: 135 QNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHFSLINKEKSDGSKYPEM 194 Query: 319 YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAED 378 LDRE Q Y L +TA D G PP S+TA F Y V L+E+ Sbjct: 195 VLKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDIYRVSLSEN 254 Query: 379 EPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436 PGT V+ +TATD DE + + + + + +F + S G ITV LDF++ + Sbjct: 255 VYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQFDLNSNTGE--ITVLNTLDFEEVKE 312 Query: 437 YVLTVSATDSGGRSDTAMVQINITDANNYAP--VFENAPYTASVFEDAPIGTTVLVVSAT 494 Y + + A D GG V++ + D N+ AP +F++ P + EDA +GT + ++ Sbjct: 313 YSIVLEARDGGGMIAQCTVEVEVIDENDNAPEVIFQSLPNL--IMEDAELGTHIALLKVR 370 Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554 D D N ++T L ++ + + + T + T+ +LDRE Y +TVTAR Sbjct: 371 DKDSRHNGEVTCKLEGDVPFKILTS-------SRNTYKLVTDAVLDREQNPEYNITVTAR 423 Query: 555 DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614 D G P LS ++ + + + DVNDN PVF Q Y ++ E+ G S+SQV A+D D+G NG Sbjct: 424 DRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVSASDPDLGPNG 483 Query: 615 RIHY 618 ++ Y Sbjct: 484 QVSY 487 Score = 196 bits (479), Expect = 5e-48 Identities = 127/367 (34%), Positives = 191/367 (52%), Gaps = 16/367 (4%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDAD-EDNRL-HYEITGGNTRGRFSITSQNGRGL- 422 F +E++++E PGT + +A DAD N L +Y+++ + + +G Sbjct: 133 FTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHFSLINKEKSDGSKYP 192 Query: 423 -ITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVF 479 + + PLD ++++ Y LT++A D G S TA + + +TDAN+ APVF Y S+ Sbjct: 193 EMVLKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDIYRVSLS 252 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E+ GTTVL V+ATD D G+NA+IT+S S A QF +N TG IT L Sbjct: 253 ENVYPGTTVLQVTATDQDEGVNAEITFSFSE-------ASQITQFDLNSNTGEITVLNTL 305 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 D E + Y + + ARDGG + VE+ V+D NDN P Q IMEDA +GT Sbjct: 306 DFEEVKEYSIVLEARDGG--GMIAQCTVEVEVIDENDNAPEVIFQSLPNLIMEDAELGTH 363 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 ++ + D D NG + +L+ D + + T+ LDRE +++ A Sbjct: 364 IALLKVRDKDSRHNGEVTCKLEG-DVPFKILTSSRNTYKLVTDAVLDREQNPEYNITVTA 422 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 D G PP SS+ + + I D+ND+ PVF +++EN+P G +I ++ A DPD GPN Sbjct: 423 RDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVSASDPDLGPN 482 Query: 720 AVVHYSI 726 V Y I Sbjct: 483 GQVSYCI 489 Score = 182 bits (444), Expect = 1e-43 Identities = 119/389 (30%), Positives = 187/389 (48%), Gaps = 30/389 (7%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 H + + D NDH+P F +E + E A GT + A D DIG N Y Sbjct: 118 HVNVEIEDINDHTPKFTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNY------- 170 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASPV 126 L+P D + + + DG + ++ + LDREK Y + + A D +P Sbjct: 171 -QLSPSD--------HFSLINKEKSDGSKYPEMVLKTPLDREKQKSYHLTLTALDFGAP- 220 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 LSSTA IHV + D NDN P FS+ Y VS+ E +V + ++ ATD D G N+ Sbjct: 221 --PLSSTAQIHVLVTDANDNAPVFSQDIYRVSLSE--NVYPGTTVLQVTATDQDEGVNAE 276 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 I ++ + QF ++S +G+++++ TLD+E+V+ Y +V+ A+DGG T + + Sbjct: 277 ITFSFSEASQITQFDLNSNTGEITVLNTLDFEEVKEYSIVLEARDGGGMIAQCTVE--VE 334 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + D NDNAP + E+ +G I ++ D D N E+T + G+V Sbjct: 335 VIDENDNAPEVIFQSLPNLIMEDAELGTHIALLKVRDKDSRHNGEVTCKL-----EGDVP 389 Query: 307 LPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 I R+ + + T LDRE +Y + VTA D G PP S++++ Sbjct: 390 FKILTSSRNTYKLVTDAVLDREQNPEYNITVTARDRGKPPLSSSSSITLHIGDVNDNAPV 449 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDAD 394 F Y V +AE+ PPG + ++A+D D Sbjct: 450 FSQSSYIVHVAENNPPGASISQVSASDPD 478 Score = 175 bits (425), Expect = 2e-41 Identities = 126/430 (29%), Positives = 212/430 (49%), Gaps = 22/430 (5%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F + SG LL + LDRE++ +A V++ + ++V I D ND+ P+ Sbjct: 75 FTVSAESGELLVSSRLDREEICGKKPACALEFEA--VAENPLNFYHVNVEIEDINDHTPK 132 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG-- 207 F++ ++ + + E ++ A DAD+G+N+ Y + + + + G Sbjct: 133 FTQNSFELQISESAQPGTRFILGS--AHDADIGSNTLQNYQLSPSDHFSLINKEKSDGSK 190 Query: 208 --DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265 ++ L LD E+ +SY L + A D G+P S+T Q+ + + D NDNAP F +++ S Sbjct: 191 YPEMVLKTPLDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDIYRVS 250 Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325 +SENV G ++++V A D DEGVNAE+T++ ++ DL + +G + LD Sbjct: 251 LSENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQFDL----NSNTGEITVLNTLD 306 Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 E +Y +++ A DGG T F + ED GT + Sbjct: 307 FEEVKEYSIVLEARDGGGMIAQCTVEVEVIDENDNAPEVIFQ--SLPNLIMEDAELGTHI 364 Query: 386 VTLTATDADEDNRLHYEIT---GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 L D +D+R + E+T G+ + +S+N L+T A LD +Q Y +TV+ Sbjct: 365 ALLKVRD--KDSRHNGEVTCKLEGDVPFKILTSSRNTYKLVTDAV-LDREQNPEYNITVT 421 Query: 443 ATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 A D G S ++ + ++I D N+ APVF + Y V E+ P G ++ VSA+D D+G Sbjct: 422 ARDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVSASDPDLGP 481 Query: 501 NAQITYSLSS 510 N Q++Y + S Sbjct: 482 NGQVSYCIVS 491 Score = 157 bits (380), Expect = 5e-36 Identities = 117/384 (30%), Positives = 173/384 (45%), Gaps = 16/384 (4%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 V + I D N++ P F + + E A GT ++ SA D+D+G N Y LS Sbjct: 119 VNVEIEDINDHTPKFTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHF 178 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 + P+ T LDRE Y LT+TA D G P LS T + + V D Sbjct: 179 SLINKEKSDGSKYPEMVLKTP---LDREKQKSYHLTLTALDFGAPPLSSTAQIHVLVTDA 235 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634 NDN PVF Q +Y ++ E+ GT+V QV ATD D G+N I + + F ++ Sbjct: 236 NDNAPVFSQDIYRVSLSENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQIT-QFDLNS 294 Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694 +G I LD E V + + A DGG TV +++ D ND+ P L Sbjct: 295 NTGEITVLNTLDFEEVKEYSIVLEARDGGGMIAQCTV--EVEVIDENDNAPEVIFQSLPN 352 Query: 695 YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDL 754 I E++ +GT I ++ D D N V ++G F + T + +LVT L Sbjct: 353 LIMEDAELGTHIALLKVRDKDSRHNGEVTCKLEG---DVPFKILT-SSRNTYKLVTDAVL 408 Query: 755 DYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG 811 D E +Y + + A PPL + + + + DVNDNAPV I + ++ P Sbjct: 409 DREQ-NPEYNITVTARDRGKPPLSSSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGA 467 Query: 812 PFGRVPAYDADV--TDKLQYRILS 833 +V A D D+ ++ Y I+S Sbjct: 468 SISQVSASDPDLGPNGQVSYCIVS 491 Score = 132 bits (320), Expect = 1e-28 Identities = 99/320 (30%), Positives = 148/320 (46%), Gaps = 22/320 (6%) Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E+ P G+ VV +D+G + Q + +S+E F ++ ++G + + L Sbjct: 39 EEMPKGS---VVGNLATDLGFSVQELPTRKLRVSSEK-----PYFTVSAESGELLVSSRL 90 Query: 540 DRETMSGYLLTVTARDGGVPSLS-DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 DRE + G V + V + + D+ND+ P F Q + I E A GT Sbjct: 91 DREEICGKKPACALEFEAVAENPLNFYHVNVEIEDINDHTPKFTQNSFELQISESAQPGT 150 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDR-----EEGSFVIDPASGVIRTNKALDRESVATH 653 A DAD+G N +Y+L P D +E S V++T LDRE ++ Sbjct: 151 RFILGSAHDADIGSNTLQNYQLSPSDHFSLINKEKSDGSKYPEMVLKT--PLDREKQKSY 208 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713 L A+D G PP SST +H+ + D ND+ PVF D +SEN GTT+ ++ A D Sbjct: 209 HLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDIYRVSLSENVYPGTTVLQVTATD 268 Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SP 772 DEG NA + +S F L + G E+ + LD+E K+Y +V+ A Sbjct: 269 QDEGVNAEITFSFSEASQITQFDLNSNTG----EITVLNTLDFEEV-KEYSIVLEARDGG 323 Query: 773 PLWNDVRVEILVTDVNDNAP 792 + VE+ V D NDNAP Sbjct: 324 GMIAQCTVEVEVIDENDNAP 343 Score = 126 bits (303), Expect = 1e-26 Identities = 93/296 (31%), Positives = 146/296 (49%), Gaps = 34/296 (11%) Query: 4 PFCIHQQINVL--DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 P QI+VL D ND++PVF Y S+ E GTTVL + ATDQD G NAE+ ++ Sbjct: 221 PLSSTAQIHVLVTDANDNAPVFSQDIYRVSLSENVYPGTTVLQVTATDQDEGVNAEITFS 280 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121 + T F ++ +G + +LD E+V Y+++++A D Sbjct: 281 FSEASQIT-------------------QFDLNSNTGEITVLNTLDFEEVKEYSIVLEARD 321 Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181 ++ T+ V +ID+NDN P+ ++ + ED + + IA +K D D Sbjct: 322 GGGMIAQ-----CTVEVEVIDENDNAPEVIFQSLPNLIMEDAELGTH--IALLKVRDKDS 374 Query: 182 GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRS 238 N + + G + F I + S + + T LD EQ Y + + A+D G P S Sbjct: 375 RHNGEVTCKLEG---DVPFKILTSSRNTYKLVTDAVLDREQNPEYNITVTARDRGKPPLS 431 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294 +++ + ++I DVNDNAP F S + V+EN P G SI +V A D D G N +++Y Sbjct: 432 SSSSITLHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVSASDPDLGPNGQVSY 487 Score = 98.3 bits (234), Expect = 3e-18 Identities = 77/271 (28%), Positives = 121/271 (44%), Gaps = 10/271 (3%) Query: 626 EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI--KIEDINDS 683 E+ F + SG + + LDRE + A A++ ++ H+ +IEDIND Sbjct: 71 EKPYFTVSAESGELLVSSRLDREEICGKK-PACALEFEAVAENPLNFYHVNVEIEDINDH 129 Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 P F + ISE++ GT AHD D G N + +Y + D + + E GS Sbjct: 130 TPKFTQNSFELQISESAQPGTRFILGSAHDADIGSNTLQNYQLSPSDHFSLINKEKSDGS 189 Query: 744 DKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQII 800 E+V LD E +K Y L + A +PPL + ++ +LVTD NDNAPV Sbjct: 190 KYPEMVLKTPLDREK-QKSYHLTLTALDFGAPPLSSTAQIHVLVTDANDNAPVFSQDIYR 248 Query: 801 FNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTN 858 + ++ +P +V A D D V ++ + + LN TG +T+ L+ Sbjct: 249 VSLSENVYPGTTVLQVTATDQDEGVNAEITFSFSEASQITQFDLNSNTGEITVLNTLDFE 308 Query: 859 VPKLATMEVSVTDGVNEIKAMMQLSVRLITE 889 K ++ + DG I A + V +I E Sbjct: 309 EVKEYSIVLEARDGGGMI-AQCTVEVEVIDE 338 Score = 58.8 bits (136), Expect = 2e-06 Identities = 44/116 (37%), Positives = 60/116 (51%), Gaps = 11/116 (9%) Query: 243 LLINIRDVNDNAPR-FYTSLFQE--SVSENVPI----GYSIVRVQAYDADEGVNAELTYT 295 L + + D NDNAPR Y +L + ++ + VP GY + +V A DAD G NA L+Y Sbjct: 492 LRVLVDDRNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYH 551 Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 + G L + R+G V T+ L + +LLV DGG PP SATAT Sbjct: 552 VLQASEPGLFSLGL----RTGEVRTARALGDRDAVRQRLLVAVRDGGQPPLSATAT 603 Score = 49.2 bits (112), Expect = 0.002 Identities = 33/84 (39%), Positives = 47/84 (55%), Gaps = 3/84 (3%) Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL-DRESVATHDL 655 G V++V A DAD G N + Y + + E G F + +G +RT +AL DR++V L Sbjct: 529 GYLVTKVVAVDADSGHNAWLSYHV-LQASEPGLFSLGLRTGEVRTARALGDRDAVRQRLL 587 Query: 656 KAVAIDGGTPPQSSTVIVHIKIED 679 AV DGG PP S+T +H+ D Sbjct: 588 VAVR-DGGQPPLSATATLHLVFAD 610 Score = 44.8 bits (101), Expect = 0.035 Identities = 26/81 (32%), Positives = 43/81 (53%), Gaps = 2/81 (2%) Query: 170 VIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTL-DYEQVRSYRLVIR 228 ++ K+ A DAD G N+ + Y ++ + FS+ +G+V + L D + VR RL++ Sbjct: 531 LVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAVRQ-RLLVA 589 Query: 229 AQDGGSPSRSNTTQLLINIRD 249 +DGG P S T L + D Sbjct: 590 VRDGGQPPLSATATLHLVFAD 610 Score = 43.6 bits (98), Expect = 0.080 Identities = 18/52 (34%), Positives = 29/52 (55%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 +++ D ND++PVF Y V E G ++ + A+D D+G N +V Y I Sbjct: 438 LHIGDVNDNAPVFSQSSYIVHVAENNPPGASISQVSASDPDLGPNGQVSYCI 489 Score = 37.5 bits (83), Expect = 5.3 Identities = 39/127 (30%), Positives = 60/127 (47%), Gaps = 16/127 (12%) Query: 455 VQINITDANNYAP-VFENA--PYTASVFEDAPI----GTTVLVVSATDSDVGINAQITYS 507 +++ + D N+ AP V A P +++F+ P G V V A D+D G NA ++Y Sbjct: 492 LRVLVDDRNDNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYH 551 Query: 508 LSSEISNEAVAHHDQQFVINPQTGAITTNKLL-DRETMSGYLLTVTARDGGVPSLSDTTD 566 + A F + +TG + T + L DR+ + LL V RDGG P LS T Sbjct: 552 VLQ-------ASEPGLFSLGLRTGEVRTARALGDRDAVRQRLL-VAVRDGGQPPLSATAT 603 Query: 567 VEISVVD 573 + + D Sbjct: 604 LHLVFAD 610 >UniRef50_A7SSF1 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 479 Score = 210 bits (514), Expect = 3e-52 Identities = 145/491 (29%), Positives = 233/491 (47%), Gaps = 34/491 (6%) Query: 97 GALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT 156 G + SLD E+ + + + A D+ P S ++ A + ++++D NDN P F Y Sbjct: 7 GVITLTKSLDSERNTTFNLTITAHDKGMP-SLETATRAIVVIDVVDTNDNNPIFELSLYE 65 Query: 157 VSVDEDISVTDN-------PV---IAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206 ++ E+ + + PV I ++ +D D NS + ++ G+ F + S S Sbjct: 66 TTILENTTAGSSVMVSEYAPVGQTILRLTVSDNDTAENSQLNLRVVSGDPNSTFFL-SNS 124 Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 G++S+ + LDYE+++ Y L + A D G P ++I IRD NDN P F L++ Sbjct: 125 GEISIARKLDYERLQMYNLTVVAWDSGKPVLQSLKPANVVIRIRDDNDNQPVFSRDLYEA 184 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 V EN+ G +V+V+A DAD N L Y+M + ++ +G +Y S L Sbjct: 185 WVLENITAGQFVVQVKAKDADYQQNGRLVYSMVRN------NSKFRVNETTGEIYLSESL 238 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 D E +Y + A+D G P+S++ + F Y+ + E+ P GT Sbjct: 239 DFEETKEYVFGIIASDSGVEPKSSSTSVRVIVMDVNDNVPTFDRFLYKSTVRENSPVGTT 298 Query: 385 VVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 + + A D D + ++ Y I GNT F I + G +TV + +DF+ + Y LT+ Sbjct: 299 AIKVQAIDTDTGSNAKIEYIIASGNTNNSFDI---DNHGFVTVNKAIDFETRKIYNLTIM 355 Query: 443 ATDSGGRSDTAMVQI--NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 A D G T++V + I D N+ PVF+ Y ++E+ I ++ V A+DSD G Sbjct: 356 ARDCGDPVLTSIVSVVLLIEDENDNPPVFDLPYYFVRMYENVSIRADIIRVHASDSDSGF 415 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560 N++I YS V + F IN TG I T +D E Y +V A D G+P Sbjct: 416 NSEIRYSF-------PVGFVVKPFAINANTGMIYTRHEIDFEEKRVYEFSVIASDQGIPV 468 Query: 561 LSDTTDVEISV 571 L D V + V Sbjct: 469 LRDVAIVRVDV 479 Score = 210 bits (513), Expect = 4e-52 Identities = 154/489 (31%), Positives = 239/489 (48%), Gaps = 34/489 (6%) Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ--LLINIRDVNDNAPRFYTSLFQE 264 G ++L K+LD E+ ++ L I A D G PS T+ ++I++ D NDN P F SL++ Sbjct: 7 GVITLTKSLDSERNTTFNLTITAHDKGMPSLETATRAIVVIDVVDTNDNNPIFELSLYET 66 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI---DPRS------ 315 ++ EN G S++ V Y A G L T++D D N L + + DP S Sbjct: 67 TILENTTAGSSVM-VSEY-APVGQTI-LRLTVSDNDTAENSQLNLRVVSGDPNSTFFLSN 123 Query: 316 -GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT--ATXXXXXXXXXXXXXXFMPGQYE 372 G + + +LD E Y L V A D G P + A F YE Sbjct: 124 SGEISIARKLDYERLQMYNLTVVAWDSGKPVLQSLKPANVVIRIRDDNDNQPVFSRDLYE 183 Query: 373 VELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 + E+ G VV + A DAD ++ RL Y + N++ R + T+ G I +++ LD Sbjct: 184 AWVLENITAGQFVVQVKAKDADYQQNGRLVYSMVRNNSKFRVNETT----GEIYLSESLD 239 Query: 431 FKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 F++ + YV + A+DSG +S + V++ + D N+ P F+ Y ++V E++P+GTT Sbjct: 240 FEETKEYVFGIIASDSGVEPKSSSTSVRVIVMDVNDNVPTFDRFLYKSTVRENSPVGTTA 299 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 + V A D+D G NA+I Y ++S +N + F I+ G +T NK +D ET Y Sbjct: 300 IKVQAIDTDTGSNAKIEYIIASGNTNNS-------FDID-NHGFVTVNKAIDFETRKIYN 351 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 LT+ ARD G P L+ V + + D NDN PVF Y + E+ + + +V A+D+ Sbjct: 352 LTIMARDCGDPVLTSIVSVVLLIEDENDNPPVFDLPYYFVRMYENVSIRADIIRVHASDS 411 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 D G N I Y P F I+ +G+I T +D E ++ +A D G P Sbjct: 412 DSGFNSEIRYSF-PVGFVVKPFAINANTGMIYTRHEIDFEEKRVYEFSVIASDQGIPVLR 470 Query: 669 STVIVHIKI 677 IV + + Sbjct: 471 DVAIVRVDV 479 Score = 194 bits (474), Expect = 2e-47 Identities = 131/454 (28%), Positives = 226/454 (49%), Gaps = 26/454 (5%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI-ELVTADT 69 I+V+D ND++P+FE+ YE ++ E ++G++V+ + + A V TI L +D Sbjct: 47 IDVVDTNDNNPIFELSLYETTILENTTAGSSVM--------VSEYAPVGQTILRLTVSDN 98 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 E++ F + SG + LD E++ Y + V A D PV Sbjct: 99 DTAENSQLNLRVVSGDPNSTFFLSN-SGEISIARKLDYERLQMYNLTVVAWDSGKPVLQS 157 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L A + + I DDNDN P FS Y V E+I T + ++KA DAD N + Y Sbjct: 158 LKP-ANVVIRIRDDNDNQPVFSRDLYEAWVLENI--TAGQFVVQVKAKDADYQQNGRLVY 214 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 +++ N++ F ++ +G++ L ++LD+E+ + Y I A D G +S++T + + + D Sbjct: 215 SMVRNNSK--FRVNETTGEIYLSESLDFEETKEYVFGIIASDSGVEPKSSSTSVRVIVMD 272 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 VNDN P F L++ +V EN P+G + ++VQA D D G NA++ Y + +GN + Sbjct: 273 VNDNVPTFDRFLYKSTVRENSPVGTTAIKVQAIDTDTGSNAKIEYIIA----SGNTNNSF 328 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 ID G+V + +D ET+ Y L + A D GDP ++ + F Sbjct: 329 DID-NHGFVTVNKAIDFETRKIYNLTIMARDCGDPVLTSIVSVVLLIEDENDNPPVFDLP 387 Query: 370 QYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 Y V + E+ ++ + A+D+D ++ + Y G F+I + G+I Sbjct: 388 YYFVRMYENVSIRADIIRVHASDSDSGFNSEIRYSFPVGFVVKPFAINANT--GMIYTRH 445 Query: 428 PLDFKQERRYVLTVSATDSG--GRSDTAMVQINI 459 +DF+++R Y +V A+D G D A+V++++ Sbjct: 446 EIDFEEKRVYEFSVIASDQGIPVLRDVAIVRVDV 479 Score = 194 bits (473), Expect = 3e-47 Identities = 147/478 (30%), Positives = 232/478 (48%), Gaps = 42/478 (8%) Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGRS----DTAMVQINITDANNYAPVFENAP 473 N G+IT+ + LD ++ + LT++A D G S A+V I++ D N+ P+FE + Sbjct: 4 NDYGVITLTKSLDSERNTTFNLTITAHDKGMPSLETATRAIVVIDVVDTNDNNPIFELSL 63 Query: 474 YTASVFED------------APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521 Y ++ E+ AP+G T+L ++ +D+D N+Q+ + S N Sbjct: 64 YETTILENTTAGSSVMVSEYAPVGQTILRLTVSDNDTAENSQLNLRVVSGDPNSTF---- 119 Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT--TDVEISVVDVNDNEP 579 F+ N +G I+ + LD E + Y LTV A D G P L +V I + D NDN+P Sbjct: 120 --FLSN--SGEISIARKLDYERLQMYNLTVVAWDSGKPVLQSLKPANVVIRIRDDNDNQP 175 Query: 580 VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI 639 VF + LY A ++E+ G V QV A DAD NGR+ Y + R F ++ +G I Sbjct: 176 VFSRDLYEAWVLENITAGQFVVQVKAKDADYQQNGRLVYSMV---RNNSKFRVNETTGEI 232 Query: 640 RTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699 +++LD E + +A D G P+SS+ V + + D+ND+ P F+ + EN Sbjct: 233 YLSESLDFEETKEYVFGIIASDSGVEPKSSSTSVRVIVMDVNDNVPTFDRFLYKSTVREN 292 Query: 700 SPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM-VDLDYES 758 SP+GTT +++A D D G NA + Y I G+ +NSF + D VT+ +D+E+ Sbjct: 293 SPVGTTAIKVQAIDTDTGSNAKIEYIIASGNTNNSFDI------DNHGFVTVNKAIDFET 346 Query: 759 PRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR 815 RK Y L I A P L + V V +L+ D NDN PV Y++ R Sbjct: 347 -RKIYNLTIMARDCGDPVLTSIVSVVLLIEDENDNPPVFDLPYYFVRMYENVSIRADIIR 405 Query: 816 VPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 V A D+D +++Y G +N TG + +++ ++ V +D Sbjct: 406 VHASDSDSGFNSEIRYSFPVGFVVKPFAINANTGMIYTRHEIDFEEKRVYEFSVIASD 463 Score = 98.7 bits (235), Expect = 2e-18 Identities = 70/226 (30%), Positives = 115/226 (50%), Gaps = 25/226 (11%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ V+D ND+ P F+ Y+++VRE + GTT + ++A D D G NA++EY I + +T Sbjct: 267 RVIVMDVNDNVPTFDRFLYKSTVRENSPVGTTAIKVQAIDTDTGSNAKIEYII--ASGNT 324 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N F ID G + ++D E Y + + A D PV Sbjct: 325 NNS-----------------FDIDNH-GFVTVNKAIDFETRKIYNLTIMARDCGDPV--- 363 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 L+S ++ + I D+NDN P F Y V + E++S+ + I ++ A+D+D G NS IRY Sbjct: 364 LTSIVSVVLLIEDENDNPPVFDLPYYFVRMYENVSIRAD--IIRVHASDSDSGFNSEIRY 421 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP 235 + G F+I++ +G + +D+E+ R Y + A D G P Sbjct: 422 SFPVGFVVKPFAINANTGMIYTRHEIDFEEKRVYEFSVIASDQGIP 467 Score = 71.7 bits (168), Expect = 3e-10 Identities = 79/278 (28%), Positives = 126/278 (45%), Gaps = 34/278 (12%) Query: 637 GVIRTNKALDRESVATHDLKAVAIDGGTPP--QSSTVIVHIKIEDINDSPPVFESDCL-- 692 GVI K+LD E T +L A D G P ++ IV I + D ND+ P+FE Sbjct: 7 GVITLTKSLDSERNTTFNLTITAHDKGMPSLETATRAIVVIDVVDTNDNNPIFELSLYET 66 Query: 693 ----------TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 + +SE +P+G TI + D D N+ ++ + GD +++F L Sbjct: 67 TILENTTAGSSVMVSEYAPVGQTILRLTVSDNDTAENSQLNLRVVSGDPNSTFFL----- 121 Query: 743 SDKAELVTMVDLDYESPRKKYELVIRA--ASPPLWNDVR---VEILVTDVNDNAPVMKDF 797 S+ E+ LDYE + Y L + A + P+ ++ V I + D NDN PV Sbjct: 122 SNSGEISIARKLDYER-LQMYNLTVVAWDSGKPVLQSLKPANVVIRIRDDNDNQPVFS-- 178 Query: 798 QIIFNNYK-DCFPVGPFG-RVPAYDADVTD--KLQYRILSGNNANLILLNETTGSMTLSP 853 + ++ + + G F +V A DAD +L Y ++ N+ +NETTG + LS Sbjct: 179 RDLYEAWVLENITAGQFVVQVKAKDADYQQNGRLVYSMVRNNSK--FRVNETTGEIYLSE 236 Query: 854 QLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEM 891 L+ K + +D E K+ SVR+I ++ Sbjct: 237 SLDFEETKEYVFGIIASDSGVEPKS-SSTSVRVIVMDV 273 >UniRef50_Q9BYE9 Cluster: Protocadherin LKC precursor; n=17; Theria|Rep: Protocadherin LKC precursor - Homo sapiens (Human) Length = 1310 Score = 210 bits (514), Expect = 3e-52 Identities = 214/767 (27%), Positives = 354/767 (46%), Gaps = 90/767 (11%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F + ++G + ++LD E + + V + +D V + V + D NDN P Sbjct: 70 FAVTPKTGEVKLASALDYETLYTFKVTISVSDPYIQVQREML------VIVEDRNDNAPV 123 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI-----IGGNTQMQFSIDS 204 F ++ S++E + V V+ + A D D+G+ + Y+I G+++ F I + Sbjct: 124 FQNTAFSTSINETLPV--GSVVFSVLAVDKDMGSAGMVVYSIEKVIPSTGDSEHLFRILA 181 Query: 205 LSGDVSLVKTLDYEQVRS-YRLVIRAQD-GGSPSRSNTTQ------LLINIRDVNDNAPR 256 +G + L +L Y + Y+L ++A D GG + T Q L I++ D D P+ Sbjct: 182 -NGSIVLNGSLSYNNKSAFYQLELKACDLGGMYHNTFTIQCSLPVFLSISVVDQPDLDPQ 240 Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316 F + SV+E+ G S++ V+A D D+G+N + Y+++ G D+ G Sbjct: 241 FVREFYSASVAEDAAKGTSVLTVEAVDGDKGINDPVIYSISYSTRPGWFDIGA-----DG 295 Query: 317 WVYTSGQLDRE----TQAKYQLLVTATD------GGDPPRSATATXXXXXXXX------- 359 + +G LDRE + QL VTAT+ G + S T Sbjct: 296 VIRVNGSLDREQLLEADEEVQLQVTATETHLNIYGQEAKVSIWVTVRVMDVNDHKPEFYN 355 Query: 360 -XXXXXXFMPGQYEVELA----EDEPPGTPV--VTLTATDADEDNRLHYEIT-GGNTRGR 411 F P + +V E P P+ +T+ D D+ + + ++ GG Sbjct: 356 CSLPACTFTPEEAQVNFTGYVDEHASPRIPIDDLTMVVYDPDKGSNGTFLLSLGGPDAEA 415 Query: 412 FSITSQNGRG------LITVAQPLDFKQERRYVLTVSATDSGGRS-DTAMVQINITDANN 464 FS++ + G L+ V+ +D++++ + V ATDS ++ AMV I++ D N+ Sbjct: 416 FSVSPERAAGSASVQVLVRVSALVDYERQTAMAVQVVATDSVSQNFSVAMVTIHLRDIND 475 Query: 465 YAPVFENAPYTASVFEDAPIGTTVL-VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523 + P F + Y +V E + G+ V + ATD D G QITYSL N A Sbjct: 476 HRPTFPQSLYVLTVPEHSATGSVVTDSIHATDPDTGAWGQITYSLLP--GNGA-----DL 528 Query: 524 FVINPQTGAITTN--KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581 F ++P +G +T +LLDRE+ + Y LT+ A DGG +LS +T ++I ++D+NDN PV Sbjct: 529 FQVDPVSGTVTVRNGELLDRESQAVYYLTLQATDGG--NLSSSTTLQIHLLDINDNAPVV 586 Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641 Y + E+ + Q D N R+ + L P +F +DP +G++R Sbjct: 587 SGS-YNIFVQEEEGNVSVTIQAHDNDEPGTNNSRLLFNLLPGPYSH-NFSLDPDTGLLRN 644 Query: 642 NKALDRESV-----ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696 LDRE++ L + D G P + V V I +EDIND+ P+F F + Sbjct: 645 LGPLDREAIDPALEGRIVLTVLVSDCGEPVLGTKVNVTITVEDINDNLPIFNQSSYNFTV 704 Query: 697 SENSPIGTTIGEIRAHDPDEGP-NAVVHYSIKGGDDSNSFSLETRQ-GSDKAE----LVT 750 E P G +G ++A D D+ N + +S+ G +N F + G+ AE L Sbjct: 705 KEEDP-GVLVGVVKAWDADQTEANNRISFSLSGSG-ANYFMIRGLVLGAGWAEGYLRLPP 762 Query: 751 MVDLDYESPRKKYELVIRAASP-PLWNDVRVEILVT--DVNDNAPVM 794 V LDYE+ + + L + A +P P + V++ V DVNDN P + Sbjct: 763 DVSLDYET-QPVFNLTVSAENPDPQGGETIVDVCVNVKDVNDNPPTL 808 Score = 190 bits (463), Expect = 5e-46 Identities = 208/747 (27%), Positives = 330/747 (44%), Gaps = 78/747 (10%) Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 P+F +V + ED+ PV A+ A+ N + Y + N F++ +G Sbjct: 24 PKFLANMTSVILPEDL-----PVGAQAFWLVAEDQDNDPLTYGMSSPNAYF-FAVTPKTG 77 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 +V L LDYE + ++++ I D P ++L+ + D NDNAP F + F S++ Sbjct: 78 EVKLASALDYETLYTFKVTISVSD---PYIQVQREMLVIVEDRNDNAPVFQNTAFSTSIN 134 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDK-DYTGNVDLPITIDPRSGWVYTSGQLDR 326 E +P+G + V A D D G + Y++ TG+ + I +G + +G L Sbjct: 135 ETLPVGSVVFSVLAVDKDMGSAGMVVYSIEKVIPSTGDSEHLFRI-LANGSIVLNGSLSY 193 Query: 327 ETQ-AKYQLLVTATD-GGDPPRSATATXXXXXXXXXXXXXX------FMPGQYEVELAED 378 + A YQL + A D GG + T F+ Y +AED Sbjct: 194 NNKSAFYQLELKACDLGGMYHNTFTIQCSLPVFLSISVVDQPDLDPQFVREFYSASVAED 253 Query: 379 EPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ--- 433 GT V+T+ A D D+ ++ + Y I+ G F I + G+I V LD +Q Sbjct: 254 AAKGTSVLTVEAVDGDKGINDPVIYSISYSTRPGWFDIGAD---GVIRVNGSLDREQLLE 310 Query: 434 -ERRYVLTVSATDS-----GGRSDTAM-VQINITDANNYAPVFENAPYTASVF--EDAPI 484 + L V+AT++ G + ++ V + + D N++ P F N A F E+A + Sbjct: 311 ADEEVQLQVTATETHLNIYGQEAKVSIWVTVRVMDVNDHKPEFYNCSLPACTFTPEEAQV 370 Query: 485 GTTVLVVSATDSDVGIN--AQITYSLSSEISNE---AVAHHDQQ-FVINPQTGA------ 532 T V + I+ + Y + ++ D + F ++P+ A Sbjct: 371 NFTGYVDEHASPRIPIDDLTMVVYDPDKGSNGTFLLSLGGPDAEAFSVSPERAAGSASVQ 430 Query: 533 --ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590 + + L+D E + + V A D + S V I + D+ND+ P F Q LY + Sbjct: 431 VLVRVSALVDYERQTAMAVQVVATDSVSQNFS-VAMVTIHLRDINDHRPTFPQSLYVLTV 489 Query: 591 MEDALVGTSVSQ-VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVI--RTNKALDR 647 E + G+ V+ + ATD D G G+I Y L P + + F +DP SG + R + LDR Sbjct: 490 PEHSATGSVVTDSIHATDPDTGAWGQITYSLLPGNGAD-LFQVDPVSGTVTVRNGELLDR 548 Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 ES A + L A DGG S+T+ +H+ DIND+ PV F E + TI Sbjct: 549 ESQAVYYLTLQATDGGNLSSSTTLQIHLL--DINDNAPVVSGSYNIFVQEEEGNVSVTI- 605 Query: 708 EIRAHDPDEGP--NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYE- 764 +AHD DE N+ + +++ G S++FSL+ D L + LD E+ E Sbjct: 606 --QAHDNDEPGTNNSRLLFNLLPGPYSHNFSLDP----DTGLLRNLGPLDREAIDPALEG 659 Query: 765 ------LVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA 818 LV P L V V I V D+NDN P+ F K+ P G V A Sbjct: 660 RIVLTVLVSDCGEPVLGTKVNVTITVEDINDNLPIFNQSSYNF-TVKEEDPGVLVGVVKA 718 Query: 819 YDADVTD---KLQYRILSGNNANLILL 842 +DAD T+ ++ + LSG+ AN ++ Sbjct: 719 WDADQTEANNRISFS-LSGSGANYFMI 744 Score = 174 bits (423), Expect = 3e-41 Identities = 221/775 (28%), Positives = 342/775 (44%), Gaps = 94/775 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+V+D D P F + Y ASV E A+ GT+VLT++A D D G N V Y+I T Sbjct: 229 ISVVDQPDLDPQFVREFYSASVAEDAAKGTSVLTVEAVDGDKGINDPVIYSISYSTRPGW 288 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR----YTVLVKATDQASPV 126 F I G G + SLDRE++ + V AT+ + Sbjct: 289 -------------------FDI-GADGVIRVNGSLDREQLLEADEEVQLQVTATETHLNI 328 Query: 127 SDRLSSTAT-IHVNIIDDNDNYPQF--------------SEKTYTVSVDEDISVTDNPVI 171 + + + + V ++D ND+ P+F ++ +T VDE S Sbjct: 329 YGQEAKVSIWVTVRVMDVNDHKPEFYNCSLPACTFTPEEAQVNFTGYVDEHASPRIPIDD 388 Query: 172 AKIKATDADVGANSAIRYAIIGGNTQMQFSI--DSLSGDVS---LVKT---LDYEQVRSY 223 + D D G+N ++ GG FS+ + +G S LV+ +DYE+ + Sbjct: 389 LTMVVYDPDKGSNGTFLLSL-GGPDAEAFSVSPERAAGSASVQVLVRVSALVDYERQTAM 447 Query: 224 RLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV-RVQAY 282 + + A D S + S + I++RD+ND+ P F SL+ +V E+ G + + A Sbjct: 448 AVQVVATDSVSQNFS-VAMVTIHLRDINDHRPTFPQSLYVLTVPEHSATGSVVTDSIHAT 506 Query: 283 DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT-SGQL-DRETQAKYQLLVTATD 340 D D G ++TY++ + DL +DP SG V +G+L DRE+QA Y L + ATD Sbjct: 507 DPDTGAWGQITYSLLPGN---GADL-FQVDPVSGTVTVRNGELLDRESQAVYYLTLQATD 562 Query: 341 GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE----D 396 GG+ +++T + G Y + + E+E G VT+ A D DE + Sbjct: 563 GGN---LSSSTTLQIHLLDINDNAPVVSGSYNIFVQEEE--GNVSVTIQAHDNDEPGTNN 617 Query: 397 NRLHYEITGGNTRGRFSITSQNG--RGLITV-AQPLDFKQERRYVLTVSATDSGGRSDTA 453 +RL + + G FS+ G R L + + +D E R VLTV +D G Sbjct: 618 SRLLFNLLPGPYSHNFSLDPDTGLLRNLGPLDREAIDPALEGRIVLTVLVSDCGEPVLGT 677 Query: 454 MVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSS 510 V + IT D N+ P+F + Y +V E+ P G V VV A D+D N +I++SLS Sbjct: 678 KVNVTITVEDINDNLPIFNQSSYNFTVKEEDP-GVLVGVVKAWDADQTEANNRISFSLSG 736 Query: 511 EISNEAVAHHDQQFVINPQTGA----ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566 +N + + V+ + + LD ET + LTV+A + D Sbjct: 737 SGANYFMI---RGLVLGAGWAEGYLRLPPDVSLDYETQPVFNLTVSAENPDPQGGETIVD 793 Query: 567 VEISVVDVNDNEPVFK-QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE------ 619 V ++V DVNDN P L + E+ V+ V A+D D I Sbjct: 794 VCVNVKDVNDNPPTLDVASLRGIRVAENGSQHGQVAVVVASDVDTSAQLEIQLVNILCTK 853 Query: 620 --LDPKDREEGSFVIDPASGV-IRTNKALDRES--VATHDLKA--VAIDGGTPPQSSTVI 672 +D G F + V I +KA+D E+ + T ++A +A D G S+ Sbjct: 854 AGVDVGSLCWGWFSVAANGSVYINQSKAIDYEACDLVTLVVRACDLATDPGFQAYSNNGS 913 Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPI-GTTIGEIRAHDPDEGPNAVVHYSI 726 + I IED+ND+ P F + TF I + + +RA D D G N V+ +SI Sbjct: 914 LLITIEDVNDNAPYFLPENKTFVIIPELVLPNREVASVRARDDDSGNNGVILFSI 968 Score = 167 bits (407), Expect = 3e-39 Identities = 215/845 (25%), Positives = 342/845 (40%), Gaps = 97/845 (11%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72 V D ND++PVF+ + S+ E G+ V ++ A D+D+G V Y+IE V T + Sbjct: 114 VEDRNDNAPVFQNTAFSTSINETLPVGSVVFSVLAVDKDMGSAGMVVYSIEKVIPSTGDS 173 Query: 73 EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD---- 128 E +FRI +L + K A Y + +KA D + Sbjct: 174 EH--------------LFRILANGSIVLNGSLSYNNKSAFYQLELKACDLGGMYHNTFTI 219 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 + S + ++++D D PQF + Y+ SV ED + + + ++A D D G N + Sbjct: 220 QCSLPVFLSISVVDQPDLDPQFVREFYSASVAEDAAKGTS--VLTVEAVDGDKGINDPVI 277 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN--------T 240 Y+I F I + G + + +LD EQ+ ++ Q + + N + Sbjct: 278 YSISYSTRPGWFDIGA-DGVIRVNGSLDREQLLEADEEVQLQVTATETHLNIYGQEAKVS 336 Query: 241 TQLLINIRDVNDNAPRFY------------------TSLFQESVSENVPIGYSIVRVQAY 282 + + + DVND+ P FY T E S +PI + + Y Sbjct: 337 IWVTVRVMDVNDHKPEFYNCSLPACTFTPEEAQVNFTGYVDEHASPRIPI--DDLTMVVY 394 Query: 283 DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG---WVYTSGQLDRETQAKYQLLVTAT 339 D D+G N ++ D P + V S +D E Q + V AT Sbjct: 395 DPDKGSNGTFLLSLGGPDAEAFSVSPERAAGSASVQVLVRVSALVDYERQTAMAVQVVAT 454 Query: 340 DGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV-TLTATDADED-- 396 D S A F Y + + E G+ V ++ ATD D Sbjct: 455 DSVSQNFSV-AMVTIHLRDINDHRPTFPQSLYVLTVPEHSATGSVVTDSIHATDPDTGAW 513 Query: 397 NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ 456 ++ Y + GN F + +G + + LD + + Y LT+ ATD G S + +Q Sbjct: 514 GQITYSLLPGNGADLFQVDPVSGTVTVRNGELLDRESQAVYYLTLQATDGGNLSSSTTLQ 573 Query: 457 INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLSSEISNE 515 I++ D N+ APV + Y V E+ G + + A D+D G N S + N Sbjct: 574 IHLLDINDNAPVVSGS-YNIFVQEEE--GNVSVTIQAHDNDEPGTNN------SRLLFNL 624 Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMSGYL-----LTVTARDGGVPSLSDTTDVEIS 570 + F ++P TG + LDRE + L LTV D G P L +V I+ Sbjct: 625 LPGPYSHNFSLDPDTGLLRNLGPLDREAIDPALEGRIVLTVLVSDCGEPVLGTKVNVTIT 684 Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREE-- 627 V D+NDN P+F Q Y + E+ G V V A DAD N RI + L Sbjct: 685 VEDINDNLPIFNQSSYNFTVKEED-PGVLVGVVKAWDADQTEANNRISFSLSGSGANYFM 743 Query: 628 -GSFVIDP--ASGVIR--TNKALDRESVATHDLKAVAIDGGTPPQSSTVI-VHIKIEDIN 681 V+ A G +R + +LD E+ +L V+ + P T++ V + ++D+N Sbjct: 744 IRGLVLGAGWAEGYLRLPPDVSLDYETQPVFNL-TVSAENPDPQGGETIVDVCVNVKDVN 802 Query: 682 DSPPVFESDCLT-FYISENSPIGTTIGEIRAHDPDEGPNAVVH----YSIKGGDDSNS-- 734 D+PP + L ++EN + + A D D + K G D S Sbjct: 803 DNPPTLDVASLRGIRVAENGSQHGQVAVVVASDVDTSAQLEIQLVNILCTKAGVDVGSLC 862 Query: 735 FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLW----NDVRVEILVTDV 787 + + + + +DYE+ LV+RA A+ P + N+ + I + DV Sbjct: 863 WGWFSVAANGSVYINQSKAIDYEA-CDLVTLVVRACDLATDPGFQAYSNNGSLLITIEDV 921 Query: 788 NDNAP 792 NDNAP Sbjct: 922 NDNAP 926 Score = 154 bits (374), Expect = 3e-35 Identities = 155/564 (27%), Positives = 256/564 (45%), Gaps = 54/564 (9%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV 425 F+ V L ED P G L A D D D L Y ++ N F++T + G + + Sbjct: 26 FLANMTSVILPEDLPVGAQAFWLVAEDQDNDP-LTYGMSSPNAYF-FAVTPKTGE--VKL 81 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 A LD++ + +T+S +D + M+ I + D N+ APVF+N ++ S+ E P+G Sbjct: 82 ASALDYETLYTFKVTISVSDPYIQVQREMLVI-VEDRNDNAPVFQNTAFSTSINETLPVG 140 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 + V V A D D+G + YS+ I + + H + + N G+I N L S Sbjct: 141 SVVFSVLAVDKDMGSAGMVVYSIEKVIPSTGDSEHLFRILAN---GSIVLNGSLSYNNKS 197 Query: 546 G-YLLTVTARD-GGVPSLSDTTD------VEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 Y L + A D GG+ + T + ISVVD D +P F ++ Y+A++ EDA G Sbjct: 198 AFYQLELKACDLGGMYHNTFTIQCSLPVFLSISVVDQPDLDPQFVREFYSASVAEDAAKG 257 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD--- 654 TSV V A D D G+N + Y + R G F I A GVIR N +LDRE + D Sbjct: 258 TSVLTVEAVDGDKGINDPVIYSISYSTR-PGWFDIG-ADGVIRVNGSLDREQLLEADEEV 315 Query: 655 -LKAVAIDGGT----PPQSSTVIVHIKIEDINDSPPVFESDCL--------------TFY 695 L+ A + ++ V +++ D+ND P F + L T Y Sbjct: 316 QLQVTATETHLNIYGQEAKVSIWVTVRVMDVNDHKPEFYNCSLPACTFTPEEAQVNFTGY 375 Query: 696 ISENSPIGTTIGEIR--AHDPDEGPNAVVHYSIKGGDDSNSFSL--ETRQGSDKAELVTM 751 + E++ I ++ +DPD+G N S+ GG D+ +FS+ E GS +++ Sbjct: 376 VDEHASPRIPIDDLTMVVYDPDKGSNGTFLLSL-GGPDAEAFSVSPERAAGSASVQVLVR 434 Query: 752 VD--LDYE-SPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVM-KDFQIIFNNYKDC 807 V +DYE ++V + ++ V I + D+ND+ P + ++ Sbjct: 435 VSALVDYERQTAMAVQVVATDSVSQNFSVAMVTIHLRDINDHRPTFPQSLYVLTVPEHSA 494 Query: 808 FPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTL--SPQLNTNVPKLA 863 + A D D ++ Y +L GN A+L ++ +G++T+ L+ + Sbjct: 495 TGSVVTDSIHATDPDTGAWGQITYSLLPGNGADLFQVDPVSGTVTVRNGELLDRESQAVY 554 Query: 864 TMEVSVTDGVNEIKAMMQLSVRLI 887 + + TDG N + + L + L+ Sbjct: 555 YLTLQATDGGN-LSSSTTLQIHLL 577 Score = 117 bits (281), Expect = 5e-24 Identities = 154/596 (25%), Positives = 239/596 (40%), Gaps = 73/596 (12%) Query: 254 APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313 AP+F ++ + E++P+G + A D D N LTY M+ + + P Sbjct: 23 APKFLANMTSVILPEDLPVGAQAFWLVAEDQD---NDPLTYGMSSPN-----AYFFAVTP 74 Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373 ++G V + LD ET +++ ++ + DP F + Sbjct: 75 KTGEVKLASALDYETLYTFKVTISVS---DPYIQVQREMLVIVEDRNDNAPVFQNTAFST 131 Query: 374 ELAEDEPPGTPVVTLTATDAD--EDNRLHYEI-----TGGNTRGRFSITSQNGRGLITVA 426 + E P G+ V ++ A D D + Y I + G++ F I + G I + Sbjct: 132 SINETLPVGSVVFSVLAVDKDMGSAGMVVYSIEKVIPSTGDSEHLFRILA---NGSIVLN 188 Query: 427 QPLDFKQERR-YVLTVSATDSGGR-SDTAMVQ--------INITDANNYAPVFENAPYTA 476 L + + Y L + A D GG +T +Q I++ D + P F Y+A Sbjct: 189 GSLSYNNKSAFYQLELKACDLGGMYHNTFTIQCSLPVFLSISVVDQPDLDPQFVREFYSA 248 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 SV EDA GT+VL V A D D GIN + YS+S + F I G I N Sbjct: 249 SVAEDAAKGTSVLTVEAVDGDKGINDPVIYSIS-------YSTRPGWFDIGAD-GVIRVN 300 Query: 537 KLLDRETM----SGYLLTVTARDGGVPSLSDTTDVEI----SVVDVNDNEPVF------- 581 LDRE + L VTA + + V I V+DVND++P F Sbjct: 301 GSLDREQLLEADEEVQLQVTATETHLNIYGQEAKVSIWVTVRVMDVNDHKPEFYNCSLPA 360 Query: 582 -------KQQLYTANIMEDALVGTSVSQVGAT--DADVGLNGRIHYELDPKDREEGSFVI 632 Q +T + E A + + D D G NG L D E S Sbjct: 361 CTFTPEEAQVNFTGYVDEHASPRIPIDDLTMVVYDPDKGSNGTFLLSLGGPDAEAFSVSP 420 Query: 633 DPASG------VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686 + A+G ++R + +D E ++ VA D S +V I + DIND P Sbjct: 421 ERAAGSASVQVLVRVSALVDYERQTAMAVQVVATD-SVSQNFSVAMVTIHLRDINDHRPT 479 Query: 687 FESDCLTFYISENSPIGTTIGE-IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK 745 F + E+S G+ + + I A DPD G + YS+ G+ ++ F ++ G+ Sbjct: 480 FPQSLYVLTVPEHSATGSVVTDSIHATDPDTGAWGQITYSLLPGNGADLFQVDPVSGTVT 539 Query: 746 AELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIF 801 + LD ES Y + L + ++I + D+NDNAPV+ IF Sbjct: 540 VRNGEL--LDRESQAVYYLTLQATDGGNLSSSTTLQIHLLDINDNAPVVSGSYNIF 593 Score = 92.3 bits (219), Expect = 2e-16 Identities = 123/520 (23%), Positives = 218/520 (41%), Gaps = 47/520 (9%) Query: 459 ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518 ++ A N AP F + + ED P+G + A D D N +TY +SS Sbjct: 16 VSVAANVAPKFLANMTSVILPEDLPVGAQAFWLVAEDQD---NDPLTYGMSSP------- 65 Query: 519 HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578 + F + P+TG + LD ET+ + +T++ D P + ++ + V D NDN Sbjct: 66 -NAYFFAVTPKTGEVKLASALDYETLYTFKVTISVSD---PYIQVQREMLVIVEDRNDNA 121 Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD---PKDREEGSFVIDPA 635 PVF+ ++ +I E VG+ V V A D D+G G + Y ++ P + A Sbjct: 122 PVFQNTAFSTSINETLPVGSVVFSVLAVDKDMGSAGMVVYSIEKVIPSTGDSEHLFRILA 181 Query: 636 SGVIRTNKALD-RESVATHDLKAVAID-GG------TPPQSSTVIVHIKIEDINDSPPVF 687 +G I N +L A + L+ A D GG T S V + I + D D P F Sbjct: 182 NGSIVLNGSLSYNNKSAFYQLELKACDLGGMYHNTFTIQCSLPVFLSISVVDQPDLDPQF 241 Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK-----GGDDSNSFSLETRQG 742 + + ++E++ GT++ + A D D+G N V YSI G D + + G Sbjct: 242 VREFYSASVAEDAAKGTSVLTVEAVDGDKGINDPVIYSISYSTRPGWFDIGADGVIRVNG 301 Query: 743 S-DKAELVTM---VDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQ 798 S D+ +L+ V L + + + A +W VR V DVND+ P +F Sbjct: 302 SLDREQLLEADEEVQLQVTATETHLNIYGQEAKVSIWVTVR----VMDVNDHKP---EF- 353 Query: 799 IIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSM-TLSPQLNT 857 +N P + V + RI ++ +++ + GS T L Sbjct: 354 --YNCSLPACTFTPEEAQVNFTGYVDEHASPRI-PIDDLTMVVYDPDKGSNGTFLLSLGG 410 Query: 858 NVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFI 917 + ++ G ++ ++++S + E ++ V D ++ F ++ + Sbjct: 411 PDAEAFSVSPERAAGSASVQVLVRVSALVDYERQTAMAVQVVATDSVSQNFSVAMVTIHL 470 Query: 918 DGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPD 957 + P +++Y+ +V + + TG+++ S A PD Sbjct: 471 RDINDHRPTFPQSLYVLTVPEHS-ATGSVVTDSIHATDPD 509 Score = 50.8 bits (116), Expect = 5e-04 Identities = 62/254 (24%), Positives = 105/254 (41%), Gaps = 32/254 (12%) Query: 11 INVLDCNDHSPVFEMQQYEA-SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +NV D ND+ P ++ V E S V + A+D D E++ L T Sbjct: 796 VNVKDVNDNPPTLDVASLRGIRVAENGSQHGQVAVVVASDVDTSAQLEIQLVNILCTKAG 855 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRA-SLDREKVARYTVLVKATDQAS-PVS 127 ++ F + + ++ ++D E T++V+A D A+ P Sbjct: 856 VD----------VGSLCWGWFSVAANGSVYINQSKAIDYEACDLVTLVVRACDLATDPGF 905 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 S+ ++ + I D NDN P F + T + ++ V N +A ++A D D G N I Sbjct: 906 QAYSNNGSLLITIEDVNDNAPYFLPENKTFVIIPEL-VLPNREVASVRARDDDSGNNGVI 964 Query: 188 RYAII--------GGNTQMQ--FSI------DSLSGDVSLVKTLDYEQVRSYRLVIRAQD 231 ++I+ G Q FSI D +G + V +LD +Y++ ++A+D Sbjct: 965 LFSILRVDFISKDGATIPFQGVFSIFTSSEADVFAGSIQPVTSLDSTLQGTYQVTVQARD 1024 Query: 232 GGS--PSRSNTTQL 243 S P TT L Sbjct: 1025 RPSLGPFLEATTTL 1038 >UniRef50_Q47W44 Cluster: Cadherin domain protein; n=1; Colwellia psychrerythraea 34H|Rep: Cadherin domain protein - Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibriopsychroerythus) Length = 2193 Score = 210 bits (513), Expect = 4e-52 Identities = 217/884 (24%), Positives = 370/884 (41%), Gaps = 50/884 (5%) Query: 34 EGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQD--VFR 91 E A + T+ A D++ G + +V YT+ T N + A D +F Sbjct: 1099 EVAPTITSASIAAAIDENSGAS-QVVYTV----TSTDNGDIATGATVYSLKAGDDAALFT 1153 Query: 92 IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151 I+ +GA+ A+ D E A Y V A+D A S+ I ++I D +D P + Sbjct: 1154 INSSTGAVTLTANPDDESKADYNFTVVASDAAGN-----STEQAITLDITDLDDVAPTIT 1208 Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSL 211 T ++DE+ V+ + +TD+ A Y++ G+ F+I+S SG V+L Sbjct: 1209 SATTATALDENSGA--GQVVYTVTSTDSGDIATGVTVYSLKAGDDAALFTINSSSGAVTL 1266 Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271 D E Y + A DG S T L +I D+++ AP ++ ++ EN Sbjct: 1267 TANPDDESKADYNFTVVASDGAGNSSEKVTTL--DITDLDEVAPTITSASSATALDENSG 1324 Query: 272 IGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK 331 G + V + D+ + Y++ D TI+ +G V + D E++A Sbjct: 1325 AGQVVYTVTSTDSGDIATGATAYSLKASDDAAL----FTINSSTGAVTLTANPDDESKAD 1380 Query: 332 YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTAT 391 Y V A+DG S + L E+ G V T+T+T Sbjct: 1381 YNFTVVASDGAG--NSTEQAITLDIIDLDDVAPTITSASSAIALDENSGAGQVVYTVTST 1438 Query: 392 DADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR 449 D + Y + G+ F+I S G +T A P D + + Y TV A+D G Sbjct: 1439 DNGDIATGATTYSLKAGDDAALFTINSSTGAVTLT-ANP-DDESKADYNFTVVASDGAGN 1496 Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509 S + ++ITD + P+ +A ++ E++ G V V++TD+ TYSL Sbjct: 1497 SSEKAITLDITDLDEVGPIITSASSATALDENSGAGQVVYTVTSTDNGDIATGATTYSLK 1556 Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569 S + VA F IN TGA+T D E+ + Y TV A DG S + + Sbjct: 1557 ---SGDDVA----LFTINSSTGAVTLTADPDDESKADYNFTVVASDGA--GNSSEKAITL 1607 Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD-ADVGLNGRIHYELDPKDREEG 628 ++D+++ P A I E++ G V V +TD D+ + Y L D + Sbjct: 1608 DIIDLDEVAPTITSAAIAAAIDENSGAGQVVYTVMSTDNGDIATDATT-YSLKSGD-DAA 1665 Query: 629 SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688 F I+ ++G + D E A ++ VA DG SS + + I D+++ P Sbjct: 1666 LFTINSSTGAVTLTANPDDEGKANYNFTVVASDGA--GNSSEKAITLDITDLDEVAPTIT 1723 Query: 689 SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAEL 748 S I ENS G + + + D + YS+K DD+ F++ + G+ Sbjct: 1724 SASSATAIDENSGAGQVVYTVTSTDSGDIATGATLYSLKAVDDAALFTINSTSGA----- 1778 Query: 749 VTMVDLDYESPRKKYELVIRAASPPLWNDVR-VEILVTDVNDNAPVMKDFQIIFNNYKDC 807 VT+ + + Y + A P N + V + +TD+++ AP + ++ Sbjct: 1779 VTLTANPNDETKADYNFTVVATDSPGNNSEKAVTLDITDLDEIAPTITSAATATAIDENS 1838 Query: 808 FPVGPFGRVPAYDA-DVT-DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATM 865 V + D+ DV Y + +G++A L +N +TG++TL+ + + Sbjct: 1839 GAGQVVYTVTSTDSGDVAIGATVYSLKTGDDAALFTINSSTGAVTLTANPDDETKADYSF 1898 Query: 866 EVSVTD-GVNEIKAMMQLSVRLITE-EMLLNSITVRLNDMTAEQ 907 V TD G N + ++ L + + E ++NS+ + D+ + Sbjct: 1899 IVVATDTGNNSSEQVVTLDINDLDEVAPIINSVVLSDTDLAKSE 1942 Score = 209 bits (511), Expect = 7e-52 Identities = 208/849 (24%), Positives = 359/849 (42%), Gaps = 62/849 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 ++++D +D +P ++ E + +G V T+ +TD D + +Y+++ T D Sbjct: 680 LDIIDLDDVAPTITSASSATALDENSGAGQVVYTVTSTDSDDVSSGSTDYSLK--TGD-- 735 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 DA +F I+ +GA+ A D E A Y V A+D A Sbjct: 736 ---DAA------------LFTINSSTGAVTLSADPDDETKADYNFTVVASDSAGN----- 775 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+ I ++IID ++ P + ++DE+ V+ + +TD+ A A Y+ Sbjct: 776 STEQAITLDIIDLDEVAPTITSTAIAAALDENSGA--GQVVYTVTSTDSGDIATGATAYS 833 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + G+ F+I+S +G+V+L+ D E Y + A D S S + ++I D+ Sbjct: 834 LKIGDDAALFTINSGTGEVTLIANPDDETKADYNFTVVASD--SAGNSTEQAITLDITDL 891 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 +D AP +S+ ++ EN +G + V + D+ + Y++ G+ T Sbjct: 892 DDVAPTITSSVTATAIDENSGVGQVVYTVTSTDSGDIATGVTAYSLK----AGDDAALFT 947 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I+ +G V + D ET+A Y V ATD S+ Sbjct: 948 INSSTGAVTLTANPDDETKADYSFTVVATDTAG--NSSEQVITLDITDLDEVAPTITSAS 1005 Query: 371 YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 L E+ G V T+T+TD+ + Y + + F+I S G +T A P Sbjct: 1006 SATALDENSGAGQVVYTVTSTDSGDIATGATAYSLKTSDDAALFTINSSTGAVTLT-ANP 1064 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 D + Y TV ATD+ G S + ++ITD + AP +A A++ E++ V Sbjct: 1065 -DDEIRADYNFTVVATDTAGNSREQSITLDITDLDEVAPTITSASIAAAIDENSGASQVV 1123 Query: 489 LVVSATDS-DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 V++TD+ D+ A + YSL + ++A F IN TGA+T D E+ + Y Sbjct: 1124 YTVTSTDNGDIATGATV-YSLKA--GDDAAL-----FTINSSTGAVTLTANPDDESKADY 1175 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 TV A D S + + + D++D P + E++ G V V +TD Sbjct: 1176 NFTVVASDAAGNSTEQA--ITLDITDLDDVAPTITSATTATALDENSGAGQVVYTVTSTD 1233 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 + G Y L D + F I+ +SG + D ES A ++ VA DG Sbjct: 1234 SGDIATGVTVYSLKAGD-DAALFTINSSSGAVTLTANPDDESKADYNFTVVASDGAG--N 1290 Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 SS + + I D+++ P S + ENS G + + + D + YS+K Sbjct: 1291 SSEKVTTLDITDLDEVAPTITSASSATALDENSGAGQVVYTVTSTDSGDIATGATAYSLK 1350 Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEIL--VT 785 DD+ F++ + G+ VT+ + + Y + AS N I + Sbjct: 1351 ASDDAALFTINSSTGA-----VTLTANPDDESKADYNFTV-VASDGAGNSTEQAITLDII 1404 Query: 786 DVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD-ADV-TDKLQYRILSGNNANLILLN 843 D++D AP + ++ V + D D+ T Y + +G++A L +N Sbjct: 1405 DLDDVAPTITSASSAIALDENSGAGQVVYTVTSTDNGDIATGATTYSLKAGDDAALFTIN 1464 Query: 844 ETTGSMTLS 852 +TG++TL+ Sbjct: 1465 SSTGAVTLT 1473 Score = 200 bits (487), Expect = 6e-49 Identities = 197/817 (24%), Positives = 346/817 (42%), Gaps = 40/817 (4%) Query: 40 TTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL 99 T+ +T A D++ G +V YT+ + D+ + +F I+ +GA+ Sbjct: 899 TSSVTATAIDENSGVG-QVVYTV--TSTDSGDIATGVTAYSLKAGDDAALFTINSSTGAV 955 Query: 100 LTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSV 159 A+ D E A Y+ V ATD A S+++ I ++I D ++ P + + ++ Sbjct: 956 TLTANPDDETKADYSFTVVATDTAGNSSEQV-----ITLDITDLDEVAPTITSASSATAL 1010 Query: 160 DEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQ 219 DE+ V+ + +TD+ A A Y++ + F+I+S +G V+L D E Sbjct: 1011 DENSGA--GQVVYTVTSTDSGDIATGATAYSLKTSDDAALFTINSSTGAVTLTANPDDEI 1068 Query: 220 VRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRV 279 Y + A D SR + + ++I D+++ AP ++ ++ EN + V Sbjct: 1069 RADYNFTVVATDTAGNSREQS--ITLDITDLDEVAPTITSASIAAAIDENSGASQVVYTV 1126 Query: 280 QAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTAT 339 + D + Y++ G+ TI+ +G V + D E++A Y V A+ Sbjct: 1127 TSTDNGDIATGATVYSLK----AGDDAALFTINSSTGAVTLTANPDDESKADYNFTVVAS 1182 Query: 340 DGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DN 397 D S L E+ G V T+T+TD+ + Sbjct: 1183 DAAG--NSTEQAITLDITDLDDVAPTITSATTATALDENSGAGQVVYTVTSTDSGDIATG 1240 Query: 398 RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQI 457 Y + G+ F+I S +G +T A P D + + Y TV A+D G S + + Sbjct: 1241 VTVYSLKAGDDAALFTINSSSGAVTLT-ANP-DDESKADYNFTVVASDGAGNSSEKVTTL 1298 Query: 458 NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517 +ITD + AP +A ++ E++ G V V++TDS YSL + S++A Sbjct: 1299 DITDLDEVAPTITSASSATALDENSGAGQVVYTVTSTDSGDIATGATAYSLKA--SDDAA 1356 Query: 518 AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577 F IN TGA+T D E+ + Y TV A DG S + + ++D++D Sbjct: 1357 L-----FTINSSTGAVTLTANPDDESKADYNFTVVASDGAGNSTEQA--ITLDIIDLDDV 1409 Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637 P + E++ G V V +TD G Y L D + F I+ ++G Sbjct: 1410 APTITSASSAIALDENSGAGQVVYTVTSTDNGDIATGATTYSLKAGD-DAALFTINSSTG 1468 Query: 638 VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697 + D ES A ++ VA DG SS + + I D+++ P+ S + Sbjct: 1469 AVTLTANPDDESKADYNFTVVASDGAG--NSSEKAITLDITDLDEVGPIITSASSATALD 1526 Query: 698 ENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757 ENS G + + + D + YS+K GDD F++ + G+ + D D E Sbjct: 1527 ENSGAGQVVYTVTSTDNGDIATGATTYSLKSGDDVALFTINSSTGA----VTLTADPDDE 1582 Query: 758 SPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVP 817 S V+ + ++ + + + D+++ AP + I ++ V Sbjct: 1583 SKADYNFTVVASDGAGNSSEKAITLDIIDLDEVAPTITSAAIAAAIDENSGAGQVVYTVM 1642 Query: 818 AYD-ADV-TDKLQYRILSGNNANLILLNETTGSMTLS 852 + D D+ TD Y + SG++A L +N +TG++TL+ Sbjct: 1643 STDNGDIATDATTYSLKSGDDAALFTINSSTGAVTLT 1679 Score = 197 bits (480), Expect = 4e-48 Identities = 205/854 (24%), Positives = 356/854 (41%), Gaps = 46/854 (5%) Query: 34 EGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRID 93 E A + T+ + A D++ G +V YT+ + D+ + +F I+ Sbjct: 996 EVAPTITSASSATALDENSGAG-QVVYTV--TSTDSGDIATGATAYSLKTSDDAALFTIN 1052 Query: 94 GRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEK 153 +GA+ A+ D E A Y V ATD A S +I ++I D ++ P + Sbjct: 1053 SSTGAVTLTANPDDEIRADYNFTVVATDTAGN-----SREQSITLDITDLDEVAPTITSA 1107 Query: 154 TYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVK 213 + ++DE+ + V+ + +TD A A Y++ G+ F+I+S +G V+L Sbjct: 1108 SIAAAIDENSGASQ--VVYTVTSTDNGDIATGATVYSLKAGDDAALFTINSSTGAVTLTA 1165 Query: 214 TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIG 273 D E Y + A D S + ++I D++D AP ++ ++ EN G Sbjct: 1166 NPDDESKADYNFTVVASDAAGNSTEQA--ITLDITDLDDVAPTITSATTATALDENSGAG 1223 Query: 274 YSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQ 333 + V + D+ + Y++ G+ TI+ SG V + D E++A Y Sbjct: 1224 QVVYTVTSTDSGDIATGVTVYSLK----AGDDAALFTINSSSGAVTLTANPDDESKADYN 1279 Query: 334 LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393 V A+DG S+ L E+ G V T+T+TD+ Sbjct: 1280 FTVVASDGAG--NSSEKVTTLDITDLDEVAPTITSASSATALDENSGAGQVVYTVTSTDS 1337 Query: 394 DE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSD 451 + Y + + F+I S G +T A P D + + Y TV A+D G S Sbjct: 1338 GDIATGATAYSLKASDDAALFTINSSTGAVTLT-ANP-DDESKADYNFTVVASDGAGNST 1395 Query: 452 TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE 511 + ++I D ++ AP +A ++ E++ G V V++TD+ TYSL + Sbjct: 1396 EQAITLDIIDLDDVAPTITSASSAIALDENSGAGQVVYTVTSTDNGDIATGATTYSLKA- 1454 Query: 512 ISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571 ++A F IN TGA+T D E+ + Y TV A DG S + + + Sbjct: 1455 -GDDAAL-----FTINSSTGAVTLTANPDDESKADYNFTVVASDGA--GNSSEKAITLDI 1506 Query: 572 VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631 D+++ P+ + E++ G V V +TD G Y L D + F Sbjct: 1507 TDLDEVGPIITSASSATALDENSGAGQVVYTVTSTDNGDIATGATTYSLKSGD-DVALFT 1565 Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC 691 I+ ++G + D ES A ++ VA DG SS + + I D+++ P S Sbjct: 1566 INSSTGAVTLTADPDDESKADYNFTVVASDGAG--NSSEKAITLDIIDLDEVAPTITSAA 1623 Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751 + I ENS G + + + D + YS+K GDD+ F++ + G+ VT+ Sbjct: 1624 IAAAIDENSGAGQVVYTVMSTDNGDIATDATTYSLKSGDDAALFTINSSTGA-----VTL 1678 Query: 752 VDLDYESPRKKYELVIRAASPPLWN--DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFP 809 + + Y + AS N + + + +TD+++ AP + ++ Sbjct: 1679 TANPDDEGKANYNFTV-VASDGAGNSSEKAITLDITDLDEVAPTITSASSATAIDENSGA 1737 Query: 810 VGPFGRVPAYDA-DV-TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEV 867 V + D+ D+ T Y + + ++A L +N T+G++TL+ N V Sbjct: 1738 GQVVYTVTSTDSGDIATGATLYSLKAVDDAALFTINSTSGAVTLTANPNDETKADYNFTV 1797 Query: 868 SVTD--GVNEIKAM 879 TD G N KA+ Sbjct: 1798 VATDSPGNNSEKAV 1811 Score = 196 bits (478), Expect = 7e-48 Identities = 184/770 (23%), Positives = 329/770 (42%), Gaps = 41/770 (5%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +F I+ +G ++ A+ D E A Y + A+D A +S++ ++ +I D ++ P Sbjct: 533 LFAINSSTGTVILTANPDYESKADYNFTLVASDPAGNISEQ-----SVTFDITDLDEVAP 587 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 + + ++DE+ V+ + +TD+ A Y++ G+ F+I+S +G Sbjct: 588 TITSASTASTIDENSG--SGQVVYTVTSTDSSDITTGATSYSLKAGDDAALFNINSSTGA 645 Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268 V+L D E Y + A D SR + ++I D++D AP ++ ++ E Sbjct: 646 VTLTADPDDETKADYNFTVLASDAAGNSREQA--ITLDIIDLDDVAPTITSASSATALDE 703 Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328 N G + V + D+D+ + Y++ TG+ TI+ +G V S D ET Sbjct: 704 NSGAGQVVYTVTSTDSDDVSSGSTDYSLK----TGDDAALFTINSSTGAVTLSADPDDET 759 Query: 329 QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388 +A Y V A+D S L E+ G V T+ Sbjct: 760 KADYNFTVVASDSAG--NSTEQAITLDIIDLDEVAPTITSTAIAAALDENSGAGQVVYTV 817 Query: 389 TATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446 T+TD+ + Y + G+ F+I S G G +T+ D + + Y TV A+DS Sbjct: 818 TSTDSGDIATGATAYSLKIGDDAALFTINS--GTGEVTLIANPDDETKADYNFTVVASDS 875 Query: 447 GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506 G S + ++ITD ++ AP ++ ++ E++ +G V V++TDS Y Sbjct: 876 AGNSTEQAITLDITDLDDVAPTITSSVTATAIDENSGVGQVVYTVTSTDSGDIATGVTAY 935 Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566 SL + ++A F IN TGA+T D ET + Y TV A D S Sbjct: 936 SLKA--GDDAAL-----FTINSSTGAVTLTANPDDETKADYSFTVVATD--TAGNSSEQV 986 Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE 626 + + + D+++ P + E++ G V V +TD+ G Y L D + Sbjct: 987 ITLDITDLDEVAPTITSASSATALDENSGAGQVVYTVTSTDSGDIATGATAYSLKTSD-D 1045 Query: 627 EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686 F I+ ++G + D E A ++ VA D T S + + I D+++ P Sbjct: 1046 AALFTINSSTGAVTLTANPDDEIRADYNFTVVATD--TAGNSREQSITLDITDLDEVAPT 1103 Query: 687 FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746 S + I ENS + + + D + YS+K GDD+ F++ + G+ Sbjct: 1104 ITSASIAAAIDENSGASQVVYTVTSTDNGDIATGATVYSLKAGDDAALFTINSSTGA--- 1160 Query: 747 ELVTMVDLDYESPRKKYELVIRAASPPLWNDVR--VEILVTDVNDNAPVMKDFQIIFNNY 804 VT+ + + Y + AS N + + +TD++D AP + Sbjct: 1161 --VTLTANPDDESKADYNFTV-VASDAAGNSTEQAITLDITDLDDVAPTITSATTATALD 1217 Query: 805 KDCFPVGPFGRVPAYDA-DV-TDKLQYRILSGNNANLILLNETTGSMTLS 852 ++ V + D+ D+ T Y + +G++A L +N ++G++TL+ Sbjct: 1218 ENSGAGQVVYTVTSTDSGDIATGVTVYSLKAGDDAALFTINSSSGAVTLT 1267 Score = 175 bits (425), Expect = 2e-41 Identities = 164/671 (24%), Positives = 285/671 (42%), Gaps = 35/671 (5%) Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD-GGSPSRSNTTQLLIN 246 R+++ G + + F+I+S +G V L DYE Y + A D G+ S + T + Sbjct: 523 RFSLTGDDASL-FAINSSTGTVILTANPDYESKADYNFTLVASDPAGNISEQSVT---FD 578 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 I D+++ AP ++ ++ EN G + V + D+ + +Y++ G+ Sbjct: 579 ITDLDEVAPTITSASTASTIDENSGSGQVVYTVTSTDSSDITTGATSYSLK----AGDDA 634 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 I+ +G V + D ET+A Y V A+D R T Sbjct: 635 ALFNINSSTGAVTLTADPDDETKADYNFTVLASDAAGNSREQAIT--LDIIDLDDVAPTI 692 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLIT 424 L E+ G V T+T+TD+D+ Y + G+ F+I S G +T Sbjct: 693 TSASSATALDENSGAGQVVYTVTSTDSDDVSSGSTDYSLKTGDDAALFTINSST--GAVT 750 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 ++ D + + Y TV A+DS G S + ++I D + AP + A++ E++ Sbjct: 751 LSADPDDETKADYNFTVVASDSAGNSTEQAITLDIIDLDEVAPTITSTAIAAALDENSGA 810 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 G V V++TDS YSL +I ++A F IN TG +T D ET Sbjct: 811 GQVVYTVTSTDSGDIATGATAYSL--KIGDDAAL-----FTINSGTGEVTLIANPDDETK 863 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 + Y TV A D S + + + D++D P + I E++ VG V V Sbjct: 864 ADYNFTVVASDSAGNSTEQA--ITLDITDLDDVAPTITSSVTATAIDENSGVGQVVYTVT 921 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 +TD+ G Y L D + F I+ ++G + D E+ A + VA D T Sbjct: 922 STDSGDIATGVTAYSLKAGD-DAALFTINSSTGAVTLTANPDDETKADYSFTVVATD--T 978 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 SS ++ + I D+++ P S + ENS G + + + D + Y Sbjct: 979 AGNSSEQVITLDITDLDEVAPTITSASSATALDENSGAGQVVYTVTSTDSGDIATGATAY 1038 Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL-VIRAASPPLWNDVRVEIL 783 S+K DD+ F++ + G+ VT+ + R Y V+ + + + + Sbjct: 1039 SLKTSDDAALFTINSSTGA-----VTLTANPDDEIRADYNFTVVATDTAGNSREQSITLD 1093 Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD-ADV-TDKLQYRILSGNNANLIL 841 +TD+++ AP + I ++ V + D D+ T Y + +G++A L Sbjct: 1094 ITDLDEVAPTITSASIAAAIDENSGASQVVYTVTSTDNGDIATGATVYSLKAGDDAALFT 1153 Query: 842 LNETTGSMTLS 852 +N +TG++TL+ Sbjct: 1154 INSSTGAVTLT 1164 Score = 141 bits (342), Expect = 2e-31 Identities = 137/575 (23%), Positives = 242/575 (42%), Gaps = 26/575 (4%) Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 TG+ I+ +G V + D E++A Y + A+D + T Sbjct: 527 TGDDASLFAINSSTGTVILTANPDYESKADYNFTLVASDPAGNISEQSVTFDITDLDEVA 586 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNG 419 ++ E+ G V T+T+TD+ + Y + G+ F+I S G Sbjct: 587 PTITSASTASTID--ENSGSGQVVYTVTSTDSSDITTGATSYSLKAGDDAALFNINSSTG 644 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479 +T A P D + + Y TV A+D+ G S + ++I D ++ AP +A ++ Sbjct: 645 AVTLT-ADP-DDETKADYNFTVLASDAAGNSREQAITLDIIDLDDVAPTITSASSATALD 702 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E++ G V V++TDSD + YSL + ++A F IN TGA+T + Sbjct: 703 ENSGAGQVVYTVTSTDSDDVSSGSTDYSLKT--GDDAAL-----FTINSSTGAVTLSADP 755 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 D ET + Y TV A D S + + ++D+++ P A + E++ G Sbjct: 756 DDETKADYNFTVVASDSAGNSTEQA--ITLDIIDLDEVAPTITSTAIAAALDENSGAGQV 813 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 V V +TD+ G Y L D + F I+ +G + D E+ A ++ VA Sbjct: 814 VYTVTSTDSGDIATGATAYSLKIGD-DAALFTINSGTGEVTLIANPDDETKADYNFTVVA 872 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 D S+ + + I D++D P S I ENS +G + + + D + Sbjct: 873 SDSAG--NSTEQAITLDITDLDDVAPTITSSVTATAIDENSGVGQVVYTVTSTDSGDIAT 930 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVR 779 V YS+K GDD+ F++ + G+ VT+ + + Y + A + + Sbjct: 931 GVTAYSLKAGDDAALFTINSSTGA-----VTLTANPDDETKADYSFTVVATDTAGNSSEQ 985 Query: 780 VEIL-VTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDA-DV-TDKLQYRILSGNN 836 V L +TD+++ AP + ++ V + D+ D+ T Y + + ++ Sbjct: 986 VITLDITDLDEVAPTITSASSATALDENSGAGQVVYTVTSTDSGDIATGATAYSLKTSDD 1045 Query: 837 ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 A L +N +TG++TL+ + + V TD Sbjct: 1046 AALFTINSSTGAVTLTANPDDEIRADYNFTVVATD 1080 Score = 139 bits (336), Expect = 1e-30 Identities = 127/497 (25%), Positives = 222/497 (44%), Gaps = 25/497 (5%) Query: 378 DEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437 DE GT V A DE+ R + +TG + F+I S G ++T A P D++ + Y Sbjct: 503 DENSGTHQVVYQAVTNDENAR--FSLTGDDA-SLFAINSSTGTVILT-ANP-DYESKADY 557 Query: 438 VLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497 T+ A+D G V +ITD + AP +A +++ E++ G V V++TDS Sbjct: 558 NFTLVASDPAGNISEQSVTFDITDLDEVAPTITSASTASTIDENSGSGQVVYTVTSTDSS 617 Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG 557 +YSL + ++A F IN TGA+T D ET + Y TV A D Sbjct: 618 DITTGATSYSLKA--GDDAAL-----FNINSSTGAVTLTADPDDETKADYNFTVLASDAA 670 Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIH 617 S + + ++D++D P + E++ G V V +TD+D +G Sbjct: 671 GNSREQA--ITLDIIDLDDVAPTITSASSATALDENSGAGQVVYTVTSTDSDDVSSGSTD 728 Query: 618 YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 Y L D + F I+ ++G + + D E+ A ++ VA D S+ + + I Sbjct: 729 YSLKTGD-DAALFTINSSTGAVTLSADPDDETKADYNFTVVASDSAG--NSTEQAITLDI 785 Query: 678 EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL 737 D+++ P S + + ENS G + + + D + YS+K GDD+ F++ Sbjct: 786 IDLDEVAPTITSTAIAAALDENSGAGQVVYTVTSTDSGDIATGATAYSLKIGDDAALFTI 845 Query: 738 ETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDF 797 + G E+ + + D E+ V+ + S + + + +TD++D AP + Sbjct: 846 NSGTG----EVTLIANPDDETKADYNFTVVASDSAGNSTEQAITLDITDLDDVAPTITS- 900 Query: 798 QIIFNNYKDCFPVGPFG-RVPAYDA-DV-TDKLQYRILSGNNANLILLNETTGSMTLSPQ 854 + + VG V + D+ D+ T Y + +G++A L +N +TG++TL+ Sbjct: 901 SVTATAIDENSGVGQVVYTVTSTDSGDIATGVTAYSLKAGDDAALFTINSSTGAVTLTAN 960 Query: 855 LNTNVPKLATMEVSVTD 871 + + V TD Sbjct: 961 PDDETKADYSFTVVATD 977 >UniRef50_Q4S0C3 Cluster: Chromosome 2 SCAF14781, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 2 SCAF14781, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 881 Score = 209 bits (510), Expect = 1e-51 Identities = 175/581 (30%), Positives = 268/581 (46%), Gaps = 38/581 (6%) Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDG-GSPSRSNTTQLLI 245 + ++ N + + G +S+ +D EQ+ RS R +I + + + I Sbjct: 59 FRLMQENNSSVIQMREVDGLLSVADVIDREQLCPRSLRCLITFDIVVRAKEKFQLIHVEI 118 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 ++D+ND+ PRF + + ENVP+G A D D G N +Y ++ + V Sbjct: 119 EVKDINDHPPRFPHNETHLEIVENVPLGSRFPLEIALDQDVGENYIQSYNISPSSHF-EV 177 Query: 306 DLPITIDP-RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 ++ D + + +LDRE + Y + VTATDGG RS + Sbjct: 178 EVRDQEDGLKFAELVLVRELDREVEDSYTIKVTATDGGVHARSGSMLVNIKVLDSNDNSP 237 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTR--GR-FSITSQNG 419 F VEL ED P G V+ + A D DE + + Y + G + GR F + G Sbjct: 238 SFEHSSLTVELDEDSPVGHRVLRVHAFDPDEGVNGEVTYALAAGFSPEVGRLFHVDPYTG 297 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYT-- 475 +T+ +DF++ R Y L + A+D G S T V I++ D N+ AP P T Sbjct: 298 E--VTLKGLVDFERRRLYELVIKASDMGANSVPSTCKVHIDVVDVNDNAPEISIKPMTPG 355 Query: 476 ----ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 AS+ E A + V ++S +D D G N + SL + +E H Q Sbjct: 356 SDGVASITEAAAADSFVALISTSDRDSGSNGYVRVSL---LGHE---HFSLQQAYGDSFM 409 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 ITT LDRE + Y LTV A D G P + V D NDN P+F + LY +++ Sbjct: 410 IITTT-ALDRERIPEYNLTVVAEDLGNPPFKTVRQYTVRVKDENDNPPLFSKTLYEVSVL 468 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV-----IDPASGVIRTNKALD 646 E+ + G+ V+ V A D DVG N ++ Y++ + GS V +D SG + T ++ D Sbjct: 469 ENNIPGSYVTTVVARDPDVGENAKVSYKVLDAEVPGGSPVSTYVSVDSHSGSLYTLRSFD 528 Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS-P----PVFESDCLTFYISENSP 701 E++ DL A D G+P SST + IK+ D ND+ P PV ++D + N+P Sbjct: 529 YETLQQIDLVIQAEDRGSPSLSSTSTIRIKVVDQNDNYPYFTFPVLQNDSADVPLPFNAP 588 Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 G + A D DEG N V+ + I G D+N F ++ G Sbjct: 589 AGYLALRVSAEDEDEGMNKVLSFQIFQG-DTNLFRVDKDSG 628 Score = 204 bits (499), Expect = 2e-50 Identities = 151/473 (31%), Positives = 236/473 (49%), Gaps = 35/473 (7%) Query: 423 ITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 + + + LD + E Y + V+ATD G RS + +V I + D+N+ +P FE++ T + E Sbjct: 191 LVLVRELDREVEDSYTIKVTATDGGVHARSGSMLVNIKVLDSNDNSPSFEHSSLTVELDE 250 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 D+P+G VL V A D D G+N ++TY+L++ S E + F ++P TG +T L+D Sbjct: 251 DSPVGHRVLRVHAFDPDEGVNGEVTYALAAGFSPEV----GRLFHVDPYTGEVTLKGLVD 306 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT------ANIMEDA 594 E Y L + A D G S+ T V I VVDVNDN P + T A+I E A Sbjct: 307 FERRRLYELVIKASDMGANSVPSTCKVHIDVVDVNDNAPEISIKPMTPGSDGVASITEAA 366 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG---VIRTNKALDRESVA 651 + V+ + +D D G NG + L + F + A G +I T ALDRE + Sbjct: 367 AADSFVALISTSDRDSGSNGYVRVSLLGHEH----FSLQQAYGDSFMIITTTALDRERIP 422 Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRA 711 ++L VA D G PP + ++++D ND+PP+F + EN+ G+ + + A Sbjct: 423 EYNLTVVAEDLGNPPFKTVRQYTVRVKDENDNPPLFSKTLYEVSVLENNIPGSYVTTVVA 482 Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK--AELVTMVDLDYESPRKKYELVIRA 769 DPD G NA V Y + + + T D L T+ DYE+ ++ +LVI+A Sbjct: 483 RDPDVGENAKVSYKVLDAEVPGGSPVSTYVSVDSHSGSLYTLRSFDYET-LQQIDLVIQA 541 Query: 770 ---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC-FPV-GPFG----RVPAYD 820 SP L + + I V D NDN P F ++ N+ D P P G RV A D Sbjct: 542 EDRGSPSLSSTSTIRIKVVDQNDNYPYF-TFPVLQNDSADVPLPFNAPAGYLALRVSAED 600 Query: 821 AD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 D + L ++I G + NL +++ +G + L L+ + + +++SV+D Sbjct: 601 EDEGMNKVLSFQIFQG-DTNLFRVDKDSGEIVLKQWLSAEIGDVLEIKISVSD 652 Score = 187 bits (456), Expect = 3e-45 Identities = 155/566 (27%), Positives = 247/566 (43%), Gaps = 25/566 (4%) Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN 195 + + + D ND+ P+F + + E++ + + A D DVG N Y I + Sbjct: 116 VEIEVKDINDHPPRFPHNETHLEIVENVPLGSRFPLEI--ALDQDVGENYIQSYNISPSS 173 Query: 196 ---TQMQFSIDSLS-GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251 +++ D L ++ LV+ LD E SY + + A DGG +RS + + I + D N Sbjct: 174 HFEVEVRDQEDGLKFAELVLVRELDREVEDSYTIKVTATDGGVHARSGSMLVNIKVLDSN 233 Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311 DN+P F S + E+ P+G+ ++RV A+D DEGVN E+TY + ++ V + Sbjct: 234 DNSPSFEHSSLTVELDEDSPVGHRVLRVHAFDPDEGVNGEVTYALA-AGFSPEVGRLFHV 292 Query: 312 DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA-----TXXXXXXXXXXXXXXF 366 DP +G V G +D E + Y+L++ A+D G +T Sbjct: 293 DPYTGEVTLKGLVDFERRRLYELVIKASDMGANSVPSTCKVHIDVVDVNDNAPEISIKPM 352 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG-LITV 425 PG V + V L +T + Y FS+ G +I Sbjct: 353 TPGSDGVASITEAAAADSFVALISTSDRDSGSNGYVRVSLLGHEHFSLQQAYGDSFMIIT 412 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAMVQ--INITDANNYAPVFENAPYTASVFEDAP 483 LD ++ Y LTV A D G + Q + + D N+ P+F Y SV E+ Sbjct: 413 TTALDRERIPEYNLTVVAEDLGNPPFKTVRQYTVRVKDENDNPPLFSKTLYEVSVLENNI 472 Query: 484 IGTTVLVVSATDSDVGINAQITYS-LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 G+ V V A D DVG NA+++Y L +E+ + ++ +G++ T + D E Sbjct: 473 PGSYVTTVVARDPDVGENAKVSYKVLDAEVPGGSPV--STYVSVDSHSGSLYTLRSFDYE 530 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME-----DALVG 597 T+ L + A D G PSLS T+ + I VVD NDN P F + + + +A G Sbjct: 531 TLQQIDLVIQAEDRGSPSLSSTSTIRIKVVDQNDNYPYFTFPVLQNDSADVPLPFNAPAG 590 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 +V A D D G+N + +++ D F +D SG I + L E ++K Sbjct: 591 YLALRVSAEDEDEGMNKVLSFQIFQGD--TNLFRVDKDSGEIVLKQWLSAEIGDVLEIKI 648 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDS 683 D G P SS+ + + D S Sbjct: 649 SVSDNGRSPLSSSATIRFLVSDTEPS 674 Score = 175 bits (427), Expect = 1e-41 Identities = 163/591 (27%), Positives = 254/591 (42%), Gaps = 58/591 (9%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 IH +I V D NDH P F + + E G+ A DQD+G+N Y I Sbjct: 114 IHVEIEVKDINDHPPRFPHNETHLEIVENVPLGSRFPLEIALDQDVGENYIQSYNI---- 169 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGA-LLTRASLDREKVARYTVLVKATDQASP 125 +P V+D + DG A L+ LDRE YT+ V ATD Sbjct: 170 ----SPSS------HFEVEVRD--QEDGLKFAELVLVRELDREVEDSYTIKVTATDGG-- 215 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 V R S + +++ ++D NDN P F + TV +DED V + ++ A D D G N Sbjct: 216 VHAR-SGSMLVNIKVLDSNDNSPSFEHSSLTVELDEDSPVGHR--VLRVHAFDPDEGVNG 272 Query: 186 AIRYAIIGG---NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 + YA+ G F +D +G+V+L +D+E+ R Y LVI+A D G+ S +T + Sbjct: 273 EVTYALAAGFSPEVGRLFHVDPYTGEVTLKGLVDFERRRLYELVIKASDMGANSVPSTCK 332 Query: 243 LLINIRDVNDNAPRFYTSLFQ------ESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 + I++ DVNDNAP S++E + + D D G N + ++ Sbjct: 333 VHIDVVDVNDNAPEISIKPMTPGSDGVASITEAAAADSFVALISTSDRDSGSNGYVRVSL 392 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 ++ L S + T+ LDRE +Y L V A D G+PP Sbjct: 393 LGHEH---FSLQQAYGD-SFMIITTTALDRERIPEYNLTVVAEDLGNPPFKTVRQYTVRV 448 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHY-----EITGGNTR 409 F YEV + E+ PG+ V T+ A D D E+ ++ Y E+ GG+ Sbjct: 449 KDENDNPPLFSKTLYEVSVLENNIPGSYVTTVVARDPDVGENAKVSYKVLDAEVPGGSPV 508 Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDAN-NYA 466 + + L T+ + D++ ++ L + A D G S T+ ++I + D N NY Sbjct: 509 STYVSVDSHSGSLYTL-RSFDYETLQQIDLVIQAEDRGSPSLSSTSTIRIKVVDQNDNYP 567 Query: 467 ----PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522 PV +N + +AP G L VSA D D G+N +++ + +N Sbjct: 568 YFTFPVLQNDSADVPLPFNAPAGYLALRVSAEDEDEGMNKVLSFQIFQGDTN-------- 619 Query: 523 QFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 F ++ +G I + L E + ++ D G LS + + V D Sbjct: 620 LFRVDKDSGEIVLKQWLSAEIGDVLEIKISVSDNGRSPLSSSATIRFLVSD 670 Score = 142 bits (345), Expect = 9e-32 Identities = 126/430 (29%), Positives = 195/430 (45%), Gaps = 26/430 (6%) Query: 421 GLITVAQPLDFKQ----ERRYVLTVS-ATDSGGRSDTAMVQINITDANNYAPVFENAPYT 475 GL++VA +D +Q R ++T + + V+I + D N++ P F + Sbjct: 77 GLLSVADVIDREQLCPRSLRCLITFDIVVRAKEKFQLIHVEIEVKDINDHPPRFPHNETH 136 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 + E+ P+G+ + A D DVG N +Y++S S+ V DQ+ + + + Sbjct: 137 LEIVENVPLGSRFPLEIALDQDVGENYIQSYNISPS-SHFEVEVRDQEDGL--KFAELVL 193 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 + LDRE Y + VTA DGGV + S + V I V+D NDN P F+ T + ED+ Sbjct: 194 VRELDREVEDSYTIKVTATDGGVHARSGSMLVNIKVLDSNDNSPSFEHSSLTVELDEDSP 253 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGS--FVIDPASGVIRTNKALDRESVATH 653 VG V +V A D D G+NG + Y L E F +DP +G + +D E + Sbjct: 254 VGHRVLRVHAFDPDEGVNGEVTYALAAGFSPEVGRLFHVDPYTGEVTLKGLVDFERRRLY 313 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT------FYISENSPIGTTIG 707 +L A D G ST VHI + D+ND+ P +T I+E + + + Sbjct: 314 ELVIKASDMGANSVPSTCKVHIDVVDVNDNAPEISIKPMTPGSDGVASITEAAAADSFVA 373 Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 I D D G N V S+ G + FSL+ G D ++T LD E +Y L + Sbjct: 374 LISTSDRDSGSNGYVRVSLLGHE---HFSLQQAYG-DSFMIITTTALDRER-IPEYNLTV 428 Query: 768 RA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVT 824 A +PP + + V D NDN P+ + ++ P V A D DV Sbjct: 429 VAEDLGNPPFKTVRQYTVRVKDENDNPPLFSKTLYEVSVLENNIPGSYVTTVVARDPDVG 488 Query: 825 D--KLQYRIL 832 + K+ Y++L Sbjct: 489 ENAKVSYKVL 498 Score = 104 bits (249), Expect = 4e-20 Identities = 72/254 (28%), Positives = 117/254 (46%), Gaps = 20/254 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D ND+ P+F YE SV E G+ V T+ A D D+G+NA+V Y + Sbjct: 446 VRVKDENDNPPLFSKTLYEVSVLENNIPGSYVTTVVARDPDVGENAKVSYKVLDAEVPGG 505 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +P V +D SG+L T S D E + + ++++A D+ SP L Sbjct: 506 SP-------------VSTYVSVDSHSGSLYTLRSFDYETLQQIDLVIQAEDRGSP---SL 549 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTY---TVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 SST+TI + ++D NDNYP F+ + V + + ++ A D D G N + Sbjct: 550 SSTSTIRIKVVDQNDNYPYFTFPVLQNDSADVPLPFNAPAGYLALRVSAEDEDEGMNKVL 609 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 + I G+T + F +D SG++ L + L E + I D G S++ + + Sbjct: 610 SFQIFQGDTNL-FRVDKDSGEIVLKQWLSAEIGDVLEIKISVSDNGRSPLSSSATIRFLV 668 Query: 248 RDVNDNAPRFYTSL 261 D +A + + L Sbjct: 669 SDTEPSADQVFLVL 682 >UniRef50_UPI000069E7C3 Cluster: Protocadherin beta 11 precursor (PCDH-beta11).; n=9; Xenopus tropicalis|Rep: Protocadherin beta 11 precursor (PCDH-beta11). - Xenopus tropicalis Length = 795 Score = 206 bits (504), Expect = 5e-51 Identities = 163/564 (28%), Positives = 263/564 (46%), Gaps = 34/564 (6%) Query: 135 TIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG 194 +I V I D NDN P F + + + + E S A D D+G NS Y + Sbjct: 119 SIKVEIQDINDNAPSFPKNSLKIVISE--SALPGVRFGLGYAQDPDLGINSVQSYGLSTN 176 Query: 195 NTQMQFSIDSLSG----DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + + S G ++ L K+LD EQ S L + A DGG P ++ TT + I + D Sbjct: 177 DYFILGERTSSDGSKYPELVLEKSLDREQQSSIELSLSASDGGRPMKTGTTLIRIVVYDA 236 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPIT 310 NDN P F +Q ++ ENV +S++++QA D DEG N ++TY+ T N + Sbjct: 237 NDNHPVFSQDNYQVNIYENVANNFSVLQIQATDIDEGANGQITYSFT--HIPENALHIFS 294 Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 ID ++G + G LD E KY L V A DGG+ + Sbjct: 295 IDSQTGQITKIGDLDYEVTKKYTLTVEAKDGGELVSHCKVSIQVIDANDNAPEIQI--NS 352 Query: 371 YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 + + ED PP T + + D D E+ + +I N + +++ L+T+++ Sbjct: 353 FLGTVPEDSPPETVIAIIYVHDLDSGENGEVVCQIP-ENLPFQLITLTESYYKLVTLSR- 410 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGT 486 +D ++ Y ++++A D G S +++ +++ +TD N+ PVFE Y V E+ G Sbjct: 411 MDRERTSEYNISITAKDKGTPSLSSLKTIRVALTDVNDNIPVFEKTHYVTYVPENNQPGM 470 Query: 487 TVLVVSATDSDVGINAQITYS-LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 ++L V+A D D+ N ITYS +S+ I N ++ H IN TG I D E + Sbjct: 471 SILHVNALDFDINDNGFITYSVISTAIQNIPISSH---VSINSATGVIYALHAFDYEQIR 527 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV--------- 596 + V A D G PSLS + + + ++D NDN P + LY ++ E + Sbjct: 528 EFQFQVMATDNGSPSLSSNSTIRVCIIDKNDNAP---EILYPSSDTEGTALYEFIPHSSD 584 Query: 597 -GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDL 655 G V++V A DAD G N + Y L + +E F I ++G IR + + + Sbjct: 585 RGYLVTKVIAVDADSGHNAWLSYHL-LQAQEPSVFTIGQSTGEIRLARGFQETDSSRQKV 643 Query: 656 KAVAIDGGTPPQSSTVIVHIKIED 679 + D G P S+TV +++ I + Sbjct: 644 VVMVKDNGEPTLSATVTLNLIIAE 667 Score = 174 bits (423), Expect = 3e-41 Identities = 155/582 (26%), Positives = 251/582 (43%), Gaps = 53/582 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ + D ND++P F + + E A G A D D+G N+ Y + Sbjct: 121 KVEIQDINDNAPSFPKNSLKIVISESALPGVRFGLGYAQDPDLGINSVQSYGLSTNDYFI 180 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 L + DG + L+ SLDRE+ + + + A+D P+ Sbjct: 181 LGERTSS----------------DGSKYPELVLEKSLDREQQSSIELSLSASDGGRPMK- 223 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 + T I + + D NDN+P FS+ Y V++ E +V +N + +I+ATD D GAN I Sbjct: 224 --TGTTLIRIVVYDANDNHPVFSQDNYQVNIYE--NVANNFSVLQIQATDIDEGANGQIT 279 Query: 189 YAI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 Y+ I N FSIDS +G ++ + LDYE + Y L + A+DGG + ++ I Sbjct: 280 YSFTHIPENALHIFSIDSQTGQITKIGDLDYEVTKKYTLTVEAKDGG--ELVSHCKVSIQ 337 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + D NDNAP + F +V E+ P I + +D D G N E+ + + N+ Sbjct: 338 VIDANDNAPEIQINSFLGTVPEDSPPETVIAIIYVHDLDSGENGEVVCQIPE-----NLP 392 Query: 307 LP-ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 IT+ + T ++DRE ++Y + +TA D G P S+ T Sbjct: 393 FQLITLTESYYKLVTLSRMDRERTSEYNISITAKDKGTPSLSSLKTIRVALTDVNDNIPV 452 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDAD-EDNR-LHYEITG---GNTRGRFSITSQNGR 420 F Y + E+ PG ++ + A D D DN + Y + N ++ + Sbjct: 453 FEKTHYVTYVPENNQPGMSILHVNALDFDINDNGFITYSVISTAIQNIPISSHVSINSAT 512 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVF---ENAPYT 475 G+I D++Q R + V ATD+G S + +++ I D N+ AP + Sbjct: 513 GVIYALHAFDYEQIREFQFQVMATDNGSPSLSSNSTIRVCIIDKNDNAPEILYPSSDTEG 572 Query: 476 ASVFEDAP----IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 +++E P G V V A D+D G NA ++Y L A F I TG Sbjct: 573 TALYEFIPHSSDRGYLVTKVIAVDADSGHNAWLSYHLLQ-------AQEPSVFTIGQSTG 625 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 I + S + V +D G P+LS T + + + + Sbjct: 626 EIRLARGFQETDSSRQKVVVMVKDNGEPTLSATVTLNLIIAE 667 Score = 166 bits (404), Expect = 7e-39 Identities = 116/376 (30%), Positives = 183/376 (48%), Gaps = 15/376 (3%) Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480 + + + LD +Q+ L++SA+D G ++ T +++I + DAN+ PVF Y +++E Sbjct: 195 LVLEKSLDREQQSSIELSLSASDGGRPMKTGTTLIRIVVYDANDNHPVFSQDNYQVNIYE 254 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 + +VL + ATD D G N QITYS + N A H F I+ QTG IT LD Sbjct: 255 NVANNFSVLQIQATDIDEGANGQITYSFTHIPEN---ALHI--FSIDSQTGQITKIGDLD 309 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 E Y LTV A+DGG L V I V+D NDN P + + + ED+ T + Sbjct: 310 YEVTKKYTLTVEAKDGG--ELVSHCKVSIQVIDANDNAPEIQINSFLGTVPEDSPPETVI 367 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 + + D D G NG + ++ P++ + + + T +DRE + +++ A Sbjct: 368 AIIYVHDLDSGENGEVVCQI-PENLPFQLITLTESYYKLVTLSRMDRERTSEYNISITAK 426 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 D GTP SS + + + D+ND+ PVFE Y+ EN+ G +I + A D D N Sbjct: 427 DKGTPSLSSLKTIRVALTDVNDNIPVFEKTHYVTYVPENNQPGMSILHVNALDFDINDNG 486 Query: 721 VVHYSIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN 776 + YS+ N S S + + DYE R +++ + A SP L + Sbjct: 487 FITYSVISTAIQNIPISSHVSINSATGVIYALHAFDYEQIR-EFQFQVMATDNGSPSLSS 545 Query: 777 DVRVEILVTDVNDNAP 792 + + + + D NDNAP Sbjct: 546 NSTIRVCIIDKNDNAP 561 Score = 145 bits (351), Expect = 2e-32 Identities = 126/404 (31%), Positives = 182/404 (45%), Gaps = 21/404 (5%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 +++ I D N+ AP F + E A G + A D D+GIN+ +Y LS+ N Sbjct: 120 IKVEIQDINDNAPSFPKNSLKIVISESALPGVRFGLGYAQDPDLGINSVQSYGLST---N 176 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 + ++ + + K LDRE S L+++A DGG P + TT + I V D Sbjct: 177 DYFILGERTSSDGSKYPELVLEKSLDREQQSSIELSLSASDGGRPMKTGTTLIRIVVYDA 236 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP-KDREEGSFVID 633 NDN PVF Q Y NI E+ SV Q+ ATD D G NG+I Y + F ID Sbjct: 237 NDNHPVFSQDNYQVNIYENVANNFSVLQIQATDIDEGANGQITYSFTHIPENALHIFSID 296 Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693 +G I LD E + L A DGG S V I++ D ND+ P + + Sbjct: 297 SQTGQITKIGDLDYEVTKKYTLTVEAKDGGE--LVSHCKVSIQVIDANDNAPEIQINSFL 354 Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753 + E+SP T I I HD D G N V I ++ F L T S +LVT+ Sbjct: 355 GTVPEDSPPETVIAIIYVHDLDSGENGEVVCQIP---ENLPFQLITLTES-YYKLVTLSR 410 Query: 754 LDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV 810 +D E +Y + I A +P L + + + +TDVNDN PV + + ++ P Sbjct: 411 MDRERT-SEYNISITAKDKGTPSLSSLKTIRVALTDVNDNIPVFEKTHYVTYVPENNQPG 469 Query: 811 GPFGRVPAYDADVTDK--LQYRILSGNNANL-----ILLNETTG 847 V A D D+ D + Y ++S N+ + +N TG Sbjct: 470 MSILHVNALDFDINDNGFITYSVISTAIQNIPISSHVSINSATG 513 Score = 114 bits (274), Expect = 4e-23 Identities = 88/290 (30%), Positives = 138/290 (47%), Gaps = 14/290 (4%) Query: 512 ISNEAVAHHDQ-QFV-INPQTGAITTNKLLDRETMSGY-LLTVTARDGGVPSLSDTTDVE 568 + N +A HD+ Q+V +N + G + + +DRE + G + + + ++ Sbjct: 62 LRNLHIASHDKKQYVNVNLENGDLVITEKIDREALCGTEQQCILNLKAMIENPLQIFSIK 121 Query: 569 ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE- 627 + + D+NDN P F + I E AL G A D D+G+N Y L D Sbjct: 122 VEIQDINDNAPSFPKNSLKIVISESALPGVRFGLGYAQDPDLGINSVQSYGLSTNDYFIL 181 Query: 628 GSFVIDPASGV--IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685 G S + K+LDRE ++ +L A DGG P ++ T ++ I + D ND+ P Sbjct: 182 GERTSSDGSKYPELVLEKSLDREQQSSIELSLSASDGGRPMKTGTTLIRIVVYDANDNHP 241 Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS--NSFSLETRQGS 743 VF D I EN ++ +I+A D DEG N + YS ++ + FS++++ G Sbjct: 242 VFSQDNYQVNIYENVANNFSVLQIQATDIDEGANGQITYSFTHIPENALHIFSIDSQTG- 300 Query: 744 DKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAP 792 ++ + DLDYE KKY L + A L + +V I V D NDNAP Sbjct: 301 ---QITKIGDLDYE-VTKKYTLTVEAKDGGELVSHCKVSIQVIDANDNAP 346 Score = 74.9 bits (176), Expect = 3e-11 Identities = 63/223 (28%), Positives = 102/223 (45%), Gaps = 11/223 (4%) Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732 + ++I+DIND+ P F + L ISE++ G G A DPD G N+V Y + D Sbjct: 120 IKVEIQDINDNAPSFPKNSLKIVISESALPGVRFGLGYAQDPDLGINSVQSYGLSTNDYF 179 Query: 733 NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVND 789 + GS ELV LD E + EL + A+ P + I+V D ND Sbjct: 180 ILGERTSSDGSKYPELVLEKSLDREQ-QSSIELSLSASDGGRPMKTGTTLIRIVVYDAND 238 Query: 790 NAPVMK--DFQI-IFNNYKDCFPVGPFGRVPAYDADVTDKLQYRI--LSGNNANLILLNE 844 N PV ++Q+ I+ N + F V + D ++ Y + N ++ ++ Sbjct: 239 NHPVFSQDNYQVNIYENVANNFSVLQI-QATDIDEGANGQITYSFTHIPENALHIFSIDS 297 Query: 845 TTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887 TG +T L+ V K T+ V DG E+ + ++S+++I Sbjct: 298 QTGQITKIGDLDYEVTKKYTLTVEAKDG-GELVSHCKVSIQVI 339 >UniRef50_Q4S489 Cluster: Chromosome 1 SCAF14742, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1 SCAF14742, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 891 Score = 206 bits (502), Expect = 9e-51 Identities = 158/538 (29%), Positives = 252/538 (46%), Gaps = 38/538 (7%) Query: 279 VQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA 338 V+A DAD G+N E+ Y+ T V + ID +G +Y GQ+DRE + + V A Sbjct: 333 VRANDADTGINGEIDYSFHQASDT--VQRLLRIDRFTGIIYVKGQVDREEENFLKFFVAA 390 Query: 339 TDGGDPPRSATATXXXXXXXXXXXXXXF-MPGQYEV-------ELAEDEPPGTPVVTLTA 390 D G +++ + G V ++ED P GTPV + Sbjct: 391 RDRGPNSKTSKVLVTITVKDQNDNSPSIEIRGIGLVTHRNGVANISEDMPVGTPVALVQV 450 Query: 391 TDADE-DNRLHYEITGGNT--RGRFSITSQNGRG---LITVAQPLDFKQERRYVLTVSAT 444 +D DE +N + + G+ + R + S N R + LD+++ + Y + + A Sbjct: 451 SDRDEGENAVVTCVVAGDVPFQLRPASESSNDRKRKYFLQTTTLLDYERVKDYRIEIVAV 510 Query: 445 DSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502 DSG S T +++ +TD N+ P+F E G VL V ATD+D G NA Sbjct: 511 DSGNPALSSTNFLKVQVTDVNDNIPIFSPPLLKVDFAEGNYPGDKVLDVLATDADSGSNA 570 Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 ++TYS+S + E F ++ +G + +L+RE Y V A D GVP + Sbjct: 571 ELTYSISEPAALEL-------FEVDANSGEVRVRAVLNREQREHYRFHVAAADKGVPGKT 623 Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP 622 T VEI+V+DVNDN+P F Y+ ++ E+ V V TD D G N R+ ++P Sbjct: 624 GTATVEITVLDVNDNDPKFMLDDYSFSVNENMAPLNPVGVVTVTDGDKGENARVTLLVEP 683 Query: 623 KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND 682 + G FVI +G I ++ + DRE +T+ + A+D G PP++S V V I + D ND Sbjct: 684 ---DNGKFVIQNGTGTILSSISFDREKESTYTFRLKAVDAGDPPRTSYVAVTINVLDEND 740 Query: 683 SPP-VFESDCLTF-YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR 740 + P V + TF ++ ++P T + + A D D G NA + Y++ GG+ F + Sbjct: 741 NAPYVTKPSNSTFTHLLPDTPPDTRVAVVEAEDIDSGLNAELVYTLAGGNPFGLFRIAPG 800 Query: 741 QGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMK 795 G +T+ S R + LV+R + PP V + V + N +++ Sbjct: 801 SGE-----ITLAQKLAGSHRGLHRLVVRVSDRGKPPRHTTALVHVFVNETKYNTSLIE 853 Score = 193 bits (470), Expect = 7e-47 Identities = 200/757 (26%), Positives = 319/757 (42%), Gaps = 55/757 (7%) Query: 138 VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQ 197 + ++D NDN PQFS T+S+ E+ V + A ATD D GAN Y + G Sbjct: 102 IEVLDINDNTPQFSSPILTLSIPENTQV--GALFAIPMATDRDAGANGVAEYTLTAGPDA 159 Query: 198 MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP-R 256 Q SL +D ++ + +LV+ G+ R +NIR V+ P R Sbjct: 160 DQL--------FSLQVAVDSDE-KVPQLVVM----GNLDREKKDSYDLNIRVVDGGRPAR 206 Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316 ++L + SV++ R Y+A+ N+ Y++ + P+ S Sbjct: 207 ASSALLRVSVTDQNDNQPKFERSH-YEAELTENSPQGYSVLQPRPPAS---PVCSGSASW 262 Query: 317 WVYTSGQLDRETQAKYQLLVTATDGGDPPR------SATATXXXXXXXXXXXXXXFMPGQ 370 +++ S ++ + Q+ + ++ G PPR A G Sbjct: 263 FLFLS-RVSPDAQSGF---ISQPGGTSPPRWLLVNQRANTGWKAVALGAQPTGSALQDGW 318 Query: 371 YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 V + V A DAD + + Y + + + G+I V Sbjct: 319 ISVSNRRRRLVASEV---RANDADTGINGEIDYSFHQASDTVQRLLRIDRFTGIIYVKGQ 375 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFE--------NAPYTASV 478 +D ++E V+A D G S T+ V + IT D N+ +P E + A++ Sbjct: 376 VDREEENFLKFFVAARDRGPNSKTSKVLVTITVKDQNDNSPSIEIRGIGLVTHRNGVANI 435 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 ED P+GT V +V +D D G NA +T ++ ++ + + + + + T L Sbjct: 436 SEDMPVGTPVALVQVSDRDEGENAVVTCVVAGDVPFQ-LRPASESSNDRKRKYFLQTTTL 494 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 LD E + Y + + A D G P+LS T +++ V DVNDN P+F L + E G Sbjct: 495 LDYERVKDYRIEIVAVDSGNPALSSTNFLKVQVTDVNDNIPIFSPPLLKVDFAEGNYPGD 554 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 V V ATDAD G N + Y + E F +D SG +R L+RE + Sbjct: 555 KVLDVLATDADSGSNAELTYSISEPAALE-LFEVDANSGEVRVRAVLNREQREHYRFHVA 613 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 A D G P ++ T V I + D+ND+ P F D +F ++EN +G + D D+G Sbjct: 614 AADKGVPGKTGTATVEITVLDVNDNDPKFMLDDYSFSVNENMAPLNPVGVVTVTDGDKGE 673 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDV 778 NA V ++ D+ F ++ G+ + + D + ES + A PP + V Sbjct: 674 NARVTLLVE--PDNGKFVIQNGTGTILSSI--SFDREKESTYTFRLKAVDAGDPPRTSYV 729 Query: 779 RVEILVTDVNDNAP-VMKDFQIIFNNY-KDCFPVGPFGRVPAYDAD--VTDKLQYRILSG 834 V I V D NDNAP V K F + D P V A D D + +L Y + G Sbjct: 730 AVTINVLDENDNAPYVTKPSNSTFTHLLPDTPPDTRVAVVEAEDIDSGLNAELVYTLAGG 789 Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 N L + +G +TL+ +L + L + V V+D Sbjct: 790 NPFGLFRIAPGSGEITLAQKLAGSHRGLHRLVVRVSD 826 Score = 193 bits (470), Expect = 7e-47 Identities = 158/538 (29%), Positives = 246/538 (45%), Gaps = 30/538 (5%) Query: 170 VIAKIKATDADVGANSAIRYAIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVI 227 V ++++A DAD G N I Y+ + +Q ID +G + + +D E+ + + Sbjct: 329 VASEVRANDADTGINGEIDYSFHQASDTVQRLLRIDRFTGIIYVKGQVDREEENFLKFFV 388 Query: 228 RAQDGGSPSRSNTTQLLINIRDVNDNAPRFY---TSLFQE-----SVSENVPIGYSIVRV 279 A+D G S+++ + I ++D NDN+P L ++SE++P+G + V Sbjct: 389 AARDRGPNSKTSKVLVTITVKDQNDNSPSIEIRGIGLVTHRNGVANISEDMPVGTPVALV 448 Query: 280 QAYDADEGVNAELTYTMT-DKDYTGNVDLPITID-PRSGWVYTSGQLDRETQAKYQLLVT 337 Q D DEG NA +T + D + + D R ++ T+ LD E Y++ + Sbjct: 449 QVSDRDEGENAVVTCVVAGDVPFQLRPASESSNDRKRKYFLQTTTLLDYERVKDYRIEIV 508 Query: 338 ATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN 397 A D G+P S+T F P +V+ AE PG V+ + ATDAD + Sbjct: 509 AVDSGNPALSSTNFLKVQVTDVNDNIPIFSPPLLKVDFAEGNYPGDKVLDVLATDADSGS 568 Query: 398 --RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTA 453 L Y I+ F + + +G + V L+ +Q Y V+A D G G++ TA Sbjct: 569 NAELTYSISEPAALELFEVDANSGE--VRVRAVLNREQREHYRFHVAAADKGVPGKTGTA 626 Query: 454 MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513 V+I + D N+ P F Y+ SV E+ V VV+ TD D G NA++T + + Sbjct: 627 TVEITVLDVNDNDPKFMLDDYSFSVNENMAPLNPVGVVTVTDGDKGENARVTLLVEPD-- 684 Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 + +FVI TG I ++ DRE S Y + A D G P + V I+V+D Sbjct: 685 -------NGKFVIQNGTGTILSSISFDREKESTYTFRLKAVDAGDPPRTSYVAVTINVLD 737 Query: 574 VNDNEP-VFKQQLYT-ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631 NDN P V K T +++ D T V+ V A D D GLN + Y L G F Sbjct: 738 ENDNAPYVTKPSNSTFTHLLPDTPPDTRVAVVEAEDIDSGLNAELVYTL-AGGNPFGLFR 796 Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES 689 I P SG I + L H L D G PP+ +T +VH+ + + + + E+ Sbjct: 797 IAPGSGEITLAQKLAGSHRGLHRLVVRVSDRGKPPRHTTALVHVFVNETKYNTSLIEA 854 Score = 186 bits (453), Expect = 8e-45 Identities = 167/567 (29%), Positives = 251/567 (44%), Gaps = 61/567 (10%) Query: 45 LKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS 104 ++A D D G N E++Y+ + DT VQ + RID +G + + Sbjct: 333 VRANDADTGINGEIDYSFHQAS-DT----------------VQRLLRIDRFTGIIYVKGQ 375 Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQF--------SEKTYT 156 +DRE+ V A D+ P S +S + + + D NDN P + + Sbjct: 376 VDREEENFLKFFVAARDR-GPNSK--TSKVLVTITVKDQNDNSPSIEIRGIGLVTHRNGV 432 Query: 157 VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD-------V 209 ++ ED+ V PV A ++ +D D G N+ + ++ G+ Q S S + + Sbjct: 433 ANISEDMPV-GTPV-ALVQVSDRDEGENAVVT-CVVAGDVPFQLRPASESSNDRKRKYFL 489 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269 LDYE+V+ YR+ I A D G+P+ S+T L + + DVNDN P F L + +E Sbjct: 490 QTTTLLDYERVKDYRIEIVAVDSGNPALSSTNFLKVQVTDVNDNIPIFSPPLLKVDFAEG 549 Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329 G ++ V A DAD G NAELTY++++ ++L +D SG V L+RE + Sbjct: 550 NYPGDKVLDVLATDADSGSNAELTYSISE---PAALEL-FEVDANSGEVRVRAVLNREQR 605 Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLT 389 Y+ V A D G P ++ TAT FM Y + E+ P PV +T Sbjct: 606 EHYRFHVAAADKGVPGKTGTATVEITVLDVNDNDPKFMLDDYSFSVNENMAPLNPVGVVT 665 Query: 390 ATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG- 448 TD D+ + G+F I QNG G I + D ++E Y + A D+G Sbjct: 666 VTDGDKGENARVTLLVEPDNGKFVI--QNGTGTILSSISFDREKESTYTFRLKAVDAGDP 723 Query: 449 -RSDTAMVQINITDANNYAPVF---ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504 R+ V IN+ D N+ AP N+ +T + D P T V VV A D D G+NA++ Sbjct: 724 PRTSYVAVTINVLDENDNAPYVTKPSNSTFT-HLLPDTPPDTRVAVVEAEDIDSGLNAEL 782 Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT 564 Y+L A + F I P +G IT + L + L V D G P T Sbjct: 783 VYTL-------AGGNPFGLFRIAPGSGEITLAQKLAGSHRGLHRLVVRVSDRGKPPRHTT 835 Query: 565 TDVEISVVDVNDN----EPVFKQQLYT 587 V + V + N E + LYT Sbjct: 836 ALVHVFVNETKYNTSLIEALVGHSLYT 862 Score = 144 bits (348), Expect = 4e-32 Identities = 108/344 (31%), Positives = 166/344 (48%), Gaps = 34/344 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ V D ND+ P+F + EG G VL + ATD D G NAE+ Y+I Sbjct: 524 KVQVTDVNDNIPIFSPPLLKVDFAEGNYPGDKVLDVLATDADSGSNAELTYSIS------ 577 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 E A ++F +D SG + RA L+RE+ Y V A D+ P Sbjct: 578 ---EPAAL----------ELFEVDANSGEVRVRAVLNREQREHYRFHVAAADKGVPGK-- 622 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + TAT+ + ++D NDN P+F Y+ SV+E+++ NPV + TD D G N+ + Sbjct: 623 -TGTATVEITVLDVNDNDPKFMLDDYSFSVNENMAPL-NPV-GVVTVTDGDKGENARVTL 679 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 + N +F I + +G + + D E+ +Y ++A D G P R++ + IN+ D Sbjct: 680 LVEPDNG--KFVIQNGTGTILSSISFDREKESTYTFRLKAVDAGDPPRTSYVAVTINVLD 737 Query: 250 VNDNAP---RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 NDNAP + S F + + P + V+A D D G+NAEL YT+ GN Sbjct: 738 ENDNAPYVTKPSNSTFTHLLPDTPP-DTRVAVVEAEDIDSGLNAELVYTLAG----GNPF 792 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350 I P SG + + +L + ++L+V +D G PPR TA Sbjct: 793 GLFRIAPGSGEITLAQKLAGSHRGLHRLVVRVSDRGKPPRHTTA 836 Score = 79.0 bits (186), Expect = 2e-12 Identities = 53/179 (29%), Positives = 84/179 (46%), Gaps = 10/179 (5%) Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 N L + + +++T G+ S + I V+D+NDN P F + T +I E+ Sbjct: 69 NPLAGDKCFLEFEVSITDMVKGLGSGPRLIEGRIEVLDINDNTPQFSSPILTLSIPENTQ 128 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG--------VIRTNKALDR 647 VG + ATD D G NG Y L + F + A V+ N LDR Sbjct: 129 VGALFAIPMATDRDAGANGVAEYTLTAGPDADQLFSLQVAVDSDEKVPQLVVMGN--LDR 186 Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706 E ++DL +DGG P ++S+ ++ + + D ND+ P FE ++ENSP G ++ Sbjct: 187 EKKDSYDLNIRVVDGGRPARASSALLRVSVTDQNDNQPKFERSHYEAELTENSPQGYSV 245 Score = 73.7 bits (173), Expect = 7e-11 Identities = 42/147 (28%), Positives = 70/147 (47%) Query: 456 QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515 +I + D N+ P F + T S+ E+ +G + ATD D G N Y+L++ + Sbjct: 101 RIEVLDINDNTPQFSSPILTLSIPENTQVGALFAIPMATDRDAGANGVAEYTLTAGPDAD 160 Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575 + + + + LDRE Y L + DGG P+ + + + +SV D N Sbjct: 161 QLFSLQVAVDSDEKVPQLVVMGNLDREKKDSYDLNIRVVDGGRPARASSALLRVSVTDQN 220 Query: 576 DNEPVFKQQLYTANIMEDALVGTSVSQ 602 DN+P F++ Y A + E++ G SV Q Sbjct: 221 DNQPKFERSHYEAELTENSPQGYSVLQ 247 Score = 66.5 bits (155), Expect = 1e-08 Identities = 47/161 (29%), Positives = 69/161 (42%), Gaps = 15/161 (9%) Query: 2 SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 S P I +I VLD ND++P F S+ E G ATD+D G N EYT Sbjct: 93 SGPRLIEGRIEVLDINDNTPQFSSPILTLSIPENTQVGALFAIPMATDRDAGANGVAEYT 152 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121 + T P+ +Q D + L+ +LDREK Y + ++ D Sbjct: 153 L------TAGPD------ADQLFSLQVAVDSDEKVPQLVVMGNLDREKKDSYDLNIRVVD 200 Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162 P +S+A + V++ D NDN P+F Y + E+ Sbjct: 201 GGRPAR---ASSALLRVSVTDQNDNQPKFERSHYEAELTEN 238 >UniRef50_Q9Y5H0 Cluster: Protocadherin gamma A3 precursor; n=173; Mammalia|Rep: Protocadherin gamma A3 precursor - Homo sapiens (Human) Length = 932 Score = 204 bits (499), Expect = 2e-50 Identities = 166/611 (27%), Positives = 275/611 (45%), Gaps = 32/611 (5%) Query: 194 GNTQMQFSIDSLSGDVSLVKTLDYEQV-RSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252 G TQ+ FS++ SG + + +D E++ L + + + ++ I I+D+ND Sbjct: 70 GRTQL-FSLNPQSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDIND 128 Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312 NAP F T + + E G A+D D G+N+ Y ++ DY ++ Sbjct: 129 NAPNFPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEG 188 Query: 313 PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYE 372 + + LDRE + +QL++ A+DGGDP S F +Y Sbjct: 189 AKYPELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYR 248 Query: 373 VELAEDEPPGTPVVTLTATDADE--DNRLHYEITG--GNTRGRFSITSQNGRGLITVAQP 428 V + E+ P GT ++T+ ATD DE + ++ Y + G F + S +G +++ + Sbjct: 249 VSVWENVPVGTRLLTVNATDPDEGFNAQVSYILDKMPGKIAEIFHLNSVSGE--VSILKS 306 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 LD++ Y + + A D G A + + + D N+ AP T+SV E+ +G + Sbjct: 307 LDYEDAMFYEIKIEAQDGPGLLSRAKILVTVLDVNDNAPEITITSLTSSVPEEGTVGREI 366 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 ++ D D G N Q+ + + + DQ + + T LDRE +S Y Sbjct: 367 ALIDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYY-------RLVTATSLDREQISEYN 419 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 +++ A DGG P LS T + + V+D+NDN P F Y+A I E+ G S+ V A D Sbjct: 420 ISLRASDGGSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDP 479 Query: 609 DVGLNGRIHYELDPKDREEG----SFV-IDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 D N RI Y L +D +G SFV I+ +GV+ ++ D E L A D G Sbjct: 480 DSNNNARITYALT-EDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSG 538 Query: 664 TPPQSSTVIVHIKIEDINDSPP-----VFESDCLTFY--ISENSPIGTTIGEIRAHDPDE 716 PP SS V +++ + D ND+ P +D T ++ G + ++ A D D Sbjct: 539 NPPLSSNVSLNLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDS 598 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR-AASPPLW 775 G NA + Y + + FS+ G + LD ++ ++ + I+ PPL Sbjct: 599 GQNAWLSYRLLKASEPGLFSVGLHTGEVRTARAL---LDRDALKQSLVVAIQDHGQPPLS 655 Query: 776 NDVRVEILVTD 786 V + + V D Sbjct: 656 ATVTLIVAVAD 666 Score = 201 bits (490), Expect = 3e-49 Identities = 176/608 (28%), Positives = 275/608 (45%), Gaps = 32/608 (5%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +F ++ +SG+L+T +DRE++ L V D+L + + I D NDN P Sbjct: 74 LFSLNPQSGSLVTAERIDREELCAQIPLCLVKINIL-VEDKLK-IFEVEIEIKDINDNAP 131 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG- 207 F + + + E ++V K A D DVG NS Y + N +++S+S Sbjct: 132 NFPTEELEIKIGE-LTVPGTRFPIKT-AFDPDVGINSLQNYKL-SPNDYFSLAVNSVSEG 188 Query: 208 ----DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263 ++ L + LD E+ ++LV+ A DGG P S + + + D NDN P F ++ Sbjct: 189 AKYPELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYR 248 Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323 SV ENVP+G ++ V A D DEG NA+++Y + DK G + ++ SG V Sbjct: 249 VSVWENVPVGTRLLTVNATDPDEGFNAQVSYIL-DK-MPGKIAEIFHLNSVSGEVSILKS 306 Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383 LD E Y++ + A DG P + A + E+ G Sbjct: 307 LDYEDAMFYEIKIEAQDG--PGLLSRAKILVTVLDVNDNAPEITITSLTSSVPEEGTVGR 364 Query: 384 PVVTLTATDADEDNRLHYEI-TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 + + D D E+ GN + + L+T A LD +Q Y +++ Sbjct: 365 EIALIDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVT-ATSLDREQISEYNISLR 423 Query: 443 ATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 A+D G S + +++ D N+ P F + Y+A + E+ P G ++ V+A D D Sbjct: 424 ASDGGSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNN 483 Query: 501 NAQITYSLSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 NA+ITY+L+ + A FV IN TG + + D E L VTA D G P Sbjct: 484 NARITYALTEDTLQGAPL---SSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNP 540 Query: 560 SLSDTTDVEISVVDVNDNEP-VFKQQLYTAN------IMEDALVGTSVSQVGATDADVGL 612 LS + + V+D NDN P + L T A G V++V A D D G Sbjct: 541 PLSSNVSLNLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQ 600 Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKA-LDRESVATHDLKAVAIDGGTPPQSSTV 671 N + Y L K E G F + +G +RT +A LDR+++ + A+ D G PP S+TV Sbjct: 601 NAWLSYRL-LKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAIQ-DHGQPPLSATV 658 Query: 672 IVHIKIED 679 + + + D Sbjct: 659 TLIVAVAD 666 Score = 188 bits (459), Expect = 1e-45 Identities = 141/493 (28%), Positives = 231/493 (46%), Gaps = 18/493 (3%) Query: 310 TIDPRSGWVYTSGQLDRETQ-AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 +++P+SG + T+ ++DRE A+ L + + + F Sbjct: 76 SLNPQSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDINDNAPNFPT 135 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQNGRGL---IT 424 + E+++ E PGT TA D D N L N ++ S + + Sbjct: 136 EELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPNDYFSLAVNSVSEGAKYPELV 195 Query: 425 VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 + + LD +++ + L + A+D G S +Q+ + DAN+ P+F Y SV+E+ Sbjct: 196 LERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRVSVWENV 255 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 P+GT +L V+ATD D G NAQ++Y L A H +N +G ++ K LD E Sbjct: 256 PVGTRLLTVNATDPDEGFNAQVSYILDKMPGKIAEIFH-----LNSVSGEVSILKSLDYE 310 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 Y + + A+DG P L + ++V+DVNDN P T+++ E+ VG ++ Sbjct: 311 DAMFYEIKIEAQDG--PGLLSRAKILVTVLDVNDNAPEITITSLTSSVPEEGTVGREIAL 368 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 + D D G NG++ + + ID ++ T +LDRE ++ +++ A DG Sbjct: 369 IDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLV-TATSLDREQISEYNISLRASDG 427 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 G+PP S+ + + + DIND+PP F + YI EN+P G +I + A DPD NA + Sbjct: 428 GSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNNNARI 487 Query: 723 HYSIKGGD-DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--PPLWNDVR 779 Y++ S S+ L + DYE R LV + S PPL ++V Sbjct: 488 TYALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNVS 547 Query: 780 VEILVTDVNDNAP 792 + + V D NDNAP Sbjct: 548 LNLFVLDQNDNAP 560 Score = 177 bits (432), Expect = 3e-42 Identities = 140/468 (29%), Positives = 213/468 (45%), Gaps = 38/468 (8%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 +H Q+ VLD ND+ P+F +Y SV E GT +LT+ ATD D G NA+V Y ++ + Sbjct: 226 LHIQVIVLDANDNPPMFTQPEYRVSVWENVPVGTRLLTVNATDPDEGFNAQVSYILDKMP 285 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 + ++F ++ SG + SLD E Y + ++A D Sbjct: 286 GK-----------------IAEIFHLNSVSGEVSILKSLDYEDAMFYEIKIEAQDGPG-- 326 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 L S A I V ++D NDN P+ + + T SV E+ +V IA I D D G N Sbjct: 327 ---LLSRAKILVTVLDVNDNAPEITITSLTSSVPEEGTVGRE--IALIDVHDRDSGQNGQ 381 Query: 187 IRYAIIGGNT-QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 + ++G +++ SID V+ +LD EQ+ Y + +RA DGGSP S T + + Sbjct: 382 VEVFVLGNLPFKLEKSIDQYYRLVTAT-SLDREQISEYNISLRASDGGSPPLSTETHITL 440 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-N 304 ++ D+NDN P F + + EN P G SI V A D D NA +TY +T+ G Sbjct: 441 HVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDSNNNARITYALTEDTLQGAP 500 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 + ++I+ +G +Y D E +LLVTA+D G+PP S+ + Sbjct: 501 LSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPPLSSNVSLNLFVLDQNDNAP 560 Query: 365 XFM------PGQYEVELA-EDEPPGTPVVTLTATDADEDNR--LHYEITGGNTRGRFSIT 415 + G VELA PG V + A D D L Y + + G FS+ Sbjct: 561 EILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFSVG 620 Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDAN 463 G + A+ L + + L V+ D G +A V + + A+ Sbjct: 621 LHTGE--VRTARALLDRDALKQSLVVAIQDHGQPPLSATVTLIVAVAD 666 Score = 133 bits (321), Expect = 8e-29 Identities = 96/280 (34%), Positives = 138/280 (49%), Gaps = 16/280 (5%) Query: 522 QQFVINPQTGAITTNKLLDRETMSGYL-LTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580 Q F +NPQ+G++ T + +DRE + + L + + V +VEI + D+NDN P Sbjct: 73 QLFSLNPQSGSLVTAERIDREELCAQIPLCLVKINILVEDKLKIFEVEIEIKDINDNAPN 132 Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS-GV- 638 F + I E + GT A D DVG+N +Y+L P D S ++ S G Sbjct: 133 FPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKLSPND--YFSLAVNSVSEGAK 190 Query: 639 ---IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695 + +ALDRE H L VA DGG P S + + + + D ND+PP+F Sbjct: 191 YPELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPPMFTQPEYRVS 250 Query: 696 ISENSPIGTTIGEIRAHDPDEGPNAVVHYSI--KGGDDSNSFSLETRQGSDKAELVTMVD 753 + EN P+GT + + A DPDEG NA V Y + G + F L + G E+ + Sbjct: 251 VWENVPVGTRLLTVNATDPDEGFNAQVSYILDKMPGKIAEIFHLNSVSG----EVSILKS 306 Query: 754 LDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAP 792 LDYE YE+ I A P L + ++ + V DVNDNAP Sbjct: 307 LDYED-AMFYEIKIEAQDGPGLLSRAKILVTVLDVNDNAP 345 Score = 72.9 bits (171), Expect = 1e-10 Identities = 75/284 (26%), Positives = 129/284 (45%), Gaps = 14/284 (4%) Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGS---FVIDPASGVIRTNKALDRESVATH-DLK 656 S VG D+GL R E + G F ++P SG + T + +DRE + L Sbjct: 43 SFVGNIANDLGLEPRELAERGVRIVSRGRTQLFSLNPQSGSLVTAERIDREELCAQIPLC 102 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 V I+ + V I+I+DIND+ P F ++ L I E + GT A DPD Sbjct: 103 LVKINILVEDKLKIFEVEIEIKDINDNAPNFPTEELEIKIGELTVPGTRFPIKTAFDPDV 162 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PP 773 G N++ +Y + D + +G+ ELV LD E ++ ++LV+ A+ P Sbjct: 163 GINSLQNYKLSPNDYFSLAVNSVSEGAKYPELVLERALDREK-KEIHQLVLVASDGGDPV 221 Query: 774 LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDAD--VTDKLQYR 830 ++ ++++V D NDN P+ + + +++ PVG V A D D ++ Y Sbjct: 222 HSGNLHIQVIVLDANDNPPMFTQPEYRVSVWEN-VPVGTRLLTVNATDPDEGFNAQVSYI 280 Query: 831 I--LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 + + G A + LN +G +++ L+ +++ DG Sbjct: 281 LDKMPGKIAEIFHLNSVSGEVSILKSLDYEDAMFYEIKIEAQDG 324 >UniRef50_UPI00006A0F40 Cluster: Protocadherin gamma C3 precursor (PCDH-gamma-C3) (Protocadherin 43) (PC-43) (Protocadherin 2).; n=2; Xenopus tropicalis|Rep: Protocadherin gamma C3 precursor (PCDH-gamma-C3) (Protocadherin 43) (PC-43) (Protocadherin 2). - Xenopus tropicalis Length = 932 Score = 204 bits (498), Expect = 3e-50 Identities = 167/584 (28%), Positives = 270/584 (46%), Gaps = 55/584 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ +LD ND+SP F+ + + E AS G L A D DIG NA EY Sbjct: 122 EVEILDINDNSPRFQGDELTLKINELASPGARFLIPNAQDPDIGSNALQEY--------H 173 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 L+P + R DG + L+ +LDRE+ A + +++KA D P Sbjct: 174 LSPSENFALIVKK--------RTDGSKFPELILEKALDREQTAVHHLVLKAEDGGVP--- 222 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 SST I+V ++D NDN+P F + +Y V + E + N ++ K+ ATD D G N I Sbjct: 223 SRSSTMQINVIVLDANDNHPAFDQPSYNVQLKE--NAPKNSLVIKLNATDLDEGPNGEIE 280 Query: 189 YAIIGGNTQMQ---FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 Y N+ F ++S +G++ ++ LD+E+V Y + I A+D G+P +++ Sbjct: 281 YFFSSHNSDALSNIFQLNSETGEIRVLGNLDFEEVSVYEIDIEARDKGTPIMEEHCSVIV 340 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 +I DVNDN P S F SV E+ P G + + D D G N + DK N+ Sbjct: 341 HIIDVNDNTPEMTISAFSSSVPEDSPAGTVVAVITIKDKDHGDNGRV-QCQVDK----NI 395 Query: 306 DLPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 + D + + TS LDRE+ ++Y + +TA D G+PP S Sbjct: 396 PFTVREDFEHQFSLITSDNLDRESVSEYHITITAKDMGNPPLSTEKVISVVVSDVNDNAP 455 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTAT--DADEDNRLHYEITGG-----NTRGRFSITSQ 417 F+ YEV + E+ G + T++A+ D D+++RL Y I + I S+ Sbjct: 456 QFVEPVYEVFVEENNKAGELLCTVSASDPDLDQNSRLSYTIIQNPKEDYASSSHIYINSE 515 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYT 475 NG+ + + PLD+++ + + D+G + +V + + D N+ APV Sbjct: 516 NGQ--VYLKFPLDYERINYFRFQIEVADAGSPPLKNKTVVHVFVLDQNDNAPVVVFPIVG 573 Query: 476 ASVFEDAPI----GTTVLV--VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 A+ I G V+V +SA D D G NA ++Y+L A F + + Sbjct: 574 ANSVAHCKIPLLTGPNVMVSKISAVDYDSGRNAWLSYNLLD-------ATDPTLFSVVLR 626 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 TG I T + + + + L + +D G P LS + V +++ D Sbjct: 627 TGEIKTKRAIQDIDPTIHELLLLVKDSGDPCLSTSVTVMMTLED 670 Score = 204 bits (497), Expect = 4e-50 Identities = 164/607 (27%), Positives = 271/607 (44%), Gaps = 30/607 (4%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F I+ +GA+L +DRE + +V + + + I V I+D NDN P+ Sbjct: 77 FSINVNNGAILVNDRIDRELLCAQSVTCILNLKFA--IENPVEVYRIEVEILDINDNSPR 134 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG-- 207 F T+ ++E S +I A D D+G+N+ Y + G Sbjct: 135 FQGDELTLKINELASPGARFLIPN--AQDPDIGSNALQEYHLSPSENFALIVKKRTDGSK 192 Query: 208 --DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265 ++ L K LD EQ + LV++A+DGG PSRS+T Q+ + + D NDN P F + Sbjct: 193 FPELILEKALDREQTAVHHLVLKAEDGGVPSRSSTMQINVIVLDANDNHPAFDQPSYNVQ 252 Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMT--DKDYTGNVDLPITIDPRSGWVYTSGQ 323 + EN P ++++ A D DEG N E+ Y + + D N+ ++ +G + G Sbjct: 253 LKENAPKNSLVIKLNATDLDEGPNGEIEYFFSSHNSDALSNI---FQLNSETGEIRVLGN 309 Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383 LD E + Y++ + A D G P + + + ED P GT Sbjct: 310 LDFEEVSVYEIDIEARDKGTPIMEEHCSVIVHIIDVNDNTPEMTISAFSSSVPEDSPAGT 369 Query: 384 PVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441 V +T D D ++ R+ ++ N ++ LIT + LD + Y +T+ Sbjct: 370 VVAVITIKDKDHGDNGRVQCQV-DKNIPFTVREDFEHQFSLIT-SDNLDRESVSEYHITI 427 Query: 442 SATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499 +A D G S ++ + ++D N+ AP F Y V E+ G + VSA+D D+ Sbjct: 428 TAKDMGNPPLSTEKVISVVVSDVNDNAPQFVEPVYEVFVEENNKAGELLCTVSASDPDLD 487 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 N++++Y++ + + IN + G + LD E ++ + + D G P Sbjct: 488 QNSRLSYTIIQNPKEDYAS--SSHIYINSENGQVYLKFPLDYERINYFRFQIEVADAGSP 545 Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA----LVGTS--VSQVGATDADVGLN 613 L + T V + V+D NDN PV + AN + L G + VS++ A D D G N Sbjct: 546 PLKNKTVVHVFVLDQNDNAPVVVFPIVGANSVAHCKIPLLTGPNVMVSKISAVDYDSGRN 605 Query: 614 GRIHYE-LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672 + Y LD D S V+ +G I+T +A+ H+L + D G P S++V Sbjct: 606 AWLSYNLLDATDPTLFSVVL--RTGEIKTKRAIQDIDPTIHELLLLVKDSGDPCLSTSVT 663 Query: 673 VHIKIED 679 V + +ED Sbjct: 664 VMMTLED 670 Score = 188 bits (457), Expect = 3e-45 Identities = 135/463 (29%), Positives = 227/463 (49%), Gaps = 20/463 (4%) Query: 423 ITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 + + + LD +Q + L + A D G RS T + + + DAN+ P F+ Y + E Sbjct: 196 LILEKALDREQTAVHHLVLKAEDGGVPSRSSTMQINVIVLDANDNHPAFDQPSYNVQLKE 255 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 +AP + V+ ++ATD D G N +I Y SS +++A+++ F +N +TG I LD Sbjct: 256 NAPKNSLVIKLNATDLDEGPNGEIEYFFSSH-NSDALSNI---FQLNSETGEIRVLGNLD 311 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 E +S Y + + ARD G P + + V + ++DVNDN P +++++ ED+ GT V Sbjct: 312 FEEVSVYEIDIEARDKGTPIMEEHCSVIVHIIDVNDNTPEMTISAFSSSVPEDSPAGTVV 371 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 + + D D G NGR+ ++D + +I T+ LDRESV+ + + A Sbjct: 372 AVITIKDKDHGDNGRVQCQVDKNIPFTVREDFEHQFSLI-TSDNLDRESVSEYHITITAK 430 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 D G PP S+ ++ + + D+ND+ P F ++ EN+ G + + A DPD N+ Sbjct: 431 DMGNPPLSTEKVISVVVSDVNDNAPQFVEPVYEVFVEENNKAGELLCTVSASDPDLDQNS 490 Query: 721 VVHYS-IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYEL-VIRAASPPLWND 777 + Y+ I+ + + S S+ ++ LDYE ++++ V A SPPL N Sbjct: 491 RLSYTIIQNPKEDYASSSHIYINSENGQVYLKFPLDYERINYFRFQIEVADAGSPPLKNK 550 Query: 778 VRVEILVTDVNDNAPVMKDFQII-FNNYKDC-FPV--GP---FGRVPA--YDADVTDKLQ 828 V + V D NDNAPV+ F I+ N+ C P+ GP ++ A YD+ L Sbjct: 551 TVVHVFVLDQNDNAPVVV-FPIVGANSVAHCKIPLLTGPNVMVSKISAVDYDSGRNAWLS 609 Query: 829 YRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 Y +L + L + TG + + P + + + V D Sbjct: 610 YNLLDATDPTLFSVVLRTGEIKTKRAIQDIDPTIHELLLLVKD 652 Score = 128 bits (308), Expect = 3e-27 Identities = 86/282 (30%), Positives = 134/282 (47%), Gaps = 13/282 (4%) Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLT-VTARDGGVPSLSDTTDVEISVVDVNDNEPV 580 Q F IN GAI N +DRE + +T + + + + +E+ ++D+NDN P Sbjct: 75 QYFSINVNNGAILVNDRIDRELLCAQSVTCILNLKFAIENPVEVYRIEVEILDINDNSPR 134 Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640 F+ T I E A G A D D+G N Y L P E + ++ + + Sbjct: 135 FQGDELTLKINELASPGARFLIPNAQDPDIGSNALQEYHLSPS--ENFALIVKKRTDGSK 192 Query: 641 -----TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695 KALDRE A H L A DGG P +SST+ +++ + D ND+ P F+ Sbjct: 193 FPELILEKALDREQTAVHHLVLKAEDGGVPSRSSTMQINVIVLDANDNHPAFDQPSYNVQ 252 Query: 696 ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755 + EN+P + + ++ A D DEGPN + Y +S++ S + S+ E+ + +LD Sbjct: 253 LKENAPKNSLVIKLNATDLDEGPNGEIEYFF-SSHNSDALSNIFQLNSETGEIRVLGNLD 311 Query: 756 YESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVM 794 +E YE+ I A +P + V + + DVNDN P M Sbjct: 312 FEEV-SVYEIDIEARDKGTPIMEEHCSVIVHIIDVNDNTPEM 352 >UniRef50_O93509 Cluster: Paraxial protocadherin; n=11; Xenopus|Rep: Paraxial protocadherin - Xenopus laevis (African clawed frog) Length = 979 Score = 204 bits (497), Expect = 4e-50 Identities = 173/606 (28%), Positives = 280/606 (46%), Gaps = 39/606 (6%) Query: 207 GDVSLVKTLDYEQVRSYRLVIR-AQDGGSPSRSNTTQL--LINIRDVNDNAPRFYTSLFQ 263 G +S+++ +D EQ+ L A D S S+ + L + +RD+ND++P F + + Sbjct: 76 GQLSIMERIDREQICRQSLHCNLALDVVSFSKGHFKLLNVKVEVRDINDHSPHFPSEIMH 135 Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP-RSGWVYTSG 322 VSE+ +G I A D D G N+ + +++ + ++D+ D + + Sbjct: 136 VEVSESSSVGTRIPLEIAIDEDVGSNSIQNFQISNNSHF-SIDVLTRADGVKYADLVLMR 194 Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382 +LDRE Q Y + + A DGG P S TA F V+L ED P G Sbjct: 195 ELDREIQPTYIMELLAMDGGVPSLSGTAVVNIRVLDFNDNSPVFERSTIAVDLVEDAPLG 254 Query: 383 TPVVTLTATDADE--DNRLHY---EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437 ++ L ATD DE + + Y + R F I S+ G +T+ +DF+ ++ Y Sbjct: 255 YLLLELHATDDDEGVNGEIVYGFSTLASQEVRQLFKINSRTGS--VTLEGQVDFETKQTY 312 Query: 438 VLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYT------ASVFEDAPIGTTVL 489 V A D G + T V ++I D N+ P P T A + E A + Sbjct: 313 EFEVQAQDLGPNPLTATCKVTVHILDVNDNTPAITITPLTTVNAGVAYIPETATKENFIA 372 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 ++S TD G N Q+ +L + ++ ++ I T LDRE ++ Y L Sbjct: 373 LISTTDRASGSNGQVRCTLYGHEHFKLQQAYEDSYM-------IVTTSTLDRENIAAYSL 425 Query: 550 TVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 TV A D G PSL + V D NDN PVF + Y A+I+E+ G+ ++ V A D+D Sbjct: 426 TVVAEDLGFPSLKTKKYYTVKVSDENDNAPVFSKPQYEASILENNAPGSYITTVIARDSD 485 Query: 610 VGLNGRIHYEL-DPKDREEG--SFV-IDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 NG+++Y L D K + +FV +D SGV+R ++LD E + D + A D G P Sbjct: 486 SDQNGKVNYRLVDAKVMGQSLTTFVSLDADSGVLRAVRSLDYEKLKQLDFEIEAADNGIP 545 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISE-----NSPIGTTIGEIRAHDPDEGPNA 720 S+ V ++++I D ND+ PV + L E ++P + +++A D DEG N+ Sbjct: 546 QLSTRVQLNLRIVDQNDNCPVITNPLLNNGSGEVLLPISAPQNYLVFQLKAEDSDEGHNS 605 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRV 780 + Y+I D S F++ G + L ++ D+ V P L + V Sbjct: 606 QLFYTIL-RDPSRLFAINKESG--EVFLKKQLNSDHSEDLSIVVAVYDLGRPSLSTNATV 662 Query: 781 EILVTD 786 + ++TD Sbjct: 663 KFILTD 668 Score = 178 bits (433), Expect = 2e-42 Identities = 167/608 (27%), Positives = 255/608 (41%), Gaps = 40/608 (6%) Query: 97 GALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT 156 G L +DRE++ R ++ S + V + D ND+ P F + Sbjct: 76 GQLSIMERIDREQICRQSLHCNLALDVVSFSKGHFKLLNVKVEVRDINDHSPHFPSEIMH 135 Query: 157 VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS-------GDV 209 V V E SV I A D DVG+NS + I + FSID L+ D+ Sbjct: 136 VEVSESSSVGTR--IPLEIAIDEDVGSNSIQNFQI---SNNSHFSIDVLTRADGVKYADL 190 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269 L++ LD E +Y + + A DGG PS S T + I + D NDN+P F S + E+ Sbjct: 191 VLMRELDREIQPTYIMELLAMDGGVPSLSGTAVVNIRVLDFNDNSPVFERSTIAVDLVED 250 Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329 P+GY ++ + A D DEGVN E+ Y + + V I+ R+G V GQ+D ET+ Sbjct: 251 APLGYLLLELHATDDDEGVNGEIVYGFSTL-ASQEVRQLFKINSRTGSVTLEGQVDFETK 309 Query: 330 AKYQLLVTATDGGDPPRSAT--ATXXXXXXXXXXXXXXFMP----GQYEVELAEDEPPGT 383 Y+ V A D G P +AT T P + E Sbjct: 310 QTYEFEVQAQDLGPNPLTATCKVTVHILDVNDNTPAITITPLTTVNAGVAYIPETATKEN 369 Query: 384 PVVTLTATDADEDNRLHYEIT-GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 + ++ TD + T G+ + ++ ++T + LD + Y LTV Sbjct: 370 FIALISTTDRASGSNGQVRCTLYGHEHFKLQQAYEDSYMIVTTS-TLDRENIAAYSLTVV 428 Query: 443 ATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 A D G S + ++D N+ APVF Y AS+ E+ G+ + V A DSD Sbjct: 429 AEDLGFPSLKTKKYYTVKVSDENDNAPVFSKPQYEASILENNAPGSYITTVIARDSDSDQ 488 Query: 501 NAQITYSLSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 N ++ Y L + + + FV ++ +G + + LD E + + A D G+P Sbjct: 489 NGKVNYRL---VDAKVMGQSLTTFVSLDADSGVLRAVRSLDYEKLKQLDFEIEAADNGIP 545 Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS------VSQVGATDADVGLN 613 LS + + +VD NDN PV L N + L+ S V Q+ A D+D G N Sbjct: 546 QLSTRVQLNLRIVDQNDNCPVITNPLLN-NGSGEVLLPISAPQNYLVFQLKAEDSDEGHN 604 Query: 614 GRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671 ++ Y + DP F I+ SG + K L+ + + D G P S+ Sbjct: 605 SQLFYTILRDP----SRLFAINKESGEVFLKKQLNSDHSEDLSIVVAVYDLGRPSLSTNA 660 Query: 672 IVHIKIED 679 V + D Sbjct: 661 TVKFILTD 668 Score = 172 bits (419), Expect = 1e-40 Identities = 156/590 (26%), Positives = 252/590 (42%), Gaps = 57/590 (9%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 ++ ++ V D NDHSP F + V E +S GT + A D+D+G N+ + I Sbjct: 113 LNVKVEVRDINDHSPHFPSEIMHVEVSESSSVGTRIPLEIAIDEDVGSNSIQNFQI---- 168 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASP 125 + + R DG + L+ LDRE Y + + A D P Sbjct: 169 ------------SNNSHFSIDVLTRADGVKYADLVLMRELDREIQPTYIMELLAMDGGVP 216 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 LS TA +++ ++D NDN P F T V + ED + ++ ++ ATD D G N Sbjct: 217 ---SLSGTAVVNIRVLDFNDNSPVFERSTIAVDLVEDAPL--GYLLLELHATDDDEGVNG 271 Query: 186 AIRY---AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 I Y + + F I+S +G V+L +D+E ++Y ++AQD G + T + Sbjct: 272 EIVYGFSTLASQEVRQLFKINSRTGSVTLEGQVDFETKQTYEFEVQAQDLGPNPLTATCK 331 Query: 243 LLINIRDVNDNAPRF-YTSLFQES-----VSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 + ++I DVNDN P T L + + E I + D G N ++ T+ Sbjct: 332 VTVHILDVNDNTPAITITPLTTVNAGVAYIPETATKENFIALISTTDRASGSNGQVRCTL 391 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 ++ L + S + T+ LDRE A Y L V A D G P Sbjct: 392 YGHEH---FKLQQAYED-SYMIVTTSTLDRENIAAYSLTVVAEDLGFPSLKTKKYYTVKV 447 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSI 414 F QYE + E+ PG+ + T+ A D+D D +++Y + G+ S+ Sbjct: 448 SDENDNAPVFSKPQYEASILENNAPGSYITTVIARDSDSDQNGKVNYRLVDAKVMGQ-SL 506 Query: 415 TS----QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN--ITDANNYAPV 468 T+ G++ + LD+++ ++ + A D+G + VQ+N I D N+ PV Sbjct: 507 TTFVSLDADSGVLRAVRSLDYEKLKQLDFEIEAADNGIPQLSTRVQLNLRIVDQNDNCPV 566 Query: 469 FENAPYTASVFE-----DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523 N E AP V + A DSD G N+Q+ Y++ + S + Sbjct: 567 ITNPLLNNGSGEVLLPISAPQNYLVFQLKAEDSDEGHNSQLFYTILRDPS--------RL 618 Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 F IN ++G + K L+ + + V D G PSLS V+ + D Sbjct: 619 FAINKESGEVFLKKQLNSDHSEDLSIVVAVYDLGRPSLSTNATVKFILTD 668 Score = 155 bits (375), Expect = 2e-35 Identities = 154/574 (26%), Positives = 254/574 (44%), Gaps = 47/574 (8%) Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS---ITSQNGRGLITVA 426 QY ++ E+EPPGT + L+ N T +F+ I + G +++ Sbjct: 26 QYYID--EEEPPGTVIAVLSQHSIF--NTTDIPATNFRLMKQFNNSLIGVRESDGQLSIM 81 Query: 427 QPLDFKQERRYVLTVS-ATD----SGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 + +D +Q R L + A D S G V++ + D N+++P F + V E Sbjct: 82 ERIDREQICRQSLHCNLALDVVSFSKGHFKLLNVKVEVRDINDHSPHFPSEIMHVEVSES 141 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLS--SEISNEAVAHHDQQFVINPQTGAITTNKLL 539 + +GT + + A D DVG N+ + +S S S + + D + + + L Sbjct: 142 SSVGTRIPLEIAIDEDVGSNSIQNFQISNNSHFSIDVLTRAD-----GVKYADLVLMREL 196 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 DRE Y++ + A DGGVPSLS T V I V+D NDN PVF++ +++EDA +G Sbjct: 197 DREIQPTYIMELLAMDGGVPSLSGTAVVNIRVLDFNDNSPVFERSTIAVDLVEDAPLGYL 256 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREE--GSFVIDPASGVIRTNKALDRESVATHDLKA 657 + ++ ATD D G+NG I Y +E F I+ +G + +D E+ T++ + Sbjct: 257 LLELHATDDDEGVNGEIVYGFSTLASQEVRQLFKINSRTGSVTLEGQVDFETKQTYEFEV 316 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT------FYISENSPIGTTIGEIRA 711 A D G P ++T V + I D+ND+ P LT YI E + I I Sbjct: 317 QAQDLGPNPLTATCKVTVHILDVNDNTPAITITPLTTVNAGVAYIPETATKENFIALIST 376 Query: 712 HDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771 D G N V ++ G + F L+ + D +VT LD E+ Y L + A Sbjct: 377 TDRASGSNGQVRCTLYGHE---HFKLQ-QAYEDSYMIVTTSTLDREN-IAAYSLTVVAED 431 Query: 772 ---PPLWNDVRVEILVTDVNDNAPVMK----DFQIIFNNYKDCFPVGPFGRVPAYDADVT 824 P L + V+D NDNAPV + I+ NN + R D+D Sbjct: 432 LGFPSLKTKKYYTVKVSDENDNAPVFSKPQYEASILENNAPGSYITTVIAR--DSDSDQN 489 Query: 825 DKLQYR-----ILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKA 878 K+ YR ++ + + L+ +G + L+ K E+ D G+ ++ Sbjct: 490 GKVNYRLVDAKVMGQSLTTFVSLDADSGVLRAVRSLDYEKLKQLDFEIEAADNGIPQLST 549 Query: 879 MMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPL 912 +QL++R++ + IT L + + + L P+ Sbjct: 550 RVQLNLRIVDQNDNCPVITNPLLNNGSGEVLLPI 583 Score = 134 bits (324), Expect = 3e-29 Identities = 128/466 (27%), Positives = 199/466 (42%), Gaps = 36/466 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I VLD ND+SPVFE + E A G +L L ATD D G N E+ Y TL Sbjct: 226 IRVLDFNDNSPVFERSTIAVDLVEDAPLGYLLLELHATDDDEGVNGEIVYGFS-----TL 280 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 ++ V+ +F+I+ R+G++ +D E Y V+A D + L Sbjct: 281 ASQE-----------VRQLFKINSRTGSVTLEGQVDFETKQTYEFEVQAQDLGP---NPL 326 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS-----VTDNPVIAKIKATDADVGANS 185 ++T + V+I+D NDN P + T +V+ ++ T IA I TD G+N Sbjct: 327 TATCKVTVHILDVNDNTPAITITPLT-TVNAGVAYIPETATKENFIALISTTDRASGSNG 385 Query: 186 AIRYAIIGG-NTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 +R + G + ++Q + + S + TLD E + +Y L + A+D G PS Sbjct: 386 QVRCTLYGHEHFKLQQAYED-SYMIVTTSTLDRENIAAYSLTVVAEDLGFPSLKTKKYYT 444 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG- 303 + + D NDNAP F ++ S+ EN G I V A D+D N ++ Y + D G Sbjct: 445 VKVSDENDNAPVFSKPQYEASILENNAPGSYITTVIARDSDSDQNGKVNYRLVDAKVMGQ 504 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX---- 359 ++ +++D SG + LD E + + A D G P S Sbjct: 505 SLTTFVSLDADSGVLRAVRSLDYEKLKQLDFEIEAADNGIPQLSTRVQLNLRIVDQNDNC 564 Query: 360 -XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITS 416 G EV L P V L A D+DE +++L Y I +R F+I Sbjct: 565 PVITNPLLNNGSGEVLLPISAPQNYLVFQLKAEDSDEGHNSQLFYTILRDPSR-LFAINK 623 Query: 417 QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDA 462 ++G + D ++ V+ V S A V+ +TD+ Sbjct: 624 ESGEVFLKKQLNSDHSEDLSIVVAVYDLGRPSLSTNATVKFILTDS 669 Score = 99.5 bits (237), Expect = 1e-18 Identities = 82/272 (30%), Positives = 127/272 (46%), Gaps = 27/272 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D ND++PVF QYEAS+ E + G+ + T+ A D D +N +V Y LV A + Sbjct: 445 VKVSDENDNAPVFSKPQYEASILENNAPGSYITTVIARDSDSDQNGKVNY--RLVDAKVM 502 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + +D SG L SLD EK+ + ++A D P +L Sbjct: 503 GQS------------LTTFVSLDADSGVLRAVRSLDYEKLKQLDFEIEAADNGIP---QL 547 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDE---DISVTDNPVIAKIKATDADVGANSAI 187 S+ +++ I+D NDN P + E IS N ++ ++KA D+D G NS + Sbjct: 548 STRVQLNLRIVDQNDNCPVITNPLLNNGSGEVLLPISAPQNYLVFQLKAEDSDEGHNSQL 607 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS-NTTQLLIN 246 Y I+ +++ F+I+ SG+V L K L+ + +V+ D G PS S N T I Sbjct: 608 FYTILRDPSRL-FAINKESGEVFLKKQLNSDHSEDLSIVVAVYDLGRPSLSTNATVKFI- 665 Query: 247 IRDVNDNAP-RFYTSLFQESVSENVPIGYSIV 277 + D+ P + Q S E I SI+ Sbjct: 666 ---LTDSFPSNVEVVILQPSAEEQHQIDMSII 694 >UniRef50_Q6EI13 Cluster: GammaA-like protocadherin precursor; n=5; Gallus gallus|Rep: GammaA-like protocadherin precursor - Gallus gallus (Chicken) Length = 811 Score = 203 bits (496), Expect = 5e-50 Identities = 162/549 (29%), Positives = 244/549 (44%), Gaps = 23/549 (4%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F + SG L+T +DRE++ R +L K + + + I V I D NDN P Sbjct: 76 FVLHASSGHLVTAERIDREQLCR--LLEKCVLRCELIVEGEMKVYPIEVEITDINDNTPS 133 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG---NTQMQFSIDSLS 206 F E + +E + + + A D D+G NS YA+ G + +Q D Sbjct: 134 FGEGQIELRTNEMAVIGMRYALRR--AHDPDMGTNSLQSYALSGDEHFSLSVQAGADGEK 191 Query: 207 G-DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265 ++ L K LD E+ + L++RA DGG P+R+ T ++ + + D NDNAP F +++ Sbjct: 192 RPELVLAKALDREEAAFHELLLRASDGGDPARTGTARIRVAVLDANDNAPAFSQAVYTVR 251 Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325 V E+VP+G +++RV A D D+G N ++ Y ++ + I+P++G + LD Sbjct: 252 VPEDVPVGSTLLRVTATDPDDGTNGDVKYLF--QEVLEQISNTFHIEPKTGAIRLVRNLD 309 Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 E Y+ LV A DGG A T E+ +ED PGT V Sbjct: 310 FEEADFYEFLVQAHDGGGLSDDAKITVSVTDVNDNAPEISVRSALSEI--SEDAAPGTVV 367 Query: 386 VTLTATDADEDNRLHYEIT-GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444 L D D + G R + ++T A+ LD ++ Y +TV A Sbjct: 368 ALLHVQDRDSGANGEVRCSLGEGVPFRLERALDDYYSVVT-ARELDRERASEYNVTVRAA 426 Query: 445 DSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502 D G + A++ + + D N+ APVF A Y+A + E+ G VL V A D+D G NA Sbjct: 427 DGGSPALRSGAVLALRVLDVNDNAPVFAEARYSARLPENNAEGALVLTVRAWDADWGQNA 486 Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 ++ Y L A + +TGA+ + D E + L V A DGG P LS Sbjct: 487 RVRYRLRE--GRLRGAPLSSYVSVQAETGALYALRSFDYEEVREVELWVRAEDGGAPPLS 544 Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP 622 V + + D NDN P Q LY S + VGA + G EL P Sbjct: 545 SNVSVRLLIADENDNAP---QVLYPPAAPGPG--PGSGAGVGAWGSASGAWSWAGVELAP 599 Query: 623 KDREEGSFV 631 + E G+ V Sbjct: 600 RSAEPGALV 608 Score = 202 bits (492), Expect = 1e-49 Identities = 147/440 (33%), Positives = 215/440 (48%), Gaps = 25/440 (5%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLH-YEITGGNTRGRFSITSQNG---- 419 F GQ E+ E G A D D N L Y ++G FS++ Q G Sbjct: 134 FGEGQIELRTNEMAVIGMRYALRRAHDPDMGTNSLQSYALSGDE---HFSLSVQAGADGE 190 Query: 420 -RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTA 476 R + +A+ LD ++ + L + A+D G R+ TA +++ + DAN+ AP F A YT Sbjct: 191 KRPELVLAKALDREEAAFHELLLRASDGGDPARTGTARIRVAVLDANDNAPAFSQAVYTV 250 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 V ED P+G+T+L V+ATD D G N + Y + E + F I P+TGAI Sbjct: 251 RVPEDVPVGSTLLRVTATDPDDGTNGDVKY-----LFQEVLEQISNTFHIEPKTGAIRLV 305 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 + LD E Y V A DGG LSD + +SV DVNDN P + + I EDA Sbjct: 306 RNLDFEEADFYEFLVQAHDGG--GLSDDAKITVSVTDVNDNAPEISVRSALSEISEDAAP 363 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 GT V+ + D D G NG + L +D V+ T + LDRE + +++ Sbjct: 364 GTVVALLHVQDRDSGANGEVRCSLGEGVPFRLERALDDYYSVV-TARELDRERASEYNVT 422 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 A DGG+P S ++ +++ D+ND+ PVF + + EN+ G + +RA D D Sbjct: 423 VRAADGGSPALRSGAVLALRVLDVNDNAPVFAEARYSARLPENNAEGALVLTVRAWDADW 482 Query: 717 GPNAVVHYSIKGGDDSNS-FSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASP 772 G NA V Y ++ G + S ++ L + DYE R + EL +RA +P Sbjct: 483 GQNARVRYRLREGRLRGAPLSSYVSVQAETGALYALRSFDYEEVR-EVELWVRAEDGGAP 541 Query: 773 PLWNDVRVEILVTDVNDNAP 792 PL ++V V +L+ D NDNAP Sbjct: 542 PLSSNVSVRLLIADENDNAP 561 Score = 158 bits (383), Expect = 2e-36 Identities = 119/386 (30%), Positives = 184/386 (47%), Gaps = 16/386 (4%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 +++ ITD N+ P F E A IG + A D D+G N+ +Y+LS + Sbjct: 120 IEVEITDINDNTPSFGEGQIELRTNEMAVIGMRYALRRAHDPDMGTNSLQSYALSGD--- 176 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 E + Q + + K LDRE + + L + A DGG P+ + T + ++V+D Sbjct: 177 EHFSLSVQAGADGEKRPELVLAKALDREEAAFHELLLRASDGGDPARTGTARIRVAVLDA 236 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFVID 633 NDN P F Q +YT + ED VG+++ +V ATD D G NG + Y + ++ +F I+ Sbjct: 237 NDNAPAFSQAVYTVRVPEDVPVGSTLLRVTATDPDDGTNGDVKYLFQEVLEQISNTFHIE 296 Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693 P +G IR + LD E ++ A DGG + + V + D+ND+ P Sbjct: 297 PKTGAIRLVRNLDFEEADFYEFLVQAHDGGGLSDDAKITV--SVTDVNDNAPEISVRSAL 354 Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753 ISE++ GT + + D D G N V S+ G F LE R D +VT + Sbjct: 355 SEISEDAAPGTVVALLHVQDRDSGANGEVRCSLGEGVP---FRLE-RALDDYYSVVTARE 410 Query: 754 LDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV 810 LD E +Y + +RAA SP L + + + V DVNDNAPV + + ++ Sbjct: 411 LDRERA-SEYNVTVRAADGGSPALRSGAVLALRVLDVNDNAPVFAEARYSARLPENNAEG 469 Query: 811 GPFGRVPAYDAD--VTDKLQYRILSG 834 V A+DAD +++YR+ G Sbjct: 470 ALVLTVRAWDADWGQNARVRYRLREG 495 Score = 153 bits (371), Expect = 7e-35 Identities = 104/344 (30%), Positives = 168/344 (48%), Gaps = 27/344 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ VLD ND++P F Y V E G+T+L + ATD D G N +V+Y + V Sbjct: 230 RVAVLDANDNAPAFSQAVYTVRVPEDVPVGSTLLRVTATDPDDGTNGDVKYLFQEVLEQ- 288 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + + F I+ ++GA+ +LD E+ Y LV+A D Sbjct: 289 ----------------ISNTFHIEPKTGAIRLVRNLDFEEADFYEFLVQAHDGGG----- 327 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LS A I V++ D NDN P+ S ++ + ED V+A + D D GAN +R Sbjct: 328 LSDDAKITVSVTDVNDNAPEISVRSALSEISED--AAPGTVVALLHVQDRDSGANGEVRC 385 Query: 190 AI-IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 ++ G +++ ++D V+ + LD E+ Y + +RA DGGSP+ + L + + Sbjct: 386 SLGEGVPFRLERALDDYYSVVT-ARELDRERASEYNVTVRAADGGSPALRSGAVLALRVL 444 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-NVDL 307 DVNDNAP F + + + EN G ++ V+A+DAD G NA + Y + + G + Sbjct: 445 DVNDNAPVFAEARYSARLPENNAEGALVLTVRAWDADWGQNARVRYRLREGRLRGAPLSS 504 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 +++ +G +Y D E + +L V A DGG PP S+ + Sbjct: 505 YVSVQAETGALYALRSFDYEEVREVELWVRAEDGGAPPLSSNVS 548 Score = 124 bits (300), Expect = 3e-26 Identities = 90/279 (32%), Positives = 135/279 (48%), Gaps = 14/279 (5%) Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVNDNEPV 580 Q FV++ +G + T + +DRE + L R + V +E+ + D+NDN P Sbjct: 74 QYFVLHASSGHLVTAERIDREQLCRLLEKCVLRCELIVEGEMKVYPIEVEITDINDNTPS 133 Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640 F + E A++G + A D D+G N Y L D V A G R Sbjct: 134 FGEGQIELRTNEMAVIGMRYALRRAHDPDMGTNSLQSYALSG-DEHFSLSVQAGADGEKR 192 Query: 641 TN----KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696 KALDRE A H+L A DGG P ++ T + + + D ND+ P F T + Sbjct: 193 PELVLAKALDREEAAFHELLLRASDGGDPARTGTARIRVAVLDANDNAPAFSQAVYTVRV 252 Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG--GDDSNSFSLETRQGSDKAELVTMVDL 754 E+ P+G+T+ + A DPD+G N V Y + SN+F +E + G+ LV +L Sbjct: 253 PEDVPVGSTLLRVTATDPDDGTNGDVKYLFQEVLEQISNTFHIEPKTGA--IRLVR--NL 308 Query: 755 DYESPRKKYELVIRA-ASPPLWNDVRVEILVTDVNDNAP 792 D+E YE +++A L +D ++ + VTDVNDNAP Sbjct: 309 DFEE-ADFYEFLVQAHDGGGLSDDAKITVSVTDVNDNAP 346 >UniRef50_UPI0000E80EAB Cluster: PREDICTED: similar to Protocadherin beta 15 precursor (PCDH-beta15); n=6; Gallus gallus|Rep: PREDICTED: similar to Protocadherin beta 15 precursor (PCDH-beta15) - Gallus gallus Length = 927 Score = 203 bits (495), Expect = 6e-50 Identities = 144/501 (28%), Positives = 230/501 (45%), Gaps = 23/501 (4%) Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV----RSYRLVIRAQDGGSPSRSNT 240 +A + ++ ++ F +D SG +++ +TLD E++ S L+ + N Sbjct: 418 AARKARVVSEGSEQHFRLDPHSGVLTVTETLDRERICPHSESCALLFKL------FFENP 471 Query: 241 TQLL---INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297 QL+ + +RDVND++P F V E G A D D G+N Y+++ Sbjct: 472 VQLIRGEVEVRDVNDHSPVFPQKEVVLEVLETASPGSRFSLESAQDEDVGINGLQNYSLS 531 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357 Y + LDRE Q + L++TATDGG PPRS TA Sbjct: 532 PNPYFSLALEKWKGGAEFVKLVLQKPLDREEQRELHLVLTATDGGSPPRSGTAQVRVVVL 591 Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSIT 415 F YEV +AE+ PPG VV ++A D DE + ++ Y T + + + Sbjct: 592 DANDNMPVFSREVYEVRVAENSPPGQLVVRVSAADPDEGSNGKVRYTFTEMSEQSQQLYE 651 Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYT 475 G I V+ LD+++E+ + L V A D GG S V + + D N+ AP + + Sbjct: 652 LNPETGEIRVSGNLDYEEEKMHELVVRAMDGGGLSAHCRVHVEVLDVNDNAPEIALSSVS 711 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 AS+ EDAP T V ++S D D G N + ++ ++ A + + T Sbjct: 712 ASIPEDAPPRTVVALLSVRDRDSGDNGRTECAIEGDVPFSLTAAFANHYELR-------T 764 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 + LDRET + Y +++ A D G LS V + + DVNDN P F Q Y+ ++ E+ Sbjct: 765 SAALDRETTAEYNVSIVATDWGRARLSARESVSVRIADVNDNAPRFTQAAYSMSVSENEA 824 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV-IDPASGVIRTNKALDRESVATHD 654 + V ATDAD G NGR+ Y L ++ EE V + S + +++D + V Sbjct: 825 GAVRIGSVKATDADAGANGRVRYALVREEGEERPDVSLYAESRPLSVVRSVDIDDVGAVK 884 Query: 655 LKAVAIDGGTPPQSSTVIVHI 675 GG+PP+S+ ++ + Sbjct: 885 ATLRTAKGGSPPRSAATLLRL 905 Score = 171 bits (415), Expect = 3e-40 Identities = 116/353 (32%), Positives = 173/353 (49%), Gaps = 10/353 (2%) Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480 + + +PLD +++R L ++ATD G RS TA V++ + DAN+ PVF Y V E Sbjct: 552 LVLQKPLDREEQRELHLVLTATDGGSPPRSGTAQVRVVVLDANDNMPVFSREVYEVRVAE 611 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 ++P G V+ VSA D D G N ++ Y+ + E+S ++ Q + +NP+TG I + LD Sbjct: 612 NSPPGQLVVRVSAADPDEGSNGKVRYTFT-EMSEQS----QQLYELNPETGEIRVSGNLD 666 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 E + L V A DGG LS V + V+DVNDN P +A+I EDA T V Sbjct: 667 YEEEKMHELVVRAMDGG--GLSAHCRVHVEVLDVNDNAPEIALSSVSASIPEDAPPRTVV 724 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 + + D D G NGR ++ D +RT+ ALDRE+ A +++ VA Sbjct: 725 ALLSVRDRDSGDNGRTECAIEG-DVPFSLTAAFANHYELRTSAALDRETTAEYNVSIVAT 783 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 D G S+ V ++I D+ND+ P F + +SEN IG ++A D D G N Sbjct: 784 DWGRARLSARESVSVRIADVNDNAPRFTQAAYSMSVSENEAGAVRIGSVKATDADAGANG 843 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP 773 V Y++ + + S +V VD+D K + SPP Sbjct: 844 RVRYALVREEGEERPDVSLYAESRPLSVVRSVDIDDVGAVKATLRTAKGGSPP 896 Score = 170 bits (413), Expect = 5e-40 Identities = 141/489 (28%), Positives = 212/489 (43%), Gaps = 33/489 (6%) Query: 90 FRIDGRSGALLTRASLDREKVARYT---VLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146 FR+D SG L +LDRE++ ++ L+ +PV V + D ND+ Sbjct: 433 FRLDPHSGVLTVTETLDRERICPHSESCALLFKLFFENPVQ-----LIRGEVEVRDVNDH 487 Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLS 206 P F +K + V E S + A D DVG N Y++ N +++ Sbjct: 488 SPVFPQKEVVLEVLETASPGSR--FSLESAQDEDVGINGLQNYSL-SPNPYFSLALEKWK 544 Query: 207 GDVSLVKT-----LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261 G VK LD E+ R LV+ A DGGSP RS T Q+ + + D NDN P F + Sbjct: 545 GGAEFVKLVLQKPLDREEQRELHLVLTATDGGSPPRSGTAQVRVVVLDANDNMPVFSREV 604 Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321 ++ V+EN P G +VRV A D DEG N ++ YT T + + ++P +G + S Sbjct: 605 YEVRVAENSPPGQLVVRVSAADPDEGSNGKVRYTFT--EMSEQSQQLYELNPETGEIRVS 662 Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381 G LD E + ++L+V A DGG SA + ED PP Sbjct: 663 GNLDYEEEKMHELVVRAMDGGG--LSAHCRVHVEVLDVNDNAPEIALSSVSASIPEDAPP 720 Query: 382 GTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGL-ITVAQPLDFKQERRYV 438 T V L+ D D ++ R I G FS+T+ + + LD + Y Sbjct: 721 RTVVALLSVRDRDSGDNGRTECAIEGDVP---FSLTAAFANHYELRTSAALDRETTAEYN 777 Query: 439 LTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496 +++ ATD G S V + I D N+ AP F A Y+ SV E+ + V ATD+ Sbjct: 778 VSIVATDWGRARLSARESVSVRIADVNDNAPRFTQAAYSMSVSENEAGAVRIGSVKATDA 837 Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556 D G N ++ Y+L E E + ++ ++ + +D + + T+ G Sbjct: 838 DAGANGRVRYALVREEGEER-----PDVSLYAESRPLSVVRSVDIDDVGAVKATLRTAKG 892 Query: 557 GVPSLSDTT 565 G P S T Sbjct: 893 GSPPRSAAT 901 Score = 158 bits (384), Expect = 2e-36 Identities = 116/374 (31%), Positives = 177/374 (47%), Gaps = 20/374 (5%) Query: 456 QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515 ++ + D N+++PVF V E A G+ + SA D DVGIN YSLS N Sbjct: 478 EVEVRDVNDHSPVFPQKEVVLEVLETASPGSRFSLESAQDEDVGINGLQNYSLSP---NP 534 Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575 + +++ + + K LDRE L +TA DGG P S T V + V+D N Sbjct: 535 YFSLALEKWKGGAEFVKLVLQKPLDREEQRELHLVLTATDGGSPPRSGTAQVRVVVLDAN 594 Query: 576 DNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFVIDP 634 DN PVF +++Y + E++ G V +V A D D G NG++ Y + ++ + + ++P Sbjct: 595 DNMPVFSREVYEVRVAENSPPGQLVVRVSAADPDEGSNGKVRYTFTEMSEQSQQLYELNP 654 Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694 +G IR + LD E H+L A+DGG S+ VH+++ D+ND+ P ++ Sbjct: 655 ETGEIRVSGNLDYEEEKMHELVVRAMDGGG--LSAHCRVHVEVLDVNDNAPEIALSSVSA 712 Query: 695 YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDL 754 I E++P T + + D D G N +I+G FSL T ++ EL T L Sbjct: 713 SIPEDAPPRTVVALLSVRDRDSGDNGRTECAIEG---DVPFSL-TAAFANHYELRTSAAL 768 Query: 755 DYESPRKKYELVIRAASPPLWNDVR------VEILVTDVNDNAPVMKDFQIIFNNYKDCF 808 D E+ + Y + I A W R V + + DVNDNAP + ++ Sbjct: 769 DRETTAE-YNVSIVATD---WGRARLSARESVSVRIADVNDNAPRFTQAAYSMSVSENEA 824 Query: 809 PVGPFGRVPAYDAD 822 G V A DAD Sbjct: 825 GAVRIGSVKATDAD 838 Score = 155 bits (376), Expect = 2e-35 Identities = 117/416 (28%), Positives = 189/416 (45%), Gaps = 39/416 (9%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 I ++ V D NDHSPVF ++ V E AS G+ A D+D+G N Y++ Sbjct: 475 IRGEVEVRDVNDHSPVFPQKEVVLEVLETASPGSRFSLESAQDEDVGINGLQNYSL---- 530 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 + NP + ++ L+ + LDRE+ +++ ATD SP Sbjct: 531 --SPNP---------YFSLALEKWKGGAEFVKLVLQKPLDREEQRELHLVLTATDGGSPP 579 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 S TA + V ++D NDN P FS + Y V V E + ++ ++ A D D G+N Sbjct: 580 R---SGTAQVRVVVLDANDNMPVFSREVYEVRVAE--NSPPGQLVVRVSAADPDEGSNGK 634 Query: 187 IRYAI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 +RY + +Q + ++ +G++ + LDYE+ + + LV+RA DGG S ++ Sbjct: 635 VRYTFTEMSEQSQQLYELNPETGEIRVSGNLDYEEEKMHELVVRAMDGGGLSAH--CRVH 692 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + + DVNDNAP S S+ E+ P + + D D G N T+ G+ Sbjct: 693 VEVLDVNDNAPEIALSSVSASIPEDAPPRTVVALLSVRDRDSGDNGR-----TECAIEGD 747 Query: 305 VDLPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 V +T + + + TS LDRET A+Y + + ATD G SA + Sbjct: 748 VPFSLTAAFANHYELRTSAALDRETTAEYNVSIVATDWGRARLSARESVSVRIADVNDNA 807 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNG 419 F Y + ++E+E + ++ ATDAD G N R R+++ + G Sbjct: 808 PRFTQAAYSMSVSENEAGAVRIGSVKATDAD---------AGANGRVRYALVREEG 854 Score = 135 bits (326), Expect = 2e-29 Identities = 103/342 (30%), Positives = 158/342 (46%), Gaps = 32/342 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ VLD ND+ PVF + YE V E + G V+ + A D D G N +V YT ++ + Sbjct: 587 RVVVLDANDNMPVFSREVYEVRVAENSPPGQLVVRVSAADPDEGSNGKVRYTFTEMSEQS 646 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 Q ++ ++ +G + +LD E+ + ++V+A D Sbjct: 647 -----------------QQLYELNPETGEIRVSGNLDYEEEKMHELVVRAMDGGG----- 684 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 LS+ +HV ++D NDN P+ + + + S+ ED V+A + D D G N Sbjct: 685 LSAHCRVHVEVLDVNDNAPEIALSSVSASIPED--APPRTVVALLSVRDRDSGDNGRTEC 742 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 AI G + FS+ + + ++T LD E Y + I A D G S + + Sbjct: 743 AIEG---DVPFSLTAAFANHYELRTSAALDRETTAEYNVSIVATDWGRARLSARESVSVR 799 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 I DVNDNAPRF + + SVSEN I V+A DAD G N + Y + ++ D Sbjct: 800 IADVNDNAPRFTQAAYSMSVSENEAGAVRIGSVKATDADAGANGRVRYALVREEGEERPD 859 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348 + + + R V S +D + A L TA GG PPRSA Sbjct: 860 VSLYAESRPLSVVRSVDID-DVGAVKATLRTA-KGGSPPRSA 899 Score = 81.4 bits (192), Expect = 3e-13 Identities = 81/285 (28%), Positives = 125/285 (43%), Gaps = 16/285 (5%) Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGS---FVIDPASGVIRTNKALDRESVATHDLK- 656 S VG D+GL+ + EGS F +DP SGV+ + LDRE + H Sbjct: 401 SLVGNVAQDLGLSPSQLAARKARVVSEGSEQHFRLDPHSGVLTVTETLDRERICPHSESC 460 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 A+ + +++ D+ND PVF + + E + G+ A D D Sbjct: 461 ALLFKLFFENPVQLIRGEVEVRDVNDHSPVFPQKEVVLEVLETASPGSRFSLESAQDEDV 520 Query: 717 GPNAVVHYSIKGGDDSNSFSLET-RQGSDKAELVTMVDLDYESPRKKYELVIRAA---SP 772 G N + +YS+ + S +LE + G++ +LV LD E R+ + LV+ A SP Sbjct: 521 GINGLQNYSLSP-NPYFSLALEKWKGGAEFVKLVLQKPLDREEQRELH-LVLTATDGGSP 578 Query: 773 PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPF-GRVPAYDAD--VTDKLQY 829 P +V ++V D NDN PV ++ + P G RV A D D K++Y Sbjct: 579 PRSGTAQVRVVVLDANDNMPVFSR-EVYEVRVAENSPPGQLVVRVSAADPDEGSNGKVRY 637 Query: 830 RI--LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 +S + L LN TG + +S L+ K+ + V DG Sbjct: 638 TFTEMSEQSQQLYELNPETGEIRVSGNLDYEEEKMHELVVRAMDG 682 >UniRef50_UPI00015B46FC Cluster: PREDICTED: similar to CG14900-PA; n=1; Nasonia vitripennis|Rep: PREDICTED: similar to CG14900-PA - Nasonia vitripennis Length = 2225 Score = 202 bits (494), Expect = 8e-50 Identities = 212/823 (25%), Positives = 365/823 (44%), Gaps = 92/823 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-LKATDQDIGK--NAEVEYTIELVTA 67 + V D NDH+P F Y +V E +G T+ + A D+D N++V Y I Sbjct: 370 VYVEDVNDHAPQFVDAPYHVTVDELTPTGLTIFRGIHAFDKDKPNTPNSDVHYAI----- 424 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRID-GRSGALLTRASLDREKVAR-YTVLVKATDQASP 125 Q F ++ G AL+ R LD + R Y +++ A D+ +P Sbjct: 425 --------------IKGNEQGKFSLESGHRTALILRKPLDYDIGDREYVLIISANDRGTP 470 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV------IAKIKATDA 179 S+ TI + ++D++D P+F+++ Y + E + +P+ I+A D Sbjct: 471 PK---STNTTITITVVDNDDLDPKFTQEVYRTEIFEFYPMPSHPIHKEIEFATPIRAIDQ 527 Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-----YRLVIRAQDGGS 234 D + + Y II GN + F +D +G + L + +D + R+ + L I A + Sbjct: 528 DRDIDVPVLYDIISGNERGLFHLDPRNGTLFLDRAIDLDAERNLPGNTFVLQIHASQIDN 587 Query: 235 PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294 P + + ++ + + D+NDN P F + S+ EN+P G+S+++V AYD D+GVN E TY Sbjct: 588 PLKVASARVEVEVLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVIAYDRDQGVNGEFTY 647 Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGGDP-----PRS 347 + D +G ++DP SGW+ Q LDRE ++ Q+ V A + S Sbjct: 648 ELNDP--SG----AFSVDPISGWLTVQDQSVLDREQKSFLQMKVLAVEKQPSVVKPYNGS 701 Query: 348 ATATXXXXXXXXXXXXXXFMPGQ-YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEI- 403 ++ F+PG E+ D GT + + A D D + + Y++ Sbjct: 702 SSVEVEVTLLDANDNNPVFVPGNLLELVAQSDFKVGTILGQVHAVDNDLGTNGLVRYKLQ 761 Query: 404 TGGNTRGRFSITSQNGRGLITVA-QPLDFKQERRYVLTVSATD-----SGGRSDTAMVQI 457 GN G+ + G+ITVA P+ E R+ + + A D S R A+V I Sbjct: 762 RPGNFTGKMPFAVNSDTGVITVADSPI---LEGRHAIFIEAADQPANPSERRFSLAVVTI 818 Query: 458 NI-TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA 516 ++ + AP F APY V + P+GT+V + ++ G ++ Y L Sbjct: 819 DVFRPEGSKAPDFIGAPYEFWVGANVPVGTSVGQIRVNEAVNG--NEVVYDLLHSY---- 872 Query: 517 VAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVND 576 H F + ++G IT ++R S Y + SLS T+V I VVD ND Sbjct: 873 --HEGVPFAVEERSGTITVVDEIERYKQSSYDFEAVVTN--EKSLSLVTNVSIHVVDPND 928 Query: 577 NEPVFKQQLYTANI---MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID 633 +F + A + + + G + V +A L +H+ + ++++ + + Sbjct: 929 ESGIFAKGTTKAPLVFHVRENAAGAFIGHVVPANASDSLK-NVHFLI--ANQQDVAEIAI 985 Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693 +GV+ T L+RE + L A+A +P V I ++D +D+ P+F + Sbjct: 986 TDTGVLYTPTGLNREKRQNYSLTAIA---ESPRGVGVFQVMIIVDDEDDNAPIFSASAYE 1042 Query: 694 FYISENSPIGTTI---GEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750 ISENS GT + + A DPDE + + ++++ G+ S+ F ++ G + Sbjct: 1043 GRISENSQTGTEVIMTNHVSARDPDEDSSFM--FTLR-GEGSDLFRIDRNTGR-VFFIGN 1098 Query: 751 MVDLDYESPRKKYEL-VIRAASPPLWNDVRVEILVTDVNDNAP 792 +L + Y L ++ ++V + I V D NDN P Sbjct: 1099 ATELLDREEKPLYNLQIVAGERKKKSSNVSLTIHVDDENDNPP 1141 Score = 171 bits (417), Expect = 2e-40 Identities = 167/606 (27%), Positives = 266/606 (43%), Gaps = 56/606 (9%) Query: 223 YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR-VQA 281 +RL DG S+ + + + DVND+AP+F + + +V E P G +I R + A Sbjct: 348 FRLGCDYSDGSDSLVSSHLSVTVYVEDVNDHAPQFVDAPYHVTVDELTPTGLTIFRGIHA 407 Query: 282 YDADE--GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET-QAKYQLLVTA 338 +D D+ N+++ Y + + G L R+ + LD + +Y L+++A Sbjct: 408 FDKDKPNTPNSDVHYAIIKGNEQGKFSL--ESGHRTALILRK-PLDYDIGDREYVLIISA 464 Query: 339 TDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP-PGTPV-------VTLTA 390 D G PP+S T F Y E+ E P P P+ + A Sbjct: 465 NDRGTPPKSTNTTITITVVDNDDLDPKFTQEVYRTEIFEFYPMPSHPIHKEIEFATPIRA 524 Query: 391 TDADEDNRLH--YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE---RRYVLTVSAT- 444 D D D + Y+I GN RG F + +NG + A LD ++ +VL + A+ Sbjct: 525 IDQDRDIDVPVLYDIISGNERGLFHLDPRNGTLFLDRAIDLDAERNLPGNTFVLQIHASQ 584 Query: 445 -DSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503 D+ + +A V++ + D N+ P FE Y S+ E+ P G +VL V A D D G+N + Sbjct: 585 IDNPLKVASARVEVEVLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVIAYDRDQGVNGE 644 Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITT--NKLLDRETMSGYLLTVTARDGGVPSL 561 TY L+ F ++P +G +T +LDRE S + V A + PS+ Sbjct: 645 FTYELNDP---------SGAFSVDPISGWLTVQDQSVLDREQKSFLQMKVLAVE-KQPSV 694 Query: 562 ------SDTTDVEISVVDVNDNEPVF-KQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614 S + +VE++++D NDN PVF L D VGT + QV A D D+G NG Sbjct: 695 VKPYNGSSSVEVEVTLLDANDNNPVFVPGNLLELVAQSDFKVGTILGQVHAVDNDLGTNG 754 Query: 615 RIHYELDPKDREEGS--FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS---S 669 + Y+L G F ++ +GVI + E H + A D P S Sbjct: 755 LVRYKLQRPGNFTGKMPFAVNSDTGVITVADSPILE--GRHAIFIEAADQPANPSERRFS 812 Query: 670 TVIVHIKI-EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 +V I + P F F++ N P+GT++G+IR ++ G N VV+ + Sbjct: 813 LAVVTIDVFRPEGSKAPDFIGAPYEFWVGANVPVGTSVGQIRVNEAVNG-NEVVYDLLHS 871 Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL-VIRAASPPLWNDVRVEILVTDV 787 + F++E R G+ +T+VD + Y+ + L V I V D Sbjct: 872 YHEGVPFAVEERSGT-----ITVVDEIERYKQSSYDFEAVVTNEKSLSLVTNVSIHVVDP 926 Query: 788 NDNAPV 793 ND + + Sbjct: 927 NDESGI 932 Score = 169 bits (412), Expect = 7e-40 Identities = 196/760 (25%), Positives = 321/760 (42%), Gaps = 65/760 (8%) Query: 127 SDRL-SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV--GA 183 SD L SS ++ V + D ND+ PQF + Y V+VDE ++ T + I A D D Sbjct: 358 SDSLVSSHLSVTVYVEDVNDHAPQFVDAPYHVTVDE-LTPTGLTIFRGIHAFDKDKPNTP 416 Query: 184 NSAIRYAIIGGNTQMQFSIDSLSGDVSLV-KTLDYE-QVRSYRLVIRAQDGGSPSRSNTT 241 NS + YAII GN Q +FS++S ++ K LDY+ R Y L+I A D G+P +S T Sbjct: 417 NSDVHYAIIKGNEQGKFSLESGHRTALILRKPLDYDIGDREYVLIISANDRGTPPKSTNT 476 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR--------VQAYDADEGVNAELT 293 + I + D +D P+F +++ + E P+ + ++A D D ++ + Sbjct: 477 TITITVVDNDDLDPKFTQEVYRTEIFEFYPMPSHPIHKEIEFATPIRAIDQDRDIDVPVL 536 Query: 294 YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK-----YQLLVTATDGGDPPRSA 348 Y + +GN +DPR+G ++ +D + + + L + A+ +P + A Sbjct: 537 YDI----ISGNERGLFHLDPRNGTLFLDRAIDLDAERNLPGNTFVLQIHASQIDNPLKVA 592 Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNT 408 +A F Y + + E+ P G V+ + A D D+ + + Sbjct: 593 SARVEVEVLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVIAYDRDQGVNGEFTYELNDP 652 Query: 409 RGRFSITSQNGRGLITVAQPLDFKQE---RRYVLTV----SATDSGGRSDTAMVQINITD 461 G FS+ +G + LD +Q+ + VL V S S + V++ + D Sbjct: 653 SGAFSVDPISGWLTVQDQSVLDREQKSFLQMKVLAVEKQPSVVKPYNGSSSVEVEVTLLD 712 Query: 462 ANNYAPVFENAPYTASVFE-DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520 AN+ PVF V + D +GT + V A D+D+G N + Y L + Sbjct: 713 ANDNNPVFVPGNLLELVAQSDFKVGTILGQVHAVDNDLGTNGLVRYKLQRPGNFTG---- 768 Query: 521 DQQFVINPQTGAITTNKLLDRETMSG-YLLTVTARDGGVPSLSDTTDVEISVVDV----N 575 F +N TG IT + D + G + + + A D + + +DV Sbjct: 769 KMPFAVNSDTGVIT---VADSPILEGRHAIFIEAADQPANPSERRFSLAVVTIDVFRPEG 825 Query: 576 DNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA 635 P F Y + + VGTSV Q+ +A G + Y+L E F ++ Sbjct: 826 SKAPDFIGAPYEFWVGANVPVGTSVGQIRVNEAVNG--NEVVYDLLHSYHEGVPFAVEER 883 Query: 636 SGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC---- 691 SG I ++R +++D +AV + + + V +H + D ND +F Sbjct: 884 SGTITVVDEIERYKQSSYDFEAVVTNEKSLSLVTNVSIH--VVDPNDESGIFAKGTTKAP 941 Query: 692 LTFYISENSPIGTTIGE-IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750 L F++ EN+ G IG + A+ D N VH+ I D ++ +D L T Sbjct: 942 LVFHVRENA-AGAFIGHVVPANASDSLKN--VHFLIANQQDVAEIAI-----TDTGVLYT 993 Query: 751 MVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQI---IFNNYKDC 807 L+ E R+ Y L A SP +V I+V D +DNAP+ I N + Sbjct: 994 PTGLNREK-RQNYSLTAIAESPRGVGVFQVMIIVDDEDDNAPIFSASAYEGRISENSQTG 1052 Query: 808 FPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTG 847 V V A D D + L G ++L ++ TG Sbjct: 1053 TEVIMTNHVSARDPDEDSSFMF-TLRGEGSDLFRIDRNTG 1091 Score = 153 bits (372), Expect = 5e-35 Identities = 159/600 (26%), Positives = 243/600 (40%), Gaps = 77/600 (12%) Query: 32 VREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFR 91 V E + G ++ L A D D GKNAE+ Y I + + V+ F Sbjct: 1185 VPENVTIGIPIIRLVARDPDDGKNAEITYNI----LSEIGGRTSFDSKTKSSSVVKRYFV 1240 Query: 92 IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151 +D RSG + +L E + + A D L TI V+ D ND+ P F Sbjct: 1241 MDSRSGEISVAGALPAE--TDIVLEIAARDHGG-----LMDNVTIRVHAFDVNDHAPVFK 1293 Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN--TQMQFSIDSLSGDV 209 + Y V E + + +ATDAD G N+ I Y ++ N ++F + G Sbjct: 1294 QSWYLFDVPEGNFKRFE--MGRFEATDADFGDNANITYELVPTNLDNSVKFEVSRYQGTF 1351 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY----------- 258 SL LD E Y + A+DGG S++ + I+++DVNDN PRFY Sbjct: 1352 SLGGNLDRETRDLYNFKVIAKDGGKIKMSSSVDIEIHVQDVNDNPPRFYGFQEMGRLPSN 1411 Query: 259 -------------TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 ++ SV EN +G + ++ A D+D N G + Sbjct: 1412 LVDVYRKDSKQVLVPIYYASVPENSQVGTIVTKIHANDSDFAGNGNGVILFDIPHVRGQM 1471 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX---- 361 +ID + G V T G LD ETQ + L + A+D G P ++TA Sbjct: 1472 QY-FSIDNKEGLVTTVGNLDYETQNVHNLTIVASDLGSPSLTSTALLIVRILDVDEGPDE 1530 Query: 362 -XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEI--TGGNTRGRFSITSQN 418 F YEVE+ E+ P ++ L +D ++D ++ Y I G+ R FS+ +N Sbjct: 1531 PKRPVFQHRYYEVEVEENSPVPMRILDLNVSDNNKDEQIRYSIILDEGDGREHFSLDPKN 1590 Query: 419 GRGLITVAQPLDFKQERRYVLTVSA----TDSG---------GR------SDTAMVQINI 459 G L + P D + RY L V T G G+ + A + + + Sbjct: 1591 G-SLFLLTSP-DREVRDRYELKVRVDKVKTSRGMPVMIYPVVGKRLNGLGPNEAKIILKV 1648 Query: 460 TDANNYAPVFE--NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517 D N+ AP F+ P A + A G V+ V A D D G N Q+ Y + ++ Sbjct: 1649 KDVNDNAPRFKTNGRPILAVLPTSAYYGYNVIKVEAEDPDEGANGQVRYQILGGREQDS- 1707 Query: 518 AHHDQQFVINPQTGAITT--NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575 +F I+P +G + N D + G+ + T R G S +V + V+D N Sbjct: 1708 ----PKFAIDPVSGQVQAAGNFARDAGRVFGFDVKATDRAGAEDGRSSIANVFVYVLDDN 1763 Score = 148 bits (359), Expect = 2e-33 Identities = 217/908 (23%), Positives = 366/908 (40%), Gaps = 103/908 (11%) Query: 57 EVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRA-SLDREKVARYT 114 E+E+ + D D + +F +D R+G L L RA LD E+ Sbjct: 515 EIEFATPIRAIDQDRDIDVPVLYDIISGNERGLFHLDPRNGTLFLDRAIDLDAERNLPGN 574 Query: 115 VLVKATDQASPVSDRLS-STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK 173 V AS + + L ++A + V ++D NDN P+F Y +S+ E++ + + + Sbjct: 575 TFVLQI-HASQIDNPLKVASARVEVEVLDLNDNLPEFEVDFYNISIVENLP--NGFSVLQ 631 Query: 174 IKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLV--KTLDYEQVRSYRLVIRAQD 231 + A D D G N Y + + FS+D +SG +++ LD EQ ++ + A + Sbjct: 632 VIAYDRDQGVNGEFTYEL--NDPSGAFSVDPISGWLTVQDQSVLDREQKSFLQMKVLAVE 689 Query: 232 GGSPS------RSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN-VPIGYSIVRVQAYDA 284 PS S++ ++ + + D NDN P F E V+++ +G + +V A D Sbjct: 690 K-QPSVVKPYNGSSSVEVEVTLLDANDNNPVFVPGNLLELVAQSDFKVGTILGQVHAVDN 748 Query: 285 DEGVNAELTYTMTDK-DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD 343 D G N + Y + ++TG +P ++ +G + + E ++ + + A D Sbjct: 749 DLGTNGLVRYKLQRPGNFTGK--MPFAVNSDTGVITVADSPILE--GRHAIFIEAADQPA 804 Query: 344 PPR----SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRL 399 P S F+ YE + + P GT V + +A N + Sbjct: 805 NPSERRFSLAVVTIDVFRPEGSKAPDFIGAPYEFWVGANVPVGTSVGQIRVNEAVNGNEV 864 Query: 400 HYEITGGNTRG-RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN 458 Y++ G F++ ++G ITV ++ ++ Y T+ S V I+ Sbjct: 865 VYDLLHSYHEGVPFAVEERSGT--ITVVDEIERYKQSSYDFEAVVTNEKSLSLVTNVSIH 922 Query: 459 ITDANNYAPVFEN----APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 + D N+ + +F AP V E+A VV A SD N + +++ Sbjct: 923 VVDPNDESGIFAKGTTKAPLVFHVRENAAGAFIGHVVPANASDSLKNVHFLIANQQDVAE 982 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 A+ TG + T L+RE Y LT A P V I V D Sbjct: 983 IAIT----------DTGVLYTPTGLNREKRQNYSLTAIAES---PRGVGVFQVMIIVDDE 1029 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA-DVGLNGRIHYELDPKDREEGS--FV 631 +DN P+F Y I E++ GT V A D + + L R EGS F Sbjct: 1030 DDNAPIFSASAYEGRISENSQTGTEVIMTNHVSARDPDEDSSFMFTL----RGEGSDLFR 1085 Query: 632 IDPASGVI----RTNKALDRESVATHDLKAVA---------------ID--GGTPPQSST 670 ID +G + + LDRE ++L+ VA +D PP Sbjct: 1086 IDRNTGRVFFIGNATELLDREEKPLYNLQIVAGERKKKSSNVSLTIHVDDENDNPPSFVQ 1145 Query: 671 VIV----HIKI-EDINDSPP-------VFESDCLT--FYISENSPIGTTIGEIRAHDPDE 716 +++ I++ +D D P V SD + Y+ EN IG I + A DPD+ Sbjct: 1146 MVILPDQGIRVSKDKTDKDPAPTQLTSVTNSDYRSPLLYVPENVTIGIPIIRLVARDPDD 1205 Query: 717 GPNAVVHYSIKGG-DDSNSFSLETRQGSDKAELVTMVDLDYE-----SPRKKYELVIRAA 770 G NA + Y+I SF +T+ S M E + + ++V+ A Sbjct: 1206 GKNAEITYNILSEIGGRTSFDSKTKSSSVVKRYFVMDSRSGEISVAGALPAETDIVLEIA 1265 Query: 771 SPP---LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD-- 825 + L ++V + + DVND+APV K +F+ + F GR A DAD D Sbjct: 1266 ARDHGGLMDNVTIRVHAFDVNDHAPVFKQSWYLFDVPEGNFKRFEMGRFEATDADFGDNA 1325 Query: 826 KLQYRILSGNNANLIL--LNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLS 883 + Y ++ N N + ++ G+ +L L+ L +V DG +IK + Sbjct: 1326 NITYELVPTNLDNSVKFEVSRYQGTFSLGGNLDRETRDLYNFKVIAKDG-GKIKMSSSVD 1384 Query: 884 VRLITEEM 891 + + +++ Sbjct: 1385 IEIHVQDV 1392 Score = 147 bits (355), Expect = 6e-33 Identities = 130/421 (30%), Positives = 196/421 (46%), Gaps = 53/421 (12%) Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 G I+VA L E VL ++A D GG D ++++ D N++APVF+ + Y V E Sbjct: 1246 GEISVAGALP--AETDIVLEIAARDHGGLMDNVTIRVHAFDVNDHAPVFKQSWYLFDVPE 1303 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 + ATD+D G NA ITY L + +V +F ++ G + LD Sbjct: 1304 GNFKRFEMGRFEATDADFGDNANITYELVPTNLDNSV-----KFEVSRYQGTFSLGGNLD 1358 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF------------------- 581 RET Y V A+DGG +S + D+EI V DVNDN P F Sbjct: 1359 RETRDLYNFKVIAKDGGKIKMSSSVDIEIHVQDVNDNPPRFYGFQEMGRLPSNLVDVYRK 1418 Query: 582 --KQQL---YTANIMEDALVGTSVSQVGATDADVGLNGR--IHYELDPKDREEGSFVIDP 634 KQ L Y A++ E++ VGT V+++ A D+D NG I +++ + F ID Sbjct: 1419 DSKQVLVPIYYASVPENSQVGTIVTKIHANDSDFAGNGNGVILFDIPHVRGQMQYFSIDN 1478 Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP-----PVFES 689 G++ T LD E+ H+L VA D G+P +ST ++ ++I D+++ P PVF+ Sbjct: 1479 KEGLVTTVGNLDYETQNVHNLTIVASDLGSPSLTSTALLIVRILDVDEGPDEPKRPVFQH 1538 Query: 690 DCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS------ 743 + ENSP+ I ++ D ++ + GD FSL+ + GS Sbjct: 1539 RYYEVEVEENSPVPMRILDLNVSDNNKDEQIRYSIILDEGDGREHFSLDPKNGSLFLLTS 1598 Query: 744 ------DKAELVTMVDLDYES---PRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVM 794 D+ EL VD S P Y +V + + N+ ++ + V DVNDNAP Sbjct: 1599 PDREVRDRYELKVRVDKVKTSRGMPVMIYPVVGKRLNGLGPNEAKIILKVKDVNDNAPRF 1658 Query: 795 K 795 K Sbjct: 1659 K 1659 Score = 142 bits (344), Expect = 1e-31 Identities = 207/856 (24%), Positives = 339/856 (39%), Gaps = 116/856 (13%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ VLD ND+ P FE+ Y S+ E +G +VL + A D+D G N E Y + Sbjct: 597 EVEVLDLNDNLPEFEVDFYNISIVENLPNGFSVLQVIAYDRDQGVNGEFTYELN------ 650 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR--ASLDREKVARYTVLVKATDQASPVS 127 +P A F +D SG L + + LDRE+ + + V A ++ V Sbjct: 651 -DPSGA--------------FSVDPISGWLTVQDQSVLDREQKSFLQMKVLAVEKQPSVV 695 Query: 128 DRL--SSTATIHVNIIDDNDNYPQFSEKTYTVSVDE-DISVTDNPVIAKIKATDADVGAN 184 SS+ + V ++D NDN P F V + D V ++ ++ A D D+G N Sbjct: 696 KPYNGSSSVEVEVTLLDANDNNPVFVPGNLLELVAQSDFKV--GTILGQVHAVDNDLGTN 753 Query: 185 SAIRYAIIG-GNT--QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 +RY + GN +M F+++S +G +++ + E R + A +PS + Sbjct: 754 GLVRYKLQRPGNFTGKMPFAVNSDTGVITVADSPILEG-RHAIFIEAADQPANPSERRFS 812 Query: 242 QLLINI---RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 ++ I R AP F + ++ V NVP+G S+ +++ +A G E+ Y + Sbjct: 813 LAVVTIDVFRPEGSKAPDFIGAPYEFWVGANVPVGTSVGQIRVNEAVNG--NEVVYDLLH 870 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358 + G +P ++ RSG + +++R Q+ Y T+ + S Sbjct: 871 SYHEG---VPFAVEERSGTITVVDEIERYKQSSYDFEAVVTN--EKSLSLVTNVSIHVVD 925 Query: 359 XXXXXXXFMPGQYEVELA---EDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSI 414 F G + L + G + + +A + +H+ I +I Sbjct: 926 PNDESGIFAKGTTKAPLVFHVRENAAGAFIGHVVPANASDSLKNVHFLIANQQDVAEIAI 985 Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPY 474 T G++ L+ ++ + Y LT A G V I + D ++ AP+F + Y Sbjct: 986 TDT---GVLYTPTGLNREKRQNYSLTAIAESPRGVG-VFQVMIIVDDEDDNAPIFSASAY 1041 Query: 475 TASVFEDAPIGTTVLV---VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 + E++ GT V++ VSA D D ++ ++L E S+ F I+ TG Sbjct: 1042 EGRISENSQTGTEVIMTNHVSARDPDE--DSSFMFTLRGEGSD--------LFRIDRNTG 1091 Query: 532 AI----TTNKLLDRETMSGYLLTVTARDGGVPS--------LSDTTDVEISVV------- 572 + +LLDRE Y L + A + S + D D S V Sbjct: 1092 RVFFIGNATELLDREEKPLYNLQIVAGERKKKSSNVSLTIHVDDENDNPPSFVQMVILPD 1151 Query: 573 -------DVNDNEPVFKQQLYTAN---------IMEDALVGTSVSQVGATDADVGLNGRI 616 D D +P Q N + E+ +G + ++ A D D G N I Sbjct: 1152 QGIRVSKDKTDKDPAPTQLTSVTNSDYRSPLLYVPENVTIGIPIIRLVARDPDDGKNAEI 1211 Query: 617 HYEL----------DPKDREEGS----FVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 Y + D K + FV+D SG I AL E+ L+ A D Sbjct: 1212 TYNILSEIGGRTSFDSKTKSSSVVKRYFVMDSRSGEISVAGALPAETDIV--LEIAARDH 1269 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVV 722 G + T+ VH D+ND PVF+ F + E + +G A D D G NA + Sbjct: 1270 GGLMDNVTIRVHAF--DVNDHAPVFKQSWYLFDVPEGNFKRFEMGRFEATDADFGDNANI 1327 Query: 723 HYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEI 782 Y + + NS E + L +D + + + + V +EI Sbjct: 1328 TYELVPTNLDNSVKFEVSRYQGTFSLGGNLDRETRDLYNFKVIAKDGGKIKMSSSVDIEI 1387 Query: 783 LVTDVNDNAPVMKDFQ 798 V DVNDN P FQ Sbjct: 1388 HVQDVNDNPPRFYGFQ 1403 Score = 126 bits (305), Expect = 7e-27 Identities = 191/777 (24%), Positives = 305/777 (39%), Gaps = 118/777 (15%) Query: 71 NPEDAXXXXXXXXXXVQDVFRID-GRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N D+ QDV I +G L T L+REK Y++ A S R Sbjct: 962 NASDSLKNVHFLIANQQDVAEIAITDTGVLYTPTGLNREKRQNYSLTAIAE------SPR 1015 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + + + D++DN P FS Y + E+ S T VI + D +S+ + Sbjct: 1016 GVGVFQVMIIVDDEDDNAPIFSASAYEGRISEN-SQTGTEVIMTNHVSARDPDEDSSFMF 1074 Query: 190 AIIGGNTQMQFSIDSLSGDVSLV----KTLDYEQVRSYR----------------LVIRA 229 + G + + F ID +G V + + LD E+ Y L I Sbjct: 1075 TLRGEGSDL-FRIDRNTGRVFFIGNATELLDREEKPLYNLQIVAGERKKKSSNVSLTIHV 1133 Query: 230 QDGGSPSRSNTTQLLINIRDVN--------DNAPRFYTSLFQES-------VSENVPIGY 274 D S +++ + + D AP TS+ V ENV IG Sbjct: 1134 DDENDNPPSFVQMVILPDQGIRVSKDKTDKDPAPTQLTSVTNSDYRSPLLYVPENVTIGI 1193 Query: 275 SIVRVQAYDADEGVNAELTYTMTDK-----------DYTGNVDLPITIDPRSGWVYTSGQ 323 I+R+ A D D+G NAE+TY + + + V +D RSG + +G Sbjct: 1194 PIIRLVARDPDDGKNAEITYNILSEIGGRTSFDSKTKSSSVVKRYFVMDSRSGEISVAGA 1253 Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383 L ET + + A D G T F Y ++ E Sbjct: 1254 LPAETDIVLE--IAARDHGG--LMDNVTIRVHAFDVNDHAPVFKQSWYLFDVPEGNFKRF 1309 Query: 384 PVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441 + ATDAD ++ + YE+ N +G ++ LD + Y V Sbjct: 1310 EMGRFEATDADFGDNANITYELVPTNLDNSVKFEVSRYQGTFSLGGNLDRETRDLYNFKV 1369 Query: 442 SATDSGG--RSDTAMVQINITDANNYAPVFEN-----------------------AP-YT 475 A D G S + ++I++ D N+ P F P Y Sbjct: 1370 IAKDGGKIKMSSSVDIEIHVQDVNDNPPRFYGFQEMGRLPSNLVDVYRKDSKQVLVPIYY 1429 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 ASV E++ +GT V + A DSD N + +I + V Q F I+ + G +TT Sbjct: 1430 ASVPENSQVGTIVTKIHANDSDFAGNGNGV--ILFDIPH--VRGQMQYFSIDNKEGLVTT 1485 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN-----EPVFKQQLYTANI 590 LD ET + + LT+ A D G PSL+ T + + ++DV++ PVF+ + Y + Sbjct: 1486 VGNLDYETQNVHNLTIVASDLGSPSLTSTALLIVRILDVDEGPDEPKRPVFQHRYYEVEV 1545 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650 E++ V + + +D + R LD D E F +DP +G + + DRE Sbjct: 1546 EENSPVPMRILDLNVSDNNKDEQIRYSIILDEGDGRE-HFSLDPKNGSLFLLTSPDREVR 1604 Query: 651 ATHDLKA----VAIDGGTPPQSSTVI-------------VHIKIEDINDSPPVFESDC-- 691 ++LK V G P V+ + +K++D+ND+ P F+++ Sbjct: 1605 DRYELKVRVDKVKTSRGMPVMIYPVVGKRLNGLGPNEAKIILKVKDVNDNAPRFKTNGRP 1664 Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG--DDSNSFSLETRQGSDKA 746 + + ++ G + ++ A DPDEG N V Y I GG DS F+++ G +A Sbjct: 1665 ILAVLPTSAYYGYNVIKVEAEDPDEGANGQVRYQILGGREQDSPKFAIDPVSGQVQA 1721 Score = 120 bits (290), Expect = 4e-25 Identities = 106/350 (30%), Positives = 168/350 (48%), Gaps = 50/350 (14%) Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN--------EAVAHHDQQFVINPQTG 531 E+ IG ++ + A D D G NA+ITY++ SEI ++ + + FV++ ++G Sbjct: 1187 ENVTIGIPIIRLVARDPDDGKNAEITYNILSEIGGRTSFDSKTKSSSVVKRYFVMDSRSG 1246 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 I+ L ET +L + ARD G L D + + DVND+ PVFKQ Y ++ Sbjct: 1247 EISVAGALPAET--DIVLEIAARDHG--GLMDNVTIRVHAFDVNDHAPVFKQSWYLFDVP 1302 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG-SFVIDPASGVIRTNKALDRESV 650 E + + ATDAD G N I YEL P + + F + G LDRE+ Sbjct: 1303 EGNFKRFEMGRFEATDADFGDNANITYELVPTNLDNSVKFEVSRYQGTFSLGGNLDRETR 1362 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF---------ESDCLTFY------ 695 ++ K +A DGG SS+V + I ++D+ND+PP F S+ + Y Sbjct: 1363 DLYNFKVIAKDGGKIKMSSSVDIEIHVQDVNDNPPRFYGFQEMGRLPSNLVDVYRKDSKQ 1422 Query: 696 ---------ISENSPIGTTIGEIRAHDPD--EGPNAVVHYSIKG-GDDSNSFSLETRQGS 743 + ENS +GT + +I A+D D N V+ + I FS++ ++G Sbjct: 1423 VLVPIYYASVPENSQVGTIVTKIHANDSDFAGNGNGVILFDIPHVRGQMQYFSIDNKEG- 1481 Query: 744 DKAELVTMV-DLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVND 789 LVT V +LDYE+ + + L I A+ SP L + + + + DV++ Sbjct: 1482 ----LVTTVGNLDYET-QNVHNLTIVASDLGSPSLTSTALLIVRILDVDE 1526 Score = 119 bits (287), Expect = 1e-24 Identities = 188/753 (24%), Positives = 311/753 (41%), Gaps = 95/753 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVL-TLKATDQDIGKNAEVEYTIELVTADT 69 I V D +D++P+F YE + E + +GT V+ T + +D +++ +T+ +D Sbjct: 1024 IIVDDEDDNAPIFSASAYEGRISENSQTGTEVIMTNHVSARDPDEDSSFMFTLRGEGSDL 1083 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ----ASP 125 + + + R + L A ++K + ++ + D+ S Sbjct: 1084 FRIDRNTGRVFFIGNATELLDREEKPLYNLQIVAGERKKKSSNVSLTIHVDDENDNPPSF 1143 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED---ISVTDNPVIA----KIKATD 178 V + I V+ D D P ++ T + D + V +N I ++ A D Sbjct: 1144 VQMVILPDQGIRVSK-DKTDKDPAPTQLTSVTNSDYRSPLLYVPENVTIGIPIIRLVARD 1202 Query: 179 ADVGANSAIRYAI---IGGNTQMQ------------FSIDSLSGDVSLVKTLDYEQVRSY 223 D G N+ I Y I IGG T F +DS SG++S+ L E Sbjct: 1203 PDDGKNAEITYNILSEIGGRTSFDSKTKSSSVVKRYFVMDSRSGEISVAGALPAET--DI 1260 Query: 224 RLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYD 283 L I A+D G N T + ++ DVND+AP F S + V E + + R +A D Sbjct: 1261 VLEIAARDHGG-LMDNVT-IRVHAFDVNDHAPVFKQSWYLFDVPEGNFKRFEMGRFEATD 1318 Query: 284 ADEGVNAELTYTM--TDKD---------YTGNVDLPITIDPRSGWVYTSGQLDRE----- 327 AD G NA +TY + T+ D Y G L +D + +Y + ++ Sbjct: 1319 ADFGDNANITYELVPTNLDNSVKFEVSRYQGTFSLGGNLDRETRDLYNFKVIAKDGGKIK 1378 Query: 328 TQAKYQLLVTATDGGD-PPR------SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380 + + + D D PPR +P Y + E+ Sbjct: 1379 MSSSVDIEIHVQDVNDNPPRFYGFQEMGRLPSNLVDVYRKDSKQVLVPIYY-ASVPENSQ 1437 Query: 381 PGTPVVTLTATDADEDNRLHYEITGG--NTRGRFSITS-QNGRGLITVAQPLDFKQERRY 437 GT V + A D+D + I + RG+ S N GL+T LD++ + + Sbjct: 1438 VGTIVTKIHANDSDFAGNGNGVILFDIPHVRGQMQYFSIDNKEGLVTTVGNLDYETQNVH 1497 Query: 438 VLTVSATDSGGRS--DTAMVQINITDANN-----YAPVFENAPYTASVFEDAPIGTTVLV 490 LT+ A+D G S TA++ + I D + PVF++ Y V E++P+ +L Sbjct: 1498 NLTIVASDLGSPSLTSTALLIVRILDVDEGPDEPKRPVFQHRYYEVEVEENSPVPMRILD 1557 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550 ++ +D++ + QI YS+ I +E + F ++P+ G++ DRE Y L Sbjct: 1558 LNVSDNNK--DEQIRYSI---ILDEGDGR--EHFSLDPKNGSLFLLTSPDREVRDRYELK 1610 Query: 551 VTA----RDGGVPSL-------------SDTTDVEISVVDVNDNEPVFKQ--QLYTANIM 591 V G+P + + + + V DVNDN P FK + A + Sbjct: 1611 VRVDKVKTSRGMPVMIYPVVGKRLNGLGPNEAKIILKVKDVNDNAPRFKTNGRPILAVLP 1670 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYE-LDPKDREEGSFVIDPASGVIRT--NKALDRE 648 A G +V +V A D D G NG++ Y+ L ++++ F IDP SG ++ N A D Sbjct: 1671 TSAYYGYNVIKVEAEDPDEGANGQVRYQILGGREQDSPKFAIDPVSGQVQAAGNFARDAG 1730 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681 V D+KA G +SS V + + D N Sbjct: 1731 RVFGFDVKATDRAGAEDGRSSIANVFVYVLDDN 1763 >UniRef50_UPI0000E48BDB Cluster: PREDICTED: similar to FAT tumor suppressor homolog 4, partial; n=3; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to FAT tumor suppressor homolog 4, partial - Strongylocentrotus purpuratus Length = 1282 Score = 202 bits (492), Expect = 1e-49 Identities = 214/810 (26%), Positives = 354/810 (43%), Gaps = 106/810 (13%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+V D N+H+P F E + E + ++V T++A D D+ +A +EY+I +T Sbjct: 547 IDVTDVNEHAPTFAEGVVEVDIEEEVPTDSSVYTVQANDLDV--DAILEYSI----GETA 600 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREK-VARYTVLVKATDQASPVSDR 129 P F ID ++G + T LDR++ Y + V D + Sbjct: 601 GP-----------------FAIDSKTGEISTDGRLDRDEGTTAYNITVVVMDGTN----- 638 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 + + + D NDN P+F+ + +SV E+ TD ++ I+ATD D G N+ I Y Sbjct: 639 -EDDCLVTITLTDINDNAPEFTGGSQALSVSEN--TTDTEMLQVIEATDIDEGVNAEIVY 695 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 + + + FS+D+ +G + DYE V+ Y LVI A D + + T + I D Sbjct: 696 VLESPDDGL-FSVDNETGMLYAHGPFDYEAVKEYTLVISASDSKFLTLTTVT---VTITD 751 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 VNDNAP F + V E+V + I V A D D + Y++ + D+P Sbjct: 752 VNDNAPVFISFCLNIEVLEDVGVDDVICTVGAVDDDGDGEDTVLYSLDPS----SGDVPF 807 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 ++ +G + T G LDRET+ Y + + A D G+PP S+ T F Sbjct: 808 NVNQLTGEIKTDGTLDRETEDIYIITIIAEDSGEPPLSSNTTITVIVLDVNDNIPMFAKT 867 Query: 370 QYEVELAEDEPPGTPVVTLTATDADED----NRLHYEITGGNTRGRFSITSQNGRGLITV 425 V L D+ PV+ D+D N E TGG +T Q+G I Sbjct: 868 SITVRLQTDDLADPPVLLSRVKATDDDLAPWNITQCEKTGGED-SFVVLTGQDGSCEIYA 926 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 + L + V + +A V + + + V FE+ Sbjct: 927 YEELPLSTDPYSVSFYAFNPDNRDRPSANVTLTVDIRDTVCDV---------TFENEADD 977 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 +++ S +++V + +T +++S +++ + TG + ++ M Sbjct: 978 DVIVLKSELETNVPV---VTLNVTSNCNSDDI------------TGEVFPTDIV----ME 1018 Query: 546 G-YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVG 604 G Y+L V A + P +S+TT+V I V N P F++ YT +I ED++ T V +G Sbjct: 1019 GKYILLVRAYNQSDPEVSETTEVTIVVTGEN-TAPAFEEPFYTVDITEDSM--TMVIDLG 1075 Query: 605 --ATDADVG--LNGRIHY----ELDPKDREEGSFVIDPASGVIRTNKA-LDRESVATHDL 655 TD D NG + + E D F + +SG++ T +A L+ T + Sbjct: 1076 PEVTDVDTPSFANGELSFSKVSETDGSGSSTDYFEVS-SSGIVTTTQANLNLIKSGTFQV 1134 Query: 656 KAVAIDGGTPPQSST--VIVHIKIEDIND---SPPVFESDCL-TFYISENSPIGTTIGEI 709 + IDG P S+T VI+++ I+D ++ SPP+ DC T I E + I + Sbjct: 1135 DVMVIDGAIEPLSNTTVVIINVDIDDQSNPVVSPPMITKDCPDTVEIEEETASPVDICRV 1194 Query: 710 RAHDPDEGPNAVVHYSIKGGDDS-NSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768 G +A + G + + F++ T G E+ T +DYE+ + Y L++ Sbjct: 1195 ------SGSSAYDDEVVFGLESALEYFNIGTVSG----EITTTKKIDYETDERSYTLLVY 1244 Query: 769 A--ASPPLWNDVRVEILVTDVNDNAPVMKD 796 A + L N ++VTD+NDNAPV + Sbjct: 1245 AEGTTSKLRNYTSFTVIVTDINDNAPVFSE 1274 Score = 194 bits (472), Expect = 4e-47 Identities = 150/488 (30%), Positives = 232/488 (47%), Gaps = 35/488 (7%) Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI---R 188 S + V ++ D P F++ +Y +V E+ + I +++A ++D+ + + + Sbjct: 434 SVTNVTVRLMPDG-LAPNFTQSSYLGNVSEN--APEGTDIIQVEAINSDMTSEGIVYLLQ 490 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDG-GSPSRSNTTQLLIN 246 A GG FS+D+ SGDVS+V+ LD E+V+ Y L++ A D G+ R + T ++I+ Sbjct: 491 MASDGGEDV--FSVDAESGDVSVVEDGLDAEKVKQYTLIVEAVDERGTYYRYSITSVIID 548 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + DVN++AP F + + + E VP S+ VQA D D V+A L Y++ G Sbjct: 549 VTDVNEHAPTFAEGVVEVDIEEEVPTDSSVYTVQANDLD--VDAILEYSI------GETA 600 Query: 307 LPITIDPRSGWVYTSGQLDR-ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 P ID ++G + T G+LDR E Y + V DG + Sbjct: 601 GPFAIDSKTGEISTDGRLDRDEGTTAYNITVVVMDGTNED---DCLVTITLTDINDNAPE 657 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQNGRGLIT 424 F G + ++E+ + + ATD DE N + G FS+ N G++ Sbjct: 658 FTGGSQALSVSENTTDTEMLQVIEATDIDEGVNAEIVYVLESPDDGLFSV--DNETGMLY 715 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 P D++ + Y L +SA+DS + T V + ITD N+ APVF + V ED + Sbjct: 716 AHGPFDYEAVKEYTLVISASDSKFLTLTT-VTVTITDVNDNAPVFISFCLNIEVLEDVGV 774 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 + V A D D + YSL D F +N TG I T+ LDRET Sbjct: 775 DDVICTVGAVDDDGDGEDTVLYSLDPSSG-------DVPFNVNQLTGEIKTDGTLDRETE 827 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV--SQ 602 Y++T+ A D G P LS T + + V+DVNDN P+F + T + D L V S+ Sbjct: 828 DIYIITIIAEDSGEPPLSSNTTITVIVLDVNDNIPMFAKTSITVRLQTDDLADPPVLLSR 887 Query: 603 VGATDADV 610 V ATD D+ Sbjct: 888 VKATDDDL 895 Score = 193 bits (470), Expect = 7e-47 Identities = 149/494 (30%), Positives = 228/494 (46%), Gaps = 26/494 (5%) Query: 245 INIRDVNDN-APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG 303 + +R + D AP F S + +VSEN P G I++V+A ++D + +E + G Sbjct: 438 VTVRLMPDGLAPNFTQSSYLGNVSENAPEGTDIIQVEAINSD--MTSEGIVYLLQMASDG 495 Query: 304 NVDLPITIDPRSGWV-YTSGQLDRETQAKYQLLVTATDG-GDPPRSATATXXXXXXXXXX 361 D+ ++D SG V LD E +Y L+V A D G R + + Sbjct: 496 GEDV-FSVDAESGDVSVVEDGLDAEKVKQYTLIVEAVDERGTYYRYSITSVIIDVTDVNE 554 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRG 421 F G EV++ E+ P + V T+ A D D D L Y I G T G F+I S+ G Sbjct: 555 HAPTFAEGVVEVDIEEEVPTDSSVYTVQANDLDVDAILEYSI--GETAGPFAIDSKTGE- 611 Query: 422 LITVAQPLDFKQ-ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 I+ LD + Y +TV D G D +V I +TD N+ AP F SV E Sbjct: 612 -ISTDGRLDRDEGTTAYNITVVVMD-GTNEDDCLVTITLTDINDNAPEFTGGSQALSVSE 669 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 + + V+ ATD D G+NA+I Y L S D F ++ +TG + + D Sbjct: 670 NTTDTEMLQVIEATDIDEGVNAEIVYVLESP--------DDGLFSVDNETGMLYAHGPFD 721 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 E + Y L ++A D +L T V +++ DVNDN PVF ++ED V + Sbjct: 722 YEAVKEYTLVISASDSKFLTL---TTVTVTITDVNDNAPVFISFCLNIEVLEDVGVDDVI 778 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 VGA D D + Y LDP + F ++ +G I+T+ LDRE+ + + +A Sbjct: 779 CTVGAVDDDGDGEDTVLYSLDPSSGDV-PFNVNQLTGEIKTDGTLDRETEDIYIITIIAE 837 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN--SPIGTTIGEIRAHDPDEGP 718 D G PP SS + + + D+ND+ P+F +T + + + + ++A D D P Sbjct: 838 DSGEPPLSSNTTITVIVLDVNDNIPMFAKTSITVRLQTDDLADPPVLLSRVKATDDDLAP 897 Query: 719 NAVVHYSIKGGDDS 732 + GG+DS Sbjct: 898 WNITQCEKTGGEDS 911 Score = 182 bits (443), Expect = 1e-43 Identities = 188/746 (25%), Positives = 313/746 (41%), Gaps = 52/746 (6%) Query: 99 LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158 L ++D E Y + A D + T+ V +ID +D P FS+ Y V+ Sbjct: 181 LRLNGTVDFEDQEFYNFTLIAEDGCKSGFNSREGYVTVIVQVIDTDDEPPAFSQDNYDVT 240 Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ----FSIDSLSGDVSLVKT 214 + E S V + A++ D N+ +RY+ I + ID L+ DV++ Sbjct: 241 IPERNSTF---VYTGLSASNGD-SFNTPLRYSFIEQRGEWSCLYYLKIDPLTADVTIRNE 296 Query: 215 LDYEQVRSYRLV-IRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI- 272 LD+E ++ ++A + TT L + + +V + P F + ++E+ P Sbjct: 297 LDFETSPGTCIITVQAVQENDFNMVGTTNLTVTVMNVEE-CPSFILQSYSGQLTEDDPFV 355 Query: 273 ---GYSIVRVQAYDADEGVNAELTYTM-TDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328 G S + ++GV +Y D +++P R + E+ Sbjct: 356 ITDGGSERLIMGMTDEDGVFGGPSYIEPNDTIELVEMNMPEGTMTRFFLIKFLDPASIES 415 Query: 329 QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388 K Q+ ++ D D + T F Y ++E+ P GT ++ + Sbjct: 416 DTKIQIFLS-NDTADM-ECDSVTNVTVRLMPDGLAPNFTQSSYLGNVSENAPEGTDIIQV 473 Query: 389 TATDADEDNR-LHYEITGGNTRGR--FSITSQNGRGLITVAQPLDFKQERRYVLTVSATD 445 A ++D + + Y + + G FS+ +++G + V LD ++ ++Y L V A D Sbjct: 474 EAINSDMTSEGIVYLLQMASDGGEDVFSVDAESG-DVSVVEDGLDAEKVKQYTLIVEAVD 532 Query: 446 SGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502 G R V I++TD N +AP F + E+ P ++V V A D DV +A Sbjct: 533 ERGTYYRYSITSVIIDVTDVNEHAPTFAEGVVEVDIEEEVPTDSSVYTVQANDLDV--DA 590 Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR-ETMSGYLLTVTARDGGVPSL 561 + YS+ F I+ +TG I+T+ LDR E + Y +TV DG + Sbjct: 591 ILEYSIGETAG---------PFAIDSKTGEISTDGRLDRDEGTTAYNITVVVMDG---TN 638 Query: 562 SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621 D V I++ D+NDN P F ++ E+ + + ATD D G+N I Y L+ Sbjct: 639 EDDCLVTITLTDINDNAPEFTGGSQALSVSENTTDTEMLQVIEATDIDEGVNAEIVYVLE 698 Query: 622 PKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIN 681 D +G F +D +G++ + D E+V + L A D + V + I D+N Sbjct: 699 SPD--DGLFSVDNETGMLYAHGPFDYEAVKEYTLVISASDSKF---LTLTTVTVTITDVN 753 Query: 682 DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQ 741 D+ PVF S CL + E+ + I + A D D V YS+ F++ Sbjct: 754 DNAPVFISFCLNIEVLEDVGVDDVICTVGAVDDDGDGEDTVLYSLDPSSGDVPFNVNQLT 813 Query: 742 GSDKAELVTMVDLDYESPRKKYELVIR--AASPPLWNDVRVEILVTDVNDNAPVMKDFQI 799 G E+ T LD E+ +I + PPL ++ + ++V DVNDN P+ I Sbjct: 814 G----EIKTDGTLDRETEDIYIITIIAEDSGEPPLSSNTTITVIVLDVNDNIPMFAKTSI 869 Query: 800 IFNNYKDCFPVGP--FGRVPAYDADV 823 D P RV A D D+ Sbjct: 870 TVRLQTDDLADPPVLLSRVKATDDDL 895 >UniRef50_Q9P2E7 Cluster: Protocadherin-10 precursor; n=34; Euteleostomi|Rep: Protocadherin-10 precursor - Homo sapiens (Human) Length = 1040 Score = 202 bits (492), Expect = 1e-49 Identities = 182/625 (29%), Positives = 270/625 (43%), Gaps = 55/625 (8%) Query: 96 SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155 +G L +DRE++ + + + + + ++D NDN P F E Sbjct: 70 TGVLYVNEKIDREQICKQSP--SCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEPDL 127 Query: 156 TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSID-SLSGD------ 208 TV + E S T A D DVG NS Y I + FS+D GD Sbjct: 128 TVEISE--SATPGTRFPLESAFDPDVGTNSLRDYEITPNS---YFSLDVQTQGDGNRFAE 182 Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGS-------------------PSRSNTTQLLINIRD 249 + L K LD EQ +R V+ A DGG R+ T L I + D Sbjct: 183 LVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLD 242 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 NDN P F ++ S+ EN P G ++++ A D DEG N E+ Y+ + +L Sbjct: 243 SNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRAREL-F 301 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 + PR+G + SG+LD E YQ+ V A D G A Sbjct: 302 GLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFS 361 Query: 370 QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 + ++E PGT V + TD D E+ ++ E+ G+ R + +N ++T A Sbjct: 362 TVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELL-GDVPFRLKSSFKNYYTIVTEA- 419 Query: 428 PLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 PLD + Y LTV A D G S + +Q+ ++D N+ AP F Y V E+ G Sbjct: 420 PLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPG 479 Query: 486 TTVLVVSATDSDVGINAQITYS-LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 + VSATD D G NAQ+ YS L +I +V + IN + G + + D E + Sbjct: 480 AYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTY---VSINSENGYLYALRSFDYEQL 536 Query: 545 SGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTAN-------IMEDALV 596 + V ARD G P +L+ V I +VD NDN P L N + A Sbjct: 537 KDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEP 596 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL--DRESVATHD 654 G +++V A DAD G N R+ Y + + E F +D +G +RT + + R+ ++ Sbjct: 597 GYLLTRVAAVDADDGENARLTYSI-VRGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYE 655 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIED 679 L D G PP SST + +++ D Sbjct: 656 LVIEVRDHGQPPLSSTATLVVQLVD 680 Score = 191 bits (465), Expect = 3e-46 Identities = 167/587 (28%), Positives = 255/587 (43%), Gaps = 55/587 (9%) Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 Q+ I + D+NDN P F +SE+ G A+D D G N+ Y +T Y Sbjct: 107 QVEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSY 166 Query: 302 TGNVDLPITIDP-RSGWVYTSGQLDRETQAKYQLLVTATDGGD----------------P 344 ++D+ D R + LDRE QA ++ ++TA DGG P Sbjct: 167 F-SLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLP 225 Query: 345 P---RSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRL 399 P R+ TA F Y V L E+ PPGT V+ L ATD DE + + Sbjct: 226 PQQQRTGTALLTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEV 285 Query: 400 HYEITGG---NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA--M 454 Y + R F ++ + GR + V+ LD+++ Y + V A D G + A Sbjct: 286 VYSFSSHISPRARELFGLSPRTGR--LEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCK 343 Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 V + + DAN+ AP + +V E A GT V + S TD D N Q+ L ++ Sbjct: 344 VLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPF 403 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 + + I T LDRE Y LTV ARD G P+LS + +++ V DV Sbjct: 404 RLKSSFKNYYTI-------VTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDV 456 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY---ELDPKDREEGSFV 631 NDN P F Q +Y + E+ + G + V ATD D G N ++ Y E + ++V Sbjct: 457 NDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYV 516 Query: 632 -IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPVFES 689 I+ +G + ++ D E + + A D G+P + V+I I D ND+ P + Sbjct: 517 SINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVA 576 Query: 690 DC-------LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 + ++ G + + A D D+G NA + YSI G++ N F ++ R G Sbjct: 577 PLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTG 636 Query: 743 SDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTD 786 + D P++ YELVI PPL + + + + D Sbjct: 637 ELRTARRVPAKRD---PQRPYELVIEVRDHGQPPLSSTATLVVQLVD 680 Score = 181 bits (440), Expect = 3e-43 Identities = 162/518 (31%), Positives = 236/518 (45%), Gaps = 49/518 (9%) Query: 373 VELAEDEPPGTPVVTLTATDADED-NRLH-YEITGGNTRGRFSITSQNGRGL--ITVAQP 428 VE++E PGT +A D D N L YEIT + T +G + + +P Sbjct: 129 VEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFSLDVQTQGDGNRFAELVLEKP 188 Query: 429 LDFKQE--RRYVLTVSATDSGG-------------------RSDTAMVQINITDANNYAP 467 LD +Q+ RYVLT GG R+ TA++ I + D+N+ P Sbjct: 189 LDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVP 248 Query: 468 VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527 F+ YT S+ E++P GT V+ ++ATD D G N ++ YS SS IS A + F ++ Sbjct: 249 AFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRA----RELFGLS 304 Query: 528 PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT 587 P+TG + + LD E Y + V A+D G ++ V + V+D NDN P Sbjct: 305 PRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVK 364 Query: 588 ANIMEDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKAL 645 + E A GT V+ TD D NG++ EL D R + SF I T L Sbjct: 365 EAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDVPFRLKSSF---KNYYTIVTEAPL 421 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 DRE+ ++ L VA D G P S++ + +++ D+ND+ P F Y++EN+ G Sbjct: 422 DREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAY 481 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGD-DSNSFSLETRQGSDKAELVTMVDLDYESPRK-KY 763 I + A D DEG NA + YSI S S+ L + DYE + + Sbjct: 482 IYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSF 541 Query: 764 ELVIRAASPP--LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP--------F 813 ++ R A P L + V IL+ D NDNAP + + N V P Sbjct: 542 QVEARDAGSPQALAGNATVNILIVDQNDNAPAIV-APLPGRNGTPAREVLPRSAEPGYLL 600 Query: 814 GRVPAYDADVTD--KLQYRILSGNNANLILLNETTGSM 849 RV A DAD + +L Y I+ GN NL ++ TG + Sbjct: 601 TRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGEL 638 Score = 167 bits (406), Expect = 4e-39 Identities = 158/602 (26%), Positives = 257/602 (42%), Gaps = 68/602 (11%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I VLD ND+ P F + E A+ GT A D D+G N+ +Y I + + Sbjct: 109 EIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPNSYFS 168 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQAS---- 124 L+ + DG R L+ LDRE+ A + ++ A D Sbjct: 169 LDVQTQG----------------DGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGV 212 Query: 125 ------------PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIA 172 P + + TA + + ++D NDN P F + YTVS+ E + ++ Sbjct: 213 GEGGGGGGGAGLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVYTVSLPE--NSPPGTLVI 270 Query: 173 KIKATDADVGANSAIRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA 229 ++ ATD D G N + Y+ I + F + +G + + LDYE+ Y++ ++A Sbjct: 271 QLNATDPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQA 330 Query: 230 QDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN 289 +D G + ++L+ + D NDNAP S +E+VSE G + D D N Sbjct: 331 KDLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEEN 390 Query: 290 AELTYTMTDKDYTGNVDLPITIDPRSGW-VYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348 ++ + G+V + ++ + + T LDRE Y L V A D G+P S Sbjct: 391 GQV-----QCELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALST 445 Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGG 406 + + F Y+V + E+ PG + ++ATD DE + +L Y I Sbjct: 446 SKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILEC 505 Query: 407 NTRGR--FSITSQNG-RGLITVAQPLDFKQERRYVLTVSATDSG---GRSDTAMVQINIT 460 +G F+ S N G + + D++Q + + V A D+G + A V I I Sbjct: 506 QIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIV 565 Query: 461 DANNYAPVF-------ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513 D N+ AP P + A G + V+A D+D G NA++TYS+ Sbjct: 566 DQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVR--G 623 Query: 514 NEAVAHHDQQFVINPQTGAITTNKLL--DRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571 NE F ++ +TG + T + + R+ Y L + RD G P LS T + + + Sbjct: 624 NEM-----NLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQL 678 Query: 572 VD 573 VD Sbjct: 679 VD 680 Score = 148 bits (358), Expect = 3e-33 Identities = 116/365 (31%), Positives = 180/365 (49%), Gaps = 43/365 (11%) Query: 2 SVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 +VP + VLD ND++P + +V EGA+ GT V TD+D +N +V+ Sbjct: 337 AVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQ-- 394 Query: 62 IELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121 EL+ ++ F+ ++T A LDRE YT+ V A D Sbjct: 395 CELL--------------GDVPFRLKSSFK---NYYTIVTEAPLDREAGDSYTLTVVARD 437 Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181 + P LS++ +I V + D NDN P+FS+ Y V V E + I + ATD D Sbjct: 438 RGEPA---LSTSKSIQVQVSDVNDNAPRFSQPVYDVYVTE--NNVPGAYIYAVSATDRDE 492 Query: 182 GANSAIRYAII-----GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP- 235 GAN+ + Y+I+ G + SI+S +G + +++ DYEQ++ + + A+D GSP Sbjct: 493 GANAQLAYSILECQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQ 552 Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSL-------FQESVSENVPIGYSIVRVQAYDADEGV 288 + + + I I D NDNAP L +E + + GY + RV A DAD+G Sbjct: 553 ALAGNATVNILIVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGE 612 Query: 289 NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL--DRETQAKYQLLVTATDGGDPPR 346 NA LTY++ GN +D R+G + T+ ++ R+ Q Y+L++ D G PP Sbjct: 613 NARLTYSIV----RGNEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPL 668 Query: 347 SATAT 351 S+TAT Sbjct: 669 SSTAT 673 Score = 103 bits (247), Expect = 7e-20 Identities = 93/299 (31%), Positives = 131/299 (43%), Gaps = 40/299 (13%) Query: 526 INPQTGAITTNKLLDRETMSGYLLT-VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584 +N +TG + N+ +DRE + + V + + + + VEI V+D+NDN P F + Sbjct: 66 LNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEP 125 Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS-------G 637 T I E A GT A D DVG N YE+ P F +D + Sbjct: 126 DLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITP----NSYFSLDVQTQGDGNRFA 181 Query: 638 VIRTNKALDRESVATHDLKAVAIDG----------------GTPPQ---SSTVIVHIKIE 678 + K LDRE A H A+DG G PPQ + T ++ I++ Sbjct: 182 ELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPPQQQRTGTALLTIRVL 241 Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS---F 735 D ND+ P F+ T + ENSP GT + ++ A DPDEG N V YS + F Sbjct: 242 DSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVVYSFSSHISPRARELF 301 Query: 736 SLETRQGSDKAELVTMVDLDY-ESPRKKYELVIRAASP-PLWNDVRVEILVTDVNDNAP 792 L R G L +LDY ESP + + + P + +V + V D NDNAP Sbjct: 302 GLSPRTG----RLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLVRVLDANDNAP 356 Score = 57.2 bits (132), Expect = 6e-06 Identities = 55/185 (29%), Positives = 82/185 (44%), Gaps = 11/185 (5%) Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGAT-DADVGLNGRIHYELDPKDREEGSFVIDPAS 636 E VF Q YT + E+ GT V + D+ ++ P R ++ + Sbjct: 14 EGVFSQLHYT--VQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRTP-YLDLNLET 70 Query: 637 GVIRTNKALDRESVATHDLKAVA-IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695 GV+ N+ +DRE + V ++ V I++ DIND+PP F LT Sbjct: 71 GVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEVLDINDNPPSFPEPDLTVE 130 Query: 696 ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR---QGSDKAELVTMV 752 ISE++ GT A DPD G N++ Y I ++ FSL+ + G+ AELV Sbjct: 131 ISESATPGTRFPLESAFDPDVGTNSLRDYEI---TPNSYFSLDVQTQGDGNRFAELVLEK 187 Query: 753 DLDYE 757 LD E Sbjct: 188 PLDRE 192 >UniRef50_Q9HBT6 Cluster: Cadherin-20 precursor; n=261; Euteleostomi|Rep: Cadherin-20 precursor - Homo sapiens (Human) Length = 801 Score = 201 bits (490), Expect = 3e-49 Identities = 164/549 (29%), Positives = 263/549 (47%), Gaps = 46/549 (8%) Query: 161 EDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV 220 E+ + TD + K+ + D D G S I+Y + G + F+ID +GD+ ++ LD E+ Sbjct: 70 EEYTGTDPLYVGKLHS-DMDRGDGS-IKYILSGEGAGIVFTIDDTTGDIHAIQRLDREER 127 Query: 221 RSYRLVIRAQD--GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR 278 Y L +A D G P ++ +I I+D+NDN P+F + +V E P+G S+++ Sbjct: 128 AQYTLRAQALDRRTGRPMEPE-SEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQ 186 Query: 279 VQAYDADE---GVNAELTYT-MTDKDYTGNVDLPITIDPRSGWVYTS-GQLDRETQAKYQ 333 V A DAD+ G +A + Y+ + + Y ++D ++G + T+ +DRE + Y+ Sbjct: 187 VTATDADDPTYGNSARVVYSILQGQPY-------FSVDSKTGVIRTALMNMDREAKEYYE 239 Query: 334 LLVTATD-GGD-PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTAT 391 +++ A D GG + T T F Y++ + E P + V + A Sbjct: 240 VIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAK 299 Query: 392 DADE--DNRLHYEITGGNTRGRFSI-TSQNGR-GLITVAQPLDFKQERRYVLTVSATDS- 446 D DE + + Y I G+ F I T N + G+ITV +PL F+ ++ Y L V + Sbjct: 300 DLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPH 359 Query: 447 --------GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498 G DT V I++ D + PVFE Y V ED IGTT+ ++SA D DV Sbjct: 360 LEMRFLNLGPFQDTTTVHISVEDVDE-PPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDV 418 Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558 N I YS+ + + + F ++ TGA+ T + LDRE S + +TV A + Sbjct: 419 -TNNSIRYSI------DRSSDPGRFFYVDITTGALMTARPLDREEFSWHNITVLAMEMNN 471 Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR-IH 617 PS + V I V+DVNDN P F + Y A + E+A G + V A D D NG+ + Sbjct: 472 PSQVGSVPVTIKVLDVNDNAPEF-PRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFY 530 Query: 618 YELDPKDREEGSFVI----DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673 Y L P+ +F I D + ++ ++ + L + D G P SST + Sbjct: 531 YSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTL 590 Query: 674 HIKIEDIND 682 I++ +D Sbjct: 591 TIQVCSCDD 599 Score = 188 bits (457), Expect = 3e-45 Identities = 152/506 (30%), Positives = 226/506 (44%), Gaps = 30/506 (5%) Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP-PRSATATXXXXXXXXXXXXXXFMP 368 TID +G ++ +LDRE +A+Y L A D P + F+ Sbjct: 108 TIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKFLD 167 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDN-----RLHYEITGGNTRGRFSITSQNGRGLI 423 G Y + E P GT V+ +TATDAD+ R+ Y I G FS+ S+ G + Sbjct: 168 GPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQPY--FSVDSKTGV-IR 224 Query: 424 TVAQPLDFKQERRYVLTVSATDSGGR----SDTAMVQINITDANNYAPVFENAPYTASVF 479 T +D + + Y + + A D GG+ + T V I ++D N+ P F Y SV Sbjct: 225 TALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVL 284 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E API +TV V A D D GINA++ Y++ + + D N Q G IT K L Sbjct: 285 ESAPISSTVGRVFAKDLDEGINAEMKYTI---VDGDGADAFDISTDPNFQVGIITVKKPL 341 Query: 540 DRETMSGYLLTVTARDG-------GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592 E+ Y L V + + DTT V ISV DV D PVF+ Y + E Sbjct: 342 SFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDV-DEPPVFEPGFYFVEVPE 400 Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652 D +GT++ + A D DV N I Y +D F +D +G + T + LDRE + Sbjct: 401 DVAIGTTIQIISAKDPDV-TNNSIRYSIDRSSDPGRFFYVDITTGALMTARPLDREEFSW 459 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 H++ +A++ P Q +V V IK+ D+ND+ P F F + EN+ G I + A Sbjct: 460 HNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRFYEAF-VCENAKAGQLIQTVSAV 518 Query: 713 DPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK-AELVTMVDLDYESPRKKYELVIRAA- 770 D D+ N Y + +N+ + R D A ++T + + + L I A Sbjct: 519 DQDDPRNGQHFYYSLAPEAANNPNFTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIAD 578 Query: 771 --SPPLWNDVRVEILVTDVNDNAPVM 794 P L + + I V +D+ VM Sbjct: 579 SGQPVLSSTGTLTIQVCSCDDDGHVM 604 Score = 184 bits (449), Expect = 2e-44 Identities = 159/507 (31%), Positives = 237/507 (46%), Gaps = 30/507 (5%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 VF ID +G + LDRE+ A+YT+ +A D+ + + + + I D NDN P Sbjct: 106 VFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRT--GRPMEPESEFIIKIQDINDNEP 163 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDAD---VGANSAIRYAIIGGNTQMQFSIDSL 205 +F + Y +V E +S VI ++ ATDAD G ++ + Y+I+ G Q FS+DS Sbjct: 164 KFLDGPYVATVPE-MSPVGTSVI-QVTATDADDPTYGNSARVVYSILQG--QPYFSVDSK 219 Query: 206 SGDV-SLVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQLLINIRDVNDNAPRFYTSLF 262 +G + + + +D E Y ++I+A+D G + TT + I + DVNDN PRF + Sbjct: 220 TGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHY 279 Query: 263 QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322 Q SV E+ PI ++ RV A D DEG+NAE+ YT+ D D D+ + + G + Sbjct: 280 QMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKK 339 Query: 323 QLDRETQAKYQLLVTATDGGDPPRSAT------ATXXXXXXXXXXXXXXFMPGQYEVELA 376 L E++ Y L V + R T F PG Y VE+ Sbjct: 340 PLSFESKKSYTLKVEGANPHLEMRFLNLGPFQDTTTVHISVEDVDEPPVFEPGFYFVEVP 399 Query: 377 EDEPPGTPVVTLTATDAD-EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435 ED GT + ++A D D +N + Y I + GRF L+T A+PLD ++ Sbjct: 400 EDVAIGTTIQIISAKDPDVTNNSIRYSIDRSSDPGRFFYVDITTGALMT-ARPLDREEFS 458 Query: 436 RYVLTVSATDSGGRSD--TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 + +TV A + S + V I + D N+ AP F Y A V E+A G + VSA Sbjct: 459 WHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEFPRF-YEAFVCENAKAGQLIQTVSA 517 Query: 494 TDSDVGINAQ-ITYSLSSEISNEA-VAHHDQQFVINPQTGAITTNKL-LDRETMSGYLLT 550 D D N Q YSL+ E +N D Q T I T + ++ S + L Sbjct: 518 VDQDDPRNGQHFYYSLAPEAANNPNFTIRDNQ----DNTARILTRRSGFRQQEQSVFHLP 573 Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDN 577 + D G P LS T + I V +D+ Sbjct: 574 ILIADSGQPVLSSTGTLTIQVCSCDDD 600 Score = 164 bits (399), Expect = 3e-38 Identities = 142/434 (32%), Positives = 207/434 (47%), Gaps = 40/434 (9%) Query: 391 TDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG-G 448 +D D D + Y ++G F+I G I Q LD ++ +Y L A D G Sbjct: 85 SDMDRGDGSIKYILSGEGAGIVFTIDDTTGD--IHAIQRLDREERAQYTLRAQALDRRTG 142 Query: 449 R--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506 R + I I D N+ P F + PY A+V E +P+GT+V+ V+ATD+D TY Sbjct: 143 RPMEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDAD-----DPTY 197 Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAITTNKL-LDRETMSGYLLTVTARD--GGVPSLSD 563 S+ + ++ F ++ +TG I T + +DRE Y + + A+D G + L+ Sbjct: 198 GNSARVVY-SILQGQPYFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAG 256 Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK 623 TT V I++ DVNDN P F Q+ Y +++E A + ++V +V A D D G+N + Y + Sbjct: 257 TTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLDEGINAEMKYTIVDG 316 Query: 624 DREEGSFV-IDP--ASGVIRTNKALDRESVATHDLKAVAIDGGTP----------PQSST 670 D + + DP G+I K L ES ++ LK ++G P P T Sbjct: 317 DGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLK---VEGANPHLEMRFLNLGPFQDT 373 Query: 671 VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-KGG 729 VHI +ED+ D PPVFE + E+ IGTTI I A DPD N++ YSI + Sbjct: 374 TTVHISVEDV-DEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTNNSI-RYSIDRSS 431 Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYE--SPRKKYELVIRAASPPLWNDVRVEILVTDV 787 D F ++ G+ L+T LD E S L + +P V V I V DV Sbjct: 432 DPGRFFYVDITTGA----LMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIKVLDV 487 Query: 788 NDNAPVMKDFQIIF 801 NDNAP F F Sbjct: 488 NDNAPEFPRFYEAF 501 Score = 133 bits (321), Expect = 8e-29 Identities = 123/391 (31%), Positives = 183/391 (46%), Gaps = 35/391 (8%) Query: 485 GTTVLVVSATDSDVGI-NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 GT L V SD+ + I Y LS E + F I+ TG I + LDRE Sbjct: 74 GTDPLYVGKLHSDMDRGDGSIKYILSGEGAGIV-------FTIDDTTGDIHAIQRLDREE 126 Query: 544 MSGYLLTVTARDG--GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 + Y L A D G P + ++ I + D+NDNEP F Y A + E + VGTSV Sbjct: 127 RAQYTLRAQALDRRTGRP-MEPESEFIIKIQDINDNEPKFLDGPYVATVPEMSPVGTSVI 185 Query: 602 QVGATDAD---VGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA-LDRESVATHD--L 655 QV ATDAD G + R+ Y + + + F +D +GVIRT +DRE+ ++ + Sbjct: 186 QVTATDADDPTYGNSARVVYSIL---QGQPYFSVDSKTGVIRTALMNMDREAKEYYEVII 242 Query: 656 KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 +A + G + T V+I + D+ND+PP F + E++PI +T+G + A D D Sbjct: 243 QAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISSTVGRVFAKDLD 302 Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP--- 772 EG NA + Y+I GD +++F + T + L +ES +K Y L + A+P Sbjct: 303 EGINAEMKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFES-KKSYTLKVEGANPHLE 361 Query: 773 -------PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVT- 824 P + V I V DV D PV + +D + A D DVT Sbjct: 362 MRFLNLGPFQDTTTVHISVEDV-DEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDVTN 420 Query: 825 DKLQYRI-LSGNNANLILLNETTGS-MTLSP 853 + ++Y I S + ++ TTG+ MT P Sbjct: 421 NSIRYSIDRSSDPGRFFYVDITTGALMTARP 451 Score = 120 bits (290), Expect = 4e-25 Identities = 122/486 (25%), Positives = 209/486 (43%), Gaps = 53/486 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVTA 67 I + D ND+ P F Y A+V E + GT+V+ + ATD D G +A V Y+I Sbjct: 153 IKIQDINDNEPKFLDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSI----- 207 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR-ASLDREKVARYTVLVKATDQASPV 126 Q F +D ++G + T ++DRE Y V+++A D + Sbjct: 208 ----------------LQGQPYFSVDSKTGVIRTALMNMDREAKEYYEVIIQAKDMGGQL 251 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 L+ T T+++ + D NDN P+F +K Y +SV E ++ + ++ A D D G N+ Sbjct: 252 GG-LAGTTTVNITLSDVNDNPPRFPQKHYQMSVLESAPISS--TVGRVFAKDLDEGINAE 308 Query: 187 IRYAIIGGNTQMQFSIDS----LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR----- 237 ++Y I+ G+ F I + G +++ K L +E +SY L + + R Sbjct: 309 MKYTIVDGDGADAFDISTDPNFQVGIITVKKPLSFESKKSYTLKVEGANPHLEMRFLNLG 368 Query: 238 --SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295 +TT + I++ DV D P F + V E+V IG +I + A D D N + Y+ Sbjct: 369 PFQDTTTVHISVEDV-DEPPVFEPGFYFVEVPEDVAIGTTIQIISAKDPDV-TNNSIRYS 426 Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355 + G +D +G + T+ LDRE + + + V A + +P + + Sbjct: 427 IDRSSDPGRF---FYVDITTGALMTARPLDREEFSWHNITVLAMEMNNPSQVGSVPVTIK 483 Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEIT---GGNTRGR 411 F P YE + E+ G + T++A D D+ N H+ + Sbjct: 484 VLDVNDNAPEF-PRFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYYSLAPEAANNPN 542 Query: 412 FSITSQNGRGLITVAQPLDFKQERRYV--LTVSATDSGG--RSDTAMVQINITDANNYAP 467 F+I + + F+Q+ + V L + DSG S T + I + ++ Sbjct: 543 FTIRDNQDNTARILTRRSGFRQQEQSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGH 602 Query: 468 VFENAP 473 V +P Sbjct: 603 VMSCSP 608 Score = 46.0 bits (104), Expect = 0.015 Identities = 47/164 (28%), Positives = 75/164 (45%), Gaps = 23/164 (14%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I VLD ND++P F + YEA V E A +G + T+ A DQD +N + Y +L Sbjct: 482 IKVLDVNDNAPEFP-RFYEAFVCENAKAGQLIQTVSAVDQDDPRNGQHFYY-------SL 533 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 PE A + RI L R+ +++ + + + + D PV L Sbjct: 534 APEAANNPNFTIRDNQDNTARI------LTRRSGFRQQEQSVFHLPILIADSGQPV---L 584 Query: 131 SSTATIHVNI--IDDNDNYPQFSEKTYTVSVDEDISVTDNPVIA 172 SST T+ + + DD+ + S + Y + V S++ P+IA Sbjct: 585 SSTGTLTIQVCSCDDDGHVMSCSPEAYMLPV----SLSRGPLIA 624 >UniRef50_Q6R0I8 Cluster: Cadherin-related neuronal receptor 3; n=23; Gallus gallus|Rep: Cadherin-related neuronal receptor 3 - Gallus gallus (Chicken) Length = 1000 Score = 200 bits (487), Expect = 6e-49 Identities = 143/445 (32%), Positives = 216/445 (48%), Gaps = 23/445 (5%) Query: 368 PGQYE-VELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGR-FSITSQNGRGLI 423 P Y+ + +AE PG+ A+DAD + +L Y ++ N + L Sbjct: 132 PAAYKNISIAESSLPGSRFPLEGASDADIGSNAQLSYSLSPSEHFALDVKSPDDNLKSLF 191 Query: 424 TV-AQPLDFKQERRYVLTVSATDSGGRSDTAMVQ--INITDANNYAPVFENAPYTASVFE 480 V PLD + + L ++A+D G + T VQ I++ DAN+ AP F + Y + E Sbjct: 192 LVLTHPLDRESLSEHRLVLTASDGGRPALTGTVQLVISVLDANDNAPQFNQSVYKVQLPE 251 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 DA GT V V+ATD DVG N + +YS+ S + A F I+P+TG I LD Sbjct: 252 DAAEGTLVARVAATDPDVGFNQEFSYSIVSSVP----ASQSDAFSIDPRTGEIRLTGPLD 307 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 E + + L + ARD G P LS V + V+DVNDN P + + EDA +GT V Sbjct: 308 FEDVHQHELQIEARDKGTPPLSGHCSVILEVLDVNDNAPEVWVTSLSVPVPEDAALGTVV 367 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 + + +D D G NGR+ + P G S + +ALDRE V+ ++++ A Sbjct: 368 ALLSVSDRDSGPNGRVRCAVRPPS-PFGLVATFAGSYSLVLREALDRERVSEYEVEVRAE 426 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 DGG PP ++ + + + D+ND+ P F T EN+ G + + A DPDE N Sbjct: 427 DGGAPPLRASRGLRVPVSDVNDNAPAFAQAVYTVLARENNAAGAELARLWARDPDEAGNG 486 Query: 721 VVHYSI-KGGDDSNS--------FSLETRQGSDKAELVTMVDLDYESPR-KKYEL-VIRA 769 V YS+ +GG + S S ++ L + LDYE + ++E+ + A Sbjct: 487 RVSYSVAEGGAGTGSGSGSGWRPASSYVSVDAESGRLRALRPLDYEELQVLQFEVRAVDA 546 Query: 770 ASPPLWNDVRVEILVTDVNDNAPVM 794 PPL + V++ V D NDNAP + Sbjct: 547 GEPPLCGNATVQLFVVDENDNAPAL 571 Score = 189 bits (460), Expect = 1e-45 Identities = 125/344 (36%), Positives = 184/344 (53%), Gaps = 15/344 (4%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 V++ +TD N+ AP F A S+ E + G+ + A+D+D+G NAQ++YSLS + Sbjct: 117 VEVEVTDINDNAPRFPAAYKNISIAESSLPGSRFPLEGASDADIGSNAQLSYSLSP---S 173 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 E A + N ++ + LDRE++S + L +TA DGG P+L+ T + ISV+D Sbjct: 174 EHFALDVKSPDDNLKSLFLVLTHPLDRESLSEHRLVLTASDGGRPALTGTVQLVISVLDA 233 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL--DPKDREEGSFVI 632 NDN P F Q +Y + EDA GT V++V ATD DVG N Y + + +F I Sbjct: 234 NDNAPQFNQSVYKVQLPEDAAEGTLVARVAATDPDVGFNQEFSYSIVSSVPASQSDAFSI 293 Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692 DP +G IR LD E V H+L+ A D GTPP S V +++ D+ND+ P L Sbjct: 294 DPRTGEIRLTGPLDFEDVHQHELQIEARDKGTPPLSGHCSVILEVLDVNDNAPEVWVTSL 353 Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSL-ETRQGSDKAELVTM 751 + + E++ +GT + + D D GPN V +++ + F L T GS LV Sbjct: 354 SVPVPEDAALGTVVALLSVSDRDSGPNGRVRCAVR---PPSPFGLVATFAGS--YSLVLR 408 Query: 752 VDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792 LD E +YE+ +RA +PPL + + V+DVNDNAP Sbjct: 409 EALDRERV-SEYEVEVRAEDGGAPPLRASRGLRVPVSDVNDNAP 451 Score = 186 bits (454), Expect = 6e-45 Identities = 147/527 (27%), Positives = 239/527 (45%), Gaps = 31/527 (5%) Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV--RSYRLVIRAQDG-GSPS 236 + G A R ++ + + SG + + LD E++ +S +R + P Sbjct: 53 EAGEAEARRLRLVARGRRASVEVSGASGALVVSSRLDREELCGKSAPCALRLEVLLDRPL 112 Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 R + + + D+NDNAPRF + S++E+ G A DAD G NA+L+Y++ Sbjct: 113 R--VFHVEVEVTDINDNAPRFPAAYKNISIAESSLPGSRFPLEGASDADIGSNAQLSYSL 170 Query: 297 TDKDYTGNVDLPITIDP-RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355 + ++ +D+ D +S ++ + LDRE+ ++++L++TA+DGG P + T Sbjct: 171 SPSEHFA-LDVKSPDDNLKSLFLVLTHPLDRESLSEHRLVLTASDGGRPALTGTVQLVIS 229 Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFS 413 F Y+V+L ED GT V + ATD D + Y I + Sbjct: 230 VLDANDNAPQFNQSVYKVQLPEDAAEGTLVARVAATDPDVGFNQEFSYSIVSSVPASQSD 289 Query: 414 ITSQNGR-GLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFE 470 S + R G I + PLDF+ ++ L + A D G S V + + D N+ AP Sbjct: 290 AFSIDPRTGEIRLTGPLDFEDVHQHELQIEARDKGTPPLSGHCSVILEVLDVNDNAPEVW 349 Query: 471 NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 + V EDA +GT V ++S +D D G N ++ ++ VA + Sbjct: 350 VTSLSVPVPEDAALGTVVALLSVSDRDSGPNGRVRCAVRPPSPFGLVATFAGSY------ 403 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590 ++ + LDRE +S Y + V A DGG P L + + + V DVNDN P F Q +YT Sbjct: 404 -SLVLREALDRERVSEYEVEVRAEDGGAPPLRASRGLRVPVSDVNDNAPAFAQAVYTVLA 462 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKD-----------REEGSFV-IDPASGV 638 E+ G ++++ A D D NGR+ Y + R S+V +D SG Sbjct: 463 RENNAAGAELARLWARDPDEAGNGRVSYSVAEGGAGTGSGSGSGWRPASSYVSVDAESGR 522 Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685 +R + LD E + + A+D G PP V + + D ND+ P Sbjct: 523 LRALRPLDYEELQVLQFEVRAVDAGEPPLCGNATVQLFVVDENDNAP 569 Score = 182 bits (442), Expect = 2e-43 Identities = 139/505 (27%), Positives = 228/505 (45%), Gaps = 27/505 (5%) Query: 92 IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151 + G SGAL+ + LDRE++ + + + DR + V + D NDN P+F Sbjct: 75 VSGASGALVVSSRLDREELCGKSA--PCALRLEVLLDRPLRVFHVEVEVTDINDNAPRFP 132 Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD--- 208 +S+ E S A+DAD+G+N+ + Y++ + F++D S D Sbjct: 133 AAYKNISIAE--SSLPGSRFPLEGASDADIGSNAQLSYSL---SPSEHFALDVKSPDDNL 187 Query: 209 ----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 + L LD E + +RLV+ A DGG P+ + T QL+I++ D NDNAP+F S+++ Sbjct: 188 KSLFLVLTHPLDRESLSEHRLVLTASDGGRPALTGTVQLVISVLDANDNAPQFNQSVYKV 247 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 + E+ G + RV A D D G N E +Y++ D +IDPR+G + +G L Sbjct: 248 QLPEDAAEGTLVARVAATDPDVGFNQEFSYSIVSSVPASQSD-AFSIDPRTGEIRLTGPL 306 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 D E +++L + A D G PP S + V + ED GT Sbjct: 307 DFEDVHQHELQIEARDKGTPPLSGHCSVILEVLDVNDNAPEVWVTSLSVPVPEDAALGTV 366 Query: 385 VVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 V L+ +D D + R+ + + G + + G + + + LD ++ Y + V Sbjct: 367 VALLSVSDRDSGPNGRVRCAVRPPSPFG--LVATFAGSYSLVLREALDRERVSEYEVEVR 424 Query: 443 ATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 A D G A +++ ++D N+ AP F A YT E+ G + + A D D Sbjct: 425 AEDGGAPPLRASRGLRVPVSDVNDNAPAFAQAVYTVLARENNAAGAELARLWARDPDEAG 484 Query: 501 NAQITYSL------SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554 N +++YS+ + S ++ ++G + + LD E + V A Sbjct: 485 NGRVSYSVAEGGAGTGSGSGSGWRPASSYVSVDAESGRLRALRPLDYEELQVLQFEVRAV 544 Query: 555 DGGVPSLSDTTDVEISVVDVNDNEP 579 D G P L V++ VVD NDN P Sbjct: 545 DAGEPPLCGNATVQLFVVDENDNAP 569 Score = 174 bits (423), Expect = 3e-41 Identities = 134/481 (27%), Positives = 216/481 (44%), Gaps = 48/481 (9%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI---EL 64 H ++ V D ND++P F S+ E + G+ A+D DIG NA++ Y++ E Sbjct: 116 HVEVEVTDINDNAPRFPAAYKNISIAESSLPGSRFPLEGASDADIGSNAQLSYSLSPSEH 175 Query: 65 VTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS 124 D +P+D ++ +F L+ LDRE ++ + +++ A+D Sbjct: 176 FALDVKSPDD----------NLKSLF--------LVLTHPLDRESLSEHRLVLTASDGGR 217 Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184 P L+ T + ++++D NDN PQF++ Y V + ED + ++A++ ATD DVG N Sbjct: 218 PA---LTGTVQLVISVLDANDNAPQFNQSVYKVQLPED--AAEGTLVARVAATDPDVGFN 272 Query: 185 SAIRYAIIGGNTQMQ---FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 Y+I+ Q FSID +G++ L LD+E V + L I A+D G+P S Sbjct: 273 QEFSYSIVSSVPASQSDAFSIDPRTGEIRLTGPLDFEDVHQHELQIEARDKGTPPLSGHC 332 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 +++ + DVNDNAP + + V E+ +G + + D D G N + + Sbjct: 333 SVILEVLDVNDNAPEVWVTSLSVPVPEDAALGTVVALLSVSDRDSGPNGRVRCAVRPPSP 392 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 G L T V LDRE ++Y++ V A DGG PP A+ Sbjct: 393 FG---LVATFAGSYSLVLREA-LDRERVSEYEVEVRAEDGGAPPLRASRGLRVPVSDVND 448 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI----------TGGNTR 409 F Y V E+ G + L A D DE + R+ Y + +G R Sbjct: 449 NAPAFAQAVYTVLARENNAAGAELARLWARDPDEAGNGRVSYSVAEGGAGTGSGSGSGWR 508 Query: 410 GRFSITSQNGR-GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYA 466 S S + G + +PLD+++ + V A D+G A VQ+ + D N+ A Sbjct: 509 PASSYVSVDAESGRLRALRPLDYEELQVLQFEVRAVDAGEPPLCGNATVQLFVVDENDNA 568 Query: 467 P 467 P Sbjct: 569 P 569 Score = 54.0 bits (124), Expect = 6e-05 Identities = 30/81 (37%), Positives = 43/81 (53%), Gaps = 4/81 (4%) Query: 271 PIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA 330 P G + +++A DAD G NA L Y + + G P + SG V T+ L+ Sbjct: 622 PAGQVVAKIRAVDADSGYNAWLRYELREPRGEG----PFRVGLYSGEVSTARALEEADGP 677 Query: 331 KYQLLVTATDGGDPPRSATAT 351 + +LL+ D G+PPRSATAT Sbjct: 678 RQRLLIVVRDHGEPPRSATAT 698 Score = 52.4 bits (120), Expect = 2e-04 Identities = 28/78 (35%), Positives = 43/78 (55%) Query: 170 VIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA 229 V+AKI+A DAD G N+ +RY + + F + SG+VS + L+ RL+I Sbjct: 626 VVAKIRAVDADSGYNAWLRYELREPRGEGPFRVGLYSGEVSTARALEEADGPRQRLLIVV 685 Query: 230 QDGGSPSRSNTTQLLINI 247 +D G P RS T L +++ Sbjct: 686 RDHGEPPRSATATLSVSL 703 Score = 49.2 bits (112), Expect = 0.002 Identities = 29/84 (34%), Positives = 43/84 (51%), Gaps = 1/84 (1%) Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653 A G V+++ A DAD G N + YEL + R EG F + SG + T +AL+ Sbjct: 621 APAGQVVAKIRAVDADSGYNAWLRYELR-EPRGEGPFRVGLYSGEVSTARALEEADGPRQ 679 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKI 677 L V D G PP+S+T + + + Sbjct: 680 RLLIVVRDHGEPPRSATATLSVSL 703 Score = 38.3 bits (85), Expect = 3.0 Identities = 25/92 (27%), Positives = 40/92 (43%), Gaps = 7/92 (7%) Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 AP G V + A D+D G NA + Y L + F + +G ++T + L+ Sbjct: 621 APAGQVVAKIRAVDADSGYNAWLRYELRE-------PRGEGPFRVGLYSGEVSTARALEE 673 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 L + RD G P S T + +S+V+ Sbjct: 674 ADGPRQRLLIVVRDHGEPPRSATATLSVSLVE 705 >UniRef50_O93508 Cluster: Paraxial protocadherin; n=6; Danio rerio|Rep: Paraxial protocadherin - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 950 Score = 200 bits (487), Expect = 6e-49 Identities = 160/566 (28%), Positives = 263/566 (46%), Gaps = 37/566 (6%) Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 I ++D+ND++P+F + +SE+ P+ A D D G N +Y ++ + Sbjct: 113 IEVKDINDHSPQFTRNETHLDISEDAPLNSRFPLDVAVDHDVGDNYIQSYHISHNSHFV- 171 Query: 305 VDLPITID-PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 V++ D +S + LDRET+ Y + VTATDGG P +S + T Sbjct: 172 VEVSTREDGEKSAELVLIKSLDRETEDFYTIEVTATDGGAPQKSGSTTLYIRVLDFNDNS 231 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR--- 420 F +VEL+ED P G+ V+ + A D D ++ EI G G S ++ + Sbjct: 232 PTFEHSSLKVELSEDSPIGSRVLKVHAFDPDAG--INGEIVYGFVEGSPSEVTRVFQIDL 289 Query: 421 --GLITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTA 476 G +T+ +D++ ++ Y L + A+D G S T ++I D N+ AP P T+ Sbjct: 290 ISGEVTLKDIVDYETKKSYELHIQASDLGANSVSSTCRAIVDIIDVNDNAPEIIIKPMTS 349 Query: 477 S------VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 + + E A + V ++S +D D G N + SL E H Q + T Sbjct: 350 TSDGVAFITEAAAEESFVALISTSDKDSGPNGYVRTSL------EGHEHFKLQQAYS-DT 402 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590 I T LDRE++S Y LTV + D G P I + D NDN P+F + +Y ++ Sbjct: 403 FMIITTTTLDRESISEYNLTVISEDLGTPPFKTVKHYTIRITDENDNPPLFSKSIYDVSV 462 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV-----IDPASGVIRTNKAL 645 +E+ + G+ ++ V A D D G NG++ Y L +GS + +DP SG + T ++ Sbjct: 463 IENNIPGSYMTTVVARDLDAGKNGKVSYSLVESKAPDGSSISTFVSVDPHSGSLYTLRSF 522 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS-P----PVFESDCLTFYISENS 700 D E++ A D G P SST ++ +++ D ND+ P PV ++ I N+ Sbjct: 523 DFETLKDVQFSVKATDKGFPSLSSTTLIQVRVVDDNDNFPYFTYPVLRNNSAEIPIPMNA 582 Query: 701 PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760 G ++ A D D G N+ ++Y I D++ FS++ G + L + Sbjct: 583 NTGYLALKVAAKDEDSGINSELNYHIL-EDEAKLFSIDKNTG--EIILKRKLTASCGEIL 639 Query: 761 KKYELVIRAASPPLWNDVRVEILVTD 786 + Y V+ A PL + + +VTD Sbjct: 640 QIYVSVVDGAREPLSSSANIRFIVTD 665 Score = 195 bits (475), Expect = 2e-47 Identities = 167/602 (27%), Positives = 254/602 (42%), Gaps = 27/602 (4%) Query: 97 GALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT 156 G L +DREK+ + + T S + + + D ND+ PQF+ Sbjct: 72 GLLTVGEVIDREKLCQRSPQCLITFDVVAFSKEKFQLIHVEIEVKDINDHSPQFTRNETH 131 Query: 157 VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL-----SGDVSL 211 + + ED + N A D DVG N Y I N+ + + S ++ L Sbjct: 132 LDISEDAPL--NSRFPLDVAVDHDVGDNYIQSYHI-SHNSHFVVEVSTREDGEKSAELVL 188 Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271 +K+LD E Y + + A DGG+P +S +T L I + D NDN+P F S + +SE+ P Sbjct: 189 IKSLDRETEDFYTIEVTATDGGAPQKSGSTTLYIRVLDFNDNSPTFEHSSLKVELSEDSP 248 Query: 272 IGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK 331 IG +++V A+D D G+N E+ Y + V ID SG V +D ET+ Sbjct: 249 IGSRVLKVHAFDPDAGINGEIVYGFVEGS-PSEVTRVFQIDLISGEVTLKDIVDYETKKS 307 Query: 332 YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF----MPGQYE-VELAEDEPPGTPVV 386 Y+L + A+D G S+T M + V + V Sbjct: 308 YELHIQASDLGANSVSSTCRAIVDIIDVNDNAPEIIIKPMTSTSDGVAFITEAAAEESFV 367 Query: 387 TLTATDADEDNRLHYEITGGNTRGRFSI-TSQNGRGLITVAQPLDFKQERRYVLTVSATD 445 L +T + Y T F + + + +I LD + Y LTV + D Sbjct: 368 ALISTSDKDSGPNGYVRTSLEGHEHFKLQQAYSDTFMIITTTTLDRESISEYNLTVISED 427 Query: 446 SGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503 G I ITD N+ P+F + Y SV E+ G+ + V A D D G N + Sbjct: 428 LGTPPFKTVKHYTIRITDENDNPPLFSKSIYDVSVIENNIPGSYMTTVVARDLDAGKNGK 487 Query: 504 ITYSLSSEISNEAVAHHDQQFV-INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 ++YSL S FV ++P +G++ T + D ET+ +V A D G PSLS Sbjct: 488 VSYSLVE--SKAPDGSSISTFVSVDPHSGSLYTLRSFDFETLKDVQFSVKATDKGFPSLS 545 Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIME-----DALVGTSVSQVGATDADVGLNGRIH 617 TT +++ VVD NDN P F + N E +A G +V A D D G+N ++ Sbjct: 546 STTLIQVRVVDDNDNFPYFTYPVLRNNSAEIPIPMNANTGYLALKVAAKDEDSGINSELN 605 Query: 618 YELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 Y + + E F ID +G I + L + +DG P SS+ + + Sbjct: 606 YHI--LEDEAKLFSIDKNTGEIILKRKLTASCGEILQIYVSVVDGAREPLSSSANIRFIV 663 Query: 678 ED 679 D Sbjct: 664 TD 665 Score = 188 bits (457), Expect = 3e-45 Identities = 150/535 (28%), Positives = 248/535 (46%), Gaps = 33/535 (6%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSI-TSQNGR--G 421 F + ++++ED P + A D D DN + N+ + T ++G Sbjct: 125 FTRNETHLDISEDAPLNSRFPLDVAVDHDVGDNYIQSYHISHNSHFVVEVSTREDGEKSA 184 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVF 479 + + + LD + E Y + V+ATD G +S + + I + D N+ +P FE++ + Sbjct: 185 ELVLIKSLDRETEDFYTIEVTATDGGAPQKSGSTTLYIRVLDFNDNSPTFEHSSLKVELS 244 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 ED+PIG+ VL V A D D GIN +I Y +E + F I+ +G +T ++ Sbjct: 245 EDSPIGSRVLKVHAFDPDAGINGEIVYGFVEGSPSEVT----RVFQIDLISGEVTLKDIV 300 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP--VFKQQLYTAN----IMED 593 D ET Y L + A D G S+S T + ++DVNDN P + K T++ I E Sbjct: 301 DYETKKSYELHIQASDLGANSVSSTCRAIVDIIDVNDNAPEIIIKPMTSTSDGVAFITEA 360 Query: 594 ALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATH 653 A + V+ + +D D G NG + L+ + + +I T LDRES++ + Sbjct: 361 AAEESFVALISTSDKDSGPNGYVRTSLEGHEHFKLQQAYSDTFMIITTT-TLDRESISEY 419 Query: 654 DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHD 713 +L ++ D GTPP + I+I D ND+PP+F + EN+ G+ + + A D Sbjct: 420 NLTVISEDLGTPPFKTVKHYTIRITDENDNPPLFSKSIYDVSVIENNIPGSYMTTVVARD 479 Query: 714 PDEGPNAVVHYSI--KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS 771 D G N V YS+ D +S S L T+ D+E+ K + ++A Sbjct: 480 LDAGKNGKVSYSLVESKAPDGSSISTFVSVDPHSGSLYTLRSFDFET-LKDVQFSVKATD 538 Query: 772 ---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC-FPVGPFG-----RVPAYDAD 822 P L + +++ V D NDN P + ++ NN + P+ +V A D D Sbjct: 539 KGFPSLSSTTLIQVRVVDDNDNFPYFT-YPVLRNNSAEIPIPMNANTGYLALKVAAKDED 597 Query: 823 --VTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE 875 + +L Y IL + A L +++ TG + L +L + ++ + VSV DG E Sbjct: 598 SGINSELNYHILE-DEAKLFSIDKNTGEIILKRKLTASCGEILQIYVSVVDGARE 651 Score = 184 bits (447), Expect = 4e-44 Identities = 165/595 (27%), Positives = 254/595 (42%), Gaps = 56/595 (9%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 IH +I V D NDHSP F + + E A + A D D+G N Y I Sbjct: 109 IHVEIEVKDINDHSPQFTRNETHLDISEDAPLNSRFPLDVAVDHDVGDNYIQSYHIS--- 165 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASP 125 V+ R DG +S L+ SLDRE YT+ V ATD +P Sbjct: 166 -------------HNSHFVVEVSTREDGEKSAELVLIKSLDRETEDFYTIEVTATDGGAP 212 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 + S + T+++ ++D NDN P F + V + ED + + K+ A D D G N Sbjct: 213 ---QKSGSTTLYIRVLDFNDNSPTFEHSSLKVELSEDSPIGSR--VLKVHAFDPDAGING 267 Query: 186 AIRYAIIGGNTQ---MQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 I Y + G+ F ID +SG+V+L +DYE +SY L I+A D G+ S S+T + Sbjct: 268 EIVYGFVEGSPSEVTRVFQIDLISGEVTLKDIVDYETKKSYELHIQASDLGANSVSSTCR 327 Query: 243 LLINIRDVNDNAPRFY------TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 +++I DVNDNAP TS ++E + + D D G N Y Sbjct: 328 AIVDIIDVNDNAPEIIIKPMTSTSDGVAFITEAAAEESFVALISTSDKDSGPNG---YVR 384 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 T + + L + + T+ LDRE+ ++Y L V + D G PP Sbjct: 385 TSLEGHEHFKLQQAYSD-TFMIITTTTLDRESISEYNLTVISEDLGTPPFKTVKHYTIRI 443 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSI 414 F Y+V + E+ PG+ + T+ A D D ++ ++ Y + SI Sbjct: 444 TDENDNPPLFSKSIYDVSVIENNIPGSYMTTVVARDLDAGKNGKVSYSLVESKAPDGSSI 503 Query: 415 TS----QNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDAN-NYA- 466 ++ G + + DF+ + +V ATD G S T ++Q+ + D N N+ Sbjct: 504 STFVSVDPHSGSLYTLRSFDFETLKDVQFSVKATDKGFPSLSSTTLIQVRVVDDNDNFPY 563 Query: 467 ---PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523 PV N + +A G L V+A D D GIN+++ Y + + +EA + Sbjct: 564 FTYPVLRNNSAEIPIPMNANTGYLALKVAAKDEDSGINSELNYHI---LEDEA-----KL 615 Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578 F I+ TG I + L + V+ DG LS + ++ V D E Sbjct: 616 FSIDKNTGEIILKRKLTASCGEILQIYVSVVDGAREPLSSSANIRFIVTDTGAQE 670 Score = 149 bits (362), Expect = 8e-34 Identities = 147/546 (26%), Positives = 238/546 (43%), Gaps = 49/546 (8%) Query: 377 EDEPPGTPVVTLTAT---DADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD--- 430 E++ PGT + L+ D ED ++ + I + GL+TV + +D Sbjct: 28 EEDAPGTEIGNLSQDLKIDPSEDPETSFKFIQTSNS---IIDMRQMDGLLTVGEVIDREK 84 Query: 431 -FKQERRYVLTVSATD-SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 ++ + ++T S + V+I + D N+++P F + EDAP+ + Sbjct: 85 LCQRSPQCLITFDVVAFSKEKFQLIHVEIEVKDINDHSPQFTRNETHLDISEDAPLNSRF 144 Query: 489 LVVSATDSDVGINAQITYSLS--SEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 + A D DVG N +Y +S S E D + ++ + K LDRET Sbjct: 145 PLDVAVDHDVGDNYIQSYHISHNSHFVVEVSTREDGE-----KSAELVLIKSLDRETEDF 199 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y + VTA DGG P S +T + I V+D NDN P F+ + ED+ +G+ V +V A Sbjct: 200 YTIEVTATDGGAPQKSGSTTLYIRVLDFNDNSPTFEHSSLKVELSEDSPIGSRVLKVHAF 259 Query: 607 DADVGLNGRIHYELDPKDREEGS--FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 D D G+NG I Y E + F ID SG + +D E+ +++L A D G Sbjct: 260 DPDAGINGEIVYGFVEGSPSEVTRVFQIDLISGEVTLKDIVDYETKKSYELHIQASDLGA 319 Query: 665 PPQSSTVIVHIKIEDINDSPP-------VFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 SST + I D+ND+ P SD + F I+E + + + I D D G Sbjct: 320 NSVSSTCRAIVDIIDVNDNAPEIIIKPMTSTSDGVAF-ITEAAAEESFVALISTSDKDSG 378 Query: 718 PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPL 774 PN V S++G + F L+ + SD ++T LD ES +Y L + + +PP Sbjct: 379 PNGYVRTSLEGHE---HFKLQ-QAYSDTFMIITTTTLDRES-ISEYNLTVISEDLGTPPF 433 Query: 775 WNDVRVEILVTDVNDNAPVMK----DFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYR 830 I +TD NDN P+ D +I NN + R DA K+ Y Sbjct: 434 KTVKHYTIRITDENDNPPLFSKSIYDVSVIENNIPGSYMTTVVAR--DLDAGKNGKVSYS 491 Query: 831 IL-----SGNN-ANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLS 883 ++ G++ + + ++ +GS+ + K V TD G + + + Sbjct: 492 LVESKAPDGSSISTFVSVDPHSGSLYTLRSFDFETLKDVQFSVKATDKGFPSLSSTTLIQ 551 Query: 884 VRLITE 889 VR++ + Sbjct: 552 VRVVDD 557 >UniRef50_UPI0000660F9A Cluster: Homolog of Brachydanio rerio "Cadherin-related neuronal receptor variable 7.; n=1; Takifugu rubripes|Rep: Homolog of Brachydanio rerio "Cadherin-related neuronal receptor variable 7. - Takifugu rubripes Length = 718 Score = 199 bits (486), Expect = 8e-49 Identities = 168/583 (28%), Positives = 264/583 (45%), Gaps = 56/583 (9%) Query: 136 IHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG- 194 I V ++D NDN PQF + + E + + A D D+G+NS Y + Sbjct: 21 IEVELLDINDNAPQFRRDAIHLDISE--ATPRGERFSLSNAVDPDIGSNSVKTYQLSEND 78 Query: 195 --NTQMQFSIDSLS-GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251 N ++Q + D+ L TLD EQ + L++ A DGG P+RS T +++++ D N Sbjct: 79 YFNIEVQTGREGTKFADLILKTTLDREQQSVHNLILTAVDGGKPARSGTASVIVHVMDTN 138 Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY---------TMTDK--- 299 DN+P F + + EN PIG ++ + A D DEG N++LTY T+ + Sbjct: 139 DNSPTFDQINYNLEIMENSPIGSLVIHLNATDLDEGSNSDLTYSYNLGLDVKTLNQRKMR 198 Query: 300 -DYTGNVDLPITIDPRSGWVYTSGQLDRE----TQAK-YQLLVTATDGGDPPRSATATXX 353 D N + ++ +G +Y ++DRE T+A Y L D P R Sbjct: 199 LDIIANKKY-LDVNKETGELYVVEKIDREYICSTKASCYLKLEVILD--SPVR--IFNIE 253 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS 413 F ++++E P G A D D + + + F+ Sbjct: 254 VEILDINDNAPQFRRDIIHLDISEATPRGERFSLSNAVDPDVGSN-SVKTYYLSESEYFN 312 Query: 414 ITSQNGR-----GLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYA 466 I Q GR + + + LD +Q+ + L ++A D G RS TA V + + D N+ + Sbjct: 313 IEVQTGRDGSKFSELILKRALDREQQSVHNLILTAVDGGKPARSGTASVIVRVLDTNDNS 372 Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 P F+ + Y + E++PIG+ V+ ++ATD D G N+ +TYS S + + + F + Sbjct: 373 PTFDKSNYNLEIMENSPIGSLVIHLNATDLDEGSNSDLTYSYSLYTAEKT----QETFYL 428 Query: 527 NPQTGAITTN--------KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578 NP TG IT K+ D E +L + ARD G P LS V I +VD NDN Sbjct: 429 NPSTGEITVKGLLNYEDFKIYDMEIEKEFLFHIEARDSGSPPLSSNVSVHIIIVDQNDNA 488 Query: 579 PVFKQQLYT-ANIMEDAL-----VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632 PV +++E+ + G+ V++V A D D N RI Y+L + + F + Sbjct: 489 PVIVSPWRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQL-LQVTDATLFSL 547 Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675 D +G IRT + L VA D G P S+TV + + Sbjct: 548 DQYNGEIRTMRMFSYRDPRHQRLVVVAKDNGNPALSATVTIKL 590 Score = 174 bits (424), Expect = 3e-41 Identities = 163/602 (27%), Positives = 270/602 (44%), Gaps = 67/602 (11%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ +LD ND++P F + E G A D DIG N+ Y +L D Sbjct: 22 EVELLDINDNAPQFRRDAIHLDISEATPRGERFSLSNAVDPDIGSNSVKTY--QLSENDY 79 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N E VQ R + L+ + +LDRE+ + + +++ A D P Sbjct: 80 FNIE------------VQ-TGREGTKFADLILKTTLDREQQSVHNLILTAVDGGKPAR-- 124 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S TA++ V+++D NDN P F + Y + + E+ + ++ + ATD D G+NS + Y Sbjct: 125 -SGTASVIVHVMDTNDNSPTFDQINYNLEIMENSPI--GSLVIHLNATDLDEGSNSDLTY 181 Query: 190 AI-----IGGNTQMQFSIDSL-----------SGDVSLVKTLDYEQVRSYRLVIRAQ-DG 232 + + Q + +D + +G++ +V+ +D E + S + + + Sbjct: 182 SYNLGLDVKTLNQRKMRLDIIANKKYLDVNKETGELYVVEKIDREYICSTKASCYLKLEV 241 Query: 233 GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292 S + + I D+NDNAP+F + +SE P G A D D G N+ Sbjct: 242 ILDSPVRIFNIEVEILDINDNAPQFRRDIIHLDISEATPRGERFSLSNAVDPDVGSNSVK 301 Query: 293 TYTMTDKDYTGNVDLPITID-PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 TY +++ +Y N+++ D + + LDRE Q+ + L++TA DGG P RS TA+ Sbjct: 302 TYYLSESEYF-NIEVQTGRDGSKFSELILKRALDREQQSVHNLILTAVDGGKPARSGTAS 360 Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE----DNRLHYEI-TGG 406 F Y +E+ E+ P G+ V+ L ATD DE D Y + T Sbjct: 361 VIVRVLDTNDNSPTFDKSNYNLEIMENSPIGSLVIHLNATDLDEGSNSDLTYSYSLYTAE 420 Query: 407 NTRGRFSITSQNG----RGLITVA--QPLDFKQERRYVLTVSATDSGG--RSDTAMVQIN 458 T+ F + G +GL+ + D + E+ ++ + A DSG S V I Sbjct: 421 KTQETFYLNPSTGEITVKGLLNYEDFKIYDMEIEKEFLFHIEARDSGSPPLSSNVSVHII 480 Query: 459 ITDANNYAPVFENAPYTA--SVFED-----APIGTTVLVVSATDSDVGINAQITYSLSSE 511 I D N+ APV +P+ A SV E+ G+ V V A D D N++ITY L + Sbjct: 481 IVDQNDNAPVIV-SPWRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQL-LQ 538 Query: 512 ISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571 +++ + F ++ G I T ++ L V A+D G P+LS T +++S Sbjct: 539 VTDATL------FSLDQYNGEIRTMRMFSYRDPRHQRLVVVAKDNGNPALSATVTIKLST 592 Query: 572 VD 573 V+ Sbjct: 593 VE 594 Score = 167 bits (406), Expect = 4e-39 Identities = 161/599 (26%), Positives = 272/599 (45%), Gaps = 61/599 (10%) Query: 373 VELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGR-----GLITV 425 ++++E P G A D D ++ Y+++ + F+I Q GR + + Sbjct: 42 LDISEATPRGERFSLSNAVDPDIGSNSVKTYQLSENDY---FNIEVQTGREGTKFADLIL 98 Query: 426 AQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 LD +Q+ + L ++A D G RS TA V +++ D N+ +P F+ Y + E++P Sbjct: 99 KTTLDREQQSVHNLILTAVDGGKPARSGTASVIVHVMDTNDNSPTFDQINYNLEIMENSP 158 Query: 484 IGTTVLVVSATDSDVGINAQITYS----LSSEISNEAVAHHD-----QQFVINPQTGAIT 534 IG+ V+ ++ATD D G N+ +TYS L + N+ D + +N +TG + Sbjct: 159 IGSLVIHLNATDLDEGSNSDLTYSYNLGLDVKTLNQRKMRLDIIANKKYLDVNKETGELY 218 Query: 535 TNKLLDRETM-----SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589 + +DRE + S YL D V + +E+ ++D+NDN P F++ + + Sbjct: 219 VVEKIDREYICSTKASCYLKLEVILDSPVRIFN----IEVEILDINDNAPQFRRDIIHLD 274 Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG-------VIRTN 642 I E G S A D DVG N Y L E F I+ +G + Sbjct: 275 ISEATPRGERFSLSNAVDPDVGSNSVKTYYLS----ESEYFNIEVQTGRDGSKFSELILK 330 Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 +ALDRE + H+L A+DGG P +S T V +++ D ND+ P F+ I ENSPI Sbjct: 331 RALDREQQSVHNLILTAVDGGKPARSGTASVIVRVLDTNDNSPTFDKSNYNLEIMENSPI 390 Query: 703 GTTIGEIRAHDPDEGPNAVVHYSIK---GGDDSNSFSLETRQGSDKAE-LVTMVDLD-YE 757 G+ + + A D DEG N+ + YS +F L G + L+ D Y+ Sbjct: 391 GSLVIHLNATDLDEGSNSDLTYSYSLYTAEKTQETFYLNPSTGEITVKGLLNYEDFKIYD 450 Query: 758 SPRKK---YELVIR-AASPPLWNDVRVEILVTDVNDNAPVM-----KDFQIIFNNYKDCF 808 +K + + R + SPPL ++V V I++ D NDNAPV+ ++ Sbjct: 451 MEIEKEFLFHIEARDSGSPPLSSNVSVHIIIVDQNDNAPVIVSPWRAQGSVVEEKIPRST 510 Query: 809 PVGPF-GRVPAYDADV--TDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATM 865 G +V A D D ++ Y++L +A L L++ G + + P+ + Sbjct: 511 DKGSLVAKVIALDVDSVHNSRITYQLLQVTDATLFSLDQYNGEIRTMRMFSYRDPRHQRL 570 Query: 866 EVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAE-QFLSPLLGFFIDGLAAI 923 V D N + ++++L T E + + + L ++ E S L + + GL ++ Sbjct: 571 VVVAKDNGNPALS-ATVTIKLSTVETAVKAYS-DLTEVPLEYDIFSDLNLYLVIGLGSV 627 Score = 160 bits (388), Expect = 6e-37 Identities = 128/496 (25%), Positives = 216/496 (43%), Gaps = 37/496 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIEL-VTADT 69 ++V+D ND+SP F+ Y + E + G+ V+ L ATD D G N+++ Y+ L + T Sbjct: 132 VHVMDTNDNSPTFDQINYNLEIMENSPIGSLVIHLNATDLDEGSNSDLTYSYNLGLDVKT 191 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 LN + ++ +G L +DRE + + + + D Sbjct: 192 LNQRKMRLDIIANKKYLD----VNKETGELYVVEKIDREYIC--STKASCYLKLEVILDS 245 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 I V I+D NDN PQF + + E + + A D DVG+NS Y Sbjct: 246 PVRIFNIEVEILDINDNAPQFRRDIIHLDISE--ATPRGERFSLSNAVDPDVGSNSVKTY 303 Query: 190 AIIGG---NTQMQFSID-SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 + N ++Q D S ++ L + LD EQ + L++ A DGG P+RS T +++ Sbjct: 304 YLSESEYFNIEVQTGRDGSKFSELILKRALDREQQSVHNLILTAVDGGKPARSGTASVIV 363 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG-N 304 + D NDN+P F S + + EN PIG ++ + A D DEG N++LTY+ + YT Sbjct: 364 RVLDTNDNSPTFDKSNYNLEIMENSPIGSLVIHLNATDLDEGSNSDLTYSYS--LYTAEK 421 Query: 305 VDLPITIDPRSGWVYTSGQL--------DRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 ++P +G + G L D E + ++ + A D G PP S+ + Sbjct: 422 TQETFYLNPSTGEITVKGLLNYEDFKIYDMEIEKEFLFHIEARDSGSPPLSSNVSVHIII 481 Query: 357 XXXXXXXXXFM-PGQYEVELAEDEPP-----GTPVVTLTATDAD--EDNRLHYEITGGNT 408 + P + + + E++ P G+ V + A D D ++R+ Y++ Sbjct: 482 VDQNDNAPVIVSPWRAQGSVVEEKIPRSTDKGSLVAKVIALDVDSVHNSRITYQLLQVTD 541 Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468 FS+ NG I + ++ R L V A D+G + +A V I ++ Sbjct: 542 ATLFSLDQYNGE--IRTMRMFSYRDPRHQRLVVVAKDNGNPALSATVTIKLSTVETAVKA 599 Query: 469 FEN---APYTASVFED 481 + + P +F D Sbjct: 600 YSDLTEVPLEYDIFSD 615 Score = 130 bits (315), Expect = 4e-28 Identities = 119/438 (27%), Positives = 182/438 (41%), Gaps = 30/438 (6%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 +++ + D N+ AP F + E P G + +A D D+G N+ TY LS N Sbjct: 21 IEVELLDINDNAPQFRRDAIHLDISEATPRGERFSLSNAVDPDIGSNSVKTYQLS---EN 77 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 + Q + + LDRE S + L +TA DGG P+ S T V + V+D Sbjct: 78 DYFNIEVQTGREGTKFADLILKTTLDREQQSVHNLILTAVDGGKPARSGTASVIVHVMDT 137 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE----LDPKDREEGSF 630 NDN P F Q Y IME++ +G+ V + ATD D G N + Y LD K + Sbjct: 138 NDNSPTFDQINYNLEIMENSPIGSLVIHLNATDLDEGSNSDLTYSYNLGLDVKTLNQRKM 197 Query: 631 VID-----------PASGVIRTNKALDRESVATHDLKA-VAIDGGTPPQSSTVIVHIKIE 678 +D +G + + +DRE + + + ++ + ++I Sbjct: 198 RLDIIANKKYLDVNKETGELYVVEKIDREYICSTKASCYLKLEVILDSPVRIFNIEVEIL 257 Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738 DIND+ P F D + ISE +P G A DPD G N+V Y + + N Sbjct: 258 DINDNAPQFRRDIIHLDISEATPRGERFSLSNAVDPDVGSNSVKTYYLSESEYFNIEVQT 317 Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMK 795 R GS +EL+ LD E + + L++ A P V + V D NDN+P Sbjct: 318 GRDGSKFSELILKRALDREQ-QSVHNLILTAVDGGKPARSGTASVIVRVLDTNDNSPTFD 376 Query: 796 DFQIIFNNYKDCFPVGPFG-RVPAYDADVTDK----LQYRILSGNNA-NLILLNETTGSM 849 ++ P+G + A D D Y + + LN +TG + Sbjct: 377 KSNYNLEIMENS-PIGSLVIHLNATDLDEGSNSDLTYSYSLYTAEKTQETFYLNPSTGEI 435 Query: 850 TLSPQLNTNVPKLATMEV 867 T+ LN K+ ME+ Sbjct: 436 TVKGLLNYEDFKIYDMEI 453 Score = 105 bits (253), Expect = 1e-20 Identities = 86/281 (30%), Positives = 130/281 (46%), Gaps = 28/281 (9%) Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625 ++E+ ++D+NDN P F++ +I E G S A D D+G N Y+L D Sbjct: 20 NIEVELLDINDNAPQFRRDAIHLDISEATPRGERFSLSNAVDPDIGSNSVKTYQLSENDY 79 Query: 626 -----EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680 + G A +++T LDRE + H+L A+DGG P +S T V + + D Sbjct: 80 FNIEVQTGREGTKFADLILKT--TLDREQQSVHNLILTAVDGGKPARSGTASVIVHVMDT 137 Query: 681 NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD--------- 731 ND+ P F+ I ENSPIG+ + + A D DEG N+ + YS G D Sbjct: 138 NDNSPTFDQINYNLEIMENSPIGSLVIHLNATDLDEGSNSDLTYSYNLGLDVKTLNQRKM 197 Query: 732 -----SNSFSLETRQGSDKAELVTMVDLDYESPRKK---YELVIRAASPPLWNDVRVEIL 783 +N L+ + + + +V +D +Y K +L + SP ++ VEIL Sbjct: 198 RLDIIANKKYLDVNKETGELYVVEKIDREYICSTKASCYLKLEVILDSPVRIFNIEVEIL 257 Query: 784 VTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDADV 823 D+NDNAP + II + + P G F A D DV Sbjct: 258 --DINDNAPQFRR-DIIHLDISEATPRGERFSLSNAVDPDV 295 >UniRef50_UPI0000DB7642 Cluster: PREDICTED: similar to Cad89D CG14900-PA; n=1; Apis mellifera|Rep: PREDICTED: similar to Cad89D CG14900-PA - Apis mellifera Length = 1730 Score = 198 bits (483), Expect = 2e-48 Identities = 222/831 (26%), Positives = 362/831 (43%), Gaps = 97/831 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V D NDH+P F Y +V E G T+ I V D Sbjct: 108 VYVEDINDHAPQFVDAPYHVTVDELTPVGVTIFR----------------GIHAVDGDKP 151 Query: 71 NPEDAXXXXXXXXXXVQDVFRID-GRSGALLTRASLDREKVAR-YTVLVKATDQASPVSD 128 N ++ + F ++ G AL+ R +D + R +T+++ ATD+ +P Sbjct: 152 NTPNSDVHYAIVKGNEEGKFSLESGHRTALILREPVDYDNGDREFTLVIAATDRGAPA-- 209 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKI------KATDADVG 182 R ++T T+ + ++D++D P+F+ Y + E + ++P+ +I +ATD D Sbjct: 210 RTTNT-TVRITVLDNDDLDPKFTRDVYKAKIYEFYPMPEHPIFVRINFSTPIQATDRDRD 268 Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-----YRLVIRAQDGGSPSR 237 ++ IRY I GN + F +D + + L + +D + R+ + L I A +P R Sbjct: 269 IDAPIRYDIASGNERGFFHLDPKNATLYLKRAIDLDAERNLPSNTFTLQIHASQVDNPLR 328 Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297 S ++ + + D+NDN P F L+ S+ EN+P G+S+++V A D D+G N + Y + Sbjct: 329 SGVARVEVEVLDLNDNLPEFEVDLYNISIVENLPNGFSVLQVIARDRDQGENGQFDYELV 388 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGGD---PPRSATATX 352 D +G ++D RSGW+ Q LDRE + + ++ V A + PR+ +++ Sbjct: 389 DP--SG----AFSVDARSGWLTVRDQSVLDRERRDRLRMRVVAVEKRPSVVAPRNGSSSS 442 Query: 353 XXXXXXXXXXXX-----XFMPGQ-YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEI- 403 F+PG YE+ D GT + + A D D + + Y + Sbjct: 443 SSVDVDVTLLDANDNNPIFVPGNLYELVARSDSKVGTVLGQVHAVDDDLGPNGMVRYRLQ 502 Query: 404 -TGGNTRGRFSITSQNGRGLITVAQ-PLDFKQERRYVLTVSATD-----SGGRSDTAMVQ 456 G +T G I+V++ P+ E R+ + V A D S R A+V Sbjct: 503 KPGNSTARTPPFAVDEVTGTISVSESPI---LEGRHAIFVEAADQPANPSERRISLAVVT 559 Query: 457 INI--TDA-NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513 +++ +D + P F APY V + P+GT+V + D+ V N + Y L Sbjct: 560 VDVFRSDGPESLEPDFVGAPYEFWVGANVPVGTSVGQIRLNDA-VKTN-DLIYDLLHSY- 616 Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 E V F + ++G IT + ++R S Y D L T+V I VVD Sbjct: 617 EEGV-----PFAVEERSGTITVVEEIERFDRSIYDFEAIVTD--ERDLMLITNVSIHVVD 669 Query: 574 VNDNEPVFKQQLYTANI-------MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE 626 ND +F + TA + M A +G + Q G A + ++ +D Sbjct: 670 PNDERGIFTRGTTTAPLVFHARENMAGAYIGQILPQNGTGSATPATR---FFIVNQQDVP 726 Query: 627 EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686 + S D G + K LDRE+ + + +A + V + + D ND P Sbjct: 727 DISITED---GALYAPKGLDREARQNYSITVIA---ESQRGVGVFQVSVIVLDENDHAPE 780 Query: 687 FESDCLTFYISENSPIGTTIG---EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 F S I+ENSP GT + I A D DEG N +++ G+ S F + G Sbjct: 781 FTSPLYEGRITENSPPGTKVNLSIPITATDKDEGINQNFVFTLH-GERSELFRIHPTTGL 839 Query: 744 DKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAPV 793 E + LD E+ R Y I A + L ++ R+ I VTDVNDN+PV Sbjct: 840 VYFEGIDDRTLDREA-RANYSFTIVAKDNGGLTSESRLRITVTDVNDNSPV 889 Score = 168 bits (409), Expect = 2e-39 Identities = 202/761 (26%), Positives = 329/761 (43%), Gaps = 107/761 (14%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTV---LTLKATDQDIGKNAEVEYTIELVTADT 69 VLD NDH+P F YE + E + GT V + + ATD+D G N +T+ ++ Sbjct: 771 VLDENDHAPEFTSPLYEGRITENSPPGTKVNLSIPITATDKDEGINQNFVFTLHGERSEL 830 Query: 70 --LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 ++P D S ++ + + +R + V + SPV Sbjct: 831 FRIHPTTGLVYFEGIDDRTLDREARANYSFTIVAKDNGGLTSESRLRITVTDVNDNSPVF 890 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS-----------------VTDNPV 170 R+ V + ++ D F +D S V +N Sbjct: 891 IRMIVLPEQGVRVSNEADTEASFEGNDVVADTADDTSGAGGDRAASGRRSPLLLVPENAT 950 Query: 171 IA----KIKATDADVGANSAIRYAII-----GGNTQMQ----------FSIDSLSGDVSL 211 I ++ A D D G N+AI Y+++ G T ++ F +D SG++S+ Sbjct: 951 IGAPIIRLLAEDRDEGTNAAITYSLVNETVSGDETVVESRLDTTNRRYFHLDPRSGEISV 1010 Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP 271 + L E + R + A+D G + T + I++ DVND+ P F S + V+E Sbjct: 1011 ARGLTAET--NVRFLALAKDPGGLFDNITVR--IHVVDVNDHPPSFDKSWYTFDVAEGTY 1066 Query: 272 IGYSIVRVQAYDADEGVNAELTYTMTDKDYTG--NVDLPITIDPRSGWVYTSGQLDRETQ 329 GY++ RV+A DAD G NA +TY +T +D +G NV + P G + +G LDRET Sbjct: 1067 KGYTLGRVRAVDADHGRNANVTYELTTRDDSGVGNVSRIFEVGPGEGVIRVTGVLDRETV 1126 Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ-------------YEVELA 376 ++LLVTA D G P S+T F Y + Sbjct: 1127 PVHRLLVTARDNGVPRLSSTVEVEVNVLDVNDNPPVFHDYDEIEKDENGDPLPVYHASVL 1186 Query: 377 EDEPPGTPVVTLTATDAD----EDNRLHYEIT--GGNTRGRFSITSQNGRGLITVAQPLD 430 E+ P G+ V+ + A D D + + +++ G + F+I S+ G +ITV LD Sbjct: 1187 ENSPVGSRVIKVRADDTDFAGNGNGLILFDLNHPGKLEKQWFAIDSKEG--VITVVGDLD 1244 Query: 431 FKQERRYVLTVSATDSGGR---SDTAMVQINITDANN-------YAPVFENAPYTASVFE 480 ++++R + L V+A+D G + TA V + +++ ++ AP F++ Y V E Sbjct: 1245 YERQRSHRLVVTASDLGSPVSLTSTAAVIVAVSNEDDGEEGTTERAPTFKHRYYEVEVEE 1304 Query: 481 DAPIGTTVLVVS-ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 + + V + A DSDV + + YS+ +++E A Q F I+P+ G++ + Sbjct: 1305 NVEVPVLVARLELADDSDVR-DEHVRYSI---VADETKAR--QLFSIDPRNGSLYLTTGV 1358 Query: 540 DRETMSGYLLTVTA---RDG-GVPSL-------------SDTTDVEISVVDVNDNEPVFK 582 DRE Y V + G G+P + + V + V DVNDN P FK Sbjct: 1359 DREVNDRYEAKVRVDRVKIGRGMPVMIYPVVGERLNGLAPNEARVVVRVKDVNDNAPRFK 1418 Query: 583 Q--QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640 + A + A G V +V A D D G N I Y++ ++ + F IDP SG +R Sbjct: 1419 SRGRPILAAVPTTAHYGYEVVKVEAEDPDEGANAEIRYQILGRE-DAPRFAIDPLSGQVR 1477 Query: 641 TNKALDRES--VATHDLKAVAIDGGTPPQSSTVIVHIKIED 679 + + R++ V D+KA G +SS V + + D Sbjct: 1478 SVASFGRDAGRVFGFDVKATDRRGAEDGRSSIANVFVYVLD 1518 Score = 168 bits (408), Expect = 2e-39 Identities = 161/555 (29%), Positives = 247/555 (44%), Gaps = 63/555 (11%) Query: 377 EDEPPGTPVVTLTATDADEDNR-------LHYEITGGNTRGRFSITSQNGR--------G 421 E+ G P++ L A D DE ++ ++G T + + N R G Sbjct: 947 ENATIGAPIIRLLAEDRDEGTNAAITYSLVNETVSGDETVVESRLDTTNRRYFHLDPRSG 1006 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 I+VA+ L + R++ A D GG D V+I++ D N++ P F+ + YT V E Sbjct: 1007 EISVARGLTAETNVRFLAL--AKDPGGLFDNITVRIHVVDVNDHPPSFDKSWYTFDVAEG 1064 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 G T+ V A D+D G NA +TY L++ + V + + F + P G I +LDR Sbjct: 1065 TYKGYTLGRVRAVDADHGRNANVTYELTTR-DDSGVGNVSRIFEVGPGEGVIRVTGVLDR 1123 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ-------------QLYTA 588 ET+ + L VTARD GVP LS T +VE++V+DVNDN PVF +Y A Sbjct: 1124 ETVPVHRLLVTARDNGVPRLSSTVEVEVNVLDVNDNPPVFHDYDEIEKDENGDPLPVYHA 1183 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGR--IHYELD-PKDREEGSFVIDPASGVIRTNKAL 645 +++E++ VG+ V +V A D D NG I ++L+ P E+ F ID GVI L Sbjct: 1184 SVLENSPVGSRVIKVRADDTDFAGNGNGLILFDLNHPGKLEKQWFAIDSKEGVITVVGDL 1243 Query: 646 DRESVATHDLKAVAIDGGTP---PQSSTVIVHIKIED-----INDSPPVFESDCLTFYIS 697 D E +H L A D G+P ++ VIV + ED + P F+ + Sbjct: 1244 DYERQRSHRLVVTASDLGSPVSLTSTAAVIVAVSNEDDGEEGTTERAPTFKHRYYEVEVE 1303 Query: 698 ENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS--NSFSLETRQGS------------ 743 EN + + + D + + V YSI + FS++ R GS Sbjct: 1304 ENVEVPVLVARLELADDSDVRDEHVRYSIVADETKARQLFSIDPRNGSLYLTTGVDREVN 1363 Query: 744 DKAELVTMVD---LDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKD-FQI 799 D+ E VD + P Y +V + N+ RV + V DVNDNAP K + Sbjct: 1364 DRYEAKVRVDRVKIGRGMPVMIYPVVGERLNGLAPNEARVVVRVKDVNDNAPRFKSRGRP 1423 Query: 800 IFNNYKDCFPVG-PFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 I G +V A D D +++Y+IL +A ++ +G + Sbjct: 1424 ILAAVPTTAHYGYEVVKVEAEDPDEGANAEIRYQILGREDAPRFAIDPLSGQVRSVASFG 1483 Query: 857 TNVPKLATMEVSVTD 871 + ++ +V TD Sbjct: 1484 RDAGRVFGFDVKATD 1498 Score = 166 bits (403), Expect = 9e-39 Identities = 186/722 (25%), Positives = 313/722 (43%), Gaps = 69/722 (9%) Query: 112 RYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVI 171 ++ V+ +D+ V+ LS T V + D ND+ PQF + Y V+VDE ++ + Sbjct: 86 KFRVVCDYSDEKFIVTSHLSVT----VYVEDINDHAPQFVDAPYHVTVDE-LTPVGVTIF 140 Query: 172 AKIKATDADV--GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVK-TLDYEQ-VRSYRLVI 227 I A D D NS + YAI+ GN + +FS++S +++ +DY+ R + LVI Sbjct: 141 RGIHAVDGDKPNTPNSDVHYAIVKGNEEGKFSLESGHRTALILREPVDYDNGDREFTLVI 200 Query: 228 RAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVP---------IGYSIVR 278 A D G+P+R+ T + I + D +D P+F +++ + E P I +S Sbjct: 201 AATDRGAPARTTNTTVRITVLDNDDLDPKFTRDVYKAKIYEFYPMPEHPIFVRINFS-TP 259 Query: 279 VQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK-----YQ 333 +QA D D ++A + Y + +GN +DP++ +Y +D + + + Sbjct: 260 IQATDRDRDIDAPIRYDIA----SGNERGFFHLDPKNATLYLKRAIDLDAERNLPSNTFT 315 Query: 334 LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393 L + A+ +P RS A F Y + + E+ P G V+ + A D Sbjct: 316 LQIHASQVDNPLRSGVARVEVEVLDLNDNLPEFEVDLYNISIVENLPNGFSVLQVIARDR 375 Query: 394 D--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS----- 446 D E+ + YE+ + G FS+ +++G + LD ++ R + V A + Sbjct: 376 DQGENGQFDYELV--DPSGAFSVDARSGWLTVRDQSVLDRERRDRLRMRVVAVEKRPSVV 433 Query: 447 ---GGRSDTAMVQINIT--DANNYAPVF-ENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 G S ++ V +++T DAN+ P+F Y D+ +GT + V A D D+G Sbjct: 434 APRNGSSSSSSVDVDVTLLDANDNNPIFVPGNLYELVARSDSKVGTVLGQVHAVDDDLGP 493 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560 N + Y L ++ A F ++ TG I+ ++ E + + V A D Sbjct: 494 NGMVRYRLQKPGNSTA---RTPPFAVDEVTGTISVSESPILE--GRHAIFVEAADQPANP 548 Query: 561 LSDTTDVEISVVDV--NDN----EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614 + + VDV +D EP F Y + + VGTSV Q+ DA V N Sbjct: 549 SERRISLAVVTVDVFRSDGPESLEPDFVGAPYEFWVGANVPVGTSVGQIRLNDA-VKTND 607 Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674 I Y+L E F ++ SG I + ++R + +D +A+ D + V +H Sbjct: 608 LI-YDLLHSYEEGVPFAVEERSGTITVVEEIERFDRSIYDFEAIVTDERDLMLITNVSIH 666 Query: 675 IKIEDINDSPPVFESDC----LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD 730 + D ND +F L F+ EN G IG+I + + I Sbjct: 667 --VVDPNDERGIFTRGTTTAPLVFHARENM-AGAYIGQILPQNGTGSATPATRFFIVNQQ 723 Query: 731 DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDN 790 D S+ T G+ L LD E+ R+ Y + + A S +V ++V D ND+ Sbjct: 724 DVPDISI-TEDGA----LYAPKGLDREA-RQNYSITVIAESQRGVGVFQVSVIVLDENDH 777 Query: 791 AP 792 AP Sbjct: 778 AP 779 Score = 150 bits (363), Expect = 6e-34 Identities = 160/601 (26%), Positives = 262/601 (43%), Gaps = 74/601 (12%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ VLD ND+ P FE+ Y S+ E +G +VL + A D+D G+N + +Y ELV Sbjct: 335 EVEVLDLNDNLPEFEVDLYNISIVENLPNGFSVLQVIARDRDQGENGQFDY--ELV---- 388 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR--ASLDREKVARYTVLVKATD-QASPV 126 +P A F +D RSG L R + LDRE+ R + V A + + S V Sbjct: 389 -DPSGA--------------FSVDARSGWLTVRDQSVLDRERRDRLRMRVVAVEKRPSVV 433 Query: 127 SDR----LSSTATIHVNIIDDNDNYPQF-SEKTYTVSVDEDISVTDNPVIAKIKATDADV 181 + R SS+ + V ++D NDN P F Y + D V V+ ++ A D D+ Sbjct: 434 APRNGSSSSSSVDVDVTLLDANDNNPIFVPGNLYELVARSDSKV--GTVLGQVHAVDDDL 491 Query: 182 GANSAIRYAI-IGGNTQMQ---FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237 G N +RY + GN+ + F++D ++G +S+ ++ E R V A +PS Sbjct: 492 GPNGMVRYRLQKPGNSTARTPPFAVDEVTGTISVSESPILEG-RHAIFVEAADQPANPSE 550 Query: 238 SNTTQLLINIRDVNDNAPR-----FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292 + ++ + + P F + ++ V NVP+G S+ +++ DA + +L Sbjct: 551 RRISLAVVTVDVFRSDGPESLEPDFVGAPYEFWVGANVPVGTSVGQIRLNDAVK--TNDL 608 Query: 293 TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352 Y + G +P ++ RSG + +++R ++ Y TD D Sbjct: 609 IYDLLHSYEEG---VPFAVEERSGTITVVEEIERFDRSIYDFEAIVTDERD--LMLITNV 663 Query: 353 XXXXXXXXXXXXXFMPGQYEVEL---AEDEPPGTPVVTLTATD--ADEDNRLHYEITGGN 407 F G L A + G + + + + I Sbjct: 664 SIHVVDPNDERGIFTRGTTTAPLVFHARENMAGAYIGQILPQNGTGSATPATRFFIVNQQ 723 Query: 408 TRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAP 467 SIT G + + LD + + Y +TV A G V + + D N++AP Sbjct: 724 DVPDISITED---GALYAPKGLDREARQNYSITVIAESQRG-VGVFQVSVIVLDENDHAP 779 Query: 468 VFENAPYTASVFEDAPIGTTV---LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524 F + Y + E++P GT V + ++ATD D GIN ++L E S + F Sbjct: 780 EFTSPLYEGRITENSPPGTKVNLSIPITATDKDEGINQNFVFTLHGERS--------ELF 831 Query: 525 VINPQTGAI----TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580 I+P TG + ++ LDRE + Y T+ A+D G L+ + + I+V DVNDN PV Sbjct: 832 RIHPTTGLVYFEGIDDRTLDREARANYSFTIVAKDNG--GLTSESRLRITVTDVNDNSPV 889 Query: 581 F 581 F Sbjct: 890 F 890 Score = 139 bits (337), Expect = 9e-31 Identities = 114/351 (32%), Positives = 173/351 (49%), Gaps = 43/351 (12%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I+V+D NDH P F+ Y V EG G T+ ++A D D G+NA V Y EL T D Sbjct: 1039 RIHVVDVNDHPPSFDKSWYTFDVAEGTYKGYTLGRVRAVDADHGRNANVTY--ELTTRD- 1095 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 V +F + G + LDRE V + +LV A D P R Sbjct: 1096 ----------DSGVGNVSRIFEVGPGEGVIRVTGVLDRETVPVHRLLVTARDNGVP---R 1142 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED--------ISVTDN-PV---IAKIKAT 177 LSST + VN++D NDN P F + + DE+ SV +N PV + K++A Sbjct: 1143 LSSTVEVEVNVLDVNDNPPVFHDYD-EIEKDENGDPLPVYHASVLENSPVGSRVIKVRAD 1201 Query: 178 DADV--GANSAIRYAI-IGGNTQMQ-FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233 D D N I + + G + Q F+IDS G +++V LDYE+ RS+RLV+ A D G Sbjct: 1202 DTDFAGNGNGLILFDLNHPGKLEKQWFAIDSKEGVITVVGDLDYERQRSHRLVVTASDLG 1261 Query: 234 SP-SRSNTTQLLINIRDVND-------NAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD 285 SP S ++T +++ + + +D AP F ++ V ENV + + R++ D Sbjct: 1262 SPVSLTSTAAVIVAVSNEDDGEEGTTERAPTFKHRYYEVEVEENVEVPVLVARLELADDS 1321 Query: 286 EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLV 336 + + + Y++ D T L +IDPR+G +Y + +DRE +Y+ V Sbjct: 1322 DVRDEHVRYSIV-ADETKARQL-FSIDPRNGSLYLTTGVDREVNDRYEAKV 1370 Score = 134 bits (323), Expect = 4e-29 Identities = 172/710 (24%), Positives = 283/710 (39%), Gaps = 68/710 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I VLD +D P F Y+A + E + ++ + ++ + D Sbjct: 217 RITVLDNDDLDPKFTRDVYKAKIYEFYPMPEHPIFVR-----------INFSTPIQATDR 265 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRA-SLDREKVA---RYTVLVKATDQAS 124 DA + F +D ++ L L RA LD E+ +T+ + A+ + Sbjct: 266 DRDIDAPIRYDIASGNERGFFHLDPKNATLYLKRAIDLDAERNLPSNTFTLQIHASQVDN 325 Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184 P+ S A + V ++D NDN P+F Y +S+ E++ + + ++ A D D G N Sbjct: 326 PLR---SGVARVEVEVLDLNDNLPEFEVDLYNISIVENLP--NGFSVLQVIARDRDQGEN 380 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIR-----------AQDGG 233 Y ++ + FS+D+ SG +++ ++ R RL +R A G Sbjct: 381 GQFDYELV--DPSGAFSVDARSGWLTVRDQSVLDRERRDRLRMRVVAVEKRPSVVAPRNG 438 Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN-VPIGYSIVRVQAYDADEGVNAEL 292 S S S++ + + + D NDN P F E V+ + +G + +V A D D G N + Sbjct: 439 SSS-SSSVDVDVTLLDANDNNPIFVPGNLYELVARSDSKVGTVLGQVHAVDDDLGPNGMV 497 Query: 293 TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATX 352 Y + + P +D +G + S E ++ + V A D P + Sbjct: 498 RYRLQKPGNSTARTPPFAVDEVTGTISVSESPILE--GRHAIFVEAADQPANPSERRISL 555 Query: 353 XXXXXXXXXXXX------XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG 406 F+ YE + + P GT V + DA + N L Y++ Sbjct: 556 AVVTVDVFRSDGPESLEPDFVGAPYEFWVGANVPVGTSVGQIRLNDAVKTNDLIYDLLHS 615 Query: 407 NTRG-RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNY 465 G F++ ++G ITV + ++ Y TD V I++ D N+ Sbjct: 616 YEEGVPFAVEERSGT--ITVVEEIERFDRSIYDFEAIVTDERDLMLITNVSIHVVDPNDE 673 Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525 +F TA + A + G T S + V D + Sbjct: 674 RGIFTRGTTTAPLVFHARENMAGAYIGQILPQNG-----TGSATPATRFFIVNQQDVPDI 728 Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEPVFKQQ 584 + GA+ K LDRE Y +TV A GV V + V+D ND+ P F Sbjct: 729 SITEDGALYAPKGLDREARQNYSITVIAESQRGV----GVFQVSVIVLDENDHAPEFTSP 784 Query: 585 LYTANIMEDALVGTSVS---QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR- 640 LY I E++ GT V+ + ATD D G+N + L + E F I P +G++ Sbjct: 785 LYEGRITENSPPGTKVNLSIPITATDKDEGINQNFVFTLHGERSE--LFRIHPTTGLVYF 842 Query: 641 ---TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687 ++ LDRE+ A + VA D G S + I + D+ND+ PVF Sbjct: 843 EGIDDRTLDREARANYSFTIVAKDNGGLTSESRL--RITVTDVNDNSPVF 890 >UniRef50_UPI000069FDB0 Cluster: Protocadherin LKC precursor (PC-LKC).; n=3; Xenopus tropicalis|Rep: Protocadherin LKC precursor (PC-LKC). - Xenopus tropicalis Length = 1312 Score = 198 bits (483), Expect = 2e-48 Identities = 226/864 (26%), Positives = 372/864 (43%), Gaps = 97/864 (11%) Query: 13 VLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNP 72 V D ND+ PVF YEAS+RE G+ V ++ A D D V Y+I D + P Sbjct: 116 VEDRNDNDPVFLGIPYEASIREDQPLGSIVFSVSAVDFDDDGRVPVTYSI-----DEIIP 170 Query: 73 EDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL-- 130 D ++F I +L EK Y + + ATD+ + Sbjct: 171 NDLQS---------NNLFYILLNGSIILNDTLNYNEKSIFYQMTINATDKGGLFHNHFMY 221 Query: 131 -SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S+ A + + +ID D PQF Y+VS++E+I++ I ++ A D D G N I+Y Sbjct: 222 RSTLAYVSLKVIDLPDLDPQFINAPYSVSIEENIAL--GTTIFRVTAIDGDRGINDEIQY 279 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV----RSYRLVIRAQDG----GSPSRSNTT 241 +I + F I+S SG++ + +D E + L + AQ+ + ++TT Sbjct: 280 SIQDSSRHGLFDINSKSGEIFVTAKIDREALVQDGEQVLLTVMAQEKNLNVNAEKATSTT 339 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT--MTDK 299 + + + D+NDN P FY + P + ++ + + A+L T DK Sbjct: 340 TVTVRVLDINDNKPNFYNCEIDDCDFSAAPTLSFLGEIEEHSSIRVPVAKLKITGHDPDK 399 Query: 300 DYTGNVDLPI--------TIDP----RSGWVYT----SGQLDRETQAKYQL-LVTATDGG 342 D GN +L + T+ P +G + S +D E + ++ + A D G Sbjct: 400 DKNGNFNLYLRGKDQDCFTVSPARVQNTGLIQVLVKDSVAIDYEKVHQMEVEQIVANDTG 459 Query: 343 DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLH 400 + AT F Y +E+ E+ P GT + T+TATD D E ++ Sbjct: 460 LQDCCSYATVTIDIIDINDHTPEFSQDTYYLEVMENCPDGTQIGTITATDLDSGELGKIT 519 Query: 401 YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT 460 Y++ + R F + S +G LD ++ Y T+ A D + TA+++I I Sbjct: 520 YQLLPESIRQIFHVDSDSGEITAVNGNLLDRERRSLYYATLQAADGLNATGTALLEITIL 579 Query: 461 DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV--GINAQITYSLSSEISNEAVA 518 D N+ P A + ++F + + + A D+D N++I + L + + Sbjct: 580 DENDEIP---TAIGSYNIFVNENTDDVRIQIEAFDADEPNTNNSRIEFELLPSVLS---- 632 Query: 519 HHDQQFVINPQTGAITTNKLLDRETMSG-----YLLTVTARDGGVPSLSDTTDVEISVVD 573 F +N TG IT+ LDRE + +LTV D GVPSLS +V I+V D Sbjct: 633 ---SNFSVNVTTGLITSIGPLDREAIDEKDNGCIVLTVKLYDLGVPSLSSEVNVTINVED 689 Query: 574 VNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGSFVI 632 +NDN PVF + +Y + ++ + V + +D D LN R+ + + G+F+I Sbjct: 690 LNDNVPVFSKTVYDF-FVNESTIAAQVGILLVSDQDQTELNNRVSFRI--SQGGSGNFII 746 Query: 633 ---DPASGV------IRTNKALDRESVATHDLKAVAIDGGT--PPQSSTVIVHIKIEDIN 681 SG+ + + LD E+ + L A D G ++T +++ D+N Sbjct: 747 RNQKVESGLYNGILSLDPDVMLDYETQKNYTLIIEAQDNGLHGVSHTATATASVQVLDLN 806 Query: 682 DSPPVFESDCL-TFYISENSPIG-TTIGEIRAHDPDE----GPNAVVHYSIKGGDDSNSF 735 D PP + L ++ EN +G + ++AHDPD A+ K G+D + Sbjct: 807 DEPPYVDPSSLNNLFLLENRTVGLELLTTLKAHDPDTIHELEFQALSLQCFKNGNDIGNI 866 Query: 736 SLETRQGSDKAEL-VTMVD-LDYE-------SPRKKYELVIRAASPPLWNDVRVEILVTD 786 + + EL V + +DYE R + +L + +RV+IL D Sbjct: 867 CYDWIWLAPNGELFVNDTEVVDYELCDVMVMMLRVEDKLTLIGDRYSKNESLRVDIL--D 924 Query: 787 VNDNAPVMKDFQIIFNNYKDCFPV 810 VNDNAP D +F D P+ Sbjct: 925 VNDNAPEFLDVDEVFVVVPDVAPI 948 Score = 184 bits (447), Expect = 4e-44 Identities = 207/760 (27%), Positives = 331/760 (43%), Gaps = 84/760 (11%) Query: 138 VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI---IGG 194 V + D NDN P F Y S+ ED + ++ + A D D + Y+I I Sbjct: 114 VIVEDRNDNDPVFLGIPYEASIREDQPL--GSIVFSVSAVDFDDDGRVPVTYSIDEIIPN 171 Query: 195 NTQMQ--FSIDSLSGDVSLVKTLDY-EQVRSYRLVIRAQDGGS------PSRSNTTQLLI 245 + Q F I L+G + L TL+Y E+ Y++ I A D G RS + + Sbjct: 172 DLQSNNLFYI-LLNGSIILNDTLNYNEKSIFYQMTINATDKGGLFHNHFMYRSTLAYVSL 230 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 + D+ D P+F + + S+ EN+ +G +I RV A D D G+N E+ Y++ D G Sbjct: 231 KVIDLPDLDPQFINAPYSVSIEENIALGTTIFRVTAIDGDRGINDEIQYSIQDSSRHGLF 290 Query: 306 DLPITIDPRSGWVYTSGQLDRE--TQAKYQLLVT--ATDGGDPPRSATATXXXXXXXXXX 361 D I+ +SG ++ + ++DRE Q Q+L+T A + + AT Sbjct: 291 D----INSKSGEIFVTAKIDREALVQDGEQVLLTVMAQEKNLNVNAEKATSTTTVTVRVL 346 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVT-------------------LTATDADEDNRLHYE 402 P Y E+ + + P ++ +T D D+D ++ Sbjct: 347 DINDNKPNFYNCEIDDCDFSAAPTLSFLGEIEEHSSIRVPVAKLKITGHDPDKDKNGNFN 406 Query: 403 I-TGGNTRGRFSITSQ--NGRGLITV----AQPLDF-KQERRYVLTVSATDSGGRS--DT 452 + G + F+++ GLI V + +D+ K + V + A D+G + Sbjct: 407 LYLRGKDQDCFTVSPARVQNTGLIQVLVKDSVAIDYEKVHQMEVEQIVANDTGLQDCCSY 466 Query: 453 AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512 A V I+I D N++ P F Y V E+ P GT + ++ATD D G +ITY L E Sbjct: 467 ATVTIDIIDINDHTPEFSQDTYYLEVMENCPDGTQIGTITATDLDSGELGKITYQLLPE- 525 Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572 S + H D + + A+ N LLDRE S Y T+ A DG + + T +EI+++ Sbjct: 526 SIRQIFHVDSD---SGEITAVNGN-LLDRERRSLYYATLQAADG--LNATGTALLEITIL 579 Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV--GLNGRIHYELDPKDREEGSF 630 D ND P + + NI + Q+ A DAD N RI +EL P +F Sbjct: 580 DENDEIPT---AIGSYNIFVNENTDDVRIQIEAFDADEPNTNNSRIEFELLPSVL-SSNF 635 Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAI-----DGGTPPQSSTVIVHIKIEDINDSPP 685 ++ +G+I + LDRE++ D + + D G P SS V V I +ED+ND+ P Sbjct: 636 SVNVTTGLITSIGPLDREAIDEKDNGCIVLTVKLYDLGVPSLSSEVNVTINVEDLNDNVP 695 Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGP-NAVVHYSIKGGDDSNSFSLETRQGSD 744 VF F+++E S I +G + D D+ N V + I G N + S Sbjct: 696 VFSKTVYDFFVNE-STIAAQVGILLVSDQDQTELNNRVSFRISQGGSGNFIIRNQKVESG 754 Query: 745 KAELVTMVD----LDYESPRKKYELVIRAASPPLWN-----DVRVEILVTDVNDNAPVMK 795 + +D LDYE+ +K Y L+I A L + V D+ND P + Sbjct: 755 LYNGILSLDPDVMLDYET-QKNYTLIIEAQDNGLHGVSHTATATASVQVLDLNDEPPYVD 813 Query: 796 DFQI--IFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILS 833 + +F + + A+D D +L+++ LS Sbjct: 814 PSSLNNLFLLENRTVGLELLTTLKAHDPDTIHELEFQALS 853 Score = 156 bits (378), Expect = 9e-36 Identities = 178/652 (27%), Positives = 283/652 (43%), Gaps = 81/652 (12%) Query: 252 DNAPRFYTSLFQESVSENVP-IGYSIVRVQAYDADEGVNAELTYTMTDKD-YTGNVDLPI 309 + AP F +++ + E+ P +G + + A DAD N LTY+M +D Y NV+L Sbjct: 22 NTAPEFASNMTSAFIPEDTPLVGKCVFWIVARDAD---NDPLTYSMEGQDSYYFNVNL-- 76 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPG 369 +G V + LD E +Y + + P F+ Sbjct: 77 ----MTGEVQLALPLDYEVGFQYLVQLLRNI---PALQVIRQFPVIVEDRNDNDPVFLGI 129 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDNRLH--YEITG--GNTRGRFSITSQNGRGLITV 425 YE + ED+P G+ V +++A D D+D R+ Y I N ++ G I + Sbjct: 130 PYEASIREDQPLGSIVFSVSAVDFDDDGRVPVTYSIDEIIPNDLQSNNLFYILLNGSIIL 189 Query: 426 AQPLDFKQERR-YVLTVSATDSGG--------RSDTAMVQINITDANNYAPVFENAPYTA 476 L++ ++ Y +T++ATD GG RS A V + + D + P F NAPY+ Sbjct: 190 NDTLNYNEKSIFYQMTINATDKGGLFHNHFMYRSTLAYVSLKVIDLPDLDPQFINAPYSV 249 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 S+ E+ +GTT+ V+A D D GIN +I YS+ + H F IN ++G I Sbjct: 250 SIEENIALGTTIFRVTAIDGDRGINDEIQYSIQDS------SRHG-LFDINSKSGEIFVT 302 Query: 537 KLLDRETM----SGYLLTVTARDGGV----PSLSDTTDVEISVVDVNDNEPVF------- 581 +DRE + LLTV A++ + + TT V + V+D+NDN+P F Sbjct: 303 AKIDREALVQDGEQVLLTVMAQEKNLNVNAEKATSTTTVTVRVLDINDNKPNFYNCEIDD 362 Query: 582 ------KQQLYTANIMEDALVGTSVSQVGAT--DADVGLNGRIHYELDPKDREEGSFVID 633 + I E + + V+++ T D D NG + L KD++ F + Sbjct: 363 CDFSAAPTLSFLGEIEEHSSIRVPVAKLKITGHDPDKDKNGNFNLYLRGKDQD--CFTVS 420 Query: 634 PA----SGVI----RTNKALDRESVATHDL-KAVAIDGGTPPQSSTVIVHIKIEDINDSP 684 PA +G+I + + A+D E V ++ + VA D G S V I I DIND Sbjct: 421 PARVQNTGLIQVLVKDSVAIDYEKVHQMEVEQIVANDTGLQDCCSYATVTIDIIDINDHT 480 Query: 685 PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD 744 P F D + EN P GT IG I A D D G + Y + F +++ G Sbjct: 481 PEFSQDTYYLEVMENCPDGTQIGTITATDLDSGELGKITYQLLPESIRQIFHVDSDSGEI 540 Query: 745 KAELVTMVDLDYESPRKKYELVIRAASP-PLWNDVRVEILVTDVNDNAP-VMKDFQIIFN 802 A ++D R Y ++AA +EI + D ND P + + I N Sbjct: 541 TAVNGNLLD---RERRSLYYATLQAADGLNATGTALLEITILDENDEIPTAIGSYNIFVN 597 Query: 803 NYKDCFPVGPFGRVPAYDADV----TDKLQYRILSGNNANLILLNETTGSMT 850 D + ++ A+DAD ++++ +L ++ +N TTG +T Sbjct: 598 ENTDDVRI----QIEAFDADEPNTNNSRIEFELLPSVLSSNFSVNVTTGLIT 645 Score = 150 bits (364), Expect = 5e-34 Identities = 186/758 (24%), Positives = 312/758 (41%), Gaps = 72/758 (9%) Query: 141 IDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQF 200 + + P+F+ + + ED + V I A DAD N + Y++ G ++ F Sbjct: 18 VSSQNTAPEFASNMTSAFIPEDTPLVGKCVFW-IVARDAD---NDPLTYSMEGQDSYY-F 72 Query: 201 SIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260 +++ ++G+V L LDYE Y + + P+ Q + + D NDN P F Sbjct: 73 NVNLMTGEVQLALPLDYEVGFQYLVQLLRN---IPALQVIRQFPVIVEDRNDNDPVFLGI 129 Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD---KDYTGNVDLPITIDPRSGW 317 ++ S+ E+ P+G + V A D D+ +TY++ + D N I ++ G Sbjct: 130 PYEASIREDQPLGSIVFSVSAVDFDDDGRVPVTYSIDEIIPNDLQSNNLFYILLN---GS 186 Query: 318 VYTSGQLD-RETQAKYQLLVTATDGGD------PPRSATATXXXXXXXXXXXXXXFMPGQ 370 + + L+ E YQ+ + ATD G RS A F+ Sbjct: 187 IILNDTLNYNEKSIFYQMTINATDKGGLFHNHFMYRSTLAYVSLKVIDLPDLDPQFINAP 246 Query: 371 YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLIT--VA 426 Y V + E+ GT + +TA D D ++ + Y I + G F I S++G +T + Sbjct: 247 YSVSIEENIALGTTIFRVTAIDGDRGINDEIQYSIQDSSRHGLFDINSKSGEIFVTAKID 306 Query: 427 QPLDFKQERRYVLTVSATDSG------GRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 + + + +LTV A + + T V + + D N+ P F N F Sbjct: 307 REALVQDGEQVLLTVMAQEKNLNVNAEKATSTTTVTVRVLDINDNKPNFYNCEIDDCDFS 366 Query: 481 DAPIGTTVLVVSATDS------DVGINAQITYSLSSEISNEAVAHHDQQ-FVINP----Q 529 AP + + + S + I + N + DQ F ++P Sbjct: 367 AAPTLSFLGEIEEHSSIRVPVAKLKITGHDPDKDKNGNFNLYLRGKDQDCFTVSPARVQN 426 Query: 530 TGAITT----NKLLDRETMSGYLLT-VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584 TG I + +D E + + + A D G+ V I ++D+ND+ P F Q Sbjct: 427 TGLIQVLVKDSVAIDYEKVHQMEVEQIVANDTGLQDCCSYATVTIDIIDINDHTPEFSQD 486 Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR--TN 642 Y +ME+ GT + + ATD D G G+I Y+L P+ + F +D SG I Sbjct: 487 TYYLEVMENCPDGTQIGTITATDLDSGELGKITYQLLPESIRQ-IFHVDSDSGEITAVNG 545 Query: 643 KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 LDRE + + A DG + T ++ I I D ND P +++EN+ Sbjct: 546 NLLDRERRSLYYATLQAADGLN--ATGTALLEITILDENDEIPT-AIGSYNIFVNENTD- 601 Query: 703 GTTIGEIRAHDPDE--GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV-DLDYESP 759 I +I A D DE N+ + + + S++FS+ G L+T + LD E+ Sbjct: 602 DVRI-QIEAFDADEPNTNNSRIEFELLPSVLSSNFSVNVTTG-----LITSIGPLDREAI 655 Query: 760 RKK----YELVIR---AASPPLWNDVRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPV 810 +K L ++ P L ++V V I V D+NDN PV + N V Sbjct: 656 DEKDNGCIVLTVKLYDLGVPSLSSEVNVTINVEDLNDNVPVFSKTVYDFFVNESTIAAQV 715 Query: 811 GPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGS 848 G ++ +++ +RI G + N I+ N+ S Sbjct: 716 GILLVSDQDQTELNNRVSFRISQGGSGNFIIRNQKVES 753 Score = 147 bits (356), Expect = 4e-33 Identities = 207/839 (24%), Positives = 344/839 (41%), Gaps = 104/839 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V+D D P F Y S+ E + GTT+ + A D D G N E++Y+I+ Sbjct: 230 LKVIDLPDLDPQFINAPYSVSIEENIALGTTIFRVTAIDGDRGINDEIQYSIQ------- 282 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR----YTVLVKATDQASPV 126 D+ +F I+ +SG + A +DRE + + + V A ++ V Sbjct: 283 ---DSSR---------HGLFDINSKSGEIFVTAKIDREALVQDGEQVLLTVMAQEKNLNV 330 Query: 127 S-DRLSSTATIHVNIIDDNDNYPQFSE-------------KTYTVSVDEDISVTDNPVIA 172 + ++ +ST T+ V ++D NDN P F ++ ++E S+ Sbjct: 331 NAEKATSTTTVTVRVLDINDNKPNFYNCEIDDCDFSAAPTLSFLGEIEEHSSIRVPVAKL 390 Query: 173 KIKATDADVGANSAIRYAIIGGNTQMQFSIDSL----SGDVS-LVK---TLDYEQVRSYR 224 KI D D N + G Q F++ +G + LVK +DYE+V Sbjct: 391 KITGHDPDKDKNGNFNL-YLRGKDQDCFTVSPARVQNTGLIQVLVKDSVAIDYEKVHQME 449 Query: 225 LV-IRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYD 283 + I A D G + + I+I D+ND+ P F + V EN P G I + A D Sbjct: 450 VEQIVANDTGLQDCCSYATVTIDIIDINDHTPEFSQDTYYLEVMENCPDGTQIGTITATD 509 Query: 284 ADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV--YTSGQLDRETQAKYQLLVTATDG 341 D G ++TY + + ++ +D SG + LDRE ++ Y + A DG Sbjct: 510 LDSGELGKITYQLLPE----SIRQIFHVDSDSGEITAVNGNLLDRERRSLYYATLQAADG 565 Query: 342 GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN---- 397 + +A G Y + + E+ + + A DADE N Sbjct: 566 LNATGTALLEITILDENDEIPTAI---GSYNIFVNENTDDVR--IQIEAFDADEPNTNNS 620 Query: 398 RLHYEITGGNTRGRFSITSQNGRGLITVAQPL-----DFKQERRYVLTVSATDSG--GRS 450 R+ +E+ FS+ GLIT PL D K VLTV D G S Sbjct: 621 RIEFELLPSVLSSNFSVNVTT--GLITSIGPLDREAIDEKDNGCIVLTVKLYDLGVPSLS 678 Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYSLS 509 V IN+ D N+ PVF Y V ++ I V ++ +D D +N ++++ +S Sbjct: 679 SEVNVTINVEDLNDNVPVFSKTVYDFFV-NESTIAAQVGILLVSDQDQTELNNRVSFRIS 737 Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNK--LLDRETMSGYLLTVTARDGGVPSLSD--TT 565 S + +Q+ G ++ + +LD ET Y L + A+D G+ +S T Sbjct: 738 QGGSGNFII-RNQKVESGLYNGILSLDPDVMLDYETQKNYTLIIEAQDNGLHGVSHTATA 796 Query: 566 DVEISVVDVNDNEP-VFKQQLYTANIMEDALVGTS-VSQVGATDADV--GLNGR-IHYEL 620 + V+D+ND P V L ++E+ VG ++ + A D D L + + + Sbjct: 797 TASVQVLDLNDEPPYVDPSSLNNLFLLENRTVGLELLTTLKAHDPDTIHELEFQALSLQC 856 Query: 621 DPKDREEGSFVID----PASGVIRTN--KALDRESVATHDLKAVAIDGGT---PPQSSTV 671 + G+ D +G + N + +D E + D T S Sbjct: 857 FKNGNDIGNICYDWIWLAPNGELFVNDTEVVDYELCDVMVMMLRVEDKLTLIGDRYSKNE 916 Query: 672 IVHIKIEDINDSPPVF-ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD 730 + + I D+ND+ P F + D + + + +PI + ++A D D G NAV+ +SI Sbjct: 917 SLRVDILDVNDNAPEFLDVDEVFVVVPDVAPIDYQVALVKATDKDSGLNAVLKFSIA--- 973 Query: 731 DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTD 786 S+E G L+ + + S ++ Y+ IR AS L + RV ++ D Sbjct: 974 -----SVEFISGDSTRPLLNIFTIVTTSEKEIYQGSIRVASSLDATLKGNYRVTVIAED 1027 Score = 142 bits (344), Expect = 1e-31 Identities = 162/606 (26%), Positives = 267/606 (44%), Gaps = 74/606 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+++D NDH+P F Y V E GT + T+ ATD D G+ ++ Y L Sbjct: 471 IDIIDINDHTPEFSQDTYYLEVMENCPDGTQIGTITATDLDSGELGKITYQ--------L 522 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGAL--LTRASLDREKVARYTVLVKATDQASPVSD 128 PE ++ +F +D SG + + LDRE+ + Y ++A D + Sbjct: 523 LPES-----------IRQIFHVDSDSGEITAVNGNLLDRERRSLYYATLQAADGLNA--- 568 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA--NSA 186 + TA + + I+D+ND P + +Y + V+E+ TD+ V +I+A DAD NS Sbjct: 569 --TGTALLEITILDENDEIPT-AIGSYNIFVNEN---TDD-VRIQIEAFDADEPNTNNSR 621 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR-----LVIRAQDGGSPSRSNTT 241 I + ++ FS++ +G ++ + LD E + L ++ D G PS S+ Sbjct: 622 IEFELLPSVLSSNFSVNVTTGLITSIGPLDREAIDEKDNGCIVLTVKLYDLGVPSLSSEV 681 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSEN-VPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 + IN+ D+NDN P F +++ V+E+ + I+ V D E +N +++ ++ Sbjct: 682 NVTINVEDLNDNVPVFSKTVYDFFVNESTIAAQVGILLVSDQDQTE-LNNRVSFRISQGG 740 Query: 301 YTGNVDL---PITIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGG--DPPRSATATXX 353 +GN + + +G + LD ETQ Y L++ A D G +ATAT Sbjct: 741 -SGNFIIRNQKVESGLYNGILSLDPDVMLDYETQKNYTLIIEAQDNGLHGVSHTATATAS 799 Query: 354 XXXXXXXXXXXXFMPGQYE-VELAEDEPPGTPVVT-LTATDADEDNRLHYE------ITG 405 P + L E+ G ++T L A D D + L ++ Sbjct: 800 VQVLDLNDEPPYVDPSSLNNLFLLENRTVGLELLTTLKAHDPDTIHELEFQALSLQCFKN 859 Query: 406 GNTRGRFSIT----SQNGRGLITVAQPLDFKQERRYVLTVSATDS----GGR-SDTAMVQ 456 GN G + NG + + +D++ V+ + D G R S ++ Sbjct: 860 GNDIGNICYDWIWLAPNGELFVNDTEVVDYELCDVMVMMLRVEDKLTLIGDRYSKNESLR 919 Query: 457 INITDANNYAPVFENAPYTASVFED-APIGTTVLVVSATDSDVGINAQITYSLSSE--IS 513 ++I D N+ AP F + V D API V +V ATD D G+NA + +S++S IS Sbjct: 920 VDILDVNDNAPEFLDVDEVFVVVPDVAPIDYQVALVKATDKDSGLNAVLKFSIASVEFIS 979 Query: 514 NEAVAHHDQQFVINPQT------GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567 ++ F I + G+I LD Y +TV A D G PSL+ T + Sbjct: 980 GDSTRPLLNIFTIVTTSEKEIYQGSIRVASSLDATLKGNYRVTVIAEDSGNPSLTATRVL 1039 Query: 568 EISVVD 573 +I VD Sbjct: 1040 DIFAVD 1045 Score = 134 bits (325), Expect = 3e-29 Identities = 146/574 (25%), Positives = 259/574 (45%), Gaps = 53/574 (9%) Query: 375 LAEDEP-PGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ 433 + ED P G V + A DAD D L Y + G ++ F++ G + +A PLD++ Sbjct: 36 IPEDTPLVGKCVFWIVARDADNDP-LTYSMEGQDSY-YFNVNLMTGE--VQLALPLDYEV 91 Query: 434 ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 +Y++ + + + + D N+ PVF PY AS+ ED P+G+ V VSA Sbjct: 92 GFQYLVQL-LRNIPALQVIRQFPVIVEDRNDNDPVFLGIPYEASIREDQPLGSIVFSVSA 150 Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD-RETMSGYLLTVT 552 D D +TYS+ I N+ +++ ++N G+I N L+ E Y +T+ Sbjct: 151 VDFDDDGRVPVTYSIDEIIPNDLQSNNLFYILLN---GSIILNDTLNYNEKSIFYQMTIN 207 Query: 553 ARD-GGV-----PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 A D GG+ S V + V+D+ D +P F Y+ +I E+ +GT++ +V A Sbjct: 208 ATDKGGLFHNHFMYRSTLAYVSLKVIDLPDLDPQFINAPYSVSIEENIALGTTIFRVTAI 267 Query: 607 DADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD----LKAVA--- 659 D D G+N I Y + R G F I+ SG I +DRE++ L +A Sbjct: 268 DGDRGINDEIQYSIQDSSR-HGLFDINSKSGEIFVTAKIDREALVQDGEQVLLTVMAQEK 326 Query: 660 -IDGGTPPQSSTVIVHIKIEDINDSPPVFES----DC-------LTFY--ISENSPIGTT 705 ++ +ST V +++ DIND+ P F + DC L+F I E+S I Sbjct: 327 NLNVNAEKATSTTTVTVRVLDINDNKPNFYNCEIDDCDFSAAPTLSFLGEIEEHSSIRVP 386 Query: 706 IGEIR--AHDPDEGPNAVVHYSIKGGD-DSNSFSLETRQGSDKAELVT--MVDLDYESPR 760 + +++ HDPD+ N + ++G D D + S Q + +++ V +DYE Sbjct: 387 VAKLKITGHDPDKDKNGNFNLYLRGKDQDCFTVSPARVQNTGLIQVLVKDSVAIDYEKVH 446 Query: 761 K-KYELVIR--AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVP 817 + + E ++ + V I + D+ND+ P ++C G + Sbjct: 447 QMEVEQIVANDTGLQDCCSYATVTIDIIDINDHTPEFSQDTYYLEVMENCPDGTQIGTIT 506 Query: 818 AYDADVTD--KLQYRILSGNNANLILLNETTGSMTL--SPQLNTNVPKLATMEVSVTDGV 873 A D D + K+ Y++L + + ++ +G +T L+ L + DG+ Sbjct: 507 ATDLDSGELGKITYQLLPESIRQIFHVDSDSGEITAVNGNLLDRERRSLYYATLQAADGL 566 Query: 874 NEI-KAMMQLSVRLITEEM--LLNSITVRLNDMT 904 N A++++++ +E+ + S + +N+ T Sbjct: 567 NATGTALLEITILDENDEIPTAIGSYNIFVNENT 600 Score = 45.2 bits (102), Expect = 0.026 Identities = 34/139 (24%), Positives = 69/139 (49%), Gaps = 14/139 (10%) Query: 10 QINVLDCNDHSPVF-EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI---ELV 65 ++++LD ND++P F ++ + V + A V +KATD+D G NA ++++I E + Sbjct: 919 RVDILDVNDNAPEFLDVDEVFVVVPDVAPIDYQVALVKATDKDSGLNAVLKFSIASVEFI 978 Query: 66 TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125 + D+ P +++++ G++ +SLD Y V V A D +P Sbjct: 979 SGDSTRP--LLNIFTIVTTSEKEIYQ-----GSIRVASSLDATLKGNYRVTVIAEDSGNP 1031 Query: 126 VSDRLSSTATIHVNIIDDN 144 L++T + + +D++ Sbjct: 1032 ---SLTATRVLDIFAVDES 1047 >UniRef50_UPI0000F2B47D Cluster: PREDICTED: similar to matrix metalloproteinase 13; n=8; Theria|Rep: PREDICTED: similar to matrix metalloproteinase 13 - Monodelphis domestica Length = 860 Score = 196 bits (479), Expect = 5e-48 Identities = 177/612 (28%), Positives = 263/612 (42%), Gaps = 29/612 (4%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 FR+ ++G L + LDRE++ + V + + V + D NDN P Sbjct: 87 FRLHRKTGDLFVKEKLDREELCGKAD--PCVLRFEIVLEEPLQSFRAEVRVFDINDNAPM 144 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG---NTQMQF-SIDSL 205 F + + E + + A D DVG N Y + + +F S Sbjct: 145 FPNHGPVLKIPESTPLGSRFPLQS--AQDLDVGLNGLQNYTLSANAYFHLHTRFRSHGPK 202 Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265 ++ L+K LD E+ L + A DGGSP++S T Q+LI + DVNDN P+F +++ Sbjct: 203 YAELVLIKPLDREEQPQVCLTLTAVDGGSPAKSGTAQILIVVLDVNDNVPQFSRLVYRAQ 262 Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325 + EN P G + V A D DEG N E+ Y++ + I+ +G + G +D Sbjct: 263 ILENSPNGSLVTSVSATDLDEGTNREIVYSLAQN--PEGILQTFHINFENGEIRLRGPVD 320 Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 E Y + V A DGG SA + + + ED P T V Sbjct: 321 FEAIENYDIDVQAIDGGG--LSAHSKVLVEVMDVNDNAPDVLITSISNRIPEDSPLNT-V 377 Query: 386 VTLTATDADEDNRLHYEIT---GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVS 442 V L D D R+ +IT G+ T +N L+T LD ++ Y LT+ Sbjct: 378 VALFGV-RDRDIRVGGKITCFIQGDLPFTIKQTFRNSYSLVT-GGTLDREKVAGYNLTIV 435 Query: 443 ATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 A DSG S ++++ I+D N+ PVF+ A YT +V E+ + V A D D Sbjct: 436 AMDSGTPRLSSETIIEVVISDINDNPPVFKEASYTMTVRENNSPAVFIGKVQAEDLDSEE 495 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560 NAQITYSL S + IN G + + +D E + + V A +GG Sbjct: 496 NAQITYSLLPPESGDLSVF--SYISINSNNGKLYALRSMDYEAIQAFQFVVKAVNGGPLP 553 Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTAN------IMEDALVGTSVSQVGATDADVGLNG 614 LS V + V+DVNDN P+ L + + A VG V++V A D D G N Sbjct: 554 LSSQIIVRVVVLDVNDNLPMILYPLQNSTSPCNDLVPRVAEVGYLVTKVVAVDGDSGQNS 613 Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674 + YEL K + G F + SG IRT + + + D G P S+T ++ Sbjct: 614 WLSYEL-LKATDLGLFSVGRQSGEIRTLRLISERDSMKQKMVIAVRDHGQPSLSTTATLN 672 Query: 675 IKIEDINDSPPV 686 I + D P V Sbjct: 673 ILLVDGFSDPYV 684 Score = 191 bits (466), Expect = 2e-46 Identities = 160/534 (29%), Positives = 258/534 (48%), Gaps = 41/534 (7%) Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480 + + +PLD +++ + LT++A D G +S TA + I + D N+ P F Y A + E Sbjct: 206 LVLIKPLDREEQPQVCLTLTAVDGGSPAKSGTAQILIVVLDVNDNVPQFSRLVYRAQILE 265 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 ++P G+ V VSATD D G N +I YSL+ + E + Q F IN + G I +D Sbjct: 266 NSPNGSLVTSVSATDLDEGTNREIVYSLAQ--NPEGIL---QTFHINFENGEIRLRGPVD 320 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 E + Y + V A DGG LS + V + V+DVNDN P + I ED+ + T V Sbjct: 321 FEAIENYDIDVQAIDGG--GLSAHSKVLVEVMDVNDNAPDVLITSISNRIPEDSPLNTVV 378 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA---SGVIRTNKALDRESVATHDLKA 657 + G D D+ + G+I + + + F I S + T LDRE VA ++L Sbjct: 379 ALFGVRDRDIRVGGKITCFI----QGDLPFTIKQTFRNSYSLVTGGTLDREKVAGYNLTI 434 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 VA+D GTP SS I+ + I DIND+PPVF+ T + EN+ IG+++A D D Sbjct: 435 VAMDSGTPRLSSETIIEVVISDINDNPPVFKEASYTMTVRENNSPAVFIGKVQAEDLDSE 494 Query: 718 PNAVVHYSI--KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP--- 772 NA + YS+ D + FS S+ +L + +DYE+ + ++ V++A + Sbjct: 495 ENAQITYSLLPPESGDLSVFSY-ISINSNNGKLYALRSMDYEA-IQAFQFVVKAVNGGPL 552 Query: 773 PLWNDVRVEILVTDVNDNAP-VMKDFQIIFNNYKDCFP-VGPFG----RVPAYDADVTDK 826 PL + + V ++V DVNDN P ++ Q + D P V G +V A D D Sbjct: 553 PLSSQIIVRVVVLDVNDNLPMILYPLQNSTSPCNDLVPRVAEVGYLVTKVVAVDGDSGQN 612 Query: 827 --LQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLS 883 L Y +L + L + +G + ++ M ++V D G + L+ Sbjct: 613 SWLSYELLKATDLGLFSVGRQSGEIRTLRLISERDSMKQKMVIAVRDHGQPSLSTTATLN 672 Query: 884 VRLITEEMLLNSITVRLNDMT-AEQFLSPLLGFFIDGLAAIIPCPKENIYIFSV 936 + L+ + V+L D + E+ +P + + LA + ++++FSV Sbjct: 673 ILLVDG---FSDPYVQLRDHSKRERKTNPSTKYLVISLAVL-----SSLFLFSV 718 Score = 141 bits (341), Expect = 3e-31 Identities = 128/462 (27%), Positives = 205/462 (44%), Gaps = 43/462 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I VLD ND+ P F Y A + E + +G+ V ++ ATD D G N E+ Y++ Sbjct: 242 IVVLDVNDNVPQFSRLVYRAQILENSPNGSLVTSVSATDLDEGTNREIVYSL------AQ 295 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 NPE + F I+ +G + R +D E + Y + V+A D L Sbjct: 296 NPE-----------GILQTFHINFENGEIRLRGPVDFEAIENYDIDVQAIDGGG-----L 339 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S+ + + V ++D NDN P + + + ED + N V+A D D+ I Sbjct: 340 SAHSKVLVEVMDVNDNAPDVLITSISNRIPEDSPL--NTVVALFGVRDRDIRVGGKITCF 397 Query: 191 IIGGNTQMQFSI-DSLSGDVSLVK--TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 I G + F+I + SLV TLD E+V Y L I A D G+P S+ T + + I Sbjct: 398 IQG---DLPFTIKQTFRNSYSLVTGGTLDREKVAGYNLTIVAMDSGTPRLSSETIIEVVI 454 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 D+NDN P F + + +V EN I +VQA D D NA++TY++ + +G++ + Sbjct: 455 SDINDNPPVFKEASYTMTVRENNSPAVFIGKVQAEDLDSEENAQITYSLLPPE-SGDLSV 513 Query: 308 --PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 I+I+ +G +Y +D E +Q +V A +GG P S+ Sbjct: 514 FSYISINSNNGKLYALRSMDYEAIQAFQFVVKAVNGGPLPLSSQIIVRVVVLDVNDNLPM 573 Query: 366 FM-PGQYEVELAEDEPP-----GTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQ 417 + P Q D P G V + A D D +++ L YE+ G FS+ Q Sbjct: 574 ILYPLQNSTSPCNDLVPRVAEVGYLVTKVVAVDGDSGQNSWLSYELLKATDLGLFSVGRQ 633 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINI 459 +G I + + + + + ++ D G S + +NI Sbjct: 634 SGE--IRTLRLISERDSMKQKMVIAVRDHGQPSLSTTATLNI 673 Score = 99.5 bits (237), Expect = 1e-18 Identities = 82/278 (29%), Positives = 124/278 (44%), Gaps = 12/278 (4%) Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVNDNEPV 580 Q F ++ +TG + + LDRE + G R + + + E+ V D+NDN P+ Sbjct: 85 QHFRLHRKTGDLFVKEKLDREELCGKADPCVLRFEIVLEEPLQSFRAEVRVFDINDNAPM 144 Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK---DREEGSFVIDPASG 637 F I E +G+ A D DVGLNG +Y L P Sbjct: 145 FPNHGPVLKIPESTPLGSRFPLQSAQDLDVGLNGLQNYTLSANAYFHLHTRFRSHGPKYA 204 Query: 638 VIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697 + K LDRE L A+DGG+P +S T + I + D+ND+ P F I Sbjct: 205 ELVLIKPLDREEQPQVCLTLTAVDGGSPAKSGTAQILIVVLDVNDNVPQFSRLVYRAQIL 264 Query: 698 ENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS--NSFSLETRQGSDKAELVTMVDLD 755 ENSP G+ + + A D DEG N + YS+ + +F + G E+ +D Sbjct: 265 ENSPNGSLVTSVSATDLDEGTNREIVYSLAQNPEGILQTFHINFENG----EIRLRGPVD 320 Query: 756 YESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAP 792 +E+ + Y++ ++A L +V + V DVNDNAP Sbjct: 321 FEA-IENYDIDVQAIDGGGLSAHSKVLVEVMDVNDNAP 357 Score = 82.2 bits (194), Expect = 2e-13 Identities = 66/244 (27%), Positives = 110/244 (45%), Gaps = 21/244 (8%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ + D ND+ PVF+ Y +VRE S + ++A D D +NA++ Y++ Sbjct: 451 EVVISDINDNPPVFKEASYTMTVRENNSPAVFIGKVQAEDLDSEENAQITYSL------- 503 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 L PE V I+ +G L S+D E + + +VKA + P+ Sbjct: 504 LPPESG-------DLSVFSYISINSNNGKLYALRSMDYEAIQAFQFVVKAVN-GGPLP-- 553 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTY-TVSVDEDI--SVTD-NPVIAKIKATDADVGANS 185 LSS + V ++D NDN P + S D+ V + ++ K+ A D D G NS Sbjct: 554 LSSQIIVRVVVLDVNDNLPMILYPLQNSTSPCNDLVPRVAEVGYLVTKVVAVDGDSGQNS 613 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 + Y ++ FS+ SG++ ++ + ++VI +D G PS S T L I Sbjct: 614 WLSYELLKATDLGLFSVGRQSGEIRTLRLISERDSMKQKMVIAVRDHGQPSLSTTATLNI 673 Query: 246 NIRD 249 + D Sbjct: 674 LLVD 677 >UniRef50_Q9UJ99 Cluster: Cadherin-22 precursor; n=19; Euteleostomi|Rep: Cadherin-22 precursor - Homo sapiens (Human) Length = 828 Score = 196 bits (477), Expect = 1e-47 Identities = 166/575 (28%), Positives = 269/575 (46%), Gaps = 44/575 (7%) Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYE 218 V E+ + T+ + KI + D+D G + AI+Y I G F ID L+GD+ ++ LD E Sbjct: 71 VVEEYTGTEPLYVGKIHS-DSDEG-DGAIKYTISGEGAGTIFLIDELTGDIHAMERLDRE 128 Query: 219 QVRSYRLVIRAQDGGSPS-RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIV 277 Q Y L +A+D + ++ +I ++D+ND+ PRF + SV+E P G S++ Sbjct: 129 QKTFYTLRAQARDRATNRLLEPESEFIIKVQDINDSEPRFLHGPYIGSVAELSPTGTSVM 188 Query: 278 RVQAYDADE---GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS-GQLDRETQAKYQ 333 +V A DAD+ G +A L Y++ D ++ T+DP++G + T+ LDRE+Q +Y+ Sbjct: 189 QVMASDADDPTYGSSARLVYSVLDGEH------HFTVDPKTGVIRTAVPDLDRESQERYE 242 Query: 334 LLVTATD--GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTAT 391 +++ ATD G S + T F Y+ + E P GT V + A Sbjct: 243 VVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQESAPIGTAVGRVKAE 302 Query: 392 DAD--EDNRLHYEITGGNTRGR--FSIT--SQNGRGLITVAQPLDFKQERRYVLTVSA-- 443 D+D E+ + Y + ++ G F +T S +I V + LDF+ + + + + A Sbjct: 303 DSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIVVQKRLDFESQPVHTVILEALN 362 Query: 444 -------TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496 D G D A+V++ +TD + P F V EDA +G+ V VV+A D Sbjct: 363 KFVDPRFADLGTFRDQAIVRVAVTDVDE-PPEFRPPSGLLEVQEDAQVGSLVGVVTARDP 421 Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556 D N + Y++ E + DQ F I+ TGAI T K LDRET + +TV A + Sbjct: 422 DAA-NRPVRYAIDRE------SDLDQIFDIDADTGAIVTGKGLDRETAGWHNITVLAMEA 474 Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG-R 615 + + I ++DVNDN P Y A + EDA G + + D D G R Sbjct: 475 DNHAQLSRASLRIRILDVNDNPPELATP-YEAAVCEDAKPGQLIQTISVVDRDEPQGGHR 533 Query: 616 IHYELDPKDREEGSF----VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671 ++ L P+ F + D + V + +R+ L + +D G P SST Sbjct: 534 FYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVFFLPILVVDSGPPTLSSTG 593 Query: 672 IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706 + I+I + S + + F ++ + G I Sbjct: 594 TLTIRICGCDSSGTIQSCNTTAFVMAASLSPGALI 628 Score = 161 bits (390), Expect = 3e-37 Identities = 143/503 (28%), Positives = 236/503 (46%), Gaps = 32/503 (6%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +F ID +G + LDRE+ YT+ +A D+A+ + L + + + D ND+ P Sbjct: 109 IFLIDELTGDIHAMERLDREQKTFYTLRAQARDRAT--NRLLEPESEFIIKVQDINDSEP 166 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDAD---VGANSAIRYAIIGGNTQMQFSIDSL 205 +F Y SV E +S T V+ ++ A+DAD G+++ + Y+++ G + F++D Sbjct: 167 RFLHGPYIGSVAE-LSPTGTSVM-QVMASDADDPTYGSSARLVYSVLDG--EHHFTVDPK 222 Query: 206 SGDV-SLVKTLDYEQVRSYRLVIRAQD--GGSPSRSNTTQLLINIRDVNDNAPRFYTSLF 262 +G + + V LD E Y +VI+A D G S +T + I + DVNDN PRF ++ Sbjct: 223 TGVIRTAVPDLDRESQERYEVVIQATDMAGQLGGLSGSTTVTIVVTDVNDNPPRFPQKMY 282 Query: 263 QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI--DPRSGWVYT 320 Q S+ E+ PIG ++ RV+A D+D G N ++TY + D+ +G +T D + + Sbjct: 283 QFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHLKDESSSGGDVFKVTTDSDTQEAIIVV 342 Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX------XFMPGQYEVE 374 +LD E+Q + +++ A + PR A F P +E Sbjct: 343 QKRLDFESQPVHTVILEALNKFVDPRFADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLE 402 Query: 375 LAEDEPPGTPVVTLTATDADEDNR-LHYEITGGNTRGR-FSITSQNGRGLITVAQPLDFK 432 + ED G+ V +TA D D NR + Y I + + F I + G I + LD + Sbjct: 403 VQEDAQVGSLVGVVTARDPDAANRPVRYAIDRESDLDQIFDIDADT--GAIVTGKGLDRE 460 Query: 433 QERRYVLTVSA--TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 + +TV A D+ + A ++I I D N+ P PY A+V EDA G + Sbjct: 461 TAGWHNITVLAMEADNHAQLSRASLRIRILDVNDNPPELA-TPYEAAVCEDAKPGQLIQT 519 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAH-HDQQFVINPQTGAITTNKL-LDRETMSGYL 548 +S D D Q + + EA ++ H I T A+ T + +R+ + Sbjct: 520 ISVVDRD---EPQGGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVFF 576 Query: 549 LTVTARDGGVPSLSDTTDVEISV 571 L + D G P+LS T + I + Sbjct: 577 LPILVVDSGPPTLSSTGTLTIRI 599 Score = 154 bits (374), Expect = 3e-35 Identities = 134/427 (31%), Positives = 202/427 (47%), Gaps = 42/427 (9%) Query: 391 TDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR 449 +D+DE D + Y I+G F I G I + LD +Q+ Y L A D Sbjct: 88 SDSDEGDGAIKYTISGEGAGTIFLIDELTGD--IHAMERLDREQKTFYTLRAQARDRATN 145 Query: 450 ---SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD---VGINAQ 503 + I + D N+ P F + PY SV E +P GT+V+ V A+D+D G +A+ Sbjct: 146 RLLEPESEFIIKVQDINDSEPRFLHGPYIGSVAELSPTGTSVMQVMASDADDPTYGSSAR 205 Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL-LDRETMSGYLLTVTARD--GGVPS 560 + YS+ + E HH F ++P+TG I T LDRE+ Y + + A D G + Sbjct: 206 LVYSV---LDGE---HH---FTVDPKTGVIRTAVPDLDRESQERYEVVIQATDMAGQLGG 256 Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620 LS +T V I V DVNDN P F Q++Y +I E A +GT+V +V A D+DVG N + Y L Sbjct: 257 LSGSTTVTIVVTDVNDNPPRFPQKMYQFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHL 316 Query: 621 DPKDREEGS-FVI----DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV---- 671 + G F + D +I K LD ES H + A++ P+ + + Sbjct: 317 KDESSSGGDVFKVTTDSDTQEAIIVVQKRLDFESQPVHTVILEALNKFVDPRFADLGTFR 376 Query: 672 ---IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-K 727 IV + + D+ D PP F + E++ +G+ +G + A DPD N V Y+I + Sbjct: 377 DQAIVRVAVTDV-DEPPEFRPPSGLLEVQEDAQVGSLVGVVTARDPD-AANRPVRYAIDR 434 Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESP--RKKYELVIRAASPPLWNDVRVEILVT 785 D F ++ +D +VT LD E+ L + A + + + I + Sbjct: 435 ESDLDQIFDID----ADTGAIVTGKGLDRETAGWHNITVLAMEADNHAQLSRASLRIRIL 490 Query: 786 DVNDNAP 792 DVNDN P Sbjct: 491 DVNDNPP 497 Score = 99.1 bits (236), Expect = 2e-18 Identities = 92/349 (26%), Positives = 150/349 (42%), Gaps = 27/349 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND+ P F + Y+ S++E A GT V +KA D D+G+N ++ Y + Sbjct: 265 IVVTDVNDNPPRFPQKMYQFSIQESAPIGTAVGRVKAEDSDVGENTDMTYHL-------- 316 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +D D D + ++ + LD E +TV+++A ++ V R Sbjct: 317 --KDESSSGGDVFKVTTD---SDTQEAIIVVQKRLDFESQPVHTVILEALNKF--VDPRF 369 Query: 131 SSTATIH----VNI-IDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 + T V + + D D P+F + + V ED V ++ + A D D AN Sbjct: 370 ADLGTFRDQAIVRVAVTDVDEPPEFRPPSGLLEVQEDAQV--GSLVGVVTARDPD-AANR 426 Query: 186 AIRYAIIGGNTQMQ-FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 +RYAI + Q F ID+ +G + K LD E + + + A + + ++ + L Sbjct: 427 PVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRETAGWHNITVLAMEADNHAQLSRASLR 486 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 I I DVNDN P T ++ +V E+ G I + D DE Y + N Sbjct: 487 IRILDVNDNPPELATP-YEAAVCEDAKPGQLIQTISVVDRDEPQGGHRFYFRLVPEAPSN 545 Query: 305 VDLP-ITIDPRSGWVYTSG-QLDRETQAKYQLLVTATDGGDPPRSATAT 351 + I + V+T +R+ Q + L + D G P S+T T Sbjct: 546 PHFSLLDIQDNTAAVHTQHVGFNRQEQDVFFLPILVVDSGPPTLSSTGT 594 Score = 46.8 bits (106), Expect = 0.009 Identities = 49/204 (24%), Positives = 86/204 (42%), Gaps = 13/204 (6%) Query: 51 DIGKNAEVEYTIELVTA-DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREK 109 ++ ++A+V + +VTA D + +F ID +GA++T LDRE Sbjct: 402 EVQEDAQVGSLVGVVTARDPDAANRPVRYAIDRESDLDQIFDIDADTGAIVTGKGLDRET 461 Query: 110 VARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP 169 + + V A + + S A++ + I+D NDN P+ + Y +V ED Sbjct: 462 AGWHNITVLAMEADNHAQ---LSRASLRIRILDVNDNPPELA-TPYEAAVCED--AKPGQ 515 Query: 170 VIAKIKATDAD--VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT----LDYEQVRSY 223 +I I D D G + + + FS+ + + + V T + ++ + Sbjct: 516 LIQTISVVDRDEPQGGHRFYFRLVPEAPSNPHFSLLDIQDNTAAVHTQHVGFNRQEQDVF 575 Query: 224 RLVIRAQDGGSPSRSNTTQLLINI 247 L I D G P+ S+T L I I Sbjct: 576 FLPILVVDSGPPTLSSTGTLTIRI 599 >UniRef50_Q66S83 Cluster: Protocadherin 10-like protein; n=1; Oikopleura dioica|Rep: Protocadherin 10-like protein - Oikopleura dioica (Tunicate) Length = 900 Score = 195 bits (475), Expect = 2e-47 Identities = 153/529 (28%), Positives = 250/529 (47%), Gaps = 33/529 (6%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLI 423 F + + L E GT + ATD D + Y + F I +G I Sbjct: 210 FSESTFHLSLPESAEIGTILRLSPATDDDTFQYQVKKYFLESEQKPIFFKIAENSGNFQI 269 Query: 424 T---VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 + + LD + R+VL + A D GGR A + I I D N+++P+FE++ V E Sbjct: 270 PQVELIRELDVNKRARHVLKIIAEDGGGRRGEAELIIEIEDINDHSPIFESSQIKVDVSE 329 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 +A I + + + A+D+D GIN ++ YS ++ +V ++F +N TG +T K LD Sbjct: 330 NASIASQITTLYASDADKGINGEVVYSFQENVNPISVT---EKFNLNRSTGELTIAKSLD 386 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK-QQLYTA--NIMEDALVG 597 E+ ++L V A D GV S T V I+++D NDN P + L +A I EDA +G Sbjct: 387 FESAEKFVLHVKAEDKGVGSSPAYTTVVINLIDENDNSPQIRISWLGSAPEKIAEDADLG 446 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG---VIRTNKALDRESVATHD 654 ++ V D D N IH E+ + F ++ S +++T LDRE + ++ Sbjct: 447 AYIALVNVQDDD---NDEIHLEI----QNSSDFELENNSRNRYILKTKSYLDRERIKNYN 499 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 LK +A D G P + + + I +ED+ND+ P F +I EN+ G I +I A D Sbjct: 500 LKLIARDSGFPVRETIENLKIIVEDVNDNAPFFRHGQYNVHIDENNEPGAVILQILAEDQ 559 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--- 771 DEG NA + Y++ D S F +++ G+ A + +D + + + I AS Sbjct: 560 DEGQNAELSYAL--DDSSGLFEIDSENGNIIA--LESIDAEKHTNGTDFVSFIIIASDHG 615 Query: 772 -PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYR 830 P L V++ + D+N+ P F+ K+ G++ A D D T K+ + Sbjct: 616 QPSLSGFTEVKVFINDLNEFQPSFMSRNYNFSIEKNSKIGASVGQLEANDMDKTAKMHFS 675 Query: 831 ILSGNNANLILLNETTGSMTLSPQL--NTNVPKLATMEVSVTDGVNEIK 877 + N +N+ TG ++LS L +++P V+VTD +K Sbjct: 676 LERENLP--FSINDRTGEISLSRSLLNFSDIPVFYQFRVAVTDSEKRLK 722 Score = 194 bits (474), Expect = 2e-47 Identities = 157/575 (27%), Positives = 265/575 (46%), Gaps = 41/575 (7%) Query: 88 DVFRIDGRSGALLTRASLDREKVA--RYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145 + ID SG L T+ +DREK+ + ++ ASP + + I + I+D ND Sbjct: 148 EYLEIDAHSGDLTTKKEIDREKICGIKKECALEIEVLASP--QQFFNVFNIRLLILDLND 205 Query: 146 NYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSL 205 N P+FSE T+ +S+ E + ++ ATD D +Y + + F I Sbjct: 206 NSPKFSESTFHLSLPESAEI--GTILRLSPATDDDTFQYQVKKYFLESEQKPIFFKIAEN 263 Query: 206 SGD-----VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260 SG+ V L++ LD + + L I A+DGG R +L+I I D+ND++P F +S Sbjct: 264 SGNFQIPQVELIRELDVNKRARHVLKIIAEDGGG--RRGEAELIIEIEDINDHSPIFESS 321 Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYT 320 + VSEN I I + A DAD+G+N E+ Y+ + +V ++ +G + Sbjct: 322 QIKVDVSENASIASQITTLYASDADKGINGEVVYSFQENVNPISVTEKFNLNRSTGELTI 381 Query: 321 SGQLDRETQAKYQLLVTATD---GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377 + LD E+ K+ L V A D G P + G ++AE Sbjct: 382 AKSLDFESAEKFVLHVKAEDKGVGSSPAYTTVVINLIDENDNSPQIRISWLGSAPEKIAE 441 Query: 378 DEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSI-TSQNGRGLITVAQPLDFKQERR 436 D G + + D D+++ +H EI + F + + R ++ LD ++ + Sbjct: 442 DADLGAYIALVNVQD-DDNDEIHLEIQNSSD---FELENNSRNRYILKTKSYLDRERIKN 497 Query: 437 YVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494 Y L + A DSG R ++I + D N+ AP F + Y + E+ G +L + A Sbjct: 498 YNLKLIARDSGFPVRETIENLKIIVEDVNDNAPFFRHGQYNVHIDENNEPGAVILQILAE 557 Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG----YLLT 550 D D G NA+++Y+L F I+ + G I + +D E + Sbjct: 558 DQDEGQNAELSYALDDS---------SGLFEIDSENGNIIALESIDAEKHTNGTDFVSFI 608 Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610 + A D G PSLS T+V++ + D+N+ +P F + Y +I +++ +G SV Q+ A D D Sbjct: 609 IIASDHGQPSLSGFTEVKVFINDLNEFQPSFMSRNYNFSIEKNSKIGASVGQLEANDMD- 667 Query: 611 GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645 ++H+ L +RE F I+ +G I +++L Sbjct: 668 -KTAKMHFSL---ERENLPFSINDRTGEISLSRSL 698 Score = 179 bits (435), Expect = 1e-42 Identities = 159/577 (27%), Positives = 259/577 (44%), Gaps = 48/577 (8%) Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR--LVIRAQDGGSPSR-SNTTQLLI 245 + II G ID+ SGD++ K +D E++ + + + SP + N + + Sbjct: 139 FKIIEGQNHEYLEIDAHSGDLTTKKEIDREKICGIKKECALEIEVLASPQQFFNVFNIRL 198 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 I D+NDN+P+F S F S+ E+ IG +I+R+ D+ ++ + + Sbjct: 199 LILDLNDNSPKFSESTFHLSLPESAEIG-TILRLSPATDDDTFQYQVKKYFLESE---QK 254 Query: 306 DLPITIDPRSG-----WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 + I SG V +LD +A++ L + A DGG R A Sbjct: 255 PIFFKIAENSGNFQIPQVELIRELDVNKRARHVLKIIAEDGGG--RRGEAELIIEIEDIN 312 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQ--- 417 F Q +V+++E+ + + TL A+DAD+ + S+T + Sbjct: 313 DHSPIFESSQIKVDVSENASIASQITTLYASDADKGINGEVVYSFQENVNPISVTEKFNL 372 Query: 418 -NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFE---- 470 G +T+A+ LDF+ ++VL V A D G S A V IN+ D N+ +P Sbjct: 373 NRSTGELTIAKSLDFESAEKFVLHVKAEDKGVGSSPAYTTVVINLIDENDNSPQIRISWL 432 Query: 471 -NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 +AP + EDA +G + +V+ D D N +I + + E + ++++ Sbjct: 433 GSAP--EKIAEDADLGAYIALVNVQDDD---NDEIHLEIQNSSDFELENNSRNRYILK-- 485 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589 T LDRE + Y L + ARD G P +++I V DVNDN P F+ Y + Sbjct: 486 -----TKSYLDRERIKNYNLKLIARDSGFPVRETIENLKIIVEDVNDNAPFFRHGQYNVH 540 Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES 649 I E+ G + Q+ A D D G N + Y LD G F ID +G I +++D E Sbjct: 541 IDENNEPGAVILQILAEDQDEGQNAELSYALDD---SSGLFEIDSENGNIIALESIDAEK 597 Query: 650 VATH----DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 +A D G P S V + I D+N+ P F S F I +NS IG + Sbjct: 598 HTNGTDFVSFIIIASDHGQPSLSGFTEVKVFINDLNEFQPSFMSRNYNFSIEKNSKIGAS 657 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 +G++ A+D D+ A +H+S++ ++ FS+ R G Sbjct: 658 VGQLEANDMDK--TAKMHFSLE--RENLPFSINDRTG 690 Score = 158 bits (383), Expect = 2e-36 Identities = 139/496 (28%), Positives = 222/496 (44%), Gaps = 45/496 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D NDHSP+FE Q + V E AS + + TL A+D D G N EV Y+ + + + Sbjct: 306 IEIEDINDHSPIFESSQIKVDVSENASIASQITTLYASDADKGINGEVVYSFQ----ENV 361 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 NP V + F ++ +G L SLD E ++ + VKA D+ S Sbjct: 362 NP-----------ISVTEKFNLNRSTGELTIAKSLDFESAEKFVLHVKAEDKGVGSSPAY 410 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + T+ +N+ID+NDN PQ ++ S E I+ D + A I + N I Sbjct: 411 T---TVVINLIDENDNSPQI-RISWLGSAPEKIA-EDADLGAYIALVNVQDDDNDEIHLE 465 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKT---LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 I F +++ S + ++KT LD E++++Y L + A+D G P R L I + Sbjct: 466 I---QNSSDFELENNSRNRYILKTKSYLDRERIKNYNLKLIARDSGFPVRETIENLKIIV 522 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 DVNDNAP F + + EN G I+++ A D DEG NAEL+Y + D +G + Sbjct: 523 EDVNDNAPFFRHGQYNVHIDENNEPGAVILQILAEDQDEGQNAELSYALDDS--SGLFE- 579 Query: 308 PITIDPRSGWVYTSGQLDRETQAK----YQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 ID +G + +D E ++ A+D G P S Sbjct: 580 ---IDSENGNIIALESIDAEKHTNGTDFVSFIIIASDHGQPSLSGFTEVKVFINDLNEFQ 636 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423 FM Y + ++ G V L A D D+ ++H+ + N FSI + G I Sbjct: 637 PSFMSRNYNFSIEKNSKIGASVGQLEANDMDKTAKMHFSLERENL--PFSINDRTGE--I 692 Query: 424 TVAQP-LDFKQ-ERRYVLTVSATDSGGR---SDTAMVQINITDANNYAPVFENAPYTASV 478 ++++ L+F Y V+ TDS R D A V + ++++ ++A A V Sbjct: 693 SLSRSLLNFSDIPVFYQFRVAVTDSEKRLKTKDLAEVVVYVSESFRSLENIDDASKAAVV 752 Query: 479 FEDAPIGTTVLVVSAT 494 G +++++ T Sbjct: 753 LVGIFAGAVIILITIT 768 Score = 66.1 bits (154), Expect = 1e-08 Identities = 56/210 (26%), Positives = 98/210 (46%), Gaps = 34/210 (16%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +I V D ND++P F QY + E G +L + A DQD G+NAE+ Y ++ D+ Sbjct: 519 KIIVEDVNDNAPFFRHGQYNVHIDENNEPGAVILQILAEDQDEGQNAELSYALD----DS 574 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYT----VLVKATDQASP 125 +F ID +G ++ S+D EK T ++ A+D P Sbjct: 575 -----------------SGLFEIDSENGNIIALESIDAEKHTNGTDFVSFIIIASDHGQP 617 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 LS + V I D N+ P F + Y S++++ + + +++A D D A Sbjct: 618 ---SLSGFTEVKVFINDLNEFQPSFMSRNYNFSIEKNSKI--GASVGQLEANDMDKTAK- 671 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTL 215 + +++ N + FSI+ +G++SL ++L Sbjct: 672 -MHFSLEREN--LPFSINDRTGEISLSRSL 698 Score = 63.7 bits (148), Expect = 7e-08 Identities = 65/281 (23%), Positives = 118/281 (41%), Gaps = 13/281 (4%) Query: 632 IDPASGVIRTNKALDRESVATHDLK-AVAIDGGTPPQSSTVIVHIK--IEDINDSPPVFE 688 ID SG + T K +DRE + + A+ I+ PQ + +I+ I D+ND+ P F Sbjct: 152 IDAHSGDLTTKKEIDREKICGIKKECALEIEVLASPQQFFNVFNIRLLILDLNDNSPKFS 211 Query: 689 SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAEL 748 + E++ IGT + A D D V Y ++ F + G+ + Sbjct: 212 ESTFHLSLPESAEIGTILRLSPATDDDTFQYQVKKYFLESEQKPIFFKIAENSGNFQIPQ 271 Query: 749 VTMV-DLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDC 807 V ++ +LD + +I + + I + D+ND++P+ + QI + ++ Sbjct: 272 VELIRELDVNKRARHVLKIIAEDGGGRRGEAELIIEIEDINDHSPIFESSQIKVDVSENA 331 Query: 808 FPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLIL----LNETTGSMTLSPQLNTNVPK 861 + A DAD + ++ Y N + LN +TG +T++ L+ + Sbjct: 332 SIASQITTLYASDADKGINGEVVYSFQENVNPISVTEKFNLNRSTGELTIAKSLDFESAE 391 Query: 862 LATMEVSVTD-GVNEIKAMMQLSVRLITEEMLLNSITVRLN 901 + V D GV A + + LI E NS +R++ Sbjct: 392 KFVLHVKAEDKGVGSSPAYTTVVINLIDEND--NSPQIRIS 430 >UniRef50_UPI000069ECF7 Cluster: UPI000069ECF7 related cluster; n=1; Xenopus tropicalis|Rep: UPI000069ECF7 UniRef100 entry - Xenopus tropicalis Length = 714 Score = 194 bits (473), Expect = 3e-47 Identities = 161/510 (31%), Positives = 247/510 (48%), Gaps = 43/510 (8%) Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSN 239 D GA+ +++Y++ G F+ID G+V + K LD E+ +R V+ A D + Sbjct: 1 DNGAHGSLKYSLHGKGANNIFTIDEERGNVFVQKALDREEHGLWRFVVLATDEEGEGLTG 60 Query: 240 TTQLLINIRDVNDNAPRFYTSL--FQESVSENVPIGYSIVRVQAYDAD---EGVNAELTY 294 ++I + D+NDNAP+F +L +V ENVP +++ + A DAD E +NA LTY Sbjct: 61 FADVIIYVVDINDNAPQFTCALSSCNANVYENVPPNTTVLEMTAVDADDKNEEINAILTY 120 Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354 +M + T N+ +I+ +G +YT G LDRE KY LLV DGG + TAT Sbjct: 121 SMLNN--TMNL---FSINANTGTIYTLGNLDREKNDKYVLLVKVIDGGGLATTGTAT--I 173 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRF 412 F + + E T V+ ++A+D D E+ L + I G+ +F Sbjct: 174 SVLDINDHVPRFTQDSWNSVILETNDINTKVLEVSASDEDIGENALLTFSIIDGDPDQKF 233 Query: 413 SITS--QNGRGLITVAQPLDFK--QERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468 +I S + I + + LD++ QER + LT+ D S + I + D N+ APV Sbjct: 234 TIESDRMTNQAEIKLKKKLDYENPQERWFNLTIKVEDP-DFSSLSFCFIELQDCNDNAPV 292 Query: 469 FENAPYT--ASVFEDAPIGTTVLVVSATDSDVGINAQITYSL--SSEISNEAVAHHDQQF 524 F AP+ + V E+ IGT + V A+D+D GIN QI YS+ SS++ E F Sbjct: 293 F-LAPFVQLSPVLENVTIGTVLTQVIASDADSGINGQIRYSIWPSSDVLGE--------F 343 Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584 ++P G + K LDRE S Y L + A D G PS + + V S++DVNDN P + Sbjct: 344 FVDP-AGFVKVKKALDREVDSQYHLVILASDEGFPSQTGSATVSFSLLDVNDNGP---EN 399 Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNG-RIHYELDPKDREEGSFVIDP---ASGVIR 640 I+ + S + A+D D NG + L + F+++ + + Sbjct: 400 TAWPQIVH---MNESSDLLYASDYDTLENGPPFRFSLPSEYTNSTDFLLNDNGNNTATVH 456 Query: 641 TNKALDRESVATHDLKAVAIDGGTPPQSST 670 +A DRE L + D G PP S+T Sbjct: 457 ALRAFDREKDKEFYLPIIITDSGNPPMSAT 486 Score = 174 bits (423), Expect = 3e-41 Identities = 132/415 (31%), Positives = 195/415 (46%), Gaps = 32/415 (7%) Query: 285 DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP 344 D G + L Y++ K N+ TID G V+ LDRE ++ +V ATD Sbjct: 1 DNGAHGSLKYSLHGKG-ANNI---FTIDEERGNVFVQKALDREEHGLWRFVVLATDEEGE 56 Query: 345 PRSATATXXXXXXXXXXXXXXFMPG--QYEVELAEDEPPGTPVVTLTATDADEDNR---- 398 + A F + E+ PP T V+ +TA DAD+ N Sbjct: 57 GLTGFADVIIYVVDINDNAPQFTCALSSCNANVYENVPPNTTVLEMTAVDADDKNEEINA 116 Query: 399 -LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQI 457 L Y + NT FSI + G + T+ LD ++ +YVL V D GG + T I Sbjct: 117 ILTYSMLN-NTMNLFSINANTGT-IYTLGN-LDREKNDKYVLLVKVIDGGGLATTGTATI 173 Query: 458 NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517 ++ D N++ P F + + + E I T VL VSA+D D+G NA +T+S+ I + Sbjct: 174 SVLDINDHVPRFTQDSWNSVILETNDINTKVLEVSASDEDIGENALLTFSI---IDGDP- 229 Query: 518 AHHDQQFVIN----PQTGAITTNKLLDRETMS--GYLLTVTARDGGVPSLSDTTDVEISV 571 DQ+F I I K LD E + LT+ D P S + I + Sbjct: 230 ---DQKFTIESDRMTNQAEIKLKKKLDYENPQERWFNLTIKVED---PDFSSLSFCFIEL 283 Query: 572 VDVNDNEPVFKQQ-LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630 D NDN PVF + + ++E+ +GT ++QV A+DAD G+NG+I Y + P G F Sbjct: 284 QDCNDNAPVFLAPFVQLSPVLENVTIGTVLTQVIASDADSGINGQIRYSIWPSSDVLGEF 343 Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685 +DPA G ++ KALDRE + + L +A D G P Q+ + V + D+ND+ P Sbjct: 344 FVDPA-GFVKVKKALDREVDSQYHLVILASDEGFPSQTGSATVSFSLLDVNDNGP 397 Score = 160 bits (389), Expect = 4e-37 Identities = 139/475 (29%), Positives = 226/475 (47%), Gaps = 57/475 (12%) Query: 11 INVLDCNDHSPVFE--MQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTAD 68 I V+D ND++P F + A+V E TTVL + A D D KN E+ ++T Sbjct: 66 IYVVDINDNAPQFTCALSSCNANVYENVPPNTTVLEMTAVDAD-DKNEEIN---AILTYS 121 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 LN ++F I+ +G + T +LDREK +Y +LVK D Sbjct: 122 MLN-------------NTMNLFSINANTGTIYTLGNLDREKNDKYVLLVKVIDGGG---- 164 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 L++T T ++++D ND+ P+F++ ++ + E + N + ++ A+D D+G N+ + Sbjct: 165 -LATTGTATISVLDINDHVPRFTQDSWNSVILETNDI--NTKVLEVSASDEDIGENALLT 221 Query: 189 YAIIGGNTQMQFSIDS----LSGDVSLVKTLDYE--QVRSYRLVIRAQDGGSPSRSNTTQ 242 ++II G+ +F+I+S ++ L K LDYE Q R + L I+ +D P S+ + Sbjct: 222 FSIIDGDPDQKFTIESDRMTNQAEIKLKKKLDYENPQERWFNLTIKVED---PDFSSLSF 278 Query: 243 LLINIRDVNDNAPRFYTSLFQES-VSENVPIGYSIVRVQAYDADEGVNAELTYTM-TDKD 300 I ++D NDNAP F Q S V ENV IG + +V A DAD G+N ++ Y++ D Sbjct: 279 CFIELQDCNDNAPVFLAPFVQLSPVLENVTIGTVLTQVIASDADSGINGQIRYSIWPSSD 338 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 G +DP +G+V LDRE ++Y L++ A+D G P ++ +AT Sbjct: 339 VLGE----FFVDP-AGFVKVKKALDREVDSQYHLVILASDEGFPSQTGSATVSFSLLDVN 393 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DN--RLHYEITGGNTRGRFSITSQ 417 V + E L A+D D +N + + T + + Sbjct: 394 DNGPENTAWPQIVHMNESSD------LLYASDYDTLENGPPFRFSLPSEYTNSTDFLLND 447 Query: 418 NGRGLITV--AQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINIT--DANNYA 466 NG TV + D ++++ + L + TDSG S T M+ IN +N YA Sbjct: 448 NGNNTATVHALRAFDREKDKEFYLPIIITDSGNPPMSATNMLLINYVCHCSNGYA 502 Score = 145 bits (351), Expect = 2e-32 Identities = 131/409 (32%), Positives = 189/409 (46%), Gaps = 34/409 (8%) Query: 399 LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT--AMVQ 456 L Y + G F+I + RG + V + LD ++ + V ATD G T A V Sbjct: 8 LKYSLHGKGANNIFTIDEE--RGNVFVQKALDREEHGLWRFVVLATDEEGEGLTGFADVI 65 Query: 457 INITDANNYAPVFENA--PYTASVFEDAPIGTTVLVVSATDSD---VGINAQITYSLSSE 511 I + D N+ AP F A A+V+E+ P TTVL ++A D+D INA +TYS+ + Sbjct: 66 IYVVDINDNAPQFTCALSSCNANVYENVPPNTTVLEMTAVDADDKNEEINAILTYSMLNN 125 Query: 512 ISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571 N F IN TG I T LDRE Y+L V DGG L+ T ISV Sbjct: 126 TMN--------LFSINANTGTIYTLGNLDREKNDKYVLLVKVIDGG--GLATTGTATISV 175 Query: 572 VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631 +D+ND+ P F Q + + I+E + T V +V A+D D+G N + + + D ++ F Sbjct: 176 LDINDHVPRFTQDSWNSVILETNDINTKVLEVSASDEDIGENALLTFSIIDGDPDQ-KFT 234 Query: 632 IDPA----SGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687 I+ I+ K LD E+ + I P SS I+++D ND+ PVF Sbjct: 235 IESDRMTNQAEIKLKKKLDYENPQERWFN-LTIKVEDPDFSSLSFCFIELQDCNDNAPVF 293 Query: 688 ESDCLTFY-ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746 + + + EN IGT + ++ A D D G N + YSI D G K Sbjct: 294 LAPFVQLSPVLENVTIGTVLTQVIASDADSGINGQIRYSIWPSSDVLGEFFVDPAGFVKV 353 Query: 747 ELVTMVDLDYESPRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAP 792 + +D + +S +Y LVI A+ P V + DVNDN P Sbjct: 354 K--KALDREVDS---QYHLVILASDEGFPSQTGSATVSFSLLDVNDNGP 397 Score = 130 bits (313), Expect = 7e-28 Identities = 99/303 (32%), Positives = 146/303 (48%), Gaps = 17/303 (5%) Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556 D G + + YSL + +N F I+ + G + K LDRE + V A D Sbjct: 1 DNGAHGSLKYSLHGKGANNI-------FTIDEERGNVFVQKALDREEHGLWRFVVLATDE 53 Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYT--ANIMEDALVGTSVSQVGATDAD---VG 611 L+ DV I VVD+NDN P F L + AN+ E+ T+V ++ A DAD Sbjct: 54 EGEGLTGFADVIIYVVDINDNAPQFTCALSSCNANVYENVPPNTTVLEMTAVDADDKNEE 113 Query: 612 LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671 +N + Y + + F I+ +G I T LDRE + L IDGG + T Sbjct: 114 INAILTYSM--LNNTMNLFSINANTGTIYTLGNLDREKNDKYVLLVKVIDGGGLATTGTA 171 Query: 672 IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD 731 I + DIND P F D I E + I T + E+ A D D G NA++ +SI GD Sbjct: 172 T--ISVLDINDHVPRFTQDSWNSVILETNDINTKVLEVSASDEDIGENALLTFSIIDGDP 229 Query: 732 SNSFSLETRQGSDKAELVTMVDLDYESPRKK-YELVIRAASPPLWNDVRVEILVTDVNDN 790 F++E+ + +++AE+ LDYE+P+++ + L I+ P + I + D NDN Sbjct: 230 DQKFTIESDRMTNQAEIKLKKKLDYENPQERWFNLTIKVEDPDFSSLSFCFIELQDCNDN 289 Query: 791 APV 793 APV Sbjct: 290 APV 292 Score = 129 bits (312), Expect = 9e-28 Identities = 126/499 (25%), Positives = 225/499 (45%), Gaps = 37/499 (7%) Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 ++F ID G + + +LDRE+ + +V ATD+ + L+ A + + ++D NDN Sbjct: 19 NIFTIDEERGNVFVQKALDREEHGLWRFVVLATDEEG---EGLTGFADVIIYVVDINDNA 75 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD---VGANSAIRYAIIGGNTQMQFSIDS 204 PQF+ + + + +V N + ++ A DAD N+ + Y+++ NT FSI++ Sbjct: 76 PQFTCALSSCNANVYENVPPNTTVLEMTAVDADDKNEEINAILTYSML-NNTMNLFSINA 134 Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 +G + + LD E+ Y L+++ DGG + + T I++ D+ND+ PRF + Sbjct: 135 NTGTIYTLGNLDREKNDKYVLLVKVIDGGGLATTGTA--TISVLDINDHVPRFTQDSWNS 192 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 + E I ++ V A D D G NA LT+++ D D + + +L Sbjct: 193 VILETNDINTKVLEVSASDEDIGENALLTFSIIDGDPDQKFTIESDRMTNQAEIKLKKKL 252 Query: 325 DRET-QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE-LAEDEPPG 382 D E Q ++ L + DP S+ + F+ ++ + E+ G Sbjct: 253 DYENPQERWFNLTIKVE--DPDFSSLSFCFIELQDCNDNAPVFLAPFVQLSPVLENVTIG 310 Query: 383 TPVVTLTATDADE--DNRLHYEI-TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL 439 T + + A+DAD + ++ Y I + G F + + G + V + LD + + +Y L Sbjct: 311 TVLTQVIASDADSGINGQIRYSIWPSSDVLGEFFV---DPAGFVKVKKALDREVDSQYHL 367 Query: 440 TVSATDSGGRSDT--AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497 + A+D G S T A V ++ D N+ P EN + V + + ++ A+D D Sbjct: 368 VILASDEGFPSQTGSATVSFSLLDVNDNGP--ENTAWPQIVH----MNESSDLLYASDYD 421 Query: 498 VGINA-QITYSLSSEISNEAVAHHDQQFVINP---QTGAITTNKLLDRETMSGYLLTVTA 553 N +SL SE +N F++N T + + DRE + L + Sbjct: 422 TLENGPPFRFSLPSEYTNST------DFLLNDNGNNTATVHALRAFDREKDKEFYLPIII 475 Query: 554 RDGGVPSLSDTTDVEISVV 572 D G P +S T + I+ V Sbjct: 476 TDSGNPPMSATNMLLINYV 494 Score = 63.3 bits (147), Expect = 9e-08 Identities = 67/251 (26%), Positives = 117/251 (46%), Gaps = 39/251 (15%) Query: 2 SVPFCIHQQINVLDCNDHSPVFEMQQYEAS-VREGASSGTTVLTLKATDQDIGKNAEVEY 60 S+ FC I + DCND++PVF + S V E + GT + + A+D D G N ++ Y Sbjct: 275 SLSFCF---IELQDCNDNAPVFLAPFVQLSPVLENVTIGTVLTQVIASDADSGINGQIRY 331 Query: 61 TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT 120 +I ++D L F +D +G + + +LDRE ++Y +++ A+ Sbjct: 332 SI-WPSSDVLGE-----------------FFVD-PAGFVKVKKALDREVDSQYHLVILAS 372 Query: 121 DQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD 180 D+ P + +AT+ +++D NDN P+ + V ++E + + A+D D Sbjct: 373 DEGFPSQ---TGSATVSFSLLDVNDNGPENTAWPQIVHMNESSDL--------LYASDYD 421 Query: 181 VGANS-AIRYAIIGGNT-QMQFSIDSLSGDVSLVKTL---DYEQVRSYRLVIRAQDGGSP 235 N R+++ T F ++ + + V L D E+ + + L I D G+P Sbjct: 422 TLENGPPFRFSLPSEYTNSTDFLLNDNGNNTATVHALRAFDREKDKEFYLPIIITDSGNP 481 Query: 236 SRSNTTQLLIN 246 S T LLIN Sbjct: 482 PMSATNMLLIN 492 >UniRef50_UPI0000ECABB6 Cluster: Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2).; n=2; Gallus gallus|Rep: Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2). - Gallus gallus Length = 1099 Score = 194 bits (472), Expect = 4e-47 Identities = 183/627 (29%), Positives = 275/627 (43%), Gaps = 60/627 (9%) Query: 92 IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151 ++ G L T +DRE++ R++ + +++L+ + V ++D ND+ P+F Sbjct: 78 VESGDGELSTAGRVDREQLCRHSDPCWVSFDVL-AAEQLA-LIHVEVQVLDINDHAPRFP 135 Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG---- 207 + + E S+ + I +A DAD G N+ YA+ + F+++ +SG Sbjct: 136 TPELELEMSESASLQMH--IPLDRALDADTGPNAHCSYAL---SPSEHFALEVVSGSDGT 190 Query: 208 ---DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 ++ ++K +D E S+ LV+ A D G P RS T + + + D NDN+P F S Sbjct: 191 KHAELVVIKEVDRELHSSFDLVLTAADHGEPPRSGTALIKVIVLDSNDNSPVFAESSLVV 250 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 V E+ +G +V V A D D+G N E+ Y+++ K V ID R G V L Sbjct: 251 EVREDALLGTLLVTVTATDPDQGPNGEIEYSLS-KHAPPEVLSTFAIDARMGSVVLRRPL 309 Query: 325 DRETQAKYQLLVTATD-GGDP-PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382 D E Y+L V A D G +P P L+E P Sbjct: 310 DYEETHAYELDVQARDLGANPIPAHCKVLVRVLDVNDNAPDVRVTWAARAPVLSEAVPKD 369 Query: 383 TPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440 + V +TA+D D N R+H ++ G+ R T+ + L+T A LD + Y LT Sbjct: 370 SFVALVTASDPDSGNNGRVHCSLSPGDEHFRLKQTNSHSYLLMTNAM-LDRELRAEYNLT 428 Query: 441 VSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498 + A D G S + I I+D N+ AP FE Y +V E+ + +L V ATD D+ Sbjct: 429 LVARDQGEHSLAVWKHLTICISDVNDNAPSFERTSYERAVEENGDVPAFLLTVRATDPDL 488 Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558 G N ++TYS+ V+ I+P +G IT + D E MS VTA DGG Sbjct: 489 GFNGKVTYSIRDSTVLGLVS-------IDPISGDITALRAFDHEQMSSLEFLVTAEDGGH 541 Query: 559 PSLSDTTDVEISVVDVNDNEPVFKQQ-----------LYTA------------NIMEDAL 595 P L+ V + V+D NDN PV + L +A + ME L Sbjct: 542 PVLASNVTVRLEVLDQNDNAPVVTEPPLVRGMATLSVLVSAETGCVWVTSGNGSAMETVL 601 Query: 596 VGTSVSQ------VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES 649 S S + A D D G NG + Y++ D G V+DP SG N + Sbjct: 602 ANVSCSDTPLLFTIVARDGDSGRNGALRYDIMGGD-AAGLVVLDPLSGQAFLNASNASRL 660 Query: 650 VATHDLKAVAI-DGGTPPQSSTVIVHI 675 T AV I DGG P + V + Sbjct: 661 AGTQQDLAVRISDGGDEPLHTQACVRL 687 Score = 176 bits (428), Expect = 8e-42 Identities = 155/556 (27%), Positives = 249/556 (44%), Gaps = 24/556 (4%) Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312 +A T Q + E VP G +++ A + G + E+ G P+ ++ Sbjct: 23 DAQEVATITVQYRLFEEVPEG-TVIGTLAEHFEHGESGEMGENFRLLQSPGM--FPLHVE 79 Query: 313 PRSGWVYTSGQLDRETQAKYQ-LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371 G + T+G++DRE ++ + D + A F + Sbjct: 80 SGDGELSTAGRVDREQLCRHSDPCWVSFDVLAAEQLALIHVEVQVLDINDHAPRFPTPEL 139 Query: 372 EVELAEDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNG--RGLITVAQ 427 E+E++E + A DAD H Y ++ ++ +G + V + Sbjct: 140 ELEMSESASLQMHIPLDRALDADTGPNAHCSYALSPSEHFALEVVSGSDGTKHAELVVIK 199 Query: 428 PLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIG 485 +D + + L ++A D G RS TA++++ + D+N+ +PVF + V EDA +G Sbjct: 200 EVDRELHSSFDLVLTAADHGEPPRSGTALIKVIVLDSNDNSPVFAESSLVVEVREDALLG 259 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 T ++ V+ATD D G N +I YSLS E ++ F I+ + G++ + LD E Sbjct: 260 TLLVTVTATDPDQGPNGEIEYSLSKHAPPEVLS----TFAIDARMGSVVLRRPLDYEETH 315 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP-VFKQQLYTANIMEDALVGTS-VSQV 603 Y L V ARD G + V + V+DVNDN P V A ++ +A+ S V+ V Sbjct: 316 AYELDVQARDLGANPIPAHCKVLVRVLDVNDNAPDVRVTWAARAPVLSEAVPKDSFVALV 375 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 A+D D G NGR+H L P D + S ++ TN LDRE A ++L VA D G Sbjct: 376 TASDPDSGNNGRVHCSLSPGDEHFRLKQTNSHSYLLMTNAMLDRELRAEYNLTLVARDQG 435 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 + + I I D+ND+ P FE + EN + + +RA DPD G N V Sbjct: 436 EHSLAVWKHLTICISDVNDNAPSFERTSYERAVEENGDVPAFLLTVRATDPDLGFNGKVT 495 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRV 780 YSI+ S++ G ++ + D+E E ++ A P L ++V V Sbjct: 496 YSIRDSTVLGLVSIDPISG----DITALRAFDHEQ-MSSLEFLVTAEDGGHPVLASNVTV 550 Query: 781 EILVTDVNDNAPVMKD 796 + V D NDNAPV+ + Sbjct: 551 RLEVLDQNDNAPVVTE 566 Score = 159 bits (386), Expect = 1e-36 Identities = 150/550 (27%), Positives = 238/550 (43%), Gaps = 42/550 (7%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 IH ++ VLD NDH+P F + E + E AS + +A D D G NA Y Sbjct: 118 IHVEVQVLDINDHAPRFPTPELELEMSESASLQMHIPLDRALDADTGPNAHCSY------ 171 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGA-LLTRASLDREKVARYTVLVKATDQASP 125 L+P + ++ V DG A L+ +DRE + + +++ A D P Sbjct: 172 --ALSPSE--------HFALEVVSGSDGTKHAELVVIKEVDRELHSSFDLVLTAADHGEP 221 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 S TA I V ++D NDN P F+E + V V ED + ++ + ATD D G N Sbjct: 222 PR---SGTALIKVIVLDSNDNSPVFAESSLVVEVREDALL--GTLLVTVTATDPDQGPNG 276 Query: 186 AIRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 I Y++ F+ID+ G V L + LDYE+ +Y L ++A+D G+ + Sbjct: 277 EIEYSLSKHAPPEVLSTFAIDARMGSVVLRRPLDYEETHAYELDVQARDLGANPIPAHCK 336 Query: 243 LLINIRDVNDNAP--RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 +L+ + DVNDNAP R + +SE VP + V A D D G N + +++ D Sbjct: 337 VLVRVLDVNDNAPDVRVTWAARAPVLSEAVPKDSFVALVTASDPDSGNNGRVHCSLSPGD 396 Query: 301 YTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 + L T + S + T+ LDRE +A+Y L + A D G+ + Sbjct: 397 --EHFRLKQT-NSHSYLLMTNAMLDRELRAEYNLTLVARDQGEHSLAVWKHLTICISDVN 453 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQN 418 F YE + E+ ++T+ ATD D + ++ Y I G SI + Sbjct: 454 DNAPSFERTSYERAVEENGDVPAFLLTVRATDPDLGFNGKVTYSIRDSTVLGLVSIDPIS 513 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTA 476 G IT + D +Q V+A D G + V++ + D N+ APV P Sbjct: 514 GD--ITALRAFDHEQMSSLEFLVTAEDGGHPVLASNVTVRLEVLDQNDNAPVVTEPPLVR 571 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 + T ++VSA V + + ++ + ++N + + F I + G N Sbjct: 572 G------MATLSVLVSAETGCVWVTSGNGSAMETVLANVSCSDTPLLFTIVARDGDSGRN 625 Query: 537 KLLDRETMSG 546 L + M G Sbjct: 626 GALRYDIMGG 635 Score = 83.4 bits (197), Expect = 8e-14 Identities = 74/269 (27%), Positives = 124/269 (46%), Gaps = 17/269 (6%) Query: 632 IDPASGVIRTNKALDRESVATH-DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690 ++ G + T +DRE + H D V+ D Q + + V +++ DIND P F + Sbjct: 78 VESGDGELSTAGRVDREQLCRHSDPCWVSFDVLAAEQLALIHVEVQVLDINDHAPRFPTP 137 Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD---KAE 747 L +SE++ + I RA D D GPNA Y++ S F+LE GSD AE Sbjct: 138 ELELEMSESASLQMHIPLDRALDADTGPNAHCSYAL---SPSEHFALEVVSGSDGTKHAE 194 Query: 748 LVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY 804 LV + ++D E ++LV+ AA PP ++++V D NDN+PV + ++ Sbjct: 195 LVVIKEVDREL-HSSFDLVLTAADHGEPPRSGTALIKVIVLDSNDNSPVFAESSLVVEVR 253 Query: 805 KDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLI---LLNETTGSMTLSPQLNTNV 859 +D V A D D +++Y + ++ ++ GS+ L L+ Sbjct: 254 EDALLGTLLVTVTATDPDQGPNGEIEYSLSKHAPPEVLSTFAIDARMGSVVLRRPLDYEE 313 Query: 860 PKLATMEVSVTD-GVNEIKAMMQLSVRLI 887 ++V D G N I A ++ VR++ Sbjct: 314 THAYELDVQARDLGANPIPAHCKVLVRVL 342 Score = 81.0 bits (191), Expect = 4e-13 Identities = 73/254 (28%), Positives = 109/254 (42%), Gaps = 50/254 (19%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 H I + D ND++P FE YE +V E +LT++ATD D+G N +V Y+I Sbjct: 444 HLTICISDVNDNAPSFERTSYERAVEENGDVPAFLLTVRATDPDLGFNGKVTYSIR---- 499 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 V + ID SG + + D E+++ LV A D PV Sbjct: 500 ---------------DSTVLGLVSIDPISGDITALRAFDHEQMSSLEFLVTAEDGGHPV- 543 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSE-------KTYTVSVDED------------------ 162 L+S T+ + ++D NDN P +E T +V V + Sbjct: 544 --LASNVTVRLEVLDQNDNAPVVTEPPLVRGMATLSVLVSAETGCVWVTSGNGSAMETVL 601 Query: 163 --ISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV 220 +S +D P++ I A D D G N A+RY I+GG+ +D LSG L + Sbjct: 602 ANVSCSDTPLLFTIVARDGDSGRNGALRYDIMGGDAAGLVVLDPLSGQAFLNASNASRLA 661 Query: 221 RSYR-LVIRAQDGG 233 + + L +R DGG Sbjct: 662 GTQQDLAVRISDGG 675 >UniRef50_Q4T6J0 Cluster: Chromosome undetermined SCAF8736, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome undetermined SCAF8736, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1582 Score = 192 bits (469), Expect = 9e-47 Identities = 154/575 (26%), Positives = 263/575 (45%), Gaps = 34/575 (5%) Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 ++ + I D+NDN+P F +SE+ G V +A DAD GVN Y++ D+ Sbjct: 91 RITVEITDINDNSPVFKYEEKLFEISESAVPGSKFVLDRAVDADIGVNGLKNYSLKPSDH 150 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 T + QLDRE + + LL+TA DGG+P S T Sbjct: 151 FQLRMQHHTDGNNKVEMVLHKQLDREKEEEMSLLLTAVDGGEPQMSGTVKIFVTVLDVND 210 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS-ITSQNGR 420 F+ Y+ +AE+ GT + ++ATDAD+ + +T S I + + + Sbjct: 211 NAPVFVQPVYKAAIAENSQKGTTLTRVSATDADKGRNGEVSYSVSSTMDSVSDIFTVDEK 270 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 G + + +DF++ + Y + + A DSGG SD++ V +++ D N+ AP+ + ++ E Sbjct: 271 GDVILLGAIDFEKAKYYQIDIEARDSGGLSDSSKVIVDVIDINDNAPLISILTKSDNIPE 330 Query: 481 DAPIGTTVLVVSATDSDVGINAQ-----------ITYSLSSEISNEAVAHHDQQFVINPQ 529 ++P T +++ S +D D N Q IT ++ +I++ A + + VI Sbjct: 331 NSPPNTVIVMFSVSDPDSSNNGQMILENPMELFRITIEIT-DINDNAPSFASNEKVIEIS 389 Query: 530 TGAITTNKL-----LDRETMSGYLLTVTAR--DGGVPSLSDTTDVEISVVDVNDNEPVFK 582 A+T +K LD + + L + + + D + D + DVNDN PVF+ Sbjct: 390 ESAVTGSKFVLEKALDADIGTNGLQSYSLKPTDNFALKYENQADGGKRISDVNDNAPVFE 449 Query: 583 QQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE---EGSFV-IDPASGV 638 + Y A I+E+ G S+ V A DAD N R+ Y L+ S+V + SGV Sbjct: 450 RSSYQAYIVENNTPGLSIFTVRARDADWNQNARVSYILEESSVNGVPVSSYVSVSADSGV 509 Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF------ESDCL 692 + ++ D E + A DGG+PP SS V V I I+D ND+PP + Sbjct: 510 VHAVRSFDYEQIKDFQFLVRAQDGGSPPLSSNVSVRILIQDQNDNPPQVLYPVQTGGSMV 569 Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752 + ++ +G + ++ A D D G NA + Y ++ D F + + G + V V Sbjct: 570 AEMVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLQKATDRALFEVGLQNG--EIRTVRQV 627 Query: 753 DLDYESPRKKYELVIRAASPPLWN-DVRVEILVTD 786 D ++ +++ +++ P + V V + V D Sbjct: 628 S-DKDAVKQRLSVIVEDNGQPSRSATVIVNVAVAD 661 Score = 178 bits (433), Expect = 2e-42 Identities = 159/620 (25%), Positives = 263/620 (42%), Gaps = 50/620 (8%) Query: 97 GALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT 156 G LL + +DRE + + T Q + + I V I D NDN P F + Sbjct: 55 GVLLVKDRIDREMLCKQTTPCALHLQI--ILENPMELFRITVEITDINDNSPVFKYEEKL 112 Query: 157 VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN---TQMQFSIDSLSG-DVSLV 212 + E S +A DAD+G N Y++ + +MQ D + ++ L Sbjct: 113 FEISE--SAVPGSKFVLDRAVDADIGVNGLKNYSLKPSDHFQLRMQHHTDGNNKVEMVLH 170 Query: 213 KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI 272 K LD E+ L++ A DGG P S T ++ + + DVNDNAP F +++ +++EN Sbjct: 171 KQLDREKEEEMSLLLTAVDGGEPQMSGTVKIFVTVLDVNDNAPVFVQPVYKAAIAENSQK 230 Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332 G ++ RV A DAD+G N E++Y+++ +V T+D + G V G +D E Y Sbjct: 231 GTTLTRVSATDADKGRNGEVSYSVSST--MDSVSDIFTVDEK-GDVILLGAIDFEKAKYY 287 Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392 Q+ + A D G S+ + + E+ PP T +V + +D Sbjct: 288 QIDIEARDSGGLSDSSKVIVDVIDINDNAPLISILTKSDNI--PENSPPNTVIVMFSVSD 345 Query: 393 ADEDNRLHYEITGGNTRGRFSI----TSQNGRGLITVAQPLDFKQE----RRYVLTVSAT 444 D N + R +I + N + + ++ + ++VL + Sbjct: 346 PDSSNNGQMILENPMELFRITIEITDINDNAPSFASNEKVIEISESAVTGSKFVLEKALD 405 Query: 445 DSGGRSDTAMVQINITD------------ANNYAPVFENAP------YTASVFEDAPIGT 486 G + + TD + V +NAP Y A + E+ G Sbjct: 406 ADIGTNGLQSYSLKPTDNFALKYENQADGGKRISDVNDNAPVFERSSYQAYIVENNTPGL 465 Query: 487 TVLVVSATDSDVGINAQITYSL-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 ++ V A D+D NA+++Y L S ++ V+ + ++ +G + + D E + Sbjct: 466 SIFTVRARDADWNQNARVSYILEESSVNGVPVSSY---VSVSADSGVVHAVRSFDYEQIK 522 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM------EDALVGTS 599 + V A+DGG P LS V I + D NDN P + T M A VG Sbjct: 523 DFQFLVRAQDGGSPPLSSNVSVRILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYL 582 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 V++V A D D G N + Y+L K + F + +G IRT + + + L + Sbjct: 583 VTKVVAVDVDSGQNAWLSYKLQ-KATDRALFEVGLQNGEIRTVRQVSDKDAVKQRLSVIV 641 Query: 660 IDGGTPPQSSTVIVHIKIED 679 D G P +S+TVIV++ + D Sbjct: 642 EDNGQPSRSATVIVNVAVAD 661 Score = 144 bits (350), Expect = 2e-32 Identities = 132/453 (29%), Positives = 215/453 (47%), Gaps = 44/453 (9%) Query: 374 ELAEDEPPGTPVVTLTATDADED-NRL-HYEIT-GGNTRGRFSI-TSQNGRGLITVAQPL 429 E++E PG+ V A DAD N L +Y + + + R T N + + + + L Sbjct: 114 EISESAVPGSKFVLDRAVDADIGVNGLKNYSLKPSDHFQLRMQHHTDGNNKVEMVLHKQL 173 Query: 430 DFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 D ++E L ++A D G S T + + + D N+ APVF Y A++ E++ GTT Sbjct: 174 DREKEEEMSLLLTAVDGGEPQMSGTVKIFVTVLDVNDNAPVFVQPVYKAAIAENSQKGTT 233 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 + VSATD+D G N +++YS+SS + + + F ++ + G + +D E Y Sbjct: 234 LTRVSATDADKGRNGEVSYSVSSTMDSVS-----DIFTVD-EKGDVILLGAIDFEKAKYY 287 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 + + ARD G LSD++ V + V+D+NDN P+ + NI E++ T + +D Sbjct: 288 QIDIEARDSG--GLSDSSKVIVDVIDINDNAPLISILTKSDNIPENSPPNTVIVMFSVSD 345 Query: 608 ADVGLNG-----------RIHYELDPKDREEGSF-----VIDPASGVIRTNK-----ALD 646 D NG RI E+ + SF VI+ + + +K ALD Sbjct: 346 PDSSNNGQMILENPMELFRITIEITDINDNAPSFASNEKVIEISESAVTGSKFVLEKALD 405 Query: 647 RESVATHDLKAVAI---DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIG 703 + + T+ L++ ++ D + +I D+ND+ PVFE YI EN+ G Sbjct: 406 AD-IGTNGLQSYSLKPTDNFALKYENQADGGKRISDVNDNAPVFERSSYQAYIVENNTPG 464 Query: 704 TTIGEIRAHDPDEGPNAVVHYSIKGGDDSN-SFSLETRQGSDKAELVTMVDLDYESPRKK 762 +I +RA D D NA V Y ++ + S +D + + DYE K Sbjct: 465 LSIFTVRARDADWNQNARVSYILEESSVNGVPVSSYVSVSADSGVVHAVRSFDYEQI-KD 523 Query: 763 YELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792 ++ ++RA SPPL ++V V IL+ D NDN P Sbjct: 524 FQFLVRAQDGGSPPLSSNVSVRILIQDQNDNPP 556 Score = 137 bits (332), Expect = 4e-30 Identities = 89/269 (33%), Positives = 129/269 (47%), Gaps = 6/269 (2%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 V + ITD N+ AP FE + + E A +G ++ A D D G N+ Y L Sbjct: 1293 VTVEITDINDNAPFFEKSEIRFKISESAVVGAKFVLQRAVDLDAGTNSLQGYVLKPSDHF 1352 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 H+ N + + K LDRE L +TA DGG P +S T + ++V+D Sbjct: 1353 ILKLHNQPDGTKNIE---MVLQKPLDREENEFISLALTAVDGGEPQMSGTMQILVTVLDA 1409 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFVID 633 NDN PVF Q +Y +I E+A GT V+ V A+D D LN +I Y + + D F ++ Sbjct: 1410 NDNAPVFTQPVYKGSIAENAAKGTIVTSVSASDNDHDLNSKITYSITNTLDDVRRLFEVN 1469 Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693 +G +R LD E + + A+D G S VIV + D+ND+ P+ + + Sbjct: 1470 EDNGEVRLTGHLDYEKKRNYQINVQAVDHGGLTDSCKVIV--DVIDVNDNKPMIKIMSKS 1527 Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVV 722 ISEN+ T + I DPD G N V Sbjct: 1528 AIISENATPETVVTMINIQDPDSGENGRV 1556 Score = 135 bits (327), Expect = 1e-29 Identities = 141/493 (28%), Positives = 213/493 (43%), Gaps = 64/493 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND++PVF Y+A++ E + GTT+ + ATD D G+N EV Y++ T D+ Sbjct: 203 VTVLDVNDNAPVFVQPVYKAAIAENSQKGTTLTRVSATDADKGRNGEVSYSVSS-TMDS- 260 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 V D+F +D + +L A +D EK Y + ++A D S L Sbjct: 261 ---------------VSDIFTVDEKGDVILLGA-IDFEKAKYYQIDIEARD-----SGGL 299 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS----- 185 S ++ + V++ID NDN P S T + ++ E+ N VI +D D N Sbjct: 300 SDSSKVIVDVIDINDNAPLISILTKSDNIPENSP--PNTVIVMFSVSDPDSSNNGQMILE 357 Query: 186 --------AIRYAIIGGNTQ--------MQFSIDSLSGD-VSLVKTLDYE----QVRSYR 224 I I N ++ S +++G L K LD + ++SY Sbjct: 358 NPMELFRITIEITDINDNAPSFASNEKVIEISESAVTGSKFVLEKALDADIGTNGLQSYS 417 Query: 225 LVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA 284 L + D + N I DVNDNAP F S +Q + EN G SI V+A DA Sbjct: 418 L--KPTDNFALKYENQADGGKRISDVNDNAPVFERSSYQAYIVENNTPGLSIFTVRARDA 475 Query: 285 DEGVNAELTYTMTDKDYTG-NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD 343 D NA ++Y + + G V +++ SG V+ D E +Q LV A DGG Sbjct: 476 DWNQNARVSYILEESSVNGVPVSSYVSVSADSGVVHAVRSFDYEQIKDFQFLVRAQDGGS 535 Query: 344 PPRSATATXXXXXXXXXXXXXXFM-PGQYEVELAEDEPP-----GTPVVTLTATDADEDN 397 PP S+ + + P Q + + P G V + A D D Sbjct: 536 PPLSSNVSVRILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQ 595 Query: 398 R--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMV 455 L Y++ R F + QNG + TV Q D K + L+V D+G S +A V Sbjct: 596 NAWLSYKLQKATDRALFEVGLQNGE-IRTVRQVSD-KDAVKQRLSVIVEDNGQPSRSATV 653 Query: 456 QINITDANNYAPV 468 +N+ A+++ V Sbjct: 654 IVNVAVADSFPEV 666 Score = 126 bits (303), Expect = 1e-26 Identities = 80/232 (34%), Positives = 121/232 (52%), Gaps = 8/232 (3%) Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE 626 + + + D+NDN PVFK + I E A+ G+ A DAD+G+NG +Y L P D Sbjct: 92 ITVEITDINDNSPVFKYEEKLFEISESAVPGSKFVLDRAVDADIGVNGLKNYSLKPSDHF 151 Query: 627 EGSFV--IDPASGV-IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS 683 + D + V + +K LDRE L A+DGG P S TV + + + D+ND+ Sbjct: 152 QLRMQHHTDGNNKVEMVLHKQLDREKEEEMSLLLTAVDGGEPQMSGTVKIFVTVLDVNDN 211 Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 PVF I+ENS GTT+ + A D D+G N V YS+ DS S + Sbjct: 212 APVFVQPVYKAAIAENSQKGTTLTRVSATDADKGRNGEVSYSVSSTMDSVS---DIFTVD 268 Query: 744 DKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAPVM 794 +K +++ + +D+E K Y++ I A S L + +V + V D+NDNAP++ Sbjct: 269 EKGDVILLGAIDFEK-AKYYQIDIEARDSGGLSDSSKVIVDVIDINDNAPLI 319 Score = 118 bits (284), Expect = 2e-24 Identities = 79/285 (27%), Positives = 138/285 (48%), Gaps = 27/285 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND+SPVF+ ++ + E A G+ + +A D DIG N Y +L Sbjct: 94 VEITDINDNSPVFKYEEKLFEISESAVPGSKFVLDRAVDADIGVNGLKNY--------SL 145 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGA-LLTRASLDREKVARYTVLVKATDQASPVSDR 129 P D ++ DG + ++ LDREK ++L+ A D P + Sbjct: 146 KPSD--------HFQLRMQHHTDGNNKVEMVLHKQLDREKEEEMSLLLTAVDGGEP---Q 194 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 +S T I V ++D NDN P F + Y ++ E+ + ++ ATDAD G N + Y Sbjct: 195 MSGTVKIFVTVLDVNDNAPVFVQPVYKAAIAENSQ--KGTTLTRVSATDADKGRNGEVSY 252 Query: 190 AIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 ++ + F++D GDV L+ +D+E+ + Y++ I A+D G S+++++++++ Sbjct: 253 SVSSTMDSVSDIFTVDE-KGDVILLGAIDFEKAKYYQIDIEARDSG--GLSDSSKVIVDV 309 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292 D+NDNAP +++ EN P IV D D N ++ Sbjct: 310 IDINDNAPLISILTKSDNIPENSPPNTVIVMFSVSDPDSSNNGQM 354 Score = 117 bits (282), Expect = 4e-24 Identities = 100/350 (28%), Positives = 154/350 (44%), Gaps = 13/350 (3%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ-ITYSLSS-EI 512 V + ITD N+ AP F+NA + A + +V A S VG AQ + + ++ Sbjct: 1177 VTVEITDINDNAPNFKNAEKRFEIIS-AQVSYSVPEEMAKGSLVGNIAQDLGLDVKRFKV 1235 Query: 513 SNEAVAHHDQ-QFV-INPQTGAITTNKLLDRETMSGYLLTVTARDGGV-PSLSDTTDVEI 569 N V D +++ ++ G + + +DRE + G + V + + V + Sbjct: 1236 GNARVYSGDSMEYIELDRDRGVLLIKERIDREALCGEVTPCAVHFQIVLENPMEFYSVTV 1295 Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629 + D+NDN P F++ I E A+VG A D D G N Y L P D Sbjct: 1296 EITDINDNAPFFEKSEIRFKISESAVVGAKFVLQRAVDLDAGTNSLQGYVLKPSDHFILK 1355 Query: 630 FVIDPASGV---IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPV 686 P + K LDRE L A+DGG P S T+ + + + D ND+ PV Sbjct: 1356 LHNQPDGTKNIEMVLQKPLDREENEFISLALTAVDGGEPQMSGTMQILVTVLDANDNAPV 1415 Query: 687 FESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746 F I+EN+ GT + + A D D N+ + YSI D E + D Sbjct: 1416 FTQPVYKGSIAENAAKGTIVTSVSASDNDHDLNSKITYSITNTLDDVRRLFEVNE--DNG 1473 Query: 747 ELVTMVDLDYESPRKKYELVIRAAS-PPLWNDVRVEILVTDVNDNAPVMK 795 E+ LDYE ++ Y++ ++A L + +V + V DVNDN P++K Sbjct: 1474 EVRLTGHLDYEK-KRNYQINVQAVDHGGLTDSCKVIVDVIDVNDNKPMIK 1522 Score = 116 bits (279), Expect = 9e-24 Identities = 77/273 (28%), Positives = 130/273 (47%), Gaps = 8/273 (2%) Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + I D+NDNAP F S + +SE+ +G V +A D D G N+ Y + D+ Sbjct: 1295 VEITDINDNAPFFEKSEIRFKISESAVVGAKFVLQRAVDLDAGTNSLQGYVLKPSDHF-I 1353 Query: 305 VDLPITID-PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 + L D ++ + LDRE L +TA DGG+P S T Sbjct: 1354 LKLHNQPDGTKNIEMVLQKPLDREENEFISLALTAVDGGEPQMSGTMQILVTVLDANDNA 1413 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITG--GNTRGRFSITSQNG 419 F Y+ +AE+ GT V +++A+D D D +++ Y IT + R F + NG Sbjct: 1414 PVFTQPVYKGSIAENAAKGTIVTSVSASDNDHDLNSKITYSITNTLDDVRRLFEVNEDNG 1473 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVF 479 + + LD++++R Y + V A D GG +D+ V +++ D N+ P+ + +A + Sbjct: 1474 E--VRLTGHLDYEKKRNYQINVQAVDHGGLTDSCKVIVDVIDVNDNKPMIKIMSKSAIIS 1531 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512 E+A T V +++ D D G N ++ ++ I Sbjct: 1532 ENATPETVVTMINIQDPDSGENGRVQCFITENI 1564 Score = 110 bits (265), Expect = 5e-22 Identities = 67/196 (34%), Positives = 105/196 (53%), Gaps = 9/196 (4%) Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480 + + +PLD ++ L ++A D G S T + + + DAN+ APVF Y S+ E Sbjct: 1368 MVLQKPLDREENEFISLALTAVDGGEPQMSGTMQILVTVLDANDNAPVFTQPVYKGSIAE 1427 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 +A GT V VSA+D+D +N++ITYS+++ + + + F +N G + LD Sbjct: 1428 NAAKGTIVTSVSASDNDHDLNSKITYSITNTLDDVR-----RLFEVNEDNGEVRLTGHLD 1482 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 E Y + V A D G L+D+ V + V+DVNDN+P+ K +A I E+A T V Sbjct: 1483 YEKKRNYQINVQAVDHG--GLTDSCKVIVDVIDVNDNKPMIKIMSKSAIISENATPETVV 1540 Query: 601 SQVGATDADVGLNGRI 616 + + D D G NGR+ Sbjct: 1541 TMINIQDPDSGENGRV 1556 Score = 108 bits (259), Expect = 2e-21 Identities = 70/230 (30%), Positives = 112/230 (48%), Gaps = 11/230 (4%) Query: 457 INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL-SSEISNE 515 + I+D N+ APVFE + Y A + E+ G ++ V A D+D NA+++Y L S ++ Sbjct: 800 LEISDVNDNAPVFERSSYQAYIVENNSPGLSIFTVRARDADWSQNARVSYILEESSVNGV 859 Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575 V+ + ++ +G + + D E + + V A+DGG P LS V I + D N Sbjct: 860 PVSSY---VSVSADSGVVHAVRSFDYEQIKDFHFLVRAQDGGSPPLSSNVSVRILIQDQN 916 Query: 576 DNEPVFKQQLYTANIM------EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629 DN P + T M A VG V++V A D D G N + Y+L K + Sbjct: 917 DNPPQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLQ-KATDRAL 975 Query: 630 FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679 F + +G IRT + + + L + D G P +S+TVIV++ + D Sbjct: 976 FEVGLQNGEIRTVRQVSDKDAVKQRLSVIVEDNGQPSRSATVIVNVAVAD 1025 Score = 105 bits (252), Expect = 2e-20 Identities = 71/223 (31%), Positives = 110/223 (49%), Gaps = 17/223 (7%) Query: 138 VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY-----AII 192 + I D NDN P F +Y + E+ S I ++A DAD N+ + Y ++ Sbjct: 800 LEISDVNDNAPVFERSSYQAYIVENNS--PGLSIFTVRARDADWSQNARVSYILEESSVN 857 Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252 G S+ + SG V V++ DYEQ++ + ++RAQDGGSP S+ + I I+D ND Sbjct: 858 GVPVSSYVSVSADSGVVHAVRSFDYEQIKDFHFLVRAQDGGSPPLSSNVSVRILIQDQND 917 Query: 253 NAPR-FYT-----SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 N P+ Y S+ E V + +GY + +V A D D G NA L+Y + + Sbjct: 918 NPPQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLQKATDRALFE 977 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT 349 + + ++G + T Q+ + K +L V D G P RSAT Sbjct: 978 VGL----QNGEIRTVRQVSDKDAVKQRLSVIVEDNGQPSRSAT 1016 Score = 103 bits (248), Expect = 5e-20 Identities = 75/259 (28%), Positives = 118/259 (45%), Gaps = 10/259 (3%) Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 + +D G LL + +DRE + Q V + ++ V I D NDN Sbjct: 1247 EYIELDRDRGVLLIKERIDREALCGEVTPCAVHFQI--VLENPMEFYSVTVEITDINDNA 1304 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGN---TQMQFSIDS 204 P F + + E V V+ + A D D G NS Y + + ++ D Sbjct: 1305 PFFEKSEIRFKISESAVVGAKFVLQR--AVDLDAGTNSLQGYVLKPSDHFILKLHNQPDG 1362 Query: 205 LSG-DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263 ++ L K LD E+ L + A DGG P S T Q+L+ + D NDNAP F +++ Sbjct: 1363 TKNIEMVLQKPLDREENEFISLALTAVDGGEPQMSGTMQILVTVLDANDNAPVFTQPVYK 1422 Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323 S++EN G + V A D D +N+++TY++T+ +V ++ +G V +G Sbjct: 1423 GSIAENAAKGTIVTSVSASDNDHDLNSKITYSITNT--LDDVRRLFEVNEDNGEVRLTGH 1480 Query: 324 LDRETQAKYQLLVTATDGG 342 LD E + YQ+ V A D G Sbjct: 1481 LDYEKKRNYQINVQAVDHG 1499 Score = 102 bits (244), Expect = 2e-19 Identities = 75/291 (25%), Positives = 133/291 (45%), Gaps = 26/291 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND++P FE + + E A G + +A D D G N+ Y L Sbjct: 1295 VEITDINDNAPFFEKSEIRFKISESAVVGAKFVLQRAVDLDAGTNSLQGYV--------L 1346 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGA-LLTRASLDREKVARYTVLVKATDQASPVSDR 129 P D + DG ++ + LDRE+ ++ + A D P + Sbjct: 1347 KPSDHFILKLHN--------QPDGTKNIEMVLQKPLDREENEFISLALTAVDGGEP---Q 1395 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 +S T I V ++D NDN P F++ Y S+ E+ + ++ + A+D D NS I Y Sbjct: 1396 MSGTMQILVTVLDANDNAPVFTQPVYKGSIAENAA--KGTIVTSVSASDNDHDLNSKITY 1453 Query: 190 AIIG--GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 +I + + F ++ +G+V L LDYE+ R+Y++ ++A D G +++ ++++++ Sbjct: 1454 SITNTLDDVRRLFEVNEDNGEVRLTGHLDYEKKRNYQINVQAVDHGG--LTDSCKVIVDV 1511 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 DVNDN P +SEN + + D D G N + +T+ Sbjct: 1512 IDVNDNKPMIKIMSKSAIISENATPETVVTMINIQDPDSGENGRVQCFITE 1562 Score = 95.1 bits (226), Expect = 2e-17 Identities = 69/238 (28%), Positives = 112/238 (47%), Gaps = 14/238 (5%) Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619 S+ D D + + DVNDN PVF++ Y A I+E+ G S+ V A DAD N R+ Y Sbjct: 791 SILDEPDSPLEISDVNDNAPVFERSSYQAYIVENNSPGLSIFTVRARDADWSQNARVSYI 850 Query: 620 LDPKDRE---EGSFV-IDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675 L+ S+V + SGV+ ++ D E + A DGG+PP SS V V I Sbjct: 851 LEESSVNGVPVSSYVSVSADSGVVHAVRSFDYEQIKDFHFLVRAQDGGSPPLSSNVSVRI 910 Query: 676 KIEDINDSPPVF------ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG 729 I+D ND+PP + + ++ +G + ++ A D D G NA + Y ++ Sbjct: 911 LIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLQKA 970 Query: 730 DDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN-DVRVEILVTD 786 D F + + G + V V D ++ +++ +++ P + V V + V D Sbjct: 971 TDRALFEVGLQNG--EIRTVRQVS-DKDAVKQRLSVIVEDNGQPSRSATVIVNVAVAD 1025 Score = 95.1 bits (226), Expect = 2e-17 Identities = 67/243 (27%), Positives = 113/243 (46%), Gaps = 21/243 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND++PVFE Y+A + E S G ++ T++A D D +NA V Y +E + + + Sbjct: 800 LEISDVNDNAPVFERSSYQAYIVENNSPGLSIFTVRARDADWSQNARVSYILEESSVNGV 859 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 V + SG + S D E++ + LV+A D SP L Sbjct: 860 P--------------VSSYVSVSADSGVVHAVRSFDYEQIKDFHFLVRAQDGGSPP---L 902 Query: 131 SSTATIHVNIIDDNDNYPQ--FSEKTYTVSVDEDI--SVTDNPVIAKIKATDADVGANSA 186 SS ++ + I D NDN PQ + +T V E + S ++ K+ A D D G N+ Sbjct: 903 SSNVSVRILIQDQNDNPPQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQNAW 962 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 + Y + + F + +G++ V+ + + RL + +D G PSRS T + + Sbjct: 963 LSYKLQKATDRALFEVGLQNGEIRTVRQVSDKDAVKQRLSVIVEDNGQPSRSATVIVNVA 1022 Query: 247 IRD 249 + D Sbjct: 1023 VAD 1025 Score = 84.2 bits (199), Expect = 5e-14 Identities = 70/233 (30%), Positives = 102/233 (43%), Gaps = 11/233 (4%) Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG- 303 + I DVNDNAP F S +Q + EN G SI V+A DAD NA ++Y + + G Sbjct: 800 LEISDVNDNAPVFERSSYQAYIVENNSPGLSIFTVRARDADWSQNARVSYILEESSVNGV 859 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXX 363 V +++ SG V+ D E + LV A DGG PP S+ + Sbjct: 860 PVSSYVSVSADSGVVHAVRSFDYEQIKDFHFLVRAQDGGSPPLSSNVSVRILIQDQNDNP 919 Query: 364 XXFM-PGQYEVELAEDEPP-----GTPVVTLTATDADEDNR--LHYEITGGNTRGRFSIT 415 + P Q + + P G V + A D D L Y++ R F + Sbjct: 920 PQVLYPVQTGGSMVAEMVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLQKATDRALFEVG 979 Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPV 468 QNG + TV Q D K + L+V D+G S +A V +N+ A+++ V Sbjct: 980 LQNGE-IRTVRQVSD-KDAVKQRLSVIVEDNGQPSRSATVIVNVAVADSFPEV 1030 Score = 68.5 bits (160), Expect = 2e-09 Identities = 43/122 (35%), Positives = 62/122 (50%), Gaps = 5/122 (4%) Query: 675 IKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN- 733 ++I D+ND+ PVFE YI EN+ G +I +RA D D NA V Y ++ + Sbjct: 800 LEISDVNDNAPVFERSSYQAYIVENNSPGLSIFTVRARDADWSQNARVSYILEESSVNGV 859 Query: 734 SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDN 790 S +D + + DYE K + ++RA SPPL ++V V IL+ D NDN Sbjct: 860 PVSSYVSVSADSGVVHAVRSFDYEQI-KDFHFLVRAQDGGSPPLSSNVSVRILIQDQNDN 918 Query: 791 AP 792 P Sbjct: 919 PP 920 Score = 37.9 bits (84), Expect = 4.0 Identities = 27/100 (27%), Positives = 47/100 (47%), Gaps = 6/100 (6%) Query: 779 RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNN 836 R+ + +TD+NDN+PV K + +F + P F A DAD V Y + ++ Sbjct: 91 RITVEITDINDNSPVFKYEEKLFEISESAVPGSKFVLDRAVDADIGVNGLKNYSLKPSDH 150 Query: 837 ANLILLNETTGS----MTLSPQLNTNVPKLATMEVSVTDG 872 L + + T G+ M L QL+ + ++ ++ DG Sbjct: 151 FQLRMQHHTDGNNKVEMVLHKQLDREKEEEMSLLLTAVDG 190 >UniRef50_Q4RRF3 Cluster: Chromosome 16 SCAF15002, whole genome shotgun sequence; n=5; Clupeocephala|Rep: Chromosome 16 SCAF15002, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 421 Score = 191 bits (465), Expect = 3e-46 Identities = 140/421 (33%), Positives = 211/421 (50%), Gaps = 27/421 (6%) Query: 176 ATDADVGANSAIRYAIIGGNTQMQFSIDSLSG-------DVSLVKTLDYEQVRSYRLVIR 228 A DAD G + Y I GN F++++ G D+ + LD E+ +Y L + Sbjct: 11 AVDADQGQLTTQGYLIKDGNVGQAFTLETRRGSNGVLYLDLVVNTILDREKRSTYTLSLE 70 Query: 229 AQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV 288 A DGGSP R++ L I ++D+NDNAP F S + +SEN+ G +I++V A D DEG Sbjct: 71 AFDGGSPKRTDVMSLDITVQDINDNAPVFNQSRYHAIISENLQPGSNILQVFATDDDEGD 130 Query: 289 NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA 348 N ++ Y + + + D ID +SG + + LD E + ++L+V A D P + Sbjct: 131 NGKVLYEINRRQ--SDPDRYFVIDSQSGVITLNKPLDFEMKRVHELVVQAQDNATQPEVS 188 Query: 349 TATXXXXXXXXX----XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYE 402 A F+ ++E PG V ++ TD D E ++ Sbjct: 189 NAFVTIHVRDYNDNQPTMTIIFLSEDGSPRVSEGAQPGQYVARISVTDPDYGEYANVNVS 248 Query: 403 ITGGNTRGRFSITSQ-NGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQIN 458 + GG+ G+F++T++ N LI V + LD ++ Y L V ATDSG R++++ + I Sbjct: 249 LEGGD--GKFALTTKDNIIYLICVDRILDREERDTYELRVMATDSGTPPLRAESSFI-IQ 305 Query: 459 ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518 +TD N+ P+F+ Y + E G+ VL V+A D D G N ITYSL + Sbjct: 306 VTDVNDNPPLFDQPVYRQVIPEVVFPGSFVLQVTARDKDHGPNGDITYSLFQD-----QG 360 Query: 519 HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578 H + F I+ TG ITT+ LD E +TV A DGG P +S T V I + D+NDNE Sbjct: 361 AHSKWFSIDSVTGIITTDSQLDYEKNPNPSITVVATDGGKPPMSSTALVNIVLQDINDNE 420 Query: 579 P 579 P Sbjct: 421 P 421 Score = 187 bits (456), Expect = 3e-45 Identities = 144/423 (34%), Positives = 204/423 (48%), Gaps = 30/423 (7%) Query: 281 AYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR---SGWVY----TSGQLDRETQAKYQ 333 A DAD+G Y + D GNV T++ R +G +Y + LDRE ++ Y Sbjct: 11 AVDADQGQLTTQGYLIKD----GNVGQAFTLETRRGSNGVLYLDLVVNTILDREKRSTYT 66 Query: 334 LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393 L + A DGG P R+ + F +Y ++E+ PG+ ++ + ATD Sbjct: 67 LSLEAFDGGSPKRTDVMSLDITVQDINDNAPVFNQSRYHAIISENLQPGSNILQVFATDD 126 Query: 394 DE-DN-RLHYEITG--GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR 449 DE DN ++ YEI + F I SQ+G +IT+ +PLDF+ +R + L V A D+ + Sbjct: 127 DEGDNGKVLYEINRRQSDPDRYFVIDSQSG--VITLNKPLDFEMKRVHELVVQAQDNATQ 184 Query: 450 SDT--AMVQINITDANNYAP----VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503 + A V I++ D N+ P +F + + V E A G V +S TD D G A Sbjct: 185 PEVSNAFVTIHVRDYNDNQPTMTIIFLSEDGSPRVSEGAQPGQYVARISVTDPDYGEYAN 244 Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD 563 + SL A+ D + I +++LDRE Y L V A D G P L Sbjct: 245 VNVSLEGGDGKFALTTKDNIIYL------ICVDRILDREERDTYELRVMATDSGTPPLRA 298 Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DP 622 + I V DVNDN P+F Q +Y I E G+ V QV A D D G NG I Y L Sbjct: 299 ESSFIIQVTDVNDNPPLFDQPVYRQVIPEVVFPGSFVLQVTARDKDHGPNGDITYSLFQD 358 Query: 623 KDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND 682 + F ID +G+I T+ LD E + VA DGG PP SST +V+I ++DIND Sbjct: 359 QGAHSKWFSIDSVTGIITTDSQLDYEKNPNPSITVVATDGGKPPMSSTALVNIVLQDIND 418 Query: 683 SPP 685 + P Sbjct: 419 NEP 421 Score = 182 bits (442), Expect = 2e-43 Identities = 133/428 (31%), Positives = 206/428 (48%), Gaps = 26/428 (6%) Query: 382 GTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITSQNG-RGLI----TVAQPLDFKQE 434 GT A DAD+ Y I GN F++ ++ G G++ V LD ++ Sbjct: 3 GTRFPLEPAVDADQGQLTTQGYLIKDGNVGQAFTLETRRGSNGVLYLDLVVNTILDREKR 62 Query: 435 RRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492 Y L++ A D G R+D + I + D N+ APVF + Y A + E+ G+ +L V Sbjct: 63 STYTLSLEAFDGGSPKRTDVMSLDITVQDINDNAPVFNQSRYHAIISENLQPGSNILQVF 122 Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552 ATD D G N ++ Y ++ S+ D+ FVI+ Q+G IT NK LD E + L V Sbjct: 123 ATDDDEGDNGKVLYEINRRQSDP-----DRYFVIDSQSGVITLNKPLDFEMKRVHELVVQ 177 Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEP----VFKQQLYTANIMEDALVGTSVSQVGATDA 608 A+D V I V D NDN+P +F + + + E A G V+++ TD Sbjct: 178 AQDNATQPEVSNAFVTIHVRDYNDNQPTMTIIFLSEDGSPRVSEGAQPGQYVARISVTDP 237 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 D G ++ L+ D + D +I ++ LDRE T++L+ +A D GTPP Sbjct: 238 DYGEYANVNVSLEGGDGKFALTTKDNIIYLICVDRILDREERDTYELRVMATDSGTPPLR 297 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-- 726 + I++ D+ND+PP+F+ I E G+ + ++ A D D GPN + YS+ Sbjct: 298 AESSFIIQVTDVNDNPPLFDQPVYRQVIPEVVFPGSFVLQVTARDKDHGPNGDITYSLFQ 357 Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPRKKYELVIR-AASPPLWNDVRVEILV 784 G S FS+++ G + T LDYE +P +V PP+ + V I++ Sbjct: 358 DQGAHSKWFSIDSVTGI----ITTDSQLDYEKNPNPSITVVATDGGKPPMSSTALVNIVL 413 Query: 785 TDVNDNAP 792 D+NDN P Sbjct: 414 QDINDNEP 421 Score = 169 bits (411), Expect = 1e-39 Identities = 124/354 (35%), Positives = 178/354 (50%), Gaps = 20/354 (5%) Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592 + N +LDRE S Y L++ A DGG P +D ++I+V D+NDN PVF Q Y A I E Sbjct: 51 LVVNTILDREKRSTYTLSLEAFDGGSPKRTDVMSLDITVQDINDNAPVFNQSRYHAIISE 110 Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDRE-EGSFVIDPASGVIRTNKALDRESVA 651 + G+++ QV ATD D G NG++ YE++ + + + FVID SGVI NK LD E Sbjct: 111 NLQPGSNILQVFATDDDEGDNGKVLYEINRRQSDPDRYFVIDSQSGVITLNKPLDFEMKR 170 Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP----VFESDCLTFYISENSPIGTTIG 707 H+L A D T P+ S V I + D ND+ P +F S+ + +SE + G + Sbjct: 171 VHELVVQAQDNATQPEVSNAFVTIHVRDYNDNQPTMTIIFLSEDGSPRVSEGAQPGQYVA 230 Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 I DPD G A V+ S++GGD F+L T+ V + LD E R YEL + Sbjct: 231 RISVTDPDYGEYANVNVSLEGGD--GKFALTTKDNIIYLICVDRI-LDREE-RDTYELRV 286 Query: 768 RA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNY--KDCFPVGPFGRVPAYDAD 822 A +PPL + I VTDVNDN P+ Q ++ + FP +V A D D Sbjct: 287 MATDSGTPPLRAESSFIIQVTDVNDNPPLFD--QPVYRQVIPEVVFPGSFVLQVTARDKD 344 Query: 823 --VTDKLQYRIL--SGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 + Y + G ++ ++ TG +T QL+ ++ V TDG Sbjct: 345 HGPNGDITYSLFQDQGAHSKWFSIDSVTGIITTDSQLDYEKNPNPSITVVATDG 398 Score = 144 bits (350), Expect = 2e-32 Identities = 118/382 (30%), Positives = 177/382 (46%), Gaps = 24/382 (6%) Query: 99 LLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS 158 L+ LDREK + YT+ ++A D SP + + ++ + + D NDN P F++ Y Sbjct: 51 LVVNTILDREKRSTYTLSLEAFDGGSP---KRTDVMSLDITVQDINDNAPVFNQSRYHAI 107 Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAI--IGGNTQMQFSIDSLSGDVSLVKTLD 216 + E++ N I ++ ATD D G N + Y I + F IDS SG ++L K LD Sbjct: 108 ISENLQPGSN--ILQVFATDDDEGDNGKVLYEINRRQSDPDRYFVIDSQSGVITLNKPLD 165 Query: 217 YEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES----VSENVPI 272 +E R + LV++AQD + + + I++RD NDN P E VSE Sbjct: 166 FEMKRVHELVVQAQDNATQPEVSNAFVTIHVRDYNDNQPTMTIIFLSEDGSPRVSEGAQP 225 Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332 G + R+ D D G A + ++ D G L T D + LDRE + Y Sbjct: 226 GQYVARISVTDPDYGEYANVNVSLEGGD--GKFAL-TTKDNIIYLICVDRILDREERDTY 282 Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392 +L V ATD G PP A ++ F Y + E PG+ V+ +TA D Sbjct: 283 ELRVMATDSGTPPLRAESSFIIQVTDVNDNPPLFDQPVYRQVIPEVVFPGSFVLQVTARD 342 Query: 393 ADE--DNRLHYEI---TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447 D + + Y + G +++ FSI S G+IT LD+++ +TV ATD G Sbjct: 343 KDHGPNGDITYSLFQDQGAHSKW-FSIDSVT--GIITTDSQLDYEKNPNPSITVVATDGG 399 Query: 448 --GRSDTAMVQINITDANNYAP 467 S TA+V I + D N+ P Sbjct: 400 KPPMSSTALVNIVLQDINDNEP 421 Score = 143 bits (347), Expect = 5e-32 Identities = 104/343 (30%), Positives = 165/343 (48%), Gaps = 25/343 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND++PVF +Y A + E G+ +L + ATD D G N +V Y I +D Sbjct: 87 ITVQDINDNAPVFNQSRYHAIISENLQPGSNILQVFATDDDEGDNGKVLYEINRRQSD-- 144 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 P+ F ID +SG + LD E + ++V+A D A+ + Sbjct: 145 -PD--------------RYFVIDSQSGVITLNKPLDFEMKRVHELVVQAQDNATQ-PEVS 188 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP--VIAKIKATDADVGANSAIR 188 ++ TIHV D NDN P + + +S P +A+I TD D G + + Sbjct: 189 NAFVTIHVR--DYNDNQPTMTIIFLSEDGSPRVSEGAQPGQYVARISVTDPDYGEYANVN 246 Query: 189 YAIIGGNTQMQFSI-DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 ++ GG+ + + D++ + + + LD E+ +Y L + A D G+P + +I + Sbjct: 247 VSLEGGDGKFALTTKDNIIYLICVDRILDREERDTYELRVMATDSGTPPLRAESSFIIQV 306 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 DVNDN P F ++++ + E V G +++V A D D G N ++TY++ G Sbjct: 307 TDVNDNPPLFDQPVYRQVIPEVVFPGSFVLQVTARDKDHGPNGDITYSLFQDQ--GAHSK 364 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350 +ID +G + T QLD E + V ATDGG PP S+TA Sbjct: 365 WFSIDSVTGIITTDSQLDYEKNPNPSITVVATDGGKPPMSSTA 407 Score = 56.4 bits (130), Expect = 1e-05 Identities = 53/184 (28%), Positives = 84/184 (45%), Gaps = 11/184 (5%) Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA---ELVTMVDLDYES 758 IGT A D D+G Y IK G+ +F+LETR+GS+ +LV LD E Sbjct: 2 IGTRFPLEPAVDADQGQLTTQGYLIKDGNVGQAFTLETRRGSNGVLYLDLVVNTILDREK 61 Query: 759 PRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR 815 R Y L + A SP + + ++I V D+NDNAPV + ++ P + Sbjct: 62 -RSTYTLSLEAFDGGSPKRTDVMSLDITVQDINDNAPVFNQSRYHAIISENLQPGSNILQ 120 Query: 816 VPAYDADVTD--KLQYRI--LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 V A D D D K+ Y I + +++ +G +TL+ L+ + ++ + V D Sbjct: 121 VFATDDDEGDNGKVLYEINRRQSDPDRYFVIDSQSGVITLNKPLDFEMKRVHELVVQAQD 180 Query: 872 GVNE 875 + Sbjct: 181 NATQ 184 >UniRef50_Q9NPG4 Cluster: Protocadherin-12 precursor; n=16; Theria|Rep: Protocadherin-12 precursor - Homo sapiens (Human) Length = 1184 Score = 190 bits (463), Expect = 5e-46 Identities = 143/500 (28%), Positives = 235/500 (47%), Gaps = 23/500 (4%) Query: 198 MQFSIDSLSGDVSLVKTLDYEQV-RSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256 + +DS G +S + LD EQ+ R + + + D + + I + D+ND+ PR Sbjct: 75 LPIQVDSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPR 134 Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP-RS 315 F + +SE+ + I +A D D G N TYT++ ++ +D+ + D + Sbjct: 135 FPKGEQELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFA-LDVIVGPDETKH 193 Query: 316 GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375 + +LDRE + + L++TA D G+PP+S T+ F +E+ Sbjct: 194 AELIVVKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEI 253 Query: 376 AEDEPPGTPVVTLTATDADEDNRLHYEI-----TGGNTRGRFSITSQNGRGLITVAQPLD 430 ED PGT ++ LTATD D+ E FSI ++ G+ + + +PLD Sbjct: 254 QEDAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQ--VILRRPLD 311 Query: 431 FKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFEN--APYTASVFEDAPIGT 486 +++ Y + V A D G A V I + D N+ P A + V E P + Sbjct: 312 YEKNPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDS 371 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG 546 + +V A D D G N + LS E+ H + N T + TN LDRE Sbjct: 372 FIALVMADDLDSGHNGLVHCWLSQELG------HFRLKRTNGNTYMLLTNATLDREQWPK 425 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 Y LT+ A+D G+ LS + I + D+NDN PVF++ Y + E+ L + + A Sbjct: 426 YTLTLLAQDQGLQPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAH 485 Query: 607 DADVGLNGRIHYELDPKDREEGSFV-IDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 DAD+G+NG++ Y + +D V ID +G + ++L+ E +A + + +A D G P Sbjct: 486 DADLGINGKVSYRI--QDSPVAHLVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDSGQP 543 Query: 666 PQSSTVIVHIKIEDINDSPP 685 +S+V V + + D ND+ P Sbjct: 544 MLASSVSVWVSLLDANDNAP 563 Score = 173 bits (422), Expect = 4e-41 Identities = 141/503 (28%), Positives = 227/503 (45%), Gaps = 31/503 (6%) Query: 91 RIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNI--IDDNDNYP 148 ++D G L T LDRE++ R + D A IHV I +D ND+ P Sbjct: 78 QVDSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGD----LALIHVEIQVLDINDHQP 133 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG- 207 +F + + + E S+ I +A D D G N+ Y + + F++D + G Sbjct: 134 RFPKGEQELEISESASLRTR--IPLDRALDPDTGPNTLHTYTL---SPSEHFALDVIVGP 188 Query: 208 ------DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261 ++ +VK LD E + LV+ A D G+P +S T+ + +N+ D NDN+P F S Sbjct: 189 DETKHAELIVVKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESS 248 Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321 + E+ G ++++ A D D+G N E+ + ++ K V +ID ++G V Sbjct: 249 LALEIQEDAAPGTLLIKLTATDPDQGPNGEVEFFLS-KHMPPEVLDTFSIDAKTGQVILR 307 Query: 322 GQLDRETQAKYQLLVTATD-GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP 380 LD E Y++ V A D G +P + + + L + Sbjct: 308 RPLDYEKNPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEAL 367 Query: 381 PGTPVVTLT-ATDADEDNRLHYEITGGNTRGRFSITSQNGRG-LITVAQPLDFKQERRYV 438 P + L A D D + G F + NG ++ LD +Q +Y Sbjct: 368 PKDSFIALVMADDLDSGHNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYT 427 Query: 439 LTVSATDSGGRSDTAMVQ--INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496 LT+ A D G + +A Q I I+D N+ APVFE + Y S E+ ++ + A D+ Sbjct: 428 LTLLAQDQGLQPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDA 487 Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG 556 D+GIN +++Y I + VAH I+ TG +T + L+ E M+G+ V A D Sbjct: 488 DLGINGKVSY----RIQDSPVAH---LVAIDSNTGEVTAQRSLNYEEMAGFEFQVIAEDS 540 Query: 557 GVPSLSDTTDVEISVVDVNDNEP 579 G P L+ + V +S++D NDN P Sbjct: 541 GQPMLASSVSVWVSLLDANDNAP 563 Score = 164 bits (399), Expect = 3e-38 Identities = 140/500 (28%), Positives = 229/500 (45%), Gaps = 25/500 (5%) Query: 307 LPITIDPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 LPI +D G + T +LDRE + + + + D A Sbjct: 75 LPIQVDSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPR 134 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSIT---SQNGRG 421 F G+ E+E++E T + A D D N LH + + + Sbjct: 135 FPKGEQELEISESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHA 194 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVF 479 + V + LD + + L ++A D+G +S T++V++N+ D+N+ +P F + + Sbjct: 195 ELIVVKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQ 254 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 EDA GT ++ ++ATD D G N ++ + LS + E + F I+ +TG + + L Sbjct: 255 EDAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVL----DTFSIDAKTGQVILRRPL 310 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEP-VFKQQLYTANIMEDALVGT 598 D E Y + V ARD G + V I V+DVNDN P + +++ +AL Sbjct: 311 DYEKNPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKD 370 Query: 599 S-VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG---VIRTNKALDRESVATHD 654 S ++ V A D D G NG +H L +E G F + +G ++ TN LDRE + Sbjct: 371 SFIALVMADDLDSGHNGLVHCWLS---QELGHFRLKRTNGNTYMLLTNATLDREQWPKYT 427 Query: 655 LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 L +A D G P S+ + I+I DIND+ PVFE EN+ + I+AHD Sbjct: 428 LTLLAQDQGLQPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDA 487 Query: 715 DEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIR-AASP 772 D G N V Y I+ ++ ++++ G E+ L+YE +++++ + P Sbjct: 488 DLGINGKVSYRIQDSPVAHLVAIDSNTG----EVTAQRSLNYEEMAGFEFQVIAEDSGQP 543 Query: 773 PLWNDVRVEILVTDVNDNAP 792 L + V V + + D NDNAP Sbjct: 544 MLASSVSVWVSLLDANDNAP 563 Score = 163 bits (396), Expect = 6e-38 Identities = 141/497 (28%), Positives = 222/497 (44%), Gaps = 39/497 (7%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 IH +I VLD NDH P F + E + E AS T + +A D D G N YT Sbjct: 119 IHVEIQVLDINDHQPRFPKGEQELEISESASLRTRIPLDRALDPDTGPNTLHTYT----- 173 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 L+P + V + + L+ LDRE + + +++ A D +P Sbjct: 174 ---LSPSEHFALDVI-------VGPDETKHAELIVVKELDREIHSFFDLVLTAYDNGNPP 223 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 S T+ + VN++D NDN P F+E + + + ED ++ K+ ATD D G N Sbjct: 224 K---SGTSLVKVNVLDSNDNSPAFAESSLALEIQED--AAPGTLLIKLTATDPDQGPNGE 278 Query: 187 IRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQL 243 + + + + FSID+ +G V L + LDYE+ +Y + ++A+D G ++ Sbjct: 279 VEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPAYEVDVQARDLGPNPIPAHCKV 338 Query: 244 LINIRDVNDNAPRFYTSLFQES--VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 LI + DVNDN P + + + VSE +P I V A D D G N L + ++ Sbjct: 339 LIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIALVMADDLDSGHNG-LVHCWLSQE- 396 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 G+ L T + + + T+ LDRE KY L + A D G P SA Sbjct: 397 LGHFRLKRT-NGNTYMLLTNATLDREQWPKYTLTLLAQDQGLQPLSAKKQLSIQISDIND 455 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419 F +YEV E+ P ++T+ A DAD + ++ Y I +I S G Sbjct: 456 NAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSYRIQDSPVAHLVAIDSNTG 515 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTAS 477 +T + L++++ + V A DSG + + V +++ DAN+ AP Sbjct: 516 E--VTAQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWVSLLDANDNAP-----EVVQP 568 Query: 478 VFEDAPIGTTVLVVSAT 494 V D +VLV ++T Sbjct: 569 VLSDGKASLSVLVNAST 585 Score = 161 bits (390), Expect = 3e-37 Identities = 133/451 (29%), Positives = 208/451 (46%), Gaps = 25/451 (5%) Query: 421 GLITVAQPLDFKQE-RRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTAS 477 GL++ + LD +Q R++ + + D D A+ V+I + D N++ P F Sbjct: 84 GLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGEQELE 143 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT---GAIT 534 + E A + T + + A D D G N TY+LS H ++ P + Sbjct: 144 ISESASLRTRIPLDRALDPDTGPNTLHTYTLSPS------EHFALDVIVGPDETKHAELI 197 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 K LDRE S + L +TA D G P S T+ V+++V+D NDN P F + I EDA Sbjct: 198 VVKELDREIHSFFDLVLTAYDNGNPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDA 257 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREE--GSFVIDPASGVIRTNKALDRESVAT 652 GT + ++ ATD D G NG + + L E +F ID +G + + LD E Sbjct: 258 APGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTFSIDAKTGQVILRRPLDYEKNPA 317 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT--FYISENSPIGTTIGEIR 710 +++ A D G P + V IK+ D+ND+ P + +SE P + I + Sbjct: 318 YEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKDSFIALVM 377 Query: 711 AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770 A D D G N +VH + + F L+ G+ L+T LD E KY L + A Sbjct: 378 ADDLDSGHNGLVHCWLS--QELGHFRLKRTNGNTYM-LLTNATLDREQ-WPKYTLTLLAQ 433 Query: 771 SP---PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTD 825 PL ++ I ++D+NDNAPV + + + ++ P + A+DAD + Sbjct: 434 DQGLQPLSAKKQLSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGING 493 Query: 826 KLQYRILSGNNANLILLNETTGSMTLSPQLN 856 K+ YRI A+L+ ++ TG +T LN Sbjct: 494 KVSYRIQDSPVAHLVAIDSNTGEVTAQRSLN 524 Score = 100 bits (240), Expect = 5e-19 Identities = 62/195 (31%), Positives = 104/195 (53%), Gaps = 10/195 (5%) Query: 91 RIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQF 150 R +G + LLT A+LDRE+ +YT+ + A DQ LS+ + + I D NDN P F Sbjct: 404 RTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGL---QPLSAKKQLSIQISDINDNAPVF 460 Query: 151 SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVS 210 + Y VS E+ ++ +I IKA DAD+G N + Y I +IDS +G+V+ Sbjct: 461 EKSRYEVSTREN-NLPSLHLIT-IKAHDADLGINGKVSYRIQDSPVAHLVAIDSNTGEVT 518 Query: 211 LVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE-----S 265 ++L+YE++ + + A+D G P +++ + +++ D NDNAP + + S Sbjct: 519 AQRSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWVSLLDANDNAPEVVQPVLSDGKASLS 578 Query: 266 VSENVPIGYSIVRVQ 280 V N G+ +V ++ Sbjct: 579 VLVNASTGHLLVPIE 593 >UniRef50_Q6R0H9 Cluster: Cadherin-related neuronal receptor c01; n=4; Gallus gallus|Rep: Cadherin-related neuronal receptor c01 - Gallus gallus (Chicken) Length = 948 Score = 188 bits (458), Expect = 2e-45 Identities = 145/508 (28%), Positives = 241/508 (47%), Gaps = 30/508 (5%) Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLV-IRAQDGGSPSRS 238 + A SA ++ +I G+++ F+I++ +G +S+ + +D EQ+ + + + + Sbjct: 302 NAAALSARKFRMIIGSSKQYFNINATTGVLSVNEPIDREQLCELKSTCLLNYELVLENPL 361 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 ++ + DVNDN+P F S ++ SV E + G A D DEG N Y + Sbjct: 362 ELYRMEFKVLDVNDNSPSFPLSEYRVSVPEFLSPGARFALPNAQDLDEGTNGVQNYILNP 421 Query: 299 KDYTGNVDLPITIDPRSGWVYTS----GQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354 ++ ++++ + D G VY LDRE QA ++L++ A DGGDPPRS Sbjct: 422 DEHF-HLEMQMRGD---GSVYPELVLKKALDREQQATHRLVLIAEDGGDPPRSGDVPVIV 477 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI---TGGNTR 409 F Y + E+ P GT VV + ATD DE + + Y T + + Sbjct: 478 TVLDTNDNAPEFEQSVYRASVLENSPSGTLVVRVHATDLDEGPNGEVRYSFSNATAADLQ 537 Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAP 467 F I G +TV+ L ++ +L + A D G S TA + + ITD NN+ P Sbjct: 538 QMFLIHPHTGE--VTVSGDLAVQRPLLEML-IEARDKGAFALSSTAKLLVEITDVNNHGP 594 Query: 468 VFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527 A + + EDA GT + ++S D D G N ++T + + + + + Sbjct: 595 EITIASLSNPIPEDAVPGTVIALLSIVDKDPGENGKVTCQIPDNLPFQLKPSLENYY--- 651 Query: 528 PQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT 587 ++ T+ LLDRE +SGY +T+TA D G P ++ + + + DVNDN PVF + Sbjct: 652 ----SLITSGLLDRELISGYNITITATDLGSPPITTQQTLWVQISDVNDNPPVFAADTFD 707 Query: 588 ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG---SFV-IDPASGVIRTNK 643 + E+ +G + QV A+D D+G NG+I Y L SF+ + +G I + Sbjct: 708 VFVEENNPLGAFLYQVSASDLDIGENGQISYILRNSTVAGSALTSFLSVSLVNGSIYAKR 767 Query: 644 ALDRESVATHDLKAVAIDGGTPPQSSTV 671 A D E + + + A D G+P S+ + Sbjct: 768 AFDFEQLRSFHFQVEAKDNGSPALSAAM 795 Score = 184 bits (449), Expect = 2e-44 Identities = 145/482 (30%), Positives = 225/482 (46%), Gaps = 20/482 (4%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F I+ +G L +DRE++ + V + + ++D NDN P Sbjct: 322 FNINATTGVLSVNEPIDREQLCELKSTCLLNYEL--VLENPLELYRMEFKVLDVNDNSPS 379 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG---NTQMQFSID-SL 205 F Y VSV E +S A A D D G N Y + + +MQ D S+ Sbjct: 380 FPLSEYRVSVPEFLS--PGARFALPNAQDLDEGTNGVQNYILNPDEHFHLEMQMRGDGSV 437 Query: 206 SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES 265 ++ L K LD EQ ++RLV+ A+DGG P RS +++ + D NDNAP F S+++ S Sbjct: 438 YPELVLKKALDREQQATHRLVLIAEDGGDPPRSGDVPVIVTVLDTNDNAPEFEQSVYRAS 497 Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325 V EN P G +VRV A D DEG N E+ Y+ ++ ++ I P +G V SG L Sbjct: 498 VLENSPSGTLVVRVHATDLDEGPNGEVRYSFSNAT-AADLQQMFLIHPHTGEVTVSGDLA 556 Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 + + ++L+ A D G S+TA + ED PGT + Sbjct: 557 VQ-RPLLEMLIEARDKGAFALSSTAKLLVEITDVNNHGPEITIASLSNPIPEDAVPGTVI 615 Query: 386 VTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA 443 L+ D D E+ ++ +I N + + +N LIT + LD + Y +T++A Sbjct: 616 ALLSIVDKDPGENGKVTCQIP-DNLPFQLKPSLENYYSLIT-SGLLDRELISGYNITITA 673 Query: 444 TDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501 TD G T + + I+D N+ PVF + V E+ P+G + VSA+D D+G N Sbjct: 674 TDLGSPPITTQQTLWVQISDVNDNPPVFAADTFDVFVEENNPLGAFLYQVSASDLDIGEN 733 Query: 502 AQITYSL-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560 QI+Y L +S ++ A+ ++N G+I + D E + + V A+D G P+ Sbjct: 734 GQISYILRNSTVAGSALTSFLSVSLVN---GSIYAKRAFDFEQLRSFHFQVEAKDNGSPA 790 Query: 561 LS 562 LS Sbjct: 791 LS 792 Score = 167 bits (407), Expect = 3e-39 Identities = 116/377 (30%), Positives = 188/377 (49%), Gaps = 16/377 (4%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQ-NGRGLI 423 F +Y V + E PG A D DE N + I N F + Q G G + Sbjct: 380 FPLSEYRVSVPEFLSPGARFALPNAQDLDEGTNGVQNYIL--NPDEHFHLEMQMRGDGSV 437 Query: 424 ----TVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTAS 477 + + LD +Q+ + L + A D G RS V + + D N+ AP FE + Y AS Sbjct: 438 YPELVLKKALDREQQATHRLVLIAEDGGDPPRSGDVPVIVTVLDTNDNAPEFEQSVYRAS 497 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK 537 V E++P GT V+ V ATD D G N ++ YS S N A Q F+I+P TG +T + Sbjct: 498 VLENSPSGTLVVRVHATDLDEGPNGEVRYSFS----NATAADLQQMFLIHPHTGEVTVSG 553 Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG 597 L + +L + ARD G +LS T + + + DVN++ P + I EDA+ G Sbjct: 554 DLAVQRPLLEML-IEARDKGAFALSSTAKLLVEITDVNNHGPEITIASLSNPIPEDAVPG 612 Query: 598 TSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKA 657 T ++ + D D G NG++ ++ + ++ +I T+ LDRE ++ +++ Sbjct: 613 TVIALLSIVDKDPGENGKVTCQIPDNLPFQLKPSLENYYSLI-TSGLLDRELISGYNITI 671 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 A D G+PP ++ + ++I D+ND+PPVF +D ++ EN+P+G + ++ A D D G Sbjct: 672 TATDLGSPPITTQQTLWVQISDVNDNPPVFAADTFDVFVEENNPLGAFLYQVSASDLDIG 731 Query: 718 PNAVVHYSIKGGDDSNS 734 N + Y ++ + S Sbjct: 732 ENGQISYILRNSTVAGS 748 Score = 149 bits (362), Expect = 8e-34 Identities = 126/452 (27%), Positives = 202/452 (44%), Gaps = 45/452 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 + VLD ND+SP F + +Y SV E S G A D D G N Y Sbjct: 367 EFKVLDVNDNSPSFPLSEYRVSVPEFLSPGARFALPNAQDLDEGTNGVQNY--------I 418 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGR-SGALLTRASLDREKVARYTVLVKATDQASPVSD 128 LNP++ ++ R DG L+ + +LDRE+ A + +++ A D P Sbjct: 419 LNPDE--------HFHLEMQMRGDGSVYPELVLKKALDREQQATHRLVLIAEDGGDPPR- 469 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 S + V ++D NDN P+F + Y SV E + ++ ++ ATD D G N +R Sbjct: 470 --SGDVPVIVTVLDTNDNAPEFEQSVYRASVLE--NSPSGTLVVRVHATDLDEGPNGEVR 525 Query: 189 YAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 Y+ + Q F I +G+V++ L ++ ++I A+D G+ + S+T +LL+ Sbjct: 526 YSFSNATAADLQQMFLIHPHTGEVTVSGDLAVQR-PLLEMLIEARDKGAFALSSTAKLLV 584 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNV 305 I DVN++ P + + E+ G I + D D G N ++T + D Sbjct: 585 EITDVNNHGPEITIASLSNPIPEDAVPGTVIALLSIVDKDPGENGKVTCQIPD------- 637 Query: 306 DLPITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 +LP + P Y TSG LDRE + Y + +TATD G PP + T Sbjct: 638 NLPFQLKPSLENYYSLITSGLLDRELISGYNITITATDLGSPPITTQQTLWVQISDVNDN 697 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGR-----FSIT 415 F ++V + E+ P G + ++A+D D E+ ++ Y + G S++ Sbjct: 698 PPVFAADTFDVFVEENNPLGAFLYQVSASDLDIGENGQISYILRNSTVAGSALTSFLSVS 757 Query: 416 SQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447 NG I + DF+Q R + V A D+G Sbjct: 758 LVNGS--IYAKRAFDFEQLRSFHFQVEAKDNG 787 Score = 139 bits (336), Expect = 1e-30 Identities = 108/344 (31%), Positives = 157/344 (45%), Gaps = 27/344 (7%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND++P FE Y ASV E + SGT V+ + ATD D G N EV Y+ TA L Sbjct: 477 VTVLDTNDNAPEFEQSVYRASVLENSPSGTLVVRVHATDLDEGPNGEVRYSFSNATAADL 536 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 Q +F I +G + L ++ +L++A D+ + L Sbjct: 537 ----------------QQMFLIHPHTGEVTVSGDLAVQR-PLLEMLIEARDKG---AFAL 576 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SSTA + V I D N++ P+ + + + + ED VIA + D D G N + Sbjct: 577 SSTAKLLVEITDVNNHGPEITIASLSNPIPED--AVPGTVIALLSIVDKDPGENGKVT-C 633 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 I N Q SL SL+ + LD E + Y + I A D GSP + L + I Sbjct: 634 QIPDNLPFQLK-PSLENYYSLITSGLLDRELISGYNITITATDLGSPPITTQQTLWVQIS 692 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN-VDL 307 DVNDN P F F V EN P+G + +V A D D G N +++Y + + G+ + Sbjct: 693 DVNDNPPVFAADTFDVFVEENNPLGAFLYQVSASDLDIGENGQISYILRNSTVAGSALTS 752 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 +++ +G +Y D E + V A D G P SA T Sbjct: 753 FLSVSLVNGSIYAKRAFDFEQLRSFHFQVEAKDNGSPALSAAMT 796 Score = 127 bits (307), Expect = 4e-27 Identities = 103/326 (31%), Positives = 148/326 (45%), Gaps = 22/326 (6%) Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 S+ E GT V V+ D+GINA +LS+ + Q F IN TG ++ N Sbjct: 281 SIAEGTDRGTFVGNVA---KDLGINAA---ALSARKFRMIIGSSKQYFNINATTGVLSVN 334 Query: 537 KLLDRETMSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 + +DRE + T + + + + +E V+DVNDN P F Y ++ E Sbjct: 335 EPIDREQLCELKSTCLLNYELVLENPLELYRMEFKVLDVNDNSPSFPLSEYRVSVPEFLS 394 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV---IRTNKALDRESVAT 652 G + A D D G NG +Y L+P + + V + KALDRE AT Sbjct: 395 PGARFALPNAQDLDEGTNGVQNYILNPDEHFHLEMQMRGDGSVYPELVLKKALDREQQAT 454 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 H L +A DGG PP+S V V + + D ND+ P FE + ENSP GT + + A Sbjct: 455 HRLVLIAEDGGDPPRSGDVPVIVTVLDTNDNAPEFEQSVYRASVLENSPSGTLVVRVHAT 514 Query: 713 DPDEGPNAVVHYSIK---GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 D DEGPN V YS D F + G E+ DL + P E++I A Sbjct: 515 DLDEGPNGEVRYSFSNATAADLQQMFLIHPHTG----EVTVSGDLAVQRP--LLEMLIEA 568 Query: 770 ASP---PLWNDVRVEILVTDVNDNAP 792 L + ++ + +TDVN++ P Sbjct: 569 RDKGAFALSSTAKLLVEITDVNNHGP 594 Score = 126 bits (304), Expect = 9e-27 Identities = 112/389 (28%), Positives = 176/389 (45%), Gaps = 18/389 (4%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 ++ + D N+ +P F + Y SV E G + +A D D G N Y L+ + Sbjct: 366 MEFKVLDVNDNSPSFPLSEYRVSVPEFLSPGARFALPNAQDLDEGTNGVQNYILNPDEHF 425 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 + P+ + K LDRE + + L + A DGG P S V ++V+D Sbjct: 426 HLEMQMRGDGSVYPE---LVLKKALDREQQATHRLVLIAEDGGDPPRSGDVPVIVTVLDT 482 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE--GSFVI 632 NDN P F+Q +Y A+++E++ GT V +V ATD D G NG + Y + F+I Sbjct: 483 NDNAPEFEQSVYRASVLENSPSGTLVVRVHATDLDEGPNGEVRYSFSNATAADLQQMFLI 542 Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692 P +G + + L + ++ A D G SST + ++I D+N+ P L Sbjct: 543 HPHTGEVTVSGDLAVQRPLL-EMLIEARDKGAFALSSTAKLLVEITDVNNHGPEITIASL 601 Query: 693 TFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752 + I E++ GT I + D D G N V I D+ F L+ + L+T Sbjct: 602 SNPIPEDAVPGTVIALLSIVDKDPGENGKVTCQIP---DNLPFQLKPSL-ENYYSLITSG 657 Query: 753 DLDYESPRKKYELVIRAA---SPPLWNDVRVEILVTDVNDNAPVM-KDFQIIFNNYKDCF 808 LD E Y + I A SPP+ + + ++DVNDN PV D +F ++ Sbjct: 658 LLDRELI-SGYNITITATDLGSPPITTQQTLWVQISDVNDNPPVFAADTFDVF--VEENN 714 Query: 809 PVGPF-GRVPAYDADVTDKLQYRILSGNN 836 P+G F +V A D D+ + Q + N+ Sbjct: 715 PLGAFLYQVSASDLDIGENGQISYILRNS 743 >UniRef50_Q4SM61 Cluster: Chromosome 13 SCAF14555, whole genome shotgun sequence; n=5; Clupeocephala|Rep: Chromosome 13 SCAF14555, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1382 Score = 188 bits (458), Expect = 2e-45 Identities = 224/879 (25%), Positives = 363/879 (41%), Gaps = 97/879 (11%) Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLI 423 F YE + E GT V+ ++A D D + ++ Y + ++ G+I Sbjct: 9 FTSSIYEASVTEGAQIGTSVLQVSAHDKDLGLNGQITYTLLSDSSGDHSLFRIDPELGII 68 Query: 424 TVAQPLDFKQERRYVLTVSATDSG-----GR-----SDTAMVQINITDANNYAPVFENAP 473 D + Y+L V + D G+ SDTA V++ I+D N+ PVF Sbjct: 69 YTEAVFDREARSSYLLEVQSEDGQESARPGKNKQPNSDTAYVRVFISDVNDNKPVFAQRL 128 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAI 533 Y V EDA +G V+ VSATD D G NA++ Y ++S + F I P+ G I Sbjct: 129 YEVGVDEDADVGLAVVTVSATDEDEGANAKLRYQITS-------GNKGGVFDIEPEVGTI 181 Query: 534 TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593 + LD E Y L V A DG D + ++VV+ ND PVF Y ++ E+ Sbjct: 182 FVAQPLDYEQQKRYKLLVLASDG---RWEDYAAIVVTVVNKNDEAPVFSMNEYYGSVTEE 238 Query: 594 ALVGTSVSQVGATDA-----DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648 L G+ V + D + + + L P+D G+ +I + T+ L+ E Sbjct: 239 -LDGSPVFVLQIDDENDNAPEFASSSHLLPPL-PEDVPVGTSIIQVVA--TDTDSGLNGE 294 Query: 649 SVAT----HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 + + D GTP +++V VH+ + D ND+ P E+ + ENSP Sbjct: 295 ILYSILPQSDPHGHFATAGTPALTASVTVHLLLLDTNDNGPELET-AYAPVLWENSPAPQ 353 Query: 705 TI----GEIRAH--DPDEGPNAVVHYSIKGGDDSNSFSLETR-QGSDKAELVTMVDLDYE 757 + H D D N +Y S F L+ GS + M D + + Sbjct: 354 VVWLNQSSTLLHVVDRDSPENGPPYYLSLPSLYSVDFHLQDHGNGSAMLTALRMFDRERQ 413 Query: 758 SPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVP 817 S +++ + PP+ + I + D NDNA + + ++ K G+V Sbjct: 414 SEFHLPVIMVDSGDPPMTATNTLTITIGDQNDNAHQAGEKDVYVHSRKGRVGNAALGKVY 473 Query: 818 AYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLAT-MEVSVTDGV-NE 875 A D D D Y L + A LN+++G +T+ N P + + V V+DGV + Sbjct: 474 APDPDDWDNKTYT-LETSAAKYFSLNQSSGELTI----RQNAPAGSYWLRVGVSDGVWPD 528 Query: 876 IKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPL------LGFFIDGLAAIIPCPKE 929 + + +++ VR + E+ +L+S ++RL +TA F+ L F D L+ + Sbjct: 529 VISGIRVHVRDLEEKAVLSSASLRLTGLTARDFIDSRIEGKSRLETFWDFLSETLSVRTG 588 Query: 930 NIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARL 989 +I IFSV D T ++V F AE G + P L + H+ L L Sbjct: 589 SINIFSVADREQKT---VDVHFYVL---AENG-------YLHPEKLHAVLAAHKRKLQSL 635 Query: 990 ATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEG 1049 V V + + CVH C C T L N+ ++S ++ + C C Sbjct: 636 LRVNVSQVEVDECVHADCRASGGCFTQLSVSNSPSLLDSGALSLVSVKVTPVAVCGC--- 692 Query: 1050 FTGVNCETILTKASCEVDGDGSICRSGSQCVARREGGILCQGCSIDAAYTTAVCELRARS 1109 +T C G+ C +G C+ + G C + C+ S Sbjct: 693 -----AAREMTYRIC-ASYPGNPCLNGGTCMDTKNG----YRCHCPPQFDGPDCQQTRLS 742 Query: 1110 FPVSSFLTFPGLKRRHRIHLKLKFATQTTSGLLLYNGRY-----NERHDFLALELVSSEA 1164 F + + P ++ HL L+F T GLLLY G + D++A+EL+ Sbjct: 743 FLGNGYAWLPPIRPCFDSHLSLEFMTDEDDGLLLYAGPLATLLPGDTEDYMAIELI---- 798 Query: 1165 GRGGGPGLRFSFSLGGGKSEITVEGNVG--DGSWHTVEI 1201 GG P L+ + G G + + N+G +G WH +++ Sbjct: 799 --GGTPSLKMNH--GSGTLVLQLNHNIGVANGRWHRLDV 833 Score = 182 bits (442), Expect = 2e-43 Identities = 151/496 (30%), Positives = 231/496 (46%), Gaps = 39/496 (7%) Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 DVNDN P F +S+++ SV+E IG S+++V A+D D G+N ++TYT+ D +G+ L Sbjct: 1 DVNDNVPFFTSSIYEASVTEGAQIGTSVLQVSAHDKDLGLNGQITYTLLS-DSSGDHSL- 58 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGD--------PPRSATATXXXXXXXXX 360 IDP G +YT DRE ++ Y L V + DG + P S TA Sbjct: 59 FRIDPELGIIYTEAVFDREARSSYLLEVQSEDGQESARPGKNKQPNSDTAYVRVFISDVN 118 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQN 418 F YEV + ED G VVT++ATD DE + +L Y+IT GN G F I + Sbjct: 119 DNKPVFAQRLYEVGVDEDADVGLAVVTVSATDEDEGANAKLRYQITSGNKGGVFDIEPE- 177 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASV 478 G I VAQPLD++Q++RY L V A+D G D A + + + + N+ APVF Y SV Sbjct: 178 -VGTIFVAQPLDYEQQKRYKLLVLASD-GRWEDYAAIVVTVVNKNDEAPVFSMNEYYGSV 235 Query: 479 FEDAPIGTTVLVVSATDSDVGIN--AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 E+ G+ V V+ D + A ++ L + V Q V + Sbjct: 236 TEELD-GSPVFVLQIDDENDNAPEFASSSHLLPPLPEDVPVGTSIIQVVATDTDSGLNGE 294 Query: 537 ---KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED 593 +L + G+ T G P+L+ + V + ++D NDN P + Y + E+ Sbjct: 295 ILYSILPQSDPHGHFAT-----AGTPALTASVTVHLLLLDTNDNGPEL-ETAYAPVLWEN 348 Query: 594 A------LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG--VIRTNKAL 645 + + S + + D D NG +Y P + D +G ++ + Sbjct: 349 SPAPQVVWLNQSSTLLHVVDRDSPENGPPYYLSLPSLYSVDFHLQDHGNGSAMLTALRMF 408 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP-PVFESDCLTFYISENSPIG- 703 DRE + L + +D G PP ++T + I I D ND+ E D + S +G Sbjct: 409 DRERQSEFHLPVIMVDSGDPPMTATNTLTITIGDQNDNAHQAGEKD--VYVHSRKGRVGN 466 Query: 704 TTIGEIRAHDPDEGPN 719 +G++ A DPD+ N Sbjct: 467 AALGKVYAPDPDDWDN 482 Score = 137 bits (332), Expect = 4e-30 Identities = 91/261 (34%), Positives = 135/261 (51%), Gaps = 27/261 (10%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 D ND+ P F YEASV EGA GT+VL + A D+D+G N ++ YT+ +D+ Sbjct: 1 DVNDNVPFFTSSIYEASVTEGAQIGTSVLQVSAHDKDLGLNGQITYTL---LSDSSGD-- 55 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD---QASPVSDRL- 130 +FRID G + T A DRE + Y + V++ D A P ++ Sbjct: 56 ------------HSLFRIDPELGIIYTEAVFDREARSSYLLEVQSEDGQESARPGKNKQP 103 Query: 131 -SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S TA + V I D NDN P F+++ Y V VDED V + + ATD D GAN+ +RY Sbjct: 104 NSDTAYVRVFISDVNDNKPVFAQRLYEVGVDEDADV--GLAVVTVSATDEDEGANAKLRY 161 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 I GN F I+ G + + + LDYEQ + Y+L++ A DG + +++ + + Sbjct: 162 QITSGNKGGVFDIEPEVGTIFVAQPLDYEQQKRYKLLVLASDG---RWEDYAAIVVTVVN 218 Query: 250 VNDNAPRFYTSLFQESVSENV 270 ND AP F + + SV+E + Sbjct: 219 KNDEAPVFSMNEYYGSVTEEL 239 Score = 136 bits (330), Expect = 6e-30 Identities = 83/231 (35%), Positives = 119/231 (51%), Gaps = 16/231 (6%) Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPKDREEGSFV 631 DVNDN P F +Y A++ E A +GTSV QV A D D+GLNG+I Y L + F Sbjct: 1 DVNDNVPFFTSSIYEASVTEGAQIGTSVLQVSAHDKDLGLNGQITYTLLSDSSGDHSLFR 60 Query: 632 IDPASGVIRTNKALDRESVATHDLKAVAIDG--------GTPPQSSTVIVHIKIEDINDS 683 IDP G+I T DRE+ +++ L+ + DG P S T V + I D+ND+ Sbjct: 61 IDPELGIIYTEAVFDREARSSYLLEVQSEDGQESARPGKNKQPNSDTAYVRVFISDVNDN 120 Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 PVF + E++ +G + + A D DEG NA + Y I G+ F +E G+ Sbjct: 121 KPVFAQRLYEVGVDEDADVGLAVVTVSATDEDEGANAKLRYQITSGNKGGVFDIEPEVGT 180 Query: 744 DKAELVTMVDLDYESPRKKYELVIRAASPPLWND-VRVEILVTDVNDNAPV 793 + LDYE +K+Y+L++ AS W D + + V + ND APV Sbjct: 181 ----IFVAQPLDYEQ-QKRYKLLV-LASDGRWEDYAAIVVTVVNKNDEAPV 225 Score = 126 bits (303), Expect = 1e-26 Identities = 144/562 (25%), Positives = 236/562 (41%), Gaps = 51/562 (9%) Query: 142 DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNT--QMQ 199 D NDN P F+ Y SV E + + + ++ A D D+G N I Y ++ ++ Sbjct: 1 DVNDNVPFFTSSIYEASVTEGAQIGTS--VLQVSAHDKDLGLNGQITYTLLSDSSGDHSL 58 Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR--------SNTTQLLINIRDVN 251 F ID G + D E SY L ++++DG +R S+T + + I DVN Sbjct: 59 FRIDPELGIIYTEAVFDREARSSYLLEVQSEDGQESARPGKNKQPNSDTAYVRVFISDVN 118 Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITI 311 DN P F L++ V E+ +G ++V V A D DEG NA+L Y +T +GN I Sbjct: 119 DNKPVFAQRLYEVGVDEDADVGLAVVTVSATDEDEGANAKLRYQIT----SGNKGGVFDI 174 Query: 312 DPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQY 371 +P G ++ + LD E Q +Y+LLV A+DG +A F +Y Sbjct: 175 EPEVGTIFVAQPLDYEQQKRYKLLVLASDGRWEDYAAIVV---TVVNKNDEAPVFSMNEY 231 Query: 372 EVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI-TVAQPLD 430 + E E G+PV L D + DN + + + G +I VA D Sbjct: 232 YGSVTE-ELDGSPVFVLQIDD-ENDNAPEF-ASSSHLLPPLPEDVPVGTSIIQVVATDTD 288 Query: 431 FKQERRYVLTV-SATDSGGRSDTA---------MVQINITDANNYAPVFENAPYTASVFE 480 + ++ +D G TA V + + D N+ P E A Y ++E Sbjct: 289 SGLNGEILYSILPQSDPHGHFATAGTPALTASVTVHLLLLDTNDNGPELETA-YAPVLWE 347 Query: 481 DAP------IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT 534 ++P + + ++ D D N Y LS S +V H Q + +T Sbjct: 348 NSPAPQVVWLNQSSTLLHVVDRDSPENGP-PYYLSLP-SLYSVDFHLQDH--GNGSAMLT 403 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 ++ DRE S + L V D G P ++ T + I++ D NDN ++ + + Sbjct: 404 ALRMFDRERQSEFHLPVIMVDSGDPPMTATNTLTITIGDQNDNAHQAGEKDVYVHSRKGR 463 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654 + ++ +V A D D N Y L+ + F ++ +SG + + ++ Sbjct: 464 VGNAALGKVYAPDPDDWDNKT--YTLETSAAK--YFSLNQSSGELTIRQ---NAPAGSYW 516 Query: 655 LKAVAIDGGTPPQSSTVIVHIK 676 L+ DG P S + VH++ Sbjct: 517 LRVGVSDGVWPDVISGIRVHVR 538 Score = 83.4 bits (197), Expect = 8e-14 Identities = 93/352 (26%), Positives = 146/352 (41%), Gaps = 37/352 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ + D ND+ PVF + YE V E A G V+T+ ATD+D G NA++ Y I Sbjct: 111 RVFISDVNDNKPVFAQRLYEVGVDEDADVGLAVVTVSATDEDEGANAKLRYQI------- 163 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 VF I+ G + LD E+ RY +LV A+D R Sbjct: 164 ------------TSGNKGGVFDIEPEVGTIFVAQPLDYEQQKRYKLLVLASD------GR 205 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD-ADVGANSAIR 188 A I V +++ ND P FS Y SV E++ + V+ D A A+S+ Sbjct: 206 WEDYAAIVVTVVNKNDEAPVFSMNEYYGSVTEELDGSPVFVLQIDDENDNAPEFASSSHL 265 Query: 189 YAIIGGNTQMQFSIDSL---SGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 + + + SI + D L + Y + G+P+ + + + + Sbjct: 266 LPPLPEDVPVGTSIIQVVATDTDSGLNGEILYSILPQSDPHGHFATAGTPALTASVTVHL 325 Query: 246 NIRDVNDNAPRFYTS----LFQESVSENVP-IGYSIVRVQAYDADEGVNAELTYTMTDKD 300 + D NDN P T+ L++ S + V + S + D D N Y Sbjct: 326 LLLDTNDNGPELETAYAPVLWENSPAPQVVWLNQSSTLLHVVDRDSPENGPPYYLSLPSL 385 Query: 301 YTGNVDLPITIDPRSGWVYTSGQL-DRETQAKYQLLVTATDGGDPPRSATAT 351 Y +VD + + T+ ++ DRE Q+++ L V D GDPP +AT T Sbjct: 386 Y--SVDFHLQDHGNGSAMLTALRMFDRERQSEFHLPVIMVDSGDPPMTATNT 435 Score = 65.7 bits (153), Expect = 2e-08 Identities = 68/253 (26%), Positives = 110/253 (43%), Gaps = 16/253 (6%) Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE 738 D+ND+ P F S ++E + IGT++ ++ AHD D G N + Y++ D S SL Sbjct: 1 DVNDNVPFFTSSIYEASVTEGAQIGTSVLQVSAHDKDLGLNGQITYTLLS-DSSGDHSL- 58 Query: 739 TRQGSDKAELVTMVDLDYESPRKKYELVIRA------ASP-----PLWNDVRVEILVTDV 787 R + + T D E+ R Y L +++ A P P + V + ++DV Sbjct: 59 FRIDPELGIIYTEAVFDREA-RSSYLLEVQSEDGQESARPGKNKQPNSDTAYVRVFISDV 117 Query: 788 NDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNET 845 NDN PV +D V A D D KL+Y+I SGN + + Sbjct: 118 NDNKPVFAQRLYEVGVDEDADVGLAVVTVSATDEDEGANAKLRYQITSGNKGGVFDIEPE 177 Query: 846 TGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTA 905 G++ ++ L+ K + V +DG E A + ++V +E + S+ +T Sbjct: 178 VGTIFVAQPLDYEQQKRYKLLVLASDGRWEDYAAIVVTVVNKNDEAPVFSMNEYYGSVTE 237 Query: 906 EQFLSPLLGFFID 918 E SP+ ID Sbjct: 238 ELDGSPVFVLQID 250 Score = 64.9 bits (151), Expect = 3e-08 Identities = 63/214 (29%), Positives = 91/214 (42%), Gaps = 29/214 (13%) Query: 1387 QRDAFVMSIQLKSGLLHYSYN-GETMY---LPMATLSDGAWHRIEIKWLGTDISVTVDYG 1442 Q+ + V+S Q+ GLL YN G+ Y LP LSDG WH +E+ G + ++ +D G Sbjct: 901 QQSSPVLS-QVIQGLLAVFYNLGDGDYNLTLPHQHLSDGEWHELELDRYGREFTLRLDGG 959 Query: 1443 LRTVLMPMLANKIQGQYIGKILIGGLDTTAG--LLASDVGFFEGCIQDVRIGTAQSLLN- 1499 + A++ QGQ +I++ G + F GC++D+R L+ Sbjct: 960 --GGRREVTASRGQGQ---EIVVDPTTVMLGNSFPSGHNHSFLGCMRDLRFNGHSIPLDP 1014 Query: 1500 -------RPTVRENVRDGCQSRADCMLSICPPYSKCVTSWDSSTCTCEAGRV------GP 1546 + + V GC S A C C P CV W C C G + G Sbjct: 1015 EQTSDRLQVVAVQGVSPGCSSEA-CRQHQCSPPLVCVDLWRHHECRCPPGHITRETTQGK 1073 Query: 1547 QCV-SACELGPCGAARCVPDQTPKGYSCACEPGY 1579 C+ + C PC CV +P YSC C GY Sbjct: 1074 VCMYTLCASRPCRHGTCVA-HSPSRYSCHCSEGY 1106 Score = 52.0 bits (119), Expect = 2e-04 Identities = 64/254 (25%), Positives = 103/254 (40%), Gaps = 30/254 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + V++ ND +PVF M +Y SV E G+ V L+ D++ NA E+ L Sbjct: 214 VTVVNKNDEAPVFSMNEYYGSVTEELD-GSPVFVLQIDDEN--DNAP-EFASSSHLLPPL 269 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQ---ASPVS 127 PED D G +G +L Y++L ++ A+ + Sbjct: 270 -PEDVPVGTSIIQVVATDTD--SGLNGEIL------------YSILPQSDPHGHFATAGT 314 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTD----NPVIAKIKATDADVGA 183 L+++ T+H+ ++D NDN P+ E Y + E+ N + D D Sbjct: 315 PALTASVTVHLLLLDTNDNGPEL-ETAYAPVLWENSPAPQVVWLNQSSTLLHVVDRDSPE 373 Query: 184 NSAIRYAIIGGNTQMQFSI-DSLSGDVSL--VKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240 N Y + + F + D +G L ++ D E+ + L + D G P + T Sbjct: 374 NGPPYYLSLPSLYSVDFHLQDHGNGSAMLTALRMFDRERQSEFHLPVIMVDSGDPPMTAT 433 Query: 241 TQLLINIRDVNDNA 254 L I I D NDNA Sbjct: 434 NTLTITIGDQNDNA 447 Score = 38.3 bits (85), Expect = 3.0 Identities = 20/66 (30%), Positives = 26/66 (39%), Gaps = 4/66 (6%) Query: 1287 DFYIDHKFIDLNSYVADNGTLAGCPEKRSRCSSA----PCYNGAECSDLWDTYICDCKEG 1342 D + K DL S + T+ GC C+ PC C W +Y C C+ G Sbjct: 832 DVRSNSKLYDLGSPAEASNTVPGCTLIDGHCTDGEPRPPCGLRGHCHSHWGSYSCLCQPG 891 Query: 1343 HTGKDC 1348 TG C Sbjct: 892 FTGPQC 897 >UniRef50_UPI000069E6F7 Cluster: UPI000069E6F7 related cluster; n=1; Xenopus tropicalis|Rep: UPI000069E6F7 UniRef100 entry - Xenopus tropicalis Length = 602 Score = 188 bits (457), Expect = 3e-45 Identities = 166/565 (29%), Positives = 259/565 (45%), Gaps = 55/565 (9%) Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 +V E +P G + ++A EG E + ++++D V +D +G V T L Sbjct: 9 AVDEGLPPGTLVGDIRA-GLPEGSPGE-GFFLSEEDGESLVLRDFQVDSETGIVSTLQVL 66 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 DRE + Y V AT G+ F +++++E PPGT Sbjct: 67 DRERREHYSF-VAATLQGE-----VVQVDILVRDVNDHSPTFPVHSLQLQVSELTPPGTS 120 Query: 385 VVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGR----------GLITVAQPLDF- 431 A D D E Y + G+ F I +G+ G + PLD Sbjct: 121 FRLPAAWDPDIGEHGLKGYALLRGSQEAPFIIRYGHGKTHNKRMVEGVGADSTLHPLDLV 180 Query: 432 -------KQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 ++ Y L V A D G R+ +V I + DAN+ PVF+ Y V+E+A Sbjct: 181 LIQWLDREELDNYQLEVEAFDGGNPRRTGRLIVDIVVMDANDNPPVFDQLDYKGWVWENA 240 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 PIGT+V V ATD D+G N ++ YSL + F ++ ++G I+ ++ LDRE Sbjct: 241 PIGTSVCTVHATDPDLGSNGEVRYSLR---------FGEGYFTVDEESGEISVSRPLDRE 291 Query: 543 TMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN----IMEDALVGT 598 +S + L V ARDGG + + + V+DVNDN P L T + + E A G Sbjct: 292 QISIHQLVVQARDGGDQPEVTSILLTVKVLDVNDNSPGIHITLITESGRPEVSEGARTGE 351 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDR-----EEGSFVIDPASGVIR---TNKALDRESV 650 ++++ +D D+ + E D + R EGSF + PA + N LDRE Sbjct: 352 YLARIFVSDPDLESEDEVWVEGDTERRLILEGGEGSFSLQPAGPQLYFLCVNAPLDRELK 411 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF-ESDCLTFYISENSPIGTTIGEI 709 ++L+ +A D G+PP S + + + D+ND PP+F + + ISE + IGT + + Sbjct: 412 DMYELQILAWDTGSPPLQSHKTLLLSVTDLNDQPPMFLQPEGYQATISEATSIGTAVLML 471 Query: 710 RAHDPDE-GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768 +A D DE GPN+ V YS++ +S+SF LE G+ + ++D + + Sbjct: 472 KAQDLDEDGPNSRVTYSLQESQNSSSFILEP--GTGVLSIAQLLDHESAPVLNLVAVATD 529 Query: 769 AASPPLWNDVRVEILVTDVNDNAPV 793 SPPL + + I V D NDN P+ Sbjct: 530 HGSPPLSSSCTITITVEDTNDNDPI 554 Score = 181 bits (441), Expect = 2e-43 Identities = 158/542 (29%), Positives = 241/542 (44%), Gaps = 45/542 (8%) Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259 F +DS +G VS ++ LD E+ Y V G Q+ I +RDVND++P F Sbjct: 51 FQVDSETGIVSTLQVLDRERREHYSFVAATLQG------EVVQVDILVRDVNDHSPTFPV 104 Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT------------------DKDY 301 Q VSE P G S A+D D G + Y + +K Sbjct: 105 HSLQLQVSELTPPGTSFRLPAAWDPDIGEHGLKGYALLRGSQEAPFIIRYGHGKTHNKRM 164 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXX 361 V T+ P + LDRE YQL V A DGG+P R+ Sbjct: 165 VEGVGADSTLHPLD--LVLIQWLDREELDNYQLEVEAFDGGNPRRTGRLIVDIVVMDAND 222 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNG 419 F Y+ + E+ P GT V T+ ATD D + + Y + G G F++ ++G Sbjct: 223 NPPVFDQLDYKGWVWENAPIGTSVCTVHATDPDLGSNGEVRYSLRFGE--GYFTVDEESG 280 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSGGRSDTA--MVQINITDANNYAPVFENAPYTAS 477 I+V++PLD +Q + L V A D G + + ++ + + D N+ +P T S Sbjct: 281 E--ISVSRPLDREQISIHQLVVQARDGGDQPEVTSILLTVKVLDVNDNSPGIHITLITES 338 Query: 478 ----VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP---QT 530 V E A G + + +D D+ ++ +E + + F + P Q Sbjct: 339 GRPEVSEGARTGEYLARIFVSDPDLESEDEVWVEGDTE-RRLILEGGEGSFSLQPAGPQL 397 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ-QLYTAN 589 + N LDRE Y L + A D G P L + +SV D+ND P+F Q + Y A Sbjct: 398 YFLCVNAPLDRELKDMYELQILAWDTGSPPLQSHKTLLLSVTDLNDQPPMFLQPEGYQAT 457 Query: 590 IMEDALVGTSVSQVGATDADV-GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648 I E +GT+V + A D D G N R+ Y L + + SF+++P +GV+ + LD E Sbjct: 458 ISEATSIGTAVLMLKAQDLDEDGPNSRVTYSLQ-ESQNSSSFILEPGTGVLSIAQLLDHE 516 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 S +L AVA D G+PP SS+ + I +ED ND+ P+F + E++ +G + Sbjct: 517 SAPVLNLVAVATDHGSPPLSSSCTITITVEDTNDNDPIFLQQFYNVSLQEHTVLGHCFLQ 576 Query: 709 IR 710 +R Sbjct: 577 LR 578 Score = 181 bits (441), Expect = 2e-43 Identities = 156/547 (28%), Positives = 248/547 (45%), Gaps = 65/547 (11%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F++D +G + T LDRE+ Y+ V AT Q V + + + D ND+ P Sbjct: 51 FQVDSETGIVSTLQVLDRERREHYS-FVAATLQGEVVQ--------VDILVRDVNDHSPT 101 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKAT-DADVGANSAIRYAIIGGNTQMQFSIDSLSG- 207 F + + V E +T ++ A D D+G + YA++ G+ + F I G Sbjct: 102 FPVHSLQLQVSE---LTPPGTSFRLPAAWDPDIGEHGLKGYALLRGSQEAPFIIRYGHGK 158 Query: 208 -------------------DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 D+ L++ LD E++ +Y+L + A DGG+P R+ + I + Sbjct: 159 THNKRMVEGVGADSTLHPLDLVLIQWLDREELDNYQLEVEAFDGGNPRRTGRLIVDIVVM 218 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT-DKDYTGNVDL 307 D NDN P F ++ V EN PIG S+ V A D D G N E+ Y++ + Y Sbjct: 219 DANDNPPVFDQLDYKGWVWENAPIGTSVCTVHATDPDLGSNGEVRYSLRFGEGY------ 272 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSA----TATXXXXXXXXXXXX 363 T+D SG + S LDRE + +QL+V A DGGD P T Sbjct: 273 -FTVDEESGEISVSRPLDREQISIHQLVVQARDGGDQPEVTSILLTVKVLDVNDNSPGIH 331 Query: 364 XXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTR--------GRFSIT 415 + E++E G + + +D D ++ + G R G FS+ Sbjct: 332 ITLITESGRPEVSEGARTGEYLARIFVSDPDLESEDEVWVEGDTERRLILEGGEGSFSLQ 391 Query: 416 SQNGR-GLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVF-EN 471 + + V PLD + + Y L + A D+G + +++TD N+ P+F + Sbjct: 392 PAGPQLYFLCVNAPLDRELKDMYELQILAWDTGSPPLQSHKTLLLSVTDLNDQPPMFLQP 451 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDV-GINAQITYSLSSEISNEAVAHHDQQFVINPQT 530 Y A++ E IGT VL++ A D D G N+++TYSL + + F++ P T Sbjct: 452 EGYQATISEATSIGTAVLMLKAQDLDEDGPNSRVTYSLQE-------SQNSSSFILEPGT 504 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590 G ++ +LLD E+ L A D G P LS + + I+V D NDN+P+F QQ Y ++ Sbjct: 505 GVLSIAQLLDHESAPVLNLVAVATDHGSPPLSSSCTITITVEDTNDNDPIFLQQFYNVSL 564 Query: 591 MEDALVG 597 E ++G Sbjct: 565 QEHTVLG 571 Score = 164 bits (398), Expect = 4e-38 Identities = 157/552 (28%), Positives = 248/552 (44%), Gaps = 50/552 (9%) Query: 371 YEVELAEDE--PPGTPVVTLTA--TDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 Y + LA DE PPGT V + A + G + + G+++ Sbjct: 4 YNLSLAVDEGLPPGTLVGDIRAGLPEGSPGEGFFLSEEDGESLVLRDFQVDSETGIVSTL 63 Query: 427 QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGT 486 Q LD ++ R + V+AT G + V I + D N+++P F V E P GT Sbjct: 64 QVLD-RERREHYSFVAATLQG---EVVQVDILVRDVNDHSPTFPVHSLQLQVSELTPPGT 119 Query: 487 TVLVVSATDSDVGINAQITYSLSSEISNEA-----VAH---HDQQFVINPQTGA------ 532 + + +A D D+G + Y+L S EA H H+++ V + Sbjct: 120 SFRLPAAWDPDIGEHGLKGYALLRG-SQEAPFIIRYGHGKTHNKRMVEGVGADSTLHPLD 178 Query: 533 ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592 + + LDRE + Y L V A DGG P + V+I V+D NDN PVF Q Y + E Sbjct: 179 LVLIQWLDREELDNYQLEVEAFDGGNPRRTGRLIVDIVVMDANDNPPVFDQLDYKGWVWE 238 Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652 +A +GTSV V ATD D+G NG + Y L EG F +D SG I ++ LDRE ++ Sbjct: 239 NAPIGTSVCTVHATDPDLGSNGEVRYSL---RFGEGYFTVDEESGEISVSRPLDREQISI 295 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF----YISENSPIGTTIGE 708 H L A DGG P+ +++++ +K+ D+ND+ P +T +SE + G + Sbjct: 296 HQLVVQARDGGDQPEVTSILLTVKVLDVNDNSPGIHITLITESGRPEVSEGARTGEYLAR 355 Query: 709 IRAHDPD-EGPNAV-------VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760 I DPD E + V ++GG+ SFSL+ G L LD E + Sbjct: 356 IFVSDPDLESEDEVWVEGDTERRLILEGGE--GSFSLQP-AGPQLYFLCVNAPLDREL-K 411 Query: 761 KKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRV 816 YEL I A SPPL + + + VTD+ND P+ + + +G + Sbjct: 412 DMYELQILAWDTGSPPLQSHKTLLLSVTDLNDQPPMFLQPEGYQATISEATSIGTAVLML 471 Query: 817 PAYDAD---VTDKLQYRILSGNNANLILLNETTGSMTLSPQL-NTNVPKLATMEVSVTDG 872 A D D ++ Y + N++ +L TG ++++ L + + P L + V+ G Sbjct: 472 KAQDLDEDGPNSRVTYSLQESQNSSSFILEPGTGVLSIAQLLDHESAPVLNLVAVATDHG 531 Query: 873 VNEIKAMMQLSV 884 + + +++ Sbjct: 532 SPPLSSSCTITI 543 Score = 127 bits (306), Expect = 5e-27 Identities = 104/383 (27%), Positives = 172/383 (44%), Gaps = 47/383 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V+D ND+ PVF+ Y+ V E A GT+V T+ ATD D+G N EV Y++ Sbjct: 215 IVVMDANDNPPVFDQLDYKGWVWENAPIGTSVCTVHATDPDLGSNGEVRYSLRF------ 268 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F +D SG + LDRE+++ + ++V+A D Sbjct: 269 ---------------GEGYFTVDEESGEISVSRPLDREQISIHQLVVQARDGGDQPE--- 310 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDIS--VTDNPVIAKIKATDADVGANSAIR 188 ++ + V ++D NDN P T S ++S +A+I +D D+ + + Sbjct: 311 VTSILLTVKVLDVNDNSPGIHITLITESGRPEVSEGARTGEYLARIFVSDPDLESEDEV- 369 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKT------------LDYEQVRSYRLVIRAQDGGSPS 236 + G+T+ + ++ G SL LD E Y L I A D GSP Sbjct: 370 --WVEGDTERRLILEGGEGSFSLQPAGPQLYFLCVNAPLDRELKDMYELQILAWDTGSPP 427 Query: 237 RSNTTQLLINIRDVNDNAPRF-YTSLFQESVSENVPIGYSIVRVQAYDADE-GVNAELTY 294 + LL+++ D+ND P F +Q ++SE IG +++ ++A D DE G N+ +TY Sbjct: 428 LQSHKTLLLSVTDLNDQPPMFLQPEGYQATISEATSIGTAVLMLKAQDLDEDGPNSRVTY 487 Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354 ++ + + + ++P +G + + LD E+ L+ ATD G PP S++ T Sbjct: 488 SLQESQNSSS----FILEPGTGVLSIAQLLDHESAPVLNLVAVATDHGSPPLSSSCTITI 543 Query: 355 XXXXXXXXXXXFMPGQYEVELAE 377 F+ Y V L E Sbjct: 544 TVEDTNDNDPIFLQQFYNVSLQE 566 Score = 93.1 bits (221), Expect = 1e-16 Identities = 76/275 (27%), Positives = 123/275 (44%), Gaps = 19/275 (6%) Query: 11 INVLDCNDHSPVFEMQQYEAS----VREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 + VLD ND+SP + S V EGA +G + + +D D+ +E E +E T Sbjct: 318 VKVLDVNDNSPGIHITLITESGRPEVSEGARTGEYLARIFVSDPDL--ESEDEVWVEGDT 375 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 L E Q F L A LDRE Y + + A D SP Sbjct: 376 ERRLILEGGEGSFSLQPAGPQLYF--------LCVNAPLDRELKDMYELQILAWDTGSPP 427 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 L S T+ +++ D ND P F + + Y ++ E S+ ++ K + D D G NS Sbjct: 428 ---LQSHKTLLLSVTDLNDQPPMFLQPEGYQATISEATSIGTAVLMLKAQDLDED-GPNS 483 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 + Y++ F ++ +G +S+ + LD+E LV A D GSP S++ + I Sbjct: 484 RVTYSLQESQNSSSFILEPGTGVLSIAQLLDHESAPVLNLVAVATDHGSPPLSSSCTITI 543 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQ 280 + D NDN P F + S+ E+ +G+ ++++ Sbjct: 544 TVEDTNDNDPIFLQQFYNVSLQEHTVLGHCFLQLR 578 >UniRef50_A7S9Y2 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 459 Score = 187 bits (456), Expect = 3e-45 Identities = 153/489 (31%), Positives = 235/489 (48%), Gaps = 38/489 (7%) Query: 254 APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313 +P F + F +++EN PIG ++++V A D D L+Y+++ G+ I Sbjct: 1 SPVFSGTPFSATLTENDPIGTTVLKVIAIDEDSADT--LSYSLS-----GSNSAHFAIGS 53 Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373 +G + T+ LDRET Y L V+ +DG A + F Y Sbjct: 54 STGVITTAQLLDRETVNSYSLTVSVSDGTATVNQALSVTINDANDAPL----FTNAPYNA 109 Query: 374 ELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ 433 + E+ G+ V T++ATDAD D + Y I G + +FSI S +G L+T+A +DF+ Sbjct: 110 TVNENAGSGS-VYTVSATDADSDV-IAYSIYGHGS-DKFSIHSSSG--LVTLASAVDFET 164 Query: 434 ERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 + +VLTV A D+ G T + +++ + N+ +P F PY+ S+ E GTTV A Sbjct: 165 KSSFVLTVQAADTNGAIATTSLYVDVVNQND-SPAFMGTPYSTSIIESVSFGTTVFRAQA 223 Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553 D D ++YSLS +N A + F I+P +G ++ LD E S Y+LTV Sbjct: 224 VDEDTA--DTLSYSLSG--TNNAHFAIGELFSIHPTSGVVSVTSALDAEVTSLYVLTVRV 279 Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613 DG +T+ + ++V+DVND P F Y A++ E GT V + ATD D Sbjct: 280 SDG--KGGVNTSSLSVTVIDVND-RPAFVGAPYAASVSERLPSGTGVVTLIATDQD---G 333 Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673 + Y + G F I P++G+I+T + LD ESV ++ L A DG + T V Sbjct: 334 DSLTYSI--SGTNHGHFSISPSTGLIQTAQILDYESVNSYTLTASVTDGSV---TVTTSV 388 Query: 674 HIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN 733 I + + ND PP S I+EN + I +I D D + YS+ G S Sbjct: 389 TISVTNTND-PPTLSSSYYNVSINENDAALSVI-DITGSDSD---GDTLTYSLT-GTGSG 442 Query: 734 SFSLETRQG 742 FS+ + G Sbjct: 443 DFSMNSATG 451 Score = 170 bits (413), Expect = 5e-40 Identities = 151/502 (30%), Positives = 228/502 (45%), Gaps = 48/502 (9%) Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 P FS ++ ++ E+ + + K+ A D D + + Y++ G N+ F+I S +G Sbjct: 2 PVFSGTPFSATLTENDPI--GTTVLKVIAIDED--SADTLSYSLSGSNSA-HFAIGSSTG 56 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 ++ + LD E V SY L + DG + + L + I D ND AP F + + +V+ Sbjct: 57 VITTAQLLDRETVNSYSLTVSVSDG---TATVNQALSVTINDAND-APLFTNAPYNATVN 112 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 EN G S+ V A DAD V A Y G+ +I SG V + +D E Sbjct: 113 ENAGSG-SVYTVSATDADSDVIAYSIY--------GHGSDKFSIHSSSGLVTLASAVDFE 163 Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387 T++ + L V A D + T FM Y + E GT V Sbjct: 164 TKSSFVLTVQAADTNG---AIATTSLYVDVVNQNDSPAFMGTPYSTSIIESVSFGTTVFR 220 Query: 388 LTATDADEDNRLHYEITGGNTRGRFSI----TSQNGRGLITVAQPLDFKQERRYVLTVSA 443 A D D + L Y ++G N F+I + G+++V LD + YVLTV Sbjct: 221 AQAVDEDTADTLSYSLSGTN-NAHFAIGELFSIHPTSGVVSVTSALDAEVTSLYVLTVRV 279 Query: 444 TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503 +D G +T+ + + + D N+ P F APY ASV E P GT V+ + ATD D Sbjct: 280 SDGKGGVNTSSLSVTVIDVND-RPAFVGAPYAASVSERLPSGTGVVTLIATDQD---GDS 335 Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD 563 +TYS+S +H F I+P TG I T ++LD E+++ Y LT + DG S++ Sbjct: 336 LTYSISG-------TNHG-HFSISPSTGLIQTAQILDYESVNSYTLTASVTDG---SVTV 384 Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK 623 TT V ISV + ND P Y +I E+ SV + +D+D + Y L Sbjct: 385 TTSVTISVTNTND-PPTLSSSYYNVSINEND-AALSVIDITGSDSD---GDTLTYSL--T 437 Query: 624 DREEGSFVIDPASGVIRTNKAL 645 G F ++ A+G+I AL Sbjct: 438 GTGSGDFSMNSATGLITLATAL 459 Score = 124 bits (300), Expect = 3e-26 Identities = 135/458 (29%), Positives = 208/458 (45%), Gaps = 33/458 (7%) Query: 466 APVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525 +PVF P++A++ E+ PIGTTVL V A D D ++YSLS SN A F Sbjct: 1 SPVFSGTPFSATLTENDPIGTTVLKVIAIDEDSADT--LSYSLSG--SNSA------HFA 50 Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585 I TG ITT +LLDRET++ Y LTV+ DG + + + +++ D ND P+F Sbjct: 51 IGSSTGVITTAQLLDRETVNSYSLTVSVSDG---TATVNQALSVTINDAND-APLFTNAP 106 Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645 Y A + E+A G SV V ATDAD + I Y + ++ F I +SG++ A+ Sbjct: 107 YNATVNENAGSG-SVYTVSATDADSDV---IAYSIYGHGSDK--FSIHSSSGLVTLASAV 160 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 D E+ ++ L A D T +T +++ + + NDS P F + I E+ GTT Sbjct: 161 DFETKSSFVLTVQAAD--TNGAIATTSLYVDVVNQNDS-PAFMGTPYSTSIIESVSFGTT 217 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765 + RA DE + YS+ G ++++ E + +V++ Y L Sbjct: 218 V--FRAQAVDEDTADTLSYSLSGTNNAHFAIGELFSIHPTSGVVSVTSALDAEVTSLYVL 275 Query: 766 VIRAASPPLW-NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVT 824 +R + N + + V DVND P + + P G G V D Sbjct: 276 TVRVSDGKGGVNTSSLSVTVIDVNDR-PAFVGAPYA-ASVSERLPSGT-GVVTLIATDQD 332 Query: 825 -DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLS 883 D L Y I SG N ++ +TG + + L+ T+ SVTDG + + +S Sbjct: 333 GDSLTYSI-SGTNHGHFSISPSTGLIQTAQILDYESVNSYTLTASVTDGSVTVTTSVTIS 391 Query: 884 VRLITEEMLLNS--ITVRLNDMTAEQFLSPLLGFFIDG 919 V + L+S V +N+ A + + G DG Sbjct: 392 VTNTNDPPTLSSSYYNVSINENDAALSVIDITGSDSDG 429 Score = 94.7 bits (225), Expect = 3e-17 Identities = 87/287 (30%), Positives = 135/287 (47%), Gaps = 37/287 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 ++V++ ND SP F Y S+ E S GTTV +A D+D TADTL Sbjct: 188 VDVVNQND-SPAFMGTPYSTSIIESVSFGTTVFRAQAVDED--------------TADTL 232 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + + + ++F I SG + ++LD E + Y + V+ +D V+ Sbjct: 233 SY--SLSGTNNAHFAIGELFSIHPTSGVVSVTSALDAEVTSLYVLTVRVSDGKGGVN--- 287 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 T+++ V +ID ND P F Y SV E + + V+ I ATD D ++ Y+ Sbjct: 288 --TSSLSVTVIDVNDR-PAFVGAPYAASVSERLP-SGTGVVTLI-ATDQD---GDSLTYS 339 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 I G N FSI +G + + LDYE V SY L DG S + TT + I++ + Sbjct: 340 ISGTN-HGHFSISPSTGLIQTAQILDYESVNSYTLTASVTDG---SVTVTTSVTISVTNT 395 Query: 251 NDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297 ND P +S + S++EN S++ + D+D LTY++T Sbjct: 396 ND-PPTLSSSYYNVSINEN-DAALSVIDITGSDSD---GDTLTYSLT 437 >UniRef50_Q96JP9 Cluster: Protocadherin-21; n=30; Euteleostomi|Rep: Protocadherin-21 - Homo sapiens (Human) Length = 858 Score = 187 bits (455), Expect = 4e-45 Identities = 180/605 (29%), Positives = 259/605 (42%), Gaps = 53/605 (8%) Query: 167 DNPVIAKIKATDADVGANSAIRYAI-IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRL 225 D PV + + + I Y I +T+ FS+D G+++LV+ LD E+ Sbjct: 46 DTPVGSHVYTLNGTDPEGDPISYHISFDPSTRSVFSVDPTFGNITLVEELDREREDEIEA 105 Query: 226 VIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD 285 +I DG +++I + D ND APRF + V E++P G I +V A D D Sbjct: 106 IISISDG---LNLVAEKVVILVTDANDEAPRFIQEPYVALVPEDIPAGSIIFKVHAVDRD 162 Query: 286 EGVNAELTYTMTDKDYTGNVDLPITIDPRSG--WVYTSGQLDRETQAKYQLLVTATDGG- 342 G +TY + N+ P +D SG + LD E + + V A DGG Sbjct: 163 TGSGGSVTY------FLQNLHSPFAVDRHSGVLRLQAGATLDYERSRTHYITVVAKDGGG 216 Query: 343 -----DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--E 395 D SAT T F+ Y + ED PG+ V+ + A D D + Sbjct: 217 RLHGADVVFSATTTVTVNVEDVQDMAPVFVGTPYYGYVYEDTLPGSEVLKVVAMDGDRGK 276 Query: 396 DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD-----SGGRS 450 NR+ Y + GN G F I + G I++ Q Q Y L V T+ S Sbjct: 277 PNRILYSLVNGND-GAFEINETS--GAISITQSPAQLQREVYELHVQVTEMSPAGSPAAQ 333 Query: 451 DTAMVQINITDANNYAPVF--ENAP---YTASVFEDAPIGTTV--LVVSATDSDVGINAQ 503 T V I I D NN+ P F E+ P + S+ E P G + L ++ DSD G NA+ Sbjct: 334 ATVPVTIRIVDLNNHPPTFYGESGPQNRFELSMNEHPPQGEILRGLKITVNDSDQGANAK 393 Query: 504 ITYSLSSEISNEAVAHHDQQFVIN-PQTGAITTNK-LLDRETMSGYLLTVTARDGGVP-S 560 L + + Q V+N Q I N +D E + A + P Sbjct: 394 FNLQL---VGPRGIFRVVPQTVLNEAQVTIIVENSAAIDFEKSKVLTFKLLAVEVNTPEK 450 Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620 S T DV I ++D NDN P F Y A I E+A G+SV V A D D G G + Y Sbjct: 451 FSSTADVVIQLLDTNDNVPKFDSLYYVARIPENAPGGSSVVAVTAVDPDTGPWGEVKYST 510 Query: 621 DPKDREEGSFVIDPASGVIRTN--KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678 + F+I P++G+I T +LD E+ A ++ A D + S V I + Sbjct: 511 YGTGAD--LFLIHPSTGLIYTQPWASLDAEATARYNFYVKAED--MEGKYSVAEVFITLL 566 Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSL 737 D+ND PP F + +GT + +I A D D E PN +V YSI + +N F + Sbjct: 567 DVNDHPPQFGKSVQ----KKTMVLGTPV-KIEAIDEDAEEPNNLVDYSITHAEPANVFDI 621 Query: 738 ETRQG 742 + G Sbjct: 622 NSHTG 626 Score = 159 bits (387), Expect = 8e-37 Identities = 150/504 (29%), Positives = 228/504 (45%), Gaps = 40/504 (7%) Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434 L ED P G+ V TL TD + D ++ +TR FS+ G IT+ + LD ++E Sbjct: 43 LPEDTPVGSHVYTLNGTDPEGDPISYHISFDPSTRSVFSVDPTFGN--ITLVEELDRERE 100 Query: 435 RRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494 +S +D G V I +TDAN+ AP F PY A V ED P G+ + V A Sbjct: 101 DEIEAIISISD-GLNLVAEKVVILVTDANDEAPRFIQEPYVALVPEDIPAGSIIFKVHAV 159 Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554 D D G +TY L + S AV H V+ Q GA LD E + +TV A+ Sbjct: 160 DRDTGSGGSVTYFLQNLHSPFAVDRHSG--VLRLQAGA-----TLDYERSRTHYITVVAK 212 Query: 555 DGG------VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 DGG S TT V ++V DV D PVF Y + ED L G+ V +V A D Sbjct: 213 DGGGRLHGADVVFSATTTVTVNVEDVQDMAPVFVGTPYYGYVYEDTLPGSEVLKVVAMDG 272 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA---LDRESVATHDLKAVAIDGGTP 665 D G RI Y L + +G+F I+ SG I ++ L RE H G+P Sbjct: 273 DRGKPNRILYSL--VNGNDGAFEINETSGAISITQSPAQLQREVYELHVQVTEMSPAGSP 330 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDC-----LTFYISENSPIGTTIG--EIRAHDPDEGP 718 +TV V I+I D+N+ PP F + ++E+ P G + +I +D D+G Sbjct: 331 AAQATVPVTIRIVDLNNHPPTFYGESGPQNRFELSMNEHPPQGEILRGLKITVNDSDQGA 390 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD----LDYESPR-KKYELV-IRAASP 772 NA + + G F + + ++A++ +V+ +D+E + ++L+ + +P Sbjct: 391 NAKFNLQLVG--PRGIFRVVPQTVLNEAQVTIIVENSAAIDFEKSKVLTFKLLAVEVNTP 448 Query: 773 PLWNDVR-VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV--TDKLQY 829 ++ V I + D NDN P + ++ V A D D +++Y Sbjct: 449 EKFSSTADVVIQLLDTNDNVPKFDSLYYVARIPENAPGGSSVVAVTAVDPDTGPWGEVKY 508 Query: 830 RILSGNNANLILLNETTGSMTLSP 853 G A+L L++ +TG + P Sbjct: 509 STY-GTGADLFLIHPSTGLIYTQP 531 Score = 157 bits (381), Expect = 4e-36 Identities = 172/679 (25%), Positives = 295/679 (43%), Gaps = 77/679 (11%) Query: 66 TADTLNPE-DAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQAS 124 T + +PE D + VF +D G + LDRE+ ++ +D + Sbjct: 55 TLNGTDPEGDPISYHISFDPSTRSVFSVDPTFGNITLVEELDREREDEIEAIISISDGLN 114 Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184 V+++ + + + D ND P+F ++ Y V EDI +I K+ A D D G+ Sbjct: 115 LVAEK------VVILVTDANDEAPRFIQEPYVALVPEDIPA--GSIIFKVHAVDRDTGSG 166 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSR----- 237 ++ Y + N F++D SG + L TLDYE+ R++ + + A+DGG Sbjct: 167 GSVTYFL--QNLHSPFAVDRHSGVLRLQAGATLDYERSRTHYITVVAKDGGGRLHGADVV 224 Query: 238 -SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 S TT + +N+ DV D AP F + + V E+ G +++V A D D G + Y++ Sbjct: 225 FSATTTVTVNVEDVQDMAPVFVGTPYYGYVYEDTLPGSEVLKVVAMDGDRGKPNRILYSL 284 Query: 297 TDKDYTGNVDLPITIDPRSGWV---YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXX 353 + GN D I+ SG + + QL RE + + + G P AT Sbjct: 285 VN----GN-DGAFEINETSGAISITQSPAQLQREVYELHVQVTEMSPAGSPAAQATVPVT 339 Query: 354 XXXXXXXXXXXXFM-----PGQYEVELAEDEPPGTPV--VTLTATDADEDNRLHYEITGG 406 F ++E+ + E P G + + +T D+D+ + + Sbjct: 340 IRIVDLNNHPPTFYGESGPQNRFELSMNEHPPQGEILRGLKITVNDSDQGANAKFNLQLV 399 Query: 407 NTRGRFSITSQN--GRGLITV----AQPLDFKQERRY---VLTVSATDSGGRSDTAMVQI 457 RG F + Q +T+ + +DF++ + +L V S TA V I Sbjct: 400 GPRGIFRVVPQTVLNEAQVTIIVENSAAIDFEKSKVLTFKLLAVEVNTPEKFSSTADVVI 459 Query: 458 NITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517 + D N+ P F++ Y A + E+AP G++V+ V+A D D G ++ YS ++ Sbjct: 460 QLLDTNDNVPKFDSLYYVARIPENAPGGSSVVAVTAVDPDTGPWGEVKYSTYGTGAD--- 516 Query: 518 AHHDQQFVINPQTGAITTN--KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575 F+I+P TG I T LD E + Y V A D + +V I+++DVN Sbjct: 517 -----LFLIHPSTGLIYTQPWASLDAEATARYNFYVKAED--MEGKYSVAEVFITLLDVN 569 Query: 576 DNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV-GLNGRIHYELDPKDREEGSFVIDP 634 D+ P F + + + ++GT V ++ A D D N + Y + + F I+ Sbjct: 570 DHPPQFGKSVQKKTM----VLGTPV-KIEAIDEDAEEPNNLVDYSITHAE-PANVFDINS 623 Query: 635 ASGVIRTNKALDRESVATHD----------LKAVAIDGGTPPQSSTVIVHIKIEDINDSP 684 +G I ++ R A H+ L+ A D G+P S+T ++ I DI D+ Sbjct: 624 HTGEIWLKNSI-RSLDALHNITPGRDCLWSLEVQAKDRGSPSFSTTALLKI---DITDAE 679 Query: 685 PVFESDCLTFYI-SENSPI 702 + S F I ++++P+ Sbjct: 680 TLSRSPMAAFLIQTKDNPM 698 Score = 126 bits (304), Expect = 9e-27 Identities = 141/584 (24%), Positives = 236/584 (40%), Gaps = 49/584 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V D ND +P F + Y A V E +G+ + + A D+D G V Y ++ Sbjct: 122 ILVTDANDEAPRFIQEPYVALVPEDIPAGSIIFKVHAVDRDTGSGGSVTYFLQ------- 174 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR--ASLDREKVARYTVLVKATDQASPVSD 128 + F +D SG L + A+LD E+ + + V A D + Sbjct: 175 --------------NLHSPFAVDRHSGVLRLQAGATLDYERSRTHYITVVAKDGGGRLHG 220 Query: 129 R---LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 S+T T+ VN+ D D P F Y V ED + K+ A D D G + Sbjct: 221 ADVVFSATTTVTVNVEDVQDMAPVFVGTPYYGYVYED--TLPGSEVLKVVAMDGDRGKPN 278 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD---GGSPSRSNTTQ 242 I Y+++ GN F I+ SG +S+ ++ Q Y L ++ + GSP+ T Sbjct: 279 RILYSLVNGN-DGAFEINETSGAISITQSPAQLQREVYELHVQVTEMSPAGSPAAQATVP 337 Query: 243 LLINIRDVNDNAPRFY-----TSLFQESVSENVPIGYSI--VRVQAYDADEGVNAELTYT 295 + I I D+N++ P FY + F+ S++E+ P G + +++ D+D+G NA+ Sbjct: 338 VTIRIVDLNNHPPTFYGESGPQNRFELSMNEHPPQGEILRGLKITVNDSDQGANAKFNLQ 397 Query: 296 MTDKDYTGNVDLPITIDPRSG---WVYTSGQLDRETQAKYQLLVTATDGGDPPR-SATAT 351 + V +P T+ + V S +D E + A + P + S+TA Sbjct: 398 LVGPRGIFRV-VPQTVLNEAQVTIIVENSAAIDFEKSKVLTFKLLAVEVNTPEKFSSTAD 456 Query: 352 XXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTR 409 F Y + E+ P G+ VV +TA D D + Y T G Sbjct: 457 VVIQLLDTNDNVPKFDSLYYVARIPENAPGGSSVVAVTAVDPDTGPWGEVKYS-TYGTGA 515 Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVF 469 F I G LD + RY V A D G+ A V I + D N++ P F Sbjct: 516 DLFLIHPSTGLIYTQPWASLDAEATARYNFYVKAEDMEGKYSVAEVFITLLDVNDHPPQF 575 Query: 470 ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 + ++ P+ + A + + ++ IT++ + + + + H + + Sbjct: 576 GKSVQKKTMVLGTPVKIEAIDEDAEEPNNLVDYSITHAEPANVFD--INSHTGEIWLKNS 633 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 ++ + + L V A+D G PS S T ++I + D Sbjct: 634 IRSLDALHNITPGRDCLWSLEVQAKDRGSPSFSTTALLKIDITD 677 Score = 111 bits (267), Expect = 3e-22 Identities = 99/331 (29%), Positives = 156/331 (47%), Gaps = 37/331 (11%) Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 S+ ED P+G+ V ++ TD + I+Y +S + S +V F ++P G IT Sbjct: 42 SLPEDTPVGSHVYTLNGTDPE---GDPISYHISFDPSTRSV------FSVDPTFGNITLV 92 Query: 537 KLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 + LDRE ++ D G+ +++ V I V D ND P F Q+ Y A + ED Sbjct: 93 EELDREREDEIEAIISISD-GLNLVAE--KVVILVTDANDEAPRFIQEPYVALVPEDIPA 149 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR--TNKALDRESVATHD 654 G+ + +V A D D G G + Y L F +D SGV+R LD E TH Sbjct: 150 GSIIFKVHAVDRDTGSGGSVTYFL---QNLHSPFAVDRHSGVLRLQAGATLDYERSRTHY 206 Query: 655 LKAVAIDGGTPPQ------SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 + VA DGG S+T V + +ED+ D PVF Y+ E++ G+ + + Sbjct: 207 ITVVAKDGGGRLHGADVVFSATTTVTVNVEDVQDMAPVFVGTPYYGYVYEDTLPGSEVLK 266 Query: 709 IRAHDPDEG-PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 + A D D G PN ++ YS+ G+D +F + G+ +++ + R+ YEL + Sbjct: 267 VVAMDGDRGKPNRIL-YSLVNGND-GAFEINETSGA-----ISITQSPAQLQREVYELHV 319 Query: 768 R------AASPPLWNDVRVEILVTDVNDNAP 792 + A SP V V I + D+N++ P Sbjct: 320 QVTEMSPAGSPAAQATVPVTIRIVDLNNHPP 350 >UniRef50_UPI0000660953 Cluster: Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2).; n=1; Takifugu rubripes|Rep: Protocadherin-12 precursor (Vascular cadherin-2) (Vascular endothelial cadherin-2) (VE-cadherin-2) (VE-cad-2). - Takifugu rubripes Length = 1134 Score = 186 bits (454), Expect = 6e-45 Identities = 143/489 (29%), Positives = 226/489 (46%), Gaps = 29/489 (5%) Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 N ++ + + D ND++P+F + +SE + I +A D D G N TY+++ Sbjct: 88 NCLRVRVEVMDQNDHSPQFPNAEQDVEISEIAGLRMRIPLERAVDPDAGPNGLQTYSLSV 147 Query: 299 KDYTGNVDLPITIDP---RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355 Y L +T+ P + + +LDRE Q L + A D GDPPRS + Sbjct: 148 NRYFA---LDVTVGPEGTKQAELVIIRELDREVQDSVDLSLVAWDKGDPPRSGSTLIHVR 204 Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEI---TGGNTRG 410 F VEL E+ GT +++L ATD D+ + + Y + T + Sbjct: 205 IQDSNDNSPTFEDSAPTVELPENTARGTTIISLKATDPDQGVNGEVVYSLSKHTQPEVQR 264 Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPV 468 ++ Q +++ PLD++ + Y + V A D G + A +++I D N+ AP Sbjct: 265 LIAVDPQTAA--VSLKAPLDYEVQTSYEVVVEARDRGPNAIPAYCKLHIKLLDVNDNAPR 322 Query: 469 ----FENAPYTA-SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523 ++ + + +V E AP T + +V+ D+D G N ++ + ++ H Sbjct: 323 ILADWDRSSFPGPTVLEGAPKDTFLSLVTVLDADSGQNGKVKAQILEGSGPFSLKH---- 378 Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583 + I TN LDRE ++ Y LT+ A+D G P LS + + VVD NDN PVF Sbjct: 379 --MQGGNYKIVTNGTLDREQVTWYNLTLLAQDYGDPPLSSVKHMSVQVVDENDNAPVFST 436 Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDRE--EGSFVIDPASGVIRT 641 +Y A+ E G + +V A D D+ L+GR+ Y + + F I SGVIR Sbjct: 437 NIYKASFEETNRTGYQMLKVEAHDVDLDLSGRVSYFIRNVTGADVDAYFSIHQTSGVIRA 496 Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF-ESDCLTFYISENS 700 LD E +H AID G PP SS+ V I+++D+ND+ PV E S + Sbjct: 497 QHRLDYEESRSHSFIVEAIDQGHPPLSSSATVQIQVQDVNDNYPVIKEPKPRKGVASLSV 556 Query: 701 PIGTTIGEI 709 P+ GEI Sbjct: 557 PVNADKGEI 565 Score = 182 bits (442), Expect = 2e-43 Identities = 149/511 (29%), Positives = 225/511 (44%), Gaps = 29/511 (5%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F + R G L T+ LDRE++ R + L + + + V ++D ND+ PQ Sbjct: 46 FSVGARDGVLATQGRLDREELCRGSDLCEVAFSVLYRKSGAMNCLRVRVEVMDQNDHSPQ 105 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG-- 207 F V + E + I +A D D G N Y++ + F++D G Sbjct: 106 FPNAEQDVEISEIAGLRMR--IPLERAVDPDAGPNGLQTYSL---SVNRYFALDVTVGPE 160 Query: 208 -----DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLF 262 ++ +++ LD E S L + A D G P RS +T + + I+D NDN+P F S Sbjct: 161 GTKQAELVIIRELDREVQDSVDLSLVAWDKGDPPRSGSTLIHVRIQDSNDNSPTFEDSAP 220 Query: 263 QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322 + EN G +I+ ++A D D+GVN E+ Y+++ K V I +DP++ V Sbjct: 221 TVELPENTARGTTIISLKATDPDQGVNGEVVYSLS-KHTQPEVQRLIAVDPQTAAVSLKA 279 Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE-----LAE 377 LD E Q Y+++V A D G A + + E Sbjct: 280 PLDYEVQTSYEVVVEARDRGPNAIPAYCKLHIKLLDVNDNAPRILADWDRSSFPGPTVLE 339 Query: 378 DEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSIT-SQNGRGLITVAQPLDFKQE 434 P T + +T DAD ++ ++ +I G+ G FS+ Q G I LD +Q Sbjct: 340 GAPKDTFLSLVTVLDADSGQNGKVKAQILEGS--GPFSLKHMQGGNYKIVTNGTLDREQV 397 Query: 435 RRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492 Y LT+ A D G S + + + D N+ APVF Y AS E G +L V Sbjct: 398 TWYNLTLLAQDYGDPPLSSVKHMSVQVVDENDNAPVFSTNIYKASFEETNRTGYQMLKVE 457 Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552 A D D+ ++ +++Y I N A D F I+ +G I LD E + V Sbjct: 458 AHDVDLDLSGRVSYF----IRNVTGADVDAYFSIHQTSGVIRAQHRLDYEESRSHSFIVE 513 Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583 A D G P LS + V+I V DVNDN PV K+ Sbjct: 514 AIDQGHPPLSSSATVQIQVQDVNDNYPVIKE 544 Score = 172 bits (419), Expect = 1e-40 Identities = 122/389 (31%), Positives = 191/389 (49%), Gaps = 26/389 (6%) Query: 423 ITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480 + + + LD + + L++ A D G RS + ++ + I D+N+ +P FE++ T + E Sbjct: 167 LVIIRELDREVQDSVDLSLVAWDKGDPPRSGSTLIHVRIQDSNDNSPTFEDSAPTVELPE 226 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 + GTT++ + ATD D G+N ++ YSLS E + ++PQT A++ LD Sbjct: 227 NTARGTTIISLKATDPDQGVNGEVVYSLSKHTQPEV----QRLIAVDPQTAAVSLKAPLD 282 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF-----KQQLYTANIMEDAL 595 E + Y + V ARD G ++ + I ++DVNDN P + ++E A Sbjct: 283 YEVQTSYEVVVEARDRGPNAIPAYCKLHIKLLDVNDNAPRILADWDRSSFPGPTVLEGAP 342 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG---VIRTNKALDRESVAT 652 T +S V DAD G NG++ ++ G F + G I TN LDRE V Sbjct: 343 KDTFLSLVTVLDADSGQNGKVKAQIL---EGSGPFSLKHMQGGNYKIVTNGTLDREQVTW 399 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 ++L +A D G PP SS + +++ D ND+ PVF ++ E + G + ++ AH Sbjct: 400 YNLTLLAQDYGDPPLSSVKHMSVQVVDENDNAPVFSTNIYKASFEETNRTGYQMLKVEAH 459 Query: 713 DPDEGPNAVVHYSIK---GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELV--I 767 D D + V Y I+ G D FS+ G +A+ LDYE R +V I Sbjct: 460 DVDLDLSGRVSYFIRNVTGADVDAYFSIHQTSGVIRAQ----HRLDYEESRSHSFIVEAI 515 Query: 768 RAASPPLWNDVRVEILVTDVNDNAPVMKD 796 PPL + V+I V DVNDN PV+K+ Sbjct: 516 DQGHPPLSSSATVQIQVQDVNDNYPVIKE 544 Score = 154 bits (374), Expect = 3e-35 Identities = 107/348 (30%), Positives = 175/348 (50%), Gaps = 30/348 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + + D ND+SP FE + E + GTT+++LKATD D G N EV Y++ T Sbjct: 203 VRIQDSNDNSPTFEDSAPTVELPENTARGTTIISLKATDPDQGVNGEVVYSLSKHT---- 258 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 PE VQ + +D ++ A+ +A LD E Y V+V+A D+ + + Sbjct: 259 QPE------------VQRLIAVDPQTAAVSLKAPLDYEVQTSYEVVVEARDRGP---NAI 303 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP---VIAKIKATDADVGANSAI 187 + +H+ ++D NDN P+ S + P ++ + DAD G N + Sbjct: 304 PAYCKLHIKLLDVNDNAPRILADWDRSSFPGPTVLEGAPKDTFLSLVTVLDADSGQNGKV 363 Query: 188 RYAIIGGNTQMQFSIDSLSG-DVSLVK--TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 + I+ G+ FS+ + G + +V TLD EQV Y L + AQD G P S+ + Sbjct: 364 KAQILEGSGP--FSLKHMQGGNYKIVTNGTLDREQVTWYNLTLLAQDYGDPPLSSVKHMS 421 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTG- 303 + + D NDNAP F T++++ S E GY +++V+A+D D ++ ++Y + ++ TG Sbjct: 422 VQVVDENDNAPVFSTNIYKASFEETNRTGYQMLKVEAHDVDLDLSGRVSYFI--RNVTGA 479 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 +VD +I SG + +LD E + +V A D G PP S++AT Sbjct: 480 DVDAYFSIHQTSGVIRAQHRLDYEESRSHSFIVEAIDQGHPPLSSSAT 527 Score = 151 bits (366), Expect = 3e-34 Identities = 164/620 (26%), Positives = 249/620 (40%), Gaps = 81/620 (13%) Query: 6 CIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIEL- 64 C+ ++ V+D NDHSP F + + + E A + +A D D G N Y++ + Sbjct: 89 CLRVRVEVMDQNDHSPQFPNAEQDVEISEIAGLRMRIPLERAVDPDAGPNGLQTYSLSVN 148 Query: 65 --VTAD-TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD 121 D T+ PE + L+ LDRE + + A D Sbjct: 149 RYFALDVTVGPEGT-------------------KQAELVIIRELDREVQDSVDLSLVAWD 189 Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181 + P S + IHV I D NDN P F + TV + E + I +KATD D Sbjct: 190 KGDPPR---SGSTLIHVRIQDSNDNSPTFEDSAPTVELPE--NTARGTTIISLKATDPDQ 244 Query: 182 GANSAIRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238 G N + Y++ Q ++D + VSL LDYE SY +V+ A+D G + Sbjct: 245 GVNGEVVYSLSKHTQPEVQRLIAVDPQTAAVSLKAPLDYEVQTSYEVVVEARDRGPNAIP 304 Query: 239 NTTQLLINIRDVNDNAPRFYTSLFQES-----VSENVPIGYSIVRVQAYDADEGVNAELT 293 +L I + DVNDNAPR + S V E P + V DAD G N ++ Sbjct: 305 AYCKLHIKLLDVNDNAPRILADWDRSSFPGPTVLEGAPKDTFLSLVTVLDADSGQNGKVK 364 Query: 294 YTMTDKDYTGNVDLPITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATA 350 + + +G P ++ G Y T+G LDRE Y L + A D GDPP S+ Sbjct: 365 AQILEG--SG----PFSLKHMQGGNYKIVTNGTLDREQVTWYNLTLLAQDYGDPPLSSVK 418 Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--NRLHY---EITG 405 F Y+ E G ++ + A D D D R+ Y +TG Sbjct: 419 HMSVQVVDENDNAPVFSTNIYKASFEETNRTGYQMLKVEAHDVDLDLSGRVSYFIRNVTG 478 Query: 406 GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDAN 463 + FSI + G+I LD+++ R + V A D G S +A VQI + D N Sbjct: 479 ADVDAYFSIHQTS--GVIRAQHRLDYEESRSHSFIVEAIDQGHPPLSSSATVQIQVQDVN 536 Query: 464 -NYAPVFENAPYTASVFEDAPIGT---TVLVVSATDSDVGINAQITYS-------LSSEI 512 NY + E P P+ ++ T D G A L+S I Sbjct: 537 DNYPVIKEPKPRKGVASLSVPVNADKGEIVTELGTHLD-GTAASFPVDPRTRSGFLASTI 595 Query: 513 SNE--------------AVAHHDQQFVINPQTGAITTNKLLDRETM-SGYLLTVTARDGG 557 E A +H++ F ++ TG + N + + + L + D G Sbjct: 596 KAEDADSGPNGALSYRIAKGNHNRLFWLHEATGQLFVNATNATQLIGQNFKLDIAVSDMG 655 Query: 558 VPSLSDTTDVEISVVDVNDN 577 P L+ T +E++ +++ D+ Sbjct: 656 SPRLTTTMTLEVTFINLRDH 675 Score = 135 bits (326), Expect = 2e-29 Identities = 117/425 (27%), Positives = 193/425 (45%), Gaps = 24/425 (5%) Query: 448 GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507 G + V++ + D N+++P F NA + E A + + + A D D G N TYS Sbjct: 85 GAMNCLRVRVEVMDQNDHSPQFPNAEQDVEISEIAGLRMRIPLERAVDPDAGPNGLQTYS 144 Query: 508 LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567 LS N A + + + LDRE L++ A D G P S +T + Sbjct: 145 LS---VNRYFALDVTVGPEGTKQAELVIIRELDREVQDSVDLSLVAWDKGDPPRSGSTLI 201 Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627 + + D NDN P F+ T + E+ GT++ + ATD D G+NG + Y L + E Sbjct: 202 HVRIQDSNDNSPTFEDSAPTVELPENTARGTTIISLKATDPDQGVNGEVVYSLSKHTQPE 261 Query: 628 GS--FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685 +DP + + LD E ++++ A D G + +HIK+ D+ND+ P Sbjct: 262 VQRLIAVDPQTAAVSLKAPLDYEVQTSYEVVVEARDRGPNAIPAYCKLHIKLLDVNDNAP 321 Query: 686 --VFESDCLTF---YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR 740 + + D +F + E +P T + + D D G N V I G S FSL+ Sbjct: 322 RILADWDRSSFPGPTVLEGAPKDTFLSLVTVLDADSGQNGKVKAQILEG--SGPFSLKHM 379 Query: 741 QGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPVMKDF 797 QG + ++VT LD E Y L + A PPL + + + V D NDNAPV Sbjct: 380 QGGN-YKIVTNGTLDREQV-TWYNLTLLAQDYGDPPLSSVKHMSVQVVDENDNAPVFST- 436 Query: 798 QIIFNNYKDCFPVG-PFGRVPAYDA--DVTDKLQYRILSGNNANL---ILLNETTGSMTL 851 I ++++ G +V A+D D++ ++ Y I + A++ +++T+G + Sbjct: 437 NIYKASFEETNRTGYQMLKVEAHDVDLDLSGRVSYFIRNVTGADVDAYFSIHQTSGVIRA 496 Query: 852 SPQLN 856 +L+ Sbjct: 497 QHRLD 501 Score = 105 bits (252), Expect = 2e-20 Identities = 89/287 (31%), Positives = 127/287 (44%), Gaps = 29/287 (10%) Query: 524 FVINPQTGAITTNKLLDRETMSG------YLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577 F + + G + T LDRE + +V R G + V + V+D ND+ Sbjct: 46 FSVGARDGVLATQGRLDREELCRGSDLCEVAFSVLYRKSGA---MNCLRVRVEVMDQNDH 102 Query: 578 EPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG 637 P F I E A + + A D D G NG Y L F +D G Sbjct: 103 SPQFPNAEQDVEISEIAGLRMRIPLERAVDPDAGPNGLQTYSLSVNRY----FALDVTVG 158 Query: 638 VIRTNKA-------LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690 T +A LDRE + DL VA D G PP+S + ++H++I+D ND+ P FE Sbjct: 159 PEGTKQAELVIIRELDREVQDSVDLSLVAWDKGDPPRSGSTLIHVRIQDSNDNSPTFEDS 218 Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750 T + EN+ GTTI ++A DPD+G N V YS+ L A + Sbjct: 219 APTVELPENTARGTTIISLKATDPDQGVNGEVVYSLSKHTQPEVQRL-IAVDPQTAAVSL 277 Query: 751 MVDLDYESPRKKYELVIRAA-----SPPLWNDVRVEILVTDVNDNAP 792 LDYE + YE+V+ A + P + + +++L DVNDNAP Sbjct: 278 KAPLDYE-VQTSYEVVVEARDRGPNAIPAYCKLHIKLL--DVNDNAP 321 >UniRef50_UPI000054713A Cluster: PREDICTED: hypothetical protein; n=1; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 1026 Score = 185 bits (451), Expect = 1e-44 Identities = 141/483 (29%), Positives = 231/483 (47%), Gaps = 29/483 (6%) Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + + D+ND+ P F + L + +SE + I +A D D G N TYT++ + Sbjct: 100 VEVMDLNDHNPVFPSLLQEVEISETASLRMRIPLDRAADPDAGPNGLQTYTLSSNQHFA- 158 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 +D+ + + + +LDRE QA +L + A D G+PP+S + Sbjct: 159 LDVRSFGGAKQAELVVTKELDRELQASLELELIAWDKGNPPKSGSTKIIVTILDSNDNSP 218 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGN---TRGRFSITSQNG 419 F +ELAE+ GT V+ L ATD D+ + + Y ++ + + FSI + G Sbjct: 219 IFEEAPSVIELAENTIRGTIVLNLRATDPDQGANGEVEYSLSKHSPLEVQRLFSIHPKTG 278 Query: 420 RGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFE------N 471 +T+ PLDF+++ Y + + A D G G +QI + D N+ AP + Sbjct: 279 A--LTLQGPLDFEEKNVYEVDIQARDLGPNGIPSHHKLQIKLQDINDNAPRIHITWTPPD 336 Query: 472 APYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG 531 +P A+V E AP T + +V +D+D G N Q+ + ++ Q I+ Sbjct: 337 SP-VATVTEGAPNETFLALVMVSDADYGANGQVQVHI---LTGSGPFRLKQ---IHGDNY 389 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 I TN LDRE Y LT+ A+D G PSLS + + V+D NDN P+F + Y + + Sbjct: 390 MIVTNGTLDREKQMEYNLTLLAQDSGDPSLSCIKHLTVHVLDENDNPPIFTKSHYRSILK 449 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS----FVIDPASGVIRTNKALDR 647 E+ G V A D D+GL+G++ + + + E G+ F + P+SG + ++LD Sbjct: 450 ENNTPGFHFLTVEAHDVDLGLSGQVSFSI-RESNELGTPTAFFSVHPSSGEVTVQQSLDY 508 Query: 648 ESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS-ENSPIGTTI 706 E + A+D G PP +S V ++I+D+ND+ P+ I+ N P+ Sbjct: 509 EESRVYSFIVEAVDQGYPPMTSIAAVLVEIQDVNDNYPIIYEPLPKKGIALLNVPVNVDK 568 Query: 707 GEI 709 GEI Sbjct: 569 GEI 571 Score = 161 bits (391), Expect = 3e-37 Identities = 134/508 (26%), Positives = 228/508 (44%), Gaps = 23/508 (4%) Query: 92 IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151 + R G + T LDRE++ T L + ++ V ++D ND+ P F Sbjct: 54 VASRDGTVSTFGRLDREELCWGTELCELAFNVLYRKGGAMHLLSVRVEVMDLNDHNPVFP 113 Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG---- 207 V + E S+ I +A D D G N Y + N + S G Sbjct: 114 SLLQEVEISETASLRMR--IPLDRAADPDAGPNGLQTYTL-SSNQHFALDVRSFGGAKQA 170 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 ++ + K LD E S L + A D G+P +S +T++++ I D NDN+P F + ++ Sbjct: 171 ELVVTKELDRELQASLELELIAWDKGNPPKSGSTKIIVTILDSNDNSPIFEEAPSVIELA 230 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 EN G ++ ++A D D+G N E+ Y+++ K V +I P++G + G LD E Sbjct: 231 ENTIRGTIVLNLRATDPDQGANGEVEYSLS-KHSPLEVQRLFSIHPKTGALTLQGPLDFE 289 Query: 328 TQAKYQLLVTATD---GGDPP-RSATATXXXXXXXXXXXXXXFMPGQYEV-ELAEDEPPG 382 + Y++ + A D G P + P V + E P Sbjct: 290 EKNVYEVDIQARDLGPNGIPSHHKLQIKLQDINDNAPRIHITWTPPDSPVATVTEGAPNE 349 Query: 383 TPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ-PLDFKQERRYVL 439 T + + +DAD + ++ I G+ G F + +G + V LD +++ Y L Sbjct: 350 TFLALVMVSDADYGANGQVQVHILTGS--GPFRLKQIHGDNYMIVTNGTLDREKQMEYNL 407 Query: 440 TVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497 T+ A DSG S + + + +++ D N+ P+F + Y + + E+ G L V A D D Sbjct: 408 TLLAQDSGDPSLSCIKHLTVHVLDENDNPPIFTKSHYRSILKENNTPGFHFLTVEAHDVD 467 Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG 557 +G++ Q+++S+ SNE + F ++P +G +T + LD E Y V A D G Sbjct: 468 LGLSGQVSFSIRE--SNE-LGTPTAFFSVHPSSGEVTVQQSLDYEESRVYSFIVEAVDQG 524 Query: 558 VPSLSDTTDVEISVVDVNDNEPVFKQQL 585 P ++ V + + DVNDN P+ + L Sbjct: 525 YPPMTSIAAVLVEIQDVNDNYPIIYEPL 552 Score = 161 bits (390), Expect = 3e-37 Identities = 140/507 (27%), Positives = 218/507 (42%), Gaps = 27/507 (5%) Query: 307 LPITIDPRSGWVYTSGQLDRE-----TQ-AKYQLLVTATDGGDPPRSATATXXXXXXXXX 360 LP+T+ R G V T G+LDRE T+ + V GG + Sbjct: 50 LPVTVASRDGTVSTFGRLDREELCWGTELCELAFNVLYRKGGAMHLLSVRVEVMDLNDHN 109 Query: 361 XXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED-NRLHYEITGGNTRGRFSITSQNG 419 + EVE++E + A D D N L N + S G Sbjct: 110 PVFPSLLQ---EVEISETASLRMRIPLDRAADPDAGPNGLQTYTLSSNQHFALDVRSFGG 166 Query: 420 --RGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYT 475 + + V + LD + + L + A D G +S + + + I D+N+ +P+FE AP Sbjct: 167 AKQAELVVTKELDRELQASLELELIAWDKGNPPKSGSTKIIVTILDSNDNSPIFEEAPSV 226 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 + E+ GT VL + ATD D G N ++ YSLS E + F I+P+TGA+T Sbjct: 227 IELAENTIRGTIVLNLRATDPDQGANGEVEYSLSKHSPLEV----QRLFSIHPKTGALTL 282 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFK-----QQLYTANI 590 LD E + Y + + ARD G + ++I + D+NDN P A + Sbjct: 283 QGPLDFEEKNVYEVDIQARDLGPNGIPSHHKLQIKLQDINDNAPRIHITWTPPDSPVATV 342 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650 E A T ++ V +DAD G NG++ + I + +I TN LDRE Sbjct: 343 TEGAPNETFLALVMVSDADYGANGQVQVHILTGSGPFRLKQIHGDNYMIVTNGTLDREKQ 402 Query: 651 ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIR 710 ++L +A D G P S + + + D ND+PP+F + EN+ G + Sbjct: 403 MEYNLTLLAQDSGDPSLSCIKHLTVHVLDENDNPPIFTKSHYRSILKENNTPGFHFLTVE 462 Query: 711 AHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA 770 AHD D G + V +SI+ ++ + + E+ LDYE R Y ++ A Sbjct: 463 AHDVDLGLSGQVSFSIRESNELGTPTAFFSVHPSSGEVTVQQSLDYEESR-VYSFIVEAV 521 Query: 771 S---PPLWNDVRVEILVTDVNDNAPVM 794 PP+ + V + + DVNDN P++ Sbjct: 522 DQGYPPMTSIAAVLVEIQDVNDNYPII 548 Score = 157 bits (382), Expect = 3e-36 Identities = 140/494 (28%), Positives = 214/494 (43%), Gaps = 47/494 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ V+D NDH+PVF E + E AS + +A D D G N YT+ + Sbjct: 99 RVEVMDLNDHNPVFPSLLQEVEISETASLRMRIPLDRAADPDAGPNGLQTYTL------S 152 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 N A DV G + L+ LDRE A + + A D+ +P Sbjct: 153 SNQHFAL-----------DVRSFGGAKQAELVVTKELDRELQASLELELIAWDKGNPPK- 200 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 S + I V I+D NDN P F E + + E + ++ ++ATD D GAN + Sbjct: 201 --SGSTKIIVTILDSNDNSPIFEEAPSVIELAE--NTIRGTIVLNLRATDPDQGANGEVE 256 Query: 189 YAIIGGN---TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 Y++ + Q FSI +G ++L LD+E+ Y + I+A+D G + +L I Sbjct: 257 YSLSKHSPLEVQRLFSIHPKTGALTLQGPLDFEEKNVYEVDIQARDLGPNGIPSHHKLQI 316 Query: 246 NIRDVNDNAPRFYTSLFQ-----ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 ++D+NDNAPR + + +V+E P + V DAD G N ++ + Sbjct: 317 KLQDINDNAPRIHITWTPPDSPVATVTEGAPNETFLALVMVSDADYGANGQVQVHI---- 372 Query: 301 YTGNVDLPI-TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 TG+ + I + + T+G LDRE Q +Y L + A D GDP S Sbjct: 373 LTGSGPFRLKQIHGDNYMIVTNGTLDREKQMEYNLTLLAQDSGDPSLSCIKHLTVHVLDE 432 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGR----FS 413 F Y L E+ PG +T+ A D D ++ + I N G FS Sbjct: 433 NDNPPIFTKSHYRSILKENNTPGFHFLTVEAHDVDLGLSGQVSFSIRESNELGTPTAFFS 492 Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDAN-NYAPVFE 470 + +G +TV Q LD+++ R Y V A D G + A V + I D N NY ++E Sbjct: 493 VHPSSGE--VTVQQSLDYEESRVYSFIVEAVDQGYPPMTSIAAVLVEIQDVNDNYPIIYE 550 Query: 471 NAPYTASVFEDAPI 484 P + P+ Sbjct: 551 PLPKKGIALLNVPV 564 Score = 106 bits (255), Expect = 8e-21 Identities = 89/294 (30%), Positives = 137/294 (46%), Gaps = 25/294 (8%) Query: 515 EAVAH-HDQQFVINPQTGAITTNKLLDRETMSG------YLLTVTARDGGVPSLSDTTDV 567 + V H H + + G ++T LDRE + V R GG L V Sbjct: 42 QVVQHGHALPVTVASRDGTVSTFGRLDREELCWGTELCELAFNVLYRKGGAMHL---LSV 98 Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR-- 625 + V+D+ND+ PVF L I E A + + A D D G NG Y L Sbjct: 99 RVEVMDLNDHNPVFPSLLQEVEISETASLRMRIPLDRAADPDAGPNGLQTYTLSSNQHFA 158 Query: 626 -EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP 684 + SF + ++ T K LDRE A+ +L+ +A D G PP+S + + + I D ND+ Sbjct: 159 LDVRSFGGAKQAELVVT-KELDRELQASLELELIAWDKGNPPKSGSTKIIVTILDSNDNS 217 Query: 685 PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGG---DDSNSFSLETRQ 741 P+FE ++EN+ GT + +RA DPD+G N V YS+ + FS+ + Sbjct: 218 PIFEEAPSVIELAENTIRGTIVLNLRATDPDQGANGEVEYSLSKHSPLEVQRLFSIHPKT 277 Query: 742 GSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792 G+ L LD+E + YE+ I+A + + +++I + D+NDNAP Sbjct: 278 GA----LTLQGPLDFEE-KNVYEVDIQARDLGPNGIPSHHKLQIKLQDINDNAP 326 Score = 70.1 bits (164), Expect = 8e-10 Identities = 57/224 (25%), Positives = 105/224 (46%), Gaps = 13/224 (5%) Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732 V +++ D+ND PVF S ISE + + I RA DPD GPN + Y++ + Sbjct: 98 VRVEVMDLNDHNPVFPSLLQEVEISETASLRMRIPLDRAADPDAGPNGLQTYTLSS---N 154 Query: 733 NSFSLETRQ--GSDKAELVTMVDLDYESPRK-KYELVI-RAASPPLWNDVRVEILVTDVN 788 F+L+ R G+ +AELV +LD E + EL+ +PP ++ + + D N Sbjct: 155 QHFALDVRSFGGAKQAELVVTKELDRELQASLELELIAWDKGNPPKSGSTKIIVTILDSN 214 Query: 789 DNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNN---ANLILLN 843 DN+P+ ++ + ++ + A D D +++Y + + L ++ Sbjct: 215 DNSPIFEEAPSVIELAENTIRGTIVLNLRATDPDQGANGEVEYSLSKHSPLEVQRLFSIH 274 Query: 844 ETTGSMTLSPQLNTNVPKLATMEVSVTD-GVNEIKAMMQLSVRL 886 TG++TL L+ + +++ D G N I + +L ++L Sbjct: 275 PKTGALTLQGPLDFEEKNVYEVDIQARDLGPNGIPSHHKLQIKL 318 Score = 64.1 bits (149), Expect = 5e-08 Identities = 66/266 (24%), Positives = 118/266 (44%), Gaps = 25/266 (9%) Query: 6 CI-HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIEL 64 CI H ++VLD ND+ P+F Y + ++E + G LT++A D D+G + +V ++I Sbjct: 421 CIKHLTVHVLDENDNPPIFTKSHYRSILKENNTPGFHFLTVEAHDVDLGLSGQVSFSIR- 479 Query: 65 VTADTLNPEDAXXXXXXXXXXV---QDVFRIDGRSGALLTRASLDR-----EKVARYTVL 116 ++ L A V Q + + R + + A +D+ +A V Sbjct: 480 -ESNELGTPTAFFSVHPSSGEVTVQQSLDYEESRVYSFIVEA-VDQGYPPMTSIAAVLVE 537 Query: 117 VKATDQASPVS-DRLSSTATIHVNI---IDDNDNYPQFSEKTYTVSVDE--DISVTDNP- 169 ++ + P+ + L +N+ +D + + +K + + + S + P Sbjct: 538 IQDVNDNYPIIYEPLPKKGIALLNVPVNVDKGEIVTELGDKAMEDNFHKHRNYSSLNKPE 597 Query: 170 --VIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV-RSYRLV 226 + I+A+D D G N + + I GGN F +D SG+ + T E + R+++L Sbjct: 598 GFLATTIRASDPDSGLNGRLNFGITGGNPSNIFFLDKTSGEFYVNTTNATELIGRTFKLG 657 Query: 227 IRAQDGGSPSRSNTTQL---LINIRD 249 I D G+P S T L IN RD Sbjct: 658 IEVSDMGTPILSTRTTLEVTFINFRD 683 Score = 41.9 bits (94), Expect = 0.25 Identities = 21/48 (43%), Positives = 26/48 (54%) Query: 695 YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQG 742 Y S N P G IRA DPD G N +++ I GG+ SN F L+ G Sbjct: 590 YSSLNKPEGFLATTIRASDPDSGLNGRLNFGITGGNPSNIFFLDKTSG 637 >UniRef50_Q7YZI2 Cluster: PRCDH1; n=1; Proterospongia sp. ATCC 50818|Rep: PRCDH1 - Proterospongia sp. ATCC 50818 Length = 496 Score = 185 bits (451), Expect = 1e-44 Identities = 155/523 (29%), Positives = 254/523 (48%), Gaps = 44/523 (8%) Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ-FSIDSLS 206 P F++ V++ E S+ D + +++ATD D + IRY ++ G+T F +D++ Sbjct: 8 PVFTQDLVRVTLLETASLGD--YVTRVEATDQDCADEAEIRYRVVSGDTTPPTFDLDTVG 65 Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266 G ++LV+ LD+ + S+ L + A DG S+T +LIN+ + + + P F +S + + Sbjct: 66 GVITLVRELDFAERSSFSLQLSASDG---DLSDTMYVLINVVETSPDFPLFTSSRYTADL 122 Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326 +E+ IG ++ V G+ ++++T GN +D SG + ++ Sbjct: 123 AESASIGTTVATVATNRT--GI---ASFSITG----GNSAGKFAVDANSGAITLMSRVCA 173 Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386 ++ Y L V A P + F QY V ++E G+ ++ Sbjct: 174 ASEDAYSLQVQAQSKTRPDLQSYTLVDVSVVPANTAAPAFSQAQYSVNVSETGSVGSVLL 233 Query: 387 TLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE----RRYVLTVS 442 L ATDAD + + Y ITGGN+ G F+I + G + V QPL+ ++ LTV+ Sbjct: 234 QLQATDADCRDAVTYRITGGNSNGLFAINRETGE--LAVVQPLNADVSSGGAAQHTLTVA 291 Query: 443 ATD---SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499 ATD S R+ TA V + + + N YAPVF A Y+ + + GT +++V ATD+D G Sbjct: 292 ATDDFASSPRTSTATVLVTVLNVNQYAPVFA-ATYSGTFADSVSTGTELVLVGATDAD-G 349 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 N I Y+++S + F I+ TG++T + T S Y L VTA D G P Sbjct: 350 DN--IAYAITS-------GNTGNVFAIDAVTGSLTLAAPVCSRTQSSYTLVVTATDDGQP 400 Query: 560 -SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618 + S T V++S N PVF+Q Y + D+ + +V ATDAD + I Y Sbjct: 401 EARSAGTVVQLSFSASNAASPVFEQASY--SFTADSSLNAYAGRVRATDAD--CDDSITY 456 Query: 619 ELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 L+ + +F I P +GVI L +++ + L AVA D Sbjct: 457 TLN--RNTQFAFTIHPTTGVITVVAPLTQDT--PYVLDAVATD 495 Score = 167 bits (407), Expect = 3e-39 Identities = 154/544 (28%), Positives = 253/544 (46%), Gaps = 63/544 (11%) Query: 20 SPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXX 79 +PVF ++ E AS G V ++ATDQD AE+ Y + V+ DT P Sbjct: 7 APVFTQDLVRVTLLETASLGDYVTRVEATDQDCADEAEIRYRV--VSGDTTPP------- 57 Query: 80 XXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVN 139 F +D G + LD + + +++ + A+D LS T + +N Sbjct: 58 ---------TFDLDTVGGVITLVRELDFAERSSFSLQLSASD------GDLSDTMYVLIN 102 Query: 140 IIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQ 199 +++ + ++P F+ YT + E S+ +A + + + ++I GGN+ + Sbjct: 103 VVETSPDFPLFTSSRYTADLAESASI--GTTVATVATNRTGIAS-----FSITGGNSAGK 155 Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259 F++D+ SG ++L+ + +Y L ++AQ P + T + +++ N AP F Sbjct: 156 FAVDANSGAITLMSRVCAASEDAYSLQVQAQSKTRPDLQSYTLVDVSVVPANTAAPAFSQ 215 Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319 + + +VSE +G ++++QA DAD +TY +T GN + I+ +G + Sbjct: 216 AQYSVNVSETGSVGSVLLQLQATDAD--CRDAVTYRITG----GNSNGLFAINRETGELA 269 Query: 320 TSGQLDRETQ----AKYQLLVTATDG-GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374 L+ + A++ L V ATD PR++TAT F Y Sbjct: 270 VVQPLNADVSSGGAAQHTLTVAATDDFASSPRTSTATVLVTVLNVNQYAPVF-AATYSGT 328 Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434 A+ GT +V + ATDAD DN + Y IT GNT F+I + G +T+A P+ + + Sbjct: 329 FADSVSTGTELVLVGATDADGDN-IAYAITSGNTGNVFAIDAVTGS--LTLAAPVCSRTQ 385 Query: 435 RRYVLTVSATDSG---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491 Y L V+ATD G RS +VQ++ + +N +PVFE A Y S D+ + V Sbjct: 386 SSYTLVVTATDDGQPEARSAGTVVQLSFSASNAASPVFEQASY--SFTADSSLNAYAGRV 443 Query: 492 SATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTV 551 ATD+D + ITY+L+ N A F I+P TG IT L ++T Y+L Sbjct: 444 RATDAD--CDDSITYTLN---RNTQFA-----FTIHPTTGVITVVAPLTQDT--PYVLDA 491 Query: 552 TARD 555 A D Sbjct: 492 VATD 495 Score = 144 bits (350), Expect = 2e-32 Identities = 139/499 (27%), Positives = 227/499 (45%), Gaps = 40/499 (8%) Query: 373 VELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 V L E G V + ATD D ++ + Y + G+T G G+IT+ + LD Sbjct: 17 VTLLETASLGDYVTRVEATDQDCADEAEIRYRVVSGDTTPPTFDLDTVG-GVITLVRELD 75 Query: 431 FKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 F + + L +SA+D G SDT V IN+ + + P+F ++ YTA + E A IGTTV Sbjct: 76 FAERSSFSLQLSASD-GDLSDTMYVLINVVETSPDFPLFTSSRYTADLAESASIGTTVAT 134 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLT 550 V+ + + ++S++ N A +F ++ +GAIT + + Y L Sbjct: 135 VATNRTGIA-----SFSITG--GNSA-----GKFAVDANSGAITLMSRVCAASEDAYSLQ 182 Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610 V A+ P L T V++SVV N P F Q Y+ N+ E VG+ + Q+ ATDAD Sbjct: 183 VQAQSKTRPDLQSYTLVDVSVVPANTAAPAFSQAQYSVNVSETGSVGSVLLQLQATDAD- 241 Query: 611 GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE----SVATHDLKAVAIDG-GTP 665 + Y + G F I+ +G + + L+ + A H L A D + Sbjct: 242 -CRDAVTYRI-TGGNSNGLFAINRETGELAVVQPLNADVSSGGAAQHTLTVAATDDFASS 299 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 P++ST V + + ++N PVF + + +++ GT + + A D D G N + Y+ Sbjct: 300 PRTSTATVLVTVLNVNQYAPVFAA-TYSGTFADSVSTGTELVLVGATDAD-GDN--IAYA 355 Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWN-DVRVE 781 I G+ N F+++ GS +T+ + Y LV+ A P + V+ Sbjct: 356 ITSGNTGNVFAIDAVTGS-----LTLAAPVCSRTQSSYTLVVTATDDGQPEARSAGTVVQ 410 Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLIL 841 + + N +PV + Q ++ D GRV A DAD D + Y L+ N Sbjct: 411 LSFSASNAASPVFE--QASYSFTADSSLNAYAGRVRATDADCDDSITY-TLNRNTQFAFT 467 Query: 842 LNETTGSMTLSPQLNTNVP 860 ++ TTG +T+ L + P Sbjct: 468 IHPTTGVITVVAPLTQDTP 486 Score = 144 bits (348), Expect = 4e-32 Identities = 130/471 (27%), Positives = 206/471 (43%), Gaps = 37/471 (7%) Query: 254 APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP 313 AP F L + ++ E +G + RV+A D D AE+ Y + D T +D Sbjct: 7 APVFTQDLVRVTLLETASLGDYVTRVEATDQDCADEAEIRYRVVSGDTTPPT---FDLDT 63 Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373 G + +LD ++ + L ++A+DG S T F +Y Sbjct: 64 VGGVITLVRELDFAERSSFSLQLSASDG---DLSDTMYVLINVVETSPDFPLFTSSRYTA 120 Query: 374 ELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ 433 +LAE GT V T+ + + ITGGN+ G+F++ + + G IT+ + Sbjct: 121 DLAESASIGTTVATVA---TNRTGIASFSITGGNSAGKFAVDANS--GAITLMSRVCAAS 175 Query: 434 ERRYVLTVSATDSGGRSDT---AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 E Y L V A S R D +V +++ AN AP F A Y+ +V E +G+ +L Sbjct: 176 EDAYSLQVQA-QSKTRPDLQSYTLVDVSVVPANTAAPAFSQAQYSVNVSETGSVGSVLLQ 234 Query: 491 VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG---- 546 + ATD+D +TY ++ SN F IN +TG + + L+ + SG Sbjct: 235 LQATDAD--CRDAVTYRITGGNSNGL-------FAINRETGELAVVQPLNADVSSGGAAQ 285 Query: 547 YLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGA 605 + LTV A D S + T V ++V++VN PVF Y+ + GT + VGA Sbjct: 286 HTLTVAATDDFASSPRTSTATVLVTVLNVNQYAPVF-AATYSGTFADSVSTGTELVLVGA 344 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP 665 TDAD I Y + F ID +G + + + +++ L A D G P Sbjct: 345 TDAD---GDNIAYAI-TSGNTGNVFAIDAVTGSLTLAAPVCSRTQSSYTLVVTATDDGQP 400 Query: 666 -PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 +S+ +V + N + PVFE +F + +S + G +RA D D Sbjct: 401 EARSAGTVVQLSFSASNAASPVFEQASYSF--TADSSLNAYAGRVRATDAD 449 Score = 128 bits (308), Expect = 3e-27 Identities = 116/413 (28%), Positives = 185/413 (44%), Gaps = 28/413 (6%) Query: 465 YAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQF 524 +APVF ++ E A +G V V ATD D A+I Y + +S + F Sbjct: 6 FAPVFTQDLVRVTLLETASLGDYVTRVEATDQDCADEAEIRYRV---VSGDTTP---PTF 59 Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584 ++ G IT + LD S + L ++A DG LSDT V I+VV+ + + P+F Sbjct: 60 DLDTVGGVITLVRELDFAERSSFSLQLSASDG---DLSDTMYVLINVVETSPDFPLFTSS 116 Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKA 644 YTA++ E A +GT+V+ V AT+ G + + + G F +D SG I Sbjct: 117 RYTADLAESASIGTTVATV-ATNR----TGIASFSITGGN-SAGKFAVDANSGAITLMSR 170 Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 + S + L+ A P S +V + + N + P F + +SE +G+ Sbjct: 171 VCAASEDAYSLQVQAQSKTRPDLQSYTLVDVSVVPANTAAPAFSQAQYSVNVSETGSVGS 230 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP-RKKY 763 + +++A D D V Y I GG+ + F++ G + +V ++ D S ++ Sbjct: 231 VLLQLQATDAD--CRDAVTYRITGGNSNGLFAINRETG--ELAVVQPLNADVSSGGAAQH 286 Query: 764 ELVIRA----ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPA 818 L + A AS P + V + V +VN APV + D G V A Sbjct: 287 TLTVAATDDFASSPRTSTATVLVTVLNVNQYAPVFA--ATYSGTFADSVSTGTELVLVGA 344 Query: 819 YDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 DAD D + Y I SGN N+ ++ TGS+TL+ + + T+ V+ TD Sbjct: 345 TDAD-GDNIAYAITSGNTGNVFAIDAVTGSLTLAAPVCSRTQSSYTLVVTATD 396 Score = 107 bits (256), Expect = 6e-21 Identities = 90/346 (26%), Positives = 151/346 (43%), Gaps = 22/346 (6%) Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638 PVF Q L ++E A +G V++V ATD D I Y + D +F +D GV Sbjct: 8 PVFTQDLVRVTLLETASLGDYVTRVEATDQDCADEAEIRYRVVSGDTTPPTFDLDTVGGV 67 Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698 I + LD ++ L+ A DG S T+ V I + + + P+F S T ++E Sbjct: 68 ITLVRELDFAERSSFSLQLSASDGDL---SDTMYVLINVVETSPDFPLFTSSRYTADLAE 124 Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758 ++ IGTT+ + + + +SI GG+ + F+++ G+ +T++ + Sbjct: 125 SASIGTTVATVATN-----RTGIASFSITGGNSAGKFAVDANSGA-----ITLMSRVCAA 174 Query: 759 PRKKYELVIRAAS---PPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGR 815 Y L ++A S P L + V++ V N AP Q N + + Sbjct: 175 SEDAYSLQVQAQSKTRPDLQSYTLVDVSVVPANTAAPAFSQAQYSVNVSETGSVGSVLLQ 234 Query: 816 VPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNE 875 + A DAD D + YRI GN+ L +N TG + + LN +V + ++T + Sbjct: 235 LQATDADCRDAVTYRITGGNSNGLFAINRETGELAVVQPLNADVSSGGAAQHTLTVAATD 294 Query: 876 IKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLA 921 A S R T +L+ + V + A F + G F D ++ Sbjct: 295 DFAS---SPRTSTATVLVTVLNV---NQYAPVFAATYSGTFADSVS 334 Score = 95.9 bits (228), Expect = 1e-17 Identities = 102/331 (30%), Positives = 155/331 (46%), Gaps = 37/331 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 ++V+ N +P F QY +V E S G+ +L L+ATD D ++A V Y I T Sbjct: 201 VSVVPANTAAPAFSQAQYSVNVSETGSVGSVLLQLQATDADC-RDA-VTYRI---TGGNS 255 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 N A VQ + D SG A++T+ V ATD + S Sbjct: 256 NGLFAINRETGELAVVQPL-NADVSSGG-----------AAQHTLTVAATDDFA--SSPR 301 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 +STAT+ V +++ N P F+ TY+ + + +S V+ + ATDAD G N I YA Sbjct: 302 TSTATVLVTVLNVNQYAPVFA-ATYSGTFADSVSTGTELVL--VGATDAD-GDN--IAYA 355 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP-SRSNTTQLLINIRD 249 I GNT F+ID+++G ++L + SY LV+ A D G P +RS T + ++ Sbjct: 356 ITSGNTGNVFAIDAVTGSLTLAAPVCSRTQSSYTLVVTATDDGQPEARSAGTVVQLSFSA 415 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI 309 N +P F + + S + + + RV+A DAD + +TYT+ N Sbjct: 416 SNAASPVFEQASY--SFTADSSLNAYAGRVRATDAD--CDDSITYTL-----NRNTQFAF 466 Query: 310 TIDPRSGWVYTSGQLDRETQAKYQLLVTATD 340 TI P +G + L ++T Y L ATD Sbjct: 467 TIHPTTGVITVVAPLTQDT--PYVLDAVATD 495 >UniRef50_UPI000065EA2C Cluster: Homolog of Homo sapiens "Protocadherin LKC precursor; n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens "Protocadherin LKC precursor - Takifugu rubripes Length = 1174 Score = 185 bits (450), Expect = 2e-44 Identities = 166/544 (30%), Positives = 260/544 (47%), Gaps = 47/544 (8%) Query: 104 SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI 163 +LD E + + V A D+ + STAT+ ++IID NDN P+F + TY +SV E Sbjct: 401 NLDYEVKQQMILKVVAIDEGE---SKFRSTATVTISIIDTNDNSPKFPKDTYKLSVPEHA 457 Query: 164 SVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLV-KTLDYEQVRS 222 S + VIA I A D D IRY ++ + F +D+ +G V + TL +VRS Sbjct: 458 S--NGMVIANITAEDPDTMDRGNIRYRLLPDSILQYFGVDNRTGAVFVKNSTLLDREVRS 515 Query: 223 -YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA 281 + + ++A+D S ++ +T+L I + D+ND P +Q V E G ++++A Sbjct: 516 LHSVTLQARD--SEDKTGSTELEITVTDINDQYPVINRDSYQVFVKEG---GDFNLKIEA 570 Query: 282 YDAD--EGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE-----TQAKYQL 334 DAD +N+++ Y ++ Y+ N TIDP SG + SG LDRE Q + +L Sbjct: 571 TDADMPNTLNSQIVYAISPSTYSDN----FTIDPNSGVLTNSGNLDREFLDSKLQGRVEL 626 Query: 335 LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394 +VTATD G PP S+ T F Y + E + G V ++ A D D Sbjct: 627 IVTATDKGTPPLSSNVTVIVNIEDINDNIPQFSNASYTFSVKEGQ-KGAYVGSVYAEDLD 685 Query: 395 ---EDNRLHYEITGGNTRGRFSITS--QNGRGL-----ITVAQPLDFKQERRYVLTVSAT 444 E NR+ + I G++ G F I S ++GRG + LD++ R L + A Sbjct: 686 QTTEFNRISFSIVDGSS-GSFIIRSFAEDGRGYRGDIRVDPDVELDYESIRNQTLRIEAA 744 Query: 445 DSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504 D RS A+V++N+ D N+ P F SV E+ TV +A D D N + Sbjct: 745 DLEQRSAEAVVKVNVLDVNDERPEF-GPIEPVSVKENTNNTETVGKFTAYDRDG--NHSL 801 Query: 505 TYSLSSE--ISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD----GGV 558 Y L S N+++ + + + N L+D E L+ D G Sbjct: 802 LYELESIQCKCNDSMTSCNSFILDTTGEVRVNPNDLVDYEKCDQVLIEAQVVDQFTEKGE 861 Query: 559 PSLSDTTDVEISVVDVNDNEP--VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI 616 + + T + I++ DVNDN P ++ ++ + E A GTSV+ V ATD D GLN ++ Sbjct: 862 NNSAKTGLMVINIEDVNDNAPEFIYSDSVFVV-VSESASKGTSVAGVTATDRDSGLNRQM 920 Query: 617 HYEL 620 +++ Sbjct: 921 EFKV 924 Score = 159 bits (386), Expect = 1e-36 Identities = 188/725 (25%), Positives = 309/725 (42%), Gaps = 86/725 (11%) Query: 178 DADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRL-VIRAQDGGSPS 236 DA N + + +IG N+ FS++ +G V + +TLD E + Y V + Q Sbjct: 8 DASDPENDPLTFELIGPNSGF-FSVEQGTGRVFIDQTLDREWIIYYVCGVFQIQ------ 60 Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 L I +++ NDN P F S + E+ +G S+ A D D + Y++ Sbjct: 61 ----RDLTIFLKEANDNKPIFQQSSYDTKTPEDTAVGASLFTALAEDRDLSNAGAVRYSI 116 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDPP-------RSA 348 + + V+L I+ SG V+ +G L+ T + YQL + ATDGG S Sbjct: 117 DEVIPSSGVNL-FRIN-ASGVVWLNGSLNYNTLSTFYQLKINATDGGGRCFYNETNFWSN 174 Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGG 406 F+ Y + E+ P V T+ A D D+ ++ + Y I G Sbjct: 175 VVFSFITIVDVPDLNPMFLGLPYVASVEENSPVNHSVFTVNAFDQDKGINDAIIYSIEGS 234 Query: 407 NTRGRFSITSQNGRGLITVAQPLDFKQERRYV-LTVSATDSGG------RSDTAMVQINI 459 T G F I+S + G+I+VA P+D + V LTV AT+S + T VQINI Sbjct: 235 TTEGLFKISSDD--GVISVAGPIDREVTGDTVNLTVKATESKQDVHGVFANTTVQVQINI 292 Query: 460 TDANNYAPVF--------ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE 511 D N+ P F + +T V E +G+ + ++ D D + IT + + Sbjct: 293 QDVNDNGPEFYKCGFYCVNTSHFTGEVLEHF-LGSISINMTVKDPDRVSRSTITRTPEPK 351 Query: 512 I-------------SNEAVAHHDQQ--FVINPQTGAITTNKLL--------DRETMSGYL 548 + + + + + F + P++ N L D E + Sbjct: 352 VWLRVTLTIFPKTPRTQLILEGEDKDVFSVQPESLVSGINVQLQVKQPQNLDYEVKQQMI 411 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 L V A D G T V IS++D NDN P F + Y ++ E A G ++ + A D Sbjct: 412 LKVVAIDEGESKFRSTATVTISIIDTNDNSPKFPKDTYKLSVPEHASNGMVIANITAEDP 471 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGV--IRTNKALDRESVATHDLKAVAIDGGTPP 666 D G I Y L P D F +D +G ++ + LDRE + H + A D + Sbjct: 472 DTMDRGNIRYRLLP-DSILQYFGVDNRTGAVFVKNSTLLDREVRSLHSVTLQARD--SED 528 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 ++ + + I + DIND PV D ++ E I A P+ N+ + Y+I Sbjct: 529 KTGSTELEITVTDINDQYPVINRDSYQVFVKEGGDFNLKIEATDADMPNT-LNSQIVYAI 587 Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYE----SPRKKYELVIRA---ASPPLWNDVR 779 S++F+++ G L +LD E + + EL++ A +PPL ++V Sbjct: 588 SPSTYSDNFTIDPNSG----VLTNSGNLDREFLDSKLQGRVELIVTATDKGTPPLSSNVT 643 Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVT---DKLQYRILSGNN 836 V + + D+NDN P + F + K+ G V A D D T +++ + I+ G++ Sbjct: 644 VIVNIEDINDNIPQFSNASYTF-SVKEGQKGAYVGSVYAEDLDQTTEFNRISFSIVDGSS 702 Query: 837 ANLIL 841 + I+ Sbjct: 703 GSFII 707 Score = 149 bits (360), Expect = 1e-33 Identities = 172/604 (28%), Positives = 267/604 (44%), Gaps = 80/604 (13%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+++D ND+SP F Y+ SV E AS+G + + A D D + Y L Sbjct: 432 ISIIDTNDNSPKFPKDTYKLSVPEHASNGMVIANITAEDPDTMDRGNIRYR--------L 483 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS--LDREKVARYTVLVKATDQASPVSD 128 P+ + F +D R+GA+ + S LDRE + ++V ++A D D Sbjct: 484 LPDS-----------ILQYFGVDNRTGAVFVKNSTLLDREVRSLHSVTLQARDS----ED 528 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG--ANSA 186 + ST + + + D ND YP + +Y V V E KI+ATDAD+ NS Sbjct: 529 KTGSTE-LEITVTDINDQYPVINRDSYQVFVKEGGDFN-----LKIEATDADMPNTLNSQ 582 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-----YRLVIRAQDGGSPSRSNTT 241 I YAI F+ID SG ++ LD E + S L++ A D G+P S+ Sbjct: 583 IVYAISPSTYSDNFTIDPNSGVLTNSGNLDREFLDSKLQGRVELIVTATDKGTPPLSSNV 642 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAE-LTYTMTDKD 300 +++NI D+NDN P+F + + SV E Y + V A D D+ +++++ D Sbjct: 643 TVIVNIEDINDNIPQFSNASYTFSVKEGQKGAY-VGSVYAEDLDQTTEFNRISFSIVDGS 701 Query: 301 YTGNVDLPITIDPRSGW-----VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355 +G+ + + G+ V +LD E+ L + A D RSA A Sbjct: 702 -SGSFIIRSFAEDGRGYRGDIRVDPDVELDYESIRNQTLRIEAADLEQ--RSAEAVVKVN 758 Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSIT 415 F P + V + E+ V TA D D ++ L YE+ + S+T Sbjct: 759 VLDVNDERPEFGPIE-PVSVKENTNNTETVGKFTAYDRDGNHSLLYELESIQCKCNDSMT 817 Query: 416 SQNGRGLITVAQP-------LDFKQERRYVLTVSATDS------GGRSDTAMVQINITDA 462 S N L T + +D+++ + ++ D + T ++ INI D Sbjct: 818 SCNSFILDTTGEVRVNPNDLVDYEKCDQVLIEAQVVDQFTEKGENNSAKTGLMVINIEDV 877 Query: 463 NNYAPVFENAPYTASVF----EDAPIGTTVLVVSATDSDVGINAQITYSLSS---EISNE 515 N+ AP F Y+ SVF E A GT+V V+ATD D G+N Q+ + +++ +N+ Sbjct: 878 NDNAPEFI---YSDSVFVVVSESASKGTSVAGVTATDRDSGLNRQMEFKVTAVQFRDNND 934 Query: 516 AVAHHDQQF-VINPQ-----TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEI 569 F I Q G I T + LD + Y++TVTA D G LS T++EI Sbjct: 935 QTNTMRILFEAITTQQKDSYVGIIQTTEGLDMKLKGKYVVTVTATDTG--GLSTNTELEI 992 Query: 570 SVVD 573 VD Sbjct: 993 FTVD 996 Score = 136 bits (328), Expect = 1e-29 Identities = 136/499 (27%), Positives = 219/499 (43%), Gaps = 48/499 (9%) Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383 LD E + + L V A D G+ +TAT F Y++ + E G Sbjct: 402 LDYEVKQQMILKVVAIDEGESKFRSTATVTISIIDTNDNSPKFPKDTYKLSVPEHASNGM 461 Query: 384 PVVTLTATDADEDNR--LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441 + +TA D D +R + Y + + F + ++ G + + LD + + +T+ Sbjct: 462 VIANITAEDPDTMDRGNIRYRLLPDSILQYFGVDNRTGAVFVKNSTLLDREVRSLHSVTL 521 Query: 442 SATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG-- 499 A DS ++ + ++I +TD N+ PV Y V E G L + ATD+D+ Sbjct: 522 QARDSEDKTGSTELEITVTDINDQYPVINRDSYQVFVKEG---GDFNLKIEATDADMPNT 578 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL-----LTVTAR 554 +N+QI Y++S + F I+P +G +T + LDRE + L L VTA Sbjct: 579 LNSQIVYAISPST-------YSDNFTIDPNSGVLTNSGNLDREFLDSKLQGRVELIVTAT 631 Query: 555 DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN- 613 D G P LS V +++ D+NDN P F YT ++ E G V V A D D Sbjct: 632 DKGTPPLSSNVTVIVNIEDINDNIPQFSNASYTFSVKEGQK-GAYVGSVYAEDLDQTTEF 690 Query: 614 GRIHYELDPKDREEGSFVIDPAS-------GVIRTNK--ALDRESVATHDLKAVAIDGGT 664 RI + + D GSF+I + G IR + LD ES+ L+ A D Sbjct: 691 NRISFSI--VDGSSGSFIIRSFAEDGRGYRGDIRVDPDVELDYESIRNQTLRIEAAD--L 746 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH- 723 +S+ +V + + D+ND P F + EN+ T+G+ A+D D G +++++ Sbjct: 747 EQRSAEAVVKVNVLDVNDERPEF-GPIEPVSVKENTNNTETVGKFTAYDRD-GNHSLLYE 804 Query: 724 ---YSIKGGDDS---NSFSLETRQGSDKAELVTMVDLDY-ESPRKKYELVIRAASPPLWN 776 K D NSF L+T G + +VD + + + ++V + N Sbjct: 805 LESIQCKCNDSMTSCNSFILDTT-GEVRVNPNDLVDYEKCDQVLIEAQVVDQFTEKGENN 863 Query: 777 DVRVEILVT---DVNDNAP 792 + ++V DVNDNAP Sbjct: 864 SAKTGLMVINIEDVNDNAP 882 Score = 123 bits (296), Expect = 8e-26 Identities = 142/540 (26%), Positives = 235/540 (43%), Gaps = 41/540 (7%) Query: 213 KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI 272 + LDYE + L + A D G +T + I+I D NDN+P+F ++ SV E+ Sbjct: 400 QNLDYEVKQQMILKVVAIDEGESKFRSTATVTISIIDTNDNSPKFPKDTYKLSVPEHASN 459 Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY--TSGQLDRETQA 330 G I + A D D + Y + ++ +D R+G V+ S LDRE ++ Sbjct: 460 GMVIANITAEDPDTMDRGNIRYRL----LPDSILQYFGVDNRTGAVFVKNSTLLDREVRS 515 Query: 331 KYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTA 390 + + + A D D ++ + Y+V + E G + + A Sbjct: 516 LHSVTLQARDSED--KTGSTELEITVTDINDQYPVINRDSYQVFVKEG---GDFNLKIEA 570 Query: 391 TDADEDNRLHYEITGGNTRGRFS--ITSQNGRGLITVA-----QPLDFKQERRYVLTVSA 443 TDAD N L+ +I + +S T G++T + + LD K + R L V+A Sbjct: 571 TDADMPNTLNSQIVYAISPSTYSDNFTIDPNSGVLTNSGNLDREFLDSKLQGRVELIVTA 630 Query: 444 TDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501 TD G S V +NI D N+ P F NA YT SV ++ G V V A D D Sbjct: 631 TDKGTPPLSSNVTVIVNIEDINDNIPQFSNASYTFSV-KEGQKGAYVGSVYAEDLDQTTE 689 Query: 502 -AQITYSLSSEISNEAVAHHDQQFVINPQTG-AITTNKLLDRETMSGYLLTVTARDGGVP 559 +I++S+ S + + + + + LD E++ L + A D + Sbjct: 690 FNRISFSIVDGSSGSFIIRSFAEDGRGYRGDIRVDPDVELDYESIRNQTLRIEAAD--LE 747 Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619 S V+++V+DVND P F + ++ E+ +V + A D D N + YE Sbjct: 748 QRSAEAVVKVNVLDVNDERPEF-GPIEPVSVKENTNNTETVGKFTAYDRDG--NHSLLYE 804 Query: 620 LDP---KDREE----GSFVIDPASGV-IRTNKALDRESVATHDLKAVAID----GGTPPQ 667 L+ K + SF++D V + N +D E ++A +D G Sbjct: 805 LESIQCKCNDSMTSCNSFILDTTGEVRVNPNDLVDYEKCDQVLIEAQVVDQFTEKGENNS 864 Query: 668 SSTVIVHIKIEDINDSPPVF-ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 + T ++ I IED+ND+ P F SD + +SE++ GT++ + A D D G N + + + Sbjct: 865 AKTGLMVINIEDVNDNAPEFIYSDSVFVVVSESASKGTSVAGVTATDRDSGLNRQMEFKV 924 Score = 101 bits (241), Expect = 4e-19 Identities = 117/420 (27%), Positives = 186/420 (44%), Gaps = 42/420 (10%) Query: 382 GTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441 G + A+D + D L +E+ G N+ G FS+ + G G + + Q LD + YV V Sbjct: 1 GEVAFVIDASDPENDP-LTFELIGPNS-GFFSV--EQGTGRVFIDQTLDREWIIYYVCGV 56 Query: 442 SATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN 501 + I + +AN+ P+F+ + Y ED +G ++ A D D+ Sbjct: 57 FQIQRD-------LTIFLKEANDNKPIFQQSSYDTKTPEDTAVGASLFTALAEDRDLSNA 109 Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG-YLLTVTARDGGVPS 560 + YS+ I + V F IN +G + N L+ T+S Y L + A DGG Sbjct: 110 GAVRYSIDEVIPSSGV----NLFRIN-ASGVVWLNGSLNYNTLSTFYQLKINATDGGGRC 164 Query: 561 LSDTTDV-------EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613 + T+ I++VDV D P+F Y A++ E++ V SV V A D D G+N Sbjct: 165 FYNETNFWSNVVFSFITIVDVPDLNPMFLGLPYVASVEENSPVNHSVFTVNAFDQDKGIN 224 Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA-THDLKAVAIDGGTPPQ----S 668 I Y ++ EG F I GVI +DRE T +L A + + Sbjct: 225 DAIIYSIE-GSTTEGLFKISSDDGVISVAGPIDREVTGDTVNLTVKATESKQDVHGVFAN 283 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 +TV V I I+D+ND+ P F C FY S GE+ H + ++ ++K Sbjct: 284 TTVQVQINIQDVNDNGPEFYK-C-GFYCVNTSHF---TGEVLEHFLG---SISINMTVK- 334 Query: 729 GDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVN 788 D S S TR K L + + ++PR +L++ +++ V+ E LV+ +N Sbjct: 335 DPDRVSRSTITRTPEPKVWLRVTLTIFPKTPRT--QLILEGEDKDVFS-VQPESLVSGIN 391 Score = 90.6 bits (215), Expect = 5e-16 Identities = 88/319 (27%), Positives = 141/319 (44%), Gaps = 41/319 (12%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 + ND+ P+F+ Y+ E + G ++ T A D+D+ V Y+I D + P Sbjct: 69 EANDNKPIFQQSSYDTKTPEDTAVGASLFTALAEDRDLSNAGAVRYSI-----DEVIPSS 123 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVAR-YTVLVKATDQASPV----SDR 129 ++FRI+ SG + SL+ ++ Y + + ATD ++ Sbjct: 124 GV-----------NLFRINA-SGVVWLNGSLNYNTLSTFYQLKINATDGGGRCFYNETNF 171 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 S+ + I+D D P F Y SV+E+ V N + + A D D G N AI Y Sbjct: 172 WSNVVFSFITIVDVPDLNPMFLGLPYVASVEENSPV--NHSVFTVNAFDQDKGINDAIIY 229 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVR-SYRLVIRA----QDGGSPSRSNTTQLL 244 +I G T+ F I S G +S+ +D E + L ++A QD + T Q+ Sbjct: 230 SIEGSTTEGLFKISSDDGVISVAGPIDREVTGDTVNLTVKATESKQDVHGVFANTTVQVQ 289 Query: 245 INIRDVNDNAPRFY--------TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 INI+DVNDN P FY TS F V E+ +G + + D D + +T T Sbjct: 290 INIQDVNDNGPEFYKCGFYCVNTSHFTGEVLEHF-LGSISINMTVKDPDRVSRSTITRTP 348 Query: 297 TDKDYTGNVDLPITIDPRS 315 K + + + +TI P++ Sbjct: 349 EPKVW---LRVTLTIFPKT 364 Score = 75.8 bits (178), Expect = 2e-11 Identities = 67/209 (32%), Positives = 96/209 (45%), Gaps = 19/209 (9%) Query: 144 NDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI---IGGNTQMQF 200 NDN P F + +Y ED +V + A A D D+ A+RY+I I + F Sbjct: 71 NDNKPIFQQSSYDTKTPEDTAVGASLFTAL--AEDRDLSNAGAVRYSIDEVIPSSGVNLF 128 Query: 201 SIDSLSGDVSLVKTLDYEQVRS-YRLVIRAQDGGSPSRSNTTQL-------LINIRDVND 252 I++ SG V L +L+Y + + Y+L I A DGG N T I I DV D Sbjct: 129 RINA-SGVVWLNGSLNYNTLSTFYQLKINATDGGGRCFYNETNFWSNVVFSFITIVDVPD 187 Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312 P F + SV EN P+ +S+ V A+D D+G+N + Y++ G I Sbjct: 188 LNPMFLGLPYVASVEENSPVNHSVFTVNAFDQDKGINDAIIYSIEGSTTEG----LFKIS 243 Query: 313 PRSGWVYTSGQLDRE-TQAKYQLLVTATD 340 G + +G +DRE T L V AT+ Sbjct: 244 SDDGVISVAGPIDREVTGDTVNLTVKATE 272 Score = 52.4 bits (120), Expect = 2e-04 Identities = 43/142 (30%), Positives = 63/142 (44%), Gaps = 21/142 (14%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I ++D D +P+F Y ASV E + +V T+ A DQD G N + Y+IE T + L Sbjct: 180 ITIVDVPDLNPMFLGLPYVASVEENSPVNHSVFTVNAFDQDKGINDAIIYSIEGSTTEGL 239 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA-RYTVLVKATDQASPVSDR 129 F+I G + +DRE + VKAT+ V Sbjct: 240 -------------------FKISSDDGVISVAGPIDREVTGDTVNLTVKATESKQDVHGV 280 Query: 130 LSSTAT-IHVNIIDDNDNYPQF 150 ++T + +NI D NDN P+F Sbjct: 281 FANTTVQVQINIQDVNDNGPEF 302 Score = 51.2 bits (117), Expect = 4e-04 Identities = 48/172 (27%), Positives = 70/172 (40%), Gaps = 13/172 (7%) Query: 11 INVLDCNDHSPVF-EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 IN+ D ND++P F V E AS GT+V + ATD+D G N ++E+ + V Sbjct: 872 INIEDVNDNAPEFIYSDSVFVVVSESASKGTSVAGVTATDRDSGLNRQMEFKVTAVQFRD 931 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N + Q + D G + T LD + +Y V V ATD Sbjct: 932 NNDQTNTMRILFEAITTQ---QKDSYVGIIQTTEGLDMKLKGKYVVTVTATDTGG----- 983 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181 LS+ + + +D+ E +T S E D + A AT A V Sbjct: 984 LSTNTELEIFTVDETYKV----ELEFTSSEQEVEQKLDEIINALTAATKAAV 1031 >UniRef50_Q9UN73-2 Cluster: Isoform 2 of Q9UN73 ; n=6; Mammalia|Rep: Isoform 2 of Q9UN73 - Homo sapiens (Human) Length = 686 Score = 184 bits (447), Expect = 4e-44 Identities = 130/419 (31%), Positives = 195/419 (46%), Gaps = 24/419 (5%) Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQ-AYDADEGVNAELTYTMTDKDYTG 303 + +RD+NDN P F + + E+ + S+ ++ A DAD G N+ LTY ++ +Y G Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYES-RLPDSVFPLEGASDADVGSNSILTYKLSSSEYFG 179 Query: 304 NVDLPITIDPRSG-WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 +D+ I D + LDRE + L +TATDGG P + T Sbjct: 180 -LDVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDN 238 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYE---ITGGNTRGRFSITSQ 417 F +YEV + E+ GT V+ L A+D DE + + Y + FSI Sbjct: 239 APTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRN 298 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYT 475 G I + LDF+QE Y + + ATD G + V + I D N+ P + Sbjct: 299 TGE--IVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLS 356 Query: 476 ASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITT 535 V EDA GT + ++S D D G N Q+ SL+ + + V+ + ++ Sbjct: 357 LPVREDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYY-------SLVL 409 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 + LDRE++S Y L VTARDGG PSL T + + V D+NDN P F Q YT + E+ Sbjct: 410 DSALDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNP 469 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPK---DREEGSFV-IDPASGVIRTNKALDRESV 650 G + V A DAD N + Y L + +R S++ + SG + + LD E + Sbjct: 470 PGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEEL 528 Score = 178 bits (433), Expect = 2e-42 Identities = 130/468 (27%), Positives = 222/468 (47%), Gaps = 21/468 (4%) Query: 87 QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146 +D+ ++ ++G L + +DRE++ + + + + DR + V + D NDN Sbjct: 72 EDLLEVNLQNGILFVNSRIDREELCGRSA--ECSIHLEVIVDRPLQVFHVDVEVRDINDN 129 Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI-----IGGNTQMQFS 201 P F + V + E S + V A+DADVG+NS + Y + G + ++ S Sbjct: 130 PPLFPVEEQRVLIYE--SRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKIN-S 186 Query: 202 IDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261 D+ + L K+LD E+ ++ L + A DGG P + T QLL+ + DVNDNAP F S Sbjct: 187 DDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSE 246 Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321 ++ + EN G +++R+ A D DEG N ++Y+ +D +ID +G + Sbjct: 247 YEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVID-HFSIDRNTGEIVIR 305 Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381 G LD E + Y++L+ ATD G PP + T + + ED Sbjct: 306 GNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQF 365 Query: 382 GTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL 439 GT + ++ D D + +++ +T + + T +N L+ + LD + Y L Sbjct: 366 GTVIALISVNDLDSGANGQVNCSLT-PHVPFKLVSTFKNYYSLV-LDSALDRESVSAYEL 423 Query: 440 TVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD 497 V+A D G S TA + + + D N+ AP F YT V E+ P G + VSA D+D Sbjct: 424 VVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDAD 483 Query: 498 VGINAQITYSL-SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 NA ++YSL + A++ + ++ ++G + + LD E + Sbjct: 484 AQENALVSYSLVERRVGERALSSY---ISVHAESGKVYALQPLDHEEL 528 Score = 169 bits (412), Expect = 7e-40 Identities = 108/343 (31%), Positives = 178/343 (51%), Gaps = 11/343 (3%) Query: 390 ATDAD--EDNRLHYEITGGNTRGR-FSITSQNGRGL-ITVAQPLDFKQERRYVLTVSATD 445 A+DAD ++ L Y+++ G I S + + + + + + LD ++ + L ++ATD Sbjct: 157 ASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATD 216 Query: 446 SGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQ 503 G T VQ+ +T D N+ AP FE + Y +FE+A GTTV+ ++A+D D G N Sbjct: 217 GGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGA 276 Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSD 563 I+YS +S ++ + H F I+ TG I LD E + Y + + A D G P ++ Sbjct: 277 ISYSFNSLVAAMVIDH----FSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAG 332 Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK 623 V + ++D NDN P + + EDA GT ++ + D D G NG+++ L P Sbjct: 333 HCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLTPH 392 Query: 624 DREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS 683 + ++ + ALDRESV+ ++L A DGG+P +T + +++ D+ND+ Sbjct: 393 VPFKLVSTFKNYYSLV-LDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDN 451 Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 P F T ++ EN+P G I + A D D NA+V YS+ Sbjct: 452 APAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494 Score = 163 bits (395), Expect = 8e-38 Identities = 109/321 (33%), Positives = 160/321 (49%), Gaps = 28/321 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND++P FE +YE + E A +GTTV+ L A+D+D G N + Y+ + A Sbjct: 230 VTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVA--- 286 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 V D F ID +G ++ R +LD E+ Y +L+ ATD+ P + Sbjct: 287 -------------AMVIDHFSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHP---PM 330 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + T+ V I+D NDN P+ + + ++ V ED VIA I D D GAN + + Sbjct: 331 AGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQF--GTVIALISVNDLDSGANGQVNCS 388 Query: 191 IIGGNTQMQFS-IDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 + + F + + SLV LD E V +Y LV+ A+DGGSPS T L + + Sbjct: 389 L---TPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEV 445 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN-VD 306 D+NDNAP F + V EN P G I V A DAD NA ++Y++ ++ + Sbjct: 446 ADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALS 505 Query: 307 LPITIDPRSGWVYTSGQLDRE 327 I++ SG VY LD E Sbjct: 506 SYISVHAESGKVYALQPLDHE 526 Score = 151 bits (366), Expect = 3e-34 Identities = 114/345 (33%), Positives = 162/345 (46%), Gaps = 17/345 (4%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE--I 512 V + + D N+ P+F ++E + + A+D+DVG N+ +TY LSS Sbjct: 119 VDVEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYF 178 Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572 + + D N Q G + K LDRE + L +TA DGG P L+ T + ++V+ Sbjct: 179 GLDVKINSDD----NKQIGLLL-KKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVL 233 Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDP--KDREEGSF 630 DVNDN P F+Q Y I E+A GT+V ++ A+D D G NG I Y + F Sbjct: 234 DVNDNAPTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHF 293 Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESD 690 ID +G I LD E + + A D G PP + V ++I D ND+ P Sbjct: 294 SIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALT 353 Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750 L+ + E++ GT I I +D D G N V+ S+ F L + LV Sbjct: 354 SLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSL---TPHVPFKL-VSTFKNYYSLVL 409 Query: 751 MVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792 LD ES YELV+ A SP LW + + V D+NDNAP Sbjct: 410 DSALDRESV-SAYELVVTARDGGSPSLWATASLSVEVADMNDNAP 453 Score = 116 bits (278), Expect = 1e-23 Identities = 96/326 (29%), Positives = 145/326 (44%), Gaps = 21/326 (6%) Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 SV E+A GT V ++ D+G+ L + A + +N Q G + N Sbjct: 34 SVPEEAKHGTFVGRIA---QDLGLELA---ELVPRLFRMASKDREDLLEVNLQNGILFVN 87 Query: 537 KLLDRETMSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 +DRE + G + + V V++ V D+NDN P+F + I E L Sbjct: 88 SRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLFPVEEQRVLIYESRL 147 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI---DPASGVIRTNKALDRESVAT 652 + GA+DADVG N + Y+L + I D + K+LDRE Sbjct: 148 PDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIGLLLKKSLDREEAPA 207 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAH 712 H+L A DGG P + TV + + + D+ND+ P FE I EN+ GTT+ + A Sbjct: 208 HNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIRLNAS 267 Query: 713 DPDEGPNAVVHY---SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA 769 D DEG N + Y S+ + FS++ G E+V +LD+E Y+++I A Sbjct: 268 DRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG----EIVIRGNLDFEQ-ENLYKILIDA 322 Query: 770 AS---PPLWNDVRVEILVTDVNDNAP 792 PP+ V + + D NDN P Sbjct: 323 TDKGHPPMAGHCTVLVRILDKNDNVP 348 Score = 60.5 bits (140), Expect = 7e-07 Identities = 57/226 (25%), Positives = 106/226 (46%), Gaps = 16/226 (7%) Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIH--YELDPKDREEGSFVIDPASGVIRTNKALD 646 ++ E+A GT V ++ A D + L + + + KDRE+ ++ +G++ N +D Sbjct: 34 SVPEEAKHGTFVGRI-AQDLGLELAELVPRLFRMASKDRED-LLEVNLQNGILFVNSRID 91 Query: 647 RESVATHDLK-AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 RE + + ++ ++ V +++ DIND+PP+F + I E+ + Sbjct: 92 REELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLFPVEEQRVLIYESRLPDSV 151 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV---DLDYE-SPRK 761 A D D G N+++ Y + S F L+ + SD + + ++ LD E +P Sbjct: 152 FPLEGASDADVGSNSILTYKLSS---SEYFGLDVKINSDDNKQIGLLLKKSLDREEAPAH 208 Query: 762 KYELVIR-AASPPLWNDVRVEILVTDVNDNAPVMK--DFQI-IFNN 803 L P L V++ + V DVNDNAP + ++++ IF N Sbjct: 209 NLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFEN 254 >UniRef50_UPI0000E486F2 Cluster: PREDICTED: hypothetical protein; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: hypothetical protein - Strongylocentrotus purpuratus Length = 1139 Score = 182 bits (443), Expect = 1e-43 Identities = 166/558 (29%), Positives = 259/558 (46%), Gaps = 35/558 (6%) Query: 119 ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178 A Q+S R +STA +H+ + D N+ P F Y ++ ED V N I +++A D Sbjct: 163 AIAQSSSGGVRSTSTAEVHIVVQDVNEQPPLFLRGNYAATISEDYPVFSN--IIQVEAHD 220 Query: 179 ADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD------G 232 +D G N + Y+ QF+I + +G VSL + LD++Q SY L + A+D G Sbjct: 221 SDSGTNGEVYYSF--RQQTDQFAIHTTTGVVSLTRPLDFDQQSSYTLTVVAKDRGFTPYG 278 Query: 233 GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292 G P S QL I ++ VN ++P Q +VS N IG V D D GVN E+ Sbjct: 279 GLPLTS-PVQLRIYVQQVNKHSPEIRIEK-QPTVSRNSEIGTVFAVVGVTDEDGGVNGEI 336 Query: 293 -TYTMTDKDYTGNVDLPITIDP-RSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350 + D D G + + P R L + + V A+D G P+S + Sbjct: 337 AALDIIDGDPGGFFRVQPSPSPGRYQLQIARSLLSSSLPHAFNVTVAASDRGLSPKSTSL 396 Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG 410 F + + E P TP +++ A + Y IT + Sbjct: 397 VVGVVLDGAMNYEAYFTNDFFNTTINELMPVNTPFLSVAPRSAVGNTGFSYVITDSSL-- 454 Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPV 468 FSI + G+++VA LD + Y TV+ ++ + +DT +V I ++DAN+ P Sbjct: 455 PFSIGTHT--GMLSVAFDLDRETTPEYEFTVAVRNAKQQTIADTRVVVI-LSDANDNNPS 511 Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528 FE YT V E+ P + VLVV A+D D+G N I+YS++ + AV F I+ Sbjct: 512 FEEEIYTVEVEENRPAHSQVLVVRASDPDLGENGFISYSIA---NLNAV-----PFTIDH 563 Query: 529 QTGAITTNKLLDRETM-SGYLLTVTARDGGVPSLSDTTDVEI-SVVDVNDNEPVFKQQLY 586 +TG+I T+K+LD ETM Y L V A D G P + V I +++++NDN P F++ Sbjct: 564 ETGSINTSKVLDYETMRHQYRLRVRASDWGSPFRREAKAVVIVNLINLNDNRPKFEKINC 623 Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALD 646 I + G +++ + A D D R Y + + + F I+P SG + ++ + Sbjct: 624 VGAIAKSFPSGRAIALISALDFD---ENRPRYWITSGNVND-LFSINPQSGNLTLSRPVA 679 Query: 647 RESVATHDLKAVAIDGGT 664 + L+ A DG T Sbjct: 680 DSDPLFYSLRIEARDGPT 697 Score = 179 bits (435), Expect = 1e-42 Identities = 124/342 (36%), Positives = 178/342 (52%), Gaps = 22/342 (6%) Query: 462 ANNYAPVFENAPYTA-SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520 +N + P FE T+ V EDAP+G TVL V+A D D G N ++ Y++S N+ +H Sbjct: 763 SNVHEPEFETGFRTSVEVPEDAPVGGTVLTVNANDLDHGFNGKLLYAISD--GNDK-SHF 819 Query: 521 DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580 F +TG + LDRET S Y +TV D G P + + + I++ DVNDN P Sbjct: 820 QMDF----ETGELKVLMPLDRETQSTYDVTVKISDMGKPQHTRKSPLTITLTDVNDNAPQ 875 Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIR 640 F + Y I EDA VG S V A+D D G N + Y + + SF ID +G + Sbjct: 876 FDLKQYDVAIPEDAEVGLSFLAVHASDRDEGRNQEVRYSI---ISDSPSFDIDIITGELS 932 Query: 641 TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700 LDRE+ H+++ A D P SS+VIV + ++DIND+PP I E+ Sbjct: 933 VAGPLDRETNPVHEIRVQATDLSDSPLSSSVIVRVSLDDINDNPPRCLLPEYKVKIREDL 992 Query: 701 PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760 P G + ++AHDPD PN V Y + S+ FS++T G+ LV M LDYE Sbjct: 993 PTGAAVLSVQAHDPDNPPNGTVRYRL-DTSGSSKFSIDTDYGT--LRLVEM--LDYE-VT 1046 Query: 761 KKYELVIRAAS---PPLWNDVRVEILVTDVNDN--APVMKDF 797 + YE+V+ P + + R+ + V DVN+N APV ++ Sbjct: 1047 QLYEIVVAIRDEGIPAMSSTCRIVVEVVDVNENTHAPVFPNY 1088 Score = 176 bits (429), Expect = 6e-42 Identities = 140/531 (26%), Positives = 243/531 (45%), Gaps = 45/531 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +N+++ ND+ P FE ++ + SG + + A D D + + + ++ Sbjct: 606 VNLINLNDNRPKFEKINCVGAIAKSFPSGRAIALISALDFDENRPRYWITSGNVNDLFSI 665 Query: 71 NPEDAXXXXXXXXXXVQDVF---RIDGRSG-----------ALLTRASLDREKVAR-YTV 115 NP+ +F RI+ R G + A+ + AR V Sbjct: 666 NPQSGNLTLSRPVADSDPLFYSLRIEARDGPTSVSYMRTNMTITNNANPSPQAHARGLKV 725 Query: 116 LVKATDQASPVSD-----RLSSTATIHV-----NIIDDNDNYPQFSEKTYT-VSVDEDIS 164 + TD A + + S+ H+ + N + P+F T V V ED Sbjct: 726 TCQETDVAEEIEELYGQLEASNQEVEHLPPNYAELYSSNVHEPEFETGFRTSVEVPEDAP 785 Query: 165 VTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYR 224 V + + A D D G N + YAI GN + F +D +G++ ++ LD E +Y Sbjct: 786 V--GGTVLTVNANDLDHGFNGKLLYAISDGNDKSHFQMDFETGELKVLMPLDRETQSTYD 843 Query: 225 LVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA 284 + ++ D G P + + L I + DVNDNAP+F + ++ E+ +G S + V A D Sbjct: 844 VTVKISDMGKPQHTRKSPLTITLTDVNDNAPQFDLKQYDVAIPEDAEVGLSFLAVHASDR 903 Query: 285 DEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDP 344 DEG N E+ Y++ + ++D+ IT G + +G LDRET +++ V ATD D Sbjct: 904 DEGRNQEVRYSIISDSPSFDIDI-IT-----GELSVAGPLDRETNPVHEIRVQATDLSDS 957 Query: 345 PRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYE 402 P S++ + +Y+V++ ED P G V+++ A D D + + Y Sbjct: 958 PLSSSVIVRVSLDDINDNPPRCLLPEYKVKIREDLPTGAAVLSVQAHDPDNPPNGTVRYR 1017 Query: 403 I-TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINI 459 + T G++ +FSI + G + + + LD++ + Y + V+ D G S T + + + Sbjct: 1018 LDTSGSS--KFSIDTD--YGTLRLVEMLDYEVTQLYEIVVAIRDEGIPAMSSTCRIVVEV 1073 Query: 460 TDA--NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508 D N +APVF N T SV E T V+ +SA D D+GI+ +++Y++ Sbjct: 1074 VDVNENTHAPVFPNYVLTGSVHEGHINDTEVMTISAADMDMGIDGEVSYTI 1124 Score = 172 bits (419), Expect = 1e-40 Identities = 120/373 (32%), Positives = 180/373 (48%), Gaps = 19/373 (5%) Query: 373 VELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLD 430 VE+ ED P G V+T+ A D D + +L Y I+ GN + F + + G + V PLD Sbjct: 778 VEVPEDAPVGGTVLTVNANDLDHGFNGKLLYAISDGNDKSHFQMDFETGE--LKVLMPLD 835 Query: 431 FKQERRYVLTVSATDSGGRSDT--AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 + + Y +TV +D G T + + I +TD N+ AP F+ Y ++ EDA +G + Sbjct: 836 RETQSTYDVTVKISDMGKPQHTRKSPLTITLTDVNDNAPQFDLKQYDVAIPEDAEVGLSF 895 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 L V A+D D G N ++ YS+ S+ F I+ TG ++ LDRET + Sbjct: 896 LAVHASDRDEGRNQEVRYSIISD---------SPSFDIDIITGELSVAGPLDRETNPVHE 946 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 + V A D LS + V +S+ D+NDN P Y I ED G +V V A D Sbjct: 947 IRVQATDLSDSPLSSSVIVRVSLDDINDNPPRCLLPEYKVKIREDLPTGAAVLSVQAHDP 1006 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 D NG + Y LD F ID G +R + LD E +++ D G P S Sbjct: 1007 DNPPNGTVRYRLDTSG--SSKFSIDTDYGTLRLVEMLDYEVTQLYEIVVAIRDEGIPAMS 1064 Query: 669 STVIVHIKIEDINDS--PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 ST + +++ D+N++ PVF + LT + E T + I A D D G + V Y+I Sbjct: 1065 STCRIVVEVVDVNENTHAPVFPNYVLTGSVHEGHINDTEVMTISAADMDMGIDGEVSYTI 1124 Query: 727 KGGDDSNSFSLET 739 + G FS+++ Sbjct: 1125 RDGSGLGRFSIDS 1137 Score = 161 bits (390), Expect = 3e-37 Identities = 144/535 (26%), Positives = 240/535 (44%), Gaps = 37/535 (6%) Query: 223 YRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAY 282 Y I G ++T ++ I ++DVN+ P F + ++SE+ P+ +I++V+A+ Sbjct: 160 YLTAIAQSSSGGVRSTSTAEVHIVVQDVNEQPPLFLRGNYAATISEDYPVFSNIIQVEAH 219 Query: 283 DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG 342 D+D G N E+ Y+ + D I +G V + LD + Q+ Y L V A D G Sbjct: 220 DSDSGTNGEVYYS-----FRQQTD-QFAIHTTTGVVSLTRPLDFDQQSSYTLTVVAKDRG 273 Query: 343 DPPRSATATXXXXXXXXXXXXXXFMPGQYEVE----LAEDEPPGTPVVTLTATDAD---E 395 P + +E ++ + GT + TD D Sbjct: 274 FTPYGGLPLTSPVQLRIYVQQVNKHSPEIRIEKQPTVSRNSEIGTVFAVVGVTDEDGGVN 333 Query: 396 DNRLHYEITGGNTRGRFSI--TSQNGRGLITVAQP-LDFKQERRYVLTVSATDSG--GRS 450 +I G+ G F + + GR + +A+ L + +TV+A+D G +S Sbjct: 334 GEIAALDIIDGDPGGFFRVQPSPSPGRYQLQIARSLLSSSLPHAFNVTVAASDRGLSPKS 393 Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510 + +V + + A NY F N + ++ E P+ T L V A S VG N +Y Sbjct: 394 TSLVVGVVLDGAMNYEAYFTNDFFNTTINELMPVNTPFLSV-APRSAVG-NTGFSY---- 447 Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570 + F I TG ++ LDRET Y TV R+ +++DT V + Sbjct: 448 -----VITDSSLPFSIGTHTGMLSVAFDLDRETTPEYEFTVAVRNAKQQTIADTR-VVVI 501 Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630 + D NDN P F++++YT + E+ + V V A+D D+G NG I Y + + F Sbjct: 502 LSDANDNNPSFEEEIYTVEVEENRPAHSQVLVVRASDPDLGENGFISYSI--ANLNAVPF 559 Query: 631 VIDPASGVIRTNKALDRESVA-THDLKAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFE 688 ID +G I T+K LD E++ + L+ A D G+P + + +V + + ++ND+ P FE Sbjct: 560 TIDHETGSINTSKVLDYETMRHQYRLRVRASDWGSPFRREAKAVVIVNLINLNDNRPKFE 619 Query: 689 SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 I+++ P G I I A D DE Y I G+ ++ FS+ + G+ Sbjct: 620 KINCVGAIAKSFPSGRAIALISALDFDENR---PRYWITSGNVNDLFSINPQSGN 671 Score = 151 bits (365), Expect = 4e-34 Identities = 147/571 (25%), Positives = 242/571 (42%), Gaps = 32/571 (5%) Query: 323 QLDRETQAKYQLLVTATDGGDPPRS-ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381 +++RE + +Y L A RS +TA F+ G Y ++ED P Sbjct: 150 KVNREVRPEYYLTAIAQSSSGGVRSTSTAEVHIVVQDVNEQPPLFLRGNYAATISEDYPV 209 Query: 382 GTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441 + ++ + A D+D + +F+I + G ++++ +PLDF Q+ Y LTV Sbjct: 210 FSNIIQVEAHDSDSGTNGEVYYSFRQQTDQFAIHTTTG--VVSLTRPLDFDQQSSYTLTV 267 Query: 442 SATDSG-----GRSDTAMVQINI--TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494 A D G G T+ VQ+ I N ++P +V ++ IGT VV T Sbjct: 268 VAKDRGFTPYGGLPLTSPVQLRIYVQQVNKHSPEIR-IEKQPTVSRNSEIGTVFAVVGVT 326 Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT-TNKLLDRETMSGYLLTVTA 553 D D G+N +I + I + Q +P + LL + +TV A Sbjct: 327 DEDGGVNGEI--AALDIIDGDPGGFFRVQPSPSPGRYQLQIARSLLSSSLPHAFNVTVAA 384 Query: 554 RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613 D G+ S + V + + + E F + I E V T V A VG Sbjct: 385 SDRGLSPKSTSLVVGVVLDGAMNYEAYFTNDFFNTTINELMPVNTPFLSVAPRSA-VGNT 443 Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673 G + D F I +G++ LDRE+ ++ VA+ + V Sbjct: 444 GFSYVITD----SSLPFSIGTHTGMLSVAFDLDRETTPEYEF-TVAVRNAKQQTIADTRV 498 Query: 674 HIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN 733 + + D ND+ P FE + T + EN P + + +RA DPD G N + YSI ++ Sbjct: 499 VVILSDANDNNPSFEEEIYTVEVEENRPAHSQVLVVRASDPDLGENGFISYSI-ANLNAV 557 Query: 734 SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAAS--PPLWNDVRVEILVT--DVND 789 F+++ GS V LDYE+ R +Y L +RA+ P + + ++V ++ND Sbjct: 558 PFTIDHETGSINTSKV----LDYETMRHQYRLRVRASDWGSPFRREAKAVVIVNLINLND 613 Query: 790 NAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGS 848 N P + + K FP G + A D D ++ +Y I SGN +L +N +G+ Sbjct: 614 NRPKFEKINCVGAIAKS-FPSGRAIALISALDFD-ENRPRYWITSGNVNDLFSINPQSGN 671 Query: 849 MTLSPQLNTNVPKLATMEVSVTDGVNEIKAM 879 +TLS + + P ++ + DG + M Sbjct: 672 LTLSRPVADSDPLFYSLRIEARDGPTSVSYM 702 Score = 134 bits (323), Expect = 4e-29 Identities = 91/299 (30%), Positives = 153/299 (51%), Gaps = 29/299 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D ND++P F+++QY+ ++ E A G + L + A+D+D G+N EV Y+I +D+ Sbjct: 864 ITLTDVNDNAPQFDLKQYDVAIPEDAEVGLSFLAVHASDRDEGRNQEVRYSI---ISDSP 920 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + F ID +G L LDRE + + V+ATD + L Sbjct: 921 S------------------FDIDIITGELSVAGPLDRETNPVHEIRVQATDLSD---SPL 959 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SS+ + V++ D NDN P+ Y V + ED+ + ++A D D N +RY Sbjct: 960 SSSVIVRVSLDDINDNPPRCLLPEYKVKIREDLPT--GAAVLSVQAHDPDNPPNGTVRYR 1017 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 + + +FSID+ G + LV+ LDYE + Y +V+ +D G P+ S+T ++++ + DV Sbjct: 1018 LDTSGSS-KFSIDTDYGTLRLVEMLDYEVTQLYEIVVAIRDEGIPAMSSTCRIVVEVVDV 1076 Query: 251 NDN--APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 N+N AP F + SV E ++ + A D D G++ E++YT+ D G + Sbjct: 1077 NENTHAPVFPNYVLTGSVHEGHINDTEVMTISAADMDMGIDGEVSYTIRDGSGLGRFSI 1135 Score = 93.5 bits (222), Expect = 8e-17 Identities = 88/302 (29%), Positives = 142/302 (47%), Gaps = 31/302 (10%) Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGI-----NAQITYSLS-SEISNEAVAHH-- 520 F + Y A++ E++PI T + +T+ +G+ +A + Y+L S++S+ A Sbjct: 71 FTRSIYNATIAENSPIRTFI----STEQKMGVYLPDPSATVRYTLQESDVSDLFSARPEV 126 Query: 521 --DQQFV---INP-QTGAITTNKLLDRETMSGYLLTVTARD--GGVPSLSDTTDVEISVV 572 D F+ P + + N ++RE Y LT A+ GGV S S T +V I V Sbjct: 127 VGDFAFLRIRTRPCRNKSQCPNLKVNREVRPEYYLTAIAQSSSGGVRSTS-TAEVHIVVQ 185 Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632 DVN+ P+F + Y A I ED V +++ QV A D+D G NG ++Y ++ F I Sbjct: 186 DVNEQPPLFLRGNYAATISEDYPVFSNIIQVEAHDSDSGTNGEVYYSF---RQQTDQFAI 242 Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGG-TP----PQSSTVIVHIKIEDINDSPPVF 687 +GV+ + LD + +++ L VA D G TP P +S V + I ++ +N P Sbjct: 243 HTTTGVVSLTRPLDFDQQSSYTLTVVAKDRGFTPYGGLPLTSPVQLRIYVQQVNKHSPEI 302 Query: 688 ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA-VVHYSIKGGDDSNSFSLETRQGSDKA 746 + +S NS IGT + D D G N + I GD F ++ + Sbjct: 303 RIEKQP-TVSRNSEIGTVFAVVGVTDEDGGVNGEIAALDIIDGDPGGFFRVQPSPSPGRY 361 Query: 747 EL 748 +L Sbjct: 362 QL 363 Score = 81.0 bits (191), Expect = 4e-13 Identities = 71/234 (30%), Positives = 110/234 (47%), Gaps = 29/234 (12%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 D ND++P FE + Y V E + + VL ++A+D D+G+N + Y+I + A Sbjct: 504 DANDNNPSFEEEIYTVEVEENRPAHSQVLVVRASDPDLGENGFISYSIANLNAVP----- 558 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA-RYTVLVKATDQASPVSDRLSST 133 F ID +G++ T LD E + +Y + V+A+D SP R + Sbjct: 559 ---------------FTIDHETGSINTSKVLDYETMRHQYRLRVRASDWGSPF--RREAK 601 Query: 134 ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG 193 A + VN+I+ NDN P+F + ++ + S IA I A D D + RY I Sbjct: 602 AVVIVNLINLNDNRPKFEKINCVGAIAK--SFPSGRAIALISALDFD---ENRPRYWITS 656 Query: 194 GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG-GSPSRSNTTQLLIN 246 GN FSI+ SG+++L + + Y L I A+DG S S T + N Sbjct: 657 GNVNDLFSINPQSGNLTLSRPVADSDPLFYSLRIEARDGPTSVSYMRTNMTITN 710 Score = 68.9 bits (161), Expect = 2e-09 Identities = 50/163 (30%), Positives = 82/163 (50%), Gaps = 16/163 (9%) Query: 642 NKALDRESVATHDLKAVA-IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS 700 N ++RE + L A+A G +ST VHI ++D+N+ PP+F ISE+ Sbjct: 148 NLKVNREVRPEYYLTAIAQSSSGGVRSTSTAEVHIVVQDVNEQPPLFLRGNYAATISEDY 207 Query: 701 PIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPR 760 P+ + I ++ AHD D G N V+YS + ++ F++ T G L +D D +S Sbjct: 208 PVFSNIIQVEAHDSDSGTNGEVYYSFR--QQTDQFAIHTTTG--VVSLTRPLDFDQQS-- 261 Query: 761 KKYELVI----RAASP----PLWNDVRVEILVTDVNDNAPVMK 795 Y L + R +P PL + V++ I V VN ++P ++ Sbjct: 262 -SYTLTVVAKDRGFTPYGGLPLTSPVQLRIYVQQVNKHSPEIR 303 Score = 66.1 bits (154), Expect = 1e-08 Identities = 59/197 (29%), Positives = 87/197 (44%), Gaps = 27/197 (13%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++++ D ND+ P + +Y+ +RE +G VL+++A D D N V Y + DT Sbjct: 966 RVSLDDINDNPPRCLLPEYKVKIREDLPTGAAVLSVQAHDPDNPPNGTVRYRL-----DT 1020 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 F ID G L LD E Y ++V D+ P Sbjct: 1021 SGSSK---------------FSIDTDYGTLRLVEMLDYEVTQLYEIVVAIRDEGIPA--- 1062 Query: 130 LSSTATIHVNIIDDNDNY--PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 +SST I V ++D N+N P F T SV E + D V+ I A D D+G + + Sbjct: 1063 MSSTCRIVVEVVDVNENTHAPVFPNYVLTGSVHEG-HINDTEVMT-ISAADMDMGIDGEV 1120 Query: 188 RYAIIGGNTQMQFSIDS 204 Y I G+ +FSIDS Sbjct: 1121 SYTIRDGSGLGRFSIDS 1137 >UniRef50_Q4S490 Cluster: Chromosome 1 SCAF14742, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 1 SCAF14742, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 1105 Score = 182 bits (442), Expect = 2e-43 Identities = 164/625 (26%), Positives = 275/625 (44%), Gaps = 68/625 (10%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F + R G L T+ LDRE++ R + L + + + V ++D ND+ P+ Sbjct: 46 FSVSARDGVLSTQGRLDREELCRGSDLCEVLLSVLYRRSGAMTCLRVRVEVMDQNDHSPR 105 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209 F ++D+ +++ G I + G S ++ Sbjct: 106 FPR------AEQDLEISEM------------AGLRMRIPFGASG----------SKQAEL 137 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSEN 269 ++K LD E S L++ A D G P RS +T + + I D NDN+P F S + E+ Sbjct: 138 VIIKELDREVQESVELILVAWDKGDPPRSGSTSIHVRILDSNDNSPTFEDSSPTLELPED 197 Query: 270 VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQ 329 G +++R++A D D+G+N E+ Y+++ + V + +DP++ V LD E Q Sbjct: 198 TARGTTVIRLKATDPDQGLNGEVAYSLS-RHTRPEVQRLLAVDPQTAAVSLKAPLDYEVQ 256 Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM-----PGQYEVELAEDEPPGTP 384 + Y+++V A D G A + PG + E P T Sbjct: 257 SSYEVVVEARDRGPNAVPAYCKLHIKLLDVNDNAPRILFIWDRPGSPGPTVLEGAPRDTF 316 Query: 385 VVTLTATDAD--EDNRLHYEITGGNTRGRFSITS-QNGRGLITVAQPLDFKQERRYVLTV 441 + + DAD + ++ EI G+ G F + Q+G I LD ++ Y +T+ Sbjct: 317 LSLVMVLDADSGRNGQVKAEILDGS--GPFRLKHVQDGSYTIVTNGTLDREKVTHYNITL 374 Query: 442 SATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499 A D G S + +++ D N+ APVF + Y AS E G VL V A D D+ Sbjct: 375 LARDHGDPPLSTLGQLTVHVLDENDNAPVFSTSLYKASFEETNSTGYQVLKVQARDVDLE 434 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 ++ +++Y + + +A + F ++P +G + + LD ET Y V A D G P Sbjct: 435 LSGRVSYFIRNATRAQAATY----FSVHPTSGLVRALRPLDYETSRSYWFLVEAVDQGHP 490 Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQ-----LYTANIMEDALVGTSVSQVG---------- 604 LS T V+I + DVNDN PV K+ + + +I +A G V+++G Sbjct: 491 PLSSTATVQIEIRDVNDNYPVVKEPAPRRGVASLSIPVNADKGEIVTELGMSTREGRAAF 550 Query: 605 ------ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA-THDLKA 657 A DAD GLNG++ Y+L + F +D A+G + N + + T L Sbjct: 551 LVSTIQAEDADSGLNGQLTYQL-TRAEPNPLFWLDAATGQLFVNTTNATQLIGQTFRLDI 609 Query: 658 VAIDGGTPPQSSTVIVHIKIEDIND 682 DGG P S+ + + + ++ D Sbjct: 610 SVSDGGRPSLSTGLTLEVTFINLRD 634 Score = 176 bits (428), Expect = 8e-42 Identities = 124/401 (30%), Positives = 193/401 (48%), Gaps = 21/401 (5%) Query: 323 QLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPG 382 +LDRE Q +L++ A D GDPPRS + + F +EL ED G Sbjct: 142 ELDREVQESVELILVAWDKGDPPRSGSTSIHVRILDSNDNSPTFEDSSPTLELPEDTARG 201 Query: 383 TPVVTLTATDADE--DNRLHYEITGGNTRGRFS--ITSQNGRGLITVAQPLDFKQERRYV 438 T V+ L ATD D+ + + Y ++ +TR + +++ PLD++ + Y Sbjct: 202 TTVIRLKATDPDQGLNGEVAYSLSR-HTRPEVQRLLAVDPQTAAVSLKAPLDYEVQSSYE 260 Query: 439 LTVSATDSGGRSDTAMVQINIT--DANNYAP----VFENAPYTA-SVFEDAPIGTTVLVV 491 + V A D G + A +++I D N+ AP +++ +V E AP T + +V Sbjct: 261 VVVEARDRGPNAVPAYCKLHIKLLDVNDNAPRILFIWDRPGSPGPTVLEGAPRDTFLSLV 320 Query: 492 SATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTV 551 D+D G N Q+ + + H + + I TN LDRE ++ Y +T+ Sbjct: 321 MVLDADSGRNGQVKAEILDGSGPFRLKH------VQDGSYTIVTNGTLDREKVTHYNITL 374 Query: 552 TARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG 611 ARD G P LS + + V+D NDN PVF LY A+ E G V +V A D D+ Sbjct: 375 LARDHGDPPLSTLGQLTVHVLDENDNAPVFSTSLYKASFEETNSTGYQVLKVQARDVDLE 434 Query: 612 LNGRIHYELDPKDREEGS--FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSS 669 L+GR+ Y + R + + F + P SG++R + LD E+ ++ A+D G PP SS Sbjct: 435 LSGRVSYFIRNATRAQAATYFSVHPTSGLVRALRPLDYETSRSYWFLVEAVDQGHPPLSS 494 Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENS-PIGTTIGEI 709 T V I+I D+ND+ PV + ++ S P+ GEI Sbjct: 495 TATVQIEIRDVNDNYPVVKEPAPRRGVASLSIPVNADKGEI 535 Score = 167 bits (405), Expect = 5e-39 Identities = 130/417 (31%), Positives = 203/417 (48%), Gaps = 24/417 (5%) Query: 393 ADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RS 450 A++D + E+ G R F + L+ + + LD + + L + A D G RS Sbjct: 109 AEQDLEIS-EMAGLRMRIPFGASGSKQAELVIIKE-LDREVQESVELILVAWDKGDPPRS 166 Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510 + + + I D+N+ +P FE++ T + ED GTTV+ + ATD D G+N ++ YSLS Sbjct: 167 GSTSIHVRILDSNDNSPTFEDSSPTLELPEDTARGTTVIRLKATDPDQGLNGEVAYSLSR 226 Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEIS 570 E + ++PQT A++ LD E S Y + V ARD G ++ + I Sbjct: 227 HTRPEV----QRLLAVDPQTAAVSLKAPLDYEVQSSYEVVVEARDRGPNAVPAYCKLHIK 282 Query: 571 VVDVNDNEP--VF---KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE-LDPKD 624 ++DVNDN P +F + ++E A T +S V DAD G NG++ E LD Sbjct: 283 LLDVNDNAPRILFIWDRPGSPGPTVLEGAPRDTFLSLVMVLDADSGRNGQVKAEILDGSG 342 Query: 625 REEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP 684 V D S I TN LDRE V +++ +A D G PP S+ + + + D ND+ Sbjct: 343 PFRLKHVQD-GSYTIVTNGTLDREKVTHYNITLLARDHGDPPLSTLGQLTVHVLDENDNA 401 Query: 685 PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNS---FSLETRQ 741 PVF + E + G + +++A D D + V Y I+ + + FS+ Sbjct: 402 PVFSTSLYKASFEETNSTGYQVLKVQARDVDLELSGRVSYFIRNATRAQAATYFSVHPTS 461 Query: 742 GSDKAELVTMVDLDYESPRKKYELV--IRAASPPLWNDVRVEILVTDVNDNAPVMKD 796 G +A + LDYE+ R + LV + PPL + V+I + DVNDN PV+K+ Sbjct: 462 GLVRA----LRPLDYETSRSYWFLVEAVDQGHPPLSSTATVQIEIRDVNDNYPVVKE 514 Score = 166 bits (404), Expect = 7e-39 Identities = 151/520 (29%), Positives = 224/520 (43%), Gaps = 54/520 (10%) Query: 95 RSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKT 154 + L+ LDRE +++ A D+ P S + +IHV I+D NDN P F + + Sbjct: 133 KQAELVIIKELDREVQESVELILVAWDKGDPPR---SGSTSIHVRILDSNDNSPTFEDSS 189 Query: 155 YTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI---IGGNTQMQFSIDSLSGDVSL 211 T+ + ED + + ++KATD D G N + Y++ Q ++D + VSL Sbjct: 190 PTLELPEDTA--RGTTVIRLKATDPDQGLNGEVAYSLSRHTRPEVQRLLAVDPQTAAVSL 247 Query: 212 VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE-----SV 266 LDYE SY +V+ A+D G + +L I + DVNDNAPR + +V Sbjct: 248 KAPLDYEVQSSYEVVVEARDRGPNAVPAYCKLHIKLLDVNDNAPRILFIWDRPGSPGPTV 307 Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326 E P + V DAD G N ++ + D +G L D S + T+G LDR Sbjct: 308 LEGAPRDTFLSLVMVLDADSGRNGQVKAEILDG--SGPFRLKHVQDG-SYTIVTNGTLDR 364 Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386 E Y + + A D GDPP S F Y+ E G V+ Sbjct: 365 EKVTHYNITLLARDHGDPPLSTLGQLTVHVLDENDNAPVFSTSLYKASFEETNSTGYQVL 424 Query: 387 TLTATDADED--NRLHYEI---TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTV 441 + A D D + R+ Y I T FS+ + GL+ +PLD++ R Y V Sbjct: 425 KVQARDVDLELSGRVSYFIRNATRAQAATYFSVHPTS--GLVRALRPLDYETSRSYWFLV 482 Query: 442 SATDSG--GRSDTAMVQINITDAN-NYAPVFENAPYTASVFEDAPI-------------- 484 A D G S TA VQI I D N NY V E AP P+ Sbjct: 483 EAVDQGHPPLSSTATVQIEIRDVNDNYPVVKEPAPRRGVASLSIPVNADKGEIVTELGMS 542 Query: 485 ---GTTVLVVS---ATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL 538 G +VS A D+D G+N Q+TY L+ A + F ++ TG + N Sbjct: 543 TREGRAAFLVSTIQAEDADSGLNGQLTYQLTR-------AEPNPLFWLDAATGQLFVNTT 595 Query: 539 LDRETM-SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577 + + + L ++ DGG PSLS +E++ +++ D+ Sbjct: 596 NATQLIGQTFRLDISVSDGGRPSLSTGLTLEVTFINLRDH 635 Score = 158 bits (383), Expect = 2e-36 Identities = 107/345 (31%), Positives = 168/345 (48%), Gaps = 24/345 (6%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + +LD ND+SP FE + E + GTTV+ LKATD D G N EV Y++ T Sbjct: 173 VRILDSNDNSPTFEDSSPTLELPEDTARGTTVIRLKATDPDQGLNGEVAYSLSRHT---- 228 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 PE VQ + +D ++ A+ +A LD E + Y V+V+A D+ + + Sbjct: 229 RPE------------VQRLLAVDPQTAAVSLKAPLDYEVQSSYEVVVEARDRGP---NAV 273 Query: 131 SSTATIHVNIIDDNDNYPQFS---EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 + +H+ ++D NDN P+ ++ + + ++ + DAD G N + Sbjct: 274 PAYCKLHIKLLDVNDNAPRILFIWDRPGSPGPTVLEGAPRDTFLSLVMVLDADSGRNGQV 333 Query: 188 RYAIIGGNTQMQFS-IDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 + I+ G+ + + S + TLD E+V Y + + A+D G P S QL ++ Sbjct: 334 KAEILDGSGPFRLKHVQDGSYTIVTNGTLDREKVTHYNITLLARDHGDPPLSTLGQLTVH 393 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + D NDNAP F TSL++ S E GY +++VQA D D ++ ++Y + + Sbjct: 394 VLDENDNAPVFSTSLYKASFEETNSTGYQVLKVQARDVDLELSGRVSYFIRNAT-RAQAA 452 Query: 307 LPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 ++ P SG V LD ET Y LV A D G PP S+TAT Sbjct: 453 TYFSVHPTSGLVRALRPLDYETSRSYWFLVEAVDQGHPPLSSTAT 497 Score = 109 bits (263), Expect = 8e-22 Identities = 111/381 (29%), Positives = 173/381 (45%), Gaps = 59/381 (15%) Query: 2 SVPFCIHQQINVLDCNDHSP--VFEMQQYEA---SVREGASSGTTVLTLKATDQDIGKNA 56 +VP I +LD ND++P +F + + +V EGA T + + D D G+N Sbjct: 272 AVPAYCKLHIKLLDVNDNAPRILFIWDRPGSPGPTVLEGAPRDTFLSLVMVLDADSGRNG 331 Query: 57 EVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVL 116 +V+ I D P VQD S ++T +LDREKV Y + Sbjct: 332 QVKAEI----LDGSGP--------FRLKHVQD------GSYTIVTNGTLDREKVTHYNIT 373 Query: 117 VKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKA 176 + A D P LS+ + V+++D+NDN P FS Y S +E S T V+ K++A Sbjct: 374 LLARDHGDPP---LSTLGQLTVHVLDENDNAPVFSTSLYKASFEETNS-TGYQVL-KVQA 428 Query: 177 TDADVGANSAIRYAIIGGNTQMQ----FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232 D D+ + + Y I T+ Q FS+ SG V ++ LDYE RSY ++ A D Sbjct: 429 RDVDLELSGRVSY-FIRNATRAQAATYFSVHPTSGLVRALRPLDYETSRSYWFLVEAVDQ 487 Query: 233 GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV-SENVPI------------------- 272 G P S+T + I IRDVNDN P + V S ++P+ Sbjct: 488 GHPPLSSTATVQIEIRDVNDNYPVVKEPAPRRGVASLSIPVNADKGEIVTELGMSTREGR 547 Query: 273 -GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK 331 + + +QA DAD G+N +LTY +T + +D +G ++ + + + Sbjct: 548 AAFLVSTIQAEDADSGLNGQLTYQLT----RAEPNPLFWLDAATGQLFVNTTNATQLIGQ 603 Query: 332 -YQLLVTATDGGDPPRSATAT 351 ++L ++ +DGG P S T Sbjct: 604 TFRLDISVSDGGRPSLSTGLT 624 >UniRef50_UPI00006A195F Cluster: Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin).; n=4; Xenopus tropicalis|Rep: Cadherin-16 precursor (Kidney-specific cadherin) (Ksp-cadherin). - Xenopus tropicalis Length = 804 Score = 181 bits (441), Expect = 2e-43 Identities = 201/719 (27%), Positives = 310/719 (43%), Gaps = 62/719 (8%) Query: 87 QDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDN 146 +++F +D SG L DRE+ A YT+ V V + LS TIH+ + D+NDN Sbjct: 59 EEIFGVDPESGFLYALKPFDRERKASYTLQVTLR---KGVEEILSQMVTIHIMVKDENDN 115 Query: 147 YPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA--NSAIRYAII----GGNTQMQF 200 P F+E T+ V + + ATD D + N+ +RY +I + + F Sbjct: 116 MPVFTENTFYGIVSK--GTKQGVAFMHVNATDLDDSSTPNADLRYKLISRYPARSYENMF 173 Query: 201 SIDSLSGDVSL----VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256 +D +G +SL V +L +V+ ++L ++ +D G T+ + I + Sbjct: 174 QVDPKTGSISLTEQGVSSLSKLEVKYFKLEVQVKDFGDEPMGYTSVANLEISVAENTWIA 233 Query: 257 FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316 L QE+ P S V+ + EL Y++ D++ V ID G Sbjct: 234 ESPVLLQENQKGGYPRIISEVKWN--------STELHYSLKG-DFSEEV---FRID-EDG 280 Query: 317 WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376 +Y +LDRETQA+YQ+ V+A + D P + F Y VE+ Sbjct: 281 KIYIMSELDRETQAEYQIEVSAMNDEDIPYADHLLIVIKVIDENDNTPTFPQDTYHVEVT 340 Query: 377 EDEPPGTPVVTLTATDADEDN----RLHYEITGGNTR--GRFSITSQNGRGLITVAQ-PL 429 E GT +V LTATDAD+ N ++ Y+IT + F + G +T+ L Sbjct: 341 ERTTKGTLLVHLTATDADDRNTKNAQIRYKITSQEPKLPKDFLFHLEEHTGHLTLQDAKL 400 Query: 430 DFKQERRYVLTVSATDSG----GRSDTAMVQINITDANNYAPVFENAPYTASVF-EDAPI 484 ++Y L +SATD G G S T V IN+ D N+ PVF + + EDA Sbjct: 401 KASIAKKYKLEISATDLGGDPEGLSSTCFVFINVIDVNDSPPVFVKNKFAPFLIPEDAQT 460 Query: 485 GTTVLVVSATDSDVGI-NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 G ++ ++ATD D I N I + + S + Q T I K LD E Sbjct: 461 GMLIITLTATDEDEQIENKIIDFYIQSGNEDGTFGITTNQ---EQSTMTIFLEKDLDYEQ 517 Query: 544 MSGYLLTVTARD-----GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 Y L +T R+ G S + T + I VV+VN+ PVF Q+ Y + E A G+ Sbjct: 518 TQEYNLIITVRNRAELLGTEYSPTSTAAIHIMVVNVNE-APVFTQKKYEVRVPESAQAGS 576 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA-THDLKA 657 + V A+D ++ + Y + ++ + I SG I+ +LDRE T+ ++ Sbjct: 577 VILAVEASDP---VSSFLSYSI--RNDSKRCLSIQEHSGKIQLLHSLDREVFEDTYTVQV 631 Query: 658 VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEG 717 + + G S+T V I I D+ND+ P+ D Y I IRA D D Sbjct: 632 LVQEKGDRGLSATADVVIYILDVNDNIPILVGDYSEEYFCTPRRDNQRI-IIRAFDLDSV 690 Query: 718 PN-AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI--RAASPP 773 N A +++ S T A L + + Y PR Y L+I + +PP Sbjct: 691 ENSAPFTFTLSNEPTLQSRWRVTALNGTHAYL--SMGISYLEPRVHYVLIIITDSGTPP 747 Score = 173 bits (420), Expect = 8e-41 Identities = 171/628 (27%), Positives = 275/628 (43%), Gaps = 45/628 (7%) Query: 192 IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251 + GN + F +D SG + +K D E+ SY L + + G S + I ++D N Sbjct: 54 LAGNDEEIFGVDPESGFLYALKPFDRERKASYTLQVTLRKGVEEILSQMVTIHIMVKDEN 113 Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG--VNAELTYTMTDKDYTGNVDLPI 309 DN P F + F VS+ G + + V A D D+ NA+L Y + + + + Sbjct: 114 DNMPVFTENTFYGIVSKGTKQGVAFMHVNATDLDDSSTPNADLRYKLISRYPARSYENMF 173 Query: 310 TIDPRSGWVYTSGQ----LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 +DP++G + + Q L + ++L V D GD P T+ Sbjct: 174 QVDPKTGSISLTEQGVSSLSKLEVKYFKLEVQVKDFGDEPMGYTSVANLEISVAENTWIA 233 Query: 366 FMPGQYEVELAEDEPPGTP-VVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLIT 424 P V L E++ G P +++ ++ E LHY + G + F I G I Sbjct: 234 ESP----VLLQENQKGGYPRIISEVKWNSTE---LHYSLKGDFSEEVFRIDED---GKIY 283 Query: 425 VAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 + LD + + Y + VSA + +D ++ I + D N+ P F Y V E Sbjct: 284 IMSELDRETQAEYQIEVSAMNDEDIPYADHLLIVIKVIDENDNTPTFPQDTYHVEVTERT 343 Query: 483 PIGTTVLVVSATDSD--VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAIT-TNKLL 539 GT ++ ++ATD+D NAQI Y ++S+ E D F + TG +T + L Sbjct: 344 TKGTLLVHLTATDADDRNTKNAQIRYKITSQ---EPKLPKDFLFHLEEHTGHLTLQDAKL 400 Query: 540 DRETMSGYLLTVTARD-GGVP-SLSDTTDVEISVVDVNDNEPVF-KQQLYTANIMEDALV 596 Y L ++A D GG P LS T V I+V+DVND+ PVF K + I EDA Sbjct: 401 KASIAKKYKLEISATDLGGDPEGLSSTCFVFINVIDVNDSPPVFVKNKFAPFLIPEDAQT 460 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI----DPASGVIRTNKALDRESVAT 652 G + + ATD D + +I E+G+F I + ++ I K LD E Sbjct: 461 GMLIITLTATDEDEQIENKIIDFYIQSGNEDGTFGITTNQEQSTMTIFLEKDLDYEQTQE 520 Query: 653 HDL-----KAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIG 707 ++L + G +ST +HI + ++N++ PVF + E++ G+ I Sbjct: 521 YNLIITVRNRAELLGTEYSPTSTAAIHIMVVNVNEA-PVFTQKKYEVRVPESAQAGSVIL 579 Query: 708 EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD-YESPRKKYELV 766 + A DP ++ + YSI+ D S++ G K +L+ +D + +E LV Sbjct: 580 AVEASDP---VSSFLSYSIR-NDSKRCLSIQEHSG--KIQLLHSLDREVFEDTYTVQVLV 633 Query: 767 IRAASPPLWNDVRVEILVTDVNDNAPVM 794 L V I + DVNDN P++ Sbjct: 634 QEKGDRGLSATADVVIYILDVNDNIPIL 661 Score = 130 bits (313), Expect = 7e-28 Identities = 164/645 (25%), Positives = 277/645 (42%), Gaps = 57/645 (8%) Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 + GN + +DP SG++Y DRE +A Y L VT G + S T Sbjct: 53 ELAGNDEEIFGVDPESGFLYALKPFDRERKASYTLQVTLRKGVEEILSQMVTIHIMVKDE 112 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR----LHYEI----TGGNTRGR 411 F + +++ G + + ATD D+ + L Y++ + Sbjct: 113 NDNMPVFTENTFYGIVSKGTKQGVAFMHVNATDLDDSSTPNADLRYKLISRYPARSYENM 172 Query: 412 FSITSQNGRGLITV--AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVF 469 F + + G +T L + + + L V D G D M ++ AN V Sbjct: 173 FQVDPKTGSISLTEQGVSSLSKLEVKYFKLEVQVKDFG---DEPMGYTSV--ANLEISVA 227 Query: 470 ENAPYTAS--VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVIN 527 EN S + ++ G ++S + + ++ YSL + S E F I+ Sbjct: 228 ENTWIAESPVLLQENQKGGYPRIISEVKWN---STELHYSLKGDFSEEV-------FRID 277 Query: 528 PQTGAITTNKLLDRETMSGYLLTVTA-RDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586 + G I LDRET + Y + V+A D +P +D + I V+D NDN P F Q Y Sbjct: 278 -EDGKIYIMSELDRETQAEYQIEVSAMNDEDIP-YADHLLIVIKVIDENDNTPTFPQDTY 335 Query: 587 TANIMEDALVGTSVSQVGATDAD--VGLNGRIHYEL---DPKDREEGSFVIDPASGVIRT 641 + E GT + + ATDAD N +I Y++ +PK ++ F ++ +G + Sbjct: 336 HVEVTERTTKGTLLVHLTATDADDRNTKNAQIRYKITSQEPKLPKDFLFHLEEHTGHLTL 395 Query: 642 NKALDRESVA-THDLKAVAIDGGTPPQ--SSTVIVHIKIEDINDSPPVF-ESDCLTFYIS 697 A + S+A + L+ A D G P+ SST V I + D+NDSPPVF ++ F I Sbjct: 396 QDAKLKASIAKKYKLEISATDLGGDPEGLSSTCFVFINVIDVNDSPPVFVKNKFAPFLIP 455 Query: 698 ENSPIGTTIGEIRAHDPDEG-PNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756 E++ G I + A D DE N ++ + I+ G++ +F + T Q + DLDY Sbjct: 456 EDAQTGMLIITLTATDEDEQIENKIIDFYIQSGNEDGTFGITTNQEQSTMTIFLEKDLDY 515 Query: 757 ESPRKKYELVI--RAASPPLWND------VRVEILVTDVNDNAPVMKDFQIIFNNYKDCF 808 E ++Y L+I R + L + + I+V +VN+ APV + + Sbjct: 516 EQ-TQEYNLIITVRNRAELLGTEYSPTSTAAIHIMVVNVNE-APVFTQKKYEVRVPESAQ 573 Query: 809 PVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNV-PKLATMEV 867 V A D V+ L Y I ++ + + E +G + L L+ V T++V Sbjct: 574 AGSVILAVEASD-PVSSFLSYSI-RNDSKRCLSIQEHSGKIQLLHSLDREVFEDTYTVQV 631 Query: 868 SVTD-GVNEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSP 911 V + G + A + + ++ + ++I + + D + E F +P Sbjct: 632 LVQEKGDRGLSATADVVIYILD---VNDNIPILVGDYSEEYFCTP 673 Score = 104 bits (250), Expect = 3e-20 Identities = 122/466 (26%), Positives = 203/466 (43%), Gaps = 50/466 (10%) Query: 3 VPFCIHQQI--NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD--IGKNAEV 58 +P+ H I V+D ND++P F Y V E + GT ++ L ATD D KNA++ Sbjct: 308 IPYADHLLIVIKVIDENDNTPTFPQDTYHVEVTERTTKGTLLVHLTATDADDRNTKNAQI 367 Query: 59 EYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLV 117 Y ++ + + P+D +F ++ +G L L A L +Y + + Sbjct: 368 RY--KITSQEPKLPKDF-------------LFHLEEHTGHLTLQDAKLKASIAKKYKLEI 412 Query: 118 KATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT-VSVDEDISVTDNPVIAKIKA 176 ATD + LSST + +N+ID ND+ P F + + + ED +I + A Sbjct: 413 SATDLGGD-PEGLSSTCFVFINVIDVNDSPPVFVKNKFAPFLIPEDAQT--GMLIITLTA 469 Query: 177 TDADVG-ANSAIRYAIIGGNTQMQFSI----DSLSGDVSLVKTLDYEQVRSYRLVIRAQD 231 TD D N I + I GN F I + + + L K LDYEQ + Y L+I ++ Sbjct: 470 TDEDEQIENKIIDFYIQSGNEDGTFGITTNQEQSTMTIFLEKDLDYEQTQEYNLIITVRN 529 Query: 232 -----GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE 286 G S ++T + I + +VN+ AP F ++ V E+ G I+ V+A D Sbjct: 530 RAELLGTEYSPTSTAAIHIMVVNVNE-APVFTQKKYEVRVPESAQAGSVILAVEASDP-- 586 Query: 287 GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET-QAKYQLLVTATDGGDPP 345 V++ L+Y++ + + ++I SG + LDRE + Y + V + GD Sbjct: 587 -VSSFLSYSIRN-----DSKRCLSIQEHSGKIQLLHSLDREVFEDTYTVQVLVQEKGDRG 640 Query: 346 RSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-DNRLHYEIT 404 SATA + G Y E + + A D D +N + T Sbjct: 641 LSATA-DVVIYILDVNDNIPILVGDYSEEYFCTPRRDNQRIIIRAFDLDSVENSAPFTFT 699 Query: 405 GGN---TRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447 N + R+ +T+ NG ++ + + + R + + + TDSG Sbjct: 700 LSNEPTLQSRWRVTALNGTHAY-LSMGISYLEPRVHYVLIIITDSG 744 Score = 93.5 bits (222), Expect = 8e-17 Identities = 100/392 (25%), Positives = 170/392 (43%), Gaps = 39/392 (9%) Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 +I + + + E + ++ F ++P++G + K DRE + Y L VT R G LS Sbjct: 41 KIILATDGQYNTELAGNDEEIFGVDPESGFLYALKPFDRERKASYTLQVTLRKGVEEILS 100 Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL--NGRIHYEL 620 + I V D NDN PVF + + + + G + V ATD D N + Y+L Sbjct: 101 QMVTIHIMVKDENDNMPVFTENTFYGIVSKGTKQGVAFMHVNATDLDDSSTPNADLRYKL 160 Query: 621 ---DPKDREEGSFVIDPASGVIRTNK----ALDRESVATHDLKAVAIDGGTPPQSSTVIV 673 P E F +DP +G I + +L + V L+ D G P T + Sbjct: 161 ISRYPARSYENMFQVDPKTGSISLTEQGVSSLSKLEVKYFKLEVQVKDFGDEPMGYTSVA 220 Query: 674 HIKIEDINDSPPVFESDCLTFYISENSPIG--TTIGEIRAHDPDEGPNAVVHYSIKGGDD 731 +++I + ++ + ES L + EN G I E++ + + +HYS+KG Sbjct: 221 NLEI-SVAENTWIAESPVL---LQENQKGGYPRIISEVKWNSTE------LHYSLKG--- 267 Query: 732 SNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASP---PLWNDVRVEILVTDVN 788 FS E + + ++ M +LD E+ + +Y++ + A + P + + + I V D N Sbjct: 268 --DFSEEVFRIDEDGKIYIMSELDRET-QAEYQIEVSAMNDEDIPYADHLLIVIKVIDEN 324 Query: 789 DNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTD----KLQYRILSGN----NANLI 840 DN P + + A DAD + +++Y+I S L Sbjct: 325 DNTPTFPQDTYHVEVTERTTKGTLLVHLTATDADDRNTKNAQIRYKITSQEPKLPKDFLF 384 Query: 841 LLNETTGSMTL-SPQLNTNVPKLATMEVSVTD 871 L E TG +TL +L ++ K +E+S TD Sbjct: 385 HLEEHTGHLTLQDAKLKASIAKKYKLEISATD 416 Score = 90.6 bits (215), Expect = 5e-16 Identities = 90/345 (26%), Positives = 155/345 (44%), Gaps = 29/345 (8%) Query: 11 INVLDCNDHSPVFEMQQYEAS-VREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 INV+D ND PVF ++ + E A +G ++TL ATD+D ++E I + Sbjct: 432 INVIDVNDSPPVFVKNKFAPFLIPEDAQTGMLIITLTATDED----EQIENKIIDFYIQS 487 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 N + +F LD E+ Y +++ ++A + Sbjct: 488 GNEDGTFGITTNQEQSTMTIF----------LEKDLDYEQTQEYNLIITVRNRAELLGTE 537 Query: 130 LS--STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 S STA IH+ +++ N+ P F++K Y V V E S VI ++A+D +S + Sbjct: 538 YSPTSTAAIHIMVVNVNEA-PVFTQKKYEVRVPE--SAQAGSVILAVEASDP---VSSFL 591 Query: 188 RYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVR-SYRLVIRAQDGGSPSRSNTTQLLIN 246 Y+I +++ SI SG + L+ +LD E +Y + + Q+ G S T ++I Sbjct: 592 SYSI-RNDSKRCLSIQEHSGKIQLLHSLDREVFEDTYTVQVLVQEKGDRGLSATADVVIY 650 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN-AELTYTMTDKDYTGNV 305 I DVNDN P +E I+ ++A+D D N A T+T++++ + Sbjct: 651 ILDVNDNIPILVGDYSEEYFCTPRRDNQRII-IRAFDLDSVENSAPFTFTLSNEPTLQSR 709 Query: 306 DLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350 ++ ++ + G E + Y L++ TD G PP+S A Sbjct: 710 WRVTALNGTHAYL-SMGISYLEPRVHYVLIII-TDSGTPPQSKLA 752 >UniRef50_Q4S1I3 Cluster: Chromosome 6 SCAF14768, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 6 SCAF14768, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 697 Score = 180 bits (438), Expect = 5e-43 Identities = 135/444 (30%), Positives = 219/444 (49%), Gaps = 38/444 (8%) Query: 378 DEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436 +E P V+ +D+D ++ + Y ++G F I G I + + LD +++ Sbjct: 18 EEDPTPQVIGQLRSDSDRGESSIRYILSGEGAGDLFQIDESTGE--IWMLRKLDREEKAS 75 Query: 437 YVLTVSATDSGGRSDTAMVQ---INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 YVL A + + I + D N+ P+F+N PY +S+ E P+GTTV V+A Sbjct: 76 YVLQAQAINRRSSQPEELQSEFIITVQDINDNVPLFQNEPYESSIPEMCPLGTTVARVTA 135 Query: 494 TDSD---VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN-KLLDRETMSGYLL 549 TD+D G NA++ YS + + F + P+TG I T+ +DRE YL+ Sbjct: 136 TDADDPMFGNNAKLIYS---------ILQGEPYFSVEPKTGIIVTSWPNMDREARDQYLV 186 Query: 550 TVTARD--GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 V A+D G S +T V +S+ DVNDN P F+ +Y + E+A VGT+V ++ A D Sbjct: 187 VVQAKDMLGLSGGHSSSTTVTVSLTDVNDNGPTFQHHVYAFGVPENAAVGTTVGRIMAED 246 Query: 608 ADVGLNGRIHYELDPKDREEGSFVI--DPAS--GVIRTNKALDRESVATHDLKAVAIDGG 663 D+G+N ++ Y L+ E G+F+I DP + GV+ K LD E+ L A A++ Sbjct: 247 GDIGINAKMSYSLEDSLEESGTFIIRTDPVTQEGVVLLAKPLDFETKRRFVLAAEAVNDY 306 Query: 664 TPPQ-------SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 + + + I +ED+ D PPVF + + EN +GT +G + A D D Sbjct: 307 PDTRFLPLDKFRDRMTLKIIVEDV-DEPPVFLHPLYEWKVPENVVVGTAVGSVSARDGDA 365 Query: 717 GPNAVVHYSI-KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW 775 N V YSI + D ++F ++ G+ +V +D + + A L Sbjct: 366 FDNP-VRYSIDRRSDAISAFRIDPNNGT--VTVVQPLDRETSAWHNFSAEAKETAQGRLS 422 Query: 776 NDVRVEILVTDVNDNAP-VMKDFQ 798 + V++ I V D+NDN P + +D+Q Sbjct: 423 SSVKLFIKVLDINDNVPRLARDYQ 446 Score = 173 bits (420), Expect = 8e-41 Identities = 148/482 (30%), Positives = 222/482 (46%), Gaps = 34/482 (7%) Query: 283 DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG- 341 D+D G + + Y ++ + G DL ID +G ++ +LDRE +A Y L A + Sbjct: 32 DSDRG-ESSIRYILSGE---GAGDL-FQIDESTGEIWMLRKLDREEKASYVLQAQAINRR 86 Query: 342 GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE-----D 396 P + F YE + E P GT V +TATDAD+ + Sbjct: 87 SSQPEELQSEFIITVQDINDNVPLFQNEPYESSIPEMCPLGTTVARVTATDADDPMFGNN 146 Query: 397 NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD----SGGRSDT 452 +L Y I G FS+ + G ++T +D + +Y++ V A D SGG S + Sbjct: 147 AKLIYSILQGEPY--FSVEPKTGI-IVTSWPNMDREARDQYLVVVQAKDMLGLSGGHSSS 203 Query: 453 AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512 V +++TD N+ P F++ Y V E+A +GTTV + A D D+GINA+++YSL + Sbjct: 204 TTVTVSLTDVNDNGPTFQHHVYAFGVPENAAVGTTVGRIMAEDGDIGINAKMSYSLEDSL 263 Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA-------RDGGVPSLSDTT 565 V Q G + K LD ET ++L A R + D Sbjct: 264 EESGTFIIRTDPVT--QEGVVLLAKPLDFETKRRFVLAAEAVNDYPDTRFLPLDKFRDRM 321 Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDR 625 ++I V DV D PVF LY + E+ +VGT+V V A D D + + Y +D + Sbjct: 322 TLKIIVEDV-DEPPVFLHPLYEWKVPENVVVGTAVGSVSARDGDA-FDNPVRYSIDRRSD 379 Query: 626 EEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685 +F IDP +G + + LDRE+ A H+ A A + SS+V + IK+ DIND+ P Sbjct: 380 AISAFRIDPNNGTVTVVQPLDRETSAWHNFSAEAKETAQGRLSSSVKLFIKVLDINDNVP 439 Query: 686 VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN---SFSLETRQG 742 D YI E + G + I A DPDE P H+ D + +F+L QG Sbjct: 440 RLARDYQP-YICEGTQPGEPVQLISAVDPDE-PVEGHHFYFSMVPDRHINPNFTLRDNQG 497 Query: 743 SD 744 + Sbjct: 498 PE 499 Score = 158 bits (384), Expect = 2e-36 Identities = 133/470 (28%), Positives = 223/470 (47%), Gaps = 38/470 (8%) Query: 170 VIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA 229 VI ++++ D+D G S+IRY + G F ID +G++ +++ LD E+ SY L +A Sbjct: 25 VIGQLRS-DSDRG-ESSIRYILSGEGAGDLFQIDESTGEIWMLRKLDREEKASYVLQAQA 82 Query: 230 -QDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE-- 286 S ++ +I ++D+NDN P F ++ S+ E P+G ++ RV A DAD+ Sbjct: 83 INRRSSQPEELQSEFIITVQDINDNVPLFQNEPYESSIPEMCPLGTTVARVTATDADDPM 142 Query: 287 -GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS-GQLDRETQAKYQLLVTATD--GG 342 G NA+L Y++ + +++P++G + TS +DRE + +Y ++V A D G Sbjct: 143 FGNNAKLIYSILQGEPY------FSVEPKTGIIVTSWPNMDREARDQYLVVVQAKDMLGL 196 Query: 343 DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLH 400 S++ T F Y + E+ GT V + A D D + ++ Sbjct: 197 SGGHSSSTTVTVSLTDVNDNGPTFQHHVYAFGVPENAAVGTTVGRIMAEDGDIGINAKMS 256 Query: 401 YEITGG-NTRGRFSITSQ--NGRGLITVAQPLDFKQERRYVLTVSATDSGGRS------- 450 Y + G F I + G++ +A+PLDF+ +RR+VL A + + Sbjct: 257 YSLEDSLEESGTFIIRTDPVTQEGVVLLAKPLDFETKRRFVLAAEAVNDYPDTRFLPLDK 316 Query: 451 --DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508 D ++I + D + PVF + Y V E+ +GT V VSA D D N + YS+ Sbjct: 317 FRDRMTLKIIVEDVDE-PPVFLHPLYEWKVPENVVVGTAVGSVSARDGDAFDN-PVRYSI 374 Query: 509 SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568 ++A++ F I+P G +T + LDRET + + + A++ LS + + Sbjct: 375 DRR--SDAIS----AFRIDPNNGTVTVVQPLDRETSAWHNFSAEAKETAQGRLSSSVKLF 428 Query: 569 ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHY 618 I V+D+NDN P + Y I E G V + A D D + G Y Sbjct: 429 IKVLDINDNVPRLARD-YQPYICEGTQPGEPVQLISAVDPDEPVEGHHFY 477 Score = 143 bits (347), Expect = 5e-32 Identities = 122/436 (27%), Positives = 200/436 (45%), Gaps = 26/436 (5%) Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 D+F+ID +G + LDRE+ A Y + +A ++ S + L S I V D NDN Sbjct: 51 DLFQIDESTGEIWMLRKLDREEKASYVLQAQAINRRSSQPEELQSEFIITVQ--DINDNV 108 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD---VGANSAIRYAIIGGNTQMQFSIDS 204 P F + Y S+ E + +A++ ATDAD G N+ + Y+I+ G + FS++ Sbjct: 109 PLFQNEPYESSIPEMCPL--GTTVARVTATDADDPMFGNNAKLIYSILQG--EPYFSVEP 164 Query: 205 LSGD-VSLVKTLDYEQVRSYRLVIRAQD--GGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261 +G V+ +D E Y +V++A+D G S S++T + +++ DVNDN P F + Sbjct: 165 KTGIIVTSWPNMDREARDQYLVVVQAKDMLGLSGGHSSSTTVTVSLTDVNDNGPTFQHHV 224 Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK-DYTGNVDLPITIDPRSGWVYT 320 + V EN +G ++ R+ A D D G+NA+++Y++ D + +G + + G V Sbjct: 225 YAFGVPENAAVGTTVGRIMAEDGDIGINAKMSYSLEDSLEESGTFIIRTDPVTQEGVVLL 284 Query: 321 SGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX------XFMPGQYEVE 374 + LD ET+ ++ L A + R F+ YE + Sbjct: 285 AKPLDFETKRRFVLAAEAVNDYPDTRFLPLDKFRDRMTLKIIVEDVDEPPVFLHPLYEWK 344 Query: 375 LAEDEPPGTPVVTLTATDADE-DNRLHYEI-TGGNTRGRFSITSQNGRGLITVAQPLDFK 432 + E+ GT V +++A D D DN + Y I + F I N G +TV QPLD + Sbjct: 345 VPENVVVGTAVGSVSARDGDAFDNPVRYSIDRRSDAISAFRIDPNN--GTVTVVQPLDRE 402 Query: 433 QERRYVLTVSA--TDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 + + A T G S + + I + D N+ P Y + E G V + Sbjct: 403 TSAWHNFSAEAKETAQGRLSSSVKLFIKVLDINDNVPRLAR-DYQPYICEGTQPGEPVQL 461 Query: 491 VSATDSDVGINAQITY 506 +SA D D + Y Sbjct: 462 ISAVDPDEPVEGHHFY 477 Score = 120 bits (288), Expect = 8e-25 Identities = 115/407 (28%), Positives = 180/407 (44%), Gaps = 46/407 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVTA 67 I V D ND+ P+F+ + YE+S+ E GTTV + ATD D G NA++ Y+I Sbjct: 99 ITVQDINDNVPLFQNEPYESSIPEMCPLGTTVARVTATDADDPMFGNNAKLIYSI----- 153 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR-ASLDREKVARYTVLVKATDQASPV 126 L E F ++ ++G ++T ++DRE +Y V+V+A D + Sbjct: 154 --LQGE--------------PYFSVEPKTGIIVTSWPNMDREARDQYLVVVQAKDMLG-L 196 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 S SS+ T+ V++ D NDN P F Y V E+ +V + +I A D D+G N+ Sbjct: 197 SGGHSSSTTVTVSLTDVNDNGPTFQHHVYAFGVPENAAV--GTTVGRIMAEDGDIGINAK 254 Query: 187 IRYAI-----IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR---- 237 + Y++ G ++ + G V L K LD+E R + L A + +R Sbjct: 255 MSYSLEDSLEESGTFIIRTDPVTQEGVVLLAKPLDFETKRRFVLAAEAVNDYPDTRFLPL 314 Query: 238 ---SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294 + L I + DV D P F L++ V ENV +G ++ V A D D N + Y Sbjct: 315 DKFRDRMTLKIIVEDV-DEPPVFLHPLYEWKVPENVVVGTAVGSVSARDGDAFDN-PVRY 372 Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354 ++ D + IDP +G V LDRET A + A + R +++ Sbjct: 373 SI---DRRSDAISAFRIDPNNGTVTVVQPLDRETSAWHNFSAEAKETAQ-GRLSSSVKLF 428 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHY 401 + Y+ + E PG PV ++A D DE H+ Sbjct: 429 IKVLDINDNVPRLARDYQPYICEGTQPGEPVQLISAVDPDEPVEGHH 475 Score = 95.9 bits (228), Expect = 1e-17 Identities = 79/289 (27%), Positives = 128/289 (44%), Gaps = 24/289 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +++ D ND+ P F+ Y V E A+ GTTV + A D DIG NA++ Y++E D+L Sbjct: 208 VSLTDVNDNGPTFQHHVYAFGVPENAAVGTTVGRIMAEDGDIGINAKMSYSLE----DSL 263 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS--- 127 E++ Q+ G +L LD E R+ + +A + Sbjct: 264 --EESGTFIIRTDPVTQE--------GVVLLAKPLDFETKRRFVLAAEAVNDYPDTRFLP 313 Query: 128 -DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 D+ T+ + I++D D P F Y V E++ V + + A D D N Sbjct: 314 LDKFRDRMTLKI-IVEDVDEPPVFLHPLYEWKVPENVVV--GTAVGSVSARDGDAFDN-P 369 Query: 187 IRYAIIGGNTQMQ-FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 +RY+I + + F ID +G V++V+ LD E + A++ S++ +L I Sbjct: 370 VRYSIDRRSDAISAFRIDPNNGTVTVVQPLDRETSAWHNFSAEAKETAQGRLSSSVKLFI 429 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294 + D+NDN PR +Q + E G + + A D DE V Y Sbjct: 430 KVLDINDNVPRLARD-YQPYICEGTQPGEPVQLISAVDPDEPVEGHHFY 477 Score = 79.4 bits (187), Expect = 1e-12 Identities = 69/227 (30%), Positives = 114/227 (50%), Gaps = 17/227 (7%) Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG-GT 664 +D+D G I Y L + + F ID ++G I + LDRE A++ L+A AI+ + Sbjct: 31 SDSDRG-ESSIRYILSGEGAGD-LFQIDESTGEIWMLRKLDREEKASYVLQAQAINRRSS 88 Query: 665 PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE---GPNAV 721 P+ I ++DIND+ P+F+++ I E P+GTT+ + A D D+ G NA Sbjct: 89 QPEELQSEFIITVQDINDNVPLFQNEPYESSIPEMCPLGTTVARVTATDADDPMFGNNAK 148 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-----SPPLWN 776 + YSI G+ FS+E + G + + ++D E+ R +Y +V++A S + Sbjct: 149 LIYSILQGEPY--FSVEPKTG---IIVTSWPNMDREA-RDQYLVVVQAKDMLGLSGGHSS 202 Query: 777 DVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV 823 V + +TDVNDN P + F ++ GR+ A D D+ Sbjct: 203 STTVTVSLTDVNDNGPTFQHHVYAFGVPENAAVGTTVGRIMAEDGDI 249 >UniRef50_P55288 Cluster: Cadherin-11 precursor; n=28; Tetrapoda|Rep: Cadherin-11 precursor - Mus musculus (Mouse) Length = 796 Score = 179 bits (436), Expect = 9e-43 Identities = 157/540 (29%), Positives = 248/540 (45%), Gaps = 47/540 (8%) Query: 168 NPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVI 227 +PV+ +D D G + I+Y + G F ID SG++ KTLD E+ Y L+ Sbjct: 70 DPVLVGRLHSDIDSGDGN-IKYILSGEGAGTIFVIDDKSGNIHATKTLDREERAQYTLMA 128 Query: 228 RAQD-GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE 286 +A D + ++ ++ ++D+NDN P F ++ +V E +G S+++V A DAD+ Sbjct: 129 QAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHEIYHANVPERSNVGTSVIQVTASDADD 188 Query: 287 ---GVNAELTYTMTD-KDYTGNVDLPITIDPRSGWVYTS-GQLDRETQAKYQLLVTATDG 341 G +A+L Y++ + + Y +++ ++G + T+ +DRE + +Y +++ A D Sbjct: 189 PTYGNSAKLVYSILEGQPY-------FSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDM 241 Query: 342 GD--PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDN 397 G S T F Y++ ++E PG V + A D D E+ Sbjct: 242 GGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENG 301 Query: 398 RLHYEITGGNTRGRFSITS--QNGRGLITVAQPLDFKQERRYVLTVSATD---------S 446 + Y I G+ F IT+ + G++ + +P+DF+ +R Y L + A + + Sbjct: 302 LVTYNIVDGDGIELFEITTDYETQDGVVKLKKPVDFETKRAYSLKIEAANVHIDPKFISN 361 Query: 447 GGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506 G DT V+I++ DA+ P+F Y V E+A GT V V A D D N+ I Y Sbjct: 362 GPFKDTVTVKISVEDADE-PPMFLAPSYIHEVQENAAAGTVVGRVHAKDPDAA-NSPIRY 419 Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTD 566 S+ D+ F INP+ G I T K LDRE + ++V A + Sbjct: 420 SIDRH------TDLDRFFTINPEDGFIKTTKPLDREETAWLNISVFAAEIHNRHQETKVP 473 Query: 567 VEISVVDVNDNEPVFKQQLYTANIMED----ALVGTSVSQVGATDADVGLNG-RIHYELD 621 V I V+DVNDN P F Y I E AL + V A D D NG R + L Sbjct: 474 VAIRVLDVNDNAPKFAAP-YEGFICESDHPKALSNQPIVTVSADDQDDTANGPRFIFSLP 532 Query: 622 PKDREEGSFVI----DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 P+ +F + D +GV R+ + L V DGG PP SST + IK+ Sbjct: 533 PEIMHNPNFTVRDNRDNTAGVYARRGGFSRQKQDFYLLPIVISDGGIPPMSSTNTLTIKV 592 Score = 167 bits (406), Expect = 4e-39 Identities = 150/513 (29%), Positives = 237/513 (46%), Gaps = 40/513 (7%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +F ID +SG + +LDRE+ A+YT++ +A D+ + + L + V + D NDN P Sbjct: 100 IFVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDT--NRPLEPPSEFIVKVQDINDNPP 157 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDAD---VGANSAIRYAIIGGNTQMQFSIDSL 205 +F + Y +V E +V + + ++ A+DAD G ++ + Y+I+ G Q FS+++ Sbjct: 158 EFLHEIYHANVPERSNVGTS--VIQVTASDADDPTYGNSAKLVYSILEG--QPYFSVEAQ 213 Query: 206 SGDV-SLVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQLLINIRDVNDNAPRFYTSLF 262 +G + + + +D E Y +VI+A+D G S TT++ I + DVNDN P+F S++ Sbjct: 214 TGIIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVY 273 Query: 263 QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322 Q SVSE G + RV+A D D G N +TY + D D ++ + + G V Sbjct: 274 QMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYNIVDGDGIELFEITTDYETQDGVVKLKK 333 Query: 323 QLDRETQAKYQLLVTATDGGDPPRSAT------ATXXXXXXXXXXXXXXFMPGQYEVELA 376 +D ET+ Y L + A + P+ + F+ Y E+ Sbjct: 334 PVDFETKRAYSLKIEAANVHIDPKFISNGPFKDTVTVKISVEDADEPPMFLAPSYIHEVQ 393 Query: 377 EDEPPGTPVVTLTATDADEDNR-LHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435 E+ GT V + A D D N + Y I RF T G I +PLD ++ Sbjct: 394 ENAAAGTVVGRVHAKDPDAANSPIRYSIDRHTDLDRF-FTINPEDGFIKTTKPLDREETA 452 Query: 436 RYVLTVSATDSGGR-SDTAM-VQINITDANNYAPVFENAPYTASVFE-DAPIGTT---VL 489 ++V A + R +T + V I + D N+ AP F APY + E D P + ++ Sbjct: 453 WLNISVFAAEIHNRHQETKVPVAIRVLDVNDNAPKFA-APYEGFICESDHPKALSNQPIV 511 Query: 490 VVSATDSDVGINA-QITYSLSSEISNEAVAHHDQQFVINPQ----TGAITTNKLLDRETM 544 VSA D D N + +SL EI H+ F + G R+ Sbjct: 512 TVSADDQDDTANGPRFIFSLPPEIM------HNPNFTVRDNRDNTAGVYARRGGFSRQKQ 565 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISV--VDVN 575 YLL + DGG+P +S T + I V DVN Sbjct: 566 DFYLLPIVISDGGIPPMSSTNTLTIKVCGCDVN 598 Score = 156 bits (378), Expect = 9e-36 Identities = 128/430 (29%), Positives = 190/430 (44%), Gaps = 30/430 (6%) Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPPRSATATXXXXXXXXXXXXXXFMPG 369 ID +SG ++ + LDRE +A+Y L+ A D + P + F+ Sbjct: 103 IDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHE 162 Query: 370 QYEVELAEDEPPGTPVVTLTATDADEDN-----RLHYEITGGNTRGRFSITSQNGRGLIT 424 Y + E GT V+ +TA+DAD+ +L Y I G FS+ +Q G +I Sbjct: 163 IYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPY--FSVEAQTG--IIR 218 Query: 425 VAQP-LDFKQERRYVLTVSATDSGGR----SDTAMVQINITDANNYAPVFENAPYTASVF 479 A P +D + + Y + + A D GG S T V I +TD N+ P F + Y SV Sbjct: 219 TALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVS 278 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E A G V V A D D+G N +TY++ + + + + Q G + K + Sbjct: 279 EAAVPGEEVGRVKAKDPDIGENGLVTYNI---VDGDGIELFEITTDYETQDGVVKLKKPV 335 Query: 540 DRETMSGYLLTVTARDGGVPS-------LSDTTDVEISVVDVNDNEPVFKQQLYTANIME 592 D ET Y L + A + + DT V+ISV D D P+F Y + E Sbjct: 336 DFETKRAYSLKIEAANVHIDPKFISNGPFKDTVTVKISVEDA-DEPPMFLAPSYIHEVQE 394 Query: 593 DALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVAT 652 +A GT V +V A D D N I Y +D + F I+P G I+T K LDRE A Sbjct: 395 NAAAGTVVGRVHAKDPDAA-NSPIRYSIDRHTDLDRFFTINPEDGFIKTTKPLDREETAW 453 Query: 653 HDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT---IGEI 709 ++ A + Q + V V I++ D+ND+ P F + F + P + I + Sbjct: 454 LNISVFAAEIHNRHQETKVPVAIRVLDVNDNAPKFAAPYEGFICESDHPKALSNQPIVTV 513 Query: 710 RAHDPDEGPN 719 A D D+ N Sbjct: 514 SADDQDDTAN 523 Score = 148 bits (359), Expect = 2e-33 Identities = 130/432 (30%), Positives = 198/432 (45%), Gaps = 34/432 (7%) Query: 381 PGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL 439 P +V +D D D + Y ++G F I ++G I + LD ++ +Y L Sbjct: 69 PDPVLVGRLHSDIDSGDGNIKYILSGEGAGTIFVIDDKSGN--IHATKTLDREERAQYTL 126 Query: 440 TVSATDSGGR---SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDS 496 A D + + + D N+ P F + Y A+V E + +GT+V+ V+A+D+ Sbjct: 127 MAQAVDRDTNRPLEPPSEFIVKVQDINDNPPEFLHEIYHANVPERSNVGTSVIQVTASDA 186 Query: 497 DVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN-KLLDRETMSGYLLTVTARD 555 D TY S+++ ++ F + QTG I T +DRE Y + + A+D Sbjct: 187 D-----DPTYGNSAKLVY-SILEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKD 240 Query: 556 --GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN 613 G + LS TT V I++ DVNDN P F Q +Y ++ E A+ G V +V A D D+G N Sbjct: 241 MGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGEN 300 Query: 614 GRIHYEL---DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ--- 667 G + Y + D + E + + GV++ K +D E+ + LK A + P+ Sbjct: 301 GLVTYNIVDGDGIELFEITTDYETQDGVVKLKKPVDFETKRAYSLKIEAANVHIDPKFIS 360 Query: 668 ----SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 TV V I +ED D PP+F + + EN+ GT +G + A DPD N+ + Sbjct: 361 NGPFKDTVTVKISVEDA-DEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPD-AANSPIR 418 Query: 724 YSI-KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWND--VRV 780 YSI + D F++ G K T LD E V A + V V Sbjct: 419 YSIDRHTDLDRFFTINPEDGFIK----TTKPLDREETAWLNISVFAAEIHNRHQETKVPV 474 Query: 781 EILVTDVNDNAP 792 I V DVNDNAP Sbjct: 475 AIRVLDVNDNAP 486 Score = 124 bits (300), Expect = 3e-26 Identities = 102/324 (31%), Positives = 152/324 (46%), Gaps = 19/324 (5%) Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTA--RDGGVPSLSDTTDVEISVVDVNDNEPVF 581 FVI+ ++G I K LDRE + Y L A RD P L ++ + V D+NDN P F Sbjct: 101 FVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRP-LEPPSEFIVKVQDINDNPPEF 159 Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641 ++Y AN+ E + VGTSV QV A+DAD G + + F ++ +G+IRT Sbjct: 160 LHEIYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSILEGQPYFSVEAQTGIIRT 219 Query: 642 NKA-LDRESVATHDLKAVAID--GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698 +DRE+ + + A D G S T V I + D+ND+PP F +SE Sbjct: 220 ALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQSVYQMSVSE 279 Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES 758 + G +G ++A DPD G N +V Y+I GD F + T + + +D+E+ Sbjct: 280 AAVPGEEVGRVKAKDPDIGENGLVTYNIVDGDGIELFEITTDYETQDGVVKLKKPVDFET 339 Query: 759 PRKKYELVIRAA----------SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCF 808 ++ Y L I AA + P + V V+I V D D P+ I ++ Sbjct: 340 -KRAYSLKIEAANVHIDPKFISNGPFKDTVTVKISVEDA-DEPPMFLAPSYIHEVQENAA 397 Query: 809 PVGPFGRVPAYDADVTDK-LQYRI 831 GRV A D D + ++Y I Sbjct: 398 AGTVVGRVHAKDPDAANSPIRYSI 421 Score = 122 bits (294), Expect = 1e-25 Identities = 109/405 (26%), Positives = 181/405 (44%), Gaps = 51/405 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVTA 67 + V D ND+ P F + Y A+V E ++ GT+V+ + A+D D G +A++ Y+I Sbjct: 147 VKVQDINDNPPEFLHEIYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSI----- 201 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR-ASLDREKVARYTVLVKATDQASPV 126 Q F ++ ++G + T ++DRE Y V+++A D + Sbjct: 202 ----------------LEGQPYFSVEAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGHM 245 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 LS T + + + D NDN P+F + Y +SV E + + ++KA D D+G N Sbjct: 246 GG-LSGTTKVTITLTDVNDNPPKFPQSVYQMSVSE--AAVPGEEVGRVKAKDPDIGENGL 302 Query: 187 IRYAIIGGNTQMQFSI----DSLSGDVSLVKTLDYEQVRSYRLVIRAQD--------GGS 234 + Y I+ G+ F I ++ G V L K +D+E R+Y L I A + Sbjct: 303 VTYNIVDGDGIELFEITTDYETQDGVVKLKKPVDFETKRAYSLKIEAANVHIDPKFISNG 362 Query: 235 PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294 P + +T + I++ D D P F + V EN G + RV A D D N+ + Y Sbjct: 363 PFK-DTVTVKISVEDA-DEPPMFLAPSYIHEVQENAAAGTVVGRVHAKDPD-AANSPIRY 419 Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354 ++ D ++D TI+P G++ T+ LDRE A + V A + + + Sbjct: 420 SI---DRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNISVFAAEIHNRHQETKVPVAI 476 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPP----GTPVVTLTATDADE 395 F YE + E + P P+VT++A D D+ Sbjct: 477 RVLDVNDNAPKF-AAPYEGFICESDHPKALSNQPIVTVSADDQDD 520 Score = 101 bits (241), Expect = 4e-19 Identities = 97/352 (27%), Positives = 146/352 (41%), Gaps = 31/352 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D ND+ P F Y+ SV E A G V +KA D DIG+N V Y I V D + Sbjct: 256 ITLTDVNDNPPKFPQSVYQMSVSEAAVPGEEVGRVKAKDPDIGENGLVTYNI--VDGDGI 313 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT----DQASPV 126 QD G + + +D E Y++ ++A D Sbjct: 314 E-----LFEITTDYETQD--------GVVKLKKPVDFETKRAYSLKIEAANVHIDPKFIS 360 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 + T T+ ++ ++D D P F +Y V E+ + V+ ++ A D D ANS Sbjct: 361 NGPFKDTVTVKIS-VEDADEPPMFLAPSYIHEVQENAAA--GTVVGRVHAKDPD-AANSP 416 Query: 187 IRYAIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 IRY+ I +T + F+I+ G + K LD E+ + + A + + + + Sbjct: 417 IRYS-IDRHTDLDRFFTINPEDGFIKTTKPLDREETAWLNISVFAAEIHNRHQETKVPVA 475 Query: 245 INIRDVNDNAPRF---YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 I + DVNDNAP+F Y ES IV V A D D+ N + Sbjct: 476 IRVLDVNDNAPKFAAPYEGFICESDHPKALSNQPIVTVSADDQDDTANGPRFIFSLPPEI 535 Query: 302 TGNVDLPI--TIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 N + + D +G G R+ Q Y L + +DGG PP S+T T Sbjct: 536 MHNPNFTVRDNRDNTAGVYARRGGFSRQKQDFYLLPIVISDGGIPPMSSTNT 587 >UniRef50_UPI0000F20039 Cluster: PREDICTED: hypothetical protein; n=4; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 997 Score = 177 bits (431), Expect = 4e-42 Identities = 184/645 (28%), Positives = 284/645 (44%), Gaps = 69/645 (10%) Query: 10 QINVLDCNDHSPVF---------EMQQYEASVREGASSGTTV--LTLKATDQDIGKNAEV 58 QI++ D ND+SP F + +E +V E +S+G + L +K D D G+N+ Sbjct: 34 QISIKDENDNSPEFYECEGEACMKKDNFEGNVDEHSSTGLAIANLNIKVKDLDGGENSRF 93 Query: 59 EYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVK 118 ++ D VQ + + ++D E V + Sbjct: 94 NLHLDGPDKDAFR---VSPTSGMGESTVQVLVK---------DPQAVDYEIKQIMNVQII 141 Query: 119 ATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATD 178 A D + +STAT+ +++ D NDN+P F ++ Y V E + ++A I ATD Sbjct: 142 AVDANAD----FTSTATVTIHLNDTNDNFPTFEKELYKEKVFEHCE--NGTIVATITATD 195 Query: 179 ADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVK--TLDYEQVRSYRLVIRAQDGGSPS 236 AD I Y ++ + + F + +G + + TLD E +SY L ++A D G+ Sbjct: 196 ADAFDEGKITYKLMPESIRSLFGVHEKTGTIYVTNGDTLDREVTKSYTLTLQAFDSGN-- 253 Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDAD-EGVNAELTYT 295 + TT + I I D+NDNAP +++ V EN I D D + N + Y Sbjct: 254 NTGTTVVEILILDINDNAPEMNRDIYEAFVQENEDFKIQIQATDRDDPDPDTQNNIVQYR 313 Query: 296 MTDK-DYTGNVDLPITIDPRSGWVYTSGQLDRET-----QAKYQLLVTATDGGDPPRSAT 349 ++++ ++ N +ID GW+ G LDRE QL+V A+D G P S++ Sbjct: 314 ISEESSFSSN----FSIDLEHGWLTNKGDLDREAIDISQNGVIQLIVIASDLGTPSLSSS 369 Query: 350 ATXXXXXXXXXXXXXXFM-PGQYEVELAEDEPPGTPVVTLTATDADE---DNRLHYEITG 405 A ++ P YE + E G V + A DAD+ +NR+ + IT Sbjct: 370 AKVNISVGDANDNAPRYLDPSPYEFRVKE-SVKGIYVGPVHAHDADQTDFNNRIFFSITD 428 Query: 406 GNTRGRFSITSQ----NGRGLITV--AQPLDFKQERR-YVLTVSATDSGGRSDTAMVQIN 458 G+ G F I S+ RG ITV + LD++ R+ Y L V A+D G +SD A V I Sbjct: 429 GSF-GSFIIYSEAFSKGYRGNITVDPSVELDYESNRKEYTLKVQASDLGQKSDVAEVHII 487 Query: 459 ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE--ISNEA 516 + D N+ P F + V E+ + V + D D N + Y L S N Sbjct: 488 VEDVNDTPPEFPSG-MILKVDENTTLPVPVDTIKGKDVDT--NHSLIYELVSTKCQCNGT 544 Query: 517 VAHHDQQFVINPQTGAITTNK--LLDRETMSGYLLTVTARD--GGVPSLSDTTDVEISVV 572 + +++ I G I N ++D E LT D V S S V I++V Sbjct: 545 IGPCPEEWFIVESNGDIIANTEYVIDYEKCDVVFLTARVVDIYTEVGSNSSEGVVTINIV 604 Query: 573 DVNDNEP--VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR 615 D+NDN P VF Q Y ++E GTSV++ ATD D N + Sbjct: 605 DINDNAPEFVFLQDFYVV-VIEKVDTGTSVARAYATDRDTADNNK 648 Score = 167 bits (407), Expect = 3e-39 Identities = 132/460 (28%), Positives = 206/460 (44%), Gaps = 27/460 (5%) Query: 392 DADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA------QPLDFKQERRYVLTVSATD 445 D E++R + + G + + F ++ +G G TV Q +D++ ++ + + A D Sbjct: 86 DGGENSRFNLHLDGPD-KDAFRVSPTSGMGESTVQVLVKDPQAVDYEIKQIMNVQIIAVD 144 Query: 446 SGGR-SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504 + + TA V I++ D N+ P FE Y VFE GT V ++ATD+D +I Sbjct: 145 ANADFTSTATVTIHLNDTNDNFPTFEKELYKEKVFEHCENGTIVATITATDADAFDEGKI 204 Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT 564 TY L E H++ I +T LDRE Y LT+ A D G + + T Sbjct: 205 TYKLMPESIRSLFGVHEKTGTIY-----VTNGDTLDREVTKSYTLTLQAFDSG--NNTGT 257 Query: 565 TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL-NGRIHYELDPK 623 T VEI ++D+NDN P + +Y A + E+ + D D N + Y + + Sbjct: 258 TVVEILILDINDNAPEMNRDIYEAFVQENEDFKIQIQATDRDDPDPDTQNNIVQYRISEE 317 Query: 624 DREEGSFVIDPASGVIRTNKALDRESV-----ATHDLKAVAIDGGTPPQSSTVIVHIKIE 678 +F ID G + LDRE++ L +A D GTP SS+ V+I + Sbjct: 318 SSFSSNFSIDLEHGWLTNKGDLDREAIDISQNGVIQLIVIASDLGTPSLSSSAKVNISVG 377 Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP-NAVVHYSIKGGDDSNSFSL 737 D ND+ P + + + S G +G + AHD D+ N + +SI G + Sbjct: 378 DANDNAPRYLDPSPYEFRVKESVKGIYVGPVHAHDADQTDFNNRIFFSITDGSFGSFIIY 437 Query: 738 ETRQGSDKAELVTM---VDLDYESPRKKYELVIRAASPPLWNDV-RVEILVTDVNDNAPV 793 +T+ V+LDYES RK+Y L ++A+ +DV V I+V DVND P Sbjct: 438 SEAFSKGYRGNITVDPSVELDYESNRKEYTLKVQASDLGQKSDVAEVHIIVEDVNDTPPE 497 Query: 794 MKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILS 833 I+ + PV P + D D L Y ++S Sbjct: 498 FPSGMILKVDENTTLPV-PVDTIKGKDVDTNHSLIYELVS 536 Score = 145 bits (352), Expect = 1e-32 Identities = 146/515 (28%), Positives = 224/515 (43%), Gaps = 54/515 (10%) Query: 238 SNTTQLLINIRDVNDNAPRFYT---------SLFQESVSENVPIGYSI--VRVQAYDADE 286 S +L I+I+D NDN+P FY F+ +V E+ G +I + ++ D D Sbjct: 28 STIGELQISIKDENDNSPEFYECEGEACMKKDNFEGNVDEHSSTGLAIANLNIKVKDLDG 87 Query: 287 GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL--------DRETQAKYQLLVTA 338 G N+ + D + P SG ++ Q+ D E + + + A Sbjct: 88 GENSRFNLHLDGPDKDA-----FRVSPTSGMGESTVQVLVKDPQAVDYEIKQIMNVQIIA 142 Query: 339 TDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--ED 396 D + ++TAT F Y+ ++ E GT V T+TATDAD ++ Sbjct: 143 VDA-NADFTSTATVTIHLNDTNDNFPTFEKELYKEKVFEHCENGTIVATITATDADAFDE 201 Query: 397 NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ 456 ++ Y++ + R F + + G +T LD + + Y LT+ A DSG + T +V+ Sbjct: 202 GKITYKLMPESIRSLFGVHEKTGTIYVTNGDTLDREVTKSYTLTLQAFDSGNNTGTTVVE 261 Query: 457 INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI-NAQITYSLSSEISNE 515 I I D N+ AP Y A V E+ + D D N + Y +S E S Sbjct: 262 ILILDINDNAPEMNRDIYEAFVQENEDFKIQIQATDRDDPDPDTQNNIVQYRISEESS-- 319 Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRE----TMSGYL-LTVTARDGGVPSLSDTTDVEIS 570 F I+ + G +T LDRE + +G + L V A D G PSLS + V IS Sbjct: 320 ----FSSNFSIDLEHGWLTNKGDLDREAIDISQNGVIQLIVIASDLGTPSLSSSAKVNIS 375 Query: 571 VVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD-VGLNGRIHYELDPKDREEGS 629 V D NDN P + +++++ G V V A DAD N RI + + D GS Sbjct: 376 VGDANDNAPRYLDPSPYEFRVKESVKGIYVGPVHAHDADQTDFNNRIFFSI--TDGSFGS 433 Query: 630 FVI--DPASGVIRTNKALD-------RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDI 680 F+I + S R N +D + + LK A D G +S VHI +ED+ Sbjct: 434 FIIYSEAFSKGYRGNITVDPSVELDYESNRKEYTLKVQASDLG--QKSDVAEVHIIVEDV 491 Query: 681 NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 ND+PP F S + + EN+ + + I+ D D Sbjct: 492 NDTPPEFPSG-MILKVDENTTLPVPVDTIKGKDVD 525 Score = 128 bits (308), Expect = 3e-27 Identities = 171/619 (27%), Positives = 270/619 (43%), Gaps = 104/619 (16%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I++ D ND+ P FE + Y+ V E +GT V T+ ATD D ++ Y L Sbjct: 157 IHLNDTNDNFPTFEKELYKEKVFEHCENGTIVATITATDADAFDEGKITYK--------L 208 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRA-SLDREKVARYTVLVKATDQASPVSD 128 PE ++ +F + ++G + +T +LDRE YT+ ++A D S Sbjct: 209 MPES-----------IRSLFGVHEKTGTIYVTNGDTLDREVTKSYTLTLQAFD-----SG 252 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD----VGAN 184 + T + + I+D NDN P+ + Y V E+ D + +I+ATD D N Sbjct: 253 NNTGTTVVEILILDINDNAPEMNRDIYEAFVQEN---EDFKI--QIQATDRDDPDPDTQN 307 Query: 185 SAIRYAIIGGNT-QMQFSID------SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR 237 + ++Y I ++ FSID + GD+ + +D Q +L++ A D G+PS Sbjct: 308 NIVQYRISEESSFSSNFSIDLEHGWLTNKGDLDR-EAIDISQNGVIQLIVIASDLGTPSL 366 Query: 238 SNTTQLLINIRDVNDNAPRFY-TSLFQESVSENVPIGYSIVRVQAYDADE-GVNAELTYT 295 S++ ++ I++ D NDNAPR+ S ++ V E+V G + V A+DAD+ N + ++ Sbjct: 367 SSSAKVNISVGDANDNAPRYLDPSPYEFRVKESVK-GIYVGPVHAHDADQTDFNNRIFFS 425 Query: 296 MTD--------------KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK-YQLLVTATD 340 +TD K Y GN IT+DP S +LD E+ K Y L V A+D Sbjct: 426 ITDGSFGSFIIYSEAFSKGYRGN----ITVDP-------SVELDYESNRKEYTLKVQASD 474 Query: 341 GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH 400 G +S A F G +++ E+ PV T+ D D ++ L Sbjct: 475 LGQ--KSDVAEVHIIVEDVNDTPPEFPSGMI-LKVDENTTLPVPVDTIKGKDVDTNHSLI 531 Query: 401 YEI---------TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA----TDSG 447 YE+ T G + I NG + +D+++ LT T+ G Sbjct: 532 YELVSTKCQCNGTIGPCPEEWFIVESNGDIIANTEYVIDYEKCDVVFLTARVVDIYTEVG 591 Query: 448 GRSDTAMVQINITDANNYAPVFE-NAPYTASVFEDAPIGTTVLVVSATDSDVGIN----- 501 S +V INI D N+ AP F + V E GT+V ATD D N Sbjct: 592 SNSSEGVVTINIVDINDNAPEFVFLQDFYVVVIEKVDTGTSVARAYATDRDTADNNKKTK 651 Query: 502 ---AQITYSLSSEISNEAV----AHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554 +IT+ S + E++ + DQ+ T I + K +D +++ V A Sbjct: 652 FQVNKITFIGSEGNTTESLFLYADNFDQEDAEGRYTAYIRSQKAMDNNKRGKFMVEVEAV 711 Query: 555 DGGVPSLSDTTDVEISVVD 573 +G LS T VE+ VD Sbjct: 712 NG---KLSTTGVVELLTVD 727 Score = 124 bits (298), Expect = 5e-26 Identities = 185/700 (26%), Positives = 287/700 (41%), Gaps = 71/700 (10%) Query: 119 ATDQASPVSDRLSST-ATIHVNIIDDNDNYPQFSE---------KTYTVSVDEDISVTDN 168 A++ V++ ++ST + ++I D+NDN P+F E + +VDE S Sbjct: 15 ASETMPNVNEVIASTIGELQISIKDENDNSPEFYECEGEACMKKDNFEGNVDEHSSTGLA 74 Query: 169 PVIAKIKATDADVGANSAIRYAIIGGNTQ-MQFSIDSLSGDVS---LVK---TLDYEQVR 221 IK D D G NS + G + + S S G+ + LVK +DYE + Sbjct: 75 IANLNIKVKDLDGGENSRFNLHLDGPDKDAFRVSPTSGMGESTVQVLVKDPQAVDYEIKQ 134 Query: 222 SYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA 281 + I A D + S T + I++ D NDN P F L++E V E+ G + + A Sbjct: 135 IMNVQIIAVDANADFTSTAT-VTIHLNDTNDNFPTFEKELYKEKVFEHCENGTIVATITA 193 Query: 282 YDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY-TSGQ-LDRETQAKYQLLVTAT 339 DAD ++TY + + ++ + ++G +Y T+G LDRE Y L + A Sbjct: 194 TDADAFDEGKITYKLMPE----SIRSLFGVHEKTGTIYVTNGDTLDREVTKSYTLTLQAF 249 Query: 340 DGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED--- 396 D G+ + T YE + E+E + D D D Sbjct: 250 DSGN--NTGTTVVEILILDINDNAPEMNRDIYEAFVQENEDFKIQIQATDRDDPDPDTQN 307 Query: 397 NRLHYEITGGNT-RGRFSITSQNG----RGLITVAQPLDFKQERRYVLTVSATDSG--GR 449 N + Y I+ ++ FSI ++G +G + + +D Q L V A+D G Sbjct: 308 NIVQYRISEESSFSSNFSIDLEHGWLTNKGDLD-REAIDISQNGVIQLIVIASDLGTPSL 366 Query: 450 SDTAMVQINITDANNYAPVF-ENAPYTASVFEDAPIGTTVLVVSATDSD-VGINAQITYS 507 S +A V I++ DAN+ AP + + +PY V E G V V A D+D N +I +S Sbjct: 367 SSSAKVNISVGDANDNAPRYLDPSPYEFRVKESVK-GIYVGPVHAHDADQTDFNNRIFFS 425 Query: 508 LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG---YLLTVTARDGGVPSLSDT 564 ++ + + + G IT + ++ + S Y L V A D G SD Sbjct: 426 ITDGSFGSFIIY--SEAFSKGYRGNITVDPSVELDYESNRKEYTLKVQASDLG--QKSDV 481 Query: 565 TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-DPK 623 +V I V DVND P F + + E+ + V + D D N + YEL K Sbjct: 482 AEVHIIVEDVNDTPPEFPSGM-ILKVDENTTLPVPVDTIKGKDVDT--NHSLIYELVSTK 538 Query: 624 DREEGS--------FVIDPASGVI-RTNKALDRESVATHDLKAVAIDGGTP--PQSSTVI 672 + G+ F+++ +I T +D E L A +D T SS + Sbjct: 539 CQCNGTIGPCPEEWFIVESNGDIIANTEYVIDYEKCDVVFLTARVVDIYTEVGSNSSEGV 598 Query: 673 VHIKIEDINDSPP--VFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD 730 V I I DIND+ P VF D I E GT++ A D D N + K Sbjct: 599 VTINIVDINDNAPEFVFLQDFYVVVI-EKVDTGTSVARAYATDRDTADN-----NKKTKF 652 Query: 731 DSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVIRA 769 N + +G+ L D D E +Y IR+ Sbjct: 653 QVNKITFIGSEGNTTESLFLYADNFDQEDAEGRYTAYIRS 692 Score = 41.5 bits (93), Expect = 0.32 Identities = 34/137 (24%), Positives = 65/137 (47%), Gaps = 11/137 (8%) Query: 11 INVLDCNDHSPVFE-MQQYEASVREGASSGTTVLTLKATDQDIG-KNAEVEYTIELVTAD 68 IN++D ND++P F +Q + V E +GT+V ATD+D N + ++ + +T Sbjct: 601 INIVDINDNAPEFVFLQDFYVVVIEKVDTGTSVARAYATDRDTADNNKKTKFQVNKIT-- 658 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALL-TRASLDREKVARYTVLVKATDQASPVS 127 + E D +GR A + ++ ++D K ++ V V+A V+ Sbjct: 659 FIGSEGNTTESLFLYADNFDQEDAEGRYTAYIRSQKAMDNNKRGKFMVEVEA------VN 712 Query: 128 DRLSSTATIHVNIIDDN 144 +LS+T + + +D + Sbjct: 713 GKLSTTGVVELLTVDSS 729 >UniRef50_UPI0000E20B3B Cluster: PREDICTED: similar to Protocadherin gamma A2 precursor (PCDH-gamma-A2) isoform 4; n=3; Catarrhini|Rep: PREDICTED: similar to Protocadherin gamma A2 precursor (PCDH-gamma-A2) isoform 4 - Pan troglodytes Length = 878 Score = 172 bits (418), Expect = 1e-40 Identities = 113/362 (31%), Positives = 180/362 (49%), Gaps = 14/362 (3%) Query: 370 QYEVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQ---NGRGLITV 425 + E++++E PG + A DAD +N L N + S N + + Sbjct: 137 ELELKISETTTPGFRIPLKNAHDADVGENALQKYALNPNDHFSLDVRSGADGNKYPELVL 196 Query: 426 AQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 + LD ++E + L + A+D G S T+ + + + DAN+ APVF Y S+ E+ P Sbjct: 197 ERALDREEEAVHHLVLVASDGGDPVLSGTSRICVKVLDANDNAPVFTQPEYRISIPENTP 256 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 +GT +L V+ATD+D G AQ+ Y L ++ + F + +G +T K LD E Sbjct: 257 VGTRILTVTATDADEGYYAQVVYFLE-----KSPGETSEVFELKSTSGELTIIKDLDYED 311 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 + + + + A+DG P L V ++V+DVNDN P F T+++ ED+L GT + Sbjct: 312 ATFHEIDIEAQDG--PGLLTRAKVIVTVLDVNDNAPEFYMTSATSSVSEDSLPGTIIGLF 369 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 D D G N L + +D ++ T +ALDRE + +++ A DGG Sbjct: 370 NVHDRDSGQNAFTTCSLPENLPFKLEKSVDNYYRLV-TTRALDREQFSFYNITLTAKDGG 428 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 P S+ + +++ DIND+ P F + YI EN+P G ++ + AHDPD NA V Sbjct: 429 NPSLSTDAHILLQVADINDNAPAFSRTSYSTYIPENNPRGASVFSVTAHDPDSNDNAHVT 488 Query: 724 YS 725 YS Sbjct: 489 YS 490 Score = 167 bits (407), Expect = 3e-39 Identities = 124/403 (30%), Positives = 192/403 (47%), Gaps = 48/403 (11%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ + D ND++P F +++ E + E + G + A D D+G+NA +Y Sbjct: 120 EVEITDINDNAPRFGVEELELKISETTTPGFRIPLKNAHDADVGENALQKY--------A 171 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGA-------LLTRASLDREKVARYTVLVKATDQ 122 LNP D F +D RSGA L+ +LDRE+ A + +++ A+D Sbjct: 172 LNPNDH--------------FSLDVRSGADGNKYPELVLERALDREEEAVHHLVLVASDG 217 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 PV LS T+ I V ++D NDN P F++ Y +S+ E+ V I + ATDAD G Sbjct: 218 GDPV---LSGTSRICVKVLDANDNAPVFTQPEYRISIPENTPVGTR--ILTVTATDADEG 272 Query: 183 ANSAIRYAI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT 240 + + Y + G T F + S SG+++++K LDYE + + I AQDG P Sbjct: 273 YYAQVVYFLEKSPGETSEVFELKSTSGELTIIKDLDYEDATFHEIDIEAQDG--PGLLTR 330 Query: 241 TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKD 300 ++++ + DVNDNAP FY + SVSE+ G I +D D G NA T ++ + Sbjct: 331 AKVIVTVLDVNDNAPEFYMTSATSSVSEDSLPGTIIGLFNVHDRDSGQNAFTTCSLPE-- 388 Query: 301 YTGNVDLPITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357 +LP ++ Y T+ LDRE + Y + +TA DGG+P S A Sbjct: 389 -----NLPFKLEKSVDNYYRLVTTRALDREQFSFYNITLTAKDGGNPSLSTDAHILLQVA 443 Query: 358 XXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH 400 F Y + E+ P G V ++TA D D ++ H Sbjct: 444 DINDNAPAFSRTSYSTYIPENNPRGASVFSVTAHDPDSNDNAH 486 Score = 159 bits (386), Expect = 1e-36 Identities = 139/484 (28%), Positives = 216/484 (44%), Gaps = 27/484 (5%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +F ++ RSG+L+T +DRE++ + + D+L+ ++ V I D NDN P Sbjct: 74 LFALNPRSGSLVTANRIDREELCAQSAPCLLNFNIL-LEDKLT-IYSVEVEITDINDNAP 131 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG- 207 +F + + + E + T I A DADVG N+ +YA+ N FS+D SG Sbjct: 132 RFGVEELELKISE--TTTPGFRIPLKNAHDADVGENALQKYAL---NPNDHFSLDVRSGA 186 Query: 208 ------DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSL 261 ++ L + LD E+ + LV+ A DGG P S T+++ + + D NDNAP F Sbjct: 187 DGNKYPELVLERALDREEEAVHHLVLVASDGGDPVLSGTSRICVKVLDANDNAPVFTQPE 246 Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321 ++ S+ EN P+G I+ V A DADEG A++ Y + + G + SG + Sbjct: 247 YRISIPENTPVGTRILTVTATDADEGYYAQVVYFL--EKSPGETSEVFELKSTSGELTII 304 Query: 322 GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381 LD E +++ + A DG P A F ++ED P Sbjct: 305 KDLDYEDATFHEIDIEAQDG--PGLLTRAKVIVTVLDVNDNAPEFYMTSATSSVSEDSLP 362 Query: 382 GTPVVTLTATDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440 GT + D D N N + + N L+T + LD +Q Y +T Sbjct: 363 GTIIGLFNVHDRDSGQNAFTTCSLPENLPFKLEKSVDNYYRLVT-TRALDREQFSFYNIT 421 Query: 441 VSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDV 498 ++A D G S A + + + D N+ AP F Y+ + E+ P G +V V+A D D Sbjct: 422 LTAKDGGNPSLSTDAHILLQVADINDNAPAFSRTSYSTYIPENNPRGASVFSVTAHDPDS 481 Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINP--QTGAITTNKLLDRETMSGYLLT-VTA-- 553 NA +TYS + + + ++ P T T +L R GYL+T V A Sbjct: 482 NDNAHVTYSFVEDTVLVLDQNDNPPEILYPAFPTDGSTGVELAPRSAEPGYLVTKVVAVD 541 Query: 554 RDGG 557 RD G Sbjct: 542 RDSG 545 Score = 150 bits (364), Expect = 5e-34 Identities = 112/342 (32%), Positives = 163/342 (47%), Gaps = 14/342 (4%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 V++ ITD N+ AP F + E G + + +A D+DVG NA Y+L+ N Sbjct: 119 VEVEITDINDNAPRFGVEELELKISETTTPGFRIPLKNAHDADVGENALQKYALNP---N 175 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 + + + + + + LDRE + + L + A DGG P LS T+ + + V+D Sbjct: 176 DHFSLDVRSGADGNKYPELVLERALDREEEAVHHLVLVASDGGDPVLSGTSRICVKVLDA 235 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS-FVID 633 NDN PVF Q Y +I E+ VGT + V ATDAD G ++ Y L+ E F + Sbjct: 236 NDNAPVFTQPEYRISIPENTPVGTRILTVTATDADEGYYAQVVYFLEKSPGETSEVFELK 295 Query: 634 PASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693 SG + K LD E H++ A DG P + V + + D+ND+ P F T Sbjct: 296 STSGELTIIKDLDYEDATFHEIDIEAQDG--PGLLTRAKVIVTVLDVNDNAPEFYMTSAT 353 Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753 +SE+S GT IG HD D G NA S+ ++ F LE + + LVT Sbjct: 354 SSVSEDSLPGTIIGLFNVHDRDSGQNAFTTCSL---PENLPFKLE-KSVDNYYRLVTTRA 409 Query: 754 LDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAP 792 LD E Y + + A +P L D + + V D+NDNAP Sbjct: 410 LDREQ-FSFYNITLTAKDGGNPSLSTDAHILLQVADINDNAP 450 Score = 136 bits (329), Expect = 8e-30 Identities = 105/312 (33%), Positives = 142/312 (45%), Gaps = 20/312 (6%) Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTT-DVEISVVDVNDNEPV 580 Q F +NP++G++ T +DRE + + T VE+ + D+NDN P Sbjct: 73 QLFALNPRSGSLVTANRIDREELCAQSAPCLLNFNILLEDKLTIYSVEVEITDINDNAPR 132 Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV-- 638 F + I E G + A DADVG N Y L+P D F +D SG Sbjct: 133 FGVEELELKISETTTPGFRIPLKNAHDADVGENALQKYALNPNDH----FSLDVRSGADG 188 Query: 639 -----IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693 + +ALDRE A H L VA DGG P S T + +K+ D ND+ PVF Sbjct: 189 NKYPELVLERALDREEEAVHHLVLVASDGGDPVLSGTSRICVKVLDANDNAPVFTQPEYR 248 Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK--GGDDSNSFSLETRQGSDKAELVTM 751 I EN+P+GT I + A D DEG A V Y ++ G+ S F L++ G EL + Sbjct: 249 ISIPENTPVGTRILTVTATDADEGYYAQVVYFLEKSPGETSEVFELKSTSG----ELTII 304 Query: 752 VDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV 810 DLDYE +E+ I A P L +V + V DVNDNAP + +D P Sbjct: 305 KDLDYED-ATFHEIDIEAQDGPGLLTRAKVIVTVLDVNDNAPEFYMTSATSSVSEDSLPG 363 Query: 811 GPFGRVPAYDAD 822 G +D D Sbjct: 364 TIIGLFNVHDRD 375 Score = 134 bits (325), Expect = 3e-29 Identities = 90/289 (31%), Positives = 139/289 (48%), Gaps = 26/289 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 + VLD ND++PVF +Y S+ E GT +LT+ ATD D G A+V Y +E +T Sbjct: 230 VKVLDANDNAPVFTQPEYRISIPENTPVGTRILTVTATDADEGYYAQVVYFLEKSPGET- 288 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +VF + SG L LD E + + ++A D L Sbjct: 289 ----------------SEVFELKSTSGELTIIKDLDYEDATFHEIDIEAQDGPG-----L 327 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + A + V ++D NDN P+F + T SV ED +I D D G N+ + Sbjct: 328 LTRAKVIVTVLDVNDNAPEFYMTSATSSVSEDS--LPGTIIGLFNVHDRDSGQNAFTTCS 385 Query: 191 IIGGNT-QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 + +++ S+D+ V+ + LD EQ Y + + A+DGG+PS S +L+ + D Sbjct: 386 LPENLPFKLEKSVDNYYRLVT-TRALDREQFSFYNITLTAKDGGNPSLSTDAHILLQVAD 444 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 +NDNAP F + + + EN P G S+ V A+D D NA +TY+ + Sbjct: 445 INDNAPAFSRTSYSTYIPENNPRGASVFSVTAHDPDSNDNAHVTYSFVE 493 Score = 46.4 bits (105), Expect = 0.011 Identities = 28/117 (23%), Positives = 49/117 (41%), Gaps = 5/117 (4%) Query: 138 VNIIDDNDNYPQFSEKTYTVSVDEDISVTDNP-----VIAKIKATDADVGANSAIRYAII 192 V ++D NDN P+ + + + ++ K+ A D D G N+ + Y ++ Sbjct: 496 VLVLDQNDNPPEILYPAFPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYHLL 555 Query: 193 GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 + FS+ +G+V + L LV+ QD G P S T L + + D Sbjct: 556 KASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVAD 612 Score = 45.2 bits (102), Expect = 0.026 Identities = 39/136 (28%), Positives = 54/136 (39%), Gaps = 15/136 (11%) Query: 227 IRAQDGGSPSRSNTTQLLIN----IRDVNDNAPRFYTSLFQESVSENVPI-------GYS 275 + A D S ++ T + + D NDN P F S V + GY Sbjct: 474 VTAHDPDSNDNAHVTYSFVEDTVLVLDQNDNPPEILYPAFPTDGSTGVELAPRSAEPGYL 533 Query: 276 IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL 335 + +V A D D G NA L+Y + G + + +G V T+ L K L+ Sbjct: 534 VTKVVAVDRDSGQNAWLSYHLLKASEPGLFSVGL----HTGEVRTARALLDRDALKQSLV 589 Query: 336 VTATDGGDPPRSATAT 351 V D G PP SAT T Sbjct: 590 VAVQDHGQPPLSATVT 605 Score = 45.2 bits (102), Expect = 0.026 Identities = 38/119 (31%), Positives = 57/119 (47%), Gaps = 10/119 (8%) Query: 569 ISVVDVNDNEPVFKQQLYTAN-------IMEDALVGTSVSQVGATDADVGLNGRIHYELD 621 + V+D NDN P + + A G V++V A D D G N + Y L Sbjct: 496 VLVLDQNDNPPEILYPAFPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYHL- 554 Query: 622 PKDREEGSFVIDPASGVIRTNKAL-DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679 K E G F + +G +RT +AL DR+++ + AV D G PP S+TV + + + D Sbjct: 555 LKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQ-DHGQPPLSATVTLTVAVAD 612 Score = 40.7 bits (91), Expect = 0.57 Identities = 21/67 (31%), Positives = 30/67 (44%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 H + V D ND++P F Y + E G +V ++ A D D NA V Y+ T Sbjct: 437 HILLQVADINDNAPAFSRTSYSTYIPENNPRGASVFSVTAHDPDSNDNAHVTYSFVEDTV 496 Query: 68 DTLNPED 74 L+ D Sbjct: 497 LVLDQND 503 Score = 37.1 bits (82), Expect = 7.0 Identities = 30/90 (33%), Positives = 42/90 (46%), Gaps = 9/90 (10%) Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK-LLDRET 543 G V V A D D G NA ++Y L A F + TG + T + LLDR+ Sbjct: 531 GYLVTKVVAVDRDSGQNAWLSYHLLK-------ASEPGLFSVGLHTGEVRTARALLDRDA 583 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 + L+ V +D G P LS T + ++V D Sbjct: 584 LKQSLV-VAVQDHGQPPLSATVTLTVAVAD 612 >UniRef50_Q6V1P8 Cluster: Protocadherin protein; n=6; Catarrhini|Rep: Protocadherin protein - Homo sapiens (Human) Length = 702 Score = 172 bits (418), Expect = 1e-40 Identities = 141/433 (32%), Positives = 203/433 (46%), Gaps = 43/433 (9%) Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 D+ L++ LD E+ ++RL I A DGG P R+ + + + D NDN P F ++ +V Sbjct: 240 DLVLLRRLDREEAAAHRLQIEAWDGGRPRRTGLLSVELRVLDENDNPPVFEQDEYRAAVR 299 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD--------LPITIDPRSGWVY 319 E+ G + RV+A D D G N + Y++ + G ++ SG V Sbjct: 300 EDAQPGAEVCRVRATDRDLGPNGFVRYSVRARQVPGAGSGGGALGDAAYFAVEELSGVVR 359 Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXX----XXXXXFMPGQYEVEL 375 LDRE QA +QL+V A DGG P AT F+ + Sbjct: 360 VWRPLDREAQAWHQLVVEARDGGAEPEVATVRVSIAVLDVNDNRPAIHVLFLTEGGVARV 419 Query: 376 AEDEPPGTPVVTLTATDADEDNRLHYEITG----GNTRGRFSITSQNGRG---------- 421 +E PG V ++ +DAD D E TG G G S++ + G G Sbjct: 420 SEGARPGDYVARVSVSDADGDWEKEDEATGELGVGLGDGSISLSLEGGEGDFALLPGGPP 479 Query: 422 ---LITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTA 476 + V PLD + Y L + ATD+G S + + + D N+ P+F Y A Sbjct: 480 GVFFLCVEGPLDRESRDLYELLLVATDAGSPPLSTEETLLLRVADLNDQPPLFSQQHYKA 539 Query: 477 SVFEDAPIGTTVLVVSATDSDVG--INAQITYS---LSS-----EISNEAV--AHHDQQF 524 SV E A GT V+ VSA+D+D +A + Y+ LS+ + ++ V A F Sbjct: 540 SVSEAAAPGTVVMWVSASDADEAGSDHAWLRYTVVQLSAPCNLGSLQSKMVHTAECGPSF 599 Query: 525 VINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQ 584 I+ ++GAI+T + LDRE L V A+D G P LS T V I+V DVNDNEP+F +Q Sbjct: 600 AIDSESGAISTIRTLDREVQEAVELKVVAQDLGEPPLSATCLVSITVDDVNDNEPIFWRQ 659 Query: 585 LYTANIMEDALVG 597 +Y A I E A VG Sbjct: 660 VYNATIAEHAPVG 672 Score = 161 bits (392), Expect = 2e-37 Identities = 149/543 (27%), Positives = 233/543 (42%), Gaps = 61/543 (11%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 + +I V D NDHSP F + + V E + GT A D D G + YT+ + Sbjct: 144 VQVEIRVNDVNDHSPRFPLDSLQLDVSELSPPGTAFRLPVAHDPDAGLFSTQGYTLVQPS 203 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-----LTRASLDREKVARYTVLVKATD 121 +P + G S L + LDRE+ A + + ++A D Sbjct: 204 DLPKDPAGPFFQLRYRTPGPLPSPLLPGSSSPLEPLDLVLLRRLDREEAAAHRLQIEAWD 263 Query: 122 QASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV 181 P R + ++ + ++D+NDN P F + Y +V ED + +++ATD D+ Sbjct: 264 GGRP---RRTGLLSVELRVLDENDNPPVFEQDEYRAAVREDAQ--PGAEVCRVRATDRDL 318 Query: 182 GANSAIRYAI---------IGGNT---QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA 229 G N +RY++ GG F+++ LSG V + + LD E ++LV+ A Sbjct: 319 GPNGFVRYSVRARQVPGAGSGGGALGDAAYFAVEELSGVVRVWRPLDREAQAWHQLVVEA 378 Query: 230 QDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQES----VSENVPIGYSIVRVQAYDAD 285 +DGG+ T ++ I + DVNDN P + E VSE G + RV DAD Sbjct: 379 RDGGAEPEVATVRVSIAVLDVNDNRPAIHVLFLTEGGVARVSEGARPGDYVARVSVSDAD 438 Query: 286 ------EGVNAELTYTMTDKDYT-----GNVDLPITIDPRSG--WVYTSGQLDRETQAKY 332 + EL + D + G D + G ++ G LDRE++ Y Sbjct: 439 GDWEKEDEATGELGVGLGDGSISLSLEGGEGDFALLPGGPPGVFFLCVEGPLDRESRDLY 498 Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392 +LL+ ATD G PP S T F Y+ ++E PGT V+ ++A+D Sbjct: 499 ELLLVATDAGSPPLSTEETLLLRVADLNDQPPLFSQQHYKASVSEAAAPGTVVMWVSASD 558 Query: 393 ADEDNR----LHYEITG-------GNTRGRFSITSQNG--------RGLITVAQPLDFKQ 433 ADE L Y + G+ + + T++ G G I+ + LD + Sbjct: 559 ADEAGSDHAWLRYTVVQLSAPCNLGSLQSKMVHTAECGPSFAIDSESGAISTIRTLDREV 618 Query: 434 ERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL-V 490 + L V A D G S T +V I + D N+ P+F Y A++ E AP+G L + Sbjct: 619 QEAVELKVVAQDLGEPPLSATCLVSITVDDVNDNEPIFWRQVYNATIAEHAPVGHCFLQL 678 Query: 491 VSA 493 +SA Sbjct: 679 ISA 681 Score = 156 bits (379), Expect = 7e-36 Identities = 162/570 (28%), Positives = 242/570 (42%), Gaps = 72/570 (12%) Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259 F + +G + + LD E+ Y V G Q+ I + DVND++PRF Sbjct: 109 FHVHPDTGIIRTARRLDRERRDHYSFVAATLLGA------VVQVEIRVNDVNDHSPRFPL 162 Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD-----KDYTGNV--------- 305 Q VSE P G + A+D D G+ + YT+ KD G Sbjct: 163 DSLQLDVSELSPPGTAFRLPVAHDPDAGLFSTQGYTLVQPSDLPKDPAGPFFQLRYRTPG 222 Query: 306 DLPITIDPRSGW------VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 LP + P S + +LDRE A ++L + A DGG P R+ + Sbjct: 223 PLPSPLLPGSSSPLEPLDLVLLRRLDREEAAAHRLQIEAWDGGRPRRTGLLSVELRVLDE 282 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEI---------TGGNT 408 F +Y + ED PG V + ATD D + + Y + +GG Sbjct: 283 NDNPPVFEQDEYRAAVREDAQPGAEVCRVRATDRDLGPNGFVRYSVRARQVPGAGSGGGA 342 Query: 409 RGRFSITS-QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNY 465 G + + + G++ V +PLD + + + L V A D G + A V+++I D N+ Sbjct: 343 LGDAAYFAVEELSGVVRVWRPLDREAQAWHQLVVEARDGGAEPEVATVRVSIAVLDVNDN 402 Query: 466 AP----VFENAPYTASVFEDAPIGTTVLVVSATDSDVG------INAQITYSLSSEISNE 515 P +F A V E A G V VS +D+D ++ L + Sbjct: 403 RPAIHVLFLTEGGVARVSEGARPGDYVARVSVSDADGDWEKEDEATGELGVGLGDGSISL 462 Query: 516 AVAHHDQQFVINP--QTGA--ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV 571 ++ + F + P G + LDRE+ Y L + A D G P LS + + V Sbjct: 463 SLEGGEGDFALLPGGPPGVFFLCVEGPLDRESRDLYELLLVATDAGSPPLSTEETLLLRV 522 Query: 572 VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD-------------VGLN----- 613 D+ND P+F QQ Y A++ E A GT V V A+DAD V L+ Sbjct: 523 ADLNDQPPLFSQQHYKASVSEAAAPGTVVMWVSASDADEAGSDHAWLRYTVVQLSAPCNL 582 Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673 G + ++ SF ID SG I T + LDRE +LK VA D G PP S+T +V Sbjct: 583 GSLQSKMVHTAECGPSFAIDSESGAISTIRTLDREVQEAVELKVVAQDLGEPPLSATCLV 642 Query: 674 HIKIEDINDSPPVFESDCLTFYISENSPIG 703 I ++D+ND+ P+F I+E++P+G Sbjct: 643 SITVDDVNDNEPIFWRQVYNATIAEHAPVG 672 Score = 139 bits (336), Expect = 1e-30 Identities = 129/419 (30%), Positives = 191/419 (45%), Gaps = 52/419 (12%) Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAM--VQINITDANNYAPVFENAPYTASVFE 480 + + + LD ++ + L + A D G T + V++ + D N+ PVFE Y A+V E Sbjct: 241 LVLLRRLDREEAAAHRLQIEAWDGGRPRRTGLLSVELRVLDENDNPPVFEQDEYRAAVRE 300 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEI-----SNEAVAHHDQQFVINPQTGAITT 535 DA G V V ATD D+G N + YS+ + S F + +G + Sbjct: 301 DAQPGAEVCRVRATDRDLGPNGFVRYSVRARQVPGAGSGGGALGDAAYFAVEELSGVVRV 360 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYT----ANIM 591 + LDRE + + L V ARDGG T V I+V+DVNDN P T A + Sbjct: 361 WRPLDREAQAWHQLVVEARDGGAEPEVATVRVSIAVLDVNDNRPAIHVLFLTEGGVARVS 420 Query: 592 EDALVGTSVSQVGATDAD--------------VGL-NGRIHYELDPKDREEGSFVIDPAS 636 E A G V++V +DAD VGL +G I L+ EG F + P Sbjct: 421 EGARPGDYVARVSVSDADGDWEKEDEATGELGVGLGDGSISLSLEGG---EGDFALLPGG 477 Query: 637 --GV--IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL 692 GV + LDRES ++L VA D G+PP S+ + +++ D+ND PP+F Sbjct: 478 PPGVFFLCVEGPLDRESRDLYELLLVATDAGSPPLSTEETLLLRVADLNDQPPLFSQQHY 537 Query: 693 TFYISENSPIGTTIGEIRAHDPDE--GPNAVVHYS-IKGGDDSNSFSLETRQ-------- 741 +SE + GT + + A D DE +A + Y+ ++ N SL+++ Sbjct: 538 KASVSEAAAPGTVVMWVSASDADEAGSDHAWLRYTVVQLSAPCNLGSLQSKMVHTAECGP 597 Query: 742 ----GSDKAELVTMVDLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDVNDNAPV 793 S+ + T+ LD E ++ EL + A PPL V I V DVNDN P+ Sbjct: 598 SFAIDSESGAISTIRTLDRE-VQEAVELKVVAQDLGEPPLSATCLVSITVDDVNDNEPI 655 Score = 99 bits (238), Expect = 9e-19 Identities = 99/307 (32%), Positives = 135/307 (43%), Gaps = 45/307 (14%) Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583 F ++P TG I T + LDRE Y G V VEI V DVND+ P F Sbjct: 109 FHVHPDTGIIRTARRLDRERRDHYSFVAATLLGAV------VQVEIRVNDVNDHSPRFPL 162 Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD-----PKD----------REEG 628 ++ E + GT+ A D D GL Y L PKD R G Sbjct: 163 DSLQLDVSELSPPGTAFRLPVAHDPDAGLFSTQGYTLVQPSDLPKDPAGPFFQLRYRTPG 222 Query: 629 ----------SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE 678 S ++P V+ + LDRE A H L+ A DGG P ++ + V +++ Sbjct: 223 PLPSPLLPGSSSPLEPLDLVLL--RRLDREEAAAHRLQIEAWDGGRPRRTGLLSVELRVL 280 Query: 679 DINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG----GDDSNS 734 D ND+PPVFE D + E++ G + +RA D D GPN V YS++ G S Sbjct: 281 DENDNPPVFEQDEYRAAVREDAQPGAEVCRVRATDRDLGPNGFVRYSVRARQVPGAGSGG 340 Query: 735 FSLETRQGSDKAELVTMV----DLDYESPRKKYELVIRA---ASPPLWNDVRVEILVTDV 787 +L EL +V LD E+ + ++LV+ A + P VRV I V DV Sbjct: 341 GALGDAAYFAVEELSGVVRVWRPLDREA-QAWHQLVVEARDGGAEPEVATVRVSIAVLDV 399 Query: 788 NDNAPVM 794 NDN P + Sbjct: 400 NDNRPAI 406 >UniRef50_Q9H159 Cluster: Cadherin-19 precursor; n=15; Tetrapoda|Rep: Cadherin-19 precursor - Homo sapiens (Human) Length = 772 Score = 171 bits (417), Expect = 2e-40 Identities = 145/505 (28%), Positives = 240/505 (47%), Gaps = 35/505 (6%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F ID R+G + LDRE+ + Y + + D A+ + S I V+ D NDN P+ Sbjct: 90 FIIDERTGDIYAIQKLDREERSLYILRAQVIDIATGRAVEPESEFVIKVS--DINDNEPK 147 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDAD---VGANSAIRYAIIGGNTQMQFSIDSLS 206 F ++ Y V E + ++ ++ A+DAD G N+ + Y+++ G Q FS++ + Sbjct: 148 FLDEPYEAIVPE--MSPEGTLVIQVTASDADDPSSGNNARLLYSLLQG--QPYFSVEPTT 203 Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDG-GSPSR-SNTTQLLINIRDVNDNAPRFYTSLFQE 264 G + + +D E Y ++I+A+D G P S TT +LI + DVNDN P F SL++ Sbjct: 204 GVIRISSKMDRELQDEYWVIIQAKDMIGQPGALSGTTSVLIKLSDVNDNKPIFKESLYRL 263 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 +VSE+ P G SI + AYD D G NAE+ Y++ ++D + D+ + + G V ++ Sbjct: 264 TVSESAPTGTSIGTIMAYDNDIGENAEMDYSI-EEDDSQTFDIITNHETQEGIVILKKKV 322 Query: 325 DRETQAKYQLLVTATDGGDPPR------SATATXXXXXXXXXXXXXXFMPGQYEVELAED 378 D E Q Y + + P + A+ T F+ Y E+ E+ Sbjct: 323 DFEHQNHYGIRAKVKNHHVPEQLMKYHTEASTTFIKIQVEDVDEPPLFLLPYYVFEVFEE 382 Query: 379 EPPGTPVVTLTATDAD-EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437 P G+ V ++ATD D + + Y IT R + + N G IT + LD + Y Sbjct: 383 TPQGSFVGVVSATDPDNRKSPIRYSIT------RSKVFNINDNGTITTSNSLDREISAWY 436 Query: 438 VLTVSATDSGGRSDTAMV--QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495 L+++AT+ + + + + + N++AP F Y V E+A G + +SA D Sbjct: 437 NLSITATEKYNIEQISSIPLYVQVLNINDHAPEFSQY-YETYVCENAGSGQVIQTISAVD 495 Query: 496 SDVGINAQITY-SLSSE-ISNEAVAHHDQQFVINPQTGAITTNKL-LDRETMSGYLLTVT 552 D I Y +LS E +N + D Q T I TN+ + + + +++ Sbjct: 496 RDESIEEHHFYFNLSVEDTNNSSFTIIDNQ----DNTAVILTNRTGFNLQEEPVFYISIL 551 Query: 553 ARDGGVPSLSDTTDVEISVVDVNDN 577 D G+PSL+ T + I V D D+ Sbjct: 552 IADNGIPSLTSTNTLTIHVCDCGDS 576 Score = 156 bits (378), Expect = 9e-36 Identities = 124/427 (29%), Positives = 201/427 (47%), Gaps = 41/427 (9%) Query: 391 TDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD-SGG 448 +D D +N Y++ G F I + G I Q LD ++ Y+L D + G Sbjct: 68 SDLDNGNNSFQYKLLGAGAGSTFIIDERTGD--IYAIQKLDREERSLYILRAQVIDIATG 125 Query: 449 RS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD---VGINAQ 503 R+ + I ++D N+ P F + PY A V E +P GT V+ V+A+D+D G NA+ Sbjct: 126 RAVEPESEFVIKVSDINDNEPKFLDEPYEAIVPEMSPEGTLVIQVTASDADDPSSGNNAR 185 Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD--GGVPSL 561 + YSL F + P TG I + +DRE Y + + A+D G +L Sbjct: 186 LLYSL---------LQGQPYFSVEPTTGVIRISSKMDRELQDEYWVIIQAKDMIGQPGAL 236 Query: 562 SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD 621 S TT V I + DVNDN+P+FK+ LY + E A GTS+ + A D D+G N + Y ++ Sbjct: 237 SGTTSVLIKLSDVNDNKPIFKESLYRLTVSESAPTGTSIGTIMAYDNDIGENAEMDYSIE 296 Query: 622 PKDREEGSFVI--DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ-------SSTVI 672 D + + + G++ K +D E + ++A + P Q +ST Sbjct: 297 EDDSQTFDIITNHETQEGIVILKKKVDFEHQNHYGIRAKVKNHHVPEQLMKYHTEASTTF 356 Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD-- 730 + I++ED+ D PP+F F + E +P G+ +G + A DPD + + YSI Sbjct: 357 IKIQVEDV-DEPPLFLLPYYVFEVFEETPQGSFVGVVSATDPD-NRKSPIRYSITRSKVF 414 Query: 731 DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDN 790 + N T S E+ +L + +KY + + +S PL+ + V ++ND+ Sbjct: 415 NINDNGTITTSNSLDREISAWYNLSI-TATEKYN-IEQISSIPLY------VQVLNINDH 466 Query: 791 APVMKDF 797 AP + Sbjct: 467 APEFSQY 473 Score = 147 bits (355), Expect = 6e-33 Identities = 129/461 (27%), Positives = 210/461 (45%), Gaps = 43/461 (9%) Query: 311 IDPRSGWVYTSGQLDRETQAKY----QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXF 366 ID R+G +Y +LDRE ++ Y Q++ AT P S F Sbjct: 92 IDERTGDIYAIQKLDREERSLYILRAQVIDIATGRAVEPESEFVIKVSDINDNEPK---F 148 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDN-----RLHYEITGGNTRGRFSITSQNGRG 421 + YE + E P GT V+ +TA+DAD+ + RL Y + G FS+ G Sbjct: 149 LDEPYEAIVPEMSPEGTLVIQVTASDADDPSSGNNARLLYSLLQGQPY--FSVEPTTG-- 204 Query: 422 LITVAQPLDFKQERRYVLTVSATDS----GGRSDTAMVQINITDANNYAPVFENAPYTAS 477 +I ++ +D + + Y + + A D G S T V I ++D N+ P+F+ + Y + Sbjct: 205 VIRISSKMDRELQDEYWVIIQAKDMIGQPGALSGTTSVLIKLSDVNDNKPIFKESLYRLT 264 Query: 478 VFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN--EAVAHHDQQFVINPQTGAITT 535 V E AP GT++ + A D+D+G NA++ YS+ + S + + +H+ Q G + Sbjct: 265 VSESAPTGTSIGTIMAYDNDIGENAEMDYSIEEDDSQTFDIITNHETQ------EGIVIL 318 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSL-------SDTTDVEISVVDVNDNEPVFKQQLYTA 588 K +D E + Y + ++ VP + TT ++I V DV D P+F Y Sbjct: 319 KKKVDFEHQNHYGIRAKVKNHHVPEQLMKYHTEASTTFIKIQVEDV-DEPPLFLLPYYVF 377 Query: 589 NIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE 648 + E+ G+ V V ATD D I Y + R + + D +G I T+ +LDRE Sbjct: 378 EVFEETPQGSFVGVVSATDPD-NRKSPIRYSIT---RSKVFNIND--NGTITTSNSLDRE 431 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 A ++L A + Q S++ +++++ +IND P F S Y+ EN+ G I Sbjct: 432 ISAWYNLSITATEKYNIEQISSIPLYVQVLNINDHAPEF-SQYYETYVCENAGSGQVIQT 490 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV 749 I A D DE Y +D+N+ S D ++ Sbjct: 491 ISAVDRDESIEEHHFYFNLSVEDTNNSSFTIIDNQDNTAVI 531 Score = 110 bits (265), Expect = 5e-22 Identities = 119/476 (25%), Positives = 207/476 (43%), Gaps = 58/476 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVTA 67 I V D ND+ P F + YEA V E + GT V+ + A+D D G NA + Y++ Sbjct: 136 IKVSDINDNEPKFLDEPYEAIVPEMSPEGTLVIQVTASDADDPSSGNNARLLYSL----- 190 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 Q F ++ +G + + +DRE Y V+++A D Sbjct: 191 ----------------LQGQPYFSVEPTTGVIRISSKMDRELQDEYWVIIQAKDMIGQ-P 233 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 LS T ++ + + D NDN P F E Y ++V E S I I A D D+G N+ + Sbjct: 234 GALSGTTSVLIKLSDVNDNKPIFKESLYRLTVSE--SAPTGTSIGTIMAYDNDIGENAEM 291 Query: 188 RYAIIGGNTQMQFSI----DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSP-------S 236 Y+I ++Q F I ++ G V L K +D+E Y + + ++ P + Sbjct: 292 DYSIEEDDSQ-TFDIITNHETQEGIVILKKKVDFEHQNHYGIRAKVKNHHVPEQLMKYHT 350 Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 ++TT + I + DV D P F + V E P G + V A D D + + Y++ Sbjct: 351 EASTTFIKIQVEDV-DEPPLFLLPYYVFEVFEETPQGSFVGVVSATDPDNR-KSPIRYSI 408 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 T + N++ +G + TS LDRE A Y L +TAT+ + + ++ Sbjct: 409 T-RSKVFNIN-------DNGTITTSNSLDREISAWYNLSITATEKYNIEQISSIPLYVQV 460 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNT-RGRF 412 F YE + E+ G + T++A D D E++ ++ ++ +T F Sbjct: 461 LNINDHAPEFSQ-YYETYVCENAGSGQVIQTISAVDRDESIEEHHFYFNLSVEDTNNSSF 519 Query: 413 SI--TSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANN 464 +I N ++T + ++E + +++ D+G + T + I++ D + Sbjct: 520 TIIDNQDNTAVILTNRTGFNLQEEPVFYISILIADNGIPSLTSTNTLTIHVCDCGD 575 >UniRef50_UPI0000D57279 Cluster: PREDICTED: similar to CG14900-PA; n=1; Tribolium castaneum|Rep: PREDICTED: similar to CG14900-PA - Tribolium castaneum Length = 1761 Score = 170 bits (413), Expect = 5e-40 Identities = 212/833 (25%), Positives = 354/833 (42%), Gaps = 97/833 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-LKATDQDIGK--NAEVEYTIELVTA 67 + V D NDH+PVF Y+ +V E G T+ ++A+D+D N++V+Y I Sbjct: 123 VYVEDVNDHAPVFVGAPYQLAVDELTPVGLTIFRGIRASDRDKPNTPNSDVQYAI----- 177 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGA-LLTRASLDREKVAR-YTVLVKATDQASP 125 + F +D A L+ + LD + R + + + A+D+ P Sbjct: 178 --------------ISGNERGKFALDSSQQAFLILKRPLDYDTGDREFLLTIAASDRGIP 223 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIA------KIKATDA 179 S+ TI + + D++D P+F++ Y ++E +T + I A D Sbjct: 224 PR---STNTTIRITVNDNDDLSPKFTKGVYRTRINEFYPITGERIHKLLTFDPAIHAFDQ 280 Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRS-----YRLVIRAQDGGS 234 D+ ++ IRY II GN + FS+D ++G + + + +D + RS + L I+A + Sbjct: 281 DIAIDAPIRYDIIAGNERHIFSLDHVNGSLFIEREIDIDSERSLPGNTFVLQIQASQVDN 340 Query: 235 PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294 P+++ ++ + I D+NDN P F + S+ EN+P G+S++++ A D D+G NAE +Y Sbjct: 341 PAKTGVARVEVEIMDLNDNLPEFEVDFYNISIVENLPNGFSVLQIIAVDQDQGDNAEFSY 400 Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDG-----GDPPRS 347 + +D TG T+D R+GW+ Q LDRE ++ ++ V A + + Sbjct: 401 QL--EDNTG----AFTLDSRTGWLTVRDQSVLDREKRSTLRMQVYAKEKVPSVVSSKLGA 454 Query: 348 ATATXXXXXXXXXXXXXXFMPGQ-YEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEI- 403 + F+P Y D G V + A D D + + Y I Sbjct: 455 SAVNIEVTLLDANDNNPTFIPNNLYNFITNSDLKIGDVVGQIHAIDPDLGRNGIVTYSIQ 514 Query: 404 TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD-----SGGRSDTAMVQIN 458 N F + ++G+ I+V Q + R++L V A+D S RS A+V I Sbjct: 515 KAPNNTVPFKVDPKSGK--ISVNQKV--VTPGRHLLFVEASDQPLNPSERRSSLAVVTIE 570 Query: 459 ITDANNYA-----PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513 + P F APY V + +GT+V + +DV I Y L Sbjct: 571 VQQQTGKGTVKGLPDFIGAPYEFWVGGNVGVGTSVGQIRV--ADVPDRRTIIYDLLHSY- 627 Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVD 573 H F + ++G IT L+ Y + +L T+V I VVD Sbjct: 628 -----HEGVPFAVEERSGTITVVDNLENYNRQNYEFEAVVTNEKEMTL--VTNVTIHVVD 680 Query: 574 VNDNEPVFKQQLYTANI---MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSF 630 D + + + TA I +++ + ++G +A+ +G + + KD E Sbjct: 681 PKDEKTIL-MKAGTAPIEFHVKENAGNLLIGRLGFKNAN--SSGLVFSIANQKDVTE--H 735 Query: 631 VIDPASGVIRTNKALDRESVATHDLKAVA-IDGGTPPQSSTVIVHIKIEDINDSPPVFES 689 + + G + T K LDRE+ + L +A G + V I ++D ND+ P FE Sbjct: 736 ISITSDGSLYTVKPLDRETRDVYRLTVLAEYSKGAITGTGIYQVTIHVDDENDNKPTFEH 795 Query: 690 DCLTFYISENSPIGTTIG---EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKA 746 ++EN GT + I D D G N +I G+ S F L+ G Sbjct: 796 SKYEGKVTENCISGTEVDLNYLIHVSDKDTGDNGQFGVTI-FGNGSEKFRLDRNTGK--- 851 Query: 747 ELVTMVD--LDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDF 797 T D LD E ++ L+++ + I+V D NDNAP F Sbjct: 852 IFFTSADSPLDREETGIFNLRLVAKDQGGLYDEAILIIMVEDENDNAPTFVQF 904 Score = 169 bits (412), Expect = 7e-40 Identities = 154/573 (26%), Positives = 254/573 (44%), Gaps = 63/573 (10%) Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR-VQAYDADEG-- 287 D G +++ + + + DVND+AP F + +Q +V E P+G +I R ++A D D+ Sbjct: 109 DDGEDIITSSLSVTVYVEDVNDHAPVFVGAPYQLAVDELTPVGLTIFRGIRASDRDKPNT 168 Query: 288 VNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET-QAKYQLLVTATDGGDPPR 346 N+++ Y + + G L + + ++ LD +T ++ L + A+D G PPR Sbjct: 169 PNSDVQYAIISGNERGKFALDSS---QQAFLILKRPLDYDTGDREFLLTIAASDRGIPPR 225 Query: 347 SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP----------PGTPVVTLTATDADED 396 S T F G Y + E P P + D D Sbjct: 226 STNTTIRITVNDNDDLSPKFTKGVYRTRINEFYPITGERIHKLLTFDPAIHAFDQDIAID 285 Query: 397 NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR-----YVLTVSAT--DSGGR 449 + Y+I GN R FS+ NG + + + +D ER +VL + A+ D+ + Sbjct: 286 APIRYDIIAGNERHIFSLDHVNGS--LFIEREIDIDSERSLPGNTFVLQIQASQVDNPAK 343 Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509 + A V++ I D N+ P FE Y S+ E+ P G +VL + A D D G NA+ +Y L Sbjct: 344 TGVARVEVEIMDLNDNLPEFEVDFYNISIVENLPNGFSVLQIIAVDQDQGDNAEFSYQLE 403 Query: 510 SEISNEAVAHHDQQFVINPQTGAITTN--KLLDRETMSGYLLTVTARDGGVPSL------ 561 F ++ +TG +T +LDRE S + V A++ VPS+ Sbjct: 404 DNTG---------AFTLDSRTGWLTVRDQSVLDREKRSTLRMQVYAKEK-VPSVVSSKLG 453 Query: 562 SDTTDVEISVVDVNDNEPVF-KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620 + ++E++++D NDN P F LY D +G V Q+ A D D+G NG + Y + Sbjct: 454 ASAVNIEVTLLDANDNNPTFIPNNLYNFITNSDLKIGDVVGQIHAIDPDLGRNGIVTYSI 513 Query: 621 DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPP---QSSTVIVHIKI 677 F +DP SG I N+ + + H L A D P +SS +V I++ Sbjct: 514 QKAPNNTVPFKVDPKSGKISVNQKV--VTPGRHLLFVEASDQPLNPSERRSSLAVVTIEV 571 Query: 678 EDINDSP-----PVFESDCLTFYISENSPIGTTIGEIRAHD-PDEGPNAVVHYSIKGGDD 731 + P F F++ N +GT++G+IR D PD +++ + + Sbjct: 572 QQQTGKGTVKGLPDFIGAPYEFWVGGNVGVGTSVGQIRVADVPDR--RTIIYDLLHSYHE 629 Query: 732 SNSFSLETRQGSDKAELVTMVDLDYESPRKKYE 764 F++E R G+ +T+VD R+ YE Sbjct: 630 GVPFAVEERSGT-----ITVVDNLENYNRQNYE 657 Score = 149 bits (362), Expect = 8e-34 Identities = 181/767 (23%), Positives = 328/767 (42%), Gaps = 72/767 (9%) Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV--GANS 185 D ++S+ ++ V + D ND+ P F Y ++VDE ++ + I+A+D D NS Sbjct: 113 DIITSSLSVTVYVEDVNDHAPVFVGAPYQLAVDE-LTPVGLTIFRGIRASDRDKPNTPNS 171 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVK-TLDYEQ-VRSYRLVIRAQDGGSPSRSNTTQL 243 ++YAII GN + +F++DS ++K LDY+ R + L I A D G P RS T + Sbjct: 172 DVQYAIISGNERGKFALDSSQQAFLILKRPLDYDTGDREFLLTIAASDRGIPPRSTNTTI 231 Query: 244 LINIRDVNDNAPRFYTSLFQESVSENVPI-GYSIVR-------VQAYDADEGVNAELTYT 295 I + D +D +P+F +++ ++E PI G I + + A+D D ++A + Y Sbjct: 232 RITVNDNDDLSPKFTKGVYRTRINEFYPITGERIHKLLTFDPAIHAFDQDIAIDAPIRYD 291 Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAK-----YQLLVTATDGGDPPRSATA 350 + GN ++D +G ++ ++D +++ + L + A+ +P ++ A Sbjct: 292 I----IAGNERHIFSLDHVNGSLFIEREIDIDSERSLPGNTFVLQIQASQVDNPAKTGVA 347 Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG 410 F Y + + E+ P G V+ + A D D+ + + + G Sbjct: 348 RVEVEIMDLNDNLPEFEVDFYNISIVENLPNGFSVLQIIAVDQDQGDNAEFSYQLEDNTG 407 Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTV---------SATDSGGRSDTAMVQINITD 461 F++ S+ G +TV +E+R L + S S + +++ + D Sbjct: 408 AFTLDSRT--GWLTVRDQSVLDREKRSTLRMQVYAKEKVPSVVSSKLGASAVNIEVTLLD 465 Query: 462 ANNYAPVF-ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520 AN+ P F N Y D IG V + A D D+G N +TYS+ +N Sbjct: 466 ANDNNPTFIPNNLYNFITNSDLKIGDVVGQIHAIDPDLGRNGIVTYSIQKAPNNTV---- 521 Query: 521 DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE-- 578 F ++P++G I+ N+ + T +LL V A D + + + + ++V Sbjct: 522 --PFKVDPKSGKISVNQKV--VTPGRHLLFVEASDQPLNPSERRSSLAVVTIEVQQQTGK 577 Query: 579 ------PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632 P F Y + + VGTSV Q+ ADV I Y+L E F + Sbjct: 578 GTVKGLPDFIGAPYEFWVGGNVGVGTSVGQIRV--ADVPDRRTIIYDLLHSYHEGVPFAV 635 Query: 633 DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDC- 691 + SG I L+ + ++ +AV + + V +H+ ++ ++ + ++ Sbjct: 636 EERSGTITVVDNLENYNRQNYEFEAVVTNEKEMTLVTNVTIHV-VDPKDEKTILMKAGTA 694 Query: 692 -LTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750 + F++ EN+ IG + + + ++ + +SI D T GS L T Sbjct: 695 PIEFHVKENAG-NLLIGRLGFKNAN---SSGLVFSIANQKDVTEHISITSDGS----LYT 746 Query: 751 MVDLDYESPRKKYELVIRA----ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKD 806 + LD E+ R Y L + A + +V I V D NDN P + + ++ Sbjct: 747 VKPLDRET-RDVYRLTVLAEYSKGAITGTGIYQVTIHVDDENDNKPTFEHSKYEGKVTEN 805 Query: 807 CF---PVGPFGRVPAYDADVTDKLQYRI-LSGNNANLILLNETTGSM 849 C V + D D D Q+ + + GN + L+ TG + Sbjct: 806 CISGTEVDLNYLIHVSDKDTGDNGQFGVTIFGNGSEKFRLDRNTGKI 852 Score = 144 bits (349), Expect = 3e-32 Identities = 170/664 (25%), Positives = 280/664 (42%), Gaps = 82/664 (12%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ ++D ND+ P FE+ Y S+ E +G +VL + A DQD G NAE Y +E T Sbjct: 350 EVEIMDLNDNLPEFEVDFYNISIVENLPNGFSVLQIIAVDQDQGDNAEFSYQLEDNTG-- 407 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR--ASLDREKVARYTVLVKATDQA-SPV 126 F +D R+G L R + LDREK + + V A ++ S V Sbjct: 408 -------------------AFTLDSRTGWLTVRDQSVLDREKRSTLRMQVYAKEKVPSVV 448 Query: 127 SDRLSSTA-TIHVNIIDDNDNYPQF-SEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184 S +L ++A I V ++D NDN P F Y + D+ + D V+ +I A D D+G N Sbjct: 449 SSKLGASAVNIEVTLLDANDNNPTFIPNNLYNFITNSDLKIGD--VVGQIHAIDPDLGRN 506 Query: 185 SAIRYAI-IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD---GGSPSRSNT 240 + Y+I N + F +D SG +S+ + + + L + A D S RS+ Sbjct: 507 GIVTYSIQKAPNNTVPFKVDPKSGKISVNQKV--VTPGRHLLFVEASDQPLNPSERRSSL 564 Query: 241 TQLLINIRDVNDNA-----PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295 + I ++ P F + ++ V NV +G S+ +++ D + + Y Sbjct: 565 AVVTIEVQQQTGKGTVKGLPDFIGAPYEFWVGGNVGVGTSVGQIRVADVPD--RRTIIYD 622 Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355 + + G +P ++ RSG + L+ + Y+ T+ + T Sbjct: 623 LLHSYHEG---VPFAVEERSGTITVVDNLENYNRQNYEFEAVVTNEKE-MTLVTNVTIHV 678 Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITG-GNTRGRFSI 414 G +E E G ++ + L + I + SI Sbjct: 679 VDPKDEKTILMKAGTAPIEFHVKENAGNLLIGRLGFKNANSSGLVFSIANQKDVTEHISI 738 Query: 415 TSQNGRGLITVAQPLDFKQERRYVLTVSATDS-GGRSDTAMVQ--INITDANNYAPVFEN 471 TS G + +PLD + Y LTV A S G + T + Q I++ D N+ P FE+ Sbjct: 739 TSD---GSLYTVKPLDRETRDVYRLTVLAEYSKGAITGTGIYQVTIHVDDENDNKPTFEH 795 Query: 472 APYTASVFEDAPIGTTV---LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528 + Y V E+ GT V ++ +D D G N Q ++ + ++F ++ Sbjct: 796 SKYEGKVTENCISGTEVDLNYLIHVSDKDTGDNGQFGVTI--------FGNGSEKFRLDR 847 Query: 529 QTGAI---TTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585 TG I + + LDRE + L + A+D G L D + I V D NDN P F Q + Sbjct: 848 NTGKIFFTSADSPLDREETGIFNLRLVAKDQG--GLYDEAILIIMVEDENDNAPTFVQFI 905 Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645 + ED +G V + +G H+E ++ +G++V+ PA R KA Sbjct: 906 ----VYED--IGAEVEEYDKLGNRIG-----HFE-QLENSTKGTYVLTPA--YTRAKKAK 951 Query: 646 DRES 649 + S Sbjct: 952 SKMS 955 Score = 135 bits (326), Expect = 2e-29 Identities = 132/438 (30%), Positives = 195/438 (44%), Gaps = 73/438 (16%) Query: 373 VELAEDEPPGTPVVTLTATDAD-EDNR-LHYE------ITGGNTRGRFSITS----QNGR 420 V L ED GTPV+ L A D D DN + YE I + F +T Sbjct: 958 VVLKEDVGVGTPVIKLVAEDRDFGDNAVVKYEMVSETYIPNEYSAEPFHLTQYFMVHATN 1017 Query: 421 GLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFE 480 G I+V++ L + E R L +SA+D GG D V++ I D N++ PVF + Y E Sbjct: 1018 GEISVSRTLPPESEFR--LNISASDKGGLKDHISVRLTIEDVNDHPPVFSKSWYNFDAEE 1075 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 + + V A D D G NA ITY + + F I PQ G +T + +LD Sbjct: 1076 ASYSRNIIGRVEAIDGDFGPNANITYKIQEK-------DPKLPFAITPQGGVLTIDGVLD 1128 Query: 541 RETMSGYLLTVTARDGGV--PSLSDTTDVEISVVDVNDNEPVF----------------- 581 RET Y V A+D SLS +VE++V+DVNDN P F Sbjct: 1129 RETKDKYNFVVVAKDNPTKGESLSSFVNVEVNVLDVNDNPPSFYGYDDLLPNPESNTYSN 1188 Query: 582 --KQQ---LYTANIMEDALVGTSVSQVGATDADV--GLNGRIHYELDPKDREEGSFVIDP 634 Q+ +Y A + E++ +GT V+++ A D+D NG + +++ K + F ID Sbjct: 1189 HNYQEDIPVYYATVAENSPIGTPVTRIFANDSDFTGNGNGLLLFDIPYKKNRQNLFTIDS 1248 Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND-----SPPVFES 689 G++ T LD E+ H++ VA D G+P SST ++ + + D+ + PVF Sbjct: 1249 KEGIVTTIGKLDFENQNMHNITIVASDLGSPSLSSTALLVVTVIDVPEDLQSMEHPVFAH 1308 Query: 690 DCLTFYISENSPI-------------------GTTIGEIRAHDPDEGPNAVVHYSIKGGD 730 + EN P+ G I ++A DPD G N V Y I G Sbjct: 1309 RYYEVEVEENVPVPLKVLTLNVTESYSTTASYGHHIVRLQAKDPDLGLNGEVRYQILGRA 1368 Query: 731 D--SNSFSLETRQGSDKA 746 D + F+++ G +A Sbjct: 1369 DEAARRFTIDPITGQVRA 1386 Score = 123 bits (296), Expect = 8e-26 Identities = 104/350 (29%), Positives = 169/350 (48%), Gaps = 43/350 (12%) Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSE--ISNEAVA---HHDQQFVINPQTGAIT 534 ED +GT V+ + A D D G NA + Y + SE I NE A H Q F+++ G I+ Sbjct: 962 EDVGVGTPVIKLVAEDRDFGDNAVVKYEMVSETYIPNEYSAEPFHLTQYFMVHATNGEIS 1021 Query: 535 TNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDA 594 ++ L E S + L ++A D G L D V +++ DVND+ PVF + Y + E + Sbjct: 1022 VSRTLPPE--SEFRLNISASDKG--GLKDHISVRLTIEDVNDHPPVFSKSWYNFDAEEAS 1077 Query: 595 LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHD 654 + +V A D D G N I Y++ KD + F I P GV+ + LDRE+ ++ Sbjct: 1078 YSRNIIGRVEAIDGDFGPNANITYKIQEKD-PKLPFAITPQGGVLTIDGVLDRETKDKYN 1136 Query: 655 LKAVAIDGGTPPQ--SSTVIVHIKIEDINDSPPVF--------------------ESDCL 692 VA D T + SS V V + + D+ND+PP F + D Sbjct: 1137 FVVVAKDNPTKGESLSSFVNVEVNVLDVNDNPPSFYGYDDLLPNPESNTYSNHNYQEDIP 1196 Query: 693 TFY--ISENSPIGTTIGEIRAHDPD--EGPNAVVHYSIK-GGDDSNSFSLETRQGSDKAE 747 +Y ++ENSPIGT + I A+D D N ++ + I + N F++++++G Sbjct: 1197 VYYATVAENSPIGTPVTRIFANDSDFTGNGNGLLLFDIPYKKNRQNLFTIDSKEGI---- 1252 Query: 748 LVTMVDLDYESPRKKYELVIRA--ASPPLWNDVRVEILVTDVNDNAPVMK 795 + T+ LD+E+ ++ + SP L + + + V DV ++ M+ Sbjct: 1253 VTTIGKLDFENQNMHNITIVASDLGSPSLSSTALLVVTVIDVPEDLQSME 1302 Score = 118 bits (284), Expect = 2e-24 Identities = 110/391 (28%), Positives = 175/391 (44%), Gaps = 46/391 (11%) Query: 32 VREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFR 91 ++E GT V+ L A D+D G NA V+Y E+V+ +T P + + F Sbjct: 960 LKEDVGVGTPVIKLVAEDRDFGDNAVVKY--EMVS-ETYIPNE----YSAEPFHLTQYFM 1012 Query: 92 IDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFS 151 + +G + +L E + + + + A+D+ + D +S TI D ND+ P FS Sbjct: 1013 VHATNGEISVSRTLPPE--SEFRLNISASDKGG-LKDHISVRLTIE----DVNDHPPVFS 1065 Query: 152 EKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSL 211 + Y +E S + N +I +++A D D G N+ I Y I + ++ F+I G +++ Sbjct: 1066 KSWYNFDAEE-ASYSRN-IIGRVEAIDGDFGPNANITYKIQEKDPKLPFAITPQGGVLTI 1123 Query: 212 VKTLDYEQVRSYRLVIRAQDGGS--PSRSNTTQLLINIRDVNDNAPRFY----------- 258 LD E Y V+ A+D + S S+ + +N+ DVNDN P FY Sbjct: 1124 DGVLDRETKDKYNFVVVAKDNPTKGESLSSFVNVEVNVLDVNDNPPSFYGYDDLLPNPES 1183 Query: 259 -----------TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 ++ +V+EN PIG + R+ A D+D N + D Y N Sbjct: 1184 NTYSNHNYQEDIPVYYATVAENSPIGTPVTRIFANDSDFTGNGN-GLLLFDIPYKKNRQN 1242 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX-----XXXXXXX 362 TID + G V T G+LD E Q + + + A+D G P S+TA Sbjct: 1243 LFTIDSKEGIVTTIGKLDFENQNMHNITIVASDLGSPSLSSTALLVVTVIDVPEDLQSME 1302 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDA 393 F YEVE+ E+ P V+TL T++ Sbjct: 1303 HPVFAHRYYEVEVEENVPVPLKVLTLNVTES 1333 Score = 111 bits (266), Expect = 4e-22 Identities = 115/393 (29%), Positives = 167/393 (42%), Gaps = 71/393 (18%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 I ++ + D NDH PVF Y E + S + ++A D D G NA + Y I+ Sbjct: 1048 ISVRLTIEDVNDHPPVFSKSWYNFDAEEASYSRNIIGRVEAIDGDFGPNANITYKIQ--E 1105 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 D P F I + G L LDRE +Y +V A D + Sbjct: 1106 KDPKLP-----------------FAITPQGGVLTIDGVLDRETKDKYNFVVVAKDNPTK- 1147 Query: 127 SDRLSSTATIHVNIIDDNDNYPQF----------SEKTYTV-SVDEDISV------TDNP 169 + LSS + VN++D NDN P F TY+ + EDI V ++P Sbjct: 1148 GESLSSFVNVEVNVLDVNDNPPSFYGYDDLLPNPESNTYSNHNYQEDIPVYYATVAENSP 1207 Query: 170 V---IAKIKATDADV--GANSAIRYAI-IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY 223 + + +I A D+D N + + I N Q F+IDS G V+ + LD+E + Sbjct: 1208 IGTPVTRIFANDSDFTGNGNGLLLFDIPYKKNRQNLFTIDSKEGIVTTIGKLDFENQNMH 1267 Query: 224 RLVIRAQDGGSPSRSNTTQLLINIRDVNDNA-----PRFYTSLFQESVSENVPI------ 272 + I A D GSPS S+T L++ + DV ++ P F ++ V ENVP+ Sbjct: 1268 NITIVASDLGSPSLSSTALLVVTVIDVPEDLQSMEHPVFAHRYYEVEVEENVPVPLKVLT 1327 Query: 273 -------------GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319 G+ IVR+QA D D G+N E+ Y + + TIDP +G V Sbjct: 1328 LNVTESYSTTASYGHHIVRLQAKDPDLGLNGEVRYQILGR--ADEAARRFTIDPITGQVR 1385 Query: 320 TSGQLDRETQAKYQLLVTATD--GGDPPRSATA 350 R+ Y V ATD G D +S+ A Sbjct: 1386 AIANFARDAGKVYGFDVKATDRRGADDGKSSIA 1418 Score = 94.7 bits (225), Expect = 3e-17 Identities = 122/477 (25%), Positives = 201/477 (42%), Gaps = 73/477 (15%) Query: 266 VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN--------VDLPITIDPRSGW 317 + E+V +G ++++ A D D G NA + Y M + Y N + + +G Sbjct: 960 LKEDVGVGTPVIKLVAEDRDFGDNAVVKYEMVSETYIPNEYSAEPFHLTQYFMVHATNGE 1019 Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAE 377 + S L E++ ++L ++A+D G + F Y + E Sbjct: 1020 ISVSRTLPPESE--FRLNISASDKGGLKDHISVRLTIEDVNDHPPV--FSKSWYNFDAEE 1075 Query: 378 DEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435 + + A D D + + Y+I + + F+IT Q G ++T+ LD + + Sbjct: 1076 ASYSRNIIGRVEAIDGDFGPNANITYKIQEKDPKLPFAITPQGG--VLTIDGVLDRETKD 1133 Query: 436 RYVLTVSATDSGGRSDTAM----VQINITDANNYAPVF---------------------E 470 +Y V A D+ + ++ V++N+ D N+ P F E Sbjct: 1134 KYNFVVVAKDNPTKGESLSSFVNVEVNVLDVNDNPPSFYGYDDLLPNPESNTYSNHNYQE 1193 Query: 471 NAP-YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQ 529 + P Y A+V E++PIGT V + A DSD N L +I + + F I+ + Sbjct: 1194 DIPVYYATVAENSPIGTPVTRIFANDSDFTGNGNGL--LLFDIPYKK--NRQNLFTIDSK 1249 Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN-----EPVFKQQ 584 G +TT LD E + + +T+ A D G PSLS T + ++V+DV ++ PVF + Sbjct: 1250 EGIVTTIGKLDFENQNMHNITIVASDLGSPSLSSTALLVVTVIDVPEDLQSMEHPVFAHR 1309 Query: 585 LY---------------TANIMED----ALVGTSVSQVGATDADVGLNGRIHYE-LDPKD 624 Y T N+ E A G + ++ A D D+GLNG + Y+ L D Sbjct: 1310 YYEVEVEENVPVPLKVLTLNVTESYSTTASYGHHIVRLQAKDPDLGLNGEVRYQILGRAD 1369 Query: 625 REEGSFVIDPASGVIR--TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679 F IDP +G +R N A D V D+KA G +SS V + + D Sbjct: 1370 EAARRFTIDPITGQVRAIANFARDAGKVYGFDVKATDRRGADDGKSSIANVFVYVLD 1426 Score = 92.3 bits (219), Expect = 2e-16 Identities = 89/334 (26%), Positives = 148/334 (44%), Gaps = 23/334 (6%) Query: 555 DGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ-VGATDADVGL- 612 D G ++ + V + V DVND+ PVF Y + E VG ++ + + A+D D Sbjct: 109 DDGEDIITSSLSVTVYVEDVNDHAPVFVGAPYQLAVDELTPVGLTIFRGIRASDRDKPNT 168 Query: 613 -NGRIHYELDPKDREEGSFVIDPAS-GVIRTNKALDRESVATHDLKAVAI-DGGTPPQSS 669 N + Y + E G F +D + + + LD ++ L +A D G PP+S+ Sbjct: 169 PNSDVQYAII-SGNERGKFALDSSQQAFLILKRPLDYDTGDREFLLTIAASDRGIPPRST 227 Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPI-GTTIGEIRAHDP-------DEGPNAV 721 + I + D +D P F I+E PI G I ++ DP D +A Sbjct: 228 NTTIRITVNDNDDLSPKFTKGVYRTRINEFYPITGERIHKLLTFDPAIHAFDQDIAIDAP 287 Query: 722 VHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDV 778 + Y I G++ + FSL+ GS E +D + P + L I+A+ +P Sbjct: 288 IRYDIIAGNERHIFSLDHVNGSLFIEREIDIDSERSLPGNTFVLQIQASQVDNPAKTGVA 347 Query: 779 RVEILVTDVNDNAPVMKDFQIIFNNYK--DCFPVG-PFGRVPAYDADVTDKLQYRILSGN 835 RVE+ + D+NDN P +F++ F N + P G ++ A D D D ++ + Sbjct: 348 RVEVEIMDLNDNLP---EFEVDFYNISIVENLPNGFSVLQIIAVDQDQGDNAEFSYQLED 404 Query: 836 NANLILLNETTGSMTLSPQLNTNVPKLATMEVSV 869 N L+ TG +T+ Q + K +T+ + V Sbjct: 405 NTGAFTLDSRTGWLTVRDQSVLDREKRSTLRMQV 438 Score = 83.4 bits (197), Expect = 8e-14 Identities = 66/202 (32%), Positives = 97/202 (48%), Gaps = 22/202 (10%) Query: 151 SEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGG------------NTQM 198 S+ + V + ED+ V PVI K+ A D D G N+ ++Y ++ + Sbjct: 952 SKMSPLVVLKEDVGV-GTPVI-KLVAEDRDFGDNAVVKYEMVSETYIPNEYSAEPFHLTQ 1009 Query: 199 QFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFY 258 F + + +G++S+ +TL E +RL I A D G + +L I DVND+ P F Sbjct: 1010 YFMVHATNGEISVSRTLPPES--EFRLNISASDKGGLKDHISVRL--TIEDVNDHPPVFS 1065 Query: 259 TSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV 318 S + E I RV+A D D G NA +TY + +KD LP I P+ G + Sbjct: 1066 KSWYNFDAEEASYSRNIIGRVEAIDGDFGPNANITYKIQEKD----PKLPFAITPQGGVL 1121 Query: 319 YTSGQLDRETQAKYQLLVTATD 340 G LDRET+ KY +V A D Sbjct: 1122 TIDGVLDRETKDKYNFVVVAKD 1143 Score = 78.2 bits (184), Expect = 3e-12 Identities = 74/232 (31%), Positives = 103/232 (44%), Gaps = 29/232 (12%) Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP-----------ASGV 638 + ED VGT V ++ A D D G N + YE+ + + +P +G Sbjct: 960 LKEDVGVGTPVIKLVAEDRDFGDNAVVKYEMVSETYIPNEYSAEPFHLTQYFMVHATNGE 1019 Query: 639 IRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698 I ++ L ES ++ A + GG S V + IED+ND PPVF F E Sbjct: 1020 ISVSRTLPPESEFRLNISA-SDKGGLKDHIS---VRLTIEDVNDHPPVFSKSWYNFDAEE 1075 Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD--LDY 756 S IG + A D D GPNA + Y I+ D F++ T QG V +D LD Sbjct: 1076 ASYSRNIIGRVEAIDGDFGPNANITYKIQEKDPKLPFAI-TPQGG-----VLTIDGVLDR 1129 Query: 757 ESPRKKYELVIRAASPP-----LWNDVRVEILVTDVNDNAPVMKDFQIIFNN 803 E+ + KY V+ A P L + V VE+ V DVNDN P + + N Sbjct: 1130 ET-KDKYNFVVVAKDNPTKGESLSSFVNVEVNVLDVNDNPPSFYGYDDLLPN 1180 Score = 64.1 bits (149), Expect = 5e-08 Identities = 66/278 (23%), Positives = 121/278 (43%), Gaps = 41/278 (14%) Query: 7 IHQQINVLDCNDHSPVFE-----MQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYT 61 ++ ++NVLD ND+ P F + E++ + + AT + +N+ + Sbjct: 1155 VNVEVNVLDVNDNPPSFYGYDDLLPNPESNTYSNHNYQEDIPVYYAT---VAENSPIGTP 1211 Query: 62 IELVTAD----TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLV 117 + + A+ T N Q++F ID + G + T LD E + + + Sbjct: 1212 VTRIFANDSDFTGNGNGLLLFDIPYKKNRQNLFTIDSKEGIVTTIGKLDFENQNMHNITI 1271 Query: 118 KATDQASPVSDRLSSTATIHVNIIDDNDN-----YPQFSEKTYTVSVDEDISV-----TD 167 A+D SP LSSTA + V +ID ++ +P F+ + Y V V+E++ V T Sbjct: 1272 VASDLGSP---SLSSTALLVVTVIDVPEDLQSMEHPVFAHRYYEVEVEENVPVPLKVLTL 1328 Query: 168 NPV------------IAKIKATDADVGANSAIRYAIIG--GNTQMQFSIDSLSGDVSLVK 213 N I +++A D D+G N +RY I+G +F+ID ++G V + Sbjct: 1329 NVTESYSTTASYGHHIVRLQAKDPDLGLNGEVRYQILGRADEAARRFTIDPITGQVRAIA 1388 Query: 214 TLDYEQVRSYRLVIRAQD--GGSPSRSNTTQLLINIRD 249 + + Y ++A D G +S+ + + + D Sbjct: 1389 NFARDAGKVYGFDVKATDRRGADDGKSSIANVFVYVLD 1426 Score = 37.5 bits (83), Expect = 5.3 Identities = 36/126 (28%), Positives = 50/126 (39%), Gaps = 5/126 (3%) Query: 21 PVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT---LNPEDAXX 77 PVF + YE V E VLTL T+ + + + L D LN E Sbjct: 1304 PVFAHRYYEVEVEENVPVPLKVLTLNVTESYSTTASYGHHIVRLQAKDPDLGLNGEVRYQ 1363 Query: 78 XXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIH 137 + F ID +G + A+ R+ Y VKATD+ D SS A + Sbjct: 1364 ILGRADEAARR-FTIDPITGQVRAIANFARDAGKVYGFDVKATDRRG-ADDGKSSIANVF 1421 Query: 138 VNIIDD 143 V ++DD Sbjct: 1422 VYVLDD 1427 >UniRef50_Q7UY44 Cluster: Fat protein-possibly involved in cell-cell attachment; n=1; Pirellula sp.|Rep: Fat protein-possibly involved in cell-cell attachment - Rhodopirellula baltica Length = 2009 Score = 169 bits (412), Expect = 7e-40 Identities = 199/807 (24%), Positives = 329/807 (40%), Gaps = 65/807 (8%) Query: 37 SSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQD--VFRIDG 94 S+ + + D+ +NA++ T+ ++ N D+ D F IDG Sbjct: 905 STNVAPTAIAIDNNDVEENADIGTTVGTLSTTDANTMDSFVYTLVSGTGDTDNASFAIDG 964 Query: 95 RSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKT 154 + L+T ASLD E + Y+V +++TD LS+ T + + ND + Sbjct: 965 NN--LVTAASLDFETQSSYSVRIQSTDPFG-----LSTVETFTITATNVNDAPTAIAIDN 1017 Query: 155 YTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD-VSLVK 213 T++ D T + TD D A+ YA++ G+ + ++SG+ + Sbjct: 1018 STIAEDTASGTT----VGSFTTTDDD--ASDTFTYALVSGDGDTDNAAFTISGNNLVTAT 1071 Query: 214 TLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIG 273 T D+E SY IR Q S + L I + D N+ SL S+SE+ G Sbjct: 1072 TFDFETQSSYS--IRVQTTDSAGATFEQVLTITVTDTNEVPTAI--SLDNSSISEDAASG 1127 Query: 274 YSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD-LPITIDPRSGWVYTSGQLDRETQAKY 332 ++ DAD + TYT+ + G+ D TI G + T+ D +TQ+ Y Sbjct: 1128 TTVGAFSTTDAD--ASDTFTYTLVSGE--GDTDNAAFTIS--GGNLVTATTFDFDTQSSY 1181 Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392 + V D T ++E E GT V +L+ TD Sbjct: 1182 SIRVQTEDSAGATFEQVLTITITENEANQTPTAISIDNTDIE--EHATVGTTVGSLSTTD 1239 Query: 393 ADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT 452 A+ + Y + G + + +G L+T A DF+ + Y + V TDSGG + Sbjct: 1240 ANASDTFTYALVSGEGDTDNAAFTISGSNLVT-ATTFDFETQSSYSIRVQTTDSGGATFE 1298 Query: 453 AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512 ++ ++ITD+N+ AP A A++ ED GT V +S TD+D G TY+L + Sbjct: 1299 QILTLSITDSND-APT-SLAIDNATISEDVASGTVVGALSTTDADAG--DTFTYAL---V 1351 Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572 S E + F I+ + T D +T S Y + V + D +++ + I+ Sbjct: 1352 SGEGDT-DNAAFSIDGSN--LVTATTFDFDTQSSYSVRVQSTDSAGATITQVLTITIT-- 1406 Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVI 632 N + I ED GT V + TDAD G D + +F I Sbjct: 1407 --GTNAVPTAIAIDNDTIAEDVASGTVVGALSTTDADAGDTFTYALVSGDGDTDNAAFTI 1464 Query: 633 DPASGVIRTNKALDRESVATHDLKAVAID--GGTPPQSSTVIVHIKIEDINDSPPVFESD 690 D ++ V T D E+ ++ ++ D G T Q ++ I + D+N++P D Sbjct: 1465 DGSNLVTAT--TFDFETQDSYSVRVQTTDSAGATFEQ----VLTISVTDVNETPTAIAID 1518 Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVT 750 ++E+ GT +G + D D G Y++ GD + T GS+ LVT Sbjct: 1519 --NSSVAEDVASGTVVGALSTTDADAGDTFT--YALVSGDGDTDNASFTIDGSN---LVT 1571 Query: 751 MVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCF 808 D+E+ V S + + I +TDVN+ AP + ++ + Sbjct: 1572 ATTFDFETQDSYSVRVQTTDSDGATFEQTLTISITDVNE-APTAISISSSVVTEDSTSGT 1630 Query: 809 PVGPFGRVPAYDADVTDKLQYRILSGN 835 VG F D D +D Y +++G+ Sbjct: 1631 TVGSFSTT---DVDASDTFTYTLVAGD 1654 Score = 167 bits (406), Expect = 4e-39 Identities = 205/851 (24%), Positives = 336/851 (39%), Gaps = 78/851 (9%) Query: 30 ASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDV 89 +++ E +SGTTV + TD D A +T LV+ D + ++A Sbjct: 1018 STIAEDTASGTTVGSFTTTDDD----ASDTFTYALVSGDG-DTDNAA------------- 1059 Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F I G + L+T + D E + Y++ V+ TD A +++ + + + D N+ Sbjct: 1060 FTISGNN--LVTATTFDFETQSSYSIRVQTTDSAGATFEQV-----LTITVTDTNEVPTA 1112 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG-D 208 S ++S D T + TDAD A+ Y ++ G + ++SG + Sbjct: 1113 ISLDNSSISEDAASGTT----VGAFSTTDAD--ASDTFTYTLVSGEGDTDNAAFTISGGN 1166 Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268 + T D++ SY + ++ +D + + I + N S+ + E Sbjct: 1167 LVTATTFDFDTQSSYSIRVQTEDSAGATFEQVLTITITENEANQTPTAI--SIDNTDIEE 1224 Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328 + +G ++ + DA NA T+T G+ D S V T+ D ET Sbjct: 1225 HATVGTTVGSLSTTDA----NASDTFTYALVSGEGDTDNAAFTISGSNLV-TATTFDFET 1279 Query: 329 QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388 Q+ Y + V TD G T ++ED GT V L Sbjct: 1280 QSSYSIRVQTTDSGGATFEQILTLSITDSNDAPTSLAID----NATISEDVASGTVVGAL 1335 Query: 389 TATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG 448 + TDAD + Y + G + S +G L+T A DF + Y + V +TDS G Sbjct: 1336 STTDADAGDTFTYALVSGEGDTDNAAFSIDGSNLVT-ATTFDFDTQSSYSVRVQSTDSAG 1394 Query: 449 RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508 + T ++ I IT N A ++ ED GT V +S TD+D G TY+L Sbjct: 1395 ATITQVLTITITGTNAVPTAI--AIDNDTIAEDVASGTVVGALSTTDADAGDT--FTYAL 1450 Query: 509 SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568 S + A F I+ + T D ET Y + V D + + Sbjct: 1451 VSGDGDTDNA----AFTIDGSN--LVTATTFDFETQDSYSVRVQTTDSAGATFEQV--LT 1502 Query: 569 ISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG 628 ISV DVN+ + +++ ED GT V + TDAD G D + Sbjct: 1503 ISVTDVNETPTAIA--IDNSSVAEDVASGTVVGALSTTDADAGDTFTYALVSGDGDTDNA 1560 Query: 629 SFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFE 688 SF ID ++ V T + + + ++ DG T Q+ T I I D+N++P Sbjct: 1561 SFTIDGSNLVTATTFDFETQDSYSVRVQTTDSDGATFEQTLT----ISITDVNEAPTAIS 1616 Query: 689 SDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAEL 748 + ++E+S GTT+G D D Y++ GD + T G + L Sbjct: 1617 IS--SSVVTEDSTSGTTVGSFSTTDVDASDTFT--YTLVAGDGDTDNASFTIDGGN---L 1669 Query: 749 VTMVDLDYESPRKKYELVIRAASPP-LWNDVRVEILVTDVNDNAP--VMKDFQIIFNNYK 805 VT LD ++ + Y + +R+ + + I VT+ N +AP + D I N Sbjct: 1670 VTATTLDMDT-QSSYSIRVRSTDAGGSFVEQTFTITVTETN-SAPTAIALDDATIAENAA 1727 Query: 806 DCFPVGPFGRVPAYDADVTDKLQYRILSG-NNANLILLNETTGSMTLSPQLNTNVPKLAT 864 VG DADV D Y ++SG + + L G++ + + + Sbjct: 1728 IGTVVGALSTT---DADVADTFTYSLVSGVGDTDNALFAIDGGNLVTAATFDFETQSSYS 1784 Query: 865 MEVSVTDGVNE 875 + + +D V E Sbjct: 1785 VRIQSSDAVGE 1795 Score = 150 bits (364), Expect = 5e-34 Identities = 185/730 (25%), Positives = 301/730 (41%), Gaps = 71/730 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 +++ D ND + A++ E +SGT V L TD D G +T LV+ + Sbjct: 1303 LSITDSNDAPTSLAIDN--ATISEDVASGTVVGALSTTDADAGDT----FTYALVSGEG- 1355 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + ++A F IDG + L+T + D + + Y+V V++TD A Sbjct: 1356 DTDNAA-------------FSIDGSN--LVTATTFDFDTQSSYSVRVQSTDSAGA----- 1395 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + T + + I N + T++ D V V+ + TDAD G YA Sbjct: 1396 TITQVLTITITGTNAVPTAIAIDNDTIAED----VASGTVVGALSTTDADAG--DTFTYA 1449 Query: 191 IIGGNTQMQFSIDSLSG-DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 ++ G+ + ++ G ++ T D+E SY +R Q S + L I++ D Sbjct: 1450 LVSGDGDTDNAAFTIDGSNLVTATTFDFETQDSYS--VRVQTTDSAGATFEQVLTISVTD 1507 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD-LP 308 VN+ ++ SV+E+V G + + DAD G TY + D G+ D Sbjct: 1508 VNETPTAI--AIDNSSVAEDVASGTVVGALSTTDADAGDT--FTYALVSGD--GDTDNAS 1561 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMP 368 TID + + T+ D ETQ Y + V TD T T Sbjct: 1562 FTIDGSN--LVTATTFDFETQDSYSVRVQTTDSDGATFEQTLTISITDVNEAPTAISISS 1619 Query: 369 GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQP 428 + ED GT V + + TD D + Y + G+ + + +G L+T A Sbjct: 1620 SV----VTEDSTSGTTVGSFSTTDVDASDTFTYTLVAGDGDTDNASFTIDGGNLVT-ATT 1674 Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 LD + Y + V +TD+GG I +T+ N+ AP A A++ E+A IGT V Sbjct: 1675 LDMDTQSSYSIRVRSTDAGGSFVEQTFTITVTETNS-APT-AIALDDATIAENAAIGTVV 1732 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 +S TD+DV TYSL S + + + F I+ G + T D ET S Y Sbjct: 1733 GALSTTDADVA--DTFTYSLVSGVGDT----DNALFAID--GGNLVTAATFDFETQSSYS 1784 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 + + + D ++S + I+VVD+ND P + A I G V +GA D Sbjct: 1785 VRIQSSDAVGETVSQS--FVITVVDIND-APTGLTLPFPA-IASGQASGFLVGNLGAEDQ 1840 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 D G + D + F + G +RT +A D A + ++ D Sbjct: 1841 DAGDTFTFEFVSGEGDLDNDKFTL--VDGALRTAEATDDAIQALYSIRVRVTDSDGLTFE 1898 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG 728 T + + E++ +P D T +++ + GTT+G A D ++ + Sbjct: 1899 DTADLIVTEENV--APTAILLDATT--VADGAASGTTVGTFTATDANDFDEHTFEFVAGE 1954 Query: 729 GD-DSNSFSL 737 GD D+ SF++ Sbjct: 1955 GDTDNASFTI 1964 Score = 139 bits (336), Expect = 1e-30 Identities = 199/801 (24%), Positives = 314/801 (39%), Gaps = 73/801 (9%) Query: 45 LKATDQDIGKNAEVEYTI-ELVTADTLNPEDAXXXXXXXXXXVQDV-FRIDGRSGALLTR 102 + +D I +N ++ +L T D+ + D F I G S L+ Sbjct: 515 ISLSDTSIAENEAASTSVGDLSTTDSNTGDTFTYSIVSIDGSTTDTTFAISGNS--LVAT 572 Query: 103 ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDED 162 SLD E + YTV+V+ TDQ LS T +N+ D N E +++ +D Sbjct: 573 ESLDFETKSSYTVVVRTTDQGG-----LSFDQTFTINVDDIN-------EAPTAIALSDD 620 Query: 163 ISVTDNPVIAKI--KATDADVGANSAIRYAIIGGNTQM-QFSIDSLSGDVSLVKTLDYEQ 219 SV D+ V + T DV A+ YA++ G S + ++ T+D++ Sbjct: 621 -SVADDSVSGTVVGSFTTTDVDASDTFTYALVSGTGDTDNASFTIVGNELRTATTIDFDT 679 Query: 220 VRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRV 279 SY + I+ D G T + + I V N SL +V+EN G ++ Sbjct: 680 QSSYSIRIQTTDSG----GETFEQVFTI--VQSNEGPTAISLSDSTVAENGSAGDTVGTF 733 Query: 280 QAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTAT 339 + D G T+ + D N I D + T+G LD ETQ + V +T Sbjct: 734 SSTDPTSGDTFTYTFVTGEGD-DDNALFQIDGDE----LQTAGSLDAETQGTLTIRVRST 788 Query: 340 DGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRL 399 D T T + G + +A EP GT V TL D D + + Sbjct: 789 DSTGEFTEETFTITVSSVNEAPTTIT-LSGTH---VATGEPSGTTVGTLGTDDPDSGDTI 844 Query: 400 HYE-ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQIN 458 Y ++G S T NG L+T A + + + Y + V A D+ G S I Sbjct: 845 TYTLVSGTGDTDNASFTISNGE-LVT-AFAANQQTQSSYSVRVRAQDADGLSTEETFTIT 902 Query: 459 ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518 IT + N AP A V E+A IGTTV +S TD++ Y+L S + Sbjct: 903 IT-STNVAPT-AIAIDNNDVEENADIGTTVGTLSTTDANT--MDSFVYTLVSGTGDT--- 955 Query: 519 HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578 + F I+ + T LD ET S Y + + + D LS I+ +VND Sbjct: 956 -DNASFAIDGNN--LVTAASLDFETQSSYSVRIQSTDPF--GLSTVETFTITATNVNDAP 1010 Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGV 638 + + I ED GT+V TD D + Y L D + + + Sbjct: 1011 TAI--AIDNSTIAEDTASGTTVGSFTTTDDDA--SDTFTYALVSGDGDTDNAAFTISGNN 1066 Query: 639 IRTNKALDRESVATHDLKAVAID--GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696 + T D E+ +++ ++ D G T Q ++ I + D N+ P D I Sbjct: 1067 LVTATTFDFETQSSYSIRVQTTDSAGATFEQ----VLTITVTDTNEVPTAISLD--NSSI 1120 Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756 SE++ GTT+G D D Y++ G+ + T G + LVT D+ Sbjct: 1121 SEDAASGTTVGAFSTTDADASDTFT--YTLVSGEGDTDNAAFTISGGN---LVTATTFDF 1175 Query: 757 ESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN--YKDCFPVG-PF 813 ++ + Y IR + ++L + +N I +N ++ VG Sbjct: 1176 DT-QSSYS--IRVQTEDSAGATFEQVLTITITENEANQTPTAISIDNTDIEEHATVGTTV 1232 Query: 814 GRVPAYDADVTDKLQYRILSG 834 G + DA+ +D Y ++SG Sbjct: 1233 GSLSTTDANASDTFTYALVSG 1253 Score = 132 bits (319), Expect = 1e-28 Identities = 204/830 (24%), Positives = 328/830 (39%), Gaps = 87/830 (10%) Query: 12 NVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLN 71 N+ D D + +V E + GT+V T D D G Y + T DT N Sbjct: 402 NIPDLPDAQAPTNISLSSTTVAENVAVGTSVGTFSTMDPDSGDTHT--YALVSGTGDTDN 459 Query: 72 PEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLS 131 F I G + LLT D YT+ V+ TD +R+ Sbjct: 460 SS----------------FTISGNT--LLTAEVFDSSVQDTYTIRVQTTDSTGRTLERVF 501 Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAI 191 + + + D N S +++ +E S + + + TD++ G Y+I Sbjct: 502 T-----LTVTDQNVAPTGISLSDTSIAENEAASTS----VGDLSTTDSNTG--DTFTYSI 550 Query: 192 I---GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 + G T F+I S + ++LD+E SY +V+R D G S T IN+ Sbjct: 551 VSIDGSTTDTTFAISGNS--LVATESLDFETKSSYTVVVRTTDQGGLSFDQT--FTINVD 606 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD-L 307 D+N+ AP +L +SV+++ G + D D A T+T TG+ D Sbjct: 607 DINE-APT-AIALSDDSVADDSVSGTVVGSFTTTDVD----ASDTFTYALVSGTGDTDNA 660 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFM 367 TI + T+ +D +TQ+ Y + + TD G T Sbjct: 661 SFTIVGNE--LRTATTIDFDTQSSYSIRIQTTDSGGETFEQVFTIVQSNEGPTAISLS-- 716 Query: 368 PGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ 427 + +AE+ G V T ++TD + Y G ++ +G L T A Sbjct: 717 ----DSTVAENGSAGDTVGTFSSTDPTSGDTFTYTFVTGEGDDDNALFQIDGDELQT-AG 771 Query: 428 PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 LD + + + V +TDS G I ++ N AP T V P GTT Sbjct: 772 SLDAETQGTLTIRVRSTDSTGEFTEETFTITVSSVNE-APTTITLSGT-HVATGEPSGTT 829 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 V + D D G ITY+L S + + F I+ G + T +++T S Y Sbjct: 830 VGTLGTDDPDSG--DTITYTLVSGTGDT----DNASFTIS--NGELVTAFAANQQTQSSY 881 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 + V A+D S +T + I+ +V ++ E+A +GT+V + TD Sbjct: 882 SVRVRAQDADGLSTEETFTITITSTNVAPTAIAIDNN----DVEENADIGTTVGTLSTTD 937 Query: 608 ADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQ 667 A+ + D + SF ID + V T +LD E+ +++ ++ + D P Sbjct: 938 ANTMDSFVYTLVSGTGDTDNASFAIDGNNLV--TAASLDFETQSSYSVRIQSTD---PFG 992 Query: 668 SSTV-IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 STV I ++ND+P D T I+E++ GTT+G D D Y++ Sbjct: 993 LSTVETFTITATNVNDAPTAIAIDNST--IAEDTASGTTVGSFTTTDDDASDTFT--YAL 1048 Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA-SPPLWNDVRVEILVT 785 GD + T G++ LVT D+E+ + Y + ++ S + + I VT Sbjct: 1049 VSGDGDTDNAAFTISGNN---LVTATTFDFET-QSSYSIRVQTTDSAGATFEQVLTITVT 1104 Query: 786 DVND-NAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSG 834 D N+ + D I + VG F DAD +D Y ++SG Sbjct: 1105 DTNEVPTAISLDNSSISEDAASGTTVGAFSTT---DADASDTFTYTLVSG 1151 Score = 115 bits (276), Expect = 2e-23 Identities = 151/620 (24%), Positives = 249/620 (40%), Gaps = 57/620 (9%) Query: 227 IRAQDGGSP-SRSNTTQLLI-----NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQ 280 + QDG SP S+ + ++ NI D+ D SL +V+ENV +G S+ Sbjct: 377 VTGQDGLSPLDASDLLRRVVGLSTPNIPDLPDAQAPTNISLSSTTVAENVAVGTSVGTFS 436 Query: 281 AYDADEGVNAELTYTMTDKDYTGNVD-LPITIDPRSGWVYTSGQLDRETQAKYQLLVTAT 339 D D G T+T TG+ D TI + + T+ D Q Y + V T Sbjct: 437 TMDPDSGD----THTYALVSGTGDTDNSSFTISGNT--LLTAEVFDSSVQDTYTIRVQTT 490 Query: 340 DGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRL 399 D T + +AE+E T V L+ TD++ + Sbjct: 491 DSTGRTLERVFTLTVTDQNVAPTGISLS----DTSIAENEAASTSVGDLSTTDSNTGDTF 546 Query: 400 HYEIT---GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQ 456 Y I G T F+I+ G L+ + LDF+ + Y + V TD GG S Sbjct: 547 TYSIVSIDGSTTDTTFAIS---GNSLVAT-ESLDFETKSSYTVVVRTTDQGGLSFDQTFT 602 Query: 457 INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA 516 IN+ D N AP A SV +D+ GT +V S T +DV + TY+L +S Sbjct: 603 INVDDINE-APT-AIALSDDSVADDSVSGT--VVGSFTTTDVDASDTFTYAL---VSGTG 655 Query: 517 VAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVND 576 + ++ + TT +D +T S Y + + D G +T + ++V N+ Sbjct: 656 DTDNASFTIVGNELRTATT---IDFDTQSSYSIRIQTTDSG----GETFEQVFTIVQSNE 708 Query: 577 NEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPAS 636 L + + E+ G +V +TD G + D + F ID Sbjct: 709 GPTAI--SLSDSTVAENGSAGDTVGTFSSTDPTSGDTFTYTFVTGEGDDDNALFQID--G 764 Query: 637 GVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696 ++T +LD E+ T ++ + D T I + +N++P ++ Sbjct: 765 DELQTAGSLDAETQGTLTIRVRSTDSTGEFTEETFT--ITVSSVNEAPTTITLS--GTHV 820 Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756 + P GTT+G + DPD G + + + + G D+++ S G ELVT + Sbjct: 821 ATGEPSGTTVGTLGTDDPDSG-DTITYTLVSGTGDTDNASFTISNG----ELVTAFAANQ 875 Query: 757 ESPRKKYELVIRAA-SPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFG 814 ++ + Y + +RA + L + I +T N AP I N+ ++ +G G Sbjct: 876 QT-QSSYSVRVRAQDADGLSTEETFTITITSTN-VAPTA--IAIDNNDVEENADIGTTVG 931 Query: 815 RVPAYDADVTDKLQYRILSG 834 + DA+ D Y ++SG Sbjct: 932 TLSTTDANTMDSFVYTLVSG 951 Score = 90.6 bits (215), Expect = 5e-16 Identities = 136/553 (24%), Positives = 222/553 (40%), Gaps = 72/553 (13%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+V D N+ + +SV E +SGT V L TD D G +T LV+ D Sbjct: 1503 ISVTDVNETPTAIAIDN--SSVAEDVASGTVVGALSTTDADAGDT----FTYALVSGDG- 1555 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 + ++A F IDG + L+T + D E Y+V V+ TD SD Sbjct: 1556 DTDNAS-------------FTIDGSN--LVTATTFDFETQDSYSVRVQTTD-----SDGA 1595 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 + T+ ++I D N+ S + V+ D T + TD D A+ Y Sbjct: 1596 TFEQTLTISITDVNEAPTAISISSSVVTEDS----TSGTTVGSFSTTDVD--ASDTFTYT 1649 Query: 191 IIGGN---TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 ++ G+ F+ID G++ TLD + SY + +R+ D G T I + Sbjct: 1650 LVAGDGDTDNASFTIDG--GNLVTATTLDMDTQSSYSIRVRSTDAGGSFVEQT--FTITV 1705 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 + N +AP +L +++EN IG + + DAD V TY++ G+ D Sbjct: 1706 TETN-SAPTAI-ALDDATIAENAAIGTVVGALSTTDAD--VADTFTYSLVSG--VGDTDN 1759 Query: 308 PI-TIDPRSGWVYTSGQLDRETQAKYQLLVTATDG-GDPPRSATATXXXXXXXXXXXXXX 365 + ID G + T+ D ETQ+ Y + + ++D G+ + Sbjct: 1760 ALFAID--GGNLVTAATFDFETQSSYSVRIQSSDAVGETVSQSFVITVVDINDAPTGLTL 1817 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGN---TRGRFSITSQNGRGL 422 P +A + G V L A D D + +E G +F++ G Sbjct: 1818 PFPA-----IASGQASGFLVGNLGAEDQDAGDTFTFEFVSGEGDLDNDKFTLVD----GA 1868 Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 + A+ D + Y + V TDS G + + +T+ N AP T +V + A Sbjct: 1869 LRTAEATDDAIQALYSIRVRVTDSDGLTFEDTADLIVTE-ENVAPTAILLDAT-TVADGA 1926 Query: 483 PIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 GTTV +ATD++ + ++ E + +++ G +TTN D Sbjct: 1927 ASGTTVGTFTATDANDFDEHTFEF-----VAGEGDTDNASFTIVD---GVLTTNFEADAS 1978 Query: 543 TMSGYLLTVTARD 555 T S Y + V + D Sbjct: 1979 TQSSYSIRVLSTD 1991 >UniRef50_Q4RIZ0 Cluster: Chromosome undetermined SCAF15040, whole genome shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome undetermined SCAF15040, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 839 Score = 167 bits (407), Expect = 3e-39 Identities = 146/547 (26%), Positives = 247/547 (45%), Gaps = 49/547 (8%) Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYE 218 + E+ + +D I K+++ D D G N ++Y + G F ID +GD+ + LD E Sbjct: 31 LQEEYTGSDYQYIGKLQS-DQDHG-NGLVKYVLSGEGAGNIFIIDENNGDLHATRRLDRE 88 Query: 219 QVRSYRL---VIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275 + Y L V+ + G T+ I + D+NDN P F ++ SV E IG S Sbjct: 89 EKAYYILKATVVNKRTG--QKLEPETEFTIKLHDINDNEPHFSQEVYTGSVPERSDIGTS 146 Query: 276 IVRVQAYDADEGV---NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS---GQLDRETQ 329 +++V A DAD+G+ +A+L Y+++ G+ ++DP +G + T+ G +DRE + Sbjct: 147 VIQVTATDADDGMYGNSAKLVYSISQ----GHP--YFSVDPNTGVIRTALGPGDMDREQR 200 Query: 330 AKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX--XFMPGQYEVELAEDEPPGTPVVT 387 YQ+++ A D T T F Y+ + E GTPV Sbjct: 201 EHYQVVIEAKDMAGQRGGLTGTTVVNITLTDVNDNPPRFTQSIYQFRVPESSESGTPVGR 260 Query: 388 LTATDAD--EDNRLHYEITGGNTRGRFSITSQNG--RGLITVAQPLDFKQERRYVLTVSA 443 + A D D E+ +++ I G+ F I + G+ITV++PLD++++ Y + + Sbjct: 261 IRAADKDIGENAEMYFTIVSGDGLDTFDIFTDKATQEGVITVSKPLDYEKKPSYTVEIQV 320 Query: 444 TD--------SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495 + S G D A V+I + D + P+F+ A Y V EDA +G + VSA D Sbjct: 321 QNTQIDPRFMSPGSKDVATVRIAVEDVDE-PPLFDKASYLMEVKEDAAVGVALGSVSAID 379 Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555 D G + Y++ D F ++P G++ K LDRE + + ++V A + Sbjct: 380 PD-GARNIVKYAIDRR------TDMDHLFNVHPGNGSVFLLKSLDREESAWHNISVIATE 432 Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG- 614 S V I ++DVNDN P +Y + + V A D D G Sbjct: 433 LHNSRQSSHVPVFIHLLDVNDNAPTL-ATVYETFVSRPN--QNRIQTVRAVDVDEPSAGH 489 Query: 615 RIHYELDPKDREEGSFVI----DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSST 670 + ++ L P+ +F I D + ++ + R + + + V DG P QSST Sbjct: 490 KFYFSLAPEGTYRSNFTIRDNGDNTASILTRRASYSRLQQSMYLVPVVITDGDYPMQSST 549 Query: 671 VIVHIKI 677 + +++ Sbjct: 550 GTLTVRV 556 Score = 152 bits (369), Expect = 1e-34 Identities = 136/486 (27%), Positives = 217/486 (44%), Gaps = 33/486 (6%) Query: 283 DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG 342 D D G N + Y ++ + GN+ + ID +G ++ + +LDRE +A Y L T + Sbjct: 49 DQDHG-NGLVKYVLSGEG-AGNIFI---IDENNGDLHATRRLDREEKAYYILKATVVNKR 103 Query: 343 DPPRSATATXXXXXXXXXXXXX-XFMPGQYEVELAEDEPPGTPVVTLTATDADE-----D 396 + T F Y + E GT V+ +TATDAD+ Sbjct: 104 TGQKLEPETEFTIKLHDINDNEPHFSQEVYTGSVPERSDIGTSVIQVTATDADDGMYGNS 163 Query: 397 NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR--YVLTVSATDS----GGRS 450 +L Y I+ G+ FS+ G + T P D +E+R Y + + A D GG + Sbjct: 164 AKLVYSISQGHPY--FSVDPNTGV-IRTALGPGDMDREQREHYQVVIEAKDMAGQRGGLT 220 Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510 T +V I +TD N+ P F + Y V E + GT V + A D D+G NA++ +++ Sbjct: 221 GTTVVNITLTDVNDNPPRFTQSIYQFRVPESSESGTPVGRIRAADKDIGENAEMYFTI-- 278 Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV------PSLSDT 564 +S + + D Q G IT +K LD E Y + + ++ + P D Sbjct: 279 -VSGDGLDTFDIFTDKATQEGVITVSKPLDYEKKPSYTVEIQVQNTQIDPRFMSPGSKDV 337 Query: 565 TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624 V I+V DV D P+F + Y + EDA VG ++ V A D D G + Y +D + Sbjct: 338 ATVRIAVEDV-DEPPLFDKASYLMEVKEDAAVGVALGSVSAIDPD-GARNIVKYAIDRRT 395 Query: 625 REEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP 684 + F + P +G + K+LDRE A H++ +A + QSS V V I + D+ND+ Sbjct: 396 DMDHLFNVHPGNGSVFLLKSLDREESAWHNISVIATELHNSRQSSHVPVFIHLLDVNDNA 455 Query: 685 PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD 744 P + TF N T+ + +P G + +G SN F++ G + Sbjct: 456 PTLATVYETFVSRPNQNRIQTVRAVDVDEPSAGHKFYFSLAPEGTYRSN-FTIRD-NGDN 513 Query: 745 KAELVT 750 A ++T Sbjct: 514 TASILT 519 Score = 146 bits (353), Expect = 1e-32 Identities = 123/424 (29%), Positives = 197/424 (46%), Gaps = 33/424 (7%) Query: 391 TDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL--TVSATDSGG 448 +D D N L + G G I +N G + + LD +++ Y+L TV +G Sbjct: 48 SDQDHGNGLVKYVLSGEGAGNIFIIDENN-GDLHATRRLDREEKAYYILKATVVNKRTGQ 106 Query: 449 RSDTAM-VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI---NAQI 504 + + I + D N+ P F YT SV E + IGT+V+ V+ATD+D G+ +A++ Sbjct: 107 KLEPETEFTIKLHDINDNEPHFSQEVYTGSVPERSDIGTSVIQVTATDADDGMYGNSAKL 166 Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL---LDRETMSGYLLTVTARD--GGVP 559 YS+S H F ++P TG I T +DRE Y + + A+D G Sbjct: 167 VYSISQ-------GH--PYFSVDPNTGVIRTALGPGDMDREQREHYQVVIEAKDMAGQRG 217 Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619 L+ TT V I++ DVNDN P F Q +Y + E + GT V ++ A D D+G N +++ Sbjct: 218 GLTGTTVVNITLTDVNDNPPRFTQSIYQFRVPESSESGTPVGRIRAADKDIGENAEMYFT 277 Query: 620 LDPKDR-EEGSFVIDPAS--GVIRTNKALDRESVATHDLKA----VAIDGG--TPPQSST 670 + D + D A+ GVI +K LD E ++ ++ ID +P Sbjct: 278 IVSGDGLDTFDIFTDKATQEGVITVSKPLDYEKKPSYTVEIQVQNTQIDPRFMSPGSKDV 337 Query: 671 VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGD 730 V I +ED+ D PP+F+ + E++ +G +G + A DPD G +V Y+I Sbjct: 338 ATVRIAVEDV-DEPPLFDKASYLMEVKEDAAVGVALGSVSAIDPD-GARNIVKYAIDRRT 395 Query: 731 DSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDN 790 D + G+ L+ +D + + + + + V V I + DVNDN Sbjct: 396 DMDHL-FNVHPGNGSVFLLKSLDREESAWHNISVIATELHNSRQSSHVPVFIHLLDVNDN 454 Query: 791 APVM 794 AP + Sbjct: 455 APTL 458 Score = 144 bits (350), Expect = 2e-32 Identities = 109/343 (31%), Positives = 162/343 (47%), Gaps = 23/343 (6%) Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553 +D D G N + Y LS E + F+I+ G + + LDRE + Y+L T Sbjct: 48 SDQDHG-NGLVKYVLSGEGAGNI-------FIIDENNGDLHATRRLDREEKAYYILKATV 99 Query: 554 RDGGV-PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612 + L T+ I + D+NDNEP F Q++YT ++ E + +GTSV QV ATDAD G+ Sbjct: 100 VNKRTGQKLEPETEFTIKLHDINDNEPHFSQEVYTGSVPERSDIGTSVIQVTATDADDGM 159 Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKA---LDRESVATHDLKAVAID--GGTPPQ 667 G + + F +DP +GVIRT +DRE + + A D G Sbjct: 160 YGNSAKLVYSISQGHPYFSVDPNTGVIRTALGPGDMDREQREHYQVVIEAKDMAGQRGGL 219 Query: 668 SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIK 727 + T +V+I + D+ND+PP F F + E+S GT +G IRA D D G NA ++++I Sbjct: 220 TGTTVVNITLTDVNDNPPRFTQSIYQFRVPESSESGTPVGRIRAADKDIGENAEMYFTIV 279 Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYE-SPRKKYELVI-------RAASPPLWNDVR 779 GD ++F + T + + + + LDYE P E+ + R SP + Sbjct: 280 SGDGLDTFDIFTDKATQEGVITVSKPLDYEKKPSYTVEIQVQNTQIDPRFMSPGSKDVAT 339 Query: 780 VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDAD 822 V I V DV D P+ + +D G V A D D Sbjct: 340 VRIAVEDV-DEPPLFDKASYLMEVKEDAAVGVALGSVSAIDPD 381 Score = 137 bits (332), Expect = 4e-30 Identities = 139/504 (27%), Positives = 215/504 (42%), Gaps = 35/504 (6%) Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 ++F ID +G L LDRE+ A Y ++KAT +L + + D NDN Sbjct: 68 NIFIIDENNGDLHATRRLDREEKAYY--ILKATVVNKRTGQKLEPETEFTIKLHDINDNE 125 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG--ANSA-IRYAIIGGNTQMQFSIDS 204 P FS++ YT SV E + + + ++ ATDAD G NSA + Y+I G+ FS+D Sbjct: 126 PHFSQEVYTGSVPERSDIGTS--VIQVTATDADDGMYGNSAKLVYSISQGHPY--FSVDP 181 Query: 205 LSGDVSLVK---TLDYEQVRSYRLVIRAQD--GGSPSRSNTTQLLINIRDVNDNAPRFYT 259 +G + +D EQ Y++VI A+D G + TT + I + DVNDN PRF Sbjct: 182 NTGVIRTALGPGDMDREQREHYQVVIEAKDMAGQRGGLTGTTVVNITLTDVNDNPPRFTQ 241 Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319 S++Q V E+ G + R++A D D G NAE+ +T+ D D+ + G + Sbjct: 242 SIYQFRVPESSESGTPVGRIRAADKDIGENAEMYFTIVSGDGLDTFDIFTDKATQEGVIT 301 Query: 320 TSGQLDRETQAKYQLLVTATDGG-DP----PRSATATXXXXXXXXXXXXXXFMPGQYEVE 374 S LD E + Y + + + DP P S F Y +E Sbjct: 302 VSKPLDYEKKPSYTVEIQVQNTQIDPRFMSPGSKDVATVRIAVEDVDEPPLFDKASYLME 361 Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434 + ED G + +++A D D + T G G + + + LD ++ Sbjct: 362 VKEDAAVGVALGSVSAIDPDGARNIVKYAIDRRTDMDHLFNVHPGNGSVFLLKSLDREES 421 Query: 435 RRYVLTVSATD--SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492 + ++V AT+ + +S V I++ D N+ AP T F P + V Sbjct: 422 AWHNISVIATELHNSRQSSHVPVFIHLLDVNDNAPTLATVYET---FVSRPNQNRIQTVR 478 Query: 493 ATDSD-VGINAQITYSLSSEISNEAVAHHDQQFVI---NPQTGAITTNKL-LDRETMSGY 547 A D D + +SL+ E + F I T +I T + R S Y Sbjct: 479 AVDVDEPSAGHKFYFSLAPE------GTYRSNFTIRDNGDNTASILTRRASYSRLQQSMY 532 Query: 548 LLTVTARDGGVPSLSDTTDVEISV 571 L+ V DG P S T + + V Sbjct: 533 LVPVVITDGDYPMQSSTGTLTVRV 556 Score = 116 bits (279), Expect = 9e-24 Identities = 117/457 (25%), Positives = 199/457 (43%), Gaps = 54/457 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVTA 67 I + D ND+ P F + Y SV E + GT+V+ + ATD D G +A++ Y+I Sbjct: 116 IKLHDINDNEPHFSQEVYTGSVPERSDIGTSVIQVTATDADDGMYGNSAKLVYSI----- 170 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR---ASLDREKVARYTVLVKATDQAS 124 F +D +G + T +DRE+ Y V+++A D A Sbjct: 171 ----------------SQGHPYFSVDPNTGVIRTALGPGDMDREQREHYQVVIEAKDMAG 214 Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN 184 L+ T +++ + D NDN P+F++ Y V E S + PV +I+A D D+G N Sbjct: 215 Q-RGGLTGTTVVNITLTDVNDNPPRFTQSIYQFRVPES-SESGTPV-GRIRAADKDIGEN 271 Query: 185 SAIRYAIIGGNTQMQFSI----DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG------S 234 + + + I+ G+ F I + G +++ K LDYE+ SY + I+ Q+ S Sbjct: 272 AEMYFTIVSGDGLDTFDIFTDKATQEGVITVSKPLDYEKKPSYTVEIQVQNTQIDPRFMS 331 Query: 235 PSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY 294 P + + I + DV D P F + + V E+ +G ++ V A D D G + Y Sbjct: 332 PGSKDVATVRIAVEDV-DEPPLFDKASYLMEVKEDAAVGVALGSVSAIDPD-GARNIVKY 389 Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXX 354 + D ++D + P +G V+ LDRE A + + V AT+ + R ++ Sbjct: 390 AI---DRRTDMDHLFNVHPGNGSVFLLKSLDREESAWHNISVIATELHN-SRQSSHVPVF 445 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE---DNRLHYEIT-GGNTRG 410 + YE ++ P + T+ A D DE ++ ++ + G R Sbjct: 446 IHLLDVNDNAPTLATVYETFVS--RPNQNRIQTVRAVDVDEPSAGHKFYFSLAPEGTYRS 503 Query: 411 RFSI--TSQNGRGLITVAQPLDFKQERRYVLTVSATD 445 F+I N ++T Q+ Y++ V TD Sbjct: 504 NFTIRDNGDNTASILTRRASYSRLQQSMYLVPVVITD 540 Score = 115 bits (277), Expect = 2e-23 Identities = 102/348 (29%), Positives = 161/348 (46%), Gaps = 30/348 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D ND+ P F Y+ V E + SGT V ++A D+DIG+NAE+ +TI V+ D L Sbjct: 227 ITLTDVNDNPPRFTQSIYQFRVPESSESGTPVGRIRAADKDIGENAEMYFTI--VSGDGL 284 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD-QASP--VS 127 + D + G + LD EK YTV ++ + Q P +S Sbjct: 285 DTFDIFTDKAT-------------QEGVITVSKPLDYEKKPSYTVEIQVQNTQIDPRFMS 331 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 AT+ + ++D D P F + +Y + V ED +V + + A D D GA + + Sbjct: 332 PGSKDVATVRI-AVEDVDEPPLFDKASYLMEVKEDAAV--GVALGSVSAIDPD-GARNIV 387 Query: 188 RYAIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 +YA I T M F++ +G V L+K+LD E+ + + + A + + +S+ + I Sbjct: 388 KYA-IDRRTDMDHLFNVHPGNGSVFLLKSLDREESAWHNISVIATELHNSRQSSHVPVFI 446 Query: 246 NIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTY--TMTDKDYTG 303 ++ DVNDNAP T +++ VS P I V+A D DE Y + Y Sbjct: 447 HLLDVNDNAPTLAT-VYETFVSR--PNQNRIQTVRAVDVDEPSAGHKFYFSLAPEGTYRS 503 Query: 304 NVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 N + D + + R Q+ Y + V TDG P +S+T T Sbjct: 504 NFTIRDNGDNTASILTRRASYSRLQQSMYLVPVVITDGDYPMQSSTGT 551 >UniRef50_Q95YK9 Cluster: Type II cadherin; n=1; Ciona savignyi|Rep: Type II cadherin - Ciona savignyi (Pacific transparent sea squirt) Length = 910 Score = 167 bits (407), Expect = 3e-39 Identities = 144/479 (30%), Positives = 213/479 (44%), Gaps = 36/479 (7%) Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I+P SG ++ +LDRE Q+ Y+L V+A DG P + F PG Sbjct: 185 IEPLSGHLFLKQKLDREMQSSYKLNVSAHDGNGVPLEPASEITIDVLDENDNPPEFAPGP 244 Query: 371 YEVELAEDEPPGTPVVTLTATDADEDNRLHYEI------TGGNTRGRFSITSQNGRGLIT 424 + + E P GT V + A DAD+ + + +I + G+ +F I + G + T Sbjct: 245 HHARVKERSPSGTKVADVIARDADDPQQPYGQIRYSLLPSPGDATNKFMIHHERGT-VST 303 Query: 425 VAQPLDFKQERRYVLTVSATDSGGR----SDTAMVQINITDANNYAPVFENAPYTASVFE 480 + LD ++ Y L + A D S T + I++ D N+ PVF N PY V E Sbjct: 304 ITSNLDREESATYELVIQARDDPNARLSFSATTTLTISVIDVNDSPPVFVNEPYKPIVAE 363 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 DA IG+ ++ +S TD+DVG NAQ Y + + A + + N G + K LD Sbjct: 364 DAKIGSEIVRLSTTDADVGENAQSIYVIED---GDDSAMFSIEAIDN--LGVLKVKKRLD 418 Query: 541 RETMSG--YLLTVTARD-------GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 ET Y + V AR+ + S+ D TDV I+V DVN+ P F + Y ++ Sbjct: 419 YETAPDHKYSVRVRARNTHPDPNLAYLGSMDDVTDVVITVTDVNE-PPEFTEVNYEFSVR 477 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA 651 EDA+ G + V A D + Y L +D E F ID SG+I LDRE A Sbjct: 478 EDAIRGFPIRAVTAVDPE---GDSFSYFL--RD-ESKRFAIDAVSGMISVAGELDRELQA 531 Query: 652 THDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP-VFESDCLTFYISENSPIGTTI--GE 708 T+D+ A G ST V I I D+ND+PP + D + + +N I + Sbjct: 532 TYDVTVYAGSPGDLDFRSTARVTISISDVNDNPPHPLDGDTVQVVLCDNQHEKGQILHPK 591 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 I+ DPD N ++ + N E D + Y S ++YEL + Sbjct: 592 IKFTDPDSPING-QPFTYYSTEHDNYKHFELVNNDDGTASLRTAHRGYSSSIREYELPV 649 Score = 149 bits (362), Expect = 8e-34 Identities = 145/536 (27%), Positives = 234/536 (43%), Gaps = 45/536 (8%) Query: 167 DNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLV 226 ++ +IA+++++ + + Y+I G F I+ LSG + L + LD E SY+L Sbjct: 152 EDQLIARLRSSYDNY--TGTVIYSISGRGADSLFQIEPLSGHLFLKQKLDREMQSSYKLN 209 Query: 227 IRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE 286 + A DG +++ I++ D NDN P F V E P G + V A DAD+ Sbjct: 210 VSAHDGNGVPLEPASEITIDVLDENDNPPEFAPGPHHARVKERSPSGTKVADVIARDADD 269 Query: 287 GVN--AELTYTMTDKDYTGNVDLPITIDPRSGWVYT-SGQLDRETQAKYQLLVTATDGGD 343 ++ Y++ G+ I G V T + LDRE A Y+L++ A D + Sbjct: 270 PQQPYGQIRYSLLPSP--GDATNKFMIHHERGTVSTITSNLDREESATYELVIQARDDPN 327 Query: 344 PPRS--ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRL 399 S AT T F+ Y+ +AED G+ +V L+ TDAD E+ + Sbjct: 328 ARLSFSATTTLTISVIDVNDSPPVFVNEPYKPIVAEDAKIGSEIVRLSTTDADVGENAQS 387 Query: 400 HYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ--ERRYVLTVSATDS---------GG 448 Y I G+ FSI + + G++ V + LD++ + +Y + V A ++ G Sbjct: 388 IYVIEDGDDSAMFSIEAIDNLGVLKVKKRLDYETAPDHKYSVRVRARNTHPDPNLAYLGS 447 Query: 449 RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508 D V I +TD N P F Y SV EDA G + V+A D + +Y L Sbjct: 448 MDDVTDVVITVTDVNE-PPEFTEVNYEFSVREDAIRGFPIRAVTAVDPE---GDSFSYFL 503 Query: 509 SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVE 568 E ++F I+ +G I+ LDRE + Y +TV A G T V Sbjct: 504 RDE---------SKRFAIDAVSGMISVAGELDRELQATYDVTVYAGSPGDLDFRSTARVT 554 Query: 569 ISVVDVNDNEPV-----FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR--IHYELD 621 IS+ DVNDN P Q + N E + ++ TD D +NG+ +Y + Sbjct: 555 ISISDVNDNPPHPLDGDTVQVVLCDNQHEKGQI--LHPKIKFTDPDSPINGQPFTYYSTE 612 Query: 622 PKDREEGSFVI-DPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIK 676 + + V D + +RT S+ ++L + D G+P ++T + ++ Sbjct: 613 HDNYKHFELVNNDDGTASLRTAHRGYSSSIREYELPVIVEDNGSPKLNATYTITVR 668 Score = 144 bits (349), Expect = 3e-32 Identities = 130/415 (31%), Positives = 195/415 (46%), Gaps = 44/415 (10%) Query: 401 YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQIN 458 Y I+G F I +G + + Q LD + + Y L VSA D G + + I+ Sbjct: 172 YSISGRGADSLFQIEPLSGH--LFLKQKLDREMQSSYKLNVSAHDGNGVPLEPASEITID 229 Query: 459 ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN--AQITYSL---SSEIS 513 + D N+ P F P+ A V E +P GT V V A D+D QI YSL + + Sbjct: 230 VLDENDNPPEFAPGPHHARVKERSPSGTKVADVIARDADDPQQPYGQIRYSLLPSPGDAT 289 Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD--GGVPSLSDTTDVEISV 571 N+ + HH++ V IT+N LDRE + Y L + ARD S S TT + ISV Sbjct: 290 NKFMIHHERGTV-----STITSN--LDREESATYELVIQARDDPNARLSFSATTTLTISV 342 Query: 572 VDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFV 631 +DVND+ PVF + Y + EDA +G+ + ++ TDADVG N + Y ++ D + F Sbjct: 343 IDVNDSPPVFVNEPYKPIVAEDAKIGSEIVRLSTTDADVGENAQSIYVIEDGD-DSAMFS 401 Query: 632 IDPAS--GVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI---------VHIKIEDI 680 I+ GV++ K LD E+ H T P + V I + D+ Sbjct: 402 IEAIDNLGVLKVKKRLDYETAPDHKYSVRVRARNTHPDPNLAYLGSMDDVTDVVITVTDV 461 Query: 681 NDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETR 740 N+ PP F F + E++ G I + A DP EG + Y ++ D+S F+++ Sbjct: 462 NE-PPEFTEVNYEFSVREDAIRGFPIRAVTAVDP-EGDS--FSYFLR--DESKRFAIDAV 515 Query: 741 QGSDKAELVTMVDLDYESPRKKYELVIRAASP---PLWNDVRVEILVTDVNDNAP 792 G + +LD E + Y++ + A SP + RV I ++DVNDN P Sbjct: 516 SGM----ISVAGELDREL-QATYDVTVYAGSPGDLDFRSTARVTISISDVNDNPP 565 Score = 137 bits (331), Expect = 5e-30 Identities = 122/370 (32%), Positives = 180/370 (48%), Gaps = 27/370 (7%) Query: 521 DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDG-GVPSLSDTTDVEISVVDVNDNEP 579 D F I P +G + + LDRE S Y L V+A DG GVP L +++ I V+D NDN P Sbjct: 180 DSLFQIEPLSGHLFLKQKLDREMQSSYKLNVSAHDGNGVP-LEPASEITIDVLDENDNPP 238 Query: 580 VFKQQLYTANIMEDALVGTSVSQVGATDADVGLN--GRIHYELDPKDRE-EGSFVIDPAS 636 F + A + E + GT V+ V A DAD G+I Y L P + F+I Sbjct: 239 EFAPGPHHARVKERSPSGTKVADVIARDADDPQQPYGQIRYSLLPSPGDATNKFMIHHER 298 Query: 637 GVIRT-NKALDRESVATHDLKAVAID--GGTPPQSSTVIVHIKIEDINDSPPVFESDCLT 693 G + T LDRE AT++L A D S+T + I + D+NDSPPVF ++ Sbjct: 299 GTVSTITSNLDREESATYELVIQARDDPNARLSFSATTTLTISVIDVNDSPPVFVNEPYK 358 Query: 694 FYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD 753 ++E++ IG+ I + D D G NA Y I+ GDDS FS+E + L Sbjct: 359 PIVAEDAKIGSEIVRLSTTDADVGENAQSIYVIEDGDDSAMFSIEAI--DNLGVLKVKKR 416 Query: 754 LDYE-SPRKKYELVIRAAS----PPL-----WNDVR-VEILVTDVNDNAPVMKDFQIIFN 802 LDYE +P KY + +RA + P L +DV V I VTDVN+ P + F+ Sbjct: 417 LDYETAPDHKYSVRVRARNTHPDPNLAYLGSMDDVTDVVITVTDVNE-PPEFTEVNYEFS 475 Query: 803 NYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKL 862 +D P V A D + D Y + + + ++ +G ++++ +L+ + Sbjct: 476 VREDAIRGFPIRAVTAVDPE-GDSFSYFL--RDESKRFAIDAVSGMISVAGELDRELQ-- 530 Query: 863 ATMEVSVTDG 872 AT +V+V G Sbjct: 531 ATYDVTVYAG 540 Score = 134 bits (323), Expect = 4e-29 Identities = 144/501 (28%), Positives = 222/501 (44%), Gaps = 35/501 (6%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +F+I+ SG L + LDRE + Y + V A D + V L + I ++++D+NDN P Sbjct: 182 LFQIEPLSGHLFLKQKLDREMQSSYKLNVSAHD-GNGVP--LEPASEITIDVLDENDNPP 238 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN--SAIRYAII--GGNTQMQFSIDS 204 +F+ + V E +A + A DAD IRY+++ G+ +F I Sbjct: 239 EFAPGPHHARVKE--RSPSGTKVADVIARDADDPQQPYGQIRYSLLPSPGDATNKFMIHH 296 Query: 205 LSGDVS-LVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQLLINIRDVNDNAPRFYTSL 261 G VS + LD E+ +Y LVI+A+D + S S TT L I++ DVND+ P F Sbjct: 297 ERGTVSTITSNLDREESATYELVIQARDDPNARLSFSATTTLTISVIDVNDSPPVFVNEP 356 Query: 262 FQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTS 321 ++ V+E+ IG IVR+ DAD G NA+ Y + D D + + ID G + Sbjct: 357 YKPIVAEDAKIGSEIVRLSTTDADVGENAQSIYVIEDGDDSAMFSIE-AID-NLGVLKVK 414 Query: 322 GQLDRET--QAKYQLLVTATDGGDPPRSA------TATXXXXXXXXXXXXXXFMPGQYEV 373 +LD ET KY + V A + P A T F YE Sbjct: 415 KRLDYETAPDHKYSVRVRARNTHPDPNLAYLGSMDDVTDVVITVTDVNEPPEFTEVNYEF 474 Query: 374 ELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ 433 + ED G P+ +TA D + D+ ++ + RF+I + + G+I+VA LD + Sbjct: 475 SVREDAIRGFPIRAVTAVDPEGDSFSYFL---RDESKRFAIDAVS--GMISVAGELDREL 529 Query: 434 ERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV- 490 + Y +TV A G TA V I+I+D N+ P + V D ++ Sbjct: 530 QATYDVTVYAGSPGDLDFRSTARVTISISDVNDNPPHPLDGDTVQVVLCDNQHEKGQILH 589 Query: 491 --VSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 + TD D IN Q S+E N H + + T ++ T ++ Y Sbjct: 590 PKIKFTDPDSPINGQPFTYYSTEHDN---YKHFELVNNDDGTASLRTAHRGYSSSIREYE 646 Query: 549 LTVTARDGGVPSLSDTTDVEI 569 L V D G P L+ T + + Sbjct: 647 LPVIVEDNGSPKLNATYTITV 667 Score = 93.1 bits (221), Expect = 1e-16 Identities = 95/350 (27%), Positives = 158/350 (45%), Gaps = 34/350 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+V+D ND PVF + Y+ V E A G+ ++ L TD D+G+NA+ Y I Sbjct: 340 ISVIDVNDSPPVFVNEPYKPIVAEDAKIGSEIVRLSTTDADVGENAQSIYVI-------- 391 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVA--RYTVLVKATD-QASPVS 127 ED + ++ G L + LD E +Y+V V+A + P Sbjct: 392 --EDGDDSAMFSIEAIDNL-------GVLKVKKRLDYETAPDHKYSVRVRARNTHPDPNL 442 Query: 128 DRLSS--TATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 L S T V + D + P+F+E Y SV ED ++ P+ A + A D + Sbjct: 443 AYLGSMDDVTDVVITVTDVNEPPEFTEVNYEFSVRED-AIRGFPIRA-VTAVDPE---GD 497 Query: 186 AIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLI 245 + Y + + +F+ID++SG +S+ LD E +Y + + A G +T ++ I Sbjct: 498 SFSYFL--RDESKRFAIDAVSGMISVAGELDRELQATYDVTVYAGSPGDLDFRSTARVTI 555 Query: 246 NIRDVNDNAPR-FYTSLFQESVSENVPIGYSIV--RVQAYDADEGVNAE-LTYTMTDKDY 301 +I DVNDN P Q + +N I+ +++ D D +N + TY T+ D Sbjct: 556 SISDVNDNPPHPLDGDTVQVVLCDNQHEKGQILHPKIKFTDPDSPINGQPFTYYSTEHDN 615 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 + +L + D + + T+ + + +Y+L V D G P +AT T Sbjct: 616 YKHFEL-VNNDDGTASLRTAHRGYSSSIREYELPVIVEDNGSPKLNATYT 664 >UniRef50_Q5NUI3 Cluster: Cadherin19; n=12; Mammalia|Rep: Cadherin19 - Rattus norvegicus (Rat) Length = 770 Score = 167 bits (406), Expect = 4e-39 Identities = 144/507 (28%), Positives = 235/507 (46%), Gaps = 39/507 (7%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F ID ++G + LDREK + Y + + D + + + + + + D NDN P+ Sbjct: 88 FSIDEKTGDIFAMQKLDREKQSLYILRAQVID--TTIGKAVEPESEFVIRVSDVNDNEPR 145 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDAD---VGANSAIRYAIIGGNTQMQFSIDSLS 206 F ++ Y V E + + K+ A DAD G ++ I Y + G Q FS++ + Sbjct: 146 FLDEPYEAIVPE--MSPEGTFVIKVTANDADDPTSGYHARILYNLEQG--QPYFSVEPTT 201 Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDG-GSPSR-SNTTQLLINIRDVNDNAPRFYTSLFQE 264 G + + +D E +Y ++I+A+D G P S TT + I + D+NDN P F S ++ Sbjct: 202 GVIRISSKMDRELQDTYCVIIQAKDMLGQPGALSGTTTISIKLSDINDNKPIFKESFYRF 261 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 ++SE+ P G +I ++ AYD D G NAE+ Y++ D D + D+ I + + G V ++ Sbjct: 262 TISESAPSGTTIGKIMAYDDDIGENAEMDYSIED-DESQIFDIVIDNETQEGIVILKKKV 320 Query: 325 DRETQAKYQLLVTA----TDGGDPPR--SATATXXXXXXXXXXXXXXFMPGQYEVELAED 378 D E Q Y + V D P +A+ T F+ Y E+ E Sbjct: 321 DFEHQNHYGIRVKVKNCHVDEELAPAHVNASTTYIKVQVEDEDEPPTFLLPYYIFEIPEG 380 Query: 379 EPPGTPVVTLTATDAD-EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRY 437 +P GT V T++A D D + + Y + G F I NG G I LD + Y Sbjct: 381 KPYGTMVGTVSAVDPDRRQSPMRYSLIGSK---MFDI---NGNGTIVTTNLLDREVSAWY 434 Query: 438 VLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATD 495 L+V+AT++ + +A V + + + N++AP F Y V E+A G + +SA D Sbjct: 435 NLSVTATETYNVQQISSAHVYVQVLNINDHAPEFSQL-YETYVCENAESGEIIQTISAID 493 Query: 496 SDVGINAQITYSLSS--EISNEAVAHHDQQFVINPQTGAITTNKL---LDRETMSGYLLT 550 D I Y S + +N + D Q T I +N+ L ET+ + + Sbjct: 494 RDESIEDHHFYFNHSVEDTNNSSFILTDNQ----DNTAVILSNRAGFSLKEETV--FYMI 547 Query: 551 VTARDGGVPSLSDTTDVEISVVDVNDN 577 + D G+P L+ T + I V D D+ Sbjct: 548 ILIADNGIPPLTSTNTLTIQVCDCGDS 574 Score = 150 bits (364), Expect = 5e-34 Identities = 140/530 (26%), Positives = 233/530 (43%), Gaps = 45/530 (8%) Query: 177 TDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG-SP 235 +D D G NS +Y ++G FSID +GD+ ++ LD E+ Y L + D Sbjct: 67 SDLDNGNNS-FQYKLLGTGDG-SFSIDEKTGDIFAMQKLDREKQSLYILRAQVIDTTIGK 124 Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE---GVNAEL 292 + ++ +I + DVNDN PRF ++ V E P G +++V A DAD+ G +A + Sbjct: 125 AVEPESEFVIRVSDVNDNEPRFLDEPYEAIVPEMSPEGTFVIKVTANDADDPTSGYHARI 184 Query: 293 TYTMTD-KDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDG-GDPPR-SAT 349 Y + + Y +++P +G + S ++DRE Q Y +++ A D G P S T Sbjct: 185 LYNLEQGQPY-------FSVEPTTGVIRISSKMDRELQDTYCVIIQAKDMLGQPGALSGT 237 Query: 350 ATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGN 407 T F Y ++E P GT + + A D D E+ + Y I Sbjct: 238 TTISIKLSDINDNKPIFKESFYRFTISESAPSGTTIGKIMAYDDDIGENAEMDYSIEDDE 297 Query: 408 TR-GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT------ 460 ++ I ++ G++ + + +DF+ + Y + V + + A +N + Sbjct: 298 SQIFDIVIDNETQEGIVILKKKVDFEHQNHYGIRVKVKNCHVDEELAPAHVNASTTYIKV 357 Query: 461 --DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA 518 + + P F Y + E P GT V VSA D D + + YSL Sbjct: 358 QVEDEDEPPTFLLPYYIFEIPEGKPYGTMVGTVSAVDPDRR-QSPMRYSLIGS------- 409 Query: 519 HHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578 + F IN G I T LLDRE + Y L+VTA + + V + V+++ND+ Sbjct: 410 ---KMFDINGN-GTIVTTNLLDREVSAWYNLSVTATETYNVQQISSAHVYVQVLNINDHA 465 Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGL-NGRIHYELDPKDREEGSFVI---DP 634 P F QLY + E+A G + + A D D + + ++ +D SF++ Sbjct: 466 PEF-SQLYETYVCENAESGEIIQTISAIDRDESIEDHHFYFNHSVEDTNNSSFILTDNQD 524 Query: 635 ASGVIRTNKA-LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDS 683 + VI +N+A + + + D G PP +ST + I++ D DS Sbjct: 525 NTAVILSNRAGFSLKEETVFYMIILIADNGIPPLTSTNTLTIQVCDCGDS 574 Score = 142 bits (343), Expect = 2e-31 Identities = 136/506 (26%), Positives = 213/506 (42%), Gaps = 31/506 (6%) Query: 303 GNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPPRSATATXXXXXXXXXX 361 G D +ID ++G ++ +LDRE Q+ Y L D + Sbjct: 82 GTGDGSFSIDEKTGDIFAMQKLDREKQSLYILRAQVIDTTIGKAVEPESEFVIRVSDVND 141 Query: 362 XXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR-LHYEITGGNTRGRFSITSQNGR 420 F+ YE + E P GT V+ +TA DAD+ H I +G+ + + Sbjct: 142 NEPRFLDEPYEAIVPEMSPEGTFVIKVTANDADDPTSGYHARILYNLEQGQPYFSVEPTT 201 Query: 421 GLITVAQPLDFKQERRYVLTVSATDS----GGRSDTAMVQINITDANNYAPVFENAPYTA 476 G+I ++ +D + + Y + + A D G S T + I ++D N+ P+F+ + Y Sbjct: 202 GVIRISSKMDRELQDTYCVIIQAKDMLGQPGALSGTTTISIKLSDINDNKPIFKESFYRF 261 Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTN 536 ++ E AP GTT+ + A D D+G NA++ YS+ + S D + Q G + Sbjct: 262 TISESAPSGTTIGKIMAYDDDIGENAEMDYSIEDDESQIFDIVIDNE----TQEGIVILK 317 Query: 537 KLLDRETMSGYLLTVTARDGGVPSL-------SDTTDVEISVVDVNDNEPVFKQQLYTAN 589 K +D E + Y + V ++ V + TT +++ V D D P F Y Sbjct: 318 KKVDFEHQNHYGIRVKVKNCHVDEELAPAHVNASTTYIKVQVED-EDEPPTFLLPYYIFE 376 Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID-PASGVIRTNKALDRE 648 I E GT V V A D D + Y L GS + D +G I T LDRE Sbjct: 377 IPEGKPYGTMVGTVSAVDPD-RRQSPMRYSLI------GSKMFDINGNGTIVTTNLLDRE 429 Query: 649 SVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 A ++L A + Q S+ V++++ +IND P F S Y+ EN+ G I Sbjct: 430 VSAWYNLSVTATETYNVQQISSAHVYVQVLNINDHAPEF-SQLYETYVCENAESGEIIQT 488 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSN--SFSLETRQGSDKAELVTMVDLDYESPRKKYELV 766 I A D DE Y +D+N SF L Q + L + Y ++ Sbjct: 489 ISAIDRDESIEDHHFYFNHSVEDTNNSSFILTDNQDNTAVILSNRAGFSLKEETVFYMII 548 Query: 767 IRAAS--PPLWNDVRVEILVTDVNDN 790 + A + PPL + + I V D D+ Sbjct: 549 LIADNGIPPLTSTNTLTIQVCDCGDS 574 Score = 112 bits (269), Expect = 2e-22 Identities = 118/457 (25%), Positives = 194/457 (42%), Gaps = 56/457 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVTA 67 I V D ND+ P F + YEA V E + GT V+ + A D D G +A + Y +E Sbjct: 134 IRVSDVNDNEPRFLDEPYEAIVPEMSPEGTFVIKVTANDADDPTSGYHARILYNLE---- 189 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 Q F ++ +G + + +DRE Y V+++A D Sbjct: 190 -----------------QGQPYFSVEPTTGVIRISSKMDRELQDTYCVIIQAKDMLGQ-P 231 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 LS T TI + + D NDN P F E Y ++ E S I KI A D D+G N+ + Sbjct: 232 GALSGTTTISIKLSDINDNKPIFKESFYRFTISE--SAPSGTTIGKIMAYDDDIGENAEM 289 Query: 188 RYAIIGGNTQMQFSI----DSLSGDVSLVKTLDYEQVRSYRLVIRAQ-----DGGSPSRS 238 Y+I +Q+ F I ++ G V L K +D+E Y + ++ + + +P+ Sbjct: 290 DYSIEDDESQI-FDIVIDNETQEGIVILKKKVDFEHQNHYGIRVKVKNCHVDEELAPAHV 348 Query: 239 N--TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 N TT + + + D D P F + + E P G + V A D D + + Y++ Sbjct: 349 NASTTYIKVQVED-EDEPPTFLLPYYIFEIPEGKPYGTMVGTVSAVDPDRR-QSPMRYSL 406 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXX 356 G+ I +G + T+ LDRE A Y L VTAT+ + + ++A Sbjct: 407 -----IGSKMFDIN---GNGTIVTTNLLDREVSAWYNLSVTATETYNVQQISSAHVYVQV 458 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEITGGNT-RGRF 412 F YE + E+ G + T++A D D ED+ ++ + +T F Sbjct: 459 LNINDHAPEFSQ-LYETYVCENAESGEIIQTISAIDRDESIEDHHFYFNHSVEDTNNSSF 517 Query: 413 SITSQNGRGLITVAQPLDF--KQERRYVLTVSATDSG 447 +T + ++ F K+E + + + D+G Sbjct: 518 ILTDNQDNTAVILSNRAGFSLKEETVFYMIILIADNG 554 Score = 100 bits (240), Expect = 5e-19 Identities = 87/347 (25%), Positives = 152/347 (43%), Gaps = 31/347 (8%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D ND+ P+F+ Y ++ E A SGTT+ + A D DIG+NAE++Y+IE Sbjct: 242 IKLSDINDNKPIFKESFYRFTISESAPSGTTIGKIMAYDDDIGENAEMDYSIE------- 294 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKA----TDQASPV 126 +D V + + G ++ + +D E Y + VK D+ Sbjct: 295 --DDESQIFDI-------VIDNETQEGIVILKKKVDFEHQNHYGIRVKVKNCHVDEELAP 345 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 + +ST I V ++D D P F Y + E ++ + A D D S Sbjct: 346 AHVNASTTYIKVQ-VEDEDEPPTFLLPYYIFEIPE--GKPYGTMVGTVSAVDPD-RRQSP 401 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 +RY++IG F I+ +G + LD E Y L + A + + + ++ + + Sbjct: 402 MRYSLIGSK---MFDING-NGTIVTTNLLDREVSAWYNLSVTATETYNVQQISSAHVYVQ 457 Query: 247 IRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVD 306 + ++ND+AP F + L++ V EN G I + A D DE + Y + T N Sbjct: 458 VLNINDHAPEF-SQLYETYVCENAESGEIIQTISAIDRDESIEDHHFYFNHSVEDTNNSS 516 Query: 307 LPITIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGGDPPRSATAT 351 +T + + V S + + + + +++ D G PP ++T T Sbjct: 517 FILTDNQDNTAVILSNRAGFSLKEETVFYMIILIADNGIPPLTSTNT 563 Score = 72.1 bits (169), Expect = 2e-10 Identities = 71/264 (26%), Positives = 128/264 (48%), Gaps = 29/264 (10%) Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 ++ VG +D+ NG ++ +GSF ID +G I + LDRE + + L+A Sbjct: 58 TIQHVGRLRSDLD-NGNNSFQYKLLGTGDGSFSIDEKTGDIFAMQKLDREKQSLYILRAQ 116 Query: 659 AIDG----GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 ID P+S VI ++ D+ND+ P F + + E SP GT + ++ A+D Sbjct: 117 VIDTTIGKAVEPESEFVI---RVSDVNDNEPRFLDEPYEAIVPEMSPEGTFVIKVTANDA 173 Query: 715 DE---GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA-- 769 D+ G +A + Y+++ G FS+E G + + + +D + + Y ++I+A Sbjct: 174 DDPTSGYHARILYNLEQGQPY--FSVEPTTGVIR--ISSKMDRELQDT---YCVIIQAKD 226 Query: 770 --ASP-PLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDADVTD 825 P L + I ++D+NDN P+ K+ F + P G G++ AYD D+ + Sbjct: 227 MLGQPGALSGTTTISIKLSDINDNKPIFKESFYRF-TISESAPSGTTIGKIMAYDDDIGE 285 Query: 826 --KLQYRILSGNNA--NLILLNET 845 ++ Y I + ++++ NET Sbjct: 286 NAEMDYSIEDDESQIFDIVIDNET 309 Score = 41.1 bits (92), Expect = 0.43 Identities = 20/44 (45%), Positives = 26/44 (59%), Gaps = 1/44 (2%) Query: 8 HQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD 51 H + VL+ NDH+P F Q YE V E A SG + T+ A D+D Sbjct: 453 HVYVQVLNINDHAPEFS-QLYETYVCENAESGEIIQTISAIDRD 495 >UniRef50_A4GJB0 Cluster: Hypothetical cadherin domain containing protein; n=1; uncultured marine bacterium EB0_49D07|Rep: Hypothetical cadherin domain containing protein - uncultured marine bacterium EB0_49D07 Length = 2204 Score = 166 bits (403), Expect = 9e-39 Identities = 169/603 (28%), Positives = 272/603 (45%), Gaps = 64/603 (10%) Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 D F ID SG + + LD E Y + V A D +ST I +++ D N+ Sbjct: 662 DNFSIDA-SGNITLASGLDYETATSYELTVVADDGT------YASTEVITISVADVNEAP 714 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 S + ++ + T IA +TD + GA I Y++ G ++ FS+ S G Sbjct: 715 TLSSTVAFNTFLENTATGT---TIATSSSTDPEAGA---ISYSLSGTGSE-NFSVSS-DG 766 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 V+L LDYE Y + + A DG + S S T L IN+ D+N+ AP SL + + Sbjct: 767 TVTLASALDYETTTEYAITLTASDGAN-SVSET--LTINVGDINE-APSLTNSLAASTFA 822 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 ENV G +I A D + + +TY+++ TG+ + + +G + S LD E Sbjct: 823 ENVSTGTTIATASASDPE---SQAITYSLSG---TGSENFAVD---SAGNITLSSALDYE 873 Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387 T Y L +TA+DG + +T+ + + L+E GT V T Sbjct: 874 TTTSYSLTLTASDGAN----STSNTINISVDDVTELSIALASS-SISLSEAATSGTSVTT 928 Query: 388 LTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447 TAT D + Y ++G ++ +FS++S G IT A LD++ Y LT++ATD G Sbjct: 929 -TATTTDGSATVTYSLSGTDS-DKFSVSSN---GTITTAASLDYETTTSYSLTLTATD-G 982 Query: 448 GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507 + T + INITD + N + E+ GT+++ SA+ G ++YS Sbjct: 983 TNTVTDSLTINITDVDL---TVTNTLAASGQAENISTGTSIMTASAS----GAEGTMSYS 1035 Query: 508 LSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDV 567 ++ D +F IN TG +T LD ET + + TVTA D GV ++ T + Sbjct: 1036 ITDS---------DNKFSINSSTGEVTLANALDYETKTSHTFTVTATD-GVTTV--TEEF 1083 Query: 568 EISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREE 627 +SV D+ N A + E + GTSV ++ D + + Y L Sbjct: 1084 TLSVTDMIINTLAVSLANSGAALAESSSSGTSVGSSSISNPD---SETVSYSL--SGTGS 1138 Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVF 687 +F +D +SG + TN LD E+ ++ L A GG + + +E++ + + Sbjct: 1139 SNFAVD-SSGNVTTNATLDFETAKSYSLTLTATAGGNTTTDAFTVNVGNVEELESAVLRY 1197 Query: 688 ESD 690 +D Sbjct: 1198 SAD 1200 Score = 147 bits (356), Expect = 4e-33 Identities = 170/603 (28%), Positives = 275/603 (45%), Gaps = 72/603 (11%) Query: 157 VSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLD 216 V+V E +V V+A ATD + +A+ Y++ G T + S +G+V+L LD Sbjct: 531 VNVSE--TVPAGTVVATFSATDPE---GNALTYSL--GGTGSELMTVSETGEVTLTGNLD 583 Query: 217 YEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAP-RFYTSLFQESVSENVPIGYS 275 +E + +V+ DG +NTT I I +ND+ P +L S +E +G + Sbjct: 584 FETNSTLVMVLEVSDG-----TNTTIEEITINVINDDEPATIAATLSAASFAETSAVGAA 638 Query: 276 IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLL 335 I + A D + + + Y+++ TG+ + I SG + + LD ET Y+L Sbjct: 639 IASINATDPE---GSAMNYSLSG---TGSDNFSI---DASGNITLASGLDYETATSYELT 689 Query: 336 VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395 V A DG ++T + L E+ GT + T ++TD E Sbjct: 690 VVADDG---TYASTEVITISVADVNEAPTLSSTVAFNTFL-ENTATGTTIATSSSTD-PE 744 Query: 396 DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMV 455 + Y ++G + FS++S G +T+A LD++ Y +T++A+D G S + + Sbjct: 745 AGAISYSLSGTGSE-NFSVSSD---GTVTLASALDYETTTEYAITLTASD-GANSVSETL 799 Query: 456 QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515 IN+ D N AP N+ ++ E+ GTT+ SA+D + + ITYSLS S Sbjct: 800 TINVGDINE-APSLTNSLAASTFAENVSTGTTIATASASDPE---SQAITYSLSGTGS-- 853 Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575 + F ++ G IT + LD ET + Y LT+TA D G S S+T + ISV DV Sbjct: 854 ------ENFAVD-SAGNITLSSALDYETTTSYSLTLTASD-GANSTSNT--INISVDDVT 903 Query: 576 DNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPA 635 + + ++ E A GTSV+ AT D + + Y L D ++ S + Sbjct: 904 ELSIALASS--SISLSEAATSGTSVTTT-ATTTDG--SATVTYSLSGTDSDKFSV---SS 955 Query: 636 SGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695 +G I T +LD E+ ++ L A D GT + ++ ++I D+ + + S Sbjct: 956 NGTITTAASLDYETTTSYSLTLTATD-GTNTVTDSLTINITDVDLTVTNTLAASG----- 1009 Query: 696 ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLD 755 +EN GT+I A G + YSI D N FS+ + G E+ LD Sbjct: 1010 QAENISTGTSIMTASA----SGAEGTMSYSIT--DSDNKFSINSSTG----EVTLANALD 1059 Query: 756 YES 758 YE+ Sbjct: 1060 YET 1062 Score = 128 bits (309), Expect = 2e-27 Identities = 163/660 (24%), Positives = 277/660 (41%), Gaps = 75/660 (11%) Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 D +N T QE+ E PI + + + + + +++ T G + Sbjct: 386 DSTENVTEEVTETTQETTVEVAPI-FEVEASEVVENVDENTTDISLTQFAIVNPGEQNYT 444 Query: 309 ITIDPRSGWVYTSGQ----------LDRETQAKYQLLVT-ATDGGDPPRSATATXXXXXX 357 +TI+ +T Q LD E+Q +L VT +D GD A A Sbjct: 445 VTIEGEGSEAFTYNQETNSLEVIQELDHESQESVELTVTFVSDNGDTQELALALDVTDVD 504 Query: 358 XXX--------XXXXXFMPGQY---EVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG 406 + G+ +V ++E P GT V T +ATD E N L Y + G Sbjct: 505 EAVVLAVEPVNTISEVAISGELIANQVNVSETVPAGTVVATFSATD-PEGNALTYSL--G 561 Query: 407 NTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYA 466 T S+ G +T+ LDF+ V+ + +D ++T + +I I N+ Sbjct: 562 GTGSELMTVSETGE--VTLTGNLDFETNSTLVMVLEVSDG---TNTTIEEITINVINDDE 616 Query: 467 PVFENAPYTASVF-EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFV 525 P A +A+ F E + +G + ++ATD + + + YSLS S+ F Sbjct: 617 PATIAATLSAASFAETSAVGAAIASINATDPE---GSAMNYSLSGTGSD--------NFS 665 Query: 526 INPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQL 585 I+ +G IT LD ET + Y LTV A DG + + T + ISV DVN+ P + Sbjct: 666 ID-ASGNITLASGLDYETATSYELTVVADDG---TYASTEVITISVADVNE-APTLSSTV 720 Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645 +E+ GT+++ +TD + G I Y L E S D G + AL Sbjct: 721 AFNTFLENTATGTTIATSSSTDPEA---GAISYSLSGTGSENFSVSSD---GTVTLASAL 774 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 D E+ + + A DG S + + I + DIN++P + S + + +EN GTT Sbjct: 775 DYETTTEYAITLTASDGA---NSVSETLTINVGDINEAPSLTNSLAASTF-AENVSTGTT 830 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYE 764 I A DP+ + + YS+ G S +F++ D A +T+ LDYE+ Y Sbjct: 831 IATASASDPE---SQAITYSL-SGTGSENFAV------DSAGNITLSSALDYET-TTSYS 879 Query: 765 LVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVT 824 L + A+ + I V DV + + + I + + G A D + Sbjct: 880 LTLTASDGANSTSNTINISVDDVTELSIALASSSI---SLSEAATSGTSVTTTATTTDGS 936 Query: 825 DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSV 884 + Y LSG +++ ++ + G++T + L+ ++ ++ TDG N + + +++ Sbjct: 937 ATVTYS-LSGTDSDKFSVS-SNGTITTAASLDYETTTSYSLTLTATDGTNTVTDSLTINI 994 Score = 117 bits (281), Expect = 5e-24 Identities = 136/546 (24%), Positives = 243/546 (44%), Gaps = 60/546 (10%) Query: 374 ELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQ 433 E+ E+ T ++LT +Y +T G + T + V Q LD + Sbjct: 416 EVVENVDENTTDISLTQFAIVNPGEQNYTVTIEG-EGSEAFTYNQETNSLEVIQELDHES 474 Query: 434 ERRYVLTVSATDSGGRSDTAMVQINITDA-----------NNYAPVFENAPYTAS---VF 479 + LTV+ G + + +++TD N + V + A+ V Sbjct: 475 QESVELTVTFVSDNGDTQELALALDVTDVDEAVVLAVEPVNTISEVAISGELIANQVNVS 534 Query: 480 EDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 E P GT V SATD + NA +TYSL S + + +TG +T L Sbjct: 535 ETVPAGTVVATFSATDPEG--NA-LTYSLGGTGS---------ELMTVSETGEVTLTGNL 582 Query: 540 DRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV-FKQQLYTANIMEDALVGT 598 D ET S ++ + DG ++TT EI++ +ND+EP L A+ E + VG Sbjct: 583 DFETNSTLVMVLEVSDG-----TNTTIEEITINVINDDEPATIAATLSAASFAETSAVGA 637 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAV 658 +++ + ATD + ++Y L + +F ID ASG I LD E+ +++L V Sbjct: 638 AIASINATDPE---GSAMNYSLSGTGSD--NFSID-ASGNITLASGLDYETATSYELTVV 691 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 A DG +ST ++ I + D+N++P + + ++ EN+ GTTI + DP+ G Sbjct: 692 ADDG---TYASTEVITISVADVNEAPTLSSTVAFNTFL-ENTATGTTIATSSSTDPEAG- 746 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVD-LDYESPRKKYELVIRAASPPLWND 777 + YS+ G N FS+ + G+ VT+ LDYE+ + Y + + A+ Sbjct: 747 --AISYSLSGTGSEN-FSVSS-DGT-----VTLASALDYETTTE-YAITLTASDGANSVS 796 Query: 778 VRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNA 837 + I V D+N+ AP + + + + + + G + + + Y + + Sbjct: 797 ETLTINVGDINE-APSLTN-SLAASTFAENVSTGTTIATASASDPESQAITYSLSGTGSE 854 Query: 838 NLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLITE-EMLLNSI 896 N + ++ G++TLS L+ ++ ++ +DG N + +SV +TE + L S Sbjct: 855 NFAV--DSAGNITLSSALDYETTTSYSLTLTASDGANSTSNTINISVDDVTELSIALASS 912 Query: 897 TVRLND 902 ++ L++ Sbjct: 913 SISLSE 918 >UniRef50_UPI000065CB52 Cluster: Homolog of Homo sapiens "Protocadherin 20; n=2; Clupeocephala|Rep: Homolog of Homo sapiens "Protocadherin 20 - Takifugu rubripes Length = 406 Score = 164 bits (399), Expect = 3e-38 Identities = 127/419 (30%), Positives = 192/419 (45%), Gaps = 24/419 (5%) Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268 V + LD E Y I A+DGG+P L I I DVNDN P+F S ++ Sbjct: 5 VIVTDALDRETQAEYITDIIAEDGGTPPLLGAATLKIVIADVNDNCPQFTESQINVTLHG 64 Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328 N G + R+ A+D D G NA+++Y +++ L +D +G + + + D T Sbjct: 65 NASKGTHLARLHAFDPDLGANAQISYAYSERVPKDTRSL-FHLDRITGVIKLARKTDTGT 123 Query: 329 QAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTL 388 Y+L V A G P AT F ++ + E+ P T + L Sbjct: 124 ATFYKLTVLANGPGCIPAVAT----IHVLDENDNAPVFEKSLVKISIDENNSPNTFLAQL 179 Query: 389 TATDADEDNRLH-YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447 ATD D + R + GG+ F + G++ VA LD +++ Y V A D G Sbjct: 180 QATDQDSEGRGEVIYLLGGDAPEIFIL--DRVTGVLIVAASLDREEKETYRFIVRAVDQG 237 Query: 448 --GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505 R A V + + D N+ +P F N +T V E+ P + V+S TD+D G N + Sbjct: 238 TPRRESIATVVLTVQDRNDNSPRFLNKDFTFFVPENFPGYGEIGVISVTDADAGENGWVA 297 Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTT 565 S + + F+I+ G + LDRE Y L + A DGG P+LS T Sbjct: 298 LS---------IINGSDTFMIDTGRGTLRAKTSLDREQQGTYQLWIEAADGGEPALSCIT 348 Query: 566 DVEISVVDVNDNEP--VFKQ--QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620 + + ++DVNDN P +F Q Q Y ++ + L GTS+++V A D D G+N I Y + Sbjct: 349 MITVLLLDVNDNPPTVLFPQSNQSYML-VLPNTLPGTSITEVYAVDRDTGMNAVIAYSI 406 Score = 164 bits (398), Expect = 4e-38 Identities = 128/418 (30%), Positives = 187/418 (44%), Gaps = 23/418 (5%) Query: 317 WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376 +V + LDRETQA+Y + A DGG PP AT F Q V L Sbjct: 4 FVIVTDALDRETQAEYITDIIAEDGGTPPLLGAATLKIVIADVNDNCPQFTESQINVTLH 63 Query: 377 EDEPPGTPVVTLTATDAD--EDNRLHY---EITGGNTRGRFSITSQNGRGLITVAQPLDF 431 + GT + L A D D + ++ Y E +TR F + G+I +A+ D Sbjct: 64 GNASKGTHLARLHAFDPDLGANAQISYAYSERVPKDTRSLFHL--DRITGVIKLARKTDT 121 Query: 432 KQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491 Y LTV A G A+ I++ D N+ APVFE + S+ E+ T + + Sbjct: 122 GTATFYKLTVLANGPG--CIPAVATIHVLDENDNAPVFEKSLVKISIDENNSPNTFLAQL 179 Query: 492 SATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTV 551 ATD D ++ Y L + + F+++ TG + LDRE Y V Sbjct: 180 QATDQDSEGRGEVIYLLGGDA--------PEIFILDRVTGVLIVAASLDREEKETYRFIV 231 Query: 552 TARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG 611 A D G P V ++V D NDN P F + +T + E+ + + TDAD G Sbjct: 232 RAVDQGTPRRESIATVVLTVQDRNDNSPRFLNKDFTFFVPENFPGYGEIGVISVTDADAG 291 Query: 612 LNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTV 671 NG + + +F+ID G +R +LDRE T+ L A DGG P S Sbjct: 292 ENGWVALSI---INGSDTFMIDTGRGTLRAKTSLDREQQGTYQLWIEAADGGEPALSCIT 348 Query: 672 IVHIKIEDINDSPPVF---ESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 ++ + + D+ND+PP +S+ + N+ GT+I E+ A D D G NAV+ YSI Sbjct: 349 MITVLLLDVNDNPPTVLFPQSNQSYMLVLPNTLPGTSITEVYAVDRDTGMNAVIAYSI 406 Score = 158 bits (384), Expect = 2e-36 Identities = 121/378 (32%), Positives = 186/378 (49%), Gaps = 24/378 (6%) Query: 423 ITVAQPLDFKQERRYVLTVSATDSGGRS--DTAMVQINITDANNYAPVFENAPYTASVFE 480 + V LD + + Y+ + A D G A ++I I D N+ P F + ++ Sbjct: 5 VIVTDALDRETQAEYITDIIAEDGGTPPLLGAATLKIVIADVNDNCPQFTESQINVTLHG 64 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 +A GT + + A D D+G NAQI+Y+ S + + + F ++ TG I + D Sbjct: 65 NASKGTHLARLHAFDPDLGANAQISYAYSERVPKDTRS----LFHLDRITGVIKLARKTD 120 Query: 541 RETMSGYLLTVTARDGG-VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTS 599 T + Y LTV A G +P+++ I V+D NDN PVF++ L +I E+ T Sbjct: 121 TGTATFYKLTVLANGPGCIPAVAT-----IHVLDENDNAPVFEKSLVKISIDENNSPNTF 175 Query: 600 VSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA 659 ++Q+ ATD D G + Y L E F++D +GV+ +LDRE T+ A Sbjct: 176 LAQLQATDQDSEGRGEVIYLLGGDAPE--IFILDRVTGVLIVAASLDREEKETYRFIVRA 233 Query: 660 IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 +D GTP + S V + ++D ND+ P F + TF++ EN P IG I D D G N Sbjct: 234 VDQGTPRRESIATVVLTVQDRNDNSPRFLNKDFTFFVPENFPGYGEIGVISVTDADAGEN 293 Query: 720 AVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWN 776 V SI G D +F ++T +G+ +A+ LD E + Y+L I AA P L Sbjct: 294 GWVALSIINGSD--TFMIDTGRGTLRAK----TSLDREQ-QGTYQLWIEAADGGEPALSC 346 Query: 777 DVRVEILVTDVNDNAPVM 794 + +L+ DVNDN P + Sbjct: 347 ITMITVLLLDVNDNPPTV 364 Score = 149 bits (362), Expect = 8e-34 Identities = 106/340 (31%), Positives = 163/340 (47%), Gaps = 36/340 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTI-ELVTAD 68 +I + D ND+ P F Q ++ AS GT + L A D D+G NA++ Y E V D Sbjct: 40 KIVIADVNDNCPQFTESQINVTLHGNASKGTHLARLHAFDPDLGANAQISYAYSERVPKD 99 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSD 128 T + +F +D +G + D Y + V A Sbjct: 100 T-----------------RSLFHLDRITGVIKLARKTDTGTATFYKLTVLANGPGC---- 138 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 + + ATIHV +D+NDN P F + +S+DE+ S N +A+++ATD D + Sbjct: 139 -IPAVATIHV--LDENDNAPVFEKSLVKISIDENNS--PNTFLAQLQATDQDSEGRGEVI 193 Query: 189 YAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIR 248 Y ++GG+ F +D ++G + + +LD E+ +YR ++RA D G+P R + +++ ++ Sbjct: 194 Y-LLGGDAPEIFILDRVTGVLIVAASLDREEKETYRFIVRAVDQGTPRRESIATVVLTVQ 252 Query: 249 DVNDNAPRFYTSLFQESVSENVPIGYSIVRV-QAYDADEGVNAELTYTMTDKDYTGNVDL 307 D NDN+PRF F V EN P GY + V DAD G N + ++ + T Sbjct: 253 DRNDNSPRFLNKDFTFFVPENFP-GYGEIGVISVTDADAGENGWVALSIINGSDT----- 306 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRS 347 ID G + LDRE Q YQL + A DGG+P S Sbjct: 307 -FMIDTGRGTLRAKTSLDREQQGTYQLWIEAADGGEPALS 345 Score = 149 bits (360), Expect = 1e-33 Identities = 120/414 (28%), Positives = 185/414 (44%), Gaps = 26/414 (6%) Query: 104 SLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDI 163 +LDRE A Y + A D +P L AT+ + I D NDN PQF+E V++ + Sbjct: 10 ALDRETQAEYITDIIAEDGGTPP---LLGAATLKIVIADVNDNCPQFTESQINVTLHGNA 66 Query: 164 SVTDNPVIAKIKATDADVGANSAIRYAI---IGGNTQMQFSIDSLSGDVSLVKTLDYEQV 220 S + +A++ A D D+GAN+ I YA + +T+ F +D ++G + L + D Sbjct: 67 SKGTH--LARLHAFDPDLGANAQISYAYSERVPKDTRSLFHLDRITGVIKLARKTDTGTA 124 Query: 221 RSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQ 280 Y+L + A G T I++ D NDNAP F SL + S+ EN + ++Q Sbjct: 125 TFYKLTVLANGPGCIPAVAT----IHVLDENDNAPVFEKSLVKISIDENNSPNTFLAQLQ 180 Query: 281 AYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD 340 A D D E+ Y + G+ +D +G + + LDRE + Y+ +V A D Sbjct: 181 ATDQDSEGRGEVIYLL-----GGDAPEIFILDRVTGVLIVAASLDREEKETYRFIVRAVD 235 Query: 341 GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH 400 G P R + AT F+ + + E+ P + ++ TDAD Sbjct: 236 QGTPRRESIATVVLTVQDRNDNSPRFLNKDFTFFVPENFPGYGEIGVISVTDADAGENGW 295 Query: 401 YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG--GRSDTAMVQIN 458 ++ N F I GRG + LD +Q+ Y L + A D G S M+ + Sbjct: 296 VALSIINGSDTFMI--DTGRGTLRAKTSLDREQQGTYQLWIEAADGGEPALSCITMITVL 353 Query: 459 ITDANNYAPVF----ENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSL 508 + D N+ P N Y + P GT++ V A D D G+NA I YS+ Sbjct: 354 LLDVNDNPPTVLFPQSNQSYMLVLPNTLP-GTSITEVYAVDRDTGMNAVIAYSI 406 Score = 143 bits (347), Expect = 5e-32 Identities = 109/292 (37%), Positives = 148/292 (50%), Gaps = 36/292 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I+VLD ND++PVFE + S+ E S T + L+ATDQD EV Y L+ D Sbjct: 145 IHVLDENDNAPVFEKSLVKISIDENNSPNTFLAQLQATDQDSEGRGEVIY---LLGGDA- 200 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 PE +F +D +G L+ ASLDRE+ Y +V+A DQ +P R Sbjct: 201 -PE---------------IFILDRVTGVLIVAASLDREEKETYRFIVRAVDQGTP---RR 241 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 S AT+ + + D NDN P+F K +T V E+ I I TDAD G N + + Sbjct: 242 ESIATVVLTVQDRNDNSPRFLNKDFTFFVPENFPGYGE--IGVISVTDADAGENGWVALS 299 Query: 191 IIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDV 250 II G+ F ID+ G + +LD EQ +Y+L I A DGG P+ S T + + + DV Sbjct: 300 IINGSDT--FMIDTGRGTLRAKTSLDREQQGTYQLWIEAADGGEPALSCITMITVLLLDV 357 Query: 251 NDNAPRFYTSLFQES------VSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 NDN P T LF +S V N G SI V A D D G+NA + Y++ Sbjct: 358 NDNPP---TVLFPQSNQSYMLVLPNTLPGTSITEVYAVDRDTGMNAVIAYSI 406 Score = 124 bits (298), Expect = 5e-26 Identities = 100/353 (28%), Positives = 160/353 (45%), Gaps = 25/353 (7%) Query: 530 TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN 589 T + LDRET + Y+ + A DGG P L ++I + DVNDN P F + Sbjct: 2 TPFVIVTDALDRETQAEYITDIIAEDGGTPPLLGAATLKIVIADVNDNCPQFTESQINVT 61 Query: 590 IMEDALVGTSVSQVGATDADVGLNGRIHY---ELDPKDREEGSFVIDPASGVIRTNKALD 646 + +A GT ++++ A D D+G N +I Y E PKD F +D +GVI+ + D Sbjct: 62 LHGNASKGTHLARLHAFDPDLGANAQISYAYSERVPKD-TRSLFHLDRITGVIKLARKTD 120 Query: 647 RESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706 + + L +A G P +T I + D ND+ PVFE + I EN+ T + Sbjct: 121 TGTATFYKLTVLANGPGCIPAVAT----IHVLDENDNAPVFEKSLVKISIDENNSPNTFL 176 Query: 707 GEIRAHDPD-EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765 +++A D D EG V++ + GGD F L+ G L+ LD E ++ Y Sbjct: 177 AQLQATDQDSEGRGEVIY--LLGGDAPEIFILDRVTG----VLIVAASLDREE-KETYRF 229 Query: 766 VIRA---ASPPLWNDVRVEILVTDVNDNAP--VMKDFQIIFNNYKDCFP-VGPFGRVPAY 819 ++RA +P + V + V D NDN+P + KDF + FP G G + Sbjct: 230 IVRAVDQGTPRRESIATVVLTVQDRNDNSPRFLNKDFTFF---VPENFPGYGEIGVISVT 286 Query: 820 DADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 DAD + + N ++ +++ G++ L+ + + DG Sbjct: 287 DADAGENGWVALSIINGSDTFMIDTGRGTLRAKTSLDREQQGTYQLWIEAADG 339 >UniRef50_Q4RZD6 Cluster: Chromosome undetermined SCAF14942, whole genome shotgun sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome undetermined SCAF14942, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 630 Score = 163 bits (397), Expect = 5e-38 Identities = 157/551 (28%), Positives = 245/551 (44%), Gaps = 51/551 (9%) Query: 521 DQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580 + +F+I+ TG I + LDRE + + V A D G L+ TDV I+V D+NDNEPV Sbjct: 2 ESEFIIDEVTGKIYAQRTLDREERAVWRFVVLATDEGGEGLTGFTDVIINVWDINDNEPV 61 Query: 581 FK-QQLYTANIMEDALVGTSVSQVGATDAD---VGLNGRIHYEL-------DPKDREEGS 629 F ++ E++LVGTSV ++ ATD D VG N + Y + + DR S Sbjct: 62 FTCAPSCHGSVAENSLVGTSVMEMTATDLDDSAVGQNAVLSYRIMGSLDGANFHDRGVPS 121 Query: 630 ----FVIDPASGVIRTN-KALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSP 684 F I+P++G I + LDRE V ++ + A DGG +T + IK D+ND Sbjct: 122 SSEMFTINPSTGTISVAMEGLDREQVESYLIFVEARDGGGLAGIATATIQIK--DLNDHA 179 Query: 685 PVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSD 744 P F D ISEN+ + E+ A D D G NA + +S+ GD F + + + Sbjct: 180 PKFTDDTCAVQISENTETNAEVLELAAEDRDIGENAQLTFSVVAGDQEQKFYIVSHKQEQ 239 Query: 745 KAELVTMVDLDYE-SPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNN 803 + L LDYE +++ L ++ L + L T + K+F I Sbjct: 240 RGTLRLKKKLDYERHGEQRFNLTLK---DNLNGTATLTALRTFDRER---QKEFFIPV-- 291 Query: 804 YKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLA 863 P G+V + D D D Y + GN N +LN+ TG + + NT P Sbjct: 292 IMSRLPTTVIGKVFSPDPDEWDNKTY-VFEGNVPNYFVLNKRTGFLIIKE--NT-PPGTY 347 Query: 864 TMEVSVTDGV-NEIKAMMQLSVRLITEEMLLNSITVRLNDMTAEQFLSPLLG------FF 916 +V V D V + + + + VR + +E + NS ++RL D+TA +F+ G Sbjct: 348 QFQVRVADDVWPDAVSSVSVHVRELRDEAIYNSGSLRLADITAREFIELRRGQRSRYDLL 407 Query: 917 IDGLAAIIPCPKENIYIFSVQDDTDVTGNILNVSFSARRPDAEVGVAGDPSPHYSPTHLR 976 D L+ ++ P ++ IFS+ TDV +L+V F+ R VG S P + Sbjct: 408 GDFLSEMLSVPPNDVNIFSL---TDVKDRMLDVRFAVR-----VG-----SSFLQPEKMH 454 Query: 977 ERVYLHRTTLARLATVQVLPFDDNICVHEPCLNFEECLTVLKFGNASGFVNSDSVLFRPI 1036 + H+ L + V + C C C VL + V+ ++ + Sbjct: 455 GYLAAHKQKLQSFLQIVVFQIRVDECPSSGCAGASGCTNVLNVRDTPMVVDCGTMSLVSV 514 Query: 1037 YPVTSFTCQCP 1047 ++ C CP Sbjct: 515 TLESTAVCSCP 525 Score = 100 bits (239), Expect = 7e-19 Identities = 81/278 (29%), Positives = 137/278 (49%), Gaps = 23/278 (8%) Query: 197 QMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPR 256 + +F ID ++G + +TLD E+ +R V+ A D G + T ++IN+ D+NDN P Sbjct: 2 ESEFIIDEVTGKIYAQRTLDREERAVWRFVVLATDEGGEGLTGFTDVIINVWDINDNEPV 61 Query: 257 FYTS-LFQESVSENVPIGYSIVRVQAYDADE---GVNAELTYTMT---------DKDYTG 303 F + SV+EN +G S++ + A D D+ G NA L+Y + D+ Sbjct: 62 FTCAPSCHGSVAENSLVGTSVMEMTATDLDDSAVGQNAVLSYRIMGSLDGANFHDRGVPS 121 Query: 304 NVDLPITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 + ++ TI+P +G + + + LDRE Y + V A DGG ATAT Sbjct: 122 SSEM-FTINPSTGTISVAMEGLDREQVESYLIFVEARDGGGLAGIATAT--IQIKDLNDH 178 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITS--QN 418 F V+++E+ V+ L A D D E+ +L + + G+ +F I S Q Sbjct: 179 APKFTDDTCAVQISENTETNAEVLELAAEDRDIGENAQLTFSVVAGDQEQKFYIVSHKQE 238 Query: 419 GRGLITVAQPLDFKQ--ERRYVLTVSATDSGGRSDTAM 454 RG + + + LD+++ E+R+ LT+ +G + TA+ Sbjct: 239 QRGTLRLKKKLDYERHGEQRFNLTLKDNLNGTATLTAL 276 Score = 96.3 bits (229), Expect = 1e-17 Identities = 79/278 (28%), Positives = 136/278 (48%), Gaps = 24/278 (8%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F ID +G + + +LDRE+ A + +V ATD+ + L+ + +N+ D NDN P Sbjct: 5 FIIDEVTGKIYAQRTLDREERAVWRFVVLATDEG---GEGLTGFTDVIINVWDINDNEPV 61 Query: 150 FS-EKTYTVSVDEDISVTDNPVIAKIKATDAD---VGANSAIRYAIIGG----------- 194 F+ + SV E+ V + + ++ ATD D VG N+ + Y I+G Sbjct: 62 FTCAPSCHGSVAENSLVGTS--VMEMTATDLDDSAVGQNAVLSYRIMGSLDGANFHDRGV 119 Query: 195 -NTQMQFSIDSLSGDVSL-VKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVND 252 ++ F+I+ +G +S+ ++ LD EQV SY + + A+DGG + T I I+D+ND Sbjct: 120 PSSSEMFTINPSTGTISVAMEGLDREQVESYLIFVEARDGGGLAGIATA--TIQIKDLND 177 Query: 253 NAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITID 312 +AP+F +SEN ++ + A D D G NA+LT+++ D + Sbjct: 178 HAPKFTDDTCAVQISENTETNAEVLELAAEDRDIGENAQLTFSVVAGDQEQKFYIVSHKQ 237 Query: 313 PRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350 + G + +LD E + + +T D + + TA Sbjct: 238 EQRGTLRLKKKLDYERHGEQRFNLTLKDNLNGTATLTA 275 Score = 93.5 bits (222), Expect = 8e-17 Identities = 70/230 (30%), Positives = 114/230 (49%), Gaps = 23/230 (10%) Query: 11 INVLDCNDHSPVFEMQ-QYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVT 66 INV D ND+ PVF SV E + GT+V+ + ATD D +G+NA + Y I + + Sbjct: 50 INVWDINDNEPVFTCAPSCHGSVAENSLVGTSVMEMTATDLDDSAVGQNAVLSYRI-MGS 108 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLVKATDQASP 125 D N D ++F I+ +G + + LDRE+V Y + V+A D Sbjct: 109 LDGANFHDRGVPSSS------EMFTINPSTGTISVAMEGLDREQVESYLIFVEARDGGG- 161 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 L+ AT + I D ND+ P+F++ T V + E+ N + ++ A D D+G N+ Sbjct: 162 ----LAGIATATIQIKDLNDHAPKFTDDTCAVQISENTET--NAEVLELAAEDRDIGENA 215 Query: 186 AIRYAIIGGNTQMQFSIDS----LSGDVSLVKTLDYEQVRSYRLVIRAQD 231 + ++++ G+ + +F I S G + L K LDYE+ R + +D Sbjct: 216 QLTFSVVAGDQEQKFYIVSHKQEQRGTLRLKKKLDYERHGEQRFNLTLKD 265 Score = 85.0 bits (201), Expect = 3e-14 Identities = 98/385 (25%), Positives = 158/385 (41%), Gaps = 40/385 (10%) Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATD-GGDPPRSATATXXXXXXXXXXXXXXFMPG 369 ID +G +Y LDRE +A ++ +V ATD GG+ T Sbjct: 7 IDEVTGKIYAQRTLDREERAVWRFVVLATDEGGEGLTGFTDVIINVWDINDNEPVFTCAP 66 Query: 370 QYEVELAEDEPPGTPVVTLTATDADED----NR-LHYEITGGNTRGRFS----------I 414 +AE+ GT V+ +TATD D+ N L Y I G F Sbjct: 67 SCHGSVAENSLVGTSVMEMTATDLDDSAVGQNAVLSYRIMGSLDGANFHDRGVPSSSEMF 126 Query: 415 TSQNGRGLITVA-QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAP 473 T G I+VA + LD +Q Y++ V A D GG + A I I D N++AP F + Sbjct: 127 TINPSTGTISVAMEGLDREQVESYLIFVEARDGGGLAGIATATIQIKDLNDHAPKFTDDT 186 Query: 474 YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEA--VAHHDQQFVINPQTG 531 + E+ VL ++A D D+G NAQ+T+S+ + + + H Q+ Q G Sbjct: 187 CAVQISENTETNAEVLELAAEDRDIGENAQLTFSVVAGDQEQKFYIVSHKQE-----QRG 241 Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 + K LD E +T +D +L+ T ++ + D E +Q+ + ++ Sbjct: 242 TLRLKKKLDYERHGEQRFNLTLKD----NLNGT--ATLTALRTFDRE---RQKEFFIPVI 292 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVA 651 L T + +V + D D N +E FV++ +G + + Sbjct: 293 MSRLPTTVIGKVFSPDPDEWDNKTYVFE----GNVPNYFVLNKRTGFLIIK---ENTPPG 345 Query: 652 THDLKAVAIDGGTPPQSSTVIVHIK 676 T+ + D P S+V VH++ Sbjct: 346 TYQFQVRVADDVWPDAVSSVSVHVR 370 >UniRef50_P33151 Cluster: Cadherin-5 precursor; n=34; Tetrapoda|Rep: Cadherin-5 precursor - Homo sapiens (Human) Length = 784 Score = 163 bits (396), Expect = 6e-38 Identities = 164/550 (29%), Positives = 253/550 (46%), Gaps = 51/550 (9%) Query: 159 VDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYE 218 +DE+ + + + KIK++ V +A +Y + G F +D+ +GDV ++ LD E Sbjct: 56 IDEEKNTSLPHHVGKIKSS---VSRKNA-KYLLKGEYVGKVFRVDAETGDVFAIERLDRE 111 Query: 219 QVRSYRL--VIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSI 276 + Y L VI +D G + + I + DVNDN P F LF SV E+ +G S+ Sbjct: 112 NISEYHLTAVIVDKDTGE-NLETPSSFTIKVHDVNDNWPVFTHRLFNASVPESSAVGTSV 170 Query: 277 VRVQAYDADE---GVNAELTY-TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332 + V A DAD+ G +A + Y + K+Y ID + + LDRE QA+Y Sbjct: 171 ISVTAVDADDPTVGDHASVMYQILKGKEY-------FAIDNSGRIITITKSLDREKQARY 223 Query: 333 QLLVTATDG-GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTAT 391 +++V A D G S TAT F +Y + ED GT V +L Sbjct: 224 EIVVEARDAQGLRGDSGTATVLVTLQDINDNFPFFTQTKYTFVVPEDTRVGTSVGSLFVE 283 Query: 392 DADE-DNRL-HYEITGGNTRGRFSITSQ--NGRGLITVAQPLDFKQERRYVLTVSATD-- 445 D DE NR+ Y I G+ + F+I + + G+I +PLD++ ++Y V ATD Sbjct: 284 DPDEPQNRMTKYSILRGDYQDAFTIETNPAHNEGIIKPMKPLDYEYIQQYSFIVEATDPT 343 Query: 446 ------SGGRSDTAMVQINITDANNYAPVFENAPYTASVFED--APIGTTVLVVSATDSD 497 S + A V INITD + P+F+ Y + E+ P+ TVL A D D Sbjct: 344 IDLRYMSPPAGNRAQVIINITDVDE-PPIFQQPFYHFQLKENQKKPLIGTVL---AMDPD 399 Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD-- 555 ++ I YS+ S++ QF + G I K LDRE Y LTV A++ Sbjct: 400 AARHS-IGYSI-RRTSDKG------QFFRVTKKGDIYNEKELDREVYPWYNLTVEAKELD 451 Query: 556 -GGVPSLSDT-TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV-GL 612 G P+ ++ V I V+D NDN P F + Y + E+A+ G V Q+ A D D+ Sbjct: 452 STGTPTGKESIVQVHIEVLDENDNAPEFAKP-YQPKVCENAVHGQLVLQISAIDKDITPR 510 Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVI 672 N + + L+ ++ + D + + DRE H L V D G P ++ T Sbjct: 511 NVKFKFTLNTENNFTLTDNHDNTANITVKYGQFDREHTKVHFLPVVISDNGMPSRTGTST 570 Query: 673 VHIKIEDIND 682 + + + N+ Sbjct: 571 LTVAVCKCNE 580 Score = 160 bits (389), Expect = 4e-37 Identities = 134/507 (26%), Positives = 230/507 (45%), Gaps = 31/507 (6%) Query: 86 VQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDND 145 V VFR+D +G + LDRE ++ Y + D+ + + L + ++ + + D ND Sbjct: 89 VGKVFRVDAETGDVFAIERLDRENISEYHLTAVIVDKDT--GENLETPSSFTIKVHDVND 146 Query: 146 NYPQFSEKTYTVSVDEDISVTDNPV-IAKIKATDADVGANSAIRYAIIGGNTQMQFSIDS 204 N+P F+ + + SV E +V + + + + A D VG ++++ Y I+ G F+ID+ Sbjct: 147 NWPVFTHRLFNASVPESSAVGTSVISVTAVDADDPTVGDHASVMYQILKGKEY--FAIDN 204 Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDG-GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263 +++ K+LD E+ Y +V+ A+D G S T +L+ ++D+NDN P F + + Sbjct: 205 SGRIITITKSLDREKQARYEIVVEARDAQGLRGDSGTATVLVTLQDINDNFPFFTQTKYT 264 Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323 V E+ +G S+ + D DE N Y++ DY + G + Sbjct: 265 FVVPEDTRVGTSVGSLFVEDPDEPQNRMTKYSILRGDYQDAFTIETNPAHNEGIIKPMKP 324 Query: 324 LDRETQAKYQLLVTATDGG-----DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAED 378 LD E +Y +V ATD P + F Y +L E+ Sbjct: 325 LDYEYIQQYSFIVEATDPTIDLRYMSPPAGNRAQVIINITDVDEPPIFQQPFYHFQLKEN 384 Query: 379 EPPGTPVV-TLTATDAD-EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436 + P++ T+ A D D + + Y I + +G+F ++ +G I + LD + Sbjct: 385 QK--KPLIGTVLAMDPDAARHSIGYSIRRTSDKGQFFRVTK--KGDIYNEKELDREVYPW 440 Query: 437 YVLTVSATD---SG---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV 490 Y LTV A + +G G+ V I + D N+ AP F PY V E+A G VL Sbjct: 441 YNLTVEAKELDSTGTPTGKESIVQVHIEVLDENDNAPEFAK-PYQPKVCENAVHGQLVLQ 499 Query: 491 VSATDSDV-GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLL 549 +SA D D+ N + ++L++E + +HD I + G DRE + L Sbjct: 500 ISAIDKDITPRNVKFKFTLNTENNFTLTDNHDNTANITVKYGQ------FDREHTKVHFL 553 Query: 550 TVTARDGGVPSLSDTTDVEISVVDVND 576 V D G+PS + T+ + ++V N+ Sbjct: 554 PVVISDNGMPSRTGTSTLTVAVCKCNE 580 Score = 151 bits (365), Expect = 4e-34 Identities = 101/287 (35%), Positives = 154/287 (53%), Gaps = 21/287 (7%) Query: 524 FVINPQTGAITTNKLLDRETMSGYLLT--VTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581 F ++ +TG + + LDRE +S Y LT + +D G +L + I V DVNDN PVF Sbjct: 93 FRVDAETGDVFAIERLDRENISEYHLTAVIVDKDTG-ENLETPSSFTIKVHDVNDNWPVF 151 Query: 582 KQQLYTANIMEDALVGTSVSQVGATDAD---VGLNGRIHYELDPKDREEGSFVIDPASGV 638 +L+ A++ E + VGTSV V A DAD VG + + Y++ K +E F ID + + Sbjct: 152 THRLFNASVPESSAVGTSVISVTAVDADDPTVGDHASVMYQI-LKGKEY--FAIDNSGRI 208 Query: 639 IRTNKALDRESVATHDLKAVAIDG-GTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYIS 697 I K+LDRE A +++ A D G S T V + ++DIND+ P F TF + Sbjct: 209 ITITKSLDREKQARYEIVVEARDAQGLRGDSGTATVLVTLQDINDNFPFFTQTKYTFVVP 268 Query: 698 ENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE 757 E++ +GT++G + DPDE N + YSI GD ++F++ET ++ + M LDYE Sbjct: 269 EDTRVGTSVGSLFVEDPDEPQNRMTKYSILRGDYQDAFTIETNPAHNEGIIKPMKPLDYE 328 Query: 758 SPRKKYELVIRAA---------SPPLWNDVRVEILVTDVNDNAPVMK 795 ++Y ++ A SPP N +V I +TDV D P+ + Sbjct: 329 Y-IQQYSFIVEATDPTIDLRYMSPPAGNRAQVIINITDV-DEPPIFQ 373 Score = 128 bits (310), Expect = 2e-27 Identities = 132/474 (27%), Positives = 207/474 (43%), Gaps = 54/474 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVTA 67 I V D ND+ PVF + + ASV E ++ GT+V+++ A D D +G +A V Y I Sbjct: 139 IKVHDVNDNWPVFTHRLFNASVPESSAVGTSVISVTAVDADDPTVGDHASVMYQI----- 193 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 ++ F ID + SLDREK ARY ++V+A D Sbjct: 194 ----------------LKGKEYFAIDNSGRIITITKSLDREKQARYEIVVEARDAQGLRG 237 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAI 187 D S TAT+ V + D NDN+P F++ YT V ED V + + + D D N Sbjct: 238 D--SGTATVLVTLQDINDNFPFFTQTKYTFVVPEDTRVGTS--VGSLFVEDPDEPQNRMT 293 Query: 188 RYAIIGGNTQMQFSIDS----LSGDVSLVKTLDYEQVRSYRLVIRAQDGG------SPSR 237 +Y+I+ G+ Q F+I++ G + +K LDYE ++ Y ++ A D SP Sbjct: 294 KYSILRGDYQDAFTIETNPAHNEGIIKPMKPLDYEYIQQYSFIVEATDPTIDLRYMSPPA 353 Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297 N Q++INI DV D P F + + EN I V A D D + Y++ Sbjct: 354 GNRAQVIINITDV-DEPPIFQQPFYHFQLKENQKKPL-IGTVLAMDPD-AARHSIGYSIR 410 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD---GGDPPRSATATXXX 354 G +T + G +Y +LDRE Y L V A + G P + Sbjct: 411 RTSDKGQF-FRVT---KKGDIYNEKELDREVYPWYNLTVEAKELDSTGTPTGKESIVQVH 466 Query: 355 XXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR-LHYEITGGNTRGRFS 413 Y+ ++ E+ G V+ ++A D D R + ++ T NT F+ Sbjct: 467 IEVLDENDNAPEFAKPYQPKVCENAVHGQLVLQISAIDKDITPRNVKFKFT-LNTENNFT 525 Query: 414 IT-SQNGRGLITVAQ-PLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDAN 463 +T + + ITV D + + + L V +D+G R+ T+ + + + N Sbjct: 526 LTDNHDNTANITVKYGQFDREHTKVHFLPVVISDNGMPSRTGTSTLTVAVCKCN 579 Score = 119 bits (286), Expect = 1e-24 Identities = 124/442 (28%), Positives = 186/442 (42%), Gaps = 36/442 (8%) Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 +Y G V +D +G V+ +LDRE ++Y L D T + Sbjct: 87 EYVGKV---FRVDAETGDVFAIERLDRENISEYHLTAVIVDKDTGENLETPSSFTIKVHD 143 Query: 360 XXXXX-XFMPGQYEVELAEDEPPGTPVVTLTATDADEDN-RLHYEITGGNTRGRFSITSQ 417 F + + E GT V+++TA DAD+ H + +G+ Sbjct: 144 VNDNWPVFTHRLFNASVPESSAVGTSVISVTAVDADDPTVGDHASVMYQILKGKEYFAID 203 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGG-RSD--TAMVQINITDANNYAPVFENAPY 474 N +IT+ + LD +++ RY + V A D+ G R D TA V + + D N+ P F Y Sbjct: 204 NSGRIITITKSLDREKQARYEIVVEARDAQGLRGDSGTATVLVTLQDINDNFPFFTQTKY 263 Query: 475 TASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP--QTGA 532 T V ED +GT+V + D D N YS+ +A NP G Sbjct: 264 TFVVPEDTRVGTSVGSLFVEDPDEPQNRMTKYSILRGDYQDAFT-----IETNPAHNEGI 318 Query: 533 ITTNKLLDRETMSGYLLTVTARDGGV------PSLSDTTDVEISVVDVNDNEPVFKQQLY 586 I K LD E + Y V A D + P + V I++ DV D P+F+Q Y Sbjct: 319 IKPMKPLDYEYIQQYSFIVEATDPTIDLRYMSPPAGNRAQVIINITDV-DEPPIFQQPFY 377 Query: 587 TANIMEDA---LVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK 643 + E+ L+GT V A D D + I Y + + ++G F G I K Sbjct: 378 HFQLKENQKKPLIGT----VLAMDPDAARHS-IGYSIR-RTSDKGQFFRVTKKGDIYNEK 431 Query: 644 ALDRESVATHDL--KAVAIDG-GTPPQSSTVI-VHIKIEDINDSPPVFESDCLTFYISEN 699 LDRE ++L +A +D GTP +++ VHI++ D ND+ P F + EN Sbjct: 432 ELDREVYPWYNLTVEAKELDSTGTPTGKESIVQVHIEVLDENDNAPEFAKPYQP-KVCEN 490 Query: 700 SPIGTTIGEIRAHDPDEGPNAV 721 + G + +I A D D P V Sbjct: 491 AVHGQLVLQISAIDKDITPRNV 512 >UniRef50_UPI0000F1E792 Cluster: PREDICTED: hypothetical protein; n=2; Danio rerio|Rep: PREDICTED: hypothetical protein - Danio rerio Length = 826 Score = 163 bits (395), Expect = 8e-38 Identities = 176/630 (27%), Positives = 282/630 (44%), Gaps = 70/630 (11%) Query: 96 SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155 SG L LDREK Y++ V T + + T+ V +ID NDN P F E++ Sbjct: 69 SGFLYALKPLDREKQPSYSLQVSFTKSMH------TQSFTVEVCVIDKNDNVPVFLEESM 122 Query: 156 TVSVDEDISVTDNPVIAKIKATDADVG--ANSAIRYAIIGGNTQM----QFSIDSLSGDV 209 SV + + +++A D D A++ +R++++ ++ FSIDS++G+V Sbjct: 123 RGSVQ--LGLLKGIPFMQVEALDRDDRNTAHADLRFSLLDQIPRIPASHMFSIDSITGEV 180 Query: 210 SLVK----TLDYEQVRSYRLVIRAQD--GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ 263 SL + TLD E Y+L + QD G + + +T +L+ +V NA + S Sbjct: 181 SLTEDGASTLDPEMCGRYKLSVMVQDMAGKANAFFSTGTVLV---EVTGNA---WASPDP 234 Query: 264 ESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ 323 + EN+P Y I Q + V L + +T N R G +Y + Sbjct: 235 VRLQENLPGPYPIPISQVKWSGSPVEYSLEGEFPEMLFTIN---------REGIIYLNAP 285 Query: 324 LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGT 383 LDRETQ ++ + + + F QY + E GT Sbjct: 286 LDRETQDQFHIDIVVERPDGREIAKPVELRVMVGDANDNRPTFPQMQYHTVVKELATKGT 345 Query: 384 PVVTLTATDADE---DN-RLHYEITGG---NTRGRFSITSQNGRGLITVAQPLDFKQERR 436 ++T+ A D D+ DN R+ Y + G R F + +G +ITV + Sbjct: 346 EILTVQAADNDDPKTDNVRIFYRLVGQMPETPRNLFRVDRDSG--VITVQADSMEGTAPQ 403 Query: 437 YVLTVSATDSGGRSDT-------AMVQINITDANNYAPVFENAPYTA-SVFEDAPIGTTV 488 Y LT++A D+ GR +T V + + D NN P+F + Y + ED+ +GTTV Sbjct: 404 YTLTITAEDAKGRHNTDQWLNSSCTVIVKVLDENNNPPIFSHLEYGPFHLAEDSSVGTTV 463 Query: 489 LVVSATDSDV--GINAQITYSLSSEISNEAVAH-HDQQFVINPQTGAITTNKLLDRETMS 545 VVSA D+D G + Q+ Y L S E +D+Q A+ +K+LD E + Sbjct: 464 TVVSAWDADEWGGDSWQVDYRLESGNEEEVFTLLNDRQ----TNEAALILDKVLDFEREN 519 Query: 546 GYLLTVTARDG-----GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSV 600 Y+L ++A++ G + T V I + D+N+ PV Q Y + E G + Sbjct: 520 EYILVLSAQNPVALVRGRYGPASTATVTIFIDDINEG-PVLSQSHYEVTVREGEEPGRVI 578 Query: 601 SQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI 660 + + D D + I Y L + + F I SG ++T +ALDRE T+ ++ VA Sbjct: 579 ATIRGYDPD---SHPIRYSL--RGDTKRYFSIGKYSGELKTVQALDREENHTYTMEVVAE 633 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESD 690 DG S++ +V + I D+ND+ PV D Sbjct: 634 DGRNSSLSASTLVTVHILDVNDNSPVLVGD 663 Score = 136 bits (330), Expect = 6e-30 Identities = 170/631 (26%), Positives = 272/631 (43%), Gaps = 55/631 (8%) Query: 192 IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVN 251 + G+ + F ++S G + +K LD E+ SY L + ++S T ++ + D N Sbjct: 57 VNGDDEGIFGVES--GFLYALKPLDREKQPSYSLQVSFTKS-MHTQSFTVEVCVI--DKN 111 Query: 252 DNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG--VNAELTYTMTDKDYTGNVDLPI 309 DN P F + SV + G ++V+A D D+ +A+L +++ D+ Sbjct: 112 DNVPVFLEESMRGSVQLGLLKGIPFMQVEALDRDDRNTAHADLRFSLLDQIPRIPASHMF 171 Query: 310 TIDPRSGWVYTS----GQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX 365 +ID +G V + LD E +Y+L V D + +T Sbjct: 172 SIDSITGEVSLTEDGASTLDPEMCGRYKLSVMVQDMAGKANAFFSTGTVLVEVTGNAWAS 231 Query: 366 FMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITV 425 P V L E+ P P+ + + Y + G F+I N G+I + Sbjct: 232 PDP----VRLQENLPGPYPIPISQVKWSGSP--VEYSLEGEFPEMLFTI---NREGIIYL 282 Query: 426 AQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAP 483 PLD + + ++ + + GR V++ + DAN+ P F Y V E A Sbjct: 283 NAPLDRETQDQFHIDIVVERPDGREIAKPVELRVMVGDANDNRPTFPQMQYHTVVKELAT 342 Query: 484 IGTTVLVVSATDSD--VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 GT +L V A D+D N +I Y L ++ F ++ +G IT Sbjct: 343 KGTEILTVQAADNDDPKTDNVRIFYRLVGQMPETP----RNLFRVDRDSGVITVQADSME 398 Query: 542 ETMSGYLLTVTARDG-GVPS----LSDTTDVEISVVDVNDNEPVFKQQLYTA-NIMEDAL 595 T Y LT+TA D G + L+ + V + V+D N+N P+F Y ++ ED+ Sbjct: 399 GTAPQYTLTITAEDAKGRHNTDQWLNSSCTVIVKVLDENNNPPIFSHLEYGPFHLAEDSS 458 Query: 596 VGTSVSQVGATDADV--GLNGRIHYELDPKDREEGSFVIDPAS---GVIRTNKALD--RE 648 VGT+V+ V A DAD G + ++ Y L+ + EE +++ + +K LD RE Sbjct: 459 VGTTVTVVSAWDADEWGGDSWQVDYRLESGNEEEVFTLLNDRQTNEAALILDKVLDFERE 518 Query: 649 SVATHDLKA---VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 + L A VA+ G +ST V I I+DIN+ P + +S + E G Sbjct: 519 NEYILVLSAQNPVALVRGRYGPASTATVTIFIDDINEGPVLSQSH-YEVTVREGEEPGRV 577 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK-KYE 764 I IR +DPD P + YS++G D FS+ G EL T+ LD E E Sbjct: 578 IATIRGYDPDSHP---IRYSLRG-DTKRYFSI----GKYSGELKTVQALDREENHTYTME 629 Query: 765 LVIR-AASPPLWNDVRVEILVTDVNDNAPVM 794 +V + L V + + DVNDN+PV+ Sbjct: 630 VVAEDGRNSSLSASTLVTVHILDVNDNSPVL 660 Score = 132 bits (319), Expect = 1e-28 Identities = 153/592 (25%), Positives = 243/592 (41%), Gaps = 57/592 (9%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ V+D ND+ PVF + SV+ G G + ++A D+D A + L+ D Sbjct: 104 EVCVIDKNDNVPVFLEESMRGSVQLGLLKGIPFMQVEALDRDDRNTAHADLRFSLL--DQ 161 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + A + DG S +LD E RY + V D A ++ Sbjct: 162 IPRIPASHMFSIDSITGEVSLTEDGAS-------TLDPEMCGRYKLSVMVQDMAGK-ANA 213 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 ST T+ V + + P V + E++ I+++K + S + Y Sbjct: 214 FFSTGTVLVEVTGNAWASPD------PVRLQENLPGPYPIPISQVK------WSGSPVEY 261 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 ++ G +M F+I+ G + L LD E + + I + + +L + + D Sbjct: 262 SLEGEFPEMLFTINR-EGIIYLNAPLDRETQDQFHIDIVVERPDGREIAKPVELRVMVGD 320 Query: 250 VNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV--NAELTYTMTDKDYTGNVDL 307 NDN P F + V E G I+ VQA D D+ N + Y + + +L Sbjct: 321 ANDNRPTFPQMQYHTVVKELATKGTEILTVQAADNDDPKTDNVRIFYRLVGQMPETPRNL 380 Query: 308 PITIDPRSGWVYTSGQLDRETQAKYQLLVTATD-----GGDPPRSATATXXXXXXXXXXX 362 +D SG + T +Y L +TA D D +++ T Sbjct: 381 -FRVDRDSGVITVQADSMEGTAPQYTLTITAEDAKGRHNTDQWLNSSCTVIVKVLDENNN 439 Query: 363 XXXFMPGQY-EVELAEDEPPGTPVVTLTATDADE---DN-RLHYEITGGNTRGRFSITS- 416 F +Y LAED GT V ++A DADE D+ ++ Y + GN F++ + Sbjct: 440 PPIFSHLEYGPFHLAEDSSVGTTVTVVSAWDADEWGGDSWQVDYRLESGNEEEVFTLLND 499 Query: 417 -QNGRGLITVAQPLDFKQERRYVLTVSATD-------SGGRSDTAMVQINITDANNYAPV 468 Q + + + LDF++E Y+L +SA + G + TA V I I D N PV Sbjct: 500 RQTNEAALILDKVLDFERENEYILVLSAQNPVALVRGRYGPASTATVTIFIDDINE-GPV 558 Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528 + Y +V E G + + D D + I YSL + + F I Sbjct: 559 LSQSHYEVTVREGEEPGRVIATIRGYDPD---SHPIRYSLRGDTK--------RYFSIGK 607 Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580 +G + T + LDRE Y + V A DG SLS +T V + ++DVNDN PV Sbjct: 608 YSGELKTVQALDREENHTYTMEVVAEDGRNSSLSASTLVTVHILDVNDNSPV 659 Score = 117 bits (281), Expect = 5e-24 Identities = 155/627 (24%), Positives = 251/627 (40%), Gaps = 60/627 (9%) Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXX 355 +T D T N D SG++Y LDRE Q Y L V+ T + + T Sbjct: 50 LTYSDLTVNGDDEGIFGVESGFLYALKPLDREKQPSYSLQVSFTKS---MHTQSFTVEVC 106 Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGG--------N 407 F+ + G P + + A D D+ N H ++ Sbjct: 107 VIDKNDNVPVFLEESMRGSVQLGLLKGIPFMQVEALDRDDRNTAHADLRFSLLDQIPRIP 166 Query: 408 TRGRFSITSQNGRGLITV--AQPLDFKQERRYVLTVSATDSGGRSD----TAMVQINITD 461 FSI S G +T A LD + RY L+V D G+++ T V + +T Sbjct: 167 ASHMFSIDSITGEVSLTEDGASTLDPEMCGRYKLSVMVQDMAGKANAFFSTGTVLVEVT- 225 Query: 462 ANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521 N +A +P + E+ P G + +S + + YSL E + Sbjct: 226 GNAWA-----SPDPVRLQENLP-GPYPIPISQVKWS---GSPVEYSLEGEFP-------E 269 Query: 522 QQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581 F IN + G I N LDRET + + + ++ ++ + V D NDN P F Sbjct: 270 MLFTINRE-GIIYLNAPLDRETQDQFHIDIVVERPDGREIAKPVELRVMVGDANDNRPTF 328 Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGL--NGRIHYEL--DPKDREEGSFVIDPASG 637 Q Y + E A GT + V A D D N RI Y L + F +D SG Sbjct: 329 PQMQYHTVVKELATKGTEILTVQAADNDDPKTDNVRIFYRLVGQMPETPRNLFRVDRDSG 388 Query: 638 VIRTNKALDRESVATHDLKAVAIDGGTPPQS-----STVIVHIKIEDINDSPPVFES-DC 691 VI + + L A D + S+ V +K+ D N++PP+F + Sbjct: 389 VITVQADSMEGTAPQYTLTITAEDAKGRHNTDQWLNSSCTVIVKVLDENNNPPIFSHLEY 448 Query: 692 LTFYISENSPIGTTIGEIRAHDPDE--GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELV 749 F+++E+S +GTT+ + A D DE G + V Y ++ G++ F+L + +++A L+ Sbjct: 449 GPFHLAEDSSVGTTVTVVSAWDADEWGGDSWQVDYRLESGNEEEVFTLLNDRQTNEAALI 508 Query: 750 TMVDLDYESPRKKYELVIRAASPPLW--------NDVRVEILVTDVNDNAPVMKDFQIIF 801 LD+E +Y LV+ A +P + V I + D+N+ PV+ Sbjct: 509 LDKVLDFER-ENEYILVLSAQNPVALVRGRYGPASTATVTIFIDDINE-GPVLSQSHYEV 566 Query: 802 NNYKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPK 861 + P + YD D + ++Y L G+ + + +G + L+ Sbjct: 567 TVREGEEPGRVIATIRGYDPD-SHPIRYS-LRGDTKRYFSIGKYSGELKTVQALDREENH 624 Query: 862 LATMEVSVTDGVN-EIKAMMQLSVRLI 887 TMEV DG N + A ++V ++ Sbjct: 625 TYTMEVVAEDGRNSSLSASTLVTVHIL 651 Score = 108 bits (260), Expect = 2e-21 Identities = 101/357 (28%), Positives = 166/357 (46%), Gaps = 39/357 (10%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 + ++ V D ND+ P F QY V+E A+ GT +LT++A D D K V LV Sbjct: 312 VELRVMVGDANDNRPTFPQMQYHTVVKELATKGTEILTVQAADNDDPKTDNVRIFYRLVG 371 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATD-QASP 125 P +++FR+D SG + +A +YT+ + A D + Sbjct: 372 QMPETP--------------RNLFRVDRDSGVITVQADSMEGTAPQYTLTITAEDAKGRH 417 Query: 126 VSDR-LSSTATIHVNIIDDNDNYPQFSEKTY-TVSVDEDISVTDNPVIAKIKATDADV-- 181 +D+ L+S+ T+ V ++D+N+N P FS Y + ED SV + + A DAD Sbjct: 418 NTDQWLNSSCTVIVKVLDENNNPPIFSHLEYGPFHLAEDSSV--GTTVTVVSAWDADEWG 475 Query: 182 GANSAIRYAIIGGNTQMQFSI--DSLSGDVSLV--KTLDYEQVRSYRLVIRAQD-----G 232 G + + Y + GN + F++ D + + +L+ K LD+E+ Y LV+ AQ+ Sbjct: 476 GDSWQVDYRLESGNEEEVFTLLNDRQTNEAALILDKVLDFERENEYILVLSAQNPVALVR 535 Query: 233 GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAEL 292 G ++T + I I D+N+ P S ++ +V E G I ++ YD D + + Sbjct: 536 GRYGPASTATVTIFIDDINE-GPVLSQSHYEVTVREGEEPGRVIATIRGYDPD---SHPI 591 Query: 293 TYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSAT 349 Y++ G+ +I SG + T LDRE Y + V A DG + SA+ Sbjct: 592 RYSL-----RGDTKRYFSIGKYSGELKTVQALDREENHTYTMEVVAEDGRNSSLSAS 643 >UniRef50_Q0YH47 Cluster: Cadherin; n=1; Geobacter sp. FRC-32|Rep: Cadherin - Geobacter sp. FRC-32 Length = 1129 Score = 161 bits (392), Expect = 2e-37 Identities = 134/439 (30%), Positives = 203/439 (46%), Gaps = 42/439 (9%) Query: 366 FMP--GQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLI 423 FMP G Y V LAE+ GTPV ++ATDAD D + Y I GN G F+I + +G + Sbjct: 173 FMPNLGNYAVTLAENSAKGTPVGKVSATDADGDT-ITYTIIAGNDNGAFAIDAASGAITV 231 Query: 424 TVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 A LDF+ R + LTV A+D G SDT V IN+ D N+ APV + + +V E+AP Sbjct: 232 ADASKLDFEATREFTLTVQASD-GRLSDTGTVTINLVDRNDNAPVITSGS-SGTVAENAP 289 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 T + +A D+D ITYSL I+P +G +T N D ET Sbjct: 290 TDTVIYQAAARDADT--ETTITYSLKP-------GEDTSLLTIDPGSGTVTLNNSADFET 340 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 + Y TV A DG S V +SV+++NDN P+ ++ E+A + T + Q Sbjct: 341 KTSYTFTVIAGDG---VNSSEQAVTVSVLNLNDNSPILTSGA-GGSVAENAPISTVIYQA 396 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 A+DAD + Y L P + +D A+G + D ES + DG Sbjct: 397 AASDADG--DASFTYSLKP-GGDADLLHVDSATGAVTLRSLADFESKPGYSFTVAVSDGI 453 Query: 664 TPPQSSTVIVHIKIEDINDSPPVFESD---CLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 + + + + D+N++P + + +SEN TT + A D D G + Sbjct: 454 HTTEQE---IAVSVTDVNEAPVITSNGGEATAAISVSENQAAVTT---VTATDVDAGDSR 507 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP-----RKKYELVIRAASPPLW 775 +SI GG D+ F+++ G+ L + D E P Y++ + Sbjct: 508 T--FSITGGADAALFAIDAETGA----LTFLAAPDREKPADVDHNNIYDVQVAVTDRGGL 561 Query: 776 NDVR-VEILVTDVNDNAPV 793 +DV+ + + VTDV ++ V Sbjct: 562 SDVQDLAVSVTDVREHVVV 580 Score = 140 bits (340), Expect = 4e-31 Identities = 128/431 (29%), Positives = 192/431 (44%), Gaps = 41/431 (9%) Query: 155 YTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSL--V 212 Y V++ E+ S PV K+ ATDAD I Y II GN F+ID+ SG +++ Sbjct: 180 YAVTLAEN-SAKGTPV-GKVSATDAD---GDTITYTIIAGNDNGAFAIDAASGAITVADA 234 Query: 213 KTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPI 272 LD+E R + L ++A DG S+T + IN+ D NDNAP TS +V+EN P Sbjct: 235 SKLDFEATREFTLTVQASDG---RLSDTGTVTINLVDRNDNAP-VITSGSSGTVAENAPT 290 Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332 I + A DAD +TY++ + T +TIDP SG V + D ET+ Y Sbjct: 291 DTVIYQAAARDAD--TETTITYSLKPGEDTS----LLTIDPGSGTVTLNNSADFETKTSY 344 Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392 V A DG + A G +AE+ P T + A+D Sbjct: 345 TFTVIAGDGVNSSEQAVTVSVLNLNDNSPILTSGAGG----SVAENAPISTVIYQAAASD 400 Query: 393 ADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT 452 AD D Y + G + S G +T+ DF+ + Y TV+ +D G + Sbjct: 401 ADGDASFTYSLKPGGDADLLHVDS--ATGAVTLRSLADFESKPGYSFTVAVSD-GIHTTE 457 Query: 453 AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512 + +++TD N + N + + V V+ATD D G + T+S++ Sbjct: 458 QEIAVSVTDVNEAPVITSNGGEATAAISVSENQAAVTTVTATDVDAGDSR--TFSITGG- 514 Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSG------YLLTVTARDGGVPSLSDTTD 566 ++ A+ F I+ +TGA+T DRE + Y + V D G LSD D Sbjct: 515 ADAAL------FAIDAETGALTFLAAPDREKPADVDHNNIYDVQVAVTDRG--GLSDVQD 566 Query: 567 VEISVVDVNDN 577 + +SV DV ++ Sbjct: 567 LAVSVTDVREH 577 Score = 133 bits (321), Expect = 8e-29 Identities = 114/385 (29%), Positives = 177/385 (45%), Gaps = 30/385 (7%) Query: 90 FRIDGRSGALLTR--ASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 F ID SGA+ + LD E +T+ V+A+D RLS T T+ +N++D NDN Sbjct: 220 FAIDAASGAITVADASKLDFEATREFTLTVQASD------GRLSDTGTVTINLVDRNDNA 273 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 P + + + +V E+ + TD VI + A DAD + I Y++ G +ID SG Sbjct: 274 PVITSGS-SGTVAEN-APTDT-VIYQAAARDADT--ETTITYSLKPGEDTSLLTIDPGSG 328 Query: 208 DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 V+L + D+E SY + A DG + S T +++ ++NDN+P TS SV+ Sbjct: 329 TVTLNNSADFETKTSYTFTVIAGDGVNSSEQAVT---VSVLNLNDNSP-ILTSGAGGSVA 384 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 EN PI I + A DAD +A TY++ G+ DL + +D +G V D E Sbjct: 385 ENAPISTVIYQAAASDADG--DASFTYSLKP---GGDADL-LHVDSATGAVTLRSLADFE 438 Query: 328 TQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387 ++ Y V +DG A + ++E++ V T Sbjct: 439 SKPGYSFTVAVSDGIHTTEQEIAVSVTDVNEAPVITSNGGEATAAISVSENQ---AAVTT 495 Query: 388 LTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA----QPLDFKQERRYVLTVSA 443 +TATD D + + ITGG F+I ++ G A +P D Y + V+ Sbjct: 496 VTATDVDAGDSRTFSITGGADAALFAIDAETGALTFLAAPDREKPADVDHNNIYDVQVAV 555 Query: 444 TDSGGRSDTAMVQINITDANNYAPV 468 TD GG SD + +++TD + V Sbjct: 556 TDRGGLSDVQDLAVSVTDVREHVVV 580 Score = 125 bits (301), Expect = 2e-26 Identities = 126/443 (28%), Positives = 204/443 (46%), Gaps = 43/443 (9%) Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523 N+ P N Y ++ E++ GT V VSATD+D ITY++ + N A Sbjct: 172 NFMPNLGN--YAVTLAENSAKGTPVGKVSATDAD---GDTITYTIIAGNDNGA------- 219 Query: 524 FVINPQTGAITTNKL--LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF 581 F I+ +GAIT LD E + LTV A DG LSDT V I++VD NDN PV Sbjct: 220 FAIDAASGAITVADASKLDFEATREFTLTVQASDG---RLSDTGTVTINLVDRNDNAPVI 276 Query: 582 KQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT 641 + + E+A T + Q A DAD I Y L P + + IDP SG + Sbjct: 277 TSGS-SGTVAENAPTDTVIYQAAARDADTETT--ITYSLKPGE-DTSLLTIDPGSGTVTL 332 Query: 642 NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSP 701 N + D E+ ++ +A DG SS V + + ++ND+ P+ S ++EN+P Sbjct: 333 NNSADFETKTSYTFTVIAGDG---VNSSEQAVTVSVLNLNDNSPILTSGA-GGSVAENAP 388 Query: 702 IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDL-DYESPR 760 I T I + A D D +A YS+K G D++ +++ G+ VT+ L D+ES + Sbjct: 389 ISTVIYQAAASDADG--DASFTYSLKPGGDADLLHVDSATGA-----VTLRSLADFES-K 440 Query: 761 KKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYD 820 Y + + + + + VTDVN+ + + V A D Sbjct: 441 PGYSFTVAVSDGIHTTEQEIAVSVTDVNEAPVITSNGGEATAAISVSENQAAVTTVTATD 500 Query: 821 ADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVP------KLATMEVSVTD--G 872 D D + I G +A L ++ TG++T + P + ++V+VTD G Sbjct: 501 VDAGDSRTFSITGGADAALFAIDAETGALTFLAAPDREKPADVDHNNIYDVQVAVTDRGG 560 Query: 873 VNEIKAMMQLSVRLITEEMLLNS 895 +++++ + +SV + E +++ + Sbjct: 561 LSDVQD-LAVSVTDVREHVVVEA 582 >UniRef50_Q12864 Cluster: Cadherin-17 precursor; n=25; Tetrapoda|Rep: Cadherin-17 precursor - Homo sapiens (Human) Length = 832 Score = 161 bits (392), Expect = 2e-37 Identities = 204/724 (28%), Positives = 318/724 (43%), Gaps = 74/724 (10%) Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 ++F I+ R G L +LDRE + + + V A D + + I + + D NDN Sbjct: 68 NIFVIE-REGLLYYNRALDRETRSTHNLQVAALDANGII---VEGPVPITIKVKDINDNR 123 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA--NSAIRYAIIGG----NTQMQFS 201 P F + Y SV ++ S P + + ATD D A N + Y I+ N M F Sbjct: 124 PTFLQSKYEGSVRQN-SRPGKPFL-YVNATDLDDPATPNGQLYYQIVIQLPMINNVMYFQ 181 Query: 202 IDSLSGDVSLVK----TLDYEQVRSYRLVIRAQDGGSPSR---SNTTQLLINIRDVNDNA 254 I++ +G +SL + L+ + SY LVI +D G S S+TT + I + + A Sbjct: 182 INNKTGAISLTREGSQELNPAKNPSYNLVISVKDMGGQSENSFSDTTSVDIIVTENIWKA 241 Query: 255 PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR 314 P+ + E+ ++ PI + VR D G Y++ DK+ P +ID + Sbjct: 242 PKPVEMV--ENSTDPHPIKITQVRWN----DPGAQ----YSLVDKEKLPR--FPFSID-Q 288 Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374 G +Y + LDRE + Y A D P S E Sbjct: 289 EGDIYVTQPLDREEKDAYVFYAVAKDEYGKPLSYPLEIHVKVKDINDNPPTCPSPVTVFE 348 Query: 375 LAEDEPPGTPVVTLTATDADEDNR----LHYEITGGNTR----GRFSITSQNGRGLITVA 426 + E+E G + TLTA D DE+N L+Y I + G F I Q G++ +A Sbjct: 349 VQENERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDGLFLI--QTYAGMLQLA 406 Query: 427 -QPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPY-TASVFEDAPI 484 Q L + +Y LT+ +D ++ VQIN+ D N+ P+FE + Y ++ ED I Sbjct: 407 KQSLKKQDTPQYNLTIEVSDKDFKT-LCFVQINVIDINDQIPIFEKSDYGNLTLAEDTNI 465 Query: 485 GTTVLVVSATDSDVGI--NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE 542 G+T+L + ATD+D +++I Y + I ++ + TG + K LD E Sbjct: 466 GSTILTIQATDADEPFTGSSKILYHI---IKGDSEGRLGVDTDPHTNTGYVIIKKPLDFE 522 Query: 543 TMSGYLLTVTARD------GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALV 596 T + + A + G + S + V DVN+ P F Q ++ A + ED + Sbjct: 523 TAAVSNIVFKAENPEPLVFGVKYNASSFAKFTLIVTDVNE-APQFSQHVFQAKVSEDVAI 581 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 GT V V A D + GL+ I Y L R G ID +G I + LDRE+ + + ++ Sbjct: 582 GTKVGNVTAKDPE-GLD--ISYSLRGDTR--GWLKIDHVTGEIFSVAPLDREAGSPYRVQ 636 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCL-TFYISENSPIGTTIGEIRAHDPD 715 VA + G SS H+ + D+ND+PP D F+ S G+ I E D Sbjct: 637 VVATEVGGSSLSSVSEFHLILMDVNDNPPRLAKDYTGLFFCHPLSAPGSLIFEATDDDQH 696 Query: 716 --EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR---AA 770 GP+ +S+ G N + + G+ A L T D+E ++Y ++IR Sbjct: 697 LFRGPHFT--FSLGSGSLQNDWEVSKINGT-HARLSTR-HTDFE--EREYVVLIRINDGG 750 Query: 771 SPPL 774 PPL Sbjct: 751 RPPL 754 Score = 134 bits (325), Expect = 3e-29 Identities = 178/693 (25%), Positives = 289/693 (41%), Gaps = 80/693 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD--IGKNAEVEYTIELVTAD 68 I V D ND+ P F +YE SVR+ + G L + ATD D N ++ Y I ++ Sbjct: 114 IKVKDINDNRPTFLQSKYEGSVRQNSRPGKPFLYVNATDLDDPATPNGQLYYQI-VIQLP 172 Query: 69 TLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTR---ASLDREKVARYTVLVKATDQAS 124 +N V F+I+ ++GA+ LTR L+ K Y +++ D Sbjct: 173 MIN-------------NVM-YFQINNKTGAISLTREGSQELNPAKNPSYNLVISVKDMGG 218 Query: 125 PVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV-IAKIKATDADVGA 183 + S T ++ + + ++ P+ V + E+ S +P+ I +++ D GA Sbjct: 219 QSENSFSDTTSVDIIVTENIWKAPK------PVEMVEN-STDPHPIKITQVRWNDP--GA 269 Query: 184 NSAIRYAIIGGN--TQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 +Y+++ + FSID GD+ + + LD E+ +Y A+D S Sbjct: 270 ----QYSLVDKEKLPRFPFSIDQ-EGDIYVTQPLDREEKDAYVFYAVAKDEYGKPLSYPL 324 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE--GVNAELTYTMTDK 299 ++ + ++D+NDN P + + V EN +G SI + A+D DE N+ L Y + ++ Sbjct: 325 EIHVKVKDINDNPPTCPSPVTVFEVQENERLGNSIGTLTAHDRDEENTANSFLNYRIVEQ 384 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATDGGDPPRSATATXXXXXXX 358 +D I +G + + Q L ++ +Y L + + D Sbjct: 385 TPKLPMDGLFLIQTYAGMLQLAKQSLKKQDTPQYNLTIEVS---DKDFKTLCFVQINVID 441 Query: 359 XXXXXXXFMPGQY-EVELAEDEPPGTPVVTLTATDADE----DNRLHYEITGGNTRGRFS 413 F Y + LAED G+ ++T+ ATDADE +++ Y I G++ GR Sbjct: 442 INDQIPIFEKSDYGNLTLAEDTNIGSTILTIQATDADEPFTGSSKILYHIIKGDSEGRLG 501 Query: 414 ITS--QNGRGLITVAQPLDFKQERRYVLTVSATD--------SGGRSDTAMVQINITDAN 463 + + G + + +PLDF+ + A + S A + +TD N Sbjct: 502 VDTDPHTNTGYVIIKKPLDFETAAVSNIVFKAENPEPLVFGVKYNASSFAKFTLIVTDVN 561 Query: 464 NYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ 523 AP F + A V ED IGT V V+A D + G++ I+YSL + H Sbjct: 562 E-APQFSQHVFQAKVSEDVAIGTKVGNVTAKDPE-GLD--ISYSLRGDTRGWLKIDH--- 614 Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583 TG I + LDRE S Y + V A + G SLS ++ + ++DVNDN P + Sbjct: 615 -----VTGEIFSVAPLDREAGSPYRVQVVATEVGGSSLSSVSEFHLILMDVNDNPPRLAK 669 Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVID-PASGVIRTN 642 YT L ATD D L H+ GS D S + T+ Sbjct: 670 D-YTGLFFCHPLSAPGSLIFEATDDDQHLFRGPHFTF---SLGSGSLQNDWEVSKINGTH 725 Query: 643 KALDRESVATHDLKAVAI----DGGTPPQSSTV 671 L + + V + DGG PP V Sbjct: 726 ARLSTRHTDFEEREYVVLIRINDGGRPPLEGIV 758 Score = 131 bits (317), Expect = 2e-28 Identities = 158/636 (24%), Positives = 269/636 (42%), Gaps = 52/636 (8%) Query: 194 GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDN 253 G T F I+ G + + LD E ++ L + A D + I ++D+NDN Sbjct: 64 GETDNIFVIER-EGLLYYNRALDRETRSTHNLQVAALDANGIIVEGPVPITIKVKDINDN 122 Query: 254 APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV--NAELTYTMTDKDYTGNVDLPITI 311 P F S ++ SV +N G + V A D D+ N +L Y + + N + I Sbjct: 123 RPTFLQSKYEGSVRQNSRPGKPFLYVNATDLDDPATPNGQLYYQIVIQLPMINNVMYFQI 182 Query: 312 DPRSGWVYT----SGQLDRETQAKYQLLVTATD-GGDPPRSATATXXXXXXXXXXXXXXF 366 + ++G + S +L+ Y L+++ D GG S + T Sbjct: 183 NNKTGAISLTREGSQELNPAKNPSYNLVISVKDMGGQSENSFSDTTSVDIIVTENIWKAP 242 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVA 426 P VE+ E+ P + +T + D Y + RF S + G I V Sbjct: 243 KP----VEMVENSTDPHP-IKITQVRWN-DPGAQYSLVDKEKLPRFPF-SIDQEGDIYVT 295 Query: 427 QPLDFKQERRYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 QPLD +++ YV A D G+ S + + + D N+ P + V E+ + Sbjct: 296 QPLDREEKDAYVFYAVAKDEYGKPLSYPLEIHVKVKDINDNPPTCPSPVTVFEVQENERL 355 Query: 485 GTTVLVVSATDSDV--GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNK-LLDR 541 G ++ ++A D D N+ + Y + + + D F+I G + K L + Sbjct: 356 GNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPM---DGLFLIQTYAGMLQLAKQSLKK 412 Query: 542 ETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY-TANIMEDALVGTSV 600 + Y LT+ D +L V+I+V+D+ND P+F++ Y + ED +G+++ Sbjct: 413 QDTPQYNLTIEVSDKDFKTL---CFVQINVIDINDQIPIFEKSDYGNLTLAEDTNIGSTI 469 Query: 601 SQVGATDADVGLNG--RIHYELDPKDREEGSFVID----PASGVIRTNKALDRESVATHD 654 + ATDAD G +I Y + D EG +D +G + K LD E+ A + Sbjct: 470 LTIQATDADEPFTGSSKILYHIIKGD-SEGRLGVDTDPHTNTGYVIIKKPLDFETAAVSN 528 Query: 655 LKAVA------IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE 708 + A + G SS + + D+N++P F +SE+ IGT +G Sbjct: 529 IVFKAENPEPLVFGVKYNASSFAKFTLIVTDVNEAPQ-FSQHVFQAKVSEDVAIGTKVGN 587 Query: 709 IRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYE--SPRKKYELV 766 + A DP EG + + YS++ GD ++ G E+ ++ LD E SP + + Sbjct: 588 VTAKDP-EGLD--ISYSLR-GDTRGWLKIDHVTG----EIFSVAPLDREAGSPYRVQVVA 639 Query: 767 IRAASPPLWNDVRVEILVTDVNDNAP-VMKDFQIIF 801 L + +++ DVNDN P + KD+ +F Sbjct: 640 TEVGGSSLSSVSEFHLILMDVNDNPPRLAKDYTGLF 675 Score = 104 bits (250), Expect = 3e-20 Identities = 114/412 (27%), Positives = 182/412 (44%), Gaps = 38/412 (9%) Query: 401 YEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR--SDTAMVQIN 458 +E+TG T F I + GL+ + LD + + L V+A D+ G + I Sbjct: 60 FELTG-ETDNIFVIERE---GLLYYNRALDRETRSTHNLQVAALDANGIIVEGPVPITIK 115 Query: 459 ITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD--VGINAQITYSLSSEISNEA 516 + D N+ P F + Y SV +++ G L V+ATD D N Q+ Y + ++ Sbjct: 116 VKDINDNRPTFLQSKYEGSVRQNSRPGKPFLYVNATDLDDPATPNGQLYYQIVIQLP--- 172 Query: 517 VAHHDQQFVINPQTGAITTNKLLDRETMSG----YLLTVTARD-GGVP--SLSDTTDVEI 569 + ++ F IN +TGAI+ + +E Y L ++ +D GG S SDTT V+I Sbjct: 173 MINNVMYFQINNKTGAISLTREGSQELNPAKNPSYNLVISVKDMGGQSENSFSDTTSVDI 232 Query: 570 SVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS 629 V E ++K ++E++ T + T G + +D + Sbjct: 233 IVT-----ENIWKAPK-PVEMVENS---TDPHPIKITQVRWNDPGAQYSLVDKEKLPRFP 283 Query: 630 FVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFES 689 F ID G I + LDRE + AVA D P S + +H+K++DIND+PP S Sbjct: 284 FSIDQ-EGDIYVTQPLDREEKDAYVFYAVAKDEYGKPLSYPLEIHVKVKDINDNPPTCPS 342 Query: 690 DCLTFYISENSPIGTTIGEIRAHDPDE--GPNAVVHYSIKGGDD----SNSFSLETRQGS 743 F + EN +G +IG + AHD DE N+ ++Y I F ++T G Sbjct: 343 PVTVFEVQENERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDGLFLIQTYAG- 401 Query: 744 DKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMK 795 +L ++P +Y L I + V+I V D+ND P+ + Sbjct: 402 -MLQLAKQSLKKQDTP--QYNLTIEVSDKDFKTLCFVQINVIDINDQIPIFE 450 Score = 101 bits (243), Expect = 2e-19 Identities = 116/477 (24%), Positives = 205/477 (42%), Gaps = 50/477 (10%) Query: 1 MSVPFCIHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEY 60 +S P IH + V D ND+ P V+E G ++ TL A D+D A Sbjct: 320 LSYPLEIH--VKVKDINDNPPTCPSPVTVFEVQENERLGNSIGTLTAHDRDEENTANSFL 377 Query: 61 TIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLVKA 119 +V P D +F I +G L L + SL ++ +Y + ++ Sbjct: 378 NYRIVEQTPKLPMDG-------------LFLIQTYAGMLQLAKQSLKKQDTPQYNLTIEV 424 Query: 120 TDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY-TVSVDEDISVTDNPVIAKIKATD 178 +D+ + + +N+ID ND P F + Y +++ ED ++ I I+ATD Sbjct: 425 SDK------DFKTLCFVQINVIDINDQIPIFEKSDYGNLTLAEDTNI--GSTILTIQATD 476 Query: 179 AD--VGANSAIRYAIIGGNTQMQFSID----SLSGDVSLVKTLDYEQVRSYRLVIRAQD- 231 AD +S I Y II G+++ + +D + +G V + K LD+E +V +A++ Sbjct: 477 ADEPFTGSSKILYHIIKGDSEGRLGVDTDPHTNTGYVIIKKPLDFETAAVSNIVFKAENP 536 Query: 232 -----GGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE 286 G + S+ + + + DVN+ AP+F +FQ VSE+V IG + V A D E Sbjct: 537 EPLVFGVKYNASSFAKFTLIVTDVNE-APQFSQHVFQAKVSEDVAIGTKVGNVTAKD-PE 594 Query: 287 GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR 346 G+ +++Y++ G+ + ID +G +++ LDRE + Y++ V AT+ G Sbjct: 595 GL--DISYSL-----RGDTRGWLKIDHVTGEIFSVAPLDREAGSPYRVQVVATEVGGSSL 647 Query: 347 SATATXXXXXXXXXXXXXXFMPGQYEVELAED-EPPGTPVVTLTATDADEDNRLH--YEI 403 S+ + + PG+ + T D H + + Sbjct: 648 SSVSEFHLILMDVNDNPPRLAKDYTGLFFCHPLSAPGSLIFEATDDDQHLFRGPHFTFSL 707 Query: 404 TGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINIT 460 G+ + + ++ NG + DF +ER YV+ + D G +V + +T Sbjct: 708 GSGSLQNDWEVSKINGTHARLSTRHTDF-EEREYVVLIRINDGGRPPLEGIVSLPVT 763 >UniRef50_P55283 Cluster: Cadherin-4 precursor; n=74; cellular organisms|Rep: Cadherin-4 precursor - Homo sapiens (Human) Length = 916 Score = 160 bits (389), Expect = 4e-37 Identities = 160/549 (29%), Positives = 244/549 (44%), Gaps = 50/549 (9%) Query: 187 IRYAIIG-GNTQ--MQ-FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQ 242 IRY+I G G Q M+ FSIDS+SG + + + +D E+ SY L A D N Sbjct: 203 IRYSITGVGADQPPMEVFSIDSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNKVENPID 262 Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG--VNAELTYTMTDKD 300 L I + D+NDN P F ++ SV E G ++ V A DAD+ N + Y + + Sbjct: 263 LYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQT 322 Query: 301 YTGNVDLPITIDPRSGWVYT-SGQLDRETQAKYQLLVTATD--GG-DPPRSATATXXXXX 356 TI+ +G + T + LDRE +Y ++V ATD G + S TAT Sbjct: 323 PQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITV 382 Query: 357 XXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH----YEITGGNTRGRF 412 F + E+ E+ T V LT D D+ + + Y I G+ G F Sbjct: 383 TDVNDNPPEFTASTFAGEVPENRVE-TVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHF 441 Query: 413 SITSQ--NGRGLITVAQPLDFKQERRYVLTVSATD-----SG---GRSDTAMVQINITDA 462 S+ + G++TV + +D++ R ++LTV ++ SG TA V I+I D Sbjct: 442 SVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPLASGIQMSFQSTAGVTISIMDI 501 Query: 463 NNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQ 522 N AP F + + E P GT + SA D D + + Y S++S+ A H Sbjct: 502 NE-APYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAVRY---SKLSDPASWLH-- 555 Query: 523 QFVINPQTGAITTNKLLDRETM----SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578 IN G ITT +LDRE++ + Y T A D G+P S T ++I ++D+NDN Sbjct: 556 ---INATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGTLQIYLIDINDNA 612 Query: 579 PVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN-GRIHYELD--PKDREEGSFVIDPA 635 P + A I E + + A DADV N G +EL P + + Sbjct: 613 PELLPK--EAQICEKP--NLNAINITAADADVDPNIGPYVFELPFVPAAVRKNWTITRLN 668 Query: 636 SGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695 + + + +D+ + D G PP S+T I+ +K+ +D+ DC T Sbjct: 669 GDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCDDN-----GDCTTIG 723 Query: 696 ISENSPIGT 704 + +GT Sbjct: 724 AVAAAGLGT 732 Score = 149 bits (360), Expect = 1e-33 Identities = 135/473 (28%), Positives = 218/473 (46%), Gaps = 51/473 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I V+D ND+ P F Q Y SV EG+ GT V+T+ A D D A +VT Sbjct: 265 IYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQ 324 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLT-RASLDREKVARYTVLVKATDQASPVSDR 129 +P Q++F I+ +G ++T A LDREKV +YTV+V+ATD ++ Sbjct: 325 SPS-------------QNMFTINSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLNYG 371 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV--GANSAI 187 LS+TAT + + D NDN P+F+ T+ V E+ T V+A + D D N Sbjct: 372 LSNTATAIITVTDVNDNPPEFTASTFAGEVPENRVET---VVANLTVMDRDQPHSPNWNA 428 Query: 188 RYAIIGGNTQMQFSI--DSLS--GDVSLVKTLDYEQVRSYRLVIRAQD------GGSPSR 237 Y II G+ FS+ D ++ G V++VK +DYE R++ L + + G S Sbjct: 429 VYRIISGDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPLASGIQMSF 488 Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297 +T + I+I D+N+ AP F ++ + E VP G + A D D + + Y+ Sbjct: 489 QSTAGVTISIMDINE-APYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAVRYSKL 547 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRET----QAKYQLLVTATDGGDPPRSATATXX 353 + + I+ +G + T+ LDRE+ Y+ A D G PP S T T Sbjct: 548 SDPASW-----LHINATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGTLQ 602 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH---YEI--TGGNT 408 +P + ++ E P + +TA DAD D + +E+ Sbjct: 603 IYLIDINDNAPELLPKEAQI----CEKPNLNAINITAADADVDPNIGPYVFELPFVPAAV 658 Query: 409 RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG--RSDTAMVQINI 459 R ++IT NG ++ + + + Y + + TDSG S+T+++++ + Sbjct: 659 RKNWTITRLNG-DYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKV 710 Score = 136 bits (328), Expect = 1e-29 Identities = 138/514 (26%), Positives = 217/514 (42%), Gaps = 39/514 (7%) Query: 88 DVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNY 147 +VF ID SG + +DRE+ A Y + A D +++ + +++ +ID NDN Sbjct: 218 EVFSIDSMSGRMYVTRPMDREEHASYHLRAHAVDMNG---NKVENPIDLYIYVIDMNDNR 274 Query: 148 PQFSEKTYTVSVDEDISVTDNPVIAKIKATDAD--VGANSAIRYAII----GGNTQMQFS 201 P+F + Y SVDE + + A DAD AN +RY I+ +Q F+ Sbjct: 275 PEFINQVYNGSVDE--GSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFT 332 Query: 202 IDSLSGD-VSLVKTLDYEQVRSYRLVIRAQD--GG-SPSRSNTTQLLINIRDVNDNAPRF 257 I+S +GD V++ LD E+V+ Y ++++A D G + SNT +I + DVNDN P F Sbjct: 333 INSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEF 392 Query: 258 YTSLFQESVSEN-VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG 316 S F V EN V + + V D N Y + D +G+ + G Sbjct: 393 TASTFAGEVPENRVETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEG 452 Query: 317 WVYTSGQLDRETQAKYQLLVTATD----GGDPPRSATATXXXXXXXXXXXXXXFMPGQYE 372 V +D E + L V ++ S +T + P ++ Sbjct: 453 MVTVVKAVDYELNRAFMLTVMVSNQAPLASGIQMSFQSTAGVTISIMDINEAPYFPSNHK 512 Query: 373 -VELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPL 429 + L E PPGT + T +A D D + Y + I + NG+ IT A L Sbjct: 513 LIRLEEGVPPGTVLTTFSAVDPDRFMQQAVRYSKL-SDPASWLHINATNGQ--ITTAAVL 569 Query: 430 D----FKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 D + + Y T A D+G S T +QI + D N+ AP E P A + E Sbjct: 570 DRESLYTKNNVYEATFLAADNGIPPASGTGTLQIYLIDINDNAP--ELLPKEAQICEKPN 627 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 + + ++A D+DV N Y AV + +N ++ L Sbjct: 628 L--NAINITAADADVDPNIG-PYVFELPFVPAAVRKNWTITRLNGDYAQLSLRILYLEAG 684 Query: 544 MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDN 577 M Y + + D G P LS+T+ +++ V +DN Sbjct: 685 M--YDVPIIVTDSGNPPLSNTSIIKVKVCPCDDN 716 Score = 126 bits (305), Expect = 7e-27 Identities = 137/442 (30%), Positives = 192/442 (43%), Gaps = 47/442 (10%) Query: 391 TDADEDNRLHYEITGGNTRGR----FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446 +D D D + Y ITG FSI S +GR +T +P+D ++ Y L A D Sbjct: 195 SDKDNDIPIRYSITGVGADQPPMEVFSIDSMSGRMYVT--RPMDREEHASYHLRAHAVDM 252 Query: 447 GGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD--VGINA 502 G + + I + D N+ P F N Y SV E + GT V+ V+A D+D N Sbjct: 253 NGNKVENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADDSTTANG 312 Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL-LDRETMSGYLLTVTARD--GGVP 559 + Y + ++ + F IN +TG I T LDRE + Y + V A D G + Sbjct: 313 MVRYRI---VTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLN 369 Query: 560 -SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV--GLNGRI 616 LS+T I+V DVNDN P F + + E+ V T V+ + D D N Sbjct: 370 YGLSNTATAIITVTDVNDNPPEFTASTFAGEVPENR-VETVVANLTVMDRDQPHSPNWNA 428 Query: 617 HYELDPKDREEGSFVI--DPAS--GVIRTNKALDRESVATHDLKAVAIDGGTPPQS---- 668 Y + D G F + DP + G++ KA+D E L V + P S Sbjct: 429 VYRIISGD-PSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFML-TVMVSNQAPLASGIQM 486 Query: 669 ---STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 ST V I I DIN++P F S+ + E P GT + A DPD V YS Sbjct: 487 SFQSTAGVTISIMDINEAP-YFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAVRYS 545 Query: 726 IKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK---YELVIRAAS---PPLWNDVR 779 K D ++ + G ++ T LD ES K YE AA PP Sbjct: 546 -KLSDPASWLHINATNG----QITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGT 600 Query: 780 VEILVTDVNDNAPVM--KDFQI 799 ++I + D+NDNAP + K+ QI Sbjct: 601 LQIYLIDINDNAPELLPKEAQI 622 Score = 106 bits (255), Expect = 8e-21 Identities = 97/354 (27%), Positives = 160/354 (45%), Gaps = 24/354 (6%) Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583 F I+ +G + + +DRE + Y L A D + + D+ I V+D+NDN P F Sbjct: 220 FSIDSMSGRMYVTRPMDREEHASYHLRAHAVDMNGNKVENPIDLYIYVIDMNDNRPEFIN 279 Query: 584 QLYTANIMEDALVGTSVSQVGATDAD--VGLNGRIHYEL---DPKDREEGSFVIDPASGV 638 Q+Y ++ E + GT V V A DAD NG + Y + P+ + F I+ +G Sbjct: 280 QVYNGSVDEGSKPGTYVMTVTANDADDSTTANGMVRYRIVTQTPQSPSQNMFTINSETGD 339 Query: 639 IRTNKA-LDRESVATHDL--KAVAIDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTF 694 I T A LDRE V + + +A ++G S+T I + D+ND+PP F + Sbjct: 340 IVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSNTATAIITVTDVNDNPPEFTASTFAG 399 Query: 695 YISENSPIGTTIGEIRAHDPDE--GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMV 752 + EN + T + + D D+ PN Y I GD S FS+ T +++ + + Sbjct: 400 EVPENR-VETVVANLTVMDRDQPHSPNWNAVYRIISGDPSGHFSVRTDPVTNEGMVTVVK 458 Query: 753 DLDYESPRKKYELVIRAASPPLWNDVR--------VEILVTDVNDNAPVMKDFQIIFNNY 804 +DYE R V+ + PL + ++ V I + D+N+ AP + Sbjct: 459 AVDYELNRAFMLTVMVSNQAPLASGIQMSFQSTAGVTISIMDINE-APYFPSNHKLIRLE 517 Query: 805 KDCFPVGPFGRVPAYDAD--VTDKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 + P A D D + ++Y LS + A+ + +N T G +T + L+ Sbjct: 518 EGVPPGTVLTTFSAVDPDRFMQQAVRYSKLS-DPASWLHINATNGQITTAAVLD 570 >UniRef50_Q9VEU1 Cluster: Cadherin 89D precursor; n=3; Sophophora|Rep: Cadherin 89D precursor - Drosophila melanogaster (Fruit fly) Length = 2240 Score = 157 bits (381), Expect = 4e-36 Identities = 160/561 (28%), Positives = 249/561 (44%), Gaps = 55/561 (9%) Query: 243 LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVR-VQAYDADEG--VNAELTYTMTDK 299 + + I DVNDNAP F + V EN I I VQA+D D+ N+E+ ++M+ Sbjct: 165 ITVYIEDVNDNAPEFLNVPYVVDVDENTSIESIIFEGVQAFDRDKPNTPNSEVHFSMSTV 224 Query: 300 DYTGNVD-LPITI--DPRSGWVYTSGQLDRETQAK-YQLLVTATDGGDPPRSATATXXXX 355 + D P P + +LD + + ++L + A D G P A T Sbjct: 225 PEQLSADGSPYFALKSPHRPLLILKRELDFDNGIRQFKLPIFAWDRGTPANQANTTITIN 284 Query: 356 XXXXXXXXXXFMPGQYEVELAEDEP-PGTPV-------VTLTATDADEDNR-LHYEITGG 406 F G Y + E P G P+ + A D D N L Y+I G Sbjct: 285 VRDVDDLPPKFTEGVYRTRINEFYPMTGVPIRIPLYFAPPIMAFDQDSLNASLVYDIISG 344 Query: 407 NTRGRFSITSQNGRGLITVAQPLDFKQE----RRYVLTVSAT--DSGGRSDTAMVQINIT 460 N R F + NG ++ + + +D ++E +VL + A D+ + A +++ + Sbjct: 345 NERQLFRVNPHNG--VMYLQKEIDLEEESLPGNTFVLQLEARQKDNPLKKALARIEVEVL 402 Query: 461 DANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHH 520 D N+ P FE Y S+ E+ P G +VL V+A D D G N++ Y+L E + A A Sbjct: 403 DLNDNVPEFEADYYNISIVENLPTGFSVLQVNAVDRDQGENSEFLYNLV-ETKDAAGA-- 459 Query: 521 DQQFVINPQTGAITT--NKLLDRETMSGYLLTVTARDGGVPSLSDT---------TDVEI 569 F I+ +TG IT ++LLDRE L V A + L D VEI Sbjct: 460 ---FRIDSRTGWITVRDDRLLDREQRRSIQLNVEALERNPSYLDDKHLKKPGPSKVQVEI 516 Query: 570 SVVDVNDNEPVFKQ-QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELD-PKDREE 627 +++D NDN P F+ LY + +A G + QV A D D G NG + YEL PK Sbjct: 517 TLLDTNDNTPKFEHGNLYEFKVPINAPTGYVIGQVVAHDPDEGPNGHLLYELQRPKGSGY 576 Query: 628 GSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQS---STVIVHIKI-EDINDS 683 F +D +G I L R +A A D T P S ++ I++ I+D Sbjct: 577 IPFRLDNKNGTIYVGGPLRRGRIAVF---VEATDQPTNPSERRFSLAVITIEVYATIDDQ 633 Query: 684 PPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 F F++ N+P+GT++G++R EG + +++ + + F++E R G Sbjct: 634 AIDFVGAPYEFWVGANTPLGTSVGQVRTTLIYEGGDEIMYDLLHTYSEGVPFAIEERSG- 692 Query: 744 DKAELVTMVDLDYESPRKKYE 764 ++T++ E RK Y+ Sbjct: 693 ----IITVIRELSEFKRKVYQ 709 Score = 128 bits (310), Expect = 2e-27 Identities = 133/519 (25%), Positives = 221/519 (42%), Gaps = 58/519 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-LKATDQDIGK--NAEVEYTIELVTA 67 + + D ND++P F Y V E S + + ++A D+D N+EV +++ V Sbjct: 167 VYIEDVNDNAPEFLNVPYVVDVDENTSIESIIFEGVQAFDRDKPNTPNSEVHFSMSTV-- 224 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREK-VARYTVLVKATDQASPV 126 PE L+ + LD + + ++ + + A D+ +P Sbjct: 225 ----PEQLSADGSPYFALKSP------HRPLLILKRELDFDNGIRQFKLPIFAWDRGTPA 274 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPV------IAKIKATDAD 180 + + TI +N+ D +D P+F+E Y ++E +T P+ I A D D Sbjct: 275 NQ---ANTTITINVRDVDDLPPKFTEGVYRTRINEFYPMTGVPIRIPLYFAPPIMAFDQD 331 Query: 181 VGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV----RSYRLVIRAQDGGSPS 236 N+++ Y II GN + F ++ +G + L K +D E+ ++ L + A+ +P Sbjct: 332 -SLNASLVYDIISGNERQLFRVNPHNGVMYLQKEIDLEEESLPGNTFVLQLEARQKDNPL 390 Query: 237 RSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 + ++ + + D+NDN P F + S+ EN+P G+S+++V A D D+G N+E Y + Sbjct: 391 KKALARIEVEVLDLNDNVPEFEADYYNISIVENLPTGFSVLQVNAVDRDQGENSEFLYNL 450 Query: 297 TD-KDYTGNVDLPITIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGG---------DP 344 + KD G ID R+GW+ LDRE + QL V A + Sbjct: 451 VETKDAAG----AFRIDSRTGWITVRDDRLLDREQRRSIQLNVEALERNPSYLDDKHLKK 506 Query: 345 PRSATATXXXXXXXXXXXXXXFMPGQ-YEVELAEDEPPGTPVVTLTATDADE--DNRLHY 401 P + F G YE ++ + P G + + A D DE + L Y Sbjct: 507 PGPSKVQVEITLLDTNDNTPKFEHGNLYEFKVPINAPTGYVIGQVVAHDPDEGPNGHLLY 566 Query: 402 EITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATD-----SGGRSDTAMVQ 456 E+ G N G I V PL + R + V ATD S R A++ Sbjct: 567 ELQRPKGSGYIPFRLDNKNGTIYVGGPL---RRGRIAVFVEATDQPTNPSERRFSLAVIT 623 Query: 457 INI-TDANNYAPVFENAPYTASVFEDAPIGTTVLVVSAT 494 I + ++ A F APY V + P+GT+V V T Sbjct: 624 IEVYATIDDQAIDFVGAPYEFWVGANTPLGTSVGQVRTT 662 Score = 122 bits (294), Expect = 1e-25 Identities = 138/565 (24%), Positives = 237/565 (41%), Gaps = 48/565 (8%) Query: 132 STATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV--GANSAIRY 189 S +I V I D NDN P+F Y V VDE+ S+ ++ + ++A D D NS + + Sbjct: 161 SYLSITVYIEDVNDNAPEFLNVPYVVDVDENTSI-ESIIFEGVQAFDRDKPNTPNSEVHF 219 Query: 190 AI------IGGNTQMQFSIDSLSGDVSLVK-TLDYEQ-VRSYRLVIRAQDGGSPSRSNTT 241 ++ + + F++ S + ++K LD++ +R ++L I A D G+P+ T Sbjct: 220 SMSTVPEQLSADGSPYFALKSPHRPLLILKRELDFDNGIRQFKLPIFAWDRGTPANQANT 279 Query: 242 QLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDA-------DEGVNAELTY 294 + IN+RDV+D P+F +++ ++E P+ +R+ Y A + +NA L Y Sbjct: 280 TITINVRDVDDLPPKFTEGVYRTRINEFYPMTGVPIRIPLYFAPPIMAFDQDSLNASLVY 339 Query: 295 TMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA----KYQLLVTATDGGDPPRSATA 350 + +GN ++P +G +Y ++D E ++ + L + A +P + A A Sbjct: 340 DI----ISGNERQLFRVNPHNGVMYLQKEIDLEEESLPGNTFVLQLEARQKDNPLKKALA 395 Query: 351 TXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNR---LHYEITGGN 407 F Y + + E+ P G V+ + A D D+ L+ + + Sbjct: 396 RIEVEVLDLNDNVPEFEADYYNISIVENLPTGFSVLQVNAVDRDQGENSEFLYNLVETKD 455 Query: 408 TRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG---------GRSDTAMVQIN 458 G F I S+ G + + LD +Q R L V A + + + VQ+ Sbjct: 456 AAGAFRIDSRTGWITVRDDRLLDREQRRSIQLNVEALERNPSYLDDKHLKKPGPSKVQVE 515 Query: 459 IT--DANNYAPVFENAP-YTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515 IT D N+ P FE+ Y V +AP G + V A D D G N + Y L + Sbjct: 516 ITLLDTNDNTPKFEHGNLYEFKVPINAPTGYVIGQVVAHDPDEGPNGHLLYELQRPKGSG 575 Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVN 575 + F ++ + G I L R ++ ++ + I V Sbjct: 576 YI-----PFRLDNKNGTIYVGGPLRRGRIAVFVEATDQPTNPSERRFSLAVITIEVYATI 630 Query: 576 DNEPV-FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634 D++ + F Y + + +GTSV QV T G I Y+L E F I+ Sbjct: 631 DDQAIDFVGAPYEFWVGANTPLGTSVGQVRTTLIYEG-GDEIMYDLLHTYSEGVPFAIEE 689 Query: 635 ASGVIRTNKALDRESVATHDLKAVA 659 SG+I + L + +AVA Sbjct: 690 RSGIITVIRELSEFKRKVYQFEAVA 714 Score = 107 bits (258), Expect = 3e-21 Identities = 100/373 (26%), Positives = 173/373 (46%), Gaps = 38/373 (10%) Query: 87 QDVFRIDGRSGALLTRASLDREKVA----RYTVLVKATDQASPVSDRLSSTATIHVNIID 142 + +FR++ +G + + +D E+ + + + ++A + +P+ L A I V ++D Sbjct: 347 RQLFRVNPHNGVMYLQKEIDLEEESLPGNTFVLQLEARQKDNPLKKAL---ARIEVEVLD 403 Query: 143 DNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQM-QFS 201 NDN P+F Y +S+ E++ + + ++ A D D G NS Y ++ F Sbjct: 404 LNDNVPEFEADYYNISIVENLPTGFS--VLQVNAVDRDQGENSEFLYNLVETKDAAGAFR 461 Query: 202 IDSLSGDVSLV--KTLDYEQVRSYRLVIRAQDGG----------SPSRSNTTQLLINIRD 249 IDS +G +++ + LD EQ RS +L + A + P S Q+ I + D Sbjct: 462 IDSRTGWITVRDDRLLDREQRRSIQLNVEALERNPSYLDDKHLKKPGPSKV-QVEITLLD 520 Query: 250 VNDNAPRF-YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLP 308 NDN P+F + +L++ V N P GY I +V A+D DEG N L Y + +G + P Sbjct: 521 TNDNTPKFEHGNLYEFKVPINAPTGYVIGQVVAHDPDEGPNGHLLYELQRPKGSGYI--P 578 Query: 309 ITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPR----SATATXXXXXXXXXXXXX 364 +D ++G +Y G L R + + V ATD P S Sbjct: 579 FRLDNKNGTIYVGGPLRR---GRIAVFVEATDQPTNPSERRFSLAVITIEVYATIDDQAI 635 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADE-DNRLHYEITGGNTRG-RFSITSQNGRGL 422 F+ YE + + P GT V + T E + + Y++ + G F+I ++ G+ Sbjct: 636 DFVGAPYEFWVGANTPLGTSVGQVRTTLIYEGGDEIMYDLLHTYSEGVPFAIEERS--GI 693 Query: 423 ITVAQPL-DFKQE 434 ITV + L +FK++ Sbjct: 694 ITVIRELSEFKRK 706 Score = 107 bits (257), Expect = 4e-21 Identities = 74/219 (33%), Positives = 107/219 (48%), Gaps = 15/219 (6%) Query: 477 SVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVA------HHDQQFVINPQT 530 +++ED P+GT VL +SA+D D G NA + Y L E H + F I+ + Sbjct: 1178 AIYEDTPVGTKVLQLSASDEDFGKNALLHYELQGEQVERTPGMPMLRVHGVKYFAIDKLS 1237 Query: 531 GAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANI 590 G ++ N L LTVT DG L D+T + +V+DVN++ P FK+ Y+ + Sbjct: 1238 GELSVNYPLSANIEIMLNLTVTDIDG----LKDSTCLRFTVMDVNNHAPTFKKSWYSFDT 1293 Query: 591 MEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESV 650 E + + Q+ A D D G N I Y L F I PASGV++ LDRE Sbjct: 1294 PEGEYKDSVLGQLTAIDMDFGENANITYTLSDSHL---PFTIKPASGVLKIGGQLDRELK 1350 Query: 651 ATHDLKAVAIDGGTPPQ--SSTVIVHIKIEDINDSPPVF 687 + + +A D Q SS+V V + + DIND+ P F Sbjct: 1351 DKYSFQVIATDNAPVMQRMSSSVDVEVNVLDINDNRPEF 1389 Score = 106 bits (254), Expect = 1e-20 Identities = 104/351 (29%), Positives = 161/351 (45%), Gaps = 56/351 (15%) Query: 377 EDEPPGTPVVTLTATDAD--EDNRLHYEITGGN---TRGR----------FSITSQNGRG 421 ED P GT V+ L+A+D D ++ LHYE+ G T G F+I +G Sbjct: 1181 EDTPVGTKVLQLSASDEDFGKNALLHYELQGEQVERTPGMPMLRVHGVKYFAIDKLSGE- 1239 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 ++V PL E +L ++ TD G D+ ++ + D NN+AP F+ + Y+ E Sbjct: 1240 -LSVNYPLSANIE--IMLNLTVTDIDGLKDSTCLRFTVMDVNNHAPTFKKSWYSFDTPEG 1296 Query: 482 APIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDR 541 + + ++A D D G NA ITY+LS +H F I P +G + LDR Sbjct: 1297 EYKDSVLGQLTAIDMDFGENANITYTLSD-------SH--LPFTIKPASGVLKIGGQLDR 1347 Query: 542 ETMSGYLLTVTARDGG--VPSLSDTTDVEISVVDVNDNEPVF------------------ 581 E Y V A D + +S + DVE++V+D+NDN P F Sbjct: 1348 ELKDKYSFQVIATDNAPVMQRMSSSVDVEVNVLDINDNRPEFIGYDDQTKAVKFIPSVAD 1407 Query: 582 ---KQQLYTANIMEDALVGTSVSQVGATDAD-VGL-NGRIHYELDPKDREEGSFVIDPAS 636 +Y A + GT V Q+ A D D VG NG + Y + ++ + F ID Sbjct: 1408 RTLMLPVYKAYLDRSTQPGTFVRQLTAIDKDNVGNGNGLVLYSIRHQEMQAPLFQIDSRD 1467 Query: 637 GVIRTNKALDRESVATH-DLKAVAIDGGTPPQSST--VIVHIKIEDINDSP 684 G I T ++ + H ++ +A D G+P S+T VIV+++ + + D P Sbjct: 1468 GTISTISRINGYNDYEHLNVSVIASDVGSPALSATAIVIVNLQGQAVTDPP 1518 Score = 105 bits (252), Expect = 2e-20 Identities = 104/396 (26%), Positives = 180/396 (45%), Gaps = 31/396 (7%) Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLV-VSATDSDVGI--NAQITYSLSSE 511 + + I D N+ AP F N PY V E+ I + + V A D D N+++ +S+S+ Sbjct: 165 ITVYIEDVNDNAPEFLNVPYVVDVDENTSIESIIFEGVQAFDRDKPNTPNSEVHFSMST- 223 Query: 512 ISNEAVAHHDQQFVI-NPQTGAITTNKLLDRET-MSGYLLTVTARDGGVPSLSDTTDVEI 569 + + A F + +P + + LD + + + L + A D G P+ T + I Sbjct: 224 VPEQLSADGSPYFALKSPHRPLLILKRELDFDNGIRQFKLPIFAWDRGTPANQANTTITI 283 Query: 570 SVVDVNDNEPVFKQQLYTANIMED-ALVGTSVS-------QVGATDADVGLNGRIHYELD 621 +V DV+D P F + +Y I E + G + + A D D LN + Y++ Sbjct: 284 NVRDVDDLPPKFTEGVYRTRINEFYPMTGVPIRIPLYFAPPIMAFDQD-SLNASLVYDII 342 Query: 622 PKDREEGSFVIDPASGVIRTNKALDRESVA----THDLKAVAIDGGTPPQSSTVIVHIKI 677 E F ++P +GV+ K +D E + T L+ A P + + + +++ Sbjct: 343 -SGNERQLFRVNPHNGVMYLQKEIDLEEESLPGNTFVLQLEARQKDNPLKKALARIEVEV 401 Query: 678 EDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS-IKGGDDSNSFS 736 D+ND+ P FE+D I EN P G ++ ++ A D D+G N+ Y+ ++ D + +F Sbjct: 402 LDLNDNVPEFEADYYNISIVENLPTGFSVLQVNAVDRDQGENSEFLYNLVETKDAAGAFR 461 Query: 737 LETRQG-----SDKA---ELVTMVDLDYES-PRKKYELVIRAASPPLWNDVRVEILVTDV 787 +++R G D+ E + L+ E+ R L + P + V+VEI + D Sbjct: 462 IDSRTGWITVRDDRLLDREQRRSIQLNVEALERNPSYLDDKHLKKPGPSKVQVEITLLDT 521 Query: 788 NDNAPVMKDFQIIFNNYKDCFPVG-PFGRVPAYDAD 822 NDN P + + P G G+V A+D D Sbjct: 522 NDNTPKFEHGNLYEFKVPINAPTGYVIGQVVAHDPD 557 Score = 87.8 bits (208), Expect = 4e-15 Identities = 97/369 (26%), Positives = 160/369 (43%), Gaps = 65/369 (17%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 + V+D N+H+P F+ Y EG + + L A D D G+NA + YT+ +D+ Sbjct: 1271 RFTVMDVNNHAPTFKKSWYSFDTPEGEYKDSVLGQLTAIDMDFGENANITYTL----SDS 1326 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 P F I SG L LDRE +Y+ V ATD A PV R Sbjct: 1327 HLP-----------------FTIKPASGVLKIGGQLDRELKDKYSFQVIATDNA-PVMQR 1368 Query: 130 LSSTATIHVNIIDDNDNYPQF----------------SEKTYTVSVDE---DISVTDNPV 170 +SS+ + VN++D NDN P+F +++T + V + D S Sbjct: 1369 MSSSVDVEVNVLDINDNRPEFIGYDDQTKAVKFIPSVADRTLMLPVYKAYLDRSTQPGTF 1428 Query: 171 IAKIKATDAD-VG-ANSAIRYAIIGGNTQMQ-FSIDSLSGDVSLVKTLD-YEQVRSYRLV 226 + ++ A D D VG N + Y+I Q F IDS G +S + ++ Y + Sbjct: 1429 VRQLTAIDKDNVGNGNGLVLYSIRHQEMQAPLFQIDSRDGTISTISRINGYNDYEHLNVS 1488 Query: 227 IRAQDGGSPSRSNTTQLLINIRD--VND------------NAPRFYTSLFQESVSENVPI 272 + A D GSP+ S T +++N++ V D N F + ++ ++EN Sbjct: 1489 VIASDVGSPALSATAIVIVNLQGQAVTDPPKSTPKPEPPANVTVFQHAYYEVKLTENNEA 1548 Query: 273 GYSIVRVQAYDADEGVNAE-LTYTMTDKDYTGNVDL--PITIDPRSGWVYTSGQLDRETQ 329 ++R+ + G+N E +++ ++ D P D ++ +Y DRE Sbjct: 1549 PIEVMRL---NLSAGLNPENYRWSLWLEEGLDETDAHPPFEYDAKNMLLYALKPFDREHI 1605 Query: 330 AKYQLLVTA 338 ++YQL + A Sbjct: 1606 SRYQLRIRA 1614 Score = 85.0 bits (201), Expect = 3e-14 Identities = 88/341 (25%), Positives = 150/341 (43%), Gaps = 36/341 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++ VLD ND+ P FE Y S+ E +G +VL + A D+D G+N+E Y + Sbjct: 398 EVEVLDLNDNVPEFEADYYNISIVENLPTGFSVLQVNAVDRDQGENSEFLYNL------- 450 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS--LDREKVARYTVLVKATDQ-ASPV 126 + +DA FRID R+G + R LDRE+ + V+A ++ S + Sbjct: 451 VETKDAA-----------GAFRIDSRTGWITVRDDRLLDREQRRSIQLNVEALERNPSYL 499 Query: 127 SDRL-----SSTATIHVNIIDDNDNYPQFSE-KTYTVSVDEDISVTDNPVIAKIKATDAD 180 D+ S + + ++D NDN P+F Y V I+ VI ++ A D D Sbjct: 500 DDKHLKKPGPSKVQVEITLLDTNDNTPKFEHGNLYEFKV--PINAPTGYVIGQVVAHDPD 557 Query: 181 VGANSAIRYAI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRS 238 G N + Y + G+ + F +D+ +G + + L ++ + S R Sbjct: 558 EGPNGHLLYELQRPKGSGYIPFRLDNKNGTIYVGGPLRRGRIAVFVEATDQPTNPSERRF 617 Query: 239 NTTQLLINI-RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297 + + I + ++D A F + ++ V N P+G S+ +V+ EG E+ Y Sbjct: 618 SLAVITIEVYATIDDQAIDFVGAPYEFWVGANTPLGTSVGQVRTTLIYEG-GDEIMY--- 673 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTA 338 D +T + +P I+ RSG + +L + YQ A Sbjct: 674 DLLHTYSEGVPFAIEERSGIITVIRELSEFKRKVYQFEAVA 714 Score = 75.8 bits (178), Expect = 2e-11 Identities = 60/190 (31%), Positives = 87/190 (45%), Gaps = 26/190 (13%) Query: 167 DNPV---IAKIKATDADVGANSAIRYAIIGGNTQMQ-------------FSIDSLSGDVS 210 D PV + ++ A+D D G N+ + Y + G + F+ID LSG++S Sbjct: 1182 DTPVGTKVLQLSASDEDFGKNALLHYELQGEQVERTPGMPMLRVHGVKYFAIDKLSGELS 1241 Query: 211 LVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENV 270 + L L + DG ++T L + DVN++AP F S + E Sbjct: 1242 VNYPLSANIEIMLNLTVTDIDG----LKDSTCLRFTVMDVNNHAPTFKKSWYSFDTPEGE 1297 Query: 271 PIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA 330 + ++ A D D G NA +TYT++D LP TI P SG + GQLDRE + Sbjct: 1298 YKDSVLGQLTAIDMDFGENANITYTLSDSH------LPFTIKPASGVLKIGGQLDRELKD 1351 Query: 331 KYQLLVTATD 340 KY V ATD Sbjct: 1352 KYSFQVIATD 1361 Score = 72.9 bits (171), Expect = 1e-10 Identities = 97/380 (25%), Positives = 157/380 (41%), Gaps = 55/380 (14%) Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 LD ++++ Y L + A D+GG S A + + + D N+ AP+FE SVF+D+ + Sbjct: 1047 LDREKQQLYNLKIIAADTGGLSGYAHLTVLVADVNDNAPMFER----ISVFKDSRL---E 1099 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 + TD ++ + + +++ + A+ + I G+ N +DRE G Sbjct: 1100 IREYTTDMEIYF-VESSSGMTAPQATAAMMLAPPPYHI---PGSPRFN--VDRERSVGAG 1153 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 L V AR + + + + ++ PV GT V Q+ A+D Sbjct: 1154 LGVVARAKSRRRMVRALTTKCPLFAIYEDTPV----------------GTKVLQLSASDE 1197 Query: 609 DVGLNGRIHYELD----------PKDREEG--SFVIDPASGVIRTNKALDRESVATHDLK 656 D G N +HYEL P R G F ID SG + N L +L Sbjct: 1198 DFGKNALLHYELQGEQVERTPGMPMLRVHGVKYFAIDKLSGELSVNYPLSANIEIMLNLT 1257 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE 716 IDG + + + D+N+ P F+ +F E + +G++ A D D Sbjct: 1258 VTDIDG----LKDSTCLRFTVMDVNNHAPTFKKSWYSFDTPEGEYKDSVLGQLTAIDMDF 1313 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW- 775 G NA + Y++ D F+++ G L LD E K VI + P+ Sbjct: 1314 GENANITYTL--SDSHLPFTIKPASG----VLKIGGQLDRELKDKYSFQVIATDNAPVMQ 1367 Query: 776 ---NDVRVEILVTDVNDNAP 792 + V VE+ V D+NDN P Sbjct: 1368 RMSSSVDVEVNVLDINDNRP 1387 Score = 70.9 bits (166), Expect = 5e-10 Identities = 87/345 (25%), Positives = 142/345 (41%), Gaps = 44/345 (12%) Query: 31 SVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDV- 89 ++ E GT VL L A+D+D GKNA + Y ++ E V V Sbjct: 1178 AIYEDTPVGTKVLQLSASDEDFGKNALLHYELQ--------GEQVERTPGMPMLRVHGVK 1229 Query: 90 -FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 F ID SG L L A +++ T + + D L + + ++D N++ P Sbjct: 1230 YFAIDKLSGELSVNYPLS----ANIEIMLNLT--VTDI-DGLKDSTCLRFTVMDVNNHAP 1282 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGD 208 F + Y+ E D+ V+ ++ A D D G N+ I Y + ++ + F+I SG Sbjct: 1283 TFKKSWYSFDTPEG-EYKDS-VLGQLTAIDMDFGENANITYTL--SDSHLPFTIKPASGV 1338 Query: 209 VSLVKTLDYEQVRSYRLVIRAQDGGSPSR--SNTTQLLINIRDVNDNAPRFYTSLFQESV 266 + + LD E Y + A D + S++ + +N+ D+NDN P F Q Sbjct: 1339 LKIGGQLDRELKDKYSFQVIATDNAPVMQRMSSSVDVEVNVLDINDNRPEFIGYDDQTKA 1398 Query: 267 SENVP-IGYSIVRVQAYDA--DEGVNAEL---TYTMTDKDYTGN-------------VDL 307 + +P + + + Y A D T DKD GN + Sbjct: 1399 VKFIPSVADRTLMLPVYKAYLDRSTQPGTFVRQLTAIDKDNVGNGNGLVLYSIRHQEMQA 1458 Query: 308 PI-TIDPRSGWVYTSGQLDRETQAKY-QLLVTATDGGDPPRSATA 350 P+ ID R G + T +++ ++ + V A+D G P SATA Sbjct: 1459 PLFQIDSRDGTISTISRINGYNDYEHLNVSVIASDVGSPALSATA 1503 Score = 62.1 bits (144), Expect = 2e-07 Identities = 76/285 (26%), Positives = 122/285 (42%), Gaps = 27/285 (9%) Query: 532 AITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV--DVNDNEPVFKQQLYTAN 589 A + +L+DR+ L G L + + + I+V DVNDN P F Y + Sbjct: 128 ARSLERLVDRDVPRNLLKFRILCAGKQEKLEEGSYLSITVYIEDVNDNAPEFLNVPYVVD 187 Query: 590 IMEDALVGTSVSQ-VGATDADVGL--NGRIHYELDPKDRE---EGS--FVI-DPASGVIR 640 + E+ + + + + V A D D N +H+ + + +GS F + P ++ Sbjct: 188 VDENTSIESIIFEGVQAFDRDKPNTPNSEVHFSMSTVPEQLSADGSPYFALKSPHRPLLI 247 Query: 641 TNKALDRES-VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISEN 699 + LD ++ + L A D GTP + + I + D++D PP F I+E Sbjct: 248 LKRELDFDNGIRQFKLPIFAWDRGTPANQANTTITINVRDVDDLPPKFTEGVYRTRINEF 307 Query: 700 SPI-GTTIG-------EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTM 751 P+ G I I A D D NA + Y I G++ F + G L Sbjct: 308 YPMTGVPIRIPLYFAPPIMAFDQDS-LNASLVYDIISGNERQLFRVNPHNGV--MYLQKE 364 Query: 752 VDLDYES-PRKKYELVIRAASP--PLWNDV-RVEILVTDVNDNAP 792 +DL+ ES P + L + A PL + R+E+ V D+NDN P Sbjct: 365 IDLEEESLPGNTFVLQLEARQKDNPLKKALARIEVEVLDLNDNVP 409 Score = 60.9 bits (141), Expect = 5e-07 Identities = 93/382 (24%), Positives = 157/382 (41%), Gaps = 53/382 (13%) Query: 10 QINVLDCNDHSPVF-EMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTA- 67 ++NVLD ND+ P F +V+ S L L + ++ + + +TA Sbjct: 1376 EVNVLDINDNRPEFIGYDDQTKAVKFIPSVADRTLMLPVYKAYLDRSTQPGTFVRQLTAI 1435 Query: 68 --DTLNPEDAXXXXXXXXXXVQ-DVFRIDGRSGALLTRASLDR-EKVARYTVLVKATDQA 123 D + + +Q +F+ID R G + T + ++ V V A+D Sbjct: 1436 DKDNVGNGNGLVLYSIRHQEMQAPLFQIDSRDGTISTISRINGYNDYEHLNVSVIASDVG 1495 Query: 124 SPVSDRLSSTATIHVNI----IDDNDNYPQFSEKTYTVSVDE----DISVTDN-PVIAKI 174 SP LS+TA + VN+ + D E V+V + ++ +T+N ++ Sbjct: 1496 SPA---LSATAIVIVNLQGQAVTDPPKSTPKPEPPANVTVFQHAYYEVKLTENNEAPIEV 1552 Query: 175 KATDADVGANSA-------IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVI 227 + G N + + + F D+ + + +K D E + Y+L I Sbjct: 1553 MRLNLSAGLNPENYRWSLWLEEGLDETDAHPPFEYDAKNMLLYALKPFDREHISRYQLRI 1612 Query: 228 RAQDGGSPSRS------------------NTTQLLINIRDVNDNAPRFYTS--LFQESVS 267 RA +R+ N ++L++I D NDNAP+F + + Sbjct: 1613 RADRLSREARNYARVSYPVVDERIEGLSLNECRILVHIADENDNAPKFRGNGQPIVAVLP 1672 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRE 327 ++ GY + RV+A D DEG+NAE+ Y + ++ ID SG + G+L R Sbjct: 1673 QSASFGYPVTRVEANDLDEGLNAEIRYRLLNEPAR-----LFGIDELSGNIRLLGELSR- 1726 Query: 328 TQAKYQLLVTATD--GGDPPRS 347 T+ Y V ATD G D RS Sbjct: 1727 TEHIYGFDVKATDRMGADDGRS 1748 Score = 57.2 bits (132), Expect = 6e-06 Identities = 36/111 (32%), Positives = 56/111 (50%), Gaps = 5/111 (4%) Query: 637 GVIRTNKALDRESVATHDLKAVA-IDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695 G + T LDRE +++L + G + V+IK++D+ND+ P F + Sbjct: 876 GTLLTLTGLDREQQPSYELTVIVEYSTGLVSGAGIYQVNIKVDDVNDNAPKFNALTYVGL 935 Query: 696 ISENSPIGTTIG---EIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS 743 I+EN +GT + I D DEGPNA ++ GD S+ FS+E G+ Sbjct: 936 INENCVVGTELSMNHAILIQDADEGPNAEFRVQLQ-GDYSDEFSIEYVNGT 985 Score = 54.0 bits (124), Expect = 6e-05 Identities = 49/176 (27%), Positives = 80/176 (45%), Gaps = 21/176 (11%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQAS-----------PVSDR----LS-ST 133 F D ++ L DRE ++RY + ++A D+ S PV D LS + Sbjct: 1585 FEYDAKNMLLYALKPFDREHISRYQLRIRA-DRLSREARNYARVSYPVVDERIEGLSLNE 1643 Query: 134 ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIG 193 I V+I D+NDN P+F + S + + +++A D D G N+ IRY ++ Sbjct: 1644 CRILVHIADENDNAPKFRGNGQPIVAVLPQSASFGYPVTRVEANDLDEGLNAEIRYRLLN 1703 Query: 194 GNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQD--GGSPSRSNTTQLLINI 247 ++ F ID LSG++ L+ L + Y ++A D G RS + + I Sbjct: 1704 EPARL-FGIDELSGNIRLLGELSRTE-HIYGFDVKATDRMGADDGRSGIVNVFVYI 1757 Score = 53.2 bits (122), Expect = 1e-04 Identities = 56/212 (26%), Positives = 102/212 (48%), Gaps = 26/212 (12%) Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGE-IRAHDPDE--GPNAVVH 723 + S + + + IED+ND+ P F + + EN+ I + I E ++A D D+ PN+ VH Sbjct: 159 EGSYLSITVYIEDVNDNAPEFLNVPYVVDVDENTSIESIIFEGVQAFDRDKPNTPNSEVH 218 Query: 724 YSIK------GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA---ASPPL 774 +S+ D S F+L++ + L+ +LD+++ ++++L I A +P Sbjct: 219 FSMSTVPEQLSADGSPYFALKS---PHRPLLILKRELDFDNGIRQFKLPIFAWDRGTPAN 275 Query: 775 WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV-GPFGRVP--------AYDAD-VT 824 + + I V DV+D P + + + +P+ G R+P A+D D + Sbjct: 276 QANTTITINVRDVDDLPPKFTE-GVYRTRINEFYPMTGVPIRIPLYFAPPIMAFDQDSLN 334 Query: 825 DKLQYRILSGNNANLILLNETTGSMTLSPQLN 856 L Y I+SGN L +N G M L +++ Sbjct: 335 ASLVYDIISGNERQLFRVNPHNGVMYLQKEID 366 Score = 52.8 bits (121), Expect = 1e-04 Identities = 43/115 (37%), Positives = 58/115 (50%), Gaps = 8/115 (6%) Query: 183 ANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKT--LDYEQVRSYRL-VIRAQDGGSPSRSN 239 AN +RY I N Q + S++ D +L+ LD EQ SY L VI G S + Sbjct: 852 ANIKLRYII--ANQQEVVNKISITEDGTLLTLTGLDREQQPSYELTVIVEYSTGLVSGAG 909 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQA---YDADEGVNAE 291 Q+ I + DVNDNAP+F + ++EN +G + A DADEG NAE Sbjct: 910 IYQVNIKVDDVNDNAPKFNALTYVGLINENCVVGTELSMNHAILIQDADEGPNAE 964 Score = 52.8 bits (121), Expect = 1e-04 Identities = 45/130 (34%), Positives = 58/130 (44%), Gaps = 10/130 (7%) Query: 521 DQQFVINP----QTGAITTNKLLDRETMSGYLLTVTAR-DGGVPSLSDTTDVEISVVDVN 575 +QQ V+N + G + T LDRE Y LTV G+ S + V I V DVN Sbjct: 862 NQQEVVNKISITEDGTLLTLTGLDREQQPSYELTVIVEYSTGLVSGAGIYQVNIKVDDVN 921 Query: 576 DNEPVFKQQLYTANIMEDALVGTSVSQVGA---TDADVGLNGRIHYELDPKDREEGSFVI 632 DN P F Y I E+ +VGT +S A DAD G N +L +E F I Sbjct: 922 DNAPKFNALTYVGLINENCVVGTELSMNHAILIQDADEGPNAEFRVQLQGDYSDE--FSI 979 Query: 633 DPASGVIRTN 642 + +G N Sbjct: 980 EYVNGTSSEN 989 Score = 49.6 bits (113), Expect = 0.001 Identities = 36/115 (31%), Positives = 57/115 (49%), Gaps = 4/115 (3%) Query: 97 GALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYT 156 G LLT LDRE+ Y + V VS + +++ + D NDN P+F+ TY Sbjct: 876 GTLLTLTGLDREQQPSYELTVIVEYSTGLVSG--AGIYQVNIKVDDVNDNAPKFNALTYV 933 Query: 157 VSVDEDISV-TDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVS 210 ++E+ V T+ + I DAD G N+ R + G + +FSI+ ++G S Sbjct: 934 GLINENCVVGTELSMNHAILIQDADEGPNAEFRVQLQGDYSD-EFSIEYVNGTSS 987 Score = 48.8 bits (111), Expect = 0.002 Identities = 113/548 (20%), Positives = 206/548 (37%), Gaps = 77/548 (14%) Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPI---------TIDPRS 315 ++ E+ P+G ++++ A D D G NA L Y + + +P+ ID S Sbjct: 1178 AIYEDTPVGTKVLQLSASDEDFGKNALLHYELQGEQVERTPGMPMLRVHGVKYFAIDKLS 1237 Query: 316 GWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVEL 375 G + + L + L VT DG + F Y + Sbjct: 1238 GELSVNYPLSANIEIMLNLTVTDIDG----LKDSTCLRFTVMDVNNHAPTFKKSWYSFDT 1293 Query: 376 AEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435 E E + + LTA D D + T ++ F+I + G++ + LD + + Sbjct: 1294 PEGEYKDSVLGQLTAIDMDFGENANITYTLSDSHLPFTI--KPASGVLKIGGQLDRELKD 1351 Query: 436 RYVLTVSATDSG----GRSDTAMVQINITDANNYAPVF---ENAPYTASVFEDAPIGTTV 488 +Y V ATD+ S + V++N+ D N+ P F ++ T + Sbjct: 1352 KYSFQVIATDNAPVMQRMSSSVDVEVNVLDINDNRPEFIGYDDQTKAVKFIPSVADRTLM 1411 Query: 489 LVVSATDSDVGIN-----AQITYSLSSEISN------EAVAHHDQQ---FVINPQTGAIT 534 L V D Q+T + N ++ H + Q F I+ + G I+ Sbjct: 1412 LPVYKAYLDRSTQPGTFVRQLTAIDKDNVGNGNGLVLYSIRHQEMQAPLFQIDSRDGTIS 1471 Query: 535 TNKLLDRETMSGYL-LTVTARDGGVPSLSDTTDVEI-----SVVDVNDNEP--------- 579 T ++ +L ++V A D G P+LS T V + +V D + P Sbjct: 1472 TISRINGYNDYEHLNVSVIASDVGSPALSATAIVIVNLQGQAVTDPPKSTPKPEPPANVT 1531 Query: 580 VFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGR----IHYELDPKDREEGSFVIDPA 635 VF+ Y + E+ V ++ + N R + LD D F D Sbjct: 1532 VFQHAYYEVKLTENNEAPIEVMRLNLSAGLNPENYRWSLWLEEGLDETDAHP-PFEYDAK 1590 Query: 636 SGVIRTNKALDRESVATHDLK----AVAIDGGTPPQSSTVIVHIKIE------------- 678 + ++ K DRE ++ + L+ ++ + + S +V +IE Sbjct: 1591 NMLLYALKPFDREHISRYQLRIRADRLSREARNYARVSYPVVDERIEGLSLNECRILVHI 1650 Query: 679 -DINDSPPVFESD--CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735 D ND+ P F + + + +++ G + + A+D DEG NA + Y + + + F Sbjct: 1651 ADENDNAPKFRGNGQPIVAVLPQSASFGYPVTRVEANDLDEGLNAEIRYRLL-NEPARLF 1709 Query: 736 SLETRQGS 743 ++ G+ Sbjct: 1710 GIDELSGN 1717 Score = 46.4 bits (105), Expect = 0.011 Identities = 41/196 (20%), Positives = 81/196 (41%), Gaps = 7/196 (3%) Query: 691 CLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLE-TRQGSDKAELV 749 C F I E++P+GT + ++ A D D G NA++HY ++G + + R K + Sbjct: 1174 CPLFAIYEDTPVGTKVLQLSASDEDFGKNALLHYELQGEQVERTPGMPMLRVHGVKYFAI 1233 Query: 750 TMV--DLDYESP-RKKYELVIRAASPP---LWNDVRVEILVTDVNDNAPVMKDFQIIFNN 803 + +L P E+++ L + + V DVN++AP K F+ Sbjct: 1234 DKLSGELSVNYPLSANIEIMLNLTVTDIDGLKDSTCLRFTVMDVNNHAPTFKKSWYSFDT 1293 Query: 804 YKDCFPVGPFGRVPAYDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLA 863 + + G++ A D D + ++ + +G + + QL+ + Sbjct: 1294 PEGEYKDSVLGQLTAIDMDFGENANITYTLSDSHLPFTIKPASGVLKIGGQLDRELKDKY 1353 Query: 864 TMEVSVTDGVNEIKAM 879 + +V TD ++ M Sbjct: 1354 SFQVIATDNAPVMQRM 1369 Score = 42.7 bits (96), Expect = 0.14 Identities = 38/129 (29%), Positives = 57/129 (44%), Gaps = 10/129 (7%) Query: 394 DEDNRLHYEITGGN-TRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR-SD 451 D + +L Y I + SIT G + LD +Q+ Y LTV S G S Sbjct: 851 DANIKLRYIIANQQEVVNKISITED---GTLLTLTGLDREQQPSYELTVIVEYSTGLVSG 907 Query: 452 TAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTVLV---VSATDSDVGINAQITY 506 + Q+NI D N+ AP F Y + E+ +GT + + + D+D G NA+ Sbjct: 908 AGIYQVNIKVDDVNDNAPKFNALTYVGLINENCVVGTELSMNHAILIQDADEGPNAEFRV 967 Query: 507 SLSSEISNE 515 L + S+E Sbjct: 968 QLQGDYSDE 976 >UniRef50_UPI000065EA0C Cluster: Cadherin-20 precursor.; n=1; Takifugu rubripes|Rep: Cadherin-20 precursor. - Takifugu rubripes Length = 878 Score = 156 bits (378), Expect = 9e-36 Identities = 109/349 (31%), Positives = 176/349 (50%), Gaps = 28/349 (8%) Query: 391 TDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSA----TD 445 +D D+ D + Y +TG F+I G I Q LD + + +YVL A TD Sbjct: 37 SDMDKGDGSIKYILTGEGAGTTFTIDDNTGD--IHAIQRLDREMKAQYVLRAQARNRLTD 94 Query: 446 SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505 ++ + + I D N+ P F + PY A+V E + IGT+V+ ++ATD+D T Sbjct: 95 RPLEPESEFI-VKIQDINDNEPRFLDGPYWATVPEMSQIGTSVIQLTATDAD-----DPT 148 Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGAITTNKL-LDRETMSGYLLTVTARD--GGVPSLS 562 Y S+ + ++ F ++ +TG + + +DRET Y + + A+D G + L+ Sbjct: 149 YGNSARVVY-SILEGQPYFSVDAKTGVLRVSLADMDRETRENYSVVIQAKDMGGQMGGLA 207 Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL-D 621 TT V I++ D+NDN P+F Q+LY +I E A +G+ V ++ A D D+G+N + Y + D Sbjct: 208 GTTTVNITLTDINDNPPMFDQRLYQMSIPEAAPMGSVVGRIWAKDRDIGINAEMRYSIID 267 Query: 622 PKDREEGSFVIDPAS--GVIRTNKALDRESVATHDLKAVAIDGGTPPQ-------SSTVI 672 R+ DP + G+I K LD E+ ++ LK + P I Sbjct: 268 GDGRDTFDVSTDPTNLFGIITVKKPLDFETKPSYTLKVEGANTQVDPLFHHHGPFKDVTI 327 Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV 721 VH+ +ED+ D PP+F+S + E++ IGT + + A DPD N V Sbjct: 328 VHVSVEDV-DEPPLFDSPGYYIELPEDAEIGTVVKTVSARDPDSANNTV 375 Score = 144 bits (349), Expect = 3e-32 Identities = 161/626 (25%), Positives = 276/626 (44%), Gaps = 78/626 (12%) Query: 177 TDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG-GSP 235 +D D G S I+Y + G F+ID +GD+ ++ LD E Y L +A++ Sbjct: 37 SDMDKGDGS-IKYILTGEGAGTTFTIDDNTGDIHAIQRLDREMKAQYVLRAQARNRLTDR 95 Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE---GVNAEL 292 ++ ++ I+D+NDN PRF + +V E IG S++++ A DAD+ G +A + Sbjct: 96 PLEPESEFIVKIQDINDNEPRFLDGPYWATVPEMSQIGTSVIQLTATDADDPTYGNSARV 155 Query: 293 TYTMTD-KDYTGNVDLPITIDPRSGWVYTS-GQLDRETQAKYQLLVTATD-GGDPPRSA- 348 Y++ + + Y ++D ++G + S +DRET+ Y +++ A D GG A Sbjct: 156 VYSILEGQPY-------FSVDAKTGVLRVSLADMDRETRENYSVVIQAKDMGGQMGGLAG 208 Query: 349 TATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGG 406 T T F Y++ + E P G+ V + A D D + + Y I G Sbjct: 209 TTTVNITLTDINDNPPMFDQRLYQMSIPEAAPMGSVVGRIWAKDRDIGINAEMRYSIIDG 268 Query: 407 NTRGRFSITSQ--NGRGLITVAQPLDFKQERRYVLTVSATDS---------GGRSDTAMV 455 + R F +++ N G+ITV +PLDF+ + Y L V ++ G D +V Sbjct: 269 DGRDTFDVSTDPTNLFGIITVKKPLDFETKPSYTLKVEGANTQVDPLFHHHGPFKDVTIV 328 Query: 456 QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNE 515 +++ D + P+F++ Y + EDA IGT V VSA D D N S ++ N Sbjct: 329 HVSVEDVDE-PPLFDSPGYYIELPEDAEIGTVVKTVSARDPDSANNT--VRSPPQDVIN- 384 Query: 516 AVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISV-VDV 574 + Q+ + + +T E ++G L V GGV + D + + + + Sbjct: 385 --CYTTQRLKVKER--LVTLTGYTRAEMVNG--LVVLGLGGGVVLIKTINDYALRLSLRL 438 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRI------HYELDPKDREEG 628 + V +Q + + TS ++ GA + +NG + Y ++ + + Sbjct: 439 SIIWGVGQQAAASLSGF------TSWNRDGAGGWEALMNGCMCCFGVCRYSIERTNDLDK 492 Query: 629 SFVIDPASGVIRTNKALDRESVATHDLKAVAID------------GGT------------ 664 F ID SG + T + LDRE ++ H++ +A++ G+ Sbjct: 493 YFYIDITSGALMTVRTLDREEMSWHNITVLAMEMRLGPGKWTLAPSGSLVIRVCVCVSTD 552 Query: 665 -PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 P Q ++V V IKI D+ND+PP + L Y+ EN+ G I + A D DE Sbjct: 553 NPSQIASVSVAIKITDVNDNPPSL-THYLEAYVCENAKAGQLIQMVTAVDVDEPQGGQHF 611 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELV 749 Y + +N+ + R D V Sbjct: 612 YYSLAPEAANNPNFTLRDNQDNTAWV 637 Score = 124 bits (300), Expect = 3e-26 Identities = 106/324 (32%), Positives = 159/324 (49%), Gaps = 26/324 (8%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR-LSSTATIHVNIIDDNDNYP 148 F ID +G + LDRE A+Y + +A ++ ++DR L + V I D NDN P Sbjct: 59 FTIDDNTGDIHAIQRLDREMKAQYVLRAQARNR---LTDRPLEPESEFIVKIQDINDNEP 115 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDAD---VGANSAIRYAIIGGNTQMQFSIDSL 205 +F + Y +V E +S VI ++ ATDAD G ++ + Y+I+ G Q FS+D+ Sbjct: 116 RFLDGPYWATVPE-MSQIGTSVI-QLTATDADDPTYGNSARVVYSILEG--QPYFSVDAK 171 Query: 206 SGDVSL-VKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQLLINIRDVNDNAPRFYTSLF 262 +G + + + +D E +Y +VI+A+D G + TT + I + D+NDN P F L+ Sbjct: 172 TGVLRVSLADMDRETRENYSVVIQAKDMGGQMGGLAGTTTVNITLTDINDNPPMFDQRLY 231 Query: 263 QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS--GWVYT 320 Q S+ E P+G + R+ A D D G+NAE+ Y++ D D G ++ DP + G + Sbjct: 232 QMSIPEAAPMGSVVGRIWAKDRDIGINAEMRYSIIDGD--GRDTFDVSTDPTNLFGIITV 289 Query: 321 SGQLDRETQAKYQLLVT-ATDGGDP------PRSATATXXXXXXXXXXXXXXFMPGQYEV 373 LD ET+ Y L V A DP P PG Y + Sbjct: 290 KKPLDFETKPSYTLKVEGANTQVDPLFHHHGPFKDVTIVHVSVEDVDEPPLFDSPGYY-I 348 Query: 374 ELAEDEPPGTPVVTLTATDADEDN 397 EL ED GT V T++A D D N Sbjct: 349 ELPEDAEIGTVVKTVSARDPDSAN 372 Score = 120 bits (290), Expect = 4e-25 Identities = 84/255 (32%), Positives = 131/255 (51%), Gaps = 11/255 (4%) Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFK 582 F I+ TG I + LDRE + Y+L AR+ L ++ + + D+NDNEP F Sbjct: 59 FTIDDNTGDIHAIQRLDREMKAQYVLRAQARNRLTDRPLEPESEFIVKIQDINDNEPRFL 118 Query: 583 QQLYTANIMEDALVGTSVSQVGATDAD---VGLNGRIHYELDPKDREEGSFVIDPASGVI 639 Y A + E + +GTSV Q+ ATDAD G + R+ Y + + F +D +GV+ Sbjct: 119 DGPYWATVPEMSQIGTSVIQLTATDADDPTYGNSARVVYSIL---EGQPYFSVDAKTGVL 175 Query: 640 RTNKA-LDRESVATHDLKAVAID--GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696 R + A +DRE+ + + A D G + T V+I + DIND+PP+F+ I Sbjct: 176 RVSLADMDRETRENYSVVIQAKDMGGQMGGLAGTTTVNITLTDINDNPPMFDQRLYQMSI 235 Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756 E +P+G+ +G I A D D G NA + YSI GD ++F + T + + LD+ Sbjct: 236 PEAAPMGSVVGRIWAKDRDIGINAEMRYSIIDGDGRDTFDVSTDPTNLFGIITVKKPLDF 295 Query: 757 ESPRKKYELVIRAAS 771 E+ + Y L + A+ Sbjct: 296 ET-KPSYTLKVEGAN 309 Score = 102 bits (245), Expect = 1e-19 Identities = 85/294 (28%), Positives = 140/294 (47%), Gaps = 40/294 (13%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVTA 67 + + D ND+ P F Y A+V E + GT+V+ L ATD D G +A V Y+I Sbjct: 105 VKIQDINDNEPRFLDGPYWATVPEMSQIGTSVIQLTATDADDPTYGNSARVVYSI----- 159 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLVKATDQASPV 126 Q F +D ++G L ++ A +DRE Y+V+++A D + Sbjct: 160 ----------------LEGQPYFSVDAKTGVLRVSLADMDRETRENYSVVIQAKDMGGQM 203 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 L+ T T+++ + D NDN P F ++ Y +S+ E + V+ +I A D D+G N+ Sbjct: 204 GG-LAGTTTVNITLTDINDNPPMFDQRLYQMSIPE--AAPMGSVVGRIWAKDRDIGINAE 260 Query: 187 IRYAIIGGNTQMQFSID----SLSGDVSLVKTLDYEQVRSYRLVIR-AQDGGSP------ 235 +RY+II G+ + F + +L G +++ K LD+E SY L + A P Sbjct: 261 MRYSIIDGDGRDTFDVSTDPTNLFGIITVKKPLDFETKPSYTLKVEGANTQVDPLFHHHG 320 Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVN 289 + T + +++ DV D P F + + + E+ IG + V A D D N Sbjct: 321 PFKDVTIVHVSVEDV-DEPPLFDSPGYYIELPEDAEIGTVVKTVSARDPDSANN 373 Score = 80.2 bits (189), Expect = 8e-13 Identities = 79/245 (32%), Positives = 124/245 (50%), Gaps = 27/245 (11%) Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVA----ID 661 +D D G +G I Y L + +F ID +G I + LDRE A + L+A A D Sbjct: 37 SDMDKG-DGSIKYILTGEGAGT-TFTIDDNTGDIHAIQRLDREMKAQYVLRAQARNRLTD 94 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE---GP 718 P+S ++ KI+DIND+ P F + E S IGT++ ++ A D D+ G Sbjct: 95 RPLEPESEFIV---KIQDINDNEPRFLDGPYWATVPEMSQIGTSVIQLTATDADDPTYGN 151 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP----- 773 +A V YSI G FS++ + G + V++ D+D E+ R+ Y +VI+A Sbjct: 152 SARVVYSILEGQPY--FSVDAKTGVLR---VSLADMDRET-RENYSVVIQAKDMGGQMGG 205 Query: 774 LWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGP-FGRVPAYDAD--VTDKLQYR 830 L V I +TD+NDN P M D ++ + + P+G GR+ A D D + +++Y Sbjct: 206 LAGTTTVNITLTDINDNPP-MFDQRLYQMSIPEAAPMGSVVGRIWAKDRDIGINAEMRYS 264 Query: 831 ILSGN 835 I+ G+ Sbjct: 265 IIDGD 269 Score = 61.7 bits (143), Expect = 3e-07 Identities = 51/182 (28%), Positives = 83/182 (45%), Gaps = 23/182 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I + D ND+ P+F+ + Y+ S+ E A G+ V + A D+DIG NAE+ Y+I + D Sbjct: 214 ITLTDINDNPPMFDQRLYQMSIPEAAPMGSVVGRIWAKDRDIGINAEMRYSI--IDGDGR 271 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVK-ATDQASPVSDR 129 + D ++F G + + LD E YT+ V+ A Q P+ Sbjct: 272 DTFDVSTDPT-------NLF------GIITVKKPLDFETKPSYTLKVEGANTQVDPLFHH 318 Query: 130 ---LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 +HV+ ++D D P F Y + + ED + V+ + A D D AN+ Sbjct: 319 HGPFKDVTIVHVS-VEDVDEPPLFDSPGYYIELPEDAEI--GTVVKTVSARDPD-SANNT 374 Query: 187 IR 188 +R Sbjct: 375 VR 376 Score = 40.7 bits (91), Expect = 0.57 Identities = 30/109 (27%), Positives = 46/109 (42%), Gaps = 3/109 (2%) Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293 +PS+ + + I I DVNDN P T + V EN G I V A D DE + Sbjct: 553 NPSQIASVSVAIKITDVNDNPPSL-THYLEAYVCENAKAGQLIQMVTAVDVDEPQGGQHF 611 Query: 294 YTMTDKDYTGNVDLPITID-PRSGWVYT-SGQLDRETQAKYQLLVTATD 340 Y + N + + + + WV T G ++ Q + L + +D Sbjct: 612 YYSLAPEAANNPNFTLRDNQDNTAWVLTRRGGWSQQQQTVFHLPIIISD 660 >UniRef50_UPI0000E81ECF Cluster: PREDICTED: similar to protocadherin beta 20; n=2; Gallus gallus|Rep: PREDICTED: similar to protocadherin beta 20 - Gallus gallus Length = 808 Score = 155 bits (376), Expect = 2e-35 Identities = 121/387 (31%), Positives = 189/387 (48%), Gaps = 18/387 (4%) Query: 410 GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM---VQINITDANNYA 466 GR + G G + VA+ LD ++ T + +D +++++ D N+++ Sbjct: 226 GRQHFRLERGSGRLVVAERLDREEMCGRSRTCTLAFELLLADPLQFFPIEVSVEDINDHS 285 Query: 467 PVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVI 526 PVF + T + E + GT V +A D D+G N YS+ E NE Q Sbjct: 286 PVFPDERVTFKIPETSDPGTRFPVGAAQDLDIGSNDIQAYSIIPE--NEFFTVFTQSE-- 341 Query: 527 NPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLY 586 + + + K LDRE S T+ A DGG P + +T++ I V+D+NDN PVF Q+LY Sbjct: 342 SSKYVELVLEKPLDREEQSELDFTLVATDGGSPPRTGSTEIHIVVLDINDNVPVFTQKLY 401 Query: 587 TANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGS-FVIDPASGVIRTNKAL 645 +++E+A G+ V +V A DAD G+NG I Y+ S F I+ +G I K L Sbjct: 402 IGHVLENAPEGSVVLRVVANDADEGVNGDISYQFSQSAGHSHSLFTINSRTGEIVIAKPL 461 Query: 646 DRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 D E+ H+ AIDGG SS V +++ D+ND+ P I EN GT Sbjct: 462 DFETAQKHEFTVQAIDGG--GFSSMCNVVVEVLDVNDNAPEIAVTSFNSPILENVEPGTV 519 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYEL 765 + + D D G N + ++ ++ F+L + ELVT+ LD E R ++ + Sbjct: 520 VALLAVSDQDSGVNGEITCAL---EEQLYFALRP-AFKNYYELVTVSTLDREE-RAQHMV 574 Query: 766 VIRAA---SPPLWNDVRVEILVTDVND 789 V+ AA SPPL + + ++DVN+ Sbjct: 575 VVTAADAGSPPLTSTHTFSVDISDVNE 601 Score = 149 bits (360), Expect = 1e-33 Identities = 107/347 (30%), Positives = 167/347 (48%), Gaps = 35/347 (10%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 +++V D NDHSPVF ++ + E + GT A D DIG N + A + Sbjct: 275 EVSVEDINDHSPVFPDERVTFKIPETSDPGTRFPVGAAQDLDIGSND--------IQAYS 326 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + PE+ + V L+ LDRE+ + + ATD SP R Sbjct: 327 IIPENEFFTVFTQSESSKYV--------ELVLEKPLDREEQSELDFTLVATDGGSP--PR 376 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 ST IH+ ++D NDN P F++K Y V E + + V+ ++ A DAD G N I Y Sbjct: 377 TGST-EIHIVVLDINDNVPVFTQKLYIGHVLE--NAPEGSVVLRVVANDADEGVNGDISY 433 Query: 190 AI--IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 G++ F+I+S +G++ + K LD+E + + ++A DGG S+ +++ + Sbjct: 434 QFSQSAGHSHSLFTINSRTGEIVIAKPLDFETAQKHEFTVQAIDGG--GFSSMCNVVVEV 491 Query: 248 RDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDL 307 DVNDNAP + F + ENV G + + D D GVN E+T + ++ Y Sbjct: 492 LDVNDNAPEIAVTSFNSPILENVEPGTVVALLAVSDQDSGVNGEITCALEEQLY------ 545 Query: 308 PITIDPRSGWVY---TSGQLDRETQAKYQLLVTATDGGDPPRSATAT 351 + P Y T LDRE +A++ ++VTA D G PP ++T T Sbjct: 546 -FALRPAFKNYYELVTVSTLDREERAQHMVVVTAADAGSPPLTSTHT 591 Score = 145 bits (351), Expect = 2e-32 Identities = 104/318 (32%), Positives = 153/318 (48%), Gaps = 19/318 (5%) Query: 374 ELAEDEPPGT--PVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGL-ITVAQPLD 430 ++ E PGT PV D ++ Y I N S++ + + + + +PLD Sbjct: 296 KIPETSDPGTRFPVGAAQDLDIGSNDIQAYSIIPENEFFTVFTQSESSKYVELVLEKPLD 355 Query: 431 FKQERRYVLTVSATDSGGRSDTAMVQINIT--DANNYAPVFENAPYTASVFEDAPIGTTV 488 +++ T+ ATD G T +I+I D N+ PVF Y V E+AP G+ V Sbjct: 356 REEQSELDFTLVATDGGSPPRTGSTEIHIVVLDINDNVPVFTQKLYIGHVLENAPEGSVV 415 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYL 548 L V A D+D G+N I+Y S ++ H F IN +TG I K LD ET + Sbjct: 416 LRVVANDADEGVNGDISYQFS-----QSAGHSHSLFTINSRTGEIVIAKPLDFETAQKHE 470 Query: 549 LTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDA 608 TV A DGG S +V + V+DVNDN P + + I+E+ GT V+ + +D Sbjct: 471 FTVQAIDGG--GFSSMCNVVVEVLDVNDNAPEIAVTSFNSPILENVEPGTVVALLAVSDQ 528 Query: 609 DVGLNGRIHYELDPKDREEGSFVIDPASG---VIRTNKALDRESVATHDLKAVAIDGGTP 665 D G+NG I L+ E+ F + PA + T LDRE A H + A D G+P Sbjct: 529 DSGVNGEITCALE----EQLYFALRPAFKNYYELVTVSTLDREERAQHMVVVTAADAGSP 584 Query: 666 PQSSTVIVHIKIEDINDS 683 P +ST + I D+N++ Sbjct: 585 PLTSTHTFSVDISDVNEA 602 Score = 134 bits (325), Expect = 3e-29 Identities = 96/345 (27%), Positives = 156/345 (45%), Gaps = 25/345 (7%) Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 +++ D+ND++P F + E G A D D G N Y++ ++ Sbjct: 276 VSVEDINDHSPVFPDERVTFKIPETSDPGTRFPVGAAQDLDIGSNDIQAYSIIPENEFFT 335 Query: 305 VDLPITIDPRSGWV--YTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXX 362 V T S +V LDRE Q++ + ATDGG PPR+ + Sbjct: 336 V---FTQSESSKYVELVLEKPLDREEQSELDFTLVATDGGSPPRTGSTEIHIVVLDINDN 392 Query: 363 XXXFMPGQYEVELAEDEPPGTPVVTLTATDADE----DNRLHYEITGGNTRGRFSITSQN 418 F Y + E+ P G+ V+ + A DADE D + + G++ F+I S+ Sbjct: 393 VPVFTQKLYIGHVLENAPEGSVVLRVVANDADEGVNGDISYQFSQSAGHSHSLFTINSRT 452 Query: 419 GRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASV 478 G I +A+PLDF+ +++ TV A D GG S V + + D N+ AP + + + Sbjct: 453 GE--IVIAKPLDFETAQKHEFTVQAIDGGGFSSMCNVVVEVLDVNDNAPEIAVTSFNSPI 510 Query: 479 FEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP---QTGAITT 535 E+ GT V +++ +D D G+N +IT +L ++ F + P + T Sbjct: 511 LENVEPGTVVALLAVSDQDSGVNGEITCALEEQL----------YFALRPAFKNYYELVT 560 Query: 536 NKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVND-NEP 579 LDRE + +++ VTA D G P L+ T + + DVN+ EP Sbjct: 561 VSTLDREERAQHMVVVTAADAGSPPLTSTHTFSVDISDVNEATEP 605 Score = 134 bits (324), Expect = 3e-29 Identities = 119/384 (30%), Positives = 187/384 (48%), Gaps = 23/384 (5%) Query: 90 FRIDGRSGALLTRASLDREKVA-RYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 FR++ SG L+ LDRE++ R A + ++D L I V++ D ND+ P Sbjct: 230 FRLERGSGRLVVAERLDREEMCGRSRTCTLAFELL--LADPLQFFP-IEVSVEDINDHSP 286 Query: 149 QFSEKTYTVSVDEDISV-TDNPVIAKIKATDADVGANSAIRYAIIGGN---TQMQFSIDS 204 F ++ T + E T PV A A D D+G+N Y+II N T S S Sbjct: 287 VFPDERVTFKIPETSDPGTRFPVGA---AQDLDIGSNDIQAYSIIPENEFFTVFTQSESS 343 Query: 205 LSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 ++ L K LD E+ + A DGGSP R+ +T++ I + D+NDN P F L+ Sbjct: 344 KYVELVLEKPLDREEQSELDFTLVATDGGSPPRTGSTEIHIVVLDINDNVPVFTQKLYIG 403 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 V EN P G ++RV A DADEGVN +++Y + G+ TI+ R+G + + L Sbjct: 404 HVLENAPEGSVVLRVVANDADEGVNGDISYQFSQS--AGHSHSLFTINSRTGEIVIAKPL 461 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 D ET K++ V A DGG S+ + + E+ PGT Sbjct: 462 DFETAQKHEFTVQAIDGGG--FSSMCNVVVEVLDVNDNAPEIAVTSFNSPILENVEPGT- 518 Query: 385 VVTLTATDADEDNRLHYEITGG-NTRGRFSI--TSQNGRGLITVAQPLDFKQERRYVLTV 441 VV L A +D+D+ ++ EIT + F++ +N L+TV+ LD ++ ++++ V Sbjct: 519 VVALLAV-SDQDSGVNGEITCALEEQLYFALRPAFKNYYELVTVS-TLDREERAQHMVVV 576 Query: 442 SATDSGG--RSDTAMVQINITDAN 463 +A D+G + T ++I+D N Sbjct: 577 TAADAGSPPLTSTHTFSVDISDVN 600 Score = 134 bits (323), Expect = 4e-29 Identities = 101/326 (30%), Positives = 158/326 (48%), Gaps = 17/326 (5%) Query: 473 PYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGA 532 P SV E+ G+ V V+ D G+ + + I++ A H F + +G Sbjct: 185 PIRYSVAEEGESGSVVADVA---EDAGLAPAQLSARRARIASPAGRQH---FRLERGSGR 238 Query: 533 ITTNKLLDRETMSGYLLTVT-ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIM 591 + + LDRE M G T T A + + +E+SV D+ND+ PVF + T I Sbjct: 239 LVVAERLDREEMCGRSRTCTLAFELLLADPLQFFPIEVSVEDINDHSPVFPDERVTFKIP 298 Query: 592 EDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRT--NKALDRES 649 E + GT A D D+G N Y + P++ F +S + K LDRE Sbjct: 299 ETSDPGTRFPVGAAQDLDIGSNDIQAYSIIPENEFFTVFTQSESSKYVELVLEKPLDREE 358 Query: 650 VATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEI 709 + D VA DGG+PP++ + +HI + DIND+ PVF ++ EN+P G+ + + Sbjct: 359 QSELDFTLVATDGGSPPRTGSTEIHIVVLDINDNVPVFTQKLYIGHVLENAPEGSVVLRV 418 Query: 710 RAHDPDEGPNAVVHY--SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI 767 A+D DEG N + Y S G + F++ +R G E+V LD+E+ +K +E + Sbjct: 419 VANDADEGVNGDISYQFSQSAGHSHSLFTINSRTG----EIVIAKPLDFETAQK-HEFTV 473 Query: 768 RAASPPLWNDV-RVEILVTDVNDNAP 792 +A ++ + V + V DVNDNAP Sbjct: 474 QAIDGGGFSSMCNVVVEVLDVNDNAP 499 Score = 86.6 bits (205), Expect = 9e-15 Identities = 67/245 (27%), Positives = 110/245 (44%), Gaps = 30/245 (12%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTL 70 I VLD ND+ PVF + Y V E A G+ VL + A D D G N ++ Y + Sbjct: 384 IVVLDINDNVPVFTQKLYIGHVLENAPEGSVVLRVVANDADEGVNGDISYQFSQSAGHS- 442 Query: 71 NPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRL 130 +F I+ R+G ++ LD E ++ V+A D Sbjct: 443 ----------------HSLFTINSRTGEIVIAKPLDFETAQKHEFTVQAIDGGG-----F 481 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYA 190 SS + V ++D NDN P+ + ++ + E++ V+A + +D D G N I A Sbjct: 482 SSMCNVVVEVLDVNDNAPEIAVTSFNSPILENVE--PGTVVALLAVSDQDSGVNGEITCA 539 Query: 191 IIGGNTQMQFSIDSLSG---DVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINI 247 + Q+ F++ ++ V TLD E+ + +V+ A D GSP ++T ++I Sbjct: 540 L---EEQLYFALRPAFKNYYELVTVSTLDREERAQHMVVVTAADAGSPPLTSTHTFSVDI 596 Query: 248 RDVND 252 DVN+ Sbjct: 597 SDVNE 601 Score = 83.0 bits (196), Expect = 1e-13 Identities = 84/296 (28%), Positives = 131/296 (44%), Gaps = 18/296 (6%) Query: 589 NIMEDALVGTSVSQVGATDADVG---LNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645 ++ E+ G+ V+ V A DA + L+ R P R+ F ++ SG + + L Sbjct: 189 SVAEEGESGSVVADV-AEDAGLAPAQLSARRARIASPAGRQH--FRLERGSGRLVVAERL 245 Query: 646 DRESVATHDLKA-VAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 DRE + +A + + + +EDIND PVF + +TF I E S GT Sbjct: 246 DREEMCGRSRTCTLAFELLLADPLQFFPIEVSVEDINDHSPVFPDERVTFKIPETSDPGT 305 Query: 705 TIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK-AELVTMVDLDYESPRK-K 762 A D D G N + YSI ++ F++ T+ S K ELV LD E + Sbjct: 306 RFPVGAAQDLDIGSNDIQAYSII--PENEFFTVFTQSESSKYVELVLEKPLDREEQSELD 363 Query: 763 YELVIR-AASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYD 820 + LV SPP + I+V D+NDN PV ++ + + P G RV A D Sbjct: 364 FTLVATDGGSPPRTGSTEIHIVVLDINDNVPVFTQ-KLYIGHVLENAPEGSVVLRVVAND 422 Query: 821 AD--VTDKLQYRI--LSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 AD V + Y+ +G++ +L +N TG + ++ L+ + V DG Sbjct: 423 ADEGVNGDISYQFSQSAGHSHSLFTINSRTGEIVIAKPLDFETAQKHEFTVQAIDG 478 >UniRef50_P12830 Cluster: Epithelial cadherin precursor (E-cadherin) (Uvomorulin) (Cadherin-1) (CAM 120/80) (CD324 antigen) [Contains: E-Cad/CTF1; E-Cad/CTF2; E- Cad/CTF3]; n=52; Tetrapoda|Rep: Epithelial cadherin precursor (E-cadherin) (Uvomorulin) (Cadherin-1) (CAM 120/80) (CD324 antigen) [Contains: E-Cad/CTF1; E-Cad/CTF2; E- Cad/CTF3] - Homo sapiens (Human) Length = 882 Score = 154 bits (373), Expect = 4e-35 Identities = 122/401 (30%), Positives = 189/401 (47%), Gaps = 31/401 (7%) Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259 F I+ +G + + + LD E++ +Y L A + + ++LI + D NDN P F Sbjct: 205 FIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQ 264 Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGV---NAELTYTMTDKDYTGNVDLPITIDPRSG 316 +F+ SV E G S++ V A DAD+ V NA + YT+ +D TI+ +G Sbjct: 265 EVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTG 324 Query: 317 --WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374 V T+G LDRE+ Y L+V A D S TAT F P Y+ + Sbjct: 325 VISVVTTG-LDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQ 383 Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITG---GNTRGRFSITSQ--NGRGLITVAQPL 429 + E+E + TL TDAD N +E + G+F +T+ N G++ A+ L Sbjct: 384 VPENE-ANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGL 442 Query: 430 DFKQERRYVLTVSAT-----DSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 DF+ +++Y+L V+ T + + TA V +++ D N AP+F V ED + Sbjct: 443 DFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNE-APIFVPPEKRVEVSEDFGV 501 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 G + +A + D + +ITY + + +N INP TGAI+T LDRE Sbjct: 502 GQEITSYTAQEPDTFMEQKITYRIWRDTAN--------WLEINPDTGAISTRAELDREDF 553 Query: 545 -----SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580 S Y + A D G P + T + + + DVNDN P+ Sbjct: 554 EHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPI 594 Score = 136 bits (328), Expect = 1e-29 Identities = 122/430 (28%), Positives = 192/430 (44%), Gaps = 26/430 (6%) Query: 391 TDADEDNRLHYEITGGNTR----GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446 ++ D++ ++ Y ITG G F I + G + V +PLD ++ Y L A S Sbjct: 180 SNKDKEGKVFYSITGQGADTPPVGVFIIERETG--WLKVTEPLDRERIATYTLFSHAVSS 237 Query: 447 GGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQI 504 G + D + I +TD N+ P F + SV E A GT+V+ V+ATD+D +N Sbjct: 238 NGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYN 297 Query: 505 TYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL-LDRETMSGYLLTVTARDGGVPSLSD 563 + +S + F IN TG I+ LDRE+ Y L V A D LS Sbjct: 298 AAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLST 357 Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK 623 T I+V D NDN P+F Y + E+ ++ + TDAD Sbjct: 358 TATAVITVTDTNDNPPIFNPTTYKGQVPENE-ANVVITTLKVTDADAPNTPAWEAVYTIL 416 Query: 624 DREEGSFVI--DPAS--GVIRTNKALDRESVATHDLKAVAIDGGTPPQ----SSTVIVHI 675 + + G FV+ +P + G+++T K LD E+ + L VA+ P + +ST V + Sbjct: 417 NDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILH-VAVTNVVPFEVSLTTSTATVTV 475 Query: 676 KIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSF 735 + D+N++P +F +SE+ +G I A +PD + Y I D +N Sbjct: 476 DVLDVNEAP-IFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRI-WRDTANWL 533 Query: 736 SLETRQG--SDKAELVTMVDLDYESPRKKYELVIRA--ASPPLWNDVRVEILVTDVNDNA 791 + G S +AEL D ++ L+I SP + ++++DVNDNA Sbjct: 534 EINPDTGAISTRAEL-DREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNA 592 Query: 792 PVMKDFQIIF 801 P+ + I F Sbjct: 593 PIPEPRTIFF 602 Score = 118 bits (285), Expect = 2e-24 Identities = 139/531 (26%), Positives = 233/531 (43%), Gaps = 44/531 (8%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 VF I+ +G L LDRE++A YT+ A S + + I + + D NDN P Sbjct: 204 VFIIERETGWLKVTEPLDRERIATYTLFSHA---VSSNGNAVEDPMEILITVTDQNDNKP 260 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA---NSAIRYAIIGGNTQM----QFS 201 +F+++ + SV E + ++ ATDAD N+AI Y I+ + ++ F+ Sbjct: 261 EFTQEVFKGSVME--GALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFT 318 Query: 202 IDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260 I+ +G +S+V T LD E +Y LV++A D S T +I + D NDN P F + Sbjct: 319 INRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPT 378 Query: 261 LFQESVSEN-VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDP--RSGW 317 ++ V EN + + ++V DA E YT+ + D +T +P G Sbjct: 379 TYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDD---GGQFVVTTNPVNNDGI 435 Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXX--FMPGQYEVEL 375 + T+ LD E + +Y L V T+ S T + F+P + VE+ Sbjct: 436 LKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEV 495 Query: 376 AEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVAQ--PLDF 431 +ED G + + TA + D + ++ Y I +T I G + T A+ DF Sbjct: 496 SEDFGVGQEITSYTAQEPDTFMEQKITYRI-WRDTANWLEINPDTG-AISTRAELDREDF 553 Query: 432 KQERR--YVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTT 487 + + Y + ATD+G + T + + ++D N+ AP+ E P T E P Sbjct: 554 EHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPE--PRTIFFCERNP---K 608 Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 V++ D+D+ N T ++E+++ A A+ Q+ Q I K+ + Y Sbjct: 609 PQVINIIDADLPPN---TSPFTAELTHGASANWTIQYNDPTQESIILKPKM--ALEVGDY 663 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVF-KQQLYTANIMEDALVG 597 + + D + T +E+SV D V K Q A + A++G Sbjct: 664 KINLKLMDN--QNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQIPAILG 712 Score = 118 bits (284), Expect = 2e-24 Identities = 131/493 (26%), Positives = 213/493 (43%), Gaps = 48/493 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKN---AEVEYTIELVTA 67 I V D ND+ P F + ++ SV EGA GT+V+ + ATD D N A + YTI ++ Sbjct: 250 ITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTI--LSQ 307 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLVKATDQASPV 126 D P+ +++F I+ +G + + LDRE YT++V+A D Sbjct: 308 DPELPD-------------KNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQG-- 352 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 + LS+TAT + + D NDN P F+ TY V E+ + N VI +K TDAD A Sbjct: 353 -EGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEA---NVVITTLKVTDADAPNTPA 408 Query: 187 IR--YAII---GGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTT 241 Y I+ GG + + + G + K LD+E + Y L + + S TT Sbjct: 409 WEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTT 468 Query: 242 Q---LLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTD 298 + +++ DVN+ AP F + VSE+ +G I A + D + ++TY + Sbjct: 469 STATVTVDVLDVNE-APIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIW- 526 Query: 299 KDYTGNVDLPITIDPRSGWVYTSGQLDRE-----TQAKYQLLVTATDGGDPPRSATATXX 353 +D T N + I+P +G + T +LDRE + Y L+ ATD G P AT T Sbjct: 527 RD-TANW---LEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSP--VATGTGT 580 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFS 413 +P + E P + + A + E+T G ++ Sbjct: 581 LLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHG-ASANWT 639 Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENA- 472 I + + +P + Y + + D+ + +++++ D A V A Sbjct: 640 IQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQ 699 Query: 473 PYTASVFEDAPIG 485 P A + A +G Sbjct: 700 PVEAGLQIPAILG 712 Score = 118 bits (283), Expect = 3e-24 Identities = 106/353 (30%), Positives = 168/353 (47%), Gaps = 28/353 (7%) Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583 F+I +TG + + LDRE ++ Y L A ++ D ++ I+V D NDN+P F Q Sbjct: 205 FIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQ 264 Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGL---NGRIHYEL---DPKDREEGSFVIDPASG 637 +++ ++ME AL GTSV +V ATDAD + N I Y + DP+ ++ F I+ +G Sbjct: 265 EVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTG 324 Query: 638 VIR-TNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696 VI LDRES T+ L A D S+T I + D ND+PP+F + Sbjct: 325 VISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQV 384 Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKG--GDDSNSFSLETRQGSDKAELVTMVDL 754 EN I ++ D D PN ++ DD F + T ++ L T L Sbjct: 385 PENE-ANVVITTLKVTDAD-APNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGL 442 Query: 755 DYESPRKKYELVIRAAS-PPL-----WNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCF 808 D+E+ +++Y L + + P + V + V DVN+ AP+ + +D F Sbjct: 443 DFEA-KQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNE-APIFVPPEKRVEVSED-F 499 Query: 809 PVGPFGRVPAYDADVTD-----KLQYRILSGNNANLILLNETTGSMTLSPQLN 856 VG + +Y A D K+ YRI + AN + +N TG+++ +L+ Sbjct: 500 GVGQ--EITSYTAQEPDTFMEQKITYRIWR-DTANWLEINPDTGAISTRAELD 549 Score = 111 bits (266), Expect = 4e-22 Identities = 119/468 (25%), Positives = 196/468 (41%), Gaps = 33/468 (7%) Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDR 326 +E P ++V++++ EG ++ Y++T + I+ +GW+ + LDR Sbjct: 166 NEKGPFPKNLVQIKSNKDKEG---KVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDR 222 Query: 327 ETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386 E A Y L A F ++ + E PGT V+ Sbjct: 223 ERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVM 282 Query: 387 TLTATDADEDNRLH-----YEITGGNTR--GRFSITSQNGRGLITVAQP-LDFKQERRYV 438 +TATDAD+D + Y I + + T G+I+V LD + Y Sbjct: 283 EVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYT 342 Query: 439 LTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFE-DAPIGTTVLVVSATD 495 L V A D G S TA I +TD N+ P+F Y V E +A + T L V+ D Sbjct: 343 LVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDAD 402 Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555 + + Y++ ++ + V + +N G + T K LD E Y+L V + Sbjct: 403 APNTPAWEAVYTILNDDGGQFVVTTNP---VN-NDGILKTAKGLDFEAKQQYILHVAVTN 458 Query: 556 G---GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612 V + T V + V+DVN+ P+F + ED VG ++ A + D + Sbjct: 459 VVPFEVSLTTSTATVTVDVLDVNE-APIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFM 517 Query: 613 NGRIHYELDPKDREEGSFV-IDPASGVIRTNKALDRESV-----ATHDLKAVAIDGGTPP 666 +I Y + R+ +++ I+P +G I T LDRE +T+ +A D G+P Sbjct: 518 EQKITYRIW---RDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPV 574 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDP 714 + T + + + D+ND+ P+ E T + E +P I I A P Sbjct: 575 ATGTGTLLLILSDVNDNAPIPEP--RTIFFCERNPKPQVINIIDADLP 620 >UniRef50_Q96LQ7 Cluster: CDNA FLJ25193 fis, clone JTH00761; n=13; Euteleostomi|Rep: CDNA FLJ25193 fis, clone JTH00761 - Homo sapiens (Human) Length = 493 Score = 153 bits (372), Expect = 5e-35 Identities = 135/415 (32%), Positives = 197/415 (47%), Gaps = 41/415 (9%) Query: 169 PVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIR 228 PV+ +D D G +Y + G F ID +G++ + K+LD E+ Y L+ + Sbjct: 62 PVLIGKLHSDVDRGEGRT-KYLLTGEGAGTVFVIDEATGNIHVTKSLDREEKAQYVLLAQ 120 Query: 229 AQDGGSPSRSNT-TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE- 286 A D S ++ +I ++D+NDN P F + +V E +G S+++V A+DAD+ Sbjct: 121 AVDRASNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDP 180 Query: 287 --GVNAELTYTMTDKDYTGNVDLPI-TIDPRSGWVYTS-GQLDRETQAKYQLLVTATDGG 342 G +A+L YT+ D LP ++DP++G V T+ +DRETQ ++ +++ A D G Sbjct: 181 SYGNSAKLVYTVLD-------GLPFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMG 233 Query: 343 DPPR--SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD-EDNRL 399 S + T F Y+ + E PGT V L A D D DN L Sbjct: 234 GHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNAL 293 Query: 400 H-YEITGGNTRGRFSI-TSQNGR-GLITVAQPLDFKQERRYVLTVSATDS---------G 447 Y I G FSI T GR GL+TV +PLDF+ +R Y V AT++ G Sbjct: 294 MAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRG 353 Query: 448 GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507 D A V++ + DA P F A Y +V E+ GT V +SA D D S Sbjct: 354 PFKDVASVRVAVQDAPE-PPAFTQAAYHLTVPENKAPGTLVGQISAADLD---------S 403 Query: 508 LSSEISNEAVAHHDQQ--FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS 560 +S I + H D + F I P+ G I T LDRE + + LTV A + G S Sbjct: 404 PASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGEDS 458 Score = 138 bits (335), Expect = 2e-30 Identities = 114/374 (30%), Positives = 178/374 (47%), Gaps = 34/374 (9%) Query: 391 TDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR 449 +D D + R Y +TG F I G I V + LD +++ +YVL A D Sbjct: 70 SDVDRGEGRTKYLLTGEGAGTVFVIDEATGN--IHVTKSLDREEKAQYVLLAQAVDRASN 127 Query: 450 ---SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD---VGINAQ 503 + I + D N+ P+F PY A+V E + +GT+V+ V+A D+D G +A+ Sbjct: 128 RPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAK 187 Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITTN-KLLDRETMSGYLLTVTARD--GGVPS 560 + Y++ + F ++PQTG + T +DRET +L+ + A+D G + Sbjct: 188 LVYTVLDGLPF---------FSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHMGG 238 Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE- 619 LS +T V +++ DVNDN P F Q LY +++E A GT V ++ A D D+G N + Y Sbjct: 239 LSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSI 298 Query: 620 LDPKDREEGSFVID--PASGVIRTNKALDRESVATHDLKAVA----IDGG---TPPQSST 670 LD + E S D G++ K LD ES ++ + A ID P Sbjct: 299 LDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDV 358 Query: 671 VIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI-KGG 729 V + ++D + PP F + EN GT +G+I A D D P + + YSI Sbjct: 359 ASVRVAVQDAPE-PPAFTQAAYHLTVPENKAPGTLVGQISAADLD-SPASPIRYSILPHS 416 Query: 730 DDSNSFSLETRQGS 743 D FS++ +G+ Sbjct: 417 DPERCFSIQPEEGT 430 Score = 128 bits (309), Expect = 2e-27 Identities = 111/371 (29%), Positives = 172/371 (46%), Gaps = 18/371 (4%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 VF ID +G + SLDRE+ A+Y +L +A D+AS + L + + + D NDN P Sbjct: 91 VFVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRAS--NRPLEPPSEFIIKVQDINDNPP 148 Query: 149 QFSEKTYTVSVDEDISVTDNPV-IAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSG 207 F Y +V E +V + + + A D G ++ + Y ++ G FS+D +G Sbjct: 149 IFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPF--FSVDPQTG 206 Query: 208 DV-SLVKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQLLINIRDVNDNAPRFYTSLFQE 264 V + + +D E + +VI+A+D G S +T + + + DVNDN P+F SL+Q Sbjct: 207 VVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQF 266 Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 SV E G + R++A D D G NA + Y++ D + + + + R G + L Sbjct: 267 SVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRDGLLTVRKPL 326 Query: 325 DRETQAKYQLLVTATDG-GDPPRSATATXXXXXXXXXXXXX-----XFMPGQYEVELAED 378 D E+Q Y V AT+ DP F Y + + E+ Sbjct: 327 DFESQRSYSFRVEATNTLIDPAYLRRGPFKDVASVRVAVQDAPEPPAFTQAAYHLTVPEN 386 Query: 379 EPPGTPVVTLTATDADED-NRLHYEITGGNTRGR-FSITSQNGRGLITVAQPLDFKQERR 436 + PGT V ++A D D + + Y I + R FSI Q G I A PLD + Sbjct: 387 KAPGTLVGQISAADLDSPASPIRYSILPHSDPERCFSI--QPEEGTIHTAAPLDREARAW 444 Query: 437 YVLTVSATDSG 447 + LTV AT+ G Sbjct: 445 HNLTVLATELG 455 Score = 128 bits (308), Expect = 3e-27 Identities = 116/399 (29%), Positives = 174/399 (43%), Gaps = 32/399 (8%) Query: 283 DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD-G 341 D D G Y +T + G V ID +G ++ + LDRE +A+Y LL A D Sbjct: 71 DVDRG-EGRTKYLLTGEG-AGTV---FVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRA 125 Query: 342 GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN---- 397 + P + F G Y + E GT V+ +TA DAD+ + Sbjct: 126 SNRPLEPPSEFIIKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNS 185 Query: 398 -RLHYEITGGNTRGRFSITSQNGRGLITVAQP-LDFKQERRYVLTVSATDSGGR----SD 451 +L Y + G FS+ Q G ++ A P +D + + +++ + A D GG S Sbjct: 186 AKLVYTVLDGLPF--FSVDPQTG--VVRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSG 241 Query: 452 TAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSE 511 + V + ++D N+ P F + Y SV E A GT V + A D D+G NA + YS+ Sbjct: 242 STTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILDG 301 Query: 512 ISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV-PS------LSDT 564 +EA + + + G +T K LD E+ Y V A + + P+ D Sbjct: 302 EGSEAFSISTD---LQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRGPFKDV 358 Query: 565 TDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKD 624 V ++V D + P F Q Y + E+ GT V Q+ A D D + I Y + P Sbjct: 359 ASVRVAVQDAPE-PPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPAS-PIRYSILPHS 416 Query: 625 REEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGG 663 E F I P G I T LDRE+ A H+L +A + G Sbjct: 417 DPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELG 455 Score = 127 bits (306), Expect = 5e-27 Identities = 94/257 (36%), Positives = 131/257 (50%), Gaps = 15/257 (5%) Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFK 582 FVI+ TG I K LDRE + Y+L A D L ++ I V D+NDN P+F Sbjct: 92 FVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFP 151 Query: 583 QQLYTANIMEDALVGTSVSQVGATDAD---VGLNGRIHYE-LDPKDREEGSFVIDPASGV 638 Y A + E + VGTSV QV A DAD G + ++ Y LD F +DP +GV Sbjct: 152 LGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLP----FFSVDPQTGV 207 Query: 639 IRTN-KALDRESVATH--DLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFY 695 +RT +DRE+ ++A + G S + V + + D+ND+PP F F Sbjct: 208 VRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFS 267 Query: 696 ISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLET-RQGSDKAELVTMVDL 754 + E + GT +G +RA DPD G NA++ YSI G+ S +FS+ T QG D L L Sbjct: 268 VVETAGPGTLVGRLRAQDPDLGDNALMAYSILDGEGSEAFSISTDLQGRD-GLLTVRKPL 326 Query: 755 DYESPRKKYELVIRAAS 771 D+ES R Y + A + Sbjct: 327 DFESQR-SYSFRVEATN 342 Score = 111 bits (266), Expect = 4e-22 Identities = 99/354 (27%), Positives = 171/354 (48%), Gaps = 42/354 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVTA 67 I V D ND+ P+F + Y A+V E ++ GT+V+ + A D D G +A++ YT+ Sbjct: 138 IKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTV----L 193 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRA-SLDREKVARYTVLVKATDQASPV 126 D L F +D ++G + T ++DRE + V+++A D + Sbjct: 194 DGL-----------------PFFSVDPQTGVVRTAIPNMDRETQEEFLVVIQAKDMGGHM 236 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 LS + T+ V + D NDN P+F + Y SV E + ++ +++A D D+G N+ Sbjct: 237 GG-LSGSTTVTVTLSDVNDNPPKFPQSLYQFSVVE--TAGPGTLVGRLRAQDPDLGDNAL 293 Query: 187 IRYAIIGGNTQMQFSIDS-LSGDVSLV---KTLDYEQVRSYRLVIRAQDGG-SPS--RSN 239 + Y+I+ G FSI + L G L+ K LD+E RSY + A + P+ R Sbjct: 294 MAYSILDGEGSEAFSISTDLQGRDGLLTVRKPLDFESQRSYSFRVEATNTLIDPAYLRRG 353 Query: 240 TTQLLINIRDVNDNAPR---FYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 + + ++R +AP F + + +V EN G + ++ A D D + + Y++ Sbjct: 354 PFKDVASVRVAVQDAPEPPAFTQAAYHLTVPENKAPGTLVGQISAADLDSPASP-IRYSI 412 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350 + + +I P G ++T+ LDRE +A + L V AT+ G+ R+ A Sbjct: 413 LPHS---DPERCFSIQPEEGTIHTAAPLDREARAWHNLTVLATELGEDSRAHKA 463 Score = 84.6 bits (200), Expect = 4e-14 Identities = 75/244 (30%), Positives = 121/244 (49%), Gaps = 21/244 (8%) Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT- 664 +D D G GR Y L + FVID A+G I K+LDRE A + L A A+D + Sbjct: 70 SDVDRG-EGRTKYLLTGEGAGT-VFVIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASN 127 Query: 665 -PPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE---GPNA 720 P + + + IK++DIND+PP+F + E S +GT++ ++ AHD D+ G +A Sbjct: 128 RPLEPPSEFI-IKVQDINDNPPIFPLGPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSA 186 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPP-----LW 775 + Y++ G FS++ + G + + M D E+ ++++ +VI+A L Sbjct: 187 KLVYTVLDG--LPFFSVDPQTGVVRTAIPNM---DRET-QEEFLVVIQAKDMGGHMGGLS 240 Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADVTDK--LQYRILS 833 V + ++DVNDN P F+ + P GR+ A D D+ D + Y IL Sbjct: 241 GSTTVTVTLSDVNDNPPKFPQSLYQFSVVETAGPGTLVGRLRAQDPDLGDNALMAYSILD 300 Query: 834 GNNA 837 G + Sbjct: 301 GEGS 304 >UniRef50_P55290 Cluster: Cadherin-13 precursor; n=40; Euteleostomi|Rep: Cadherin-13 precursor - Homo sapiens (Human) Length = 713 Score = 153 bits (372), Expect = 5e-35 Identities = 147/533 (27%), Positives = 230/533 (43%), Gaps = 44/533 (8%) Query: 175 KATDADVGANSAIRYAIIGGNTQMQ--FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDG 232 K D+D S R G + + + F I+ +G VS+ +TLD E + Y+L + D Sbjct: 161 KVVDSDRPERSKFRLTGKGVDQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDV 220 Query: 233 GSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV--NA 290 + L + + D NDN P F + V E P G +++R+ A+DAD+ NA Sbjct: 221 NGKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNA 280 Query: 291 ELTYTMTDKDYTGNVDLPITIDPRSGWVYT---SGQLDRET--QAKYQLLVTATD--GGD 343 L Y + + IDP G + T LDRET KY+L++ A D G D Sbjct: 281 LLRYNIRQQTPDKPSPNMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLD 340 Query: 344 PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN----RL 399 + TAT F +++ + E+ G +V LT D D+ R Sbjct: 341 VGLTGTATATIMIDDKNDHSPKFTKKEFQATV-EEGAVGV-IVNLTVEDKDDPTTGAWRA 398 Query: 400 HYEITGGNTRGRFSI--TSQNGRGLITVAQPLDFKQERRYVLTVSATD--------SGGR 449 Y I GN F I Q G+++V +PLD++ + L + + S G Sbjct: 399 AYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGP 458 Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLS 509 S TA V I + D N PVF P + ED +G+ +L V+ATD D + I YS+ Sbjct: 459 SSTATVHITVLDVNE-GPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVY 517 Query: 510 SEISNEAVAHHDQQFVINPQTGAITTNKLLDRET----MSGYLLTVTARDGGVPSLSDTT 565 + + INP G + T +LDRE+ S Y A D G P + T Sbjct: 518 KDPAG--------WLNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPATGTG 569 Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN-GRIHYELDPKD 624 + I++ DVNDN P + A + +DA SV +GA+D D+ N +E+ + Sbjct: 570 TLLITLEDVNDNAPFIYPTV--AEVCDDA-KNLSVVILGASDKDLHPNTDPFKFEIHKQA 626 Query: 625 REEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 + + I + L + A ++L + D G PP ++ + +++ Sbjct: 627 VPDKVWKISKINNTHALVSLLQNLNKANYNLPIMVTDSGKPPMTNITDLRVQV 679 Score = 125 bits (302), Expect = 2e-26 Identities = 136/478 (28%), Positives = 214/478 (44%), Gaps = 60/478 (12%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD--IGKNAEVEYTIELVTA 67 ++ V+D ND+ P+F Y V EG+ +GTTV+ + A D D NA + Y I T Sbjct: 232 EVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTP 291 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRAS---LDREKV--ARYTVLVKATDQ 122 D +P ++F ID G ++T S LDRE + +Y ++++A D Sbjct: 292 DKPSP---------------NMFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDM 336 Query: 123 ASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVG 182 A + L+ TAT + I D ND+ P+F++K + +V+E VI + D D Sbjct: 337 AG-LDVGLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGAV----GVIVNLTVEDKDDP 391 Query: 183 ANSAIR--YAIIGGNTQMQFSI----DSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG--- 233 A R Y II GN F I + G +S+VK LDYE + L+I+ ++ Sbjct: 392 TTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTLLIKVENEDPLV 451 Query: 234 ---SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290 S S+T + I + DVN+ P FY + E++ +G ++ V A D D + Sbjct: 452 PDVSYGPSSTATVHITVLDVNE-GPVFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQ 510 Query: 291 ELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET----QAKYQLLVTATDGGDPPR 346 + Y++ KD G + I+P +G V T+ LDRE+ + Y L A D G+PP Sbjct: 511 TIRYSVY-KDPAG----WLNINPINGTVDTTAVLDRESPFVDNSVYTALFLAIDSGNPPA 565 Query: 347 SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD---EDNRLHYEI 403 + T T P EV D+ VV L A+D D + +EI Sbjct: 566 TGTGTLLITLEDVNDNAPFIYPTVAEV---CDDAKNLSVVILGASDKDLHPNTDPFKFEI 622 Query: 404 TGGNTRGR-FSITS-QNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINI 459 + + I+ N L+++ Q L+ + Y L + TDSG T + + + Sbjct: 623 HKQAVPDKVWKISKINNTHALVSLLQNLN---KANYNLPIMVTDSGKPPMTNITDLRV 677 Score = 123 bits (296), Expect = 8e-26 Identities = 127/434 (29%), Positives = 196/434 (45%), Gaps = 47/434 (10%) Query: 392 DADEDNRLHYEITGGNT----RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447 D+D R + +TG +G F I G ++V + LD + Y L V TD Sbjct: 164 DSDRPERSKFRLTGKGVDQEPKGIFRINENTGS--VSVTRTLDREVIAVYQLFVETTDVN 221 Query: 448 GRSDTAMV--QINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD--VGINAQ 503 G++ V ++ + D N+ P+F PY V E +P GTTV+ ++A D+D NA Sbjct: 222 GKTLEGPVPLEVIVIDQNDNRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNAL 281 Query: 504 ITYSLSSEISNEAVAHHDQQFVINPQTGAITT---NKLLDRETMSG--YLLTVTARD--G 556 + Y++ + ++ + F I+P+ G I T LLDRET+ Y L + A+D G Sbjct: 282 LRYNIRQQTPDKPSPN---MFYIDPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAG 338 Query: 557 GVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG-- 614 L+ T I + D ND+ P F ++ + A + E A VG V+ + D D G Sbjct: 339 LDVGLTGTATATIMIDDKNDHSPKFTKKEFQATVEEGA-VGVIVN-LTVEDKDDPTTGAW 396 Query: 615 RIHYEL---DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTP--PQ-- 667 R Y + +P E G++ K LD E A H L + ++ P P Sbjct: 397 RAAYTIINGNPGQSFEIHTNPQTNEGMLSVVKPLDYEISAFHTL-LIKVENEDPLVPDVS 455 Query: 668 ---SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHY 724 SST VHI + D+N+ P VF D + E+ +G+ + + A DPD + + Y Sbjct: 456 YGPSSTATVHITVLDVNEGP-VFYPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRY 514 Query: 725 SIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP---RKKYE---LVIRAASPPLWNDV 778 S+ D + ++ G+ + T LD ESP Y L I + +PP Sbjct: 515 SVYK-DPAGWLNINPINGT----VDTTAVLDRESPFVDNSVYTALFLAIDSGNPPATGTG 569 Query: 779 RVEILVTDVNDNAP 792 + I + DVNDNAP Sbjct: 570 TLLITLEDVNDNAP 583 Score = 118 bits (285), Expect = 2e-24 Identities = 123/404 (30%), Positives = 175/404 (43%), Gaps = 39/404 (9%) Query: 311 IDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 I+ +G V + LDRE A YQL V TD F G Sbjct: 190 INENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFREGP 249 Query: 371 YEVELAEDEPPGTPVVTLTATDADE---DNRL-HYEITGGN----TRGRFSITSQNGRGL 422 Y + E P GT V+ +TA DAD+ DN L Y I + F I + G + Sbjct: 250 YIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKG-DI 308 Query: 423 ITVAQPLDFKQER----RYVLTVSATDSGGR----SDTAMVQINITDANNYAPVFENAPY 474 +TV P +E +Y L + A D G + TA I I D N+++P F + Sbjct: 309 VTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKEF 368 Query: 475 TASVFEDAPIGTTV-LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQT--G 531 A+V E+ +G V L V D + Y++ + ++ H NPQT G Sbjct: 369 QATV-EEGAVGVIVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHT-----NPQTNEG 422 Query: 532 AITTNKLLDRETMSGY--LLTVTARDGGVPSLS----DTTDVEISVVDVNDNEPVFKQQL 585 ++ K LD E + + L+ V D VP +S T V I+V+DVN+ PVF Sbjct: 423 MLSVVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVNEG-PVFYPDP 481 Query: 586 YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL 645 ED VG+ + V ATD D + I Y + KD G I+P +G + T L Sbjct: 482 MMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVY-KD-PAGWLNINPINGTVDTTAVL 539 Query: 646 DRESV----ATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPP 685 DRES + + +AID G PP + T + I +ED+ND+ P Sbjct: 540 DRESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAP 583 Score = 116 bits (279), Expect = 9e-24 Identities = 142/518 (27%), Positives = 218/518 (42%), Gaps = 46/518 (8%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +FRI+ +G++ +LDRE +A Y + V+ TD L + V +ID NDN P Sbjct: 187 IFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKT---LEGPVPLEVIVIDQNDNRP 243 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA--NSAIRYAIIGGN----TQMQFSI 202 F E Y V E S T V+ ++ A DAD A N+ +RY I + F I Sbjct: 244 IFREGPYIGHVMEG-SPTGTTVM-RMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYI 301 Query: 203 DSLSGDVSLVKT---LDYEQVRS--YRLVIRAQD--GGSPSRSNTTQLLINIRDVNDNAP 255 D GD+ V + LD E + + Y L+I AQD G + T I I D ND++P Sbjct: 302 DPEKGDIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSP 361 Query: 256 RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA--ELTYTMTDKDYTGNVDLPITIDP 313 +F FQ +V E +G IV + D D+ YT+ + + + ++ Sbjct: 362 KFTKKEFQATVEEGA-VGV-IVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQT 419 Query: 314 RSGWVYTSGQLDRETQAKYQLLVTATDGGDP-------PRSATATXXXXXXXXXXXXXXF 366 G + LD E A + LL+ + DP S+TAT F Sbjct: 420 NEGMLSVVKPLDYEISAFHTLLI-KVENEDPLVPDVSYGPSSTAT-VHITVLDVNEGPVF 477 Query: 367 MPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLIT 424 P V ED G+ ++T+ ATD D + + Y + + G +I NG T Sbjct: 478 YPDPMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVY-KDPAGWLNINPINGTVDTT 536 Query: 425 VA--QPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480 + F Y A DSG + T + I + D N+ AP P A V + Sbjct: 537 AVLDRESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFI--YPTVAEVCD 594 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLD 540 DA +V+++ A+D D+ N T EI +AV D+ + I+ LL Sbjct: 595 DAK-NLSVVILGASDKDLHPN---TDPFKFEIHKQAVP--DKVWKISKINNTHALVSLLQ 648 Query: 541 RETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNE 578 + Y L + D G P +++ TD+ + V +++ Sbjct: 649 NLNKANYNLPIMVTDSGKPPMTNITDLRVQVCSCRNSK 686 Score = 94.7 bits (225), Expect = 3e-17 Identities = 97/361 (26%), Positives = 152/361 (42%), Gaps = 28/361 (7%) Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583 F IN TG+++ + LDRE ++ Y L V D +L +E+ V+D NDN P+F++ Sbjct: 188 FRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQNDNRPIFRE 247 Query: 584 QLYTANIMEDALVGTSVSQVGATDAD--VGLNGRIHYEL---DPKDREEGSFVIDPASGV 638 Y ++ME + GT+V ++ A DAD N + Y + P F IDP G Sbjct: 248 GPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGD 307 Query: 639 IRT---NKALDRESVAT--HDLKAVAID--GGTPPQSSTVIVHIKIEDINDSPPVFESDC 691 I T LDRE++ ++L A D G + T I I+D ND P F Sbjct: 308 IVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKE 367 Query: 692 LTFYISENSPIGTTIGEIRAHDPDEGPNAV--VHYSIKGGDDSNSFSLETRQGSDKAELV 749 + E + +G + + D D+ Y+I G+ SF + T +++ L Sbjct: 368 FQATVEEGA-VGVIV-NLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLS 425 Query: 750 TMVDLDYESPRKKYELVIRAASPPLWNDV--------RVEILVTDVNDNAPVMKDFQIIF 801 + LDYE L+ PL DV V I V DVN+ PV ++ Sbjct: 426 VVKPLDYEISAFHTLLIKVENEDPLVPDVSYGPSSTATVHITVLDVNE-GPVFYPDPMMV 484 Query: 802 NNYKDCFPVGPFGRVPAYDADVT--DKLQYRILSGNNANLILLNETTGSMTLSPQLNTNV 859 +D V A D D ++Y + + A + +N G++ + L+ Sbjct: 485 TRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYK-DPAGWLNINPINGTVDTTAVLDRES 543 Query: 860 P 860 P Sbjct: 544 P 544 Score = 68.1 bits (159), Expect = 3e-09 Identities = 55/190 (28%), Positives = 89/190 (46%), Gaps = 16/190 (8%) Query: 624 DRE-EGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDIND 682 D+E +G F I+ +G + + LDRE +A + L D V + + + D ND Sbjct: 181 DQEPKGIFRINENTGSVSVTRTLDREVIAVYQLFVETTDVNGKTLEGPVPLEVIVIDQND 240 Query: 683 SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE--GPNAVVHYSIK----GGDDSNSFS 736 + P+F ++ E SP GTT+ + A D D+ NA++ Y+I+ N F Sbjct: 241 NRPIFREGPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFY 300 Query: 737 LETRQGSDKAELVTMVDLDYES-PRKKYELVIRAASPP-----LWNDVRVEILVTDVNDN 790 ++ +G D +V+ LD E+ KYEL+I A L I++ D ND+ Sbjct: 301 IDPEKG-DIVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDH 359 Query: 791 AP--VMKDFQ 798 +P K+FQ Sbjct: 360 SPKFTKKEFQ 369 >UniRef50_Q4SS36 Cluster: Chromosome 11 SCAF14479, whole genome shotgun sequence; n=2; Euteleostomi|Rep: Chromosome 11 SCAF14479, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 908 Score = 153 bits (371), Expect = 7e-35 Identities = 154/525 (29%), Positives = 234/525 (44%), Gaps = 51/525 (9%) Query: 178 DADVGANSAIRYAIIGGNTQMQ----FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGG 233 D DVG IRY+I G ++ID +SG++ + + LD E S+ L A D Sbjct: 223 DKDVG----IRYSITGAGADQPPSGIYNIDPISGNMFVTQPLDREDRASFHLRAHAVDMN 278 Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEG--VNAE 291 N +L I + D+NDN P F ++ SV+E G S+++V A D+D+ N Sbjct: 279 GNQVENPIELYIYVIDMNDNRPEFQNQVYNGSVAEGSKPGSSVMQVTATDSDDSTTANGM 338 Query: 292 LTYTMTDKDYTGNVDLPITIDPRSGWVYT-SGQLDRETQAKYQLLVTATD--GG-DPPRS 347 + Y + + + TI+ +G + T S LDRE ++Y ++V ATD G + S Sbjct: 339 VRYRILSQTPHNPIPNMFTINSETGDIVTVSAGLDREKVSQYTIIVQATDMEGNLNFGLS 398 Query: 348 ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH----YEI 403 TAT + E+ E++ V LT D D+ + + Y I Sbjct: 399 NTATALISITDINDNPPELTVRTFSGEVPENK-VNVVVTNLTVVDRDQPHSPNWNAVYRI 457 Query: 404 TGGNTRGRFSITSQ--NGRGLITVAQPLDFKQERRYVLTVSATD-----SGGRS---DTA 453 GG+ G F+I + G++TV +P+DF+ R + LTV ++ SG +S TA Sbjct: 458 VGGDPTGHFTIHTNPITNEGMLTVIKPVDFEMNRAFGLTVVVSNQAHLASGIQSSLQSTA 517 Query: 454 MVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEIS 513 V I++ D N PVF P E P GTT+ V +A D D I+ + YS S+ + Sbjct: 518 GVTISVQDVNE-PPVFPVNPKMIRFEEGVPAGTTLTVFAAQDPDRFIHQIVRYSKLSDPA 576 Query: 514 NEAVAHHDQQFVINPQTGAITTNKLLDRETM----SGYLLTVTARD---GGVPSLSDTTD 566 N IN G ITT LLDRE+M + Y T A D G P S T Sbjct: 577 N--------WLKINRTNGQITTMALLDRESMFVKNNVYEATFLAFDNGKSGSPPASGTGT 628 Query: 567 VEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLN-GRIHYELDPKDR 625 ++I ++DVNDN P + A + + + ++ + A D D N G +EL Sbjct: 629 LQIYLIDVNDNAPELIPR--EAQLCDRPRPNSRIN-ITAADGDADPNVGPFVFELPSFPA 685 Query: 626 E-EGSFVIDPASG-VIRTNKALDRESVATHDLKAVAIDGGTPPQS 668 ++ I +G + L +D+ + D G PP S Sbjct: 686 SVRRNWTISRLNGDYAQLKLRLSYLEAGVYDIPVIVSDSGNPPLS 730 Score = 137 bits (331), Expect = 5e-30 Identities = 132/435 (30%), Positives = 195/435 (44%), Gaps = 46/435 (10%) Query: 391 TDADEDNRLHYEITGGNT----RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446 +D D+D + Y ITG G ++I +G +T QPLD + + L A D Sbjct: 220 SDQDKDVGIRYSITGAGADQPPSGIYNIDPISGNMFVT--QPLDREDRASFHLRAHAVDM 277 Query: 447 GGRSDTAMVQ--INITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSD--VGINA 502 G ++ I + D N+ P F+N Y SV E + G++V+ V+ATDSD N Sbjct: 278 NGNQVENPIELYIYVIDMNDNRPEFQNQVYNGSVAEGSKPGSSVMQVTATDSDDSTTANG 337 Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL-LDRETMSGYLLTVTARD--GGVP 559 + Y + S+ + + + F IN +TG I T LDRE +S Y + V A D G + Sbjct: 338 MVRYRILSQTPHNPIPN---MFTINSETGDIVTVSAGLDREKVSQYTIIVQATDMEGNLN 394 Query: 560 -SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV--GLNGRI 616 LS+T IS+ D+NDN P + ++ + E+ V V+ + D D N Sbjct: 395 FGLSNTATALISITDINDNPPELTVRTFSGEVPENK-VNVVVTNLTVVDRDQPHSPNWNA 453 Query: 617 HYELDPKDREEGSFVI--DPAS--GVIRTNKALDRESVATHDLKAVAID------GGTPP 666 Y + D G F I +P + G++ K +D E L V + G Sbjct: 454 VYRIVGGD-PTGHFTIHTNPITNEGMLTVIKPVDFEMNRAFGLTVVVSNQAHLASGIQSS 512 Query: 667 QSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSI 726 ST V I ++D+N+ PPVF + E P GTT+ A DPD + +V YS Sbjct: 513 LQSTAGVTISVQDVNE-PPVFPVNPKMIRFEEGVPAGTTLTVFAAQDPDRFIHQIVRYS- 570 Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKK---YELVI------RAASPPLWND 777 K D +N + G ++ TM LD ES K YE ++ SPP Sbjct: 571 KLSDPANWLKINRTNG----QITTMALLDRESMFVKNNVYEATFLAFDNGKSGSPPASGT 626 Query: 778 VRVEILVTDVNDNAP 792 ++I + DVNDNAP Sbjct: 627 GTLQIYLIDVNDNAP 641 Score = 132 bits (319), Expect = 1e-28 Identities = 125/466 (26%), Positives = 209/466 (44%), Gaps = 51/466 (10%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 I I V+D ND+ P F+ Q Y SV EG+ G++V+ + ATD D A +++ Sbjct: 286 IELYIYVIDMNDNRPEFQNQVYNGSVAEGSKPGSSVMQVTATDSDDSTTANGMVRYRILS 345 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLT-RASLDREKVARYTVLVKATDQASP 125 NP + ++F I+ +G ++T A LDREKV++YT++V+ATD Sbjct: 346 QTPHNP-------------IPNMFTINSETGDIVTVSAGLDREKVSQYTIIVQATDMEGN 392 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADV--GA 183 ++ LS+TAT ++I D NDN P+ + +T++ V E+ N V+ + D D Sbjct: 393 LNFGLSNTATALISITDINDNPPELTVRTFSGEVPEN---KVNVVVTNLTVVDRDQPHSP 449 Query: 184 NSAIRYAIIGGNTQMQFSID----SLSGDVSLVKTLDYEQVRSYRLVI------RAQDGG 233 N Y I+GG+ F+I + G ++++K +D+E R++ L + G Sbjct: 450 NWNAVYRIVGGDPTGHFTIHTNPITNEGMLTVIKPVDFEMNRAFGLTVVVSNQAHLASGI 509 Query: 234 SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELT 293 S +T + I+++DVN+ P F + E VP G ++ A D D ++ + Sbjct: 510 QSSLQSTAGVTISVQDVNE-PPVFPVNPKMIRFEEGVPAGTTLTVFAAQDPDRFIHQIVR 568 Query: 294 YTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET----QAKYQLLVTATD---GGDPPR 346 Y+ + I+ +G + T LDRE+ Y+ A D G PP Sbjct: 569 YSKLSDPANW-----LKINRTNGQITTMALLDRESMFVKNNVYEATFLAFDNGKSGSPPA 623 Query: 347 SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLH---YEI 403 S T T +P E +L D P + +TA D D D + +E+ Sbjct: 624 SGTGTLQIYLIDVNDNAPELIP--REAQLC-DRPRPNSRINITAADGDADPNVGPFVFEL 680 Query: 404 TG--GNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSG 447 + R ++I+ NG + L + + Y + V +DSG Sbjct: 681 PSFPASVRRNWTISRLNG-DYAQLKLRLSYLEAGVYDIPVIVSDSG 725 Score = 107 bits (256), Expect = 6e-21 Identities = 104/385 (27%), Positives = 179/385 (46%), Gaps = 33/385 (8%) Query: 488 VLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGY 547 V + S D DVGI IT + + + + + I+P +G + + LDRE + + Sbjct: 216 VRIRSDQDKDVGIRYSITGAGADQPPSGI-------YNIDPISGNMFVTQPLDREDRASF 268 Query: 548 LLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATD 607 L A D + + ++ I V+D+NDN P F+ Q+Y ++ E + G+SV QV ATD Sbjct: 269 HLRAHAVDMNGNQVENPIELYIYVIDMNDNRPEFQNQVYNGSVAEGSKPGSSVMQVTATD 328 Query: 608 AD--VGLNGRIHYEL---DPKDREEGSFVIDPASG-VIRTNKALDRESVATHDL--KAVA 659 +D NG + Y + P + F I+ +G ++ + LDRE V+ + + +A Sbjct: 329 SDDSTTANGMVRYRILSQTPHNPIPNMFTINSETGDIVTVSAGLDREKVSQYTIIVQATD 388 Query: 660 IDGGTP-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDE-- 716 ++G S+T I I DIND+PP + + EN + + + D D+ Sbjct: 389 MEGNLNFGLSNTATALISITDINDNPPELTVRTFSGEVPENK-VNVVVTNLTVVDRDQPH 447 Query: 717 GPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWN 776 PN Y I GGD + F++ T +++ L + +D+E R V+ + L + Sbjct: 448 SPNWNAVYRIVGGDPTGHFTIHTNPITNEGMLTVIKPVDFEMNRAFGLTVVVSNQAHLAS 507 Query: 777 DVR--------VEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRV-PAYDAD--VTD 825 ++ V I V DVN+ + ++I +++ P G V A D D + Sbjct: 508 GIQSSLQSTAGVTISVQDVNEPPVFPVNPKMI--RFEEGVPAGTTLTVFAAQDPDRFIHQ 565 Query: 826 KLQYRILSGNNANLILLNETTGSMT 850 ++Y LS + AN + +N T G +T Sbjct: 566 IVRYSKLS-DPANWLKINRTNGQIT 589 Score = 99.5 bits (237), Expect = 1e-18 Identities = 115/442 (26%), Positives = 179/442 (40%), Gaps = 42/442 (9%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 ++ ID SG + LDRE A + + A D +++ + +++ +ID NDN P Sbjct: 244 IYNIDPISGNMFVTQPLDREDRASFHLRAHAVDMNG---NQVENPIELYIYVIDMNDNRP 300 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDAD--VGANSAIRYAIIGGNTQ----MQFSI 202 +F + Y SV E + + ++ ATD+D AN +RY I+ F+I Sbjct: 301 EFQNQVYNGSVAEGSKPGSS--VMQVTATDSDDSTTANGMVRYRILSQTPHNPIPNMFTI 358 Query: 203 DSLSGDVSLVKT-LDYEQVRSYRLVIRAQD--GG-SPSRSNTTQLLINIRDVNDNAPRFY 258 +S +GD+ V LD E+V Y ++++A D G + SNT LI+I D+NDN P Sbjct: 359 NSETGDIVTVSAGLDREKVSQYTIIVQATDMEGNLNFGLSNTATALISITDINDNPPELT 418 Query: 259 TSLFQESVSEN-VPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGW 317 F V EN V + + + V D N Y + D TG+ + G Sbjct: 419 VRTFSGEVPENKVNVVVTNLTVVDRDQPHSPNWNAVYRIVGGDPTGHFTIHTNPITNEGM 478 Query: 318 VYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV---- 373 + +D E + L V ++ ++ P + V Sbjct: 479 LTVIKPVDFEMNRAFGLTVVVSNQAHLASGIQSSLQSTAGVTISVQDVNEPPVFPVNPKM 538 Query: 374 -ELAEDEPPGTPVVTLTATDADEDNRLHYEITG----GNTRGRFSITSQNGRGLITVAQP 428 E P GT TLT A + +R ++I + I NG+ IT Sbjct: 539 IRFEEGVPAGT---TLTVFAAQDPDRFIHQIVRYSKLSDPANWLKINRTNGQ--ITTMAL 593 Query: 429 LD----FKQERRYVLTVSATDSG-----GRSDTAMVQINITDANNYAPVFENAPYTASVF 479 LD F + Y T A D+G S T +QI + D N+ AP E P A + Sbjct: 594 LDRESMFVKNNVYEATFLAFDNGKSGSPPASGTGTLQIYLIDVNDNAP--ELIPREAQLC 651 Query: 480 EDAPIGTTVLVVSATDSDVGIN 501 D P + + ++A D D N Sbjct: 652 -DRPRPNSRINITAADGDADPN 672 >UniRef50_A7RRZ9 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 550 Score = 151 bits (367), Expect = 2e-34 Identities = 137/507 (27%), Positives = 223/507 (43%), Gaps = 44/507 (8%) Query: 89 VFRIDGRSGALLTRASLDREKVAR------YTVLVKATDQASPVSDRLSSTATIHVNIID 142 +F I+ +G L T+ L+REK+ + + +K T VS +T V ++D Sbjct: 64 IFEINAATGVLRTKILLNREKLPPSAQGDIFQIQIKVTTDTGGVS----ATIPTEVRVLD 119 Query: 143 DNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSI 202 ND+ P+F + + + E S + +A DAD+G NS Y I+ GN FS+ Sbjct: 120 INDHSPKFPQDFEELQISE--SAPERSKFPLQRALDADIGNNSIQEYRIVRGNEDGLFSL 177 Query: 203 D--SLSGDVSLV-----KTLDYEQVRSYRLVIRAQDGGSP-SRSNTTQLLINIRDVNDNA 254 S D+ V K LD E Y+LVI A DGG P RS ++ I I D ND++ Sbjct: 178 SLKRFSPDMIYVYLVNTKRLDRETRDFYQLVIVAVDGGFPLPRSGRKEVNITILDSNDHS 237 Query: 255 PRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPR 314 P F + SV EN P G ++RV A D D G N E+ + + + G +D Sbjct: 238 PEFSKDFYTASVPENAPNGTYLLRVTAIDQDIGKNGEIMFYLDESPERG----LFRMDEY 293 Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGGD---PPRS-ATATXXXXXXXXXXXXXXFMPGQ 370 +G ++T+ LD E +++Y+L V A D G P R+ T +P Sbjct: 294 TGEIWTNAVLDYEVKSEYRLTVVAQDQGPDSIPVRAQVTIKDKNDNAPTIQVKLLQVPNA 353 Query: 371 YEVELA-EDEPPGTPVVTLTATDADEDNRLH--YEITGGNTRGRFSITS-QNGRGLITVA 426 L ED G+ V + D D ++ ++T + + F++ N + V Sbjct: 354 ARPGLVPEDITTGSNVAIVEVRDRDSSLTVNSVVDVTLLHHKHDFALRRIFNTFYNLEVQ 413 Query: 427 QPLDFKQERRYVLTVSATDSG--GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 +PL+ ++ Y + A D G + ++I D N + P + ++ ++ Sbjct: 414 RPLNLTRQSIYKIDFIARDRGVPTLETNNSLTLHIEDKNRHTPTYPTPSRDITIIDNTQP 473 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 G V+ + ATD D G+N +I YSL + D+ F+++ G + + + Sbjct: 474 GDEVVTIRATDPDSGLNGKIQYSL-------IAGNDDKTFILDKDRGELV---VFNYMFQ 523 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISV 571 S Y+LT+ A D G P + I V Sbjct: 524 SSYVLTIKASDSGNPPSESLVRIRIRV 550 Score = 151 bits (365), Expect = 4e-34 Identities = 124/463 (26%), Positives = 198/463 (42%), Gaps = 31/463 (6%) Query: 231 DGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNA 290 D G S + T+ + + D+ND++P+F + +SE+ P +A DAD G N+ Sbjct: 103 DTGGVSATIPTE--VRVLDINDHSPKFPQDFEELQISESAPERSKFPLQRALDADIGNNS 160 Query: 291 ELTYTMTDKDYTGNVDLPIT-IDPRSGWVY--TSGQLDRETQAKYQLLVTATDGGDP-PR 346 Y + + G L + P +VY + +LDRET+ YQL++ A DGG P PR Sbjct: 161 IQEYRIVRGNEDGLFSLSLKRFSPDMIYVYLVNTKRLDRETRDFYQLVIVAVDGGFPLPR 220 Query: 347 SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEIT 404 S F Y + E+ P GT ++ +TA D D ++ + + + Sbjct: 221 SGRKEVNITILDSNDHSPEFSKDFYTASVPENAPNGTYLLRVTAIDQDIGKNGEIMFYLD 280 Query: 405 GGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANN 464 RG F + G I LD++ + Y LTV A D G S Q+ I D N+ Sbjct: 281 ESPERGLFRMDEYTGE--IWTNAVLDYEVKSEYRLTVVAQDQGPDSIPVRAQVTIKDKND 338 Query: 465 YAPVFE-------NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAV 517 AP + NA V ED G+ V +V D D + + + + + Sbjct: 339 NAPTIQVKLLQVPNAARPGLVPEDITTGSNVAIVEVRDRDSSLTV-------NSVVDVTL 391 Query: 518 AHHDQQFVINPQTGA---ITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 HH F + + + L+ S Y + ARD GVP+L + + + D Sbjct: 392 LHHKHDFALRRIFNTFYNLEVQRPLNLTRQSIYKIDFIARDRGVPTLETNNSLTLHIEDK 451 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634 N + P + I+++ G V + ATD D GLNG+I Y L ++ +F++D Sbjct: 452 NRHTPTYPTPSRDITIIDNTQPGDEVVTIRATDPDSGLNGKIQYSL-IAGNDDKTFILDK 510 Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 G + + + S + L A D G PP S V + I++ Sbjct: 511 DRGELVVFNYMFQSS---YVLTIKASDSGNPPSESLVRIRIRV 550 Score = 141 bits (342), Expect = 2e-31 Identities = 118/462 (25%), Positives = 192/462 (41%), Gaps = 33/462 (7%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVT 66 I ++ VLD NDHSP F E + E A + +A D DIG N+ EY I Sbjct: 111 IPTEVRVLDINDHSPKFPQDFEELQISESAPERSKFPLQRALDADIGNNSIQEYRIVRGN 170 Query: 67 ADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPV 126 D L D+ + L+ LDRE Y +++ A D P+ Sbjct: 171 EDGL-------FSLSLKRFSPDMIYV-----YLVNTKRLDRETRDFYQLVIVAVDGGFPL 218 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 S +++ I+D ND+ P+FS+ YT SV E+ + + ++ A D D+G N Sbjct: 219 PR--SGRKEVNITILDSNDHSPEFSKDFYTASVPEN--APNGTYLLRVTAIDQDIGKNGE 274 Query: 187 IRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLIN 246 I + + + F +D +G++ LDYE YRL + AQD G S Q + Sbjct: 275 IMFYLDESPERGLFRMDEYTGEIWTNAVLDYEVKSEYRLTVVAQDQGPDSIPVRAQ--VT 332 Query: 247 IRDVNDNAPRFYTSLFQES-------VSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 I+D NDNAP L Q V E++ G ++ V+ D D + +T Sbjct: 333 IKDKNDNAPTIQVKLLQVPNAARPGLVPEDITTGSNVAIVEVRDRDSSLTVNSVVDVTLL 392 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXX 359 + + L + + L+ Q+ Y++ A D G P + Sbjct: 393 HHKHDFALRRIFNTFYN-LEVQRPLNLTRQSIYKIDFIARDRGVPTLETNNSLTLHIEDK 451 Query: 360 XXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQ 417 + ++ + ++ PG VVT+ ATD D + ++ Y + GN F + Sbjct: 452 NRHTPTYPTPSRDITIIDNTQPGDEVVTIRATDPDSGLNGKIQYSLIAGNDDKTFILDKD 511 Query: 418 NGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINI 459 G ++ ++ + YVLT+ A+DSG ++V+I I Sbjct: 512 RGELVV-----FNYMFQSSYVLTIKASDSGNPPSESLVRIRI 548 Score = 140 bits (340), Expect = 4e-31 Identities = 138/474 (29%), Positives = 208/474 (43%), Gaps = 42/474 (8%) Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392 Q+ VT GG SAT F E++++E P + A D Sbjct: 97 QIKVTTDTGGV---SATIPTEVRVLDINDHSPKFPQDFEELQISESAPERSKFPLQRALD 153 Query: 393 ADEDNRL--HYEITGGNTRGRFSITSQN-GRGLITV----AQPLDFKQERRYVLTVSATD 445 AD N Y I GN G FS++ + +I V + LD + Y L + A D Sbjct: 154 ADIGNNSIQEYRIVRGNEDGLFSLSLKRFSPDMIYVYLVNTKRLDRETRDFYQLVIVAVD 213 Query: 446 SG---GRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINA 502 G RS V I I D+N+++P F YTASV E+AP GT +L V+A D D+G N Sbjct: 214 GGFPLPRSGRKEVNITILDSNDHSPEFSKDFYTASVPENAPNGTYLLRVTAIDQDIGKNG 273 Query: 503 QITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLS 562 +I + L F ++ TG I TN +LD E S Y LTV A+D G S+ Sbjct: 274 EIMFYLDESPERGL-------FRMDEYTGEIWTNAVLDYEVKSEYRLTVVAQDQGPDSI- 325 Query: 563 DTTDVEISVVDVNDNEPVFKQQLYTAN-------IMEDALVGTSVSQVGATDADVGL--N 613 ++++ D NDN P + +L + ED G++V+ V D D L N Sbjct: 326 -PVRAQVTIKDKNDNAPTIQVKLLQVPNAARPGLVPEDITTGSNVAIVEVRDRDSSLTVN 384 Query: 614 GRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIV 673 + L + I + + L+ + + + +A D G P + + Sbjct: 385 SVVDVTLLHHKHDFALRRIFNTFYNLEVQRPLNLTRQSIYKIDFIARDRGVPTLETNNSL 444 Query: 674 HIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSN 733 + IED N P + + I +N+ G + IRA DPD G N + YS+ G+D Sbjct: 445 TLHIEDKNRHTPTYPTPSRDITIIDNTQPGDEVVTIRATDPDSGLNGKIQYSLIAGNDDK 504 Query: 734 SFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAA---SPPLWNDVRVEILV 784 +F L+ D+ ELV + + ++S Y L I+A+ +PP + VR+ I V Sbjct: 505 TFILD----KDRGELV-VFNYMFQS---SYVLTIKASDSGNPPSESLVRIRIRV 550 Score = 136 bits (329), Expect = 8e-30 Identities = 134/503 (26%), Positives = 225/503 (44%), Gaps = 33/503 (6%) Query: 374 ELAEDEPPGTPVVTLTATDADEDNRL-----HYEITGGNTRGRFSITSQNG--RGLITVA 426 ++ E++ PG V ++ TD + RL Y+I G G F I + G R I + Sbjct: 23 QVKEEQDPGALVGDVSQTDIPKRLRLSFGKIRYQIQGP-ADGIFEINAATGVLRTKILLN 81 Query: 427 Q---PLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAP 483 + P + + + TD+GG S T ++ + D N+++P F + E AP Sbjct: 82 REKLPPSAQGDIFQIQIKVTTDTGGVSATIPTEVRVLDINDHSPKFPQDFEELQISESAP 141 Query: 484 IGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 + + A D+D+G N+ Y + + + ++F + + K LDRET Sbjct: 142 ERSKFPLQRALDADIGNNSIQEYRIVRGNEDGLFSLSLKRFSPDMIYVYLVNTKRLDRET 201 Query: 544 MSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQ 602 Y L + A DGG P S +V I+++D ND+ P F + YTA++ E+A GT + + Sbjct: 202 RDFYQLVIVAVDGGFPLPRSGRKEVNITILDSNDHSPEFSKDFYTASVPENAPNGTYLLR 261 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDG 662 V A D D+G NG I + LD + E G F +D +G I TN LD E + + L VA D Sbjct: 262 VTAIDQDIGKNGEIMFYLD-ESPERGLFRMDEYTGEIWTNAVLDYEVKSEYRLTVVAQDQ 320 Query: 663 GTPPQSSTVIVHIKIEDINDSPPVFESDCLTF-------YISENSPIGTTIG--EIRAHD 713 G P S V + I+D ND+ P + L + E+ G+ + E+R D Sbjct: 321 G--PDSIPVRAQVTIKDKNDNAPTIQVKLLQVPNAARPGLVPEDITTGSNVAIVEVRDRD 378 Query: 714 PDEGPNAVVHYSIKGGDDSNSFSLETRQGSD-KAELVTMVDLDYESPRKKYELVIRAASP 772 N+VV ++ + F+L + E+ ++L +S K + P Sbjct: 379 SSLTVNSVVDVTLL--HHKHDFALRRIFNTFYNLEVQRPLNLTRQSIYKIDFIARDRGVP 436 Query: 773 PLWNDVRVEILVTDVNDNAPVM----KDFQIIFNNYKDCFPVGPFGRVPAYDADVTDKLQ 828 L + + + + D N + P +D II N V P D+ + K+Q Sbjct: 437 TLETNNSLTLHIEDKNRHTPTYPTPSRDITIIDNTQPGDEVVTIRATDP--DSGLNGKIQ 494 Query: 829 YRILSGNNANLILLNETTGSMTL 851 Y +++GN+ +L++ G + + Sbjct: 495 YSLIAGNDDKTFILDKDRGELVV 517 >UniRef50_UPI0000660AA1 Cluster: Cadherin-7 precursor.; n=1; Takifugu rubripes|Rep: Cadherin-7 precursor. - Takifugu rubripes Length = 784 Score = 151 bits (365), Expect = 4e-34 Identities = 170/583 (29%), Positives = 261/583 (44%), Gaps = 79/583 (13%) Query: 161 EDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV 220 E+ + D + K+ + D D G + +RY + G FSID +GD+ + LD EQ Sbjct: 17 EEFTGNDPLYVGKLHS-DVDKG-DGQVRYVLTGEGAASIFSIDESTGDIHATRRLDREQQ 74 Query: 221 RSYRLVIRAQDGGSPSRSNT-TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRV 279 Y L +A++ + +Q +I ++DVNDN P+F + V+E P+G S+V V Sbjct: 75 AYYTLRAQARNRDTNRLVEPESQFIIKVQDVNDNEPKFLDGPYTARVAERSPVGTSVVTV 134 Query: 280 QAYDADE---GVNAELTYTMTD-KDYTGNVDLPITIDPRSGWVYTS-GQLDRETQAKYQL 334 A DAD+ G +A L Y++ + Y +++P++G V T+ LDRE + + L Sbjct: 135 VATDADDPTYGNSARLMYSILQGQPY-------FSVEPKTGVVRTALPDLDREVRDSHLL 187 Query: 335 LVTATD--GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392 +V A D G S + + F Y+ + E E T V + A D Sbjct: 188 VVQAKDMIGQIGGLSGSTSVTVILTDVNDNPPHFPRRSYQFSVRESELVSTVVAKIRAVD 247 Query: 393 ADE--DNRLHYEITGGNTRGRFSIT--SQNGRGLITVAQPLDFKQERRYVLTVSATD--- 445 DE + L Y I G+ G FSIT S GLIT+ + LDF+ + Y+L V A++ Sbjct: 248 PDEGPNAELDYRILDGDGLGIFSITTDSHTQEGLITLHKNLDFETKSSYMLRVEASNLYV 307 Query: 446 ------SGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV-----SAT 494 SG SD A V++ + + + PVF ++ V E A +GT V V AT Sbjct: 308 DARFLSSGPFSDVATVRLLVQNVDE-PPVFHSSVSWMMVSEAAAVGTEVGSVLARDPDAT 366 Query: 495 DSDVGINAQITYSL-----------SSEISNEAVAHHDQQFVINPQTGAITTNKLLDRET 543 +S + I+A L S S + ++ ++ F I+ TG ITT + LDRET Sbjct: 367 NSPIRISADAAPPLTRCWCPNSLGSSCRYSIDRQSNLERYFHIDSGTGVITTAQPLDRET 426 Query: 544 MSGYLLTVTARDGG-----------------------VPSLSDTTDVEISVVDVNDNEPV 580 ++ + +TV A + PSL+ V ISV DVNDN P Sbjct: 427 VAVHNITVVATERQHFLAVHSCLFSAWVTSCLVLMPVDPSLTGKAVVLISVTDVNDNPPS 486 Query: 581 FKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEG-SFVI-----DP 634 Y + E++ G V + A D D G+ H+ + + SF + + Sbjct: 487 LAID-YDTFVCENSEPGQIVQTLSAVDRDEPEEGQ-HFLFSLSEAGQNLSFTLRDNKDNT 544 Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 AS + R L R+ + H L V D PP SST + I + Sbjct: 545 ASILTRPGGFLQRDQL-LHLLPVVISDSSRPPLSSTNTLSITV 586 Score = 148 bits (359), Expect = 2e-33 Identities = 110/343 (32%), Positives = 169/343 (49%), Gaps = 28/343 (8%) Query: 391 TDADE-DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR 449 +D D+ D ++ Y +TG FSI G I + LD +Q+ Y L A + Sbjct: 32 SDVDKGDGQVRYVLTGEGAASIFSIDESTGD--IHATRRLDREQQAYYTLRAQARNRDTN 89 Query: 450 ---SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITY 506 + I + D N+ P F + PYTA V E +P+GT+V+ V ATD+D TY Sbjct: 90 RLVEPESQFIIKVQDVNDNEPKFLDGPYTARVAERSPVGTSVVTVVATDAD-----DPTY 144 Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAI-TTNKLLDRETMSGYLLTVTARD--GGVPSLSD 563 S+ + ++ F + P+TG + T LDRE +LL V A+D G + LS Sbjct: 145 GNSARLM-YSILQGQPYFSVEPKTGVVRTALPDLDREVRDSHLLVVQAKDMIGQIGGLSG 203 Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPK 623 +T V + + DVNDN P F ++ Y ++ E LV T V+++ A D D G N + Y + Sbjct: 204 STSVTVILTDVNDNPPHFPRRSYQFSVRESELVSTVVAKIRAVDPDEGPNAELDYRILDG 263 Query: 624 DREEGSFVIDPAS----GVIRTNKALDRESVATHDLKAVA----IDG---GTPPQSSTVI 672 D G F I S G+I +K LD E+ +++ L+ A +D + P S Sbjct: 264 D-GLGIFSITTDSHTQEGLITLHKNLDFETKSSYMLRVEASNLYVDARFLSSGPFSDVAT 322 Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 V + ++++ D PPVF S +SE + +GT +G + A DPD Sbjct: 323 VRLLVQNV-DEPPVFHSSVSWMMVSEAAAVGTEVGSVLARDPD 364 Score = 140 bits (340), Expect = 4e-31 Identities = 154/533 (28%), Positives = 222/533 (41%), Gaps = 81/533 (15%) Query: 283 DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG 342 D D+G + ++ Y +T + G + +ID +G ++ + +LDRE QA Y L A + Sbjct: 33 DVDKG-DGQVRYVLTGE---GAASI-FSIDESTGDIHATRRLDREQQAYYTLRAQARNR- 86 Query: 343 DPPR--SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDN--- 397 D R + F+ G Y +AE P GT VVT+ ATDAD+ Sbjct: 87 DTNRLVEPESQFIIKVQDVNDNEPKFLDGPYTARVAERSPVGTSVVTVVATDADDPTYGN 146 Query: 398 --RLHYEITGGNTRGRFSITSQNGRGLITVAQP-LDFKQERRYVLTVSATDS----GGRS 450 RL Y I G FS+ + G ++ A P LD + ++L V A D GG S Sbjct: 147 SARLMYSILQGQPY--FSVEPKTG--VVRTALPDLDREVRDSHLLVVQAKDMIGQIGGLS 202 Query: 451 DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSS 510 + V + +TD N+ P F Y SV E + T V + A D D G NA++ Y + Sbjct: 203 GSTSVTVILTDVNDNPPHFPRRSYQFSVRESELVSTVVAKIRAVDPDEGPNAELDYRI-- 260 Query: 511 EISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPS-------LSD 563 + + + + Q G IT +K LD ET S Y+L V A + V + SD Sbjct: 261 -LDGDGLGIFSITTDSHTQEGLITLHKNLDFETKSSYMLRVEASNLYVDARFLSSGPFSD 319 Query: 564 TTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV------------- 610 V + V +V D PVF + + E A VGT V V A D D Sbjct: 320 VATVRLLVQNV-DEPPVFHSSVSWMMVSEAAAVGTEVGSVLARDPDATNSPIRISADAAP 378 Query: 611 ---------GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID 661 L Y +D + E F ID +GVI T + LDRE+VA H++ VA + Sbjct: 379 PLTRCWCPNSLGSSCRYSIDRQSNLERYFHIDSGTGVITTAQPLDRETVAVHNITVVATE 438 Query: 662 GG-----------------------TPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISE 698 P + +V I + D+ND+PP D TF + E Sbjct: 439 RQHFLAVHSCLFSAWVTSCLVLMPVDPSLTGKAVVLISVTDVNDNPPSLAIDYDTF-VCE 497 Query: 699 NSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDK-AELVT 750 NS G + + A D DE P H+ + + S R D A ++T Sbjct: 498 NSEPGQIVQTLSAVDRDE-PEEGQHFLFSLSEAGQNLSFTLRDNKDNTASILT 549 Score = 133 bits (321), Expect = 8e-29 Identities = 109/320 (34%), Positives = 155/320 (48%), Gaps = 24/320 (7%) Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDT-TDVEISVVDVNDNEPVFK 582 F I+ TG I + LDRE + Y L AR+ L + + I V DVNDNEP F Sbjct: 54 FSIDESTGDIHATRRLDREQQAYYTLRAQARNRDTNRLVEPESQFIIKVQDVNDNEPKFL 113 Query: 583 QQLYTANIMEDALVGTSVSQVGATDAD---VGLNGRIHYELDPKDREEGSFVIDPASGVI 639 YTA + E + VGTSV V ATDAD G + R+ Y + + + F ++P +GV+ Sbjct: 114 DGPYTARVAERSPVGTSVVTVVATDADDPTYGNSARLMYSIL---QGQPYFSVEPKTGVV 170 Query: 640 RTNKA-LDRESVATHDLKAVAID--GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYI 696 RT LDRE +H L A D G S + V + + D+ND+PP F F + Sbjct: 171 RTALPDLDREVRDSHLLVVQAKDMIGQIGGLSGSTSVTVILTDVNDNPPHFPRRSYQFSV 230 Query: 697 SENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDY 756 E+ + T + +IRA DPDEGPNA + Y I GD FS+ T + + + +LD+ Sbjct: 231 RESELVSTVVAKIRAVDPDEGPNAELDYRILDGDGLGIFSITTDSHTQEGLITLHKNLDF 290 Query: 757 ESPRKKYELVIRA----------ASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKD 806 E+ + Y L + A +S P + V +LV +V D PV + + + Sbjct: 291 ET-KSSYMLRVEASNLYVDARFLSSGPFSDVATVRLLVQNV-DEPPVFHS-SVSWMMVSE 347 Query: 807 CFPVG-PFGRVPAYDADVTD 825 VG G V A D D T+ Sbjct: 348 AAAVGTEVGSVLARDPDATN 367 Score = 113 bits (273), Expect = 5e-23 Identities = 81/258 (31%), Positives = 133/258 (51%), Gaps = 12/258 (4%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +F ID +G + LDRE+ A YT+ +A ++ + + + + + + D NDN P Sbjct: 53 IFSIDESTGDIHATRRLDREQQAYYTLRAQARNRDT--NRLVEPESQFIIKVQDVNDNEP 110 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDAD---VGANSAIRYAIIGGNTQMQFSIDSL 205 +F + YT V E V + + + ATDAD G ++ + Y+I+ G Q FS++ Sbjct: 111 KFLDGPYTARVAERSPVGTS--VVTVVATDADDPTYGNSARLMYSILQG--QPYFSVEPK 166 Query: 206 SGDV-SLVKTLDYEQVRSYRLVIRAQD--GGSPSRSNTTQLLINIRDVNDNAPRFYTSLF 262 +G V + + LD E S+ LV++A+D G S +T + + + DVNDN P F + Sbjct: 167 TGVVRTALPDLDREVRDSHLLVVQAKDMIGQIGGLSGSTSVTVILTDVNDNPPHFPRRSY 226 Query: 263 QESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSG 322 Q SV E+ + + +++A D DEG NAEL Y + D D G + + G + Sbjct: 227 QFSVRESELVSTVVAKIRAVDPDEGPNAELDYRILDGDGLGIFSITTDSHTQEGLITLHK 286 Query: 323 QLDRETQAKYQLLVTATD 340 LD ET++ Y L V A++ Sbjct: 287 NLDFETKSSYMLRVEASN 304 Score = 99.1 bits (236), Expect = 2e-18 Identities = 106/364 (29%), Positives = 167/364 (45%), Gaps = 59/364 (16%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQD---IGKNAEVEYTIELVTA 67 I V D ND+ P F Y A V E + GT+V+T+ ATD D G +A + Y+I Sbjct: 100 IKVQDVNDNEPKFLDGPYTARVAERSPVGTSVVTVVATDADDPTYGNSARLMYSI----- 154 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTR-ASLDREKVARYTVLVKATDQASPV 126 Q F ++ ++G + T LDRE + ++V+A D + Sbjct: 155 ----------------LQGQPYFSVEPKTGVVRTALPDLDREVRDSHLLVVQAKDMIGQI 198 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 LS + ++ V + D NDN P F ++Y SV E V + V+AKI+A D D G N+ Sbjct: 199 GG-LSGSTSVTVILTDVNDNPPHFPRRSYQFSVRESELV--STVVAKIRAVDPDEGPNAE 255 Query: 187 IRYAIIGGNTQMQFSIDSLS----GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR----- 237 + Y I+ G+ FSI + S G ++L K LD+E SY L + A + +R Sbjct: 256 LDYRILDGDGLGIFSITTDSHTQEGLITLHKNLDFETKSSYMLRVEASNLYVDARFLSSG 315 Query: 238 --SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADE-----GVNA 290 S+ + + +++V D P F++S+ VSE +G + V A D D ++A Sbjct: 316 PFSDVATVRLLVQNV-DEPPVFHSSVSWMMVSEAAAVGTEVGSVLARDPDATNSPIRISA 374 Query: 291 ELTYTMT--------------DKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLV 336 + +T D N++ ID +G + T+ LDRET A + + V Sbjct: 375 DAAPPLTRCWCPNSLGSSCRYSIDRQSNLERYFHIDSGTGVITTAQPLDRETVAVHNITV 434 Query: 337 TATD 340 AT+ Sbjct: 435 VATE 438 Score = 56.4 bits (130), Expect = 1e-05 Identities = 89/386 (23%), Positives = 145/386 (37%), Gaps = 66/386 (17%) Query: 15 DCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPED 74 D ND+ P F + Y+ SVRE T V ++A D D G NAE++Y I L+ + Sbjct: 213 DVNDNPPHFPRRSYQFSVRESELVSTVVAKIRAVDPDEGPNAELDYRI-------LDGDG 265 Query: 75 AXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKAT----DQASPVSDRL 130 Q+ G + +LD E + Y + V+A+ D S Sbjct: 266 LGIFSITTDSHTQE--------GLITLHKNLDFETKSSYMLRVEASNLYVDARFLSSGPF 317 Query: 131 SSTATIHVNIIDDNDNYPQFSEKTYTVSVDE--------------DISVTDNPVIAKIKA 176 S AT+ + ++ + D P F + V E D T++P+ A Sbjct: 318 SDVATVRL-LVQNVDEPPVFHSSVSWMMVSEAAAVGTEVGSVLARDPDATNSPIRISADA 376 Query: 177 TD------ADVGANSAIRYAI-IGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRA 229 S+ RY+I N + F IDS +G ++ + LD E V + + + A Sbjct: 377 APPLTRCWCPNSLGSSCRYSIDRQSNLERYFHIDSGTGVITTAQPLDRETVAVHNITVVA 436 Query: 230 QDGG-----------------------SPSRSNTTQLLINIRDVNDNAPRFYTSLFQESV 266 + PS + +LI++ DVNDN P + V Sbjct: 437 TERQHFLAVHSCLFSAWVTSCLVLMPVDPSLTGKAVVLISVTDVNDNPPSLAID-YDTFV 495 Query: 267 SENVPIGYSIVRVQAYDADEGVNAE-LTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLD 325 EN G + + A D DE + +++++ + L D + + G Sbjct: 496 CENSEPGQIVQTLSAVDRDEPEEGQHFLFSLSEAGQNLSFTLRDNKDNTASILTRPGGFL 555 Query: 326 RETQAKYQLLVTATDGGDPPRSATAT 351 + Q + L V +D PP S+T T Sbjct: 556 QRDQLLHLLPVVISDSSRPPLSSTNT 581 >UniRef50_A6E164 Cluster: Large exoprotein; n=2; cellular organisms|Rep: Large exoprotein - Roseovarius sp. TM1035 Length = 5082 Score = 149 bits (362), Expect = 8e-34 Identities = 130/434 (29%), Positives = 207/434 (47%), Gaps = 37/434 (8%) Query: 373 VELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK 432 V +AED T + T + TD D + L Y I+ GN G F I + G + Q LD + Sbjct: 2949 VTVAEDLDAATVIATASGTDVDLSDVLSYSISAGNDAGLFEIDATTGDISLVAGQSLDAE 3008 Query: 433 QERRYVLTVSATDSGGRSDTAMVQINITDANN---YAPVFENAPYTASVFEDAPIGTTVL 489 + +VLTV+ +D G +DT + +N+TD ++ APV + SV E+A +GT + Sbjct: 3009 TDIEHVLTVTVSDGNGGTDTQEITVNVTDVDDNLTTAPVDADGVAGGSVDENAALGTVGI 3068 Query: 490 VVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTG--AITTNKLLDRETMSGY 547 ++TD+D+ A ITY++ + + FVI+ +TG ++ + +DRET S Sbjct: 3069 TAASTDADITSGA-ITYAI---VGGTGATN----FVIDAETGVVSVASGANIDRETGSSL 3120 Query: 548 LLTVTARD-GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQV-GA 605 + V A G S++ T + I+ V+ D + E+A GT V V A Sbjct: 3121 TIDVQATPANGAASVTSTFTITINDVNEFDVTTPVDSNAAANEVSENAGPGTLVGIVASA 3180 Query: 606 TDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKAL-----DRESVATHDL--KAV 658 +DAD NG + Y L D G F ID A+G +R + A D E+ +H + +A+ Sbjct: 3181 SDADATTNG-VTYSL--TDSAGGIFEIDAATGEVRLSTAAMAPRPDFETAESHTITVQAM 3237 Query: 659 AIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 + DG T + T I I D ND+ PVF + ++EN T++ + A D D Sbjct: 3238 SADGSTSTEDFT----ITILDANDTAPVFAINAAQ-SVAENE---TSVVRLSATDVDTDQ 3289 Query: 719 NAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESP---RKKYELVIRAASPPLW 775 + + ++I GGDD +F + +G E V+ D + + Y +V+ A Sbjct: 3290 SG-ISFTIVGGDDQAAFRVVEDEGVYTLEFVSAPDFEMPTDMGGNNIYNVVVEAFDGTNM 3348 Query: 776 NDVRVEILVTDVND 789 + I VTDVN+ Sbjct: 3349 TEQAFAITVTDVNE 3362 Score = 122 bits (293), Expect = 2e-25 Identities = 141/516 (27%), Positives = 231/516 (44%), Gaps = 34/516 (6%) Query: 114 TVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK 173 T++V T A +S+ S+T T V I N + V+V ED+ VIA Sbjct: 2906 TLVVTYTLTADDLSETDSATDTQTVTITITGTNDSPVASAADGVTVAEDLDAAT--VIAT 2963 Query: 174 IKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLV--KTLDYEQVRSYRLVIRAQD 231 TD D+ + + Y+I GN F ID+ +GD+SLV ++LD E + L + D Sbjct: 2964 ASGTDVDL--SDVLSYSISAGNDAGLFEIDATTGDISLVAGQSLDAETDIEHVLTVTVSD 3021 Query: 232 GGSPSRSNTTQLLINIRDVNDN---APRFYTSLFQESVSENVPIGYSIVRVQAYDADEGV 288 G ++T ++ +N+ DV+DN AP + SV EN +G + + DAD Sbjct: 3022 GN--GGTDTQEITVNVTDVDDNLTTAPVDADGVAGGSVDENAALGTVGITAASTDADI-T 3078 Query: 289 NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD-GGDPPRS 347 + +TY + TG + I + V + +DRET + + V AT G + Sbjct: 3079 SGAITYAIVGG--TGATNFVIDAETGVVSVASGANIDRETGSSLTIDVQATPANGAASVT 3136 Query: 348 ATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV-VTLTATDAD-EDNRLHYEITG 405 +T T E++E+ PGT V + +A+DAD N + Y +T Sbjct: 3137 STFTITINDVNEFDVTTPVDSNAAANEVSENAGPGTLVGIVASASDADATTNGVTYSLT- 3195 Query: 406 GNTRGRFSITSQNGRGLITVAQPL---DFKQERRYVLTVSATDSGGRSDTAMVQINITDA 462 + G F I + G ++ A DF+ + +TV A + G + T I I DA Sbjct: 3196 DSAGGIFEIDAATGEVRLSTAAMAPRPDFETAESHTITVQAMSADGSTSTEDFTITILDA 3255 Query: 463 NNYAPVFE-NAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHD 521 N+ APVF NA SV E+ T+V+ +SATD D + I++++ A + Sbjct: 3256 NDTAPVFAINA--AQSVAENE---TSVVRLSATDVDTD-QSGISFTIVGGDDQAAFRVVE 3309 Query: 522 QQFVINPQ-TGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580 + V + A D + Y + V A DG ++++ I+V DVN+ Sbjct: 3310 DEGVYTLEFVSAPDFEMPTDMGGNNIYNVVVEAFDG--TNMTEQA-FAITVTDVNEAPTA 3366 Query: 581 FKQQLYTANIMEDALVGT--SVSQVGATDADVGLNG 614 T+ + E++++G+ V+ + TD +G+NG Sbjct: 3367 VSLDNTTSTLAENSVIGSGIKVADITITDDALGVNG 3402 Score = 97.1 bits (231), Expect = 6e-18 Identities = 143/571 (25%), Positives = 228/571 (39%), Gaps = 47/571 (8%) Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWV-YTSGQ 323 S ++ V + + G + +L+ ++ GN ID +G + +GQ Sbjct: 2944 SAADGVTVAEDLDAATVIATASGTDVDLSDVLSYSISAGNDAGLFEIDATTGDISLVAGQ 3003 Query: 324 -LDRETQAKYQLLVTATDG-GDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPP 381 LD ET ++ L VT +DG G G + E+ Sbjct: 3004 SLDAETDIEHVLTVTVSDGNGGTDTQEITVNVTDVDDNLTTAPVDADGVAGGSVDENAAL 3063 Query: 382 GTPVVTLTATDAD-EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLT 440 GT +T +TDAD + Y I GG F I ++ G +++VA + +E LT Sbjct: 3064 GTVGITAASTDADITSGAITYAIVGGTGATNFVIDAETG--VVSVASGANIDRETGSSLT 3121 Query: 441 --VSATDSGGRSD-TAMVQINITDANNY---APVFENAPYTASVFEDAPIGTTV-LVVSA 493 V AT + G + T+ I I D N + PV NA V E+A GT V +V SA Sbjct: 3122 IDVQATPANGAASVTSTFTITINDVNEFDVTTPVDSNAAAN-EVSENAGPGTLVGIVASA 3180 Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQF-VINPQTGAITTNKLLDRETMSGYLLTVT 552 +D+D N +TYSL+ S + D + T A+ D ET + +TV Sbjct: 3181 SDADATTNG-VTYSLTD--SAGGIFEIDAATGEVRLSTAAMAPRP--DFETAESHTITVQ 3235 Query: 553 ARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL 612 A + T D I+++D ND PVF ++ E+ TSV ++ ATD D Sbjct: 3236 AMSAD--GSTSTEDFTITILDANDTAPVFAINA-AQSVAENE---TSVVRLSATDVDTDQ 3289 Query: 613 NGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRE---SVATHDLKAVAIDGGTPPQSS 669 +G + D+ V D + A D E + +++ V ++ + Sbjct: 3290 SGISFTIVGGDDQAAFRVVEDEGVYTLEFVSAPDFEMPTDMGGNNIYNVVVEAFDGTNMT 3349 Query: 670 TVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT--TIGEIRAHDPDEGPNAVVHYSIK 727 I + D+N++P D T ++ENS IG+ + +I D G N V ++ Sbjct: 3350 EQAFAITVTDVNEAPTAVSLDNTTSTLAENSVIGSGIKVADITITDDALGVNGV---TLT 3406 Query: 728 GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLWNDVRVEILVTDV 787 G D + + T G ++L Y +E A + +N V VE+ V Sbjct: 3407 GADAAFFAVVSTDTG---------LELHYVGEAPNFEAPADAGADNSFN-VTVEVDDGTV 3456 Query: 788 NDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA 818 D DF + + + PV +VPA Sbjct: 3457 GDTPDATTDFTLTVTDVNEA-PVA--NQVPA 3484 Score = 76.6 bits (180), Expect = 9e-12 Identities = 135/565 (23%), Positives = 224/565 (39%), Gaps = 68/565 (12%) Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 V+D T T+ VN+ + N ++ +S ED +++ + ATD D Sbjct: 4277 VTDGNGGTDTVVVNVTVNAVNDAPVAQADAAISTGEDQAISGT-----VTATDVD---GD 4328 Query: 186 AIRYAIIGGNTQMQFSID-SLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 ++ +A+ G S+ S +G + D+ ++ + + +GG+ +T + Sbjct: 4329 SLSFALATGGAPANGSVTISANGGYTYTPDADFNGTDAFTVSVTDGNGGT----DTVVVN 4384 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 + + VND AP S E+ I ++ A D D L++ + N Sbjct: 4385 VTVNAVND-APVAQADA-AISTGEDQAISGTVT---ATDVD---GDSLSFALASGGAPAN 4436 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXX 364 +TI G+ YT D + V+ TDG T T Sbjct: 4437 GS--VTISANGGYTYTP---DADFNGTDAFTVSVTDGN----GGTDTVVVNVTVNAVNDA 4487 Query: 365 XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLIT 424 + ED+ T+TATD D D+ L + + G S+T + G T Sbjct: 4488 PVAQADAAISTGEDQAISG---TVTATDVDGDS-LSFALATGGAPANGSVTV-SANGGYT 4542 Query: 425 VAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 DF + TVS TD G +DT +V + + +A N APV + A S ED I Sbjct: 4543 YTPDADFNGTDAF--TVSVTDGNGGTDTVVVNVTV-NAVNDAPVAQ-ADAAISTGEDQAI 4598 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 T V+ATD D ++++L+ + A A+ N G T D Sbjct: 4599 SGT---VTATDVD---GDSLSFALA---TGGAPANGSVTVSAN---GGYTYTPDADFNGT 4646 Query: 545 SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT--SVSQ 602 + ++VT +GG +DT V ++V VND PV T ++ EDA + V+ Sbjct: 4647 DAFTVSVTDGNGG----TDTVVVNVTVNAVND-APVVTLANVTTDVDEDADTTSRIKVAD 4701 Query: 603 VGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAID- 661 + +D + G+N L + F I + +R +LD E+ A D+ D Sbjct: 4702 IVVSDDEQGIN-----TLALAGADAALFEIVGTALFLRAGASLDFETKAQLDVSVTVNDA 4756 Query: 662 --GGTPPQSSTVIVHIKIEDINDSP 684 GGTP T + + + D+++ P Sbjct: 4757 SVGGTP--DGTASLSLTVNDVDEGP 4779 Score = 72.9 bits (171), Expect = 1e-10 Identities = 166/704 (23%), Positives = 265/704 (37%), Gaps = 79/704 (11%) Query: 36 ASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXXXXXXVQDVFRIDGR 95 A+ T+ T + T QD G VT D P +D RI Sbjct: 4072 AAGVTSTATFQYTVQDSGSAQSTTTVTVQVTGDNDAPTAVQVTLLASN---EDTVRIITE 4128 Query: 96 SGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTY 155 + L + +D V T L + S V D T T ++ D+ D FS Y Sbjct: 4129 AQLLSGASDVDTGAVLEITALALTSGNGSLV-DNEDGTWTYTPDLNDNGD--VTFS---Y 4182 Query: 156 TVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQM---QFSIDSLSGDVSLV 212 TVS D ++ T + + + DA V A AI G Q + + GD SL Sbjct: 4183 TVS-DGLLTATASATLDLLPVNDAPVAQADA---AISTGEDQAISGTVTATDVDGD-SLS 4237 Query: 213 KTLDYEQVRSYRLVIRAQDGG---SPSR--SNTTQLLINIRDVNDNAPRFYTSLFQESVS 267 L + V + +GG +P + T +++ D N ++ +V+ Sbjct: 4238 FALASGGAPANGSVTISANGGYTYTPDADFNGTDAFTVSVTDGNGGTDTVVVNVTVNAVN 4297 Query: 268 ENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY------TGNVDL--PITIDPRSGWVY 319 + P+ + + + D+ ++ +T T D D TG +TI G+ Y Sbjct: 4298 D-APVAQADAAISTGE-DQAISGTVTATDVDGDSLSFALATGGAPANGSVTISANGGYTY 4355 Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDE 379 T D + V+ TDG T T + ED+ Sbjct: 4356 TP---DADFNGTDAFTVSVTDGN----GGTDTVVVNVTVNAVNDAPVAQADAAISTGEDQ 4408 Query: 380 PPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVL 439 T+TATD D D+ L + + G S+T + G T DF + Sbjct: 4409 AISG---TVTATDVDGDS-LSFALASGGAPANGSVTI-SANGGYTYTPDADFNGTDAF-- 4461 Query: 440 TVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVG 499 TVS TD G +DT +V + + N+ APV + A S ED I TV +ATD D Sbjct: 4462 TVSVTDGNGGTDTVVVNVTVNAVND-APVAQ-ADAAISTGEDQAISGTV---TATDVD-- 4514 Query: 500 INAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVP 559 ++++L++ A A+ N G T D + ++VT +GG Sbjct: 4515 -GDSLSFALAT---GGAPANGSVTVSAN---GGYTYTPDADFNGTDAFTVSVTDGNGG-- 4565 Query: 560 SLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYE 619 +DT V ++V VND PV + + + A+ GT V ATD D + + Sbjct: 4566 --TDTVVVNVTVNAVND-APVAQADAAISTGEDQAISGT----VTATDVD---GDSLSFA 4615 Query: 620 LDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIED 679 L V A+G D + +GGT TV+V++ + Sbjct: 4616 LATGGAPANGSVTVSANGGYTYTPDADFNGTDAFTVSVTDGNGGT----DTVVVNVTVNA 4671 Query: 680 INDSPPVFESDCLTFYISENSPIGTTI--GEIRAHDPDEGPNAV 721 +ND+P V ++ +T + E++ + I +I D ++G N + Sbjct: 4672 VNDAPVVTLAN-VTTDVDEDADTTSRIKVADIVVSDDEQGINTL 4714 Score = 71.7 bits (168), Expect = 3e-10 Identities = 176/719 (24%), Positives = 265/719 (36%), Gaps = 84/719 (11%) Query: 160 DEDISVTDNPVI--AKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVK--TL 215 D D+ + D P I A T V R I G + ++ S +GD +L +L Sbjct: 4016 DTDVDINDIPTIVDASSSVTATAVATADGFRITTIDG---VVVNL-SANGDYTLTAPDSL 4071 Query: 216 DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275 + QD GS +TT + + + ND +L + I + Sbjct: 4072 AAGVTSTATFQYTVQDSGSAQ--STTTVTVQVTGDNDAPTAVQVTLLASNEDTVRIITEA 4129 Query: 276 IVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSG-WVYTSGQLDRETQAKYQL 334 + A D D G E+T +GN L +D G W YT D Sbjct: 4130 QLLSGASDVDTGAVLEITALALT---SGNGSL---VDNEDGTWTYTP---DLNDNGDVTF 4180 Query: 335 LVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD 394 T +DG TAT + ED+ T+TATD D Sbjct: 4181 SYTVSDG-----LLTATASATLDLLPVNDAPVAQADAAISTGEDQAISG---TVTATDVD 4232 Query: 395 EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAM 454 D+ L + + G S+T + G T DF + TVS TD G +DT + Sbjct: 4233 GDS-LSFALASGGAPANGSVTI-SANGGYTYTPDADFNGTDAF--TVSVTDGNGGTDTVV 4288 Query: 455 VQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISN 514 V + + +A N APV + A S ED I T V+ATD D ++++L+ + Sbjct: 4289 VNVTV-NAVNDAPVAQ-ADAAISTGEDQAISGT---VTATDVD---GDSLSFALA---TG 4337 Query: 515 EAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDV 574 A A+ N G T D + ++VT +GG +DT V ++V V Sbjct: 4338 GAPANGSVTISAN---GGYTYTPDADFNGTDAFTVSVTDGNGG----TDTVVVNVTVNAV 4390 Query: 575 NDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP 634 ND PV + + + A+ GT V ATD D + + L V Sbjct: 4391 ND-APVAQADAAISTGEDQAISGT----VTATDVD---GDSLSFALASGGAPANGSVTIS 4442 Query: 635 ASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF 694 A+G D + +GGT TV+V++ + +ND+ PV ++D Sbjct: 4443 ANGGYTYTPDADFNGTDAFTVSVTDGNGGT----DTVVVNVTVNAVNDA-PVAQADA-AI 4496 Query: 695 YISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDL 754 E+ I G + A D D G + + G + S ++ G D Sbjct: 4497 STGEDQAIS---GTVTATDVD-GDSLSFALATGGAPANGSVTVSANGG-----YTYTPDA 4547 Query: 755 DYESPRKKYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG 814 D+ + + + + + V V + V VND APV + I G Sbjct: 4548 DFNG-TDAFTVSVTDGNGGT-DTVVVNVTVNAVND-APVAQADAAISTGEDQAIS----G 4600 Query: 815 RVPAYDADVTDKLQYRILSGN-NANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDG 872 V A D D D L + + +G AN + G T +P + N T VSVTDG Sbjct: 4601 TVTATDVD-GDSLSFALATGGAPANGSVTVSANGGYTYTPDADFNGTDAFT--VSVTDG 4656 Score = 49.6 bits (113), Expect = 0.001 Identities = 90/379 (23%), Positives = 143/379 (37%), Gaps = 43/379 (11%) Query: 225 LVIRAQDGGSPSR----SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQ 280 L + DGGS ++ + I + VND AP + E + +++ Sbjct: 2260 LTMTTDDGGSTGEGGALTDIDTVTITVNPVND-APVVEGPVSAEQTEDAEGFTVNLLS-G 2317 Query: 281 AYDADEGVNAELTYTMTDKDYTGNVDLP-----ITIDPRSGWVYTSGQLDRETQAKYQLL 335 A D D G ++ M D V + +T+DP + YT+ + Y Sbjct: 2318 ASDVDTGDVLTVSGLMLDSGDDSGVTVSMDGNSLTVDPDA---YTALAVGESAVITYSYT 2374 Query: 336 VTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADE 395 VT +GG+ ++AT T P V+ A D+ + TL +D D Sbjct: 2375 VTDGNGGEVSQTATITITGANDGPVLEDVTTAPAI--VDTAGDDTLSSVSDTLVGSDVDN 2432 Query: 396 DNRLHYEITG-----GNT--RGRFSITSQNGRGLITVA------QPLDFKQERRYVLTVS 442 L Y I+G G T G++ + G T Q L E T+ Sbjct: 2433 GAVLTYAISGQEPVMGETSLEGKYGTLTVLSDGSYTYTPDAAKLQGLAADAEPNETFTIV 2492 Query: 443 ATDSGGRSDTAMVQINITDANNYAPVFE----NAPYTASVFEDAPIGTTVLVVSATDSDV 498 TD G DTA + ++IT AN+ + N TA+ + A G T +SATD D Sbjct: 2493 VTDEHGAFDTATLTVDITPANDTPELASVDAINITDTAAADDFAAQGGT---LSATDRDS 2549 Query: 499 GINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGV 558 G + YS++ + E Q F + A+ T L+ + T+T + G Sbjct: 2550 GHVDAMVYSIAGQEVAEGAT--SQTFYFDRVGNAVVTEAPLNGVELG----TLTVQSSGA 2603 Query: 559 PSLSDTTDVEISVVDVNDN 577 S + D I+ + + N Sbjct: 2604 YSF-EPNDAGINSLRADQN 2621 Score = 39.1 bits (87), Expect = 1.7 Identities = 35/127 (27%), Positives = 55/127 (43%), Gaps = 9/127 (7%) Query: 376 AEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQER 435 AEDE G T+ A D D+ L + I G++ S+T G + +F Sbjct: 3621 AEDE--GAITGTIVADDVDDGAILGFSIEDGDSAANGSVTVDPNTGTWSYTPDANFNGVD 3678 Query: 436 RYVLTVSATDSGGRSDTAMVQINITDANNYAPVFEN----APYTASVFEDAPIGTTVLV- 490 + +TVS D G S T +V + +T N+ + + A + +V AP+ T + Sbjct: 3679 SFTVTVS--DGLGGSVTQVVDVTVTAVNDATEIDVSSQVAATHVEAVDAAAPVATLIAAQ 3736 Query: 491 VSATDSD 497 S TD D Sbjct: 3737 ASLTDVD 3743 Score = 37.5 bits (83), Expect = 5.3 Identities = 97/471 (20%), Positives = 175/471 (37%), Gaps = 42/471 (8%) Query: 273 GYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKY 332 G + V DAD+ A + T++D T L D + ++ QLD + Sbjct: 190 GDQTLTVTGIDADQ---ASVVVTVSDGTTTVTATLGAITDGSATATLSAAQLDTLSDGTL 246 Query: 333 QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATD 392 VT TD ++T T V+ + V + D Sbjct: 247 TATVTVTDVSTNVATSTDTIALDTIADAAPNLSVAFEGAGVDDSTFNAGEAIQVAFSGID 306 Query: 393 ADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT 452 AD L TGG + +TS + + + +D + +T+ TD+ G +T Sbjct: 307 ADATGTLTITSTGGGSVVVAGLTSVSSSPISLDSMQMDALSDGTLSVTLDVTDTAG--NT 364 Query: 453 AMVQINITDANNYAPVFENAPYT------ASVFEDAPIGTTVLVVSATDS-DVGINAQIT 505 A VQ N D + AP+ + +V + G+ L ++ ++ D ++ +T Sbjct: 365 AQVQSNGFDLDASAPMIASVTLAGGSGVEGTVIDGDVDGSVTLTIAFNEAMDTAVDPTVT 424 Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT-ARDGGVPSLSDT 564 +S S ++ + ++ + IT + ++ + V+ A+D +S Sbjct: 425 LDTASASS---FTEAERAWSMDGLSLTITYTVVDQNVDLAAITVGVSGAQDVAGNVISAV 481 Query: 565 TDVEISVVDVNDNEPVFKQQLYTANIMED--ALVGTSV---SQVGATDADVGLNG----R 615 ++V ++ + + A I + A GT + GA L G Sbjct: 482 SEVATGTAIDTESTASETESVTIAEIPDQNAATTGTPIVLAKLSGADGTTYALTGEAAVN 541 Query: 616 IHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVHI 675 H E+ D E+G V + R L+ E+ + D+ D +S ++ I Sbjct: 542 AHVEI-VSDGEDGFMVQIIDTEAARGFFDLE-ENGPSFDISVTGTDNAGNTTAS--VLSI 597 Query: 676 KIEDINDSPPVF--ESDCLTFYISEN---------SPIGTTIGEIRAHDPD 715 + D+ND+P + E+D LT ++E +P GTT G HD D Sbjct: 598 TLTDLNDAPELVPGEND-LTGTVTEREDGVLGENATPFGTT-GTFGVHDDD 646 >UniRef50_A7T102 Cluster: Predicted protein; n=1; Nematostella vectensis|Rep: Predicted protein - Nematostella vectensis Length = 341 Score = 149 bits (361), Expect = 1e-33 Identities = 110/359 (30%), Positives = 166/359 (46%), Gaps = 32/359 (8%) Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259 FS++S++G+++L LD+E RSY LV+ A+D G P + T ++I + D++D PRF Sbjct: 4 FSLNSVNGELTLGGPLDFEVARSYMLVVIAEDLGVPKLESRTTVIIEVTDISDMPPRFLQ 63 Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVY 319 S + + + EN PI V + Y + D + IDP SG +Y Sbjct: 64 SSYLKEIEENTPIP--------------VFRRVLYHLVGAD-----SVKFAIDPTSGTLY 104 Query: 320 TSGQLDRETQAKYQLLVTATDGGDPPR-SATATXXXXXXXXXXXXXXFMPGQYEVELAED 378 + LD E Q + V AT+ + SA A+ F Y + E+ Sbjct: 105 INKTLDYEKQINFTFDVVATETDTSEKFSANASVTLTLININDNKPMFAKSSYNYTMDEE 164 Query: 379 EPPGTPVVTLTATDADEDN--RLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERR 436 PGT + +TATDAD L YE+ GG FS+ + NG I+ AQ LD+ + Sbjct: 165 ITPGTHIADITATDADLGTFGALTYELRGGQA-AYFSVNADNGT--ISAAQILDYDTLPQ 221 Query: 437 YVLTVSATDSGG---RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 Y ++ A D GG A V + + D N+ P F PYT+ + E+ P GT V V+A Sbjct: 222 YQFSLMAKDGGGFYQEIAIATVTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTA 281 Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVT 552 TD D G N ++ S+ H D Q +N T ++ D T++ + VT Sbjct: 282 TDKDSGENGRV----SAYDHGVPSRHRDVQLTVNVLDENDNTPQITDGLTITTNISEVT 336 Score = 127 bits (307), Expect = 4e-27 Identities = 92/316 (29%), Positives = 151/316 (47%), Gaps = 32/316 (10%) Query: 412 FSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGG---RSDTAMVQINITDANNYAPV 468 FS+ S NG +T+ PLDF+ R Y+L V A D G S T ++ I +TD ++ P Sbjct: 4 FSLNSVNGE--LTLGGPLDFEVARSYMLVVIAEDLGVPKLESRTTVI-IEVTDISDMPPR 60 Query: 469 FENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINP 528 F + Y + E+ PI + ++ Y L V +F I+P Sbjct: 61 FLQSSYLKEIEENTPIP--------------VFRRVLYHL--------VGADSVKFAIDP 98 Query: 529 QTGAITTNKLLDRETMSGYLLTVTARDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYT 587 +G + NK LD E + V A + S V ++++++NDN+P+F + Y Sbjct: 99 TSGTLYINKTLDYEKQINFTFDVVATETDTSEKFSANASVTLTLININDNKPMFAKSSYN 158 Query: 588 ANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDR 647 + E+ GT ++ + ATDAD+G G + YEL + + F ++ +G I + LD Sbjct: 159 YTMDEEITPGTHIADITATDADLGTFGALTYEL--RGGQAAYFSVNADNGTISAAQILDY 216 Query: 648 ESVATHDLKAVAIDGGTPPQSSTV-IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTI 706 +++ + +A DGG Q + V + ++D+ND+ P F T I+EN P GT + Sbjct: 217 DTLPQYQFSLMAKDGGGFYQEIAIATVTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIV 276 Query: 707 GEIRAHDPDEGPNAVV 722 ++ A D D G N V Sbjct: 277 FQVTATDKDSGENGRV 292 Score = 125 bits (302), Expect = 2e-26 Identities = 70/205 (34%), Positives = 115/205 (56%), Gaps = 6/205 (2%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F ID SG L +LD EK +T V AT+ + S++ S+ A++ + +I+ NDN P Sbjct: 94 FAIDPTSGTLYINKTLDYEKQINFTFDVVATE--TDTSEKFSANASVTLTLININDNKPM 151 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209 F++ +Y ++DE+I T IA I ATDAD+G A+ Y + GG FS+++ +G + Sbjct: 152 FAKSSYNYTMDEEI--TPGTHIADITATDADLGTFGALTYELRGGQAAY-FSVNADNGTI 208 Query: 210 SLVKTLDYEQVRSYRLVIRAQDGGSPSRSNT-TQLLINIRDVNDNAPRFYTSLFQESVSE 268 S + LDY+ + Y+ + A+DGG + + + ++DVNDN P F + ++E Sbjct: 209 SAAQILDYDTLPQYQFSLMAKDGGGFYQEIAIATVTVTLQDVNDNDPEFTGMPYTSDIAE 268 Query: 269 NVPIGYSIVRVQAYDADEGVNAELT 293 N+P G + +V A D D G N ++ Sbjct: 269 NLPAGTIVFQVTATDKDSGENGRVS 293 Score = 114 bits (275), Expect = 3e-23 Identities = 88/307 (28%), Positives = 148/307 (48%), Gaps = 29/307 (9%) Query: 315 SGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374 +G + G LD E Y L+V A D G P + T F+ Y E Sbjct: 10 NGELTLGGPLDFEVARSYMLVVIAEDLGVPKLESRTTVIIEVTDISDMPPRFLQSSYLKE 69 Query: 375 LAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQE 434 + E+ P PV R+ Y + G ++ +F+I +G + + + LD++++ Sbjct: 70 IEENTP--IPVF----------RRVLYHLVGADSV-KFAIDPTSGT--LYINKTLDYEKQ 114 Query: 435 RRYVLTVSATDSGGR---SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVV 491 + V AT++ S A V + + + N+ P+F + Y ++ E+ GT + + Sbjct: 115 INFTFDVVATETDTSEKFSANASVTLTLININDNKPMFAKSSYNYTMDEEITPGTHIADI 174 Query: 492 SATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTV 551 +ATD+D+G +TY E+ A+ F +N G I+ ++LD +T+ Y ++ Sbjct: 175 TATDADLGTFGALTY----ELRGGQAAY----FSVNADNGTISAAQILDYDTLPQYQFSL 226 Query: 552 TARDGG--VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDAD 609 A+DGG ++ T V +++ DVNDN+P F YT++I E+ GT V QV ATD D Sbjct: 227 MAKDGGGFYQEIAIAT-VTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKD 285 Query: 610 VGLNGRI 616 G NGR+ Sbjct: 286 SGENGRV 292 Score = 101 bits (243), Expect = 2e-19 Identities = 82/307 (26%), Positives = 139/307 (45%), Gaps = 27/307 (8%) Query: 90 FRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQ 149 F ++ +G L LD E Y ++V A D P +L S T+ + + D +D P+ Sbjct: 4 FSLNSVNGELTLGGPLDFEVARSYMLVVIAEDLGVP---KLESRTTVIIEVTDISDMPPR 60 Query: 150 FSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDV 209 F + +Y ++E+ + PV ++ Y ++G ++ ++F+ID SG + Sbjct: 61 FLQSSYLKEIEENTPI---PVFRRVL-------------YHLVGADS-VKFAIDPTSGTL 103 Query: 210 SLVKTLDYEQVRSYRL-VIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE 268 + KTLDYE+ ++ V+ + S S + + + ++NDN P F S + ++ E Sbjct: 104 YINKTLDYEKQINFTFDVVATETDTSEKFSANASVTLTLININDNKPMFAKSSYNYTMDE 163 Query: 269 NVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRET 328 + G I + A DAD G LTY + G +++ +G + + LD +T Sbjct: 164 EITPGTHIADITATDADLGTFGALTY-----ELRGGQAAYFSVNADNGTISAAQILDYDT 218 Query: 329 QAKYQLLVTATDGGD-PPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVT 387 +YQ + A DGG A AT F Y ++AE+ P GT V Sbjct: 219 LPQYQFSLMAKDGGGFYQEIAIATVTVTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQ 278 Query: 388 LTATDAD 394 +TATD D Sbjct: 279 VTATDKD 285 Score = 100 bits (240), Expect = 5e-19 Identities = 97/355 (27%), Positives = 146/355 (41%), Gaps = 37/355 (10%) Query: 524 FVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQ 583 F +N G +T LD E Y+L V A D GVP L T V I V D++D P F Q Sbjct: 4 FSLNSVNGELTLGGPLDFEVARSYMLVVIAEDLGVPKLESRTTVIIEVTDISDMPPRFLQ 63 Query: 584 QLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK 643 Y I E+ + + R+ Y L D + F IDP SG + NK Sbjct: 64 SSYLKEIEENT--------------PIPVFRRVLYHLVGADSVK--FAIDPTSGTLYINK 107 Query: 644 ALDRESVATHDLKAVAIDGGTPPQ-SSTVIVHIKIEDINDSPPVFESDCLTFYISENSPI 702 LD E VA + T + S+ V + + +IND+ P+F + + E Sbjct: 108 TLDYEKQINFTFDVVATETDTSEKFSANASVTLTLININDNKPMFAKSSYNYTMDEEITP 167 Query: 703 GTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYES-PRK 761 GT I +I A D D G + Y ++GG + FS+ G+ A + LDY++ P+ Sbjct: 168 GTHIADITATDADLGTFGALTYELRGG-QAAYFSVNADNGTISAAQI----LDYDTLPQY 222 Query: 762 KYELVIRAASPPLWNDV---RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPA 818 ++ L+ + + ++ V + + DVNDN P ++ + P G Sbjct: 223 QFSLMAKDGG-GFYQEIAIATVTVTLQDVNDNDPEFTGMPYT-SDIAENLPAGTI----V 276 Query: 819 YDADVTDKLQYRILSGNNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGV 873 + TDK SG N + + S QL NV +TDG+ Sbjct: 277 FQVTATDK-----DSGENGRVSAYDHGVPSRHRDVQLTVNVLDENDNTPQITDGL 326 Score = 39.9 bits (89), Expect = 0.99 Identities = 17/48 (35%), Positives = 26/48 (54%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEV 58 + + D ND+ P F Y + + E +GT V + ATD+D G+N V Sbjct: 245 VTLQDVNDNDPEFTGMPYTSDIAENLPAGTIVFQVTATDKDSGENGRV 292 >UniRef50_Q6R8F2 Cluster: Epithelial cadherin precursor (E-cadherin) (Cadherin-1) (CD324 antigen) [Contains: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3]; n=7; Laurasiatheria|Rep: Epithelial cadherin precursor (E-cadherin) (Cadherin-1) (CD324 antigen) [Contains: E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3] - Bos taurus (Bovine) Length = 882 Score = 149 bits (361), Expect = 1e-33 Identities = 120/401 (29%), Positives = 185/401 (46%), Gaps = 31/401 (7%) Query: 200 FSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYT 259 F I+ +G + + + LD EQ+ Y L A + +++I + D NDN P+F Sbjct: 205 FIIERETGWLKVTQPLDREQIAKYILFSHAVSSNGQAIEEPMEIVITVTDQNDNKPQFTQ 264 Query: 260 SLFQESVSENVPIGYSIVRVQAYDADEGVN---AELTYTMTDKDYTGNVDLPITIDPRSG 316 +F+ S E G S+++V A D D+ VN A + YT+ +D + TI+ +G Sbjct: 265 EVFKASALEGALPGTSVMQVTATDIDDEVNTYTAAIGYTIPAQDPMLPHNKMFTINKETG 324 Query: 317 --WVYTSGQLDRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE 374 V T+G LDRE+ Y L+V A D S TAT F P Y Sbjct: 325 VISVLTTG-LDRESFPTYTLMVQAADLNGEGLSTTATAVITVLDTNDNAPRFNPTTYVGS 383 Query: 375 LAEDEPPGTPVVTLTATDADEDN----RLHYEITGGNTRGRFSITSQ-NGRGLITVAQPL 429 + E+E + TLT TDAD+ N Y + N + +T G + A+ L Sbjct: 384 VPENE-ANVAITTLTVTDADDPNTPAWEAVYTVLNDNEKQFIVVTDPVTNEGTLKTAKGL 442 Query: 430 DFKQERRYVLTVSATDSGG-----RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 DF+ +++Y+L V+ T+ + TA V +++ D N AP+F V ED + Sbjct: 443 DFEAKQQYILYVAVTNVAPFEVTLPTSTATVTVDVIDVNE-APIFVPPQKRVEVPEDFGV 501 Query: 485 GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETM 544 G + +A + D + +ITY + + +N INP+TGAI+T LDRE + Sbjct: 502 GLEITSYTAREPDTFMEQKITYRIWRDTAN--------WLEINPETGAISTRAELDREDV 553 Query: 545 -----SGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPV 580 S Y + A D G P + T + + + DVNDN PV Sbjct: 554 DHVKNSTYTALIIATDNGSPPATGTGTLLLFLDDVNDNGPV 594 Score = 140 bits (339), Expect = 5e-31 Identities = 148/520 (28%), Positives = 235/520 (45%), Gaps = 51/520 (9%) Query: 391 TDADEDNRLHYEITGGNTR----GRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDS 446 ++ +++ ++ Y ITG G F I + G + V QPLD +Q +Y+L A S Sbjct: 180 SNKEKETQVFYSITGQRADTPPVGVFIIERETG--WLKVTQPLDREQIAKYILFSHAVSS 237 Query: 447 GGRS--DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN--- 501 G++ + + I +TD N+ P F + AS E A GT+V+ V+ATD D +N Sbjct: 238 NGQAIEEPMEIVITVTDQNDNKPQFTQEVFKASALEGALPGTSVMQVTATDIDDEVNTYT 297 Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL-LDRETMSGYLLTVTARDGGVPS 560 A I Y++ ++ + + H++ F IN +TG I+ LDRE+ Y L V A D Sbjct: 298 AAIGYTIPAQ---DPMLPHNKMFTINKETGVISVLTTGLDRESFPTYTLMVQAADLNGEG 354 Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620 LS T I+V+D NDN P F Y ++ E+ +++ + TDAD Sbjct: 355 LSTTATAVITVLDTNDNAPRFNPTTYVGSVPENE-ANVAITTLTVTDADDPNTPAWEAVY 413 Query: 621 DPKDREEGSFVI--DPAS--GVIRTNKALDRESVATHDLKAVAIDGGTPPQ----SSTVI 672 + E F++ DP + G ++T K LD E+ + L VA+ P + +ST Sbjct: 414 TVLNDNEKQFIVVTDPVTNEGTLKTAKGLDFEAKQQYILY-VAVTNVAPFEVTLPTSTAT 472 Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDS 732 V + + D+N++P +F + E+ +G I A +PD + Y I D + Sbjct: 473 VTVDVIDVNEAP-IFVPPQKRVEVPEDFGVGLEITSYTAREPDTFMEQKITYRI-WRDTA 530 Query: 733 NSFSLETRQG--SDKAELVTMVDLDYESPRKKYELVIRA--ASPPLWNDVRVEILVTDVN 788 N + G S +AEL D+D+ L+I SPP + + + DVN Sbjct: 531 NWLEINPETGAISTRAEL-DREDVDHVKNSTYTALIIATDNGSPPATGTGTLLLFLDDVN 589 Query: 789 DNAPVMK----DF-------QIIFNNYKDCFP-VGPFGRVPAYDADVTDKLQYRILSGNN 836 DN PV + DF II N D P PF + A V ++Y Sbjct: 590 DNGPVPEPRTMDFCQRNPEPHIININDPDLPPNTSPFTAELTHGASVNWTIEYN--DQER 647 Query: 837 ANLILLNETT---GSMTLSPQL--NTNVPKLATMEVSVTD 871 +LIL + T G ++ +L N N ++ T++V V D Sbjct: 648 ESLILKPKKTLELGDHKINLKLIDNQNKDQVTTLDVHVCD 687 Score = 120 bits (288), Expect = 8e-25 Identities = 111/360 (30%), Positives = 174/360 (48%), Gaps = 48/360 (13%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKN---AEVEYTIELVTA 67 I V D ND+ P F + ++AS EGA GT+V+ + ATD D N A + YTI Sbjct: 250 ITVTDQNDNKPQFTQEVFKASALEGALPGTSVMQVTATDIDDEVNTYTAAIGYTIP--AQ 307 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLVKATDQASPV 126 D + P + +F I+ +G + + LDRE YT++V+A D Sbjct: 308 DPMLPHNK-------------MFTINKETGVISVLTTGLDRESFPTYTLMVQAADLNG-- 352 Query: 127 SDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA 186 + LS+TAT + ++D NDN P+F+ TY SV E+ + N I + TDAD A Sbjct: 353 -EGLSTTATAVITVLDTNDNAPRFNPTTYVGSVPENEA---NVAITTLTVTDADDPNTPA 408 Query: 187 IR--YAIIGGNTQMQFSI--DSLS--GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR--- 237 Y ++ N + QF + D ++ G + K LD+E + Y L + A +P Sbjct: 409 WEAVYTVLNDN-EKQFIVVTDPVTNEGTLKTAKGLDFEAKQQYILYV-AVTNVAPFEVTL 466 Query: 238 -SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTM 296 ++T + +++ DVN+ AP F + V E+ +G I A + D + ++TY + Sbjct: 467 PTSTATVTVDVIDVNE-APIFVPPQKRVEVPEDFGVGLEITSYTAREPDTFMEQKITYRI 525 Query: 297 TDKDYTGNVDLPITIDPRSGWVYTSGQLDRE-----TQAKYQLLVTATDGGDPPRSATAT 351 +D T N + I+P +G + T +LDRE + Y L+ ATD G PP + T T Sbjct: 526 W-RD-TANW---LEINPETGAISTRAELDREDVDHVKNSTYTALIIATDNGSPPATGTGT 580 Score = 119 bits (286), Expect = 1e-24 Identities = 126/474 (26%), Positives = 200/474 (42%), Gaps = 38/474 (8%) Query: 267 SENVPIGYSIVRVQAYDADEGVNAELTYTMT-DKDYTGNVDLPITIDPRSGWVYTSGQLD 325 +E P S+V++++ E ++ Y++T + T V + I I+ +GW+ + LD Sbjct: 166 NEKGPFPKSLVQIKSNKEKE---TQVFYSITGQRADTPPVGVFI-IERETGWLKVTQPLD 221 Query: 326 RETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPV 385 RE AKY L A F ++ E PGT V Sbjct: 222 REQIAKYILFSHAVSSNGQAIEEPMEIVITVTDQNDNKPQFTQEVFKASALEGALPGTSV 281 Query: 386 VTLTATDADEDNRLHYEITGGNTRGRFSITSQNGR-------GLITVAQP-LDFKQERRY 437 + +TATD D++ + G + + N G+I+V LD + Y Sbjct: 282 MQVTATDIDDEVNTYTAAIGYTIPAQDPMLPHNKMFTINKETGVISVLTTGLDRESFPTY 341 Query: 438 VLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFE-DAPIGTTVLVVSAT 494 L V A D G S TA I + D N+ AP F Y SV E +A + T L V+ Sbjct: 342 TLMVQAADLNGEGLSTTATAVITVLDTNDNAPRFNPTTYVGSVPENEANVAITTLTVTDA 401 Query: 495 DSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTAR 554 D + Y++ ++ + + D V N G + T K LD E Y+L V Sbjct: 402 DDPNTPAWEAVYTVLNDNEKQFIVVTDP--VTNE--GTLKTAKGLDFEAKQQYILYVAVT 457 Query: 555 DGG---VPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVG 611 + V + T V + V+DVN+ P+F + ED VG ++ A + D Sbjct: 458 NVAPFEVTLPTSTATVTVDVIDVNE-APIFVPPQKRVEVPEDFGVGLEITSYTAREPDTF 516 Query: 612 LNGRIHYELDPKDREEGSFV-IDPASGVIRTNKALDRESV-----ATHDLKAVAIDGGTP 665 + +I Y + R+ +++ I+P +G I T LDRE V +T+ +A D G+P Sbjct: 517 MEQKITYRIW---RDTANWLEINPETGAISTRAELDREDVDHVKNSTYTALIIATDNGSP 573 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPN 719 P + T + + ++D+ND+ PV E + F P I +DPD PN Sbjct: 574 PATGTGTLLLFLDDVNDNGPVPEPRTMDFCQRNPEP-----HIININDPDLPPN 622 Score = 111 bits (266), Expect = 4e-22 Identities = 125/463 (26%), Positives = 203/463 (43%), Gaps = 48/463 (10%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 VF I+ +G L LDRE++A+Y + A S + I + + D NDN P Sbjct: 204 VFIIERETGWLKVTQPLDREQIAKYILFSHAV---SSNGQAIEEPMEIVITVTDQNDNKP 260 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGAN---SAIRYAIIGGNTQM----QFS 201 QF+++ + S E + ++ ATD D N +AI Y I + + F+ Sbjct: 261 QFTQEVFKASALE--GALPGTSVMQVTATDIDDEVNTYTAAIGYTIPAQDPMLPHNKMFT 318 Query: 202 IDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260 I+ +G +S++ T LD E +Y L+++A D S T +I + D NDNAPRF + Sbjct: 319 INKETGVISVLTTGLDRESFPTYTLMVQAADLNGEGLSTTATAVITVLDTNDNAPRFNPT 378 Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNA--ELTYTM---TDKDYTGNVDLPITIDPRS 315 + SV EN +I + DAD+ E YT+ +K + D P+T Sbjct: 379 TYVGSVPEN-EANVAITTLTVTDADDPNTPAWEAVYTVLNDNEKQFIVVTD-PVT---NE 433 Query: 316 GWVYTSGQLDRETQAKYQLLVTATDGGD-----PPRSATATXXXXXXXXXXXXXXFMPGQ 370 G + T+ LD E + +Y L V T+ P +AT T F+P Q Sbjct: 434 GTLKTAKGLDFEAKQQYILYVAVTNVAPFEVTLPTSTATVT---VDVIDVNEAPIFVPPQ 490 Query: 371 YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGGNTRGRFSITSQNGRGLITVA-- 426 VE+ ED G + + TA + D + ++ Y I +T I + G + T A Sbjct: 491 KRVEVPEDFGVGLEITSYTAREPDTFMEQKITYRI-WRDTANWLEINPETG-AISTRAEL 548 Query: 427 --QPLDFKQERRYVLTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 + +D + Y + ATD+G + T + + + D N+ PV E P T + Sbjct: 549 DREDVDHVKNSTYTALIIATDNGSPPATGTGTLLLFLDDVNDNGPVPE--PRTMDFCQRN 606 Query: 483 PIGTTVLVVSATDSDVGIN-AQITYSLSSEIS-NEAVAHHDQQ 523 P +++ D D+ N + T L+ S N + ++DQ+ Sbjct: 607 P---EPHIININDPDLPPNTSPFTAELTHGASVNWTIEYNDQE 646 >UniRef50_UPI0000E473B6 Cluster: PREDICTED: similar to cadherin; n=1; Strongylocentrotus purpuratus|Rep: PREDICTED: similar to cadherin - Strongylocentrotus purpuratus Length = 211 Score = 149 bits (360), Expect = 1e-33 Identities = 72/172 (41%), Positives = 110/172 (63%), Gaps = 12/172 (6%) Query: 886 LITEEMLLNSITVRLNDMTAEQFLSPLLGFFIDGLAAIIPCPKENIYIFSVQDDTDVTGN 945 ++T +ML +S+TV++ DM + +FL+P L FID LA IIP ++ +Y+FS++D+ + Sbjct: 12 MVTHDMLFSSVTVQVEDMQSHEFLTPKLLQFIDALAGIIPANQDLVYLFSIKDEETM--- 68 Query: 946 ILNVSFSARRPDAEVGVAGDPSPHYSPTHLRERVYLHRTTLARLATVQVLPFDDNICVHE 1005 ILN++F+A+RPD +S +L+ERVYL R+ L+ VLPF DN+C++E Sbjct: 69 ILNITFAAQRPDGSF---------FSSQYLQERVYLKRSQLSEALGATVLPFGDNLCLNE 119 Query: 1006 PCLNFEECLTVLKFGNASGFVNSDSVLFRPIYPVTSFTCQCPEGFTGVNCET 1057 C +F +C+ L F GF+ + SV+FR I+P T + C CP GFTG C T Sbjct: 120 ICSDFYQCIAPLVFWTPGGFIATTSVIFRSIHPETIYKCDCPPGFTGNYCMT 171 >UniRef50_Q4SF84 Cluster: Chromosome undetermined SCAF14607, whole genome shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome undetermined SCAF14607, whole genome shotgun sequence - Tetraodon nigroviridis (Green puffer) Length = 684 Score = 149 bits (360), Expect = 1e-33 Identities = 151/520 (29%), Positives = 231/520 (44%), Gaps = 69/520 (13%) Query: 177 TDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPS 236 TD DVG S I+Y + G F+I+ L+GD+ +K LD E+ Y L + + + Sbjct: 164 TDLDVGGKS-IKYILTGEGAGTIFAINELTGDIHAMKRLDREEKAEYTLTAQVINADTDE 222 Query: 237 RSNT-TQLLINIRDVNDNAPRFYTSLFQESVSENVPIGY---------SIVRVQAYDADE 286 ++ +I ++D+NDN P+F + + SV E +G + RV A DAD+ Sbjct: 223 PLEPPSEFIIKVQDINDNPPQFIEAPYHSSVPEMSAVGCVRALHASGTPVTRVTATDADD 282 Query: 287 ---GVNAELTYTMTD-KDYTGNVDLPITIDPRSGWVYTSGQ-LDRETQAKYQLLVTATDG 341 G +A+L Y++ + + Y +IDP S + + Q +DRE + +Y +++ A D Sbjct: 283 PVYGNSAKLVYSILEGQPY-------FSIDPNSATIKVALQGMDREMREEYLVVIQAKDM 335 Query: 342 GDPPR--SATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD--EDN 397 G S T T F YE + ED P G + A D D E++ Sbjct: 336 GGHMGGLSGTTTVTITLTDINDNPPKFSKNLYEFVIPEDLPTGKMGGKVKANDRDTGENS 395 Query: 398 RLHYEITGGNTRGRFSIT--SQNGRGLITVAQPLDFKQERRYVLTVSATD------SGGR 449 + Y I G+ +G F I SQ G++ + +PLD++ +R Y L V AT+ SGG Sbjct: 396 KSTYGIVEGDDQGVFEIVTDSQTQEGILRLKKPLDYESKRAYTLKVEATNIRSEPGSGGP 455 Query: 450 -SDTAMVQINITDANNYAPVF----------ENAPYTA---SVFEDAPIGTTVLVVSATD 495 DTA V+I + D++ PVF ENAP SV P T V T Sbjct: 456 FKDTATVKIAVEDSDE-PPVFSKPIYQLEVNENAPINTVIGSVMARDPDSTGSQVSPETS 514 Query: 496 SDVGINAQITYSLSSEISNEA--------------VAHH---DQQFVINPQTGAITTNKL 538 + + + Q+ + + E + + H ++QF IN G IT K Sbjct: 515 AILKLLGQVRWFGTQETDSPVGVLNASSQQGFRYFIDRHTDLERQFNINVDDGKITLAKP 574 Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 LDRET + +TVTA + S V I V+D NDN P F + Y + E+ G Sbjct: 575 LDRETDMWHNITVTATEVRNHSQISRAIVAIRVMDYNDNAPEFATE-YETFLCENGKPGQ 633 Query: 599 SVSQVGATDADVGLNGR-IHYELDPKDREEGSFVIDPASG 637 + + A D D + G +Y L P+ +F I G Sbjct: 634 VIQTISAVDKDDPIQGHYFNYRLAPEMLNNPNFTIKNNQG 673 Score = 118 bits (285), Expect = 2e-24 Identities = 97/324 (29%), Positives = 155/324 (47%), Gaps = 23/324 (7%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +F I+ +G + LDRE+ A YT+ + + + + L + + + D NDN P Sbjct: 185 IFAINELTGDIHAMKRLDREEKAEYTLTAQVIN--ADTDEPLEPPSEFIIKVQDINDNPP 242 Query: 149 QFSEKTYTVSVDEDISV-------TDNPVIAKIKATDAD--VGANSA-IRYAIIGGNTQM 198 QF E Y SV E +V + ++ ATDAD V NSA + Y+I+ G Q Sbjct: 243 QFIEAPYHSSVPEMSAVGCVRALHASGTPVTRVTATDADDPVYGNSAKLVYSILEG--QP 300 Query: 199 QFSIDSLSGDVSL-VKTLDYEQVRSYRLVIRAQDGGSP--SRSNTTQLLINIRDVNDNAP 255 FSID S + + ++ +D E Y +VI+A+D G S TT + I + D+NDN P Sbjct: 301 YFSIDPNSATIKVALQGMDREMREEYLVVIQAKDMGGHMGGLSGTTTVTITLTDINDNPP 360 Query: 256 RFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRS 315 +F +L++ + E++P G +V+A D D G N++ TY + + D G ++ + Sbjct: 361 KFSKNLYEFVIPEDLPTGKMGGKVKANDRDTGENSKSTYGIVEGDDQGVFEIVTDSQTQE 420 Query: 316 GWVYTSGQLDRETQAKYQLLVTATD-----GGDPPRSATATXXXXXXXXXXXXXXFMPGQ 370 G + LD E++ Y L V AT+ G P TAT P Sbjct: 421 GILRLKKPLDYESKRAYTLKVEATNIRSEPGSGGPFKDTATVKIAVEDSDEPPVFSKP-I 479 Query: 371 YEVELAEDEPPGTPVVTLTATDAD 394 Y++E+ E+ P T + ++ A D D Sbjct: 480 YQLEVNENAPINTVIGSVMARDPD 503 Score = 112 bits (269), Expect = 2e-22 Identities = 111/354 (31%), Positives = 156/354 (44%), Gaps = 35/354 (9%) Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553 TD DVG I Y L+ E + F IN TG I K LDRE + Y LT Sbjct: 164 TDLDVG-GKSIKYILTGEGAGTI-------FAINELTGDIHAMKRLDREEKAEYTLTAQV 215 Query: 554 RDGGVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVG---------TSVSQV 603 + L ++ I V D+NDN P F + Y +++ E + VG T V++V Sbjct: 216 INADTDEPLEPPSEFIIKVQDINDNPPQFIEAPYHSSVPEMSAVGCVRALHASGTPVTRV 275 Query: 604 GATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTN-KALDRESVATH--DLKAVAI 660 ATDAD + G + + F IDP S I+ + +DRE + ++A + Sbjct: 276 TATDADDPVYGNSAKLVYSILEGQPYFSIDPNSATIKVALQGMDREMREEYLVVIQAKDM 335 Query: 661 DGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNA 720 G S T V I + DIND+PP F + F I E+ P G G+++A+D D G N+ Sbjct: 336 GGHMGGLSGTTTVTITLTDINDNPPKFSKNLYEFVIPEDLPTGKMGGKVKANDRDTGENS 395 Query: 721 VVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRA--------ASP 772 Y I GDD F + T + + L LDYES ++ Y L + A + Sbjct: 396 KSTYGIVEGDDQGVFEIVTDSQTQEGILRLKKPLDYES-KRAYTLKVEATNIRSEPGSGG 454 Query: 773 PLWNDVRVEILVTDVNDNAPVMKD--FQIIFNNYKDCFPVGPFGRVPAYDADVT 824 P + V+I V D +D PV +Q+ N V G V A D D T Sbjct: 455 PFKDTATVKIAVED-SDEPPVFSKPIYQLEVNENAPINTV--IGSVMARDPDST 505 Score = 100 bits (239), Expect = 7e-19 Identities = 145/552 (26%), Positives = 224/552 (40%), Gaps = 83/552 (15%) Query: 230 QDGGSPSRSNTTQLLINIRDVNDNAPRFYT--SLFQESVSENVPIGYSIVRVQAY-DADE 286 Q G R TT L + + + + Y+ ++F+E ++ G+ Q + D D Sbjct: 112 QSAGLQHRPATTPTLQTTQTFSSSIKQLYSLITVFEELSNQG---GHYFGYCQLHTDLDV 168 Query: 287 GVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG-DPP 345 G + Y +T + G + I+ +G ++ +LDRE +A+Y L + D P Sbjct: 169 G-GKSIKYILTGEG-AGTI---FAINELTGDIHAMKRLDREEKAEYTLTAQVINADTDEP 223 Query: 346 RSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEP---------PGTPVVTLTATDADE- 395 + F+ Y + E GTPV +TATDAD+ Sbjct: 224 LEPPSEFIIKVQDINDNPPQFIEAPYHSSVPEMSAVGCVRALHASGTPVTRVTATDADDP 283 Query: 396 ----DNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGR-- 449 +L Y I G FSI N + Q +D + Y++ + A D GG Sbjct: 284 VYGNSAKLVYSILEGQPY--FSI-DPNSATIKVALQGMDREMREEYLVVIQAKDMGGHMG 340 Query: 450 --SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYS 507 S T V I +TD N+ P F Y + ED P G V A D D G N++ TY Sbjct: 341 GLSGTTTVTITLTDINDNPPKFSKNLYEFVIPEDLPTGKMGGKVKANDRDTGENSKSTYG 400 Query: 508 LSSEISNEAVAHHDQQFVINPQT--GAITTNKLLDRETMSGYLLTVTARD-----GGVPS 560 + E ++ V + V + QT G + K LD E+ Y L V A + G Sbjct: 401 IV-EGDDQGVF----EIVTDSQTQEGILRLKKPLDYESKRAYTLKVEATNIRSEPGSGGP 455 Query: 561 LSDTTDVEISVVDVND----NEPVFKQQLYTANIMEDALVGTSV--------SQVGA--- 605 DT V+I+V D ++ ++P+++ ++ N + ++G+ + SQV Sbjct: 456 FKDTATVKIAVEDSDEPPVFSKPIYQLEV-NENAPINTVIGSVMARDPDSTGSQVSPETS 514 Query: 606 ----------------TDADVG-LNGR----IHYELDPKDREEGSFVIDPASGVIRTNKA 644 TD+ VG LN Y +D E F I+ G I K Sbjct: 515 AILKLLGQVRWFGTQETDSPVGVLNASSQQGFRYFIDRHTDLERQFNINVDDGKITLAKP 574 Query: 645 LDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGT 704 LDRE+ H++ A + Q S IV I++ D ND+ P F ++ TF + EN G Sbjct: 575 LDRETDMWHNITVTATEVRNHSQISRAIVAIRVMDYNDNAPEFATEYETF-LCENGKPGQ 633 Query: 705 TIGEIRAHDPDE 716 I I A D D+ Sbjct: 634 VIQTISAVDKDD 645 >UniRef50_Q7SZW3 Cluster: Novel protein similar to zebrafish epithelial cadherin 1; n=5; Danio rerio|Rep: Novel protein similar to zebrafish epithelial cadherin 1 - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 677 Score = 148 bits (359), Expect = 2e-33 Identities = 128/466 (27%), Positives = 207/466 (44%), Gaps = 38/466 (8%) Query: 163 ISVTDN---PVIAKIKATDADVGANSAIRYAIIGGNTQMQ----FSIDSLSGDVSLVKTL 215 +SV +N P ++ +D + + Y I G F ID LSG +++ + L Sbjct: 102 VSVFENSKGPFPMRLVQIKSDSASEYQMAYKITGEGADQDPKGIFKIDRLSGWINVTQQL 161 Query: 216 DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275 D E+ SY+LV A + ++ + D NDN P F + F +V E + G Sbjct: 162 DREEKASYKLVAHATGVDVNIVEKPFEFIVTVTDQNDNKPVFTQNPFNANVPEALEKGEV 221 Query: 276 IVRVQAYDADEGVN---AELTYTMTDKDYTGNVDLPITIDPRSGWVYT-SGQLDRETQAK 331 + V A DAD+ N A+++Y + +D + I+P SG + LDRE ++ Sbjct: 222 FMTVTATDADDKENTDNADISYAIISQDPPSAKPIMFAINPVSGGISVLETGLDREQWSR 281 Query: 332 YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTAT 391 Y L++TATD S T T F + V + E++ G V L T Sbjct: 282 YTLVITATDMNGEGGSTTGTAVITVMDSNDNAPLFEQTSHTVSVPENQV-GAQVANLPVT 340 Query: 392 DADEDNRL----HYEITGGNTRGRFSITSQNGR--GLITVAQPLDFKQERRYVLTVSATD 445 D DE Y + GG+ G F++++ R G+IT +PLD+++ ++Y+L V + Sbjct: 341 DGDEPESTAWSTKYRVIGGDKGGFFNVSTGPSRLEGVITTVKPLDYEKTKQYILFVIVVN 400 Query: 446 SGG-----RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 + TA V +N+ D N P F S ED P+G+ +++ +ATD D Sbjct: 401 DDKFVGSLPTSTATVTVNVEDVNE-PPEFIPKEKFISKPEDLPVGSNLVIYTATDVDTEK 459 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS----GYLLTVTARDG 556 +ITY + + S ++ +G I +DRE+ + Y + A D Sbjct: 460 KQKITYRIDYDPSG---------WLSITDSGQIQVKTAMDRESSNVKDGKYKALILALDD 510 Query: 557 GVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 V S + T + I + DVNDN PV ++ E ALV S++ Sbjct: 511 DVESPATGTGTLVIELQDVNDNAPVINERTIKLCNRESALVLLSIT 556 Score = 127 bits (306), Expect = 5e-27 Identities = 127/430 (29%), Positives = 199/430 (46%), Gaps = 36/430 (8%) Query: 391 TDADEDNRLHYEITGGNT----RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT-- 444 +D+ + ++ Y+ITG +G F I +G I V Q LD +++ Y L AT Sbjct: 121 SDSASEYQMAYKITGEGADQDPKGIFKIDRLSG--WINVTQQLDREEKASYKLVAHATGV 178 Query: 445 DSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN--- 501 D + +TD N+ PVF P+ A+V E G + V+ATD+D N Sbjct: 179 DVNIVEKPFEFIVTVTDQNDNKPVFTQNPFNANVPEALEKGEVFMTVTATDADDKENTDN 238 Query: 502 AQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKL-LDRETMSGYLLTVTARDGGVPS 560 A I+Y++ IS + + F INP +G I+ + LDRE S Y L +TA D Sbjct: 239 ADISYAI---ISQDPPSAKPIMFAINPVSGGISVLETGLDREQWSRYTLVITATDMNGEG 295 Query: 561 LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNGRIHYEL 620 S T I+V+D NDN P+F+Q +T ++ E+ VG V+ + TD D + + Sbjct: 296 GSTTGTAVITVMDSNDNAPLFEQTSHTVSVPENQ-VGAQVANLPVTDGDEPESTAWSTKY 354 Query: 621 DPKDREEGSFV---IDPA--SGVIRTNKALDRESVATHDLKAVAIDG----GTPPQSSTV 671 ++G F P+ GVI T K LD E + L + ++ G+ P +ST Sbjct: 355 RVIGGDKGGFFNVSTGPSRLEGVITTVKPLDYEKTKQYILFVIVVNDDKFVGSLP-TSTA 413 Query: 672 IVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDD 731 V + +ED+N+ PP F E+ P+G+ + A D D + Y I D Sbjct: 414 TVTVNVEDVNE-PPEFIPKEKFISKPEDLPVGSNLVIYTATDVDTEKKQKITYRIDY-DP 471 Query: 732 SNSFSLETRQGSDKAELVTMVDLDYESPRK-KYELVIRA----ASPPLWNDVRVEILVTD 786 S S+ S + ++ T +D + + + KY+ +I A P + I + D Sbjct: 472 SGWLSITD---SGQIQVKTAMDRESSNVKDGKYKALILALDDDVESPATGTGTLVIELQD 528 Query: 787 VNDNAPVMKD 796 VNDNAPV+ + Sbjct: 529 VNDNAPVINE 538 Score = 126 bits (304), Expect = 9e-27 Identities = 132/476 (27%), Positives = 213/476 (44%), Gaps = 54/476 (11%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAE-VEYTIELVTADT 69 + V D ND+ PVF + A+V E G +T+ ATD D +N + + + +++ D Sbjct: 191 VTVTDQNDNKPVFTQNPFNANVPEALEKGEVFMTVTATDADDKENTDNADISYAIISQD- 249 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLVKATDQASPVSD 128 P A +F I+ SG + + LDRE+ +RYT+++ ATD + Sbjct: 250 --PPSAKPI----------MFAINPVSGGISVLETGLDREQWSRYTLVITATDMN---GE 294 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA-- 186 S+T T + ++D NDN P F + ++TVSV E+ +A + TD D ++A Sbjct: 295 GGSTTGTAVITVMDSNDNAPLFEQTSHTVSVPEN---QVGAQVANLPVTDGDEPESTAWS 351 Query: 187 IRYAIIGGNTQMQFSIDS----LSGDVSLVKTLDYEQVRSYRL-VIRAQD----GGSPSR 237 +Y +IGG+ F++ + L G ++ VK LDYE+ + Y L VI D G P Sbjct: 352 TKYRVIGGDKGGFFNVSTGPSRLEGVITTVKPLDYEKTKQYILFVIVVNDDKFVGSLP-- 409 Query: 238 SNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMT 297 ++T + +N+ DVN+ P F S E++P+G ++V A D D ++TY + Sbjct: 410 TSTATVTVNVEDVNE-PPEFIPKEKFISKPEDLPVGSNLVIYTATDVDTEKKQKITYRI- 467 Query: 298 DKDYTGNVDLPITIDPRSGWVYTSGQLDRET----QAKYQLLVTATDGGDPPRSATATXX 353 DY + L IT SG + +DRE+ KY+ L+ A D D AT T Sbjct: 468 --DYDPSGWLSIT---DSGQIQVKTAMDRESSNVKDGKYKALILALD-DDVESPATGTGT 521 Query: 354 XXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADED---NRLHYEITGGNTRG 410 + + ++L E + +V L+ TD D E G ++ Sbjct: 522 LVIELQDVNDNAPVINERTIKLCNRE---SALVLLSITDNDGPPFAGPFSVEPQGDTSKN 578 Query: 411 RFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYA 466 ++ G L +Q + E VL V TD G S +Q ++ D A Sbjct: 579 WSVFFNETGHYLSLKSQSRLDQGEYNVVLRV--TDREGESQENTIQASVCDCKGEA 632 Score = 120 bits (288), Expect = 8e-25 Identities = 138/524 (26%), Positives = 225/524 (42%), Gaps = 38/524 (7%) Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 SV EN G +R+ +D ++ Y +T + + ID SGW+ + QL Sbjct: 103 SVFENSK-GPFPMRLVQIKSDSASEYQMAYKITGEGADQDPKGIFKIDRLSGWINVTQQL 161 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 DRE +A Y+L+ AT F + + E G Sbjct: 162 DREEKASYKLVAHATGVDVNIVEKPFEFIVTVTDQNDNKPVFTQNPFNANVPEALEKGEV 221 Query: 385 VVTLTATDADE----DNR-LHYEITGGNTRGR----FSITSQNGRGLITVAQPLDFKQER 435 +T+TATDAD+ DN + Y I + F+I +G G+ + LD +Q Sbjct: 222 FMTVTATDADDKENTDNADISYAIISQDPPSAKPIMFAINPVSG-GISVLETGLDREQWS 280 Query: 436 RYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 RY L ++ATD G S T I + D+N+ AP+FE +T SV E+ +G V + Sbjct: 281 RYTLVITATDMNGEGGSTTGTAVITVMDSNDNAPLFEQTSHTVSVPENQ-VGAQVANLPV 339 Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553 TD D + + I + + + G ITT K LD E Y+L V Sbjct: 340 TDGDEPESTAWSTKYRV-IGGDKGGFFNVSTGPSRLEGVITTVKPLDYEKTKQYILFVIV 398 Query: 554 --RDGGVPSL-SDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610 D V SL + T V ++V DVN+ ++ + + ED VG+++ ATD D Sbjct: 399 VNDDKFVGSLPTSTATVTVNVEDVNEPPEFIPKEKFISK-PEDLPVGSNLVIYTATDVDT 457 Query: 611 GLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAI-----DGGTP 665 +I Y + D + ++ SG I+ A+DRES D K A+ D Sbjct: 458 EKKQKITYRI---DYDPSGWLSITDSGQIQVKTAMDRESSNVKDGKYKALILALDDDVES 514 Query: 666 PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYS 725 P + T + I+++D+ND+ PV + E++ + +I + ++GP +S Sbjct: 515 PATGTGTLVIELQDVNDNAPVINERTIKLCNRESALVLLSITD------NDGPPFAGPFS 568 Query: 726 IK-GGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIR 768 ++ GD S ++S+ + L + LD + +Y +V+R Sbjct: 569 VEPQGDTSKNWSVFFNETGHYLSLKSQSRLD----QGEYNVVLR 608 Score = 115 bits (276), Expect = 2e-23 Identities = 123/433 (28%), Positives = 187/433 (43%), Gaps = 42/433 (9%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +F+ID SG + LDRE+ A Y ++ AT + ++ V + D NDN P Sbjct: 145 IFKIDRLSGWINVTQQLDREEKASYKLVAHATGVDVNIVEK---PFEFIVTVTDQNDNKP 201 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA---IRYAIIGGNTQ----MQFS 201 F++ + +V E ++ V + ATDAD N+ I YAII + + F+ Sbjct: 202 VFTQNPFNANVPE--ALEKGEVFMTVTATDADDKENTDNADISYAIISQDPPSAKPIMFA 259 Query: 202 IDSLSGDVSLVKT-LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260 I+ +SG +S+++T LD EQ Y LVI A D S T +I + D NDNAP F + Sbjct: 260 INPVSGGISVLETGLDREQWSRYTLVITATDMNGEGGSTTGTAVITVMDSNDNAPLFEQT 319 Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNA--ELTYTMTDKDYTGNVDLPITIDPRSGWV 318 SV EN +G + + D DE + Y + D G ++ G + Sbjct: 320 SHTVSVPEN-QVGAQVANLPVTDGDEPESTAWSTKYRVIGGDKGGFFNVSTGPSRLEGVI 378 Query: 319 YTSGQLDRETQAKYQLLVTATD-----GGDPPRSATATXXXXXXXXXXXXXXFMPGQYEV 373 T LD E +Y L V + G P +AT T F+P + + Sbjct: 379 TTVKPLDYEKTKQYILFVIVVNDDKFVGSLPTSTATVT---VNVEDVNEPPEFIPKEKFI 435 Query: 374 ELAEDEPPGTPVVTLTATDADED--NRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDF 431 ED P G+ +V TATD D + ++ Y I + G SIT G I V +D Sbjct: 436 SKPEDLPVGSNLVIYTATDVDTEKKQKITYRI-DYDPSGWLSITDS---GQIQVKTAMDR 491 Query: 432 K----QERRYVLTVSATDSGGRS---DTAMVQINITDANNYAPVFENAPYTASVFEDAPI 484 + ++ +Y + A D S T + I + D N+ APV E A Sbjct: 492 ESSNVKDGKYKALILALDDDVESPATGTGTLVIELQDVNDNAPVINERTIKLCNRESA-- 549 Query: 485 GTTVLVVSATDSD 497 ++++S TD+D Sbjct: 550 ---LVLLSITDND 559 >UniRef50_Q90Z37 Cluster: E-cadherin; n=19; Danio rerio|Rep: E-cadherin - Danio rerio (Zebrafish) (Brachydanio rerio) Length = 864 Score = 145 bits (352), Expect = 1e-32 Identities = 129/466 (27%), Positives = 207/466 (44%), Gaps = 38/466 (8%) Query: 163 ISVTDN---PVIAKIKATDADVGANSAIRYAIIGGNTQMQ----FSIDSLSGDVSLVKTL 215 ISV++N P ++ +D + + Y I G + F+ID LSG VS+ + L Sbjct: 147 ISVSENSKGPFPMRLVQIKSDYAIETRLAYKITGEGADLDPKGIFTIDRLSGWVSVTQLL 206 Query: 216 DYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYS 275 D E+ SY+L A + +++ + D NDN P F + F +V E + G Sbjct: 207 DREKKASYKLRAHANGVDADVTEKPMDIIVTVTDQNDNKPVFTQNPFNGNVPEALEKGEV 266 Query: 276 IVRVQAYDADEGV---NAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQ-LDRETQAK 331 + V A DAD+ NA+++Y + +D I+P SG + + LDRE + Sbjct: 267 FMTVTATDADDKENTDNADISYVIISQDPPSPKPNMFAINPVSGGISVLEKGLDREQWFR 326 Query: 332 YQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTAT 391 Y L++TATD S T T F Y + E++ G V L T Sbjct: 327 YTLVITATDMNGEGLSTTGTAVITVTDSNDNAPLFEQSSYTASVPENQ-VGVEVAKLPVT 385 Query: 392 DADEDN----RLHYEITGGNTRGRFSITSQNGR--GLITVAQPLDFKQERRYVLTVSATD 445 D DE Y+I G+ G F+I++ R G+IT +PLD+++ ++Y+L+V + Sbjct: 386 DGDEPESTAWSTKYQIIAGDKGGFFNISTGPSRLEGIITTVKPLDYEKTKQYILSVIVVN 445 Query: 446 SGG-----RSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGI 500 + TA V +N+ D N P F S E+ P+G+ ++ +A D D Sbjct: 446 DDKFVGPLPTSTATVTVNVKDVNE-PPEFIPKEKFISRPENLPVGSNLIPFTAIDPDTEK 504 Query: 501 NAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS----GYLLTVTARDG 556 ITY + ++ S+ ++ +G I LDRE+ + Y + A D Sbjct: 505 KQNITYRIGNDPSD---------WLNITGSGQIQVKNALDRESSNVKDGKYKALILALDN 555 Query: 557 GVPS-LSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVS 601 V S + T + I + DVNDN PV ++ E A V S++ Sbjct: 556 DVESPATGTGTLVIELQDVNDNAPVINERTIKLCNRESAPVLLSIT 601 Score = 144 bits (350), Expect = 2e-32 Identities = 133/439 (30%), Positives = 205/439 (46%), Gaps = 37/439 (8%) Query: 396 DNRLHYEITGGNT----RGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT--DSGGR 449 + RL Y+ITG +G F+I +G ++V Q LD +++ Y L A D+ Sbjct: 171 ETRLAYKITGEGADLDPKGIFTIDRLSG--WVSVTQLLDREKKASYKLRAHANGVDADVT 228 Query: 450 SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGIN---AQITY 506 + + +TD N+ PVF P+ +V E G + V+ATD+D N A I+Y Sbjct: 229 EKPMDIIVTVTDQNDNKPVFTQNPFNGNVPEALEKGEVFMTVTATDADDKENTDNADISY 288 Query: 507 SLSSEISNEAVAHHDQQFVINPQTGAITT-NKLLDRETMSGYLLTVTARDGGVPSLSDTT 565 + IS + + F INP +G I+ K LDRE Y L +TA D LS T Sbjct: 289 VI---ISQDPPSPKPNMFAINPVSGGISVLEKGLDREQWFRYTLVITATDMNGEGLSTTG 345 Query: 566 DVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV--GLNGRIHYELDPK 623 I+V D NDN P+F+Q YTA++ E+ VG V+++ TD D Y++ Sbjct: 346 TAVITVTDSNDNAPLFEQSSYTASVPENQ-VGVEVAKLPVTDGDEPESTAWSTKYQIIAG 404 Query: 624 DREEGSFVIDPA----SGVIRTNKALDRESVATHDLKAVAIDGGT---PPQSSTVIVHIK 676 D+ G F I G+I T K LD E + L + ++ P +ST V + Sbjct: 405 DKG-GFFNISTGPSRLEGIITTVKPLDYEKTKQYILSVIVVNDDKFVGPLPTSTATVTVN 463 Query: 677 IEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFS 736 ++D+N+ PP F EN P+G+ + A DPD + Y I G D S+ + Sbjct: 464 VKDVNE-PPEFIPKEKFISRPENLPVGSNLIPFTAIDPDTEKKQNITYRI-GNDPSDWLN 521 Query: 737 LETRQGSDKAELVTMVDLDYESPRK-KYELVIRA----ASPPLWNDVRVEILVTDVNDNA 791 + GS + ++ +D + + + KY+ +I A P + I + DVNDNA Sbjct: 522 IT---GSGQIQVKNALDRESSNVKDGKYKALILALDNDVESPATGTGTLVIELQDVNDNA 578 Query: 792 PVMKDFQIIFNNYKDCFPV 810 PV+ + I N ++ PV Sbjct: 579 PVINERTIKLCN-RESAPV 596 Score = 131 bits (317), Expect = 2e-28 Identities = 128/473 (27%), Positives = 211/473 (44%), Gaps = 48/473 (10%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAE-VEYTIELVTADT 69 + V D ND+ PVF + +V E G +T+ ATD D +N + + + +++ D Sbjct: 236 VTVTDQNDNKPVFTQNPFNGNVPEALEKGEVFMTVTATDADDKENTDNADISYVIISQDP 295 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGAL-LTRASLDREKVARYTVLVKATDQASPVSD 128 +P+ ++F I+ SG + + LDRE+ RYT+++ ATD + Sbjct: 296 PSPK-------------PNMFAINPVSGGISVLEKGLDREQWFRYTLVITATDMN---GE 339 Query: 129 RLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSA-- 186 LS+T T + + D NDN P F + +YT SV E+ + +AK+ TD D ++A Sbjct: 340 GLSTTGTAVITVTDSNDNAPLFEQSSYTASVPENQVGVE---VAKLPVTDGDEPESTAWS 396 Query: 187 IRYAIIGGNTQMQFSIDS----LSGDVSLVKTLDYEQVRSYRL-VIRAQDGG--SPSRSN 239 +Y II G+ F+I + L G ++ VK LDYE+ + Y L VI D P ++ Sbjct: 397 TKYQIIAGDKGGFFNISTGPSRLEGIITTVKPLDYEKTKQYILSVIVVNDDKFVGPLPTS 456 Query: 240 TTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDK 299 T + +N++DVN+ P F S EN+P+G +++ A D D +TY + Sbjct: 457 TATVTVNVKDVNE-PPEFIPKEKFISRPENLPVGSNLIPFTAIDPDTEKKQNITYRI--- 512 Query: 300 DYTGNVDLPITIDPRSGWVYTSGQLDRET----QAKYQLLVTATDGGDPPRSATATXXXX 355 GN SG + LDRE+ KY+ L+ A D D AT T Sbjct: 513 ---GNDPSDWLNITGSGQIQVKNALDRESSNVKDGKYKALILALD-NDVESPATGTGTLV 568 Query: 356 XXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDAD-EDNRLHYEI-TGGNTRGRFS 413 + + ++L E PV+ L+ TD D +++ G+T +S Sbjct: 569 IELQDVNDNAPVINERTIKLCNRE--SAPVL-LSITDKDLPPFAGPFKVEPQGDTSKNWS 625 Query: 414 ITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYA 466 + N G +P ++ Y + + D G S ++Q ++ D A Sbjct: 626 VFF-NETGHFLNIKPQSQLEQGEYKVVLRVADREGESQENIIQASVCDCKGEA 677 Score = 124 bits (298), Expect = 5e-26 Identities = 132/475 (27%), Positives = 206/475 (43%), Gaps = 32/475 (6%) Query: 265 SVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQL 324 SVSEN G +R+ +D + L Y +T + + TID SGWV + L Sbjct: 148 SVSENSK-GPFPMRLVQIKSDYAIETRLAYKITGEGADLDPKGIFTIDRLSGWVSVTQLL 206 Query: 325 DRETQAKYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTP 384 DRE +A Y+L A F + + E G Sbjct: 207 DREKKASYKLRAHANGVDADVTEKPMDIIVTVTDQNDNKPVFTQNPFNGNVPEALEKGEV 266 Query: 385 VVTLTATDADE----DNR-LHYEITGGNTRG----RFSITSQNGRGLITVAQPLDFKQER 435 +T+TATDAD+ DN + Y I + F+I +G G+ + + LD +Q Sbjct: 267 FMTVTATDADDKENTDNADISYVIISQDPPSPKPNMFAINPVSG-GISVLEKGLDREQWF 325 Query: 436 RYVLTVSATDSGGR--SDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSA 493 RY L ++ATD G S T I +TD+N+ AP+FE + YTASV E+ +G V + Sbjct: 326 RYTLVITATDMNGEGLSTTGTAVITVTDSNDNAPLFEQSSYTASVPENQ-VGVEVAKLPV 384 Query: 494 TDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTA 553 TD D + + I+ + + + G ITT K LD E Y+L+V Sbjct: 385 TDGDEPESTAWSTKYQI-IAGDKGGFFNISTGPSRLEGIITTVKPLDYEKTKQYILSVIV 443 Query: 554 RDGGV---PSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADV 610 + P + T V ++V DVN+ ++ + + E+ VG+++ A D D Sbjct: 444 VNDDKFVGPLPTSTATVTVNVKDVNEPPEFIPKEKFISR-PENLPVGSNLIPFTAIDPDT 502 Query: 611 GLNGRIHYEL--DPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK----AVAIDGGT 664 I Y + DP D ++ SG I+ ALDRES D K +A+D Sbjct: 503 EKKQNITYRIGNDPSD-----WLNITGSGQIQVKNALDRESSNVKDGKYKALILALDNDV 557 Query: 665 P-PQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGP 718 P + T + I+++D+ND+ PV + E++P+ +I + + P GP Sbjct: 558 ESPATGTGTLVIELQDVNDNAPVINERTIKLCNRESAPVLLSITD-KDLPPFAGP 611 Score = 116 bits (280), Expect = 7e-24 Identities = 118/429 (27%), Positives = 180/429 (41%), Gaps = 32/429 (7%) Query: 89 VFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYP 148 +F ID SG + LDREK A Y + A + V+++ I V + D NDN P Sbjct: 190 IFTIDRLSGWVSVTQLLDREKKASYKLRAHANGVDADVTEK---PMDIIVTVTDQNDNKP 246 Query: 149 QFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGA---NSAIRYAIIGGNTQM----QFS 201 F++ + +V E ++ V + ATDAD N+ I Y II + F+ Sbjct: 247 VFTQNPFNGNVPE--ALEKGEVFMTVTATDADDKENTDNADISYVIISQDPPSPKPNMFA 304 Query: 202 IDSLSGDVS-LVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTS 260 I+ +SG +S L K LD EQ Y LVI A D S T +I + D NDNAP F S Sbjct: 305 INPVSGGISVLEKGLDREQWFRYTLVITATDMNGEGLSTTGTAVITVTDSNDNAPLFEQS 364 Query: 261 LFQESVSENVPIGYSIVRVQAYDADEGVNA--ELTYTMTDKDYTGNVDLPITIDPRSGWV 318 + SV EN +G + ++ D DE + Y + D G ++ G + Sbjct: 365 SYTASVPEN-QVGVEVAKLPVTDGDEPESTAWSTKYQIIAGDKGGFFNISTGPSRLEGII 423 Query: 319 YTSGQLDRETQAKY--QLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELA 376 T LD E +Y ++V D P + F+P + + Sbjct: 424 TTVKPLDYEKTKQYILSVIVVNDDKFVGPLPTSTATVTVNVKDVNEPPEFIPKEKFISRP 483 Query: 377 EDEPPGTPVVTLTATDADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFK---- 432 E+ P G+ ++ TA D D + + + GN + + G G I V LD + Sbjct: 484 ENLPVGSNLIPFTAIDPDTEKKQNITYRIGNDPSDW--LNITGSGQIQVKNALDRESSNV 541 Query: 433 QERRYVLTVSATDSGGRS---DTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVL 489 ++ +Y + A D+ S T + I + D N+ APV E AP+ Sbjct: 542 KDGKYKALILALDNDVESPATGTGTLVIELQDVNDNAPVINERTIKLCNRESAPV----- 596 Query: 490 VVSATDSDV 498 ++S TD D+ Sbjct: 597 LLSITDKDL 605 Score = 109 bits (261), Expect = 1e-21 Identities = 100/354 (28%), Positives = 148/354 (41%), Gaps = 25/354 (7%) Query: 496 SDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARD 555 SD I ++ Y ++ E A F I+ +G ++ +LLDRE + Y L A Sbjct: 166 SDYAIETRLAYKITGE---GADLDPKGIFTIDRLSGWVSVTQLLDREKKASYKLRAHANG 222 Query: 556 GGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGL--- 612 D+ ++V D NDN+PVF Q + N+ E G V ATDAD Sbjct: 223 VDADVTEKPMDIIVTVTDQNDNKPVFTQNPFNGNVPEALEKGEVFMTVTATDADDKENTD 282 Query: 613 NGRIHYEL---DPKDREEGSFVIDPASGVIRT-NKALDRESVATHDLKAVAIDGGTPPQS 668 N I Y + DP + F I+P SG I K LDRE + L A D S Sbjct: 283 NADISYVIISQDPPSPKPNMFAINPVSGGISVLEKGLDREQWFRYTLVITATDMNGEGLS 342 Query: 669 STVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAV--VHYSI 726 +T I + D ND+ P+FE T + EN +G + ++ D DE + Y I Sbjct: 343 TTGTAVITVTDSNDNAPLFEQSSYTASVPENQ-VGVEVAKLPVTDGDEPESTAWSTKYQI 401 Query: 727 KGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVI-----RAASPPLWNDVRVE 781 GD F++ T + + T+ LDYE ++ VI + P + V Sbjct: 402 IAGDKGGFFNISTGPSRLEGIITTVKPLDYEKTKQYILSVIVVNDDKFVGPLPTSTATVT 461 Query: 782 ILVTDVNDNAPVMKDFQIIFNNYKDCFPVG----PFGRVPAYDADVTDKLQYRI 831 + V DVN+ + + I + + PVG PF + D + + YRI Sbjct: 462 VNVKDVNEPPEFIPKEKFI--SRPENLPVGSNLIPFTAIDP-DTEKKQNITYRI 512 >UniRef50_Q7PQL1 Cluster: ENSANGP00000011254; n=2; Culicidae|Rep: ENSANGP00000011254 - Anopheles gambiae str. PEST Length = 1821 Score = 144 bits (350), Expect = 2e-32 Identities = 166/570 (29%), Positives = 253/570 (44%), Gaps = 87/570 (15%) Query: 370 QYEVELAEDEPPGTPVVTLTATDAD--EDNRLHYEITG------GNTRGRFSITSQNGRG 421 Q + L E+ G + LTA D D +++++ YE+ G G F I NG Sbjct: 1097 QLKFALPENVEVGKVIFKLTANDDDFEKNSKVFYEVVGQTELNSGERVSYFRIDRNNGE- 1155 Query: 422 LITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFED 481 + VA L E L ++A D GG SD VQ + D N+ APVFE YT +V E Sbjct: 1156 -LRVANRLP--PETDVKLNITAKDVGGLSDMLQVQFRVYDVNDNAPVFEKQWYTFNVDEG 1212 Query: 482 A-PI-GTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLL 539 + PI G + V A D D G+N +TY L ++ + F I+P G I + + Sbjct: 1213 SYPITGKKIGQVRANDEDTGMNGNVTYMLITDGDQKI------PFSISPLDGTIRVSGEI 1266 Query: 540 DRETMSGYLLTVTARDGGVP-SLSDTTDVEISVVDVNDNEPVF--------------KQQ 584 DRE ++ Y V A D LS DVE+ V+D NDN P F + Sbjct: 1267 DREMIASYRFRVLASDNNFDLKLSAMVDVEVIVMDRNDNNPEFTAYDDLRSDRNNIKRLP 1326 Query: 585 LYTANIMEDALVGTSVSQVGATDADVGLNGR--IHYELDPKDREEGSFVIDPASGVIRT- 641 +Y A + +A VGT V QV A D+D NG + Y L + + F IDP GV+ T Sbjct: 1327 VYVAYLDVNAKVGTFVKQVMARDSDFRENGNGLVIYSLTGQS-DVLQFSIDPKDGVVTTA 1385 Query: 642 -----NKALDRESVATHDLKAVAIDGGTPPQSSTVIVHIKIE-------DINDSPPVFES 689 ++A R++ ++ VA D GTPP+SS ++ + ++ + + PP+F Sbjct: 1386 SKFTPSEAGTRKTYEHLNVTVVASDFGTPPRSSMALLIVNLQGDTLQQHPVEERPPLFPY 1445 Query: 690 DCLTFYISENSP-----IGTTIGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGS- 743 + EN P + T+ + A+DP + I G + F ++ R GS Sbjct: 1446 KYYEIELRENDPAPRIVLNVTLSKRYANDP-------FRWEIVGDTFDDQFRIDERNGSL 1498 Query: 744 ------DKAE------LVTMVDLDYES---PRKKYEL--VIRAASPPLW-NDVRVEILVT 785 D+ E + + + E+ P Y L ++ S L+ N+V + I V Sbjct: 1499 WLLRPLDREERDSYDVRIRVQKIKRETRNIPSVLYALENPVKRKSHRLFDNEVEIMIKVV 1558 Query: 786 DVNDNAPVMKD-FQIIFNNYKDCFPVG-PFGRVPAYDADV--TDKLQYRILSGNNANLIL 841 DVNDNAPV +D + I + D G +V A D D +++Y +L+ L Sbjct: 1559 DVNDNAPVFRDNYGPIISVVPDTANYGYAVMKVEATDDDAGSNGEVRYTLLN-EPPRLFA 1617 Query: 842 LNETTGSMTLSPQLNTNVPKLATMEVSVTD 871 ++ TG + L L + K+ +V TD Sbjct: 1618 IDSLTGQIRLLNSLASFKEKVFGFDVKATD 1647 Score = 140 bits (340), Expect = 4e-31 Identities = 159/650 (24%), Positives = 274/650 (42%), Gaps = 51/650 (7%) Query: 106 DREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISV 165 D + + +++V T S D SS TI V I D NDN P+F Y V++DE + Sbjct: 83 DPQSILKFSVFCSGTSATSAKQDN-SSFFTITVYIEDINDNDPEFINLPYVVTLDESTPI 141 Query: 166 TDNPVIAKIKATDADV--GANSAIRYAIIGGNTQ---MQFSID-SLSGDVSLVKTLDYEQ 219 + V +IKA D D NS + YA+ + + F ++ S + L + LDY+ Sbjct: 142 -ETVVFNRIKAIDRDKPNTPNSDLEYALAAKHMKSGDFPFRLEGSQRPSLVLQRALDYDA 200 Query: 220 -VRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIG----- 273 RS + I A D G+P R+ + +N+RDV+D P F + ++ + E+ P+ Sbjct: 201 GWRSMSVQIVASDRGNPPRTANATIRVNLRDVDDLPPIFTRAQYRTRIKESFPLTGKPIH 260 Query: 274 ---YSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQA 330 Y + A+D D +N L Y + GN I P +G ++ ++D ++++ Sbjct: 261 IPLYIEPPIMAFDQD-SLNETLVYGIV----AGNERQLFWISPETGVLFLQKEIDLDSES 315 Query: 331 ----KYQLLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVV 386 + L + A DP +SA A F Y + + E+ P G ++ Sbjct: 316 LPDNTFTLQIEAQQINDPTKSAFARVDIEVIDLNDNVPEFEVDLYNISIIENLPKGFSIL 375 Query: 387 TLTATDAD--EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSAT 444 + A D D E+ +Y + +G F I +G ++ LD +Q + V A Sbjct: 376 QVNAIDRDQGENAEFYYYLMDEEPKGAFMIDHGSGWIVVRDETFLDKEQRSSLKMNVHAV 435 Query: 445 DSGGRSDTA------MVQINITDANNYAPVFENAP-YTASVFEDAPIGTTVLVVSATDSD 497 + + D + V+I + D N+ P FE Y +A IG+ V + A D D Sbjct: 436 ERVEQYDRSRNYGKVQVEITLLDTNDNTPEFEQGTLYEFKTHCNASIGSKVGQIRALDPD 495 Query: 498 VGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGG 557 N +I YS+ + N + F+++P TG I ++ L T V ARD Sbjct: 496 DLGNGKIQYSIKNVRPNLVI-----PFLLDPDTGDIRVSEAL---TYGKIAFFVEARDQP 547 Query: 558 V-PSLS--DTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGATDADVGLNG 614 PS S + V I +V + + F Y + DA +G+SV Q+ T D+ + Sbjct: 548 QNPSESRFNVALVTIDIVCQSIEDIEFIGAPYEFWVGADAAIGSSVGQI-RTTFDMVSDE 606 Query: 615 RIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGTPPQSSTVIVH 674 I ++L E F I+ SG++ +++++ ++ + V P + + Sbjct: 607 EIFFDLLHSYPEGVPFAIEERSGIVTVIESMEKFDRRCYEFETVV--SYLPDSAGKNVEQ 664 Query: 675 IKIEDINDSPPVFESDCLTFYISENSPI--GTTIGEIRAHDPDEGPNAVV 722 + E N + ++ I N + GT I + PN ++ Sbjct: 665 LTPEAYNSLEKIIVTNVTIHVIKHNFMLLRGTNATPIEFRVKENKPNTMI 714 Score = 137 bits (331), Expect = 5e-30 Identities = 159/609 (26%), Positives = 249/609 (40%), Gaps = 92/609 (15%) Query: 22 VFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADTLNPEDAXXXXXX 81 V + Q + ++ E G + L A D D KN++V Y E+V LN + Sbjct: 1092 VAKKSQLKFALPENVEVGKVIFKLTANDDDFEKNSKVFY--EVVGQTELNSGERVSY--- 1146 Query: 82 XXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDRLSSTATIHVNII 141 FRID +G L L E + + K +SD L + + Sbjct: 1147 --------FRIDRNNGELRVANRLPPETDVKLNITAK---DVGGLSDMLQ----VQFRVY 1191 Query: 142 DDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRYAII-GGNTQMQF 200 D NDN P F ++ YT +VDE I +++A D D G N + Y +I G+ ++ F Sbjct: 1192 DVNDNAPVFEKQWYTFNVDEGSYPITGKKIGQVRANDEDTGMNGNVTYMLITDGDQKIPF 1251 Query: 201 SIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR-SNTTQLLINIRDVNDNAPRF-- 257 SI L G + + +D E + SYR + A D + S + + + D NDN P F Sbjct: 1252 SISPLDGTIRVSGEIDREMIASYRFRVLASDNNFDLKLSAMVDVEVIVMDRNDNNPEFTA 1311 Query: 258 YTSL------------FQESVSENVPIGYSIVRVQAYDAD--EGVNAELTYTMTDKDYTG 303 Y L + + N +G + +V A D+D E N + Y++T + Sbjct: 1312 YDDLRSDRNNIKRLPVYVAYLDVNAKVGTFVKQVMARDSDFRENGNGLVIYSLTGQSDV- 1370 Query: 304 NVDLPITIDPRSGWVYTSGQL------DRETQAKYQLLVTATDGGDPPRSATATXXXXXX 357 L +IDP+ G V T+ + R+T + V A+D G PPRS+ A Sbjct: 1371 ---LQFSIDPKDGVVTTASKFTPSEAGTRKTYEHLNVTVVASDFGTPPRSSMALLIVNLQ 1427 Query: 358 XXXXXXX-------XFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYEITGGNTRG 410 F YE+EL E++P V+ +T + ++ +EI G Sbjct: 1428 GDTLQQHPVEERPPLFPYKYYEIELRENDPAPRIVLNVTLSKRYANDPFRWEIVGDTFDD 1487 Query: 411 RFSITSQNGRGLITVAQPLD---------------FKQERR------YVLTVSATDSGGR 449 +F I +NG + + +PLD K+E R Y L R Sbjct: 1488 QFRIDERNGS--LWLLRPLDREERDSYDVRIRVQKIKRETRNIPSVLYALENPVKRKSHR 1545 Query: 450 --SDTAMVQINITDANNYAPVFEN--APYTASVFEDAPIGTTVLVVSATDSDVGINAQIT 505 + + I + D N+ APVF + P + V + A G V+ V ATD D G N ++ Sbjct: 1546 LFDNEVEIMIKVVDVNDNAPVFRDNYGPIISVVPDTANYGYAVMKVEATDDDAGSNGEVR 1605 Query: 506 YSLSSEISNEAVAHHDQQFVINPQTGAI-TTNKLLD-RETMSGYLLTVTARDGGVPSLSD 563 Y+L +E + F I+ TG I N L +E + G+ + T R+G S Sbjct: 1606 YTLLNE--------PPRLFAIDSLTGQIRLLNSLASFKEKVFGFDVKATDREGADDGKST 1657 Query: 564 TTDVEISVV 572 +V + V+ Sbjct: 1658 IANVFVYVL 1666 Score = 133 bits (322), Expect = 6e-29 Identities = 114/379 (30%), Positives = 184/379 (48%), Gaps = 24/379 (6%) Query: 371 YEVELAEDEPPGTPVVT-LTATDADEDNR----LHYEITGGNTR-GRFSITSQNG-RGLI 423 Y V L E P T V + A D D+ N L Y + + + G F + R + Sbjct: 131 YVVTLDESTPIETVVFNRIKAIDRDKPNTPNSDLEYALAAKHMKSGDFPFRLEGSQRPSL 190 Query: 424 TVAQPLDFKQERRYV-LTVSATDSGG--RSDTAMVQINITDANNYAPVFENAPYTASVFE 480 + + LD+ R + + + A+D G R+ A +++N+ D ++ P+F A Y + E Sbjct: 191 VLQRALDYDAGWRSMSVQIVASDRGNPPRTANATIRVNLRDVDDLPPIFTRAQYRTRIKE 250 Query: 481 DAPIGTTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQ-FVINPQTGAITTNKLL 539 P+ + + + I A SL+ + VA +++Q F I+P+TG + K + Sbjct: 251 SFPLTGKPIHIPLY-IEPPIMAFDQDSLNETLVYGIVAGNERQLFWISPETGVLFLQKEI 309 Query: 540 DRETMS----GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDAL 595 D ++ S + L + A+ P+ S V+I V+D+NDN P F+ LY +I+E+ Sbjct: 310 DLDSESLPDNTFTLQIEAQQINDPTKSAFARVDIEVIDLNDNVPEFEVDLYNISIIENLP 369 Query: 596 VGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASG--VIRTNKALDRESVATH 653 G S+ QV A D D G N +Y L + +G+F+ID SG V+R LD+E ++ Sbjct: 370 KGFSILQVNAIDRDQGENAEFYYYL-MDEEPKGAFMIDHGSGWIVVRDETFLDKEQRSSL 428 Query: 654 DLKAVAIDGGTPPQSS----TVIVHIKIEDINDSPPVFESDCL-TFYISENSPIGTTIGE 708 + A++ S V V I + D ND+ P FE L F N+ IG+ +G+ Sbjct: 429 KMNVHAVERVEQYDRSRNYGKVQVEITLLDTNDNTPEFEQGTLYEFKTHCNASIGSKVGQ 488 Query: 709 IRAHDPDEGPNAVVHYSIK 727 IRA DPD+ N + YSIK Sbjct: 489 IRALDPDDLGNGKIQYSIK 507 Score = 120 bits (289), Expect = 6e-25 Identities = 134/510 (26%), Positives = 221/510 (43%), Gaps = 50/510 (9%) Query: 11 INVLDCNDHSPVFEMQQYEASVREGASSGTTVLT-LKATDQDIGK--NAEVEYTIELVTA 67 + + D ND+ P F Y ++ E T V +KA D+D N+++EY + A Sbjct: 114 VYIEDINDNDPEFINLPYVVTLDESTPIETVVFNRIKAIDRDKPNTPNSDLEYAL---AA 170 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDG-RSGALLTRASLDREKVAR-YTVLVKATDQASP 125 + D FR++G + +L+ + +LD + R +V + A+D+ +P Sbjct: 171 KHMKSGDFP-------------FRLEGSQRPSLVLQRALDYDAGWRSMSVQIVASDRGNP 217 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAK------IKATDA 179 ++ ATI VN+ D +D P F+ Y + E +T P+ I A D Sbjct: 218 PR---TANATIRVNLRDVDDLPPIFTRAQYRTRIKESFPLTGKPIHIPLYIEPPIMAFDQ 274 Query: 180 DVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV----RSYRLVIRAQDGGSP 235 D N + Y I+ GN + F I +G + L K +D + ++ L I AQ P Sbjct: 275 D-SLNETLVYGIVAGNERQLFWISPETGVLFLQKEIDLDSESLPDNTFTLQIEAQQINDP 333 Query: 236 SRSNTTQLLINIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYT 295 ++S ++ I + D+NDN P F L+ S+ EN+P G+SI++V A D D+G NAE Y Sbjct: 334 TKSAFARVDIEVIDLNDNVPEFEVDLYNISIIENLPKGFSILQVNAIDRDQGENAEFYYY 393 Query: 296 MTDKDYTGNVDLPITIDPRSGWVYTSGQ--LDRETQAKYQLLVTATDGGDP-PRS---AT 349 + D++ G ID SGW+ + LD+E ++ ++ V A + + RS Sbjct: 394 LMDEEPKG----AFMIDHGSGWIVVRDETFLDKEQRSSLKMNVHAVERVEQYDRSRNYGK 449 Query: 350 ATXXXXXXXXXXXXXXFMPGQ-YEVELAEDEPPGTPVVTLTATDADE--DNRLHYEITGG 406 F G YE + + G+ V + A D D+ + ++ Y I Sbjct: 450 VQVEITLLDTNDNTPEFEQGTLYEFKTHCNASIGSKVGQIRALDPDDLGNGKIQYSIKNV 509 Query: 407 NTRGRFSITSQNGRGLITVAQPLDFKQERRYV--LTVSATDSGGRSDTAMVQINITDANN 464 G I V++ L + + +V S R + A+V I+I + Sbjct: 510 RPNLVIPFLLDPDTGDIRVSEALTYGKIAFFVEARDQPQNPSESRFNVALVTIDIVCQSI 569 Query: 465 YAPVFENAPYTASVFEDAPIGTTVLVVSAT 494 F APY V DA IG++V + T Sbjct: 570 EDIEFIGAPYEFWVGADAAIGSSVGQIRTT 599 Score = 116 bits (279), Expect = 9e-24 Identities = 155/576 (26%), Positives = 243/576 (42%), Gaps = 89/576 (15%) Query: 170 VIAKIKATDADVGANSAIRYAIIG------GNTQMQFSIDSLSGDVSLVKTLDYEQVRSY 223 VI K+ A D D NS + Y ++G G F ID +G++ + L E Sbjct: 1111 VIFKLTANDDDFEKNSKVFYEVVGQTELNSGERVSYFRIDRNNGELRVANRLPPET--DV 1168 Query: 224 RLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQESVSE-NVPI-GYSIVRVQA 281 +L I A+D G S+ Q+ + DVNDNAP F + +V E + PI G I +V+A Sbjct: 1169 KLNITAKDVGG--LSDMLQVQFRVYDVNDNAPVFEKQWYTFNVDEGSYPITGKKIGQVRA 1226 Query: 282 YDADEGVNAELTYTM-TDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATD 340 D D G+N +TY + TD G+ +P +I P G + SG++DRE A Y+ V A+D Sbjct: 1227 NDEDTGMNGNVTYMLITD----GDQKIPFSISPLDGTIRVSGEIDREMIASYRFRVLASD 1282 Query: 341 GG-DPPRSATATXXXXXXXXXXXXXXFMPGQ--------------YEVELAEDEPPGTPV 385 D SA F Y L + GT V Sbjct: 1283 NNFDLKLSAMVDVEVIVMDRNDNNPEFTAYDDLRSDRNNIKRLPVYVAYLDVNAKVGTFV 1342 Query: 386 VTLTATDAD----EDNRLHYEITGGNTRGRFSITSQNGRGLITVAQ---PLDFKQERRYV 438 + A D+D + + Y +TG + +FSI ++G ++T A P + + Y Sbjct: 1343 KQVMARDSDFRENGNGLVIYSLTGQSDVLQFSIDPKDG--VVTTASKFTPSEAGTRKTYE 1400 Query: 439 ---LTVSATDSGG--RSDTAMVQINIT-DANNYAPVFENAPYTASVFEDAPIGTTVLVVS 492 +TV A+D G RS A++ +N+ D PV E P + + + Sbjct: 1401 HLNVTVVASDFGTPPRSSMALLIVNLQGDTLQQHPVEERPPLFPYKYYE---------IE 1451 Query: 493 ATDSDVGINAQITYSLSSEISNEAVAHH------DQQFVINPQTGAITTNKLLDRETMSG 546 ++D + +LS +N+ D QF I+ + G++ + LDRE Sbjct: 1452 LRENDPAPRIVLNVTLSKRYANDPFRWEIVGDTFDDQFRIDERNGSLWLLRPLDREERDS 1511 Query: 547 YLLTVTARD-----GGVPSL----------------SDTTDVEISVVDVNDNEPVFKQQL 585 Y + + + +PS+ + ++ I VVDVNDN PVF+ Sbjct: 1512 YDVRIRVQKIKRETRNIPSVLYALENPVKRKSHRLFDNEVEIMIKVVDVNDNAPVFRDNY 1571 Query: 586 --YTANIMEDALVGTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNK 643 + + + A G +V +V ATD D G NG + Y L + F ID +G IR Sbjct: 1572 GPIISVVPDTANYGYAVMKVEATDDDAGSNGEVRYTL--LNEPPRLFAIDSLTGQIRLLN 1629 Query: 644 ALD--RESVATHDLKAVAIDGGTPPQSSTVIVHIKI 677 +L +E V D+KA +G +S+ V + + Sbjct: 1630 SLASFKEKVFGFDVKATDREGADDGKSTIANVFVYV 1665 Score = 109 bits (263), Expect = 8e-22 Identities = 134/520 (25%), Positives = 218/520 (41%), Gaps = 44/520 (8%) Query: 373 VELAEDEPPGTPVVTLTATDADE------DNRLHYE---ITGGNTRGRFSITSQNGRGLI 423 + L ED P G +V+L A + +N YE + N+ I +++ GL+ Sbjct: 20 LRLKEDFPVGGEIVSLYAYPRNSILIPRTENSSDYEYFKLKEINSTVVSVILNRSLDGLV 79 Query: 424 TVAQPLDFKQERRYVLTVSATDSG-GRSDTAMVQINITDANNYAPVFENAPYTASVFEDA 482 P + + SAT + S + + I D N+ P F N PY ++ E Sbjct: 80 DSDDPQSILKFSVFCSGTSATSAKQDNSSFFTITVYIEDINDNDPEFINLPYVVTLDEST 139 Query: 483 PIGTTVLV-VSATDSDVGI--NAQITYSLSSEISNEAVAHHDQQFVIN-PQTGAITTNKL 538 PI T V + A D D N+ + Y+L+++ D F + Q ++ + Sbjct: 140 PIETVVFNRIKAIDRDKPNTPNSDLEYALAAKHMKSG----DFPFRLEGSQRPSLVLQRA 195 Query: 539 LDRET-MSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMED-ALV 596 LD + + + A D G P + + +++ DV+D P+F + Y I E L Sbjct: 196 LDYDAGWRSMSVQIVASDRGNPPRTANATIRVNLRDVDDLPPIFTRAQYRTRIKESFPLT 255 Query: 597 GTSVS-------QVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRES 649 G + + A D D LN + Y + E F I P +GV+ K +D +S Sbjct: 256 GKPIHIPLYIEPPIMAFDQD-SLNETLVYGI-VAGNERQLFWISPETGVLFLQKEIDLDS 313 Query: 650 VATHD----LKAVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENSPIGTT 705 + D L+ A P +S+ V I++ D+ND+ P FE D I EN P G + Sbjct: 314 ESLPDNTFTLQIEAQQINDPTKSAFARVDIEVIDLNDNVPEFEVDLYNISIIENLPKGFS 373 Query: 706 IGEIRAHDPDEGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRK---- 761 I ++ A D D+G NA +Y + + +F ++ G T +D + S K Sbjct: 374 ILQVNAIDRDQGENAEFYYYLMDEEPKGAFMIDHGSGWIVVRDETFLDKEQRSSLKMNVH 433 Query: 762 KYELVIRAASPPLWNDVRVEILVTDVNDNAPVMKDFQII-FNNYKDCFPVGPFGRVPAYD 820 E V + + V+VEI + D NDN P + + F + + G++ A D Sbjct: 434 AVERVEQYDRSRNYGKVQVEITLLDTNDNTPEFEQGTLYEFKTHCNASIGSKVGQIRALD 493 Query: 821 AD--VTDKLQYRILSGNNANLI---LLNETTGSMTLSPQL 855 D K+QY I NL+ LL+ TG + +S L Sbjct: 494 PDDLGNGKIQYSI-KNVRPNLVIPFLLDPDTGDIRVSEAL 532 Score = 95.5 bits (227), Expect = 2e-17 Identities = 104/440 (23%), Positives = 182/440 (41%), Gaps = 35/440 (7%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 ++N+ D +D P+F QY ++E + T + I +E I D+ Sbjct: 226 RVNLRDVDDLPPIFTRAQYRTRIKE---------SFPLTGKPIHIPLYIEPPIMAFDQDS 276 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 LN + +F I +G L + +D + + +A ++D Sbjct: 277 LN---ETLVYGIVAGNERQLFWISPETGVLFLQKEIDLDSESLPDNTFTLQIEAQQINDP 333 Query: 130 LSST-ATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIR 188 S A + + +ID NDN P+F Y +S+ E++ + I ++ A D D G N+ Sbjct: 334 TKSAFARVDIEVIDLNDNVPEFEVDLYNISIIENLPKGFS--ILQVNAIDRDQGENAEFY 391 Query: 189 YAIIGGNTQMQFSIDSLSGDVSL--VKTLDYEQVRSYRL----VIRAQDGGSPSRSNTTQ 242 Y ++ + F ID SG + + LD EQ S ++ V R + Q Sbjct: 392 YYLMDEEPKGAFMIDHGSGWIVVRDETFLDKEQRSSLKMNVHAVERVEQYDRSRNYGKVQ 451 Query: 243 LLINIRDVNDNAPRF-YTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDY 301 + I + D NDN P F +L++ N IG + +++A D D+ N ++ Y++ K+ Sbjct: 452 VEITLLDTNDNTPEFEQGTLYEFKTHCNASIGSKVGQIRALDPDDLGNGKIQYSI--KNV 509 Query: 302 TGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPP---RSATATXXXXXXX 358 N+ +P +DP +G + S L T K V A D P R A Sbjct: 510 RPNLVIPFLLDPDTGDIRVSEAL---TYGKIAFFVEARDQPQNPSESRFNVALVTIDIVC 566 Query: 359 XXXXXXXFMPGQYEVELAEDEPPGTPVVTLTAT-DADEDNRLHYEITGGNTRG-RFSITS 416 F+ YE + D G+ V + T D D + +++ G F+I Sbjct: 567 QSIEDIEFIGAPYEFWVGADAAIGSSVGQIRTTFDMVSDEEIFFDLLHSYPEGVPFAIEE 626 Query: 417 QNGRGLITVAQPLDFKQERR 436 ++ G++TV + ++ K +RR Sbjct: 627 RS--GIVTVIESME-KFDRR 643 Score = 83.0 bits (196), Expect = 1e-13 Identities = 88/356 (24%), Positives = 150/356 (42%), Gaps = 55/356 (15%) Query: 10 QINVLDCNDHSPVFEMQQYEASVREGA--SSGTTVLTLKATDQDIGKNAEVEYTIELVTA 67 Q V D ND++PVFE Q Y +V EG+ +G + ++A D+D G N V Y + + Sbjct: 1187 QFRVYDVNDNAPVFEKQWYTFNVDEGSYPITGKKIGQVRANDEDTGMNGNVTYML-ITDG 1245 Query: 68 DTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVS 127 D P F I G + +DRE +A Y V A+D + Sbjct: 1246 DQKIP-----------------FSISPLDGTIRVSGEIDREMIASYRFRVLASDNNFDL- 1287 Query: 128 DRLSSTATIHVNIIDDNDNYPQFSE-----------KTYTVSVDE-DISVTDNPVIAKIK 175 +LS+ + V ++D NDN P+F+ K V V D++ + ++ Sbjct: 1288 -KLSAMVDVEVIVMDRNDNNPEFTAYDDLRSDRNNIKRLPVYVAYLDVNAKVGTFVKQVM 1346 Query: 176 ATDADV--GANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQV---RSY---RLVI 227 A D+D N + Y++ G + +QFSID G V+ + ++Y + + Sbjct: 1347 ARDSDFRENGNGLVIYSLTGQSDVLQFSIDPKDGVVTTASKFTPSEAGTRKTYEHLNVTV 1406 Query: 228 RAQDGGSPSRSNTTQLLINIR-------DVNDNAPRFYTSLFQESVSENVPIGYSIVRVQ 280 A D G+P RS+ L++N++ V + P F ++ + EN P ++ V Sbjct: 1407 VASDFGTPPRSSMALLIVNLQGDTLQQHPVEERPPLFPYKYYEIELRENDPAPRIVLNVT 1466 Query: 281 AYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLV 336 + N + + + D ID R+G ++ LDRE + Y + + Sbjct: 1467 L--SKRYANDPFRWEIVGDTF----DDQFRIDERNGSLWLLRPLDREERDSYDVRI 1516 Score = 72.5 bits (170), Expect = 2e-10 Identities = 98/380 (25%), Positives = 157/380 (41%), Gaps = 55/380 (14%) Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMVQINITDANNYAPVFENAPYTASVFEDAPIGTTV 488 LD ++ L + ATD ++I I D N+ APVFE ++F + Sbjct: 967 LDREEIESLTLKMMATDRDNLMSEVELKILILDVNDCAPVFERI----AIFRKS---RCE 1019 Query: 489 LVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRE--TMSG 546 ++ + +D ++ +I + E + + + + G++ N+ DRE TM Sbjct: 1020 MIENTSDLELMYLDEIETEVLPEFLDAGLMEMNSRV----SYGSVMVNRTADREHLTMRR 1075 Query: 547 YLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGTSVSQVGAT 606 L R G N K QL A + E+ VG + ++ A Sbjct: 1076 KLYKQKVRQRGR----------------NTRAVAKKSQLKFA-LPENVEVGKVIFKLTAN 1118 Query: 607 DADVGLNGRIHYEL----DPKDREEGS-FVIDPASGVIRTNKALDRESVATHDLKAVAID 661 D D N ++ YE+ + E S F ID +G +R L E+ ++ A + Sbjct: 1119 DDDFEKNSKVFYEVVGQTELNSGERVSYFRIDRNNGELRVANRLPPETDVKLNITAKDVG 1178 Query: 662 GGTPPQSSTVIVHIKIEDINDSPPVFESDCLTFYISENS-PI-GTTIGEIRAHDPDEGPN 719 G S + V ++ D+ND+ PVFE TF + E S PI G IG++RA+D D G N Sbjct: 1179 G----LSDMLQVQFRVYDVNDNAPVFEKQWYTFNVDEGSYPITGKKIGQVRANDEDTGMN 1234 Query: 720 AVVHYS-IKGGDDSNSFSLETRQGSDKA------ELVTMVDLDYESPRKKYELVIRAASP 772 V Y I GD FS+ G+ + E++ + ++L + A Sbjct: 1235 GNVTYMLITDGDQKIPFSISPLDGTIRVSGEIDREMIASYRFRVLASDNNFDLKLSAM-- 1292 Query: 773 PLWNDVRVEILVTDVNDNAP 792 V VE++V D NDN P Sbjct: 1293 -----VDVEVIVMDRNDNNP 1307 Score = 52.4 bits (120), Expect = 2e-04 Identities = 78/358 (21%), Positives = 148/358 (41%), Gaps = 35/358 (9%) Query: 539 LDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTANIMEDALVGT 598 LDRE + L + A D +L +++I ++DVND PVF++ + + T Sbjct: 967 LDREEIESLTLKMMATDRD--NLMSEVELKILILDVNDCAPVFERIAIFRKSRCEMIENT 1024 Query: 599 SVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDP--ASGVIRTNKALDRESVATHDLK 656 S D ++ I E+ P+ + G ++ + G + N+ DRE + Sbjct: 1025 S-------DLELMYLDEIETEVLPEFLDAGLMEMNSRVSYGSVMVNRTADREHLTMR--- 1074 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDIN-DSPPVFESDCLTFYISENSPIGTTIGEIRAHDPD 715 + K+ ++ V + L F + EN +G I ++ A+D D Sbjct: 1075 -------------RKLYKQKVRQRGRNTRAVAKKSQLKFALPENVEVGKVIFKLTANDDD 1121 Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW 775 N+ V Y + G + NS + D+ V + P +L I A Sbjct: 1122 FEKNSKVFYEVVGQTELNSGERVSYFRIDRNNGELRV-ANRLPPETDVKLNITAKDVGGL 1180 Query: 776 NDV-RVEILVTDVNDNAPVMKDFQIIFNNYKDCFPV--GPFGRVPAYDAD--VTDKLQYR 830 +D+ +V+ V DVNDNAPV + FN + +P+ G+V A D D + + Y Sbjct: 1181 SDMLQVQFRVYDVNDNAPVFEKQWYTFNVDEGSYPITGKKIGQVRANDEDTGMNGNVTYM 1240 Query: 831 ILSGNNANL-ILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887 +++ + + ++ G++ +S +++ + V +D ++K + V +I Sbjct: 1241 LITDGDQKIPFSISPLDGTIRVSGEIDREMIASYRFRVLASDNNFDLKLSAMVDVEVI 1298 Score = 48.0 bits (109), Expect = 0.004 Identities = 50/219 (22%), Positives = 103/219 (47%), Gaps = 25/219 (11%) Query: 7 IHQQINVLDCNDHSPVFEMQQ-YEASVREGASSGTTVLTLKATDQDIGKNAEVEYTIELV 65 + +I +LD ND++P FE YE AS G+ V ++A D D N +++Y+I+ V Sbjct: 450 VQVEITLLDTNDNTPEFEQGTLYEFKTHCNASIGSKVGQIRALDPDDLGNGKIQYSIKNV 509 Query: 66 TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125 + + P F +D +G + +L K+A + V+A DQ Sbjct: 510 RPNLVIP-----------------FLLDPDTGDIRVSEALTYGKIAFF---VEARDQPQN 549 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANS 185 S+ + A + ++I+ + +F Y V D ++ + + +I+ T D+ ++ Sbjct: 550 PSESRFNVALVTIDIVCQSIEDIEFIGAPYEFWVGADAAIGSS--VGQIRTT-FDMVSDE 606 Query: 186 AIRYAIIGGNTQ-MQFSIDSLSGDVSLVKTLDYEQVRSY 223 I + ++ + + F+I+ SG V+++++++ R Y Sbjct: 607 EIFFDLLHSYPEGVPFAIEERSGIVTVIESMEKFDRRCY 645 Score = 42.7 bits (96), Expect = 0.14 Identities = 29/67 (43%), Positives = 35/67 (52%), Gaps = 6/67 (8%) Query: 673 VHIKIEDINDSPPVFESDCLTFYISENSPIGTTI---GEIRAHDPD-EGPNAVVHYSIKG 728 V I +ED ND+PP F I+ENSPIGT I I D D GPN+ Y + Sbjct: 838 VVIVVEDENDNPPTFNQPFFLGVIAENSPIGTEIVLNNPIIISDMDAAGPNS--EYELLL 895 Query: 729 GDDSNSF 735 +SNSF Sbjct: 896 SGESNSF 902 Score = 41.9 bits (94), Expect = 0.25 Identities = 22/54 (40%), Positives = 32/54 (59%), Gaps = 2/54 (3%) Query: 11 INVLDCNDHSPVFEMQQYE--ASVREGASSGTTVLTLKATDQDIGKNAEVEYTI 62 I V+D ND++PVF + V + A+ G V+ ++ATD D G N EV YT+ Sbjct: 1555 IKVVDVNDNAPVFRDNYGPIISVVPDTANYGYAVMKVEATDDDAGSNGEVRYTL 1608 Score = 36.7 bits (81), Expect = 9.2 Identities = 24/72 (33%), Positives = 35/72 (48%), Gaps = 1/72 (1%) Query: 207 GDVSLVKTLDYEQVRSYRLVIRAQDGGSPSR-SNTTQLLINIRDVNDNAPRFYTSLFQES 265 G + +K LD E+ R+ I A+ + Q++I + D NDN P F F Sbjct: 801 GKLMTIKGLDREKQDVIRVTIIAEYFYKQRTFAGIYQVVIVVEDENDNPPTFNQPFFLGV 860 Query: 266 VSENVPIGYSIV 277 ++EN PIG IV Sbjct: 861 IAENSPIGTEIV 872 >UniRef50_A0NBP5 Cluster: ENSANGP00000031609; n=1; Anopheles gambiae str. PEST|Rep: ENSANGP00000031609 - Anopheles gambiae str. PEST Length = 369 Score = 143 bits (347), Expect = 5e-32 Identities = 129/396 (32%), Positives = 204/396 (51%), Gaps = 37/396 (9%) Query: 429 LDFKQERRYVLTVSATDSGGRSDTAMV--QINITDANNYAPVFENAPYTAS-VFEDAPIG 485 L+ + +V+ V A D+ G S +V ++ + D N++ P FE Y + + EDA I Sbjct: 2 LEHEPADTFVMQVKAHDNDGTSAHNIVSYRLEVLDKNDHPPRFEEQYYEVNNIPEDADIN 61 Query: 486 TTVLVVSATDSDVGINAQITYSLSSEISNEAVAHHDQQFVINPQTGAITTNKLLDRETMS 545 T+V+ V ATD D + +I YS+ I N + F I+ TG I+ NK LD E++ Sbjct: 62 TSVIKVKATDLDK--DPKIQYSI---IENNI----GKAFKIDEDTGLISVNKKLDYESIQ 112 Query: 546 GYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTAN-IMEDALVGTSVSQVG 604 Y L V A DG S TT++ I V+D ND+ P F++Q Y N I EDA + TSV +V Sbjct: 113 EYDLVVQAHDGLFKS---TTNLFIRVLDKNDHPPRFEEQYYEVNNIPEDADINTSVIKVK 169 Query: 605 ATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLKAVAIDGGT 664 TD D + +I Y + + + ++ ID +G+I NK LD ES+ +DL A DG Sbjct: 170 TTDLDK--DPKIKYSIIENNIGK-AYKIDEDTGLISVNKKLDYESIQEYDLVVQAHDGLF 226 Query: 665 PPQSSTVIVHIKIEDIND-SPPVFESDCLTFYISENSPIGTTIGEIRAHDPDEGPNAVVH 723 ST V I+I+++ND +P + +T I EN+ I + A+DPD + + Sbjct: 227 ---KSTTNVRIEIKNLNDIAPQILTLTNVT--IKENTIPSDCIANLWAYDPD-----IEN 276 Query: 724 YSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKY--ELVIR-AASPPLWNDVRV 780 + + D ++ R + EL ++V+ D E +K+Y ++IR + P+ ++ Sbjct: 277 FDV---DPDAPTEIKNRFQTVGDELYSLVEFDREQ-QKQYLVPILIRDSGHKPMSAVSKL 332 Query: 781 EILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRV 816 +++ D NDN M I+ NNY+ F GRV Sbjct: 333 LVVIGDKNDNEMQMGQSHILVNNYEGKFADTQIGRV 368 Score = 134 bits (324), Expect = 3e-29 Identities = 104/346 (30%), Positives = 165/346 (47%), Gaps = 45/346 (13%) Query: 7 IHQQINVLDCNDHSPVFEMQQYEAS-VREGASSGTTVLTLKATDQDIGKNAEVEYTIELV 65 + ++ VLD NDH P FE Q YE + + E A T+V+ +KATD D K+ +++Y+I Sbjct: 28 VSYRLEVLDKNDHPPRFEEQYYEVNNIPEDADINTSVIKVKATDLD--KDPKIQYSI--- 82 Query: 66 TADTLNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASP 125 + F+ID +G + LD E + Y ++V+A D Sbjct: 83 ----------------IENNIGKAFKIDEDTGLISVNKKLDYESIQEYDLVVQAHDGL-- 124 Query: 126 VSDRLSSTATIHVNIIDDNDNYPQFSEKTYTVS-VDEDISVTDNPVIAKIKATDADVGAN 184 ST + + ++D ND+ P+F E+ Y V+ + ED + N + K+K TD D + Sbjct: 125 ----FKSTTNLFIRVLDKNDHPPRFEEQYYEVNNIPEDADI--NTSVIKVKTTDLD--KD 176 Query: 185 SAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLL 244 I+Y+II N + ID +G +S+ K LDYE ++ Y LV++A DG S TT + Sbjct: 177 PKIKYSIIENNIGKAYKIDEDTGLISVNKKLDYESIQEYDLVVQAHDGLFKS---TTNVR 233 Query: 245 INIRDVNDNAPRFYTSLFQESVSENVPIGYSIVRVQAYDADEGVNAELTYTMTDKDYTGN 304 I I+++ND AP+ T L ++ EN I + AYD D D D Sbjct: 234 IEIKNLNDIAPQILT-LTNVTIKENTIPSDCIANLWAYDPD--------IENFDVDPDAP 284 Query: 305 VDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGGDPPRSATA 350 ++ +Y+ + DRE Q +Y + + D G P SA + Sbjct: 285 TEIKNRFQTVGDELYSLVEFDREQQKQYLVPILIRDSGHKPMSAVS 330 Score = 116 bits (280), Expect = 7e-24 Identities = 95/355 (26%), Positives = 167/355 (47%), Gaps = 26/355 (7%) Query: 105 LDREKVARYTVLVKATDQASPVSDRLSSTATIHVNIIDDNDNYPQFSEKTYTV-SVDEDI 163 L+ E + + VKA D + + S + ++D ND+ P+F E+ Y V ++ ED Sbjct: 2 LEHEPADTFVMQVKAHDNDGTSAHNIVS---YRLEVLDKNDHPPRFEEQYYEVNNIPEDA 58 Query: 164 SVTDNPVIAKIKATDADVGANSAIRYAIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSY 223 + N + K+KATD D + I+Y+II N F ID +G +S+ K LDYE ++ Y Sbjct: 59 DI--NTSVIKVKATDLD--KDPKIQYSIIENNIGKAFKIDEDTGLISVNKKLDYESIQEY 114 Query: 224 RLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ-ESVSENVPIGYSIVRVQAY 282 LV++A DG S TT L I + D ND+ PRF ++ ++ E+ I S+++V+ Sbjct: 115 DLVVQAHDGLFKS---TTNLFIRVLDKNDHPPRFEEQYYEVNNIPEDADINTSVIKVKTT 171 Query: 283 DADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQLLVTATDGG 342 D D+ + ++ Y++ + N+ ID +G + + +LD E+ +Y L+V A DG Sbjct: 172 DLDK--DPKIKYSIIE----NNIGKAYKIDEDTGLISVNKKLDYESIQEYDLVVQAHDG- 224 Query: 343 DPPRSATATXXXXXXXXXXXXXXFMPGQYEVELAEDEPPGTPVVTLTATDADEDNRLHYE 402 + T + V + E+ P + L A D D +N Sbjct: 225 ---LFKSTTNVRIEIKNLNDIAPQILTLTNVTIKENTIPSDCIANLWAYDPDIENFDVDP 281 Query: 403 ITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDTAMVQI 457 + RF L+ D +Q+++Y++ + DSG + +A+ ++ Sbjct: 282 DAPTEIKNRFQTVGDELYSLV----EFDREQQKQYLVPILIRDSGHKPMSAVSKL 332 Score = 109 bits (263), Expect = 8e-22 Identities = 97/391 (24%), Positives = 168/391 (42%), Gaps = 26/391 (6%) Query: 215 LDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRDVNDNAPRFYTSLFQ-ESVSENVPIG 273 L++E ++ + ++A D S N + + D ND+ PRF ++ ++ E+ I Sbjct: 2 LEHEPADTFVMQVKAHDNDGTSAHNIVSYRLEVLDKNDHPPRFEEQYYEVNNIPEDADIN 61 Query: 274 YSIVRVQAYDADEGVNAELTYTMTDKDYTGNVDLPITIDPRSGWVYTSGQLDRETQAKYQ 333 S+++V+A D D+ + ++ Y++ + N+ ID +G + + +LD E+ +Y Sbjct: 62 TSVIKVKATDLDK--DPKIQYSIIEN----NIGKAFKIDEDTGLISVNKKLDYESIQEYD 115 Query: 334 LLVTATDGGDPPRSATATXXXXXXXXXXXXXXFMPGQYEVE-LAEDEPPGTPVVTLTATD 392 L+V A DG +T F YEV + ED T V+ + TD Sbjct: 116 LVVQAHDG---LFKSTTNLFIRVLDKNDHPPRFEEQYYEVNNIPEDADINTSVIKVKTTD 172 Query: 393 ADEDNRLHYEITGGNTRGRFSITSQNGRGLITVAQPLDFKQERRYVLTVSATDSGGRSDT 452 D+D ++ Y I N + I G LI+V + LD++ + Y L V A D +S T Sbjct: 173 LDKDPKIKYSIIENNIGKAYKIDEDTG--LISVNKKLDYESIQEYDLVVQAHDGLFKS-T 229 Query: 453 AMVQINITDANNYAPVFENAPYTASVFEDAPIGTTVLVVSATDSDVGINAQITYSLSSEI 512 V+I I + N+ AP ++ E+ + + A D D+ N + +EI Sbjct: 230 TNVRIEIKNLNDIAPQILTLT-NVTIKENTIPSDCIANLWAYDPDIE-NFDVDPDAPTEI 287 Query: 513 SNEAVAHHDQQFVINPQTGAITTNKLLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVV 572 N D+ + + DRE YL+ + RD G +S + + + + Sbjct: 288 KNRFQTVGDELYSLVE----------FDREQQKQYLVPILIRDSGHKPMSAVSKLLVVIG 337 Query: 573 DVNDNEPVFKQQLYTANIMEDALVGTSVSQV 603 D NDNE Q N E T + +V Sbjct: 338 DKNDNEMQMGQSHILVNNYEGKFADTQIGRV 368 Score = 108 bits (260), Expect = 2e-21 Identities = 86/288 (29%), Positives = 142/288 (49%), Gaps = 16/288 (5%) Query: 538 LLDRETMSGYLLTVTARDGGVPSLSDTTDVEISVVDVNDNEPVFKQQLYTA-NIMEDALV 596 +L+ E +++ V A D S + + V+D ND+ P F++Q Y NI EDA + Sbjct: 1 ILEHEPADTFVMQVKAHDNDGTSAHNIVSYRLEVLDKNDHPPRFEEQYYEVNNIPEDADI 60 Query: 597 GTSVSQVGATDADVGLNGRIHYELDPKDREEGSFVIDPASGVIRTNKALDRESVATHDLK 656 TSV +V ATD D + +I Y + + + +F ID +G+I NK LD ES+ +DL Sbjct: 61 NTSVIKVKATDLD--KDPKIQYSIIENNIGK-AFKIDEDTGLISVNKKLDYESIQEYDLV 117 Query: 657 AVAIDGGTPPQSSTVIVHIKIEDINDSPPVFESDCLTF-YISENSPIGTTIGEIRAHDPD 715 A DG ST + I++ D ND PP FE I E++ I T++ +++ D D Sbjct: 118 VQAHDG---LFKSTTNLFIRVLDKNDHPPRFEEQYYEVNNIPEDADINTSVIKVKTTDLD 174 Query: 716 EGPNAVVHYSIKGGDDSNSFSLETRQGSDKAELVTMVDLDYESPRKKYELVIRAASPPLW 775 + P + YSI + ++ ++ D + LDYES ++Y+LV++A Sbjct: 175 KDPK--IKYSIIENNIGKAYKID----EDTGLISVNKKLDYES-IQEYDLVVQAHDGLFK 227 Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFGRVPAYDADV 823 + V I + ++ND AP + + ++ P + AYD D+ Sbjct: 228 STTNVRIEIKNLNDIAPQILTLTNV-TIKENTIPSDCIANLWAYDPDI 274 Score = 68.5 bits (160), Expect = 2e-09 Identities = 72/244 (29%), Positives = 108/244 (44%), Gaps = 35/244 (14%) Query: 11 INVLDCNDHSPVFEMQQYEAS-VREGASSGTTVLTLKATDQDIGKNAEVEYTIELVTADT 69 I VLD NDH P FE Q YE + + E A T+V+ +K TD D K+ +++Y+I Sbjct: 133 IRVLDKNDHPPRFEEQYYEVNNIPEDADINTSVIKVKTTDLD--KDPKIKYSI------- 183 Query: 70 LNPEDAXXXXXXXXXXVQDVFRIDGRSGALLTRASLDREKVARYTVLVKATDQASPVSDR 129 + ++ID +G + LD E + Y ++V+A D Sbjct: 184 ------------IENNIGKAYKIDEDTGLISVNKKLDYESIQEYDLVVQAHDGL------ 225 Query: 130 LSSTATIHVNIIDDNDNYPQFSEKTYTVSVDEDISVTDNPVIAKIKATDADVGANSAIRY 189 ST + + I + ND PQ T V++ E+ +D IA + A D D+ Sbjct: 226 FKSTTNVRIEIKNLNDIAPQILTLT-NVTIKENTIPSD--CIANLWAYDPDIENFDVDPD 282 Query: 190 AIIGGNTQMQFSIDSLSGDVSLVKTLDYEQVRSYRLVIRAQDGGSPSRSNTTQLLINIRD 249 A + Q D L SLV+ D EQ + Y + I +D G S ++LL+ I D Sbjct: 283 APTEIKNRFQTVGDEL---YSLVE-FDREQQKQYLVPILIRDSGHKPMSAVSKLLVVIGD 338 Query: 250 VNDN 253 NDN Sbjct: 339 KNDN 342 Score = 37.5 bits (83), Expect = 5.3 Identities = 28/113 (24%), Positives = 52/113 (46%), Gaps = 3/113 (2%) Query: 776 NDVRVEILVTDVNDNAPVMKDFQIIFNNYKDCFPVGPFG-RVPAYDADVTDKLQYRILSG 834 N V + V D ND+ P ++ NN + + +V A D D K+QY I+ Sbjct: 26 NIVSYRLEVLDKNDHPPRFEEQYYEVNNIPEDADINTSVIKVKATDLDKDPKIQYSIIEN 85 Query: 835 NNANLILLNETTGSMTLSPQLNTNVPKLATMEVSVTDGVNEIKAMMQLSVRLI 887 N ++E TG ++++ +L+ + + V DG+ K+ L +R++ Sbjct: 86 NIGKAFKIDEDTGLISVNKKLDYESIQEYDLVVQAHDGL--FKSTTNLFIRVL 136 Database: uniref50 Posted date: Oct 5, 2007 11:19 AM Number of letters in database: 575,637,011 Number of sequences in database: 1,657,284 Lambda K H 0.317 0.134 0.404 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 3,126,570,439 Number of Sequences: 1657284 Number of extensions: 138148970 Number of successful extensions: 382967 Number of sequences better than 10.0: 500 Number of HSP's better than 10.0 without gapping: 923 Number of HSP's successfully gapped in prelim test: 1082 Number of HSP's that attempted gapping in prelim test: 323038 Number of HSP's gapped (non-prelim): 31612 length of query: 2796 length of database: 575,637,011 effective HSP length: 114 effective length of query: 2682 effective length of database: 386,706,635 effective search space: 1037147195070 effective search space used: 1037147195070 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits) S2: 81 (36.7 bits)
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